Mitch Report

date generated: 2020-07-02

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

##                   x
## A1BG      2.6245484
## A1BG-AS1  0.4968992
## A1CF      0.5554787
## A2M      -3.2184650
## A2M-AS1  -3.0532140
## A2ML1    -0.3470803

Here are some metrics about the input data profile:

Profile metrics

	Profile metrics
num_genesets	2400
num_genes_in_profile	21907
duplicated_genes_present	0
num_profile_genes_in_sets	8459
num_profile_genes_not_in_sets	13448

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt

Gene sets metrics

	Gene sets metrics
num_genesets	2400
num_genesets_excluded	1036
num_genesets_included	1364

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 100 gene sets

set	setSize	pANOVA	s.dist	p.adjustANOVA
Neutrophil degranulation	458	0.00e+00	0.5850	5.00e-100
Innate Immune System	968	8.43e-85	0.3690	5.75e-82
Immune System	1894	1.88e-46	0.1980	8.53e-44
Membrane Trafficking	559	7.39e-36	0.3090	2.52e-33
Vesicle-mediated transport	650	3.62e-32	0.2710	9.87e-30
Signal Transduction	1894	8.20e-28	0.1520	1.86e-25
Hemostasis	550	4.64e-24	0.2520	9.04e-22
Metabolism	1772	3.22e-22	0.1390	5.48e-20
Signaling by Receptor Tyrosine Kinases	414	1.08e-20	0.2670	1.63e-18
Platelet activation, signaling and aggregation	221	1.26e-20	0.3630	1.71e-18
Signaling by Interleukins	386	1.86e-19	0.2670	2.30e-17
Metabolism of proteins	1719	6.35e-19	0.1290	7.21e-17
Post-translational protein modification	1194	1.26e-18	0.1510	1.32e-16
Response to elevated platelet cytosolic Ca2+	110	1.59e-16	0.4550	1.55e-14
Platelet degranulation	106	7.21e-16	0.4530	6.56e-14
Toll-like Receptor Cascades	143	3.06e-15	0.3820	2.61e-13
Asparagine N-linked glycosylation	269	8.72e-15	0.2750	6.99e-13
Disease	1303	1.03e-14	0.1270	7.80e-13
Metabolism of lipids	625	1.26e-14	0.1810	9.04e-13
Transport of small molecules	561	2.09e-14	0.1890	1.42e-12
Toll Like Receptor 4 (TLR4) Cascade	121	4.08e-14	0.3980	2.65e-12
rRNA processing	219	1.68e-13	-0.2890	1.04e-11
rRNA processing in the nucleus and cytosol	190	2.49e-13	-0.3080	1.48e-11
Signaling by NOTCH	183	3.32e-13	0.3120	1.79e-11
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	92	3.67e-13	0.4380	1.79e-11
Toll Like Receptor 2 (TLR2) Cascade	92	3.67e-13	0.4380	1.79e-11
Toll Like Receptor TLR1:TLR2 Cascade	92	3.67e-13	0.4380	1.79e-11
Toll Like Receptor TLR6:TLR2 Cascade	92	3.67e-13	0.4380	1.79e-11
ER to Golgi Anterograde Transport	129	4.27e-13	0.3690	2.01e-11
Interleukin-1 signaling	98	6.36e-13	0.4200	2.89e-11
Major pathway of rRNA processing in the nucleolus and cytosol	180	1.17e-12	-0.3070	5.16e-11
Diseases of signal transduction by growth factor receptors and second messengers	343	1.26e-12	0.2230	5.36e-11
Clathrin-mediated endocytosis	127	3.18e-12	0.3580	1.32e-10
Signaling by Rho GTPases	367	4.55e-12	0.2100	1.82e-10
Interleukin-1 family signaling	125	1.10e-11	0.3520	4.29e-10
Signaling by NTRKs	116	1.21e-11	0.3640	4.60e-10
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	88	1.75e-11	0.4150	6.45e-10
Antigen processing-Cross presentation	98	2.10e-11	0.3910	7.55e-10
Transport to the Golgi and subsequent modification	155	2.18e-11	0.3110	7.63e-10
RHO GTPase Effectors	250	2.84e-11	0.2440	9.69e-10
MyD88 dependent cascade initiated on endosome	89	5.33e-11	0.4020	1.73e-09
Toll Like Receptor 7/8 (TLR7/8) Cascade	89	5.33e-11	0.4020	1.73e-09
Toll Like Receptor 9 (TLR9) Cascade	93	9.72e-11	0.3880	3.08e-09
Signaling by NTRK1 (TRKA)	101	1.65e-10	0.3680	5.11e-09
Translocation of ZAP-70 to Immunological synapse	24	2.76e-10	-0.7440	8.37e-09
Gene expression (Transcription)	1335	3.26e-10	-0.1020	9.66e-09
RHO GTPases Activate WASPs and WAVEs	35	5.30e-10	0.6060	1.54e-08
Intra-Golgi and retrograde Golgi-to-ER traffic	179	5.47e-10	0.2690	1.56e-08
MyD88 cascade initiated on plasma membrane	82	6.02e-10	0.3950	1.61e-08
Toll Like Receptor 10 (TLR10) Cascade	82	6.02e-10	0.3950	1.61e-08
Toll Like Receptor 5 (TLR5) Cascade	82	6.02e-10	0.3950	1.61e-08
Developmental Biology	732	8.35e-10	0.1330	2.19e-08
EPH-Ephrin signaling	79	1.33e-09	0.3940	3.43e-08
Golgi-to-ER retrograde transport	111	1.85e-09	0.3300	4.68e-08
Programmed Cell Death	171	2.39e-09	0.2640	5.83e-08
COPI-mediated anterograde transport	78	2.39e-09	0.3910	5.83e-08
Amyloid fiber formation	51	2.47e-09	0.4830	5.83e-08
Apoptosis	168	2.48e-09	0.2670	5.83e-08
Autophagy	124	2.60e-09	0.3100	6.02e-08
Signaling by WNT	254	3.12e-09	0.2160	7.10e-08
RHO GTPases activate PKNs	48	6.59e-09	0.4840	1.47e-07
ROS and RNS production in phagocytes	31	7.98e-09	0.5980	1.75e-07
MyD88-independent TLR4 cascade	96	8.80e-09	0.3400	1.88e-07
TRIF(TICAM1)-mediated TLR4 signaling	96	8.80e-09	0.3400	1.88e-07
Generic Transcription Pathway	1085	9.34e-09	-0.1030	1.96e-07
COPI-independent Golgi-to-ER retrograde traffic	33	2.42e-08	0.5610	5.00e-07
ER-Phagosome pathway	83	2.45e-08	0.3540	5.00e-07
Cellular responses to external stimuli	506	2.59e-08	0.1450	5.20e-07
Cellular response to hypoxia	72	3.91e-08	0.3740	7.65e-07
Detoxification of Reactive Oxygen Species	32	3.93e-08	0.5610	7.65e-07
Signaling by Nuclear Receptors	217	4.03e-08	0.2160	7.75e-07
Cargo recognition for clathrin-mediated endocytosis	90	4.62e-08	0.3330	8.64e-07
RUNX1 regulates transcription of genes involved in differentiation of HSCs	83	4.63e-08	0.3470	8.64e-07
Infectious disease	724	4.92e-08	0.1190	9.06e-07
Class I MHC mediated antigen processing & presentation	350	5.20e-08	0.1690	9.45e-07
The citric acid (TCA) cycle and respiratory electron transport	172	6.43e-08	0.2390	1.15e-06
COPII-mediated vesicle transport	65	6.58e-08	0.3870	1.17e-06
ESR-mediated signaling	161	7.12e-08	0.2460	1.25e-06
Cellular responses to stress	500	7.40e-08	0.1410	1.28e-06
trans-Golgi Network Vesicle Budding	69	9.74e-08	0.3710	1.66e-06
PD-1 signaling	28	1.17e-07	-0.5780	1.97e-06
rRNA modification in the nucleus and cytosol	59	1.46e-07	-0.3960	2.42e-06
RAB GEFs exchange GTP for GDP on RABs	88	1.64e-07	0.3230	2.70e-06
Rab regulation of trafficking	121	1.71e-07	0.2750	2.77e-06
MAP2K and MAPK activation	34	1.76e-07	0.5170	2.82e-06
DNA strand elongation	32	2.48e-07	-0.5270	3.94e-06
Post-translational protein phosphorylation	70	3.12e-07	0.3540	4.90e-06
tRNA processing	136	3.25e-07	-0.2540	5.04e-06
CLEC7A (Dectin-1) signaling	97	3.39e-07	0.3000	5.20e-06
Signaling by BRAF and RAF fusions	57	3.58e-07	0.3900	5.43e-06
Intracellular signaling by second messengers	273	3.71e-07	0.1790	5.56e-06
RNA Polymerase II Transcription	1204	3.79e-07	-0.0869	5.61e-06
C-type lectin receptors (CLRs)	129	4.08e-07	0.2580	5.92e-06
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	124	4.08e-07	0.2630	5.92e-06
VEGFA-VEGFR2 Pathway	92	4.79e-07	0.3040	6.88e-06
MAP kinase activation	63	5.02e-07	0.3660	7.14e-06
Selenocysteine synthesis	92	6.15e-07	-0.3010	8.64e-06
Transcriptional regulation of granulopoiesis	46	6.81e-07	0.4230	9.48e-06
PIP3 activates AKT signaling	241	7.21e-07	0.1850	9.79e-06
Signaling by NOTCH4	79	7.25e-07	0.3220	9.79e-06

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
Neutrophil degranulation	458	0.00e+00	0.585000	5.00e-100
Innate Immune System	968	8.43e-85	0.369000	5.75e-82
Immune System	1894	1.88e-46	0.198000	8.53e-44
Membrane Trafficking	559	7.39e-36	0.309000	2.52e-33
Vesicle-mediated transport	650	3.62e-32	0.271000	9.87e-30
Signal Transduction	1894	8.20e-28	0.152000	1.86e-25
Hemostasis	550	4.64e-24	0.252000	9.04e-22
Metabolism	1772	3.22e-22	0.139000	5.48e-20
Signaling by Receptor Tyrosine Kinases	414	1.08e-20	0.267000	1.63e-18
Platelet activation, signaling and aggregation	221	1.26e-20	0.363000	1.71e-18
Signaling by Interleukins	386	1.86e-19	0.267000	2.30e-17
Metabolism of proteins	1719	6.35e-19	0.129000	7.21e-17
Post-translational protein modification	1194	1.26e-18	0.151000	1.32e-16
Response to elevated platelet cytosolic Ca2+	110	1.59e-16	0.455000	1.55e-14
Platelet degranulation	106	7.21e-16	0.453000	6.56e-14
Toll-like Receptor Cascades	143	3.06e-15	0.382000	2.61e-13
Asparagine N-linked glycosylation	269	8.72e-15	0.275000	6.99e-13
Disease	1303	1.03e-14	0.127000	7.80e-13
Metabolism of lipids	625	1.26e-14	0.181000	9.04e-13
Transport of small molecules	561	2.09e-14	0.189000	1.42e-12
Toll Like Receptor 4 (TLR4) Cascade	121	4.08e-14	0.398000	2.65e-12
rRNA processing	219	1.68e-13	-0.289000	1.04e-11
rRNA processing in the nucleus and cytosol	190	2.49e-13	-0.308000	1.48e-11
Signaling by NOTCH	183	3.32e-13	0.312000	1.79e-11
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	92	3.67e-13	0.438000	1.79e-11
Toll Like Receptor 2 (TLR2) Cascade	92	3.67e-13	0.438000	1.79e-11
Toll Like Receptor TLR1:TLR2 Cascade	92	3.67e-13	0.438000	1.79e-11
Toll Like Receptor TLR6:TLR2 Cascade	92	3.67e-13	0.438000	1.79e-11
ER to Golgi Anterograde Transport	129	4.27e-13	0.369000	2.01e-11
Interleukin-1 signaling	98	6.36e-13	0.420000	2.89e-11
Major pathway of rRNA processing in the nucleolus and cytosol	180	1.17e-12	-0.307000	5.16e-11
Diseases of signal transduction by growth factor receptors and second messengers	343	1.26e-12	0.223000	5.36e-11
Clathrin-mediated endocytosis	127	3.18e-12	0.358000	1.32e-10
Signaling by Rho GTPases	367	4.55e-12	0.210000	1.82e-10
Interleukin-1 family signaling	125	1.10e-11	0.352000	4.29e-10
Signaling by NTRKs	116	1.21e-11	0.364000	4.60e-10
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	88	1.75e-11	0.415000	6.45e-10
Antigen processing-Cross presentation	98	2.10e-11	0.391000	7.55e-10
Transport to the Golgi and subsequent modification	155	2.18e-11	0.311000	7.63e-10
RHO GTPase Effectors	250	2.84e-11	0.244000	9.69e-10
MyD88 dependent cascade initiated on endosome	89	5.33e-11	0.402000	1.73e-09
Toll Like Receptor 7/8 (TLR7/8) Cascade	89	5.33e-11	0.402000	1.73e-09
Toll Like Receptor 9 (TLR9) Cascade	93	9.72e-11	0.388000	3.08e-09
Signaling by NTRK1 (TRKA)	101	1.65e-10	0.368000	5.11e-09
Translocation of ZAP-70 to Immunological synapse	24	2.76e-10	-0.744000	8.37e-09
Gene expression (Transcription)	1335	3.26e-10	-0.102000	9.66e-09
RHO GTPases Activate WASPs and WAVEs	35	5.30e-10	0.606000	1.54e-08
Intra-Golgi and retrograde Golgi-to-ER traffic	179	5.47e-10	0.269000	1.56e-08
MyD88 cascade initiated on plasma membrane	82	6.02e-10	0.395000	1.61e-08
Toll Like Receptor 10 (TLR10) Cascade	82	6.02e-10	0.395000	1.61e-08
Toll Like Receptor 5 (TLR5) Cascade	82	6.02e-10	0.395000	1.61e-08
Developmental Biology	732	8.35e-10	0.133000	2.19e-08
EPH-Ephrin signaling	79	1.33e-09	0.394000	3.43e-08
Golgi-to-ER retrograde transport	111	1.85e-09	0.330000	4.68e-08
Programmed Cell Death	171	2.39e-09	0.264000	5.83e-08
COPI-mediated anterograde transport	78	2.39e-09	0.391000	5.83e-08
Amyloid fiber formation	51	2.47e-09	0.483000	5.83e-08
Apoptosis	168	2.48e-09	0.267000	5.83e-08
Autophagy	124	2.60e-09	0.310000	6.02e-08
Signaling by WNT	254	3.12e-09	0.216000	7.10e-08
RHO GTPases activate PKNs	48	6.59e-09	0.484000	1.47e-07
ROS and RNS production in phagocytes	31	7.98e-09	0.598000	1.75e-07
MyD88-independent TLR4 cascade	96	8.80e-09	0.340000	1.88e-07
TRIF(TICAM1)-mediated TLR4 signaling	96	8.80e-09	0.340000	1.88e-07
Generic Transcription Pathway	1085	9.34e-09	-0.103000	1.96e-07
COPI-independent Golgi-to-ER retrograde traffic	33	2.42e-08	0.561000	5.00e-07
ER-Phagosome pathway	83	2.45e-08	0.354000	5.00e-07
Cellular responses to external stimuli	506	2.59e-08	0.145000	5.20e-07
Cellular response to hypoxia	72	3.91e-08	0.374000	7.65e-07
Detoxification of Reactive Oxygen Species	32	3.93e-08	0.561000	7.65e-07
Signaling by Nuclear Receptors	217	4.03e-08	0.216000	7.75e-07
Cargo recognition for clathrin-mediated endocytosis	90	4.62e-08	0.333000	8.64e-07
RUNX1 regulates transcription of genes involved in differentiation of HSCs	83	4.63e-08	0.347000	8.64e-07
Infectious disease	724	4.92e-08	0.119000	9.06e-07
Class I MHC mediated antigen processing & presentation	350	5.20e-08	0.169000	9.45e-07
The citric acid (TCA) cycle and respiratory electron transport	172	6.43e-08	0.239000	1.15e-06
COPII-mediated vesicle transport	65	6.58e-08	0.387000	1.17e-06
ESR-mediated signaling	161	7.12e-08	0.246000	1.25e-06
Cellular responses to stress	500	7.40e-08	0.141000	1.28e-06
trans-Golgi Network Vesicle Budding	69	9.74e-08	0.371000	1.66e-06
PD-1 signaling	28	1.17e-07	-0.578000	1.97e-06
rRNA modification in the nucleus and cytosol	59	1.46e-07	-0.396000	2.42e-06
RAB GEFs exchange GTP for GDP on RABs	88	1.64e-07	0.323000	2.70e-06
Rab regulation of trafficking	121	1.71e-07	0.275000	2.77e-06
MAP2K and MAPK activation	34	1.76e-07	0.517000	2.82e-06
DNA strand elongation	32	2.48e-07	-0.527000	3.94e-06
Post-translational protein phosphorylation	70	3.12e-07	0.354000	4.90e-06
tRNA processing	136	3.25e-07	-0.254000	5.04e-06
CLEC7A (Dectin-1) signaling	97	3.39e-07	0.300000	5.20e-06
Signaling by BRAF and RAF fusions	57	3.58e-07	0.390000	5.43e-06
Intracellular signaling by second messengers	273	3.71e-07	0.179000	5.56e-06
RNA Polymerase II Transcription	1204	3.79e-07	-0.086900	5.61e-06
C-type lectin receptors (CLRs)	129	4.08e-07	0.258000	5.92e-06
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	124	4.08e-07	0.263000	5.92e-06
VEGFA-VEGFR2 Pathway	92	4.79e-07	0.304000	6.88e-06
MAP kinase activation	63	5.02e-07	0.366000	7.14e-06
Selenocysteine synthesis	92	6.15e-07	-0.301000	8.64e-06
Transcriptional regulation of granulopoiesis	46	6.81e-07	0.423000	9.48e-06
PIP3 activates AKT signaling	241	7.21e-07	0.185000	9.79e-06
Signaling by NOTCH4	79	7.25e-07	0.322000	9.79e-06
Toll Like Receptor 3 (TLR3) Cascade	92	7.25e-07	0.299000	9.79e-06
Signaling by MET	61	7.70e-07	0.366000	1.03e-05
Generation of second messenger molecules	38	7.90e-07	-0.463000	1.05e-05
Cytokine Signaling in Immune system	736	8.49e-07	0.107000	1.11e-05
Oncogenic MAPK signaling	73	8.66e-07	0.333000	1.12e-05
IRAK4 deficiency (TLR2/4)	10	8.80e-07	0.898000	1.12e-05
MyD88 deficiency (TLR2/4)	10	8.80e-07	0.898000	1.12e-05
Cargo concentration in the ER	30	8.85e-07	0.518000	1.12e-05
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	65	8.91e-07	0.352000	1.12e-05
Macroautophagy	110	9.07e-07	0.271000	1.12e-05
Pre-NOTCH Expression and Processing	65	1.01e-06	0.351000	1.24e-05
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	80	1.02e-06	0.316000	1.24e-05
EPHB-mediated forward signaling	32	1.02e-06	0.499000	1.24e-05
Extracellular matrix organization	219	1.06e-06	0.191000	1.27e-05
Phosphorylation of CD3 and TCR zeta chains	27	1.11e-06	-0.541000	1.32e-05
Endosomal Sorting Complex Required For Transport (ESCRT)	29	1.26e-06	0.520000	1.48e-05
L1CAM interactions	85	1.30e-06	0.304000	1.52e-05
RAB geranylgeranylation	61	1.40e-06	0.357000	1.62e-05
Signaling by high-kinase activity BRAF mutants	31	1.54e-06	0.499000	1.77e-05
Interleukin-4 and Interleukin-13 signaling	92	1.63e-06	0.289000	1.84e-05
Interleukin-17 signaling	68	1.63e-06	0.336000	1.84e-05
PCP/CE pathway	87	1.77e-06	0.296000	1.98e-05
Activation of the pre-replicative complex	32	1.82e-06	-0.487000	2.02e-05
Smooth Muscle Contraction	31	1.95e-06	0.494000	2.15e-05
Signaling by RAF1 mutants	34	1.98e-06	0.471000	2.16e-05
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism	12	2.31e-06	0.787000	2.48e-05
alpha-linolenic acid (ALA) metabolism	12	2.31e-06	0.787000	2.48e-05
Golgi Associated Vesicle Biogenesis	55	2.37e-06	0.368000	2.52e-05
TCF dependent signaling in response to WNT	166	2.53e-06	0.212000	2.68e-05
PPARA activates gene expression	104	2.67e-06	0.266000	2.80e-05
Hh mutants that don't undergo autocatalytic processing are degraded by ERAD	54	2.74e-06	0.369000	2.84e-05
RNA Polymerase I Promoter Opening	19	2.76e-06	0.621000	2.84e-05
Defective CFTR causes cystic fibrosis	60	2.77e-06	0.350000	2.84e-05
Iron uptake and transport	52	2.91e-06	0.375000	2.96e-05
Protein ubiquitination	72	2.97e-06	0.318000	3.00e-05
MAPK family signaling cascades	270	3.26e-06	0.164000	3.27e-05
Budding and maturation of HIV virion	26	3.43e-06	0.526000	3.42e-05
Integration of energy metabolism	86	3.48e-06	0.289000	3.44e-05
Signaling by VEGF	100	3.61e-06	0.268000	3.54e-05
Regulation of PTEN stability and activity	67	3.65e-06	0.327000	3.55e-05
Respiratory electron transport	101	3.84e-06	0.266000	3.71e-05
Beta-catenin independent WNT signaling	137	3.93e-06	0.228000	3.77e-05
Paradoxical activation of RAF signaling by kinase inactive BRAF	38	4.07e-06	0.432000	3.80e-05
Signaling by RAS mutants	38	4.07e-06	0.432000	3.80e-05
Signaling by moderate kinase activity BRAF mutants	38	4.07e-06	0.432000	3.80e-05
Signaling downstream of RAS mutants	38	4.07e-06	0.432000	3.80e-05
Deubiquitination	242	4.12e-06	0.172000	3.82e-05
Peptide chain elongation	88	4.47e-06	-0.283000	4.12e-05
Antimicrobial peptides	33	4.52e-06	0.461000	4.14e-05
Regulation of mRNA stability by proteins that bind AU-rich elements	88	4.60e-06	0.283000	4.19e-05
Eukaryotic Translation Elongation	93	4.78e-06	-0.274000	4.32e-05
Influenza Viral RNA Transcription and Replication	135	5.72e-06	-0.226000	5.14e-05
Cross-presentation of soluble exogenous antigens (endosomes)	48	5.93e-06	0.378000	5.29e-05
Hedgehog ligand biogenesis	59	6.36e-06	0.340000	5.63e-05
Insulin receptor recycling	21	6.66e-06	0.568000	5.86e-05
Activation of ATR in response to replication stress	37	6.89e-06	-0.427000	6.03e-05
Transferrin endocytosis and recycling	26	7.09e-06	0.509000	6.16e-05
Regulation of ornithine decarboxylase (ODC)	50	7.19e-06	0.367000	6.21e-05
Hh mutants abrogate ligand secretion	55	7.36e-06	0.349000	6.32e-05
Negative regulation of NOTCH4 signaling	54	7.75e-06	0.352000	6.61e-05
Regulation of lipid metabolism by PPARalpha	106	8.03e-06	0.251000	6.80e-05
Platelet Aggregation (Plug Formation)	28	8.14e-06	0.487000	6.85e-05
ABC transporter disorders	71	8.47e-06	0.306000	7.09e-05
Diseases associated with the TLR signaling cascade	23	8.58e-06	0.536000	7.09e-05
Diseases of Immune System	23	8.58e-06	0.536000	7.09e-05
Hyaluronan uptake and degradation	12	9.15e-06	0.739000	7.52e-05
Phospholipid metabolism	185	9.40e-06	0.189000	7.68e-05
RHO GTPases Activate NADPH Oxidases	21	9.46e-06	0.558000	7.68e-05
AUF1 (hnRNP D0) binds and destabilizes mRNA	54	9.55e-06	0.348000	7.71e-05
MAPK1/MAPK3 signaling	236	9.87e-06	0.167000	7.92e-05
Axon guidance	457	1.01e-05	0.120000	8.04e-05
Eukaryotic Translation Termination	92	1.07e-05	-0.266000	8.47e-05
Degradation of DVL	55	1.09e-05	0.343000	8.56e-05
Metabolism of carbohydrates	244	1.31e-05	0.162000	1.02e-04
PTEN Regulation	139	1.39e-05	0.213000	1.08e-04
Degradation of GLI2 by the proteasome	57	1.40e-05	0.333000	1.08e-04
Regulation of activated PAK-2p34 by proteasome mediated degradation	49	1.49e-05	0.358000	1.15e-04
FLT3 Signaling	245	1.54e-05	0.160000	1.17e-04
Opioid Signalling	75	1.55e-05	0.289000	1.17e-04
Degradation of GLI1 by the proteasome	58	1.55e-05	0.328000	1.17e-04
Pre-NOTCH Transcription and Translation	49	1.63e-05	0.356000	1.23e-04
Leishmania infection	245	1.81e-05	0.159000	1.36e-04
Vif-mediated degradation of APOBEC3G	53	1.85e-05	0.340000	1.38e-04
Viral mRNA Translation	88	1.91e-05	-0.264000	1.41e-04
Nervous system development	476	1.99e-05	0.114000	1.47e-04
Regulation of TLR by endogenous ligand	11	2.02e-05	0.742000	1.48e-04
Glycerophospholipid biosynthesis	106	2.03e-05	0.240000	1.48e-04
NIK-->noncanonical NF-kB signaling	58	2.09e-05	0.323000	1.52e-04
HDACs deacetylate histones	47	2.13e-05	0.358000	1.54e-04
Selenoamino acid metabolism	114	2.24e-05	-0.230000	1.61e-04
Senescence-Associated Secretory Phenotype (SASP)	66	2.37e-05	0.301000	1.70e-04
Regulation of Apoptosis	52	2.40e-05	0.339000	1.71e-04
Dectin-1 mediated noncanonical NF-kB signaling	59	2.55e-05	0.317000	1.81e-04
The role of GTSE1 in G2/M progression after G2 checkpoint	59	2.80e-05	0.315000	1.97e-04
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	53	2.81e-05	0.332000	1.97e-04
HSP90 chaperone cycle for steroid hormone receptors (SHR)	36	2.82e-05	0.403000	1.97e-04
Oxidative Stress Induced Senescence	79	2.96e-05	0.272000	2.05e-04
GLI3 is processed to GLI3R by the proteasome	58	3.11e-05	0.316000	2.15e-04
MAPK6/MAPK4 signaling	83	3.44e-05	0.263000	2.35e-04
Metabolism of polyamines	58	3.44e-05	0.314000	2.35e-04
Erythrocytes take up carbon dioxide and release oxygen	11	3.56e-05	0.720000	2.40e-04
O2/CO2 exchange in erythrocytes	11	3.56e-05	0.720000	2.40e-04
RAF/MAP kinase cascade	231	3.79e-05	0.157000	2.54e-04
Activation of NF-kappaB in B cells	66	3.79e-05	0.293000	2.54e-04
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	94	3.81e-05	-0.246000	2.54e-04
EGFR downregulation	27	3.88e-05	0.457000	2.57e-04
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	21	4.48e-05	0.514000	2.94e-04
Neurodegenerative Diseases	21	4.48e-05	0.514000	2.94e-04
Translocation of SLC2A4 (GLUT4) to the plasma membrane	48	5.15e-05	0.338000	3.36e-04
E3 ubiquitin ligases ubiquitinate target proteins	52	5.18e-05	0.324000	3.37e-04
DNA methylation	20	5.29e-05	0.522000	3.42e-04
Degradation of beta-catenin by the destruction complex	84	5.37e-05	0.255000	3.45e-04
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	51	5.44e-05	0.327000	3.45e-04
p53-Independent DNA Damage Response	51	5.44e-05	0.327000	3.45e-04
p53-Independent G1/S DNA damage checkpoint	51	5.44e-05	0.327000	3.45e-04
Nuclear Events (kinase and transcription factor activation)	53	5.73e-05	0.319000	3.62e-04
Signal amplification	28	6.14e-05	0.437000	3.86e-04
Ub-specific processing proteases	171	6.23e-05	0.177000	3.89e-04
Late endosomal microautophagy	30	6.24e-05	0.422000	3.89e-04
Metabolism of RNA	688	6.49e-05	-0.089300	4.02e-04
Homologous DNA Pairing and Strand Exchange	42	6.53e-05	-0.356000	4.02e-04
Vpu mediated degradation of CD4	51	6.53e-05	0.323000	4.02e-04
Neddylation	219	6.71e-05	0.156000	4.10e-04
Cellular Senescence	144	6.74e-05	0.192000	4.10e-04
RHO GTPases Activate ROCKs	18	7.25e-05	0.540000	4.39e-04
Infection with Mycobacterium tuberculosis	26	7.67e-05	0.448000	4.63e-04
Lysosome Vesicle Biogenesis	32	7.71e-05	0.404000	4.63e-04
Platelet homeostasis	70	8.49e-05	0.272000	5.08e-04
SARS-CoV Infections	83	8.57e-05	0.249000	5.11e-04
Signalling to ERKs	32	8.82e-05	0.400000	5.23e-04
Regulation of RUNX3 expression and activity	55	8.98e-05	0.305000	5.30e-04
Signaling by Insulin receptor	59	9.22e-05	0.294000	5.42e-04
Influenza Infection	154	9.35e-05	-0.182000	5.48e-04
Advanced glycosylation endproduct receptor signaling	12	9.45e-05	0.651000	5.51e-04
Telomere C-strand (Lagging Strand) Synthesis	34	9.52e-05	-0.387000	5.53e-04
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	11	9.66e-05	0.679000	5.59e-04
Unwinding of DNA	12	1.04e-04	-0.647000	5.98e-04
Ubiquitin-dependent degradation of Cyclin D	51	1.07e-04	0.313000	6.14e-04
Signaling by EGFR	46	1.08e-04	0.330000	6.18e-04
Amino acids regulate mTORC1	50	1.10e-04	0.316000	6.24e-04
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	22	1.10e-04	0.476000	6.24e-04
Negative regulation of MET activity	18	1.12e-04	0.526000	6.34e-04
Uptake and function of anthrax toxins	10	1.13e-04	0.705000	6.34e-04
Hedgehog 'on' state	76	1.13e-04	0.256000	6.34e-04
Response of EIF2AK4 (GCN2) to amino acid deficiency	100	1.14e-04	-0.223000	6.36e-04
Extension of Telomeres	51	1.15e-04	-0.312000	6.36e-04
tRNA processing in the nucleus	59	1.20e-04	-0.290000	6.60e-04
Signaling by NOTCH1	67	1.22e-04	0.271000	6.68e-04
Estrogen-dependent gene expression	99	1.25e-04	0.223000	6.83e-04
Ion channel transport	135	1.30e-04	0.191000	7.08e-04
Platelet sensitization by LDL	16	1.33e-04	0.552000	7.25e-04
p130Cas linkage to MAPK signaling for integrins	11	1.39e-04	0.663000	7.50e-04
Integrin signaling	22	1.39e-04	0.469000	7.50e-04
Collagen degradation	28	1.40e-04	0.416000	7.50e-04
Autodegradation of Cdh1 by Cdh1:APC/C	64	1.44e-04	0.275000	7.72e-04
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	24	1.52e-04	-0.447000	8.08e-04
Diseases of programmed cell death	23	1.53e-04	0.456000	8.12e-04
Transcriptional regulation of white adipocyte differentiation	77	1.54e-04	0.249000	8.13e-04
MTOR signalling	38	1.59e-04	0.354000	8.35e-04
Notch-HLH transcription pathway	28	1.72e-04	0.410000	9.03e-04
RHO GTPases activate PAKs	20	1.79e-04	0.484000	9.33e-04
Interferon alpha/beta signaling	57	1.86e-04	-0.286000	9.67e-04
Sealing of the nuclear envelope (NE) by ESCRT-III	25	1.87e-04	0.432000	9.72e-04
Recycling pathway of L1	26	1.89e-04	0.423000	9.77e-04
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	73	1.92e-04	0.252000	9.90e-04
Response of Mtb to phagocytosis	22	1.94e-04	0.459000	9.93e-04
Fanconi Anemia Pathway	36	2.19e-04	-0.356000	1.12e-03
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	30	2.21e-04	0.390000	1.12e-03
Hyaluronan metabolism	15	2.23e-04	0.550000	1.13e-03
Resolution of Abasic Sites (AP sites)	37	2.42e-04	-0.349000	1.22e-03
Autodegradation of the E3 ubiquitin ligase COP1	50	2.66e-04	0.298000	1.34e-03
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	114	2.77e-04	-0.197000	1.39e-03
Nonsense-Mediated Decay (NMD)	114	2.77e-04	-0.197000	1.39e-03
SCF-beta-TrCP mediated degradation of Emi1	54	2.84e-04	0.285000	1.41e-03
MHC class II antigen presentation	101	2.86e-04	0.209000	1.42e-03
ABC-family proteins mediated transport	94	2.90e-04	0.216000	1.43e-03
APC/C:Cdc20 mediated degradation of Securin	67	2.91e-04	0.256000	1.44e-03
Formation of a pool of free 40S subunits	100	2.96e-04	-0.209000	1.45e-03
UCH proteinases	87	3.07e-04	0.224000	1.50e-03
Downstream signaling events of B Cell Receptor (BCR)	80	3.08e-04	0.233000	1.50e-03
Chaperonin-mediated protein folding	84	3.15e-04	0.227000	1.53e-03
Interferon Signaling	177	3.18e-04	-0.157000	1.54e-03
RAF activation	32	3.61e-04	0.364000	1.73e-03
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	51	3.62e-04	0.289000	1.73e-03
Presynaptic phase of homologous DNA pairing and strand exchange	39	3.62e-04	-0.330000	1.73e-03
Metabolism of steroids	120	3.63e-04	0.188000	1.73e-03
Golgi Cisternae Pericentriolar Stack Reorganization	14	3.75e-04	0.549000	1.78e-03
TP53 Regulates Metabolic Genes	85	3.84e-04	0.223000	1.82e-03
Inhibition of DNA recombination at telomere	35	4.03e-04	0.346000	1.90e-03
COPI-dependent Golgi-to-ER retrograde traffic	78	4.15e-04	0.231000	1.95e-03
Lagging Strand Synthesis	20	4.38e-04	-0.454000	2.05e-03
Transcriptional regulation by RUNX1	185	4.57e-04	0.149000	2.13e-03
Packaging Of Telomere Ends	20	4.67e-04	0.452000	2.18e-03
Degradation of the extracellular matrix	78	4.70e-04	0.229000	2.18e-03
Adaptive Immune System	757	4.84e-04	0.074500	2.24e-03
G-protein beta:gamma signalling	29	5.02e-04	0.373000	2.31e-03
Degradation of AXIN	54	5.06e-04	0.274000	2.32e-03
Energy dependent regulation of mTOR by LKB1-AMPK	27	5.19e-04	0.386000	2.38e-03
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	76	5.23e-04	0.230000	2.39e-03
GRB2:SOS provides linkage to MAPK signaling for Integrins	12	5.27e-04	0.578000	2.40e-03
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases	13	5.33e-04	0.555000	2.41e-03
Interactions of Rev with host cellular proteins	37	5.34e-04	-0.329000	2.41e-03
Regulation of actin dynamics for phagocytic cup formation	123	5.35e-04	0.181000	2.41e-03
Rev-mediated nuclear export of HIV RNA	35	5.73e-04	-0.336000	2.57e-03
Stabilization of p53	55	5.81e-04	0.268000	2.60e-03
Regulation of insulin secretion	60	5.84e-04	0.257000	2.60e-03
Extra-nuclear estrogen signaling	66	5.87e-04	0.245000	2.61e-03
activated TAK1 mediates p38 MAPK activation	19	6.06e-04	0.454000	2.69e-03
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	73	6.13e-04	0.232000	2.70e-03
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	72	6.39e-04	0.233000	2.81e-03
APC/C:Cdc20 mediated degradation of mitotic proteins	75	6.49e-04	0.228000	2.85e-03
CDK-mediated phosphorylation and removal of Cdc6	72	6.56e-04	0.232000	2.87e-03
Fcgamma receptor (FCGR) dependent phagocytosis	147	6.62e-04	0.163000	2.89e-03
Fc epsilon receptor (FCERI) signaling	191	6.72e-04	0.143000	2.92e-03
Retrograde neurotrophin signalling	12	6.74e-04	0.567000	2.92e-03
Sphingolipid metabolism	77	6.76e-04	0.224000	2.92e-03
Regulation of RAS by GAPs	67	6.80e-04	0.240000	2.93e-03
Transcriptional regulation by RUNX3	90	6.83e-04	0.207000	2.93e-03
Signal transduction by L1	20	7.32e-04	0.436000	3.13e-03
Dissolution of Fibrin Clot	12	7.34e-04	0.563000	3.13e-03
MAPK targets/ Nuclear events mediated by MAP kinases	31	7.39e-04	0.350000	3.14e-03
TBC/RABGAPs	45	7.53e-04	0.290000	3.19e-03
NS1 Mediated Effects on Host Pathways	40	7.65e-04	-0.307000	3.23e-03
Protein folding	90	7.72e-04	0.205000	3.25e-03
Signaling by Non-Receptor Tyrosine Kinases	48	8.02e-04	0.280000	3.35e-03
Signaling by PTK6	48	8.02e-04	0.280000	3.35e-03
PCNA-Dependent Long Patch Base Excision Repair	21	8.10e-04	-0.422000	3.38e-03
Plasma lipoprotein assembly, remodeling, and clearance	53	8.44e-04	0.265000	3.51e-03
Factors involved in megakaryocyte development and platelet production	117	8.63e-04	0.178000	3.58e-03
p75 NTR receptor-mediated signalling	89	8.77e-04	0.204000	3.62e-03
Asymmetric localization of PCP proteins	61	8.97e-04	0.246000	3.70e-03
Costimulation by the CD28 family	74	9.12e-04	-0.223000	3.75e-03
HDR through Homologous Recombination (HRR)	66	9.26e-04	-0.236000	3.79e-03
ERK/MAPK targets	22	9.27e-04	0.408000	3.79e-03
Neuronal System	259	9.55e-04	0.119000	3.89e-03
Semaphorin interactions	57	9.69e-04	0.253000	3.93e-03
XBP1(S) activates chaperone genes	47	9.85e-04	0.278000	3.99e-03
DARPP-32 events	22	9.93e-04	0.405000	4.01e-03
Transmission across Chemical Synapses	172	1.04e-03	0.145000	4.20e-03
Spry regulation of FGF signaling	16	1.07e-03	0.472000	4.28e-03
HIV Infection	225	1.07e-03	0.127000	4.30e-03
SCF(Skp2)-mediated degradation of p27/p21	60	1.08e-03	0.244000	4.31e-03
Fatty acid metabolism	153	1.09e-03	0.153000	4.33e-03
Signaling by Hedgehog	121	1.17e-03	0.171000	4.63e-03
Gap junction trafficking	14	1.20e-03	0.500000	4.76e-03
IRE1alpha activates chaperones	49	1.21e-03	0.267000	4.77e-03
NOTCH1 Intracellular Domain Regulates Transcription	45	1.21e-03	0.279000	4.77e-03
Growth hormone receptor signaling	20	1.22e-03	0.418000	4.77e-03
Metabolism of non-coding RNA	53	1.23e-03	-0.257000	4.77e-03
snRNP Assembly	53	1.23e-03	-0.257000	4.77e-03
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	53	1.23e-03	0.257000	4.77e-03
CDT1 association with the CDC6:ORC:origin complex	58	1.26e-03	0.245000	4.87e-03
Complex I biogenesis	55	1.31e-03	0.250000	5.06e-03
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	35	1.33e-03	0.313000	5.14e-03
Calnexin/calreticulin cycle	26	1.36e-03	0.363000	5.23e-03
ADP signalling through P2Y purinoceptor 1	21	1.41e-03	0.402000	5.40e-03
Signaling by Erythropoietin	24	1.44e-03	0.376000	5.49e-03
Neurotransmitter receptors and postsynaptic signal transmission	124	1.45e-03	0.166000	5.53e-03
Antigen processing: Ubiquitination & Proteasome degradation	289	1.48e-03	0.109000	5.63e-03
Transcriptional regulation by RUNX2	103	1.48e-03	0.181000	5.63e-03
GPVI-mediated activation cascade	31	1.52e-03	0.329000	5.73e-03
Cell surface interactions at the vascular wall	174	1.52e-03	0.139000	5.73e-03
Thrombin signalling through proteinase activated receptors (PARs)	27	1.53e-03	0.352000	5.76e-03
NEP/NS2 Interacts with the Cellular Export Machinery	32	1.56e-03	-0.323000	5.85e-03
Rho GTPase cycle	126	1.60e-03	0.163000	5.99e-03
Regulation of cholesterol biosynthesis by SREBP (SREBF)	55	1.62e-03	0.246000	6.02e-03
InlB-mediated entry of Listeria monocytogenes into host cell	12	1.63e-03	0.525000	6.05e-03
Formation of ATP by chemiosmotic coupling	18	1.67e-03	0.428000	6.20e-03
Vpr-mediated nuclear import of PICs	34	1.72e-03	-0.311000	6.37e-03
Platelet Adhesion to exposed collagen	13	1.83e-03	0.499000	6.75e-03
Aquaporin-mediated transport	38	1.87e-03	0.292000	6.86e-03
Nuclear import of Rev protein	34	1.88e-03	-0.308000	6.91e-03
Inflammasomes	20	1.92e-03	0.401000	7.00e-03
Regulation of RUNX2 expression and activity	67	1.92e-03	0.219000	7.00e-03
Disorders of transmembrane transporters	148	1.94e-03	0.148000	7.05e-03
Signaling by Leptin	10	1.99e-03	0.565000	7.21e-03
G1/S DNA Damage Checkpoints	66	2.01e-03	0.220000	7.26e-03
mTORC1-mediated signalling	23	2.02e-03	0.372000	7.29e-03
Diseases of carbohydrate metabolism	29	2.03e-03	0.331000	7.29e-03
PLC beta mediated events	43	2.03e-03	0.272000	7.30e-03
Sema4D in semaphorin signaling	22	2.10e-03	0.379000	7.51e-03
p53-Dependent G1 DNA Damage Response	64	2.11e-03	0.222000	7.51e-03
p53-Dependent G1/S DNA damage checkpoint	64	2.11e-03	0.222000	7.51e-03
GAB1 signalosome	15	2.21e-03	0.456000	7.85e-03
VLDLR internalisation and degradation	12	2.22e-03	0.510000	7.88e-03
The NLRP3 inflammasome	15	2.27e-03	0.455000	8.01e-03
Pentose phosphate pathway	13	2.32e-03	0.488000	8.17e-03
tRNA modification in the nucleus and cytosol	43	2.34e-03	-0.268000	8.23e-03
TAK1 activates NFkB by phosphorylation and activation of IKKs complex	27	2.40e-03	0.337000	8.41e-03
Signaling by TGFB family members	91	2.40e-03	0.184000	8.41e-03
Cleavage of the damaged purine	24	2.47e-03	0.357000	8.56e-03
Depurination	24	2.47e-03	0.357000	8.56e-03
Recognition and association of DNA glycosylase with site containing an affected purine	24	2.47e-03	0.357000	8.56e-03
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	15	2.47e-03	0.451000	8.56e-03
Pre-NOTCH Processing in Golgi	18	2.56e-03	0.411000	8.82e-03
Interactions of Vpr with host cellular proteins	37	2.58e-03	-0.286000	8.88e-03
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	54	2.68e-03	0.236000	9.12e-03
Constitutive Signaling by NOTCH1 PEST Domain Mutants	54	2.68e-03	0.236000	9.12e-03
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	54	2.68e-03	0.236000	9.12e-03
Signaling by NOTCH1 PEST Domain Mutants in Cancer	54	2.68e-03	0.236000	9.12e-03
Signaling by NOTCH1 in Cancer	54	2.68e-03	0.236000	9.12e-03
Glycogen metabolism	23	2.70e-03	0.361000	9.17e-03
Formation of the cornified envelope	21	2.87e-03	0.376000	9.71e-03
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	22	2.90e-03	0.367000	9.78e-03
Glucagon signaling in metabolic regulation	27	2.92e-03	0.331000	9.85e-03
IKK complex recruitment mediated by RIP1	23	3.06e-03	0.357000	1.03e-02
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding	29	3.13e-03	0.317000	1.05e-02
Regulation of APC/C activators between G1/S and early anaphase	80	3.16e-03	0.191000	1.05e-02
Cell recruitment (pro-inflammatory response)	22	3.24e-03	0.363000	1.08e-02
Purinergic signaling in leishmaniasis infection	22	3.24e-03	0.363000	1.08e-02
FCGR3A-mediated phagocytosis	121	3.26e-03	0.155000	1.08e-02
Leishmania phagocytosis	121	3.26e-03	0.155000	1.08e-02
Parasite infection	121	3.26e-03	0.155000	1.08e-02
HDR through Single Strand Annealing (SSA)	37	3.31e-03	-0.279000	1.09e-02
Death Receptor Signalling	132	3.42e-03	0.148000	1.12e-02
Muscle contraction	142	3.45e-03	0.142000	1.13e-02
Vasopressin regulates renal water homeostasis via Aquaporins	34	3.47e-03	0.290000	1.14e-02
Signaling by GPCR	545	3.48e-03	0.073200	1.14e-02
G-protein mediated events	44	3.60e-03	0.254000	1.17e-02
Processive synthesis on the lagging strand	15	3.73e-03	-0.433000	1.21e-02
IRAK1 recruits IKK complex	10	3.75e-03	0.529000	1.21e-02
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	10	3.75e-03	0.529000	1.21e-02
Mitotic Anaphase	224	3.83e-03	0.112000	1.23e-02
Antiviral mechanism by IFN-stimulated genes	80	3.84e-03	-0.187000	1.24e-02
APC/C-mediated degradation of cell cycle proteins	87	3.88e-03	0.179000	1.24e-02
Regulation of mitotic cell cycle	87	3.88e-03	0.179000	1.24e-02
SARS-CoV-1 Infection	47	3.90e-03	0.243000	1.25e-02
Activation of Matrix Metalloproteinases	23	3.96e-03	0.347000	1.26e-02
MET activates RAP1 and RAC1	10	4.01e-03	0.525000	1.28e-02
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS)	12	4.10e-03	0.478000	1.30e-02
Diseases of hemostasis	12	4.10e-03	0.478000	1.30e-02
Collagen formation	66	4.13e-03	0.204000	1.30e-02
Thromboxane signalling through TP receptor	20	4.13e-03	0.370000	1.30e-02
Signaling by SCF-KIT	40	4.19e-03	0.262000	1.32e-02
Selective autophagy	58	4.23e-03	0.217000	1.33e-02
Signaling by TGF-beta Receptor Complex	72	4.25e-03	0.195000	1.33e-02
Condensation of Prophase Chromosomes	29	4.30e-03	0.306000	1.34e-02
NOTCH4 Activation and Transmission of Signal to the Nucleus	10	4.32e-03	0.521000	1.34e-02
Export of Viral Ribonucleoproteins from Nucleus	33	4.35e-03	-0.287000	1.35e-02
Plasma lipoprotein clearance	29	4.39e-03	0.306000	1.36e-02
Apoptotic execution phase	45	4.42e-03	0.245000	1.37e-02
SHC1 events in EGFR signaling	12	4.43e-03	0.474000	1.37e-02
Disassembly of the destruction complex and recruitment of AXIN to the membrane	29	4.48e-03	0.305000	1.38e-02
Signaling by EGFR in Cancer	23	4.50e-03	0.342000	1.38e-02
Trafficking of GluR2-containing AMPA receptors	12	4.59e-03	0.472000	1.41e-02
Sema4D induced cell migration and growth-cone collapse	19	4.60e-03	0.376000	1.41e-02
Transport of Ribonucleoproteins into the Host Nucleus	32	4.64e-03	-0.289000	1.42e-02
G alpha (z) signalling events	36	4.66e-03	0.272000	1.42e-02
Prolonged ERK activation events	13	4.85e-03	0.451000	1.47e-02
Transport of Mature mRNA Derived from an Intronless Transcript	42	4.85e-03	-0.251000	1.47e-02
Signaling by ERBB4	44	4.90e-03	0.245000	1.48e-02
WNT5A-dependent internalization of FZD4	13	5.11e-03	0.448000	1.54e-02
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	182	5.15e-03	-0.120000	1.55e-02
M Phase	361	5.15e-03	0.085700	1.55e-02
Assembly Of The HIV Virion	15	5.22e-03	0.416000	1.56e-02
Uptake and actions of bacterial toxins	27	5.22e-03	0.311000	1.56e-02
Transport of the SLBP independent Mature mRNA	35	5.34e-03	-0.272000	1.59e-02
GPCR downstream signalling	501	5.39e-03	0.072600	1.61e-02
Membrane binding and targetting of GAG proteins	13	5.44e-03	0.445000	1.61e-02
Synthesis And Processing Of GAG, GAGPOL Polyproteins	13	5.44e-03	0.445000	1.61e-02
Mitotic Metaphase and Anaphase	225	5.46e-03	0.107000	1.62e-02
LDL clearance	18	5.50e-03	0.378000	1.62e-02
Intraflagellar transport	39	5.71e-03	-0.256000	1.68e-02
AKT phosphorylates targets in the cytosol	14	5.96e-03	0.424000	1.75e-02
ADP signalling through P2Y purinoceptor 12	18	5.98e-03	0.374000	1.75e-02
Cyclin E associated events during G1/S transition	83	6.17e-03	0.174000	1.81e-02
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	36	6.24e-03	0.263000	1.82e-02
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	32	6.24e-03	0.279000	1.82e-02
Unfolded Protein Response (UPR)	87	6.30e-03	0.169000	1.83e-02
Stimuli-sensing channels	74	6.32e-03	0.184000	1.83e-02
Formation of Fibrin Clot (Clotting Cascade)	26	6.35e-03	0.309000	1.84e-02
Glycosaminoglycan metabolism	94	6.37e-03	0.163000	1.84e-02
Integrin cell surface interactions	52	6.43e-03	0.218000	1.85e-02
tRNA Aminoacylation	42	6.61e-03	-0.242000	1.90e-02
Transport of bile salts and organic acids, metal ions and amine compounds	55	6.67e-03	0.211000	1.91e-02
GRB2 events in EGFR signaling	11	6.79e-03	0.471000	1.94e-02
GTP hydrolysis and joining of the 60S ribosomal subunit	111	6.89e-03	-0.148000	1.97e-02
RHO GTPases activate CIT	18	6.98e-03	0.367000	1.99e-02
ERKs are inactivated	13	7.00e-03	0.432000	1.99e-02
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	11	7.01e-03	0.469000	1.99e-02
Mitochondrial biogenesis	88	7.03e-03	0.166000	1.99e-02
Polymerase switching on the C-strand of the telomere	26	7.18e-03	-0.305000	2.03e-02
Activation of HOX genes during differentiation	69	7.31e-03	0.187000	2.06e-02
Activation of anterior HOX genes in hindbrain development during early embryogenesis	69	7.31e-03	0.187000	2.06e-02
G-protein activation	23	7.43e-03	0.322000	2.09e-02
Synthesis of PC	23	7.57e-03	0.322000	2.12e-02
TGF-beta receptor signaling activates SMADs	32	7.63e-03	0.273000	2.14e-02
Potential therapeutics for SARS	36	7.80e-03	0.256000	2.18e-02
Interleukin-12 family signaling	53	7.86e-03	0.211000	2.19e-02
GABA receptor activation	36	7.86e-03	0.256000	2.19e-02
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	32	7.94e-03	-0.271000	2.20e-02
Regulation of Glucokinase by Glucokinase Regulatory Protein	32	7.94e-03	-0.271000	2.20e-02
Gastrin-CREB signalling pathway via PKC and MAPK	14	8.03e-03	0.409000	2.22e-02
Activation of gene expression by SREBF (SREBP)	42	8.14e-03	0.236000	2.25e-02
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	80	8.16e-03	0.171000	2.25e-02
Interleukin-10 signaling	35	8.52e-03	0.257000	2.34e-02
Syndecan interactions	19	8.61e-03	0.348000	2.36e-02
Suppression of phagosomal maturation	12	8.62e-03	0.438000	2.36e-02
ER Quality Control Compartment (ERQC)	21	8.78e-03	0.330000	2.39e-02
Caspase activation via extrinsic apoptotic signalling pathway	25	8.79e-03	0.303000	2.39e-02
Transport of Mature mRNAs Derived from Intronless Transcripts	43	8.79e-03	-0.231000	2.39e-02
Removal of the Flap Intermediate	14	8.85e-03	-0.404000	2.40e-02
L13a-mediated translational silencing of Ceruloplasmin expression	110	8.88e-03	-0.144000	2.41e-02
Beta-catenin phosphorylation cascade	17	9.00e-03	0.366000	2.44e-02
Signaling by FGFR3	31	9.03e-03	0.271000	2.44e-02
Formation of the beta-catenin:TCF transactivating complex	46	9.07e-03	0.222000	2.44e-02
Glycogen breakdown (glycogenolysis)	13	9.17e-03	0.417000	2.47e-02
Erythropoietin activates RAS	13	9.25e-03	0.417000	2.48e-02
TNFR2 non-canonical NF-kB pathway	96	9.35e-03	0.153000	2.50e-02
Effects of PIP2 hydrolysis	24	9.50e-03	-0.306000	2.54e-02
Hedgehog 'off' state	93	9.50e-03	0.156000	2.54e-02
MET promotes cell motility	26	9.58e-03	0.294000	2.54e-02
Cleavage of the damaged pyrimidine	29	9.60e-03	0.278000	2.54e-02
Depyrimidination	29	9.60e-03	0.278000	2.54e-02
Recognition and association of DNA glycosylase with site containing an affected pyrimidine	29	9.60e-03	0.278000	2.54e-02
Intra-Golgi traffic	43	9.70e-03	0.228000	2.56e-02
EPH-ephrin mediated repulsion of cells	40	9.79e-03	0.236000	2.58e-02
Interleukin-3, Interleukin-5 and GM-CSF signaling	40	9.80e-03	0.236000	2.58e-02
Activation of GABAB receptors	31	9.83e-03	0.268000	2.58e-02
GABA B receptor activation	31	9.83e-03	0.268000	2.58e-02
G alpha (i) signalling events	246	9.90e-03	0.095500	2.59e-02
Josephin domain DUBs	10	9.94e-03	0.471000	2.60e-02
Mucopolysaccharidoses	11	9.95e-03	0.449000	2.60e-02
Negative regulation of FGFR3 signaling	20	1.00e-02	0.332000	2.62e-02
Transport of the SLBP Dependant Mature mRNA	36	1.02e-02	-0.247000	2.66e-02
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	36	1.04e-02	0.247000	2.71e-02
Endogenous sterols	17	1.05e-02	0.358000	2.72e-02
Assembly of the pre-replicative complex	67	1.07e-02	0.180000	2.77e-02
Biotin transport and metabolism	11	1.07e-02	-0.444000	2.77e-02
Regulation of IFNG signaling	14	1.11e-02	0.392000	2.84e-02
Signaling by NOTCH3	43	1.11e-02	0.224000	2.84e-02
Prefoldin mediated transfer of substrate to CCT/TriC	26	1.11e-02	0.288000	2.84e-02
Cristae formation	31	1.11e-02	0.263000	2.85e-02
G beta:gamma signalling through CDC42	17	1.12e-02	0.355000	2.86e-02
Negative regulation of FGFR1 signaling	24	1.14e-02	0.298000	2.92e-02
Glycogen synthesis	13	1.15e-02	0.405000	2.92e-02
MAP3K8 (TPL2)-dependent MAPK1/3 activation	16	1.15e-02	0.365000	2.92e-02
Gap junction trafficking and regulation	16	1.15e-02	0.365000	2.93e-02
HCMV Infection	96	1.17e-02	0.149000	2.97e-02
Protein localization	157	1.19e-02	0.116000	3.00e-02
TRAF6-mediated induction of TAK1 complex within TLR4 complex	16	1.20e-02	0.363000	3.03e-02
Cyclin A:Cdk2-associated events at S phase entry	85	1.20e-02	0.158000	3.03e-02
Pyruvate metabolism and Citric Acid (TCA) cycle	52	1.23e-02	0.201000	3.09e-02
Alpha-protein kinase 1 signaling pathway	11	1.24e-02	0.435000	3.11e-02
Nucleotide salvage	21	1.26e-02	0.315000	3.14e-02
Cap-dependent Translation Initiation	118	1.26e-02	-0.133000	3.14e-02
Eukaryotic Translation Initiation	118	1.26e-02	-0.133000	3.14e-02
Metabolism of porphyrins	22	1.26e-02	0.307000	3.15e-02
ATF6 (ATF6-alpha) activates chaperones	12	1.27e-02	0.416000	3.15e-02
Signaling by FGFR4	31	1.35e-02	0.256000	3.34e-02
Metabolism of steroid hormones	21	1.35e-02	0.311000	3.35e-02
RHO GTPases activate IQGAPs	11	1.36e-02	0.430000	3.35e-02
Base-Excision Repair, AP Site Formation	31	1.37e-02	0.256000	3.37e-02
Signal regulatory protein family interactions	12	1.38e-02	0.411000	3.39e-02
Glycosphingolipid metabolism	36	1.38e-02	0.237000	3.39e-02
Negative regulation of FGFR4 signaling	21	1.39e-02	0.310000	3.41e-02
SRP-dependent cotranslational protein targeting to membrane	111	1.39e-02	-0.135000	3.41e-02
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	22	1.40e-02	0.303000	3.43e-02
SUMOylation of DNA damage response and repair proteins	77	1.42e-02	-0.162000	3.45e-02
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	11	1.42e-02	0.427000	3.45e-02
VxPx cargo-targeting to cilium	19	1.42e-02	0.325000	3.45e-02
Common Pathway of Fibrin Clot Formation	14	1.42e-02	0.378000	3.45e-02
Circadian Clock	67	1.43e-02	0.173000	3.46e-02
Mitochondrial tRNA aminoacylation	21	1.45e-02	-0.308000	3.50e-02
RNA Polymerase I Transcription Initiation	47	1.46e-02	-0.206000	3.52e-02
ATF6 (ATF6-alpha) activates chaperone genes	10	1.47e-02	0.446000	3.53e-02
DNA Repair	289	1.49e-02	-0.083200	3.59e-02
FCERI mediated NF-kB activation	138	1.54e-02	0.119000	3.70e-02
G alpha (12/13) signalling events	69	1.59e-02	0.168000	3.79e-02
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	32	1.59e-02	0.246000	3.79e-02
HCMV Late Events	69	1.60e-02	0.168000	3.81e-02
CD28 dependent PI3K/Akt signaling	22	1.60e-02	-0.297000	3.81e-02
G beta:gamma signalling through PLC beta	17	1.61e-02	0.337000	3.82e-02
SIRT1 negatively regulates rRNA expression	24	1.62e-02	0.284000	3.85e-02
RNA Polymerase III Transcription Initiation From Type 1 Promoter	28	1.63e-02	-0.262000	3.88e-02
Cell-Cell communication	89	1.67e-02	0.147000	3.96e-02
Activated NOTCH1 Transmits Signal to the Nucleus	27	1.69e-02	0.266000	3.99e-02
Interleukin-12 signaling	44	1.71e-02	0.208000	4.04e-02
Cell-extracellular matrix interactions	14	1.73e-02	0.367000	4.07e-02
Regulated proteolysis of p75NTR	11	1.74e-02	0.414000	4.08e-02
NGF-stimulated transcription	31	1.74e-02	0.247000	4.08e-02
Leading Strand Synthesis	14	1.75e-02	-0.367000	4.09e-02
Polymerase switching	14	1.75e-02	-0.367000	4.09e-02
Postmitotic nuclear pore complex (NPC) reformation	27	1.76e-02	-0.264000	4.11e-02
SLC-mediated transmembrane transport	180	1.76e-02	0.103000	4.11e-02
Cilium Assembly	181	1.77e-02	-0.102000	4.12e-02
Response of EIF2AK1 (HRI) to heme deficiency	14	1.77e-02	0.366000	4.12e-02
Peroxisomal protein import	57	1.78e-02	0.181000	4.13e-02
Cell junction organization	60	1.79e-02	0.177000	4.16e-02
SUMOylation of immune response proteins	11	1.81e-02	0.412000	4.18e-02
HDR through MMEJ (alt-NHEJ)	10	1.86e-02	-0.430000	4.30e-02
Sphingolipid de novo biosynthesis	41	1.89e-02	0.212000	4.36e-02
Keratinization	33	1.96e-02	0.235000	4.50e-02
Formation of tubulin folding intermediates by CCT/TriC	22	1.97e-02	0.287000	4.53e-02
Translation of Replicase and Assembly of the Replication Transcription Complex	12	2.00e-02	0.388000	4.58e-02
Interferon gamma signaling	83	2.00e-02	-0.148000	4.58e-02
Ca-dependent events	29	2.06e-02	0.248000	4.70e-02
Butyrophilin (BTN) family interactions	10	2.07e-02	-0.423000	4.71e-02
G beta:gamma signalling through PI3Kgamma	22	2.10e-02	0.284000	4.79e-02
Activation of G protein gated Potassium channels	20	2.12e-02	0.298000	4.79e-02
G protein gated Potassium channels	20	2.12e-02	0.298000	4.79e-02
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	20	2.12e-02	0.298000	4.79e-02
Regulation of PTEN gene transcription	59	2.13e-02	0.173000	4.82e-02
Apoptotic factor-mediated response	18	2.15e-02	0.313000	4.86e-02
FOXO-mediated transcription of cell death genes	16	2.16e-02	0.332000	4.88e-02
RORA activates gene expression	18	2.24e-02	0.311000	5.03e-02
Transport of Mature mRNA derived from an Intron-Containing Transcript	72	2.24e-02	-0.156000	5.04e-02
Nucleobase catabolism	28	2.31e-02	0.248000	5.18e-02
TRAF6 mediated NF-kB activation	23	2.36e-02	0.273000	5.28e-02
RHO GTPases activate KTN1	11	2.38e-02	0.394000	5.32e-02
RNA Polymerase III Transcription Initiation From Type 2 Promoter	27	2.40e-02	-0.251000	5.36e-02
Presynaptic function of Kainate receptors	18	2.45e-02	0.306000	5.45e-02
ISG15 antiviral mechanism	72	2.46e-02	-0.153000	5.46e-02
Pyruvate metabolism	28	2.46e-02	0.245000	5.46e-02
Oncogene Induced Senescence	33	2.48e-02	0.226000	5.51e-02
Telomere C-strand synthesis initiation	13	2.51e-02	-0.359000	5.55e-02
PKA activation in glucagon signalling	14	2.54e-02	0.345000	5.61e-02
Regulation of TP53 Activity	152	2.55e-02	-0.105000	5.62e-02
HuR (ELAVL1) binds and stabilizes mRNA	10	2.60e-02	0.407000	5.73e-02
Negative regulation of the PI3K/AKT network	87	2.61e-02	0.138000	5.75e-02
Arachidonic acid metabolism	43	2.66e-02	0.195000	5.84e-02
Gluconeogenesis	28	2.70e-02	0.242000	5.91e-02
DNA Damage/Telomere Stress Induced Senescence	44	2.74e-02	0.192000	6.00e-02
O-glycosylation of TSR domain-containing proteins	27	2.75e-02	-0.245000	6.00e-02
Formation of apoptosome	11	2.75e-02	0.384000	6.00e-02
Regulation of the apoptosome activity	11	2.75e-02	0.384000	6.00e-02
NOD1/2 Signaling Pathway	32	2.78e-02	0.225000	6.05e-02
Triglyceride catabolism	16	2.79e-02	0.318000	6.05e-02
Interleukin-6 signaling	10	2.91e-02	0.398000	6.32e-02
SUMOylation of SUMOylation proteins	35	2.93e-02	-0.213000	6.35e-02
Heme degradation	10	2.97e-02	0.397000	6.43e-02
Myogenesis	21	2.98e-02	0.274000	6.43e-02
Diseases associated with O-glycosylation of proteins	49	3.02e-02	-0.179000	6.50e-02
Nucleobase biosynthesis	13	3.03e-02	-0.347000	6.52e-02
Citric acid cycle (TCA cycle)	22	3.04e-02	0.267000	6.52e-02
Frs2-mediated activation	11	3.04e-02	0.377000	6.52e-02
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	26	3.05e-02	-0.245000	6.53e-02
NOTCH3 Activation and Transmission of Signal to the Nucleus	23	3.06e-02	0.260000	6.55e-02
Cell death signalling via NRAGE, NRIF and NADE	70	3.09e-02	0.149000	6.59e-02
Activation of the AP-1 family of transcription factors	10	3.10e-02	0.394000	6.61e-02
Diseases associated with glycosylation precursor biosynthesis	18	3.11e-02	0.293000	6.63e-02
SUMOylation of RNA binding proteins	47	3.20e-02	-0.181000	6.79e-02
Signalling to RAS	19	3.23e-02	0.284000	6.86e-02
G beta:gamma signalling through BTK	15	3.29e-02	0.318000	6.97e-02
Negative regulation of MAPK pathway	42	3.32e-02	0.190000	7.02e-02
Cytochrome c-mediated apoptotic response	13	3.32e-02	0.341000	7.02e-02
Retrograde transport at the Trans-Golgi-Network	49	3.38e-02	0.175000	7.13e-02
Transport of Mature Transcript to Cytoplasm	81	3.40e-02	-0.136000	7.14e-02
Apoptosis induced DNA fragmentation	10	3.40e-02	0.387000	7.14e-02
NR1H2 and NR1H3-mediated signaling	39	3.40e-02	0.196000	7.14e-02
Transcriptional Regulation by E2F6	34	3.41e-02	-0.210000	7.15e-02
Metalloprotease DUBs	21	3.43e-02	0.267000	7.18e-02
Signaling by FGFR1	38	3.46e-02	0.198000	7.22e-02
Signaling by the B Cell Receptor (BCR)	163	3.46e-02	0.095900	7.22e-02
Post-chaperonin tubulin folding pathway	19	3.49e-02	0.280000	7.27e-02
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	16	3.55e-02	0.304000	7.39e-02
The role of Nef in HIV-1 replication and disease pathogenesis	28	3.60e-02	0.229000	7.48e-02
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon	17	3.62e-02	0.293000	7.50e-02
DAP12 interactions	39	3.67e-02	0.193000	7.60e-02
DNA Double-Strand Break Repair	135	3.73e-02	-0.104000	7.70e-02
Activation of BAD and translocation to mitochondria	15	3.80e-02	0.309000	7.84e-02
Translesion synthesis by REV1	16	3.85e-02	-0.299000	7.93e-02
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	18	3.91e-02	0.281000	8.03e-02
Signaling by Ligand-Responsive EGFR Variants in Cancer	18	3.91e-02	0.281000	8.03e-02
Peptide hormone metabolism	50	3.92e-02	0.169000	8.04e-02
Termination of translesion DNA synthesis	32	3.96e-02	-0.210000	8.10e-02
Pexophagy	11	3.97e-02	0.358000	8.12e-02
Separation of Sister Chromatids	168	3.97e-02	0.092000	8.12e-02
Rap1 signalling	13	4.20e-02	0.326000	8.56e-02
Nuclear signaling by ERBB4	24	4.24e-02	0.239000	8.63e-02
Metabolism of Angiotensinogen to Angiotensins	11	4.29e-02	0.353000	8.73e-02
Meiotic synapsis	45	4.32e-02	0.174000	8.76e-02
Biosynthesis of specialized proresolving mediators (SPMs)	16	4.33e-02	0.292000	8.78e-02
Acyl chain remodelling of PC	19	4.38e-02	0.267000	8.86e-02
Intrinsic Pathway for Apoptosis	53	4.38e-02	0.160000	8.86e-02
Diseases of DNA repair	10	4.46e-02	-0.367000	9.00e-02
Defects in vitamin and cofactor metabolism	21	4.50e-02	-0.253000	9.05e-02
Mitotic Prophase	98	4.50e-02	0.117000	9.05e-02
Acyl chain remodelling of PI	10	4.53e-02	0.366000	9.09e-02
Elastic fibre formation	32	4.59e-02	0.204000	9.20e-02
HDMs demethylate histones	22	4.61e-02	0.246000	9.24e-02
RNA Polymerase II Pre-transcription Events	78	4.70e-02	0.130000	9.39e-02
Surfactant metabolism	22	4.72e-02	0.244000	9.42e-02
SHC1 events in ERBB2 signaling	17	4.72e-02	0.278000	9.42e-02
Mitotic G2-G2/M phases	183	4.73e-02	0.085000	9.42e-02
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	14	4.79e-02	-0.305000	9.52e-02
Aggrephagy	22	4.86e-02	0.243000	9.65e-02
p75NTR signals via NF-kB	15	4.92e-02	0.293000	9.76e-02
Defective B3GALTL causes Peters-plus syndrome (PpS)	26	5.02e-02	-0.222000	9.94e-02
Formation of RNA Pol II elongation complex	57	5.05e-02	0.150000	9.96e-02
RNA Polymerase II Transcription Elongation	57	5.05e-02	0.150000	9.96e-02
Biological oxidations	138	5.05e-02	0.096400	9.96e-02
Gap-filling DNA repair synthesis and ligation in GG-NER	25	5.14e-02	-0.225000	1.01e-01
MET activates RAS signaling	10	5.14e-02	0.356000	1.01e-01
SUMOylation of ubiquitinylation proteins	39	5.17e-02	-0.180000	1.01e-01
RET signaling	32	5.18e-02	0.199000	1.01e-01
Nuclear Pore Complex (NPC) Disassembly	36	5.20e-02	-0.187000	1.02e-01
Laminin interactions	21	5.27e-02	0.244000	1.03e-01
GP1b-IX-V activation signalling	10	5.30e-02	0.353000	1.03e-01
Misspliced GSK3beta mutants stabilize beta-catenin	15	5.33e-02	0.288000	1.03e-01
S33 mutants of beta-catenin aren't phosphorylated	15	5.33e-02	0.288000	1.03e-01
S37 mutants of beta-catenin aren't phosphorylated	15	5.33e-02	0.288000	1.03e-01
S45 mutants of beta-catenin aren't phosphorylated	15	5.33e-02	0.288000	1.03e-01
T41 mutants of beta-catenin aren't phosphorylated	15	5.33e-02	0.288000	1.03e-01
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex	15	5.33e-02	0.288000	1.03e-01
Processive synthesis on the C-strand of the telomere	19	5.46e-02	-0.255000	1.05e-01
Chemokine receptors bind chemokines	39	5.55e-02	-0.177000	1.07e-01
Initiation of Nuclear Envelope (NE) Reformation	19	5.57e-02	0.254000	1.07e-01
Sialic acid metabolism	28	5.59e-02	0.209000	1.07e-01
Chromosome Maintenance	105	5.59e-02	-0.108000	1.07e-01
NoRC negatively regulates rRNA expression	62	5.63e-02	0.140000	1.08e-01
cGMP effects	13	5.75e-02	0.304000	1.10e-01
Striated Muscle Contraction	24	5.77e-02	0.224000	1.10e-01
TNFR1-induced proapoptotic signaling	12	5.80e-02	-0.316000	1.11e-01
Metabolism of fat-soluble vitamins	28	5.81e-02	0.207000	1.11e-01
Signaling by ERBB2	44	5.82e-02	0.165000	1.11e-01
Translesion synthesis by POLI	17	5.83e-02	-0.265000	1.11e-01
Synthesis of Leukotrienes (LT) and Eoxins (EX)	15	5.85e-02	0.282000	1.11e-01
Assembly of collagen fibrils and other multimeric structures	42	5.85e-02	0.169000	1.11e-01
Regulation of signaling by CBL	18	5.86e-02	0.257000	1.11e-01
Glycogen storage diseases	13	5.87e-02	0.303000	1.11e-01
Trafficking and processing of endosomal TLR	13	5.96e-02	0.302000	1.13e-01
Constitutive Signaling by EGFRvIII	14	6.00e-02	0.290000	1.13e-01
Signaling by EGFRvIII in Cancer	14	6.00e-02	0.290000	1.13e-01
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	33	6.02e-02	0.189000	1.13e-01
Regulation of TP53 Activity through Acetylation	29	6.19e-02	-0.200000	1.16e-01
TICAM1, RIP1-mediated IKK complex recruitment	19	6.20e-02	0.247000	1.16e-01
Orc1 removal from chromatin	70	6.24e-02	0.129000	1.17e-01
Pyrimidine salvage	10	6.27e-02	0.340000	1.17e-01
Dual Incision in GG-NER	41	6.34e-02	-0.168000	1.18e-01
p38MAPK events	13	6.44e-02	0.296000	1.20e-01
Intrinsic Pathway of Fibrin Clot Formation	16	6.51e-02	0.266000	1.21e-01
SUMOylation of chromatin organization proteins	57	6.53e-02	-0.141000	1.22e-01
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	13	6.69e-02	0.294000	1.24e-01
Downregulation of ERBB2 signaling	24	6.87e-02	0.215000	1.28e-01
Collagen biosynthesis and modifying enzymes	48	6.88e-02	0.152000	1.28e-01
SHC1 events in ERBB4 signaling	10	6.97e-02	0.331000	1.29e-01
PRC2 methylates histones and DNA	29	7.03e-02	0.194000	1.30e-01
RNA Polymerase III Transcription Initiation	36	7.09e-02	-0.174000	1.30e-01
G2/M Transition	181	7.10e-02	0.077800	1.30e-01
CaM pathway	27	7.10e-02	0.201000	1.30e-01
Calmodulin induced events	27	7.10e-02	0.201000	1.30e-01
Resolution of D-Loop Structures	33	7.17e-02	-0.181000	1.32e-01
Tie2 Signaling	16	7.32e-02	0.259000	1.34e-01
PKA activation	15	7.33e-02	0.267000	1.34e-01
Prostacyclin signalling through prostacyclin receptor	16	7.42e-02	0.258000	1.36e-01
FGFR1 mutant receptor activation	24	7.42e-02	0.210000	1.36e-01
SUMOylation of intracellular receptors	26	7.54e-02	0.201000	1.37e-01
BMAL1:CLOCK,NPAS2 activates circadian gene expression	25	7.62e-02	0.205000	1.39e-01
Caspase activation via Death Receptors in the presence of ligand	16	7.63e-02	0.256000	1.39e-01
Apoptotic cleavage of cellular proteins	34	7.73e-02	0.175000	1.40e-01
Retinoid metabolism and transport	24	7.73e-02	0.208000	1.40e-01
Metabolism of nucleotides	86	7.81e-02	0.110000	1.42e-01
EPHA-mediated growth cone collapse	13	7.87e-02	0.282000	1.42e-01
Signaling by cytosolic FGFR1 fusion mutants	18	7.90e-02	0.239000	1.43e-01
Chondroitin sulfate biosynthesis	12	7.95e-02	0.292000	1.44e-01
Translesion synthesis by POLK	17	7.97e-02	-0.245000	1.44e-01
Attenuation phase	23	8.14e-02	0.210000	1.46e-01
Potassium Channels	64	8.16e-02	0.126000	1.46e-01
Resolution of D-loop Structures through Holliday Junction Intermediates	32	8.16e-02	-0.178000	1.46e-01
Insulin receptor signalling cascade	39	8.17e-02	0.161000	1.46e-01
Inwardly rectifying K+ channels	24	8.21e-02	0.205000	1.47e-01
Transcriptional Regulation by MECP2	47	8.24e-02	0.146000	1.47e-01
Signaling by ERBB2 in Cancer	21	8.32e-02	0.218000	1.48e-01
Negative regulation of FGFR2 signaling	23	8.38e-02	0.208000	1.49e-01
ERBB2 Regulates Cell Motility	10	8.42e-02	0.315000	1.50e-01
Signaling by Hippo	18	8.45e-02	0.235000	1.50e-01
B-WICH complex positively regulates rRNA expression	47	8.49e-02	0.145000	1.51e-01
G alpha (q) signalling events	134	8.57e-02	0.086000	1.52e-01
Downregulation of TGF-beta receptor signaling	26	8.58e-02	0.195000	1.52e-01
PI Metabolism	80	8.62e-02	0.111000	1.52e-01
Listeria monocytogenes entry into host cells	17	8.67e-02	0.240000	1.53e-01
Mitotic Telophase/Cytokinesis	13	8.70e-02	0.274000	1.53e-01
Signaling by PDGFRA extracellular domain mutants	12	8.72e-02	0.285000	1.53e-01
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants	12	8.72e-02	0.285000	1.53e-01
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	18	8.92e-02	0.231000	1.57e-01
NOTCH3 Intracellular Domain Regulates Transcription	21	9.00e-02	0.214000	1.58e-01
SUMOylation of DNA replication proteins	46	9.00e-02	-0.144000	1.58e-01
Signaling by PDGF	44	9.05e-02	0.147000	1.58e-01
Acyl chain remodelling of PE	20	9.08e-02	0.218000	1.59e-01
RNA polymerase II transcribes snRNA genes	72	9.10e-02	0.115000	1.59e-01
Synthesis of PIPs at the plasma membrane	52	9.12e-02	0.135000	1.59e-01
Metabolism of nitric oxide: NOS3 activation and regulation	12	9.17e-02	0.281000	1.60e-01
Synthesis of substrates in N-glycan biosythesis	58	9.20e-02	0.128000	1.60e-01
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	16	9.23e-02	0.243000	1.60e-01
Translation	295	9.32e-02	-0.056800	1.62e-01
FCGR activation	76	9.51e-02	-0.111000	1.64e-01
AMER1 mutants destabilize the destruction complex	14	9.52e-02	0.258000	1.64e-01
APC truncation mutants have impaired AXIN binding	14	9.52e-02	0.258000	1.64e-01
AXIN missense mutants destabilize the destruction complex	14	9.52e-02	0.258000	1.64e-01
AXIN mutants destabilize the destruction complex, activating WNT signaling	14	9.52e-02	0.258000	1.64e-01
Truncations of AMER1 destabilize the destruction complex	14	9.52e-02	0.258000	1.64e-01
truncated APC mutants destabilize the destruction complex	14	9.52e-02	0.258000	1.64e-01
Glucose metabolism	84	9.53e-02	0.105000	1.64e-01
Nitric oxide stimulates guanylate cyclase	16	9.66e-02	0.240000	1.66e-01
Homology Directed Repair	110	9.69e-02	-0.091600	1.66e-01
Mitophagy	28	9.74e-02	0.181000	1.67e-01
Nuclear Envelope (NE) Reassembly	69	9.84e-02	0.115000	1.68e-01
ABC transporters in lipid homeostasis	14	9.87e-02	-0.255000	1.68e-01
FOXO-mediated transcription	59	9.92e-02	0.124000	1.69e-01
Receptor Mediated Mitophagy	11	1.01e-01	0.286000	1.71e-01
Chaperone Mediated Autophagy	20	1.01e-01	0.212000	1.71e-01
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	14	1.02e-01	-0.253000	1.73e-01
mRNA decay by 3' to 5' exoribonuclease	16	1.03e-01	-0.236000	1.74e-01
Triglyceride metabolism	25	1.03e-01	0.188000	1.75e-01
Insulin processing	21	1.05e-01	0.204000	1.77e-01
HIV Transcription Initiation	45	1.06e-01	0.139000	1.77e-01
RNA Polymerase II HIV Promoter Escape	45	1.06e-01	0.139000	1.77e-01
RNA Polymerase II Promoter Escape	45	1.06e-01	0.139000	1.77e-01
RNA Polymerase II Transcription Initiation	45	1.06e-01	0.139000	1.77e-01
RNA Polymerase II Transcription Initiation And Promoter Clearance	45	1.06e-01	0.139000	1.77e-01
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	45	1.06e-01	0.139000	1.77e-01
Signaling by FGFR1 in disease	31	1.06e-01	0.168000	1.78e-01
Mismatch Repair	15	1.06e-01	-0.241000	1.78e-01
Plasma lipoprotein remodeling	18	1.06e-01	0.220000	1.78e-01
Interleukin-27 signaling	11	1.09e-01	0.279000	1.82e-01
O-linked glycosylation of mucins	47	1.09e-01	0.135000	1.82e-01
Mitochondrial iron-sulfur cluster biogenesis	13	1.09e-01	0.257000	1.82e-01
NF-kB is activated and signals survival	12	1.10e-01	0.267000	1.83e-01
TICAM1,TRAF6-dependent induction of TAK1 complex	11	1.10e-01	0.278000	1.83e-01
Glutathione conjugation	26	1.11e-01	0.181000	1.84e-01
RNA Polymerase I Promoter Escape	47	1.11e-01	0.134000	1.85e-01
Recognition of DNA damage by PCNA-containing replication complex	30	1.12e-01	-0.167000	1.86e-01
MASTL Facilitates Mitotic Progression	10	1.13e-01	0.289000	1.87e-01
RA biosynthesis pathway	13	1.13e-01	-0.254000	1.87e-01
Fatty acyl-CoA biosynthesis	35	1.14e-01	0.154000	1.88e-01
Pausing and recovery of Tat-mediated HIV elongation	30	1.14e-01	0.167000	1.88e-01
Tat-mediated HIV elongation arrest and recovery	30	1.14e-01	0.167000	1.88e-01
PI3K/AKT Signaling in Cancer	81	1.15e-01	0.101000	1.89e-01
Switching of origins to a post-replicative state	90	1.17e-01	0.095700	1.92e-01
Class C/3 (Metabotropic glutamate/pheromone receptors)	11	1.17e-01	-0.273000	1.93e-01
BBSome-mediated cargo-targeting to cilium	22	1.18e-01	-0.192000	1.94e-01
Host Interactions of HIV factors	130	1.20e-01	0.078900	1.97e-01
Removal of the Flap Intermediate from the C-strand	17	1.20e-01	-0.218000	1.97e-01
Scavenging by Class A Receptors	12	1.21e-01	0.259000	1.97e-01
Carnitine metabolism	10	1.21e-01	0.283000	1.97e-01
Heme biosynthesis	14	1.21e-01	0.239000	1.98e-01
HIV elongation arrest and recovery	32	1.23e-01	0.158000	2.00e-01
Pausing and recovery of HIV elongation	32	1.23e-01	0.158000	2.00e-01
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	21	1.23e-01	0.194000	2.00e-01
Peroxisomal lipid metabolism	27	1.25e-01	0.171000	2.02e-01
TP53 Regulates Transcription of Cell Death Genes	43	1.25e-01	0.135000	2.02e-01
Regulation of TP53 Activity through Phosphorylation	88	1.26e-01	-0.094500	2.03e-01
Phase I - Functionalization of compounds	65	1.26e-01	0.110000	2.04e-01
Depolymerisation of the Nuclear Lamina	15	1.26e-01	0.228000	2.04e-01
Transport of vitamins, nucleosides, and related molecules	33	1.27e-01	0.153000	2.05e-01
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	14	1.28e-01	0.235000	2.06e-01
Interleukin-15 signaling	14	1.29e-01	0.234000	2.07e-01
Interleukin-6 family signaling	18	1.32e-01	0.205000	2.11e-01
Beta-oxidation of very long chain fatty acids	10	1.32e-01	0.275000	2.11e-01
rRNA processing in the mitochondrion	29	1.33e-01	-0.161000	2.13e-01
Activation of kainate receptors upon glutamate binding	26	1.33e-01	0.170000	2.13e-01
Signaling by FGFR in disease	51	1.34e-01	0.121000	2.13e-01
p75NTR recruits signalling complexes	12	1.36e-01	0.248000	2.18e-01
Viral Messenger RNA Synthesis	44	1.37e-01	-0.130000	2.18e-01
Carboxyterminal post-translational modifications of tubulin	27	1.37e-01	0.165000	2.19e-01
Ca2+ pathway	57	1.39e-01	0.113000	2.22e-01
Phase 0 - rapid depolarisation	28	1.40e-01	-0.161000	2.23e-01
Phase II - Conjugation of compounds	68	1.41e-01	0.103000	2.25e-01
PINK1-PRKN Mediated Mitophagy	21	1.42e-01	0.185000	2.26e-01
ZBP1(DAI) mediated induction of type I IFNs	20	1.43e-01	0.189000	2.26e-01
Downstream signal transduction	27	1.44e-01	0.162000	2.28e-01
Glycolysis	67	1.44e-01	0.103000	2.28e-01
tRNA processing in the mitochondrion	32	1.45e-01	-0.149000	2.29e-01
Amine ligand-binding receptors	10	1.49e-01	-0.264000	2.35e-01
Signaling by ERBB2 KD Mutants	20	1.50e-01	0.186000	2.36e-01
Negative epigenetic regulation of rRNA expression	65	1.50e-01	0.103000	2.37e-01
NRIF signals cell death from the nucleus	15	1.52e-01	0.213000	2.40e-01
Synthesis of very long-chain fatty acyl-CoAs	22	1.53e-01	0.176000	2.41e-01
Metabolism of cofactors	19	1.53e-01	0.189000	2.41e-01
CD209 (DC-SIGN) signaling	20	1.54e-01	0.184000	2.41e-01
Bile acid and bile salt metabolism	28	1.58e-01	0.154000	2.47e-01
Purine ribonucleoside monophosphate biosynthesis	10	1.58e-01	-0.258000	2.47e-01
PI3K events in ERBB2 signaling	11	1.59e-01	0.245000	2.47e-01
Constitutive Signaling by Overexpressed ERBB2	11	1.59e-01	0.245000	2.48e-01
GRB2 events in ERBB2 signaling	11	1.60e-01	0.245000	2.49e-01
RIP-mediated NFkB activation via ZBP1	17	1.63e-01	0.196000	2.53e-01
Constitutive Signaling by AKT1 E17K in Cancer	26	1.63e-01	0.158000	2.53e-01
Classical antibody-mediated complement activation	69	1.63e-01	-0.097100	2.53e-01
Metabolic disorders of biological oxidation enzymes	26	1.67e-01	0.157000	2.58e-01
RUNX3 regulates NOTCH signaling	14	1.67e-01	0.213000	2.58e-01
RNA Polymerase III Chain Elongation	18	1.67e-01	-0.188000	2.58e-01
IRAK2 mediated activation of TAK1 complex	10	1.68e-01	0.252000	2.60e-01
Signaling by ERBB2 TMD/JMD mutants	17	1.69e-01	0.193000	2.61e-01
TCR signaling	122	1.69e-01	0.072100	2.61e-01
Formation of TC-NER Pre-Incision Complex	53	1.70e-01	0.109000	2.62e-01
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	73	1.72e-01	0.092500	2.64e-01
G alpha (s) signalling events	143	1.73e-01	0.066000	2.66e-01
NCAM1 interactions	23	1.73e-01	-0.164000	2.66e-01
Signaling by FGFR2	60	1.77e-01	0.101000	2.71e-01
Acyl chain remodelling of PG	11	1.82e-01	0.232000	2.79e-01
CD22 mediated BCR regulation	59	1.83e-01	-0.100000	2.79e-01
PKA-mediated phosphorylation of CREB	17	1.83e-01	0.186000	2.80e-01
Activation of NMDA receptors and postsynaptic events	58	1.85e-01	0.101000	2.82e-01
Biosynthesis of DHA-derived SPMs	14	1.87e-01	0.203000	2.85e-01
Signaling by FGFR	69	1.87e-01	0.091800	2.85e-01
Tryptophan catabolism	12	1.88e-01	0.220000	2.86e-01
Meiotic recombination	38	1.90e-01	0.123000	2.88e-01
RNA Polymerase I Transcription Termination	30	1.90e-01	-0.138000	2.89e-01
Recruitment of NuMA to mitotic centrosomes	80	1.95e-01	-0.083800	2.95e-01
HS-GAG biosynthesis	20	1.97e-01	0.167000	2.97e-01
Abortive elongation of HIV-1 transcript in the absence of Tat	23	1.98e-01	0.155000	2.99e-01
Transcriptional Regulation by TP53	352	2.00e-01	0.039800	3.02e-01
Anchoring of the basal body to the plasma membrane	97	2.02e-01	-0.075000	3.04e-01
Plasma lipoprotein assembly	10	2.02e-01	0.233000	3.05e-01
Purine salvage	12	2.04e-01	0.212000	3.08e-01
Role of phospholipids in phagocytosis	88	2.06e-01	-0.077900	3.10e-01
Glutamate binding, activation of AMPA receptors and synaptic plasticity	20	2.07e-01	0.163000	3.11e-01
Trafficking of AMPA receptors	20	2.07e-01	0.163000	3.11e-01
Initial triggering of complement	78	2.09e-01	-0.082200	3.14e-01
Regulation of MECP2 expression and activity	28	2.10e-01	0.137000	3.14e-01
Deadenylation of mRNA	22	2.11e-01	0.154000	3.16e-01
Translation of structural proteins	28	2.12e-01	0.136000	3.16e-01
Creation of C4 and C2 activators	71	2.12e-01	-0.085700	3.16e-01
Signaling by PDGFR in disease	19	2.14e-01	0.165000	3.20e-01
Centrosome maturation	81	2.15e-01	-0.079700	3.20e-01
Recruitment of mitotic centrosome proteins and complexes	81	2.15e-01	-0.079700	3.20e-01
Non-integrin membrane-ECM interactions	37	2.16e-01	0.118000	3.20e-01
Regulation of HSF1-mediated heat shock response	79	2.16e-01	-0.080600	3.20e-01
VEGFR2 mediated cell proliferation	18	2.16e-01	0.168000	3.20e-01
Negative regulation of NMDA receptor-mediated neuronal transmission	14	2.18e-01	-0.190000	3.22e-01
Formation of the Early Elongation Complex	33	2.18e-01	0.124000	3.22e-01
Formation of the HIV-1 Early Elongation Complex	33	2.18e-01	0.124000	3.22e-01
Transcriptional activation of mitochondrial biogenesis	51	2.18e-01	0.099700	3.22e-01
RNA Pol II CTD phosphorylation and interaction with CE	27	2.20e-01	0.136000	3.24e-01
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	27	2.20e-01	0.136000	3.24e-01
Adenylate cyclase inhibitory pathway	11	2.21e-01	0.213000	3.25e-01
Downstream TCR signaling	101	2.21e-01	0.070500	3.25e-01
Dectin-2 family	19	2.23e-01	0.162000	3.27e-01
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	18	2.23e-01	0.166000	3.27e-01
Cobalamin (Cbl, vitamin B12) transport and metabolism	17	2.24e-01	-0.170000	3.28e-01
DAG and IP3 signaling	33	2.26e-01	0.122000	3.31e-01
ECM proteoglycans	35	2.26e-01	0.118000	3.31e-01
Synthesis of bile acids and bile salts	24	2.27e-01	0.142000	3.32e-01
Cyclin A/B1/B2 associated events during G2/M transition	25	2.28e-01	0.139000	3.33e-01
Late Phase of HIV Life Cycle	131	2.29e-01	0.060900	3.34e-01
Cytosolic iron-sulfur cluster assembly	13	2.30e-01	-0.192000	3.34e-01
Peptide ligand-binding receptors	97	2.32e-01	0.070200	3.38e-01
Unblocking of NMDA receptors, glutamate binding and activation	12	2.33e-01	-0.199000	3.39e-01
Nuclear Envelope Breakdown	53	2.34e-01	-0.094500	3.40e-01
Mitotic Prometaphase	185	2.37e-01	-0.050400	3.43e-01
Adrenaline,noradrenaline inhibits insulin secretion	24	2.37e-01	0.139000	3.43e-01
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	38	2.37e-01	-0.111000	3.43e-01
Heparan sulfate/heparin (HS-GAG) metabolism	37	2.38e-01	0.112000	3.44e-01
Chromatin modifying enzymes	218	2.40e-01	0.046200	3.45e-01
Chromatin organization	218	2.40e-01	0.046200	3.45e-01
SUMOylation	166	2.40e-01	-0.052900	3.45e-01
Synthesis of PIPs at the late endosome membrane	11	2.41e-01	0.204000	3.47e-01
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	104	2.43e-01	-0.066200	3.49e-01
RNA Polymerase III Transcription Initiation From Type 3 Promoter	28	2.44e-01	-0.127000	3.50e-01
Transcription of the HIV genome	67	2.44e-01	0.082300	3.50e-01
Formation of HIV-1 elongation complex containing HIV-1 Tat	42	2.45e-01	0.104000	3.51e-01
HIV Transcription Elongation	42	2.45e-01	0.104000	3.51e-01
Tat-mediated elongation of the HIV-1 transcript	42	2.45e-01	0.104000	3.51e-01
Other semaphorin interactions	16	2.46e-01	0.167000	3.52e-01
Signaling by NTRK2 (TRKB)	20	2.47e-01	0.150000	3.53e-01
Cellular response to heat stress	93	2.49e-01	-0.069200	3.54e-01
Formation of HIV elongation complex in the absence of HIV Tat	44	2.51e-01	0.100000	3.57e-01
HSF1-dependent transactivation	29	2.52e-01	0.123000	3.58e-01
Assembly of active LPL and LIPC lipase complexes	10	2.54e-01	0.208000	3.61e-01
Post NMDA receptor activation events	48	2.56e-01	0.094800	3.63e-01
Miscellaneous transport and binding events	20	2.56e-01	0.147000	3.63e-01
A tetrasaccharide linker sequence is required for GAG synthesis	17	2.57e-01	-0.159000	3.64e-01
Signaling by NOTCH2	30	2.61e-01	0.119000	3.69e-01
RAF-independent MAPK1/3 activation	21	2.64e-01	0.141000	3.73e-01
Cytosolic tRNA aminoacylation	24	2.65e-01	-0.132000	3.74e-01
DNA Damage Bypass	47	2.65e-01	-0.093900	3.74e-01
Synthesis of PE	12	2.69e-01	-0.184000	3.79e-01
Cytosolic sulfonation of small molecules	19	2.72e-01	0.146000	3.83e-01
Disorders of developmental biology	12	2.75e-01	0.182000	3.86e-01
Loss of function of MECP2 in Rett syndrome	12	2.75e-01	0.182000	3.86e-01
Pervasive developmental disorders	12	2.75e-01	0.182000	3.86e-01
Regulation of IFNA signaling	12	2.76e-01	0.182000	3.87e-01
ADORA2B mediated anti-inflammatory cytokines production	73	2.77e-01	0.073600	3.88e-01
Regulation of localization of FOXO transcription factors	12	2.77e-01	0.181000	3.88e-01
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	46	2.77e-01	0.092600	3.88e-01
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	12	2.78e-01	0.181000	3.88e-01
Blood group systems biosynthesis	17	2.79e-01	0.152000	3.89e-01
NRAGE signals death through JNK	53	2.79e-01	0.085900	3.89e-01
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	25	2.80e-01	0.125000	3.89e-01
Amino acid transport across the plasma membrane	24	2.83e-01	0.127000	3.94e-01
Metal ion SLC transporters	21	2.85e-01	0.135000	3.95e-01
G2/M Checkpoints	140	2.87e-01	0.052100	3.98e-01
Regulation of TNFR1 signaling	32	2.87e-01	-0.109000	3.98e-01
Telomere Extension By Telomerase	23	2.88e-01	-0.128000	3.98e-01
Olfactory Signaling Pathway	60	2.89e-01	0.079100	4.00e-01
Cohesin Loading onto Chromatin	10	2.92e-01	0.192000	4.04e-01
Diseases of metabolism	191	2.93e-01	0.044100	4.04e-01
Aflatoxin activation and detoxification	14	2.94e-01	0.162000	4.06e-01
Keratan sulfate/keratin metabolism	27	2.95e-01	0.116000	4.07e-01
FRS-mediated FGFR3 signaling	11	2.96e-01	0.182000	4.07e-01
Metabolism of amine-derived hormones	10	2.97e-01	-0.190000	4.08e-01
Signaling by ERBB2 ECD mutants	15	3.00e-01	0.155000	4.12e-01
Vitamin B5 (pantothenate) metabolism	17	3.01e-01	0.145000	4.13e-01
Formation of the ternary complex, and subsequently, the 43S complex	51	3.03e-01	-0.083400	4.14e-01
RNA Polymerase III Abortive And Retractive Initiation	41	3.03e-01	-0.093000	4.14e-01
RNA Polymerase III Transcription	41	3.03e-01	-0.093000	4.14e-01
Transcriptional regulation by small RNAs	63	3.05e-01	0.074700	4.17e-01
Positive epigenetic regulation of rRNA expression	62	3.06e-01	0.075200	4.17e-01
CD28 dependent Vav1 pathway	12	3.06e-01	0.171000	4.18e-01
Signaling by FGFR2 IIIa TM	18	3.08e-01	0.139000	4.20e-01
Cytochrome P450 - arranged by substrate type	36	3.14e-01	0.097000	4.27e-01
Inositol phosphate metabolism	42	3.17e-01	0.089200	4.31e-01
VEGFR2 mediated vascular permeability	27	3.24e-01	0.110000	4.40e-01
Regulation of beta-cell development	19	3.25e-01	0.131000	4.40e-01
Early Phase of HIV Life Cycle	14	3.25e-01	-0.152000	4.40e-01
MET activates PTK2 signaling	15	3.26e-01	0.146000	4.42e-01
SUMO E3 ligases SUMOylate target proteins	160	3.29e-01	-0.044700	4.46e-01
Regulation of expression of SLITs and ROBOs	161	3.30e-01	-0.044500	4.46e-01
Transcriptional regulation of pluripotent stem cells	20	3.32e-01	0.125000	4.48e-01
Defects in cobalamin (B12) metabolism	13	3.32e-01	-0.155000	4.48e-01
E2F mediated regulation of DNA replication	22	3.32e-01	-0.119000	4.48e-01
Nonhomologous End-Joining (NHEJ)	42	3.34e-01	0.086200	4.49e-01
The phototransduction cascade	26	3.34e-01	-0.109000	4.49e-01
Metabolism of folate and pterines	16	3.34e-01	0.139000	4.49e-01
Interleukin-2 family signaling	38	3.35e-01	0.090500	4.49e-01
Platelet calcium homeostasis	22	3.35e-01	0.119000	4.50e-01
HS-GAG degradation	16	3.36e-01	0.139000	4.51e-01
IGF1R signaling cascade	36	3.37e-01	0.092400	4.51e-01
Class I peroxisomal membrane protein import	20	3.39e-01	-0.124000	4.53e-01
Processing of Capped Intron-Containing Pre-mRNA	238	3.40e-01	-0.035900	4.55e-01
Translesion Synthesis by POLH	18	3.41e-01	-0.130000	4.55e-01
RAS processing	19	3.42e-01	0.126000	4.56e-01
Maturation of nucleoprotein	10	3.42e-01	-0.173000	4.56e-01
DNA Double Strand Break Response	47	3.43e-01	0.080000	4.56e-01
Polo-like kinase mediated events	16	3.44e-01	0.137000	4.58e-01
mitochondrial fatty acid beta-oxidation of saturated fatty acids	11	3.46e-01	0.164000	4.59e-01
Molecules associated with elastic fibres	22	3.46e-01	0.116000	4.59e-01
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	17	3.51e-01	-0.131000	4.66e-01
FRS-mediated FGFR4 signaling	12	3.52e-01	0.155000	4.66e-01
NOTCH2 intracellular domain regulates transcription	11	3.54e-01	0.161000	4.68e-01
Nef mediated downregulation of MHC class I complex cell surface expression	10	3.54e-01	0.169000	4.68e-01
NOTCH2 Activation and Transmission of Signal to the Nucleus	20	3.55e-01	0.119000	4.69e-01
Degradation of cysteine and homocysteine	12	3.56e-01	0.154000	4.70e-01
Downregulation of ERBB2:ERBB3 signaling	12	3.56e-01	0.154000	4.70e-01
PKMTs methylate histone lysines	45	3.57e-01	-0.079400	4.70e-01
Incretin synthesis, secretion, and inactivation	10	3.58e-01	0.168000	4.70e-01
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	10	3.58e-01	0.168000	4.70e-01
Downstream signaling of activated FGFR3	16	3.59e-01	0.132000	4.71e-01
HIV Life Cycle	144	3.61e-01	0.044100	4.74e-01
Activation of RAC1	11	3.65e-01	0.158000	4.78e-01
Regulation of TP53 Activity through Methylation	19	3.68e-01	-0.119000	4.82e-01
NCAM signaling for neurite out-growth	43	3.69e-01	-0.079200	4.82e-01
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	36	3.71e-01	0.086100	4.85e-01
DDX58/IFIH1-mediated induction of interferon-alpha/beta	63	3.72e-01	0.065000	4.86e-01
SUMOylation of transcription factors	16	3.74e-01	0.128000	4.88e-01
FRS-mediated FGFR1 signaling	14	3.75e-01	0.137000	4.88e-01
Acyl chain remodelling of PS	14	3.80e-01	0.136000	4.94e-01
Ephrin signaling	18	3.81e-01	0.119000	4.95e-01
Zinc transporters	14	3.85e-01	0.134000	5.01e-01
Interconversion of nucleotide di- and triphosphates	27	3.89e-01	0.095700	5.05e-01
Protein methylation	15	3.91e-01	0.128000	5.07e-01
Regulation of TP53 Activity through Association with Co-factors	12	3.93e-01	-0.143000	5.08e-01
Diseases associated with glycosaminoglycan metabolism	26	3.94e-01	0.096500	5.10e-01
Long-term potentiation	14	3.95e-01	-0.131000	5.10e-01
Post-translational modification: synthesis of GPI-anchored proteins	57	3.95e-01	0.065100	5.10e-01
Downstream signaling of activated FGFR4	17	4.05e-01	0.117000	5.23e-01
Loss of Nlp from mitotic centrosomes	69	4.07e-01	-0.057700	5.24e-01
Loss of proteins required for interphase microtubule organization from the centrosome	69	4.07e-01	-0.057700	5.24e-01
RUNX2 regulates osteoblast differentiation	19	4.08e-01	-0.110000	5.24e-01
Chondroitin sulfate/dermatan sulfate metabolism	38	4.08e-01	0.077600	5.24e-01
S Phase	161	4.08e-01	-0.037800	5.24e-01
IRS-related events triggered by IGF1R	35	4.10e-01	0.080600	5.25e-01
Ras activation upon Ca2+ influx through NMDA receptor	15	4.10e-01	-0.123000	5.26e-01
Base Excision Repair	58	4.13e-01	-0.062200	5.28e-01
SLBP independent Processing of Histone Pre-mRNAs	10	4.15e-01	-0.149000	5.31e-01
Transport of inorganic cations/anions and amino acids/oligopeptides	80	4.15e-01	0.052700	5.31e-01
HSF1 activation	26	4.17e-01	0.092000	5.32e-01
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	13	4.17e-01	0.130000	5.32e-01
mRNA Capping	29	4.18e-01	0.086900	5.33e-01
Assembly and cell surface presentation of NMDA receptors	18	4.18e-01	-0.110000	5.33e-01
Interleukin receptor SHC signaling	23	4.22e-01	0.096700	5.37e-01
Mitochondrial calcium ion transport	22	4.22e-01	0.098800	5.37e-01
Repression of WNT target genes	14	4.23e-01	-0.124000	5.37e-01
FCERI mediated Ca+2 mobilization	89	4.25e-01	-0.049000	5.39e-01
Adherens junctions interactions	19	4.25e-01	0.106000	5.39e-01
Signaling by WNT in cancer	30	4.25e-01	0.084100	5.39e-01
FCGR3A-mediated IL10 synthesis	99	4.29e-01	-0.046000	5.43e-01
Cell-cell junction organization	39	4.30e-01	0.073000	5.44e-01
Cyclin D associated events in G1	47	4.32e-01	0.066300	5.45e-01
G1 Phase	47	4.32e-01	0.066300	5.45e-01
Cholesterol biosynthesis	24	4.36e-01	0.091900	5.49e-01
G1/S-Specific Transcription	29	4.36e-01	-0.083600	5.49e-01
Synthesis of IP3 and IP4 in the cytosol	22	4.41e-01	0.095000	5.54e-01
Neurotransmitter release cycle	39	4.42e-01	0.071100	5.56e-01
Interleukin-20 family signaling	17	4.42e-01	0.108000	5.56e-01
Activation of BH3-only proteins	30	4.43e-01	0.081000	5.56e-01
Binding and Uptake of Ligands by Scavenger Receptors	93	4.44e-01	0.046000	5.56e-01
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	37	4.46e-01	0.072300	5.59e-01
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	10	4.54e-01	0.137000	5.68e-01
Constitutive Signaling by Aberrant PI3K in Cancer	54	4.55e-01	0.058800	5.68e-01
SUMOylation of transcription cofactors	44	4.58e-01	0.064700	5.72e-01
RNA Polymerase I Promoter Clearance	66	4.60e-01	0.052600	5.73e-01
RNA Polymerase I Transcription	66	4.60e-01	0.052600	5.73e-01
Signaling by Activin	10	4.60e-01	-0.135000	5.73e-01
Ovarian tumor domain proteases	37	4.64e-01	0.069600	5.77e-01
Phase 4 - resting membrane potential	10	4.66e-01	0.133000	5.79e-01
Regulation of pyruvate dehydrogenase (PDH) complex	15	4.67e-01	0.108000	5.80e-01
Global Genome Nucleotide Excision Repair (GG-NER)	84	4.67e-01	-0.045900	5.80e-01
Synthesis of DNA	119	4.71e-01	-0.038300	5.84e-01
Folding of actin by CCT/TriC	10	4.72e-01	0.131000	5.84e-01
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	43	4.74e-01	0.063100	5.87e-01
Downstream signaling of activated FGFR1	20	4.79e-01	0.091500	5.92e-01
Telomere Maintenance	80	4.82e-01	-0.045500	5.96e-01
Reproduction	80	4.86e-01	0.045100	5.99e-01
TP53 Regulates Transcription of Cell Cycle Genes	48	4.89e-01	0.057800	6.02e-01
Downregulation of SMAD2/3:SMAD4 transcriptional activity	23	4.89e-01	0.083400	6.02e-01
Cell Cycle, Mitotic	503	4.89e-01	0.018000	6.02e-01
RUNX3 regulates p14-ARF	10	4.90e-01	0.126000	6.03e-01
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	23	4.92e-01	0.082800	6.04e-01
TNFs bind their physiological receptors	25	4.94e-01	-0.079100	6.06e-01
APC/C:Cdc20 mediated degradation of Cyclin B	24	4.95e-01	0.080500	6.07e-01
Cellular hexose transport	15	4.96e-01	-0.101000	6.08e-01
Metabolism of vitamins and cofactors	156	4.99e-01	0.031400	6.11e-01
Inactivation, recovery and regulation of the phototransduction cascade	25	5.00e-01	-0.077900	6.12e-01
FCERI mediated MAPK activation	90	5.03e-01	0.040900	6.14e-01
MECP2 regulates neuronal receptors and channels	13	5.04e-01	0.107000	6.15e-01
Nicotinamide salvaging	14	5.04e-01	-0.103000	6.15e-01
Processing of Intronless Pre-mRNAs	19	5.08e-01	-0.087800	6.19e-01
O-linked glycosylation	84	5.09e-01	-0.041700	6.19e-01
TP53 Regulates Transcription of DNA Repair Genes	61	5.09e-01	-0.048900	6.19e-01
DNA Replication Pre-Initiation	83	5.15e-01	0.041300	6.26e-01
Phase 2 - plateau phase	17	5.17e-01	-0.090800	6.28e-01
Metabolism of water-soluble vitamins and cofactors	110	5.17e-01	-0.035700	6.28e-01
Mitotic G1 phase and G1/S transition	148	5.19e-01	0.030700	6.29e-01
Regulation of KIT signaling	15	5.21e-01	0.095700	6.31e-01
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	91	5.23e-01	-0.038700	6.32e-01
Amplification of signal from the kinetochores	91	5.23e-01	-0.038700	6.32e-01
IRS-mediated signalling	34	5.25e-01	0.063000	6.34e-01
Regulation of FOXO transcriptional activity by acetylation	10	5.27e-01	0.116000	6.36e-01
SHC-mediated cascade:FGFR4	10	5.33e-01	0.114000	6.43e-01
Nephrin family interactions	18	5.34e-01	-0.084600	6.44e-01
Purine catabolism	16	5.37e-01	0.089200	6.46e-01
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	17	5.42e-01	-0.085300	6.52e-01
Transcriptional Regulation by VENTX	38	5.42e-01	-0.057100	6.52e-01
Caspase-mediated cleavage of cytoskeletal proteins	12	5.49e-01	0.099800	6.60e-01
Cargo trafficking to the periciliary membrane	47	5.50e-01	0.050400	6.60e-01
SHC-mediated cascade:FGFR1	12	5.51e-01	0.099400	6.60e-01
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	84	5.52e-01	-0.037600	6.61e-01
N-Glycan antennae elongation	13	5.53e-01	-0.095000	6.62e-01
STING mediated induction of host immune responses	15	5.55e-01	0.088100	6.63e-01
Acetylcholine Neurotransmitter Release Cycle	11	5.56e-01	-0.103000	6.64e-01
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	17	5.57e-01	-0.082300	6.64e-01
Mitotic Spindle Checkpoint	108	5.59e-01	-0.032600	6.66e-01
Interleukin-7 signaling	21	5.60e-01	0.073400	6.68e-01
Endosomal/Vacuolar pathway	12	5.64e-01	-0.096100	6.72e-01
Basigin interactions	23	5.66e-01	0.069100	6.73e-01
mRNA Splicing - Minor Pathway	52	5.69e-01	0.045700	6.75e-01
Glutamate and glutamine metabolism	12	5.73e-01	-0.094000	6.80e-01
Synthesis of glycosylphosphatidylinositol (GPI)	17	5.75e-01	-0.078600	6.81e-01
MicroRNA (miRNA) biogenesis	24	5.75e-01	0.066100	6.81e-01
Synthesis of IP2, IP, and Ins in the cytosol	13	5.75e-01	0.089700	6.81e-01
AURKA Activation by TPX2	72	5.76e-01	-0.038100	6.82e-01
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	19	5.79e-01	-0.073500	6.85e-01
Class A/1 (Rhodopsin-like receptors)	169	5.81e-01	0.024600	6.86e-01
Sema3A PAK dependent Axon repulsion	16	5.86e-01	0.078600	6.91e-01
PERK regulates gene expression	31	5.87e-01	0.056400	6.91e-01
Meiosis	68	5.88e-01	0.038000	6.92e-01
PI-3K cascade:FGFR4	10	5.89e-01	0.098800	6.92e-01
TRP channels	19	5.89e-01	-0.071600	6.92e-01
The canonical retinoid cycle in rods (twilight vision)	10	5.90e-01	0.098500	6.92e-01
Condensation of Prometaphase Chromosomes	11	5.90e-01	0.093900	6.92e-01
WNT ligand biogenesis and trafficking	21	5.93e-01	0.067300	6.96e-01
Elevation of cytosolic Ca2+ levels	13	5.94e-01	0.085500	6.96e-01
FGFR2 alternative splicing	25	5.99e-01	0.060800	7.01e-01
CD28 co-stimulation	33	5.99e-01	-0.052800	7.01e-01
PI-3K cascade:FGFR1	12	6.02e-01	0.086900	7.04e-01
PI3K Cascade	30	6.07e-01	0.054200	7.09e-01
Fertilization	12	6.10e-01	0.085100	7.12e-01
Regulation of RUNX1 Expression and Activity	18	6.11e-01	-0.069200	7.13e-01
Scavenging of heme from plasma	71	6.17e-01	-0.034400	7.18e-01
mRNA 3'-end processing	56	6.17e-01	-0.038700	7.18e-01
Signaling by NTRK3 (TRKC)	16	6.18e-01	0.072000	7.18e-01
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	27	6.21e-01	0.054900	7.22e-01
DNA Replication	126	6.24e-01	-0.025300	7.24e-01
Association of TriC/CCT with target proteins during biosynthesis	37	6.28e-01	0.046000	7.28e-01
Lysine catabolism	11	6.30e-01	0.083900	7.30e-01
Gamma carboxylation, hypusine formation and arylsulfatase activation	34	6.31e-01	0.047600	7.30e-01
RIPK1-mediated regulated necrosis	16	6.33e-01	0.069000	7.31e-01
Regulated Necrosis	16	6.33e-01	0.069000	7.31e-01
NOTCH4 Intracellular Domain Regulates Transcription	18	6.34e-01	0.064800	7.32e-01
Cytosolic sensors of pathogen-associated DNA	62	6.36e-01	0.034700	7.34e-01
Branched-chain amino acid catabolism	21	6.37e-01	-0.059600	7.34e-01
Mitochondrial protein import	64	6.41e-01	0.033700	7.38e-01
Prolactin receptor signaling	11	6.41e-01	0.081100	7.38e-01
Deactivation of the beta-catenin transactivating complex	36	6.47e-01	0.044100	7.44e-01
Processing of DNA double-strand break ends	71	6.48e-01	-0.031300	7.45e-01
Competing endogenous RNAs (ceRNAs) regulate PTEN translation	11	6.49e-01	-0.079300	7.45e-01
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	11	6.50e-01	-0.079100	7.45e-01
Processing of Capped Intronless Pre-mRNA	28	6.53e-01	-0.049100	7.48e-01
Interleukin-37 signaling	19	6.53e-01	0.059600	7.48e-01
Voltage gated Potassium channels	25	6.54e-01	0.051800	7.48e-01
Netrin-1 signaling	40	6.56e-01	0.040700	7.50e-01
Ion transport by P-type ATPases	43	6.57e-01	0.039100	7.50e-01
Cell Cycle	625	6.60e-01	-0.010300	7.53e-01
G2/M DNA damage checkpoint	68	6.63e-01	-0.030500	7.56e-01
TICAM1-dependent activation of IRF3/IRF7	12	6.65e-01	0.072300	7.57e-01
Formation of Incision Complex in GG-NER	43	6.70e-01	0.037500	7.63e-01
Other interleukin signaling	18	6.71e-01	0.057800	7.64e-01
TP53 Regulates Transcription of Death Receptors and Ligands	12	6.74e-01	0.070200	7.66e-01
Gap-filling DNA repair synthesis and ligation in TC-NER	64	6.75e-01	-0.030300	7.67e-01
TRAF6 mediated IRF7 activation	15	6.77e-01	0.062100	7.69e-01
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)	10	6.80e-01	-0.075200	7.72e-01
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	25	6.82e-01	0.047400	7.72e-01
Signaling by FGFR4 in disease	11	6.85e-01	0.070700	7.75e-01
Signaling by FGFR2 in disease	32	6.86e-01	0.041200	7.76e-01
RNA Polymerase II Transcription Termination	65	6.88e-01	-0.028800	7.77e-01
Organelle biogenesis and maintenance	269	6.88e-01	-0.014200	7.77e-01
Cell Cycle Checkpoints	260	6.92e-01	0.014300	7.81e-01
TP53 Regulates Transcription of Caspase Activators and Caspases	12	6.95e-01	-0.065400	7.83e-01
Synthesis, secretion, and deacylation of Ghrelin	11	6.96e-01	-0.068000	7.84e-01
DAP12 signaling	28	7.02e-01	0.041800	7.90e-01
Regulation of PTEN mRNA translation	13	7.06e-01	-0.060400	7.94e-01
Anti-inflammatory response favouring Leishmania parasite infection	169	7.09e-01	0.016600	7.96e-01
Leishmania parasite growth and survival	169	7.09e-01	0.016600	7.96e-01
Receptor-type tyrosine-protein phosphatases	12	7.09e-01	0.062100	7.96e-01
Synthesis of PA	32	7.10e-01	0.038000	7.96e-01
PI-3K cascade:FGFR2	12	7.14e-01	-0.061100	8.00e-01
Diseases associated with N-glycosylation of proteins	17	7.17e-01	0.050700	8.03e-01
Establishment of Sister Chromatid Cohesion	11	7.19e-01	0.062700	8.04e-01
RHO GTPases Activate Formins	117	7.21e-01	0.019100	8.05e-01
Eicosanoid ligand-binding receptors	13	7.22e-01	-0.056900	8.06e-01
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	20	7.25e-01	-0.045500	8.08e-01
Synthesis of PIPs at the Golgi membrane	16	7.25e-01	0.050800	8.08e-01
Xenobiotics	12	7.26e-01	-0.058500	8.08e-01
Pregnenolone biosynthesis	10	7.29e-01	0.063400	8.11e-01
Signaling by KIT in disease	20	7.31e-01	-0.044400	8.12e-01
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	20	7.31e-01	-0.044400	8.12e-01
Aberrant regulation of mitotic cell cycle due to RB1 defects	36	7.35e-01	-0.032700	8.14e-01
Diseases of mitotic cell cycle	36	7.35e-01	-0.032700	8.14e-01
RNA Polymerase III Transcription Termination	23	7.35e-01	-0.040800	8.14e-01
EML4 and NUDC in mitotic spindle formation	95	7.36e-01	-0.020000	8.15e-01
GPCR ligand binding	235	7.37e-01	0.012700	8.15e-01
Ribosomal scanning and start codon recognition	58	7.39e-01	-0.025300	8.17e-01
Phosphorylation of the APC/C	20	7.43e-01	0.042300	8.21e-01
Visual phototransduction	60	7.45e-01	0.024300	8.22e-01
Regulation of PLK1 Activity at G2/M Transition	87	7.48e-01	-0.019900	8.25e-01
Glutamate Neurotransmitter Release Cycle	20	7.51e-01	-0.041100	8.27e-01
Signaling by ROBO receptors	201	7.52e-01	-0.012900	8.28e-01
Processing of SMDT1	15	7.57e-01	0.046100	8.33e-01
TNFR1-induced NFkappaB signaling pathway	25	7.59e-01	-0.035400	8.35e-01
Processing and activation of SUMO	10	7.60e-01	0.055700	8.35e-01
Glucagon-type ligand receptors	20	7.61e-01	0.039300	8.35e-01
Sulfur amino acid metabolism	22	7.63e-01	0.037100	8.37e-01
Role of LAT2/NTAL/LAB on calcium mobilization	74	7.69e-01	-0.019800	8.42e-01
HATs acetylate histones	93	7.69e-01	-0.017600	8.42e-01
SHC-mediated cascade:FGFR2	12	7.71e-01	-0.048500	8.43e-01
Signaling by NODAL	13	7.71e-01	-0.046600	8.43e-01
Termination of O-glycan biosynthesis	16	7.74e-01	0.041500	8.45e-01
Neurexins and neuroligins	37	7.74e-01	-0.027300	8.45e-01
TRAF3-dependent IRF activation pathway	13	7.76e-01	0.045500	8.46e-01
Epigenetic regulation of gene expression	103	7.84e-01	0.015700	8.54e-01
Dual incision in TC-NER	65	7.87e-01	-0.019400	8.57e-01
Translation initiation complex formation	58	7.90e-01	-0.020200	8.59e-01
Mitochondrial Fatty Acid Beta-Oxidation	36	7.92e-01	0.025400	8.60e-01
Class B/2 (Secretin family receptors)	56	7.94e-01	0.020200	8.62e-01
Norepinephrine Neurotransmitter Release Cycle	14	7.94e-01	0.040300	8.62e-01
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	11	8.02e-01	0.043800	8.69e-01
Defective B4GALT7 causes EDS, progeroid type	11	8.03e-01	-0.043500	8.70e-01
Lewis blood group biosynthesis	13	8.04e-01	0.039800	8.70e-01
Cardiac conduction	92	8.06e-01	0.014800	8.72e-01
SUMOylation of DNA methylation proteins	16	8.08e-01	-0.035200	8.72e-01
Deposition of new CENPA-containing nucleosomes at the centromere	40	8.08e-01	0.022200	8.72e-01
Nucleosome assembly	40	8.08e-01	0.022200	8.72e-01
Collagen chain trimerization	27	8.10e-01	0.026700	8.73e-01
Inactivation of APC/C via direct inhibition of the APC/C complex	21	8.14e-01	-0.029600	8.76e-01
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	21	8.14e-01	-0.029600	8.76e-01
Mitochondrial translation termination	91	8.18e-01	-0.014000	8.79e-01
IL-6-type cytokine receptor ligand interactions	12	8.18e-01	0.038400	8.79e-01
Vitamin D (calciferol) metabolism	10	8.20e-01	0.041600	8.81e-01
HCMV Early Events	74	8.23e-01	0.015000	8.83e-01
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	14	8.24e-01	-0.034400	8.83e-01
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	12	8.26e-01	0.036700	8.84e-01
Interleukin-2 signaling	11	8.26e-01	0.038300	8.84e-01
CDC6 association with the ORC:origin complex	11	8.28e-01	-0.037900	8.85e-01
Mitochondrial translation elongation	91	8.28e-01	-0.013200	8.85e-01
IRF3-mediated induction of type I IFN	12	8.35e-01	-0.034700	8.92e-01
RUNX2 regulates bone development	24	8.39e-01	-0.024000	8.95e-01
Interaction between L1 and Ankyrins	22	8.40e-01	0.024900	8.95e-01
Serotonin Neurotransmitter Release Cycle	15	8.43e-01	0.029600	8.95e-01
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects	17	8.43e-01	-0.027800	8.95e-01
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	17	8.43e-01	-0.027800	8.95e-01
N-glycan antennae elongation in the medial/trans-Golgi	21	8.43e-01	-0.025000	8.95e-01
Metabolism of amino acids and derivatives	326	8.44e-01	-0.006360	8.95e-01
Activation of SMO	13	8.44e-01	0.031500	8.95e-01
CLEC7A (Dectin-1) induces NFAT activation	11	8.44e-01	-0.034200	8.95e-01
Signaling by Retinoic Acid	31	8.45e-01	0.020200	8.95e-01
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	16	8.46e-01	-0.028100	8.95e-01
Protein-protein interactions at synapses	58	8.47e-01	0.014700	8.96e-01
GABA synthesis, release, reuptake and degradation	13	8.49e-01	-0.030400	8.97e-01
Nucleotide-like (purinergic) receptors	13	8.49e-01	0.030400	8.97e-01
APC-Cdc20 mediated degradation of Nek2A	26	8.54e-01	0.020800	9.02e-01
KSRP (KHSRP) binds and destabilizes mRNA	17	8.60e-01	-0.024700	9.07e-01
Nucleotide Excision Repair	110	8.60e-01	-0.009710	9.07e-01
Regulation of TP53 Expression and Degradation	36	8.61e-01	-0.016800	9.07e-01
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	14	8.63e-01	-0.026700	9.08e-01
G0 and Early G1	27	8.65e-01	0.018900	9.10e-01
PIWI-interacting RNA (piRNA) biogenesis	24	8.66e-01	0.019900	9.10e-01
Negative regulators of DDX58/IFIH1 signaling	34	8.71e-01	-0.016100	9.14e-01
Constitutive Signaling by NOTCH1 HD Domain Mutants	14	8.81e-01	0.023100	9.24e-01
Signaling by NOTCH1 HD Domain Mutants in Cancer	14	8.81e-01	0.023100	9.24e-01
FGFR2 mutant receptor activation	22	8.82e-01	0.018300	9.24e-01
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	20	8.87e-01	-0.018300	9.28e-01
Deadenylation-dependent mRNA decay	53	8.88e-01	-0.011200	9.28e-01
Methylation	12	8.93e-01	-0.022400	9.33e-01
Mitochondrial translation initiation	91	8.94e-01	-0.008110	9.33e-01
CTLA4 inhibitory signaling	21	8.94e-01	-0.016800	9.33e-01
Transcription-Coupled Nucleotide Excision Repair (TC-NER)	78	9.00e-01	-0.008230	9.38e-01
Resolution of Sister Chromatid Cohesion	104	9.00e-01	-0.007100	9.38e-01
TNF signaling	42	9.01e-01	0.011100	9.38e-01
DNA Damage Recognition in GG-NER	38	9.01e-01	-0.011600	9.38e-01
Interleukin-35 Signalling	12	9.03e-01	-0.020200	9.39e-01
Lysosphingolipid and LPA receptors	11	9.05e-01	-0.020900	9.39e-01
EGR2 and SOX10-mediated initiation of Schwann cell myelination	22	9.05e-01	0.014700	9.39e-01
Keratan sulfate biosynthesis	22	9.05e-01	-0.014700	9.39e-01
Defective B3GALT6 causes EDSP2 and SEMDJL1	11	9.08e-01	-0.020100	9.41e-01
Nicotinate metabolism	25	9.12e-01	-0.012800	9.44e-01
CRMPs in Sema3A signaling	14	9.13e-01	-0.016900	9.44e-01
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	59	9.13e-01	-0.008230	9.44e-01
Regulation of innate immune responses to cytosolic DNA	14	9.14e-01	0.016600	9.45e-01
Diseases of glycosylation	109	9.17e-01	-0.005800	9.46e-01
Downstream signaling of activated FGFR2	19	9.17e-01	0.013700	9.46e-01
mRNA Splicing - Major Pathway	179	9.18e-01	-0.004470	9.46e-01
AKT phosphorylates targets in the nucleus	10	9.23e-01	-0.017600	9.51e-01
FOXO-mediated transcription of cell cycle genes	15	9.24e-01	0.014300	9.51e-01
mRNA decay by 5' to 3' exoribonuclease	15	9.25e-01	-0.014000	9.51e-01
Signaling by FGFR3 in disease	13	9.26e-01	0.014800	9.51e-01
Signaling by FGFR3 point mutants in cancer	13	9.26e-01	0.014800	9.51e-01
Regulation of necroptotic cell death	14	9.26e-01	-0.014300	9.51e-01
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	14	9.27e-01	0.014200	9.51e-01
Kinesins	39	9.28e-01	0.008350	9.51e-01
Transcription of E2F targets under negative control by DREAM complex	19	9.30e-01	0.011600	9.52e-01
Dopamine Neurotransmitter Release Cycle	20	9.31e-01	0.011200	9.52e-01
RMTs methylate histone arginines	37	9.33e-01	0.008010	9.52e-01
Aberrant regulation of mitotic exit in cancer due to RB1 defects	20	9.34e-01	0.010700	9.52e-01
Tight junction interactions	18	9.35e-01	0.011200	9.52e-01
CASP8 activity is inhibited	11	9.35e-01	-0.014300	9.52e-01
Dimerization of procaspase-8	11	9.35e-01	-0.014300	9.52e-01
Regulation by c-FLIP	11	9.35e-01	-0.014300	9.52e-01
Regulation of FZD by ubiquitination	15	9.44e-01	-0.010500	9.60e-01
Signaling by BMP	21	9.44e-01	-0.008810	9.60e-01
Synthesis of PIPs at the early endosome membrane	16	9.46e-01	-0.009840	9.61e-01
FRS-mediated FGFR2 signaling	14	9.47e-01	0.010200	9.62e-01
Glutathione synthesis and recycling	10	9.47e-01	0.012000	9.62e-01
Defective EXT1 causes exostoses 1, TRPS2 and CHDS	10	9.52e-01	0.011100	9.64e-01
Defective EXT2 causes exostoses 2	10	9.52e-01	0.011100	9.64e-01
Gene Silencing by RNA	88	9.54e-01	-0.003580	9.66e-01
G1/S Transition	130	9.54e-01	0.002910	9.66e-01
ATF4 activates genes in response to endoplasmic reticulum stress	26	9.57e-01	-0.006090	9.67e-01
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	31	9.57e-01	0.005560	9.67e-01
Inhibition of replication initiation of damaged DNA by RB1/E2F1	13	9.63e-01	0.007440	9.72e-01
Defective B3GAT3 causes JDSSDHD	11	9.66e-01	-0.007380	9.75e-01
Nuclear Receptor transcription pathway	38	9.71e-01	0.003360	9.79e-01
PECAM1 interactions	12	9.71e-01	-0.005960	9.79e-01
Regulation of Complement cascade	95	9.72e-01	0.002070	9.79e-01
Complement cascade	99	9.76e-01	0.001730	9.82e-01
Synaptic adhesion-like molecules	15	9.77e-01	0.004340	9.82e-01
mRNA Splicing	187	9.78e-01	-0.001160	9.83e-01
Regulation of TP53 Degradation	35	9.81e-01	0.002380	9.84e-01
SLC transporter disorders	77	9.89e-01	0.000929	9.92e-01
Ion homeostasis	41	9.92e-01	-0.000892	9.94e-01
Mitochondrial translation	97	9.93e-01	0.000502	9.95e-01
DCC mediated attractive signaling	13	9.94e-01	-0.001140	9.95e-01
Glyoxylate metabolism and glycine degradation	24	9.98e-01	-0.000366	9.98e-01

---

Detailed Gene set reports

Neutrophil degranulation

	736
set	Neutrophil degranulation
setSize	458
pANOVA	3.42e-103
s.dist	0.585
p.adjustANOVA	4.67e-100

Top enriched genes

GeneID	Gene Rank
S100A12	9567
S100A9	9562
S100A8	9560
RNASE2	9559
MCEMP1	9558
CTSA	9555
SIRPA	9550
IDH1	9547
CR1	9545
CD93	9540
CD177	9539
MGST1	9532
BST1	9529
CREG1	9521
HP	9518
GCA	9492
TIMP2	9488
CD36	9486
ATP6V0A1	9483
PYGL	9481

Click HERE to show all gene set members

GeneID	Gene Rank
S100A12	9567
S100A9	9562
S100A8	9560
RNASE2	9559
MCEMP1	9558
CTSA	9555
SIRPA	9550
IDH1	9547
CR1	9545
CD93	9540
CD177	9539
MGST1	9532
BST1	9529
CREG1	9521
HP	9518
GCA	9492
TIMP2	9488
CD36	9486
ATP6V0A1	9483
PYGL	9481
PGAM1	9478
CTSD	9475
SERPINB1	9466
ITGAM	9453
LAMTOR1	9450
DOK3	9437
ANPEP	9427
HK3	9425
CKAP4	9420
PGM2	9410
SIGLEC9	9408
PKM	9395
PTAFR	9392
QPCT	9387
FPR1	9379
CDA	9374
MMP9	9370
SDCBP	9367
IMPDH1	9364
PADI2	9362
RAB31	9353
MNDA	9336
CD63	9330
VAT1	9326
GNS	9309
CTSB	9304
QSOX1	9302
LTA4H	9300
GPR84	9292
AGPAT2	9286
FPR2	9282
GRN	9275
ALDOA	9274
CYFIP1	9270
CYSTM1	9266
PLD1	9245
RETN	9241
RAB3D	9231
MAPK14	9219
MGAM	9213
FCAR	9211
C5AR1	9205
SERPINA1	9179
FCN1	9165
CD14	9164
CD55	9157
CLEC4D	9154
SLC11A1	9152
VNN1	9151
TRPM2	9149
SLC2A3	9144
OSCAR	9143
GYG1	9141
NCSTN	9139
CAT	9137
TOM1	9133
NFAM1	9119
ATP6V1D	9118
ATP6V0C	9113
ALOX5	9088
NEU1	9084
VAPA	9073
APAF1	9072
TLR2	9069
BRI3	9064
SELL	9023
CRISPLD2	9022
PRKCD	9012
S100A11	9007
GM2A	9002
CTSZ	9001
CYBB	9000
PRDX6	8986
SERPINB10	8984
TNFAIP6	8970
RAB10	8915
ITGB2	8908
ARG1	8895
LRG1	8891
CYB5R3	8887
FCGR2A	8858
AMPD3	8841
GSN	8805
LAMP2	8803
LILRB3	8793
RAB7A	8775
HEXB	8749
DNAJC5	8746
PYCARD	8734
RAC1	8720
ADAM10	8705
FTL	8698
RAB5C	8688
TOLLIP	8668
PDXK	8664
ARPC5	8653
GLB1	8652
MMP25	8630
LGALS3	8619
CAPN1	8613
PLAC8	8610
ALAD	8605
SNAP23	8578
DNASE1L1	8575
CLEC5A	8574
S100P	8552
RHOG	8544
PSMB7	8535
HBB	8528
PNP	8525
RAB27A	8504
MMP8	8494
PLAUR	8490
ALDH3B1	8489
HEBP2	8478
DNAJC3	8468
P2RX1	8444
DERA	8442
ATP11A	8431
HPSE	8427
TMBIM1	8425
ANXA2	8424
CD68	8421
ADGRG3	8417
GLA	8404
ACAA1	8398
FGR	8397
SIGLEC5	8382
GMFG	8379
ASAH1	8368
CAB39	8364
MOSPD2	8317
CD44	8314
ARL8A	8305
CTSS	8300
CPPED1	8275
RAB3A	8247
RAB6A	8223
PRCP	8222
RHOA	8218
CAP1	8200
FUCA2	8195
IQGAP1	8189
HSPA1A	8178
DNAJC13	8151
FCER1G	8143
PLEKHO2	8138
CD33	8128
ORM1	8082
C3AR1	8067
ATG7	8065
PGLYRP1	8051
LILRB2	8033
GAA	8031
OLFM4	8008
ANO6	8005
TMEM30A	7995
KCMF1	7951
CD53	7939
ATP6AP2	7934
COMMD9	7912
RAB18	7893
TRAPPC1	7887
PSMD6	7881
PGRMC1	7863
DBNL	7859
PSEN1	7843
PTPRJ	7833
ACTR2	7827
CANT1	7826
CMTM6	7818
GLIPR1	7804
SIRPB1	7802
LCN2	7752
COTL1	7749
RNASE3	7744
PECAM1	7743
LAMTOR2	7704
LAMTOR3	7692
UNC13D	7687
ACTR10	7652
DOCK2	7631
LAMP1	7613
TYROBP	7587
CRISP3	7552
OSTF1	7522
MAPK1	7520
NCKAP1L	7516
FUCA1	7508
NAPRT	7506
PSMD2	7470
GUSB	7454
ROCK1	7445
ITGAX	7429
COPB1	7399
VCL	7380
ARSB	7373
MPO	7364
MANBA	7361
AP2A2	7360
TUBB4B	7341
GDI2	7337
RAP1A	7319
ELANE	7303
LAIR1	7301
PSMD1	7283
IGF2R	7270
TCIRG1	7266
CFP	7228
LYZ	7202
FOLR3	7200
GALNS	7183
NBEAL2	7161
SURF4	7147
MVP	7108
RAB14	7090
ATP8B4	7041
CEACAM1	7034
PAFAH1B2	7026
TSPAN14	7007
METTL7A	6999
DYNC1LI1	6992
DDOST	6972
STOM	6963
CEACAM3	6960
VCP	6955
CYBA	6952
PSAP	6909
CSTB	6856
MAN2B1	6854
CXCR1	6844
PRTN3	6822
RAB5B	6801
AP1M1	6788
ERP44	6782
YPEL5	6725
CNN2	6719
DDX3X	6710
CD58	6665
CCT8	6640
HSPA6	6580
BPI	6538
PSMD12	6537
AOC1	6531
HSPA1B	6495
ARMC8	6440
SNAP29	6418
SRP14	6411
GGH	6387
NFKB1	6367
CTSH	6356
PSMD11	6296
ARHGAP9	6288
DEGS1	6287
IQGAP2	6286
TCN1	6281
C6orf120	6267
GPI	6246
TICAM2	6244
NDUFC2	6199
DEFA4	6193
LTF	6182
PTPN6	6176
ATP11B	6172
CHIT1	6164
ITGAV	6133
VPS35L	6132
FABP5	6123
DYNLL1	6049
PPBP	6029
PSMD7	6017
PDAP1	6001
PSMD13	5991
CD59	5964
CPNE3	5955
DEFA1	5953
RNASET2	5952
PGM1	5947
IST1	5945
TNFRSF1B	5916
CXCR2	5851
BIN2	5796
SERPINB6	5793
PTX3	5775
STBD1	5745
ADAM8	5709
FAF2	5634
A1BG	5617
CXCL1	5516
NPC2	5468
XRCC5	5452
PSMA2	5433
SLPI	5421
RAB24	5415
NRAS	5411
TARM1	5384
AZU1	5376
DGAT1	5367
VAMP8	5284
CTSG	5224
ACLY	5214
PTPRN2	5203
SIGLEC14	5150
PLAU	4978
CEACAM8	4935
FTH1	4867
HVCN1	4848
STING1	4844
ABCA13	4730
CEACAM6	4720
CAMP	4713
PSMD3	4693
RAP2C	4677
KRT1	4597
CLEC12A	4566
DYNLT1	4474
B4GALT1	4354
FCGR3B	4340
GHDC	4207
GOLGA7	4109
CSNK2B	3987
SLC15A4	3867
STK11IP	3634
ARSA	3499
SLCO4C1	3445
PSMB1	3422
RAP1B	3331
RAB4B	3231
SLC44A2	2733
PSMD14	2703
MAGT1	2698
PSMC2	2696
CTSC	2547
KPNB1	2491
OLR1	2447
MS4A3	2372
MLEC	2315
PTPRC	2253
CST3	2157
SVIP	2123
SLC2A5	2109
PSMC3	2018
CFD	2016
GSDMD	1976
HGSNAT	1871
NME2	1853
SCAMP1	1834
HSP90AA1	1348
NHLRC3	1267
APEH	1061
HLA-C	1032
NFASC	884
HLA-B	658
TXNDC5	548
RAB44	540
TMEM179B	497
PYGB	484
LRMP	447
ADGRE3	396
EEF2	289
FGL2	275
GSTP1	197
FRK	94
KCNAB2	0
PRDX4	-86
HMGB1	-200
CHI3L1	-634
RAP2B	-691
DIAPH1	-704
DSP	-1230
COMMD3	-1441
LRRC7	-2007
ILF2	-2037
CD300A	-2076
UBR4	-2107
ADGRE5	-2501
HLA-A	-2578
ORM2	-2594
APRT	-2769
AGL	-3177
PFKL	-3284
ALDOC	-3343
MME	-3410
CPNE1	-3422
STK10	-3811
MIF	-3828
HLA-H	-3892
SLC27A2	-3903
PA2G4	-3965
AGA	-4398
XRCC6	-4475
DPP7	-4544
EPX	-4583
SYNGR1	-4703
PIGR	-4739
EEF1A1	-5073
JUP	-5541
PSMA5	-6154
RAB9B	-6471
CAND1	-6550
DSC1	-6597
HSP90AB1	-6702
PTGES2	-6796
PPIA	-6900
B2M	-7019
TUBB	-7078
HRNR	-7225
BST2	-7533
LPCAT1	-7557
PTPRB	-7737
DYNC1H1	-7822
HUWE1	-8044
TMEM63A	-8437
CDK13	-8535
CCT2	-8727
PPIE	-8762
CRACR2A	-9184
CEP290	-9354
IMPDH2	-9608
ENPP4	-9810
ATAD3B	-9936
ORMDL3	-9994
TMC6	-10352
ACTR1B	-10368
HSPA8	-10913
DSN1	-10945
ITGAL	-11015
SPTAN1	-11438
FRMPD3	-11446
TBC1D10C	-11564
NIT2	-11684
ATP8A1	-11780
HMOX2	-11783
RAB37	-11814
CLEC4C	-11862
CD47	-12112
C3	-12243
RHOF	-12291

---

Innate Immune System

	536
set	Innate Immune System
setSize	968
pANOVA	8.43e-85
s.dist	0.369
p.adjustANOVA	5.75e-82

Top enriched genes

GeneID	Gene Rank
WASF1	9568
S100A12	9567
S100A9	9562
S100A8	9560
RNASE2	9559
MCEMP1	9558
CTSA	9555
SIRPA	9550
IDH1	9547
CR1	9545
CD93	9540
CD177	9539
MGST1	9532
BST1	9529
CREG1	9521
HP	9518
CCR2	9503
GCA	9492
TIMP2	9488
CD36	9486

Click HERE to show all gene set members

GeneID	Gene Rank
WASF1	9568
S100A12	9567
S100A9	9562
S100A8	9560
RNASE2	9559
MCEMP1	9558
CTSA	9555
SIRPA	9550
IDH1	9547
CR1	9545
CD93	9540
CD177	9539
MGST1	9532
BST1	9529
CREG1	9521
HP	9518
CCR2	9503
GCA	9492
TIMP2	9488
CD36	9486
ATP6V0A1	9483
PYGL	9481
PGAM1	9478
CTSD	9475
SERPINB1	9466
ITGAM	9453
LAMTOR1	9450
PRKACA	9441
DOK3	9437
ANPEP	9427
HK3	9425
CLU	9423
CKAP4	9420
PGM2	9410
SIGLEC9	9408
NLRC4	9406
RASGRP4	9405
FCGR1A	9397
PKM	9395
PTAFR	9392
QPCT	9387
FPR1	9379
CDA	9374
SIGLEC15	9371
MMP9	9370
SDCBP	9367
NCF4	9365
IMPDH1	9364
PADI2	9362
RAB31	9353
MNDA	9336
TLR8	9335
CD63	9330
VAT1	9326
DUSP3	9324
GRB2	9320
GNS	9309
NKIRAS2	9308
CTSB	9304
ARPC1B	9303
QSOX1	9302
ATP6V1A	9301
LTA4H	9300
ATP6V0D1	9298
GPR84	9292
AGPAT2	9286
FPR2	9282
GRN	9275
ALDOA	9274
CYFIP1	9270
CYSTM1	9266
TLR5	9254
PLD1	9245
RETN	9241
RAB3D	9231
MAPK14	9219
MGAM	9213
FCAR	9211
NCF2	9209
C5AR1	9205
SERPINA1	9179
SIGLEC16	9171
FCN1	9165
CD14	9164
CD55	9157
CLEC4D	9154
SLC11A1	9152
VNN1	9151
TRPM2	9149
SLC2A3	9144
OSCAR	9143
GYG1	9141
NCSTN	9139
CAT	9137
TOM1	9133
UBE2D1	9125
APP	9123
NFAM1	9119
ATP6V1D	9118
ATP6V0C	9113
ALOX5	9088
SYK	9087
NEU1	9084
MAPK3	9078
VAPA	9073
APAF1	9072
TLR2	9069
PIK3CB	9065
BRI3	9064
ACTB	9060
TLR1	9041
C1QC	9025
SELL	9023
CRISPLD2	9022
PRKCD	9012
MAP2K6	9010
S100A11	9007
ATP6V1B2	9005
GM2A	9002
CTSZ	9001
CYBB	9000
HCK	8992
PRDX6	8986
SERPINB10	8984
TLR4	8981
TNFAIP6	8970
MAP2K1	8960
IRAK3	8947
CRK	8941
MYO10	8933
TLR6	8931
ARPC1A	8923
RAB10	8915
ITGB2	8908
LAT2	8902
ARG1	8895
LRG1	8891
CYB5R3	8887
LY96	8871
FCGR2A	8858
AMPD3	8841
ALPK1	8835
NLRP3	8813
GSN	8805
LAMP2	8803
BCL2L1	8798
LILRB3	8793
MAP2K3	8785
RAB7A	8775
HEXB	8749
DNAJC5	8746
PYCARD	8734
CDC34	8728
RAC1	8720
UBE2D3	8710
ADAM10	8705
ATP6V0B	8701
FTL	8698
RAB5C	8688
ACTG1	8671
TOLLIP	8668
PDXK	8664
ATP6V0E1	8662
ARPC5	8653
GLB1	8652
C1QB	8645
MMP25	8630
ATP6V1C1	8628
LGALS3	8619
CAPN1	8613
PLAC8	8610
ALAD	8605
WAS	8596
SNAP23	8578
MEFV	8576
DNASE1L1	8575
CLEC5A	8574
S100P	8552
RHOG	8544
PSMB7	8535
RNF135	8534
HBB	8528
PNP	8525
CAPZA2	8521
RAB27A	8504
PSMD4	8498
MMP8	8494
PLAUR	8490
ALDH3B1	8489
HEBP2	8478
DNAJC3	8468
P2RX1	8444
DERA	8442
ATP11A	8431
HPSE	8427
TMBIM1	8425
ANXA2	8424
CD68	8421
ADGRG3	8417
TXN	8414
GLA	8404
ACAA1	8398
FGR	8397
NOD2	8393
SIGLEC5	8382
GMFG	8379
WASF2	8373
ASAH1	8368
CAB39	8364
CLEC4A	8344
PSME3	8331
MOSPD2	8317
CD44	8314
ARPC3	8309
PPP2CA	8308
ARL8A	8305
CTSS	8300
C5AR2	8286
TRIM25	8276
CPPED1	8275
MAPKAPK3	8255
PAK1	8252
CLEC4E	8250
RAB3A	8247
CFL1	8242
PPP3R1	8240
PAK2	8226
RAB6A	8223
PRCP	8222
RHOA	8218
CAP1	8200
FUCA2	8195
IQGAP1	8189
PSMB5	8188
HSPA1A	8178
PELI2	8166
CAPZA1	8165
DNAJC13	8151
FCER1G	8143
PLEKHO2	8138
CD33	8128
ATP6V1H	8119
ATP6V1E1	8107
GAB2	8100
MYD88	8091
ORM1	8082
C3AR1	8067
ATG7	8065
PGLYRP1	8051
LILRB2	8033
GAA	8031
MEF2A	8030
VAV1	8021
OLFM4	8008
ANO6	8005
TMEM30A	7995
RAF1	7991
CHUK	7959
KCMF1	7951
CD53	7939
ATP6AP2	7934
PSTPIP1	7930
ICAM3	7916
COMMD9	7912
RAB18	7893
ACTR3	7888
TRAPPC1	7887
PSMD6	7881
NLRX1	7880
PGRMC1	7863
DBNL	7859
PSEN1	7843
PTPRJ	7833
CNPY3	7831
ACTR2	7827
CANT1	7826
CMTM6	7818
GLIPR1	7804
SIRPB1	7802
RPS6KA1	7800
CASP9	7784
UBA3	7776
LY86	7774
PPP2CB	7769
PROS1	7763
LCN2	7752
COTL1	7749
RNASE3	7744
PECAM1	7743
PELI3	7736
LYN	7728
PSMD9	7712
LAMTOR2	7704
LAMTOR3	7692
UNC13D	7687
POLR2E	7660
ACTR10	7652
DOCK2	7631
LAMP1	7613
ARPC4	7605
UBE2M	7590
TYROBP	7587
NCKAP1	7562
CRISP3	7552
CDC42	7539
OSTF1	7522
MAPK1	7520
NCKAP1L	7516
FUCA1	7508
NAPRT	7506
TANK	7494
TEC	7488
PSMD2	7470
GUSB	7454
ARPC2	7449
ROCK1	7445
PLD3	7441
NCF1	7433
ITGAX	7429
DOCK1	7413
COPB1	7399
VCL	7380
ARSB	7373
MPO	7364
MANBA	7361
AP2A2	7360
PSMA1	7346
TUBB4B	7341
GDI2	7337
RAP1A	7319
ELANE	7303
LAIR1	7301
PSMD1	7283
CD300LB	7274
IGF2R	7270
PLD2	7268
TCIRG1	7266
PSMB3	7265
MAVS	7231
CFP	7228
LYZ	7202
FOLR3	7200
GALNS	7183
PSMA7	7174
DNM3	7167
NBEAL2	7161
BTK	7156
ABI1	7154
SURF4	7147
MVP	7108
C1QA	7103
PSMC1	7096
RAB14	7090
BRK1	7085
TREM1	7071
TAB2	7070
ATP8B4	7041
CEACAM1	7034
PAFAH1B2	7026
TSPAN14	7007
METTL7A	6999
PPP3CB	6998
DYNC1LI1	6992
DDOST	6972
STOM	6963
CEACAM3	6960
VCP	6955
CYBA	6952
MAP2K4	6948
PSMB6	6927
WASF3	6915
PSAP	6909
RNASE6	6873
CSTB	6856
MAN2B1	6854
CXCR1	6844
NFKBIA	6835
UBE2K	6832
PRTN3	6822
RAB5B	6801
AP1M1	6788
ERP44	6782
MYH9	6772
UBB	6737
CD300E	6736
YPEL5	6725
PSMF1	6724
CNN2	6719
DDX3X	6710
PSMC6	6701
MYO5A	6685
CD58	6665
POLR1D	6651
CARD9	6650
CCT8	6640
PELI1	6596
MUC1	6589
HSPA6	6580
LPO	6576
BPI	6538
PSMD12	6537
AOC1	6531
CLEC6A	6509
HSPA1B	6495
MYO9B	6481
AHCYL1	6475
CTNNB1	6463
CGAS	6459
ARMC8	6440
SNAP29	6418
SRP14	6411
GGH	6387
TICAM1	6380
NFKB1	6367
CTSH	6356
PPP3CA	6327
ELMO1	6324
PSMD11	6296
ARHGAP9	6288
DEGS1	6287
IQGAP2	6286
FBXW11	6282
TCN1	6281
C6orf120	6267
MAP3K8	6262
GPI	6246
TICAM2	6244
DTX4	6230
PDPK1	6209
EP300	6208
NDUFC2	6199
DEFA4	6193
PANX1	6189
LTF	6182
FOS	6179
PTPN6	6176
ATP11B	6172
CHIT1	6164
DNM2	6163
IRAK1	6159
ITGAV	6133
VPS35L	6132
LRRFIP1	6127
FABP5	6123
DYNLL1	6049
PPBP	6029
PSMD7	6017
PDAP1	6001
CASP4	6000
PSMD13	5991
TAX1BP1	5982
PSMA6	5978
CD59	5964
CPNE3	5955
DEFA1	5953
RNASET2	5952
STAT6	5950
ATP6V1F	5949
PGM1	5947
IST1	5945
CD46	5933
BCL10	5931
ITPR2	5919
TNFRSF1B	5916
CXCR2	5851
PSMD8	5845
BIN2	5796
SERPINB6	5793
ATF1	5790
ATP6V1E2	5776
PTX3	5775
WIPF2	5769
FADD	5746
STBD1	5745
TAB1	5711
ADAM8	5709
TIRAP	5700
UBE2V1	5681
FAF2	5634
TNIP2	5630
A1BG	5617
DEFA3	5539
CXCL1	5516
CLEC7A	5515
NPC2	5468
XRCC5	5452
IKBKG	5434
PSMA2	5433
SLPI	5421
RAB24	5415
NRAS	5411
TARM1	5384
PTPN11	5383
AZU1	5376
DGAT1	5367
POLR2L	5362
TKFC	5347
PCBP2	5338
PRKCSH	5300
VAMP8	5284
RAC2	5238
CTSG	5224
ACLY	5214
PTPRN2	5203
MAP3K1	5160
SIGLEC14	5150
PLCG2	5103
CTSK	5077
PIK3R2	5051
ECSIT	4997
PLAU	4978
VAV3	4974
TIFA	4941
CEACAM8	4935
CRCP	4914
FTH1	4867
C4BPA	4852
HVCN1	4848
STING1	4844
IL1B	4830
IKBKE	4779
BIRC2	4749
GRAP2	4746
LIMK1	4741
ABCA13	4730
UBE2D2	4721
CEACAM6	4720
CAMP	4713
PIK3CA	4697
PSMD3	4693
RAP2C	4677
PPP2R1A	4669
POLR2F	4646
EEA1	4631
KRT1	4597
CTSL	4583
CLEC12A	4566
ELMO2	4507
PTK2	4506
C4A	4491
DYNLT1	4474
ATOX1	4439
SEM1	4436
UBC	4421
DUSP6	4367
B4GALT1	4354
SKP1	4349
FCGR3B	4340
RIPK3	4262
GHDC	4207
MAPKAPK2	4176
SHC1	4173
MAPK10	4136
CPN2	4134
UNC93B1	4133
GOLGA7	4109
PSMB2	4103
CASP1	4086
ATP6V1G1	3989
CSNK2B	3987
JUN	3964
C2	3960
MAPK11	3955
C5	3932
C4B	3927
SOCS1	3886
SLC15A4	3867
RELB	3767
KRAS	3760
MAPK13	3704
STK11IP	3634
DNM1	3526
PSMD5	3507
ARSA	3499
DDX41	3464
CREBBP	3460
SLCO4C1	3445
PSMB1	3422
P2RX7	3420
MYO1C	3351
RAP1B	3331
RAB4B	3231
RPS6KA2	3177
TAB3	3165
TBK1	3159
RPS6KA3	3012
PI3	2860
SLC44A2	2733
PSMD14	2703
MAGT1	2698
PSMC2	2696
PSMB4	2552
CTSC	2547
KPNB1	2491
TRIM21	2467
MAP3K7	2453
OLR1	2447
PPP2R5D	2440
EPPIN	2431
MS4A3	2372
MLEC	2315
PTPRC	2253
CST3	2157
SVIP	2123
ATF2	2110
SLC2A5	2109
HSP90B1	2086
PSMC3	2018
CFD	2016
GSDMD	1976
UBE2N	1951
HGSNAT	1871
NME2	1853
SCAMP1	1834
MAP2K7	1647
PSMD10	1646
PIK3C3	1626
SUGT1	1576
ATG5	1445
NOS1	1401
ITCH	1394
HSP90AA1	1348
AGER	1309
VRK3	1293
NHLRC3	1267
UBA52	1071
APEH	1061
RIPK2	1042
ELK1	1040
HLA-C	1032
DHX9	984
NFASC	884
IGHV1-2	679
HLA-B	658
ATP7A	647
WIPF1	581
TXNDC5	548
RAB44	540
TMEM179B	497
PYGB	484
LRMP	447
ADGRE3	396
NKIRAS1	387
NCKIPSD	320
EEF2	289
WASL	283
FGL2	275
ABL1	229
GSTP1	197
IGHV2-5	174
IGHV3-53	122
FRK	94
IFI16	46
KCNAB2	0
IGLC3	-37
PRDX4	-86
NFKBIB	-88
IGKV1-39	-173
BAIAP2	-179
HMGB1	-200
TRAF6	-241
PPP2R1B	-246
MEF2C	-319
IGKV5-2	-357
IGLV5-45	-419
IGHV3-7	-437
IGKV3-11	-446
PSMA4	-538
IGHV3-48	-583
CHI3L1	-634
TLR7	-655
RAP2B	-691
DIAPH1	-704
IGLV2-8	-740
CD180	-761
ATG12	-784
IGHV1-46	-823
NFKB2	-865
MAPK12	-946
PSMC5	-948
IGKV1-5	-984
IGKV1-16	-990
IGHV3-23	-1042
LCP2	-1167
IGKV1D-39	-1172
TREX1	-1227
DSP	-1230
IGKV2D-28	-1291
MAPK7	-1294
IGLV7-46	-1341
CREB1	-1382
IGLV10-54	-1414
IGHV3-13	-1436
COMMD3	-1441
IGLV2-18	-1472
IGKV1-33	-1613
IGLV1-36	-1670
AIM2	-1685
NOS3	-1718
IGKV2-30	-1725
IGLV4-69	-1768
POLR2K	-1792
RELA	-1807
IGHV1-69	-1811
IGHV4-59	-1969
LRRC7	-2007
IGLV3-19	-2016
IGKV3-15	-2034
ILF2	-2037
IGHV3-11	-2041
CALM1	-2048
VTN	-2057
CD300A	-2076
IGHV4-34	-2080
UBR4	-2107
IGHV3-30	-2221
ATP6V1C2	-2222
MUCL1	-2297
PGLYRP2	-2301
C1S	-2334
CASP2	-2478
ADGRE5	-2501
POLR3K	-2543
HLA-A	-2578
ORM2	-2594
IGLV2-23	-2597
MUC4	-2624
IGKV4-1	-2625
C4BPB	-2678
APRT	-2769
IGLV2-11	-2782
IGKV1-17	-2799
CTSV	-2816
POLR2H	-2817
IGKV3-20	-2824
IGLV6-57	-2876
TLR10	-2899
IGHV3-33	-2989
MUC6	-3012
IGLV1-44	-3076
PSMB8	-3080
AGL	-3177
IGHV2-70	-3195
DUSP7	-3253
PIN1	-3272
PFKL	-3284
MUC16	-3285
HRAS	-3335
ALDOC	-3343
HTN1	-3350
IGHG3	-3394
MME	-3410
CPNE1	-3422
CASP10	-3491
CFB	-3571
AAMP	-3695
IGHV4-39	-3735
CD19	-3769
STK10	-3811
MIF	-3828
CR2	-3883
HLA-H	-3892
SLC27A2	-3903
PA2G4	-3965
IGKV3D-20	-4012
PIK3R4	-4040
VAV2	-4073
IGLV3-1	-4093
IGLV7-43	-4100
IGLV1-40	-4105
PAK3	-4194
IGKC	-4212
IGLV3-25	-4239
AGA	-4398
IGLV1-51	-4413
HLA-E	-4448
IGLV3-21	-4455
XRCC6	-4475
BCL2	-4480
DPP7	-4544
RBSN	-4574
EPX	-4583
MUC5B	-4618
LEAP2	-4665
SYNGR1	-4703
LGMN	-4724
PIGR	-4739
IGLC7	-4779
BTRC	-4932
S100B	-5025
EEF1A1	-5073
OTUD5	-5121
MASP2	-5154
IGHE	-5174
IGKV1-12	-5223
POLR3F	-5248
DHX36	-5253
IKBKB	-5290
TRAF3	-5296
PSMA3	-5314
CD4	-5320
IGLC2	-5370
CLEC10A	-5371
IGLV8-61	-5395
POLR3G	-5426
JUP	-5541
IGLC1	-5548
IGHG1	-5669
SOS1	-5714
CFH	-5728
PSMB10	-5768
IGKV2-28	-5778
MUC20	-5791
IGLV1-47	-5810
TLR9	-5909
IGLV3-27	-5935
NLRP1	-5972
PSME4	-6099
PSMA5	-6154
ITLN1	-6277
PDZD11	-6343
DUSP4	-6432
RAB9B	-6471
PLPP5	-6508
CAND1	-6550
DSC1	-6597
NF2	-6614
HSP90AB1	-6702
IGHG4	-6718
PTGES2	-6796
RPS27A	-6894
PPIA	-6900
SIKE1	-6959
B2M	-7019
TUBB	-7078
CCR6	-7086
IGHG2	-7087
MAPK9	-7182
HRNR	-7225
POLR3A	-7359
UBA7	-7455
IGLV3-12	-7472
POLR3B	-7484
BST2	-7533
POLR3C	-7545
ITPR1	-7553
LPCAT1	-7557
PSMA8	-7559
POLR3GL	-7616
PTPRB	-7737
DYNC1H1	-7822
MRE11	-7888
PRKCE	-8024
HUWE1	-8044
RASGRP2	-8137
S100A1	-8267
KIR2DS4	-8380
IGLV2-14	-8416
TMEM63A	-8437
IRF3	-8479
CDK13	-8535
CCT2	-8727
PPIE	-8762
IRF7	-8889
TRIM56	-8899
SRC	-9011
CYLD	-9037
CRACR2A	-9184
CD209	-9237
ATP6V1G2	-9275
PSMC4	-9306
NFATC1	-9315
CEP290	-9354
CD81	-9413
IMPDH2	-9608
MAPK8	-9646
IRAK2	-9718
PIK3R1	-9725
KLRC2	-9779
TXNIP	-9792
ENPP4	-9810
C1R	-9909
ATAD3B	-9936
ITPR3	-9955
ORMDL3	-9994
PSME1	-10138
NLRC5	-10156
PRKDC	-10173
POLR3H	-10263
TMC6	-10352
RNF216	-10357
ACTR1B	-10368
CYFIP2	-10387
POLR1C	-10390
PSME2	-10415
PLCG1	-10473
SIGIRR	-10688
MALT1	-10701
BIRC3	-10830
MUC12	-10883
ABI2	-10893
HSPA8	-10913
DSN1	-10945
ITGAL	-11015
ITK	-11066
POLR3E	-11083
TNFAIP3	-11131
MS4A2	-11156
RIPK1	-11184
RNF125	-11320
PSMB9	-11362
TRIM32	-11375
LAT	-11376
CD3G	-11409
UBE2L6	-11415
SPTAN1	-11438
SERPING1	-11444
FRMPD3	-11446
CASP8	-11463
CUL1	-11467
ATP6V0E2	-11475
MAP3K14	-11478
NCK1	-11488
LCK	-11492
IFIH1	-11499
GNLY	-11505
TLR3	-11538
POLR3D	-11556
TBC1D10C	-11564
TRAF2	-11594
RPS6KA5	-11616
FCGR3A	-11661
NIT2	-11684
C8G	-11697
FYN	-11758
TXK	-11762
ATP8A1	-11780
HMOX2	-11783
RAB37	-11814
GZMM	-11815
RASGRP1	-11817
PRKACB	-11857
CLEC4C	-11862
DHX58	-11880
FCER1A	-11937
SARM1	-11973
DDX58	-11974
ICAM2	-11994
PLA2G6	-12020
CARD11	-12035
PRKCQ	-12039
NLRC3	-12056
KLRD1	-12088
ISG15	-12099
CD47	-12112
PTPN4	-12133
NFATC3	-12139
YES1	-12143
ATP6V0A2	-12193
KLRK1	-12224
HERC5	-12225
NOD1	-12234
NFATC2	-12236
C3	-12243
ZBP1	-12280
RHOF	-12291
CD247	-12295
PLD4	-12302

---

Immune System

	519
set	Immune System
setSize	1894
pANOVA	1.88e-46
s.dist	0.198
p.adjustANOVA	8.53e-44

Top enriched genes

GeneID	Gene Rank
CSF2RA	9574
WASF1	9568
S100A12	9567
S100A9	9562
S100A8	9560
RNASE2	9559
MCEMP1	9558
CTSA	9555
SIRPA	9550
VAMP7	9549
IDH1	9547
CR1	9545
CD93	9540
CD177	9539
MGST1	9532
BST1	9529
SOCS3	9526
CREG1	9521
HP	9518
TALDO1	9505

Click HERE to show all gene set members

GeneID	Gene Rank
CSF2RA	9574.0
WASF1	9568.0
S100A12	9567.0
S100A9	9562.0
S100A8	9560.0
RNASE2	9559.0
MCEMP1	9558.0
CTSA	9555.0
SIRPA	9550.0
VAMP7	9549.0
IDH1	9547.0
CR1	9545.0
CD93	9540.0
CD177	9539.0
MGST1	9532.0
BST1	9529.0
SOCS3	9526.0
CREG1	9521.0
HP	9518.0
TALDO1	9505.0
CCR2	9503.0
GCA	9492.0
SERPINB2	9491.0
TIMP2	9488.0
CD36	9486.0
ATP6V0A1	9483.0
PYGL	9481.0
PGAM1	9478.0
CTSD	9475.0
FBXO9	9467.0
SERPINB1	9466.0
FBXL5	9458.0
ITGAM	9453.0
LAMTOR1	9450.0
PRKACA	9441.0
DOK3	9437.0
LTBR	9434.0
IL1RN	9432.0
ANPEP	9427.0
HK3	9425.0
CLU	9423.0
CKAP4	9420.0
CA1	9414.0
PGM2	9410.0
SIGLEC9	9408.0
NLRC4	9406.0
RASGRP4	9405.0
VIM	9399.0
FCGR1A	9397.0
IL1R2	9396.0
PKM	9395.0
PTAFR	9392.0
LMNB1	9391.0
QPCT	9387.0
IL10	9385.0
FPR1	9379.0
CDA	9374.0
SIGLEC15	9371.0
MMP9	9370.0
SDCBP	9367.0
NCF4	9365.0
IMPDH1	9364.0
PADI2	9362.0
RAB31	9353.0
LILRA6	9350.0
TNFRSF1A	9347.0
AP1S1	9338.0
MNDA	9336.0
TLR8	9335.0
CD63	9330.0
VAT1	9326.0
MAOA	9325.0
DUSP3	9324.0
GRB2	9320.0
GNS	9309.0
NKIRAS2	9308.0
CTSB	9304.0
ARPC1B	9303.0
QSOX1	9302.0
ATP6V1A	9301.0
LTA4H	9300.0
BCL6	9299.0
ATP6V0D1	9298.0
IFNGR2	9297.0
GPR84	9292.0
AGPAT2	9286.0
FPR2	9282.0
GRN	9275.0
ALDOA	9274.0
UBE2J1	9272.0
CYFIP1	9270.0
CYSTM1	9266.0
IFNGR1	9257.0
TLR5	9254.0
KLHL2	9252.0
SPTB	9250.0
IL17RA	9248.0
PLD1	9245.0
RETN	9241.0
RAB3D	9231.0
MAPK14	9219.0
MGAM	9213.0
FCAR	9211.0
NCF2	9209.0
C5AR1	9205.0
IL10RB	9185.0
SERPINA1	9179.0
SIGLEC16	9171.0
FCGR1B	9168.0
FCN1	9165.0
CD14	9164.0
RAP1GAP	9159.0
DCTN2	9158.0
CD55	9157.0
CLEC4D	9154.0
SLC11A1	9152.0
VNN1	9151.0
TRPM2	9149.0
SLC2A3	9144.0
OSCAR	9143.0
GYG1	9141.0
NCSTN	9139.0
CAT	9137.0
TOM1	9133.0
UBE2D1	9125.0
APP	9123.0
NFAM1	9119.0
ATP6V1D	9118.0
LILRA5	9117.0
INPPL1	9115.0
ATP6V0C	9113.0
GSTO1	9089.0
ALOX5	9088.0
SYK	9087.0
NEU1	9084.0
ARF1	9083.0
MAPK3	9078.0
VAPA	9073.0
APAF1	9072.0
DLG4	9070.0
TLR2	9069.0
STXBP2	9067.0
FKBP1A	9066.0
PIK3CB	9065.0
BRI3	9064.0
ACTB	9060.0
LILRA2	9058.0
CLTC	9056.0
TLR1	9041.0
TGFA	9031.0
IL1R1	9030.0
C1QC	9025.0
SELL	9023.0
CRISPLD2	9022.0
LILRB4	9020.0
KL	9019.0
PRKCD	9012.0
MAP2K6	9010.0
S100A11	9007.0
ATP6V1B2	9005.0
GM2A	9002.0
CTSZ	9001.0
CYBB	9000.0
HCK	8992.0
TRIM71	8989.0
PRDX6	8986.0
SERPINB10	8984.0
TLR4	8981.0
TNFAIP6	8970.0
PVR	8966.0
MAP2K1	8960.0
RHOU	8950.0
IRAK3	8947.0
ITGA2B	8942.0
CRK	8941.0
MYO10	8933.0
TLR6	8931.0
ARPC1A	8923.0
F13A1	8919.0
ZDHHC9	8918.0
RAB10	8915.0
ITGB2	8908.0
LAT2	8902.0
ARG1	8895.0
LRG1	8891.0
CYB5R3	8887.0
CD300C	8876.0
NUP58	8872.0
LY96	8871.0
MKRN1	8864.0
FCGR2A	8858.0
CCR1	8857.0
HGF	8856.0
APBB1IP	8849.0
AMPD3	8841.0
ALPK1	8835.0
CEBPD	8826.0
NLRP3	8813.0
GSN	8805.0
LAMP2	8803.0
BCL2L1	8798.0
CSF3R	8795.0
LILRB3	8793.0
MAP2K3	8785.0
RAB7A	8775.0
MARK3	8774.0
HEXB	8749.0
DNAJC5	8746.0
AP1B1	8741.0
PYCARD	8734.0
FBXL19	8733.0
FOXO3	8729.0
CDC34	8728.0
RAC1	8720.0
UBE2D3	8710.0
ADAM10	8705.0
ATP6V0B	8701.0
FTL	8698.0
RAB5C	8688.0
AP2M1	8673.0
ACTG1	8671.0
TOLLIP	8668.0
PDXK	8664.0
ATP6V0E1	8662.0
TRAF7	8658.0
SIAH2	8657.0
ARPC5	8653.0
GLB1	8652.0
C1QB	8645.0
MMP25	8630.0
ATP6V1C1	8628.0
LGALS3	8619.0
CAPN1	8613.0
PLAC8	8610.0
ALAD	8605.0
WAS	8596.0
TIMP1	8594.0
STX3	8585.0
SNAP23	8578.0
MEFV	8576.0
DNASE1L1	8575.0
CLEC5A	8574.0
UBE2R2	8564.0
TLN1	8554.0
S100P	8552.0
RHOG	8544.0
PSMB7	8535.0
RNF135	8534.0
HBB	8528.0
PNP	8525.0
IFNAR1	8523.0
CAPZA2	8521.0
ARRB2	8517.0
PTEN	8516.0
RAB27A	8504.0
PSMD4	8498.0
MMP8	8494.0
PLAUR	8490.0
ALDH3B1	8489.0
RNF130	8485.0
HEBP2	8478.0
RNF41	8473.0
DNAJC3	8468.0
CD99	8467.0
EIF4G3	8454.0
P4HB	8452.0
KIF3C	8451.0
P2RX1	8444.0
DERA	8442.0
RILP	8440.0
TRIM8	8438.0
ATP11A	8431.0
HPSE	8427.0
TMBIM1	8425.0
ANXA2	8424.0
RNF217	8422.0
CD68	8421.0
LCP1	8419.0
ADGRG3	8417.0
TXN	8414.0
GLA	8404.0
CLTA	8402.0
ACAA1	8398.0
FGR	8397.0
NOD2	8393.0
UBE2J2	8389.0
DCTN4	8385.0
SIGLEC5	8382.0
GMFG	8379.0
WASF2	8373.0
ASAH1	8368.0
ITGB3	8367.0
CAB39	8364.0
SOS2	8350.0
MAP3K3	8349.0
CLEC4A	8344.0
JAK3	8337.0
PSME3	8331.0
TNFSF13	8324.0
IRS2	8323.0
MOSPD2	8317.0
CD44	8314.0
ARPC3	8309.0
PPP2CA	8308.0
ARL8A	8305.0
UBAC1	8301.0
CTSS	8300.0
FN1	8294.0
C5AR2	8286.0
TRIM25	8276.0
CPPED1	8275.0
EGF	8267.0
MAPKAPK3	8255.0
PAK1	8252.0
CLEC4E	8250.0
NECTIN2	8249.0
RAB3A	8247.0
CFL1	8242.0
PPP3R1	8240.0
IL6R	8229.0
PAK2	8226.0
RAB6A	8223.0
PRCP	8222.0
RHOA	8218.0
CAP1	8200.0
HMOX1	8196.0
FUCA2	8195.0
IQGAP1	8189.0
PSMB5	8188.0
HSPA1A	8178.0
PELI2	8166.0
CAPZA1	8165.0
STAT3	8152.0
DNAJC13	8151.0
KIF5B	8144.0
FCER1G	8143.0
PLEKHO2	8138.0
JAML	8137.0
VASP	8136.0
SEC24D	8130.0
CD33	8128.0
PTPN12	8125.0
VAMP3	8121.0
ATP6V1H	8119.0
ATP6V1E1	8107.0
GAB2	8100.0
MYD88	8091.0
ORM1	8082.0
EIF4G1	8081.0
AP2S1	8080.0
C3AR1	8067.0
ATG7	8065.0
CAPZB	8057.0
PGLYRP1	8051.0
LYPLA1	8039.0
LILRB2	8033.0
ICAM5	8032.0
GAA	8031.0
MEF2A	8030.0
VAV1	8021.0
NUP214	8011.0
PTK2B	8010.0
OLFM4	8008.0
ANO6	8005.0
SIGLEC7	7997.0
TMEM30A	7995.0
RAF1	7991.0
ADAM17	7980.0
RNF7	7977.0
NEDD4L	7972.0
TREML1	7971.0
CHUK	7959.0
KCMF1	7951.0
CD53	7939.0
ATP6AP2	7934.0
UBE2W	7932.0
PSTPIP1	7930.0
ICAM3	7916.0
COMMD9	7912.0
RAB18	7893.0
ACTR3	7888.0
TRAPPC1	7887.0
PSMD6	7881.0
NLRX1	7880.0
PGRMC1	7863.0
DBNL	7859.0
OSM	7854.0
RNASEL	7849.0
PSEN1	7843.0
WSB1	7840.0
PIK3AP1	7836.0
PTPRJ	7833.0
CNPY3	7831.0
ACTR2	7827.0
CANT1	7826.0
CMTM6	7818.0
UBE2H	7815.0
PIM1	7806.0
GLIPR1	7804.0
SIRPB1	7802.0
RPS6KA1	7800.0
FSCN1	7797.0
SPTA1	7785.0
CASP9	7784.0
NPEPPS	7777.0
UBA3	7776.0
LY86	7774.0
PPP2CB	7769.0
CSF2RB	7764.0
PROS1	7763.0
LCN2	7752.0
COTL1	7749.0
RNASE3	7744.0
PECAM1	7743.0
PELI3	7736.0
LYN	7728.0
SEC24A	7716.0
PSMD9	7712.0
RNF144B	7710.0
MAP3K11	7707.0
LAMTOR2	7704.0
LAMTOR3	7692.0
ZNRF1	7691.0
UNC13D	7687.0
EIF4E3	7683.0
LILRA1	7671.0
POLR2E	7660.0
LILRB5	7658.0
ACTR10	7652.0
ELOC	7637.0
PTPN2	7634.0
DOCK2	7631.0
DYNC1I2	7629.0
LAMP1	7613.0
UBE2L3	7612.0
LRRC41	7609.0
ARPC4	7605.0
RGL1	7604.0
CBL	7599.0
UBE2M	7590.0
TYROBP	7587.0
ELOB	7586.0
FBXO7	7577.0
NCKAP1	7562.0
CRISP3	7552.0
EIF4A1	7550.0
RGL2	7547.0
CDC42	7539.0
PJA2	7536.0
ANXA1	7530.0
OSTF1	7522.0
MAPK1	7520.0
SIGLEC11	7518.0
NCKAP1L	7516.0
IFI30	7511.0
FUCA1	7508.0
NAPRT	7506.0
TANK	7494.0
TEC	7488.0
KLC3	7479.0
PSMD2	7470.0
UBE2F	7462.0
GUSB	7454.0
ARPC2	7449.0
ROCK1	7445.0
PLD3	7441.0
PIAS1	7434.0
NCF1	7433.0
IL4R	7432.0
TNFSF12	7430.0
ITGAX	7429.0
SEC23A	7416.0
RNF182	7415.0
DOCK1	7413.0
EIF4E2	7407.0
HIF1A	7404.0
FRS3	7402.0
COPB1	7399.0
IL18	7395.0
VEGFA	7389.0
DCTN6	7382.0
VCL	7380.0
ARSB	7373.0
EIF4A3	7369.0
SHOC2	7365.0
MPO	7364.0
CD1D	7362.0
MANBA	7361.0
AP2A2	7360.0
IL1RAP	7349.0
PSMA1	7346.0
TUBB4B	7341.0
GDI2	7337.0
RAP1A	7319.0
UBE2A	7315.0
ELANE	7303.0
LAIR1	7301.0
PSMD1	7283.0
TRIM10	7277.0
CD300LB	7274.0
IGF2R	7270.0
PLD2	7268.0
TCIRG1	7266.0
PSMB3	7265.0
IL27	7244.0
LILRB1	7242.0
MAVS	7231.0
CFP	7228.0
CLEC4G	7226.0
FLT3	7222.0
MMP1	7209.0
LYZ	7202.0
FOLR3	7200.0
TYK2	7192.0
UBA1	7187.0
GALNS	7183.0
PSMA7	7174.0
MCL1	7168.0
DNM3	7167.0
NBEAL2	7161.0
BTK	7156.0
ABI1	7154.0
SURF4	7147.0
SIGLEC10	7132.0
UBE2B	7129.0
SEC61B	7125.0
HSPA5	7118.0
MVP	7108.0
C1QA	7103.0
PSMC1	7096.0
PPP1CB	7093.0
RAB14	7090.0
ACTR1A	7088.0
PILRA	7087.0
BRK1	7085.0
TREM1	7071.0
TAB2	7070.0
PRKCB	7056.0
DUSP1	7048.0
ATP8B4	7041.0
TNFRSF12A	7036.0
CEACAM1	7034.0
PAFAH1B2	7026.0
STAT5B	7011.0
TSPAN14	7007.0
ITGB5	7004.0
EIF4G2	7001.0
METTL7A	6999.0
PPP3CB	6998.0
DYNC1LI1	6992.0
STAT5A	6983.0
TRIP12	6977.0
SUMO1	6973.0
DDOST	6972.0
STOM	6963.0
CEACAM3	6960.0
TNFSF13B	6959.0
VCP	6955.0
CYBA	6952.0
MAP2K4	6948.0
PSMB6	6927.0
CUL3	6924.0
SPRED2	6917.0
RAPGEF2	6916.0
WASF3	6915.0
PSAP	6909.0
MAP2K2	6906.0
RNF123	6899.0
JUNB	6889.0
RNASE6	6873.0
PPP2R5B	6870.0
PRKG1	6867.0
PITPNA	6864.0
IL19	6862.0
RNF19B	6857.0
CSTB	6856.0
MAN2B1	6854.0
UBE2E1	6853.0
CXCR1	6844.0
CD300LD	6838.0
NFKBIA	6835.0
UBE2K	6832.0
PRTN3	6822.0
RAB5B	6801.0
ICAM1	6797.0
AP1M1	6788.0
ERP44	6782.0
H3C15	6780.5
IFNAR2	6775.0
MYH9	6772.0
FBXO11	6747.0
UBB	6737.0
CD300E	6736.0
YPEL5	6725.0
PSMF1	6724.0
CNN2	6719.0
DDX3X	6710.0
PSMC6	6701.0
MYO5A	6685.0
CD58	6665.0
POLR1D	6651.0
CARD9	6650.0
CCT8	6640.0
BTNL8	6638.0
FBXW2	6635.0
PTPN9	6633.0
CD300LF	6631.0
AP2A1	6628.0
VWF	6607.0
PELI1	6596.0
MUC1	6589.0
HSPA6	6580.0
LPO	6576.0
AREL1	6569.0
KBTBD7	6566.0
SAR1B	6562.0
BPI	6538.0
PSMD12	6537.0
AOC1	6531.0
TREML4	6525.0
SEC61A1	6517.0
IRF2	6511.0
CLEC6A	6509.0
BATF	6501.0
HSPA1B	6495.0
RCHY1	6483.0
MYO9B	6481.0
AHCYL1	6475.0
CTNNB1	6463.0
TREML2	6462.0
CGAS	6459.0
IRF5	6447.0
ARMC8	6440.0
SAMHD1	6437.0
SNAP29	6418.0
CALR	6415.0
SRP14	6411.0
YWHAB	6398.0
GGH	6387.0
TICAM1	6380.0
NFKB1	6367.0
CTSH	6356.0
PPP1CC	6334.0
NEDD4	6330.0
PPP3CA	6327.0
ELMO1	6324.0
ASB7	6322.0
PSMD11	6296.0
ARHGAP9	6288.0
DEGS1	6287.0
IQGAP2	6286.0
RGL3	6283.0
FBXW11	6282.0
TCN1	6281.0
UBE3C	6272.0
C6orf120	6267.0
MAP3K8	6262.0
ANAPC11	6249.0
GPI	6246.0
TICAM2	6244.0
DTX4	6230.0
SH3KBP1	6227.0
PDPK1	6209.0
EP300	6208.0
NDUFC2	6199.0
DEFA4	6193.0
PANX1	6189.0
LTF	6182.0
FOS	6179.0
PTPN6	6176.0
ATP11B	6172.0
CHIT1	6164.0
DNM2	6163.0
IRAK1	6159.0
FNTB	6148.0
ITGAV	6133.0
VPS35L	6132.0
LRRFIP1	6127.0
FABP5	6123.0
ORAI2	6102.0
PIK3CD	6096.0
DCTN3	6080.0
DYNLL1	6049.0
PPBP	6029.0
PSMD7	6017.0
IFITM2	6006.0
PDGFRA	6002.0
PDAP1	6001.0
CASP4	6000.0
PSMD13	5991.0
PPP2R5A	5985.0
TAX1BP1	5982.0
PSMA6	5978.0
CD59	5964.0
CPNE3	5955.0
DEFA1	5953.0
RNASET2	5952.0
STAT6	5950.0
ATP6V1F	5949.0
PGM1	5947.0
IST1	5945.0
PTPN18	5944.0
SEC22B	5939.0
CD46	5933.0
BCL10	5931.0
ITPR2	5919.0
TNFRSF1B	5916.0
RANBP9	5914.0
UBE2Q1	5866.0
CXCR2	5851.0
PSMD8	5845.0
GRIN2D	5844.0
RNF111	5821.0
SEC13	5820.0
PTPN1	5797.0
BIN2	5796.0
SERPINB6	5793.0
ATF1	5790.0
ATP6V1E2	5776.0
PTX3	5775.0
WIPF2	5769.0
MGRN1	5764.0
FADD	5746.0
STBD1	5745.0
GAB1	5723.0
TAB1	5711.0
ADAM8	5709.0
TIRAP	5700.0
PPM1B	5693.0
YWHAZ	5687.0
UBE2V1	5681.0
FAF2	5634.0
TNIP2	5630.0
A1BG	5617.0
KLC1	5596.0
FBXL13	5592.0
KIF23	5584.0
FBXL4	5572.0
MSN	5556.0
RLIM	5540.0
DEFA3	5539.0
TNFRSF8	5528.0
CANX	5526.0
CXCL1	5516.0
CLEC7A	5515.0
CXCL2	5509.0
AREG	5494.0
PDGFA	5484.0
NPC2	5468.0
XRCC5	5452.0
IKBKG	5434.0
PSMA2	5433.0
SLPI	5421.0
RAB24	5415.0
NRAS	5411.0
DAPP1	5398.0
TARM1	5384.0
PTPN11	5383.0
AZU1	5376.0
DGAT1	5367.0
POLR2L	5362.0
BRAP	5352.0
TKFC	5347.0
PCBP2	5338.0
PDE6D	5327.0
PRKCSH	5300.0
CSK	5285.0
VAMP8	5284.0
TRIM34	5246.0
RAC2	5238.0
CTSG	5224.0
ACLY	5214.0
PTPRN2	5203.0
TGFB1	5201.0
IL13RA1	5174.0
UBE2C	5168.0
KIF20A	5165.0
MAP3K1	5160.0
KLHL5	5154.0
RAE1	5152.0
SIGLEC14	5150.0
DCTN1	5143.0
MAPKAP1	5130.0
PLCG2	5103.0
UBE2E3	5089.0
CTSK	5077.0
KPNA4	5074.0
KLHL21	5069.0
PIK3R2	5051.0
UBE2G1	5016.0
KEAP1	5003.0
ECSIT	4997.0
CISH	4988.0
PLAU	4978.0
VAV3	4974.0
ASB8	4973.0
HERC4	4964.0
TIFA	4941.0
CEACAM8	4935.0
CRCP	4914.0
FBXL20	4911.0
CNTF	4904.0
LRSAM1	4895.0
EIF4E	4892.0
HBEGF	4878.0
HECW2	4874.0
FTH1	4867.0
C4BPA	4852.0
HVCN1	4848.0
STING1	4844.0
SEC61G	4837.0
IL1B	4830.0
UBE2S	4810.0
SMARCA4	4789.0
IKBKE	4779.0
FBXO30	4752.0
BIRC2	4749.0
GRAP2	4746.0
LIMK1	4741.0
ABCA13	4730.0
UBE2D2	4721.0
CEACAM6	4720.0
CAMP	4713.0
PIK3CA	4697.0
PSMD3	4693.0
RAP2C	4677.0
PPP2R1A	4669.0
POLR2F	4646.0
EEA1	4631.0
HAVCR2	4624.0
LONRF1	4604.0
KRT1	4597.0
CTSL	4583.0
CLEC12A	4566.0
NUP50	4544.0
FBXL15	4533.0
ELMO2	4507.0
PTK2	4506.0
SHC2	4499.0
C4A	4491.0
DYNLT1	4474.0
SOD2	4458.0
ATOX1	4439.0
CDKN1A	4438.0
SEM1	4436.0
KCTD6	4434.0
UBC	4421.0
PTGS2	4402.0
RNF138	4394.0
EBI3	4388.0
RNF14	4383.0
CTF1	4370.0
DUSP6	4367.0
B4GALT1	4354.0
SKP1	4349.0
FCGR3B	4340.0
IL18R1	4330.0
SP100	4293.0
RIPK3	4262.0
DYNC1LI2	4253.0
DYNC1I1	4211.0
GHDC	4207.0
MAPKAPK2	4176.0
SHC1	4173.0
PDIA3	4172.0
CD101	4165.0
UBR2	4140.0
MAPK10	4136.0
CPN2	4134.0
UNC93B1	4133.0
SQSTM1	4123.0
KSR1	4113.0
GOLGA7	4109.0
PSMB2	4103.0
PAG1	4088.0
CDC20	4087.0
CASP1	4086.0
BIRC5	4082.0
NDN	4057.0
SHC3	4054.0
AP1G1	4052.0
RBX1	4039.0
FBXL8	4029.0
SIPA1	4021.0
NRG1	4018.0
STIM1	4011.0
IL6ST	3996.0
ATP6V1G1	3989.0
RNF6	3988.0
CSNK2B	3987.0
CRKL	3986.0
HNRNPF	3972.0
JUN	3964.0
C2	3960.0
MAPK11	3955.0
SIGLEC12	3940.0
C5	3932.0
C4B	3927.0
SOCS1	3886.0
SLC15A4	3867.0
WDR83	3802.0
KIF3B	3773.0
RELB	3767.0
KIF4A	3763.0
KRAS	3760.0
VHL	3742.0
MAPK13	3704.0
TCP1	3686.0
FGF2	3660.0
AKT1	3656.0
SEC24B	3655.0
STK11IP	3634.0
REL	3592.0
FBXO17	3537.0
DNM1	3526.0
PSMD5	3507.0
ARSA	3499.0
UBA6	3490.0
IL27RA	3474.0
DDX41	3464.0
CREBBP	3460.0
SLCO4C1	3445.0
PSMB1	3422.0
P2RX7	3420.0
TNFSF4	3414.0
HNRNPA2B1	3406.0
FBXL18	3388.0
ASB13	3383.0
MYO1C	3351.0
RAP1B	3331.0
ASB1	3318.0
RAB4B	3231.0
SOCS5	3202.0
MRC1	3187.0
RPS6KA2	3177.0
TAB3	3165.0
TBK1	3159.0
NUP37	3153.0
NUP98	3124.0
NF1	3113.0
TAPBP	3075.0
BLMH	3071.0
UBE3A	3047.0
CDC26	3013.0
RPS6KA3	3012.0
RNF114	3010.0
UBE2V2	2997.0
POMC	2971.0
EGR1	2965.0
ANAPC13	2930.0
RACGAP1	2921.0
PSPN	2902.0
LGALS9	2869.0
PI3	2860.0
SLC44A2	2733.0
PSMD14	2703.0
MAGT1	2698.0
PSMC2	2696.0
RALA	2686.0
ARAF	2680.0
IRF8	2671.0
IL1RL1	2644.0
JAK2	2599.0
IL15RA	2586.0
EPGN	2579.0
ANGPT1	2578.0
CUL2	2559.0
PSMB4	2552.0
CTSC	2547.0
COL1A2	2518.0
KPNB1	2491.0
TRIM21	2467.0
TRIM38	2454.0
MAP3K7	2453.0
FBXO40	2452.0
OLR1	2447.0
PPP2R5D	2440.0
EPPIN	2431.0
TRIM41	2419.0
SPSB1	2416.0
MICB	2384.0
MS4A3	2372.0
MYC	2367.0
ICAM4	2330.0
MLEC	2315.0
TNFSF14	2299.0
BTBD1	2261.0
PTPRC	2253.0
RBCK1	2239.0
MADCAM1	2192.0
OPRM1	2186.0
CST3	2157.0
RASA1	2134.0
SVIP	2123.0
BTN1A1	2115.0
ATF2	2110.0
SLC2A5	2109.0
UBE2O	2107.0
ARRB1	2098.0
HSP90B1	2086.0
TRIM4	2051.0
TRIM9	2050.0
PSMC3	2018.0
CFD	2016.0
UBE4A	1987.0
GSDMD	1976.0
UBE2N	1951.0
EREG	1906.0
UBE3B	1900.0
CAMK2G	1888.0
HGSNAT	1871.0
NANOG	1867.0
NME2	1853.0
GBP6	1836.0
SCAMP1	1834.0
IRS1	1806.0
CXCL8	1797.0
UBE2E2	1781.0
FLNB	1750.0
AP1M2	1740.0
PPL	1733.0
MAP2K7	1647.0
PSMD10	1646.0
PIK3C3	1626.0
POU2F1	1611.0
SUGT1	1576.0
ASB9	1560.0
FCGR2B	1525.0
ATG5	1445.0
NOS1	1401.0
ITCH	1394.0
HSP90AA1	1348.0
ASB3	1343.0
KPNA1	1320.0
BRAF	1314.0
AGER	1309.0
VRK3	1293.0
KLHL9	1277.0
NPDC1	1276.0
IL18RAP	1270.0
NHLRC3	1267.0
HECTD3	1254.0
ZBTB16	1252.0
BOLA2	1240.0
SEC31A	1144.0
UBA52	1071.0
APEH	1061.0
RIPK2	1042.0
ELK1	1040.0
HLA-C	1032.0
FBXL3	1026.0
HERC3	1024.0
IFI27	1014.0
DHX9	984.0
KPNA3	958.0
KIF11	950.0
NFASC	884.0
CUL5	847.0
KIF2C	812.0
NUP62	772.0
CENPE	741.0
ZNRF2	714.0
IGHV1-2	679.0
HLA-B	658.0
ATP7A	647.0
STX4	626.0
TNFRSF9	594.0
WIPF1	581.0
TXNDC5	548.0
FLNA	547.0
RAB44	540.0
TRIM6	526.0
TMEM179B	497.0
CSF1R	487.0
PYGB	484.0
LRMP	447.0
ADGRE3	396.0
IL33	392.0
NKIRAS1	387.0
AKT2	345.0
NCKIPSD	320.0
MLST8	304.0
EEF2	289.0
WASL	283.0
FGL2	275.0
FBXW5	244.0
ABL1	229.0
GSTP1	197.0
IL17RC	185.0
IGHV2-5	174.0
IGHV3-53	122.0
RASAL2	112.0
FRK	94.0
IFI16	46.0
RAPGEF3	25.0
KCNAB2	0.0
KLHL13	-4.0
IGLC3	-37.0
ABHD17B	-38.0
PTPN3	-46.0
ITGB1	-50.0
CD86	-71.0
PRDX4	-86.0
NFKBIB	-88.0
MRC2	-90.0
IGKV1-39	-173.0
BAIAP2	-179.0
HMGB1	-200.0
TRAF6	-241.0
PPP2R1B	-246.0
IFITM3	-308.0
MEF2C	-319.0
IGKV5-2	-357.0
IGLV5-45	-419.0
IGHV3-7	-437.0
IGKV3-11	-446.0
GHR	-458.0
ERBB3	-468.0
CASP3	-499.0
PSMA4	-538.0
EDA	-551.0
IGHV3-48	-583.0
PPP2R5E	-627.0
CHI3L1	-634.0
ARL2	-643.0
TLR7	-655.0
CDC27	-659.0
FBXO41	-664.0
RAP2B	-691.0
TNFSF15	-703.0
DIAPH1	-704.0
IGLV2-8	-740.0
CD180	-761.0
PIANP	-762.0
ICMT	-766.0
RASAL1	-777.0
ATG12	-784.0
RANBP2	-808.0
IGHV1-46	-823.0
NFKB2	-865.0
MAPK12	-946.0
PSMC5	-948.0
UBOX5	-959.0
IGKV1-5	-984.0
IGKV1-16	-990.0
IGHV3-23	-1042.0
RPLP0	-1054.0
KIF2A	-1080.0
STUB1	-1093.0
ULBP3	-1097.0
PTPN22	-1112.0
FBXO15	-1131.0
RBBP6	-1139.0
LCP2	-1167.0
IGKV1D-39	-1172.0
PTPN23	-1197.0
TREX1	-1227.0
DSP	-1230.0
TRIM3	-1254.0
CRLF1	-1280.0
IGKV2D-28	-1291.0
MAPK7	-1294.0
FBXL12	-1327.0
IGLV7-46	-1341.0
CREB1	-1382.0
GAN	-1402.0
IGLV10-54	-1414.0
IGHV3-13	-1436.0
COMMD3	-1441.0
IGLV2-18	-1472.0
TNFRSF13B	-1496.0
DUSP10	-1587.0
IGKV1-33	-1613.0
IGLV1-36	-1670.0
AIM2	-1685.0
OSMR	-1693.0
NOS3	-1718.0
IGKV2-30	-1725.0
IGLV4-69	-1768.0
POLR2K	-1792.0
RELA	-1807.0
IGHV1-69	-1811.0
TXLNA	-1837.0
CD200	-1863.0
NRG4	-1939.0
ABHD17C	-1955.0
IGHV4-59	-1969.0
LRRC7	-2007.0
IGLV3-19	-2016.0
CSF1	-2030.0
IGKV3-15	-2034.0
ILF2	-2037.0
IGHV3-11	-2041.0
CALM1	-2048.0
VTN	-2057.0
CD300A	-2076.0
IGHV4-34	-2080.0
EDA2R	-2084.0
UBR4	-2107.0
IGHM	-2111.0
UNKL	-2197.0
ASB14	-2209.0
IGHV3-30	-2221.0
ATP6V1C2	-2222.0
FZR1	-2253.0
MUCL1	-2297.0
PGLYRP2	-2301.0
ARIH1	-2309.0
FBXO6	-2328.0
AP1S2	-2330.0
C1S	-2334.0
HLA-G	-2370.0
PTPN14	-2421.0
CASP2	-2478.0
ADGRE5	-2501.0
HECTD1	-2504.0
POLR3K	-2543.0
CD1A	-2557.0
LTN1	-2562.0
HLA-A	-2578.0
SOCS2	-2581.0
SMURF1	-2584.0
ORM2	-2594.0
IGLV2-23	-2597.0
SEC24C	-2615.0
MUC4	-2624.0
IGKV4-1	-2625.0
C4BPB	-2678.0
KIF18A	-2744.0
AP2B1	-2748.0
ENAH	-2766.0
APRT	-2769.0
ASB6	-2780.0
IGLV2-11	-2782.0
IGKV1-17	-2799.0
CTSV	-2816.0
POLR2H	-2817.0
IGKV3-20	-2824.0
IGLV6-57	-2876.0
FGFR4	-2892.0
TLR10	-2899.0
IGHV3-33	-2989.0
SIAH1	-3004.0
MUC6	-3012.0
LAMA5	-3030.0
PHB	-3050.0
IGLV1-44	-3076.0
NUP85	-3077.0
PSMB8	-3080.0
CCL3	-3120.0
AGL	-3177.0
IGHV2-70	-3195.0
KIF15	-3246.0
DUSP7	-3253.0
PIN1	-3272.0
PFKL	-3284.0
MUC16	-3285.0
PDCD1LG2	-3315.0
HRAS	-3335.0
ALDOC	-3343.0
HTN1	-3350.0
KSR2	-3364.0
CUL7	-3371.0
IGHG3	-3394.0
MME	-3410.0
CPNE1	-3422.0
FRS2	-3430.0
TNFSF11	-3438.0
SPTBN5	-3449.0
CASP10	-3491.0
ADAR	-3508.0
PTPN20	-3554.0
CFB	-3571.0
KBTBD6	-3608.0
AIP	-3644.0
FCER2	-3678.0
AAMP	-3695.0
TRIM11	-3724.0
IGHV4-39	-3735.0
FBXO22	-3743.0
CD19	-3769.0
DAB2IP	-3780.0
STK10	-3811.0
MIF	-3828.0
CR2	-3883.0
HLA-H	-3892.0
SLC27A2	-3903.0
TNFRSF17	-3943.0
PAQR3	-3952.0
PA2G4	-3965.0
INPP5D	-3984.0
FGF7	-3999.0
MYLIP	-4005.0
IGKV3D-20	-4012.0
PIK3R4	-4040.0
DYNLL2	-4042.0
STX1A	-4061.0
VAV2	-4073.0
IGLV3-1	-4093.0
SPSB2	-4099.0
IGLV7-43	-4100.0
IGLV1-40	-4105.0
DCTN5	-4140.0
IGHD	-4143.0
COLEC12	-4188.0
PAK3	-4194.0
IGKC	-4212.0
KBTBD8	-4233.0
IGLV3-25	-4239.0
TNFRSF13C	-4326.0
RASA2	-4348.0
CD22	-4379.0
AGA	-4398.0
IGLV1-51	-4413.0
HLA-E	-4448.0
IGLV3-21	-4455.0
TRIM2	-4468.0
XRCC6	-4475.0
BCL2	-4480.0
CNKSR2	-4481.0
OPRD1	-4494.0
PTPRA	-4528.0
HLA-DOB	-4538.0
DPP7	-4544.0
KIF26A	-4564.0
RBSN	-4574.0
EPX	-4583.0
MUC5B	-4618.0
LEAP2	-4665.0
RCE1	-4695.0
SYNGR1	-4703.0
LGMN	-4724.0
PIGR	-4739.0
IGLC7	-4779.0
HLA-DQA2	-4793.0
UBR1	-4802.0
LNX1	-4847.0
CD40	-4853.0
SOD1	-4927.0
BTRC	-4932.0
KIR2DL4	-4968.0
BTLA	-5020.0
CD79A	-5023.0
S100B	-5025.0
EEF1A1	-5073.0
ANAPC10	-5074.0
SH3RF1	-5092.0
FBXO27	-5112.0
OTUD5	-5121.0
HLA-DRB5	-5140.0
MASP2	-5154.0
IGHE	-5174.0
BTNL9	-5176.0
SPTBN2	-5189.0
MICA	-5216.0
IGKV1-12	-5223.0
HCST	-5228.0
POLR3F	-5248.0
DHX36	-5253.0
ANAPC7	-5259.0
BTBD6	-5265.0
ERAP2	-5268.0
IL17RE	-5274.0
IKBKB	-5290.0
TRAF3	-5296.0
NFKBIE	-5304.0
IL15	-5313.0
PSMA3	-5314.0
CD4	-5320.0
FGFR1	-5335.0
IGLC2	-5370.0
CLEC10A	-5371.0
BLK	-5390.0
IGLV8-61	-5395.0
POLR3G	-5426.0
DTX3L	-5531.0
JUP	-5541.0
IGLC1	-5548.0
AP1S3	-5592.0
DLG2	-5599.0
NUP42	-5622.0
NEFL	-5629.0
RASGEF1A	-5631.0
IGHG1	-5669.0
ASB4	-5677.0
FNTA	-5702.0
HLA-DQB1	-5703.0
SOS1	-5714.0
CFH	-5728.0
PSMB10	-5768.0
MTAP	-5771.0
IGKV2-28	-5778.0
MUC20	-5791.0
IFI35	-5797.0
IGLV1-47	-5810.0
OSBPL1A	-5827.0
MRAS	-5840.0
HACE1	-5874.0
MX2	-5891.0
TRIB3	-5896.0
TLR9	-5909.0
IGLV3-27	-5935.0
SEH1L	-5957.0
NLRP1	-5972.0
CDC16	-6037.0
FBXL14	-6062.0
PSME4	-6099.0
KLHL11	-6134.0
PSMA5	-6154.0
RNF34	-6162.0
IFITM1	-6178.0
ICOSLG	-6183.0
TNFSF9	-6222.0
ITLN1	-6277.0
NUP153	-6325.0
PDZD11	-6343.0
EDAR	-6367.0
RNF220	-6371.0
PDE12	-6380.0
CD70	-6403.0
TNFRSF4	-6409.0
FBXO10	-6411.0
DUSP4	-6432.0
TNFRSF14	-6437.0
RAB9B	-6471.0
PLPP5	-6508.0
CAND1	-6550.0
RET	-6557.0
DSC1	-6597.0
NF2	-6614.0
IL17RB	-6628.0
DUSP16	-6652.0
IL17C	-6676.0
HSP90AB1	-6702.0
FBXW7	-6709.0
FBXL16	-6710.0
IGHG4	-6718.0
ASB16	-6721.0
TRIM36	-6733.0
RASGRF1	-6738.0
TRIM14	-6763.0
ANAPC4	-6780.0
UFL1	-6788.0
PTGES2	-6796.0
CD274	-6803.0
CD80	-6837.0
SIGLEC8	-6838.0
FGF23	-6840.0
KPNA2	-6845.0
CCND1	-6847.0
CNKSR1	-6858.0
RPS27A	-6894.0
PPIA	-6900.0
PEA15	-6947.0
SIKE1	-6959.0
PDCD1	-6963.0
SPRED3	-6979.0
BLNK	-6993.0
B2M	-7019.0
ZEB1	-7029.0
TRAT1	-7043.0
TUBB	-7078.0
CCR6	-7086.0
IGHG2	-7087.0
TPR	-7100.0
TRIM5	-7102.0
MT2A	-7168.0
MAPK9	-7182.0
GBP2	-7189.0
ORAI1	-7202.0
CD79B	-7218.0
HRNR	-7225.0
ERAP1	-7234.0
TNF	-7241.0
TNFSF8	-7251.0
ANAPC2	-7284.0
IL2RA	-7301.0
POM121C	-7305.0
POLR3A	-7359.0
RNF25	-7377.0
IL12A	-7399.0
FBXW9	-7412.0
SPTBN1	-7419.0
UBA7	-7455.0
IGLV3-12	-7472.0
POLR3B	-7484.0
LTB	-7494.0
BST2	-7533.0
POLR3C	-7545.0
ITPR1	-7553.0
LPCAT1	-7557.0
PSMA8	-7559.0
PPP5C	-7588.0
CD8B	-7599.0
POLR3GL	-7616.0
TRIM46	-7639.0
PTPRB	-7737.0
LRR1	-7760.0
TRIM45	-7771.0
TNFRSF11A	-7808.0
DYNC1H1	-7822.0
TNFRSF18	-7833.0
NUP133	-7839.0
TRIM37	-7861.0
IL31RA	-7869.0
UBE2G2	-7879.0
MRE11	-7888.0
PRKCE	-8024.0
HUWE1	-8044.0
LAIR2	-8050.0
RASGRP2	-8137.0
HLA-DRB1	-8159.0
FBXO2	-8199.0
UBA5	-8208.0
KLC4	-8231.0
GBP3	-8248.0
POM121	-8263.0
S100A1	-8267.0
CD226	-8269.0
RORC	-8272.0
BTN2A1	-8287.0
KIF5C	-8297.0
SKP2	-8307.0
AAAS	-8337.0
DLG1	-8338.0
SH2B1	-8341.0
KIF5A	-8378.0
KIR2DS4	-8380.0
IGLV2-14	-8416.0
TMEM63A	-8437.0
KLHL42	-8445.0
FBXW12	-8474.0
IRF3	-8479.0
NUP54	-8521.0
CDK13	-8535.0
PRKG2	-8538.0
IRF1	-8550.0
PDGFB	-8575.0
IL7	-8618.0
SPRED1	-8664.0
IFNLR1	-8686.0
KLC2	-8724.0
CCT2	-8727.0
FGF22	-8733.0
SYNGAP1	-8744.0
TPP2	-8756.0
PPIE	-8762.0
KIFAP3	-8777.0
GFRA2	-8804.0
ICOS	-8862.0
FGF9	-8873.0
HECTD2	-8878.0
PML	-8888.0
IRF7	-8889.0
TRIM56	-8899.0
CD200R1	-8912.0
RASGRP3	-8923.0
KIR2DL3	-8925.0
IRF4	-8965.0
CCR5	-8977.0
SRC	-9011.0
CIITA	-9026.0
CYLD	-9037.0
DET1	-9075.0
CLEC2B	-9076.0
IL20RB	-9098.0
CD34	-9102.0
LTA	-9108.0
FOXO1	-9173.0
CRACR2A	-9184.0
BRWD1	-9192.0
CD209	-9237.0
S1PR1	-9239.0
FBXO44	-9242.0
TRIM26	-9245.0
IL16	-9259.0
HLA-DMB	-9267.0
ATP6V1G2	-9275.0
PSMC4	-9306.0
NFATC1	-9315.0
SIGLEC6	-9316.0
FBXL22	-9326.0
TRAV29DV5	-9334.0
THOP1	-9344.0
CEP290	-9354.0
HERC1	-9355.0
LMO7	-9377.0
TRAV8-4	-9384.0
HLA-DQB2	-9390.0
EIF2AK2	-9395.0
FLT3LG	-9400.0
CD81	-9413.0
TRPC1	-9415.0
CD40LG	-9426.0
IL11RA	-9436.0
CCNF	-9479.0
CD27	-9483.0
RASGRF2	-9554.0
TRBV7-9	-9564.0
PJA1	-9565.0
DUSP2	-9580.0
RICTOR	-9593.0
NUP43	-9595.0
IMPDH2	-9608.0
MAPK8	-9646.0
IRAK2	-9718.0
PIK3R1	-9725.0
TNFRSF25	-9734.0
IL32	-9735.0
IRF6	-9748.0
RNF115	-9751.0
GBP1	-9769.0
KLRC2	-9779.0
OAS1	-9790.0
TXNIP	-9792.0
ENPP4	-9810.0
TRIM69	-9817.0
IL23A	-9830.0
LNPEP	-9853.0
CD28	-9858.0
HLA-DMA	-9894.0
TRIM35	-9906.0
C1R	-9909.0
ATAD3B	-9936.0
MTOR	-9948.0
ITPR3	-9955.0
HSPA9	-9981.0
ORMDL3	-9994.0
FBXW8	-10006.0
TRAV19	-10023.0
RAPGEF1	-10033.0
WWP1	-10036.0
PSME1	-10138.0
SNRPA1	-10141.0
PTPN13	-10143.0
NLRC5	-10156.0
IL4	-10166.0
CRTAM	-10168.0
PRKDC	-10173.0
NUP35	-10206.0
SMURF2	-10250.0
IP6K2	-10258.0
POLR3H	-10263.0
TRBV12-3	-10279.0
NUP155	-10291.0
IFNG	-10320.0
IL7R	-10324.0
TRIM17	-10341.0
TMC6	-10352.0
RNF216	-10357.0
KLHL25	-10363.0
ACTR1B	-10368.0
RNF19A	-10380.0
NUP160	-10383.0
CYFIP2	-10387.0
POLR1C	-10390.0
PSME2	-10415.0
CD8A	-10449.0
TRIM39	-10450.0
ALOX15	-10452.0
PLCG1	-10473.0
LAG3	-10498.0
CTLA4	-10563.0
PRLR	-10565.0
NUP107	-10570.0
ABCE1	-10608.0
SIGIRR	-10688.0
MALT1	-10701.0
RNF126	-10705.0
NUP210	-10725.0
TAP1	-10727.0
IL18BP	-10728.0
HERC2	-10745.0
IL10RA	-10759.0
HLA-F	-10771.0
ABHD17A	-10780.0
KIR2DL1	-10787.0
FBXO32	-10797.0
TRIM62	-10798.0
DZIP3	-10816.0
BIRC3	-10830.0
FBXO21	-10844.0
UBE3D	-10854.0
IL24	-10868.0
SEC61A2	-10873.0
MUC12	-10883.0
STAT2	-10885.0
ABI2	-10893.0
EIF4A2	-10909.0
HSPA8	-10913.0
TP53	-10936.0
DSN1	-10945.0
TRAC	-10981.0
THEM4	-10987.0
KCTD7	-10994.0
ITGA4	-11003.0
ITGAL	-11015.0
KLRC1	-11018.0
PTPN7	-11022.0
EDARADD	-11029.0
KIT	-11031.0
CD3E	-11042.0
MIB2	-11044.0
NUP88	-11046.0
KLHL22	-11058.0
OASL	-11059.0
CLCF1	-11060.0
ITK	-11066.0
TRIM22	-11072.0
JAK1	-11075.0
POLR3E	-11083.0
UBE2Z	-11084.0
GBP5	-11091.0
CD3D	-11094.0
ANAPC5	-11108.0
NCR3	-11114.0
PILRB	-11115.0
TNFAIP3	-11131.0
CCL5	-11152.0
KIR3DL1	-11153.0
MS4A2	-11156.0
RIPK1	-11184.0
RASA4	-11187.0
GLMN	-11202.0
HNRNPDL	-11221.0
KLHL3	-11236.0
IRF9	-11237.0
IL5RA	-11247.0
NUP205	-11250.0
PEBP1	-11270.0
KLRG1	-11271.0
RNF125	-11320.0
PDE3B	-11323.0
CDC23	-11349.0
UBE2D4	-11360.0
PSMB9	-11362.0
TRIM32	-11375.0
LAT	-11376.0
CD3G	-11409.0
PPP2R5C	-11413.0
UBE2L6	-11415.0
IFIT5	-11430.0
SPTAN1	-11438.0
KIR3DL2	-11441.0
SERPING1	-11444.0
FRMPD3	-11446.0
PDGFRB	-11452.0
CASP8	-11463.0
CUL1	-11467.0
TRAIP	-11468.0
ATP6V0E2	-11475.0
MAP3K14	-11478.0
CTSF	-11482.0
NCK1	-11488.0
LCK	-11492.0
CTSO	-11494.0
CD74	-11498.0
IFIH1	-11499.0
KLHL20	-11500.0
GNLY	-11505.0
CDH1	-11512.0
RAG1	-11517.0
HLA-DOA	-11536.0
TLR3	-11538.0
SMAD3	-11541.0
NUP188	-11545.0
POLR3D	-11556.0
TBC1D10C	-11564.0
RNF4	-11568.0
BTN2A2	-11576.0
FBXW4	-11593.0
TRAF2	-11594.0
DUSP8	-11604.0
RPS6KA5	-11616.0
UBE2Q2	-11642.0
FCGR3A	-11661.0
NIT2	-11684.0
VAMP2	-11692.0
C8G	-11697.0
NUP93	-11700.0
ISG20	-11710.0
BTN3A2	-11723.0
CAMK2D	-11728.0
NCAM1	-11736.0
RASA3	-11752.0
FGFR2	-11753.0
FYN	-11758.0
TXK	-11762.0
HLA-DQA1	-11763.0
STAT1	-11769.0
PDCD4	-11779.0
ATP8A1	-11780.0
HMOX2	-11783.0
AKT3	-11804.0
CD160	-11811.0
RAB37	-11814.0
GZMM	-11815.0
RASGRP1	-11817.0
TAP2	-11828.0
ZAP70	-11833.0
GBP4	-11846.0
DLG3	-11848.0
PRKACB	-11857.0
TRBC1	-11859.0
KPNA5	-11861.0
CLEC4C	-11862.0
NCR3LG1	-11865.0
FBXO4	-11867.0
ANAPC1	-11870.0
RORA	-11872.0
RASAL3	-11874.0
DHX58	-11880.0
FBXO31	-11894.0
RNF213	-11921.0
FCER1A	-11937.0
PRR5	-11948.0
IFI6	-11953.0
KIF3A	-11957.0
TRIM68	-11964.0
SARM1	-11973.0
DDX58	-11974.0
IL2RG	-11983.0
CD96	-11992.0
ICAM2	-11994.0
HLA-DRA	-12007.0
CCL4	-12010.0
ASB2	-12015.0
PLA2G6	-12020.0
IL12RB2	-12025.0
CARD11	-12035.0
PIK3R3	-12037.0
PRKCQ	-12039.0
EVL	-12046.0
ITGB7	-12054.0
NLRC3	-12056.0
IL3RA	-12063.0
CD1C	-12064.0
ARIH2	-12087.0
KLRD1	-12088.0
LILRA4	-12094.0
ISG15	-12099.0
IL12RB1	-12101.0
IL9R	-12104.0
MEX3C	-12106.0
CD47	-12112.0
NDC1	-12113.0
RALGDS	-12117.0
CLEC2D	-12120.0
IFIT3	-12122.0
XAF1	-12125.0
SH2D1A	-12126.0
SLAMF7	-12130.0
PTPN4	-12133.0
RSAD2	-12138.0
NFATC3	-12139.0
GATA3	-12140.0
YES1	-12143.0
SLAMF6	-12151.0
OAS2	-12153.0
IFIT2	-12156.0
MX1	-12166.0
IL21R	-12176.0
ATP6V0A2	-12193.0
HERC6	-12199.0
DUSP5	-12201.0
HLA-DPB1	-12203.0
SIGLEC1	-12205.0
USP18	-12221.0
KLRK1	-12224.0
HERC5	-12225.0
KLRB1	-12228.0
OAS3	-12229.0
NOD1	-12234.0
NFATC2	-12236.0
BTN3A3	-12237.0
C3	-12243.0
STAT4	-12265.0
CBLB	-12266.0
HLA-DPA1	-12271.0
ZBP1	-12280.0
ERBB2	-12281.0
CXCL10	-12284.0
KIF22	-12286.0
RHOF	-12291.0
CD247	-12295.0
IFIT1	-12296.0
CCL2	-12298.0
KLRF1	-12299.0
PLD4	-12302.0
BTN3A1	-12304.0
IL2RB	-12307.0
SH2D1B	-12318.0
FASLG	-12319.0
NCR1	-12321.0

---

Membrane Trafficking

	631
set	Membrane Trafficking
setSize	559
pANOVA	7.39e-36
s.dist	0.309
p.adjustANOVA	2.52e-33

Top enriched genes

GeneID	Gene Rank
VAMP7	9549
F5	9524
RAB32	9504
PLIN3	9485
RAB13	9443
TBC1D2	9355
RAB31	9353
AP1S1	9338
GRB2	9320
YWHAG	9310
GNS	9309
AGFG1	9261
SPTB	9250
PLA2G4A	9234
SORT1	9208
ARF4	9201
ITSN1	9186
SERPINA1	9179
KDELR1	9163
DCTN2	9158

Click HERE to show all gene set members

GeneID	Gene Rank
VAMP7	9549
F5	9524
RAB32	9504
PLIN3	9485
RAB13	9443
TBC1D2	9355
RAB31	9353
AP1S1	9338
GRB2	9320
YWHAG	9310
GNS	9309
AGFG1	9261
SPTB	9250
PLA2G4A	9234
SORT1	9208
ARF4	9201
ITSN1	9186
SERPINA1	9179
KDELR1	9163
DCTN2	9158
CD55	9157
RAB3IL1	9153
GABARAPL2	9150
APP	9123
ARF1	9083
RAB1A	9075
CLTC	9056
PICALM	9052
STX10	9047
SBF2	9037
TGFA	9031
YWHAE	9009
CTSZ	9001
TBC1D14	8995
CLTCL1	8939
ARPC1A	8923
RAB10	8915
CUX1	8905
CPD	8901
ANK1	8897
GALNT2	8896
RALGAPA2	8890
AMPH	8875
CHMP2A	8863
EXOC6	8851
CHMP4B	8830
NSF	8815
BICD2	8786
UBAP1	8779
RAB7A	8775
AP1B1	8741
BLOC1S1	8726
RAC1	8720
RAB11A	8715
FTL	8698
RAB5C	8688
AP2M1	8673
FNBP1L	8672
ARPC5	8653
TGOLN2	8647
YWHAH	8621
SNAP23	8578
CAPZA2	8521
ARRB2	8517
RAB27A	8504
KIF3C	8451
HIP1	8445
RAB1B	8407
CLTA	8402
DCTN4	8385
AP3B1	8377
CHMP3	8339
COPA	8319
ARPC3	8309
KIF1B	8290
REPS2	8273
EGF	8267
DAB2	8259
RAB3A	8247
RIN2	8238
RAB6A	8223
PACSIN2	8208
CAPZA1	8165
TBC1D10B	8158
KIF5B	8144
SEC24D	8130
VAMP3	8121
MAP1LC3B	8099
TOR1A	8085
AP2S1	8080
CAPZB	8057
GJD3	8052
RAB4A	8050
EPN1	8026
DENND3	7981
MAN1A1	7979
ARF5	7975
VPS37C	7973
GABARAP	7967
COPB2	7965
TMED7	7909
STX6	7907
RAB18	7893
ACTR3	7888
TRAPPC1	7887
AP3S1	7876
TSG101	7856
CNIH1	7832
ACTR2	7827
SNX2	7821
KIF1C	7816
ARF3	7798
SPTA1	7785
FCHO2	7762
DENND5A	7737
SH3GL1	7733
SEC24A	7716
VPS25	7696
ACTR10	7652
COPG2	7636
DYNC1I2	7629
ARPC4	7605
CBL	7599
KDELR2	7585
RIN1	7572
RABGEF1	7569
VPS54	7564
NAA38	7561
SNAPIN	7535
COPG1	7533
RHOQ	7504
KLC3	7479
ARPC2	7449
STXBP3	7442
MVB12A	7425
SEC23A	7416
DENND1A	7406
COPB1	7399
RAB33B	7385
DCTN6	7382
AP2A2	7360
GDI2	7337
IGF2R	7270
TFG	7240
TMED9	7199
STX5	7186
LMAN2	7178
DNM3	7167
RAB5A	7166
TRAPPC3	7158
SURF4	7147
ULK1	7143
MCFD2	7136
TBC1D1	7120
SNX18	7107
RAB14	7090
ACTR1A	7088
RAB39A	7059
PAFAH1B2	7026
LMAN2L	7003
F8	6996
DYNC1LI1	6992
COPE	6979
PPP6C	6887
GAPVD1	6866
DNASE2	6841
TRAPPC8	6827
BLOC1S6	6811
RAB5B	6801
AP1M1	6788
MYH9	6772
UBB	6737
RIC1	6733
MON1B	6714
MYO5A	6685
GORASP1	6670
MAN2A2	6669
COPS7A	6649
AP2A1	6628
RAB8B	6617
NEDD8	6597
SAR1B	6562
TBC1D7	6561
VPS37A	6560
GALNT1	6518
RAB43	6507
GRK3	6469
PREB	6450
OCRL	6436
AP4E1	6424
SNAP29	6418
YWHAB	6398
TRAPPC12	6394
COL7A1	6375
LDLR	6329
SYNJ1	6310
RAB21	6237
VTA1	6232
SH3KBP1	6227
GOLGA2	6217
CLTB	6195
STAM2	6183
CYTH4	6170
DNM2	6163
RAB6B	6149
COPS2	6147
GRK2	6141
TMED2	6098
DCTN3	6080
DENND2C	6056
DYNLL1	6049
KIF13B	6047
COPS3	6040
UBQLN2	6009
CTTN	5999
SNF8	5990
CD59	5964
SEC22B	5939
YIPF6	5924
ACBD3	5898
SEC13	5820
GDI1	5807
RAB3GAP1	5800
RAB36	5722
CHMP2B	5713
EXOC1	5710
YWHAZ	5687
HPS1	5679
EXOC4	5662
ARCN1	5661
MIA2	5618
TMEM115	5605
KLC1	5596
CHMP6	5590
KIF23	5584
PRKAG1	5582
PAFAH1B1	5534
AREG	5494
TRAPPC9	5414
VTI1A	5381
GOLGA5	5333
PPP6R1	5328
VAMP8	5284
VPS4B	5279
YKT6	5277
TRAPPC11	5269
TRAPPC5	5253
MVB12B	5251
KIF20A	5165
UBQLN1	5164
SYT1	5162
DCTN1	5143
GOLIM4	5122
ITSN2	5108
EXOC7	4998
SCARB2	4979
CHMP5	4954
HBEGF	4878
FTH1	4867
GJB6	4826
EXOC3	4767
DNAJC6	4706
SEC16A	4687
STX18	4684
AGPAT3	4625
RGP1	4599
HGS	4570
RABEPK	4493
USP6NL	4486
RAB3GAP2	4478
RAB11B	4445
UBC	4421
COPS5	4415
PAFAH1B3	4373
COG7	4321
CCZ1	4314
KIF9	4310
DYNC1LI2	4253
VPS28	4247
DYNC1I1	4211
TRAPPC6B	4201
USO1	4192
NAPG	4190
EPS15	4189
EXOC5	4181
RAB9A	4177
COPZ1	4081
AP1G1	4052
RAB35	4030
VPS37B	3933
CLINT1	3903
RAB8A	3874
GGA3	3846
TBC1D13	3828
ARFGAP3	3807
KIF3B	3773
STX16	3771
KIF4A	3763
STON2	3698
EPS15L1	3688
TBC1D15	3678
AKT1	3656
SEC24B	3655
SCFD1	3593
RAB27B	3588
DNM1	3526
PIP5K1C	3436
NECAP2	3428
TBC1D16	3385
KIAA0319	3373
MYO1C	3351
PUM1	3325
PPP6R3	3323
RAB3IP	3276
TBC1D24	3254
VAMP4	3236
ALS2	3234
DENND4B	3189
DENND6B	3049
RACGAP1	2921
KIF16B	2817
TMED3	2779
GCC1	2756
CFTR	2738
RALA	2686
STON1	2624
GAK	2606
EPGN	2579
KIF27	2576
CTSC	2547
VPS45	2526
TMF1	2524
CHMP4A	2480
GOLGA1	2474
CSNK1D	2412
GGA1	2327
CHM	2291
TRIP10	2267
NECAP1	2247
ARRB1	2098
RABGAP1	2085
PRKAG2	1942
EREG	1906
COPS4	1865
AP1M2	1740
COPS6	1663
TFRC	1578
SFN	1557
ARF6	1407
TBC1D8B	1399
NAPA	1385
PRKAB1	1302
STAM	1299
LRP2	1222
TF	1172
KIF6	1162
DTNBP1	1153
SEC31A	1144
UBA52	1071
CCZ1B	1066
KIF11	950
USE1	922
KIF2C	812
VPS4A	776
CENPE	741
CNIH2	727
GJC2	662
STX4	626
TXNDC5	548
GJC1	538
CYTH2	456
SYT2	451
SEC16B	351
AKT2	345
SYS1	330
TMED10	328
AVPR2	306
WASL	283
ANKRD27	281
AP4M1	234
NBAS	195
TBC1D3	73
ZW10	37
COG4	15
EXOC8	-23
TBC1D20	-49
KIF18B	-123
VPS53	-130
GOSR1	-160
KIFC1	-166
FNBP1	-320
SNX9	-404
DENND6A	-405
COG8	-406
SEC23IP	-469
TRIP11	-591
BET1	-631
TSC2	-804
RAB12	-874
SCOC	-894
KIF2A	-1080
CHML	-1348
MAN2A1	-1350
GOSR2	-1504
RAB7B	-1528
KIFC2	-1555
TOR1B	-1930
ARFGAP1	-1962
MAN1A2	-2017
FCHO1	-2036
CALM1	-2048
TSC1	-2097
KDELR3	-2154
AP1S2	-2330
TRAPPC2L	-2337
TRAPPC13	-2510
SEC24C	-2615
KIF18A	-2744
AP2B1	-2748
NAPB	-2763
MON1A	-3035
ARFIP2	-3098
SNX5	-3179
TPD52L1	-3229
KIF15	-3246
COG5	-3318
SPTBN5	-3449
VPS52	-3628
RAB41	-3915
EPN2	-3979
DENND5B	-4020
DYNLL2	-4042
GOLGA4	-4063
SH3D19	-4106
DCTN5	-4140
RALGAPB	-4157
SEC22C	-4285
GBF1	-4322
GJA3	-4488
KIF26A	-4564
GPS1	-4577
ANK3	-4974
SEC22A	-5080
ARL1	-5130
ASPSCR1	-5158
SPTBN2	-5189
COG3	-5230
PIK3C2A	-5233
CD4	-5320
AP1G2	-5381
GOLGB1	-5425
DENND4A	-5472
AP1S3	-5592
AP4S1	-5732
ARFGAP2	-5850
COG6	-5872
ANKRD28	-6311
MIA3	-6330
MAN1C1	-6459
TJP1	-6461
RAB9B	-6471
GGA2	-6523
VPS51	-6565
SYT11	-6617
KIF28P	-6736
KIF21B	-6771
TRAPPC4	-6836
RPS27A	-6894
VPS36	-6942
REPS1	-7232
DENND1C	-7293
BICD1	-7322
AP4B1	-7350
BET1L	-7385
BLOC1S4	-7403
SPTBN1	-7419
YWHAQ	-7471
ARFRP1	-7488
TBC1D25	-7519
BNIP1	-7543
DENND4C	-7590
C2CD5	-7696
ALS2CL	-7707
GCC2	-7725
EXOC2	-7746
DYNC1H1	-7822
KIF20B	-7903
COG2	-8023
PRKAB2	-8083
KLC4	-8231
KIF5C	-8297
CHMP7	-8325
CYTH3	-8377
KIF5A	-8378
DENND2A	-8504
SYNJ2	-8530
M6PR	-8665
TBC1D17	-8705
KLC2	-8724
KIFAP3	-8777
BLOC1S3	-8808
RAB38	-8811
TRAPPC2	-8851
COPS8	-8868
LDLRAP1	-8898
RAB30	-8959
SRC	-9011
CNIH3	-9196
AAK1	-9323
TPD52	-9423
DENND1B	-9482
TRAPPC10	-9516
NAA30	-9664
SYTL1	-9782
LNPEP	-9853
COPS7B	-9938
POLG	-9958
HIP1R	-10052
TBC1D4	-10161
RINT1	-10172
IL7R	-10324
RINL	-10520
SBF1	-10529
LMAN1	-10699
DVL2	-10753
HSPA8	-10913
TRAPPC6A	-10921
STX17	-11009
RAB33A	-11034
COPZ2	-11047
CD3D	-11094
BIN1	-11183
RHOBTB3	-11246
RAB39B	-11350
CD3G	-11409
SPTAN1	-11438
NAA35	-11460
HPS4	-11490
MYO6	-11522
TBC1D10C	-11564
KIF19	-11579
KIF26B	-11671
VAMP2	-11692
RABEP1	-11712
FZD4	-11733
OPTN	-11757
AKT3	-11804
SLC2A8	-11810
KIF21A	-11830
ADRB2	-11879
MADD	-11931
KIF3A	-11957
PLA2G6	-12020
TBC1D10A	-12038
COG1	-12057
DENND2D	-12158
CYTH1	-12174
KIF22	-12286
PACSIN1	-12327

---

Vesicle-mediated transport

	1312
set	Vesicle-mediated transport
setSize	650
pANOVA	3.62e-32
s.dist	0.271
p.adjustANOVA	9.87e-30

Top enriched genes

GeneID	Gene Rank
VAMP7	9549
STAB1	9543
F5	9524
HP	9518
RAB32	9504
CD163	9493
CD36	9486
PLIN3	9485
RAB13	9443
TBC1D2	9355
RAB31	9353
AP1S1	9338
GRB2	9320
YWHAG	9310
GNS	9309
AGFG1	9261
SPTB	9250
PLA2G4A	9234
SORT1	9208
ARF4	9201

Click HERE to show all gene set members

GeneID	Gene Rank
VAMP7	9549
STAB1	9543
F5	9524
HP	9518
RAB32	9504
CD163	9493
CD36	9486
PLIN3	9485
RAB13	9443
TBC1D2	9355
RAB31	9353
AP1S1	9338
GRB2	9320
YWHAG	9310
GNS	9309
AGFG1	9261
SPTB	9250
PLA2G4A	9234
SORT1	9208
ARF4	9201
ITSN1	9186
SERPINA1	9179
KDELR1	9163
DCTN2	9158
CD55	9157
RAB3IL1	9153
GABARAPL2	9150
APP	9123
HBA1	9095
ARF1	9083
LRP1	9081
RAB1A	9075
CLTC	9056
PICALM	9052
STX10	9047
SBF2	9037
TGFA	9031
YWHAE	9009
CTSZ	9001
TBC1D14	8995
CLTCL1	8939
ARPC1A	8923
RAB10	8915
CUX1	8905
CPD	8901
ANK1	8897
GALNT2	8896
RALGAPA2	8890
AMPH	8875
CHMP2A	8863
EXOC6	8851
CHMP4B	8830
NSF	8815
BICD2	8786
UBAP1	8779
RAB7A	8775
AP1B1	8741
BLOC1S1	8726
RAC1	8720
RAB11A	8715
FTL	8698
RAB5C	8688
AP2M1	8673
FNBP1L	8672
ARPC5	8653
TGOLN2	8647
YWHAH	8621
SNAP23	8578
HBB	8528
CAPZA2	8521
ARRB2	8517
RAB27A	8504
KIF3C	8451
HIP1	8445
RAB1B	8407
MARCO	8406
CLTA	8402
DCTN4	8385
AP3B1	8377
CHMP3	8339
COPA	8319
ARPC3	8309
KIF1B	8290
REPS2	8273
EGF	8267
DAB2	8259
RAB3A	8247
RIN2	8238
RAB6A	8223
PACSIN2	8208
CAPZA1	8165
TBC1D10B	8158
KIF5B	8144
SEC24D	8130
VAMP3	8121
MAP1LC3B	8099
TOR1A	8085
AP2S1	8080
CAPZB	8057
GJD3	8052
RAB4A	8050
EPN1	8026
DENND3	7981
MAN1A1	7979
ARF5	7975
VPS37C	7973
GABARAP	7967
COPB2	7965
TMED7	7909
STX6	7907
RAB18	7893
ACTR3	7888
TRAPPC1	7887
AP3S1	7876
TSG101	7856
CNIH1	7832
ACTR2	7827
SNX2	7821
KIF1C	7816
ARF3	7798
SPTA1	7785
FCHO2	7762
DENND5A	7737
SH3GL1	7733
SEC24A	7716
VPS25	7696
ACTR10	7652
COPG2	7636
DYNC1I2	7629
ARPC4	7605
CBL	7599
KDELR2	7585
RIN1	7572
RABGEF1	7569
VPS54	7564
NAA38	7561
SNAPIN	7535
COPG1	7533
RHOQ	7504
KLC3	7479
ARPC2	7449
STXBP3	7442
MVB12A	7425
SEC23A	7416
SPARC	7411
DENND1A	7406
COPB1	7399
RAB33B	7385
DCTN6	7382
AP2A2	7360
GDI2	7337
IGF2R	7270
TFG	7240
TMED9	7199
STX5	7186
LMAN2	7178
DNM3	7167
RAB5A	7166
TRAPPC3	7158
SURF4	7147
ULK1	7143
MCFD2	7136
TBC1D1	7120
SNX18	7107
RAB14	7090
ACTR1A	7088
RAB39A	7059
PAFAH1B2	7026
LMAN2L	7003
F8	6996
DYNC1LI1	6992
COPE	6979
PPP6C	6887
GAPVD1	6866
DNASE2	6841
TRAPPC8	6827
BLOC1S6	6811
RAB5B	6801
AP1M1	6788
MYH9	6772
UBB	6737
RIC1	6733
MON1B	6714
MYO5A	6685
GORASP1	6670
MAN2A2	6669
COPS7A	6649
AP2A1	6628
RAB8B	6617
NEDD8	6597
SAR1B	6562
TBC1D7	6561
VPS37A	6560
GALNT1	6518
RAB43	6507
GRK3	6469
PREB	6450
OCRL	6436
AP4E1	6424
SNAP29	6418
CALR	6415
YWHAB	6398
TRAPPC12	6394
COL7A1	6375
LDLR	6329
SYNJ1	6310
RAB21	6237
VTA1	6232
SH3KBP1	6227
GOLGA2	6217
CLTB	6195
STAM2	6183
CYTH4	6170
DNM2	6163
RAB6B	6149
COPS2	6147
GRK2	6141
TMED2	6098
DCTN3	6080
DENND2C	6056
DYNLL1	6049
KIF13B	6047
COPS3	6040
UBQLN2	6009
CTTN	5999
SNF8	5990
SCARB1	5987
CD59	5964
SEC22B	5939
YIPF6	5924
ACBD3	5898
SEC13	5820
GDI1	5807
RAB3GAP1	5800
RAB36	5722
CHMP2B	5713
EXOC1	5710
YWHAZ	5687
HPS1	5679
EXOC4	5662
ARCN1	5661
MIA2	5618
TMEM115	5605
STAB2	5599
KLC1	5596
CHMP6	5590
KIF23	5584
PRKAG1	5582
PAFAH1B1	5534
AREG	5494
TRAPPC9	5414
VTI1A	5381
GOLGA5	5333
PPP6R1	5328
VAMP8	5284
VPS4B	5279
YKT6	5277
TRAPPC11	5269
TRAPPC5	5253
MVB12B	5251
KIF20A	5165
UBQLN1	5164
SYT1	5162
DCTN1	5143
GOLIM4	5122
ITSN2	5108
EXOC7	4998
SCARB2	4979
CHMP5	4954
HBEGF	4878
FTH1	4867
GJB6	4826
EXOC3	4767
DNAJC6	4706
SEC16A	4687
STX18	4684
AGPAT3	4625
RGP1	4599
HGS	4570
RABEPK	4493
USP6NL	4486
RAB3GAP2	4478
RAB11B	4445
UBC	4421
COPS5	4415
PAFAH1B3	4373
COG7	4321
CCZ1	4314
KIF9	4310
DYNC1LI2	4253
VPS28	4247
DYNC1I1	4211
TRAPPC6B	4201
USO1	4192
NAPG	4190
EPS15	4189
EXOC5	4181
RAB9A	4177
COPZ1	4081
AP1G1	4052
RAB35	4030
VPS37B	3933
CLINT1	3903
RAB8A	3874
GGA3	3846
TBC1D13	3828
ARFGAP3	3807
KIF3B	3773
STX16	3771
KIF4A	3763
STON2	3698
EPS15L1	3688
TBC1D15	3678
AKT1	3656
SEC24B	3655
SCFD1	3593
RAB27B	3588
DNM1	3526
PIP5K1C	3436
NECAP2	3428
TBC1D16	3385
KIAA0319	3373
MYO1C	3351
ALB	3339
PUM1	3325
PPP6R3	3323
RAB3IP	3276
TBC1D24	3254
VAMP4	3236
ALS2	3234
DENND4B	3189
DENND6B	3049
RACGAP1	2921
KIF16B	2817
TMED3	2779
GCC1	2756
CFTR	2738
RALA	2686
STON1	2624
GAK	2606
EPGN	2579
KIF27	2576
CTSC	2547
VPS45	2526
TMF1	2524
COL1A2	2518
CHMP4A	2480
GOLGA1	2474
CSNK1D	2412
GGA1	2327
CHM	2291
TRIP10	2267
NECAP1	2247
ARRB1	2098
HSP90B1	2086
RABGAP1	2085
PRKAG2	1942
EREG	1906
COPS4	1865
AP1M2	1740
COPS6	1663
TFRC	1578
SFN	1557
ARF6	1407
TBC1D8B	1399
NAPA	1385
HSP90AA1	1348
PRKAB1	1302
STAM	1299
LRP2	1222
TF	1172
KIF6	1162
DTNBP1	1153
SEC31A	1144
UBA52	1071
CCZ1B	1066
COL4A2	979
KIF11	950
SCARF1	948
USE1	922
MSR1	823
KIF2C	812
VPS4A	776
CENPE	741
CNIH2	727
IGHV1-2	679
GJC2	662
STX4	626
TXNDC5	548
GJC1	538
CYTH2	456
SYT2	451
SEC16B	351
AKT2	345
SYS1	330
TMED10	328
AVPR2	306
WASL	283
ANKRD27	281
AP4M1	234
NBAS	195
IGHV2-5	174
IGHV3-53	122
APOE	103
TBC1D3	73
ZW10	37
COG4	15
EXOC8	-23
IGLC3	-37
TBC1D20	-49
HYOU1	-105
KIF18B	-123
VPS53	-130
GOSR1	-160
KIFC1	-166
IGKV1-39	-173
FNBP1	-320
IGKV5-2	-357
SNX9	-404
DENND6A	-405
COG8	-406
IGLV5-45	-419
IGHV3-7	-437
IGKV3-11	-446
SEC23IP	-469
IGHV3-48	-583
TRIP11	-591
BET1	-631
IGLV2-8	-740
TSC2	-804
IGHV1-46	-823
RAB12	-874
SCOC	-894
HPX	-915
IGKV1-5	-984
IGKV1-16	-990
IGHV3-23	-1042
KIF2A	-1080
IGKV1D-39	-1172
SCGB3A2	-1189
IGKV2D-28	-1291
IGHA2	-1293
IGLV7-46	-1341
CHML	-1348
MAN2A1	-1350
IGLV10-54	-1414
IGHV3-13	-1436
IGLV2-18	-1472
GOSR2	-1504
RAB7B	-1528
KIFC2	-1555
IGKV1-33	-1613
IGLV1-36	-1670
IGKV2-30	-1725
IGLV4-69	-1768
IGHA1	-1803
IGHV1-69	-1811
TOR1B	-1930
ARFGAP1	-1962
IGHV4-59	-1969
IGLV3-19	-2016
MAN1A2	-2017
IGKV3-15	-2034
FCHO1	-2036
IGHV3-11	-2041
CALM1	-2048
IGHV4-34	-2080
TSC1	-2097
KDELR3	-2154
IGHV3-30	-2221
AP1S2	-2330
TRAPPC2L	-2337
TRAPPC13	-2510
IGLV2-23	-2597
SEC24C	-2615
IGKV4-1	-2625
KIF18A	-2744
AP2B1	-2748
NAPB	-2763
IGLV2-11	-2782
IGKV1-17	-2799
IGKV3-20	-2824
IGLV6-57	-2876
IGHV3-33	-2989
MON1A	-3035
IGLV1-44	-3076
ARFIP2	-3098
SNX5	-3179
IGHV2-70	-3195
TPD52L1	-3229
KIF15	-3246
COG5	-3318
SPTBN5	-3449
VPS52	-3628
IGHV4-39	-3735
JCHAIN	-3826
RAB41	-3915
EPN2	-3979
IGKV3D-20	-4012
DENND5B	-4020
DYNLL2	-4042
GOLGA4	-4063
IGLV3-1	-4093
IGLV7-43	-4100
IGLV1-40	-4105
SH3D19	-4106
DCTN5	-4140
RALGAPB	-4157
COLEC12	-4188
IGKC	-4212
IGLV3-25	-4239
SEC22C	-4285
GBF1	-4322
IGLV1-51	-4413
IGLV3-21	-4455
GJA3	-4488
KIF26A	-4564
GPS1	-4577
IGLC7	-4779
ANK3	-4974
SEC22A	-5080
ARL1	-5130
ASPSCR1	-5158
SPTBN2	-5189
IGKV1-12	-5223
COG3	-5230
PIK3C2A	-5233
CD4	-5320
IGLC2	-5370
AP1G2	-5381
IGLV8-61	-5395
GOLGB1	-5425
DENND4A	-5472
SSC5D	-5500
IGLC1	-5548
AP1S3	-5592
AP4S1	-5732
IGKV2-28	-5778
IGLV1-47	-5810
ARFGAP2	-5850
COG6	-5872
IGLV3-27	-5935
ANKRD28	-6311
MIA3	-6330
MAN1C1	-6459
TJP1	-6461
RAB9B	-6471
GGA2	-6523
VPS51	-6565
SYT11	-6617
KIF28P	-6736
KIF21B	-6771
TRAPPC4	-6836
RPS27A	-6894
VPS36	-6942
REPS1	-7232
DENND1C	-7293
BICD1	-7322
AP4B1	-7350
BET1L	-7385
BLOC1S4	-7403
SPTBN1	-7419
YWHAQ	-7471
IGLV3-12	-7472
ARFRP1	-7488
TBC1D25	-7519
BNIP1	-7543
DENND4C	-7590
C2CD5	-7696
ALS2CL	-7707
GCC2	-7725
EXOC2	-7746
APOL1	-7788
DYNC1H1	-7822
KIF20B	-7903
COG2	-8023
PRKAB2	-8083
KLC4	-8231
KIF5C	-8297
CHMP7	-8325
CYTH3	-8377
KIF5A	-8378
IGLV2-14	-8416
DENND2A	-8504
SYNJ2	-8530
M6PR	-8665
TBC1D17	-8705
KLC2	-8724
KIFAP3	-8777
BLOC1S3	-8808
RAB38	-8811
TRAPPC2	-8851
COPS8	-8868
LDLRAP1	-8898
RAB30	-8959
SRC	-9011
CNIH3	-9196
HSPH1	-9227
AAK1	-9323
TPD52	-9423
DENND1B	-9482
TRAPPC10	-9516
NAA30	-9664
SYTL1	-9782
LNPEP	-9853
COPS7B	-9938
POLG	-9958
HIP1R	-10052
TBC1D4	-10161
RINT1	-10172
IL7R	-10324
RINL	-10520
SBF1	-10529
LMAN1	-10699
DVL2	-10753
HSPA8	-10913
TRAPPC6A	-10921
STX17	-11009
RAB33A	-11034
COPZ2	-11047
CD3D	-11094
BIN1	-11183
RHOBTB3	-11246
RAB39B	-11350
CD3G	-11409
SPTAN1	-11438
NAA35	-11460
HPS4	-11490
MYO6	-11522
TBC1D10C	-11564
KIF19	-11579
KIF26B	-11671
VAMP2	-11692
RABEP1	-11712
FZD4	-11733
OPTN	-11757
AKT3	-11804
SLC2A8	-11810
KIF21A	-11830
ADRB2	-11879
MADD	-11931
KIF3A	-11957
PLA2G6	-12020
TBC1D10A	-12038
COG1	-12057
SCARA5	-12080
DENND2D	-12158
CYTH1	-12174
KIF22	-12286
PACSIN1	-12327

---

Signal Transduction

	1069
set	Signal Transduction
setSize	1894
pANOVA	8.2e-28
s.dist	0.152
p.adjustANOVA	1.86e-25

Top enriched genes

GeneID	Gene Rank
CSF2RA	9574
PPARG	9571
WASF1	9568
EDNRB	9564
S100A9	9562
FZD5	9561
S100A8	9560
PLB1	9542
SOCS3	9526
XK	9525
HRH2	9509
GRB10	9508
CCR2	9503
GNA15	9499
ATP6V0A1	9483
CTSD	9475
LAMC1	9473
NUMB	9457
ADM	9454
LAMTOR1	9450

Click HERE to show all gene set members

GeneID	Gene Rank
CSF2RA	9574.0
PPARG	9571.0
WASF1	9568.0
EDNRB	9564.0
S100A9	9562.0
FZD5	9561.0
S100A8	9560.0
PLB1	9542.0
SOCS3	9526.0
XK	9525.0
HRH2	9509.0
GRB10	9508.0
CCR2	9503.0
GNA15	9499.0
ATP6V0A1	9483.0
CTSD	9475.0
LAMC1	9473.0
NUMB	9457.0
ADM	9454.0
LAMTOR1	9450.0
GPER1	9444.0
PRKACA	9441.0
GNG10	9436.0
GPR27	9426.0
H2AJ	9418.0
MYO7A	9417.0
RASGRP4	9405.0
PTAFR	9392.0
TACC3	9389.0
SNX3	9383.0
FPR1	9379.0
MMP9	9370.0
H2BC21	9368.0
NCF4	9365.0
FSTL3	9363.0
TNFRSF1A	9347.0
ARHGEF11	9346.0
RHOT1	9337.0
DUSP3	9324.0
GRB2	9320.0
YWHAG	9310.0
ARPC1B	9303.0
ATP6V1A	9301.0
ATP6V0D1	9298.0
GPR84	9292.0
FPR2	9282.0
FES	9280.0
CYFIP1	9270.0
KREMEN1	9259.0
WNT11	9251.0
SPTB	9250.0
TNS3	9238.0
CTNNA1	9237.0
PLA2G4A	9234.0
MAPK14	9219.0
FRAT2	9218.0
NCF2	9209.0
C5AR1	9205.0
ITSN1	9186.0
H2BC12	9178.0
RIT1	9174.0
TNFRSF10D	9167.0
FURIN	9162.0
CD55	9157.0
NCSTN	9139.0
RTN4	9135.0
UBE2D1	9125.0
APP	9123.0
CARM1	9122.0
ATP6V1D	9118.0
ATP6V0C	9113.0
ACVR1B	9110.0
PHC2	9103.0
ADCY3	9101.0
AGO4	9094.0
SYK	9087.0
RCOR1	9086.0
LRP1	9081.0
MAPK3	9078.0
VAPA	9073.0
DLG4	9070.0
FKBP1A	9066.0
PIK3CB	9065.0
ACTB	9060.0
HDAC4	9057.0
CLTC	9056.0
ALDH1A2	9044.0
TGFA	9031.0
GNAQ	9024.0
KL	9019.0
PRKCD	9012.0
YWHAE	9009.0
PROK2	9008.0
ATP6V1B2	9005.0
CYBB	9000.0
PLCB3	8999.0
STK3	8975.0
MAML3	8965.0
MAP2K1	8960.0
RHOU	8950.0
ITGA2B	8942.0
CRK	8941.0
CDC42EP3	8940.0
FKBP5	8936.0
ARPC1A	8923.0
ZDHHC9	8918.0
FOSL1	8911.0
STRADB	8888.0
ARHGAP18	8883.0
PLPPR2	8880.0
GNG5	8866.0
NTSR1	8865.0
MKRN1	8864.0
CCR1	8857.0
HGF	8856.0
LTB4R	8852.0
RRAGD	8850.0
APBB1IP	8849.0
OS9	8845.0
MEMO1	8843.0
PCSK6	8824.0
ARHGEF40	8800.0
FGD4	8799.0
BCL2L1	8798.0
CDKN2B	8797.0
FRAT1	8790.0
MARK3	8774.0
H3-3A	8754.0
RBPJ	8744.0
ADGRE1	8740.0
SUFU	8731.0
FOXO3	8729.0
RAC1	8720.0
UBE2D3	8710.0
ARHGDIB	8708.0
ADAM10	8705.0
ATP6V0B	8701.0
CDH5	8691.0
IQCE	8690.0
MYL6	8687.0
TLE3	8679.0
AP2M1	8673.0
ACTG1	8671.0
SNAI1	8669.0
CDK5	8663.0
ATP6V0E1	8662.0
JAG1	8661.0
ARPC5	8653.0
SOCS6	8639.0
ATP6V1C1	8628.0
ACVRL1	8625.0
RNF146	8622.0
YWHAH	8621.0
PRKAR1A	8616.0
BAMBI	8615.0
LAMTOR5	8611.0
ZDHHC7	8609.0
WAS	8596.0
OR2W3	8579.0
F2RL1	8568.0
TLN1	8554.0
RHOG	8544.0
PSMB7	8535.0
DLC1	8527.0
ARRB2	8517.0
PTEN	8516.0
ADORA2B	8515.0
TFDP1	8500.0
PSMD4	8498.0
RALB	8475.0
CLIP1	8474.0
RNF41	8473.0
SPINT1	8470.0
SMAD1	8465.0
PTGFR	8463.0
P4HB	8452.0
TNFRSF10B	8435.0
SPOPL	8429.0
ARHGAP26	8415.0
CLTA	8402.0
BAG4	8384.0
MRTFA	8376.0
WASF2	8373.0
ITGB3	8367.0
DIAPH2	8365.0
CAB39	8364.0
OMG	8356.0
SOS2	8350.0
TAX1BP3	8343.0
JAK3	8337.0
PSME3	8331.0
IRS2	8323.0
LYL1	8321.0
SP1	8315.0
ARPC3	8309.0
PPP2CA	8308.0
PPM1A	8296.0
FN1	8294.0
HEBP1	8289.0
ECE1	8287.0
C5AR2	8286.0
GNB1	8278.0
EGF	8267.0
B9D2	8262.0
TRIM27	8257.0
MAPKAPK3	8255.0
PAK1	8252.0
MKNK1	8248.0
ARAP3	8243.0
CFL1	8242.0
PPP3R1	8240.0
REEP4	8239.0
GNB2	8234.0
IL6R	8229.0
PAK2	8226.0
RAB6A	8223.0
RHOA	8218.0
WLS	8217.0
MOB1A	8214.0
SPINT2	8213.0
LIMK2	8190.0
IQGAP1	8189.0
PSMB5	8188.0
H2BC5	8163.0
STAT3	8152.0
KIF5B	8144.0
F11R	8139.0
PTPN12	8125.0
CAMKK2	8123.0
ATP6V1H	8119.0
ATP6V1E1	8107.0
INSR	8103.0
GAB2	8100.0
GNAI2	8094.0
DOK1	8092.0
MYD88	8091.0
EIF4G1	8081.0
AP2S1	8080.0
RHOBTB1	8077.0
H2BC11	8076.0
ATP2A2	8071.0
H2AC6	8070.0
C3AR1	8067.0
RAB4A	8050.0
WWP2	8046.0
PRKAR1B	8040.0
LYPLA1	8039.0
KDM4B	8038.0
ATP6AP1	8035.0
MEF2A	8030.0
P2RY13	8028.0
GNAI3	8027.0
EPN1	8026.0
VAV1	8021.0
GNAS	8019.0
PTK2B	8010.0
NOTCH3	8004.0
EPAS1	8002.0
RAF1	7991.0
TBL1X	7984.0
ADAM17	7980.0
NEDD4L	7972.0
FSTL1	7961.0
CHUK	7959.0
REEP5	7954.0
MAPK6	7952.0
NCOR2	7948.0
OPRL1	7943.0
P2RY1	7929.0
GMIP	7917.0
AKT1S1	7902.0
ACTR3	7888.0
PSMD6	7881.0
TFF3	7871.0
ARHGAP29	7864.0
DGKG	7861.0
SMAD6	7853.0
PSEN1	7843.0
PIK3AP1	7836.0
PTPRJ	7833.0
ACTR2	7827.0
ARAP1	7825.0
BEX3	7819.0
CSNK1A1	7813.0
GSK3A	7811.0
USP4	7809.0
RPS6KA1	7800.0
ARHGAP19	7799.0
RGS19	7795.0
SPTA1	7785.0
CASP9	7784.0
PPP2CB	7769.0
CSF2RB	7764.0
NDEL1	7753.0
SH2B2	7742.0
MGLL	7741.0
SH3GL1	7733.0
LYN	7728.0
TRIB1	7725.0
SPHK1	7724.0
MYL9	7719.0
PSMD9	7712.0
MAP3K11	7707.0
ZFYVE16	7706.0
LAMTOR2	7704.0
MAPRE1	7700.0
LAMTOR3	7692.0
RGS2	7686.0
LAMB3	7685.0
RHEB	7675.0
POLR2E	7660.0
CFLAR	7657.0
ADAP1	7645.0
CTNNBIP1	7635.0
PTPN2	7634.0
DYNC1I2	7629.0
PTCRA	7611.0
ARPC4	7605.0
RGL1	7604.0
CBL	7599.0
RUNX1	7591.0
UBE2M	7590.0
SERPINE1	7580.0
NCKAP1	7562.0
IER3	7557.0
H2BC4	7549.0
RGL2	7547.0
LRRK2	7543.0
CDC42	7539.0
ANXA1	7530.0
MAPK1	7520.0
NCKAP1L	7516.0
ARHGAP6	7514.0
RXRA	7513.0
NR1H2	7512.0
CCND3	7510.0
RHOQ	7504.0
H2BC17	7502.0
ARHGAP24	7497.0
PLEKHG2	7493.0
TEC	7488.0
KLHL12	7485.0
KLC3	7479.0
PSMD2	7470.0
PLTP	7453.0
ARPC2	7449.0
ROCK1	7445.0
NCF1	7433.0
DOCK1	7413.0
SPARC	7411.0
HIF1A	7404.0
FRS3	7402.0
FAM13A	7392.0
VEGFA	7389.0
VCL	7380.0
PLXND1	7376.0
SHOC2	7365.0
AP2A2	7360.0
PIK3R6	7359.0
IL1RAP	7349.0
PSMA1	7346.0
GDI2	7337.0
BCL2L11	7326.0
RAP1A	7319.0
OXER1	7318.0
RFNG	7317.0
PSMD1	7283.0
TCIRG1	7266.0
PSMB3	7265.0
DLD	7253.0
CXCL16	7237.0
PARD3	7225.0
FLT3	7222.0
RXFP2	7217.0
GTF2A2	7207.0
SRF	7205.0
LRP10	7198.0
TYK2	7192.0
PSMA7	7174.0
FFAR2	7172.0
DNM3	7167.0
EPOR	7164.0
BTK	7156.0
MOB1B	7155.0
ABI1	7154.0
GNB4	7138.0
THBS3	7134.0
CCRL2	7128.0
SPPL2A	7121.0
KIDINS220	7111.0
ADGRE2	7110.0
PSMC1	7096.0
PPP1CB	7093.0
BRK1	7085.0
GPR35	7077.0
TAB2	7070.0
VEGFC	7057.0
PRKCB	7056.0
RGS18	7049.0
DUSP1	7048.0
STAT5B	7011.0
TMED5	7010.0
PPP1R14A	7009.0
RGS14	7006.0
BAD	7002.0
PPP3CB	6998.0
GPSM3	6995.0
DYNC1LI1	6992.0
STAT5A	6983.0
VCP	6955.0
CYBA	6952.0
PSMB6	6927.0
CUL3	6924.0
ARHGEF17	6919.0
SPRED2	6917.0
RAPGEF2	6916.0
WASF3	6915.0
PSAP	6909.0
MAP2K2	6906.0
FLT1	6901.0
RALBP1	6894.0
JUNB	6889.0
TLE4	6882.0
PPP2R5B	6870.0
PRKG1	6867.0
STRAP	6850.0
DTX2	6845.0
CXCR1	6844.0
NFKBIA	6835.0
SEL1L	6834.0
PRKAR2B	6824.0
REEP3	6815.0
H3C15	6780.5
MYH9	6772.0
GFAP	6771.0
POLR2J	6769.0
NLN	6746.0
E2F3	6744.0
UBB	6737.0
GNAT2	6734.0
SRGAP1	6726.0
PSMF1	6724.0
GSK3B	6720.0
FFAR3	6709.0
PSMC6	6701.0
GRK6	6697.0
MYLK	6690.0
INSL3	6681.0
SDC4	6673.0
ST3GAL6	6671.0
ARHGEF2	6647.0
SREBF1	6642.0
AP2A1	6628.0
VPS26A	6625.0
VPS35	6616.0
GNG11	6612.0
VWF	6607.0
NEDD8	6597.0
LEPR	6590.0
KBTBD7	6566.0
FZD2	6552.0
USF2	6541.0
PSMD12	6537.0
PIP5K1B	6526.0
PREX1	6513.0
FOXO4	6493.0
MYO9B	6481.0
AHCYL1	6475.0
E2F1	6473.0
GRK3	6469.0
CTNNB1	6463.0
PDE3A	6461.0
RLN3	6445.0
OCRL	6436.0
CSNK2A2	6430.0
CAMKK1	6416.0
USP7	6410.0
LRP12	6407.0
YWHAB	6398.0
E2F4	6395.0
USP8	6383.0
NFKB1	6367.0
RARA	6365.0
RDH11	6355.0
RRAGA	6344.0
EEPD1	6343.0
PPP1CC	6334.0
PXN	6332.0
NEDD4	6330.0
LDLR	6329.0
PPP3CA	6327.0
ELMO1	6324.0
SIRT6	6321.0
PSMD11	6296.0
ARHGAP9	6288.0
IQGAP2	6286.0
OR52K1	6285.0
RGL3	6283.0
PRKAR2A	6265.0
APH1B	6248.0
DTX4	6230.0
SH3KBP1	6227.0
RGS16	6219.0
PDPK1	6209.0
EP300	6208.0
CSNK2A1	6207.0
RGS6	6201.0
PIP5K1A	6198.0
CLTB	6195.0
STAM2	6183.0
SHB	6181.0
FOS	6179.0
PTPN6	6176.0
ABR	6165.0
DNM2	6163.0
IRAK1	6159.0
ARHGDIA	6155.0
ROCK2	6151.0
FNTB	6148.0
GRK2	6141.0
ITGAV	6133.0
PPP1R12A	6131.0
H2AZ1	6126.0
EIF4EBP1	6124.0
FABP5	6123.0
ARHGEF37	6112.0
AMOTL1	6101.0
TMED2	6098.0
PIK3CD	6096.0
LPAR2	6093.0
PDGFC	6090.0
HDAC7	6070.0
ABCA1	6066.0
DYNLL1	6049.0
LATS2	6044.0
PPP1R15A	6033.0
IGF1R	6032.0
OPN3	6030.0
PPBP	6029.0
USP15	6028.0
PSMD7	6017.0
PDGFRA	6002.0
CTTN	5999.0
PTK6	5998.0
BAX	5996.0
PSMD13	5991.0
ASH2L	5989.0
PPP2R5A	5985.0
TAX1BP1	5982.0
NCOR1	5979.0
PSMA6	5978.0
SHARPIN	5976.0
ADORA3	5974.0
P2RY2	5954.0
STAT6	5950.0
ATP6V1F	5949.0
LAMB1	5948.0
THBS1	5946.0
PTPN18	5944.0
ADM2	5935.0
ST3GAL4	5930.0
ITPR2	5919.0
RANBP9	5914.0
DAGLB	5909.0
GNA13	5903.0
KEL	5891.0
ARHGAP27	5890.0
OR2L2	5880.0
PDK4	5854.0
CXCR2	5851.0
PSMD8	5845.0
GRIN2D	5844.0
CDC42EP2	5839.0
PSENEN	5833.0
SRGAP2	5824.0
PDE1B	5822.0
RNF111	5821.0
SEC13	5820.0
GDI1	5807.0
MAF1	5804.0
PTPN1	5797.0
ATF1	5790.0
APOA2	5784.0
PF4	5777.0
ATP6V1E2	5776.0
WIPF2	5769.0
PDE4C	5759.0
FADD	5746.0
SUCNR1	5739.0
SOX6	5735.0
DVL3	5734.0
GAB1	5723.0
TAB1	5711.0
PLXNB1	5690.0
YWHAZ	5687.0
AGO1	5660.0
LPAR1	5653.0
KLC1	5596.0
ECT2	5587.0
PRKAG1	5582.0
OR2T33	5578.0
HDAC2	5569.0
PFN1	5562.0
ARHGAP23	5543.0
USP9X	5542.0
PAFAH1B1	5534.0
CBX8	5523.0
CXCL1	5516.0
CXCL2	5509.0
GTF2F2	5503.0
AREG	5494.0
OR2B11	5485.0
PDGFA	5484.0
TAOK1	5471.0
H2BC9	5461.0
H2BC15	5458.0
MAML1	5447.0
ARHGAP31	5445.0
IKBKG	5434.0
PSMA2	5433.0
NSL1	5429.0
NRAS	5411.0
PTPN11	5383.0
POLR2L	5362.0
BRAP	5352.0
S1PR3	5343.0
STAG2	5339.0
PDE6D	5327.0
CSK	5285.0
NOTCH2	5276.0
HNRNPM	5258.0
SDC2	5257.0
SNW1	5255.0
RAC2	5238.0
ADCY4	5226.0
GPR37L1	5222.0
TGFB1	5201.0
CALCRL	5199.0
COL9A3	5186.0
PBX1	5182.0
MYL12B	5177.0
CPT1A	5153.0
TBXA2R	5139.0
MAPKAP1	5130.0
ARHGAP30	5105.0
PLCG2	5103.0
CDC73	5093.0
ANOS1	5079.0
PIK3R2	5051.0
GTF2F1	5042.0
H2AC20	5039.0
ARHGAP21	5034.0
RRAGC	5033.0
P2RY12	5031.0
CDC25C	5024.0
NCK2	5007.0
VAV3	4974.0
KDM1B	4958.0
CHN2	4944.0
SMAD2	4939.0
CXCL3	4925.0
F2RL3	4924.0
AR	4913.0
USF1	4893.0
EIF4E	4892.0
PCSK5	4881.0
HBEGF	4878.0
SOX4	4870.0
COL6A3	4861.0
ID1	4819.0
HDAC11	4790.0
SMARCA4	4789.0
HDAC5	4761.0
PPID	4758.0
WNT6	4753.0
BIRC2	4749.0
GRAP2	4746.0
LIMK1	4741.0
HDAC3	4734.0
NOTCH1	4733.0
RGS10	4704.0
IFT122	4701.0
PIK3CA	4697.0
PLCB2	4696.0
PSMD3	4693.0
PPP2R1A	4669.0
CNR1	4666.0
ARHGAP1	4662.0
GPSM2	4651.0
POLR2F	4646.0
SGK1	4642.0
TBL1XR1	4627.0
LRP8	4619.0
NRIP1	4616.0
CAV2	4602.0
FZD1	4601.0
HGS	4570.0
NCOA1	4563.0
GAS8	4542.0
OR6C75	4532.0
FGD2	4526.0
AATF	4511.0
ELMO2	4507.0
PTK2	4506.0
SHC2	4499.0
LAMTOR4	4487.0
PTGER3	4459.0
DIAPH3	4446.0
CDKN1A	4438.0
SEM1	4436.0
KCTD6	4434.0
S1PR4	4426.0
UBC	4421.0
NMT1	4400.0
DUSP6	4367.0
GPR65	4364.0
B4GALT1	4354.0
SKP1	4349.0
PDHX	4344.0
GNG8	4339.0
PDHB	4292.0
PDK1	4269.0
CENPA	4259.0
DYNC1LI2	4253.0
LRP5	4241.0
CRHBP	4234.0
DYNC1I1	4211.0
APH1A	4198.0
FMNL1	4191.0
EPS15	4189.0
HCAR2	4186.0
TJP2	4183.0
PTGES3	4180.0
MDM2	4179.0
MAPKAPK2	4176.0
SHC1	4173.0
ITGA2	4159.0
PPP1CA	4156.0
RCVRN	4149.0
CTBP2	4142.0
CDC37	4125.0
SQSTM1	4123.0
KSR1	4113.0
GOLGA7	4109.0
SCD	4108.0
PSMB2	4103.0
CBX6	4091.0
PAG1	4088.0
CDC20	4087.0
BIRC5	4082.0
SHC3	4054.0
RBX1	4039.0
NRG1	4018.0
IL6ST	3996.0
ATP6V1G1	3989.0
CSNK2B	3987.0
CRKL	3986.0
HNRNPF	3972.0
JUN	3964.0
MAP2K5	3957.0
MAPK11	3955.0
MMP7	3952.0
C5	3932.0
SH2B3	3920.0
SOCS1	3886.0
TGFBR2	3881.0
STARD8	3858.0
GGA3	3846.0
DHRS4	3835.0
CXCL5	3815.0
WDR83	3802.0
ZRANB1	3772.0
KRAS	3760.0
STRN	3758.0
FAS	3710.0
MAPK13	3704.0
EPS15L1	3688.0
FGF2	3660.0
PHLPP1	3657.0
AKT1	3656.0
HSD17B1	3651.0
OR2V2	3611.0
DAAM1	3591.0
POLR2G	3581.0
RNF2	3573.0
NCOA3	3563.0
NPFFR1	3557.0
DNM1	3526.0
IQGAP3	3509.0
PSMD5	3507.0
INHBA	3489.0
BMPR2	3487.0
OR10G3	3485.0
NLK	3472.0
FFAR4	3462.0
CREBBP	3460.0
RLBP1	3457.0
OR2C3	3449.0
PIP5K1C	3436.0
AKAP13	3430.0
PSMB1	3422.0
FGD3	3417.0
BUB1	3411.0
PMF1	3407.0
GNA12	3399.0
DNAL4	3391.0
CGN	3379.0
RGR	3371.0
KIF14	3370.0
GNAI1	3364.0
PDE11A	3338.0
RAP1B	3331.0
KTN1	3322.0
PDK3	3304.0
APC	3284.0
OR8A1	3282.0
STARD13	3273.0
ZNF217	3266.0
KMT2D	3244.0
GNA11	3239.0
RAB4B	3231.0
ARHGEF12	3230.0
ADORA2A	3227.0
VPS29	3218.0
DLGAP5	3185.0
RPS6KA2	3177.0
RGS17	3173.0
YBX1	3172.0
TAB3	3165.0
NUP37	3153.0
HDAC8	3141.0
GATAD2A	3125.0
NUP98	3124.0
AVPR1A	3123.0
NF1	3113.0
ABCG8	3112.0
BUB1B	3104.0
DERL2	3093.0
KLK2	3082.0
DHRS9	3076.0
PLK1	3065.0
AGO2	3046.0
GLI1	3041.0
NTRK3	3038.0
RPS6KA3	3012.0
MTMR4	2986.0
POMC	2971.0
EGR1	2965.0
CCNK	2936.0
GNAZ	2927.0
KHDRBS1	2926.0
RACGAP1	2921.0
CETP	2908.0
PSPN	2902.0
TNFSF10	2887.0
CENPF	2876.0
SLC38A9	2861.0
LPL	2853.0
ARHGAP28	2800.0
SKA1	2798.0
RAMP3	2787.0
OR2G6	2776.0
OR7D4	2770.0
LGR4	2759.0
GTF2A1	2744.0
CFTR	2738.0
HPN	2719.0
PSMD14	2703.0
PSMC2	2696.0
RALA	2686.0
ARAF	2680.0
ARHGAP32	2659.0
IL1RL1	2644.0
NDE1	2635.0
JAK2	2599.0
EPGN	2579.0
ANGPT1	2578.0
RANBP10	2565.0
PSMB4	2552.0
SDC3	2535.0
OR52A1	2522.0
PLPPR3	2515.0
MECOM	2503.0
PTPRO	2485.0
ARHGEF6	2483.0
ADRA2A	2476.0
OR7C1	2456.0
MAP3K7	2453.0
PPP2R5D	2440.0
OR51L1	2429.0
OR2H2	2421.0
SPC24	2393.0
OR2M4	2379.0
MYC	2367.0
STRADA	2359.0
SMPD2	2340.0
GRPR	2328.0
HDAC10	2302.0
SFPQ	2294.0
TRIP10	2267.0
PRICKLE1	2258.0
STK11	2241.0
RBCK1	2239.0
CBX4	2237.0
WNT9B	2201.0
MT-RNR2	2190.0
OPRM1	2186.0
GRK4	2167.0
CBFB	2152.0
GREM2	2139.0
RASA1	2134.0
POFUT1	2133.0
ATF2	2110.0
ARRB1	2098.0
MCF2	2087.0
TSHR	2057.0
PIK3CG	2046.0
PSMC3	2018.0
GALNT3	2006.0
HCAR3	1970.0
PRKAG2	1942.0
EREG	1906.0
OR2M3	1898.0
CAMK2G	1888.0
CCNC	1883.0
ACKR2	1880.0
CAV1	1856.0
SPRY1	1831.0
TRIO	1829.0
DEPDC1B	1822.0
OR5AU1	1814.0
IRS1	1806.0
CXCL8	1797.0
TNFRSF10A	1785.0
CNGB1	1779.0
FER	1777.0
HSPB1	1738.0
PPP1R12B	1737.0
ARHGAP11A	1723.0
RAD21	1719.0
RGS3	1680.0
CDC14B	1667.0
PSMD10	1646.0
TGFBR1	1642.0
NPHP4	1633.0
PIK3C3	1626.0
POU2F1	1611.0
JUND	1561.0
SFN	1557.0
ARHGAP22	1541.0
POLR2C	1531.0
CDK1	1480.0
XIAP	1478.0
PTGER2	1451.0
TERT	1447.0
OR1D2	1442.0
FOSB	1432.0
QRFP	1421.0
PDE4D	1410.0
ARF6	1407.0
ITCH	1394.0
KAT5	1361.0
PRKAA1	1352.0
HSP90AA1	1348.0
HDAC9	1347.0
NAB1	1315.0
BRAF	1314.0
PRKAB1	1302.0
TACR2	1300.0
STAM	1299.0
VRK3	1293.0
COL4A3	1268.0
SSTR2	1258.0
OR14L1P	1247.0
EIF4B	1233.0
PLCB1	1225.0
LRP2	1222.0
ARHGAP4	1202.0
WWC1	1194.0
RHOB	1190.0
SPOP	1174.0
TF	1172.0
OR56A1	1165.0
PRKCA	1163.0
OR1I1	1152.0
PRC1	1119.0
NCOA2	1109.0
UBA52	1071.0
DACT1	1044.0
RIPK2	1042.0
ELK1	1040.0
APOD	1010.0
RBBP5	1009.0
SYVN1	997.0
GABRG2	992.0
COL4A2	979.0
SAG	976.0
DEPDC7	971.0
AURKB	959.0
REST	945.0
CSNK1G2	899.0
GNG3	894.0
GNAT1	874.0
CUL5	847.0
KIF2C	812.0
MST1	808.0
FKBP4	788.0
LRP6	787.0
EVC	785.0
ERLEC1	775.0
FUZ	749.0
CENPE	741.0
TIAM1	701.0
ELF3	676.0
MYH10	663.0
SAV1	661.0
SMC1A	659.0
RPS6KB2	652.0
CHD8	642.0
RDH5	602.0
NR3C1	600.0
WIPF1	581.0
MYB	555.0
FLNA	547.0
YY1	529.0
CAMKMT	506.0
LAMB2	494.0
RETSAT	493.0
ST3GAL3	485.0
GNB5	467.0
TAS2R14	464.0
APOM	422.0
ADGRE3	396.0
HDAC1	394.0
IL33	392.0
NELFB	385.0
LTB4R2	379.0
AKT2	345.0
KREMEN2	321.0
NCKIPSD	320.0
POLR2I	316.0
REEP1	309.0
AVPR2	306.0
ATN1	305.0
MLST8	304.0
WASL	283.0
AKR1C1	280.0
TCF7L1	265.0
GALR1	235.0
ABL1	229.0
ARHGAP15	215.0
KISS1R	173.0
TNS4	165.0
PKN2	151.0
ADCY9	146.0
RACK1	127.0
RASAL2	112.0
APOE	103.0
FRK	94.0
LEO1	84.0
DVL1	61.0
KDM4A	38.0
ZW10	37.0
RAPGEF3	25.0
CENPN	24.0
CHD1	-6.0
HCAR1	-31.0
ABHD17B	-38.0
PTPN3	-46.0
ITGB1	-50.0
CD86	-71.0
CXCR4	-125.0
WNT5B	-129.0
PRKCI	-135.0
OR10AC1	-140.0
BAIAP2	-179.0
PTBP1	-195.0
PARD6A	-224.0
OR2AT4	-237.0
TRAF6	-241.0
SRMS	-242.0
STK4	-243.0
PPP2R1B	-246.0
METAP2	-247.0
MEF2C	-319.0
NBEA	-347.0
OR4K17	-356.0
KNL1	-360.0
XCR1	-370.0
ERCC6L	-418.0
ACTA2	-430.0
GPR132	-440.0
ERBB3	-468.0
MAML2	-476.0
CAB39L	-486.0
SYDE2	-491.0
CASP3	-499.0
TNKS2	-512.0
DGKD	-515.0
PSMA4	-538.0
MBD3	-546.0
TRADD	-548.0
CLASP1	-573.0
OXTR	-584.0
ERBIN	-585.0
SKIL	-606.0
PPP2R5E	-627.0
ARL2	-643.0
GPNMB	-660.0
OR4D9	-671.0
NUDC	-674.0
GPR83	-685.0
RRAGB	-689.0
EGR3	-690.0
FASN	-702.0
DIAPH1	-704.0
OTULIN	-705.0
PDE2A	-735.0
CCR10	-736.0
ICMT	-766.0
RASAL1	-777.0
TSC2	-804.0
RANBP2	-808.0
CORT	-899.0
LAMA1	-906.0
GPS2	-914.0
GRK5	-923.0
USP34	-934.0
MAPK12	-946.0
PSMC5	-948.0
OPHN1	-952.0
ATP2A3	-999.0
AGO3	-1014.0
OR7G2	-1026.0
KIF2A	-1080.0
STUB1	-1093.0
PDE6G	-1098.0
TAS1R3	-1110.0
PPEF1	-1146.0
CDK5R1	-1166.0
BCL9	-1175.0
ARHGAP44	-1179.0
NMB	-1180.0
ROR1	-1182.0
XPO1	-1199.0
PLAT	-1233.0
H2AZ2	-1266.0
TCF12	-1268.0
COL6A1	-1276.0
OR5A1	-1290.0
MAPK7	-1294.0
NSMAF	-1313.0
GRM6	-1316.0
CREB1	-1382.0
OR10A6	-1386.0
CRABP2	-1473.0
SEPTIN7	-1544.0
IFT52	-1548.0
DUSP10	-1587.0
AHCTF1	-1621.0
PCP2	-1632.0
OR7D2	-1642.0
NOS3	-1718.0
ADCY6	-1746.0
PDE7B	-1760.0
GATAD2B	-1780.0
POLR2K	-1792.0
LATS1	-1798.0
RELA	-1807.0
ZNRF3	-1808.0
IFT57	-1813.0
CDCA8	-1850.0
RBBP4	-1907.0
F2RL2	-1922.0
NRG4	-1939.0
TRPC6	-1948.0
ABHD17C	-1955.0
SMC3	-1982.0
PKN1	-1986.0
CDK8	-1997.0
PLG	-1998.0
LRRC7	-2007.0
GABRB3	-2011.0
CALM1	-2048.0
LAMC3	-2093.0
TSC1	-2097.0
EGR2	-2130.0
OR10H5	-2153.0
LAMA4	-2162.0
ABHD6	-2164.0
CLASP2	-2169.0
GNG4	-2175.0
PDE6A	-2208.0
IFT88	-2216.0
ATP6V1C2	-2222.0
GABBR1	-2258.0
TIAL1	-2300.0
OR7A5	-2311.0
PIP4K2A	-2339.0
PIK3R5	-2346.0
PFN2	-2375.0
KAT2B	-2393.0
DOCK7	-2432.0
SUZ12	-2444.0
HTR7	-2465.0
CASP2	-2478.0
ADGRE5	-2501.0
SOX7	-2523.0
CHEK1	-2534.0
POLR2B	-2536.0
SMURF1	-2584.0
OR1C1	-2627.0
OR4E1	-2654.0
NEURL1B	-2658.0
PTPRU	-2718.0
KIF18A	-2744.0
AP2B1	-2748.0
OR1M1	-2775.0
GNB3	-2776.0
POLR2H	-2817.0
RXFP4	-2822.0
SCRIB	-2871.0
ADCY2	-2874.0
FGFR4	-2892.0
WNT8B	-2910.0
MTA1	-2917.0
DTX1	-2958.0
OR6Y1	-2967.0
MIB1	-2999.0
NGFR	-3013.0
LAMA5	-3030.0
PHB	-3050.0
NUP85	-3077.0
PSMB8	-3080.0
POLR2A	-3105.0
CCL3	-3120.0
MEF2D	-3132.0
OR7A17	-3161.0
CENPI	-3165.0
DGKH	-3171.0
RXRB	-3221.0
PDE4A	-3250.0
DUSP7	-3253.0
ARHGEF38	-3267.0
PIN1	-3272.0
RAC3	-3292.0
ADCY7	-3307.0
OR1A1	-3308.0
PMEPA1	-3325.0
HRAS	-3335.0
SGO2	-3359.0
KSR2	-3364.0
ARHGAP35	-3408.0
NR1H3	-3418.0
FRS2	-3430.0
RPS6KB1	-3433.0
ETV4	-3440.0
SPTBN5	-3449.0
OR2A5	-3467.0
LPAR6	-3477.0
MYH11	-3490.0
CASP10	-3491.0
PLIN1	-3507.0
DLAT	-3566.0
GPC2	-3613.0
COL4A4	-3622.0
FLRT2	-3651.0
MDK	-3656.0
FCER2	-3678.0
AAMP	-3695.0
PKN3	-3714.0
KALRN	-3725.0
CD19	-3769.0
FMNL2	-3776.0
ARHGEF26	-3778.0
DAB2IP	-3780.0
TAS2R30	-3794.0
OR6K3	-3809.0
LIN7B	-3872.0
TCF4	-3878.0
UHMK1	-3901.0
KANK1	-3909.0
ARHGEF4	-3912.0
LINC01139	-3916.0
OR5AN1	-3918.0
PAQR3	-3952.0
NRP2	-3980.0
WNT2B	-3983.0
CDK9	-3988.0
FGF7	-3999.0
MYLIP	-4005.0
INTU	-4006.0
PIK3R4	-4040.0
DYNLL2	-4042.0
ARHGEF10	-4043.0
RING1	-4045.0
POLR2D	-4058.0
VAV2	-4073.0
MED1	-4082.0
PAK3	-4194.0
DOCK3	-4198.0
AMH	-4200.0
UCN	-4308.0
NUF2	-4325.0
HTR6	-4345.0
SPPL2B	-4346.0
RASA2	-4348.0
TAS2R3	-4387.0
IFT140	-4407.0
RHPN2	-4434.0
ATP2A1	-4436.0
RDH10	-4447.0
BCL2	-4480.0
CNKSR2	-4481.0
PDHA1	-4484.0
CCR9	-4486.0
OPRD1	-4494.0
WNT4	-4524.0
MCHR1	-4527.0
PTPRA	-4528.0
TAS2R20	-4540.0
ARHGEF35	-4546.0
PTCH2	-4548.0
WNT9A	-4557.0
TNRC6B	-4558.0
CPT1B	-4560.0
CHD4	-4576.0
ARHGEF7	-4627.0
SMAD5	-4675.0
CBX2	-4693.0
RCE1	-4695.0
GPC1	-4697.0
GPC4	-4718.0
WNT3	-4740.0
PNOC	-4750.0
ZWINT	-4758.0
MAMLD1	-4791.0
RHPN1	-4792.0
RARG	-4816.0
OR14J1	-4824.0
ADAM12	-4836.0
SPRY2	-4863.0
WNT16	-4891.0
BTRC	-4932.0
GUCA1B	-4944.0
CRHR2	-4975.0
RGS5	-4998.0
CIT	-5008.0
HRH1	-5012.0
CDK2	-5018.0
S100B	-5025.0
MAD1L1	-5035.0
GNG7	-5049.0
SMAD9	-5098.0
TIA1	-5138.0
EFCAB7	-5139.0
CCNT2	-5173.0
KHDRBS2	-5182.0
SPTBN2	-5189.0
RCC2	-5199.0
NOTCH4	-5200.0
CENPO	-5215.0
IKBKB	-5290.0
PSMA3	-5314.0
GPSM1	-5321.0
REEP2	-5330.0
FGFR1	-5335.0
PTENP1	-5342.0
CENPM	-5373.0
RHOT2	-5408.0
TCF7L2	-5419.0
ARHGAP33	-5429.0
ARHGEF1	-5462.0
RGS1	-5499.0
NOXA1	-5532.0
JUP	-5541.0
SCMH1	-5553.0
TNRC6A	-5567.0
DLG2	-5599.0
RHOBTB2	-5623.0
DNAJB1	-5625.0
NEFL	-5629.0
RASGEF1A	-5631.0
DGKZ	-5636.0
MST1R	-5647.0
HRH4	-5658.0
PGF	-5699.0
FNTA	-5702.0
SOS1	-5714.0
SCUBE2	-5729.0
SRGAP3	-5738.0
TAS2R5	-5753.0
GPR161	-5767.0
PSMB10	-5768.0
MUC20	-5791.0
TLE2	-5817.0
STAP2	-5832.0
MRAS	-5840.0
NCBP1	-5866.0
TRIB3	-5896.0
TLR9	-5909.0
MFNG	-5940.0
SEH1L	-5957.0
SALL4	-5965.0
HNRNPA1	-5998.0
SORCS3	-6008.0
EVC2	-6025.0
OBSCN	-6026.0
INCENP	-6043.0
ARHGEF10L	-6066.0
PPARD	-6092.0
OR5A2	-6094.0
PSME4	-6099.0
RPS6	-6100.0
VIPR1	-6107.0
PSMA5	-6154.0
WWTR1	-6206.0
ZDHHC21	-6207.0
OR2A7	-6218.0
UTS2B	-6250.0
CKAP5	-6299.0
LPAR3	-6366.0
FZD6	-6395.0
OR2A1	-6398.0
PTPRK	-6407.0
STAG1	-6429.0
DUSP4	-6432.0
ARHGEF5	-6441.0
CENPQ	-6451.0
PDE8B	-6452.0
TJP1	-6461.0
FOXO6	-6467.0
CHRM5	-6487.0
CENPU	-6495.0
FZD7	-6496.0
RRH	-6503.0
H2BU1	-6519.0
CTBP1	-6549.0
RET	-6557.0
NF2	-6614.0
DUSP16	-6652.0
ARHGEF18	-6672.0
GPR15	-6674.0
USP21	-6692.0
HSP90AB1	-6702.0
FBXW7	-6709.0
OR5AS1	-6720.0
USP13	-6723.0
RASGRF1	-6738.0
TRRAP	-6755.0
NR4A1	-6762.0
FZD3	-6817.0
SGO1	-6826.0
CASR	-6833.0
CD80	-6837.0
FGF23	-6840.0
KPNA2	-6845.0
CCND1	-6847.0
PDE8A	-6850.0
CNKSR1	-6858.0
ACVR1C	-6866.0
GRK7	-6867.0
RPS27A	-6894.0
INPP5B	-6905.0
DRAP1	-6924.0
PEA15	-6947.0
SPRED3	-6979.0
GREB1	-6981.0
NAPEPLD	-6983.0
TLE1	-7036.0
TRAT1	-7043.0
TAS2R4	-7045.0
NOG	-7057.0
CCR6	-7086.0
CCR7	-7088.0
WDR19	-7155.0
BCR	-7186.0
ALDH8A1	-7195.0
GNAL	-7208.0
DISP2	-7227.0
PDE4B	-7228.0
WNT7A	-7231.0
FZD8	-7237.0
TNF	-7241.0
ACKR4	-7245.0
LEF1	-7246.0
CXXC5	-7252.0
GPBAR1	-7268.0
FLT4	-7288.0
IL2RA	-7301.0
CDON	-7341.0
RBFOX2	-7354.0
MTA2	-7367.0
SPTBN1	-7419.0
ARHGAP39	-7429.0
AXIN2	-7434.0
YWHAQ	-7471.0
RTP5	-7505.0
NET1	-7542.0
ITPR1	-7553.0
PSMA8	-7559.0
PPP5C	-7588.0
DGKA	-7619.0
ITGB3BP	-7623.0
CNR2	-7625.0
ARHGAP12	-7661.0
ZFYVE9	-7706.0
HSPG2	-7708.0
ARHGAP42	-7711.0
PIP4K2B	-7720.0
HES1	-7731.0
CXXC4	-7734.0
ARHGAP11B	-7750.0
IKZF1	-7757.0
NTRK1	-7791.0
CYSLTR1	-7801.0
ADRB1	-7803.0
CCR8	-7805.0
GNG2	-7809.0
PHC1	-7816.0
SCAI	-7817.0
DYNC1H1	-7822.0
HNRNPH1	-7827.0
NUP133	-7839.0
PSEN2	-7844.0
GHSR	-7846.0
VEGFB	-7866.0
ARHGAP17	-7883.0
RLN2	-7910.0
KNTC1	-7922.0
OR2I1P	-7924.0
MCF2L	-7933.0
UCHL5	-7955.0
EDN3	-7958.0
DYNC2H1	-8016.0
PRKCE	-8024.0
CHN1	-8061.0
ABCG1	-8065.0
PLEKHG5	-8069.0
MAD2L1	-8081.0
PRKAB2	-8083.0
PDK2	-8114.0
RASGRP2	-8137.0
PHC3	-8154.0
GLI3	-8180.0
BMPR1A	-8182.0
KLC4	-8231.0
DGKQ	-8252.0
MEN1	-8265.0
SMAD4	-8273.0
RAMP1	-8282.0
CDKN1B	-8305.0
E2F5	-8308.0
ADCY5	-8315.0
DLG1	-8338.0
SH2B1	-8341.0
HDAC6	-8348.0
KIF5A	-8378.0
METAP1	-8406.0
MAPKAPK5	-8452.0
CENPK	-8469.0
GNRH1	-8490.0
LFNG	-8502.0
CILP	-8503.0
CTNND1	-8519.0
WNT1	-8531.0
THBS4	-8534.0
PRKG2	-8538.0
PDGFB	-8575.0
ARHGAP25	-8588.0
GNRHR2	-8598.0
RDH16	-8616.0
ID3	-8629.0
SPRED1	-8664.0
TGIF1	-8667.0
UTS2	-8671.0
STMN1	-8695.0
ARHGEF19	-8700.0
KLC2	-8724.0
RUVBL1	-8726.0
DAGLA	-8730.0
FGF22	-8733.0
SYNGAP1	-8744.0
CENPH	-8745.0
TPH1	-8787.0
GFRA2	-8804.0
GPR55	-8824.0
TNKS	-8839.0
ARHGAP5	-8857.0
ICOS	-8862.0
ESRP2	-8869.0
CXCR5	-8871.0
NRP1	-8872.0
FGF9	-8873.0
PML	-8888.0
PRMT1	-8894.0
BCO2	-8895.0
MTA3	-8918.0
RASGRP3	-8923.0
ARHGAP10	-8936.0
TRIM33	-8937.0
SKA2	-8943.0
CCR5	-8977.0
SRC	-9011.0
CYLD	-9037.0
HHAT	-9053.0
GUCY2D	-9066.0
CYSLTR2	-9085.0
RYK	-9116.0
NDC80	-9117.0
ADORA1	-9135.0
FOXO1	-9173.0
CAMK4	-9185.0
POGLUT1	-9193.0
FGFBP3	-9205.0
TBP	-9220.0
ESR1	-9230.0
ESR2	-9236.0
S1PR1	-9239.0
ATP6V1G2	-9275.0
PSMC4	-9306.0
NFATC1	-9315.0
PTGIR	-9321.0
EDN1	-9338.0
FLT3LG	-9400.0
OR4D1	-9402.0
CENPT	-9416.0
EED	-9417.0
CHD3	-9466.0
SSTR3	-9470.0
KDM1A	-9476.0
CYP4V2	-9514.0
WNT10A	-9536.0
TRPC3	-9546.0
RASGRF2	-9554.0
CCNT1	-9570.0
DUSP2	-9580.0
RICTOR	-9593.0
NUP43	-9595.0
XCL1	-9598.0
MYO9A	-9616.0
CLIP3	-9620.0
NCBP2	-9624.0
MAPK8	-9646.0
RPS27	-9651.0
GAS1	-9660.0
GHRL	-9675.0
TCF7	-9694.0
GOPC	-9696.0
OR52N4	-9699.0
GRAP	-9703.0
PIK3R1	-9725.0
WNT10B	-9743.0
BMI1	-9787.0
DDX5	-9806.0
A2M	-9822.0
RGS9	-9835.0
F2R	-9847.0
CD28	-9858.0
CBY1	-9898.0
HEY2	-9918.0
LAMA2	-9923.0
EZH2	-9929.0
CCR4	-9939.0
TGIF2	-9946.0
MTOR	-9948.0
ITPR3	-9955.0
COL9A2	-9974.0
PORCN	-9992.0
GPAM	-9993.0
ACKR3	-9999.0
GPR150	-10012.0
RPGRIP1L	-10013.0
RAPGEF1	-10033.0
WWP1	-10036.0
CDC14A	-10085.0
RBL1	-10115.0
GNAO1	-10133.0
PSME1	-10138.0
LRIG1	-10216.0
CSNK1E	-10239.0
SMURF2	-10250.0
RDH14	-10270.0
PRDM4	-10287.0
PDE7A	-10299.0
REEP6	-10309.0
AXIN1	-10310.0
MIR25	-10321.0
EBAG9	-10325.0
NAB2	-10348.0
RNF31	-10362.0
KAT2A	-10374.0
NUP160	-10383.0
COL6A2	-10386.0
CYFIP2	-10387.0
PSME2	-10415.0
WDR35	-10420.0
ACVR2B	-10439.0
RHOH	-10460.0
MKS1	-10466.0
PLCG1	-10473.0
RPTOR	-10494.0
MIS12	-10502.0
DGKK	-10512.0
KDM4C	-10513.0
PRKX	-10527.0
NUP107	-10570.0
ABHD12	-10579.0
ITGA3	-10589.0
OTUD3	-10628.0
FAM13B	-10669.0
CXCL9	-10691.0
RDH13	-10697.0
GPR25	-10714.0
XCL2	-10744.0
DVL2	-10753.0
IFT172	-10757.0
ABHD17A	-10780.0
CX3CR1	-10809.0
BIRC3	-10830.0
MC1R	-10836.0
PELP1	-10841.0
ABI2	-10893.0
PYGO2	-10903.0
CCL28	-10904.0
TP53	-10936.0
DSN1	-10945.0
DRD4	-10976.0
SKI	-10980.0
P2RY11	-10982.0
THEM4	-10987.0
CCR3	-10997.0
ARHGEF39	-11011.0
ID2	-11019.0
PTPN7	-11022.0
KIT	-11031.0
MIB2	-11044.0
JAK1	-11075.0
OFD1	-11087.0
AMER1	-11097.0
P2RY6	-11110.0
EEF2K	-11125.0
TNFAIP3	-11131.0
LPAR5	-11136.0
CDK4	-11138.0
WWOX	-11144.0
TIAM2	-11149.0
CCL5	-11152.0
PDE6B	-11155.0
RIPK1	-11184.0
RASA4	-11187.0
JAG2	-11198.0
TTC21B	-11208.0
SLC24A1	-11214.0
IL5RA	-11247.0
SPDL1	-11264.0
PEBP1	-11270.0
PDE3B	-11323.0
CXCR6	-11329.0
RGS12	-11332.0
RHOC	-11333.0
CXCR3	-11340.0
MXD4	-11361.0
PSMB9	-11362.0
SOX13	-11374.0
LAT	-11376.0
PIP4K2C	-11384.0
DGKE	-11387.0
CNOT6L	-11389.0
ACVR2A	-11411.0
PPP2R5C	-11413.0
GRM2	-11428.0
SPTAN1	-11438.0
NEURL1	-11443.0
PDGFRB	-11452.0
CASP8	-11463.0
CUL1	-11467.0
ATP6V0E2	-11475.0
NCK1	-11488.0
LCK	-11492.0
GPR18	-11501.0
PRKCZ	-11508.0
CDH1	-11512.0
RAG1	-11517.0
ALDH1A1	-11523.0
SMAD3	-11541.0
BUB3	-11546.0
KIF7	-11554.0
RTP4	-11572.0
S1PR2	-11574.0
CMKLR1	-11580.0
PARP1	-11586.0
TRAF2	-11594.0
DUSP8	-11604.0
RPS6KA5	-11616.0
CCNE1	-11655.0
RANGAP1	-11665.0
GPR183	-11676.0
TRAF1	-11688.0
GPR20	-11696.0
P2RY10	-11698.0
CAMK2D	-11728.0
FZD4	-11733.0
NCAM1	-11736.0
TNRC6C	-11737.0
RASA3	-11752.0
FGFR2	-11753.0
FYN	-11758.0
PTGER4	-11767.0
STAT1	-11769.0
TULP3	-11781.0
AGRN	-11794.0
TLE5	-11797.0
ZWILCH	-11800.0
AKT3	-11804.0
CENPL	-11807.0
RASGRP1	-11817.0
FGFRL1	-11838.0
DLL1	-11843.0
DLG3	-11848.0
P2RY14	-11853.0
PRKACB	-11857.0
BCL9L	-11860.0
CENPP	-11863.0
FMNL3	-11869.0
RASAL3	-11874.0
ADRB2	-11879.0
CENPC	-11902.0
PHLPP2	-11904.0
SMAD7	-11905.0
PTCH1	-11908.0
NMT2	-11923.0
SCT	-11927.0
MADD	-11931.0
PRR5	-11948.0
KDM3A	-11950.0
KIF3A	-11957.0
PTGDR	-11967.0
MOV10	-11980.0
IL2RG	-11983.0
CCDC88C	-12005.0
CCL4	-12010.0
ARAP2	-12011.0
PPP3CC	-12030.0
PIK3R3	-12037.0
PRKCQ	-12039.0
RNF43	-12040.0
EVL	-12046.0
ARHGEF3	-12048.0
IL3RA	-12063.0
GPR68	-12068.0
GNGT2	-12070.0
OTUD7B	-12072.0
DHRS3	-12082.0
RBBP7	-12085.0
GIPR	-12098.0
AKR1C3	-12115.0
RALGDS	-12117.0
FPR3	-12129.0
GATA3	-12140.0
YES1	-12143.0
PTGDR2	-12145.0
VIPR2	-12157.0
AMOT	-12161.0
TAGAP	-12171.0
MAGED1	-12172.0
SMPD3	-12182.0
ATP6V0A2	-12193.0
DUSP5	-12201.0
ARHGEF25	-12202.0
NMUR1	-12210.0
MATK	-12213.0
RTKN	-12215.0
FGFBP2	-12222.0
PDGFD	-12226.0
ARHGEF9	-12232.0
C3	-12243.0
ARL4C	-12246.0
PRKCH	-12254.0
LGR6	-12255.0
ARHGAP8	-12256.0
PTPRS	-12262.0
S1PR5	-12275.0
ERBB2	-12281.0
CXCL10	-12284.0
RHOF	-12291.0
AXL	-12293.0
CCL2	-12298.0
IL2RB	-12307.0
GZMB	-12311.0
RUNX3	-12312.0
TFDP2	-12315.0
SH2D2A	-12317.0
FASLG	-12319.0

---

Hemostasis

	496
set	Hemostasis
setSize	550
pANOVA	4.64e-24
s.dist	0.252
p.adjustANOVA	9.04e-22

Top enriched genes

GeneID	Gene Rank
SIRPA	9550
CD177	9539
F12	9535
F5	9524
CYB5R1	9511
GNA15	9499
SERPINB2	9491
NFE2	9490
CD36	9486
MAFG	9463
ITGAM	9453
PRKACA	9441
GNG10	9436
CLU	9423
CD63	9330
GRB2	9320
QSOX1	9302
APLP2	9296
FERMT3	9287
PHF21A	9284

Click HERE to show all gene set members

GeneID	Gene Rank
SIRPA	9550.0
CD177	9539.0
F12	9535.0
F5	9524.0
CYB5R1	9511.0
GNA15	9499.0
SERPINB2	9491.0
NFE2	9490.0
CD36	9486.0
MAFG	9463.0
ITGAM	9453.0
PRKACA	9441.0
GNG10	9436.0
CLU	9423.0
CD63	9330.0
GRB2	9320.0
QSOX1	9302.0
APLP2	9296.0
FERMT3	9287.0
PHF21A	9284.0
ALDOA	9274.0
PLA2G4A	9234.0
MAPK14	9219.0
BSG	9214.0
ACTN1	9210.0
THBD	9202.0
HBD	9189.0
SERPINB8	9181.0
SERPINA1	9179.0
HBE1	9170.0
TNFRSF10D	9167.0
LHFPL2	9147.0
APP	9123.0
SYK	9087.0
RCOR1	9086.0
MAPK3	9078.0
STXBP2	9067.0
PIK3CB	9065.0
GNAQ	9024.0
SELL	9023.0
PRKCD	9012.0
MRVI1	8968.0
ITGA2B	8942.0
CRK	8941.0
TOR4A	8938.0
CLEC1B	8937.0
F13A1	8919.0
ITGB2	8908.0
VTI1B	8892.0
SLC16A3	8884.0
GNG5	8866.0
HGF	8856.0
APBB1IP	8849.0
HBG2	8831.0
ITGA1	8818.0
LAMP2	8803.0
SRGN	8781.0
H3-3A	8754.0
RAC1	8720.0
CDK5	8663.0
PRKAR1A	8616.0
TIMP1	8594.0
CLEC3B	8592.0
TLN1	8554.0
RHOG	8544.0
GATA1	8529.0
HBB	8528.0
CAPZA2	8521.0
ARRB2	8517.0
SELP	8499.0
PLAUR	8490.0
CD99	8467.0
KIF3C	8451.0
P2RX1	8444.0
TNFRSF10B	8435.0
ANXA2	8424.0
SYTL4	8410.0
SLC8A1	8400.0
FGR	8397.0
ITGB3	8367.0
CD44	8314.0
PPP2CA	8308.0
HBG1	8299.0
FN1	8294.0
KIF1B	8290.0
GYPB	8279.0
GNB1	8278.0
EGF	8267.0
CFL1	8242.0
GNB2	8234.0
PRCP	8222.0
RHOA	8218.0
CAP1	8200.0
CAPZA1	8165.0
GAS6	8164.0
LY6G6F	8148.0
KIF5B	8144.0
FCER1G	8143.0
F11R	8139.0
JAML	8137.0
ANXA5	8122.0
GNAI2	8094.0
ORM1	8082.0
ATP2A2	8071.0
CAPZB	8057.0
PRKAR1B	8040.0
GNAI3	8027.0
VAV1	8021.0
GNAS	8019.0
RAF1	7991.0
MERTK	7957.0
GYPA	7935.0
P2RY1	7929.0
SCCPDH	7913.0
CALU	7894.0
DGKG	7861.0
CD99L2	7820.0
KIF1C	7816.0
PPP2CB	7769.0
PROS1	7763.0
MMRN1	7746.0
PECAM1	7743.0
SH2B2	7742.0
MGLL	7741.0
P2RX4	7740.0
DOCK4	7739.0
LYN	7728.0
ITGA5	7699.0
DOCK2	7631.0
GP1BB	7606.0
ESAM	7592.0
GP9	7589.0
SERPINE1	7580.0
ABCC4	7559.0
CDC42	7539.0
MAPK1	7520.0
KLC3	7479.0
TAGLN2	7451.0
STXBP3	7442.0
ITGAX	7429.0
DOCK5	7414.0
DOCK1	7413.0
SPARC	7411.0
TSPAN7	7393.0
VEGFA	7389.0
AKAP10	7388.0
VCL	7380.0
PIK3R6	7359.0
RAP1A	7319.0
MMP1	7209.0
RAB5A	7166.0
GNB4	7138.0
HSPA5	7118.0
GYPC	7084.0
TREM1	7071.0
VEGFC	7057.0
PRKCB	7056.0
WDR1	7052.0
SLC7A7	7038.0
CEACAM1	7034.0
KCNMA1	7008.0
F8	6996.0
CEACAM3	6960.0
PSAP	6909.0
GP6	6890.0
PPP2R5B	6870.0
PRKG1	6867.0
PRKAR2B	6824.0
PRTN3	6822.0
S100A10	6784.0
H3C15	6780.5
ITPK1	6777.0
PDE5A	6774.0
MFN2	6759.0
KCNMB4	6713.0
SDC4	6673.0
CD58	6665.0
SRI	6664.0
GNG11	6612.0
VWF	6607.0
TUBA4A	6587.0
IRF2	6511.0
SERPINE2	6506.0
ATP1B2	6466.0
TMSB4X	6399.0
GTPBP2	6377.0
JAM3	6376.0
GP1BA	6320.0
PRKAR2A	6265.0
PDPK1	6209.0
PTPN6	6176.0
ITGAV	6133.0
EHD2	6129.0
MICAL1	6120.0
ORAI2	6102.0
DOCK8	6088.0
KIF13B	6047.0
PPBP	6029.0
CD9	6004.0
PPP2R5A	5985.0
THBS1	5946.0
ITPR2	5919.0
DAGLB	5909.0
GNA13	5903.0
PDE1B	5822.0
PTPN1	5797.0
SERPINB6	5793.0
PF4	5777.0
YWHAZ	5687.0
A1BG	5617.0
KLC1	5596.0
KIF23	5584.0
HDAC2	5569.0
PFN1	5562.0
PHACTR2	5504.0
PDGFA	5484.0
NRAS	5411.0
PTPN11	5383.0
RAD51B	5364.0
CSK	5285.0
SDC2	5257.0
RAC2	5238.0
ECM1	5213.0
TGFB1	5201.0
SLC3A2	5197.0
KIF20A	5165.0
TBXA2R	5139.0
ACTN4	5132.0
PLCG2	5103.0
PIK3R2	5051.0
P2RY12	5031.0
EHD3	5008.0
OLA1	4999.0
PLAU	4978.0
VAV3	4974.0
CEACAM8	4935.0
F2RL3	4924.0
HMG20B	4906.0
CEACAM6	4720.0
PIK3CA	4697.0
PPP2R1A	4669.0
LRP8	4619.0
SLC16A1	4517.0
PTK2	4506.0
EHD1	4417.0
SELPLG	4369.0
CD109	4343.0
GNG8	4339.0
KIF9	4310.0
SHC1	4173.0
ITGA2	4159.0
STIM1	4011.0
SH2B3	3920.0
DOCK11	3905.0
KIF3B	3773.0
KIF4A	3763.0
KRAS	3760.0
PICK1	3721.0
AKT1	3656.0
RAB27B	3588.0
CD84	3478.0
TIMP3	3463.0
P2RX7	3420.0
ENDOD1	3416.0
GNA12	3399.0
GNAI1	3364.0
KCNMB3	3345.0
ALB	3339.0
PDE11A	3338.0
RAP1B	3331.0
GNA11	3239.0
JMJD1C	3235.0
SLC7A5	3224.0
RACGAP1	2921.0
KIF16B	2817.0
CHID1	2811.0
MPL	2709.0
JAK2	2599.0
ANGPT1	2578.0
KIF27	2576.0
SDC3	2535.0
MANF	2532.0
VPS45	2526.0
DOCK6	2514.0
ADRA2A	2476.0
OLR1	2447.0
PPP2R5D	2440.0
PLEK	2120.0
ARRB1	2098.0
PIK3CG	2046.0
CFD	2016.0
SLC16A8	2015.0
SLC7A8	1948.0
CAV1	1856.0
SLC8A3	1830.0
TNFRSF10A	1785.0
GRB14	1784.0
APOOL	1644.0
CD48	1543.0
NOS1	1401.0
PF4V1	1380.0
GP5	1281.0
TTN	1246.0
RHOB	1190.0
TF	1172.0
PRKCA	1163.0
KIF6	1162.0
KIF11	950.0
MAFK	907.0
GNG3	894.0
KIF2C	812.0
CENPE	741.0
SLC7A9	708.0
IGHV1-2	679.0
STX4	626.0
MYB	555.0
FLNA	547.0
GNB5	467.0
MAFF	434.0
HDAC1	394.0
JAM2	252.0
ABL1	229.0
AK3	176.0
IGHV2-5	174.0
IGHV3-53	122.0
RAPGEF3	25.0
IGLC3	-37.0
ITGB1	-50.0
KIF18B	-123.0
KIFC1	-166.0
IGKV1-39	-173.0
ITGA10	-226.0
PPP2R1B	-246.0
GLG1	-256.0
IGKV5-2	-357.0
P2RX5	-377.0
IGLV5-45	-419.0
IGHV3-7	-437.0
IGKV3-11	-446.0
KCNMB1	-467.0
DGKD	-515.0
IGHV3-48	-583.0
PPP2R5E	-627.0
PDE2A	-735.0
IGLV2-8	-740.0
TMX3	-800.0
IGHV1-46	-823.0
DOK2	-832.0
ATP1B3	-884.0
C1QBP	-902.0
IGKV1-5	-984.0
IGKV1-16	-990.0
ATP2A3	-999.0
IGHV3-23	-1042.0
KIF2A	-1080.0
LCP2	-1167.0
IGKV1D-39	-1172.0
PLAT	-1233.0
VPREB3	-1249.0
IGKV2D-28	-1291.0
IGHA2	-1293.0
IGLV7-46	-1341.0
IGLV10-54	-1414.0
IGHV3-13	-1436.0
IGLV2-18	-1472.0
KIFC2	-1555.0
IGKV1-33	-1613.0
IGLV1-36	-1670.0
NOS3	-1718.0
IGKV2-30	-1725.0
IGLV4-69	-1768.0
IGHA1	-1803.0
IGHV1-69	-1811.0
F2RL2	-1922.0
TRPC6	-1948.0
IGHV4-59	-1969.0
PCYOX1L	-1974.0
PLG	-1998.0
IGLV3-19	-2016.0
IGKV3-15	-2034.0
IGHV3-11	-2041.0
CALM1	-2048.0
IGHV4-34	-2080.0
IGHM	-2111.0
ABHD6	-2164.0
GNG4	-2175.0
IGHV3-30	-2221.0
PIK3R5	-2346.0
DOCK7	-2432.0
ORM2	-2594.0
IGLV2-23	-2597.0
IGKV4-1	-2625.0
SERPIND1	-2671.0
MAGED2	-2729.0
KIF18A	-2744.0
GNB3	-2776.0
IGLV2-11	-2782.0
IGKV1-17	-2799.0
IGKV3-20	-2824.0
TFPI	-2847.0
IGLV6-57	-2876.0
ITIH3	-2982.0
IGHV3-33	-2989.0
IGLV1-44	-3076.0
DGKH	-3171.0
IGHV2-70	-3195.0
KIF15	-3246.0
HRAS	-3335.0
AAMP	-3695.0
IGHV4-39	-3735.0
JCHAIN	-3826.0
MIF	-3828.0
ANGPT2	-3972.0
INPP5D	-3984.0
IGKV3D-20	-4012.0
VAV2	-4073.0
IGLV3-1	-4093.0
IGLV7-43	-4100.0
IGLV1-40	-4105.0
DOCK3	-4198.0
IGKC	-4212.0
IGLV3-25	-4239.0
ANGPT4	-4408.0
IGLV1-51	-4413.0
ATP2A1	-4436.0
IGLV3-21	-4455.0
KIF26A	-4564.0
RBSN	-4574.0
GPC1	-4697.0
ITGA6	-4717.0
IGLC7	-4779.0
P2RX6	-4818.0
SOD1	-4927.0
MFN1	-5002.0
CDK2	-5018.0
GNG7	-5049.0
ATP2B4	-5075.0
GUCY1B2	-5105.0
IGKV1-12	-5223.0
IGLC2	-5370.0
IGLV8-61	-5395.0
CARMIL1	-5405.0
IGLC1	-5548.0
DGKZ	-5636.0
SLC7A11	-5652.0
SOS1	-5714.0
IGKV2-28	-5778.0
IGLV1-47	-5810.0
IGLV3-27	-5935.0
PDE9A	-6171.0
SLC7A6	-6200.0
ITIH4	-6217.0
L1CAM	-6232.0
BRPF3	-6480.0
SERPINF2	-6601.0
KIF28P	-6736.0
KIF21B	-6771.0
PPIA	-6900.0
ORAI1	-7202.0
SELENOP	-7304.0
IGLV3-12	-7472.0
TGFB2	-7546.0
ITPR1	-7553.0
RAD51C	-7586.0
DGKA	-7619.0
TGFB3	-7674.0
GNG2	-7809.0
NHLRC2	-7843.0
VEGFB	-7866.0
KIF20B	-7903.0
PRKCE	-8024.0
RASGRP2	-8137.0
KLC4	-8231.0
CABLES2	-8237.0
DGKQ	-8252.0
KIF5C	-8297.0
SH2B1	-8341.0
KIF5A	-8378.0
CDC37L1	-8413.0
ATP2B1	-8415.0
IGLV2-14	-8416.0
TEX264	-8472.0
PRKG2	-8538.0
IRF1	-8550.0
PDGFB	-8575.0
KLC2	-8724.0
DAGLA	-8730.0
KLKB1	-8735.0
KIFAP3	-8777.0
SRC	-9011.0
ATP1B1	-9055.0
SIRPG	-9138.0
CBX5	-9139.0
GATA2	-9305.0
WEE1	-9320.0
PTGIR	-9321.0
CD244	-9403.0
KDM1A	-9476.0
CABLES1	-9515.0
TRPC3	-9546.0
ZFPM2	-9561.0
PIK3R1	-9725.0
A2M	-9822.0
F2R	-9847.0
ITPR3	-9955.0
PPIL2	-9988.0
FAM3C	-10007.0
PROC	-10273.0
DOCK9	-10312.0
ZFPM1	-10381.0
PLCG1	-10473.0
DGKK	-10512.0
DOCK10	-10544.0
ABHD12	-10579.0
ITGA3	-10589.0
SIN3A	-10648.0
TP53	-10936.0
PROCR	-10957.0
HABP4	-10972.0
ITGA4	-11003.0
ITGAL	-11015.0
AKAP1	-11195.0
CTSW	-11238.0
LAT	-11376.0
DGKE	-11387.0
PPP2R5C	-11413.0
SERPING1	-11444.0
LCK	-11492.0
CD74	-11498.0
PRKCZ	-11508.0
KIF19	-11579.0
LGALS3BP	-11611.0
KIF26B	-11671.0
CD2	-11713.0
FYN	-11758.0
RASGRP1	-11817.0
KIF21A	-11830.0
PRKACB	-11857.0
GATA6	-11955.0
KIF3A	-11957.0
PIK3R3	-12037.0
PRKCQ	-12039.0
GNGT2	-12070.0
CD47	-12112.0
GATA3	-12140.0
YES1	-12143.0
PRKCH	-12254.0
PAFAH2	-12278.0
KIF22	-12286.0
SPN	-12329.0

---

Metabolism

	634
set	Metabolism
setSize	1772
pANOVA	3.22e-22
s.dist	0.139
p.adjustANOVA	5.48e-20

Top enriched genes

GeneID	Gene Rank
PPARG	9571
PLBD1	9569
CYP19A1	9565
CYP1B1	9556
CTSA	9555
NMNAT2	9554
IDH1	9547
PLB1	9542
VCAN	9538
IMPA2	9537
MGST1	9532
PGD	9530
BST1	9529
DSE	9520
KCNG2	9513
TALDO1	9505
GNA15	9499
HSD3B7	9497
GGT1	9495
SLC25A37	9487

Click HERE to show all gene set members

GeneID	Gene Rank
PPARG	9571
PLBD1	9569
CYP19A1	9565
CYP1B1	9556
CTSA	9555
NMNAT2	9554
IDH1	9547
PLB1	9542
VCAN	9538
IMPA2	9537
MGST1	9532
PGD	9530
BST1	9529
DSE	9520
KCNG2	9513
TALDO1	9505
GNA15	9499
HSD3B7	9497
GGT1	9495
SLC25A37	9487
CD36	9486
PLIN3	9485
PYGL	9481
SULT1B1	9479
PGAM1	9478
ACSS2	9465
HADHB	9462
FAH	9456
TNFAIP8L3	9442
PRKACA	9441
ADIPOR1	9439
GNG10	9436
ACOX2	9435
BLVRB	9433
OLAH	9430
HK3	9425
CA1	9414
PGM2	9410
OPLAH	9409
PLCD3	9404
PKM	9395
TSPO	9388
GAPDH	9386
TKT	9382
GPX1	9380
TPST1	9377
CDA	9374
IMPDH1	9364
PCTP	9354
ACSL1	9334
MAOA	9325
PC	9322
PFKFB4	9315
HK2	9313
GNS	9309
LTA4H	9300
ALDH4A1	9293
NMNAT1	9291
AGPAT2	9286
DGAT2	9279
ALDOA	9274
OAZ1	9267
CHP1	9263
ALAS2	9258
GSR	9256
VNN2	9253
PLD1	9245
CES1	9240
PLA2G4A	9234
TK2	9223
BSG	9214
LYVE1	9187
CERS2	9183
ACER3	9166
HYAL2	9156
VNN1	9151
DPYD	9146
SLC2A3	9144
GYG1	9141
SLC6A8	9132
CRLS1	9126
CARM1	9122
INPPL1	9115
MTMR3	9105
AK4	9102
ADCY3	9101
PTGR1	9097
GSTO1	9089
ALOX5	9088
NEU1	9084
ARF1	9083
LRP1	9081
FIG4	9074
VAPA	9073
PIK3CB	9065
GLUL	9061
GK	9053
BCKDK	9049
BPGM	9046
G6PD	9045
GBA	9040
PAPSS1	9039
SGMS2	9038
SBF2	9037
PNPLA2	9033
GNAQ	9024
PISD	9013
HK1	9004
GM2A	9002
PLCB3	8999
PPT1	8997
BMX	8978
SUMF1	8969
ME1	8961
ACOX1	8954
CRAT	8952
SLC19A1	8929
MTF1	8921
CHST15	8916
OAT	8914
GALK1	8913
ITPKC	8910
B4GALT5	8909
ARG1	8895
CYB5R3	8887
SLC16A3	8884
SGMS1	8878
ENO1	8877
HSD17B4	8874
NUP58	8872
CHPT1	8870
GNG5	8866
GCKR	8862
OAZ2	8861
PECR	8860
PFKFB3	8842
AMPD3	8841
PLA2G15	8840
GLCE	8819
SORD	8817
MGST2	8789
PHKB	8783
ST3GAL2	8782
PGS1	8773
ETHE1	8771
FAR2	8769
TCN2	8759
HEXB	8749
LDHA	8743
FAR1	8738
HADHA	8736
ACSL4	8735
GLRX5	8714
NQO2	8711
NUDT16	8696
LPCAT3	8695
ACSS3	8682
PGK1	8681
TBXAS1	8676
ELOVL3	8667
PDXK	8664
GLB1	8652
GDE1	8648
MBOAT7	8643
PUDP	8642
CACNA1E	8640
SMARCD3	8637
UPP1	8634
SERINC2	8629
MAOB	8620
PRKAR1A	8616
ETFA	8614
PHKA2	8608
ALAD	8605
LPCAT2	8600
NT5C2	8598
SLCO2B1	8590
SPTLC1	8570
GMPR	8569
LPGAT1	8562
GNPDA1	8561
POR	8556
MTHFS	8551
FUT7	8545
NDUFB3	8536
PSMB7	8535
PNP	8525
PTEN	8516
SLC44A1	8514
SDHC	8512
PSMD4	8498
PTGS1	8495
ALDH3B1	8489
MBOAT2	8487
GALC	8476
GLTP	8455
CA4	8447
DERA	8442
HPSE	8427
MLX	8423
GPCPD1	8420
TXN	8414
SPTLC2	8413
ACADVL	8405
GLA	8404
ACAA1	8398
SLC27A1	8395
ENTPD1	8372
ASAH1	8368
NDUFB9	8336
PSME3	8331
HNMT	8326
SP1	8315
CD44	8314
PPP2CA	8308
TXNRD1	8303
NDUFAF1	8295
GNB1	8278
AGPAT1	8269
GPAT3	8266
COMT	8260
VDR	8258
PLIN2	8254
HAAO	8241
GBE1	8237
GNB2	8234
LBR	8224
CHSY1	8210
HMGCR	8207
CSGALNACT2	8206
HMOX1	8196
IQGAP1	8189
PSMB5	8188
UQCRH	8187
NDST1	8179
ENTPD7	8174
MTHFD2	8156
SEC24D	8130
ACOT8	8129
DDAH2	8118
HSD17B11	8101
GNAI2	8094
ETFDH	8086
MTMR10	8079
ARNT	8074
ALDH2	8069
ALOX5AP	8054
RAB4A	8050
PRKAR1B	8040
LYPLA1	8039
GAA	8031
GNAS	8019
BCAT1	8018
PCYT1B	8017
SLC9A1	8016
PLPP3	8015
NUP214	8011
MTMR14	7999
GLRX	7985
TBL1X	7984
NDST2	7970
COX15	7963
NCOR2	7948
CRYM	7941
IPMK	7940
ACSL3	7928
SRD5A1	7921
MPST	7905
CHPF2	7903
ABHD5	7892
ALAS1	7891
PSMD6	7881
CERT1	7872
TST	7850
MTMR6	7838
UQCRC1	7829
FADS1	7822
COX7A2L	7808
GLIPR1	7804
TMLHE	7801
ARF3	7798
SEPHS2	7779
NADK	7775
ETFB	7772
PPP2CB	7769
COASY	7767
GMPR2	7766
SLC25A44	7760
ELOVL7	7755
HAL	7750
MGLL	7741
PDSS1	7738
SLC35D2	7734
HPGD	7730
NFYC	7726
SPHK1	7724
PNPLA8	7718
SEC24A	7716
PSMD9	7712
NAMPT	7702
CDK19	7697
ALOX12	7677
SAMD8	7670
SUCLA2	7667
NDUFB1	7664
ATP5PB	7663
ATP5PD	7656
MLXIPL	7653
SULT1A1	7643
PANK2	7626
MED8	7625
HPD	7623
ALOX15B	7608
RGL1	7604
DHRS7B	7583
SDHB	7568
GPD2	7553
CKM	7534
RXRA	7513
NR1H2	7512
NAPRT	7506
NUDT4	7505
PSMD2	7470
GUSB	7454
FDFT1	7450
PLD3	7441
STARD3NL	7438
SEC23A	7416
SLC25A11	7390
ARSB	7373
MANBA	7361
PIK3R6	7359
PSMA1	7346
FBP1	7339
SLC36A4	7336
ABCD1	7330
RAP1A	7319
UGP2	7314
RPL26L1	7295
HSD17B12	7286
PSMD1	7283
SPR	7281
ARSD	7273
PLD2	7268
PSMB3	7265
DLD	7253
AHR	7227
AZIN1	7223
CSAD	7221
GYS1	7212
LRP10	7198
FUT4	7181
ELOVL1	7175
PSMA7	7174
RAB5A	7166
GNB4	7138
COQ2	7116
PSMC1	7096
PPP1CB	7093
NDUFAF3	7092
PCBD1	7091
RAB14	7090
OSBPL8	7064
ABHD3	7047
SDHD	7024
SLC22A5	7020
UQCR11	7005
INPP5A	6989
FECH	6982
ME2	6969
CYP51A1	6941
PSMB6	6927
EXT1	6923
PCYT1A	6918
PSAP	6909
UPB1	6907
DHCR7	6900
PNPLA6	6897
MAN2B1	6854
MED20	6851
RRM2B	6849
TIMMDC1	6842
PTDSS1	6840
VKORC1	6837
HACD4	6831
PRKAR2B	6824
PYCR1	6813
NAT1	6809
GNPAT	6803
SREBF2	6802
IDI1	6791
ITPK1	6777
UBB	6737
TPI1	6730
PSMF1	6724
COX8A	6712
PSMC6	6701
PSAT1	6682
SDC4	6673
ST3GAL6	6671
PDSS2	6660
CDS2	6658
SREBF1	6642
SERINC3	6637
ATP5F1C	6627
ATP5MF	6615
LMBRD1	6613
GNG11	6612
SMS	6602
KYNU	6595
MGST3	6592
NDUFA4	6586
SAR1B	6562
ADI1	6559
ESD	6556
INSIG2	6542
NUDT19	6540
PSMD12	6537
ATP5F1A	6536
CPT2	6535
AOC1	6531
PIP5K1B	6526
ATP5F1B	6524
ABHD4	6523
RUFY1	6499
OSBPL9	6497
ATP5PF	6488
AHCYL1	6475
SMOX	6454
HPRT1	6452
SAMHD1	6437
OCRL	6436
MMADHC	6435
CSNK2A2	6430
PSPH	6409
LRP12	6407
CHST13	6406
CMBL	6405
ISCA1	6388
DBI	6372
CBS	6363
RDH11	6355
NDUFS1	6345
PPP1CC	6334
CYP4F3	6333
LDLR	6329
COX5B	6328
CES2	6323
SYNJ1	6310
CDIPT	6305
PSMD11	6296
UQCRFS1	6294
MED25	6290
DEGS1	6287
TCN1	6281
AOC2	6279
PRKAR2A	6265
ATP5F1E	6259
NDUFS5	6252
GPI	6246
COX5A	6238
PPCS	6216
MTM1	6213
EP300	6208
CSNK2A1	6207
NDUFC2	6199
PIP5K1A	6198
PPIP5K2	6178
EHHADH	6173
NDUFS2	6169
DNM2	6163
PGLS	6161
BCKDHA	6138
FABP5	6123
MED13L	6114
NDUFA6	6108
CHKA	6099
PIK3CD	6096
ELOVL5	6074
ORMDL2	6068
ABCA1	6066
NT5M	6065
PFKFB2	6061
ACOX3	6059
SUCLG1	6053
PSMD7	6017
ATP5MC3	6010
GDPD3	5993
PSMD13	5991
B3GNT2	5988
SGSH	5984
NCOR1	5979
PSMA6	5978
ESRRA	5973
CPNE3	5955
PGM1	5947
ST3GAL4	5930
ITPR2	5919
PHYKPL	5913
ASL	5910
HMBS	5908
NDUFB10	5889
UQCRC2	5885
PTDSS2	5876
ISCA2	5875
TPST2	5872
PDK4	5854
PITPNM1	5849
NDUFAB1	5846
PSMD8	5845
NCOA6	5838
AFMID	5835
NDUFA1	5827
SEC13	5820
SERINC1	5810
ABCC3	5806
RHCE	5803
CERS6	5802
APOA2	5784
BLVRA	5778
PLA2G12A	5774
PLAAT1	5768
COX6B1	5755
COQ5	5730
TNFAIP8L2	5726
ARG2	5708
NUDT3	5705
NDUFA7	5698
B3GALNT1	5686
DHTKD1	5669
G6PC	5665
ADPGK	5648
SLC35B3	5625
SYT5	5610
ATP5MG	5608
STAB2	5599
ACAT1	5575
GCLM	5558
GLUD1	5549
ACSM2A	5541
PTGES	5538
MCAT	5524
SULT1A4	5512
GUK1	5507
RPS9	5496
ACOT13	5491
MBOAT1	5488
GCHFR	5478
B3GALT4	5470
SUOX	5466
GSTZ1	5456
AMPD2	5453
NDUFC1	5436
PSMA2	5433
FDPS	5431
AGPS	5430
RIDA	5404
ACACA	5394
CYP2C9	5390
HMGCL	5372
DGAT1	5367
TKFC	5347
ALDH1L2	5326
G0S2	5324
MED16	5319
SAT1	5294
NUDT9	5282
DECR1	5280
ACOT9	5268
DHFR	5266
SDC2	5257
PIAS4	5248
HYAL3	5235
ADCY4	5226
NFS1	5225
NME4	5221
ACLY	5214
GPX4	5204
SLC3A2	5197
NDUFV3	5191
OSBPL2	5188
COX6A1	5167
CPT1A	5153
RAE1	5152
HAGH	5151
ADSL	5147
GALE	5138
PLCG2	5103
MTHFR	5087
ASRGL1	5085
APIP	5064
SUMO2	5062
PIK3R2	5051
CRYL1	5050
SLC25A1	5044
UROD	5038
NDUFA2	5018
ECSIT	4997
ADIPOR2	4989
FUT1	4948
UCK1	4901
ACAD10	4889
NDUFA8	4885
ATP5PO	4868
CHST11	4863
STARD10	4820
ACOXL	4818
FDXR	4803
TK1	4778
SLC22A1	4772
COQ7	4770
HDAC3	4734
TXN2	4728
PIK3CA	4697
PLCB2	4696
PSMD3	4693
HSD17B13	4686
KYAT3	4676
NSDHL	4673
PPP2R1A	4669
MPC2	4629
TBL1XR1	4627
AGPAT3	4625
HS6ST1	4620
LRP8	4619
SPTSSA	4614
NDUFB4	4594
FHL2	4582
HACD1	4576
NUBP1	4572
NCOA1	4563
COX7B	4554
NUP50	4544
RPL3L	4539
SLC16A1	4517
MED18	4492
SCP2	4477
NT5C3A	4476
TACO1	4468
MED26	4456
OSBPL6	4454
NNT	4452
SEM1	4436
UQCR10	4424
UBC	4421
TPMT	4406
PTGS2	4402
ACADS	4365
B4GALT1	4354
NDUFV2	4345
PDHX	4344
GNG8	4339
VKORC1L1	4337
MAN2B2	4317
SQLE	4315
VDAC1	4300
PARP4	4298
HYAL1	4297
NDUFA13	4294
PDHB	4292
HSD17B10	4284
GLYAT	4281
HSD17B2	4277
PDK1	4269
MDH2	4266
NDUFB6	4265
GPT2	4261
NDUFS6	4258
COX4I1	4252
STS	4231
ACO2	4228
GPAT4	4202
PTGES3	4180
MAPKAPK2	4176
PLA2R1	4167
GSTM5	4166
PPP1CA	4156
CSGALNACT1	4139
OGDH	4138
SCD	4108
PSMB2	4103
UGDH	4095
SULT1A3	4094
SRD5A3	4089
COQ10B	4065
IP6K1	4063
HMMR	4051
SLC25A20	4046
NDUFS4	4035
ALDH6A1	4034
CSNK2B	3987
FABP2	3977
NDUFB5	3970
G6PC3	3956
PPARGC1A	3934
UQCRB	3916
AOC3	3914
CYP27A1	3913
ACSM6	3895
MMUT	3861
HSD11B2	3843
RNLS	3754
MID1IP1	3751
MED22	3738
HS2ST1	3730
CPTP	3715
CS	3685
AKT1	3656
SEC24B	3655
HSD17B1	3651
LIPH	3648
AMD1	3646
IMPAD1	3618
PRPS2	3597
NUDT18	3596
SURF1	3585
RHD	3580
CA2	3565
NCOA3	3563
MTHFD2L	3552
ERCC2	3545
ACAA2	3544
CACNA1D	3525
PXMP2	3517
PSMD5	3507
NFYA	3506
ARSA	3499
CREBBP	3460
STARD7	3453
RFK	3438
PIP5K1C	3436
NADSYN1	3429
PSMB1	3422
SGPL1	3401
PGM2L1	3400
MOCOS	3392
PMVK	3382
GNAI1	3364
SLC6A12	3361
IDH3G	3353
ACBD7	3347
TPH2	3344
ODC1	3342
ALB	3339
AKR1B15	3330
STARD3	3311
PDK3	3304
MED19	3287
MED4	3271
IPPK	3263
PHGDH	3250
GNA11	3239
PIKFYVE	3232
SLC7A5	3224
TMEM86B	3157
NUP37	3153
CYC1	3139
PEMT	3135
NUP98	3124
NAGS	3088
GLB1L	3043
PANK3	3032
GBA2	3025
HSCB	3020
ATP5MC2	3017
MED17	3008
ATP5F1D	3007
MTMR4	2986
UQCRQ	2981
ALDH9A1	2975
POMC	2971
PHOSPHO1	2963
MBTPS1	2958
FH	2955
DGUOK	2916
SPHK2	2863
LPL	2853
DHCR24	2834
KCNB1	2797
TAZ	2765
TYMP	2748
SLC44A2	2733
ABO	2717
PSMD14	2703
PSMC2	2696
NDUFAF7	2695
ATP5ME	2673
RPE	2661
AKR7A2	2604
MSMO1	2601
PLCH1	2577
MED13	2566
PSMB4	2552
SDC3	2535
ABCC5	2534
KPNB1	2491
NDOR1	2489
ADRA2A	2476
AK2	2459
PPP2R5D	2440
PLPP2	2398
CTPS2	2386
SLC37A2	2343
SMPD2	2340
NDUFB7	2332
TTPA	2316
UGCG	2292
PTPMT1	2290
STK11	2241
INMT	2230
VAPB	2225
GCAT	2215
PPA2	2208
CIAO2B	2207
SDSL	2189
NDUFAF2	2174
NDUFS7	2129
RPS27L	2117
ACER2	2079
CBR1	2072
GNMT	2048
PIK3CG	2046
MED12	2042
SPTLC3	2027
MDH1	2019
PSMC3	2018
SLC16A8	2015
MTRR	2007
ENPP2	1990
PPA1	1957
PRKAG2	1942
FDX1	1928
GDA	1925
CCNC	1883
CAV1	1856
NME2	1853
SLC25A19	1765
NME1	1761
SLC46A1	1752
PIK3C2G	1751
UGT1A1	1739
FADS2	1658
PHKG2	1653
PSMD10	1646
PIK3C3	1626
MTMR9	1492
MED31	1486
AKR1A1	1481
NDUFA11	1471
RPIA	1455
HS3ST2	1429
CYP3A43	1403
TECRL	1389
HSP90AA1	1348
PTGR2	1319
HEXA	1274
CA13	1248
GCK	1242
GSTM4	1226
PLCB1	1225
LRP2	1222
NDUFB11	1201
HTD2	1195
CHST14	1177
PRKCA	1163
CEPT1	1134
PLA2G2D	1125
PRKD3	1115
DARS1	1111
NCOA2	1109
SMPD1	1095
ALDH7A1	1087
B4GALNT2	1082
PLA2G4D	1074
UBA52	1071
NUDT7	1055
GRHPR	1018
FMOD	991
NDUFB8	974
UCP2	969
DECR2	957
NDUFS3	929
CSNK1G2	899
GNG3	894
ALDH3A2	887
NPAS2	873
PPARA	865
PLEKHA4	836
MT-ND4	830
NUP62	772
COX6C	721
GSS	697
MT-CO1	675
ABCC1	589
B4GALT4	587
TRMT112	586
COX7C	558
GLDC	544
NDUFA3	528
ECI1	512
TYMS	495
RETSAT	493
ST3GAL3	485
PYGB	484
GNB5	467
MT-ND6	453
PGP	450
AHCY	449
ASPA	441
APOM	422
MTHFD1L	403
THRAP3	398
SLC25A16	363
CACNB3	359
ADH1B	348
AACS	344
WASL	283
AKR1C1	280
AK9	264
SLC25A21	233
COX16	214
FAHD1	203
GSTP1	197
PANK1	190
MED7	178
ADCY9	146
POLD1	133
TPO	132
QARS1	118
APOE	103
RPL36AL	91
NDUFS8	80
MBTPS2	77
ABCG2	62
MT-CO3	47
MT-CO2	35
RAPGEF3	25
AANAT	16
CYP1A2	7
LHPP	-2
ENPP6	-15
FAM120B	-24
RPLP1	-65
VAC14	-91
GADL1	-137
RRM2	-188
LCLAT1	-198
MED14	-205
RPS4Y1	-222
PPP2R1B	-246
PPCDC	-278
RPS24	-282
HGD	-301
IYD	-307
DCXR	-311
CYP46A1	-326
FMO3	-352
LTC4S	-354
ACSF3	-368
GSTM1	-381
FAU	-402
SLC25A13	-413
AASDHPPT	-463
GRHL1	-470
ACADL	-490
TNFAIP8	-517
PSMA4	-538
PCK2	-593
CPOX	-654
GGT5	-679
NME3	-686
IMPA1	-696
SHMT1	-700
FASN	-702
MED11	-713
ACOT11	-716
UBE2I	-746
RANBP2	-808
SLC27A3	-819
MED6	-888
ACAD9	-904
AIMP2	-907
GPS2	-914
MPC1	-945
PSMC5	-948
PLAAT2	-983
PFKM	-988
GGPS1	-996
PNMT	-1013
RPL15	-1017
CYP4F8	-1028
RPLP0	-1054
MINPP1	-1104
SULT1C2	-1115
BPNT1	-1152
AUH	-1200
AKR7L	-1203
SERINC4	-1208
RPL8	-1242
CBR4	-1253
ACBD5	-1261
ACSBG1	-1271
CYCS	-1282
ACADM	-1308
CHST5	-1371
STAR	-1393
MED28	-1397
MOGAT3	-1409
PLEKHA2	-1411
ETNK1	-1416
EXT2	-1435
RPS26	-1443
INPP1	-1453
RPL28	-1469
COX14	-1508
CMPK1	-1520
IDH3B	-1521
HILPDA	-1540
DSEL	-1581
MTMR12	-1597
GSTK1	-1606
MARCKS	-1616
MIOX	-1635
RPL22L1	-1643
GSTM3	-1703
NOS3	-1718
HACD2	-1729
PLEKHA6	-1731
PRELP	-1742
DCTPP1	-1744
ADCY6	-1746
RPS13	-1759
NDUFA12	-1763
NUDT12	-1772
SLC10A1	-1779
ADO	-1810
CHDH	-1825
RPL9	-1827
ABCB7	-1851
ACP5	-1859
B3GAT2	-1861
ISCU	-1869
SLC19A3	-1890
RIMKLA	-1934
PTS	-1979
ABCC2	-1990
CDK8	-1997
HMGCS1	-2006
RPL7	-2018
INPP5K	-2022
CALM1	-2048
PAPSS2	-2099
MT-ATP6	-2106
RPS8	-2138
EEF1E1	-2141
GNG4	-2175
OXCT2	-2179
DHFR2	-2185
MT-ND5	-2218
ADK	-2234
CERS5	-2238
AMDHD1	-2241
MTMR2	-2283
MFSD2A	-2291
NDUFAF6	-2303
ECHS1	-2312
MT-CYB	-2314
PIP4K2A	-2339
PIK3R5	-2346
ACMSD	-2406
PYCR2	-2429
ACSM2B	-2439
CA6	-2450
GCDH	-2451
ALDOB	-2466
LDHAL6A	-2544
SHPK	-2583
MARS1	-2590
CYP4F12	-2606
IDS	-2609
SEC24C	-2615
PI4KA	-2619
NMNAT3	-2646
OSBP	-2661
SLC25A28	-2725
ARV1	-2728
DPEP2	-2760
APRT	-2769
GNB3	-2776
PLA2G4C	-2813
DNPH1	-2837
HIBCH	-2851
ADCY2	-2874
SLC26A2	-2930
RPL27	-2934
NUDT15	-2942
IDH2	-2943
MT-ATP8	-2961
DPEP3	-2980
DIO1	-2988
B3GAT3	-3020
STARD5	-3034
BCAT2	-3036
AK6	-3045
RPL39	-3047
PLEKHA8	-3069
NUP85	-3077
PSMB8	-3080
RBKS	-3109
PPM1L	-3124
CPS1	-3135
NQO1	-3150
ACOT7	-3163
AGL	-3177
PHYH	-3203
GSTO2	-3204
EPRS1	-3205
RXRB	-3221
SLC23A2	-3238
CHKB	-3255
SRR	-3270
PFKL	-3284
TPK1	-3291
CACNA1A	-3294
ADCY7	-3307
NAXE	-3324
ALDOC	-3343
RPL23	-3352
CYP24A1	-3354
PNPLA4	-3380
RPL6	-3382
NUDT1	-3395
CYP27B1	-3407
PITPNM3	-3415
NR1H3	-3418
CPNE1	-3422
CDS1	-3424
MTMR1	-3436
RPL13	-3461
CERS3	-3472
NUDT5	-3484
HYKK	-3487
ISYNA1	-3489
ANGPTL4	-3500
NAALAD2	-3502
THTPA	-3504
PLIN1	-3507
SLC44A5	-3526
PFKP	-3533
GPX2	-3560
OSBPL10	-3564
DLAT	-3566
NMRK1	-3579
MTMR7	-3581
SC5D	-3584
RPL4	-3592
RPL29	-3604
GART	-3611
GPC2	-3613
AIP	-3644
FA2H	-3657
AMN	-3675
ACAT2	-3679
SERINC5	-3684
SLC27A5	-3685
MT-ND3	-3687
MT-ND1	-3693
RPS15	-3698
RPL7A	-3699
PYGM	-3716
CYP2S1	-3718
CYP3A5	-3727
GLO1	-3779
PLD6	-3782
NEU3	-3800
ACP6	-3830
PLA2G10	-3844
MAN2C1	-3895
SLC27A2	-3903
SULT1A2	-3920
GLYCTK	-3948
INPP5D	-3984
RPL37A	-4004
B3GNT3	-4021
KYAT1	-4024
PIK3R4	-4040
B3GALT2	-4053
KCNJ11	-4054
STX1A	-4061
STARD4	-4062
MED1	-4082
SCAP	-4090
RPS21	-4115
SLC19A2	-4125
B3GALT1	-4146
MAT2A	-4193
SIN3B	-4201
KDSR	-4208
DDO	-4221
SCO2	-4299
PDP1	-4302
HS3ST1	-4304
CYP7B1	-4321
SLC23A1	-4333
ACBD4	-4363
CHST6	-4380
SLC25A27	-4389
OAZ3	-4391
NDUFB2	-4470
PDHA1	-4484
PI4KB	-4503
RTEL1	-4505
RPL31	-4507
RPS2	-4509
CSPG4	-4511
ACAD8	-4518
CHD9	-4532
B3GALT6	-4549
CPT1B	-4560
RPS16	-4570
GDPD1	-4597
FAAH2	-4612
RPL5	-4631
ACY1	-4646
RPS28	-4647
PARP9	-4658
ACOT1	-4667
SLC25A14	-4687
GPC1	-4697
RPS3A	-4702
GPC4	-4718
LGMN	-4724
ENTPD6	-4725
NDUFA5	-4736
RPL22	-4738
MCEE	-4753
XYLT2	-4781
CNDP2	-4788
ARSG	-4809
RARS1	-4820
SLC25A12	-4821
NAGLU	-4826
FDX2	-4838
CIAO3	-4845
PITPNM2	-4859
INPP5F	-4892
GLYATL2	-4924
NT5E	-4939
PARP6	-4956
SHMT2	-4965
QDPR	-4988
RPS7	-5016
PLEKHA5	-5028
GPAT2	-5033
COX20	-5036
GNG7	-5049
RPL18	-5054
ABCB4	-5056
ADHFE1	-5066
PPARGC1B	-5117
PLEKHA3	-5120
CERS4	-5145
UGT8	-5170
PAICS	-5171
SLC52A2	-5185
PIK3C2A	-5233
FAAH	-5249
PLPP1	-5262
AGMAT	-5284
RPL36	-5287
CERK	-5289
PSMA3	-5314
SLC5A5	-5315
PRXL2B	-5372
CA14	-5387
FOLR2	-5394
KARS1	-5423
SLC5A6	-5458
RPL17	-5464
GMPS	-5476
RPS5	-5478
RPS14	-5485
TGS1	-5487
NUDT13	-5490
LPIN3	-5491
SDHA	-5523
MED30	-5533
CYB5A	-5537
DBT	-5570
FUT10	-5574
HSD17B3	-5596
DHODH	-5598
ARSJ	-5603
NHLRC1	-5613
NUP42	-5622
MED21	-5663
MRI1	-5664
RPS10	-5686
B4GAT1	-5693
RPS15A	-5695
D2HGDH	-5708
ACSL6	-5710
MIGA2	-5745
ELOVL4	-5763
PSMB10	-5768
MTAP	-5771
IDUA	-5812
IDO2	-5818
OSBPL1A	-5827
RPS3	-5833
AIMP1	-5849
FITM2	-5856
SUCLG2	-5863
RPL24	-5882
SLC37A1	-5886
UCKL1	-5887
RPL38	-5890
TRIB3	-5896
AHRR	-5913
MVD	-5926
CHAC2	-5930
COX10	-5946
SEH1L	-5957
SARS1	-5960
CKMT2	-5968
RPS4X	-5969
RPS12	-5985
ORMDL1	-5997
RPL18A	-6029
LIAS	-6040
STXBP1	-6049
DUT	-6053
RPL35A	-6080
CACNB2	-6089
PPARD	-6092
LYRM4	-6098
PSME4	-6099
RPS6	-6100
SLC37A4	-6111
B4GALT2	-6126
COX18	-6129
PSMA5	-6154
AKR1C2	-6176
FTCD	-6180
ENTPD4	-6182
PON2	-6202
ZDHHC21	-6207
HAS3	-6214
FITM1	-6216
RPSA	-6219
RPS17	-6223
RPL19	-6242
RPS25	-6246
ENTPD5	-6256
RPL11	-6275
RPS23	-6279
LARS1	-6282
RPL27A	-6321
NUP153	-6325
PDZD11	-6343
CYP2J2	-6350
NOSIP	-6387
PNPLA7	-6399
RPL37	-6401
SDS	-6408
AMT	-6422
GGCT	-6478
RPL21	-6481
PNPO	-6484
RPL14	-6518
ALOX12B	-6526
RPL10	-6562
RPL32	-6577
ABHD10	-6625
RPL26	-6636
RPL10A	-6644
PLA2G4B	-6650
MT-ND2	-6660
PI4K2A	-6675
KMO	-6677
PLCE1	-6680
MMACHC	-6681
PLAAT3	-6689
MED23	-6699
HSP90AB1	-6702
CUBN	-6752
MOCS3	-6770
GAMT	-6775
PTGES2	-6796
RPL34	-6807
SLC35D1	-6818
SLC52A1	-6857
GATM	-6862
RAN	-6874
RPL41	-6877
ENO3	-6884
RPS27A	-6894
ARNTL	-6899
INPP5B	-6905
PIPOX	-6907
RPLP2	-6915
COX19	-6928
GPD1	-6946
LPIN2	-6965
AS3MT	-6992
RPL30	-6995
NMRAL1	-7017
NDUFA10	-7022
CPNE7	-7027
RPS19	-7037
RPL12	-7038
AMACR	-7084
TPR	-7100
SRM	-7115
RPS11	-7122
PITPNB	-7128
TM7SF2	-7146
KHK	-7171
GPHN	-7172
CEMIP	-7233
NADK2	-7253
LIPT2	-7266
POM121C	-7305
MECR	-7352
B4GALT7	-7370
DMAC2L	-7416
MIGA1	-7418
PDPR	-7428
RPL36A	-7442
UGT2B11	-7447
ST3GAL1	-7452
CLOCK	-7458
MED24	-7462
ACSM3	-7466
MOCS1	-7491
XYLT1	-7512
ACY3	-7522
ITPR1	-7553
LPCAT1	-7557
PSMA8	-7559
GCH1	-7571
GLS2	-7572
ATP5MC1	-7598
HDC	-7629
INPP5E	-7633
RPS18	-7641
NAXD	-7643
HSPG2	-7708
PIP4K2B	-7720
RPS29	-7794
GNG2	-7809
SULT2B1	-7824
MMS19	-7830
THEM5	-7835
NUP133	-7839
ACER1	-7840
SCD5	-7947
GGT7	-7985
CIAPIN1	-8033
MED29	-8038
PCCB	-8040
TSTD1	-8063
PRKAB2	-8083
CTH	-8093
HS3ST3A1	-8108
PDK2	-8114
RPL13A	-8123
SLC26A1	-8131
SCLY	-8157
ADH5	-8176
CYP2D6	-8194
NT5C1B	-8207
ENO2	-8221
LPCAT4	-8224
RPL35	-8239
CBR3	-8246
COQ9	-8260
POM121	-8263
NRF1	-8292
ASNS	-8299
FLVCR1	-8309
ADCY5	-8315
GCSH	-8329
AAAS	-8337
GNPDA2	-8371
INPP4B	-8398
PARP10	-8407
TMEM126B	-8426
MVK	-8435
ABCD4	-8442
RPL3	-8478
ITPA	-8488
PFKFB1	-8491
FLAD1	-8494
HIBADH	-8514
NUP54	-8521
PANK4	-8522
PARP8	-8523
SYNJ2	-8530
PRKG2	-8538
AGPAT4	-8554
HS3ST3B1	-8560
GSTA4	-8576
PHKG1	-8579
GPT	-8586
NR1D1	-8603
SLC25A15	-8655
MED10	-8659
DCK	-8661
SARDH	-8766
TPH1	-8787
ADPRM	-8788
DBH	-8801
PCCA	-8821
PRKD2	-8832
PLCD1	-8843
BPHL	-8856
BCO2	-8895
GALT	-8914
RPS20	-8922
PODXL2	-8933
CHST7	-8942
NDUFA9	-8944
MED9	-8957
LIPE	-8958
SPTSSB	-8961
B4GALT6	-8981
RPL39L	-8982
AK1	-8989
PEX11A	-9013
MORC2	-9057
DLST	-9072
CYSLTR2	-9085
CES3	-9086
MMAB	-9123
CYP2A6	-9144
MCCC1	-9147
ASAH2	-9155
HSD17B7	-9238
PRODH	-9254
CAD	-9276
CYP2E1	-9284
ETNK2	-9291
NUBP2	-9303
MOCS2	-9304
PSMC4	-9306
HELZ2	-9313
MED27	-9333
SACM1L	-9356
NT5C	-9363
SLC25A32	-9407
IDH3A	-9425
TECR	-9443
RPL23A	-9477
CYP4V2	-9514
DTYMK	-9563
SGPP2	-9574
CD320	-9575
NUP43	-9595
IMPDH2	-9608
GSTM2	-9630
COQ3	-9632
RPS27	-9651
ENPP1	-9686
FUT2	-9708
NDUFAF5	-9710
AASS	-9711
LDHB	-9712
PIK3R1	-9725
ACSM1	-9738
AGPAT5	-9755
INPP4A	-9767
MLYCD	-9783
GOT2	-9837
ACACB	-9846
EPHX1	-9848
EPHX2	-9860
SCO1	-9862
IDO1	-9887
NDUFAF4	-9891
ABHD14B	-9915
MTMR8	-9937
ITPR3	-9955
NFYB	-9957
MED15	-9976
AK5	-9977
GPAM	-9993
ORMDL3	-9994
CYP2R1	-10045
TNFAIP8L1	-10058
CTPS1	-10065
L2HGDH	-10075
PM20D1	-10109
LRPPRC	-10120
ME3	-10128
PSME1	-10138
PTPN13	-10143
SLC35B2	-10159
CIAO1	-10167
PSTK	-10177
NUP35	-10206
ACOT2	-10226
EEFSEC	-10237
DCTD	-10247
IP6K2	-10258
UCP3	-10264
IL4I1	-10288
NUP155	-10291
ACAD11	-10314
UCK2	-10323
UBIAD1	-10333
SLC25A10	-10337
XYLB	-10367
B3GNT4	-10382
NUP160	-10383
PLPP6	-10392
PIK3C2B	-10393
FABP3	-10400
PSME2	-10415
UMPS	-10421
BDH1	-10426
ENOPH1	-10451
ALOX15	-10452
PLCG1	-10473
SECISBP2	-10495
ACADSB	-10504
HSD17B8	-10518
LSS	-10526
SBF1	-10529
MAT2B	-10550
CHPF	-10551
INSIG1	-10566
NUP107	-10570
GDPD5	-10605
B4GALT3	-10619
ENPP3	-10621
GPD1L	-10644
SIN3A	-10648
FPGS	-10655
PFAS	-10664
CARNS1	-10676
N6AMT1	-10679
ACSL5	-10681
PRSS1	-10684
RIMKLB	-10689
EPM2A	-10694
CARNMT1	-10706
CACNA1C	-10711
SLC25A17	-10715
NUP210	-10725
PPIP5K1	-10752
PAOX	-10769
HACD3	-10793
TRAP1	-10800
B3GAT1	-10860
ACOT4	-10881
SELENOI	-10887
PPAT	-10895
CA5B	-10912
PTGDS	-10915
DUOX1	-10924
THEM4	-10987
ACBD6	-11027
NUDT11	-11033
ALDH1B1	-11037
NUP88	-11046
AZIN2	-11076
ALDH18A1	-11080
COX11	-11085
ATIC	-11093
PPT2	-11127
TIAM2	-11149
PDP2	-11174
PLCD4	-11178
BCKDHB	-11180
COQ10A	-11185
PPOX	-11196
DEGS2	-11200
ARSK	-11217
NUP205	-11250
RRM1	-11255
BDH2	-11263
CHST2	-11278
CTRC	-11287
PCYT2	-11296
SLC2A1	-11299
LIPT1	-11305
ITPKB	-11310
HADH	-11322
FXN	-11324
ADAL	-11351
LPIN1	-11358
PSMB9	-11362
CYB5B	-11363
MTHFD1	-11371
PIP4K2C	-11384
SEPSECS	-11393
ACSF2	-11403
NDUFV1	-11489
OXCT1	-11518
ALDH1A1	-11523
NUP188	-11545
DDHD1	-11559
MMAA	-11577
PARP16	-11583
ELOVL6	-11588
NUBPL	-11590
UROS	-11615
UST	-11630
DDHD2	-11651
OSBPL7	-11654
ESYT2	-11669
GLS	-11674
TSPOAP1	-11680
VAMP2	-11692
NUP93	-11700
COQ6	-11711
BRIP1	-11720
GOT1	-11739
IARS1	-11740
SMPD4	-11741
AKR1B1	-11747
HLCS	-11768
GCLC	-11771
HACL1	-11772
HMOX2	-11783
AGRN	-11794
ECI2	-11802
PLCH2	-11820
CACNA2D2	-11825
MCCC2	-11850
PPM1K	-11856
PRKACB	-11857
RORA	-11872
MTR	-11878
OSBPL3	-11889
PARP14	-11897
CROT	-11919
ACSS1	-11942
ST6GALNAC6	-11958
CKB	-11981
CYP2U1	-11986
PRPS1	-11989
CD38	-12001
PLA2G6	-12020
PI4K2B	-12022
NAT8L	-12029
PLEKHA1	-12032
PIK3R3	-12037
QPRT	-12041
AGK	-12045
EBP	-12055
SUMF2	-12066
GNGT2	-12070
BTD	-12100
ESYT1	-12107
NDC1	-12113
AKR1C3	-12115
PLAAT4	-12168
OSBPL5	-12179
FUT11	-12181
SMPD3	-12182
ABCB1	-12187
SGPP1	-12194
IVD	-12218
TNFRSF21	-12219
CYP4F22	-12245
ADA	-12258
B3GNT7	-12264
AKAP5	-12288
PLD4	-12302
CHST12	-12325

---

Signaling by Receptor Tyrosine Kinases

	1131
set	Signaling by Receptor Tyrosine Kinases
setSize	414
pANOVA	1.08e-20
s.dist	0.267
p.adjustANOVA	1.63e-18

Top enriched genes

GeneID	Gene Rank
WASF1	9568
GRB10	9508
ATP6V0A1	9483
LAMC1	9473
PRKACA	9441
MMP9	9370
NCF4	9365
DUSP3	9324
GRB2	9320
ATP6V1A	9301
ATP6V0D1	9298
FES	9280
CYFIP1	9270
TNS3	9238
CTNNA1	9237
MAPK14	9219
NCF2	9209
RIT1	9174
FURIN	9162
NCSTN	9139

Click HERE to show all gene set members

GeneID	Gene Rank
WASF1	9568
GRB10	9508
ATP6V0A1	9483
LAMC1	9473
PRKACA	9441
MMP9	9370
NCF4	9365
DUSP3	9324
GRB2	9320
ATP6V1A	9301
ATP6V0D1	9298
FES	9280
CYFIP1	9270
TNS3	9238
CTNNA1	9237
MAPK14	9219
NCF2	9209
RIT1	9174
FURIN	9162
NCSTN	9139
ATP6V1D	9118
ATP6V0C	9113
MAPK3	9078
DLG4	9070
PIK3CB	9065
CLTC	9056
TGFA	9031
KL	9019
PRKCD	9012
ATP6V1B2	9005
CYBB	9000
MAP2K1	8960
CRK	8941
FOSL1	8911
HGF	8856
MEMO1	8843
PCSK6	8824
RAC1	8720
ADAM10	8705
ATP6V0B	8701
CDH5	8691
AP2M1	8673
CDK5	8663
ATP6V0E1	8662
SOCS6	8639
ATP6V1C1	8628
RALB	8475
RNF41	8473
SPINT1	8470
CLTA	8402
WASF2	8373
ITGB3	8367
IRS2	8323
LYL1	8321
PPP2CA	8308
EGF	8267
MAPKAPK3	8255
PAK1	8252
MKNK1	8248
PAK2	8226
RHOA	8218
SPINT2	8213
STAT3	8152
PTPN12	8125
ATP6V1H	8119
ATP6V1E1	8107
INSR	8103
GAB2	8100
AP2S1	8080
RAB4A	8050
ATP6AP1	8035
MEF2A	8030
EPN1	8026
VAV1	8021
PTK2B	8010
ADAM17	7980
PSEN1	7843
PTPRJ	7833
RPS6KA1	7800
PPP2CB	7769
SH2B2	7742
SH3GL1	7733
LYN	7728
TRIB1	7725
SPHK1	7724
LAMB3	7685
POLR2E	7660
ADAP1	7645
PTPN2	7634
CBL	7599
NCKAP1	7562
CDC42	7539
MAPK1	7520
NCKAP1L	7516
TEC	7488
ROCK1	7445
NCF1	7433
DOCK1	7413
SPARC	7411
FRS3	7402
VEGFA	7389
AP2A2	7360
RAP1A	7319
TCIRG1	7266
FLT3	7222
SRF	7205
DNM3	7167
ABI1	7154
THBS3	7134
KIDINS220	7111
BRK1	7085
TAB2	7070
VEGFC	7057
PRKCB	7056
STAT5B	7011
STAT5A	6983
CYBA	6952
SPRED2	6917
WASF3	6915
MAP2K2	6906
FLT1	6901
JUNB	6889
GFAP	6771
POLR2J	6769
UBB	6737
AP2A1	6628
AHCYL1	6475
CTNNB1	6463
YWHAB	6398
USP8	6383
PXN	6332
NEDD4	6330
ELMO1	6324
APH1B	6248
SH3KBP1	6227
PDPK1	6209
EP300	6208
STAM2	6183
SHB	6181
FOS	6179
PTPN6	6176
DNM2	6163
ROCK2	6151
ITGAV	6133
PDGFC	6090
IGF1R	6032
PDGFRA	6002
PTK6	5998
BAX	5996
NCOR1	5979
STAT6	5950
ATP6V1F	5949
LAMB1	5948
THBS1	5946
PTPN18	5944
ITPR2	5919
RANBP9	5914
PSENEN	5833
PTPN1	5797
ATF1	5790
ATP6V1E2	5776
GAB1	5723
GTF2F2	5503
AREG	5494
PDGFA	5484
NRAS	5411
PTPN11	5383
POLR2L	5362
CSK	5285
HNRNPM	5258
COL9A3	5186
MAPKAP1	5130
ANOS1	5079
PIK3R2	5051
GTF2F1	5042
NCK2	5007
VAV3	4974
PCSK5	4881
HBEGF	4878
COL6A3	4861
ID1	4819
GRAP2	4746
PIK3CA	4697
PPP2R1A	4669
POLR2F	4646
SGK1	4642
HGS	4570
ELMO2	4507
PTK2	4506
SHC2	4499
UBC	4421
DUSP6	4367
APH1A	4198
EPS15	4189
MAPKAPK2	4176
SHC1	4173
ITGA2	4159
CDC37	4125
PAG1	4088
SHC3	4054
NRG1	4018
ATP6V1G1	3989
CRKL	3986
HNRNPF	3972
MAP2K5	3957
MAPK11	3955
SH2B3	3920
SOCS1	3886
GGA3	3846
KRAS	3760
MAPK13	3704
EPS15L1	3688
FGF2	3660
AKT1	3656
POLR2G	3581
DNM1	3526
DNAL4	3391
RAP1B	3331
RAB4B	3231
ADORA2A	3227
RPS6KA2	3177
NTRK3	3038
RPS6KA3	3012
EGR1	2965
HPN	2719
RALA	2686
JAK2	2599
EPGN	2579
RANBP10	2565
PTPRO	2485
PPP2R5D	2440
RASA1	2134
ATF2	2110
GALNT3	2006
EREG	1906
CAV1	1856
SPRY1	1831
IRS1	1806
FER	1777
HSPB1	1738
PIK3C3	1626
JUND	1561
POLR2C	1531
FOSB	1432
ARF6	1407
ITCH	1394
HSP90AA1	1348
NAB1	1315
BRAF	1314
STAM	1299
VRK3	1293
COL4A3	1268
TF	1172
PRKCA	1163
UBA52	1071
ELK1	1040
GABRG2	992
COL4A2	979
REST	945
CUL5	847
MST1	808
TIAM1	701
LAMB2	494
NELFB	385
AKT2	345
POLR2I	316
MLST8	304
TNS4	165
APOE	103
PTPN3	-46
ITGB1	-50
BAIAP2	-179
PTBP1	-195
PPP2R1B	-246
MEF2C	-319
ERBB3	-468
ERBIN	-585
EGR3	-690
DIAPH1	-704
LAMA1	-906
MAPK12	-946
STUB1	-1093
CDK5R1	-1166
PLAT	-1233
TCF12	-1268
COL6A1	-1276
MAPK7	-1294
CREB1	-1382
NOS3	-1718
POLR2K	-1792
NRG4	-1939
PLG	-1998
GABRB3	-2011
CALM1	-2048
LAMC3	-2093
EGR2	-2130
LAMA4	-2162
ATP6V1C2	-2222
TIAL1	-2300
DOCK7	-2432
CHEK1	-2534
POLR2B	-2536
PTPRU	-2718
AP2B1	-2748
POLR2H	-2817
FGFR4	-2892
LAMA5	-3030
POLR2A	-3105
MEF2D	-3132
DUSP7	-3253
HRAS	-3335
FRS2	-3430
COL4A4	-3622
FLRT2	-3651
AAMP	-3695
NRP2	-3980
FGF7	-3999
PIK3R4	-4040
POLR2D	-4058
VAV2	-4073
PAK3	-4194
DOCK3	-4198
CHD4	-4576
ARHGEF7	-4627
ADAM12	-4836
SPRY2	-4863
S100B	-5025
TIA1	-5138
FGFR1	-5335
JUP	-5541
MST1R	-5647
PGF	-5699
SOS1	-5714
MUC20	-5791
NCBP1	-5866
TRIB3	-5896
TLR9	-5909
HNRNPA1	-5998
PTPRK	-6407
DUSP4	-6432
FGF23	-6840
RPS27A	-6894
FLT4	-7288
RBFOX2	-7354
ITPR1	-7553
NTRK1	-7791
HNRNPH1	-7827
PSEN2	-7844
VEGFB	-7866
PRKCE	-8024
CILP	-8503
CTNND1	-8519
THBS4	-8534
PDGFB	-8575
ID3	-8629
SPRED1	-8664
STMN1	-8695
FGF22	-8733
TPH1	-8787
ESRP2	-8869
NRP1	-8872
FGF9	-8873
SRC	-9011
FGFBP3	-9205
ESR1	-9230
ATP6V1G2	-9275
FLT3LG	-9400
RICTOR	-9593
NCBP2	-9624
GRAP	-9703
PIK3R1	-9725
LAMA2	-9923
MTOR	-9948
ITPR3	-9955
COL9A2	-9974
RAPGEF1	-10033
WWP1	-10036
LRIG1	-10216
NAB2	-10348
COL6A2	-10386
CYFIP2	-10387
PLCG1	-10473
ITGA3	-10589
ABI2	-10893
THEM4	-10987
ID2	-11019
KIT	-11031
WWOX	-11144
PDE3B	-11323
MXD4	-11361
PDGFRB	-11452
ATP6V0E2	-11475
NCK1	-11488
LCK	-11492
PRKCZ	-11508
RPS6KA5	-11616
FGFR2	-11753
FYN	-11758
STAT1	-11769
AKT3	-11804
FGFRL1	-11838
PRKACB	-11857
PRR5	-11948
PIK3R3	-12037
RALGDS	-12117
YES1	-12143
ATP6V0A2	-12193
MATK	-12213
FGFBP2	-12222
PDGFD	-12226
PTPRS	-12262
ERBB2	-12281
AXL	-12293
SH2D2A	-12317

---

Platelet activation, signaling and aggregation

	829
set	Platelet activation, signaling and aggregation
setSize	221
pANOVA	1.26e-20
s.dist	0.363
p.adjustANOVA	1.71e-18

Top enriched genes

GeneID	Gene Rank
F5	9524
CYB5R1	9511
GNA15	9499
CD36	9486
GNG10	9436
CLU	9423
CD63	9330
GRB2	9320
QSOX1	9302
APLP2	9296
FERMT3	9287
ALDOA	9274
PLA2G4A	9234
MAPK14	9219
ACTN1	9210
SERPINA1	9179
LHFPL2	9147
APP	9123
SYK	9087
MAPK3	9078

Click HERE to show all gene set members

GeneID	Gene Rank
F5	9524
CYB5R1	9511
GNA15	9499
CD36	9486
GNG10	9436
CLU	9423
CD63	9330
GRB2	9320
QSOX1	9302
APLP2	9296
FERMT3	9287
ALDOA	9274
PLA2G4A	9234
MAPK14	9219
ACTN1	9210
SERPINA1	9179
LHFPL2	9147
APP	9123
SYK	9087
MAPK3	9078
STXBP2	9067
PIK3CB	9065
GNAQ	9024
PRKCD	9012
ITGA2B	8942
CRK	8941
TOR4A	8938
CLEC1B	8937
F13A1	8919
VTI1B	8892
GNG5	8866
HGF	8856
APBB1IP	8849
LAMP2	8803
SRGN	8781
RAC1	8720
TIMP1	8594
CLEC3B	8592
TLN1	8554
RHOG	8544
ARRB2	8517
SELP	8499
SYTL4	8410
ITGB3	8367
FN1	8294
GNB1	8278
EGF	8267
CFL1	8242
GNB2	8234
RHOA	8218
CAP1	8200
GAS6	8164
LY6G6F	8148
FCER1G	8143
ANXA5	8122
GNAI2	8094
ORM1	8082
GNAI3	8027
VAV1	8021
RAF1	7991
P2RY1	7929
SCCPDH	7913
CALU	7894
DGKG	7861
PROS1	7763
MMRN1	7746
PECAM1	7743
MGLL	7741
LYN	7728
GP1BB	7606
GP9	7589
SERPINE1	7580
ABCC4	7559
CDC42	7539
MAPK1	7520
TAGLN2	7451
STXBP3	7442
SPARC	7411
VEGFA	7389
VCL	7380
PIK3R6	7359
RAP1A	7319
GNB4	7138
HSPA5	7118
VEGFC	7057
PRKCB	7056
WDR1	7052
F8	6996
PSAP	6909
GP6	6890
GNG11	6612
VWF	6607
TUBA4A	6587
TMSB4X	6399
GTPBP2	6377
GP1BA	6320
PDPK1	6209
PTPN6	6176
PPBP	6029
CD9	6004
THBS1	5946
ITPR2	5919
DAGLB	5909
GNA13	5903
PTPN1	5797
PF4	5777
YWHAZ	5687
A1BG	5617
PFN1	5562
PHACTR2	5504
PDGFA	5484
PTPN11	5383
CSK	5285
RAC2	5238
ECM1	5213
TGFB1	5201
TBXA2R	5139
ACTN4	5132
PLCG2	5103
PIK3R2	5051
P2RY12	5031
OLA1	4999
VAV3	4974
F2RL3	4924
PIK3CA	4697
PTK2	4506
CD109	4343
GNG8	4339
SHC1	4173
AKT1	3656
RAB27B	3588
TIMP3	3463
ENDOD1	3416
GNA12	3399
GNAI1	3364
ALB	3339
RAP1B	3331
GNA11	3239
CHID1	2811
MPL	2709
MANF	2532
ADRA2A	2476
PLEK	2120
ARRB1	2098
PIK3CG	2046
CFD	2016
APOOL	1644
GP5	1281
TTN	1246
RHOB	1190
TF	1172
PRKCA	1163
GNG3	894
STX4	626
FLNA	547
GNB5	467
RAPGEF3	25
DGKD	-515
TMX3	-800
LCP2	-1167
F2RL2	-1922
TRPC6	-1948
PCYOX1L	-1974
PLG	-1998
CALM1	-2048
ABHD6	-2164
GNG4	-2175
PIK3R5	-2346
ORM2	-2594
MAGED2	-2729
GNB3	-2776
ITIH3	-2982
DGKH	-3171
AAMP	-3695
VAV2	-4073
SOD1	-4927
GNG7	-5049
DGKZ	-5636
SOS1	-5714
ITIH4	-6217
BRPF3	-6480
SERPINF2	-6601
PPIA	-6900
SELENOP	-7304
TGFB2	-7546
ITPR1	-7553
DGKA	-7619
TGFB3	-7674
GNG2	-7809
NHLRC2	-7843
VEGFB	-7866
PRKCE	-8024
RASGRP2	-8137
DGKQ	-8252
CDC37L1	-8413
TEX264	-8472
PDGFB	-8575
DAGLA	-8730
SRC	-9011
TRPC3	-9546
PIK3R1	-9725
A2M	-9822
F2R	-9847
ITPR3	-9955
FAM3C	-10007
DGKK	-10512
ABHD12	-10579
HABP4	-10972
CTSW	-11238
LAT	-11376
DGKE	-11387
SERPING1	-11444
LCK	-11492
PRKCZ	-11508
LGALS3BP	-11611
FYN	-11758
RASGRP1	-11817
PIK3R3	-12037
PRKCQ	-12039
GNGT2	-12070
PRKCH	-12254

---

Signaling by Interleukins

	1102
set	Signaling by Interleukins
setSize	386
pANOVA	1.86e-19
s.dist	0.267
p.adjustANOVA	2.3e-17

Top enriched genes

GeneID	Gene Rank
CSF2RA	9574
S100A12	9567
VAMP7	9549
SOCS3	9526
TALDO1	9505
CCR2	9503
SERPINB2	9491
CD36	9486
ITGAM	9453
PRKACA	9441
IL1RN	9432
CA1	9414
VIM	9399
IL1R2	9396
PTAFR	9392
LMNB1	9391
IL10	9385
FPR1	9379
MMP9	9370
TNFRSF1A	9347

Click HERE to show all gene set members

GeneID	Gene Rank
CSF2RA	9574.0
S100A12	9567.0
VAMP7	9549.0
SOCS3	9526.0
TALDO1	9505.0
CCR2	9503.0
SERPINB2	9491.0
CD36	9486.0
ITGAM	9453.0
PRKACA	9441.0
IL1RN	9432.0
CA1	9414.0
VIM	9399.0
IL1R2	9396.0
PTAFR	9392.0
LMNB1	9391.0
IL10	9385.0
FPR1	9379.0
MMP9	9370.0
TNFRSF1A	9347.0
MAOA	9325.0
DUSP3	9324.0
GRB2	9320.0
NKIRAS2	9308.0
BCL6	9299.0
IL17RA	9248.0
MAPK14	9219.0
IL10RB	9185.0
APP	9123.0
INPPL1	9115.0
GSTO1	9089.0
ALOX5	9088.0
SYK	9087.0
ARF1	9083.0
MAPK3	9078.0
STXBP2	9067.0
PIK3CB	9065.0
IL1R1	9030.0
MAP2K6	9010.0
HCK	8992.0
MAP2K1	8960.0
RHOU	8950.0
IRAK3	8947.0
CRK	8941.0
F13A1	8919.0
ITGB2	8908.0
CCR1	8857.0
HGF	8856.0
CEBPD	8826.0
BCL2L1	8798.0
CSF3R	8795.0
MAP2K3	8785.0
FOXO3	8729.0
TOLLIP	8668.0
TIMP1	8594.0
STX3	8585.0
PSMB7	8535.0
PSMD4	8498.0
P4HB	8452.0
ANXA2	8424.0
LCP1	8419.0
NOD2	8393.0
SOS2	8350.0
MAP3K3	8349.0
JAK3	8337.0
PSME3	8331.0
IRS2	8323.0
PPP2CA	8308.0
FN1	8294.0
MAPKAPK3	8255.0
CFL1	8242.0
IL6R	8229.0
PAK2	8226.0
HMOX1	8196.0
PSMB5	8188.0
PELI2	8166.0
CAPZA1	8165.0
STAT3	8152.0
PTPN12	8125.0
GAB2	8100.0
MYD88	8091.0
MEF2A	8030.0
VAV1	8021.0
PTK2B	8010.0
CHUK	7959.0
PSMD6	7881.0
OSM	7854.0
PIM1	7806.0
RPS6KA1	7800.0
FSCN1	7797.0
PPP2CB	7769.0
CSF2RB	7764.0
LCN2	7752.0
PELI3	7736.0
LYN	7728.0
PSMD9	7712.0
PTPN2	7634.0
CBL	7599.0
CDC42	7539.0
ANXA1	7530.0
MAPK1	7520.0
TEC	7488.0
PSMD2	7470.0
IL4R	7432.0
ITGAX	7429.0
HIF1A	7404.0
IL18	7395.0
VEGFA	7389.0
IL1RAP	7349.0
PSMA1	7346.0
PSMD1	7283.0
PSMB3	7265.0
IL27	7244.0
MMP1	7209.0
TYK2	7192.0
PSMA7	7174.0
MCL1	7168.0
PSMC1	7096.0
TAB2	7070.0
STAT5B	7011.0
STAT5A	6983.0
MAP2K4	6948.0
PSMB6	6927.0
JUNB	6889.0
PITPNA	6864.0
IL19	6862.0
NFKBIA	6835.0
PRTN3	6822.0
ICAM1	6797.0
H3C15	6780.5
UBB	6737.0
PSMF1	6724.0
CNN2	6719.0
PSMC6	6701.0
PTPN9	6633.0
PELI1	6596.0
MUC1	6589.0
PSMD12	6537.0
BATF	6501.0
NFKB1	6367.0
PSMD11	6296.0
FBXW11	6282.0
MAP3K8	6262.0
FOS	6179.0
PTPN6	6176.0
IRAK1	6159.0
PIK3CD	6096.0
PSMD7	6017.0
PSMD13	5991.0
PSMA6	5978.0
STAT6	5950.0
PTPN18	5944.0
TNFRSF1B	5916.0
PSMD8	5845.0
ATF1	5790.0
TAB1	5711.0
YWHAZ	5687.0
UBE2V1	5681.0
TNIP2	5630.0
MSN	5556.0
CANX	5526.0
CXCL1	5516.0
CXCL2	5509.0
IKBKG	5434.0
PSMA2	5433.0
PTPN11	5383.0
CTSG	5224.0
TGFB1	5201.0
IL13RA1	5174.0
PIK3R2	5051.0
CISH	4988.0
CNTF	4904.0
IL1B	4830.0
SMARCA4	4789.0
PIK3CA	4697.0
PSMD3	4693.0
PPP2R1A	4669.0
HAVCR2	4624.0
SOD2	4458.0
CDKN1A	4438.0
SEM1	4436.0
UBC	4421.0
PTGS2	4402.0
EBI3	4388.0
CTF1	4370.0
DUSP6	4367.0
SKP1	4349.0
IL18R1	4330.0
MAPKAPK2	4176.0
SHC1	4173.0
MAPK10	4136.0
SQSTM1	4123.0
PSMB2	4103.0
CASP1	4086.0
BIRC5	4082.0
NDN	4057.0
RBX1	4039.0
IL6ST	3996.0
CRKL	3986.0
HNRNPF	3972.0
JUN	3964.0
MAPK11	3955.0
SOCS1	3886.0
TCP1	3686.0
FGF2	3660.0
AKT1	3656.0
PSMD5	3507.0
IL27RA	3474.0
PSMB1	3422.0
HNRNPA2B1	3406.0
RAP1B	3331.0
SOCS5	3202.0
RPS6KA2	3177.0
TAB3	3165.0
TBK1	3159.0
RPS6KA3	3012.0
POMC	2971.0
LGALS9	2869.0
PSMD14	2703.0
PSMC2	2696.0
RALA	2686.0
IL1RL1	2644.0
JAK2	2599.0
IL15RA	2586.0
PSMB4	2552.0
COL1A2	2518.0
MAP3K7	2453.0
PPP2R5D	2440.0
MYC	2367.0
OPRM1	2186.0
ATF2	2110.0
HSP90B1	2086.0
PSMC3	2018.0
UBE2N	1951.0
NANOG	1867.0
IRS1	1806.0
CXCL8	1797.0
MAP2K7	1647.0
PSMD10	1646.0
POU2F1	1611.0
HSP90AA1	1348.0
AGER	1309.0
VRK3	1293.0
IL18RAP	1270.0
BOLA2	1240.0
UBA52	1071.0
RIPK2	1042.0
ELK1	1040.0
STX4	626.0
CSF1R	487.0
IL33	392.0
NKIRAS1	387.0
IL17RC	185.0
ITGB1	-50.0
CD86	-71.0
NFKBIB	-88.0
HMGB1	-200.0
TRAF6	-241.0
PPP2R1B	-246.0
MEF2C	-319.0
CASP3	-499.0
PSMA4	-538.0
NFKB2	-865.0
PSMC5	-948.0
RPLP0	-1054.0
PTPN23	-1197.0
CRLF1	-1280.0
MAPK7	-1294.0
CREB1	-1382.0
OSMR	-1693.0
RELA	-1807.0
TXLNA	-1837.0
CSF1	-2030.0
PTPN14	-2421.0
SOCS2	-2581.0
LAMA5	-3030.0
PSMB8	-3080.0
CCL3	-3120.0
DUSP7	-3253.0
PTPN20	-3554.0
AIP	-3644.0
FCER2	-3678.0
MIF	-3828.0
INPP5D	-3984.0
STX1A	-4061.0
BCL2	-4480.0
OPRD1	-4494.0
SOD1	-4927.0
BTRC	-4932.0
S100B	-5025.0
IGHE	-5174.0
IL17RE	-5274.0
IKBKB	-5290.0
IL15	-5313.0
PSMA3	-5314.0
CD4	-5320.0
IGHG1	-5669.0
SOS1	-5714.0
PSMB10	-5768.0
MTAP	-5771.0
PSME4	-6099.0
PSMA5	-6154.0
DUSP4	-6432.0
IL17RB	-6628.0
IL17C	-6676.0
IGHG4	-6718.0
CD80	-6837.0
CCND1	-6847.0
RPS27A	-6894.0
PPIA	-6900.0
BLNK	-6993.0
ZEB1	-7029.0
MAPK9	-7182.0
TNF	-7241.0
IL2RA	-7301.0
IL12A	-7399.0
PSMA8	-7559.0
IL31RA	-7869.0
RORC	-8272.0
IL7	-8618.0
IFNLR1	-8686.0
IRF4	-8965.0
CCR5	-8977.0
IL20RB	-9098.0
FOXO1	-9173.0
BRWD1	-9192.0
S1PR1	-9239.0
IL16	-9259.0
PSMC4	-9306.0
IL11RA	-9436.0
MAPK8	-9646.0
IRAK2	-9718.0
PIK3R1	-9725.0
IL32	-9735.0
IL23A	-9830.0
HSPA9	-9981.0
RAPGEF1	-10033.0
PSME1	-10138.0
SNRPA1	-10141.0
PTPN13	-10143.0
IL4	-10166.0
IFNG	-10320.0
IL7R	-10324.0
PSME2	-10415.0
ALOX15	-10452.0
SIGIRR	-10688.0
IL18BP	-10728.0
IL10RA	-10759.0
IL24	-10868.0
STAT2	-10885.0
HSPA8	-10913.0
TP53	-10936.0
PTPN7	-11022.0
CLCF1	-11060.0
JAK1	-11075.0
CCL5	-11152.0
HNRNPDL	-11221.0
IL5RA	-11247.0
PSMB9	-11362.0
CUL1	-11467.0
LCK	-11492.0
RAG1	-11517.0
SMAD3	-11541.0
RPS6KA5	-11616.0
VAMP2	-11692.0
FYN	-11758.0
STAT1	-11769.0
PDCD4	-11779.0
RORA	-11872.0
IL2RG	-11983.0
CCL4	-12010.0
IL12RB2	-12025.0
PIK3R3	-12037.0
IL3RA	-12063.0
IL12RB1	-12101.0
IL9R	-12104.0
PTPN4	-12133.0
GATA3	-12140.0
YES1	-12143.0
IL21R	-12176.0
NOD1	-12234.0
STAT4	-12265.0
CXCL10	-12284.0
CCL2	-12298.0
IL2RB	-12307.0
FASLG	-12319.0

---

Metabolism of proteins

	649
set	Metabolism of proteins
setSize	1719
pANOVA	6.35e-19
s.dist	0.129
p.adjustANOVA	7.21e-17

Top enriched genes

GeneID	Gene Rank
CSF2RA	9574
ADAMTS2	9573
FAM20A	9572
PPARG	9571
CTSA	9555
NPL	9548
ASGR2	9541
VCAN	9538
BST1	9529
SOCS3	9526
F5	9524
RAB32	9504
CPE	9496
FAM20C	9489
CTSD	9475
LAMC1	9473
FBXO9	9467
FBXL5	9458
KIF13A	9445
RAB13	9443

Click HERE to show all gene set members

GeneID	Gene Rank
CSF2RA	9574.0
ADAMTS2	9573.0
FAM20A	9572.0
PPARG	9571.0
CTSA	9555.0
NPL	9548.0
ASGR2	9541.0
VCAN	9538.0
BST1	9529.0
SOCS3	9526.0
F5	9524.0
RAB32	9504.0
CPE	9496.0
FAM20C	9489.0
CTSD	9475.0
LAMC1	9473.0
FBXO9	9467.0
FBXL5	9458.0
KIF13A	9445.0
RAB13	9443.0
GNG10	9436.0
ANPEP	9427.0
SNCA	9421.0
CKAP4	9420.0
XRN2	9415.0
SNX3	9383.0
TPST1	9377.0
H2BC21	9368.0
FSTL3	9363.0
RAB31	9353.0
MSRB1	9348.0
RHOT1	9337.0
QSOX1	9302.0
ATP6V0D1	9298.0
APLP2	9296.0
UIMC1	9295.0
ST6GALNAC3	9271.0
VNN2	9253.0
KLHL2	9252.0
SPTB	9250.0
CES1	9240.0
RAB3D	9231.0
PCSK9	9229.0
ARF4	9201.0
ASGR1	9191.0
SERPINA1	9179.0
H2BC12	9178.0
KDELR1	9163.0
FURIN	9162.0
DCTN2	9158.0
CD55	9157.0
MSRB2	9155.0
VNN1	9151.0
MITF	9148.0
NCSTN	9139.0
UBE2D1	9125.0
APP	9123.0
PHC2	9103.0
NEU1	9084.0
ARF1	9083.0
B3GNT8	9077.0
RAB1A	9075.0
LGALS1	9062.0
ACTB	9060.0
HDAC4	9057.0
GBA	9040.0
PNPLA2	9033.0
TGFA	9031.0
CTSZ	9001.0
IGFBP2	8973.0
SUMF1	8969.0
GALNT14	8963.0
RAD23B	8926.0
NUCB1	8917.0
RAB10	8915.0
B4GALT5	8909.0
ANK1	8897.0
GALNT2	8896.0
ALPL	8882.0
NUP58	8872.0
GNG5	8866.0
ERO1A	8853.0
EXOC6	8851.0
OS9	8845.0
PCMT1	8829.0
NSF	8815.0
TPP1	8814.0
NLRP3	8813.0
GSN	8805.0
CMAS	8802.0
ST3GAL2	8782.0
EDEM2	8778.0
TUBB2A	8777.0
RAB7A	8775.0
B3GNT5	8765.0
H3-3A	8754.0
MGAT4B	8742.0
FBXL19	8733.0
CDC34	8728.0
RAB11A	8715.0
UBE2D3	8710.0
ADAM10	8705.0
FKBP8	8702.0
RAB5C	8688.0
NRN1	8660.0
SIAH2	8657.0
GLB1	8652.0
ADAMTS3	8650.0
TGOLN2	8647.0
USP3	8644.0
SOCS6	8639.0
RNF146	8622.0
RAB2A	8597.0
TIMP1	8594.0
EDEM3	8573.0
UBE2R2	8564.0
TLN1	8554.0
SERP1	8546.0
PSMB7	8535.0
RNF135	8534.0
CAPZA2	8521.0
ARRB2	8517.0
PTEN	8516.0
ADORA2B	8515.0
RAB27A	8504.0
PSMD4	8498.0
PLAUR	8490.0
TNIP1	8471.0
DNAJC3	8468.0
SMAD1	8465.0
ATF6	8461.0
RAB20	8460.0
GCNT1	8453.0
P4HB	8452.0
FKBP9	8430.0
TXN	8414.0
RAB1B	8407.0
ACADVL	8405.0
RAB34	8401.0
NOD2	8393.0
UBE2J2	8389.0
DCTN4	8385.0
MRTFA	8376.0
AGTPBP1	8359.0
DCAF6	8347.0
PSME3	8331.0
COPA	8319.0
GALNT7	8316.0
RAB40C	8313.0
TGFBI	8304.0
FN1	8294.0
GNB1	8278.0
TRIM25	8276.0
ST8SIA4	8264.0
VDR	8258.0
TRIM27	8257.0
RAB3A	8247.0
GNB2	8234.0
RAB6A	8223.0
RHOA	8218.0
C1GALT1C1	8215.0
ANKRD9	8209.0
FUCA2	8195.0
PSMB5	8188.0
CAPZA1	8165.0
GAS6	8164.0
H2BC5	8163.0
STAT3	8152.0
KIF5B	8144.0
SEC24D	8130.0
CEBPB	8108.0
GNAI2	8094.0
EIF4G1	8081.0
H2BC11	8076.0
H2AC6	8070.0
CAPZB	8057.0
RAB4A	8050.0
GNAI3	8027.0
JOSD2	8025.0
NUP214	8011.0
RPN1	8009.0
EPAS1	8002.0
LTBP1	8000.0
SEC11A	7993.0
MAN1A1	7979.0
RNF7	7977.0
ARF5	7975.0
COPB2	7965.0
FSTL1	7961.0
NCOR2	7948.0
VDAC2	7947.0
NANS	7936.0
ATP6AP2	7934.0
UBE2W	7932.0
TTLL4	7924.0
COMMD9	7912.0
TMED7	7909.0
NUS1	7900.0
CALU	7894.0
RAB18	7893.0
TRAPPC1	7887.0
PSMD6	7881.0
DPH3	7842.0
WSB1	7840.0
CNIH1	7832.0
UBE2H	7815.0
GSK3A	7811.0
USP4	7809.0
ARF3	7798.0
MPDU1	7794.0
EIF4H	7786.0
SPTA1	7785.0
EXOSC4	7781.0
UBA3	7776.0
ETFB	7772.0
CSF2RB	7764.0
PROS1	7763.0
NFYC	7726.0
SPHK1	7724.0
SEC24A	7716.0
PSMD9	7712.0
MBD6	7711.0
TOP1	7680.0
H2AC11	7674.0
WSB2	7655.0
ACTR10	7652.0
PGA5	7651.0
USP10	7648.0
PDIA5	7646.0
ELOC	7637.0
COPG2	7636.0
MRPL28	7632.0
DYNC1I2	7629.0
HNRNPK	7619.0
UBE2L3	7612.0
PGA3	7610.0
LRRC41	7609.0
YOD1	7607.0
UBE2M	7590.0
ELOB	7586.0
KDELR2	7585.0
FBXO7	7577.0
EIF4A1	7550.0
H2BC4	7549.0
COPG1	7533.0
RXRA	7513.0
NR1H2	7512.0
FUCA1	7508.0
H2BC17	7502.0
ADAMTSL4	7487.0
PSMD2	7470.0
MSRA	7469.0
UBE2F	7462.0
AMFR	7452.0
TADA3	7448.0
PIAS1	7434.0
TUBA1A	7428.0
SEC23A	7416.0
ETF1	7409.0
HIF1A	7404.0
MELTF	7403.0
COMMD8	7400.0
COPB1	7399.0
MYDGF	7397.0
RAB33B	7385.0
DCTN6	7382.0
FPGT	7374.0
ARSB	7373.0
CARS1	7350.0
PSMA1	7346.0
TUBB4B	7341.0
WIPI1	7320.0
UBE2A	7315.0
SLC35A1	7309.0
RPL26L1	7295.0
PSMD1	7283.0
HDGF	7282.0
CARS2	7279.0
ARSD	7273.0
PSMB3	7265.0
MRPS36	7260.0
CCT5	7251.0
TUBA1C	7249.0
CHCHD1	7246.0
TFG	7240.0
MAVS	7231.0
CFP	7228.0
MMP1	7209.0
LYZ	7202.0
TMED9	7199.0
TAF10	7190.0
GALNT4	7188.0
UBA1	7187.0
STX5	7186.0
LMAN2	7178.0
PSMA7	7174.0
RAB5A	7166.0
TRAPPC3	7158.0
GNB4	7138.0
MCFD2	7136.0
RPN2	7135.0
UBE2B	7129.0
SEC61B	7125.0
HSPA5	7118.0
MRPL33	7102.0
PSMC1	7096.0
MRPL23	7094.0
RAB14	7090.0
ACTR1A	7088.0
IDE	7082.0
HERPUD1	7075.0
TADA2B	7067.0
RAB39A	7059.0
PIGS	7042.0
TUBA8	7030.0
SUMO3	7016.0
TSPAN14	7007.0
LMAN2L	7003.0
F8	6996.0
DYNC1LI1	6992.0
GARS1	6991.0
RTN4RL2	6985.0
PGA4	6980.0
COPE	6979.0
SUMO1	6973.0
DDOST	6972.0
VCP	6955.0
PSMB6	6927.0
CUL3	6924.0
RNF123	6899.0
WDTC1	6898.0
PPP6C	6887.0
CPM	6886.0
PPP2R5B	6870.0
UBE2E1	6853.0
MSRB3	6847.0
NFKBIA	6835.0
SEL1L	6834.0
UBE2K	6832.0
ST6GALNAC2	6828.0
EIF2S3	6808.0
DCP2	6806.0
RAB5B	6801.0
XRCC4	6793.0
TDG	6789.0
H3C15	6780.5
USP22	6761.0
IGFBP7	6753.0
FBXO11	6747.0
UBB	6737.0
GNAT2	6734.0
PSMF1	6724.0
RNF40	6702.0
PSMC6	6701.0
PIGF	6689.0
MYO5A	6685.0
SRP54	6678.0
ST3GAL6	6671.0
GORASP1	6670.0
MAN2A2	6669.0
SORL1	6654.0
COPS7A	6649.0
CCT8	6640.0
SSR1	6639.0
FBXW2	6635.0
CCDC22	6623.0
RAB8B	6617.0
GNG11	6612.0
SATB2	6611.0
RENBP	6608.0
RAD23A	6599.0
NEDD8	6597.0
MUC1	6589.0
TUBA4A	6587.0
RNF185	6584.0
GSPT1	6567.0
KBTBD7	6566.0
SAR1B	6562.0
PSMD12	6537.0
GALNT1	6518.0
SEC61A1	6517.0
RAB43	6507.0
PARK7	6496.0
FOXO4	6493.0
DCUN1D1	6468.0
CTNNB1	6463.0
PREB	6450.0
CSNK2A2	6430.0
BECN1	6423.0
CALR	6415.0
SRP14	6411.0
USP7	6410.0
H2BC18	6400.0
USP8	6383.0
COL7A1	6375.0
RARA	6365.0
TTLL7	6364.0
CTSH	6356.0
HNRNPC	6349.0
RRAGA	6344.0
TSTA3	6326.0
ASB7	6322.0
ATF4	6317.0
TSPAN33	6301.0
PSMD11	6296.0
FBXW11	6282.0
INO80C	6276.0
BRCA1	6273.0
APH1B	6248.0
RAB21	6237.0
GOLGA2	6217.0
HIPK2	6215.0
EP300	6208.0
CSNK2A1	6207.0
EIF2S2	6203.0
RGS6	6201.0
MGAT1	6190.0
STAM2	6183.0
LTF	6182.0
ANO8	6166.0
RAB6B	6149.0
COPS2	6147.0
AURKAIP1	6134.0
H2AZ1	6126.0
EIF4EBP1	6124.0
TMED2	6098.0
RNF181	6095.0
ZBED1	6085.0
BRCC3	6084.0
DCTN3	6080.0
GPAA1	6071.0
HDAC7	6070.0
MRPL53	6054.0
DYNLL1	6049.0
NSMCE1	6046.0
ITM2B	6042.0
COPS3	6040.0
USP15	6028.0
CHST8	6024.0
PSMD7	6017.0
SSR3	6015.0
VNN3	6013.0
DAD1	5994.0
PSMD13	5991.0
B3GNT2	5988.0
PSMA6	5978.0
CD59	5964.0
COMMD1	5956.0
P2RY2	5954.0
NSMCE2	5951.0
LAMB1	5948.0
THBS1	5946.0
PDIA6	5943.0
SEC22B	5939.0
BCL10	5931.0
ST3GAL4	5930.0
IARS2	5892.0
TPST2	5872.0
PSMD8	5845.0
PSENEN	5833.0
ALG14	5825.0
SEC13	5820.0
RNF20	5813.0
TUBB6	5794.0
ADD1	5789.0
APOA2	5784.0
CETN2	5754.0
DNAJB11	5736.0
RAB36	5722.0
TAB1	5711.0
EXOC1	5710.0
NTNG2	5664.0
EXOC4	5662.0
ARCN1	5661.0
EXTL3	5658.0
OXA1L	5638.0
TNIP2	5630.0
CTDSP2	5626.0
MIA2	5618.0
TMEM115	5605.0
FBXL13	5592.0
TUBA1B	5583.0
FBXL4	5572.0
COMMD5	5570.0
HDAC2	5569.0
SP3	5560.0
CEBPG	5551.0
TUBB1	5545.0
AP3M1	5544.0
USP9X	5542.0
B3GNTL1	5533.0
CANX	5526.0
CBX8	5523.0
RPS9	5496.0
AREG	5494.0
PIGX	5474.0
H2BC9	5461.0
H2BC15	5458.0
NARS1	5454.0
IKBKG	5434.0
PSMA2	5433.0
TTLL12	5426.0
MRPL30	5425.0
RAB24	5415.0
TRAPPC9	5414.0
PABPC1	5403.0
TFPT	5379.0
TBCA	5344.0
STAG2	5339.0
WAC	5331.0
PPP6R1	5328.0
ZDHHC2	5314.0
COMMD7	5313.0
GGCX	5306.0
VBP1	5304.0
PRKCSH	5300.0
YKT6	5277.0
TMEM132A	5273.0
SDC2	5257.0
TRAPPC5	5253.0
PIAS4	5248.0
CTSG	5224.0
METTL22	5217.0
FEM1C	5215.0
TGFB1	5201.0
CCNE2	5178.0
MTRF1L	5170.0
UBE2C	5168.0
KLHL5	5154.0
RAE1	5152.0
DCTN1	5143.0
UGGT1	5125.0
FBN1	5107.0
SRPRA	5104.0
CDC73	5093.0
SLC17A5	5092.0
UBE2E3	5089.0
KLHL21	5069.0
SUMO2	5062.0
USP12	5041.0
H2AC20	5039.0
UBE2G1	5016.0
KEAP1	5003.0
DCAF10	5002.0
EXOC7	4998.0
CISH	4988.0
GMDS	4987.0
ASB8	4973.0
GCNT3	4970.0
KDM1B	4958.0
SMAD2	4939.0
DDIT3	4938.0
MRPS5	4922.0
AR	4913.0
FBXL20	4911.0
MRPL51	4910.0
MRPS10	4894.0
EIF4E	4892.0
SEC61G	4837.0
UBE2S	4810.0
EIF3H	4804.0
DPM2	4786.0
AOPEP	4783.0
IKBKE	4779.0
EXOC3	4767.0
EIF3I	4766.0
UGGT2	4756.0
FBXO30	4752.0
BIRC2	4749.0
HDAC3	4734.0
UBE2D2	4721.0
PSMD3	4693.0
SEC16A	4687.0
PTRH2	4665.0
MRPL44	4640.0
EIF3M	4633.0
NRIP1	4616.0
SUDS3	4587.0
HGS	4570.0
NCOA1	4563.0
NUP50	4544.0
RPL3L	4539.0
FBXL15	4533.0
SRP9	4515.0
MRPS16	4510.0
C4A	4491.0
FEM1B	4479.0
TUFM	4470.0
RAB11B	4445.0
SEM1	4436.0
KCTD6	4434.0
USP48	4430.0
KLHDC3	4427.0
UBC	4421.0
COPS5	4415.0
ING2	4405.0
SPCS3	4397.0
RAB19	4386.0
TPGS1	4377.0
DCUN1D3	4368.0
RFT1	4358.0
B4GALT1	4354.0
SKP1	4349.0
DNMT3B	4348.0
CD109	4343.0
FCGR3B	4340.0
GNG8	4339.0
EIF2S1	4338.0
COMMD10	4322.0
COG7	4321.0
SRP19	4319.0
VDAC1	4300.0
HCFC1	4299.0
SP100	4293.0
DYNC1LI2	4253.0
PEX5	4238.0
STS	4231.0
PMM1	4217.0
DYNC1I1	4211.0
TRAPPC6B	4201.0
APH1A	4198.0
USO1	4192.0
NAPG	4190.0
EXOC5	4181.0
MDM2	4179.0
RAB9A	4177.0
SHC1	4173.0
PDIA3	4172.0
MRPL47	4147.0
STT3A	4129.0
PSMB2	4103.0
SULT1A3	4094.0
SRD5A3	4089.0
CDC20	4087.0
BIRC5	4082.0
COPZ1	4081.0
MRPL58	4077.0
SENP2	4070.0
RBX1	4039.0
RAB35	4030.0
FBXL8	4029.0
ADRM1	4003.0
CSNK2B	3987.0
SSPO	3985.0
RAB42	3951.0
GFM2	3950.0
PPARGC1A	3934.0
OTOA	3930.0
TMEM129	3929.0
GMPPA	3925.0
FN3K	3894.0
SERPINA10	3885.0
TGFBR2	3881.0
RAB8A	3874.0
LMNA	3863.0
GGA3	3846.0
ARFGAP3	3807.0
MRPS34	3794.0
CLSPN	3790.0
ZRANB1	3772.0
VHL	3742.0
PFDN5	3728.0
MFGE8	3718.0
MRPL52	3714.0
PFDN1	3713.0
TCP1	3686.0
SEC24B	3655.0
PIGB	3638.0
BACE1	3627.0
KIN	3605.0
RTF1	3600.0
SCFD1	3593.0
RAB27B	3588.0
METTL21A	3575.0
RNF2	3573.0
FBXO17	3537.0
MTFMT	3527.0
PAF1	3523.0
PSMD5	3507.0
NFYA	3506.0
AURKA	3503.0
ARSA	3499.0
UBA6	3490.0
INHBA	3489.0
FFAR4	3462.0
CREBBP	3460.0
AGBL5	3441.0
TUBB3	3437.0
PSMB1	3422.0
FOXK2	3396.0
FBXL18	3388.0
ASB13	3383.0
CTR9	3381.0
GNAI1	3364.0
ALB	3339.0
PPP6R3	3323.0
KTN1	3322.0
ASB1	3318.0
EIF2B2	3297.0
APC	3284.0
SPCS2	3275.0
MRPL37	3270.0
COMMD2	3267.0
RAB4B	3231.0
PEX14	3229.0
ADORA2A	3227.0
ERCC8	3222.0
MRPL13	3212.0
SOCS5	3202.0
NAGK	3197.0
DDA1	3186.0
SSR4	3169.0
NUP37	3153.0
RNF152	3152.0
DDB1	3148.0
SENP8	3133.0
NUP98	3124.0
PIGZ	3106.0
SPCS1	3099.0
DERL2	3093.0
MUL1	3083.0
KLK2	3082.0
PEX2	3062.0
UBE2V2	2997.0
TARS1	2993.0
POMC	2971.0
MBTPS1	2958.0
CDC25A	2948.0
TOP2A	2945.0
GNAZ	2927.0
MRPS35	2906.0
DOLPP1	2886.0
TOPORS	2871.0
ETFBKMT	2854.0
CUL4B	2847.0
SSR2	2840.0
MTIF3	2833.0
TBCB	2831.0
MRPS24	2788.0
TMED3	2779.0
MRPL45	2742.0
SLC35C1	2739.0
CFTR	2738.0
SEMA5B	2735.0
EIF2B4	2732.0
KHSRP	2722.0
MRPS7	2714.0
PSMD14	2703.0
MAGT1	2698.0
RNF139	2697.0
PSMC2	2696.0
PTP4A2	2669.0
USP49	2654.0
ALG12	2650.0
EIF3D	2641.0
MBD5	2621.0
IGFBP6	2617.0
SAFB	2611.0
EIF3L	2591.0
DPM3	2581.0
GCNT7	2568.0
CUL2	2559.0
PSMB4	2552.0
CTSC	2547.0
MRPL12	2488.0
ADRA2A	2476.0
MAP3K7	2453.0
FBXO40	2452.0
SPSB1	2416.0
CSNK1D	2412.0
MYC	2367.0
GGA1	2327.0
MLEC	2315.0
CHM	2291.0
MSLN	2273.0
BTBD1	2261.0
CBX4	2237.0
PPA2	2208.0
EIF5	2204.0
DPAGT1	2191.0
MT-RNR2	2190.0
CST3	2157.0
MRPL18	2146.0
EIF3A	2137.0
RPS27L	2117.0
ARRB1	2098.0
CCP110	2089.0
HSP90B1	2086.0
MRPL16	2045.0
SRP68	2041.0
PSMC3	2018.0
MRPL36	2008.0
GALNT3	2006.0
MBD1	2003.0
UCHL3	1998.0
PPA1	1957.0
UBE2N	1951.0
TUBA4B	1950.0
EIF3J	1939.0
FCSK	1937.0
EIF3E	1934.0
FEM1A	1916.0
LSAMP	1892.0
UBXN1	1884.0
FARSA	1882.0
COPS4	1865.0
ASXL2	1861.0
PIGN	1846.0
MRPS22	1843.0
MRPL22	1809.0
CXCL8	1797.0
KIFC3	1774.0
SFTPB	1764.0
ZBTB17	1742.0
PIGQ	1741.0
PRMT3	1720.0
RAD21	1719.0
MRPS23	1700.0
GADD45GIP1	1689.0
ST8SIA5	1677.0
CCNA2	1676.0
MGAT2	1670.0
COPS6	1663.0
STAMBP	1654.0
PSMD10	1646.0
ALG6	1645.0
TGFBR1	1642.0
ATXN3	1623.0
UBXN7	1609.0
THRB	1600.0
DPM1	1591.0
MRPS15	1583.0
ASB9	1560.0
EIF3K	1521.0
NEGR1	1512.0
CDK1	1480.0
CCDC8	1474.0
MRPS28	1454.0
MRPS11	1426.0
PMM2	1425.0
OTUB1	1419.0
RTN4RL1	1406.0
TSFM	1396.0
MRPL15	1392.0
NAPA	1385.0
ASB3	1343.0
SLC34A2	1301.0
STAM	1299.0
SHISA5	1280.0
KLHL9	1277.0
ZBTB16	1252.0
EIF4B	1233.0
PFDN4	1200.0
TF	1172.0
SEC31A	1144.0
RAB23	1143.0
BAP1	1122.0
DARS1	1111.0
PFDN2	1110.0
NCOA2	1109.0
EIF1AX	1100.0
B4GALNT2	1082.0
UBA52	1071.0
APEH	1061.0
TSPAN5	1049.0
RIPK2	1042.0
FBXL3	1026.0
RBBP5	1009.0
SYVN1	997.0
PIGT	987.0
AURKB	959.0
EIF3F	925.0
GNG3	894.0
EIF3G	880.0
DCUN1D5	877.0
GNAT1	874.0
PPARA	865.0
MRPL21	860.0
USP30	853.0
CUL5	847.0
GALNT16	840.0
ADAMTSL3	838.0
NUP62	772.0
DNAJB9	748.0
CNIH2	727.0
MRPS18A	707.0
SMC1A	659.0
HLA-B	658.0
POMT2	607.0
NR3C1	600.0
B4GALT4	587.0
TRMT112	586.0
PEX13	582.0
EIF5A	577.0
CCNA1	575.0
RAB44	540.0
YY1	529.0
CAMKMT	506.0
DHPS	499.0
LAMB2	494.0
EXOSC3	489.0
ST3GAL3	485.0
VDAC3	483.0
GNB5	467.0
MRPL19	454.0
CCT4	417.0
HDAC1	394.0
IL33	392.0
DTL	391.0
SEC16B	351.0
TMED10	328.0
VCPKMT	298.0
JOSD1	290.0
EEF2	289.0
EIF3C	274.0
FBXW5	244.0
MRPS18C	186.0
USP25	154.0
WDR5	123.0
DPH5	119.0
QARS1	118.0
GALNT15	117.0
APOE	103.0
RPL36AL	91.0
WDR61	87.0
LEO1	84.0
MBTPS2	77.0
PIGM	69.0
SLC30A6	34.0
COG4	15.0
KLF4	11.0
KLHL13	-4.0
B3GALNT2	-20.0
EXOC8	-23.0
TBC1D20	-49.0
RPLP1	-65.0
HYOU1	-105.0
EDEM1	-133.0
GOSR1	-160.0
CREBRF	-203.0
YIF1A	-204.0
RPS4Y1	-222.0
TRAF6	-241.0
RWDD3	-252.0
TTF1	-255.0
VCPIP1	-274.0
RPS24	-282.0
MT-RNR1	-288.0
FAU	-402.0
COG8	-406.0
EIF2B1	-423.0
MRPL20	-438.0
SEC23IP	-469.0
USP19	-475.0
TNKS2	-512.0
PRSS21	-527.0
PSMA4	-538.0
NPPA	-569.0
BET1	-631.0
ARL2	-643.0
CCT6A	-648.0
MANEA	-658.0
FBXO41	-664.0
ALG5	-694.0
RARS2	-695.0
OTULIN	-705.0
UBE2I	-746.0
MTIF2	-760.0
ICMT	-766.0
PGM3	-773.0
GALNT6	-797.0
RANBP2	-808.0
USP33	-811.0
OTUB2	-818.0
ST6GALNAC4	-827.0
EEF1D	-828.0
NFKB2	-865.0
RAB12	-874.0
AIMP2	-907.0
USP34	-934.0
BABAM1	-937.0
PSMC5	-948.0
EXOSC1	-976.0
GANAB	-1004.0
RPL15	-1017.0
MRPL3	-1023.0
RAD52	-1033.0
RPLP0	-1054.0
MRPL34	-1088.0
WDR20	-1123.0
FBXO15	-1131.0
COMMD6	-1143.0
CREB3L2	-1160.0
TTLL2	-1176.0
GALNT5	-1186.0
MDM4	-1218.0
RPL8	-1242.0
ALG3	-1284.0
FBXL12	-1327.0
PIAS3	-1330.0
DAP3	-1340.0
CHML	-1348.0
MAN2A1	-1350.0
PDCL	-1358.0
MRPL41	-1362.0
ALG2	-1381.0
GAN	-1402.0
COMMD3	-1441.0
RPS26	-1443.0
ST6GAL2	-1456.0
EEF1G	-1457.0
RPL28	-1469.0
PIGC	-1482.0
SRP72	-1486.0
BGLAP	-1498.0
GOSR2	-1504.0
RAB7B	-1528.0
MRPL57	-1562.0
CP	-1599.0
XBP1	-1602.0
NR4A2	-1625.0
RPL22L1	-1643.0
DCAF7	-1650.0
ATXN7	-1665.0
DOHH	-1680.0
SLC34A1	-1698.0
RPS13	-1759.0
PIGV	-1800.0
RELA	-1807.0
RPL9	-1827.0
SELENOS	-1848.0
CDCA8	-1850.0
NICN1	-1857.0
EEF1A1P5	-1860.0
MRPL4	-1898.0
TSPAN15	-1940.0
POMK	-1943.0
ARFGAP1	-1962.0
SMC3	-1982.0
INO80B	-1989.0
PLG	-1998.0
MAN1A2	-2017.0
RPL7	-2018.0
CSF1	-2030.0
MRPL54	-2032.0
PUM2	-2043.0
CALM1	-2048.0
DHDDS	-2090.0
MGAT4C	-2101.0
RPS8	-2138.0
EEF1E1	-2141.0
KDELR3	-2154.0
MGAT3	-2157.0
CXXC1	-2173.0
GNG4	-2175.0
ASB14	-2209.0
HIF3A	-2292.0
MUCL1	-2297.0
TRIM13	-2320.0
FBXO6	-2328.0
PFDN6	-2336.0
TRAPPC2L	-2337.0
KAT2B	-2393.0
TTLL3	-2412.0
SUZ12	-2444.0
RABGGTA	-2455.0
DCAF11	-2469.0
SLC30A5	-2484.0
CCT3	-2491.0
RAB3B	-2524.0
CD52	-2553.0
MRPL43	-2560.0
HLA-A	-2578.0
SOCS2	-2581.0
MARS1	-2590.0
TAF9B	-2602.0
SEC24C	-2615.0
MUC4	-2624.0
SERPIND1	-2671.0
MRPL14	-2714.0
TOP2B	-2735.0
TOMM20	-2745.0
NFRKB	-2751.0
NAPB	-2763.0
GNB3	-2776.0
ASB6	-2780.0
MRPL48	-2792.0
DNMT3A	-2812.0
CALB1	-2900.0
MTA1	-2917.0
RPL27	-2934.0
SIAH1	-3004.0
MUC6	-3012.0
B3GNT9	-3042.0
RPL39	-3047.0
MOGS	-3075.0
NUP85	-3077.0
PSMB8	-3080.0
MRPL27	-3097.0
MGAT5	-3137.0
GALNT11	-3147.0
CCT7	-3168.0
NEURL2	-3175.0
GALNT10	-3198.0
EPRS1	-3205.0
TPGS2	-3216.0
MUC16	-3285.0
TBCE	-3304.0
COG5	-3318.0
ADAMTS5	-3336.0
RPL23	-3352.0
CUL7	-3371.0
ZNF350	-3381.0
RPL6	-3382.0
MME	-3410.0
NR1H3	-3418.0
BARD1	-3441.0
SKIV2L	-3443.0
SPTBN5	-3449.0
RPL13	-3461.0
OBSL1	-3558.0
THSD4	-3568.0
DARS2	-3590.0
RPL4	-3592.0
RPL29	-3604.0
KBTBD6	-3608.0
ALG11	-3638.0
PROZ	-3658.0
MARCHF6	-3663.0
ALG8	-3682.0
DOLK	-3691.0
RPS15	-3698.0
RPL7A	-3699.0
ADAMTS17	-3723.0
MT-TV	-3737.0
MRPS12	-3742.0
FBXO22	-3743.0
NGLY1	-3744.0
NEU3	-3800.0
PAPPA	-3813.0
RAB41	-3915.0
CCDC59	-3921.0
NAT8B	-3928.0
USP47	-3964.0
LARGE2	-3975.0
RPL37A	-4004.0
TTL	-4007.0
B3GNT3	-4021.0
DYNLL2	-4042.0
RING1	-4045.0
MRPL11	-4059.0
STX1A	-4061.0
YARS2	-4075.0
BMP4	-4078.0
TULP4	-4088.0
SPSB2	-4099.0
RPS21	-4115.0
POMGNT2	-4128.0
TTLL5	-4135.0
DCTN5	-4140.0
PCGF2	-4179.0
CREB3	-4220.0
MDGA1	-4223.0
NAPSA	-4226.0
ENAM	-4228.0
ADAMTS13	-4230.0
KBTBD8	-4233.0
RAB22A	-4243.0
NR1I2	-4247.0
RNF168	-4269.0
SEC22C	-4285.0
ARFGEF2	-4292.0
EEF1B2	-4298.0
UCN	-4308.0
SMC6	-4310.0
C1GALT1	-4318.0
GBF1	-4322.0
TNC	-4350.0
DIS3	-4360.0
EXOSC5	-4414.0
RAB26	-4445.0
SLC30A7	-4483.0
RPL31	-4507.0
RPS2	-4509.0
MRPL35	-4569.0
RPS16	-4570.0
GPS1	-4577.0
RNF103	-4584.0
MUC5B	-4618.0
RPL5	-4631.0
COMMD4	-4635.0
RPS28	-4647.0
TRAM1	-4649.0
EIF5B	-4660.0
CBX2	-4693.0
RCE1	-4695.0
ERAL1	-4696.0
RPS3A	-4702.0
RPL22	-4738.0
BLM	-4764.0
WARS2	-4777.0
MRPS14	-4785.0
ARSG	-4809.0
CUL4A	-4814.0
RARS1	-4820.0
DCUN1D2	-4849.0
TRIM28	-4905.0
ACTR8	-4911.0
MAN1B1	-4926.0
BTRC	-4932.0
ANK3	-4974.0
CRHR2	-4975.0
MRPS31	-4979.0
RPS7	-5016.0
GNG7	-5049.0
RPL18	-5054.0
EEF1A1	-5073.0
SEC22A	-5080.0
FOXK1	-5089.0
FBXO27	-5112.0
ST6GALNAC1	-5118.0
OTUD5	-5121.0
PIGP	-5133.0
SPTBN2	-5189.0
EEF1A2	-5193.0
TTLL11	-5196.0
FUOM	-5217.0
PARN	-5227.0
COG3	-5230.0
INO80D	-5235.0
RABGGTB	-5240.0
GNE	-5250.0
TECTA	-5257.0
USP14	-5260.0
BTBD6	-5265.0
RPL36	-5287.0
TRAF3	-5296.0
CDKN2A	-5302.0
PSMA3	-5314.0
GFM1	-5318.0
FOLR2	-5394.0
TCF7L2	-5419.0
KARS1	-5423.0
GOLGB1	-5425.0
RPL17	-5464.0
RPS5	-5478.0
RPS14	-5485.0
MGAT4A	-5545.0
SCMH1	-5553.0
RAB15	-5587.0
ARSJ	-5603.0
NUP42	-5622.0
DCAF13	-5627.0
PLA2G7	-5638.0
ASB4	-5677.0
MRPS17	-5682.0
RPS10	-5686.0
B4GAT1	-5693.0
RPS15A	-5695.0
MRPL40	-5698.0
LONP2	-5741.0
MRPL1	-5742.0
PSMB10	-5768.0
MUC20	-5791.0
RPS3	-5833.0
AIMP1	-5849.0
ARFGAP2	-5850.0
MRPL55	-5860.0
LARGE1	-5864.0
COG6	-5872.0
RPL24	-5882.0
RPL38	-5890.0
DDX17	-5894.0
MVD	-5926.0
CUL9	-5934.0
VARS2	-5944.0
SEH1L	-5957.0
SARS1	-5960.0
RPS4X	-5969.0
SPSB3	-5976.0
DDX11	-5981.0
RPS12	-5985.0
YARS1	-5996.0
RPL18A	-6029.0
PCNA	-6038.0
INCENP	-6043.0
FBXL14	-6062.0
PIGK	-6067.0
RPL35A	-6080.0
PSME4	-6099.0
RPS6	-6100.0
B4GALT2	-6126.0
KLHL11	-6134.0
USP5	-6141.0
PSMA5	-6154.0
NUDT14	-6189.0
RPSA	-6219.0
RPS17	-6223.0
RPL19	-6242.0
RPS25	-6246.0
MRPS26	-6255.0
RPL11	-6275.0
RPS23	-6279.0
LARS1	-6282.0
ANKRD28	-6311.0
RPL27A	-6321.0
ACE	-6322.0
NUP153	-6325.0
MIA3	-6330.0
THRA	-6373.0
RPL37	-6401.0
FBXO10	-6411.0
LYPD5	-6424.0
STAG1	-6429.0
MRPL24	-6434.0
MAN1C1	-6459.0
RAB9B	-6471.0
RPL21	-6481.0
RNF5	-6497.0
ADAMTS14	-6509.0
RPL14	-6518.0
H2BU1	-6519.0
GGA2	-6523.0
MRPL38	-6532.0
UBA2	-6547.0
CTBP1	-6549.0
CAND1	-6550.0
GFPT1	-6551.0
RPL10	-6562.0
RPL32	-6577.0
PARS2	-6619.0
RPL26	-6636.0
RPL10A	-6644.0
PLA2G4B	-6650.0
PEX10	-6685.0
OGT	-6687.0
USP21	-6692.0
FBXW7	-6709.0
FBXL16	-6710.0
ITIH2	-6715.0
ASB16	-6721.0
USP13	-6723.0
TRRAP	-6755.0
ADAMTS6	-6772.0
SENP5	-6786.0
RPL34	-6807.0
TRAPPC4	-6836.0
FGF23	-6840.0
MRPS2	-6876.0
RPL41	-6877.0
RPS27A	-6894.0
RPLP2	-6915.0
ENGASE	-6927.0
DPP4	-6952.0
GOLM1	-6954.0
CPA3	-6984.0
RPL30	-6995.0
B2M	-7019.0
RPS19	-7037.0
RPL12	-7038.0
GALNT8	-7062.0
TPR	-7100.0
RPS11	-7122.0
GMPPB	-7145.0
SMC5	-7199.0
MXRA8	-7275.0
PIGA	-7297.0
LYPD3	-7300.0
POM121C	-7305.0
MRPL2	-7376.0
BET1L	-7385.0
ACTL6A	-7411.0
FBXW9	-7412.0
SPTBN1	-7419.0
THSD1	-7421.0
GALNT9	-7426.0
AXIN2	-7434.0
RPL36A	-7442.0
MYSM1	-7444.0
ST3GAL1	-7452.0
VARS1	-7454.0
MRPL42	-7490.0
DAG1	-7502.0
USP44	-7504.0
PSMA8	-7559.0
INO80E	-7569.0
SATB1	-7601.0
PIAS2	-7624.0
RPS18	-7641.0
NRN1L	-7644.0
GPLD1	-7660.0
POLB	-7666.0
HARS2	-7680.0
IGFBP4	-7686.0
HSPG2	-7708.0
TTLL1	-7719.0
ALG13	-7736.0
EXOC2	-7746.0
LRR1	-7760.0
APOL1	-7788.0
RPS29	-7794.0
ADAMTSL5	-7800.0
GNG2	-7809.0
PHC1	-7816.0
DYNC1H1	-7822.0
NUP133	-7839.0
WARS1	-7853.0
UBE2G2	-7879.0
ALG10	-7908.0
ST8SIA1	-7927.0
UCHL5	-7955.0
PIGG	-7960.0
COG2	-8023.0
KLK1	-8035.0
USP16	-8051.0
SENP1	-8071.0
ALG10B	-8085.0
RPL13A	-8123.0
PHC3	-8154.0
SBSPON	-8155.0
EIF3B	-8173.0
FBXO2	-8199.0
RPL35	-8239.0
POM121	-8263.0
MEN1	-8265.0
SMAD4	-8273.0
KIF5C	-8297.0
ASNS	-8299.0
SKP2	-8307.0
RECK	-8311.0
MRPL10	-8328.0
EIF2B3	-8331.0
AAAS	-8337.0
MRPS30	-8347.0
MRPL50	-8351.0
SHPRH	-8364.0
MCRS1	-8365.0
KIF5A	-8378.0
THSD7A	-8381.0
FARSB	-8391.0
SAE1	-8410.0
LARS2	-8434.0
AARS1	-8438.0
KLHL42	-8445.0
HARS1	-8446.0
DPH6	-8447.0
FBXW12	-8474.0
RPL3	-8478.0
NUP54	-8521.0
ADAMTS16	-8527.0
MBOAT4	-8590.0
TNIP3	-8599.0
POMT1	-8604.0
TTLL13P	-8610.0
TOMM70	-8631.0
AGBL3	-8699.0
PEX12	-8717.0
RUVBL1	-8726.0
CCT2	-8727.0
UBE2T	-8732.0
FKBP14	-8736.0
MRPL46	-8764.0
INO80	-8786.0
PGAP1	-8798.0
MRPS21	-8799.0
NARS2	-8810.0
RAB38	-8811.0
TNKS	-8839.0
TRAPPC2	-8851.0
COPS8	-8868.0
PML	-8888.0
RPS20	-8922.0
SEC11C	-8947.0
ALG1	-8949.0
PIGO	-8956.0
RAB30	-8959.0
MRPS27	-8973.0
B4GALT6	-8981.0
RPL39L	-8982.0
AGBL2	-8988.0
FARS2	-9031.0
CYLD	-9037.0
MRPL32	-9048.0
DERL1	-9113.0
RAB2B	-9119.0
CBX5	-9139.0
PIGU	-9190.0
CNIH3	-9196.0
ESR1	-9230.0
FBXO44	-9242.0
PSMC4	-9306.0
FBXL22	-9326.0
WRAP53	-9336.0
MRRF	-9358.0
TUBB4A	-9359.0
LMO7	-9377.0
TATDN2	-9440.0
PIGH	-9445.0
ERN1	-9447.0
CHD3	-9466.0
SRPRB	-9468.0
RPL23A	-9477.0
CCNF	-9479.0
TRAPPC10	-9516.0
MRPS33	-9566.0
SEMA5A	-9572.0
NUP43	-9595.0
NPM1	-9596.0
GNPNAT1	-9605.0
RPS27	-9651.0
IGFBP3	-9669.0
TBCD	-9670.0
GHRL	-9675.0
NANP	-9677.0
MRPL49	-9680.0
MRPS25	-9684.0
WFS1	-9727.0
FUT8	-9752.0
NR2C1	-9766.0
EIF2B5	-9776.0
BMI1	-9787.0
DDX5	-9806.0
GALNT12	-9814.0
ALG9	-9826.0
DCAF8	-9832.0
UHRF2	-9833.0
RGS9	-9835.0
DCAF5	-9844.0
DCUN1D4	-9871.0
TBCC	-9883.0
CREB3L4	-9908.0
COPS7B	-9938.0
EEF2KMT	-9943.0
ATF3	-9951.0
NFYB	-9957.0
GFPT2	-9963.0
SPRN	-9966.0
USP37	-10003.0
FBXW8	-10006.0
EXOSC6	-10009.0
NOP58	-10035.0
GSPT2	-10116.0
TUBA3D	-10117.0
GNAO1	-10133.0
PSME1	-10138.0
PRKDC	-10173.0
ASXL1	-10181.0
MPI	-10185.0
IGFALS	-10190.0
NUP35	-10206.0
SPON1	-10222.0
SMURF2	-10250.0
PROC	-10273.0
PTCD3	-10274.0
NUP155	-10291.0
NR3C2	-10304.0
CASP8AP2	-10306.0
AXIN1	-10310.0
GCNT4	-10319.0
STAMBPL1	-10340.0
OTUD7A	-10349.0
KLHL25	-10363.0
KAT2A	-10374.0
RAB29	-10377.0
B3GNT4	-10382.0
NUP160	-10383.0
PSME2	-10415.0
EXOSC9	-10425.0
HIC1	-10453.0
EIF2AK3	-10491.0
MAT2B	-10550.0
NUP107	-10570.0
DAXX	-10582.0
DPH2	-10601.0
MRPL39	-10618.0
B4GALT3	-10619.0
HLTF	-10626.0
OTUD3	-10628.0
AMDHD2	-10643.0
SIN3A	-10648.0
LMCD1	-10663.0
POFUT2	-10670.0
DPH7	-10675.0
N6AMT1	-10679.0
LMAN1	-10699.0
SARS2	-10716.0
ERO1B	-10723.0
NUP210	-10725.0
HERC2	-10745.0
L3MBTL2	-10749.0
EXOSC7	-10756.0
RNF144A	-10763.0
DNAJC24	-10767.0
MRPS18B	-10782.0
FBXO32	-10797.0
MRPL9	-10806.0
ADAMTS10	-10823.0
BIRC3	-10830.0
FBXO21	-10844.0
EXOSC2	-10865.0
SEC61A2	-10873.0
MRPL17	-10876.0
NAE1	-10877.0
MUC12	-10883.0
TP53BP1	-10894.0
EIF4A2	-10909.0
HSPA8	-10913.0
ADAMTS4	-10919.0
TRAPPC6A	-10921.0
RCN1	-10928.0
TSPYL2	-10933.0
TP53	-10936.0
SFTPD	-10938.0
NSMCE4A	-10940.0
KCTD7	-10994.0
STX17	-11009.0
RAB33A	-11034.0
NUP88	-11046.0
COPZ2	-11047.0
KLHL22	-11058.0
UBE2Z	-11084.0
GZMH	-11086.0
MRPS6	-11096.0
ACTR5	-11119.0
ZNF131	-11121.0
DCAF4	-11122.0
EXTL2	-11129.0
TNFAIP3	-11131.0
MARS2	-11143.0
LYPD2	-11146.0
USP20	-11173.0
RIPK1	-11184.0
ARSK	-11217.0
FN3KRP	-11231.0
KLHL3	-11236.0
MRPS9	-11249.0
NUP205	-11250.0
DCAF17	-11276.0
EXOSC8	-11326.0
DPH1	-11331.0
USP24	-11342.0
RAB40B	-11344.0
RAB39B	-11350.0
PSMB9	-11362.0
UBE2L6	-11415.0
CCT6B	-11422.0
SPTAN1	-11438.0
CUL1	-11467.0
USP42	-11486.0
IFIH1	-11499.0
KLHL20	-11500.0
NOP56	-11502.0
XPC	-11529.0
ADAMTS1	-11537.0
SMAD3	-11541.0
H2AW	-11543.0
NUP188	-11545.0
ST8SIA6	-11578.0
PARP1	-11586.0
FBXW4	-11593.0
TRAF2	-11594.0
DDB2	-11598.0
NSMCE3	-11613.0
AARS2	-11618.0
ST3GAL5	-11628.0
WDR48	-11633.0
UBE2Q2	-11642.0
CCNE1	-11655.0
PIGW	-11656.0
B3GLCT	-11660.0
DCAF16	-11664.0
RANGAP1	-11665.0
VAMP2	-11692.0
PIGL	-11695.0
NUP93	-11700.0
EID3	-11719.0
IARS1	-11740.0
ABCA3	-11748.0
TARS2	-11755.0
EIF5A2	-11759.0
RAD18	-11793.0
RAB37	-11814.0
CHST10	-11858.0
FBXO4	-11867.0
RORA	-11872.0
ADRB2	-11879.0
POMGNT1	-11883.0
ST6GAL1	-11887.0
FBXO31	-11894.0
SMAD7	-11905.0
WRN	-11954.0
GATA6	-11955.0
ST6GALNAC6	-11958.0
RPA1	-11962.0
EARS2	-11972.0
DDX58	-11974.0
MDC1	-11988.0
ASB2	-12015.0
NUB1	-12017.0
COG1	-12057.0
SUMF2	-12066.0
GNGT2	-12070.0
OTUD7B	-12072.0
RBBP7	-12085.0
NDC1	-12113.0
GATA3	-12140.0
XPNPEP2	-12154.0
UAP1	-12160.0
DNMT1	-12192.0
USP18	-12221.0
NOD1	-12234.0
C3	-12243.0
SPON2	-12248.0
LY6E	-12249.0
PRSS23	-12259.0
B3GNT7	-12264.0
USP11	-12268.0
USP28	-12269.0
CCL2	-12298.0

---

Post-translational protein modification

	841
set	Post-translational protein modification
setSize	1194
pANOVA	1.26e-18
s.dist	0.151
p.adjustANOVA	1.32e-16

Top enriched genes

GeneID	Gene Rank
ADAMTS2	9573
FAM20A	9572
PPARG	9571
CTSA	9555
NPL	9548
ASGR2	9541
VCAN	9538
BST1	9529
SOCS3	9526
F5	9524
RAB32	9504
FAM20C	9489
LAMC1	9473
FBXO9	9467
FBXL5	9458
RAB13	9443
CKAP4	9420
SNX3	9383
TPST1	9377
H2BC21	9368

Click HERE to show all gene set members

GeneID	Gene Rank
ADAMTS2	9573
FAM20A	9572
PPARG	9571
CTSA	9555
NPL	9548
ASGR2	9541
VCAN	9538
BST1	9529
SOCS3	9526
F5	9524
RAB32	9504
FAM20C	9489
LAMC1	9473
FBXO9	9467
FBXL5	9458
RAB13	9443
CKAP4	9420
SNX3	9383
TPST1	9377
H2BC21	9368
FSTL3	9363
RAB31	9353
RHOT1	9337
QSOX1	9302
APLP2	9296
UIMC1	9295
ST6GALNAC3	9271
VNN2	9253
KLHL2	9252
SPTB	9250
RAB3D	9231
PCSK9	9229
ARF4	9201
ASGR1	9191
SERPINA1	9179
H2BC12	9178
KDELR1	9163
FURIN	9162
DCTN2	9158
CD55	9157
VNN1	9151
MITF	9148
UBE2D1	9125
APP	9123
PHC2	9103
NEU1	9084
ARF1	9083
B3GNT8	9077
RAB1A	9075
LGALS1	9062
ACTB	9060
HDAC4	9057
PNPLA2	9033
TGFA	9031
CTSZ	9001
SUMF1	8969
GALNT14	8963
RAD23B	8926
NUCB1	8917
RAB10	8915
B4GALT5	8909
ANK1	8897
GALNT2	8896
ALPL	8882
NUP58	8872
OS9	8845
NSF	8815
NLRP3	8813
CMAS	8802
ST3GAL2	8782
EDEM2	8778
TUBB2A	8777
RAB7A	8775
B3GNT5	8765
MGAT4B	8742
FBXL19	8733
CDC34	8728
RAB11A	8715
UBE2D3	8710
ADAM10	8705
FKBP8	8702
RAB5C	8688
NRN1	8660
SIAH2	8657
GLB1	8652
ADAMTS3	8650
TGOLN2	8647
USP3	8644
SOCS6	8639
RNF146	8622
RAB2A	8597
TIMP1	8594
EDEM3	8573
UBE2R2	8564
PSMB7	8535
RNF135	8534
CAPZA2	8521
ARRB2	8517
PTEN	8516
RAB27A	8504
PSMD4	8498
PLAUR	8490
TNIP1	8471
DNAJC3	8468
SMAD1	8465
RAB20	8460
GCNT1	8453
P4HB	8452
RAB1B	8407
RAB34	8401
NOD2	8393
UBE2J2	8389
DCTN4	8385
MRTFA	8376
AGTPBP1	8359
DCAF6	8347
PSME3	8331
COPA	8319
GALNT7	8316
RAB40C	8313
FN1	8294
TRIM25	8276
ST8SIA4	8264
VDR	8258
TRIM27	8257
RAB3A	8247
RAB6A	8223
RHOA	8218
C1GALT1C1	8215
ANKRD9	8209
FUCA2	8195
PSMB5	8188
CAPZA1	8165
GAS6	8164
H2BC5	8163
SEC24D	8130
H2BC11	8076
H2AC6	8070
CAPZB	8057
RAB4A	8050
JOSD2	8025
NUP214	8011
RPN1	8009
EPAS1	8002
LTBP1	8000
MAN1A1	7979
RNF7	7977
ARF5	7975
COPB2	7965
FSTL1	7961
NCOR2	7948
VDAC2	7947
NANS	7936
UBE2W	7932
TTLL4	7924
COMMD9	7912
TMED7	7909
NUS1	7900
CALU	7894
RAB18	7893
TRAPPC1	7887
PSMD6	7881
DPH3	7842
WSB1	7840
CNIH1	7832
UBE2H	7815
USP4	7809
ARF3	7798
MPDU1	7794
SPTA1	7785
UBA3	7776
ETFB	7772
PROS1	7763
SEC24A	7716
PSMD9	7712
MBD6	7711
TOP1	7680
H2AC11	7674
WSB2	7655
ACTR10	7652
USP10	7648
ELOC	7637
COPG2	7636
DYNC1I2	7629
HNRNPK	7619
UBE2L3	7612
LRRC41	7609
YOD1	7607
UBE2M	7590
ELOB	7586
KDELR2	7585
FBXO7	7577
H2BC4	7549
COPG1	7533
RXRA	7513
NR1H2	7512
FUCA1	7508
H2BC17	7502
ADAMTSL4	7487
PSMD2	7470
UBE2F	7462
AMFR	7452
TADA3	7448
PIAS1	7434
TUBA1A	7428
SEC23A	7416
HIF1A	7404
MELTF	7403
COMMD8	7400
COPB1	7399
RAB33B	7385
DCTN6	7382
FPGT	7374
ARSB	7373
PSMA1	7346
TUBB4B	7341
UBE2A	7315
SLC35A1	7309
PSMD1	7283
ARSD	7273
PSMB3	7265
TUBA1C	7249
TFG	7240
MAVS	7231
CFP	7228
TMED9	7199
TAF10	7190
GALNT4	7188
UBA1	7187
STX5	7186
LMAN2	7178
PSMA7	7174
RAB5A	7166
TRAPPC3	7158
MCFD2	7136
RPN2	7135
UBE2B	7129
PSMC1	7096
RAB14	7090
ACTR1A	7088
IDE	7082
TADA2B	7067
RAB39A	7059
PIGS	7042
SUMO3	7016
LMAN2L	7003
F8	6996
DYNC1LI1	6992
RTN4RL2	6985
COPE	6979
SUMO1	6973
DDOST	6972
VCP	6955
PSMB6	6927
CUL3	6924
RNF123	6899
WDTC1	6898
PPP6C	6887
CPM	6886
UBE2E1	6853
NFKBIA	6835
SEL1L	6834
UBE2K	6832
ST6GALNAC2	6828
RAB5B	6801
XRCC4	6793
TDG	6789
USP22	6761
IGFBP7	6753
FBXO11	6747
UBB	6737
PSMF1	6724
RNF40	6702
PSMC6	6701
PIGF	6689
ST3GAL6	6671
GORASP1	6670
MAN2A2	6669
COPS7A	6649
FBXW2	6635
CCDC22	6623
RAB8B	6617
SATB2	6611
RENBP	6608
RAD23A	6599
NEDD8	6597
MUC1	6589
RNF185	6584
KBTBD7	6566
SAR1B	6562
PSMD12	6537
GALNT1	6518
RAB43	6507
PARK7	6496
FOXO4	6493
DCUN1D1	6468
PREB	6450
BECN1	6423
CALR	6415
USP7	6410
H2BC18	6400
USP8	6383
COL7A1	6375
RARA	6365
TTLL7	6364
HNRNPC	6349
RRAGA	6344
TSTA3	6326
ASB7	6322
PSMD11	6296
FBXW11	6282
INO80C	6276
BRCA1	6273
RAB21	6237
GOLGA2	6217
HIPK2	6215
EP300	6208
MGAT1	6190
STAM2	6183
ANO8	6166
RAB6B	6149
COPS2	6147
TMED2	6098
RNF181	6095
ZBED1	6085
BRCC3	6084
DCTN3	6080
GPAA1	6071
HDAC7	6070
DYNLL1	6049
NSMCE1	6046
COPS3	6040
USP15	6028
CHST8	6024
PSMD7	6017
VNN3	6013
DAD1	5994
PSMD13	5991
B3GNT2	5988
PSMA6	5978
CD59	5964
COMMD1	5956
NSMCE2	5951
LAMB1	5948
THBS1	5946
PDIA6	5943
SEC22B	5939
BCL10	5931
ST3GAL4	5930
TPST2	5872
PSMD8	5845
ALG14	5825
SEC13	5820
RNF20	5813
TUBB6	5794
APOA2	5784
CETN2	5754
RAB36	5722
TAB1	5711
NTNG2	5664
ARCN1	5661
TNIP2	5630
MIA2	5618
TMEM115	5605
FBXL13	5592
TUBA1B	5583
FBXL4	5572
COMMD5	5570
HDAC2	5569
SP3	5560
TUBB1	5545
USP9X	5542
B3GNTL1	5533
CANX	5526
CBX8	5523
AREG	5494
PIGX	5474
H2BC9	5461
H2BC15	5458
IKBKG	5434
PSMA2	5433
TTLL12	5426
RAB24	5415
TRAPPC9	5414
TFPT	5379
STAG2	5339
WAC	5331
PPP6R1	5328
COMMD7	5313
GGCX	5306
PRKCSH	5300
YKT6	5277
TMEM132A	5273
SDC2	5257
TRAPPC5	5253
PIAS4	5248
METTL22	5217
FEM1C	5215
TGFB1	5201
UBE2C	5168
KLHL5	5154
RAE1	5152
DCTN1	5143
UGGT1	5125
FBN1	5107
CDC73	5093
SLC17A5	5092
UBE2E3	5089
KLHL21	5069
SUMO2	5062
USP12	5041
H2AC20	5039
UBE2G1	5016
KEAP1	5003
DCAF10	5002
CISH	4988
GMDS	4987
ASB8	4973
GCNT3	4970
KDM1B	4958
SMAD2	4939
AR	4913
FBXL20	4911
UBE2S	4810
DPM2	4786
IKBKE	4779
UGGT2	4756
FBXO30	4752
BIRC2	4749
UBE2D2	4721
PSMD3	4693
SEC16A	4687
PTRH2	4665
NRIP1	4616
SUDS3	4587
HGS	4570
NCOA1	4563
NUP50	4544
FBXL15	4533
C4A	4491
FEM1B	4479
RAB11B	4445
SEM1	4436
KCTD6	4434
USP48	4430
UBC	4421
COPS5	4415
ING2	4405
RAB19	4386
TPGS1	4377
DCUN1D3	4368
RFT1	4358
B4GALT1	4354
SKP1	4349
DNMT3B	4348
CD109	4343
FCGR3B	4340
COMMD10	4322
COG7	4321
VDAC1	4300
HCFC1	4299
SP100	4293
DYNC1LI2	4253
PEX5	4238
STS	4231
PMM1	4217
DYNC1I1	4211
TRAPPC6B	4201
USO1	4192
NAPG	4190
MDM2	4179
RAB9A	4177
PDIA3	4172
STT3A	4129
PSMB2	4103
SRD5A3	4089
CDC20	4087
BIRC5	4082
COPZ1	4081
SENP2	4070
RBX1	4039
RAB35	4030
FBXL8	4029
ADRM1	4003
SSPO	3985
RAB42	3951
PPARGC1A	3934
OTOA	3930
TMEM129	3929
GMPPA	3925
FN3K	3894
SERPINA10	3885
TGFBR2	3881
RAB8A	3874
ARFGAP3	3807
CLSPN	3790
ZRANB1	3772
VHL	3742
MFGE8	3718
SEC24B	3655
PIGB	3638
KIN	3605
RTF1	3600
SCFD1	3593
RAB27B	3588
METTL21A	3575
RNF2	3573
FBXO17	3537
PAF1	3523
PSMD5	3507
AURKA	3503
ARSA	3499
UBA6	3490
CREBBP	3460
AGBL5	3441
TUBB3	3437
PSMB1	3422
FOXK2	3396
FBXL18	3388
ASB13	3383
CTR9	3381
ALB	3339
PPP6R3	3323
KTN1	3322
ASB1	3318
APC	3284
COMMD2	3267
RAB4B	3231
PEX14	3229
ERCC8	3222
SOCS5	3202
NAGK	3197
DDA1	3186
NUP37	3153
RNF152	3152
DDB1	3148
SENP8	3133
NUP98	3124
PIGZ	3106
DERL2	3093
MUL1	3083
PEX2	3062
UBE2V2	2997
MBTPS1	2958
CDC25A	2948
TOP2A	2945
DOLPP1	2886
TOPORS	2871
ETFBKMT	2854
CUL4B	2847
TMED3	2779
SLC35C1	2739
CFTR	2738
SEMA5B	2735
PSMD14	2703
MAGT1	2698
RNF139	2697
PSMC2	2696
PTP4A2	2669
USP49	2654
ALG12	2650
MBD5	2621
SAFB	2611
DPM3	2581
GCNT7	2568
CUL2	2559
PSMB4	2552
CTSC	2547
MAP3K7	2453
FBXO40	2452
SPSB1	2416
CSNK1D	2412
MYC	2367
MLEC	2315
CHM	2291
MSLN	2273
BTBD1	2261
CBX4	2237
DPAGT1	2191
CST3	2157
ARRB1	2098
CCP110	2089
HSP90B1	2086
PSMC3	2018
GALNT3	2006
MBD1	2003
UCHL3	1998
UBE2N	1951
FCSK	1937
FEM1A	1916
LSAMP	1892
UBXN1	1884
COPS4	1865
ASXL2	1861
PIGN	1846
PIGQ	1741
PRMT3	1720
RAD21	1719
ST8SIA5	1677
CCNA2	1676
MGAT2	1670
COPS6	1663
STAMBP	1654
PSMD10	1646
ALG6	1645
TGFBR1	1642
ATXN3	1623
UBXN7	1609
THRB	1600
DPM1	1591
ASB9	1560
NEGR1	1512
CDK1	1480
CCDC8	1474
PMM2	1425
OTUB1	1419
RTN4RL1	1406
NAPA	1385
ASB3	1343
STAM	1299
SHISA5	1280
KLHL9	1277
ZBTB16	1252
TF	1172
SEC31A	1144
RAB23	1143
BAP1	1122
NCOA2	1109
B4GALNT2	1082
UBA52	1071
RIPK2	1042
FBXL3	1026
RBBP5	1009
SYVN1	997
PIGT	987
AURKB	959
DCUN1D5	877
PPARA	865
USP30	853
CUL5	847
GALNT16	840
ADAMTSL3	838
NUP62	772
CNIH2	727
SMC1A	659
HLA-B	658
POMT2	607
NR3C1	600
B4GALT4	587
PEX13	582
EIF5A	577
CCNA1	575
RAB44	540
YY1	529
CAMKMT	506
DHPS	499
LAMB2	494
ST3GAL3	485
VDAC3	483
HDAC1	394
IL33	392
DTL	391
SEC16B	351
TMED10	328
VCPKMT	298
JOSD1	290
EEF2	289
FBXW5	244
USP25	154
WDR5	123
DPH5	119
GALNT15	117
APOE	103
WDR61	87
LEO1	84
PIGM	69
COG4	15
KLHL13	-4
B3GALNT2	-20
TBC1D20	-49
EDEM1	-133
GOSR1	-160
TRAF6	-241
RWDD3	-252
VCPIP1	-274
COG8	-406
SEC23IP	-469
USP19	-475
TNKS2	-512
PRSS21	-527
PSMA4	-538
BET1	-631
MANEA	-658
FBXO41	-664
ALG5	-694
OTULIN	-705
UBE2I	-746
ICMT	-766
PGM3	-773
GALNT6	-797
RANBP2	-808
USP33	-811
OTUB2	-818
ST6GALNAC4	-827
NFKB2	-865
RAB12	-874
USP34	-934
BABAM1	-937
PSMC5	-948
GANAB	-1004
RAD52	-1033
WDR20	-1123
FBXO15	-1131
COMMD6	-1143
TTLL2	-1176
GALNT5	-1186
MDM4	-1218
ALG3	-1284
FBXL12	-1327
PIAS3	-1330
CHML	-1348
MAN2A1	-1350
ALG2	-1381
GAN	-1402
COMMD3	-1441
ST6GAL2	-1456
PIGC	-1482
BGLAP	-1498
GOSR2	-1504
RAB7B	-1528
CP	-1599
NR4A2	-1625
DCAF7	-1650
ATXN7	-1665
DOHH	-1680
PIGV	-1800
RELA	-1807
SELENOS	-1848
CDCA8	-1850
NICN1	-1857
POMK	-1943
ARFGAP1	-1962
SMC3	-1982
INO80B	-1989
MAN1A2	-2017
CSF1	-2030
PUM2	-2043
CALM1	-2048
DHDDS	-2090
MGAT4C	-2101
KDELR3	-2154
MGAT3	-2157
ASB14	-2209
HIF3A	-2292
MUCL1	-2297
TRIM13	-2320
FBXO6	-2328
TRAPPC2L	-2337
KAT2B	-2393
TTLL3	-2412
SUZ12	-2444
RABGGTA	-2455
DCAF11	-2469
RAB3B	-2524
CD52	-2553
HLA-A	-2578
SOCS2	-2581
TAF9B	-2602
SEC24C	-2615
MUC4	-2624
SERPIND1	-2671
TOP2B	-2735
TOMM20	-2745
NFRKB	-2751
NAPB	-2763
ASB6	-2780
DNMT3A	-2812
MTA1	-2917
MUC6	-3012
B3GNT9	-3042
MOGS	-3075
NUP85	-3077
PSMB8	-3080
MGAT5	-3137
GALNT11	-3147
NEURL2	-3175
GALNT10	-3198
TPGS2	-3216
MUC16	-3285
COG5	-3318
ADAMTS5	-3336
CUL7	-3371
ZNF350	-3381
NR1H3	-3418
BARD1	-3441
SPTBN5	-3449
OBSL1	-3558
THSD4	-3568
KBTBD6	-3608
ALG11	-3638
PROZ	-3658
MARCHF6	-3663
ALG8	-3682
DOLK	-3691
ADAMTS17	-3723
FBXO22	-3743
NGLY1	-3744
NEU3	-3800
RAB41	-3915
USP47	-3964
LARGE2	-3975
TTL	-4007
B3GNT3	-4021
DYNLL2	-4042
RING1	-4045
BMP4	-4078
TULP4	-4088
SPSB2	-4099
POMGNT2	-4128
TTLL5	-4135
DCTN5	-4140
PCGF2	-4179
MDGA1	-4223
ENAM	-4228
ADAMTS13	-4230
KBTBD8	-4233
RAB22A	-4243
NR1I2	-4247
RNF168	-4269
SEC22C	-4285
SMC6	-4310
C1GALT1	-4318
GBF1	-4322
TNC	-4350
RAB26	-4445
RPS2	-4509
GPS1	-4577
RNF103	-4584
MUC5B	-4618
COMMD4	-4635
CBX2	-4693
RCE1	-4695
BLM	-4764
ARSG	-4809
CUL4A	-4814
DCUN1D2	-4849
TRIM28	-4905
ACTR8	-4911
MAN1B1	-4926
BTRC	-4932
ANK3	-4974
EEF1A1	-5073
SEC22A	-5080
FOXK1	-5089
FBXO27	-5112
ST6GALNAC1	-5118
OTUD5	-5121
PIGP	-5133
SPTBN2	-5189
TTLL11	-5196
FUOM	-5217
COG3	-5230
INO80D	-5235
RABGGTB	-5240
GNE	-5250
TECTA	-5257
USP14	-5260
BTBD6	-5265
TRAF3	-5296
CDKN2A	-5302
PSMA3	-5314
FOLR2	-5394
GOLGB1	-5425
MGAT4A	-5545
SCMH1	-5553
RAB15	-5587
ARSJ	-5603
NUP42	-5622
DCAF13	-5627
ASB4	-5677
B4GAT1	-5693
PSMB10	-5768
MUC20	-5791
ARFGAP2	-5850
LARGE1	-5864
COG6	-5872
DDX17	-5894
MVD	-5926
CUL9	-5934
SEH1L	-5957
SPSB3	-5976
PCNA	-6038
INCENP	-6043
FBXL14	-6062
PIGK	-6067
PSME4	-6099
B4GALT2	-6126
KLHL11	-6134
USP5	-6141
PSMA5	-6154
NUDT14	-6189
ANKRD28	-6311
NUP153	-6325
MIA3	-6330
THRA	-6373
FBXO10	-6411
LYPD5	-6424
STAG1	-6429
MAN1C1	-6459
RAB9B	-6471
RNF5	-6497
ADAMTS14	-6509
H2BU1	-6519
UBA2	-6547
CTBP1	-6549
CAND1	-6550
GFPT1	-6551
PEX10	-6685
OGT	-6687
USP21	-6692
FBXW7	-6709
FBXL16	-6710
ITIH2	-6715
ASB16	-6721
USP13	-6723
TRRAP	-6755
ADAMTS6	-6772
SENP5	-6786
TRAPPC4	-6836
FGF23	-6840
RPS27A	-6894
ENGASE	-6927
GOLM1	-6954
GALNT8	-7062
TPR	-7100
GMPPB	-7145
SMC5	-7199
MXRA8	-7275
PIGA	-7297
LYPD3	-7300
POM121C	-7305
BET1L	-7385
ACTL6A	-7411
FBXW9	-7412
SPTBN1	-7419
THSD1	-7421
GALNT9	-7426
AXIN2	-7434
MYSM1	-7444
ST3GAL1	-7452
DAG1	-7502
USP44	-7504
PSMA8	-7559
INO80E	-7569
SATB1	-7601
PIAS2	-7624
NRN1L	-7644
GPLD1	-7660
POLB	-7666
IGFBP4	-7686
TTLL1	-7719
ALG13	-7736
LRR1	-7760
APOL1	-7788
ADAMTSL5	-7800
PHC1	-7816
DYNC1H1	-7822
NUP133	-7839
UBE2G2	-7879
ALG10	-7908
ST8SIA1	-7927
UCHL5	-7955
PIGG	-7960
COG2	-8023
USP16	-8051
SENP1	-8071
ALG10B	-8085
PHC3	-8154
SBSPON	-8155
FBXO2	-8199
POM121	-8263
MEN1	-8265
SMAD4	-8273
SKP2	-8307
RECK	-8311
AAAS	-8337
SHPRH	-8364
MCRS1	-8365
THSD7A	-8381
SAE1	-8410
KLHL42	-8445
DPH6	-8447
FBXW12	-8474
NUP54	-8521
ADAMTS16	-8527
TNIP3	-8599
POMT1	-8604
TTLL13P	-8610
TOMM70	-8631
AGBL3	-8699
PEX12	-8717
RUVBL1	-8726
UBE2T	-8732
INO80	-8786
PGAP1	-8798
RAB38	-8811
TNKS	-8839
TRAPPC2	-8851
COPS8	-8868
PML	-8888
ALG1	-8949
PIGO	-8956
RAB30	-8959
B4GALT6	-8981
AGBL2	-8988
CYLD	-9037
DERL1	-9113
RAB2B	-9119
CBX5	-9139
PIGU	-9190
CNIH3	-9196
ESR1	-9230
FBXO44	-9242
PSMC4	-9306
FBXL22	-9326
TUBB4A	-9359
LMO7	-9377
PIGH	-9445
CHD3	-9466
CCNF	-9479
TRAPPC10	-9516
SEMA5A	-9572
NUP43	-9595
NPM1	-9596
GNPNAT1	-9605
IGFBP3	-9669
NANP	-9677
WFS1	-9727
FUT8	-9752
NR2C1	-9766
BMI1	-9787
DDX5	-9806
GALNT12	-9814
ALG9	-9826
DCAF8	-9832
UHRF2	-9833
DCAF5	-9844
DCUN1D4	-9871
COPS7B	-9938
EEF2KMT	-9943
GFPT2	-9963
SPRN	-9966
USP37	-10003
FBXW8	-10006
NOP58	-10035
TUBA3D	-10117
PSME1	-10138
PRKDC	-10173
ASXL1	-10181
MPI	-10185
NUP35	-10206
SPON1	-10222
SMURF2	-10250
PROC	-10273
NUP155	-10291
NR3C2	-10304
CASP8AP2	-10306
AXIN1	-10310
GCNT4	-10319
STAMBPL1	-10340
OTUD7A	-10349
KLHL25	-10363
KAT2A	-10374
RAB29	-10377
B3GNT4	-10382
NUP160	-10383
PSME2	-10415
HIC1	-10453
MAT2B	-10550
NUP107	-10570
DAXX	-10582
DPH2	-10601
B4GALT3	-10619
HLTF	-10626
OTUD3	-10628
AMDHD2	-10643
SIN3A	-10648
POFUT2	-10670
DPH7	-10675
LMAN1	-10699
NUP210	-10725
HERC2	-10745
L3MBTL2	-10749
RNF144A	-10763
DNAJC24	-10767
FBXO32	-10797
ADAMTS10	-10823
BIRC3	-10830
FBXO21	-10844
NAE1	-10877
MUC12	-10883
TP53BP1	-10894
HSPA8	-10913
ADAMTS4	-10919
TRAPPC6A	-10921
RCN1	-10928
TP53	-10936
NSMCE4A	-10940
KCTD7	-10994
STX17	-11009
RAB33A	-11034
NUP88	-11046
COPZ2	-11047
KLHL22	-11058
UBE2Z	-11084
ACTR5	-11119
ZNF131	-11121
DCAF4	-11122
TNFAIP3	-11131
LYPD2	-11146
USP20	-11173
RIPK1	-11184
ARSK	-11217
FN3KRP	-11231
KLHL3	-11236
NUP205	-11250
DCAF17	-11276
DPH1	-11331
USP24	-11342
RAB40B	-11344
RAB39B	-11350
PSMB9	-11362
SPTAN1	-11438
CUL1	-11467
USP42	-11486
IFIH1	-11499
KLHL20	-11500
XPC	-11529
ADAMTS1	-11537
SMAD3	-11541
H2AW	-11543
NUP188	-11545
ST8SIA6	-11578
PARP1	-11586
FBXW4	-11593
TRAF2	-11594
DDB2	-11598
NSMCE3	-11613
ST3GAL5	-11628
WDR48	-11633
UBE2Q2	-11642
PIGW	-11656
B3GLCT	-11660
DCAF16	-11664
RANGAP1	-11665
PIGL	-11695
NUP93	-11700
EID3	-11719
EIF5A2	-11759
RAD18	-11793
RAB37	-11814
CHST10	-11858
FBXO4	-11867
RORA	-11872
ADRB2	-11879
POMGNT1	-11883
ST6GAL1	-11887
FBXO31	-11894
SMAD7	-11905
WRN	-11954
ST6GALNAC6	-11958
RPA1	-11962
DDX58	-11974
MDC1	-11988
ASB2	-12015
NUB1	-12017
COG1	-12057
SUMF2	-12066
OTUD7B	-12072
RBBP7	-12085
NDC1	-12113
GATA3	-12140
XPNPEP2	-12154
UAP1	-12160
DNMT1	-12192
USP18	-12221
NOD1	-12234
C3	-12243
SPON2	-12248
LY6E	-12249
PRSS23	-12259
B3GNT7	-12264
USP11	-12268
USP28	-12269

---

Response to elevated platelet cytosolic Ca2+

	1010
set	Response to elevated platelet cytosolic Ca2+
setSize	110
pANOVA	1.59e-16
s.dist	0.455
p.adjustANOVA	1.55e-14

Top enriched genes

GeneID	Gene Rank
F5	9524
CYB5R1	9511
CD36	9486
CLU	9423
CD63	9330
QSOX1	9302
APLP2	9296
FERMT3	9287
ALDOA	9274
ACTN1	9210
SERPINA1	9179
LHFPL2	9147
APP	9123
STXBP2	9067
ITGA2B	8942
TOR4A	8938
F13A1	8919
VTI1B	8892
HGF	8856
LAMP2	8803

Click HERE to show all gene set members

GeneID	Gene Rank
F5	9524
CYB5R1	9511
CD36	9486
CLU	9423
CD63	9330
QSOX1	9302
APLP2	9296
FERMT3	9287
ALDOA	9274
ACTN1	9210
SERPINA1	9179
LHFPL2	9147
APP	9123
STXBP2	9067
ITGA2B	8942
TOR4A	8938
F13A1	8919
VTI1B	8892
HGF	8856
LAMP2	8803
SRGN	8781
TIMP1	8594
CLEC3B	8592
TLN1	8554
SELP	8499
SYTL4	8410
ITGB3	8367
FN1	8294
EGF	8267
CFL1	8242
CAP1	8200
GAS6	8164
LY6G6F	8148
ANXA5	8122
ORM1	8082
SCCPDH	7913
CALU	7894
PROS1	7763
MMRN1	7746
PECAM1	7743
SERPINE1	7580
ABCC4	7559
TAGLN2	7451
STXBP3	7442
SPARC	7411
VEGFA	7389
VCL	7380
HSPA5	7118
VEGFC	7057
PRKCB	7056
WDR1	7052
F8	6996
PSAP	6909
VWF	6607
TUBA4A	6587
TMSB4X	6399
GTPBP2	6377
PPBP	6029
CD9	6004
THBS1	5946
PF4	5777
A1BG	5617
PFN1	5562
PHACTR2	5504
PDGFA	5484
ECM1	5213
TGFB1	5201
ACTN4	5132
OLA1	4999
CD109	4343
RAB27B	3588
TIMP3	3463
ENDOD1	3416
ALB	3339
CHID1	2811
MANF	2532
PLEK	2120
CFD	2016
APOOL	1644
TTN	1246
TF	1172
PRKCA	1163
STX4	626
FLNA	547
TMX3	-800
PCYOX1L	-1974
PLG	-1998
CALM1	-2048
ORM2	-2594
MAGED2	-2729
ITIH3	-2982
SOD1	-4927
ITIH4	-6217
BRPF3	-6480
SERPINF2	-6601
PPIA	-6900
SELENOP	-7304
TGFB2	-7546
TGFB3	-7674
NHLRC2	-7843
VEGFB	-7866
CDC37L1	-8413
TEX264	-8472
PDGFB	-8575
A2M	-9822
FAM3C	-10007
HABP4	-10972
CTSW	-11238
SERPING1	-11444
LGALS3BP	-11611

---

Platelet degranulation

	831
set	Platelet degranulation
setSize	106
pANOVA	7.21e-16
s.dist	0.453
p.adjustANOVA	6.56e-14

Top enriched genes

GeneID	Gene Rank
F5	9524
CYB5R1	9511
CD36	9486
CLU	9423
CD63	9330
QSOX1	9302
APLP2	9296
FERMT3	9287
ALDOA	9274
ACTN1	9210
SERPINA1	9179
LHFPL2	9147
APP	9123
STXBP2	9067
ITGA2B	8942
TOR4A	8938
F13A1	8919
VTI1B	8892
HGF	8856
LAMP2	8803

Click HERE to show all gene set members

GeneID	Gene Rank
F5	9524
CYB5R1	9511
CD36	9486
CLU	9423
CD63	9330
QSOX1	9302
APLP2	9296
FERMT3	9287
ALDOA	9274
ACTN1	9210
SERPINA1	9179
LHFPL2	9147
APP	9123
STXBP2	9067
ITGA2B	8942
TOR4A	8938
F13A1	8919
VTI1B	8892
HGF	8856
LAMP2	8803
SRGN	8781
TIMP1	8594
CLEC3B	8592
TLN1	8554
SELP	8499
SYTL4	8410
ITGB3	8367
FN1	8294
EGF	8267
CFL1	8242
CAP1	8200
GAS6	8164
LY6G6F	8148
ANXA5	8122
ORM1	8082
SCCPDH	7913
CALU	7894
PROS1	7763
MMRN1	7746
PECAM1	7743
SERPINE1	7580
ABCC4	7559
TAGLN2	7451
SPARC	7411
VEGFA	7389
VCL	7380
HSPA5	7118
VEGFC	7057
WDR1	7052
F8	6996
PSAP	6909
VWF	6607
TUBA4A	6587
TMSB4X	6399
GTPBP2	6377
PPBP	6029
CD9	6004
THBS1	5946
PF4	5777
A1BG	5617
PFN1	5562
PHACTR2	5504
PDGFA	5484
ECM1	5213
TGFB1	5201
ACTN4	5132
OLA1	4999
CD109	4343
RAB27B	3588
TIMP3	3463
ENDOD1	3416
ALB	3339
CHID1	2811
MANF	2532
PLEK	2120
CFD	2016
APOOL	1644
TTN	1246
TF	1172
FLNA	547
TMX3	-800
PCYOX1L	-1974
PLG	-1998
CALM1	-2048
ORM2	-2594
MAGED2	-2729
ITIH3	-2982
SOD1	-4927
ITIH4	-6217
BRPF3	-6480
SERPINF2	-6601
PPIA	-6900
SELENOP	-7304
TGFB2	-7546
TGFB3	-7674
NHLRC2	-7843
VEGFB	-7866
CDC37L1	-8413
TEX264	-8472
PDGFB	-8575
A2M	-9822
FAM3C	-10007
HABP4	-10972
CTSW	-11238
SERPING1	-11444
LGALS3BP	-11611

---

Toll-like Receptor Cascades

	1245
set	Toll-like Receptor Cascades
setSize	143
pANOVA	3.06e-15
s.dist	0.382
p.adjustANOVA	2.61e-13

Top enriched genes

GeneID	Gene Rank
S100A12	9567
S100A9	9562
S100A8	9560
CD36	9486
ITGAM	9453
TLR8	9335
DUSP3	9324
NKIRAS2	9308
CTSB	9304
TLR5	9254
MAPK14	9219
CD14	9164
UBE2D1	9125
APP	9123
MAPK3	9078
TLR2	9069
TLR1	9041
MAP2K6	9010
TLR4	8981
MAP2K1	8960

Click HERE to show all gene set members

GeneID	Gene Rank
S100A12	9567
S100A9	9562
S100A8	9560
CD36	9486
ITGAM	9453
TLR8	9335
DUSP3	9324
NKIRAS2	9308
CTSB	9304
TLR5	9254
MAPK14	9219
CD14	9164
UBE2D1	9125
APP	9123
MAPK3	9078
TLR2	9069
TLR1	9041
MAP2K6	9010
TLR4	8981
MAP2K1	8960
IRAK3	8947
TLR6	8931
ITGB2	8908
LY96	8871
MAP2K3	8785
UBE2D3	8710
NOD2	8393
PPP2CA	8308
CTSS	8300
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959
CNPY3	7831
RPS6KA1	7800
LY86	7774
PPP2CB	7769
PELI3	7736
MAPK1	7520
TANK	7494
DNM3	7167
BTK	7156
TAB2	7070
MAP2K4	6948
NFKBIA	6835
UBB	6737
PELI1	6596
BPI	6538
TICAM1	6380
NFKB1	6367
FBXW11	6282
MAP3K8	6262
TICAM2	6244
FOS	6179
DNM2	6163
IRAK1	6159
ATF1	5790
FADD	5746
TAB1	5711
TIRAP	5700
UBE2V1	5681
TNIP2	5630
IKBKG	5434
PTPN11	5383
MAP3K1	5160
PLCG2	5103
CTSK	5077
ECSIT	4997
IKBKE	4779
BIRC2	4749
UBE2D2	4721
PPP2R1A	4669
EEA1	4631
CTSL	4583
UBC	4421
DUSP6	4367
SKP1	4349
RIPK3	4262
MAPKAPK2	4176
MAPK10	4136
UNC93B1	4133
JUN	3964
MAPK11	3955
SOCS1	3886
DNM1	3526
RPS6KA2	3177
TAB3	3165
TBK1	3159
RPS6KA3	3012
MAP3K7	2453
PPP2R5D	2440
ATF2	2110
HSP90B1	2086
UBE2N	1951
MAP2K7	1647
PIK3C3	1626
AGER	1309
VRK3	1293
UBA52	1071
RIPK2	1042
ELK1	1040
NKIRAS1	387
NFKBIB	-88
HMGB1	-200
TRAF6	-241
PPP2R1B	-246
MEF2C	-319
TLR7	-655
CD180	-761
NFKB2	-865
MAPK7	-1294
CREB1	-1382
RELA	-1807
CTSV	-2816
TLR10	-2899
DUSP7	-3253
PIK3R4	-4040
RBSN	-4574
LGMN	-4724
BTRC	-4932
S100B	-5025
IKBKB	-5290
TRAF3	-5296
TLR9	-5909
DUSP4	-6432
RPS27A	-6894
MAPK9	-7182
S100A1	-8267
IRF3	-8479
IRF7	-8889
MAPK8	-9646
IRAK2	-9718
SIGIRR	-10688
BIRC3	-10830
RIPK1	-11184
CASP8	-11463
CUL1	-11467
TLR3	-11538
RPS6KA5	-11616
SARM1	-11973
PTPN4	-12133
NOD1	-12234

---

Asparagine N-linked glycosylation

	86
set	Asparagine N-linked glycosylation
setSize	269
pANOVA	8.72e-15
s.dist	0.275
p.adjustANOVA	6.99e-13

Top enriched genes

GeneID	Gene Rank
CTSA	9555
NPL	9548
ASGR2	9541
F5	9524
ST6GALNAC3	9271
SPTB	9250
ARF4	9201
ASGR1	9191
SERPINA1	9179
KDELR1	9163
DCTN2	9158
CD55	9157
NEU1	9084
ARF1	9083
RAB1A	9075
TGFA	9031
CTSZ	9001
RAD23B	8926
B4GALT5	8909
ANK1	8897

Click HERE to show all gene set members

GeneID	Gene Rank
CTSA	9555
NPL	9548
ASGR2	9541
F5	9524
ST6GALNAC3	9271
SPTB	9250
ARF4	9201
ASGR1	9191
SERPINA1	9179
KDELR1	9163
DCTN2	9158
CD55	9157
NEU1	9084
ARF1	9083
RAB1A	9075
TGFA	9031
CTSZ	9001
RAD23B	8926
B4GALT5	8909
ANK1	8897
OS9	8845
NSF	8815
CMAS	8802
ST3GAL2	8782
EDEM2	8778
MGAT4B	8742
GLB1	8652
EDEM3	8573
CAPZA2	8521
RAB1B	8407
DCTN4	8385
COPA	8319
ST8SIA4	8264
CAPZA1	8165
SEC24D	8130
CAPZB	8057
RPN1	8009
MAN1A1	7979
ARF5	7975
COPB2	7965
NANS	7936
TMED7	7909
NUS1	7900
TRAPPC1	7887
CNIH1	7832
ARF3	7798
MPDU1	7794
SPTA1	7785
SEC24A	7716
ACTR10	7652
COPG2	7636
DYNC1I2	7629
KDELR2	7585
COPG1	7533
FUCA1	7508
AMFR	7452
SEC23A	7416
COPB1	7399
DCTN6	7382
FPGT	7374
SLC35A1	7309
TFG	7240
TMED9	7199
STX5	7186
LMAN2	7178
TRAPPC3	7158
MCFD2	7136
RPN2	7135
PSMC1	7096
ACTR1A	7088
LMAN2L	7003
F8	6996
DYNC1LI1	6992
COPE	6979
DDOST	6972
VCP	6955
PPP6C	6887
SEL1L	6834
ST6GALNAC2	6828
UBB	6737
ST3GAL6	6671
GORASP1	6670
MAN2A2	6669
RENBP	6608
RNF185	6584
SAR1B	6562
PREB	6450
CALR	6415
COL7A1	6375
TSTA3	6326
GOLGA2	6217
MGAT1	6190
TMED2	6098
DCTN3	6080
DYNLL1	6049
CHST8	6024
DAD1	5994
CD59	5964
SEC22B	5939
ST3GAL4	5930
ALG14	5825
SEC13	5820
ARCN1	5661
MIA2	5618
TMEM115	5605
CANX	5526
AREG	5494
TRAPPC9	5414
PPP6R1	5328
PRKCSH	5300
YKT6	5277
TRAPPC5	5253
DCTN1	5143
UGGT1	5125
SLC17A5	5092
GMDS	4987
DPM2	4786
UGGT2	4756
SEC16A	4687
UBC	4421
RFT1	4358
B4GALT1	4354
COG7	4321
DYNC1LI2	4253
PMM1	4217
DYNC1I1	4211
TRAPPC6B	4201
USO1	4192
NAPG	4190
PDIA3	4172
STT3A	4129
SRD5A3	4089
COPZ1	4081
GMPPA	3925
ARFGAP3	3807
SEC24B	3655
SCFD1	3593
PPP6R3	3323
NAGK	3197
DERL2	3093
DOLPP1	2886
TMED3	2779
SLC35C1	2739
MAGT1	2698
RNF139	2697
ALG12	2650
DPM3	2581
CTSC	2547
CSNK1D	2412
MLEC	2315
DPAGT1	2191
FCSK	1937
UBXN1	1884
ST8SIA5	1677
MGAT2	1670
ALG6	1645
DPM1	1591
PMM2	1425
NAPA	1385
SEC31A	1144
B4GALNT2	1082
UBA52	1071
SYVN1	997
CNIH2	727
B4GALT4	587
ST3GAL3	485
SEC16B	351
TMED10	328
COG4	15
TBC1D20	-49
EDEM1	-133
GOSR1	-160
COG8	-406
SEC23IP	-469
BET1	-631
MANEA	-658
ALG5	-694
PGM3	-773
ST6GALNAC4	-827
GANAB	-1004
ALG3	-1284
MAN2A1	-1350
ALG2	-1381
ST6GAL2	-1456
GOSR2	-1504
ARFGAP1	-1962
MAN1A2	-2017
DHDDS	-2090
MGAT4C	-2101
KDELR3	-2154
MGAT3	-2157
TRIM13	-2320
TRAPPC2L	-2337
SEC24C	-2615
NAPB	-2763
MOGS	-3075
MGAT5	-3137
COG5	-3318
SPTBN5	-3449
ALG11	-3638
MARCHF6	-3663
ALG8	-3682
DOLK	-3691
NGLY1	-3744
NEU3	-3800
DYNLL2	-4042
DCTN5	-4140
SEC22C	-4285
GBF1	-4322
RNF103	-4584
MAN1B1	-4926
ANK3	-4974
SEC22A	-5080
ST6GALNAC1	-5118
SPTBN2	-5189
FUOM	-5217
COG3	-5230
GNE	-5250
GOLGB1	-5425
MGAT4A	-5545
ARFGAP2	-5850
COG6	-5872
MVD	-5926
B4GALT2	-6126
NUDT14	-6189
ANKRD28	-6311
MIA3	-6330
MAN1C1	-6459
RNF5	-6497
GFPT1	-6551
TRAPPC4	-6836
RPS27A	-6894
ENGASE	-6927
GMPPB	-7145
BET1L	-7385
SPTBN1	-7419
ST3GAL1	-7452
ALG13	-7736
DYNC1H1	-7822
ALG10	-7908
ST8SIA1	-7927
COG2	-8023
ALG10B	-8085
TRAPPC2	-8851
ALG1	-8949
B4GALT6	-8981
DERL1	-9113
CNIH3	-9196
TRAPPC10	-9516
GNPNAT1	-9605
NANP	-9677
FUT8	-9752
ALG9	-9826
GFPT2	-9963
MPI	-10185
B4GALT3	-10619
AMDHD2	-10643
LMAN1	-10699
TRAPPC6A	-10921
STX17	-11009
COPZ2	-11047
SPTAN1	-11438
ST8SIA6	-11578
ST3GAL5	-11628
CHST10	-11858
ST6GAL1	-11887
ST6GALNAC6	-11958
COG1	-12057
UAP1	-12160

---

Disease

	284
set	Disease
setSize	1303
pANOVA	1.03e-14
s.dist	0.127
p.adjustANOVA	7.8e-13

Top enriched genes

GeneID	Gene Rank
CSF2RA	9574
ADAMTS2	9573
WASF1	9568
CYP19A1	9565
FZD5	9561
CYP1B1	9556
CTSA	9555
IDH1	9547
VCAN	9538
F12	9535
HRH2	9509
TALDO1	9505
GGT1	9495
CD163	9493
CD36	9486
SLC1A3	9482
ADM	9454
PRKACA	9441
GNG10	9436
GPR27	9426

Click HERE to show all gene set members

GeneID	Gene Rank
CSF2RA	9574.0
ADAMTS2	9573.0
WASF1	9568.0
CYP19A1	9565.0
FZD5	9561.0
CYP1B1	9556.0
CTSA	9555.0
IDH1	9547.0
VCAN	9538.0
F12	9535.0
HRH2	9509.0
TALDO1	9505.0
GGT1	9495.0
CD163	9493.0
CD36	9486.0
SLC1A3	9482.0
ADM	9454.0
PRKACA	9441.0
GNG10	9436.0
GPR27	9426.0
OPLAH	9409.0
FCGR1A	9397.0
LMNB1	9391.0
IL10	9385.0
TPST1	9377.0
H2BC21	9368.0
IMPDH1	9364.0
AP1S1	9338.0
MAOA	9325.0
PC	9322.0
GRB2	9320.0
GNS	9309.0
ARPC1B	9303.0
GPR84	9292.0
ST6GALNAC3	9271.0
CYFIP1	9270.0
KREMEN1	9259.0
TLR5	9254.0
MAPK14	9219.0
BSG	9214.0
SLC4A1	9198.0
GUCY2C	9182.0
H2BC12	9178.0
CD14	9164.0
FURIN	9162.0
GYG1	9141.0
NCSTN	9139.0
UBE2D1	9125.0
APP	9123.0
ADCY3	9101.0
SYK	9087.0
NEU1	9084.0
ARF1	9083.0
MAPK3	9078.0
TLR2	9069.0
FKBP1A	9066.0
PIK3CB	9065.0
ACTB	9060.0
HDAC4	9057.0
CLTC	9056.0
TLR1	9041.0
PAPSS1	9039.0
ANAPC15	9035.0
TGFA	9031.0
IL1R1	9030.0
KL	9019.0
MAP2K6	9010.0
YWHAE	9009.0
HK1	9004.0
HCK	8992.0
AGTRAP	8987.0
TLR4	8981.0
MAML3	8965.0
MAP2K1	8960.0
QKI	8951.0
ITGA2B	8942.0
CRK	8941.0
MYO10	8933.0
TLR6	8931.0
ARPC1A	8923.0
GALK1	8913.0
CUX1	8905.0
ERLIN2	8899.0
ENO1	8877.0
NUP58	8872.0
LY96	8871.0
GNG5	8866.0
CHMP2A	8863.0
GCKR	8862.0
FCGR2A	8858.0
HGF	8856.0
APBB1IP	8849.0
OS9	8845.0
CHMP4B	8830.0
CEBPD	8826.0
NLRP3	8813.0
ERLIN1	8806.0
E2F2	8791.0
MAP2K3	8785.0
ST3GAL2	8782.0
UBAP1	8779.0
RAB7A	8775.0
MARK3	8774.0
TCN2	8759.0
HEXB	8749.0
RBPJ	8744.0
AP1B1	8741.0
PYCARD	8734.0
FOXO3	8729.0
RAC1	8720.0
ADAM10	8705.0
PGK1	8681.0
TBXAS1	8676.0
AP2M1	8673.0
ACTG1	8671.0
CDK5	8663.0
JAG1	8661.0
ARPC5	8653.0
GLB1	8652.0
ADAMTS3	8650.0
RB1	8649.0
PRKAR1A	8616.0
CAPN1	8613.0
WAS	8596.0
MEFV	8576.0
TLN1	8554.0
RHOG	8544.0
PSMB7	8535.0
ARRB2	8517.0
PTEN	8516.0
ADORA2B	8515.0
TFDP1	8500.0
PSMD4	8498.0
DNAJC3	8468.0
TXN	8414.0
CLTA	8402.0
FGR	8397.0
BAG4	8384.0
AP3B1	8377.0
WASF2	8373.0
ENTPD1	8372.0
ITGB3	8367.0
CHMP3	8339.0
JAK3	8337.0
PSME3	8331.0
IRS2	8323.0
ARPC3	8309.0
PPP2CA	8308.0
TXNRD1	8303.0
FN1	8294.0
GNB1	8278.0
EGF	8267.0
COMT	8260.0
TRIM27	8257.0
GBE1	8237.0
GNB2	8234.0
IL6R	8229.0
PAK2	8226.0
SLC12A6	8216.0
C1GALT1C1	8215.0
CHSY1	8210.0
IQGAP1	8189.0
PSMB5	8188.0
HSPA1A	8178.0
H2BC5	8163.0
STAT3	8152.0
PTPN12	8125.0
ATP6V1H	8119.0
GAB2	8100.0
MAP1LC3B	8099.0
GNAI2	8094.0
MYD88	8091.0
AP2S1	8080.0
TAF12	8078.0
H2BC11	8076.0
H2AC6	8070.0
C3AR1	8067.0
ATG7	8065.0
CAST	8045.0
PRKAR1B	8040.0
GAA	8031.0
GNAI3	8027.0
VAV1	8021.0
GNAS	8019.0
NUP214	8011.0
NOTCH3	8004.0
RAF1	7991.0
TBL1X	7984.0
ADAM17	7980.0
VPS37C	7973.0
NEDD4L	7972.0
CHUK	7959.0
NCOR2	7948.0
PSTPIP1	7930.0
FGFR1OP2	7920.0
AKT1S1	7902.0
NUS1	7900.0
ACTR3	7888.0
PSMD6	7881.0
TSG101	7856.0
PSEN1	7843.0
PIK3AP1	7836.0
ACTR2	7827.0
CSNK1A1	7813.0
GSK3A	7811.0
MPDU1	7794.0
SLC40A1	7793.0
CASP9	7784.0
PPP2CB	7769.0
CSF2RB	7764.0
P2RX4	7740.0
SH3GL1	7733.0
LYN	7728.0
SLC24A4	7713.0
PSMD9	7712.0
MAP3K11	7707.0
VPS25	7696.0
H2AC11	7674.0
POLR2E	7660.0
ELOC	7637.0
DOCK2	7631.0
DYNC1I2	7629.0
HNRNPK	7619.0
GP1BB	7606.0
ARPC4	7605.0
CAPNS1	7603.0
CBL	7599.0
GP9	7589.0
ELOB	7586.0
NCKAP1	7562.0
H2BC4	7549.0
CDC42	7539.0
MAPK1	7520.0
NCKAP1L	7516.0
CCND3	7510.0
H2BC17	7502.0
ADAMTSL4	7487.0
PSMD2	7470.0
GUSB	7454.0
ARPC2	7449.0
ROCK1	7445.0
ANTXR2	7435.0
MVB12A	7425.0
DOCK1	7413.0
IL18	7395.0
VEGFA	7389.0
VCL	7380.0
ARSB	7373.0
ELOA	7366.0
SHOC2	7365.0
AP2A2	7360.0
IL1RAP	7349.0
PSMA1	7346.0
TAF13	7332.0
ABCD1	7330.0
SLC9A9	7329.0
BCL2L11	7326.0
RAP1A	7319.0
SLC35A1	7309.0
RPL26L1	7295.0
PSMD1	7283.0
PSMB3	7265.0
CFP	7228.0
RXFP2	7217.0
GYS1	7212.0
GTF2A2	7207.0
TYK2	7192.0
TAF10	7190.0
GALNS	7183.0
PSMA7	7174.0
RAB5A	7166.0
BTK	7156.0
ABI1	7154.0
GNB4	7138.0
PRDX1	7104.0
PSMC1	7096.0
PPP1CB	7093.0
BRK1	7085.0
SLC7A7	7038.0
SLC22A5	7020.0
STAT5B	7011.0
BAD	7002.0
F8	6996.0
DYNC1LI1	6992.0
STAT5A	6983.0
SUMO1	6973.0
VCP	6955.0
CYBA	6952.0
MAP2K4	6948.0
PSMB6	6927.0
KDM7A	6926.0
EXT1	6923.0
SPRED2	6917.0
WASF3	6915.0
MAP2K2	6906.0
PPP2R5B	6870.0
UBE2E1	6853.0
SLC2A9	6839.0
NFKBIA	6835.0
SEL1L	6834.0
ST6GALNAC2	6828.0
PRKAR2B	6824.0
XRCC4	6793.0
AP1M1	6788.0
H3C15	6780.5
MYH9	6772.0
POLR2J	6769.0
E2F3	6744.0
UBB	6737.0
PSMF1	6724.0
GSK3B	6720.0
PSMC6	6701.0
MYO5A	6685.0
INSL3	6681.0
SDC4	6673.0
AP2A1	6628.0
LMBRD1	6613.0
GNG11	6612.0
VWF	6607.0
MUC1	6589.0
PDCD6IP	6585.0
RNF185	6584.0
VPS37A	6560.0
PSMD12	6537.0
GALNT1	6518.0
FOXO4	6493.0
MYO9B	6481.0
AHCYL1	6475.0
E2F1	6473.0
CTNNB1	6463.0
RLN3	6445.0
MMADHC	6435.0
ABCB6	6425.0
BECN1	6423.0
CALR	6415.0
H2BC18	6400.0
YWHAB	6398.0
TICAM1	6380.0
NFKB1	6367.0
SLC25A6	6340.0
PPP1CC	6334.0
ELMO1	6324.0
GP1BA	6320.0
PSMD11	6296.0
CTDP1	6295.0
AGGF1	6284.0
PRKAR2A	6265.0
ANAPC11	6249.0
APH1B	6248.0
VTA1	6232.0
SH3KBP1	6227.0
GOLGA2	6217.0
PDPK1	6209.0
EP300	6208.0
MGAT1	6190.0
STAM2	6183.0
LTF	6182.0
ROCK2	6151.0
LRRFIP1	6127.0
PIK3CD	6096.0
HDAC7	6070.0
ABCA1	6066.0
DYNLL1	6049.0
PSMD7	6017.0
CD9	6004.0
PDGFRA	6002.0
PSMD13	5991.0
SNF8	5990.0
PPP2R5A	5985.0
SGSH	5984.0
NCOR1	5979.0
PSMA6	5978.0
BRD4	5959.0
PGM1	5947.0
THBS1	5946.0
ADM2	5935.0
ST3GAL4	5930.0
ITPR2	5919.0
MSH3	5882.0
TPST2	5872.0
GTF2E2	5856.0
PSMD8	5845.0
CHMP1A	5834.0
PSENEN	5833.0
ALG14	5825.0
SEC13	5820.0
BIN2	5796.0
WIPF2	5769.0
DVL3	5734.0
GAB1	5723.0
CHMP2B	5713.0
TIRAP	5700.0
G6PC	5665.0
ABCC6	5598.0
CHMP6	5590.0
HDAC2	5569.0
GCLM	5558.0
CANX	5526.0
GTF2F2	5503.0
RPS9	5496.0
AREG	5494.0
PDGFA	5484.0
H2BC9	5461.0
H2BC15	5458.0
XRCC5	5452.0
MAML1	5447.0
IKBKG	5434.0
PSMA2	5433.0
NRAS	5411.0
ACACA	5394.0
LIG4	5391.0
FXR1	5385.0
PTPN11	5383.0
POLR2L	5362.0
BRAP	5352.0
GGCX	5306.0
PRKCSH	5300.0
CDK7	5292.0
CSK	5285.0
VPS4B	5279.0
NOTCH2	5276.0
SDC2	5257.0
SNW1	5255.0
SLC29A3	5252.0
MVB12B	5251.0
RAC2	5238.0
GRSF1	5232.0
ADCY4	5226.0
CTSG	5224.0
ETV6	5219.0
CORO1A	5206.0
TGFB1	5201.0
CALCRL	5199.0
SLC3A2	5197.0
CCNE2	5178.0
UBE2C	5168.0
SYT1	5162.0
RAE1	5152.0
GALE	5138.0
MAPKAP1	5130.0
PLCG2	5103.0
SLC17A5	5092.0
KPNA4	5074.0
TRAK1	5063.0
ELL	5057.0
PIK3R2	5051.0
GTF2F1	5042.0
H2AC20	5039.0
FAM114A2	5026.0
CDC25C	5024.0
VAV3	4974.0
CHMP5	4954.0
SMAD2	4939.0
HBEGF	4878.0
SLC9A6	4834.0
IL1B	4830.0
UBE2S	4810.0
FDXR	4803.0
HDAC11	4790.0
DPM2	4786.0
CBX1	4763.0
HDAC5	4761.0
HDAC3	4734.0
NOTCH1	4733.0
PIK3CA	4697.0
PSMD3	4693.0
PPP2R1A	4669.0
POLR2F	4646.0
TBL1XR1	4627.0
CTSL	4583.0
HGS	4570.0
NUP50	4544.0
RPL3L	4539.0
SLC39A4	4520.0
SLC16A1	4517.0
ELMO2	4507.0
PTK2	4506.0
SOD2	4458.0
CDKN1A	4438.0
SEM1	4436.0
UBC	4421.0
TPMT	4406.0
NMT1	4400.0
DUSP6	4367.0
RFT1	4358.0
B4GALT1	4354.0
SKP1	4349.0
GNG8	4339.0
PARP4	4298.0
HYAL1	4297.0
DYNC1LI2	4253.0
VPS28	4247.0
LRP5	4241.0
DYNC1I1	4211.0
RHBDF2	4205.0
APH1A	4198.0
EPS15	4189.0
MDM2	4179.0
SHC1	4173.0
CTBP2	4142.0
SLC22A18	4137.0
UNC93B1	4133.0
CDC37	4125.0
KSR1	4113.0
PSMB2	4103.0
SRD5A3	4089.0
CASP1	4086.0
AP1G1	4052.0
RBX1	4039.0
NRG1	4018.0
PDZD3	4007.0
SSPO	3985.0
JUN	3964.0
G6PC3	3956.0
VPS37B	3933.0
NELFE	3922.0
CYP27A1	3913.0
SND1	3911.0
TGFBR2	3881.0
GTF2H5	3879.0
LMNA	3863.0
MMUT	3861.0
TRIM24	3824.0
KRAS	3760.0
STRN	3758.0
VHL	3742.0
KIAA1549	3668.0
FGF2	3660.0
AKT1	3656.0
GTF2B	3599.0
POLR2G	3581.0
ERCC2	3545.0
PSMD5	3507.0
PRDX2	3467.0
CREBBP	3460.0
RLBP1	3457.0
PSMB1	3422.0
P2RX7	3420.0
ZMYM2	3405.0
GNAI1	3364.0
MYO1C	3351.0
RAP1B	3331.0
SLC35A2	3310.0
APC	3284.0
ADORA2A	3227.0
MRC1	3187.0
TBK1	3159.0
NUP37	3153.0
HDAC8	3141.0
NUP98	3124.0
AVPR1A	3123.0
NF1	3113.0
ABCG8	3112.0
DERL2	3093.0
GTF2H2	3035.0
RNGTT	3030.0
CDC26	3013.0
SUPT4H1	3005.0
POMC	2971.0
CDC25A	2948.0
CCNK	2936.0
GNAZ	2927.0
ATP1A1	2849.0
SLC12A1	2813.0
RAMP3	2787.0
GTF2A1	2744.0
SLC35C1	2739.0
CFTR	2738.0
SEMA5B	2735.0
PSMD14	2703.0
PSMC2	2696.0
ARAF	2680.0
ALG12	2650.0
JAK2	2599.0
DPM3	2581.0
EPGN	2579.0
PSMB4	2552.0
SDC3	2535.0
SLC27A4	2527.0
KPNB1	2491.0
CHMP4A	2480.0
PPP2R5D	2440.0
MYC	2367.0
GTF2E1	2363.0
HDAC10	2302.0
SFPQ	2294.0
CLCN6	2278.0
DPAGT1	2191.0
RPS27L	2117.0
ARRB1	2098.0
TSHR	2057.0
PSMC3	2018.0
MTRR	2007.0
GALNT3	2006.0
TAF7	1986.0
FDX1	1928.0
EREG	1906.0
CAMK2G	1888.0
CCNC	1883.0
HGSNAT	1871.0
IRS1	1806.0
SFTPB	1764.0
AP1M2	1740.0
UGT1A1	1739.0
RCC1	1712.0
MGAT2	1670.0
MAP2K7	1647.0
PSMD10	1646.0
ALG6	1645.0
TGFBR1	1642.0
PIK3C3	1626.0
DPM1	1591.0
SUGT1	1576.0
POLR2C	1531.0
RPIA	1455.0
PTGER2	1451.0
PMM2	1425.0
NEIL3	1349.0
HSP90AA1	1348.0
HDAC9	1347.0
KPNA1	1320.0
BRAF	1314.0
SLC34A2	1301.0
STAM	1299.0
GP5	1281.0
HEXA	1274.0
TAF9	1249.0
GCK	1242.0
CHST14	1177.0
UBA52	1071.0
CAPN2	1058.0
ELK1	1040.0
SYVN1	997.0
FMOD	991.0
KPNA3	958.0
GNG3	894.0
SLC25A5	892.0
CUL5	847.0
ADAMTSL3	838.0
LRP6	787.0
CCNH	783.0
VPS4A	776.0
ERLEC1	775.0
NUP62	772.0
SLC7A9	708.0
GSS	697.0
ZCRB1	691.0
IGHV1-2	679.0
RPS6KB2	652.0
POMT2	607.0
RDH5	602.0
NR3C1	600.0
WIPF1	581.0
ST3GAL3	485.0
GNB5	467.0
SYT2	451.0
AHCY	449.0
HDAC1	394.0
NELFB	385.0
AKT2	345.0
KREMEN2	321.0
NCKIPSD	320.0
POLR2I	316.0
AVPR2	306.0
MLST8	304.0
EEF2	289.0
WASL	283.0
SLC11A2	243.0
ABL1	229.0
IGHV2-5	174.0
ADCY9	146.0
IGHV3-53	122.0
RPL36AL	91.0
HMGA1	81.0
DVL1	61.0
IGLC3	-37.0
ITGB1	-50.0
RPLP1	-65.0
CD86	-71.0
CXCR4	-125.0
IGKV1-39	-173.0
BAIAP2	-179.0
RPS4Y1	-222.0
PPP2R1B	-246.0
RPS24	-282.0
DCXR	-311.0
FMO3	-352.0
IGKV5-2	-357.0
FAU	-402.0
IGLV5-45	-419.0
IGHV3-7	-437.0
IGKV3-11	-446.0
ERBB3	-468.0
MAML2	-476.0
TNKS2	-512.0
PABPN1	-526.0
PSMA4	-538.0
IGHV3-48	-583.0
ERBIN	-585.0
PPP2R5E	-627.0
TLR7	-655.0
CDC27	-659.0
GGT5	-679.0
GPR83	-685.0
IGLV2-8	-740.0
UBE2I	-746.0
TSC2	-804.0
RANBP2	-808.0
IGHV1-46	-823.0
ST6GALNAC4	-827.0
FAM131B	-831.0
NFKB2	-865.0
C1QBP	-902.0
GPS2	-914.0
PSMC5	-948.0
TCEA1	-951.0
IGKV1-5	-984.0
IGKV1-16	-990.0
GANAB	-1004.0
RPL15	-1017.0
IGHV3-23	-1042.0
RPLP0	-1054.0
CDK5R1	-1166.0
IGKV1D-39	-1172.0
XPO1	-1199.0
SLC36A2	-1224.0
RPL8	-1242.0
ALG3	-1284.0
IGKV2D-28	-1291.0
IGLV7-46	-1341.0
ALG2	-1381.0
CREB1	-1382.0
IGLV10-54	-1414.0
EXT2	-1435.0
IGHV3-13	-1436.0
RPS26	-1443.0
RPL28	-1469.0
IGLV2-18	-1472.0
DUSP10	-1587.0
CP	-1599.0
IGKV1-33	-1613.0
RPL22L1	-1643.0
IGLV1-36	-1670.0
SV2B	-1692.0
SLC34A1	-1698.0
IGKV2-30	-1725.0
TAF4	-1726.0
PRELP	-1742.0
ADCY6	-1746.0
RPS13	-1759.0
IGLV4-69	-1768.0
POLR2K	-1792.0
RELA	-1807.0
IGHV1-69	-1811.0
TAF3	-1820.0
RPL9	-1827.0
RBBP4	-1907.0
NRG4	-1939.0
IGHV4-59	-1969.0
ABCC2	-1990.0
CDK8	-1997.0
VPS33B	-2000.0
IGLV3-19	-2016.0
RPL7	-2018.0
IGKV3-15	-2034.0
IGHV3-11	-2041.0
CALM1	-2048.0
IGHV4-34	-2080.0
DHDDS	-2090.0
PAPSS2	-2099.0
RPS8	-2138.0
SLC33A1	-2159.0
ANAPC16	-2165.0
GNG4	-2175.0
MSH6	-2199.0
IGHV3-30	-2221.0
GTF2H3	-2247.0
FZR1	-2253.0
MUCL1	-2297.0
AP1S2	-2330.0
KAT2B	-2393.0
SUZ12	-2444.0
HTR7	-2465.0
ALDOB	-2466.0
POLR2B	-2536.0
HLA-A	-2578.0
IGLV2-23	-2597.0
TAF9B	-2602.0
IDS	-2609.0
MUC4	-2624.0
IGKV4-1	-2625.0
NEURL1B	-2658.0
AP2B1	-2748.0
DPEP2	-2760.0
PLK2	-2772.0
GNB3	-2776.0
IGLV2-11	-2782.0
IGKV1-17	-2799.0
POLR2H	-2817.0
IGKV3-20	-2824.0
ADCY2	-2874.0
IGLV6-57	-2876.0
FGFR4	-2892.0
TAF11	-2897.0
TLR10	-2899.0
GTF2H4	-2906.0
GTF2H1	-2929.0
SLC26A2	-2930.0
RPL27	-2934.0
STX1B	-2970.0
DPEP3	-2980.0
IGHV3-33	-2989.0
MIB1	-2999.0
MUC6	-3012.0
B3GAT3	-3020.0
SV2C	-3038.0
RPL39	-3047.0
PHB	-3050.0
MOGS	-3075.0
IGLV1-44	-3076.0
NUP85	-3077.0
PSMB8	-3080.0
POLR2A	-3105.0
IGHV2-70	-3195.0
DUSP7	-3253.0
MUC16	-3285.0
ADCY7	-3307.0
HRAS	-3335.0
ADAMTS5	-3336.0
RPL23	-3352.0
CYP24A1	-3354.0
KSR2	-3364.0
RPL6	-3382.0
IGHG3	-3394.0
CYP27B1	-3407.0
FRS2	-3430.0
RPL13	-3461.0
THSD4	-3568.0
RPL4	-3592.0
RPL29	-3604.0
GPC2	-3613.0
ALG11	-3638.0
AMN	-3675.0
ALG8	-3682.0
DOLK	-3691.0
RPS15	-3698.0
RPL7A	-3699.0
ADAMTS17	-3723.0
IGHV4-39	-3735.0
CD19	-3769.0
NELFA	-3858.0
KANK1	-3909.0
MYO18A	-3939.0
CDK9	-3988.0
FGF7	-3999.0
RPL37A	-4004.0
IGKV3D-20	-4012.0
PIK3R4	-4040.0
DYNLL2	-4042.0
KCNJ11	-4054.0
POLR2D	-4058.0
STX1A	-4061.0
GOLGA4	-4063.0
VAV2	-4073.0
IGLV3-1	-4093.0
IGLV7-43	-4100.0
IGLV1-40	-4105.0
RPS21	-4115.0
IGKC	-4212.0
ADAMTS13	-4230.0
IGLV3-25	-4239.0
C1GALT1	-4318.0
CYP7B1	-4321.0
HTR6	-4345.0
CHST6	-4380.0
IGLV1-51	-4413.0
IGLV3-21	-4455.0
TAF5	-4458.0
XRCC6	-4475.0
CNKSR2	-4481.0
RPL31	-4507.0
RPS2	-4509.0
CSPG4	-4511.0
B3GALT6	-4549.0
RPS16	-4570.0
MUC5B	-4618.0
RPL5	-4631.0
ACY1	-4646.0
RPS28	-4647.0
PARP9	-4658.0
SLC5A2	-4689.0
GPC1	-4697.0
RPS3A	-4702.0
GPC4	-4718.0
RPL22	-4738.0
IGLC7	-4779.0
MAMLD1	-4791.0
ABCC9	-4801.0
NAGLU	-4826.0
FDX2	-4838.0
BANF1	-4839.0
TRIM28	-4905.0
MAN1B1	-4926.0
BTRC	-4932.0
NT5E	-4939.0
PARP6	-4956.0
CRHR2	-4975.0
RPS7	-5016.0
CDK2	-5018.0
GNG7	-5049.0
RPL18	-5054.0
ABCB4	-5056.0
AKAP9	-5065.0
ANAPC10	-5074.0
CCNT2	-5173.0
NOTCH4	-5200.0
IGKV1-12	-5223.0
SLC6A20	-5246.0
GNE	-5250.0
ANAPC7	-5259.0
RPL36	-5287.0
IKBKB	-5290.0
TRAF3	-5296.0
CDKN2A	-5302.0
PSMA3	-5314.0
SLC5A5	-5315.0
CD4	-5320.0
FGFR1	-5335.0
IGLC2	-5370.0
IGLV8-61	-5395.0
TCF7L2	-5419.0
RPL17	-5464.0
RPS5	-5478.0
RPS14	-5485.0
NOXA1	-5532.0
SLC2A10	-5543.0
IGLC1	-5548.0
PMS2	-5588.0
AP1S3	-5592.0
NHLRC1	-5613.0
NUP42	-5622.0
IGHG1	-5669.0
RPS10	-5686.0
B4GAT1	-5693.0
RPS15A	-5695.0
SOS1	-5714.0
PSMB10	-5768.0
IGKV2-28	-5778.0
MUC20	-5791.0
IGLV1-47	-5810.0
IDUA	-5812.0
RPS3	-5833.0
MRAS	-5840.0
LARGE1	-5864.0
NCBP1	-5866.0
RPL24	-5882.0
RPL38	-5890.0
TLR9	-5909.0
IGLV3-27	-5935.0
SEH1L	-5957.0
CPSF6	-5963.0
RPS4X	-5969.0
RPS12	-5985.0
TAF2	-5999.0
RPL18A	-6029.0
CDC16	-6037.0
DUT	-6053.0
RPL35A	-6080.0
PSME4	-6099.0
RPS6	-6100.0
VIPR1	-6107.0
SLC37A4	-6111.0
PSMA5	-6154.0
RPSA	-6219.0
RPS17	-6223.0
CRBN	-6236.0
RPL19	-6242.0
RPS25	-6246.0
ENTPD5	-6256.0
RPL11	-6275.0
RPS23	-6279.0
NELFCD	-6291.0
RPL27A	-6321.0
NUP153	-6325.0
CDK6	-6379.0
FZD6	-6395.0
RPL37	-6401.0
FOXO6	-6467.0
RPL21	-6481.0
FZD7	-6496.0
RNF5	-6497.0
ADAMTS14	-6509.0
RPL14	-6518.0
H2BU1	-6519.0
TAF15	-6541.0
CTBP1	-6549.0
GFPT1	-6551.0
RPL10	-6562.0
RPL32	-6577.0
RPL26	-6636.0
RPL10A	-6644.0
DUSP16	-6652.0
GPR15	-6674.0
MMACHC	-6681.0
HSP90AB1	-6702.0
FBXW7	-6709.0
IGHG4	-6718.0
SUPT5H	-6744.0
CUBN	-6752.0
NR4A1	-6762.0
ADAMTS6	-6772.0
CNTRL	-6773.0
ANAPC4	-6780.0
FGFR1OP	-6804.0
RPL34	-6807.0
SLC35D1	-6818.0
CD80	-6837.0
FGF23	-6840.0
KPNA2	-6845.0
CCND1	-6847.0
CNKSR1	-6858.0
RAN	-6874.0
RPL41	-6877.0
MLH1	-6878.0
RPS27A	-6894.0
PPIA	-6900.0
RPLP2	-6915.0
VPS36	-6942.0
PDCD1	-6963.0
SPRED3	-6979.0
NAPEPLD	-6983.0
RPL30	-6995.0
B2M	-7019.0
RPS19	-7037.0
RPL12	-7038.0
TRAT1	-7043.0
DERL3	-7065.0
TUBB	-7078.0
IGHG2	-7087.0
TPR	-7100.0
RPS11	-7122.0
KHK	-7171.0
BCR	-7186.0
FZD8	-7237.0
GPBAR1	-7268.0
SLC34A3	-7270.0
ANAPC2	-7284.0
POM121C	-7305.0
B4GALT7	-7370.0
TAF6	-7402.0
THSD1	-7421.0
RPL36A	-7442.0
ST3GAL1	-7452.0
IGLV3-12	-7472.0
DAG1	-7502.0
ITPR1	-7553.0
PSMA8	-7559.0
CD8B	-7599.0
RPS18	-7641.0
VAMP1	-7646.0
SIGMAR1	-7681.0
ZFYVE9	-7706.0
HSPG2	-7708.0
ERCC3	-7721.0
HES1	-7731.0
ALG13	-7736.0
RPS29	-7794.0
ADAMTSL5	-7800.0
CYSLTR1	-7801.0
ADRB1	-7803.0
GNG2	-7809.0
DYNC1H1	-7822.0
NUP133	-7839.0
PSEN2	-7844.0
TAF4B	-7865.0
OGG1	-7905.0
RLN2	-7910.0
PCCB	-8040.0
FIP1L1	-8076.0
RPL13A	-8123.0
NTHL1	-8143.0
SBSPON	-8155.0
RPL35	-8239.0
NEIL1	-8261.0
POM121	-8263.0
SMAD4	-8273.0
RAMP1	-8282.0
CDKN1B	-8305.0
SKP2	-8307.0
ADCY5	-8315.0
CHMP7	-8325.0
AAAS	-8337.0
HDAC6	-8348.0
THSD7A	-8381.0
PACS1	-8402.0
PARP10	-8407.0
SLC3A1	-8414.0
IGLV2-14	-8416.0
ABCD4	-8442.0
RPL3	-8478.0
LFNG	-8502.0
CTNND1	-8519.0
NUP54	-8521.0
PARP8	-8523.0
ADAMTS16	-8527.0
TAF1	-8536.0
PDGFB	-8575.0
POMT1	-8604.0
SPRED1	-8664.0
CBLL1	-8668.0
FGF22	-8733.0
KLKB1	-8735.0
PCCA	-8821.0
TNKS	-8839.0
MNAT1	-8852.0
ICOS	-8862.0
FGF9	-8873.0
PML	-8888.0
GALT	-8914.0
RPS20	-8922.0
ALG1	-8949.0
CCR5	-8977.0
RPL39L	-8982.0
SRC	-9011.0
HHAT	-9053.0
CYSLTR2	-9085.0
DERL1	-9113.0
MMAB	-9123.0
MCCC1	-9147.0
FOXO1	-9173.0
CAMK4	-9185.0
UVRAG	-9200.0
TBP	-9220.0
ESR1	-9230.0
ESR2	-9236.0
S1PR1	-9239.0
PSMC4	-9306.0
PTGIR	-9321.0
EIF2AK2	-9395.0
EED	-9417.0
RPL23A	-9477.0
SLC35A3	-9525.0
CCNT1	-9570.0
SEMA5A	-9572.0
CD320	-9575.0
RICTOR	-9593.0
NUP43	-9595.0
NPM1	-9596.0
IMPDH2	-9608.0
CPSF4	-9615.0
NCBP2	-9624.0
MAPK8	-9646.0
RPS27	-9651.0
PIK3R1	-9725.0
TXNIP	-9792.0
PSIP1	-9800.0
DDX5	-9806.0
GALNT12	-9814.0
ALG9	-9826.0
RANBP1	-9854.0
CD28	-9858.0
HEY2	-9918.0
EZH2	-9929.0
MTOR	-9948.0
ITPR3	-9955.0
PORCN	-9992.0
GPR150	-10012.0
CYP2R1	-10045.0
PSME1	-10138.0
MPI	-10185.0
ZC3HAV1	-10197.0
NUP35	-10206.0
SPON1	-10222.0
NUP155	-10291.0
AXIN1	-10310.0
KAT2A	-10374.0
NUP160	-10383.0
CYFIP2	-10387.0
PSME2	-10415.0
LIG1	-10471.0
PLCG1	-10473.0
PRKX	-10527.0
NUP107	-10570.0
DAXX	-10582.0
MPRIP	-10647.0
SIN3A	-10648.0
IPO5	-10677.0
EPM2A	-10694.0
GPR25	-10714.0
NUP210	-10725.0
SV2A	-10729.0
FEN1	-10740.0
DVL2	-10753.0
ADAMTS10	-10823.0
MC1R	-10836.0
MUTYH	-10856.0
MUC12	-10883.0
ABI2	-10893.0
ADAMTS4	-10919.0
SFTPD	-10938.0
MECP2	-10955.0
P2RY11	-10982.0
ITGA4	-11003.0
KIT	-11031.0
MIB2	-11044.0
NUP88	-11046.0
JAK1	-11075.0
AMER1	-11097.0
ANAPC5	-11108.0
CDK4	-11138.0
TENT4A	-11171.0
RIPK1	-11184.0
JAG2	-11198.0
RNMT	-11210.0
SSRP1	-11213.0
SLC24A1	-11214.0
NUP205	-11250.0
PEBP1	-11270.0
SLC2A1	-11299.0
MSH2	-11345.0
CDC23	-11349.0
PSMB9	-11362.0
DBP	-11405.0
CD3G	-11409.0
PPP2R5C	-11413.0
NEURL1	-11443.0
SERPING1	-11444.0
PDGFRB	-11452.0
SUPT16H	-11458.0
CUL1	-11467.0
SLC12A3	-11477.0
NCK1	-11488.0
LCK	-11492.0
CDH1	-11512.0
ADAMTS1	-11537.0
TLR3	-11538.0
SMAD3	-11541.0
H2AW	-11543.0
NUP188	-11545.0
MMAA	-11577.0
PARP16	-11583.0
PARP1	-11586.0
CDKN1C	-11587.0
DUSP8	-11604.0
WDR48	-11633.0
CCND2	-11649.0
CCNE1	-11655.0
B3GLCT	-11660.0
FCGR3A	-11661.0
RANGAP1	-11665.0
VAMP2	-11692.0
GPR20	-11696.0
NUP93	-11700.0
SLC4A4	-11716.0
SLC25A4	-11722.0
CAMK2D	-11728.0
FZD4	-11733.0
ABCA3	-11748.0
FGFR2	-11753.0
FYN	-11758.0
PTGER4	-11767.0
HLCS	-11768.0
STAT1	-11769.0
GCLC	-11771.0
AGRN	-11794.0
AKT3	-11804.0
SLC20A2	-11832.0
DLL1	-11843.0
MCCC2	-11850.0
PRKACB	-11857.0
KPNA5	-11861.0
ANAPC1	-11870.0
CDC25B	-11871.0
MTR	-11878.0
ADRB2	-11879.0
POMGNT1	-11883.0
ST6GAL1	-11887.0
PARP14	-11897.0
RNF213	-11921.0
NMT2	-11923.0
SCT	-11927.0
PRR5	-11948.0
PTGDR	-11967.0
APOBEC3G	-11978.0
CYP2U1	-11986.0
PIK3R3	-12037.0
RNF43	-12040.0
AGK	-12045.0
GNGT2	-12070.0
RBBP7	-12085.0
GIPR	-12098.0
ISG15	-12099.0
BTD	-12100.0
NDC1	-12113.0
YES1	-12143.0
VIPR2	-12157.0
C3	-12243.0
CYP4F22	-12245.0
SPON2	-12248.0
ERBB2	-12281.0
CD247	-12295.0
TFDP2	-12315.0
FASLG	-12319.0

---

Metabolism of lipids

	643
set	Metabolism of lipids
setSize	625
pANOVA	1.26e-14
s.dist	0.181
p.adjustANOVA	9.04e-13

Top enriched genes

GeneID	Gene Rank
PPARG	9571
PLBD1	9569
CYP19A1	9565
CYP1B1	9556
CTSA	9555
PLB1	9542
HSD3B7	9497
GGT1	9495
CD36	9486
PLIN3	9485
HADHB	9462
TNFAIP8L3	9442
PRKACA	9441
ACOX2	9435
OLAH	9430
TSPO	9388
GPX1	9380
PCTP	9354
ACSL1	9334
LTA4H	9300

Click HERE to show all gene set members

GeneID	Gene Rank
PPARG	9571
PLBD1	9569
CYP19A1	9565
CYP1B1	9556
CTSA	9555
PLB1	9542
HSD3B7	9497
GGT1	9495
CD36	9486
PLIN3	9485
HADHB	9462
TNFAIP8L3	9442
PRKACA	9441
ACOX2	9435
OLAH	9430
TSPO	9388
GPX1	9380
PCTP	9354
ACSL1	9334
LTA4H	9300
AGPAT2	9286
DGAT2	9279
PLD1	9245
PLA2G4A	9234
CERS2	9183
ACER3	9166
CRLS1	9126
CARM1	9122
INPPL1	9115
MTMR3	9105
PTGR1	9097
ALOX5	9088
NEU1	9084
ARF1	9083
FIG4	9074
VAPA	9073
PIK3CB	9065
GK	9053
GBA	9040
SGMS2	9038
SBF2	9037
PNPLA2	9033
PISD	9013
GM2A	9002
PPT1	8997
BMX	8978
SUMF1	8969
ME1	8961
ACOX1	8954
CRAT	8952
MTF1	8921
SGMS1	8878
HSD17B4	8874
CHPT1	8870
PECR	8860
PLA2G15	8840
PGS1	8773
FAR2	8769
HEXB	8749
FAR1	8738
HADHA	8736
ACSL4	8735
LPCAT3	8695
ACSS3	8682
TBXAS1	8676
ELOVL3	8667
GLB1	8652
GDE1	8648
MBOAT7	8643
SMARCD3	8637
LPCAT2	8600
SPTLC1	8570
LPGAT1	8562
PTEN	8516
SLC44A1	8514
PTGS1	8495
ALDH3B1	8489
MBOAT2	8487
GALC	8476
GLTP	8455
GPCPD1	8420
SPTLC2	8413
ACADVL	8405
GLA	8404
ACAA1	8398
SLC27A1	8395
ASAH1	8368
SP1	8315
TXNRD1	8303
AGPAT1	8269
GPAT3	8266
VDR	8258
PLIN2	8254
LBR	8224
HMGCR	8207
SEC24D	8130
ACOT8	8129
HSD17B11	8101
MTMR10	8079
ARNT	8074
ALOX5AP	8054
RAB4A	8050
PCYT1B	8017
PLPP3	8015
MTMR14	7999
TBL1X	7984
NCOR2	7948
ACSL3	7928
SRD5A1	7921
ABHD5	7892
ALAS1	7891
CERT1	7872
MTMR6	7838
FADS1	7822
GLIPR1	7804
ARF3	7798
ELOVL7	7755
MGLL	7741
HPGD	7730
NFYC	7726
SPHK1	7724
PNPLA8	7718
SEC24A	7716
CDK19	7697
ALOX12	7677
SAMD8	7670
MED8	7625
ALOX15B	7608
RGL1	7604
DHRS7B	7583
GPD2	7553
RXRA	7513
NR1H2	7512
FDFT1	7450
PLD3	7441
STARD3NL	7438
SEC23A	7416
ARSB	7373
PIK3R6	7359
ABCD1	7330
HSD17B12	7286
ARSD	7273
PLD2	7268
AHR	7227
ELOVL1	7175
RAB5A	7166
PPP1CB	7093
RAB14	7090
OSBPL8	7064
ABHD3	7047
SLC22A5	7020
CYP51A1	6941
PCYT1A	6918
PSAP	6909
DHCR7	6900
PNPLA6	6897
MED20	6851
PTDSS1	6840
HACD4	6831
GNPAT	6803
SREBF2	6802
IDI1	6791
CDS2	6658
SREBF1	6642
SAR1B	6562
INSIG2	6542
NUDT19	6540
CPT2	6535
PIP5K1B	6526
ABHD4	6523
RUFY1	6499
OSBPL9	6497
OCRL	6436
CSNK2A2	6430
DBI	6372
PPP1CC	6334
CYP4F3	6333
SYNJ1	6310
CDIPT	6305
MED25	6290
DEGS1	6287
MTM1	6213
EP300	6208
CSNK2A1	6207
PIP5K1A	6198
EHHADH	6173
FABP5	6123
MED13L	6114
CHKA	6099
PIK3CD	6096
ELOVL5	6074
ORMDL2	6068
ABCA1	6066
ACOX3	6059
GDPD3	5993
NCOR1	5979
ESRRA	5973
CPNE3	5955
PTDSS2	5876
PITPNM1	5849
NDUFAB1	5846
NCOA6	5838
ABCC3	5806
CERS6	5802
APOA2	5784
PLA2G12A	5774
PLAAT1	5768
TNFAIP8L2	5726
B3GALNT1	5686
ACAT1	5575
PTGES	5538
MCAT	5524
ACOT13	5491
MBOAT1	5488
FDPS	5431
AGPS	5430
ACACA	5394
CYP2C9	5390
HMGCL	5372
DGAT1	5367
G0S2	5324
MED16	5319
DECR1	5280
ACOT9	5268
PIAS4	5248
ACLY	5214
GPX4	5204
OSBPL2	5188
CPT1A	5153
SUMO2	5062
PIK3R2	5051
SLC25A1	5044
ACAD10	4889
STARD10	4820
ACOXL	4818
FDXR	4803
HDAC3	4734
PIK3CA	4697
HSD17B13	4686
NSDHL	4673
TBL1XR1	4627
AGPAT3	4625
SPTSSA	4614
FHL2	4582
HACD1	4576
NCOA1	4563
MED18	4492
SCP2	4477
MED26	4456
OSBPL6	4454
PTGS2	4402
ACADS	4365
SQLE	4315
HSD17B2	4277
STS	4231
GPAT4	4202
PTGES3	4180
MAPKAPK2	4176
PLA2R1	4167
PPP1CA	4156
SCD	4108
SRD5A3	4089
SLC25A20	4046
CSNK2B	3987
FABP2	3977
PPARGC1A	3934
CYP27A1	3913
ACSM6	3895
MMUT	3861
HSD11B2	3843
MID1IP1	3751
MED22	3738
CPTP	3715
SEC24B	3655
HSD17B1	3651
LIPH	3648
NCOA3	3563
ACAA2	3544
NFYA	3506
ARSA	3499
CREBBP	3460
STARD7	3453
PIP5K1C	3436
SGPL1	3401
PMVK	3382
ACBD7	3347
ALB	3339
AKR1B15	3330
STARD3	3311
MED19	3287
MED4	3271
PIKFYVE	3232
TMEM86B	3157
PEMT	3135
GLB1L	3043
GBA2	3025
MED17	3008
MTMR4	2986
POMC	2971
PHOSPHO1	2963
MBTPS1	2958
SPHK2	2863
DHCR24	2834
TAZ	2765
SLC44A2	2733
MSMO1	2601
MED13	2566
KPNB1	2491
PLPP2	2398
SMPD2	2340
UGCG	2292
PTPMT1	2290
VAPB	2225
ACER2	2079
CBR1	2072
PIK3CG	2046
MED12	2042
SPTLC3	2027
PRKAG2	1942
FDX1	1928
CCNC	1883
CAV1	1856
PIK3C2G	1751
FADS2	1658
PIK3C3	1626
MTMR9	1492
MED31	1486
TECRL	1389
PTGR2	1319
HEXA	1274
GSTM4	1226
LRP2	1222
HTD2	1195
CEPT1	1134
PLA2G2D	1125
PRKD3	1115
NCOA2	1109
SMPD1	1095
PLA2G4D	1074
NUDT7	1055
DECR2	957
CSNK1G2	899
ALDH3A2	887
NPAS2	873
PPARA	865
PLEKHA4	836
ABCC1	589
ECI1	512
THRAP3	398
AACS	344
AKR1C1	280
MED7	178
MBTPS2	77
CYP1A2	7
ENPP6	-15
FAM120B	-24
VAC14	-91
LCLAT1	-198
MED14	-205
CYP46A1	-326
LTC4S	-354
ACSF3	-368
GRHL1	-470
ACADL	-490
TNFAIP8	-517
GGT5	-679
FASN	-702
MED11	-713
ACOT11	-716
UBE2I	-746
SLC27A3	-819
MED6	-888
GPS2	-914
PLAAT2	-983
GGPS1	-996
CYP4F8	-1028
CBR4	-1253
ACBD5	-1261
ACSBG1	-1271
ACADM	-1308
STAR	-1393
MED28	-1397
MOGAT3	-1409
PLEKHA2	-1411
ETNK1	-1416
HILPDA	-1540
MTMR12	-1597
HACD2	-1729
PLEKHA6	-1731
SLC10A1	-1779
CDK8	-1997
HMGCS1	-2006
INPP5K	-2022
OXCT2	-2179
CERS5	-2238
MTMR2	-2283
MFSD2A	-2291
ECHS1	-2312
PIP4K2A	-2339
PIK3R5	-2346
SEC24C	-2615
PI4KA	-2619
OSBP	-2661
ARV1	-2728
DPEP2	-2760
PLA2G4C	-2813
DPEP3	-2980
STARD5	-3034
PLEKHA8	-3069
PPM1L	-3124
ACOT7	-3163
PHYH	-3203
RXRB	-3221
CHKB	-3255
CYP24A1	-3354
PNPLA4	-3380
CYP27B1	-3407
PITPNM3	-3415
NR1H3	-3418
CPNE1	-3422
CDS1	-3424
MTMR1	-3436
CERS3	-3472
ANGPTL4	-3500
PLIN1	-3507
SLC44A5	-3526
GPX2	-3560
OSBPL10	-3564
MTMR7	-3581
SC5D	-3584
FA2H	-3657
ACAT2	-3679
SLC27A5	-3685
PLD6	-3782
NEU3	-3800
ACP6	-3830
PLA2G10	-3844
SLC27A2	-3903
INPP5D	-3984
PIK3R4	-4040
STARD4	-4062
MED1	-4082
SCAP	-4090
SIN3B	-4201
KDSR	-4208
CYP7B1	-4321
ACBD4	-4363
PI4KB	-4503
CHD9	-4532
CPT1B	-4560
GDPD1	-4597
FAAH2	-4612
ACOT1	-4667
LGMN	-4724
MCEE	-4753
ARSG	-4809
FDX2	-4838
PITPNM2	-4859
INPP5F	-4892
PLEKHA5	-5028
GPAT2	-5033
ABCB4	-5056
PPARGC1B	-5117
PLEKHA3	-5120
CERS4	-5145
UGT8	-5170
PIK3C2A	-5233
FAAH	-5249
PLPP1	-5262
CERK	-5289
PRXL2B	-5372
TGS1	-5487
LPIN3	-5491
MED30	-5533
HSD17B3	-5596
ARSJ	-5603
MED21	-5663
ACSL6	-5710
MIGA2	-5745
ELOVL4	-5763
OSBPL1A	-5827
FITM2	-5856
TRIB3	-5896
AHRR	-5913
MVD	-5926
ORMDL1	-5997
PPARD	-6092
AKR1C2	-6176
PON2	-6202
FITM1	-6216
CYP2J2	-6350
PNPLA7	-6399
ALOX12B	-6526
PLA2G4B	-6650
PI4K2A	-6675
PLAAT3	-6689
MED23	-6699
CUBN	-6752
PTGES2	-6796
RAN	-6874
ARNTL	-6899
GPD1	-6946
LPIN2	-6965
CPNE7	-7027
AMACR	-7084
PITPNB	-7128
TM7SF2	-7146
MECR	-7352
MIGA1	-7418
CLOCK	-7458
MED24	-7462
ACSM3	-7466
LPCAT1	-7557
INPP5E	-7633
PIP4K2B	-7720
THEM5	-7835
ACER1	-7840
SCD5	-7947
MED29	-8038
PCCB	-8040
PRKAB2	-8083
CYP2D6	-8194
LPCAT4	-8224
NRF1	-8292
INPP4B	-8398
MVK	-8435
SYNJ2	-8530
AGPAT4	-8554
NR1D1	-8603
MED10	-8659
PCCA	-8821
PRKD2	-8832
MED9	-8957
LIPE	-8958
SPTSSB	-8961
PEX11A	-9013
MORC2	-9057
ASAH2	-9155
HSD17B7	-9238
CYP2E1	-9284
ETNK2	-9291
HELZ2	-9313
MED27	-9333
SACM1L	-9356
TECR	-9443
SGPP2	-9574
PIK3R1	-9725
AGPAT5	-9755
INPP4A	-9767
MLYCD	-9783
ACACB	-9846
EPHX2	-9860
MTMR8	-9937
NFYB	-9957
MED15	-9976
GPAM	-9993
ORMDL3	-9994
CYP2R1	-10045
TNFAIP8L1	-10058
PTPN13	-10143
ACOT2	-10226
ACAD11	-10314
PLPP6	-10392
PIK3C2B	-10393
FABP3	-10400
BDH1	-10426
ALOX15	-10452
HSD17B8	-10518
LSS	-10526
SBF1	-10529
INSIG1	-10566
GDPD5	-10605
GPD1L	-10644
SIN3A	-10648
ACSL5	-10681
SLC25A17	-10715
HACD3	-10793
ACOT4	-10881
SELENOI	-10887
PTGDS	-10915
THEM4	-10987
ACBD6	-11027
PPT2	-11127
TIAM2	-11149
DEGS2	-11200
ARSK	-11217
BDH2	-11263
PCYT2	-11296
HADH	-11322
LPIN1	-11358
PIP4K2C	-11384
ACSF2	-11403
OXCT1	-11518
DDHD1	-11559
MMAA	-11577
ELOVL6	-11588
DDHD2	-11651
OSBPL7	-11654
ESYT2	-11669
TSPOAP1	-11680
SMPD4	-11741
AKR1B1	-11747
HACL1	-11772
ECI2	-11802
PRKACB	-11857
RORA	-11872
OSBPL3	-11889
CROT	-11919
CYP2U1	-11986
PLA2G6	-12020
PI4K2B	-12022
PLEKHA1	-12032
PIK3R3	-12037
AGK	-12045
EBP	-12055
SUMF2	-12066
ESYT1	-12107
AKR1C3	-12115
PLAAT4	-12168
OSBPL5	-12179
SMPD3	-12182
SGPP1	-12194
TNFRSF21	-12219
CYP4F22	-12245
PLD4	-12302

---

Transport of small molecules

	1288
set	Transport of small molecules
setSize	561
pANOVA	2.09e-14
s.dist	0.189
p.adjustANOVA	1.42e-12

Top enriched genes

GeneID	Gene Rank
MICU1	9516
CYB5R1	9511
ATP6V0A1	9483
SLC1A3	9482
ASPH	9469
FBXL5	9458
PRKACA	9441
GNG10	9436
CA1	9414
AQP9	9376
SLC36A1	9314
ATP6V1A	9301
ATP6V0D1	9298
MCU	9283
ANO10	9276
TRPV4	9236
SLC22A4	9232
PCSK9	9229
BSG	9214
SLC4A1	9198

Click HERE to show all gene set members

GeneID	Gene Rank
MICU1	9516
CYB5R1	9511
ATP6V0A1	9483
SLC1A3	9482
ASPH	9469
FBXL5	9458
PRKACA	9441
GNG10	9436
CA1	9414
AQP9	9376
SLC36A1	9314
ATP6V1A	9301
ATP6V0D1	9298
MCU	9283
ANO10	9276
TRPV4	9236
SLC22A4	9232
PCSK9	9229
BSG	9214
SLC4A1	9198
FURIN	9162
SLC11A1	9152
TRPM2	9149
SLC2A3	9144
ATP6V1D	9118
ATP6V0C	9113
ADCY3	9101
HBA1	9095
CLTC	9056
DMTN	9014
ATP6V1B2	9005
PARL	8988
SLC6A6	8958
ERLIN2	8899
HFE	8894
SLC16A3	8884
GNG5	8866
OS9	8845
PCSK6	8824
ERLIN1	8806
SLC39A1	8776
NCEH1	8737
RAB11A	8715
SLC31A1	8706
ATP6V0B	8701
FTL	8698
SLC22A15	8697
AP2M1	8673
ATP6V0E1	8662
ATP6V1C1	8628
CYB5R2	8623
PRKAR1A	8616
ALAD	8605
SLCO2B1	8590
PSMB7	8535
HBB	8528
SLC39A8	8522
SLC44A1	8514
SLC15A3	8507
PSMD4	8498
P4HB	8452
CA4	8447
CYB5R4	8433
ATP11A	8431
CLTA	8402
SLC8A1	8400
SLC27A1	8395
PSME3	8331
SLCO3A1	8330
GNB1	8278
GNB2	8234
SLC12A6	8216
SOAT1	8202
HMOX1	8196
PSMB5	8188
ATP6V1H	8119
SLC43A2	8112
ATP6V1E1	8107
AP2S1	8080
ATP2A2	8071
SLC26A6	8066
PRKAR1B	8040
ATP6AP1	8035
GNAS	8019
SLC9A1	8016
ANO6	8005
SLC30A1	8003
RAF1	7991
NEDD4L	7972
VDAC2	7947
PSMD6	7881
SLC8B1	7824
SLC40A1	7793
BEST1	7761
LCN2	7752
SLC35D2	7734
MCOLN1	7715
SLC24A4	7713
PSMD9	7712
HDLBP	7690
RUNX1	7591
AQP10	7571
ABCC4	7559
SLC6A9	7554
NR1H2	7512
PSMD2	7470
SLC4A2	7461
APOBR	7456
PLTP	7453
SGK3	7408
AP2A2	7360
AQP1	7352
CLCN3	7347
PSMA1	7346
SLC36A4	7336
ABCD1	7330
SLC9A9	7329
SLC35A1	7309
FKBP1B	7302
PSMD1	7283
TCIRG1	7266
PSMB3	7265
EMB	7208
PSMA7	7174
FXYD6	7144
GNB4	7138
PSMC1	7096
ATP8B4	7041
MMGT1	7040
SLC7A7	7038
OSTM1	7022
BEST3	7021
SLC22A5	7020
STOM	6963
VCP	6955
PSMB6	6927
ATP7B	6888
CTNS	6869
TTYH3	6865
SLC2A9	6839
SEL1L	6834
PRKAR2B	6824
EIF2S3	6808
TRPM4	6741
UBB	6737
PSMF1	6724
CLCN5	6717
PSMC6	6701
TPCN2	6668
SRI	6664
AP2A1	6628
GNG11	6612
NEDD8	6597
RNF185	6584
SAR1B	6562
RYR2	6553
LIPA	6547
PSMD12	6537
SLC28A3	6477
ATP1B2	6466
ABCB6	6425
SLC2A14	6412
SLC38A2	6385
SLC1A5	6354
SLC25A6	6340
LDLR	6329
PSMD11	6296
PRKAR2A	6265
EIF2S2	6203
ATP11B	6172
ANO8	6166
YME1L1	6107
ATP2C2	6078
STEAP3	6076
ABCA1	6066
PSMD7	6017
PSMD13	5991
SCARB1	5987
PSMA6	5978
ATP6V1F	5949
ABCB10	5928
PSMD8	5845
PEX19	5836
ABCC3	5806
ADD1	5789
APOA2	5784
ATP6V1E2	5776
ATP9B	5695
BSND	5676
SLC35B3	5625
CYBRD1	5603
ABCC6	5598
UNC79	5479
NPC2	5468
SLC24A2	5463
PSMA2	5433
SLC24A3	5407
WNK1	5283
SLC22A16	5281
TPCN1	5267
SLC29A3	5252
IREB2	5231
ADCY4	5226
SLC3A2	5197
SLCO4A1	5181
SLC16A7	5137
SLC17A5	5092
SLC9A8	5056
SLC66A1	5029
ABCD3	5014
LRRC8D	5001
SLC5A9	4956
SLC39A7	4953
ATP2C1	4907
PCSK5	4881
CLCN4	4880
RAB11FIP2	4873
FTH1	4867
SLC9A6	4834
CLCN1	4809
SLC22A1	4772
ATP8B3	4757
PSMD3	4693
SGK1	4642
SLC39A3	4591
ANO5	4546
SLC39A4	4520
SLC16A1	4517
TRPM6	4465
SEM1	4436
UBC	4421
SKP1	4349
GNG8	4339
EIF2S1	4338
NIPA2	4308
VDAC1	4300
ATP9A	4239
SLC22A18	4137
PSMB2	4103
CUTC	4000
ATP6V1G1	3989
SLC15A4	3867
ADD3	3789
SLC50A1	3740
SLC35B4	3567
CA2	3565
SLC15A2	3528
TSC22D3	3515
PSMD5	3507
SLCO4C1	3445
PSMB1	3422
NIPAL1	3365
SLC6A12	3361
ALB	3339
SLC35A2	3310
ATP13A2	3261
SLC7A5	3224
ATP11C	3201
LRRC8B	3180
BEST2	3178
ABCG8	3112
DERL2	3093
ABCA7	3090
SLC2A13	3024
MBTPS1	2958
CETP	2908
SLC25A18	2883
SLC12A4	2880
LPL	2853
ATP1A1	2849
SLC12A1	2813
ATP10B	2760
SLC35C1	2739
CFTR	2738
SLC44A2	2733
PSMD14	2703
MAGT1	2698
PSMC2	2696
SLC25A29	2613
PSMB4	2552
ABCC5	2534
SLC27A4	2527
ATP10D	2465
CLCN6	2278
PSMC3	2018
SLC16A8	2015
SLC7A8	1948
CLCN7	1943
CAMK2G	1888
SLC8A3	1830
NIPAL2	1823
SLC46A1	1752
SLC29A1	1728
PSMD10	1646
WNK2	1614
TFRC	1578
RSC1A1	1359
SLC34A2	1301
TRPC4AP	1283
TF	1172
UBA52	1071
TRPM3	1012
APOD	1010
GNG3	894
SLC25A5	892
SLC17A7	864
SLC5A12	778
ERLEC1	775
ATP1A4	759
LIPC	750
SLC7A9	708
ATP7A	647
LRRC8C	637
ABCC1	589
VDAC3	483
GNB5	467
AHCYL2	400
AVPR2	306
SLC18A2	293
SMDT1	277
BMP1	255
SLC11A2	243
ADCY9	146
LCN15	113
APOE	103
MBTPS2	77
ABCG2	62
SLC30A6	34
SCNN1A	-149
PHB2	-230
SLC28A2	-261
SLC30A2	-477
PSMA4	-538
UNC80	-547
NIPAL4	-622
ARL2	-643
MICU2	-727
TTYH1	-799
SLC1A2	-802
PMPCB	-822
CLCN2	-838
LCAT	-877
ATP1B3	-884
SLC6A1	-924
PSMC5	-948
ATP2A3	-999
ABCB8	-1049
SLC1A6	-1095
SLC5A11	-1113
LIPG	-1188
SLC36A2	-1224
SLC13A5	-1420
GLRX3	-1460
CP	-1599
SLC34A1	-1698
ADCY6	-1746
ABCA9	-1831
ABCB7	-1851
TRPC6	-1948
ABCC2	-1990
CALM1	-2048
SLC33A1	-2159
GNG4	-2175
ABCB9	-2182
TRPM8	-2190
ATP6V1C2	-2222
ASIC1	-2252
SLC12A7	-2273
SLC22A17	-2413
SLC29A4	-2435
ANO7	-2457
SLC30A5	-2484
AQP11	-2498
AP2B1	-2748
SLC2A6	-2761
GNB3	-2776
ADCY2	-2874
SLC26A2	-2930
TRPM5	-2995
SOAT2	-3001
SLC13A4	-3018
PHB	-3050
MFSD4B	-3065
PSMB8	-3080
SLC47A1	-3172
ZDHHC8	-3275
ADCY7	-3307
NR1H3	-3418
MCUB	-3471
ANGPTL4	-3500
SLC44A5	-3526
AMN	-3675
SLC14A2	-3992
MYLIP	-4005
KCNJ11	-4054
STOML2	-4085
SLC16A10	-4178
ATP8A2	-4278
VLDLR	-4336
ATP2A1	-4436
MCOLN3	-4450
SLC30A7	-4483
TTYH2	-4501
SLC4A5	-4543
LETM1	-4619
SLC5A2	-4689
SLC43A1	-4705
ABCC9	-4801
WNK3	-4864
ABCC10	-4953
GNG7	-5049
ABCB4	-5056
ATP2B4	-5075
ADD2	-5083
TRPV6	-5084
ATP8B1	-5086
SCNN1D	-5093
SLC6A20	-5246
PSMA3	-5314
SLC5A5	-5315
SLC5A6	-5458
FXYD1	-5471
TRPV2	-5519
RYR1	-5522
ATP13A1	-5528
SLC2A10	-5543
FXYD2	-5576
SLC7A11	-5652
PSMB10	-5768
SLC38A5	-5793
PMPCA	-5989
SLC2A12	-6031
SLC9B1	-6076
PSME4	-6099
PSMA5	-6154
SLC7A6	-6200
PDZD11	-6343
SGK2	-6352
SLC25A22	-6357
SLC7A1	-6448
AQP7	-6479
RNF5	-6497
SLC39A5	-6548
CAND1	-6550
SLC39A14	-6570
MRS2	-6728
CUBN	-6752
SLC26A11	-6793
SLC35D1	-6818
ARL2BP	-6846
SLC14A1	-6859
SLC2A11	-6868
ASIC3	-6882
RPS27A	-6894
SLC47A2	-6929
CLIC2	-6948
DERL3	-7065
SLC9A7	-7104
LSR	-7139
SLC45A3	-7157
SLC4A10	-7162
SLC34A3	-7270
MICU3	-7281
FXYD7	-7299
TRPM7	-7486
PSMA8	-7559
GNG2	-7809
ATP13A4	-7845
SLC39A6	-7850
LMF2	-7868
SLC9A5	-7948
SLC9A3	-8009
ABCG1	-8065
SLC26A1	-8131
LRRC8A	-8257
FLVCR1	-8309
ADCY5	-8315
SLC3A1	-8414
ATP2B1	-8415
ACO1	-8506
ABCA5	-8542
SLC29A2	-8681
ANO9	-8697
BEST4	-8885
LDLRAP1	-8898
MYO5B	-9039
ATP1B1	-9055
CES3	-9086
ABCA10	-9094
DERL1	-9113
LMF1	-9114
FXYD3	-9151
SLC5A10	-9204
TRPV1	-9261
ATP6V1G2	-9275
PSMC4	-9306
AQP3	-9385
TRPC1	-9415
SLC35A3	-9525
TRPC3	-9546
SLC1A7	-9728
ABCF1	-9742
SLC39A10	-9762
A2M	-9822
TFR2	-9972
WWP1	-10036
RYR3	-10081
PSME1	-10138
SLC35B2	-10159
ABCA6	-10189
NIPAL3	-10275
SLC4A8	-10280
SLC25A10	-10337
PSME2	-10415
ABCA2	-10483
ATP8B2	-10510
CYB5RL	-10650
SPG7	-10666
ABCD2	-10799
AFG3L2	-10970
LCN12	-11010
TRPV3	-11140
SLC41A1	-11157
SLC5A3	-11182
AKAP1	-11195
SLC24A1	-11214
SLC13A3	-11234
SLC38A1	-11235
SLC9B2	-11248
SLC2A1	-11299
NIPA1	-11311
SLC1A4	-11317
SLC12A2	-11328
PSMB9	-11362
CUL1	-11467
ATP6V0E2	-11475
SLC12A3	-11477
SLC20A1	-11534
ATP1A3	-11645
MCOLN2	-11659
SLC18A1	-11686
SLC4A4	-11716
SLC25A4	-11722
CAMK2D	-11728
ABCA3	-11748
ANKH	-11749
ATP8A1	-11780
HMOX2	-11783
SLC2A8	-11810
SLC20A2	-11832
SLC4A7	-11839
PRKACB	-11857
PEX3	-11998
GNGT2	-12070
ATP10A	-12128
SLC25A26	-12173
ABCB1	-12187
ATP6V0A2	-12193
NPC1	-12200
SLC4A3	-12267
SLC41A2	-12331

---

Toll Like Receptor 4 (TLR4) Cascade

	1239
set	Toll Like Receptor 4 (TLR4) Cascade
setSize	121
pANOVA	4.08e-14
s.dist	0.398
p.adjustANOVA	2.65e-12

Top enriched genes

GeneID	Gene Rank
S100A12	9567
CD36	9486
ITGAM	9453
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
UBE2D1	9125
APP	9123
MAPK3	9078
TLR2	9069
TLR1	9041
MAP2K6	9010
TLR4	8981
MAP2K1	8960
IRAK3	8947
TLR6	8931
ITGB2	8908
LY96	8871
MAP2K3	8785

Click HERE to show all gene set members

GeneID	Gene Rank
S100A12	9567
CD36	9486
ITGAM	9453
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
UBE2D1	9125
APP	9123
MAPK3	9078
TLR2	9069
TLR1	9041
MAP2K6	9010
TLR4	8981
MAP2K1	8960
IRAK3	8947
TLR6	8931
ITGB2	8908
LY96	8871
MAP2K3	8785
UBE2D3	8710
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959
RPS6KA1	7800
LY86	7774
PPP2CB	7769
PELI3	7736
MAPK1	7520
TANK	7494
DNM3	7167
BTK	7156
TAB2	7070
MAP2K4	6948
NFKBIA	6835
UBB	6737
PELI1	6596
BPI	6538
TICAM1	6380
NFKB1	6367
FBXW11	6282
MAP3K8	6262
TICAM2	6244
FOS	6179
DNM2	6163
IRAK1	6159
ATF1	5790
FADD	5746
TAB1	5711
TIRAP	5700
UBE2V1	5681
TNIP2	5630
IKBKG	5434
PTPN11	5383
MAP3K1	5160
PLCG2	5103
ECSIT	4997
IKBKE	4779
BIRC2	4749
UBE2D2	4721
PPP2R1A	4669
UBC	4421
DUSP6	4367
SKP1	4349
RIPK3	4262
MAPKAPK2	4176
MAPK10	4136
JUN	3964
MAPK11	3955
SOCS1	3886
DNM1	3526
RPS6KA2	3177
TAB3	3165
TBK1	3159
RPS6KA3	3012
MAP3K7	2453
PPP2R5D	2440
ATF2	2110
UBE2N	1951
MAP2K7	1647
AGER	1309
VRK3	1293
UBA52	1071
RIPK2	1042
ELK1	1040
NKIRAS1	387
NFKBIB	-88
HMGB1	-200
TRAF6	-241
PPP2R1B	-246
MEF2C	-319
CD180	-761
NFKB2	-865
MAPK7	-1294
CREB1	-1382
RELA	-1807
DUSP7	-3253
BTRC	-4932
S100B	-5025
IKBKB	-5290
TRAF3	-5296
DUSP4	-6432
RPS27A	-6894
MAPK9	-7182
IRF3	-8479
IRF7	-8889
MAPK8	-9646
IRAK2	-9718
SIGIRR	-10688
BIRC3	-10830
RIPK1	-11184
CASP8	-11463
CUL1	-11467
RPS6KA5	-11616
SARM1	-11973
PTPN4	-12133
NOD1	-12234

---

rRNA processing

	1354
set	rRNA processing
setSize	219
pANOVA	1.68e-13
s.dist	-0.289
p.adjustANOVA	1.04e-11

Top enriched genes

GeneID	Gene Rank
LAS1L	-12198
NAT10	-11864
ELAC2	-11818
RBM28	-11682
BMS1	-11612
PDCD11	-11549
NOP56	-11502
DKC1	-11479
EXOSC10	-11414
UTP4	-11391
TFB1M	-11382
EXOSC8	-11326
DDX47	-11150
WDR46	-11050
NOP14	-10925
EXOSC2	-10865
NOL6	-10847
PELP1	-10841
EXOSC7	-10756
IMP4	-10678

Click HERE to show all gene set members

GeneID	Gene Rank
LAS1L	-12198
NAT10	-11864
ELAC2	-11818
RBM28	-11682
BMS1	-11612
PDCD11	-11549
NOP56	-11502
DKC1	-11479
EXOSC10	-11414
UTP4	-11391
TFB1M	-11382
EXOSC8	-11326
DDX47	-11150
WDR46	-11050
NOP14	-10925
EXOSC2	-10865
NOL6	-10847
PELP1	-10841
EXOSC7	-10756
IMP4	-10678
UTP15	-10548
MTERF4	-10534
UTP20	-10433
EXOSC9	-10425
NOB1	-10365
HEATR1	-10256
CSNK1E	-10239
NOL11	-10225
NOL9	-10200
EMG1	-10162
FBL	-10108
RRP9	-10053
NOP58	-10035
EXOSC6	-10009
THUMPD1	-9861
TEX10	-9856
WDR75	-9808
RPS27	-9651
TSR1	-9633
MRM1	-9547
NOP2	-9504
RPL23A	-9477
NCL	-9396
IMP3	-9295
RPL39L	-8982
RPS20	-8922
KRR1	-8597
RPL3	-8478
GNL3	-8367
RPP25	-8346
DHX37	-8302
RPL35	-8239
RPP30	-8204
RPL13A	-8123
DIMT1	-8084
MPHOSPH10	-7881
RPS29	-7794
MRM3	-7652
RPS18	-7641
WDR43	-7562
RPL36A	-7442
RPS11	-7122
MT-TL2	-7049
RPL12	-7038
RPS19	-7037
GAR1	-7020
RPL30	-6995
PNO1	-6955
SNU13	-6919
RPLP2	-6915
RPS27A	-6894
RPL41	-6877
RPP38	-6855
RPL34	-6807
MT-ND2	-6660
RPL10A	-6644
RPL26	-6636
WDR3	-6598
RPL32	-6577
RPL10	-6562
RPL14	-6518
RPL21	-6481
RPL37	-6401
RPL27A	-6321
RPS23	-6279
RPL11	-6275
RPS25	-6246
RPL19	-6242
RPS17	-6223
RPSA	-6219
RPS6	-6100
RPL35A	-6080
RPL18A	-6029
RPS12	-5985
RPS4X	-5969
NIP7	-5955
RPL38	-5890
RPL24	-5882
RPS3	-5833
RPS15A	-5695
RPS10	-5686
DCAF13	-5627
NOC4L	-5514
RPS14	-5485
RPS5	-5478
RPL17	-5464
RPL36	-5287
BOP1	-5238
RPP21	-5229
RPL18	-5054
RPS7	-5016
NSUN4	-4817
RPL22	-4738
RPP40	-4722
RPS3A	-4702
RPS28	-4647
RPL5	-4631
RPS16	-4570
UTP6	-4523
RPS2	-4509
RPL31	-4507
TRMT10C	-4493
EXOSC5	-4414
BYSL	-4399
DIS3	-4360
LTV1	-4249
EBNA1BP2	-4176
RPS21	-4115
RPL37A	-4004
FTSJ3	-3954
WDR36	-3840
RIOK1	-3784
MT-TV	-3737
RPL7A	-3699
RPS15	-3698
MT-ND1	-3693
MT-ND3	-3687
RPL29	-3604
RPL4	-3592
NHP2	-3499
TBL3	-3473
RPL13	-3461
RPL6	-3382
RPL23	-3352
RRP1	-3119
RPL39	-3047
MT-ATP8	-2961
UTP3	-2941
RPL27	-2934
MT-TL1	-2879
RRP7A	-2826
MT-TF	-2732
MTREX	-2653
WDR18	-2407
MT-CYB	-2314
SNORD3A	-2302
MT-ND5	-2218
RPS8	-2138
MT-ATP6	-2106
MT-ND4L	-2067
PES1	-2028
RPL7	-2018
RPL9	-1827
UTP14A	-1797
RPS13	-1759
RPL22L1	-1643
UTP14C	-1641
RRP36	-1507
MT-TM	-1490
RPL28	-1469
RPS26	-1443
RPL8	-1242
RPLP0	-1054
RPL15	-1017
PWP2	-991
EXOSC1	-976
RCL1	-834
FAU	-402
MT-RNR1	-288
RPS24	-282
RPS4Y1	-222
RPLP1	-65
MT-CO2	35
MT-CO3	47
RPL36AL	91
EXOSC3	489
DDX52	502
TRMT112	586
MT-CO1	675
MT-ND4	830
RIOK2	947
UBA52	1071
MRM2	1500
RPS27L	2117
MT-RNR2	2190
MPHOSPH6	2244
CSNK1D	2412
SENP3	3029
RPP14	3109
DDX21	3131
PRORP	3415
C1D	3623
ISG20L2	3845
TSR3	3909
HSD17B10	4284
RPL3L	4539
FCF1	4556
UTP11	4710
DDX49	4940
NOL12	4966
UTP18	5163
WDR12	5287
RPS9	5496
ERI1	5597
RPL26L1	7295
EXOSC4	7781
NOP10	8462
RIOK3	8755
XRN2	9415

---

rRNA processing in the nucleus and cytosol

	1356
set	rRNA processing in the nucleus and cytosol
setSize	190
pANOVA	2.49e-13
s.dist	-0.308
p.adjustANOVA	1.48e-11

Top enriched genes

GeneID	Gene Rank
LAS1L	-12198
NAT10	-11864
RBM28	-11682
BMS1	-11612
PDCD11	-11549
NOP56	-11502
DKC1	-11479
EXOSC10	-11414
UTP4	-11391
EXOSC8	-11326
DDX47	-11150
WDR46	-11050
NOP14	-10925
EXOSC2	-10865
NOL6	-10847
PELP1	-10841
EXOSC7	-10756
IMP4	-10678
UTP15	-10548
UTP20	-10433

Click HERE to show all gene set members

GeneID	Gene Rank
LAS1L	-12198
NAT10	-11864
RBM28	-11682
BMS1	-11612
PDCD11	-11549
NOP56	-11502
DKC1	-11479
EXOSC10	-11414
UTP4	-11391
EXOSC8	-11326
DDX47	-11150
WDR46	-11050
NOP14	-10925
EXOSC2	-10865
NOL6	-10847
PELP1	-10841
EXOSC7	-10756
IMP4	-10678
UTP15	-10548
UTP20	-10433
EXOSC9	-10425
NOB1	-10365
HEATR1	-10256
CSNK1E	-10239
NOL11	-10225
NOL9	-10200
EMG1	-10162
FBL	-10108
RRP9	-10053
NOP58	-10035
EXOSC6	-10009
THUMPD1	-9861
TEX10	-9856
WDR75	-9808
RPS27	-9651
TSR1	-9633
NOP2	-9504
RPL23A	-9477
NCL	-9396
IMP3	-9295
RPL39L	-8982
RPS20	-8922
KRR1	-8597
RPL3	-8478
GNL3	-8367
RPP25	-8346
DHX37	-8302
RPL35	-8239
RPP30	-8204
RPL13A	-8123
DIMT1	-8084
MPHOSPH10	-7881
RPS29	-7794
RPS18	-7641
WDR43	-7562
RPL36A	-7442
RPS11	-7122
RPL12	-7038
RPS19	-7037
GAR1	-7020
RPL30	-6995
PNO1	-6955
SNU13	-6919
RPLP2	-6915
RPS27A	-6894
RPL41	-6877
RPP38	-6855
RPL34	-6807
RPL10A	-6644
RPL26	-6636
WDR3	-6598
RPL32	-6577
RPL10	-6562
RPL14	-6518
RPL21	-6481
RPL37	-6401
RPL27A	-6321
RPS23	-6279
RPL11	-6275
RPS25	-6246
RPL19	-6242
RPS17	-6223
RPSA	-6219
RPS6	-6100
RPL35A	-6080
RPL18A	-6029
RPS12	-5985
RPS4X	-5969
NIP7	-5955
RPL38	-5890
RPL24	-5882
RPS3	-5833
RPS15A	-5695
RPS10	-5686
DCAF13	-5627
NOC4L	-5514
RPS14	-5485
RPS5	-5478
RPL17	-5464
RPL36	-5287
BOP1	-5238
RPP21	-5229
RPL18	-5054
RPS7	-5016
RPL22	-4738
RPP40	-4722
RPS3A	-4702
RPS28	-4647
RPL5	-4631
RPS16	-4570
UTP6	-4523
RPS2	-4509
RPL31	-4507
EXOSC5	-4414
BYSL	-4399
DIS3	-4360
LTV1	-4249
EBNA1BP2	-4176
RPS21	-4115
RPL37A	-4004
FTSJ3	-3954
WDR36	-3840
RIOK1	-3784
RPL7A	-3699
RPS15	-3698
RPL29	-3604
RPL4	-3592
NHP2	-3499
TBL3	-3473
RPL13	-3461
RPL6	-3382
RPL23	-3352
RRP1	-3119
RPL39	-3047
UTP3	-2941
RPL27	-2934
RRP7A	-2826
MTREX	-2653
WDR18	-2407
SNORD3A	-2302
RPS8	-2138
PES1	-2028
RPL7	-2018
RPL9	-1827
UTP14A	-1797
RPS13	-1759
RPL22L1	-1643
UTP14C	-1641
RRP36	-1507
RPL28	-1469
RPS26	-1443
RPL8	-1242
RPLP0	-1054
RPL15	-1017
PWP2	-991
EXOSC1	-976
RCL1	-834
FAU	-402
RPS24	-282
RPS4Y1	-222
RPLP1	-65
RPL36AL	91
EXOSC3	489
DDX52	502
TRMT112	586
RIOK2	947
UBA52	1071
RPS27L	2117
MPHOSPH6	2244
CSNK1D	2412
SENP3	3029
RPP14	3109
DDX21	3131
C1D	3623
ISG20L2	3845
TSR3	3909
RPL3L	4539
FCF1	4556
UTP11	4710
DDX49	4940
NOL12	4966
UTP18	5163
WDR12	5287
RPS9	5496
ERI1	5597
RPL26L1	7295
EXOSC4	7781
NOP10	8462
RIOK3	8755
XRN2	9415

---

Signaling by NOTCH

	1108
set	Signaling by NOTCH
setSize	183
pANOVA	3.32e-13
s.dist	0.312
p.adjustANOVA	1.79e-11

Top enriched genes

GeneID	Gene Rank
NUMB	9457
H2AJ	9418
TACC3	9389
H2BC21	9368
H2BC12	9178
FURIN	9162
NCSTN	9139
AGO4	9094
HDAC4	9057
MAML3	8965
H3-3A	8754
RBPJ	8744
ADAM10	8705
TLE3	8679
JAG1	8661
PSMB7	8535
ARRB2	8517
TFDP1	8500
PSMD4	8498
PSME3	8331

Click HERE to show all gene set members

GeneID	Gene Rank
NUMB	9457.0
H2AJ	9418.0
TACC3	9389.0
H2BC21	9368.0
H2BC12	9178.0
FURIN	9162.0
NCSTN	9139.0
AGO4	9094.0
HDAC4	9057.0
MAML3	8965.0
H3-3A	8754.0
RBPJ	8744.0
ADAM10	8705.0
TLE3	8679.0
JAG1	8661.0
PSMB7	8535.0
ARRB2	8517.0
TFDP1	8500.0
PSMD4	8498.0
PSME3	8331.0
EGF	8267.0
RAB6A	8223.0
PSMB5	8188.0
H2BC5	8163.0
H2BC11	8076.0
ATP2A2	8071.0
H2AC6	8070.0
WWP2	8046.0
NOTCH3	8004.0
TBL1X	7984.0
ADAM17	7980.0
NCOR2	7948.0
PSMD6	7881.0
PSEN1	7843.0
PSMD9	7712.0
PTCRA	7611.0
RUNX1	7591.0
H2BC4	7549.0
H2BC17	7502.0
PSMD2	7470.0
HIF1A	7404.0
PLXND1	7376.0
PSMA1	7346.0
RFNG	7317.0
PSMD1	7283.0
PSMB3	7265.0
PSMA7	7174.0
PSMC1	7096.0
PSMB6	6927.0
TLE4	6882.0
DTX2	6845.0
SEL1L	6834.0
H3C15	6780.5
E2F3	6744.0
UBB	6737.0
PSMF1	6724.0
PSMC6	6701.0
ST3GAL6	6671.0
PSMD12	6537.0
E2F1	6473.0
SIRT6	6321.0
PSMD11	6296.0
APH1B	6248.0
DTX4	6230.0
EP300	6208.0
H2AZ1	6126.0
TMED2	6098.0
HDAC7	6070.0
PSMD7	6017.0
PSMD13	5991.0
NCOR1	5979.0
PSMA6	5978.0
ST3GAL4	5930.0
PSMD8	5845.0
PSENEN	5833.0
YWHAZ	5687.0
AGO1	5660.0
HDAC2	5569.0
H2BC9	5461.0
H2BC15	5458.0
MAML1	5447.0
PSMA2	5433.0
NOTCH2	5276.0
SNW1	5255.0
PBX1	5182.0
H2AC20	5039.0
HDAC11	4790.0
HDAC5	4761.0
HDAC3	4734.0
NOTCH1	4733.0
PSMD3	4693.0
TBL1XR1	4627.0
SEM1	4436.0
UBC	4421.0
B4GALT1	4354.0
SKP1	4349.0
APH1A	4198.0
PSMB2	4103.0
RBX1	4039.0
JUN	3964.0
AKT1	3656.0
PSMD5	3507.0
CREBBP	3460.0
PSMB1	3422.0
DLGAP5	3185.0
YBX1	3172.0
HDAC8	3141.0
AGO2	3046.0
PSMD14	2703.0
PSMC2	2696.0
PSMB4	2552.0
MYC	2367.0
HDAC10	2302.0
POFUT1	2133.0
ARRB1	2098.0
PSMC3	2018.0
CCNC	1883.0
PSMD10	1646.0
ITCH	1394.0
HDAC9	1347.0
WWC1	1194.0
UBA52	1071.0
ELF3	676.0
ST3GAL3	485.0
HDAC1	394.0
PRKCI	-135.0
NBEA	-347.0
ACTA2	-430.0
MAML2	-476.0
PSMA4	-538.0
PSMC5	-948.0
ATP2A3	-999.0
AGO3	-1014.0
H2AZ2	-1266.0
CREB1	-1382.0
CDK8	-1997.0
KAT2B	-2393.0
NEURL1B	-2658.0
DTX1	-2958.0
MIB1	-2999.0
PSMB8	-3080.0
MDK	-3656.0
FCER2	-3678.0
ATP2A1	-4436.0
TNRC6B	-4558.0
MAMLD1	-4791.0
NOTCH4	-5200.0
PSMA3	-5314.0
TNRC6A	-5567.0
PSMB10	-5768.0
TLE2	-5817.0
MFNG	-5940.0
PSMA5	-6154.0
H2BU1	-6519.0
FBXW7	-6709.0
CCND1	-6847.0
RPS27A	-6894.0
TLE1	-7036.0
FLT4	-7288.0
HES1	-7731.0
IKZF1	-7757.0
PSEN2	-7844.0
HDAC6	-8348.0
LFNG	-8502.0
POGLUT1	-9193.0
PSMC4	-9306.0
HEY2	-9918.0
PSME1	-10138.0
KAT2A	-10374.0
PSME2	-10415.0
TP53	-10936.0
MIB2	-11044.0
JAG2	-11198.0
PSMB9	-11362.0
NEURL1	-11443.0
CUL1	-11467.0
SMAD3	-11541.0
TNRC6C	-11737.0
STAT1	-11769.0
DLL1	-11843.0
MOV10	-11980.0
GZMB	-12311.0
TFDP2	-12315.0

---

MyD88:MAL(TIRAP) cascade initiated on plasma membrane

	689
set	MyD88:MAL(TIRAP) cascade initiated on plasma membrane
setSize	92
pANOVA	3.67e-13
s.dist	0.438
p.adjustANOVA	1.79e-11

Top enriched genes

GeneID	Gene Rank
S100A12	9567
CD36	9486
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
APP	9123
MAPK3	9078
TLR2	9069
TLR1	9041
MAP2K6	9010
TLR4	8981
MAP2K1	8960
IRAK3	8947
TLR6	8931
LY96	8871
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255

Click HERE to show all gene set members

GeneID	Gene Rank
S100A12	9567
CD36	9486
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
APP	9123
MAPK3	9078
TLR2	9069
TLR1	9041
MAP2K6	9010
TLR4	8981
MAP2K1	8960
IRAK3	8947
TLR6	8931
LY96	8871
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959
RPS6KA1	7800
PPP2CB	7769
PELI3	7736
MAPK1	7520
BTK	7156
TAB2	7070
MAP2K4	6948
NFKBIA	6835
UBB	6737
PELI1	6596
NFKB1	6367
FBXW11	6282
MAP3K8	6262
FOS	6179
IRAK1	6159
ATF1	5790
TAB1	5711
TIRAP	5700
UBE2V1	5681
TNIP2	5630
IKBKG	5434
MAP3K1	5160
ECSIT	4997
PPP2R1A	4669
UBC	4421
DUSP6	4367
SKP1	4349
MAPKAPK2	4176
MAPK10	4136
JUN	3964
MAPK11	3955
SOCS1	3886
RPS6KA2	3177
TAB3	3165
RPS6KA3	3012
MAP3K7	2453
PPP2R5D	2440
ATF2	2110
UBE2N	1951
MAP2K7	1647
AGER	1309
VRK3	1293
UBA52	1071
RIPK2	1042
ELK1	1040
NKIRAS1	387
NFKBIB	-88
HMGB1	-200
TRAF6	-241
PPP2R1B	-246
MEF2C	-319
NFKB2	-865
MAPK7	-1294
CREB1	-1382
RELA	-1807
DUSP7	-3253
BTRC	-4932
S100B	-5025
IKBKB	-5290
DUSP4	-6432
RPS27A	-6894
MAPK9	-7182
MAPK8	-9646
IRAK2	-9718
SIGIRR	-10688
CUL1	-11467
RPS6KA5	-11616
NOD1	-12234

---

Toll Like Receptor 2 (TLR2) Cascade

	1237
set	Toll Like Receptor 2 (TLR2) Cascade
setSize	92
pANOVA	3.67e-13
s.dist	0.438
p.adjustANOVA	1.79e-11

Top enriched genes

GeneID	Gene Rank
S100A12	9567
CD36	9486
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
APP	9123
MAPK3	9078
TLR2	9069
TLR1	9041
MAP2K6	9010
TLR4	8981
MAP2K1	8960
IRAK3	8947
TLR6	8931
LY96	8871
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255

Click HERE to show all gene set members

GeneID	Gene Rank
S100A12	9567
CD36	9486
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
APP	9123
MAPK3	9078
TLR2	9069
TLR1	9041
MAP2K6	9010
TLR4	8981
MAP2K1	8960
IRAK3	8947
TLR6	8931
LY96	8871
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959
RPS6KA1	7800
PPP2CB	7769
PELI3	7736
MAPK1	7520
BTK	7156
TAB2	7070
MAP2K4	6948
NFKBIA	6835
UBB	6737
PELI1	6596
NFKB1	6367
FBXW11	6282
MAP3K8	6262
FOS	6179
IRAK1	6159
ATF1	5790
TAB1	5711
TIRAP	5700
UBE2V1	5681
TNIP2	5630
IKBKG	5434
MAP3K1	5160
ECSIT	4997
PPP2R1A	4669
UBC	4421
DUSP6	4367
SKP1	4349
MAPKAPK2	4176
MAPK10	4136
JUN	3964
MAPK11	3955
SOCS1	3886
RPS6KA2	3177
TAB3	3165
RPS6KA3	3012
MAP3K7	2453
PPP2R5D	2440
ATF2	2110
UBE2N	1951
MAP2K7	1647
AGER	1309
VRK3	1293
UBA52	1071
RIPK2	1042
ELK1	1040
NKIRAS1	387
NFKBIB	-88
HMGB1	-200
TRAF6	-241
PPP2R1B	-246
MEF2C	-319
NFKB2	-865
MAPK7	-1294
CREB1	-1382
RELA	-1807
DUSP7	-3253
BTRC	-4932
S100B	-5025
IKBKB	-5290
DUSP4	-6432
RPS27A	-6894
MAPK9	-7182
MAPK8	-9646
IRAK2	-9718
SIGIRR	-10688
CUL1	-11467
RPS6KA5	-11616
NOD1	-12234

---

Toll Like Receptor TLR1:TLR2 Cascade

	1243
set	Toll Like Receptor TLR1:TLR2 Cascade
setSize	92
pANOVA	3.67e-13
s.dist	0.438
p.adjustANOVA	1.79e-11

Top enriched genes

GeneID	Gene Rank
S100A12	9567
CD36	9486
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
APP	9123
MAPK3	9078
TLR2	9069
TLR1	9041
MAP2K6	9010
TLR4	8981
MAP2K1	8960
IRAK3	8947
TLR6	8931
LY96	8871
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255

Click HERE to show all gene set members

GeneID	Gene Rank
S100A12	9567
CD36	9486
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
APP	9123
MAPK3	9078
TLR2	9069
TLR1	9041
MAP2K6	9010
TLR4	8981
MAP2K1	8960
IRAK3	8947
TLR6	8931
LY96	8871
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959
RPS6KA1	7800
PPP2CB	7769
PELI3	7736
MAPK1	7520
BTK	7156
TAB2	7070
MAP2K4	6948
NFKBIA	6835
UBB	6737
PELI1	6596
NFKB1	6367
FBXW11	6282
MAP3K8	6262
FOS	6179
IRAK1	6159
ATF1	5790
TAB1	5711
TIRAP	5700
UBE2V1	5681
TNIP2	5630
IKBKG	5434
MAP3K1	5160
ECSIT	4997
PPP2R1A	4669
UBC	4421
DUSP6	4367
SKP1	4349
MAPKAPK2	4176
MAPK10	4136
JUN	3964
MAPK11	3955
SOCS1	3886
RPS6KA2	3177
TAB3	3165
RPS6KA3	3012
MAP3K7	2453
PPP2R5D	2440
ATF2	2110
UBE2N	1951
MAP2K7	1647
AGER	1309
VRK3	1293
UBA52	1071
RIPK2	1042
ELK1	1040
NKIRAS1	387
NFKBIB	-88
HMGB1	-200
TRAF6	-241
PPP2R1B	-246
MEF2C	-319
NFKB2	-865
MAPK7	-1294
CREB1	-1382
RELA	-1807
DUSP7	-3253
BTRC	-4932
S100B	-5025
IKBKB	-5290
DUSP4	-6432
RPS27A	-6894
MAPK9	-7182
MAPK8	-9646
IRAK2	-9718
SIGIRR	-10688
CUL1	-11467
RPS6KA5	-11616
NOD1	-12234

---

Toll Like Receptor TLR6:TLR2 Cascade

	1244
set	Toll Like Receptor TLR6:TLR2 Cascade
setSize	92
pANOVA	3.67e-13
s.dist	0.438
p.adjustANOVA	1.79e-11

Top enriched genes

GeneID	Gene Rank
S100A12	9567
CD36	9486
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
APP	9123
MAPK3	9078
TLR2	9069
TLR1	9041
MAP2K6	9010
TLR4	8981
MAP2K1	8960
IRAK3	8947
TLR6	8931
LY96	8871
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255

Click HERE to show all gene set members

GeneID	Gene Rank
S100A12	9567
CD36	9486
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
APP	9123
MAPK3	9078
TLR2	9069
TLR1	9041
MAP2K6	9010
TLR4	8981
MAP2K1	8960
IRAK3	8947
TLR6	8931
LY96	8871
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959
RPS6KA1	7800
PPP2CB	7769
PELI3	7736
MAPK1	7520
BTK	7156
TAB2	7070
MAP2K4	6948
NFKBIA	6835
UBB	6737
PELI1	6596
NFKB1	6367
FBXW11	6282
MAP3K8	6262
FOS	6179
IRAK1	6159
ATF1	5790
TAB1	5711
TIRAP	5700
UBE2V1	5681
TNIP2	5630
IKBKG	5434
MAP3K1	5160
ECSIT	4997
PPP2R1A	4669
UBC	4421
DUSP6	4367
SKP1	4349
MAPKAPK2	4176
MAPK10	4136
JUN	3964
MAPK11	3955
SOCS1	3886
RPS6KA2	3177
TAB3	3165
RPS6KA3	3012
MAP3K7	2453
PPP2R5D	2440
ATF2	2110
UBE2N	1951
MAP2K7	1647
AGER	1309
VRK3	1293
UBA52	1071
RIPK2	1042
ELK1	1040
NKIRAS1	387
NFKBIB	-88
HMGB1	-200
TRAF6	-241
PPP2R1B	-246
MEF2C	-319
NFKB2	-865
MAPK7	-1294
CREB1	-1382
RELA	-1807
DUSP7	-3253
BTRC	-4932
S100B	-5025
IKBKB	-5290
DUSP4	-6432
RPS27A	-6894
MAPK9	-7182
MAPK8	-9646
IRAK2	-9718
SIGIRR	-10688
CUL1	-11467
RPS6KA5	-11616
NOD1	-12234

---

ER to Golgi Anterograde Transport

	327
set	ER to Golgi Anterograde Transport
setSize	129
pANOVA	4.27e-13
s.dist	0.369
p.adjustANOVA	2.01e-11

Top enriched genes

GeneID	Gene Rank
F5	9524
SPTB	9250
ARF4	9201
SERPINA1	9179
KDELR1	9163
DCTN2	9158
CD55	9157
ARF1	9083
RAB1A	9075
TGFA	9031
CTSZ	9001
ANK1	8897
NSF	8815
CAPZA2	8521
RAB1B	8407
DCTN4	8385
COPA	8319
CAPZA1	8165
SEC24D	8130
CAPZB	8057

Click HERE to show all gene set members

GeneID	Gene Rank
F5	9524
SPTB	9250
ARF4	9201
SERPINA1	9179
KDELR1	9163
DCTN2	9158
CD55	9157
ARF1	9083
RAB1A	9075
TGFA	9031
CTSZ	9001
ANK1	8897
NSF	8815
CAPZA2	8521
RAB1B	8407
DCTN4	8385
COPA	8319
CAPZA1	8165
SEC24D	8130
CAPZB	8057
ARF5	7975
COPB2	7965
TMED7	7909
TRAPPC1	7887
CNIH1	7832
ARF3	7798
SPTA1	7785
SEC24A	7716
ACTR10	7652
COPG2	7636
DYNC1I2	7629
KDELR2	7585
COPG1	7533
SEC23A	7416
COPB1	7399
DCTN6	7382
TFG	7240
TMED9	7199
STX5	7186
LMAN2	7178
TRAPPC3	7158
MCFD2	7136
ACTR1A	7088
LMAN2L	7003
F8	6996
DYNC1LI1	6992
COPE	6979
PPP6C	6887
GORASP1	6670
SAR1B	6562
PREB	6450
COL7A1	6375
GOLGA2	6217
TMED2	6098
DCTN3	6080
DYNLL1	6049
CD59	5964
SEC22B	5939
SEC13	5820
ARCN1	5661
MIA2	5618
TMEM115	5605
AREG	5494
TRAPPC9	5414
PPP6R1	5328
YKT6	5277
TRAPPC5	5253
DCTN1	5143
SEC16A	4687
COG7	4321
DYNC1LI2	4253
DYNC1I1	4211
TRAPPC6B	4201
USO1	4192
NAPG	4190
COPZ1	4081
ARFGAP3	3807
SEC24B	3655
SCFD1	3593
PPP6R3	3323
TMED3	2779
CTSC	2547
CSNK1D	2412
NAPA	1385
SEC31A	1144
CNIH2	727
SEC16B	351
TMED10	328
COG4	15
TBC1D20	-49
GOSR1	-160
COG8	-406
SEC23IP	-469
BET1	-631
GOSR2	-1504
ARFGAP1	-1962
KDELR3	-2154
TRAPPC2L	-2337
SEC24C	-2615
NAPB	-2763
COG5	-3318
SPTBN5	-3449
DYNLL2	-4042
DCTN5	-4140
SEC22C	-4285
GBF1	-4322
ANK3	-4974
SEC22A	-5080
SPTBN2	-5189
COG3	-5230
GOLGB1	-5425
ARFGAP2	-5850
COG6	-5872
ANKRD28	-6311
MIA3	-6330
TRAPPC4	-6836
BET1L	-7385
SPTBN1	-7419
DYNC1H1	-7822
COG2	-8023
TRAPPC2	-8851
CNIH3	-9196
TRAPPC10	-9516
LMAN1	-10699
TRAPPC6A	-10921
STX17	-11009
COPZ2	-11047
SPTAN1	-11438
COG1	-12057

---

Interleukin-1 signaling

	554
set	Interleukin-1 signaling
setSize	98
pANOVA	6.36e-13
s.dist	0.42
p.adjustANOVA	2.89e-11

Top enriched genes

GeneID	Gene Rank
S100A12	9567
IL1RN	9432
IL1R2	9396
NKIRAS2	9308
APP	9123
IL1R1	9030
MAP2K6	9010
MAP2K1	8960
IRAK3	8947
TOLLIP	8668
PSMB7	8535
PSMD4	8498
NOD2	8393
MAP3K3	8349
PSME3	8331
PSMB5	8188
PELI2	8166
MYD88	8091
CHUK	7959
PSMD6	7881

Click HERE to show all gene set members

GeneID	Gene Rank
S100A12	9567
IL1RN	9432
IL1R2	9396
NKIRAS2	9308
APP	9123
IL1R1	9030
MAP2K6	9010
MAP2K1	8960
IRAK3	8947
TOLLIP	8668
PSMB7	8535
PSMD4	8498
NOD2	8393
MAP3K3	8349
PSME3	8331
PSMB5	8188
PELI2	8166
MYD88	8091
CHUK	7959
PSMD6	7881
PELI3	7736
PSMD9	7712
PSMD2	7470
IL1RAP	7349
PSMA1	7346
PSMD1	7283
PSMB3	7265
PSMA7	7174
PSMC1	7096
TAB2	7070
MAP2K4	6948
PSMB6	6927
NFKBIA	6835
UBB	6737
PSMF1	6724
PSMC6	6701
PELI1	6596
PSMD12	6537
NFKB1	6367
PSMD11	6296
FBXW11	6282
MAP3K8	6262
IRAK1	6159
PSMD7	6017
PSMD13	5991
PSMA6	5978
PSMD8	5845
TAB1	5711
UBE2V1	5681
TNIP2	5630
IKBKG	5434
PSMA2	5433
IL1B	4830
PSMD3	4693
SEM1	4436
UBC	4421
SKP1	4349
SQSTM1	4123
PSMB2	4103
RBX1	4039
PSMD5	3507
PSMB1	3422
TAB3	3165
PSMD14	2703
PSMC2	2696
PSMB4	2552
MAP3K7	2453
PSMC3	2018
UBE2N	1951
PSMD10	1646
AGER	1309
UBA52	1071
RIPK2	1042
NKIRAS1	387
NFKBIB	-88
HMGB1	-200
TRAF6	-241
PSMA4	-538
NFKB2	-865
PSMC5	-948
RELA	-1807
PSMB8	-3080
BTRC	-4932
S100B	-5025
IKBKB	-5290
PSMA3	-5314
PSMB10	-5768
PSME4	-6099
PSMA5	-6154
RPS27A	-6894
PSMA8	-7559
PSMC4	-9306
IRAK2	-9718
PSME1	-10138
PSME2	-10415
PSMB9	-11362
CUL1	-11467
NOD1	-12234

---

Major pathway of rRNA processing in the nucleolus and cytosol

	626
set	Major pathway of rRNA processing in the nucleolus and cytosol
setSize	180
pANOVA	1.17e-12
s.dist	-0.307
p.adjustANOVA	5.16e-11

Top enriched genes

GeneID	Gene Rank
LAS1L	-12198
RBM28	-11682
BMS1	-11612
PDCD11	-11549
NOP56	-11502
EXOSC10	-11414
UTP4	-11391
EXOSC8	-11326
DDX47	-11150
WDR46	-11050
NOP14	-10925
EXOSC2	-10865
NOL6	-10847
PELP1	-10841
EXOSC7	-10756
IMP4	-10678
UTP15	-10548
UTP20	-10433
EXOSC9	-10425
NOB1	-10365

Click HERE to show all gene set members

GeneID	Gene Rank
LAS1L	-12198
RBM28	-11682
BMS1	-11612
PDCD11	-11549
NOP56	-11502
EXOSC10	-11414
UTP4	-11391
EXOSC8	-11326
DDX47	-11150
WDR46	-11050
NOP14	-10925
EXOSC2	-10865
NOL6	-10847
PELP1	-10841
EXOSC7	-10756
IMP4	-10678
UTP15	-10548
UTP20	-10433
EXOSC9	-10425
NOB1	-10365
HEATR1	-10256
CSNK1E	-10239
NOL11	-10225
NOL9	-10200
EMG1	-10162
FBL	-10108
RRP9	-10053
NOP58	-10035
EXOSC6	-10009
TEX10	-9856
WDR75	-9808
RPS27	-9651
TSR1	-9633
RPL23A	-9477
NCL	-9396
IMP3	-9295
RPL39L	-8982
RPS20	-8922
KRR1	-8597
RPL3	-8478
GNL3	-8367
RPP25	-8346
DHX37	-8302
RPL35	-8239
RPP30	-8204
RPL13A	-8123
MPHOSPH10	-7881
RPS29	-7794
RPS18	-7641
WDR43	-7562
RPL36A	-7442
RPS11	-7122
RPL12	-7038
RPS19	-7037
RPL30	-6995
PNO1	-6955
SNU13	-6919
RPLP2	-6915
RPS27A	-6894
RPL41	-6877
RPP38	-6855
RPL34	-6807
RPL10A	-6644
RPL26	-6636
WDR3	-6598
RPL32	-6577
RPL10	-6562
RPL14	-6518
RPL21	-6481
RPL37	-6401
RPL27A	-6321
RPS23	-6279
RPL11	-6275
RPS25	-6246
RPL19	-6242
RPS17	-6223
RPSA	-6219
RPS6	-6100
RPL35A	-6080
RPL18A	-6029
RPS12	-5985
RPS4X	-5969
NIP7	-5955
RPL38	-5890
RPL24	-5882
RPS3	-5833
RPS15A	-5695
RPS10	-5686
DCAF13	-5627
NOC4L	-5514
RPS14	-5485
RPS5	-5478
RPL17	-5464
RPL36	-5287
BOP1	-5238
RPP21	-5229
RPL18	-5054
RPS7	-5016
RPL22	-4738
RPP40	-4722
RPS3A	-4702
RPS28	-4647
RPL5	-4631
RPS16	-4570
UTP6	-4523
RPS2	-4509
RPL31	-4507
EXOSC5	-4414
BYSL	-4399
DIS3	-4360
LTV1	-4249
EBNA1BP2	-4176
RPS21	-4115
RPL37A	-4004
FTSJ3	-3954
WDR36	-3840
RIOK1	-3784
RPL7A	-3699
RPS15	-3698
RPL29	-3604
RPL4	-3592
TBL3	-3473
RPL13	-3461
RPL6	-3382
RPL23	-3352
RRP1	-3119
RPL39	-3047
UTP3	-2941
RPL27	-2934
RRP7A	-2826
MTREX	-2653
WDR18	-2407
SNORD3A	-2302
RPS8	-2138
PES1	-2028
RPL7	-2018
RPL9	-1827
UTP14A	-1797
RPS13	-1759
RPL22L1	-1643
UTP14C	-1641
RRP36	-1507
RPL28	-1469
RPS26	-1443
RPL8	-1242
RPLP0	-1054
RPL15	-1017
PWP2	-991
EXOSC1	-976
RCL1	-834
FAU	-402
RPS24	-282
RPS4Y1	-222
RPLP1	-65
RPL36AL	91
EXOSC3	489
DDX52	502
RIOK2	947
UBA52	1071
RPS27L	2117
MPHOSPH6	2244
CSNK1D	2412
SENP3	3029
RPP14	3109
DDX21	3131
C1D	3623
ISG20L2	3845
RPL3L	4539
FCF1	4556
UTP11	4710
DDX49	4940
NOL12	4966
UTP18	5163
WDR12	5287
RPS9	5496
ERI1	5597
RPL26L1	7295
EXOSC4	7781
RIOK3	8755
XRN2	9415

---

Diseases of signal transduction by growth factor receptors and second messengers

	298
set	Diseases of signal transduction by growth factor receptors and second messengers
setSize	343
pANOVA	1.26e-12
s.dist	0.223
p.adjustANOVA	5.36e-11

Top enriched genes

GeneID	Gene Rank
FZD5	9561
GRB2	9320
KREMEN1	9259
NCSTN	9139
MAPK3	9078
FKBP1A	9066
PIK3CB	9065
HDAC4	9057
PAPSS1	9039
TGFA	9031
KL	9019
AGTRAP	8987
MAML3	8965
MAP2K1	8960
QKI	8951
ITGA2B	8942
CUX1	8905
ERLIN2	8899
HGF	8856
APBB1IP	8849

Click HERE to show all gene set members

GeneID	Gene Rank
FZD5	9561
GRB2	9320
KREMEN1	9259
NCSTN	9139
MAPK3	9078
FKBP1A	9066
PIK3CB	9065
HDAC4	9057
PAPSS1	9039
TGFA	9031
KL	9019
AGTRAP	8987
MAML3	8965
MAP2K1	8960
QKI	8951
ITGA2B	8942
CUX1	8905
ERLIN2	8899
HGF	8856
APBB1IP	8849
OS9	8845
MARK3	8774
RBPJ	8744
FOXO3	8729
RAC1	8720
ADAM10	8705
JAG1	8661
TLN1	8554
RHOG	8544
PSMB7	8535
ARRB2	8517
PTEN	8516
PSMD4	8498
BAG4	8384
AP3B1	8377
ITGB3	8367
PSME3	8331
IRS2	8323
PPP2CA	8308
FN1	8294
EGF	8267
IQGAP1	8189
PSMB5	8188
STAT3	8152
PTPN12	8125
GAB2	8100
ATG7	8065
VAV1	8021
RAF1	7991
TBL1X	7984
ADAM17	7980
CHUK	7959
NCOR2	7948
FGFR1OP2	7920
AKT1S1	7902
PSMD6	7881
PSEN1	7843
PIK3AP1	7836
CSNK1A1	7813
GSK3A	7811
CASP9	7784
PPP2CB	7769
LYN	7728
PSMD9	7712
MAP3K11	7707
POLR2E	7660
CBL	7599
MAPK1	7520
PSMD2	7470
VCL	7380
SHOC2	7365
PSMA1	7346
BCL2L11	7326
RAP1A	7319
PSMD1	7283
PSMB3	7265
PSMA7	7174
PSMC1	7096
PPP1CB	7093
STAT5B	7011
BAD	7002
STAT5A	6983
VCP	6955
PSMB6	6927
KDM7A	6926
SPRED2	6917
MAP2K2	6906
PPP2R5B	6870
SEL1L	6834
POLR2J	6769
UBB	6737
PSMF1	6724
GSK3B	6720
PSMC6	6701
VWF	6607
PSMD12	6537
FOXO4	6493
CTNNB1	6463
YWHAB	6398
PPP1CC	6334
PSMD11	6296
AGGF1	6284
APH1B	6248
PDPK1	6209
EP300	6208
LRRFIP1	6127
PIK3CD	6096
HDAC7	6070
PSMD7	6017
PDGFRA	6002
PSMD13	5991
PPP2R5A	5985
NCOR1	5979
PSMA6	5978
PSMD8	5845
PSENEN	5833
BIN2	5796
GAB1	5723
HDAC2	5569
GTF2F2	5503
AREG	5494
PDGFA	5484
MAML1	5447
PSMA2	5433
NRAS	5411
FXR1	5385
PTPN11	5383
POLR2L	5362
BRAP	5352
CSK	5285
SNW1	5255
RAC2	5238
ETV6	5219
TGFB1	5201
MAPKAP1	5130
TRAK1	5063
PIK3R2	5051
GTF2F1	5042
FAM114A2	5026
SMAD2	4939
HBEGF	4878
HDAC11	4790
HDAC5	4761
HDAC3	4734
NOTCH1	4733
PIK3CA	4697
PSMD3	4693
PPP2R1A	4669
POLR2F	4646
TBL1XR1	4627
CDKN1A	4438
SEM1	4436
UBC	4421
DUSP6	4367
SKP1	4349
LRP5	4241
APH1A	4198
MDM2	4179
SHC1	4173
CTBP2	4142
CDC37	4125
KSR1	4113
PSMB2	4103
RBX1	4039
NRG1	4018
SND1	3911
TGFBR2	3881
LMNA	3863
TRIM24	3824
KRAS	3760
STRN	3758
KIAA1549	3668
FGF2	3660
AKT1	3656
POLR2G	3581
PSMD5	3507
CREBBP	3460
PSMB1	3422
ZMYM2	3405
RAP1B	3331
APC	3284
HDAC8	3141
NF1	3113
DERL2	3093
PSMD14	2703
PSMC2	2696
ARAF	2680
JAK2	2599
EPGN	2579
PSMB4	2552
PPP2R5D	2440
MYC	2367
HDAC10	2302
CLCN6	2278
ARRB1	2098
PSMC3	2018
EREG	1906
CAMK2G	1888
CCNC	1883
IRS1	1806
PSMD10	1646
TGFBR1	1642
POLR2C	1531
HSP90AA1	1348
HDAC9	1347
BRAF	1314
UBA52	1071
SYVN1	997
LRP6	787
ERLEC1	775
RPS6KB2	652
HDAC1	394
AKT2	345
KREMEN2	321
POLR2I	316
MLST8	304
CD86	-71
PPP2R1B	-246
ERBB3	-468
MAML2	-476
TNKS2	-512
PSMA4	-538
ERBIN	-585
PPP2R5E	-627
TSC2	-804
FAM131B	-831
PSMC5	-948
CREB1	-1382
DUSP10	-1587
POLR2K	-1792
NRG4	-1939
CDK8	-1997
CALM1	-2048
KAT2B	-2393
POLR2B	-2536
NEURL1B	-2658
POLR2H	-2817
FGFR4	-2892
MIB1	-2999
PHB	-3050
PSMB8	-3080
POLR2A	-3105
DUSP7	-3253
HRAS	-3335
KSR2	-3364
FRS2	-3430
CD19	-3769
KANK1	-3909
MYO18A	-3939
FGF7	-3999
POLR2D	-4058
GOLGA4	-4063
CNKSR2	-4481
MAMLD1	-4791
AKAP9	-5065
PSMA3	-5314
FGFR1	-5335
TCF7L2	-5419
SOS1	-5714
PSMB10	-5768
MRAS	-5840
NCBP1	-5866
CPSF6	-5963
PSME4	-6099
PSMA5	-6154
FZD6	-6395
FOXO6	-6467
CTBP1	-6549
DUSP16	-6652
FBXW7	-6709
NR4A1	-6762
CNTRL	-6773
FGFR1OP	-6804
CD80	-6837
FGF23	-6840
CNKSR1	-6858
RPS27A	-6894
SPRED3	-6979
TRAT1	-7043
BCR	-7186
FZD8	-7237
PSMA8	-7559
ZFYVE9	-7706
HES1	-7731
PSEN2	-7844
FIP1L1	-8076
SMAD4	-8273
CDKN1B	-8305
HDAC6	-8348
PDGFB	-8575
SPRED1	-8664
FGF22	-8733
TNKS	-8839
ICOS	-8862
FGF9	-8873
SRC	-9011
HHAT	-9053
FOXO1	-9173
ESR1	-9230
ESR2	-9236
PSMC4	-9306
RICTOR	-9593
NCBP2	-9624
PIK3R1	-9725
CD28	-9858
HEY2	-9918
MTOR	-9948
PORCN	-9992
PSME1	-10138
ZC3HAV1	-10197
AXIN1	-10310
KAT2A	-10374
PSME2	-10415
PLCG1	-10473
MPRIP	-10647
KIT	-11031
MIB2	-11044
AMER1	-11097
TENT4A	-11171
JAG2	-11198
PEBP1	-11270
PSMB9	-11362
PPP2R5C	-11413
NEURL1	-11443
PDGFRB	-11452
CUL1	-11467
LCK	-11492
SMAD3	-11541
DUSP8	-11604
WDR48	-11633
CAMK2D	-11728
FZD4	-11733
FGFR2	-11753
FYN	-11758
STAT1	-11769
AKT3	-11804
DLL1	-11843
PRR5	-11948
PIK3R3	-12037
RNF43	-12040
AGK	-12045
YES1	-12143
ERBB2	-12281

---

Clathrin-mediated endocytosis

	191
set	Clathrin-mediated endocytosis
setSize	127
pANOVA	3.18e-12
s.dist	0.358
p.adjustANOVA	1.32e-10

Top enriched genes

GeneID	Gene Rank
VAMP7	9549
GRB2	9320
AGFG1	9261
ITSN1	9186
CLTC	9056
PICALM	9052
TGFA	9031
CLTCL1	8939
ARPC1A	8923
AMPH	8875
RAB5C	8688
AP2M1	8673
FNBP1L	8672
ARPC5	8653
TGOLN2	8647
ARRB2	8517
HIP1	8445
CLTA	8402
ARPC3	8309
REPS2	8273

Click HERE to show all gene set members

GeneID	Gene Rank
VAMP7	9549
GRB2	9320
AGFG1	9261
ITSN1	9186
CLTC	9056
PICALM	9052
TGFA	9031
CLTCL1	8939
ARPC1A	8923
AMPH	8875
RAB5C	8688
AP2M1	8673
FNBP1L	8672
ARPC5	8653
TGOLN2	8647
ARRB2	8517
HIP1	8445
CLTA	8402
ARPC3	8309
REPS2	8273
EGF	8267
DAB2	8259
PACSIN2	8208
VAMP3	8121
TOR1A	8085
AP2S1	8080
EPN1	8026
ACTR3	7888
ACTR2	7827
FCHO2	7762
SH3GL1	7733
ARPC4	7605
CBL	7599
ARPC2	7449
AP2A2	7360
IGF2R	7270
DNM3	7167
RAB5A	7166
SNX18	7107
GAPVD1	6866
RAB5B	6801
UBB	6737
COPS7A	6649
AP2A1	6628
NEDD8	6597
GRK3	6469
OCRL	6436
LDLR	6329
SYNJ1	6310
SH3KBP1	6227
CLTB	6195
STAM2	6183
DNM2	6163
COPS2	6147
GRK2	6141
COPS3	6040
UBQLN2	6009
CTTN	5999
AREG	5494
VAMP8	5284
UBQLN1	5164
SYT1	5162
ITSN2	5108
SCARB2	4979
HBEGF	4878
DNAJC6	4706
HGS	4570
UBC	4421
COPS5	4415
EPS15	4189
STON2	3698
EPS15L1	3688
DNM1	3526
PIP5K1C	3436
NECAP2	3428
KIAA0319	3373
VAMP4	3236
CFTR	2738
STON1	2624
GAK	2606
EPGN	2579
TRIP10	2267
NECAP1	2247
ARRB1	2098
EREG	1906
COPS4	1865
COPS6	1663
TFRC	1578
ARF6	1407
STAM	1299
LRP2	1222
TF	1172
UBA52	1071
SYT2	451
AVPR2	306
WASL	283
FNBP1	-320
SNX9	-404
TOR1B	-1930
ARFGAP1	-1962
FCHO1	-2036
AP2B1	-2748
EPN2	-3979
GPS1	-4577
PIK3C2A	-5233
CD4	-5320
SYT11	-6617
RPS27A	-6894
REPS1	-7232
SYNJ2	-8530
M6PR	-8665
COPS8	-8868
LDLRAP1	-8898
AAK1	-9323
COPS7B	-9938
HIP1R	-10052
IL7R	-10324
DVL2	-10753
HSPA8	-10913
CD3D	-11094
BIN1	-11183
CD3G	-11409
VAMP2	-11692
FZD4	-11733
SLC2A8	-11810
ADRB2	-11879
PACSIN1	-12327

---

Signaling by Rho GTPases

	1133
set	Signaling by Rho GTPases
setSize	367
pANOVA	4.55e-12
s.dist	0.21
p.adjustANOVA	1.82e-10

Top enriched genes

GeneID	Gene Rank
WASF1	9568
S100A9	9562
S100A8	9560
H2AJ	9418
H2BC21	9368
NCF4	9365
ARHGEF11	9346
RHOT1	9337
GRB2	9320
YWHAG	9310
ARPC1B	9303
CYFIP1	9270
CTNNA1	9237
MAPK14	9219
NCF2	9209
ITSN1	9186
H2BC12	9178
MAPK3	9078
DLG4	9070
ACTB	9060

Click HERE to show all gene set members

GeneID	Gene Rank
WASF1	9568.0
S100A9	9562.0
S100A8	9560.0
H2AJ	9418.0
H2BC21	9368.0
NCF4	9365.0
ARHGEF11	9346.0
RHOT1	9337.0
GRB2	9320.0
YWHAG	9310.0
ARPC1B	9303.0
CYFIP1	9270.0
CTNNA1	9237.0
MAPK14	9219.0
NCF2	9209.0
ITSN1	9186.0
H2BC12	9178.0
MAPK3	9078.0
DLG4	9070.0
ACTB	9060.0
PRKCD	9012.0
YWHAE	9009.0
CYBB	9000.0
RHOU	8950.0
ARPC1A	8923.0
ARHGAP18	8883.0
ARHGEF40	8800.0
FGD4	8799.0
H3-3A	8754.0
RAC1	8720.0
ARHGDIB	8708.0
MYL6	8687.0
ACTG1	8671.0
ARPC5	8653.0
YWHAH	8621.0
WAS	8596.0
RHOG	8544.0
DLC1	8527.0
CLIP1	8474.0
ARHGAP26	8415.0
MRTFA	8376.0
WASF2	8373.0
DIAPH2	8365.0
SOS2	8350.0
TAX1BP3	8343.0
ARPC3	8309.0
PPP2CA	8308.0
B9D2	8262.0
PAK1	8252.0
ARAP3	8243.0
CFL1	8242.0
PAK2	8226.0
RHOA	8218.0
LIMK2	8190.0
IQGAP1	8189.0
H2BC5	8163.0
KIF5B	8144.0
RHOBTB1	8077.0
H2BC11	8076.0
H2AC6	8070.0
VAV1	8021.0
GMIP	7917.0
ACTR3	7888.0
ARHGAP29	7864.0
ACTR2	7827.0
ARAP1	7825.0
ARHGAP19	7799.0
PPP2CB	7769.0
NDEL1	7753.0
MYL9	7719.0
MAPRE1	7700.0
DYNC1I2	7629.0
ARPC4	7605.0
NCKAP1	7562.0
H2BC4	7549.0
CDC42	7539.0
MAPK1	7520.0
NCKAP1L	7516.0
ARHGAP6	7514.0
RHOQ	7504.0
H2BC17	7502.0
ARHGAP24	7497.0
PLEKHG2	7493.0
KLC3	7479.0
ARPC2	7449.0
ROCK1	7445.0
NCF1	7433.0
FAM13A	7392.0
GDI2	7337.0
SRF	7205.0
BTK	7156.0
ABI1	7154.0
PPP1CB	7093.0
BRK1	7085.0
PRKCB	7056.0
PPP1R14A	7009.0
DYNC1LI1	6992.0
CYBA	6952.0
ARHGEF17	6919.0
WASF3	6915.0
RALBP1	6894.0
PPP2R5B	6870.0
H3C15	6780.5
MYH9	6772.0
SRGAP1	6726.0
MYLK	6690.0
ARHGEF2	6647.0
PREX1	6513.0
MYO9B	6481.0
CTNNB1	6463.0
OCRL	6436.0
YWHAB	6398.0
PPP1CC	6334.0
ARHGAP9	6288.0
IQGAP2	6286.0
PDPK1	6209.0
ABR	6165.0
ARHGDIA	6155.0
ROCK2	6151.0
PPP1R12A	6131.0
H2AZ1	6126.0
ARHGEF37	6112.0
DYNLL1	6049.0
CTTN	5999.0
PPP2R5A	5985.0
GNA13	5903.0
ARHGAP27	5890.0
SRGAP2	5824.0
SEC13	5820.0
GDI1	5807.0
WIPF2	5769.0
DVL3	5734.0
YWHAZ	5687.0
KLC1	5596.0
ECT2	5587.0
PFN1	5562.0
ARHGAP23	5543.0
PAFAH1B1	5534.0
TAOK1	5471.0
H2BC9	5461.0
H2BC15	5458.0
ARHGAP31	5445.0
NSL1	5429.0
RAC2	5238.0
MYL12B	5177.0
ARHGAP30	5105.0
PIK3R2	5051.0
H2AC20	5039.0
ARHGAP21	5034.0
CDC25C	5024.0
VAV3	4974.0
CHN2	4944.0
AR	4913.0
LIMK1	4741.0
PPP2R1A	4669.0
ARHGAP1	4662.0
FGD2	4526.0
PTK2	4506.0
DIAPH3	4446.0
CENPA	4259.0
DYNC1LI2	4253.0
DYNC1I1	4211.0
FMNL1	4191.0
CDC20	4087.0
BIRC5	4082.0
MAPK11	3955.0
STARD8	3858.0
DAAM1	3591.0
IQGAP3	3509.0
AKAP13	3430.0
FGD3	3417.0
BUB1	3411.0
PMF1	3407.0
KIF14	3370.0
KTN1	3322.0
STARD13	3273.0
ARHGEF12	3230.0
NUP37	3153.0
NUP98	3124.0
BUB1B	3104.0
KLK2	3082.0
PLK1	3065.0
RACGAP1	2921.0
CENPF	2876.0
ARHGAP28	2800.0
SKA1	2798.0
CFTR	2738.0
ARHGAP32	2659.0
NDE1	2635.0
ARHGEF6	2483.0
PPP2R5D	2440.0
SPC24	2393.0
TRIP10	2267.0
MCF2	2087.0
TRIO	1829.0
DEPDC1B	1822.0
PPP1R12B	1737.0
ARHGAP11A	1723.0
PIK3C3	1626.0
SFN	1557.0
ARHGAP22	1541.0
ARHGAP4	1202.0
RHOB	1190.0
PRKCA	1163.0
PRC1	1119.0
NCOA2	1109.0
DEPDC7	971.0
AURKB	959.0
KIF2C	812.0
CENPE	741.0
TIAM1	701.0
MYH10	663.0
WIPF1	581.0
FLNA	547.0
NCKIPSD	320.0
WASL	283.0
ABL1	229.0
ARHGAP15	215.0
PKN2	151.0
DVL1	61.0
ZW10	37.0
CENPN	24.0
ITGB1	-50.0
BAIAP2	-179.0
PPP2R1B	-246.0
KNL1	-360.0
ERCC6L	-418.0
SYDE2	-491.0
CLASP1	-573.0
PPP2R5E	-627.0
NUDC	-674.0
DIAPH1	-704.0
RANBP2	-808.0
OPHN1	-952.0
KIF2A	-1080.0
ARHGAP44	-1179.0
XPO1	-1199.0
H2AZ2	-1266.0
AHCTF1	-1621.0
CDCA8	-1850.0
PKN1	-1986.0
CALM1	-2048.0
CLASP2	-2169.0
PFN2	-2375.0
KIF18A	-2744.0
NUP85	-3077.0
CENPI	-3165.0
ARHGEF38	-3267.0
PIN1	-3272.0
RAC3	-3292.0
SGO2	-3359.0
ARHGAP35	-3408.0
MYH11	-3490.0
PKN3	-3714.0
KALRN	-3725.0
FMNL2	-3776.0
ARHGEF26	-3778.0
LIN7B	-3872.0
ARHGEF4	-3912.0
PIK3R4	-4040.0
DYNLL2	-4042.0
ARHGEF10	-4043.0
VAV2	-4073.0
PAK3	-4194.0
NUF2	-4325.0
RHPN2	-4434.0
ARHGEF35	-4546.0
ARHGEF7	-4627.0
ZWINT	-4758.0
RHPN1	-4792.0
CIT	-5008.0
MAD1L1	-5035.0
RCC2	-5199.0
CENPO	-5215.0
CENPM	-5373.0
RHOT2	-5408.0
ARHGAP33	-5429.0
ARHGEF1	-5462.0
NOXA1	-5532.0
RHOBTB2	-5623.0
SOS1	-5714.0
SRGAP3	-5738.0
SEH1L	-5957.0
OBSCN	-6026.0
INCENP	-6043.0
ARHGEF10L	-6066.0
CKAP5	-6299.0
ARHGEF5	-6441.0
CENPQ	-6451.0
CENPU	-6495.0
H2BU1	-6519.0
NF2	-6614.0
ARHGEF18	-6672.0
SGO1	-6826.0
INPP5B	-6905.0
BCR	-7186.0
ARHGAP39	-7429.0
YWHAQ	-7471.0
NET1	-7542.0
ITGB3BP	-7623.0
ARHGAP12	-7661.0
ARHGAP42	-7711.0
ARHGAP11B	-7750.0
SCAI	-7817.0
DYNC1H1	-7822.0
NUP133	-7839.0
ARHGAP17	-7883.0
KNTC1	-7922.0
MCF2L	-7933.0
CHN1	-8061.0
PLEKHG5	-8069.0
MAD2L1	-8081.0
KLC4	-8231.0
MEN1	-8265.0
CDKN1B	-8305.0
KIF5A	-8378.0
CENPK	-8469.0
ARHGAP25	-8588.0
ARHGEF19	-8700.0
KLC2	-8724.0
CENPH	-8745.0
ARHGAP5	-8857.0
ARHGAP10	-8936.0
SKA2	-8943.0
SRC	-9011.0
NDC80	-9117.0
CENPT	-9416.0
KDM1A	-9476.0
RASGRF2	-9554.0
NUP43	-9595.0
MYO9A	-9616.0
RPS27	-9651.0
GOPC	-9696.0
A2M	-9822.0
NUP160	-10383.0
CYFIP2	-10387.0
RHOH	-10460.0
MIS12	-10502.0
KDM4C	-10513.0
NUP107	-10570.0
FAM13B	-10669.0
DVL2	-10753.0
ABI2	-10893.0
DSN1	-10945.0
ARHGEF39	-11011.0
TIAM2	-11149.0
SPDL1	-11264.0
RHOC	-11333.0
PPP2R5C	-11413.0
NCK1	-11488.0
PRKCZ	-11508.0
CDH1	-11512.0
BUB3	-11546.0
RANGAP1	-11665.0
ZWILCH	-11800.0
CENPL	-11807.0
CENPP	-11863.0
FMNL3	-11869.0
CENPC	-11902.0
ARAP2	-12011.0
EVL	-12046.0
ARHGEF3	-12048.0
TAGAP	-12171.0
RTKN	-12215.0
ARHGEF9	-12232.0
ARHGAP8	-12256.0
RHOF	-12291.0

---

Interleukin-1 family signaling

	553
set	Interleukin-1 family signaling
setSize	125
pANOVA	1.1e-11
s.dist	0.352
p.adjustANOVA	4.29e-10

Top enriched genes

GeneID	Gene Rank
S100A12	9567
IL1RN	9432
IL1R2	9396
NKIRAS2	9308
APP	9123
ALOX5	9088
IL1R1	9030
MAP2K6	9010
MAP2K1	8960
IRAK3	8947
TOLLIP	8668
PSMB7	8535
PSMD4	8498
NOD2	8393
MAP3K3	8349
PSME3	8331
PSMB5	8188
PELI2	8166
STAT3	8152
PTPN12	8125

Click HERE to show all gene set members

GeneID	Gene Rank
S100A12	9567
IL1RN	9432
IL1R2	9396
NKIRAS2	9308
APP	9123
ALOX5	9088
IL1R1	9030
MAP2K6	9010
MAP2K1	8960
IRAK3	8947
TOLLIP	8668
PSMB7	8535
PSMD4	8498
NOD2	8393
MAP3K3	8349
PSME3	8331
PSMB5	8188
PELI2	8166
STAT3	8152
PTPN12	8125
MYD88	8091
CHUK	7959
PSMD6	7881
PELI3	7736
PSMD9	7712
PTPN2	7634
PSMD2	7470
IL18	7395
IL1RAP	7349
PSMA1	7346
PSMD1	7283
PSMB3	7265
PSMA7	7174
PSMC1	7096
TAB2	7070
MAP2K4	6948
PSMB6	6927
NFKBIA	6835
UBB	6737
PSMF1	6724
PSMC6	6701
PTPN9	6633
PELI1	6596
PSMD12	6537
NFKB1	6367
PSMD11	6296
FBXW11	6282
MAP3K8	6262
PTPN6	6176
IRAK1	6159
PSMD7	6017
PSMD13	5991
PSMA6	5978
PTPN18	5944
PSMD8	5845
TAB1	5711
UBE2V1	5681
TNIP2	5630
IKBKG	5434
PSMA2	5433
PTPN11	5383
CTSG	5224
IL1B	4830
PSMD3	4693
SEM1	4436
UBC	4421
SKP1	4349
IL18R1	4330
SQSTM1	4123
PSMB2	4103
CASP1	4086
RBX1	4039
PSMD5	3507
PSMB1	3422
TAB3	3165
TBK1	3159
PSMD14	2703
PSMC2	2696
IL1RL1	2644
PSMB4	2552
MAP3K7	2453
PSMC3	2018
UBE2N	1951
PSMD10	1646
AGER	1309
IL18RAP	1270
UBA52	1071
RIPK2	1042
IL33	392
NKIRAS1	387
NFKBIB	-88
HMGB1	-200
TRAF6	-241
PSMA4	-538
NFKB2	-865
PSMC5	-948
PTPN23	-1197
RELA	-1807
PTPN14	-2421
PSMB8	-3080
PTPN20	-3554
BTRC	-4932
S100B	-5025
IKBKB	-5290
PSMA3	-5314
PSMB10	-5768
PSME4	-6099
PSMA5	-6154
RPS27A	-6894
PSMA8	-7559
PSMC4	-9306
MAPK8	-9646
IRAK2	-9718
PSME1	-10138
PTPN13	-10143
IL4	-10166
PSME2	-10415
SIGIRR	-10688
IL18BP	-10728
PTPN7	-11022
PSMB9	-11362
CUL1	-11467
SMAD3	-11541
PTPN4	-12133
NOD1	-12234

---

Signaling by NTRKs

	1120
set	Signaling by NTRKs
setSize	116
pANOVA	1.21e-11
s.dist	0.364
p.adjustANOVA	4.6e-10

Top enriched genes

GeneID	Gene Rank
DUSP3	9324
GRB2	9320
MAPK14	9219
RIT1	9174
FURIN	9162
MAPK3	9078
PIK3CB	9065
CLTC	9056
MAP2K1	8960
CRK	8941
FOSL1	8911
PCSK6	8824
RAC1	8720
AP2M1	8673
CDK5	8663
RALB	8475
CLTA	8402
IRS2	8323
LYL1	8321
PPP2CA	8308

Click HERE to show all gene set members

GeneID	Gene Rank
DUSP3	9324
GRB2	9320
MAPK14	9219
RIT1	9174
FURIN	9162
MAPK3	9078
PIK3CB	9065
CLTC	9056
MAP2K1	8960
CRK	8941
FOSL1	8911
PCSK6	8824
RAC1	8720
AP2M1	8673
CDK5	8663
RALB	8475
CLTA	8402
IRS2	8323
LYL1	8321
PPP2CA	8308
MAPKAPK3	8255
RHOA	8218
STAT3	8152
AP2S1	8080
MEF2A	8030
RPS6KA1	7800
PPP2CB	7769
TRIB1	7725
MAPK1	7520
FRS3	7402
AP2A2	7360
RAP1A	7319
SRF	7205
DNM3	7167
KIDINS220	7111
MAP2K2	6906
JUNB	6889
AP2A1	6628
YWHAB	6398
EP300	6208
FOS	6179
DNM2	6163
BAX	5996
ATF1	5790
GAB1	5723
NRAS	5411
PTPN11	5383
PIK3R2	5051
PCSK5	4881
ID1	4819
PIK3CA	4697
PPP2R1A	4669
SGK1	4642
SHC2	4499
DUSP6	4367
MAPKAPK2	4176
SHC1	4173
SHC3	4054
CRKL	3986
MAP2K5	3957
MAPK11	3955
KRAS	3760
MAPK13	3704
DNM1	3526
DNAL4	3391
ADORA2A	3227
RPS6KA2	3177
NTRK3	3038
RPS6KA3	3012
EGR1	2965
RALA	2686
PTPRO	2485
PPP2R5D	2440
ATF2	2110
IRS1	1806
JUND	1561
FOSB	1432
NAB1	1315
BRAF	1314
VRK3	1293
TF	1172
ELK1	1040
REST	945
TIAM1	701
NELFB	385
PPP2R1B	-246
MEF2C	-319
EGR3	-690
MAPK12	-946
CDK5R1	-1166
TCF12	-1268
MAPK7	-1294
CREB1	-1382
EGR2	-2130
AP2B1	-2748
MEF2D	-3132
DUSP7	-3253
HRAS	-3335
FRS2	-3430
DOCK3	-4198
CHD4	-4576
SOS1	-5714
DUSP4	-6432
NTRK1	-7791
ID3	-8629
TPH1	-8787
SRC	-9011
PIK3R1	-9725
RAPGEF1	-10033
NAB2	-10348
PLCG1	-10473
ID2	-11019
RPS6KA5	-11616
FYN	-11758
RALGDS	-12117
PTPRS	-12262

---

TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation

	1213
set	TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
setSize	88
pANOVA	1.75e-11
s.dist	0.415
p.adjustANOVA	6.45e-10

Top enriched genes

GeneID	Gene Rank
S100A12	9567
TLR8	9335
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
APP	9123
MAPK3	9078
MAP2K6	9010
TLR4	8981
MAP2K1	8960
LY96	8871
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959

Click HERE to show all gene set members

GeneID	Gene Rank
S100A12	9567
TLR8	9335
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
APP	9123
MAPK3	9078
MAP2K6	9010
TLR4	8981
MAP2K1	8960
LY96	8871
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959
RPS6KA1	7800
PPP2CB	7769
PELI3	7736
MAPK1	7520
TAB2	7070
MAP2K4	6948
NFKBIA	6835
UBB	6737
PELI1	6596
TICAM1	6380
NFKB1	6367
FBXW11	6282
MAP3K8	6262
TICAM2	6244
FOS	6179
IRAK1	6159
ATF1	5790
TAB1	5711
UBE2V1	5681
TNIP2	5630
IKBKG	5434
MAP3K1	5160
ECSIT	4997
PPP2R1A	4669
UBC	4421
DUSP6	4367
SKP1	4349
MAPKAPK2	4176
MAPK10	4136
JUN	3964
MAPK11	3955
RPS6KA2	3177
TAB3	3165
RPS6KA3	3012
MAP3K7	2453
PPP2R5D	2440
ATF2	2110
UBE2N	1951
MAP2K7	1647
AGER	1309
VRK3	1293
UBA52	1071
RIPK2	1042
ELK1	1040
NKIRAS1	387
NFKBIB	-88
HMGB1	-200
TRAF6	-241
PPP2R1B	-246
MEF2C	-319
TLR7	-655
NFKB2	-865
MAPK7	-1294
CREB1	-1382
RELA	-1807
DUSP7	-3253
BTRC	-4932
S100B	-5025
IKBKB	-5290
TLR9	-5909
DUSP4	-6432
RPS27A	-6894
MAPK9	-7182
MAPK8	-9646
IRAK2	-9718
CUL1	-11467
RPS6KA5	-11616
NOD1	-12234

---

Antigen processing-Cross presentation

	75
set	Antigen processing-Cross presentation
setSize	98
pANOVA	2.1e-11
s.dist	0.391
p.adjustANOVA	7.55e-10

Top enriched genes

GeneID	Gene Rank
CD36	9486
FCGR1A	9397
NCF4	9365
NCF2	9209
FCGR1B	9168
CD14	9164
TLR2	9069
TLR1	9041
CYBB	9000
TLR4	8981
TLR6	8931
LY96	8871
SNAP23	8578
PSMB7	8535
PSMD4	8498
PSME3	8331
CTSS	8300
PSMB5	8188
VAMP3	8121
MYD88	8091

Click HERE to show all gene set members

GeneID	Gene Rank
CD36	9486
FCGR1A	9397
NCF4	9365
NCF2	9209
FCGR1B	9168
CD14	9164
TLR2	9069
TLR1	9041
CYBB	9000
TLR4	8981
TLR6	8931
LY96	8871
SNAP23	8578
PSMB7	8535
PSMD4	8498
PSME3	8331
CTSS	8300
PSMB5	8188
VAMP3	8121
MYD88	8091
CHUK	7959
PSMD6	7881
PSMD9	7712
PSMD2	7470
NCF1	7433
PSMA1	7346
PSMD1	7283
PSMB3	7265
PSMA7	7174
BTK	7156
SEC61B	7125
PSMC1	7096
ITGB5	7004
CYBA	6952
PSMB6	6927
UBB	6737
PSMF1	6724
PSMC6	6701
PSMD12	6537
SEC61A1	6517
CALR	6415
PSMD11	6296
ITGAV	6133
PSMD7	6017
PSMD13	5991
PSMA6	5978
SEC22B	5939
PSMD8	5845
TIRAP	5700
IKBKG	5434
PSMA2	5433
VAMP8	5284
SEC61G	4837
PSMD3	4693
CTSL	4583
SEM1	4436
UBC	4421
PDIA3	4172
PSMB2	4103
PSMD5	3507
PSMB1	3422
MRC1	3187
TAPBP	3075
PSMD14	2703
PSMC2	2696
PSMB4	2552
PSMC3	2018
PSMD10	1646
UBA52	1071
HLA-C	1032
HLA-B	658
STX4	626
MRC2	-90
PSMA4	-538
PSMC5	-948
HLA-G	-2370
HLA-A	-2578
CTSV	-2816
PSMB8	-3080
HLA-H	-3892
HLA-E	-4448
IKBKB	-5290
PSMA3	-5314
PSMB10	-5768
PSME4	-6099
PSMA5	-6154
RPS27A	-6894
B2M	-7019
PSMA8	-7559
PSMC4	-9306
LNPEP	-9853
PSME1	-10138
PSME2	-10415
TAP1	-10727
HLA-F	-10771
SEC61A2	-10873
PSMB9	-11362
TAP2	-11828

---

Transport to the Golgi and subsequent modification

	1292
set	Transport to the Golgi and subsequent modification
setSize	155
pANOVA	2.18e-11
s.dist	0.311
p.adjustANOVA	7.63e-10

Top enriched genes

GeneID	Gene Rank
F5	9524
SPTB	9250
ARF4	9201
SERPINA1	9179
KDELR1	9163
DCTN2	9158
CD55	9157
ARF1	9083
RAB1A	9075
TGFA	9031
CTSZ	9001
B4GALT5	8909
ANK1	8897
NSF	8815
MGAT4B	8742
CAPZA2	8521
RAB1B	8407
DCTN4	8385
COPA	8319
CAPZA1	8165

Click HERE to show all gene set members

GeneID	Gene Rank
F5	9524
SPTB	9250
ARF4	9201
SERPINA1	9179
KDELR1	9163
DCTN2	9158
CD55	9157
ARF1	9083
RAB1A	9075
TGFA	9031
CTSZ	9001
B4GALT5	8909
ANK1	8897
NSF	8815
MGAT4B	8742
CAPZA2	8521
RAB1B	8407
DCTN4	8385
COPA	8319
CAPZA1	8165
SEC24D	8130
CAPZB	8057
MAN1A1	7979
ARF5	7975
COPB2	7965
TMED7	7909
TRAPPC1	7887
CNIH1	7832
ARF3	7798
SPTA1	7785
SEC24A	7716
ACTR10	7652
COPG2	7636
DYNC1I2	7629
KDELR2	7585
COPG1	7533
FUCA1	7508
SEC23A	7416
COPB1	7399
DCTN6	7382
TFG	7240
TMED9	7199
STX5	7186
LMAN2	7178
TRAPPC3	7158
MCFD2	7136
ACTR1A	7088
LMAN2L	7003
F8	6996
DYNC1LI1	6992
COPE	6979
PPP6C	6887
GORASP1	6670
MAN2A2	6669
SAR1B	6562
PREB	6450
COL7A1	6375
GOLGA2	6217
MGAT1	6190
TMED2	6098
DCTN3	6080
DYNLL1	6049
CHST8	6024
CD59	5964
SEC22B	5939
ST3GAL4	5930
SEC13	5820
ARCN1	5661
MIA2	5618
TMEM115	5605
AREG	5494
TRAPPC9	5414
PPP6R1	5328
YKT6	5277
TRAPPC5	5253
DCTN1	5143
SEC16A	4687
B4GALT1	4354
COG7	4321
DYNC1LI2	4253
DYNC1I1	4211
TRAPPC6B	4201
USO1	4192
NAPG	4190
COPZ1	4081
ARFGAP3	3807
SEC24B	3655
SCFD1	3593
PPP6R3	3323
TMED3	2779
CTSC	2547
CSNK1D	2412
MGAT2	1670
NAPA	1385
SEC31A	1144
CNIH2	727
B4GALT4	587
SEC16B	351
TMED10	328
COG4	15
TBC1D20	-49
GOSR1	-160
COG8	-406
SEC23IP	-469
BET1	-631
MANEA	-658
MAN2A1	-1350
GOSR2	-1504
ARFGAP1	-1962
MAN1A2	-2017
MGAT4C	-2101
KDELR3	-2154
MGAT3	-2157
TRAPPC2L	-2337
SEC24C	-2615
NAPB	-2763
MGAT5	-3137
COG5	-3318
SPTBN5	-3449
DYNLL2	-4042
DCTN5	-4140
SEC22C	-4285
GBF1	-4322
ANK3	-4974
SEC22A	-5080
SPTBN2	-5189
COG3	-5230
GOLGB1	-5425
MGAT4A	-5545
ARFGAP2	-5850
COG6	-5872
B4GALT2	-6126
ANKRD28	-6311
MIA3	-6330
MAN1C1	-6459
TRAPPC4	-6836
BET1L	-7385
SPTBN1	-7419
DYNC1H1	-7822
COG2	-8023
TRAPPC2	-8851
B4GALT6	-8981
CNIH3	-9196
TRAPPC10	-9516
FUT8	-9752
B4GALT3	-10619
LMAN1	-10699
TRAPPC6A	-10921
STX17	-11009
COPZ2	-11047
SPTAN1	-11438
ST8SIA6	-11578
CHST10	-11858
ST6GAL1	-11887
COG1	-12057

---

RHO GTPase Effectors

	885
set	RHO GTPase Effectors
setSize	250
pANOVA	2.84e-11
s.dist	0.244
p.adjustANOVA	9.69e-10

Top enriched genes

GeneID	Gene Rank
WASF1	9568
S100A9	9562
S100A8	9560
H2AJ	9418
H2BC21	9368
NCF4	9365
GRB2	9320
YWHAG	9310
ARPC1B	9303
CYFIP1	9270
CTNNA1	9237
MAPK14	9219
NCF2	9209
H2BC12	9178
MAPK3	9078
DLG4	9070
ACTB	9060
PRKCD	9012
YWHAE	9009
CYBB	9000

Click HERE to show all gene set members

GeneID	Gene Rank
WASF1	9568.0
S100A9	9562.0
S100A8	9560.0
H2AJ	9418.0
H2BC21	9368.0
NCF4	9365.0
GRB2	9320.0
YWHAG	9310.0
ARPC1B	9303.0
CYFIP1	9270.0
CTNNA1	9237.0
MAPK14	9219.0
NCF2	9209.0
H2BC12	9178.0
MAPK3	9078.0
DLG4	9070.0
ACTB	9060.0
PRKCD	9012.0
YWHAE	9009.0
CYBB	9000.0
ARPC1A	8923.0
H3-3A	8754.0
RAC1	8720.0
MYL6	8687.0
ACTG1	8671.0
ARPC5	8653.0
YWHAH	8621.0
WAS	8596.0
RHOG	8544.0
CLIP1	8474.0
MRTFA	8376.0
WASF2	8373.0
DIAPH2	8365.0
TAX1BP3	8343.0
ARPC3	8309.0
PPP2CA	8308.0
B9D2	8262.0
PAK1	8252.0
CFL1	8242.0
PAK2	8226.0
RHOA	8218.0
LIMK2	8190.0
IQGAP1	8189.0
H2BC5	8163.0
KIF5B	8144.0
H2BC11	8076.0
H2AC6	8070.0
ACTR3	7888.0
ACTR2	7827.0
PPP2CB	7769.0
NDEL1	7753.0
MYL9	7719.0
MAPRE1	7700.0
DYNC1I2	7629.0
ARPC4	7605.0
NCKAP1	7562.0
H2BC4	7549.0
CDC42	7539.0
MAPK1	7520.0
NCKAP1L	7516.0
RHOQ	7504.0
H2BC17	7502.0
KLC3	7479.0
ARPC2	7449.0
ROCK1	7445.0
NCF1	7433.0
SRF	7205.0
BTK	7156.0
ABI1	7154.0
PPP1CB	7093.0
BRK1	7085.0
PRKCB	7056.0
PPP1R14A	7009.0
DYNC1LI1	6992.0
CYBA	6952.0
WASF3	6915.0
PPP2R5B	6870.0
H3C15	6780.5
MYH9	6772.0
MYLK	6690.0
CTNNB1	6463.0
YWHAB	6398.0
PPP1CC	6334.0
IQGAP2	6286.0
PDPK1	6209.0
ROCK2	6151.0
PPP1R12A	6131.0
H2AZ1	6126.0
DYNLL1	6049.0
CTTN	5999.0
PPP2R5A	5985.0
SRGAP2	5824.0
SEC13	5820.0
WIPF2	5769.0
DVL3	5734.0
YWHAZ	5687.0
KLC1	5596.0
PFN1	5562.0
PAFAH1B1	5534.0
TAOK1	5471.0
H2BC9	5461.0
H2BC15	5458.0
NSL1	5429.0
RAC2	5238.0
MYL12B	5177.0
H2AC20	5039.0
CDC25C	5024.0
AR	4913.0
LIMK1	4741.0
PPP2R1A	4669.0
PTK2	4506.0
DIAPH3	4446.0
CENPA	4259.0
DYNC1LI2	4253.0
DYNC1I1	4211.0
FMNL1	4191.0
CDC20	4087.0
BIRC5	4082.0
MAPK11	3955.0
DAAM1	3591.0
IQGAP3	3509.0
BUB1	3411.0
PMF1	3407.0
KIF14	3370.0
KTN1	3322.0
NUP37	3153.0
NUP98	3124.0
BUB1B	3104.0
KLK2	3082.0
PLK1	3065.0
CENPF	2876.0
SKA1	2798.0
CFTR	2738.0
NDE1	2635.0
PPP2R5D	2440.0
SPC24	2393.0
PPP1R12B	1737.0
PIK3C3	1626.0
SFN	1557.0
RHOB	1190.0
PRKCA	1163.0
PRC1	1119.0
NCOA2	1109.0
AURKB	959.0
KIF2C	812.0
CENPE	741.0
MYH10	663.0
WIPF1	581.0
FLNA	547.0
NCKIPSD	320.0
WASL	283.0
ABL1	229.0
PKN2	151.0
DVL1	61.0
ZW10	37.0
CENPN	24.0
ITGB1	-50.0
BAIAP2	-179.0
PPP2R1B	-246.0
KNL1	-360.0
ERCC6L	-418.0
CLASP1	-573.0
PPP2R5E	-627.0
NUDC	-674.0
DIAPH1	-704.0
RANBP2	-808.0
KIF2A	-1080.0
XPO1	-1199.0
H2AZ2	-1266.0
AHCTF1	-1621.0
CDCA8	-1850.0
PKN1	-1986.0
CALM1	-2048.0
CLASP2	-2169.0
PFN2	-2375.0
KIF18A	-2744.0
NUP85	-3077.0
CENPI	-3165.0
PIN1	-3272.0
SGO2	-3359.0
MYH11	-3490.0
PKN3	-3714.0
FMNL2	-3776.0
LIN7B	-3872.0
PIK3R4	-4040.0
DYNLL2	-4042.0
PAK3	-4194.0
NUF2	-4325.0
RHPN2	-4434.0
ZWINT	-4758.0
RHPN1	-4792.0
CIT	-5008.0
MAD1L1	-5035.0
RCC2	-5199.0
CENPO	-5215.0
CENPM	-5373.0
NOXA1	-5532.0
SEH1L	-5957.0
INCENP	-6043.0
CKAP5	-6299.0
CENPQ	-6451.0
CENPU	-6495.0
H2BU1	-6519.0
NF2	-6614.0
SGO1	-6826.0
YWHAQ	-7471.0
ITGB3BP	-7623.0
SCAI	-7817.0
DYNC1H1	-7822.0
NUP133	-7839.0
KNTC1	-7922.0
MAD2L1	-8081.0
KLC4	-8231.0
MEN1	-8265.0
CDKN1B	-8305.0
KIF5A	-8378.0
CENPK	-8469.0
KLC2	-8724.0
CENPH	-8745.0
SKA2	-8943.0
SRC	-9011.0
NDC80	-9117.0
CENPT	-9416.0
KDM1A	-9476.0
NUP43	-9595.0
RPS27	-9651.0
GOPC	-9696.0
NUP160	-10383.0
CYFIP2	-10387.0
MIS12	-10502.0
KDM4C	-10513.0
NUP107	-10570.0
DVL2	-10753.0
ABI2	-10893.0
DSN1	-10945.0
SPDL1	-11264.0
RHOC	-11333.0
PPP2R5C	-11413.0
NCK1	-11488.0
PRKCZ	-11508.0
CDH1	-11512.0
BUB3	-11546.0
RANGAP1	-11665.0
ZWILCH	-11800.0
CENPL	-11807.0
CENPP	-11863.0
FMNL3	-11869.0
CENPC	-11902.0
EVL	-12046.0
RTKN	-12215.0

---

MyD88 dependent cascade initiated on endosome

	687
set	MyD88 dependent cascade initiated on endosome
setSize	89
pANOVA	5.33e-11
s.dist	0.402
p.adjustANOVA	1.73e-09

Top enriched genes

GeneID	Gene Rank
S100A12	9567
TLR8	9335
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
APP	9123
MAPK3	9078
MAP2K6	9010
TLR4	8981
MAP2K1	8960
LY96	8871
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959

Click HERE to show all gene set members

GeneID	Gene Rank
S100A12	9567
TLR8	9335
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
APP	9123
MAPK3	9078
MAP2K6	9010
TLR4	8981
MAP2K1	8960
LY96	8871
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959
RPS6KA1	7800
PPP2CB	7769
PELI3	7736
MAPK1	7520
TAB2	7070
MAP2K4	6948
NFKBIA	6835
UBB	6737
PELI1	6596
TICAM1	6380
NFKB1	6367
FBXW11	6282
MAP3K8	6262
TICAM2	6244
FOS	6179
IRAK1	6159
ATF1	5790
TAB1	5711
UBE2V1	5681
TNIP2	5630
IKBKG	5434
MAP3K1	5160
ECSIT	4997
PPP2R1A	4669
UBC	4421
DUSP6	4367
SKP1	4349
MAPKAPK2	4176
MAPK10	4136
JUN	3964
MAPK11	3955
RPS6KA2	3177
TAB3	3165
RPS6KA3	3012
MAP3K7	2453
PPP2R5D	2440
ATF2	2110
UBE2N	1951
MAP2K7	1647
AGER	1309
VRK3	1293
UBA52	1071
RIPK2	1042
ELK1	1040
NKIRAS1	387
NFKBIB	-88
HMGB1	-200
TRAF6	-241
PPP2R1B	-246
MEF2C	-319
TLR7	-655
NFKB2	-865
MAPK7	-1294
CREB1	-1382
RELA	-1807
DUSP7	-3253
BTRC	-4932
S100B	-5025
IKBKB	-5290
TLR9	-5909
DUSP4	-6432
RPS27A	-6894
MAPK9	-7182
IRF7	-8889
MAPK8	-9646
IRAK2	-9718
CUL1	-11467
RPS6KA5	-11616
NOD1	-12234

---

Toll Like Receptor 7/8 (TLR7/8) Cascade

	1241
set	Toll Like Receptor 7/8 (TLR7/8) Cascade
setSize	89
pANOVA	5.33e-11
s.dist	0.402
p.adjustANOVA	1.73e-09

Top enriched genes

GeneID	Gene Rank
S100A12	9567
TLR8	9335
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
APP	9123
MAPK3	9078
MAP2K6	9010
TLR4	8981
MAP2K1	8960
LY96	8871
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959

Click HERE to show all gene set members

GeneID	Gene Rank
S100A12	9567
TLR8	9335
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
APP	9123
MAPK3	9078
MAP2K6	9010
TLR4	8981
MAP2K1	8960
LY96	8871
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959
RPS6KA1	7800
PPP2CB	7769
PELI3	7736
MAPK1	7520
TAB2	7070
MAP2K4	6948
NFKBIA	6835
UBB	6737
PELI1	6596
TICAM1	6380
NFKB1	6367
FBXW11	6282
MAP3K8	6262
TICAM2	6244
FOS	6179
IRAK1	6159
ATF1	5790
TAB1	5711
UBE2V1	5681
TNIP2	5630
IKBKG	5434
MAP3K1	5160
ECSIT	4997
PPP2R1A	4669
UBC	4421
DUSP6	4367
SKP1	4349
MAPKAPK2	4176
MAPK10	4136
JUN	3964
MAPK11	3955
RPS6KA2	3177
TAB3	3165
RPS6KA3	3012
MAP3K7	2453
PPP2R5D	2440
ATF2	2110
UBE2N	1951
MAP2K7	1647
AGER	1309
VRK3	1293
UBA52	1071
RIPK2	1042
ELK1	1040
NKIRAS1	387
NFKBIB	-88
HMGB1	-200
TRAF6	-241
PPP2R1B	-246
MEF2C	-319
TLR7	-655
NFKB2	-865
MAPK7	-1294
CREB1	-1382
RELA	-1807
DUSP7	-3253
BTRC	-4932
S100B	-5025
IKBKB	-5290
TLR9	-5909
DUSP4	-6432
RPS27A	-6894
MAPK9	-7182
IRF7	-8889
MAPK8	-9646
IRAK2	-9718
CUL1	-11467
RPS6KA5	-11616
NOD1	-12234

---

Toll Like Receptor 9 (TLR9) Cascade

	1242
set	Toll Like Receptor 9 (TLR9) Cascade
setSize	93
pANOVA	9.72e-11
s.dist	0.388
p.adjustANOVA	3.08e-09

Top enriched genes

GeneID	Gene Rank
S100A12	9567
TLR8	9335
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
APP	9123
MAPK3	9078
MAP2K6	9010
TLR4	8981
MAP2K1	8960
LY96	8871
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959

Click HERE to show all gene set members

GeneID	Gene Rank
S100A12	9567
TLR8	9335
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
APP	9123
MAPK3	9078
MAP2K6	9010
TLR4	8981
MAP2K1	8960
LY96	8871
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959
RPS6KA1	7800
PPP2CB	7769
PELI3	7736
MAPK1	7520
TAB2	7070
MAP2K4	6948
NFKBIA	6835
UBB	6737
PELI1	6596
TICAM1	6380
NFKB1	6367
FBXW11	6282
MAP3K8	6262
TICAM2	6244
FOS	6179
IRAK1	6159
ATF1	5790
TAB1	5711
UBE2V1	5681
TNIP2	5630
IKBKG	5434
MAP3K1	5160
ECSIT	4997
PPP2R1A	4669
EEA1	4631
UBC	4421
DUSP6	4367
SKP1	4349
MAPKAPK2	4176
MAPK10	4136
JUN	3964
MAPK11	3955
RPS6KA2	3177
TAB3	3165
RPS6KA3	3012
MAP3K7	2453
PPP2R5D	2440
ATF2	2110
UBE2N	1951
MAP2K7	1647
PIK3C3	1626
AGER	1309
VRK3	1293
UBA52	1071
RIPK2	1042
ELK1	1040
NKIRAS1	387
NFKBIB	-88
HMGB1	-200
TRAF6	-241
PPP2R1B	-246
MEF2C	-319
TLR7	-655
NFKB2	-865
MAPK7	-1294
CREB1	-1382
RELA	-1807
DUSP7	-3253
PIK3R4	-4040
RBSN	-4574
BTRC	-4932
S100B	-5025
IKBKB	-5290
TLR9	-5909
DUSP4	-6432
RPS27A	-6894
MAPK9	-7182
IRF7	-8889
MAPK8	-9646
IRAK2	-9718
CUL1	-11467
RPS6KA5	-11616
NOD1	-12234

---

Signaling by NTRK1 (TRKA)

	1117
set	Signaling by NTRK1 (TRKA)
setSize	101
pANOVA	1.65e-10
s.dist	0.368
p.adjustANOVA	5.11e-09

Top enriched genes

GeneID	Gene Rank
DUSP3	9324
GRB2	9320
MAPK14	9219
RIT1	9174
MAPK3	9078
PIK3CB	9065
CLTC	9056
MAP2K1	8960
CRK	8941
FOSL1	8911
AP2M1	8673
CDK5	8663
RALB	8475
CLTA	8402
IRS2	8323
LYL1	8321
PPP2CA	8308
MAPKAPK3	8255
RHOA	8218
STAT3	8152

Click HERE to show all gene set members

GeneID	Gene Rank
DUSP3	9324
GRB2	9320
MAPK14	9219
RIT1	9174
MAPK3	9078
PIK3CB	9065
CLTC	9056
MAP2K1	8960
CRK	8941
FOSL1	8911
AP2M1	8673
CDK5	8663
RALB	8475
CLTA	8402
IRS2	8323
LYL1	8321
PPP2CA	8308
MAPKAPK3	8255
RHOA	8218
STAT3	8152
AP2S1	8080
MEF2A	8030
RPS6KA1	7800
PPP2CB	7769
TRIB1	7725
MAPK1	7520
AP2A2	7360
RAP1A	7319
SRF	7205
DNM3	7167
KIDINS220	7111
MAP2K2	6906
JUNB	6889
AP2A1	6628
YWHAB	6398
EP300	6208
FOS	6179
DNM2	6163
ATF1	5790
NRAS	5411
PIK3R2	5051
ID1	4819
PIK3CA	4697
PPP2R1A	4669
SGK1	4642
SHC2	4499
DUSP6	4367
MAPKAPK2	4176
SHC1	4173
SHC3	4054
CRKL	3986
MAP2K5	3957
MAPK11	3955
KRAS	3760
MAPK13	3704
DNM1	3526
DNAL4	3391
ADORA2A	3227
RPS6KA2	3177
RPS6KA3	3012
EGR1	2965
RALA	2686
PPP2R5D	2440
ATF2	2110
IRS1	1806
JUND	1561
FOSB	1432
NAB1	1315
BRAF	1314
VRK3	1293
TF	1172
ELK1	1040
REST	945
PPP2R1B	-246
MEF2C	-319
EGR3	-690
MAPK12	-946
CDK5R1	-1166
TCF12	-1268
MAPK7	-1294
CREB1	-1382
EGR2	-2130
AP2B1	-2748
MEF2D	-3132
DUSP7	-3253
HRAS	-3335
FRS2	-3430
CHD4	-4576
SOS1	-5714
DUSP4	-6432
NTRK1	-7791
ID3	-8629
TPH1	-8787
SRC	-9011
PIK3R1	-9725
RAPGEF1	-10033
NAB2	-10348
PLCG1	-10473
ID2	-11019
RPS6KA5	-11616
RALGDS	-12117

---

Translocation of ZAP-70 to Immunological synapse

	1278
set	Translocation of ZAP-70 to Immunological synapse
setSize	24
pANOVA	2.76e-10
s.dist	-0.744
p.adjustANOVA	8.37e-09

Top enriched genes

GeneID	Gene Rank
CD247	-12295
HLA-DPA1	-12271
HLA-DPB1	-12203
HLA-DRA	-12007
TRBC1	-11859
ZAP70	-11833
HLA-DQA1	-11763
LCK	-11492
CD3G	-11409
CD3D	-11094
CD3E	-11042
TRAC	-10981
TRBV12-3	-10279
TRAV19	-10023
TRBV7-9	-9564
HLA-DQB2	-9390
TRAV8-4	-9384
TRAV29DV5	-9334
HLA-DRB1	-8159
HLA-DQB1	-5703

Click HERE to show all gene set members

GeneID	Gene Rank
CD247	-12295
HLA-DPA1	-12271
HLA-DPB1	-12203
HLA-DRA	-12007
TRBC1	-11859
ZAP70	-11833
HLA-DQA1	-11763
LCK	-11492
CD3G	-11409
CD3D	-11094
CD3E	-11042
TRAC	-10981
TRBV12-3	-10279
TRAV19	-10023
TRBV7-9	-9564
HLA-DQB2	-9390
TRAV8-4	-9384
TRAV29DV5	-9334
HLA-DRB1	-8159
HLA-DQB1	-5703
CD4	-5320
HLA-DRB5	-5140
HLA-DQA2	-4793
PTPN22	-1112

---

Gene expression (Transcription)

	444
set	Gene expression (Transcription)
setSize	1335
pANOVA	3.26e-10
s.dist	-0.102
p.adjustANOVA	9.66e-09

Top enriched genes

GeneID	Gene Rank
FASLG	-12319
TFDP2	-12315
RUNX3	-12312
ERBB2	-12281
SUV39H1	-12270
NFATC2	-12236
DNMT1	-12192
YES1	-12143
GATA3	-12140
MYBL1	-12136
PTPN4	-12133
RAD1	-12131
ZNF599	-12123
NDC1	-12113
AUTS2	-12091
RBBP7	-12085
ZNF3	-12084
ZNF287	-12042
PRKCQ	-12039
PHF19	-12031

Click HERE to show all gene set members

GeneID	Gene Rank
FASLG	-12319.0
TFDP2	-12315.0
RUNX3	-12312.0
ERBB2	-12281.0
SUV39H1	-12270.0
NFATC2	-12236.0
DNMT1	-12192.0
YES1	-12143.0
GATA3	-12140.0
MYBL1	-12136.0
PTPN4	-12133.0
RAD1	-12131.0
ZNF599	-12123.0
NDC1	-12113.0
AUTS2	-12091.0
RBBP7	-12085.0
ZNF3	-12084.0
ZNF287	-12042.0
PRKCQ	-12039.0
PHF19	-12031.0
MDC1	-11988.0
MOV10	-11980.0
RPA1	-11962.0
WRN	-11954.0
FANCI	-11952.0
PRR5	-11948.0
TP53RK	-11910.0
SMAD7	-11905.0
ZNF74	-11899.0
ZNF461	-11892.0
ZNF530	-11884.0
NUAK1	-11875.0
RORA	-11872.0
ANAPC1	-11870.0
DLL1	-11843.0
ZNF250	-11834.0
ZNF43	-11824.0
DGCR8	-11822.0
AKT3	-11804.0
ZNF70	-11798.0
ZNF620	-11789.0
STAT1	-11769.0
ZNF682	-11765.0
RFC5	-11754.0
ZNF33B	-11744.0
TNRC6C	-11737.0
CAMK2D	-11728.0
BRIP1	-11720.0
ZNF554	-11703.0
NUP93	-11700.0
GLS	-11674.0
ZNF571	-11667.0
ZNF724	-11663.0
CCNE1	-11655.0
CCND2	-11649.0
ZNF500	-11640.0
POLR1E	-11638.0
SMARCD1	-11632.0
ZNF696	-11623.0
ZNF286A	-11614.0
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PCGF6	-708.0
RRAGB	-689.0
CDC27	-659.0
SKIL	-606.0
ZNF558	-592.0
NPPA	-569.0
MBD3	-546.0
PSMA4	-538.0
PABPN1	-526.0
ZNF716	-511.0
MAML2	-476.0
MEF2C	-319.0
TTF1	-255.0
PPP2R1B	-246.0
MED14	-205.0
RRM2	-188.0
ZNF587	-183.0
ZNF200	-170.0
HUS1	-131.0
ZNF222	-72.0
BRD7	-36.0
ZNF347	-33.0
KLF4	11.0
MT-CO2	35.0
MT-CO3	47.0
ARID4B	56.0
ELL3	65.0
KMT2C	71.0
LEO1	84.0
WDR61	87.0
APOE	103.0
WDR5	123.0
UHRF1	177.0
MED7	178.0
COX16	214.0
ABL1	229.0
TRIAP1	238.0
TCF7L1	265.0
INTS12	267.0
MLST8	304.0
POLR2I	316.0
CSTF3	334.0
AKT2	345.0
ZNF100	353.0
ZNF776	366.0
NELFB	385.0
HDAC1	394.0
PPP1R13L	418.0
CCNB1	460.0
PLAGL1	465.0
CSF1R	487.0
YY1	529.0
MYB	555.0
COX7C	558.0
CCNA1	575.0
TEAD2	599.0
NR3C1	600.0
SNRPE	610.0
BANP	649.0
SNAPC1	655.0
MT-CO1	675.0
CLDN5	702.0
COX6C	721.0
SETD1B	751.0
KAT6A	764.0
INTS1	766.0
NUP62	772.0
CCNH	783.0
NFIB	815.0
PPARA	865.0
U2AF1	882.0
THOC2	906.0
AURKB	959.0
MAGOH	995.0
RBBP5	1009.0
ZNF429	1060.0
UBA52	1071.0
RPRD1B	1159.0
KMT2B	1204.0
GCK	1242.0
TAF9	1249.0
PRKAB1	1302.0
ZNF394	1327.0
HDAC9	1347.0
HSP90AA1	1348.0
PRKAA1	1352.0
KAT5	1361.0
AFF4	1390.0
ITCH	1394.0
ZKSCAN5	1418.0
CDK1	1480.0
MED31	1486.0
POLR2C	1531.0
SFN	1557.0
THRB	1600.0
POU2F1	1611.0
SNRPD3	1613.0
ATXN3	1623.0
SNRPG	1630.0
PSMD10	1646.0
ELF1	1662.0
CCNA2	1676.0
KCTD15	1753.0
TNFRSF10A	1785.0
TPX2	1833.0
CAV1	1856.0
CCNC	1883.0
CAMK2G	1888.0
ZNF658B	1910.0
NR1I3	1915.0
ZNF613	1941.0
PRKAG2	1942.0
TAF7	1986.0
PSMC3	2018.0
MED12	2042.0
PVALB	2049.0
CNOT11	2103.0
ATF2	2110.0
CBFB	2152.0
OPRM1	2186.0
ZKSCAN1	2205.0
CBX4	2237.0
STK11	2241.0
NBN	2243.0
CHM	2291.0
HDAC10	2302.0
GTF2E1	2363.0
MYC	2367.0
SRSF1	2377.0
MYBL2	2543.0
PSMB4	2552.0
SARNP	2564.0
MED13	2566.0
ELF2	2628.0
DEK	2655.0
PSMC2	2696.0
ZNF586	2702.0
PSMD14	2703.0
GTF2A1	2744.0
SLU7	2754.0
NRBP1	2851.0
SLC38A9	2861.0
BTG2	2864.0
E2F8	2873.0
RNU1-1	2891.5
ZNF471	2905.0
CCNK	2936.0
VENTX	2938.0
POMC	2971.0
SUPT4H1	3005.0
MED17	3008.0
CDC26	3013.0
ZNF770	3021.0
RNGTT	3030.0
GTF2H2	3035.0
AGO2	3046.0
RAD9B	3101.0
NUP98	3124.0
GATAD2A	3125.0
DDX21	3131.0
HDAC8	3141.0
NUP37	3153.0
THOC6	3226.0
KMT2D	3244.0
MED4	3271.0
HTT	3299.0
MYO1C	3351.0
CTR9	3381.0
ZNF445	3386.0
CPSF7	3398.0
PSMB1	3422.0
CREBBP	3460.0
PRDX2	3467.0
AURKA	3503.0
NFYA	3506.0
PSMD5	3507.0
PAF1	3523.0
ERCC2	3545.0
ZNF189	3549.0
RNF2	3573.0
PRMT5	3578.0
POLR2G	3581.0
SURF1	3585.0
ZNF205	3595.0
GTF2B	3599.0
RTF1	3600.0
SESN2	3606.0
SSU72	3617.0
U2AF2	3622.0
TAF8	3643.0
AKT1	3656.0
FAS	3710.0
ZNF668	3732.0
KRAS	3760.0
ZNF667	3775.0
SRSF4	3801.0
DPY30	3810.0
TMEM219	3875.0
GTF2H5	3879.0
PIWIL4	3883.0
ZNF354A	3918.0
NELFE	3922.0
PPARGC1A	3934.0
MAPK11	3955.0
JUN	3964.0
ZNF747	3974.0
CSNK2B	3987.0
ZNF333	4038.0
RBX1	4039.0
BIRC5	4082.0
CASP1	4086.0
CBX6	4091.0
PSMB2	4103.0
MDM2	4179.0
POU2F2	4246.0
COX4I1	4252.0
MAX	4285.0
TSNAX	4305.0
INTS10	4333.0
DNMT3B	4348.0
SKP1	4349.0
ING2	4405.0
UBC	4421.0
KCTD6	4434.0
SEM1	4436.0
CDKN1A	4438.0
MED26	4456.0
SOD2	4458.0
TACO1	4468.0
LAMTOR4	4487.0
NUP50	4544.0
COX7B	4554.0
CTSL	4583.0
SUDS3	4587.0
TBL1XR1	4627.0
RPRD1A	4632.0
SGK1	4642.0
POLR2F	4646.0
IPO8	4660.0
PPP2R1A	4669.0
NDRG1	4678.0
PSMD3	4693.0
ZNF552	4708.0
NOTCH1	4733.0
HDAC3	4734.0
ZNF774	4747.0
HDAC5	4761.0
SMARCA4	4789.0
HDAC11	4790.0
CNOT6	4799.0
UBE2S	4810.0
ZNF20	4817.0
DLX6	4879.0
CBX3	4882.0
ARID1A	4896.0
AR	4913.0
CRCP	4914.0
DDIT3	4938.0
SMAD2	4939.0
CCNG1	4943.0
ZNF282	5019.0
CDC25C	5024.0
RRAGC	5033.0
H2AC20	5039.0
RFC2	5040.0
GTF2F1	5042.0
ELL	5057.0
SNAPC2	5072.0
CTSK	5077.0
CDC73	5093.0
SAP18	5096.0
NR2F6	5106.0
ZNF775	5121.0
MAPKAP1	5130.0
RAE1	5152.0
COX6A1	5167.0
UBE2C	5168.0
CCNE2	5178.0
TGFB1	5201.0
GPRIN1	5211.0
SNW1	5255.0
SAP30L	5271.0
NOTCH2	5276.0
CASC3	5289.0
NFIX	5290.0
CDK7	5292.0
CRADD	5317.0
MED16	5319.0
POLR2L	5362.0
CNOT3	5371.0
PTPN11	5383.0
TWIST2	5405.0
SLBP	5410.0
PSMA2	5433.0
MAML1	5447.0
H2BC15	5458.0
H2BC9	5461.0
ALYREF	5493.0
GTF2F2	5503.0
CBX8	5523.0
USP9X	5542.0
HDAC2	5569.0
PRKAG1	5582.0
RYBP	5586.0
TP53BP2	5594.0
EAF1	5607.0
PBRM1	5635.0
AGO1	5660.0
G6PC	5665.0
YWHAZ	5687.0
INTS6	5751.0
COX6B1	5755.0
PF4	5777.0
PTPN1	5797.0
SEC13	5820.0
RNF111	5821.0
KDM5B	5826.0
PSMD8	5845.0
GTF2E2	5856.0
PRELID1	5864.0
HIPK1	5901.0
ZNF385A	5929.0
IWS1	5941.0
THBS1	5946.0
ESRRA	5973.0
PSMA6	5978.0
NCOR1	5979.0
ASH2L	5989.0
PSMD13	5991.0
BAX	5996.0
PSMD7	6017.0
ZNF213	6031.0
HDAC7	6070.0
BID	6075.0
STEAP3	6076.0
H2AZ1	6126.0
IRAK1	6159.0
FOS	6179.0
CSNK2A1	6207.0
EP300	6208.0
PDPK1	6209.0
HIPK2	6215.0
COX5A	6238.0
GPI	6246.0
ANAPC11	6249.0
BRCA1	6273.0
MED25	6290.0
CTDP1	6295.0
PSMD11	6296.0
TIGAR	6306.0
INTS3	6311.0
GP1BA	6320.0
COX5B	6328.0
RRAGA	6344.0
RARA	6365.0
NFKB1	6367.0
MBD2	6373.0
THOC7	6391.0
E2F4	6395.0
YWHAB	6398.0
USP7	6410.0
CSNK2A2	6430.0
LSM10	6432.0
CTNNB1	6463.0
CITED2	6467.0
E2F1	6473.0
FOXO4	6493.0
PSMD12	6537.0
CPSF3	6549.0
TP53INP1	6554.0
NDUFA4	6586.0
SATB2	6611.0
SREBF1	6642.0
TAL1	6644.0
POLR1D	6651.0
CLP1	6691.0
PSMC6	6701.0
COX8A	6712.0
GSK3B	6720.0
PSMF1	6724.0
EAF2	6729.0
UBB	6737.0
CCNG2	6752.0
PLK3	6767.0
POLR2J	6769.0
H3C15	6780.5
TDG	6789.0
ZNF230	6798.0
CDC40	6836.0
RRM2B	6849.0
MED20	6851.0
UBE2E1	6853.0
JUNB	6889.0
GTF3C6	6904.0
PSMB6	6927.0
ZNF710	6928.0
SUMO1	6973.0
SMARCD2	6976.0
RMI1	6994.0
PRKCB	7056.0
PSMC1	7096.0
PRDX1	7104.0
PSMA7	7174.0
TAF10	7190.0
GTF2A2	7207.0
ZNF267	7214.0
PAPOLA	7250.0
PSMB3	7265.0
PSMD1	7283.0
BCL2L11	7326.0
TAF13	7332.0
JARID2	7334.0
THOC5	7343.0
PSMA1	7346.0
ELOA	7366.0
ZNF143	7367.0
EIF4A3	7369.0
POLDIP3	7378.0
VEGFA	7389.0
PSMD2	7470.0
ZFHX3	7472.0
H2BC17	7502.0
CCND3	7510.0
NR1H2	7512.0
RXRA	7513.0
MAPK1	7520.0
SRSF9	7532.0
H2BC4	7549.0
SERPINE1	7580.0
ELOB	7586.0
RUNX1	7591.0
CITED4	7593.0
MED8	7625.0
ELOC	7637.0
POLR2E	7660.0
RHEB	7675.0
ZNF746	7689.0
LAMTOR3	7692.0
ITGA5	7699.0
LAMTOR2	7704.0
PSMD9	7712.0
MYL9	7719.0
NFYC	7726.0
PPP2CB	7769.0
COX7A2L	7808.0
SMAD6	7853.0
PPM1D	7879.0
PSMD6	7881.0
CPSF2	7886.0
MLLT1	7898.0
ELL2	7901.0
TOP3A	7914.0
TET3	7942.0
NCOR2	7948.0
NEDD4L	7972.0
TNFRSF10C	7974.0
TBL1X	7984.0
NOTCH3	8004.0
NUP214	8011.0
H2AC6	8070.0
H2BC11	8076.0
TAF12	8078.0
TET2	8090.0
KMT5A	8105.0
CEBPB	8108.0
NABP1	8109.0
SAP30	8154.0
H2BC5	8163.0
PSMB5	8188.0
INTS8	8193.0
NRBF2	8203.0
NFIA	8204.0
LBR	8224.0
DICER1	8227.0
VDR	8258.0
PPM1A	8296.0
TXNRD1	8303.0
PPP2CA	8308.0
CNOT8	8312.0
SP1	8315.0
PSME3	8331.0
LMO2	8335.0
TXN	8414.0
TNFRSF10B	8435.0
NFIC	8448.0
SMAD1	8465.0
PSMD4	8498.0
TFDP1	8500.0
PTEN	8516.0
GATA1	8529.0
PSMB7	8535.0
LAMTOR5	8611.0
PRDX5	8612.0
ARID3A	8617.0
LGALS3	8619.0
YWHAH	8621.0
SMARCD3	8637.0
RB1	8649.0
NR6A1	8651.0
JAG1	8661.0
CDK5	8663.0
UBE2D3	8710.0
FOXO3	8729.0
RBPJ	8744.0
H3-3A	8754.0
CDKN2B	8797.0
RRAGD	8850.0
NUP58	8872.0
SPI1	8907.0
FKBP5	8936.0
ITGA2B	8942.0
MAML3	8965.0
YWHAE	9009.0
MAP2K6	9010.0
TGFA	9031.0
ANAPC15	9035.0
G6PD	9045.0
TP53I3	9050.0
PINK1	9054.0
HDAC4	9057.0
ACTB	9060.0
APAF1	9072.0
MAPK3	9078.0
ZNF697	9092.0
AGO4	9094.0
PHC2	9103.0
CARM1	9122.0
UBE2D1	9125.0
CAT	9137.0
SLC2A3	9144.0
TNFRSF10D	9167.0
H2BC12	9178.0
MAPK14	9219.0
RETN	9241.0
GSR	9256.0
GADD45A	9260.0
BCL6	9299.0
YWHAG	9310.0
BNIP3L	9327.0
H2BC21	9368.0
NLRC4	9406.0
H2AJ	9418.0
PRKACA	9441.0
LAMTOR1	9450.0
NFE2	9490.0
SOCS3	9526.0
CR1	9545.0
TDRD9	9566.0
PPARG	9571.0

---

RHO GTPases Activate WASPs and WAVEs

	889
set	RHO GTPases Activate WASPs and WAVEs
setSize	35
pANOVA	5.3e-10
s.dist	0.606
p.adjustANOVA	1.54e-08

Top enriched genes

GeneID	Gene Rank
WASF1	9568
GRB2	9320
ARPC1B	9303
CYFIP1	9270
MAPK3	9078
ACTB	9060
ARPC1A	8923
RAC1	8720
ACTG1	8671
ARPC5	8653
WAS	8596
WASF2	8373
ARPC3	8309
ACTR3	7888
ACTR2	7827
ARPC4	7605
NCKAP1	7562
CDC42	7539
MAPK1	7520
NCKAP1L	7516

Click HERE to show all gene set members

GeneID	Gene Rank
WASF1	9568
GRB2	9320
ARPC1B	9303
CYFIP1	9270
MAPK3	9078
ACTB	9060
ARPC1A	8923
RAC1	8720
ACTG1	8671
ARPC5	8653
WAS	8596
WASF2	8373
ARPC3	8309
ACTR3	7888
ACTR2	7827
ARPC4	7605
NCKAP1	7562
CDC42	7539
MAPK1	7520
NCKAP1L	7516
ARPC2	7449
BTK	7156
ABI1	7154
BRK1	7085
WASF3	6915
WIPF2	5769
PTK2	4506
WIPF1	581
NCKIPSD	320
WASL	283
ABL1	229
BAIAP2	-179
CYFIP2	-10387
ABI2	-10893
NCK1	-11488

---

Intra-Golgi and retrograde Golgi-to-ER traffic

	571
set	Intra-Golgi and retrograde Golgi-to-ER traffic
setSize	179
pANOVA	5.47e-10
s.dist	0.269
p.adjustANOVA	1.56e-08

Top enriched genes

GeneID	Gene Rank
PLIN3	9485
PLA2G4A	9234
ARF4	9201
KDELR1	9163
DCTN2	9158
ARF1	9083
RAB1A	9075
STX10	9047
CUX1	8905
GALNT2	8896
NSF	8815
BICD2	8786
TGOLN2	8647
CAPZA2	8521
KIF3C	8451
RAB1B	8407
DCTN4	8385
COPA	8319
KIF1B	8290
RAB6A	8223

Click HERE to show all gene set members

GeneID	Gene Rank
PLIN3	9485
PLA2G4A	9234
ARF4	9201
KDELR1	9163
DCTN2	9158
ARF1	9083
RAB1A	9075
STX10	9047
CUX1	8905
GALNT2	8896
NSF	8815
BICD2	8786
TGOLN2	8647
CAPZA2	8521
KIF3C	8451
RAB1B	8407
DCTN4	8385
COPA	8319
KIF1B	8290
RAB6A	8223
CAPZA1	8165
KIF5B	8144
VAMP3	8121
CAPZB	8057
MAN1A1	7979
ARF5	7975
COPB2	7965
TMED7	7909
STX6	7907
RAB18	7893
KIF1C	7816
ARF3	7798
ACTR10	7652
COPG2	7636
DYNC1I2	7629
KDELR2	7585
VPS54	7564
NAA38	7561
COPG1	7533
KLC3	7479
COPB1	7399
RAB33B	7385
DCTN6	7382
IGF2R	7270
TMED9	7199
STX5	7186
SURF4	7147
ACTR1A	7088
RAB39A	7059
PAFAH1B2	7026
DYNC1LI1	6992
COPE	6979
RIC1	6733
MAN2A2	6669
GALNT1	6518
RAB43	6507
SNAP29	6418
CYTH4	6170
RAB6B	6149
TMED2	6098
DCTN3	6080
DYNLL1	6049
KIF13B	6047
SEC22B	5939
RAB3GAP1	5800
RAB36	5722
ARCN1	5661
KLC1	5596
KIF23	5584
PAFAH1B1	5534
VTI1A	5381
GOLGA5	5333
YKT6	5277
KIF20A	5165
DCTN1	5143
GOLIM4	5122
STX18	4684
AGPAT3	4625
RGP1	4599
RABEPK	4493
USP6NL	4486
RAB3GAP2	4478
PAFAH1B3	4373
COG7	4321
KIF9	4310
DYNC1LI2	4253
DYNC1I1	4211
NAPG	4190
RAB9A	4177
COPZ1	4081
ARFGAP3	3807
KIF3B	3773
STX16	3771
KIF4A	3763
VAMP4	3236
RACGAP1	2921
KIF16B	2817
TMED3	2779
GCC1	2756
KIF27	2576
VPS45	2526
TMF1	2524
GOLGA1	2474
NAPA	1385
KIF6	1162
KIF11	950
USE1	922
KIF2C	812
CENPE	741
CYTH2	456
SYS1	330
TMED10	328
NBAS	195
ZW10	37
COG4	15
KIF18B	-123
VPS53	-130
GOSR1	-160
KIFC1	-166
COG8	-406
TRIP11	-591
SCOC	-894
KIF2A	-1080
MAN2A1	-1350
GOSR2	-1504
KIFC2	-1555
ARFGAP1	-1962
MAN1A2	-2017
KDELR3	-2154
KIF18A	-2744
NAPB	-2763
ARFIP2	-3098
KIF15	-3246
COG5	-3318
VPS52	-3628
RAB41	-3915
DYNLL2	-4042
GOLGA4	-4063
DCTN5	-4140
GBF1	-4322
KIF26A	-4564
ARL1	-5130
COG3	-5230
ARFGAP2	-5850
COG6	-5872
MAN1C1	-6459
RAB9B	-6471
VPS51	-6565
KIF28P	-6736
KIF21B	-6771
BICD1	-7322
BET1L	-7385
ARFRP1	-7488
BNIP1	-7543
GCC2	-7725
DYNC1H1	-7822
KIF20B	-7903
COG2	-8023
KLC4	-8231
KIF5C	-8297
CYTH3	-8377
KIF5A	-8378
M6PR	-8665
KLC2	-8724
KIFAP3	-8777
RAB30	-8959
NAA30	-9664
RINT1	-10172
COPZ2	-11047
RHOBTB3	-11246
NAA35	-11460
KIF19	-11579
KIF26B	-11671
KIF21A	-11830
KIF3A	-11957
PLA2G6	-12020
COG1	-12057
CYTH1	-12174
KIF22	-12286

---

MyD88 cascade initiated on plasma membrane

	685
set	MyD88 cascade initiated on plasma membrane
setSize	82
pANOVA	6.02e-10
s.dist	0.395
p.adjustANOVA	1.61e-08

Top enriched genes

GeneID	Gene Rank
S100A12	9567
DUSP3	9324
NKIRAS2	9308
TLR5	9254
MAPK14	9219
APP	9123
MAPK3	9078
MAP2K6	9010
MAP2K1	8960
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959
RPS6KA1	7800
PPP2CB	7769
PELI3	7736

Click HERE to show all gene set members

GeneID	Gene Rank
S100A12	9567
DUSP3	9324
NKIRAS2	9308
TLR5	9254
MAPK14	9219
APP	9123
MAPK3	9078
MAP2K6	9010
MAP2K1	8960
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959
RPS6KA1	7800
PPP2CB	7769
PELI3	7736
MAPK1	7520
TAB2	7070
MAP2K4	6948
NFKBIA	6835
UBB	6737
PELI1	6596
NFKB1	6367
FBXW11	6282
MAP3K8	6262
FOS	6179
IRAK1	6159
ATF1	5790
TAB1	5711
UBE2V1	5681
TNIP2	5630
IKBKG	5434
MAP3K1	5160
ECSIT	4997
PPP2R1A	4669
UBC	4421
DUSP6	4367
SKP1	4349
MAPKAPK2	4176
MAPK10	4136
JUN	3964
MAPK11	3955
RPS6KA2	3177
TAB3	3165
RPS6KA3	3012
MAP3K7	2453
PPP2R5D	2440
ATF2	2110
UBE2N	1951
MAP2K7	1647
AGER	1309
VRK3	1293
UBA52	1071
RIPK2	1042
ELK1	1040
NKIRAS1	387
NFKBIB	-88
HMGB1	-200
TRAF6	-241
PPP2R1B	-246
MEF2C	-319
NFKB2	-865
MAPK7	-1294
CREB1	-1382
RELA	-1807
TLR10	-2899
DUSP7	-3253
BTRC	-4932
S100B	-5025
IKBKB	-5290
DUSP4	-6432
RPS27A	-6894
MAPK9	-7182
MAPK8	-9646
IRAK2	-9718
CUL1	-11467
RPS6KA5	-11616
NOD1	-12234

---

Toll Like Receptor 10 (TLR10) Cascade

	1236
set	Toll Like Receptor 10 (TLR10) Cascade
setSize	82
pANOVA	6.02e-10
s.dist	0.395
p.adjustANOVA	1.61e-08

Top enriched genes

GeneID	Gene Rank
S100A12	9567
DUSP3	9324
NKIRAS2	9308
TLR5	9254
MAPK14	9219
APP	9123
MAPK3	9078
MAP2K6	9010
MAP2K1	8960
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959
RPS6KA1	7800
PPP2CB	7769
PELI3	7736

Click HERE to show all gene set members

GeneID	Gene Rank
S100A12	9567
DUSP3	9324
NKIRAS2	9308
TLR5	9254
MAPK14	9219
APP	9123
MAPK3	9078
MAP2K6	9010
MAP2K1	8960
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959
RPS6KA1	7800
PPP2CB	7769
PELI3	7736
MAPK1	7520
TAB2	7070
MAP2K4	6948
NFKBIA	6835
UBB	6737
PELI1	6596
NFKB1	6367
FBXW11	6282
MAP3K8	6262
FOS	6179
IRAK1	6159
ATF1	5790
TAB1	5711
UBE2V1	5681
TNIP2	5630
IKBKG	5434
MAP3K1	5160
ECSIT	4997
PPP2R1A	4669
UBC	4421
DUSP6	4367
SKP1	4349
MAPKAPK2	4176
MAPK10	4136
JUN	3964
MAPK11	3955
RPS6KA2	3177
TAB3	3165
RPS6KA3	3012
MAP3K7	2453
PPP2R5D	2440
ATF2	2110
UBE2N	1951
MAP2K7	1647
AGER	1309
VRK3	1293
UBA52	1071
RIPK2	1042
ELK1	1040
NKIRAS1	387
NFKBIB	-88
HMGB1	-200
TRAF6	-241
PPP2R1B	-246
MEF2C	-319
NFKB2	-865
MAPK7	-1294
CREB1	-1382
RELA	-1807
TLR10	-2899
DUSP7	-3253
BTRC	-4932
S100B	-5025
IKBKB	-5290
DUSP4	-6432
RPS27A	-6894
MAPK9	-7182
MAPK8	-9646
IRAK2	-9718
CUL1	-11467
RPS6KA5	-11616
NOD1	-12234

---

Toll Like Receptor 5 (TLR5) Cascade

	1240
set	Toll Like Receptor 5 (TLR5) Cascade
setSize	82
pANOVA	6.02e-10
s.dist	0.395
p.adjustANOVA	1.61e-08

Top enriched genes

GeneID	Gene Rank
S100A12	9567
DUSP3	9324
NKIRAS2	9308
TLR5	9254
MAPK14	9219
APP	9123
MAPK3	9078
MAP2K6	9010
MAP2K1	8960
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959
RPS6KA1	7800
PPP2CB	7769
PELI3	7736

Click HERE to show all gene set members

GeneID	Gene Rank
S100A12	9567
DUSP3	9324
NKIRAS2	9308
TLR5	9254
MAPK14	9219
APP	9123
MAPK3	9078
MAP2K6	9010
MAP2K1	8960
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
PELI2	8166
MYD88	8091
MEF2A	8030
CHUK	7959
RPS6KA1	7800
PPP2CB	7769
PELI3	7736
MAPK1	7520
TAB2	7070
MAP2K4	6948
NFKBIA	6835
UBB	6737
PELI1	6596
NFKB1	6367
FBXW11	6282
MAP3K8	6262
FOS	6179
IRAK1	6159
ATF1	5790
TAB1	5711
UBE2V1	5681
TNIP2	5630
IKBKG	5434
MAP3K1	5160
ECSIT	4997
PPP2R1A	4669
UBC	4421
DUSP6	4367
SKP1	4349
MAPKAPK2	4176
MAPK10	4136
JUN	3964
MAPK11	3955
RPS6KA2	3177
TAB3	3165
RPS6KA3	3012
MAP3K7	2453
PPP2R5D	2440
ATF2	2110
UBE2N	1951
MAP2K7	1647
AGER	1309
VRK3	1293
UBA52	1071
RIPK2	1042
ELK1	1040
NKIRAS1	387
NFKBIB	-88
HMGB1	-200
TRAF6	-241
PPP2R1B	-246
MEF2C	-319
NFKB2	-865
MAPK7	-1294
CREB1	-1382
RELA	-1807
TLR10	-2899
DUSP7	-3253
BTRC	-4932
S100B	-5025
IKBKB	-5290
DUSP4	-6432
RPS27A	-6894
MAPK9	-7182
MAPK8	-9646
IRAK2	-9718
CUL1	-11467
RPS6KA5	-11616
NOD1	-12234

---

Developmental Biology

	281
set	Developmental Biology
setSize	732
pANOVA	8.35e-10
s.dist	0.133
p.adjustANOVA	2.19e-08

Top enriched genes

GeneID	Gene Rank
PPARG	9571
GRB10	9508
CD36	9486
LAMC1	9473
NUMB	9457
PRKACA	9441
ST14	9429
H2AJ	9418
MMP9	9370
H2BC21	9368
SDCBP	9367
DSC2	9359
ARHGEF11	9346
GRB2	9320
ALCAM	9318
ARPC1B	9303
FES	9280
SPTB	9250
CTNNA1	9237
PLXNC1	9221

Click HERE to show all gene set members

GeneID	Gene Rank
PPARG	9571.0
GRB10	9508.0
CD36	9486.0
LAMC1	9473.0
NUMB	9457.0
PRKACA	9441.0
ST14	9429.0
H2AJ	9418.0
MMP9	9370.0
H2BC21	9368.0
SDCBP	9367.0
DSC2	9359.0
ARHGEF11	9346.0
GRB2	9320.0
ALCAM	9318.0
ARPC1B	9303.0
FES	9280.0
SPTB	9250.0
CTNNA1	9237.0
PLXNC1	9221.0
ZNF467	9220.0
MAPK14	9219.0
ITSN1	9186.0
H2BC12	9178.0
FURIN	9162.0
RAP1GAP	9159.0
NCSTN	9139.0
CARM1	9122.0
CSTA	9120.0
ACVR1B	9110.0
MAPK3	9078.0
DLG4	9070.0
PIK3CB	9065.0
ACTB	9060.0
CLTC	9056.0
SEMA4A	9048.0
PLXNB3	9028.0
PDLIM7	9027.0
MAP2K6	9010.0
MAML3	8965.0
MAP2K1	8960.0
ITGA2B	8942.0
CLTCL1	8939.0
MYO10	8933.0
ARPC1A	8923.0
SPI1	8907.0
ANK1	8897.0
CEBPD	8826.0
PCSK6	8824.0
ITGA1	8818.0
CSF3R	8795.0
H3-3A	8754.0
RBPJ	8744.0
FOXO3	8729.0
RAC1	8720.0
ADAM10	8705.0
MYL6	8687.0
AP2M1	8673.0
ACTG1	8671.0
CDK5	8663.0
SIAH2	8657.0
ARPC5	8653.0
NR6A1	8651.0
SMARCD3	8637.0
BNIP2	8636.0
CAPN1	8613.0
EPHB3	8581.0
TLN1	8554.0
UNC5A	8543.0
PSMB7	8535.0
TFDP1	8500.0
PSMD4	8498.0
ABLIM3	8403.0
CLTA	8402.0
CEBPA	8386.0
ITGB3	8367.0
SOS2	8350.0
PSME3	8331.0
IRS2	8323.0
ARPC3	8309.0
ST8SIA4	8264.0
PAK1	8252.0
CFL1	8242.0
IL6R	8229.0
PAK2	8226.0
RHOA	8218.0
HMGCR	8207.0
CAP1	8200.0
LIMK2	8190.0
PSMB5	8188.0
H2BC5	8163.0
STAT3	8152.0
VASP	8136.0
SHTN1	8126.0
CEBPB	8108.0
GAB2	8100.0
DOK1	8092.0
EIF4G1	8081.0
AP2S1	8080.0
H2BC11	8076.0
H2AC6	8070.0
MEF2A	8030.0
EPAS1	8002.0
TBL1X	7984.0
NCOR2	7948.0
DPYSL2	7937.0
MAFB	7926.0
RDX	7919.0
MPZ	7918.0
ACTR3	7888.0
PSMD6	7881.0
PSEN1	7843.0
ACTR2	7827.0
RPS6KA1	7800.0
SPTA1	7785.0
LYN	7728.0
MYL9	7719.0
PSMD9	7712.0
ITGA5	7699.0
CDK19	7697.0
POLR2E	7660.0
ELOC	7637.0
MED8	7625.0
ARPC4	7605.0
CAPNS1	7603.0
RUNX1	7591.0
TYROBP	7587.0
ELOB	7586.0
H2BC4	7549.0
CDC42	7539.0
MAPK1	7520.0
RXRA	7513.0
CCND3	7510.0
H2BC17	7502.0
PSMD2	7470.0
ARPC2	7449.0
CEBPE	7447.0
ROCK1	7445.0
DOCK1	7413.0
ETF1	7409.0
PLXND1	7376.0
EIF4A3	7369.0
HHEX	7368.0
AP2A2	7360.0
PSMA1	7346.0
RGMA	7323.0
RPL26L1	7295.0
PSMD1	7283.0
PSMB3	7265.0
PSMA7	7174.0
DNM3	7167.0
PSMC1	7096.0
PLXNA2	7025.0
PPP3CB	6998.0
ITGA9	6984.0
MYL12A	6981.0
LYPLA2	6947.0
CYP51A1	6941.0
PSMB6	6927.0
MAP2K2	6906.0
PITPNA	6864.0
MED20	6851.0
SREBF2	6802.0
H3C15	6780.5
MYH9	6772.0
POLR2J	6769.0
UBB	6737.0
SRGAP1	6726.0
PSMF1	6724.0
GSK3B	6720.0
PSMC6	6701.0
TAL1	6644.0
SREBF1	6642.0
AP2A1	6628.0
KAZN	6605.0
GSPT1	6567.0
PSMD12	6537.0
KRT80	6502.0
MYO9B	6481.0
E2F1	6473.0
CTNNB1	6463.0
CSNK2A2	6430.0
KRT23	6413.0
NFKB1	6367.0
RARA	6365.0
PSMD11	6296.0
MED25	6290.0
PRKAR2A	6265.0
APH1B	6248.0
LGI2	6242.0
SH3KBP1	6227.0
EFNA4	6218.0
EP300	6208.0
CSNK2A1	6207.0
CLTB	6195.0
DNM2	6163.0
ROCK2	6151.0
ITGAV	6133.0
H2AZ1	6126.0
MED13L	6114.0
MEF2B	6113.0
KRT7	6110.0
PIK3CD	6096.0
LIPN	6083.0
PSMD7	6017.0
PSMD13	5991.0
ASH2L	5989.0
NCOR1	5979.0
PSMA6	5978.0
LAMB1	5948.0
RANBP9	5914.0
PSMD8	5845.0
NCOA6	5838.0
PSENEN	5833.0
SRGAP2	5824.0
SCN1B	5762.0
GAB1	5723.0
PLXNB1	5690.0
PKP2	5677.0
FLI1	5589.0
HDAC2	5569.0
PFN1	5562.0
MSN	5556.0
RPS9	5496.0
H2BC9	5461.0
H2BC15	5458.0
MAML1	5447.0
PSMA2	5433.0
NRAS	5411.0
PABPC1	5403.0
ZSWIM8	5400.0
EPHB4	5397.0
PTPN11	5383.0
POLR2L	5362.0
MED16	5319.0
PAGR1	5296.0
CASC3	5289.0
SCN5A	5263.0
SDC2	5257.0
SNW1	5255.0
TGFB1	5201.0
COL9A3	5186.0
PBX1	5182.0
MYL12B	5177.0
KLF5	5053.0
PIK3R2	5051.0
H2AC20	5039.0
NCK2	5007.0
VAV3	4974.0
SMAD2	4939.0
COL6A3	4861.0
SPAG9	4840.0
SLIT1	4825.0
CNOT6	4799.0
SMARCA4	4789.0
LIMK1	4741.0
HDAC3	4734.0
NOTCH1	4733.0
PIK3CA	4697.0
PSMD3	4693.0
TSC22D1	4649.0
POLR2F	4646.0
TBL1XR1	4627.0
KRT1	4597.0
NCOA1	4563.0
RPL3L	4539.0
PTK2	4506.0
MED18	4492.0
MED26	4456.0
CDKN1A	4438.0
SEM1	4436.0
UBC	4421.0
ABL2	4355.0
PRNP	4282.0
CD24	4272.0
EPHB2	4240.0
APH1A	4198.0
SHC1	4173.0
ITGA2	4159.0
PSMB2	4103.0
SHC3	4054.0
RBX1	4039.0
CSNK2B	3987.0
JUN	3964.0
MAPK11	3955.0
PPARGC1A	3934.0
ZNF638	3865.0
KIF4A	3763.0
KRAS	3760.0
MED22	3738.0
ADGRV1	3733.0
MAPK13	3704.0
KDM6A	3671.0
RRAS	3664.0
FGF2	3660.0
AKT1	3656.0
POLR2G	3581.0
NCOA3	3563.0
DNM1	3526.0
CACNA1D	3525.0
PSMD5	3507.0
CREBBP	3460.0
PIP5K1C	3436.0
PSMB1	3422.0
MED19	3287.0
MED4	3271.0
KMT2D	3244.0
ARHGEF12	3230.0
SCN2A	3214.0
RPS6KA2	3177.0
EFNA1	3122.0
PKP4	3115.0
RPS6KA3	3012.0
MED17	3008.0
UNC5B	2914.0
PSPN	2902.0
PI3	2860.0
LPL	2853.0
PSMD14	2703.0
PSMC2	2696.0
KCNQ3	2692.0
DEK	2655.0
MED13	2566.0
CUL2	2559.0
PSMB4	2552.0
DOK4	2550.0
RELN	2540.0
ONECUT1	2520.0
MYC	2367.0
PTPRC	2253.0
CBFB	2152.0
RASA1	2134.0
RPS27L	2117.0
MED12	2042.0
PSMC3	2018.0
RPS6KA4	2000.0
CCNC	1883.0
NANOG	1867.0
TRIO	1829.0
POU5F1	1743.0
PPL	1733.0
PSMD10	1646.0
KRT8	1534.0
POLR2C	1531.0
MED31	1486.0
SCN2B	1413.0
LIN28A	1409.0
HSP90AA1	1348.0
NAB1	1315.0
COL4A3	1268.0
GCK	1242.0
RHOB	1190.0
PRKCA	1163.0
NCOA2	1109.0
UBA52	1071.0
RBBP5	1009.0
MAGOH	995.0
UPF2	986.0
COL4A2	979.0
NFASC	884.0
KRT10	866.0
PPARA	865.0
TIAM1	701.0
MYH10	663.0
MYB	555.0
YY1	529.0
THRAP3	398.0
MSI1	382.0
NTN3	375.0
CACNB3	359.0
AKT2	345.0
POLR2I	316.0
SLIT3	292.0
WASL	283.0
ABL1	229.0
EPHB6	189.0
MED7	178.0
WDR5	123.0
RPL36AL	91.0
EVPL	89.0
KMT2C	71.0
KLF4	11.0
FAM120B	-24.0
ITGB1	-50.0
RPLP1	-65.0
CXCR4	-125.0
MED14	-205.0
RPS4Y1	-222.0
ITGA10	-226.0
RPS24	-282.0
ROBO1	-284.0
MEF2C	-319.0
CNTN2	-336.0
PRSS8	-388.0
FAU	-402.0
MAML2	-476.0
PSMA4	-538.0
SCN9A	-544.0
CLASP1	-573.0
CRMP1	-609.0
MED11	-713.0
USP33	-811.0
DOK2	-832.0
MED6	-888.0
LAMA1	-906.0
MAPK12	-946.0
PSMC5	-948.0
RPL15	-1017.0
RPLP0	-1054.0
CDK5R1	-1166.0
DSP	-1230.0
RPL8	-1242.0
H2AZ2	-1266.0
TCF12	-1268.0
COL6A1	-1276.0
MAPK7	-1294.0
CREB1	-1382.0
KLK14	-1384.0
MED28	-1397.0
RPS26	-1443.0
RND1	-1467.0
RPL28	-1469.0
PAK4	-1502.0
RPL22L1	-1643.0
RPS13	-1759.0
DPPA4	-1785.0
POLR2K	-1792.0
MEIS1	-1799.0
RELA	-1807.0
RPL9	-1827.0
RBBP4	-1907.0
TRPC6	-1948.0
CDK8	-1997.0
RPL7	-2018.0
EGR2	-2130.0
RPS8	-2138.0
CLASP2	-2169.0
HIF3A	-2292.0
PFN2	-2375.0
KAT2B	-2393.0
SUZ12	-2444.0
POLR2B	-2536.0
SCN3A	-2571.0
PKNOX1	-2688.0
AP2B1	-2748.0
ENAH	-2766.0
SEMA4D	-2767.0
POLR2H	-2817.0
ONECUT3	-2886.0
RPL27	-2934.0
STX1B	-2970.0
NRCAM	-2977.0
SIAH1	-3004.0
RPL39	-3047.0
PSMB8	-3080.0
POLR2A	-3105.0
MEF2D	-3132.0
LGI4	-3278.0
HRAS	-3335.0
RPL23	-3352.0
RPL6	-3382.0
ARHGAP35	-3408.0
FRS2	-3430.0
SPTBN5	-3449.0
RPL13	-3461.0
MYH11	-3490.0
ANGPTL4	-3500.0
PLIN1	-3507.0
RPL4	-3592.0
RPL29	-3604.0
COL4A4	-3622.0
RPS15	-3698.0
RPL7A	-3699.0
KALRN	-3725.0
TCF4	-3878.0
NRP2	-3980.0
RPL37A	-4004.0
PRX	-4029.0
POLR2D	-4058.0
STX1A	-4061.0
VAV2	-4073.0
MED1	-4082.0
RPS21	-4115.0
PCGF2	-4179.0
PAK3	-4194.0
VLDLR	-4336.0
CHL1	-4347.0
KRT18	-4416.0
LEFTY1	-4420.0
CACNA1I	-4452.0
RPL31	-4507.0
RPS2	-4509.0
PTPRA	-4528.0
CHD9	-4532.0
RPS16	-4570.0
ARHGEF7	-4627.0
RPL5	-4631.0
RPS28	-4647.0
KRT73	-4666.0
EBF1	-4678.0
GPC1	-4697.0
RPS3A	-4702.0
CD72	-4714.0
NTN1	-4715.0
RPL22	-4738.0
EPHA1	-4744.0
MAMLD1	-4791.0
RARG	-4816.0
KRT72	-4823.0
SCN8A	-4878.0
RGMB	-4969.0
ANK3	-4974.0
RPS7	-5016.0
CDK2	-5018.0
RPL18	-5054.0
SPTBN2	-5189.0
CNTNAP1	-5208.0
RPL36	-5287.0
PSMA3	-5314.0
FGFR1	-5335.0
RPS6KA6	-5441.0
NODAL	-5448.0
RPL17	-5464.0
RPS5	-5478.0
RPS14	-5485.0
TGS1	-5487.0
PMP22	-5527.0
MED30	-5533.0
JUP	-5541.0
TGM1	-5632.0
MED21	-5663.0
RPS10	-5686.0
RPS15A	-5695.0
SOS1	-5714.0
SRGAP3	-5738.0
SOX10	-5748.0
CACNB4	-5759.0
PSMB10	-5768.0
RPS3	-5833.0
AGAP2	-5861.0
NCBP1	-5866.0
SEMA3A	-5876.0
RPL24	-5882.0
RPL38	-5890.0
MBP	-5937.0
SCN4A	-5941.0
SALL4	-5965.0
RPS4X	-5969.0
RPS12	-5985.0
RPL18A	-6029.0
CDH4	-6078.0
RPL35A	-6080.0
CACNB2	-6089.0
PSME4	-6099.0
RPS6	-6100.0
PSMA5	-6154.0
WWTR1	-6206.0
RPSA	-6219.0
RPS17	-6223.0
L1CAM	-6232.0
RPL19	-6242.0
RPS25	-6246.0
RPL11	-6275.0
RPS23	-6279.0
EFNB2	-6280.0
RPL27A	-6321.0
RPL37	-6401.0
RPL21	-6481.0
DPYSL4	-6504.0
RPL14	-6518.0
H2BU1	-6519.0
RET	-6557.0
RPL10	-6562.0
RPL32	-6577.0
DSC1	-6597.0
RPL26	-6636.0
RPL10A	-6644.0
MED23	-6699.0
HSP90AB1	-6702.0
TCF3	-6757.0
RPL34	-6807.0
ACVR1C	-6866.0
RPL41	-6877.0
RPS27A	-6894.0
SCN7A	-6911.0
RPLP2	-6915.0
DRAP1	-6924.0
SCN3B	-6980.0
RPL30	-6995.0
RPS19	-7037.0
RPL12	-7038.0
RPS11	-7122.0
TNF	-7241.0
LEF1	-7246.0
CDON	-7341.0
LHX4	-7363.0
SPTBN1	-7419.0
ARHGAP39	-7429.0
RPL36A	-7442.0
MED24	-7462.0
DAG1	-7502.0
RBM8A	-7527.0
PSMA8	-7559.0
PIAS2	-7624.0
RPS18	-7641.0
HES1	-7731.0
PLXNA3	-7769.0
RPS29	-7794.0
ZNF335	-7799.0
PSEN2	-7844.0
AJUBA	-7848.0
HOXA3	-7904.0
SCD5	-7947.0
SEMA6A	-7992.0
MED29	-8038.0
EFNA3	-8058.0
PLXNA1	-8064.0
RPL13A	-8123.0
NTN4	-8229.0
RPL35	-8239.0
DOK6	-8253.0
SMAD4	-8273.0
DLG1	-8338.0
UPF3B	-8397.0
SHANK3	-8441.0
RPL3	-8478.0
WNT1	-8531.0
MED10	-8659.0
FOXP1	-8687.0
CACNA1H	-8691.0
CACNG8	-8713.0
ADAM23	-8751.0
GFRA2	-8804.0
NRP1	-8872.0
KRT15	-8877.0
PAXIP1	-8884.0
PML	-8888.0
RPS20	-8922.0
DAB1	-8953.0
MED9	-8957.0
RPL39L	-8982.0
SRC	-9011.0
EFNA5	-9014.0
SEMA7A	-9049.0
MAGOHB	-9110.0
FOXO1	-9173.0
KRTAP5-1	-9214.0
ADAM11	-9250.0
GATA2	-9305.0
PSMC4	-9306.0
HELZ2	-9313.0
HOXA1	-9331.0
MED27	-9333.0
FARP2	-9364.0
CTCF	-9392.0
TRPC1	-9415.0
EED	-9417.0
RPL23A	-9477.0
HOXB2	-9489.0
GIT1	-9503.0
TRPC3	-9546.0
SEMA5A	-9572.0
NCBP2	-9624.0
MAPK8	-9646.0
RPS27	-9651.0
LDB1	-9701.0
PIK3R1	-9725.0
WNT10B	-9743.0
ABLIM2	-9888.0
EPHB1	-9914.0
ABLIM1	-9922.0
LAMA2	-9923.0
EZH2	-9929.0
ROBO3	-9931.0
NEO1	-9947.0
COL9A2	-9974.0
MED15	-9976.0
UPF3A	-10050.0
PERP	-10098.0
GSPT2	-10116.0
PSME1	-10138.0
ADGRG6	-10260.0
NELL2	-10334.0
NAB2	-10348.0
KAT2A	-10374.0
COL6A2	-10386.0
PSME2	-10415.0
ACVR2B	-10439.0
PLCG1	-10473.0
ARHGEF28	-10479.0
HOXC4	-10482.0
KMT2A	-10672.0
CACNA1C	-10711.0
ADAM22	-10880.0
PLXNA4	-10905.0
HSPA8	-10913.0
CACNB1	-10973.0
EFNB1	-10996.0
EPHA4	-11101.0
HOXB3	-11112.0
CDK4	-11138.0
RHOC	-11333.0
PSMB9	-11362.0
HOXB4	-11379.0
ACVR2A	-11411.0
SPTAN1	-11438.0
NCK1	-11488.0
RNPS1	-11511.0
SMAD3	-11541.0
PAK6	-11548.0
RPS6KA5	-11616.0
NCAM1	-11736.0
FYN	-11758.0
AGRN	-11794.0
AKT3	-11804.0
EZR	-11835.0
DLG3	-11848.0
PRKACB	-11857.0
UTRN	-11926.0
GATA6	-11955.0
GFI1	-11999.0
PIK3R3	-12037.0
PRKCQ	-12039.0
EVL	-12046.0
EOMES	-12061.0
RBBP7	-12085.0
YES1	-12143.0
KRT5	-12180.0
ERBB2	-12281.0
AKAP5	-12288.0
TFDP2	-12315.0
EPHA2	-12316.0

---

EPH-Ephrin signaling

	322
set	EPH-Ephrin signaling
setSize	79
pANOVA	1.33e-09
s.dist	0.394
p.adjustANOVA	3.43e-08

Top enriched genes

GeneID	Gene Rank
MMP9	9370
SDCBP	9367
ARPC1B	9303
ITSN1	9186
NCSTN	9139
ACTB	9060
CLTC	9056
CLTCL1	8939
ARPC1A	8923
RAC1	8720
ADAM10	8705
MYL6	8687
AP2M1	8673
ACTG1	8671
ARPC5	8653
EPHB3	8581
CLTA	8402
ARPC3	8309
PAK1	8252
CFL1	8242

Click HERE to show all gene set members

GeneID	Gene Rank
MMP9	9370
SDCBP	9367
ARPC1B	9303
ITSN1	9186
NCSTN	9139
ACTB	9060
CLTC	9056
CLTCL1	8939
ARPC1A	8923
RAC1	8720
ADAM10	8705
MYL6	8687
AP2M1	8673
ACTG1	8671
ARPC5	8653
EPHB3	8581
CLTA	8402
ARPC3	8309
PAK1	8252
CFL1	8242
PAK2	8226
RHOA	8218
LIMK2	8190
AP2S1	8080
ACTR3	7888
PSEN1	7843
ACTR2	7827
LYN	7728
MYL9	7719
ARPC4	7605
CDC42	7539
ARPC2	7449
ROCK1	7445
AP2A2	7360
MYL12A	6981
MYH9	6772
AP2A1	6628
APH1B	6248
EFNA4	6218
CLTB	6195
ROCK2	6151
PSENEN	5833
EPHB4	5397
SDC2	5257
MYL12B	5177
NCK2	5007
VAV3	4974
LIMK1	4741
PTK2	4506
EPHB2	4240
APH1A	4198
DNM1	3526
EFNA1	3122
RASA1	2134
TIAM1	701
MYH10	663
WASL	283
EPHB6	189
AP2B1	-2748
HRAS	-3335
MYH11	-3490
KALRN	-3725
VAV2	-4073
PAK3	-4194
ARHGEF7	-4627
EPHA1	-4744
EFNB2	-6280
PSEN2	-7844
EFNA3	-8058
SRC	-9011
EFNA5	-9014
GIT1	-9503
EPHB1	-9914
ARHGEF28	-10479
EFNB1	-10996
EPHA4	-11101
FYN	-11758
YES1	-12143
EPHA2	-12316

---

Golgi-to-ER retrograde transport

	469
set	Golgi-to-ER retrograde transport
setSize	111
pANOVA	1.85e-09
s.dist	0.33
p.adjustANOVA	4.68e-08

Top enriched genes

GeneID	Gene Rank
PLA2G4A	9234
ARF4	9201
KDELR1	9163
DCTN2	9158
ARF1	9083
RAB1A	9075
GALNT2	8896
NSF	8815
BICD2	8786
CAPZA2	8521
KIF3C	8451
RAB1B	8407
DCTN4	8385
COPA	8319
KIF1B	8290
RAB6A	8223
CAPZA1	8165
KIF5B	8144
CAPZB	8057
ARF5	7975

Click HERE to show all gene set members

GeneID	Gene Rank
PLA2G4A	9234
ARF4	9201
KDELR1	9163
DCTN2	9158
ARF1	9083
RAB1A	9075
GALNT2	8896
NSF	8815
BICD2	8786
CAPZA2	8521
KIF3C	8451
RAB1B	8407
DCTN4	8385
COPA	8319
KIF1B	8290
RAB6A	8223
CAPZA1	8165
KIF5B	8144
CAPZB	8057
ARF5	7975
COPB2	7965
TMED7	7909
RAB18	7893
KIF1C	7816
ARF3	7798
ACTR10	7652
COPG2	7636
DYNC1I2	7629
KDELR2	7585
COPG1	7533
KLC3	7479
COPB1	7399
DCTN6	7382
TMED9	7199
SURF4	7147
ACTR1A	7088
PAFAH1B2	7026
DYNC1LI1	6992
COPE	6979
GALNT1	6518
RAB6B	6149
TMED2	6098
DCTN3	6080
DYNLL1	6049
KIF13B	6047
SEC22B	5939
RAB3GAP1	5800
ARCN1	5661
KLC1	5596
KIF23	5584
PAFAH1B1	5534
KIF20A	5165
DCTN1	5143
STX18	4684
AGPAT3	4625
RAB3GAP2	4478
PAFAH1B3	4373
KIF9	4310
DYNC1LI2	4253
DYNC1I1	4211
NAPG	4190
COPZ1	4081
ARFGAP3	3807
KIF3B	3773
KIF4A	3763
RACGAP1	2921
KIF16B	2817
TMED3	2779
KIF27	2576
NAPA	1385
KIF6	1162
KIF11	950
USE1	922
KIF2C	812
CENPE	741
TMED10	328
NBAS	195
ZW10	37
KIF18B	-123
KIFC1	-166
KIF2A	-1080
KIFC2	-1555
ARFGAP1	-1962
KDELR3	-2154
KIF18A	-2744
NAPB	-2763
KIF15	-3246
DYNLL2	-4042
DCTN5	-4140
GBF1	-4322
KIF26A	-4564
ARFGAP2	-5850
KIF28P	-6736
KIF21B	-6771
BICD1	-7322
BNIP1	-7543
DYNC1H1	-7822
KIF20B	-7903
KLC4	-8231
KIF5C	-8297
KIF5A	-8378
KLC2	-8724
KIFAP3	-8777
RINT1	-10172
COPZ2	-11047
KIF19	-11579
KIF26B	-11671
KIF21A	-11830
KIF3A	-11957
PLA2G6	-12020
KIF22	-12286

---

Programmed Cell Death

	861
set	Programmed Cell Death
setSize	171
pANOVA	2.39e-09
s.dist	0.264
p.adjustANOVA	5.83e-08

Top enriched genes

GeneID	Gene Rank
H1-2	9553
VIM	9399
LMNB1	9391
YWHAG	9310
CD14	9164
MAPK3	9078
APAF1	9072
PRKCD	9012
YWHAE	9009
TLR4	8981
BMX	8978
LY96	8871
GSN	8805
BCL2L1	8798
HMGB2	8677
YWHAH	8621
UNC5A	8543
PSMB7	8535
TFDP1	8500
PSMD4	8498

Click HERE to show all gene set members

GeneID	Gene Rank
H1-2	9553
VIM	9399
LMNB1	9391
YWHAG	9310
CD14	9164
MAPK3	9078
APAF1	9072
PRKCD	9012
YWHAE	9009
TLR4	8981
BMX	8978
LY96	8871
GSN	8805
BCL2L1	8798
HMGB2	8677
YWHAH	8621
UNC5A	8543
PSMB7	8535
TFDP1	8500
PSMD4	8498
TNFRSF10B	8435
PSME3	8331
PPP3R1	8240
PAK2	8226
PSMB5	8188
STAT3	8152
PSMD6	7881
DBNL	7859
CASP9	7784
PSMD9	7712
CFLAR	7657
H1-0	7598
MAPK1	7520
PSMD2	7470
ROCK1	7445
DAPK2	7348
PSMA1	7346
BCL2L11	7326
PSMD1	7283
PSMB3	7265
MLKL	7247
PSMA7	7174
PSMC1	7096
BAD	7002
PSMB6	6927
SEPTIN4	6755
UBB	6737
DAPK1	6727
PSMF1	6724
PSMC6	6701
BCAP31	6618
PSMD12	6537
E2F1	6473
CTNNB1	6463
STK24	6408
YWHAB	6398
TICAM1	6380
PSMD11	6296
TICAM2	6244
BID	6075
DYNLL1	6049
PSMD7	6017
BAX	5996
PSMD13	5991
PSMA6	5978
PSMD8	5845
ADD1	5789
FADD	5746
YWHAZ	5687
TP53BP2	5594
PSMA2	5433
APIP	5064
CARD8	4781
BIRC2	4749
PSMD3	4693
PLEC	4691
DAPK3	4581
PTK2	4506
SEM1	4436
UBC	4421
NMT1	4400
BMF	4398
RIPK3	4262
TJP2	4183
PSMB2	4103
LMNA	3863
CLSPN	3790
FAS	3710
AKT1	3656
PSMD5	3507
PSMB1	3422
DFFA	3389
APC	3284
DNM1L	3048
H1-4	3026
OMA1	2996
UNC5B	2914
TNFSF10	2887
OPA1	2716
PSMD14	2703
PSMC2	2696
PSMB4	2552
KPNB1	2491
UACA	2196
PSMC3	2018
TNFRSF10A	1785
PSMD10	1646
SFN	1557
XIAP	1478
KPNA1	1320
UBA52	1071
ACIN1	844
APPL1	350
AKT2	345
CASP7	55
HMGB1	-200
BAK1	-321
CASP3	-499
PSMA4	-538
TRADD	-548
C1QBP	-902
PSMC5	-948
DSP	-1230
CYCS	-1282
OCLN	-2358
CASP6	-2858
PSMB8	-3080
DYNLL2	-4042
BCL2	-4480
TP73	-4805
CDKN2A	-5302
PSMA3	-5314
MAPT	-5444
FNTA	-5702
PSMB10	-5768
PSME4	-6099
PSMA5	-6154
TJP1	-6461
DIABLO	-6470
DFFB	-6760
RPS27A	-6894
YWHAQ	-7471
PSMA8	-7559
SATB1	-7601
BBC3	-7987
AVEN	-8172
GAS2	-8330
ARHGAP10	-8936
PSMC4	-9306
MAPK8	-9646
PSME1	-10138
PSME2	-10415
BIRC3	-10830
TP53	-10936
STK26	-10979
TP63	-11012
PMAIP1	-11074
RIPK1	-11184
PSMB9	-11362
SPTAN1	-11438
PPP1R13B	-11439
CASP8	-11463
CDH1	-11512
TRAF2	-11594
AKT3	-11804
PPP3CC	-12030
PRKCQ	-12039
MAGED1	-12172
GZMB	-12311
TFDP2	-12315
FASLG	-12319

---

COPI-mediated anterograde transport

	134
set	COPI-mediated anterograde transport
setSize	78
pANOVA	2.39e-09
s.dist	0.391
p.adjustANOVA	5.83e-08

Top enriched genes

GeneID	Gene Rank
SPTB	9250
ARF4	9201
KDELR1	9163
DCTN2	9158
CD55	9157
ARF1	9083
RAB1A	9075
ANK1	8897
NSF	8815
CAPZA2	8521
RAB1B	8407
DCTN4	8385
COPA	8319
CAPZA1	8165
CAPZB	8057
ARF5	7975
COPB2	7965
TMED7	7909
ARF3	7798
SPTA1	7785

Click HERE to show all gene set members

GeneID	Gene Rank
SPTB	9250
ARF4	9201
KDELR1	9163
DCTN2	9158
CD55	9157
ARF1	9083
RAB1A	9075
ANK1	8897
NSF	8815
CAPZA2	8521
RAB1B	8407
DCTN4	8385
COPA	8319
CAPZA1	8165
CAPZB	8057
ARF5	7975
COPB2	7965
TMED7	7909
ARF3	7798
SPTA1	7785
ACTR10	7652
COPG2	7636
DYNC1I2	7629
KDELR2	7585
COPG1	7533
COPB1	7399
DCTN6	7382
TMED9	7199
STX5	7186
ACTR1A	7088
DYNC1LI1	6992
COPE	6979
GORASP1	6670
GOLGA2	6217
TMED2	6098
DCTN3	6080
DYNLL1	6049
CD59	5964
ARCN1	5661
TMEM115	5605
YKT6	5277
DCTN1	5143
COG7	4321
DYNC1LI2	4253
DYNC1I1	4211
USO1	4192
NAPG	4190
COPZ1	4081
ARFGAP3	3807
TMED3	2779
NAPA	1385
TMED10	328
COG4	15
GOSR1	-160
COG8	-406
BET1	-631
GOSR2	-1504
ARFGAP1	-1962
KDELR3	-2154
NAPB	-2763
COG5	-3318
SPTBN5	-3449
DYNLL2	-4042
DCTN5	-4140
GBF1	-4322
ANK3	-4974
SPTBN2	-5189
COG3	-5230
GOLGB1	-5425
ARFGAP2	-5850
COG6	-5872
BET1L	-7385
SPTBN1	-7419
DYNC1H1	-7822
COG2	-8023
COPZ2	-11047
SPTAN1	-11438
COG1	-12057

---

Amyloid fiber formation

	70
set	Amyloid fiber formation
setSize	51
pANOVA	2.47e-09
s.dist	0.483
p.adjustANOVA	5.83e-08

Top enriched genes

GeneID	Gene Rank
SNCA	9421.0
H2BC21	9368.0
H2BC12	9178.0
FURIN	9162.0
NCSTN	9139.0
APP	9123.0
GSN	8805.0
H3-3A	8754.0
ADAM10	8705.0
SIAH2	8657.0
TGFBI	8304.0
H2BC5	8163.0
H2BC11	8076.0
H2AC6	8070.0
H2BC4	7549.0
H2BC17	7502.0
LYZ	7202.0
TSPAN14	7007.0
H3C15	6780.5
UBB	6737.0

Click HERE to show all gene set members

GeneID	Gene Rank
SNCA	9421.0
H2BC21	9368.0
H2BC12	9178.0
FURIN	9162.0
NCSTN	9139.0
APP	9123.0
GSN	8805.0
H3-3A	8754.0
ADAM10	8705.0
SIAH2	8657.0
TGFBI	8304.0
H2BC5	8163.0
H2BC11	8076.0
H2AC6	8070.0
H2BC4	7549.0
H2BC17	7502.0
LYZ	7202.0
TSPAN14	7007.0
H3C15	6780.5
UBB	6737.0
SORL1	6654.0
TSPAN33	6301.0
APH1B	6248.0
LTF	6182.0
H2AZ1	6126.0
ITM2B	6042.0
PSENEN	5833.0
USP9X	5542.0
H2BC9	5461.0
H2BC15	5458.0
H2AC20	5039.0
UBC	4421.0
APH1A	4198.0
GGA3	3846.0
MFGE8	3718.0
BACE1	3627.0
GGA1	2327.0
CST3	2157.0
UBA52	1071.0
TSPAN5	1049.0
NPPA	-569.0
TSPAN15	-1940.0
CALB1	-2900.0
SIAH1	-3004.0
NAT8B	-3928.0
H2BU1	-6519.0
GGA2	-6523.0
RPS27A	-6894.0
B2M	-7019.0
HSPG2	-7708.0
UBE2L6	-11415.0

---

Apoptosis

	79
set	Apoptosis
setSize	168
pANOVA	2.48e-09
s.dist	0.267
p.adjustANOVA	5.83e-08

Top enriched genes

GeneID	Gene Rank
H1-2	9553
VIM	9399
LMNB1	9391
YWHAG	9310
CD14	9164
MAPK3	9078
APAF1	9072
PRKCD	9012
YWHAE	9009
TLR4	8981
BMX	8978
LY96	8871
GSN	8805
BCL2L1	8798
HMGB2	8677
YWHAH	8621
UNC5A	8543
PSMB7	8535
TFDP1	8500
PSMD4	8498

Click HERE to show all gene set members

GeneID	Gene Rank
H1-2	9553
VIM	9399
LMNB1	9391
YWHAG	9310
CD14	9164
MAPK3	9078
APAF1	9072
PRKCD	9012
YWHAE	9009
TLR4	8981
BMX	8978
LY96	8871
GSN	8805
BCL2L1	8798
HMGB2	8677
YWHAH	8621
UNC5A	8543
PSMB7	8535
TFDP1	8500
PSMD4	8498
TNFRSF10B	8435
PSME3	8331
PPP3R1	8240
PAK2	8226
PSMB5	8188
STAT3	8152
PSMD6	7881
DBNL	7859
CASP9	7784
PSMD9	7712
CFLAR	7657
H1-0	7598
MAPK1	7520
PSMD2	7470
ROCK1	7445
DAPK2	7348
PSMA1	7346
BCL2L11	7326
PSMD1	7283
PSMB3	7265
PSMA7	7174
PSMC1	7096
BAD	7002
PSMB6	6927
SEPTIN4	6755
UBB	6737
DAPK1	6727
PSMF1	6724
PSMC6	6701
BCAP31	6618
PSMD12	6537
E2F1	6473
CTNNB1	6463
STK24	6408
YWHAB	6398
TICAM1	6380
PSMD11	6296
TICAM2	6244
BID	6075
DYNLL1	6049
PSMD7	6017
BAX	5996
PSMD13	5991
PSMA6	5978
PSMD8	5845
ADD1	5789
FADD	5746
YWHAZ	5687
TP53BP2	5594
PSMA2	5433
APIP	5064
CARD8	4781
BIRC2	4749
PSMD3	4693
PLEC	4691
DAPK3	4581
PTK2	4506
SEM1	4436
UBC	4421
NMT1	4400
BMF	4398
TJP2	4183
PSMB2	4103
LMNA	3863
CLSPN	3790
FAS	3710
AKT1	3656
PSMD5	3507
PSMB1	3422
DFFA	3389
APC	3284
DNM1L	3048
H1-4	3026
OMA1	2996
UNC5B	2914
TNFSF10	2887
OPA1	2716
PSMD14	2703
PSMC2	2696
PSMB4	2552
KPNB1	2491
UACA	2196
PSMC3	2018
TNFRSF10A	1785
PSMD10	1646
SFN	1557
XIAP	1478
KPNA1	1320
UBA52	1071
ACIN1	844
APPL1	350
AKT2	345
CASP7	55
HMGB1	-200
BAK1	-321
CASP3	-499
PSMA4	-538
TRADD	-548
C1QBP	-902
PSMC5	-948
DSP	-1230
CYCS	-1282
OCLN	-2358
CASP6	-2858
PSMB8	-3080
DYNLL2	-4042
BCL2	-4480
TP73	-4805
CDKN2A	-5302
PSMA3	-5314
MAPT	-5444
FNTA	-5702
PSMB10	-5768
PSME4	-6099
PSMA5	-6154
TJP1	-6461
DIABLO	-6470
DFFB	-6760
RPS27A	-6894
YWHAQ	-7471
PSMA8	-7559
SATB1	-7601
BBC3	-7987
AVEN	-8172
GAS2	-8330
ARHGAP10	-8936
PSMC4	-9306
MAPK8	-9646
PSME1	-10138
PSME2	-10415
TP53	-10936
STK26	-10979
TP63	-11012
PMAIP1	-11074
RIPK1	-11184
PSMB9	-11362
SPTAN1	-11438
PPP1R13B	-11439
CASP8	-11463
CDH1	-11512
TRAF2	-11594
AKT3	-11804
PPP3CC	-12030
PRKCQ	-12039
MAGED1	-12172
GZMB	-12311
TFDP2	-12315
FASLG	-12319

---

Autophagy

	97
set	Autophagy
setSize	124
pANOVA	2.6e-09
s.dist	0.31
p.adjustANOVA	6.02e-08

Top enriched genes

GeneID	Gene Rank
RNASE1	9528
PLIN3	9485
LAMTOR1	9450
GABARAPL2	9150
MTMR3	9105
PINK1	9054
CHMP2A	8863
RRAGD	8850
CHMP4B	8830
LAMP2	8803
UBAP1	8779
LAMTOR5	8611
HBB	8528
CHMP3	8339
PLIN2	8254
ATG3	8228
NBR1	8149
MAP1LC3B	8099
ATG7	8065
EPAS1	8002

Click HERE to show all gene set members

GeneID	Gene Rank
RNASE1	9528
PLIN3	9485
LAMTOR1	9450
GABARAPL2	9150
MTMR3	9105
PINK1	9054
CHMP2A	8863
RRAGD	8850
CHMP4B	8830
LAMP2	8803
UBAP1	8779
LAMTOR5	8611
HBB	8528
CHMP3	8339
PLIN2	8254
ATG3	8228
NBR1	8149
MAP1LC3B	8099
ATG7	8065
EPAS1	8002
MTMR14	7999
VPS37C	7973
GABARAP	7967
TSG101	7856
LAMTOR2	7704
LAMTOR3	7692
RHEB	7675
DYNC1I2	7629
MVB12A	7425
WIPI1	7320
MAP1LC3A	7204
ULK1	7143
DYNC1LI1	6992
VCP	6955
GFAP	6771
MFN2	6759
UBB	6737
VPS37A	6560
PARK7	6496
CSNK2A2	6430
BECN1	6423
RRAGA	6344
CSNK2A1	6207
HSF1	6139
ATG9A	6117
DYNLL1	6049
CHMP2B	5713
UBE2V1	5681
ATG10	5628
CHMP6	5590
PRKAG1	5582
WIPI2	5360
MVB12B	5251
RRAGC	5033
RB1CC1	4993
ATG4C	4659
LAMTOR4	4487
UBC	4421
VDAC1	4300
DYNC1LI2	4253
VPS28	4247
PEX5	4238
DYNC1I1	4211
SQSTM1	4123
CSNK2B	3987
VPS37B	3933
ATG101	3809
TOMM22	3446
WDR45	2969
SLC38A9	2861
CFTR	2738
CHMP4A	2480
TOMM6	2337
UBE2N	1951
PRKAG2	1942
PIK3C3	1626
WDR45B	1603
ATG5	1445
PRKAA1	1352
HSP90AA1	1348
PRKAB1	1302
UBA52	1071
USP30	853
ATG13	723
ATG4A	694
MLST8	304
RRAGB	-689
ATG12	-784
TSC2	-804
TOMM5	-1593
TSC1	-2097
IFT88	-2216
GABARAPL1	-2299
TOMM20	-2745
ARL13B	-3106
ATG4B	-3465
PIK3R4	-4040
DYNLL2	-4042
ATG4D	-4454
MFN1	-5002
TOMM7	-5059
EEF1A1	-5073
PGAM5	-5357
FUNDC1	-6104
HSP90AB1	-6702
MTERF3	-6802
RPS27A	-6894
DYNC1H1	-7822
TOMM40	-7957
PRKAB2	-8083
AMBRA1	-8242
CHMP7	-8325
HDAC6	-8348
TOMM70	-8631
SRC	-9011
UVRAG	-9200
ATG9B	-9347
MTOR	-9948
RPTOR	-10494
ATM	-10839
HSPA8	-10913
ATG16L1	-11792
ATG14	-11876
PCNT	-12109

---

Signaling by WNT

	1139
set	Signaling by WNT
setSize	254
pANOVA	3.12e-09
s.dist	0.216
p.adjustANOVA	7.1e-08

Top enriched genes

GeneID	Gene Rank
FZD5	9561
GNG10	9436
H2AJ	9418
SNX3	9383
H2BC21	9368
KREMEN1	9259
WNT11	9251
FRAT2	9218
H2BC12	9178
AGO4	9094
CLTC	9056
PLCB3	8999
GNG5	8866
FRAT1	8790
H3-3A	8754
RAC1	8720
TLE3	8679
AP2M1	8673
RNF146	8622
PSMB7	8535

Click HERE to show all gene set members

GeneID	Gene Rank
FZD5	9561.0
GNG10	9436.0
H2AJ	9418.0
SNX3	9383.0
H2BC21	9368.0
KREMEN1	9259.0
WNT11	9251.0
FRAT2	9218.0
H2BC12	9178.0
AGO4	9094.0
CLTC	9056.0
PLCB3	8999.0
GNG5	8866.0
FRAT1	8790.0
H3-3A	8754.0
RAC1	8720.0
TLE3	8679.0
AP2M1	8673.0
RNF146	8622.0
PSMB7	8535.0
ARRB2	8517.0
PSMD4	8498.0
CLTA	8402.0
PSME3	8331.0
PPP2CA	8308.0
GNB1	8278.0
PPP3R1	8240.0
GNB2	8234.0
RHOA	8218.0
WLS	8217.0
PSMB5	8188.0
H2BC5	8163.0
AP2S1	8080.0
H2BC11	8076.0
H2AC6	8070.0
PSMD6	7881.0
CSNK1A1	7813.0
PPP2CB	7769.0
PSMD9	7712.0
CTNNBIP1	7635.0
H2BC4	7549.0
H2BC17	7502.0
KLHL12	7485.0
PSMD2	7470.0
AP2A2	7360.0
PSMA1	7346.0
PSMD1	7283.0
PSMB3	7265.0
PSMA7	7174.0
GNB4	7138.0
PSMC1	7096.0
PRKCB	7056.0
TMED5	7010.0
PPP3CB	6998.0
PSMB6	6927.0
CUL3	6924.0
TLE4	6882.0
PPP2R5B	6870.0
PRKG1	6867.0
H3C15	6780.5
UBB	6737.0
GNAT2	6734.0
PSMF1	6724.0
GSK3B	6720.0
PSMC6	6701.0
AP2A1	6628.0
VPS26A	6625.0
VPS35	6616.0
GNG11	6612.0
FZD2	6552.0
PSMD12	6537.0
PIP5K1B	6526.0
CTNNB1	6463.0
CSNK2A2	6430.0
USP8	6383.0
PPP3CA	6327.0
PSMD11	6296.0
EP300	6208.0
CSNK2A1	6207.0
CLTB	6195.0
H2AZ1	6126.0
PSMD7	6017.0
PSMD13	5991.0
ASH2L	5989.0
PPP2R5A	5985.0
PSMA6	5978.0
ITPR2	5919.0
PSMD8	5845.0
SOX6	5735.0
DVL3	5734.0
YWHAZ	5687.0
AGO1	5660.0
PFN1	5562.0
H2BC9	5461.0
H2BC15	5458.0
PSMA2	5433.0
RAC2	5238.0
CDC73	5093.0
H2AC20	5039.0
SOX4	4870.0
SMARCA4	4789.0
WNT6	4753.0
PLCB2	4696.0
PSMD3	4693.0
PPP2R1A	4669.0
FZD1	4601.0
SEM1	4436.0
UBC	4421.0
SKP1	4349.0
GNG8	4339.0
LRP5	4241.0
CTBP2	4142.0
PSMB2	4103.0
RBX1	4039.0
CSNK2B	3987.0
ZRANB1	3772.0
KRAS	3760.0
AKT1	3656.0
DAAM1	3591.0
PSMD5	3507.0
NLK	3472.0
CREBBP	3460.0
PSMB1	3422.0
APC	3284.0
KMT2D	3244.0
VPS29	3218.0
AGO2	3046.0
LGR4	2759.0
PSMD14	2703.0
PSMC2	2696.0
PSMB4	2552.0
MAP3K7	2453.0
PPP2R5D	2440.0
MYC	2367.0
PRICKLE1	2258.0
WNT9B	2201.0
PSMC3	2018.0
CAV1	1856.0
PSMD10	1646.0
XIAP	1478.0
TERT	1447.0
KAT5	1361.0
PLCB1	1225.0
PRKCA	1163.0
UBA52	1071.0
DACT1	1044.0
RBBP5	1009.0
CSNK1G2	899.0
GNG3	894.0
LRP6	787.0
CHD8	642.0
GNB5	467.0
HDAC1	394.0
AKT2	345.0
KREMEN2	321.0
TCF7L1	265.0
LEO1	84.0
DVL1	61.0
WNT5B	-129.0
PARD6A	-224.0
PPP2R1B	-246.0
TNKS2	-512.0
PSMA4	-538.0
PPP2R5E	-627.0
USP34	-934.0
PSMC5	-948.0
AGO3	-1014.0
PDE6G	-1098.0
BCL9	-1175.0
ROR1	-1182.0
XPO1	-1199.0
H2AZ2	-1266.0
ZNRF3	-1808.0
CALM1	-2048.0
GNG4	-2175.0
PDE6A	-2208.0
SOX7	-2523.0
SMURF1	-2584.0
AP2B1	-2748.0
GNB3	-2776.0
SCRIB	-2871.0
WNT8B	-2910.0
PSMB8	-3080.0
RAC3	-3292.0
TCF4	-3878.0
WNT2B	-3983.0
WNT4	-4524.0
WNT9A	-4557.0
TNRC6B	-4558.0
WNT3	-4740.0
WNT16	-4891.0
BTRC	-4932.0
GNG7	-5049.0
PSMA3	-5314.0
TCF7L2	-5419.0
TNRC6A	-5567.0
PSMB10	-5768.0
TLE2	-5817.0
PSME4	-6099.0
PSMA5	-6154.0
FZD6	-6395.0
FZD7	-6496.0
H2BU1	-6519.0
CTBP1	-6549.0
TRRAP	-6755.0
FZD3	-6817.0
RPS27A	-6894.0
TLE1	-7036.0
WNT7A	-7231.0
FZD8	-7237.0
LEF1	-7246.0
AXIN2	-7434.0
ITPR1	-7553.0
PSMA8	-7559.0
CXXC4	-7734.0
GNG2	-7809.0
MEN1	-8265.0
WNT1	-8531.0
PRKG2	-8538.0
RUVBL1	-8726.0
TNKS	-8839.0
RYK	-9116.0
PSMC4	-9306.0
NFATC1	-9315.0
WNT10A	-9536.0
TCF7	-9694.0
WNT10B	-9743.0
CBY1	-9898.0
ITPR3	-9955.0
PORCN	-9992.0
GNAO1	-10133.0
PSME1	-10138.0
CSNK1E	-10239.0
SMURF2	-10250.0
AXIN1	-10310.0
PSME2	-10415.0
DVL2	-10753.0
PYGO2	-10903.0
AMER1	-11097.0
PDE6B	-11155.0
PSMB9	-11362.0
SOX13	-11374.0
PPP2R5C	-11413.0
CUL1	-11467.0
FZD4	-11733.0
TNRC6C	-11737.0
TLE5	-11797.0
BCL9L	-11860.0
MOV10	-11980.0
CCDC88C	-12005.0
RNF43	-12040.0
GNGT2	-12070.0
LGR6	-12255.0
RUNX3	-12312.0

---

RHO GTPases activate PKNs

	894
set	RHO GTPases activate PKNs
setSize	48
pANOVA	6.59e-09
s.dist	0.484
p.adjustANOVA	1.47e-07

Top enriched genes

GeneID	Gene Rank
H2AJ	9418.0
H2BC21	9368.0
YWHAG	9310.0
H2BC12	9178.0
YWHAE	9009.0
H3-3A	8754.0
RAC1	8720.0
MYL6	8687.0
YWHAH	8621.0
PAK1	8252.0
RHOA	8218.0
H2BC5	8163.0
H2BC11	8076.0
H2AC6	8070.0
MYL9	7719.0
H2BC4	7549.0
H2BC17	7502.0
PPP1CB	7093.0
PPP1R14A	7009.0
H3C15	6780.5

Click HERE to show all gene set members

GeneID	Gene Rank
H2AJ	9418.0
H2BC21	9368.0
YWHAG	9310.0
H2BC12	9178.0
YWHAE	9009.0
H3-3A	8754.0
RAC1	8720.0
MYL6	8687.0
YWHAH	8621.0
PAK1	8252.0
RHOA	8218.0
H2BC5	8163.0
H2BC11	8076.0
H2AC6	8070.0
MYL9	7719.0
H2BC4	7549.0
H2BC17	7502.0
PPP1CB	7093.0
PPP1R14A	7009.0
H3C15	6780.5
MYH9	6772.0
YWHAB	6398.0
PDPK1	6209.0
PPP1R12A	6131.0
H2AZ1	6126.0
YWHAZ	5687.0
H2BC9	5461.0
H2BC15	5458.0
MYL12B	5177.0
H2AC20	5039.0
CDC25C	5024.0
AR	4913.0
KLK2	3082.0
PPP1R12B	1737.0
SFN	1557.0
RHOB	1190.0
NCOA2	1109.0
MYH10	663.0
PKN2	151.0
H2AZ2	-1266.0
PKN1	-1986.0
MYH11	-3490.0
PKN3	-3714.0
H2BU1	-6519.0
YWHAQ	-7471.0
KDM1A	-9476.0
KDM4C	-10513.0
RHOC	-11333.0

---

ROS and RNS production in phagocytes

	925
set	ROS and RNS production in phagocytes
setSize	31
pANOVA	7.98e-09
s.dist	0.598
p.adjustANOVA	1.75e-07

Top enriched genes

GeneID	Gene Rank
ATP6V0A1	9483
NCF4	9365
ATP6V1A	9301
ATP6V0D1	9298
NCF2	9209
SLC11A1	9152
ATP6V1D	9118
ATP6V0C	9113
ATP6V1B2	9005
CYBB	9000
ATP6V0B	8701
ATP6V0E1	8662
ATP6V1C1	8628
ATP6V1H	8119
ATP6V1E1	8107
NCF1	7433
MPO	7364
TCIRG1	7266
CYBA	6952
LPO	6576

Click HERE to show all gene set members

GeneID	Gene Rank
ATP6V0A1	9483
NCF4	9365
ATP6V1A	9301
ATP6V0D1	9298
NCF2	9209
SLC11A1	9152
ATP6V1D	9118
ATP6V0C	9113
ATP6V1B2	9005
CYBB	9000
ATP6V0B	8701
ATP6V0E1	8662
ATP6V1C1	8628
ATP6V1H	8119
ATP6V1E1	8107
NCF1	7433
MPO	7364
TCIRG1	7266
CYBA	6952
LPO	6576
ATP6V1F	5949
ATP6V1E2	5776
RAC2	5238
HVCN1	4848
ATP6V1G1	3989
NOS1	1401
NOS3	-1718
ATP6V1C2	-2222
ATP6V1G2	-9275
ATP6V0E2	-11475
ATP6V0A2	-12193

---

MyD88-independent TLR4 cascade

	688
set	MyD88-independent TLR4 cascade
setSize	96
pANOVA	8.8e-09
s.dist	0.34
p.adjustANOVA	1.88e-07

Top enriched genes

GeneID	Gene Rank
S100A12	9567
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
UBE2D1	9125
APP	9123
MAPK3	9078
MAP2K6	9010
TLR4	8981
MAP2K1	8960
LY96	8871
MAP2K3	8785
UBE2D3	8710
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
MEF2A	8030
CHUK	7959
RPS6KA1	7800

Click HERE to show all gene set members

GeneID	Gene Rank
S100A12	9567
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
UBE2D1	9125
APP	9123
MAPK3	9078
MAP2K6	9010
TLR4	8981
MAP2K1	8960
LY96	8871
MAP2K3	8785
UBE2D3	8710
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
MEF2A	8030
CHUK	7959
RPS6KA1	7800
PPP2CB	7769
MAPK1	7520
TANK	7494
TAB2	7070
MAP2K4	6948
NFKBIA	6835
UBB	6737
TICAM1	6380
NFKB1	6367
FBXW11	6282
MAP3K8	6262
TICAM2	6244
FOS	6179
IRAK1	6159
ATF1	5790
FADD	5746
TAB1	5711
UBE2V1	5681
TNIP2	5630
IKBKG	5434
PTPN11	5383
IKBKE	4779
BIRC2	4749
UBE2D2	4721
PPP2R1A	4669
UBC	4421
DUSP6	4367
SKP1	4349
RIPK3	4262
MAPKAPK2	4176
MAPK10	4136
JUN	3964
MAPK11	3955
RPS6KA2	3177
TAB3	3165
TBK1	3159
RPS6KA3	3012
MAP3K7	2453
PPP2R5D	2440
ATF2	2110
UBE2N	1951
MAP2K7	1647
AGER	1309
VRK3	1293
UBA52	1071
RIPK2	1042
ELK1	1040
NKIRAS1	387
NFKBIB	-88
HMGB1	-200
TRAF6	-241
PPP2R1B	-246
MEF2C	-319
NFKB2	-865
MAPK7	-1294
CREB1	-1382
RELA	-1807
DUSP7	-3253
BTRC	-4932
S100B	-5025
IKBKB	-5290
TRAF3	-5296
DUSP4	-6432
RPS27A	-6894
MAPK9	-7182
IRF3	-8479
IRF7	-8889
MAPK8	-9646
IRAK2	-9718
BIRC3	-10830
RIPK1	-11184
CASP8	-11463
CUL1	-11467
RPS6KA5	-11616
SARM1	-11973
NOD1	-12234

---

TRIF(TICAM1)-mediated TLR4 signaling

	1215
set	TRIF(TICAM1)-mediated TLR4 signaling
setSize	96
pANOVA	8.8e-09
s.dist	0.34
p.adjustANOVA	1.88e-07

Top enriched genes

GeneID	Gene Rank
S100A12	9567
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
UBE2D1	9125
APP	9123
MAPK3	9078
MAP2K6	9010
TLR4	8981
MAP2K1	8960
LY96	8871
MAP2K3	8785
UBE2D3	8710
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
MEF2A	8030
CHUK	7959
RPS6KA1	7800

Click HERE to show all gene set members

GeneID	Gene Rank
S100A12	9567
DUSP3	9324
NKIRAS2	9308
MAPK14	9219
CD14	9164
UBE2D1	9125
APP	9123
MAPK3	9078
MAP2K6	9010
TLR4	8981
MAP2K1	8960
LY96	8871
MAP2K3	8785
UBE2D3	8710
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
MEF2A	8030
CHUK	7959
RPS6KA1	7800
PPP2CB	7769
MAPK1	7520
TANK	7494
TAB2	7070
MAP2K4	6948
NFKBIA	6835
UBB	6737
TICAM1	6380
NFKB1	6367
FBXW11	6282
MAP3K8	6262
TICAM2	6244
FOS	6179
IRAK1	6159
ATF1	5790
FADD	5746
TAB1	5711
UBE2V1	5681
TNIP2	5630
IKBKG	5434
PTPN11	5383
IKBKE	4779
BIRC2	4749
UBE2D2	4721
PPP2R1A	4669
UBC	4421
DUSP6	4367
SKP1	4349
RIPK3	4262
MAPKAPK2	4176
MAPK10	4136
JUN	3964
MAPK11	3955
RPS6KA2	3177
TAB3	3165
TBK1	3159
RPS6KA3	3012
MAP3K7	2453
PPP2R5D	2440
ATF2	2110
UBE2N	1951
MAP2K7	1647
AGER	1309
VRK3	1293
UBA52	1071
RIPK2	1042
ELK1	1040
NKIRAS1	387
NFKBIB	-88
HMGB1	-200
TRAF6	-241
PPP2R1B	-246
MEF2C	-319
NFKB2	-865
MAPK7	-1294
CREB1	-1382
RELA	-1807
DUSP7	-3253
BTRC	-4932
S100B	-5025
IKBKB	-5290
TRAF3	-5296
DUSP4	-6432
RPS27A	-6894
MAPK9	-7182
IRF3	-8479
IRF7	-8889
MAPK8	-9646
IRAK2	-9718
BIRC3	-10830
RIPK1	-11184
CASP8	-11463
CUL1	-11467
RPS6KA5	-11616
SARM1	-11973
NOD1	-12234

---

Generic Transcription Pathway

	446
set	Generic Transcription Pathway
setSize	1085
pANOVA	9.34e-09
s.dist	-0.103
p.adjustANOVA	1.96e-07

Top enriched genes

GeneID	Gene Rank
FASLG	-12319
TFDP2	-12315
RUNX3	-12312
ERBB2	-12281
NFATC2	-12236
YES1	-12143
GATA3	-12140
PTPN4	-12133
RAD1	-12131
ZNF599	-12123
AUTS2	-12091
RBBP7	-12085
ZNF3	-12084
ZNF287	-12042
PRKCQ	-12039
MDC1	-11988
MOV10	-11980
RPA1	-11962
WRN	-11954
FANCI	-11952

Click HERE to show all gene set members

GeneID	Gene Rank
FASLG	-12319.0
TFDP2	-12315.0
RUNX3	-12312.0
ERBB2	-12281.0
NFATC2	-12236.0
YES1	-12143.0
GATA3	-12140.0
PTPN4	-12133.0
RAD1	-12131.0
ZNF599	-12123.0
AUTS2	-12091.0
RBBP7	-12085.0
ZNF3	-12084.0
ZNF287	-12042.0
PRKCQ	-12039.0
MDC1	-11988.0
MOV10	-11980.0
RPA1	-11962.0
WRN	-11954.0
FANCI	-11952.0
PRR5	-11948.0
TP53RK	-11910.0
SMAD7	-11905.0
ZNF74	-11899.0
ZNF461	-11892.0
ZNF530	-11884.0
NUAK1	-11875.0
RORA	-11872.0
ANAPC1	-11870.0
DLL1	-11843.0
ZNF250	-11834.0
ZNF43	-11824.0
DGCR8	-11822.0
AKT3	-11804.0
ZNF70	-11798.0
ZNF620	-11789.0
STAT1	-11769.0
ZNF682	-11765.0
RFC5	-11754.0
ZNF33B	-11744.0
TNRC6C	-11737.0
CAMK2D	-11728.0
BRIP1	-11720.0
ZNF554	-11703.0
GLS	-11674.0
ZNF571	-11667.0
ZNF724	-11663.0
CCNE1	-11655.0
CCND2	-11649.0
ZNF500	-11640.0
SMARCD1	-11632.0
ZNF696	-11623.0
ZNF286A	-11614.0
DDB2	-11598.0
PARP1	-11586.0
ZNF607	-11570.0
ZNF570	-11563.0
ZNF496	-11561.0
ZNF549	-11552.0
ZNF707	-11550.0
SMAD3	-11541.0
ZNF736	-11535.0
ZNF568	-11528.0
RAD9A	-11491.0
DYRK2	-11483.0
FANCD2	-11476.0
ZNF337	-11474.0
FANCC	-11469.0
CUL1	-11467.0
KRBOX4	-11462.0
SUPT16H	-11458.0
ZNF136	-11442.0
PPP1R13B	-11439.0
ZNF517	-11424.0
ZNF569	-11423.0
PPP2R5C	-11413.0
ZNF660	-11407.0
JMY	-11399.0
CNOT6L	-11389.0
PIP4K2C	-11384.0
ATRIP	-11383.0
ZNF773	-11369.0
PSMB9	-11362.0
ZNF383	-11353.0
CDC23	-11349.0
ZNF30	-11348.0
MSH2	-11345.0
ZNF138	-11338.0
CENPJ	-11318.0
ZNF600	-11316.0
NR2C2AP	-11291.0
ZNF235	-11279.0
ZNF566	-11273.0
ZNF584	-11267.0
RUNX2	-11254.0
RAD51D	-11245.0
ZNF510	-11232.0
ZNF211	-11220.0
SSRP1	-11213.0
ZNF740	-11211.0
ZNF75D	-11190.0
ZKSCAN8	-11169.0
WWOX	-11144.0
ZNF621	-11141.0
CDK4	-11138.0
ZNF184	-11134.0
ZNF133	-11132.0
ZNF324B	-11124.0
ZNF703	-11109.0
ANAPC5	-11108.0
ZNF77	-11103.0
ZNF519	-11102.0
ZNF19	-11100.0
ZNF432	-11099.0
ZFP30	-11090.0
COX11	-11085.0
PMAIP1	-11074.0
PCBP4	-11068.0
ZNF419	-11053.0
ZNF14	-11045.0
ZNF678	-11040.0
ZNF202	-11038.0
KIT	-11031.0
ITGAL	-11015.0
TP63	-11012.0
ITGA4	-11003.0
ZNF343	-11001.0
ZNF649	-10999.0
ZNF551	-10985.0
SKI	-10980.0
ZNF528	-10971.0
MECP2	-10955.0
BRD1	-10953.0
ZNF441	-10950.0
TP53	-10936.0
ZNF354C	-10918.0
PLXNA4	-10905.0
ZNF226	-10869.0
ATAD2	-10863.0
ZNF550	-10852.0
ATM	-10839.0
ZNF257	-10808.0
FBXO32	-10797.0
ZNF548	-10776.0
L3MBTL2	-10749.0
ZNF180	-10717.0
KMT2A	-10672.0
MAF	-10649.0
SIN3A	-10648.0
ZIK1	-10637.0
ZFP1	-10623.0
ZNF540	-10616.0
PRMT6	-10611.0
ZNF595	-10604.0
ZNF585B	-10585.0
DAXX	-10582.0
CTLA4	-10563.0
ZNF248	-10556.0
RFC3	-10515.0
RFC4	-10511.0
ZNF778	-10506.0
ZNF10	-10497.0
RPTOR	-10494.0
ZNF790	-10490.0
ZNF253	-10486.0
ZNF23	-10475.0
ZNF302	-10462.0
ZNF563	-10454.0
ZNF675	-10432.0
PSME2	-10415.0
ATR	-10403.0
ZFPM1	-10381.0
KAT2A	-10374.0
ZNF92	-10345.0
IFNG	-10320.0
ZNF544	-10316.0
AXIN1	-10310.0
NR3C2	-10304.0
ZNF680	-10298.0
ZNF446	-10293.0
SMURF2	-10250.0
ZNF529	-10241.0
RAD17	-10231.0
ZNF334	-10201.0
ABCA6	-10189.0
ZNF212	-10183.0
ZNF266	-10178.0
ZNF799	-10164.0
ZNF749	-10139.0
PSME1	-10138.0
ZNF626	-10123.0
SMYD2	-10122.0
LRPPRC	-10120.0
RBL1	-10115.0
ZFP14	-10110.0
NR1D2	-10102.0
PERP	-10098.0
ZNF26	-10097.0
ZNF311	-10093.0
EPC1	-10064.0
ZNF420	-10042.0
WWP1	-10036.0
ZNF224	-10000.0
GPAM	-9993.0
ZNF596	-9991.0
ING5	-9987.0
MED15	-9976.0
MGA	-9961.0
NFYB	-9957.0
MTOR	-9948.0
TGIF2	-9946.0
EZH2	-9929.0
HEY2	-9918.0
ZNF704	-9866.0
SCO1	-9862.0
ZNF45	-9813.0
ZNF112	-9809.0
TXNIP	-9792.0
BMI1	-9787.0
ZNF684	-9785.0
ZNF483	-9777.0
ZNF473	-9775.0
NR2C1	-9766.0
ZNF689	-9765.0
ZNF664	-9754.0
ZNF583	-9745.0
ZNF737	-9744.0
LDB1	-9701.0
TCF7	-9694.0
ZFP90	-9691.0
ZNF227	-9671.0
IGFBP3	-9669.0
ZNF431	-9661.0
ZNF708	-9652.0
ZFP69	-9639.0
ZNF436	-9614.0
NPM1	-9596.0
RICTOR	-9593.0
CCNT1	-9570.0
ZNF41	-9557.0
ZNF324	-9551.0
TRPC3	-9546.0
ZNF263	-9538.0
ZNF484	-9505.0
NOP2	-9504.0
BRD2	-9501.0
ZNF157	-9485.0
ZSCAN25	-9474.0
ZNF625	-9473.0
CHD3	-9466.0
ZNF597	-9462.0
ZNF793	-9461.0
ZNF470	-9441.0
EED	-9417.0
ZNF506	-9375.0
ZNF614	-9373.0
ZNF354B	-9371.0
ZNF573	-9339.0
MED27	-9333.0
PSMC4	-9306.0
GATA2	-9305.0
ZNF727	-9280.0
ESR2	-9236.0
ESR1	-9230.0
ZNF582	-9222.0
TBP	-9220.0
CAMK4	-9185.0
FOXO1	-9173.0
ZNF699	-9166.0
ZNF160	-9158.0
CBX5	-9139.0
ZNF767P	-9099.0
ZNF782	-9087.0
SESN1	-9083.0
SMARCC1	-9046.0
ZNF738	-9015.0
SRC	-9011.0
RPA3	-9003.0
ZNF677	-8997.0
ZNF17	-8990.0
ZNF433	-8940.0
TRIM33	-8937.0
ZNF606	-8924.0
PRDM1	-8919.0
ZNF485	-8908.0
ZNF79	-8907.0
ZNF619	-8897.0
PRMT1	-8894.0
PML	-8888.0
ZNF721	-8881.0
SIRT3	-8860.0
MNAT1	-8852.0
ZNF317	-8848.0
ZNF440	-8835.0
ZNF439	-8834.0
ZNF792	-8833.0
ZNF567	-8797.0
ZNF416	-8770.0
EHMT1	-8729.0
ZNF140	-8719.0
ZNF141	-8708.0
ZNF717	-8704.0
AIFM2	-8680.0
NR2C2	-8678.0
TGIF1	-8667.0
MED10	-8659.0
FOXP3	-8628.0
NR1D1	-8603.0
ZNF709	-8595.0
TAF1	-8536.0
CDK13	-8535.0
ZNF559	-8520.0
EHMT2	-8517.0
ZNF331	-8509.0
ZNF681	-8462.0
MAPKAPK5	-8452.0
L3MBTL1	-8405.0
ZNF234	-8374.0
HDAC6	-8348.0
ZNF300	-8316.0
E2F5	-8308.0
SKP2	-8307.0
CDKN1B	-8305.0
SMAD4	-8273.0
RORC	-8272.0
MEN1	-8265.0
MEAF6	-8251.0
ZNF274	-8227.0
GLI3	-8180.0
ZFP37	-8177.0
PHC3	-8154.0
ZNF665	-8087.0
PRKAB2	-8083.0
ZNF720	-8047.0
ZKSCAN3	-8032.0
ZNF641	-8025.0
ZNF688	-8012.0
BBC3	-7987.0
ZNF521	-7954.0
CDC7	-7896.0
ZNF726	-7894.0
MRE11	-7888.0
TAF4B	-7865.0
TNFRSF18	-7833.0
PHC1	-7816.0
ZNF702P	-7783.0
HES1	-7731.0
ZNF175	-7723.0
ERCC3	-7721.0
PIP4K2B	-7720.0
ZNF320	-7709.0
ZNF273	-7685.0
ZNF791	-7659.0
ZNF75A	-7592.0
ZNF2	-7584.0
GLS2	-7572.0
ZNF585A	-7564.0
PSMA8	-7559.0
ZNF671	-7555.0
ZNF264	-7539.0
RGCC	-7511.0
RBM14	-7496.0
RAD50	-7482.0
YWHAQ	-7471.0
MED24	-7462.0
ACTL6A	-7411.0
TAF6	-7402.0
ZNF195	-7382.0
YAF2	-7372.0
MTA2	-7367.0
ZNF771	-7328.0
IL2RA	-7301.0
ANAPC2	-7284.0
RBL2	-7257.0
LEF1	-7246.0
BRPF1	-7223.0
ZNF12	-7194.0
ZNF577	-7167.0
ZNF382	-7116.0
ZNF777	-7081.0
ZNF425	-6990.0
ZNF785	-6950.0
ZNF786	-6944.0
ZNF268	-6940.0
COX19	-6928.0
RPS27A	-6894.0
MLH1	-6878.0
ZNF418	-6875.0
CCND1	-6847.0
ZNF711	-6820.0
ANAPC4	-6780.0
GAMT	-6775.0
NR4A1	-6762.0
TCF3	-6757.0
SUPT5H	-6744.0
ZNF33A	-6730.0
ZNF223	-6729.0
FBXW7	-6709.0
MED23	-6699.0
GAD2	-6686.0
ZNF764	-6661.0
ZNF415	-6651.0
PIDD1	-6606.0
ZKSCAN7	-6571.0
ZFP28	-6554.0
TAF15	-6541.0
RHNO1	-6524.0
H2BU1	-6519.0
BRPF3	-6480.0
ZNF135	-6472.0
FOXO6	-6467.0
TJP1	-6461.0
ZNF616	-6426.0
RPA2	-6397.0
ZNF480	-6393.0
CDK6	-6379.0
THRA	-6373.0
TFAP2E	-6342.0
AGRP	-6298.0
NELFCD	-6291.0
ZNF691	-6276.0
ZNF442	-6252.0
WWTR1	-6206.0
ZNF610	-6187.0
KMT2E	-6165.0
RNF34	-6162.0
PSMA5	-6154.0
ZNF208	-6140.0
ZNF706	-6138.0
COX18	-6129.0
PSME4	-6099.0
PPARD	-6092.0
ZNF557	-6048.0
PCNA	-6038.0
CDC16	-6037.0
ZNF169	-6034.0
TAF2	-5999.0
ZNF543	-5993.0
ZNF398	-5917.0
E2F7	-5910.0
NOC2L	-5908.0
ZNF493	-5903.0
ZNF662	-5826.0
PSMB10	-5768.0
ZNF718	-5691.0
ZNF713	-5662.0
SETD1A	-5656.0
ZNF101	-5620.0
ZNF761	-5594.0
ZNF71	-5593.0
PMS2	-5588.0
ZNF154	-5579.0
TNRC6A	-5567.0
ZNF34	-5557.0
SCMH1	-5553.0
KRBA1	-5549.0
ARID1B	-5542.0
ZFP69B	-5536.0
MED30	-5533.0
ZNF658	-5480.0
ZNF514	-5474.0
ZNF25	-5449.0
TNKS1BP1	-5439.0
TCF7L2	-5419.0
BLK	-5390.0
ZNF99	-5340.0
ZNF589	-5337.0
PSMA3	-5314.0
CDKN2A	-5302.0
ZNF37A	-5273.0
ANAPC7	-5259.0
RABGGTB	-5240.0
ZNF615	-5239.0
ZKSCAN4	-5210.0
BTG1	-5204.0
NOTCH4	-5200.0
ZNF547	-5191.0
CCNT2	-5173.0
ZNF443	-5161.0
NR4A3	-5131.0
PPARGC1B	-5117.0
ANAPC10	-5074.0
ZNF285	-5070.0
COX20	-5036.0
CDK2	-5018.0
ZNF155	-5007.0
ZNF124	-5001.0
ZNF417	-4959.0
E2F6	-4946.0
SOCS4	-4914.0
TRIM28	-4905.0
ZNF430	-4872.0
RARG	-4816.0
TP73	-4805.0
MAMLD1	-4791.0
ZNF700	-4784.0
ZNF546	-4775.0
BLM	-4764.0
ZNF611	-4733.0
CBX2	-4693.0
RBBP8	-4692.0
ZNF492	-4637.0
CHD4	-4576.0
TNRC6B	-4558.0
ZNF564	-4521.0
ZNF460	-4514.0
TAF5	-4458.0
ZNF197	-4453.0
ZNF426	-4438.0
CHEK2	-4375.0
SMARCE1	-4337.0
ZNF561	-4324.0
CNOT1	-4305.0
SCO2	-4299.0
ZNF692	-4253.0
NR1I2	-4247.0
SIRT1	-4217.0
SIN3B	-4201.0
PCGF2	-4179.0
SMARCC2	-4163.0
MED1	-4082.0
POLR2D	-4058.0
RMI2	-4057.0
RING1	-4045.0
ZNF233	-4022.0
ZNF486	-3995.0
CDK9	-3988.0
ARID2	-3959.0
YEATS4	-3942.0
CNOT7	-3875.0
ZNF215	-3859.0
NELFA	-3858.0
SMARCB1	-3855.0
PRELID3A	-3846.0
ZNF676	-3634.0
ZNF701	-3602.0
SESN3	-3595.0
BCL2L14	-3588.0
GPX2	-3560.0
ZSCAN32	-3495.0
CASP10	-3491.0
TOPBP1	-3486.0
ZNF556	-3483.0
ZNF655	-3451.0
BARD1	-3441.0
NR1H3	-3418.0
PCGF5	-3397.0
ZNF350	-3381.0
PAX5	-3344.0
ZNF624	-3331.0
ZNF714	-3329.0
UXT	-3286.0
PIN1	-3272.0
RXRB	-3221.0
POLR2A	-3105.0
PSMB8	-3080.0
ZNF221	-3044.0
ZFP2	-3007.0
GTF2H1	-2929.0
ZNF670	-2911.0
GTF2H4	-2906.0
TAF11	-2897.0
DNA2	-2882.0
CASP6	-2858.0
POLR2H	-2817.0
CTSV	-2816.0
HIVEP3	-2800.0
PLK2	-2772.0
RAD51	-2740.0
ZNF555	-2734.0
SMARCA2	-2716.0
CNOT10	-2690.0
ZNF490	-2614.0
TAF9B	-2602.0
TTC5	-2589.0
SMURF1	-2584.0
ZNF18	-2547.0
POLR2B	-2536.0
CHEK1	-2534.0
ZNF605	-2515.0
CASP2	-2478.0
ZNF772	-2476.0
RABGGTA	-2455.0
SUZ12	-2444.0
KAT2B	-2393.0
OCLN	-2358.0
PIP4K2A	-2339.0
ZNF839	-2260.0
FZR1	-2253.0
GTF2H3	-2247.0
ANAPC16	-2165.0
CNOT2	-2108.0
TSC1	-2097.0
CALM1	-2048.0
CDK8	-1997.0
ZNF860	-1966.0
RBBP4	-1907.0
PHF20	-1870.0
KCTD1	-1854.0
TAF3	-1820.0
HSPD1	-1809.0
RELA	-1807.0
POLR2K	-1792.0
GATAD2B	-1780.0
RFFL	-1730.0
TAF4	-1726.0
NR2F1	-1708.0
ZNF468	-1707.0
ZNF669	-1696.0
ZNF28	-1676.0
DDIT4	-1660.0
NR4A2	-1625.0
EXO1	-1572.0
COX14	-1508.0
BGLAP	-1498.0
CREB1	-1382.0
CDK12	-1370.0
ZNF750	-1367.0
CNOT4	-1306.0
CYCS	-1282.0
SETD9	-1269.0
TCF12	-1268.0
H2AZ2	-1266.0
H19	-1263.0
MDM4	-1218.0
CDK5R1	-1166.0
STUB1	-1093.0
ZNF627	-1060.0
AGO3	-1014.0
ZNF565	-953.0
TCEA1	-951.0
PSMC5	-948.0
GPS2	-914.0
ZNF562	-896.0
MED6	-888.0
TSC2	-804.0
MOBP	-750.0
UBE2I	-746.0
PCGF6	-708.0
RRAGB	-689.0
CDC27	-659.0
SKIL	-606.0
ZNF558	-592.0
NPPA	-569.0
MBD3	-546.0
PSMA4	-538.0
ZNF716	-511.0
MAML2	-476.0
MEF2C	-319.0
PPP2R1B	-246.0
MED14	-205.0
RRM2	-188.0
ZNF587	-183.0
ZNF200	-170.0
HUS1	-131.0
ZNF222	-72.0
BRD7	-36.0
ZNF347	-33.0
KLF4	11.0
MT-CO2	35.0
MT-CO3	47.0
KMT2C	71.0
APOE	103.0
WDR5	123.0
MED7	178.0
COX16	214.0
ABL1	229.0
TRIAP1	238.0
TCF7L1	265.0
MLST8	304.0
POLR2I	316.0
AKT2	345.0
ZNF100	353.0
ZNF776	366.0
NELFB	385.0
HDAC1	394.0
PPP1R13L	418.0
CCNB1	460.0
PLAGL1	465.0
CSF1R	487.0
YY1	529.0
MYB	555.0
COX7C	558.0
CCNA1	575.0
TEAD2	599.0
NR3C1	600.0
BANP	649.0
MT-CO1	675.0
CLDN5	702.0
COX6C	721.0
SETD1B	751.0
KAT6A	764.0
CCNH	783.0
PPARA	865.0
AURKB	959.0
RBBP5	1009.0
ZNF429	1060.0
UBA52	1071.0
KMT2B	1204.0
GCK	1242.0
TAF9	1249.0
PRKAB1	1302.0
ZNF394	1327.0
HDAC9	1347.0
PRKAA1	1352.0
KAT5	1361.0
ITCH	1394.0
ZKSCAN5	1418.0
CDK1	1480.0
MED31	1486.0
POLR2C	1531.0
SFN	1557.0
THRB	1600.0
ATXN3	1623.0
PSMD10	1646.0
ELF1	1662.0
CCNA2	1676.0
KCTD15	1753.0
TNFRSF10A	1785.0
TPX2	1833.0
CAV1	1856.0
CCNC	1883.0
CAMK2G	1888.0
ZNF658B	1910.0
NR1I3	1915.0
ZNF613	1941.0
PRKAG2	1942.0
TAF7	1986.0
PSMC3	2018.0
MED12	2042.0
PVALB	2049.0
CNOT11	2103.0
ATF2	2110.0
CBFB	2152.0
OPRM1	2186.0
ZKSCAN1	2205.0
CBX4	2237.0
STK11	2241.0
NBN	2243.0
CHM	2291.0
HDAC10	2302.0
MYC	2367.0
MYBL2	2543.0
PSMB4	2552.0
MED13	2566.0
ELF2	2628.0
DEK	2655.0
PSMC2	2696.0
ZNF586	2702.0
PSMD14	2703.0
NRBP1	2851.0
SLC38A9	2861.0
BTG2	2864.0
E2F8	2873.0
ZNF471	2905.0
CCNK	2936.0
VENTX	2938.0
POMC	2971.0
SUPT4H1	3005.0
MED17	3008.0
CDC26	3013.0
ZNF770	3021.0
GTF2H2	3035.0
AGO2	3046.0
RAD9B	3101.0
GATAD2A	3125.0
HDAC8	3141.0
KMT2D	3244.0
MED4	3271.0
HTT	3299.0
ZNF445	3386.0
PSMB1	3422.0
CREBBP	3460.0
PRDX2	3467.0
AURKA	3503.0
NFYA	3506.0
PSMD5	3507.0
ERCC2	3545.0
ZNF189	3549.0
RNF2	3573.0
PRMT5	3578.0
POLR2G	3581.0
SURF1	3585.0
ZNF205	3595.0
SESN2	3606.0
AKT1	3656.0
FAS	3710.0
ZNF668	3732.0
KRAS	3760.0
ZNF667	3775.0
DPY30	3810.0
TMEM219	3875.0
GTF2H5	3879.0
ZNF354A	3918.0
NELFE	3922.0
PPARGC1A	3934.0
MAPK11	3955.0
JUN	3964.0
ZNF747	3974.0
CSNK2B	3987.0
ZNF333	4038.0
RBX1	4039.0
BIRC5	4082.0
CASP1	4086.0
CBX6	4091.0
PSMB2	4103.0
MDM2	4179.0
COX4I1	4252.0
MAX	4285.0
SKP1	4349.0
ING2	4405.0
UBC	4421.0
KCTD6	4434.0
SEM1	4436.0
CDKN1A	4438.0
MED26	4456.0
SOD2	4458.0
TACO1	4468.0
LAMTOR4	4487.0
COX7B	4554.0
CTSL	4583.0
TBL1XR1	4627.0
SGK1	4642.0
POLR2F	4646.0
PPP2R1A	4669.0
NDRG1	4678.0
PSMD3	4693.0
ZNF552	4708.0
NOTCH1	4733.0
HDAC3	4734.0
ZNF774	4747.0
HDAC5	4761.0
SMARCA4	4789.0
HDAC11	4790.0
CNOT6	4799.0
UBE2S	4810.0
ZNF20	4817.0
DLX6	4879.0
CBX3	4882.0
ARID1A	4896.0
AR	4913.0
DDIT3	4938.0
SMAD2	4939.0
CCNG1	4943.0
ZNF282	5019.0
CDC25C	5024.0
RRAGC	5033.0
H2AC20	5039.0
RFC2	5040.0
GTF2F1	5042.0
ELL	5057.0
CTSK	5077.0
NR2F6	5106.0
ZNF775	5121.0
MAPKAP1	5130.0
COX6A1	5167.0
UBE2C	5168.0
CCNE2	5178.0
TGFB1	5201.0
GPRIN1	5211.0
SNW1	5255.0
NOTCH2	5276.0
CDK7	5292.0
CRADD	5317.0
MED16	5319.0
POLR2L	5362.0
CNOT3	5371.0
PTPN11	5383.0
TWIST2	5405.0
PSMA2	5433.0
MAML1	5447.0
H2BC15	5458.0
H2BC9	5461.0
GTF2F2	5503.0
CBX8	5523.0
USP9X	5542.0
HDAC2	5569.0
PRKAG1	5582.0
RYBP	5586.0
TP53BP2	5594.0
PBRM1	5635.0
AGO1	5660.0
G6PC	5665.0
YWHAZ	5687.0
COX6B1	5755.0
PF4	5777.0
PTPN1	5797.0
RNF111	5821.0
KDM5B	5826.0
PSMD8	5845.0
PRELID1	5864.0
HIPK1	5901.0
ZNF385A	5929.0
THBS1	5946.0
ESRRA	5973.0
PSMA6	5978.0
NCOR1	5979.0
ASH2L	5989.0
PSMD13	5991.0
BAX	5996.0
PSMD7	6017.0
ZNF213	6031.0
HDAC7	6070.0
BID	6075.0
STEAP3	6076.0
H2AZ1	6126.0
IRAK1	6159.0
FOS	6179.0
CSNK2A1	6207.0
EP300	6208.0
PDPK1	6209.0
HIPK2	6215.0
COX5A	6238.0
GPI	6246.0
ANAPC11	6249.0
BRCA1	6273.0
MED25	6290.0
CTDP1	6295.0
PSMD11	6296.0
TIGAR	6306.0
GP1BA	6320.0
COX5B	6328.0
RRAGA	6344.0
RARA	6365.0
NFKB1	6367.0
E2F4	6395.0
YWHAB	6398.0
USP7	6410.0
CSNK2A2	6430.0
CTNNB1	6463.0
CITED2	6467.0
E2F1	6473.0
FOXO4	6493.0
PSMD12	6537.0
TP53INP1	6554.0
NDUFA4	6586.0
SATB2	6611.0
SREBF1	6642.0
TAL1	6644.0
PSMC6	6701.0
COX8A	6712.0
GSK3B	6720.0
PSMF1	6724.0
UBB	6737.0
CCNG2	6752.0
PLK3	6767.0
POLR2J	6769.0
H3C15	6780.5
ZNF230	6798.0
RRM2B	6849.0
MED20	6851.0
UBE2E1	6853.0
JUNB	6889.0
PSMB6	6927.0
ZNF710	6928.0
SUMO1	6973.0
SMARCD2	6976.0
RMI1	6994.0
PRKCB	7056.0
PSMC1	7096.0
PRDX1	7104.0
PSMA7	7174.0
TAF10	7190.0
ZNF267	7214.0
PSMB3	7265.0
PSMD1	7283.0
BCL2L11	7326.0
TAF13	7332.0
PSMA1	7346.0
ELOA	7366.0
VEGFA	7389.0
PSMD2	7470.0
ZFHX3	7472.0
H2BC17	7502.0
CCND3	7510.0
NR1H2	7512.0
RXRA	7513.0
MAPK1	7520.0
H2BC4	7549.0
SERPINE1	7580.0
ELOB	7586.0
RUNX1	7591.0
CITED4	7593.0
MED8	7625.0
ELOC	7637.0
POLR2E	7660.0
RHEB	7675.0
ZNF746	7689.0
LAMTOR3	7692.0
ITGA5	7699.0
LAMTOR2	7704.0
PSMD9	7712.0
MYL9	7719.0
NFYC	7726.0
PPP2CB	7769.0
COX7A2L	7808.0
SMAD6	7853.0
PPM1D	7879.0
PSMD6	7881.0
TOP3A	7914.0
NCOR2	7948.0
NEDD4L	7972.0
TNFRSF10C	7974.0
TBL1X	7984.0
NOTCH3	8004.0
H2AC6	8070.0
H2BC11	8076.0
TAF12	8078.0
KMT5A	8105.0
CEBPB	8108.0
H2BC5	8163.0
PSMB5	8188.0
NRBF2	8203.0
LBR	8224.0
VDR	8258.0
PPM1A	8296.0
TXNRD1	8303.0
PPP2CA	8308.0
CNOT8	8312.0
SP1	8315.0
PSME3	8331.0
LMO2	8335.0
TXN	8414.0
TNFRSF10B	8435.0
SMAD1	8465.0
PSMD4	8498.0
TFDP1	8500.0
PTEN	8516.0
GATA1	8529.0
PSMB7	8535.0
LAMTOR5	8611.0
PRDX5	8612.0
ARID3A	8617.0
LGALS3	8619.0
YWHAH	8621.0
SMARCD3	8637.0
RB1	8649.0
NR6A1	8651.0
JAG1	8661.0
CDK5	8663.0
UBE2D3	8710.0
FOXO3	8729.0
RBPJ	8744.0
H3-3A	8754.0
CDKN2B	8797.0
RRAGD	8850.0
SPI1	8907.0
FKBP5	8936.0
ITGA2B	8942.0
MAML3	8965.0
YWHAE	9009.0
MAP2K6	9010.0
TGFA	9031.0
ANAPC15	9035.0
G6PD	9045.0
TP53I3	9050.0
PINK1	9054.0
HDAC4	9057.0
APAF1	9072.0
MAPK3	9078.0
ZNF697	9092.0
AGO4	9094.0
PHC2	9103.0
CARM1	9122.0
UBE2D1	9125.0
CAT	9137.0
SLC2A3	9144.0
TNFRSF10D	9167.0
H2BC12	9178.0
MAPK14	9219.0
RETN	9241.0
GSR	9256.0
GADD45A	9260.0
BCL6	9299.0
YWHAG	9310.0
BNIP3L	9327.0
H2BC21	9368.0
NLRC4	9406.0
H2AJ	9418.0
PRKACA	9441.0
LAMTOR1	9450.0
NFE2	9490.0
SOCS3	9526.0
CR1	9545.0
PPARG	9571.0

---

COPI-independent Golgi-to-ER retrograde traffic

	133
set	COPI-independent Golgi-to-ER retrograde traffic
setSize	33
pANOVA	2.42e-08
s.dist	0.561
p.adjustANOVA	5e-07

Top enriched genes

GeneID	Gene Rank
PLA2G4A	9234
DCTN2	9158
GALNT2	8896
BICD2	8786
CAPZA2	8521
DCTN4	8385
RAB6A	8223
CAPZA1	8165
CAPZB	8057
RAB18	7893
ACTR10	7652
DYNC1I2	7629
DCTN6	7382
ACTR1A	7088
PAFAH1B2	7026
DYNC1LI1	6992
GALNT1	6518
RAB6B	6149
DCTN3	6080
DYNLL1	6049

Click HERE to show all gene set members

GeneID	Gene Rank
PLA2G4A	9234
DCTN2	9158
GALNT2	8896
BICD2	8786
CAPZA2	8521
DCTN4	8385
RAB6A	8223
CAPZA1	8165
CAPZB	8057
RAB18	7893
ACTR10	7652
DYNC1I2	7629
DCTN6	7382
ACTR1A	7088
PAFAH1B2	7026
DYNC1LI1	6992
GALNT1	6518
RAB6B	6149
DCTN3	6080
DYNLL1	6049
RAB3GAP1	5800
PAFAH1B1	5534
DCTN1	5143
AGPAT3	4625
RAB3GAP2	4478
PAFAH1B3	4373
DYNC1LI2	4253
DYNC1I1	4211
DYNLL2	-4042
DCTN5	-4140
BICD1	-7322
DYNC1H1	-7822
PLA2G6	-12020

---

ER-Phagosome pathway

	328
set	ER-Phagosome pathway
setSize	83
pANOVA	2.45e-08
s.dist	0.354
p.adjustANOVA	5e-07

Top enriched genes

GeneID	Gene Rank
CD36	9486
CD14	9164
TLR2	9069
TLR1	9041
TLR4	8981
TLR6	8931
LY96	8871
SNAP23	8578
PSMB7	8535
PSMD4	8498
PSME3	8331
PSMB5	8188
VAMP3	8121
MYD88	8091
CHUK	7959
PSMD6	7881
PSMD9	7712
PSMD2	7470
PSMA1	7346
PSMD1	7283

Click HERE to show all gene set members

GeneID	Gene Rank
CD36	9486
CD14	9164
TLR2	9069
TLR1	9041
TLR4	8981
TLR6	8931
LY96	8871
SNAP23	8578
PSMB7	8535
PSMD4	8498
PSME3	8331
PSMB5	8188
VAMP3	8121
MYD88	8091
CHUK	7959
PSMD6	7881
PSMD9	7712
PSMD2	7470
PSMA1	7346
PSMD1	7283
PSMB3	7265
PSMA7	7174
BTK	7156
SEC61B	7125
PSMC1	7096
PSMB6	6927
UBB	6737
PSMF1	6724
PSMC6	6701
PSMD12	6537
SEC61A1	6517
CALR	6415
PSMD11	6296
PSMD7	6017
PSMD13	5991
PSMA6	5978
SEC22B	5939
PSMD8	5845
TIRAP	5700
IKBKG	5434
PSMA2	5433
VAMP8	5284
SEC61G	4837
PSMD3	4693
SEM1	4436
UBC	4421
PDIA3	4172
PSMB2	4103
PSMD5	3507
PSMB1	3422
TAPBP	3075
PSMD14	2703
PSMC2	2696
PSMB4	2552
PSMC3	2018
PSMD10	1646
UBA52	1071
HLA-C	1032
HLA-B	658
STX4	626
PSMA4	-538
PSMC5	-948
HLA-G	-2370
HLA-A	-2578
PSMB8	-3080
HLA-H	-3892
HLA-E	-4448
IKBKB	-5290
PSMA3	-5314
PSMB10	-5768
PSME4	-6099
PSMA5	-6154
RPS27A	-6894
B2M	-7019
PSMA8	-7559
PSMC4	-9306
PSME1	-10138
PSME2	-10415
TAP1	-10727
HLA-F	-10771
SEC61A2	-10873
PSMB9	-11362
TAP2	-11828

---

Cellular responses to external stimuli

	169
set	Cellular responses to external stimuli
setSize	506
pANOVA	2.59e-08
s.dist	0.145
p.adjustANOVA	5.2e-07

Top enriched genes

GeneID	Gene Rank
H1-2	9553
GRB10	9508
LAMTOR1	9450
H2AJ	9418
LMNB1	9391
GPX1	9380
PRDX3	9378
H2BC21	9368
NCF4	9365
ATP6V1A	9301
ATP6V0D1	9298
GSR	9256
MAPK14	9219
NCF2	9209
H2BC12	9178
DCTN2	9158
CAT	9137
UBE2D1	9125
ATP6V1D	9118
ATP6V0C	9113

Click HERE to show all gene set members

GeneID	Gene Rank
H1-2	9553.0
GRB10	9508.0
LAMTOR1	9450.0
H2AJ	9418.0
LMNB1	9391.0
GPX1	9380.0
PRDX3	9378.0
H2BC21	9368.0
NCF4	9365.0
ATP6V1A	9301.0
ATP6V0D1	9298.0
GSR	9256.0
MAPK14	9219.0
NCF2	9209.0
H2BC12	9178.0
DCTN2	9158.0
CAT	9137.0
UBE2D1	9125.0
ATP6V1D	9118.0
ATP6V0C	9113.0
PHC2	9103.0
AGO4	9094.0
MAPK3	9078.0
ANAPC15	9035.0
MAP2K6	9010.0
YWHAE	9009.0
ATP6V1B2	9005.0
CYBB	9000.0
PRDX6	8986.0
FKBP5	8936.0
MTF1	8921.0
NUP58	8872.0
ERO1A	8853.0
RRAGD	8850.0
CDKN2B	8797.0
E2F2	8791.0
MAP2K3	8785.0
H3-3A	8754.0
UBE2D3	8710.0
KDM6B	8707.0
ATP6V0B	8701.0
ATP6V0E1	8662.0
RB1	8649.0
ATP6V1C1	8628.0
PRDX5	8612.0
LAMTOR5	8611.0
PSMB7	8535.0
EIF2AK1	8533.0
CAPZA2	8521.0
MAP4K4	8508.0
TFDP1	8500.0
PSMD4	8498.0
P4HB	8452.0
TXN	8414.0
DCTN4	8385.0
BAG4	8384.0
PSME3	8331.0
SP1	8315.0
TXNRD1	8303.0
MAPKAPK3	8255.0
PSMB5	8188.0
HSBP1	8182.0
HSPA1A	8178.0
CAPZA1	8165.0
H2BC5	8163.0
STAT3	8152.0
ATP6V1H	8119.0
CEBPB	8108.0
ATP6V1E1	8107.0
H2BC11	8076.0
ARNT	8074.0
H2AC6	8070.0
CAPZB	8057.0
DNAJB6	8053.0
ETS2	8024.0
NUP214	8011.0
EPAS1	8002.0
CDKN2D	8001.0
AKT1S1	7902.0
PSMD6	7881.0
RPS6KA1	7800.0
MAP3K5	7720.0
PSMD9	7712.0
MT1F	7709.0
LAMTOR2	7704.0
LAMTOR3	7692.0
RHEB	7675.0
CSRP1	7661.0
ACTR10	7652.0
ELOC	7637.0
DYNC1I2	7629.0
H1-0	7598.0
DNAJC7	7594.0
ELOB	7586.0
TXNRD2	7556.0
H2BC4	7549.0
MAPK1	7520.0
H2BC17	7502.0
PSMD2	7470.0
HIGD1A	7465.0
NCF1	7433.0
HIF1A	7404.0
VEGFA	7389.0
DCTN6	7382.0
BMT2	7372.0
PSMA1	7346.0
RPL26L1	7295.0
PSMD1	7283.0
TCIRG1	7266.0
PSMB3	7265.0
HSPA2	7213.0
PSMA7	7174.0
HSPA5	7118.0
PRDX1	7104.0
PSMC1	7096.0
ACTR1A	7088.0
CDKN2C	7019.0
DYNC1LI1	6992.0
VCP	6955.0
CYBA	6952.0
MAP2K4	6948.0
PSMB6	6927.0
UBE2E1	6853.0
EIF2S3	6808.0
H3C15	6780.5
IGFBP7	6753.0
E2F3	6744.0
UBB	6737.0
PSMF1	6724.0
GSK3B	6720.0
PSMC6	6701.0
EGLN1	6700.0
HSPA6	6580.0
PSMD12	6537.0
HSPA1B	6495.0
E2F1	6473.0
CITED2	6467.0
BAG1	6455.0
NFKB1	6367.0
KPTN	6353.0
RRAGA	6344.0
ATF4	6317.0
PSMD11	6296.0
ANAPC11	6249.0
EP300	6208.0
EIF2S2	6203.0
FOS	6179.0
HSF1	6139.0
H2AZ1	6126.0
DCTN3	6080.0
DYNLL1	6049.0
PPP1R15A	6033.0
PSMD7	6017.0
PSMD13	5991.0
PSMA6	5978.0
ATP6V1F	5949.0
PSMD8	5845.0
SEC13	5820.0
ATP6V1E2	5776.0
FNIP1	5671.0
DNAJA2	5663.0
AGO1	5660.0
CEBPG	5551.0
CBX8	5523.0
MT1X	5506.0
RPS9	5496.0
DNAJA1	5489.0
H2BC9	5461.0
H2BC15	5458.0
PSMA2	5433.0
UBN1	5423.0
HSPA4	5416.0
CCNE2	5178.0
UBE2C	5168.0
RAE1	5152.0
DCTN1	5143.0
TERF2IP	5118.0
H2AC20	5039.0
RRAGC	5033.0
DDIT3	4938.0
AR	4913.0
ID1	4819.0
UBE2S	4810.0
TXN2	4728.0
UBE2D2	4721.0
PSMD3	4693.0
TINF2	4667.0
NPRL3	4564.0
NUP50	4544.0
RPL3L	4539.0
LAMTOR4	4487.0
SOD2	4458.0
ATOX1	4439.0
CDKN1A	4438.0
SEM1	4436.0
UBC	4421.0
ERF	4412.0
EIF2S1	4338.0
DYNC1LI2	4253.0
DYNC1I1	4211.0
PTGES3	4180.0
MDM2	4179.0
MAPKAPK2	4176.0
MAPK10	4136.0
PSMB2	4103.0
CBX6	4091.0
RBX1	4039.0
ATP6V1G1	3989.0
JUN	3964.0
MAPK11	3955.0
VHL	3742.0
MINK1	3727.0
FLCN	3639.0
SESN2	3606.0
RNF2	3573.0
PSMD5	3507.0
EGLN2	3497.0
PRDX2	3467.0
CREBBP	3460.0
MIOS	3424.0
PSMB1	3422.0
DEDD2	3360.0
RPS6KA2	3177.0
NUP37	3153.0
NUP98	3124.0
HSPA1L	3102.0
NUDT2	3089.0
H1-4	3026.0
CDC26	3013.0
RPS6KA3	3012.0
VENTX	2938.0
SLC38A9	2861.0
RPS19BP1	2712.0
PSMD14	2703.0
PSMC2	2696.0
CUL2	2559.0
PSMB4	2552.0
HSPA12B	2335.0
NBN	2243.0
CBX4	2237.0
MRPL18	2146.0
RPS27L	2117.0
ATF2	2110.0
PSMC3	2018.0
CAMK2G	1888.0
CXCL8	1797.0
CCNA2	1676.0
MAP2K7	1647.0
PSMD10	1646.0
CCS	1374.0
KAT5	1361.0
HSP90AA1	1348.0
NOX5	1279.0
WDR24	1129.0
NOX4	1116.0
UBA52	1071.0
GPX3	857.0
FKBP4	788.0
NUP62	772.0
ATP7A	647.0
NR3C1	600.0
CCNA1	575.0
MLST8	304.0
GSTP1	197.0
EIF2AK4	144.0
DEPDC5	114.0
RPL36AL	91.0
HMGA1	81.0
RPLP1	-65.0
HIKESHI	-85.0
RPS4Y1	-222.0
RPS24	-282.0
MT1E	-391.0
FAU	-402.0
EGLN3	-450.0
PSMA4	-538.0
CDC27	-659.0
RRAGB	-689.0
RANBP2	-808.0
DNAJA4	-872.0
PSMC5	-948.0
AGO3	-1014.0
RPL15	-1017.0
RPLP0	-1054.0
HSPA13	-1164.0
MDM4	-1218.0
RPL8	-1242.0
H2AZ2	-1266.0
CYCS	-1282.0
MAPK7	-1294.0
ST13	-1304.0
RPS26	-1443.0
RPL28	-1469.0
RPL22L1	-1643.0
HSPA12A	-1743.0
RPS13	-1759.0
RELA	-1807.0
RPL9	-1827.0
RBBP4	-1907.0
RPL7	-2018.0
RPS8	-2138.0
ANAPC16	-2165.0
STIP1	-2170.0
ATP6V1C2	-2222.0
FZR1	-2253.0
HIF3A	-2292.0
HSPA4L	-2347.0
FNIP2	-2391.0
SUZ12	-2444.0
RPL27	-2934.0
RPL39	-3047.0
NUP85	-3077.0
PSMB8	-3080.0
BAG3	-3167.0
IMPACT	-3242.0
RPL23	-3352.0
RPL6	-3382.0
RPL13	-3461.0
TERF1	-3548.0
GPX2	-3560.0
RPL4	-3592.0
RPL29	-3604.0
RPS15	-3698.0
RPL7A	-3699.0
RPL37A	-4004.0
DYNLL2	-4042.0
RING1	-4045.0
RPS21	-4115.0
DCTN5	-4140.0
SIRT1	-4217.0
POT1	-4395.0
RPL31	-4507.0
RPS2	-4509.0
TERF2	-4515.0
TNRC6B	-4558.0
HIF1AN	-4559.0
RPS16	-4570.0
RPL5	-4631.0
RPS28	-4647.0
CBX2	-4693.0
RPS3A	-4702.0
RPL22	-4738.0
BAG5	-4913.0
SOD1	-4927.0
DNAJC2	-5003.0
RPS7	-5016.0
CDK2	-5018.0
RPL18	-5054.0
EEF1A1	-5073.0
ANAPC10	-5074.0
SZT2	-5252.0
ANAPC7	-5259.0
RPL36	-5287.0
CDKN2A	-5302.0
PSMA3	-5314.0
ATF5	-5410.0
RPL17	-5464.0
RPS5	-5478.0
RPS14	-5485.0
SCMH1	-5553.0
TNRC6A	-5567.0
NUP42	-5622.0
DNAJB1	-5625.0
RPS10	-5686.0
RPS15A	-5695.0
PSMB10	-5768.0
RPS3	-5833.0
RPL24	-5882.0
RPL38	-5890.0
TRIB3	-5896.0
SEH1L	-5957.0
RPS4X	-5969.0
RPS12	-5985.0
RPL18A	-6029.0
CDC16	-6037.0
RPL35A	-6080.0
PSME4	-6099.0
RPS6	-6100.0
PSMA5	-6154.0
RLN1	-6210.0
RPSA	-6219.0
RPS17	-6223.0
RPL19	-6242.0
RPS25	-6246.0
RPL11	-6275.0
RPS23	-6279.0
RPL27A	-6321.0
NUP153	-6325.0
CDK6	-6379.0
RPA2	-6397.0
RPL37	-6401.0
RPL21	-6481.0
EP400	-6516.0
RPL14	-6518.0
H2BU1	-6519.0
RPL10	-6562.0
RPL32	-6577.0
RPL26	-6636.0
RPL10A	-6644.0
HSP90AB1	-6702.0
ANAPC4	-6780.0
RPL34	-6807.0
RPL41	-6877.0
RPS27A	-6894.0
RPLP2	-6915.0
RPL30	-6995.0
RPS19	-7037.0
RPL12	-7038.0
TPR	-7100.0
RPS11	-7122.0
MT2A	-7168.0
MAPK9	-7182.0
ANAPC2	-7284.0
POM121C	-7305.0
WTIP	-7336.0
RPL36A	-7442.0
RAD50	-7482.0
BAG2	-7537.0
PSMA8	-7559.0
ACD	-7630.0
RPS18	-7641.0
RPS29	-7794.0
PHC1	-7816.0
DYNC1H1	-7822.0
NUP133	-7839.0
AJUBA	-7848.0
MRE11	-7888.0
RPL13A	-8123.0
PHC3	-8154.0
RPL35	-8239.0
POM121	-8263.0
ASNS	-8299.0
CDKN1B	-8305.0
AAAS	-8337.0
HDAC6	-8348.0
MAPKAPK5	-8452.0
RPL3	-8478.0
HSPA7	-8505.0
EHMT2	-8517.0
NUP54	-8521.0
EHMT1	-8729.0
RPS20	-8922.0
RPL39L	-8982.0
RPA3	-9003.0
WDR59	-9050.0
SH3BP4	-9054.0
GPX7	-9056.0
SESN1	-9083.0
HSPH1	-9227.0
ATP6V1G2	-9275.0
PSMC4	-9306.0
EED	-9417.0
RPL23A	-9477.0
HSPA14	-9589.0
NUP43	-9595.0
MAPK8	-9646.0
RPS27	-9651.0
BMI1	-9787.0
HIRA	-9836.0
ASF1A	-9865.0
EZH2	-9929.0
MTOR	-9948.0
ATF3	-9951.0
HSPA9	-9981.0
PSME1	-10138.0
SERPINH1	-10160.0
NUP35	-10206.0
CCAR2	-10253.0
GCN1	-10284.0
NUP155	-10291.0
NR3C2	-10304.0
NUP160	-10383.0
ATR	-10403.0
PSME2	-10415.0
CABIN1	-10427.0
RPTOR	-10494.0
NUP107	-10570.0
ITFG2	-10682.0
NUP210	-10725.0
ATM	-10839.0
HSPA8	-10913.0
TP53	-10936.0
LIMD1	-10961.0
C12orf66	-10966.0
NUP88	-11046.0
ANAPC5	-11108.0
CDK4	-11138.0
NUP205	-11250.0
ETS1	-11319.0
CDC23	-11349.0
PSMB9	-11362.0
NPRL2	-11435.0
ATP6V0E2	-11475.0
NUP188	-11545.0
TNIK	-11622.0
CCNE1	-11655.0
NUP93	-11700.0
CAMK2D	-11728.0
TNRC6C	-11737.0
ANAPC1	-11870.0
RPA1	-11962.0
MOV10	-11980.0
RBBP7	-12085.0
NDC1	-12113.0
TNFRSF21	-12219.0
TFDP2	-12315.0

---

Cellular response to hypoxia

	168
set	Cellular response to hypoxia
setSize	72
pANOVA	3.91e-08
s.dist	0.374
p.adjustANOVA	7.65e-07

Top enriched genes

GeneID	Gene Rank
UBE2D1	9125
UBE2D3	8710
PSMB7	8535
PSMD4	8498
PSME3	8331
PSMB5	8188
ARNT	8074
EPAS1	8002
PSMD6	7881
PSMD9	7712
ELOC	7637
ELOB	7586
PSMD2	7470
HIGD1A	7465
HIF1A	7404
VEGFA	7389
PSMA1	7346
PSMD1	7283
PSMB3	7265
PSMA7	7174

Click HERE to show all gene set members

GeneID	Gene Rank
UBE2D1	9125
UBE2D3	8710
PSMB7	8535
PSMD4	8498
PSME3	8331
PSMB5	8188
ARNT	8074
EPAS1	8002
PSMD6	7881
PSMD9	7712
ELOC	7637
ELOB	7586
PSMD2	7470
HIGD1A	7465
HIF1A	7404
VEGFA	7389
PSMA1	7346
PSMD1	7283
PSMB3	7265
PSMA7	7174
PSMC1	7096
PSMB6	6927
UBB	6737
PSMF1	6724
PSMC6	6701
EGLN1	6700
PSMD12	6537
CITED2	6467
PSMD11	6296
EP300	6208
PSMD7	6017
PSMD13	5991
PSMA6	5978
PSMD8	5845
PSMA2	5433
UBE2D2	4721
PSMD3	4693
SEM1	4436
UBC	4421
PSMB2	4103
RBX1	4039
VHL	3742
PSMD5	3507
EGLN2	3497
CREBBP	3460
PSMB1	3422
PSMD14	2703
PSMC2	2696
CUL2	2559
PSMB4	2552
PSMC3	2018
PSMD10	1646
UBA52	1071
EGLN3	-450
PSMA4	-538
PSMC5	-948
HIF3A	-2292
PSMB8	-3080
HIF1AN	-4559
PSMA3	-5314
PSMB10	-5768
PSME4	-6099
PSMA5	-6154
RPS27A	-6894
WTIP	-7336
PSMA8	-7559
AJUBA	-7848
PSMC4	-9306
PSME1	-10138
PSME2	-10415
LIMD1	-10961
PSMB9	-11362

---

Detoxification of Reactive Oxygen Species

	279
set	Detoxification of Reactive Oxygen Species
setSize	32
pANOVA	3.93e-08
s.dist	0.561
p.adjustANOVA	7.65e-07

Top enriched genes

GeneID	Gene Rank
GPX1	9380
PRDX3	9378
NCF4	9365
GSR	9256
NCF2	9209
CAT	9137
CYBB	9000
PRDX6	8986
ERO1A	8853
PRDX5	8612
P4HB	8452
TXN	8414
TXNRD1	8303
TXNRD2	7556
NCF1	7433
PRDX1	7104
CYBA	6952
TXN2	4728
SOD2	4458
ATOX1	4439

Click HERE to show all gene set members

GeneID	Gene Rank
GPX1	9380
PRDX3	9378
NCF4	9365
GSR	9256
NCF2	9209
CAT	9137
CYBB	9000
PRDX6	8986
ERO1A	8853
PRDX5	8612
P4HB	8452
TXN	8414
TXNRD1	8303
TXNRD2	7556
NCF1	7433
PRDX1	7104
CYBA	6952
TXN2	4728
SOD2	4458
ATOX1	4439
PRDX2	3467
NUDT2	3089
CCS	1374
NOX5	1279
NOX4	1116
GPX3	857
ATP7A	647
GSTP1	197
CYCS	-1282
GPX2	-3560
SOD1	-4927
GPX7	-9056

---

Signaling by Nuclear Receptors

	1122
set	Signaling by Nuclear Receptors
setSize	217
pANOVA	4.03e-08
s.dist	0.216
p.adjustANOVA	7.75e-07

Top enriched genes

GeneID	Gene Rank
CTSD	9475
GNG10	9436
H2AJ	9418
MMP9	9370
H2BC21	9368
H2BC12	9178
CARM1	9122
AGO4	9094
MAPK3	9078
ALDH1A2	9044
TGFA	9031
FKBP5	8936
GNG5	8866
H3-3A	8754
FOXO3	8729
TLE3	8679
ZDHHC7	8609
SP1	8315
GNB1	8278
EGF	8267

Click HERE to show all gene set members

GeneID	Gene Rank
CTSD	9475.0
GNG10	9436.0
H2AJ	9418.0
MMP9	9370.0
H2BC21	9368.0
H2BC12	9178.0
CARM1	9122.0
AGO4	9094.0
MAPK3	9078.0
ALDH1A2	9044.0
TGFA	9031.0
FKBP5	8936.0
GNG5	8866.0
H3-3A	8754.0
FOXO3	8729.0
TLE3	8679.0
ZDHHC7	8609.0
SP1	8315.0
GNB1	8278.0
EGF	8267.0
GNB2	8234.0
H2BC5	8163.0
GNAI2	8094.0
H2BC11	8076.0
H2AC6	8070.0
KDM4B	8038.0
GNAI3	8027.0
TBL1X	7984.0
NCOR2	7948.0
TFF3	7871.0
SPHK1	7724.0
POLR2E	7660.0
RUNX1	7591.0
H2BC4	7549.0
MAPK1	7520.0
RXRA	7513.0
NR1H2	7512.0
H2BC17	7502.0
PLTP	7453.0
DLD	7253.0
GTF2A2	7207.0
SRF	7205.0
GNB4	7138.0
H3C15	6780.5
POLR2J	6769.0
SREBF1	6642.0
GNG11	6612.0
USF2	6541.0
RARA	6365.0
RDH11	6355.0
EEPD1	6343.0
PDPK1	6209.0
EP300	6208.0
FOS	6179.0
H2AZ1	6126.0
FABP5	6123.0
ABCA1	6066.0
IGF1R	6032.0
NCOR1	5979.0
PDK4	5854.0
AGO1	5660.0
GTF2F2	5503.0
AREG	5494.0
H2BC9	5461.0
H2BC15	5458.0
NRAS	5411.0
POLR2L	5362.0
S1PR3	5343.0
STAG2	5339.0
CPT1A	5153.0
PIK3R2	5051.0
GTF2F1	5042.0
H2AC20	5039.0
KDM1B	4958.0
USF1	4893.0
HBEGF	4878.0
PPID	4758.0
HDAC3	4734.0
PIK3CA	4697.0
POLR2F	4646.0
TBL1XR1	4627.0
NRIP1	4616.0
CAV2	4602.0
NCOA1	4563.0
PTK2	4506.0
KCTD6	4434.0
PDHX	4344.0
GNG8	4339.0
PDHB	4292.0
PDK1	4269.0
PTGES3	4180.0
SHC1	4173.0
SCD	4108.0
JUN	3964.0
MMP7	3952.0
DHRS4	3835.0
KRAS	3760.0
STRN	3758.0
AKT1	3656.0
POLR2G	3581.0
NCOA3	3563.0
CREBBP	3460.0
GNAI1	3364.0
PDK3	3304.0
ZNF217	3266.0
ABCG8	3112.0
DHRS9	3076.0
AGO2	3046.0
CETP	2908.0
GTF2A1	2744.0
EPGN	2579.0
MYC	2367.0
CBFB	2152.0
ATF2	2110.0
EREG	1906.0
CAV1	1856.0
RAD21	1719.0
POU2F1	1611.0
JUND	1561.0
POLR2C	1531.0
FOSB	1432.0
KAT5	1361.0
HSP90AA1	1348.0
NCOA2	1109.0
ELK1	1040.0
APOD	1010.0
GNG3	894.0
FKBP4	788.0
SMC1A	659.0
RDH5	602.0
MYB	555.0
YY1	529.0
GNB5	467.0
HDAC1	394.0
AKT2	345.0
POLR2I	316.0
APOE	103.0
KDM4A	38.0
CHD1	-6.0
FASN	-702.0
GPS2	-914.0
AGO3	-1014.0
XPO1	-1199.0
H2AZ2	-1266.0
CREB1	-1382.0
CRABP2	-1473.0
NOS3	-1718.0
POLR2K	-1792.0
SMC3	-1982.0
CALM1	-2048.0
GNG4	-2175.0
KAT2B	-2393.0
POLR2B	-2536.0
GNB3	-2776.0
POLR2H	-2817.0
POLR2A	-3105.0
RXRB	-3221.0
HRAS	-3335.0
NR1H3	-3418.0
PLIN1	-3507.0
DLAT	-3566.0
UHMK1	-3901.0
KANK1	-3909.0
CDK9	-3988.0
MYLIP	-4005.0
POLR2D	-4058.0
MED1	-4082.0
RDH10	-4447.0
BCL2	-4480.0
PDHA1	-4484.0
TNRC6B	-4558.0
CPT1B	-4560.0
RARG	-4816.0
GNG7	-5049.0
TNRC6A	-5567.0
PPARD	-6092.0
ZDHHC21	-6207.0
STAG1	-6429.0
H2BU1	-6519.0
HSP90AB1	-6702.0
KPNA2	-6845.0
CCND1	-6847.0
GREB1	-6981.0
ALDH8A1	-7195.0
CXXC5	-7252.0
PPP5C	-7588.0
GNG2	-7809.0
ABCG1	-8065.0
PDK2	-8114.0
CDKN1B	-8305.0
RDH16	-8616.0
PRMT1	-8894.0
SRC	-9011.0
TBP	-9220.0
ESR1	-9230.0
ESR2	-9236.0
KDM1A	-9476.0
CCNT1	-9570.0
PIK3R1	-9725.0
DDX5	-9806.0
GPAM	-9993.0
RDH14	-10270.0
AXIN1	-10310.0
EBAG9	-10325.0
RDH13	-10697.0
PRKCZ	-11508.0
ALDH1A1	-11523.0
TNRC6C	-11737.0
AKT3	-11804.0
KDM3A	-11950.0
MOV10	-11980.0
PIK3R3	-12037.0
GNGT2	-12070.0
DHRS3	-12082.0
AKR1C3	-12115.0
GATA3	-12140.0
ARL4C	-12246.0

---

Cargo recognition for clathrin-mediated endocytosis

	148
set	Cargo recognition for clathrin-mediated endocytosis
setSize	90
pANOVA	4.62e-08
s.dist	0.333
p.adjustANOVA	8.64e-07

Top enriched genes

GeneID	Gene Rank
VAMP7	9549
GRB2	9320
AGFG1	9261
ITSN1	9186
CLTC	9056
PICALM	9052
TGFA	9031
CLTCL1	8939
AP2M1	8673
TGOLN2	8647
ARRB2	8517
CLTA	8402
REPS2	8273
EGF	8267
DAB2	8259
VAMP3	8121
TOR1A	8085
AP2S1	8080
EPN1	8026
FCHO2	7762

Click HERE to show all gene set members

GeneID	Gene Rank
VAMP7	9549
GRB2	9320
AGFG1	9261
ITSN1	9186
CLTC	9056
PICALM	9052
TGFA	9031
CLTCL1	8939
AP2M1	8673
TGOLN2	8647
ARRB2	8517
CLTA	8402
REPS2	8273
EGF	8267
DAB2	8259
VAMP3	8121
TOR1A	8085
AP2S1	8080
EPN1	8026
FCHO2	7762
SH3GL1	7733
CBL	7599
AP2A2	7360
IGF2R	7270
UBB	6737
COPS7A	6649
AP2A1	6628
NEDD8	6597
GRK3	6469
LDLR	6329
SH3KBP1	6227
CLTB	6195
STAM2	6183
COPS2	6147
GRK2	6141
COPS3	6040
UBQLN2	6009
AREG	5494
VAMP8	5284
UBQLN1	5164
SYT1	5162
ITSN2	5108
SCARB2	4979
HBEGF	4878
HGS	4570
UBC	4421
COPS5	4415
EPS15	4189
STON2	3698
EPS15L1	3688
NECAP2	3428
KIAA0319	3373
VAMP4	3236
CFTR	2738
STON1	2624
EPGN	2579
NECAP1	2247
ARRB1	2098
EREG	1906
COPS4	1865
COPS6	1663
TFRC	1578
STAM	1299
LRP2	1222
TF	1172
UBA52	1071
SYT2	451
AVPR2	306
TOR1B	-1930
FCHO1	-2036
AP2B1	-2748
EPN2	-3979
GPS1	-4577
CD4	-5320
SYT11	-6617
RPS27A	-6894
REPS1	-7232
M6PR	-8665
COPS8	-8868
LDLRAP1	-8898
AAK1	-9323
COPS7B	-9938
IL7R	-10324
DVL2	-10753
CD3D	-11094
CD3G	-11409
VAMP2	-11692
FZD4	-11733
SLC2A8	-11810
ADRB2	-11879

---

RUNX1 regulates transcription of genes involved in differentiation of HSCs

	928
set	RUNX1 regulates transcription of genes involved in differentiation of HSCs
setSize	83
pANOVA	4.63e-08
s.dist	0.347
p.adjustANOVA	8.64e-07

Top enriched genes

GeneID	Gene Rank
H2AJ	9418
H2BC21	9368
H2BC12	9178
SPI1	8907
H3-3A	8754
PSMB7	8535
GATA1	8529
PSMD4	8498
LMO2	8335
PSME3	8331
PSMB5	8188
H2BC5	8163
H2BC11	8076
H2AC6	8070
PSMD6	7881
PSMD9	7712
RUNX1	7591
H2BC4	7549
H2BC17	7502
PSMD2	7470

Click HERE to show all gene set members

GeneID	Gene Rank
H2AJ	9418.0
H2BC21	9368.0
H2BC12	9178.0
SPI1	8907.0
H3-3A	8754.0
PSMB7	8535.0
GATA1	8529.0
PSMD4	8498.0
LMO2	8335.0
PSME3	8331.0
PSMB5	8188.0
H2BC5	8163.0
H2BC11	8076.0
H2AC6	8070.0
PSMD6	7881.0
PSMD9	7712.0
RUNX1	7591.0
H2BC4	7549.0
H2BC17	7502.0
PSMD2	7470.0
PSMA1	7346.0
PSMD1	7283.0
PSMB3	7265.0
PSMA7	7174.0
PSMC1	7096.0
PSMB6	6927.0
H3C15	6780.5
UBB	6737.0
PSMF1	6724.0
PSMC6	6701.0
TAL1	6644.0
PSMD12	6537.0
PSMD11	6296.0
H2AZ1	6126.0
PSMD7	6017.0
PSMD13	5991.0
PSMA6	5978.0
PSMD8	5845.0
H2BC9	5461.0
H2BC15	5458.0
PSMA2	5433.0
CDK7	5292.0
H2AC20	5039.0
PSMD3	4693.0
SEM1	4436.0
UBC	4421.0
PSMB2	4103.0
PSMD5	3507.0
PSMB1	3422.0
PSMD14	2703.0
PSMC2	2696.0
PSMB4	2552.0
CBFB	2152.0
PSMC3	2018.0
PSMD10	1646.0
ITCH	1394.0
UBA52	1071.0
CCNH	783.0
MYB	555.0
ABL1	229.0
PSMA4	-538.0
PSMC5	-948.0
H2AZ2	-1266.0
TCF12	-1268.0
PSMB8	-3080.0
TP73	-4805.0
PSMA3	-5314.0
PSMB10	-5768.0
PSME4	-6099.0
PSMA5	-6154.0
H2BU1	-6519.0
TCF3	-6757.0
RPS27A	-6894.0
PSMA8	-7559.0
MNAT1	-8852.0
GATA2	-9305.0
PSMC4	-9306.0
LDB1	-9701.0
PSME1	-10138.0
PSME2	-10415.0
KMT2A	-10672.0
PSMB9	-11362.0
GATA3	-12140.0

---

Infectious disease

	525
set	Infectious disease
setSize	724
pANOVA	4.92e-08
s.dist	0.119
p.adjustANOVA	9.06e-07

Top enriched genes

GeneID	Gene Rank
WASF1	9568
HRH2	9509
GGT1	9495
CD163	9493
ADM	9454
PRKACA	9441
GNG10	9436
GPR27	9426
FCGR1A	9397
IL10	9385
H2BC21	9368
IMPDH1	9364
AP1S1	9338
GRB2	9320
ARPC1B	9303
GPR84	9292
ST6GALNAC3	9271
CYFIP1	9270
MAPK14	9219
GUCY2C	9182

Click HERE to show all gene set members

GeneID	Gene Rank
WASF1	9568.0
HRH2	9509.0
GGT1	9495.0
CD163	9493.0
ADM	9454.0
PRKACA	9441.0
GNG10	9436.0
GPR27	9426.0
FCGR1A	9397.0
IL10	9385.0
H2BC21	9368.0
IMPDH1	9364.0
AP1S1	9338.0
GRB2	9320.0
ARPC1B	9303.0
GPR84	9292.0
ST6GALNAC3	9271.0
CYFIP1	9270.0
MAPK14	9219.0
GUCY2C	9182.0
H2BC12	9178.0
FURIN	9162.0
ADCY3	9101.0
SYK	9087.0
ARF1	9083.0
MAPK3	9078.0
TLR2	9069.0
FKBP1A	9066.0
ACTB	9060.0
CLTC	9056.0
IL1R1	9030.0
MAP2K6	9010.0
HCK	8992.0
MAP2K1	8960.0
CRK	8941.0
MYO10	8933.0
ARPC1A	8923.0
ENO1	8877.0
NUP58	8872.0
GNG5	8866.0
CHMP2A	8863.0
FCGR2A	8858.0
CHMP4B	8830.0
CEBPD	8826.0
NLRP3	8813.0
MAP2K3	8785.0
ST3GAL2	8782.0
UBAP1	8779.0
RAB7A	8775.0
AP1B1	8741.0
PYCARD	8734.0
RAC1	8720.0
PGK1	8681.0
AP2M1	8673.0
ACTG1	8671.0
ARPC5	8653.0
RB1	8649.0
PRKAR1A	8616.0
WAS	8596.0
MEFV	8576.0
PSMB7	8535.0
ADORA2B	8515.0
PSMD4	8498.0
DNAJC3	8468.0
TXN	8414.0
CLTA	8402.0
FGR	8397.0
WASF2	8373.0
ENTPD1	8372.0
CHMP3	8339.0
JAK3	8337.0
PSME3	8331.0
ARPC3	8309.0
TXNRD1	8303.0
GNB1	8278.0
COMT	8260.0
TRIM27	8257.0
GNB2	8234.0
IL6R	8229.0
PAK2	8226.0
PSMB5	8188.0
HSPA1A	8178.0
H2BC5	8163.0
ATP6V1H	8119.0
MAP1LC3B	8099.0
GNAI2	8094.0
AP2S1	8080.0
TAF12	8078.0
H2BC11	8076.0
H2AC6	8070.0
C3AR1	8067.0
PRKAR1B	8040.0
GNAI3	8027.0
VAV1	8021.0
GNAS	8019.0
NUP214	8011.0
TBL1X	7984.0
ADAM17	7980.0
VPS37C	7973.0
NEDD4L	7972.0
NCOR2	7948.0
PSTPIP1	7930.0
ACTR3	7888.0
PSMD6	7881.0
TSG101	7856.0
ACTR2	7827.0
GSK3A	7811.0
P2RX4	7740.0
SH3GL1	7733.0
LYN	7728.0
PSMD9	7712.0
VPS25	7696.0
H2AC11	7674.0
POLR2E	7660.0
ELOC	7637.0
DOCK2	7631.0
DYNC1I2	7629.0
HNRNPK	7619.0
ARPC4	7605.0
CBL	7599.0
ELOB	7586.0
NCKAP1	7562.0
H2BC4	7549.0
CDC42	7539.0
MAPK1	7520.0
NCKAP1L	7516.0
H2BC17	7502.0
PSMD2	7470.0
ARPC2	7449.0
ROCK1	7445.0
ANTXR2	7435.0
MVB12A	7425.0
DOCK1	7413.0
IL18	7395.0
VEGFA	7389.0
ELOA	7366.0
AP2A2	7360.0
IL1RAP	7349.0
PSMA1	7346.0
TAF13	7332.0
RPL26L1	7295.0
PSMD1	7283.0
PSMB3	7265.0
RXFP2	7217.0
GTF2A2	7207.0
TYK2	7192.0
TAF10	7190.0
PSMA7	7174.0
RAB5A	7166.0
BTK	7156.0
ABI1	7154.0
GNB4	7138.0
PSMC1	7096.0
BRK1	7085.0
DYNC1LI1	6992.0
SUMO1	6973.0
VCP	6955.0
CYBA	6952.0
MAP2K4	6948.0
PSMB6	6927.0
WASF3	6915.0
MAP2K2	6906.0
ST6GALNAC2	6828.0
PRKAR2B	6824.0
XRCC4	6793.0
AP1M1	6788.0
H3C15	6780.5
MYH9	6772.0
POLR2J	6769.0
UBB	6737.0
PSMF1	6724.0
GSK3B	6720.0
PSMC6	6701.0
MYO5A	6685.0
INSL3	6681.0
AP2A1	6628.0
GNG11	6612.0
PDCD6IP	6585.0
VPS37A	6560.0
PSMD12	6537.0
GALNT1	6518.0
MYO9B	6481.0
AHCYL1	6475.0
CTNNB1	6463.0
RLN3	6445.0
BECN1	6423.0
CALR	6415.0
H2BC18	6400.0
NFKB1	6367.0
SLC25A6	6340.0
ELMO1	6324.0
PSMD11	6296.0
CTDP1	6295.0
PRKAR2A	6265.0
VTA1	6232.0
SH3KBP1	6227.0
MGAT1	6190.0
STAM2	6183.0
LTF	6182.0
ROCK2	6151.0
DYNLL1	6049.0
PSMD7	6017.0
CD9	6004.0
PSMD13	5991.0
SNF8	5990.0
NCOR1	5979.0
PSMA6	5978.0
BRD4	5959.0
ADM2	5935.0
ST3GAL4	5930.0
ITPR2	5919.0
GTF2E2	5856.0
PSMD8	5845.0
CHMP1A	5834.0
SEC13	5820.0
WIPF2	5769.0
DVL3	5734.0
CHMP2B	5713.0
CHMP6	5590.0
HDAC2	5569.0
CANX	5526.0
GTF2F2	5503.0
RPS9	5496.0
H2BC9	5461.0
H2BC15	5458.0
XRCC5	5452.0
PSMA2	5433.0
LIG4	5391.0
POLR2L	5362.0
PRKCSH	5300.0
CDK7	5292.0
VPS4B	5279.0
MVB12B	5251.0
GRSF1	5232.0
ADCY4	5226.0
CTSG	5224.0
CORO1A	5206.0
TGFB1	5201.0
CALCRL	5199.0
SYT1	5162.0
RAE1	5152.0
PLCG2	5103.0
KPNA4	5074.0
ELL	5057.0
GTF2F1	5042.0
H2AC20	5039.0
VAV3	4974.0
CHMP5	4954.0
HBEGF	4878.0
IL1B	4830.0
CBX1	4763.0
HDAC3	4734.0
PSMD3	4693.0
POLR2F	4646.0
TBL1XR1	4627.0
CTSL	4583.0
HGS	4570.0
NUP50	4544.0
RPL3L	4539.0
ELMO2	4507.0
PTK2	4506.0
SEM1	4436.0
UBC	4421.0
NMT1	4400.0
SKP1	4349.0
GNG8	4339.0
PARP4	4298.0
DYNC1LI2	4253.0
VPS28	4247.0
DYNC1I1	4211.0
RHBDF2	4205.0
EPS15	4189.0
PSMB2	4103.0
CASP1	4086.0
AP1G1	4052.0
RBX1	4039.0
PDZD3	4007.0
JUN	3964.0
VPS37B	3933.0
NELFE	3922.0
GTF2H5	3879.0
VHL	3742.0
GTF2B	3599.0
POLR2G	3581.0
ERCC2	3545.0
PSMD5	3507.0
PSMB1	3422.0
P2RX7	3420.0
GNAI1	3364.0
MYO1C	3351.0
ADORA2A	3227.0
MRC1	3187.0
TBK1	3159.0
NUP37	3153.0
NUP98	3124.0
GTF2H2	3035.0
RNGTT	3030.0
SUPT4H1	3005.0
POMC	2971.0
CCNK	2936.0
GNAZ	2927.0
ATP1A1	2849.0
RAMP3	2787.0
GTF2A1	2744.0
PSMD14	2703.0
PSMC2	2696.0
JAK2	2599.0
PSMB4	2552.0
KPNB1	2491.0
CHMP4A	2480.0
GTF2E1	2363.0
SFPQ	2294.0
RPS27L	2117.0
TSHR	2057.0
PSMC3	2018.0
TAF7	1986.0
IRS1	1806.0
AP1M2	1740.0
RCC1	1712.0
MAP2K7	1647.0
PSMD10	1646.0
PIK3C3	1626.0
SUGT1	1576.0
POLR2C	1531.0
PTGER2	1451.0
HSP90AA1	1348.0
KPNA1	1320.0
STAM	1299.0
TAF9	1249.0
UBA52	1071.0
ELK1	1040.0
KPNA3	958.0
GNG3	894.0
SLC25A5	892.0
CUL5	847.0
CCNH	783.0
VPS4A	776.0
NUP62	772.0
ZCRB1	691.0
IGHV1-2	679.0
NR3C1	600.0
WIPF1	581.0
ST3GAL3	485.0
GNB5	467.0
SYT2	451.0
NELFB	385.0
NCKIPSD	320.0
POLR2I	316.0
AVPR2	306.0
EEF2	289.0
WASL	283.0
ABL1	229.0
IGHV2-5	174.0
ADCY9	146.0
IGHV3-53	122.0
RPL36AL	91.0
HMGA1	81.0
DVL1	61.0
IGLC3	-37.0
ITGB1	-50.0
RPLP1	-65.0
CXCR4	-125.0
IGKV1-39	-173.0
BAIAP2	-179.0
RPS4Y1	-222.0
RPS24	-282.0
IGKV5-2	-357.0
FAU	-402.0
IGLV5-45	-419.0
IGHV3-7	-437.0
IGKV3-11	-446.0
PABPN1	-526.0
PSMA4	-538.0
IGHV3-48	-583.0
TLR7	-655.0
GGT5	-679.0
GPR83	-685.0
IGLV2-8	-740.0
UBE2I	-746.0
RANBP2	-808.0
IGHV1-46	-823.0
ST6GALNAC4	-827.0
NFKB2	-865.0
GPS2	-914.0
PSMC5	-948.0
TCEA1	-951.0
IGKV1-5	-984.0
IGKV1-16	-990.0
GANAB	-1004.0
RPL15	-1017.0
IGHV3-23	-1042.0
RPLP0	-1054.0
IGKV1D-39	-1172.0
XPO1	-1199.0
RPL8	-1242.0
IGKV2D-28	-1291.0
IGLV7-46	-1341.0
CREB1	-1382.0
IGLV10-54	-1414.0
IGHV3-13	-1436.0
RPS26	-1443.0
RPL28	-1469.0
IGLV2-18	-1472.0
IGKV1-33	-1613.0
RPL22L1	-1643.0
IGLV1-36	-1670.0
SV2B	-1692.0
IGKV2-30	-1725.0
TAF4	-1726.0
ADCY6	-1746.0
RPS13	-1759.0
IGLV4-69	-1768.0
POLR2K	-1792.0
RELA	-1807.0
IGHV1-69	-1811.0
TAF3	-1820.0
RPL9	-1827.0
RBBP4	-1907.0
IGHV4-59	-1969.0
VPS33B	-2000.0
IGLV3-19	-2016.0
RPL7	-2018.0
IGKV3-15	-2034.0
IGHV3-11	-2041.0
CALM1	-2048.0
IGHV4-34	-2080.0
RPS8	-2138.0
GNG4	-2175.0
IGHV3-30	-2221.0
GTF2H3	-2247.0
AP1S2	-2330.0
SUZ12	-2444.0
HTR7	-2465.0
POLR2B	-2536.0
HLA-A	-2578.0
IGLV2-23	-2597.0
TAF9B	-2602.0
IGKV4-1	-2625.0
AP2B1	-2748.0
DPEP2	-2760.0
PLK2	-2772.0
GNB3	-2776.0
IGLV2-11	-2782.0
IGKV1-17	-2799.0
POLR2H	-2817.0
IGKV3-20	-2824.0
ADCY2	-2874.0
IGLV6-57	-2876.0
TAF11	-2897.0
GTF2H4	-2906.0
GTF2H1	-2929.0
RPL27	-2934.0
STX1B	-2970.0
DPEP3	-2980.0
IGHV3-33	-2989.0
SV2C	-3038.0
RPL39	-3047.0
MOGS	-3075.0
IGLV1-44	-3076.0
NUP85	-3077.0
PSMB8	-3080.0
POLR2A	-3105.0
IGHV2-70	-3195.0
ADCY7	-3307.0
RPL23	-3352.0
RPL6	-3382.0
IGHG3	-3394.0
RPL13	-3461.0
RPL4	-3592.0
RPL29	-3604.0
RPS15	-3698.0
RPL7A	-3699.0
IGHV4-39	-3735.0
NELFA	-3858.0
CDK9	-3988.0
RPL37A	-4004.0
IGKV3D-20	-4012.0
PIK3R4	-4040.0
DYNLL2	-4042.0
POLR2D	-4058.0
STX1A	-4061.0
VAV2	-4073.0
IGLV3-1	-4093.0
IGLV7-43	-4100.0
IGLV1-40	-4105.0
RPS21	-4115.0
IGKC	-4212.0
IGLV3-25	-4239.0
HTR6	-4345.0
IGLV1-51	-4413.0
IGLV3-21	-4455.0
TAF5	-4458.0
XRCC6	-4475.0
RPL31	-4507.0
RPS2	-4509.0
RPS16	-4570.0
RPL5	-4631.0
RPS28	-4647.0
PARP9	-4658.0
RPS3A	-4702.0
RPL22	-4738.0
IGLC7	-4779.0
BANF1	-4839.0
TRIM28	-4905.0
BTRC	-4932.0
NT5E	-4939.0
PARP6	-4956.0
CRHR2	-4975.0
RPS7	-5016.0
GNG7	-5049.0
RPL18	-5054.0
CCNT2	-5173.0
IGKV1-12	-5223.0
RPL36	-5287.0
PSMA3	-5314.0
CD4	-5320.0
IGLC2	-5370.0
IGLV8-61	-5395.0
RPL17	-5464.0
RPS5	-5478.0
RPS14	-5485.0
NOXA1	-5532.0
IGLC1	-5548.0
AP1S3	-5592.0
NUP42	-5622.0
IGHG1	-5669.0
RPS10	-5686.0
RPS15A	-5695.0
PSMB10	-5768.0
IGKV2-28	-5778.0
IGLV1-47	-5810.0
RPS3	-5833.0
NCBP1	-5866.0
RPL24	-5882.0
RPL38	-5890.0
TLR9	-5909.0
IGLV3-27	-5935.0
SEH1L	-5957.0
RPS4X	-5969.0
RPS12	-5985.0
TAF2	-5999.0
RPL18A	-6029.0
DUT	-6053.0
RPL35A	-6080.0
PSME4	-6099.0
RPS6	-6100.0
VIPR1	-6107.0
PSMA5	-6154.0
RPSA	-6219.0
RPS17	-6223.0
CRBN	-6236.0
RPL19	-6242.0
RPS25	-6246.0
ENTPD5	-6256.0
RPL11	-6275.0
RPS23	-6279.0
NELFCD	-6291.0
RPL27A	-6321.0
NUP153	-6325.0
RPL37	-6401.0
RPL21	-6481.0
FZD7	-6496.0
RPL14	-6518.0
H2BU1	-6519.0
TAF15	-6541.0
RPL10	-6562.0
RPL32	-6577.0
RPL26	-6636.0
RPL10A	-6644.0
DUSP16	-6652.0
GPR15	-6674.0
HSP90AB1	-6702.0
IGHG4	-6718.0
SUPT5H	-6744.0
RPL34	-6807.0
KPNA2	-6845.0
RAN	-6874.0
RPL41	-6877.0
RPS27A	-6894.0
PPIA	-6900.0
RPLP2	-6915.0
VPS36	-6942.0
PDCD1	-6963.0
RPL30	-6995.0
B2M	-7019.0
RPS19	-7037.0
RPL12	-7038.0
TUBB	-7078.0
IGHG2	-7087.0
TPR	-7100.0
RPS11	-7122.0
GPBAR1	-7268.0
POM121C	-7305.0
TAF6	-7402.0
RPL36A	-7442.0
ST3GAL1	-7452.0
IGLV3-12	-7472.0
ITPR1	-7553.0
PSMA8	-7559.0
CD8B	-7599.0
RPS18	-7641.0
VAMP1	-7646.0
SIGMAR1	-7681.0
ERCC3	-7721.0
RPS29	-7794.0
CYSLTR1	-7801.0
ADRB1	-7803.0
GNG2	-7809.0
DYNC1H1	-7822.0
NUP133	-7839.0
TAF4B	-7865.0
RLN2	-7910.0
RPL13A	-8123.0
RPL35	-8239.0
POM121	-8263.0
RAMP1	-8282.0
ADCY5	-8315.0
CHMP7	-8325.0
AAAS	-8337.0
PACS1	-8402.0
PARP10	-8407.0
IGLV2-14	-8416.0
RPL3	-8478.0
CTNND1	-8519.0
NUP54	-8521.0
PARP8	-8523.0
TAF1	-8536.0
CBLL1	-8668.0
MNAT1	-8852.0
PML	-8888.0
RPS20	-8922.0
CCR5	-8977.0
RPL39L	-8982.0
SRC	-9011.0
CYSLTR2	-9085.0
UVRAG	-9200.0
TBP	-9220.0
S1PR1	-9239.0
PSMC4	-9306.0
PTGIR	-9321.0
EIF2AK2	-9395.0
EED	-9417.0
RPL23A	-9477.0
CCNT1	-9570.0
NUP43	-9595.0
NPM1	-9596.0
IMPDH2	-9608.0
CPSF4	-9615.0
NCBP2	-9624.0
MAPK8	-9646.0
RPS27	-9651.0
TXNIP	-9792.0
PSIP1	-9800.0
DDX5	-9806.0
RANBP1	-9854.0
CD28	-9858.0
EZH2	-9929.0
ITPR3	-9955.0
GPR150	-10012.0
PSME1	-10138.0
NUP35	-10206.0
NUP155	-10291.0
NUP160	-10383.0
CYFIP2	-10387.0
PSME2	-10415.0
LIG1	-10471.0
PLCG1	-10473.0
PRKX	-10527.0
NUP107	-10570.0
DAXX	-10582.0
IPO5	-10677.0
GPR25	-10714.0
NUP210	-10725.0
SV2A	-10729.0
FEN1	-10740.0
DVL2	-10753.0
MC1R	-10836.0
ABI2	-10893.0
P2RY11	-10982.0
ITGA4	-11003.0
NUP88	-11046.0
JAK1	-11075.0
RIPK1	-11184.0
RNMT	-11210.0
SSRP1	-11213.0
NUP205	-11250.0
PSMB9	-11362.0
DBP	-11405.0
CD3G	-11409.0
SUPT16H	-11458.0
NCK1	-11488.0
LCK	-11492.0
CDH1	-11512.0
H2AW	-11543.0
NUP188	-11545.0
PARP16	-11583.0
PARP1	-11586.0
FCGR3A	-11661.0
RANGAP1	-11665.0
VAMP2	-11692.0
GPR20	-11696.0
NUP93	-11700.0
SLC25A4	-11722.0
FYN	-11758.0
PTGER4	-11767.0
PRKACB	-11857.0
KPNA5	-11861.0
ADRB2	-11879.0
ST6GAL1	-11887.0
PARP14	-11897.0
RNF213	-11921.0
NMT2	-11923.0
SCT	-11927.0
PTGDR	-11967.0
APOBEC3G	-11978.0
GNGT2	-12070.0
RBBP7	-12085.0
GIPR	-12098.0
ISG15	-12099.0
NDC1	-12113.0
YES1	-12143.0
VIPR2	-12157.0
C3	-12243.0
CD247	-12295.0

---

Class I MHC mediated antigen processing & presentation

	188
set	Class I MHC mediated antigen processing & presentation
setSize	350
pANOVA	5.2e-08
s.dist	0.169
p.adjustANOVA	9.45e-07

Top enriched genes

GeneID	Gene Rank
SOCS3	9526
CD36	9486
FBXO9	9467
FBXL5	9458
FCGR1A	9397
NCF4	9365
UBE2J1	9272
KLHL2	9252
NCF2	9209
FCGR1B	9168
CD14	9164
UBE2D1	9125
TLR2	9069
TLR1	9041
CYBB	9000
TRIM71	8989
TLR4	8981
TLR6	8931
LY96	8871
MKRN1	8864

Click HERE to show all gene set members

GeneID	Gene Rank
SOCS3	9526
CD36	9486
FBXO9	9467
FBXL5	9458
FCGR1A	9397
NCF4	9365
UBE2J1	9272
KLHL2	9252
NCF2	9209
FCGR1B	9168
CD14	9164
UBE2D1	9125
TLR2	9069
TLR1	9041
CYBB	9000
TRIM71	8989
TLR4	8981
TLR6	8931
LY96	8871
MKRN1	8864
FBXL19	8733
CDC34	8728
UBE2D3	8710
TRAF7	8658
SIAH2	8657
SNAP23	8578
UBE2R2	8564
PSMB7	8535
PSMD4	8498
RNF130	8485
RNF41	8473
RNF217	8422
UBE2J2	8389
PSME3	8331
UBAC1	8301
CTSS	8300
PSMB5	8188
SEC24D	8130
VAMP3	8121
MYD88	8091
ATG7	8065
RNF7	7977
NEDD4L	7972
CHUK	7959
UBE2W	7932
PSMD6	7881
WSB1	7840
UBE2H	7815
NPEPPS	7777
UBA3	7776
SEC24A	7716
PSMD9	7712
RNF144B	7710
ZNRF1	7691
ELOC	7637
UBE2L3	7612
LRRC41	7609
UBE2M	7590
ELOB	7586
FBXO7	7577
PJA2	7536
PSMD2	7470
UBE2F	7462
NCF1	7433
SEC23A	7416
RNF182	7415
PSMA1	7346
UBE2A	7315
PSMD1	7283
PSMB3	7265
UBA1	7187
PSMA7	7174
BTK	7156
UBE2B	7129
SEC61B	7125
HSPA5	7118
PSMC1	7096
ITGB5	7004
TRIP12	6977
CYBA	6952
PSMB6	6927
CUL3	6924
RNF123	6899
RNF19B	6857
UBE2E1	6853
UBE2K	6832
FBXO11	6747
UBB	6737
PSMF1	6724
PSMC6	6701
FBXW2	6635
AREL1	6569
KBTBD7	6566
SAR1B	6562
PSMD12	6537
SEC61A1	6517
RCHY1	6483
CALR	6415
NEDD4	6330
ASB7	6322
PSMD11	6296
FBXW11	6282
UBE3C	6272
ANAPC11	6249
ITGAV	6133
PSMD7	6017
PSMD13	5991
PSMA6	5978
SEC22B	5939
UBE2Q1	5866
PSMD8	5845
RNF111	5821
SEC13	5820
MGRN1	5764
TIRAP	5700
UBE2V1	5681
FBXL13	5592
FBXL4	5572
RLIM	5540
CANX	5526
IKBKG	5434
PSMA2	5433
VAMP8	5284
UBE2C	5168
KLHL5	5154
UBE2E3	5089
KLHL21	5069
UBE2G1	5016
KEAP1	5003
ASB8	4973
HERC4	4964
FBXL20	4911
LRSAM1	4895
HECW2	4874
SEC61G	4837
UBE2S	4810
FBXO30	4752
UBE2D2	4721
PSMD3	4693
LONRF1	4604
CTSL	4583
FBXL15	4533
SEM1	4436
KCTD6	4434
UBC	4421
RNF138	4394
RNF14	4383
SKP1	4349
PDIA3	4172
UBR2	4140
PSMB2	4103
CDC20	4087
RBX1	4039
FBXL8	4029
RNF6	3988
SOCS1	3886
VHL	3742
SEC24B	3655
FBXO17	3537
PSMD5	3507
UBA6	3490
PSMB1	3422
FBXL18	3388
ASB13	3383
ASB1	3318
MRC1	3187
TAPBP	3075
BLMH	3071
UBE3A	3047
CDC26	3013
RNF114	3010
UBE2V2	2997
ANAPC13	2930
PSMD14	2703
PSMC2	2696
CUL2	2559
PSMB4	2552
TRIM21	2467
FBXO40	2452
TRIM41	2419
SPSB1	2416
BTBD1	2261
RBCK1	2239
UBE2O	2107
TRIM4	2051
TRIM9	2050
PSMC3	2018
UBE4A	1987
UBE2N	1951
UBE3B	1900
UBE2E2	1781
PSMD10	1646
ASB9	1560
ITCH	1394
ASB3	1343
KLHL9	1277
HECTD3	1254
ZBTB16	1252
SEC31A	1144
UBA52	1071
HLA-C	1032
FBXL3	1026
HERC3	1024
CUL5	847
ZNRF2	714
HLA-B	658
STX4	626
FBXW5	244
KLHL13	-4
MRC2	-90
PSMA4	-538
CDC27	-659
FBXO41	-664
PSMC5	-948
UBOX5	-959
STUB1	-1093
FBXO15	-1131
RBBP6	-1139
FBXL12	-1327
GAN	-1402
UBR4	-2107
UNKL	-2197
ASB14	-2209
FZR1	-2253
FBXO6	-2328
HLA-G	-2370
HECTD1	-2504
LTN1	-2562
HLA-A	-2578
SMURF1	-2584
SEC24C	-2615
ASB6	-2780
CTSV	-2816
SIAH1	-3004
PSMB8	-3080
CUL7	-3371
KBTBD6	-3608
TRIM11	-3724
FBXO22	-3743
HLA-H	-3892
MYLIP	-4005
SPSB2	-4099
KBTBD8	-4233
HLA-E	-4448
UBR1	-4802
LNX1	-4847
BTRC	-4932
ANAPC10	-5074
SH3RF1	-5092
FBXO27	-5112
ANAPC7	-5259
BTBD6	-5265
ERAP2	-5268
IKBKB	-5290
PSMA3	-5314
DTX3L	-5531
ASB4	-5677
PSMB10	-5768
HACE1	-5874
CDC16	-6037
FBXL14	-6062
PSME4	-6099
KLHL11	-6134
PSMA5	-6154
RNF34	-6162
RNF220	-6371
FBXO10	-6411
FBXW7	-6709
FBXL16	-6710
ASB16	-6721
TRIM36	-6733
ANAPC4	-6780
UFL1	-6788
RPS27A	-6894
B2M	-7019
ERAP1	-7234
ANAPC2	-7284
RNF25	-7377
FBXW9	-7412
UBA7	-7455
PSMA8	-7559
LRR1	-7760
TRIM37	-7861
UBE2G2	-7879
HUWE1	-8044
FBXO2	-8199
UBA5	-8208
SKP2	-8307
KLHL42	-8445
FBXW12	-8474
TPP2	-8756
HECTD2	-8878
DET1	-9075
FBXO44	-9242
PSMC4	-9306
FBXL22	-9326
THOP1	-9344
HERC1	-9355
LMO7	-9377
CCNF	-9479
PJA1	-9565
RNF115	-9751
TRIM69	-9817
LNPEP	-9853
FBXW8	-10006
WWP1	-10036
PSME1	-10138
SMURF2	-10250
KLHL25	-10363
RNF19A	-10380
PSME2	-10415
TRIM39	-10450
RNF126	-10705
TAP1	-10727
HERC2	-10745
HLA-F	-10771
FBXO32	-10797
DZIP3	-10816
FBXO21	-10844
UBE3D	-10854
SEC61A2	-10873
KCTD7	-10994
MIB2	-11044
KLHL22	-11058
UBE2Z	-11084
ANAPC5	-11108
GLMN	-11202
KLHL3	-11236
CDC23	-11349
UBE2D4	-11360
PSMB9	-11362
TRIM32	-11375
UBE2L6	-11415
CUL1	-11467
TRAIP	-11468
KLHL20	-11500
RNF4	-11568
FBXW4	-11593
UBE2Q2	-11642
TAP2	-11828
FBXO4	-11867
ANAPC1	-11870
FBXO31	-11894
RNF213	-11921
ASB2	-12015
ARIH2	-12087
MEX3C	-12106
HERC6	-12199
HERC5	-12225
CBLB	-12266

---

The citric acid (TCA) cycle and respiratory electron transport

	1228
set	The citric acid (TCA) cycle and respiratory electron transport
setSize	172
pANOVA	6.43e-08
s.dist	0.239
p.adjustANOVA	1.15e-06

Top enriched genes

GeneID	Gene Rank
BSG	9214
ME1	8961
SLC16A3	8884
LDHA	8743
ETFA	8614
NDUFB3	8536
SDHC	8512
NDUFB9	8336
NDUFAF1	8295
UQCRH	8187
ETFDH	8086
UQCRC1	7829
COX7A2L	7808
ETFB	7772
SUCLA2	7667
NDUFB1	7664
ATP5PB	7663
ATP5PD	7656
SDHB	7568
RXRA	7513

Click HERE to show all gene set members

GeneID	Gene Rank
BSG	9214
ME1	8961
SLC16A3	8884
LDHA	8743
ETFA	8614
NDUFB3	8536
SDHC	8512
NDUFB9	8336
NDUFAF1	8295
UQCRH	8187
ETFDH	8086
UQCRC1	7829
COX7A2L	7808
ETFB	7772
SUCLA2	7667
NDUFB1	7664
ATP5PB	7663
ATP5PD	7656
SDHB	7568
RXRA	7513
DLD	7253
NDUFAF3	7092
SDHD	7024
UQCR11	7005
ME2	6969
TIMMDC1	6842
COX8A	6712
ATP5F1C	6627
ATP5MF	6615
NDUFA4	6586
ATP5F1A	6536
ATP5F1B	6524
ATP5PF	6488
NDUFS1	6345
COX5B	6328
UQCRFS1	6294
ATP5F1E	6259
NDUFS5	6252
COX5A	6238
NDUFC2	6199
NDUFS2	6169
NDUFA6	6108
SUCLG1	6053
ATP5MC3	6010
NDUFB10	5889
UQCRC2	5885
PDK4	5854
NDUFAB1	5846
NDUFA1	5827
COX6B1	5755
NDUFA7	5698
ATP5MG	5608
GSTZ1	5456
NDUFC1	5436
NDUFV3	5191
COX6A1	5167
HAGH	5151
NDUFA2	5018
ECSIT	4997
NDUFA8	4885
ATP5PO	4868
MPC2	4629
NDUFB4	4594
COX7B	4554
SLC16A1	4517
TACO1	4468
NNT	4452
UQCR10	4424
NDUFV2	4345
PDHX	4344
VDAC1	4300
NDUFA13	4294
PDHB	4292
PDK1	4269
MDH2	4266
NDUFB6	4265
NDUFS6	4258
COX4I1	4252
ACO2	4228
OGDH	4138
COQ10B	4065
NDUFS4	4035
NDUFB5	3970
UQCRB	3916
CS	3685
SURF1	3585
IDH3G	3353
PDK3	3304
CYC1	3139
ATP5MC2	3017
ATP5F1D	3007
UQCRQ	2981
FH	2955
NDUFAF7	2695
ATP5ME	2673
NDUFB7	2332
NDUFAF2	2174
NDUFS7	2129
SLC16A8	2015
NDUFA11	1471
NDUFB11	1201
NDUFB8	974
UCP2	969
NDUFS3	929
MT-ND4	830
COX6C	721
MT-CO1	675
COX7C	558
NDUFA3	528
MT-ND6	453
COX16	214
FAHD1	203
NDUFS8	80
MT-CO3	47
MT-CO2	35
ACAD9	-904
MPC1	-945
CYCS	-1282
COX14	-1508
IDH3B	-1521
NDUFA12	-1763
MT-ATP6	-2106
MT-ND5	-2218
NDUFAF6	-2303
MT-CYB	-2314
LDHAL6A	-2544
IDH2	-2943
MT-ATP8	-2961
DLAT	-3566
MT-ND3	-3687
MT-ND1	-3693
GLO1	-3779
SCO2	-4299
PDP1	-4302
SLC25A27	-4389
NDUFB2	-4470
PDHA1	-4484
SLC25A14	-4687
NDUFA5	-4736
COX20	-5036
ADHFE1	-5066
SDHA	-5523
D2HGDH	-5708
SUCLG2	-5863
PPARD	-6092
COX18	-6129
MT-ND2	-6660
COX19	-6928
NDUFA10	-7022
DMAC2L	-7416
PDPR	-7428
ATP5MC1	-7598
PDK2	-8114
TMEM126B	-8426
NDUFA9	-8944
DLST	-9072
IDH3A	-9425
NDUFAF5	-9710
LDHB	-9712
SCO1	-9862
NDUFAF4	-9891
L2HGDH	-10075
PM20D1	-10109
LRPPRC	-10120
ME3	-10128
UCP3	-10264
TRAP1	-10800
COX11	-11085
PDP2	-11174
COQ10A	-11185
NDUFV1	-11489
NUBPL	-11590

---

COPII-mediated vesicle transport

	135
set	COPII-mediated vesicle transport
setSize	65
pANOVA	6.58e-08
s.dist	0.387
p.adjustANOVA	1.17e-06

Top enriched genes

GeneID	Gene Rank
F5	9524
SERPINA1	9179
RAB1A	9075
TGFA	9031
CTSZ	9001
NSF	8815
RAB1B	8407
SEC24D	8130
TRAPPC1	7887
CNIH1	7832
SEC24A	7716
SEC23A	7416
TFG	7240
STX5	7186
LMAN2	7178
TRAPPC3	7158
MCFD2	7136
LMAN2L	7003
F8	6996
PPP6C	6887

Click HERE to show all gene set members

GeneID	Gene Rank
F5	9524
SERPINA1	9179
RAB1A	9075
TGFA	9031
CTSZ	9001
NSF	8815
RAB1B	8407
SEC24D	8130
TRAPPC1	7887
CNIH1	7832
SEC24A	7716
SEC23A	7416
TFG	7240
STX5	7186
LMAN2	7178
TRAPPC3	7158
MCFD2	7136
LMAN2L	7003
F8	6996
PPP6C	6887
GORASP1	6670
SAR1B	6562
PREB	6450
COL7A1	6375
GOLGA2	6217
TMED2	6098
CD59	5964
SEC22B	5939
SEC13	5820
AREG	5494
TRAPPC9	5414
PPP6R1	5328
YKT6	5277
TRAPPC5	5253
SEC16A	4687
TRAPPC6B	4201
USO1	4192
NAPG	4190
SEC24B	3655
SCFD1	3593
PPP6R3	3323
CTSC	2547
CSNK1D	2412
NAPA	1385
SEC31A	1144
CNIH2	727
SEC16B	351
TMED10	328
TBC1D20	-49
SEC23IP	-469
BET1	-631
GOSR2	-1504
TRAPPC2L	-2337
SEC24C	-2615
NAPB	-2763
SEC22C	-4285
SEC22A	-5080
ANKRD28	-6311
TRAPPC4	-6836
TRAPPC2	-8851
CNIH3	-9196
TRAPPC10	-9516
LMAN1	-10699
TRAPPC6A	-10921
STX17	-11009

---

ESR-mediated signaling

	333
set	ESR-mediated signaling
setSize	161
pANOVA	7.12e-08
s.dist	0.246
p.adjustANOVA	1.25e-06

Top enriched genes

GeneID	Gene Rank
CTSD	9475
GNG10	9436
H2AJ	9418
MMP9	9370
H2BC21	9368
H2BC12	9178
CARM1	9122
AGO4	9094
MAPK3	9078
TGFA	9031
FKBP5	8936
GNG5	8866
H3-3A	8754
FOXO3	8729
TLE3	8679
ZDHHC7	8609
SP1	8315
GNB1	8278
EGF	8267
GNB2	8234

Click HERE to show all gene set members

GeneID	Gene Rank
CTSD	9475.0
GNG10	9436.0
H2AJ	9418.0
MMP9	9370.0
H2BC21	9368.0
H2BC12	9178.0
CARM1	9122.0
AGO4	9094.0
MAPK3	9078.0
TGFA	9031.0
FKBP5	8936.0
GNG5	8866.0
H3-3A	8754.0
FOXO3	8729.0
TLE3	8679.0
ZDHHC7	8609.0
SP1	8315.0
GNB1	8278.0
EGF	8267.0
GNB2	8234.0
H2BC5	8163.0
GNAI2	8094.0
H2BC11	8076.0
H2AC6	8070.0
KDM4B	8038.0
GNAI3	8027.0
TFF3	7871.0
SPHK1	7724.0
POLR2E	7660.0
RUNX1	7591.0
H2BC4	7549.0
MAPK1	7520.0
H2BC17	7502.0
GTF2A2	7207.0
SRF	7205.0
GNB4	7138.0
H3C15	6780.5
POLR2J	6769.0
GNG11	6612.0
USF2	6541.0
PDPK1	6209.0
EP300	6208.0
FOS	6179.0
H2AZ1	6126.0
IGF1R	6032.0
AGO1	5660.0
GTF2F2	5503.0
AREG	5494.0
H2BC9	5461.0
H2BC15	5458.0
NRAS	5411.0
POLR2L	5362.0
S1PR3	5343.0
STAG2	5339.0
PIK3R2	5051.0
GTF2F1	5042.0
H2AC20	5039.0
USF1	4893.0
HBEGF	4878.0
PPID	4758.0
PIK3CA	4697.0
POLR2F	4646.0
NRIP1	4616.0
CAV2	4602.0
NCOA1	4563.0
PTK2	4506.0
KCTD6	4434.0
GNG8	4339.0
PTGES3	4180.0
SHC1	4173.0
JUN	3964.0
MMP7	3952.0
KRAS	3760.0
STRN	3758.0
AKT1	3656.0
POLR2G	3581.0
NCOA3	3563.0
CREBBP	3460.0
GNAI1	3364.0
ZNF217	3266.0
AGO2	3046.0
GTF2A1	2744.0
EPGN	2579.0
MYC	2367.0
CBFB	2152.0
ATF2	2110.0
EREG	1906.0
CAV1	1856.0
RAD21	1719.0
POU2F1	1611.0
JUND	1561.0
POLR2C	1531.0
FOSB	1432.0
KAT5	1361.0
HSP90AA1	1348.0
NCOA2	1109.0
ELK1	1040.0
GNG3	894.0
FKBP4	788.0
SMC1A	659.0
MYB	555.0
YY1	529.0
GNB5	467.0
HDAC1	394.0
AKT2	345.0
POLR2I	316.0
CHD1	-6.0
AGO3	-1014.0
XPO1	-1199.0
H2AZ2	-1266.0
CREB1	-1382.0
NOS3	-1718.0
POLR2K	-1792.0
SMC3	-1982.0
CALM1	-2048.0
GNG4	-2175.0
KAT2B	-2393.0
POLR2B	-2536.0
GNB3	-2776.0
POLR2H	-2817.0
POLR2A	-3105.0
HRAS	-3335.0
UHMK1	-3901.0
KANK1	-3909.0
CDK9	-3988.0
POLR2D	-4058.0
MED1	-4082.0
BCL2	-4480.0
TNRC6B	-4558.0
GNG7	-5049.0
TNRC6A	-5567.0
ZDHHC21	-6207.0
STAG1	-6429.0
H2BU1	-6519.0
HSP90AB1	-6702.0
KPNA2	-6845.0
CCND1	-6847.0
GREB1	-6981.0
CXXC5	-7252.0
PPP5C	-7588.0
GNG2	-7809.0
CDKN1B	-8305.0
PRMT1	-8894.0
SRC	-9011.0
TBP	-9220.0
ESR1	-9230.0
ESR2	-9236.0
KDM1A	-9476.0
CCNT1	-9570.0
PIK3R1	-9725.0
DDX5	-9806.0
GPAM	-9993.0
AXIN1	-10310.0
EBAG9	-10325.0
PRKCZ	-11508.0
TNRC6C	-11737.0
AKT3	-11804.0
MOV10	-11980.0
PIK3R3	-12037.0
GNGT2	-12070.0
GATA3	-12140.0

---

Cellular responses to stress

	170
set	Cellular responses to stress
setSize	500
pANOVA	7.4e-08
s.dist	0.141
p.adjustANOVA	1.28e-06

Top enriched genes

GeneID	Gene Rank
H1-2	9553
GRB10	9508
LAMTOR1	9450
H2AJ	9418
LMNB1	9391
GPX1	9380
PRDX3	9378
H2BC21	9368
NCF4	9365
ATP6V1A	9301
ATP6V0D1	9298
GSR	9256
MAPK14	9219
NCF2	9209
H2BC12	9178
DCTN2	9158
CAT	9137
UBE2D1	9125
ATP6V1D	9118
ATP6V0C	9113

Click HERE to show all gene set members

GeneID	Gene Rank
H1-2	9553.0
GRB10	9508.0
LAMTOR1	9450.0
H2AJ	9418.0
LMNB1	9391.0
GPX1	9380.0
PRDX3	9378.0
H2BC21	9368.0
NCF4	9365.0
ATP6V1A	9301.0
ATP6V0D1	9298.0
GSR	9256.0
MAPK14	9219.0
NCF2	9209.0
H2BC12	9178.0
DCTN2	9158.0
CAT	9137.0
UBE2D1	9125.0
ATP6V1D	9118.0
ATP6V0C	9113.0
PHC2	9103.0
AGO4	9094.0
MAPK3	9078.0
ANAPC15	9035.0
MAP2K6	9010.0
YWHAE	9009.0
ATP6V1B2	9005.0
CYBB	9000.0
PRDX6	8986.0
FKBP5	8936.0
NUP58	8872.0
ERO1A	8853.0
RRAGD	8850.0
CDKN2B	8797.0
E2F2	8791.0
MAP2K3	8785.0
H3-3A	8754.0
UBE2D3	8710.0
KDM6B	8707.0
ATP6V0B	8701.0
ATP6V0E1	8662.0
RB1	8649.0
ATP6V1C1	8628.0
PRDX5	8612.0
LAMTOR5	8611.0
PSMB7	8535.0
EIF2AK1	8533.0
CAPZA2	8521.0
MAP4K4	8508.0
TFDP1	8500.0
PSMD4	8498.0
P4HB	8452.0
TXN	8414.0
DCTN4	8385.0
BAG4	8384.0
PSME3	8331.0
SP1	8315.0
TXNRD1	8303.0
MAPKAPK3	8255.0
PSMB5	8188.0
HSBP1	8182.0
HSPA1A	8178.0
CAPZA1	8165.0
H2BC5	8163.0
STAT3	8152.0
ATP6V1H	8119.0
CEBPB	8108.0
ATP6V1E1	8107.0
H2BC11	8076.0
ARNT	8074.0
H2AC6	8070.0
CAPZB	8057.0
DNAJB6	8053.0
ETS2	8024.0
NUP214	8011.0
EPAS1	8002.0
CDKN2D	8001.0
AKT1S1	7902.0
PSMD6	7881.0
RPS6KA1	7800.0
MAP3K5	7720.0
PSMD9	7712.0
LAMTOR2	7704.0
LAMTOR3	7692.0
RHEB	7675.0
ACTR10	7652.0
ELOC	7637.0
DYNC1I2	7629.0
H1-0	7598.0
DNAJC7	7594.0
ELOB	7586.0
TXNRD2	7556.0
H2BC4	7549.0
MAPK1	7520.0
H2BC17	7502.0
PSMD2	7470.0
HIGD1A	7465.0
NCF1	7433.0
HIF1A	7404.0
VEGFA	7389.0
DCTN6	7382.0
BMT2	7372.0
PSMA1	7346.0
RPL26L1	7295.0
PSMD1	7283.0
TCIRG1	7266.0
PSMB3	7265.0
HSPA2	7213.0
PSMA7	7174.0
HSPA5	7118.0
PRDX1	7104.0
PSMC1	7096.0
ACTR1A	7088.0
CDKN2C	7019.0
DYNC1LI1	6992.0
VCP	6955.0
CYBA	6952.0
MAP2K4	6948.0
PSMB6	6927.0
UBE2E1	6853.0
EIF2S3	6808.0
H3C15	6780.5
IGFBP7	6753.0
E2F3	6744.0
UBB	6737.0
PSMF1	6724.0
GSK3B	6720.0
PSMC6	6701.0
EGLN1	6700.0
HSPA6	6580.0
PSMD12	6537.0
HSPA1B	6495.0
E2F1	6473.0
CITED2	6467.0
BAG1	6455.0
NFKB1	6367.0
KPTN	6353.0
RRAGA	6344.0
ATF4	6317.0
PSMD11	6296.0
ANAPC11	6249.0
EP300	6208.0
EIF2S2	6203.0
FOS	6179.0
HSF1	6139.0
H2AZ1	6126.0
DCTN3	6080.0
DYNLL1	6049.0
PPP1R15A	6033.0
PSMD7	6017.0
PSMD13	5991.0
PSMA6	5978.0
ATP6V1F	5949.0
PSMD8	5845.0
SEC13	5820.0
ATP6V1E2	5776.0
FNIP1	5671.0
DNAJA2	5663.0
AGO1	5660.0
CEBPG	5551.0
CBX8	5523.0
RPS9	5496.0
DNAJA1	5489.0
H2BC9	5461.0
H2BC15	5458.0
PSMA2	5433.0
UBN1	5423.0
HSPA4	5416.0
CCNE2	5178.0
UBE2C	5168.0
RAE1	5152.0
DCTN1	5143.0
TERF2IP	5118.0
H2AC20	5039.0
RRAGC	5033.0
DDIT3	4938.0
AR	4913.0
ID1	4819.0
UBE2S	4810.0
TXN2	4728.0
UBE2D2	4721.0
PSMD3	4693.0
TINF2	4667.0
NPRL3	4564.0
NUP50	4544.0
RPL3L	4539.0
LAMTOR4	4487.0
SOD2	4458.0
ATOX1	4439.0
CDKN1A	4438.0
SEM1	4436.0
UBC	4421.0
ERF	4412.0
EIF2S1	4338.0
DYNC1LI2	4253.0
DYNC1I1	4211.0
PTGES3	4180.0
MDM2	4179.0
MAPKAPK2	4176.0
MAPK10	4136.0
PSMB2	4103.0
CBX6	4091.0
RBX1	4039.0
ATP6V1G1	3989.0
JUN	3964.0
MAPK11	3955.0
VHL	3742.0
MINK1	3727.0
FLCN	3639.0
SESN2	3606.0
RNF2	3573.0
PSMD5	3507.0
EGLN2	3497.0
PRDX2	3467.0
CREBBP	3460.0
MIOS	3424.0
PSMB1	3422.0
DEDD2	3360.0
RPS6KA2	3177.0
NUP37	3153.0
NUP98	3124.0
HSPA1L	3102.0
NUDT2	3089.0
H1-4	3026.0
CDC26	3013.0
RPS6KA3	3012.0
VENTX	2938.0
SLC38A9	2861.0
RPS19BP1	2712.0
PSMD14	2703.0
PSMC2	2696.0
CUL2	2559.0
PSMB4	2552.0
HSPA12B	2335.0
NBN	2243.0
CBX4	2237.0
MRPL18	2146.0
RPS27L	2117.0
ATF2	2110.0
PSMC3	2018.0
CAMK2G	1888.0
CXCL8	1797.0
CCNA2	1676.0
MAP2K7	1647.0
PSMD10	1646.0
CCS	1374.0
KAT5	1361.0
HSP90AA1	1348.0
NOX5	1279.0
WDR24	1129.0
NOX4	1116.0
UBA52	1071.0
GPX3	857.0
FKBP4	788.0
NUP62	772.0
ATP7A	647.0
NR3C1	600.0
CCNA1	575.0
MLST8	304.0
GSTP1	197.0
EIF2AK4	144.0
DEPDC5	114.0
RPL36AL	91.0
HMGA1	81.0
RPLP1	-65.0
HIKESHI	-85.0
RPS4Y1	-222.0
RPS24	-282.0
FAU	-402.0
EGLN3	-450.0
PSMA4	-538.0
CDC27	-659.0
RRAGB	-689.0
RANBP2	-808.0
DNAJA4	-872.0
PSMC5	-948.0
AGO3	-1014.0
RPL15	-1017.0
RPLP0	-1054.0
HSPA13	-1164.0
MDM4	-1218.0
RPL8	-1242.0
H2AZ2	-1266.0
CYCS	-1282.0
MAPK7	-1294.0
ST13	-1304.0
RPS26	-1443.0
RPL28	-1469.0
RPL22L1	-1643.0
HSPA12A	-1743.0
RPS13	-1759.0
RELA	-1807.0
RPL9	-1827.0
RBBP4	-1907.0
RPL7	-2018.0
RPS8	-2138.0
ANAPC16	-2165.0
STIP1	-2170.0
ATP6V1C2	-2222.0
FZR1	-2253.0
HIF3A	-2292.0
HSPA4L	-2347.0
FNIP2	-2391.0
SUZ12	-2444.0
RPL27	-2934.0
RPL39	-3047.0
NUP85	-3077.0
PSMB8	-3080.0
BAG3	-3167.0
IMPACT	-3242.0
RPL23	-3352.0
RPL6	-3382.0
RPL13	-3461.0
TERF1	-3548.0
GPX2	-3560.0
RPL4	-3592.0
RPL29	-3604.0
RPS15	-3698.0
RPL7A	-3699.0
RPL37A	-4004.0
DYNLL2	-4042.0
RING1	-4045.0
RPS21	-4115.0
DCTN5	-4140.0
SIRT1	-4217.0
POT1	-4395.0
RPL31	-4507.0
RPS2	-4509.0
TERF2	-4515.0
TNRC6B	-4558.0
HIF1AN	-4559.0
RPS16	-4570.0
RPL5	-4631.0
RPS28	-4647.0
CBX2	-4693.0
RPS3A	-4702.0
RPL22	-4738.0
BAG5	-4913.0
SOD1	-4927.0
DNAJC2	-5003.0
RPS7	-5016.0
CDK2	-5018.0
RPL18	-5054.0
EEF1A1	-5073.0
ANAPC10	-5074.0
SZT2	-5252.0
ANAPC7	-5259.0
RPL36	-5287.0
CDKN2A	-5302.0
PSMA3	-5314.0
ATF5	-5410.0
RPL17	-5464.0
RPS5	-5478.0
RPS14	-5485.0
SCMH1	-5553.0
TNRC6A	-5567.0
NUP42	-5622.0
DNAJB1	-5625.0
RPS10	-5686.0
RPS15A	-5695.0
PSMB10	-5768.0
RPS3	-5833.0
RPL24	-5882.0
RPL38	-5890.0
TRIB3	-5896.0
SEH1L	-5957.0
RPS4X	-5969.0
RPS12	-5985.0
RPL18A	-6029.0
CDC16	-6037.0
RPL35A	-6080.0
PSME4	-6099.0
RPS6	-6100.0
PSMA5	-6154.0
RLN1	-6210.0
RPSA	-6219.0
RPS17	-6223.0
RPL19	-6242.0
RPS25	-6246.0
RPL11	-6275.0
RPS23	-6279.0
RPL27A	-6321.0
NUP153	-6325.0
CDK6	-6379.0
RPA2	-6397.0
RPL37	-6401.0
RPL21	-6481.0
EP400	-6516.0
RPL14	-6518.0
H2BU1	-6519.0
RPL10	-6562.0
RPL32	-6577.0
RPL26	-6636.0
RPL10A	-6644.0
HSP90AB1	-6702.0
ANAPC4	-6780.0
RPL34	-6807.0
RPL41	-6877.0
RPS27A	-6894.0
RPLP2	-6915.0
RPL30	-6995.0
RPS19	-7037.0
RPL12	-7038.0
TPR	-7100.0
RPS11	-7122.0
MAPK9	-7182.0
ANAPC2	-7284.0
POM121C	-7305.0
WTIP	-7336.0
RPL36A	-7442.0
RAD50	-7482.0
BAG2	-7537.0
PSMA8	-7559.0
ACD	-7630.0
RPS18	-7641.0
RPS29	-7794.0
PHC1	-7816.0
DYNC1H1	-7822.0
NUP133	-7839.0
AJUBA	-7848.0
MRE11	-7888.0
RPL13A	-8123.0
PHC3	-8154.0
RPL35	-8239.0
POM121	-8263.0
ASNS	-8299.0
CDKN1B	-8305.0
AAAS	-8337.0
HDAC6	-8348.0
MAPKAPK5	-8452.0
RPL3	-8478.0
HSPA7	-8505.0
EHMT2	-8517.0
NUP54	-8521.0
EHMT1	-8729.0
RPS20	-8922.0
RPL39L	-8982.0
RPA3	-9003.0
WDR59	-9050.0
SH3BP4	-9054.0
GPX7	-9056.0
SESN1	-9083.0
HSPH1	-9227.0
ATP6V1G2	-9275.0
PSMC4	-9306.0
EED	-9417.0
RPL23A	-9477.0
HSPA14	-9589.0
NUP43	-9595.0
MAPK8	-9646.0
RPS27	-9651.0
BMI1	-9787.0
HIRA	-9836.0
ASF1A	-9865.0
EZH2	-9929.0
MTOR	-9948.0
ATF3	-9951.0
HSPA9	-9981.0
PSME1	-10138.0
SERPINH1	-10160.0
NUP35	-10206.0
CCAR2	-10253.0
GCN1	-10284.0
NUP155	-10291.0
NR3C2	-10304.0
NUP160	-10383.0
ATR	-10403.0
PSME2	-10415.0
CABIN1	-10427.0
RPTOR	-10494.0
NUP107	-10570.0
ITFG2	-10682.0
NUP210	-10725.0
ATM	-10839.0
HSPA8	-10913.0
TP53	-10936.0
LIMD1	-10961.0
C12orf66	-10966.0
NUP88	-11046.0
ANAPC5	-11108.0
CDK4	-11138.0
NUP205	-11250.0
ETS1	-11319.0
CDC23	-11349.0
PSMB9	-11362.0
NPRL2	-11435.0
ATP6V0E2	-11475.0
NUP188	-11545.0
TNIK	-11622.0
CCNE1	-11655.0
NUP93	-11700.0
CAMK2D	-11728.0
TNRC6C	-11737.0
ANAPC1	-11870.0
RPA1	-11962.0
MOV10	-11980.0
RBBP7	-12085.0
NDC1	-12113.0
TNFRSF21	-12219.0
TFDP2	-12315.0

---

trans-Golgi Network Vesicle Budding

	1363
set	trans-Golgi Network Vesicle Budding
setSize	69
pANOVA	9.74e-08
s.dist	0.371
p.adjustANOVA	1.66e-06

Top enriched genes

GeneID	Gene Rank
VAMP7	9549
AP1S1	9338
GNS	9309
SORT1	9208
APP	9123
ARF1	9083
CLTC	9056
PICALM	9052
CTSZ	9001
CPD	8901
CHMP2A	8863
AP1B1	8741
BLOC1S1	8726
FTL	8698
RAB5C	8688
TGOLN2	8647
SNAP23	8578
CLTA	8402
AP3B1	8377
AP3S1	7876

Click HERE to show all gene set members

GeneID	Gene Rank
VAMP7	9549
AP1S1	9338
GNS	9309
SORT1	9208
APP	9123
ARF1	9083
CLTC	9056
PICALM	9052
CTSZ	9001
CPD	8901
CHMP2A	8863
AP1B1	8741
BLOC1S1	8726
FTL	8698
RAB5C	8688
TGOLN2	8647
SNAP23	8578
CLTA	8402
AP3B1	8377
AP3S1	7876
SNX2	7821
SNAPIN	7535
IGF2R	7270
DNASE2	6841
BLOC1S6	6811
AP1M1	6788
OCRL	6436
AP4E1	6424
CLTB	6195
DNM2	6163
YIPF6	5924
ACBD3	5898
VAMP8	5284
FTH1	4867
DNAJC6	4706
HGS	4570
AP1G1	4052
CLINT1	3903
PUM1	3325
GAK	2606
NECAP1	2247
ARRB1	2098
AP1M2	1740
TFRC	1578
TBC1D8B	1399
NAPA	1385
DTNBP1	1153
STX4	626
TXNDC5	548
AP4M1	234
SNX9	-404
AP1S2	-2330
SNX5	-3179
TPD52L1	-3229
SH3D19	-4106
GBF1	-4322
PIK3C2A	-5233
AP1G2	-5381
GOLGB1	-5425
AP1S3	-5592
AP4S1	-5732
AP4B1	-7350
BLOC1S4	-7403
M6PR	-8665
BLOC1S3	-8808
TPD52	-9423
HIP1R	-10052
HSPA8	-10913
VAMP2	-11692

---

PD-1 signaling

	779
set	PD-1 signaling
setSize	28
pANOVA	1.17e-07
s.dist	-0.578
p.adjustANOVA	1.97e-06

Top enriched genes

GeneID	Gene Rank
CD247	-12295
HLA-DPA1	-12271
HLA-DPB1	-12203
HLA-DRA	-12007
TRBC1	-11859
HLA-DQA1	-11763
LCK	-11492
CD3G	-11409
CD3D	-11094
CD3E	-11042
TRAC	-10981
TRBV12-3	-10279
TRAV19	-10023
TRBV7-9	-9564
HLA-DQB2	-9390
TRAV8-4	-9384
TRAV29DV5	-9334
HLA-DRB1	-8159
PDCD1	-6963
CD274	-6803

Click HERE to show all gene set members

GeneID	Gene Rank
CD247	-12295
HLA-DPA1	-12271
HLA-DPB1	-12203
HLA-DRA	-12007
TRBC1	-11859
HLA-DQA1	-11763
LCK	-11492
CD3G	-11409
CD3D	-11094
CD3E	-11042
TRAC	-10981
TRBV12-3	-10279
TRAV19	-10023
TRBV7-9	-9564
HLA-DQB2	-9390
TRAV8-4	-9384
TRAV29DV5	-9334
HLA-DRB1	-8159
PDCD1	-6963
CD274	-6803
HLA-DQB1	-5703
CD4	-5320
HLA-DRB5	-5140
HLA-DQA2	-4793
PDCD1LG2	-3315
CSK	5285
PTPN11	5383
PTPN6	6176

---

rRNA modification in the nucleus and cytosol

	1353
set	rRNA modification in the nucleus and cytosol
setSize	59
pANOVA	1.46e-07
s.dist	-0.396
p.adjustANOVA	2.42e-06

Top enriched genes

GeneID	Gene Rank
NAT10	-11864
BMS1	-11612
PDCD11	-11549
NOP56	-11502
DKC1	-11479
UTP4	-11391
DDX47	-11150
WDR46	-11050
NOP14	-10925
NOL6	-10847
IMP4	-10678
UTP15	-10548
UTP20	-10433
HEATR1	-10256
NOL11	-10225
EMG1	-10162
FBL	-10108
RRP9	-10053
NOP58	-10035
THUMPD1	-9861

Click HERE to show all gene set members

GeneID	Gene Rank
NAT10	-11864
BMS1	-11612
PDCD11	-11549
NOP56	-11502
DKC1	-11479
UTP4	-11391
DDX47	-11150
WDR46	-11050
NOP14	-10925
NOL6	-10847
IMP4	-10678
UTP15	-10548
UTP20	-10433
HEATR1	-10256
NOL11	-10225
EMG1	-10162
FBL	-10108
RRP9	-10053
NOP58	-10035
THUMPD1	-9861
WDR75	-9808
NOP2	-9504
IMP3	-9295
KRR1	-8597
DHX37	-8302
DIMT1	-8084
MPHOSPH10	-7881
WDR43	-7562
GAR1	-7020
PNO1	-6955
SNU13	-6919
WDR3	-6598
RPS6	-6100
DCAF13	-5627
NOC4L	-5514
RPS14	-5485
RPS7	-5016
UTP6	-4523
RPS2	-4509
WDR36	-3840
NHP2	-3499
TBL3	-3473
UTP3	-2941
RRP7A	-2826
SNORD3A	-2302
UTP14A	-1797
UTP14C	-1641
RRP36	-1507
PWP2	-991
RCL1	-834
DDX52	502
TRMT112	586
TSR3	3909
FCF1	4556
UTP11	4710
DDX49	4940
UTP18	5163
RPS9	5496
NOP10	8462

---

RAB GEFs exchange GTP for GDP on RABs

	878
set	RAB GEFs exchange GTP for GDP on RABs
setSize	88
pANOVA	1.64e-07
s.dist	0.323
p.adjustANOVA	2.7e-06

Top enriched genes

GeneID	Gene Rank
RAB32	9504
RAB13	9443
RAB31	9353
RAB3IL1	9153
RAB1A	9075
SBF2	9037
YWHAE	9009
RAB10	8915
RAB7A	8775
RAB5C	8688
RAB27A	8504
RAB1B	8407
RAB3A	8247
RIN2	8238
RAB6A	8223
DENND3	7981
RAB18	7893
TRAPPC1	7887
DENND5A	7737
RIN1	7572

Click HERE to show all gene set members

GeneID	Gene Rank
RAB32	9504
RAB13	9443
RAB31	9353
RAB3IL1	9153
RAB1A	9075
SBF2	9037
YWHAE	9009
RAB10	8915
RAB7A	8775
RAB5C	8688
RAB27A	8504
RAB1B	8407
RAB3A	8247
RIN2	8238
RAB6A	8223
DENND3	7981
RAB18	7893
TRAPPC1	7887
DENND5A	7737
RIN1	7572
RABGEF1	7569
DENND1A	7406
GDI2	7337
RAB5A	7166
TRAPPC3	7158
ULK1	7143
RAB14	7090
RAB39A	7059
GAPVD1	6866
TRAPPC8	6827
RAB5B	6801
RIC1	6733
MON1B	6714
RAB8B	6617
TRAPPC12	6394
RAB21	6237
RAB6B	6149
DENND2C	6056
GDI1	5807
RAB3GAP1	5800
HPS1	5679
TRAPPC9	5414
TRAPPC11	5269
TRAPPC5	5253
RGP1	4599
RAB3GAP2	4478
CCZ1	4314
TRAPPC6B	4201
RAB9A	4177
RAB35	4030
RAB8A	3874
AKT1	3656
RAB27B	3588
RAB3IP	3276
ALS2	3234
DENND4B	3189
DENND6B	3049
CHM	2291
CCZ1B	1066
AKT2	345
ANKRD27	281
DENND6A	-405
RAB12	-874
CHML	-1348
RAB7B	-1528
TRAPPC2L	-2337
TRAPPC13	-2510
MON1A	-3035
DENND5B	-4020
DENND4A	-5472
RAB9B	-6471
TRAPPC4	-6836
DENND1C	-7293
DENND4C	-7590
ALS2CL	-7707
DENND2A	-8504
RAB38	-8811
TRAPPC2	-8851
DENND1B	-9482
TRAPPC10	-9516
RINL	-10520
SBF1	-10529
TRAPPC6A	-10921
RAB39B	-11350
HPS4	-11490
AKT3	-11804
MADD	-11931
DENND2D	-12158

---

Rab regulation of trafficking

	933
set	Rab regulation of trafficking
setSize	121
pANOVA	1.71e-07
s.dist	0.275
p.adjustANOVA	2.77e-06

Top enriched genes

GeneID	Gene Rank
RAB32	9504
RAB13	9443
TBC1D2	9355
RAB31	9353
RAB3IL1	9153
GABARAPL2	9150
RAB1A	9075
SBF2	9037
YWHAE	9009
TBC1D14	8995
RAB10	8915
RAB7A	8775
RAB11A	8715
RAB5C	8688
RAB27A	8504
RAB1B	8407
RAB3A	8247
RIN2	8238
RAB6A	8223
TBC1D10B	8158

Click HERE to show all gene set members

GeneID	Gene Rank
RAB32	9504
RAB13	9443
TBC1D2	9355
RAB31	9353
RAB3IL1	9153
GABARAPL2	9150
RAB1A	9075
SBF2	9037
YWHAE	9009
TBC1D14	8995
RAB10	8915
RAB7A	8775
RAB11A	8715
RAB5C	8688
RAB27A	8504
RAB1B	8407
RAB3A	8247
RIN2	8238
RAB6A	8223
TBC1D10B	8158
MAP1LC3B	8099
RAB4A	8050
DENND3	7981
GABARAP	7967
RAB18	7893
TRAPPC1	7887
DENND5A	7737
RIN1	7572
RABGEF1	7569
DENND1A	7406
RAB33B	7385
GDI2	7337
RAB5A	7166
TRAPPC3	7158
ULK1	7143
RAB14	7090
RAB39A	7059
GAPVD1	6866
TRAPPC8	6827
RAB5B	6801
RIC1	6733
MON1B	6714
RAB8B	6617
TBC1D7	6561
TRAPPC12	6394
RAB21	6237
RAB6B	6149
DENND2C	6056
GDI1	5807
RAB3GAP1	5800
HPS1	5679
TRAPPC9	5414
TRAPPC11	5269
TRAPPC5	5253
RGP1	4599
RAB3GAP2	4478
RAB11B	4445
CCZ1	4314
TRAPPC6B	4201
RAB9A	4177
RAB35	4030
RAB8A	3874
GGA3	3846
TBC1D13	3828
TBC1D15	3678
AKT1	3656
RAB27B	3588
TBC1D16	3385
RAB3IP	3276
TBC1D24	3254
ALS2	3234
DENND4B	3189
DENND6B	3049
GGA1	2327
CHM	2291
RABGAP1	2085
ARF6	1407
CCZ1B	1066
AKT2	345
ANKRD27	281
TBC1D3	73
TBC1D20	-49
DENND6A	-405
TSC2	-804
RAB12	-874
CHML	-1348
RAB7B	-1528
TSC1	-2097
TRAPPC2L	-2337
TRAPPC13	-2510
MON1A	-3035
DENND5B	-4020
DENND4A	-5472
RAB9B	-6471
GGA2	-6523
TRAPPC4	-6836
DENND1C	-7293
TBC1D25	-7519
DENND4C	-7590
ALS2CL	-7707
DENND2A	-8504
TBC1D17	-8705
RAB38	-8811
TRAPPC2	-8851
DENND1B	-9482
TRAPPC10	-9516
SYTL1	-9782
POLG	-9958
RINL	-10520
SBF1	-10529
TRAPPC6A	-10921
RAB33A	-11034
RAB39B	-11350
HPS4	-11490
TBC1D10C	-11564
RABEP1	-11712
OPTN	-11757
AKT3	-11804
MADD	-11931
TBC1D10A	-12038
DENND2D	-12158

---

MAP2K and MAPK activation

	611
set	MAP2K and MAPK activation
setSize	34
pANOVA	1.76e-07
s.dist	0.517
p.adjustANOVA	2.82e-06

Top enriched genes

GeneID	Gene Rank
MAPK3	9078
MAP2K1	8960
ITGA2B	8942
APBB1IP	8849
MARK3	8774
TLN1	8554
ARRB2	8517
ITGB3	8367
FN1	8294
IQGAP1	8189
RAF1	7991
LAMTOR2	7704
LAMTOR3	7692
MAPK1	7520
VCL	7380
RAP1A	7319
MAP2K2	6906
VWF	6607
YWHAB	6398
NRAS	5411

Click HERE to show all gene set members

GeneID	Gene Rank
MAPK3	9078
MAP2K1	8960
ITGA2B	8942
APBB1IP	8849
MARK3	8774
TLN1	8554
ARRB2	8517
ITGB3	8367
FN1	8294
IQGAP1	8189
RAF1	7991
LAMTOR2	7704
LAMTOR3	7692
MAPK1	7520
VCL	7380
RAP1A	7319
MAP2K2	6906
VWF	6607
YWHAB	6398
NRAS	5411
CSK	5285
KSR1	4113
WDR83	3802
KRAS	3760
RAP1B	3331
ARAF	2680
ARRB1	2098
BRAF	1314
HRAS	-3335
KSR2	-3364
CNKSR2	-4481
CNKSR1	-6858
SRC	-9011
PEBP1	-11270

---

DNA strand elongation

	247
set	DNA strand elongation
setSize	32
pANOVA	2.48e-07
s.dist	-0.527
p.adjustANOVA	3.94e-06

Top enriched genes

GeneID	Gene Rank
MCM3	-12163
POLA1	-12121
MCM7	-12004
RPA1	-11962
RFC5	-11754
POLA2	-11639
MCM8	-10989
FEN1	-10740
GINS3	-10524
RFC3	-10515
RFC4	-10511
LIG1	-10471
GINS4	-10394
PRIM1	-10176
MCM6	-9941
POLD2	-9925
RPA3	-9003
MCM4	-8819
RFC1	-7529
MCM5	-7430

Click HERE to show all gene set members

GeneID	Gene Rank
MCM3	-12163
POLA1	-12121
MCM7	-12004
RPA1	-11962
RFC5	-11754
POLA2	-11639
MCM8	-10989
FEN1	-10740
GINS3	-10524
RFC3	-10515
RFC4	-10511
LIG1	-10471
GINS4	-10394
PRIM1	-10176
MCM6	-9941
POLD2	-9925
RPA3	-9003
MCM4	-8819
RFC1	-7529
MCM5	-7430
MCM2	-7316
RPA2	-6397
PCNA	-6038
PRIM2	-5619
GINS2	-4841
GINS1	-4435
DNA2	-2882
CDC45	-2683
POLD1	133
RFC2	5040
POLD4	6429
POLD3	8712

---

Post-translational protein phosphorylation

	842
set	Post-translational protein phosphorylation
setSize	70
pANOVA	3.12e-07
s.dist	0.354
p.adjustANOVA	4.9e-06

Top enriched genes

GeneID	Gene Rank
FAM20A	9572
VCAN	9538
F5	9524
FAM20C	9489
LAMC1	9473
CKAP4	9420
FSTL3	9363
QSOX1	9302
APLP2	9296
PCSK9	9229
SERPINA1	9179
APP	9123
LGALS1	9062
PNPLA2	9033
NUCB1	8917
ADAM10	8705
TGOLN2	8647
TIMP1	8594
DNAJC3	8468
P4HB	8452

Click HERE to show all gene set members

GeneID	Gene Rank
FAM20A	9572
VCAN	9538
F5	9524
FAM20C	9489
LAMC1	9473
CKAP4	9420
FSTL3	9363
QSOX1	9302
APLP2	9296
PCSK9	9229
SERPINA1	9179
APP	9123
LGALS1	9062
PNPLA2	9033
NUCB1	8917
ADAM10	8705
TGOLN2	8647
TIMP1	8594
DNAJC3	8468
P4HB	8452
FN1	8294
FUCA2	8195
GAS6	8164
LTBP1	8000
FSTL1	7961
CALU	7894
MELTF	7403
IGFBP7	6753
ANO8	6166
LAMB1	5948
PDIA6	5943
APOA2	5784
PRKCSH	5300
TMEM132A	5273
SDC2	5257
FBN1	5107
C4A	4491
SERPINA10	3885
MFGE8	3718
ALB	3339
KTN1	3322
MBTPS1	2958
MSLN	2273
CST3	2157
HSP90B1	2086
SHISA5	1280
TF	1172
LAMB2	494
APOE	103
CP	-1599
CSF1	-2030
SERPIND1	-2671
BMP4	-4078
ENAM	-4228
TNC	-4350
MGAT4A	-5545
MIA3	-6330
ITIH2	-6715
FGF23	-6840
GOLM1	-6954
MXRA8	-7275
IGFBP4	-7686
APOL1	-7788
MEN1	-8265
IGFBP3	-9669
WFS1	-9727
PROC	-10273
RCN1	-10928
C3	-12243
PRSS23	-12259

---

tRNA processing

	1360
set	tRNA processing
setSize	136
pANOVA	3.25e-07
s.dist	-0.254
p.adjustANOVA	5.04e-06

Top enriched genes

GeneID	Gene Rank
MT-TP	-12308
TSEN54	-12197
NDC1	-12113
TP53RK	-11910
ELAC2	-11818
THADA	-11775
NUP93	-11700
ALKBH8	-11600
NUP188	-11545
NUP205	-11250
NUP88	-11046
TSEN2	-10978
TRMT11	-10929
NUP210	-10725
THG1L	-10686
NUP107	-10570
NUP160	-10383
NUP155	-10291
LCMT2	-10228
NUP35	-10206

Click HERE to show all gene set members

GeneID	Gene Rank
MT-TP	-12308
TSEN54	-12197
NDC1	-12113
TP53RK	-11910
ELAC2	-11818
THADA	-11775
NUP93	-11700
ALKBH8	-11600
NUP188	-11545
NUP205	-11250
NUP88	-11046
TSEN2	-10978
TRMT11	-10929
NUP210	-10725
THG1L	-10686
NUP107	-10570
NUP160	-10383
NUP155	-10291
LCMT2	-10228
NUP35	-10206
TSEN15	-10086
ADAT2	-9667
CPSF4	-9615
TRMT13	-9609
NUP43	-9595
WDR4	-9491
TRMT61A	-9490
ADAT1	-9365
CDKAL1	-9308
POP5	-9307
TYW1	-9279
TRMU	-9164
QTRT1	-9145
CTU2	-8812
NUP54	-8521
MTO1	-8475
RPP25	-8346
AAAS	-8337
FTSJ1	-8298
FAM98B	-8266
POM121	-8263
TYW3	-8233
RPP30	-8204
TRMT61B	-8001
NUP133	-7839
TRNT1	-7612
NSUN6	-7346
POM121C	-7305
GTPBP3	-7242
TPR	-7100
MT-TL2	-7049
RAN	-6874
RPP38	-6855
METTL1	-6816
OSGEP	-6735
MT-TE	-6664
MT-ND2	-6660
TRMT44	-6612
CSTF2	-6390
NUP153	-6325
PUS1	-6065
SEH1L	-5957
C2orf49	-5756
NUP42	-5622
MT-TY	-5338
PUS7	-5254
RPP21	-5229
TPRKB	-5219
MT-TN	-4827
RPP40	-4722
TRMT10C	-4493
MT-TC	-4168
POP1	-4086
MT-TA	-4041
CPSF1	-3801
POP4	-3793
MT-TV	-3737
MT-ND1	-3693
MT-ND3	-3687
EPRS1	-3205
NUP85	-3077
TRMT1	-3039
MT-TS1	-3027
MT-ATP8	-2961
MT-TL1	-2879
DDX1	-2803
MT-TF	-2732
XPOT	-2720
MT-CYB	-2314
MT-ND5	-2218
MT-ATP6	-2106
MT-ND4L	-2067
NSUN2	-1867
LAGE3	-1834
MT-TM	-1490
RTCB	-1351
TYW5	-1213
URM1	-1202
RANBP2	-808
TRMT12	-401
MT-RNR1	-288
MT-CO2	35
MT-CO3	47
MT-ND6	453
TRMT112	586
MT-CO1	675
TRIT1	769
NUP62	772
MT-ND4	830
TRDMT1	913
ADAT3	1093
TRMT5	1124
RPPH1	1782
MT-RNR2	2190
QTRT2	2353
RPP14	3109
NUP98	3124
NUP37	3153
PRORP	3415
DUS2	3504
PUS3	3665
POP7	4213
RTRAF	4251
HSD17B10	4284
ZBTB8OS	4313
NUP50	4544
CTU1	4655
RAE1	5152
SEC13	5820
TRMT6	5857
CLP1	6691
TRMT10A	6937
TSEN34	7617
TRMT9B	7814
NUP214	8011
NUP58	8872

---

CLEC7A (Dectin-1) signaling

	131
set	CLEC7A (Dectin-1) signaling
setSize	97
pANOVA	3.39e-07
s.dist	0.3
p.adjustANOVA	5.2e-06

Top enriched genes

GeneID	Gene Rank
UBE2D1	9125
SYK	9087
PRKCD	9012
PYCARD	8734
CDC34	8728
PSMB7	8535
PSMD4	8498
PSME3	8331
PPP3R1	8240
PSMB5	8188
CHUK	7959
PSMD6	7881
UBA3	7776
PSMD9	7712
UBE2M	7590
PSMD2	7470
PSMA1	7346
PSMD1	7283
PSMB3	7265
PSMA7	7174

Click HERE to show all gene set members

GeneID	Gene Rank
UBE2D1	9125
SYK	9087
PRKCD	9012
PYCARD	8734
CDC34	8728
PSMB7	8535
PSMD4	8498
PSME3	8331
PPP3R1	8240
PSMB5	8188
CHUK	7959
PSMD6	7881
UBA3	7776
PSMD9	7712
UBE2M	7590
PSMD2	7470
PSMA1	7346
PSMD1	7283
PSMB3	7265
PSMA7	7174
PSMC1	7096
TAB2	7070
PPP3CB	6998
PSMB6	6927
NFKBIA	6835
UBB	6737
PSMF1	6724
PSMC6	6701
CARD9	6650
PSMD12	6537
AHCYL1	6475
NFKB1	6367
PPP3CA	6327
PSMD11	6296
FBXW11	6282
PDPK1	6209
PSMD7	6017
PSMD13	5991
PSMA6	5978
BCL10	5931
ITPR2	5919
PSMD8	5845
TAB1	5711
UBE2V1	5681
CLEC7A	5515
IKBKG	5434
PSMA2	5433
PLCG2	5103
IL1B	4830
UBE2D2	4721
PSMD3	4693
SEM1	4436
UBC	4421
SKP1	4349
PSMB2	4103
RELB	3767
PSMD5	3507
PSMB1	3422
TAB3	3165
PSMD14	2703
PSMC2	2696
PSMB4	2552
MAP3K7	2453
PSMC3	2018
UBE2N	1951
PSMD10	1646
UBA52	1071
TRAF6	-241
PSMA4	-538
NFKB2	-865
PSMC5	-948
RELA	-1807
CALM1	-2048
PSMB8	-3080
BTRC	-4932
IKBKB	-5290
PSMA3	-5314
PSMB10	-5768
PSME4	-6099
PSMA5	-6154
RPS27A	-6894
ITPR1	-7553
PSMA8	-7559
SRC	-9011
PSMC4	-9306
NFATC1	-9315
ITPR3	-9955
PSME1	-10138
PSME2	-10415
MALT1	-10701
PSMB9	-11362
CASP8	-11463
CUL1	-11467
MAP3K14	-11478
CARD11	-12035
NFATC3	-12139
NFATC2	-12236

---

Signaling by BRAF and RAF fusions

	1075
set	Signaling by BRAF and RAF fusions
setSize	57
pANOVA	3.58e-07
s.dist	0.39
p.adjustANOVA	5.43e-06

Top enriched genes

GeneID	Gene Rank
MAPK3	9078
PAPSS1	9039
AGTRAP	8987
MAP2K1	8960
QKI	8951
ITGA2B	8942
APBB1IP	8849
MARK3	8774
TLN1	8554
ARRB2	8517
AP3B1	8377
ITGB3	8367
FN1	8294
IQGAP1	8189
ATG7	8065
RAF1	7991
MAPK1	7520
VCL	7380
BCL2L11	7326
RAP1A	7319

Click HERE to show all gene set members

GeneID	Gene Rank
MAPK3	9078
PAPSS1	9039
AGTRAP	8987
MAP2K1	8960
QKI	8951
ITGA2B	8942
APBB1IP	8849
MARK3	8774
TLN1	8554
ARRB2	8517
AP3B1	8377
ITGB3	8367
FN1	8294
IQGAP1	8189
ATG7	8065
RAF1	7991
MAPK1	7520
VCL	7380
BCL2L11	7326
RAP1A	7319
KDM7A	6926
MAP2K2	6906
VWF	6607
YWHAB	6398
AGGF1	6284
NRAS	5411
FXR1	5385
CSK	5285
TRAK1	5063
FAM114A2	5026
KSR1	4113
SND1	3911
LMNA	3863
TRIM24	3824
KRAS	3760
KIAA1549	3668
RAP1B	3331
ARAF	2680
JAK2	2599
CLCN6	2278
ARRB1	2098
CAMK2G	1888
BRAF	1314
FAM131B	-831
CALM1	-2048
HRAS	-3335
KSR2	-3364
CNKSR2	-4481
AKAP9	-5065
CNKSR1	-6858
SRC	-9011
ZC3HAV1	-10197
MPRIP	-10647
TENT4A	-11171
PEBP1	-11270
CAMK2D	-11728
AGK	-12045

---

Intracellular signaling by second messengers

	573
set	Intracellular signaling by second messengers
setSize	273
pANOVA	3.71e-07
s.dist	0.179
p.adjustANOVA	5.56e-06

Top enriched genes

GeneID	Gene Rank
PPARG	9571
LAMTOR1	9450
PRKACA	9441
GRB2	9320
PHC2	9103
ADCY3	9101
AGO4	9094
RCOR1	9086
MAPK3	9078
VAPA	9073
PIK3CB	9065
TGFA	9031
KL	9019
PRKCD	9012
MKRN1	8864
HGF	8856
RRAGD	8850
FOXO3	8729
RAC1	8720
SNAI1	8669

Click HERE to show all gene set members

GeneID	Gene Rank
PPARG	9571
LAMTOR1	9450
PRKACA	9441
GRB2	9320
PHC2	9103
ADCY3	9101
AGO4	9094
RCOR1	9086
MAPK3	9078
VAPA	9073
PIK3CB	9065
TGFA	9031
KL	9019
PRKCD	9012
MKRN1	8864
HGF	8856
RRAGD	8850
FOXO3	8729
RAC1	8720
SNAI1	8669
RNF146	8622
PRKAR1A	8616
LAMTOR5	8611
RHOG	8544
PSMB7	8535
PTEN	8516
PSMD4	8498
PSME3	8331
IRS2	8323
PPP2CA	8308
EGF	8267
TRIM27	8257
PSMB5	8188
CAMKK2	8123
INSR	8103
MYD88	8091
WWP2	8046
PRKAR1B	8040
VAV1	8021
CHUK	7959
AKT1S1	7902
PSMD6	7881
PIK3AP1	7836
GSK3A	7811
CASP9	7784
PPP2CB	7769
PSMD9	7712
LAMTOR2	7704
LAMTOR3	7692
RHEB	7675
IER3	7557
MAPK1	7520
PSMD2	7470
IL1RAP	7349
PSMA1	7346
PSMD1	7283
PSMB3	7265
PSMA7	7174
PSMC1	7096
BAD	7002
PSMB6	6927
PPP2R5B	6870
PRKAR2B	6824
UBB	6737
PSMF1	6724
GSK3B	6720
PSMC6	6701
PSMD12	6537
PIP5K1B	6526
FOXO4	6493
AHCYL1	6475
CSNK2A2	6430
CAMKK1	6416
USP7	6410
RRAGA	6344
NEDD4	6330
PSMD11	6296
PRKAR2A	6265
PDPK1	6209
CSNK2A1	6207
PIP5K1A	6198
IRAK1	6159
GRK2	6141
PIK3CD	6096
HDAC7	6070
PSMD7	6017
PDGFRA	6002
PSMD13	5991
PPP2R5A	5985
PSMA6	5978
ITPR2	5919
PSMD8	5845
PDE1B	5822
MAF1	5804
GAB1	5723
AGO1	5660
HDAC2	5569
CBX8	5523
AREG	5494
PDGFA	5484
PSMA2	5433
PTPN11	5383
RAC2	5238
ADCY4	5226
MAPKAP1	5130
PIK3R2	5051
RRAGC	5033
HBEGF	4878
HDAC5	4761
HDAC3	4734
PIK3CA	4697
PSMD3	4693
PPP2R1A	4669
LAMTOR4	4487
CDKN1A	4438
SEM1	4436
UBC	4421
MDM2	4179
PSMB2	4103
CBX6	4091
NRG1	4018
CSNK2B	3987
JUN	3964
STRN	3758
FGF2	3660
PHLPP1	3657
AKT1	3656
RNF2	3573
PSMD5	3507
PIP5K1C	3436
PSMB1	3422
GATAD2A	3125
AGO2	3046
EGR1	2965
SLC38A9	2861
PSMD14	2703
PSMC2	2696
IL1RL1	2644
EPGN	2579
PSMB4	2552
MECOM	2503
PPP2R5D	2440
CBX4	2237
ATF2	2110
PSMC3	2018
EREG	1906
CAMK2G	1888
IRS1	1806
PSMD10	1646
XIAP	1478
PRKCA	1163
UBA52	1071
REST	945
RPS6KB2	652
HDAC1	394
IL33	392
AKT2	345
ATN1	305
MLST8	304
ADCY9	146
FRK	94
CD86	-71
TRAF6	-241
PPP2R1B	-246
NBEA	-347
ERBB3	-468
TNKS2	-512
PSMA4	-538
MBD3	-546
PPP2R5E	-627
RRAGB	-689
TSC2	-804
PSMC5	-948
AGO3	-1014
STUB1	-1093
CREB1	-1382
ADCY6	-1746
GATAD2B	-1780
RBBP4	-1907
NRG4	-1939
CALM1	-2048
PIP4K2A	-2339
SUZ12	-2444
ADCY2	-2874
FGFR4	-2892
MTA1	-2917
PSMB8	-3080
ADCY7	-3307
FRS2	-3430
CD19	-3769
FGF7	-3999
RING1	-4045
TNRC6B	-4558
CHD4	-4576
CBX2	-4693
PSMA3	-5314
FGFR1	-5335
PTENP1	-5342
SCMH1	-5553
TNRC6A	-5567
PSMB10	-5768
TRIB3	-5896
SALL4	-5965
PSME4	-6099
PSMA5	-6154
FOXO6	-6467
USP13	-6723
NR4A1	-6762
CD80	-6837
FGF23	-6840
KPNA2	-6845
RPS27A	-6894
TRAT1	-7043
MTA2	-7367
ITPR1	-7553
PSMA8	-7559
PIP4K2B	-7720
PHC1	-7816
PRKCE	-8024
PHC3	-8154
CDKN1B	-8305
ADCY5	-8315
PDGFB	-8575
FGF22	-8733
TNKS	-8839
ICOS	-8862
FGF9	-8873
PML	-8888
MTA3	-8918
SRC	-9011
FOXO1	-9173
CAMK4	-9185
ESR1	-9230
ESR2	-9236
PSMC4	-9306
EED	-9417
CHD3	-9466
KDM1A	-9476
RICTOR	-9593
PIK3R1	-9725
BMI1	-9787
CD28	-9858
EZH2	-9929
MTOR	-9948
ITPR3	-9955
PSME1	-10138
MIR25	-10321
PSME2	-10415
PLCG1	-10473
RPTOR	-10494
PRKX	-10527
OTUD3	-10628
TP53	-10936
THEM4	-10987
KIT	-11031
PSMB9	-11362
PIP4K2C	-11384
CNOT6L	-11389
PPP2R5C	-11413
PDGFRB	-11452
LCK	-11492
CAMK2D	-11728
TNRC6C	-11737
FGFR2	-11753
FYN	-11758
AKT3	-11804
PRKACB	-11857
PHLPP2	-11904
PRR5	-11948
MOV10	-11980
PIK3R3	-12037
RBBP7	-12085
ERBB2	-12281

---

RNA Polymerase II Transcription

	909
set	RNA Polymerase II Transcription
setSize	1204
pANOVA	3.79e-07
s.dist	-0.0869
p.adjustANOVA	5.61e-06

Top enriched genes

GeneID	Gene Rank
FASLG	-12319
TFDP2	-12315
RUNX3	-12312
ERBB2	-12281
NFATC2	-12236
YES1	-12143
GATA3	-12140
PTPN4	-12133
RAD1	-12131
ZNF599	-12123
AUTS2	-12091
RBBP7	-12085
ZNF3	-12084
ZNF287	-12042
PRKCQ	-12039
MDC1	-11988
MOV10	-11980
RPA1	-11962
WRN	-11954
FANCI	-11952

Click HERE to show all gene set members

GeneID	Gene Rank
FASLG	-12319.0
TFDP2	-12315.0
RUNX3	-12312.0
ERBB2	-12281.0
NFATC2	-12236.0
YES1	-12143.0
GATA3	-12140.0
PTPN4	-12133.0
RAD1	-12131.0
ZNF599	-12123.0
AUTS2	-12091.0
RBBP7	-12085.0
ZNF3	-12084.0
ZNF287	-12042.0
PRKCQ	-12039.0
MDC1	-11988.0
MOV10	-11980.0
RPA1	-11962.0
WRN	-11954.0
FANCI	-11952.0
PRR5	-11948.0
TP53RK	-11910.0
SMAD7	-11905.0
ZNF74	-11899.0
ZNF461	-11892.0
ZNF530	-11884.0
NUAK1	-11875.0
RORA	-11872.0
ANAPC1	-11870.0
DLL1	-11843.0
ZNF250	-11834.0
ZNF43	-11824.0
DGCR8	-11822.0
AKT3	-11804.0
ZNF70	-11798.0
ZNF620	-11789.0
STAT1	-11769.0
ZNF682	-11765.0
RFC5	-11754.0
ZNF33B	-11744.0
TNRC6C	-11737.0
CAMK2D	-11728.0
BRIP1	-11720.0
ZNF554	-11703.0
GLS	-11674.0
ZNF571	-11667.0
ZNF724	-11663.0
CCNE1	-11655.0
CCND2	-11649.0
ZNF500	-11640.0
SMARCD1	-11632.0
ZNF696	-11623.0
ZNF286A	-11614.0
DDB2	-11598.0
PARP1	-11586.0
ZNF607	-11570.0
ZNF570	-11563.0
ZNF496	-11561.0
ZNF549	-11552.0
ZNF707	-11550.0
SMAD3	-11541.0
ZNF736	-11535.0
ZNF568	-11528.0
RNPS1	-11511.0
RAD9A	-11491.0
DYRK2	-11483.0
FANCD2	-11476.0
ZNF337	-11474.0
FANCC	-11469.0
CUL1	-11467.0
KRBOX4	-11462.0
SUPT16H	-11458.0
ZNF136	-11442.0
PPP1R13B	-11439.0
ZNF517	-11424.0
ZNF569	-11423.0
PPP2R5C	-11413.0
ZNF660	-11407.0
JMY	-11399.0
CNOT6L	-11389.0
PIP4K2C	-11384.0
ATRIP	-11383.0
ZNF773	-11369.0
PSMB9	-11362.0
ZNF383	-11353.0
CDC23	-11349.0
ZNF30	-11348.0
MSH2	-11345.0
ZNF138	-11338.0
CENPJ	-11318.0
ZNF600	-11316.0
NR2C2AP	-11291.0
ZNF235	-11279.0
ZNF566	-11273.0
ZNF584	-11267.0
RUNX2	-11254.0
RAD51D	-11245.0
ZNF510	-11232.0
ZNF211	-11220.0
SSRP1	-11213.0
ZNF740	-11211.0
RNMT	-11210.0
ZNF75D	-11190.0
ZKSCAN8	-11169.0
WWOX	-11144.0
ZNF621	-11141.0
CDK4	-11138.0
ZNF184	-11134.0
ZNF133	-11132.0
ZNF324B	-11124.0
ZNF703	-11109.0
ANAPC5	-11108.0
ZNF77	-11103.0
ZNF519	-11102.0
ZNF19	-11100.0
ZNF432	-11099.0
ZFP30	-11090.0
COX11	-11085.0
PMAIP1	-11074.0
PCBP4	-11068.0
ZNF419	-11053.0
ZNF14	-11045.0
ZNF678	-11040.0
ZNF202	-11038.0
KIT	-11031.0
ITGAL	-11015.0
TP63	-11012.0
ITGA4	-11003.0
ZNF343	-11001.0
ZNF649	-10999.0
ZNF551	-10985.0
SKI	-10980.0
ZNF528	-10971.0
MECP2	-10955.0
BRD1	-10953.0
ZNF441	-10950.0
TP53	-10936.0
ZNF354C	-10918.0
PLXNA4	-10905.0
ZNF226	-10869.0
ATAD2	-10863.0
ZNF550	-10852.0
ATM	-10839.0
ZNF257	-10808.0
FBXO32	-10797.0
ZNF548	-10776.0
SRSF5	-10772.0
L3MBTL2	-10749.0
ZNF180	-10717.0
KMT2A	-10672.0
MAF	-10649.0
SIN3A	-10648.0
ZIK1	-10637.0
ZFP1	-10623.0
ZNF540	-10616.0
PRMT6	-10611.0
ZNF595	-10604.0
ZNF585B	-10585.0
DAXX	-10582.0
CTLA4	-10563.0
ZNF248	-10556.0
RFC3	-10515.0
RFC4	-10511.0
ZNF778	-10506.0
ZNF10	-10497.0
RPTOR	-10494.0
ZNF790	-10490.0
ZNF253	-10486.0
ZNF23	-10475.0
ZNF302	-10462.0
ZNF563	-10454.0
ZNF675	-10432.0
PSME2	-10415.0
ATR	-10403.0
ZFPM1	-10381.0
KAT2A	-10374.0
ZNF92	-10345.0
IFNG	-10320.0
ZNF544	-10316.0
AXIN1	-10310.0
NR3C2	-10304.0
ZNF680	-10298.0
ZNF446	-10293.0
LSM11	-10255.0
SMURF2	-10250.0
THOC1	-10245.0
ZNF529	-10241.0
RAD17	-10231.0
ZNF334	-10201.0
ABCA6	-10189.0
ZNF212	-10183.0
ZNF266	-10178.0
ZNF799	-10164.0
ZNF749	-10139.0
PSME1	-10138.0
ZC3H8	-10124.0
ZNF626	-10123.0
SMYD2	-10122.0
LRPPRC	-10120.0
RBL1	-10115.0
ZFP14	-10110.0
NR1D2	-10102.0
PERP	-10098.0
ZNF26	-10097.0
ZNF311	-10093.0
SRSF11	-10090.0
EPC1	-10064.0
ZNF420	-10042.0
WWP1	-10036.0
ZNF224	-10000.0
GPAM	-9993.0
ZNF596	-9991.0
ING5	-9987.0
MED15	-9976.0
MGA	-9961.0
NFYB	-9957.0
MTOR	-9948.0
TGIF2	-9946.0
EZH2	-9929.0
HEY2	-9918.0
ZNF704	-9866.0
SCO1	-9862.0
ZNF45	-9813.0
ZNF112	-9809.0
TXNIP	-9792.0
BMI1	-9787.0
ZNF684	-9785.0
ZNF483	-9777.0
ZNF473	-9775.0
NR2C1	-9766.0
ZNF689	-9765.0
ZNF664	-9754.0
ZNF583	-9745.0
ZNF737	-9744.0
LDB1	-9701.0
TCF7	-9694.0
ZFP90	-9691.0
MLLT3	-9688.0
ZNF227	-9671.0
IGFBP3	-9669.0
ZNF431	-9661.0
ZNF708	-9652.0
ZFP69	-9639.0
NCBP2	-9624.0
CPSF4	-9615.0
ZNF436	-9614.0
NPM1	-9596.0
RICTOR	-9593.0
CCNT1	-9570.0
ZNF41	-9557.0
ZNF324	-9551.0
TRPC3	-9546.0
ZNF263	-9538.0
ZNF484	-9505.0
NOP2	-9504.0
BRD2	-9501.0
ZNF157	-9485.0
ZSCAN25	-9474.0
ZNF625	-9473.0
CHD3	-9466.0
ZNF597	-9462.0
ZNF793	-9461.0
ZNF470	-9441.0
EED	-9417.0
ZNF506	-9375.0
ZNF614	-9373.0
ZNF354B	-9371.0
ZNF573	-9339.0
MED27	-9333.0
PSMC4	-9306.0
GATA2	-9305.0
ZNF727	-9280.0
ESR2	-9236.0
ESR1	-9230.0
ZNF582	-9222.0
TBP	-9220.0
CAMK4	-9185.0
FOXO1	-9173.0
ZNF699	-9166.0
ZNF160	-9158.0
CBX5	-9139.0
INTS4	-9127.0
MAGOHB	-9110.0
ZNF767P	-9099.0
ZNF782	-9087.0
SESN1	-9083.0
RPAP2	-9071.0
SMARCC1	-9046.0
ZNF738	-9015.0
SRC	-9011.0
RPA3	-9003.0
ZNF677	-8997.0
ZNF17	-8990.0
ZNF433	-8940.0
TRIM33	-8937.0
ZNF606	-8924.0
PRDM1	-8919.0
ZNF485	-8908.0
ZNF79	-8907.0
ZNF619	-8897.0
PRMT1	-8894.0
PML	-8888.0
ZNF721	-8881.0
SIRT3	-8860.0
MNAT1	-8852.0
ZNF317	-8848.0
ZNF440	-8835.0
ZNF439	-8834.0
ZNF792	-8833.0
ZNF567	-8797.0
ICE2	-8794.0
ZNF416	-8770.0
EHMT1	-8729.0
ZNF140	-8719.0
ZNF141	-8708.0
ZNF717	-8704.0
AIFM2	-8680.0
NR2C2	-8678.0
TGIF1	-8667.0
MED10	-8659.0
FOXP3	-8628.0
NR1D1	-8603.0
ZNF709	-8595.0
TAF1	-8536.0
CDK13	-8535.0
ZNF559	-8520.0
EHMT2	-8517.0
ZNF331	-8509.0
SNAPC3	-8496.0
SRSF7	-8467.0
ZNF681	-8462.0
MAPKAPK5	-8452.0
L3MBTL1	-8405.0
UPF3B	-8397.0
ZNF234	-8374.0
ICE1	-8366.0
HDAC6	-8348.0
ZNF300	-8316.0
E2F5	-8308.0
SKP2	-8307.0
CDKN1B	-8305.0
SMAD4	-8273.0
RORC	-8272.0
MEN1	-8265.0
MEAF6	-8251.0
ZNF274	-8227.0
GLI3	-8180.0
ZFP37	-8177.0
PHC3	-8154.0
ZNF665	-8087.0
PRKAB2	-8083.0
FIP1L1	-8076.0
ZNF720	-8047.0
ZKSCAN3	-8032.0
ZNF641	-8025.0
INTS7	-8014.0
ZNF688	-8012.0
BBC3	-7987.0
ZNF521	-7954.0
THOC3	-7944.0
CDC7	-7896.0
ZNF726	-7894.0
MRE11	-7888.0
TAF4B	-7865.0
TNFRSF18	-7833.0
PHC1	-7816.0
ZNF702P	-7783.0
HES1	-7731.0
ZNF175	-7723.0
ERCC3	-7721.0
PIP4K2B	-7720.0
ZNF320	-7709.0
ZNF273	-7685.0
ZNF791	-7659.0
ZNF75A	-7592.0
ZNF2	-7584.0
WDR33	-7583.0
GLS2	-7572.0
ZNF585A	-7564.0
PSMA8	-7559.0
ZNF671	-7555.0
ZNF264	-7539.0
RBM8A	-7527.0
RGCC	-7511.0
RBM14	-7496.0
RAD50	-7482.0
YWHAQ	-7471.0
MED24	-7462.0
ACTL6A	-7411.0
TAF6	-7402.0
NABP2	-7383.0
ZNF195	-7382.0
YAF2	-7372.0
MTA2	-7367.0
ZNF771	-7328.0
IL2RA	-7301.0
ANAPC2	-7284.0
RBL2	-7257.0
LEF1	-7246.0
BRPF1	-7223.0
ZNF12	-7194.0
ZNF577	-7167.0
ZNF382	-7116.0
ZNF777	-7081.0
ZNF425	-6990.0
ZNF785	-6950.0
ZNF786	-6944.0
ZNF268	-6940.0
COX19	-6928.0
RPS27A	-6894.0
MLH1	-6878.0
ZNF418	-6875.0
CCND1	-6847.0
ZNF711	-6820.0
ANAPC4	-6780.0
GAMT	-6775.0
NR4A1	-6762.0
TCF3	-6757.0
SUPT5H	-6744.0
ZNF33A	-6730.0
ZNF223	-6729.0
FBXW7	-6709.0
MED23	-6699.0
GAD2	-6686.0
ZNF764	-6661.0
INTS9	-6655.0
ZNF415	-6651.0
PIDD1	-6606.0
ZKSCAN7	-6571.0
ZFP28	-6554.0
TAF15	-6541.0
RHNO1	-6524.0
H2BU1	-6519.0
BRPF3	-6480.0
ZNF135	-6472.0
FOXO6	-6467.0
TJP1	-6461.0
ZNF616	-6426.0
SUPT6H	-6413.0
RPA2	-6397.0
ZNF480	-6393.0
CSTF2	-6390.0
CDK6	-6379.0
THRA	-6373.0
DDX39A	-6345.0
TFAP2E	-6342.0
AGRP	-6298.0
NELFCD	-6291.0
ZNF691	-6276.0
ZNF442	-6252.0
CSTF2T	-6211.0
WWTR1	-6206.0
SYMPK	-6205.0
ZNF610	-6187.0
KMT2E	-6165.0
RNF34	-6162.0
CSTF1	-6157.0
PSMA5	-6154.0
ZNF208	-6140.0
ZNF706	-6138.0
COX18	-6129.0
PSME4	-6099.0
PPARD	-6092.0
ZNF557	-6048.0
PCNA	-6038.0
CDC16	-6037.0
ZNF169	-6034.0
TAF2	-5999.0
ZNF543	-5993.0
ZNF398	-5917.0
E2F7	-5910.0
NOC2L	-5908.0
ZNF493	-5903.0
NCBP1	-5866.0
ZNF662	-5826.0
FYTTD1	-5824.0
PSMB10	-5768.0
SRSF2	-5743.0
ZNF718	-5691.0
ZNF713	-5662.0
SETD1A	-5656.0
ZNF101	-5620.0
ZNF761	-5594.0
ZNF71	-5593.0
PMS2	-5588.0
ZNF154	-5579.0
TNRC6A	-5567.0
ZNF34	-5557.0
SCMH1	-5553.0
KRBA1	-5549.0
ARID1B	-5542.0
ZFP69B	-5536.0
MED30	-5533.0
ZNF658	-5480.0
ZNF514	-5474.0
ZNF25	-5449.0
TNKS1BP1	-5439.0
TCF7L2	-5419.0
BLK	-5390.0
ZNF99	-5340.0
ZNF589	-5337.0
PSMA3	-5314.0
CDKN2A	-5302.0
PHAX	-5288.0
ZNF37A	-5273.0
ANAPC7	-5259.0
RABGGTB	-5240.0
ZNF615	-5239.0
ZKSCAN4	-5210.0
BTG1	-5204.0
NOTCH4	-5200.0
ZNF547	-5191.0
CCNT2	-5173.0
ZNF443	-5161.0
NR4A3	-5131.0
PPARGC1B	-5117.0
SRRT	-5101.0
SRRM1	-5091.0
ANAPC10	-5074.0
ZNF285	-5070.0
COX20	-5036.0
CDK2	-5018.0
ZNF155	-5007.0
ZNF124	-5001.0
ZNF417	-4959.0
E2F6	-4946.0
SOCS4	-4914.0
TRIM28	-4905.0
ZNF430	-4872.0
SRSF6	-4840.0
RARG	-4816.0
TP73	-4805.0
MAMLD1	-4791.0
ZNF700	-4784.0
ZNF546	-4775.0
BLM	-4764.0
ZNF611	-4733.0
CBX2	-4693.0
RBBP8	-4692.0
DHX38	-4681.0
ZNF492	-4637.0
CHD4	-4576.0
TNRC6B	-4558.0
RPRD2	-4553.0
ZNF564	-4521.0
ZNF460	-4514.0
TAF5	-4458.0
ZNF197	-4453.0
ZNF426	-4438.0
CHEK2	-4375.0
U2AF1L4	-4338.0
SMARCE1	-4337.0
ZNF561	-4324.0
CNOT1	-4305.0
SCO2	-4299.0
ZNF692	-4253.0
NR1I2	-4247.0
DDX39B	-4245.0
SIRT1	-4217.0
SIN3B	-4201.0
PCGF2	-4179.0
SMARCC2	-4163.0
MED1	-4082.0
POLR2D	-4058.0
RMI2	-4057.0
RING1	-4045.0
ZNF233	-4022.0
ZNF486	-3995.0
CDK9	-3988.0
ARID2	-3959.0
YEATS4	-3942.0
CNOT7	-3875.0
ZNF215	-3859.0
NELFA	-3858.0
SMARCB1	-3855.0
PRELID3A	-3846.0
SNAPC5	-3821.0
CPSF1	-3801.0
NUDT21	-3729.0
ZNF676	-3634.0
ZNF701	-3602.0
SESN3	-3595.0
BCL2L14	-3588.0
GPX2	-3560.0
ZSCAN32	-3495.0
CASP10	-3491.0
TOPBP1	-3486.0
ZNF556	-3483.0
ZNF655	-3451.0
BARD1	-3441.0
NR1H3	-3418.0
PCGF5	-3397.0
ZNF350	-3381.0
PAX5	-3344.0
ZNF624	-3331.0
ZNF714	-3329.0
UXT	-3286.0
PIN1	-3272.0
RXRB	-3221.0
POLR2A	-3105.0
PSMB8	-3080.0
ZNF221	-3044.0
ZFP2	-3007.0
GTF2H1	-2929.0
ZNF670	-2911.0
GTF2H4	-2906.0
TAF11	-2897.0
DNA2	-2882.0
CASP6	-2858.0
POLR2H	-2817.0
CTSV	-2816.0
HIVEP3	-2800.0
PCF11	-2785.0
PLK2	-2772.0
RAD51	-2740.0
ZNF555	-2734.0
SMARCA2	-2716.0
CNOT10	-2690.0
ZNF490	-2614.0
TAF9B	-2602.0
TTC5	-2589.0
SMURF1	-2584.0
ZNF18	-2547.0
POLR2B	-2536.0
CHEK1	-2534.0
ZNF605	-2515.0
CASP2	-2478.0
ZNF772	-2476.0
RABGGTA	-2455.0
SUZ12	-2444.0
SNRPB	-2440.0
SNRPF	-2426.0
KAT2B	-2393.0
SRSF3	-2360.0
OCLN	-2358.0
PIP4K2A	-2339.0
ZNF839	-2260.0
FZR1	-2253.0
GTF2H3	-2247.0
ANAPC16	-2165.0
CNOT2	-2108.0
TSC1	-2097.0
ZC3H11A	-2087.0
CALM1	-2048.0
CDK8	-1997.0
INTS2	-1975.0
ZNF860	-1966.0
RBBP4	-1907.0
PHF20	-1870.0
KCTD1	-1854.0
TAF3	-1820.0
HSPD1	-1809.0
RELA	-1807.0
POLR2K	-1792.0
GATAD2B	-1780.0
RFFL	-1730.0
TAF4	-1726.0
NR2F1	-1708.0
ZNF468	-1707.0
ZNF669	-1696.0
ZNF28	-1676.0
DDIT4	-1660.0
NR4A2	-1625.0
EXO1	-1572.0
CHTOP	-1563.0
COX14	-1508.0
BGLAP	-1498.0
CREB1	-1382.0
CDK12	-1370.0
ZNF750	-1367.0
CNOT4	-1306.0
CYCS	-1282.0
SETD9	-1269.0
TCF12	-1268.0
H2AZ2	-1266.0
H19	-1263.0
MDM4	-1218.0
CDK5R1	-1166.0
STUB1	-1093.0
INTS5	-1077.0
ZNF627	-1060.0
AGO3	-1014.0
ZNF565	-953.0
TCEA1	-951.0
PSMC5	-948.0
GPS2	-914.0
ZNF562	-896.0
MED6	-888.0
SNAPC4	-826.0
TSC2	-804.0
MOBP	-750.0
UBE2I	-746.0
PCGF6	-708.0
RRAGB	-689.0
CDC27	-659.0
SKIL	-606.0
ZNF558	-592.0
NPPA	-569.0
MBD3	-546.0
PSMA4	-538.0
PABPN1	-526.0
ZNF716	-511.0
MAML2	-476.0
MEF2C	-319.0
PPP2R1B	-246.0
MED14	-205.0
RRM2	-188.0
ZNF587	-183.0
ZNF200	-170.0
HUS1	-131.0
ZNF222	-72.0
BRD7	-36.0
ZNF347	-33.0
KLF4	11.0
MT-CO2	35.0
MT-CO3	47.0
ELL3	65.0
KMT2C	71.0
LEO1	84.0
WDR61	87.0
APOE	103.0
WDR5	123.0
MED7	178.0
COX16	214.0
ABL1	229.0
TRIAP1	238.0
TCF7L1	265.0
INTS12	267.0
MLST8	304.0
POLR2I	316.0
CSTF3	334.0
AKT2	345.0
ZNF100	353.0
ZNF776	366.0
NELFB	385.0
HDAC1	394.0
PPP1R13L	418.0
CCNB1	460.0
PLAGL1	465.0
CSF1R	487.0
YY1	529.0
MYB	555.0
COX7C	558.0
CCNA1	575.0
TEAD2	599.0
NR3C1	600.0
SNRPE	610.0
BANP	649.0
SNAPC1	655.0
MT-CO1	675.0
CLDN5	702.0
COX6C	721.0
SETD1B	751.0
KAT6A	764.0
INTS1	766.0
CCNH	783.0
PPARA	865.0
U2AF1	882.0
THOC2	906.0
AURKB	959.0
MAGOH	995.0
RBBP5	1009.0
ZNF429	1060.0
UBA52	1071.0
RPRD1B	1159.0
KMT2B	1204.0
GCK	1242.0
TAF9	1249.0
PRKAB1	1302.0
ZNF394	1327.0
HDAC9	1347.0
PRKAA1	1352.0
KAT5	1361.0
AFF4	1390.0
ITCH	1394.0
ZKSCAN5	1418.0
CDK1	1480.0
MED31	1486.0
POLR2C	1531.0
SFN	1557.0
THRB	1600.0
POU2F1	1611.0
SNRPD3	1613.0
ATXN3	1623.0
SNRPG	1630.0
PSMD10	1646.0
ELF1	1662.0
CCNA2	1676.0
KCTD15	1753.0
TNFRSF10A	1785.0
TPX2	1833.0
CAV1	1856.0
CCNC	1883.0
CAMK2G	1888.0
ZNF658B	1910.0
NR1I3	1915.0
ZNF613	1941.0
PRKAG2	1942.0
TAF7	1986.0
PSMC3	2018.0
MED12	2042.0
PVALB	2049.0
CNOT11	2103.0
ATF2	2110.0
CBFB	2152.0
OPRM1	2186.0
ZKSCAN1	2205.0
CBX4	2237.0
STK11	2241.0
NBN	2243.0
CHM	2291.0
HDAC10	2302.0
GTF2E1	2363.0
MYC	2367.0
SRSF1	2377.0
MYBL2	2543.0
PSMB4	2552.0
SARNP	2564.0
MED13	2566.0
ELF2	2628.0
DEK	2655.0
PSMC2	2696.0
ZNF586	2702.0
PSMD14	2703.0
GTF2A1	2744.0
SLU7	2754.0
NRBP1	2851.0
SLC38A9	2861.0
BTG2	2864.0
E2F8	2873.0
RNU1-1	2891.5
ZNF471	2905.0
CCNK	2936.0
VENTX	2938.0
POMC	2971.0
SUPT4H1	3005.0
MED17	3008.0
CDC26	3013.0
ZNF770	3021.0
RNGTT	3030.0
GTF2H2	3035.0
AGO2	3046.0
RAD9B	3101.0
GATAD2A	3125.0
HDAC8	3141.0
THOC6	3226.0
KMT2D	3244.0
MED4	3271.0
HTT	3299.0
CTR9	3381.0
ZNF445	3386.0
CPSF7	3398.0
PSMB1	3422.0
CREBBP	3460.0
PRDX2	3467.0
AURKA	3503.0
NFYA	3506.0
PSMD5	3507.0
PAF1	3523.0
ERCC2	3545.0
ZNF189	3549.0
RNF2	3573.0
PRMT5	3578.0
POLR2G	3581.0
SURF1	3585.0
ZNF205	3595.0
GTF2B	3599.0
RTF1	3600.0
SESN2	3606.0
SSU72	3617.0
U2AF2	3622.0
TAF8	3643.0
AKT1	3656.0
FAS	3710.0
ZNF668	3732.0
KRAS	3760.0
ZNF667	3775.0
SRSF4	3801.0
DPY30	3810.0
TMEM219	3875.0
GTF2H5	3879.0
ZNF354A	3918.0
NELFE	3922.0
PPARGC1A	3934.0
MAPK11	3955.0
JUN	3964.0
ZNF747	3974.0
CSNK2B	3987.0
ZNF333	4038.0
RBX1	4039.0
BIRC5	4082.0
CASP1	4086.0
CBX6	4091.0
PSMB2	4103.0
MDM2	4179.0
POU2F2	4246.0
COX4I1	4252.0
MAX	4285.0
INTS10	4333.0
SKP1	4349.0
ING2	4405.0
UBC	4421.0
KCTD6	4434.0
SEM1	4436.0
CDKN1A	4438.0
MED26	4456.0
SOD2	4458.0
TACO1	4468.0
LAMTOR4	4487.0
COX7B	4554.0
CTSL	4583.0
TBL1XR1	4627.0
RPRD1A	4632.0
SGK1	4642.0
POLR2F	4646.0
PPP2R1A	4669.0
NDRG1	4678.0
PSMD3	4693.0
ZNF552	4708.0
NOTCH1	4733.0
HDAC3	4734.0
ZNF774	4747.0
HDAC5	4761.0
SMARCA4	4789.0
HDAC11	4790.0
CNOT6	4799.0
UBE2S	4810.0
ZNF20	4817.0
DLX6	4879.0
CBX3	4882.0
ARID1A	4896.0
AR	4913.0
DDIT3	4938.0
SMAD2	4939.0
CCNG1	4943.0
ZNF282	5019.0
CDC25C	5024.0
RRAGC	5033.0
H2AC20	5039.0
RFC2	5040.0
GTF2F1	5042.0
ELL	5057.0
SNAPC2	5072.0
CTSK	5077.0
CDC73	5093.0
NR2F6	5106.0
ZNF775	5121.0
MAPKAP1	5130.0
COX6A1	5167.0
UBE2C	5168.0
CCNE2	5178.0
TGFB1	5201.0
GPRIN1	5211.0
SNW1	5255.0
NOTCH2	5276.0
CASC3	5289.0
CDK7	5292.0
CRADD	5317.0
MED16	5319.0
POLR2L	5362.0
CNOT3	5371.0
PTPN11	5383.0
TWIST2	5405.0
SLBP	5410.0
PSMA2	5433.0
MAML1	5447.0
H2BC15	5458.0
H2BC9	5461.0
ALYREF	5493.0
GTF2F2	5503.0
CBX8	5523.0
USP9X	5542.0
HDAC2	5569.0
PRKAG1	5582.0
RYBP	5586.0
TP53BP2	5594.0
EAF1	5607.0
PBRM1	5635.0
AGO1	5660.0
G6PC	5665.0
YWHAZ	5687.0
INTS6	5751.0
COX6B1	5755.0
PF4	5777.0
PTPN1	5797.0
RNF111	5821.0
KDM5B	5826.0
PSMD8	5845.0
GTF2E2	5856.0
PRELID1	5864.0
HIPK1	5901.0
ZNF385A	5929.0
IWS1	5941.0
THBS1	5946.0
ESRRA	5973.0
PSMA6	5978.0
NCOR1	5979.0
ASH2L	5989.0
PSMD13	5991.0
BAX	5996.0
PSMD7	6017.0
ZNF213	6031.0
HDAC7	6070.0
BID	6075.0
STEAP3	6076.0
H2AZ1	6126.0
IRAK1	6159.0
FOS	6179.0
CSNK2A1	6207.0
EP300	6208.0
PDPK1	6209.0
HIPK2	6215.0
COX5A	6238.0
GPI	6246.0
ANAPC11	6249.0
BRCA1	6273.0
MED25	6290.0
CTDP1	6295.0
PSMD11	6296.0
TIGAR	6306.0
INTS3	6311.0
GP1BA	6320.0
COX5B	6328.0
RRAGA	6344.0
RARA	6365.0
NFKB1	6367.0
THOC7	6391.0
E2F4	6395.0
YWHAB	6398.0
USP7	6410.0
CSNK2A2	6430.0
LSM10	6432.0
CTNNB1	6463.0
CITED2	6467.0
E2F1	6473.0
FOXO4	6493.0
PSMD12	6537.0
CPSF3	6549.0
TP53INP1	6554.0
NDUFA4	6586.0
SATB2	6611.0
SREBF1	6642.0
TAL1	6644.0
CLP1	6691.0
PSMC6	6701.0
COX8A	6712.0
GSK3B	6720.0
PSMF1	6724.0
EAF2	6729.0
UBB	6737.0
CCNG2	6752.0
PLK3	6767.0
POLR2J	6769.0
H3C15	6780.5
ZNF230	6798.0
CDC40	6836.0
RRM2B	6849.0
MED20	6851.0
UBE2E1	6853.0
JUNB	6889.0
PSMB6	6927.0
ZNF710	6928.0
SUMO1	6973.0
SMARCD2	6976.0
RMI1	6994.0
PRKCB	7056.0
PSMC1	7096.0
PRDX1	7104.0
PSMA7	7174.0
TAF10	7190.0
GTF2A2	7207.0
ZNF267	7214.0
PAPOLA	7250.0
PSMB3	7265.0
PSMD1	7283.0
BCL2L11	7326.0
TAF13	7332.0
THOC5	7343.0
PSMA1	7346.0
ELOA	7366.0
ZNF143	7367.0
EIF4A3	7369.0
POLDIP3	7378.0
VEGFA	7389.0
PSMD2	7470.0
ZFHX3	7472.0
H2BC17	7502.0
CCND3	7510.0
NR1H2	7512.0
RXRA	7513.0
MAPK1	7520.0
SRSF9	7532.0
H2BC4	7549.0
SERPINE1	7580.0
ELOB	7586.0
RUNX1	7591.0
CITED4	7593.0
MED8	7625.0
ELOC	7637.0
POLR2E	7660.0
RHEB	7675.0
ZNF746	7689.0
LAMTOR3	7692.0
ITGA5	7699.0
LAMTOR2	7704.0
PSMD9	7712.0
MYL9	7719.0
NFYC	7726.0
PPP2CB	7769.0
COX7A2L	7808.0
SMAD6	7853.0
PPM1D	7879.0
PSMD6	7881.0
CPSF2	7886.0
MLLT1	7898.0
ELL2	7901.0
TOP3A	7914.0
NCOR2	7948.0
NEDD4L	7972.0
TNFRSF10C	7974.0
TBL1X	7984.0
NOTCH3	8004.0
H2AC6	8070.0
H2BC11	8076.0
TAF12	8078.0
KMT5A	8105.0
CEBPB	8108.0
NABP1	8109.0
H2BC5	8163.0
PSMB5	8188.0
INTS8	8193.0
NRBF2	8203.0
LBR	8224.0
VDR	8258.0
PPM1A	8296.0
TXNRD1	8303.0
PPP2CA	8308.0
CNOT8	8312.0
SP1	8315.0
PSME3	8331.0
LMO2	8335.0
TXN	8414.0
TNFRSF10B	8435.0
SMAD1	8465.0
PSMD4	8498.0
TFDP1	8500.0
PTEN	8516.0
GATA1	8529.0
PSMB7	8535.0
LAMTOR5	8611.0
PRDX5	8612.0
ARID3A	8617.0
LGALS3	8619.0
YWHAH	8621.0
SMARCD3	8637.0
RB1	8649.0
NR6A1	8651.0
JAG1	8661.0
CDK5	8663.0
UBE2D3	8710.0
FOXO3	8729.0
RBPJ	8744.0
H3-3A	8754.0
CDKN2B	8797.0
RRAGD	8850.0
SPI1	8907.0
FKBP5	8936.0
ITGA2B	8942.0
MAML3	8965.0
YWHAE	9009.0
MAP2K6	9010.0
TGFA	9031.0
ANAPC15	9035.0
G6PD	9045.0
TP53I3	9050.0
PINK1	9054.0
HDAC4	9057.0
APAF1	9072.0
MAPK3	9078.0
ZNF697	9092.0
AGO4	9094.0
PHC2	9103.0
CARM1	9122.0
UBE2D1	9125.0
CAT	9137.0
SLC2A3	9144.0
TNFRSF10D	9167.0
H2BC12	9178.0
MAPK14	9219.0
RETN	9241.0
GSR	9256.0
GADD45A	9260.0
BCL6	9299.0
YWHAG	9310.0
BNIP3L	9327.0
H2BC21	9368.0
NLRC4	9406.0
H2AJ	9418.0
PRKACA	9441.0
LAMTOR1	9450.0
NFE2	9490.0
SOCS3	9526.0
CR1	9545.0
PPARG	9571.0

---

C-type lectin receptors (CLRs)

	120
set	C-type lectin receptors (CLRs)
setSize	129
pANOVA	4.08e-07
s.dist	0.258
p.adjustANOVA	5.92e-06

Top enriched genes

GeneID	Gene Rank
PRKACA	9441
CLEC4D	9154
UBE2D1	9125
SYK	9087
PRKCD	9012
PYCARD	8734
CDC34	8728
PSMB7	8535
PSMD4	8498
CLEC4A	8344
PSME3	8331
PAK1	8252
CLEC4E	8250
PPP3R1	8240
PAK2	8226
PSMB5	8188
FCER1G	8143
RAF1	7991
CHUK	7959
ICAM3	7916

Click HERE to show all gene set members

GeneID	Gene Rank
PRKACA	9441
CLEC4D	9154
UBE2D1	9125
SYK	9087
PRKCD	9012
PYCARD	8734
CDC34	8728
PSMB7	8535
PSMD4	8498
CLEC4A	8344
PSME3	8331
PAK1	8252
CLEC4E	8250
PPP3R1	8240
PAK2	8226
PSMB5	8188
FCER1G	8143
RAF1	7991
CHUK	7959
ICAM3	7916
PSMD6	7881
UBA3	7776
LYN	7728
PSMD9	7712
UBE2M	7590
PSMD2	7470
PSMA1	7346
PSMD1	7283
PSMB3	7265
PSMA7	7174
PSMC1	7096
TAB2	7070
PPP3CB	6998
PSMB6	6927
NFKBIA	6835
UBB	6737
PSMF1	6724
PSMC6	6701
CARD9	6650
MUC1	6589
PSMD12	6537
CLEC6A	6509
AHCYL1	6475
NFKB1	6367
PPP3CA	6327
PSMD11	6296
FBXW11	6282
PDPK1	6209
EP300	6208
PSMD7	6017
PSMD13	5991
PSMA6	5978
BCL10	5931
ITPR2	5919
PSMD8	5845
TAB1	5711
UBE2V1	5681
CLEC7A	5515
IKBKG	5434
PSMA2	5433
NRAS	5411
PLCG2	5103
IL1B	4830
UBE2D2	4721
PSMD3	4693
SEM1	4436
UBC	4421
SKP1	4349
PSMB2	4103
RELB	3767
KRAS	3760
PSMD5	3507
CREBBP	3460
PSMB1	3422
TAB3	3165
PSMD14	2703
PSMC2	2696
PSMB4	2552
MAP3K7	2453
PSMC3	2018
UBE2N	1951
PSMD10	1646
UBA52	1071
TRAF6	-241
PSMA4	-538
NFKB2	-865
PSMC5	-948
RELA	-1807
CALM1	-2048
MUCL1	-2297
MUC4	-2624
MUC6	-3012
PSMB8	-3080
MUC16	-3285
HRAS	-3335
PAK3	-4194
MUC5B	-4618
BTRC	-4932
IKBKB	-5290
PSMA3	-5314
CLEC10A	-5371
PSMB10	-5768
MUC20	-5791
PSME4	-6099
PSMA5	-6154
RPS27A	-6894
ITPR1	-7553
PSMA8	-7559
SRC	-9011
CD209	-9237
PSMC4	-9306
NFATC1	-9315
ITPR3	-9955
PSME1	-10138
PSME2	-10415
MALT1	-10701
MUC12	-10883
PSMB9	-11362
CASP8	-11463
CUL1	-11467
MAP3K14	-11478
RPS6KA5	-11616
FYN	-11758
PRKACB	-11857
CLEC4C	-11862
ICAM2	-11994
CARD11	-12035
NFATC3	-12139
NFATC2	-12236

---

Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

	1006
set	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
setSize	124
pANOVA	4.08e-07
s.dist	0.263
p.adjustANOVA	5.92e-06

Top enriched genes

GeneID	Gene Rank
ETFA	8614
NDUFB3	8536
SDHC	8512
NDUFB9	8336
NDUFAF1	8295
UQCRH	8187
ETFDH	8086
UQCRC1	7829
COX7A2L	7808
ETFB	7772
NDUFB1	7664
ATP5PB	7663
ATP5PD	7656
SDHB	7568
NDUFAF3	7092
SDHD	7024
UQCR11	7005
TIMMDC1	6842
COX8A	6712
ATP5F1C	6627

Click HERE to show all gene set members

GeneID	Gene Rank
ETFA	8614
NDUFB3	8536
SDHC	8512
NDUFB9	8336
NDUFAF1	8295
UQCRH	8187
ETFDH	8086
UQCRC1	7829
COX7A2L	7808
ETFB	7772
NDUFB1	7664
ATP5PB	7663
ATP5PD	7656
SDHB	7568
NDUFAF3	7092
SDHD	7024
UQCR11	7005
TIMMDC1	6842
COX8A	6712
ATP5F1C	6627
ATP5MF	6615
NDUFA4	6586
ATP5F1A	6536
ATP5F1B	6524
ATP5PF	6488
NDUFS1	6345
COX5B	6328
UQCRFS1	6294
ATP5F1E	6259
NDUFS5	6252
COX5A	6238
NDUFC2	6199
NDUFS2	6169
NDUFA6	6108
ATP5MC3	6010
NDUFB10	5889
UQCRC2	5885
NDUFAB1	5846
NDUFA1	5827
COX6B1	5755
NDUFA7	5698
ATP5MG	5608
NDUFC1	5436
NDUFV3	5191
COX6A1	5167
NDUFA2	5018
ECSIT	4997
NDUFA8	4885
ATP5PO	4868
NDUFB4	4594
COX7B	4554
TACO1	4468
UQCR10	4424
NDUFV2	4345
NDUFA13	4294
NDUFB6	4265
NDUFS6	4258
COX4I1	4252
COQ10B	4065
NDUFS4	4035
NDUFB5	3970
UQCRB	3916
SURF1	3585
CYC1	3139
ATP5MC2	3017
ATP5F1D	3007
UQCRQ	2981
NDUFAF7	2695
ATP5ME	2673
NDUFB7	2332
NDUFAF2	2174
NDUFS7	2129
NDUFA11	1471
NDUFB11	1201
NDUFB8	974
UCP2	969
NDUFS3	929
MT-ND4	830
COX6C	721
MT-CO1	675
COX7C	558
NDUFA3	528
MT-ND6	453
COX16	214
NDUFS8	80
MT-CO3	47
MT-CO2	35
ACAD9	-904
CYCS	-1282
COX14	-1508
NDUFA12	-1763
MT-ATP6	-2106
MT-ND5	-2218
NDUFAF6	-2303
MT-CYB	-2314
MT-ATP8	-2961
MT-ND3	-3687
MT-ND1	-3693
SCO2	-4299
SLC25A27	-4389
NDUFB2	-4470
SLC25A14	-4687
NDUFA5	-4736
COX20	-5036
SDHA	-5523
COX18	-6129
MT-ND2	-6660
COX19	-6928
NDUFA10	-7022
DMAC2L	-7416
ATP5MC1	-7598
TMEM126B	-8426
NDUFA9	-8944
NDUFAF5	-9710
SCO1	-9862
NDUFAF4	-9891
PM20D1	-10109
LRPPRC	-10120
UCP3	-10264
TRAP1	-10800
COX11	-11085
COQ10A	-11185
NDUFV1	-11489
NUBPL	-11590

---

VEGFA-VEGFR2 Pathway

	1307
set	VEGFA-VEGFR2 Pathway
setSize	92
pANOVA	4.79e-07
s.dist	0.304
p.adjustANOVA	6.88e-06

Top enriched genes

GeneID	Gene Rank
WASF1	9568
PRKACA	9441
NCF4	9365
CYFIP1	9270
CTNNA1	9237
MAPK14	9219
NCF2	9209
PIK3CB	9065
PRKCD	9012
CYBB	9000
CRK	8941
RAC1	8720
CDH5	8691
WASF2	8373
ITGB3	8367
MAPKAPK3	8255
PAK1	8252
PAK2	8226
RHOA	8218
VAV1	8021

Click HERE to show all gene set members

GeneID	Gene Rank
WASF1	9568
PRKACA	9441
NCF4	9365
CYFIP1	9270
CTNNA1	9237
MAPK14	9219
NCF2	9209
PIK3CB	9065
PRKCD	9012
CYBB	9000
CRK	8941
RAC1	8720
CDH5	8691
WASF2	8373
ITGB3	8367
MAPKAPK3	8255
PAK1	8252
PAK2	8226
RHOA	8218
VAV1	8021
PTK2B	8010
SPHK1	7724
NCKAP1	7562
CDC42	7539
NCKAP1L	7516
ROCK1	7445
NCF1	7433
DOCK1	7413
VEGFA	7389
ABI1	7154
BRK1	7085
PRKCB	7056
CYBA	6952
WASF3	6915
AHCYL1	6475
CTNNB1	6463
PXN	6332
ELMO1	6324
PDPK1	6209
SHB	6181
ROCK2	6151
ITGAV	6133
ITPR2	5919
NRAS	5411
MAPKAP1	5130
PIK3R2	5051
NCK2	5007
VAV3	4974
PIK3CA	4697
ELMO2	4507
PTK2	4506
SHC2	4499
MAPKAPK2	4176
MAPK11	3955
KRAS	3760
MAPK13	3704
AKT1	3656
RASA1	2134
CAV1	1856
HSPB1	1738
HSP90AA1	1348
PRKCA	1163
AKT2	345
MLST8	304
BAIAP2	-179
MAPK12	-946
NOS3	-1718
CALM1	-2048
HRAS	-3335
VAV2	-4073
PAK3	-4194
JUP	-5541
TRIB3	-5896
ITPR1	-7553
CTNND1	-8519
SRC	-9011
RICTOR	-9593
PIK3R1	-9725
MTOR	-9948
ITPR3	-9955
CYFIP2	-10387
PLCG1	-10473
ABI2	-10893
THEM4	-10987
NCK1	-11488
PRKCZ	-11508
FYN	-11758
AKT3	-11804
PRKACB	-11857
PRR5	-11948
AXL	-12293
SH2D2A	-12317

---

MAP kinase activation

	610
set	MAP kinase activation
setSize	63
pANOVA	5.02e-07
s.dist	0.366
p.adjustANOVA	7.14e-06

Top enriched genes

GeneID	Gene Rank
DUSP3	9324
MAPK14	9219
MAPK3	9078
MAP2K6	9010
MAP2K1	8960
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
MEF2A	8030
CHUK	7959
RPS6KA1	7800
PPP2CB	7769
MAPK1	7520
TAB2	7070
MAP2K4	6948
UBB	6737
NFKB1	6367
FBXW11	6282
MAP3K8	6262

Click HERE to show all gene set members

GeneID	Gene Rank
DUSP3	9324
MAPK14	9219
MAPK3	9078
MAP2K6	9010
MAP2K1	8960
MAP2K3	8785
NOD2	8393
PPP2CA	8308
MAPKAPK3	8255
MEF2A	8030
CHUK	7959
RPS6KA1	7800
PPP2CB	7769
MAPK1	7520
TAB2	7070
MAP2K4	6948
UBB	6737
NFKB1	6367
FBXW11	6282
MAP3K8	6262
FOS	6179
IRAK1	6159
ATF1	5790
TAB1	5711
UBE2V1	5681
TNIP2	5630
IKBKG	5434
PPP2R1A	4669
UBC	4421
DUSP6	4367
SKP1	4349
MAPKAPK2	4176
MAPK10	4136
JUN	3964
MAPK11	3955
RPS6KA2	3177
TAB3	3165
RPS6KA3	3012
MAP3K7	2453
PPP2R5D	2440
ATF2	2110
UBE2N	1951
MAP2K7	1647
VRK3	1293
UBA52	1071
RIPK2	1042
ELK1	1040
TRAF6	-241
PPP2R1B	-246
MEF2C	-319
MAPK7	-1294
CREB1	-1382
DUSP7	-3253
BTRC	-4932
IKBKB	-5290
DUSP4	-6432
RPS27A	-6894
MAPK9	-7182
MAPK8	-9646
IRAK2	-9718
CUL1	-11467
RPS6KA5	-11616
NOD1	-12234

---

Selenocysteine synthesis

	1060
set	Selenocysteine synthesis
setSize	92
pANOVA	6.15e-07
s.dist	-0.301
p.adjustANOVA	8.64e-06

Top enriched genes

GeneID	Gene Rank
SEPSECS	-11393
SECISBP2	-10495
EEFSEC	-10237
PSTK	-10177
RPS27	-9651
RPL23A	-9477
RPL39L	-8982
RPS20	-8922
RPL3	-8478
RPL35	-8239
RPL13A	-8123
RPS29	-7794
RPS18	-7641
RPL36A	-7442
RPS11	-7122
RPL12	-7038
RPS19	-7037
RPL30	-6995
RPLP2	-6915
RPS27A	-6894

Click HERE to show all gene set members

GeneID	Gene Rank
SEPSECS	-11393
SECISBP2	-10495
EEFSEC	-10237
PSTK	-10177
RPS27	-9651
RPL23A	-9477
RPL39L	-8982
RPS20	-8922
RPL3	-8478
RPL35	-8239
RPL13A	-8123
RPS29	-7794
RPS18	-7641
RPL36A	-7442
RPS11	-7122
RPL12	-7038
RPS19	-7037
RPL30	-6995
RPLP2	-6915
RPS27A	-6894
RPL41	-6877
RPL34	-6807
RPL10A	-6644
RPL26	-6636
RPL32	-6577
RPL10	-6562
RPL14	-6518
RPL21	-6481
RPL37	-6401
RPL27A	-6321
RPS23	-6279
RPL11	-6275
RPS25	-6246
RPL19	-6242
RPS17	-6223
RPSA	-6219
RPS6	-6100
RPL35A	-6080
RPL18A	-6029
RPS12	-5985
RPS4X	-5969
SARS1	-5960
RPL38	-5890
RPL24	-5882
RPS3	-5833
RPS15A	-5695
RPS10	-5686
RPS14	-5485
RPS5	-5478
RPL17	-5464
RPL36	-5287
RPL18	-5054
RPS7	-5016
RPL22	-4738
RPS3A	-4702
RPS28	-4647
RPL5	-4631
RPS16	-4570
RPS2	-4509
RPL31	-4507
RPS21	-4115
RPL37A	-4004
RPL7A	-3699
RPS15	-3698
RPL29	-3604
RPL4	-3592
RPL13	-3461
RPL6	-3382
RPL23	-3352
RPL39	-3047
RPL27	-2934
RPS8	-2138
RPL7	-2018
RPL9	-1827
RPS13	-1759
RPL22L1	-1643
RPL28	-1469
RPS26	-1443
RPL8	-1242
RPLP0	-1054
RPL15	-1017
FAU	-402
RPS24	-282
RPS4Y1	-222
RPLP1	-65
RPL36AL	91
UBA52	1071
RPS27L	2117
RPL3L	4539
RPS9	5496
RPL26L1	7295
SEPHS2	7779

---

Transcriptional regulation of granulopoiesis

	1264
set	Transcriptional regulation of granulopoiesis
setSize	46
pANOVA	6.81e-07
s.dist	0.423
p.adjustANOVA	9.48e-06

Top enriched genes

GeneID	Gene Rank
H2AJ	9418.0
H2BC21	9368.0
H2BC12	9178.0
SPI1	8907.0
CSF3R	8795.0
H3-3A	8754.0
TFDP1	8500.0
CEBPA	8386.0
IL6R	8229.0
H2BC5	8163.0
STAT3	8152.0
CEBPB	8108.0
H2BC11	8076.0
H2AC6	8070.0
RUNX1	7591.0
H2BC4	7549.0
RXRA	7513.0
H2BC17	7502.0
CEBPE	7447.0
H3C15	6780.5

Click HERE to show all gene set members

GeneID	Gene Rank
H2AJ	9418.0
H2BC21	9368.0
H2BC12	9178.0
SPI1	8907.0
CSF3R	8795.0
H3-3A	8754.0
TFDP1	8500.0
CEBPA	8386.0
IL6R	8229.0
H2BC5	8163.0
STAT3	8152.0
CEBPB	8108.0
H2BC11	8076.0
H2AC6	8070.0
RUNX1	7591.0
H2BC4	7549.0
RXRA	7513.0
H2BC17	7502.0
CEBPE	7447.0
H3C15	6780.5
TAL1	6644.0
E2F1	6473.0
RARA	6365.0
EP300	6208.0
H2AZ1	6126.0
FLI1	5589.0
H2BC9	5461.0
H2BC15	5458.0
KLF5	5053.0
H2AC20	5039.0
CDKN1A	4438.0
DEK	2655.0
MYC	2367.0
CBFB	2152.0
MYB	555.0
H2AZ2	-1266.0
CREB1	-1382.0
CDK2	-5018.0
H2BU1	-6519.0
LEF1	-7246.0
PML	-8888.0
GATA2	-9305.0
KMT2A	-10672.0
CDK4	-11138.0
GFI1	-11999.0
TFDP2	-12315.0

---

PIP3 activates AKT signaling

	791
set	PIP3 activates AKT signaling
setSize	241
pANOVA	7.21e-07
s.dist	0.185
p.adjustANOVA	9.79e-06

Top enriched genes

GeneID	Gene Rank
PPARG	9571
LAMTOR1	9450
GRB2	9320
PHC2	9103
AGO4	9094
RCOR1	9086
MAPK3	9078
VAPA	9073
PIK3CB	9065
TGFA	9031
KL	9019
MKRN1	8864
HGF	8856
RRAGD	8850
FOXO3	8729
RAC1	8720
SNAI1	8669
RNF146	8622
LAMTOR5	8611
RHOG	8544

Click HERE to show all gene set members

GeneID	Gene Rank
PPARG	9571
LAMTOR1	9450
GRB2	9320
PHC2	9103
AGO4	9094
RCOR1	9086
MAPK3	9078
VAPA	9073
PIK3CB	9065
TGFA	9031
KL	9019
MKRN1	8864
HGF	8856
RRAGD	8850
FOXO3	8729
RAC1	8720
SNAI1	8669
RNF146	8622
LAMTOR5	8611
RHOG	8544
PSMB7	8535
PTEN	8516
PSMD4	8498
PSME3	8331
IRS2	8323
PPP2CA	8308
EGF	8267
TRIM27	8257
PSMB5	8188
INSR	8103
MYD88	8091
WWP2	8046
VAV1	8021
CHUK	7959
AKT1S1	7902
PSMD6	7881
PIK3AP1	7836
GSK3A	7811
CASP9	7784
PPP2CB	7769
PSMD9	7712
LAMTOR2	7704
LAMTOR3	7692
RHEB	7675
IER3	7557
MAPK1	7520
PSMD2	7470
IL1RAP	7349
PSMA1	7346
PSMD1	7283
PSMB3	7265
PSMA7	7174
PSMC1	7096
BAD	7002
PSMB6	6927
PPP2R5B	6870
UBB	6737
PSMF1	6724
GSK3B	6720
PSMC6	6701
PSMD12	6537
PIP5K1B	6526
FOXO4	6493
CSNK2A2	6430
USP7	6410
RRAGA	6344
NEDD4	6330
PSMD11	6296
PDPK1	6209
CSNK2A1	6207
PIP5K1A	6198
IRAK1	6159
PIK3CD	6096
HDAC7	6070
PSMD7	6017
PDGFRA	6002
PSMD13	5991
PPP2R5A	5985
PSMA6	5978
PSMD8	5845
MAF1	5804
GAB1	5723
AGO1	5660
HDAC2	5569
CBX8	5523
AREG	5494
PDGFA	5484
PSMA2	5433
PTPN11	5383
RAC2	5238
MAPKAP1	5130
PIK3R2	5051
RRAGC	5033
HBEGF	4878
HDAC5	4761
HDAC3	4734
PIK3CA	4697
PSMD3	4693
PPP2R1A	4669
LAMTOR4	4487
CDKN1A	4438
SEM1	4436
UBC	4421
MDM2	4179
PSMB2	4103
CBX6	4091
NRG1	4018
CSNK2B	3987
JUN	3964
STRN	3758
FGF2	3660
PHLPP1	3657
AKT1	3656
RNF2	3573
PSMD5	3507
PIP5K1C	3436
PSMB1	3422
GATAD2A	3125
AGO2	3046
EGR1	2965
SLC38A9	2861
PSMD14	2703
PSMC2	2696
IL1RL1	2644
EPGN	2579
PSMB4	2552
MECOM	2503
PPP2R5D	2440
CBX4	2237
ATF2	2110
PSMC3	2018
EREG	1906
IRS1	1806
PSMD10	1646
XIAP	1478
UBA52	1071
REST	945
RPS6KB2	652
HDAC1	394
IL33	392
AKT2	345
ATN1	305
MLST8	304
FRK	94
CD86	-71
TRAF6	-241
PPP2R1B	-246
ERBB3	-468
TNKS2	-512
PSMA4	-538
MBD3	-546
PPP2R5E	-627
RRAGB	-689
TSC2	-804
PSMC5	-948
AGO3	-1014
STUB1	-1093
CREB1	-1382
GATAD2B	-1780
RBBP4	-1907
NRG4	-1939
PIP4K2A	-2339
SUZ12	-2444
FGFR4	-2892
MTA1	-2917
PSMB8	-3080
FRS2	-3430
CD19	-3769
FGF7	-3999
RING1	-4045
TNRC6B	-4558
CHD4	-4576
CBX2	-4693
PSMA3	-5314
FGFR1	-5335
PTENP1	-5342
SCMH1	-5553
TNRC6A	-5567
PSMB10	-5768
TRIB3	-5896
SALL4	-5965
PSME4	-6099
PSMA5	-6154
FOXO6	-6467
USP13	-6723
NR4A1	-6762
CD80	-6837
FGF23	-6840
RPS27A	-6894
TRAT1	-7043
MTA2	-7367
PSMA8	-7559
PIP4K2B	-7720
PHC1	-7816
PHC3	-8154
CDKN1B	-8305
PDGFB	-8575
FGF22	-8733
TNKS	-8839
ICOS	-8862
FGF9	-8873
PML	-8888
MTA3	-8918
SRC	-9011
FOXO1	-9173
ESR1	-9230
ESR2	-9236
PSMC4	-9306
EED	-9417
CHD3	-9466
KDM1A	-9476
RICTOR	-9593
PIK3R1	-9725
BMI1	-9787
CD28	-9858
EZH2	-9929
MTOR	-9948
PSME1	-10138
MIR25	-10321
PSME2	-10415
RPTOR	-10494
OTUD3	-10628
TP53	-10936
THEM4	-10987
KIT	-11031
PSMB9	-11362
PIP4K2C	-11384
CNOT6L	-11389
PPP2R5C	-11413
PDGFRB	-11452
LCK	-11492
TNRC6C	-11737
FGFR2	-11753
FYN	-11758
AKT3	-11804
PHLPP2	-11904
PRR5	-11948
MOV10	-11980
PIK3R3	-12037
RBBP7	-12085
ERBB2	-12281

---

Signaling by NOTCH4

	1116
set	Signaling by NOTCH4
setSize	79
pANOVA	7.25e-07
s.dist	0.322
p.adjustANOVA	9.79e-06

Top enriched genes

GeneID	Gene Rank
TACC3	9389
NCSTN	9139
MAML3	8965
RBPJ	8744
ADAM10	8705
JAG1	8661
PSMB7	8535
PSMD4	8498
PSME3	8331
PSMB5	8188
PSMD6	7881
PSEN1	7843
PSMD9	7712
PSMD2	7470
PSMA1	7346
PSMD1	7283
PSMB3	7265
PSMA7	7174
PSMC1	7096
PSMB6	6927

Click HERE to show all gene set members

GeneID	Gene Rank
TACC3	9389
NCSTN	9139
MAML3	8965
RBPJ	8744
ADAM10	8705
JAG1	8661
PSMB7	8535
PSMD4	8498
PSME3	8331
PSMB5	8188
PSMD6	7881
PSEN1	7843
PSMD9	7712
PSMD2	7470
PSMA1	7346
PSMD1	7283
PSMB3	7265
PSMA7	7174
PSMC1	7096
PSMB6	6927
UBB	6737
PSMF1	6724
PSMC6	6701
PSMD12	6537
PSMD11	6296
APH1B	6248
EP300	6208
PSMD7	6017
PSMD13	5991
PSMA6	5978
PSMD8	5845
PSENEN	5833
YWHAZ	5687
MAML1	5447
PSMA2	5433
NOTCH2	5276
SNW1	5255
NOTCH1	4733
PSMD3	4693
SEM1	4436
UBC	4421
SKP1	4349
APH1A	4198
PSMB2	4103
RBX1	4039
AKT1	3656
PSMD5	3507
CREBBP	3460
PSMB1	3422
PSMD14	2703
PSMC2	2696
PSMB4	2552
PSMC3	2018
PSMD10	1646
UBA52	1071
ACTA2	-430
MAML2	-476
PSMA4	-538
PSMC5	-948
KAT2B	-2393
PSMB8	-3080
MAMLD1	-4791
NOTCH4	-5200
PSMA3	-5314
PSMB10	-5768
PSMA5	-6154
FBXW7	-6709
RPS27A	-6894
FLT4	-7288
HES1	-7731
PSEN2	-7844
PSMC4	-9306
HEY2	-9918
PSME1	-10138
KAT2A	-10374
PSME2	-10415
PSMB9	-11362
CUL1	-11467
SMAD3	-11541

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.0.2 (2020-06-22)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 18.04.4 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.7.1
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.7.1
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.1.0               GGally_2.0.0               
##  [3] beeswarm_0.2.3              gtools_3.8.2               
##  [5] echarts4r_0.3.2             mitch_1.0.4                
##  [7] MASS_7.3-51.6               fgsea_1.14.0               
##  [9] gplots_3.0.3                DESeq2_1.28.1              
## [11] SummarizedExperiment_1.18.1 DelayedArray_0.14.0        
## [13] matrixStats_0.56.0          Biobase_2.48.0             
## [15] GenomicRanges_1.40.0        GenomeInfoDb_1.24.2        
## [17] IRanges_2.22.2              S4Vectors_0.26.1           
## [19] BiocGenerics_0.34.0         reshape2_1.4.4             
## [21] forcats_0.5.0               stringr_1.4.0              
## [23] dplyr_1.0.0                 purrr_0.3.4                
## [25] readr_1.3.1                 tidyr_1.1.0                
## [27] tibble_3.0.1                ggplot2_3.3.2              
## [29] tidyverse_1.3.0            
## 
## loaded via a namespace (and not attached):
##  [1] colorspace_1.4-1       ellipsis_0.3.1         rprojroot_1.3-2       
##  [4] XVector_0.28.0         fs_1.4.1               rstudioapi_0.11       
##  [7] farver_2.0.3           bit64_0.9-7            AnnotationDbi_1.50.0  
## [10] fansi_0.4.1            lubridate_1.7.9        xml2_1.3.2            
## [13] splines_4.0.2          geneplotter_1.66.0     knitr_1.28            
## [16] jsonlite_1.6.1         broom_0.5.6            annotate_1.66.0       
## [19] dbplyr_1.4.4           shiny_1.4.0.2          compiler_4.0.2        
## [22] httr_1.4.1             backports_1.1.8        fastmap_1.0.1         
## [25] assertthat_0.2.1       Matrix_1.2-18          cli_2.0.2             
## [28] later_1.1.0.1          htmltools_0.5.0        tools_4.0.2           
## [31] gtable_0.3.0           glue_1.4.1             GenomeInfoDbData_1.2.3
## [34] fastmatch_1.1-0        Rcpp_1.0.4.6           cellranger_1.1.0      
## [37] vctrs_0.3.1            gdata_2.18.0           nlme_3.1-148          
## [40] xfun_0.15              testthat_2.3.2         rvest_0.3.5           
## [43] mime_0.9               lifecycle_0.2.0        XML_3.99-0.3          
## [46] zlibbioc_1.34.0        scales_1.1.1           promises_1.1.1        
## [49] hms_0.5.3              RColorBrewer_1.1-2     yaml_2.2.1            
## [52] memoise_1.1.0          gridExtra_2.3          reshape_0.8.8         
## [55] stringi_1.4.6          RSQLite_2.2.0          highr_0.8             
## [58] genefilter_1.70.0      desc_1.2.0             caTools_1.18.0        
## [61] BiocParallel_1.22.0    rlang_0.4.6            pkgconfig_2.0.3       
## [64] bitops_1.0-6           evaluate_0.14          lattice_0.20-41       
## [67] labeling_0.3           htmlwidgets_1.5.1      bit_1.1-15.2          
## [70] tidyselect_1.1.0       plyr_1.8.6             magrittr_1.5          
## [73] R6_2.4.1               generics_0.0.2         DBI_1.1.0             
## [76] pillar_1.4.4           haven_2.3.1            withr_2.2.0           
## [79] survival_3.2-3         RCurl_1.98-1.2         modelr_0.1.8          
## [82] crayon_1.3.4           KernSmooth_2.23-17     rmarkdown_2.3         
## [85] locfit_1.5-9.4         grid_4.0.2             readxl_1.3.1          
## [88] data.table_1.12.8      blob_1.2.1             reprex_0.3.0          
## [91] digest_0.6.25          pbmcapply_1.5.0        xtable_1.8-4          
## [94] httpuv_1.5.4           munsell_0.5.0

END of report