date generated: 2022-01-20

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

##                 x
## A1BG    4.1644895
## A1CF    2.8783151
## A2M     0.3828562
## A4GALT  1.0571952
## AAAS    1.0071471
## AACS   -2.0539621
Here are some metrics about the input data profile:
Profile metrics
Profile metrics
num_genesets 2512
num_genes_in_profile 14533
duplicated_genes_present 0
num_profile_genes_in_sets 7596
num_profile_genes_not_in_sets 6937

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt
Gene sets metrics
Gene sets metrics
num_genesets 2512
num_genesets_excluded 1135
num_genesets_included 1377

Differential pathway expression


Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets
set setSize pANOVA s.dist p.adjustANOVA
Cellular responses to stimuli 641 1.36e-21 -0.222 1.87e-18
Cellular responses to stress 633 2.20e-20 -0.217 1.51e-17
Infectious disease 637 1.06e-18 -0.206 4.88e-16
SRP-dependent cotranslational protein targeting to membrane 109 1.48e-17 -0.473 5.09e-15
Asparagine N-linked glycosylation 252 6.70e-17 -0.306 1.85e-14
Axon guidance 424 2.94e-16 -0.232 6.75e-14
Cellular response to starvation 149 2.02e-14 -0.363 3.98e-12
Metabolism of proteins 1550 3.25e-14 -0.118 5.59e-12
Nervous system development 444 6.25e-14 -0.209 9.56e-12
L13a-mediated translational silencing of Ceruloplasmin expression 108 4.15e-13 -0.404 5.71e-11
GTP hydrolysis and joining of the 60S ribosomal subunit 109 5.93e-13 -0.399 6.44e-11
Developmental Biology 677 6.00e-13 -0.163 6.44e-11
Signal Transduction 1748 6.08e-13 -0.106 6.44e-11
Cholesterol biosynthesis 24 8.63e-13 0.843 8.49e-11
Translation 270 9.51e-13 -0.253 8.73e-11
Cap-dependent Translation Initiation 116 1.61e-12 -0.380 1.30e-10
Eukaryotic Translation Initiation 116 1.61e-12 -0.380 1.30e-10
Regulation of expression of SLITs and ROBOs 157 2.15e-12 -0.325 1.65e-10
Signaling by ROBO receptors 193 2.58e-12 -0.293 1.87e-10
Diseases of signal transduction by growth factor receptors and second messengers 361 3.78e-12 -0.214 2.60e-10
Response of EIF2AK4 (GCN2) to amino acid deficiency 98 7.59e-12 -0.400 4.98e-10
Formation of a pool of free 40S subunits 98 1.12e-11 -0.397 6.94e-10
Metabolism of RNA 658 1.16e-11 -0.156 6.94e-10
Eukaryotic Translation Elongation 91 2.06e-11 -0.407 1.18e-09
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 91 2.32e-11 -0.406 1.27e-09
Disease 1247 2.40e-11 -0.114 1.27e-09
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 111 3.73e-11 -0.364 1.83e-09
Nonsense-Mediated Decay (NMD) 111 3.73e-11 -0.364 1.83e-09
Viral mRNA Translation 86 5.18e-11 -0.410 2.46e-09
Influenza Infection 151 6.29e-11 -0.309 2.89e-09
rRNA processing in the nucleus and cytosol 184 7.82e-11 -0.278 3.47e-09
Peptide chain elongation 86 8.24e-11 -0.405 3.55e-09
Immune System 1374 8.91e-11 -0.106 3.72e-09
SARS-CoV Infections 144 1.05e-10 -0.312 4.26e-09
Unfolded Protein Response (UPR) 89 1.43e-10 -0.393 5.62e-09
Major pathway of rRNA processing in the nucleolus and cytosol 174 1.91e-10 -0.280 7.29e-09
Eukaryotic Translation Termination 89 2.80e-10 -0.387 1.04e-08
Vesicle-mediated transport 555 7.17e-10 -0.154 2.60e-08
Signaling by Receptor Tyrosine Kinases 405 7.81e-10 -0.179 2.76e-08
Membrane Trafficking 531 9.78e-10 -0.156 3.37e-08
Selenocysteine synthesis 89 1.00e-09 -0.375 3.37e-08
IRE1alpha activates chaperones 50 2.24e-09 -0.489 7.35e-08
Transport to the Golgi and subsequent modification 146 2.45e-09 -0.286 7.84e-08
DNA strand elongation 32 3.66e-09 0.602 1.15e-07
PIP3 activates AKT signaling 223 6.57e-09 -0.226 2.01e-07
N-glycan trimming in the ER and Calnexin/Calreticulin cycle 34 7.03e-09 -0.574 2.11e-07
Innate Immune System 740 9.58e-09 -0.125 2.81e-07
Ribosomal scanning and start codon recognition 58 1.02e-08 -0.435 2.93e-07
ER to Golgi Anterograde Transport 122 1.24e-08 -0.299 3.49e-07
Selenoamino acid metabolism 104 1.30e-08 -0.323 3.57e-07


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pANOVA s.dist p.adjustANOVA
Cellular responses to stimuli 641 1.36e-21 -0.222000 1.87e-18
Cellular responses to stress 633 2.20e-20 -0.217000 1.51e-17
Infectious disease 637 1.06e-18 -0.206000 4.88e-16
SRP-dependent cotranslational protein targeting to membrane 109 1.48e-17 -0.473000 5.09e-15
Asparagine N-linked glycosylation 252 6.70e-17 -0.306000 1.85e-14
Axon guidance 424 2.94e-16 -0.232000 6.75e-14
Cellular response to starvation 149 2.02e-14 -0.363000 3.98e-12
Metabolism of proteins 1550 3.25e-14 -0.118000 5.59e-12
Nervous system development 444 6.25e-14 -0.209000 9.56e-12
L13a-mediated translational silencing of Ceruloplasmin expression 108 4.15e-13 -0.404000 5.71e-11
GTP hydrolysis and joining of the 60S ribosomal subunit 109 5.93e-13 -0.399000 6.44e-11
Developmental Biology 677 6.00e-13 -0.163000 6.44e-11
Signal Transduction 1748 6.08e-13 -0.106000 6.44e-11
Cholesterol biosynthesis 24 8.63e-13 0.843000 8.49e-11
Translation 270 9.51e-13 -0.253000 8.73e-11
Cap-dependent Translation Initiation 116 1.61e-12 -0.380000 1.30e-10
Eukaryotic Translation Initiation 116 1.61e-12 -0.380000 1.30e-10
Regulation of expression of SLITs and ROBOs 157 2.15e-12 -0.325000 1.65e-10
Signaling by ROBO receptors 193 2.58e-12 -0.293000 1.87e-10
Diseases of signal transduction by growth factor receptors and second messengers 361 3.78e-12 -0.214000 2.60e-10
Response of EIF2AK4 (GCN2) to amino acid deficiency 98 7.59e-12 -0.400000 4.98e-10
Formation of a pool of free 40S subunits 98 1.12e-11 -0.397000 6.94e-10
Metabolism of RNA 658 1.16e-11 -0.156000 6.94e-10
Eukaryotic Translation Elongation 91 2.06e-11 -0.407000 1.18e-09
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 91 2.32e-11 -0.406000 1.27e-09
Disease 1247 2.40e-11 -0.114000 1.27e-09
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 111 3.73e-11 -0.364000 1.83e-09
Nonsense-Mediated Decay (NMD) 111 3.73e-11 -0.364000 1.83e-09
Viral mRNA Translation 86 5.18e-11 -0.410000 2.46e-09
Influenza Infection 151 6.29e-11 -0.309000 2.89e-09
rRNA processing in the nucleus and cytosol 184 7.82e-11 -0.278000 3.47e-09
Peptide chain elongation 86 8.24e-11 -0.405000 3.55e-09
Immune System 1374 8.91e-11 -0.106000 3.72e-09
SARS-CoV Infections 144 1.05e-10 -0.312000 4.26e-09
Unfolded Protein Response (UPR) 89 1.43e-10 -0.393000 5.62e-09
Major pathway of rRNA processing in the nucleolus and cytosol 174 1.91e-10 -0.280000 7.29e-09
Eukaryotic Translation Termination 89 2.80e-10 -0.387000 1.04e-08
Vesicle-mediated transport 555 7.17e-10 -0.154000 2.60e-08
Signaling by Receptor Tyrosine Kinases 405 7.81e-10 -0.179000 2.76e-08
Membrane Trafficking 531 9.78e-10 -0.156000 3.37e-08
Selenocysteine synthesis 89 1.00e-09 -0.375000 3.37e-08
IRE1alpha activates chaperones 50 2.24e-09 -0.489000 7.35e-08
Transport to the Golgi and subsequent modification 146 2.45e-09 -0.286000 7.84e-08
DNA strand elongation 32 3.66e-09 0.602000 1.15e-07
PIP3 activates AKT signaling 223 6.57e-09 -0.226000 2.01e-07
N-glycan trimming in the ER and Calnexin/Calreticulin cycle 34 7.03e-09 -0.574000 2.11e-07
Innate Immune System 740 9.58e-09 -0.125000 2.81e-07
Ribosomal scanning and start codon recognition 58 1.02e-08 -0.435000 2.93e-07
ER to Golgi Anterograde Transport 122 1.24e-08 -0.299000 3.49e-07
Selenoamino acid metabolism 104 1.30e-08 -0.323000 3.57e-07
Translation initiation complex formation 58 1.63e-08 -0.429000 4.39e-07
XBP1(S) activates chaperone genes 48 2.02e-08 -0.468000 5.36e-07
Diseases of DNA repair 34 3.47e-08 0.547000 9.02e-07
Influenza Viral RNA Transcription and Replication 132 4.62e-08 -0.276000 1.18e-06
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 59 4.97e-08 -0.410000 1.24e-06
Calnexin/calreticulin cycle 25 5.76e-08 -0.627000 1.41e-06
Post-translational protein modification 1138 5.82e-08 -0.096700 1.41e-06
rRNA processing 205 7.31e-08 -0.219000 1.74e-06
Intracellular signaling by second messengers 252 7.50e-08 -0.197000 1.75e-06
Homologous DNA Pairing and Strand Exchange 42 8.69e-08 0.477000 1.99e-06
Formation of the ternary complex, and subsequently, the 43S complex 51 8.98e-08 -0.433000 2.03e-06
Signaling by Interleukins 315 9.78e-08 -0.175000 2.17e-06
Signaling by NTRK1 (TRKA) 102 1.00e-07 -0.305000 2.19e-06
Mitotic Prometaphase 181 1.19e-07 0.229000 2.56e-06
Resolution of D-loop Structures through Holliday Junction Intermediates 32 1.27e-07 0.540000 2.69e-06
Biological oxidations 155 1.42e-07 0.245000 2.95e-06
Regulation of Complement cascade 30 1.43e-07 0.555000 2.95e-06
SARS-CoV-2 Infection 69 2.16e-07 -0.361000 4.38e-06
Autophagy 121 2.79e-07 -0.271000 5.57e-06
Signaling by the B Cell Receptor (BCR) 96 2.97e-07 -0.303000 5.83e-06
Complement cascade 35 3.48e-07 0.498000 6.75e-06
Cell Cycle 594 3.79e-07 0.123000 7.25e-06
MAPK family signaling cascades 244 3.99e-07 -0.189000 7.52e-06
Transport of small molecules 535 4.55e-07 -0.128000 8.48e-06
TCR signaling 91 4.87e-07 -0.305000 8.93e-06
Resolution of D-Loop Structures 33 4.98e-07 0.506000 9.02e-06
Homology Directed Repair 101 5.14e-07 0.289000 9.20e-06
RHO GTPase cycle 387 8.32e-07 -0.147000 1.47e-05
Fc epsilon receptor (FCERI) signaling 113 8.53e-07 -0.268000 1.49e-05
Defective HDR through Homologous Recombination (HRR) due to BRCA1 loss-of-function 24 1.16e-06 0.573000 1.89e-05
Defective HDR through Homologous Recombination (HRR) due to PALB2 loss of function 24 1.16e-06 0.573000 1.89e-05
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function 24 1.16e-06 0.573000 1.89e-05
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function 24 1.16e-06 0.573000 1.89e-05
Diseases of DNA Double-Strand Break Repair 24 1.16e-06 0.573000 1.89e-05
Presynaptic phase of homologous DNA pairing and strand exchange 39 1.19e-06 0.449000 1.92e-05
Macroautophagy 108 1.20e-06 -0.271000 1.92e-05
HDR through Homologous Recombination (HRR) 66 1.28e-06 0.345000 2.02e-05
RAF/MAP kinase cascade 207 1.35e-06 -0.195000 2.11e-05
Chromosome Maintenance 90 1.39e-06 0.295000 2.12e-05
MyD88 cascade initiated on plasma membrane 77 1.41e-06 -0.318000 2.12e-05
Toll Like Receptor 10 (TLR10) Cascade 77 1.41e-06 -0.318000 2.12e-05
Toll Like Receptor 5 (TLR5) Cascade 77 1.41e-06 -0.318000 2.12e-05
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 26 1.60e-06 0.544000 2.37e-05
Downstream signaling events of B Cell Receptor (BCR) 74 1.63e-06 -0.323000 2.39e-05
COPI-mediated anterograde transport 74 1.83e-06 -0.321000 2.65e-05
Signaling by WNT 213 1.90e-06 -0.190000 2.71e-05
Toll Like Receptor 3 (TLR3) Cascade 85 1.91e-06 -0.299000 2.71e-05
Cytokine Signaling in Immune system 492 2.02e-06 -0.126000 2.84e-05
ER Quality Control Compartment (ERQC) 20 2.26e-06 -0.611000 3.12e-05
Hh mutants are degraded by ERAD 53 2.27e-06 -0.376000 3.12e-05
Signaling by NTRKs 115 2.52e-06 -0.254000 3.44e-05
MyD88 dependent cascade initiated on endosome 81 2.86e-06 -0.301000 3.79e-05
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 81 2.86e-06 -0.301000 3.79e-05
Toll Like Receptor 7/8 (TLR7/8) Cascade 81 2.86e-06 -0.301000 3.79e-05
Hh mutants abrogate ligand secretion 55 3.23e-06 -0.363000 4.24e-05
Hedgehog ligand biogenesis 59 3.35e-06 -0.350000 4.35e-05
MAPK1/MAPK3 signaling 212 3.38e-06 -0.186000 4.35e-05
Signaling by Insulin receptor 59 3.60e-06 -0.349000 4.60e-05
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 95 3.73e-06 0.275000 4.67e-05
Toll Like Receptor 9 (TLR9) Cascade 85 3.75e-06 -0.290000 4.67e-05
Defective CFTR causes cystic fibrosis 56 3.77e-06 -0.357000 4.67e-05
Unwinding of DNA 12 4.06e-06 0.768000 4.99e-05
MyD88-independent TLR4 cascade 88 4.92e-06 -0.282000 5.94e-05
TRIF(TICAM1)-mediated TLR4 signaling 88 4.92e-06 -0.282000 5.94e-05
Downstream TCR signaling 76 4.96e-06 -0.303000 5.94e-05
Fatty acid metabolism 130 6.13e-06 0.230000 7.27e-05
Activation of ATR in response to replication stress 37 7.05e-06 0.427000 8.29e-05
Phase II - Conjugation of compounds 75 7.40e-06 0.299000 8.64e-05
Chromatin modifying enzymes 195 8.16e-06 -0.186000 9.37e-05
Chromatin organization 195 8.16e-06 -0.186000 9.37e-05
Degradation of beta-catenin by the destruction complex 80 8.54e-06 -0.288000 9.72e-05
DNA Double-Strand Break Repair 127 9.98e-06 0.227000 1.13e-04
Cell Cycle, Mitotic 478 1.02e-05 0.118000 1.15e-04
MAP kinase activation 61 1.03e-05 -0.327000 1.15e-04
Activation of NF-kappaB in B cells 62 1.07e-05 -0.323000 1.18e-04
PTEN Regulation 134 1.09e-05 -0.220000 1.19e-04
Regulation of HMOX1 expression and activity 62 1.18e-05 -0.322000 1.28e-04
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane 19 1.22e-05 -0.580000 1.31e-04
Adaptive Immune System 551 1.25e-05 -0.110000 1.34e-04
Insulin receptor recycling 23 1.37e-05 -0.524000 1.45e-04
Interleukin-17 signaling 65 1.41e-05 -0.312000 1.49e-04
Cilium Assembly 172 1.43e-05 0.192000 1.49e-04
Deposition of new CENPA-containing nucleosomes at the centromere 27 1.69e-05 0.478000 1.74e-04
Nucleosome assembly 27 1.69e-05 0.478000 1.74e-04
RAC3 GTPase cycle 79 1.72e-05 -0.280000 1.76e-04
trans-Golgi Network Vesicle Budding 68 1.85e-05 -0.300000 1.88e-04
Interleukin-1 signaling 92 2.33e-05 -0.255000 2.34e-04
Deubiquitination 218 2.36e-05 -0.167000 2.35e-04
DNA Repair 276 2.51e-05 0.148000 2.49e-04
HDR through Single Strand Annealing (SSA) 37 2.53e-05 0.400000 2.49e-04
UCH proteinases 81 2.63e-05 -0.270000 2.57e-04
COPII-mediated vesicle transport 63 2.73e-05 -0.306000 2.65e-04
Cytoprotection by HMOX1 118 2.94e-05 -0.223000 2.83e-04
Regulation of RUNX2 expression and activity 62 3.63e-05 -0.303000 3.48e-04
RAC2 GTPase cycle 75 3.85e-05 -0.275000 3.66e-04
Signaling by NOTCH 156 3.98e-05 -0.191000 3.75e-04
ROS sensing by NFE2L2 54 4.25e-05 -0.322000 3.98e-04
Telomere C-strand (Lagging Strand) Synthesis 34 4.74e-05 0.403000 4.41e-04
FCERI mediated NF-kB activation 70 5.17e-05 -0.280000 4.78e-04
Degradation of AXIN 52 5.39e-05 -0.324000 4.95e-04
Circadian Clock 65 5.64e-05 -0.289000 5.14e-04
Potential therapeutics for SARS 77 5.98e-05 -0.265000 5.42e-04
ABC transporter disorders 70 6.06e-05 -0.277000 5.45e-04
ABC-family proteins mediated transport 92 6.17e-05 -0.242000 5.51e-04
Cell Cycle Checkpoints 249 6.20e-05 0.148000 5.51e-04
Regulation of PTEN stability and activity 64 6.54e-05 -0.289000 5.77e-04
C-type lectin receptors (CLRs) 113 6.70e-05 -0.217000 5.88e-04
Nuclear Events (kinase and transcription factor activation) 56 7.25e-05 -0.307000 6.32e-04
TCF dependent signaling in response to WNT 145 7.77e-05 -0.190000 6.73e-04
Negative regulation of MAPK pathway 41 7.97e-05 -0.356000 6.86e-04
Regulation of mRNA stability by proteins that bind AU-rich elements 86 8.18e-05 -0.246000 6.93e-04
Transferrin endocytosis and recycling 29 8.19e-05 -0.423000 6.93e-04
MyD88 deficiency (TLR2/4) 11 8.20e-05 0.686000 6.93e-04
Cellular response to chemical stress 145 9.16e-05 -0.188000 7.69e-04
Interleukin-1 family signaling 111 9.25e-05 -0.215000 7.72e-04
mRNA Splicing - Major Pathway 178 9.49e-05 -0.170000 7.86e-04
Cargo concentration in the ER 27 9.54e-05 -0.434000 7.86e-04
Lagging Strand Synthesis 20 1.02e-04 0.502000 8.37e-04
CLEC7A (Dectin-1) signaling 92 1.03e-04 -0.234000 8.37e-04
Mitotic Spindle Checkpoint 107 1.03e-04 0.217000 8.37e-04
IRAK4 deficiency (TLR2/4) 12 1.08e-04 0.646000 8.69e-04
Signaling by VEGF 89 1.11e-04 -0.237000 8.85e-04
Dectin-1 mediated noncanonical NF-kB signaling 58 1.19e-04 -0.292000 9.46e-04
NIK–>noncanonical NF-kB signaling 56 1.21e-04 -0.297000 9.59e-04
Regulation of RUNX3 expression and activity 54 1.22e-04 -0.302000 9.59e-04
Activation of the pre-replicative complex 32 1.24e-04 0.392000 9.73e-04
TGF-beta receptor signaling activates SMADs 31 1.27e-04 -0.398000 9.85e-04
RAC1 GTPase cycle 149 1.36e-04 -0.181000 1.05e-03
mRNA Splicing 186 1.41e-04 -0.162000 1.09e-03
Activation of gene expression by SREBF (SREBP) 42 1.71e-04 0.335000 1.31e-03
Base Excision Repair 45 1.74e-04 0.324000 1.32e-03
MAPK6/MAPK4 signaling 79 1.78e-04 -0.244000 1.35e-03
Ubiquitin-dependent degradation of Cyclin D 49 1.88e-04 -0.308000 1.42e-03
RHOG GTPase cycle 66 1.96e-04 -0.265000 1.47e-03
Degradation of GLI1 by the proteasome 55 2.04e-04 -0.290000 1.52e-03
AUF1 (hnRNP D0) binds and destabilizes mRNA 52 2.07e-04 -0.298000 1.53e-03
Processive synthesis on the lagging strand 15 2.13e-04 0.552000 1.57e-03
Anchoring of the basal body to the plasma membrane 93 2.23e-04 0.222000 1.63e-03
Degradation of GLI2 by the proteasome 55 2.28e-04 -0.287000 1.65e-03
GLI3 is processed to GLI3R by the proteasome 55 2.28e-04 -0.287000 1.65e-03
Iron uptake and transport 55 2.28e-04 -0.287000 1.65e-03
Transcriptional regulation by RUNX3 91 2.37e-04 -0.223000 1.70e-03
Transport of inorganic cations/anions and amino acids/oligopeptides 71 2.40e-04 -0.252000 1.71e-03
Lysosome Vesicle Biogenesis 31 2.40e-04 -0.381000 1.71e-03
AURKA Activation by TPX2 69 2.42e-04 0.256000 1.71e-03
Neutrophil degranulation 352 2.53e-04 -0.114000 1.77e-03
Degradation of DVL 53 2.57e-04 -0.290000 1.80e-03
Initial triggering of complement 12 2.72e-04 0.607000 1.89e-03
Glutathione conjugation 29 2.74e-04 0.390000 1.90e-03
Extension of Telomeres 50 2.83e-04 0.297000 1.95e-03
Heme signaling 42 2.87e-04 -0.323000 1.97e-03
Intra-Golgi and retrograde Golgi-to-ER traffic 170 2.96e-04 -0.161000 2.00e-03
PCP/CE pathway 79 2.96e-04 -0.236000 2.00e-03
Regulation of activated PAK-2p34 by proteasome mediated degradation 47 2.97e-04 -0.305000 2.00e-03
Resolution of Sister Chromatid Cohesion 103 3.00e-04 0.206000 2.02e-03
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 51 3.02e-04 -0.293000 2.02e-03
Regulation of TLR by endogenous ligand 12 3.09e-04 0.601000 2.06e-03
Signaling by TGF-beta Receptor Complex 73 3.19e-04 -0.244000 2.11e-03
Golgi Associated Vesicle Biogenesis 55 3.31e-04 -0.280000 2.18e-03
Ub-specific processing proteases 150 3.35e-04 -0.170000 2.19e-03
Amino acids regulate mTORC1 51 3.84e-04 -0.288000 2.51e-03
Processing of Capped Intron-Containing Pre-mRNA 236 3.92e-04 -0.134000 2.55e-03
PI3K/AKT Signaling in Cancer 68 4.22e-04 -0.247000 2.71e-03
Leading Strand Synthesis 14 4.25e-04 0.544000 2.71e-03
Polymerase switching 14 4.25e-04 0.544000 2.71e-03
EML4 and NUDC in mitotic spindle formation 94 4.25e-04 0.210000 2.71e-03
ROS and RNS production in phagocytes 27 4.38e-04 -0.391000 2.78e-03
Collagen chain trimerization 18 4.42e-04 0.478000 2.79e-03
Signalling to ERKs 31 4.50e-04 -0.364000 2.83e-03
Formation of Fibrin Clot (Clotting Cascade) 28 4.53e-04 0.383000 2.83e-03
Toll-like Receptor Cascades 126 4.59e-04 -0.181000 2.86e-03
Signaling by EGFR 44 4.63e-04 -0.305000 2.87e-03
Transcriptional regulation by RUNX2 96 4.96e-04 -0.206000 3.06e-03
Cellular response to hypoxia 72 5.07e-04 -0.237000 3.12e-03
Autodegradation of the E3 ubiquitin ligase COP1 49 5.22e-04 -0.287000 3.18e-03
Negative regulation of NOTCH4 signaling 52 5.25e-04 -0.278000 3.18e-03
Amino acid transport across the plasma membrane 28 5.25e-04 -0.379000 3.18e-03
VEGFA-VEGFR2 Pathway 83 5.69e-04 -0.219000 3.43e-03
Removal of the Flap Intermediate 14 5.71e-04 0.532000 3.43e-03
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 63 5.75e-04 -0.251000 3.44e-03
Transcriptional regulation by RUNX1 147 5.80e-04 -0.165000 3.46e-03
Recruitment of NuMA to mitotic centrosomes 77 5.95e-04 0.227000 3.53e-03
Uptake and actions of bacterial toxins 22 6.22e-04 -0.421000 3.68e-03
Polymerase switching on the C-strand of the telomere 26 6.31e-04 0.387000 3.71e-03
RUNX1 regulates transcription of genes involved in differentiation of HSCs 61 6.38e-04 -0.253000 3.74e-03
Regulation of RAS by GAPs 62 6.62e-04 -0.250000 3.83e-03
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 90 6.63e-04 0.208000 3.83e-03
Amplification of signal from the kinetochores 90 6.63e-04 0.208000 3.83e-03
Resolution of Abasic Sites (AP sites) 37 6.97e-04 0.322000 3.98e-03
Loss of Nlp from mitotic centrosomes 66 6.97e-04 0.241000 3.98e-03
Loss of proteins required for interphase microtubule organization from the centrosome 66 6.97e-04 0.241000 3.98e-03
Signaling by NOTCH4 75 7.22e-04 -0.226000 4.11e-03
Regulation of TP53 Activity through Acetylation 29 7.88e-04 -0.360000 4.45e-03
PI Metabolism 71 7.89e-04 -0.231000 4.45e-03
Downregulation of TGF-beta receptor signaling 25 8.23e-04 -0.387000 4.62e-03
Vif-mediated degradation of APOBEC3G 51 8.63e-04 -0.270000 4.83e-03
Regulation of ornithine decarboxylase (ODC) 48 8.92e-04 -0.277000 4.97e-03
SCF-beta-TrCP mediated degradation of Emi1 52 9.06e-04 -0.266000 5.03e-03
Clathrin-mediated endocytosis 116 9.37e-04 -0.178000 5.18e-03
Class I MHC mediated antigen processing & presentation 331 9.63e-04 -0.106000 5.31e-03
Meiotic recombination 22 9.76e-04 0.406000 5.34e-03
Hedgehog ‘on’ state 75 9.78e-04 -0.220000 5.34e-03
Centrosome maturation 78 9.92e-04 0.216000 5.38e-03
Recruitment of mitotic centrosome proteins and complexes 78 9.92e-04 0.216000 5.38e-03
Fanconi Anemia Pathway 36 1.01e-03 0.317000 5.47e-03
AKT phosphorylates targets in the cytosol 13 1.07e-03 -0.524000 5.75e-03
Regulation of Apoptosis 50 1.09e-03 -0.267000 5.82e-03
Beta-catenin independent WNT signaling 117 1.09e-03 -0.175000 5.82e-03
HDMs demethylate histones 21 1.12e-03 -0.411000 5.93e-03
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 566 1.13e-03 -0.080600 5.98e-03
Host Interactions of HIV factors 122 1.17e-03 -0.170000 6.16e-03
MyD88:MAL(TIRAP) cascade initiated on plasma membrane 88 1.19e-03 -0.200000 6.17e-03
Toll Like Receptor 2 (TLR2) Cascade 88 1.19e-03 -0.200000 6.17e-03
Toll Like Receptor TLR1:TLR2 Cascade 88 1.19e-03 -0.200000 6.17e-03
Toll Like Receptor TLR6:TLR2 Cascade 88 1.19e-03 -0.200000 6.17e-03
Telomere Maintenance 65 1.35e-03 0.230000 6.98e-03
Cross-presentation of soluble exogenous antigens (endosomes) 42 1.35e-03 -0.286000 6.98e-03
G2/M DNA damage checkpoint 60 1.41e-03 0.239000 7.22e-03
RHOV GTPase cycle 35 1.47e-03 -0.311000 7.53e-03
Regulation of actin dynamics for phagocytic cup formation 49 1.53e-03 -0.262000 7.79e-03
MAP3K8 (TPL2)-dependent MAPK1/3 activation 16 1.55e-03 -0.457000 7.88e-03
Vpu mediated degradation of CD4 49 1.65e-03 -0.260000 8.36e-03
Negative regulation of the PI3K/AKT network 74 1.68e-03 -0.211000 8.48e-03
MAPK targets/ Nuclear events mediated by MAP kinases 30 1.69e-03 -0.331000 8.49e-03
Infection with Mycobacterium tuberculosis 22 1.71e-03 -0.386000 8.54e-03
TBC/RABGAPs 43 1.74e-03 -0.276000 8.70e-03
HIV Infection 217 1.79e-03 -0.123000 8.87e-03
Toll Like Receptor 4 (TLR4) Cascade 110 1.80e-03 -0.172000 8.92e-03
Fcgamma receptor (FCGR) dependent phagocytosis 70 1.82e-03 -0.216000 8.99e-03
EPH-Ephrin signaling 80 1.87e-03 -0.201000 9.21e-03
Signaling by EGFR in Cancer 22 1.96e-03 -0.381000 9.60e-03
Nuclear Receptor transcription pathway 41 1.97e-03 -0.279000 9.60e-03
Intraflagellar transport 34 2.00e-03 0.306000 9.71e-03
Signaling by NOTCH1 62 2.00e-03 -0.227000 9.71e-03
RHOQ GTPase cycle 54 2.03e-03 -0.243000 9.83e-03
Response of Mtb to phagocytosis 21 2.12e-03 -0.387000 1.02e-02
Base-Excision Repair, AP Site Formation 18 2.12e-03 0.418000 1.02e-02
Retrograde transport at the Trans-Golgi-Network 48 2.25e-03 -0.255000 1.08e-02
RHOBTB GTPase Cycle 33 2.26e-03 -0.307000 1.08e-02
TNFR2 non-canonical NF-kB pathway 77 2.26e-03 -0.201000 1.08e-02
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 14 2.34e-03 0.470000 1.11e-02
rRNA modification in the nucleus and cytosol 58 2.47e-03 -0.230000 1.17e-02
ESR-mediated signaling 138 2.49e-03 -0.149000 1.17e-02
The role of GTSE1 in G2/M progression after G2 checkpoint 57 2.56e-03 -0.231000 1.20e-02
SARS-CoV-1 Infection 48 2.57e-03 -0.252000 1.20e-02
Disorders of transmembrane transporters 140 2.57e-03 -0.148000 1.20e-02
Folding of actin by CCT/TriC 10 2.64e-03 -0.549000 1.22e-02
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 14 2.72e-03 0.463000 1.26e-02
Stabilization of p53 54 2.74e-03 -0.236000 1.26e-02
Cell-extracellular matrix interactions 14 2.88e-03 -0.460000 1.32e-02
Uptake and function of anthrax toxins 11 2.92e-03 -0.518000 1.33e-02
NGF-stimulated transcription 35 2.92e-03 -0.291000 1.33e-02
Response of EIF2AK1 (HRI) to heme deficiency 15 2.96e-03 -0.443000 1.35e-02
Metabolism of polyamines 56 3.00e-03 -0.229000 1.36e-02
Signaling by FGFR4 31 3.05e-03 -0.307000 1.38e-02
EGFR downregulation 26 3.06e-03 -0.336000 1.38e-02
Ion channel transport 116 3.09e-03 -0.159000 1.39e-02
Extra-nuclear estrogen signaling 57 3.21e-03 -0.226000 1.43e-02
Signaling by Rho GTPases 551 3.22e-03 -0.073900 1.43e-02
Peroxisomal protein import 57 3.37e-03 0.225000 1.50e-02
Cleavage of the damaged pyrimidine 16 3.50e-03 0.422000 1.54e-02
Depyrimidination 16 3.50e-03 0.422000 1.54e-02
Recognition and association of DNA glycosylase with site containing an affected pyrimidine 16 3.50e-03 0.422000 1.54e-02
Mismatch Repair 15 3.54e-03 0.435000 1.55e-02
Cargo recognition for clathrin-mediated endocytosis 81 3.58e-03 -0.187000 1.56e-02
TP53 Regulates Metabolic Genes 84 3.78e-03 -0.183000 1.64e-02
Signaling by TGFB family members 87 3.78e-03 -0.180000 1.64e-02
Apoptosis 153 3.86e-03 -0.136000 1.67e-02
Antigen Presentation: Folding, assembly and peptide loading of class I MHC 22 3.93e-03 -0.355000 1.70e-02
Interleukin-12 signaling 38 4.14e-03 -0.269000 1.78e-02
Signaling by Hedgehog 116 4.17e-03 -0.154000 1.79e-02
Negative regulation of FGFR1 signaling 22 4.24e-03 -0.352000 1.81e-02
Phase I - Functionalization of compounds 74 4.26e-03 0.192000 1.81e-02
Processive synthesis on the C-strand of the telomere 19 4.50e-03 0.377000 1.91e-02
Processing of DNA double-strand break ends 62 4.76e-03 0.207000 2.02e-02
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 18 4.86e-03 -0.383000 2.04e-02
Signaling by Ligand-Responsive EGFR Variants in Cancer 18 4.86e-03 -0.383000 2.04e-02
CDT1 association with the CDC6:ORC:origin complex 56 4.88e-03 -0.218000 2.04e-02
Signaling by FGFR3 32 4.89e-03 -0.288000 2.04e-02
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 31 4.90e-03 -0.292000 2.04e-02
RND2 GTPase cycle 37 5.03e-03 -0.267000 2.09e-02
Organelle biogenesis and maintenance 243 5.10e-03 0.105000 2.12e-02
Negative regulation of FGFR4 signaling 21 5.12e-03 -0.353000 2.12e-02
Post-translational modification: synthesis of GPI-anchored proteins 48 5.19e-03 0.233000 2.13e-02
Antigen processing-Cross presentation 87 5.21e-03 -0.173000 2.13e-02
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 49 5.23e-03 -0.231000 2.13e-02
p53-Independent DNA Damage Response 49 5.23e-03 -0.231000 2.13e-02
p53-Independent G1/S DNA damage checkpoint 49 5.23e-03 -0.231000 2.13e-02
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 68 5.41e-03 -0.195000 2.20e-02
p53-Dependent G1 DNA Damage Response 62 5.64e-03 -0.203000 2.27e-02
p53-Dependent G1/S DNA damage checkpoint 62 5.64e-03 -0.203000 2.27e-02
Inactivation of APC/C via direct inhibition of the APC/C complex 21 5.65e-03 0.349000 2.27e-02
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 21 5.65e-03 0.349000 2.27e-02
Cytosolic sensors of pathogen-associated DNA 53 5.67e-03 -0.220000 2.27e-02
Regulation of signaling by CBL 14 6.41e-03 -0.421000 2.56e-02
Scavenging by Class A Receptors 11 6.71e-03 -0.472000 2.67e-02
RHOBTB2 GTPase cycle 23 6.85e-03 -0.326000 2.72e-02
Attenuation phase 21 7.27e-03 -0.338000 2.88e-02
Intra-Golgi traffic 40 7.32e-03 -0.245000 2.89e-02
Antigen processing: Ubiquitination & Proteasome degradation 279 7.42e-03 -0.093400 2.92e-02
PERK regulates gene expression 31 7.50e-03 -0.278000 2.94e-02
RHOC GTPase cycle 67 7.55e-03 -0.189000 2.95e-02
Defective pyroptosis 13 7.60e-03 0.428000 2.96e-02
Nephrin family interactions 17 7.65e-03 -0.374000 2.97e-02
RIP-mediated NFkB activation via ZBP1 14 7.78e-03 -0.411000 3.02e-02
RUNX3 regulates p14-ARF 10 7.93e-03 -0.485000 3.07e-02
SCF(Skp2)-mediated degradation of p27/p21 58 7.96e-03 -0.202000 3.07e-02
Carboxyterminal post-translational modifications of tubulin 30 8.12e-03 0.279000 3.10e-02
FCGR3A-mediated phagocytosis 47 8.13e-03 -0.223000 3.10e-02
Leishmania phagocytosis 47 8.13e-03 -0.223000 3.10e-02
Parasite infection 47 8.13e-03 -0.223000 3.10e-02
Activated NOTCH1 Transmits Signal to the Nucleus 25 8.25e-03 -0.305000 3.14e-02
RHOA GTPase cycle 129 8.29e-03 -0.135000 3.14e-02
Suppression of phagosomal maturation 12 8.36e-03 -0.440000 3.16e-02
RHOJ GTPase cycle 49 8.57e-03 -0.217000 3.23e-02
Ethanol oxidation 10 8.67e-03 0.479000 3.25e-02
Integrin cell surface interactions 45 8.68e-03 0.226000 3.25e-02
RHOB GTPase cycle 63 8.68e-03 -0.191000 3.25e-02
Insulin receptor signalling cascade 37 8.80e-03 -0.249000 3.28e-02
Cellular response to heat stress 91 9.35e-03 -0.158000 3.48e-02
ATF6 (ATF6-alpha) activates chaperone genes 10 9.43e-03 -0.474000 3.50e-02
ERK/MAPK targets 21 9.53e-03 -0.327000 3.53e-02
FOXO-mediated transcription 52 9.66e-03 -0.208000 3.57e-02
Signaling by FGFR1 38 9.69e-03 -0.243000 3.57e-02
Interleukin-12 family signaling 46 9.79e-03 -0.220000 3.59e-02
Sphingolipid metabolism 77 9.83e-03 -0.170000 3.59e-02
M Phase 339 9.84e-03 0.081900 3.59e-02
Regulation of PLK1 Activity at G2/M Transition 84 9.91e-03 0.163000 3.61e-02
Peroxisomal lipid metabolism 26 9.99e-03 0.292000 3.63e-02
RET signaling 34 1.05e-02 -0.254000 3.79e-02
CDC42 GTPase cycle 130 1.05e-02 -0.130000 3.79e-02
CD28 co-stimulation 26 1.07e-02 -0.289000 3.85e-02
TRAF6 mediated NF-kB activation 22 1.08e-02 -0.314000 3.89e-02
Signaling by FGFR 69 1.09e-02 -0.177000 3.93e-02
ATF6 (ATF6-alpha) activates chaperones 12 1.10e-02 -0.424000 3.93e-02
Incretin synthesis, secretion, and inactivation 13 1.10e-02 -0.407000 3.93e-02
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 16 1.12e-02 -0.366000 3.99e-02
NF-kB is activated and signals survival 12 1.14e-02 -0.422000 4.04e-02
Asymmetric localization of PCP proteins 58 1.14e-02 -0.192000 4.04e-02
MET activates RAS signaling 10 1.15e-02 -0.461000 4.07e-02
ZBP1(DAI) mediated induction of type I IFNs 17 1.21e-02 -0.352000 4.26e-02
Glyoxylate metabolism and glycine degradation 27 1.22e-02 0.279000 4.27e-02
Negative regulation of FGFR3 signaling 21 1.24e-02 -0.315000 4.34e-02
Signaling by MET 63 1.24e-02 -0.182000 4.34e-02
Negative regulation of MET activity 18 1.25e-02 -0.340000 4.37e-02
FLT3 Signaling 32 1.26e-02 -0.255000 4.38e-02
Common Pathway of Fibrin Clot Formation 16 1.26e-02 0.360000 4.39e-02
Death Receptor Signalling 124 1.27e-02 -0.130000 4.41e-02
CD28 dependent PI3K/Akt signaling 18 1.32e-02 -0.337000 4.55e-02
LDL clearance 19 1.32e-02 -0.328000 4.55e-02
p75 NTR receptor-mediated signalling 82 1.34e-02 -0.158000 4.61e-02
ERKs are inactivated 13 1.35e-02 -0.396000 4.61e-02
Constitutive Signaling by AKT1 E17K in Cancer 24 1.35e-02 -0.291000 4.62e-02
Signaling by ALK fusions and activated point mutants 50 1.38e-02 -0.201000 4.70e-02
Signaling by ALK in cancer 50 1.38e-02 -0.201000 4.70e-02
Metabolism of vitamins and cofactors 160 1.40e-02 0.113000 4.76e-02
HSF1-dependent transactivation 30 1.44e-02 -0.258000 4.86e-02
Semaphorin interactions 51 1.44e-02 -0.198000 4.86e-02
Constitutive Signaling by EGFRvIII 14 1.47e-02 -0.377000 4.94e-02
Signaling by EGFRvIII in Cancer 14 1.47e-02 -0.377000 4.94e-02
Regulation of PTEN gene transcription 58 1.48e-02 -0.185000 4.95e-02
Spry regulation of FGF signaling 16 1.48e-02 -0.352000 4.95e-02
Post-chaperonin tubulin folding pathway 17 1.49e-02 0.341000 4.95e-02
Degradation of cysteine and homocysteine 12 1.51e-02 0.405000 5.03e-02
rRNA processing in the mitochondrion 21 1.53e-02 0.306000 5.04e-02
RAF activation 33 1.54e-02 -0.244000 5.04e-02
G1/S DNA Damage Checkpoints 64 1.54e-02 -0.175000 5.04e-02
Programmed Cell Death 177 1.54e-02 -0.106000 5.04e-02
Mitochondrial tRNA aminoacylation 18 1.54e-02 0.330000 5.04e-02
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 49 1.55e-02 -0.200000 5.04e-02
Constitutive Signaling by NOTCH1 PEST Domain Mutants 49 1.55e-02 -0.200000 5.04e-02
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 49 1.55e-02 -0.200000 5.04e-02
Signaling by NOTCH1 PEST Domain Mutants in Cancer 49 1.55e-02 -0.200000 5.04e-02
Signaling by NOTCH1 in Cancer 49 1.55e-02 -0.200000 5.04e-02
RHOH GTPase cycle 32 1.58e-02 -0.247000 5.12e-02
FCERI mediated MAPK activation 25 1.58e-02 -0.279000 5.12e-02
Signaling by Nuclear Receptors 197 1.59e-02 -0.099800 5.14e-02
mTORC1-mediated signalling 24 1.60e-02 -0.284000 5.14e-02
RHOBTB1 GTPase cycle 21 1.60e-02 -0.304000 5.15e-02
Constitutive Signaling by Aberrant PI3K in Cancer 43 1.61e-02 -0.212000 5.15e-02
Synthesis of PIPs at the plasma membrane 45 1.61e-02 -0.207000 5.15e-02
Telomere C-strand synthesis initiation 13 1.61e-02 0.385000 5.15e-02
RHOF GTPase cycle 40 1.63e-02 -0.220000 5.20e-02
Effects of PIP2 hydrolysis 18 1.69e-02 -0.325000 5.36e-02
Meiosis 46 1.70e-02 0.204000 5.36e-02
Signalling to RAS 18 1.70e-02 -0.325000 5.36e-02
SHC1 events in EGFR signaling 11 1.70e-02 -0.416000 5.36e-02
ER-Phagosome pathway 79 1.73e-02 -0.155000 5.43e-02
MTOR signalling 40 1.74e-02 -0.217000 5.45e-02
Ovarian tumor domain proteases 36 1.81e-02 -0.228000 5.66e-02
Cyclin E associated events during G1/S transition 80 1.87e-02 -0.152000 5.83e-02
Neddylation 214 1.91e-02 -0.093200 5.95e-02
Prolonged ERK activation events 12 1.93e-02 -0.390000 5.98e-02
Phosphorylation of the APC/C 20 1.93e-02 0.302000 5.98e-02
p75NTR signals via NF-kB 15 2.00e-02 -0.347000 6.18e-02
tRNA processing in the mitochondrion 17 2.04e-02 0.325000 6.29e-02
Metabolism 1696 2.04e-02 0.034600 6.29e-02
Removal of the Flap Intermediate from the C-strand 17 2.08e-02 0.324000 6.40e-02
Tie2 Signaling 14 2.13e-02 -0.355000 6.52e-02
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 10 2.13e-02 -0.420000 6.52e-02
Rab regulation of trafficking 114 2.14e-02 -0.125000 6.52e-02
Sphingolipid de novo biosynthesis 38 2.14e-02 -0.216000 6.53e-02
NOTCH1 Intracellular Domain Regulates Transcription 42 2.17e-02 -0.205000 6.59e-02
HDACs deacetylate histones 32 2.21e-02 -0.234000 6.70e-02
Metabolism of water-soluble vitamins and cofactors 104 2.21e-02 0.130000 6.70e-02
HDR through MMEJ (alt-NHEJ) 10 2.23e-02 0.417000 6.75e-02
Signaling by FGFR2 57 2.24e-02 -0.175000 6.75e-02
Pausing and recovery of Tat-mediated HIV elongation 30 2.34e-02 -0.239000 7.02e-02
Tat-mediated HIV elongation arrest and recovery 30 2.34e-02 -0.239000 7.02e-02
Costimulation by the CD28 family 41 2.36e-02 -0.204000 7.07e-02
Regulation of BACH1 activity 11 2.40e-02 -0.393000 7.15e-02
Formation of RNA Pol II elongation complex 57 2.40e-02 -0.173000 7.15e-02
RNA Polymerase II Transcription Elongation 57 2.40e-02 -0.173000 7.15e-02
DAP12 signaling 21 2.41e-02 -0.284000 7.15e-02
Regulation of HSF1-mediated heat shock response 74 2.42e-02 -0.152000 7.18e-02
Nicotinate metabolism 23 2.46e-02 0.271000 7.28e-02
Regulation of TP53 Activity through Phosphorylation 88 2.48e-02 0.139000 7.32e-02
Resolution of AP sites via the multiple-nucleotide patch replacement pathway 24 2.50e-02 0.264000 7.35e-02
Mitochondrial Fatty Acid Beta-Oxidation 32 2.54e-02 0.228000 7.47e-02
G1/S-Specific Transcription 28 2.62e-02 0.243000 7.67e-02
Estrogen-dependent nuclear events downstream of ESR-membrane signaling 20 2.66e-02 -0.286000 7.79e-02
SLC-mediated transmembrane transport 174 2.71e-02 -0.097300 7.91e-02
E2F mediated regulation of DNA replication 22 2.72e-02 0.272000 7.92e-02
Nicotinamide salvaging 14 2.74e-02 0.341000 7.96e-02
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) 12 2.79e-02 -0.367000 8.09e-02
Signaling by ERBB2 42 2.82e-02 -0.196000 8.17e-02
Selective autophagy 56 2.85e-02 -0.169000 8.24e-02
Methylation 12 2.86e-02 0.365000 8.24e-02
APC-Cdc20 mediated degradation of Nek2A 26 2.93e-02 0.247000 8.41e-02
Constitutive Signaling by NOTCH1 HD Domain Mutants 12 2.96e-02 -0.363000 8.46e-02
Signaling by NOTCH1 HD Domain Mutants in Cancer 12 2.96e-02 -0.363000 8.46e-02
RHO GTPases Activate Formins 116 2.96e-02 0.117000 8.46e-02
RND1 GTPase cycle 37 2.99e-02 -0.206000 8.52e-02
Mitophagy 27 3.00e-02 -0.241000 8.53e-02
DARPP-32 events 20 3.01e-02 -0.280000 8.54e-02
Formation of TC-NER Pre-Incision Complex 53 3.06e-02 -0.172000 8.67e-02
Cyclin A:Cdk2-associated events at S phase entry 82 3.09e-02 -0.138000 8.72e-02
TAK1 activates NFkB by phosphorylation and activation of IKKs complex 24 3.10e-02 -0.254000 8.75e-02
Transcriptional Regulation by TP53 351 3.11e-02 -0.067200 8.76e-02
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein 64 3.17e-02 -0.155000 8.92e-02
Polo-like kinase mediated events 16 3.26e-02 0.309000 9.14e-02
Advanced glycosylation endproduct receptor signaling 10 3.27e-02 -0.390000 9.14e-02
Kinesins 37 3.28e-02 0.203000 9.15e-02
IGF1R signaling cascade 35 3.29e-02 -0.208000 9.17e-02
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 35 3.29e-02 -0.208000 9.17e-02
Assembly of active LPL and LIPC lipase complexes 16 3.33e-02 0.307000 9.22e-02
Signaling by NOTCH3 37 3.33e-02 -0.202000 9.22e-02
L1CAM interactions 72 3.33e-02 -0.145000 9.22e-02
Cyclin A/B1/B2 associated events during G2/M transition 24 3.35e-02 0.251000 9.24e-02
EPHB-mediated forward signaling 34 3.38e-02 -0.210000 9.30e-02
EGR2 and SOX10-mediated initiation of Schwann cell myelination 23 3.40e-02 0.255000 9.34e-02
IRS-mediated signalling 32 3.41e-02 -0.216000 9.36e-02
APC truncation mutants have impaired AXIN binding 14 3.57e-02 -0.324000 9.66e-02
AXIN missense mutants destabilize the destruction complex 14 3.57e-02 -0.324000 9.66e-02
Signaling by AMER1 mutants 14 3.57e-02 -0.324000 9.66e-02
Signaling by APC mutants 14 3.57e-02 -0.324000 9.66e-02
Signaling by AXIN mutants 14 3.57e-02 -0.324000 9.66e-02
Truncations of AMER1 destabilize the destruction complex 14 3.57e-02 -0.324000 9.66e-02
HATs acetylate histones 78 3.57e-02 -0.138000 9.66e-02
RHOD GTPase cycle 49 3.58e-02 -0.173000 9.66e-02
DNA Replication 127 3.66e-02 0.108000 9.86e-02
Defective EXT1 causes exostoses 1, TRPS2 and CHDS 13 3.71e-02 0.334000 9.96e-02
Defective EXT2 causes exostoses 2 13 3.71e-02 0.334000 9.96e-02
Negative regulation of FGFR2 signaling 21 3.72e-02 -0.263000 9.98e-02
Aberrant regulation of mitotic exit in cancer due to RB1 defects 20 3.74e-02 0.269000 1.00e-01
Signaling by PDGFR in disease 17 3.76e-02 -0.291000 1.00e-01
RHO GTPases Activate WASPs and WAVEs 32 3.76e-02 -0.212000 1.00e-01
HIV elongation arrest and recovery 32 3.78e-02 -0.212000 1.00e-01
Pausing and recovery of HIV elongation 32 3.78e-02 -0.212000 1.00e-01
Diseases of mitotic cell cycle 37 3.79e-02 0.197000 1.00e-01
Trafficking and processing of endosomal TLR 10 3.80e-02 -0.379000 1.00e-01
Phospholipid metabolism 160 3.81e-02 -0.095200 1.00e-01
Sulfur amino acid metabolism 26 3.87e-02 0.234000 1.02e-01
RHOU GTPase cycle 36 3.97e-02 -0.198000 1.04e-01
SUMOylation of intracellular receptors 25 3.99e-02 -0.237000 1.05e-01
Cleavage of the damaged purine 11 4.01e-02 0.357000 1.05e-01
Depurination 11 4.01e-02 0.357000 1.05e-01
Recognition and association of DNA glycosylase with site containing an affected purine 11 4.01e-02 0.357000 1.05e-01
Platelet activation, signaling and aggregation 189 4.04e-02 -0.086600 1.05e-01
G2/M Checkpoints 130 4.06e-02 0.104000 1.05e-01
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 20 4.06e-02 0.264000 1.05e-01
Translation of Structural Proteins 27 4.15e-02 -0.227000 1.07e-01
Collagen biosynthesis and modifying enzymes 36 4.16e-02 0.196000 1.08e-01
RNA Polymerase III Abortive And Retractive Initiation 41 4.20e-02 -0.184000 1.08e-01
RNA Polymerase III Transcription 41 4.20e-02 -0.184000 1.08e-01
FCERI mediated Ca+2 mobilization 20 4.23e-02 -0.262000 1.09e-01
Defective B4GALT7 causes EDS, progeroid type 14 4.47e-02 0.310000 1.15e-01
PINK1-PRKN Mediated Mitophagy 20 4.53e-02 -0.259000 1.16e-01
Negative regulation of FLT3 13 4.58e-02 -0.320000 1.17e-01
Diseases associated with N-glycosylation of proteins 17 4.60e-02 -0.280000 1.17e-01
Antimicrobial peptides 17 4.65e-02 0.279000 1.18e-01
GPCR downstream signalling 257 4.72e-02 -0.072100 1.20e-01
Reproduction 56 4.72e-02 0.153000 1.20e-01
Downregulation of SMAD2/3:SMAD4 transcriptional activity 27 4.77e-02 -0.220000 1.21e-01
Cytosolic sulfonation of small molecules 20 4.81e-02 0.255000 1.21e-01
Plasma lipoprotein clearance 32 4.84e-02 -0.202000 1.22e-01
Assembly Of The HIV Virion 16 4.84e-02 -0.285000 1.22e-01
Energy dependent regulation of mTOR by LKB1-AMPK 28 4.85e-02 -0.216000 1.22e-01
GRB2 events in EGFR signaling 10 4.86e-02 -0.360000 1.22e-01
FLT3 signaling in disease 26 4.88e-02 -0.223000 1.22e-01
Metabolism of amino acids and derivatives 315 4.88e-02 -0.064800 1.22e-01
Miscellaneous transport and binding events 21 4.90e-02 -0.248000 1.22e-01
ALK mutants bind TKIs 10 4.92e-02 -0.359000 1.23e-01
PI3K Cascade 28 4.98e-02 -0.214000 1.24e-01
RNA Polymerase III Transcription Termination 23 5.01e-02 -0.236000 1.24e-01
DDX58/IFIH1-mediated induction of interferon-alpha/beta 64 5.02e-02 -0.142000 1.24e-01
MHC class II antigen presentation 84 5.02e-02 -0.124000 1.24e-01
Condensation of Prometaphase Chromosomes 11 5.03e-02 0.341000 1.24e-01
SHC-mediated cascade:FGFR4 10 5.07e-02 -0.357000 1.25e-01
Synthesis of DNA 116 5.08e-02 0.105000 1.25e-01
tRNA Aminoacylation 24 5.18e-02 0.229000 1.27e-01
RNA Polymerase III Transcription Initiation From Type 1 Promoter 28 5.21e-02 -0.212000 1.28e-01
Cell recruitment (pro-inflammatory response) 19 5.28e-02 0.257000 1.29e-01
Purinergic signaling in leishmaniasis infection 19 5.28e-02 0.257000 1.29e-01
Activation of HOX genes during differentiation 52 5.31e-02 -0.155000 1.29e-01
Activation of anterior HOX genes in hindbrain development during early embryogenesis 52 5.31e-02 -0.155000 1.29e-01
Basigin interactions 20 5.37e-02 -0.249000 1.30e-01
FOXO-mediated transcription of cell death genes 15 5.49e-02 -0.286000 1.33e-01
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand 31 5.52e-02 -0.199000 1.34e-01
Erythropoietin activates RAS 13 5.53e-02 -0.307000 1.34e-01
Lysine catabolism 12 5.56e-02 0.319000 1.34e-01
Role of LAT2/NTAL/LAB on calcium mobilization 12 5.70e-02 -0.317000 1.37e-01
Synthesis of substrates in N-glycan biosythesis 49 5.77e-02 -0.157000 1.38e-01
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 23 5.77e-02 -0.229000 1.38e-01
SHC-mediated cascade:FGFR1 10 5.78e-02 -0.346000 1.38e-01
Intrinsic Pathway of Fibrin Clot Formation 18 5.80e-02 0.258000 1.38e-01
Estrogen-dependent gene expression 84 5.80e-02 -0.120000 1.38e-01
Aberrant regulation of mitotic cell cycle due to RB1 defects 35 5.81e-02 0.185000 1.38e-01
RNA Polymerase II Pre-transcription Events 78 5.82e-02 -0.124000 1.38e-01
Disassembly of the destruction complex and recruitment of AXIN to the membrane 25 5.95e-02 -0.218000 1.41e-01
FOXO-mediated transcription of cell cycle genes 14 5.95e-02 -0.291000 1.41e-01
Activation of BAD and translocation to mitochondria 14 5.98e-02 -0.291000 1.41e-01
PKMTs methylate histone lysines 41 6.02e-02 -0.170000 1.42e-01
InlB-mediated entry of Listeria monocytogenes into host cell 13 6.02e-02 -0.301000 1.42e-01
GPVI-mediated activation cascade 22 6.03e-02 -0.231000 1.42e-01
Hedgehog ‘off’ state 86 6.06e-02 -0.117000 1.42e-01
Signaling by ERBB4 42 6.06e-02 -0.167000 1.42e-01
IRS-related events triggered by IGF1R 34 6.07e-02 -0.186000 1.42e-01
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 18 6.08e-02 -0.255000 1.42e-01
Downstream signaling of activated FGFR4 17 6.08e-02 -0.263000 1.42e-01
HS-GAG degradation 18 6.10e-02 0.255000 1.42e-01
CTLA4 inhibitory signaling 17 6.14e-02 -0.262000 1.43e-01
Metabolism of nucleotides 86 6.19e-02 0.117000 1.44e-01
Vitamin B5 (pantothenate) metabolism 16 6.20e-02 0.270000 1.44e-01
Constitutive Signaling by Overexpressed ERBB2 11 6.33e-02 -0.323000 1.46e-01
TICAM1-dependent activation of IRF3/IRF7 10 6.40e-02 -0.338000 1.48e-01
Striated Muscle Contraction 18 6.54e-02 0.251000 1.51e-01
Pexophagy 11 6.55e-02 -0.321000 1.51e-01
Glutathione synthesis and recycling 12 6.59e-02 0.307000 1.51e-01
S33 mutants of beta-catenin aren’t phosphorylated 15 6.65e-02 -0.274000 1.51e-01
S37 mutants of beta-catenin aren’t phosphorylated 15 6.65e-02 -0.274000 1.51e-01
S45 mutants of beta-catenin aren’t phosphorylated 15 6.65e-02 -0.274000 1.51e-01
Signaling by CTNNB1 phospho-site mutants 15 6.65e-02 -0.274000 1.51e-01
Signaling by GSK3beta mutants 15 6.65e-02 -0.274000 1.51e-01
T41 mutants of beta-catenin aren’t phosphorylated 15 6.65e-02 -0.274000 1.51e-01
NOTCH3 Activation and Transmission of Signal to the Nucleus 21 6.67e-02 -0.231000 1.52e-01
Gastrin-CREB signalling pathway via PKC and MAPK 16 6.80e-02 -0.264000 1.54e-01
Recycling pathway of L1 24 6.86e-02 -0.215000 1.55e-01
Signaling by ERBB2 ECD mutants 15 6.95e-02 -0.271000 1.57e-01
WNT5A-dependent internalization of FZD4 12 7.08e-02 -0.301000 1.60e-01
Fatty acyl-CoA biosynthesis 29 7.11e-02 0.194000 1.60e-01
Deadenylation of mRNA 24 7.24e-02 -0.212000 1.63e-01
Metabolism of steroids 130 7.27e-02 0.091300 1.63e-01
HSF1 activation 24 7.33e-02 -0.211000 1.64e-01
Autodegradation of Cdh1 by Cdh1:APC/C 63 7.39e-02 -0.130000 1.65e-01
Signal transduction by L1 18 7.41e-02 -0.243000 1.65e-01
PCNA-Dependent Long Patch Base Excision Repair 21 7.41e-02 0.225000 1.65e-01
CDK-mediated phosphorylation and removal of Cdc6 69 7.48e-02 -0.124000 1.67e-01
RAF-independent MAPK1/3 activation 21 7.79e-02 -0.222000 1.73e-01
SHC1 events in ERBB2 signaling 15 7.86e-02 -0.262000 1.74e-01
CD209 (DC-SIGN) signaling 18 7.96e-02 -0.239000 1.76e-01
Keratinization 29 8.01e-02 -0.188000 1.77e-01
Signaling by ERBB2 in Cancer 19 8.02e-02 -0.232000 1.77e-01
Cytochrome P450 - arranged by substrate type 44 8.11e-02 0.152000 1.79e-01
Synthesis of PA 25 8.13e-02 0.201000 1.79e-01
Assembly of collagen fibrils and other multimeric structures 34 8.13e-02 0.173000 1.79e-01
TICAM1, RIP1-mediated IKK complex recruitment 17 8.17e-02 -0.244000 1.79e-01
Gap-filling DNA repair synthesis and ligation in GG-NER 25 8.18e-02 0.201000 1.79e-01
PI-3K cascade:FGFR4 10 8.22e-02 -0.317000 1.80e-01
SUMOylation of transcription cofactors 43 8.25e-02 -0.153000 1.80e-01
S Phase 157 8.27e-02 0.080400 1.81e-01
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 45 8.32e-02 -0.149000 1.81e-01
Golgi-to-ER retrograde transport 106 8.47e-02 -0.097000 1.84e-01
Beta-catenin phosphorylation cascade 17 8.52e-02 -0.241000 1.85e-01
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins 10 8.67e-02 0.313000 1.88e-01
p75NTR recruits signalling complexes 12 8.71e-02 -0.285000 1.89e-01
Peptide hormone metabolism 50 8.72e-02 -0.140000 1.89e-01
Synthesis of PIPs at the early endosome membrane 15 8.82e-02 -0.254000 1.90e-01
Generation of second messenger molecules 14 8.83e-02 -0.263000 1.90e-01
RNA Polymerase III Transcription Initiation From Type 2 Promoter 27 8.88e-02 -0.189000 1.91e-01
Formation of Incision Complex in GG-NER 43 8.95e-02 0.150000 1.92e-01
N-glycan antennae elongation in the medial/trans-Golgi 19 9.13e-02 -0.224000 1.96e-01
CDC6 association with the ORC:origin complex 11 9.19e-02 0.293000 1.97e-01
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function 34 9.21e-02 -0.167000 1.97e-01
Repression of WNT target genes 12 9.21e-02 -0.281000 1.97e-01
GPCR ligand binding 128 9.25e-02 0.086200 1.97e-01
PI-3K cascade:FGFR1 10 9.28e-02 -0.307000 1.97e-01
RORA activates gene expression 18 9.32e-02 -0.229000 1.98e-01
WNT ligand biogenesis and trafficking 11 9.34e-02 -0.292000 1.98e-01
Transport of vitamins, nucleosides, and related molecules 33 9.36e-02 0.169000 1.98e-01
Protein-protein interactions at synapses 52 9.40e-02 0.134000 1.99e-01
HS-GAG biosynthesis 22 9.43e-02 0.206000 1.99e-01
Cell-Cell communication 90 9.47e-02 -0.102000 2.00e-01
Signaling by PDGFRA extracellular domain mutants 11 9.60e-02 -0.290000 2.02e-01
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants 11 9.60e-02 -0.290000 2.02e-01
Frs2-mediated activation 10 9.64e-02 -0.304000 2.02e-01
Positive epigenetic regulation of rRNA expression 44 9.68e-02 -0.145000 2.03e-01
Hemostasis 409 9.69e-02 -0.048100 2.03e-01
Oncogenic MAPK signaling 72 9.76e-02 -0.113000 2.04e-01
DAP12 interactions 24 9.89e-02 -0.195000 2.06e-01
Signaling by Erythropoietin 22 9.92e-02 -0.203000 2.07e-01
Acyl chain remodelling of PC 11 1.00e-01 0.286000 2.09e-01
Defects in cobalamin (B12) metabolism 12 1.01e-01 0.273000 2.10e-01
Signaling by GPCR 289 1.01e-01 -0.056200 2.10e-01
Translation of Replicase and Assembly of the Replication Transcription Complex 13 1.02e-01 -0.262000 2.12e-01
Mitotic Anaphase 221 1.03e-01 0.063900 2.12e-01
Signaling by FLT3 ITD and TKD mutants 14 1.07e-01 -0.249000 2.20e-01
Termination of translesion DNA synthesis 32 1.07e-01 0.165000 2.20e-01
Insulin processing 22 1.07e-01 -0.199000 2.20e-01
Chaperone Mediated Autophagy 17 1.08e-01 -0.225000 2.22e-01
Separation of Sister Chromatids 165 1.08e-01 0.072600 2.22e-01
APC/C:Cdc20 mediated degradation of Securin 65 1.08e-01 -0.115000 2.22e-01
COPI-dependent Golgi-to-ER retrograde traffic 75 1.09e-01 -0.107000 2.22e-01
ATF4 activates genes in response to endoplasmic reticulum stress 26 1.09e-01 -0.182000 2.22e-01
ABC transporters in lipid homeostasis 14 1.09e-01 0.248000 2.22e-01
Disorders of Developmental Biology 12 1.12e-01 -0.265000 2.26e-01
Disorders of Nervous System Development 12 1.12e-01 -0.265000 2.26e-01
Loss of function of MECP2 in Rett syndrome 12 1.12e-01 -0.265000 2.26e-01
Pervasive developmental disorders 12 1.12e-01 -0.265000 2.26e-01
APC/C:Cdc20 mediated degradation of Cyclin B 24 1.12e-01 0.188000 2.26e-01
Signaling by FGFR3 fusions in cancer 10 1.12e-01 -0.290000 2.26e-01
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 33 1.12e-01 -0.160000 2.26e-01
Mitochondrial biogenesis 71 1.14e-01 -0.108000 2.30e-01
Metabolic disorders of biological oxidation enzymes 27 1.14e-01 0.176000 2.30e-01
Cardiac conduction 66 1.15e-01 -0.112000 2.32e-01
Mitotic Metaphase and Anaphase 222 1.15e-01 0.061500 2.32e-01
mRNA 3’-end processing 56 1.16e-01 -0.121000 2.33e-01
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 11 1.17e-01 -0.273000 2.35e-01
RNA Polymerase II Transcription Termination 65 1.18e-01 -0.112000 2.35e-01
G0 and Early G1 26 1.19e-01 0.177000 2.38e-01
Interleukin-3, Interleukin-5 and GM-CSF signaling 29 1.19e-01 -0.167000 2.38e-01
A tetrasaccharide linker sequence is required for GAG synthesis 18 1.20e-01 0.212000 2.39e-01
Late Phase of HIV Life Cycle 132 1.21e-01 -0.078300 2.40e-01
Myogenesis 19 1.21e-01 -0.206000 2.40e-01
Regulation of IFNA signaling 12 1.21e-01 0.258000 2.40e-01
Extracellular matrix organization 183 1.22e-01 0.066500 2.40e-01
Downstream signal transduction 28 1.22e-01 -0.169000 2.40e-01
Biotin transport and metabolism 11 1.22e-01 -0.269000 2.40e-01
Formation of HIV-1 elongation complex containing HIV-1 Tat 42 1.22e-01 -0.138000 2.41e-01
HIV Transcription Elongation 42 1.22e-01 -0.138000 2.41e-01
Tat-mediated elongation of the HIV-1 transcript 42 1.22e-01 -0.138000 2.41e-01
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 14 1.23e-01 -0.238000 2.41e-01
Downstream signaling of activated FGFR3 17 1.23e-01 -0.216000 2.41e-01
Defective B3GAT3 causes JDSSDHD 14 1.23e-01 0.238000 2.41e-01
G alpha (q) signalling events 93 1.23e-01 -0.092500 2.41e-01
RHO GTPases activate PAKs 20 1.24e-01 -0.199000 2.42e-01
Neurexins and neuroligins 36 1.24e-01 0.148000 2.42e-01
IKK complex recruitment mediated by RIP1 20 1.25e-01 -0.198000 2.43e-01
Diseases associated with glycosaminoglycan metabolism 29 1.25e-01 0.164000 2.44e-01
B-WICH complex positively regulates rRNA expression 29 1.26e-01 -0.164000 2.45e-01
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 16 1.27e-01 0.221000 2.45e-01
Retinoid metabolism and transport 35 1.28e-01 0.149000 2.48e-01
SHC-mediated cascade:FGFR3 10 1.28e-01 -0.278000 2.48e-01
Arachidonic acid metabolism 30 1.31e-01 0.160000 2.52e-01
Assembly of the pre-replicative complex 69 1.32e-01 -0.105000 2.55e-01
FRS-mediated FGFR4 signaling 12 1.34e-01 -0.250000 2.57e-01
Binding and Uptake of Ligands by Scavenger Receptors 27 1.34e-01 -0.167000 2.57e-01
Netrin-1 signaling 35 1.34e-01 -0.146000 2.58e-01
Abortive elongation of HIV-1 transcript in the absence of Tat 23 1.34e-01 -0.180000 2.58e-01
Formation of the beta-catenin:TCF transactivating complex 30 1.35e-01 -0.158000 2.58e-01
Signaling by ERBB2 KD Mutants 18 1.36e-01 -0.203000 2.60e-01
SUMOylation of immune response proteins 11 1.37e-01 -0.259000 2.61e-01
Interleukin receptor SHC signaling 17 1.38e-01 -0.208000 2.62e-01
Heparan sulfate/heparin (HS-GAG) metabolism 36 1.38e-01 0.143000 2.63e-01
MECP2 regulates neuronal receptors and channels 13 1.39e-01 -0.237000 2.64e-01
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism 12 1.39e-01 0.246000 2.64e-01
alpha-linolenic acid (ALA) metabolism 12 1.39e-01 0.246000 2.64e-01
Regulation of TNFR1 signaling 34 1.39e-01 -0.147000 2.64e-01
Elastic fibre formation 28 1.43e-01 0.160000 2.69e-01
Signaling by FGFR4 in disease 11 1.45e-01 -0.254000 2.73e-01
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 10 1.45e-01 -0.266000 2.73e-01
Plasma lipoprotein remodeling 29 1.46e-01 0.156000 2.75e-01
GABA synthesis, release, reuptake and degradation 11 1.47e-01 -0.253000 2.76e-01
Ephrin signaling 15 1.48e-01 -0.216000 2.76e-01
FRS-mediated FGFR1 signaling 12 1.48e-01 -0.241000 2.76e-01
MAP2K and MAPK activation 34 1.48e-01 -0.143000 2.77e-01
Endogenous sterols 22 1.49e-01 0.178000 2.77e-01
Pyrimidine salvage 10 1.49e-01 0.264000 2.78e-01
Dual Incision in GG-NER 41 1.50e-01 0.130000 2.79e-01
Defective B3GALT6 causes EDSP2 and SEMDJL1 14 1.51e-01 0.222000 2.81e-01
Signaling by high-kinase activity BRAF mutants 30 1.52e-01 -0.151000 2.82e-01
p38MAPK events 13 1.52e-01 -0.230000 2.82e-01
Global Genome Nucleotide Excision Repair (GG-NER) 84 1.52e-01 0.090500 2.82e-01
N-Glycan antennae elongation 12 1.52e-01 -0.239000 2.82e-01
Mitochondrial iron-sulfur cluster biogenesis 13 1.53e-01 0.229000 2.82e-01
IRAK1 recruits IKK complex 10 1.53e-01 -0.261000 2.82e-01
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 10 1.53e-01 -0.261000 2.82e-01
RNA Polymerase III Transcription Initiation 36 1.53e-01 -0.138000 2.82e-01
Epigenetic regulation of gene expression 85 1.53e-01 -0.089700 2.82e-01
Paradoxical activation of RAF signaling by kinase inactive BRAF 38 1.54e-01 -0.134000 2.82e-01
Signaling by RAS mutants 38 1.54e-01 -0.134000 2.82e-01
Signaling by moderate kinase activity BRAF mutants 38 1.54e-01 -0.134000 2.82e-01
Signaling downstream of RAS mutants 38 1.54e-01 -0.134000 2.82e-01
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 25 1.57e-01 -0.164000 2.86e-01
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 17 1.57e-01 -0.198000 2.87e-01
Formation of HIV elongation complex in the absence of HIV Tat 44 1.59e-01 -0.123000 2.89e-01
Platelet calcium homeostasis 15 1.59e-01 -0.210000 2.90e-01
activated TAK1 mediates p38 MAPK activation 18 1.62e-01 -0.190000 2.94e-01
Signaling by Non-Receptor Tyrosine Kinases 44 1.63e-01 -0.122000 2.95e-01
Signaling by PTK6 44 1.63e-01 -0.122000 2.95e-01
EPH-ephrin mediated repulsion of cells 38 1.64e-01 -0.131000 2.96e-01
Defective B3GALTL causes PpS 19 1.64e-01 0.184000 2.97e-01
Membrane binding and targetting of GAG proteins 14 1.66e-01 -0.214000 2.99e-01
Synthesis And Processing Of GAG, GAGPOL Polyproteins 14 1.66e-01 -0.214000 2.99e-01
Nucleotide salvage 20 1.66e-01 0.179000 2.99e-01
GAB1 signalosome 14 1.66e-01 -0.214000 2.99e-01
Transcriptional regulation of white adipocyte differentiation 74 1.67e-01 -0.092900 3.00e-01
Regulation of cholesterol biosynthesis by SREBP (SREBF) 54 1.67e-01 0.109000 3.00e-01
Transport of bile salts and organic acids, metal ions and amine compounds 58 1.70e-01 -0.104000 3.04e-01
Class A/1 (Rhodopsin-like receptors) 84 1.70e-01 0.086700 3.04e-01
Retrograde neurotrophin signalling 10 1.70e-01 -0.250000 3.04e-01
SUMOylation of DNA replication proteins 45 1.71e-01 0.118000 3.04e-01
Regulation of TP53 Activity through Methylation 19 1.75e-01 -0.180000 3.11e-01
Inhibition of replication initiation of damaged DNA by RB1/E2F1 13 1.76e-01 0.217000 3.13e-01
Glycosphingolipid metabolism 39 1.76e-01 -0.125000 3.13e-01
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 14 1.78e-01 -0.208000 3.16e-01
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) 11 1.80e-01 0.234000 3.18e-01
Diseases of hemostasis 11 1.80e-01 0.234000 3.18e-01
Leishmania infection 133 1.81e-01 -0.067300 3.20e-01
O-glycosylation of TSR domain-containing proteins 20 1.82e-01 0.172000 3.21e-01
RHO GTPases activate KTN1 11 1.82e-01 -0.232000 3.21e-01
MET promotes cell motility 27 1.84e-01 -0.148000 3.24e-01
Synthesis of bile acids and bile salts via 27-hydroxycholesterol 14 1.84e-01 -0.205000 3.24e-01
Diseases associated with the TLR signaling cascade 22 1.85e-01 0.163000 3.24e-01
Diseases of Immune System 22 1.85e-01 0.163000 3.24e-01
Budding and maturation of HIV virion 28 1.86e-01 -0.145000 3.25e-01
Receptor Mediated Mitophagy 10 1.86e-01 -0.242000 3.25e-01
Signaling by FGFR3 in disease 14 1.89e-01 -0.203000 3.29e-01
Signaling by FGFR3 point mutants in cancer 14 1.89e-01 -0.203000 3.29e-01
RHO GTPases Activate ROCKs 19 1.89e-01 -0.174000 3.29e-01
Regulation of gene expression by Hypoxia-inducible Factor 11 1.90e-01 -0.228000 3.30e-01
Phenylalanine and tyrosine metabolism 10 1.90e-01 0.239000 3.31e-01
Nucleotide biosynthesis 14 1.91e-01 0.202000 3.31e-01
Transport of Mature Transcript to Cytoplasm 80 1.92e-01 -0.084500 3.32e-01
PI-3K cascade:FGFR3 10 1.92e-01 -0.238000 3.32e-01
Transcriptional Regulation by VENTX 35 1.92e-01 0.127000 3.32e-01
Nuclear events stimulated by ALK signaling in cancer 17 1.92e-01 -0.183000 3.32e-01
Signaling by WNT in cancer 32 1.92e-01 -0.133000 3.32e-01
Glucagon-type ligand receptors 11 1.94e-01 0.226000 3.35e-01
Visual phototransduction 68 1.96e-01 0.090800 3.37e-01
Sensory Perception 134 1.97e-01 0.064600 3.39e-01
Organic cation/anion/zwitterion transport 11 1.98e-01 -0.224000 3.39e-01
Signaling by FLT3 fusion proteins 18 1.98e-01 -0.175000 3.40e-01
Cell death signalling via NRAGE, NRIF and NADE 65 1.99e-01 -0.092100 3.42e-01
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 13 2.00e-01 -0.205000 3.42e-01
Apoptotic cleavage of cellular proteins 31 2.01e-01 -0.133000 3.43e-01
Ion transport by P-type ATPases 36 2.04e-01 -0.122000 3.48e-01
Late endosomal microautophagy 29 2.04e-01 -0.136000 3.48e-01
VEGFR2 mediated vascular permeability 22 2.05e-01 -0.156000 3.48e-01
Glucagon signaling in metabolic regulation 19 2.05e-01 0.168000 3.48e-01
Carnitine metabolism 11 2.05e-01 0.220000 3.49e-01
Signaling by ERBB2 TMD/JMD mutants 15 2.06e-01 -0.189000 3.49e-01
Association of TriC/CCT with target proteins during biosynthesis 38 2.07e-01 -0.118000 3.51e-01
Opioid Signalling 60 2.08e-01 -0.093900 3.53e-01
TP53 Regulates Transcription of Caspase Activators and Caspases 11 2.10e-01 0.218000 3.54e-01
Transport of Mature mRNA derived from an Intron-Containing Transcript 71 2.10e-01 -0.086100 3.54e-01
Activation of BH3-only proteins 28 2.10e-01 -0.137000 3.54e-01
Cell junction organization 64 2.10e-01 -0.090600 3.54e-01
Regulation of gene expression in beta cells 13 2.11e-01 0.201000 3.54e-01
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13 2.11e-01 0.200000 3.55e-01
Diseases of programmed cell death 41 2.12e-01 0.113000 3.55e-01
Hyaluronan metabolism 13 2.13e-01 -0.199000 3.57e-01
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 17 2.14e-01 -0.174000 3.59e-01
The canonical retinoid cycle in rods (twilight vision) 16 2.15e-01 0.179000 3.59e-01
Synthesis of bile acids and bile salts 31 2.17e-01 -0.128000 3.63e-01
RAB geranylgeranylation 52 2.18e-01 -0.098900 3.63e-01
Synthesis of IP3 and IP4 in the cytosol 20 2.18e-01 -0.159000 3.64e-01
Orc1 removal from chromatin 67 2.24e-01 -0.085900 3.73e-01
Cobalamin (Cbl, vitamin B12) transport and metabolism 14 2.25e-01 0.187000 3.73e-01
Sema4D in semaphorin signaling 24 2.25e-01 -0.143000 3.73e-01
Mitochondrial translation 93 2.27e-01 -0.072600 3.75e-01
Glycolysis 65 2.27e-01 -0.086700 3.76e-01
Deactivation of the beta-catenin transactivating complex 38 2.30e-01 -0.113000 3.81e-01
Interleukin-20 family signaling 15 2.32e-01 0.178000 3.83e-01
Olfactory Signaling Pathway 14 2.33e-01 0.184000 3.85e-01
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 42 2.40e-01 0.105000 3.95e-01
HIV Life Cycle 143 2.42e-01 -0.056800 3.97e-01
Aggrephagy 20 2.42e-01 -0.151000 3.97e-01
Transcriptional regulation of granulopoiesis 25 2.42e-01 -0.135000 3.97e-01
Cell surface interactions at the vascular wall 86 2.42e-01 -0.073000 3.97e-01
RNA Polymerase III Chain Elongation 18 2.43e-01 -0.159000 3.97e-01
Antiviral mechanism by IFN-stimulated genes 77 2.44e-01 -0.076900 3.99e-01
Sensory perception of taste 13 2.45e-01 0.186000 3.99e-01
MicroRNA (miRNA) biogenesis 24 2.45e-01 -0.137000 3.99e-01
Chondroitin sulfate biosynthesis 14 2.45e-01 -0.180000 3.99e-01
Regulated proteolysis of p75NTR 11 2.46e-01 -0.202000 4.00e-01
NRAGE signals death through JNK 48 2.47e-01 -0.096700 4.01e-01
Transcriptional activation of mitochondrial biogenesis 50 2.50e-01 -0.094100 4.06e-01
TRAF6 mediated IRF7 activation 15 2.50e-01 -0.171000 4.06e-01
tRNA processing 114 2.53e-01 0.062100 4.09e-01
Keratan sulfate/keratin metabolism 25 2.53e-01 -0.132000 4.09e-01
Synthesis of bile acids and bile salts via 24-hydroxycholesterol 14 2.55e-01 -0.176000 4.12e-01
Mitochondrial translation termination 87 2.56e-01 -0.070500 4.14e-01
CLEC7A (Dectin-1) induces NFAT activation 10 2.57e-01 -0.207000 4.15e-01
Interferon alpha/beta signaling 45 2.57e-01 0.097600 4.15e-01
Synthesis of glycosylphosphatidylinositol (GPI) 18 2.58e-01 0.154000 4.15e-01
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 48 2.58e-01 -0.094400 4.15e-01
Signal regulatory protein family interactions 10 2.59e-01 0.206000 4.16e-01
The role of Nef in HIV-1 replication and disease pathogenesis 23 2.60e-01 -0.136000 4.16e-01
RUNX3 regulates NOTCH signaling 12 2.62e-01 -0.187000 4.19e-01
Synthesis of active ubiquitin: roles of E1 and E2 enzymes 30 2.63e-01 -0.118000 4.20e-01
Pre-NOTCH Expression and Processing 46 2.63e-01 -0.095400 4.20e-01
FGFR2 alternative splicing 25 2.63e-01 -0.129000 4.20e-01
Nonhomologous End-Joining (NHEJ) 34 2.64e-01 0.111000 4.20e-01
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 11 2.64e-01 0.195000 4.20e-01
SUMOylation 162 2.65e-01 -0.050900 4.21e-01
VEGFR2 mediated cell proliferation 17 2.66e-01 -0.156000 4.23e-01
Transcription of the HIV genome 67 2.67e-01 -0.078500 4.24e-01
FRS-mediated FGFR3 signaling 12 2.69e-01 -0.184000 4.27e-01
Prostacyclin signalling through prostacyclin receptor 10 2.70e-01 0.201000 4.27e-01
RAB GEFs exchange GTP for GDP on RABs 82 2.71e-01 -0.070500 4.27e-01
Apoptotic execution phase 39 2.71e-01 -0.102000 4.27e-01
NR1H2 and NR1H3-mediated signaling 40 2.74e-01 -0.099900 4.33e-01
Nuclear Pore Complex (NPC) Disassembly 35 2.75e-01 0.107000 4.33e-01
RNA polymerase II transcribes snRNA genes 71 2.76e-01 -0.074800 4.35e-01
VLDLR internalisation and degradation 12 2.77e-01 -0.181000 4.35e-01
Inositol phosphate metabolism 37 2.78e-01 -0.103000 4.37e-01
PRC2 methylates histones and DNA 14 2.79e-01 0.167000 4.38e-01
Cristae formation 13 2.79e-01 -0.173000 4.38e-01
Pre-NOTCH Processing in Golgi 16 2.81e-01 -0.156000 4.39e-01
Downstream signaling of activated FGFR2 17 2.81e-01 -0.151000 4.39e-01
Dissolution of Fibrin Clot 12 2.81e-01 0.180000 4.39e-01
Signaling by cytosolic FGFR1 fusion mutants 17 2.85e-01 -0.150000 4.45e-01
NRIF signals cell death from the nucleus 15 2.87e-01 -0.159000 4.47e-01
Adherens junctions interactions 20 2.87e-01 0.137000 4.47e-01
Syndecan interactions 17 2.88e-01 -0.149000 4.47e-01
Signaling by KIT in disease 19 2.88e-01 -0.141000 4.47e-01
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants 19 2.88e-01 -0.141000 4.47e-01
Signaling by FGFR1 in disease 30 2.89e-01 -0.112000 4.48e-01
Aquaporin-mediated transport 28 2.94e-01 0.115000 4.55e-01
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 38 2.96e-01 0.098100 4.57e-01
Neurotransmitter release cycle 31 2.97e-01 -0.108000 4.58e-01
Other semaphorin interactions 10 2.98e-01 -0.190000 4.60e-01
Ion homeostasis 35 3.00e-01 -0.101000 4.62e-01
TP53 Regulates Transcription of DNA Repair Genes 61 3.01e-01 -0.076600 4.63e-01
NOD1/2 Signaling Pathway 31 3.02e-01 -0.107000 4.63e-01
Sialic acid metabolism 22 3.03e-01 -0.127000 4.66e-01
Mitochondrial translation elongation 87 3.05e-01 -0.063700 4.68e-01
TNF signaling 43 3.06e-01 -0.090300 4.68e-01
SUMO E3 ligases SUMOylate target proteins 156 3.07e-01 -0.047500 4.70e-01
NCAM1 interactions 18 3.08e-01 0.139000 4.70e-01
Signaling by Hippo 18 3.08e-01 -0.139000 4.70e-01
MET activates RAP1 and RAC1 10 3.08e-01 -0.186000 4.70e-01
Mitochondrial protein import 61 3.10e-01 -0.075300 4.72e-01
Formation of the Early Elongation Complex 33 3.10e-01 -0.102000 4.72e-01
Formation of the HIV-1 Early Elongation Complex 33 3.10e-01 -0.102000 4.72e-01
GABA receptor activation 29 3.12e-01 0.109000 4.73e-01
TRAF3-dependent IRF activation pathway 13 3.15e-01 -0.161000 4.78e-01
Role of phospholipids in phagocytosis 17 3.17e-01 -0.140000 4.81e-01
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 13 3.18e-01 0.160000 4.82e-01
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71 3.19e-01 -0.068500 4.82e-01
tRNA modification in the nucleus and cytosol 41 3.19e-01 0.089900 4.82e-01
Signaling by Retinoic Acid 33 3.20e-01 0.100000 4.83e-01
Interleukin-10 signaling 18 3.22e-01 0.135000 4.85e-01
eNOS activation 10 3.22e-01 0.181000 4.85e-01
ADP signalling through P2Y purinoceptor 1 13 3.24e-01 0.158000 4.87e-01
Trafficking of GluR2-containing AMPA receptors 10 3.25e-01 -0.180000 4.88e-01
Vasopressin regulates renal water homeostasis via Aquaporins 24 3.25e-01 0.116000 4.88e-01
Signaling by Leptin 10 3.26e-01 0.179000 4.88e-01
Negative epigenetic regulation of rRNA expression 47 3.27e-01 -0.082700 4.89e-01
Synaptic adhesion-like molecules 14 3.27e-01 0.151000 4.89e-01
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 35 3.28e-01 -0.095600 4.89e-01
Collagen formation 53 3.28e-01 0.077700 4.89e-01
Metabolism of cofactors 18 3.30e-01 0.133000 4.92e-01
RAS processing 17 3.37e-01 -0.135000 5.01e-01
Deadenylation-dependent mRNA decay 55 3.40e-01 -0.074400 5.06e-01
Mitotic G2-G2/M phases 177 3.41e-01 0.041600 5.06e-01
RA biosynthesis pathway 15 3.41e-01 0.142000 5.07e-01
Translesion Synthesis by POLH 18 3.45e-01 0.129000 5.11e-01
Purine catabolism 14 3.49e-01 0.145000 5.16e-01
Synthesis of IP2, IP, and Ins in the cytosol 12 3.50e-01 0.156000 5.18e-01
NoRC negatively regulates rRNA expression 44 3.54e-01 -0.080900 5.21e-01
G beta:gamma signalling through CDC42 11 3.54e-01 0.161000 5.21e-01
Signaling by BRAF and RAF1 fusions 55 3.54e-01 -0.072300 5.21e-01
Formation of Senescence-Associated Heterochromatin Foci (SAHF) 11 3.54e-01 -0.161000 5.21e-01
Interleukin-7 signaling 16 3.54e-01 0.134000 5.21e-01
Downstream signaling of activated FGFR1 20 3.55e-01 -0.119000 5.21e-01
mRNA Splicing - Minor Pathway 52 3.55e-01 -0.074200 5.21e-01
Cdc20:Phospho-APC/C mediated degradation of Cyclin A 69 3.57e-01 -0.064200 5.23e-01
Sensory processing of sound 43 3.58e-01 -0.081000 5.25e-01
SHC-mediated cascade:FGFR2 10 3.59e-01 -0.167000 5.26e-01
Signaling by FGFR in disease 49 3.62e-01 -0.075400 5.29e-01
Growth hormone receptor signaling 20 3.67e-01 0.116000 5.37e-01
DNA Damage Recognition in GG-NER 38 3.69e-01 -0.084300 5.37e-01
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 19 3.69e-01 -0.119000 5.37e-01
Protein ubiquitination 64 3.69e-01 -0.064900 5.37e-01
Synthesis of PIPs at the Golgi membrane 15 3.70e-01 -0.134000 5.38e-01
Interleukin-4 and Interleukin-13 signaling 66 3.74e-01 -0.063400 5.43e-01
Translocation of SLC2A4 (GLUT4) to the plasma membrane 50 3.75e-01 -0.072600 5.44e-01
Signaling by RAF1 mutants 34 3.82e-01 -0.086700 5.53e-01
Assembly and cell surface presentation of NMDA receptors 17 3.82e-01 0.122000 5.53e-01
FGFR1 mutant receptor activation 23 3.83e-01 -0.105000 5.54e-01
MET activates PTK2 signaling 16 3.85e-01 -0.125000 5.56e-01
Sema3A PAK dependent Axon repulsion 14 3.86e-01 -0.134000 5.57e-01
Molecules associated with elastic fibres 19 3.88e-01 0.114000 5.57e-01
Norepinephrine Neurotransmitter Release Cycle 11 3.89e-01 -0.150000 5.57e-01
NOTCH2 Activation and Transmission of Signal to the Nucleus 18 3.89e-01 -0.117000 5.57e-01
Regulation of TP53 Degradation 34 3.90e-01 -0.085300 5.57e-01
Regulation of TP53 Expression and Degradation 34 3.90e-01 -0.085300 5.57e-01
Intrinsic Pathway for Apoptosis 50 3.90e-01 -0.070400 5.57e-01
Termination of O-glycan biosynthesis 10 3.90e-01 -0.157000 5.57e-01
SUMOylation of DNA methylation proteins 16 3.90e-01 0.124000 5.57e-01
NOTCH3 Intracellular Domain Regulates Transcription 17 3.91e-01 -0.120000 5.57e-01
Cell-cell junction organization 42 3.91e-01 0.076600 5.57e-01
Mucopolysaccharidoses 11 3.91e-01 -0.149000 5.57e-01
Pyruvate metabolism and Citric Acid (TCA) cycle 47 3.93e-01 0.072100 5.60e-01
Xenobiotics 15 3.94e-01 0.127000 5.61e-01
Heme degradation 14 3.98e-01 0.130000 5.67e-01
Regulation of APC/C activators between G1/S and early anaphase 77 3.99e-01 -0.055700 5.67e-01
Signaling by SCF-KIT 37 4.01e-01 -0.079800 5.69e-01
TP53 Regulates Transcription of Death Receptors and Ligands 11 4.02e-01 -0.146000 5.70e-01
Regulation of RUNX1 Expression and Activity 17 4.04e-01 -0.117000 5.72e-01
Downregulation of ERBB2 signaling 21 4.07e-01 -0.105000 5.76e-01
G2/M Transition 175 4.09e-01 0.036300 5.78e-01
Metabolism of fat-soluble vitamins 39 4.09e-01 0.076400 5.78e-01
Transcriptional Regulation by MECP2 45 4.10e-01 -0.071100 5.78e-01
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 17 4.10e-01 -0.115000 5.78e-01
HCMV Infection 82 4.11e-01 -0.052600 5.78e-01
Synthesis of PIPs at the late endosome membrane 10 4.13e-01 -0.149000 5.81e-01
Endosomal Sorting Complex Required For Transport (ESCRT) 31 4.16e-01 -0.084400 5.85e-01
NS1 Mediated Effects on Host Pathways 39 4.17e-01 -0.075200 5.85e-01
Metabolism of steroid hormones 23 4.17e-01 0.097800 5.85e-01
Regulation of PTEN mRNA translation 12 4.17e-01 -0.135000 5.85e-01
Pyroptosis 20 4.18e-01 0.105000 5.85e-01
Telomere Extension By Telomerase 22 4.20e-01 0.099200 5.88e-01
Early Phase of HIV Life Cycle 12 4.29e-01 0.132000 5.98e-01
CRMPs in Sema3A signaling 12 4.31e-01 -0.131000 6.02e-01
Activation of kainate receptors upon glutamate binding 16 4.33e-01 0.113000 6.03e-01
Anti-inflammatory response favouring Leishmania parasite infection 63 4.35e-01 -0.057000 6.05e-01
Leishmania parasite growth and survival 63 4.35e-01 -0.057000 6.05e-01
Signaling by NTRK3 (TRKC) 14 4.36e-01 -0.120000 6.05e-01
Nuclear Envelope Breakdown 51 4.36e-01 0.063100 6.05e-01
Synthesis of very long-chain fatty acyl-CoAs 18 4.37e-01 0.106000 6.07e-01
Zinc transporters 15 4.39e-01 -0.115000 6.08e-01
DNA Damage/Telomere Stress Induced Senescence 28 4.39e-01 0.084500 6.08e-01
Sealing of the nuclear envelope (NE) by ESCRT-III 25 4.40e-01 0.089300 6.08e-01
mRNA decay by 3’ to 5’ exoribonuclease 16 4.40e-01 0.111000 6.08e-01
Transcription of E2F targets under negative control by DREAM complex 19 4.44e-01 0.102000 6.11e-01
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 70 4.44e-01 -0.053000 6.11e-01
Sensory processing of sound by inner hair cells of the cochlea 39 4.44e-01 -0.070900 6.11e-01
Signaling by FGFR2 in disease 30 4.46e-01 -0.080400 6.13e-01
Metabolism of non-coding RNA 52 4.46e-01 0.061100 6.13e-01
snRNP Assembly 52 4.46e-01 0.061100 6.13e-01
Nuclear signaling by ERBB4 21 4.49e-01 -0.095600 6.15e-01
Bile acid and bile salt metabolism 38 4.50e-01 -0.070900 6.16e-01
PKA activation 12 4.51e-01 0.126000 6.17e-01
Plasma lipoprotein assembly, remodeling, and clearance 64 4.51e-01 -0.054500 6.17e-01
Signaling by NTRK2 (TRKB) 20 4.54e-01 -0.096700 6.20e-01
TP53 Regulates Transcription of Cell Death Genes 41 4.54e-01 -0.067500 6.20e-01
Pregnenolone biosynthesis 10 4.57e-01 0.136000 6.23e-01
Mitochondrial translation initiation 87 4.58e-01 -0.046100 6.24e-01
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol 22 4.59e-01 -0.091300 6.24e-01
Oxidative Stress Induced Senescence 63 4.59e-01 -0.053900 6.24e-01
GRB2:SOS provides linkage to MAPK signaling for Integrins 13 4.60e-01 0.118000 6.25e-01
Listeria monocytogenes entry into host cells 18 4.63e-01 -0.099900 6.28e-01
Negative regulation of NMDA receptor-mediated neuronal transmission 15 4.64e-01 0.109000 6.28e-01
Purine salvage 11 4.67e-01 0.127000 6.31e-01
Inactivation, recovery and regulation of the phototransduction cascade 20 4.67e-01 -0.094000 6.31e-01
Mitotic Telophase/Cytokinesis 13 4.69e-01 0.116000 6.34e-01
Mitotic G1 phase and G1/S transition 144 4.70e-01 0.034900 6.35e-01
ECM proteoglycans 32 4.73e-01 0.073400 6.38e-01
Regulation of lipid metabolism by PPARalpha 115 4.78e-01 -0.038400 6.44e-01
Muscle contraction 106 4.79e-01 -0.039800 6.45e-01
YAP1- and WWTR1 (TAZ)-stimulated gene expression 12 4.82e-01 -0.117000 6.48e-01
Long-term potentiation 12 4.83e-01 0.117000 6.48e-01
Nucleotide Excision Repair 110 4.83e-01 0.038700 6.48e-01
PI-3K cascade:FGFR2 10 4.84e-01 -0.128000 6.48e-01
Translesion synthesis by POLI 17 4.87e-01 0.097400 6.52e-01
PIWI-interacting RNA (piRNA) biogenesis 18 4.87e-01 -0.094600 6.52e-01
Triglyceride biosynthesis 10 4.87e-01 0.127000 6.52e-01
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 32 4.91e-01 -0.070400 6.55e-01
Regulation of KIT signaling 15 4.91e-01 -0.103000 6.55e-01
Establishment of Sister Chromatid Cohesion 11 4.92e-01 0.120000 6.55e-01
COPI-independent Golgi-to-ER retrograde traffic 31 4.92e-01 -0.071300 6.55e-01
Activation of GABAB receptors 23 4.93e-01 0.082700 6.55e-01
GABA B receptor activation 23 4.93e-01 0.082700 6.55e-01
SUMOylation of DNA damage response and repair proteins 76 4.95e-01 0.045300 6.56e-01
G-protein mediated events 37 4.95e-01 -0.064800 6.56e-01
Neuronal System 207 4.96e-01 0.027500 6.56e-01
Degradation of the extracellular matrix 61 4.96e-01 -0.050400 6.56e-01
PKA activation in glucagon signalling 11 4.96e-01 0.119000 6.56e-01
Metabolism of porphyrins 25 4.97e-01 0.078500 6.56e-01
Generic Transcription Pathway 1024 4.97e-01 0.012700 6.56e-01
PKA-mediated phosphorylation of CREB 14 4.98e-01 0.105000 6.57e-01
Inwardly rectifying K+ channels 17 5.01e-01 0.094300 6.60e-01
EPHA-mediated growth cone collapse 15 5.03e-01 -0.099900 6.61e-01
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 12 5.03e-01 0.112000 6.61e-01
PPARA activates gene expression 113 5.03e-01 -0.036500 6.61e-01
G alpha (12/13) signalling events 59 5.05e-01 -0.050200 6.63e-01
ISG15 antiviral mechanism 72 5.09e-01 -0.045100 6.67e-01
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer’s disease models 20 5.10e-01 -0.085200 6.67e-01
Neurodegenerative Diseases 20 5.10e-01 -0.085200 6.67e-01
Diseases of metabolism 179 5.10e-01 0.028600 6.67e-01
Platelet sensitization by LDL 15 5.12e-01 -0.097900 6.69e-01
Glycogen storage diseases 13 5.13e-01 0.105000 6.69e-01
Keratan sulfate biosynthesis 20 5.14e-01 -0.084200 6.71e-01
Condensation of Prophase Chromosomes 14 5.20e-01 0.099400 6.77e-01
G-protein activation 11 5.21e-01 0.112000 6.78e-01
IRAK2 mediated activation of TAK1 complex 10 5.21e-01 -0.117000 6.78e-01
Senescence-Associated Secretory Phenotype (SASP) 49 5.26e-01 0.052400 6.83e-01
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 18 5.26e-01 0.086300 6.83e-01
KSRP (KHSRP) binds and destabilizes mRNA 17 5.27e-01 -0.088600 6.84e-01
CaM pathway 24 5.30e-01 0.074000 6.86e-01
Calmodulin induced events 24 5.30e-01 0.074000 6.86e-01
RNA Polymerase I Transcription Initiation 44 5.31e-01 -0.054700 6.86e-01
Glutamate Neurotransmitter Release Cycle 17 5.32e-01 -0.087500 6.88e-01
HCMV Early Events 58 5.36e-01 -0.047100 6.90e-01
Integrin signaling 21 5.36e-01 -0.078000 6.90e-01
RHO GTPases Activate NADPH Oxidases 16 5.36e-01 -0.089400 6.90e-01
Meiotic synapsis 26 5.36e-01 0.070100 6.90e-01
Pentose phosphate pathway 13 5.37e-01 0.098900 6.90e-01
Stimuli-sensing channels 59 5.38e-01 -0.046400 6.91e-01
STING mediated induction of host immune responses 10 5.38e-01 -0.112000 6.91e-01
Activation of G protein gated Potassium channels 14 5.42e-01 0.094200 6.93e-01
G protein gated Potassium channels 14 5.42e-01 0.094200 6.93e-01
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 14 5.42e-01 0.094200 6.93e-01
G alpha (s) signalling events 50 5.43e-01 -0.049700 6.94e-01
Signaling by BMP 16 5.43e-01 0.087800 6.94e-01
Maturation of nucleoprotein 11 5.45e-01 0.105000 6.95e-01
APC/C:Cdc20 mediated degradation of mitotic proteins 72 5.46e-01 -0.041200 6.96e-01
Postmitotic nuclear pore complex (NPC) reformation 27 5.47e-01 -0.067000 6.96e-01
BMAL1:CLOCK,NPAS2 activates circadian gene expression 25 5.48e-01 -0.069500 6.97e-01
Synthesis of PC 24 5.48e-01 -0.070900 6.97e-01
Interleukin-6 family signaling 19 5.50e-01 -0.079300 6.98e-01
Glutamate and glutamine metabolism 11 5.50e-01 0.104000 6.98e-01
RND3 GTPase cycle 36 5.51e-01 -0.057500 6.98e-01
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 30 5.52e-01 0.062700 6.99e-01
Regulation of Glucokinase by Glucokinase Regulatory Protein 30 5.52e-01 0.062700 6.99e-01
Hyaluronan uptake and degradation 10 5.55e-01 -0.108000 7.02e-01
TRAF6-mediated induction of TAK1 complex within TLR4 complex 14 5.56e-01 -0.091000 7.02e-01
Prefoldin mediated transfer of substrate to CCT/TriC 25 5.58e-01 -0.067700 7.04e-01
Mitochondrial calcium ion transport 21 5.59e-01 -0.073600 7.05e-01
Regulation of FZD by ubiquitination 15 5.59e-01 -0.087100 7.05e-01
Defective Intrinsic Pathway for Apoptosis 23 5.60e-01 -0.070200 7.05e-01
Signaling by CSF3 (G-CSF) 27 5.63e-01 -0.064400 7.08e-01
Diseases associated with O-glycosylation of proteins 36 5.66e-01 0.055200 7.11e-01
Regulation of IFNG signaling 13 5.67e-01 0.091800 7.11e-01
Signaling by Activin 12 5.70e-01 -0.094800 7.14e-01
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion 13 5.70e-01 -0.091000 7.14e-01
RHO GTPase Effectors 222 5.72e-01 0.022100 7.16e-01
RHO GTPases activate IQGAPs 11 5.74e-01 -0.097800 7.18e-01
Josephin domain DUBs 10 5.75e-01 -0.102000 7.18e-01
Interleukin-37 signaling 15 5.75e-01 -0.083700 7.18e-01
Interleukin-6 signaling 10 5.76e-01 -0.102000 7.18e-01
Activation of the AP-1 family of transcription factors 10 5.78e-01 -0.102000 7.19e-01
Class B/2 (Secretin family receptors) 39 5.78e-01 0.051600 7.19e-01
Platelet Aggregation (Plug Formation) 24 5.78e-01 -0.065600 7.19e-01
FRS-mediated FGFR2 signaling 12 5.80e-01 -0.092200 7.21e-01
SUMOylation of chromatin organization proteins 55 5.86e-01 0.042400 7.28e-01
RNA Polymerase III Transcription Initiation From Type 3 Promoter 28 5.87e-01 -0.059300 7.28e-01
Non-integrin membrane-ECM interactions 37 5.88e-01 -0.051500 7.28e-01
Translesion synthesis by POLK 17 5.90e-01 0.075500 7.31e-01
Rap1 signalling 11 5.91e-01 -0.093600 7.31e-01
SLBP independent Processing of Histone Pre-mRNAs 10 5.94e-01 0.097500 7.34e-01
RHO GTPases activate PKNs 31 5.94e-01 -0.055300 7.34e-01
Interleukin-2 family signaling 29 5.97e-01 -0.056800 7.36e-01
Regulation of beta-cell development 27 5.97e-01 0.058800 7.36e-01
DNA Damage Bypass 47 6.00e-01 0.044300 7.39e-01
TP53 Regulates Transcription of Cell Cycle Genes 47 6.03e-01 0.043900 7.41e-01
Phase 0 - rapid depolarisation 17 6.04e-01 0.072600 7.43e-01
Branched-chain amino acid catabolism 21 6.05e-01 0.065200 7.43e-01
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 26 6.07e-01 -0.058300 7.45e-01
Respiratory electron transport 103 6.08e-01 -0.029300 7.45e-01
Sema4D induced cell migration and growth-cone collapse 20 6.09e-01 -0.066000 7.45e-01
SUMOylation of RNA binding proteins 46 6.09e-01 0.043600 7.45e-01
Metabolism of lipids 592 6.09e-01 0.012400 7.45e-01
Glycogen synthesis 14 6.12e-01 -0.078300 7.48e-01
VxPx cargo-targeting to cilium 18 6.12e-01 -0.069000 7.48e-01
Post-translational protein phosphorylation 91 6.14e-01 -0.030600 7.49e-01
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20 6.15e-01 -0.064900 7.49e-01
Formation of apoptosome 11 6.16e-01 -0.087400 7.49e-01
Regulation of the apoptosome activity 11 6.16e-01 -0.087400 7.49e-01
Competing endogenous RNAs (ceRNAs) regulate PTEN translation 11 6.18e-01 -0.086900 7.51e-01
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects 16 6.21e-01 0.071400 7.53e-01
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) 16 6.21e-01 0.071400 7.53e-01
Signaling by NOTCH2 24 6.26e-01 -0.057500 7.56e-01
Metal ion SLC transporters 23 6.26e-01 -0.058700 7.56e-01
Signaling by ALK 20 6.26e-01 -0.062900 7.56e-01
RIPK1-mediated regulated necrosis 27 6.26e-01 -0.054100 7.56e-01
Regulation of necroptotic cell death 27 6.26e-01 -0.054100 7.56e-01
RUNX2 regulates osteoblast differentiation 16 6.27e-01 0.070300 7.56e-01
Gamma carboxylation, hypusine formation and arylsulfatase activation 37 6.27e-01 0.046100 7.56e-01
Triglyceride catabolism 12 6.28e-01 -0.080700 7.56e-01
Potassium Channels 37 6.28e-01 0.046000 7.56e-01
Alpha-protein kinase 1 signaling pathway 11 6.29e-01 0.084000 7.56e-01
Cytochrome c-mediated apoptotic response 13 6.29e-01 -0.077300 7.56e-01
Metabolism of carbohydrates 235 6.32e-01 0.018200 7.59e-01
Peptide ligand-binding receptors 51 6.35e-01 0.038500 7.61e-01
Laminin interactions 21 6.36e-01 0.059600 7.62e-01
DCC mediated attractive signaling 12 6.38e-01 -0.078500 7.63e-01
Formation of the cornified envelope 21 6.38e-01 -0.059300 7.63e-01
Nef mediated downregulation of MHC class I complex cell surface expression 10 6.41e-01 0.085100 7.66e-01
Prolactin receptor signaling 11 6.42e-01 -0.081000 7.66e-01
Class I peroxisomal membrane protein import 19 6.42e-01 0.061600 7.66e-01
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 73 6.44e-01 -0.031300 7.68e-01
Activation of SMO 14 6.46e-01 -0.071000 7.69e-01
Nuclear import of Rev protein 33 6.46e-01 -0.046200 7.69e-01
Unblocking of NMDA receptors, glutamate binding and activation 11 6.48e-01 0.079500 7.71e-01
E3 ubiquitin ligases ubiquitinate target proteins 44 6.52e-01 -0.039400 7.73e-01
Regulation of FOXO transcriptional activity by acetylation 10 6.52e-01 -0.082400 7.73e-01
Cohesin Loading onto Chromatin 10 6.52e-01 -0.082400 7.73e-01
Interaction between L1 and Ankyrins 15 6.53e-01 -0.067000 7.74e-01
Signaling by NODAL 15 6.54e-01 0.066900 7.74e-01
Pyruvate metabolism 24 6.55e-01 0.052600 7.74e-01
RNA Pol II CTD phosphorylation and interaction with CE 27 6.55e-01 -0.049600 7.74e-01
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 27 6.55e-01 -0.049600 7.74e-01
The phototransduction cascade 21 6.56e-01 -0.056100 7.74e-01
Activation of Matrix Metalloproteinases 15 6.57e-01 0.066100 7.75e-01
Glycogen breakdown (glycogenolysis) 15 6.58e-01 0.066100 7.75e-01
Citric acid cycle (TCA cycle) 21 6.59e-01 0.055700 7.75e-01
Inhibition of DNA recombination at telomere 21 6.62e-01 0.055100 7.78e-01
Cytosolic iron-sulfur cluster assembly 11 6.62e-01 0.076100 7.78e-01
tRNA processing in the nucleus 54 6.66e-01 -0.033900 7.82e-01
Neurotransmitter receptors and postsynaptic signal transmission 108 6.69e-01 0.023800 7.84e-01
PLC beta mediated events 33 6.70e-01 -0.042900 7.84e-01
Caspase activation via extrinsic apoptotic signalling pathway 21 6.70e-01 -0.053800 7.84e-01
Fertilization 10 6.71e-01 -0.077700 7.85e-01
Notch-HLH transcription pathway 24 6.71e-01 -0.050000 7.85e-01
Interferon gamma signaling 57 6.79e-01 0.031700 7.93e-01
Chemokine receptors bind chemokines 13 6.83e-01 -0.065500 7.96e-01
Recognition of DNA damage by PCNA-containing replication complex 30 6.83e-01 0.043100 7.96e-01
Ca2+ pathway 44 6.86e-01 0.035300 7.99e-01
Synthesis of Leukotrienes (LT) and Eoxins (EX) 10 6.87e-01 -0.073700 7.99e-01
Signal amplification 19 6.87e-01 -0.053300 8.00e-01
Purine ribonucleoside monophosphate biosynthesis 11 6.90e-01 0.069400 8.02e-01
Amyloid fiber formation 41 6.91e-01 0.035900 8.02e-01
Dopamine Neurotransmitter Release Cycle 14 6.96e-01 0.060400 8.06e-01
G beta:gamma signalling through PLC beta 11 6.96e-01 0.068000 8.06e-01
Presynaptic function of Kainate receptors 11 6.96e-01 0.068000 8.06e-01
Initiation of Nuclear Envelope (NE) Reformation 19 6.98e-01 -0.051500 8.07e-01
NCAM signaling for neurite out-growth 35 7.02e-01 0.037400 8.11e-01
G alpha (z) signalling events 25 7.08e-01 -0.043300 8.18e-01
DNA Double Strand Break Response 40 7.09e-01 -0.034100 8.18e-01
Translesion synthesis by REV1 16 7.12e-01 0.053300 8.21e-01
Ca-dependent events 25 7.14e-01 0.042400 8.22e-01
The NLRP3 inflammasome 14 7.14e-01 0.056600 8.22e-01
G-protein beta:gamma signalling 17 7.18e-01 -0.050500 8.26e-01
RNA Polymerase I Transcription Termination 27 7.26e-01 -0.039000 8.34e-01
G alpha (i) signalling events 121 7.26e-01 -0.018500 8.34e-01
Transcription-Coupled Nucleotide Excision Repair (TC-NER) 78 7.28e-01 -0.022800 8.34e-01
mRNA decay by 5’ to 3’ exoribonuclease 15 7.28e-01 -0.051900 8.34e-01
RNA Polymerase I Promoter Clearance 48 7.32e-01 -0.028600 8.37e-01
RNA Polymerase I Transcription 48 7.32e-01 -0.028600 8.37e-01
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 13 7.32e-01 -0.054800 8.37e-01
Transcriptional Regulation by E2F6 34 7.33e-01 0.033900 8.37e-01
SUMOylation of ubiquitinylation proteins 38 7.35e-01 -0.031800 8.38e-01
Interactions of Rev with host cellular proteins 36 7.35e-01 -0.032600 8.38e-01
Metalloprotease DUBs 16 7.35e-01 0.048800 8.38e-01
Gene Silencing by RNA 68 7.36e-01 -0.023700 8.38e-01
Tryptophan catabolism 10 7.43e-01 0.059900 8.45e-01
Downregulation of ERBB2:ERBB3 signaling 10 7.46e-01 -0.059100 8.47e-01
TNFR1-induced NFkappaB signaling pathway 25 7.46e-01 -0.037400 8.47e-01
Processing of SMDT1 15 7.47e-01 -0.048200 8.47e-01
Sensory perception of sweet, bitter, and umami (glutamate) taste 11 7.49e-01 0.055800 8.49e-01
Negative regulators of DDX58/IFIH1 signaling 35 7.50e-01 -0.031200 8.50e-01
Protein folding 78 7.53e-01 0.020600 8.52e-01
O-linked glycosylation 64 7.53e-01 0.022700 8.52e-01
Gluconeogenesis 27 7.54e-01 0.034800 8.53e-01
Response to elevated platelet cytosolic Ca2+ 106 7.57e-01 0.017400 8.55e-01
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 27 7.58e-01 -0.034200 8.55e-01
IL-6-type cytokine receptor ligand interactions 13 7.58e-01 -0.049300 8.55e-01
Cargo trafficking to the periciliary membrane 47 7.61e-01 0.025700 8.56e-01
Aflatoxin activation and detoxification 15 7.61e-01 0.045400 8.56e-01
ADORA2B mediated anti-inflammatory cytokines production 42 7.61e-01 0.027100 8.56e-01
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 24 7.62e-01 -0.035800 8.56e-01
G1/S Transition 127 7.65e-01 0.015400 8.59e-01
Regulation of localization of FOXO transcription factors 10 7.66e-01 -0.054200 8.59e-01
Diseases of glycosylation 99 7.67e-01 0.017300 8.59e-01
Detoxification of Reactive Oxygen Species 28 7.67e-01 -0.032300 8.59e-01
Glucuronidation 10 7.68e-01 -0.054000 8.59e-01
Platelet homeostasis 48 7.69e-01 -0.024500 8.60e-01
Transport of Ribonucleoproteins into the Host Nucleus 31 7.69e-01 -0.030400 8.60e-01
Caspase-mediated cleavage of cytoskeletal proteins 11 7.71e-01 0.050800 8.61e-01
Glycosaminoglycan metabolism 90 7.71e-01 -0.017700 8.61e-01
Gene expression (Transcription) 1265 7.76e-01 -0.004840 8.65e-01
Complex I biogenesis 57 7.76e-01 0.021800 8.65e-01
TICAM1,TRAF6-dependent induction of TAK1 complex 10 7.77e-01 -0.051700 8.65e-01
The citric acid (TCA) cycle and respiratory electron transport 151 7.81e-01 0.013200 8.67e-01
Blood group systems biosynthesis 13 7.81e-01 0.044600 8.67e-01
TNFR1-induced proapoptotic signaling 12 7.82e-01 0.046200 8.67e-01
Regulation of MECP2 expression and activity 29 7.82e-01 -0.029700 8.67e-01
Regulation of pyruvate dehydrogenase (PDH) complex 15 7.88e-01 0.040000 8.74e-01
Surfactant metabolism 14 7.89e-01 0.041200 8.74e-01
G beta:gamma signalling through PI3Kgamma 13 7.92e-01 0.042400 8.76e-01
Depolymerisation of the Nuclear Lamina 14 7.93e-01 -0.040600 8.77e-01
Transport of Mature mRNAs Derived from Intronless Transcripts 42 7.94e-01 -0.023300 8.77e-01
Nuclear Envelope (NE) Reassembly 69 7.96e-01 0.018000 8.78e-01
Regulation of innate immune responses to cytosolic DNA 11 7.98e-01 -0.044700 8.78e-01
Interferon Signaling 147 7.98e-01 0.012300 8.78e-01
DAG and IP3 signaling 30 7.98e-01 0.027000 8.78e-01
RMTs methylate histone arginines 30 7.98e-01 0.027000 8.78e-01
Transport of the SLBP Dependant Mature mRNA 35 7.99e-01 -0.024900 8.78e-01
Inactivation of CSF3 (G-CSF) signaling 22 7.99e-01 0.031300 8.79e-01
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression 17 8.03e-01 -0.034900 8.81e-01
Signaling by PDGF 44 8.04e-01 0.021700 8.81e-01
Adrenaline,noradrenaline inhibits insulin secretion 15 8.04e-01 -0.037100 8.81e-01
Interactions of Vpr with host cellular proteins 36 8.04e-01 -0.023900 8.81e-01
Metabolism of nitric oxide: NOS3 activation and regulation 13 8.07e-01 -0.039200 8.82e-01
Lewis blood group biosynthesis 11 8.07e-01 -0.042600 8.82e-01
SLC transporter disorders 70 8.08e-01 -0.016800 8.83e-01
mRNA Capping 29 8.15e-01 -0.025200 8.90e-01
Recycling of bile acids and salts 13 8.16e-01 -0.037300 8.90e-01
Glycogen metabolism 25 8.20e-01 -0.026200 8.94e-01
NOTCH4 Intracellular Domain Regulates Transcription 15 8.23e-01 -0.033300 8.97e-01
Protein localization 150 8.28e-01 -0.010300 9.01e-01
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 108 8.29e-01 -0.012000 9.01e-01
Apoptotic factor-mediated response 18 8.30e-01 0.029200 9.01e-01
Ras activation upon Ca2+ influx through NMDA receptor 16 8.30e-01 -0.030900 9.01e-01
Pre-NOTCH Transcription and Translation 31 8.31e-01 -0.022200 9.01e-01
Activation of NMDA receptors and postsynaptic events 56 8.31e-01 0.016500 9.01e-01
Switching of origins to a post-replicative state 87 8.32e-01 -0.013200 9.01e-01
Regulation of TP53 Activity 152 8.32e-01 -0.009970 9.01e-01
Vpr-mediated nuclear import of PICs 33 8.34e-01 0.021100 9.01e-01
RNA Polymerase I Promoter Escape 29 8.34e-01 -0.022500 9.01e-01
PECAM1 interactions 11 8.37e-01 0.035800 9.04e-01
Tight junction interactions 21 8.38e-01 0.025800 9.04e-01
Formation of tubulin folding intermediates by CCT/TriC 20 8.39e-01 -0.026200 9.05e-01
ADP signalling through P2Y purinoceptor 12 12 8.41e-01 0.033400 9.06e-01
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 39 8.42e-01 -0.018400 9.07e-01
Golgi Cisternae Pericentriolar Stack Reorganization 14 8.46e-01 -0.029900 9.10e-01
FCGR3A-mediated IL10 synthesis 23 8.50e-01 0.022800 9.13e-01
Factors involved in megakaryocyte development and platelet production 103 8.53e-01 0.010600 9.16e-01
Platelet degranulation 103 8.53e-01 0.010600 9.16e-01
Nucleotide catabolism 28 8.58e-01 0.019500 9.20e-01
Processing of Capped Intronless Pre-mRNA 28 8.59e-01 -0.019400 9.20e-01
MASTL Facilitates Mitotic Progression 10 8.59e-01 -0.032500 9.20e-01
p130Cas linkage to MAPK signaling for integrins 13 8.64e-01 0.027500 9.24e-01
TNFs bind their physiological receptors 11 8.72e-01 -0.028100 9.32e-01
Chylomicron assembly 10 8.73e-01 0.029200 9.32e-01
Regulated Necrosis 47 8.73e-01 0.013400 9.32e-01
Inflammasomes 18 8.79e-01 -0.020700 9.38e-01
Processing and activation of SUMO 10 8.80e-01 0.027500 9.38e-01
DNA Replication Pre-Initiation 85 8.82e-01 -0.009310 9.39e-01
Protein methylation 15 8.83e-01 0.021900 9.40e-01
BBSome-mediated cargo-targeting to cilium 23 8.85e-01 0.017400 9.40e-01
Diseases associated with glycosylation precursor biosynthesis 18 8.86e-01 -0.019600 9.40e-01
Thrombin signalling through proteinase activated receptors (PARs) 21 8.86e-01 -0.018100 9.40e-01
APC/C-mediated degradation of cell cycle proteins 84 8.88e-01 -0.008930 9.41e-01
Regulation of mitotic cell cycle 84 8.88e-01 -0.008930 9.41e-01
O-linked glycosylation of mucins 34 8.88e-01 0.013900 9.41e-01
Smooth Muscle Contraction 28 8.90e-01 -0.015100 9.42e-01
Caspase activation via Death Receptors in the presence of ligand 13 8.93e-01 0.021500 9.44e-01
Transmission across Chemical Synapses 146 8.94e-01 -0.006410 9.44e-01
Interleukin-15 signaling 12 8.95e-01 0.022000 9.44e-01
Killing mechanisms 10 8.96e-01 -0.023900 9.44e-01
WNT5:FZD7-mediated leishmania damping 10 8.96e-01 -0.023900 9.44e-01
HuR (ELAVL1) binds and stabilizes mRNA 10 8.96e-01 -0.023800 9.44e-01
Cellular Senescence 124 8.99e-01 0.006580 9.47e-01
Thromboxane signalling through TP receptor 14 9.00e-01 -0.019400 9.47e-01
Interconversion of nucleotide di- and triphosphates 27 9.05e-01 0.013300 9.51e-01
HCMV Late Events 55 9.06e-01 -0.009220 9.52e-01
RUNX2 regulates bone development 22 9.07e-01 0.014400 9.52e-01
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 13 9.08e-01 -0.018500 9.52e-01
Triglyceride metabolism 22 9.12e-01 0.013700 9.55e-01
Signaling by FGFR2 IIIa TM 17 9.16e-01 0.014800 9.59e-01
Heme biosynthesis 13 9.17e-01 0.016700 9.60e-01
Viral Messenger RNA Synthesis 43 9.18e-01 -0.009050 9.60e-01
Gap junction trafficking and regulation 14 9.21e-01 -0.015300 9.60e-01
CASP8 activity is inhibited 10 9.21e-01 -0.018100 9.60e-01
Dimerization of procaspase-8 10 9.21e-01 -0.018100 9.60e-01
Regulation by c-FLIP 10 9.21e-01 -0.018100 9.60e-01
Cellular hexose transport 16 9.26e-01 -0.013500 9.63e-01
NEP/NS2 Interacts with the Cellular Export Machinery 31 9.28e-01 -0.009340 9.63e-01
Cyclin D associated events in G1 46 9.30e-01 0.007530 9.63e-01
G1 Phase 46 9.30e-01 0.007530 9.63e-01
Regulation of TP53 Activity through Association with Co-factors 11 9.33e-01 -0.014700 9.63e-01
TRP channels 10 9.33e-01 0.015300 9.63e-01
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 21 9.34e-01 0.010500 9.63e-01
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 12 9.34e-01 0.013900 9.63e-01
Dual incision in TC-NER 65 9.34e-01 -0.005910 9.63e-01
HIV Transcription Initiation 45 9.35e-01 -0.007060 9.63e-01
RNA Polymerase II HIV Promoter Escape 45 9.35e-01 -0.007060 9.63e-01
RNA Polymerase II Promoter Escape 45 9.35e-01 -0.007060 9.63e-01
RNA Polymerase II Transcription Initiation 45 9.35e-01 -0.007060 9.63e-01
RNA Polymerase II Transcription Initiation And Promoter Clearance 45 9.35e-01 -0.007060 9.63e-01
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 45 9.35e-01 -0.007060 9.63e-01
Post NMDA receptor activation events 47 9.36e-01 -0.006790 9.63e-01
Gap-filling DNA repair synthesis and ligation in TC-NER 64 9.36e-01 0.005810 9.63e-01
Glucose metabolism 81 9.38e-01 0.004980 9.65e-01
Plasma lipoprotein assembly 17 9.42e-01 0.010300 9.68e-01
RHO GTPases activate CIT 19 9.45e-01 0.009130 9.70e-01
Metabolism of folate and pterines 16 9.46e-01 -0.009830 9.70e-01
SUMOylation of SUMOylation proteins 34 9.46e-01 0.006730 9.70e-01
Transcriptional regulation by small RNAs 47 9.49e-01 0.005380 9.72e-01
Assembly of the ORC complex at the origin of replication 10 9.50e-01 0.011600 9.72e-01
Voltage gated Potassium channels 12 9.53e-01 0.009910 9.74e-01
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 11 9.53e-01 0.010300 9.74e-01
Defects in vitamin and cofactor metabolism 20 9.54e-01 -0.007500 9.74e-01
Interleukin-27 signaling 10 9.54e-01 -0.010500 9.74e-01
Sensory processing of sound by outer hair cells of the cochlea 31 9.55e-01 0.005820 9.74e-01
Glycerophospholipid biosynthesis 90 9.58e-01 0.003240 9.76e-01
Regulation of insulin secretion 47 9.58e-01 -0.004430 9.76e-01
Serotonin Neurotransmitter Release Cycle 10 9.59e-01 0.009340 9.76e-01
Collagen degradation 20 9.64e-01 -0.005900 9.80e-01
Integration of energy metabolism 73 9.65e-01 0.002940 9.80e-01
Glutamate binding, activation of AMPA receptors and synaptic plasticity 21 9.66e-01 0.005430 9.80e-01
Trafficking of AMPA receptors 21 9.66e-01 0.005430 9.80e-01
Mitotic Prophase 81 9.71e-01 -0.002370 9.84e-01
SUMOylation of transcription factors 16 9.72e-01 0.005010 9.85e-01
Synthesis of PE 12 9.73e-01 0.005700 9.85e-01
Gap junction trafficking 12 9.74e-01 -0.005450 9.85e-01
Transport of Mature mRNA Derived from an Intronless Transcript 41 9.75e-01 -0.002860 9.85e-01
Oncogene Induced Senescence 33 9.79e-01 0.002600 9.89e-01
Transcriptional regulation of pluripotent stem cells 21 9.81e-01 0.003010 9.90e-01
RNA Polymerase II Transcription 1142 9.84e-01 -0.000350 9.93e-01
Processing of Intronless Pre-mRNAs 19 9.85e-01 -0.002490 9.93e-01
Chondroitin sulfate/dermatan sulfate metabolism 40 9.86e-01 0.001610 9.93e-01
Export of Viral Ribonucleoproteins from Nucleus 32 9.87e-01 -0.001660 9.94e-01
Diseases of carbohydrate metabolism 29 9.88e-01 -0.001650 9.94e-01
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 99 9.90e-01 0.000729 9.95e-01
Chaperonin-mediated protein folding 72 9.91e-01 0.000811 9.95e-01
Interleukin-35 Signalling 10 9.91e-01 -0.001970 9.95e-01
Other interleukin signaling 18 9.92e-01 0.001290 9.95e-01
FGFR2 mutant receptor activation 20 9.95e-01 -0.000820 9.97e-01
Rev-mediated nuclear export of HIV RNA 34 9.95e-01 0.000584 9.97e-01
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 24 9.97e-01 0.000465 9.98e-01
Transport of the SLBP independent Mature mRNA 34 9.98e-01 -0.000288 9.98e-01



Detailed Gene set reports



Cellular responses to stimuli

Cellular responses to stimuli
155
set Cellular responses to stimuli
setSize 641
pANOVA 1.36e-21
s.dist -0.222
p.adjustANOVA 1.87e-18



Top enriched genes

Top 20 genes
GeneID Gene Rank
HSPA5 -7144
CALR -7142
DNAJB11 -7141
HYOU1 -7140
HERPUD1 -7137
DNAJC3 -7131
HSP90B1 -7129
DNAJB9 -7125
SYVN1 -7108
PDIA6 -7106
EDEM1 -7103
WFS1 -7096
ATP6V0B -7064
CSRP1 -7054
GFPT1 -7051
DDIT3 -7047
EIF2AK3 -7028
HM13 -7025
FLCN -7022
RRAGC -7009

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
HSPA5 -7144
CALR -7142
DNAJB11 -7141
HYOU1 -7140
HERPUD1 -7137
DNAJC3 -7131
HSP90B1 -7129
DNAJB9 -7125
SYVN1 -7108
PDIA6 -7106
EDEM1 -7103
WFS1 -7096
ATP6V0B -7064
CSRP1 -7054
GFPT1 -7051
DDIT3 -7047
EIF2AK3 -7028
HM13 -7025
FLCN -7022
RRAGC -7009
MAFK -6985
RPL36AL -6981
MYDGF -6976
SERP1 -6964
ATF6 -6949
KDM6B -6944
WIPI1 -6942
ATP6V1D -6922
RPS19BP1 -6915
SHC1 -6910
ATP6V0D1 -6908
SSR1 -6907
FKBP14 -6896
SRPRB -6893
P4HB -6884
ERN1 -6872
CREB3L2 -6832
ATF5 -6830
SEC13 -6812
TXNRD1 -6806
TRIB3 -6798
HSPA13 -6786
TSPYL2 -6784
PPP1R15A -6783
FNIP1 -6782
EGLN2 -6763
MT1G -6753
NCOA6 -6745
RRAGD -6743
PPARA -6722
VCP -6720
HDGF -6715
MT1F -6694
PRDX1 -6673
PSMF1 -6663
CRTC2 -6651
SCO2 -6638
ATP6V0E1 -6622
SESN2 -6610
HSPA9 -6580
COX20 -6555
HSPH1 -6524
EXOSC6 -6503
VHL -6491
DNAJC7 -6489
KEAP1 -6482
EP300 -6470
TATDN2 -6467
MAPKAPK2 -6461
PSME4 -6450
PSMD2 -6435
GPX2 -6408
TPP1 -6407
POM121 -6353
DNAJB1 -6326
ATP6V1E1 -6271
ATF2 -6175
TLN1 -6146
ATP6V0C -6086
HIRA -6076
POM121C -6045
CXXC1 -6033
ERF -6016
MEF2D -5995
AKT1S1 -5990
CEBPG -5987
ADD1 -5966
MBTPS1 -5958
PSMD6 -5951
ABCC1 -5950
ATP6V1C2 -5929
SIN3A -5884
RORA -5875
PPARGC1A -5869
UBN1 -5851
FKBP4 -5807
AGO3 -5803
PSMA2 -5801
MAP4K4 -5792
MAPKAPK3 -5773
SEC31A -5766
LRPPRC -5756
PSMA1 -5730
ATF4 -5664
PRKCD -5638
EZH2 -5631
SIRT1 -5628
ATP6V1B2 -5574
PSMC1 -5564
SLC38A9 -5539
PSMD3 -5535
HSPB8 -5506
GRB10 -5504
FNIP2 -5498
CA9 -5494
PSME2 -5481
MED1 -5451
AQP8 -5439
NCF2 -5438
SP1 -5412
NPAS2 -5410
HSPA14 -5393
ATP6V1G1 -5352
PSMD1 -5351
BAG3 -5335
LAMTOR5 -5293
TERF1 -5276
NUP205 -5275
RPL19 -5254
BAG5 -5238
HMGA1 -5226
EIF2S1 -5190
FOS -5174
ACTR1A -5162
DNAJB6 -5140
RPS7 -5138
PPP2R5B -5131
DCP2 -5125
GSK3B -5101
UBA52 -5068
MAPK1 -5066
CDK4 -5064
CSNK2A1 -5040
COX5A -5033
RPL11 -5032
RPL10 -5026
RPS15 -5010
RPA1 -5008
NUP188 -4991
FAU -4990
DEPDC5 -4989
RPL14 -4978
BACH1 -4970
CRTC3 -4964
ATP6V1C1 -4946
ANAPC15 -4945
MT1E -4931
EPAS1 -4915
PSMB6 -4888
PSMC6 -4878
CDKN2D -4869
CAPZA1 -4855
RRAGB -4819
PSMC4 -4808
TNRC6C -4805
SRPRA -4802
DNAJC2 -4791
RPS5 -4778
NUP88 -4777
EXOSC5 -4766
HMOX2 -4742
NUP50 -4733
RPS11 -4702
NCOA1 -4665
RPS19 -4661
HSPA8 -4654
RPS28 -4652
PSMD9 -4638
CHD9 -4634
GCN1 -4627
NR1D1 -4622
CREBRF -4582
PARN -4578
CSNK2A2 -4546
BAG1 -4540
COX8A -4517
MAP2K4 -4505
SEH1L -4472
CTDSP2 -4462
EIF2S2 -4458
VEGFA -4456
HSP90AB1 -4426
ATP6V1H -4423
NCOR2 -4409
MAP2K7 -4399
RPLP1 -4391
MAPK7 -4382
NCOR1 -4374
PSMB7 -4372
CBX8 -4370
RPS12 -4367
COX7A2L -4360
FBXL17 -4348
ST13 -4320
EGLN1 -4303
RPL27A -4297
RPLP0 -4290
TERF2IP -4282
PHC1 -4280
UBB -4263
MT1X -4230
TNRC6B -4212
PSMA4 -4211
BMI1 -4180
HIF1A -4165
RPL35A -4159
EEF1A1 -4138
CUL1 -4129
PSMC5 -4091
RPL30 -4081
RAD50 -4078
RXRA -4073
CBX4 -4063
MAPKAPK5 -4050
COX4I1 -4038
RPS9 -4028
NR3C1 -4005
COX14 -4004
UBE2D3 -3997
RPL18 -3961
DCTN2 -3957
MTF1 -3947
SERPINH1 -3945
IGFBP1 -3931
DYNC1LI2 -3897
CREBBP -3888
RPL26L1 -3873
COX7B -3866
RPS6KA1 -3857
RPS29 -3844
RPL6 -3843
PSME3 -3813
KLHDC3 -3802
ATP6V1A -3777
NUP98 -3764
RHEB -3762
EP400 -3754
LMNA -3717
RBX1 -3714
GSK3A -3684
MTOR -3683
DEDD2 -3679
EIF2S3 -3669
CREB3 -3650
DCTN5 -3634
DYNC1H1 -3614
TXN -3611
CDKN1A -3580
STIP1 -3571
RPL28 -3546
GSR -3534
RPSA -3520
NFKB1 -3507
RPL8 -3467
RPS4X -3464
RPS2 -3462
EXOSC3 -3453
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
HSPA6 -3353
RPS24 -3352
MAP2K3 -3342
SH3BP4 -3331
RBBP4 -3297
CCAR2 -3268
RPS14 -3261
DNAJA2 -3258
ZBTB17 -3194
RPS27L -3180
COX6B1 -3158
RPS10 -3155
SEM1 -3130
COX6A1 -3107
PSMA3 -3078
CUL3 -3056
RPS6KA3 -3030
HBA1 -3024
RPS15A -3019
SCO1 -3018
ELOB -3004
RPL7 -2984
RPL34 -2974
APOB -2964
JUN -2934
PSMD8 -2928
RPS21 -2927
EIF2AK1 -2921
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
DYNC1I2 -2780
RPS27A -2773
PSMA5 -2715
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RELA -2632
LAMTOR3 -2631
RPS13 -2581
TFDP1 -2579
PSMD13 -2577
RPL4 -2563
MDM4 -2561
DYNC1LI1 -2519
NFYA -2482
RPS23 -2467
RPL37A -2451
HSF1 -2414
PSMC2 -2389
MAP2K6 -2351
PSME1 -2348
DNAJA1 -2311
RPL39 -2270
RPL18A -2240
RPL7A -2233
ETS2 -2186
TNFRSF21 -2173
CABIN1 -2162
RPS4Y1 -2120
NFE2L2 -2108
RPL27 -2070
CCNE2 -2024
TP53 -2020
RAI1 -2008
DCTN4 -1937
NUP214 -1926
PSMB3 -1915
RPL23 -1913
UBE2S -1872
XPO1 -1864
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
EHMT1 -1678
CLOCK -1648
ANAPC2 -1639
DCTN1 -1635
TBL1X -1621
ARFGAP1 -1587
DIS3 -1573
CAPZA2 -1549
ANAPC11 -1544
CDC27 -1529
PSMC3 -1509
NDC1 -1490
EIF2AK4 -1455
BLVRA -1440
LY96 -1339
RPL15 -1313
PRDX5 -1274
CAPZB -1169
RPL3 -1165
RPS6KA2 -1149
PSMB4 -1144
CEBPB -1129
MT2A -1121
RPL17 -1119
RPS8 -1071
HSP90AA1 -1030
KHSRP -994
RPL12 -983
PRDX2 -961
MDM2 -956
RPS25 -937
UBE2D2 -913
COX16 -910
PSMA7 -892
MRPL18 -882
ATP6V1F -868
SLC46A1 -835
CDKN1B -786
LAMTOR1 -774
PSMB5 -742
RPL13 -706
MAPK8 -700
NFYC -690
SKP1 -544
ATP6V1E2 -534
RPL5 -495
PSMD11 -432
NDUFA4 -390
ARNTL -359
NUP160 -329
DCTN6 -318
MT1A -309
NUP62 -299
TXN2 -243
RPL22L1 -214
ERO1A -198
CDC26 -197
RPS3A -179
RPS27 -152
LAMTOR2 -148
PSMA6 -126
PRDX6 -54
RANBP2 -4
HDAC3 38
YWHAE 129
PRDX3 165
TCIRG1 180
YIF1A 195
FZR1 201
MAPK11 251
RPL9 261
NUDT2 301
ANAPC4 305
TXNRD2 308
SURF1 327
RPL31 330
COX6C 344
SUZ12 346
CUL2 359
EHMT2 400
RPTOR 407
RPS26 419
PSMB10 423
E2F3 444
RB1 470
EXOSC8 472
CREB1 474
CYCS 562
TPR 565
NRIP1 570
PDIA5 579
BMT2 638
ELOC 645
ATP6V1G2 690
COX5B 704
MT-CO2 716
HIGD1A 720
GPX8 743
ATP6V0D2 747
UBC 779
BLVRB 811
PHC3 843
HSPA4 925
CRYAB 939
KDELR3 976
ARNT 1014
SULT1A3 1040
PSMB1 1054
CDC16 1175
GOSR2 1238
BAG2 1269
NUP133 1362
HSBP1 1372
RPL21 1385
TBL1XR1 1404
PREB 1446
DCTN3 1457
COX7C 1483
ATM 1503
NR3C2 1520
COX11 1523
KAT5 1580
CDKN2B 1710
CAMK2D 1711
MAPK9 1760
TNRC6A 1824
LAMTOR4 1834
HSPA1A 1835
MLST8 1875
PSMB2 1876
ANAPC1 1998
EPO 2073
ATP7A 2111
RPL22 2142
ITFG2 2143
CAMK2G 2145
TGS1 2148
CYBA 2202
MINK1 2261
MAPK14 2269
SMARCD3 2305
EED 2369
NUP58 2380
RNF2 2454
ATF3 2488
DYNLL1 2509
EGLN3 2588
RRAGA 2609
NUP153 2712
GPX7 2739
CCNE1 2754
NUP43 2808
RPL36A 2875
CBX6 2911
MIOS 2912
MAPK10 2952
AAAS 2965
CRTC1 2969
LIMD1 2987
ACD 3041
ALB 3096
GPX1 3161
EXOSC4 3220
EXOSC9 3293
PTK6 3304
NUP54 3310
EXTL2 3353
HSPA2 3418
EXOSC1 3486
CARM1 3517
UBE2D1 3523
ETS1 3554
EXTL3 3575
CXCL8 3625
ATOX1 3659
MBTPS2 3687
CDKN2A 3704
PHC2 3713
UBE2E1 3733
PTGES3 3734
EXOSC2 3779
COX18 3788
ASF1A 3905
HSPA4L 3936
ANAPC5 3942
BAG4 4019
SIN3B 4029
RING1 4067
MRE11 4100
CDK2 4114
COX19 4126
ACADVL 4157
NPRL3 4164
WTIP 4170
NUP85 4178
CITED2 4227
CDKN2C 4232
STAT3 4253
IGFBP7 4272
HIF1AN 4302
PSMD12 4303
AGO1 4307
TINF2 4357
CUL7 4377
RAE1 4394
CSNK2B 4415
IMPACT 4432
HIF3A 4444
WDR24 4466
KPTN 4478
TERF2 4479
ID1 4484
NBN 4533
ATP6V1B1 4549
CAMK2A 4566
PSMD4 4567
HMOX1 4592
STAP2 4664
PLA2G4B 4716
CDK6 4754
NCOA2 4780
HELZ2 4786
NUP155 4796
TFDP2 4856
CCS 4860
TNIK 4872
NPRL2 4876
WDR59 4915
PSMD10 4933
PSMD7 4942
SESN1 4963
CAT 5018
SZT2 5052
NFYB 5091
FABP1 5092
PSMD5 5116
RBBP7 5134
EXOSC7 5196
FKBP5 5342
H2AFX 5356
GPX3 5394
ATR 5478
HSPA12A 5480
PSMB9 5491
TACO1 5527
ACTR10 5570
COL4A6 5592
HMGA2 5643
ATP6V0E2 5683
SOD1 5779
NUP93 5831
CREB3L4 5920
XBP1 5937
SKP2 5946
HDAC6 5953
PSMD14 5974
NUP35 5982
CREB3L3 5999
AJUBA 6013
DYNLL2 6044
ANAPC10 6071
NUP107 6076
CDC23 6113
POT1 6132
HIKESHI 6144
ASNS 6208
ANAPC7 6249
DDX11 6254
ANAPC16 6307
RPA3 6375
MOV10 6408
E2F2 6426
MT-CO1 6493
AGO4 6581
CCNA2 6594
MAPK3 6640
SCMH1 6656
NUP210 6802
CHAC1 6845
EXTL1 6941
CBX2 6958
RPA2 6961
APOA1 6993
E2F1 7096
NUP37 7100
LMNB1 7101
UBE2C 7137
MT-CO3 7316
SOD2 7342
TXNIP 7384



Cellular responses to stress

Cellular responses to stress
156
set Cellular responses to stress
setSize 633
pANOVA 2.2e-20
s.dist -0.217
p.adjustANOVA 1.51e-17



Top enriched genes

Top 20 genes
GeneID Gene Rank
HSPA5 -7144
CALR -7142
DNAJB11 -7141
HYOU1 -7140
HERPUD1 -7137
DNAJC3 -7131
HSP90B1 -7129
DNAJB9 -7125
SYVN1 -7108
PDIA6 -7106
EDEM1 -7103
WFS1 -7096
ATP6V0B -7064
GFPT1 -7051
DDIT3 -7047
EIF2AK3 -7028
HM13 -7025
FLCN -7022
RRAGC -7009
MAFK -6985

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
HSPA5 -7144
CALR -7142
DNAJB11 -7141
HYOU1 -7140
HERPUD1 -7137
DNAJC3 -7131
HSP90B1 -7129
DNAJB9 -7125
SYVN1 -7108
PDIA6 -7106
EDEM1 -7103
WFS1 -7096
ATP6V0B -7064
GFPT1 -7051
DDIT3 -7047
EIF2AK3 -7028
HM13 -7025
FLCN -7022
RRAGC -7009
MAFK -6985
RPL36AL -6981
MYDGF -6976
SERP1 -6964
ATF6 -6949
KDM6B -6944
WIPI1 -6942
ATP6V1D -6922
RPS19BP1 -6915
SHC1 -6910
ATP6V0D1 -6908
SSR1 -6907
FKBP14 -6896
SRPRB -6893
P4HB -6884
ERN1 -6872
CREB3L2 -6832
ATF5 -6830
SEC13 -6812
TXNRD1 -6806
TRIB3 -6798
HSPA13 -6786
TSPYL2 -6784
PPP1R15A -6783
FNIP1 -6782
EGLN2 -6763
NCOA6 -6745
RRAGD -6743
PPARA -6722
VCP -6720
HDGF -6715
PRDX1 -6673
PSMF1 -6663
CRTC2 -6651
SCO2 -6638
ATP6V0E1 -6622
SESN2 -6610
HSPA9 -6580
COX20 -6555
HSPH1 -6524
EXOSC6 -6503
VHL -6491
DNAJC7 -6489
KEAP1 -6482
EP300 -6470
TATDN2 -6467
MAPKAPK2 -6461
PSME4 -6450
PSMD2 -6435
GPX2 -6408
TPP1 -6407
POM121 -6353
DNAJB1 -6326
ATP6V1E1 -6271
ATF2 -6175
TLN1 -6146
ATP6V0C -6086
HIRA -6076
POM121C -6045
CXXC1 -6033
ERF -6016
MEF2D -5995
AKT1S1 -5990
CEBPG -5987
ADD1 -5966
MBTPS1 -5958
PSMD6 -5951
ABCC1 -5950
ATP6V1C2 -5929
SIN3A -5884
RORA -5875
PPARGC1A -5869
UBN1 -5851
FKBP4 -5807
AGO3 -5803
PSMA2 -5801
MAP4K4 -5792
MAPKAPK3 -5773
SEC31A -5766
LRPPRC -5756
PSMA1 -5730
ATF4 -5664
PRKCD -5638
EZH2 -5631
SIRT1 -5628
ATP6V1B2 -5574
PSMC1 -5564
SLC38A9 -5539
PSMD3 -5535
HSPB8 -5506
GRB10 -5504
FNIP2 -5498
CA9 -5494
PSME2 -5481
MED1 -5451
AQP8 -5439
NCF2 -5438
SP1 -5412
NPAS2 -5410
HSPA14 -5393
ATP6V1G1 -5352
PSMD1 -5351
BAG3 -5335
LAMTOR5 -5293
TERF1 -5276
NUP205 -5275
RPL19 -5254
BAG5 -5238
HMGA1 -5226
EIF2S1 -5190
FOS -5174
ACTR1A -5162
DNAJB6 -5140
RPS7 -5138
PPP2R5B -5131
DCP2 -5125
GSK3B -5101
UBA52 -5068
MAPK1 -5066
CDK4 -5064
CSNK2A1 -5040
COX5A -5033
RPL11 -5032
RPL10 -5026
RPS15 -5010
RPA1 -5008
NUP188 -4991
FAU -4990
DEPDC5 -4989
RPL14 -4978
BACH1 -4970
CRTC3 -4964
ATP6V1C1 -4946
ANAPC15 -4945
EPAS1 -4915
PSMB6 -4888
PSMC6 -4878
CDKN2D -4869
CAPZA1 -4855
RRAGB -4819
PSMC4 -4808
TNRC6C -4805
SRPRA -4802
DNAJC2 -4791
RPS5 -4778
NUP88 -4777
EXOSC5 -4766
HMOX2 -4742
NUP50 -4733
RPS11 -4702
NCOA1 -4665
RPS19 -4661
HSPA8 -4654
RPS28 -4652
PSMD9 -4638
CHD9 -4634
GCN1 -4627
NR1D1 -4622
CREBRF -4582
PARN -4578
CSNK2A2 -4546
BAG1 -4540
COX8A -4517
MAP2K4 -4505
SEH1L -4472
CTDSP2 -4462
EIF2S2 -4458
VEGFA -4456
HSP90AB1 -4426
ATP6V1H -4423
NCOR2 -4409
MAP2K7 -4399
RPLP1 -4391
MAPK7 -4382
NCOR1 -4374
PSMB7 -4372
CBX8 -4370
RPS12 -4367
COX7A2L -4360
FBXL17 -4348
ST13 -4320
EGLN1 -4303
RPL27A -4297
RPLP0 -4290
TERF2IP -4282
PHC1 -4280
UBB -4263
TNRC6B -4212
PSMA4 -4211
BMI1 -4180
HIF1A -4165
RPL35A -4159
EEF1A1 -4138
CUL1 -4129
PSMC5 -4091
RPL30 -4081
RAD50 -4078
RXRA -4073
CBX4 -4063
MAPKAPK5 -4050
COX4I1 -4038
RPS9 -4028
NR3C1 -4005
COX14 -4004
UBE2D3 -3997
RPL18 -3961
DCTN2 -3957
SERPINH1 -3945
IGFBP1 -3931
DYNC1LI2 -3897
CREBBP -3888
RPL26L1 -3873
COX7B -3866
RPS6KA1 -3857
RPS29 -3844
RPL6 -3843
PSME3 -3813
KLHDC3 -3802
ATP6V1A -3777
NUP98 -3764
RHEB -3762
EP400 -3754
LMNA -3717
RBX1 -3714
GSK3A -3684
MTOR -3683
DEDD2 -3679
EIF2S3 -3669
CREB3 -3650
DCTN5 -3634
DYNC1H1 -3614
TXN -3611
CDKN1A -3580
STIP1 -3571
RPL28 -3546
GSR -3534
RPSA -3520
NFKB1 -3507
RPL8 -3467
RPS4X -3464
RPS2 -3462
EXOSC3 -3453
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
HSPA6 -3353
RPS24 -3352
MAP2K3 -3342
SH3BP4 -3331
RBBP4 -3297
CCAR2 -3268
RPS14 -3261
DNAJA2 -3258
ZBTB17 -3194
RPS27L -3180
COX6B1 -3158
RPS10 -3155
SEM1 -3130
COX6A1 -3107
PSMA3 -3078
CUL3 -3056
RPS6KA3 -3030
HBA1 -3024
RPS15A -3019
SCO1 -3018
ELOB -3004
RPL7 -2984
RPL34 -2974
APOB -2964
JUN -2934
PSMD8 -2928
RPS21 -2927
EIF2AK1 -2921
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
DYNC1I2 -2780
RPS27A -2773
PSMA5 -2715
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RELA -2632
LAMTOR3 -2631
RPS13 -2581
TFDP1 -2579
PSMD13 -2577
RPL4 -2563
MDM4 -2561
DYNC1LI1 -2519
NFYA -2482
RPS23 -2467
RPL37A -2451
HSF1 -2414
PSMC2 -2389
MAP2K6 -2351
PSME1 -2348
DNAJA1 -2311
RPL39 -2270
RPL18A -2240
RPL7A -2233
ETS2 -2186
TNFRSF21 -2173
CABIN1 -2162
RPS4Y1 -2120
NFE2L2 -2108
RPL27 -2070
CCNE2 -2024
TP53 -2020
RAI1 -2008
DCTN4 -1937
NUP214 -1926
PSMB3 -1915
RPL23 -1913
UBE2S -1872
XPO1 -1864
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
EHMT1 -1678
CLOCK -1648
ANAPC2 -1639
DCTN1 -1635
TBL1X -1621
ARFGAP1 -1587
DIS3 -1573
CAPZA2 -1549
ANAPC11 -1544
CDC27 -1529
PSMC3 -1509
NDC1 -1490
EIF2AK4 -1455
BLVRA -1440
LY96 -1339
RPL15 -1313
PRDX5 -1274
CAPZB -1169
RPL3 -1165
RPS6KA2 -1149
PSMB4 -1144
CEBPB -1129
RPL17 -1119
RPS8 -1071
HSP90AA1 -1030
KHSRP -994
RPL12 -983
PRDX2 -961
MDM2 -956
RPS25 -937
UBE2D2 -913
COX16 -910
PSMA7 -892
MRPL18 -882
ATP6V1F -868
SLC46A1 -835
CDKN1B -786
LAMTOR1 -774
PSMB5 -742
RPL13 -706
MAPK8 -700
NFYC -690
SKP1 -544
ATP6V1E2 -534
RPL5 -495
PSMD11 -432
NDUFA4 -390
ARNTL -359
NUP160 -329
DCTN6 -318
NUP62 -299
TXN2 -243
RPL22L1 -214
ERO1A -198
CDC26 -197
RPS3A -179
RPS27 -152
LAMTOR2 -148
PSMA6 -126
PRDX6 -54
RANBP2 -4
HDAC3 38
YWHAE 129
PRDX3 165
TCIRG1 180
YIF1A 195
FZR1 201
MAPK11 251
RPL9 261
NUDT2 301
ANAPC4 305
TXNRD2 308
SURF1 327
RPL31 330
COX6C 344
SUZ12 346
CUL2 359
EHMT2 400
RPTOR 407
RPS26 419
PSMB10 423
E2F3 444
RB1 470
EXOSC8 472
CREB1 474
CYCS 562
TPR 565
NRIP1 570
PDIA5 579
BMT2 638
ELOC 645
ATP6V1G2 690
COX5B 704
MT-CO2 716
HIGD1A 720
GPX8 743
ATP6V0D2 747
UBC 779
BLVRB 811
PHC3 843
HSPA4 925
CRYAB 939
KDELR3 976
ARNT 1014
SULT1A3 1040
PSMB1 1054
CDC16 1175
GOSR2 1238
BAG2 1269
NUP133 1362
HSBP1 1372
RPL21 1385
TBL1XR1 1404
PREB 1446
DCTN3 1457
COX7C 1483
ATM 1503
NR3C2 1520
COX11 1523
KAT5 1580
CDKN2B 1710
CAMK2D 1711
MAPK9 1760
TNRC6A 1824
LAMTOR4 1834
HSPA1A 1835
MLST8 1875
PSMB2 1876
ANAPC1 1998
EPO 2073
ATP7A 2111
RPL22 2142
ITFG2 2143
CAMK2G 2145
TGS1 2148
CYBA 2202
MINK1 2261
MAPK14 2269
SMARCD3 2305
EED 2369
NUP58 2380
RNF2 2454
ATF3 2488
DYNLL1 2509
EGLN3 2588
RRAGA 2609
NUP153 2712
GPX7 2739
CCNE1 2754
NUP43 2808
RPL36A 2875
CBX6 2911
MIOS 2912
MAPK10 2952
AAAS 2965
CRTC1 2969
LIMD1 2987
ACD 3041
ALB 3096
GPX1 3161
EXOSC4 3220
EXOSC9 3293
PTK6 3304
NUP54 3310
EXTL2 3353
HSPA2 3418
EXOSC1 3486
CARM1 3517
UBE2D1 3523
ETS1 3554
EXTL3 3575
CXCL8 3625
ATOX1 3659
MBTPS2 3687
CDKN2A 3704
PHC2 3713
UBE2E1 3733
PTGES3 3734
EXOSC2 3779
COX18 3788
ASF1A 3905
HSPA4L 3936
ANAPC5 3942
BAG4 4019
SIN3B 4029
RING1 4067
MRE11 4100
CDK2 4114
COX19 4126
ACADVL 4157
NPRL3 4164
WTIP 4170
NUP85 4178
CITED2 4227
CDKN2C 4232
STAT3 4253
IGFBP7 4272
HIF1AN 4302
PSMD12 4303
AGO1 4307
TINF2 4357
CUL7 4377
RAE1 4394
CSNK2B 4415
IMPACT 4432
HIF3A 4444
WDR24 4466
KPTN 4478
TERF2 4479
ID1 4484
NBN 4533
ATP6V1B1 4549
CAMK2A 4566
PSMD4 4567
HMOX1 4592
STAP2 4664
PLA2G4B 4716
CDK6 4754
NCOA2 4780
HELZ2 4786
NUP155 4796
TFDP2 4856
CCS 4860
TNIK 4872
NPRL2 4876
WDR59 4915
PSMD10 4933
PSMD7 4942
SESN1 4963
CAT 5018
SZT2 5052
NFYB 5091
FABP1 5092
PSMD5 5116
RBBP7 5134
EXOSC7 5196
FKBP5 5342
H2AFX 5356
GPX3 5394
ATR 5478
HSPA12A 5480
PSMB9 5491
TACO1 5527
ACTR10 5570
COL4A6 5592
HMGA2 5643
ATP6V0E2 5683
SOD1 5779
NUP93 5831
CREB3L4 5920
XBP1 5937
SKP2 5946
HDAC6 5953
PSMD14 5974
NUP35 5982
CREB3L3 5999
AJUBA 6013
DYNLL2 6044
ANAPC10 6071
NUP107 6076
CDC23 6113
POT1 6132
HIKESHI 6144
ASNS 6208
ANAPC7 6249
DDX11 6254
ANAPC16 6307
RPA3 6375
MOV10 6408
E2F2 6426
MT-CO1 6493
AGO4 6581
CCNA2 6594
MAPK3 6640
SCMH1 6656
NUP210 6802
CHAC1 6845
EXTL1 6941
CBX2 6958
RPA2 6961
APOA1 6993
E2F1 7096
NUP37 7100
LMNB1 7101
UBE2C 7137
MT-CO3 7316
SOD2 7342
TXNIP 7384



Infectious disease

Infectious disease
509
set Infectious disease
setSize 637
pANOVA 1.06e-18
s.dist -0.206
p.adjustANOVA 4.88e-16



Top enriched genes

Top 20 genes
GeneID Gene Rank
CALR -7142
DNAJC3 -7131
CANX -7092
ANTXR2 -7077
MAGT1 -7045
MAP1LC3B -7040
RAMP1 -7037
RPN1 -7013
RPL36AL -6981
DVL3 -6967
CTSL -6951
ATP1B3 -6941
TGFB1 -6934
MET -6878
SFPQ -6854
ACTG1 -6841
SEC13 -6812
TXNRD1 -6806
ST3GAL4 -6801
STT3A -6796

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CALR -7142
DNAJC3 -7131
CANX -7092
ANTXR2 -7077
MAGT1 -7045
MAP1LC3B -7040
RAMP1 -7037
RPN1 -7013
RPL36AL -6981
DVL3 -6967
CTSL -6951
ATP1B3 -6941
TGFB1 -6934
MET -6878
SFPQ -6854
ACTG1 -6841
SEC13 -6812
TXNRD1 -6806
ST3GAL4 -6801
STT3A -6796
ATP1A1 -6777
ST6GALNAC4 -6726
VCP -6720
KPNA1 -6701
FURIN -6683
DDX5 -6665
PSMF1 -6663
ATP1B1 -6624
CHMP4C -6557
WASL -6543
VHL -6491
KEAP1 -6482
BRD4 -6479
RAN -6476
PSME4 -6450
CLTA -6439
PSMD2 -6435
DDOST -6429
TCEA1 -6409
P2RY11 -6403
MGAT1 -6401
KPNB1 -6379
IPO5 -6366
POM121 -6353
BRMS1 -6309
NT5E -6296
UVRAG -6290
FNTA -6282
MGAT4B -6279
LCK -6250
DAD1 -6240
CLTC -6220
RPN2 -6193
TAF4 -6108
ARPC4 -6094
ITPR3 -6088
MAP2K2 -6087
ADM2 -6068
POM121C -6045
PTHLH -6042
ARF1 -6021
PSMD6 -5951
PRKCSH -5934
MYO9B -5920
ST3GAL1 -5905
FXYD2 -5865
MGAT5 -5854
HTR7 -5841
ADAM17 -5836
GTF2E2 -5813
RAB7A -5810
FKBP4 -5807
PSMA2 -5801
SUPT5H -5767
GTF2H1 -5744
ELK1 -5733
PSMA1 -5730
WASF1 -5712
CBL -5708
GTF2B -5704
CBLL1 -5694
CHMP1A -5693
CRK -5650
EZH2 -5631
MTA2 -5619
PSMC1 -5564
PSMD3 -5535
EDEM2 -5520
ISG15 -5488
PSME2 -5481
POLR2L -5471
CDK7 -5444
BRK1 -5431
RAB5A -5408
EGFR -5383
PDCD6IP -5380
PSMD1 -5351
CSNK1A1 -5349
ACTR3 -5296
MYO10 -5290
NELFA -5284
POLR2F -5283
TAF13 -5280
NUP205 -5275
RPL19 -5254
SAP30 -5230
HMGA1 -5226
PIK3C3 -5220
FKBP1A -5189
TBK1 -5169
RPS7 -5138
FUT8 -5134
GSK3B -5101
VAMP2 -5088
UBA52 -5068
MAPK1 -5066
ACTB -5057
EEF2 -5049
RPL11 -5032
RPL10 -5026
CHMP4B -5021
MGAT4A -5018
RPS15 -5010
PLK2 -5005
NUP188 -4991
FAU -4990
RPL14 -4978
JAK1 -4963
PAK2 -4957
IL6R -4943
PSMB6 -4888
PSMC6 -4878
ENO1 -4866
TRIM27 -4835
CHD4 -4830
PGK1 -4810
PSMC4 -4808
RPS5 -4778
NUP88 -4777
GRSF1 -4747
NUP50 -4733
MYH9 -4726
RPS11 -4702
VPS37B -4696
CCNT1 -4690
POLR2E -4667
RPS19 -4661
RPS28 -4652
VAV3 -4642
PSMD9 -4638
VPS37C -4620
GNAI3 -4609
AP2M1 -4603
KPNA2 -4575
MBD3 -4543
SSRP1 -4525
GPS2 -4524
ST3GAL2 -4518
GNB2 -4514
MAP2K4 -4505
TAF4B -4483
ABI1 -4478
SEH1L -4472
CTDP1 -4461
VEGFA -4456
PPIA -4443
ARPC1B -4429
HSP90AB1 -4426
ATP6V1H -4423
NCOR2 -4409
HBEGF -4402
RNGTT -4400
MAP2K7 -4399
RPLP1 -4391
NCOR1 -4374
PSMB7 -4372
RPS12 -4367
KPNA3 -4357
PTK2 -4346
ITPR1 -4321
RPL27A -4297
RPLP0 -4290
PRMT1 -4281
UBB -4263
PSMA4 -4211
HGS -4210
AP1S2 -4204
SH3GL1 -4200
VPS37A -4187
XRCC5 -4164
RPL35A -4159
ITGB1 -4145
MAP2K1 -4120
GATAD2A -4108
PSMC5 -4091
RPL30 -4081
RPS9 -4028
GGT5 -4012
NR3C1 -4005
SLC25A5 -4001
RPL18 -3961
GNAI2 -3904
DYNC1LI2 -3897
SAP30L -3887
RPL26L1 -3873
RPS29 -3844
RPL6 -3843
PARP16 -3842
PSME3 -3813
PLCG2 -3766
NELFCD -3765
NUP98 -3764
SLC25A6 -3733
GNAZ -3724
RBX1 -3714
GPHA2 -3711
POLR2B -3699
ATP1B2 -3692
GSK3A -3684
CD9 -3660
MVB12B -3629
DYNC1H1 -3614
TXN -3611
ROCK1 -3594
POLR2H -3593
MAN1B1 -3561
RPL28 -3546
RPSA -3520
NFKB1 -3507
MYO5A -3500
AP2A2 -3499
RCOR1 -3493
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
POLR2C -3425
RPL37 -3413
RPS17 -3369
WASF2 -3366
RPS24 -3352
SAP18 -3349
MAP2K3 -3342
MGAT2 -3327
RBBP4 -3297
RPS14 -3261
GNB1 -3237
SLC25A4 -3203
HMG20B -3184
RPS27L -3180
DPEP1 -3163
RPS10 -3155
SEM1 -3130
GTF2F1 -3103
TRIM28 -3099
RHBDF2 -3089
PSMA3 -3078
CUL3 -3056
GRB2 -3047
LYN -3038
RPS15A -3019
ELOB -3004
RPL7 -2984
RPL34 -2974
WIPF2 -2965
TAF5 -2960
JUN -2934
PSMD8 -2928
RPS21 -2927
AP2S1 -2922
BECN1 -2900
RPS16 -2898
RIPK1 -2886
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
FXYD1 -2847
ELOA -2831
SUPT4H1 -2826
ADCY6 -2818
HNRNPK -2808
NCKAP1 -2788
DYNC1I2 -2780
ELMO1 -2779
RPS27A -2773
ROCK2 -2772
JAK2 -2719
PSMA5 -2715
RPL23A -2692
RPL10A -2689
RPS6 -2681
HDAC1 -2676
RPS18 -2648
RPL41 -2635
RELA -2632
RPS13 -2581
PSMD13 -2577
RPL4 -2563
FNTB -2551
ADM -2543
B2M -2523
DYNC1LI1 -2519
GNAI1 -2495
RPS23 -2467
RPL37A -2451
PSMC2 -2389
STX1A -2377
TLR9 -2371
MAP2K6 -2351
PSME1 -2348
IFNAR2 -2313
NELFB -2298
SUDS3 -2287
MOGS -2275
RPL39 -2270
DVL1 -2264
RPL18A -2240
RPL7A -2233
ARPC2 -2209
CDC42 -2172
RCC1 -2159
NCBP1 -2151
TSG101 -2130
RPS4Y1 -2120
NFE2L2 -2108
NMT1 -2085
RPL27 -2070
PABPN1 -2037
NPM1 -2033
ERCC3 -2013
DBP -2002
CRBN -1928
NUP214 -1926
AP1G1 -1916
PSMB3 -1915
RPL23 -1913
SRPK2 -1905
AP2A1 -1902
UBAP1 -1894
XPO1 -1864
ST6GAL1 -1828
IMPDH1 -1807
RPL24 -1804
RPL38 -1791
RPS20 -1754
DUSP16 -1750
RPL26 -1747
CHMP5 -1722
ATP1A3 -1706
KPNA4 -1701
TBL1X -1621
PARP6 -1567
ARPC5 -1511
PSMC3 -1509
NDC1 -1490
ELL -1439
PRKACB -1429
YES1 -1340
CHD3 -1321
UBE2I -1318
RPL15 -1313
NFKB2 -1311
CUL5 -1229
TAF3 -1222
TUSC3 -1219
MYO1C -1212
SNF8 -1198
ABI2 -1197
RPL3 -1165
PSMB4 -1144
RPL17 -1119
GATAD2B -1092
CCNK -1089
CHMP2A -1088
PHF21A -1078
RPS8 -1071
MAN2A1 -1040
PRKAR1B -1038
HSP90AA1 -1030
TAF7 -1012
GNB3 -1008
RPL12 -983
NCKAP1L -972
RPS25 -937
VPS4B -934
SH3KBP1 -917
DVL2 -905
PSMA7 -892
CHMP2B -878
PRKAR2A -860
GALNT1 -816
PSMB5 -742
AP1S3 -739
RPL13 -706
MAPK8 -700
ADCY2 -667
CALM1 -655
BAIAP2 -637
POLR2J -603
REST -593
ERCC2 -583
PRKX -553
SKP1 -544
RPL5 -495
TAF9 -483
PSMD11 -432
TAF11 -429
GTF2H4 -406
HDAC2 -338
NUP160 -329
NUP62 -299
GGT1 -250
RPL22L1 -214
TAF2 -206
MNAT1 -205
RPS3A -179
ARID4A -156
RPS27 -152
PSMA6 -126
RANBP2 -4
PRKAR1A 4
NOXO1 10
NELFE 26
XRCC6 28
HDAC3 38
RAC1 44
STAT2 76
ENTPD1 184
KPNA5 258
RPL9 261
GTF2A1 328
RPL31 330
SUZ12 346
FEN1 367
ATP1A4 412
PACS1 414
RPS26 419
PSMB10 423
GNAS 459
PARP4 462
RB1 470
CREB1 474
ARID4B 480
TPR 565
TAF10 626
ELOC 645
GNB5 700
SIGMAR1 753
UBC 779
TAF1 788
VPS37D 809
CHMP4A 909
AP1M2 914
AP1B1 940
ELMO2 942
GPR39 994
IFNGR2 997
PML 1051
PSMB1 1054
PIK3R4 1132
TAF6 1145
CHMP3 1229
EPS15 1254
RANBP1 1308
GPR83 1350
NUP133 1362
RPL21 1385
BTRC 1386
TBL1XR1 1404
ACTR2 1435
TMPRSS2 1456
NCK1 1525
CPSF4 1570
IFNGR1 1624
VTA1 1653
SUGT1 1662
MGAT4C 1714
PRKACA 1736
MTA1 1810
HSPA1A 1835
STX1B 1841
PSMB2 1876
NMT2 1894
GNB4 1936
FYN 1937
CYFIP1 1939
POLR2G 2003
ABL1 2023
AP2B1 2029
IL18 2102
RPL22 2142
CYBA 2202
ITPR2 2257
MAPK14 2269
EED 2369
VPS4A 2374
NUP58 2380
POLR2D 2418
MEFV 2468
VPS36 2474
CYSLTR1 2493
DYNLL1 2509
PLCG1 2511
COMT 2597
WASF3 2619
CDK9 2631
CHMP7 2690
POLR2A 2705
NUP153 2712
ACE2 2757
NUP43 2808
GANAB 2813
VAV2 2817
RPL36A 2875
EIF2AK2 2886
VPS25 2895
AP1M1 2926
AAAS 2965
SV2A 2966
PARP1 2974
SRPK1 3007
ARPC1A 3022
STAM2 3080
SUPT16H 3202
PARP8 3263
CTNNB1 3272
SUMO1 3308
NUP54 3310
CORO1A 3359
XRCC4 3376
RANGAP1 3458
VAMP1 3484
IRS1 3502
DOCK1 3540
GIPR 3556
DAXX 3635
PTGES3 3734
BANF1 3790
ARPC3 3797
ENTPD5 3958
SRC 3962
TBP 3968
VPS33B 4043
CCNT2 4117
GNG5 4123
VPS28 4152
IFNAR1 4161
NUP85 4178
KDM1A 4224
ADCY9 4287
PSMD12 4303
GTF2H5 4373
RAE1 4394
GNG7 4426
RNMT 4440
ANTXR1 4532
GTF2F2 4556
PSMD4 4567
HMOX1 4592
POLR2I 4594
DRD5 4609
CBX1 4668
ZCRB1 4731
NUP155 4796
ADCY1 4808
AHCYL1 4874
IMPDH2 4910
PSMD10 4933
PSMD7 4942
TYK2 5066
STAM 5109
PSMD5 5116
TUBB 5125
ADORA2B 5127
RBBP7 5134
GPR176 5289
GTF2H2 5321
ADORA2A 5330
PARP14 5386
P2RX4 5401
GSDMD 5413
GTF2A2 5445
NCKIPSD 5477
FZD7 5487
PSMB9 5491
NOXA1 5500
GTF2E1 5502
CCNH 5556
RNF213 5584
MVB12A 5589
HLA-A 5777
AP1S1 5804
NUP93 5831
PARP10 5859
CHMP6 5904
ST3GAL3 5918
PSTPIP1 5948
POLR2K 5962
PSMD14 5974
NUP35 5982
GTF2H3 6024
DYNLL2 6044
CD4 6074
NUP107 6076
TAF9B 6106
CASP1 6109
GNG4 6164
LIG1 6206
CYFIP2 6224
RAMP2 6288
ADCY7 6316
MTA3 6411
LIG4 6454
IL1R1 6510
TAF12 6601
DUT 6636
MAPK3 6640
GNG10 6779
NUP210 6802
NCBP2 6823
CEBPD 6867
PYCARD 6900
PARP9 6988
TAF15 7061
APOBEC3G 7066
MC1R 7078
NUP37 7100
CTNND1 7129
PSIP1 7193
NEDD4L 7233
CDH1 7296
JAK3 7326
C3 7357
TXNIP 7384



SRP-dependent cotranslational protein targeting to membrane

SRP-dependent cotranslational protein targeting to membrane
1038
set SRP-dependent cotranslational protein targeting to membrane
setSize 109
pANOVA 1.48e-17
s.dist -0.473
p.adjustANOVA 5.09e-15



Top enriched genes

Top 20 genes
GeneID Gene Rank
SEC61A1 -7030
RPN1 -7013
SSR4 -7004
TRAM1 -6997
SEC11C -6991
RPL36AL -6981
SEC61B -6958
SSR3 -6928
SSR1 -6907
SRPRB -6893
SPCS3 -6781
SSR2 -6759
DDOST -6429
SRP68 -6420
SRP19 -6363
RPN2 -6193
SRP14 -5938
SPCS2 -5930
SRP72 -5526
RPL19 -5254

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SEC61A1 -7030
RPN1 -7013
SSR4 -7004
TRAM1 -6997
SEC11C -6991
RPL36AL -6981
SEC61B -6958
SSR3 -6928
SSR1 -6907
SRPRB -6893
SPCS3 -6781
SSR2 -6759
DDOST -6429
SRP68 -6420
SRP19 -6363
RPN2 -6193
SRP14 -5938
SPCS2 -5930
SRP72 -5526
RPL19 -5254
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
SRPRA -4802
RPS5 -4778
RPS11 -4702
RPS19 -4661
RPS28 -4652
RPLP1 -4391
RPS12 -4367
RPL27A -4297
RPLP0 -4290
RPL35A -4159
RPL30 -4081
SEC61G -4052
RPS9 -4028
RPL18 -3961
RPL26L1 -3873
RPS29 -3844
RPL6 -3843
RPL28 -3546
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
SEC11A -3046
RPS15A -3019
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
RPS27A -2773
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RPS13 -2581
RPL4 -2563
RPS23 -2467
RPL37A -2451
RPL39 -2270
RPL18A -2240
RPL7A -2233
RPS4Y1 -2120
RPL27 -2070
SRP54 -1969
RPL23 -1913
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
SEC61A2 -1397
RPL15 -1313
RPL3 -1165
RPL17 -1119
RPS8 -1071
RPL12 -983
RPS25 -937
RPL13 -706
RPL5 -495
RPL22L1 -214
RPS3A -179
RPS27 -152
RPL9 261
RPL31 330
RPS26 419
RPL21 1385
RPL22 2142
SPCS1 2416
RPL36A 2875
SRP9 5604



Asparagine N-linked glycosylation

Asparagine N-linked glycosylation
74
set Asparagine N-linked glycosylation
setSize 252
pANOVA 6.7e-17
s.dist -0.306
p.adjustANOVA 1.85e-14



Top enriched genes

Top 20 genes
GeneID Gene Rank
CALR -7142
SEC24D -7134
SEL1L -7124
SYVN1 -7108
EDEM1 -7103
CANX -7092
PDIA3 -7086
SLC17A5 -7072
TMED2 -7071
MCFD2 -7065
GFPT1 -7051
MIA3 -7049
DERL2 -7046
MAGT1 -7045
RPN1 -7013
FUT3 -7001
OS9 -6986
UGGT1 -6954
TMED7 -6933
NANS -6906

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CALR -7142
SEC24D -7134
SEL1L -7124
SYVN1 -7108
EDEM1 -7103
CANX -7092
PDIA3 -7086
SLC17A5 -7072
TMED2 -7071
MCFD2 -7065
GFPT1 -7051
MIA3 -7049
DERL2 -7046
MAGT1 -7045
RPN1 -7013
FUT3 -7001
OS9 -6986
UGGT1 -6954
TMED7 -6933
NANS -6906
MLEC -6902
GMPPB -6844
SEC24A -6839
SEC13 -6812
ST3GAL4 -6801
STT3A -6796
ANK2 -6778
TMEM115 -6764
NEU1 -6752
ST6GALNAC4 -6726
VCP -6720
SLC35C1 -6667
RNF5 -6629
ALG3 -6601
TRAPPC10 -6585
LMAN2 -6558
ALG2 -6554
COPB2 -6532
CD55 -6517
PPP6R1 -6511
ARCN1 -6505
TMED9 -6502
ALG5 -6471
MAN1A2 -6460
DDOST -6429
DERL1 -6423
MGAT1 -6401
NUS1 -6395
RNF185 -6359
GMPPA -6346
CTSA -6288
MGAT4B -6279
DAD1 -6240
SEC24C -6236
TBC1D20 -6203
RPN2 -6193
RNF103 -6135
TMED10 -6116
ALG12 -6081
DPAGT1 -6046
ARF1 -6021
SEC16A -5971
COPE -5961
ALG11 -5957
COG3 -5948
PRKCSH -5934
NAPA -5921
ST3GAL1 -5905
KDELR2 -5893
MGAT5 -5854
ARF4 -5812
SEC31A -5766
RENBP -5761
CSNK1D -5722
PSMC1 -5564
EDEM2 -5520
SEC24B -5475
UBXN1 -5450
PGM3 -5395
TFG -5336
GOLGA2 -5310
STX5 -5300
PPP6C -5241
PMM2 -5187
ACTR1A -5162
COPG1 -5135
FUT8 -5134
KDELR1 -5094
UBA52 -5068
MGAT4A -5018
DOLPP1 -4988
GBF1 -4981
SPTBN1 -4901
YKT6 -4899
CAPZA1 -4855
B4GALT3 -4852
AREG -4847
NSF -4839
ST6GALNAC6 -4820
ARFGAP3 -4817
ANK1 -4656
TRAPPC2L -4576
ST3GAL2 -4518
TGFA -4511
CTSC -4446
ALG1 -4352
UBB -4263
COG2 -4254
NUDT14 -4170
COPB1 -4098
TMED3 -4057
TRAPPC3 -4032
COG5 -3964
COPA -3958
DCTN2 -3957
DYNC1LI2 -3897
NAPG -3872
DCTN5 -3634
DYNC1H1 -3614
MAN1B1 -3561
USO1 -3509
GOLGB1 -3498
RAB1B -3479
LMAN1 -3431
LMAN2L -3429
GMDS -3350
MGAT2 -3327
RAB1A -3307
ST3GAL6 -3252
CD59 -3245
ALG14 -3206
RNF139 -3064
ASGR2 -2985
SAR1B -2973
NGLY1 -2909
DYNC1I2 -2780
RPS27A -2773
SEC23A -2717
AMFR -2698
PMM1 -2658
DYNC1LI1 -2519
B4GALT2 -2487
ARF3 -2430
MAN2A2 -2336
MOGS -2275
DPM2 -2111
CNIH3 -1958
DCTN4 -1937
EDEM3 -1903
ASGR1 -1889
ST6GAL1 -1828
ST8SIA5 -1758
SEC22C -1684
DCTN1 -1635
ARFGAP1 -1587
CAPZA2 -1549
DPM1 -1233
TUSC3 -1219
CAPZB -1169
MAN2A1 -1040
MAN1A1 -1021
UAP1 -898
PPP6R3 -623
ALG9 -426
NAPB -419
DCTN6 -318
B4GALT1 -262
DOLK 108
CNIH1 212
TRAPPC5 239
ANK3 303
SEC23IP 390
BET1 457
NANP 483
SCFD1 485
GOSR1 621
F8 735
UBC 779
COPZ1 782
F5 831
SEC22B 859
KDELR3 976
ALG8 1117
GOSR2 1238
ARFGAP2 1283
ALG13 1348
B4GALNT2 1387
UGGT2 1425
PREB 1446
DCTN3 1457
GLB1 1557
MGAT4C 1714
TRAPPC4 1781
TRIM13 1883
GORASP1 1903
COG4 1972
ST8SIA1 2289
SPTAN1 2385
GNPNAT1 2394
DHDDS 2399
DYNLL1 2509
FUOM 2573
TRAPPC6B 2584
STX17 2586
B4GALT4 2602
ALG10 2654
FUCA1 2696
GANAB 2813
B4GALT6 2881
MAN1C1 3072
TRAPPC1 3089
RAD23B 3141
DPM3 3217
COG6 3264
SEC22A 3312
BET1L 3487
TRAPPC2 3547
MPDU1 3718
SPTBN2 3883
SLC35A1 3906
SERPINA1 4014
ANKRD28 4146
MANEA 4202
NAGK 4508
COG1 4586
ARF5 4743
SRD5A3 4758
COG7 4792
ALG6 4943
TRAPPC9 5033
MPI 5076
RFT1 5083
ST3GAL5 5090
COL7A1 5362
AMDHD2 5414
ACTR10 5570
FPGT 5627
CMAS 5724
ALG10B 5899
ST3GAL3 5918
DYNLL2 6044
GNE 6051
COPG2 6142
ENGASE 6457
SEC16B 6744
COG8 6745
B4GALT5 6846
CHST10 6919
NEU4 6950
NEU3 7085
TRAPPC6A 7244
MVD 7302



Axon guidance

Axon guidance
87
set Axon guidance
setSize 424
pANOVA 2.94e-16
s.dist -0.232
p.adjustANOVA 6.75e-14



Top enriched genes

Top 20 genes
GeneID Gene Rank
VASP -7075
ABLIM1 -7055
RPL36AL -6981
ETF1 -6952
RNPS1 -6938
ARHGEF28 -6925
SHC1 -6910
MET -6878
RANBP9 -6871
EPHA2 -6857
ACTG1 -6841
GSPT1 -6825
ANK2 -6778
SEMA6A -6761
RHOC -6747
SCN2A -6712
SIAH2 -6666
PSMF1 -6663
MYL12B -6653
WASL -6543

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
VASP -7075
ABLIM1 -7055
RPL36AL -6981
ETF1 -6952
RNPS1 -6938
ARHGEF28 -6925
SHC1 -6910
MET -6878
RANBP9 -6871
EPHA2 -6857
ACTG1 -6841
GSPT1 -6825
ANK2 -6778
SEMA6A -6761
RHOC -6747
SCN2A -6712
SIAH2 -6666
PSMF1 -6663
MYL12B -6653
WASL -6543
DNM2 -6535
DPYSL2 -6519
ITGA10 -6466
PSME4 -6450
ARHGAP35 -6446
CLTA -6439
PSMD2 -6435
MYL6 -6380
PLXNA3 -6318
ARHGAP39 -6303
PFN1 -6285
UNC5B -6252
CLTC -6220
ITGA2 -6205
FGFR1 -6191
UPF3A -6189
TLN1 -6146
PRNP -6115
ARPC4 -6094
MAP2K2 -6087
CLTB -6064
CASC3 -5986
PSMD6 -5951
MYO9B -5920
EIF4G1 -5901
EFNA1 -5830
PSMA2 -5801
CFL1 -5737
PSMA1 -5730
PLXND1 -5686
CACNA1D -5676
PITPNA -5591
GIT1 -5582
ROBO1 -5577
PSMC1 -5564
HRAS -5543
MAPK12 -5538
PSMD3 -5535
GRB10 -5504
PSME2 -5481
IRS2 -5461
SOS2 -5417
EGFR -5383
PAK4 -5359
PSMD1 -5351
TRIO -5341
NRP2 -5313
ACTR3 -5296
RHOA -5294
MYO10 -5290
ZSWIM8 -5267
ARHGEF11 -5260
RPL19 -5254
NUMB -5224
PSPN -5177
EPHB1 -5141
RPS7 -5138
GSK3B -5101
UBA52 -5068
MAPK1 -5066
ACTB -5057
CSNK2A1 -5040
RPL11 -5032
RPL10 -5026
RPS15 -5010
RAP1GAP -4998
FAU -4990
RPL14 -4978
PAK2 -4957
PSEN1 -4938
SPTBN1 -4901
PSMB6 -4888
PSMC6 -4878
PSMC4 -4808
RPS5 -4778
PIK3CD -4759
MYH9 -4726
RPS11 -4702
MMP2 -4677
RPS19 -4661
ANK1 -4656
HSPA8 -4654
RPS28 -4652
VAV3 -4642
PSMD9 -4638
AP2M1 -4603
CSNK2A2 -4546
EZR -4464
ARPC1B -4429
HSP90AB1 -4426
RPLP1 -4391
MAPK7 -4382
EPHB4 -4379
PIK3R1 -4376
PSMB7 -4372
RPS12 -4367
PTK2 -4346
ITGAV -4312
RPL27A -4297
RPLP0 -4290
UBB -4263
CLASP2 -4246
PSMA4 -4211
RPL35A -4159
ITGB1 -4145
GAB2 -4127
MAP2K1 -4120
LYPLA2 -4095
PSMC5 -4091
CAP1 -4085
RPL30 -4081
PPP3CB -4060
RPS9 -4028
GRB7 -4006
GDNF -3969
RPL18 -3961
NCK2 -3916
CACNA1H -3915
RPL26L1 -3873
DLG1 -3865
RPS6KA1 -3857
RPS29 -3844
RPL6 -3843
UPF2 -3830
NRCAM -3815
PLXNA2 -3814
PSME3 -3813
FRS2 -3790
SHC3 -3782
PLXNB3 -3778
RBX1 -3714
ROCK1 -3594
RPL28 -3546
PABPC1 -3543
RPSA -3520
AP2A2 -3499
EFNB2 -3470
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
MYL12A -3398
RPS17 -3369
RPS24 -3352
SIAH1 -3347
SEMA7A -3299
RPS14 -3261
PIP5K1C -3229
RPS27L -3180
RPS10 -3155
ENAH -3139
SEM1 -3130
PSMA3 -3078
GRB2 -3047
LYN -3038
RPS6KA3 -3030
ABL2 -3020
RPS15A -3019
ELOB -3004
DOK6 -2987
RPL7 -2984
RPL34 -2974
PSMD8 -2928
RPS21 -2927
AP2S1 -2922
ARHGEF7 -2913
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
DSCAML1 -2830
PIK3CA -2813
RPS27A -2773
ROCK2 -2772
PSMA5 -2715
DOK4 -2697
CAP2 -2694
RPL23A -2692
RPL10A -2689
RPS6 -2681
ADAM10 -2671
RPS18 -2648
PDLIM7 -2636
RPL41 -2635
PIK3CB -2588
RPS13 -2581
PSMD13 -2577
RPL4 -2563
PSEN2 -2559
RPS23 -2467
RPL37A -2451
PSMC2 -2389
AGRN -2369
PSME1 -2348
PSENEN -2327
PIK3R3 -2279
RPL39 -2270
RPL18A -2240
RPL7A -2233
ARPC2 -2209
DAG1 -2174
CDC42 -2172
NCBP1 -2151
RPS4Y1 -2120
RPL27 -2070
KRAS -2044
NTN4 -1999
PSMB3 -1915
RPL23 -1913
AP2A1 -1902
MAPK13 -1875
SDCBP -1822
RPL24 -1804
SRGAP1 -1796
RPL38 -1791
SRGAP2 -1779
RPS20 -1754
RPL26 -1747
RBM8A -1583
RRAS -1578
ARPC5 -1511
PSMC3 -1509
PRKACB -1429
RND1 -1410
PIK3R2 -1355
CDK5 -1352
YES1 -1340
RPL15 -1313
LAMC1 -1300
EFNA3 -1228
RPL3 -1165
RPS6KA2 -1149
PSMB4 -1144
RPL17 -1119
ARHGEF12 -1086
RPS8 -1071
PLXNA1 -1050
PLXNB1 -1046
HSP90AA1 -1030
RPL12 -983
MAGOH -969
SOS1 -950
RPS25 -937
SH3KBP1 -917
L1CAM -904
PSMA7 -892
PTPN11 -867
PRKAR2A -860
PSMB5 -742
RPL13 -706
MAPK8 -700
ITGA2B -688
RELN -662
NCSTN -554
RPL5 -495
GRIN1 -442
PSMD11 -432
KALRN -408
SCN11A -295
RPL22L1 -214
RPS3A -179
CDK5R1 -157
RPS27 -152
PSMA6 -126
RAC1 44
SDC2 147
ITSN1 159
CNTN2 200
SCN8A 249
MAPK11 251
RPL9 261
ANK3 303
RPL31 330
CUL2 359
RPS26 419
PSMB10 423
CREB1 474
SHTN1 547
ITGA5 587
APH1A 619
ELOC 645
RPS6KA4 731
UBC 779
PTPRA 815
SLIT1 886
SHANK3 935
ARTN 973
RDX 1011
MYH11 1015
PAK1 1031
PSMB1 1054
EIF4A3 1154
LAMA1 1285
RGMB 1321
GRIN2B 1330
NRP1 1353
RPL21 1385
ACTR2 1435
NCK1 1525
DPYSL4 1531
CLASP1 1561
LIMK1 1565
GAB1 1575
EPHA10 1725
EFNA2 1735
PRKACA 1736
PSMB2 1876
LDB1 1882
USP33 1924
FYN 1937
CACNB4 1983
ABL1 2023
AP2B1 2029
COL6A3 2085
RPL22 2142
MAPK14 2269
NRAS 2310
UPF3B 2326
SPTAN1 2385
SCN1B 2398
PRKCA 2439
EVL 2467
SCN3B 2499
PLCG1 2511
MYH10 2558
RASA1 2559
ABLIM3 2675
MYL9 2704
HOXA2 2735
VAV2 2817
RPL36A 2875
CACNB1 2967
VLDLR 3001
ARPC1A 3022
AKAP5 3035
RPS6KA5 3086
ALCAM 3171
RGMA 3210
COL6A2 3222
EFNB3 3419
EFNB1 3480
SCN9A 3533
DOCK1 3540
TRPC1 3602
EFNA4 3658
FARP2 3688
CACNB3 3735
LAMB1 3783
ARPC3 3797
NRTN 3870
SPTBN2 3883
RPS6KA6 3918
SRC 3962
SEMA3A 4001
NEO1 4016
DOK1 4072
PSMD12 4303
PLXNC1 4319
MSI1 4326
GFRA3 4393
AGAP2 4399
CSNK2B 4415
TIAM1 4452
PSMD4 4567
ROBO3 4691
PSMD10 4933
PSMD7 4942
EPHA1 4960
DLG4 5108
PSMD5 5116
ITGA1 5152
DLG3 5168
GPC1 5178
CD24 5327
PSMB9 5491
MYH14 5492
FES 5506
ERBB2 5534
MAGOHB 5814
PSMD14 5974
KIF4A 6056
RHOB 6064
APH1B 6168
ABLIM2 6389
LIMK2 6394
CLTCL1 6404
SEMA4D 6479
DNM1 6505
MAPK3 6640
COL4A5 6694
SRGAP3 6775
NCBP2 6823
PFN2 6877
NGEF 7064
COL9A3 7151
FLRT3 7184
CNTNAP1 7239
COL6A1 7322
SCN1A 7327
COL9A2 7348



Cellular response to starvation

Cellular response to starvation
154
set Cellular response to starvation
setSize 149
pANOVA 2.02e-14
s.dist -0.363
p.adjustANOVA 3.98e-12



Top enriched genes

Top 20 genes
GeneID Gene Rank
ATP6V0B -7064
DDIT3 -7047
FLCN -7022
RRAGC -7009
RPL36AL -6981
ATP6V1D -6922
ATP6V0D1 -6908
SEC13 -6812
TRIB3 -6798
FNIP1 -6782
RRAGD -6743
ATP6V0E1 -6622
SESN2 -6610
ATP6V1E1 -6271
ATF2 -6175
ATP6V0C -6086
CEBPG -5987
ATP6V1C2 -5929
ATF4 -5664
ATP6V1B2 -5574

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ATP6V0B -7064
DDIT3 -7047
FLCN -7022
RRAGC -7009
RPL36AL -6981
ATP6V1D -6922
ATP6V0D1 -6908
SEC13 -6812
TRIB3 -6798
FNIP1 -6782
RRAGD -6743
ATP6V0E1 -6622
SESN2 -6610
ATP6V1E1 -6271
ATF2 -6175
ATP6V0C -6086
CEBPG -5987
ATP6V1C2 -5929
ATF4 -5664
ATP6V1B2 -5574
SLC38A9 -5539
FNIP2 -5498
ATP6V1G1 -5352
LAMTOR5 -5293
RPL19 -5254
EIF2S1 -5190
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
DEPDC5 -4989
RPL14 -4978
ATP6V1C1 -4946
RRAGB -4819
RPS5 -4778
RPS11 -4702
RPS19 -4661
RPS28 -4652
GCN1 -4627
SEH1L -4472
EIF2S2 -4458
ATP6V1H -4423
RPLP1 -4391
RPS12 -4367
RPL27A -4297
RPLP0 -4290
RPL35A -4159
RPL30 -4081
RPS9 -4028
RPL18 -3961
RPL26L1 -3873
RPS29 -3844
RPL6 -3843
ATP6V1A -3777
RHEB -3762
MTOR -3683
EIF2S3 -3669
RPL28 -3546
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
SH3BP4 -3331
RPS14 -3261
RPS27L -3180
RPS10 -3155
RPS15A -3019
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
RPS27A -2773
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
LAMTOR3 -2631
RPS13 -2581
RPL4 -2563
RPS23 -2467
RPL37A -2451
RPL39 -2270
RPL18A -2240
RPL7A -2233
RPS4Y1 -2120
RPL27 -2070
RPL23 -1913
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
EIF2AK4 -1455
RPL15 -1313
RPL3 -1165
CEBPB -1129
RPL17 -1119
RPS8 -1071
RPL12 -983
RPS25 -937
ATP6V1F -868
LAMTOR1 -774
RPL13 -706
ATP6V1E2 -534
RPL5 -495
RPL22L1 -214
RPS3A -179
RPS27 -152
LAMTOR2 -148
TCIRG1 180
RPL9 261
RPL31 330
RPTOR 407
RPS26 419
BMT2 638
ATP6V1G2 690
ATP6V0D2 747
RPL21 1385
LAMTOR4 1834
MLST8 1875
RPL22 2142
ITFG2 2143
ATF3 2488
RRAGA 2609
RPL36A 2875
MIOS 2912
NPRL3 4164
IMPACT 4432
WDR24 4466
KPTN 4478
ATP6V1B1 4549
NPRL2 4876
WDR59 4915
SESN1 4963
SZT2 5052
ATP6V0E2 5683
ASNS 6208



Metabolism of proteins

Metabolism of proteins
630
set Metabolism of proteins
setSize 1550
pANOVA 3.25e-14
s.dist -0.118
p.adjustANOVA 5.59e-12



Top enriched genes

Top 20 genes
GeneID Gene Rank
CALR -7142
RAB17 -7135
SEC24D -7134
DNAJC3 -7131
HSP90B1 -7129
SEL1L -7124
SELENOS -7117
SYVN1 -7108
PDIA6 -7106
EDEM1 -7103
WFS1 -7096
KLF4 -7093
CANX -7092
PDIA3 -7086
ERO1B -7079
SLC17A5 -7072
TMED2 -7071
KLHL21 -7069
MCFD2 -7065
ARRB1 -7062

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CALR -7142
RAB17 -7135
SEC24D -7134
DNAJC3 -7131
HSP90B1 -7129
SEL1L -7124
SELENOS -7117
SYVN1 -7108
PDIA6 -7106
EDEM1 -7103
WFS1 -7096
KLF4 -7093
CANX -7092
PDIA3 -7086
ERO1B -7079
SLC17A5 -7072
TMED2 -7071
KLHL21 -7069
MCFD2 -7065
ARRB1 -7062
GCNT3 -7052
GFPT1 -7051
MIA3 -7049
DERL2 -7046
MAGT1 -7045
SEC61A1 -7030
WSB2 -7029
RPN1 -7013
SSR4 -7004
FUT3 -7001
TRAM1 -6997
EIF4A1 -6995
SEC11C -6991
OS9 -6986
RPL36AL -6981
EIF3A -6965
ASB2 -6960
SEC61B -6958
UGGT1 -6954
ETF1 -6952
ARSB -6939
TGFB1 -6934
TMED7 -6933
SSR3 -6928
SSR1 -6907
NANS -6906
MLEC -6902
SRPRB -6893
P4HB -6884
BMP4 -6869
VGF -6864
GMPPB -6844
SEC24A -6839
GSPT1 -6825
SLC30A7 -6817
SEC13 -6812
ST3GAL4 -6801
STT3A -6796
POMT2 -6788
SPCS3 -6781
ANK2 -6778
TMEM115 -6764
SSR2 -6759
NEU1 -6752
MBD6 -6742
ST6GALNAC4 -6726
PPARA -6722
VCP -6720
CSF1 -6711
RAB43 -6699
FURIN -6683
DPP4 -6681
GBA -6674
SLC35C1 -6667
SIAH2 -6666
DDX5 -6665
PSMF1 -6663
LGALS1 -6649
SOCS5 -6643
KIF5A -6634
RNF5 -6629
UIMC1 -6627
RAB20 -6619
ALG3 -6601
SERPINC1 -6588
TRAPPC10 -6585
FOXK2 -6570
LMAN2 -6558
ALG2 -6554
USP16 -6545
FUCA2 -6538
COPB2 -6532
RAB22A -6525
CD55 -6517
PPP6R1 -6511
ARCN1 -6505
TMED9 -6502
APP -6492
VHL -6491
KEAP1 -6482
TOP1 -6472
ALG5 -6471
EP300 -6470
MAN1A2 -6460
PSME4 -6450
NFKBIA -6437
PSMD2 -6435
ADRA2C -6434
DDOST -6429
DERL1 -6423
SRP68 -6420
SPON2 -6404
MGAT1 -6401
MTRF1L -6400
NUS1 -6395
GATA4 -6369
SRP19 -6363
RNF185 -6359
THSD4 -6356
POM121 -6353
GMPPA -6346
APOA2 -6307
TIMP1 -6294
CTSA -6288
MGAT4B -6279
RARA -6269
CCT5 -6251
DAD1 -6240
KIFC3 -6237
SEC24C -6236
TTLL11 -6233
UBE2J2 -6232
STC2 -6224
TECTB -6219
TBC1D20 -6203
RPN2 -6193
PIGG -6186
SAFB -6184
SMAD3 -6145
DCAF11 -6142
YOD1 -6141
GGA2 -6138
RNF103 -6135
LONP2 -6122
TMED10 -6116
ALG12 -6081
CYLD -6066
EIF5 -6065
HCFC1 -6060
DPAGT1 -6046
POM121C -6045
NR1H4 -6037
ARF1 -6021
RAB9A -6014
JOSD1 -5993
SEC16A -5971
WAC -5965
COPE -5961
MBTPS1 -5958
ALG11 -5957
PSMD6 -5951
COG3 -5948
IKBKG -5946
FBXW5 -5945
OTUD5 -5944
SRP14 -5938
PRKCSH -5934
SPCS2 -5930
CCT2 -5926
NAPA -5921
GNA11 -5916
ST3GAL1 -5905
EIF4G1 -5901
EIF4B -5898
ZRANB1 -5895
KDELR2 -5893
MUL1 -5892
UBE2F -5885
SIN3A -5884
PCGF2 -5881
RORA -5875
SPP1 -5872
PPARGC1A -5869
CCT6A -5862
MGAT5 -5854
ASXL2 -5845
DCUN1D3 -5821
ARF4 -5812
RAB7A -5810
PSMA2 -5801
RIPK2 -5779
SEC31A -5766
UBE2G1 -5763
RENBP -5761
AXIN2 -5745
PSMA1 -5730
CSNK1D -5722
PCMT1 -5697
DDB1 -5688
MRPS6 -5687
EIF5A -5678
VCAN -5649
DDA1 -5633
DPH2 -5629
CCT8 -5605
PSMC1 -5564
NR5A2 -5547
PSMD3 -5535
SRP72 -5526
EDEM2 -5520
CDC34 -5516
TRIM25 -5492
FBXO31 -5485
PSME2 -5481
SEC24B -5475
SOCS6 -5467
RNF40 -5459
UBXN1 -5450
USP2 -5430
KIF5B -5426
B3GLCT -5422
DCAF10 -5421
PTRH2 -5409
RAB5A -5408
DPH1 -5397
PGM3 -5395
RAB2A -5379
MRPS15 -5376
PNPLA2 -5366
PSMD1 -5351
CPE -5338
TFG -5336
THSD1 -5333
GOLGA2 -5310
STX5 -5300
FBXO32 -5299
RHOA -5294
PUM2 -5288
RAB32 -5287
EIF3I -5279
PIGW -5277
NUP205 -5275
RAB35 -5270
USP22 -5265
RPL19 -5254
SMURF2 -5253
FSTL3 -5252
TPGS1 -5251
ASB6 -5243
PPP6C -5241
MRPL38 -5234
UCHL3 -5231
YY1 -5214
RABGGTB -5199
EIF2S1 -5190
PMM2 -5187
TADA2B -5182
SENP5 -5170
ACTR1A -5162
COPS2 -5161
MRPS2 -5145
RPS7 -5138
COPG1 -5135
FUT8 -5134
EIF3B -5127
EEF1D -5115
USP42 -5109
NUCB1 -5103
AURKAIP1 -5100
KDELR1 -5094
VAMP2 -5088
PTP4A2 -5085
MRPS12 -5083
DPH3 -5074
UBA52 -5068
ACTB -5057
LARGE1 -5056
EIF4H -5055
MRPL3 -5054
EEF2 -5049
VCPIP1 -5042
CSNK2A1 -5040
RPL11 -5032
RPL10 -5026
PIAS4 -5022
RAB40C -5019
MGAT4A -5018
CD109 -5016
RPS15 -5010
RPA1 -5008
KIF13A -4995
NUP188 -4991
FAU -4990
DOLPP1 -4988
GBF1 -4981
RPL14 -4978
MRPL47 -4976
BPIFB2 -4967
ATXN7 -4932
EIF5A2 -4929
COMMD5 -4916
EPAS1 -4915
SPTBN1 -4901
YKT6 -4899
COPS8 -4894
PSMB6 -4888
WSB1 -4879
PSMC6 -4878
RAB31 -4876
KLHL42 -4874
MRPL14 -4864
SNX3 -4858
CAPZA1 -4855
B4GALT3 -4852
AREG -4847
NSF -4839
EIF2B5 -4838
EEF1B2 -4836
TRIM27 -4835
ST6GALNAC6 -4820
ARFGAP3 -4817
RNF181 -4815
EIF2B2 -4811
PSMC4 -4808
SRPRA -4802
MRPL23 -4800
KAT2B -4792
TNKS -4790
TGFBI -4782
GOLM1 -4779
RPS5 -4778
NUP88 -4777
CCDC59 -4775
FEM1C -4764
GALNT10 -4763
SPSB3 -4739
TCP1 -4735
NUP50 -4733
EIF3G -4724
PTEN -4721
EVA1A -4709
RPS11 -4702
FBXO44 -4694
CUL4B -4685
CDC73 -4683
RNF123 -4681
NR5A1 -4679
MMP2 -4677
RABGGTA -4673
NCOA1 -4665
RPS19 -4661
SP3 -4660
ANK1 -4656
HSPA8 -4654
RPS28 -4652
KDM1B -4647
PSMD9 -4638
TSPAN14 -4626
COPS3 -4618
MRPL34 -4611
DCUN1D2 -4601
MRPL41 -4594
TRAPPC2L -4576
MRPL35 -4563
GPLD1 -4556
DCAF5 -4547
CSNK2A2 -4546
EIF3J -4539
MRPL32 -4532
ARSD -4527
CALU -4521
ST3GAL2 -4518
GNB2 -4514
TGFA -4511
INHBE -4510
NSMCE2 -4496
MRPS18C -4493
SEH1L -4472
BCL10 -4471
MRPL51 -4467
EIF2S2 -4458
MRPL46 -4455
CTSC -4446
MBD1 -4444
USP34 -4441
TNIP1 -4433
STS -4430
NCOR2 -4409
RPLP1 -4391
PSMB7 -4372
CBX8 -4370
RPS12 -4367
EIF3M -4358
ALG1 -4352
USP15 -4344
UBE2M -4337
MRPS24 -4327
FOXK1 -4324
USP9X -4318
POLB -4316
B3GNT9 -4301
RPL27A -4297
RPLP0 -4290
PHC1 -4280
PIGA -4278
UBB -4263
DOHH -4258
COG2 -4254
TRIM4 -4229
AXIN1 -4215
PSMA4 -4211
HGS -4210
MRPL33 -4189
BMI1 -4180
ASB1 -4171
NUDT14 -4170
HIF1A -4165
P2RY2 -4163
RPL35A -4159
AFP -4151
EEF1A1 -4138
CUL1 -4129
COPB1 -4098
MRPL44 -4094
PSMC5 -4091
SMAD2 -4087
RPL30 -4081
RXRA -4073
MXRA8 -4064
CBX4 -4063
TMED3 -4057
SEC61G -4052
GALNT7 -4049
IDE -4045
TRAPPC3 -4032
RPS9 -4028
NFRKB -4026
GGCX -4023
EEF1E1 -4013
NR3C1 -4005
TULP4 -4002
UBE2D3 -3997
COG5 -3964
USP3 -3962
RPL18 -3961
COPA -3958
DCTN2 -3957
THRB -3951
FBXL20 -3941
CKAP4 -3939
WDR20 -3937
IGFBP1 -3931
TTR -3924
GADD45GIP1 -3917
POMT1 -3914
UBA2 -3913
MRPS22 -3909
EXOC3 -3898
DYNC1LI2 -3897
CTR9 -3895
ASB7 -3889
CREBBP -3888
RPL26L1 -3873
NAPG -3872
TRMT112 -3869
FBXO11 -3853
RPS29 -3844
RPL6 -3843
ASB4 -3822
PSME3 -3813
FBXW11 -3784
SLC30A5 -3771
NUP98 -3764
EIF3D -3740
HERC2 -3739
SENP2 -3731
RBX1 -3714
TOP2B -3712
B4GAT1 -3691
TTLL7 -3685
APOE -3670
EIF2S3 -3669
RAB15 -3665
TGFBR2 -3644
GAN -3641
PEX14 -3636
DCTN5 -3634
PFDN2 -3625
DYNC1H1 -3614
EEF1G -3612
TXN -3611
ZNF131 -3603
SORL1 -3586
TRRAP -3581
RNF168 -3576
MAN1B1 -3561
ADRM1 -3551
KCTD7 -3550
RPL28 -3546
PABPC1 -3543
COMMD9 -3531
RPSA -3520
USO1 -3509
GPS1 -3506
MYO5A -3500
GOLGB1 -3498
USP12 -3488
RAB1B -3479
ADAMTSL2 -3475
RPL8 -3467
RPS4X -3464
RPS2 -3462
TUFM -3458
RPL29 -3450
RPL32 -3448
RPL36 -3432
LMAN1 -3431
LMAN2L -3429
XRN2 -3427
RPL37 -3413
INO80 -3397
RPS17 -3369
RPS24 -3352
GMDS -3350
SIAH1 -3347
MRPS18B -3346
STAG1 -3341
APLP2 -3330
MGAT2 -3327
MDC1 -3323
DDX17 -3321
INO80D -3312
RAB1A -3307
TBCD -3294
MRPS36 -3292
VBP1 -3287
KLHL2 -3269
RPS14 -3261
ST3GAL6 -3252
ARRB2 -3248
CD59 -3245
GNB1 -3237
GALNT3 -3227
KTN1 -3223
TNKS2 -3213
ALG14 -3206
RPS27L -3180
PPARG -3168
ACTR8 -3157
RPS10 -3155
UBE2L3 -3143
SPHK1 -3142
SEM1 -3130
RAB5C -3129
FN1 -3115
MBD5 -3114
TDG -3113
TRIM28 -3099
LEO1 -3088
PSMA3 -3078
RNF139 -3064
COPS6 -3063
CUL3 -3056
SEC11A -3046
COPS5 -3031
RPS15A -3019
MRPL54 -3013
ELOB -3004
MRPL37 -2997
THRA -2996
ASGR2 -2985
RPL7 -2984
GPR119 -2983
RAB33B -2981
FARSA -2976
RPL34 -2974
SAR1B -2973
APOB -2964
MRPL36 -2957
C1GALT1C1 -2939
SATB2 -2932
PSMD8 -2928
RPS21 -2927
CCT3 -2912
NGLY1 -2909
BECN1 -2900
RPS16 -2898
RIPK1 -2886
RPS3 -2880
TPST2 -2873
RPL13A -2872
VDAC2 -2869
RPLP2 -2863
LARGE2 -2856
RPL35 -2849
USP5 -2837
GFM1 -2827
USP8 -2820
HNRNPK -2808
TOMM70 -2797
USP24 -2786
IGFBP6 -2783
PFDN5 -2781
DYNC1I2 -2780
RPS27A -2773
BAP1 -2760
TOPORS -2753
UHRF2 -2752
MRRF -2721
SEC23A -2717
MRPL57 -2716
PSMA5 -2715
MRPS34 -2704
AMFR -2698
EID3 -2695
RPL23A -2692
RPL10A -2689
RPS6 -2681
HDAC1 -2676
ADAM10 -2671
MRPS23 -2664
PMM1 -2658
UBE2E3 -2654
RPS18 -2648
TTL -2640
RPL41 -2635
RELA -2632
TGFBR1 -2620
STAG2 -2617
FBXL14 -2614
MRPL48 -2613
HIC1 -2592
UBE2B -2586
CYR61 -2582
RPS13 -2581
PSMD13 -2577
GFM2 -2567
FBXW7 -2564
RPL4 -2563
MDM4 -2561
FBXW10 -2540
B2M -2523
DYNC1LI1 -2519
PARK7 -2508
OTULIN -2499
B4GALT2 -2487
MRPS28 -2470
DCAF6 -2469
RPS23 -2467
SP100 -2455
RPL37A -2451
ADAMTS17 -2445
ARF3 -2430
B3GALNT2 -2427
USP19 -2419
MRPL39 -2415
ERCC8 -2409
EIF3L -2407
GPAA1 -2406
PSMC2 -2389
STX1A -2377
B3GNT2 -2359
PSME1 -2348
OTUD3 -2342
CDH2 -2339
MAN2A2 -2336
PSENEN -2327
INHBB -2320
DPH7 -2301
PRKDC -2300
SUDS3 -2287
MOGS -2275
MRPS11 -2271
RPL39 -2270
UBA6 -2266
CUL4A -2265
RAB8A -2247
RPL18A -2240
RPL7A -2233
EIF3K -2206
DAG1 -2174
TSPAN5 -2154
RAB4A -2148
TPST1 -2126
RPS4Y1 -2120
DPM2 -2111
FBXL19 -2110
TGOLN2 -2105
SMC5 -2095
FOXO4 -2077
RPL27 -2070
NPM1 -2033
FBXL3 -2027
MRPL22 -2025
CCNE2 -2024
RFWD2 -2022
TP53 -2020
UBE2W -1973
SRP54 -1969
CNIH3 -1958
DCTN4 -1937
NUP214 -1926
MRPL4 -1923
SVBP -1922
PSMB3 -1915
RPL23 -1913
OTUD7B -1911
ASXL1 -1908
LTBP1 -1904
EDEM3 -1903
DCUN1D5 -1895
ASGR1 -1889
PIGH -1877
UBE2S -1872
USP47 -1849
FBXO9 -1843
B3GNT4 -1829
ST6GAL1 -1828
VARS2 -1827
ZDHHC2 -1819
APC -1818
RPL24 -1804
RPL38 -1791
RAB39B -1774
IARS2 -1767
ST8SIA5 -1758
RPS20 -1754
RTF1 -1751
RPL26 -1747
EEF1A1P5 -1745
RAB3B -1738
MSRA -1733
CCDC22 -1703
SEC22C -1684
USP28 -1668
CAND1 -1658
MRPS30 -1657
DCTN1 -1635
ARFGAP1 -1587
FEM1A -1576
PPA1 -1553
CAPZA2 -1549
MUC13 -1524
PSMC3 -1509
FBXL18 -1507
NDC1 -1490
HDAC4 -1478
MCRS1 -1472
CCT7 -1465
NSMCE4A -1462
MRPS35 -1461
CCT4 -1418
SEC61A2 -1397
MRPL53 -1391
RAB2B -1387
PIAS3 -1381
ACTL6A -1378
RNF128 -1375
SOCS2 -1346
MYRIP -1341
PIGN -1322
CHD3 -1321
UBE2I -1318
TNIP2 -1314
RPL15 -1313
NFKB2 -1311
SPSB2 -1306
WDTC1 -1303
LAMC1 -1300
TUBA8 -1280
UBA3 -1275
ARSK -1251
QSOX1 -1250
LMO7 -1246
ATP6AP2 -1245
DPM1 -1233
CUL5 -1229
KLHL11 -1223
TUSC3 -1219
TADA3 -1216
CAPZB -1169
RPL3 -1165
PIGT -1154
ACHE -1152
NOP56 -1145
PSMB4 -1144
FBXL12 -1137
RCE1 -1124
RPL17 -1119
TUBB6 -1115
ASB8 -1103
TSFM -1098
ADAMTSL5 -1090
RPS8 -1071
MAN2A1 -1040
VDAC1 -1027
TTLL9 -1023
MAN1A1 -1021
MUC20 -1019
GNB3 -1008
MRPS9 -1007
PDCL -1005
KLHL5 -991
RPL12 -983
UBE2Z -964
MDM2 -956
RPS25 -937
DDX58 -927
UBE2D2 -913
UAP1 -898
EIF3F -893
PSMA7 -892
SENP1 -886
MRPL18 -882
RAB11B -876
FBXL13 -870
COPS7B -839
GALNT1 -816
GALNT13 -810
IKBKE -787
EXOC2 -747
PSMB5 -742
MRPL9 -726
PEX13 -721
SFTPB -720
UBE2G2 -718
TTLL5 -713
ING2 -711
RPL13 -706
CALM1 -655
YARS2 -645
LRRC49 -625
PPP6R3 -623
MSRB3 -621
RNF7 -611
PIGS -609
ASB18 -601
TRAF2 -577
TTLL12 -556
NCSTN -554
SKP1 -544
MRPS18A -532
SARS2 -521
INHA -500
BIRC2 -499
RPL5 -495
LRR1 -494
PAX6 -478
MRPS10 -474
MRPL40 -473
PSMD11 -432
ALG9 -426
NAPB -419
MRPL50 -402
DCUN1D4 -400
UBE2R2 -386
EIF3C -374
RAB18 -372
TRAF3 -356
PEX5 -346
HDAC2 -338
NUP160 -329
USP25 -325
DCTN6 -318
NUP62 -299
LYPD3 -297
FBXW2 -294
OTUB1 -293
EIF1AX -274
VDAC3 -273
PIAS1 -272
POFUT2 -264
B4GALT1 -262
KLHL25 -215
RPL22L1 -214
ERO1A -198
INO80C -185
RPS3A -179
KCTD6 -178
MTIF3 -173
ANO8 -168
RPS27 -152
EIF2B1 -143
PSMA6 -126
FEM1B -103
RBBP5 -101
EXOC8 -92
FBXO2 -78
CTBP1 -41
COPS4 -28
RANBP2 -4
COMMD4 -2
FBXO10 18
AHSG 25
BTBD1 37
HDAC3 38
CSF2RA 43
PIGX 63
OTOA 87
MRPL19 96
DOLK 108
COMMD10 117
RNF135 126
HDAC7 130
USP7 134
FBXO30 137
SDC2 147
NR1H2 193
CNIH1 212
APOA4 226
TRAPPC5 239
BGLAP 241
RPL9 261
MITF 267
RAB30 288
ANK3 303
RPL31 330
EXOC5 337
SUZ12 346
CUL2 359
UBE2K 383
PIAS2 388
SEC23IP 390
COMMD2 395
RPS26 419
PSMB10 423
TUBB3 436
EIF2B4 437
UCHL5 443
WDR61 452
BET1 457
MRPL13 482
NANP 483
SCFD1 485
LAMB2 495
UBA1 516
NR2C1 535
WDR48 543
EEF1A2 553
CCT6B 563
TPR 565
NRIP1 570
NEDD8 580
OTUD7A 589
RAD21 601
FBXL15 612
APH1A 619
GOSR1 621
TAF10 626
F2 635
ELOC 645
PRSS23 655
MTIF2 664
TOMM20 676
GCNT1 679
TUBA4A 682
GNB5 700
COMMD8 710
BST1 713
F8 735
C1GALT1 742
MRPL20 773
UBC 779
COPZ1 782
SMC1A 784
MRPS14 785
MRPS5 787
L3MBTL2 789
GNAQ 803
GP2 806
RNF146 825
F5 831
PHC3 843
SEC22B 859
EEF2KMT 867
LMCD1 888
FBXW9 890
MRPS17 895
EIF3H 899
TBCE 923
FBXO7 947
PIGY 948
RAB12 950
TCF7L2 959
CAMKMT 962
DAP3 972
KDELR3 976
CEACAM5 1008
USP10 1016
ARFGEF2 1022
MRPL28 1039
PML 1051
EXOC4 1053
PSMB1 1054
CHCHD1 1058
MYSM1 1066
AIMP2 1067
PIGU 1074
SPSB1 1077
NSMCE3 1095
SUMF2 1101
ALG8 1117
UBXN7 1120
CPM 1144
TFPT 1213
AURKA 1224
GOSR2 1238
ADAMTS4 1241
USP20 1248
EARS2 1253
ARFGAP2 1283
TUBB2A 1290
CCNF 1291
RAB6A 1296
MEN1 1298
FN3K 1324
FARS2 1328
MRPL58 1346
ALG13 1348
NUP133 1362
MBOAT4 1368
RPL21 1385
BTRC 1386
B4GALNT2 1387
B3GNTL1 1392
RAB6B 1396
USP49 1405
MRPL15 1406
UGGT2 1425
DCUN1D1 1428
PAPPA 1432
PREB 1446
USP4 1449
DCTN3 1457
CALB1 1461
GSN 1496
PTCD3 1514
NR3C2 1520
GLB1 1557
SUMO2 1568
B3GNT7 1584
SPP2 1592
TRAF6 1597
RAB3D 1600
RAB10 1625
RAB29 1630
MRPL52 1657
MAVS 1695
MAT2B 1703
MGAT4C 1714
ITIH2 1740
CHML 1746
MRPS7 1777
TRAPPC4 1781
AIMP1 1790
SAE1 1799
TBCB 1809
MTA1 1810
HNRNPC 1814
PAF1 1828
UBE2N 1836
MSRB1 1864
AGBL3 1865
NEGR1 1869
PSMB2 1876
TRIM13 1883
MYC 1892
GORASP1 1903
USP33 1924
GNB4 1936
NAT8 1943
MARS2 1957
COG4 1972
LRRC41 1992
TTLL4 2011
ETFB 2051
CARS2 2078
FGF23 2097
NARS2 2113
PIGC 2130
DNMT1 2134
RPL22 2142
SMC6 2150
WRAP53 2169
ZNF350 2186
STAMBPL1 2213
CHGB 2226
INHBC 2246
KIF5C 2266
ST8SIA1 2289
PIGO 2315
METTL22 2346
ERAL1 2351
BRCC3 2358
NEURL2 2359
OXA1L 2372
TMEM132A 2376
NUP58 2380
MRPS27 2381
SPTAN1 2385
OBSL1 2391
GNPNAT1 2394
DHDDS 2399
TECTA 2402
PPA2 2403
USP48 2408
SPCS1 2416
GALNT4 2438
RNF2 2454
VASH1 2462
DARS2 2466
CCDC8 2470
EIF4E 2473
POMK 2475
GATA6 2495
EXOC6 2506
DYNLL1 2509
THBS2 2512
MRPL21 2518
GGA1 2520
SMC3 2546
WDR5 2561
FUOM 2573
DNAJC24 2574
TARS2 2575
TRAPPC6B 2584
STX17 2586
B4GALT4 2602
AGBL5 2606
RRAGA 2609
UBE2Q2 2642
ALG10 2654
PEX10 2668
ANKRD9 2692
RAB21 2694
FUCA1 2696
GAS6 2708
NUP153 2712
TUBB1 2717
RAB26 2740
SMAD4 2742
MRPL27 2747
CCNE1 2754
ACE2 2757
USP11 2763
HLA-B 2764
TBCC 2785
GALNT16 2794
USP21 2804
NUP43 2808
CTSD 2812
GANAB 2813
INO80B 2818
VWA1 2832
RGS9 2861
RPL36A 2875
ARSA 2878
ADAMTS7 2880
B4GALT6 2881
RAB5B 2913
FBXL8 2924
KBTBD8 2943
ADAMTSL3 2956
PFDN4 2960
AAAS 2965
PARP1 2974
BABAM1 2979
ICMT 2988
RAB27A 3011
ASB3 3026
WRN 3032
ABCA3 3033
MAN1C1 3072
STAM2 3080
TRAPPC1 3089
ALB 3096
FBXL22 3108
SMAD7 3117
RAD23B 3141
MTFMT 3156
RAB4B 3174
POMGNT1 3215
DPM3 3217
EIF3E 3244
MRPS26 3245
COG6 3264
FARSB 3269
CTNNB1 3272
SUMO1 3308
NUP54 3310
SEC22A 3312
EIF5B 3318
KLHL20 3344
DNMT3A 3360
UBE2V2 3369
XRCC4 3376
PIGP 3397
RCN1 3434
ZBED1 3448
RANGAP1 3458
UBD 3463
DHPS 3475
BIRC3 3477
BET1L 3487
UBE2D1 3523
EXOC7 3531
TRAPPC2 3547
FBXO15 3559
B3GNT8 3574
KIN 3578
FBXO27 3623
DAXX 3635
RAB14 3647
GCNT4 3690
CDKN2A 3704
KLHL9 3712
PHC2 3713
ATXN3 3714
FBXW8 3716
MPDU1 3718
RAB13 3724
ITM2B 3727
MRPL10 3731
CST3 3732
UBE2E1 3733
UBE2A 3752
MAP3K7 3767
ADAMTS1 3770
LAMB1 3783
USP37 3800
LYZ 3804
ETFBKMT 3805
JOSD2 3811
AP3M1 3816
DCAF17 3819
SPTBN2 3883
NUB1 3894
SLC35A1 3906
INO80E 3921
FBXO6 3932
TBCA 3995
SERPINA1 4014
RAB24 4024
TUBB8 4034
MRPL49 4062
RING1 4067
MRPL11 4075
WARS2 4080
NRN1L 4081
RHOT1 4106
APOA5 4116
GNG5 4123
ANKRD28 4146
ACTR5 4150
NUP85 4178
FBXO4 4180
TUBB2B 4184
GPC3 4191
GGA3 4199
PIGV 4200
MANEA 4202
SERPINA10 4206
TSPAN33 4207
TSPAN15 4238
SLC30A6 4251
STAT3 4253
MRPL12 4261
IGFBP7 4272
KLHL13 4291
PIGB 4297
PSMD12 4303
COMMD1 4304
RAB3A 4309
VCPKMT 4329
CPB2 4337
TNFAIP3 4359
CUL7 4377
RAE1 4394
CSNK2B 4415
GNG7 4426
RAB42 4442
HIF3A 4444
LY6E 4473
PLAUR 4485
POMGNT2 4488
RNF144A 4501
NAGK 4508
RAB11A 4527
PIGQ 4551
MSLN 4555
PSMD4 4567
PEX2 4569
DTL 4577
COG1 4586
SKIV2L 4599
PFDN1 4605
B3GNT3 4629
DCAF8 4645
DCAF13 4652
RAB40B 4658
RAB8B 4676
NR1H3 4678
ANPEP 4690
APEH 4698
MRPS33 4704
TUBA1A 4706
RAB23 4722
PEX12 4742
ARF5 4743
SRD5A3 4758
FBXO22 4762
NCOA2 4780
TP53BP1 4788
MRPL43 4791
COG7 4792
NUP155 4796
FBXL4 4801
PIGF 4815
MUC15 4828
NICN1 4839
SHISA5 4853
EIF4EBP1 4858
MRPS21 4888
APOL1 4896
SUMO3 4906
TMEM129 4918
PSMD10 4933
GALNT6 4939
PSMD7 4942
ALG6 4943
FAM20C 4945
RAB36 4950
SMAD1 4977
FBXO21 4978
COMMD3 4983
RTN4RL2 5004
TRAPPC9 5033
ADAMTS13 5043
IGFBP4 5060
MPI 5076
KAT2A 5077
RFT1 5083
KLHL22 5084
RARS2 5085
ST3GAL5 5090
BRCA1 5107
STAM 5109
PSMD5 5116
PFDN6 5123
ADORA2B 5127
RBBP7 5134
ASB9 5150
TTF1 5165
BIRC5 5174
COMMD7 5185
AGBL2 5191
EIF2B3 5203
USP14 5232
METTL21A 5233
PIGM 5248
CASP8AP2 5260
INCENP 5290
RUVBL1 5317
ADORA2A 5330
MRPL42 5341
DCAF16 5344
XPC 5353
H2AFX 5356
COL7A1 5362
UBE2H 5369
AMDHD2 5414
DCAF4 5420
CHM 5425
NOD1 5449
PSMB9 5491
DPH6 5513
PIGZ 5536
VNN1 5548
MFGE8 5552
DCAF7 5557
ACTR10 5570
EIF4A2 5593
SRP9 5604
NOP58 5612
TPGS2 5616
FPGT 5627
CDC20 5650
COPS7A 5653
CTSH 5655
NR1I2 5656
COMMD6 5668
FBXL5 5669
HARS2 5687
PRMT3 5707
UBE2T 5710
ARL2 5716
CMAS 5724
F10 5732
NAE1 5740
AARS2 5743
HLA-A 5777
UCN 5800
CETN2 5801
AGTPBP1 5818
MRPL55 5826
NUP93 5831
RNF20 5837
PIGL 5841
TF 5850
IGFALS 5854
MSRB2 5860
MRPL1 5865
STAMBP 5873
USP18 5875
MRPL16 5878
MRPS16 5883
ALG10B 5899
OTUB2 5916
ST3GAL3 5918
MRPL17 5943
VASH2 5945
SKP2 5946
PGAP1 5952
CDC25A 5954
HRC 5955
MRPL30 5960
PSMD14 5974
NUP35 5982
FBXO17 5986
THBS1 5988
BLM 5994
CISH 6003
FBXW4 6039
XPNPEP2 6043
DYNLL2 6044
RAD18 6045
GNE 6051
PROS1 6053
USP13 6054
IGFBP3 6060
NUP107 6076
BACE1 6090
TAF9B 6106
ARSI 6118
MRPL2 6122
LARS2 6133
SENP8 6135
FBXO41 6136
BARD1 6138
COPG2 6142
SHPRH 6150
GNG4 6164
APH1B 6168
SUMF1 6175
RAD52 6185
MRPS31 6190
CCP110 6203
PROZ 6212
PIGK 6215
FKBP8 6242
HIPK2 6284
EXOC1 6302
F7 6332
VNN3 6337
USP30 6349
IGFBP2 6370
ASB13 6386
ADAMTS9 6402
FN3KRP 6434
OGT 6452
ENGASE 6457
ADAMTS6 6501
PCNA 6523
GALNT2 6578
CCNA2 6594
RWDD3 6644
IFIH1 6646
CDCA8 6649
SCMH1 6656
NSMCE1 6680
ART4 6681
TAB1 6687
SERPIND1 6689
FGG 6697
PROC 6720
TTLL1 6723
DPH5 6731
SEC16B 6744
COG8 6745
DDB2 6754
TUBB4B 6758
TUBA1C 6761
HLTF 6769
KBTBD7 6772
CUL9 6773
GNG10 6779
NOTUM 6788
KBTBD6 6796
NUP210 6802
B4GALT5 6846
TOP2A 6875
AURKB 6883
CHST10 6919
ADAMTS2 6939
NEU4 6950
DNMT3B 6957
CBX2 6958
ADAMTS10 6971
MRPL24 6982
RAB37 6989
APOA1 6993
CLSPN 7014
CES1 7025
ADAMTSL4 7040
NEU3 7085
MRPS25 7089
AGT 7091
TUBA1B 7094
NUP37 7100
TTLL3 7102
FKBP9 7108
PARS2 7123
GALNT11 7125
RECK 7128
UBE2C 7137
RAD23A 7141
N6AMT1 7144
FBN1 7148
HSPG2 7157
CBX5 7222
CDK1 7230
TRAPPC6A 7244
FBXL16 7269
UBE2L6 7272
MELTF 7295
MATN3 7298
MVD 7302
ODAM 7310
CP 7325
FAM20A 7332
FGA 7336
ARSG 7341
C4A 7346
C3 7357
SOCS3 7374
IGF2 7375
MUC5B 7378
PLG 7380
PCSK9 7381
KNG1 7382



Nervous system development

Nervous system development
708
set Nervous system development
setSize 444
pANOVA 6.25e-14
s.dist -0.209
p.adjustANOVA 9.56e-12



Top enriched genes

Top 20 genes
GeneID Gene Rank
VASP -7075
ABLIM1 -7055
RPL36AL -6981
ETF1 -6952
RNPS1 -6938
ARHGEF28 -6925
SHC1 -6910
MET -6878
RANBP9 -6871
EPHA2 -6857
ACTG1 -6841
GSPT1 -6825
ANK2 -6778
SEMA6A -6761
RHOC -6747
SCN2A -6712
SIAH2 -6666
PSMF1 -6663
MYL12B -6653
WASL -6543

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
VASP -7075
ABLIM1 -7055
RPL36AL -6981
ETF1 -6952
RNPS1 -6938
ARHGEF28 -6925
SHC1 -6910
MET -6878
RANBP9 -6871
EPHA2 -6857
ACTG1 -6841
GSPT1 -6825
ANK2 -6778
SEMA6A -6761
RHOC -6747
SCN2A -6712
SIAH2 -6666
PSMF1 -6663
MYL12B -6653
WASL -6543
DNM2 -6535
DPYSL2 -6519
ITGA10 -6466
PSME4 -6450
ARHGAP35 -6446
CLTA -6439
PSMD2 -6435
MYL6 -6380
NAB2 -6372
PLXNA3 -6318
ARHGAP39 -6303
PFN1 -6285
UNC5B -6252
CLTC -6220
ITGA2 -6205
FGFR1 -6191
UPF3A -6189
TLN1 -6146
PRNP -6115
ARPC4 -6094
MAP2K2 -6087
CLTB -6064
CASC3 -5986
PSMD6 -5951
MYO9B -5920
EIF4G1 -5901
EFNA1 -5830
PSMA2 -5801
CFL1 -5737
PSMA1 -5730
PLXND1 -5686
CACNA1D -5676
PITPNA -5591
GIT1 -5582
ROBO1 -5577
PSMC1 -5564
HRAS -5543
MAPK12 -5538
PSMD3 -5535
GRB10 -5504
PSME2 -5481
IRS2 -5461
SOS2 -5417
EGFR -5383
PAK4 -5359
PSMD1 -5351
TRIO -5341
NRP2 -5313
ACTR3 -5296
RHOA -5294
MYO10 -5290
ZSWIM8 -5267
ARHGEF11 -5260
RPL19 -5254
NUMB -5224
PSPN -5177
EPHB1 -5141
RPS7 -5138
GSK3B -5101
UBA52 -5068
MAPK1 -5066
ACTB -5057
CSNK2A1 -5040
RPL11 -5032
RPL10 -5026
RPS15 -5010
RAP1GAP -4998
FAU -4990
RPL14 -4978
PAK2 -4957
PSEN1 -4938
SPTBN1 -4901
PSMB6 -4888
PSMC6 -4878
PSMC4 -4808
RPS5 -4778
PIK3CD -4759
MYH9 -4726
RPS11 -4702
MMP2 -4677
RPS19 -4661
ANK1 -4656
HSPA8 -4654
RPS28 -4652
VAV3 -4642
PSMD9 -4638
AP2M1 -4603
CSNK2A2 -4546
EZR -4464
ARPC1B -4429
HSP90AB1 -4426
RPLP1 -4391
MAPK7 -4382
EPHB4 -4379
PIK3R1 -4376
PSMB7 -4372
RPS12 -4367
PTK2 -4346
ITGAV -4312
RPL27A -4297
RPLP0 -4290
UBB -4263
CLASP2 -4246
PSMA4 -4211
RPL35A -4159
ITGB1 -4145
GAB2 -4127
MAP2K1 -4120
UTRN -4105
LYPLA2 -4095
PSMC5 -4091
CAP1 -4085
RPL30 -4081
PPP3CB -4060
RPS9 -4028
GRB7 -4006
GDNF -3969
RPL18 -3961
NCK2 -3916
CACNA1H -3915
RPL26L1 -3873
DLG1 -3865
RPS6KA1 -3857
RPS29 -3844
RPL6 -3843
UPF2 -3830
NRCAM -3815
PLXNA2 -3814
PSME3 -3813
FRS2 -3790
SHC3 -3782
PLXNB3 -3778
RBX1 -3714
ROCK1 -3594
RPL28 -3546
PABPC1 -3543
RPSA -3520
AP2A2 -3499
EFNB2 -3470
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
MYL12A -3398
RPS17 -3369
RPS24 -3352
SIAH1 -3347
SEMA7A -3299
RPS14 -3261
PIP5K1C -3229
SMARCA4 -3226
EGR2 -3207
RPS27L -3180
RPS10 -3155
ENAH -3139
SEM1 -3130
PSMA3 -3078
GRB2 -3047
LYN -3038
RPS6KA3 -3030
ABL2 -3020
RPS15A -3019
ELOB -3004
DOK6 -2987
RPL7 -2984
RPL34 -2974
PSMD8 -2928
RPS21 -2927
AP2S1 -2922
ARHGEF7 -2913
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
DSCAML1 -2830
PIK3CA -2813
RPS27A -2773
ROCK2 -2772
PSMA5 -2715
DOK4 -2697
CAP2 -2694
RPL23A -2692
RPL10A -2689
RPS6 -2681
ADAM10 -2671
RPS18 -2648
PDLIM7 -2636
RPL41 -2635
PIK3CB -2588
RPS13 -2581
PSMD13 -2577
RPL4 -2563
PSEN2 -2559
RPS23 -2467
RPL37A -2451
PRX -2432
PSMC2 -2389
AGRN -2369
PSME1 -2348
PSENEN -2327
PIK3R3 -2279
RPL39 -2270
RPL18A -2240
RPL7A -2233
ARPC2 -2209
DAG1 -2174
CDC42 -2172
NCBP1 -2151
RPS4Y1 -2120
RPL27 -2070
KRAS -2044
NTN4 -1999
PSMB3 -1915
RPL23 -1913
AP2A1 -1902
MAPK13 -1875
SDCBP -1822
RPL24 -1804
SRGAP1 -1796
RPL38 -1791
SRGAP2 -1779
RPS20 -1754
RPL26 -1747
RBM8A -1583
RRAS -1578
ARPC5 -1511
PSMC3 -1509
PRKACB -1429
RND1 -1410
PIK3R2 -1355
CDK5 -1352
YES1 -1340
RPL15 -1313
LAMC1 -1300
EFNA3 -1228
RPL3 -1165
RPS6KA2 -1149
PSMB4 -1144
RPL17 -1119
ARHGEF12 -1086
RPS8 -1071
PLXNA1 -1050
PLXNB1 -1046
HSP90AA1 -1030
RPL12 -983
MAGOH -969
SOS1 -950
RPS25 -937
SH3KBP1 -917
L1CAM -904
PSMA7 -892
PTPN11 -867
PRKAR2A -860
PSMB5 -742
RPL13 -706
MAPK8 -700
ITGA2B -688
RELN -662
NCSTN -554
RPL5 -495
GRIN1 -442
PSMD11 -432
ADGRG6 -428
KALRN -408
HDAC2 -338
SCN11A -295
WWTR1 -271
RPL22L1 -214
RPS3A -179
CDK5R1 -157
RPS27 -152
PSMA6 -126
RAC1 44
SDC2 147
ITSN1 159
CNTN2 200
SCN8A 249
MAPK11 251
RPL9 261
ANK3 303
RPL31 330
CUL2 359
RPS26 419
PSMB10 423
CREB1 474
SHTN1 547
ITGA5 587
APH1A 619
ELOC 645
RPS6KA4 731
NAB1 765
UBC 779
PTPRA 815
SLIT1 886
SHANK3 935
ARTN 973
RDX 1011
MYH11 1015
PAK1 1031
PSMB1 1054
EIF4A3 1154
LAMA1 1285
RGMB 1321
GRIN2B 1330
NRP1 1353
RPL21 1385
ACTR2 1435
NCK1 1525
DPYSL4 1531
CLASP1 1561
LIMK1 1565
GAB1 1575
EPHA10 1725
EFNA2 1735
PRKACA 1736
PSMB2 1876
LDB1 1882
USP33 1924
FYN 1937
CACNB4 1983
ABL1 2023
AP2B1 2029
COL6A3 2085
RPL22 2142
YAP1 2171
MAPK14 2269
NRAS 2310
UPF3B 2326
SPTAN1 2385
SCN1B 2398
PRKCA 2439
EVL 2467
SCN3B 2499
PLCG1 2511
MYH10 2558
RASA1 2559
ABLIM3 2675
MYL9 2704
HOXA2 2735
VAV2 2817
RPL36A 2875
MBP 2888
CACNB1 2967
VLDLR 3001
ARPC1A 3022
AKAP5 3035
RPS6KA5 3086
ALCAM 3171
RGMA 3210
COL6A2 3222
EFNB3 3419
EFNB1 3480
SCN9A 3533
DOCK1 3540
SCD5 3592
TRPC1 3602
EFNA4 3658
FARP2 3688
CACNB3 3735
LAMB1 3783
ARPC3 3797
NRTN 3870
SPTBN2 3883
RPS6KA6 3918
SRC 3962
SEMA3A 4001
NEO1 4016
DOK1 4072
PSMD12 4303
PLXNC1 4319
MSI1 4326
GFRA3 4393
AGAP2 4399
CSNK2B 4415
TIAM1 4452
PSMD4 4567
ROBO3 4691
PSMD10 4933
PSMD7 4942
EPHA1 4960
DLG4 5108
PSMD5 5116
ITGA1 5152
DLG3 5168
GPC1 5178
CD24 5327
PSMB9 5491
MYH14 5492
FES 5506
ERBB2 5534
MAGOHB 5814
PSMD14 5974
KIF4A 6056
RHOB 6064
APH1B 6168
ABLIM2 6389
LIMK2 6394
CLTCL1 6404
TEAD1 6440
SEMA4D 6479
DNM1 6505
MAPK3 6640
GJB1 6678
COL4A5 6694
CYP51A1 6741
SRGAP3 6775
NCBP2 6823
ADGRV1 6861
PFN2 6877
NGEF 7064
COL9A3 7151
FLRT3 7184
CNTNAP1 7239
PMP22 7297
SREBF2 7304
COL6A1 7322
SCN1A 7327
COL9A2 7348
HMGCR 7355
MPZ 7386



L13a-mediated translational silencing of Ceruloplasmin expression

L13a-mediated translational silencing of Ceruloplasmin expression
573
set L13a-mediated translational silencing of Ceruloplasmin expression
setSize 108
pANOVA 4.15e-13
s.dist -0.404
p.adjustANOVA 5.71e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
EIF4A1 -6995
RPL36AL -6981
EIF3A -6965
EIF4G1 -5901
EIF4B -5898
EIF3I -5279
RPL19 -5254
EIF2S1 -5190
RPS7 -5138
EIF3B -5127
UBA52 -5068
EIF4H -5055
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
EIF3G -4724
RPS11 -4702

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
EIF4A1 -6995
RPL36AL -6981
EIF3A -6965
EIF4G1 -5901
EIF4B -5898
EIF3I -5279
RPL19 -5254
EIF2S1 -5190
RPS7 -5138
EIF3B -5127
UBA52 -5068
EIF4H -5055
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
EIF3G -4724
RPS11 -4702
RPS19 -4661
RPS28 -4652
EIF3J -4539
EIF2S2 -4458
RPLP1 -4391
RPS12 -4367
EIF3M -4358
RPL27A -4297
RPLP0 -4290
RPL35A -4159
RPL30 -4081
RPS9 -4028
RPL18 -3961
RPL26L1 -3873
RPS29 -3844
RPL6 -3843
EIF3D -3740
EIF2S3 -3669
RPL28 -3546
PABPC1 -3543
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
RPS15A -3019
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
RPS27A -2773
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RPS13 -2581
RPL4 -2563
RPS23 -2467
RPL37A -2451
EIF3L -2407
RPL39 -2270
RPL18A -2240
RPL7A -2233
EIF3K -2206
RPS4Y1 -2120
RPL27 -2070
RPL23 -1913
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
RPL15 -1313
RPL3 -1165
RPL17 -1119
RPS8 -1071
RPL12 -983
RPS25 -937
EIF3F -893
RPL13 -706
RPL5 -495
EIF3C -374
EIF1AX -274
RPL22L1 -214
RPS3A -179
RPS27 -152
RPL9 261
RPL31 330
RPS26 419
EIF3H 899
RPL21 1385
RPL22 2142
EIF4E 2473
RPL36A 2875
EIF3E 3244
EIF4A2 5593



GTP hydrolysis and joining of the 60S ribosomal subunit

GTP hydrolysis and joining of the 60S ribosomal subunit
416
set GTP hydrolysis and joining of the 60S ribosomal subunit
setSize 109
pANOVA 5.93e-13
s.dist -0.399
p.adjustANOVA 6.44e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
EIF4A1 -6995
RPL36AL -6981
EIF3A -6965
EIF5 -6065
EIF4G1 -5901
EIF4B -5898
EIF3I -5279
RPL19 -5254
EIF2S1 -5190
RPS7 -5138
EIF3B -5127
UBA52 -5068
EIF4H -5055
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
EIF3G -4724

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
EIF4A1 -6995
RPL36AL -6981
EIF3A -6965
EIF5 -6065
EIF4G1 -5901
EIF4B -5898
EIF3I -5279
RPL19 -5254
EIF2S1 -5190
RPS7 -5138
EIF3B -5127
UBA52 -5068
EIF4H -5055
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
EIF3G -4724
RPS11 -4702
RPS19 -4661
RPS28 -4652
EIF3J -4539
EIF2S2 -4458
RPLP1 -4391
RPS12 -4367
EIF3M -4358
RPL27A -4297
RPLP0 -4290
RPL35A -4159
RPL30 -4081
RPS9 -4028
RPL18 -3961
RPL26L1 -3873
RPS29 -3844
RPL6 -3843
EIF3D -3740
EIF2S3 -3669
RPL28 -3546
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
RPS15A -3019
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
RPS27A -2773
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RPS13 -2581
RPL4 -2563
RPS23 -2467
RPL37A -2451
EIF3L -2407
RPL39 -2270
RPL18A -2240
RPL7A -2233
EIF3K -2206
RPS4Y1 -2120
RPL27 -2070
RPL23 -1913
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
RPL15 -1313
RPL3 -1165
RPL17 -1119
RPS8 -1071
RPL12 -983
RPS25 -937
EIF3F -893
RPL13 -706
RPL5 -495
EIF3C -374
EIF1AX -274
RPL22L1 -214
RPS3A -179
RPS27 -152
RPL9 261
RPL31 330
RPS26 419
EIF3H 899
RPL21 1385
RPL22 2142
EIF4E 2473
RPL36A 2875
EIF3E 3244
EIF5B 3318
EIF4A2 5593



Developmental Biology

Developmental Biology
268
set Developmental Biology
setSize 677
pANOVA 6e-13
s.dist -0.163
p.adjustANOVA 6.44e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
GFI1 -7110
KLF4 -7093
VASP -7075
ABLIM1 -7055
RUNX1 -7020
RPL36AL -6981
ETF1 -6952
RNPS1 -6938
TGFB1 -6934
ARHGEF28 -6925
SHC1 -6910
MAML1 -6891
MET -6878
RANBP9 -6871
EPHA2 -6857
ACTG1 -6841
GSPT1 -6825
ANK2 -6778
SEMA6A -6761
RHOC -6747

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GFI1 -7110
KLF4 -7093
VASP -7075
ABLIM1 -7055
RUNX1 -7020
RPL36AL -6981
ETF1 -6952
RNPS1 -6938
TGFB1 -6934
ARHGEF28 -6925
SHC1 -6910
MAML1 -6891
MET -6878
RANBP9 -6871
EPHA2 -6857
ACTG1 -6841
GSPT1 -6825
ANK2 -6778
SEMA6A -6761
RHOC -6747
NCOA6 -6745
PPARA -6722
SCN2A -6712
FURIN -6683
KRT18 -6682
SIAH2 -6666
PSMF1 -6663
MYL12B -6653
WASL -6543
DNM2 -6535
DPYSL2 -6519
KMT2C -6514
KRT8 -6499
EP300 -6470
ITGA10 -6466
PSME4 -6450
ARHGAP35 -6446
CLTA -6439
PSMD2 -6435
CBFB -6381
MYL6 -6380
KAZN -6374
KLF5 -6373
NAB2 -6372
GATA4 -6369
PLXNA3 -6318
ARHGAP39 -6303
PFN1 -6285
RARA -6269
KMT2D -6260
UNC5B -6252
KRT17 -6225
CLTC -6220
ITGA2 -6205
FGFR1 -6191
UPF3A -6189
KDM6A -6150
TLN1 -6146
SMAD3 -6145
PRNP -6115
ARPC4 -6094
MAP2K2 -6087
CLTB -6064
MEF2D -5995
CASC3 -5986
PSMD6 -5951
MYO9B -5920
EIF4G1 -5901
SPAG9 -5897
PCGF2 -5881
PPARGC1A -5869
CAPN1 -5850
EFNA1 -5830
PSMA2 -5801
CFL1 -5737
PSMA1 -5730
TDGF1 -5711
PLXND1 -5686
CACNA1D -5676
EZH2 -5631
PITPNA -5591
GIT1 -5582
SNW1 -5581
ROBO1 -5577
PSMC1 -5564
CTNNA1 -5558
NR5A2 -5547
HRAS -5543
MAPK12 -5538
PSMD3 -5535
GRB10 -5504
PSME2 -5481
POLR2L -5471
IRS2 -5461
MED1 -5451
SOS2 -5417
EGFR -5383
PAK4 -5359
PSMD1 -5351
TRIO -5341
NRP2 -5313
ACTR3 -5296
RHOA -5294
MYO10 -5290
MED13 -5289
POLR2F -5283
ZSWIM8 -5267
ARHGEF11 -5260
RPL19 -5254
BNIP2 -5239
HOXA4 -5235
NUMB -5224
YY1 -5214
PSPN -5177
EPHB1 -5141
RPS7 -5138
GSK3B -5101
UBA52 -5068
MAPK1 -5066
CDK4 -5064
ACTB -5057
CSNK2A1 -5040
RPL11 -5032
RPL10 -5026
RPS15 -5010
RAP1GAP -4998
FAU -4990
RPL14 -4978
PAK2 -4957
IL6R -4943
PSEN1 -4938
EPAS1 -4915
KRT23 -4907
SPTBN1 -4901
PSMB6 -4888
MED26 -4882
PSMC6 -4878
POU5F1 -4823
KRT80 -4809
PSMC4 -4808
KAT2B -4792
RPS5 -4778
PIK3CD -4759
MED15 -4756
DSP -4746
MYH9 -4726
RPS11 -4702
NR5A1 -4679
MMP2 -4677
POLR2E -4667
NCOA1 -4665
RPS19 -4661
ANK1 -4656
HSPA8 -4654
RPS28 -4652
VAV3 -4642
PSMD9 -4638
MED17 -4637
CHD9 -4634
AP2M1 -4603
CSNK2A2 -4546
EZR -4464
ARPC1B -4429
HSP90AB1 -4426
KRT19 -4417
CAPNS1 -4414
NCOR2 -4409
RPLP1 -4391
PAXIP1 -4383
MAPK7 -4382
EPHB4 -4379
PIK3R1 -4376
NCOR1 -4374
PSMB7 -4372
RPS12 -4367
PTK2 -4346
NR2F2 -4332
ITGAV -4312
RPL27A -4297
RPLP0 -4290
CDK8 -4276
UBB -4263
CLASP2 -4246
DSG2 -4228
PSMA4 -4211
MED13L -4184
RPL35A -4159
ITGB1 -4145
FOXP1 -4141
GAB2 -4127
MAP2K1 -4120
UTRN -4105
LYPLA2 -4095
PSMC5 -4091
SMAD2 -4087
CAP1 -4085
RPL30 -4081
RXRA -4073
PPP3CB -4060
RPS9 -4028
GRB7 -4006
GDNF -3969
RPL18 -3961
NOTCH1 -3923
NCK2 -3916
CACNA1H -3915
CREBBP -3888
RPL26L1 -3873
DLG1 -3865
RPS6KA1 -3857
RPS29 -3844
RPL6 -3843
UPF2 -3830
NRCAM -3815
PLXNA2 -3814
PSME3 -3813
FRS2 -3790
CACNG4 -3785
SHC3 -3782
PLXNB3 -3778
RBX1 -3714
POLR2B -3699
NR6A1 -3646
ROCK1 -3594
POLR2H -3593
CDKN1A -3580
SREBF1 -3554
RPL28 -3546
PABPC1 -3543
RPSA -3520
NFKB1 -3507
AP2A2 -3499
THRAP3 -3489
EFNB2 -3470
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
POLR2C -3425
RPL37 -3413
MYL12A -3398
RPS17 -3369
RPS24 -3352
SIAH1 -3347
MEF2A -3308
SEMA7A -3299
RBBP4 -3297
RPS14 -3261
PIP5K1C -3229
SMARCA4 -3226
KMT2A -3225
EGR2 -3207
MED18 -3198
RPS27L -3180
PPARG -3168
TCF12 -3164
RPS10 -3155
PPL -3149
ENAH -3139
SEM1 -3130
PSMA3 -3078
GRB2 -3047
LYN -3038
PKNOX1 -3036
RPS6KA3 -3030
ABL2 -3020
RPS15A -3019
ELOB -3004
DOK6 -2987
RPL7 -2984
RPL34 -2974
AKT1 -2958
JUN -2934
PSMD8 -2928
RPS21 -2927
AP2S1 -2922
ARHGEF7 -2913
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
DSCAML1 -2830
PIK3CA -2813
RPS27A -2773
ROCK2 -2772
MED27 -2745
PSMA5 -2715
DOK4 -2697
CAP2 -2694
RPL23A -2692
RPL10A -2689
RPS6 -2681
CCND3 -2677
ADAM10 -2671
RPS18 -2648
PDLIM7 -2636
RPL41 -2635
RELA -2632
TGM1 -2621
PIK3CB -2588
RPS13 -2581
TFDP1 -2579
PSMD13 -2577
RPL4 -2563
PSEN2 -2559
CCNC -2471
RPS23 -2467
RPL37A -2451
PRX -2432
PSMC2 -2389
STX1A -2377
AGRN -2369
MAP2K6 -2351
DSC2 -2349
PSME1 -2348
CDH2 -2339
PSENEN -2327
NCOA3 -2326
PIK3R3 -2279
RPL39 -2270
RPL18A -2240
RPL7A -2233
ARPC2 -2209
DAG1 -2174
CDC42 -2172
CDH15 -2166
NCBP1 -2151
RPS4Y1 -2120
RPL27 -2070
KRAS -2044
MED6 -2003
NTN4 -1999
ZNF335 -1966
AKT2 -1946
PSMB3 -1915
RPL23 -1913
AP2A1 -1902
MAPK13 -1875
SDCBP -1822
RPL24 -1804
PKP4 -1800
SRGAP1 -1796
RPL38 -1791
SRGAP2 -1779
RPS20 -1754
RPL26 -1747
ADAM11 -1647
TBL1X -1621
RBM8A -1583
RRAS -1578
FOXA2 -1563
ARPC5 -1511
PSMC3 -1509
CDK19 -1471
MED14 -1453
PRKACB -1429
RND1 -1410
TCF3 -1396
PIK3R2 -1355
CDK5 -1352
MED19 -1350
YES1 -1340
RPL15 -1313
LAMC1 -1300
GATA2 -1286
EFNA3 -1228
RPL3 -1165
RPS6KA2 -1149
PSMB4 -1144
MED10 -1134
CEBPB -1129
RPL17 -1119
ARHGEF12 -1086
RPS8 -1071
PLXNA1 -1050
PLXNB1 -1046
HSP90AA1 -1030
RPL12 -983
MAGOH -969
SOS1 -950
RPS25 -937
SH3KBP1 -917
L1CAM -904
PSMA7 -892
HNF4G -890
PTPN11 -867
PRKAR2A -860
PSMB5 -742
MED21 -723
MED24 -715
RPL13 -706
MAPK8 -700
ITGA2B -688
RELN -662
POLR2J -603
MAFA -561
NCSTN -554
RPL5 -495
PAX6 -478
GRIN1 -442
PSMD11 -432
ADGRG6 -428
KALRN -408
HDAC2 -338
SCN11A -295
WWTR1 -271
RPL22L1 -214
DSC3 -202
RPS3A -179
CDK5R1 -157
RPS27 -152
PSMA6 -126
HNF4A -121
RBBP5 -101
HDAC3 38
RAC1 44
WT1 114
SDC2 147
MED8 157
ITSN1 159
RARG 173
CNTN2 200
PKP3 204
SCN8A 249
MAPK11 251
RPL9 261
ANK3 303
RPL31 330
MED31 341
SUZ12 346
CUL2 359
PIAS2 388
RPS26 419
PSMB10 423
CREB1 474
SHTN1 547
ITGA5 587
MED16 610
APH1A 619
ELOC 645
RPS6KA4 731
CNOT6 732
NAB1 765
ACVR2A 775
UBC 779
HNF1A 783
PTPRA 815
PBX1 827
SLIT1 886
HNF1B 912
HHEX 922
ACVR2B 931
SHANK3 935
ARTN 973
RDX 1011
MYH11 1015
SLC2A4 1030
PAK1 1031
PML 1051
PSMB1 1054
EIF4A3 1154
HOXD1 1160
NANOG 1164
CACNG8 1174
KRT15 1181
ONECUT3 1186
MED25 1246
SALL1 1265
LAMA1 1285
RGMB 1321
ZNF638 1329
GRIN2B 1330
NRP1 1353
RPL21 1385
ZFPM2 1391
TBL1XR1 1404
ACTR2 1435
PKP2 1490
NCK1 1525
DPYSL4 1531
CLASP1 1561
LIMK1 1565
GAB1 1575
PAGR1 1634
EPHA10 1725
EFNA2 1735
PRKACA 1736
ADAM22 1805
STX1B 1841
PSMB2 1876
LDB1 1882
MYC 1892
USP33 1924
FYN 1937
ST14 1967
CACNB4 1983
POLR2G 2003
ABL1 2023
AP2B1 2029
COL6A3 2085
RPL22 2142
TGS1 2148
YAP1 2171
MED28 2239
MAPK14 2269
FOXO3 2282
SMARCD3 2305
NRAS 2310
JUP 2314
UPF3B 2326
EED 2369
SPTAN1 2385
SCN1B 2398
POLR2D 2418
FOXA3 2431
PRKCA 2439
EVL 2467
GATA6 2495
SCN3B 2499
PLCG1 2511
MYH10 2558
RASA1 2559
WDR5 2561
CDON 2669
ABLIM3 2675
MYL9 2704
POLR2A 2705
SPINK9 2709
HOXA2 2735
SMAD4 2742
VAV2 2817
KRT10 2866
RPL36A 2875
MBP 2888
CSTA 2890
MED4 2904
MED23 2950
CACNB1 2967
DRAP1 2970
CEBPA 3000
VLDLR 3001
ARPC1A 3022
AKAP5 3035
RPS6KA5 3086
ALCAM 3171
RGMA 3210
COL6A2 3222
CTNNB1 3272
EFNB3 3419
EFNB1 3480
MED12 3501
CARM1 3517
SCN9A 3533
DOCK1 3540
SCD5 3592
TRPC1 3602
DPPA4 3619
EFNA4 3658
FARP2 3688
CACNB3 3735
PLIN1 3775
LAMB1 3783
ARPC3 3797
NRTN 3870
SPTBN2 3883
RPS6KA6 3918
SRC 3962
SEMA3A 4001
NEO1 4016
TSC22D1 4059
DOK1 4072
CDK2 4114
STAT3 4253
PSMD12 4303
PLXNC1 4319
MSI1 4326
GFRA3 4393
AGAP2 4399
ACVR1B 4400
DKK1 4410
CSNK2B 4415
HIF3A 4444
TIAM1 4452
MEF2B 4564
PSMD4 4567
MED11 4574
DEK 4581
POLR2I 4594
PERP 4630
ROBO3 4691
ASH2L 4729
NCOA2 4780
HELZ2 4786
RBPJ 4794
MED9 4847
TFDP2 4856
PSMD10 4933
PSMD7 4942
FAM120B 4955
EPHA1 4960
CTCF 4990
GDF1 5042
KAT2A 5077
DLG4 5108
PSMD5 5116
RBBP7 5134
ITGA1 5152
DLG3 5168
GPC1 5178
CD36 5264
ONECUT1 5291
PCSK6 5326
CD24 5327
H2AFX 5356
FOXO1 5418
SRY 5473
PSMB9 5491
MYH14 5492
FES 5506
MEIS1 5510
ERBB2 5534
MED20 5621
MED30 5637
LEFTY2 5686
MED7 5750
PDX1 5812
MAGOHB 5814
POLR2K 5962
PSMD14 5974
AJUBA 6013
KIF4A 6056
RHOB 6064
MED22 6131
APH1B 6168
ABLIM2 6389
LIMK2 6394
CLTCL1 6404
MED29 6433
TEAD1 6440
SEMA4D 6479
DNM1 6505
PCK1 6525
MAPK3 6640
HOXA3 6669
GJB1 6678
COL4A5 6694
CYP51A1 6741
SRGAP3 6775
NCBP2 6823
MAML2 6847
ADGRV1 6861
CEBPD 6867
PFN2 6877
SALL4 6934
ANGPTL4 6953
EVPL 7038
NGEF 7064
E2F1 7096
SOX9 7103
COL9A3 7151
FLRT3 7184
CNTNAP1 7239
SLC2A2 7259
HES1 7265
PMP22 7297
SREBF2 7304
PKLR 7311
COL6A1 7322
SCN1A 7327
COL9A2 7348
CSF3R 7351
PRSS8 7354
HMGCR 7355
MPZ 7386



Signal Transduction

Signal Transduction
1072
set Signal Transduction
setSize 1748
pANOVA 6.08e-13
s.dist -0.106
p.adjustANOVA 6.44e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
SEL1L -7124
ATP2A2 -7119
MTMR4 -7109
SYVN1 -7108
TMED2 -7071
ATP6V0B -7064
ARRB1 -7062
PGF -7053
DERL2 -7046
RAMP1 -7037
SHB -7035
CX3CL1 -7031
RUNX1 -7020
SQSTM1 -7010
RRAGC -7009
STEAP3 -6993
GPER1 -6992
OS9 -6986
ATP6V0A1 -6979
ARHGEF2 -6977

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SEL1L -7124
ATP2A2 -7119
MTMR4 -7109
SYVN1 -7108
TMED2 -7071
ATP6V0B -7064
ARRB1 -7062
PGF -7053
DERL2 -7046
RAMP1 -7037
SHB -7035
CX3CL1 -7031
RUNX1 -7020
SQSTM1 -7010
RRAGC -7009
STEAP3 -6993
GPER1 -6992
OS9 -6986
ATP6V0A1 -6979
ARHGEF2 -6977
PEBP1 -6972
RHOQ -6969
DVL3 -6967
AMOTL2 -6961
PIK3AP1 -6957
JAG1 -6948
TGFB1 -6934
CCR6 -6932
F2RL1 -6927
BCAR1 -6926
ARHGEF28 -6925
ATP6V1D -6922
SHC1 -6910
ATP6V0D1 -6908
ARHGAP32 -6905
MAML1 -6891
CCL20 -6885
P4HB -6884
ATP6V0A2 -6880
MET -6878
RANBP9 -6871
VGF -6864
EPHA2 -6857
SFPQ -6854
DAGLA -6851
ACTG1 -6841
GOLGA3 -6836
FLNA -6833
HNRNPM -6829
BCL9L -6828
PDGFRB -6820
SEC13 -6812
ST3GAL4 -6801
TRIB3 -6798
PPP1R15A -6783
RHOC -6747
RRAGD -6743
PTPN3 -6738
HNRNPF -6735
VCP -6720
RAPGEF2 -6716
FURIN -6683
FOSL1 -6672
ACTN1 -6670
DDX5 -6665
PSMF1 -6663
NUDC -6662
EMC3 -6661
MYL12B -6653
TNFRSF10B -6645
RHOBTB3 -6640
TFRC -6637
KIF5A -6634
ATP6V0E1 -6622
AKAP13 -6600
DLC1 -6599
GNA13 -6594
RAPGEF1 -6586
PRKCZ -6584
VEGFB -6562
NF2 -6559
TCF7 -6556
RALA -6548
WASL -6543
DUSP3 -6541
ESYT1 -6539
DNM2 -6535
VRK2 -6520
CD55 -6517
ANKLE2 -6513
APP -6492
VHL -6491
TLE4 -6478
EP300 -6470
MAPKAPK2 -6461
PSME4 -6450
ARHGAP35 -6446
RXFP4 -6443
CLTA -6439
NFKBIA -6437
PSMD2 -6435
ADRA2C -6434
CAMKK1 -6422
P2RY11 -6403
PDE4D -6396
POGLUT1 -6385
CBFB -6381
MYL6 -6380
KDM3A -6378
NAB2 -6372
FNBP1 -6371
TMEM59 -6370
MIS12 -6367
HEBP1 -6361
BCL2L1 -6349
CDC42EP4 -6344
BAIAP2L1 -6338
PIP4K2C -6335
DNAJB1 -6326
ARHGAP39 -6303
ABHD12 -6295
PFN1 -6285
FNTA -6282
TAX1BP1 -6281
LRIG1 -6280
GNA12 -6278
ATP6V1E1 -6271
RARA -6269
KMT2D -6260
KDM4A -6254
LCK -6250
MAPK6 -6249
RBBP6 -6244
ATP6AP1 -6235
SMURF1 -6229
CLTC -6220
FZD9 -6213
SH3RF1 -6212
DGKZ -6208
ITGA2 -6205
PTPRK -6199
SPEN -6197
PLCB1 -6196
PRDM4 -6194
FGFR1 -6191
ABHD17A -6185
ATF2 -6175
ERLEC1 -6168
PARD3 -6165
TLN1 -6146
SMAD3 -6145
SHMT2 -6143
RDH10 -6134
BCAP31 -6129
DAB2IP -6128
BAD -6118
PTPRJ -6103
LATS2 -6101
ARPC4 -6094
FOSB -6091
ITCH -6089
ITPR3 -6088
MAP2K2 -6087
ATP6V0C -6086
ADM2 -6068
CYLD -6066
CLTB -6064
KIDINS220 -6056
MYLIP -6047
PTHLH -6042
PTBP1 -6035
STARD13 -6024
RAB9A -6014
MEF2D -5995
MFN2 -5992
DDRGK1 -5991
AKT1S1 -5990
RRAD -5988
DGKE -5985
DUSP4 -5977
SLC1A5 -5969
RASGRF2 -5955
ZDHHC7 -5954
PSMD6 -5951
CLIP1 -5947
IKBKG -5946
LETM1 -5941
CDC42BPA -5937
MAPKAP1 -5936
SPATA13 -5931
ATP6V1C2 -5929
CCT2 -5926
BCL9 -5924
MYO9B -5920
GNA11 -5916
EIF4G1 -5901
USF2 -5900
EIF4B -5898
ZRANB1 -5895
SIN3A -5884
SPP1 -5872
CCT6A -5862
CXXC5 -5859
MEMO1 -5843
HTR7 -5841
ADAM17 -5836
RTKN -5834
KIF2A -5815
RAB7A -5810
FKBP4 -5807
DIAPH1 -5806
PDE3A -5805
AGO3 -5803
PSMA2 -5801
WHAMM -5798
CXCL16 -5783
RIPK2 -5779
DYNC2H1 -5775
MAPKAPK3 -5773
AXIN2 -5745
ZNRF3 -5742
PPP2R5A -5740
CFL1 -5737
PPM1A -5736
ELK1 -5733
NET1 -5731
PSMA1 -5730
WASF1 -5712
RCC2 -5709
CBL -5708
MAF1 -5705
TOR1AIP1 -5699
MKRN1 -5695
PLXND1 -5686
SNAP23 -5681
STAT1 -5668
SOWAHC -5665
IQGAP1 -5663
NDEL1 -5652
CRK -5650
DLG5 -5644
PRKCD -5638
ARHGAP42 -5635
EZH2 -5631
MTA2 -5619
YBX1 -5615
RGL1 -5600
ECE1 -5583
GIT1 -5582
SNW1 -5581
ATP6V1B2 -5574
DUSP5 -5568
DUSP1 -5567
PSMC1 -5564
CTNNA1 -5558
RAF1 -5557
CASP10 -5555
NR5A2 -5547
HRAS -5543
SLC38A9 -5539
MAPK12 -5538
PSMD3 -5535
AGO2 -5530
RGS14 -5515
FAM13B -5513
PRKCE -5510
MADD -5505
GRB10 -5504
ZDHHC9 -5497
SH3PXD2A -5496
PIP4K2A -5495
DKK4 -5490
CDC42EP2 -5487
PSME2 -5481
SHC2 -5479
POLR2L -5471
AATF -5468
SOCS6 -5467
IRS2 -5461
MED1 -5451
NCF2 -5438
BRK1 -5431
USP2 -5430
KIF5B -5426
TMEM87A -5423
SOS2 -5417
TRIM33 -5413
SP1 -5412
PLIN3 -5406
ARF6 -5404
EGFR -5383
ARHGDIA -5377
GRIN2D -5370
STRN -5363
PAK4 -5359
CDC42BPB -5357
ATP6V1G1 -5352
PSMD1 -5351
CSNK1A1 -5349
TRIO -5341
PTPN12 -5326
IQGAP2 -5323
LAMA3 -5316
NRP2 -5313
CHN2 -5305
PDE3B -5303
STX5 -5300
RIT1 -5298
ACTR3 -5296
RHOA -5294
LAMTOR5 -5293
POLR2F -5283
DUSP10 -5271
ARHGEF11 -5260
CASP3 -5257
SMURF2 -5253
FSTL3 -5252
CASP9 -5247
ARAF -5242
NUMB -5224
RBMX -5221
PIK3C3 -5220
PSAP -5218
YY1 -5214
RAP1GDS1 -5198
FKBP1A -5189
CDC37 -5178
PSPN -5177
FOS -5174
PPP2CA -5168
COPS2 -5161
PPP1CA -5153
WWP2 -5151
KDM4C -5149
SLK -5147
PPP2R5B -5131
SAMM50 -5117
MXD4 -5116
PTENP1 -5107
GSK3B -5101
DBN1 -5099
INSR -5097
AAMP -5076
PDGFC -5072
UBA52 -5068
MAPK1 -5066
CDK4 -5064
PLEKHG2 -5061
ACTB -5057
CSNK2A1 -5040
PHLPP1 -5029
ZAP70 -5027
TSC1 -5024
TNFRSF10D -5009
TLE3 -5003
PDHX -4992
CTBP2 -4982
RRAS2 -4979
ETV4 -4971
JAK1 -4963
PAK2 -4957
CAB39 -4956
ARHGAP23 -4953
ALDH1A1 -4952
ATP6V1C1 -4946
ECT2 -4944
IL6R -4943
PSEN1 -4938
FAM135A -4927
ATF1 -4925
FRAT2 -4922
PHB -4920
EPAS1 -4915
NOS3 -4903
SPTBN1 -4901
YKT6 -4899
VAPA -4898
RGS3 -4893
PSMB6 -4888
PLTP -4883
PSMC6 -4878
PDE8A -4877
SNX3 -4858
WNT7B -4849
AREG -4847
VPS26A -4841
TRIM27 -4835
CHD4 -4830
RRAGB -4819
ARFGAP3 -4817
PSMC4 -4808
TNRC6C -4805
TJP1 -4801
KAT2B -4792
TNKS -4790
PIK3CD -4759
IGF2BP1 -4754
SH2B3 -4752
BRAF -4749
DSP -4746
PPP2R1A -4744
HMOX2 -4742
PKN1 -4731
ACBD5 -4727
MYH9 -4726
PTEN -4721
MST1 -4720
CCNT1 -4690
CDC73 -4683
MMP2 -4677
SNAI1 -4674
ZNF512B -4669
POLR2E -4667
NCOA1 -4665
KDM1B -4647
RTN4 -4643
VAV3 -4642
FAF2 -4640
PSMD9 -4638
LRP6 -4613
EEPD1 -4610
GNAI3 -4609
AP2M1 -4603
CHD8 -4588
KPNA2 -4575
ALDH3A2 -4574
B9D2 -4569
SPPL2A -4568
CSNK2A2 -4546
ROR1 -4544
MBD3 -4543
PEAK1 -4528
GPS2 -4524
PPP2CB -4523
GNB2 -4514
TGFA -4511
ARAP3 -4484
ABI1 -4478
ARHGAP5 -4477
SEH1L -4472
DAAM1 -4459
VEGFA -4456
USP34 -4441
TIAL1 -4432
ARPC1B -4429
HSP90AB1 -4426
ATP6V1H -4423
ARHGAP21 -4412
NCOR2 -4409
WNT2B -4408
HBEGF -4402
TNFRSF10A -4397
MAPK7 -4382
PIK3R1 -4376
NCOR1 -4374
PSMB7 -4372
MCHR1 -4371
CBX8 -4370
MIB2 -4356
PTK2 -4346
USP15 -4344
UBE2M -4337
ITPR1 -4321
USP9X -4318
ITGAV -4312
RACK1 -4287
PRMT1 -4281
PHC1 -4280
CDK8 -4276
MAP3K11 -4272
UBB -4263
IHH -4252
ATN1 -4249
CLASP2 -4246
TMED5 -4243
RGS12 -4241
DSG2 -4228
CYP26B1 -4218
AXIN1 -4215
TNRC6B -4212
PSMA4 -4211
HGS -4210
IQCE -4208
SH3GL1 -4200
BMI1 -4180
PPP3R1 -4176
SFN -4169
TWF1 -4167
HIF1A -4165
P2RY2 -4163
MCAM -4158
VANGL1 -4152
ITGB1 -4145
STRAP -4142
CUL1 -4129
UHRF1BP1L -4128
GAB2 -4127
PPP1R12B -4126
MAP2K1 -4120
PPID -4119
CSK -4113
GATAD2A -4108
FMNL2 -4100
PSMC5 -4091
SMAD2 -4087
WDR81 -4080
TXNL1 -4076
RXRA -4073
AHCTF1 -4070
CBX4 -4063
PPP3CB -4060
NOX3 -4056
ZW10 -4054
MAPKAPK5 -4050
ECE2 -4044
HDAC5 -4034
DAGLB -4017
FGF17 -4015
CRABP2 -4007
GRB7 -4006
NR3C1 -4005
UBE2D3 -3997
MARK3 -3996
SPINT1 -3991
EGR3 -3972
GDNF -3969
CKAP4 -3939
ARHGEF16 -3936
PHLPP2 -3934
NOTCH1 -3923
BAIAP2L2 -3920
NCK2 -3916
SPRED3 -3905
GNAI2 -3904
RPS6KB2 -3901
DYNC1LI2 -3897
TNS3 -3893
CREBBP -3888
TAB2 -3878
DUSP7 -3870
DLG1 -3865
HEY1 -3864
PGRMC2 -3863
RPS6KA1 -3857
BCL2L11 -3834
GFOD1 -3825
ARHGEF5 -3818
PSME3 -3813
MFN1 -3811
STK38 -3810
PTPN2 -3809
KLB -3807
FAM91A1 -3805
MAPRE1 -3795
FRS2 -3790
SHC3 -3782
ATP6V1A -3777
PLCG2 -3766
NUP98 -3764
RHEB -3762
FGFRL1 -3751
SOX4 -3727
TNS4 -3726
GNAZ -3724
RBX1 -3714
GPHA2 -3711
POLR2B -3699
FERMT2 -3698
LAT -3697
UHMK1 -3687
GSK3A -3684
MTOR -3683
PARD6B -3675
APOE -3670
GALR2 -3664
SKIL -3659
TGFBR2 -3644
WDR83 -3643
PPP1CB -3630
RPS6KB1 -3622
ARHGEF25 -3620
SH2B1 -3615
DYNC1H1 -3614
CPNE8 -3609
ROCK1 -3594
POLR2H -3593
RDH14 -3592
TRRAP -3581
CDKN1A -3580
UCN2 -3575
STIP1 -3571
SREBF1 -3554
JUNB -3526
YWHAH -3511
NFKB1 -3507
GPS1 -3506
EMD -3504
AP2A2 -3499
RCOR1 -3493
GRAP -3478
LMAN1 -3431
POLR2C -3425
GOLGA7 -3421
GRK3 -3418
KHDRBS3 -3395
PPP1CC -3392
DTX2 -3377
DUSP6 -3376
KLC2 -3375
WASF2 -3366
CHUK -3364
STBD1 -3361
HSPB1 -3343
STAG1 -3341
TAOK3 -3324
CHD1 -3315
MEF2A -3308
SHH -3305
RBBP4 -3297
SPOP -3272
TIAM2 -3267
ST3GAL6 -3252
ARRB2 -3248
LATS1 -3238
GNB1 -3237
PIP5K1C -3229
GALNT3 -3227
SMARCA4 -3226
KTN1 -3223
TNKS2 -3213
SAV1 -3212
EGR2 -3207
TAS1R3 -3182
PPARG -3168
TCF12 -3164
E2F4 -3153
STK11 -3146
SPHK1 -3142
SEM1 -3130
FN1 -3115
GNRH1 -3111
GTF2F1 -3103
SWAP70 -3097
SRF -3090
LEO1 -3088
ANOS1 -3087
PSMA3 -3078
CUL3 -3056
PRKAA2 -3053
GRB2 -3047
PDE4A -3039
LYN -3038
RPS6KA3 -3030
KCTD13 -3029
ARHGAP17 -3026
ABL2 -3020
RGL2 -3017
CKB -3007
VPS35 -3006
KISS1 -2999
ARHGAP26 -2989
NPW -2970
WIPF2 -2965
AKT1 -2958
JUN -2934
IKBKB -2931
XIAP -2929
PSMD8 -2928
AP2S1 -2922
ARHGEF7 -2913
ARMCX3 -2911
PELP1 -2894
RBCK1 -2891
RIPK1 -2886
AKAP12 -2868
TAOK1 -2864
SPRED2 -2862
USP8 -2820
ADCY6 -2818
PIK3CA -2813
TLE1 -2800
FGFR4 -2795
NCKAP1 -2788
DYNC1I2 -2780
ELMO1 -2779
RPS27A -2773
ROCK2 -2772
RHOG -2756
IGF1R -2746
JAK2 -2719
PSMA5 -2715
PPP3CC -2712
GPR35 -2701
RPS6 -2681
CCND3 -2677
HDAC1 -2676
ADAM10 -2671
WNT3 -2666
PDGFA -2660
SSTR2 -2650
SCRIB -2641
RELA -2632
LAMTOR3 -2631
GPR143 -2627
TGFBR1 -2620
STAG2 -2617
AXL -2605
RHOF -2600
MTX1 -2595
PIK3CB -2588
ARC -2587
TFDP1 -2579
PSMD13 -2577
SPRED1 -2574
FBXW7 -2564
PSEN2 -2559
DGKD -2554
FNTB -2551
ADM -2543
RYK -2525
RHOJ -2522
DYNC1LI1 -2519
SIRT6 -2510
BCR -2502
OTULIN -2499
GNAI1 -2495
TAX1BP3 -2489
CCNC -2471
TSC2 -2462
ALDH1A2 -2454
MAP2K5 -2441
PMF1 -2433
MSI2 -2422
PLCB3 -2412
FMNL1 -2403
FST -2393
PSMC2 -2389
TLR9 -2371
ESRP2 -2361
PSME1 -2348
OTUD3 -2342
MKNK1 -2340
PSENEN -2327
NCOA3 -2326
INHBB -2320
LRP5 -2319
ERBIN -2316
NELFB -2298
ABCA1 -2289
PIK3R3 -2279
DVL1 -2264
CFLAR -2258
CPSF7 -2243
OSBPL11 -2229
PDK3 -2228
IRAK1 -2218
ARPC2 -2209
USF1 -2194
CDC42 -2172
ARHGAP9 -2170
CCDC88C -2163
NCBP1 -2151
RAB4A -2148
PPP2R5D -2117
GPSM3 -2116
OXTR -2112
ABHD17B -2101
PRR5 -2094
FOXO4 -2077
RICTOR -2076
KRAS -2044
ARHGEF19 -2038
TP53 -2020
DLG2 -2019
DDX39B -1996
SPRY2 -1990
DGKQ -1982
DOCK8 -1981
DST -1950
AKT2 -1946
SPRY1 -1918
PSMB3 -1915
OTUD7B -1911
AP2A1 -1902
RGS10 -1881
MAPK13 -1875
XPO1 -1864
PIP5K1A -1831
APC -1818
WDR19 -1802
PKP4 -1800
SRGAP1 -1796
HNRNPA1 -1795
SRGAP2 -1779
SKI -1777
PRKAB2 -1763
DUSP16 -1750
NDE1 -1744
HECW1 -1713
PTCH1 -1712
CHN1 -1698
MMP3 -1680
NTSR1 -1675
ITGA3 -1662
ARAP2 -1642
ARAP1 -1641
NPHP4 -1636
TBL1X -1621
LGR5 -1600
DLAT -1575
PRKCH -1569
STAT6 -1541
NPB -1537
MUC13 -1524
STOM -1523
DNMBP -1516
ARPC5 -1511
RFNG -1510
PSMC3 -1509
HDAC4 -1478
WWOX -1477
EGR1 -1475
CCT7 -1465
PRKACB -1429
RND1 -1410
HDAC10 -1408
ADAP1 -1403
ARHGAP12 -1400
LFNG -1376
PLEKHG6 -1364
PIK3R2 -1355
CDK5 -1352
RANBP10 -1342
YES1 -1340
CHD3 -1321
ARHGAP18 -1308
LAMC1 -1300
PDE7A -1290
VRK3 -1278
TRA2B -1257
WDR6 -1254
CUL5 -1229
PDHA1 -1224
TULP3 -1209
ABI2 -1197
FGFR3 -1195
DOCK4 -1171
CAPZB -1169
RPS6KA2 -1149
PSMB4 -1144
CSNK1G2 -1143
RGS19 -1130
RCE1 -1124
MYO9A -1107
GATAD2B -1092
CCNK -1089
ARHGEF12 -1086
CDC42EP1 -1064
PLXNA1 -1050
PLXNB1 -1046
PRKAR1B -1038
HSP90AA1 -1030
MUC20 -1019
YWHAG -1018
GNB3 -1008
RALGAPA1 -1001
RALBP1 -992
NCKAP1L -972
MDM2 -956
SOS1 -950
MYO19 -941
LEMD3 -919
SH3KBP1 -917
ARHGEF18 -909
DVL2 -905
PSMA7 -892
SENP1 -886
YWHAZ -885
ATP6V1F -868
PTPN11 -867
PRKAR2A -860
IFT57 -852
NGFR -847
PRKCI -826
TPM4 -822
TGIF2 -798
KREMEN2 -791
WWC1 -789
PPARD -788
CDKN1B -786
WWP1 -779
LAMTOR1 -774
LTB4R -754
SHOC2 -749
PSMB5 -742
EPN1 -737
NLK -733
MAPK8 -700
VAMP3 -698
ITGA2B -688
C1QBP -682
PRKAB1 -680
LAMB3 -673
ADCY2 -667
CALM1 -655
DOCK6 -639
BAIAP2 -637
SPINT2 -632
PLEKHG5 -630
POLR2J -603
REST -593
ARHGAP28 -582
TRAF2 -577
RASGRP3 -569
NCSTN -554
PRKX -553
NDUFS3 -551
ITSN2 -546
SKP1 -544
ATP6V1E2 -534
JAG2 -516
BIRC2 -499
SOX7 -497
FGD2 -487
SMAD6 -476
CD19 -472
GABRG3 -451
GRIN1 -442
PSMD11 -432
ARHGAP40 -424
RDH13 -415
KALRN -408
ABCD3 -405
CENPO -404
LGR4 -395
SRRM1 -354
RUNX3 -342
HDAC2 -338
NUP160 -329
ADGRE5 -313
SOX6 -307
RASGEF1A -290
DUSP9 -284
ID2 -282
RASA4 -277
WWTR1 -271
B4GALT1 -262
CCL28 -252
NMB -251
ARHGAP10 -233
LAMC2 -228
SPOPL -212
ABR -211
STK3 -207
CNR2 -204
KCTD6 -178
PDE6A -172
BMPR1A -166
CDK5R1 -157
RPS27 -152
LAMTOR2 -148
CCND1 -137
PSMA6 -126
PAFAH1B1 -118
RBBP5 -101
SH3BP1 -95
LEPR -88
KDM4B -59
OFD1 -45
CTBP1 -41
TPM3 -40
PLPPR2 -29
COPS4 -28
GRK5 -6
RANBP2 -4
KSR1 -1
PRKAR1A 4
BAMBI 6
NOXO1 10
ARHGEF1 21
AKR1C3 24
HDAC3 38
ERCC6L 39
CSF2RA 43
RAC1 44
RHOH 49
PDE6G 70
KITLG 92
CDC14A 127
YWHAE 129
HDAC7 130
USP7 134
ITSN1 159
ARHGEF17 172
RARG 173
TCIRG1 180
NR1H2 193
S1PR3 194
NEDD4 196
S1PR2 215
RNF31 227
MAPK11 251
CAV2 254
RALB 270
PPP2R5E 283
RAP1A 309
PORCN 320
GTF2A1 328
STK10 333
MOB1A 340
FGF5 342
SUZ12 346
IL1RL1 347
KREMEN1 364
PRKAG2 375
PPP3CA 381
PTPRS 397
PDPK1 399
RPTOR 407
SMPD2 417
PSMB10 423
RAPGEF4 438
UCHL5 443
E2F3 444
NSMAF 451
GNAS 459
CREB1 474
PLEKHG3 484
SCFD1 485
VPS29 494
LAMB2 495
RHOT2 515
CRKL 524
MCF2L 531
YWHAQ 542
CCDC115 548
GPSM1 559
NRIP1 570
STARD8 571
NEDD8 580
CCL22 584
RAD21 601
FRK 602
APH1A 619
PKN2 620
F2 635
ATP6V1G2 690
GNB5 700
LYL1 726
CAB39L 734
MTMR1 739
APOC1 746
ATP6V0D2 747
CENPL 748
NAB1 765
ACVR2A 775
UBC 779
SMC1A 784
LAMA4 790
TEX2 793
DGKH 802
GNAQ 803
PTPRA 815
RASA2 817
RNF146 825
PBX1 827
PHC3 843
HSPE1 844
MATK 851
SGK1 865
SMPD3 874
RXRB 878
ARHGAP4 930
ACVR2B 931
ELMO2 942
ABHD6 957
TCF7L2 959
PLEKHG1 966
ARTN 973
ARHGEF4 980
CTTN 982
GPR39 994
HDAC11 1004
MYH11 1015
PAK1 1031
PIP5K1B 1047
PML 1051
PSMB1 1054
ADGRE2 1057
LTB4R2 1059
E2F5 1069
PPP1R12A 1114
SOX13 1115
TRAK2 1119
PIK3R4 1132
TBXA2R 1137
SH2B2 1149
GRK6 1151
FMNL3 1155
GABRB3 1163
BUB3 1165
LAMC3 1169
LRRC1 1170
GPR161 1180
RNF43 1197
GRK2 1205
BRAP 1211
FNBP1L 1226
OPRD1 1233
FZD3 1245
EPS15 1254
POU2F1 1266
ARHGDIG 1275
ARFGAP2 1283
LAMA1 1285
RBFOX2 1286
RAB6A 1296
MEN1 1298
RHOD 1302
ARHGAP22 1306
CGN 1314
FLOT1 1317
GRIN2B 1330
KHDRBS1 1341
MOSPD2 1344
GPR83 1350
NRP1 1353
NUP133 1362
CENPP 1371
BTRC 1386
TBL1XR1 1404
ZFYVE9 1407
RAC3 1423
ACTR2 1435
SLITRK5 1437
USP4 1449
CXCR2 1464
DISP2 1498
NCK1 1525
SMAD5 1543
CLASP1 1561
LIMK1 1565
GAB1 1575
KAT5 1580
EBAG9 1586
IRAK4 1591
TRAF6 1597
SPARC 1607
RDH16 1613
PYGO2 1616
GOPC 1629
F3 1642
NF1 1648
MIB1 1650
RGS2 1680
DGKG 1694
CDKN2B 1710
CAMK2D 1711
PRKACA 1736
DOCK9 1751
HTR1D 1778
PDHB 1808
MTA1 1810
HNRNPC 1814
TNRC6A 1824
LAMTOR4 1834
NSFL1C 1848
MLST8 1875
PSMB2 1876
FASN 1885
FADD 1889
MYC 1892
CCR4 1897
RASGRF1 1900
CCR10 1905
BCL2 1925
VWF 1933
GNB4 1936
FYN 1937
CYFIP1 1939
RHPN2 1950
GAS8 1964
IL6ST 1965
LRRC41 1992
POLR2G 2003
SGO1 2010
RASAL2 2019
PICALM 2021
ABL1 2023
AP2B1 2029
TGIF1 2034
CASR 2065
EPO 2073
YWHAB 2082
COL6A3 2085
FAM13A 2086
FGF23 2097
SYDE2 2107
FRS3 2112
BMPR2 2124
CAMK2G 2145
WDR35 2156
FLT4 2167
YAP1 2171
CYBA 2202
ID3 2220
SSTR5 2225
ITPR2 2257
AGTR1 2260
FZD8 2263
CENPN 2264
MAPK14 2269
FOXO3 2282
FAS 2303
NRAS 2310
JUP 2314
ALS2 2318
HCAR1 2353
FAM169A 2362
EED 2369
IFT122 2370
SPTAN1 2385
PDK1 2405
WNT6 2412
POLR2D 2418
PRKCA 2439
PDE4C 2441
RNF111 2443
RNF2 2454
EVL 2467
TAS1R1 2471
EIF4E 2473
SYNGAP1 2484
ALDH8A1 2489
MPP7 2491
DIAPH2 2492
CYSLTR1 2493
DYNLL1 2509
PLCG1 2511
THBS2 2512
PHIP 2538
SMC3 2546
PXN 2548
GFAP 2552
MYH10 2558
RASA1 2559
TAB3 2566
SUFU 2576
RRAGA 2609
TFF1 2618
WASF3 2619
CDK9 2631
PIP4K2B 2639
SMO 2649
MYO6 2665
CDON 2669
STMN1 2680
PPP5C 2684
F2RL3 2685
TRAF1 2688
LPAR2 2695
MYL9 2704
POLR2A 2705
FGD1 2720
NBEA 2723
SMAD4 2742
PPP2R5C 2743
CCNE1 2754
PAG1 2774
KISS1R 2780
USP21 2804
NUP43 2808
CTSD 2812
GALR1 2816
VAV2 2817
ARHGAP1 2833
CETP 2836
GABRG2 2849
IFT52 2860
RGS9 2861
HCAR2 2882
CBX6 2911
UTS2B 2923
SPPL2B 2936
ABCG8 2955
AAAS 2965
DRAP1 2970
PARP1 2974
TMOD3 2983
ICMT 2988
MOB1B 3012
ARPC1A 3022
DTX4 3048
PIN1 3074
STAM2 3080
RPS6KA5 3086
SLC4A7 3094
KLC3 3105
HNRNPH1 3111
SMAD7 3117
SHARPIN 3128
LIN7B 3131
TACC3 3154
CASP8 3157
RAB4B 3174
DHRS3 3195
SHKBP1 3221
COL6A2 3222
PLEKHG4 3233
CSNK1E 3247
HCAR3 3253
CTNNB1 3272
KIF3A 3299
PTK6 3304
STRADB 3307
PEA15 3314
ESR2 3316
DLK1 3351
PKN3 3362
STUB1 3373
LYPLA1 3378
NLN 3407
TCF7L1 3414
BUB1 3416
DBT 3444
WDR11 3445
PCSK5 3449
RANGAP1 3458
STK4 3459
EREG 3467
BIRC3 3477
EPS15L1 3478
LBR 3485
XCL1 3488
C5AR2 3489
IRS1 3502
FLRT1 3504
NSL1 3516
CARM1 3517
UBE2D1 3523
CDC14B 3537
DOCK1 3540
VAPB 3551
GIPR 3556
RAP1B 3577
GNRHR2 3579
OBSCN 3598
IFT172 3605
PTPN1 3622
CXCL8 3625
WNT11 3642
TRAK1 3646
CNKSR1 3649
FARP2 3688
NR4A1 3691
PHC2 3713
VANGL2 3723
EFHD2 3725
PTGES3 3734
ARHGAP11A 3756
MYLK 3757
PAQR3 3763
MAP3K7 3767
PLIN1 3775
NEURL1B 3778
LAMB1 3783
ARPC3 3797
DOCK7 3822
CTNNBIP1 3826
CAMKK2 3831
HDAC8 3835
PRKAG1 3836
F2R 3850
CPT1B 3852
NRTN 3870
SPTBN2 3883
TRADD 3885
KLC4 3897
SRC 3962
PYGO1 3963
TBP 3968
GPSM2 3970
FLRT2 3988
EPOR 3992
GOLGA8R 4017
BAG4 4019
FABP5 4021
ARHGEF3 4045
PLD2 4048
DEF6 4058
PCP2 4061
RING1 4067
HHAT 4068
DOK1 4072
CCL16 4092
RHOT1 4106
CDK2 4114
CCNT2 4117
GNG5 4123
GPNMB 4151
POFUT1 4155
NDUFA5 4165
DLD 4167
ZFYVE16 4169
NUP85 4178
CAMK4 4196
CENPF 4197
GGA3 4199
CASP2 4204
KDM1A 4224
ERBB3 4249
STAT3 4253
ADCY9 4287
NPFFR1 4289
NOTCH3 4292
PSMD12 4303
AGO1 4307
ULK3 4342
MAD1L1 4350
CENPU 4358
TNFAIP3 4359
WDR91 4363
CHEK1 4365
GNAL 4390
GFRA3 4393
ACVR1B 4400
GIT2 4402
VCL 4407
DKK1 4410
ZDHHC21 4413
CSNK2B 4415
TRIP10 4417
GNG7 4426
IFT140 4429
FER 4431
PTPRU 4441
THBS3 4450
TIAM1 4452
ATP2A1 4477
TTC21B 4480
ID1 4484
PTAFR 4486
DOCK5 4491
IL17RD 4497
ARHGAP29 4530
CENPA 4546
ATP6V1B1 4549
GTF2F2 4556
TERT 4560
JUND 4563
CAMK2A 4566
PSMD4 4567
ELF3 4575
RHOU 4579
FZD1 4591
POLR2I 4594
PDK4 4595
DRD5 4609
KLC1 4611
PPP2R1B 4614
MDK 4615
RALGDS 4617
KCTD3 4624
ARHGAP27 4643
ARHGEF39 4647
RBL1 4660
STAP2 4664
NR1H3 4678
ARHGAP33 4686
TPH1 4694
CENPT 4715
PDE11A 4728
ASH2L 4729
POTEE 4752
BAX 4757
PLPPR1 4765
NCOA2 4780
RBPJ 4794
PLAT 4797
TNFRSF1A 4807
ADCY1 4808
SKA1 4823
KANK1 4837
FZD5 4841
TFDP2 4856
EIF4EBP1 4858
AHCYL1 4874
DUSP8 4879
SCAI 4892
ARHGEF26 4909
PSMD10 4933
PSMD7 4942
SMAD1 4977
ANLN 4979
TLE2 5001
AMER1 5007
ARHGAP8 5008
DIAPH3 5020
TAS2R4 5037
PLK1 5045
SOCS1 5053
TYK2 5066
KAT2A 5077
ARHGEF9 5100
DLG4 5108
STAM 5109
PSMD5 5116
MRAS 5118
ADORA2B 5127
RBBP7 5134
MST1R 5156
DLG3 5168
BIRC5 5174
PRKAA1 5206
FRAT1 5212
ACKR2 5219
KIF14 5224
KIF18A 5234
UACA 5249
CENPM 5262
CCDC88A 5267
DGKK 5277
SGO2 5279
APOC2 5283
STAT5A 5288
GPR176 5289
INCENP 5290
RDH5 5315
RUVBL1 5317
PCSK6 5326
ADORA2A 5330
FKBP5 5342
CLIP3 5347
H2AFX 5356
IL1RAP 5361
CDC42SE2 5380
ARHGEF10L 5384
CEP97 5393
TRIB1 5404
FOXO1 5418
IL32 5419
TNFSF10 5424
IFT88 5432
GTF2A2 5445
OXER1 5459
SRY 5473
NCKIPSD 5477
FZD7 5487
PSMB9 5491
MYH14 5492
DZIP1 5496
NOXA1 5500
FES 5506
ERBB2 5534
CENPE 5538
ADRA1D 5547
CNOT6L 5623
EVC 5630
CDC20 5650
CENPC 5660
DLGAP5 5662
ATP6V0E2 5683
ADD3 5685
INTU 5699
DGKA 5708
ARL2 5716
RACGAP1 5789
MAGED1 5797
UCN 5800
SYDE1 5815
GMIP 5817
SH2D2A 5820
RNF20 5837
TF 5850
FARP1 5879
SERPINE1 5901
CENPQ 5907
FOXA1 5915
ST3GAL3 5918
PARD6A 5924
MYD88 5939
HDAC6 5953
ARL13B 5956
POLR2K 5962
CENPI 5963
CBY1 5965
PSMD14 5974
RHOBTB1 5975
KIF2C 5981
ZWINT 5984
NISCH 5985
THBS1 5988
TNFAIP1 5996
FLT3LG 6000
CIT 6027
DYNLL2 6044
USP13 6054
MTR 6057
RHOB 6064
NUP107 6076
ANKFY1 6079
THEM4 6080
ARHGAP11B 6085
ARHGAP44 6102
DEPDC1B 6112
SMAD9 6128
GNG4 6164
APH1B 6168
RNF41 6188
ABHD17C 6192
EFCAB7 6202
CCP110 6203
KIF7 6216
CYFIP2 6224
TJP2 6225
HINT2 6227
NOTCH2 6231
ADH1A 6237
CENPH 6241
ZWILCH 6246
PTCH2 6287
RAMP2 6288
TIA1 6310
FZD6 6312
ADCY7 6316
OPHN1 6348
RDH11 6369
FGD4 6382
LIMK2 6394
ITGB3BP 6398
MOV10 6408
MTA3 6411
MKS1 6422
UBXN11 6442
RGL3 6456
DHRS4 6459
ARHGEF40 6470
DNM1 6505
SKA2 6507
PCK1 6525
OPRL1 6531
FZD4 6534
PRC1 6550
SSTR3 6553
PTPN6 6557
RGS5 6561
TAS2R5 6569
STAT5B 6572
AGO4 6581
RHPN1 6595
ABCG5 6607
DNAL4 6609
PDE6D 6611
CKAP5 6626
LAMA5 6638
MAPK3 6640
CDCA8 6649
SCMH1 6656
STRADA 6661
KNTC1 6674
OPN3 6679
TAB1 6687
COL4A5 6694
FGG 6697
HGFAC 6708
SPDL1 6715
C5AR1 6719
FGFBP3 6730
ARHGAP19 6733
MFNG 6743
GREB1 6757
EDN1 6766
KBTBD7 6772
SRGAP3 6775
GNG10 6779
PTGDR2 6780
NOTUM 6788
PTK2B 6809
FGFR2 6811
ZNF217 6814
HPN 6820
NCBP2 6823
CDC25C 6825
PDK2 6826
RPGRIP1L 6834
OCRL 6835
KLHL12 6844
MAML2 6847
PTPN18 6851
CPD 6859
PFN2 6877
AURKB 6883
DSN1 6916
PDGFB 6920
LPAR6 6924
IQGAP3 6928
SALL4 6934
CBX2 6958
EEF2K 6964
TMPO 6967
GPAM 6968
SCD 6981
BUB1B 6992
NUF2 7008
ANKRD26 7017
SPC24 7021
CENPK 7030
FGD3 7036
F11R 7054
SEMA4F 7059
NGEF 7064
MAD2L1 7070
KNL1 7073
CPT1A 7075
MC1R 7078
AGT 7091
TUBA1B 7094
E2F1 7096
NUP37 7100
LMNB1 7101
SOX9 7103
CTNND1 7129
FLOT2 7147
COL9A3 7151
NDC80 7161
THBS4 7170
FLRT3 7184
C5 7218
FGB 7226
BEX3 7227
CDK1 7230
NEDD4L 7233
HES1 7265
RHOBTB2 7276
PLD1 7290
CDH1 7296
COL6A1 7322
TFF3 7324
JAK3 7326
ADH4 7331
FGA 7336
COL9A2 7348
C3 7357
ACTA2 7362
SOCS3 7374
IGF2 7375
PLG 7380
KNG1 7382



Cholesterol biosynthesis

Cholesterol biosynthesis
162
set Cholesterol biosynthesis
setSize 24
pANOVA 8.63e-13
s.dist 0.843
p.adjustANOVA 8.49e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
MSMO1 7385
HMGCS1 7372
SQLE 7370
IDI1 7367
HMGCR 7355
MVK 7340
DHCR7 7333
MVD 7302
FDFT1 7289
LSS 7283
ACAT2 6959
ARV1 6888
FDPS 6789
CYP51A1 6741
TM7SF2 6684
NSDHL 6245
DHCR24 5816
GGPS1 5520
SC5D 5323
EBP 5151

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MSMO1 7385
HMGCS1 7372
SQLE 7370
IDI1 7367
HMGCR 7355
MVK 7340
DHCR7 7333
MVD 7302
FDFT1 7289
LSS 7283
ACAT2 6959
ARV1 6888
FDPS 6789
CYP51A1 6741
TM7SF2 6684
NSDHL 6245
DHCR24 5816
GGPS1 5520
SC5D 5323
EBP 5151
PLPP6 4705
LBR 3485
PMVK 3336
HSD17B7 2596



Translation

Translation
1283
set Translation
setSize 270
pANOVA 9.51e-13
s.dist -0.253
p.adjustANOVA 8.73e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
SEC61A1 -7030
RPN1 -7013
SSR4 -7004
TRAM1 -6997
EIF4A1 -6995
SEC11C -6991
RPL36AL -6981
EIF3A -6965
SEC61B -6958
ETF1 -6952
SSR3 -6928
SSR1 -6907
SRPRB -6893
GSPT1 -6825
SPCS3 -6781
SSR2 -6759
DDOST -6429
SRP68 -6420
MTRF1L -6400
SRP19 -6363

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SEC61A1 -7030
RPN1 -7013
SSR4 -7004
TRAM1 -6997
EIF4A1 -6995
SEC11C -6991
RPL36AL -6981
EIF3A -6965
SEC61B -6958
ETF1 -6952
SSR3 -6928
SSR1 -6907
SRPRB -6893
GSPT1 -6825
SPCS3 -6781
SSR2 -6759
DDOST -6429
SRP68 -6420
MTRF1L -6400
SRP19 -6363
RPN2 -6193
EIF5 -6065
SRP14 -5938
SPCS2 -5930
EIF4G1 -5901
EIF4B -5898
MRPS6 -5687
SRP72 -5526
MRPS15 -5376
EIF3I -5279
RPL19 -5254
MRPL38 -5234
EIF2S1 -5190
MRPS2 -5145
RPS7 -5138
EIF3B -5127
EEF1D -5115
AURKAIP1 -5100
MRPS12 -5083
UBA52 -5068
EIF4H -5055
MRPL3 -5054
EEF2 -5049
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
MRPL47 -4976
MRPL14 -4864
EIF2B5 -4838
EEF1B2 -4836
EIF2B2 -4811
SRPRA -4802
MRPL23 -4800
RPS5 -4778
EIF3G -4724
RPS11 -4702
RPS19 -4661
RPS28 -4652
MRPL34 -4611
MRPL41 -4594
MRPL35 -4563
EIF3J -4539
MRPL32 -4532
MRPS18C -4493
MRPL51 -4467
EIF2S2 -4458
MRPL46 -4455
RPLP1 -4391
RPS12 -4367
EIF3M -4358
MRPS24 -4327
RPL27A -4297
RPLP0 -4290
MRPL33 -4189
RPL35A -4159
EEF1A1 -4138
MRPL44 -4094
RPL30 -4081
SEC61G -4052
RPS9 -4028
EEF1E1 -4013
RPL18 -3961
GADD45GIP1 -3917
MRPS22 -3909
RPL26L1 -3873
TRMT112 -3869
RPS29 -3844
RPL6 -3843
EIF3D -3740
EIF2S3 -3669
EEF1G -3612
RPL28 -3546
PABPC1 -3543
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
TUFM -3458
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
MRPS18B -3346
MRPS36 -3292
RPS14 -3261
RPS27L -3180
RPS10 -3155
SEC11A -3046
RPS15A -3019
MRPL54 -3013
MRPL37 -2997
RPL7 -2984
FARSA -2976
RPL34 -2974
MRPL36 -2957
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
GFM1 -2827
RPS27A -2773
MRRF -2721
MRPL57 -2716
MRPS34 -2704
RPL23A -2692
RPL10A -2689
RPS6 -2681
MRPS23 -2664
RPS18 -2648
RPL41 -2635
MRPL48 -2613
RPS13 -2581
GFM2 -2567
RPL4 -2563
MRPS28 -2470
RPS23 -2467
RPL37A -2451
MRPL39 -2415
EIF3L -2407
MRPS11 -2271
RPL39 -2270
RPL18A -2240
RPL7A -2233
EIF3K -2206
RPS4Y1 -2120
RPL27 -2070
MRPL22 -2025
SRP54 -1969
MRPL4 -1923
RPL23 -1913
VARS2 -1827
RPL24 -1804
RPL38 -1791
IARS2 -1767
RPS20 -1754
RPL26 -1747
EEF1A1P5 -1745
MRPS30 -1657
PPA1 -1553
MRPS35 -1461
SEC61A2 -1397
MRPL53 -1391
RPL15 -1313
RPL3 -1165
RPL17 -1119
TSFM -1098
RPS8 -1071
MRPS9 -1007
RPL12 -983
RPS25 -937
EIF3F -893
MRPL18 -882
MRPL9 -726
RPL13 -706
YARS2 -645
MRPS18A -532
SARS2 -521
RPL5 -495
MRPS10 -474
MRPL40 -473
MRPL50 -402
EIF3C -374
EIF1AX -274
RPL22L1 -214
RPS3A -179
MTIF3 -173
RPS27 -152
EIF2B1 -143
MRPL19 96
RPL9 261
RPL31 330
RPS26 419
EIF2B4 437
MRPL13 482
EEF1A2 553
MTIF2 664
MRPL20 773
MRPS14 785
MRPS5 787
MRPS17 895
EIF3H 899
DAP3 972
MRPL28 1039
CHCHD1 1058
AIMP2 1067
EARS2 1253
FARS2 1328
MRPL58 1346
RPL21 1385
MRPL15 1406
PTCD3 1514
MRPL52 1657
MRPS7 1777
AIMP1 1790
MARS2 1957
CARS2 2078
NARS2 2113
RPL22 2142
ERAL1 2351
OXA1L 2372
MRPS27 2381
PPA2 2403
SPCS1 2416
DARS2 2466
EIF4E 2473
MRPL21 2518
TARS2 2575
MRPL27 2747
RPL36A 2875
MTFMT 3156
EIF3E 3244
MRPS26 3245
FARSB 3269
EIF5B 3318
MRPL10 3731
MRPL49 4062
MRPL11 4075
WARS2 4080
MRPL12 4261
APEH 4698
MRPS33 4704
MRPL43 4791
EIF4EBP1 4858
MRPS21 4888
RARS2 5085
EIF2B3 5203
MRPL42 5341
EIF4A2 5593
SRP9 5604
HARS2 5687
AARS2 5743
MRPL55 5826
MRPL1 5865
MRPL16 5878
MRPS16 5883
MRPL17 5943
MRPL30 5960
MRPL2 6122
LARS2 6133
MRPS31 6190
MRPL24 6982
MRPS25 7089
PARS2 7123
N6AMT1 7144



Cap-dependent Translation Initiation

Cap-dependent Translation Initiation
128
set Cap-dependent Translation Initiation
setSize 116
pANOVA 1.61e-12
s.dist -0.38
p.adjustANOVA 1.3e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
EIF4A1 -6995
RPL36AL -6981
EIF3A -6965
EIF5 -6065
EIF4G1 -5901
EIF4B -5898
EIF3I -5279
RPL19 -5254
EIF2S1 -5190
RPS7 -5138
EIF3B -5127
UBA52 -5068
EIF4H -5055
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
EIF2B5 -4838
EIF2B2 -4811

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
EIF4A1 -6995
RPL36AL -6981
EIF3A -6965
EIF5 -6065
EIF4G1 -5901
EIF4B -5898
EIF3I -5279
RPL19 -5254
EIF2S1 -5190
RPS7 -5138
EIF3B -5127
UBA52 -5068
EIF4H -5055
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
EIF2B5 -4838
EIF2B2 -4811
RPS5 -4778
EIF3G -4724
RPS11 -4702
RPS19 -4661
RPS28 -4652
EIF3J -4539
EIF2S2 -4458
RPLP1 -4391
RPS12 -4367
EIF3M -4358
RPL27A -4297
RPLP0 -4290
RPL35A -4159
RPL30 -4081
RPS9 -4028
RPL18 -3961
RPL26L1 -3873
RPS29 -3844
RPL6 -3843
EIF3D -3740
EIF2S3 -3669
RPL28 -3546
PABPC1 -3543
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
RPS15A -3019
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
RPS27A -2773
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RPS13 -2581
RPL4 -2563
RPS23 -2467
RPL37A -2451
EIF3L -2407
RPL39 -2270
RPL18A -2240
RPL7A -2233
EIF3K -2206
RPS4Y1 -2120
RPL27 -2070
RPL23 -1913
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
RPL15 -1313
RPL3 -1165
RPL17 -1119
RPS8 -1071
RPL12 -983
RPS25 -937
EIF3F -893
RPL13 -706
RPL5 -495
EIF3C -374
EIF1AX -274
RPL22L1 -214
RPS3A -179
RPS27 -152
EIF2B1 -143
RPL9 261
RPL31 330
RPS26 419
EIF2B4 437
EIF3H 899
RPL21 1385
RPL22 2142
EIF4E 2473
RPL36A 2875
EIF3E 3244
EIF5B 3318
EIF4EBP1 4858
EIF2B3 5203
EIF4A2 5593



Eukaryotic Translation Initiation

Eukaryotic Translation Initiation
337
set Eukaryotic Translation Initiation
setSize 116
pANOVA 1.61e-12
s.dist -0.38
p.adjustANOVA 1.3e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
EIF4A1 -6995
RPL36AL -6981
EIF3A -6965
EIF5 -6065
EIF4G1 -5901
EIF4B -5898
EIF3I -5279
RPL19 -5254
EIF2S1 -5190
RPS7 -5138
EIF3B -5127
UBA52 -5068
EIF4H -5055
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
EIF2B5 -4838
EIF2B2 -4811

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
EIF4A1 -6995
RPL36AL -6981
EIF3A -6965
EIF5 -6065
EIF4G1 -5901
EIF4B -5898
EIF3I -5279
RPL19 -5254
EIF2S1 -5190
RPS7 -5138
EIF3B -5127
UBA52 -5068
EIF4H -5055
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
EIF2B5 -4838
EIF2B2 -4811
RPS5 -4778
EIF3G -4724
RPS11 -4702
RPS19 -4661
RPS28 -4652
EIF3J -4539
EIF2S2 -4458
RPLP1 -4391
RPS12 -4367
EIF3M -4358
RPL27A -4297
RPLP0 -4290
RPL35A -4159
RPL30 -4081
RPS9 -4028
RPL18 -3961
RPL26L1 -3873
RPS29 -3844
RPL6 -3843
EIF3D -3740
EIF2S3 -3669
RPL28 -3546
PABPC1 -3543
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
RPS15A -3019
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
RPS27A -2773
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RPS13 -2581
RPL4 -2563
RPS23 -2467
RPL37A -2451
EIF3L -2407
RPL39 -2270
RPL18A -2240
RPL7A -2233
EIF3K -2206
RPS4Y1 -2120
RPL27 -2070
RPL23 -1913
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
RPL15 -1313
RPL3 -1165
RPL17 -1119
RPS8 -1071
RPL12 -983
RPS25 -937
EIF3F -893
RPL13 -706
RPL5 -495
EIF3C -374
EIF1AX -274
RPL22L1 -214
RPS3A -179
RPS27 -152
EIF2B1 -143
RPL9 261
RPL31 330
RPS26 419
EIF2B4 437
EIF3H 899
RPL21 1385
RPL22 2142
EIF4E 2473
RPL36A 2875
EIF3E 3244
EIF5B 3318
EIF4EBP1 4858
EIF2B3 5203
EIF4A2 5593



Regulation of expression of SLITs and ROBOs

Regulation of expression of SLITs and ROBOs
978
set Regulation of expression of SLITs and ROBOs
setSize 157
pANOVA 2.15e-12
s.dist -0.325
p.adjustANOVA 1.65e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL36AL -6981
ETF1 -6952
RNPS1 -6938
GSPT1 -6825
PSMF1 -6663
PSME4 -6450
PSMD2 -6435
UPF3A -6189
CASC3 -5986
PSMD6 -5951
EIF4G1 -5901
PSMA2 -5801
PSMA1 -5730
ROBO1 -5577
PSMC1 -5564
PSMD3 -5535
PSME2 -5481
PSMD1 -5351
ZSWIM8 -5267
RPL19 -5254

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL36AL -6981
ETF1 -6952
RNPS1 -6938
GSPT1 -6825
PSMF1 -6663
PSME4 -6450
PSMD2 -6435
UPF3A -6189
CASC3 -5986
PSMD6 -5951
EIF4G1 -5901
PSMA2 -5801
PSMA1 -5730
ROBO1 -5577
PSMC1 -5564
PSMD3 -5535
PSME2 -5481
PSMD1 -5351
ZSWIM8 -5267
RPL19 -5254
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
PSMB6 -4888
PSMC6 -4878
PSMC4 -4808
RPS5 -4778
RPS11 -4702
RPS19 -4661
RPS28 -4652
PSMD9 -4638
RPLP1 -4391
PSMB7 -4372
RPS12 -4367
RPL27A -4297
RPLP0 -4290
UBB -4263
PSMA4 -4211
RPL35A -4159
PSMC5 -4091
RPL30 -4081
RPS9 -4028
RPL18 -3961
RPL26L1 -3873
RPS29 -3844
RPL6 -3843
UPF2 -3830
PSME3 -3813
RBX1 -3714
RPL28 -3546
PABPC1 -3543
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
SEM1 -3130
PSMA3 -3078
RPS15A -3019
ELOB -3004
RPL7 -2984
RPL34 -2974
PSMD8 -2928
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
RPS27A -2773
PSMA5 -2715
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RPS13 -2581
PSMD13 -2577
RPL4 -2563
RPS23 -2467
RPL37A -2451
PSMC2 -2389
PSME1 -2348
RPL39 -2270
RPL18A -2240
RPL7A -2233
DAG1 -2174
NCBP1 -2151
RPS4Y1 -2120
RPL27 -2070
PSMB3 -1915
RPL23 -1913
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
RBM8A -1583
PSMC3 -1509
RPL15 -1313
RPL3 -1165
PSMB4 -1144
RPL17 -1119
RPS8 -1071
RPL12 -983
MAGOH -969
RPS25 -937
PSMA7 -892
PSMB5 -742
RPL13 -706
RPL5 -495
PSMD11 -432
RPL22L1 -214
RPS3A -179
RPS27 -152
PSMA6 -126
RPL9 261
RPL31 330
CUL2 359
RPS26 419
PSMB10 423
ELOC 645
UBC 779
SLIT1 886
PSMB1 1054
EIF4A3 1154
RPL21 1385
PSMB2 1876
LDB1 1882
USP33 1924
RPL22 2142
UPF3B 2326
HOXA2 2735
RPL36A 2875
PSMD12 4303
MSI1 4326
PSMD4 4567
ROBO3 4691
PSMD10 4933
PSMD7 4942
PSMD5 5116
PSMB9 5491
MAGOHB 5814
PSMD14 5974
COL4A5 6694
NCBP2 6823



Signaling by ROBO receptors

Signaling by ROBO receptors
1145
set Signaling by ROBO receptors
setSize 193
pANOVA 2.58e-12
s.dist -0.293
p.adjustANOVA 1.87e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
VASP -7075
RPL36AL -6981
ETF1 -6952
RNPS1 -6938
GSPT1 -6825
PSMF1 -6663
PSME4 -6450
PSMD2 -6435
ARHGAP39 -6303
PFN1 -6285
UPF3A -6189
CASC3 -5986
PSMD6 -5951
MYO9B -5920
EIF4G1 -5901
PSMA2 -5801
PSMA1 -5730
ROBO1 -5577
PSMC1 -5564
PSMD3 -5535

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
VASP -7075
RPL36AL -6981
ETF1 -6952
RNPS1 -6938
GSPT1 -6825
PSMF1 -6663
PSME4 -6450
PSMD2 -6435
ARHGAP39 -6303
PFN1 -6285
UPF3A -6189
CASC3 -5986
PSMD6 -5951
MYO9B -5920
EIF4G1 -5901
PSMA2 -5801
PSMA1 -5730
ROBO1 -5577
PSMC1 -5564
PSMD3 -5535
PSME2 -5481
SOS2 -5417
PAK4 -5359
PSMD1 -5351
RHOA -5294
ZSWIM8 -5267
RPL19 -5254
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
PAK2 -4957
PSMB6 -4888
PSMC6 -4878
PSMC4 -4808
RPS5 -4778
RPS11 -4702
RPS19 -4661
RPS28 -4652
PSMD9 -4638
RPLP1 -4391
PSMB7 -4372
RPS12 -4367
RPL27A -4297
RPLP0 -4290
UBB -4263
CLASP2 -4246
PSMA4 -4211
RPL35A -4159
PSMC5 -4091
CAP1 -4085
RPL30 -4081
PPP3CB -4060
RPS9 -4028
RPL18 -3961
NCK2 -3916
RPL26L1 -3873
RPS29 -3844
RPL6 -3843
UPF2 -3830
PSME3 -3813
RBX1 -3714
RPL28 -3546
PABPC1 -3543
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
ENAH -3139
SEM1 -3130
PSMA3 -3078
ABL2 -3020
RPS15A -3019
ELOB -3004
RPL7 -2984
RPL34 -2974
PSMD8 -2928
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
RPS27A -2773
PSMA5 -2715
CAP2 -2694
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RPS13 -2581
PSMD13 -2577
RPL4 -2563
RPS23 -2467
RPL37A -2451
PSMC2 -2389
PSME1 -2348
RPL39 -2270
RPL18A -2240
RPL7A -2233
DAG1 -2174
CDC42 -2172
NCBP1 -2151
RPS4Y1 -2120
RPL27 -2070
PSMB3 -1915
RPL23 -1913
RPL24 -1804
SRGAP1 -1796
RPL38 -1791
SRGAP2 -1779
RPS20 -1754
RPL26 -1747
RBM8A -1583
PSMC3 -1509
PRKACB -1429
RPL15 -1313
RPL3 -1165
PSMB4 -1144
RPL17 -1119
RPS8 -1071
RPL12 -983
MAGOH -969
SOS1 -950
RPS25 -937
PSMA7 -892
PRKAR2A -860
PSMB5 -742
RPL13 -706
RPL5 -495
PSMD11 -432
RPL22L1 -214
RPS3A -179
RPS27 -152
PSMA6 -126
RAC1 44
RPL9 261
RPL31 330
CUL2 359
RPS26 419
PSMB10 423
ELOC 645
UBC 779
SLIT1 886
PAK1 1031
PSMB1 1054
EIF4A3 1154
NRP1 1353
RPL21 1385
NCK1 1525
CLASP1 1561
PRKACA 1736
PSMB2 1876
LDB1 1882
USP33 1924
ABL1 2023
RPL22 2142
UPF3B 2326
PRKCA 2439
EVL 2467
HOXA2 2735
RPL36A 2875
AKAP5 3035
SRC 3962
PSMD12 4303
MSI1 4326
PSMD4 4567
ROBO3 4691
PSMD10 4933
PSMD7 4942
PSMD5 5116
GPC1 5178
PSMB9 5491
MAGOHB 5814
PSMD14 5974
COL4A5 6694
SRGAP3 6775
NCBP2 6823
PFN2 6877
FLRT3 7184



Diseases of signal transduction by growth factor receptors and second messengers

Diseases of signal transduction by growth factor receptors and second messengers
286
set Diseases of signal transduction by growth factor receptors and second messengers
setSize 361
pANOVA 3.78e-12
s.dist -0.214
p.adjustANOVA 2.6e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
SEL1L -7124
SYVN1 -7108
ARRB1 -7062
DERL2 -7046
EIF2AK3 -7028
SQSTM1 -7010
OS9 -6986
PEBP1 -6972
PIK3AP1 -6957
JAG1 -6948
TGFB1 -6934
SHC1 -6910
MAML1 -6891
MET -6878
PDGFRB -6820
VCP -6720
PSMF1 -6663
RRBP1 -6551
EP300 -6470
PSME4 -6450

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SEL1L -7124
SYVN1 -7108
ARRB1 -7062
DERL2 -7046
EIF2AK3 -7028
SQSTM1 -7010
OS9 -6986
PEBP1 -6972
PIK3AP1 -6957
JAG1 -6948
TGFB1 -6934
SHC1 -6910
MAML1 -6891
MET -6878
PDGFRB -6820
VCP -6720
PSMF1 -6663
RRBP1 -6551
EP300 -6470
PSME4 -6450
PSMD2 -6435
BCL2L1 -6349
LCK -6250
CLTC -6220
FGFR1OP2 -6202
FGFR1 -6191
ERLEC1 -6168
TLN1 -6146
SMAD3 -6145
BAD -6118
MAP2K2 -6087
KDM7A -6055
SND1 -6000
AKT1S1 -5990
PSMD6 -5951
MAPKAP1 -5936
FIP1L1 -5876
ADAM17 -5836
PSMA2 -5801
KIAA1549 -5776
SEC31A -5766
PPP2R5A -5740
PSMA1 -5730
CBL -5708
STAT1 -5668
IQGAP1 -5663
SNW1 -5581
PSMC1 -5564
RAF1 -5557
HRAS -5543
PSMD3 -5535
DKK4 -5490
PSME2 -5481
LRRFIP1 -5477
POLR2L -5471
IRS2 -5461
QKI -5427
KIF5B -5426
PPM1B -5398
EGFR -5383
STRN -5363
PSMD1 -5351
CSNK1A1 -5349
TFG -5336
PTPN12 -5326
POLR2F -5283
DUSP10 -5271
CASP9 -5247
ARAF -5242
FKBP1A -5189
CDC37 -5178
PPP2CA -5168
PPP2R5B -5131
GSK3B -5101
UBA52 -5068
MAPK1 -5066
CTBP2 -4982
PSEN1 -4938
PHB -4920
SPTBN1 -4901
MECP2 -4891
PSMB6 -4888
TRIM24 -4887
PSMC6 -4878
AREG -4847
PSMC4 -4808
FXR1 -4803
KAT2B -4792
TNKS -4790
CPSF6 -4789
PIK3CD -4759
BRAF -4749
PPP2R1A -4744
MYH9 -4726
PTEN -4721
POLR2E -4667
PSMD9 -4638
GOLGA4 -4624
LRP6 -4613
PPP2CB -4523
TGFA -4511
NCOR2 -4409
HBEGF -4402
PIK3R1 -4376
NCOR1 -4374
PSMB7 -4372
MIB2 -4356
CDK8 -4276
MAP3K11 -4272
UBB -4263
IHH -4252
AXIN1 -4215
PSMA4 -4211
CUL1 -4129
GAB2 -4127
MAP2K1 -4120
CSK -4113
PIM1 -4092
PSMC5 -4091
SMAD2 -4087
HDAC5 -4034
FGF17 -4015
MARK3 -3996
PPFIBP1 -3970
NOTCH1 -3923
SPRED3 -3905
RPS6KB2 -3901
CREBBP -3888
DUSP7 -3870
HEY1 -3864
BCL2L11 -3834
PSME3 -3813
KLB -3807
FRS2 -3790
LMNA -3717
RBX1 -3714
POLR2B -3699
GSK3A -3684
MTOR -3683
TGFBR2 -3644
PPP1CB -3630
EEF1G -3612
POLR2H -3593
CDKN1A -3580
JUNB -3526
GOLGB1 -3498
POLR2C -3425
PPP1CC -3392
DUSP6 -3376
CHUK -3364
SHH -3305
ARRB2 -3248
TNKS2 -3213
SEM1 -3130
FN1 -3115
GTF2F1 -3103
PSMA3 -3078
BIRC6 -3068
GRB2 -3047
LYN -3038
AKT1 -2958
PSMD8 -2928
SPRED2 -2862
PIK3CA -2813
FGFR4 -2795
RPS27A -2773
RHOG -2756
JAK2 -2719
PSMA5 -2715
RPS6 -2681
HDAC1 -2676
ADAM10 -2671
PDGFA -2660
TGFBR1 -2620
PIK3CB -2588
PSMD13 -2577
SPRED1 -2574
FBXW7 -2564
PSEN2 -2559
BCR -2502
CCNC -2471
TSC2 -2462
PSMC2 -2389
PSME1 -2348
PSENEN -2327
LRP5 -2319
ERBIN -2316
PIK3R3 -2279
NCBP1 -2151
PPP2R5D -2117
PRR5 -2094
FOXO4 -2077
RICTOR -2076
KRAS -2044
NPM1 -2033
AKT2 -1946
PSMB3 -1915
APC -1818
DUSP16 -1750
CUX1 -1665
DCTN1 -1635
TBL1X -1621
ETV6 -1588
PSMC3 -1509
HDAC4 -1478
HDAC10 -1408
PIK3R2 -1355
YES1 -1340
LMO7 -1246
FGFR3 -1195
PSMB4 -1144
CEBPB -1129
HSP90AA1 -1030
TRIP11 -990
MDM2 -956
SOS1 -950
PSMA7 -892
PTPN11 -867
TPM4 -822
KREMEN2 -791
CDKN1B -786
SHOC2 -749
PSMB5 -742
ITGA2B -688
CALM1 -655
POLR2J -603
GCC2 -597
NCSTN -554
SKP1 -544
ATIC -520
JAG2 -516
CD19 -472
PSMD11 -432
HDAC2 -338
DUSP9 -284
MPRIP -266
PSMA6 -126
CTBP1 -41
TPM3 -40
RANBP2 -4
KSR1 -1
PRKAR1A 4
AP3B1 13
EML4 27
HDAC3 38
RAC1 44
KITLG 92
HDAC7 130
PPP2R5E 283
RAP1A 309
PORCN 320
FGF5 342
KREMEN1 364
PDPK1 399
PSMB10 423
CREB1 474
WDR48 543
TPR 565
APH1A 619
UBC 779
TCF7L2 959
HDAC11 1004
PSMB1 1054
RNF43 1197
BRAP 1211
TBL1XR1 1404
ZFYVE9 1407
GAB1 1575
NF1 1648
MIB1 1650
CAMK2D 1711
MLST8 1875
PSMB2 1876
MYC 1892
VWF 1933
FYN 1937
POLR2G 2003
AGK 2062
YWHAB 2082
FGF23 2097
FRS3 2112
CAMK2G 2145
FZD8 2263
FOXO3 2282
NRAS 2310
POLR2D 2418
PLCG1 2511
POLR2A 2705
SMAD4 2742
PPP2R5C 2743
ZMYM2 2755
AGGF1 3135
CLCN6 3165
CTNNB1 3272
ESR2 3316
EREG 3467
IRS1 3502
RAP1B 3577
TRAK1 3646
CNKSR1 3649
NR4A1 3691
PAPSS1 3746
NEURL1B 3778
HDAC8 3835
MYO18A 3903
SRC 3962
BAG4 4019
HHAT 4068
ERBB3 4249
STAT3 4253
PSMD12 4303
VCL 4407
DKK1 4410
ZC3HAV1 4414
GTF2F2 4556
CAMK2A 4566
PSMD4 4567
POLR2I 4594
KLC1 4611
PPP2R1B 4614
RBPJ 4794
KANK1 4837
FZD5 4841
DUSP8 4879
PSMD10 4933
PSMD7 4942
AMER1 5007
KAT2A 5077
AKAP9 5113
PSMD5 5116
MRAS 5118
STAT5A 5288
ERLIN2 5405
FOXO1 5418
ATG7 5453
PSMB9 5491
ERBB2 5534
RNF213 5584
ZC3HC1 5790
AGTRAP 5793
HDAC6 5953
POLR2K 5962
PSMD14 5974
FLT3LG 6000
APH1B 6168
FZD6 6312
FAM114A2 6340
CNTRL 6358
FZD4 6534
STAT5B 6572
WDCP 6637
MAPK3 6640
FGG 6697
FGFR2 6811
NCBP2 6823
MAML2 6847
PDGFB 6920
FGB 7226
HES1 7265
HIP1 7319
FGA 7336



Response of EIF2AK4 (GCN2) to amino acid deficiency

Response of EIF2AK4 (GCN2) to amino acid deficiency
1007
set Response of EIF2AK4 (GCN2) to amino acid deficiency
setSize 98
pANOVA 7.59e-12
s.dist -0.4
p.adjustANOVA 4.98e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
DDIT3 -7047
RPL36AL -6981
TRIB3 -6798
ATF2 -6175
CEBPG -5987
ATF4 -5664
RPL19 -5254
EIF2S1 -5190
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
RPS11 -4702
RPS19 -4661
RPS28 -4652
GCN1 -4627

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DDIT3 -7047
RPL36AL -6981
TRIB3 -6798
ATF2 -6175
CEBPG -5987
ATF4 -5664
RPL19 -5254
EIF2S1 -5190
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
RPS11 -4702
RPS19 -4661
RPS28 -4652
GCN1 -4627
EIF2S2 -4458
RPLP1 -4391
RPS12 -4367
RPL27A -4297
RPLP0 -4290
RPL35A -4159
RPL30 -4081
RPS9 -4028
RPL18 -3961
RPL26L1 -3873
RPS29 -3844
RPL6 -3843
EIF2S3 -3669
RPL28 -3546
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
RPS15A -3019
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
RPS27A -2773
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RPS13 -2581
RPL4 -2563
RPS23 -2467
RPL37A -2451
RPL39 -2270
RPL18A -2240
RPL7A -2233
RPS4Y1 -2120
RPL27 -2070
RPL23 -1913
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
EIF2AK4 -1455
RPL15 -1313
RPL3 -1165
CEBPB -1129
RPL17 -1119
RPS8 -1071
RPL12 -983
RPS25 -937
RPL13 -706
RPL5 -495
RPL22L1 -214
RPS3A -179
RPS27 -152
RPL9 261
RPL31 330
RPS26 419
RPL21 1385
RPL22 2142
ATF3 2488
RPL36A 2875
IMPACT 4432
ASNS 6208



Formation of a pool of free 40S subunits

Formation of a pool of free 40S subunits
377
set Formation of a pool of free 40S subunits
setSize 98
pANOVA 1.12e-11
s.dist -0.397
p.adjustANOVA 6.94e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL36AL -6981
EIF3A -6965
EIF3I -5279
RPL19 -5254
RPS7 -5138
EIF3B -5127
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
EIF3G -4724
RPS11 -4702
RPS19 -4661
RPS28 -4652
EIF3J -4539
RPLP1 -4391
RPS12 -4367

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL36AL -6981
EIF3A -6965
EIF3I -5279
RPL19 -5254
RPS7 -5138
EIF3B -5127
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
EIF3G -4724
RPS11 -4702
RPS19 -4661
RPS28 -4652
EIF3J -4539
RPLP1 -4391
RPS12 -4367
EIF3M -4358
RPL27A -4297
RPLP0 -4290
RPL35A -4159
RPL30 -4081
RPS9 -4028
RPL18 -3961
RPL26L1 -3873
RPS29 -3844
RPL6 -3843
EIF3D -3740
RPL28 -3546
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
RPS15A -3019
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
RPS27A -2773
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RPS13 -2581
RPL4 -2563
RPS23 -2467
RPL37A -2451
EIF3L -2407
RPL39 -2270
RPL18A -2240
RPL7A -2233
EIF3K -2206
RPS4Y1 -2120
RPL27 -2070
RPL23 -1913
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
RPL15 -1313
RPL3 -1165
RPL17 -1119
RPS8 -1071
RPL12 -983
RPS25 -937
EIF3F -893
RPL13 -706
RPL5 -495
EIF3C -374
EIF1AX -274
RPL22L1 -214
RPS3A -179
RPS27 -152
RPL9 261
RPL31 330
RPS26 419
EIF3H 899
RPL21 1385
RPL22 2142
RPL36A 2875
EIF3E 3244



Metabolism of RNA

Metabolism of RNA
618
set Metabolism of RNA
setSize 658
pANOVA 1.16e-11
s.dist -0.156
p.adjustANOVA 6.94e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
CNOT10 -7014
EIF4A1 -6995
ADAT3 -6988
SNRPA1 -6983
RPL36AL -6981
ETF1 -6952
RNPS1 -6938
DDX39A -6895
HNRNPM -6829
MPHOSPH10 -6827
GSPT1 -6825
SRSF4 -6822
ZFP36L1 -6818
ALYREF -6816
SEC13 -6812
DDX49 -6809
HNRNPF -6735
PATL1 -6707
DDX5 -6665
PSMF1 -6663

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CNOT10 -7014
EIF4A1 -6995
ADAT3 -6988
SNRPA1 -6983
RPL36AL -6981
ETF1 -6952
RNPS1 -6938
DDX39A -6895
HNRNPM -6829
MPHOSPH10 -6827
GSPT1 -6825
SRSF4 -6822
ZFP36L1 -6818
ALYREF -6816
SEC13 -6812
DDX49 -6809
HNRNPF -6735
PATL1 -6707
DDX5 -6665
PSMF1 -6663
XPOT -6616
SNRPA -6516
HNRNPA3 -6510
ZFP36 -6509
EXOSC6 -6503
RAN -6476
MAPKAPK2 -6461
PSME4 -6450
HNRNPA2B1 -6445
PSMD2 -6435
CNOT3 -6386
RRP36 -6354
POM121 -6353
DHX38 -6333
RIOK3 -6332
SNRNP48 -6317
NXF1 -6277
TNPO1 -6263
UTP14C -6243
SRRT -6216
UPF3A -6189
SYF2 -6169
PRCC -6133
SLBP -6130
UTP4 -6111
POM121C -6045
CNOT8 -6043
PTBP1 -6035
SNRPD3 -5999
CASC3 -5986
SRRM2 -5973
FYTTD1 -5952
PSMD6 -5951
PUF60 -5927
EIF4G1 -5901
EIF4B -5898
FIP1L1 -5876
TRMU -5863
GPRC5A -5847
PSMA2 -5801
UTP14A -5799
SUPT5H -5767
PNO1 -5758
NSUN2 -5750
GTF2H1 -5744
FTSJ1 -5735
PSMA1 -5730
CSNK1D -5722
USP39 -5721
PHAX -5719
PRKCD -5638
YBX1 -5615
PRPF3 -5593
CLP1 -5588
SNW1 -5581
PSMC1 -5564
PSMD3 -5535
TYW1 -5525
RTCB -5521
PSME2 -5481
SRSF1 -5478
LTV1 -5474
POLR2L -5471
CDK7 -5444
PSMD1 -5351
GNL3 -5332
POLR2F -5283
NUP205 -5275
ELAC2 -5264
RPL19 -5254
DHX37 -5250
SRSF3 -5244
RBMX -5221
NOP14 -5209
SNRNP40 -5200
PPP2CA -5168
SRSF9 -5148
RPS7 -5138
RRP1 -5133
DCP2 -5125
MTO1 -5079
UBA52 -5068
ACTB -5057
RPL11 -5032
RPL10 -5026
BUD31 -5011
RPS15 -5010
NUP188 -4991
FAU -4990
RPL14 -4978
NOP10 -4958
NOL9 -4954
IMP4 -4940
PSMB6 -4888
PSMC6 -4878
CTU1 -4818
LSM1 -4814
PSMC4 -4808
EDC4 -4795
CNOT4 -4794
SART1 -4784
RPS5 -4778
NUP88 -4777
BMS1 -4769
EXOSC5 -4766
IGF2BP1 -4754
PPP2R1A -4744
NUP50 -4733
PRPF8 -4723
PPIL1 -4712
RPS11 -4702
UPF1 -4700
POLR2E -4667
SRSF10 -4662
RPS19 -4661
HSPA8 -4654
RPS28 -4652
PSMD9 -4638
IMP3 -4633
ZCCHC6 -4631
HSD17B10 -4604
DDX20 -4581
PARN -4578
SF1 -4554
UTP18 -4476
SEH1L -4472
RNGTT -4400
RPLP1 -4391
BOP1 -4381
PSMB7 -4372
RPS12 -4367
MT-ND1 -4361
WDR33 -4359
DDX1 -4308
RPL27A -4297
SF3B5 -4294
RPLP0 -4290
TEX10 -4283
UBB -4263
NHP2 -4261
CWC27 -4256
TRMT44 -4221
PQBP1 -4220
PSMA4 -4211
WDR43 -4193
SF3A1 -4178
RPL35A -4159
CD2BP2 -4125
SF3B3 -4118
DHX9 -4112
PCF11 -4093
PSMC5 -4091
RPL30 -4081
DDX47 -4068
HNRNPL -4046
RPS9 -4028
RIOK2 -4018
NT5C3B -4014
ZRSR2 -4009
PRPF40A -4000
ADAR -3971
RPL18 -3961
DDX52 -3894
CWC22 -3881
CPSF1 -3880
RBM22 -3875
RPL26L1 -3873
TRMT112 -3869
SMG8 -3868
NOP2 -3859
RPS29 -3844
RPL6 -3843
UPF2 -3830
PSME3 -3813
CHERP -3803
NOL12 -3773
NOB1 -3772
NUP98 -3764
LSM7 -3745
DDX23 -3721
THOC5 -3719
HNRNPU -3716
POLR2B -3699
PCBP1 -3633
ISG20L2 -3623
EBNA1BP2 -3613
POLR2H -3593
RPL28 -3546
PABPC1 -3543
RPSA -3520
PES1 -3505
SNRNP70 -3471
RPL8 -3467
RPS4X -3464
RPS2 -3462
EXOSC3 -3453
RPL29 -3450
RPL32 -3448
RPL36 -3432
XRN2 -3427
POLR2C -3425
SMN1 -3422
RPL37 -3413
RPS17 -3369
RPS24 -3352
HSPB1 -3343
XRN1 -3316
SF3A2 -3293
CWC25 -3271
RPS14 -3261
PAPOLA -3183
RPS27L -3180
SNRPD2 -3171
RPS10 -3155
EDC3 -3136
C2orf49 -3132
SEM1 -3130
SARNP -3109
GTF2F1 -3103
POP1 -3098
RBM17 -3092
CNOT7 -3082
PSMA3 -3078
EFTUD2 -3071
SF3A3 -3033
RPS15A -3019
GAR1 -3015
U2AF1 -2991
RPL7 -2984
RPL34 -2974
AKT1 -2958
SF3B4 -2942
PSMD8 -2928
RPS21 -2927
RPS16 -2898
PELP1 -2894
TRMT6 -2889
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
ELAVL1 -2841
UTP20 -2811
HNRNPK -2808
SMG1 -2778
ISY1 -2774
RPS27A -2773
CRNKL1 -2736
SMG7 -2718
PSMA5 -2715
FCF1 -2713
ZMAT5 -2710
TXNL4A -2705
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
WTAP -2646
BYSL -2637
RPL41 -2635
DHX16 -2633
RRP9 -2591
RPS13 -2581
PSMD13 -2577
RPL4 -2563
CDC5L -2511
UTP15 -2509
CTU2 -2497
ERI1 -2490
RPS23 -2467
RPL37A -2451
CNOT1 -2405
PSMC2 -2389
ZBTB8OS -2366
PSME1 -2348
IGF2BP2 -2324
RPL39 -2270
CPSF7 -2243
RPL18A -2240
RPL7A -2233
NIP7 -2165
NCBP1 -2151
CDC40 -2131
RPS4Y1 -2120
WBP4 -2099
NXT1 -2092
RPL27 -2070
AQR -2059
GEMIN5 -2043
PABPN1 -2037
ERCC3 -2013
PWP2 -2005
DDX39B -1996
NUP214 -1926
PSMB3 -1915
RPL23 -1913
SNRNP200 -1880
XPO1 -1864
NCL -1840
UTP6 -1836
THOC2 -1832
RPL24 -1804
HNRNPA1 -1795
RPL38 -1791
PRPF38A -1785
DHX15 -1757
LSM10 -1755
RPS20 -1754
POP7 -1753
RPL26 -1747
PLRG1 -1743
SRSF11 -1739
SF3B2 -1718
SNRPB -1707
WBP11 -1682
MT-ND2 -1660
RBM8A -1583
DIS3 -1573
NOC4L -1552
FBL -1548
PSMC3 -1509
NDC1 -1490
SENP3 -1399
SNUPN -1386
CWC15 -1362
UTP11 -1337
HEATR1 -1324
SMG6 -1323
RPL15 -1313
PDCD7 -1301
TRA2B -1257
DKC1 -1249
TFIP11 -1238
PRMT5 -1166
RPL3 -1165
WDR4 -1153
NOP56 -1145
PSMB4 -1144
RPL17 -1119
PAN3 -1113
RPS8 -1071
HNRNPUL1 -1055
TNFSF13 -1035
KHSRP -994
U2AF2 -987
RPL12 -983
SMNDC1 -978
MAGOH -969
DDX46 -967
RCL1 -942
RPS25 -937
PSMA7 -892
YWHAZ -885
BCAS2 -879
TSR1 -851
TBL3 -794
MRM2 -777
PSMB5 -742
PHF5A -729
RPL13 -706
TP53RK -693
SRSF2 -660
ZCCHC11 -659
SMG5 -654
TRMT61A -644
POLR2J -603
ERCC2 -583
TRMT10A -514
RPL5 -495
TSR3 -466
PSMD11 -432
GTF2H4 -406
OSGEP -368
TRMT1 -362
SRRM1 -354
TYW5 -351
SF3B1 -343
EXOSC10 -341
NUP160 -329
NUP62 -299
THUMPD1 -270
DDX21 -256
PPIH -247
RPL22L1 -214
MNAT1 -205
RPS3A -179
RPS27 -152
SNU13 -129
PSMA6 -126
TYW3 -105
SNRPG -99
SYMPK -77
DDX6 -74
POP4 -42
RANBP2 -4
IGF2BP3 36
DCP1A 40
CNOT2 52
TSEN54 102
TRIT1 156
SNRNP25 217
THOC1 221
MAPK11 251
RPL9 261
SLU7 281
RPL31 330
PAIP1 377
ZC3H11A 394
RPS26 419
PSMB10 423
WDR61 452
TSEN34 469
EXOSC8 472
ADAT1 478
TFB1M 518
TPR 565
SNRPB2 572
SNRPN 623
SNRPC 686
MT-CO2 716
CNOT6 732
RBM28 771
UBC 779
KRR1 924
GEMIN8 928
APOBEC3B 954
PCBP2 974
MRM1 1041
PPIL6 1052
PSMB1 1054
METTL1 1104
URM1 1139
EIF4A3 1154
CSTF3 1177
CDKAL1 1232
SUGP1 1250
RPP14 1309
PPIE 1333
NUP133 1362
RPL21 1385
POLDIP3 1421
RPP30 1439
HNRNPR 1444
GCFC2 1481
ADARB1 1506
CSTF2 1521
THOC7 1544
WDR77 1552
RPP38 1564
CPSF4 1570
MT-ND4L 1652
LSM2 1691
RPP40 1770
NSUN6 1776
HNRNPC 1814
HSPA1A 1835
THG1L 1859
PSMB2 1876
MYC 1892
ZNF473 1958
NOL6 1999
POLR2G 2003
RRP7A 2006
TNKS1BP1 2031
HBS1L 2038
PRPF31 2039
SNRNP27 2043
FTSJ3 2052
YWHAB 2082
PUS7 2099
SET 2106
WDR18 2127
RPL22 2142
TGS1 2148
DNAJC8 2214
NUDT21 2243
MAPK14 2269
PRPF4 2278
THOC3 2285
UPF3B 2326
SNRPF 2328
TPRKB 2341
U2AF1L4 2349
POP5 2364
NUP58 2380
DIMT1 2382
POLR2D 2418
PRKCA 2439
EIF4E 2473
THADA 2501
GLE1 2507
PPIL4 2522
TRMT12 2539
CSTF1 2549
HNRNPH2 2555
U2SURP 2650
SRSF7 2693
POLR2A 2705
RIOK1 2711
NUP153 2712
PRPF19 2734
MRM3 2765
NUP43 2808
RPL36A 2875
TRMT13 2920
CCAR1 2925
LAGE3 2937
AAAS 2965
MT-ND6 3010
SNRPE 3034
THOC6 3050
CHTOP 3093
HNRNPD 3107
HNRNPH1 3111
MT-ND4 3146
TSEN2 3158
TTC37 3159
EXOSC4 3220
CSNK1E 3247
EXOSC9 3293
NUP54 3310
PDCD11 3334
MT-ND5 3335
NAT10 3342
GTPBP3 3375
CTNNBL1 3386
C1D 3482
EXOSC1 3486
MT-ND3 3491
WDR75 3573
PPWD1 3615
DCP1B 3617
PUS1 3715
TRNT1 3774
EXOSC2 3779
WDR12 3814
TRMT61B 3833
DUS2 3842
CNOT11 3855
GPKOW 3887
PRPF6 3945
RNPC3 3974
SMG9 3998
NSUN4 4005
NOL11 4020
XAB2 4040
NUP85 4178
PUS3 4248
GEMIN4 4278
UTP3 4280
PSMD12 4303
GTF2H5 4373
RAE1 4394
RNMT 4440
QTRT2 4536
GTF2F2 4556
PSMD4 4567
METTL14 4585
POLR2I 4594
SKIV2L 4599
DCAF13 4652
WDR46 4709
ZCRB1 4731
NUP155 4796
METTL3 4870
ALKBH8 4880
LCMT2 4904
PSMD10 4933
PSMD7 4942
TRMT10C 4994
TRDMT1 4998
GEMIN7 5050
PSMD5 5116
LSM3 5148
PPIL3 5149
QTRT1 5195
EXOSC7 5196
LSM6 5218
LSM5 5261
GTF2H2 5321
LSM8 5399
GEMIN6 5443
HNRNPA0 5448
SF3B6 5469
PSMB9 5491
DCPS 5495
RBM5 5541
CCNH 5556
EIF4A2 5593
PNRC2 5595
NOP58 5612
MPHOSPH6 5619
CNOT6L 5623
PPP2R2A 5688
TRMT11 5691
WDR3 5692
DDX42 5700
WDR36 5735
FAM98B 5786
MAGOHB 5814
NUP93 5831
LSM11 5855
SNRPD1 5905
POLR2K 5962
PSMD14 5974
NUP35 5982
GTF2H3 6024
NUP107 6076
MT-ATP6 6186
ADAT2 6214
MTERF4 6222
CPSF3 6257
SRSF5 6261
A1CF 6295
SRSF6 6395
CPSF2 6432
TSEN15 6489
MT-CO1 6493
CLNS1A 6527
MT-ATP8 6710
GEMIN2 6729
ENPP2 6800
NUP210 6802
NCBP2 6823
TRMT5 6848
CSTF2T 6871
LSM4 6899
LAS1L 7022
NUP37 7100
SNRNP35 7126
PAN2 7162
APOBEC3C 7172
MT-CYB 7213
FUS 7280
ANP32A 7288
MT-CO3 7316
EMG1 7347
IGF2 7375



Eukaryotic Translation Elongation

Eukaryotic Translation Elongation
336
set Eukaryotic Translation Elongation
setSize 91
pANOVA 2.06e-11
s.dist -0.407
p.adjustANOVA 1.18e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL36AL -6981
RPL19 -5254
RPS7 -5138
EEF1D -5115
UBA52 -5068
EEF2 -5049
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
EEF1B2 -4836
RPS5 -4778
RPS11 -4702
RPS19 -4661
RPS28 -4652
RPLP1 -4391
RPS12 -4367
RPL27A -4297
RPLP0 -4290

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL36AL -6981
RPL19 -5254
RPS7 -5138
EEF1D -5115
UBA52 -5068
EEF2 -5049
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
EEF1B2 -4836
RPS5 -4778
RPS11 -4702
RPS19 -4661
RPS28 -4652
RPLP1 -4391
RPS12 -4367
RPL27A -4297
RPLP0 -4290
RPL35A -4159
EEF1A1 -4138
RPL30 -4081
RPS9 -4028
RPL18 -3961
RPL26L1 -3873
RPS29 -3844
RPL6 -3843
EEF1G -3612
RPL28 -3546
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
RPS15A -3019
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
RPS27A -2773
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RPS13 -2581
RPL4 -2563
RPS23 -2467
RPL37A -2451
RPL39 -2270
RPL18A -2240
RPL7A -2233
RPS4Y1 -2120
RPL27 -2070
RPL23 -1913
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
EEF1A1P5 -1745
RPL15 -1313
RPL3 -1165
RPL17 -1119
RPS8 -1071
RPL12 -983
RPS25 -937
RPL13 -706
RPL5 -495
RPL22L1 -214
RPS3A -179
RPS27 -152
RPL9 261
RPL31 330
RPS26 419
EEF1A2 553
RPL21 1385
RPL22 2142
RPL36A 2875



Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
722
set Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
setSize 91
pANOVA 2.32e-11
s.dist -0.406
p.adjustANOVA 1.27e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL36AL -6981
ETF1 -6952
GSPT1 -6825
EIF4G1 -5901
RPL19 -5254
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
RPS11 -4702
UPF1 -4700
RPS19 -4661
RPS28 -4652
RPLP1 -4391
RPS12 -4367
RPL27A -4297

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL36AL -6981
ETF1 -6952
GSPT1 -6825
EIF4G1 -5901
RPL19 -5254
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
RPS11 -4702
UPF1 -4700
RPS19 -4661
RPS28 -4652
RPLP1 -4391
RPS12 -4367
RPL27A -4297
RPLP0 -4290
RPL35A -4159
RPL30 -4081
RPS9 -4028
RPL18 -3961
RPL26L1 -3873
RPS29 -3844
RPL6 -3843
RPL28 -3546
PABPC1 -3543
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
RPS15A -3019
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
RPS27A -2773
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RPS13 -2581
RPL4 -2563
RPS23 -2467
RPL37A -2451
RPL39 -2270
RPL18A -2240
RPL7A -2233
NCBP1 -2151
RPS4Y1 -2120
RPL27 -2070
RPL23 -1913
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
RPL15 -1313
RPL3 -1165
RPL17 -1119
RPS8 -1071
RPL12 -983
RPS25 -937
RPL13 -706
RPL5 -495
RPL22L1 -214
RPS3A -179
RPS27 -152
RPL9 261
RPL31 330
RPS26 419
RPL21 1385
RPL22 2142
RPL36A 2875
NCBP2 6823



Disease

Disease
271
set Disease
setSize 1247
pANOVA 2.4e-11
s.dist -0.114
p.adjustANOVA 1.27e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
CALR -7142
DNAJC3 -7131
SLC2A1 -7130
SLC3A2 -7128
SEL1L -7124
SYVN1 -7108
CANX -7092
ANTXR2 -7077
SLC17A5 -7072
ARRB1 -7062
GFPT1 -7051
DERL2 -7046
MAGT1 -7045
MAP1LC3B -7040
RAMP1 -7037
EIF2AK3 -7028
RPN1 -7013
SLC33A1 -7011
SQSTM1 -7010
OS9 -6986

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CALR -7142
DNAJC3 -7131
SLC2A1 -7130
SLC3A2 -7128
SEL1L -7124
SYVN1 -7108
CANX -7092
ANTXR2 -7077
SLC17A5 -7072
ARRB1 -7062
GFPT1 -7051
DERL2 -7046
MAGT1 -7045
MAP1LC3B -7040
RAMP1 -7037
EIF2AK3 -7028
RPN1 -7013
SLC33A1 -7011
SQSTM1 -7010
OS9 -6986
RPL36AL -6981
PEBP1 -6972
DVL3 -6967
PIK3AP1 -6957
CTSL -6951
JAG1 -6948
ATP1B3 -6941
ARSB -6939
TGFB1 -6934
SHC1 -6910
GCLC -6903
MAML1 -6891
MET -6878
SFPQ -6854
ACTG1 -6841
PDGFRB -6820
GNS -6813
SEC13 -6812
TXNRD1 -6806
ST3GAL4 -6801
ABCB4 -6800
STT3A -6796
POMT2 -6788
ATP1A1 -6777
NEU1 -6752
ST6GALNAC4 -6726
VCP -6720
KPNA1 -6701
FURIN -6683
PRDX1 -6673
SLC35C1 -6667
DDX5 -6665
PSMF1 -6663
RNF5 -6629
ATP1B1 -6624
PCCA -6623
ABCC2 -6611
SLC6A2 -6609
ALG3 -6601
HK1 -6574
CHMP4C -6557
ALG2 -6554
RRBP1 -6551
WASL -6543
APP -6492
VHL -6491
KEAP1 -6482
BRD4 -6479
RAN -6476
EP300 -6470
HEXB -6455
PSME4 -6450
CLTA -6439
NFKBIA -6437
PSMD2 -6435
DDOST -6429
DERL1 -6423
TCEA1 -6409
SPON2 -6404
P2RY11 -6403
MGAT1 -6401
NUS1 -6395
KPNB1 -6379
IPO5 -6366
RNF185 -6359
THSD4 -6356
POM121 -6353
BCL2L1 -6349
GALNS -6314
BRMS1 -6309
NT5E -6296
UVRAG -6290
CTSA -6288
FNTA -6282
MGAT4B -6279
LCK -6250
ABCD1 -6246
DAD1 -6240
SLC12A6 -6223
CLTC -6220
FGFR1OP2 -6202
LMBRD1 -6198
RPN2 -6193
FGFR1 -6191
ERLEC1 -6168
TLN1 -6146
SMAD3 -6145
BAD -6118
TAF4 -6108
ARPC4 -6094
ITPR3 -6088
MAP2K2 -6087
ALG12 -6081
ADM2 -6068
KDM7A -6055
DPAGT1 -6046
POM121C -6045
PTHLH -6042
ARF1 -6021
SND1 -6000
AKT1S1 -5990
ALG11 -5957
PSMD6 -5951
IKBKG -5946
MAPKAP1 -5936
PRKCSH -5934
MYO9B -5920
ST3GAL1 -5905
SIN3A -5884
FIP1L1 -5876
FXYD2 -5865
MGAT5 -5854
CAPN1 -5850
HTR7 -5841
ADAM17 -5836
GTF2E2 -5813
RAB7A -5810
FKBP4 -5807
PSMA2 -5801
KIAA1549 -5776
SUPT5H -5767
SEC31A -5766
GTF2H1 -5744
PPP2R5A -5740
ELK1 -5733
PSMA1 -5730
CYP27B1 -5723
WASF1 -5712
CBL -5708
GTF2B -5704
CBLL1 -5694
CHMP1A -5693
STAT1 -5668
IQGAP1 -5663
CRK -5650
VCAN -5649
EZH2 -5631
MTA2 -5619
SNW1 -5581
MCCC1 -5566
PSMC1 -5564
RAF1 -5557
TALDO1 -5554
HRAS -5543
PSMD3 -5535
EDEM2 -5520
DKK4 -5490
ISG15 -5488
PSME2 -5481
LRRFIP1 -5477
POLR2L -5471
IDH1 -5470
IRS2 -5461
CDK7 -5444
BRK1 -5431
QKI -5427
KIF5B -5426
B3GLCT -5422
RAB5A -5408
PPM1B -5398
EGFR -5383
PDCD6IP -5380
STRN -5363
PSMD1 -5351
CSNK1A1 -5349
TFG -5336
THSD1 -5333
PTPN12 -5326
GOLGA2 -5310
ACTR3 -5296
PC -5292
MYO10 -5290
NELFA -5284
POLR2F -5283
TAF13 -5280
NUP205 -5275
DUSP10 -5271
RPL19 -5254
CASP9 -5247
ARAF -5242
SAP30 -5230
HMGA1 -5226
PIK3C3 -5220
FKBP1A -5189
PMM2 -5187
CDC37 -5178
TBK1 -5169
PPP2CA -5168
RPS7 -5138
FUT8 -5134
PPP2R5B -5131
GSK3B -5101
VAMP2 -5088
SLC9A6 -5075
UBA52 -5068
MAPK1 -5066
CDK4 -5064
ACTB -5057
LARGE1 -5056
EEF2 -5049
RPL11 -5032
RPL10 -5026
CHMP4B -5021
MGAT4A -5018
RPS15 -5010
PLK2 -5005
NUP188 -4991
FAU -4990
CTBP2 -4982
RPL14 -4978
JAK1 -4963
PAK2 -4957
ANAPC15 -4945
IL6R -4943
PSEN1 -4938
PHB -4920
SPTBN1 -4901
BSG -4895
MECP2 -4891
PSMB6 -4888
TRIM24 -4887
PSMC6 -4878
B3GALT6 -4868
ENO1 -4866
AREG -4847
TRIM27 -4835
CHD4 -4830
PGK1 -4810
PSMC4 -4808
FXR1 -4803
KAT2B -4792
TNKS -4790
CPSF6 -4789
RPS5 -4778
NUP88 -4777
IDS -4768
PIK3CD -4759
BRAF -4749
GRSF1 -4747
PPP2R1A -4744
NUP50 -4733
MYH9 -4726
PTEN -4721
RPS11 -4702
VPS37B -4696
CCNT1 -4690
POLR2E -4667
RPS19 -4661
RPS28 -4652
VAV3 -4642
PSMD9 -4638
GOLGA4 -4624
VPS37C -4620
LRP6 -4613
GNAI3 -4609
AP2M1 -4603
PGM1 -4600
KPNA2 -4575
MBD3 -4543
SSRP1 -4525
GPS2 -4524
PPP2CB -4523
ST3GAL2 -4518
GNB2 -4514
TGFA -4511
MAP2K4 -4505
TAF4B -4483
ABI1 -4478
SEH1L -4472
CTDP1 -4461
VEGFA -4456
PPIA -4443
ARPC1B -4429
HSP90AB1 -4426
ATP6V1H -4423
CAPNS1 -4414
SLC34A3 -4411
NCOR2 -4409
HBEGF -4402
RNGTT -4400
MAP2K7 -4399
NAGLU -4398
RPLP1 -4391
PIK3R1 -4376
NCOR1 -4374
PSMB7 -4372
RPS12 -4367
KPNA3 -4357
MIB2 -4356
ALG1 -4352
PTK2 -4346
CHSY1 -4336
HEXA -4335
ITPR1 -4321
RPL27A -4297
RPLP0 -4290
PRMT1 -4281
CDK8 -4276
MAP3K11 -4272
UBB -4263
IHH -4252
CYP26B1 -4218
AXIN1 -4215
PSMA4 -4211
HGS -4210
BTD -4207
AP1S2 -4204
SH3GL1 -4200
VPS37A -4187
XRCC5 -4164
RPL35A -4159
ITGB1 -4145
CUL1 -4129
GAB2 -4127
MAP2K1 -4120
CSK -4113
GATAD2A -4108
PIM1 -4092
PSMC5 -4091
SMAD2 -4087
RPL30 -4081
RAD50 -4078
HDAC5 -4034
RPS9 -4028
GGCX -4023
FGF17 -4015
GGT5 -4012
NR3C1 -4005
SLC25A5 -4001
MARK3 -3996
PPFIBP1 -3970
RPL18 -3961
GBE1 -3927
TTR -3924
NOTCH1 -3923
POMT1 -3914
SPRED3 -3905
GNAI2 -3904
RPS6KB2 -3901
DYNC1LI2 -3897
CREBBP -3888
SAP30L -3887
RPL26L1 -3873
DUSP7 -3870
HEY1 -3864
RPS29 -3844
RPL6 -3843
PARP16 -3842
CCND2 -3838
BCL2L11 -3834
PSME3 -3813
KLB -3807
FRS2 -3790
CYP27A1 -3786
CAPN2 -3774
PLCG2 -3766
NELFCD -3765
NUP98 -3764
SLC25A6 -3733
GNAZ -3724
LMNA -3717
RBX1 -3714
GPHA2 -3711
POLR2B -3699
ATP1B2 -3692
B4GAT1 -3691
GSK3A -3684
MTOR -3683
CD320 -3680
CD9 -3660
TGFBR2 -3644
PPP1CB -3630
MVB12B -3629
DYNC1H1 -3614
EEF1G -3612
TXN -3611
ROCK1 -3594
POLR2H -3593
CDKN1A -3580
MAN1B1 -3561
RPL28 -3546
JUNB -3526
DCXR -3525
RPSA -3520
NFKB1 -3507
MYO5A -3500
AP2A2 -3499
GOLGB1 -3498
RCOR1 -3493
ADAMTSL2 -3475
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
POLR2C -3425
RPL37 -3413
PAH -3408
PPP1CC -3392
RBP1 -3386
DUSP6 -3376
RPS17 -3369
WASF2 -3366
CHUK -3364
RPS24 -3352
SAP18 -3349
MAP2K3 -3342
MGAT2 -3327
SHH -3305
RBBP4 -3297
MAOA -3288
RPS14 -3261
ARRB2 -3248
GNB1 -3237
GALNT3 -3227
SLC11A2 -3217
TNKS2 -3213
B3GAT3 -3209
ALG14 -3206
SLC25A4 -3203
HMG20B -3184
RPS27L -3180
DPEP1 -3163
RPS10 -3155
SEM1 -3130
FN1 -3115
GTF2F1 -3103
TRIM28 -3099
RHBDF2 -3089
PSMA3 -3078
BIRC6 -3068
CUL3 -3056
GRB2 -3047
LYN -3038
RPS15A -3019
ELOB -3004
RPL7 -2984
RPL34 -2974
WIPF2 -2965
TAF5 -2960
AKT1 -2958
C1GALT1C1 -2939
JUN -2934
IKBKB -2931
PSMD8 -2928
RPS21 -2927
AP2S1 -2922
BECN1 -2900
RPS16 -2898
RIPK1 -2886
RPS3 -2880
TPST2 -2873
RPL13A -2872
RPLP2 -2863
SPRED2 -2862
RPL35 -2849
FXYD1 -2847
ELOA -2831
SUPT4H1 -2826
ADCY6 -2818
PIK3CA -2813
HNRNPK -2808
FGFR4 -2795
NCKAP1 -2788
DYNC1I2 -2780
ELMO1 -2779
RPS27A -2773
ROCK2 -2772
RHOG -2756
SLC35A2 -2730
JAK2 -2719
PSMA5 -2715
RPL23A -2692
RPL10A -2689
RPS6 -2681
CCND3 -2677
HDAC1 -2676
ADAM10 -2671
PDGFA -2660
RPS18 -2648
RPL41 -2635
RELA -2632
TGFBR1 -2620
SLC20A2 -2599
PIK3CB -2588
RPS13 -2581
TFDP1 -2579
PSMD13 -2577
SPRED1 -2574
FBXW7 -2564
RPL4 -2563
PSEN2 -2559
FNTB -2551
ADM -2543
B2M -2523
DYNC1LI1 -2519
BCR -2502
GNAI1 -2495
ABCB6 -2491
CCNC -2471
RPS23 -2467
TSC2 -2462
RPL37A -2451
ADAMTS17 -2445
PSMC2 -2389
TOP3A -2378
STX1A -2377
TLR9 -2371
AGRN -2369
MCCC2 -2365
MAP2K6 -2351
PSME1 -2348
PSENEN -2327
LRP5 -2319
ERBIN -2316
IFNAR2 -2313
NELFB -2298
TPMT -2290
ABCA1 -2289
SUDS3 -2287
PIK3R3 -2279
MOGS -2275
RPL39 -2270
DVL1 -2264
RPL18A -2240
RPL7A -2233
ARPC2 -2209
DAG1 -2174
CDC42 -2172
RCC1 -2159
NCBP1 -2151
SDC4 -2147
EXT1 -2144
TSG101 -2130
TPST1 -2126
RPS4Y1 -2120
PPP2R5D -2117
DPM2 -2111
NFE2L2 -2108
PRR5 -2094
NMT1 -2085
FOXO4 -2077
RICTOR -2076
RPL27 -2070
SLC40A1 -2061
KRAS -2044
PABPN1 -2037
NPM1 -2033
CCNE2 -2024
TP53 -2020
ERCC3 -2013
DBP -2002
TICAM1 -1956
AKT2 -1946
AHCY -1945
SLC22A5 -1944
CRBN -1928
NUP214 -1926
AP1G1 -1916
PSMB3 -1915
RPL23 -1913
SRPK2 -1905
AP2A1 -1902
SLC2A9 -1899
UBAP1 -1894
UBE2S -1872
XPO1 -1864
ST6GAL1 -1828
APC -1818
IMPDH1 -1807
RPL24 -1804
RPL38 -1791
HLCS -1769
SLC3A1 -1764
RPS20 -1754
DUSP16 -1750
RPL26 -1747
CHMP5 -1722
ATP1A3 -1706
KPNA4 -1701
CUX1 -1665
ANAPC2 -1639
DCTN1 -1635
TBL1X -1621
ETV6 -1588
PARP6 -1567
ANAPC11 -1544
CDC27 -1529
MUC13 -1524
ARPC5 -1511
PSMC3 -1509
NDC1 -1490
HDAC4 -1478
NAPEPLD -1467
ELL -1439
PRKACB -1429
HDAC10 -1408
LFNG -1376
PIK3R2 -1355
CDK5 -1352
YES1 -1340
LY96 -1339
CHD3 -1321
UBE2I -1318
RPL15 -1313
NFKB2 -1311
LMO7 -1246
DPM1 -1233
CUL5 -1229
TAF3 -1222
TUSC3 -1219
MYO1C -1212
SNF8 -1198
ABI2 -1197
FGFR3 -1195
GYG1 -1167
RPL3 -1165
PSMB4 -1144
CEBPB -1129
RPL17 -1119
SLC27A4 -1101
GATAD2B -1092
ADAMTSL5 -1090
CCNK -1089
CHMP2A -1088
PHF21A -1078
RPS8 -1071
MAN2A1 -1040
PRKAR1B -1038
HSP90AA1 -1030
MUC20 -1019
TAF7 -1012
GNB3 -1008
TRIP11 -990
RPL12 -983
NCKAP1L -972
PRDX2 -961
MDM2 -956
SOS1 -950
RPS25 -937
VPS4B -934
SH3KBP1 -917
DVL2 -905
PSMA7 -892
AMN -881
CHMP2B -878
PTPN11 -867
PRKAR2A -860
TPM4 -822
GALNT1 -816
KREMEN2 -791
CDKN1B -786
SHOC2 -749
PSMB5 -742
AP1S3 -739
SFTPB -720
RPL13 -706
MAPK8 -700
ITGA2B -688
C1QBP -682
ADCY2 -667
CALM1 -655
BAIAP2 -637
POLR2J -603
GCC2 -597
REST -593
ERCC2 -583
TRAF2 -577
NCSTN -554
PRKX -553
SKP1 -544
ATIC -520
UNC93B1 -517
JAG2 -516
RPL5 -495
TAF9 -483
CD19 -472
SLC29A3 -456
PSMD11 -432
TAF11 -429
ALG9 -426
GTF2H4 -406
CAST -381
CYP17A1 -380
TRAF3 -356
HDAC2 -338
NUP160 -329
NUP62 -299
DUSP9 -284
MPRIP -266
B4GALT1 -262
MSH3 -255
GGT1 -250
RPL22L1 -214
TAF2 -206
MNAT1 -205
CDC26 -197
RPS3A -179
CDK5R1 -157
ARID4A -156
RPS27 -152
CCND1 -137
PSMA6 -126
CTBP1 -41
TPM3 -40
RANBP2 -4
KSR1 -1
PRKAR1A 4
NOXO1 10
AP3B1 13
NELFE 26
EML4 27
XRCC6 28
HDAC3 38
CSF2RA 43
RAC1 44
STAT2 76
SLC26A3 83
KITLG 92
DOLK 108
ACACA 118
YWHAE 129
HDAC7 130
ABCA4 138
SLC4A1 141
FMO3 142
SDC2 147
ENTPD1 184
FZR1 201
KPNA5 258
RPL9 261
SLC22A18 262
PPP2R5E 283
FDX2 285
ANAPC4 305
RAP1A 309
PORCN 320
GTF2A1 328
RPL31 330
FGF5 342
SUZ12 346
KREMEN1 364
FEN1 367
PDPK1 399
ATP1A4 412
PACS1 414
RPS26 419
PSMB10 423
E2F3 444
MSH6 450
GNAS 459
PARP4 462
RB1 470
CREB1 474
ARID4B 480
WDR48 543
PRELP 546
TPR 565
APH1A 619
TAF10 626
F2 635
ELOC 645
SLC6A14 695
GNB5 700
F8 735
C1GALT1 742
SIGMAR1 753
UBC 779
TAF1 788
VPS37D 809
CUBN 854
SLC6A20 876
CHMP4A 909
AP1M2 914
AP1B1 940
ELMO2 942
GPC4 952
TCF7L2 959
GPR39 994
IFNGR2 997
HDAC11 1004
GYG2 1023
PML 1051
PSMB1 1054
G6PC3 1108
ALG8 1117
TLR6 1131
PIK3R4 1132
TAF6 1145
CDC16 1175
RNF43 1197
BRAP 1211
CHMP3 1229
MTRR 1240
ADAMTS4 1241
EPS15 1254
GUSB 1260
RANBP1 1308
ALG13 1348
GPR83 1350
KLKB1 1361
NUP133 1362
MLH1 1370
RPL21 1385
BTRC 1386
TBL1XR1 1404
ZFYVE9 1407
ACTR2 1435
TMPRSS2 1456
SGSH 1472
ATM 1503
NCK1 1525
PAPSS2 1548
STRA6 1551
GLB1 1557
CPSF4 1570
GAB1 1575
KAT5 1580
IRAK4 1591
IFNGR1 1624
NF1 1648
MIB1 1650
VTA1 1653
SUGT1 1662
CAMK2D 1711
MGAT4C 1714
PRKACA 1736
PCCB 1766
MTA1 1810
HSPA1A 1835
STX1B 1841
MLST8 1875
PSMB2 1876
FADD 1889
MYC 1892
NMT2 1894
VWF 1933
GNB4 1936
FYN 1937
CYFIP1 1939
MMAA 1953
ALDOB 1990
ANAPC1 1998
POLR2G 2003
ABL1 2023
AP2B1 2029
AGK 2062
YWHAB 2082
SLC7A9 2093
FGF23 2097
IL18 2102
FRS3 2112
DNMT1 2134
RPL22 2142
CAMK2G 2145
SDC1 2160
CYBA 2202
GCLM 2237
ITPR2 2257
FZD8 2263
MAPK14 2269
FOXO3 2282
NRAS 2310
EED 2369
VPS4A 2374
NUP58 2380
DHDDS 2399
CYP24A1 2409
POLR2D 2418
FDX1 2458
MEFV 2468
VPS36 2474
CYSLTR1 2493
DYNLL1 2509
PLCG1 2511
THBS2 2512
GALE 2553
ATRX 2556
SLC26A2 2580
LRAT 2585
COMT 2597
HYAL1 2604
WASF3 2619
CDK9 2631
UGT1A1 2676
CHMP7 2690
CHST3 2703
POLR2A 2705
NUP153 2712
SMAD4 2742
PPP2R5C 2743
CCNE1 2754
ZMYM2 2755
ACE2 2757
NUP43 2808
GANAB 2813
VAV2 2817
RPL36A 2875
ADAMTS7 2880
EIF2AK2 2886
SLC24A4 2892
VPS25 2895
AP1M1 2926
ABCG8 2955
ADAMTSL3 2956
AAAS 2965
SV2A 2966
SLC7A7 2968
PARP1 2974
SRPK1 3007
ARPC1A 3022
WRN 3032
ABCA3 3033
FDXR 3064
STAM2 3080
RPIA 3101
AGGF1 3135
ABCC9 3136
TCN2 3151
CASP8 3157
GSS 3160
CLCN6 3165
SUPT16H 3202
ERLIN1 3212
POMGNT1 3215
DPM3 3217
PARP8 3263
CTNNB1 3272
SUMO1 3308
NUP54 3310
ESR2 3316
CORO1A 3359
DNMT3A 3360
XRCC4 3376
DNA2 3379
RANGAP1 3458
EREG 3467
VAMP1 3484
CYP2R1 3494
IRS1 3502
NTHL1 3521
UBE2D1 3523
SLC5A2 3524
DOCK1 3540
GIPR 3556
RAP1B 3577
SLC35D1 3595
RMI1 3620
DAXX 3635
TRAK1 3646
CNKSR1 3649
NR4A1 3691
CDKN2A 3704
MPDU1 3718
UBE2E1 3733
PTGES3 3734
PAPSS1 3746
ADAMTS1 3770
NEURL1B 3778
BANF1 3790
ARPC3 3797
GYS1 3798
RBBP8 3824
HDAC8 3835
TRADD 3885
PMS2 3890
MYO18A 3903
SLC35A1 3906
OGG1 3917
ANAPC5 3942
ENTPD5 3958
SRC 3962
TBP 3968
BAG4 4019
VPS33B 4043
SLC16A1 4057
MSH2 4066
HHAT 4068
B4GALT7 4091
MRE11 4100
CDK2 4114
CCNT2 4117
GNG5 4123
VPS28 4152
RAD51B 4156
IFNAR1 4161
NUP85 4178
GPC3 4191
CAMK4 4196
KDM1A 4224
SDC3 4241
ERBB3 4249
STAT3 4253
SLC2A10 4273
ACY1 4275
ABCC6 4285
ADCY9 4287
NOTCH3 4292
PSMD12 4303
PALB2 4305
GPC6 4318
CYP21A2 4343
SLCO1B3 4370
GTF2H5 4373
RAE1 4394
VCL 4407
DKK1 4410
ZC3HAV1 4414
GNG7 4426
RNMT 4440
TIRAP 4446
KCNJ11 4499
ANTXR1 4532
NBN 4533
GTF2F2 4556
CAMK2A 4566
PSMD4 4567
HMOX1 4592
POLR2I 4594
DRD5 4609
KLC1 4611
PPP2R1B 4614
CBX1 4668
GAA 4697
ZCRB1 4731
CDK6 4754
SRD5A3 4758
TBXAS1 4766
RBPJ 4794
NUP155 4796
ADCY1 4808
MUC15 4828
F11 4836
KANK1 4837
FZD5 4841
TFDP2 4856
AHCYL1 4874
DUSP8 4879
MMACHC 4886
IMPDH2 4910
PSMD10 4933
PSMD7 4942
ALG6 4943
POLA1 4949
SLC35A3 4972
SLCO2A1 4980
EPM2A 5000
AMER1 5007
ADAMTS13 5043
TYK2 5066
MPI 5076
KAT2A 5077
RFT1 5083
BGN 5087
BRCA1 5107
STAM 5109
AKAP9 5113
PSMD5 5116
MRAS 5118
TUBB 5125
ADORA2B 5127
RBBP7 5134
GPC1 5178
CHST6 5182
SLC24A1 5215
ABCD4 5258
CD36 5264
STAT5A 5288
GPR176 5289
OPLAH 5314
RDH5 5315
GTF2H2 5321
ADORA2A 5330
H2AFX 5356
PARP14 5386
BRCA2 5396
P2RX4 5401
ERLIN2 5405
GSDMD 5413
FOXO1 5418
MMADHC 5435
GTF2A2 5445
ATG7 5453
NCKIPSD 5477
FZD7 5487
PSMB9 5491
NOXA1 5500
GTF2E1 5502
ERBB2 5534
HMGB1 5546
CCNH 5556
SLC37A4 5575
EXT2 5580
RNF213 5584
MVB12A 5589
CYP11A1 5667
F10 5732
RDH12 5744
HLA-A 5777
ZC3HC1 5790
AGTRAP 5793
AP1S1 5804
IDUA 5809
GPC2 5828
NUP93 5831
PARP10 5859
CHMP6 5904
ST3GAL3 5918
HGSNAT 5921
MYD88 5939
SKP2 5946
PSTPIP1 5948
HDAC6 5953
CDC25A 5954
POLR2K 5962
PSMD14 5974
NUP35 5982
THBS1 5988
CYP2U1 5991
BLM 5994
FLT3LG 6000
GTF2H3 6024
RAD51C 6033
DYNLL2 6044
GNE 6051
MTR 6057
ANAPC10 6071
CD4 6074
NUP107 6076
TAF9B 6106
CASP1 6109
CDC23 6113
MAT1A 6114
BARD1 6138
RAD51D 6153
GNG4 6164
APH1B 6168
LIG1 6206
CYFIP2 6224
NEIL3 6230
NOTCH2 6231
ANAPC7 6249
CDC25B 6275
KHK 6286
RAMP2 6288
ANAPC16 6307
FZD6 6312
ADCY7 6316
RAD51 6326
FAM114A2 6340
GALT 6341
NEIL1 6345
CNTRL 6358
BRIP1 6392
F12 6397
ADAMTS9 6402
MTA3 6411
E2F2 6426
CYP19A1 6444
LIG4 6454
CHST14 6461
ADAMTS6 6501
IL1R1 6510
XRCC2 6513
FZD4 6534
MUTYH 6556
STAT5B 6572
PRIM2 6599
TAF12 6601
ABCG5 6607
DUT 6636
WDCP 6637
MAPK3 6640
EXO1 6663
PPP1R3C 6692
POLA2 6695
FGG 6697
GNG10 6779
SLC39A4 6798
NUP210 6802
FGFR2 6811
NCBP2 6823
CDC25C 6825
MAML2 6847
S100A1 6858
CEBPD 6867
PYCARD 6900
PDGFB 6920
ADAMTS2 6939
DNMT3B 6957
PRIM1 6962
ADAMTS10 6971
PARP9 6988
APOA1 6993
CD14 6998
ADAMTSL4 7040
TAF15 7061
APOBEC3G 7066
MC1R 7078
E2F1 7096
NUP37 7100
LMNB1 7101
CTNND1 7129
UBE2C 7137
HSPG2 7157
GALK1 7177
PSIP1 7193
MMAB 7195
RMI2 7209
FGB 7226
NEDD4L 7233
RAD51AP1 7241
SLC2A2 7259
HES1 7265
GCKR 7281
CDH1 7296
RBP4 7308
HIP1 7319
CP 7325
JAK3 7326
FGA 7336
SOD2 7342
C3 7357
MUC5B 7378
TXNIP 7384
SERPING1 7387



Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
721
set Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
setSize 111
pANOVA 3.73e-11
s.dist -0.364
p.adjustANOVA 1.83e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL36AL -6981
ETF1 -6952
RNPS1 -6938
GSPT1 -6825
UPF3A -6189
CASC3 -5986
EIF4G1 -5901
RPL19 -5254
PPP2CA -5168
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
PPP2R1A -4744
RPS11 -4702
UPF1 -4700

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL36AL -6981
ETF1 -6952
RNPS1 -6938
GSPT1 -6825
UPF3A -6189
CASC3 -5986
EIF4G1 -5901
RPL19 -5254
PPP2CA -5168
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
PPP2R1A -4744
RPS11 -4702
UPF1 -4700
RPS19 -4661
RPS28 -4652
RPLP1 -4391
RPS12 -4367
RPL27A -4297
RPLP0 -4290
RPL35A -4159
RPL30 -4081
RPS9 -4028
RPL18 -3961
RPL26L1 -3873
SMG8 -3868
RPS29 -3844
RPL6 -3843
UPF2 -3830
RPL28 -3546
PABPC1 -3543
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
RPS15A -3019
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
SMG1 -2778
RPS27A -2773
SMG7 -2718
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RPS13 -2581
RPL4 -2563
RPS23 -2467
RPL37A -2451
RPL39 -2270
RPL18A -2240
RPL7A -2233
NCBP1 -2151
RPS4Y1 -2120
RPL27 -2070
RPL23 -1913
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
RBM8A -1583
SMG6 -1323
RPL15 -1313
RPL3 -1165
RPL17 -1119
RPS8 -1071
RPL12 -983
MAGOH -969
RPS25 -937
RPL13 -706
SMG5 -654
RPL5 -495
RPL22L1 -214
RPS3A -179
RPS27 -152
DCP1A 40
RPL9 261
RPL31 330
RPS26 419
EIF4A3 1154
RPL21 1385
RPL22 2142
UPF3B 2326
RPL36A 2875
SMG9 3998
PNRC2 5595
PPP2R2A 5688
MAGOHB 5814
NCBP2 6823



Nonsense-Mediated Decay (NMD)

Nonsense-Mediated Decay (NMD)
723
set Nonsense-Mediated Decay (NMD)
setSize 111
pANOVA 3.73e-11
s.dist -0.364
p.adjustANOVA 1.83e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL36AL -6981
ETF1 -6952
RNPS1 -6938
GSPT1 -6825
UPF3A -6189
CASC3 -5986
EIF4G1 -5901
RPL19 -5254
PPP2CA -5168
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
PPP2R1A -4744
RPS11 -4702
UPF1 -4700

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL36AL -6981
ETF1 -6952
RNPS1 -6938
GSPT1 -6825
UPF3A -6189
CASC3 -5986
EIF4G1 -5901
RPL19 -5254
PPP2CA -5168
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
PPP2R1A -4744
RPS11 -4702
UPF1 -4700
RPS19 -4661
RPS28 -4652
RPLP1 -4391
RPS12 -4367
RPL27A -4297
RPLP0 -4290
RPL35A -4159
RPL30 -4081
RPS9 -4028
RPL18 -3961
RPL26L1 -3873
SMG8 -3868
RPS29 -3844
RPL6 -3843
UPF2 -3830
RPL28 -3546
PABPC1 -3543
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
RPS15A -3019
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
SMG1 -2778
RPS27A -2773
SMG7 -2718
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RPS13 -2581
RPL4 -2563
RPS23 -2467
RPL37A -2451
RPL39 -2270
RPL18A -2240
RPL7A -2233
NCBP1 -2151
RPS4Y1 -2120
RPL27 -2070
RPL23 -1913
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
RBM8A -1583
SMG6 -1323
RPL15 -1313
RPL3 -1165
RPL17 -1119
RPS8 -1071
RPL12 -983
MAGOH -969
RPS25 -937
RPL13 -706
SMG5 -654
RPL5 -495
RPL22L1 -214
RPS3A -179
RPS27 -152
DCP1A 40
RPL9 261
RPL31 330
RPS26 419
EIF4A3 1154
RPL21 1385
RPL22 2142
UPF3B 2326
RPL36A 2875
SMG9 3998
PNRC2 5595
PPP2R2A 5688
MAGOHB 5814
NCBP2 6823



Viral mRNA Translation

Viral mRNA Translation
1330
set Viral mRNA Translation
setSize 86
pANOVA 5.18e-11
s.dist -0.41
p.adjustANOVA 2.46e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
DNAJC3 -7131
RPL36AL -6981
RPL19 -5254
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
GRSF1 -4747
RPS11 -4702
RPS19 -4661
RPS28 -4652
RPLP1 -4391
RPS12 -4367
RPL27A -4297
RPLP0 -4290
RPL35A -4159

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DNAJC3 -7131
RPL36AL -6981
RPL19 -5254
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
GRSF1 -4747
RPS11 -4702
RPS19 -4661
RPS28 -4652
RPLP1 -4391
RPS12 -4367
RPL27A -4297
RPLP0 -4290
RPL35A -4159
RPL30 -4081
RPS9 -4028
RPL18 -3961
RPL26L1 -3873
RPS29 -3844
RPL6 -3843
RPL28 -3546
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
RPS15A -3019
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
RPS27A -2773
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RPS13 -2581
RPL4 -2563
RPS23 -2467
RPL37A -2451
RPL39 -2270
RPL18A -2240
RPL7A -2233
RPS4Y1 -2120
RPL27 -2070
RPL23 -1913
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
RPL15 -1313
RPL3 -1165
RPL17 -1119
RPS8 -1071
RPL12 -983
RPS25 -937
RPL13 -706
RPL5 -495
RPL22L1 -214
RPS3A -179
RPS27 -152
RPL9 261
RPL31 330
RPS26 419
RPL21 1385
RPL22 2142
RPL36A 2875



Influenza Infection

Influenza Infection
511
set Influenza Infection
setSize 151
pANOVA 6.29e-11
s.dist -0.309
p.adjustANOVA 2.89e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
CALR -7142
DNAJC3 -7131
CANX -7092
RPL36AL -6981
TGFB1 -6934
SEC13 -6812
KPNA1 -6701
RAN -6476
CLTA -6439
KPNB1 -6379
IPO5 -6366
POM121 -6353
CLTC -6220
POM121C -6045
ISG15 -5488
POLR2L -5471
POLR2F -5283
NUP205 -5275
RPL19 -5254
RPS7 -5138

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CALR -7142
DNAJC3 -7131
CANX -7092
RPL36AL -6981
TGFB1 -6934
SEC13 -6812
KPNA1 -6701
RAN -6476
CLTA -6439
KPNB1 -6379
IPO5 -6366
POM121 -6353
CLTC -6220
POM121C -6045
ISG15 -5488
POLR2L -5471
POLR2F -5283
NUP205 -5275
RPL19 -5254
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
NUP188 -4991
FAU -4990
RPL14 -4978
RPS5 -4778
NUP88 -4777
GRSF1 -4747
NUP50 -4733
RPS11 -4702
POLR2E -4667
RPS19 -4661
RPS28 -4652
KPNA2 -4575
SEH1L -4472
RPLP1 -4391
RPS12 -4367
KPNA3 -4357
RPL27A -4297
RPLP0 -4290
RPL35A -4159
RPL30 -4081
RPS9 -4028
RPL18 -3961
RPL26L1 -3873
RPS29 -3844
RPL6 -3843
NUP98 -3764
SLC25A6 -3733
POLR2B -3699
POLR2H -3593
RPL28 -3546
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
POLR2C -3425
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
GTF2F1 -3103
RPS15A -3019
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
RPS27A -2773
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RPS13 -2581
RPL4 -2563
RPS23 -2467
RPL37A -2451
RPL39 -2270
RPL18A -2240
RPL7A -2233
RPS4Y1 -2120
RPL27 -2070
PABPN1 -2037
NUP214 -1926
RPL23 -1913
XPO1 -1864
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
KPNA4 -1701
NDC1 -1490
RPL15 -1313
RPL3 -1165
RPL17 -1119
RPS8 -1071
HSP90AA1 -1030
RPL12 -983
RPS25 -937
RPL13 -706
POLR2J -603
RPL5 -495
NUP160 -329
NUP62 -299
RPL22L1 -214
RPS3A -179
RPS27 -152
RANBP2 -4
KPNA5 258
RPL9 261
RPL31 330
RPS26 419
TPR 565
NUP133 1362
RPL21 1385
CPSF4 1570
HSPA1A 1835
POLR2G 2003
RPL22 2142
NUP58 2380
POLR2D 2418
POLR2A 2705
NUP153 2712
NUP43 2808
RPL36A 2875
EIF2AK2 2886
AAAS 2965
PARP1 2974
NUP54 3310
NUP85 4178
RAE1 4394
GTF2F2 4556
POLR2I 4594
NUP155 4796
NUP93 5831
POLR2K 5962
NUP35 5982
NUP107 6076
NUP210 6802
NUP37 7100



rRNA processing in the nucleus and cytosol

rRNA processing in the nucleus and cytosol
1370
set rRNA processing in the nucleus and cytosol
setSize 184
pANOVA 7.82e-11
s.dist -0.278
p.adjustANOVA 3.47e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL36AL -6981
MPHOSPH10 -6827
DDX49 -6809
EXOSC6 -6503
RRP36 -6354
RIOK3 -6332
UTP14C -6243
UTP4 -6111
UTP14A -5799
PNO1 -5758
CSNK1D -5722
LTV1 -5474
GNL3 -5332
RPL19 -5254
DHX37 -5250
NOP14 -5209
RPS7 -5138
RRP1 -5133
UBA52 -5068
RPL11 -5032

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL36AL -6981
MPHOSPH10 -6827
DDX49 -6809
EXOSC6 -6503
RRP36 -6354
RIOK3 -6332
UTP14C -6243
UTP4 -6111
UTP14A -5799
PNO1 -5758
CSNK1D -5722
LTV1 -5474
GNL3 -5332
RPL19 -5254
DHX37 -5250
NOP14 -5209
RPS7 -5138
RRP1 -5133
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
NOP10 -4958
NOL9 -4954
IMP4 -4940
RPS5 -4778
BMS1 -4769
EXOSC5 -4766
RPS11 -4702
RPS19 -4661
RPS28 -4652
IMP3 -4633
UTP18 -4476
RPLP1 -4391
BOP1 -4381
RPS12 -4367
RPL27A -4297
RPLP0 -4290
TEX10 -4283
NHP2 -4261
WDR43 -4193
RPL35A -4159
RPL30 -4081
DDX47 -4068
RPS9 -4028
RIOK2 -4018
RPL18 -3961
DDX52 -3894
RPL26L1 -3873
TRMT112 -3869
NOP2 -3859
RPS29 -3844
RPL6 -3843
NOL12 -3773
NOB1 -3772
ISG20L2 -3623
EBNA1BP2 -3613
RPL28 -3546
RPSA -3520
PES1 -3505
RPL8 -3467
RPS4X -3464
RPS2 -3462
EXOSC3 -3453
RPL29 -3450
RPL32 -3448
RPL36 -3432
XRN2 -3427
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
RPS15A -3019
GAR1 -3015
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
PELP1 -2894
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
UTP20 -2811
RPS27A -2773
FCF1 -2713
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
BYSL -2637
RPL41 -2635
RRP9 -2591
RPS13 -2581
RPL4 -2563
UTP15 -2509
ERI1 -2490
RPS23 -2467
RPL37A -2451
RPL39 -2270
RPL18A -2240
RPL7A -2233
NIP7 -2165
RPS4Y1 -2120
RPL27 -2070
PWP2 -2005
RPL23 -1913
NCL -1840
UTP6 -1836
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
DIS3 -1573
NOC4L -1552
FBL -1548
SENP3 -1399
UTP11 -1337
HEATR1 -1324
RPL15 -1313
DKC1 -1249
RPL3 -1165
NOP56 -1145
RPL17 -1119
RPS8 -1071
RPL12 -983
RCL1 -942
RPS25 -937
TSR1 -851
TBL3 -794
RPL13 -706
RPL5 -495
TSR3 -466
EXOSC10 -341
THUMPD1 -270
DDX21 -256
RPL22L1 -214
RPS3A -179
RPS27 -152
SNU13 -129
RPL9 261
RPL31 330
RPS26 419
EXOSC8 472
RBM28 771
KRR1 924
RPP14 1309
RPL21 1385
RPP30 1439
RPP38 1564
RPP40 1770
NOL6 1999
RRP7A 2006
FTSJ3 2052
WDR18 2127
RPL22 2142
DIMT1 2382
RIOK1 2711
RPL36A 2875
EXOSC4 3220
CSNK1E 3247
EXOSC9 3293
PDCD11 3334
NAT10 3342
C1D 3482
EXOSC1 3486
WDR75 3573
EXOSC2 3779
WDR12 3814
NOL11 4020
UTP3 4280
DCAF13 4652
WDR46 4709
EXOSC7 5196
NOP58 5612
MPHOSPH6 5619
WDR3 5692
WDR36 5735
LAS1L 7022
EMG1 7347



Peptide chain elongation

Peptide chain elongation
784
set Peptide chain elongation
setSize 86
pANOVA 8.24e-11
s.dist -0.405
p.adjustANOVA 3.55e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL36AL -6981
RPL19 -5254
RPS7 -5138
UBA52 -5068
EEF2 -5049
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
RPS11 -4702
RPS19 -4661
RPS28 -4652
RPLP1 -4391
RPS12 -4367
RPL27A -4297
RPLP0 -4290
RPL35A -4159
EEF1A1 -4138

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL36AL -6981
RPL19 -5254
RPS7 -5138
UBA52 -5068
EEF2 -5049
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
RPS11 -4702
RPS19 -4661
RPS28 -4652
RPLP1 -4391
RPS12 -4367
RPL27A -4297
RPLP0 -4290
RPL35A -4159
EEF1A1 -4138
RPL30 -4081
RPS9 -4028
RPL18 -3961
RPL26L1 -3873
RPS29 -3844
RPL6 -3843
RPL28 -3546
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
RPS15A -3019
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
RPS27A -2773
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RPS13 -2581
RPL4 -2563
RPS23 -2467
RPL37A -2451
RPL39 -2270
RPL18A -2240
RPL7A -2233
RPS4Y1 -2120
RPL27 -2070
RPL23 -1913
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
RPL15 -1313
RPL3 -1165
RPL17 -1119
RPS8 -1071
RPL12 -983
RPS25 -937
RPL13 -706
RPL5 -495
RPL22L1 -214
RPS3A -179
RPS27 -152
RPL9 261
RPL31 330
RPS26 419
RPL21 1385
RPL22 2142
RPL36A 2875



Immune System

Immune System
502
set Immune System
setSize 1374
pANOVA 8.91e-11
s.dist -0.106
p.adjustANOVA 3.72e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
HSPA5 -7144
CALR -7142
SEC24D -7134
DNAJC3 -7131
HSP90B1 -7129
CANX -7092
PDIA3 -7086
VASP -7075
PLPP5 -7074
KLHL21 -7069
UBE2J1 -7068
ATP6V0B -7064
MAP3K8 -7060
NCR3LG1 -7048
MAGT1 -7045
CNN2 -7036
SEC61A1 -7030
ERP44 -7023
SQSTM1 -7010
EIF4A1 -6995

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
HSPA5 -7144
CALR -7142
SEC24D -7134
DNAJC3 -7131
HSP90B1 -7129
CANX -7092
PDIA3 -7086
VASP -7075
PLPP5 -7074
KLHL21 -7069
UBE2J1 -7068
ATP6V0B -7064
MAP3K8 -7060
NCR3LG1 -7048
MAGT1 -7045
CNN2 -7036
SEC61A1 -7030
ERP44 -7023
SQSTM1 -7010
EIF4A1 -6995
SNRPA1 -6983
LAMP1 -6982
ATP6V0A1 -6979
CEACAM1 -6974
LAMP2 -6966
ASB2 -6960
STX3 -6959
SEC61B -6958
PIK3AP1 -6957
OAS1 -6953
CTSL -6951
ARSB -6939
IL17RB -6937
GGH -6936
TGFB1 -6934
CCR6 -6932
LGALS3 -6923
ATP6V1D -6922
SHC1 -6910
ATP6V0D1 -6908
MLEC -6902
CCL20 -6885
P4HB -6884
ATP6V0A2 -6880
S100A11 -6865
P2RX1 -6853
BRI3 -6843
ACTG1 -6841
SEC24A -6839
FLNA -6833
GNS -6813
SEC13 -6812
PNP -6810
NDUFC2 -6804
TRIB3 -6798
C4BPB -6787
CYSTM1 -6768
BTN2A1 -6754
NEU1 -6752
NFATC3 -6750
HNRNPF -6735
VCP -6720
IRAK2 -6713
CSF1 -6711
KPNA1 -6701
FTL -6697
PYGB -6693
SIAH2 -6666
PSMF1 -6663
ASAH1 -6648
SOCS5 -6643
UBE2Q1 -6639
KIF5A -6634
ATP6V0E1 -6622
SURF4 -6593
RAPGEF1 -6586
HSPA9 -6580
TOLLIP -6576
NF2 -6559
RALA -6548
WASL -6543
DUSP3 -6541
IGF2R -6540
FUCA2 -6538
DNM2 -6535
DNAJC5 -6522
CD55 -6517
TMBIM1 -6493
APP -6492
VHL -6491
TRIM5 -6483
KEAP1 -6482
NFKBIB -6474
EP300 -6470
ALDOA -6463
MAPKAPK2 -6461
HEXB -6455
CLEC10A -6451
PSME4 -6450
DDX3X -6449
HNRNPA2B1 -6445
ICAM3 -6441
CLTA -6439
NFKBIA -6437
PSMD2 -6435
DDOST -6429
EIF4G2 -6418
CDK13 -6415
KCMF1 -6393
KPNB1 -6379
PJA2 -6376
ARIH2 -6355
POM121 -6353
BCL2L1 -6349
UBR4 -6345
ATAD3B -6334
UBE2O -6331
KIF3B -6315
GALNS -6314
TIMP1 -6294
CTSA -6288
TAX1BP1 -6281
ATP6V1E1 -6271
PRDX4 -6268
CD22 -6256
LCK -6250
RBBP6 -6244
SEC24C -6236
UBE2J2 -6232
MAP3K1 -6230
SMURF1 -6229
CLTC -6220
SH3RF1 -6212
NPC2 -6207
IFI30 -6187
ATF2 -6175
PGAM1 -6174
RAP2B -6173
SMAD3 -6145
TRIM26 -6126
TMC6 -6114
CD63 -6107
PTPRJ -6103
PDXK -6100
ARPC4 -6094
IRF9 -6092
ITCH -6089
ITPR3 -6088
ATP6V0C -6086
CYLD -6066
MASP1 -6062
DEGS1 -6054
OAS3 -6048
MYLIP -6047
POM121C -6045
UBE3C -6041
TPP2 -6027
MALT1 -6026
ARF1 -6021
COLEC11 -5996
DUSP4 -5977
PSMD6 -5951
IKBKG -5946
FBXW5 -5945
OTUD5 -5944
SRP14 -5938
MAPKAP1 -5936
MVP -5935
PRKCSH -5934
PTPN23 -5932
ATP6V1C2 -5929
CCT2 -5926
BPIFB6 -5923
ARL8A -5922
MYO9B -5920
DDX41 -5919
RNF130 -5910
EIF4G1 -5901
UBE2F -5885
THOP1 -5882
DOK3 -5877
RORA -5875
EIF4G3 -5852
CAPN1 -5850
ECSIT -5840
ADAM17 -5836
ANO6 -5826
IFITM3 -5819
KIF2A -5815
RAB7A -5810
DIAPH1 -5806
PSMA2 -5801
PVR -5786
RIPK2 -5779
MAPKAPK3 -5773
SEC31A -5766
UBE2G1 -5763
PPP2R5A -5740
CFL1 -5737
ELK1 -5733
PSMA1 -5730
WASF1 -5712
CBL -5708
MKRN1 -5695
SNAP23 -5681
STAT1 -5668
IQGAP1 -5663
CRK -5650
GLA -5640
PRKCD -5638
PANX1 -5636
POLR3E -5626
CCT8 -5605
PITPNA -5591
ATP6V1B2 -5574
PSMC1 -5564
RAF1 -5557
CASP10 -5555
TALDO1 -5554
HECTD1 -5553
MAP3K3 -5546
HRAS -5543
MAPK12 -5538
PSMD3 -5535
ITGB5 -5532
CDC34 -5516
TRIM8 -5512
PRKCE -5510
GRB10 -5504
TRIM25 -5492
ISG15 -5488
FBXO31 -5485
PSME2 -5481
CD58 -5480
LRRFIP1 -5477
SEC24B -5475
POLR2L -5471
IDH1 -5470
SOCS6 -5467
IRS2 -5461
MEX3C -5460
NCF2 -5438
BRK1 -5431
CLCF1 -5429
KIF5B -5426
FTH1 -5419
SOS2 -5417
TNFRSF12A -5405
PPM1B -5398
TXNDC5 -5385
TRAF7 -5369
ATP6V1G1 -5352
PSMD1 -5351
PTPN12 -5326
IQGAP2 -5323
FBXO32 -5299
ACTR3 -5296
RHOA -5294
MYO10 -5290
POLR2F -5283
NUP205 -5275
ILF2 -5258
CASP3 -5257
SMURF2 -5253
CASP9 -5247
ASB6 -5243
PELI1 -5222
PIK3C3 -5220
PSAP -5218
CTSB -5204
FKBP1A -5189
MIF -5176
FOS -5174
TBK1 -5169
PPP2CA -5168
ACTR1A -5162
ISG20 -5154
PKM -5137
PPP2R5B -5131
RNF6 -5120
VAMP2 -5088
AAMP -5076
UBA52 -5068
MAPK1 -5066
ACTB -5057
EEF2 -5049
ZAP70 -5027
RAP1GAP -4998
NUP188 -4991
POLR1C -4986
VAMP8 -4969
BPIFB2 -4967
TNFSF4 -4966
JAK1 -4963
PAK2 -4957
CAB39 -4956
ATP6V1C1 -4946
IL6R -4943
PSEN1 -4938
ATF1 -4925
GPI -4904
NOS3 -4903
VAPA -4898
PSMB6 -4888
WSB1 -4879
PSMC6 -4878
RAB31 -4876
KLHL42 -4874
CAPZA1 -4855
ORAI2 -4848
OSTF1 -4843
CTSK -4821
RNF19A -4816
PSMC4 -4808
NUP88 -4777
PIK3CD -4759
SH2B3 -4752
DSP -4746
SIPA1 -4745
PPP2R1A -4744
HMOX2 -4742
TCP1 -4735
NUP50 -4733
MYH9 -4726
PTEN -4721
FBXO44 -4694
GLIPR1 -4691
RNF123 -4681
MMP2 -4677
RILP -4675
POLR2E -4667
UBE2V1 -4655
HSPA8 -4654
VAV3 -4642
FAF2 -4640
PSMD9 -4638
TSPAN14 -4626
TANK -4621
AP2M1 -4603
PGM1 -4600
NKIRAS2 -4598
GBP2 -4577
KPNA2 -4575
OSCAR -4571
PPP2CB -4523
BATF -4520
POLR1D -4516
MAP2K4 -4505
TRIP12 -4503
RNF19B -4500
VAT1 -4497
ABI1 -4478
SEH1L -4472
BCL10 -4471
EIF4E2 -4465
VEGFA -4456
CTSC -4446
PPIA -4443
ARPC1B -4429
HSP90AB1 -4426
ATP6V1H -4423
MAP2K7 -4399
MAPK7 -4382
PIK3R1 -4376
PSMB7 -4372
KPNA3 -4357
MIB2 -4356
PTK2 -4346
IL18BP -4340
UBE2M -4337
ITPR1 -4321
ITGAV -4312
BCL6 -4296
RPLP0 -4290
AIP -4270
UBB -4263
TRIM4 -4229
PLEKHO2 -4227
RNF126 -4225
PSMA4 -4211
AP1S2 -4204
TOM1 -4199
ARG1 -4179
PPP3R1 -4176
YPEL5 -4173
ASB1 -4171
IFI6 -4166
HIF1A -4165
XRCC5 -4164
IP6K2 -4148
ITGB1 -4145
EEF1A1 -4138
CUL1 -4129
GAB2 -4127
MAP2K1 -4120
CSK -4113
DHX9 -4112
COPB1 -4098
LCN2 -4096
PIM1 -4092
PSMC5 -4091
CAP1 -4085
PTPN14 -4062
PPP3CB -4060
SEC61G -4052
UBE2D3 -3997
UBA5 -3984
CNPY3 -3981
NME2 -3974
ORM1 -3973
ADAR -3971
IL11 -3967
DCTN2 -3957
SARM1 -3956
FBXL20 -3941
CKAP4 -3939
TIMP2 -3938
TTR -3924
DYNC1LI2 -3897
ASB7 -3889
CREBBP -3888
TAB2 -3878
DUSP7 -3870
RPS6KA1 -3857
FBXO11 -3853
BCL2L11 -3834
ASB4 -3822
PSME3 -3813
PTPN2 -3809
FBXW11 -3784
ATP6V1A -3777
HUWE1 -3769
PLCG2 -3766
NUP98 -3764
LIFR -3759
HERC2 -3739
RBX1 -3714
CPNE1 -3710
CNTF -3706
LAT -3697
NLRC4 -3690
MTOR -3683
MCL1 -3681
PDAP1 -3657
GAN -3641
CD101 -3638
DCTN5 -3634
SH2B1 -3615
DYNC1H1 -3614
TXN -3611
LAG3 -3610
IL20RB -3604
TRIM41 -3598
ROCK1 -3594
POLR2H -3593
LIF -3587
CDKN1A -3580
TMEM179B -3567
KCTD7 -3550
SIRPA -3538
TRIM62 -3535
COMMD9 -3531
PRLR -3529
JUNB -3526
NFKB1 -3507
MYO5A -3500
AP2A2 -3499
UBE3D -3465
TRIM37 -3461
TRIM39 -3437
GOLGA7 -3421
DUSP6 -3376
KLC2 -3375
WASF2 -3366
CHUK -3364
STBD1 -3361
HSPA6 -3353
SIAH1 -3347
MAP2K3 -3342
ATG12 -3333
STIM1 -3329
MEF2A -3308
RNF14 -3295
MAOA -3288
KLHL2 -3269
TRIM11 -3250
CD59 -3245
SMARCA4 -3226
EDA2R -3214
IRF4 -3173
HEBP2 -3167
ZNRF2 -3150
PPL -3149
UBE2L3 -3143
PA2G4 -3141
ENAH -3139
SEM1 -3130
RAB5C -3129
LNPEP -3128
FN1 -3115
PSMA3 -3078
CUL3 -3056
GRB2 -3047
LYN -3038
TRIM35 -3032
RPS6KA3 -3030
LAIR1 -3025
ABL2 -3020
ELOB -3004
TXLNA -3002
SAR1B -2973
WIPF2 -2965
APOB -2964
PLAU -2962
AKT1 -2958
TMEM30A -2956
RCHY1 -2947
JUN -2934
IKBKB -2931
PSMD8 -2928
AP2S1 -2922
CBLB -2897
RBCK1 -2891
RIPK1 -2886
STK11IP -2838
CD99 -2817
PIK3CA -2813
GRN -2805
TOMM70 -2797
NCKAP1 -2788
VAMP7 -2787
DYNC1I2 -2780
ELMO1 -2779
RPS27A -2773
EEA1 -2764
RHOG -2756
JAK2 -2719
SEC23A -2717
PSMA5 -2715
HERC1 -2688
ADAM10 -2671
UBE2E3 -2654
S100P -2653
RNF34 -2647
RNF115 -2643
RELA -2632
LAMTOR3 -2631
FBXL14 -2614
RHOF -2600
PIK3CB -2588
UBE2B -2586
PSMD13 -2577
MAP3K14 -2575
FBXW7 -2564
UBE3A -2547
FBXW10 -2540
B2M -2523
DYNC1LI1 -2519
POLR3H -2496
SERPINB6 -2474
SP100 -2455
ATP11B -2420
QPCT -2416
CANT1 -2398
PSMC2 -2389
STX1A -2377
TLR9 -2371
MAP2K6 -2351
PSME1 -2348
IFNAR2 -2313
PRKDC -2300
PIK3R3 -2279
PRCP -2276
POLR3B -2273
UBA6 -2266
NECTIN2 -2239
PTPN4 -2238
IRAK1 -2218
C8G -2213
ARPC2 -2209
CDC42 -2172
ARHGAP9 -2170
PPP2R5D -2117
FBXL19 -2110
PRR5 -2094
RICTOR -2076
CRISPLD2 -2075
KLRK1 -2060
AGER -2057
POLR3A -2056
KRAS -2044
HECTD3 -2034
IFNLR1 -2031
FBXL3 -2027
GDI2 -2026
TP53 -2020
IST1 -2001
ANAPC13 -1975
UBE2W -1973
TICAM1 -1956
AKT2 -1946
DCTN4 -1937
NUP214 -1926
AP1G1 -1916
PSMB3 -1915
AP2A1 -1902
MAPK13 -1875
UBE2S -1872
UNC13D -1871
PELI2 -1870
RNF138 -1859
FBXO9 -1843
SDCBP -1822
LTN1 -1814
IMPDH1 -1807
PILRA -1760
BTNL9 -1735
POLR3C -1730
LTBR -1719
NPEPPS -1702
KPNA4 -1701
TRIM71 -1686
MMP3 -1680
CAND1 -1658
ANAPC2 -1639
DCTN1 -1635
HAVCR2 -1603
CAPZA2 -1549
ANAPC11 -1544
STAT6 -1541
SLC2A3 -1535
CDC27 -1529
MUC13 -1524
STOM -1523
ARIH1 -1512
ARPC5 -1511
PSMC3 -1509
FBXL18 -1507
LGALS9 -1496
NDC1 -1490
EGR1 -1475
MX2 -1456
PRKACB -1429
IL23A -1422
ORAI1 -1417
SEC61A2 -1397
UBR2 -1393
PIK3R2 -1355
SOCS2 -1346
YES1 -1340
LY96 -1339
TNIP2 -1314
NFKB2 -1311
SPSB2 -1306
EDA -1292
VRK3 -1278
UBA3 -1275
ICAM1 -1264
BRWD1 -1263
HERC4 -1256
QSOX1 -1250
LMO7 -1246
ATP6AP2 -1245
ORM2 -1240
CUL5 -1229
KLHL11 -1223
MYO1C -1212
ABI2 -1197
ADAM8 -1193
MGRN1 -1188
CAPZB -1169
GYG1 -1167
ERAP1 -1151
RPS6KA2 -1149
PSMB4 -1144
FBXL12 -1137
TRIM38 -1131
MT2A -1121
ITK -1112
RAP2C -1109
ASB8 -1103
BOLA2 -1094
TNFSF13 -1035
OSBPL1A -1032
HSP90AA1 -1030
MUC20 -1019
IFI27 -1017
KLHL5 -991
NCKAP1L -972
RLIM -971
UBE2Z -964
RNF114 -963
SOS1 -950
HNRNPDL -933
CD79A -929
DDX58 -927
MICB -918
SH3KBP1 -917
UBE2D2 -913
LCP1 -901
PSMA7 -892
YWHAZ -885
COTL1 -877
FBXL13 -870
ATP6V1F -868
PTPN11 -867
AMPD3 -829
GHDC -827
ABCE1 -819
IKBKE -787
CDKN1B -786
WWP1 -779
LAMTOR1 -774
PSMB5 -742
AP1S3 -739
UBE2G2 -718
SNAP29 -703
RNASET2 -701
MAPK8 -700
VAMP3 -698
DNAJC13 -677
CALM1 -655
TNFRSF9 -640
BAIAP2 -637
IL22RA1 -612
RNF7 -611
ASB18 -601
MAN2B1 -600
SIGLEC10 -594
INPPL1 -587
TRAF2 -577
RASGRP3 -569
DHX36 -566
TAP2 -558
NCSTN -554
SKP1 -544
IFITM1 -540
ATP6V1E2 -534
ZEB1 -533
UNC93B1 -517
BIRC2 -499
LRR1 -494
STX4 -491
CD19 -472
PAFAH1B2 -471
RELB -469
PSMD11 -432
TAP1 -414
TRIM29 -412
UBE2R2 -386
RNF4 -377
RAB18 -372
TNFSF15 -357
TRAF3 -356
IRF2 -335
NUP160 -329
DCTN6 -318
ADGRE5 -313
UBAC1 -312
AREL1 -303
NUP62 -299
FBXW2 -294
PIAS1 -272
B4GALT1 -262
CMTM6 -259
PGRMC1 -242
GMFG -220
KLHL25 -215
CDC26 -197
IL17RA -186
CASP4 -184
KCTD6 -178
TRIM46 -171
REL -160
LAMTOR2 -148
CCND1 -137
PILRB -136
TAPBP -130
PSMA6 -126
CPN2 -110
FBXO2 -78
CRACR2A -75
PRDX6 -54
CREG1 -47
RANBP2 -4
FBXO10 18
AHSG 25
XRCC6 28
BTBD1 37
CSF2RA 43
RAC1 44
CXADR 72
STAT2 76
DGAT1 111
IL27RA 122
CTSE 125
RNF135 126
NLRP1 136
FBXO30 137
NKIRAS1 150
ICAM4 161
TCIRG1 180
NEDD4 196
FZR1 201
MAPK11 251
KPNA5 258
PGM2 263
IL16 266
PPP2R5E 283
TNFRSF25 296
ANAPC4 305
RAP1A 309
STK10 333
IL1RL1 347
CUL2 359
CD226 372
FCER1G 380
PPP3CA 381
UBE2K 383
PDPK1 399
IL12RB1 421
PSMB10 423
RAPGEF4 438
CREB1 474
UBA1 516
COLEC12 522
CRKL 524
TPR 565
CCL22 584
IL15 586
ZNRF1 590
CYB5R3 600
FRK 602
FBXL15 612
RNF25 622
F2 635
ELOC 645
LAT2 670
KCNAB2 675
POLR3F 688
ATP6V1G2 690
NOS1 709
BST1 713
ICAM5 728
GHR 733
STXBP2 740
ATP6V0D2 747
TNFSF9 763
CSTB 776
UBC 779
SLC27A2 829
SEC22B 859
IRF3 862
FBXW9 890
IL1R2 892
AP1M2 914
NFKBIE 919
AP1B1 940
ELMO2 942
FBXO7 947
CD40 949
PCBP2 974
CRCP 979
NAPRT 988
IFNGR2 997
RNF220 999
LGMN 1001
PAK1 1031
PML 1051
PSMB1 1054
SPSB1 1077
JAML 1090
PECAM1 1098
SIRPB1 1105
TLR6 1131
PIK3R4 1132
EIF4A3 1154
CD74 1162
NANOG 1164
CDC16 1175
CIITA 1176
HECTD2 1208
OPRD1 1233
PLD3 1239
GUSB 1260
POU2F1 1266
APAF1 1277
CCNF 1291
RAB6A 1296
PPIE 1333
GBP4 1334
MOSPD2 1344
MICA 1351
NUP133 1362
BTRC 1386
ADGRG3 1417
UBE4A 1433
ACTR2 1435
IL17RC 1440
RNF217 1448
DCTN3 1457
CXCR2 1464
ATP11A 1486
GSN 1496
CTSS 1499
SIGIRR 1500
NCK1 1525
POLR3G 1545
GLB1 1557
USP41 1563
LIMK1 1565
IRAK4 1591
TRAF6 1597
RAB3D 1600
IFNGR1 1624
RAB10 1625
SUGT1 1662
HTN1 1687
MAVS 1695
CAMK2D 1711
PRKACA 1736
MAPK9 1760
SCAMP1 1817
HSPA1A 1835
UBE2N 1836
GLMN 1839
KIF3C 1853
HERC5 1855
MLST8 1875
PSMB2 1876
CLEC7A 1881
FADD 1889
MYC 1892
ITGAX 1919
BCL2 1925
PDE12 1929
FYN 1937
CYFIP1 1939
IL6ST 1965
PTPRN2 1971
TNFSF14 1985
LRRC41 1992
ANAPC1 1998
ABL1 2023
AP2B1 2029
YWHAB 2082
IL18 2102
ATP7A 2111
UBE2E2 2114
CAMK2G 2145
KLRD1 2155
SDC1 2160
CTSV 2161
AGL 2176
SVIP 2180
SERPINB1 2181
CYBA 2202
ITPR2 2257
KIF5C 2266
MAPK14 2269
KLRG1 2270
GSTO1 2273
FOXO3 2282
EIF4E3 2306
NRAS 2310
MGST1 2313
JUP 2314
CARD9 2322
NUP58 2380
SPTAN1 2385
ARMC8 2401
SLC15A4 2407
UBR1 2428
UBOX5 2442
RNF111 2443
EVL 2467
MEFV 2468
EIF4E 2473
HTN3 2502
DYNLL1 2509
PLCG1 2511
PLAC8 2524
GBP5 2542
TAB3 2566
FSCN1 2591
WASF3 2619
UBE2Q2 2642
UFL1 2652
PJA1 2653
CPPED1 2657
FUCA1 2696
NUP153 2712
TNFRSF14 2741
PPP2R5C 2743
HLA-B 2764
PAG1 2774
NUP43 2808
MID1 2810
CTSD 2812
VAV2 2817
IRF5 2827
FLNB 2867
BST2 2868
ARSA 2878
EIF2AK2 2886
RAB5B 2913
FBXL8 2924
AP1M1 2926
ATG5 2931
KBTBD8 2943
MAPK10 2952
AAAS 2965
RAB27A 3011
ARPC1A 3022
ASB3 3026
DTX4 3048
PIN1 3074
RPS6KA5 3086
TRAPPC1 3089
KLC3 3105
FBXL22 3108
PDCD4 3127
POLR3K 3152
CASP8 3157
RAB4B 3174
UBE2D4 3190
SLC2A5 3250
CTNNB1 3272
IFITM2 3282
KIF3A 3299
CPNE3 3303
SUMO1 3308
NUP54 3310
RAP1GAP2 3326
KLHL20 3344
IL4R 3348
TMEM63A 3357
UBE2V2 3369
STUB1 3373
DBNL 3382
PDZD11 3385
APRT 3389
TRIM50 3393
HERC3 3443
BIRC3 3477
C5AR2 3489
IRS1 3502
GBP1 3503
UBE2D1 3523
SLC11A1 3527
DOCK1 3540
FBXO15 3559
MANBA 3572
RAP1B 3577
TIFA 3587
TRPC1 3602
PTGES2 3607
PTPN1 3622
FBXO27 3623
CXCL8 3625
RAB14 3647
ATOX1 3659
CRLF1 3695
KLHL9 3712
FBXW8 3716
CST3 3732
UBE2E1 3733
IL7 3739
UBE2A 3752
MAP3K7 3767
ARPC3 3797
LYZ 3804
DYNLT1 3809
IL17RE 3847
SPTBN2 3883
HVCN1 3884
ACAA1 3886
KLC4 3897
INPP5D 3931
FBXO6 3932
ANAPC5 3942
SRC 3962
SERPINA1 4014
FABP5 4021
RAB24 4024
CPN1 4039
PLD2 4048
NBEAL2 4086
MRE11 4100
TRIM21 4105
MTAP 4110
IFNAR1 4161
NUP85 4178
FBXO4 4180
HLA-H 4193
CASP2 4204
CTF1 4240
RNF216 4252
STAT3 4253
C2 4264
KLHL13 4291
PSMD12 4303
RAB3A 4309
IL12A 4312
CPB2 4337
SAMHD1 4346
TNFAIP3 4359
METTL7A 4368
CUL7 4377
SIKE1 4383
RAE1 4394
VCL 4407
CSNK2B 4415
TIRAP 4446
UBE3B 4451
POLR3D 4454
CD8A 4468
ERAP2 4482
PLAUR 4485
PTAFR 4486
ATP6V1B1 4549
TRIM69 4557
ACLY 4562
CAMK2A 4566
PSMD4 4567
RHOU 4579
HMOX1 4592
DPP7 4601
KLC1 4611
PPP2R1B 4614
ANPEP 4690
IL11RA 4693
GAA 4697
APEH 4698
NFATC2 4720
C7 4745
IL15RA 4756
FBXO22 4762
AGPAT2 4769
TNFRSF13C 4785
NUP155 4796
FBXL4 4801
TNFRSF1A 4807
TNFSF12 4816
MUC15 4828
AHCYL1 4874
EPPIN 4893
PYGL 4903
IMPDH2 4910
PSMD10 4933
PSMD7 4942
NLRC5 4976
FBXO21 4978
COMMD3 4983
CAT 5018
PELI3 5019
CD46 5036
ORMDL3 5040
ALPK1 5041
SOCS1 5053
ICOSLG 5061
TYK2 5066
KLHL22 5084
PSMD5 5116
TUBB 5125
ASB9 5150
LPCAT1 5166
GSTA2 5171
BIRC5 5174
IRF1 5197
RBSN 5208
C4BPA 5221
KIF18A 5234
TRIM3 5236
CD36 5264
GM2A 5280
STAT5A 5288
MX1 5298
DERA 5319
PTPN9 5324
IL13RA1 5359
IL1RAP 5361
UBE2H 5369
MADCAM1 5372
TBC1D10C 5382
OSMR 5392
GSDMD 5413
FOXO1 5418
IL32 5419
PFKL 5437
NOD1 5449
ATG7 5453
DTX3L 5458
NCKIPSD 5477
NPDC1 5488
PSMB9 5491
XAF1 5517
CENPE 5538
HMGB1 5546
VNN1 5548
CFD 5558
ULBP1 5560
ACTR10 5570
RNF213 5584
EIF4A2 5593
NIT2 5596
BLMH 5642
CLU 5647
CDC20 5650
CTSH 5655
FBXL5 5669
SLCO4C1 5675
ATP6V0E2 5683
LBP 5684
TRIM36 5698
IL10RB 5733
MASP2 5751
ACTR1B 5765
HLA-A 5777
SOD1 5779
CEP290 5787
RACGAP1 5789
EBI3 5791
AP1S1 5804
NUP93 5831
USP18 5875
HGSNAT 5921
KIF20A 5931
HLA-C 5936
MYD88 5939
LONRF1 5944
SKP2 5946
PSTPIP1 5948
IFIT3 5949
POLR2K 5962
ALDOC 5970
HERC6 5973
PSMD14 5974
TRIM32 5977
KIF2C 5981
NUP35 5982
FBXO17 5986
UNKL 5989
ATP8A1 5995
FLT3LG 6000
CISH 6003
CLEC2D 6035
KIF15 6037
FBXW4 6039
DYNLL2 6044
PROS1 6053
KIF4A 6056
DHX58 6062
ANAPC10 6071
CD4 6074
NUP107 6076
THEM4 6080
PLA2G6 6084
CD47 6101
CASP1 6109
CDC23 6113
FBXO41 6136
C6orf120 6141
AGA 6147
ANXA2 6155
TRIM56 6183
RNF41 6188
TRIM2 6197
UBA7 6211
CYFIP2 6224
LTA4H 6248
ANAPC7 6249
LRSAM1 6259
DNASE1L1 6262
NLRX1 6266
TRIM14 6269
TNFRSF11A 6300
RNF144B 6303
DET1 6311
KIF23 6313
ALAD 6318
ITGAL 6325
IFIT1 6374
ASB13 6386
TRIM22 6415
IL34 6416
BTN2A2 6418
CD68 6463
ITGB2 6494
DNM1 6505
IL1R1 6510
BPIFB1 6516
PTPN6 6557
HACE1 6570
STAT5B 6572
KIFAP3 6573
KIF11 6577
IFI35 6618
C6 6620
LAMA5 6638
MAPK3 6640
IFIH1 6646
TAB1 6687
FGG 6697
SYNGR1 6711
IFIT5 6717
C5AR1 6719
LRG1 6726
HP 6732
CDA 6735
TUBB4B 6758
KBTBD7 6772
KBTBD6 6796
NUP210 6802
PTK2B 6809
DZIP3 6813
PTPN18 6851
S100A1 6858
ALDH3B1 6860
CEBPD 6867
ICAM2 6868
SLC44A2 6879
TRIM45 6884
CFI 6891
BTN3A3 6893
PYCARD 6900
VTN 6910
MBL2 6911
DSN1 6916
TRAIP 6925
KIF22 6933
RAB37 6989
CD14 6998
RORC 7056
A1BG 7060
NUP37 7100
LMNB1 7101
IL1RN 7124
BTN3A1 7132
UBE2C 7137
BTN3A2 7149
NHLRC3 7191
C1R 7201
SLA2 7214
C5 7218
FGB 7226
NEDD4L 7233
C8A 7235
PLA2G2A 7254
GCA 7258
TKFC 7267
FBXL16 7269
UBE2L6 7272
C4B 7286
PLD1 7290
CDH1 7296
POLR3GL 7315
RNF125 7321
JAK3 7326
SERPINA3 7328
LEAP2 7329
FGA 7336
SOD2 7342
C8B 7343
C4A 7346
CFB 7350
CSF3R 7351
C3 7357
IL21R 7359
C1S 7360
SOCS3 7374
MUC5B 7378
TXNIP 7384
SERPING1 7387



SARS-CoV Infections

SARS-CoV Infections
1021
set SARS-CoV Infections
setSize 144
pANOVA 1.05e-10
s.dist -0.312
p.adjustANOVA 4.26e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
CANX -7092
MAGT1 -7045
MAP1LC3B -7040
RPN1 -7013
CTSL -6951
ATP1B3 -6941
ST3GAL4 -6801
STT3A -6796
ATP1A1 -6777
ST6GALNAC4 -6726
VCP -6720
FURIN -6683
DDX5 -6665
ATP1B1 -6624
CHMP4C -6557
VHL -6491
KEAP1 -6482
BRD4 -6479
DDOST -6429
MGAT1 -6401

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CANX -7092
MAGT1 -7045
MAP1LC3B -7040
RPN1 -7013
CTSL -6951
ATP1B3 -6941
ST3GAL4 -6801
STT3A -6796
ATP1A1 -6777
ST6GALNAC4 -6726
VCP -6720
FURIN -6683
DDX5 -6665
ATP1B1 -6624
CHMP4C -6557
VHL -6491
KEAP1 -6482
BRD4 -6479
DDOST -6429
MGAT1 -6401
BRMS1 -6309
UVRAG -6290
FNTA -6282
MGAT4B -6279
DAD1 -6240
RPN2 -6193
PRKCSH -5934
ST3GAL1 -5905
FXYD2 -5865
MGAT5 -5854
FKBP4 -5807
MTA2 -5619
EDEM2 -5520
CSNK1A1 -5349
SAP30 -5230
PIK3C3 -5220
FKBP1A -5189
TBK1 -5169
FUT8 -5134
GSK3B -5101
UBA52 -5068
CHMP4B -5021
MGAT4A -5018
JAK1 -4963
IL6R -4943
CHD4 -4830
AP2M1 -4603
MBD3 -4543
ST3GAL2 -4518
VEGFA -4456
HSP90AB1 -4426
PRMT1 -4281
UBB -4263
ITGB1 -4145
GATAD2A -4108
NR3C1 -4005
SAP30L -3887
PARP16 -3842
RBX1 -3714
ATP1B2 -3692
GSK3A -3684
ROCK1 -3594
MAN1B1 -3561
AP2A2 -3499
RCOR1 -3493
SAP18 -3349
MGAT2 -3327
RBBP4 -3297
HMG20B -3184
CUL3 -3056
AP2S1 -2922
BECN1 -2900
RIPK1 -2886
FXYD1 -2847
RPS27A -2773
ROCK2 -2772
JAK2 -2719
HDAC1 -2676
FNTB -2551
TLR9 -2371
IFNAR2 -2313
SUDS3 -2287
MOGS -2275
NFE2L2 -2108
CRBN -1928
SRPK2 -1905
AP2A1 -1902
ST6GAL1 -1828
IMPDH1 -1807
ATP1A3 -1706
PARP6 -1567
CHD3 -1321
UBE2I -1318
TUSC3 -1219
GATAD2B -1092
CHMP2A -1088
PHF21A -1078
MAN2A1 -1040
HSP90AA1 -1030
CHMP2B -878
GALNT1 -816
REST -593
HDAC2 -338
ARID4A -156
STAT2 76
ATP1A4 412
PARP4 462
RB1 470
ARID4B 480
SIGMAR1 753
UBC 779
CHMP4A 909
IFNGR2 997
PIK3R4 1132
CHMP3 1229
TMPRSS2 1456
IFNGR1 1624
MGAT4C 1714
MTA1 1810
AP2B1 2029
CYSLTR1 2493
COMT 2597
CHMP7 2690
ACE2 2757
GANAB 2813
SRPK1 3007
PARP8 3263
SUMO1 3308
PTGES3 3734
IFNAR1 4161
KDM1A 4224
ZCRB1 4731
IMPDH2 4910
TYK2 5066
TUBB 5125
RBBP7 5134
PARP14 5386
PARP10 5859
CHMP6 5904
ST3GAL3 5918
MTA3 6411
IL1R1 6510
PARP9 6988
JAK3 7326



Unfolded Protein Response (UPR)

Unfolded Protein Response (UPR)
1318
set Unfolded Protein Response (UPR)
setSize 89
pANOVA 1.43e-10
s.dist -0.393
p.adjustANOVA 5.62e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
HSPA5 -7144
CALR -7142
DNAJB11 -7141
HYOU1 -7140
HERPUD1 -7137
DNAJC3 -7131
HSP90B1 -7129
DNAJB9 -7125
SYVN1 -7108
PDIA6 -7106
EDEM1 -7103
WFS1 -7096
GFPT1 -7051
DDIT3 -7047
EIF2AK3 -7028
MYDGF -6976
SERP1 -6964
ATF6 -6949
WIPI1 -6942
SHC1 -6910

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
HSPA5 -7144
CALR -7142
DNAJB11 -7141
HYOU1 -7140
HERPUD1 -7137
DNAJC3 -7131
HSP90B1 -7129
DNAJB9 -7125
SYVN1 -7108
PDIA6 -7106
EDEM1 -7103
WFS1 -7096
GFPT1 -7051
DDIT3 -7047
EIF2AK3 -7028
MYDGF -6976
SERP1 -6964
ATF6 -6949
WIPI1 -6942
SHC1 -6910
ATP6V0D1 -6908
SSR1 -6907
FKBP14 -6896
SRPRB -6893
ERN1 -6872
CREB3L2 -6832
TSPYL2 -6784
HDGF -6715
EXOSC6 -6503
TATDN2 -6467
TPP1 -6407
TLN1 -6146
CXXC1 -6033
CEBPG -5987
ADD1 -5966
MBTPS1 -5958
SEC31A -5766
ATF4 -5664
EIF2S1 -5190
PPP2R5B -5131
DCP2 -5125
SRPRA -4802
EXOSC5 -4766
CREBRF -4582
PARN -4578
CTDSP2 -4462
EIF2S2 -4458
IGFBP1 -3931
KLHDC3 -3802
LMNA -3717
GSK3A -3684
EIF2S3 -3669
CREB3 -3650
EXOSC3 -3453
ZBTB17 -3194
NFYA -2482
DCTN1 -1635
ARFGAP1 -1587
DIS3 -1573
CEBPB -1129
KHSRP -994
NFYC -690
YIF1A 195
EXOSC8 472
PDIA5 579
KDELR3 976
SULT1A3 1040
GOSR2 1238
PREB 1446
ATF3 2488
EXOSC4 3220
EXOSC9 3293
EXTL2 3353
EXOSC1 3486
EXTL3 3575
CXCL8 3625
MBTPS2 3687
EXOSC2 3779
ACADVL 4157
CUL7 4377
PLA2G4B 4716
NFYB 5091
EXOSC7 5196
CREB3L4 5920
XBP1 5937
CREB3L3 5999
ASNS 6208
DDX11 6254
EXTL1 6941



Major pathway of rRNA processing in the nucleolus and cytosol

Major pathway of rRNA processing in the nucleolus and cytosol
609
set Major pathway of rRNA processing in the nucleolus and cytosol
setSize 174
pANOVA 1.91e-10
s.dist -0.28
p.adjustANOVA 7.29e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL36AL -6981
MPHOSPH10 -6827
DDX49 -6809
EXOSC6 -6503
RRP36 -6354
RIOK3 -6332
UTP14C -6243
UTP4 -6111
UTP14A -5799
PNO1 -5758
CSNK1D -5722
LTV1 -5474
GNL3 -5332
RPL19 -5254
DHX37 -5250
NOP14 -5209
RPS7 -5138
RRP1 -5133
UBA52 -5068
RPL11 -5032

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL36AL -6981
MPHOSPH10 -6827
DDX49 -6809
EXOSC6 -6503
RRP36 -6354
RIOK3 -6332
UTP14C -6243
UTP4 -6111
UTP14A -5799
PNO1 -5758
CSNK1D -5722
LTV1 -5474
GNL3 -5332
RPL19 -5254
DHX37 -5250
NOP14 -5209
RPS7 -5138
RRP1 -5133
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
NOL9 -4954
IMP4 -4940
RPS5 -4778
BMS1 -4769
EXOSC5 -4766
RPS11 -4702
RPS19 -4661
RPS28 -4652
IMP3 -4633
UTP18 -4476
RPLP1 -4391
BOP1 -4381
RPS12 -4367
RPL27A -4297
RPLP0 -4290
TEX10 -4283
WDR43 -4193
RPL35A -4159
RPL30 -4081
DDX47 -4068
RPS9 -4028
RIOK2 -4018
RPL18 -3961
DDX52 -3894
RPL26L1 -3873
RPS29 -3844
RPL6 -3843
NOL12 -3773
NOB1 -3772
ISG20L2 -3623
EBNA1BP2 -3613
RPL28 -3546
RPSA -3520
PES1 -3505
RPL8 -3467
RPS4X -3464
RPS2 -3462
EXOSC3 -3453
RPL29 -3450
RPL32 -3448
RPL36 -3432
XRN2 -3427
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
RPS15A -3019
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
PELP1 -2894
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
UTP20 -2811
RPS27A -2773
FCF1 -2713
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
BYSL -2637
RPL41 -2635
RRP9 -2591
RPS13 -2581
RPL4 -2563
UTP15 -2509
ERI1 -2490
RPS23 -2467
RPL37A -2451
RPL39 -2270
RPL18A -2240
RPL7A -2233
NIP7 -2165
RPS4Y1 -2120
RPL27 -2070
PWP2 -2005
RPL23 -1913
NCL -1840
UTP6 -1836
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
DIS3 -1573
NOC4L -1552
FBL -1548
SENP3 -1399
UTP11 -1337
HEATR1 -1324
RPL15 -1313
RPL3 -1165
NOP56 -1145
RPL17 -1119
RPS8 -1071
RPL12 -983
RCL1 -942
RPS25 -937
TSR1 -851
TBL3 -794
RPL13 -706
RPL5 -495
EXOSC10 -341
DDX21 -256
RPL22L1 -214
RPS3A -179
RPS27 -152
SNU13 -129
RPL9 261
RPL31 330
RPS26 419
EXOSC8 472
RBM28 771
KRR1 924
RPP14 1309
RPL21 1385
RPP30 1439
RPP38 1564
RPP40 1770
NOL6 1999
RRP7A 2006
FTSJ3 2052
WDR18 2127
RPL22 2142
RIOK1 2711
RPL36A 2875
EXOSC4 3220
CSNK1E 3247
EXOSC9 3293
PDCD11 3334
C1D 3482
EXOSC1 3486
WDR75 3573
EXOSC2 3779
WDR12 3814
NOL11 4020
UTP3 4280
DCAF13 4652
WDR46 4709
EXOSC7 5196
NOP58 5612
MPHOSPH6 5619
WDR3 5692
WDR36 5735
LAS1L 7022
EMG1 7347



Eukaryotic Translation Termination

Eukaryotic Translation Termination
338
set Eukaryotic Translation Termination
setSize 89
pANOVA 2.8e-10
s.dist -0.387
p.adjustANOVA 1.04e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL36AL -6981
ETF1 -6952
GSPT1 -6825
RPL19 -5254
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
RPS11 -4702
RPS19 -4661
RPS28 -4652
RPLP1 -4391
RPS12 -4367
RPL27A -4297
RPLP0 -4290
RPL35A -4159

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL36AL -6981
ETF1 -6952
GSPT1 -6825
RPL19 -5254
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
RPS11 -4702
RPS19 -4661
RPS28 -4652
RPLP1 -4391
RPS12 -4367
RPL27A -4297
RPLP0 -4290
RPL35A -4159
RPL30 -4081
RPS9 -4028
RPL18 -3961
RPL26L1 -3873
TRMT112 -3869
RPS29 -3844
RPL6 -3843
RPL28 -3546
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
RPS15A -3019
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
RPS27A -2773
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RPS13 -2581
RPL4 -2563
RPS23 -2467
RPL37A -2451
RPL39 -2270
RPL18A -2240
RPL7A -2233
RPS4Y1 -2120
RPL27 -2070
RPL23 -1913
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
RPL15 -1313
RPL3 -1165
RPL17 -1119
RPS8 -1071
RPL12 -983
RPS25 -937
RPL13 -706
RPL5 -495
RPL22L1 -214
RPS3A -179
RPS27 -152
RPL9 261
RPL31 330
RPS26 419
RPL21 1385
RPL22 2142
RPL36A 2875
APEH 4698
N6AMT1 7144



Vesicle-mediated transport

Vesicle-mediated transport
1327
set Vesicle-mediated transport
setSize 555
pANOVA 7.17e-10
s.dist -0.154
p.adjustANOVA 2.6e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
CALR -7142
HYOU1 -7140
SEC24D -7134
HSP90B1 -7129
RABGEF1 -7111
TMED2 -7071
MCFD2 -7065
ARRB1 -7062
MIA3 -7049
USP6NL -7041
MAP1LC3B -7040
AAK1 -7032
ANKRD27 -6996
RHOQ -6969
TMED7 -6933
VTI1A -6899
SEC24A -6839
GNS -6813
SEC13 -6812
ANK2 -6778

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CALR -7142
HYOU1 -7140
SEC24D -7134
HSP90B1 -7129
RABGEF1 -7111
TMED2 -7071
MCFD2 -7065
ARRB1 -7062
MIA3 -7049
USP6NL -7041
MAP1LC3B -7040
AAK1 -7032
ANKRD27 -6996
RHOQ -6969
TMED7 -6933
VTI1A -6899
SEC24A -6839
GNS -6813
SEC13 -6812
ANK2 -6778
TMEM115 -6764
RAB43 -6699
FTL -6697
SNX2 -6677
RHOBTB3 -6640
TFRC -6637
KIF5A -6634
TBC1D4 -6633
GAPVD1 -6615
SURF4 -6593
TRAPPC10 -6585
MON1B -6563
LMAN2 -6558
CHMP4C -6557
RALA -6548
WASL -6543
IGF2R -6540
HPS1 -6536
DNM2 -6535
COPB2 -6532
HSPH1 -6524
CD55 -6517
PPP6R1 -6511
ARCN1 -6505
TMED9 -6502
APP -6492
MAN1A2 -6460
CLTA -6439
M6PR -6416
SLC2A8 -6375
FNBP1 -6371
KIF3B -6315
TBC1D10B -6270
SEC24C -6236
CLTC -6220
TBC1D20 -6203
RAB3IL1 -6158
GGA2 -6138
REPS2 -6121
TMED10 -6116
ARPC4 -6094
CLTB -6064
MASP1 -6062
ARF1 -6021
AMBP -6015
RAB9A -6014
COLEC11 -5996
SEC16A -5971
COPE -5961
COG3 -5948
NAPA -5921
KDELR2 -5893
KIF2A -5815
ARF4 -5812
RAB7A -5810
SYS1 -5789
SEC31A -5766
GOLIM4 -5729
CSNK1D -5722
CBL -5708
ACBD3 -5703
SNAP23 -5681
OPTN -5656
TBC1D17 -5587
CYTH2 -5571
MADD -5505
SEC24B -5475
KIF16B -5457
KIF5B -5426
GOLGA5 -5424
FTH1 -5419
RAB5A -5408
PLIN3 -5406
ARF6 -5404
TXNDC5 -5385
EGFR -5383
CLINT1 -5368
TFG -5336
GOLGA2 -5310
STX5 -5300
ACTR3 -5296
KIF13B -5291
RAB32 -5287
RAB35 -5270
PPP6C -5241
TMF1 -5205
ACTR1A -5162
COPS2 -5161
TBC1D16 -5152
RAB3GAP1 -5143
COPG1 -5135
CYTH1 -5123
KDELR1 -5094
VAMP2 -5088
UBA52 -5068
ULK1 -5025
TSC1 -5024
CHMP4B -5021
GBF1 -4981
POLG -4973
VAMP8 -4969
SPTBN1 -4901
YKT6 -4899
COPS8 -4894
RAB31 -4876
CAPZA1 -4855
AREG -4847
NSF -4839
ARFGAP3 -4817
TJP1 -4801
SH3D19 -4772
MYH9 -4726
YIPF6 -4714
VPS37B -4696
ANK1 -4656
HSPA8 -4654
RABEP1 -4653
GOLGA4 -4624
VPS37C -4620
COPS3 -4618
AP2M1 -4603
ARL1 -4579
TRAPPC2L -4576
VPS53 -4557
NAA35 -4552
TGFA -4511
CYTH3 -4502
AGPAT3 -4469
CTSC -4446
HBEGF -4402
TRAPPC12 -4380
TBC1D25 -4373
VPS51 -4345
VPS45 -4271
GAK -4264
UBB -4263
COG2 -4254
HGS -4210
AP1S2 -4204
SH3GL1 -4200
RAB3IP -4190
VPS37A -4187
SFN -4169
AP3S1 -4104
COPB1 -4098
TMED3 -4057
ZW10 -4054
DNAJC6 -4039
TRAPPC3 -4032
GCC1 -4030
TRAPPC8 -4019
DENND5B -4010
COG5 -3964
KIF9 -3960
COPA -3958
DCTN2 -3957
SYNJ1 -3952
SCARB1 -3949
DNASE2 -3925
EXOC3 -3898
DYNC1LI2 -3897
NAPG -3872
SNAPIN -3828
NAA30 -3779
AGFG1 -3713
APOE -3670
TBC1D15 -3653
KIF21A -3640
DCTN5 -3634
MVB12B -3629
DYNC1H1 -3614
PACSIN2 -3606
YWHAH -3511
USO1 -3509
GPS1 -3506
MYO5A -3500
AP2A2 -3499
GOLGB1 -3498
RAB1B -3479
LMAN1 -3431
LMAN2L -3429
GRK3 -3418
DENND1A -3391
SBF1 -3389
KLC2 -3375
GABARAP -3322
RAB1A -3307
SYT11 -3281
ARRB2 -3248
CD59 -3245
PIP5K1C -3229
KIFC2 -3159
RALGAPA2 -3147
RAB5C -3129
LNPEP -3128
DENND5A -3083
TBC1D2 -3081
COPS6 -3063
PRKAA2 -3053
SCARB2 -3052
GRB2 -3047
COPS5 -3031
HBA1 -3024
RAB33B -2981
SAR1B -2973
BLOC1S3 -2972
APOB -2964
AKT1 -2958
AP2S1 -2922
VPS54 -2824
VAMP7 -2787
DYNC1I2 -2780
RPS27A -2773
TOR1A -2741
SEC23A -2717
LRP1 -2699
RIC1 -2565
GABARAPL2 -2535
DYNC1LI1 -2519
PUM1 -2507
TSC2 -2462
ARF3 -2430
ARFIP2 -2367
MAN2A2 -2336
RAB8A -2247
MON1A -2216
ARPC2 -2209
KIF1C -2167
RAB4A -2148
TSG101 -2130
TGOLN2 -2105
TOR1B -2030
GDI2 -2026
CNIH3 -1958
AKT2 -1946
DCTN4 -1937
AP1G1 -1916
TBC1D10A -1914
AP2A1 -1902
UBAP1 -1894
RAB39B -1774
PRKAB2 -1763
DENND4C -1727
CHMP5 -1722
SEC22C -1684
CUX1 -1665
DCTN1 -1635
BIN1 -1622
SYNJ2 -1613
ARFGAP1 -1587
CCZ1 -1551
CAPZA2 -1549
ARPC5 -1511
STX18 -1499
DTNBP1 -1483
AP4E1 -1454
RALGAPB -1446
SNX9 -1443
BICD2 -1420
KIF26B -1395
NAA38 -1234
MYO1C -1212
SNF8 -1198
SBF2 -1186
CAPZB -1169
CHMP2A -1088
MAN2A1 -1040
HSP90AA1 -1030
MAN1A1 -1021
YWHAG -1018
TRIP11 -990
FCHO2 -984
VPS4B -934
SH3KBP1 -917
BLOC1S1 -915
DVL2 -905
RGP1 -894
YWHAZ -885
CHMP2B -878
RAB11B -876
COPS7B -839
GALNT1 -816
EXOC2 -747
AP1S3 -739
EPN1 -737
SNAP29 -703
VAMP3 -698
PRKAB1 -680
KIFC1 -657
CALM1 -655
CCZ1B -629
PPP6R3 -623
GCC2 -597
ITSN2 -546
AP4B1 -526
STX4 -491
PAFAH1B2 -471
NAPB -419
RAB18 -372
DCTN6 -318
STX6 -263
PIK3C2A -176
GDI1 -158
PAFAH1B1 -118
EXOC8 -92
SCARF1 -89
GOLGA1 -86
COPS4 -28
AP3B1 13
STON2 17
RAC1 44
RABGAP1 98
TBC1D3 112
YWHAE 129
ITSN1 159
CNIH1 212
TRAPPC5 239
TBC1D14 280
RAB30 288
PAFAH1B3 289
ANK3 303
EXOC5 337
PRKAG2 375
SEC23IP 390
BET1 457
SCFD1 485
SORT1 504
COLEC12 522
YWHAQ 542
NEDD8 580
GOSR1 621
FCHO1 665
RAB3GAP2 730
F8 735
UBC 779
COPZ1 782
VPS37D 809
F5 831
SEC22B 859
CHMP4A 909
AP1M2 914
GJC1 937
AP1B1 940
RAB12 950
KDELR3 976
CTTN 982
SLC2A4 1030
EXOC4 1053
DENND4B 1143
COL1A1 1188
KIF27 1204
GRK2 1205
FNBP1L 1226
TPD52 1228
CHMP3 1229
LDLRAP1 1234
GOSR2 1238
HIP1R 1249
EPS15 1254
ARFGAP2 1283
RAB6A 1296
DAB2 1366
RAB6B 1396
ACTR2 1435
PREB 1446
DCTN3 1457
RIN3 1485
KIF6 1507
SPARC 1607
RAB10 1625
VTA1 1653
NECAP2 1733
CHML 1746
TRAPPC4 1781
DENND1B 1843
KIF3C 1853
TRAPPC13 1878
GORASP1 1903
COG4 1972
PICALM 2021
AP2B1 2029
YWHAB 2082
DENND4A 2123
SNX5 2153
AGTR1 2260
KIF5C 2266
TBC1D13 2281
ALS2 2318
STX10 2338
VPS4A 2374
HPS4 2384
SPTAN1 2385
STON1 2425
NBAS 2435
UBQLN2 2456
VPS36 2474
EXOC6 2506
DYNLL1 2509
BNIP1 2517
GGA1 2520
BLOC1S4 2530
TRAPPC6B 2584
STX17 2586
STX16 2644
MYO6 2665
CHMP7 2690
RAB21 2694
KIF1B 2782
USE1 2847
VPS25 2895
RAB5B 2913
KIF21B 2922
AP1M1 2926
RINT1 2930
RAB27A 3011
ARPC1A 3022
MAN1C1 3072
STAM2 3080
TRAPPC1 3089
REPS1 3092
ALB 3096
DENND2A 3098
KLC3 3105
AP4M1 3223
VAMP4 3226
TPD52L1 3255
AP1G2 3257
COG6 3264
KIF3A 3299
SEC22A 3312
STAB1 3437
EREG 3467
EPS15L1 3478
BET1L 3487
EXOC7 3531
TRAPPC2 3547
RAB14 3647
RAB13 3724
ST5 3764
BLOC1S6 3795
ARPC3 3797
PRKAG1 3836
SPTBN2 3883
STXBP3 3896
KLC4 3897
TBC1D24 3937
TBC1D7 3939
DENND2C 3943
SRC 3962
SERPINA1 4014
SCOC 4060
TBC1D1 4089
RIN1 4122
VPS52 4124
ANKRD28 4146
VPS28 4152
GGA3 4199
RAB3A 4309
TRIP10 4417
RAB11A 4527
COG1 4586
KLC1 4611
RAB8B 4676
ASPSCR1 4685
ARF5 4743
COG7 4792
DENND6B 4871
KIF18B 4885
APOL1 4896
RAB36 4950
AP4S1 4973
TRAPPC9 5033
SYTL1 5101
STAM 5109
RINL 5161
LDLR 5216
KIF18A 5234
CD36 5264
SNX18 5273
NECAP1 5336
PACSIN3 5360
COL7A1 5362
TBC1D10C 5382
CHM 5425
CENPE 5538
ACTR10 5570
MVB12A 5589
BICD1 5599
COPS7A 5653
DENND1C 5679
DENND6A 5729
TBC1D8B 5738
RACGAP1 5789
AP1S1 5804
TF 5850
HPX 5880
CHMP6 5904
KIF20A 5931
KIF2C 5981
KIF15 6037
DYNLL2 6044
KIF4A 6056
CD4 6074
PLA2G6 6084
RIN2 6115
UBQLN1 6140
COPG2 6142
KIF12 6210
TRAPPC11 6281
GJC2 6283
ARFRP1 6299
EXOC1 6302
KIF23 6313
RABEPK 6388
CLTCL1 6404
DNM1 6505
FZD4 6534
HPR 6549
KIFAP3 6573
KIF11 6577
GALNT2 6578
DENND3 6588
C2CD5 6602
GJB1 6678
KIF20B 6682
HP 6732
SEC16B 6744
COG8 6745
OCRL 6835
EPN2 6839
CPD 6859
KIF22 6933
APOA1 6993
TRAPPC6A 7244
HIP1 7319



Signaling by Receptor Tyrosine Kinases

Signaling by Receptor Tyrosine Kinases
1146
set Signaling by Receptor Tyrosine Kinases
setSize 405
pANOVA 7.81e-10
s.dist -0.179
p.adjustANOVA 2.76e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
ATP6V0B -7064
PGF -7053
SHB -7035
ATP6V0A1 -6979
BCAR1 -6926
ATP6V1D -6922
SHC1 -6910
ATP6V0D1 -6908
ATP6V0A2 -6880
MET -6878
RANBP9 -6871
VGF -6864
HNRNPM -6829
PDGFRB -6820
TRIB3 -6798
PTPN3 -6738
HNRNPF -6735
FURIN -6683
FOSL1 -6672
ATP6V0E1 -6622

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ATP6V0B -7064
PGF -7053
SHB -7035
ATP6V0A1 -6979
BCAR1 -6926
ATP6V1D -6922
SHC1 -6910
ATP6V0D1 -6908
ATP6V0A2 -6880
MET -6878
RANBP9 -6871
VGF -6864
HNRNPM -6829
PDGFRB -6820
TRIB3 -6798
PTPN3 -6738
HNRNPF -6735
FURIN -6683
FOSL1 -6672
ATP6V0E1 -6622
RAPGEF1 -6586
PRKCZ -6584
VEGFB -6562
RALA -6548
DUSP3 -6541
DNM2 -6535
EP300 -6470
MAPKAPK2 -6461
CLTA -6439
NAB2 -6372
LRIG1 -6280
ATP6V1E1 -6271
LCK -6250
ATP6AP1 -6235
CLTC -6220
ITGA2 -6205
PTPRK -6199
FGFR1 -6191
ATF2 -6175
PTPRJ -6103
FOSB -6091
ITCH -6089
ITPR3 -6088
MAP2K2 -6087
ATP6V0C -6086
KIDINS220 -6056
PTBP1 -6035
MEF2D -5995
RRAD -5988
DUSP4 -5977
MAPKAP1 -5936
ATP6V1C2 -5929
SIN3A -5884
SPP1 -5872
MEMO1 -5843
ADAM17 -5836
DIAPH1 -5806
MAPKAPK3 -5773
ELK1 -5733
WASF1 -5712
CBL -5708
STAT1 -5668
CRK -5650
PRKCD -5638
ATP6V1B2 -5574
CTNNA1 -5558
HRAS -5543
MAPK12 -5538
PRKCE -5510
GRB10 -5504
SHC2 -5479
POLR2L -5471
SOCS6 -5467
IRS2 -5461
NCF2 -5438
BRK1 -5431
ARF6 -5404
EGFR -5383
ATP6V1G1 -5352
PTPN12 -5326
LAMA3 -5316
NRP2 -5313
PDE3B -5303
RIT1 -5298
RHOA -5294
POLR2F -5283
PIK3C3 -5220
CDC37 -5178
FOS -5174
PPP2CA -5168
MXD4 -5116
INSR -5097
AAMP -5076
PDGFC -5072
UBA52 -5068
MAPK1 -5066
PAK2 -4957
ATP6V1C1 -4946
PSEN1 -4938
ATF1 -4925
NOS3 -4903
AREG -4847
CHD4 -4830
SH2B3 -4752
BRAF -4749
PPP2R1A -4744
MST1 -4720
POLR2E -4667
VAV3 -4642
AP2M1 -4603
PPP2CB -4523
TGFA -4511
ABI1 -4478
VEGFA -4456
TIAL1 -4432
ATP6V1H -4423
HBEGF -4402
MAPK7 -4382
PIK3R1 -4376
NCOR1 -4374
PTK2 -4346
ITPR1 -4321
ITGAV -4312
UBB -4263
HGS -4210
SH3GL1 -4200
HIF1A -4165
ITGB1 -4145
GAB2 -4127
MAP2K1 -4120
CSK -4113
FGF17 -4015
GRB7 -4006
SPINT1 -3991
EGR3 -3972
NCK2 -3916
TNS3 -3893
TAB2 -3878
DUSP7 -3870
RPS6KA1 -3857
PTPN2 -3809
KLB -3807
FRS2 -3790
SHC3 -3782
ATP6V1A -3777
FGFRL1 -3751
TNS4 -3726
POLR2B -3699
MTOR -3683
APOE -3670
ROCK1 -3594
POLR2H -3593
JUNB -3526
AP2A2 -3499
GRAP -3478
POLR2C -3425
DUSP6 -3376
WASF2 -3366
HSPB1 -3343
MEF2A -3308
GALNT3 -3227
EGR2 -3207
TCF12 -3164
SPHK1 -3142
GTF2F1 -3103
SRF -3090
ANOS1 -3087
GRB2 -3047
LYN -3038
RPS6KA3 -3030
AKT1 -2958
AP2S1 -2922
ARHGEF7 -2913
SPRED2 -2862
USP8 -2820
PIK3CA -2813
FGFR4 -2795
NCKAP1 -2788
ELMO1 -2779
RPS27A -2773
ROCK2 -2772
IGF1R -2746
JAK2 -2719
HDAC1 -2676
ADAM10 -2671
PDGFA -2660
AXL -2605
PIK3CB -2588
ARC -2587
SPRED1 -2574
PSEN2 -2559
MAP2K5 -2441
TLR9 -2371
ESRP2 -2361
MKNK1 -2340
PSENEN -2327
ERBIN -2316
NELFB -2298
PIK3R3 -2279
CDC42 -2172
NCBP1 -2151
RAB4A -2148
PPP2R5D -2117
PRR5 -2094
RICTOR -2076
KRAS -2044
SPRY2 -1990
AKT2 -1946
SPRY1 -1918
AP2A1 -1902
MAPK13 -1875
HNRNPA1 -1795
ITGA3 -1662
STAT6 -1541
WWOX -1477
EGR1 -1475
PRKACB -1429
ADAP1 -1403
PIK3R2 -1355
CDK5 -1352
RANBP10 -1342
YES1 -1340
LAMC1 -1300
VRK3 -1278
CUL5 -1229
ABI2 -1197
FGFR3 -1195
RPS6KA2 -1149
HSP90AA1 -1030
MUC20 -1019
NCKAP1L -972
SOS1 -950
SH3KBP1 -917
ATP6V1F -868
PTPN11 -867
WWP1 -779
EPN1 -737
LAMB3 -673
CALM1 -655
BAIAP2 -637
SPINT2 -632
POLR2J -603
REST -593
NCSTN -554
ATP6V1E2 -534
GABRG3 -451
HDAC2 -338
ID2 -282
LAMC2 -228
CDK5R1 -157
HDAC3 38
RAC1 44
KITLG 92
TCIRG1 180
NEDD4 196
MAPK11 251
RALB 270
RAP1A 309
FGF5 342
PTPRS 397
PDPK1 399
CREB1 474
LAMB2 495
CRKL 524
APH1A 619
ATP6V1G2 690
LYL1 726
ATP6V0D2 747
NAB1 765
UBC 779
LAMA4 790
MATK 851
SGK1 865
ELMO2 942
PAK1 1031
PIK3R4 1132
SH2B2 1149
GABRB3 1163
LAMC3 1169
EPS15 1254
LAMA1 1285
RBFOX2 1286
GRIN2B 1330
NRP1 1353
NCK1 1525
GAB1 1575
SPARC 1607
F3 1642
PRKACA 1736
MLST8 1875
MYC 1892
FYN 1937
CYFIP1 1939
POLR2G 2003
AP2B1 2029
YWHAB 2082
COL6A3 2085
FGF23 2097
FRS3 2112
FLT4 2167
YAP1 2171
CYBA 2202
ID3 2220
ITPR2 2257
MAPK14 2269
NRAS 2310
JUP 2314
POLR2D 2418
PRKCA 2439
PLCG1 2511
THBS2 2512
PXN 2548
GFAP 2552
RASA1 2559
WASF3 2619
STMN1 2680
POLR2A 2705
PAG1 2774
VAV2 2817
GABRG2 2849
STAM2 3080
RPS6KA5 3086
HNRNPH1 3111
RAB4B 3174
COL6A2 3222
CTNNB1 3272
PTK6 3304
STUB1 3373
PCSK5 3449
EREG 3467
EPS15L1 3478
IRS1 3502
FLRT1 3504
DOCK1 3540
RAP1B 3577
PTPN1 3622
LAMB1 3783
DOCK7 3822
SRC 3962
FLRT2 3988
GGA3 4199
ERBB3 4249
STAT3 4253
CHEK1 4365
FER 4431
PTPRU 4441
THBS3 4450
TIAM1 4452
ID1 4484
ATP6V1B1 4549
GTF2F2 4556
JUND 4563
POLR2I 4594
PPP2R1B 4614
MDK 4615
RALGDS 4617
TPH1 4694
BAX 4757
PLAT 4797
AHCYL1 4874
SOCS1 5053
DLG4 5108
STAM 5109
MST1R 5156
STAT5A 5288
PCSK6 5326
ADORA2A 5330
TRIB1 5404
FES 5506
ERBB2 5534
ATP6V0E2 5683
SH2D2A 5820
TF 5850
POLR2K 5962
THBS1 5988
FLT3LG 6000
THEM4 6080
APH1B 6168
RNF41 6188
CYFIP2 6224
TIA1 6310
DNM1 6505
PTPN6 6557
STAT5B 6572
DNAL4 6609
LAMA5 6638
MAPK3 6640
COL4A5 6694
HGFAC 6708
FGFBP3 6730
PTK2B 6809
FGFR2 6811
HPN 6820
NCBP2 6823
PTPN18 6851
PDGFB 6920
CTNND1 7129
COL9A3 7151
THBS4 7170
FLRT3 7184
COL6A1 7322
JAK3 7326
COL9A2 7348
IGF2 7375
PLG 7380



Membrane Trafficking

Membrane Trafficking
614
set Membrane Trafficking
setSize 531
pANOVA 9.78e-10
s.dist -0.156
p.adjustANOVA 3.37e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
SEC24D -7134
RABGEF1 -7111
TMED2 -7071
MCFD2 -7065
ARRB1 -7062
MIA3 -7049
USP6NL -7041
MAP1LC3B -7040
AAK1 -7032
ANKRD27 -6996
RHOQ -6969
TMED7 -6933
VTI1A -6899
SEC24A -6839
GNS -6813
SEC13 -6812
ANK2 -6778
TMEM115 -6764
RAB43 -6699
FTL -6697

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SEC24D -7134
RABGEF1 -7111
TMED2 -7071
MCFD2 -7065
ARRB1 -7062
MIA3 -7049
USP6NL -7041
MAP1LC3B -7040
AAK1 -7032
ANKRD27 -6996
RHOQ -6969
TMED7 -6933
VTI1A -6899
SEC24A -6839
GNS -6813
SEC13 -6812
ANK2 -6778
TMEM115 -6764
RAB43 -6699
FTL -6697
SNX2 -6677
RHOBTB3 -6640
TFRC -6637
KIF5A -6634
TBC1D4 -6633
GAPVD1 -6615
SURF4 -6593
TRAPPC10 -6585
MON1B -6563
LMAN2 -6558
CHMP4C -6557
RALA -6548
WASL -6543
IGF2R -6540
HPS1 -6536
DNM2 -6535
COPB2 -6532
CD55 -6517
PPP6R1 -6511
ARCN1 -6505
TMED9 -6502
APP -6492
MAN1A2 -6460
CLTA -6439
M6PR -6416
SLC2A8 -6375
FNBP1 -6371
KIF3B -6315
TBC1D10B -6270
SEC24C -6236
CLTC -6220
TBC1D20 -6203
RAB3IL1 -6158
GGA2 -6138
REPS2 -6121
TMED10 -6116
ARPC4 -6094
CLTB -6064
ARF1 -6021
RAB9A -6014
SEC16A -5971
COPE -5961
COG3 -5948
NAPA -5921
KDELR2 -5893
KIF2A -5815
ARF4 -5812
RAB7A -5810
SYS1 -5789
SEC31A -5766
GOLIM4 -5729
CSNK1D -5722
CBL -5708
ACBD3 -5703
SNAP23 -5681
OPTN -5656
TBC1D17 -5587
CYTH2 -5571
MADD -5505
SEC24B -5475
KIF16B -5457
KIF5B -5426
GOLGA5 -5424
FTH1 -5419
RAB5A -5408
PLIN3 -5406
ARF6 -5404
TXNDC5 -5385
EGFR -5383
CLINT1 -5368
TFG -5336
GOLGA2 -5310
STX5 -5300
ACTR3 -5296
KIF13B -5291
RAB32 -5287
RAB35 -5270
PPP6C -5241
TMF1 -5205
ACTR1A -5162
COPS2 -5161
TBC1D16 -5152
RAB3GAP1 -5143
COPG1 -5135
CYTH1 -5123
KDELR1 -5094
VAMP2 -5088
UBA52 -5068
ULK1 -5025
TSC1 -5024
CHMP4B -5021
GBF1 -4981
POLG -4973
VAMP8 -4969
SPTBN1 -4901
YKT6 -4899
COPS8 -4894
RAB31 -4876
CAPZA1 -4855
AREG -4847
NSF -4839
ARFGAP3 -4817
TJP1 -4801
SH3D19 -4772
MYH9 -4726
YIPF6 -4714
VPS37B -4696
ANK1 -4656
HSPA8 -4654
RABEP1 -4653
GOLGA4 -4624
VPS37C -4620
COPS3 -4618
AP2M1 -4603
ARL1 -4579
TRAPPC2L -4576
VPS53 -4557
NAA35 -4552
TGFA -4511
CYTH3 -4502
AGPAT3 -4469
CTSC -4446
HBEGF -4402
TRAPPC12 -4380
TBC1D25 -4373
VPS51 -4345
VPS45 -4271
GAK -4264
UBB -4263
COG2 -4254
HGS -4210
AP1S2 -4204
SH3GL1 -4200
RAB3IP -4190
VPS37A -4187
SFN -4169
AP3S1 -4104
COPB1 -4098
TMED3 -4057
ZW10 -4054
DNAJC6 -4039
TRAPPC3 -4032
GCC1 -4030
TRAPPC8 -4019
DENND5B -4010
COG5 -3964
KIF9 -3960
COPA -3958
DCTN2 -3957
SYNJ1 -3952
DNASE2 -3925
EXOC3 -3898
DYNC1LI2 -3897
NAPG -3872
SNAPIN -3828
NAA30 -3779
AGFG1 -3713
TBC1D15 -3653
KIF21A -3640
DCTN5 -3634
MVB12B -3629
DYNC1H1 -3614
PACSIN2 -3606
YWHAH -3511
USO1 -3509
GPS1 -3506
MYO5A -3500
AP2A2 -3499
GOLGB1 -3498
RAB1B -3479
LMAN1 -3431
LMAN2L -3429
GRK3 -3418
DENND1A -3391
SBF1 -3389
KLC2 -3375
GABARAP -3322
RAB1A -3307
SYT11 -3281
ARRB2 -3248
CD59 -3245
PIP5K1C -3229
KIFC2 -3159
RALGAPA2 -3147
RAB5C -3129
LNPEP -3128
DENND5A -3083
TBC1D2 -3081
COPS6 -3063
PRKAA2 -3053
SCARB2 -3052
GRB2 -3047
COPS5 -3031
RAB33B -2981
SAR1B -2973
BLOC1S3 -2972
APOB -2964
AKT1 -2958
AP2S1 -2922
VPS54 -2824
VAMP7 -2787
DYNC1I2 -2780
RPS27A -2773
TOR1A -2741
SEC23A -2717
RIC1 -2565
GABARAPL2 -2535
DYNC1LI1 -2519
PUM1 -2507
TSC2 -2462
ARF3 -2430
ARFIP2 -2367
MAN2A2 -2336
RAB8A -2247
MON1A -2216
ARPC2 -2209
KIF1C -2167
RAB4A -2148
TSG101 -2130
TGOLN2 -2105
TOR1B -2030
GDI2 -2026
CNIH3 -1958
AKT2 -1946
DCTN4 -1937
AP1G1 -1916
TBC1D10A -1914
AP2A1 -1902
UBAP1 -1894
RAB39B -1774
PRKAB2 -1763
DENND4C -1727
CHMP5 -1722
SEC22C -1684
CUX1 -1665
DCTN1 -1635
BIN1 -1622
SYNJ2 -1613
ARFGAP1 -1587
CCZ1 -1551
CAPZA2 -1549
ARPC5 -1511
STX18 -1499
DTNBP1 -1483
AP4E1 -1454
RALGAPB -1446
SNX9 -1443
BICD2 -1420
KIF26B -1395
NAA38 -1234
MYO1C -1212
SNF8 -1198
SBF2 -1186
CAPZB -1169
CHMP2A -1088
MAN2A1 -1040
MAN1A1 -1021
YWHAG -1018
TRIP11 -990
FCHO2 -984
VPS4B -934
SH3KBP1 -917
BLOC1S1 -915
DVL2 -905
RGP1 -894
YWHAZ -885
CHMP2B -878
RAB11B -876
COPS7B -839
GALNT1 -816
EXOC2 -747
AP1S3 -739
EPN1 -737
SNAP29 -703
VAMP3 -698
PRKAB1 -680
KIFC1 -657
CALM1 -655
CCZ1B -629
PPP6R3 -623
GCC2 -597
ITSN2 -546
AP4B1 -526
STX4 -491
PAFAH1B2 -471
NAPB -419
RAB18 -372
DCTN6 -318
STX6 -263
PIK3C2A -176
GDI1 -158
PAFAH1B1 -118
EXOC8 -92
GOLGA1 -86
COPS4 -28
AP3B1 13
STON2 17
RAC1 44
RABGAP1 98
TBC1D3 112
YWHAE 129
ITSN1 159
CNIH1 212
TRAPPC5 239
TBC1D14 280
RAB30 288
PAFAH1B3 289
ANK3 303
EXOC5 337
PRKAG2 375
SEC23IP 390
BET1 457
SCFD1 485
SORT1 504
YWHAQ 542
NEDD8 580
GOSR1 621
FCHO1 665
RAB3GAP2 730
F8 735
UBC 779
COPZ1 782
VPS37D 809
F5 831
SEC22B 859
CHMP4A 909
AP1M2 914
GJC1 937
AP1B1 940
RAB12 950
KDELR3 976
CTTN 982
SLC2A4 1030
EXOC4 1053
DENND4B 1143
KIF27 1204
GRK2 1205
FNBP1L 1226
TPD52 1228
CHMP3 1229
LDLRAP1 1234
GOSR2 1238
HIP1R 1249
EPS15 1254
ARFGAP2 1283
RAB6A 1296
DAB2 1366
RAB6B 1396
ACTR2 1435
PREB 1446
DCTN3 1457
RIN3 1485
KIF6 1507
RAB10 1625
VTA1 1653
NECAP2 1733
CHML 1746
TRAPPC4 1781
DENND1B 1843
KIF3C 1853
TRAPPC13 1878
GORASP1 1903
COG4 1972
PICALM 2021
AP2B1 2029
YWHAB 2082
DENND4A 2123
SNX5 2153
AGTR1 2260
KIF5C 2266
TBC1D13 2281
ALS2 2318
STX10 2338
VPS4A 2374
HPS4 2384
SPTAN1 2385
STON1 2425
NBAS 2435
UBQLN2 2456
VPS36 2474
EXOC6 2506
DYNLL1 2509
BNIP1 2517
GGA1 2520
BLOC1S4 2530
TRAPPC6B 2584
STX17 2586
STX16 2644
MYO6 2665
CHMP7 2690
RAB21 2694
KIF1B 2782
USE1 2847
VPS25 2895
RAB5B 2913
KIF21B 2922
AP1M1 2926
RINT1 2930
RAB27A 3011
ARPC1A 3022
MAN1C1 3072
STAM2 3080
TRAPPC1 3089
REPS1 3092
DENND2A 3098
KLC3 3105
AP4M1 3223
VAMP4 3226
TPD52L1 3255
AP1G2 3257
COG6 3264
KIF3A 3299
SEC22A 3312
EREG 3467
EPS15L1 3478
BET1L 3487
EXOC7 3531
TRAPPC2 3547
RAB14 3647
RAB13 3724
ST5 3764
BLOC1S6 3795
ARPC3 3797
PRKAG1 3836
SPTBN2 3883
STXBP3 3896
KLC4 3897
TBC1D24 3937
TBC1D7 3939
DENND2C 3943
SRC 3962
SERPINA1 4014
SCOC 4060
TBC1D1 4089
RIN1 4122
VPS52 4124
ANKRD28 4146
VPS28 4152
GGA3 4199
RAB3A 4309
TRIP10 4417
RAB11A 4527
COG1 4586
KLC1 4611
RAB8B 4676
ASPSCR1 4685
ARF5 4743
COG7 4792
DENND6B 4871
KIF18B 4885
RAB36 4950
AP4S1 4973
TRAPPC9 5033
SYTL1 5101
STAM 5109
RINL 5161
LDLR 5216
KIF18A 5234
SNX18 5273
NECAP1 5336
PACSIN3 5360
COL7A1 5362
TBC1D10C 5382
CHM 5425
CENPE 5538
ACTR10 5570
MVB12A 5589
BICD1 5599
COPS7A 5653
DENND1C 5679
DENND6A 5729
TBC1D8B 5738
RACGAP1 5789
AP1S1 5804
TF 5850
CHMP6 5904
KIF20A 5931
KIF2C 5981
KIF15 6037
DYNLL2 6044
KIF4A 6056
CD4 6074
PLA2G6 6084
RIN2 6115
UBQLN1 6140
COPG2 6142
KIF12 6210
TRAPPC11 6281
GJC2 6283
ARFRP1 6299
EXOC1 6302
KIF23 6313
RABEPK 6388
CLTCL1 6404
DNM1 6505
FZD4 6534
KIFAP3 6573
KIF11 6577
GALNT2 6578
DENND3 6588
C2CD5 6602
GJB1 6678
KIF20B 6682
SEC16B 6744
COG8 6745
OCRL 6835
EPN2 6839
CPD 6859
KIF22 6933
TRAPPC6A 7244
HIP1 7319



Selenocysteine synthesis

Selenocysteine synthesis
1057
set Selenocysteine synthesis
setSize 89
pANOVA 1e-09
s.dist -0.375
p.adjustANOVA 3.37e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL36AL -6981
SEPHS2 -6447
RPL19 -5254
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
RPS11 -4702
RPS19 -4661
RPS28 -4652
RPLP1 -4391
RPS12 -4367
RPL27A -4297
RPLP0 -4290
RPL35A -4159
RPL30 -4081

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL36AL -6981
SEPHS2 -6447
RPL19 -5254
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
RPS11 -4702
RPS19 -4661
RPS28 -4652
RPLP1 -4391
RPS12 -4367
RPL27A -4297
RPLP0 -4290
RPL35A -4159
RPL30 -4081
RPS9 -4028
RPL18 -3961
RPL26L1 -3873
RPS29 -3844
RPL6 -3843
RPL28 -3546
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
RPS15A -3019
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
RPS27A -2773
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RPS13 -2581
RPL4 -2563
RPS23 -2467
RPL37A -2451
RPL39 -2270
RPL18A -2240
RPL7A -2233
RPS4Y1 -2120
RPL27 -2070
RPL23 -1913
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
PSTK -1545
RPL15 -1313
RPL3 -1165
RPL17 -1119
RPS8 -1071
RPL12 -983
RPS25 -937
RPL13 -706
RPL5 -495
SECISBP2 -410
RPL22L1 -214
RPS3A -179
RPS27 -152
RPL9 261
RPL31 330
RPS26 419
RPL21 1385
RPL22 2142
RPL36A 2875
EEFSEC 3653
SEPSECS 6852



IRE1alpha activates chaperones

IRE1alpha activates chaperones
498
set IRE1alpha activates chaperones
setSize 50
pANOVA 2.24e-09
s.dist -0.489
p.adjustANOVA 7.35e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
HSPA5 -7144
DNAJB11 -7141
HYOU1 -7140
DNAJC3 -7131
DNAJB9 -7125
SYVN1 -7108
PDIA6 -7106
EDEM1 -7103
WFS1 -7096
GFPT1 -7051
MYDGF -6976
SERP1 -6964
WIPI1 -6942
SHC1 -6910
ATP6V0D1 -6908
SSR1 -6907
FKBP14 -6896
SRPRB -6893
ERN1 -6872
TSPYL2 -6784

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
HSPA5 -7144
DNAJB11 -7141
HYOU1 -7140
DNAJC3 -7131
DNAJB9 -7125
SYVN1 -7108
PDIA6 -7106
EDEM1 -7103
WFS1 -7096
GFPT1 -7051
MYDGF -6976
SERP1 -6964
WIPI1 -6942
SHC1 -6910
ATP6V0D1 -6908
SSR1 -6907
FKBP14 -6896
SRPRB -6893
ERN1 -6872
TSPYL2 -6784
HDGF -6715
TATDN2 -6467
TPP1 -6407
TLN1 -6146
CXXC1 -6033
ADD1 -5966
SEC31A -5766
PPP2R5B -5131
SRPRA -4802
CTDSP2 -4462
KLHDC3 -3802
LMNA -3717
GSK3A -3684
ZBTB17 -3194
DCTN1 -1635
ARFGAP1 -1587
YIF1A 195
PDIA5 579
KDELR3 976
SULT1A3 1040
GOSR2 1238
PREB 1446
EXTL2 3353
EXTL3 3575
ACADVL 4157
CUL7 4377
PLA2G4B 4716
XBP1 5937
DDX11 6254
EXTL1 6941



Transport to the Golgi and subsequent modification

Transport to the Golgi and subsequent modification
1306
set Transport to the Golgi and subsequent modification
setSize 146
pANOVA 2.45e-09
s.dist -0.286
p.adjustANOVA 7.84e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
SEC24D -7134
TMED2 -7071
MCFD2 -7065
MIA3 -7049
FUT3 -7001
TMED7 -6933
SEC24A -6839
SEC13 -6812
ST3GAL4 -6801
ANK2 -6778
TMEM115 -6764
TRAPPC10 -6585
LMAN2 -6558
COPB2 -6532
CD55 -6517
PPP6R1 -6511
ARCN1 -6505
TMED9 -6502
MAN1A2 -6460
MGAT1 -6401

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SEC24D -7134
TMED2 -7071
MCFD2 -7065
MIA3 -7049
FUT3 -7001
TMED7 -6933
SEC24A -6839
SEC13 -6812
ST3GAL4 -6801
ANK2 -6778
TMEM115 -6764
TRAPPC10 -6585
LMAN2 -6558
COPB2 -6532
CD55 -6517
PPP6R1 -6511
ARCN1 -6505
TMED9 -6502
MAN1A2 -6460
MGAT1 -6401
MGAT4B -6279
SEC24C -6236
TBC1D20 -6203
TMED10 -6116
ARF1 -6021
SEC16A -5971
COPE -5961
COG3 -5948
NAPA -5921
KDELR2 -5893
MGAT5 -5854
ARF4 -5812
SEC31A -5766
CSNK1D -5722
SEC24B -5475
TFG -5336
GOLGA2 -5310
STX5 -5300
PPP6C -5241
ACTR1A -5162
COPG1 -5135
FUT8 -5134
KDELR1 -5094
MGAT4A -5018
GBF1 -4981
SPTBN1 -4901
YKT6 -4899
CAPZA1 -4855
B4GALT3 -4852
AREG -4847
NSF -4839
ARFGAP3 -4817
ANK1 -4656
TRAPPC2L -4576
TGFA -4511
CTSC -4446
COG2 -4254
COPB1 -4098
TMED3 -4057
TRAPPC3 -4032
COG5 -3964
COPA -3958
DCTN2 -3957
DYNC1LI2 -3897
NAPG -3872
DCTN5 -3634
DYNC1H1 -3614
USO1 -3509
GOLGB1 -3498
RAB1B -3479
LMAN1 -3431
LMAN2L -3429
MGAT2 -3327
RAB1A -3307
CD59 -3245
SAR1B -2973
DYNC1I2 -2780
SEC23A -2717
DYNC1LI1 -2519
B4GALT2 -2487
ARF3 -2430
MAN2A2 -2336
CNIH3 -1958
DCTN4 -1937
ST6GAL1 -1828
SEC22C -1684
DCTN1 -1635
ARFGAP1 -1587
CAPZA2 -1549
CAPZB -1169
MAN2A1 -1040
MAN1A1 -1021
PPP6R3 -623
NAPB -419
DCTN6 -318
B4GALT1 -262
CNIH1 212
TRAPPC5 239
ANK3 303
SEC23IP 390
BET1 457
SCFD1 485
GOSR1 621
F8 735
COPZ1 782
F5 831
SEC22B 859
KDELR3 976
GOSR2 1238
ARFGAP2 1283
PREB 1446
DCTN3 1457
MGAT4C 1714
TRAPPC4 1781
GORASP1 1903
COG4 1972
SPTAN1 2385
DYNLL1 2509
TRAPPC6B 2584
STX17 2586
B4GALT4 2602
FUCA1 2696
B4GALT6 2881
MAN1C1 3072
TRAPPC1 3089
COG6 3264
SEC22A 3312
BET1L 3487
TRAPPC2 3547
SPTBN2 3883
SERPINA1 4014
ANKRD28 4146
MANEA 4202
COG1 4586
ARF5 4743
COG7 4792
TRAPPC9 5033
COL7A1 5362
ACTR10 5570
DYNLL2 6044
COPG2 6142
SEC16B 6744
COG8 6745
B4GALT5 6846
CHST10 6919
TRAPPC6A 7244



DNA strand elongation

DNA strand elongation
230
set DNA strand elongation
setSize 32
pANOVA 3.66e-09
s.dist 0.602
p.adjustANOVA 1.15e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
GINS1 7335
MCM5 6983
PRIM1 6962
RPA2 6961
GINS2 6909
MCM6 6787
GINS3 6759
MCM2 6755
POLA2 6695
MCM4 6635
PRIM2 6599
GINS4 6560
PCNA 6523
RPA3 6375
LIG1 6206
POLD1 5832
RFC3 5349
POLA1 4949
POLD2 4930
MCM3 4773

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GINS1 7335
MCM5 6983
PRIM1 6962
RPA2 6961
GINS2 6909
MCM6 6787
GINS3 6759
MCM2 6755
POLA2 6695
MCM4 6635
PRIM2 6599
GINS4 6560
PCNA 6523
RPA3 6375
LIG1 6206
POLD1 5832
RFC3 5349
POLA1 4949
POLD2 4930
MCM3 4773
RFC4 4683
MCM8 4587
POLD3 4459
RFC5 4385
RFC2 3878
DNA2 3379
MCM7 2514
CDC45 1783
FEN1 367
POLD4 -3285
RFC1 -4980
RPA1 -5008



PIP3 activates AKT signaling

PIP3 activates AKT signaling
768
set PIP3 activates AKT signaling
setSize 223
pANOVA 6.57e-09
s.dist -0.226
p.adjustANOVA 2.01e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
RRAGC -7009
PIK3AP1 -6957
MET -6878
PDGFRB -6820
TRIB3 -6798
RRAGD -6743
PSMF1 -6663
PSME4 -6450
PSMD2 -6435
PIP4K2C -6335
LCK -6250
FGFR1 -6191
ATF2 -6175
BAD -6118
AKT1S1 -5990
PSMD6 -5951
MAPKAP1 -5936
AGO3 -5803
PSMA2 -5801
PPP2R5A -5740

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RRAGC -7009
PIK3AP1 -6957
MET -6878
PDGFRB -6820
TRIB3 -6798
RRAGD -6743
PSMF1 -6663
PSME4 -6450
PSMD2 -6435
PIP4K2C -6335
LCK -6250
FGFR1 -6191
ATF2 -6175
BAD -6118
AKT1S1 -5990
PSMD6 -5951
MAPKAP1 -5936
AGO3 -5803
PSMA2 -5801
PPP2R5A -5740
PSMA1 -5730
MAF1 -5705
MKRN1 -5695
EZH2 -5631
MTA2 -5619
PSMC1 -5564
SLC38A9 -5539
PSMD3 -5535
AGO2 -5530
PIP4K2A -5495
PSME2 -5481
IRS2 -5461
EGFR -5383
STRN -5363
PSMD1 -5351
LAMTOR5 -5293
CASP9 -5247
PPP2CA -5168
WWP2 -5151
PPP2R5B -5131
PTENP1 -5107
GSK3B -5101
INSR -5097
UBA52 -5068
MAPK1 -5066
CSNK2A1 -5040
PHLPP1 -5029
VAPA -4898
PSMB6 -4888
PSMC6 -4878
AREG -4847
TRIM27 -4835
CHD4 -4830
RRAGB -4819
PSMC4 -4808
TNRC6C -4805
TNKS -4790
PIK3CD -4759
PPP2R1A -4744
PTEN -4721
SNAI1 -4674
PSMD9 -4638
CSNK2A2 -4546
MBD3 -4543
PPP2CB -4523
TGFA -4511
HBEGF -4402
PIK3R1 -4376
PSMB7 -4372
CBX8 -4370
PHC1 -4280
UBB -4263
ATN1 -4249
TNRC6B -4212
PSMA4 -4211
BMI1 -4180
GAB2 -4127
GATAD2A -4108
PSMC5 -4091
CBX4 -4063
HDAC5 -4034
FGF17 -4015
PHLPP2 -3934
RPS6KB2 -3901
PSME3 -3813
KLB -3807
FRS2 -3790
RHEB -3762
GSK3A -3684
MTOR -3683
CDKN1A -3580
RCOR1 -3493
CHUK -3364
RBBP4 -3297
PIP5K1C -3229
TNKS2 -3213
PPARG -3168
SEM1 -3130
PSMA3 -3078
GRB2 -3047
AKT1 -2958
JUN -2934
XIAP -2929
PSMD8 -2928
PIK3CA -2813
FGFR4 -2795
RPS27A -2773
RHOG -2756
PSMA5 -2715
HDAC1 -2676
PDGFA -2660
LAMTOR3 -2631
PIK3CB -2588
PSMD13 -2577
TSC2 -2462
PSMC2 -2389
PSME1 -2348
OTUD3 -2342
PIK3R3 -2279
IRAK1 -2218
PPP2R5D -2117
PRR5 -2094
FOXO4 -2077
RICTOR -2076
TP53 -2020
AKT2 -1946
PSMB3 -1915
PIP5K1A -1831
PSMC3 -1509
EGR1 -1475
PIK3R2 -1355
CHD3 -1321
FGFR3 -1195
PSMB4 -1144
GATAD2B -1092
MDM2 -956
PSMA7 -892
PTPN11 -867
CDKN1B -786
LAMTOR1 -774
PSMB5 -742
REST -593
CD19 -472
PSMD11 -432
HDAC2 -338
LAMTOR2 -148
PSMA6 -126
HDAC3 38
RAC1 44
KITLG 92
HDAC7 130
USP7 134
NEDD4 196
PPP2R5E 283
FGF5 342
SUZ12 346
IL1RL1 347
PDPK1 399
RPTOR 407
PSMB10 423
CREB1 474
FRK 602
UBC 779
RNF146 825
PHC3 843
PIP5K1B 1047
PML 1051
PSMB1 1054
GAB1 1575
IRAK4 1591
TRAF6 1597
MTA1 1810
TNRC6A 1824
LAMTOR4 1834
MLST8 1875
PSMB2 1876
FYN 1937
FGF23 2097
FOXO3 2282
EED 2369
RNF2 2454
RRAGA 2609
PIP4K2B 2639
PPP2R5C 2743
CBX6 2911
ESR2 3316
STUB1 3373
EREG 3467
IRS1 3502
NR4A1 3691
PHC2 3713
SRC 3962
RING1 4067
KDM1A 4224
ERBB3 4249
PSMD12 4303
AGO1 4307
CSNK2B 4415
PSMD4 4567
PPP2R1B 4614
PSMD10 4933
PSMD7 4942
PSMD5 5116
RBBP7 5134
IL1RAP 5361
FOXO1 5418
PSMB9 5491
ERBB2 5534
CNOT6L 5623
MYD88 5939
PSMD14 5974
FLT3LG 6000
USP13 6054
THEM4 6080
MOV10 6408
MTA3 6411
AGO4 6581
MAPK3 6640
SCMH1 6656
FGFR2 6811
PDGFB 6920
SALL4 6934
CBX2 6958



N-glycan trimming in the ER and Calnexin/Calreticulin cycle

N-glycan trimming in the ER and Calnexin/Calreticulin cycle
673
set N-glycan trimming in the ER and Calnexin/Calreticulin cycle
setSize 34
pANOVA 7.03e-09
s.dist -0.574
p.adjustANOVA 2.11e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
CALR -7142
SEL1L -7124
SYVN1 -7108
EDEM1 -7103
CANX -7092
PDIA3 -7086
DERL2 -7046
OS9 -6986
UGGT1 -6954
MLEC -6902
VCP -6720
RNF5 -6629
DERL1 -6423
RNF185 -6359
RNF103 -6135
PRKCSH -5934
PSMC1 -5564
EDEM2 -5520
UBXN1 -5450
UBA52 -5068

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CALR -7142
SEL1L -7124
SYVN1 -7108
EDEM1 -7103
CANX -7092
PDIA3 -7086
DERL2 -7046
OS9 -6986
UGGT1 -6954
MLEC -6902
VCP -6720
RNF5 -6629
DERL1 -6423
RNF185 -6359
RNF103 -6135
PRKCSH -5934
PSMC1 -5564
EDEM2 -5520
UBXN1 -5450
UBA52 -5068
UBB -4263
MAN1B1 -3561
RNF139 -3064
NGLY1 -2909
RPS27A -2773
AMFR -2698
MOGS -2275
EDEM3 -1903
UBC 779
UGGT2 1425
TRIM13 1883
GANAB 2813
RAD23B 3141
ENGASE 6457



Innate Immune System

Innate Immune System
520
set Innate Immune System
setSize 740
pANOVA 9.58e-09
s.dist -0.125
p.adjustANOVA 2.81e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
DNAJC3 -7131
HSP90B1 -7129
PLPP5 -7074
ATP6V0B -7064
MAP3K8 -7060
MAGT1 -7045
CNN2 -7036
ERP44 -7023
LAMP1 -6982
ATP6V0A1 -6979
CEACAM1 -6974
LAMP2 -6966
CTSL -6951
ARSB -6939
GGH -6936
CCR6 -6932
LGALS3 -6923
ATP6V1D -6922
SHC1 -6910
ATP6V0D1 -6908

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DNAJC3 -7131
HSP90B1 -7129
PLPP5 -7074
ATP6V0B -7064
MAP3K8 -7060
MAGT1 -7045
CNN2 -7036
ERP44 -7023
LAMP1 -6982
ATP6V0A1 -6979
CEACAM1 -6974
LAMP2 -6966
CTSL -6951
ARSB -6939
GGH -6936
CCR6 -6932
LGALS3 -6923
ATP6V1D -6922
SHC1 -6910
ATP6V0D1 -6908
MLEC -6902
ATP6V0A2 -6880
S100A11 -6865
P2RX1 -6853
BRI3 -6843
ACTG1 -6841
GNS -6813
PNP -6810
NDUFC2 -6804
C4BPB -6787
CYSTM1 -6768
NEU1 -6752
NFATC3 -6750
VCP -6720
IRAK2 -6713
FTL -6697
PYGB -6693
PSMF1 -6663
ASAH1 -6648
ATP6V0E1 -6622
SURF4 -6593
TOLLIP -6576
NF2 -6559
WASL -6543
DUSP3 -6541
IGF2R -6540
FUCA2 -6538
DNM2 -6535
DNAJC5 -6522
CD55 -6517
TMBIM1 -6493
APP -6492
NFKBIB -6474
EP300 -6470
ALDOA -6463
MAPKAPK2 -6461
HEXB -6455
CLEC10A -6451
PSME4 -6450
DDX3X -6449
ICAM3 -6441
NFKBIA -6437
PSMD2 -6435
DDOST -6429
CDK13 -6415
KCMF1 -6393
KPNB1 -6379
BCL2L1 -6349
UBR4 -6345
ATAD3B -6334
GALNS -6314
CTSA -6288
TAX1BP1 -6281
ATP6V1E1 -6271
PRDX4 -6268
LCK -6250
MAP3K1 -6230
NPC2 -6207
ATF2 -6175
PGAM1 -6174
RAP2B -6173
TMC6 -6114
CD63 -6107
PTPRJ -6103
PDXK -6100
ARPC4 -6094
ITCH -6089
ITPR3 -6088
ATP6V0C -6086
CYLD -6066
MASP1 -6062
DEGS1 -6054
MALT1 -6026
COLEC11 -5996
DUSP4 -5977
PSMD6 -5951
IKBKG -5946
OTUD5 -5944
SRP14 -5938
MVP -5935
PRKCSH -5934
ATP6V1C2 -5929
CCT2 -5926
BPIFB6 -5923
ARL8A -5922
MYO9B -5920
DDX41 -5919
DOK3 -5877
CAPN1 -5850
ECSIT -5840
ANO6 -5826
RAB7A -5810
DIAPH1 -5806
PSMA2 -5801
RIPK2 -5779
MAPKAPK3 -5773
CFL1 -5737
ELK1 -5733
PSMA1 -5730
WASF1 -5712
SNAP23 -5681
IQGAP1 -5663
CRK -5650
GLA -5640
PRKCD -5638
PANX1 -5636
POLR3E -5626
CCT8 -5605
ATP6V1B2 -5574
PSMC1 -5564
RAF1 -5557
CASP10 -5555
HRAS -5543
MAPK12 -5538
PSMD3 -5535
CDC34 -5516
PRKCE -5510
TRIM25 -5492
ISG15 -5488
PSME2 -5481
CD58 -5480
LRRFIP1 -5477
POLR2L -5471
IDH1 -5470
NCF2 -5438
BRK1 -5431
FTH1 -5419
TXNDC5 -5385
ATP6V1G1 -5352
PSMD1 -5351
IQGAP2 -5323
ACTR3 -5296
RHOA -5294
MYO10 -5290
POLR2F -5283
ILF2 -5258
CASP9 -5247
PELI1 -5222
PIK3C3 -5220
PSAP -5218
CTSB -5204
MIF -5176
FOS -5174
TBK1 -5169
PPP2CA -5168
PKM -5137
AAMP -5076
UBA52 -5068
MAPK1 -5066
ACTB -5057
EEF2 -5049
POLR1C -4986
VAMP8 -4969
BPIFB2 -4967
PAK2 -4957
CAB39 -4956
ATP6V1C1 -4946
PSEN1 -4938
ATF1 -4925
GPI -4904
NOS3 -4903
VAPA -4898
PSMB6 -4888
PSMC6 -4878
RAB31 -4876
CAPZA1 -4855
OSTF1 -4843
CTSK -4821
PSMC4 -4808
DSP -4746
PPP2R1A -4744
HMOX2 -4742
MYH9 -4726
GLIPR1 -4691
POLR2E -4667
UBE2V1 -4655
HSPA8 -4654
VAV3 -4642
FAF2 -4640
PSMD9 -4638
TSPAN14 -4626
TANK -4621
PGM1 -4600
NKIRAS2 -4598
OSCAR -4571
PPP2CB -4523
POLR1D -4516
MAP2K4 -4505
VAT1 -4497
ABI1 -4478
BCL10 -4471
CTSC -4446
PPIA -4443
ARPC1B -4429
HSP90AB1 -4426
ATP6V1H -4423
MAP2K7 -4399
MAPK7 -4382
PIK3R1 -4376
PSMB7 -4372
PTK2 -4346
UBE2M -4337
ITPR1 -4321
ITGAV -4312
UBB -4263
TRIM4 -4229
PLEKHO2 -4227
PSMA4 -4211
TOM1 -4199
ARG1 -4179
PPP3R1 -4176
YPEL5 -4173
XRCC5 -4164
EEF1A1 -4138
CUL1 -4129
GAB2 -4127
MAP2K1 -4120
DHX9 -4112
COPB1 -4098
LCN2 -4096
PSMC5 -4091
CAP1 -4085
PPP3CB -4060
UBE2D3 -3997
CNPY3 -3981
NME2 -3974
ORM1 -3973
SARM1 -3956
CKAP4 -3939
TIMP2 -3938
TTR -3924
CREBBP -3888
TAB2 -3878
DUSP7 -3870
RPS6KA1 -3857
PSME3 -3813
FBXW11 -3784
ATP6V1A -3777
HUWE1 -3769
PLCG2 -3766
CPNE1 -3710
LAT -3697
NLRC4 -3690
PDAP1 -3657
DYNC1H1 -3614
TXN -3611
ROCK1 -3594
POLR2H -3593
TMEM179B -3567
SIRPA -3538
COMMD9 -3531
NFKB1 -3507
MYO5A -3500
AP2A2 -3499
GOLGA7 -3421
DUSP6 -3376
WASF2 -3366
CHUK -3364
STBD1 -3361
HSPA6 -3353
MAP2K3 -3342
ATG12 -3333
MEF2A -3308
CD59 -3245
HEBP2 -3167
PA2G4 -3141
SEM1 -3130
RAB5C -3129
PSMA3 -3078
GRB2 -3047
LYN -3038
RPS6KA3 -3030
LAIR1 -3025
WIPF2 -2965
APOB -2964
PLAU -2962
TMEM30A -2956
JUN -2934
IKBKB -2931
PSMD8 -2928
RIPK1 -2886
STK11IP -2838
PIK3CA -2813
GRN -2805
TOMM70 -2797
NCKAP1 -2788
ELMO1 -2779
RPS27A -2773
EEA1 -2764
RHOG -2756
PSMA5 -2715
ADAM10 -2671
S100P -2653
RELA -2632
LAMTOR3 -2631
RHOF -2600
PIK3CB -2588
PSMD13 -2577
MAP3K14 -2575
B2M -2523
DYNC1LI1 -2519
POLR3H -2496
SERPINB6 -2474
ATP11B -2420
QPCT -2416
CANT1 -2398
PSMC2 -2389
TLR9 -2371
MAP2K6 -2351
PSME1 -2348
PRKDC -2300
PRCP -2276
POLR3B -2273
PTPN4 -2238
IRAK1 -2218
C8G -2213
ARPC2 -2209
CDC42 -2172
ARHGAP9 -2170
PPP2R5D -2117
CRISPLD2 -2075
KLRK1 -2060
AGER -2057
POLR3A -2056
KRAS -2044
GDI2 -2026
IST1 -2001
TICAM1 -1956
PSMB3 -1915
MAPK13 -1875
UNC13D -1871
PELI2 -1870
SDCBP -1822
IMPDH1 -1807
POLR3C -1730
CAND1 -1658
CAPZA2 -1549
STAT6 -1541
SLC2A3 -1535
MUC13 -1524
STOM -1523
ARPC5 -1511
PSMC3 -1509
PRKACB -1429
PIK3R2 -1355
YES1 -1340
LY96 -1339
TNIP2 -1314
NFKB2 -1311
VRK3 -1278
UBA3 -1275
QSOX1 -1250
ATP6AP2 -1245
ORM2 -1240
MYO1C -1212
ABI2 -1197
ADAM8 -1193
GYG1 -1167
RPS6KA2 -1149
PSMB4 -1144
ITK -1112
RAP2C -1109
HSP90AA1 -1030
MUC20 -1019
NCKAP1L -972
SOS1 -950
DDX58 -927
UBE2D2 -913
PSMA7 -892
COTL1 -877
ATP6V1F -868
PTPN11 -867
AMPD3 -829
GHDC -827
IKBKE -787
LAMTOR1 -774
PSMB5 -742
SNAP29 -703
RNASET2 -701
MAPK8 -700
DNAJC13 -677
CALM1 -655
BAIAP2 -637
MAN2B1 -600
TRAF2 -577
DHX36 -566
NCSTN -554
SKP1 -544
ATP6V1E2 -534
UNC93B1 -517
BIRC2 -499
CD19 -472
PAFAH1B2 -471
RELB -469
PSMD11 -432
RAB18 -372
TRAF3 -356
ADGRE5 -313
B4GALT1 -262
CMTM6 -259
PGRMC1 -242
GMFG -220
CASP4 -184
LAMTOR2 -148
PSMA6 -126
CPN2 -110
CRACR2A -75
PRDX6 -54
CREG1 -47
AHSG 25
XRCC6 28
RAC1 44
DGAT1 111
RNF135 126
NLRP1 136
NKIRAS1 150
TCIRG1 180
MAPK11 251
PGM2 263
RAP1A 309
STK10 333
FCER1G 380
PPP3CA 381
UBE2K 383
PDPK1 399
PSMB10 423
CREB1 474
CCL22 584
CYB5R3 600
FRK 602
F2 635
LAT2 670
KCNAB2 675
POLR3F 688
ATP6V1G2 690
NOS1 709
BST1 713
ATP6V0D2 747
CSTB 776
UBC 779
SLC27A2 829
IRF3 862
ELMO2 942
PCBP2 974
CRCP 979
NAPRT 988
LGMN 1001
PAK1 1031
PSMB1 1054
PECAM1 1098
SIRPB1 1105
TLR6 1131
PIK3R4 1132
PLD3 1239
GUSB 1260
APAF1 1277
RAB6A 1296
PPIE 1333
MOSPD2 1344
BTRC 1386
ADGRG3 1417
ACTR2 1435
CXCR2 1464
ATP11A 1486
GSN 1496
CTSS 1499
SIGIRR 1500
NCK1 1525
POLR3G 1545
GLB1 1557
LIMK1 1565
IRAK4 1591
TRAF6 1597
RAB3D 1600
RAB10 1625
SUGT1 1662
HTN1 1687
MAVS 1695
PRKACA 1736
MAPK9 1760
SCAMP1 1817
HSPA1A 1835
UBE2N 1836
HERC5 1855
PSMB2 1876
CLEC7A 1881
FADD 1889
ITGAX 1919
BCL2 1925
FYN 1937
CYFIP1 1939
PTPRN2 1971
ABL1 2023
ATP7A 2111
KLRD1 2155
CTSV 2161
AGL 2176
SVIP 2180
SERPINB1 2181
CYBA 2202
ITPR2 2257
MAPK14 2269
NRAS 2310
MGST1 2313
JUP 2314
CARD9 2322
SPTAN1 2385
ARMC8 2401
SLC15A4 2407
MEFV 2468
HTN3 2502
DYNLL1 2509
PLCG1 2511
PLAC8 2524
TAB3 2566
WASF3 2619
CPPED1 2657
FUCA1 2696
HLA-B 2764
CTSD 2812
VAV2 2817
BST2 2868
ARSA 2878
RAB5B 2913
AP1M1 2926
ATG5 2931
MAPK10 2952
RAB27A 3011
ARPC1A 3022
DTX4 3048
PIN1 3074
RPS6KA5 3086
TRAPPC1 3089
POLR3K 3152
CASP8 3157
RAB4B 3174
SLC2A5 3250
CTNNB1 3272
CPNE3 3303
TMEM63A 3357
DBNL 3382
PDZD11 3385
APRT 3389
BIRC3 3477
C5AR2 3489
UBE2D1 3523
SLC11A1 3527
DOCK1 3540
MANBA 3572
RAP1B 3577
TIFA 3587
PTGES2 3607
RAB14 3647
ATOX1 3659
CST3 3732
MAP3K7 3767
ARPC3 3797
LYZ 3804
DYNLT1 3809
HVCN1 3884
ACAA1 3886
SRC 3962
SERPINA1 4014
FABP5 4021
RAB24 4024
CPN1 4039
PLD2 4048
NBEAL2 4086
MRE11 4100
TRIM21 4105
HLA-H 4193
CASP2 4204
RNF216 4252
C2 4264
PSMD12 4303
RAB3A 4309
CPB2 4337
TNFAIP3 4359
METTL7A 4368
SIKE1 4383
VCL 4407
CSNK2B 4415
TIRAP 4446
POLR3D 4454
PLAUR 4485
PTAFR 4486
ATP6V1B1 4549
ACLY 4562
PSMD4 4567
HMOX1 4592
DPP7 4601
PPP2R1B 4614
ANPEP 4690
GAA 4697
APEH 4698
NFATC2 4720
C7 4745
AGPAT2 4769
MUC15 4828
AHCYL1 4874
EPPIN 4893
PYGL 4903
IMPDH2 4910
PSMD10 4933
PSMD7 4942
NLRC5 4976
COMMD3 4983
CAT 5018
PELI3 5019
CD46 5036
ORMDL3 5040
ALPK1 5041
SOCS1 5053
PSMD5 5116
TUBB 5125
LPCAT1 5166
RBSN 5208
C4BPA 5221
CD36 5264
GM2A 5280
DERA 5319
TBC1D10C 5382
GSDMD 5413
PFKL 5437
NOD1 5449
ATG7 5453
NCKIPSD 5477
PSMB9 5491
HMGB1 5546
VNN1 5548
CFD 5558
ACTR10 5570
NIT2 5596
CLU 5647
CTSH 5655
SLCO4C1 5675
ATP6V0E2 5683
LBP 5684
MASP2 5751
ACTR1B 5765
HLA-A 5777
CEP290 5787
HGSNAT 5921
HLA-C 5936
MYD88 5939
PSTPIP1 5948
POLR2K 5962
ALDOC 5970
PSMD14 5974
TRIM32 5977
ATP8A1 5995
PROS1 6053
DHX58 6062
CD4 6074
PLA2G6 6084
CD47 6101
CASP1 6109
C6orf120 6141
AGA 6147
ANXA2 6155
TRIM56 6183
UBA7 6211
CYFIP2 6224
LTA4H 6248
DNASE1L1 6262
NLRX1 6266
ALAD 6318
ITGAL 6325
CD68 6463
ITGB2 6494
DNM1 6505
BPIFB1 6516
PTPN6 6557
C6 6620
MAPK3 6640
IFIH1 6646
TAB1 6687
FGG 6697
SYNGR1 6711
C5AR1 6719
LRG1 6726
HP 6732
CDA 6735
TUBB4B 6758
S100A1 6858
ALDH3B1 6860
ICAM2 6868
SLC44A2 6879
CFI 6891
PYCARD 6900
VTN 6910
MBL2 6911
DSN1 6916
RAB37 6989
CD14 6998
A1BG 7060
NHLRC3 7191
C1R 7201
C5 7218
FGB 7226
C8A 7235
PLA2G2A 7254
GCA 7258
TKFC 7267
UBE2L6 7272
C4B 7286
PLD1 7290
POLR3GL 7315
RNF125 7321
SERPINA3 7328
LEAP2 7329
FGA 7336
C8B 7343
C4A 7346
CFB 7350
C3 7357
C1S 7360
MUC5B 7378
TXNIP 7384
SERPING1 7387



Ribosomal scanning and start codon recognition

Ribosomal scanning and start codon recognition
1014
set Ribosomal scanning and start codon recognition
setSize 58
pANOVA 1.02e-08
s.dist -0.435
p.adjustANOVA 2.93e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
EIF4A1 -6995
EIF3A -6965
EIF5 -6065
EIF4G1 -5901
EIF4B -5898
EIF3I -5279
EIF2S1 -5190
RPS7 -5138
EIF3B -5127
EIF4H -5055
RPS15 -5010
FAU -4990
RPS5 -4778
EIF3G -4724
RPS11 -4702
RPS19 -4661
RPS28 -4652
EIF3J -4539
EIF2S2 -4458
RPS12 -4367

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
EIF4A1 -6995
EIF3A -6965
EIF5 -6065
EIF4G1 -5901
EIF4B -5898
EIF3I -5279
EIF2S1 -5190
RPS7 -5138
EIF3B -5127
EIF4H -5055
RPS15 -5010
FAU -4990
RPS5 -4778
EIF3G -4724
RPS11 -4702
RPS19 -4661
RPS28 -4652
EIF3J -4539
EIF2S2 -4458
RPS12 -4367
EIF3M -4358
RPS9 -4028
RPS29 -3844
EIF3D -3740
EIF2S3 -3669
RPSA -3520
RPS4X -3464
RPS2 -3462
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
RPS15A -3019
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPS27A -2773
RPS6 -2681
RPS18 -2648
RPS13 -2581
RPS23 -2467
EIF3L -2407
EIF3K -2206
RPS4Y1 -2120
RPS20 -1754
RPS8 -1071
RPS25 -937
EIF3F -893
EIF3C -374
EIF1AX -274
RPS3A -179
RPS27 -152
RPS26 419
EIF3H 899
EIF4E 2473
EIF3E 3244
EIF4A2 5593



ER to Golgi Anterograde Transport

ER to Golgi Anterograde Transport
316
set ER to Golgi Anterograde Transport
setSize 122
pANOVA 1.24e-08
s.dist -0.299
p.adjustANOVA 3.49e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
SEC24D -7134
TMED2 -7071
MCFD2 -7065
MIA3 -7049
TMED7 -6933
SEC24A -6839
SEC13 -6812
ANK2 -6778
TMEM115 -6764
TRAPPC10 -6585
LMAN2 -6558
COPB2 -6532
CD55 -6517
PPP6R1 -6511
ARCN1 -6505
TMED9 -6502
SEC24C -6236
TBC1D20 -6203
TMED10 -6116
ARF1 -6021

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SEC24D -7134
TMED2 -7071
MCFD2 -7065
MIA3 -7049
TMED7 -6933
SEC24A -6839
SEC13 -6812
ANK2 -6778
TMEM115 -6764
TRAPPC10 -6585
LMAN2 -6558
COPB2 -6532
CD55 -6517
PPP6R1 -6511
ARCN1 -6505
TMED9 -6502
SEC24C -6236
TBC1D20 -6203
TMED10 -6116
ARF1 -6021
SEC16A -5971
COPE -5961
COG3 -5948
NAPA -5921
KDELR2 -5893
ARF4 -5812
SEC31A -5766
CSNK1D -5722
SEC24B -5475
TFG -5336
GOLGA2 -5310
STX5 -5300
PPP6C -5241
ACTR1A -5162
COPG1 -5135
KDELR1 -5094
GBF1 -4981
SPTBN1 -4901
YKT6 -4899
CAPZA1 -4855
AREG -4847
NSF -4839
ARFGAP3 -4817
ANK1 -4656
TRAPPC2L -4576
TGFA -4511
CTSC -4446
COG2 -4254
COPB1 -4098
TMED3 -4057
TRAPPC3 -4032
COG5 -3964
COPA -3958
DCTN2 -3957
DYNC1LI2 -3897
NAPG -3872
DCTN5 -3634
DYNC1H1 -3614
USO1 -3509
GOLGB1 -3498
RAB1B -3479
LMAN1 -3431
LMAN2L -3429
RAB1A -3307
CD59 -3245
SAR1B -2973
DYNC1I2 -2780
SEC23A -2717
DYNC1LI1 -2519
ARF3 -2430
CNIH3 -1958
DCTN4 -1937
SEC22C -1684
DCTN1 -1635
ARFGAP1 -1587
CAPZA2 -1549
CAPZB -1169
PPP6R3 -623
NAPB -419
DCTN6 -318
CNIH1 212
TRAPPC5 239
ANK3 303
SEC23IP 390
BET1 457
SCFD1 485
GOSR1 621
F8 735
COPZ1 782
F5 831
SEC22B 859
KDELR3 976
GOSR2 1238
ARFGAP2 1283
PREB 1446
DCTN3 1457
TRAPPC4 1781
GORASP1 1903
COG4 1972
SPTAN1 2385
DYNLL1 2509
TRAPPC6B 2584
STX17 2586
TRAPPC1 3089
COG6 3264
SEC22A 3312
BET1L 3487
TRAPPC2 3547
SPTBN2 3883
SERPINA1 4014
ANKRD28 4146
COG1 4586
ARF5 4743
COG7 4792
TRAPPC9 5033
COL7A1 5362
ACTR10 5570
DYNLL2 6044
COPG2 6142
SEC16B 6744
COG8 6745
TRAPPC6A 7244



Selenoamino acid metabolism

Selenoamino acid metabolism
1056
set Selenoamino acid metabolism
setSize 104
pANOVA 1.3e-08
s.dist -0.323
p.adjustANOVA 3.57e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL36AL -6981
SCLY -6834
TXNRD1 -6806
SEPHS2 -6447
RPL19 -5254
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
RPS11 -4702
RPS19 -4661
RPS28 -4652
CBS -4541
RPLP1 -4391
RPS12 -4367
RPL27A -4297

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL36AL -6981
SCLY -6834
TXNRD1 -6806
SEPHS2 -6447
RPL19 -5254
RPS7 -5138
UBA52 -5068
RPL11 -5032
RPL10 -5026
RPS15 -5010
FAU -4990
RPL14 -4978
RPS5 -4778
RPS11 -4702
RPS19 -4661
RPS28 -4652
CBS -4541
RPLP1 -4391
RPS12 -4367
RPL27A -4297
RPLP0 -4290
RPL35A -4159
RPL30 -4081
RPS9 -4028
EEF1E1 -4013
RPL18 -3961
RPL26L1 -3873
RPS29 -3844
RPL6 -3843
RPL28 -3546
GSR -3534
RPSA -3520
RPL8 -3467
RPS4X -3464
RPS2 -3462
RPL29 -3450
RPL32 -3448
RPL36 -3432
RPL37 -3413
RPS17 -3369
RPS24 -3352
RPS14 -3261
RPS27L -3180
RPS10 -3155
RPS15A -3019
RPL7 -2984
RPL34 -2974
RPS21 -2927
RPS16 -2898
RPS3 -2880
RPL13A -2872
RPLP2 -2863
RPL35 -2849
RPS27A -2773
RPL23A -2692
RPL10A -2689
RPS6 -2681
RPS18 -2648
RPL41 -2635
RPS13 -2581
RPL4 -2563
RPS23 -2467
RPL37A -2451
RPL39 -2270
RPL18A -2240
RPL7A -2233
RPS4Y1 -2120
RPL27 -2070
AHCY -1945
RPL23 -1913
RPL24 -1804
RPL38 -1791
RPS20 -1754
RPL26 -1747
PSTK -1545
RPL15 -1313
RPL3 -1165
RPL17 -1119
RPS8 -1071
RPL12 -983
RPS25 -937
RPL13 -706
RPL5 -495
SECISBP2 -410
RPL22L1 -214
RPS3A -179
RPS27 -152
RPL9 261
GNMT 302
RPL31 330
RPS26 419
AIMP2 1067
RPL21 1385
PAPSS2 1548
AIMP1 1790
RPL22 2142
INMT 2159
RPL36A 2875
EEFSEC 3653
PAPSS1 3746
HNMT 4118
MAT1A 6114
SEPSECS 6852
CTH 7240



Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.1.2 (2021-11-01)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 20.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.9.0
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.9.0
## 
## locale:
##  [1] LC_CTYPE=en_AU.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_AU.UTF-8        LC_COLLATE=en_AU.UTF-8    
##  [5] LC_MONETARY=en_AU.UTF-8    LC_MESSAGES=en_AU.UTF-8   
##  [7] LC_PAPER=en_AU.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_AU.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.2.4               GGally_2.1.2               
##  [3] ggplot2_3.3.5               reshape2_1.4.4             
##  [5] beeswarm_0.4.0              gplots_3.1.1               
##  [7] gtools_3.9.2                tibble_3.1.6               
##  [9] dplyr_1.0.7                 echarts4r_0.4.3            
## [11] eulerr_6.1.1                kableExtra_1.3.4           
## [13] mitch_1.4.1                 clusterProfiler_4.0.5      
## [15] DESeq2_1.32.0               SummarizedExperiment_1.22.0
## [17] Biobase_2.52.0              MatrixGenerics_1.4.3       
## [19] matrixStats_0.61.0          GenomicRanges_1.44.0       
## [21] GenomeInfoDb_1.28.4         IRanges_2.26.0             
## [23] S4Vectors_0.30.2            BiocGenerics_0.38.0        
## [25] getDEE2_1.2.0              
## 
## loaded via a namespace (and not attached):
##   [1] shadowtext_0.1.1       fastmatch_1.1-3        systemfonts_1.0.3     
##   [4] plyr_1.8.6             igraph_1.2.11          lazyeval_0.2.2        
##   [7] polylabelr_0.2.0       splines_4.1.2          BiocParallel_1.26.2   
##  [10] digest_0.6.29          yulab.utils_0.0.4      htmltools_0.5.2       
##  [13] GOSemSim_2.18.1        viridis_0.6.2          GO.db_3.13.0          
##  [16] fansi_1.0.0            magrittr_2.0.1         memoise_2.0.1         
##  [19] Biostrings_2.60.2      annotate_1.70.0        graphlayouts_0.8.0    
##  [22] svglite_2.0.0          enrichplot_1.12.3      colorspace_2.0-2      
##  [25] rvest_1.0.2            blob_1.2.2             ggrepel_0.9.1         
##  [28] xfun_0.29              tcltk_4.1.2            crayon_1.4.2          
##  [31] RCurl_1.98-1.5         jsonlite_1.7.2         scatterpie_0.1.7      
##  [34] genefilter_1.74.1      survival_3.2-13        ape_5.6-1             
##  [37] glue_1.6.0             polyclip_1.10-0        gtable_0.3.0          
##  [40] zlibbioc_1.38.0        XVector_0.32.0         webshot_0.5.2         
##  [43] htm2txt_2.1.1          DelayedArray_0.18.0    scales_1.1.1          
##  [46] DOSE_3.18.3            DBI_1.1.2              Rcpp_1.0.7            
##  [49] viridisLite_0.4.0      xtable_1.8-4           gridGraphics_0.5-1    
##  [52] tidytree_0.3.7         bit_4.0.4              htmlwidgets_1.5.4     
##  [55] httr_1.4.2             fgsea_1.18.0           RColorBrewer_1.1-2    
##  [58] ellipsis_0.3.2         pkgconfig_2.0.3        reshape_0.8.8         
##  [61] XML_3.99-0.8           farver_2.1.0           sass_0.4.0            
##  [64] locfit_1.5-9.4         utf8_1.2.2             labeling_0.4.2        
##  [67] ggplotify_0.1.0        tidyselect_1.1.1       rlang_0.4.12          
##  [70] later_1.3.0            AnnotationDbi_1.54.1   munsell_0.5.0         
##  [73] tools_4.1.2            cachem_1.0.6           downloader_0.4        
##  [76] generics_0.1.1         RSQLite_2.2.9          evaluate_0.14         
##  [79] stringr_1.4.0          fastmap_1.1.0          yaml_2.2.1            
##  [82] ggtree_3.0.4           knitr_1.37             bit64_4.0.5           
##  [85] tidygraph_1.2.0        caTools_1.18.2         purrr_0.3.4           
##  [88] KEGGREST_1.32.0        ggraph_2.0.5           nlme_3.1-153          
##  [91] mime_0.12              aplot_0.1.2            xml2_1.3.3            
##  [94] DO.db_2.9              rstudioapi_0.13        compiler_4.1.2        
##  [97] png_0.1-7              testthat_3.1.1         treeio_1.16.2         
## [100] tweenr_1.0.2           geneplotter_1.70.0     bslib_0.3.1           
## [103] stringi_1.7.6          highr_0.9              desc_1.4.0            
## [106] lattice_0.20-45        Matrix_1.4-0           vctrs_0.3.8           
## [109] pillar_1.6.4           lifecycle_1.0.1        jquerylib_0.1.4       
## [112] data.table_1.14.2      cowplot_1.1.1          bitops_1.0-7          
## [115] httpuv_1.6.5           patchwork_1.1.1        qvalue_2.24.0         
## [118] R6_2.5.1               promises_1.2.0.1       KernSmooth_2.23-20    
## [121] gridExtra_2.3          MASS_7.3-54            assertthat_0.2.1      
## [124] rprojroot_2.0.2        withr_2.4.3            GenomeInfoDbData_1.2.6
## [127] grid_4.1.2             ggfun_0.0.4            tidyr_1.1.4           
## [130] rmarkdown_2.11         ggforce_0.3.3          shiny_1.7.1

END of report