Mitch Report

date generated: 2021-05-25

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

##              psf        psb         hcy     folate      vitb12
## A1BG  -0.5800559 -1.4251564 -0.73738014  0.0412627  0.06602231
## AAAS  -0.6096697 -0.8287788  0.26769161  0.2317684  0.39229532
## AACS  -0.3700269 -0.6771814 -0.05724519  0.4461738  0.70183016
## AAGAB -1.2600707 -1.4994722  1.40287399 -0.8398882  0.16247801
## AAK1  -0.4541028 -1.0328131 -0.23257636  1.5132512  0.88663234
## AAMP  -1.5615637 -0.8733084  1.76955365 -0.6831837 -0.04090170

Here are some metrics about the input data profile:

Profile metrics

	Profile metrics
num_genes_in_profile	9869
duplicated_genes_present	0
num_profile_genes_in_sets	5319
num_profile_genes_not_in_sets	4550

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt

Gene sets metrics

	Gene sets metrics
num_genesets	2484
num_genesets_excluded	1343
num_genesets_included	1141

Genes by sector

	psf	psb	hcy	folate	vitb12	Count
1	-1	-1	-1	-1	-1	97
2	1	-1	-1	-1	-1	6
3	-1	1	-1	-1	-1	3
4	1	1	-1	-1	-1	5
5	-1	-1	1	-1	-1	403
6	1	-1	1	-1	-1	8
7	-1	1	1	-1	-1	32
8	1	1	1	-1	-1	5
9	-1	-1	-1	1	-1	106
10	1	-1	-1	1	-1	19
11	-1	1	-1	1	-1	3
12	1	1	-1	1	-1	14
13	-1	-1	1	1	-1	478
14	1	-1	1	1	-1	17
15	-1	1	1	1	-1	24
16	1	1	1	1	-1	12
17	-1	-1	1	1	0	1
18	-1	-1	-1	-1	1	238
19	1	-1	-1	-1	1	30
20	-1	1	-1	-1	1	4
21	1	1	-1	-1	1	3
22	-1	-1	1	-1	1	576
23	1	-1	1	-1	1	12
24	-1	1	1	-1	1	16
25	1	1	1	-1	1	1
26	-1	-1	-1	0	1	1
27	-1	-1	-1	1	1	2150
28	1	-1	-1	1	1	363
29	-1	0	-1	1	1	1
30	-1	1	-1	1	1	31
31	1	1	-1	1	1	42
32	-1	-1	0	1	1	1
33	-1	-1	1	1	1	4929
34	0	-1	1	1	1	1
35	1	-1	1	1	1	181
36	-1	1	1	1	1	28
37	1	1	1	1	1	28

Number of significant gene sets (FDR<0.05)= 65

Gene sets by sector

Gene sets by sector

	s.psf	s.psb	s.hcy	s.folate	s.vitb12	Count
1	1	-1	-1	-1	-1	2
2	-1	1	-1	-1	-1	5
3	1	1	-1	-1	-1	11
4	-1	-1	1	-1	-1	1
5	-1	1	1	-1	-1	1
6	-1	-1	1	1	-1	1
7	-1	1	1	1	-1	1
8	-1	-1	-1	1	1	2
9	-1	1	-1	1	1	1
10	-1	-1	1	1	1	16
11	1	-1	1	1	1	22
12	1	1	1	1	1	2

Interactive enrichment scatterplot

All sets with FDR<0.05. Try hovering over the points.

Top N sets irrespective of FDR. Try hovering over the points.

A heatmap of S values for top results

A plot of effect size versus significance

Significance is the -log2(p.adjustMANOVA) and effect size is the s.dist which is the hypotenuse of the s scores.

Results table

Top N= 50 gene sets

set	setSize	pMANOVA	p.adjustMANOVA	s.dist	s.psf	s.psb	s.hcy	s.folate	s.vitb12	p.psf	p.psb	p.hcy	p.folate	p.vitb12
Metabolism of RNA	498	2.60e-12	2.96e-09	0.2100	-0.06840	-0.06840	0.0942	0.1280	0.09720	0.01000	0.00996	0.000388	1.38e-06	2.52e-04
Cell Cycle	482	2.09e-06	9.46e-04	0.1590	-0.06830	-0.06880	0.1120	0.0551	0.00975	0.01130	0.01070	0.000031	4.09e-02	7.18e-01
Cell Cycle, Mitotic	390	3.10e-06	9.46e-04	0.1660	-0.04720	-0.06860	0.1080	0.0865	0.03710	0.11400	0.02150	0.000277	3.71e-03	2.14e-01
Regulation of expression of SLITs and ROBOs	117	3.32e-06	9.46e-04	0.3060	0.03250	-0.12000	0.1360	0.1880	0.15600	0.54500	0.02530	0.011300	4.73e-04	3.60e-03
rRNA processing	149	5.26e-06	1.12e-03	0.2930	0.01120	-0.12700	0.0637	0.1600	0.20000	0.81400	0.00773	0.181000	7.96e-04	2.78e-05
rRNA processing in the nucleus and cytosol	145	6.68e-06	1.12e-03	0.2910	0.02070	-0.12900	0.0709	0.1590	0.19300	0.66800	0.00734	0.142000	9.99e-04	6.51e-05
M Phase	272	7.16e-06	1.12e-03	0.1940	-0.05790	-0.08680	0.1150	0.1070	0.04360	0.10300	0.01450	0.001140	2.64e-03	2.20e-01
Translation	225	8.53e-06	1.12e-03	0.2220	-0.01570	-0.06120	0.0863	0.1490	0.12500	0.68700	0.11600	0.026700	1.33e-04	1.34e-03
Processing of Capped Intron-Containing Pre-mRNA	175	9.56e-06	1.12e-03	0.2190	-0.13500	-0.01500	0.1100	0.1240	0.04670	0.00214	0.73300	0.012800	4.92e-03	2.89e-01
Activation of NMDA receptors and postsynaptic events	43	9.80e-06	1.12e-03	0.4940	0.19100	0.22800	-0.2800	-0.2280	-0.15800	0.03000	0.00966	0.001510	9.70e-03	7.30e-02
Mitotic Metaphase and Anaphase	186	2.40e-05	2.39e-03	0.2270	-0.02600	-0.05040	0.0940	0.1680	0.10700	0.54300	0.23800	0.027900	8.41e-05	1.27e-02
Neuronal System	127	2.55e-05	2.39e-03	0.2690	0.09190	0.10300	-0.1950	-0.1130	-0.04990	0.07470	0.04610	0.000157	2.83e-02	3.33e-01
Major pathway of rRNA processing in the nucleolus and cytosol	140	2.73e-05	2.39e-03	0.2800	0.01700	-0.11700	0.0733	0.1580	0.18500	0.73000	0.01730	0.136000	1.27e-03	1.66e-04
Mitotic Anaphase	185	3.00e-05	2.45e-03	0.2260	-0.02690	-0.04930	0.0943	0.1650	0.10800	0.53000	0.25000	0.027800	1.13e-04	1.16e-02
Transmission across Chemical Synapses	93	4.58e-05	3.49e-03	0.3020	0.07600	0.12500	-0.2300	-0.1160	-0.05460	0.20600	0.03690	0.000130	5.38e-02	3.64e-01
Neurotransmitter receptors and postsynaptic signal transmission	73	8.46e-05	5.52e-03	0.3480	0.08260	0.18000	-0.1820	-0.1810	-0.12400	0.22300	0.00801	0.007150	7.49e-03	6.65e-02
Signaling by ROBO receptors	146	8.55e-05	5.52e-03	0.2570	0.01430	-0.11100	0.0853	0.1590	0.14400	0.76700	0.02090	0.076400	9.79e-04	2.74e-03
Selenocysteine synthesis	65	8.71e-05	5.52e-03	0.3830	0.11100	-0.14200	0.0997	0.2510	0.20300	0.12300	0.04790	0.165000	4.77e-04	4.80e-03
Peptide chain elongation	64	9.32e-05	5.59e-03	0.3720	0.11300	-0.10600	0.1260	0.2440	0.19800	0.11800	0.14500	0.080700	7.50e-04	6.28e-03
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	81	1.17e-04	6.17e-03	0.3040	0.09750	-0.05630	0.1490	0.2020	0.13000	0.13000	0.38200	0.021000	1.70e-03	4.42e-02
Nonsense-Mediated Decay (NMD)	81	1.17e-04	6.17e-03	0.3040	0.09750	-0.05630	0.1490	0.2020	0.13000	0.13000	0.38200	0.021000	1.70e-03	4.42e-02
G2/M Transition	143	1.22e-04	6.17e-03	0.2400	-0.05020	-0.11700	0.1440	0.1130	0.08860	0.30200	0.01590	0.003050	1.97e-02	6.86e-02
Eukaryotic Translation Elongation	67	1.27e-04	6.17e-03	0.3530	0.11700	-0.09030	0.1300	0.2250	0.18700	0.09860	0.20200	0.067000	1.46e-03	8.14e-03
GTP hydrolysis and joining of the 60S ribosomal subunit	83	1.36e-04	6.17e-03	0.3270	0.08630	-0.09730	0.1060	0.2110	0.18500	0.17500	0.12600	0.095500	9.39e-04	3.66e-03
mRNA Splicing	137	1.37e-04	6.17e-03	0.2180	-0.12700	-0.00454	0.1090	0.1330	0.04100	0.01060	0.92700	0.028200	7.35e-03	4.09e-01
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	69	1.41e-04	6.17e-03	0.3410	0.11400	-0.07350	0.1360	0.2300	0.16300	0.10200	0.29200	0.052000	9.92e-04	1.95e-02
Selenoamino acid metabolism	73	1.47e-04	6.21e-03	0.3500	0.11000	-0.13200	0.0934	0.2170	0.19200	0.10500	0.05090	0.169000	1.38e-03	4.60e-03
Mitotic G2-G2/M phases	145	1.57e-04	6.38e-03	0.2360	-0.04770	-0.11000	0.1370	0.1140	0.09740	0.32300	0.02230	0.004460	1.79e-02	4.37e-02
L13a-mediated translational silencing of Ceruloplasmin expression	82	1.66e-04	6.38e-03	0.3220	0.08540	-0.09010	0.1130	0.2140	0.17200	0.18200	0.15900	0.078200	8.39e-04	7.20e-03
Viral mRNA Translation	65	1.69e-04	6.38e-03	0.3430	0.10900	-0.10600	0.1440	0.2160	0.16500	0.12900	0.13900	0.045400	2.70e-03	2.18e-02
Post NMDA receptor activation events	37	1.73e-04	6.38e-03	0.4750	0.15300	0.22100	-0.2510	-0.2340	-0.18800	0.10800	0.02020	0.008210	1.39e-02	4.78e-02
mRNA Splicing - Major Pathway	129	2.15e-04	7.68e-03	0.2230	-0.11900	-0.01290	0.1200	0.1380	0.04090	0.01960	0.80100	0.018800	7.05e-03	4.25e-01
SRP-dependent cotranslational protein targeting to membrane	81	2.34e-04	7.88e-03	0.3140	0.03160	-0.14000	0.1230	0.2100	0.13800	0.62400	0.03010	0.056300	1.13e-03	3.18e-02
Formation of a pool of free 40S subunits	73	2.35e-04	7.88e-03	0.3350	0.07660	-0.11600	0.1200	0.2080	0.18800	0.25900	0.08660	0.078000	2.21e-03	5.66e-03
PKA-mediated phosphorylation of CREB	11	2.88e-04	9.39e-03	0.7930	0.00732	0.44800	-0.4440	-0.4290	-0.21700	0.96600	0.01020	0.010800	1.38e-02	2.13e-01
Cap-dependent Translation Initiation	90	4.12e-04	1.27e-02	0.2780	0.06430	-0.07120	0.1340	0.1740	0.14000	0.29300	0.24400	0.028300	4.40e-03	2.18e-02
Eukaryotic Translation Initiation	90	4.12e-04	1.27e-02	0.2780	0.06430	-0.07120	0.1340	0.1740	0.14000	0.29300	0.24400	0.028300	4.40e-03	2.18e-02
Eukaryotic Translation Termination	66	4.86e-04	1.46e-02	0.3350	0.09670	-0.08480	0.1260	0.2230	0.17300	0.17500	0.23400	0.077500	1.79e-03	1.50e-02
Metabolism of proteins	1217	5.26e-04	1.52e-02	0.0798	-0.01830	-0.01470	0.0382	0.0557	0.03540	0.30100	0.40500	0.030700	1.64e-03	4.53e-02
Regulation of TP53 Activity through Methylation	16	5.32e-04	1.52e-02	0.7490	-0.25500	-0.36800	-0.0393	0.4040	0.44300	0.07710	0.01090	0.786000	5.13e-03	2.18e-03
Cellular responses to stress	425	5.49e-04	1.53e-02	0.1200	0.01190	0.00575	0.0801	0.0782	0.04020	0.67700	0.84100	0.005160	6.31e-03	1.61e-01
PLC beta mediated events	29	5.89e-04	1.60e-02	0.5270	-0.08750	0.05870	-0.1530	-0.3890	-0.30300	0.41500	0.58400	0.155000	2.92e-04	4.75e-03
Response of EIF2AK4 (GCN2) to amino acid deficiency	72	6.12e-04	1.62e-02	0.3100	0.10200	-0.11900	0.1130	0.1910	0.15100	0.13600	0.08200	0.097300	5.25e-03	2.75e-02
Separation of Sister Chromatids	141	7.90e-04	2.05e-02	0.2260	-0.05720	-0.06920	0.0786	0.1610	0.10400	0.24300	0.15800	0.109000	1.01e-03	3.32e-02
Negative regulation of NMDA receptor-mediated neuronal transmission	11	8.24e-04	2.09e-02	0.7860	0.57300	0.19200	-0.4100	-0.1740	-0.23100	0.00100	0.27000	0.018500	3.17e-01	1.85e-01
Ca-dependent events	21	8.71e-04	2.16e-02	0.6030	0.00308	0.28500	-0.1930	-0.3940	-0.29900	0.98100	0.02360	0.125000	1.80e-03	1.76e-02
PKA activation	10	1.03e-03	2.50e-02	0.7750	0.00747	0.42200	-0.4610	-0.3950	-0.23200	0.96700	0.02080	0.011600	3.04e-02	2.04e-01
Heparan sulfate/heparin (HS-GAG) metabolism	19	1.09e-03	2.59e-02	0.5230	0.06370	-0.16900	-0.3490	-0.3020	-0.16600	0.63100	0.20200	0.008390	2.25e-02	2.11e-01
Cellular responses to external stimuli	430	1.20e-03	2.79e-02	0.1130	0.00964	0.00158	0.0781	0.0737	0.03510	0.73500	0.95600	0.006070	9.65e-03	2.18e-01
Defective CFTR causes cystic fibrosis	51	1.26e-03	2.86e-02	0.4000	-0.08480	-0.15900	0.0433	0.2390	0.26200	0.29500	0.04960	0.594000	3.16e-03	1.22e-03

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Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pMANOVA	p.adjustMANOVA	s.dist	s.psf	s.psb	s.hcy	s.folate	s.vitb12	p.psf	p.psb	p.hcy	p.folate	p.vitb12
Metabolism of RNA	498	2.60e-12	2.96e-09	0.2100	-6.84e-02	-0.068400	9.42e-02	1.28e-01	0.097200	0.010000	0.00996	0.000388	1.38e-06	2.52e-04
Cell Cycle	482	2.09e-06	9.46e-04	0.1590	-6.83e-02	-0.068800	1.12e-01	5.51e-02	0.009750	0.011300	0.01070	0.000031	4.09e-02	7.18e-01
Cell Cycle, Mitotic	390	3.10e-06	9.46e-04	0.1660	-4.72e-02	-0.068600	1.08e-01	8.65e-02	0.037100	0.114000	0.02150	0.000277	3.71e-03	2.14e-01
Regulation of expression of SLITs and ROBOs	117	3.32e-06	9.46e-04	0.3060	3.25e-02	-0.120000	1.36e-01	1.88e-01	0.156000	0.545000	0.02530	0.011300	4.73e-04	3.60e-03
rRNA processing	149	5.26e-06	1.12e-03	0.2930	1.12e-02	-0.127000	6.37e-02	1.60e-01	0.200000	0.814000	0.00773	0.181000	7.96e-04	2.78e-05
rRNA processing in the nucleus and cytosol	145	6.68e-06	1.12e-03	0.2910	2.07e-02	-0.129000	7.09e-02	1.59e-01	0.193000	0.668000	0.00734	0.142000	9.99e-04	6.51e-05
M Phase	272	7.16e-06	1.12e-03	0.1940	-5.79e-02	-0.086800	1.15e-01	1.07e-01	0.043600	0.103000	0.01450	0.001140	2.64e-03	2.20e-01
Translation	225	8.53e-06	1.12e-03	0.2220	-1.57e-02	-0.061200	8.63e-02	1.49e-01	0.125000	0.687000	0.11600	0.026700	1.33e-04	1.34e-03
Processing of Capped Intron-Containing Pre-mRNA	175	9.56e-06	1.12e-03	0.2190	-1.35e-01	-0.015000	1.10e-01	1.24e-01	0.046700	0.002140	0.73300	0.012800	4.92e-03	2.89e-01
Activation of NMDA receptors and postsynaptic events	43	9.80e-06	1.12e-03	0.4940	1.91e-01	0.228000	-2.80e-01	-2.28e-01	-0.158000	0.030000	0.00966	0.001510	9.70e-03	7.30e-02
Mitotic Metaphase and Anaphase	186	2.40e-05	2.39e-03	0.2270	-2.60e-02	-0.050400	9.40e-02	1.68e-01	0.107000	0.543000	0.23800	0.027900	8.41e-05	1.27e-02
Neuronal System	127	2.55e-05	2.39e-03	0.2690	9.19e-02	0.103000	-1.95e-01	-1.13e-01	-0.049900	0.074700	0.04610	0.000157	2.83e-02	3.33e-01
Major pathway of rRNA processing in the nucleolus and cytosol	140	2.73e-05	2.39e-03	0.2800	1.70e-02	-0.117000	7.33e-02	1.58e-01	0.185000	0.730000	0.01730	0.136000	1.27e-03	1.66e-04
Mitotic Anaphase	185	3.00e-05	2.45e-03	0.2260	-2.69e-02	-0.049300	9.43e-02	1.65e-01	0.108000	0.530000	0.25000	0.027800	1.13e-04	1.16e-02
Transmission across Chemical Synapses	93	4.58e-05	3.49e-03	0.3020	7.60e-02	0.125000	-2.30e-01	-1.16e-01	-0.054600	0.206000	0.03690	0.000130	5.38e-02	3.64e-01
Neurotransmitter receptors and postsynaptic signal transmission	73	8.46e-05	5.52e-03	0.3480	8.26e-02	0.180000	-1.82e-01	-1.81e-01	-0.124000	0.223000	0.00801	0.007150	7.49e-03	6.65e-02
Signaling by ROBO receptors	146	8.55e-05	5.52e-03	0.2570	1.43e-02	-0.111000	8.53e-02	1.59e-01	0.144000	0.767000	0.02090	0.076400	9.79e-04	2.74e-03
Selenocysteine synthesis	65	8.71e-05	5.52e-03	0.3830	1.11e-01	-0.142000	9.97e-02	2.51e-01	0.203000	0.123000	0.04790	0.165000	4.77e-04	4.80e-03
Peptide chain elongation	64	9.32e-05	5.59e-03	0.3720	1.13e-01	-0.106000	1.26e-01	2.44e-01	0.198000	0.118000	0.14500	0.080700	7.50e-04	6.28e-03
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	81	1.17e-04	6.17e-03	0.3040	9.75e-02	-0.056300	1.49e-01	2.02e-01	0.130000	0.130000	0.38200	0.021000	1.70e-03	4.42e-02
Nonsense-Mediated Decay (NMD)	81	1.17e-04	6.17e-03	0.3040	9.75e-02	-0.056300	1.49e-01	2.02e-01	0.130000	0.130000	0.38200	0.021000	1.70e-03	4.42e-02
G2/M Transition	143	1.22e-04	6.17e-03	0.2400	-5.02e-02	-0.117000	1.44e-01	1.13e-01	0.088600	0.302000	0.01590	0.003050	1.97e-02	6.86e-02
Eukaryotic Translation Elongation	67	1.27e-04	6.17e-03	0.3530	1.17e-01	-0.090300	1.30e-01	2.25e-01	0.187000	0.098600	0.20200	0.067000	1.46e-03	8.14e-03
GTP hydrolysis and joining of the 60S ribosomal subunit	83	1.36e-04	6.17e-03	0.3270	8.63e-02	-0.097300	1.06e-01	2.11e-01	0.185000	0.175000	0.12600	0.095500	9.39e-04	3.66e-03
mRNA Splicing	137	1.37e-04	6.17e-03	0.2180	-1.27e-01	-0.004540	1.09e-01	1.33e-01	0.041000	0.010600	0.92700	0.028200	7.35e-03	4.09e-01
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	69	1.41e-04	6.17e-03	0.3410	1.14e-01	-0.073500	1.36e-01	2.30e-01	0.163000	0.102000	0.29200	0.052000	9.92e-04	1.95e-02
Selenoamino acid metabolism	73	1.47e-04	6.21e-03	0.3500	1.10e-01	-0.132000	9.34e-02	2.17e-01	0.192000	0.105000	0.05090	0.169000	1.38e-03	4.60e-03
Mitotic G2-G2/M phases	145	1.57e-04	6.38e-03	0.2360	-4.77e-02	-0.110000	1.37e-01	1.14e-01	0.097400	0.323000	0.02230	0.004460	1.79e-02	4.37e-02
L13a-mediated translational silencing of Ceruloplasmin expression	82	1.66e-04	6.38e-03	0.3220	8.54e-02	-0.090100	1.13e-01	2.14e-01	0.172000	0.182000	0.15900	0.078200	8.39e-04	7.20e-03
Viral mRNA Translation	65	1.69e-04	6.38e-03	0.3430	1.09e-01	-0.106000	1.44e-01	2.16e-01	0.165000	0.129000	0.13900	0.045400	2.70e-03	2.18e-02
Post NMDA receptor activation events	37	1.73e-04	6.38e-03	0.4750	1.53e-01	0.221000	-2.51e-01	-2.34e-01	-0.188000	0.108000	0.02020	0.008210	1.39e-02	4.78e-02
mRNA Splicing - Major Pathway	129	2.15e-04	7.68e-03	0.2230	-1.19e-01	-0.012900	1.20e-01	1.38e-01	0.040900	0.019600	0.80100	0.018800	7.05e-03	4.25e-01
SRP-dependent cotranslational protein targeting to membrane	81	2.34e-04	7.88e-03	0.3140	3.16e-02	-0.140000	1.23e-01	2.10e-01	0.138000	0.624000	0.03010	0.056300	1.13e-03	3.18e-02
Formation of a pool of free 40S subunits	73	2.35e-04	7.88e-03	0.3350	7.66e-02	-0.116000	1.20e-01	2.08e-01	0.188000	0.259000	0.08660	0.078000	2.21e-03	5.66e-03
PKA-mediated phosphorylation of CREB	11	2.88e-04	9.39e-03	0.7930	7.32e-03	0.448000	-4.44e-01	-4.29e-01	-0.217000	0.966000	0.01020	0.010800	1.38e-02	2.13e-01
Cap-dependent Translation Initiation	90	4.12e-04	1.27e-02	0.2780	6.43e-02	-0.071200	1.34e-01	1.74e-01	0.140000	0.293000	0.24400	0.028300	4.40e-03	2.18e-02
Eukaryotic Translation Initiation	90	4.12e-04	1.27e-02	0.2780	6.43e-02	-0.071200	1.34e-01	1.74e-01	0.140000	0.293000	0.24400	0.028300	4.40e-03	2.18e-02
Eukaryotic Translation Termination	66	4.86e-04	1.46e-02	0.3350	9.67e-02	-0.084800	1.26e-01	2.23e-01	0.173000	0.175000	0.23400	0.077500	1.79e-03	1.50e-02
Metabolism of proteins	1217	5.26e-04	1.52e-02	0.0798	-1.83e-02	-0.014700	3.82e-02	5.57e-02	0.035400	0.301000	0.40500	0.030700	1.64e-03	4.53e-02
Regulation of TP53 Activity through Methylation	16	5.32e-04	1.52e-02	0.7490	-2.55e-01	-0.368000	-3.93e-02	4.04e-01	0.443000	0.077100	0.01090	0.786000	5.13e-03	2.18e-03
Cellular responses to stress	425	5.49e-04	1.53e-02	0.1200	1.19e-02	0.005750	8.01e-02	7.82e-02	0.040200	0.677000	0.84100	0.005160	6.31e-03	1.61e-01
PLC beta mediated events	29	5.89e-04	1.60e-02	0.5270	-8.75e-02	0.058700	-1.53e-01	-3.89e-01	-0.303000	0.415000	0.58400	0.155000	2.92e-04	4.75e-03
Response of EIF2AK4 (GCN2) to amino acid deficiency	72	6.12e-04	1.62e-02	0.3100	1.02e-01	-0.119000	1.13e-01	1.91e-01	0.151000	0.136000	0.08200	0.097300	5.25e-03	2.75e-02
Separation of Sister Chromatids	141	7.90e-04	2.05e-02	0.2260	-5.72e-02	-0.069200	7.86e-02	1.61e-01	0.104000	0.243000	0.15800	0.109000	1.01e-03	3.32e-02
Negative regulation of NMDA receptor-mediated neuronal transmission	11	8.24e-04	2.09e-02	0.7860	5.73e-01	0.192000	-4.10e-01	-1.74e-01	-0.231000	0.001000	0.27000	0.018500	3.17e-01	1.85e-01
Ca-dependent events	21	8.71e-04	2.16e-02	0.6030	3.08e-03	0.285000	-1.93e-01	-3.94e-01	-0.299000	0.981000	0.02360	0.125000	1.80e-03	1.76e-02
PKA activation	10	1.03e-03	2.50e-02	0.7750	7.47e-03	0.422000	-4.61e-01	-3.95e-01	-0.232000	0.967000	0.02080	0.011600	3.04e-02	2.04e-01
Heparan sulfate/heparin (HS-GAG) metabolism	19	1.09e-03	2.59e-02	0.5230	6.37e-02	-0.169000	-3.49e-01	-3.02e-01	-0.166000	0.631000	0.20200	0.008390	2.25e-02	2.11e-01
Cellular responses to external stimuli	430	1.20e-03	2.79e-02	0.1130	9.64e-03	0.001580	7.81e-02	7.37e-02	0.035100	0.735000	0.95600	0.006070	9.65e-03	2.18e-01
Defective CFTR causes cystic fibrosis	51	1.26e-03	2.86e-02	0.4000	-8.48e-02	-0.159000	4.33e-02	2.39e-01	0.262000	0.295000	0.04960	0.594000	3.16e-03	1.22e-03
Signaling by GPCR	195	1.28e-03	2.86e-02	0.1960	1.78e-02	0.069900	-5.44e-02	-1.44e-01	-0.097600	0.670000	0.09400	0.192000	5.88e-04	1.94e-02
RNA Polymerase II Transcription Termination	35	1.59e-03	3.48e-02	0.3940	-2.46e-01	0.069000	2.69e-01	1.28e-01	-0.040200	0.011900	0.48000	0.005940	1.91e-01	6.81e-01
CaM pathway	20	1.71e-03	3.60e-02	0.5940	-1.17e-02	0.281000	-1.73e-01	-4.10e-01	-0.274000	0.928000	0.02950	0.181000	1.49e-03	3.42e-02
Calmodulin induced events	20	1.71e-03	3.60e-02	0.5940	-1.17e-02	0.281000	-1.73e-01	-4.10e-01	-0.274000	0.928000	0.02950	0.181000	1.49e-03	3.42e-02
NOTCH3 Activation and Transmission of Signal to the Nucleus	15	1.79e-03	3.60e-02	0.6780	-8.37e-02	0.046000	-8.89e-02	5.47e-01	0.378000	0.575000	0.75800	0.551000	2.42e-04	1.13e-02
Influenza Viral RNA Transcription and Replication	106	1.80e-03	3.60e-02	0.2390	3.20e-02	-0.051200	1.17e-01	1.57e-01	0.124000	0.570000	0.36400	0.038700	5.26e-03	2.84e-02
Infectious disease	507	1.80e-03	3.60e-02	0.1070	-1.93e-02	-0.039100	9.21e-02	3.21e-02	-0.004780	0.463000	0.13800	0.000465	2.23e-01	8.56e-01
Arachidonic acid metabolism	21	1.88e-03	3.69e-02	0.4880	1.45e-01	-0.169000	-3.98e-01	-1.49e-01	-0.089000	0.250000	0.18000	0.001610	2.38e-01	4.80e-01
GPCR downstream signalling	178	2.07e-03	4.00e-02	0.1960	1.03e-03	0.061500	-6.44e-02	-1.44e-01	-0.100000	0.981000	0.15900	0.141000	1.01e-03	2.17e-02
Nicotinamide salvaging	10	2.14e-03	4.07e-02	0.8180	-6.38e-02	-0.380000	4.09e-01	-2.92e-01	-0.517000	0.727000	0.03760	0.025000	1.10e-01	4.64e-03
Translesion Synthesis by POLH	16	2.23e-03	4.12e-02	0.6750	-1.85e-01	-0.213000	-2.07e-02	4.72e-01	0.391000	0.201000	0.14000	0.886000	1.09e-03	6.74e-03
Immune System	1091	2.24e-03	4.12e-02	0.0908	-3.15e-05	0.020200	6.54e-02	-3.12e-02	-0.050800	0.999000	0.27500	0.000415	9.20e-02	6.11e-03
Anti-inflammatory response favouring Leishmania parasite infection	51	2.64e-03	4.70e-02	0.3680	-6.33e-02	0.126000	-9.95e-02	-2.52e-01	-0.205000	0.435000	0.11900	0.220000	1.85e-03	1.13e-02
Leishmania parasite growth and survival	51	2.64e-03	4.70e-02	0.3680	-6.33e-02	0.126000	-9.95e-02	-2.52e-01	-0.205000	0.435000	0.11900	0.220000	1.85e-03	1.13e-02
DNA Replication Pre-Initiation	66	2.80e-03	4.91e-02	0.3180	-2.62e-02	-0.101000	1.02e-01	2.09e-01	0.190000	0.713000	0.15800	0.151000	3.35e-03	7.67e-03
Autodegradation of the E3 ubiquitin ligase COP1	43	3.08e-03	5.26e-02	0.3930	-9.84e-02	-0.181000	1.30e-01	2.20e-01	0.215000	0.265000	0.04000	0.140000	1.27e-02	1.47e-02
Cell Cycle Checkpoints	212	3.09e-03	5.26e-02	0.1620	-5.40e-02	-0.040800	8.35e-02	1.07e-01	0.057000	0.178000	0.30800	0.037300	7.72e-03	1.55e-01
Cytokine Signaling in Immune system	411	3.76e-03	6.24e-02	0.1640	-4.82e-02	0.014900	1.03e-01	-7.30e-02	-0.092400	0.097500	0.60900	0.000394	1.21e-02	1.49e-03
Hh mutants are degraded by ERAD	46	3.77e-03	6.24e-02	0.3810	-1.02e-01	-0.117000	4.90e-02	2.46e-01	0.241000	0.234000	0.17000	0.566000	3.97e-03	4.75e-03
G alpha (i) signalling events	85	3.88e-03	6.33e-02	0.2570	7.70e-02	0.047000	-8.91e-02	-1.83e-01	-0.127000	0.221000	0.45500	0.156000	3.58e-03	4.32e-02
Miscellaneous transport and binding events	14	4.31e-03	6.93e-02	0.5130	-2.66e-01	0.245000	-2.10e-01	-8.78e-02	-0.284000	0.084800	0.11300	0.174000	5.70e-01	6.55e-02
Stabilization of p53	48	4.48e-03	7.05e-02	0.3630	-1.20e-01	-0.176000	1.12e-01	1.82e-01	0.202000	0.151000	0.03550	0.182000	2.90e-02	1.53e-02
DAG and IP3 signaling	26	4.55e-03	7.05e-02	0.4960	-2.60e-02	0.107000	-9.96e-02	-4.04e-01	-0.247000	0.818000	0.34400	0.380000	3.63e-04	2.95e-02
Regulation of mRNA stability by proteins that bind AU-rich elements	73	4.60e-03	7.05e-02	0.2990	-1.87e-01	-0.146000	1.59e-01	5.82e-02	0.066900	0.005890	0.03120	0.019200	3.91e-01	3.24e-01
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	15	4.64e-03	7.05e-02	0.6340	2.28e-01	0.386000	-3.54e-01	-1.99e-01	-0.190000	0.127000	0.00963	0.017600	1.81e-01	2.03e-01
Signal Transduction	1263	4.81e-03	7.22e-02	0.0904	-1.12e-02	0.041900	3.56e-02	-5.50e-02	-0.044800	0.519000	0.01610	0.040800	1.58e-03	1.01e-02
RUNX1 regulates transcription of genes involved in differentiation of HSCs	55	5.05e-03	7.48e-02	0.3590	3.00e-02	-0.152000	4.38e-02	1.98e-01	0.252000	0.701000	0.05130	0.575000	1.10e-02	1.26e-03
Assembly of collagen fibrils and other multimeric structures	10	5.35e-03	7.82e-02	0.7710	6.61e-01	0.068700	-3.82e-01	-2.86e-02	0.081300	0.000296	0.70700	0.036400	8.76e-01	6.56e-01
DNA Repair	232	6.06e-03	8.48e-02	0.1610	-3.72e-02	-0.073100	-7.99e-03	1.24e-01	0.061700	0.332000	0.05660	0.835000	1.18e-03	1.08e-01
mRNA 3’-end processing	28	6.09e-03	8.48e-02	0.4450	-3.40e-01	0.035100	2.78e-01	3.67e-02	-0.050100	0.001860	0.74800	0.011000	7.37e-01	6.46e-01
Cardiac conduction	40	6.10e-03	8.48e-02	0.3060	1.49e-01	0.108000	7.07e-04	-2.44e-01	-0.015800	0.104000	0.23700	0.994000	7.58e-03	8.63e-01
The role of GTSE1 in G2/M progression after G2 checkpoint	51	6.11e-03	8.48e-02	0.3540	-7.93e-02	-0.176000	8.12e-02	1.90e-01	0.214000	0.328000	0.03040	0.316000	1.91e-02	8.41e-03
Meiosis	39	6.17e-03	8.48e-02	0.4130	-2.47e-01	-0.221000	1.62e-01	-5.80e-03	-0.186000	0.007740	0.01720	0.080600	9.50e-01	4.46e-02
Influenza Infection	123	6.44e-03	8.75e-02	0.2040	2.14e-02	-0.045400	9.86e-02	1.42e-01	0.096700	0.683000	0.38600	0.059800	6.79e-03	6.50e-02
Synaptic adhesion-like molecules	10	7.08e-03	9.20e-02	0.6300	4.52e-01	-0.004580	-3.07e-01	-5.21e-02	-0.309000	0.013300	0.98000	0.092800	7.76e-01	9.06e-02
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	43	7.13e-03	9.20e-02	0.3960	-5.04e-02	-0.186000	4.81e-02	2.52e-01	0.233000	0.568000	0.03530	0.586000	4.29e-03	8.37e-03
p53-Independent DNA Damage Response	43	7.13e-03	9.20e-02	0.3960	-5.04e-02	-0.186000	4.81e-02	2.52e-01	0.233000	0.568000	0.03530	0.586000	4.29e-03	8.37e-03
p53-Independent G1/S DNA damage checkpoint	43	7.13e-03	9.20e-02	0.3960	-5.04e-02	-0.186000	4.81e-02	2.52e-01	0.233000	0.568000	0.03530	0.586000	4.29e-03	8.37e-03
Assembly and cell surface presentation of NMDA receptors	12	7.18e-03	9.20e-02	0.6840	4.85e-01	0.217000	-3.85e-01	-1.27e-01	-0.148000	0.003640	0.19400	0.021100	4.45e-01	3.73e-01
APC/C-mediated degradation of cell cycle proteins	73	7.42e-03	9.23e-02	0.3010	3.81e-02	-0.131000	3.95e-02	2.15e-01	0.157000	0.574000	0.05340	0.560000	1.55e-03	2.10e-02
Regulation of mitotic cell cycle	73	7.42e-03	9.23e-02	0.3010	3.81e-02	-0.131000	3.95e-02	2.15e-01	0.157000	0.574000	0.05340	0.560000	1.55e-03	2.10e-02
G-protein mediated events	32	7.44e-03	9.23e-02	0.4240	-7.93e-02	0.049100	-1.30e-01	-3.16e-01	-0.233000	0.438000	0.63100	0.205000	2.02e-03	2.26e-02
CDT1 association with the CDC6:ORC:origin complex	44	7.59e-03	9.31e-02	0.3840	-4.03e-02	-0.124000	5.48e-02	2.57e-01	0.249000	0.644000	0.15400	0.530000	3.27e-03	4.39e-03
Signaling by NOTCH4	67	7.82e-03	9.49e-02	0.2820	-7.65e-02	-0.113000	1.30e-01	1.68e-01	0.126000	0.280000	0.11100	0.066200	1.75e-02	7.42e-02
Maturation of nucleoprotein	10	8.01e-03	9.62e-02	0.7130	-6.31e-03	-0.136000	5.48e-01	-1.15e-01	-0.420000	0.972000	0.45600	0.002680	5.28e-01	2.15e-02
FCGR3A-mediated IL10 synthesis	22	8.17e-03	9.71e-02	0.4780	-1.15e-01	0.180000	-1.54e-01	-3.59e-01	-0.176000	0.352000	0.14500	0.212000	3.61e-03	1.54e-01
Mitotic Prometaphase	146	8.26e-03	9.71e-02	0.1860	-9.62e-02	-0.056800	1.26e-01	7.74e-02	0.011400	0.045700	0.23800	0.008720	1.08e-01	8.12e-01
G1/S DNA Damage Checkpoints	57	8.36e-03	9.73e-02	0.3240	-6.02e-02	-0.191000	9.10e-02	1.56e-01	0.180000	0.432000	0.01260	0.235000	4.20e-02	1.91e-02
Inositol phosphate metabolism	29	8.64e-03	9.96e-02	0.3760	-7.92e-04	0.120000	-3.56e-02	-3.51e-01	-0.052100	0.994000	0.26600	0.740000	1.09e-03	6.27e-01
GPVI-mediated activation cascade	23	9.44e-03	1.08e-01	0.5210	-6.17e-03	0.388000	2.32e-01	-1.15e-01	-0.232000	0.959000	0.00129	0.053900	3.41e-01	5.47e-02
Neurotransmitter release cycle	18	9.58e-03	1.08e-01	0.5660	2.08e-01	0.034100	-5.11e-01	1.83e-03	0.123000	0.127000	0.80200	0.000175	9.89e-01	3.65e-01
Mitochondrial translation elongation	81	9.72e-03	1.09e-01	0.2830	6.12e-03	-0.098300	2.00e-02	2.19e-01	0.147000	0.924000	0.12700	0.756000	6.64e-04	2.23e-02
p53-Dependent G1 DNA Damage Response	55	1.01e-02	1.10e-01	0.3190	-8.96e-02	-0.192000	1.15e-01	1.30e-01	0.164000	0.251000	0.01400	0.141000	9.64e-02	3.56e-02
p53-Dependent G1/S DNA damage checkpoint	55	1.01e-02	1.10e-01	0.3190	-8.96e-02	-0.192000	1.15e-01	1.30e-01	0.164000	0.251000	0.01400	0.141000	9.64e-02	3.56e-02
Regulation of activated PAK-2p34 by proteasome mediated degradation	41	1.02e-02	1.10e-01	0.3800	-9.46e-02	-0.181000	8.17e-02	2.17e-01	0.221000	0.295000	0.04550	0.366000	1.61e-02	1.44e-02
Orc1 removal from chromatin	55	1.03e-02	1.11e-01	0.3300	1.83e-03	-0.139000	7.52e-02	2.19e-01	0.189000	0.981000	0.07430	0.336000	4.93e-03	1.52e-02
Mitochondrial translation	86	1.04e-02	1.11e-01	0.2660	-1.88e-02	-0.080900	3.15e-02	2.05e-01	0.144000	0.763000	0.19600	0.614000	1.04e-03	2.16e-02
Assembly of the pre-replicative complex	53	1.08e-02	1.15e-01	0.3390	-6.86e-03	-0.085400	5.96e-02	2.29e-01	0.226000	0.931000	0.28300	0.454000	3.90e-03	4.47e-03
Transcriptional regulation by RUNX1	122	1.10e-02	1.15e-01	0.2020	2.53e-02	-0.080800	6.67e-02	9.31e-02	0.143000	0.630000	0.12500	0.205000	7.69e-02	6.54e-03
Deadenylation-dependent mRNA decay	49	1.21e-02	1.25e-01	0.2470	-1.46e-01	0.075300	7.98e-02	1.65e-01	0.020800	0.077500	0.36300	0.334000	4.61e-02	8.01e-01
Integrin signaling	16	1.25e-02	1.25e-01	0.7110	-3.18e-01	0.102000	4.54e-01	-3.66e-01	-0.232000	0.027800	0.47900	0.001690	1.13e-02	1.08e-01
Platelet Aggregation (Plug Formation)	16	1.25e-02	1.25e-01	0.7110	-3.18e-01	0.102000	4.54e-01	-3.66e-01	-0.232000	0.027800	0.47900	0.001690	1.13e-02	1.08e-01
G alpha (s) signalling events	35	1.26e-02	1.25e-01	0.3690	-1.69e-01	-0.097100	-1.30e-01	-2.08e-01	-0.195000	0.083700	0.32000	0.184000	3.32e-02	4.61e-02
ECM proteoglycans	10	1.26e-02	1.25e-01	0.6460	-4.53e-02	-0.311000	-2.51e-01	-4.12e-01	-0.294000	0.804000	0.08900	0.170000	2.42e-02	1.07e-01
G2/M Checkpoints	108	1.27e-02	1.25e-01	0.2090	-7.98e-02	-0.068000	9.74e-02	1.29e-01	0.081900	0.153000	0.22300	0.081200	2.13e-02	1.43e-01
Reproduction	43	1.27e-02	1.25e-01	0.3610	-2.43e-01	-0.170000	1.13e-01	-3.45e-03	-0.172000	0.005910	0.05340	0.199000	9.69e-01	5.09e-02
Activated NOTCH1 Transmits Signal to the Nucleus	19	1.28e-02	1.25e-01	0.4980	-4.39e-02	-0.016100	-1.54e-01	4.36e-01	0.180000	0.741000	0.90300	0.246000	1.01e-03	1.75e-01
Negative regulation of NOTCH4 signaling	47	1.33e-02	1.28e-01	0.3320	-6.67e-02	-0.149000	1.27e-01	1.78e-01	0.189000	0.430000	0.07680	0.133000	3.54e-02	2.54e-02
Glycosaminoglycan metabolism	59	1.34e-02	1.28e-01	0.2670	2.32e-02	0.044400	-1.59e-01	-1.81e-01	-0.104000	0.759000	0.55600	0.034400	1.65e-02	1.68e-01
Hh mutants abrogate ligand secretion	48	1.37e-02	1.29e-01	0.3240	-1.25e-01	-0.086200	3.37e-02	2.04e-01	0.197000	0.136000	0.30200	0.686000	1.45e-02	1.82e-02
TICAM1-dependent activation of IRF3/IRF7	12	1.38e-02	1.29e-01	0.6580	-4.17e-02	0.156000	-1.24e-01	4.87e-01	0.394000	0.803000	0.35100	0.458000	3.51e-03	1.82e-02
RAF activation	27	1.38e-02	1.29e-01	0.4390	1.99e-01	0.310000	4.73e-02	-4.90e-02	-0.229000	0.073000	0.00533	0.671000	6.60e-01	3.93e-02
HIV Infection	177	1.39e-02	1.29e-01	0.1730	-2.99e-02	-0.072200	5.77e-02	1.13e-01	0.088400	0.494000	0.09910	0.188000	1.01e-02	4.36e-02
UCH proteinases	69	1.41e-02	1.30e-01	0.3050	-1.25e-02	-0.141000	2.00e-02	1.94e-01	0.187000	0.858000	0.04270	0.774000	5.49e-03	7.38e-03
NIK–>noncanonical NF-kB signaling	49	1.43e-02	1.31e-01	0.3310	-3.96e-02	-0.141000	6.06e-02	1.54e-01	0.246000	0.632000	0.08800	0.464000	6.20e-02	2.90e-03
COPII-mediated vesicle transport	47	1.46e-02	1.32e-01	0.3120	-2.12e-01	-0.206000	-3.79e-02	8.90e-02	0.022200	0.012100	0.01470	0.654000	2.92e-01	7.93e-01
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	58	1.48e-02	1.33e-01	0.3320	3.74e-02	-0.132000	2.14e-02	2.35e-01	0.190000	0.622000	0.08280	0.778000	2.03e-03	1.24e-02
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	59	1.50e-02	1.34e-01	0.3250	3.11e-02	-0.136000	2.50e-02	2.33e-01	0.176000	0.680000	0.07180	0.740000	1.96e-03	1.95e-02
Mitochondrial translation termination	80	1.56e-02	1.37e-01	0.2740	-1.20e-02	-0.070000	1.43e-02	2.10e-01	0.160000	0.853000	0.28000	0.825000	1.20e-03	1.35e-02
Cellular response to starvation	107	1.56e-02	1.37e-01	0.2080	3.97e-02	-0.082900	7.52e-02	1.48e-01	0.084400	0.479000	0.14000	0.180000	8.44e-03	1.33e-01
APC/C:Cdc20 mediated degradation of mitotic proteins	61	1.60e-02	1.39e-01	0.3120	8.13e-03	-0.141000	3.35e-02	2.23e-01	0.162000	0.913000	0.05790	0.652000	2.58e-03	2.90e-02
Hedgehog ligand biogenesis	51	1.61e-02	1.39e-01	0.2960	-1.27e-01	-0.048600	3.10e-02	1.92e-01	0.176000	0.116000	0.54900	0.702000	1.76e-02	2.97e-02
Dectin-1 mediated noncanonical NF-kB signaling	50	1.64e-02	1.40e-01	0.3330	-2.13e-02	-0.136000	4.69e-02	1.69e-01	0.247000	0.795000	0.09780	0.566000	3.89e-02	2.50e-03
NOTCH2 Activation and Transmission of Signal to the Nucleus	12	1.66e-02	1.41e-01	0.6590	-6.31e-02	-0.065000	-1.67e-01	5.50e-01	0.310000	0.705000	0.69700	0.318000	9.67e-04	6.33e-02
Processing of Capped Intronless Pre-mRNA	21	1.67e-02	1.41e-01	0.4450	-2.70e-01	0.039700	3.18e-01	1.26e-01	-0.084200	0.032300	0.75300	0.011700	3.18e-01	5.04e-01
ADORA2B mediated anti-inflammatory cytokines production	30	1.71e-02	1.43e-01	0.3940	-1.26e-01	0.166000	-1.08e-01	-2.67e-01	-0.169000	0.232000	0.11500	0.307000	1.14e-02	1.09e-01
G1/S Transition	106	1.80e-02	1.46e-01	0.1990	-6.79e-03	-0.039900	1.12e-01	1.19e-01	0.105000	0.904000	0.48000	0.047200	3.45e-02	6.15e-02
Deactivation of the beta-catenin transactivating complex	27	1.80e-02	1.46e-01	0.4350	-1.06e-01	-0.050500	-8.17e-02	2.51e-01	0.325000	0.339000	0.65000	0.463000	2.42e-02	3.50e-03
Mitochondrial translation initiation	81	1.81e-02	1.46e-01	0.2710	-6.61e-04	-0.067500	1.92e-02	2.04e-01	0.165000	0.992000	0.29500	0.765000	1.57e-03	1.07e-02
Mitotic G1 phase and G1/S transition	121	1.82e-02	1.46e-01	0.1850	1.44e-02	-0.039300	1.02e-01	1.08e-01	0.102000	0.785000	0.45700	0.053100	4.14e-02	5.40e-02
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	60	1.82e-02	1.46e-01	0.3110	4.31e-02	-0.119000	3.52e-02	2.29e-01	0.164000	0.564000	0.11100	0.638000	2.15e-03	2.83e-02
Regulation of TP53 Activity through Phosphorylation	74	1.83e-02	1.46e-01	0.2580	-1.24e-01	-0.176000	9.20e-02	1.06e-01	0.024200	0.065700	0.00909	0.172000	1.15e-01	7.19e-01
Vpu mediated degradation of CD4	43	1.84e-02	1.46e-01	0.3580	-4.75e-02	-0.206000	7.36e-02	1.93e-01	0.202000	0.591000	0.01960	0.404000	2.90e-02	2.21e-02
Processive synthesis on the C-strand of the telomere	17	1.85e-02	1.46e-01	0.5460	-3.72e-01	-0.084900	1.23e-01	-8.34e-02	-0.362000	0.007920	0.54500	0.381000	5.52e-01	9.86e-03
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	51	1.85e-02	1.46e-01	0.3060	-8.46e-02	-0.147000	1.35e-01	1.72e-01	0.131000	0.297000	0.06980	0.096300	3.43e-02	1.06e-01
SARS-CoV Infections	109	1.91e-02	1.49e-01	0.1810	-1.36e-03	-0.041700	1.76e-01	1.28e-02	-0.007280	0.980000	0.45300	0.001570	8.18e-01	8.96e-01
Late Phase of HIV Life Cycle	105	1.93e-02	1.49e-01	0.2240	-1.96e-02	-0.046700	4.23e-02	1.62e-01	0.140000	0.729000	0.41000	0.455000	4.16e-03	1.37e-02
Removal of the Flap Intermediate from the C-strand	15	1.94e-02	1.49e-01	0.6000	-4.40e-01	-0.162000	1.64e-01	-7.22e-02	-0.329000	0.003170	0.27600	0.272000	6.29e-01	2.75e-02
Asparagine N-linked glycosylation	214	1.94e-02	1.49e-01	0.1480	-8.04e-02	-0.081000	1.63e-02	8.24e-02	0.041600	0.043900	0.04230	0.684000	3.88e-02	2.97e-01
Regulation of FZD by ubiquitination	12	1.95e-02	1.49e-01	0.6360	2.94e-01	-0.112000	-5.02e-01	-5.19e-02	0.224000	0.078000	0.50100	0.002600	7.56e-01	1.79e-01
BMAL1:CLOCK,NPAS2 activates circadian gene expression	14	2.02e-02	1.52e-01	0.5430	1.06e-01	0.498000	1.03e-01	-1.55e-01	0.025200	0.491000	0.00127	0.505000	3.14e-01	8.70e-01
Asymmetric localization of PCP proteins	51	2.02e-02	1.52e-01	0.3290	-7.70e-03	-0.177000	5.87e-02	1.99e-01	0.184000	0.924000	0.02860	0.469000	1.43e-02	2.35e-02
Resolution of Sister Chromatid Cohesion	90	2.07e-02	1.54e-01	0.2040	-1.08e-01	-0.011100	1.23e-01	1.08e-01	0.056200	0.078200	0.85600	0.044900	7.77e-02	3.58e-01
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	47	2.08e-02	1.54e-01	0.3210	5.13e-02	-0.072600	1.02e-01	2.28e-01	0.181000	0.543000	0.39000	0.225000	6.99e-03	3.19e-02
Regulation of APC/C activators between G1/S and early anaphase	66	2.15e-02	1.58e-01	0.2990	6.08e-02	-0.119000	2.23e-02	2.07e-01	0.168000	0.394000	0.09420	0.754000	3.72e-03	1.83e-02
Integrin cell surface interactions	23	2.16e-02	1.58e-01	0.4390	-5.96e-02	0.003720	9.15e-02	-4.08e-01	-0.121000	0.621000	0.97500	0.448000	7.16e-04	3.17e-01
ER Quality Control Compartment (ERQC)	18	2.22e-02	1.61e-01	0.5390	-1.10e-01	-0.093500	-2.18e-01	3.42e-01	0.325000	0.419000	0.49300	0.109000	1.21e-02	1.72e-02
ABC transporter disorders	56	2.23e-02	1.61e-01	0.3050	-1.09e-01	-0.154000	3.37e-02	1.66e-01	0.169000	0.159000	0.04610	0.663000	3.15e-02	2.91e-02
Switching of origins to a post-replicative state	70	2.27e-02	1.62e-01	0.2770	8.38e-02	-0.098100	4.09e-02	1.86e-01	0.155000	0.226000	0.15700	0.554000	7.23e-03	2.53e-02
Cytochrome c-mediated apoptotic response	10	2.28e-02	1.62e-01	0.4900	-2.82e-01	0.274000	-8.98e-02	2.50e-01	0.124000	0.123000	0.13400	0.623000	1.71e-01	4.96e-01
Carboxyterminal post-translational modifications of tubulin	19	2.30e-02	1.62e-01	0.4440	2.48e-01	0.177000	-2.12e-01	2.08e-01	-0.128000	0.061400	0.18200	0.109000	1.17e-01	3.34e-01
RHO GTPases activate PKNs	26	2.30e-02	1.62e-01	0.4790	-5.38e-02	0.269000	2.30e-01	-2.67e-01	-0.175000	0.635000	0.01760	0.042900	1.85e-02	1.24e-01
APC/C:Cdc20 mediated degradation of Securin	54	2.32e-02	1.62e-01	0.3290	2.71e-02	-0.137000	1.81e-02	2.37e-01	0.178000	0.731000	0.08210	0.819000	2.58e-03	2.37e-02
Synthesis of Leukotrienes (LT) and Eoxins (EX)	10	2.34e-02	1.62e-01	0.5740	3.38e-02	-0.184000	-4.63e-01	-2.66e-01	-0.097400	0.853000	0.31400	0.011300	1.45e-01	5.94e-01
NRIF signals cell death from the nucleus	13	2.35e-02	1.62e-01	0.5830	-1.01e-01	-0.109000	-2.71e-01	4.40e-01	0.226000	0.529000	0.49600	0.091100	6.04e-03	1.59e-01
RORA activates gene expression	10	2.35e-02	1.62e-01	0.6990	3.27e-01	0.596000	-4.62e-02	3.95e-02	0.153000	0.073500	0.00110	0.800000	8.29e-01	4.01e-01
PI3K/AKT Signaling in Cancer	50	2.37e-02	1.62e-01	0.4050	-1.93e-01	0.046200	1.27e-01	-2.59e-01	-0.204000	0.018500	0.57200	0.120000	1.58e-03	1.28e-02
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	62	2.39e-02	1.62e-01	0.3000	6.80e-03	-0.129000	2.66e-02	2.18e-01	0.158000	0.926000	0.07870	0.718000	3.07e-03	3.14e-02
Extracellular matrix organization	75	2.40e-02	1.62e-01	0.2710	1.66e-02	0.036500	4.31e-03	-2.08e-01	-0.169000	0.804000	0.58500	0.949000	1.90e-03	1.15e-02
Transport of Mature mRNA derived from an Intron-Containing Transcript	45	2.52e-02	1.69e-01	0.2780	-1.25e-01	0.010600	1.28e-01	1.72e-01	0.125000	0.147000	0.90300	0.139000	4.61e-02	1.48e-01
Muscle contraction	64	2.54e-02	1.69e-01	0.2430	2.17e-02	0.072300	1.62e-02	-2.23e-01	-0.056300	0.764000	0.31800	0.823000	2.05e-03	4.37e-01
HDACs deacetylate histones	26	2.60e-02	1.73e-01	0.4640	2.00e-02	0.114000	2.88e-01	-2.61e-01	-0.226000	0.860000	0.31500	0.011100	2.13e-02	4.60e-02
SARS-CoV-2 Infection	54	2.70e-02	1.78e-01	0.2560	-5.56e-02	-0.066700	1.77e-01	1.57e-01	0.046900	0.481000	0.39700	0.024500	4.65e-02	5.51e-01
Transport of Mature Transcript to Cytoplasm	54	2.77e-02	1.79e-01	0.2490	-1.61e-01	0.040900	1.57e-01	8.31e-02	0.053400	0.041200	0.60400	0.046600	2.92e-01	4.98e-01
Ubiquitin-dependent degradation of Cyclin D	43	2.77e-02	1.79e-01	0.3360	-6.58e-02	-0.155000	8.84e-02	2.01e-01	0.191000	0.456000	0.07840	0.317000	2.29e-02	3.02e-02
Protein-protein interactions at synapses	31	2.77e-02	1.79e-01	0.3430	1.70e-01	0.037400	-1.74e-01	-1.84e-01	-0.153000	0.102000	0.71900	0.094000	7.66e-02	1.42e-01
SCF-beta-TrCP mediated degradation of Emi1	46	2.78e-02	1.79e-01	0.3340	1.06e-02	-0.128000	6.62e-02	2.03e-01	0.222000	0.902000	0.13400	0.438000	1.73e-02	9.30e-03
DNA Double-Strand Break Repair	106	2.81e-02	1.80e-01	0.1790	-1.44e-01	-0.054300	2.58e-02	8.33e-02	0.029200	0.010500	0.33600	0.647000	1.40e-01	6.05e-01
TICAM1, RIP1-mediated IKK complex recruitment	17	3.07e-02	1.94e-01	0.4720	-3.34e-01	-0.190000	-2.90e-03	1.98e-01	0.190000	0.017300	0.17600	0.983000	1.57e-01	1.76e-01
Cellular response to hypoxia	58	3.09e-02	1.94e-01	0.2710	-2.38e-02	-0.111000	1.11e-01	1.79e-01	0.128000	0.755000	0.14600	0.144000	1.88e-02	9.28e-02
Translation initiation complex formation	46	3.10e-02	1.94e-01	0.3170	3.96e-02	-0.092400	9.17e-02	2.22e-01	0.182000	0.642000	0.27900	0.282000	9.37e-03	3.33e-02
Formation of the ternary complex, and subsequently, the 43S complex	39	3.10e-02	1.94e-01	0.3510	-1.76e-03	-0.139000	9.10e-02	2.23e-01	0.214000	0.985000	0.13500	0.326000	1.62e-02	2.06e-02
Intracellular signaling by second messengers	197	3.11e-02	1.94e-01	0.1880	-8.65e-02	-0.007160	9.13e-02	-1.25e-01	-0.061100	0.037400	0.86300	0.028000	2.55e-03	1.41e-01
Nuclear Envelope (NE) Reassembly	56	3.26e-02	2.02e-01	0.2510	1.93e-02	0.032200	1.34e-01	1.74e-01	0.116000	0.803000	0.67700	0.082500	2.48e-02	1.33e-01
Triglyceride metabolism	16	3.30e-02	2.04e-01	0.5170	8.06e-02	0.328000	-1.81e-01	-1.86e-01	-0.294000	0.577000	0.02340	0.211000	1.97e-01	4.19e-02
SARS-CoV-1 Infection	41	3.37e-02	2.07e-01	0.2870	-5.43e-02	-0.042700	2.22e-01	1.46e-01	0.085400	0.548000	0.63600	0.014200	1.07e-01	3.45e-01
Disorders of transmembrane transporters	102	3.42e-02	2.08e-01	0.2080	-7.47e-02	-0.075100	4.28e-02	1.19e-01	0.127000	0.194000	0.19100	0.456000	3.88e-02	2.70e-02
Ion homeostasis	25	3.43e-02	2.08e-01	0.3920	2.15e-01	0.176000	-1.28e-02	-2.43e-01	-0.131000	0.062800	0.12800	0.912000	3.52e-02	2.56e-01
Degradation of DVL	47	3.54e-02	2.14e-01	0.3110	-1.10e-01	-0.161000	7.41e-02	1.42e-01	0.182000	0.193000	0.05660	0.380000	9.31e-02	3.09e-02
Vif-mediated degradation of APOBEC3G	42	3.61e-02	2.17e-01	0.3280	-1.02e-01	-0.168000	9.84e-02	1.72e-01	0.171000	0.252000	0.06000	0.270000	5.34e-02	5.55e-02
IKK complex recruitment mediated by RIP1	17	3.66e-02	2.19e-01	0.4760	-3.63e-01	-0.261000	-2.67e-02	1.16e-01	0.111000	0.009510	0.06250	0.849000	4.06e-01	4.27e-01
Processing of Intronless Pre-mRNAs	14	3.68e-02	2.19e-01	0.6100	-4.71e-01	-0.042500	3.61e-01	-5.68e-02	-0.126000	0.002310	0.78300	0.019500	7.13e-01	4.14e-01
S Phase	128	3.79e-02	2.24e-01	0.1750	2.65e-03	-0.084500	8.05e-02	9.94e-02	0.084500	0.959000	0.10000	0.117000	5.30e-02	9.99e-02
Hemostasis	292	3.83e-02	2.24e-01	0.1210	2.97e-02	0.029300	-6.14e-04	-9.73e-02	-0.059200	0.386000	0.39300	0.986000	4.57e-03	8.45e-02
Chromatin modifying enzymes	137	3.86e-02	2.24e-01	0.1490	-5.38e-03	0.018900	1.47e-01	-4.96e-03	0.013900	0.914000	0.70300	0.003030	9.20e-01	7.79e-01
Chromatin organization	137	3.86e-02	2.24e-01	0.1490	-5.38e-03	0.018900	1.47e-01	-4.96e-03	0.013900	0.914000	0.70300	0.003030	9.20e-01	7.79e-01
Chaperonin-mediated protein folding	52	3.86e-02	2.24e-01	0.2560	-6.55e-02	-0.123000	1.47e-01	1.55e-01	0.024100	0.414000	0.12600	0.067500	5.28e-02	7.64e-01
Mitochondrial calcium ion transport	13	3.88e-02	2.24e-01	0.5060	3.73e-01	0.201000	1.13e-01	2.49e-01	-0.043200	0.019900	0.20900	0.482000	1.20e-01	7.87e-01
Netrin-1 signaling	24	3.97e-02	2.27e-01	0.3170	3.04e-02	-0.091600	4.16e-03	-3.02e-01	-0.008710	0.797000	0.43800	0.972000	1.05e-02	9.41e-01
Signaling by Erythropoietin	19	3.98e-02	2.27e-01	0.5130	3.01e-01	0.383000	-1.08e-01	1.20e-01	-0.020800	0.023300	0.00390	0.414000	3.66e-01	8.75e-01
Signaling by ERBB2	31	4.06e-02	2.31e-01	0.2910	-1.84e-01	-0.086300	-1.39e-02	-3.78e-02	0.204000	0.075800	0.40600	0.893000	7.16e-01	4.98e-02
Heme signaling	25	4.10e-02	2.31e-01	0.4070	1.60e-01	0.362000	-5.08e-02	-6.35e-02	0.041800	0.166000	0.00173	0.661000	5.83e-01	7.18e-01
Signaling by WNT in cancer	23	4.18e-02	2.31e-01	0.4030	3.33e-01	0.011100	-2.12e-01	-6.03e-02	0.053200	0.005680	0.92700	0.078200	6.17e-01	6.59e-01
Long-term potentiation	10	4.19e-02	2.31e-01	0.5870	3.47e-01	0.096700	-3.76e-01	-1.30e-01	-0.236000	0.057400	0.59600	0.039400	4.75e-01	1.97e-01
SUMOylation of DNA methylation proteins	14	4.19e-02	2.31e-01	0.5220	-2.06e-02	0.220000	-2.40e-02	-4.50e-01	-0.145000	0.894000	0.15400	0.877000	3.56e-03	3.47e-01
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	10	4.21e-02	2.31e-01	0.6390	-2.38e-01	-0.416000	-1.18e-01	8.70e-02	0.397000	0.194000	0.02270	0.519000	6.34e-01	2.98e-02
Autodegradation of Cdh1 by Cdh1:APC/C	52	4.22e-02	2.31e-01	0.3160	3.79e-02	-0.115000	2.88e-02	2.18e-01	0.192000	0.637000	0.15300	0.720000	6.68e-03	1.68e-02
SUMO E3 ligases SUMOylate target proteins	130	4.22e-02	2.31e-01	0.1570	-3.47e-02	0.006230	9.99e-02	8.79e-02	0.075500	0.496000	0.90300	0.050100	8.45e-02	1.38e-01
Ribosomal scanning and start codon recognition	46	4.24e-02	2.31e-01	0.3110	4.69e-02	-0.088500	8.07e-02	2.09e-01	0.191000	0.583000	0.30000	0.344000	1.41e-02	2.52e-02
HATs acetylate histones	53	4.27e-02	2.32e-01	0.2810	-1.14e-01	0.105000	2.28e-01	-3.14e-02	-0.043000	0.153000	0.18600	0.004160	6.93e-01	5.89e-01
Transcriptional regulation of granulopoiesis	24	4.39e-02	2.37e-01	0.3730	1.44e-01	-0.090300	-3.16e-01	-9.71e-02	0.029100	0.221000	0.44400	0.007340	4.10e-01	8.05e-01
AUF1 (hnRNP D0) binds and destabilizes mRNA	45	4.45e-02	2.39e-01	0.3070	-7.49e-02	-0.134000	9.65e-02	1.78e-01	0.171000	0.385000	0.12100	0.263000	3.86e-02	4.72e-02
Activation of ATR in response to replication stress	29	4.48e-02	2.40e-01	0.2910	6.10e-02	-0.052600	1.87e-01	2.06e-01	-0.019900	0.570000	0.62400	0.081100	5.48e-02	8.53e-01
ABC-family proteins mediated transport	71	4.60e-02	2.45e-01	0.2500	-9.33e-02	-0.136000	4.14e-02	1.35e-01	0.124000	0.175000	0.04720	0.547000	4.99e-02	7.17e-02
HIV Life Cycle	117	4.69e-02	2.49e-01	0.1990	-1.43e-02	-0.056500	2.57e-02	1.47e-01	0.119000	0.791000	0.29300	0.632000	6.17e-03	2.71e-02
ER to Golgi Anterograde Transport	101	4.72e-02	2.49e-01	0.1980	-1.53e-01	-0.117000	1.86e-02	4.10e-02	0.011600	0.007930	0.04340	0.747000	4.78e-01	8.41e-01
Metabolism of non-coding RNA	43	4.75e-02	2.49e-01	0.2780	-4.83e-03	-0.010600	1.09e-01	2.34e-01	0.102000	0.956000	0.90400	0.216000	7.88e-03	2.49e-01
snRNP Assembly	43	4.75e-02	2.49e-01	0.2780	-4.83e-03	-0.010600	1.09e-01	2.34e-01	0.102000	0.956000	0.90400	0.216000	7.88e-03	2.49e-01
APC-Cdc20 mediated degradation of Nek2A	21	4.80e-02	2.50e-01	0.5140	1.97e-01	-0.071200	-1.88e-01	3.92e-01	0.176000	0.119000	0.57300	0.136000	1.86e-03	1.63e-01
PTEN Regulation	105	4.82e-02	2.50e-01	0.1930	-8.46e-02	-0.090700	1.40e-01	4.06e-03	0.044900	0.135000	0.10900	0.013300	9.43e-01	4.28e-01
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	45	4.86e-02	2.50e-01	0.3010	-4.58e-02	-0.156000	1.08e-01	1.57e-01	0.168000	0.595000	0.07140	0.211000	6.91e-02	5.10e-02
DNA Damage Recognition in GG-NER	35	4.87e-02	2.50e-01	0.3810	-9.74e-03	-0.067500	-5.42e-02	2.97e-01	0.222000	0.921000	0.49000	0.579000	2.38e-03	2.34e-02
Degradation of beta-catenin by the destruction complex	67	4.89e-02	2.50e-01	0.2510	4.81e-03	-0.096000	5.80e-02	1.31e-01	0.182000	0.946000	0.17500	0.413000	6.32e-02	1.01e-02
Regulation of PTEN stability and activity	55	4.94e-02	2.51e-01	0.2720	-6.33e-02	-0.127000	9.67e-02	1.48e-01	0.151000	0.418000	0.10500	0.216000	5.76e-02	5.35e-02
Downregulation of ERBB2 signaling	15	4.95e-02	2.51e-01	0.4670	-2.86e-01	-0.212000	-1.29e-01	6.21e-02	0.266000	0.054900	0.15600	0.387000	6.77e-01	7.51e-02
Metalloprotease DUBs	16	5.00e-02	2.52e-01	0.5470	-5.47e-02	-0.160000	-7.85e-02	2.72e-01	0.436000	0.705000	0.26900	0.587000	5.97e-02	2.51e-03
Neurexins and neuroligins	20	5.02e-02	2.52e-01	0.3860	2.02e-01	0.039500	-2.00e-01	-2.44e-01	-0.083000	0.117000	0.76000	0.122000	5.86e-02	5.21e-01
Calnexin/calreticulin cycle	23	5.11e-02	2.53e-01	0.4310	-7.20e-02	-0.087200	-1.62e-01	3.18e-01	0.214000	0.550000	0.46900	0.179000	8.25e-03	7.62e-02
Vasopressin regulates renal water homeostasis via Aquaporins	18	5.12e-02	2.53e-01	0.4030	-7.76e-02	0.356000	-1.24e-01	-1.01e-01	-0.066500	0.569000	0.00898	0.362000	4.60e-01	6.25e-01
Degradation of AXIN	46	5.13e-02	2.53e-01	0.3220	-1.50e-03	-0.103000	3.31e-02	2.04e-01	0.225000	0.986000	0.22600	0.698000	1.69e-02	8.36e-03
Degradation of GLI2 by the proteasome	49	5.17e-02	2.53e-01	0.2900	-4.09e-02	-0.162000	8.97e-02	1.40e-01	0.169000	0.621000	0.05010	0.278000	8.98e-02	4.11e-02
GLI3 is processed to GLI3R by the proteasome	49	5.17e-02	2.53e-01	0.2900	-4.09e-02	-0.162000	8.97e-02	1.40e-01	0.169000	0.621000	0.05010	0.278000	8.98e-02	4.11e-02
CDK-mediated phosphorylation and removal of Cdc6	58	5.18e-02	2.53e-01	0.2850	4.95e-02	-0.116000	3.67e-02	1.89e-01	0.168000	0.515000	0.12600	0.629000	1.28e-02	2.69e-02
Diseases associated with O-glycosylation of proteins	20	5.19e-02	2.53e-01	0.3570	1.69e-01	0.057800	-2.33e-01	1.34e-01	-0.153000	0.192000	0.65500	0.071000	2.99e-01	2.36e-01
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	34	5.24e-02	2.54e-01	0.3690	-1.13e-01	-0.242000	1.35e-02	1.73e-01	0.185000	0.253000	0.01450	0.892000	8.05e-02	6.17e-02
Adaptive Immune System	451	5.25e-02	2.54e-01	0.0792	4.78e-02	0.034800	4.76e-02	-1.99e-02	-0.010800	0.086100	0.21200	0.087000	4.74e-01	6.98e-01
Signaling by NOTCH2	18	5.34e-02	2.57e-01	0.4990	-1.44e-02	-0.082700	-9.15e-02	4.19e-01	0.240000	0.916000	0.54400	0.502000	2.08e-03	7.85e-02
DNA Replication	101	5.40e-02	2.59e-01	0.2020	1.71e-02	-0.091800	5.69e-02	1.32e-01	0.107000	0.768000	0.11200	0.324000	2.28e-02	6.42e-02
SUMOylation	135	5.44e-02	2.60e-01	0.1500	-1.55e-02	0.009640	9.48e-02	8.49e-02	0.076500	0.757000	0.84700	0.058100	8.99e-02	1.26e-01
Glucagon signaling in metabolic regulation	16	5.47e-02	2.60e-01	0.4430	-3.85e-02	0.351000	-1.74e-01	-1.83e-01	-0.085200	0.790000	0.01510	0.228000	2.05e-01	5.55e-01
Interleukin-4 and Interleukin-13 signaling	47	5.57e-02	2.64e-01	0.3440	-3.63e-02	0.002790	2.00e-01	-1.99e-01	-0.193000	0.668000	0.97400	0.017900	1.82e-02	2.19e-02
The NLRP3 inflammasome	12	5.69e-02	2.68e-01	0.6450	1.88e-03	-0.408000	-2.59e-01	3.27e-01	0.275000	0.991000	0.01450	0.120000	5.02e-02	9.94e-02
Platelet calcium homeostasis	17	5.74e-02	2.69e-01	0.4250	-1.44e-02	0.084200	-5.18e-02	-4.01e-01	-0.096200	0.918000	0.54800	0.712000	4.18e-03	4.93e-01
Potential therapeutics for SARS	56	5.81e-02	2.71e-01	0.2210	6.25e-02	-0.032800	1.52e-01	-1.21e-01	-0.076700	0.419000	0.67200	0.048900	1.19e-01	3.21e-01
Cyclin E associated events during G1/S transition	70	5.82e-02	2.71e-01	0.2410	-2.25e-03	-0.107000	6.39e-02	1.32e-01	0.159000	0.974000	0.12300	0.356000	5.74e-02	2.13e-02
PIP3 activates AKT signaling	172	5.86e-02	2.72e-01	0.1780	-9.48e-02	-0.020500	1.18e-01	-8.57e-02	-0.032400	0.032800	0.64500	0.007890	5.36e-02	4.66e-01
Generation of second messenger molecules	16	5.92e-02	2.74e-01	0.4970	1.93e-01	0.200000	1.47e-01	-2.26e-01	-0.311000	0.181000	0.16600	0.307000	1.18e-01	3.11e-02
Diseases associated with glycosaminoglycan metabolism	15	5.96e-02	2.74e-01	0.4910	-1.77e-02	0.135000	-9.06e-02	-4.25e-01	-0.183000	0.906000	0.36500	0.544000	4.35e-03	2.20e-01
RNA polymerase II transcribes snRNA genes	62	6.21e-02	2.83e-01	0.2360	-1.06e-01	-0.075600	1.07e-01	1.21e-01	0.112000	0.149000	0.30400	0.145000	9.95e-02	1.26e-01
Activation of NF-kappaB in B cells	54	6.21e-02	2.83e-01	0.2670	-3.63e-02	-0.141000	9.64e-02	1.35e-01	0.149000	0.645000	0.07250	0.221000	8.62e-02	5.90e-02
Nicotinate metabolism	16	6.22e-02	2.83e-01	0.4620	-5.85e-02	-0.289000	1.78e-01	-1.18e-01	-0.284000	0.686000	0.04570	0.217000	4.15e-01	4.91e-02
RHOC GTPase cycle	45	6.26e-02	2.83e-01	0.2170	3.23e-02	0.115000	1.44e-01	-9.25e-02	0.062900	0.708000	0.18400	0.096100	2.83e-01	4.66e-01
Protein folding	58	6.33e-02	2.85e-01	0.2290	-6.20e-02	-0.116000	1.39e-01	1.25e-01	0.004180	0.415000	0.12800	0.067700	9.94e-02	9.56e-01
Formation of TC-NER Pre-Incision Complex	45	6.42e-02	2.88e-01	0.3130	4.02e-02	-0.210000	-1.49e-02	1.85e-01	0.133000	0.641000	0.01470	0.863000	3.20e-02	1.24e-01
Meiotic recombination	19	6.49e-02	2.90e-01	0.4250	-3.36e-01	-0.104000	1.95e-01	8.87e-02	-0.107000	0.011300	0.43500	0.142000	5.04e-01	4.21e-01
Aquaporin-mediated transport	19	6.53e-02	2.91e-01	0.3920	-3.52e-02	0.331000	-1.49e-01	-1.32e-01	-0.056400	0.791000	0.01250	0.260000	3.19e-01	6.70e-01
DNA Damage Bypass	40	6.59e-02	2.91e-01	0.3290	-1.02e-01	-0.199000	8.00e-03	1.79e-01	0.162000	0.266000	0.02950	0.930000	5.06e-02	7.69e-02
Inactivation of APC/C via direct inhibition of the APC/C complex	16	6.61e-02	2.91e-01	0.5210	3.42e-01	-0.010000	-1.79e-01	3.41e-01	0.081200	0.018000	0.94500	0.215000	1.82e-02	5.74e-01
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	16	6.61e-02	2.91e-01	0.5210	3.42e-01	-0.010000	-1.79e-01	3.41e-01	0.081200	0.018000	0.94500	0.215000	1.82e-02	5.74e-01
Homology Directed Repair	84	6.80e-02	2.98e-01	0.1820	-1.47e-01	-0.050300	3.44e-02	8.40e-02	0.024000	0.020200	0.42600	0.587000	1.84e-01	7.04e-01
Gene expression (Transcription)	958	6.81e-02	2.98e-01	0.0635	-3.81e-02	-0.025200	2.98e-02	1.92e-02	0.026200	0.052400	0.20000	0.129000	3.27e-01	1.81e-01
Chondroitin sulfate/dermatan sulfate metabolism	26	6.85e-02	2.98e-01	0.3610	2.03e-01	0.138000	-1.29e-01	-1.91e-01	-0.128000	0.072900	0.22400	0.255000	9.16e-02	2.59e-01
Meiotic synapsis	22	6.92e-02	3.00e-01	0.4130	-1.65e-01	-0.308000	7.46e-02	-6.38e-02	-0.196000	0.180000	0.01240	0.545000	6.04e-01	1.12e-01
ROS sensing by NFE2L2	47	6.94e-02	3.00e-01	0.2840	-8.54e-02	-0.152000	1.03e-01	1.44e-01	0.137000	0.312000	0.07100	0.222000	8.72e-02	1.06e-01
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	32	7.00e-02	3.02e-01	0.4120	5.19e-02	-0.077000	-8.26e-02	3.10e-01	0.241000	0.612000	0.45200	0.419000	2.45e-03	1.83e-02
Circadian Clock	50	7.10e-02	3.04e-01	0.2690	9.22e-02	0.248000	-2.68e-02	-1.91e-02	0.032300	0.260000	0.00245	0.744000	8.15e-01	6.93e-01
Constitutive Signaling by AKT1 E17K in Cancer	23	7.20e-02	3.08e-01	0.4710	-2.74e-01	0.072800	1.88e-01	-2.95e-01	-0.138000	0.023000	0.54600	0.119000	1.42e-02	2.51e-01
Deadenylation of mRNA	22	7.32e-02	3.12e-01	0.3200	-5.03e-02	0.226000	4.51e-02	2.14e-01	0.025200	0.683000	0.06680	0.714000	8.21e-02	8.38e-01
Growth hormone receptor signaling	17	7.39e-02	3.13e-01	0.4680	4.97e-02	0.276000	1.59e-01	-7.40e-02	-0.331000	0.723000	0.04900	0.256000	5.97e-01	1.80e-02
Regulation of Apoptosis	44	7.41e-02	3.13e-01	0.3100	-5.26e-02	-0.129000	3.17e-02	1.93e-01	0.195000	0.547000	0.13900	0.716000	2.66e-02	2.52e-02
Stimuli-sensing channels	35	7.43e-02	3.13e-01	0.4090	1.08e-01	-0.012100	-2.42e-01	1.69e-01	0.262000	0.271000	0.90200	0.013400	8.32e-02	7.32e-03
Synthesis of DNA	94	7.63e-02	3.20e-01	0.2010	1.80e-02	-0.102000	5.17e-02	1.29e-01	0.101000	0.764000	0.08840	0.388000	3.08e-02	9.27e-02
Fatty acid metabolism	96	7.66e-02	3.20e-01	0.1790	8.44e-02	0.036700	-1.32e-01	-7.50e-02	-0.022700	0.154000	0.53500	0.025300	2.05e-01	7.02e-01
Disease	900	7.74e-02	3.22e-01	0.0566	1.01e-02	-0.004980	4.78e-02	-3.35e-03	-0.027900	0.618000	0.80500	0.017800	8.68e-01	1.66e-01
Cilium Assembly	134	7.77e-02	3.22e-01	0.1650	-7.73e-02	-0.092800	3.78e-02	5.05e-02	0.093800	0.124000	0.06470	0.452000	3.15e-01	6.17e-02
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	30	7.83e-02	3.23e-01	0.3240	9.29e-02	0.145000	1.27e-01	-2.25e-01	-0.089900	0.379000	0.16900	0.228000	3.30e-02	3.95e-01
Regulation of lipid metabolism by PPARalpha	83	7.86e-02	3.23e-01	0.2190	5.03e-02	0.038500	3.30e-02	1.54e-01	0.138000	0.429000	0.54500	0.604000	1.52e-02	3.01e-02
Cell surface interactions at the vascular wall	56	7.92e-02	3.23e-01	0.2110	1.07e-01	-0.009900	4.75e-02	-1.42e-01	-0.103000	0.168000	0.89800	0.539000	6.61e-02	1.81e-01
EML4 and NUDC in mitotic spindle formation	85	7.94e-02	3.23e-01	0.1670	-6.70e-02	0.007330	8.74e-02	1.24e-01	0.020600	0.287000	0.90700	0.165000	4.91e-02	7.43e-01
mRNA decay by 3’ to 5’ exoribonuclease	13	7.95e-02	3.23e-01	0.5820	-3.97e-01	-0.236000	3.53e-01	-9.37e-05	-0.021500	0.013200	0.14000	0.027600	1.00e+00	8.93e-01
Regulation of RUNX2 expression and activity	56	7.98e-02	3.23e-01	0.2400	-2.49e-02	-0.123000	1.20e-01	1.39e-01	0.090600	0.747000	0.11300	0.120000	7.28e-02	2.42e-01
Polo-like kinase mediated events	16	7.99e-02	3.23e-01	0.3980	-3.51e-02	0.180000	2.22e-01	2.37e-01	0.140000	0.808000	0.21300	0.125000	1.01e-01	3.33e-01
Prefoldin mediated transfer of substrate to CCT/TriC	16	8.05e-02	3.25e-01	0.4730	3.07e-02	-0.157000	-1.37e-02	4.14e-01	0.164000	0.832000	0.27800	0.925000	4.16e-03	2.57e-01
Interferon alpha/beta signaling	50	8.24e-02	3.31e-01	0.3180	-4.41e-02	-0.019500	1.86e-01	-1.85e-01	-0.174000	0.590000	0.81100	0.023400	2.41e-02	3.38e-02
Chaperone Mediated Autophagy	12	8.28e-02	3.31e-01	0.5490	-1.01e-01	-0.111000	-1.25e-01	2.29e-01	0.459000	0.544000	0.50400	0.455000	1.70e-01	5.86e-03
SCF(Skp2)-mediated degradation of p27/p21	51	8.36e-02	3.34e-01	0.2790	-1.19e-02	-0.128000	5.61e-02	1.67e-01	0.174000	0.884000	0.11300	0.489000	3.96e-02	3.21e-02
Metabolism of amino acids and derivatives	210	8.39e-02	3.34e-01	0.1360	1.89e-02	-0.046300	2.10e-02	1.07e-01	0.063600	0.639000	0.25000	0.602000	7.68e-03	1.14e-01
Transport of small molecules	322	8.47e-02	3.36e-01	0.1230	3.58e-02	0.044400	-6.76e-02	7.17e-02	0.046500	0.273000	0.17400	0.038800	2.85e-02	1.56e-01
Cyclin A:Cdk2-associated events at S phase entry	72	8.57e-02	3.38e-01	0.2150	4.03e-04	-0.088000	7.83e-02	1.09e-01	0.144000	0.995000	0.19800	0.251000	1.10e-01	3.54e-02
Regulation of ornithine decarboxylase (ODC)	42	8.61e-02	3.39e-01	0.2760	-8.16e-02	-0.139000	1.73e-01	1.11e-01	0.090000	0.361000	0.12000	0.053000	2.15e-01	3.14e-01
Translesion synthesis by POLK	15	8.70e-02	3.41e-01	0.4710	-2.16e-01	-0.177000	1.12e-01	2.26e-01	0.283000	0.147000	0.23600	0.454000	1.30e-01	5.74e-02
Cellular response to chemical stress	111	8.75e-02	3.42e-01	0.1970	5.70e-02	0.055000	2.94e-03	1.33e-01	0.122000	0.301000	0.31900	0.958000	1.61e-02	2.67e-02
Signaling by FLT3 ITD and TKD mutants	12	8.83e-02	3.44e-01	0.5350	1.28e-01	0.145000	-1.41e-01	-3.57e-01	-0.319000	0.444000	0.38600	0.397000	3.21e-02	5.59e-02
Mitotic Prophase	69	8.98e-02	3.48e-01	0.2280	-1.25e-01	-0.112000	1.43e-01	5.65e-02	-0.014900	0.073500	0.11000	0.039700	4.18e-01	8.31e-01
Membrane binding and targetting of GAG proteins	11	9.26e-02	3.56e-01	0.6100	-7.56e-02	-0.066700	-2.03e-01	3.80e-01	0.420000	0.664000	0.70200	0.244000	2.90e-02	1.59e-02
Synthesis And Processing Of GAG, GAGPOL Polyproteins	11	9.26e-02	3.56e-01	0.6100	-7.56e-02	-0.066700	-2.03e-01	3.80e-01	0.420000	0.664000	0.70200	0.244000	2.90e-02	1.59e-02
Regulation of RUNX3 expression and activity	48	9.29e-02	3.56e-01	0.2770	-2.66e-02	-0.107000	6.28e-02	1.95e-01	0.150000	0.751000	0.19900	0.452000	1.95e-02	7.26e-02
Nervous system development	294	9.29e-02	3.56e-01	0.0944	2.82e-02	-0.070400	2.99e-02	2.73e-02	0.039100	0.409000	0.03950	0.382000	4.25e-01	2.52e-01
Diseases of metabolism	119	9.34e-02	3.56e-01	0.1350	5.24e-02	-0.047100	-1.02e-01	1.32e-02	-0.052600	0.325000	0.37700	0.054800	8.05e-01	3.24e-01
Death Receptor Signalling	88	9.42e-02	3.58e-01	0.1410	-1.06e-01	0.041400	-3.50e-02	5.74e-02	0.049500	0.086100	0.50300	0.571000	3.53e-01	4.23e-01
Elevation of cytosolic Ca2+ levels	10	9.52e-02	3.60e-01	0.6340	-2.13e-01	0.204000	2.31e-02	-4.96e-01	-0.262000	0.243000	0.26400	0.899000	6.63e-03	1.51e-01
Regulation of TP53 Degradation	33	9.55e-02	3.60e-01	0.2980	-1.15e-01	-0.146000	3.08e-02	5.51e-02	0.224000	0.252000	0.14700	0.760000	5.84e-01	2.63e-02
Regulation of TP53 Activity through Acetylation	27	9.56e-02	3.60e-01	0.2830	2.90e-02	-0.002440	2.18e-01	-1.78e-01	-0.007410	0.795000	0.98300	0.050200	1.09e-01	9.47e-01
Regulation of HSF1-mediated heat shock response	62	9.72e-02	3.65e-01	0.2060	-1.63e-01	-0.052300	5.82e-02	9.14e-02	0.036400	0.026600	0.47700	0.429000	2.14e-01	6.21e-01
Cross-presentation of soluble exogenous antigens (endosomes)	37	9.80e-02	3.66e-01	0.3030	-3.69e-02	-0.174000	1.08e-01	1.48e-01	0.162000	0.698000	0.06720	0.256000	1.19e-01	8.77e-02
Degradation of the extracellular matrix	26	9.92e-02	3.66e-01	0.3640	-3.61e-02	0.020500	6.33e-02	-1.32e-01	-0.331000	0.750000	0.85600	0.576000	2.43e-01	3.50e-03
Signaling by Interleukins	256	9.92e-02	3.66e-01	0.1500	-4.12e-02	0.017900	8.78e-02	-6.43e-02	-0.092900	0.260000	0.62500	0.016400	7.87e-02	1.10e-02
Cyclin A/B1/B2 associated events during G2/M transition	22	1.00e-01	3.66e-01	0.3260	-4.49e-03	0.094400	2.53e-01	1.67e-01	0.076700	0.971000	0.44400	0.040200	1.76e-01	5.34e-01
Plasma lipoprotein clearance	19	1.01e-01	3.66e-01	0.4330	-1.92e-01	-0.299000	-8.75e-02	1.65e-01	0.162000	0.148000	0.02400	0.510000	2.12e-01	2.23e-01
Translation of structural proteins	26	1.01e-01	3.66e-01	0.2970	-2.68e-02	-0.055800	2.55e-01	1.17e-01	-0.076600	0.813000	0.62300	0.024300	3.04e-01	5.00e-01
HDR through Homologous Recombination (HRR)	54	1.01e-01	3.66e-01	0.2290	-1.57e-01	-0.107000	5.27e-02	1.13e-01	0.027100	0.045600	0.17400	0.504000	1.52e-01	7.31e-01
Inflammasomes	16	1.02e-01	3.66e-01	0.4170	-4.45e-03	-0.236000	-1.87e-01	2.85e-01	0.044500	0.975000	0.10200	0.196000	4.83e-02	7.58e-01
HIV Transcription Initiation	37	1.02e-01	3.66e-01	0.2770	3.97e-02	-0.242000	4.51e-02	6.56e-02	0.100000	0.677000	0.01090	0.635000	4.90e-01	2.92e-01
RNA Polymerase II HIV Promoter Escape	37	1.02e-01	3.66e-01	0.2770	3.97e-02	-0.242000	4.51e-02	6.56e-02	0.100000	0.677000	0.01090	0.635000	4.90e-01	2.92e-01
RNA Polymerase II Promoter Escape	37	1.02e-01	3.66e-01	0.2770	3.97e-02	-0.242000	4.51e-02	6.56e-02	0.100000	0.677000	0.01090	0.635000	4.90e-01	2.92e-01
RNA Polymerase II Transcription Initiation	37	1.02e-01	3.66e-01	0.2770	3.97e-02	-0.242000	4.51e-02	6.56e-02	0.100000	0.677000	0.01090	0.635000	4.90e-01	2.92e-01
RNA Polymerase II Transcription Initiation And Promoter Clearance	37	1.02e-01	3.66e-01	0.2770	3.97e-02	-0.242000	4.51e-02	6.56e-02	0.100000	0.677000	0.01090	0.635000	4.90e-01	2.92e-01
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	37	1.02e-01	3.66e-01	0.2770	3.97e-02	-0.242000	4.51e-02	6.56e-02	0.100000	0.677000	0.01090	0.635000	4.90e-01	2.92e-01
SHC1 events in ERBB2 signaling	10	1.02e-01	3.66e-01	0.4010	-1.57e-01	0.068700	3.41e-02	-3.29e-01	0.148000	0.389000	0.70700	0.852000	7.14e-02	4.18e-01
Synthesis of very long-chain fatty acyl-CoAs	12	1.03e-01	3.66e-01	0.4810	2.58e-01	0.351000	9.53e-02	-1.80e-01	-0.004820	0.121000	0.03510	0.568000	2.80e-01	9.77e-01
Transport of Mature mRNAs Derived from Intronless Transcripts	38	1.04e-01	3.69e-01	0.2560	-1.64e-01	0.054600	1.73e-01	4.69e-02	0.056200	0.080300	0.56100	0.064700	6.18e-01	5.49e-01
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	72	1.06e-01	3.74e-01	0.2090	-1.05e-01	-0.090100	1.44e-01	1.54e-02	0.060700	0.125000	0.18700	0.034700	8.21e-01	3.74e-01
RUNX2 regulates osteoblast differentiation	13	1.07e-01	3.79e-01	0.3880	-7.21e-02	-0.000078	-3.75e-01	4.30e-02	-0.049600	0.653000	1.00000	0.019100	7.89e-01	7.57e-01
Oxidative Stress Induced Senescence	51	1.08e-01	3.82e-01	0.1910	-6.85e-02	-0.060200	8.64e-02	-3.86e-02	0.138000	0.398000	0.45800	0.287000	6.34e-01	8.81e-02
Gluconeogenesis	24	1.09e-01	3.82e-01	0.3070	9.11e-03	-0.104000	-4.99e-02	-9.86e-02	-0.267000	0.938000	0.37900	0.673000	4.04e-01	2.37e-02
RNA Polymerase III Transcription Initiation	32	1.09e-01	3.82e-01	0.3300	-2.16e-01	-0.145000	1.48e-01	2.52e-02	-0.135000	0.034300	0.15700	0.148000	8.05e-01	1.85e-01
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	34	1.10e-01	3.82e-01	0.3250	-1.43e-01	0.001720	-5.40e-02	-1.91e-01	-0.214000	0.150000	0.98600	0.586000	5.46e-02	3.11e-02
Neddylation	172	1.10e-01	3.82e-01	0.1130	2.55e-02	-0.003120	8.99e-02	5.60e-02	0.030400	0.566000	0.94400	0.043000	2.08e-01	4.93e-01
Signaling by NOTCH3	30	1.11e-01	3.82e-01	0.3150	-4.76e-02	0.005290	5.21e-02	2.55e-01	0.172000	0.652000	0.96000	0.621000	1.58e-02	1.04e-01
Cell recruitment (pro-inflammatory response)	15	1.11e-01	3.82e-01	0.4970	3.36e-02	-0.314000	-2.30e-01	2.69e-01	0.149000	0.822000	0.03530	0.123000	7.12e-02	3.17e-01
Purinergic signaling in leishmaniasis infection	15	1.11e-01	3.82e-01	0.4970	3.36e-02	-0.314000	-2.30e-01	2.69e-01	0.149000	0.822000	0.03530	0.123000	7.12e-02	3.17e-01
E2F mediated regulation of DNA replication	12	1.12e-01	3.82e-01	0.3990	9.20e-02	0.168000	3.16e-01	-1.33e-01	0.073600	0.581000	0.31400	0.058200	4.26e-01	6.59e-01
Pexophagy	11	1.12e-01	3.82e-01	0.4900	-3.06e-01	-0.143000	-5.50e-02	2.46e-01	0.250000	0.078700	0.41100	0.752000	1.59e-01	1.51e-01
Transport of Mature mRNA Derived from an Intronless Transcript	37	1.12e-01	3.82e-01	0.2520	-1.68e-01	0.053100	1.63e-01	3.10e-02	0.070600	0.077200	0.57700	0.085800	7.45e-01	4.58e-01
Dopamine Neurotransmitter Release Cycle	10	1.12e-01	3.82e-01	0.5350	1.66e-01	0.149000	-4.73e-01	-1.12e-01	0.023600	0.364000	0.41600	0.009650	5.39e-01	8.97e-01
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	14	1.14e-01	3.87e-01	0.5890	-4.30e-01	-0.137000	3.04e-01	-1.89e-01	-0.124000	0.005400	0.37400	0.049000	2.20e-01	4.24e-01
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	14	1.15e-01	3.88e-01	0.5960	-4.28e-01	-0.129000	3.09e-01	-1.47e-01	-0.196000	0.005550	0.40500	0.045700	3.40e-01	2.03e-01
Defective pyroptosis	10	1.15e-01	3.88e-01	0.3700	-3.93e-02	0.000406	1.98e-01	-2.28e-01	0.211000	0.830000	0.99800	0.279000	2.11e-01	2.49e-01
Condensation of Prometaphase Chromosomes	10	1.15e-01	3.88e-01	0.6780	-5.19e-01	-0.191000	3.07e-01	-1.31e-01	-0.206000	0.004490	0.29600	0.092900	4.74e-01	2.60e-01
Transcription-Coupled Nucleotide Excision Repair (TC-NER)	68	1.16e-01	3.88e-01	0.2270	-3.22e-02	-0.162000	2.56e-02	1.29e-01	0.082600	0.647000	0.02130	0.715000	6.58e-02	2.40e-01
RNA Polymerase III Transcription Initiation From Type 1 Promoter	24	1.16e-01	3.88e-01	0.4050	-2.20e-01	-0.164000	2.62e-01	-1.62e-03	-0.142000	0.062400	0.16400	0.026500	9.89e-01	2.28e-01
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	81	1.17e-01	3.88e-01	0.1680	-7.20e-02	-0.000762	8.20e-02	1.20e-01	0.040900	0.264000	0.99100	0.203000	6.14e-02	5.26e-01
Amplification of signal from the kinetochores	81	1.17e-01	3.88e-01	0.1680	-7.20e-02	-0.000762	8.20e-02	1.20e-01	0.040900	0.264000	0.99100	0.203000	6.14e-02	5.26e-01
Telomere Maintenance	53	1.17e-01	3.89e-01	0.2970	-1.88e-01	-0.065100	1.59e-01	-5.18e-02	-0.144000	0.018300	0.41300	0.045800	5.15e-01	6.96e-02
Glycogen synthesis	11	1.19e-01	3.91e-01	0.5220	-2.26e-01	-0.156000	-1.34e-01	2.51e-01	0.341000	0.195000	0.37100	0.443000	1.49e-01	4.99e-02
NOD1/2 Signaling Pathway	22	1.19e-01	3.91e-01	0.4290	-3.16e-01	-0.156000	2.14e-01	-1.17e-01	-0.002380	0.010300	0.20400	0.083100	3.43e-01	9.85e-01
Membrane Trafficking	419	1.19e-01	3.91e-01	0.0826	-5.99e-02	-0.036300	2.21e-03	1.73e-02	0.040000	0.037600	0.20800	0.939000	5.50e-01	1.65e-01
Branched-chain amino acid catabolism	19	1.19e-01	3.91e-01	0.4750	6.32e-02	-0.037500	-2.07e-01	3.60e-01	0.219000	0.633000	0.77800	0.118000	6.67e-03	9.93e-02
Aberrant regulation of mitotic exit in cancer due to RB1 defects	15	1.20e-01	3.91e-01	0.4490	3.65e-01	-0.092400	-1.12e-01	2.07e-01	0.066300	0.014500	0.53600	0.453000	1.66e-01	6.57e-01
MAPK6/MAPK4 signaling	64	1.20e-01	3.91e-01	0.2170	-7.15e-02	-0.091000	1.03e-01	1.12e-01	0.101000	0.324000	0.20900	0.155000	1.20e-01	1.62e-01
Leishmania infection	107	1.21e-01	3.91e-01	0.1750	-7.52e-02	-0.022000	-4.13e-02	-1.03e-01	-0.110000	0.180000	0.69500	0.462000	6.74e-02	4.95e-02
Triglyceride catabolism	11	1.21e-01	3.91e-01	0.5130	1.08e-01	0.354000	-2.58e-01	-1.26e-01	-0.211000	0.536000	0.04220	0.139000	4.70e-01	2.26e-01
Glutamate Neurotransmitter Release Cycle	11	1.21e-01	3.92e-01	0.5630	1.14e-01	-0.071300	-4.97e-01	9.07e-02	0.210000	0.512000	0.68200	0.004340	6.03e-01	2.28e-01
Regulation of PTEN gene transcription	43	1.23e-01	3.93e-01	0.3340	-1.22e-01	-0.054800	1.67e-01	-2.24e-01	-0.126000	0.167000	0.53500	0.059200	1.12e-02	1.54e-01
Peroxisomal lipid metabolism	20	1.23e-01	3.93e-01	0.3710	-2.62e-01	0.152000	4.64e-02	-1.95e-01	-0.075200	0.043000	0.24000	0.720000	1.31e-01	5.61e-01
Axon guidance	283	1.24e-01	3.93e-01	0.0963	2.87e-02	-0.069900	2.33e-02	3.34e-02	0.043800	0.410000	0.04480	0.504000	3.37e-01	2.08e-01
PPARA activates gene expression	81	1.24e-01	3.93e-01	0.2080	5.44e-02	0.048400	2.90e-02	1.46e-01	0.126000	0.399000	0.45300	0.653000	2.37e-02	5.11e-02
Estrogen-dependent gene expression	64	1.24e-01	3.93e-01	0.1720	-2.05e-02	0.058500	1.36e-01	1.18e-02	0.084400	0.777000	0.41900	0.060800	8.70e-01	2.44e-01
Cytoprotection by HMOX1	90	1.24e-01	3.93e-01	0.1950	7.34e-04	0.012900	1.20e-02	1.31e-01	0.143000	0.990000	0.83300	0.845000	3.24e-02	1.94e-02
L1CAM interactions	39	1.24e-01	3.93e-01	0.2370	-9.93e-03	-0.040900	-8.30e-02	-8.21e-02	-0.202000	0.915000	0.65900	0.370000	3.75e-01	2.88e-02
GPCR ligand binding	71	1.24e-01	3.93e-01	0.1930	1.11e-01	0.040000	-1.01e-01	-8.82e-02	-0.074200	0.108000	0.56100	0.142000	2.00e-01	2.81e-01
Respiratory electron transport	71	1.25e-01	3.93e-01	0.2060	-1.05e-01	-0.090100	1.36e-01	2.86e-02	0.062800	0.127000	0.19000	0.047200	6.78e-01	3.61e-01
Purine catabolism	10	1.25e-01	3.93e-01	0.7700	-3.86e-01	-0.020800	3.89e-01	-3.98e-01	-0.367000	0.034700	0.91000	0.033200	2.95e-02	4.48e-02
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	78	1.26e-01	3.93e-01	0.1820	-1.44e-01	-0.076100	2.88e-02	7.32e-02	0.024400	0.028500	0.24600	0.661000	2.65e-01	7.10e-01
HCMV Late Events	47	1.26e-01	3.93e-01	0.2190	-1.09e-01	0.032400	1.43e-01	8.97e-02	0.080000	0.196000	0.70100	0.090600	2.88e-01	3.43e-01
Cytosolic sensors of pathogen-associated DNA	48	1.26e-01	3.93e-01	0.2530	-2.34e-02	-0.056900	-2.43e-02	2.22e-01	0.102000	0.780000	0.49600	0.771000	7.85e-03	2.22e-01
Host Interactions of HIV factors	103	1.26e-01	3.93e-01	0.1620	-7.41e-02	-0.046500	9.98e-02	8.14e-02	0.045900	0.195000	0.41600	0.080900	1.55e-01	4.22e-01
Extension of Telomeres	41	1.27e-01	3.93e-01	0.3260	-2.10e-01	-0.083800	1.91e-01	-3.64e-02	-0.132000	0.020200	0.35400	0.034800	6.87e-01	1.43e-01
Signaling by ERBB4	28	1.27e-01	3.93e-01	0.3500	9.49e-02	0.093600	-2.51e-01	1.92e-01	0.070500	0.385000	0.39200	0.021800	7.92e-02	5.19e-01
RNA Polymerase III Transcription Initiation From Type 2 Promoter	23	1.27e-01	3.93e-01	0.3920	-2.04e-01	-0.181000	2.43e-01	1.95e-02	-0.141000	0.090200	0.13200	0.043700	8.71e-01	2.42e-01
Post-translational protein phosphorylation	33	1.28e-01	3.93e-01	0.3350	-1.73e-01	-0.017300	-2.54e-02	-1.87e-01	-0.215000	0.085800	0.86400	0.801000	6.35e-02	3.25e-02
RAS processing	13	1.29e-01	3.94e-01	0.5130	9.34e-02	0.254000	5.09e-03	-3.73e-01	-0.225000	0.560000	0.11300	0.975000	2.00e-02	1.60e-01
Synthesis of IP3 and IP4 in the cytosol	16	1.29e-01	3.94e-01	0.3540	1.17e-01	0.045200	-6.81e-02	-3.20e-01	-0.051100	0.419000	0.75400	0.637000	2.68e-02	7.24e-01
FOXO-mediated transcription of cell death genes	14	1.29e-01	3.94e-01	0.3550	1.40e-01	-0.268000	1.80e-01	3.97e-02	0.032300	0.366000	0.08310	0.245000	7.97e-01	8.34e-01
Resolution of D-loop Structures through Holliday Junction Intermediates	23	1.29e-01	3.94e-01	0.2850	-2.30e-01	-0.037500	4.14e-02	1.59e-01	-0.000963	0.056600	0.75600	0.732000	1.87e-01	9.94e-01
Diseases of carbohydrate metabolism	22	1.31e-01	3.97e-01	0.3580	1.35e-01	-0.152000	-2.92e-01	1.64e-02	0.036200	0.272000	0.21600	0.017900	8.94e-01	7.69e-01
Peptide ligand-binding receptors	19	1.31e-01	3.97e-01	0.3120	9.24e-02	-0.169000	-1.68e-01	-6.10e-02	-0.169000	0.486000	0.20400	0.204000	6.45e-01	2.03e-01
TNFR2 non-canonical NF-kB pathway	65	1.32e-01	3.98e-01	0.2010	-2.38e-02	-0.060900	1.02e-01	9.21e-02	0.131000	0.741000	0.39600	0.156000	2.00e-01	6.89e-02
Degradation of GLI1 by the proteasome	50	1.34e-01	4.03e-01	0.2630	-4.82e-02	-0.132000	3.84e-02	1.39e-01	0.169000	0.556000	0.10600	0.639000	8.89e-02	3.87e-02
Metabolism of fat-soluble vitamins	13	1.34e-01	4.03e-01	0.4040	7.97e-02	-0.237000	-3.00e-01	6.55e-02	-0.078900	0.619000	0.13900	0.060900	6.83e-01	6.23e-01
PKMTs methylate histone lysines	24	1.36e-01	4.06e-01	0.4100	6.14e-02	-0.175000	1.28e-03	2.64e-01	0.253000	0.603000	0.13900	0.991000	2.53e-02	3.20e-02
Opioid Signalling	52	1.36e-01	4.06e-01	0.2540	-3.88e-04	0.074200	-2.76e-02	-2.06e-01	-0.125000	0.996000	0.35500	0.731000	1.04e-02	1.18e-01
LDL clearance	12	1.36e-01	4.06e-01	0.5300	-1.80e-01	-0.367000	-1.60e-01	1.97e-01	0.223000	0.279000	0.02800	0.338000	2.37e-01	1.82e-01
Regulation of TP53 Expression and Degradation	34	1.38e-01	4.10e-01	0.2780	-1.19e-01	-0.141000	3.39e-02	4.56e-02	0.199000	0.230000	0.15400	0.732000	6.46e-01	4.47e-02
Basigin interactions	14	1.39e-01	4.11e-01	0.3800	1.42e-01	-0.039400	1.84e-01	-2.66e-01	-0.133000	0.359000	0.79900	0.233000	8.46e-02	3.88e-01
Chromosome Maintenance	71	1.40e-01	4.14e-01	0.2270	-1.50e-01	-0.094300	9.29e-02	-1.42e-02	-0.106000	0.029100	0.17000	0.177000	8.36e-01	1.22e-01
SUMOylation of chromatin organization proteins	47	1.41e-01	4.14e-01	0.1820	-2.31e-03	0.137000	2.80e-02	-7.35e-02	0.091100	0.978000	0.10400	0.740000	3.84e-01	2.80e-01
Complex I biogenesis	38	1.41e-01	4.14e-01	0.2680	-7.30e-02	-0.160000	1.82e-01	6.06e-02	0.064200	0.436000	0.08920	0.052000	5.18e-01	4.94e-01
Late endosomal microautophagy	21	1.42e-01	4.14e-01	0.4230	-5.12e-03	-0.065500	-5.43e-02	2.43e-01	0.336000	0.968000	0.60300	0.667000	5.42e-02	7.79e-03
ROS and RNS production in phagocytes	22	1.42e-01	4.14e-01	0.4350	2.06e-01	0.194000	-2.20e-01	2.27e-01	0.095100	0.094900	0.11500	0.074200	6.59e-02	4.41e-01
Vesicle-mediated transport	426	1.42e-01	4.14e-01	0.0792	-5.99e-02	-0.034800	2.14e-03	1.41e-02	0.035800	0.036200	0.22400	0.940000	6.22e-01	2.11e-01
SUMOylation of DNA replication proteins	41	1.42e-01	4.14e-01	0.2410	-4.01e-02	0.039900	9.53e-02	1.75e-01	0.124000	0.657000	0.65900	0.292000	5.31e-02	1.70e-01
Metabolism of polyamines	46	1.44e-01	4.16e-01	0.2260	-1.35e-02	-0.074200	1.60e-01	1.18e-01	0.076300	0.874000	0.38400	0.061200	1.68e-01	3.72e-01
Transport of the SLBP Dependant Mature mRNA	31	1.44e-01	4.16e-01	0.2650	-9.25e-02	0.042200	1.36e-01	1.56e-01	0.131000	0.373000	0.68500	0.191000	1.33e-01	2.08e-01
ER-Phagosome pathway	66	1.44e-01	4.16e-01	0.2170	-1.02e-01	-0.125000	7.62e-02	9.25e-02	0.082100	0.154000	0.07880	0.285000	1.94e-01	2.49e-01
Regulation of IFNA signaling	12	1.45e-01	4.17e-01	0.5120	1.26e-01	0.104000	2.31e-01	-2.92e-01	-0.311000	0.450000	0.53200	0.166000	7.98e-02	6.22e-02
Aberrant regulation of mitotic cell cycle due to RB1 defects	29	1.45e-01	4.18e-01	0.2790	2.69e-01	-0.004430	-6.92e-02	2.09e-02	-0.023600	0.012300	0.96700	0.519000	8.46e-01	8.26e-01
HSP90 chaperone cycle for steroid hormone receptors (SHR)	32	1.49e-01	4.25e-01	0.2960	-6.51e-02	-0.026700	2.71e-01	7.54e-03	-0.095300	0.524000	0.79400	0.007950	9.41e-01	3.51e-01
Metabolism of cofactors	17	1.49e-01	4.25e-01	0.3080	1.95e-01	0.088500	1.79e-01	-1.01e-02	0.129000	0.163000	0.52800	0.200000	9.42e-01	3.59e-01
TP53 Regulates Transcription of Cell Death Genes	29	1.50e-01	4.27e-01	0.2720	1.34e-01	-0.198000	-1.15e-01	-2.38e-02	0.055500	0.213000	0.06490	0.285000	8.25e-01	6.05e-01
Cellular response to heat stress	75	1.51e-01	4.29e-01	0.1730	-1.07e-01	-0.019700	6.38e-02	1.00e-01	0.061100	0.109000	0.76900	0.340000	1.34e-01	3.61e-01
Endosomal Sorting Complex Required For Transport (ESCRT)	24	1.53e-01	4.33e-01	0.3470	1.00e-02	0.000728	5.87e-02	1.98e-01	0.279000	0.932000	0.99500	0.619000	9.40e-02	1.82e-02
p75NTR signals via NF-kB	11	1.55e-01	4.38e-01	0.4470	-2.92e-01	-0.110000	-5.23e-02	2.50e-01	0.194000	0.093600	0.52800	0.764000	1.52e-01	2.65e-01
Dual incision in TC-NER	55	1.55e-01	4.38e-01	0.2290	-4.96e-02	-0.181000	7.06e-02	9.90e-02	0.050800	0.525000	0.02080	0.366000	2.05e-01	5.15e-01
HCMV Infection	67	1.55e-01	4.38e-01	0.2040	-1.02e-01	0.045100	1.70e-01	-3.35e-04	-0.014700	0.150000	0.52400	0.016100	9.96e-01	8.36e-01
Ion channel transport	74	1.57e-01	4.41e-01	0.2470	1.16e-01	0.103000	-1.47e-01	8.19e-02	0.092100	0.085900	0.12500	0.029000	2.24e-01	1.71e-01
Costimulation by the CD28 family	44	1.60e-01	4.47e-01	0.2690	-9.40e-03	0.096700	1.13e-01	-2.05e-01	-0.089400	0.914000	0.26700	0.196000	1.86e-02	3.05e-01
Mitotic Spindle Checkpoint	93	1.60e-01	4.47e-01	0.1520	-1.97e-02	-0.008990	5.14e-02	1.36e-01	0.038900	0.744000	0.88100	0.393000	2.42e-02	5.18e-01
Regulated Necrosis	41	1.62e-01	4.50e-01	0.2780	-4.86e-02	-0.175000	6.06e-02	1.50e-01	0.133000	0.591000	0.05270	0.503000	9.67e-02	1.40e-01
Transport to the Golgi and subsequent modification	124	1.62e-01	4.50e-01	0.1450	-1.32e-01	-0.056300	1.16e-02	4.30e-03	-0.017300	0.011700	0.28000	0.823000	9.34e-01	7.40e-01
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	37	1.62e-01	4.50e-01	0.2850	-2.10e-01	-0.182000	3.97e-02	4.39e-02	0.007360	0.027100	0.05530	0.676000	6.44e-01	9.38e-01
Rev-mediated nuclear export of HIV RNA	31	1.63e-01	4.51e-01	0.2460	-8.00e-02	0.104000	9.94e-02	1.63e-01	0.083600	0.441000	0.31800	0.338000	1.16e-01	4.21e-01
Erythropoietin activates RAS	10	1.64e-01	4.53e-01	0.5830	2.82e-01	0.405000	-1.91e-01	2.38e-01	0.048200	0.123000	0.02650	0.296000	1.92e-01	7.92e-01
Non-integrin membrane-ECM interactions	12	1.68e-01	4.62e-01	0.4300	-1.71e-02	-0.273000	-3.78e-02	-3.02e-01	-0.132000	0.918000	0.10200	0.821000	7.04e-02	4.28e-01
Association of TriC/CCT with target proteins during biosynthesis	28	1.68e-01	4.62e-01	0.2880	-9.94e-02	-0.129000	1.88e-01	1.45e-01	0.002910	0.363000	0.23800	0.085700	1.83e-01	9.79e-01
Interactions of Rev with host cellular proteins	32	1.70e-01	4.63e-01	0.2370	-9.31e-02	0.107000	1.12e-01	1.38e-01	0.067500	0.363000	0.29500	0.272000	1.76e-01	5.09e-01
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism	10	1.70e-01	4.63e-01	0.5110	-1.33e-01	0.184000	-1.79e-01	-3.37e-01	-0.253000	0.467000	0.31500	0.327000	6.55e-02	1.66e-01
alpha-linolenic acid (ALA) metabolism	10	1.70e-01	4.63e-01	0.5110	-1.33e-01	0.184000	-1.79e-01	-3.37e-01	-0.253000	0.467000	0.31500	0.327000	6.55e-02	1.66e-01
PCP/CE pathway	70	1.70e-01	4.63e-01	0.2120	-4.14e-02	-0.136000	4.35e-02	1.04e-01	0.109000	0.550000	0.04880	0.530000	1.35e-01	1.15e-01
Transport of the SLBP independent Mature mRNA	30	1.70e-01	4.63e-01	0.2610	-9.49e-02	0.039900	1.22e-01	1.40e-01	0.151000	0.369000	0.70500	0.247000	1.84e-01	1.52e-01
Removal of the Flap Intermediate	12	1.71e-01	4.63e-01	0.4520	-3.65e-01	-0.118000	1.95e-01	1.37e-01	0.009270	0.028700	0.47900	0.242000	4.11e-01	9.56e-01
Regulation of PLK1 Activity at G2/M Transition	63	1.71e-01	4.63e-01	0.2030	-5.72e-02	-0.109000	1.22e-01	7.59e-02	0.073000	0.433000	0.13400	0.094400	2.98e-01	3.17e-01
SUMOylation of RNA binding proteins	40	1.72e-01	4.63e-01	0.1990	-1.32e-01	0.091200	7.88e-02	-1.57e-02	0.085300	0.148000	0.31900	0.389000	8.64e-01	3.51e-01
Gastrin-CREB signalling pathway via PKC and MAPK	11	1.73e-01	4.65e-01	0.4250	1.17e-02	0.232000	-3.19e-01	-1.54e-01	0.032500	0.947000	0.18300	0.067000	3.75e-01	8.52e-01
Metabolism of carbohydrates	172	1.73e-01	4.65e-01	0.1090	-3.91e-03	-0.020500	-6.99e-02	-5.14e-02	-0.061900	0.930000	0.64400	0.116000	2.47e-01	1.63e-01
Semaphorin interactions	36	1.74e-01	4.65e-01	0.2270	3.09e-02	-0.112000	-3.68e-02	-1.84e-01	-0.054800	0.748000	0.24500	0.703000	5.68e-02	5.70e-01
Anchoring of the basal body to the plasma membrane	70	1.74e-01	4.65e-01	0.1990	-8.60e-02	-0.107000	1.30e-01	4.27e-02	0.045300	0.215000	0.12100	0.060100	5.37e-01	5.13e-01
Nuclear Pore Complex (NPC) Disassembly	32	1.75e-01	4.65e-01	0.2570	-1.41e-01	0.009380	1.70e-01	9.45e-02	0.090300	0.168000	0.92700	0.095700	3.56e-01	3.77e-01
Regulation of HMOX1 expression and activity	54	1.76e-01	4.68e-01	0.2390	1.06e-02	-0.111000	4.45e-02	1.28e-01	0.161000	0.893000	0.15800	0.572000	1.05e-01	4.04e-02
RNA Polymerase III Transcription Initiation From Type 3 Promoter	25	1.76e-01	4.68e-01	0.3080	-2.22e-01	-0.160000	3.95e-02	3.06e-02	-0.134000	0.055200	0.16700	0.732000	7.91e-01	2.47e-01
Antigen processing-Cross presentation	71	1.78e-01	4.70e-01	0.2040	-6.00e-02	-0.124000	5.97e-02	1.04e-01	0.091300	0.383000	0.07180	0.385000	1.31e-01	1.84e-01
Collagen formation	19	1.78e-01	4.70e-01	0.2980	2.19e-01	-0.042000	-1.20e-01	-1.57e-01	0.009990	0.099300	0.75200	0.364000	2.37e-01	9.40e-01
Fatty acyl-CoA biosynthesis	22	1.78e-01	4.70e-01	0.3490	2.03e-01	0.226000	7.92e-02	-7.75e-02	-0.132000	0.098700	0.06650	0.520000	5.29e-01	2.86e-01
Bile acid and bile salt metabolism	14	1.79e-01	4.70e-01	0.4280	9.33e-02	0.371000	-1.80e-01	1.08e-02	0.066000	0.546000	0.01610	0.244000	9.44e-01	6.69e-01
Gene Silencing by RNA	54	1.79e-01	4.70e-01	0.1940	-7.64e-02	0.054900	1.58e-01	4.25e-02	0.044100	0.332000	0.48600	0.044500	5.90e-01	5.75e-01
p75 NTR receptor-mediated signalling	54	1.79e-01	4.70e-01	0.1580	-1.15e-01	0.068700	-3.16e-02	6.88e-02	0.035000	0.145000	0.38400	0.688000	3.83e-01	6.57e-01
Class A/1 (Rhodopsin-like receptors)	44	1.80e-01	4.70e-01	0.2150	7.45e-02	-0.008540	-9.17e-02	-9.63e-02	-0.151000	0.393000	0.92200	0.293000	2.70e-01	8.29e-02
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer’s disease models	20	1.81e-01	4.70e-01	0.3160	2.68e-01	-0.032100	-1.41e-01	-5.73e-03	-0.082000	0.037800	0.80400	0.275000	9.65e-01	5.26e-01
Neurodegenerative Diseases	20	1.81e-01	4.70e-01	0.3160	2.68e-01	-0.032100	-1.41e-01	-5.73e-03	-0.082000	0.037800	0.80400	0.275000	9.65e-01	5.26e-01
KSRP (KHSRP) binds and destabilizes mRNA	14	1.81e-01	4.70e-01	0.5620	-3.84e-01	-0.193000	2.75e-01	-1.57e-01	-0.174000	0.012800	0.21100	0.074500	3.09e-01	2.61e-01
RAF-independent MAPK1/3 activation	19	1.82e-01	4.71e-01	0.3180	1.53e-01	0.086700	-3.83e-02	-4.12e-02	-0.259000	0.248000	0.51300	0.772000	7.56e-01	5.07e-02
DNA Damage/Telomere Stress Induced Senescence	24	1.83e-01	4.72e-01	0.3090	-3.08e-02	-0.064300	2.03e-01	-1.11e-02	-0.221000	0.794000	0.58600	0.085800	9.25e-01	6.07e-02
Interferon gamma signaling	53	1.84e-01	4.72e-01	0.2580	-4.64e-03	0.001590	6.45e-02	-1.92e-01	-0.159000	0.953000	0.98400	0.417000	1.56e-02	4.49e-02
RHO GTPases Activate Formins	100	1.84e-01	4.72e-01	0.1460	-8.27e-02	-0.017600	8.68e-02	7.82e-02	0.025000	0.154000	0.76200	0.135000	1.78e-01	6.67e-01
FOXO-mediated transcription	45	1.85e-01	4.73e-01	0.1690	4.36e-02	-0.070600	1.19e-01	-6.04e-02	0.061000	0.613000	0.41300	0.168000	4.84e-01	4.80e-01
MAPK family signaling cascades	176	1.85e-01	4.74e-01	0.1370	-3.09e-03	0.054800	7.70e-02	-3.49e-02	-0.093100	0.944000	0.21200	0.079400	4.26e-01	3.40e-02
AURKA Activation by TPX2	51	1.90e-01	4.82e-01	0.2150	-3.91e-02	-0.143000	1.41e-01	5.86e-02	0.031700	0.630000	0.07830	0.082900	4.70e-01	6.96e-01
Mitochondrial iron-sulfur cluster biogenesis	10	1.90e-01	4.82e-01	0.4860	-9.58e-02	-0.194000	2.37e-01	1.99e-01	0.305000	0.600000	0.28700	0.195000	2.76e-01	9.45e-02
Activation of BH3-only proteins	25	1.90e-01	4.82e-01	0.2470	1.12e-01	0.009080	1.16e-02	-2.18e-01	-0.026000	0.332000	0.93700	0.920000	5.91e-02	8.22e-01
Downregulation of SMAD2/3:SMAD4 transcriptional activity	21	1.91e-01	4.84e-01	0.2380	-6.78e-02	0.093700	-1.52e-01	8.60e-02	-0.113000	0.591000	0.45800	0.229000	4.95e-01	3.69e-01
Resolution of D-Loop Structures	24	1.92e-01	4.84e-01	0.2540	-2.17e-01	-0.019600	1.12e-02	1.30e-01	0.007870	0.066400	0.86800	0.924000	2.69e-01	9.47e-01
Translesion synthesis by POLI	15	1.92e-01	4.84e-01	0.4250	-1.17e-01	-0.082000	3.35e-02	2.76e-01	0.288000	0.435000	0.58200	0.822000	6.45e-02	5.34e-02
Recognition of DNA damage by PCNA-containing replication complex	25	1.93e-01	4.86e-01	0.2980	-2.06e-01	-0.130000	3.33e-02	1.55e-01	0.064800	0.075100	0.26200	0.773000	1.79e-01	5.75e-01
RND1 GTPase cycle	29	1.94e-01	4.88e-01	0.2960	-6.91e-02	-0.260000	1.22e-01	-1.40e-04	-0.022200	0.520000	0.01560	0.254000	9.99e-01	8.36e-01
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	10	1.97e-01	4.92e-01	0.4730	-1.16e-01	-0.170000	5.71e-02	-4.15e-01	-0.078500	0.527000	0.35300	0.755000	2.32e-02	6.67e-01
Termination of translesion DNA synthesis	28	1.97e-01	4.92e-01	0.3320	-1.04e-01	-0.243000	5.72e-03	1.33e-01	0.151000	0.343000	0.02600	0.958000	2.22e-01	1.67e-01
Retrograde transport at the Trans-Golgi-Network	42	1.97e-01	4.92e-01	0.2280	-1.34e-01	-0.051200	-9.15e-03	1.18e-01	0.133000	0.135000	0.56700	0.918000	1.88e-01	1.36e-01
BBSome-mediated cargo-targeting to cilium	18	1.98e-01	4.92e-01	0.4180	-1.24e-01	-0.273000	-6.73e-02	1.97e-01	0.202000	0.362000	0.04470	0.621000	1.47e-01	1.38e-01
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon	13	1.98e-01	4.92e-01	0.4100	-1.01e-01	0.086400	-1.36e-01	2.86e-01	0.224000	0.529000	0.59000	0.397000	7.47e-02	1.62e-01
Metabolism of water-soluble vitamins and cofactors	76	2.01e-01	4.98e-01	0.1940	-4.27e-02	-0.044500	8.24e-02	-5.11e-02	-0.156000	0.521000	0.50400	0.215000	4.42e-01	1.91e-02
Intra-Golgi and retrograde Golgi-to-ER traffic	151	2.01e-01	4.98e-01	0.1210	-7.13e-02	-0.023700	7.67e-02	2.38e-02	0.050700	0.132000	0.61600	0.105000	6.16e-01	2.85e-01
Detoxification of Reactive Oxygen Species	22	2.02e-01	4.98e-01	0.3810	2.63e-01	0.239000	-3.55e-02	1.25e-01	0.044200	0.032600	0.05260	0.774000	3.10e-01	7.20e-01
RNA Polymerase III Abortive And Retractive Initiation	36	2.05e-01	5.03e-01	0.2760	-1.75e-01	-0.120000	1.24e-01	2.05e-02	-0.123000	0.070000	0.21200	0.197000	8.32e-01	2.01e-01
RNA Polymerase III Transcription	36	2.05e-01	5.03e-01	0.2760	-1.75e-01	-0.120000	1.24e-01	2.05e-02	-0.123000	0.070000	0.21200	0.197000	8.32e-01	2.01e-01
RND3 GTPase cycle	28	2.06e-01	5.03e-01	0.3130	-1.27e-01	-0.270000	4.54e-02	-8.42e-02	0.007120	0.245000	0.01350	0.678000	4.41e-01	9.48e-01
rRNA modification in the nucleus and cytosol	42	2.06e-01	5.03e-01	0.2650	8.00e-03	-0.083300	4.98e-02	1.92e-01	0.154000	0.929000	0.35100	0.577000	3.19e-02	8.36e-02
RNA Polymerase II Pre-transcription Events	60	2.07e-01	5.03e-01	0.2000	-2.56e-02	-0.102000	9.50e-02	8.76e-02	0.110000	0.732000	0.17300	0.204000	2.41e-01	1.41e-01
Negative regulation of FGFR1 signaling	17	2.08e-01	5.03e-01	0.3140	-1.69e-01	-0.114000	-2.18e-01	9.09e-02	0.034200	0.228000	0.41600	0.120000	5.17e-01	8.07e-01
Negative regulation of FGFR2 signaling	17	2.08e-01	5.03e-01	0.3140	-1.69e-01	-0.114000	-2.18e-01	9.09e-02	0.034200	0.228000	0.41600	0.120000	5.17e-01	8.07e-01
Negative regulation of FGFR3 signaling	17	2.08e-01	5.03e-01	0.3140	-1.69e-01	-0.114000	-2.18e-01	9.09e-02	0.034200	0.228000	0.41600	0.120000	5.17e-01	8.07e-01
Negative regulation of FGFR4 signaling	17	2.08e-01	5.03e-01	0.3140	-1.69e-01	-0.114000	-2.18e-01	9.09e-02	0.034200	0.228000	0.41600	0.120000	5.17e-01	8.07e-01
Myogenesis	13	2.09e-01	5.05e-01	0.4930	-4.23e-01	-0.146000	1.74e-01	-7.40e-02	-0.084600	0.008350	0.36100	0.276000	6.44e-01	5.98e-01
Ephrin signaling	12	2.10e-01	5.06e-01	0.4130	9.02e-02	-0.080400	-1.31e-01	-2.75e-01	-0.251000	0.589000	0.63000	0.432000	9.86e-02	1.32e-01
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding	18	2.11e-01	5.06e-01	0.3590	-5.89e-03	-0.114000	4.18e-02	3.19e-01	0.112000	0.966000	0.40400	0.759000	1.94e-02	4.12e-01
Translesion synthesis by REV1	14	2.11e-01	5.06e-01	0.4210	-1.69e-01	-0.118000	4.93e-02	2.63e-01	0.252000	0.274000	0.44300	0.750000	8.80e-02	1.03e-01
DCC mediated attractive signaling	11	2.13e-01	5.09e-01	0.4950	-1.30e-01	-0.098100	1.71e-01	-4.16e-01	-0.129000	0.456000	0.57300	0.326000	1.70e-02	4.58e-01
Synthesis of bile acids and bile salts	13	2.13e-01	5.09e-01	0.4090	5.06e-02	0.374000	-1.44e-01	-5.26e-02	0.035300	0.752000	0.01950	0.370000	7.43e-01	8.26e-01
Nuclear Envelope Breakdown	45	2.13e-01	5.10e-01	0.2180	-1.03e-01	-0.038000	1.62e-01	9.45e-02	0.014200	0.230000	0.66000	0.060000	2.73e-01	8.69e-01
Transcriptional regulation of white adipocyte differentiation	55	2.15e-01	5.11e-01	0.2420	5.91e-02	0.045800	-6.94e-03	1.49e-01	0.175000	0.449000	0.55800	0.929000	5.68e-02	2.46e-02
Cleavage of the damaged purine	10	2.17e-01	5.14e-01	0.4960	4.67e-04	-0.102000	4.45e-02	-2.47e-01	-0.416000	0.998000	0.57700	0.808000	1.77e-01	2.27e-02
Depurination	10	2.17e-01	5.14e-01	0.4960	4.67e-04	-0.102000	4.45e-02	-2.47e-01	-0.416000	0.998000	0.57700	0.808000	1.77e-01	2.27e-02
Recognition and association of DNA glycosylase with site containing an affected purine	10	2.17e-01	5.14e-01	0.4960	4.67e-04	-0.102000	4.45e-02	-2.47e-01	-0.416000	0.998000	0.57700	0.808000	1.77e-01	2.27e-02
mRNA Splicing - Minor Pathway	42	2.18e-01	5.14e-01	0.2140	-4.13e-02	0.055000	9.05e-02	1.47e-01	0.106000	0.644000	0.53800	0.311000	9.93e-02	2.34e-01
Postmitotic nuclear pore complex (NPC) reformation	25	2.18e-01	5.14e-01	0.2870	-2.40e-02	0.070500	1.06e-01	1.79e-01	0.183000	0.836000	0.54200	0.359000	1.22e-01	1.14e-01
Sialic acid metabolism	22	2.19e-01	5.15e-01	0.2880	1.83e-02	-0.177000	6.02e-02	2.18e-01	0.013000	0.882000	0.15100	0.625000	7.64e-02	9.16e-01
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	22	2.25e-01	5.27e-01	0.3690	6.15e-02	0.007600	1.98e-02	2.95e-01	0.212000	0.618000	0.95100	0.873000	1.65e-02	8.57e-02
RNA Polymerase II Transcription	856	2.26e-01	5.27e-01	0.0565	-3.19e-02	-0.031700	1.56e-02	1.25e-02	0.027800	0.123000	0.12500	0.450000	5.45e-01	1.78e-01
TCF dependent signaling in response to WNT	117	2.26e-01	5.27e-01	0.1510	4.95e-02	-0.045400	2.28e-02	7.64e-02	0.109000	0.356000	0.39800	0.671000	1.55e-01	4.19e-02
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	12	2.26e-01	5.27e-01	0.3340	-2.15e-01	0.089700	1.18e-01	1.69e-01	-0.124000	0.198000	0.59100	0.480000	3.12e-01	4.58e-01
RMTs methylate histone arginines	23	2.27e-01	5.27e-01	0.3500	1.55e-01	-0.018500	4.47e-02	1.96e-01	0.240000	0.198000	0.87800	0.711000	1.03e-01	4.65e-02
Hyaluronan metabolism	10	2.27e-01	5.27e-01	0.3970	-2.35e-01	0.045100	-2.07e-01	-2.36e-01	-0.036900	0.198000	0.80500	0.256000	1.96e-01	8.40e-01
Interleukin-2 family signaling	28	2.28e-01	5.28e-01	0.2920	4.82e-02	0.113000	2.19e-01	-5.64e-02	-0.138000	0.659000	0.30200	0.044800	6.06e-01	2.05e-01
TNF signaling	35	2.28e-01	5.28e-01	0.2280	-8.80e-02	0.032100	-9.09e-03	1.77e-01	0.110000	0.368000	0.74300	0.926000	7.06e-02	2.61e-01
Nuclear signaling by ERBB4	14	2.29e-01	5.29e-01	0.3380	7.27e-02	0.038700	-2.48e-01	2.04e-01	-0.064700	0.638000	0.80200	0.108000	1.86e-01	6.75e-01
Diseases of programmed cell death	36	2.31e-01	5.33e-01	0.1820	1.44e-01	-0.032900	1.39e-02	-1.06e-01	0.001380	0.136000	0.73300	0.886000	2.70e-01	9.89e-01
Ub-specific processing proteases	130	2.32e-01	5.33e-01	0.1400	5.03e-02	-0.002640	3.76e-02	8.86e-02	0.088800	0.324000	0.95900	0.461000	8.23e-02	8.14e-02
Sphingolipid de novo biosynthesis	18	2.34e-01	5.35e-01	0.3040	-2.82e-02	0.207000	1.64e-01	1.40e-01	-0.053300	0.836000	0.12900	0.230000	3.04e-01	6.96e-01
G alpha (q) signalling events	70	2.34e-01	5.35e-01	0.1950	1.86e-02	0.133000	-2.93e-02	-1.17e-01	-0.073800	0.789000	0.05410	0.672000	9.25e-02	2.87e-01
Signaling by PDGF	24	2.37e-01	5.43e-01	0.3030	8.78e-02	0.052000	-6.45e-02	-1.52e-01	-0.232000	0.457000	0.66000	0.585000	1.97e-01	4.94e-02
Pyruvate metabolism	19	2.39e-01	5.45e-01	0.3160	2.23e-01	-0.052200	-1.99e-01	-8.49e-02	-0.010900	0.092500	0.69400	0.133000	5.22e-01	9.34e-01
Nucleotide Excision Repair	98	2.42e-01	5.49e-01	0.1640	-1.58e-02	-0.081600	1.29e-03	1.26e-01	0.065700	0.788000	0.16400	0.982000	3.20e-02	2.62e-01
COPI-mediated anterograde transport	67	2.42e-01	5.49e-01	0.1900	-1.50e-01	-0.074800	7.49e-02	3.96e-02	0.028900	0.034300	0.29100	0.290000	5.76e-01	6.83e-01
DAP12 signaling	19	2.42e-01	5.49e-01	0.3350	-1.66e-02	0.188000	1.64e-01	-2.20e-01	-0.040300	0.901000	0.15600	0.216000	9.77e-02	7.61e-01
Oncogenic MAPK signaling	54	2.42e-01	5.49e-01	0.2090	7.54e-02	0.148000	-1.70e-02	-2.25e-02	-0.124000	0.339000	0.06060	0.829000	7.75e-01	1.16e-01
Diseases of mitotic cell cycle	30	2.44e-01	5.51e-01	0.2440	2.33e-01	-0.006030	-5.48e-02	2.92e-02	-0.035800	0.027500	0.95400	0.604000	7.82e-01	7.34e-01
Nuclear import of Rev protein	29	2.44e-01	5.51e-01	0.2380	-1.27e-01	0.059300	1.33e-01	1.08e-01	0.087600	0.235000	0.58100	0.216000	3.15e-01	4.14e-01
Regulation of TP53 Activity	130	2.45e-01	5.51e-01	0.1420	-6.57e-02	-0.095300	7.22e-02	1.40e-02	0.035400	0.198000	0.06160	0.157000	7.83e-01	4.87e-01
RHO GTPases Activate WASPs and WAVEs	28	2.45e-01	5.51e-01	0.2970	-5.00e-02	-0.141000	9.01e-02	-1.09e-01	-0.214000	0.647000	0.19800	0.410000	3.21e-01	5.00e-02
Potassium Channels	23	2.46e-01	5.53e-01	0.3220	1.80e-01	0.126000	-1.46e-01	-1.38e-02	0.185000	0.136000	0.29600	0.227000	9.09e-01	1.25e-01
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	15	2.47e-01	5.53e-01	0.3550	8.45e-02	0.125000	2.12e-01	-2.30e-01	-0.071300	0.571000	0.40100	0.156000	1.22e-01	6.33e-01
Regulation of pyruvate dehydrogenase (PDH) complex	11	2.48e-01	5.53e-01	0.4700	2.64e-01	0.052700	-3.60e-01	-7.62e-02	0.110000	0.129000	0.76200	0.038500	6.62e-01	5.27e-01
Telomere Extension By Telomerase	19	2.48e-01	5.53e-01	0.4010	-1.91e-01	-0.146000	2.31e-01	-4.80e-02	-0.218000	0.150000	0.27200	0.081800	7.18e-01	1.01e-01
DAP12 interactions	21	2.49e-01	5.53e-01	0.3340	7.25e-04	0.195000	1.15e-01	-2.34e-01	-0.073100	0.995000	0.12200	0.361000	6.34e-02	5.62e-01
RUNX2 regulates bone development	17	2.50e-01	5.55e-01	0.2980	-4.79e-02	-0.012800	-2.59e-01	-8.36e-02	-0.112000	0.732000	0.92700	0.064400	5.51e-01	4.26e-01
Formation of the beta-catenin:TCF transactivating complex	24	2.51e-01	5.56e-01	0.2640	-4.36e-02	0.176000	1.61e-01	9.52e-02	0.042300	0.712000	0.13600	0.171000	4.20e-01	7.20e-01
Elastic fibre formation	15	2.52e-01	5.56e-01	0.3560	1.60e-01	0.043600	-1.80e-01	-2.21e-01	-0.136000	0.285000	0.77000	0.228000	1.38e-01	3.63e-01
tRNA Aminoacylation	21	2.52e-01	5.56e-01	0.3100	-2.31e-01	-0.119000	1.00e-01	-8.42e-02	0.107000	0.067400	0.34500	0.427000	5.04e-01	3.95e-01
Iron uptake and transport	37	2.52e-01	5.56e-01	0.2800	4.27e-02	0.105000	-1.21e-01	1.75e-01	0.142000	0.654000	0.26900	0.204000	6.60e-02	1.34e-01
G alpha (12/13) signalling events	33	2.53e-01	5.56e-01	0.2080	-7.65e-02	0.170000	6.53e-02	-2.26e-03	0.065700	0.447000	0.09080	0.517000	9.82e-01	5.14e-01
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	20	2.54e-01	5.57e-01	0.2780	-2.54e-01	-0.059600	-3.68e-02	7.20e-02	0.052100	0.049300	0.64500	0.776000	5.78e-01	6.87e-01
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	23	2.55e-01	5.58e-01	0.3800	-3.05e-01	-0.095900	1.48e-01	-1.19e-01	-0.078300	0.011300	0.42600	0.220000	3.23e-01	5.16e-01
CLEC7A (Dectin-1) signaling	81	2.56e-01	5.60e-01	0.1610	-8.07e-02	-0.069200	1.05e-01	-1.28e-02	0.057800	0.210000	0.28300	0.104000	8.42e-01	3.70e-01
Budding and maturation of HIV virion	21	2.57e-01	5.60e-01	0.3670	3.28e-02	-0.055400	3.53e-02	2.38e-01	0.269000	0.795000	0.66100	0.780000	5.91e-02	3.29e-02
Class I peroxisomal membrane protein import	18	2.57e-01	5.60e-01	0.3360	-4.92e-02	0.009120	3.21e-01	-8.34e-02	-0.023900	0.718000	0.94700	0.018500	5.40e-01	8.61e-01
Activation of the pre-replicative complex	23	2.61e-01	5.66e-01	0.2850	3.01e-02	-0.022100	1.52e-01	2.15e-01	0.102000	0.803000	0.85500	0.206000	7.51e-02	3.96e-01
Glycogen storage diseases	10	2.61e-01	5.66e-01	0.5710	1.09e-01	-0.193000	-4.01e-01	2.18e-01	0.262000	0.551000	0.29000	0.028000	2.33e-01	1.52e-01
Translation of Replicase and Assembly of the Replication Transcription Complex	10	2.61e-01	5.66e-01	0.4630	-2.13e-02	-0.050200	1.19e-01	2.38e-01	0.375000	0.907000	0.78400	0.516000	1.93e-01	3.99e-02
Fanconi Anemia Pathway	29	2.62e-01	5.66e-01	0.2650	-6.14e-02	-0.068300	-4.86e-02	2.26e-01	0.089900	0.567000	0.52500	0.651000	3.52e-02	4.02e-01
Constitutive Signaling by Aberrant PI3K in Cancer	26	2.63e-01	5.68e-01	0.3780	-1.08e-01	0.037400	6.46e-02	-2.32e-01	-0.268000	0.340000	0.74100	0.569000	4.07e-02	1.82e-02
Clathrin-mediated endocytosis	89	2.64e-01	5.68e-01	0.1480	-1.03e-01	-0.085500	-4.35e-02	3.73e-02	0.025400	0.095300	0.16400	0.480000	5.44e-01	6.79e-01
Downstream signaling events of B Cell Receptor (BCR)	67	2.64e-01	5.68e-01	0.1690	-1.09e-02	-0.079100	1.01e-01	6.37e-02	0.089200	0.877000	0.26400	0.154000	3.68e-01	2.08e-01
CD28 dependent PI3K/Akt signaling	18	2.68e-01	5.75e-01	0.3300	-1.05e-01	0.037300	1.16e-01	-2.86e-01	-0.028700	0.439000	0.78400	0.395000	3.55e-02	8.33e-01
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	14	2.70e-01	5.77e-01	0.3620	6.70e-02	0.279000	9.52e-02	-1.99e-01	-0.001840	0.664000	0.07080	0.538000	1.98e-01	9.90e-01
Nucleobase catabolism	20	2.70e-01	5.77e-01	0.4390	-1.92e-01	0.040600	1.45e-01	-2.02e-01	-0.304000	0.138000	0.75400	0.260000	1.17e-01	1.85e-02
Pyroptosis	17	2.70e-01	5.77e-01	0.3740	4.10e-02	-0.146000	1.10e-01	2.47e-01	0.209000	0.770000	0.29600	0.431000	7.79e-02	1.36e-01
Signaling by Leptin	10	2.71e-01	5.77e-01	0.4520	3.18e-01	0.264000	3.16e-03	6.42e-02	-0.171000	0.081700	0.14900	0.986000	7.25e-01	3.50e-01
Peroxisomal protein import	45	2.72e-01	5.77e-01	0.1810	-1.01e-01	0.132000	6.89e-02	2.26e-02	0.005120	0.240000	0.12600	0.425000	7.93e-01	9.53e-01
Signaling by KIT in disease	16	2.73e-01	5.77e-01	0.3910	1.09e-01	0.326000	-9.23e-02	-1.25e-01	-0.105000	0.452000	0.02400	0.523000	3.88e-01	4.69e-01
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	16	2.73e-01	5.77e-01	0.3910	1.09e-01	0.326000	-9.23e-02	-1.25e-01	-0.105000	0.452000	0.02400	0.523000	3.88e-01	4.69e-01
Deubiquitination	188	2.75e-01	5.81e-01	0.1240	4.71e-02	0.007830	-2.52e-03	6.37e-02	0.095200	0.268000	0.85400	0.953000	1.34e-01	2.51e-02
FCERI mediated NF-kB activation	61	2.78e-01	5.86e-01	0.1880	-5.40e-02	-0.089100	8.61e-02	7.68e-02	0.105000	0.467000	0.23000	0.245000	3.00e-01	1.56e-01
SUMOylation of ubiquitinylation proteins	35	2.79e-01	5.86e-01	0.2110	-7.53e-02	0.078300	1.55e-01	5.76e-02	0.072400	0.441000	0.42400	0.112000	5.56e-01	4.59e-01
tRNA processing	82	2.79e-01	5.86e-01	0.1610	-8.70e-02	-0.053900	1.02e-01	5.09e-02	0.049600	0.174000	0.40000	0.112000	4.26e-01	4.39e-01
Condensation of Prophase Chromosomes	12	2.80e-01	5.86e-01	0.5460	-3.46e-01	-0.217000	1.38e-01	-2.38e-01	-0.235000	0.037900	0.19200	0.407000	1.53e-01	1.58e-01
Export of Viral Ribonucleoproteins from Nucleus	29	2.81e-01	5.89e-01	0.2390	-1.22e-01	0.013000	9.76e-02	1.25e-01	0.131000	0.256000	0.90400	0.363000	2.45e-01	2.23e-01
TP53 Regulates Transcription of DNA Repair Genes	45	2.82e-01	5.89e-01	0.2400	-4.70e-02	-0.157000	1.69e-02	1.40e-01	0.104000	0.586000	0.06800	0.844000	1.04e-01	2.28e-01
Ion transport by P-type ATPases	26	2.83e-01	5.90e-01	0.3080	1.57e-01	0.213000	-3.58e-02	-1.14e-01	-0.104000	0.167000	0.06050	0.752000	3.13e-01	3.58e-01
Unfolded Protein Response (UPR)	67	2.83e-01	5.90e-01	0.1740	-1.30e-01	-0.010500	1.09e-01	3.75e-02	0.002730	0.065600	0.88200	0.124000	5.96e-01	9.69e-01
Sulfur amino acid metabolism	15	2.84e-01	5.90e-01	0.4310	2.84e-02	0.126000	1.47e-02	-2.52e-01	-0.325000	0.849000	0.39900	0.921000	9.16e-02	2.96e-02
RHOB GTPase cycle	40	2.86e-01	5.90e-01	0.2020	-2.75e-02	0.064900	1.16e-01	-1.49e-01	0.003210	0.764000	0.47800	0.206000	1.03e-01	9.72e-01
Cargo trafficking to the periciliary membrane	38	2.86e-01	5.90e-01	0.2480	-7.14e-02	-0.128000	-1.32e-01	7.21e-02	0.131000	0.447000	0.17200	0.160000	4.42e-01	1.61e-01
Signaling by WNT	168	2.86e-01	5.90e-01	0.1010	3.11e-02	-0.011600	5.09e-02	4.39e-02	0.067200	0.489000	0.79600	0.257000	3.29e-01	1.35e-01
Interleukin-10 signaling	13	2.86e-01	5.90e-01	0.3470	2.69e-01	-0.160000	-1.48e-01	-2.24e-02	0.018700	0.093000	0.31900	0.355000	8.89e-01	9.07e-01
RAC2 GTPase cycle	52	2.87e-01	5.90e-01	0.1950	1.08e-01	0.080600	-2.78e-02	1.56e-02	0.137000	0.178000	0.31500	0.730000	8.46e-01	8.84e-02
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	12	2.87e-01	5.90e-01	0.3110	-1.89e-01	0.134000	7.47e-02	1.30e-01	-0.143000	0.257000	0.42300	0.654000	4.35e-01	3.90e-01
Mitochondrial biogenesis	50	2.93e-01	6.01e-01	0.2120	3.99e-02	0.159000	3.89e-02	-1.19e-01	-0.047700	0.626000	0.05270	0.635000	1.44e-01	5.61e-01
NEP/NS2 Interacts with the Cellular Export Machinery	28	2.94e-01	6.02e-01	0.2400	-9.80e-02	0.031300	1.08e-01	1.31e-01	0.135000	0.370000	0.77400	0.322000	2.31e-01	2.17e-01
Post-translational protein modification	860	2.96e-01	6.06e-01	0.0461	-7.98e-03	0.004610	1.95e-02	3.71e-02	0.016700	0.699000	0.82300	0.345000	7.16e-02	4.17e-01
Golgi-to-ER retrograde transport	91	2.97e-01	6.06e-01	0.1280	-3.70e-02	0.000499	1.09e-01	9.14e-03	0.056800	0.542000	0.99300	0.073800	8.81e-01	3.51e-01
MAPK1/MAPK3 signaling	153	2.98e-01	6.06e-01	0.1290	8.31e-03	0.055700	6.99e-02	-3.23e-02	-0.087000	0.860000	0.23700	0.137000	4.93e-01	6.44e-02
MET promotes cell motility	12	2.98e-01	6.06e-01	0.4470	-5.75e-02	-0.153000	3.60e-02	-3.39e-01	-0.238000	0.730000	0.36000	0.829000	4.20e-02	1.53e-01
Synthesis of PC	21	2.99e-01	6.07e-01	0.2440	6.99e-02	-0.002870	1.69e-01	6.37e-02	-0.149000	0.579000	0.98200	0.181000	6.13e-01	2.37e-01
Telomere C-strand (Lagging Strand) Synthesis	27	2.99e-01	6.07e-01	0.3590	-2.45e-01	-0.073900	1.80e-01	-9.03e-02	-0.153000	0.027700	0.50700	0.106000	4.17e-01	1.70e-01
RNA Polymerase I Transcription Initiation	38	3.02e-01	6.11e-01	0.1650	6.37e-02	-0.026200	1.25e-01	-7.92e-02	0.025000	0.497000	0.78000	0.183000	3.99e-01	7.90e-01
Cell death signalling via NRAGE, NRIF and NADE	40	3.03e-01	6.11e-01	0.1840	-6.38e-02	0.058200	-1.26e-01	8.30e-02	0.062200	0.486000	0.52500	0.170000	3.64e-01	4.96e-01
SUMOylation of SUMOylation proteins	30	3.03e-01	6.11e-01	0.2300	-9.78e-02	0.022100	1.49e-01	9.85e-02	0.105000	0.354000	0.83500	0.157000	3.51e-01	3.21e-01
Signaling by PDGFR in disease	15	3.04e-01	6.11e-01	0.3080	2.86e-01	0.076300	6.55e-02	-1.83e-02	0.050500	0.055200	0.60900	0.661000	9.02e-01	7.35e-01
Other interleukin signaling	16	3.04e-01	6.11e-01	0.3250	-2.08e-02	-0.220000	-6.96e-02	-2.08e-01	-0.091900	0.886000	0.12700	0.630000	1.49e-01	5.25e-01
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	16	3.07e-01	6.15e-01	0.3420	-1.66e-01	-0.017400	2.45e-01	7.89e-02	-0.150000	0.251000	0.90400	0.089500	5.85e-01	3.00e-01
VEGFR2 mediated cell proliferation	16	3.08e-01	6.15e-01	0.3870	6.12e-02	0.046600	1.49e-02	-2.58e-01	-0.277000	0.672000	0.74700	0.918000	7.36e-02	5.54e-02
DARPP-32 events	18	3.08e-01	6.15e-01	0.3090	1.85e-01	0.179000	-5.93e-02	-1.61e-01	0.014700	0.175000	0.19000	0.663000	2.39e-01	9.14e-01
mRNA decay by 5’ to 3’ exoribonuclease	14	3.09e-01	6.15e-01	0.3070	-6.13e-02	0.127000	-1.20e-01	2.39e-01	0.053000	0.691000	0.41000	0.436000	1.22e-01	7.31e-01
RAF/MAP kinase cascade	148	3.09e-01	6.15e-01	0.1240	8.34e-03	0.053400	7.23e-02	-1.98e-02	-0.082800	0.862000	0.26400	0.131000	6.79e-01	8.34e-02
Global Genome Nucleotide Excision Repair (GG-NER)	76	3.10e-01	6.15e-01	0.1970	1.50e-02	-0.095900	-2.01e-02	1.33e-01	0.106000	0.821000	0.14900	0.762000	4.57e-02	1.10e-01
Mitochondrial tRNA aminoacylation	16	3.10e-01	6.15e-01	0.3370	-2.14e-01	-0.159000	1.29e-01	-5.37e-02	0.150000	0.138000	0.27100	0.373000	7.10e-01	2.98e-01
tRNA processing in the nucleus	50	3.12e-01	6.16e-01	0.1860	-1.04e-01	-0.012800	1.28e-01	7.96e-02	0.030500	0.202000	0.87600	0.117000	3.31e-01	7.10e-01
Depolymerisation of the Nuclear Lamina	11	3.13e-01	6.16e-01	0.4980	-1.05e-01	-0.168000	3.01e-01	-1.91e-01	-0.286000	0.548000	0.33400	0.084400	2.72e-01	1.00e-01
HDR through Single Strand Annealing (SSA)	32	3.13e-01	6.16e-01	0.2220	-1.61e-01	-0.048100	8.75e-02	6.90e-02	-0.092900	0.115000	0.63800	0.392000	5.00e-01	3.64e-01
Resolution of Abasic Sites (AP sites)	31	3.13e-01	6.16e-01	0.1810	-1.47e-01	0.027000	-4.94e-03	8.01e-02	-0.061100	0.156000	0.79500	0.962000	4.41e-01	5.56e-01
Platelet homeostasis	45	3.13e-01	6.16e-01	0.2130	9.46e-02	0.126000	-6.65e-02	-1.19e-01	-0.044800	0.273000	0.14300	0.441000	1.68e-01	6.04e-01
Activation of BAD and translocation to mitochondria	14	3.14e-01	6.16e-01	0.3660	-3.94e-02	0.091300	1.30e-01	-3.20e-01	-0.067700	0.799000	0.55500	0.401000	3.82e-02	6.61e-01
Signaling by Insulin receptor	40	3.15e-01	6.17e-01	0.1660	-3.03e-02	0.091600	-1.13e-01	5.89e-02	-0.046000	0.741000	0.31700	0.217000	5.20e-01	6.15e-01
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	48	3.15e-01	6.17e-01	0.2650	-8.71e-02	0.046700	3.68e-02	-1.68e-01	-0.176000	0.297000	0.57600	0.659000	4.48e-02	3.50e-02
Transcriptional Regulation by TP53	273	3.18e-01	6.21e-01	0.0937	-5.07e-02	-0.064100	3.24e-02	1.36e-02	0.029700	0.153000	0.07060	0.361000	7.01e-01	4.02e-01
Ovarian tumor domain proteases	28	3.23e-01	6.30e-01	0.2640	3.55e-02	-0.017400	-1.32e-01	3.12e-02	0.223000	0.745000	0.87400	0.229000	7.75e-01	4.11e-02
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	21	3.24e-01	6.30e-01	0.3650	3.88e-02	0.177000	1.10e-01	-2.21e-01	-0.199000	0.758000	0.15900	0.381000	8.04e-02	1.15e-01
Metabolism of steroid hormones	13	3.25e-01	6.31e-01	0.2740	-1.14e-01	0.137000	5.77e-02	-1.37e-01	0.145000	0.476000	0.39300	0.719000	3.92e-01	3.65e-01
RHOJ GTPase cycle	34	3.29e-01	6.31e-01	0.2020	-1.82e-02	0.185000	-4.56e-02	-1.09e-02	0.063000	0.854000	0.06150	0.646000	9.13e-01	5.25e-01
Cyclin D associated events in G1	40	3.30e-01	6.31e-01	0.1780	1.72e-01	-0.016800	2.98e-02	1.50e-02	0.025400	0.060600	0.85400	0.744000	8.70e-01	7.81e-01
G1 Phase	40	3.30e-01	6.31e-01	0.1780	1.72e-01	-0.016800	2.98e-02	1.50e-02	0.025400	0.060600	0.85400	0.744000	8.70e-01	7.81e-01
Sema3A PAK dependent Axon repulsion	11	3.30e-01	6.31e-01	0.3820	-9.24e-02	-0.268000	-1.85e-01	-1.77e-01	-0.008850	0.596000	0.12300	0.289000	3.08e-01	9.59e-01
TBC/RABGAPs	39	3.30e-01	6.31e-01	0.2660	-2.02e-01	-0.011200	1.12e-01	-5.59e-02	-0.119000	0.029000	0.90400	0.228000	5.47e-01	2.00e-01
Assembly Of The HIV Virion	13	3.30e-01	6.31e-01	0.4430	-4.06e-02	-0.112000	-2.05e-01	2.94e-01	0.232000	0.800000	0.48300	0.201000	6.69e-02	1.47e-01
Formation of Incision Complex in GG-NER	36	3.31e-01	6.31e-01	0.3030	1.60e-01	-0.056200	-9.69e-02	1.90e-01	0.132000	0.096500	0.56000	0.315000	4.86e-02	1.72e-01
Gap-filling DNA repair synthesis and ligation in GG-NER	23	3.31e-01	6.31e-01	0.2960	-2.42e-01	-0.123000	8.67e-02	4.43e-02	0.065700	0.044900	0.30600	0.472000	7.13e-01	5.85e-01
Smooth Muscle Contraction	19	3.32e-01	6.31e-01	0.3680	-2.48e-01	0.006040	7.62e-02	-2.42e-01	-0.097700	0.061300	0.96400	0.565000	6.79e-02	4.61e-01
Paradoxical activation of RAF signaling by kinase inactive BRAF	29	3.32e-01	6.31e-01	0.2770	5.75e-02	0.193000	5.13e-02	-5.34e-02	-0.174000	0.592000	0.07170	0.633000	6.19e-01	1.05e-01
Signaling by RAS mutants	29	3.32e-01	6.31e-01	0.2770	5.75e-02	0.193000	5.13e-02	-5.34e-02	-0.174000	0.592000	0.07170	0.633000	6.19e-01	1.05e-01
Signaling by moderate kinase activity BRAF mutants	29	3.32e-01	6.31e-01	0.2770	5.75e-02	0.193000	5.13e-02	-5.34e-02	-0.174000	0.592000	0.07170	0.633000	6.19e-01	1.05e-01
Signaling downstream of RAS mutants	29	3.32e-01	6.31e-01	0.2770	5.75e-02	0.193000	5.13e-02	-5.34e-02	-0.174000	0.592000	0.07170	0.633000	6.19e-01	1.05e-01
Synthesis of PIPs at the early endosome membrane	11	3.32e-01	6.31e-01	0.3600	-1.89e-01	-0.048500	3.53e-02	2.84e-01	0.096700	0.277000	0.78100	0.839000	1.03e-01	5.79e-01
Signaling by SCF-KIT	32	3.33e-01	6.31e-01	0.2740	1.39e-02	0.205000	-9.09e-03	-1.28e-01	-0.127000	0.892000	0.04470	0.929000	2.09e-01	2.13e-01
Cholesterol biosynthesis	17	3.33e-01	6.31e-01	0.2820	-7.63e-02	0.030400	-1.87e-01	1.84e-01	0.062800	0.586000	0.82800	0.182000	1.89e-01	6.54e-01
RHOH GTPase cycle	27	3.36e-01	6.32e-01	0.2360	6.07e-02	0.114000	9.45e-02	1.72e-01	0.019800	0.585000	0.30500	0.396000	1.21e-01	8.59e-01
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	10	3.37e-01	6.32e-01	0.5540	-2.07e-01	0.143000	3.65e-01	-2.66e-01	-0.200000	0.257000	0.43300	0.045900	1.45e-01	2.74e-01
Golgi Cisternae Pericentriolar Stack Reorganization	13	3.37e-01	6.32e-01	0.4120	-2.43e-01	-0.245000	1.61e-01	9.37e-02	0.127000	0.129000	0.12600	0.315000	5.59e-01	4.27e-01
Citric acid cycle (TCA cycle)	19	3.37e-01	6.32e-01	0.4030	-1.55e-01	0.167000	1.08e-01	-2.37e-01	-0.206000	0.241000	0.20700	0.417000	7.41e-02	1.21e-01
Innate Immune System	582	3.37e-01	6.32e-01	0.0780	-2.44e-02	0.017600	4.90e-02	-2.97e-02	-0.043600	0.322000	0.47500	0.047200	2.29e-01	7.75e-02
Spry regulation of FGF signaling	15	3.37e-01	6.32e-01	0.3380	-1.26e-01	-0.153000	-2.19e-01	1.31e-01	0.097400	0.400000	0.30500	0.142000	3.78e-01	5.14e-01
Loss of Nlp from mitotic centrosomes	48	3.39e-01	6.33e-01	0.1890	-2.37e-02	-0.125000	1.27e-01	4.87e-02	0.029600	0.776000	0.13500	0.128000	5.60e-01	7.23e-01
Loss of proteins required for interphase microtubule organization from the centrosome	48	3.39e-01	6.33e-01	0.1890	-2.37e-02	-0.125000	1.27e-01	4.87e-02	0.029600	0.776000	0.13500	0.128000	5.60e-01	7.23e-01
mRNA Capping	25	3.44e-01	6.40e-01	0.2630	4.91e-02	-0.142000	4.82e-02	7.20e-02	0.198000	0.671000	0.22100	0.676000	5.33e-01	8.74e-02
HCMV Early Events	48	3.44e-01	6.40e-01	0.2360	-1.29e-01	0.011300	1.83e-01	-4.36e-02	-0.058100	0.123000	0.89200	0.028100	6.02e-01	4.87e-01
Signaling by Receptor Tyrosine Kinases	273	3.45e-01	6.40e-01	0.1050	-2.51e-02	0.049300	1.85e-02	-5.69e-02	-0.066900	0.480000	0.16400	0.601000	1.09e-01	5.89e-02
Gap-filling DNA repair synthesis and ligation in TC-NER	54	3.46e-01	6.40e-01	0.1980	-8.06e-02	-0.145000	9.52e-02	5.10e-02	0.016000	0.306000	0.06590	0.227000	5.17e-01	8.40e-01
Signaling by ERBB2 KD Mutants	10	3.46e-01	6.40e-01	0.3540	2.24e-01	0.093700	-1.07e-01	-1.32e-01	0.194000	0.220000	0.60800	0.557000	4.69e-01	2.89e-01
Recruitment of NuMA to mitotic centrosomes	55	3.46e-01	6.40e-01	0.1890	-5.38e-02	-0.135000	1.18e-01	8.57e-03	0.017500	0.491000	0.08310	0.129000	9.13e-01	8.23e-01
Regulation of signaling by CBL	14	3.47e-01	6.40e-01	0.3380	-8.17e-02	0.278000	1.56e-01	3.69e-02	-0.068200	0.597000	0.07220	0.313000	8.11e-01	6.59e-01
Mismatch Repair	13	3.47e-01	6.40e-01	0.2980	-1.29e-01	0.143000	1.24e-01	1.28e-01	-0.142000	0.419000	0.37200	0.441000	4.25e-01	3.76e-01
Signaling by FGFR1 in disease	23	3.49e-01	6.42e-01	0.2410	-5.38e-02	0.173000	-1.31e-01	-8.86e-02	-0.017000	0.655000	0.15100	0.279000	4.62e-01	8.88e-01
Regulation of TNFR1 signaling	30	3.50e-01	6.44e-01	0.2550	-9.08e-02	-0.070100	3.64e-03	1.84e-01	0.134000	0.390000	0.50700	0.973000	8.13e-02	2.04e-01
Processing of DNA double-strand break ends	52	3.51e-01	6.44e-01	0.1820	-1.37e-01	-0.073500	1.90e-02	7.25e-02	0.058500	0.088200	0.36000	0.813000	3.66e-01	4.66e-01
Metabolism of vitamins and cofactors	105	3.55e-01	6.49e-01	0.1220	4.65e-03	-0.054500	4.51e-02	-2.97e-02	-0.094300	0.935000	0.33600	0.426000	6.01e-01	9.61e-02
Cargo concentration in the ER	19	3.55e-01	6.49e-01	0.3770	-1.56e-02	-0.185000	-1.43e-01	2.27e-01	0.188000	0.907000	0.16300	0.282000	8.66e-02	1.56e-01
Josephin domain DUBs	11	3.58e-01	6.54e-01	0.3450	-1.33e-01	0.110000	-1.22e-01	1.34e-01	0.238000	0.444000	0.53000	0.485000	4.43e-01	1.71e-01
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	12	3.60e-01	6.57e-01	0.3090	4.03e-02	-0.229000	1.58e-01	-1.19e-01	0.049800	0.809000	0.17100	0.345000	4.77e-01	7.65e-01
Uptake and actions of bacterial toxins	18	3.61e-01	6.58e-01	0.3290	2.71e-01	0.017600	-7.44e-02	4.16e-02	0.164000	0.046400	0.89700	0.585000	7.60e-01	2.28e-01
Interleukin-7 signaling	14	3.63e-01	6.60e-01	0.3730	2.36e-01	0.247000	1.32e-02	-1.22e-01	-0.086900	0.126000	0.10900	0.932000	4.31e-01	5.73e-01
Rab regulation of trafficking	85	3.64e-01	6.60e-01	0.1440	-1.28e-01	0.003570	-4.33e-05	-5.01e-02	-0.042700	0.042500	0.95500	0.999000	4.26e-01	4.98e-01
GAB1 signalosome	10	3.66e-01	6.63e-01	0.4670	6.13e-02	0.059000	1.08e-01	-3.64e-01	-0.258000	0.737000	0.74700	0.554000	4.64e-02	1.57e-01
Centrosome maturation	56	3.69e-01	6.65e-01	0.1860	-6.13e-02	-0.125000	1.22e-01	1.89e-03	0.018000	0.428000	0.10700	0.113000	9.80e-01	8.16e-01
Recruitment of mitotic centrosome proteins and complexes	56	3.69e-01	6.65e-01	0.1860	-6.13e-02	-0.125000	1.22e-01	1.89e-03	0.018000	0.428000	0.10700	0.113000	9.80e-01	8.16e-01
Factors involved in megakaryocyte development and platelet production	83	3.69e-01	6.65e-01	0.1490	7.56e-02	0.079700	3.45e-02	-7.71e-02	-0.055100	0.235000	0.21100	0.588000	2.26e-01	3.87e-01
RHOQ GTPase cycle	36	3.70e-01	6.65e-01	0.2360	2.34e-02	0.098100	-1.51e-01	7.50e-02	0.130000	0.808000	0.30900	0.118000	4.36e-01	1.77e-01
Inhibition of DNA recombination at telomere	17	3.72e-01	6.69e-01	0.4150	-1.75e-01	-0.079000	1.19e-01	-1.83e-01	-0.296000	0.212000	0.57300	0.396000	1.92e-01	3.44e-02
Signaling by Retinoic Acid	17	3.73e-01	6.70e-01	0.3580	9.75e-02	0.026700	-3.20e-01	8.95e-02	0.085900	0.487000	0.84900	0.022500	5.23e-01	5.40e-01
Transcriptional Regulation by VENTX	25	3.75e-01	6.70e-01	0.3150	2.32e-01	-0.023700	-9.05e-02	1.71e-01	0.088200	0.045200	0.83800	0.434000	1.40e-01	4.45e-01
Antigen processing: Ubiquitination & Proteasome degradation	226	3.75e-01	6.70e-01	0.0900	6.39e-02	0.038800	1.72e-02	2.74e-02	0.038400	0.100000	0.31800	0.657000	4.80e-01	3.23e-01
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	16	3.81e-01	6.80e-01	0.4190	-2.93e-01	-0.205000	1.10e-01	-1.43e-01	-0.122000	0.042500	0.15500	0.448000	3.21e-01	3.97e-01
CD28 co-stimulation	27	3.85e-01	6.86e-01	0.2400	-1.26e-01	0.001120	1.49e-02	-2.03e-01	-0.015500	0.257000	0.99200	0.893000	6.77e-02	8.89e-01
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	26	3.87e-01	6.88e-01	0.2330	-1.20e-01	0.002240	1.16e-01	1.05e-01	0.124000	0.288000	0.98400	0.308000	3.56e-01	2.75e-01
Regulation of Glucokinase by Glucokinase Regulatory Protein	26	3.87e-01	6.88e-01	0.2330	-1.20e-01	0.002240	1.16e-01	1.05e-01	0.124000	0.288000	0.98400	0.308000	3.56e-01	2.75e-01
Nonhomologous End-Joining (NHEJ)	27	3.88e-01	6.88e-01	0.2300	-1.78e-01	-0.057700	7.44e-03	9.30e-02	0.096400	0.110000	0.60400	0.947000	4.03e-01	3.86e-01
Cargo recognition for clathrin-mediated endocytosis	64	3.89e-01	6.89e-01	0.1690	-8.65e-02	-0.095300	-4.91e-02	7.04e-02	0.067500	0.232000	0.18800	0.498000	3.31e-01	3.51e-01
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	10	3.90e-01	6.89e-01	0.4700	-7.77e-02	0.227000	2.56e-02	-3.55e-01	-0.193000	0.671000	0.21500	0.889000	5.19e-02	2.91e-01
SLC-mediated transmembrane transport	90	3.91e-01	6.90e-01	0.1830	9.91e-02	0.088500	-8.64e-02	6.46e-02	0.066000	0.105000	0.14800	0.158000	2.90e-01	2.80e-01
Regulation of innate immune responses to cytosolic DNA	11	3.91e-01	6.90e-01	0.4860	7.06e-02	-0.030600	-2.37e-01	3.53e-01	0.223000	0.685000	0.86100	0.174000	4.29e-02	2.01e-01
EPHB-mediated forward signaling	25	3.92e-01	6.90e-01	0.3040	-8.13e-02	-0.008530	-1.12e-02	-1.80e-01	-0.231000	0.482000	0.94100	0.923000	1.20e-01	4.58e-02
Polymerase switching on the C-strand of the telomere	20	3.94e-01	6.91e-01	0.3740	-1.94e-01	-0.148000	2.43e-01	-1.15e-01	-0.088900	0.134000	0.25200	0.060500	3.72e-01	4.92e-01
SUMOylation of immune response proteins	10	3.94e-01	6.91e-01	0.4360	2.85e-01	0.210000	1.83e-02	2.51e-01	0.040900	0.119000	0.25000	0.920000	1.69e-01	8.23e-01
RAB geranylgeranylation	39	3.95e-01	6.93e-01	0.1580	-8.59e-02	0.097700	-8.07e-03	8.29e-02	0.032500	0.354000	0.29100	0.931000	3.71e-01	7.26e-01
Regulation of BACH1 activity	11	3.98e-01	6.95e-01	0.5330	2.05e-01	-0.086200	-1.90e-01	2.46e-01	0.371000	0.240000	0.62100	0.275000	1.58e-01	3.30e-02
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	13	3.98e-01	6.95e-01	0.3350	2.51e-01	-0.154000	-5.09e-03	1.24e-01	0.099800	0.118000	0.33600	0.975000	4.40e-01	5.33e-01
Pre-NOTCH Processing in Golgi	15	3.98e-01	6.95e-01	0.4000	-2.08e-01	-0.037200	1.59e-01	-9.15e-02	-0.285000	0.162000	0.80300	0.288000	5.40e-01	5.60e-02
MHC class II antigen presentation	64	4.00e-01	6.96e-01	0.1640	5.19e-02	-0.063500	-1.22e-02	1.37e-01	0.036000	0.473000	0.38000	0.866000	5.79e-02	6.19e-01
Interleukin-1 signaling	74	4.00e-01	6.96e-01	0.1560	-8.12e-02	-0.070400	2.85e-02	5.88e-02	0.092200	0.228000	0.29600	0.673000	3.83e-01	1.71e-01
Retinoid metabolism and transport	11	4.01e-01	6.96e-01	0.3630	1.06e-01	-0.199000	-2.75e-01	6.41e-02	-0.029500	0.542000	0.25300	0.114000	7.13e-01	8.66e-01
NGF-stimulated transcription	25	4.01e-01	6.96e-01	0.3350	-1.70e-01	-0.055100	2.15e-01	-1.65e-01	-0.082200	0.142000	0.63400	0.063100	1.53e-01	4.77e-01
Transcription of the HIV genome	50	4.02e-01	6.96e-01	0.2020	-3.66e-03	-0.121000	3.72e-02	9.92e-02	0.123000	0.964000	0.14100	0.649000	2.25e-01	1.33e-01
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	56	4.04e-01	6.98e-01	0.1760	-4.03e-03	-0.111000	5.77e-02	1.10e-01	0.058400	0.958000	0.15100	0.456000	1.57e-01	4.51e-01
SUMOylation of transcription cofactors	35	4.04e-01	6.98e-01	0.2100	8.15e-02	0.181000	1.91e-02	-1.61e-02	0.063600	0.404000	0.06380	0.845000	8.69e-01	5.16e-01
Transcriptional regulation by RUNX3	73	4.05e-01	6.99e-01	0.1540	-2.84e-02	-0.058400	5.05e-02	1.15e-01	0.060800	0.676000	0.38900	0.456000	9.05e-02	3.70e-01
Interleukin-20 family signaling	13	4.07e-01	6.99e-01	0.3410	2.98e-01	0.154000	3.50e-02	-2.24e-02	-0.040000	0.062500	0.33700	0.827000	8.89e-01	8.03e-01
Caspase activation via extrinsic apoptotic signalling pathway	15	4.07e-01	6.99e-01	0.3740	-3.15e-01	-0.110000	1.67e-01	-2.62e-02	-0.008050	0.034700	0.46100	0.262000	8.61e-01	9.57e-01
IRS-related events triggered by IGF1R	21	4.09e-01	7.01e-01	0.2890	-1.18e-01	0.070100	-7.65e-02	-1.59e-01	-0.183000	0.350000	0.57800	0.544000	2.07e-01	1.47e-01
Organelle biogenesis and maintenance	184	4.09e-01	7.01e-01	0.0851	-4.56e-02	-0.024200	3.84e-02	4.03e-03	0.055500	0.289000	0.57300	0.372000	9.25e-01	1.96e-01
Dual Incision in GG-NER	35	4.12e-01	7.03e-01	0.2580	-1.48e-02	-0.177000	-3.36e-02	1.27e-01	0.134000	0.879000	0.07070	0.731000	1.94e-01	1.69e-01
TP53 Regulates Metabolic Genes	60	4.12e-01	7.03e-01	0.1350	-1.22e-01	-0.004950	-1.21e-02	3.25e-02	0.046800	0.102000	0.94700	0.871000	6.64e-01	5.32e-01
Integration of energy metabolism	56	4.12e-01	7.03e-01	0.1730	2.76e-02	0.044000	-1.11e-02	-1.51e-01	-0.066600	0.722000	0.57000	0.886000	5.14e-02	3.89e-01
Cobalamin (Cbl, vitamin B12) transport and metabolism	10	4.13e-01	7.03e-01	0.3390	-2.47e-02	0.206000	1.77e-01	1.92e-01	-0.062600	0.893000	0.26000	0.332000	2.94e-01	7.32e-01
Disassembly of the destruction complex and recruitment of AXIN to the membrane	26	4.16e-01	7.07e-01	0.2090	1.35e-01	-0.013600	-1.06e-01	-1.11e-01	0.043100	0.234000	0.90400	0.349000	3.29e-01	7.04e-01
Interleukin-3, Interleukin-5 and GM-CSF signaling	29	4.16e-01	7.07e-01	0.2690	-9.76e-02	0.144000	1.56e-01	-4.77e-02	-0.125000	0.363000	0.18100	0.146000	6.57e-01	2.44e-01
Epigenetic regulation of gene expression	70	4.18e-01	7.09e-01	0.1210	2.76e-02	-0.015800	9.16e-02	1.68e-02	0.070100	0.690000	0.82000	0.186000	8.08e-01	3.12e-01
Signaling by NOTCH	128	4.20e-01	7.11e-01	0.1070	-3.94e-02	-0.012600	5.99e-02	5.92e-02	0.052400	0.443000	0.80600	0.243000	2.50e-01	3.08e-01
Adrenaline,noradrenaline inhibits insulin secretion	11	4.21e-01	7.11e-01	0.3250	4.83e-02	0.196000	2.32e-01	1.21e-02	0.107000	0.782000	0.26100	0.183000	9.44e-01	5.40e-01
FCERI mediated Ca+2 mobilization	23	4.22e-01	7.11e-01	0.3010	-1.75e-02	0.124000	2.03e-01	-1.54e-01	-0.101000	0.885000	0.30300	0.091900	2.02e-01	4.04e-01
Signaling by VEGF	71	4.22e-01	7.11e-01	0.1990	-3.26e-02	0.005170	7.19e-02	-1.40e-01	-0.116000	0.636000	0.94000	0.296000	4.17e-02	9.09e-02
Developmental Biology	438	4.23e-01	7.11e-01	0.0645	-1.11e-03	-0.050800	1.65e-02	2.43e-02	0.026600	0.969000	0.07160	0.558000	3.89e-01	3.47e-01
E3 ubiquitin ligases ubiquitinate target proteins	39	4.23e-01	7.11e-01	0.2090	-1.87e-01	-0.056300	3.47e-02	-9.19e-03	-0.064900	0.043900	0.54300	0.708000	9.21e-01	4.84e-01
Negative regulation of FLT3	13	4.29e-01	7.20e-01	0.3400	-1.88e-01	-0.062000	2.22e-01	1.37e-01	0.092700	0.241000	0.69900	0.166000	3.92e-01	5.63e-01
Negative regulation of the PI3K/AKT network	53	4.30e-01	7.20e-01	0.2130	-6.93e-02	-0.000657	2.25e-03	-1.61e-01	-0.120000	0.383000	0.99300	0.977000	4.26e-02	1.30e-01
Signaling by FLT3 fusion proteins	16	4.31e-01	7.20e-01	0.3550	-4.34e-03	0.047300	-4.47e-02	-2.53e-01	-0.241000	0.976000	0.74300	0.757000	8.03e-02	9.56e-02
Transcriptional activation of mitochondrial biogenesis	36	4.32e-01	7.20e-01	0.2250	5.85e-02	0.207000	3.32e-02	-4.03e-02	-0.041700	0.544000	0.03160	0.731000	6.76e-01	6.65e-01
ESR-mediated signaling	106	4.32e-01	7.20e-01	0.1120	-3.09e-02	0.053800	8.53e-02	-3.42e-02	0.014100	0.584000	0.34000	0.131000	5.45e-01	8.03e-01
Formation of tubulin folding intermediates by CCT/TriC	13	4.33e-01	7.20e-01	0.2920	-2.53e-02	0.031500	9.82e-03	2.87e-01	0.034000	0.874000	0.84400	0.951000	7.29e-02	8.32e-01
Regulation of KIT signaling	10	4.34e-01	7.20e-01	0.5390	-1.69e-01	0.170000	3.05e-01	-2.47e-01	-0.281000	0.354000	0.35300	0.094700	1.76e-01	1.24e-01
Effects of PIP2 hydrolysis	18	4.34e-01	7.20e-01	0.2330	-6.50e-02	0.067100	6.86e-02	-1.95e-01	0.051000	0.633000	0.62200	0.614000	1.51e-01	7.08e-01
RHOG GTPase cycle	45	4.34e-01	7.20e-01	0.2170	6.00e-02	0.109000	-5.83e-02	1.42e-01	0.090200	0.487000	0.20600	0.499000	9.93e-02	2.96e-01
DNA Double Strand Break Response	33	4.37e-01	7.23e-01	0.2060	-1.47e-01	-0.083400	-4.38e-02	6.34e-02	0.089800	0.145000	0.40800	0.663000	5.29e-01	3.72e-01
Platelet degranulation	46	4.38e-01	7.23e-01	0.1640	5.33e-02	-0.023900	-1.27e-01	-5.17e-02	-0.069200	0.532000	0.78000	0.137000	5.45e-01	4.17e-01
FGFR1 mutant receptor activation	19	4.38e-01	7.23e-01	0.2140	-1.26e-01	0.151000	-6.94e-02	-2.54e-03	0.048100	0.341000	0.25400	0.601000	9.85e-01	7.17e-01
Signaling by NTRK2 (TRKB)	15	4.41e-01	7.26e-01	0.3330	5.83e-02	-0.004450	-1.91e-02	-2.60e-01	-0.199000	0.696000	0.97600	0.898000	8.09e-02	1.83e-01
Insulin receptor signalling cascade	25	4.41e-01	7.26e-01	0.1990	-1.03e-01	0.039400	-1.04e-01	-3.45e-02	-0.125000	0.373000	0.73300	0.366000	7.65e-01	2.81e-01
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	32	4.42e-01	7.27e-01	0.2110	-1.31e-01	-0.082400	-6.14e-02	6.27e-02	0.115000	0.202000	0.42000	0.548000	5.40e-01	2.61e-01
Sealing of the nuclear envelope (NE) by ESCRT-III	16	4.46e-01	7.31e-01	0.2640	3.34e-02	0.037400	1.39e-01	2.18e-01	0.015700	0.817000	0.79600	0.334000	1.31e-01	9.13e-01
Phase I - Functionalization of compounds	29	4.48e-01	7.34e-01	0.1900	8.09e-02	0.057300	3.96e-02	-1.56e-01	-0.012000	0.451000	0.59300	0.712000	1.45e-01	9.11e-01
Interleukin-37 signaling	16	4.49e-01	7.36e-01	0.3550	8.08e-03	0.138000	-1.18e-02	-2.72e-01	-0.181000	0.955000	0.34000	0.935000	5.93e-02	2.09e-01
G alpha (z) signalling events	22	4.52e-01	7.38e-01	0.2730	-1.16e-01	0.188000	6.46e-02	-1.30e-01	-0.067900	0.345000	0.12700	0.600000	2.91e-01	5.81e-01
Glyoxylate metabolism and glycine degradation	19	4.54e-01	7.38e-01	0.3240	-8.47e-02	-0.162000	-1.13e-01	1.68e-01	0.175000	0.523000	0.22100	0.393000	2.06e-01	1.86e-01
Plasma lipoprotein assembly, remodeling, and clearance	33	4.54e-01	7.38e-01	0.2170	-5.69e-02	-0.164000	-8.85e-02	8.98e-02	0.028400	0.572000	0.10300	0.379000	3.73e-01	7.78e-01
Mitochondrial protein import	42	4.54e-01	7.38e-01	0.1450	3.72e-02	-0.049800	1.06e-01	-7.73e-02	0.008880	0.677000	0.57700	0.236000	3.87e-01	9.21e-01
Signaling by RAF1 mutants	25	4.54e-01	7.38e-01	0.2770	-1.46e-02	0.182000	5.38e-02	-7.41e-02	-0.187000	0.899000	0.11500	0.642000	5.21e-01	1.05e-01
XBP1(S) activates chaperone genes	36	4.56e-01	7.40e-01	0.2110	-1.30e-01	0.053200	1.57e-01	1.32e-03	-0.019200	0.179000	0.58100	0.103000	9.89e-01	8.42e-01
Sema4D in semaphorin signaling	13	4.57e-01	7.40e-01	0.2630	1.39e-01	-0.120000	7.57e-02	-1.52e-01	-0.080800	0.385000	0.45300	0.637000	3.43e-01	6.14e-01
VEGFA-VEGFR2 Pathway	69	4.62e-01	7.44e-01	0.1910	-3.37e-02	-0.010900	4.92e-02	-1.35e-01	-0.121000	0.629000	0.87600	0.481000	5.23e-02	8.35e-02
Recycling pathway of L1	15	4.63e-01	7.44e-01	0.2600	2.65e-02	0.027200	-1.81e-01	-3.56e-02	-0.180000	0.859000	0.85600	0.226000	8.12e-01	2.27e-01
RNA Polymerase I Transcription Termination	23	4.63e-01	7.44e-01	0.2110	9.27e-02	-0.132000	9.74e-02	4.47e-02	0.084800	0.442000	0.27400	0.419000	7.11e-01	4.82e-01
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	21	4.64e-01	7.44e-01	0.2850	2.43e-01	0.042000	-6.47e-02	3.41e-02	0.123000	0.054000	0.73900	0.608000	7.87e-01	3.30e-01
Toll Like Receptor 4 (TLR4) Cascade	87	4.64e-01	7.44e-01	0.1220	-9.04e-02	0.066500	2.36e-02	-3.22e-02	-0.024400	0.146000	0.28500	0.705000	6.05e-01	6.95e-01
FOXO-mediated transcription of cell cycle genes	12	4.65e-01	7.44e-01	0.3920	-9.37e-02	-0.204000	2.09e-01	-2.16e-01	-0.112000	0.574000	0.22100	0.209000	1.95e-01	5.02e-01
COPI-independent Golgi-to-ER retrograde traffic	28	4.65e-01	7.44e-01	0.2480	-4.04e-02	0.088800	2.03e-01	-9.19e-02	-0.049700	0.712000	0.41600	0.063700	4.00e-01	6.49e-01
RNA Pol II CTD phosphorylation and interaction with CE	23	4.65e-01	7.44e-01	0.2280	3.70e-02	-0.174000	3.67e-02	6.12e-03	0.138000	0.759000	0.14900	0.761000	9.60e-01	2.53e-01
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	23	4.65e-01	7.44e-01	0.2280	3.70e-02	-0.174000	3.67e-02	6.12e-03	0.138000	0.759000	0.14900	0.761000	9.60e-01	2.53e-01
MAP3K8 (TPL2)-dependent MAPK1/3 activation	13	4.68e-01	7.47e-01	0.3770	-1.48e-02	-0.056800	-1.33e-01	1.41e-01	0.317000	0.927000	0.72300	0.405000	3.78e-01	4.75e-02
APC/C:Cdc20 mediated degradation of Cyclin B	19	4.69e-01	7.49e-01	0.3820	1.59e-01	-0.056900	-1.37e-01	2.61e-01	0.176000	0.230000	0.66800	0.302000	4.94e-02	1.85e-01
G beta:gamma signalling through PI3Kgamma	14	4.74e-01	7.52e-01	0.2910	-4.31e-02	0.241000	1.52e-01	-1.13e-02	0.043400	0.780000	0.11900	0.326000	9.42e-01	7.78e-01
Signaling by ERBB2 in Cancer	11	4.75e-01	7.52e-01	0.2710	1.16e-01	0.113000	-1.82e-02	-1.89e-01	0.107000	0.505000	0.51700	0.917000	2.78e-01	5.40e-01
RAC3 GTPase cycle	55	4.76e-01	7.52e-01	0.1740	1.09e-01	0.064500	3.15e-02	7.66e-02	0.085000	0.161000	0.40900	0.687000	3.26e-01	2.76e-01
Sema4D induced cell migration and growth-cone collapse	11	4.77e-01	7.52e-01	0.2810	1.54e-01	-0.109000	1.05e-01	-1.58e-01	-0.087600	0.378000	0.53200	0.547000	3.64e-01	6.15e-01
Signal transduction by L1	11	4.78e-01	7.52e-01	0.2810	1.48e-01	-0.100000	-1.04e-01	-8.65e-03	-0.190000	0.396000	0.56500	0.551000	9.60e-01	2.74e-01
Initiation of Nuclear Envelope (NE) Reformation	17	4.78e-01	7.52e-01	0.2600	4.13e-03	-0.076200	2.22e-01	1.04e-01	0.044500	0.976000	0.58700	0.114000	4.59e-01	7.51e-01
Nuclear Events (kinase and transcription factor activation)	42	4.79e-01	7.52e-01	0.2530	-1.37e-01	-0.015600	1.72e-01	-7.89e-02	-0.096500	0.126000	0.86100	0.054300	3.77e-01	2.80e-01
RHO GTPases activate CIT	14	4.79e-01	7.52e-01	0.4320	-2.22e-01	-0.042600	2.87e-01	-1.11e-01	-0.203000	0.151000	0.78300	0.063100	4.73e-01	1.89e-01
Leading Strand Synthesis	12	4.79e-01	7.52e-01	0.4020	-2.35e-01	-0.131000	2.97e-01	-2.65e-02	-0.006220	0.160000	0.43200	0.074800	8.74e-01	9.70e-01
Polymerase switching	12	4.79e-01	7.52e-01	0.4020	-2.35e-01	-0.131000	2.97e-01	-2.65e-02	-0.006220	0.160000	0.43200	0.074800	8.74e-01	9.70e-01
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	15	4.84e-01	7.52e-01	0.3530	3.05e-01	0.072300	-8.07e-02	1.31e-01	0.053600	0.040900	0.62800	0.588000	3.80e-01	7.20e-01
Molecules associated with elastic fibres	10	4.84e-01	7.52e-01	0.3410	-1.43e-01	-0.002860	3.49e-02	-3.07e-01	0.003250	0.433000	0.98800	0.849000	9.24e-02	9.86e-01
Formation of the Early Elongation Complex	25	4.85e-01	7.52e-01	0.2290	1.36e-01	-0.094200	-4.73e-03	4.72e-02	0.151000	0.239000	0.41500	0.967000	6.83e-01	1.90e-01
Formation of the HIV-1 Early Elongation Complex	25	4.85e-01	7.52e-01	0.2290	1.36e-01	-0.094200	-4.73e-03	4.72e-02	0.151000	0.239000	0.41500	0.967000	6.83e-01	1.90e-01
COPI-dependent Golgi-to-ER retrograde traffic	63	4.86e-01	7.52e-01	0.1440	-3.53e-02	-0.038900	6.62e-02	5.42e-02	0.104000	0.628000	0.59400	0.364000	4.58e-01	1.54e-01
APC truncation mutants have impaired AXIN binding	12	4.86e-01	7.52e-01	0.3110	2.82e-01	-0.006610	4.32e-02	6.66e-02	0.106000	0.091300	0.96800	0.796000	6.90e-01	5.26e-01
AXIN missense mutants destabilize the destruction complex	12	4.86e-01	7.52e-01	0.3110	2.82e-01	-0.006610	4.32e-02	6.66e-02	0.106000	0.091300	0.96800	0.796000	6.90e-01	5.26e-01
Signaling by AMER1 mutants	12	4.86e-01	7.52e-01	0.3110	2.82e-01	-0.006610	4.32e-02	6.66e-02	0.106000	0.091300	0.96800	0.796000	6.90e-01	5.26e-01
Signaling by APC mutants	12	4.86e-01	7.52e-01	0.3110	2.82e-01	-0.006610	4.32e-02	6.66e-02	0.106000	0.091300	0.96800	0.796000	6.90e-01	5.26e-01
Signaling by AXIN mutants	12	4.86e-01	7.52e-01	0.3110	2.82e-01	-0.006610	4.32e-02	6.66e-02	0.106000	0.091300	0.96800	0.796000	6.90e-01	5.26e-01
Truncations of AMER1 destabilize the destruction complex	12	4.86e-01	7.52e-01	0.3110	2.82e-01	-0.006610	4.32e-02	6.66e-02	0.106000	0.091300	0.96800	0.796000	6.90e-01	5.26e-01
Programmed Cell Death	148	4.87e-01	7.52e-01	0.1010	-4.31e-02	-0.053800	4.40e-02	2.01e-02	0.054900	0.367000	0.26000	0.357000	6.74e-01	2.51e-01
Formation of RNA Pol II elongation complex	43	4.87e-01	7.52e-01	0.1670	-2.07e-02	-0.035400	1.09e-01	5.93e-02	0.104000	0.815000	0.68800	0.217000	5.01e-01	2.40e-01
RNA Polymerase II Transcription Elongation	43	4.87e-01	7.52e-01	0.1670	-2.07e-02	-0.035400	1.09e-01	5.93e-02	0.104000	0.815000	0.68800	0.217000	5.01e-01	2.40e-01
Platelet activation, signaling and aggregation	125	4.88e-01	7.53e-01	0.1490	-6.39e-02	0.039600	4.89e-02	-8.46e-02	-0.083400	0.219000	0.44600	0.346000	1.03e-01	1.09e-01
Generic Transcription Pathway	771	4.90e-01	7.55e-01	0.0453	-1.54e-02	-0.035400	-4.76e-03	-2.62e-03	0.023200	0.478000	0.10200	0.826000	9.04e-01	2.85e-01
Signaling by the B Cell Receptor (BCR)	87	4.91e-01	7.55e-01	0.1140	-6.15e-03	-0.021600	1.11e-01	-2.26e-03	0.015400	0.921000	0.72800	0.075400	9.71e-01	8.05e-01
RHO GTPase Effectors	184	4.92e-01	7.56e-01	0.1020	-6.34e-02	-0.022300	6.85e-02	3.02e-03	-0.035900	0.140000	0.60400	0.111000	9.44e-01	4.04e-01
IRS-mediated signalling	20	4.94e-01	7.57e-01	0.2700	-1.08e-01	0.068100	-6.83e-02	-1.28e-01	-0.188000	0.402000	0.59800	0.597000	3.23e-01	1.45e-01
O-linked glycosylation	39	4.96e-01	7.60e-01	0.1770	7.00e-02	0.011000	-1.54e-01	1.93e-02	-0.047600	0.450000	0.90600	0.095600	8.35e-01	6.07e-01
Apoptotic factor-mediated response	15	4.97e-01	7.60e-01	0.2270	-1.13e-01	0.091000	-1.20e-01	1.25e-01	0.021200	0.450000	0.54200	0.423000	4.02e-01	8.87e-01
Presynaptic phase of homologous DNA pairing and strand exchange	31	4.98e-01	7.60e-01	0.2030	-1.58e-01	-0.057900	8.01e-02	6.57e-02	-0.046300	0.128000	0.57800	0.440000	5.27e-01	6.56e-01
Positive epigenetic regulation of rRNA expression	38	4.99e-01	7.60e-01	0.1540	4.51e-02	0.058200	1.25e-01	-3.48e-02	0.037400	0.631000	0.53500	0.183000	7.11e-01	6.90e-01
Base Excision Repair	38	4.99e-01	7.60e-01	0.1780	-1.37e-01	0.014500	3.16e-02	2.62e-04	-0.108000	0.146000	0.87800	0.736000	9.98e-01	2.48e-01
Insulin processing	14	5.01e-01	7.60e-01	0.2560	2.07e-01	-0.008000	6.02e-03	-3.21e-02	0.148000	0.181000	0.95900	0.969000	8.35e-01	3.39e-01
Metabolism of folate and pterines	11	5.02e-01	7.60e-01	0.3950	-1.08e-01	0.246000	5.19e-02	-1.25e-01	-0.256000	0.535000	0.15800	0.766000	4.73e-01	1.41e-01
Homologous DNA Pairing and Strand Exchange	34	5.02e-01	7.60e-01	0.1950	-1.48e-01	-0.076300	6.55e-02	6.67e-02	-0.038000	0.136000	0.44200	0.509000	5.01e-01	7.01e-01
SUMOylation of DNA damage response and repair proteins	65	5.02e-01	7.60e-01	0.1500	-7.84e-02	-0.042200	1.09e-01	4.53e-02	0.025200	0.275000	0.55700	0.130000	5.28e-01	7.26e-01
Diseases associated with N-glycosylation of proteins	15	5.03e-01	7.62e-01	0.3510	-1.88e-01	-0.191000	2.26e-01	-1.73e-02	0.011900	0.208000	0.20000	0.129000	9.07e-01	9.36e-01
Pyruvate metabolism and Citric Acid (TCA) cycle	40	5.07e-01	7.66e-01	0.2040	2.88e-02	0.080300	-4.74e-03	-1.61e-01	-0.091200	0.753000	0.38000	0.959000	7.79e-02	3.19e-01
InlB-mediated entry of Listeria monocytogenes into host cell	11	5.07e-01	7.66e-01	0.4290	-4.41e-02	-0.121000	-1.22e-01	2.90e-01	0.260000	0.800000	0.48600	0.483000	9.56e-02	1.35e-01
Listeria monocytogenes entry into host cells	14	5.10e-01	7.69e-01	0.3380	-2.11e-02	-0.070600	-2.25e-01	2.06e-01	0.123000	0.891000	0.64800	0.145000	1.82e-01	4.25e-01
TCR signaling	84	5.11e-01	7.69e-01	0.1180	-5.82e-03	0.004740	1.17e-01	-1.25e-02	-0.000912	0.927000	0.94000	0.063300	8.43e-01	9.88e-01
Response to elevated platelet cytosolic Ca2+	50	5.11e-01	7.69e-01	0.1470	1.59e-02	-0.046600	-9.83e-02	-6.56e-02	-0.071800	0.846000	0.56900	0.230000	4.23e-01	3.81e-01
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	15	5.14e-01	7.71e-01	0.3240	8.55e-02	-0.149000	7.01e-02	2.11e-01	0.163000	0.567000	0.31700	0.638000	1.58e-01	2.76e-01
Senescence-Associated Secretory Phenotype (SASP)	39	5.15e-01	7.71e-01	0.2510	1.24e-01	-0.046700	-8.35e-02	1.63e-01	0.108000	0.180000	0.61400	0.367000	7.78e-02	2.43e-01
Glutathione conjugation	20	5.16e-01	7.71e-01	0.2440	1.03e-01	-0.068000	-1.37e-01	1.59e-01	-0.016500	0.425000	0.59900	0.290000	2.18e-01	8.98e-01
RNA Polymerase I Promoter Escape	25	5.16e-01	7.71e-01	0.2360	1.16e-01	-0.147000	4.34e-03	9.69e-02	0.107000	0.318000	0.20300	0.970000	4.02e-01	3.54e-01
Insulin receptor recycling	16	5.16e-01	7.71e-01	0.3210	6.19e-02	0.137000	-1.31e-01	2.27e-01	0.108000	0.668000	0.34200	0.364000	1.16e-01	4.53e-01
Regulation of IFNG signaling	13	5.17e-01	7.72e-01	0.2940	1.65e-01	0.099800	3.72e-02	-2.05e-01	-0.075400	0.303000	0.53300	0.817000	2.00e-01	6.38e-01
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	20	5.20e-01	7.74e-01	0.2740	-1.09e-01	-0.130000	9.20e-02	1.60e-01	0.110000	0.401000	0.31400	0.477000	2.17e-01	3.93e-01
Interferon Signaling	136	5.22e-01	7.75e-01	0.1410	-7.63e-02	-0.032500	8.36e-02	-5.27e-02	-0.057300	0.126000	0.51400	0.093700	2.90e-01	2.50e-01
Thromboxane signalling through TP receptor	12	5.23e-01	7.75e-01	0.3430	-2.72e-01	0.009430	2.08e-01	5.07e-03	0.011700	0.102000	0.95500	0.212000	9.76e-01	9.44e-01
IRE1alpha activates chaperones	37	5.23e-01	7.75e-01	0.1860	-1.04e-01	0.066200	1.37e-01	2.27e-02	-0.015000	0.276000	0.48700	0.151000	8.11e-01	8.75e-01
Biological oxidations	74	5.23e-01	7.75e-01	0.1580	1.19e-01	0.000491	-6.51e-02	2.60e-02	0.076700	0.076600	0.99400	0.334000	7.00e-01	2.55e-01
Glycerophospholipid biosynthesis	69	5.24e-01	7.75e-01	0.1500	8.21e-03	-0.017900	4.83e-02	-6.69e-02	-0.123000	0.906000	0.79800	0.489000	3.37e-01	7.72e-02
IGF1R signaling cascade	22	5.26e-01	7.75e-01	0.2660	-1.48e-01	0.060300	-3.25e-02	-1.41e-01	-0.156000	0.231000	0.62500	0.792000	2.53e-01	2.05e-01
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	22	5.26e-01	7.75e-01	0.2660	-1.48e-01	0.060300	-3.25e-02	-1.41e-01	-0.156000	0.231000	0.62500	0.792000	2.53e-01	2.05e-01
Lagging Strand Synthesis	17	5.26e-01	7.75e-01	0.3210	-2.53e-01	-0.058200	1.69e-01	-2.02e-03	-0.085000	0.071200	0.67800	0.227000	9.89e-01	5.44e-01
Activation of gene expression by SREBF (SREBP)	33	5.27e-01	7.76e-01	0.2050	2.68e-02	0.112000	-1.33e-01	9.51e-02	0.047500	0.790000	0.26800	0.186000	3.45e-01	6.37e-01
RHO GTPases activate PAKs	13	5.28e-01	7.76e-01	0.4150	-1.11e-01	-0.022500	7.30e-02	-2.47e-01	-0.306000	0.489000	0.88800	0.649000	1.23e-01	5.65e-02
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	13	5.31e-01	7.80e-01	0.4000	-2.19e-04	-0.208000	-7.33e-02	2.09e-01	0.261000	0.999000	0.19500	0.647000	1.92e-01	1.04e-01
Metabolism of steroids	80	5.33e-01	7.82e-01	0.1070	-2.51e-02	0.086400	-4.22e-02	2.09e-02	0.035300	0.698000	0.18300	0.515000	7.47e-01	5.86e-01
Beta-catenin independent WNT signaling	99	5.36e-01	7.85e-01	0.1170	-3.19e-02	-0.038700	5.54e-02	6.25e-02	0.065500	0.584000	0.50700	0.342000	2.84e-01	2.61e-01
Viral Messenger RNA Synthesis	38	5.41e-01	7.89e-01	0.1740	-1.22e-01	-0.017000	9.09e-02	4.39e-02	0.070600	0.192000	0.85600	0.333000	6.40e-01	4.52e-01
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	34	5.41e-01	7.89e-01	0.1800	-1.10e-01	0.027900	1.73e-02	-1.24e-02	-0.138000	0.266000	0.77800	0.861000	9.00e-01	1.65e-01
Vitamin B5 (pantothenate) metabolism	11	5.41e-01	7.89e-01	0.3710	-3.96e-02	-0.171000	2.34e-01	-1.62e-01	-0.160000	0.820000	0.32700	0.179000	3.51e-01	3.59e-01
Attenuation phase	19	5.41e-01	7.89e-01	0.2600	-6.83e-03	-0.210000	9.95e-02	1.01e-01	0.059200	0.959000	0.11300	0.453000	4.48e-01	6.55e-01
CLEC7A (Dectin-1) induces NFAT activation	11	5.43e-01	7.91e-01	0.4540	-7.73e-02	-0.001290	2.50e-01	-2.67e-01	-0.257000	0.657000	0.99400	0.151000	1.25e-01	1.40e-01
Processive synthesis on the lagging strand	13	5.47e-01	7.95e-01	0.3100	-2.66e-01	-0.034900	1.33e-01	5.81e-02	-0.054700	0.097300	0.82800	0.407000	7.17e-01	7.33e-01
Diseases of signal transduction by growth factor receptors and second messengers	261	5.49e-01	7.98e-01	0.0857	-4.41e-02	0.036100	4.61e-02	-3.41e-02	-0.028200	0.223000	0.31900	0.203000	3.46e-01	4.36e-01
Nucleobase biosynthesis	12	5.51e-01	7.99e-01	0.3170	2.08e-01	0.081900	9.42e-02	1.16e-01	0.167000	0.212000	0.62300	0.572000	4.85e-01	3.17e-01
Apoptosis	128	5.52e-01	7.99e-01	0.1030	-6.42e-02	-0.047300	4.01e-02	1.60e-02	0.048700	0.211000	0.35700	0.435000	7.55e-01	3.43e-01
RND2 GTPase cycle	32	5.56e-01	8.04e-01	0.2230	-1.01e-01	-0.150000	-4.00e-03	-9.34e-02	-0.090900	0.324000	0.14100	0.969000	3.61e-01	3.74e-01
Negative regulation of MAPK pathway	35	5.57e-01	8.04e-01	0.1860	9.90e-02	0.117000	-5.26e-02	3.91e-02	-0.082400	0.311000	0.22900	0.591000	6.89e-01	4.00e-01
Phospholipid metabolism	127	5.58e-01	8.04e-01	0.0976	1.24e-03	0.009660	1.06e-02	-2.60e-02	-0.092900	0.981000	0.85100	0.837000	6.14e-01	7.15e-02
NOTCH4 Intracellular Domain Regulates Transcription	14	5.58e-01	8.04e-01	0.3450	-1.42e-01	0.009130	2.97e-01	-2.82e-02	-0.098700	0.359000	0.95300	0.054400	8.55e-01	5.23e-01
The citric acid (TCA) cycle and respiratory electron transport	109	5.58e-01	8.04e-01	0.1090	-4.92e-02	-0.032600	8.45e-02	-3.19e-02	0.017700	0.376000	0.55800	0.129000	5.66e-01	7.50e-01
Fcgamma receptor (FCGR) dependent phagocytosis	61	5.60e-01	8.05e-01	0.1740	-7.11e-02	-0.112000	4.59e-02	-7.39e-02	-0.071500	0.338000	0.13200	0.536000	3.19e-01	3.35e-01
Cell junction organization	22	5.62e-01	8.06e-01	0.2700	9.24e-02	-0.083200	-2.22e-01	3.78e-02	0.080100	0.453000	0.50000	0.071300	7.59e-01	5.16e-01
Downstream TCR signaling	69	5.62e-01	8.06e-01	0.1260	-3.02e-02	-0.030200	1.10e-01	2.02e-02	0.038300	0.665000	0.66600	0.114000	7.72e-01	5.83e-01
Cell-cell junction organization	12	5.63e-01	8.06e-01	0.3920	1.80e-01	-0.029000	-3.16e-01	6.58e-02	0.127000	0.280000	0.86200	0.058300	6.93e-01	4.47e-01
Interleukin-12 family signaling	41	5.64e-01	8.06e-01	0.1780	-2.26e-02	-0.003260	1.49e-01	8.49e-04	-0.094000	0.803000	0.97100	0.098900	9.93e-01	2.98e-01
RHOA GTPase cycle	86	5.64e-01	8.06e-01	0.1130	-7.28e-02	0.057900	4.44e-02	-4.73e-02	0.001120	0.244000	0.35400	0.478000	4.49e-01	9.86e-01
Thrombin signalling through proteinase activated receptors (PARs)	17	5.68e-01	8.09e-01	0.2550	-1.70e-01	-0.161000	-8.33e-02	5.90e-02	0.006850	0.225000	0.25100	0.552000	6.74e-01	9.61e-01
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	28	5.72e-01	8.13e-01	0.2280	-9.60e-02	-0.034700	1.71e-01	1.38e-02	-0.109000	0.380000	0.75100	0.117000	9.00e-01	3.21e-01
Golgi Associated Vesicle Biogenesis	37	5.74e-01	8.13e-01	0.1790	-6.18e-02	-0.108000	-1.18e-01	3.13e-02	0.040100	0.516000	0.25600	0.215000	7.42e-01	6.73e-01
EPH-Ephrin signaling	54	5.75e-01	8.13e-01	0.1480	-4.67e-02	-0.041300	1.06e-02	-3.62e-02	-0.129000	0.554000	0.60000	0.893000	6.46e-01	1.01e-01
Toll-like Receptor Cascades	97	5.75e-01	8.13e-01	0.1140	-7.91e-02	0.058200	4.00e-02	-3.03e-02	-0.026800	0.179000	0.32300	0.497000	6.07e-01	6.49e-01
Metabolism of porphyrins	15	5.76e-01	8.13e-01	0.2720	1.03e-01	0.148000	-7.08e-02	-1.96e-02	-0.190000	0.491000	0.32200	0.635000	8.96e-01	2.03e-01
Intraflagellar transport	30	5.78e-01	8.13e-01	0.1820	-7.65e-02	-0.003750	8.73e-02	6.72e-02	0.123000	0.468000	0.97200	0.409000	5.25e-01	2.42e-01
RHOBTB1 GTPase cycle	18	5.79e-01	8.13e-01	0.2560	-6.52e-02	-0.147000	-1.07e-01	1.61e-01	0.047200	0.632000	0.28200	0.433000	2.36e-01	7.29e-01
Hedgehog ‘off’ state	74	5.80e-01	8.13e-01	0.1430	-1.35e-02	-0.048800	1.16e-02	7.25e-02	0.112000	0.842000	0.46800	0.863000	2.82e-01	9.64e-02
PI3K Cascade	18	5.81e-01	8.13e-01	0.2700	-1.85e-01	-0.025500	-5.23e-03	-7.95e-02	-0.178000	0.175000	0.85100	0.969000	5.60e-01	1.91e-01
MAPK targets/ Nuclear events mediated by MAP kinases	22	5.81e-01	8.13e-01	0.2460	-1.38e-01	0.069300	1.42e-01	4.34e-03	-0.129000	0.264000	0.57400	0.250000	9.72e-01	2.94e-01
RNA Polymerase III Chain Elongation	16	5.82e-01	8.13e-01	0.3070	-1.94e-01	-0.151000	1.08e-01	-6.60e-03	-0.149000	0.180000	0.29500	0.453000	9.64e-01	3.04e-01
RIPK1-mediated regulated necrosis	24	5.82e-01	8.13e-01	0.2530	-1.12e-01	-0.195000	2.50e-02	8.09e-02	0.079400	0.343000	0.09880	0.832000	4.93e-01	5.01e-01
Regulation of necroptotic cell death	24	5.82e-01	8.13e-01	0.2530	-1.12e-01	-0.195000	2.50e-02	8.09e-02	0.079400	0.343000	0.09880	0.832000	4.93e-01	5.01e-01
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects	15	5.82e-01	8.13e-01	0.2650	1.65e-01	0.046600	-1.27e-02	-1.58e-01	-0.126000	0.270000	0.75500	0.932000	2.91e-01	3.98e-01
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	15	5.82e-01	8.13e-01	0.2650	1.65e-01	0.046600	-1.27e-02	-1.58e-01	-0.126000	0.270000	0.75500	0.932000	2.91e-01	3.98e-01
Signaling by FGFR in disease	37	5.83e-01	8.13e-01	0.1410	-6.42e-02	0.101000	-5.94e-02	-3.88e-02	0.022800	0.500000	0.28700	0.532000	6.84e-01	8.10e-01
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	20	5.84e-01	8.13e-01	0.2270	-1.81e-01	-0.000954	5.61e-02	1.91e-02	-0.124000	0.161000	0.99400	0.664000	8.83e-01	3.38e-01
Intra-Golgi traffic	38	5.84e-01	8.13e-01	0.1690	-1.66e-01	-0.013000	3.15e-02	-5.51e-03	-0.005450	0.077600	0.89000	0.737000	9.53e-01	9.54e-01
Transport of inorganic cations/anions and amino acids/oligopeptides	37	5.84e-01	8.13e-01	0.1990	8.97e-02	0.080600	-1.47e-01	-1.96e-02	0.055400	0.346000	0.39700	0.123000	8.37e-01	5.60e-01
Glycogen metabolism	17	5.84e-01	8.13e-01	0.2480	-1.30e-01	-0.036500	-9.79e-02	1.19e-01	0.140000	0.354000	0.79500	0.485000	3.97e-01	3.19e-01
Apoptotic execution phase	32	5.86e-01	8.14e-01	0.2470	-1.87e-01	-0.057100	1.19e-01	-8.22e-02	-0.041400	0.067500	0.57700	0.244000	4.21e-01	6.85e-01
AKT phosphorylates targets in the cytosol	13	5.89e-01	8.17e-01	0.3830	-2.81e-01	-0.142000	1.72e-01	-1.28e-01	-0.045000	0.079800	0.37400	0.284000	4.23e-01	7.79e-01
Toll Like Receptor 9 (TLR9) Cascade	64	5.91e-01	8.20e-01	0.1160	-8.93e-02	0.052600	4.85e-02	2.12e-02	0.004370	0.217000	0.46700	0.503000	7.70e-01	9.52e-01
Protein ubiquitination	55	5.93e-01	8.20e-01	0.1630	-1.34e-01	-0.022000	3.14e-02	-3.41e-02	-0.077700	0.085200	0.77900	0.687000	6.62e-01	3.20e-01
Interconversion of nucleotide di- and triphosphates	21	5.93e-01	8.20e-01	0.2410	-1.00e-01	-0.045300	-2.25e-02	1.30e-01	0.170000	0.427000	0.71900	0.858000	3.04e-01	1.78e-01
ERKs are inactivated	11	5.95e-01	8.20e-01	0.2910	1.41e-01	0.099200	1.20e-01	2.01e-01	-0.007560	0.419000	0.56900	0.489000	2.49e-01	9.65e-01
TP53 Regulates Transcription of Cell Cycle Genes	40	5.95e-01	8.20e-01	0.1700	-3.32e-02	-0.075900	1.44e-01	2.20e-02	-0.024200	0.716000	0.40700	0.115000	8.10e-01	7.92e-01
Metabolism of lipids	411	5.96e-01	8.21e-01	0.0612	2.54e-02	0.050200	-2.09e-02	1.24e-02	-0.000947	0.382000	0.08460	0.473000	6.71e-01	9.74e-01
Transcriptional regulation by RUNX2	82	5.98e-01	8.23e-01	0.1320	-2.25e-02	-0.109000	2.01e-02	4.27e-02	0.054100	0.725000	0.08860	0.753000	5.05e-01	3.98e-01
PCNA-Dependent Long Patch Base Excision Repair	18	5.98e-01	8.23e-01	0.3010	-2.27e-01	-0.074200	1.08e-01	-3.94e-02	-0.143000	0.095500	0.58600	0.430000	7.73e-01	2.94e-01
Toll Like Receptor 3 (TLR3) Cascade	70	6.03e-01	8.28e-01	0.1080	-5.46e-02	0.040400	4.51e-02	6.53e-02	0.028800	0.431000	0.56000	0.515000	3.46e-01	6.77e-01
C-type lectin receptors (CLRs)	97	6.07e-01	8.32e-01	0.1010	-5.39e-02	-0.027900	6.43e-02	-1.08e-02	0.047500	0.360000	0.63600	0.275000	8.54e-01	4.21e-01
Regulation of insulin secretion	36	6.08e-01	8.32e-01	0.1960	-4.64e-02	0.056000	2.09e-02	-1.70e-01	-0.061700	0.630000	0.56100	0.828000	7.87e-02	5.22e-01
Rap1 signalling	11	6.14e-01	8.38e-01	0.4580	-1.67e-01	0.010000	2.60e-01	-1.99e-01	-0.272000	0.337000	0.95400	0.136000	2.53e-01	1.18e-01
Transcriptional regulation by small RNAs	40	6.14e-01	8.38e-01	0.1580	-8.98e-02	0.000834	1.05e-01	5.28e-02	0.055000	0.326000	0.99300	0.250000	5.64e-01	5.47e-01
Synthesis of PIPs at the plasma membrane	36	6.16e-01	8.38e-01	0.1550	4.69e-02	0.068600	-3.89e-02	1.55e-03	-0.124000	0.627000	0.47700	0.687000	9.87e-01	1.97e-01
Metal ion SLC transporters	13	6.16e-01	8.38e-01	0.3750	8.46e-02	-0.001590	-9.53e-02	2.99e-01	0.186000	0.597000	0.99200	0.552000	6.20e-02	2.45e-01
EPH-ephrin mediated repulsion of cells	24	6.16e-01	8.38e-01	0.1690	-1.25e-01	-0.049000	-9.15e-03	9.24e-02	-0.043900	0.291000	0.67800	0.938000	4.34e-01	7.10e-01
Cellular Senescence	99	6.16e-01	8.38e-01	0.0974	-5.32e-03	-0.024100	9.35e-02	-1.03e-02	0.005100	0.927000	0.67900	0.109000	8.60e-01	9.30e-01
Vpr-mediated nuclear import of PICs	30	6.18e-01	8.39e-01	0.1840	-7.92e-02	-0.012500	9.92e-02	1.03e-01	0.082500	0.453000	0.90600	0.348000	3.28e-01	4.34e-01
G1/S-Specific Transcription	24	6.23e-01	8.44e-01	0.2300	6.14e-02	0.198000	-4.54e-02	6.80e-02	0.055800	0.603000	0.09370	0.700000	5.64e-01	6.36e-01
HSF1-dependent transactivation	25	6.23e-01	8.44e-01	0.1840	1.79e-04	-0.107000	1.25e-01	7.77e-02	-0.029500	0.999000	0.35600	0.279000	5.02e-01	7.99e-01
NS1 Mediated Effects on Host Pathways	36	6.26e-01	8.45e-01	0.1690	-1.17e-01	-0.002790	1.07e-01	3.97e-02	0.041700	0.224000	0.97700	0.267000	6.80e-01	6.66e-01
ZBP1(DAI) mediated induction of type I IFNs	15	6.28e-01	8.45e-01	0.2290	-8.48e-02	0.078100	6.12e-02	1.77e-01	0.062300	0.570000	0.60100	0.682000	2.35e-01	6.76e-01
Translocation of SLC2A4 (GLUT4) to the plasma membrane	43	6.28e-01	8.45e-01	0.1320	3.01e-02	-0.012700	-5.64e-03	-3.56e-03	0.128000	0.733000	0.88600	0.949000	9.68e-01	1.47e-01
Metabolism of nitric oxide: NOS3 activation and regulation	12	6.30e-01	8.45e-01	0.3190	5.54e-02	-0.007830	1.71e-02	-2.51e-01	-0.189000	0.740000	0.96300	0.918000	1.33e-01	2.58e-01
Signaling by Non-Receptor Tyrosine Kinases	33	6.30e-01	8.45e-01	0.1720	-3.73e-02	-0.033400	7.35e-02	6.42e-02	0.133000	0.711000	0.74000	0.465000	5.24e-01	1.87e-01
Signaling by PTK6	33	6.30e-01	8.45e-01	0.1720	-3.73e-02	-0.033400	7.35e-02	6.42e-02	0.133000	0.711000	0.74000	0.465000	5.24e-01	1.87e-01
Interleukin receptor SHC signaling	15	6.31e-01	8.45e-01	0.3120	-8.86e-02	0.023400	2.30e-01	-3.58e-02	-0.187000	0.553000	0.87500	0.123000	8.11e-01	2.11e-01
Collagen biosynthesis and modifying enzymes	13	6.34e-01	8.45e-01	0.2270	6.41e-02	-0.138000	-2.17e-02	-1.66e-01	0.003540	0.689000	0.38800	0.893000	3.00e-01	9.82e-01
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	15	6.34e-01	8.45e-01	0.2330	-5.76e-02	0.106000	1.62e-01	-1.06e-01	0.047100	0.700000	0.47700	0.277000	4.76e-01	7.52e-01
Downstream signal transduction	20	6.34e-01	8.45e-01	0.2480	1.34e-01	0.120000	-2.31e-02	-1.03e-01	-0.135000	0.301000	0.35500	0.858000	4.26e-01	2.96e-01
Protein localization	113	6.34e-01	8.45e-01	0.1030	-1.97e-02	0.051000	7.43e-02	-4.46e-02	-0.013100	0.718000	0.35000	0.174000	4.14e-01	8.10e-01
MicroRNA (miRNA) biogenesis	17	6.34e-01	8.45e-01	0.3430	-1.55e-01	0.110000	1.76e-01	-1.48e-01	-0.168000	0.268000	0.43200	0.208000	2.92e-01	2.30e-01
Transport of bile salts and organic acids, metal ions and amine compounds	29	6.35e-01	8.45e-01	0.2130	9.11e-02	0.090700	-4.55e-02	1.60e-01	0.037300	0.396000	0.39800	0.672000	1.37e-01	7.28e-01
Beta-catenin phosphorylation cascade	15	6.35e-01	8.45e-01	0.2570	2.37e-01	0.028000	-7.85e-04	3.06e-02	0.090600	0.112000	0.85100	0.996000	8.37e-01	5.44e-01
Transcriptional Regulation by MECP2	28	6.37e-01	8.45e-01	0.2010	-2.35e-02	0.079900	1.78e-01	-2.42e-02	-0.035600	0.830000	0.46500	0.103000	8.25e-01	7.45e-01
RUNX3 regulates NOTCH signaling	11	6.37e-01	8.45e-01	0.2570	-1.57e-02	-0.010300	1.72e-01	1.85e-01	-0.043900	0.928000	0.95300	0.323000	2.89e-01	8.01e-01
Hedgehog ‘on’ state	61	6.37e-01	8.45e-01	0.1520	9.79e-04	-0.076100	2.59e-02	8.58e-02	0.096700	0.989000	0.30500	0.727000	2.47e-01	1.92e-01
Signaling by FGFR3	25	6.38e-01	8.45e-01	0.1620	-9.84e-02	-0.023600	-1.22e-01	3.31e-02	-0.005460	0.395000	0.83800	0.290000	7.74e-01	9.62e-01
NCAM signaling for neurite out-growth	23	6.38e-01	8.45e-01	0.2340	3.65e-02	0.036700	-1.40e-03	-1.92e-01	-0.123000	0.762000	0.76100	0.991000	1.10e-01	3.06e-01
RET signaling	22	6.40e-01	8.47e-01	0.2290	1.00e-01	0.103000	-1.32e-01	-7.99e-02	-0.090800	0.415000	0.40500	0.285000	5.17e-01	4.62e-01
NRAGE signals death through JNK	25	6.41e-01	8.47e-01	0.1790	-4.64e-02	0.143000	-5.77e-02	-7.79e-02	0.003150	0.688000	0.21500	0.618000	5.01e-01	9.78e-01
Signalling to ERKs	25	6.42e-01	8.48e-01	0.2270	5.39e-02	0.141000	-4.90e-02	-8.22e-02	-0.139000	0.641000	0.22100	0.672000	4.77e-01	2.29e-01
Interactions of Vpr with host cellular proteins	31	6.43e-01	8.48e-01	0.1760	-7.10e-02	-0.013400	1.21e-01	8.90e-02	0.058300	0.494000	0.89700	0.246000	3.92e-01	5.75e-01
activated TAK1 mediates p38 MAPK activation	12	6.48e-01	8.54e-01	0.3900	-2.38e-01	-0.099900	5.62e-02	-2.23e-01	-0.181000	0.154000	0.54900	0.736000	1.82e-01	2.78e-01
Signaling by Rho GTPases	413	6.52e-01	8.59e-01	0.0527	-3.48e-02	0.012300	3.46e-02	4.99e-03	-0.014100	0.231000	0.67100	0.234000	8.64e-01	6.27e-01
Phase II - Conjugation of compounds	42	6.55e-01	8.59e-01	0.2220	1.23e-01	0.022800	-8.53e-02	1.36e-01	0.088700	0.167000	0.79900	0.339000	1.27e-01	3.21e-01
Glutamate binding, activation of AMPA receptors and synaptic plasticity	12	6.55e-01	8.59e-01	0.2390	-1.53e-01	0.048400	4.29e-02	5.31e-02	-0.163000	0.358000	0.77100	0.797000	7.50e-01	3.28e-01
Trafficking of AMPA receptors	12	6.55e-01	8.59e-01	0.2390	-1.53e-01	0.048400	4.29e-02	5.31e-02	-0.163000	0.358000	0.77100	0.797000	7.50e-01	3.28e-01
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	13	6.56e-01	8.59e-01	0.2650	5.24e-02	0.176000	-1.61e-01	1.85e-02	-0.099500	0.744000	0.27100	0.314000	9.08e-01	5.35e-01
Signaling by EGFR	35	6.56e-01	8.59e-01	0.2350	-1.06e-01	0.017400	8.66e-02	-1.63e-01	-0.097000	0.277000	0.85900	0.376000	9.45e-02	3.21e-01
Diseases associated with glycosylation precursor biosynthesis	18	6.59e-01	8.59e-01	0.2870	8.72e-03	-0.141000	-1.49e-01	1.67e-01	0.113000	0.949000	0.30100	0.274000	2.21e-01	4.09e-01
RHOV GTPase cycle	22	6.59e-01	8.59e-01	0.2200	-9.45e-02	-0.038300	1.01e-01	-1.66e-01	-0.004030	0.443000	0.75600	0.411000	1.78e-01	9.74e-01
Interleukin-12 signaling	35	6.61e-01	8.59e-01	0.1950	-7.08e-02	-0.009520	1.47e-01	-7.87e-03	-0.105000	0.469000	0.92200	0.132000	9.36e-01	2.82e-01
Nucleotide salvage	18	6.61e-01	8.59e-01	0.2400	1.07e-01	0.093800	-1.63e-01	-4.22e-02	-0.094800	0.432000	0.49100	0.230000	7.57e-01	4.86e-01
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	14	6.62e-01	8.59e-01	0.2730	5.51e-02	0.050800	-1.13e-01	-1.53e-01	-0.181000	0.721000	0.74200	0.466000	3.22e-01	2.41e-01
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	19	6.63e-01	8.59e-01	0.2320	1.91e-02	0.207000	2.43e-02	-9.96e-02	-0.011500	0.885000	0.11900	0.854000	4.52e-01	9.31e-01
ADP signalling through P2Y purinoceptor 12	10	6.64e-01	8.59e-01	0.2970	2.56e-02	0.181000	1.25e-01	1.38e-01	0.142000	0.889000	0.32200	0.493000	4.50e-01	4.37e-01
Signaling by Hedgehog	97	6.66e-01	8.59e-01	0.1030	-2.55e-02	0.008180	-3.83e-02	4.82e-02	0.078800	0.665000	0.89000	0.516000	4.14e-01	1.81e-01
Antiviral mechanism by IFN-stimulated genes	73	6.66e-01	8.59e-01	0.1170	-7.83e-02	-0.037000	5.93e-02	5.19e-02	0.004920	0.249000	0.58600	0.382000	4.44e-01	9.42e-01
Diseases of glycosylation	67	6.66e-01	8.59e-01	0.1050	1.96e-02	-0.041300	-8.47e-02	-2.79e-03	-0.041700	0.782000	0.56000	0.231000	9.69e-01	5.56e-01
FLT3 Signaling	32	6.67e-01	8.59e-01	0.1740	2.98e-02	0.057800	1.06e-01	-1.16e-01	-0.039800	0.770000	0.57200	0.302000	2.56e-01	6.97e-01
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	23	6.68e-01	8.59e-01	0.2080	-3.36e-02	-0.196000	-7.82e-03	-3.88e-02	-0.045100	0.780000	0.10400	0.948000	7.48e-01	7.08e-01
Transcription of E2F targets under negative control by DREAM complex	17	6.68e-01	8.59e-01	0.2110	-5.26e-02	0.145000	-3.34e-02	9.54e-02	0.102000	0.707000	0.30100	0.812000	4.96e-01	4.68e-01
Regulation of RAS by GAPs	55	6.68e-01	8.59e-01	0.1380	-1.37e-02	-0.050000	6.15e-02	9.71e-02	0.057100	0.860000	0.52200	0.431000	2.14e-01	4.64e-01
N-Glycan antennae elongation	11	6.69e-01	8.59e-01	0.3610	2.00e-01	0.189000	-1.98e-01	7.12e-03	0.125000	0.252000	0.27800	0.256000	9.67e-01	4.73e-01
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	61	6.69e-01	8.59e-01	0.1320	-1.05e-01	0.038000	6.43e-02	-1.13e-02	-0.027000	0.157000	0.60800	0.386000	8.79e-01	7.16e-01
Transport of Ribonucleoproteins into the Host Nucleus	28	6.71e-01	8.60e-01	0.1760	-1.01e-01	-0.010500	9.55e-02	5.56e-02	0.092000	0.356000	0.92300	0.382000	6.11e-01	4.00e-01
Mitochondrial Fatty Acid Beta-Oxidation	24	6.71e-01	8.60e-01	0.2690	1.25e-01	0.043300	-1.43e-01	7.31e-02	0.171000	0.290000	0.71400	0.224000	5.35e-01	1.48e-01
Cytochrome P450 - arranged by substrate type	14	6.73e-01	8.61e-01	0.3110	4.49e-02	0.108000	2.04e-02	-2.32e-01	-0.169000	0.771000	0.48400	0.895000	1.33e-01	2.73e-01
Class B/2 (Secretin family receptors)	25	6.76e-01	8.64e-01	0.2040	1.17e-01	0.120000	-7.03e-02	-9.25e-02	-0.003620	0.311000	0.29800	0.543000	4.24e-01	9.75e-01
VxPx cargo-targeting to cilium	15	6.76e-01	8.64e-01	0.3580	1.32e-01	0.054000	-2.16e-01	1.46e-01	0.200000	0.378000	0.71800	0.147000	3.29e-01	1.80e-01
Signaling by NTRK1 (TRKA)	79	6.80e-01	8.68e-01	0.1460	-2.76e-02	0.059100	8.17e-02	-7.78e-02	-0.065600	0.672000	0.36500	0.210000	2.33e-01	3.14e-01
Glucagon-type ligand receptors	11	6.82e-01	8.68e-01	0.3000	3.61e-03	0.280000	1.03e-01	-1.76e-02	-0.028600	0.983000	0.10800	0.554000	9.19e-01	8.70e-01
Synthesis of glycosylphosphatidylinositol (GPI)	14	6.82e-01	8.68e-01	0.2780	-1.49e-02	-0.137000	3.93e-02	-1.89e-01	-0.146000	0.923000	0.37400	0.799000	2.22e-01	3.46e-01
Class I MHC mediated antigen processing & presentation	267	6.83e-01	8.68e-01	0.0618	4.52e-02	0.007030	1.15e-02	2.30e-02	0.032700	0.207000	0.84400	0.749000	5.20e-01	3.62e-01
PERK regulates gene expression	25	6.83e-01	8.68e-01	0.2340	-1.59e-01	-0.065200	1.58e-01	-1.26e-02	-0.009420	0.168000	0.57300	0.171000	9.13e-01	9.35e-01
PRC2 methylates histones and DNA	11	6.88e-01	8.73e-01	0.2050	-6.59e-02	0.022000	-2.63e-02	-1.29e-01	0.141000	0.705000	0.90000	0.880000	4.58e-01	4.18e-01
CD209 (DC-SIGN) signaling	15	6.92e-01	8.77e-01	0.2900	1.22e-01	0.208000	-1.51e-01	4.21e-03	0.052000	0.414000	0.16300	0.310000	9.77e-01	7.27e-01
Interleukin-6 family signaling	13	6.94e-01	8.77e-01	0.3150	-4.55e-02	0.032400	1.39e-02	-1.57e-01	-0.267000	0.777000	0.84000	0.931000	3.27e-01	9.62e-02
Regulation of actin dynamics for phagocytic cup formation	43	6.94e-01	8.77e-01	0.1540	-7.43e-03	-0.081400	8.04e-02	-5.30e-02	-0.088000	0.933000	0.35600	0.362000	5.48e-01	3.19e-01
Deposition of new CENPA-containing nucleosomes at the centromere	20	6.96e-01	8.77e-01	0.2020	-6.25e-02	-0.141000	-9.48e-02	8.79e-02	-0.005940	0.629000	0.27400	0.463000	4.96e-01	9.63e-01
Nucleosome assembly	20	6.96e-01	8.77e-01	0.2020	-6.25e-02	-0.141000	-9.48e-02	8.79e-02	-0.005940	0.629000	0.27400	0.463000	4.96e-01	9.63e-01
RUNX3 regulates p14-ARF	10	6.98e-01	8.77e-01	0.3080	1.29e-01	0.142000	-2.18e-01	1.57e-02	-0.101000	0.481000	0.43800	0.233000	9.32e-01	5.81e-01
Metabolic disorders of biological oxidation enzymes	14	6.98e-01	8.77e-01	0.2030	9.58e-02	-0.075900	-9.33e-02	9.76e-02	-0.088700	0.535000	0.62300	0.546000	5.27e-01	5.66e-01
Disorders of Developmental Biology	10	7.02e-01	8.77e-01	0.3410	1.45e-01	0.195000	-6.75e-02	-1.60e-01	-0.163000	0.427000	0.28500	0.712000	3.81e-01	3.72e-01
Disorders of Nervous System Development	10	7.02e-01	8.77e-01	0.3410	1.45e-01	0.195000	-6.75e-02	-1.60e-01	-0.163000	0.427000	0.28500	0.712000	3.81e-01	3.72e-01
Loss of function of MECP2 in Rett syndrome	10	7.02e-01	8.77e-01	0.3410	1.45e-01	0.195000	-6.75e-02	-1.60e-01	-0.163000	0.427000	0.28500	0.712000	3.81e-01	3.72e-01
Pervasive developmental disorders	10	7.02e-01	8.77e-01	0.3410	1.45e-01	0.195000	-6.75e-02	-1.60e-01	-0.163000	0.427000	0.28500	0.712000	3.81e-01	3.72e-01
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	65	7.03e-01	8.77e-01	0.1250	-7.42e-02	0.061000	1.88e-03	-6.65e-02	-0.044000	0.302000	0.39600	0.979000	3.55e-01	5.41e-01
Toll Like Receptor 2 (TLR2) Cascade	65	7.03e-01	8.77e-01	0.1250	-7.42e-02	0.061000	1.88e-03	-6.65e-02	-0.044000	0.302000	0.39600	0.979000	3.55e-01	5.41e-01
Toll Like Receptor TLR1:TLR2 Cascade	65	7.03e-01	8.77e-01	0.1250	-7.42e-02	0.061000	1.88e-03	-6.65e-02	-0.044000	0.302000	0.39600	0.979000	3.55e-01	5.41e-01
Toll Like Receptor TLR6:TLR2 Cascade	65	7.03e-01	8.77e-01	0.1250	-7.42e-02	0.061000	1.88e-03	-6.65e-02	-0.044000	0.302000	0.39600	0.979000	3.55e-01	5.41e-01
MyD88-independent TLR4 cascade	70	7.04e-01	8.77e-01	0.0961	-6.51e-02	0.035400	3.86e-02	4.57e-02	0.013100	0.347000	0.60900	0.577000	5.09e-01	8.50e-01
TRIF(TICAM1)-mediated TLR4 signaling	70	7.04e-01	8.77e-01	0.0961	-6.51e-02	0.035400	3.86e-02	4.57e-02	0.013100	0.347000	0.60900	0.577000	5.09e-01	8.50e-01
VEGFR2 mediated vascular permeability	21	7.07e-01	8.80e-01	0.1630	-5.43e-02	0.031000	-1.09e-01	-9.07e-02	0.053100	0.667000	0.80600	0.390000	4.72e-01	6.74e-01
RHOBTB GTPase Cycle	28	7.08e-01	8.80e-01	0.2000	-1.19e-01	-0.156000	1.15e-02	3.67e-02	0.002710	0.277000	0.15300	0.916000	7.37e-01	9.80e-01
Response of Mtb to phagocytosis	20	7.09e-01	8.80e-01	0.2260	-2.17e-02	-0.131000	-3.92e-02	1.69e-01	0.056600	0.867000	0.30900	0.761000	1.90e-01	6.62e-01
Sensory processing of sound	24	7.11e-01	8.81e-01	0.2020	1.90e-01	0.020500	-6.03e-02	1.40e-02	0.018000	0.107000	0.86200	0.609000	9.06e-01	8.79e-01
Sensory processing of sound by inner hair cells of the cochlea	24	7.11e-01	8.81e-01	0.2020	1.90e-01	0.020500	-6.03e-02	1.40e-02	0.018000	0.107000	0.86200	0.609000	9.06e-01	8.79e-01
HDMs demethylate histones	15	7.13e-01	8.82e-01	0.3020	-1.92e-01	-0.047100	1.47e-01	-1.71e-01	-0.039200	0.197000	0.75200	0.324000	2.53e-01	7.93e-01
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	13	7.16e-01	8.85e-01	0.2990	3.10e-02	-0.024500	-3.16e-02	1.32e-01	0.263000	0.846000	0.87800	0.844000	4.10e-01	1.00e-01
Signaling by Ligand-Responsive EGFR Variants in Cancer	13	7.16e-01	8.85e-01	0.2990	3.10e-02	-0.024500	-3.16e-02	1.32e-01	0.263000	0.846000	0.87800	0.844000	4.10e-01	1.00e-01
G2/M DNA damage checkpoint	51	7.19e-01	8.86e-01	0.1570	-1.31e-01	-0.022900	7.65e-02	-2.11e-02	-0.024400	0.106000	0.77700	0.345000	7.94e-01	7.63e-01
Signaling by FGFR4	24	7.19e-01	8.86e-01	0.1660	-8.16e-02	-0.054800	-1.24e-01	4.82e-02	0.014500	0.490000	0.64200	0.295000	6.83e-01	9.02e-01
Amino acids regulate mTORC1	35	7.20e-01	8.86e-01	0.1180	-8.84e-02	-0.008230	-3.95e-03	5.80e-02	-0.052400	0.366000	0.93300	0.968000	5.53e-01	5.92e-01
Fc epsilon receptor (FCERI) signaling	103	7.22e-01	8.87e-01	0.1030	-5.41e-02	-0.009600	8.70e-02	-1.08e-02	0.000392	0.345000	0.86700	0.128000	8.50e-01	9.95e-01
Caspase activation via Death Receptors in the presence of ligand	10	7.22e-01	8.87e-01	0.3140	-1.73e-01	-0.127000	1.77e-01	1.16e-01	0.089200	0.344000	0.48800	0.333000	5.26e-01	6.25e-01
Diseases of DNA repair	10	7.29e-01	8.93e-01	0.2700	5.90e-03	0.164000	1.37e-01	1.16e-01	0.118000	0.974000	0.37000	0.455000	5.24e-01	5.18e-01
RHOD GTPase cycle	33	7.29e-01	8.93e-01	0.1610	2.97e-02	0.063800	6.21e-02	1.13e-01	0.065100	0.768000	0.52600	0.538000	2.62e-01	5.18e-01
DNA strand elongation	27	7.30e-01	8.93e-01	0.1850	-1.10e-01	-0.053100	1.21e-01	5.64e-02	-0.039000	0.321000	0.63300	0.277000	6.12e-01	7.26e-01
ATF4 activates genes in response to endoplasmic reticulum stress	22	7.31e-01	8.93e-01	0.2540	-1.41e-01	-0.093300	1.72e-01	-6.83e-02	-0.036900	0.252000	0.44900	0.162000	5.80e-01	7.65e-01
Signaling by BMP	13	7.32e-01	8.94e-01	0.2690	1.69e-01	0.133000	3.92e-03	-1.22e-01	-0.105000	0.292000	0.40600	0.980000	4.48e-01	5.11e-01
EGR2 and SOX10-mediated initiation of Schwann cell myelination	12	7.32e-01	8.94e-01	0.2850	-9.06e-03	-0.140000	1.29e-01	-1.57e-01	-0.143000	0.957000	0.40100	0.440000	3.47e-01	3.92e-01
Phosphorylation of the APC/C	15	7.36e-01	8.94e-01	0.2480	2.09e-01	-0.020400	-8.10e-02	1.04e-01	0.004010	0.160000	0.89200	0.587000	4.84e-01	9.79e-01
G0 and Early G1	24	7.36e-01	8.94e-01	0.1660	3.90e-03	0.109000	5.50e-02	4.13e-02	0.105000	0.974000	0.35500	0.641000	7.26e-01	3.75e-01
RAB GEFs exchange GTP for GDP on RABs	56	7.36e-01	8.94e-01	0.1020	-6.52e-02	-0.014000	-7.34e-02	-2.39e-03	0.024300	0.399000	0.85600	0.343000	9.75e-01	7.53e-01
GABA receptor activation	16	7.37e-01	8.94e-01	0.1970	-1.26e-02	0.168000	-5.40e-02	-5.03e-02	0.070500	0.930000	0.24500	0.709000	7.28e-01	6.25e-01
Apoptotic cleavage of cellular proteins	24	7.38e-01	8.94e-01	0.2560	-1.58e-01	0.005220	1.52e-01	-1.09e-01	-0.075300	0.181000	0.96500	0.199000	3.54e-01	5.23e-01
Signaling by Rho GTPases, Miro GTPases and RHOBTB3	425	7.39e-01	8.94e-01	0.0477	-3.08e-02	0.015100	3.18e-02	1.16e-03	-0.009360	0.283000	0.59900	0.267000	9.68e-01	7.44e-01
G-protein beta:gamma signalling	18	7.39e-01	8.94e-01	0.2780	-8.03e-02	0.140000	8.80e-02	-1.68e-01	-0.123000	0.555000	0.30200	0.518000	2.16e-01	3.67e-01
Infection with Mycobacterium tuberculosis	22	7.40e-01	8.94e-01	0.1970	-4.28e-02	-0.145000	-5.89e-02	1.10e-01	0.019800	0.728000	0.23900	0.633000	3.71e-01	8.72e-01
HSF1 activation	21	7.41e-01	8.94e-01	0.2340	-2.35e-02	-0.127000	2.40e-02	1.54e-01	0.117000	0.852000	0.31400	0.849000	2.23e-01	3.54e-01
Cell-Cell communication	44	7.42e-01	8.94e-01	0.1180	-2.74e-03	-0.025300	-7.91e-02	-8.34e-02	0.008280	0.975000	0.77200	0.364000	3.39e-01	9.24e-01
MyD88 dependent cascade initiated on endosome	62	7.43e-01	8.94e-01	0.1110	-8.78e-02	0.042700	4.84e-02	2.99e-03	-0.018300	0.232000	0.56100	0.511000	9.68e-01	8.04e-01
Toll Like Receptor 7/8 (TLR7/8) Cascade	62	7.43e-01	8.94e-01	0.1110	-8.78e-02	0.042700	4.84e-02	2.99e-03	-0.018300	0.232000	0.56100	0.511000	9.68e-01	8.04e-01
TRAF3-dependent IRF activation pathway	13	7.44e-01	8.94e-01	0.3510	1.53e-01	0.112000	-1.05e-01	1.85e-01	0.205000	0.340000	0.48600	0.511000	2.48e-01	2.01e-01
FCERI mediated MAPK activation	22	7.46e-01	8.94e-01	0.1970	-5.89e-02	0.167000	5.93e-02	-5.26e-02	-0.035100	0.633000	0.17500	0.630000	6.69e-01	7.76e-01
TRAF6 mediated IRF7 activation	15	7.48e-01	8.94e-01	0.2710	2.57e-02	0.069600	-1.86e-02	1.96e-01	0.171000	0.863000	0.64100	0.901000	1.88e-01	2.52e-01
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	20	7.50e-01	8.94e-01	0.2220	-5.85e-02	0.052900	1.97e-01	-5.79e-02	-0.034700	0.651000	0.68200	0.128000	6.54e-01	7.88e-01
Oncogene Induced Senescence	27	7.51e-01	8.94e-01	0.2130	-6.92e-03	-0.068200	-2.57e-02	1.09e-01	0.167000	0.950000	0.54000	0.818000	3.29e-01	1.33e-01
FLT3 signaling in disease	24	7.51e-01	8.94e-01	0.2180	-1.23e-01	-0.019600	-1.81e-02	-1.21e-01	-0.130000	0.298000	0.86800	0.878000	3.05e-01	2.71e-01
RNA Polymerase I Promoter Clearance	42	7.51e-01	8.94e-01	0.1030	4.28e-02	-0.042900	7.18e-02	-2.16e-02	0.037600	0.632000	0.63100	0.421000	8.09e-01	6.74e-01
RNA Polymerase I Transcription	42	7.51e-01	8.94e-01	0.1030	4.28e-02	-0.042900	7.18e-02	-2.16e-02	0.037600	0.632000	0.63100	0.421000	8.09e-01	6.74e-01
MyD88 cascade initiated on plasma membrane	60	7.51e-01	8.94e-01	0.1190	-8.40e-02	0.061600	3.61e-02	-2.75e-02	-0.034300	0.261000	0.41000	0.629000	7.13e-01	6.46e-01
Toll Like Receptor 10 (TLR10) Cascade	60	7.51e-01	8.94e-01	0.1190	-8.40e-02	0.061600	3.61e-02	-2.75e-02	-0.034300	0.261000	0.41000	0.629000	7.13e-01	6.46e-01
Toll Like Receptor 5 (TLR5) Cascade	60	7.51e-01	8.94e-01	0.1190	-8.40e-02	0.061600	3.61e-02	-2.75e-02	-0.034300	0.261000	0.41000	0.629000	7.13e-01	6.46e-01
DDX58/IFIH1-mediated induction of interferon-alpha/beta	56	7.53e-01	8.95e-01	0.1450	2.48e-02	0.019400	2.05e-03	1.08e-01	0.090500	0.749000	0.80200	0.979000	1.61e-01	2.42e-01
Activation of kainate receptors upon glutamate binding	14	7.53e-01	8.95e-01	0.2620	1.48e-01	0.183000	-1.70e-02	-8.03e-03	-0.114000	0.339000	0.23600	0.913000	9.59e-01	4.59e-01
Signaling by TGFB family members	71	7.53e-01	8.95e-01	0.1310	-5.77e-02	0.038000	8.21e-03	-6.29e-02	-0.090900	0.402000	0.58100	0.905000	3.60e-01	1.86e-01
Role of LAT2/NTAL/LAB on calcium mobilization	10	7.54e-01	8.95e-01	0.4190	-1.55e-01	0.082400	2.00e-01	-2.31e-01	-0.226000	0.397000	0.65200	0.274000	2.07e-01	2.15e-01
Transferrin endocytosis and recycling	18	7.59e-01	8.99e-01	0.2390	7.19e-02	0.175000	-1.13e-01	8.01e-02	0.047600	0.598000	0.20000	0.405000	5.56e-01	7.27e-01
RHOU GTPase cycle	24	7.66e-01	9.05e-01	0.2000	-1.33e-01	0.036600	1.12e-01	-9.17e-02	-0.008570	0.261000	0.75600	0.344000	4.37e-01	9.42e-01
PI Metabolism	59	7.66e-01	9.05e-01	0.0848	-1.80e-02	0.035300	-2.85e-02	2.45e-02	-0.064900	0.812000	0.64000	0.705000	7.45e-01	3.89e-01
Signaling by EGFR in Cancer	15	7.67e-01	9.05e-01	0.2270	-1.53e-03	-0.029900	-3.45e-02	5.22e-02	0.216000	0.992000	0.84100	0.817000	7.26e-01	1.48e-01
Signaling by NTRKs	86	7.72e-01	9.09e-01	0.1340	-2.71e-02	0.038700	6.62e-02	-6.77e-02	-0.082300	0.664000	0.53600	0.290000	2.79e-01	1.88e-01
Zinc transporters	10	7.73e-01	9.09e-01	0.3680	6.11e-02	-0.063700	-1.07e-01	2.81e-01	0.194000	0.738000	0.72700	0.558000	1.25e-01	2.88e-01
RNA Polymerase III Transcription Termination	20	7.76e-01	9.09e-01	0.2170	-1.23e-01	-0.106000	7.36e-02	-8.76e-03	-0.124000	0.341000	0.41400	0.569000	9.46e-01	3.37e-01
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	41	7.76e-01	9.09e-01	0.1170	-2.57e-02	-0.000472	6.48e-02	9.45e-02	0.000263	0.776000	0.99600	0.473000	2.96e-01	9.98e-01
Constitutive Signaling by NOTCH1 PEST Domain Mutants	41	7.76e-01	9.09e-01	0.1170	-2.57e-02	-0.000472	6.48e-02	9.45e-02	0.000263	0.776000	0.99600	0.473000	2.96e-01	9.98e-01
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	41	7.76e-01	9.09e-01	0.1170	-2.57e-02	-0.000472	6.48e-02	9.45e-02	0.000263	0.776000	0.99600	0.473000	2.96e-01	9.98e-01
Signaling by NOTCH1 PEST Domain Mutants in Cancer	41	7.76e-01	9.09e-01	0.1170	-2.57e-02	-0.000472	6.48e-02	9.45e-02	0.000263	0.776000	0.99600	0.473000	2.96e-01	9.98e-01
Signaling by NOTCH1 in Cancer	41	7.76e-01	9.09e-01	0.1170	-2.57e-02	-0.000472	6.48e-02	9.45e-02	0.000263	0.776000	0.99600	0.473000	2.96e-01	9.98e-01
Defects in vitamin and cofactor metabolism	16	7.77e-01	9.09e-01	0.1810	9.54e-03	0.053600	5.78e-02	3.91e-02	-0.158000	0.947000	0.71100	0.689000	7.87e-01	2.74e-01
Signaling by FGFR1	27	7.78e-01	9.09e-01	0.1320	-8.38e-02	-0.001760	-8.86e-02	-8.23e-03	-0.049700	0.451000	0.98700	0.426000	9.41e-01	6.55e-01
Synthesis of substrates in N-glycan biosythesis	43	7.80e-01	9.11e-01	0.1130	2.82e-02	-0.057200	1.99e-02	9.14e-02	-0.007510	0.749000	0.51700	0.822000	3.00e-01	9.32e-01
Amyloid fiber formation	27	7.81e-01	9.11e-01	0.1540	-2.98e-02	-0.032500	-1.42e-01	3.49e-02	0.019400	0.789000	0.77000	0.201000	7.54e-01	8.61e-01
Glycolysis	54	7.83e-01	9.12e-01	0.1180	-6.36e-03	0.035600	3.12e-02	7.32e-02	0.078600	0.936000	0.65100	0.692000	3.53e-01	3.19e-01
RHOF GTPase cycle	23	7.85e-01	9.12e-01	0.1660	5.03e-03	0.089500	1.02e-01	7.73e-02	0.056200	0.967000	0.45800	0.398000	5.21e-01	6.41e-01
Suppression of phagosomal maturation	12	7.85e-01	9.12e-01	0.3210	2.68e-02	-0.104000	-2.50e-02	2.25e-01	0.202000	0.872000	0.53500	0.881000	1.78e-01	2.27e-01
Activation of GABAB receptors	15	7.85e-01	9.12e-01	0.1760	-6.44e-02	0.128000	-4.51e-02	-5.91e-03	0.091400	0.666000	0.39100	0.763000	9.68e-01	5.40e-01
GABA B receptor activation	15	7.85e-01	9.12e-01	0.1760	-6.44e-02	0.128000	-4.51e-02	-5.91e-03	0.091400	0.666000	0.39100	0.763000	9.68e-01	5.40e-01
Signaling by FGFR	50	7.87e-01	9.12e-01	0.0970	-7.97e-02	0.022100	-3.53e-02	-5.81e-03	-0.035900	0.330000	0.78700	0.666000	9.43e-01	6.61e-01
B-WICH complex positively regulates rRNA expression	25	7.90e-01	9.12e-01	0.1570	3.81e-02	0.077700	7.08e-02	4.93e-02	0.098700	0.742000	0.50100	0.541000	6.70e-01	3.93e-01
G beta:gamma signalling through CDC42	10	7.90e-01	9.12e-01	0.2930	-2.71e-02	0.222000	1.69e-01	-5.95e-02	-0.065100	0.882000	0.22500	0.356000	7.45e-01	7.22e-01
Energy dependent regulation of mTOR by LKB1-AMPK	21	7.91e-01	9.12e-01	0.2520	-7.96e-02	0.023300	4.16e-02	-1.43e-01	-0.186000	0.528000	0.85400	0.741000	2.56e-01	1.41e-01
S33 mutants of beta-catenin aren’t phosphorylated	13	7.96e-01	9.12e-01	0.2410	2.13e-01	0.002200	2.26e-03	1.03e-01	0.048600	0.184000	0.98900	0.989000	5.21e-01	7.62e-01
S37 mutants of beta-catenin aren’t phosphorylated	13	7.96e-01	9.12e-01	0.2410	2.13e-01	0.002200	2.26e-03	1.03e-01	0.048600	0.184000	0.98900	0.989000	5.21e-01	7.62e-01
S45 mutants of beta-catenin aren’t phosphorylated	13	7.96e-01	9.12e-01	0.2410	2.13e-01	0.002200	2.26e-03	1.03e-01	0.048600	0.184000	0.98900	0.989000	5.21e-01	7.62e-01
Signaling by CTNNB1 phospho-site mutants	13	7.96e-01	9.12e-01	0.2410	2.13e-01	0.002200	2.26e-03	1.03e-01	0.048600	0.184000	0.98900	0.989000	5.21e-01	7.62e-01
Signaling by GSK3beta mutants	13	7.96e-01	9.12e-01	0.2410	2.13e-01	0.002200	2.26e-03	1.03e-01	0.048600	0.184000	0.98900	0.989000	5.21e-01	7.62e-01
T41 mutants of beta-catenin aren’t phosphorylated	13	7.96e-01	9.12e-01	0.2410	2.13e-01	0.002200	2.26e-03	1.03e-01	0.048600	0.184000	0.98900	0.989000	5.21e-01	7.62e-01
SLC transporter disorders	46	7.97e-01	9.12e-01	0.1160	-3.20e-02	0.022100	5.35e-02	5.94e-02	0.075000	0.708000	0.79500	0.531000	4.87e-01	3.80e-01
Base-Excision Repair, AP Site Formation	15	7.98e-01	9.12e-01	0.2010	-4.92e-02	-0.041200	-4.62e-02	-5.34e-02	-0.177000	0.742000	0.78200	0.757000	7.21e-01	2.36e-01
RHO GTPases Activate NADPH Oxidases	14	7.98e-01	9.12e-01	0.2400	-8.81e-02	0.118000	-1.76e-02	-8.51e-02	-0.169000	0.568000	0.44500	0.909000	5.82e-01	2.74e-01
EGFR downregulation	20	7.99e-01	9.12e-01	0.1830	-1.39e-01	-0.087400	-2.94e-02	-2.20e-02	0.070800	0.281000	0.49900	0.820000	8.65e-01	5.84e-01
Role of phospholipids in phagocytosis	16	7.99e-01	9.12e-01	0.2750	-1.13e-01	-0.086900	1.18e-01	-1.83e-01	-0.087900	0.434000	0.54700	0.413000	2.05e-01	5.43e-01
FCGR3A-mediated phagocytosis	41	8.00e-01	9.12e-01	0.1860	-8.51e-02	-0.061600	9.28e-02	-7.35e-02	-0.098100	0.346000	0.49600	0.305000	4.16e-01	2.78e-01
Leishmania phagocytosis	41	8.00e-01	9.12e-01	0.1860	-8.51e-02	-0.061600	9.28e-02	-7.35e-02	-0.098100	0.346000	0.49600	0.305000	4.16e-01	2.78e-01
Parasite infection	41	8.00e-01	9.12e-01	0.1860	-8.51e-02	-0.061600	9.28e-02	-7.35e-02	-0.098100	0.346000	0.49600	0.305000	4.16e-01	2.78e-01
trans-Golgi Network Vesicle Budding	50	8.05e-01	9.15e-01	0.1180	-6.98e-02	-0.072200	-5.37e-02	-3.38e-03	0.029500	0.394000	0.37800	0.512000	9.67e-01	7.18e-01
MAP2K and MAPK activation	22	8.06e-01	9.15e-01	0.2180	-3.63e-02	0.119000	6.23e-02	-7.07e-02	-0.152000	0.768000	0.33300	0.613000	5.66e-01	2.17e-01
Signaling by high-kinase activity BRAF mutants	22	8.06e-01	9.15e-01	0.2180	-3.63e-02	0.119000	6.23e-02	-7.07e-02	-0.152000	0.768000	0.33300	0.613000	5.66e-01	2.17e-01
Regulation of MECP2 expression and activity	20	8.07e-01	9.15e-01	0.1880	7.40e-02	0.155000	7.13e-02	-2.40e-02	0.010800	0.567000	0.23000	0.581000	8.53e-01	9.33e-01
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	32	8.09e-01	9.15e-01	0.1260	7.86e-02	0.009300	3.94e-02	1.34e-02	0.088200	0.442000	0.92800	0.700000	8.96e-01	3.88e-01
Post-chaperonin tubulin folding pathway	12	8.10e-01	9.15e-01	0.2030	2.61e-02	0.087000	3.56e-02	3.74e-02	-0.174000	0.876000	0.60200	0.831000	8.23e-01	2.97e-01
Interleukin-6 signaling	10	8.11e-01	9.15e-01	0.2570	4.28e-02	0.035100	1.27e-01	-3.43e-02	-0.214000	0.815000	0.84800	0.488000	8.51e-01	2.40e-01
Selective autophagy	50	8.13e-01	9.15e-01	0.1280	-1.44e-02	-0.072700	2.39e-02	-6.94e-02	-0.073700	0.860000	0.37500	0.771000	3.96e-01	3.68e-01
ISG15 antiviral mechanism	67	8.13e-01	9.15e-01	0.0964	-7.48e-02	-0.021900	2.55e-02	4.60e-02	0.021000	0.290000	0.75700	0.718000	5.16e-01	7.67e-01
Post-translational modification: synthesis of GPI-anchored proteins	30	8.13e-01	9.15e-01	0.1600	1.45e-02	-0.131000	-5.45e-02	7.16e-03	0.072700	0.891000	0.21400	0.606000	9.46e-01	4.91e-01
Striated Muscle Contraction	10	8.14e-01	9.15e-01	0.2740	3.92e-02	0.201000	-1.04e-01	-1.37e-01	-0.061200	0.830000	0.27200	0.568000	4.52e-01	7.37e-01
Ca2+ pathway	34	8.16e-01	9.15e-01	0.1250	-1.14e-02	0.108000	4.87e-02	-8.64e-03	0.038200	0.908000	0.27600	0.624000	9.31e-01	7.00e-01
Keratan sulfate biosynthesis	14	8.16e-01	9.15e-01	0.2010	-9.32e-03	0.139000	-1.44e-01	3.71e-03	-0.000493	0.952000	0.36800	0.350000	9.81e-01	9.97e-01
HIV elongation arrest and recovery	21	8.18e-01	9.15e-01	0.1620	-1.32e-01	0.076000	1.48e-02	-2.18e-02	-0.049500	0.294000	0.54700	0.906000	8.63e-01	6.94e-01
Pausing and recovery of HIV elongation	21	8.18e-01	9.15e-01	0.1620	-1.32e-01	0.076000	1.48e-02	-2.18e-02	-0.049500	0.294000	0.54700	0.906000	8.63e-01	6.94e-01
Pausing and recovery of Tat-mediated HIV elongation	21	8.18e-01	9.15e-01	0.1620	-1.32e-01	0.076000	1.48e-02	-2.18e-02	-0.049500	0.294000	0.54700	0.906000	8.63e-01	6.94e-01
Tat-mediated HIV elongation arrest and recovery	21	8.18e-01	9.15e-01	0.1620	-1.32e-01	0.076000	1.48e-02	-2.18e-02	-0.049500	0.294000	0.54700	0.906000	8.63e-01	6.94e-01
Sensory processing of sound by outer hair cells of the cochlea	15	8.18e-01	9.15e-01	0.1710	6.09e-02	-0.141000	2.10e-02	-5.09e-02	0.051200	0.683000	0.34500	0.888000	7.33e-01	7.31e-01
G-protein activation	10	8.18e-01	9.15e-01	0.2300	-1.67e-01	0.020500	1.09e-01	2.25e-02	0.112000	0.361000	0.91100	0.552000	9.02e-01	5.40e-01
RIP-mediated NFkB activation via ZBP1	12	8.18e-01	9.15e-01	0.2310	-1.01e-01	-0.030800	1.13e-01	1.49e-01	0.085700	0.544000	0.85300	0.499000	3.73e-01	6.07e-01
Signaling by Nuclear Receptors	142	8.25e-01	9.21e-01	0.0670	-6.80e-03	0.050000	2.87e-02	-3.33e-02	-0.000329	0.889000	0.30500	0.556000	4.95e-01	9.95e-01
ERK/MAPK targets	16	8.26e-01	9.22e-01	0.1800	-6.41e-02	0.072900	1.06e-01	6.31e-02	-0.088500	0.658000	0.61400	0.464000	6.62e-01	5.40e-01
Interleukin-1 family signaling	92	8.27e-01	9.22e-01	0.0849	-6.30e-02	-0.039000	1.30e-02	-3.90e-03	0.039200	0.298000	0.51900	0.830000	9.49e-01	5.17e-01
MAP kinase activation	46	8.28e-01	9.22e-01	0.1160	-9.94e-02	0.014500	5.63e-02	-7.46e-03	0.015400	0.244000	0.86500	0.509000	9.30e-01	8.57e-01
Platelet sensitization by LDL	13	8.30e-01	9.23e-01	0.1890	1.42e-01	0.040400	7.57e-02	3.24e-02	-0.084700	0.376000	0.80100	0.637000	8.40e-01	5.97e-01
TNFR1-induced NFkappaB signaling pathway	19	8.32e-01	9.23e-01	0.1800	-1.10e-01	-0.080500	7.40e-02	5.37e-02	-0.073800	0.407000	0.54400	0.577000	6.86e-01	5.78e-01
Purine ribonucleoside monophosphate biosynthesis	10	8.32e-01	9.23e-01	0.2200	2.07e-01	0.041200	4.92e-02	-7.61e-03	0.039900	0.257000	0.82100	0.788000	9.67e-01	8.27e-01
Signal amplification	17	8.33e-01	9.23e-01	0.2040	-1.92e-01	-0.023000	5.23e-02	-1.32e-02	-0.040100	0.171000	0.87000	0.709000	9.25e-01	7.75e-01
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	25	8.34e-01	9.23e-01	0.1280	-5.05e-02	0.092400	-7.03e-02	1.45e-02	-0.004400	0.663000	0.42400	0.543000	9.00e-01	9.70e-01
Negative regulation of MET activity	16	8.34e-01	9.23e-01	0.1830	-1.42e-01	-0.043300	-1.42e-02	3.45e-02	0.101000	0.327000	0.76400	0.922000	8.11e-01	4.83e-01
Keratan sulfate/keratin metabolism	18	8.35e-01	9.23e-01	0.1740	-8.78e-03	0.079800	-1.44e-01	-1.92e-03	0.057900	0.949000	0.55800	0.292000	9.89e-01	6.71e-01
Sensory Perception	63	8.36e-01	9.23e-01	0.0954	7.53e-02	0.029800	-5.31e-03	-4.35e-02	-0.024900	0.302000	0.68300	0.942000	5.51e-01	7.33e-01
Gamma carboxylation, hypusine formation and arylsulfatase activation	21	8.37e-01	9.23e-01	0.1990	1.40e-01	0.075200	1.84e-02	9.39e-02	0.073300	0.268000	0.55100	0.884000	4.57e-01	5.61e-01
NoRC negatively regulates rRNA expression	39	8.37e-01	9.23e-01	0.1150	1.90e-02	-0.041000	8.79e-02	4.99e-02	0.029900	0.838000	0.65800	0.343000	5.90e-01	7.47e-01
Amino acid transport across the plasma membrane	16	8.38e-01	9.23e-01	0.1790	8.41e-02	-0.020500	-1.20e-01	-7.70e-02	0.065100	0.560000	0.88700	0.406000	5.94e-01	6.52e-01
Signaling by MET	39	8.40e-01	9.23e-01	0.1380	-4.53e-02	0.037800	-8.57e-03	-1.17e-01	-0.044600	0.625000	0.68400	0.926000	2.08e-01	6.31e-01
Signalling to RAS	12	8.40e-01	9.23e-01	0.2460	4.46e-02	-0.009500	6.21e-03	-1.88e-01	-0.151000	0.789000	0.95500	0.970000	2.59e-01	3.64e-01
NOTCH3 Intracellular Domain Regulates Transcription	15	8.41e-01	9.24e-01	0.2030	-1.15e-02	-0.035400	1.93e-01	-3.87e-02	-0.035600	0.939000	0.81200	0.196000	7.95e-01	8.11e-01
tRNA modification in the nucleus and cytosol	28	8.45e-01	9.26e-01	0.1630	-8.06e-02	-0.105000	8.10e-02	-1.68e-02	0.045300	0.461000	0.33600	0.459000	8.78e-01	6.79e-01
Neutrophil degranulation	288	8.45e-01	9.26e-01	0.0631	-1.33e-02	0.022200	9.62e-03	-3.78e-02	-0.042300	0.700000	0.52100	0.780000	2.74e-01	2.21e-01
SUMOylation of transcription factors	13	8.46e-01	9.26e-01	0.2840	1.97e-01	0.119000	-7.00e-02	8.73e-02	0.123000	0.218000	0.45700	0.662000	5.86e-01	4.43e-01
Nuclear Receptor transcription pathway	26	8.47e-01	9.26e-01	0.1260	-9.22e-02	0.040100	3.13e-03	1.69e-02	-0.073700	0.416000	0.72400	0.978000	8.82e-01	5.16e-01
Synthesis of PIPs at the Golgi membrane	11	8.48e-01	9.26e-01	0.1970	-9.50e-02	-0.092900	2.62e-02	5.53e-02	-0.132000	0.585000	0.59400	0.880000	7.51e-01	4.47e-01
Frs2-mediated activation	11	8.48e-01	9.26e-01	0.2220	-1.61e-02	0.065700	3.50e-02	-1.78e-02	-0.208000	0.926000	0.70600	0.841000	9.19e-01	2.33e-01
MTOR signalling	32	8.51e-01	9.28e-01	0.2060	-8.74e-02	0.018500	9.84e-02	-1.03e-01	-0.119000	0.393000	0.85700	0.336000	3.12e-01	2.44e-01
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	13	8.54e-01	9.31e-01	0.2000	-6.38e-02	0.117000	6.82e-02	-1.34e-01	0.006570	0.691000	0.46700	0.670000	4.05e-01	9.67e-01
Signaling by NTRK3 (TRKC)	10	8.55e-01	9.31e-01	0.2200	1.21e-01	-0.028700	-7.63e-02	-1.37e-01	-0.092000	0.509000	0.87500	0.676000	4.54e-01	6.15e-01
Regulation of cholesterol biosynthesis by SREBP (SREBF)	45	8.57e-01	9.32e-01	0.1400	2.36e-02	0.045000	-6.42e-02	9.20e-02	0.066200	0.784000	0.60200	0.457000	2.86e-01	4.43e-01
Signaling by FGFR2	46	8.59e-01	9.33e-01	0.0924	-6.89e-02	-0.019300	-4.89e-02	3.09e-02	0.008360	0.419000	0.82100	0.566000	7.18e-01	9.22e-01
N-glycan antennae elongation in the medial/trans-Golgi	18	8.62e-01	9.36e-01	0.2050	-6.43e-04	0.139000	-3.17e-02	-1.10e-01	-0.097700	0.996000	0.30600	0.816000	4.20e-01	4.73e-01
TNFR1-induced proapoptotic signaling	12	8.67e-01	9.40e-01	0.1600	8.33e-02	-0.052200	4.09e-02	8.60e-02	-0.082600	0.618000	0.75400	0.807000	6.06e-01	6.21e-01
Inwardly rectifying K+ channels	10	8.69e-01	9.42e-01	0.2340	6.18e-02	0.216000	1.44e-02	-2.67e-02	0.058600	0.735000	0.23700	0.937000	8.84e-01	7.48e-01
Extra-nuclear estrogen signaling	46	8.72e-01	9.43e-01	0.1430	-6.89e-02	0.053500	4.85e-02	-8.44e-02	-0.058400	0.420000	0.53100	0.570000	3.22e-01	4.94e-01
Signaling by TGF-beta Receptor Complex	59	8.73e-01	9.43e-01	0.0818	-1.49e-02	0.013300	-1.09e-02	-3.23e-03	-0.078500	0.843000	0.86000	0.885000	9.66e-01	2.98e-01
Signaling by cytosolic FGFR1 fusion mutants	16	8.73e-01	9.43e-01	0.1420	-8.91e-02	0.087100	-4.02e-02	-3.18e-02	0.044900	0.537000	0.54700	0.781000	8.26e-01	7.56e-01
Pre-NOTCH Transcription and Translation	26	8.75e-01	9.44e-01	0.2070	4.90e-02	-0.006300	-7.02e-02	1.37e-01	0.129000	0.666000	0.95600	0.536000	2.27e-01	2.55e-01
Gap junction trafficking and regulation	10	8.75e-01	9.44e-01	0.3400	-1.54e-01	0.056500	1.06e-01	-1.91e-01	-0.203000	0.400000	0.75700	0.561000	2.96e-01	2.68e-01
Negative regulators of DDX58/IFIH1 signaling	33	8.78e-01	9.46e-01	0.1170	4.23e-02	0.018300	4.22e-02	9.83e-02	0.008130	0.674000	0.85500	0.675000	3.29e-01	9.36e-01
The role of Nef in HIV-1 replication and disease pathogenesis	19	8.79e-01	9.46e-01	0.1970	-2.86e-02	0.024500	-3.20e-02	-1.35e-01	-0.136000	0.829000	0.85400	0.809000	3.09e-01	3.07e-01
Early Phase of HIV Life Cycle	13	8.80e-01	9.46e-01	0.1780	3.65e-03	-0.115000	-7.00e-02	-4.29e-02	-0.109000	0.982000	0.47300	0.662000	7.89e-01	4.97e-01
Prolonged ERK activation events	13	8.80e-01	9.46e-01	0.1950	4.28e-02	0.139000	-9.47e-02	1.47e-02	-0.088500	0.789000	0.38700	0.555000	9.27e-01	5.81e-01
Termination of O-glycan biosynthesis	10	8.84e-01	9.49e-01	0.2130	4.33e-02	0.015000	2.25e-02	2.05e-01	0.024800	0.813000	0.93500	0.902000	2.62e-01	8.92e-01
Signaling by NOTCH1	51	8.89e-01	9.53e-01	0.0860	-2.16e-03	0.016000	1.24e-02	8.34e-02	0.005280	0.979000	0.84300	0.879000	3.03e-01	9.48e-01
Aggrephagy	19	8.96e-01	9.60e-01	0.1610	-9.18e-02	-0.089700	-7.79e-02	2.90e-02	0.051500	0.489000	0.49900	0.557000	8.27e-01	6.98e-01
Unwinding of DNA	10	8.98e-01	9.61e-01	0.2160	1.32e-01	-0.044300	3.87e-02	1.55e-01	0.039300	0.470000	0.80800	0.832000	3.95e-01	8.30e-01
Sphingolipid metabolism	43	9.01e-01	9.64e-01	0.1040	-8.10e-03	0.072400	6.72e-02	2.04e-02	-0.024800	0.927000	0.41200	0.446000	8.17e-01	7.79e-01
Activation of HOX genes during differentiation	36	9.05e-01	9.65e-01	0.1070	-5.73e-02	0.024900	7.43e-02	4.34e-02	-0.009890	0.553000	0.79600	0.441000	6.53e-01	9.18e-01
Activation of anterior HOX genes in hindbrain development during early embryogenesis	36	9.05e-01	9.65e-01	0.1070	-5.73e-02	0.024900	7.43e-02	4.34e-02	-0.009890	0.553000	0.79600	0.441000	6.53e-01	9.18e-01
Formation of HIV elongation complex in the absence of HIV Tat	31	9.08e-01	9.65e-01	0.1330	3.93e-02	-0.052100	2.88e-02	6.42e-02	0.091800	0.705000	0.61600	0.781000	5.37e-01	3.77e-01
Formation of HIV-1 elongation complex containing HIV-1 Tat	31	9.08e-01	9.65e-01	0.1330	3.93e-02	-0.052100	2.88e-02	6.42e-02	0.091800	0.705000	0.61600	0.781000	5.37e-01	3.77e-01
HIV Transcription Elongation	31	9.08e-01	9.65e-01	0.1330	3.93e-02	-0.052100	2.88e-02	6.42e-02	0.091800	0.705000	0.61600	0.781000	5.37e-01	3.77e-01
Tat-mediated elongation of the HIV-1 transcript	31	9.08e-01	9.65e-01	0.1330	3.93e-02	-0.052100	2.88e-02	6.42e-02	0.091800	0.705000	0.61600	0.781000	5.37e-01	3.77e-01
Negative epigenetic regulation of rRNA expression	40	9.10e-01	9.67e-01	0.0975	1.70e-02	-0.044500	6.89e-02	3.68e-02	0.033700	0.852000	0.62700	0.451000	6.87e-01	7.13e-01
Downregulation of TGF-beta receptor signaling	25	9.12e-01	9.67e-01	0.1590	1.03e-01	0.100000	-3.74e-02	9.05e-03	0.055100	0.371000	0.38500	0.746000	9.38e-01	6.33e-01
Interleukin-17 signaling	49	9.12e-01	9.67e-01	0.0860	-5.64e-02	0.056200	2.28e-02	5.60e-03	-0.022600	0.495000	0.49600	0.783000	9.46e-01	7.85e-01
mTORC1-mediated signalling	17	9.14e-01	9.67e-01	0.1870	-8.38e-02	0.053500	7.10e-02	-3.31e-02	-0.138000	0.550000	0.70300	0.613000	8.13e-01	3.26e-01
Signaling by BRAF and RAF fusions	42	9.15e-01	9.67e-01	0.1190	2.62e-02	0.103000	4.60e-03	-4.02e-02	-0.034800	0.769000	0.24900	0.959000	6.52e-01	6.97e-01
Inactivation, recovery and regulation of the phototransduction cascade	16	9.16e-01	9.67e-01	0.1660	4.84e-02	0.151000	2.43e-02	-3.28e-02	0.028100	0.738000	0.29600	0.867000	8.20e-01	8.46e-01
The phototransduction cascade	16	9.16e-01	9.67e-01	0.1660	4.84e-02	0.151000	2.43e-02	-3.28e-02	0.028100	0.738000	0.29600	0.867000	8.20e-01	8.46e-01
Nephrin family interactions	14	9.22e-01	9.73e-01	0.1940	-2.32e-02	0.023900	6.03e-03	-1.76e-01	-0.073500	0.880000	0.87700	0.969000	2.54e-01	6.34e-01
RAC1 GTPase cycle	102	9.25e-01	9.75e-01	0.0607	3.41e-02	0.032400	3.53e-02	1.49e-02	0.001670	0.553000	0.57300	0.539000	7.95e-01	9.77e-01
NR1H2 and NR1H3-mediated signaling	24	9.26e-01	9.75e-01	0.1460	2.05e-02	0.046200	1.01e-01	-3.61e-02	-0.084600	0.862000	0.69500	0.391000	7.60e-01	4.74e-01
RHO GTPases Activate ROCKs	13	9.27e-01	9.75e-01	0.2050	-2.78e-02	-0.043300	6.50e-02	-7.92e-02	-0.170000	0.862000	0.78700	0.685000	6.21e-01	2.90e-01
RHOBTB2 GTPase cycle	19	9.28e-01	9.76e-01	0.1880	-1.50e-01	-0.043200	8.75e-02	-3.45e-02	-0.042800	0.257000	0.74500	0.509000	7.95e-01	7.47e-01
Transport of vitamins, nucleosides, and related molecules	21	9.31e-01	9.78e-01	0.1710	1.31e-01	-0.014900	-6.62e-02	7.68e-02	0.041600	0.300000	0.90600	0.600000	5.42e-01	7.41e-01
PIWI-interacting RNA (piRNA) biogenesis	14	9.33e-01	9.78e-01	0.1790	7.21e-02	0.140000	7.66e-02	-2.15e-02	-0.033700	0.641000	0.36600	0.620000	8.89e-01	8.27e-01
Mitophagy	25	9.33e-01	9.78e-01	0.1130	5.79e-02	-0.014000	-2.12e-02	-4.58e-02	-0.082000	0.616000	0.90400	0.854000	6.92e-01	4.78e-01
Regulation of beta-cell development	15	9.38e-01	9.82e-01	0.1670	-5.59e-02	-0.120000	8.43e-02	5.47e-02	-0.014400	0.708000	0.42200	0.572000	7.14e-01	9.23e-01
FGFR2 mutant receptor activation	15	9.39e-01	9.82e-01	0.1390	-1.04e-01	0.028100	5.62e-02	3.36e-02	0.059300	0.486000	0.85100	0.707000	8.22e-01	6.91e-01
Abortive elongation of HIV-1 transcript in the absence of Tat	17	9.43e-01	9.82e-01	0.1300	-1.27e-02	0.077400	-1.98e-02	2.31e-02	0.098400	0.928000	0.58100	0.888000	8.69e-01	4.83e-01
ADP signalling through P2Y purinoceptor 1	13	9.46e-01	9.82e-01	0.1650	-1.41e-01	0.000640	-2.12e-02	-7.47e-02	-0.037800	0.379000	0.99700	0.895000	6.41e-01	8.14e-01
Lysosome Vesicle Biogenesis	24	9.49e-01	9.82e-01	0.1620	8.50e-02	0.004500	-1.19e-01	3.89e-02	0.057600	0.471000	0.97000	0.313000	7.42e-01	6.25e-01
PINK1-PRKN Mediated Mitophagy	20	9.49e-01	9.82e-01	0.1340	4.83e-02	0.077700	8.79e-02	-1.85e-02	-0.040500	0.709000	0.54800	0.497000	8.86e-01	7.54e-01
RHO GTPase cycle	271	9.51e-01	9.82e-01	0.0443	-8.20e-03	0.020800	3.07e-02	-1.25e-02	-0.019100	0.818000	0.55800	0.388000	7.26e-01	5.92e-01
Heme biosynthesis	10	9.51e-01	9.82e-01	0.1720	1.16e-01	-0.000588	4.16e-02	1.19e-01	0.009860	0.524000	0.99700	0.820000	5.14e-01	9.57e-01
TAK1 activates NFkB by phosphorylation and activation of IKKs complex	16	9.51e-01	9.82e-01	0.1450	-8.30e-02	-0.015800	-2.28e-02	-4.10e-02	-0.108000	0.566000	0.91300	0.875000	7.77e-01	4.54e-01
Notch-HLH transcription pathway	21	9.51e-01	9.82e-01	0.1470	3.95e-02	0.083700	5.09e-02	-4.35e-02	-0.092700	0.754000	0.50700	0.687000	7.30e-01	4.62e-01
Intrinsic Pathway for Apoptosis	44	9.53e-01	9.82e-01	0.0652	1.22e-02	0.017700	-4.57e-03	-5.78e-02	0.020500	0.889000	0.83900	0.958000	5.08e-01	8.14e-01
Downstream signaling of activated FGFR1	11	9.54e-01	9.82e-01	0.2160	4.00e-03	0.118000	1.59e-02	-1.42e-01	-0.112000	0.982000	0.49900	0.927000	4.16e-01	5.21e-01
Downstream signaling of activated FGFR2	11	9.54e-01	9.82e-01	0.2160	4.00e-03	0.118000	1.59e-02	-1.42e-01	-0.112000	0.982000	0.49900	0.927000	4.16e-01	5.21e-01
Downstream signaling of activated FGFR3	11	9.54e-01	9.82e-01	0.2160	4.00e-03	0.118000	1.59e-02	-1.42e-01	-0.112000	0.982000	0.49900	0.927000	4.16e-01	5.21e-01
Downstream signaling of activated FGFR4	11	9.54e-01	9.82e-01	0.2160	4.00e-03	0.118000	1.59e-02	-1.42e-01	-0.112000	0.982000	0.49900	0.927000	4.16e-01	5.21e-01
Signaling by Hippo	11	9.54e-01	9.82e-01	0.1870	3.62e-02	-0.010800	-1.64e-01	-2.77e-03	0.082400	0.836000	0.95100	0.348000	9.87e-01	6.36e-01
Kinesins	30	9.54e-01	9.82e-01	0.0848	3.80e-02	0.000779	6.65e-02	-3.61e-02	-0.003730	0.719000	0.99400	0.529000	7.32e-01	9.72e-01
Diseases associated with the TLR signaling cascade	16	9.54e-01	9.82e-01	0.1640	-8.14e-02	0.097600	6.94e-02	-4.59e-02	-0.061700	0.573000	0.49900	0.631000	7.51e-01	6.70e-01
Diseases of Immune System	16	9.54e-01	9.82e-01	0.1640	-8.14e-02	0.097600	6.94e-02	-4.59e-02	-0.061700	0.573000	0.49900	0.631000	7.51e-01	6.70e-01
CTLA4 inhibitory signaling	15	9.56e-01	9.82e-01	0.1870	-7.63e-02	0.045200	9.11e-02	-1.26e-01	-0.055500	0.609000	0.76200	0.542000	3.99e-01	7.10e-01
Cleavage of the damaged pyrimidine	13	9.57e-01	9.82e-01	0.2020	-1.43e-01	-0.030500	3.61e-02	-7.85e-02	-0.109000	0.372000	0.84900	0.822000	6.24e-01	4.98e-01
Depyrimidination	13	9.57e-01	9.82e-01	0.2020	-1.43e-01	-0.030500	3.61e-02	-7.85e-02	-0.109000	0.372000	0.84900	0.822000	6.24e-01	4.98e-01
Recognition and association of DNA glycosylase with site containing an affected pyrimidine	13	9.57e-01	9.82e-01	0.2020	-1.43e-01	-0.030500	3.61e-02	-7.85e-02	-0.109000	0.372000	0.84900	0.822000	6.24e-01	4.98e-01
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	11	9.57e-01	9.82e-01	0.1410	4.90e-02	-0.057800	8.31e-02	8.44e-02	-0.014000	0.779000	0.74000	0.633000	6.28e-01	9.36e-01
Interleukin-35 Signalling	11	9.58e-01	9.82e-01	0.1740	1.38e-01	0.022100	-3.83e-02	3.04e-03	0.097000	0.429000	0.89900	0.826000	9.86e-01	5.78e-01
Glucose metabolism	69	9.59e-01	9.82e-01	0.0590	-2.54e-02	-0.031000	1.80e-02	2.03e-02	-0.033800	0.715000	0.65700	0.797000	7.71e-01	6.28e-01
Signaling by FGFR2 IIIa TM	14	9.61e-01	9.82e-01	0.1410	-8.08e-02	-0.017200	5.75e-02	4.32e-02	0.088000	0.601000	0.91100	0.709000	7.80e-01	5.69e-01
O-linked glycosylation of mucins	26	9.62e-01	9.82e-01	0.1050	-1.35e-02	-0.016100	-5.90e-02	-6.57e-02	-0.053300	0.905000	0.88700	0.603000	5.63e-01	6.38e-01
Visual phototransduction	32	9.63e-01	9.82e-01	0.0929	3.68e-02	0.024200	-7.06e-02	-5.01e-03	-0.041000	0.719000	0.81300	0.490000	9.61e-01	6.89e-01
Synthesis of PA	17	9.64e-01	9.82e-01	0.1370	6.35e-02	0.103000	-2.81e-03	5.56e-03	0.062800	0.650000	0.46200	0.984000	9.68e-01	6.54e-01
Signaling by CSF3 (G-CSF)	25	9.64e-01	9.82e-01	0.1380	-3.00e-02	0.051300	9.69e-03	-7.40e-02	-0.100000	0.796000	0.65700	0.933000	5.22e-01	3.86e-01
G beta:gamma signalling through PLC beta	10	9.65e-01	9.82e-01	0.2180	-4.04e-02	0.117000	7.80e-02	-1.34e-01	-0.090500	0.825000	0.52300	0.669000	4.64e-01	6.20e-01
Presynaptic function of Kainate receptors	10	9.65e-01	9.82e-01	0.2180	-4.04e-02	0.117000	7.80e-02	-1.34e-01	-0.090500	0.825000	0.52300	0.669000	4.64e-01	6.20e-01
TRAF6 mediated NF-kB activation	17	9.65e-01	9.82e-01	0.1500	-9.05e-02	-0.069400	8.08e-02	1.42e-02	-0.053400	0.518000	0.62000	0.564000	9.19e-01	7.03e-01
SUMOylation of intracellular receptors	19	9.69e-01	9.84e-01	0.0998	8.68e-02	-0.010900	2.62e-02	3.62e-02	-0.017500	0.513000	0.93500	0.843000	7.85e-01	8.95e-01
NOTCH1 Intracellular Domain Regulates Transcription	37	9.72e-01	9.86e-01	0.1000	-2.75e-02	-0.018500	8.64e-02	-2.61e-02	-0.028700	0.772000	0.84600	0.364000	7.84e-01	7.63e-01
Response of EIF2AK1 (HRI) to heme deficiency	13	9.78e-01	9.91e-01	0.1390	9.93e-02	0.053800	-5.58e-02	-5.83e-02	-0.012500	0.536000	0.73700	0.728000	7.16e-01	9.38e-01
CDC42 GTPase cycle	91	9.78e-01	9.91e-01	0.0548	2.06e-02	0.042900	-1.84e-02	3.64e-03	-0.019600	0.734000	0.48100	0.763000	9.52e-01	7.48e-01
TGF-beta receptor signaling activates SMADs	30	9.83e-01	9.95e-01	0.1130	7.50e-02	-0.012800	-6.24e-02	3.68e-02	0.040600	0.477000	0.90400	0.555000	7.28e-01	7.01e-01
Interleukin-15 signaling	11	9.84e-01	9.95e-01	0.1300	9.96e-02	0.073900	2.76e-02	-2.49e-02	0.015900	0.567000	0.67100	0.874000	8.87e-01	9.27e-01
Signaling by FGFR2 in disease	22	9.85e-01	9.96e-01	0.0908	1.33e-02	0.067500	-4.08e-02	-4.20e-02	0.009030	0.914000	0.58400	0.740000	7.33e-01	9.42e-01
Purine salvage	11	9.88e-01	9.97e-01	0.1230	9.74e-03	0.094200	2.65e-02	-7.32e-02	0.001510	0.955000	0.58900	0.879000	6.74e-01	9.93e-01
Glycosphingolipid metabolism	25	9.89e-01	9.97e-01	0.0708	6.44e-03	-0.024500	-2.54e-03	-6.59e-02	-0.004180	0.956000	0.83300	0.982000	5.69e-01	9.71e-01
Autophagy	95	9.90e-01	9.98e-01	0.0572	2.76e-02	-0.011600	-1.31e-02	3.77e-02	0.027800	0.642000	0.84500	0.825000	5.27e-01	6.40e-01
Peptide hormone metabolism	23	9.91e-01	9.98e-01	0.0720	-8.07e-03	-0.025500	5.62e-02	-3.34e-02	0.014200	0.947000	0.83300	0.641000	7.82e-01	9.06e-01
Transcriptional Regulation by E2F6	28	9.92e-01	9.98e-01	0.0598	2.10e-02	0.029000	-1.37e-02	-2.52e-02	0.038500	0.848000	0.79100	0.901000	8.18e-01	7.25e-01
Regulation of RUNX1 Expression and Activity	12	9.93e-01	9.98e-01	0.1470	-2.80e-02	0.061100	3.36e-02	-7.22e-02	-0.104000	0.867000	0.71400	0.841000	6.65e-01	5.35e-01
Pre-NOTCH Expression and Processing	40	9.94e-01	9.98e-01	0.0408	-1.45e-02	0.019100	-1.25e-02	2.05e-02	-0.022700	0.874000	0.83500	0.892000	8.23e-01	8.04e-01
Metabolism of nucleotides	68	9.95e-01	9.98e-01	0.0555	-2.81e-02	0.019900	1.69e-02	-2.31e-02	-0.032900	0.689000	0.77700	0.809000	7.42e-01	6.40e-01
Inactivation of CSF3 (G-CSF) signaling	20	9.96e-01	9.98e-01	0.0794	2.76e-02	0.049200	8.46e-03	-1.09e-02	-0.054100	0.831000	0.70300	0.948000	9.33e-01	6.76e-01
Macroautophagy	87	9.97e-01	9.98e-01	0.0357	2.90e-02	-0.004780	-5.09e-03	1.94e-02	0.003450	0.641000	0.93900	0.935000	7.55e-01	9.56e-01
Metabolism	1168	9.97e-01	9.98e-01	0.0139	8.18e-03	0.001770	-4.46e-03	8.58e-03	0.005330	0.649000	0.92200	0.804000	6.33e-01	7.67e-01
FGFR2 alternative splicing	21	9.99e-01	9.99e-01	0.0455	-2.97e-02	0.014100	-9.22e-03	2.90e-02	0.008310	0.814000	0.91100	0.942000	8.18e-01	9.47e-01

---

Detailed Gene set reports

Metabolism of RNA

Metabolism of RNA

metric	value
setSize	498
pMANOVA	2.6e-12
p.adjustMANOVA	2.96e-09
s.dist	0.21
s.psf	-0.0684
s.psb	-0.0684
s.hcy	0.0942
s.folate	0.128
s.vitb12	0.0972
p.psf	0.01
p.psb	0.00996
p.hcy	0.000388
p.folate	1.38e-06
p.vitb12	0.000252

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
NCBP1	8402	8509
GLE1	8318	8571
CWC22	8283	8440
CSNK1E	7983	8577
RPS27A	8228	8264
RPS24	7985	8504
RNU12	8329	8148
GEMIN6	7934	8489
SF3A2	7866	8539
NUP35	8140	8243
PES1	8341	8026
SNRPC	8378	7966
SNRPN	8320	8000
DNAJC8	7931	8344
RPSA	8071	8168
RNU11	8142	8094
RPL15	7772	8423
RPL34	7954	8213
PSMA3	8188	7955
UTP20	7701	8426

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
AAAS	-4813	-3658	2354	1828	2776
ACTB	-6208	-3505	4760	-298	1025
ADAR	-7605	-5586	5502	1168	1181
ADARB1	-2259	-822	-65	722	6613
ADAT1	-7974	-7920	6194	4927	3779
ADAT2	-2468	-4319	3643	1991	3897
ADAT3	-3376	-611	6196	1906	2295
AKT1	-8746	-7641	4880	-1052	2534
ALKBH8	-5501	-8537	1192	5418	5389
ANP32A	-7399	-6403	-2286	658	5700
AQR	-6333	-3041	3130	2428	213
BMS1	-2776	-2778	-2326	3878	2450
BUD31	-5822	-1257	5663	1158	-128
BYSL	-4178	-9536	6111	7563	8099
C1D	-3010	-6362	1064	7585	8248
C2orf49	-5877	-9356	4492	6328	3899
CASC3	-5894	-3543	-120	2750	7789
CCAR1	-6114	-4153	4117	2954	1555
CCNH	-5123	-6984	5835	888	1368
CD2BP2	-7752	-6379	-565	2299	225
CD44	-6852	-2768	4090	1077	2290
CDC40	-5069	-5170	6113	7236	7911
CDC5L	-3718	-8684	2708	4035	466
CDK7	-1359	-7416	1957	8195	7509
CDKAL1	-2283	-6531	4062	7908	8174
CHERP	-1036	-1544	150	7588	7250
CLNS1A	-4049	-8440	-850	3571	4678
CLP1	-8309	-8541	3767	4503	5311
CNOT1	-4466	-7905	515	3125	894
CNOT10	-7616	-7973	2180	1000	2241
CNOT3	-4798	-1141	4938	1955	1905
CNOT4	-7676	-6822	6398	1813	666
CNOT6	-6918	-2723	2360	634	5188
CNOT6L	-7146	-3152	4701	5569	4998
CNOT7	-5868	59	-1484	8204	6986
CNOT8	-3866	-6318	762	5785	6943
CPSF1	-7857	-2180	1761	-275	3766
CPSF2	-8923	-7853	5634	4004	1174
CPSF3	-9106	-320	3820	-995	-1008
CPSF4	-2416	-2946	3597	65	1707
CRNKL1	-8653	-1313	6082	4891	-53
CSNK1D	-973	-7670	2239	1107	4901
CSNK1E	614	-3165	-729	7983	8577
CSTF1	-8368	-1269	6211	3962	-798
CTNNBL1	-260	-2124	-1675	5289	7206
CTU1	-8484	-6051	3145	2912	2705
CTU2	-1100	-2629	6346	-1305	4162
CWC15	-5234	-9143	500	5096	5887
CWC22	-2356	-1364	-624	8283	8440
DCAF13	-5830	-1699	3821	6595	7638
DCP1A	-4668	-4529	1204	4837	3403
DCP1B	73	-4296	-1919	7016	6904
DCP2	-8598	-4221	4207	1533	-563
DCPS	49	-685	3883	5228	3390
DDX1	-3153	-2141	1620	1753	137
DDX20	-6978	-7050	4653	4703	3279
DDX21	-5888	-3897	3188	3469	6682
DDX23	-5303	-5813	1255	6302	2957
DDX42	-6054	-3242	-750	7469	7080
DDX46	-3736	-5546	1628	489	170
DDX47	334	-4037	-1806	8287	6894
DDX49	-4822	-5792	5371	-412	788
DDX5	-8798	-1962	5815	765	8110
DDX52	-4300	-7923	2602	7367	8105
DDX6	-3355	-2717	1690	3031	1700
DHX16	-6357	-5208	3655	2330	1654
DHX37	-7569	-4973	5147	689	58
DHX9	-2881	-5212	3182	2843	5648
DIS3	-8552	-9237	3964	2928	1121
DNAJC8	-7353	-9020	341	7931	8344
EBNA1BP2	-8700	-8946	1196	3873	5515
EDC3	-3476	-2113	79	6434	7691
EDC4	-1366	-218	-2072	7800	6122
EFTUD2	-6446	-4389	556	371	6704
EIF4A1	-1333	-1250	3847	5915	4073
EIF4A2	-2633	-5470	2412	8016	6992
EIF4A3	-1889	-241	4502	5779	4014
EIF4B	-7712	-3860	3758	2671	3062
EIF4E	-2494	-478	798	-590	2108
EIF4G1	-2868	-940	4004	1882	-227
ELAC2	-1211	-5657	-1752	7506	7313
ENPP2	-8543	-9210	1215	3135	7904
ERCC2	-2032	-7664	-2080	7313	4655
ERCC3	-5716	-8505	128	4023	3726
ERI1	-6742	-8109	4581	-851	-677
ETF1	-5256	-1911	4663	-25	4397
EXOSC10	-1296	-2277	1561	7129	5838
EXOSC2	-8729	-9244	2530	3525	4504
EXOSC3	-1149	-6526	748	501	4842
EXOSC4	-5949	-971	3231	1277	-86
EXOSC5	-6533	-4703	1943	-485	-100
EXOSC6	-1630	-2864	1276	6042	4034
EXOSC7	-8091	-8183	3484	4662	6982
EXOSC8	-8053	-4017	6064	3443	6272
FAM98B	-7647	-8763	4802	3772	5337
FAU	-7265	-3975	4740	233	1443
FBL	-1016	-3458	-2129	7793	7043
FCF1	-388	-3791	-123	6479	8244
FIP1L1	-3659	-5017	3181	598	4518
FTSJ3	-6448	-1225	-1655	4146	6605
FUS	-8674	-8601	5569	646	297
FYTTD1	-7249	-4238	5845	314	-862
GAR1	-3275	-7493	2470	7687	6649
GEMIN5	-5560	-2746	-1005	2733	-95
GEMIN6	-2353	-8761	-204	7934	8489
GEMIN7	-1065	-8185	1126	7971	1616
GLE1	666	-7622	-1801	8318	8571
GNL3	-2576	-2510	3435	216	3410
GSPT1	-2286	-956	-604	2009	-353
GTF2F1	-6478	-3375	-601	1836	7032
GTF2F2	-4911	-5801	2754	5927	6569
GTF2H3	-965	-6464	-2196	1021	5377
GTF2H4	-195	-4568	3621	2685	2771
GTF2H5	-111	-8023	2512	-35	7324
GTPBP3	-1186	-1503	-733	6011	6702
HBS1L	-8181	-8135	3760	7361	6683
HEATR1	-4869	-3287	2084	3939	6174
HNRNPA0	-3798	-5600	3243	1046	969
HNRNPA2B1	-5709	-2656	1320	2348	6171
HNRNPC	-6417	-4531	-444	7786	5488
HNRNPD	-4568	-1459	4662	3947	2001
HNRNPF	-4034	-5253	2984	1175	1921
HNRNPH1	-5132	-5113	6459	7063	112
HNRNPK	-8708	-3748	2280	5391	2404
HNRNPL	-2126	-3202	1676	2831	630
HNRNPM	-2262	-6986	-2261	3606	6840
HNRNPR	-8622	-2736	6282	-218	176
HNRNPU	-3813	-1254	860	5008	5617
HNRNPUL1	-3147	-3194	4088	5579	5341
HSPA1A	-8087	-7146	832	3274	3761
HSPB1	-4280	-4321	-1219	159	6639
IGF2BP1	519	-471	-2689	5883	4657
IGF2BP3	-8843	-8349	5091	2812	-508
IMP3	-6465	-6229	388	4395	4138
IMP4	-1644	-5137	-220	5827	4713
ISG20L2	-7334	-1485	5735	997	-952
ISY1	-7742	-8825	5271	5327	3431
KHSRP	-7489	-9255	4404	558	-20
LCMT2	-5205	61	-2864	1719	5430
LSM1	-5516	-8029	5279	2373	4857
LSM10	324	-5259	-1414	7694	5655
LSM11	-1169	-1272	2016	3268	134
LSM2	-2021	-1145	-593	6198	4951
LSM3	-2989	-3969	-1227	4544	7387
LSM4	-8436	-1999	5635	3901	3659
LSM5	-6751	-6566	2041	3840	3828
LSM6	-5542	-4880	3191	6797	2059
LSM7	-4523	-8629	-859	6494	-776
LTV1	-4883	-1561	662	6380	6318
MAPK14	-7648	-3775	1942	1668	1054
MAPKAPK2	-6467	-6863	2498	2575	888
METTL1	-3185	-9006	878	3365	5624
METTL14	-8615	-8682	1352	62	5452
MNAT1	-192	-5911	5844	7743	7276
MPHOSPH10	-8327	-4667	4534	1092	-150
MPHOSPH6	-4444	-3883	2630	6246	6385
MRM1	-7788	-3515	2510	3590	5871
MTO1	-8669	-8883	926	594	2790
NCBP1	-2607	-1945	2448	8402	8509
NCBP2	-3917	-5147	2973	6756	7623
NCL	-5736	-2460	2823	872	2137
NHP2	-6903	-5797	4423	301	373
NIP7	-8733	-7995	4984	820	-21
NOB1	-1208	-2611	-131	4405	4604
NOC4L	-6156	-4743	-1501	665	502
NOL11	-4583	-2640	2367	3213	3045
NOL12	-8329	-7236	2920	4088	7991
NOL6	-7508	-8624	-40	4802	4970
NOP10	-1349	-8584	5068	5553	7616
NOP14	649	185	3743	2648	-494
NOP2	-5068	-5446	-489	904	6520
NOP56	-5280	-7733	2511	1724	4467
NOP58	-8048	-1193	4754	1322	6909
NSUN2	-7068	-3927	5364	618	-552
NSUN4	-6033	-4663	-748	3736	5054
NSUN6	241	-7675	846	7900	7990
NUDT21	-8225	-7782	5559	3640	1124
NUP107	-2367	-5920	902	8020	7981
NUP133	-2192	-6208	-1034	6710	4350
NUP153	-4611	-8419	2123	1709	5952
NUP155	-938	-2261	778	3101	6606
NUP160	-4062	-2126	-1133	5658	7516
NUP188	-4111	-2994	3510	3714	3909
NUP205	-8245	-8394	4686	6267	6798
NUP210	-8192	-8465	2605	2001	-159
NUP214	-3272	-1704	2474	2228	1116
NUP35	-1551	-7219	-1373	8140	8243
NUP37	-7550	-421	4573	1438	1480
NUP43	-5408	-4131	4558	2582	2522
NUP50	-4714	-688	2999	1921	1935
NUP54	-1931	-4958	3515	3754	3208
NUP62	-1453	-8038	1978	7023	5407
NUP85	-7303	-8224	5526	3668	1520
NUP93	-3267	-3790	-2168	3175	6994
NUP98	-8199	-889	2149	7764	7066
NXF1	-6326	-5554	4304	6707	3030
NXT1	-6627	-8867	1191	2961	710
PABPC1	-3400	-5506	4238	5582	1293
PABPN1	-5567	-8318	2534	6672	2442
PAIP1	-3261	-3774	-2670	7052	1413
PAN2	-7232	-7677	-178	7799	7556
PAN3	-7854	-12	-2829	6662	7339
PAPOLA	-8227	-6469	2436	1653	2471
PARN	-939	-2441	35	7647	7550
PATL1	-5692	-3470	498	604	4263
PCBP1	-2567	-3030	182	6928	6076
PCBP2	-4517	-2508	4187	3727	1131
PDCD11	-2614	-3039	1969	4218	1847
PDCD7	-4272	-3341	3565	6212	3034
PELP1	-4092	-3704	3720	4290	5506
PES1	-2938	-8904	-2265	8341	8026
PHAX	491	-3474	-1487	6753	3507
PLRG1	-6202	-6583	4035	1766	5014
PNO1	-3481	-5763	266	5053	4129
PNRC2	-4158	-6285	2483	96	54
POLDIP3	-3702	-6669	1702	7198	7721
POLR2A	-8657	-6301	3361	1117	-706
POLR2B	-2551	-7510	1297	5291	7059
POLR2C	-375	-2722	2661	3775	1272
POLR2D	-4623	-6633	1251	-240	862
POLR2E	-7280	-5905	1641	2768	1465
POLR2F	-2647	22	2490	337	2732
POLR2G	-3892	-6713	3633	6708	4000
POLR2H	-3216	-2022	5045	1005	994
POLR2I	-6360	-3343	1067	691	4207
POLR2K	-6692	-9353	-599	7535	6282
POM121	-6127	-7922	5593	4069	6325
POM121C	-3786	-5219	3938	5072	3069
POP1	-4725	-5302	5051	-251	2929
POP4	-1264	-341	3877	5860	1270
POP5	-6480	-8909	3856	3562	1612
POP7	-5711	-7079	-644	4929	1463
PPIE	-3912	-9284	-319	4108	2543
PPIH	-7408	-5442	4546	4252	3083
PPIL1	-4920	-7462	3201	5396	1591
PPIL3	-6835	-2869	3210	6931	7856
PPIL4	-2779	-5560	1024	2797	3962
PPIL6	-9118	-7739	6689	7640	2461
PPP2CA	-4081	-3471	4425	2847	2701
PPP2R2A	-144	-5849	1125	5472	6709
PPWD1	-5342	-492	37	143	2520
PRCC	-4588	-8058	417	7046	4634
PRKCA	-5820	-4955	3971	3486	5016
PRKCD	-6607	-1968	5933	-938	2142
PRMT5	-4742	-9448	38	6109	6609
PRPF19	-4491	-7879	1425	5393	5122
PRPF3	-4650	-4881	-1404	8106	7172
PRPF31	-2670	-8967	-2121	7586	8477
PRPF38A	-2486	-8964	-1546	2573	3523
PRPF6	-1239	-6227	4827	4948	8123
PRPF8	-7782	-8620	4488	1852	1835
PSMA1	-8359	-8604	5104	1855	4650
PSMA2	-7938	-2161	5110	1432	8018
PSMA3	-2004	-4530	4184	8188	7955
PSMA5	-3753	-5163	4135	7049	6792
PSMA6	-5756	-9052	230	3273	5895
PSMA7	-5963	-1772	3526	2927	3736
PSMB1	-2258	-1758	1218	4974	2620
PSMB10	-1663	-6710	-165	6829	6594
PSMB3	-3839	-6905	4780	5497	4412
PSMB5	-89	-6668	-1101	7598	7952
PSMB6	-6634	-5888	2326	6558	5006
PSMB7	-5105	-6476	-481	6667	7933
PSMB8	-7792	-3686	5160	756	1587
PSMB9	-8032	-7032	4898	3199	1447
PSMC1	89	-6196	611	7227	6270
PSMC3	-4234	-5168	-1757	3247	5525
PSMC4	-5962	-6708	1563	2130	2138
PSMC5	-7766	-7267	5418	2470	428
PSMC6	-7087	-7964	4301	5996	2878
PSMD1	-1790	-8089	458	4661	6182
PSMD11	-1272	-2207	4285	6544	4390
PSMD12	-2535	-3717	20	7015	7973
PSMD13	-8546	-5774	4927	2662	-882
PSMD14	-2548	-5579	3518	3709	4574
PSMD2	-7305	-6402	3485	3621	4835
PSMD3	-6151	-6416	5506	2545	2496
PSMD4	-7964	-5567	754	5325	7149
PSMD6	-4518	-717	1908	2403	114
PSMD7	-3120	-8646	2963	5075	5520
PSMD8	-4369	-5263	1397	3011	5309
PSMD9	-1075	-5374	3215	4605	1840
PSME1	-4828	-2498	2379	209	820
PSME2	-3988	-5227	2344	6844	5159
PSME3	-502	-1677	210	3994	6092
PSME4	-4990	-8991	5997	207	-839
PSMF1	-490	-5529	-2618	4670	8624
PTBP1	-813	-1190	921	4122	2968
PUF60	-1473	-835	2132	-56	3923
PUS1	-4723	-6609	6583	-1191	1778
PUS3	349	-1137	-2850	8141	3269
PUS7	-3740	-4067	1771	4126	3756
PWP2	-7581	-2679	4980	608	-496
QTRT1	-5676	-5623	-1309	5490	6476
RAE1	-8303	-1469	2950	2287	4628
RAN	215	-1000	-1174	7323	7330
RANBP2	-3530	-4429	-1283	4903	6045
RBM17	-6730	-4323	5818	-372	2782
RBM28	-492	-4862	-522	3026	7719
RCL1	-4719	-6386	-1205	8222	2198
RIOK1	-869	-7955	-497	2384	8560
RIOK2	-4653	-8102	2370	7755	8233
RIOK3	-6720	-3909	348	1192	5569
RNGTT	-4968	-8144	3170	4613	7834
RNMT	-7124	-348	258	3703	5261
RNPC3	-5347	-4075	893	2772	7405
RNPS1	-5625	-5883	3685	2173	1138
RNU11	-4042	-8053	1371	8142	8094
RNU12	-6802	-790	-300	8329	8148
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPP14	-6182	-3689	2495	7012	4934
RPP21	-4699	-6536	906	1823	4298
RPP25	-4651	-7431	-2548	991	3559
RPP30	-4130	-8638	3731	7603	7125
RPP38	-6757	-3693	5497	823	-465
RPP40	-7953	-7432	5100	-457	-660
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
RRP1	-4052	-2434	-355	1248	3362
RRP7A	-434	-3767	-483	5962	7569
RRP9	-6069	-5735	5668	1022	3846
SART1	-2739	-4566	-653	6130	5049
SEC13	-8747	-6731	4873	-516	1432
SEH1L	-7723	-5493	4691	844	4470
SENP3	517	-4315	-2379	4693	3631
SET	-7638	-9528	-2876	7004	5720
SF1	-4832	-3244	1384	3310	4619
SF3A1	-6165	-5622	5669	-202	298
SF3A2	-159	-1064	5388	7866	8539
SF3A3	-3923	-5941	2407	2044	2601
SF3B2	-3556	-4464	3956	4587	3040
SF3B3	417	-9037	-2254	4250	5408
SF3B4	-1361	-7842	-2440	6419	7910
SF3B5	-3889	-860	5471	6211	5269
SKIV2L	-6148	-4626	3233	3863	1325
SLBP	-4277	-4143	4482	6615	1359
SLU7	-7719	-1038	4816	2793	7622
SMG1	-2541	-1365	1838	6991	3347
SMG5	-6338	-8564	1537	7295	5964
SMG7	-5648	-5578	5198	1498	-49
SMNDC1	-4988	-6052	2616	6156	5660
SNRNP200	-8215	-3814	6366	3481	731
SNRNP25	-6385	-7763	4650	2423	-671
SNRNP27	-8613	-4243	5262	4890	4486
SNRNP35	-7994	-7518	4093	-6	2731
SNRNP40	-791	-3141	694	7841	7635
SNRNP48	-7209	-227	225	3610	3769
SNRNP70	-7130	-7607	3062	5116	6103
SNRPA	-1672	-9302	3379	6333	864
SNRPA1	-2752	-2477	-1814	6325	7076
SNRPB	-6711	-3952	5645	4874	4918
SNRPB2	-1249	-6737	3845	3677	4178
SNRPC	-2341	-4312	-1742	8378	7966
SNRPD1	-341	-2294	5156	1350	2265
SNRPD2	-2587	-8080	5812	7972	203
SNRPD3	428	-1268	4403	8221	6276
SNRPE	-4552	-1609	2801	6300	602
SNRPG	-8824	-8240	2782	4428	6962
SNRPN	602	-4875	-871	8320	8000
SNUPN	-3301	-1695	-873	1170	3960
SNW1	-7556	-9106	4302	7224	7892
SRRM1	-1123	-3198	143	7240	4545
SRRM2	407	-1575	5878	3259	1253
SRRT	-863	-3259	-122	-999	-607
SUPT5H	-6673	-3722	2917	4179	5870
SYF2	-6245	-7645	917	6860	6924
SYMPK	-8912	-7534	4027	4534	5149
TBL3	-6351	-4910	3907	5814	1166
TEX10	-3423	-3222	3700	1160	6096
TFB1M	-8224	-5530	3453	2841	5213
TFIP11	-859	-2343	-1766	7655	5721
THADA	-4802	-1088	2397	5184	4708
THG1L	-7699	-6234	1098	3987	6499
THOC1	-6047	-2930	2712	4926	482
THOC5	-4697	-6675	-1746	6249	7452
THOC7	-8896	-7895	3898	-1303	-195
THUMPD1	-1299	-7743	-2354	7215	7293
TNFSF13	-2801	-8137	3354	367	1469
TNKS1BP1	-3932	-2513	-517	5298	1000
TNPO1	-3433	-5362	5407	2469	4010
TP53RK	-5114	-2461	-769	6464	4750
TPR	-1912	-1701	2275	6893	903
TPRKB	-1911	-9256	-1024	6271	2593
TRDMT1	-5314	-8546	5329	4922	2417
TRIT1	-3322	-8639	5230	6557	1542
TRMT1	-6604	-7138	2891	1695	3412
TRMT11	-6080	-6265	2814	2642	951
TRMT12	-7007	-6530	6460	551	7052
TRMT61A	-2430	-3898	918	1453	1126
TRMT61B	-5541	-6503	1149	3550	6751
TRMU	464	-5840	4103	7048	4738
TRNT1	-5992	-2317	5085	3712	3972
TSEN15	-718	-5357	3923	2949	1299
TSEN2	-1896	-6335	5121	-657	1122
TSEN54	-2336	17	6410	8251	5645
TSR1	-401	-7858	-615	1421	8087
TTC37	-8443	-9471	6192	4449	8396
TXNL4A	-2472	-359	3705	-98	-667
TYW1	-9049	-2558	-1008	284	-1149
TYW3	-106	-1056	-388	244	5777
U2AF1	-6388	-3920	-1258	2776	2028
U2AF1L4	-8452	-3382	6502	6821	2490
U2AF2	-269	-3015	2075	2952	1484
UBA52	-513	-1242	1530	5448	5828
UBB	-6553	-5964	-13	7418	8036
UBC	-8288	-7011	-1067	5810	7639
UPF1	-2339	26	478	3538	3027
UPF2	-4419	-6130	3206	2503	1382
UPF3A	-4731	-2250	5839	2172	4276
URM1	-8736	-7369	-1083	1362	6043
USP39	-4669	-4333	-1921	4527	5860
UTP15	-4172	-8340	2250	4993	5787
UTP20	-4309	-9369	1726	7701	8426
UTP3	-7407	-6686	4792	4201	2357
UTP6	-1554	-7039	-1982	7403	8055
WBP11	-3724	-8455	4297	6347	7147
WBP4	-7960	-8405	-1098	-845	-1183
WBSCR22	-804	-282	-787	7872	6653
WDR12	-2331	-8402	-1014	5442	8152
WDR18	-4202	-6937	-1636	7463	5776
WDR3	-3894	-2871	5316	1443	5073
WDR33	-4998	-3170	2377	1490	1142
WDR36	-4315	-1996	3648	2073	4211
WDR43	-7910	-5699	6105	5052	858
WDR61	-8482	-7359	5946	2635	-612
WDR75	-4477	-8608	3688	7541	7194
WDR77	-130	195	5761	6314	-836
WTAP	-6606	-2456	4617	3380	5010
XAB2	-8628	-6086	-396	4099	5265
XPO1	-6677	-4338	4933	4303	2828
XPOT	-3639	-950	-2331	5466	-10
XRN2	-1731	-7300	2453	2897	4923
YBX1	-5841	-1802	2033	2163	6021
YWHAB	-8399	-1843	4484	506	2768
YWHAZ	-3040	-5815	5742	5837	1734
ZBTB8OS	-7348	-1237	-2329	7434	7592
ZCCHC11	-609	224	5781	1872	3386
ZCCHC6	-3075	-8644	1333	6428	4789
ZFP36	-7923	-5874	5694	4950	199
ZFP36L1	-2702	-4194	5905	5570	6705
ZMAT5	-1025	-629	-2802	-1367	-1219

---

---

Cell Cycle

Cell Cycle

metric	value
setSize	482
pMANOVA	2.09e-06
p.adjustMANOVA	0.000946
s.dist	0.159
s.psf	-0.0683
s.psb	-0.0688
s.hcy	0.112
s.folate	0.0551
s.vitb12	0.00975
p.psf	0.0113
p.psb	0.0107
p.hcy	3.1e-05
p.folate	0.0409
p.vitb12	0.718

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	hcy	psb
PSME4	5997	-8991
HMMR	5977	-8925
NCAPD3	5898	-8818
LBR	5971	-8663
USO1	6098	-8242
INCENP	5832	-8460
SKP1	6201	-7721
CHTF8	5720	-8195
LEMD2	5022	-9314
NUP85	5526	-8224
ACTR1A	6228	-7285
STAG1	5829	-7770
RNF168	5302	-8477
TUBGCP3	6638	-6714
POM121	5593	-7922
CENPJ	5613	-7834
PSMA1	5104	-8604
NOP10	5068	-8584
PCBP4	5393	-8018
TERF2IP	5281	-8159

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
AAAS	-4813	-3658	2354	1828	2776
ABL1	-5509	-7422	-538	5899	4752
ACD	-4066	-313	3133	-1249	-913
ACTR1A	-7409	-7285	6228	2166	2934
AHCTF1	-958	-5776	-1162	5566	2735
AKAP9	-879	-2573	3852	3811	6300
AKT1	-8746	-7641	4880	-1052	2534
AKT2	-3735	-7913	-487	5440	7835
ALMS1	-1678	-5983	-1625	6835	3815
ANAPC1	-4888	-4370	4561	5142	1218
ANAPC10	-404	-8610	-361	6447	2473
ANAPC11	-1837	-244	601	4297	4855
ANAPC2	-5187	-4944	5252	-135	-940
ANAPC4	-1773	-8700	4698	4531	5293
ANAPC5	-2266	-8728	1095	6000	7040
ANAPC7	-3940	-8396	2305	7272	5608
ANKLE2	-2924	-731	-8	-905	1706
ANKRD28	-5800	-1881	-2389	-1034	290
APITD1	-7436	-4833	3086	-1142	-173
ARPP19	-3005	-9058	650	3356	2754
ATM	-8275	-7820	5395	5612	5420
ATR	-7759	-7294	5030	3018	2218
ATRIP	-2268	-2819	4019	104	1280
AURKA	-4625	-2521	4365	5906	2377
AURKB	-5215	-5327	5907	4882	2882
B9D2	-6812	-1761	3803	2128	3929
BANF1	-4278	-7582	1929	7554	3391
BARD1	-171	-2147	-100	5242	6156
BIRC5	-5343	-8595	2843	5224	6417
BLM	-7368	-4528	3040	6231	1776
BLZF1	-8234	-6978	4015	7341	7608
BRCA1	-8132	-9292	-334	7510	8255
BRCA2	-6527	-4501	1803	1727	1254
BRIP1	-22	-4540	-2180	8335	8511
BTRC	-2985	-8093	-1346	7288	8214
BUB1	-5409	-7034	-1899	3149	4435
BUB1B	-7490	-8066	1793	6952	3147
BUB3	-1044	-2492	-425	6580	5165
CC2D1B	-2209	-5632	4256	2926	244
CCNA2	-6844	-7471	3487	2247	4856
CCNB1	-8633	-4816	6272	-1067	-816
CCNB2	-6798	-5895	4682	7856	8479
CCND1	-5545	-3395	-822	127	1572
CCND2	-7304	-2451	4468	-145	828
CCND3	-3297	-3608	5056	1472	3466
CCNE1	525	-3003	-755	1514	7279
CCNE2	-3810	-2459	4526	-177	568
CCNH	-5123	-6984	5835	888	1368
CDC14A	-8777	-3149	4537	-160	5206
CDC16	-1108	-909	-2388	2815	1317
CDC20	-212	-931	-491	6613	4602
CDC23	-1180	-4858	84	8244	8117
CDC25A	-253	-3390	-1059	8103	6963
CDC25B	-6824	-2908	4768	445	-398
CDC25C	-4167	-6539	3835	6618	5507
CDC6	-2528	-686	-325	7291	6759
CDC7	-1029	-3503	6193	1605	3270
CDCA5	-1121	-417	3175	3307	5915
CDCA8	-4157	-4002	538	7190	8272
CDK1	-3517	-5019	2450	2546	7363
CDK11A	339	-5328	-2613	-215	7932
CDK11B	-7533	-225	3493	1392	1684
CDK2	-3067	-9380	1071	8170	2476
CDK4	-5104	-3263	1863	4831	3952
CDK5RAP2	28	-3076	-2525	8391	8566
CDK6	-1505	-5601	3867	3476	2214
CDK7	-1359	-7416	1957	8195	7509
CDKN1A	-1859	-8647	-682	379	-950
CDKN1B	-6280	-4166	4449	4561	3488
CDKN2A	-1603	-4829	-1553	-652	3818
CDKN2C	-1733	-6562	242	1412	5472
CDKN2D	-3062	-1885	3696	3381	6513
CDT1	467	-1752	-1667	8240	5110
CENPA	-5443	-3670	4463	-64	856
CENPE	-2106	-3196	899	5698	6188
CENPF	552	-58	5351	4636	6138
CENPH	-166	-3676	-1863	7000	5510
CENPJ	-6986	-7834	5613	6967	4084
CENPK	-7596	-7798	2332	7331	3303
CENPL	-5982	-8049	2744	3755	4081
CENPM	-3068	-1127	3488	4808	3710
CENPN	-7748	-8268	3464	2589	1857
CENPO	-4585	-5217	2243	6228	3869
CENPP	-8987	-5989	4188	-475	-375
CENPQ	-5168	-8986	788	4612	6598
CENPT	-2887	-4406	2029	313	2718
CEP135	-2407	-7278	2548	5696	6485
CEP152	-5236	-2244	1653	2324	1765
CEP164	-629	-2996	713	7069	7016
CEP192	-7456	-8329	2199	4990	2630
CEP250	-8527	-6903	4881	512	1570
CEP63	-6556	-7691	4259	2923	2119
CEP70	-8174	-6676	3663	2986	1045
CEP76	-8869	-6415	6523	-621	-937
CEP78	-4928	-7490	5013	2801	-327
CHEK1	-796	-7720	-889	7465	6419
CHEK2	-7879	-8563	-348	6076	3994
CHMP2A	-4412	-5990	3751	6470	5425
CHMP2B	-1760	-5679	1172	4483	2940
CHMP4A	-8629	-6757	3557	2746	6097
CHMP4B	35	-2199	-830	6687	7422
CHMP6	-41	-3642	638	7662	6991
CHMP7	-5810	-147	4685	1840	4961
CHTF18	-6454	-3107	-1160	-1405	3366
CHTF8	-2858	-8195	5720	3505	6893
CKAP5	-4894	-8730	4720	1363	835
CKS1B	-5510	-921	6522	4435	-962
CLASP1	-5095	-5549	1549	5253	6532
CLASP2	-5060	-3223	-1727	6396	6132
CLIP1	-5995	-5664	2164	-399	4405
CLSPN	-2500	-4167	5062	7142	6396
CSNK1D	-973	-7670	2239	1107	4901
CSNK1E	614	-3165	-729	7983	8577
CSNK2A2	-276	-6345	-188	5902	-421
CSNK2B	-8437	-8556	3108	982	975
CUL1	697	205	-2993	1565	8112
DAXX	-8213	-4941	3610	4825	1780
DBF4	-8257	-5890	5651	7986	-847
DCTN2	-3373	-6548	-2552	7412	7292
DCTN3	-8835	-5606	5566	4936	7213
DHFR	-993	-1053	5161	3033	-234
DIDO1	-6391	-7367	4058	457	909
DMC1	-5062	-1380	5130	-371	1873
DNA2	-8863	-6506	-708	341	315
DSCC1	-309	-3017	159	7752	6420
DSN1	-2102	-4234	3232	2568	3430
DYNC1H1	-4365	-3256	5029	425	786
DYNC1I2	-6567	-7070	2439	2184	2874
DYNC1LI1	-5010	-1342	2070	1660	915
DYNC1LI2	-3958	-1793	-456	881	-232
DYNLL1	-6435	-1692	4607	677	956
DYNLL2	-1210	-5926	4788	4965	6455
DYRK1A	-7841	-1276	4712	-128	1146
E2F1	-4735	-1187	2003	924	6888
E2F2	-3044	-4814	3131	3050	3652
E2F3	-2379	-4496	-1726	7813	7614
E2F4	-3761	-5759	2395	3528	2810
E2F5	-3169	-29	3107	-1175	-631
E2F6	-5115	-4808	1256	5514	6377
EML4	-3099	-4202	1602	4552	1606
ENSA	-8334	-6420	2792	6414	6693
EP300	-1930	-7100	4582	8147	5387
ESCO1	-1039	-3600	-1983	5354	8091
ESCO2	-355	-7046	2107	3838	6088
ESPL1	-5611	-8871	2600	5459	8069
EXO1	-6635	-2419	2233	1662	3753
FAM175A	-2695	-1455	3673	1566	6472
FBXL18	-2508	-6650	1835	-840	92
FBXO5	-3518	-5961	1996	6669	2722
FEN1	-7471	-4613	1554	5678	2252
FKBPL	-2321	-3229	39	5493	3759
FOXM1	-7948	-468	1373	1945	2399
FZR1	-640	-846	4578	-149	3801
GAR1	-3275	-7493	2470	7687	6649
GINS1	-4903	-7266	-595	5911	6329
GINS3	-2015	-9181	383	6036	7335
GINS4	-3193	-1437	1306	-66	-830
GMNN	-4457	-5424	809	5000	7897
GOLGA2	-1576	-9411	1523	8189	7664
GORASP2	-2555	-4804	-692	1133	3292
GSK3B	-1534	-6592	5172	5856	3113
GTSE1	-7032	-3414	4753	3073	3539
H2AFX	-2264	-828	-738	1976	3608
HAUS1	-8924	-8346	-139	-894	3039
HAUS2	-4906	-6282	1391	4934	5752
HAUS4	-2796	-8059	1165	7833	8154
HAUS5	-8	-7132	-1633	7311	8354
HAUS6	-1545	-9508	2952	8197	8029
HAUS8	-2937	180	4673	-1340	158
HDAC1	-6904	-1991	2753	283	4684
HJURP	-2147	-5572	-57	7148	6226
HMMR	-8878	-8925	5977	-469	1458
HSP90AA1	-1474	-2948	4393	938	5308
HSP90AB1	-6037	-9040	-1669	7956	8086
HSPA2	-8530	-5139	6296	1465	150
HUS1	-7212	-3420	2673	-1244	-1117
INCENP	-4410	-8460	5832	4041	3256
ITGB3BP	-1579	-8699	-2272	7906	4726
JAK2	-3030	-4467	227	8056	3329
KAT5	-7746	-4286	3717	4016	3371
KIF18A	-8597	-7811	5152	1274	-189
KIF23	-1214	-4433	2145	3872	4719
KIF2A	-1404	-1285	1265	7884	1754
KIF2C	-5335	-4400	4652	5934	7164
KNTC1	-4087	-2381	-2217	7127	5117
KPNB1	-6642	-3659	4322	363	1576
LBR	-6739	-8663	5971	1829	5800
LCMT1	-2343	-1444	1427	7665	7357
LEMD2	-7011	-9314	5022	6806	1314
LEMD3	-2955	-5799	2330	3740	7474
LIG1	360	62	-1221	-890	-350
LIN37	-6842	-8305	2309	5813	1485
LIN52	-4276	-6308	-467	8342	8531
LIN54	-3712	-3019	3438	4972	5802
LIN9	-9052	-1862	6417	-397	-673
LMNA	514	-8510	-2632	4679	3620
LMNB1	-7257	-5018	3817	4000	853
LPIN1	-5260	-5676	4157	-99	695
LPIN2	-3614	-3699	4654	1027	-843
MAD1L1	-2169	-893	4397	1233	2279
MAD2L1	-693	-4252	1421	6862	6842
MAPK1	-2717	-2873	-1146	3217	-292
MAPK3	-6889	-9407	-1492	8081	6172
MAPRE1	-6287	-7647	-1239	6750	6392
MAX	-4629	-6115	727	5739	5985
MCM10	-5253	-5899	998	3611	3944
MCM2	-6804	-5061	4651	400	-782
MCM3	-3853	-4054	2291	6890	6853
MCM4	-1538	-5997	581	6116	5742
MCM5	-1549	-452	5311	2398	781
MCM6	-2719	-5402	2421	5862	4475
MCM7	-4142	-6056	1350	2244	3177
MCM8	-4660	-4108	2389	6820	5878
MCPH1	-7453	-3876	2053	3416	6331
MDC1	-5699	-4547	4046	3093	3891
MDM2	-7427	-3880	5322	1489	4370
MDM4	-7073	-6259	4702	2640	5555
MIS12	-5040	-5098	3865	137	2565
MLH3	-6207	-2828	4962	2265	711
MNAT1	-192	-5911	5844	7743	7276
MND1	-8961	-4904	6612	-1015	1425
MSH5	-4881	-5696	2300	1708	3856
MYBL2	104	-3426	6528	7182	6078
NBN	-3696	-7848	771	7212	5058
NCAPD2	-5731	-3819	5235	3412	6939
NCAPD3	-7289	-8818	5898	26	1663
NCAPG	-8251	-3881	2538	-1161	485
NCAPG2	-5001	-6097	5943	628	600
NCAPH	-8054	-3153	3362	5021	2924
NCAPH2	-3174	-5947	2787	1293	-969
NDC80	-7727	-3732	4054	3903	88
NDE1	-7104	-8550	191	5467	7621
NDEL1	-3675	-1775	5672	-63	2872
NEDD1	-3862	-288	6562	-1432	-923
NEK2	-5853	-6431	2954	4274	552
NEK6	-781	-879	-68	5548	-532
NEK7	-8404	-8016	4859	4892	5614
NEK9	-3776	-2283	4727	2679	471
NHP2	-6903	-5797	4423	301	373
NIPBL	-5701	-8674	4140	2415	-14
NME7	-5566	-6971	2648	6559	7203
NOP10	-1349	-8584	5068	5553	7616
NSL1	-7171	-7994	4556	6255	5553
NUDC	-5765	-4788	5046	1526	3072
NUF2	-4503	-7059	-2397	6976	4190
NUMA1	-687	-3103	-2615	-524	5695
NUP107	-2367	-5920	902	8020	7981
NUP133	-2192	-6208	-1034	6710	4350
NUP153	-4611	-8419	2123	1709	5952
NUP155	-938	-2261	778	3101	6606
NUP160	-4062	-2126	-1133	5658	7516
NUP188	-4111	-2994	3510	3714	3909
NUP205	-8245	-8394	4686	6267	6798
NUP210	-8192	-8465	2605	2001	-159
NUP214	-3272	-1704	2474	2228	1116
NUP35	-1551	-7219	-1373	8140	8243
NUP37	-7550	-421	4573	1438	1480
NUP43	-5408	-4131	4558	2582	2522
NUP50	-4714	-688	2999	1921	1935
NUP54	-1931	-4958	3515	3754	3208
NUP62	-1453	-8038	1978	7023	5407
NUP85	-7303	-8224	5526	3668	1520
NUP93	-3267	-3790	-2168	3175	6994
NUP98	-8199	-889	2149	7764	7066
ODF2	-7755	-1603	5376	-1003	-707
OIP5	-7019	187	223	4731	3684
OPTN	-8104	-6454	5114	1035	130
PAFAH1B1	-5211	-2836	5904	687	-129
PCBP4	-3876	-8018	5393	-198	4749
PCM1	-1756	-7343	4253	6955	7282
PCNA	-6011	-2914	1160	5682	4824
PCNT	-1548	-9147	-1852	7093	4977
PDS5A	-8750	-3459	6341	166	2013
PDS5B	-8826	-3671	4713	-583	3187
PHF20	-4437	-3001	-258	4459	3014
PHLDA1	-7579	-7562	-2341	5921	4423
PIAS4	-6294	-3353	5457	2516	-643
PIF1	-2656	-762	4076	6459	6881
PKMYT1	-4169	-2770	-825	4841	2226
PLK1	-4551	-1935	-118	2868	3399
PLK4	-1681	-3910	1944	5138	4393
PMF1	-8472	-8813	4661	3508	5960
POLA2	-3726	-2000	3753	796	4909
POLD1	-8666	-5985	6147	3282	1806
POLD2	-4940	-6161	-1045	3447	2832
POLD3	-5971	-8413	2184	3919	4448
POLD4	-4890	-5258	3890	3966	-215
POLE	290	-525	-1862	-60	2007
POLE2	-6018	-9031	2292	2323	6173
POLE3	-8595	-6568	6048	3893	5164
POLE4	-4193	-7096	682	2155	-63
POLR2A	-8657	-6301	3361	1117	-706
POLR2B	-2551	-7510	1297	5291	7059
POLR2C	-375	-2722	2661	3775	1272
POLR2D	-4623	-6633	1251	-240	862
POLR2E	-7280	-5905	1641	2768	1465
POLR2F	-2647	22	2490	337	2732
POLR2G	-3892	-6713	3633	6708	4000
POLR2H	-3216	-2022	5045	1005	994
POLR2I	-6360	-3343	1067	691	4207
POLR2K	-6692	-9353	-599	7535	6282
POM121	-6127	-7922	5593	4069	6325
POM121C	-3786	-5219	3938	5072	3069
PPME1	-6569	-2868	2989	5385	4482
PPP1CB	-3739	154	-558	4935	2792
PPP1CC	383	-760	-109	3143	1760
PPP1R12A	-8727	-6921	6142	1501	5136
PPP1R12B	-7166	-3002	3352	499	-331
PPP2CA	-4081	-3471	4425	2847	2701
PPP2CB	-1353	77	5390	-624	-872
PPP2R1B	-1840	-3560	3568	7877	5301
PPP2R2A	-144	-5849	1125	5472	6709
PPP2R5A	-7527	-7188	1532	3085	360
PPP2R5B	-4467	-4603	1078	4371	2363
PPP2R5C	-3793	-9136	3153	2104	6783
PPP2R5D	-2176	-6920	-2111	6390	7682
PPP2R5E	-551	-1739	863	6882	7627
PPP6C	-7439	-2616	5865	2618	-773
PRIM1	-8477	-4168	5893	2255	6315
PRIM2	-545	-7679	4469	6939	7940
PRKACA	-4718	-4025	-1287	480	3795
PRKCA	-5820	-4955	3971	3486	5016
PRKCB	-8182	-7652	5627	-1153	-988
PSMA1	-8359	-8604	5104	1855	4650
PSMA2	-7938	-2161	5110	1432	8018
PSMA3	-2004	-4530	4184	8188	7955
PSMA5	-3753	-5163	4135	7049	6792
PSMA6	-5756	-9052	230	3273	5895
PSMA7	-5963	-1772	3526	2927	3736
PSMB1	-2258	-1758	1218	4974	2620
PSMB10	-1663	-6710	-165	6829	6594
PSMB3	-3839	-6905	4780	5497	4412
PSMB5	-89	-6668	-1101	7598	7952
PSMB6	-6634	-5888	2326	6558	5006
PSMB7	-5105	-6476	-481	6667	7933
PSMB8	-7792	-3686	5160	756	1587
PSMB9	-8032	-7032	4898	3199	1447
PSMC1	89	-6196	611	7227	6270
PSMC3	-4234	-5168	-1757	3247	5525
PSMC3IP	-7094	-7398	2386	3341	1309
PSMC4	-5962	-6708	1563	2130	2138
PSMC5	-7766	-7267	5418	2470	428
PSMC6	-7087	-7964	4301	5996	2878
PSMD1	-1790	-8089	458	4661	6182
PSMD11	-1272	-2207	4285	6544	4390
PSMD12	-2535	-3717	20	7015	7973
PSMD13	-8546	-5774	4927	2662	-882
PSMD14	-2548	-5579	3518	3709	4574
PSMD2	-7305	-6402	3485	3621	4835
PSMD3	-6151	-6416	5506	2545	2496
PSMD4	-7964	-5567	754	5325	7149
PSMD6	-4518	-717	1908	2403	114
PSMD7	-3120	-8646	2963	5075	5520
PSMD8	-4369	-5263	1397	3011	5309
PSMD9	-1075	-5374	3215	4605	1840
PSME1	-4828	-2498	2379	209	820
PSME2	-3988	-5227	2344	6844	5159
PSME3	-502	-1677	210	3994	6092
PSME4	-4990	-8991	5997	207	-839
PSMF1	-490	-5529	-2618	4670	8624
PTTG1	-6300	-7345	144	7353	5706
RAB1A	-6184	-6579	5660	3203	2130
RAB1B	-2863	-5525	2090	5130	4433
RAB2A	-7010	-5090	4608	961	2595
RAB8A	-1364	-5944	2929	5198	5223
RAD1	-2010	-5463	2568	5463	3558
RAD17	-5145	-7634	5216	4128	544
RAD21	-6823	-6698	-54	7352	7315
RAD50	-2315	-2352	2399	2091	556
RAD51	-7017	-3331	4554	-439	-141
RAD9A	-946	-6495	2307	4718	3770
RAD9B	-1124	-1031	-903	2039	6506
RAE1	-8303	-1469	2950	2287	4628
RAN	215	-1000	-1174	7323	7330
RANBP2	-3530	-4429	-1283	4903	6045
RANGAP1	-1482	-1294	-174	7332	7247
RB1	-3440	-7436	2475	4145	2659
RBBP4	-1926	-4404	290	4089	6722
RBBP8	-6815	-5097	3582	5688	3497
RBL1	-6193	-4270	5755	2357	-724
RBL2	-6440	-6455	1390	3212	5306
RBX1	-8553	-7492	5617	651	240
RCC1	-8899	-1220	6472	4803	-1137
RCC2	-4789	-1909	3142	1194	346
REC8	-6418	-8828	-3078	113	265
RFC2	-4804	-2926	-1443	1616	1319
RFC3	-7308	-5104	4829	3107	6361
RFC4	-690	-6860	3851	5818	3875
RFC5	-8100	-6481	5700	-452	-358
RFWD2	-7675	-1640	6115	2105	1541
RNF168	-6893	-8477	5302	1539	3812
RNF8	-5539	-7078	-345	3398	5805
RPA1	-4921	-4495	1606	6872	2672
RPA3	-7347	-4983	4462	6870	6874
RPS27A	-6317	-9335	373	8228	8264
RRM2	-2598	-3366	-786	3344	1628
RSF1	-402	-8033	-1349	6513	5052
RTEL1	-3758	-2757	-1540	913	4741
RUVBL1	-8888	-6605	4056	5146	2676
RUVBL2	-5783	-3028	-1068	7864	2591
SDCCAG8	-4645	-2484	4907	4864	2284
SEC13	-8747	-6731	4873	-516	1432
SEH1L	-7723	-5493	4691	844	4470
SET	-7638	-9528	-2876	7004	5720
SFN	-1185	-5538	-2958	2563	8491
SHQ1	-2872	-8127	3844	4245	5424
SIRT2	-3680	-1049	5840	3829	3363
SKA2	-9013	-5218	2224	8095	7700
SKP1	-1797	-7721	6201	2774	2018
SKP2	-1150	-8814	-743	7917	8093
SMARCA5	-1416	-6020	184	6934	5730
SMC1B	59	-1933	2336	7653	3325
SMC2	-9011	-8483	1629	6410	2042
SMC3	-5441	-8998	4416	6498	3310
SMC4	-8756	-6272	4224	-1396	-1099
SPAST	-7900	-8245	4541	1651	2766
SPC24	-4560	-3857	1317	4230	1955
SPC25	-2804	-6663	-1447	8021	7791
SRC	-5098	-8229	-427	-41	-814
STAG1	-6618	-7770	5829	5087	5078
STAG3	-602	-3176	396	3988	7093
STRA13	-5207	-5602	-275	-841	3077
SUMO1	-1344	-2879	-2075	6159	7290
SYCE2	-3804	-8566	-376	1032	56
SYNE1	-5395	-6137	-1586	5577	7536
SYNE2	-2131	-9383	3284	1290	1924
TAOK1	-5074	-852	6421	1847	383
TERF1	-4657	-5906	936	5088	3646
TERF2	-8117	-8978	1787	2541	1152
TERF2IP	-3819	-8159	5281	1951	676
TERT	-2529	-182	6752	-1200	-1169
TFDP1	191	-2894	-2589	638	513
TINF2	-8428	-6625	5012	-23	-8
TK1	-4647	-6204	1054	4957	5139
TMPO	-1	-178	629	4115	1507
TNPO1	-3433	-5362	5407	2469	4010
TOP2A	-5361	-7888	803	8006	6217
TOP3A	-5942	-8744	1914	4426	5926
TOPBP1	-1673	-2481	-548	4387	1153
TP53	-3124	-9254	3539	7152	6754
TP53BP1	-3674	-4932	673	6576	6545
TPR	-1912	-1701	2275	6893	903
TPX2	-3260	-8888	313	8220	8229
TUBA1A	-3868	-6814	281	7982	5851
TUBA1B	-2586	-3957	1859	3184	4585
TUBA1C	-3611	-1926	3980	5273	1821
TUBA4A	-2725	-3627	757	7569	1248
TUBA4B	-8730	-3132	6556	-578	-182
TUBB	-6989	-2735	6157	-695	73
TUBB2A	-1141	-1970	-2479	3793	3564
TUBG2	-6985	-7753	1108	3397	4830
TUBGCP2	-8572	-9202	3059	-1079	125
TUBGCP3	-8505	-6714	6638	-52	4915
TUBGCP5	399	79	-2707	8176	1722
TUBGCP6	-8332	-6185	6580	-1186	-842
TYMS	-8254	-4386	2982	2436	802
UBA52	-513	-1242	1530	5448	5828
UBB	-6553	-5964	-13	7418	8036
UBC	-8288	-7011	-1067	5810	7639
UBE2C	-759	-2829	-1688	6275	6660
UBE2D1	-2809	-3007	-157	1866	1336
UBE2E1	-4493	-4384	-1323	3040	2903
UBE2I	-3937	-1487	5265	-28	148
UBE2N	-8194	-8856	-1821	-825	-1145
UBE2V2	-7680	-3487	3079	-616	-361
USO1	-8493	-8242	6098	1982	4249
VPS4A	-3975	-2950	2335	4622	5426
VRK1	-4206	-3102	4985	6441	4404
VRK2	-2498	-7336	-1683	8002	7219
WEE1	-6170	-447	3951	633	2639
WRAP53	-7202	-7942	3872	4639	2800
WRN	-7185	-2945	3981	-1274	860
XPO1	-6677	-4338	4933	4303	2828
YWHAB	-8399	-1843	4484	506	2768
YWHAE	138	-1017	-2211	1240	4019
YWHAG	-2464	-4668	3556	3296	1364
YWHAH	-6022	-342	3424	986	3546
YWHAQ	-6396	-1086	696	181	1519
YWHAZ	-3040	-5815	5742	5837	1734
ZW10	-3358	-4465	-133	4675	7777
ZWILCH	-1670	-8800	-1593	8324	8308
ZWINT	-4132	-4213	2506	5868	2166

---

---

Cell Cycle, Mitotic

Cell Cycle, Mitotic

metric	value
setSize	390
pMANOVA	3.1e-06
p.adjustMANOVA	0.000946
s.dist	0.166
s.psf	-0.0472
s.psb	-0.0686
s.hcy	0.108
s.folate	0.0865
s.vitb12	0.0371
p.psf	0.114
p.psb	0.0215
p.hcy	0.000277
p.folate	0.00371
p.vitb12	0.214

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	hcy	folate
MYBL2	6528	7182
MNAT1	5844	7743
DBF4	5651	7986
CENPJ	5613	6967
EP300	4582	8147
CCNB2	4682	7856
PSMA3	4184	8188
LEMD2	5022	6806
VRK1	4985	6441
RCC1	6472	4803
PRIM2	4469	6939
RPA3	4462	6870
GSK3B	5172	5856
STAG1	5829	5087
PCM1	4253	6955
BLZF1	4015	7341
NUP205	4686	6267
PSMA5	4135	7049
CKS1B	6522	4435
AURKB	5907	4882

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
AAAS	-4813	-3658	2354	1828	2776
ABL1	-5509	-7422	-538	5899	4752
ACTR1A	-7409	-7285	6228	2166	2934
AHCTF1	-958	-5776	-1162	5566	2735
AKAP9	-879	-2573	3852	3811	6300
AKT1	-8746	-7641	4880	-1052	2534
AKT2	-3735	-7913	-487	5440	7835
ALMS1	-1678	-5983	-1625	6835	3815
ANAPC1	-4888	-4370	4561	5142	1218
ANAPC10	-404	-8610	-361	6447	2473
ANAPC11	-1837	-244	601	4297	4855
ANAPC2	-5187	-4944	5252	-135	-940
ANAPC4	-1773	-8700	4698	4531	5293
ANAPC5	-2266	-8728	1095	6000	7040
ANAPC7	-3940	-8396	2305	7272	5608
ANKLE2	-2924	-731	-8	-905	1706
APITD1	-7436	-4833	3086	-1142	-173
ARPP19	-3005	-9058	650	3356	2754
AURKA	-4625	-2521	4365	5906	2377
AURKB	-5215	-5327	5907	4882	2882
B9D2	-6812	-1761	3803	2128	3929
BANF1	-4278	-7582	1929	7554	3391
BIRC5	-5343	-8595	2843	5224	6417
BLZF1	-8234	-6978	4015	7341	7608
BTRC	-2985	-8093	-1346	7288	8214
BUB1	-5409	-7034	-1899	3149	4435
BUB1B	-7490	-8066	1793	6952	3147
BUB3	-1044	-2492	-425	6580	5165
CC2D1B	-2209	-5632	4256	2926	244
CCNA2	-6844	-7471	3487	2247	4856
CCNB1	-8633	-4816	6272	-1067	-816
CCNB2	-6798	-5895	4682	7856	8479
CCND1	-5545	-3395	-822	127	1572
CCND2	-7304	-2451	4468	-145	828
CCND3	-3297	-3608	5056	1472	3466
CCNE1	525	-3003	-755	1514	7279
CCNE2	-3810	-2459	4526	-177	568
CCNH	-5123	-6984	5835	888	1368
CDC14A	-8777	-3149	4537	-160	5206
CDC16	-1108	-909	-2388	2815	1317
CDC20	-212	-931	-491	6613	4602
CDC23	-1180	-4858	84	8244	8117
CDC25A	-253	-3390	-1059	8103	6963
CDC25B	-6824	-2908	4768	445	-398
CDC25C	-4167	-6539	3835	6618	5507
CDC6	-2528	-686	-325	7291	6759
CDC7	-1029	-3503	6193	1605	3270
CDCA5	-1121	-417	3175	3307	5915
CDCA8	-4157	-4002	538	7190	8272
CDK1	-3517	-5019	2450	2546	7363
CDK11A	339	-5328	-2613	-215	7932
CDK11B	-7533	-225	3493	1392	1684
CDK2	-3067	-9380	1071	8170	2476
CDK4	-5104	-3263	1863	4831	3952
CDK5RAP2	28	-3076	-2525	8391	8566
CDK6	-1505	-5601	3867	3476	2214
CDK7	-1359	-7416	1957	8195	7509
CDKN1A	-1859	-8647	-682	379	-950
CDKN1B	-6280	-4166	4449	4561	3488
CDKN2A	-1603	-4829	-1553	-652	3818
CDKN2C	-1733	-6562	242	1412	5472
CDKN2D	-3062	-1885	3696	3381	6513
CDT1	467	-1752	-1667	8240	5110
CENPA	-5443	-3670	4463	-64	856
CENPE	-2106	-3196	899	5698	6188
CENPF	552	-58	5351	4636	6138
CENPH	-166	-3676	-1863	7000	5510
CENPJ	-6986	-7834	5613	6967	4084
CENPK	-7596	-7798	2332	7331	3303
CENPL	-5982	-8049	2744	3755	4081
CENPM	-3068	-1127	3488	4808	3710
CENPN	-7748	-8268	3464	2589	1857
CENPO	-4585	-5217	2243	6228	3869
CENPP	-8987	-5989	4188	-475	-375
CENPQ	-5168	-8986	788	4612	6598
CENPT	-2887	-4406	2029	313	2718
CEP135	-2407	-7278	2548	5696	6485
CEP152	-5236	-2244	1653	2324	1765
CEP164	-629	-2996	713	7069	7016
CEP192	-7456	-8329	2199	4990	2630
CEP250	-8527	-6903	4881	512	1570
CEP63	-6556	-7691	4259	2923	2119
CEP70	-8174	-6676	3663	2986	1045
CEP76	-8869	-6415	6523	-621	-937
CEP78	-4928	-7490	5013	2801	-327
CHMP2A	-4412	-5990	3751	6470	5425
CHMP2B	-1760	-5679	1172	4483	2940
CHMP4A	-8629	-6757	3557	2746	6097
CHMP4B	35	-2199	-830	6687	7422
CHMP6	-41	-3642	638	7662	6991
CHMP7	-5810	-147	4685	1840	4961
CKAP5	-4894	-8730	4720	1363	835
CKS1B	-5510	-921	6522	4435	-962
CLASP1	-5095	-5549	1549	5253	6532
CLASP2	-5060	-3223	-1727	6396	6132
CLIP1	-5995	-5664	2164	-399	4405
CSNK1D	-973	-7670	2239	1107	4901
CSNK1E	614	-3165	-729	7983	8577
CSNK2A2	-276	-6345	-188	5902	-421
CSNK2B	-8437	-8556	3108	982	975
CUL1	697	205	-2993	1565	8112
DBF4	-8257	-5890	5651	7986	-847
DCTN2	-3373	-6548	-2552	7412	7292
DCTN3	-8835	-5606	5566	4936	7213
DHFR	-993	-1053	5161	3033	-234
DNA2	-8863	-6506	-708	341	315
DSN1	-2102	-4234	3232	2568	3430
DYNC1H1	-4365	-3256	5029	425	786
DYNC1I2	-6567	-7070	2439	2184	2874
DYNC1LI1	-5010	-1342	2070	1660	915
DYNC1LI2	-3958	-1793	-456	881	-232
DYNLL1	-6435	-1692	4607	677	956
DYNLL2	-1210	-5926	4788	4965	6455
DYRK1A	-7841	-1276	4712	-128	1146
E2F1	-4735	-1187	2003	924	6888
E2F2	-3044	-4814	3131	3050	3652
E2F3	-2379	-4496	-1726	7813	7614
E2F4	-3761	-5759	2395	3528	2810
E2F5	-3169	-29	3107	-1175	-631
E2F6	-5115	-4808	1256	5514	6377
EML4	-3099	-4202	1602	4552	1606
ENSA	-8334	-6420	2792	6414	6693
EP300	-1930	-7100	4582	8147	5387
ESCO1	-1039	-3600	-1983	5354	8091
ESCO2	-355	-7046	2107	3838	6088
ESPL1	-5611	-8871	2600	5459	8069
FBXL18	-2508	-6650	1835	-840	92
FBXO5	-3518	-5961	1996	6669	2722
FEN1	-7471	-4613	1554	5678	2252
FKBPL	-2321	-3229	39	5493	3759
FOXM1	-7948	-468	1373	1945	2399
FZR1	-640	-846	4578	-149	3801
GINS1	-4903	-7266	-595	5911	6329
GINS3	-2015	-9181	383	6036	7335
GINS4	-3193	-1437	1306	-66	-830
GMNN	-4457	-5424	809	5000	7897
GOLGA2	-1576	-9411	1523	8189	7664
GORASP2	-2555	-4804	-692	1133	3292
GSK3B	-1534	-6592	5172	5856	3113
GTSE1	-7032	-3414	4753	3073	3539
H2AFX	-2264	-828	-738	1976	3608
HAUS1	-8924	-8346	-139	-894	3039
HAUS2	-4906	-6282	1391	4934	5752
HAUS4	-2796	-8059	1165	7833	8154
HAUS5	-8	-7132	-1633	7311	8354
HAUS6	-1545	-9508	2952	8197	8029
HAUS8	-2937	180	4673	-1340	158
HDAC1	-6904	-1991	2753	283	4684
HMMR	-8878	-8925	5977	-469	1458
HSP90AA1	-1474	-2948	4393	938	5308
HSP90AB1	-6037	-9040	-1669	7956	8086
INCENP	-4410	-8460	5832	4041	3256
ITGB3BP	-1579	-8699	-2272	7906	4726
JAK2	-3030	-4467	227	8056	3329
KIF18A	-8597	-7811	5152	1274	-189
KIF23	-1214	-4433	2145	3872	4719
KIF2A	-1404	-1285	1265	7884	1754
KIF2C	-5335	-4400	4652	5934	7164
KNTC1	-4087	-2381	-2217	7127	5117
KPNB1	-6642	-3659	4322	363	1576
LBR	-6739	-8663	5971	1829	5800
LCMT1	-2343	-1444	1427	7665	7357
LEMD2	-7011	-9314	5022	6806	1314
LEMD3	-2955	-5799	2330	3740	7474
LIG1	360	62	-1221	-890	-350
LIN37	-6842	-8305	2309	5813	1485
LIN52	-4276	-6308	-467	8342	8531
LIN54	-3712	-3019	3438	4972	5802
LIN9	-9052	-1862	6417	-397	-673
LMNA	514	-8510	-2632	4679	3620
LMNB1	-7257	-5018	3817	4000	853
LPIN1	-5260	-5676	4157	-99	695
LPIN2	-3614	-3699	4654	1027	-843
MAD1L1	-2169	-893	4397	1233	2279
MAD2L1	-693	-4252	1421	6862	6842
MAPK1	-2717	-2873	-1146	3217	-292
MAPK3	-6889	-9407	-1492	8081	6172
MAPRE1	-6287	-7647	-1239	6750	6392
MAX	-4629	-6115	727	5739	5985
MCM10	-5253	-5899	998	3611	3944
MCM2	-6804	-5061	4651	400	-782
MCM3	-3853	-4054	2291	6890	6853
MCM4	-1538	-5997	581	6116	5742
MCM5	-1549	-452	5311	2398	781
MCM6	-2719	-5402	2421	5862	4475
MCM7	-4142	-6056	1350	2244	3177
MCM8	-4660	-4108	2389	6820	5878
MCPH1	-7453	-3876	2053	3416	6331
MIS12	-5040	-5098	3865	137	2565
MNAT1	-192	-5911	5844	7743	7276
MYBL2	104	-3426	6528	7182	6078
NCAPD2	-5731	-3819	5235	3412	6939
NCAPD3	-7289	-8818	5898	26	1663
NCAPG	-8251	-3881	2538	-1161	485
NCAPG2	-5001	-6097	5943	628	600
NCAPH	-8054	-3153	3362	5021	2924
NCAPH2	-3174	-5947	2787	1293	-969
NDC80	-7727	-3732	4054	3903	88
NDE1	-7104	-8550	191	5467	7621
NDEL1	-3675	-1775	5672	-63	2872
NEDD1	-3862	-288	6562	-1432	-923
NEK2	-5853	-6431	2954	4274	552
NEK6	-781	-879	-68	5548	-532
NEK7	-8404	-8016	4859	4892	5614
NEK9	-3776	-2283	4727	2679	471
NIPBL	-5701	-8674	4140	2415	-14
NME7	-5566	-6971	2648	6559	7203
NSL1	-7171	-7994	4556	6255	5553
NUDC	-5765	-4788	5046	1526	3072
NUF2	-4503	-7059	-2397	6976	4190
NUMA1	-687	-3103	-2615	-524	5695
NUP107	-2367	-5920	902	8020	7981
NUP133	-2192	-6208	-1034	6710	4350
NUP153	-4611	-8419	2123	1709	5952
NUP155	-938	-2261	778	3101	6606
NUP160	-4062	-2126	-1133	5658	7516
NUP188	-4111	-2994	3510	3714	3909
NUP205	-8245	-8394	4686	6267	6798
NUP210	-8192	-8465	2605	2001	-159
NUP214	-3272	-1704	2474	2228	1116
NUP35	-1551	-7219	-1373	8140	8243
NUP37	-7550	-421	4573	1438	1480
NUP43	-5408	-4131	4558	2582	2522
NUP50	-4714	-688	2999	1921	1935
NUP54	-1931	-4958	3515	3754	3208
NUP62	-1453	-8038	1978	7023	5407
NUP85	-7303	-8224	5526	3668	1520
NUP93	-3267	-3790	-2168	3175	6994
NUP98	-8199	-889	2149	7764	7066
ODF2	-7755	-1603	5376	-1003	-707
OPTN	-8104	-6454	5114	1035	130
PAFAH1B1	-5211	-2836	5904	687	-129
PCM1	-1756	-7343	4253	6955	7282
PCNA	-6011	-2914	1160	5682	4824
PCNT	-1548	-9147	-1852	7093	4977
PDS5A	-8750	-3459	6341	166	2013
PDS5B	-8826	-3671	4713	-583	3187
PHLDA1	-7579	-7562	-2341	5921	4423
PKMYT1	-4169	-2770	-825	4841	2226
PLK1	-4551	-1935	-118	2868	3399
PLK4	-1681	-3910	1944	5138	4393
PMF1	-8472	-8813	4661	3508	5960
POLA2	-3726	-2000	3753	796	4909
POLD1	-8666	-5985	6147	3282	1806
POLD2	-4940	-6161	-1045	3447	2832
POLD3	-5971	-8413	2184	3919	4448
POLD4	-4890	-5258	3890	3966	-215
POLE	290	-525	-1862	-60	2007
POLE2	-6018	-9031	2292	2323	6173
POLE3	-8595	-6568	6048	3893	5164
POLE4	-4193	-7096	682	2155	-63
POM121	-6127	-7922	5593	4069	6325
POM121C	-3786	-5219	3938	5072	3069
PPME1	-6569	-2868	2989	5385	4482
PPP1CB	-3739	154	-558	4935	2792
PPP1CC	383	-760	-109	3143	1760
PPP1R12A	-8727	-6921	6142	1501	5136
PPP1R12B	-7166	-3002	3352	499	-331
PPP2CA	-4081	-3471	4425	2847	2701
PPP2CB	-1353	77	5390	-624	-872
PPP2R1B	-1840	-3560	3568	7877	5301
PPP2R2A	-144	-5849	1125	5472	6709
PPP2R5A	-7527	-7188	1532	3085	360
PPP2R5B	-4467	-4603	1078	4371	2363
PPP2R5C	-3793	-9136	3153	2104	6783
PPP2R5D	-2176	-6920	-2111	6390	7682
PPP2R5E	-551	-1739	863	6882	7627
PRIM1	-8477	-4168	5893	2255	6315
PRIM2	-545	-7679	4469	6939	7940
PRKACA	-4718	-4025	-1287	480	3795
PRKCA	-5820	-4955	3971	3486	5016
PRKCB	-8182	-7652	5627	-1153	-988
PSMA1	-8359	-8604	5104	1855	4650
PSMA2	-7938	-2161	5110	1432	8018
PSMA3	-2004	-4530	4184	8188	7955
PSMA5	-3753	-5163	4135	7049	6792
PSMA6	-5756	-9052	230	3273	5895
PSMA7	-5963	-1772	3526	2927	3736
PSMB1	-2258	-1758	1218	4974	2620
PSMB10	-1663	-6710	-165	6829	6594
PSMB3	-3839	-6905	4780	5497	4412
PSMB5	-89	-6668	-1101	7598	7952
PSMB6	-6634	-5888	2326	6558	5006
PSMB7	-5105	-6476	-481	6667	7933
PSMB8	-7792	-3686	5160	756	1587
PSMB9	-8032	-7032	4898	3199	1447
PSMC1	89	-6196	611	7227	6270
PSMC3	-4234	-5168	-1757	3247	5525
PSMC4	-5962	-6708	1563	2130	2138
PSMC5	-7766	-7267	5418	2470	428
PSMC6	-7087	-7964	4301	5996	2878
PSMD1	-1790	-8089	458	4661	6182
PSMD11	-1272	-2207	4285	6544	4390
PSMD12	-2535	-3717	20	7015	7973
PSMD13	-8546	-5774	4927	2662	-882
PSMD14	-2548	-5579	3518	3709	4574
PSMD2	-7305	-6402	3485	3621	4835
PSMD3	-6151	-6416	5506	2545	2496
PSMD4	-7964	-5567	754	5325	7149
PSMD6	-4518	-717	1908	2403	114
PSMD7	-3120	-8646	2963	5075	5520
PSMD8	-4369	-5263	1397	3011	5309
PSMD9	-1075	-5374	3215	4605	1840
PSME1	-4828	-2498	2379	209	820
PSME2	-3988	-5227	2344	6844	5159
PSME3	-502	-1677	210	3994	6092
PSME4	-4990	-8991	5997	207	-839
PSMF1	-490	-5529	-2618	4670	8624
PTTG1	-6300	-7345	144	7353	5706
RAB1A	-6184	-6579	5660	3203	2130
RAB1B	-2863	-5525	2090	5130	4433
RAB2A	-7010	-5090	4608	961	2595
RAB8A	-1364	-5944	2929	5198	5223
RAD21	-6823	-6698	-54	7352	7315
RAE1	-8303	-1469	2950	2287	4628
RAN	215	-1000	-1174	7323	7330
RANBP2	-3530	-4429	-1283	4903	6045
RANGAP1	-1482	-1294	-174	7332	7247
RB1	-3440	-7436	2475	4145	2659
RBBP4	-1926	-4404	290	4089	6722
RBL1	-6193	-4270	5755	2357	-724
RBL2	-6440	-6455	1390	3212	5306
RBX1	-8553	-7492	5617	651	240
RCC1	-8899	-1220	6472	4803	-1137
RCC2	-4789	-1909	3142	1194	346
RFC2	-4804	-2926	-1443	1616	1319
RFC3	-7308	-5104	4829	3107	6361
RFC4	-690	-6860	3851	5818	3875
RFC5	-8100	-6481	5700	-452	-358
RPA1	-4921	-4495	1606	6872	2672
RPA3	-7347	-4983	4462	6870	6874
RPS27A	-6317	-9335	373	8228	8264
RRM2	-2598	-3366	-786	3344	1628
SDCCAG8	-4645	-2484	4907	4864	2284
SEC13	-8747	-6731	4873	-516	1432
SEH1L	-7723	-5493	4691	844	4470
SET	-7638	-9528	-2876	7004	5720
SIRT2	-3680	-1049	5840	3829	3363
SKA2	-9013	-5218	2224	8095	7700
SKP1	-1797	-7721	6201	2774	2018
SKP2	-1150	-8814	-743	7917	8093
SMC2	-9011	-8483	1629	6410	2042
SMC3	-5441	-8998	4416	6498	3310
SMC4	-8756	-6272	4224	-1396	-1099
SPAST	-7900	-8245	4541	1651	2766
SPC24	-4560	-3857	1317	4230	1955
SPC25	-2804	-6663	-1447	8021	7791
SRC	-5098	-8229	-427	-41	-814
STAG1	-6618	-7770	5829	5087	5078
SUMO1	-1344	-2879	-2075	6159	7290
TAOK1	-5074	-852	6421	1847	383
TFDP1	191	-2894	-2589	638	513
TK1	-4647	-6204	1054	4957	5139
TMPO	-1	-178	629	4115	1507
TNPO1	-3433	-5362	5407	2469	4010
TOP2A	-5361	-7888	803	8006	6217
TP53	-3124	-9254	3539	7152	6754
TPR	-1912	-1701	2275	6893	903
TPX2	-3260	-8888	313	8220	8229
TUBA1A	-3868	-6814	281	7982	5851
TUBA1B	-2586	-3957	1859	3184	4585
TUBA1C	-3611	-1926	3980	5273	1821
TUBA4A	-2725	-3627	757	7569	1248
TUBA4B	-8730	-3132	6556	-578	-182
TUBB	-6989	-2735	6157	-695	73
TUBB2A	-1141	-1970	-2479	3793	3564
TUBG2	-6985	-7753	1108	3397	4830
TUBGCP2	-8572	-9202	3059	-1079	125
TUBGCP3	-8505	-6714	6638	-52	4915
TUBGCP5	399	79	-2707	8176	1722
TUBGCP6	-8332	-6185	6580	-1186	-842
TYMS	-8254	-4386	2982	2436	802
UBA52	-513	-1242	1530	5448	5828
UBB	-6553	-5964	-13	7418	8036
UBC	-8288	-7011	-1067	5810	7639
UBE2C	-759	-2829	-1688	6275	6660
UBE2D1	-2809	-3007	-157	1866	1336
UBE2E1	-4493	-4384	-1323	3040	2903
UBE2I	-3937	-1487	5265	-28	148
USO1	-8493	-8242	6098	1982	4249
VPS4A	-3975	-2950	2335	4622	5426
VRK1	-4206	-3102	4985	6441	4404
VRK2	-2498	-7336	-1683	8002	7219
WEE1	-6170	-447	3951	633	2639
XPO1	-6677	-4338	4933	4303	2828
YWHAE	138	-1017	-2211	1240	4019
YWHAG	-2464	-4668	3556	3296	1364
ZW10	-3358	-4465	-133	4675	7777
ZWILCH	-1670	-8800	-1593	8324	8308
ZWINT	-4132	-4213	2506	5868	2166

---

---

Regulation of expression of SLITs and ROBOs

Regulation of expression of SLITs and ROBOs

metric	value
setSize	117
pMANOVA	3.32e-06
p.adjustMANOVA	0.000946
s.dist	0.306
s.psf	0.0325
s.psb	-0.12
s.hcy	0.136
s.folate	0.188
s.vitb12	0.156
p.psf	0.545
p.psb	0.0253
p.hcy	0.0113
p.folate	0.000473
p.vitb12	0.0036

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
NCBP1	8402	8509
RPS27A	8228	8264
RPS24	7985	8504
RPSA	8071	8168
RPL15	7772	8423
RPL34	7954	8213
PSMA3	8188	7955
RPS25	8288	7689
RPL28	7634	8337
RPL9	7462	8503
RPS28	8167	7739
PSMB5	7598	7952
UBB	7418	8036
RPL41	7287	7829
RPS6	8168	6880
PSMD12	7015	7973
RPL32	6861	8038
RPL37A	6591	8046
PSMB7	6667	7933
RPS16	6351	8153

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
CASC3	-5894	-3543	-120	2750	7789
CUL2	-6279	-4347	4648	4094	359
DAG1	-5529	-8643	-1037	1109	-387
EIF4A3	-1889	-241	4502	5779	4014
EIF4G1	-2868	-940	4004	1882	-227
ETF1	-5256	-1911	4663	-25	4397
FAU	-7265	-3975	4740	233	1443
GSPT1	-2286	-956	-604	2009	-353
LDB1	-2901	-6560	2875	5453	5999
NCBP1	-2607	-1945	2448	8402	8509
NCBP2	-3917	-5147	2973	6756	7623
PABPC1	-3400	-5506	4238	5582	1293
PSMA1	-8359	-8604	5104	1855	4650
PSMA2	-7938	-2161	5110	1432	8018
PSMA3	-2004	-4530	4184	8188	7955
PSMA5	-3753	-5163	4135	7049	6792
PSMA6	-5756	-9052	230	3273	5895
PSMA7	-5963	-1772	3526	2927	3736
PSMB1	-2258	-1758	1218	4974	2620
PSMB10	-1663	-6710	-165	6829	6594
PSMB3	-3839	-6905	4780	5497	4412
PSMB5	-89	-6668	-1101	7598	7952
PSMB6	-6634	-5888	2326	6558	5006
PSMB7	-5105	-6476	-481	6667	7933
PSMB8	-7792	-3686	5160	756	1587
PSMB9	-8032	-7032	4898	3199	1447
PSMC1	89	-6196	611	7227	6270
PSMC3	-4234	-5168	-1757	3247	5525
PSMC4	-5962	-6708	1563	2130	2138
PSMC5	-7766	-7267	5418	2470	428
PSMC6	-7087	-7964	4301	5996	2878
PSMD1	-1790	-8089	458	4661	6182
PSMD11	-1272	-2207	4285	6544	4390
PSMD12	-2535	-3717	20	7015	7973
PSMD13	-8546	-5774	4927	2662	-882
PSMD14	-2548	-5579	3518	3709	4574
PSMD2	-7305	-6402	3485	3621	4835
PSMD3	-6151	-6416	5506	2545	2496
PSMD4	-7964	-5567	754	5325	7149
PSMD6	-4518	-717	1908	2403	114
PSMD7	-3120	-8646	2963	5075	5520
PSMD8	-4369	-5263	1397	3011	5309
PSMD9	-1075	-5374	3215	4605	1840
PSME1	-4828	-2498	2379	209	820
PSME2	-3988	-5227	2344	6844	5159
PSME3	-502	-1677	210	3994	6092
PSME4	-4990	-8991	5997	207	-839
PSMF1	-490	-5529	-2618	4670	8624
RBX1	-8553	-7492	5617	651	240
RNPS1	-5625	-5883	3685	2173	1138
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
SLIT1	644	-9593	-2979	-672	8416
UBA52	-513	-1242	1530	5448	5828
UBB	-6553	-5964	-13	7418	8036
UBC	-8288	-7011	-1067	5810	7639
UPF2	-4419	-6130	3206	2503	1382
UPF3A	-4731	-2250	5839	2172	4276
USP33	-3204	-3393	4583	6511	4700

---

---

rRNA processing

rRNA processing

metric	value
setSize	149
pMANOVA	5.26e-06
p.adjustMANOVA	0.00112
s.dist	0.293
s.psf	0.0112
s.psb	-0.127
s.hcy	0.0637
s.folate	0.16
s.vitb12	0.2
p.psf	0.814
p.psb	0.00773
p.hcy	0.181
p.folate	0.000796
p.vitb12	2.78e-05

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	vitb12	folate
CSNK1E	8577	7983
RPS27A	8264	8228
RPS24	8504	7985
PES1	8026	8341
RPSA	8168	8071
RPL15	8423	7772
RPL34	8213	7954
UTP20	8426	7701
RIOK2	8233	7755
RPS25	7689	8288
RPL28	8337	7634
RPL9	8503	7462
RPS28	7739	8167
C1D	8248	7585
BYSL	8099	7563
DDX52	8105	7367
UTP6	8055	7403
DDX47	6894	8287
RPL41	7829	7287
RPS6	6880	8168

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
BMS1	-2776	-2778	-2326	3878	2450
BYSL	-4178	-9536	6111	7563	8099
C1D	-3010	-6362	1064	7585	8248
CSNK1D	-973	-7670	2239	1107	4901
CSNK1E	614	-3165	-729	7983	8577
DCAF13	-5830	-1699	3821	6595	7638
DDX21	-5888	-3897	3188	3469	6682
DDX47	334	-4037	-1806	8287	6894
DDX49	-4822	-5792	5371	-412	788
DDX52	-4300	-7923	2602	7367	8105
DHX37	-7569	-4973	5147	689	58
DIS3	-8552	-9237	3964	2928	1121
EBNA1BP2	-8700	-8946	1196	3873	5515
ELAC2	-1211	-5657	-1752	7506	7313
ERI1	-6742	-8109	4581	-851	-677
EXOSC10	-1296	-2277	1561	7129	5838
EXOSC2	-8729	-9244	2530	3525	4504
EXOSC3	-1149	-6526	748	501	4842
EXOSC4	-5949	-971	3231	1277	-86
EXOSC5	-6533	-4703	1943	-485	-100
EXOSC6	-1630	-2864	1276	6042	4034
EXOSC7	-8091	-8183	3484	4662	6982
EXOSC8	-8053	-4017	6064	3443	6272
FAU	-7265	-3975	4740	233	1443
FBL	-1016	-3458	-2129	7793	7043
FCF1	-388	-3791	-123	6479	8244
FTSJ3	-6448	-1225	-1655	4146	6605
GAR1	-3275	-7493	2470	7687	6649
GNL3	-2576	-2510	3435	216	3410
HEATR1	-4869	-3287	2084	3939	6174
IMP3	-6465	-6229	388	4395	4138
IMP4	-1644	-5137	-220	5827	4713
ISG20L2	-7334	-1485	5735	997	-952
LTV1	-4883	-1561	662	6380	6318
MPHOSPH10	-8327	-4667	4534	1092	-150
MPHOSPH6	-4444	-3883	2630	6246	6385
MRM1	-7788	-3515	2510	3590	5871
NCL	-5736	-2460	2823	872	2137
NHP2	-6903	-5797	4423	301	373
NIP7	-8733	-7995	4984	820	-21
NOB1	-1208	-2611	-131	4405	4604
NOC4L	-6156	-4743	-1501	665	502
NOL11	-4583	-2640	2367	3213	3045
NOL12	-8329	-7236	2920	4088	7991
NOL6	-7508	-8624	-40	4802	4970
NOP10	-1349	-8584	5068	5553	7616
NOP14	649	185	3743	2648	-494
NOP2	-5068	-5446	-489	904	6520
NOP56	-5280	-7733	2511	1724	4467
NOP58	-8048	-1193	4754	1322	6909
NSUN4	-6033	-4663	-748	3736	5054
PDCD11	-2614	-3039	1969	4218	1847
PELP1	-4092	-3704	3720	4290	5506
PES1	-2938	-8904	-2265	8341	8026
PNO1	-3481	-5763	266	5053	4129
PWP2	-7581	-2679	4980	608	-496
RBM28	-492	-4862	-522	3026	7719
RCL1	-4719	-6386	-1205	8222	2198
RIOK1	-869	-7955	-497	2384	8560
RIOK2	-4653	-8102	2370	7755	8233
RIOK3	-6720	-3909	348	1192	5569
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPP14	-6182	-3689	2495	7012	4934
RPP21	-4699	-6536	906	1823	4298
RPP25	-4651	-7431	-2548	991	3559
RPP30	-4130	-8638	3731	7603	7125
RPP38	-6757	-3693	5497	823	-465
RPP40	-7953	-7432	5100	-457	-660
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
RRP1	-4052	-2434	-355	1248	3362
RRP7A	-434	-3767	-483	5962	7569
RRP9	-6069	-5735	5668	1022	3846
SENP3	517	-4315	-2379	4693	3631
TBL3	-6351	-4910	3907	5814	1166
TEX10	-3423	-3222	3700	1160	6096
TFB1M	-8224	-5530	3453	2841	5213
THUMPD1	-1299	-7743	-2354	7215	7293
TSR1	-401	-7858	-615	1421	8087
UBA52	-513	-1242	1530	5448	5828
UTP15	-4172	-8340	2250	4993	5787
UTP20	-4309	-9369	1726	7701	8426
UTP3	-7407	-6686	4792	4201	2357
UTP6	-1554	-7039	-1982	7403	8055
WBSCR22	-804	-282	-787	7872	6653
WDR12	-2331	-8402	-1014	5442	8152
WDR18	-4202	-6937	-1636	7463	5776
WDR3	-3894	-2871	5316	1443	5073
WDR36	-4315	-1996	3648	2073	4211
WDR43	-7910	-5699	6105	5052	858
WDR75	-4477	-8608	3688	7541	7194
XRN2	-1731	-7300	2453	2897	4923

---

---

rRNA processing in the nucleus and cytosol

rRNA processing in the nucleus and cytosol

metric	value
setSize	145
pMANOVA	6.68e-06
p.adjustMANOVA	0.00112
s.dist	0.291
s.psf	0.0207
s.psb	-0.129
s.hcy	0.0709
s.folate	0.159
s.vitb12	0.193
p.psf	0.668
p.psb	0.00734
p.hcy	0.142
p.folate	0.000999
p.vitb12	6.51e-05

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	vitb12	folate
CSNK1E	8577	7983
RPS27A	8264	8228
RPS24	8504	7985
PES1	8026	8341
RPSA	8168	8071
RPL15	8423	7772
RPL34	8213	7954
UTP20	8426	7701
RIOK2	8233	7755
RPS25	7689	8288
RPL28	8337	7634
RPL9	8503	7462
RPS28	7739	8167
C1D	8248	7585
BYSL	8099	7563
DDX52	8105	7367
UTP6	8055	7403
DDX47	6894	8287
RPL41	7829	7287
RPS6	6880	8168

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
BMS1	-2776	-2778	-2326	3878	2450
BYSL	-4178	-9536	6111	7563	8099
C1D	-3010	-6362	1064	7585	8248
CSNK1D	-973	-7670	2239	1107	4901
CSNK1E	614	-3165	-729	7983	8577
DCAF13	-5830	-1699	3821	6595	7638
DDX21	-5888	-3897	3188	3469	6682
DDX47	334	-4037	-1806	8287	6894
DDX49	-4822	-5792	5371	-412	788
DDX52	-4300	-7923	2602	7367	8105
DHX37	-7569	-4973	5147	689	58
DIS3	-8552	-9237	3964	2928	1121
EBNA1BP2	-8700	-8946	1196	3873	5515
ERI1	-6742	-8109	4581	-851	-677
EXOSC10	-1296	-2277	1561	7129	5838
EXOSC2	-8729	-9244	2530	3525	4504
EXOSC3	-1149	-6526	748	501	4842
EXOSC4	-5949	-971	3231	1277	-86
EXOSC5	-6533	-4703	1943	-485	-100
EXOSC6	-1630	-2864	1276	6042	4034
EXOSC7	-8091	-8183	3484	4662	6982
EXOSC8	-8053	-4017	6064	3443	6272
FAU	-7265	-3975	4740	233	1443
FBL	-1016	-3458	-2129	7793	7043
FCF1	-388	-3791	-123	6479	8244
FTSJ3	-6448	-1225	-1655	4146	6605
GAR1	-3275	-7493	2470	7687	6649
GNL3	-2576	-2510	3435	216	3410
HEATR1	-4869	-3287	2084	3939	6174
IMP3	-6465	-6229	388	4395	4138
IMP4	-1644	-5137	-220	5827	4713
ISG20L2	-7334	-1485	5735	997	-952
LTV1	-4883	-1561	662	6380	6318
MPHOSPH10	-8327	-4667	4534	1092	-150
MPHOSPH6	-4444	-3883	2630	6246	6385
NCL	-5736	-2460	2823	872	2137
NHP2	-6903	-5797	4423	301	373
NIP7	-8733	-7995	4984	820	-21
NOB1	-1208	-2611	-131	4405	4604
NOC4L	-6156	-4743	-1501	665	502
NOL11	-4583	-2640	2367	3213	3045
NOL12	-8329	-7236	2920	4088	7991
NOL6	-7508	-8624	-40	4802	4970
NOP10	-1349	-8584	5068	5553	7616
NOP14	649	185	3743	2648	-494
NOP2	-5068	-5446	-489	904	6520
NOP56	-5280	-7733	2511	1724	4467
NOP58	-8048	-1193	4754	1322	6909
PDCD11	-2614	-3039	1969	4218	1847
PELP1	-4092	-3704	3720	4290	5506
PES1	-2938	-8904	-2265	8341	8026
PNO1	-3481	-5763	266	5053	4129
PWP2	-7581	-2679	4980	608	-496
RBM28	-492	-4862	-522	3026	7719
RCL1	-4719	-6386	-1205	8222	2198
RIOK1	-869	-7955	-497	2384	8560
RIOK2	-4653	-8102	2370	7755	8233
RIOK3	-6720	-3909	348	1192	5569
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPP14	-6182	-3689	2495	7012	4934
RPP21	-4699	-6536	906	1823	4298
RPP25	-4651	-7431	-2548	991	3559
RPP30	-4130	-8638	3731	7603	7125
RPP38	-6757	-3693	5497	823	-465
RPP40	-7953	-7432	5100	-457	-660
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
RRP1	-4052	-2434	-355	1248	3362
RRP7A	-434	-3767	-483	5962	7569
RRP9	-6069	-5735	5668	1022	3846
SENP3	517	-4315	-2379	4693	3631
TBL3	-6351	-4910	3907	5814	1166
TEX10	-3423	-3222	3700	1160	6096
THUMPD1	-1299	-7743	-2354	7215	7293
TSR1	-401	-7858	-615	1421	8087
UBA52	-513	-1242	1530	5448	5828
UTP15	-4172	-8340	2250	4993	5787
UTP20	-4309	-9369	1726	7701	8426
UTP3	-7407	-6686	4792	4201	2357
UTP6	-1554	-7039	-1982	7403	8055
WBSCR22	-804	-282	-787	7872	6653
WDR12	-2331	-8402	-1014	5442	8152
WDR18	-4202	-6937	-1636	7463	5776
WDR3	-3894	-2871	5316	1443	5073
WDR36	-4315	-1996	3648	2073	4211
WDR43	-7910	-5699	6105	5052	858
WDR75	-4477	-8608	3688	7541	7194
XRN2	-1731	-7300	2453	2897	4923

---

---

M Phase

M Phase

metric	value
setSize	272
pMANOVA	7.16e-06
p.adjustMANOVA	0.00112
s.dist	0.194
s.psf	-0.0579
s.psb	-0.0868
s.hcy	0.115
s.folate	0.107
s.vitb12	0.0436
p.psf	0.103
p.psb	0.0145
p.hcy	0.00114
p.folate	0.00264
p.vitb12	0.22

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	hcy	folate
CENPJ	5613	6967
CCNB2	4682	7856
PSMA3	4184	8188
LEMD2	5022	6806
VRK1	4985	6441
RCC1	6472	4803
STAG1	5829	5087
PCM1	4253	6955
BLZF1	4015	7341
NUP205	4686	6267
PSMA5	4135	7049
AURKB	5907	4882
SMC3	4416	6498
NSL1	4556	6255
PPP2R1B	3568	7877
PSMD11	4285	6544
KIF2C	4652	5934
DCTN3	5566	4936
PSMB3	4780	5497
PSMC6	4301	5996

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
AAAS	-4813	-3658	2354	1828	2776
ACTR1A	-7409	-7285	6228	2166	2934
AHCTF1	-958	-5776	-1162	5566	2735
AKAP9	-879	-2573	3852	3811	6300
ALMS1	-1678	-5983	-1625	6835	3815
ANAPC1	-4888	-4370	4561	5142	1218
ANAPC10	-404	-8610	-361	6447	2473
ANAPC11	-1837	-244	601	4297	4855
ANAPC2	-5187	-4944	5252	-135	-940
ANAPC4	-1773	-8700	4698	4531	5293
ANAPC5	-2266	-8728	1095	6000	7040
ANAPC7	-3940	-8396	2305	7272	5608
ANKLE2	-2924	-731	-8	-905	1706
APITD1	-7436	-4833	3086	-1142	-173
ARPP19	-3005	-9058	650	3356	2754
AURKB	-5215	-5327	5907	4882	2882
B9D2	-6812	-1761	3803	2128	3929
BANF1	-4278	-7582	1929	7554	3391
BIRC5	-5343	-8595	2843	5224	6417
BLZF1	-8234	-6978	4015	7341	7608
BUB1	-5409	-7034	-1899	3149	4435
BUB1B	-7490	-8066	1793	6952	3147
BUB3	-1044	-2492	-425	6580	5165
CC2D1B	-2209	-5632	4256	2926	244
CCNB1	-8633	-4816	6272	-1067	-816
CCNB2	-6798	-5895	4682	7856	8479
CDC16	-1108	-909	-2388	2815	1317
CDC20	-212	-931	-491	6613	4602
CDC23	-1180	-4858	84	8244	8117
CDCA5	-1121	-417	3175	3307	5915
CDCA8	-4157	-4002	538	7190	8272
CDK1	-3517	-5019	2450	2546	7363
CDK5RAP2	28	-3076	-2525	8391	8566
CENPA	-5443	-3670	4463	-64	856
CENPE	-2106	-3196	899	5698	6188
CENPF	552	-58	5351	4636	6138
CENPH	-166	-3676	-1863	7000	5510
CENPJ	-6986	-7834	5613	6967	4084
CENPK	-7596	-7798	2332	7331	3303
CENPL	-5982	-8049	2744	3755	4081
CENPM	-3068	-1127	3488	4808	3710
CENPN	-7748	-8268	3464	2589	1857
CENPO	-4585	-5217	2243	6228	3869
CENPP	-8987	-5989	4188	-475	-375
CENPQ	-5168	-8986	788	4612	6598
CENPT	-2887	-4406	2029	313	2718
CEP135	-2407	-7278	2548	5696	6485
CEP152	-5236	-2244	1653	2324	1765
CEP164	-629	-2996	713	7069	7016
CEP192	-7456	-8329	2199	4990	2630
CEP250	-8527	-6903	4881	512	1570
CEP63	-6556	-7691	4259	2923	2119
CEP70	-8174	-6676	3663	2986	1045
CEP76	-8869	-6415	6523	-621	-937
CEP78	-4928	-7490	5013	2801	-327
CHMP2A	-4412	-5990	3751	6470	5425
CHMP2B	-1760	-5679	1172	4483	2940
CHMP4A	-8629	-6757	3557	2746	6097
CHMP4B	35	-2199	-830	6687	7422
CHMP6	-41	-3642	638	7662	6991
CHMP7	-5810	-147	4685	1840	4961
CKAP5	-4894	-8730	4720	1363	835
CLASP1	-5095	-5549	1549	5253	6532
CLASP2	-5060	-3223	-1727	6396	6132
CLIP1	-5995	-5664	2164	-399	4405
CSNK1D	-973	-7670	2239	1107	4901
CSNK1E	614	-3165	-729	7983	8577
CSNK2A2	-276	-6345	-188	5902	-421
CSNK2B	-8437	-8556	3108	982	975
DCTN2	-3373	-6548	-2552	7412	7292
DCTN3	-8835	-5606	5566	4936	7213
DSN1	-2102	-4234	3232	2568	3430
DYNC1H1	-4365	-3256	5029	425	786
DYNC1I2	-6567	-7070	2439	2184	2874
DYNC1LI1	-5010	-1342	2070	1660	915
DYNC1LI2	-3958	-1793	-456	881	-232
DYNLL1	-6435	-1692	4607	677	956
DYNLL2	-1210	-5926	4788	4965	6455
EML4	-3099	-4202	1602	4552	1606
ENSA	-8334	-6420	2792	6414	6693
ESPL1	-5611	-8871	2600	5459	8069
FBXO5	-3518	-5961	1996	6669	2722
GOLGA2	-1576	-9411	1523	8189	7664
GORASP2	-2555	-4804	-692	1133	3292
H2AFX	-2264	-828	-738	1976	3608
HAUS1	-8924	-8346	-139	-894	3039
HAUS2	-4906	-6282	1391	4934	5752
HAUS4	-2796	-8059	1165	7833	8154
HAUS5	-8	-7132	-1633	7311	8354
HAUS6	-1545	-9508	2952	8197	8029
HAUS8	-2937	180	4673	-1340	158
HSP90AA1	-1474	-2948	4393	938	5308
INCENP	-4410	-8460	5832	4041	3256
ITGB3BP	-1579	-8699	-2272	7906	4726
KIF18A	-8597	-7811	5152	1274	-189
KIF23	-1214	-4433	2145	3872	4719
KIF2A	-1404	-1285	1265	7884	1754
KIF2C	-5335	-4400	4652	5934	7164
KNTC1	-4087	-2381	-2217	7127	5117
KPNB1	-6642	-3659	4322	363	1576
LBR	-6739	-8663	5971	1829	5800
LEMD2	-7011	-9314	5022	6806	1314
LEMD3	-2955	-5799	2330	3740	7474
LMNA	514	-8510	-2632	4679	3620
LMNB1	-7257	-5018	3817	4000	853
LPIN1	-5260	-5676	4157	-99	695
LPIN2	-3614	-3699	4654	1027	-843
MAD1L1	-2169	-893	4397	1233	2279
MAD2L1	-693	-4252	1421	6862	6842
MAPK1	-2717	-2873	-1146	3217	-292
MAPK3	-6889	-9407	-1492	8081	6172
MAPRE1	-6287	-7647	-1239	6750	6392
MCPH1	-7453	-3876	2053	3416	6331
MIS12	-5040	-5098	3865	137	2565
NCAPD2	-5731	-3819	5235	3412	6939
NCAPD3	-7289	-8818	5898	26	1663
NCAPG	-8251	-3881	2538	-1161	485
NCAPG2	-5001	-6097	5943	628	600
NCAPH	-8054	-3153	3362	5021	2924
NCAPH2	-3174	-5947	2787	1293	-969
NDC80	-7727	-3732	4054	3903	88
NDE1	-7104	-8550	191	5467	7621
NDEL1	-3675	-1775	5672	-63	2872
NEDD1	-3862	-288	6562	-1432	-923
NEK2	-5853	-6431	2954	4274	552
NEK6	-781	-879	-68	5548	-532
NEK7	-8404	-8016	4859	4892	5614
NEK9	-3776	-2283	4727	2679	471
NIPBL	-5701	-8674	4140	2415	-14
NME7	-5566	-6971	2648	6559	7203
NSL1	-7171	-7994	4556	6255	5553
NUDC	-5765	-4788	5046	1526	3072
NUF2	-4503	-7059	-2397	6976	4190
NUMA1	-687	-3103	-2615	-524	5695
NUP107	-2367	-5920	902	8020	7981
NUP133	-2192	-6208	-1034	6710	4350
NUP153	-4611	-8419	2123	1709	5952
NUP155	-938	-2261	778	3101	6606
NUP160	-4062	-2126	-1133	5658	7516
NUP188	-4111	-2994	3510	3714	3909
NUP205	-8245	-8394	4686	6267	6798
NUP210	-8192	-8465	2605	2001	-159
NUP214	-3272	-1704	2474	2228	1116
NUP35	-1551	-7219	-1373	8140	8243
NUP37	-7550	-421	4573	1438	1480
NUP43	-5408	-4131	4558	2582	2522
NUP50	-4714	-688	2999	1921	1935
NUP54	-1931	-4958	3515	3754	3208
NUP62	-1453	-8038	1978	7023	5407
NUP85	-7303	-8224	5526	3668	1520
NUP93	-3267	-3790	-2168	3175	6994
NUP98	-8199	-889	2149	7764	7066
ODF2	-7755	-1603	5376	-1003	-707
PAFAH1B1	-5211	-2836	5904	687	-129
PCM1	-1756	-7343	4253	6955	7282
PCNT	-1548	-9147	-1852	7093	4977
PDS5A	-8750	-3459	6341	166	2013
PDS5B	-8826	-3671	4713	-583	3187
PLK1	-4551	-1935	-118	2868	3399
PLK4	-1681	-3910	1944	5138	4393
PMF1	-8472	-8813	4661	3508	5960
POM121	-6127	-7922	5593	4069	6325
POM121C	-3786	-5219	3938	5072	3069
PPP1CC	383	-760	-109	3143	1760
PPP2CA	-4081	-3471	4425	2847	2701
PPP2CB	-1353	77	5390	-624	-872
PPP2R1B	-1840	-3560	3568	7877	5301
PPP2R2A	-144	-5849	1125	5472	6709
PPP2R5A	-7527	-7188	1532	3085	360
PPP2R5B	-4467	-4603	1078	4371	2363
PPP2R5C	-3793	-9136	3153	2104	6783
PPP2R5D	-2176	-6920	-2111	6390	7682
PPP2R5E	-551	-1739	863	6882	7627
PRKACA	-4718	-4025	-1287	480	3795
PRKCA	-5820	-4955	3971	3486	5016
PRKCB	-8182	-7652	5627	-1153	-988
PSMA1	-8359	-8604	5104	1855	4650
PSMA2	-7938	-2161	5110	1432	8018
PSMA3	-2004	-4530	4184	8188	7955
PSMA5	-3753	-5163	4135	7049	6792
PSMA6	-5756	-9052	230	3273	5895
PSMA7	-5963	-1772	3526	2927	3736
PSMB1	-2258	-1758	1218	4974	2620
PSMB10	-1663	-6710	-165	6829	6594
PSMB3	-3839	-6905	4780	5497	4412
PSMB5	-89	-6668	-1101	7598	7952
PSMB6	-6634	-5888	2326	6558	5006
PSMB7	-5105	-6476	-481	6667	7933
PSMB8	-7792	-3686	5160	756	1587
PSMB9	-8032	-7032	4898	3199	1447
PSMC1	89	-6196	611	7227	6270
PSMC3	-4234	-5168	-1757	3247	5525
PSMC4	-5962	-6708	1563	2130	2138
PSMC5	-7766	-7267	5418	2470	428
PSMC6	-7087	-7964	4301	5996	2878
PSMD1	-1790	-8089	458	4661	6182
PSMD11	-1272	-2207	4285	6544	4390
PSMD12	-2535	-3717	20	7015	7973
PSMD13	-8546	-5774	4927	2662	-882
PSMD14	-2548	-5579	3518	3709	4574
PSMD2	-7305	-6402	3485	3621	4835
PSMD3	-6151	-6416	5506	2545	2496
PSMD4	-7964	-5567	754	5325	7149
PSMD6	-4518	-717	1908	2403	114
PSMD7	-3120	-8646	2963	5075	5520
PSMD8	-4369	-5263	1397	3011	5309
PSMD9	-1075	-5374	3215	4605	1840
PSME1	-4828	-2498	2379	209	820
PSME2	-3988	-5227	2344	6844	5159
PSME3	-502	-1677	210	3994	6092
PSME4	-4990	-8991	5997	207	-839
PSMF1	-490	-5529	-2618	4670	8624
PTTG1	-6300	-7345	144	7353	5706
RAB1A	-6184	-6579	5660	3203	2130
RAB1B	-2863	-5525	2090	5130	4433
RAB2A	-7010	-5090	4608	961	2595
RAD21	-6823	-6698	-54	7352	7315
RAE1	-8303	-1469	2950	2287	4628
RAN	215	-1000	-1174	7323	7330
RANBP2	-3530	-4429	-1283	4903	6045
RANGAP1	-1482	-1294	-174	7332	7247
RB1	-3440	-7436	2475	4145	2659
RCC1	-8899	-1220	6472	4803	-1137
RCC2	-4789	-1909	3142	1194	346
RPS27A	-6317	-9335	373	8228	8264
SDCCAG8	-4645	-2484	4907	4864	2284
SEC13	-8747	-6731	4873	-516	1432
SEH1L	-7723	-5493	4691	844	4470
SET	-7638	-9528	-2876	7004	5720
SIRT2	-3680	-1049	5840	3829	3363
SKA2	-9013	-5218	2224	8095	7700
SMC2	-9011	-8483	1629	6410	2042
SMC3	-5441	-8998	4416	6498	3310
SMC4	-8756	-6272	4224	-1396	-1099
SPAST	-7900	-8245	4541	1651	2766
SPC24	-4560	-3857	1317	4230	1955
SPC25	-2804	-6663	-1447	8021	7791
STAG1	-6618	-7770	5829	5087	5078
SUMO1	-1344	-2879	-2075	6159	7290
TAOK1	-5074	-852	6421	1847	383
TMPO	-1	-178	629	4115	1507
TNPO1	-3433	-5362	5407	2469	4010
TPR	-1912	-1701	2275	6893	903
TUBA1A	-3868	-6814	281	7982	5851
TUBA1B	-2586	-3957	1859	3184	4585
TUBA1C	-3611	-1926	3980	5273	1821
TUBA4A	-2725	-3627	757	7569	1248
TUBA4B	-8730	-3132	6556	-578	-182
TUBB	-6989	-2735	6157	-695	73
TUBB2A	-1141	-1970	-2479	3793	3564
TUBG2	-6985	-7753	1108	3397	4830
TUBGCP2	-8572	-9202	3059	-1079	125
TUBGCP3	-8505	-6714	6638	-52	4915
TUBGCP5	399	79	-2707	8176	1722
TUBGCP6	-8332	-6185	6580	-1186	-842
UBA52	-513	-1242	1530	5448	5828
UBB	-6553	-5964	-13	7418	8036
UBC	-8288	-7011	-1067	5810	7639
UBE2C	-759	-2829	-1688	6275	6660
UBE2D1	-2809	-3007	-157	1866	1336
UBE2E1	-4493	-4384	-1323	3040	2903
UBE2I	-3937	-1487	5265	-28	148
USO1	-8493	-8242	6098	1982	4249
VPS4A	-3975	-2950	2335	4622	5426
VRK1	-4206	-3102	4985	6441	4404
VRK2	-2498	-7336	-1683	8002	7219
XPO1	-6677	-4338	4933	4303	2828
YWHAE	138	-1017	-2211	1240	4019
YWHAG	-2464	-4668	3556	3296	1364
ZW10	-3358	-4465	-133	4675	7777
ZWILCH	-1670	-8800	-1593	8324	8308
ZWINT	-4132	-4213	2506	5868	2166

---

---

Translation

Translation

metric	value
setSize	225
pMANOVA	8.53e-06
p.adjustMANOVA	0.00112
s.dist	0.222
s.psf	-0.0157
s.psb	-0.0612
s.hcy	0.0863
s.folate	0.149
s.vitb12	0.125
p.psf	0.687
p.psb	0.116
p.hcy	0.0267
p.folate	0.000133
p.vitb12	0.00134

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
EIF4H	8386	8557
TARS2	8362	8483
MRPL47	8226	8513
MRPS21	8122	8510
MRPL30	8047	8478
RPS27A	8228	8264
RPS24	7985	8504
SSR2	8207	8103
EIF3K	7962	8324
RPSA	8071	8168
RPL15	7772	8423
RPL34	7954	8213
MRPS33	7992	8164
PTCD3	8109	8022
MRPS10	7836	8245
MRPS31	7966	8023
RPS25	8288	7689
RPL28	7634	8337
RPL9	7462	8503
RPS28	8167	7739

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
AARS2	-6296	-3899	43	1413	902
AIMP2	-8360	-2771	6569	-1212	-1217
APEH	-3371	-986	1926	6876	3482
AURKAIP1	-1094	-7949	-826	8219	3144
CARS2	-8046	-6326	5227	782	83
CHCHD1	-6970	-8890	2528	7269	942
DAP3	-6007	-8770	4420	7632	3089
EARS2	-4137	-6866	4064	7289	5765
EEF1A1	-3918	-942	2202	3605	6293
EEF1B2	-4047	-3617	1755	6724	7419
EEF1D	-190	-2379	3533	959	1093
EEF1E1	-5428	-6321	-1312	4897	6951
EEF1G	-5422	-4594	3051	186	2016
EEF2	-875	-295	765	5988	6454
EIF2B1	-5980	-1983	6306	353	-282
EIF2B2	-7978	-5656	5499	753	1735
EIF2B3	-2568	-538	-2206	1983	1527
EIF2B4	-7743	-3682	5026	180	663
EIF2B5	-7103	-6653	5033	770	3160
EIF2S1	-2735	-7410	-1488	6910	7442
EIF2S2	-8040	-2246	4352	4264	1966
EIF3A	-5961	-4394	2363	6467	6750
EIF3B	-7286	-5509	2356	6240	3808
EIF3E	-3852	-2014	1456	6310	8402
EIF3F	-8363	-6470	1695	4913	-256
EIF3G	-1270	-2190	3770	-171	649
EIF3H	-6307	-8861	5530	5136	7922
EIF3I	-1089	-1018	1281	-201	4343
EIF3J	-7128	-8079	1970	1279	1543
EIF3K	-2128	-8866	1472	7962	8324
EIF3L	-5319	-3996	-475	880	7020
EIF3M	-1877	-438	965	-129	2575
EIF4A1	-1333	-1250	3847	5915	4073
EIF4A2	-2633	-5470	2412	8016	6992
EIF4B	-7712	-3860	3758	2671	3062
EIF4E	-2494	-478	798	-590	2108
EIF4EBP1	-1302	-577	4751	5966	4456
EIF4G1	-2868	-940	4004	1882	-227
EIF4H	418	-9576	-3055	8386	8557
EIF5	-1766	-4636	1739	2798	3414
EIF5B	-5056	-8930	2159	5991	7633
ERAL1	-158	-1271	1794	7911	6412
ETF1	-5256	-1911	4663	-25	4397
FARSA	-3291	-5517	-757	3204	958
FARSB	-7498	-6638	275	5363	5685
FAU	-7265	-3975	4740	233	1443
GADD45GIP1	199	-2800	-818	7827	6760
GFM1	-5651	-8179	5195	1669	-448
GFM2	-8191	-3352	2245	3148	673
GSPT1	-2286	-956	-604	2009	-353
HARS2	-8017	-5862	-266	3147	6498
IARS2	-8319	-7864	-562	-241	2294
LARS2	-2934	-6114	1031	1908	6908
MARS2	-7312	-4538	3873	4188	4087
MRPL1	-6746	-1787	4570	7006	6815
MRPL10	-786	-1007	-761	7697	7848
MRPL11	-4880	-5875	3265	147	4182
MRPL12	-1309	-4997	466	5591	6287
MRPL13	-8735	-8223	5810	7092	8224
MRPL14	-667	-1051	-1838	990	-365
MRPL15	-6415	-1389	2980	2411	519
MRPL16	-5061	-8449	-9	-1346	4
MRPL18	-4852	-5844	4786	2600	5318
MRPL19	-37	-2804	-1571	8025	6914
MRPL2	-2035	-1712	5589	6617	7012
MRPL20	-5258	-279	6475	6209	8374
MRPL21	-5905	-7227	5658	-102	82
MRPL22	-5660	-3584	2829	5218	6730
MRPL23	-4356	-332	1211	1446	8300
MRPL24	-6024	-9230	544	5181	7055
MRPL27	-9122	-3983	-2894	7736	5669
MRPL30	-381	-5023	-740	8047	8478
MRPL32	-6875	-6791	5231	4062	897
MRPL33	-5607	-1372	2688	2630	2837
MRPL34	-4430	-3074	3070	3831	204
MRPL35	-7932	-5420	5628	6889	6736
MRPL36	-6712	-3186	4805	-314	6421
MRPL37	515	-8615	-2025	7358	7851
MRPL38	-5298	-5169	4038	-142	2528
MRPL39	-6150	-7950	4675	7494	4407
MRPL4	-3486	-1691	1073	787	4050
MRPL41	-5024	-259	6710	-27	-1111
MRPL42	-650	-2487	-2221	7815	7845
MRPL43	-7340	-9357	6513	-1040	-378
MRPL44	-5863	-4431	2097	4705	6664
MRPL45	710	113	1302	4727	-801
MRPL46	-7835	-8797	805	6439	7263
MRPL47	-1975	-9059	-2399	8226	8513
MRPL48	-237	-6807	2520	5073	3773
MRPL49	-2765	-5731	2364	4037	1481
MRPL50	-9045	-5855	6409	-611	1858
MRPL51	-5932	-5584	-1595	1507	1375
MRPL52	-8042	-7924	1496	5168	4640
MRPL53	-7601	-6156	6462	726	501
MRPL54	-3548	-3233	1499	6395	6013
MRPL55	-178	-5597	-1737	7303	6025
MRPS10	-1327	-8848	-1956	7836	8245
MRPS11	-6223	-7195	-1268	7667	6295
MRPS12	-1412	-5515	4695	5286	5884
MRPS14	-8654	-4048	6551	1431	126
MRPS15	-7406	-3985	2923	2580	-688
MRPS16	-2402	-7485	3746	7028	5072
MRPS17	-208	-747	-2139	5154	5012
MRPS18A	-301	-2716	-1132	3867	7520
MRPS18B	-6513	-464	-2977	4629	4528
MRPS18C	-3578	-7636	5532	3802	-566
MRPS2	-5575	-6964	-195	2764	8381
MRPS21	-6094	-6447	1047	8122	8510
MRPS22	-1363	-2551	5237	2055	5524
MRPS23	-644	-3801	-888	5857	2823
MRPS24	-7840	-8490	6051	-87	1621
MRPS25	-5834	-4571	3358	1033	6685
MRPS26	-3077	-3406	-115	6194	6018
MRPS27	-4557	-6422	-1266	7438	6001
MRPS28	-8155	-8992	-582	4382	5471
MRPS30	-5315	-8450	715	6402	8170
MRPS31	-956	-7595	-931	7966	8023
MRPS33	-2679	-4289	1141	7992	8164
MRPS34	-4617	-2122	705	1675	2244
MRPS35	-5432	-8124	3409	902	2267
MRPS36	-522	-4459	-1285	6353	2121
MRPS5	-3504	-3293	2558	2651	1888
MRPS6	-542	-1071	-1900	774	-219
MRPS7	-6821	-5037	5357	442	-441
MRPS9	-7831	-9081	5813	3510	5237
MTFMT	-5091	-2495	200	729	3352
MTIF2	-3294	-3135	3229	6816	7375
MTIF3	-7133	-5631	5696	1863	2658
MTRF1L	-7574	-3870	3048	4244	6509
N6AMT1	-6457	-1073	1655	3174	6658
NARS2	-5966	-7828	4574	4161	7611
OXA1L	377	-6751	1349	8131	6365
PABPC1	-3400	-5506	4238	5582	1293
PARS2	-5615	-572	2564	3144	5711
PPA1	-3321	-1940	4533	745	5386
PPA2	-2118	-7464	4071	4858	4372
PTCD3	-1408	-7358	-670	8109	8022
RARS2	-7264	-3466	4709	1340	5450
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPN1	-5829	-6529	4758	2203	1809
RPN2	-7930	-2850	-773	5499	3675
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
SARS2	-8811	-2530	6154	-606	-572
SEC11A	-5755	-7162	2830	5992	4108
SEC11C	-3733	-8634	5529	2181	-737
SEC61A1	-7089	-490	3623	663	-772
SEC61A2	-738	-3246	-2097	5197	4400
SEC61G	-6334	-3621	1774	4736	5281
SPCS2	-5763	-3911	321	4754	4075
SPCS3	-7739	-7437	4489	5750	2469
SRP14	-1346	-3506	652	7728	7410
SRP19	-268	-7901	3247	5734	5955
SRP54	-7158	-6849	1166	5353	4587
SRP68	-7538	-5835	6216	1381	-242
SRP72	-4076	-8342	1611	5621	6027
SRPRB	-2995	-6434	2948	3037	5236
SSR1	-3286	-1615	1511	-313	4618
SSR2	-4122	-5033	-1575	8207	8103
SSR3	-8775	-4685	3472	2528	2715
TARS2	-1132	-7015	-15	8362	8483
TRAM1	-8485	-9025	3237	-687	-300
TSFM	-5316	-7071	2654	6415	6525
TUFM	-1864	-8200	1588	7516	470
UBA52	-513	-1242	1530	5448	5828
VARS2	-303	-5204	-1138	3461	2611
WARS2	-4166	-5009	1831	3396	4041
YARS2	-3470	-6904	3065	5089	6838

---

---

Processing of Capped Intron-Containing Pre-mRNA

Processing of Capped Intron-Containing Pre-mRNA

metric	value
setSize	175
pMANOVA	9.56e-06
p.adjustMANOVA	0.00112
s.dist	0.219
s.psf	-0.135
s.psb	-0.015
s.hcy	0.11
s.folate	0.124
s.vitb12	0.0467
p.psf	0.00214
p.psb	0.733
p.hcy	0.0128
p.folate	0.00492
p.vitb12	0.289

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	psf	folate
PPIL6	-9118	7640
NUP98	-8199	7764
DNAJC8	-7353	7931
U2AF1L4	-8452	6821
RNU12	-6802	8329
SNW1	-7556	7224
NUP205	-8245	6267
POLR2K	-6692	7535
HNRNPC	-6417	7786
PPIL3	-6835	6931
HNRNPK	-8708	5391
DDX42	-6054	7469
SYF2	-6245	6860
NXF1	-6326	6707
CRNKL1	-8653	4891
SNRNP27	-8613	4890
ISY1	-7742	5327
SYMPK	-8912	4534
SNRPG	-8824	4428
PRPF3	-4650	8106

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
AAAS	-4813	-3658	2354	1828	2776
AQR	-6333	-3041	3130	2428	213
BUD31	-5822	-1257	5663	1158	-128
CASC3	-5894	-3543	-120	2750	7789
CCAR1	-6114	-4153	4117	2954	1555
CD2BP2	-7752	-6379	-565	2299	225
CDC40	-5069	-5170	6113	7236	7911
CDC5L	-3718	-8684	2708	4035	466
CHERP	-1036	-1544	150	7588	7250
CLP1	-8309	-8541	3767	4503	5311
CPSF1	-7857	-2180	1761	-275	3766
CPSF2	-8923	-7853	5634	4004	1174
CPSF3	-9106	-320	3820	-995	-1008
CPSF4	-2416	-2946	3597	65	1707
CRNKL1	-8653	-1313	6082	4891	-53
CSTF1	-8368	-1269	6211	3962	-798
CTNNBL1	-260	-2124	-1675	5289	7206
CWC15	-5234	-9143	500	5096	5887
CWC22	-2356	-1364	-624	8283	8440
DDX23	-5303	-5813	1255	6302	2957
DDX42	-6054	-3242	-750	7469	7080
DDX46	-3736	-5546	1628	489	170
DDX5	-8798	-1962	5815	765	8110
DHX16	-6357	-5208	3655	2330	1654
DHX9	-2881	-5212	3182	2843	5648
DNAJC8	-7353	-9020	341	7931	8344
EFTUD2	-6446	-4389	556	371	6704
EIF4A3	-1889	-241	4502	5779	4014
EIF4E	-2494	-478	798	-590	2108
FIP1L1	-3659	-5017	3181	598	4518
FUS	-8674	-8601	5569	646	297
FYTTD1	-7249	-4238	5845	314	-862
GLE1	666	-7622	-1801	8318	8571
GTF2F1	-6478	-3375	-601	1836	7032
GTF2F2	-4911	-5801	2754	5927	6569
HNRNPA0	-3798	-5600	3243	1046	969
HNRNPA2B1	-5709	-2656	1320	2348	6171
HNRNPC	-6417	-4531	-444	7786	5488
HNRNPD	-4568	-1459	4662	3947	2001
HNRNPF	-4034	-5253	2984	1175	1921
HNRNPH1	-5132	-5113	6459	7063	112
HNRNPK	-8708	-3748	2280	5391	2404
HNRNPL	-2126	-3202	1676	2831	630
HNRNPM	-2262	-6986	-2261	3606	6840
HNRNPR	-8622	-2736	6282	-218	176
HNRNPU	-3813	-1254	860	5008	5617
HNRNPUL1	-3147	-3194	4088	5579	5341
ISY1	-7742	-8825	5271	5327	3431
LSM2	-2021	-1145	-593	6198	4951
LSM3	-2989	-3969	-1227	4544	7387
LSM4	-8436	-1999	5635	3901	3659
LSM5	-6751	-6566	2041	3840	3828
LSM6	-5542	-4880	3191	6797	2059
LSM7	-4523	-8629	-859	6494	-776
METTL14	-8615	-8682	1352	62	5452
NCBP1	-2607	-1945	2448	8402	8509
NCBP2	-3917	-5147	2973	6756	7623
NUDT21	-8225	-7782	5559	3640	1124
NUP107	-2367	-5920	902	8020	7981
NUP133	-2192	-6208	-1034	6710	4350
NUP153	-4611	-8419	2123	1709	5952
NUP155	-938	-2261	778	3101	6606
NUP160	-4062	-2126	-1133	5658	7516
NUP188	-4111	-2994	3510	3714	3909
NUP205	-8245	-8394	4686	6267	6798
NUP210	-8192	-8465	2605	2001	-159
NUP214	-3272	-1704	2474	2228	1116
NUP35	-1551	-7219	-1373	8140	8243
NUP37	-7550	-421	4573	1438	1480
NUP43	-5408	-4131	4558	2582	2522
NUP50	-4714	-688	2999	1921	1935
NUP54	-1931	-4958	3515	3754	3208
NUP62	-1453	-8038	1978	7023	5407
NUP85	-7303	-8224	5526	3668	1520
NUP93	-3267	-3790	-2168	3175	6994
NUP98	-8199	-889	2149	7764	7066
NXF1	-6326	-5554	4304	6707	3030
NXT1	-6627	-8867	1191	2961	710
PABPN1	-5567	-8318	2534	6672	2442
PAPOLA	-8227	-6469	2436	1653	2471
PCBP1	-2567	-3030	182	6928	6076
PCBP2	-4517	-2508	4187	3727	1131
PDCD7	-4272	-3341	3565	6212	3034
PLRG1	-6202	-6583	4035	1766	5014
POLDIP3	-3702	-6669	1702	7198	7721
POLR2A	-8657	-6301	3361	1117	-706
POLR2B	-2551	-7510	1297	5291	7059
POLR2C	-375	-2722	2661	3775	1272
POLR2D	-4623	-6633	1251	-240	862
POLR2E	-7280	-5905	1641	2768	1465
POLR2F	-2647	22	2490	337	2732
POLR2G	-3892	-6713	3633	6708	4000
POLR2H	-3216	-2022	5045	1005	994
POLR2I	-6360	-3343	1067	691	4207
POLR2K	-6692	-9353	-599	7535	6282
POM121	-6127	-7922	5593	4069	6325
POM121C	-3786	-5219	3938	5072	3069
PPIE	-3912	-9284	-319	4108	2543
PPIH	-7408	-5442	4546	4252	3083
PPIL1	-4920	-7462	3201	5396	1591
PPIL3	-6835	-2869	3210	6931	7856
PPIL4	-2779	-5560	1024	2797	3962
PPIL6	-9118	-7739	6689	7640	2461
PPWD1	-5342	-492	37	143	2520
PRCC	-4588	-8058	417	7046	4634
PRPF19	-4491	-7879	1425	5393	5122
PRPF3	-4650	-4881	-1404	8106	7172
PRPF31	-2670	-8967	-2121	7586	8477
PRPF38A	-2486	-8964	-1546	2573	3523
PRPF6	-1239	-6227	4827	4948	8123
PRPF8	-7782	-8620	4488	1852	1835
PTBP1	-813	-1190	921	4122	2968
PUF60	-1473	-835	2132	-56	3923
RAE1	-8303	-1469	2950	2287	4628
RANBP2	-3530	-4429	-1283	4903	6045
RBM17	-6730	-4323	5818	-372	2782
RNPC3	-5347	-4075	893	2772	7405
RNPS1	-5625	-5883	3685	2173	1138
RNU11	-4042	-8053	1371	8142	8094
RNU12	-6802	-790	-300	8329	8148
SART1	-2739	-4566	-653	6130	5049
SEC13	-8747	-6731	4873	-516	1432
SEH1L	-7723	-5493	4691	844	4470
SF1	-4832	-3244	1384	3310	4619
SF3A1	-6165	-5622	5669	-202	298
SF3A2	-159	-1064	5388	7866	8539
SF3A3	-3923	-5941	2407	2044	2601
SF3B2	-3556	-4464	3956	4587	3040
SF3B3	417	-9037	-2254	4250	5408
SF3B4	-1361	-7842	-2440	6419	7910
SF3B5	-3889	-860	5471	6211	5269
SLBP	-4277	-4143	4482	6615	1359
SLU7	-7719	-1038	4816	2793	7622
SMNDC1	-4988	-6052	2616	6156	5660
SNRNP200	-8215	-3814	6366	3481	731
SNRNP25	-6385	-7763	4650	2423	-671
SNRNP27	-8613	-4243	5262	4890	4486
SNRNP35	-7994	-7518	4093	-6	2731
SNRNP40	-791	-3141	694	7841	7635
SNRNP48	-7209	-227	225	3610	3769
SNRNP70	-7130	-7607	3062	5116	6103
SNRPA	-1672	-9302	3379	6333	864
SNRPA1	-2752	-2477	-1814	6325	7076
SNRPB	-6711	-3952	5645	4874	4918
SNRPB2	-1249	-6737	3845	3677	4178
SNRPC	-2341	-4312	-1742	8378	7966
SNRPD1	-341	-2294	5156	1350	2265
SNRPD2	-2587	-8080	5812	7972	203
SNRPD3	428	-1268	4403	8221	6276
SNRPE	-4552	-1609	2801	6300	602
SNRPG	-8824	-8240	2782	4428	6962
SNRPN	602	-4875	-871	8320	8000
SNW1	-7556	-9106	4302	7224	7892
SRRM1	-1123	-3198	143	7240	4545
SRRM2	407	-1575	5878	3259	1253
SRRT	-863	-3259	-122	-999	-607
SYF2	-6245	-7645	917	6860	6924
SYMPK	-8912	-7534	4027	4534	5149
TFIP11	-859	-2343	-1766	7655	5721
THOC1	-6047	-2930	2712	4926	482
THOC5	-4697	-6675	-1746	6249	7452
THOC7	-8896	-7895	3898	-1303	-195
TPR	-1912	-1701	2275	6893	903
TXNL4A	-2472	-359	3705	-98	-667
U2AF1	-6388	-3920	-1258	2776	2028
U2AF1L4	-8452	-3382	6502	6821	2490
U2AF2	-269	-3015	2075	2952	1484
USP39	-4669	-4333	-1921	4527	5860
WBP11	-3724	-8455	4297	6347	7147
WBP4	-7960	-8405	-1098	-845	-1183
WDR33	-4998	-3170	2377	1490	1142
WTAP	-6606	-2456	4617	3380	5010
XAB2	-8628	-6086	-396	4099	5265
YBX1	-5841	-1802	2033	2163	6021
ZMAT5	-1025	-629	-2802	-1367	-1219

---

---

Activation of NMDA receptors and postsynaptic events

Activation of NMDA receptors and postsynaptic events

metric	value
setSize	43
pMANOVA	9.8e-06
p.adjustMANOVA	0.00112
s.dist	0.494
s.psf	0.191
s.psb	0.228
s.hcy	-0.28
s.folate	-0.228
s.vitb12	-0.158
p.psf	0.03
p.psb	0.00966
p.hcy	0.00151
p.folate	0.0097
p.vitb12	0.073

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	hcy	psb
GRIN1	-2485	71

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
APBA1	-2203	-6452	-1859	4747	3277
ARHGEF7	-2889	-963	1038	6761	5725
CALM1	-1140	-3090	-703	2569	5919
CAMK1	622	-1001	-2658	4883	-605
CAMK2D	-7602	-2920	6135	-628	-174
CAMK2G	-250	-62	-829	6968	1605
CAMK4	-258	-3558	2726	1835	284
CAMKK1	-5757	-5738	4543	-336	2542
CAMKK2	-3279	-6235	-2051	293	4332
CREB1	-4159	-1226	472	-273	3361
DLG1	-385	-1091	2874	5485	1201
DLG4	-1757	-7935	-1172	5776	4723
GIT1	443	-5279	-3090	718	4910
GRIN1	244	71	-2485	1161	-555
GRIN2C	-810	-8353	-2408	-394	3376
GRIN2D	-1104	-8108	-2134	1042	7433
HRAS	348	-304	-2761	2241	5443
KIF17	-1489	-1198	2947	8037	8202
KPNA2	-7476	-5242	4362	3922	198
KRAS	-3001	-89	138	-784	-790
LIN7B	-4201	-998	-741	4	4069
LIN7C	-2622	-5235	606	1159	2749
MAPK1	-2717	-2873	-1146	3217	-292
MAPK3	-6889	-9407	-1492	8081	6172
MAPT	-2959	-1119	201	2894	5154
NBEA	601	-1104	-1866	1043	-263
NRGN	-6866	-2345	776	6581	2683
PDPK1	-6239	-376	3800	444	2190
PPM1F	-2561	-5038	-1585	302	4984
PRKAA1	-4171	-954	-1152	5406	5062
PRKAB1	-6437	-4951	5662	-167	1351
PRKAB2	-3725	-7118	1621	5427	2154
PRKACA	-4718	-4025	-1287	480	3795
PRKACB	-6646	-908	2348	1167	1023
PRKAG1	-6626	-8822	4778	-622	4636
PRKAG2	-4216	-7353	4444	8	3106
PRKAR1A	-7139	-2501	4900	-147	424
PRKAR1B	-265	-107	-3015	7076	7451
PRKAR2A	-825	-2422	-2557	771	3315
RAC1	-2096	-4182	1706	2583	1143
RPS6KA1	-5437	-3891	-2723	-627	1954
RPS6KA2	-5884	-402	3112	3010	3312
SRC	-5098	-8229	-427	-41	-814

---

---

Mitotic Metaphase and Anaphase

Mitotic Metaphase and Anaphase

metric	value
setSize	186
pMANOVA	2.4e-05
p.adjustMANOVA	0.00239
s.dist	0.227
s.psf	-0.026
s.psb	-0.0504
s.hcy	0.094
s.folate	0.168
s.vitb12	0.107
p.psf	0.543
p.psb	0.238
p.hcy	0.0279
p.folate	8.41e-05
p.vitb12	0.0127

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
ZWILCH	8324	8308
RPS27A	8228	8264
NUP35	8140	8243
CDC23	8244	8117
CCNB2	7856	8479
PSMA3	8188	7955
NUP107	8020	7981
SPC25	8021	7791
SKA2	8095	7700
PSMB5	7598	7952
UBB	7418	8036
CDCA8	7190	8272
VRK2	8002	7219
PSMD12	7015	7973
NUP98	7764	7066
RAD21	7352	7315
RAN	7323	7330
CHMP6	7662	6991
RANGAP1	7332	7247
PSMB7	6667	7933

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
AHCTF1	-958	-5776	-1162	5566	2735
ANAPC1	-4888	-4370	4561	5142	1218
ANAPC10	-404	-8610	-361	6447	2473
ANAPC11	-1837	-244	601	4297	4855
ANAPC2	-5187	-4944	5252	-135	-940
ANAPC4	-1773	-8700	4698	4531	5293
ANAPC5	-2266	-8728	1095	6000	7040
ANAPC7	-3940	-8396	2305	7272	5608
ANKLE2	-2924	-731	-8	-905	1706
APITD1	-7436	-4833	3086	-1142	-173
AURKB	-5215	-5327	5907	4882	2882
B9D2	-6812	-1761	3803	2128	3929
BANF1	-4278	-7582	1929	7554	3391
BIRC5	-5343	-8595	2843	5224	6417
BUB1	-5409	-7034	-1899	3149	4435
BUB1B	-7490	-8066	1793	6952	3147
BUB3	-1044	-2492	-425	6580	5165
CC2D1B	-2209	-5632	4256	2926	244
CCNB1	-8633	-4816	6272	-1067	-816
CCNB2	-6798	-5895	4682	7856	8479
CDC16	-1108	-909	-2388	2815	1317
CDC20	-212	-931	-491	6613	4602
CDC23	-1180	-4858	84	8244	8117
CDCA5	-1121	-417	3175	3307	5915
CDCA8	-4157	-4002	538	7190	8272
CDK1	-3517	-5019	2450	2546	7363
CENPA	-5443	-3670	4463	-64	856
CENPE	-2106	-3196	899	5698	6188
CENPF	552	-58	5351	4636	6138
CENPH	-166	-3676	-1863	7000	5510
CENPK	-7596	-7798	2332	7331	3303
CENPL	-5982	-8049	2744	3755	4081
CENPM	-3068	-1127	3488	4808	3710
CENPN	-7748	-8268	3464	2589	1857
CENPO	-4585	-5217	2243	6228	3869
CENPP	-8987	-5989	4188	-475	-375
CENPQ	-5168	-8986	788	4612	6598
CENPT	-2887	-4406	2029	313	2718
CHMP2A	-4412	-5990	3751	6470	5425
CHMP2B	-1760	-5679	1172	4483	2940
CHMP4A	-8629	-6757	3557	2746	6097
CHMP4B	35	-2199	-830	6687	7422
CHMP6	-41	-3642	638	7662	6991
CHMP7	-5810	-147	4685	1840	4961
CKAP5	-4894	-8730	4720	1363	835
CLASP1	-5095	-5549	1549	5253	6532
CLASP2	-5060	-3223	-1727	6396	6132
CLIP1	-5995	-5664	2164	-399	4405
DSN1	-2102	-4234	3232	2568	3430
DYNC1H1	-4365	-3256	5029	425	786
DYNC1I2	-6567	-7070	2439	2184	2874
DYNC1LI1	-5010	-1342	2070	1660	915
DYNC1LI2	-3958	-1793	-456	881	-232
DYNLL1	-6435	-1692	4607	677	956
DYNLL2	-1210	-5926	4788	4965	6455
ESPL1	-5611	-8871	2600	5459	8069
FBXO5	-3518	-5961	1996	6669	2722
INCENP	-4410	-8460	5832	4041	3256
ITGB3BP	-1579	-8699	-2272	7906	4726
KIF18A	-8597	-7811	5152	1274	-189
KIF2A	-1404	-1285	1265	7884	1754
KIF2C	-5335	-4400	4652	5934	7164
KNTC1	-4087	-2381	-2217	7127	5117
KPNB1	-6642	-3659	4322	363	1576
LBR	-6739	-8663	5971	1829	5800
LEMD2	-7011	-9314	5022	6806	1314
LEMD3	-2955	-5799	2330	3740	7474
LMNA	514	-8510	-2632	4679	3620
LMNB1	-7257	-5018	3817	4000	853
MAD1L1	-2169	-893	4397	1233	2279
MAD2L1	-693	-4252	1421	6862	6842
MAPRE1	-6287	-7647	-1239	6750	6392
MIS12	-5040	-5098	3865	137	2565
NDC80	-7727	-3732	4054	3903	88
NDE1	-7104	-8550	191	5467	7621
NDEL1	-3675	-1775	5672	-63	2872
NSL1	-7171	-7994	4556	6255	5553
NUDC	-5765	-4788	5046	1526	3072
NUF2	-4503	-7059	-2397	6976	4190
NUP107	-2367	-5920	902	8020	7981
NUP133	-2192	-6208	-1034	6710	4350
NUP155	-938	-2261	778	3101	6606
NUP160	-4062	-2126	-1133	5658	7516
NUP188	-4111	-2994	3510	3714	3909
NUP205	-8245	-8394	4686	6267	6798
NUP35	-1551	-7219	-1373	8140	8243
NUP37	-7550	-421	4573	1438	1480
NUP43	-5408	-4131	4558	2582	2522
NUP54	-1931	-4958	3515	3754	3208
NUP62	-1453	-8038	1978	7023	5407
NUP85	-7303	-8224	5526	3668	1520
NUP93	-3267	-3790	-2168	3175	6994
NUP98	-8199	-889	2149	7764	7066
PAFAH1B1	-5211	-2836	5904	687	-129
PDS5A	-8750	-3459	6341	166	2013
PDS5B	-8826	-3671	4713	-583	3187
PLK1	-4551	-1935	-118	2868	3399
PMF1	-8472	-8813	4661	3508	5960
POM121	-6127	-7922	5593	4069	6325
PPP1CC	383	-760	-109	3143	1760
PPP2CA	-4081	-3471	4425	2847	2701
PPP2CB	-1353	77	5390	-624	-872
PPP2R1B	-1840	-3560	3568	7877	5301
PPP2R2A	-144	-5849	1125	5472	6709
PPP2R5A	-7527	-7188	1532	3085	360
PPP2R5B	-4467	-4603	1078	4371	2363
PPP2R5C	-3793	-9136	3153	2104	6783
PPP2R5D	-2176	-6920	-2111	6390	7682
PPP2R5E	-551	-1739	863	6882	7627
PSMA1	-8359	-8604	5104	1855	4650
PSMA2	-7938	-2161	5110	1432	8018
PSMA3	-2004	-4530	4184	8188	7955
PSMA5	-3753	-5163	4135	7049	6792
PSMA6	-5756	-9052	230	3273	5895
PSMA7	-5963	-1772	3526	2927	3736
PSMB1	-2258	-1758	1218	4974	2620
PSMB10	-1663	-6710	-165	6829	6594
PSMB3	-3839	-6905	4780	5497	4412
PSMB5	-89	-6668	-1101	7598	7952
PSMB6	-6634	-5888	2326	6558	5006
PSMB7	-5105	-6476	-481	6667	7933
PSMB8	-7792	-3686	5160	756	1587
PSMB9	-8032	-7032	4898	3199	1447
PSMC1	89	-6196	611	7227	6270
PSMC3	-4234	-5168	-1757	3247	5525
PSMC4	-5962	-6708	1563	2130	2138
PSMC5	-7766	-7267	5418	2470	428
PSMC6	-7087	-7964	4301	5996	2878
PSMD1	-1790	-8089	458	4661	6182
PSMD11	-1272	-2207	4285	6544	4390
PSMD12	-2535	-3717	20	7015	7973
PSMD13	-8546	-5774	4927	2662	-882
PSMD14	-2548	-5579	3518	3709	4574
PSMD2	-7305	-6402	3485	3621	4835
PSMD3	-6151	-6416	5506	2545	2496
PSMD4	-7964	-5567	754	5325	7149
PSMD6	-4518	-717	1908	2403	114
PSMD7	-3120	-8646	2963	5075	5520
PSMD8	-4369	-5263	1397	3011	5309
PSMD9	-1075	-5374	3215	4605	1840
PSME1	-4828	-2498	2379	209	820
PSME2	-3988	-5227	2344	6844	5159
PSME3	-502	-1677	210	3994	6092
PSME4	-4990	-8991	5997	207	-839
PSMF1	-490	-5529	-2618	4670	8624
PTTG1	-6300	-7345	144	7353	5706
RAD21	-6823	-6698	-54	7352	7315
RAN	215	-1000	-1174	7323	7330
RANBP2	-3530	-4429	-1283	4903	6045
RANGAP1	-1482	-1294	-174	7332	7247
RCC1	-8899	-1220	6472	4803	-1137
RCC2	-4789	-1909	3142	1194	346
RPS27A	-6317	-9335	373	8228	8264
SEC13	-8747	-6731	4873	-516	1432
SEH1L	-7723	-5493	4691	844	4470
SIRT2	-3680	-1049	5840	3829	3363
SKA2	-9013	-5218	2224	8095	7700
SMC3	-5441	-8998	4416	6498	3310
SPAST	-7900	-8245	4541	1651	2766
SPC24	-4560	-3857	1317	4230	1955
SPC25	-2804	-6663	-1447	8021	7791
STAG1	-6618	-7770	5829	5087	5078
SUMO1	-1344	-2879	-2075	6159	7290
TAOK1	-5074	-852	6421	1847	383
TMPO	-1	-178	629	4115	1507
TNPO1	-3433	-5362	5407	2469	4010
TUBA1A	-3868	-6814	281	7982	5851
TUBA1B	-2586	-3957	1859	3184	4585
TUBA1C	-3611	-1926	3980	5273	1821
TUBA4A	-2725	-3627	757	7569	1248
TUBA4B	-8730	-3132	6556	-578	-182
TUBB2A	-1141	-1970	-2479	3793	3564
UBA52	-513	-1242	1530	5448	5828
UBB	-6553	-5964	-13	7418	8036
UBC	-8288	-7011	-1067	5810	7639
UBE2C	-759	-2829	-1688	6275	6660
UBE2D1	-2809	-3007	-157	1866	1336
UBE2E1	-4493	-4384	-1323	3040	2903
UBE2I	-3937	-1487	5265	-28	148
VPS4A	-3975	-2950	2335	4622	5426
VRK1	-4206	-3102	4985	6441	4404
VRK2	-2498	-7336	-1683	8002	7219
XPO1	-6677	-4338	4933	4303	2828
ZW10	-3358	-4465	-133	4675	7777
ZWILCH	-1670	-8800	-1593	8324	8308
ZWINT	-4132	-4213	2506	5868	2166

---

---

Neuronal System

Neuronal System

metric	value
setSize	127
pMANOVA	2.55e-05
p.adjustMANOVA	0.00239
s.dist	0.269
s.psf	0.0919
s.psb	0.103
s.hcy	-0.195
s.folate	-0.113
s.vitb12	-0.0499
p.psf	0.0747
p.psb	0.0461
p.hcy	0.000157
p.folate	0.0283
p.vitb12	0.333

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	hcy	folate
GNB1	-2592	-1002
ADCY7	-2990	-609
RPS6KA1	-2723	-627
PLCB3	-1041	-1010
GRIN2C	-2408	-394
PPFIA1	-600	-850
KCNQ4	-301	-1001
SRC	-427	-41

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
ABAT	-5243	-1324	-2789	1692	585
ADCY4	-4326	-2533	-1935	377	-183
ADCY7	-8384	-9239	-2990	-609	4432
ADCY9	-8670	-84	2546	2727	-326
ALDH5A1	-2246	-5305	297	2302	3311
AP2A1	-8799	-6898	4882	1998	207
AP2M1	-2247	-892	-611	4902	5257
AP2S1	-5172	-4343	-2469	8169	8393
APBA1	-2203	-6452	-1859	4747	3277
APBA2	192	-829	4493	7940	7491
APBA3	-8953	-233	6751	-221	-1204
ARHGEF7	-2889	-963	1038	6761	5725
ARL6IP5	-2946	-8504	-1851	7924	7238
CACNA2D2	-4793	-7194	3989	4081	5292
CALM1	-1140	-3090	-703	2569	5919
CAMK1	622	-1001	-2658	4883	-605
CAMK2D	-7602	-2920	6135	-628	-174
CAMK2G	-250	-62	-829	6968	1605
CAMK4	-258	-3558	2726	1835	284
CAMKK1	-5757	-5738	4543	-336	2542
CAMKK2	-3279	-6235	-2051	293	4332
CHRNA5	-6551	-6847	853	-985	304
CHRNB4	-999	-566	6666	-507	2037
CHRNE	390	-210	-2588	6007	6055
COMT	-7446	-9092	-1986	8218	7820
CREB1	-4159	-1226	472	-273	3361
DBNL	-1978	-5032	2529	890	1698
DLG1	-385	-1091	2874	5485	1201
DLG4	-1757	-7935	-1172	5776	4723
DLGAP1	-8623	-7594	5553	6609	2556
DLGAP3	-1377	-4378	-623	1289	1783
DLGAP4	-6760	-3763	-556	2258	4586
DNAJC5	-484	-54	-2896	3436	7899
EPB41	-3345	-4435	1247	383	1533
EPB41L5	-2600	-1914	-1671	105	183
FLOT1	-2107	-3156	-1915	3850	2390
FLOT2	-5640	-5730	1826	3698	1664
GABBR1	-539	-7192	-2447	2909	7972
GIT1	443	-5279	-3090	718	4910
GLS	-6017	-3405	-61	7562	3560
GLUL	-8463	-7643	-3101	8124	8084
GNAI2	-3270	-4506	1325	3664	3728
GNAI3	-4256	-6373	1076	7816	7566
GNAL	-5039	-3815	4412	4827	6369
GNB1	-7545	-2084	-2592	-1002	-473
GNB2	-6564	-4671	4217	2806	1836
GNB4	-5727	-7860	355	1400	5628
GNB5	-5029	-2955	2913	6045	4939
GNG12	-9078	-8896	6415	-1213	6604
GNG2	454	-690	4308	7887	6859
GNG4	682	214	2653	6944	7223
GNG5	-285	-98	3683	7410	108
GRIN1	244	71	-2485	1161	-555
GRIN2C	-810	-8353	-2408	-394	3376
GRIN2D	-1104	-8108	-2134	1042	7433
HCN3	-4855	-7105	1187	1923	2690
HOMER1	-2144	-7537	5039	-544	2926
HRAS	348	-304	-2761	2241	5443
IL1RAP	-4935	-3228	1938	1408	1360
KCNA3	-1607	-3896	6350	1761	871
KCNAB2	-4860	-3845	-2218	4242	5853
KCNC4	-8930	-9468	6599	1389	-1000
KCNG3	-176	-2351	586	7539	6619
KCNH2	-621	-2245	1548	-1054	7826
KCNH4	-349	-902	-2013	7496	6886
KCNJ11	-5201	-1949	-617	447	-785
KCNK6	-615	-375	-2361	741	5674
KCNMB4	-1120	-7169	-1481	6238	5881
KCNN4	-8688	-9381	3192	781	5477
KCNQ4	-5548	-8834	-301	-1001	3880
KCNQ5	-486	-1727	-1858	7587	7815
KCNS1	724	27	-2810	7547	7686
KIF17	-1489	-1198	2947	8037	8202
KPNA2	-7476	-5242	4362	3922	198
KRAS	-3001	-89	138	-784	-790
LIN7B	-4201	-998	-741	4	4069
LIN7C	-2622	-5235	606	1159	2749
LRFN3	344	-2198	3046	6943	1660
LRFN4	-4820	-7290	6309	666	-935
LRTOMT	-1885	-1809	2195	4253	5836
MAPK1	-2717	-2873	-1146	3217	-292
MAPK3	-6889	-9407	-1492	8081	6172
MAPT	-2959	-1119	201	2894	5154
MDM2	-7427	-3880	5322	1489	4370
MYO6	-7358	-4785	1092	1272	2167
NAAA	-105	-6523	1733	6369	3567
NBEA	601	-1104	-1866	1043	-263
NCALD	-1283	246	1257	6191	-463
NPTN	-427	-911	894	-34	2511
NRGN	-6866	-2345	776	6581	2683
PANX1	-6109	-8850	3389	3675	1891
PDLIM5	-720	-1534	384	4832	7187
PDPK1	-6239	-376	3800	444	2190
PICK1	-4324	-7918	-471	7317	2998
PLCB2	-9002	-6406	1115	-912	-362
PLCB3	-1778	-7628	-1041	-1010	195
PPFIA1	-6805	-7176	-600	-850	1099
PPFIA3	-767	-1784	-1864	4437	2905
PPFIBP1	-8197	-6906	5366	1797	5909
PPFIBP2	-3250	-7873	-2943	2878	7529
PPM1F	-2561	-5038	-1585	302	4984
PRKAA1	-4171	-954	-1152	5406	5062
PRKAB1	-6437	-4951	5662	-167	1351
PRKAB2	-3725	-7118	1621	5427	2154
PRKACA	-4718	-4025	-1287	480	3795
PRKACB	-6646	-908	2348	1167	1023
PRKAG1	-6626	-8822	4778	-622	4636
PRKAG2	-4216	-7353	4444	8	3106
PRKAR1A	-7139	-2501	4900	-147	424
PRKAR1B	-265	-107	-3015	7076	7451
PRKAR2A	-825	-2422	-2557	771	3315
PRKCA	-5820	-4955	3971	3486	5016
PRKCB	-8182	-7652	5627	-1153	-988
RAB3A	-328	-4284	-2441	7362	8353
RAC1	-2096	-4182	1706	2583	1143
RPS6KA1	-5437	-3891	-2723	-627	1954
RPS6KA2	-5884	-402	3112	3010	3312
RTN3	-3546	-3266	-895	4155	824
SHARPIN	-3207	-7682	818	3369	3405
SLC1A1	-1311	-9400	-2572	2485	6519
SLC38A1	-8185	-6587	6458	164	-795
SLC38A2	-4922	-7248	677	1883	6714
SRC	-5098	-8229	-427	-41	-814
STX1A	-4435	-985	1081	-249	515
STXBP1	-7426	-6845	1842	5676	8139
UNC13B	-750	-1126	-1692	4975	6694
VAMP2	-4164	-4621	543	2158	382

---

---

Major pathway of rRNA processing in the nucleolus and cytosol

Major pathway of rRNA processing in the nucleolus and cytosol

metric	value
setSize	140
pMANOVA	2.73e-05
p.adjustMANOVA	0.00239
s.dist	0.28
s.psf	0.017
s.psb	-0.117
s.hcy	0.0733
s.folate	0.158
s.vitb12	0.185
p.psf	0.73
p.psb	0.0173
p.hcy	0.136
p.folate	0.00127
p.vitb12	0.000166

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	vitb12	folate
CSNK1E	8577	7983
RPS27A	8264	8228
RPS24	8504	7985
PES1	8026	8341
RPSA	8168	8071
RPL15	8423	7772
RPL34	8213	7954
UTP20	8426	7701
RIOK2	8233	7755
RPS25	7689	8288
RPL28	8337	7634
RPL9	8503	7462
RPS28	7739	8167
C1D	8248	7585
BYSL	8099	7563
DDX52	8105	7367
UTP6	8055	7403
DDX47	6894	8287
RPL41	7829	7287
RPS6	6880	8168

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
BMS1	-2776	-2778	-2326	3878	2450
BYSL	-4178	-9536	6111	7563	8099
C1D	-3010	-6362	1064	7585	8248
CSNK1D	-973	-7670	2239	1107	4901
CSNK1E	614	-3165	-729	7983	8577
DCAF13	-5830	-1699	3821	6595	7638
DDX21	-5888	-3897	3188	3469	6682
DDX47	334	-4037	-1806	8287	6894
DDX49	-4822	-5792	5371	-412	788
DDX52	-4300	-7923	2602	7367	8105
DHX37	-7569	-4973	5147	689	58
DIS3	-8552	-9237	3964	2928	1121
EBNA1BP2	-8700	-8946	1196	3873	5515
ERI1	-6742	-8109	4581	-851	-677
EXOSC10	-1296	-2277	1561	7129	5838
EXOSC2	-8729	-9244	2530	3525	4504
EXOSC3	-1149	-6526	748	501	4842
EXOSC4	-5949	-971	3231	1277	-86
EXOSC5	-6533	-4703	1943	-485	-100
EXOSC6	-1630	-2864	1276	6042	4034
EXOSC7	-8091	-8183	3484	4662	6982
EXOSC8	-8053	-4017	6064	3443	6272
FAU	-7265	-3975	4740	233	1443
FBL	-1016	-3458	-2129	7793	7043
FCF1	-388	-3791	-123	6479	8244
FTSJ3	-6448	-1225	-1655	4146	6605
GNL3	-2576	-2510	3435	216	3410
HEATR1	-4869	-3287	2084	3939	6174
IMP3	-6465	-6229	388	4395	4138
IMP4	-1644	-5137	-220	5827	4713
ISG20L2	-7334	-1485	5735	997	-952
LTV1	-4883	-1561	662	6380	6318
MPHOSPH10	-8327	-4667	4534	1092	-150
MPHOSPH6	-4444	-3883	2630	6246	6385
NCL	-5736	-2460	2823	872	2137
NIP7	-8733	-7995	4984	820	-21
NOB1	-1208	-2611	-131	4405	4604
NOC4L	-6156	-4743	-1501	665	502
NOL11	-4583	-2640	2367	3213	3045
NOL12	-8329	-7236	2920	4088	7991
NOL6	-7508	-8624	-40	4802	4970
NOP14	649	185	3743	2648	-494
NOP56	-5280	-7733	2511	1724	4467
NOP58	-8048	-1193	4754	1322	6909
PDCD11	-2614	-3039	1969	4218	1847
PELP1	-4092	-3704	3720	4290	5506
PES1	-2938	-8904	-2265	8341	8026
PNO1	-3481	-5763	266	5053	4129
PWP2	-7581	-2679	4980	608	-496
RBM28	-492	-4862	-522	3026	7719
RCL1	-4719	-6386	-1205	8222	2198
RIOK1	-869	-7955	-497	2384	8560
RIOK2	-4653	-8102	2370	7755	8233
RIOK3	-6720	-3909	348	1192	5569
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPP14	-6182	-3689	2495	7012	4934
RPP21	-4699	-6536	906	1823	4298
RPP25	-4651	-7431	-2548	991	3559
RPP30	-4130	-8638	3731	7603	7125
RPP38	-6757	-3693	5497	823	-465
RPP40	-7953	-7432	5100	-457	-660
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
RRP1	-4052	-2434	-355	1248	3362
RRP7A	-434	-3767	-483	5962	7569
RRP9	-6069	-5735	5668	1022	3846
SENP3	517	-4315	-2379	4693	3631
TBL3	-6351	-4910	3907	5814	1166
TEX10	-3423	-3222	3700	1160	6096
TSR1	-401	-7858	-615	1421	8087
UBA52	-513	-1242	1530	5448	5828
UTP15	-4172	-8340	2250	4993	5787
UTP20	-4309	-9369	1726	7701	8426
UTP3	-7407	-6686	4792	4201	2357
UTP6	-1554	-7039	-1982	7403	8055
WBSCR22	-804	-282	-787	7872	6653
WDR12	-2331	-8402	-1014	5442	8152
WDR18	-4202	-6937	-1636	7463	5776
WDR3	-3894	-2871	5316	1443	5073
WDR36	-4315	-1996	3648	2073	4211
WDR43	-7910	-5699	6105	5052	858
WDR75	-4477	-8608	3688	7541	7194
XRN2	-1731	-7300	2453	2897	4923

---

---

Mitotic Anaphase

Mitotic Anaphase

metric	value
setSize	185
pMANOVA	3e-05
p.adjustMANOVA	0.00245
s.dist	0.226
s.psf	-0.0269
s.psb	-0.0493
s.hcy	0.0943
s.folate	0.165
s.vitb12	0.108
p.psf	0.53
p.psb	0.25
p.hcy	0.0278
p.folate	0.000113
p.vitb12	0.0116

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
ZWILCH	8324	8308
RPS27A	8228	8264
NUP35	8140	8243
CDC23	8244	8117
CCNB2	7856	8479
PSMA3	8188	7955
NUP107	8020	7981
SPC25	8021	7791
SKA2	8095	7700
PSMB5	7598	7952
UBB	7418	8036
CDCA8	7190	8272
VRK2	8002	7219
PSMD12	7015	7973
NUP98	7764	7066
RAD21	7352	7315
RAN	7323	7330
CHMP6	7662	6991
RANGAP1	7332	7247
PSMB7	6667	7933

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
AHCTF1	-958	-5776	-1162	5566	2735
ANAPC1	-4888	-4370	4561	5142	1218
ANAPC10	-404	-8610	-361	6447	2473
ANAPC11	-1837	-244	601	4297	4855
ANAPC2	-5187	-4944	5252	-135	-940
ANAPC4	-1773	-8700	4698	4531	5293
ANAPC5	-2266	-8728	1095	6000	7040
ANAPC7	-3940	-8396	2305	7272	5608
ANKLE2	-2924	-731	-8	-905	1706
APITD1	-7436	-4833	3086	-1142	-173
AURKB	-5215	-5327	5907	4882	2882
B9D2	-6812	-1761	3803	2128	3929
BANF1	-4278	-7582	1929	7554	3391
BIRC5	-5343	-8595	2843	5224	6417
BUB1	-5409	-7034	-1899	3149	4435
BUB1B	-7490	-8066	1793	6952	3147
BUB3	-1044	-2492	-425	6580	5165
CC2D1B	-2209	-5632	4256	2926	244
CCNB1	-8633	-4816	6272	-1067	-816
CCNB2	-6798	-5895	4682	7856	8479
CDC16	-1108	-909	-2388	2815	1317
CDC20	-212	-931	-491	6613	4602
CDC23	-1180	-4858	84	8244	8117
CDCA5	-1121	-417	3175	3307	5915
CDCA8	-4157	-4002	538	7190	8272
CDK1	-3517	-5019	2450	2546	7363
CENPA	-5443	-3670	4463	-64	856
CENPE	-2106	-3196	899	5698	6188
CENPF	552	-58	5351	4636	6138
CENPH	-166	-3676	-1863	7000	5510
CENPK	-7596	-7798	2332	7331	3303
CENPL	-5982	-8049	2744	3755	4081
CENPM	-3068	-1127	3488	4808	3710
CENPN	-7748	-8268	3464	2589	1857
CENPO	-4585	-5217	2243	6228	3869
CENPP	-8987	-5989	4188	-475	-375
CENPQ	-5168	-8986	788	4612	6598
CENPT	-2887	-4406	2029	313	2718
CHMP2A	-4412	-5990	3751	6470	5425
CHMP2B	-1760	-5679	1172	4483	2940
CHMP4A	-8629	-6757	3557	2746	6097
CHMP4B	35	-2199	-830	6687	7422
CHMP6	-41	-3642	638	7662	6991
CHMP7	-5810	-147	4685	1840	4961
CKAP5	-4894	-8730	4720	1363	835
CLASP1	-5095	-5549	1549	5253	6532
CLASP2	-5060	-3223	-1727	6396	6132
CLIP1	-5995	-5664	2164	-399	4405
DSN1	-2102	-4234	3232	2568	3430
DYNC1H1	-4365	-3256	5029	425	786
DYNC1I2	-6567	-7070	2439	2184	2874
DYNC1LI1	-5010	-1342	2070	1660	915
DYNC1LI2	-3958	-1793	-456	881	-232
DYNLL1	-6435	-1692	4607	677	956
DYNLL2	-1210	-5926	4788	4965	6455
ESPL1	-5611	-8871	2600	5459	8069
INCENP	-4410	-8460	5832	4041	3256
ITGB3BP	-1579	-8699	-2272	7906	4726
KIF18A	-8597	-7811	5152	1274	-189
KIF2A	-1404	-1285	1265	7884	1754
KIF2C	-5335	-4400	4652	5934	7164
KNTC1	-4087	-2381	-2217	7127	5117
KPNB1	-6642	-3659	4322	363	1576
LBR	-6739	-8663	5971	1829	5800
LEMD2	-7011	-9314	5022	6806	1314
LEMD3	-2955	-5799	2330	3740	7474
LMNA	514	-8510	-2632	4679	3620
LMNB1	-7257	-5018	3817	4000	853
MAD1L1	-2169	-893	4397	1233	2279
MAD2L1	-693	-4252	1421	6862	6842
MAPRE1	-6287	-7647	-1239	6750	6392
MIS12	-5040	-5098	3865	137	2565
NDC80	-7727	-3732	4054	3903	88
NDE1	-7104	-8550	191	5467	7621
NDEL1	-3675	-1775	5672	-63	2872
NSL1	-7171	-7994	4556	6255	5553
NUDC	-5765	-4788	5046	1526	3072
NUF2	-4503	-7059	-2397	6976	4190
NUP107	-2367	-5920	902	8020	7981
NUP133	-2192	-6208	-1034	6710	4350
NUP155	-938	-2261	778	3101	6606
NUP160	-4062	-2126	-1133	5658	7516
NUP188	-4111	-2994	3510	3714	3909
NUP205	-8245	-8394	4686	6267	6798
NUP35	-1551	-7219	-1373	8140	8243
NUP37	-7550	-421	4573	1438	1480
NUP43	-5408	-4131	4558	2582	2522
NUP54	-1931	-4958	3515	3754	3208
NUP62	-1453	-8038	1978	7023	5407
NUP85	-7303	-8224	5526	3668	1520
NUP93	-3267	-3790	-2168	3175	6994
NUP98	-8199	-889	2149	7764	7066
PAFAH1B1	-5211	-2836	5904	687	-129
PDS5A	-8750	-3459	6341	166	2013
PDS5B	-8826	-3671	4713	-583	3187
PLK1	-4551	-1935	-118	2868	3399
PMF1	-8472	-8813	4661	3508	5960
POM121	-6127	-7922	5593	4069	6325
PPP1CC	383	-760	-109	3143	1760
PPP2CA	-4081	-3471	4425	2847	2701
PPP2CB	-1353	77	5390	-624	-872
PPP2R1B	-1840	-3560	3568	7877	5301
PPP2R2A	-144	-5849	1125	5472	6709
PPP2R5A	-7527	-7188	1532	3085	360
PPP2R5B	-4467	-4603	1078	4371	2363
PPP2R5C	-3793	-9136	3153	2104	6783
PPP2R5D	-2176	-6920	-2111	6390	7682
PPP2R5E	-551	-1739	863	6882	7627
PSMA1	-8359	-8604	5104	1855	4650
PSMA2	-7938	-2161	5110	1432	8018
PSMA3	-2004	-4530	4184	8188	7955
PSMA5	-3753	-5163	4135	7049	6792
PSMA6	-5756	-9052	230	3273	5895
PSMA7	-5963	-1772	3526	2927	3736
PSMB1	-2258	-1758	1218	4974	2620
PSMB10	-1663	-6710	-165	6829	6594
PSMB3	-3839	-6905	4780	5497	4412
PSMB5	-89	-6668	-1101	7598	7952
PSMB6	-6634	-5888	2326	6558	5006
PSMB7	-5105	-6476	-481	6667	7933
PSMB8	-7792	-3686	5160	756	1587
PSMB9	-8032	-7032	4898	3199	1447
PSMC1	89	-6196	611	7227	6270
PSMC3	-4234	-5168	-1757	3247	5525
PSMC4	-5962	-6708	1563	2130	2138
PSMC5	-7766	-7267	5418	2470	428
PSMC6	-7087	-7964	4301	5996	2878
PSMD1	-1790	-8089	458	4661	6182
PSMD11	-1272	-2207	4285	6544	4390
PSMD12	-2535	-3717	20	7015	7973
PSMD13	-8546	-5774	4927	2662	-882
PSMD14	-2548	-5579	3518	3709	4574
PSMD2	-7305	-6402	3485	3621	4835
PSMD3	-6151	-6416	5506	2545	2496
PSMD4	-7964	-5567	754	5325	7149
PSMD6	-4518	-717	1908	2403	114
PSMD7	-3120	-8646	2963	5075	5520
PSMD8	-4369	-5263	1397	3011	5309
PSMD9	-1075	-5374	3215	4605	1840
PSME1	-4828	-2498	2379	209	820
PSME2	-3988	-5227	2344	6844	5159
PSME3	-502	-1677	210	3994	6092
PSME4	-4990	-8991	5997	207	-839
PSMF1	-490	-5529	-2618	4670	8624
PTTG1	-6300	-7345	144	7353	5706
RAD21	-6823	-6698	-54	7352	7315
RAN	215	-1000	-1174	7323	7330
RANBP2	-3530	-4429	-1283	4903	6045
RANGAP1	-1482	-1294	-174	7332	7247
RCC1	-8899	-1220	6472	4803	-1137
RCC2	-4789	-1909	3142	1194	346
RPS27A	-6317	-9335	373	8228	8264
SEC13	-8747	-6731	4873	-516	1432
SEH1L	-7723	-5493	4691	844	4470
SIRT2	-3680	-1049	5840	3829	3363
SKA2	-9013	-5218	2224	8095	7700
SMC3	-5441	-8998	4416	6498	3310
SPAST	-7900	-8245	4541	1651	2766
SPC24	-4560	-3857	1317	4230	1955
SPC25	-2804	-6663	-1447	8021	7791
STAG1	-6618	-7770	5829	5087	5078
SUMO1	-1344	-2879	-2075	6159	7290
TAOK1	-5074	-852	6421	1847	383
TMPO	-1	-178	629	4115	1507
TNPO1	-3433	-5362	5407	2469	4010
TUBA1A	-3868	-6814	281	7982	5851
TUBA1B	-2586	-3957	1859	3184	4585
TUBA1C	-3611	-1926	3980	5273	1821
TUBA4A	-2725	-3627	757	7569	1248
TUBA4B	-8730	-3132	6556	-578	-182
TUBB2A	-1141	-1970	-2479	3793	3564
UBA52	-513	-1242	1530	5448	5828
UBB	-6553	-5964	-13	7418	8036
UBC	-8288	-7011	-1067	5810	7639
UBE2C	-759	-2829	-1688	6275	6660
UBE2D1	-2809	-3007	-157	1866	1336
UBE2E1	-4493	-4384	-1323	3040	2903
UBE2I	-3937	-1487	5265	-28	148
VPS4A	-3975	-2950	2335	4622	5426
VRK1	-4206	-3102	4985	6441	4404
VRK2	-2498	-7336	-1683	8002	7219
XPO1	-6677	-4338	4933	4303	2828
ZW10	-3358	-4465	-133	4675	7777
ZWILCH	-1670	-8800	-1593	8324	8308
ZWINT	-4132	-4213	2506	5868	2166

---

---

Transmission across Chemical Synapses

Transmission across Chemical Synapses

metric	value
setSize	93
pMANOVA	4.58e-05
p.adjustMANOVA	0.00349
s.dist	0.302
s.psf	0.076
s.psb	0.125
s.hcy	-0.23
s.folate	-0.116
s.vitb12	-0.0546
p.psf	0.206
p.psb	0.0369
p.hcy	0.00013
p.folate	0.0538
p.vitb12	0.364

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	hcy	psb
GRIN1	-2485	71

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
ABAT	-5243	-1324	-2789	1692	585
ADCY4	-4326	-2533	-1935	377	-183
ADCY7	-8384	-9239	-2990	-609	4432
ADCY9	-8670	-84	2546	2727	-326
ALDH5A1	-2246	-5305	297	2302	3311
AP2A1	-8799	-6898	4882	1998	207
AP2M1	-2247	-892	-611	4902	5257
AP2S1	-5172	-4343	-2469	8169	8393
APBA1	-2203	-6452	-1859	4747	3277
ARHGEF7	-2889	-963	1038	6761	5725
ARL6IP5	-2946	-8504	-1851	7924	7238
CACNA2D2	-4793	-7194	3989	4081	5292
CALM1	-1140	-3090	-703	2569	5919
CAMK1	622	-1001	-2658	4883	-605
CAMK2D	-7602	-2920	6135	-628	-174
CAMK2G	-250	-62	-829	6968	1605
CAMK4	-258	-3558	2726	1835	284
CAMKK1	-5757	-5738	4543	-336	2542
CAMKK2	-3279	-6235	-2051	293	4332
CHRNA5	-6551	-6847	853	-985	304
CHRNB4	-999	-566	6666	-507	2037
CHRNE	390	-210	-2588	6007	6055
COMT	-7446	-9092	-1986	8218	7820
CREB1	-4159	-1226	472	-273	3361
DLG1	-385	-1091	2874	5485	1201
DLG4	-1757	-7935	-1172	5776	4723
DNAJC5	-484	-54	-2896	3436	7899
GABBR1	-539	-7192	-2447	2909	7972
GIT1	443	-5279	-3090	718	4910
GLS	-6017	-3405	-61	7562	3560
GLUL	-8463	-7643	-3101	8124	8084
GNAI2	-3270	-4506	1325	3664	3728
GNAI3	-4256	-6373	1076	7816	7566
GNAL	-5039	-3815	4412	4827	6369
GNB1	-7545	-2084	-2592	-1002	-473
GNB2	-6564	-4671	4217	2806	1836
GNB4	-5727	-7860	355	1400	5628
GNB5	-5029	-2955	2913	6045	4939
GNG12	-9078	-8896	6415	-1213	6604
GNG2	454	-690	4308	7887	6859
GNG4	682	214	2653	6944	7223
GNG5	-285	-98	3683	7410	108
GRIN1	244	71	-2485	1161	-555
GRIN2C	-810	-8353	-2408	-394	3376
GRIN2D	-1104	-8108	-2134	1042	7433
HRAS	348	-304	-2761	2241	5443
KIF17	-1489	-1198	2947	8037	8202
KPNA2	-7476	-5242	4362	3922	198
KRAS	-3001	-89	138	-784	-790
LIN7B	-4201	-998	-741	4	4069
LIN7C	-2622	-5235	606	1159	2749
LRTOMT	-1885	-1809	2195	4253	5836
MAPK1	-2717	-2873	-1146	3217	-292
MAPK3	-6889	-9407	-1492	8081	6172
MAPT	-2959	-1119	201	2894	5154
MDM2	-7427	-3880	5322	1489	4370
MYO6	-7358	-4785	1092	1272	2167
NAAA	-105	-6523	1733	6369	3567
NBEA	601	-1104	-1866	1043	-263
NCALD	-1283	246	1257	6191	-463
NPTN	-427	-911	894	-34	2511
NRGN	-6866	-2345	776	6581	2683
PDPK1	-6239	-376	3800	444	2190
PICK1	-4324	-7918	-471	7317	2998
PLCB2	-9002	-6406	1115	-912	-362
PLCB3	-1778	-7628	-1041	-1010	195
PPFIA1	-6805	-7176	-600	-850	1099
PPFIA3	-767	-1784	-1864	4437	2905
PPM1F	-2561	-5038	-1585	302	4984
PRKAA1	-4171	-954	-1152	5406	5062
PRKAB1	-6437	-4951	5662	-167	1351
PRKAB2	-3725	-7118	1621	5427	2154
PRKACA	-4718	-4025	-1287	480	3795
PRKACB	-6646	-908	2348	1167	1023
PRKAG1	-6626	-8822	4778	-622	4636
PRKAG2	-4216	-7353	4444	8	3106
PRKAR1A	-7139	-2501	4900	-147	424
PRKAR1B	-265	-107	-3015	7076	7451
PRKAR2A	-825	-2422	-2557	771	3315
PRKCA	-5820	-4955	3971	3486	5016
PRKCB	-8182	-7652	5627	-1153	-988
RAB3A	-328	-4284	-2441	7362	8353
RAC1	-2096	-4182	1706	2583	1143
RPS6KA1	-5437	-3891	-2723	-627	1954
RPS6KA2	-5884	-402	3112	3010	3312
SLC1A1	-1311	-9400	-2572	2485	6519
SLC38A1	-8185	-6587	6458	164	-795
SLC38A2	-4922	-7248	677	1883	6714
SRC	-5098	-8229	-427	-41	-814
STX1A	-4435	-985	1081	-249	515
STXBP1	-7426	-6845	1842	5676	8139
UNC13B	-750	-1126	-1692	4975	6694
VAMP2	-4164	-4621	543	2158	382

---

---

Neurotransmitter receptors and postsynaptic signal transmission

Neurotransmitter receptors and postsynaptic signal transmission

metric	value
setSize	73
pMANOVA	8.46e-05
p.adjustMANOVA	0.00552
s.dist	0.348
s.psf	0.0826
s.psb	0.18
s.hcy	-0.182
s.folate	-0.181
s.vitb12	-0.124
p.psf	0.223
p.psb	0.00801
p.hcy	0.00715
p.folate	0.00749
p.vitb12	0.0665

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	hcy	folate
GNB1	-2592	-1002
ADCY7	-2990	-609
RPS6KA1	-2723	-627
PLCB3	-1041	-1010
GRIN2C	-2408	-394
SRC	-427	-41

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
ADCY4	-4326	-2533	-1935	377	-183
ADCY7	-8384	-9239	-2990	-609	4432
ADCY9	-8670	-84	2546	2727	-326
AP2A1	-8799	-6898	4882	1998	207
AP2M1	-2247	-892	-611	4902	5257
AP2S1	-5172	-4343	-2469	8169	8393
APBA1	-2203	-6452	-1859	4747	3277
ARHGEF7	-2889	-963	1038	6761	5725
CALM1	-1140	-3090	-703	2569	5919
CAMK1	622	-1001	-2658	4883	-605
CAMK2D	-7602	-2920	6135	-628	-174
CAMK2G	-250	-62	-829	6968	1605
CAMK4	-258	-3558	2726	1835	284
CAMKK1	-5757	-5738	4543	-336	2542
CAMKK2	-3279	-6235	-2051	293	4332
CHRNA5	-6551	-6847	853	-985	304
CHRNB4	-999	-566	6666	-507	2037
CHRNE	390	-210	-2588	6007	6055
CREB1	-4159	-1226	472	-273	3361
DLG1	-385	-1091	2874	5485	1201
DLG4	-1757	-7935	-1172	5776	4723
GABBR1	-539	-7192	-2447	2909	7972
GIT1	443	-5279	-3090	718	4910
GNAI2	-3270	-4506	1325	3664	3728
GNAI3	-4256	-6373	1076	7816	7566
GNAL	-5039	-3815	4412	4827	6369
GNB1	-7545	-2084	-2592	-1002	-473
GNB2	-6564	-4671	4217	2806	1836
GNB4	-5727	-7860	355	1400	5628
GNB5	-5029	-2955	2913	6045	4939
GNG12	-9078	-8896	6415	-1213	6604
GNG2	454	-690	4308	7887	6859
GNG4	682	214	2653	6944	7223
GNG5	-285	-98	3683	7410	108
GRIN1	244	71	-2485	1161	-555
GRIN2C	-810	-8353	-2408	-394	3376
GRIN2D	-1104	-8108	-2134	1042	7433
HRAS	348	-304	-2761	2241	5443
KIF17	-1489	-1198	2947	8037	8202
KPNA2	-7476	-5242	4362	3922	198
KRAS	-3001	-89	138	-784	-790
LIN7B	-4201	-998	-741	4	4069
LIN7C	-2622	-5235	606	1159	2749
MAPK1	-2717	-2873	-1146	3217	-292
MAPK3	-6889	-9407	-1492	8081	6172
MAPT	-2959	-1119	201	2894	5154
MDM2	-7427	-3880	5322	1489	4370
MYO6	-7358	-4785	1092	1272	2167
NBEA	601	-1104	-1866	1043	-263
NCALD	-1283	246	1257	6191	-463
NPTN	-427	-911	894	-34	2511
NRGN	-6866	-2345	776	6581	2683
PDPK1	-6239	-376	3800	444	2190
PICK1	-4324	-7918	-471	7317	2998
PLCB2	-9002	-6406	1115	-912	-362
PLCB3	-1778	-7628	-1041	-1010	195
PPM1F	-2561	-5038	-1585	302	4984
PRKAA1	-4171	-954	-1152	5406	5062
PRKAB1	-6437	-4951	5662	-167	1351
PRKAB2	-3725	-7118	1621	5427	2154
PRKACA	-4718	-4025	-1287	480	3795
PRKACB	-6646	-908	2348	1167	1023
PRKAG1	-6626	-8822	4778	-622	4636
PRKAG2	-4216	-7353	4444	8	3106
PRKAR1A	-7139	-2501	4900	-147	424
PRKAR1B	-265	-107	-3015	7076	7451
PRKAR2A	-825	-2422	-2557	771	3315
PRKCA	-5820	-4955	3971	3486	5016
PRKCB	-8182	-7652	5627	-1153	-988
RAC1	-2096	-4182	1706	2583	1143
RPS6KA1	-5437	-3891	-2723	-627	1954
RPS6KA2	-5884	-402	3112	3010	3312
SRC	-5098	-8229	-427	-41	-814

---

---

Signaling by ROBO receptors

Signaling by ROBO receptors

metric	value
setSize	146
pMANOVA	8.55e-05
p.adjustMANOVA	0.00552
s.dist	0.257
s.psf	0.0143
s.psb	-0.111
s.hcy	0.0853
s.folate	0.159
s.vitb12	0.144
p.psf	0.767
p.psb	0.0209
p.hcy	0.0764
p.folate	0.000979
p.vitb12	0.00274

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
NCBP1	8402	8509
ABL2	8234	8399
RPS27A	8228	8264
RPS24	7985	8504
RPSA	8071	8168
RPL15	7772	8423
RPL34	7954	8213
PSMA3	8188	7955
RPS25	8288	7689
RPL28	7634	8337
RPL9	7462	8503
RPS28	8167	7739
PSMB5	7598	7952
UBB	7418	8036
RPL41	7287	7829
RPS6	8168	6880
PFN2	8238	6818
PSMD12	7015	7973
RPL32	6861	8038
RPL37A	6591	8046

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
ABL1	-5509	-7422	-538	5899	4752
ABL2	-3063	-4181	-712	8234	8399
CAP1	-5073	-4995	2598	6176	2691
CASC3	-5894	-3543	-120	2750	7789
CDC42	-8344	-5040	6439	-1172	-650
CLASP1	-5095	-5549	1549	5253	6532
CLASP2	-5060	-3223	-1727	6396	6132
CUL2	-6279	-4347	4648	4094	359
CXCR4	-6235	-8952	-1826	2548	5533
DAG1	-5529	-8643	-1037	1109	-387
EIF4A3	-1889	-241	4502	5779	4014
EIF4G1	-2868	-940	4004	1882	-227
ETF1	-5256	-1911	4663	-25	4397
EVL	-1573	-983	3039	4872	2774
FAU	-7265	-3975	4740	233	1443
GSPT1	-2286	-956	-604	2009	-353
LDB1	-2901	-6560	2875	5453	5999
MYO9B	-6299	-3100	4169	1112	4917
NCBP1	-2607	-1945	2448	8402	8509
NCBP2	-3917	-5147	2973	6756	7623
NCK1	-5828	-8064	1491	3798	2501
NCK2	-4373	-2127	2800	1297	981
NTN1	577	-458	5523	5763	8218
PABPC1	-3400	-5506	4238	5582	1293
PAK1	-1779	-3827	-1898	2913	1739
PAK2	-8956	-7479	359	5230	5358
PAK4	-3032	-4587	-2307	7768	6717
PFN1	-4949	-6276	3462	1516	7487
PFN2	-6336	-9158	-2924	8238	6818
PPP3CB	-4512	-6520	2798	5366	5491
PRKACA	-4718	-4025	-1287	480	3795
PRKACB	-6646	-908	2348	1167	1023
PRKAR2A	-825	-2422	-2557	771	3315
PRKCA	-5820	-4955	3971	3486	5016
PSMA1	-8359	-8604	5104	1855	4650
PSMA2	-7938	-2161	5110	1432	8018
PSMA3	-2004	-4530	4184	8188	7955
PSMA5	-3753	-5163	4135	7049	6792
PSMA6	-5756	-9052	230	3273	5895
PSMA7	-5963	-1772	3526	2927	3736
PSMB1	-2258	-1758	1218	4974	2620
PSMB10	-1663	-6710	-165	6829	6594
PSMB3	-3839	-6905	4780	5497	4412
PSMB5	-89	-6668	-1101	7598	7952
PSMB6	-6634	-5888	2326	6558	5006
PSMB7	-5105	-6476	-481	6667	7933
PSMB8	-7792	-3686	5160	756	1587
PSMB9	-8032	-7032	4898	3199	1447
PSMC1	89	-6196	611	7227	6270
PSMC3	-4234	-5168	-1757	3247	5525
PSMC4	-5962	-6708	1563	2130	2138
PSMC5	-7766	-7267	5418	2470	428
PSMC6	-7087	-7964	4301	5996	2878
PSMD1	-1790	-8089	458	4661	6182
PSMD11	-1272	-2207	4285	6544	4390
PSMD12	-2535	-3717	20	7015	7973
PSMD13	-8546	-5774	4927	2662	-882
PSMD14	-2548	-5579	3518	3709	4574
PSMD2	-7305	-6402	3485	3621	4835
PSMD3	-6151	-6416	5506	2545	2496
PSMD4	-7964	-5567	754	5325	7149
PSMD6	-4518	-717	1908	2403	114
PSMD7	-3120	-8646	2963	5075	5520
PSMD8	-4369	-5263	1397	3011	5309
PSMD9	-1075	-5374	3215	4605	1840
PSME1	-4828	-2498	2379	209	820
PSME2	-3988	-5227	2344	6844	5159
PSME3	-502	-1677	210	3994	6092
PSME4	-4990	-8991	5997	207	-839
PSMF1	-490	-5529	-2618	4670	8624
RAC1	-2096	-4182	1706	2583	1143
RBX1	-8553	-7492	5617	651	240
RHOA	-8293	-3660	4371	2719	5343
RNPS1	-5625	-5883	3685	2173	1138
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
SLIT1	644	-9593	-2979	-672	8416
SOS2	-241	-4186	6197	7347	5212
SRC	-5098	-8229	-427	-41	-814
SRGAP1	-900	-7665	-2646	3456	4523
SRGAP3	-4587	-7500	-2085	586	2673
UBA52	-513	-1242	1530	5448	5828
UBB	-6553	-5964	-13	7418	8036
UBC	-8288	-7011	-1067	5810	7639
UPF2	-4419	-6130	3206	2503	1382
UPF3A	-4731	-2250	5839	2172	4276
USP33	-3204	-3393	4583	6511	4700
VASP	-5209	-6570	3762	3146	2933

---

---

Selenocysteine synthesis

Selenocysteine synthesis

metric	value
setSize	65
pMANOVA	8.71e-05
p.adjustMANOVA	0.00552
s.dist	0.383
s.psf	0.111
s.psb	-0.142
s.hcy	0.0997
s.folate	0.251
s.vitb12	0.203
p.psf	0.123
p.psb	0.0479
p.hcy	0.165
p.folate	0.000477
p.vitb12	0.0048

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
RPS27A	8228	8264
RPS24	7985	8504
RPSA	8071	8168
RPL15	7772	8423
RPL34	7954	8213
RPS25	8288	7689
RPL28	7634	8337
RPL9	7462	8503
RPS28	8167	7739
EEFSEC	7576	8082
RPL41	7287	7829
RPS6	8168	6880
RPL32	6861	8038
RPL37A	6591	8046
RPS16	6351	8153
RPL23	6505	7202
RPS23	6550	6652
RPL26L1	7153	5923
RPS29	5166	7494
RPL22	5041	7376

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
EEFSEC	-1292	-1338	941	7576	8082
FAU	-7265	-3975	4740	233	1443
PSTK	-5041	-8997	-2776	3968	4483
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
SEPHS2	-2816	-7771	-1308	4943	6367
UBA52	-513	-1242	1530	5448	5828

---

---

Peptide chain elongation

Peptide chain elongation

metric	value
setSize	64
pMANOVA	9.32e-05
p.adjustMANOVA	0.00559
s.dist	0.372
s.psf	0.113
s.psb	-0.106
s.hcy	0.126
s.folate	0.244
s.vitb12	0.198
p.psf	0.118
p.psb	0.145
p.hcy	0.0807
p.folate	0.00075
p.vitb12	0.00628

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
RPS27A	8228	8264
RPS24	7985	8504
RPSA	8071	8168
RPL15	7772	8423
RPL34	7954	8213
RPS25	8288	7689
RPL28	7634	8337
RPL9	7462	8503
RPS28	8167	7739
RPL41	7287	7829
RPS6	8168	6880
RPL32	6861	8038
RPL37A	6591	8046
RPS16	6351	8153
RPL23	6505	7202
RPS23	6550	6652
RPL26L1	7153	5923
RPS29	5166	7494
EEF2	5988	6454
RPL22	5041	7376

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
EEF1A1	-3918	-942	2202	3605	6293
EEF2	-875	-295	765	5988	6454
FAU	-7265	-3975	4740	233	1443
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
UBA52	-513	-1242	1530	5448	5828

---

---

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

metric	value
setSize	81
pMANOVA	0.000117
p.adjustMANOVA	0.00617
s.dist	0.304
s.psf	0.0975
s.psb	-0.0563
s.hcy	0.149
s.folate	0.202
s.vitb12	0.13
p.psf	0.13
p.psb	0.382
p.hcy	0.021
p.folate	0.0017
p.vitb12	0.0442

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	hcy
RPL4	8137	3711
RPL41	7287	4115
RPL3	7916	3364
RPL29	5290	4990
EIF4A3	5779	4502
PABPC1	5582	4238
RPS10	5908	3900
RPS29	5166	4263
RPS27L	4151	5057
RPL23	6505	3169
NCBP1	8402	2448
RPL31	3555	5771
NCBP2	6756	2973
RPS28	8167	2374
RPS3	8185	2229
RPS6	8168	2203
RPS3A	4514	3771
RPL37	6405	2639
RPL32	6861	2458
RPL11	4330	3810

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
CASC3	-5894	-3543	-120	2750	7789
DCP1A	-4668	-4529	1204	4837	3403
EIF4A3	-1889	-241	4502	5779	4014
EIF4G1	-2868	-940	4004	1882	-227
ETF1	-5256	-1911	4663	-25	4397
FAU	-7265	-3975	4740	233	1443
GSPT1	-2286	-956	-604	2009	-353
NCBP1	-2607	-1945	2448	8402	8509
NCBP2	-3917	-5147	2973	6756	7623
PABPC1	-3400	-5506	4238	5582	1293
PNRC2	-4158	-6285	2483	96	54
PPP2CA	-4081	-3471	4425	2847	2701
PPP2R2A	-144	-5849	1125	5472	6709
RNPS1	-5625	-5883	3685	2173	1138
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
SMG1	-2541	-1365	1838	6991	3347
SMG5	-6338	-8564	1537	7295	5964
SMG7	-5648	-5578	5198	1498	-49
UBA52	-513	-1242	1530	5448	5828
UPF1	-2339	26	478	3538	3027
UPF2	-4419	-6130	3206	2503	1382
UPF3A	-4731	-2250	5839	2172	4276

---

---

Nonsense-Mediated Decay (NMD)

Nonsense-Mediated Decay (NMD)

metric	value
setSize	81
pMANOVA	0.000117
p.adjustMANOVA	0.00617
s.dist	0.304
s.psf	0.0975
s.psb	-0.0563
s.hcy	0.149
s.folate	0.202
s.vitb12	0.13
p.psf	0.13
p.psb	0.382
p.hcy	0.021
p.folate	0.0017
p.vitb12	0.0442

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	hcy
RPL4	8137	3711
RPL41	7287	4115
RPL3	7916	3364
RPL29	5290	4990
EIF4A3	5779	4502
PABPC1	5582	4238
RPS10	5908	3900
RPS29	5166	4263
RPS27L	4151	5057
RPL23	6505	3169
NCBP1	8402	2448
RPL31	3555	5771
NCBP2	6756	2973
RPS28	8167	2374
RPS3	8185	2229
RPS6	8168	2203
RPS3A	4514	3771
RPL37	6405	2639
RPL32	6861	2458
RPL11	4330	3810

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
CASC3	-5894	-3543	-120	2750	7789
DCP1A	-4668	-4529	1204	4837	3403
EIF4A3	-1889	-241	4502	5779	4014
EIF4G1	-2868	-940	4004	1882	-227
ETF1	-5256	-1911	4663	-25	4397
FAU	-7265	-3975	4740	233	1443
GSPT1	-2286	-956	-604	2009	-353
NCBP1	-2607	-1945	2448	8402	8509
NCBP2	-3917	-5147	2973	6756	7623
PABPC1	-3400	-5506	4238	5582	1293
PNRC2	-4158	-6285	2483	96	54
PPP2CA	-4081	-3471	4425	2847	2701
PPP2R2A	-144	-5849	1125	5472	6709
RNPS1	-5625	-5883	3685	2173	1138
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
SMG1	-2541	-1365	1838	6991	3347
SMG5	-6338	-8564	1537	7295	5964
SMG7	-5648	-5578	5198	1498	-49
UBA52	-513	-1242	1530	5448	5828
UPF1	-2339	26	478	3538	3027
UPF2	-4419	-6130	3206	2503	1382
UPF3A	-4731	-2250	5839	2172	4276

---

---

G2/M Transition

G2/M Transition

metric	value
setSize	143
pMANOVA	0.000122
p.adjustMANOVA	0.00617
s.dist	0.24
s.psf	-0.0502
s.psb	-0.117
s.hcy	0.144
s.folate	0.113
s.vitb12	0.0886
p.psf	0.302
p.psb	0.0159
p.hcy	0.00305
p.folate	0.0197
p.vitb12	0.0686

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	hcy	psb
PSME4	5997	-8991
HMMR	5977	-8925
SKP1	6201	-7721
ACTR1A	6228	-7285
TUBGCP3	6638	-6714
CENPJ	5613	-7834
PSMA1	5104	-8604
PPP1R12A	6142	-6921
RBX1	5617	-7492
CEP76	6523	-6415
CKAP5	4720	-8730
CCNH	5835	-6984
TUBGCP6	6580	-6185
PSMC5	5418	-7267
CEP78	5013	-7490
PSMD3	5506	-6416
MNAT1	5844	-5911
PSMB9	4898	-7032
PSMC6	4301	-7964
CEP250	4881	-6903

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
ACTR1A	-7409	-7285	6228	2166	2934
AKAP9	-879	-2573	3852	3811	6300
ALMS1	-1678	-5983	-1625	6835	3815
AURKA	-4625	-2521	4365	5906	2377
BTRC	-2985	-8093	-1346	7288	8214
CCNA2	-6844	-7471	3487	2247	4856
CCNB1	-8633	-4816	6272	-1067	-816
CCNB2	-6798	-5895	4682	7856	8479
CCNH	-5123	-6984	5835	888	1368
CDC25A	-253	-3390	-1059	8103	6963
CDC25B	-6824	-2908	4768	445	-398
CDC25C	-4167	-6539	3835	6618	5507
CDK1	-3517	-5019	2450	2546	7363
CDK11A	339	-5328	-2613	-215	7932
CDK11B	-7533	-225	3493	1392	1684
CDK2	-3067	-9380	1071	8170	2476
CDK5RAP2	28	-3076	-2525	8391	8566
CDK7	-1359	-7416	1957	8195	7509
CDKN1A	-1859	-8647	-682	379	-950
CENPF	552	-58	5351	4636	6138
CENPJ	-6986	-7834	5613	6967	4084
CEP135	-2407	-7278	2548	5696	6485
CEP152	-5236	-2244	1653	2324	1765
CEP164	-629	-2996	713	7069	7016
CEP192	-7456	-8329	2199	4990	2630
CEP250	-8527	-6903	4881	512	1570
CEP63	-6556	-7691	4259	2923	2119
CEP70	-8174	-6676	3663	2986	1045
CEP76	-8869	-6415	6523	-621	-937
CEP78	-4928	-7490	5013	2801	-327
CKAP5	-4894	-8730	4720	1363	835
CLASP1	-5095	-5549	1549	5253	6532
CSNK1D	-973	-7670	2239	1107	4901
CSNK1E	614	-3165	-729	7983	8577
CUL1	697	205	-2993	1565	8112
DCTN2	-3373	-6548	-2552	7412	7292
DCTN3	-8835	-5606	5566	4936	7213
DYNC1H1	-4365	-3256	5029	425	786
DYNC1I2	-6567	-7070	2439	2184	2874
DYNLL1	-6435	-1692	4607	677	956
EP300	-1930	-7100	4582	8147	5387
FBXL18	-2508	-6650	1835	-840	92
FKBPL	-2321	-3229	39	5493	3759
FOXM1	-7948	-468	1373	1945	2399
GTSE1	-7032	-3414	4753	3073	3539
HAUS1	-8924	-8346	-139	-894	3039
HAUS2	-4906	-6282	1391	4934	5752
HAUS4	-2796	-8059	1165	7833	8154
HAUS5	-8	-7132	-1633	7311	8354
HAUS6	-1545	-9508	2952	8197	8029
HAUS8	-2937	180	4673	-1340	158
HMMR	-8878	-8925	5977	-469	1458
HSP90AA1	-1474	-2948	4393	938	5308
HSP90AB1	-6037	-9040	-1669	7956	8086
LCMT1	-2343	-1444	1427	7665	7357
LIN37	-6842	-8305	2309	5813	1485
LIN52	-4276	-6308	-467	8342	8531
LIN54	-3712	-3019	3438	4972	5802
LIN9	-9052	-1862	6417	-397	-673
MAPRE1	-6287	-7647	-1239	6750	6392
MNAT1	-192	-5911	5844	7743	7276
MYBL2	104	-3426	6528	7182	6078
NDE1	-7104	-8550	191	5467	7621
NEDD1	-3862	-288	6562	-1432	-923
NEK2	-5853	-6431	2954	4274	552
NME7	-5566	-6971	2648	6559	7203
ODF2	-7755	-1603	5376	-1003	-707
OPTN	-8104	-6454	5114	1035	130
PAFAH1B1	-5211	-2836	5904	687	-129
PCM1	-1756	-7343	4253	6955	7282
PCNT	-1548	-9147	-1852	7093	4977
PHLDA1	-7579	-7562	-2341	5921	4423
PKMYT1	-4169	-2770	-825	4841	2226
PLK1	-4551	-1935	-118	2868	3399
PLK4	-1681	-3910	1944	5138	4393
PPME1	-6569	-2868	2989	5385	4482
PPP1CB	-3739	154	-558	4935	2792
PPP1R12A	-8727	-6921	6142	1501	5136
PPP1R12B	-7166	-3002	3352	499	-331
PPP2CA	-4081	-3471	4425	2847	2701
PPP2CB	-1353	77	5390	-624	-872
PPP2R1B	-1840	-3560	3568	7877	5301
PPP2R2A	-144	-5849	1125	5472	6709
PRKACA	-4718	-4025	-1287	480	3795
PSMA1	-8359	-8604	5104	1855	4650
PSMA2	-7938	-2161	5110	1432	8018
PSMA3	-2004	-4530	4184	8188	7955
PSMA5	-3753	-5163	4135	7049	6792
PSMA6	-5756	-9052	230	3273	5895
PSMA7	-5963	-1772	3526	2927	3736
PSMB1	-2258	-1758	1218	4974	2620
PSMB10	-1663	-6710	-165	6829	6594
PSMB3	-3839	-6905	4780	5497	4412
PSMB5	-89	-6668	-1101	7598	7952
PSMB6	-6634	-5888	2326	6558	5006
PSMB7	-5105	-6476	-481	6667	7933
PSMB8	-7792	-3686	5160	756	1587
PSMB9	-8032	-7032	4898	3199	1447
PSMC1	89	-6196	611	7227	6270
PSMC3	-4234	-5168	-1757	3247	5525
PSMC4	-5962	-6708	1563	2130	2138
PSMC5	-7766	-7267	5418	2470	428
PSMC6	-7087	-7964	4301	5996	2878
PSMD1	-1790	-8089	458	4661	6182
PSMD11	-1272	-2207	4285	6544	4390
PSMD12	-2535	-3717	20	7015	7973
PSMD13	-8546	-5774	4927	2662	-882
PSMD14	-2548	-5579	3518	3709	4574
PSMD2	-7305	-6402	3485	3621	4835
PSMD3	-6151	-6416	5506	2545	2496
PSMD4	-7964	-5567	754	5325	7149
PSMD6	-4518	-717	1908	2403	114
PSMD7	-3120	-8646	2963	5075	5520
PSMD8	-4369	-5263	1397	3011	5309
PSMD9	-1075	-5374	3215	4605	1840
PSME1	-4828	-2498	2379	209	820
PSME2	-3988	-5227	2344	6844	5159
PSME3	-502	-1677	210	3994	6092
PSME4	-4990	-8991	5997	207	-839
PSMF1	-490	-5529	-2618	4670	8624
RAB8A	-1364	-5944	2929	5198	5223
RBBP4	-1926	-4404	290	4089	6722
RBX1	-8553	-7492	5617	651	240
RPS27A	-6317	-9335	373	8228	8264
SDCCAG8	-4645	-2484	4907	4864	2284
SKP1	-1797	-7721	6201	2774	2018
TP53	-3124	-9254	3539	7152	6754
TPX2	-3260	-8888	313	8220	8229
TUBA1A	-3868	-6814	281	7982	5851
TUBA4A	-2725	-3627	757	7569	1248
TUBB	-6989	-2735	6157	-695	73
TUBG2	-6985	-7753	1108	3397	4830
TUBGCP2	-8572	-9202	3059	-1079	125
TUBGCP3	-8505	-6714	6638	-52	4915
TUBGCP5	399	79	-2707	8176	1722
TUBGCP6	-8332	-6185	6580	-1186	-842
UBA52	-513	-1242	1530	5448	5828
UBB	-6553	-5964	-13	7418	8036
UBC	-8288	-7011	-1067	5810	7639
WEE1	-6170	-447	3951	633	2639
XPO1	-6677	-4338	4933	4303	2828
YWHAE	138	-1017	-2211	1240	4019
YWHAG	-2464	-4668	3556	3296	1364

---

---

Eukaryotic Translation Elongation

Eukaryotic Translation Elongation

metric	value
setSize	67
pMANOVA	0.000127
p.adjustMANOVA	0.00617
s.dist	0.353
s.psf	0.117
s.psb	-0.0903
s.hcy	0.13
s.folate	0.225
s.vitb12	0.187
p.psf	0.0986
p.psb	0.202
p.hcy	0.067
p.folate	0.00146
p.vitb12	0.00814

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
RPS27A	8228	8264
RPS24	7985	8504
RPSA	8071	8168
RPL15	7772	8423
RPL34	7954	8213
RPS25	8288	7689
RPL28	7634	8337
RPL9	7462	8503
RPS28	8167	7739
RPL41	7287	7829
RPS6	8168	6880
RPL32	6861	8038
RPL37A	6591	8046
RPS16	6351	8153
EEF1B2	6724	7419
RPL23	6505	7202
RPS23	6550	6652
RPL26L1	7153	5923
RPS29	5166	7494
EEF2	5988	6454

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
EEF1A1	-3918	-942	2202	3605	6293
EEF1B2	-4047	-3617	1755	6724	7419
EEF1D	-190	-2379	3533	959	1093
EEF1G	-5422	-4594	3051	186	2016
EEF2	-875	-295	765	5988	6454
FAU	-7265	-3975	4740	233	1443
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
UBA52	-513	-1242	1530	5448	5828

---

---

GTP hydrolysis and joining of the 60S ribosomal subunit

GTP hydrolysis and joining of the 60S ribosomal subunit

metric	value
setSize	83
pMANOVA	0.000136
p.adjustMANOVA	0.00617
s.dist	0.327
s.psf	0.0863
s.psb	-0.0973
s.hcy	0.106
s.folate	0.211
s.vitb12	0.185
p.psf	0.175
p.psb	0.126
p.hcy	0.0955
p.folate	0.000939
p.vitb12	0.00366

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
EIF4H	8386	8557
RPS27A	8228	8264
RPS24	7985	8504
EIF3K	7962	8324
RPSA	8071	8168
RPL15	7772	8423
RPL34	7954	8213
RPS25	8288	7689
RPL28	7634	8337
RPL9	7462	8503
RPS28	8167	7739
RPL41	7287	7829
RPS6	8168	6880
EIF4A2	8016	6992
RPL32	6861	8038
RPL37A	6591	8046
EIF3E	6310	8402
RPS16	6351	8153
EIF2S1	6910	7442
RPL23	6505	7202

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
EIF2S1	-2735	-7410	-1488	6910	7442
EIF2S2	-8040	-2246	4352	4264	1966
EIF3A	-5961	-4394	2363	6467	6750
EIF3B	-7286	-5509	2356	6240	3808
EIF3E	-3852	-2014	1456	6310	8402
EIF3F	-8363	-6470	1695	4913	-256
EIF3G	-1270	-2190	3770	-171	649
EIF3H	-6307	-8861	5530	5136	7922
EIF3I	-1089	-1018	1281	-201	4343
EIF3J	-7128	-8079	1970	1279	1543
EIF3K	-2128	-8866	1472	7962	8324
EIF3L	-5319	-3996	-475	880	7020
EIF3M	-1877	-438	965	-129	2575
EIF4A1	-1333	-1250	3847	5915	4073
EIF4A2	-2633	-5470	2412	8016	6992
EIF4B	-7712	-3860	3758	2671	3062
EIF4E	-2494	-478	798	-590	2108
EIF4G1	-2868	-940	4004	1882	-227
EIF4H	418	-9576	-3055	8386	8557
EIF5	-1766	-4636	1739	2798	3414
EIF5B	-5056	-8930	2159	5991	7633
FAU	-7265	-3975	4740	233	1443
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
UBA52	-513	-1242	1530	5448	5828

---

---

mRNA Splicing

mRNA Splicing

metric	value
setSize	137
pMANOVA	0.000137
p.adjustMANOVA	0.00617
s.dist	0.218
s.psf	-0.127
s.psb	-0.00454
s.hcy	0.109
s.folate	0.133
s.vitb12	0.041
p.psf	0.0106
p.psb	0.927
p.hcy	0.0282
p.folate	0.00735
p.vitb12	0.409

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	psf
PPIL6	7640	-9118
DNAJC8	7931	-7353
U2AF1L4	6821	-8452
RNU12	8329	-6802
SNW1	7224	-7556
POLR2K	7535	-6692
HNRNPC	7786	-6417
PPIL3	6931	-6835
HNRNPK	5391	-8708
DDX42	7469	-6054
SYF2	6860	-6245
CRNKL1	4891	-8653
SNRNP27	4890	-8613
ISY1	5327	-7742
SYMPK	4534	-8912
SNRPG	4428	-8824
PRPF3	8106	-4650
LSM6	6797	-5542
CLP1	4503	-8309
PABPN1	6672	-5567

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
AQR	-6333	-3041	3130	2428	213
BUD31	-5822	-1257	5663	1158	-128
CASC3	-5894	-3543	-120	2750	7789
CCAR1	-6114	-4153	4117	2954	1555
CD2BP2	-7752	-6379	-565	2299	225
CDC40	-5069	-5170	6113	7236	7911
CDC5L	-3718	-8684	2708	4035	466
CHERP	-1036	-1544	150	7588	7250
CLP1	-8309	-8541	3767	4503	5311
CPSF1	-7857	-2180	1761	-275	3766
CPSF2	-8923	-7853	5634	4004	1174
CPSF3	-9106	-320	3820	-995	-1008
CPSF4	-2416	-2946	3597	65	1707
CRNKL1	-8653	-1313	6082	4891	-53
CSTF1	-8368	-1269	6211	3962	-798
CTNNBL1	-260	-2124	-1675	5289	7206
CWC15	-5234	-9143	500	5096	5887
CWC22	-2356	-1364	-624	8283	8440
DDX23	-5303	-5813	1255	6302	2957
DDX42	-6054	-3242	-750	7469	7080
DDX46	-3736	-5546	1628	489	170
DDX5	-8798	-1962	5815	765	8110
DHX16	-6357	-5208	3655	2330	1654
DHX9	-2881	-5212	3182	2843	5648
DNAJC8	-7353	-9020	341	7931	8344
EFTUD2	-6446	-4389	556	371	6704
EIF4A3	-1889	-241	4502	5779	4014
FIP1L1	-3659	-5017	3181	598	4518
FUS	-8674	-8601	5569	646	297
GTF2F1	-6478	-3375	-601	1836	7032
GTF2F2	-4911	-5801	2754	5927	6569
HNRNPA0	-3798	-5600	3243	1046	969
HNRNPA2B1	-5709	-2656	1320	2348	6171
HNRNPC	-6417	-4531	-444	7786	5488
HNRNPD	-4568	-1459	4662	3947	2001
HNRNPF	-4034	-5253	2984	1175	1921
HNRNPH1	-5132	-5113	6459	7063	112
HNRNPK	-8708	-3748	2280	5391	2404
HNRNPL	-2126	-3202	1676	2831	630
HNRNPM	-2262	-6986	-2261	3606	6840
HNRNPR	-8622	-2736	6282	-218	176
HNRNPU	-3813	-1254	860	5008	5617
HNRNPUL1	-3147	-3194	4088	5579	5341
ISY1	-7742	-8825	5271	5327	3431
LSM2	-2021	-1145	-593	6198	4951
LSM3	-2989	-3969	-1227	4544	7387
LSM4	-8436	-1999	5635	3901	3659
LSM5	-6751	-6566	2041	3840	3828
LSM6	-5542	-4880	3191	6797	2059
LSM7	-4523	-8629	-859	6494	-776
NCBP1	-2607	-1945	2448	8402	8509
NCBP2	-3917	-5147	2973	6756	7623
NUDT21	-8225	-7782	5559	3640	1124
PABPN1	-5567	-8318	2534	6672	2442
PAPOLA	-8227	-6469	2436	1653	2471
PCBP1	-2567	-3030	182	6928	6076
PCBP2	-4517	-2508	4187	3727	1131
PDCD7	-4272	-3341	3565	6212	3034
PLRG1	-6202	-6583	4035	1766	5014
POLR2A	-8657	-6301	3361	1117	-706
POLR2B	-2551	-7510	1297	5291	7059
POLR2C	-375	-2722	2661	3775	1272
POLR2D	-4623	-6633	1251	-240	862
POLR2E	-7280	-5905	1641	2768	1465
POLR2F	-2647	22	2490	337	2732
POLR2G	-3892	-6713	3633	6708	4000
POLR2H	-3216	-2022	5045	1005	994
POLR2I	-6360	-3343	1067	691	4207
POLR2K	-6692	-9353	-599	7535	6282
PPIE	-3912	-9284	-319	4108	2543
PPIH	-7408	-5442	4546	4252	3083
PPIL1	-4920	-7462	3201	5396	1591
PPIL3	-6835	-2869	3210	6931	7856
PPIL4	-2779	-5560	1024	2797	3962
PPIL6	-9118	-7739	6689	7640	2461
PPWD1	-5342	-492	37	143	2520
PRCC	-4588	-8058	417	7046	4634
PRPF19	-4491	-7879	1425	5393	5122
PRPF3	-4650	-4881	-1404	8106	7172
PRPF31	-2670	-8967	-2121	7586	8477
PRPF38A	-2486	-8964	-1546	2573	3523
PRPF6	-1239	-6227	4827	4948	8123
PRPF8	-7782	-8620	4488	1852	1835
PTBP1	-813	-1190	921	4122	2968
PUF60	-1473	-835	2132	-56	3923
RBM17	-6730	-4323	5818	-372	2782
RNPC3	-5347	-4075	893	2772	7405
RNPS1	-5625	-5883	3685	2173	1138
RNU11	-4042	-8053	1371	8142	8094
RNU12	-6802	-790	-300	8329	8148
SART1	-2739	-4566	-653	6130	5049
SF1	-4832	-3244	1384	3310	4619
SF3A1	-6165	-5622	5669	-202	298
SF3A2	-159	-1064	5388	7866	8539
SF3A3	-3923	-5941	2407	2044	2601
SF3B2	-3556	-4464	3956	4587	3040
SF3B3	417	-9037	-2254	4250	5408
SF3B4	-1361	-7842	-2440	6419	7910
SF3B5	-3889	-860	5471	6211	5269
SLU7	-7719	-1038	4816	2793	7622
SMNDC1	-4988	-6052	2616	6156	5660
SNRNP200	-8215	-3814	6366	3481	731
SNRNP25	-6385	-7763	4650	2423	-671
SNRNP27	-8613	-4243	5262	4890	4486
SNRNP35	-7994	-7518	4093	-6	2731
SNRNP40	-791	-3141	694	7841	7635
SNRNP48	-7209	-227	225	3610	3769
SNRNP70	-7130	-7607	3062	5116	6103
SNRPA	-1672	-9302	3379	6333	864
SNRPA1	-2752	-2477	-1814	6325	7076
SNRPB	-6711	-3952	5645	4874	4918
SNRPB2	-1249	-6737	3845	3677	4178
SNRPC	-2341	-4312	-1742	8378	7966
SNRPD1	-341	-2294	5156	1350	2265
SNRPD2	-2587	-8080	5812	7972	203
SNRPD3	428	-1268	4403	8221	6276
SNRPE	-4552	-1609	2801	6300	602
SNRPG	-8824	-8240	2782	4428	6962
SNRPN	602	-4875	-871	8320	8000
SNW1	-7556	-9106	4302	7224	7892
SRRM1	-1123	-3198	143	7240	4545
SRRM2	407	-1575	5878	3259	1253
SRRT	-863	-3259	-122	-999	-607
SYF2	-6245	-7645	917	6860	6924
SYMPK	-8912	-7534	4027	4534	5149
TFIP11	-859	-2343	-1766	7655	5721
TXNL4A	-2472	-359	3705	-98	-667
U2AF1	-6388	-3920	-1258	2776	2028
U2AF1L4	-8452	-3382	6502	6821	2490
U2AF2	-269	-3015	2075	2952	1484
USP39	-4669	-4333	-1921	4527	5860
WBP11	-3724	-8455	4297	6347	7147
WBP4	-7960	-8405	-1098	-845	-1183
WDR33	-4998	-3170	2377	1490	1142
XAB2	-8628	-6086	-396	4099	5265
YBX1	-5841	-1802	2033	2163	6021
ZMAT5	-1025	-629	-2802	-1367	-1219

---

---

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

metric	value
setSize	69
pMANOVA	0.000141
p.adjustMANOVA	0.00617
s.dist	0.341
s.psf	0.114
s.psb	-0.0735
s.hcy	0.136
s.folate	0.23
s.vitb12	0.163
p.psf	0.102
p.psb	0.292
p.hcy	0.052
p.folate	0.000992
p.vitb12	0.0195

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
NCBP1	8402	8509
RPS27A	8228	8264
RPS24	7985	8504
RPSA	8071	8168
RPL15	7772	8423
RPL34	7954	8213
RPS25	8288	7689
RPL28	7634	8337
RPL9	7462	8503
RPS28	8167	7739
RPL41	7287	7829
RPS6	8168	6880
RPL32	6861	8038
RPL37A	6591	8046
RPS16	6351	8153
NCBP2	6756	7623
RPL23	6505	7202
RPS23	6550	6652
RPL26L1	7153	5923
RPS29	5166	7494

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
EIF4G1	-2868	-940	4004	1882	-227
ETF1	-5256	-1911	4663	-25	4397
FAU	-7265	-3975	4740	233	1443
GSPT1	-2286	-956	-604	2009	-353
NCBP1	-2607	-1945	2448	8402	8509
NCBP2	-3917	-5147	2973	6756	7623
PABPC1	-3400	-5506	4238	5582	1293
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
UBA52	-513	-1242	1530	5448	5828
UPF1	-2339	26	478	3538	3027

---

---

Selenoamino acid metabolism

Selenoamino acid metabolism

metric	value
setSize	73
pMANOVA	0.000147
p.adjustMANOVA	0.00621
s.dist	0.35
s.psf	0.11
s.psb	-0.132
s.hcy	0.0934
s.folate	0.217
s.vitb12	0.192
p.psf	0.105
p.psb	0.0509
p.hcy	0.169
p.folate	0.00138
p.vitb12	0.0046

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
RPS27A	8228	8264
RPS24	7985	8504
RPSA	8071	8168
RPL15	7772	8423
RPL34	7954	8213
RPS25	8288	7689
RPL28	7634	8337
RPL9	7462	8503
RPS28	8167	7739
EEFSEC	7576	8082
RPL41	7287	7829
RPS6	8168	6880
RPL32	6861	8038
RPL37A	6591	8046
TXNRD1	6429	8167
RPS16	6351	8153
RPL23	6505	7202
AHCY	7903	5698
RPS23	6550	6652
RPL26L1	7153	5923

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
AHCY	-1642	-7068	-144	7903	5698
AIMP2	-8360	-2771	6569	-1212	-1217
CTH	-5129	-7230	1577	4213	6448
EEF1E1	-5428	-6321	-1312	4897	6951
EEFSEC	-1292	-1338	941	7576	8082
FAU	-7265	-3975	4740	233	1443
GSR	-2205	-172	4383	285	1466
PAPSS1	-5230	-4428	3816	-7	5494
PSTK	-5041	-8997	-2776	3968	4483
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
SCLY	-1700	-7289	1799	3064	766
SEPHS2	-2816	-7771	-1308	4943	6367
TXNRD1	175	-4239	-513	6429	8167
UBA52	-513	-1242	1530	5448	5828

---

---

Mitotic G2-G2/M phases

Mitotic G2-G2/M phases

metric	value
setSize	145
pMANOVA	0.000157
p.adjustMANOVA	0.00638
s.dist	0.236
s.psf	-0.0477
s.psb	-0.11
s.hcy	0.137
s.folate	0.114
s.vitb12	0.0974
p.psf	0.323
p.psb	0.0223
p.hcy	0.00446
p.folate	0.0179
p.vitb12	0.0437

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	hcy	folate
MYBL2	6528	7182
MNAT1	5844	7743
CENPJ	5613	6967
EP300	4582	8147
CCNB2	4682	7856
PSMA3	4184	8188
PCM1	4253	6955
PSMA5	4135	7049
PPP2R1B	3568	7877
PSMD11	4285	6544
DCTN3	5566	4936
PSMB3	4780	5497
PSMC6	4301	5996
AURKA	4365	5906
CDC25C	3835	6618
TP53	3539	7152
CENPF	5351	4636
HAUS6	2952	8197
SDCCAG8	4907	4864
XPO1	4933	4303

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
ACTR1A	-7409	-7285	6228	2166	2934
AKAP9	-879	-2573	3852	3811	6300
ALMS1	-1678	-5983	-1625	6835	3815
AURKA	-4625	-2521	4365	5906	2377
BTRC	-2985	-8093	-1346	7288	8214
CCNA2	-6844	-7471	3487	2247	4856
CCNB1	-8633	-4816	6272	-1067	-816
CCNB2	-6798	-5895	4682	7856	8479
CCNH	-5123	-6984	5835	888	1368
CDC25A	-253	-3390	-1059	8103	6963
CDC25B	-6824	-2908	4768	445	-398
CDC25C	-4167	-6539	3835	6618	5507
CDK1	-3517	-5019	2450	2546	7363
CDK11A	339	-5328	-2613	-215	7932
CDK11B	-7533	-225	3493	1392	1684
CDK2	-3067	-9380	1071	8170	2476
CDK5RAP2	28	-3076	-2525	8391	8566
CDK7	-1359	-7416	1957	8195	7509
CDKN1A	-1859	-8647	-682	379	-950
CENPF	552	-58	5351	4636	6138
CENPJ	-6986	-7834	5613	6967	4084
CEP135	-2407	-7278	2548	5696	6485
CEP152	-5236	-2244	1653	2324	1765
CEP164	-629	-2996	713	7069	7016
CEP192	-7456	-8329	2199	4990	2630
CEP250	-8527	-6903	4881	512	1570
CEP63	-6556	-7691	4259	2923	2119
CEP70	-8174	-6676	3663	2986	1045
CEP76	-8869	-6415	6523	-621	-937
CEP78	-4928	-7490	5013	2801	-327
CKAP5	-4894	-8730	4720	1363	835
CLASP1	-5095	-5549	1549	5253	6532
CSNK1D	-973	-7670	2239	1107	4901
CSNK1E	614	-3165	-729	7983	8577
CUL1	697	205	-2993	1565	8112
DCTN2	-3373	-6548	-2552	7412	7292
DCTN3	-8835	-5606	5566	4936	7213
DYNC1H1	-4365	-3256	5029	425	786
DYNC1I2	-6567	-7070	2439	2184	2874
DYNLL1	-6435	-1692	4607	677	956
E2F1	-4735	-1187	2003	924	6888
E2F3	-2379	-4496	-1726	7813	7614
EP300	-1930	-7100	4582	8147	5387
FBXL18	-2508	-6650	1835	-840	92
FKBPL	-2321	-3229	39	5493	3759
FOXM1	-7948	-468	1373	1945	2399
GTSE1	-7032	-3414	4753	3073	3539
HAUS1	-8924	-8346	-139	-894	3039
HAUS2	-4906	-6282	1391	4934	5752
HAUS4	-2796	-8059	1165	7833	8154
HAUS5	-8	-7132	-1633	7311	8354
HAUS6	-1545	-9508	2952	8197	8029
HAUS8	-2937	180	4673	-1340	158
HMMR	-8878	-8925	5977	-469	1458
HSP90AA1	-1474	-2948	4393	938	5308
HSP90AB1	-6037	-9040	-1669	7956	8086
LCMT1	-2343	-1444	1427	7665	7357
LIN37	-6842	-8305	2309	5813	1485
LIN52	-4276	-6308	-467	8342	8531
LIN54	-3712	-3019	3438	4972	5802
LIN9	-9052	-1862	6417	-397	-673
MAPRE1	-6287	-7647	-1239	6750	6392
MNAT1	-192	-5911	5844	7743	7276
MYBL2	104	-3426	6528	7182	6078
NDE1	-7104	-8550	191	5467	7621
NEDD1	-3862	-288	6562	-1432	-923
NEK2	-5853	-6431	2954	4274	552
NME7	-5566	-6971	2648	6559	7203
ODF2	-7755	-1603	5376	-1003	-707
OPTN	-8104	-6454	5114	1035	130
PAFAH1B1	-5211	-2836	5904	687	-129
PCM1	-1756	-7343	4253	6955	7282
PCNT	-1548	-9147	-1852	7093	4977
PHLDA1	-7579	-7562	-2341	5921	4423
PKMYT1	-4169	-2770	-825	4841	2226
PLK1	-4551	-1935	-118	2868	3399
PLK4	-1681	-3910	1944	5138	4393
PPME1	-6569	-2868	2989	5385	4482
PPP1CB	-3739	154	-558	4935	2792
PPP1R12A	-8727	-6921	6142	1501	5136
PPP1R12B	-7166	-3002	3352	499	-331
PPP2CA	-4081	-3471	4425	2847	2701
PPP2CB	-1353	77	5390	-624	-872
PPP2R1B	-1840	-3560	3568	7877	5301
PPP2R2A	-144	-5849	1125	5472	6709
PRKACA	-4718	-4025	-1287	480	3795
PSMA1	-8359	-8604	5104	1855	4650
PSMA2	-7938	-2161	5110	1432	8018
PSMA3	-2004	-4530	4184	8188	7955
PSMA5	-3753	-5163	4135	7049	6792
PSMA6	-5756	-9052	230	3273	5895
PSMA7	-5963	-1772	3526	2927	3736
PSMB1	-2258	-1758	1218	4974	2620
PSMB10	-1663	-6710	-165	6829	6594
PSMB3	-3839	-6905	4780	5497	4412
PSMB5	-89	-6668	-1101	7598	7952
PSMB6	-6634	-5888	2326	6558	5006
PSMB7	-5105	-6476	-481	6667	7933
PSMB8	-7792	-3686	5160	756	1587
PSMB9	-8032	-7032	4898	3199	1447
PSMC1	89	-6196	611	7227	6270
PSMC3	-4234	-5168	-1757	3247	5525
PSMC4	-5962	-6708	1563	2130	2138
PSMC5	-7766	-7267	5418	2470	428
PSMC6	-7087	-7964	4301	5996	2878
PSMD1	-1790	-8089	458	4661	6182
PSMD11	-1272	-2207	4285	6544	4390
PSMD12	-2535	-3717	20	7015	7973
PSMD13	-8546	-5774	4927	2662	-882
PSMD14	-2548	-5579	3518	3709	4574
PSMD2	-7305	-6402	3485	3621	4835
PSMD3	-6151	-6416	5506	2545	2496
PSMD4	-7964	-5567	754	5325	7149
PSMD6	-4518	-717	1908	2403	114
PSMD7	-3120	-8646	2963	5075	5520
PSMD8	-4369	-5263	1397	3011	5309
PSMD9	-1075	-5374	3215	4605	1840
PSME1	-4828	-2498	2379	209	820
PSME2	-3988	-5227	2344	6844	5159
PSME3	-502	-1677	210	3994	6092
PSME4	-4990	-8991	5997	207	-839
PSMF1	-490	-5529	-2618	4670	8624
RAB8A	-1364	-5944	2929	5198	5223
RBBP4	-1926	-4404	290	4089	6722
RBX1	-8553	-7492	5617	651	240
RPS27A	-6317	-9335	373	8228	8264
SDCCAG8	-4645	-2484	4907	4864	2284
SKP1	-1797	-7721	6201	2774	2018
TP53	-3124	-9254	3539	7152	6754
TPX2	-3260	-8888	313	8220	8229
TUBA1A	-3868	-6814	281	7982	5851
TUBA4A	-2725	-3627	757	7569	1248
TUBB	-6989	-2735	6157	-695	73
TUBG2	-6985	-7753	1108	3397	4830
TUBGCP2	-8572	-9202	3059	-1079	125
TUBGCP3	-8505	-6714	6638	-52	4915
TUBGCP5	399	79	-2707	8176	1722
TUBGCP6	-8332	-6185	6580	-1186	-842
UBA52	-513	-1242	1530	5448	5828
UBB	-6553	-5964	-13	7418	8036
UBC	-8288	-7011	-1067	5810	7639
WEE1	-6170	-447	3951	633	2639
XPO1	-6677	-4338	4933	4303	2828
YWHAE	138	-1017	-2211	1240	4019
YWHAG	-2464	-4668	3556	3296	1364

---

---

L13a-mediated translational silencing of Ceruloplasmin expression

L13a-mediated translational silencing of Ceruloplasmin expression

metric	value
setSize	82
pMANOVA	0.000166
p.adjustMANOVA	0.00638
s.dist	0.322
s.psf	0.0854
s.psb	-0.0901
s.hcy	0.113
s.folate	0.214
s.vitb12	0.172
p.psf	0.182
p.psb	0.159
p.hcy	0.0782
p.folate	0.000839
p.vitb12	0.0072

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
EIF4H	8386	8557
RPS27A	8228	8264
RPS24	7985	8504
EIF3K	7962	8324
RPSA	8071	8168
RPL15	7772	8423
RPL34	7954	8213
RPS25	8288	7689
RPL28	7634	8337
RPL9	7462	8503
RPS28	8167	7739
RPL41	7287	7829
RPS6	8168	6880
EIF4A2	8016	6992
RPL32	6861	8038
RPL37A	6591	8046
EIF3E	6310	8402
RPS16	6351	8153
EIF2S1	6910	7442
RPL23	6505	7202

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
EIF2S1	-2735	-7410	-1488	6910	7442
EIF2S2	-8040	-2246	4352	4264	1966
EIF3A	-5961	-4394	2363	6467	6750
EIF3B	-7286	-5509	2356	6240	3808
EIF3E	-3852	-2014	1456	6310	8402
EIF3F	-8363	-6470	1695	4913	-256
EIF3G	-1270	-2190	3770	-171	649
EIF3H	-6307	-8861	5530	5136	7922
EIF3I	-1089	-1018	1281	-201	4343
EIF3J	-7128	-8079	1970	1279	1543
EIF3K	-2128	-8866	1472	7962	8324
EIF3L	-5319	-3996	-475	880	7020
EIF3M	-1877	-438	965	-129	2575
EIF4A1	-1333	-1250	3847	5915	4073
EIF4A2	-2633	-5470	2412	8016	6992
EIF4B	-7712	-3860	3758	2671	3062
EIF4E	-2494	-478	798	-590	2108
EIF4G1	-2868	-940	4004	1882	-227
EIF4H	418	-9576	-3055	8386	8557
FAU	-7265	-3975	4740	233	1443
PABPC1	-3400	-5506	4238	5582	1293
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
UBA52	-513	-1242	1530	5448	5828

---

---

Viral mRNA Translation

Viral mRNA Translation

metric	value
setSize	65
pMANOVA	0.000169
p.adjustMANOVA	0.00638
s.dist	0.343
s.psf	0.109
s.psb	-0.106
s.hcy	0.144
s.folate	0.216
s.vitb12	0.165
p.psf	0.129
p.psb	0.139
p.hcy	0.0454
p.folate	0.0027
p.vitb12	0.0218

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
RPS27A	8228	8264
RPS24	7985	8504
RPSA	8071	8168
RPL15	7772	8423
RPL34	7954	8213
RPS25	8288	7689
RPL28	7634	8337
RPL9	7462	8503
RPS28	8167	7739
RPL41	7287	7829
RPS6	8168	6880
RPL32	6861	8038
RPL37A	6591	8046
RPS16	6351	8153
RPL23	6505	7202
RPS23	6550	6652
RPL26L1	7153	5923
RPS29	5166	7494
RPL22	5041	7376
RPL38	7481	4924

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
DNAJC3	-1761	-825	4154	1358	845
FAU	-7265	-3975	4740	233	1443
GRSF1	-3983	-1055	5934	1119	2634
NA	-3922	-4807	823	2726	3404
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
UBA52	-513	-1242	1530	5448	5828

---

---

Post NMDA receptor activation events

Post NMDA receptor activation events

metric	value
setSize	37
pMANOVA	0.000173
p.adjustMANOVA	0.00638
s.dist	0.475
s.psf	0.153
s.psb	0.221
s.hcy	-0.251
s.folate	-0.234
s.vitb12	-0.188
p.psf	0.108
p.psb	0.0202
p.hcy	0.00821
p.folate	0.0139
p.vitb12	0.0478

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	hcy	folate
RPS6KA1	-2723	-627
GRIN2C	-2408	-394
SRC	-427	-41

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
ARHGEF7	-2889	-963	1038	6761	5725
CALM1	-1140	-3090	-703	2569	5919
CAMK1	622	-1001	-2658	4883	-605
CAMK2D	-7602	-2920	6135	-628	-174
CAMK2G	-250	-62	-829	6968	1605
CAMK4	-258	-3558	2726	1835	284
CAMKK1	-5757	-5738	4543	-336	2542
CAMKK2	-3279	-6235	-2051	293	4332
CREB1	-4159	-1226	472	-273	3361
DLG1	-385	-1091	2874	5485	1201
DLG4	-1757	-7935	-1172	5776	4723
GIT1	443	-5279	-3090	718	4910
GRIN1	244	71	-2485	1161	-555
GRIN2C	-810	-8353	-2408	-394	3376
GRIN2D	-1104	-8108	-2134	1042	7433
HRAS	348	-304	-2761	2241	5443
KPNA2	-7476	-5242	4362	3922	198
KRAS	-3001	-89	138	-784	-790
MAPK1	-2717	-2873	-1146	3217	-292
MAPK3	-6889	-9407	-1492	8081	6172
MAPT	-2959	-1119	201	2894	5154
NRGN	-6866	-2345	776	6581	2683
PDPK1	-6239	-376	3800	444	2190
PRKAA1	-4171	-954	-1152	5406	5062
PRKAB1	-6437	-4951	5662	-167	1351
PRKAB2	-3725	-7118	1621	5427	2154
PRKACA	-4718	-4025	-1287	480	3795
PRKACB	-6646	-908	2348	1167	1023
PRKAG1	-6626	-8822	4778	-622	4636
PRKAG2	-4216	-7353	4444	8	3106
PRKAR1A	-7139	-2501	4900	-147	424
PRKAR1B	-265	-107	-3015	7076	7451
PRKAR2A	-825	-2422	-2557	771	3315
RAC1	-2096	-4182	1706	2583	1143
RPS6KA1	-5437	-3891	-2723	-627	1954
RPS6KA2	-5884	-402	3112	3010	3312
SRC	-5098	-8229	-427	-41	-814

---

---

mRNA Splicing - Major Pathway

mRNA Splicing - Major Pathway

metric	value
setSize	129
pMANOVA	0.000215
p.adjustMANOVA	0.00768
s.dist	0.223
s.psf	-0.119
s.psb	-0.0129
s.hcy	0.12
s.folate	0.138
s.vitb12	0.0409
p.psf	0.0196
p.psb	0.801
p.hcy	0.0188
p.folate	0.00705
p.vitb12	0.425

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	hcy
PPIL6	7640	6689
SNRPD2	7972	5812
HNRNPH1	7063	6459
U2AF1L4	6821	6502
CDC40	7236	6113
SF3A2	7866	5388
SNRPD3	8221	4403
SF3B5	6211	5471
SNW1	7224	4302
CRNKL1	4891	6082
ISY1	5327	5271
SNRPB	4874	5645
WBP11	6347	4297
EIF4A3	5779	4502
SNRNP27	4890	5262
CSTF1	3962	6211
POLR2G	6708	3633
PRPF6	4948	4827
HNRNPUL1	5579	4088
CPSF2	4004	5634

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
AQR	-6333	-3041	3130	2428	213
BUD31	-5822	-1257	5663	1158	-128
CASC3	-5894	-3543	-120	2750	7789
CCAR1	-6114	-4153	4117	2954	1555
CD2BP2	-7752	-6379	-565	2299	225
CDC40	-5069	-5170	6113	7236	7911
CDC5L	-3718	-8684	2708	4035	466
CHERP	-1036	-1544	150	7588	7250
CLP1	-8309	-8541	3767	4503	5311
CPSF1	-7857	-2180	1761	-275	3766
CPSF2	-8923	-7853	5634	4004	1174
CPSF3	-9106	-320	3820	-995	-1008
CPSF4	-2416	-2946	3597	65	1707
CRNKL1	-8653	-1313	6082	4891	-53
CSTF1	-8368	-1269	6211	3962	-798
CTNNBL1	-260	-2124	-1675	5289	7206
CWC15	-5234	-9143	500	5096	5887
CWC22	-2356	-1364	-624	8283	8440
DDX23	-5303	-5813	1255	6302	2957
DDX42	-6054	-3242	-750	7469	7080
DDX46	-3736	-5546	1628	489	170
DDX5	-8798	-1962	5815	765	8110
DHX16	-6357	-5208	3655	2330	1654
DHX9	-2881	-5212	3182	2843	5648
DNAJC8	-7353	-9020	341	7931	8344
EFTUD2	-6446	-4389	556	371	6704
EIF4A3	-1889	-241	4502	5779	4014
FIP1L1	-3659	-5017	3181	598	4518
FUS	-8674	-8601	5569	646	297
GTF2F1	-6478	-3375	-601	1836	7032
GTF2F2	-4911	-5801	2754	5927	6569
HNRNPA0	-3798	-5600	3243	1046	969
HNRNPA2B1	-5709	-2656	1320	2348	6171
HNRNPC	-6417	-4531	-444	7786	5488
HNRNPD	-4568	-1459	4662	3947	2001
HNRNPF	-4034	-5253	2984	1175	1921
HNRNPH1	-5132	-5113	6459	7063	112
HNRNPK	-8708	-3748	2280	5391	2404
HNRNPL	-2126	-3202	1676	2831	630
HNRNPM	-2262	-6986	-2261	3606	6840
HNRNPR	-8622	-2736	6282	-218	176
HNRNPU	-3813	-1254	860	5008	5617
HNRNPUL1	-3147	-3194	4088	5579	5341
ISY1	-7742	-8825	5271	5327	3431
LSM2	-2021	-1145	-593	6198	4951
LSM3	-2989	-3969	-1227	4544	7387
LSM4	-8436	-1999	5635	3901	3659
LSM5	-6751	-6566	2041	3840	3828
LSM6	-5542	-4880	3191	6797	2059
LSM7	-4523	-8629	-859	6494	-776
NCBP1	-2607	-1945	2448	8402	8509
NCBP2	-3917	-5147	2973	6756	7623
NUDT21	-8225	-7782	5559	3640	1124
PABPN1	-5567	-8318	2534	6672	2442
PAPOLA	-8227	-6469	2436	1653	2471
PCBP1	-2567	-3030	182	6928	6076
PCBP2	-4517	-2508	4187	3727	1131
PLRG1	-6202	-6583	4035	1766	5014
POLR2A	-8657	-6301	3361	1117	-706
POLR2B	-2551	-7510	1297	5291	7059
POLR2C	-375	-2722	2661	3775	1272
POLR2D	-4623	-6633	1251	-240	862
POLR2E	-7280	-5905	1641	2768	1465
POLR2F	-2647	22	2490	337	2732
POLR2G	-3892	-6713	3633	6708	4000
POLR2H	-3216	-2022	5045	1005	994
POLR2I	-6360	-3343	1067	691	4207
POLR2K	-6692	-9353	-599	7535	6282
PPIE	-3912	-9284	-319	4108	2543
PPIH	-7408	-5442	4546	4252	3083
PPIL1	-4920	-7462	3201	5396	1591
PPIL3	-6835	-2869	3210	6931	7856
PPIL4	-2779	-5560	1024	2797	3962
PPIL6	-9118	-7739	6689	7640	2461
PPWD1	-5342	-492	37	143	2520
PRCC	-4588	-8058	417	7046	4634
PRPF19	-4491	-7879	1425	5393	5122
PRPF3	-4650	-4881	-1404	8106	7172
PRPF31	-2670	-8967	-2121	7586	8477
PRPF38A	-2486	-8964	-1546	2573	3523
PRPF6	-1239	-6227	4827	4948	8123
PRPF8	-7782	-8620	4488	1852	1835
PTBP1	-813	-1190	921	4122	2968
PUF60	-1473	-835	2132	-56	3923
RBM17	-6730	-4323	5818	-372	2782
RNPS1	-5625	-5883	3685	2173	1138
SART1	-2739	-4566	-653	6130	5049
SF1	-4832	-3244	1384	3310	4619
SF3A1	-6165	-5622	5669	-202	298
SF3A2	-159	-1064	5388	7866	8539
SF3A3	-3923	-5941	2407	2044	2601
SF3B2	-3556	-4464	3956	4587	3040
SF3B3	417	-9037	-2254	4250	5408
SF3B4	-1361	-7842	-2440	6419	7910
SF3B5	-3889	-860	5471	6211	5269
SLU7	-7719	-1038	4816	2793	7622
SMNDC1	-4988	-6052	2616	6156	5660
SNRNP200	-8215	-3814	6366	3481	731
SNRNP27	-8613	-4243	5262	4890	4486
SNRNP40	-791	-3141	694	7841	7635
SNRNP70	-7130	-7607	3062	5116	6103
SNRPA	-1672	-9302	3379	6333	864
SNRPA1	-2752	-2477	-1814	6325	7076
SNRPB	-6711	-3952	5645	4874	4918
SNRPB2	-1249	-6737	3845	3677	4178
SNRPC	-2341	-4312	-1742	8378	7966
SNRPD1	-341	-2294	5156	1350	2265
SNRPD2	-2587	-8080	5812	7972	203
SNRPD3	428	-1268	4403	8221	6276
SNRPE	-4552	-1609	2801	6300	602
SNRPG	-8824	-8240	2782	4428	6962
SNRPN	602	-4875	-871	8320	8000
SNW1	-7556	-9106	4302	7224	7892
SRRM1	-1123	-3198	143	7240	4545
SRRM2	407	-1575	5878	3259	1253
SRRT	-863	-3259	-122	-999	-607
SYF2	-6245	-7645	917	6860	6924
SYMPK	-8912	-7534	4027	4534	5149
TFIP11	-859	-2343	-1766	7655	5721
TXNL4A	-2472	-359	3705	-98	-667
U2AF1	-6388	-3920	-1258	2776	2028
U2AF1L4	-8452	-3382	6502	6821	2490
U2AF2	-269	-3015	2075	2952	1484
USP39	-4669	-4333	-1921	4527	5860
WBP11	-3724	-8455	4297	6347	7147
WBP4	-7960	-8405	-1098	-845	-1183
WDR33	-4998	-3170	2377	1490	1142
XAB2	-8628	-6086	-396	4099	5265
YBX1	-5841	-1802	2033	2163	6021

---

---

SRP-dependent cotranslational protein targeting to membrane

SRP-dependent cotranslational protein targeting to membrane

metric	value
setSize	81
pMANOVA	0.000234
p.adjustMANOVA	0.00788
s.dist	0.314
s.psf	0.0316
s.psb	-0.14
s.hcy	0.123
s.folate	0.21
s.vitb12	0.138
p.psf	0.624
p.psb	0.0301
p.hcy	0.0563
p.folate	0.00113
p.vitb12	0.0318

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	psb
RPS27A	8228	-9335
RPS6	8168	-9376
RPS28	8167	-9366
RPS24	7985	-9105
RPSA	8071	-8950
RPL15	7772	-8740
RPL28	7634	-8709
RPL9	7462	-8612
RPS23	6550	-9223
RPL37A	6591	-9008
RPL23	6505	-8875
RPL41	7287	-7390
SRP72	5621	-8342
SRP19	5734	-7901
RPL29	5290	-8348
SEC11A	5992	-7162
SPCS3	5750	-7437
SSR2	8207	-5033
RPS25	8288	-4836
RPL36	4617	-8044

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
FAU	-7265	-3975	4740	233	1443
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPN1	-5829	-6529	4758	2203	1809
RPN2	-7930	-2850	-773	5499	3675
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
SEC11A	-5755	-7162	2830	5992	4108
SEC11C	-3733	-8634	5529	2181	-737
SEC61A1	-7089	-490	3623	663	-772
SEC61A2	-738	-3246	-2097	5197	4400
SEC61G	-6334	-3621	1774	4736	5281
SPCS2	-5763	-3911	321	4754	4075
SPCS3	-7739	-7437	4489	5750	2469
SRP14	-1346	-3506	652	7728	7410
SRP19	-268	-7901	3247	5734	5955
SRP54	-7158	-6849	1166	5353	4587
SRP68	-7538	-5835	6216	1381	-242
SRP72	-4076	-8342	1611	5621	6027
SRPRB	-2995	-6434	2948	3037	5236
SSR1	-3286	-1615	1511	-313	4618
SSR2	-4122	-5033	-1575	8207	8103
SSR3	-8775	-4685	3472	2528	2715
TRAM1	-8485	-9025	3237	-687	-300
UBA52	-513	-1242	1530	5448	5828

---

---

Formation of a pool of free 40S subunits

Formation of a pool of free 40S subunits

metric	value
setSize	73
pMANOVA	0.000235
p.adjustMANOVA	0.00788
s.dist	0.335
s.psf	0.0766
s.psb	-0.116
s.hcy	0.12
s.folate	0.208
s.vitb12	0.188
p.psf	0.259
p.psb	0.0866
p.hcy	0.078
p.folate	0.00221
p.vitb12	0.00566

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
RPS27A	8228	8264
RPS24	7985	8504
EIF3K	7962	8324
RPSA	8071	8168
RPL15	7772	8423
RPL34	7954	8213
RPS25	8288	7689
RPL28	7634	8337
RPL9	7462	8503
RPS28	8167	7739
RPL41	7287	7829
RPS6	8168	6880
RPL32	6861	8038
RPL37A	6591	8046
EIF3E	6310	8402
RPS16	6351	8153
RPL23	6505	7202
EIF3A	6467	6750
RPS23	6550	6652
RPL26L1	7153	5923

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
EIF3A	-5961	-4394	2363	6467	6750
EIF3B	-7286	-5509	2356	6240	3808
EIF3E	-3852	-2014	1456	6310	8402
EIF3F	-8363	-6470	1695	4913	-256
EIF3G	-1270	-2190	3770	-171	649
EIF3H	-6307	-8861	5530	5136	7922
EIF3I	-1089	-1018	1281	-201	4343
EIF3J	-7128	-8079	1970	1279	1543
EIF3K	-2128	-8866	1472	7962	8324
EIF3L	-5319	-3996	-475	880	7020
EIF3M	-1877	-438	965	-129	2575
FAU	-7265	-3975	4740	233	1443
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
UBA52	-513	-1242	1530	5448	5828

---

---

PKA-mediated phosphorylation of CREB

PKA-mediated phosphorylation of CREB

metric	value
setSize	11
pMANOVA	0.000288
p.adjustMANOVA	0.00939
s.dist	0.793
s.psf	0.00732
s.psb	0.448
s.hcy	-0.444
s.folate	-0.429
s.vitb12	-0.217
p.psf	0.966
p.psb	0.0102
p.hcy	0.0108
p.folate	0.0138
p.vitb12	0.213

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	psb	hcy

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
ADCY4	-4326	-2533	-1935	377	-183
ADCY7	-8384	-9239	-2990	-609	4432
ADCY9	-8670	-84	2546	2727	-326
CALM1	-1140	-3090	-703	2569	5919
CREB1	-4159	-1226	472	-273	3361
NBEA	601	-1104	-1866	1043	-263
PRKACA	-4718	-4025	-1287	480	3795
PRKACB	-6646	-908	2348	1167	1023
PRKAR1A	-7139	-2501	4900	-147	424
PRKAR1B	-265	-107	-3015	7076	7451
PRKAR2A	-825	-2422	-2557	771	3315

---

---

Cap-dependent Translation Initiation

Cap-dependent Translation Initiation

metric	value
setSize	90
pMANOVA	0.000412
p.adjustMANOVA	0.0127
s.dist	0.278
s.psf	0.0643
s.psb	-0.0712
s.hcy	0.134
s.folate	0.174
s.vitb12	0.14
p.psf	0.293
p.psb	0.244
p.hcy	0.0283
p.folate	0.0044
p.vitb12	0.0218

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
EIF4H	8386	8557
RPS27A	8228	8264
RPS24	7985	8504
EIF3K	7962	8324
RPSA	8071	8168
RPL15	7772	8423
RPL34	7954	8213
RPS25	8288	7689
RPL28	7634	8337
RPL9	7462	8503
RPS28	8167	7739
RPL41	7287	7829
RPS6	8168	6880
EIF4A2	8016	6992
RPL32	6861	8038
RPL37A	6591	8046
EIF3E	6310	8402
RPS16	6351	8153
EIF2S1	6910	7442
RPL23	6505	7202

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
EIF2B1	-5980	-1983	6306	353	-282
EIF2B2	-7978	-5656	5499	753	1735
EIF2B3	-2568	-538	-2206	1983	1527
EIF2B4	-7743	-3682	5026	180	663
EIF2B5	-7103	-6653	5033	770	3160
EIF2S1	-2735	-7410	-1488	6910	7442
EIF2S2	-8040	-2246	4352	4264	1966
EIF3A	-5961	-4394	2363	6467	6750
EIF3B	-7286	-5509	2356	6240	3808
EIF3E	-3852	-2014	1456	6310	8402
EIF3F	-8363	-6470	1695	4913	-256
EIF3G	-1270	-2190	3770	-171	649
EIF3H	-6307	-8861	5530	5136	7922
EIF3I	-1089	-1018	1281	-201	4343
EIF3J	-7128	-8079	1970	1279	1543
EIF3K	-2128	-8866	1472	7962	8324
EIF3L	-5319	-3996	-475	880	7020
EIF3M	-1877	-438	965	-129	2575
EIF4A1	-1333	-1250	3847	5915	4073
EIF4A2	-2633	-5470	2412	8016	6992
EIF4B	-7712	-3860	3758	2671	3062
EIF4E	-2494	-478	798	-590	2108
EIF4EBP1	-1302	-577	4751	5966	4456
EIF4G1	-2868	-940	4004	1882	-227
EIF4H	418	-9576	-3055	8386	8557
EIF5	-1766	-4636	1739	2798	3414
EIF5B	-5056	-8930	2159	5991	7633
FAU	-7265	-3975	4740	233	1443
PABPC1	-3400	-5506	4238	5582	1293
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
UBA52	-513	-1242	1530	5448	5828

---

---

Eukaryotic Translation Initiation

Eukaryotic Translation Initiation

metric	value
setSize	90
pMANOVA	0.000412
p.adjustMANOVA	0.0127
s.dist	0.278
s.psf	0.0643
s.psb	-0.0712
s.hcy	0.134
s.folate	0.174
s.vitb12	0.14
p.psf	0.293
p.psb	0.244
p.hcy	0.0283
p.folate	0.0044
p.vitb12	0.0218

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
EIF4H	8386	8557
RPS27A	8228	8264
RPS24	7985	8504
EIF3K	7962	8324
RPSA	8071	8168
RPL15	7772	8423
RPL34	7954	8213
RPS25	8288	7689
RPL28	7634	8337
RPL9	7462	8503
RPS28	8167	7739
RPL41	7287	7829
RPS6	8168	6880
EIF4A2	8016	6992
RPL32	6861	8038
RPL37A	6591	8046
EIF3E	6310	8402
RPS16	6351	8153
EIF2S1	6910	7442
RPL23	6505	7202

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
EIF2B1	-5980	-1983	6306	353	-282
EIF2B2	-7978	-5656	5499	753	1735
EIF2B3	-2568	-538	-2206	1983	1527
EIF2B4	-7743	-3682	5026	180	663
EIF2B5	-7103	-6653	5033	770	3160
EIF2S1	-2735	-7410	-1488	6910	7442
EIF2S2	-8040	-2246	4352	4264	1966
EIF3A	-5961	-4394	2363	6467	6750
EIF3B	-7286	-5509	2356	6240	3808
EIF3E	-3852	-2014	1456	6310	8402
EIF3F	-8363	-6470	1695	4913	-256
EIF3G	-1270	-2190	3770	-171	649
EIF3H	-6307	-8861	5530	5136	7922
EIF3I	-1089	-1018	1281	-201	4343
EIF3J	-7128	-8079	1970	1279	1543
EIF3K	-2128	-8866	1472	7962	8324
EIF3L	-5319	-3996	-475	880	7020
EIF3M	-1877	-438	965	-129	2575
EIF4A1	-1333	-1250	3847	5915	4073
EIF4A2	-2633	-5470	2412	8016	6992
EIF4B	-7712	-3860	3758	2671	3062
EIF4E	-2494	-478	798	-590	2108
EIF4EBP1	-1302	-577	4751	5966	4456
EIF4G1	-2868	-940	4004	1882	-227
EIF4H	418	-9576	-3055	8386	8557
EIF5	-1766	-4636	1739	2798	3414
EIF5B	-5056	-8930	2159	5991	7633
FAU	-7265	-3975	4740	233	1443
PABPC1	-3400	-5506	4238	5582	1293
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
UBA52	-513	-1242	1530	5448	5828

---

---

Eukaryotic Translation Termination

Eukaryotic Translation Termination

metric	value
setSize	66
pMANOVA	0.000486
p.adjustMANOVA	0.0146
s.dist	0.335
s.psf	0.0967
s.psb	-0.0848
s.hcy	0.126
s.folate	0.223
s.vitb12	0.173
p.psf	0.175
p.psb	0.234
p.hcy	0.0775
p.folate	0.00179
p.vitb12	0.015

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
RPS27A	8228	8264
RPS24	7985	8504
RPSA	8071	8168
RPL15	7772	8423
RPL34	7954	8213
RPS25	8288	7689
RPL28	7634	8337
RPL9	7462	8503
RPS28	8167	7739
RPL41	7287	7829
RPS6	8168	6880
RPL32	6861	8038
RPL37A	6591	8046
RPS16	6351	8153
RPL23	6505	7202
RPS23	6550	6652
RPL26L1	7153	5923
RPS29	5166	7494
RPL22	5041	7376
RPL38	7481	4924

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
APEH	-3371	-986	1926	6876	3482
ETF1	-5256	-1911	4663	-25	4397
FAU	-7265	-3975	4740	233	1443
GSPT1	-2286	-956	-604	2009	-353
N6AMT1	-6457	-1073	1655	3174	6658
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
UBA52	-513	-1242	1530	5448	5828

---

---

Metabolism of proteins

Metabolism of proteins

metric	value
setSize	1217
pMANOVA	0.000526
p.adjustMANOVA	0.0152
s.dist	0.0798
s.psf	-0.0183
s.psb	-0.0147
s.hcy	0.0382
s.folate	0.0557
s.vitb12	0.0354
p.psf	0.301
p.psb	0.405
p.hcy	0.0307
p.folate	0.00164
p.vitb12	0.0453

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	hcy
FBXO10	8396	6639
RAB26	8119	6594
EPAS1	7989	6349
ST6GALNAC3	7122	6703
FBXL22	7336	6469
CAPZA1	7377	6364
PTP4A2	7520	5641
ST3GAL1	7679	5472
IKBKE	7875	5255
MRPL13	7092	5810
PRKCSH	6384	6429
MRPL20	6209	6475
WDR5	7756	5173
NSMCE2	6766	5833
ST8SIA1	6791	5758
MRPL35	6889	5628
TOPORS	6486	5887
COPS2	5889	6447
EP300	8147	4582
MRPL2	6617	5589

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
AAAS	-4813	-3658	2354	1828	2776
AARS2	-6296	-3899	43	1413	902
ACTB	-6208	-3505	4760	-298	1025
ACTL6A	-8805	-1309	4239	6022	6212
ACTR10	-5379	-2564	5211	4749	1918
ACTR1A	-7409	-7285	6228	2166	2934
ACTR5	-8696	-7780	6486	5044	566
ACTR8	608	-2131	-2869	623	-69
ADAM10	-4702	-5716	4387	5018	6089
ADAMTS10	-5386	-1901	-2935	2015	5077
ADAMTS13	550	-9071	-1594	7608	-507
ADAMTS17	-1476	-6497	-894	4257	2706
ADAMTS6	-5453	-8470	3067	7123	8336
ADAMTSL4	-4185	51	-1351	8344	5735
ADAMTSL5	746	183	-2971	8415	8330
ADD1	-6511	-1476	-945	-818	3540
ADORA2A	-7161	-3817	1219	-1279	165
ADRB2	-2226	-346	5703	5003	4077
ADRM1	-851	-7204	167	5958	4753
AGBL2	-7457	-8302	1286	3110	3983
AGBL3	-6754	-5330	5620	83	-26
AGBL5	-2267	-3559	5206	934	1212
AGTPBP1	-3803	-3274	-2644	1208	8064
AIMP2	-8360	-2771	6569	-1212	-1217
ALG10	-2830	-5935	265	8009	5409
ALG10B	-4214	-2560	2350	7003	7992
ALG11	-5570	-3833	5549	998	-309
ALG12	-8373	-6466	6378	-603	2484
ALG14	-3840	-8661	-651	7794	8281
ALG2	-2611	-1648	-864	653	1902
ALG3	-4919	-8572	871	7243	7287
ALG5	-4025	-7249	3646	5025	5274
ALG6	-2853	-5102	4230	3423	3905
ALG8	-5326	-8779	4422	5420	5132
ALG9	-1890	-9461	1968	7030	7045
AMDHD2	-5327	-3106	-1128	2429	-357
AMFR	17	-3112	-3060	-4	2422
ANK1	-5629	-123	1369	-164	-954
ANKRD28	-5800	-1881	-2389	-1034	290
ANKRD9	-575	-1333	2030	3897	3568
ANO8	-4205	-2369	6037	150	3042
AP3M1	-6666	-6212	6075	945	5931
APC	-3603	-3481	185	3150	6339
APEH	-3371	-986	1926	6876	3482
APH1A	-8237	-7142	717	6905	4763
APH1B	326	-162	-1202	6499	5567
APLP2	-3955	-4992	-87	3335	2146
APOA1	-7646	-7159	1479	2996	26
APOA5	690	-8652	2018	8330	3418
APP	-3538	-2169	-30	-913	742
ARCN1	-5476	-4750	-329	6647	7549
ARF1	-6964	-7705	-2822	1592	-583
ARF3	-1074	-6090	3794	3113	5034
ARF4	-4348	-6561	2190	6399	5279
ARF5	-6996	-8314	-197	-795	737
ARFGAP1	-1376	-1718	4408	1821	1844
ARFGAP3	-38	-1092	-1835	827	1361
ARFGEF2	-8789	-5812	1916	7565	2971
ARL2	-1803	-7414	-573	6638	4503
ARRB1	-3182	-8181	-3110	1072	6768
ARRB2	-5146	-5863	301	5233	4020
ARSA	-5044	-6371	975	264	4217
ARSB	-6352	-2340	-190	66	-318
ARSG	-6335	-1717	5655	-539	-418
ARSK	-4543	-5207	4065	6506	6773
ASB1	-899	-1500	-1106	-90	-904
ASB13	-230	-2806	-2394	5122	4429
ASB2	-2835	-7199	-3002	6004	7867
ASB6	-2485	-1923	-18	2207	6409
ASB7	-1515	-1084	3983	4528	4093
ASB8	-7989	-3882	3309	2006	4301
ASNS	-4354	-555	3289	1003	753
ASXL1	-102	-4961	2111	5772	7226
ASXL2	-1335	-884	-272	4107	1948
ATF3	-1449	-1825	-731	4764	4613
ATF4	-6404	-9161	5649	-136	-472
ATF6	-1288	-2338	1363	7652	8284
ATP6V0D1	-3499	-2151	3369	1750	2485
ATXN3	-5460	-2237	3228	1341	1795
ATXN7	-1650	-4893	2501	-100	-265
AURKA	-4625	-2521	4365	5906	2377
AURKAIP1	-1094	-7949	-826	8219	3144
AURKB	-5215	-5327	5907	4882	2882
AXIN1	-1106	-5199	-2547	1031	7071
AXIN2	-4628	-981	240	4351	6228
B2M	-7539	-5993	3286	2946	3739
B3GALNT2	-3974	-2427	912	2828	3987
B3GNT2	-6531	-1990	1669	5223	7388
B3GNT7	-4871	-8714	-2193	-1074	5768
B3GNT8	-450	-9296	-2885	4577	-11
B3GNTL1	-7261	-7832	5975	979	1162
B4GALT1	-8395	-2040	3483	-310	-376
B4GALT2	629	217	2040	1059	-65
B4GALT3	-182	-4483	-2523	8319	8150
B4GALT4	-6839	-2845	2900	4578	7431
B4GALT5	-4808	-7113	3936	2045	3633
B4GALT6	-4029	-4485	-2964	946	2078
BARD1	-171	-2147	-100	5242	6156
BCL10	-3859	-6280	4113	1198	167
BECN1	-754	-4937	-198	7186	4563
BET1	-7321	-6952	4625	1613	2024
BET1L	-3811	-4271	1086	3326	7064
BIRC2	-7274	-7610	3690	3133	4507
BIRC3	-3830	-5013	1578	7556	8203
BIRC5	-5343	-8595	2843	5224	6417
BLM	-7368	-4528	3040	6231	1776
BMI1	67	-3601	-2400	1115	4852
BRCA1	-8132	-9292	-334	7510	8255
BTBD1	-3091	-500	5401	2076	388
BTBD6	-1786	-9113	-359	-385	-430
BTRC	-2985	-8093	-1346	7288	8214
C19orf10	-7064	-5724	5373	605	1438
C1GALT1	-1783	-1792	397	3253	4174
CALM1	-1140	-3090	-703	2569	5919
CALR	-1690	-3324	898	7605	1925
CALU	-1125	-4119	-277	6040	6938
CAND1	-7059	-7335	4969	5518	4480
CANX	-2019	-6147	-1853	2736	4338
CAPZA1	322	-9142	6364	7377	-943
CAPZA2	-1348	-1720	3606	5221	7185
CAPZB	-107	-904	-1687	5269	2944
CARS2	-8046	-6326	5227	782	83
CASP8AP2	-4729	-6593	4190	5607	6784
CBX4	-1709	-6954	-659	3637	6241
CBX8	-8609	-449	5928	3266	444
CCDC59	-5808	-4682	3780	1142	3671
CCNA2	-6844	-7471	3487	2247	4856
CCNE1	525	-3003	-755	1514	7279
CCNE2	-3810	-2459	4526	-177	568
CCNF	-632	-625	-2430	8116	6330
CCT2	-669	-3308	1476	5740	7755
CCT3	-3649	-6931	2299	7485	6445
CCT5	-5537	-5092	-2409	7893	8568
CCT6A	-3263	-6184	3454	2623	-347
CCT7	-2979	-3551	257	5618	3264
CCT8	-9044	-6112	6126	-229	-697
CD55	-8816	-5501	4376	-891	25
CD59	-4229	-6100	-1570	3647	5032
CDC20	-212	-931	-491	6613	4602
CDC25A	-253	-3390	-1059	8103	6963
CDC34	-6909	-1140	1212	324	5405
CDC73	-1716	-5973	2966	5847	1101
CDCA8	-4157	-4002	538	7190	8272
CDK1	-3517	-5019	2450	2546	7363
CDKN2A	-1603	-4829	-1553	-652	3818
CEBPB	-1913	-3140	3325	2973	4936
CEBPG	-175	-2309	-1289	4256	5740
CHCHD1	-6970	-8890	2528	7269	942
CHD3	-1562	-1347	5715	-547	-869
CHST10	-8903	-506	1941	-1174	-304
CISH	-7515	-887	6227	-670	-811
CKAP4	-9094	-9483	-2767	-1097	3383
CLSPN	-2500	-4167	5062	7142	6396
CMAS	-36	-333	-646	7928	7513
COG1	-14	-4675	1116	6895	7179
COG2	-8507	-1908	-1711	-1196	-764
COG3	-2623	-7283	-1948	8332	7190
COG4	-2335	-7275	390	8293	8364
COG5	-7176	-4235	6334	2210	4652
COG6	-2916	-1749	1715	692	337
COG7	-4966	-5733	1443	3618	2925
COG8	-2617	-1418	1900	-605	2541
COMMD1	-2511	-8736	3100	3763	5295
COMMD10	-4418	-7793	2129	6575	6584
COMMD2	-8129	-3344	5944	887	1118
COMMD4	-676	-1298	-2422	6154	995
COMMD5	-3167	-8072	3672	4165	3214
COMMD6	-1072	-3885	-6	-480	3193
COMMD7	163	-187	2523	601	576
COMMD8	-3645	-3525	2994	1102	2315
COMMD9	-4073	-7602	996	7150	6478
COPA	-4465	-2535	2079	3749	2870
COPB1	-8607	-5335	5676	1981	4788
COPB2	-6275	-6465	5535	4704	2269
COPE	-7575	-9160	1622	5328	7860
COPS2	-8561	-8721	6447	5889	-1223
COPS3	-3895	-2968	1545	3839	4451
COPS4	-6122	-8752	-937	4942	8027
COPS5	-5164	-8369	1213	5444	8166
COPS6	-2915	-5817	-410	7406	6483
COPS7A	-287	-1992	-7	8214	8338
COPS7B	-295	-6656	836	4022	5987
COPS8	-5558	-7516	1282	4835	3489
COPZ1	-4307	-7969	4328	7550	7704
COPZ2	-2515	-8040	-1171	8268	7084
CPM	-963	-8635	-1892	1276	5736
CREB3	-8784	-9543	1066	7936	8318
CREB3L2	-3227	-5750	-2036	6200	6877
CREB3L4	-7637	-3596	-3079	707	95
CREBBP	493	7	-2526	2622	8628
CSF1	-5333	-8467	2222	4391	5035
CSNK1D	-973	-7670	2239	1107	4901
CSNK2A2	-276	-6345	-188	5902	-421
CSNK2B	-8437	-8556	3108	982	975
CTBP1	176	-9458	-1823	5967	6524
CTDSP2	-7493	-6888	-46	1924	2759
CTNNB1	-7204	-4151	-591	6144	557
CTR9	-4443	-6159	4032	4258	7552
CTSA	-4605	-5598	-1969	1365	1486
CTSC	-2263	-5645	-185	4064	3036
CTSZ	-1256	-6140	-3081	4123	6289
CUL1	697	205	-2993	1565	8112
CUL2	-6279	-4347	4648	4094	359
CUL3	-6281	-2196	3475	-1057	1298
CUL4A	-1702	-2307	2317	4568	4864
CUL5	-6648	-2916	420	-154	-439
CUL7	-5278	-4771	-70	3276	522
CUL9	-4284	-8383	-1664	2085	7865
CXXC1	-8357	-1491	4879	234	1648
CYLD	-3314	-7135	4997	5157	2359
DAD1	-2968	-7699	3143	7230	8572
DAG1	-5529	-8643	-1037	1109	-387
DAP3	-6007	-8770	4420	7632	3089
DAXX	-8213	-4941	3610	4825	1780
DCAF10	-6679	-9260	6125	1281	5847
DCAF11	-6209	-5381	2043	2989	943
DCAF13	-5830	-1699	3821	6595	7638
DCAF16	-7770	-8178	6684	2649	5243
DCAF17	-1747	-5583	2758	3277	612
DCAF4	-6276	-7455	1235	2526	6327
DCAF5	-1782	-2374	2551	2830	2622
DCAF6	-8321	-3340	6512	681	-888
DCAF7	-6356	-7349	3220	1629	4265
DCAF8	-7033	-7019	2345	6220	4267
DCP2	-8598	-4221	4207	1533	-563
DCTN2	-3373	-6548	-2552	7412	7292
DCTN3	-8835	-5606	5566	4936	7213
DCTN4	-2893	-8487	312	7432	7459
DCTN5	-7165	-5448	3216	473	-32
DCTN6	-4909	-3795	1667	1332	4296
DCUN1D2	114	164	-602	1728	1800
DCUN1D3	-8304	-1040	2437	3313	3585
DCUN1D4	-2698	-2987	1997	1988	1398
DCUN1D5	-2115	-3230	5145	2876	4196
DDA1	-6603	-8923	3598	6823	1784
DDB2	-749	-3243	2188	5469	3946
DDIT3	-5917	-8203	3407	-459	650
DDX11	-4545	-5474	5911	3830	6009
DDX17	-2712	-2382	1766	4551	7683
DDX5	-8798	-1962	5815	765	8110
DDX58	-3143	-8063	44	8206	8073
DERL1	-7525	-4174	5525	1574	4926
DERL2	-6378	-1078	-2905	8395	8611
DHDDS	-3619	-6824	-1473	2820	5350
DHPS	-6383	-9086	4645	2433	2742
DIS3	-8552	-9237	3964	2928	1121
DNAJB11	-8969	-7147	-1961	4569	5245
DNAJC24	-1218	-4783	3297	6421	8067
DNAJC3	-1761	-825	4154	1358	845
DNMT1	-5928	-4803	5185	107	-549
DNMT3A	-3596	-6744	-1177	-753	5378
DNMT3B	-4458	-399	238	573	-973
DOHH	-6167	-2834	2703	6714	6602
DOLK	-1277	-982	-1518	4385	5406
DOLPP1	-3242	-5094	3509	-713	4169
DPAGT1	-7223	-7396	3167	2834	6038
DPH1	83	-1356	670	3783	3642
DPH2	-7665	-7179	298	5848	6084
DPH3	-1159	69	6185	-148	3641
DPH5	-5053	-9157	5380	6540	5844
DPM1	-703	-7989	-954	7165	8498
DPM2	-5158	-1702	3248	-117	-478
DPM3	-5549	-6831	775	7179	6186
DPP4	-5478	-794	5490	-1134	-1083
DYNC1H1	-4365	-3256	5029	425	786
DYNC1I2	-6567	-7070	2439	2184	2874
DYNC1LI1	-5010	-1342	2070	1660	915
DYNC1LI2	-3958	-1793	-456	881	-232
DYNLL1	-6435	-1692	4607	677	956
DYNLL2	-1210	-5926	4788	4965	6455
EARS2	-4137	-6866	4064	7289	5765
EDEM1	-2822	-7857	2007	5839	6105
EDEM2	-7656	-9038	5003	4185	1426
EEF1A1	-3918	-942	2202	3605	6293
EEF1B2	-4047	-3617	1755	6724	7419
EEF1D	-190	-2379	3533	959	1093
EEF1E1	-5428	-6321	-1312	4897	6951
EEF1G	-5422	-4594	3051	186	2016
EEF2	-875	-295	765	5988	6454
EID3	458	-1644	-2680	8117	4572
EIF2AK3	-6093	-2306	3410	5151	4532
EIF2B1	-5980	-1983	6306	353	-282
EIF2B2	-7978	-5656	5499	753	1735
EIF2B3	-2568	-538	-2206	1983	1527
EIF2B4	-7743	-3682	5026	180	663
EIF2B5	-7103	-6653	5033	770	3160
EIF2S1	-2735	-7410	-1488	6910	7442
EIF2S2	-8040	-2246	4352	4264	1966
EIF3A	-5961	-4394	2363	6467	6750
EIF3B	-7286	-5509	2356	6240	3808
EIF3E	-3852	-2014	1456	6310	8402
EIF3F	-8363	-6470	1695	4913	-256
EIF3G	-1270	-2190	3770	-171	649
EIF3H	-6307	-8861	5530	5136	7922
EIF3I	-1089	-1018	1281	-201	4343
EIF3J	-7128	-8079	1970	1279	1543
EIF3K	-2128	-8866	1472	7962	8324
EIF3L	-5319	-3996	-475	880	7020
EIF3M	-1877	-438	965	-129	2575
EIF4A1	-1333	-1250	3847	5915	4073
EIF4A2	-2633	-5470	2412	8016	6992
EIF4B	-7712	-3860	3758	2671	3062
EIF4E	-2494	-478	798	-590	2108
EIF4EBP1	-1302	-577	4751	5966	4456
EIF4G1	-2868	-940	4004	1882	-227
EIF4H	418	-9576	-3055	8386	8557
EIF5	-1766	-4636	1739	2798	3414
EIF5A	-5927	-2775	1002	5381	5761
EIF5B	-5056	-8930	2159	5991	7633
ENGASE	-1001	-7362	4565	2627	4981
EP300	-1930	-7100	4582	8147	5387
EPAS1	-8483	-5156	6349	7989	4569
ERAL1	-158	-1271	1794	7911	6412
ERCC8	-3805	143	2927	7084	7436
ERN1	-70	-2056	-1110	7387	4377
ETF1	-5256	-1911	4663	-25	4397
ETFB	-3498	-4725	1341	5508	5459
EXOC1	-99	-5294	-622	4786	6858
EXOC2	-5240	-3284	1604	851	1851
EXOC3	145	-4487	-1442	4743	4841
EXOC4	-3330	-8075	-1030	7809	8451
EXOC6	-685	-3245	-1277	-195	6234
EXOC7	-4666	-1762	2706	788	6123
EXOC8	-179	-1884	3115	6808	4227
EXOSC2	-8729	-9244	2530	3525	4504
EXOSC3	-1149	-6526	748	501	4842
EXOSC4	-5949	-971	3231	1277	-86
EXOSC5	-6533	-4703	1943	-485	-100
EXOSC6	-1630	-2864	1276	6042	4034
EXOSC7	-8091	-8183	3484	4662	6982
EXOSC8	-8053	-4017	6064	3443	6272
EXTL1	-7047	-6160	5182	5879	3598
EXTL3	204	-8096	6120	-1237	477
FAM175A	-2695	-1455	3673	1566	6472
FAM175B	-8210	-7639	1120	-89	1033
FARSA	-3291	-5517	-757	3204	958
FARSB	-7498	-6638	275	5363	5685
FAU	-7265	-3975	4740	233	1443
FBXL12	-6991	-581	4494	-820	4379
FBXL14	-3054	-498	5163	4309	-903
FBXL15	-7226	-9111	-268	1371	3504
FBXL16	672	242	-2899	-1395	-324
FBXL18	-2508	-6650	1835	-840	92
FBXL19	-8636	-3707	-2861	1733	-296
FBXL20	-6005	-9313	-749	4930	4021
FBXL22	-1197	-1083	6469	7336	2869
FBXL3	-7789	-1502	5338	5200	1556
FBXL4	-3451	-9055	2638	16	706
FBXL5	677	-372	2716	6097	2331
FBXL8	-630	-4087	736	6009	7824
FBXO10	267	247	6639	8396	6580
FBXO11	-6034	-8588	6618	-1369	1833
FBXO15	558	-2610	-1612	8179	7913
FBXO21	-7846	-6232	5189	4757	957
FBXO22	-1373	-3656	804	1693	5133
FBXO30	-6162	-890	4877	4397	1884
FBXO31	-3746	-3304	3885	1606	2106
FBXO32	-2491	-1139	540	541	7075
FBXO4	-4837	-5547	17	6734	4712
FBXO6	-412	-8870	-1115	2301	1569
FBXO7	-1902	-4034	69	5714	4819
FBXO9	-3856	-6694	4440	2950	2633
FBXW2	-1825	-780	3068	6836	-611
FBXW4	-7307	-1658	5157	3028	-411
FBXW7	-9000	-6908	6497	538	-1175
FBXW8	-649	-4152	600	2448	4290
FEM1A	-2727	-1865	4091	1354	3016
FEM1B	-7987	-7940	516	5957	1444
FKBP14	-3043	-6948	2632	7278	7152
FKBP8	579	-140	-1302	7814	6667
FN3KRP	-2612	-6199	1403	-350	678
FOXK1	-675	-5341	-2713	6010	2459
FOXK2	-2087	-296	-1562	-181	2482
FSTL3	-7492	190	4261	-1308	1209
FUCA1	165	-1579	-2630	1691	64
FUCA2	-7634	-7314	-1943	-1023	90
FURIN	-1007	-9184	-2837	5106	-1067
FUT8	-2575	-3523	2692	6924	3613
GADD45GIP1	199	-2800	-818	7827	6760
GALNT10	-8570	-5686	1524	458	962
GALNT11	-6785	-2684	5578	125	5162
GALNT12	-2666	-145	524	-939	-1134
GALNT2	-1583	-4442	-704	4030	5598
GALNT3	-6665	-1118	1376	1881	1316
GALNT4	-4470	-3710	6520	-348	3953
GALNT6	-692	-6509	-2653	6509	5039
GALNT7	-8913	-2697	5164	1468	-1053
GAN	-6147	-8532	-1181	1614	3729
GANAB	-3643	-4269	1614	4147	4647
GATA3	63	-635	5837	1509	6375
GBA	-4222	-9367	-764	6120	8011
GBF1	-7041	-4426	1617	891	3354
GCNT1	-788	-9512	-837	8279	7154
GFM1	-5651	-8179	5195	1669	-448
GFM2	-8191	-3352	2245	3148	673
GFPT1	-699	-3605	5420	6637	7162
GGA1	-4417	-5996	785	7329	7470
GGA2	-6042	-3456	5600	241	3183
GGA3	-2741	-6453	3671	7146	741
GGCX	-6348	-2813	5188	5491	5833
GLB1	-4131	-8357	2743	5011	4969
GMDS	573	-5421	1370	6627	3327
GMPPA	-2469	-3813	-1902	3411	4702
GMPPB	-4266	-3363	3812	50	954
GNA15	-8503	-9227	-2799	-1343	1230
GNAQ	-8514	-9553	4384	7124	8580
GNB1	-7545	-2084	-2592	-1002	-473
GNB2	-6564	-4671	4217	2806	1836
GNB4	-5727	-7860	355	1400	5628
GNB5	-5029	-2955	2913	6045	4939
GNE	-4781	-7095	-2248	7450	6678
GNG12	-9078	-8896	6415	-1213	6604
GNG2	454	-690	4308	7887	6859
GNG4	682	214	2653	6944	7223
GNG5	-285	-98	3683	7410	108
GNPNAT1	-2980	-703	-2657	3998	3146
GOLGA2	-1576	-9411	1523	8189	7664
GOLGB1	-6552	-5789	-437	5673	4247
GOLM1	-8171	-9321	-2568	-1391	-942
GOSR1	-292	-5386	-2650	7837	8427
GOSR2	-8188	-7998	5730	4508	2825
GPAA1	-2891	-4695	4045	2185	-444
GPS1	-245	-7408	-2393	5336	3493
GSK3A	-8468	-5067	6226	3196	1223
GSPT1	-2286	-956	-604	2009	-353
H2AFX	-2264	-828	-738	1976	3608
HARS2	-8017	-5862	-266	3147	6498
HDAC1	-6904	-1991	2753	283	4684
HDAC2	-1771	-5541	944	2450	7079
HDAC3	-9055	-9330	6558	230	-121
HDAC4	-1010	-6388	-1332	2655	2319
HDAC7	-1520	-5673	1231	1787	1923
HDGF	-5398	-5865	5336	4468	1257
HERPUD1	-5013	-7218	381	2400	4781
HGS	-712	-4897	5344	178	1524
HIF1A	-7062	-4150	5397	-78	1184
HIPK2	-5323	-2324	2438	6378	7604
HLA-A	-5767	-8381	-2118	-419	3068
HLA-B	-4715	-5358	-648	1763	2446
HNRNPC	-6417	-4531	-444	7786	5488
HNRNPK	-8708	-3748	2280	5391	2404
HYOU1	-6318	-2967	3970	-213	533
IARS2	-8319	-7864	-562	-241	2294
ICMT	212	58	-1229	-327	2856
IDE	-6379	-4191	179	2406	3470
IFIH1	-7260	-8497	5861	3193	5986
IGFBP4	-5632	-9420	-1070	-726	2730
IGFBP6	-3	-1593	-3096	1939	2880
IKBKE	585	-2278	5255	7875	6774
INCENP	-4410	-8460	5832	4041	3256
ING2	-3194	-1322	1934	3924	1708
INO80	-5950	-6544	6054	914	1449
INO80B	-2452	-8176	4742	6568	8495
INO80C	235	-3583	2158	7327	8480
INO80D	-7801	-4229	1042	6175	7437
INO80E	-4977	-2438	1850	7232	8267
ITM2B	-4499	-4963	1292	1288	6003
JOSD1	-5102	-6781	826	-630	2139
JOSD2	-5046	-3080	875	2197	6453
KAT2A	-7487	-2632	438	-1233	-239
KAT2B	-1691	-945	2949	3373	921
KBTBD6	-3627	-6979	-1184	2893	3010
KBTBD7	-2326	-6997	3477	3202	4428
KBTBD8	-8534	-6216	5518	4739	4991
KCTD6	554	-7000	-1828	8292	8031
KCTD7	-3634	-1112	4929	2352	1471
KDELR1	-4593	-5979	3629	1157	234
KDELR2	-5766	-2827	2049	6005	6160
KDM1B	-5638	-6859	2965	3553	7001
KEAP1	-1322	-591	-357	3852	6237
KHSRP	-7489	-9255	4404	558	-20
KIF5B	-7077	-5467	5935	758	818
KIN	-7668	-4012	5650	1499	-493
KLHDC3	-1707	-8337	-1549	7482	8217
KLHL11	-2651	-1877	2621	1848	2729
KLHL2	-5930	-3185	3937	625	-39
KLHL20	-8832	-5042	4010	-780	3375
KLHL21	-6218	-2371	3397	3250	392
KLHL22	-1223	-2584	-1558	4365	2441
KLHL25	-5420	-3664	5423	3691	2552
KLHL5	-8036	-3931	5368	-542	-663
KTN1	-1951	-5288	-2360	7351	571
L3MBTL2	-4529	-3989	-367	4660	4610
LAMB2	-4421	-5640	218	-1176	-1146
LARS2	-2934	-6114	1031	1908	6908
LEO1	-8618	-5644	4930	3302	7199
LGALS1	-8131	-8606	4935	3696	4363
LHB	-8532	-4211	4042	-919	3202
LMAN1	488	118	2118	1191	1770
LMAN2	-1317	-5312	-1662	6375	7306
LMAN2L	-1868	-8491	-2727	8410	8555
LMNA	514	-8510	-2632	4679	3620
LONP2	-1870	-4449	3126	6179	6677
LRRC41	-243	-534	-1240	8108	8242
LRRC49	-1117	-7822	274	5790	6130
LTBP1	-3298	-1312	1418	955	2156
LYPD3	-6471	-102	4918	3169	5354
MAN1A1	-5669	-2455	-899	6764	4153
MAN1A2	-6495	-974	1503	3272	2346
MAN1B1	-4134	174	-2337	1347	1371
MAN1C1	-4696	-1661	1003	-1255	-744
MAN2A1	-4105	-2335	5584	1965	4880
MAN2A2	-8153	-9391	4087	624	-632
MANEA	-2676	-1421	4528	-127	4714
MAP3K7	-2530	-1306	-1330	7710	7672
MARS2	-7312	-4538	3873	4188	4087
MAT2B	-1469	-4092	2525	7443	8238
MAVS	166	-1760	-12	5256	6324
MBD1	-6703	-4979	2052	607	2497
MBD6	-4636	-7403	-2712	4492	1693
MBTPS1	-3947	-8673	3609	4763	6074
MCFD2	-6593	-4935	671	7237	5242
MCRS1	-7301	-3662	3078	3761	5333
MDC1	-5699	-4547	4046	3093	3891
MDM2	-7427	-3880	5322	1489	4370
MDM4	-7073	-6259	4702	2640	5555
MEN1	-5865	-5476	1757	4813	3105
METTL10	-6072	-1856	352	201	1952
MFGE8	-733	-571	467	2122	2220
MGAT1	-5170	-5771	3602	941	525
MGAT2	-8099	-9121	4928	5235	-351
MGAT4A	-7814	-1955	4472	4520	2170
MGAT4B	-2397	-9388	-2560	-761	4006
MGAT5	-103	-2189	-200	7209	6540
MIA3	-3665	-5654	4170	5292	3547
MLEC	-2003	-5344	-366	4800	4320
MOGS	-1596	-2569	5254	3672	3423
MPDU1	-5421	-2467	5981	3875	4119
MPI	-5764	-4458	3894	3332	4313
MRPL1	-6746	-1787	4570	7006	6815
MRPL10	-786	-1007	-761	7697	7848
MRPL11	-4880	-5875	3265	147	4182
MRPL12	-1309	-4997	466	5591	6287
MRPL13	-8735	-8223	5810	7092	8224
MRPL14	-667	-1051	-1838	990	-365
MRPL15	-6415	-1389	2980	2411	519
MRPL16	-5061	-8449	-9	-1346	4
MRPL18	-4852	-5844	4786	2600	5318
MRPL19	-37	-2804	-1571	8025	6914
MRPL2	-2035	-1712	5589	6617	7012
MRPL20	-5258	-279	6475	6209	8374
MRPL21	-5905	-7227	5658	-102	82
MRPL22	-5660	-3584	2829	5218	6730
MRPL23	-4356	-332	1211	1446	8300
MRPL24	-6024	-9230	544	5181	7055
MRPL27	-9122	-3983	-2894	7736	5669
MRPL30	-381	-5023	-740	8047	8478
MRPL32	-6875	-6791	5231	4062	897
MRPL33	-5607	-1372	2688	2630	2837
MRPL34	-4430	-3074	3070	3831	204
MRPL35	-7932	-5420	5628	6889	6736
MRPL36	-6712	-3186	4805	-314	6421
MRPL37	515	-8615	-2025	7358	7851
MRPL38	-5298	-5169	4038	-142	2528
MRPL39	-6150	-7950	4675	7494	4407
MRPL4	-3486	-1691	1073	787	4050
MRPL41	-5024	-259	6710	-27	-1111
MRPL42	-650	-2487	-2221	7815	7845
MRPL43	-7340	-9357	6513	-1040	-378
MRPL44	-5863	-4431	2097	4705	6664
MRPL45	710	113	1302	4727	-801
MRPL46	-7835	-8797	805	6439	7263
MRPL47	-1975	-9059	-2399	8226	8513
MRPL48	-237	-6807	2520	5073	3773
MRPL49	-2765	-5731	2364	4037	1481
MRPL50	-9045	-5855	6409	-611	1858
MRPL51	-5932	-5584	-1595	1507	1375
MRPL52	-8042	-7924	1496	5168	4640
MRPL53	-7601	-6156	6462	726	501
MRPL54	-3548	-3233	1499	6395	6013
MRPL55	-178	-5597	-1737	7303	6025
MRPS10	-1327	-8848	-1956	7836	8245
MRPS11	-6223	-7195	-1268	7667	6295
MRPS12	-1412	-5515	4695	5286	5884
MRPS14	-8654	-4048	6551	1431	126
MRPS15	-7406	-3985	2923	2580	-688
MRPS16	-2402	-7485	3746	7028	5072
MRPS17	-208	-747	-2139	5154	5012
MRPS18A	-301	-2716	-1132	3867	7520
MRPS18B	-6513	-464	-2977	4629	4528
MRPS18C	-3578	-7636	5532	3802	-566
MRPS2	-5575	-6964	-195	2764	8381
MRPS21	-6094	-6447	1047	8122	8510
MRPS22	-1363	-2551	5237	2055	5524
MRPS23	-644	-3801	-888	5857	2823
MRPS24	-7840	-8490	6051	-87	1621
MRPS25	-5834	-4571	3358	1033	6685
MRPS26	-3077	-3406	-115	6194	6018
MRPS27	-4557	-6422	-1266	7438	6001
MRPS28	-8155	-8992	-582	4382	5471
MRPS30	-5315	-8450	715	6402	8170
MRPS31	-956	-7595	-931	7966	8023
MRPS33	-2679	-4289	1141	7992	8164
MRPS34	-4617	-2122	705	1675	2244
MRPS35	-5432	-8124	3409	902	2267
MRPS36	-522	-4459	-1285	6353	2121
MRPS5	-3504	-3293	2558	2651	1888
MRPS6	-542	-1071	-1900	774	-219
MRPS7	-6821	-5037	5357	442	-441
MRPS9	-7831	-9081	5813	3510	5237
MSRA	-1874	-31	6667	-1388	-1226
MSRB2	-8942	-4537	508	-1239	-467
MTFMT	-5091	-2495	200	729	3352
MTIF2	-3294	-3135	3229	6816	7375
MTIF3	-7133	-5631	5696	1863	2658
MTRF1L	-7574	-3870	3048	4244	6509
MUC1	-4476	-7495	-1704	3958	3738
MUC12	-5078	-9061	1150	1462	-977
MUC5B	93	10	977	7907	7156
MUL1	-357	-2315	-1978	3297	-315
MYSM1	-1394	-2787	190	440	6534
N6AMT1	-6457	-1073	1655	3174	6658
N6AMT2	-883	-3706	-284	5330	4608
NAE1	-2348	-2682	2998	4830	3408
NAGK	-7908	-4713	4141	1688	1421
NANP	-5306	-5934	2443	4953	1345
NANS	-1855	-7098	6215	-709	2997
NAPA	-4771	-4172	3419	3421	3563
NAPB	-3048	-3758	-1241	7296	6363
NAPG	-7883	-3757	2297	3752	4952
NAPSA	-1824	-2313	608	869	-837
NARS2	-5966	-7828	4574	4161	7611
NCOA2	-2507	-322	4839	-1083	2427
NCOR2	257	-154	-2696	6978	4125
NCSTN	206	-1585	631	8369	6630
NEDD8	-8718	-9235	-1676	7414	4922
NEGR1	-3377	-4644	-1267	464	3234
NEU1	-5825	-6435	3004	6136	5270
NEU3	-2588	-4063	-1493	4353	4035
NEURL2	569	-134	-2895	5639	6144
NFKB2	-3014	-4873	-613	6407	4396
NFKBIA	-6144	-3024	5246	1860	547
NFRKB	-3265	-4700	-1273	92	2995
NFYA	-6847	-5081	4017	6087	7544
NFYB	-5331	-7807	6315	3986	418
NFYC	-3037	-3834	1043	5339	5668
NGLY1	-2664	-8120	-60	6772	4235
NICN1	-1745	-2556	-1629	6189	2229
NLRP3	-3651	-9524	-3052	6264	8225
NOD1	-8306	-1663	1812	-946	1424
NOD2	-168	202	6204	728	-1064
NOP56	-5280	-7733	2511	1724	4467
NOP58	-8048	-1193	4754	1322	6909
NR1H2	-3926	-3248	3498	6646	6539
NR1H3	-8094	-7268	4817	5532	4758
NR1I2	-5388	-7418	-127	-612	5095
NR2C1	-4001	-8840	-934	7617	7579
NR3C1	-5717	-4190	5002	3820	3029
NR3C2	-7773	-7758	6403	1291	-544
NR4A2	-3020	-2956	4372	710	3607
NSMCE1	-4900	-8412	4409	7297	6517
NSMCE2	330	-9600	5833	6766	4094
NSMCE4A	-3008	-7239	4407	1548	1623
NTNG2	-8842	-9442	-25	2737	528
NUB1	-1087	-1227	-1186	7658	7656
NUCB1	-5954	-4121	-2797	7404	5393
NUP107	-2367	-5920	902	8020	7981
NUP133	-2192	-6208	-1034	6710	4350
NUP153	-4611	-8419	2123	1709	5952
NUP155	-938	-2261	778	3101	6606
NUP160	-4062	-2126	-1133	5658	7516
NUP188	-4111	-2994	3510	3714	3909
NUP205	-8245	-8394	4686	6267	6798
NUP210	-8192	-8465	2605	2001	-159
NUP214	-3272	-1704	2474	2228	1116
NUP35	-1551	-7219	-1373	8140	8243
NUP37	-7550	-421	4573	1438	1480
NUP43	-5408	-4131	4558	2582	2522
NUP50	-4714	-688	2999	1921	1935
NUP54	-1931	-4958	3515	3754	3208
NUP62	-1453	-8038	1978	7023	5407
NUP85	-7303	-8224	5526	3668	1520
NUP93	-3267	-3790	-2168	3175	6994
NUP98	-8199	-889	2149	7764	7066
NUS1	-5657	-3644	2103	2435	3
OS9	-7631	-6146	1976	6158	4228
OTUB1	-592	-2238	-1576	3205	6634
OTUD3	106	-6767	1386	755	3920
OTUD7B	-1358	-2691	71	2205	2388
OXA1L	377	-6751	1349	8131	6365
P2RY2	510	-1510	-2938	5020	5082
P4HB	-5071	-606	2641	1394	3861
PABPC1	-3400	-5506	4238	5582	1293
PAF1	-8709	-1149	5976	-823	2101
PARK2	-5996	-117	5459	197	-982
PARK7	-6126	-3317	1216	2738	4865
PARN	-939	-2441	35	7647	7550
PARP1	-3928	-779	81	6292	-89
PARS2	-5615	-572	2564	3144	5711
PCMT1	-1494	-2557	-260	-750	-374
PCNA	-6011	-2914	1160	5682	4824
PDCL	-2219	-8330	5652	6057	8401
PDIA3	-6238	-7767	3007	2361	3908
PDIA5	-1527	-997	-1211	6665	5513
PDIA6	-7505	-2094	971	1124	3297
PEX10	-204	-45	5766	6098	39
PEX12	-7869	-3655	5869	5510	2757
PEX13	-6585	-9279	3506	5476	7173
PEX14	-3540	-1101	4106	5650	5361
PEX5	-2360	-7031	-2392	-190	1018
PFDN1	-1777	-6578	1762	8190	8390
PFDN2	-5981	-9146	2042	5727	2964
PFDN4	-3787	-6939	3755	6587	5715
PFDN5	-2085	-9337	-156	7097	8138
PGAP1	-5681	-3130	1462	2690	3760
PHC1	-7943	-634	-51	-665	1715
PHC2	327	-5626	4838	-1206	268
PHC3	-5127	-3528	2183	3209	5821
PIAS1	-1067	-2815	-2220	7656	8294
PIAS2	-466	-2200	5048	2856	4226
PIAS3	-972	-3292	-2364	7196	7602
PIAS4	-6294	-3353	5457	2516	-643
PIGC	-824	-2628	-305	3951	4777
PIGF	-5294	-8478	4965	4737	798
PIGH	-5286	-4203	1016	548	1740
PIGK	-7220	-989	5688	1435	4352
PIGL	-8492	-8996	3492	4163	2457
PIGM	-809	-9219	2738	5551	6416
PIGN	-5553	-6390	15	3812	4477
PIGO	-7054	-795	-724	-635	3731
PIGP	-5364	-3943	5705	-861	524
PIGQ	-6130	-4432	3934	-359	1639
PIGS	303	-9320	4647	7282	5101
PIGT	-2366	-4773	-90	7952	7404
PIGU	-8432	-4870	2625	2351	1710
PIGV	-2850	-8711	2413	4488	6252
PIGW	-715	-1085	576	7553	3965
PIGX	-3362	-8009	1438	1937	3066
PIGY	-2769	-6449	-349	1155	2416
PLAUR	-3762	-6152	-1249	6192	7024
PML	-7630	-5702	5799	18	-845
PMM1	-6125	-4586	665	2483	2756
PMM2	-8577	-8819	6514	3504	679
PNPLA2	-6796	-3574	-469	-937	6896
POFUT2	-2217	-1158	4724	-330	922
POLB	-6242	-3519	3427	2194	4345
POM121	-6127	-7922	5593	4069	6325
POM121C	-3786	-5219	3938	5072	3069
POMGNT1	-6142	-6901	-1200	1736	2379
POMT1	-968	-4514	1465	7871	8494
POMT2	-5349	-3276	6240	475	924
PPA1	-3321	-1940	4533	745	5386
PPA2	-2118	-7464	4071	4858	4372
PPP2R5B	-4467	-4603	1078	4371	2363
PPP6C	-7439	-2616	5865	2618	-773
PRKCSH	-5743	-3498	6429	6384	-885
PRMT3	-3148	-1070	4982	5299	4398
PSENEN	-4878	-8056	1104	6061	2116
PSMA1	-8359	-8604	5104	1855	4650
PSMA2	-7938	-2161	5110	1432	8018
PSMA3	-2004	-4530	4184	8188	7955
PSMA5	-3753	-5163	4135	7049	6792
PSMA6	-5756	-9052	230	3273	5895
PSMA7	-5963	-1772	3526	2927	3736
PSMB1	-2258	-1758	1218	4974	2620
PSMB10	-1663	-6710	-165	6829	6594
PSMB3	-3839	-6905	4780	5497	4412
PSMB5	-89	-6668	-1101	7598	7952
PSMB6	-6634	-5888	2326	6558	5006
PSMB7	-5105	-6476	-481	6667	7933
PSMB8	-7792	-3686	5160	756	1587
PSMB9	-8032	-7032	4898	3199	1447
PSMC1	89	-6196	611	7227	6270
PSMC3	-4234	-5168	-1757	3247	5525
PSMC4	-5962	-6708	1563	2130	2138
PSMC5	-7766	-7267	5418	2470	428
PSMC6	-7087	-7964	4301	5996	2878
PSMD1	-1790	-8089	458	4661	6182
PSMD11	-1272	-2207	4285	6544	4390
PSMD12	-2535	-3717	20	7015	7973
PSMD13	-8546	-5774	4927	2662	-882
PSMD14	-2548	-5579	3518	3709	4574
PSMD2	-7305	-6402	3485	3621	4835
PSMD3	-6151	-6416	5506	2545	2496
PSMD4	-7964	-5567	754	5325	7149
PSMD6	-4518	-717	1908	2403	114
PSMD7	-3120	-8646	2963	5075	5520
PSMD8	-4369	-5263	1397	3011	5309
PSMD9	-1075	-5374	3215	4605	1840
PSME1	-4828	-2498	2379	209	820
PSME2	-3988	-5227	2344	6844	5159
PSME3	-502	-1677	210	3994	6092
PSME4	-4990	-8991	5997	207	-839
PSMF1	-490	-5529	-2618	4670	8624
PTCD3	-1408	-7358	-670	8109	8022
PTEN	-6630	-6372	3496	3168	3578
PTP4A2	-1624	-3301	5641	7520	367
PTRH2	-7546	-9265	-1940	6268	8235
QSOX1	-87	-1424	1045	3739	4754
RAB10	-7003	-5011	3622	5993	5691
RAB11A	-7190	-2538	3447	6451	3288
RAB11B	-2884	-2264	16	6093	3257
RAB12	-9104	121	2868	-1403	1415
RAB14	-8712	-6038	6011	5652	6829
RAB18	-1498	-2876	897	2711	282
RAB19	-944	-618	-1395	535	593
RAB1A	-6184	-6579	5660	3203	2130
RAB1B	-2863	-5525	2090	5130	4433
RAB22A	-4762	-2268	1843	-973	5528
RAB23	-1497	-6228	-1776	5294	4832
RAB24	-3306	-7157	1173	3015	6235
RAB26	583	172	6594	8119	-1020
RAB27A	-3757	-8372	5398	3531	4171
RAB2A	-7010	-5090	4608	961	2595
RAB2B	-6186	-5595	822	7613	8034
RAB30	-6714	-5531	584	5834	2906
RAB33B	-7912	-8131	3432	4647	6890
RAB34	-8140	-9423	552	5593	7983
RAB35	-8574	-4256	3906	693	1091
RAB37	-4774	-2312	-1952	4580	590
RAB3A	-328	-4284	-2441	7362	8353
RAB3C	-3795	-388	-2768	-1091	665
RAB3D	-2888	-833	-2893	-1211	2632
RAB40B	-8982	-5101	5463	-812	-562
RAB40C	-7236	-3347	1448	1309	1479
RAB43	-4784	-1386	-2032	6406	8461
RAB4A	306	-3723	-2838	1879	7081
RAB4B	-3235	-4761	3386	5923	7514
RAB5A	-8043	-6498	1345	6038	182
RAB5B	-7108	-7517	2269	7306	6428
RAB5C	-7595	-8913	4994	4203	1559
RAB6A	-7940	-2018	5063	-191	4639
RAB7A	680	-231	-809	7839	7391
RAB8A	-1364	-5944	2929	5198	5223
RAB8B	-2680	-7850	511	6965	3688
RABGGTA	-4389	-2318	1142	3617	2278
RABGGTB	-370	28	546	661	5469
RAD18	-1240	-7876	-2429	7607	8417
RAD21	-6823	-6698	-54	7352	7315
RAD23A	-5600	-1411	-1502	1837	394
RAD23B	-332	-4736	4592	6700	5817
RAD52	-7217	-3241	1814	5232	57
RAE1	-8303	-1469	2950	2287	4628
RANBP2	-3530	-4429	-1283	4903	6045
RANGAP1	-1482	-1294	-174	7332	7247
RARA	-3851	-5917	-718	5229	1350
RARS2	-7264	-3466	4709	1340	5450
RBBP5	-4717	-6933	1153	7370	8180
RBX1	-8553	-7492	5617	651	240
RCE1	-6045	-496	2995	-871	321
RCN1	-2482	-8846	1684	-768	4131
RECK	-1964	-6188	-2021	6901	6781
RELA	100	-4011	-1231	7858	5204
RFT1	-6444	-8425	1624	2532	6461
RFWD2	-7675	-1640	6115	2105	1541
RHOA	-8293	-3660	4371	2719	5343
RHOT1	-8889	-7127	4529	1007	-335
RING1	-4180	-1816	1769	4664	3253
RNF103	-348	-2016	4498	2664	4101
RNF135	-7206	-8712	-2391	-1131	3052
RNF139	-3058	-3698	3148	139	2299
RNF146	61	-776	1775	5492	5289
RNF152	-8095	-3520	1029	2153	2211
RNF168	-6893	-8477	5302	1539	3812
RNF181	-6376	-7979	6202	1946	1157
RNF185	-3254	-6575	2141	7441	7182
RNF2	-7298	-8232	5910	-824	7385
RNF20	-2146	-8463	-3033	8258	8253
RNF40	-2591	-2887	4476	1546	792
RNF5	-2787	-9509	-1809	8413	8618
RNF7	-4710	-9280	3420	6930	8059
RORA	-3243	-1036	5488	901	949
RPA1	-4921	-4495	1606	6872	2672
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPN1	-5829	-6529	4758	2203	1809
RPN2	-7930	-2850	-773	5499	3675
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
RRAGA	-7852	-7960	-2144	-558	-524
RTF1	-4524	-3796	3848	3025	2171
RTN4RL2	-1993	-2587	-2576	8202	8126
RUVBL1	-8888	-6605	4056	5146	2676
RWDD3	-85	-3332	-88	358	-77
SAFB	-2242	-6448	5464	4116	187
SAR1B	-3495	-4332	3324	-470	4072
SARS2	-8811	-2530	6154	-606	-572
SATB1	-6176	-395	4396	-300	6248
SATB2	-896	-650	-2891	4366	8313
SCMH1	-6319	-3234	-1156	-1366	532
SEC11A	-5755	-7162	2830	5992	4108
SEC11C	-3733	-8634	5529	2181	-737
SEC13	-8747	-6731	4873	-516	1432
SEC16A	-5784	105	5475	-832	-905
SEC22A	-7058	-5568	1995	3072	4123
SEC22C	-6572	-3555	4199	5644	5727
SEC23A	-6858	-6096	5194	4291	1315
SEC23IP	-8407	-7461	-1218	4118	-483
SEC24A	-1818	-6055	2422	6858	6378
SEC24B	-7486	-8747	2647	-515	1190
SEC24C	-4318	-8538	-725	8313	8299
SEC24D	-4299	-8581	-2554	8256	7902
SEC31A	-5807	-6735	2273	5944	6183
SEC61A1	-7089	-490	3623	663	-772
SEC61A2	-738	-3246	-2097	5197	4400
SEC61G	-6334	-3621	1774	4736	5281
SEH1L	-7723	-5493	4691	844	4470
SEL1L	-6115	-7821	-1714	7981	8335
SENP1	-2187	-5647	1867	7636	7693
SENP2	-3233	-7488	2494	5083	3562
SENP5	-156	-4165	3331	688	5683
SERP1	-7072	-3720	3682	2235	4376
SHC1	-7992	-5400	6208	4678	5680
SHISA5	-8325	-3215	892	7018	-1155
SHPRH	-4910	-6361	3892	4852	4049
SIAH1	-8497	-8765	-2294	643	5654
SIAH2	-6625	-5703	5168	3042	4187
SIN3A	-3756	-6339	592	7416	5305
SKIV2L	-6148	-4626	3233	3863	1325
SKP1	-1797	-7721	6201	2774	2018
SKP2	-1150	-8814	-743	7917	8093
SLC17A5	-4392	-8444	5995	2576	3070
SLC30A5	-8281	-3864	5875	656	3664
SLC30A6	-1153	-8806	-221	6589	7714
SLC30A7	-1452	-5968	4202	7680	6158
SLC35A1	-5065	-7715	1670	5870	6251
SLC35C1	-3545	-3991	-794	2036	3433
SMAD1	-1542	-3232	735	916	4962
SMAD2	-4667	-1340	-1780	1601	3499
SMAD3	-7758	-897	6553	-1022	-659
SMAD7	455	-6703	1274	5703	7089
SMC3	-5441	-8998	4416	6498	3310
SMC5	-6781	-7978	2628	6642	8453
SMC6	-8593	-3255	4769	-549	-368
SMURF2	708	2	-2739	7533	1376
SOCS2	-2662	-5769	2725	2395	6424
SOCS3	341	-708	6669	3230	-1061
SOCS5	-3236	-8857	-255	7803	6410
SORL1	-6616	-4575	-1278	-776	5918
SP100	-2190	-8469	3155	1899	2907
SP3	-5369	-1645	5717	2896	9
SPCS2	-5763	-3911	321	4754	4075
SPCS3	-7739	-7437	4489	5750	2469
SPON2	74	-4095	-2836	6080	-176
SPSB1	-1639	-1886	1558	-1041	2076
SPSB3	-3455	-6941	4183	2162	5304
SPTAN1	-8704	-4943	6573	-1297	-835
SPTBN1	-7444	-5406	2492	2170	5111
SPTBN4	-4072	-1980	914	3252	1938
SPTBN5	-244	-1778	837	6387	6355
SRD5A3	-962	-2081	4168	4277	4730
SRP14	-1346	-3506	652	7728	7410
SRP19	-268	-7901	3247	5734	5955
SRP54	-7158	-6849	1166	5353	4587
SRP68	-7538	-5835	6216	1381	-242
SRP72	-4076	-8342	1611	5621	6027
SRPRB	-2995	-6434	2948	3037	5236
SSR1	-3286	-1615	1511	-313	4618
SSR2	-4122	-5033	-1575	8207	8103
SSR3	-8775	-4685	3472	2528	2715
ST3GAL1	-5368	-3778	5472	7679	4130
ST3GAL2	-7313	-7401	235	2189	740
ST3GAL3	-8906	-4498	5961	4025	2713
ST3GAL4	112	-2799	-1527	4884	8184
ST3GAL5	-3359	-7805	660	5362	7532
ST3GAL6	-2314	-3469	1259	6186	736
ST6GAL1	-1413	-4185	2215	6342	5754
ST6GALNAC3	-143	-64	6703	7122	7430
ST6GALNAC4	-7254	-6819	-193	-511	-624
ST6GALNAC6	-5661	-9168	-341	-557	-541
ST8SIA1	-4734	-2087	5758	6791	-497
ST8SIA4	-5220	-9035	4599	6099	3685
STAG1	-6618	-7770	5829	5087	5078
STAM	-4825	-5121	1679	5826	7984
STAM2	-3617	-2892	1112	3704	4369
STAMBP	-6316	-7911	2671	6783	7626
STAMBPL1	-8083	-4466	5178	1683	704
STAT3	-3331	-987	2282	6265	6816
STT3A	-3616	-6322	4108	7010	6718
STX17	-6211	-9024	28	4235	6949
STX1A	-4435	-985	1081	-249	515
STX5	-3888	-2896	-637	7896	6901
SUDS3	-3253	-8777	4899	1308	4935
SUMF1	-4101	-5265	-1095	4352	5825
SUMF2	-855	-6728	-784	7208	3989
SUMO1	-1344	-2879	-2075	6159	7290
SUMO3	-2609	-3231	-1745	996	85
SYVN1	-5670	-2067	910	6180	3170
TADA2B	-1461	-142	1823	-74	4078
TAF10	-5247	-2585	4705	602	899
TARS2	-1132	-7015	-15	8362	8483
TBC1D20	-6767	-2421	1855	2028	3533
TBCA	-463	-2527	-540	2272	2994
TBCB	-8274	-6031	732	3188	2002
TBCC	-8901	-8386	6217	-839	-341
TBCD	-76	-517	5716	240	313
TBCE	-6535	-4748	1413	5428	7770
TCF7L2	-7405	-2037	3276	2998	5867
TCP1	-8266	-6258	2106	7495	8432
TDG	-288	-7762	-1917	8247	6967
TFAP2A	-3925	-9449	-1913	6218	7511
TFPT	-1058	-7898	-2284	8300	8521
TGFA	-5080	-2472	5807	-671	-627
TGFB1	-7281	-5508	2486	2936	2848
TGFBR1	-2334	-7494	1720	3493	3904
TGFBR2	-4689	-7228	5441	1980	4083
TGOLN2	-8138	-6134	5108	-506	439
THRA	-1371	-8717	2319	5058	2627
TLN1	-7861	-695	3119	3139	4159
TMED10	-7377	-5050	1682	6628	7620
TMED2	-7519	-3354	561	2232	1294
TMED3	-5242	-2625	346	690	2581
TMED7	-8783	-8609	5699	4866	7280
TMED9	-3704	-6297	-663	6625	6891
TMEM115	-8698	-8713	5776	6	861
TMEM129	-5488	-4759	6614	-367	-1082
TNFAIP3	-6612	-7584	5836	1534	1457
TNIP1	-2806	-6959	-218	3567	6543
TNIP2	-7	-2323	-2433	3173	3406
TNKS	-2216	-4124	-22	5455	5217
TNKS2	-4000	-6759	3776	1093	4990
TOMM20	643	146	4679	-1146	-1101
TOP1	-2148	-4574	3950	2149	1728
TOP2A	-5361	-7888	803	8006	6217
TOP2B	-1580	-2672	1910	6999	6960
TOPORS	-4195	-8045	5887	6486	7634
TP53	-3124	-9254	3539	7152	6754
TP53BP1	-3674	-4932	673	6576	6545
TPP1	-5411	-6606	-4	7788	6850
TPR	-1912	-1701	2275	6893	903
TPST1	-1022	-5373	984	7610	6008
TPST2	-1129	-2030	3000	4755	2109
TRAF2	-5646	-753	6129	529	-379
TRAF3	-4118	-875	169	-1272	1532
TRAF6	-7129	-4104	2839	613	2526
TRAM1	-8485	-9025	3237	-687	-300
TRAPPC1	-4436	-4262	-374	2718	1959
TRAPPC10	-5656	-8672	-2704	4360	-1210
TRAPPC2L	-5257	-8451	1242	5169	8106
TRAPPC3	-4811	-2119	-2546	6608	6900
TRAPPC4	-3878	-8781	2979	1216	3255
TRAPPC5	-8295	-5576	-1805	0	908
TRAPPC6A	-9015	-4546	3028	8099	-1036
TRAPPC6B	-5051	-8431	3787	7217	5441
TRAPPC9	-3027	-6909	2175	1529	2529
TRIM13	-8092	-3337	835	3649	4232
TRIM25	-4291	-5485	3781	5282	463
TRIM27	-4472	-2364	4151	2412	349
TRIM28	146	-1261	-318	2832	972
TRRAP	-2257	-7507	278	4585	4771
TSFM	-5316	-7071	2654	6415	6525
TSPAN14	534	-3120	1194	6807	4224
TSPAN33	-4732	-8810	4557	-207	-146
TSPAN5	-471	67	-2656	-1143	-615
TTF1	-822	-226	4471	3679	69
TTL	-3372	-6068	-10	6263	500
TTLL1	32	-4265	-2628	5990	7051
TTLL11	-840	-8085	978	3638	-245
TTLL12	-1142	85	1008	5754	717
TTLL3	-2616	-451	1205	7279	2298
TTLL4	-1590	-2274	349	1902	3213
TTLL5	-8067	-771	4077	3377	-742
TTLL7	4	-4614	-2881	8039	6191
TTLL9	-4425	-462	808	6051	1963
TUBA1A	-3868	-6814	281	7982	5851
TUBA1B	-2586	-3957	1859	3184	4585
TUBA1C	-3611	-1926	3980	5273	1821
TUBA4A	-2725	-3627	757	7569	1248
TUBA4B	-8730	-3132	6556	-578	-182
TUBB2A	-1141	-1970	-2479	3793	3564
TUFM	-1864	-8200	1588	7516	470
TXN	-7099	-7476	1364	7676	6700
UAP1	-6685	-2301	3014	407	4070
UBA2	-3502	-392	553	3787	4097
UBA3	-3474	-745	704	7413	8312
UBA52	-513	-1242	1530	5448	5828
UBA6	-8873	-5736	3437	3482	6094
UBB	-6553	-5964	-13	7418	8036
UBC	-8288	-7011	-1067	5810	7639
UBE2B	-4516	-1947	1366	6358	5610
UBE2C	-759	-2829	-1688	6275	6660
UBE2D1	-2809	-3007	-157	1866	1336
UBE2D2	-6363	-1008	5167	-393	-568
UBE2D3	-4755	-7137	3581	7910	2953
UBE2E1	-4493	-4384	-1323	3040	2903
UBE2E3	-2160	-906	-1348	-1251	-1108
UBE2F	-2235	-1657	6294	-1082	2619
UBE2G1	-4006	-4569	1642	816	3028
UBE2G2	-7651	-5176	3744	994	-339
UBE2H	172	-1860	1339	6629	6855
UBE2I	-3937	-1487	5265	-28	148
UBE2J2	-583	-4774	-1981	4511	6758
UBE2K	-978	-391	4999	1619	1087
UBE2L3	-3559	-1748	-11	2911	2251
UBE2L6	-5254	-6752	603	450	2698
UBE2M	-3069	-1533	3396	-942	4735
UBE2N	-8194	-8856	-1821	-825	-1145
UBE2Q2	-8565	-7200	1458	6490	8370
UBE2R2	-8949	-2851	6510	-759	-1035
UBE2T	-6943	-8057	5392	369	2236
UBE2V2	-7680	-3487	3079	-616	-361
UBE2W	-803	-4327	-855	5897	1255
UBE2Z	-6728	-7851	1890	5388	2527
UBXN1	-2252	-2223	2482	3634	4846
UBXN7	-6374	-7963	6394	401	2860
UCHL3	-664	-7322	-534	4625	3351
UFD1L	-7894	-8244	2539	7708	8017
UGGT1	-5547	-6949	3861	3912	3548
UHRF2	-8619	-7936	1718	5317	-267
ULBP2	-3931	-4469	4255	2803	6662
USO1	-8493	-8242	6098	1982	4249
USP10	-2685	-8258	-1590	-93	1505
USP12	352	-4957	-2187	7104	7047
USP13	-4799	-1221	5232	6389	4082
USP14	-2095	-1317	302	6436	6946
USP15	-5174	-5192	4914	2735	3921
USP16	-8808	-6240	2312	1958	1688
USP18	-200	-7803	113	2125	-739
USP19	-4507	-3381	-1394	5909	1667
USP2	-5986	-5195	1704	2488	4570
USP21	-1479	-3509	-2088	5489	6977
USP22	-2063	-5366	5326	-517	391
USP24	221	-636	3109	-116	461
USP25	-8320	11	6733	-1387	-1202
USP28	-5440	-991	-2373	5267	1646
USP3	-6078	-2823	2554	3925	662
USP30	-4751	-1066	987	6170	403
USP33	-3204	-3393	4583	6511	4700
USP34	-729	-6742	324	1790	-237
USP4	-7252	-4845	2705	1264	1725
USP42	-406	-8	-2238	2654	6671
USP44	331	-326	-2792	3503	3131
USP47	-8922	-8188	3669	6113	7808
USP48	-6003	-5222	4467	3588	4198
USP49	-2526	-7280	-1301	6802	7871
USP5	-2897	-5948	4338	4296	2456
USP7	-785	-3900	-607	3283	3867
USP8	-6864	-8438	-1196	7149	7434
VAMP2	-4164	-4621	543	2158	382
VARS2	-303	-5204	-1138	3461	2611
VCP	-4088	-3661	-905	7139	8260
VCPIP1	-5837	-7616	-1236	5844	7502
VDAC1	-1027	-5688	2143	1034	1304
VDAC3	-4358	-5287	6536	4448	-918
VDR	-7371	-7003	844	3598	4388
VHL	-2603	-4287	1575	4912	6757
WAC	-6775	-1763	2537	-284	-386
WARS2	-4166	-5009	1831	3396	4041
WDR20	-6408	-6946	4847	3900	-384
WDR48	-2800	-2562	-1290	6566	4214
WDR5	-4706	-8796	5173	7756	7244
WDR61	-8482	-7359	5946	2635	-612
WDTC1	-5249	-3468	3888	5276	1697
WFS1	-6748	-838	5871	2665	2694
WIPI1	-1507	-725	253	7161	5009
WRAP53	-7202	-7942	3872	4639	2800
WRN	-7185	-2945	3981	-1274	860
WSB1	-5505	-2271	4486	438	2574
WSB2	-8962	-9478	-2148	-1425	-931
XPC	-3039	-5500	2993	4100	3765
XRCC4	-7386	-8512	5923	5722	6299
XRN2	-1731	-7300	2453	2897	4923
YARS2	-3470	-6904	3065	5089	6838
YIF1A	-4301	-6158	2153	2439	1691
YKT6	-7255	-7292	4242	4541	1502
YOD1	-72	-379	-1159	7307	5503
YY1	-2929	-3640	-1971	4006	2436
ZBTB16	395	88	3616	903	7671
ZBTB17	-3750	-1416	-43	1876	530
ZDHHC2	-8169	-5215	2587	-968	-489
ZNF131	-7092	-4508	4441	2174	1044

---

---

Regulation of TP53 Activity through Methylation

Regulation of TP53 Activity through Methylation

metric	value
setSize	16
pMANOVA	0.000532
p.adjustMANOVA	0.0152
s.dist	0.749
s.psf	-0.255
s.psb	-0.368
s.hcy	-0.0393
s.folate	0.404
s.vitb12	0.443
p.psf	0.0771
p.psb	0.0109
p.hcy	0.786
p.folate	0.00513
p.vitb12	0.00218

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	vitb12	folate
RPS27A	8264	8228
UBB	8036	7418
SMYD2	8295	5869
TP53	6754	7152
UBC	7639	5810
TTC5	6501	6770
EP300	5387	8147
PRMT5	6609	6109
UBA52	5828	5448
ATM	5420	5612
EHMT2	5712	5245
CHEK2	3994	6076
JMY	4425	3757
MDM4	5555	2640
MDM2	4370	1489
EHMT1	1333	2017

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
ATM	-8275	-7820	5395	5612	5420
CHEK2	-7879	-8563	-348	6076	3994
EHMT1	-12	-5791	328	2017	1333
EHMT2	-7541	-7444	3294	5245	5712
EP300	-1930	-7100	4582	8147	5387
JMY	-8788	138	114	3757	4425
MDM2	-7427	-3880	5322	1489	4370
MDM4	-7073	-6259	4702	2640	5555
PRMT5	-4742	-9448	38	6109	6609
RPS27A	-6317	-9335	373	8228	8264
SMYD2	-1041	-7604	-498	5869	8295
TP53	-3124	-9254	3539	7152	6754
TTC5	-7635	-7331	-1297	6770	6501
UBA52	-513	-1242	1530	5448	5828
UBB	-6553	-5964	-13	7418	8036
UBC	-8288	-7011	-1067	5810	7639

---

---

Cellular responses to stress

Cellular responses to stress

metric	value
setSize	425
pMANOVA	0.000549
p.adjustMANOVA	0.0153
s.dist	0.12
s.psf	0.0119
s.psb	0.00575
s.hcy	0.0801
s.folate	0.0782
s.vitb12	0.0402
p.psf	0.677
p.psb	0.841
p.hcy	0.00516
p.folate	0.00631
p.vitb12	0.161

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	hcy	folate
EPAS1	6349	7989
CAPZA1	6364	7377
FOS	6620	6248
EP300	4582	8147
TXNIP	4854	7449
PSMA3	4184	8188
WDR24	6397	4896
RPA3	4462	6870
GSK3B	5172	5856
ATM	5395	5612
RPL4	3711	8137
COX11	4571	6567
RPL41	4115	7287
ATP6V1C1	4518	6598
NUP205	4686	6267
PSMA5	4135	7049
TNRC6B	4883	5846
HMGA1	4669	6077
UBE2D3	3581	7910
ATP6V0E1	5107	5545

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
AAAS	-4813	-3658	2354	1828	2776
ABCC1	-340	-1988	-468	7984	2125
ACD	-4066	-313	3133	-1249	-913
ACTR10	-5379	-2564	5211	4749	1918
ACTR1A	-7409	-7285	6228	2166	2934
AKT1S1	-6014	-4204	4892	4560	3462
ANAPC1	-4888	-4370	4561	5142	1218
ANAPC10	-404	-8610	-361	6447	2473
ANAPC11	-1837	-244	601	4297	4855
ANAPC2	-5187	-4944	5252	-135	-940
ANAPC4	-1773	-8700	4698	4531	5293
ANAPC5	-2266	-8728	1095	6000	7040
ANAPC7	-3940	-8396	2305	7272	5608
APOA1	-7646	-7159	1479	2996	26
ARNT	-1050	-3672	1230	5259	6747
ARNTL	-5169	-1447	413	3086	7286
ASNS	-4354	-555	3289	1003	753
ATF3	-1449	-1825	-731	4764	4613
ATF4	-6404	-9161	5649	-136	-472
ATM	-8275	-7820	5395	5612	5420
ATOX1	-5644	-4346	5890	-297	-240
ATP6V0B	-7452	-1006	4033	214	-858
ATP6V0C	-556	-2680	-2828	3869	1352
ATP6V0D1	-3499	-2151	3369	1750	2485
ATP6V0E1	-5753	-5829	5107	5545	2249
ATP6V0E2	-970	-2187	-2997	4105	7563
ATP6V1A	-8528	-8015	4569	4317	605
ATP6V1B2	-6568	-3841	-1144	1247	3694
ATP6V1C1	-567	-7013	4518	6598	4656
ATP6V1E1	-2421	-6611	613	8262	7479
ATP6V1F	-252	-1893	2531	5882	8175
ATP6V1G2	-9097	-5621	763	7718	8016
ATP6V1H	-1687	-4122	-409	3576	5224
ATR	-7759	-7294	5030	3018	2218
BACH1	549	-1443	-473	-508	5708
BAG2	-5290	-3302	-1616	3589	8013
BAG3	-8136	-5149	3829	856	918
BAG4	-8027	-1984	1154	4204	2366
BAG5	-5195	-515	1250	-1170	1322
BLVRA	-4801	-847	3693	-1190	-965
BLVRB	-8149	-2186	-2908	-1116	-1179
BMI1	67	-3601	-2400	1115	4852
C12orf66	-1680	-1879	13	4843	5180
CABIN1	-6741	-6457	6468	2079	-319
CAMK2D	-7602	-2920	6135	-628	-174
CAMK2G	-250	-62	-829	6968	1605
CAPZA1	322	-9142	6364	7377	-943
CAPZA2	-1348	-1720	3606	5221	7185
CAPZB	-107	-904	-1687	5269	2944
CAT	477	-544	573	2534	6713
CBX4	-1709	-6954	-659	3637	6241
CBX6	-7000	-7981	6483	146	-910
CBX8	-8609	-449	5928	3266	444
CCNA2	-6844	-7471	3487	2247	4856
CCNE1	525	-3003	-755	1514	7279
CCNE2	-3810	-2459	4526	-177	568
CCS	-5288	-9042	-1157	7108	6561
CDC16	-1108	-909	-2388	2815	1317
CDC23	-1180	-4858	84	8244	8117
CDK2	-3067	-9380	1071	8170	2476
CDK4	-5104	-3263	1863	4831	3952
CDK6	-1505	-5601	3867	3476	2214
CDKN1A	-1859	-8647	-682	379	-950
CDKN1B	-6280	-4166	4449	4561	3488
CDKN2A	-1603	-4829	-1553	-652	3818
CDKN2C	-1733	-6562	242	1412	5472
CDKN2D	-3062	-1885	3696	3381	6513
CEBPB	-1913	-3140	3325	2973	4936
CEBPG	-175	-2309	-1289	4256	5740
CHAC1	-7839	-5827	4762	3535	-209
CHD9	-5009	-1522	-612	3889	5338
CITED2	-6940	-7599	5053	1324	3665
CLOCK	-4455	-1545	99	4719	5714
COX11	-5435	-3736	4571	6567	1012
COX16	-5641	-7884	950	7504	6975
COX19	-6020	-6417	369	1393	3300
COX5A	-1730	-4669	-1310	4144	5481
COX5B	-3551	-3965	2006	7151	6865
COX6A1	-867	-7163	1268	6383	4032
COX6B1	-1491	-5188	-732	6962	8216
COX6C	-7936	-8942	3884	-513	2985
COX7A2L	-8868	-3000	1597	2482	7694
COX7C	-5100	-5924	1879	4772	5704
COX8A	-5724	-5857	880	6491	5184
CREB1	-4159	-1226	472	-273	3361
CREBBP	493	7	-2526	2622	8628
CRTC1	-122	-2273	525	2561	1772
CRTC2	-7075	-4865	4099	4404	6868
CRTC3	238	-2	5695	176	2669
CSNK2A2	-276	-6345	-188	5902	-421
CSNK2B	-8437	-8556	3108	982	975
CUL1	697	205	-2993	1565	8112
CUL2	-6279	-4347	4648	4094	359
CUL3	-6281	-2196	3475	-1057	1298
CYBA	-1389	-6143	3156	3491	3666
CYCS	-6191	-2897	1651	2816	5215
DCTN2	-3373	-6548	-2552	7412	7292
DCTN3	-8835	-5606	5566	4936	7213
DCTN4	-2893	-8487	312	7432	7459
DCTN5	-7165	-5448	3216	473	-32
DCTN6	-4909	-3795	1667	1332	4296
DDIT3	-5917	-8203	3407	-459	650
DEDD2	-2701	-3169	3797	4838	3381
DEPDC5	-3444	-7696	-2320	1410	4250
DNAJA1	-93	132	-1827	7499	6261
DNAJA2	275	-2181	1698	6273	-273
DNAJA4	-6232	207	6694	-226	754
DNAJB1	-4227	-6647	377	3390	1990
DNAJB6	-7685	-6871	5304	-735	573
DNAJC2	97	-5426	-358	8135	5980
DYNC1H1	-4365	-3256	5029	425	786
DYNC1I2	-6567	-7070	2439	2184	2874
DYNC1LI1	-5010	-1342	2070	1660	915
DYNC1LI2	-3958	-1793	-456	881	-232
DYNLL1	-6435	-1692	4607	677	956
DYNLL2	-1210	-5926	4788	4965	6455
E2F1	-4735	-1187	2003	924	6888
E2F2	-3044	-4814	3131	3050	3652
E2F3	-2379	-4496	-1726	7813	7614
EED	-8844	-8560	4593	4771	6631
EEF1A1	-3918	-942	2202	3605	6293
EGLN1	-60	-5871	-2124	8223	7944
EGLN2	-2843	-5439	4458	4046	2177
EHMT1	-12	-5791	328	2017	1333
EHMT2	-7541	-7444	3294	5245	5712
EIF2AK1	-7230	-8122	2416	5852	5153
EIF2AK4	-6058	-5930	2320	1957	2309
EIF2S1	-2735	-7410	-1488	6910	7442
EIF2S2	-8040	-2246	4352	4264	1966
EP300	-1930	-7100	4582	8147	5387
EP400	484	-461	4622	5120	2610
EPAS1	-8483	-5156	6349	7989	4569
ERF	-4985	-5458	3608	4005	2664
ETS1	-7449	-7744	5601	1125	2169
ETS2	-4893	-1349	-1495	3857	721
EZH2	-4051	-7225	5422	2942	7416
FAU	-7265	-3975	4740	233	1443
FBXL17	-2337	-5524	3311	6515	1773
FKBP4	-1969	-5456	2181	3069	2487
FKBP5	-3625	-7627	4717	1106	2235
FLCN	-1711	-2578	1818	6363	4260
FNIP1	-5455	-7316	4455	3081	3342
FOS	-8502	-9581	6620	6248	7506
FZR1	-640	-846	4578	-149	3801
GATSL3	-3237	-5756	-1321	7513	4501
GPX1	-3550	-5627	130	4782	1013
GRB10	675	-561	-1415	4276	4197
GSK3B	-1534	-6592	5172	5856	3113
GSR	-2205	-172	4383	285	1466
GSTP1	-326	-691	-2505	712	3156
H2AFX	-2264	-828	-738	1976	3608
HDAC3	-9055	-9330	6558	230	-121
HIF1A	-7062	-4150	5397	-78	1184
HIF1AN	-1301	-1400	1299	5789	841
HIGD1A	-2038	-3440	896	3895	202
HIRA	-1987	-39	1044	360	2884
HM13	-2048	-1966	-2537	800	6306
HMGA1	-7018	-1560	4669	6077	2296
HMOX2	-141	-575	2624	4799	4252
HSBP1	189	-1900	-2748	5163	6151
HSF1	490	-9422	-2169	4986	1489
HSP90AA1	-1474	-2948	4393	938	5308
HSP90AB1	-6037	-9040	-1669	7956	8086
HSPA13	-5580	-8222	4649	5794	7518
HSPA14	82	-8574	-988	5724	8425
HSPA1A	-8087	-7146	832	3274	3761
HSPA1B	-4452	-4831	5474	3271	1652
HSPA1L	-7811	-6206	3350	6071	5134
HSPA2	-8530	-5139	6296	1465	150
HSPA4	-5353	-356	5240	668	1932
HSPA4L	-8085	-2728	-1472	6423	4415
HSPA9	-5213	-1958	1744	1649	1753
HSPH1	-8905	-7450	4860	2620	604
ID1	-2473	-1630	3279	156	588
ITFG2	-7522	-6667	4923	4624	4118
JUN	-6776	-4272	3366	5820	1877
KAT5	-7746	-4286	3717	4016	3371
KDM6B	-8034	-4837	6246	893	386
KEAP1	-1322	-591	-357	3852	6237
KPTN	-4400	-5154	5359	2907	3021
LIMD1	-3141	-6803	1326	102	3655
LMNB1	-7257	-5018	3817	4000	853
LRPPRC	-4961	-2405	1190	3407	7367
MAFK	-714	-1847	-2057	5960	5148
MAP2K3	-577	-6000	-511	7845	6935
MAP2K4	-6526	-3031	4063	74	2710
MAP2K6	-5401	-9451	4916	2846	7797
MAP2K7	-2470	-645	5221	2695	6109
MAP3K5	-4609	-7123	-1855	503	2941
MAP4K4	-203	-3423	4307	1504	4107
MAPK1	-2717	-2873	-1146	3217	-292
MAPK14	-7648	-3775	1942	1668	1054
MAPK3	-6889	-9407	-1492	8081	6172
MAPK7	-4367	-2784	5377	5187	5682
MAPK9	-844	-1217	-75	523	1058
MAPKAPK2	-6467	-6863	2498	2575	888
MAPKAPK3	-8353	-5254	6059	-307	-594
MDM2	-7427	-3880	5322	1489	4370
MDM4	-7073	-6259	4702	2640	5555
MED1	438	-491	-1355	7088	7424
MEF2D	-4997	-1942	-1583	4899	3276
MINK1	-8882	-5766	6097	4429	2824
MIOS	-7928	-7769	6014	3424	1036
MLST8	-8369	-6085	1877	-364	-70
MOV10	462	-4832	-2848	8151	7977
MRPL18	-4852	-5844	4786	2600	5318
MTOR	-1522	-7624	213	6768	6238
NBN	-3696	-7848	771	7212	5058
NCF4	447	-228	-3102	7926	6586
NCOA2	-2507	-322	4839	-1083	2427
NCOA6	-2318	-77	4775	4117	4801
NCOR1	131	-1246	-1234	2574	280
NCOR2	257	-154	-2696	6978	4125
NDUFA4	-6747	-2769	4324	3990	4883
NFE2L2	-3262	-7196	1041	6320	4104
NLRP3	-3651	-9524	-3052	6264	8225
NR1D1	-5550	-5486	2675	2544	116
NR3C1	-5717	-4190	5002	3820	3029
NR3C2	-7773	-7758	6403	1291	-544
NUDT2	-5456	-2020	6336	2955	-1120
NUP107	-2367	-5920	902	8020	7981
NUP133	-2192	-6208	-1034	6710	4350
NUP153	-4611	-8419	2123	1709	5952
NUP155	-938	-2261	778	3101	6606
NUP160	-4062	-2126	-1133	5658	7516
NUP188	-4111	-2994	3510	3714	3909
NUP205	-8245	-8394	4686	6267	6798
NUP210	-8192	-8465	2605	2001	-159
NUP214	-3272	-1704	2474	2228	1116
NUP35	-1551	-7219	-1373	8140	8243
NUP37	-7550	-421	4573	1438	1480
NUP43	-5408	-4131	4558	2582	2522
NUP50	-4714	-688	2999	1921	1935
NUP54	-1931	-4958	3515	3754	3208
NUP62	-1453	-8038	1978	7023	5407
NUP85	-7303	-8224	5526	3668	1520
NUP93	-3267	-3790	-2168	3175	6994
NUP98	-8199	-889	2149	7764	7066
P4HB	-5071	-606	2641	1394	3861
PHC1	-7943	-634	-51	-665	1715
PHC2	327	-5626	4838	-1206	268
PHC3	-5127	-3528	2183	3209	5821
POM121	-6127	-7922	5593	4069	6325
POM121C	-3786	-5219	3938	5072	3069
PPP1R15A	-1922	-1371	-1148	1777	7112
PRDX1	-2592	-6678	2169	7162	7386
PRDX2	-362	-1430	-885	3342	1366
PRDX3	589	-2507	753	8311	6286
PRDX5	-5684	-3972	3801	4783	2005
PRDX6	-1920	-3917	5689	1434	2846
PRKCD	-6607	-1968	5933	-938	2142
PSMA1	-8359	-8604	5104	1855	4650
PSMA2	-7938	-2161	5110	1432	8018
PSMA3	-2004	-4530	4184	8188	7955
PSMA5	-3753	-5163	4135	7049	6792
PSMA6	-5756	-9052	230	3273	5895
PSMA7	-5963	-1772	3526	2927	3736
PSMB1	-2258	-1758	1218	4974	2620
PSMB10	-1663	-6710	-165	6829	6594
PSMB3	-3839	-6905	4780	5497	4412
PSMB5	-89	-6668	-1101	7598	7952
PSMB6	-6634	-5888	2326	6558	5006
PSMB7	-5105	-6476	-481	6667	7933
PSMB8	-7792	-3686	5160	756	1587
PSMB9	-8032	-7032	4898	3199	1447
PSMC1	89	-6196	611	7227	6270
PSMC3	-4234	-5168	-1757	3247	5525
PSMC4	-5962	-6708	1563	2130	2138
PSMC5	-7766	-7267	5418	2470	428
PSMC6	-7087	-7964	4301	5996	2878
PSMD1	-1790	-8089	458	4661	6182
PSMD11	-1272	-2207	4285	6544	4390
PSMD12	-2535	-3717	20	7015	7973
PSMD13	-8546	-5774	4927	2662	-882
PSMD14	-2548	-5579	3518	3709	4574
PSMD2	-7305	-6402	3485	3621	4835
PSMD3	-6151	-6416	5506	2545	2496
PSMD4	-7964	-5567	754	5325	7149
PSMD6	-4518	-717	1908	2403	114
PSMD7	-3120	-8646	2963	5075	5520
PSMD8	-4369	-5263	1397	3011	5309
PSMD9	-1075	-5374	3215	4605	1840
PSME1	-4828	-2498	2379	209	820
PSME2	-3988	-5227	2344	6844	5159
PSME3	-502	-1677	210	3994	6092
PSME4	-4990	-8991	5997	207	-839
PSMF1	-490	-5529	-2618	4670	8624
PTGES3	-2862	-6925	6314	2982	4506
RAD50	-2315	-2352	2399	2091	556
RAE1	-8303	-1469	2950	2287	4628
RAI1	-3134	-4362	-1201	4178	6826
RANBP2	-3530	-4429	-1283	4903	6045
RB1	-3440	-7436	2475	4145	2659
RBBP4	-1926	-4404	290	4089	6722
RBX1	-8553	-7492	5617	651	240
RELA	100	-4011	-1231	7858	5204
RHEB	-8809	-4716	2271	702	-1069
RING1	-4180	-1816	1769	4664	3253
RNF2	-7298	-8232	5910	-824	7385
RORA	-3243	-1036	5488	901	949
RPA1	-4921	-4495	1606	6872	2672
RPA3	-7347	-4983	4462	6870	6874
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS19BP1	-8448	-6834	2764	2023	2015
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS6KA1	-5437	-3891	-2723	-627	1954
RPS6KA2	-5884	-402	3112	3010	3312
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
RPTOR	-710	-706	4723	3819	1986
RRAGA	-7852	-7960	-2144	-558	-524
RRAGC	-1516	-3639	-234	7226	7584
RRAGD	-3672	-1495	-1951	7231	5962
SCMH1	-6319	-3234	-1156	-1366	532
SCO1	-4730	-6138	6503	3255	218
SCO2	-4238	-160	-1569	2147	1139
SEC13	-8747	-6731	4873	-516	1432
SEH1L	-7723	-5493	4691	844	4470
SERPINH1	-3308	-6565	436	5737	3238
SESN1	-7052	-7620	-108	3760	5142
SESN2	-6557	-5030	2854	2636	581
SIN3A	-3756	-6339	592	7416	5305
SIN3B	-5728	-6577	4958	4540	8349
SIRT1	-4482	-5574	-1480	1164	4588
SKP1	-1797	-7721	6201	2774	2018
SKP2	-1150	-8814	-743	7917	8093
SLC38A9	-6647	-7447	5307	-774	509
SOD1	-4942	-4268	580	5875	2227
SOD2	-48	-5922	2479	4301	5703
SP1	-8205	-6021	4034	2297	2451
ST13	-7141	-201	1543	4655	4194
STAT3	-3331	-987	2282	6265	6816
STIP1	-7004	-5727	4236	3689	6906
SURF1	-5536	-1734	5443	2676	-686
TACO1	-8537	-5891	1634	4509	2124
TBL1XR1	-5330	-680	4052	4546	2292
TCIRG1	-3406	-1528	-2103	6845	4525
TERF1	-4657	-5906	936	5088	3646
TERF2	-8117	-8978	1787	2541	1152
TERF2IP	-3819	-8159	5281	1951	676
TFDP1	191	-2894	-2589	638	513
TINF2	-8428	-6625	5012	-23	-8
TNIK	-925	-6245	3505	4614	6196
TNRC6A	-5935	-4254	5456	4870	6042
TNRC6B	-5203	-6029	4883	5846	3955
TP53	-3124	-9254	3539	7152	6754
TPR	-1912	-1701	2275	6893	903
TRIB3	-780	-6700	-1072	2683	5446
TXN	-7099	-7476	1364	7676	6700
TXN2	-5354	-2406	-2050	4994	7435
TXNIP	-7152	-5823	4854	7449	7537
TXNRD1	175	-4239	-513	6429	8167
TXNRD2	-2178	-2021	4773	2434	-765
UBA52	-513	-1242	1530	5448	5828
UBB	-6553	-5964	-13	7418	8036
UBC	-8288	-7011	-1067	5810	7639
UBE2C	-759	-2829	-1688	6275	6660
UBE2D1	-2809	-3007	-157	1866	1336
UBE2D2	-6363	-1008	5167	-393	-568
UBE2D3	-4755	-7137	3581	7910	2953
UBE2E1	-4493	-4384	-1323	3040	2903
UBN1	-354	-1526	1162	7721	4677
VCP	-4088	-3661	-905	7139	8260
VEGFA	-2139	-4266	73	5304	4047
VHL	-2603	-4287	1575	4912	6757
WDR24	-6682	-2454	6397	4896	1607
WDR59	205	-1009	-781	2538	1826
XPO1	-6677	-4338	4933	4303	2828
YWHAE	138	-1017	-2211	1240	4019

---

---

PLC beta mediated events

PLC beta mediated events

metric	value
setSize	29
pMANOVA	0.000589
p.adjustMANOVA	0.016
s.dist	0.527
s.psf	-0.0875
s.psb	0.0587
s.hcy	-0.153
s.folate	-0.389
s.vitb12	-0.303
p.psf	0.415
p.psb	0.584
p.hcy	0.155
p.folate	0.000292
p.vitb12	0.00475

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
PLCB2	-912	-362
CAMK2D	-628	-174

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
ADCY4	-4326	-2533	-1935	377	-183
ADCY7	-8384	-9239	-2990	-609	4432
ADCY9	-8670	-84	2546	2727	-326
AHCYL1	-3448	-6342	5224	266	-471
CALM1	-1140	-3090	-703	2569	5919
CAMK2D	-7602	-2920	6135	-628	-174
CAMK2G	-250	-62	-829	6968	1605
CAMK4	-258	-3558	2726	1835	284
CAMKK1	-5757	-5738	4543	-336	2542
CAMKK2	-3279	-6235	-2051	293	4332
CREB1	-4159	-1226	472	-273	3361
GNA15	-8503	-9227	-2799	-1343	1230
GNAQ	-8514	-9553	4384	7124	8580
ITPR1	-4479	-8421	3245	7110	5588
ITPR2	-5513	-7757	824	190	1738
ITPR3	-5067	-3268	1806	1758	825
KPNA2	-7476	-5242	4362	3922	198
MAPK1	-2717	-2873	-1146	3217	-292
NBEA	601	-1104	-1866	1043	-263
PDE1B	-2193	-8036	-1367	-308	2187
PLCB2	-9002	-6406	1115	-912	-362
PLCB3	-1778	-7628	-1041	-1010	195
PRKACA	-4718	-4025	-1287	480	3795
PRKACB	-6646	-908	2348	1167	1023
PRKAR1A	-7139	-2501	4900	-147	424
PRKAR1B	-265	-107	-3015	7076	7451
PRKAR2A	-825	-2422	-2557	771	3315
PRKCA	-5820	-4955	3971	3486	5016
PRKCD	-6607	-1968	5933	-938	2142

---

---

Response of EIF2AK4 (GCN2) to amino acid deficiency

Response of EIF2AK4 (GCN2) to amino acid deficiency

metric	value
setSize	72
pMANOVA	0.000612
p.adjustMANOVA	0.0162
s.dist	0.31
s.psf	0.102
s.psb	-0.119
s.hcy	0.113
s.folate	0.191
s.vitb12	0.151
p.psf	0.136
p.psb	0.082
p.hcy	0.0973
p.folate	0.00525
p.vitb12	0.0275

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
RPS27A	8228	8264
RPS24	7985	8504
RPSA	8071	8168
RPL15	7772	8423
RPL34	7954	8213
RPS25	8288	7689
RPL28	7634	8337
RPL9	7462	8503
RPS28	8167	7739
RPL41	7287	7829
RPS6	8168	6880
RPL32	6861	8038
RPL37A	6591	8046
RPS16	6351	8153
EIF2S1	6910	7442
RPL23	6505	7202
RPS23	6550	6652
RPL26L1	7153	5923
RPS29	5166	7494
RPL22	5041	7376

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
ASNS	-4354	-555	3289	1003	753
ATF3	-1449	-1825	-731	4764	4613
ATF4	-6404	-9161	5649	-136	-472
CEBPB	-1913	-3140	3325	2973	4936
CEBPG	-175	-2309	-1289	4256	5740
DDIT3	-5917	-8203	3407	-459	650
EIF2AK4	-6058	-5930	2320	1957	2309
EIF2S1	-2735	-7410	-1488	6910	7442
EIF2S2	-8040	-2246	4352	4264	1966
FAU	-7265	-3975	4740	233	1443
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
TRIB3	-780	-6700	-1072	2683	5446
UBA52	-513	-1242	1530	5448	5828

---

---

Separation of Sister Chromatids

Separation of Sister Chromatids

metric	value
setSize	141
pMANOVA	0.00079
p.adjustMANOVA	0.0205
s.dist	0.226
s.psf	-0.0572
s.psb	-0.0692
s.hcy	0.0786
s.folate	0.161
s.vitb12	0.104
p.psf	0.243
p.psb	0.158
p.hcy	0.109
p.folate	0.00101
p.vitb12	0.0332

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
ZWILCH	8324	8308
RPS27A	8228	8264
CDC23	8244	8117
PSMA3	8188	7955
NUP107	8020	7981
SPC25	8021	7791
SKA2	8095	7700
PSMB5	7598	7952
UBB	7418	8036
CDCA8	7190	8272
PSMD12	7015	7973
NUP98	7764	7066
RAD21	7352	7315
RANGAP1	7332	7247
PSMB7	6667	7933
PPP2R5E	6882	7627
PPP2R5D	6390	7682
PSMA5	7049	6792
MAD2L1	6862	6842
PSMC1	7227	6270

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
AHCTF1	-958	-5776	-1162	5566	2735
ANAPC1	-4888	-4370	4561	5142	1218
ANAPC10	-404	-8610	-361	6447	2473
ANAPC11	-1837	-244	601	4297	4855
ANAPC2	-5187	-4944	5252	-135	-940
ANAPC4	-1773	-8700	4698	4531	5293
ANAPC5	-2266	-8728	1095	6000	7040
ANAPC7	-3940	-8396	2305	7272	5608
APITD1	-7436	-4833	3086	-1142	-173
AURKB	-5215	-5327	5907	4882	2882
B9D2	-6812	-1761	3803	2128	3929
BIRC5	-5343	-8595	2843	5224	6417
BUB1	-5409	-7034	-1899	3149	4435
BUB1B	-7490	-8066	1793	6952	3147
BUB3	-1044	-2492	-425	6580	5165
CDC16	-1108	-909	-2388	2815	1317
CDC20	-212	-931	-491	6613	4602
CDC23	-1180	-4858	84	8244	8117
CDCA5	-1121	-417	3175	3307	5915
CDCA8	-4157	-4002	538	7190	8272
CENPA	-5443	-3670	4463	-64	856
CENPE	-2106	-3196	899	5698	6188
CENPF	552	-58	5351	4636	6138
CENPH	-166	-3676	-1863	7000	5510
CENPK	-7596	-7798	2332	7331	3303
CENPL	-5982	-8049	2744	3755	4081
CENPM	-3068	-1127	3488	4808	3710
CENPN	-7748	-8268	3464	2589	1857
CENPO	-4585	-5217	2243	6228	3869
CENPP	-8987	-5989	4188	-475	-375
CENPQ	-5168	-8986	788	4612	6598
CENPT	-2887	-4406	2029	313	2718
CKAP5	-4894	-8730	4720	1363	835
CLASP1	-5095	-5549	1549	5253	6532
CLASP2	-5060	-3223	-1727	6396	6132
CLIP1	-5995	-5664	2164	-399	4405
DSN1	-2102	-4234	3232	2568	3430
DYNC1H1	-4365	-3256	5029	425	786
DYNC1I2	-6567	-7070	2439	2184	2874
DYNC1LI1	-5010	-1342	2070	1660	915
DYNC1LI2	-3958	-1793	-456	881	-232
DYNLL1	-6435	-1692	4607	677	956
DYNLL2	-1210	-5926	4788	4965	6455
ESPL1	-5611	-8871	2600	5459	8069
INCENP	-4410	-8460	5832	4041	3256
ITGB3BP	-1579	-8699	-2272	7906	4726
KIF18A	-8597	-7811	5152	1274	-189
KIF2A	-1404	-1285	1265	7884	1754
KIF2C	-5335	-4400	4652	5934	7164
KNTC1	-4087	-2381	-2217	7127	5117
MAD1L1	-2169	-893	4397	1233	2279
MAD2L1	-693	-4252	1421	6862	6842
MAPRE1	-6287	-7647	-1239	6750	6392
MIS12	-5040	-5098	3865	137	2565
NDC80	-7727	-3732	4054	3903	88
NDE1	-7104	-8550	191	5467	7621
NDEL1	-3675	-1775	5672	-63	2872
NSL1	-7171	-7994	4556	6255	5553
NUDC	-5765	-4788	5046	1526	3072
NUF2	-4503	-7059	-2397	6976	4190
NUP107	-2367	-5920	902	8020	7981
NUP133	-2192	-6208	-1034	6710	4350
NUP160	-4062	-2126	-1133	5658	7516
NUP37	-7550	-421	4573	1438	1480
NUP43	-5408	-4131	4558	2582	2522
NUP85	-7303	-8224	5526	3668	1520
NUP98	-8199	-889	2149	7764	7066
PAFAH1B1	-5211	-2836	5904	687	-129
PDS5A	-8750	-3459	6341	166	2013
PDS5B	-8826	-3671	4713	-583	3187
PLK1	-4551	-1935	-118	2868	3399
PMF1	-8472	-8813	4661	3508	5960
PPP1CC	383	-760	-109	3143	1760
PPP2CA	-4081	-3471	4425	2847	2701
PPP2CB	-1353	77	5390	-624	-872
PPP2R1B	-1840	-3560	3568	7877	5301
PPP2R5A	-7527	-7188	1532	3085	360
PPP2R5B	-4467	-4603	1078	4371	2363
PPP2R5C	-3793	-9136	3153	2104	6783
PPP2R5D	-2176	-6920	-2111	6390	7682
PPP2R5E	-551	-1739	863	6882	7627
PSMA1	-8359	-8604	5104	1855	4650
PSMA2	-7938	-2161	5110	1432	8018
PSMA3	-2004	-4530	4184	8188	7955
PSMA5	-3753	-5163	4135	7049	6792
PSMA6	-5756	-9052	230	3273	5895
PSMA7	-5963	-1772	3526	2927	3736
PSMB1	-2258	-1758	1218	4974	2620
PSMB10	-1663	-6710	-165	6829	6594
PSMB3	-3839	-6905	4780	5497	4412
PSMB5	-89	-6668	-1101	7598	7952
PSMB6	-6634	-5888	2326	6558	5006
PSMB7	-5105	-6476	-481	6667	7933
PSMB8	-7792	-3686	5160	756	1587
PSMB9	-8032	-7032	4898	3199	1447
PSMC1	89	-6196	611	7227	6270
PSMC3	-4234	-5168	-1757	3247	5525
PSMC4	-5962	-6708	1563	2130	2138
PSMC5	-7766	-7267	5418	2470	428
PSMC6	-7087	-7964	4301	5996	2878
PSMD1	-1790	-8089	458	4661	6182
PSMD11	-1272	-2207	4285	6544	4390
PSMD12	-2535	-3717	20	7015	7973
PSMD13	-8546	-5774	4927	2662	-882
PSMD14	-2548	-5579	3518	3709	4574
PSMD2	-7305	-6402	3485	3621	4835
PSMD3	-6151	-6416	5506	2545	2496
PSMD4	-7964	-5567	754	5325	7149
PSMD6	-4518	-717	1908	2403	114
PSMD7	-3120	-8646	2963	5075	5520
PSMD8	-4369	-5263	1397	3011	5309
PSMD9	-1075	-5374	3215	4605	1840
PSME1	-4828	-2498	2379	209	820
PSME2	-3988	-5227	2344	6844	5159
PSME3	-502	-1677	210	3994	6092
PSME4	-4990	-8991	5997	207	-839
PSMF1	-490	-5529	-2618	4670	8624
PTTG1	-6300	-7345	144	7353	5706
RAD21	-6823	-6698	-54	7352	7315
RANBP2	-3530	-4429	-1283	4903	6045
RANGAP1	-1482	-1294	-174	7332	7247
RCC2	-4789	-1909	3142	1194	346
RPS27A	-6317	-9335	373	8228	8264
SEC13	-8747	-6731	4873	-516	1432
SEH1L	-7723	-5493	4691	844	4470
SKA2	-9013	-5218	2224	8095	7700
SMC3	-5441	-8998	4416	6498	3310
SPC24	-4560	-3857	1317	4230	1955
SPC25	-2804	-6663	-1447	8021	7791
STAG1	-6618	-7770	5829	5087	5078
TAOK1	-5074	-852	6421	1847	383
UBA52	-513	-1242	1530	5448	5828
UBB	-6553	-5964	-13	7418	8036
UBC	-8288	-7011	-1067	5810	7639
UBE2C	-759	-2829	-1688	6275	6660
UBE2D1	-2809	-3007	-157	1866	1336
UBE2E1	-4493	-4384	-1323	3040	2903
XPO1	-6677	-4338	4933	4303	2828
ZW10	-3358	-4465	-133	4675	7777
ZWILCH	-1670	-8800	-1593	8324	8308
ZWINT	-4132	-4213	2506	5868	2166

---

---

Negative regulation of NMDA receptor-mediated neuronal transmission

Negative regulation of NMDA receptor-mediated neuronal transmission

metric	value
setSize	11
pMANOVA	0.000824
p.adjustMANOVA	0.0209
s.dist	0.786
s.psf	0.573
s.psb	0.192
s.hcy	-0.41
s.folate	-0.174
s.vitb12	-0.231
p.psf	0.001
p.psb	0.27
p.hcy	0.0185
p.folate	0.317
p.vitb12	0.185

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	psf	hcy
CAMK1	622	-2658
GRIN1	244	-2485

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
CALM1	-1140	-3090	-703	2569	5919
CAMK1	622	-1001	-2658	4883	-605
CAMK2D	-7602	-2920	6135	-628	-174
CAMK2G	-250	-62	-829	6968	1605
CAMK4	-258	-3558	2726	1835	284
DLG1	-385	-1091	2874	5485	1201
DLG4	-1757	-7935	-1172	5776	4723
GRIN1	244	71	-2485	1161	-555
GRIN2C	-810	-8353	-2408	-394	3376
GRIN2D	-1104	-8108	-2134	1042	7433
PPM1F	-2561	-5038	-1585	302	4984

---

---

Ca-dependent events

Ca-dependent events

metric	value
setSize	21
pMANOVA	0.000871
p.adjustMANOVA	0.0216
s.dist	0.603
s.psf	0.00308
s.psb	0.285
s.hcy	-0.193
s.folate	-0.394
s.vitb12	-0.299
p.psf	0.981
p.psb	0.0236
p.hcy	0.125
p.folate	0.0018
p.vitb12	0.0176

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	folate	vitb12
CAMK2D	-628	-174

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
ADCY4	-4326	-2533	-1935	377	-183
ADCY7	-8384	-9239	-2990	-609	4432
ADCY9	-8670	-84	2546	2727	-326
CALM1	-1140	-3090	-703	2569	5919
CAMK2D	-7602	-2920	6135	-628	-174
CAMK2G	-250	-62	-829	6968	1605
CAMK4	-258	-3558	2726	1835	284
CAMKK1	-5757	-5738	4543	-336	2542
CAMKK2	-3279	-6235	-2051	293	4332
CREB1	-4159	-1226	472	-273	3361
KPNA2	-7476	-5242	4362	3922	198
MAPK1	-2717	-2873	-1146	3217	-292
NBEA	601	-1104	-1866	1043	-263
PDE1B	-2193	-8036	-1367	-308	2187
PRKACA	-4718	-4025	-1287	480	3795
PRKACB	-6646	-908	2348	1167	1023
PRKAR1A	-7139	-2501	4900	-147	424
PRKAR1B	-265	-107	-3015	7076	7451
PRKAR2A	-825	-2422	-2557	771	3315
PRKCA	-5820	-4955	3971	3486	5016
PRKCD	-6607	-1968	5933	-938	2142

---

---

PKA activation

PKA activation

metric	value
setSize	10
pMANOVA	0.00103
p.adjustMANOVA	0.025
s.dist	0.775
s.psf	0.00747
s.psb	0.422
s.hcy	-0.461
s.folate	-0.395
s.vitb12	-0.232
p.psf	0.967
p.psb	0.0208
p.hcy	0.0116
p.folate	0.0304
p.vitb12	0.204

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	hcy	psb

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
ADCY4	-4326	-2533	-1935	377	-183
ADCY7	-8384	-9239	-2990	-609	4432
ADCY9	-8670	-84	2546	2727	-326
CALM1	-1140	-3090	-703	2569	5919
NBEA	601	-1104	-1866	1043	-263
PRKACA	-4718	-4025	-1287	480	3795
PRKACB	-6646	-908	2348	1167	1023
PRKAR1A	-7139	-2501	4900	-147	424
PRKAR1B	-265	-107	-3015	7076	7451
PRKAR2A	-825	-2422	-2557	771	3315

---

---

Heparan sulfate/heparin (HS-GAG) metabolism

Heparan sulfate/heparin (HS-GAG) metabolism

metric	value
setSize	19
pMANOVA	0.00109
p.adjustMANOVA	0.0259
s.dist	0.523
s.psf	0.0637
s.psb	-0.169
s.hcy	-0.349
s.folate	-0.302
s.vitb12	-0.166
p.psf	0.631
p.psb	0.202
p.hcy	0.00839
p.folate	0.0225
p.vitb12	0.211

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	hcy	folate
GPC2	-3049	-1000
HS3ST3B1	-1619	-1051
BCAN	-577	-873
GUSB	-1130	-326

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
AGRN	-1732	-4812	5306	-920	2657
B3GAT2	-2443	-3613	-2451	5231	6322
B3GAT3	-7560	-7514	6080	1057	1402
B4GALT7	385	-2504	-1968	3583	7035
BCAN	-4953	-2674	-577	-873	-799
EXT1	-4322	-7586	-970	441	2492
EXT2	-8207	-6039	1671	-638	-500
GLB1	-4131	-8357	2743	5011	4969
GPC2	650	197	-3049	-1000	2014
GUSB	-5663	-6861	-1130	-326	-253
HPSE2	-3612	-4138	243	3103	6918
HS3ST3B1	-7708	-8583	-1619	-1051	-1127
HS6ST1	-5577	-9138	-2109	175	1589
IDUA	-1386	-7175	-584	6746	1497
NAGLU	-3319	-6080	-1877	2849	1859
NDST2	-4963	-6194	358	2658	6150
SDC4	-217	-2816	-1868	5350	6516
XYLT1	-2213	-6053	-2607	7963	7127
XYLT2	-6636	-4872	6248	-1257	-1042

---

---

Cellular responses to external stimuli

Cellular responses to external stimuli

metric	value
setSize	430
pMANOVA	0.0012
p.adjustMANOVA	0.0279
s.dist	0.113
s.psf	0.00964
s.psb	0.00158
s.hcy	0.0781
s.folate	0.0737
s.vitb12	0.0351
p.psf	0.735
p.psb	0.956
p.hcy	0.00607
p.folate	0.00965
p.vitb12	0.218

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	hcy	folate
EPAS1	6349	7989
CAPZA1	6364	7377
FOS	6620	6248
EP300	4582	8147
TXNIP	4854	7449
PSMA3	4184	8188
WDR24	6397	4896
RPA3	4462	6870
GSK3B	5172	5856
ATM	5395	5612
RPL4	3711	8137
COX11	4571	6567
RPL41	4115	7287
ATP6V1C1	4518	6598
NUP205	4686	6267
PSMA5	4135	7049
TNRC6B	4883	5846
HMGA1	4669	6077
UBE2D3	3581	7910
ATP6V0E1	5107	5545

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
AAAS	-4813	-3658	2354	1828	2776
ABCC1	-340	-1988	-468	7984	2125
ACD	-4066	-313	3133	-1249	-913
ACTR10	-5379	-2564	5211	4749	1918
ACTR1A	-7409	-7285	6228	2166	2934
AKT1S1	-6014	-4204	4892	4560	3462
ANAPC1	-4888	-4370	4561	5142	1218
ANAPC10	-404	-8610	-361	6447	2473
ANAPC11	-1837	-244	601	4297	4855
ANAPC2	-5187	-4944	5252	-135	-940
ANAPC4	-1773	-8700	4698	4531	5293
ANAPC5	-2266	-8728	1095	6000	7040
ANAPC7	-3940	-8396	2305	7272	5608
APOA1	-7646	-7159	1479	2996	26
ARNT	-1050	-3672	1230	5259	6747
ARNTL	-5169	-1447	413	3086	7286
ASNS	-4354	-555	3289	1003	753
ATF3	-1449	-1825	-731	4764	4613
ATF4	-6404	-9161	5649	-136	-472
ATM	-8275	-7820	5395	5612	5420
ATOX1	-5644	-4346	5890	-297	-240
ATP6V0B	-7452	-1006	4033	214	-858
ATP6V0C	-556	-2680	-2828	3869	1352
ATP6V0D1	-3499	-2151	3369	1750	2485
ATP6V0E1	-5753	-5829	5107	5545	2249
ATP6V0E2	-970	-2187	-2997	4105	7563
ATP6V1A	-8528	-8015	4569	4317	605
ATP6V1B2	-6568	-3841	-1144	1247	3694
ATP6V1C1	-567	-7013	4518	6598	4656
ATP6V1E1	-2421	-6611	613	8262	7479
ATP6V1F	-252	-1893	2531	5882	8175
ATP6V1G2	-9097	-5621	763	7718	8016
ATP6V1H	-1687	-4122	-409	3576	5224
ATR	-7759	-7294	5030	3018	2218
BACH1	549	-1443	-473	-508	5708
BAG2	-5290	-3302	-1616	3589	8013
BAG3	-8136	-5149	3829	856	918
BAG4	-8027	-1984	1154	4204	2366
BAG5	-5195	-515	1250	-1170	1322
BLVRA	-4801	-847	3693	-1190	-965
BLVRB	-8149	-2186	-2908	-1116	-1179
BMI1	67	-3601	-2400	1115	4852
C12orf66	-1680	-1879	13	4843	5180
CABIN1	-6741	-6457	6468	2079	-319
CAMK2D	-7602	-2920	6135	-628	-174
CAMK2G	-250	-62	-829	6968	1605
CAPZA1	322	-9142	6364	7377	-943
CAPZA2	-1348	-1720	3606	5221	7185
CAPZB	-107	-904	-1687	5269	2944
CAT	477	-544	573	2534	6713
CBX4	-1709	-6954	-659	3637	6241
CBX6	-7000	-7981	6483	146	-910
CBX8	-8609	-449	5928	3266	444
CCNA2	-6844	-7471	3487	2247	4856
CCNE1	525	-3003	-755	1514	7279
CCNE2	-3810	-2459	4526	-177	568
CCS	-5288	-9042	-1157	7108	6561
CDC16	-1108	-909	-2388	2815	1317
CDC23	-1180	-4858	84	8244	8117
CDK2	-3067	-9380	1071	8170	2476
CDK4	-5104	-3263	1863	4831	3952
CDK6	-1505	-5601	3867	3476	2214
CDKN1A	-1859	-8647	-682	379	-950
CDKN1B	-6280	-4166	4449	4561	3488
CDKN2A	-1603	-4829	-1553	-652	3818
CDKN2C	-1733	-6562	242	1412	5472
CDKN2D	-3062	-1885	3696	3381	6513
CEBPB	-1913	-3140	3325	2973	4936
CEBPG	-175	-2309	-1289	4256	5740
CHAC1	-7839	-5827	4762	3535	-209
CHD9	-5009	-1522	-612	3889	5338
CITED2	-6940	-7599	5053	1324	3665
CLOCK	-4455	-1545	99	4719	5714
COX11	-5435	-3736	4571	6567	1012
COX16	-5641	-7884	950	7504	6975
COX19	-6020	-6417	369	1393	3300
COX5A	-1730	-4669	-1310	4144	5481
COX5B	-3551	-3965	2006	7151	6865
COX6A1	-867	-7163	1268	6383	4032
COX6B1	-1491	-5188	-732	6962	8216
COX6C	-7936	-8942	3884	-513	2985
COX7A2L	-8868	-3000	1597	2482	7694
COX7C	-5100	-5924	1879	4772	5704
COX8A	-5724	-5857	880	6491	5184
CREB1	-4159	-1226	472	-273	3361
CREBBP	493	7	-2526	2622	8628
CRTC1	-122	-2273	525	2561	1772
CRTC2	-7075	-4865	4099	4404	6868
CRTC3	238	-2	5695	176	2669
CSNK2A2	-276	-6345	-188	5902	-421
CSNK2B	-8437	-8556	3108	982	975
CSRP1	-7830	-861	3345	54	128
CUL1	697	205	-2993	1565	8112
CUL2	-6279	-4347	4648	4094	359
CUL3	-6281	-2196	3475	-1057	1298
CYBA	-1389	-6143	3156	3491	3666
CYCS	-6191	-2897	1651	2816	5215
DCTN2	-3373	-6548	-2552	7412	7292
DCTN3	-8835	-5606	5566	4936	7213
DCTN4	-2893	-8487	312	7432	7459
DCTN5	-7165	-5448	3216	473	-32
DCTN6	-4909	-3795	1667	1332	4296
DDIT3	-5917	-8203	3407	-459	650
DEDD2	-2701	-3169	3797	4838	3381
DEPDC5	-3444	-7696	-2320	1410	4250
DNAJA1	-93	132	-1827	7499	6261
DNAJA2	275	-2181	1698	6273	-273
DNAJA4	-6232	207	6694	-226	754
DNAJB1	-4227	-6647	377	3390	1990
DNAJB6	-7685	-6871	5304	-735	573
DNAJC2	97	-5426	-358	8135	5980
DYNC1H1	-4365	-3256	5029	425	786
DYNC1I2	-6567	-7070	2439	2184	2874
DYNC1LI1	-5010	-1342	2070	1660	915
DYNC1LI2	-3958	-1793	-456	881	-232
DYNLL1	-6435	-1692	4607	677	956
DYNLL2	-1210	-5926	4788	4965	6455
E2F1	-4735	-1187	2003	924	6888
E2F2	-3044	-4814	3131	3050	3652
E2F3	-2379	-4496	-1726	7813	7614
EED	-8844	-8560	4593	4771	6631
EEF1A1	-3918	-942	2202	3605	6293
EGLN1	-60	-5871	-2124	8223	7944
EGLN2	-2843	-5439	4458	4046	2177
EHMT1	-12	-5791	328	2017	1333
EHMT2	-7541	-7444	3294	5245	5712
EIF2AK1	-7230	-8122	2416	5852	5153
EIF2AK4	-6058	-5930	2320	1957	2309
EIF2S1	-2735	-7410	-1488	6910	7442
EIF2S2	-8040	-2246	4352	4264	1966
EP300	-1930	-7100	4582	8147	5387
EP400	484	-461	4622	5120	2610
EPAS1	-8483	-5156	6349	7989	4569
ERF	-4985	-5458	3608	4005	2664
ETS1	-7449	-7744	5601	1125	2169
ETS2	-4893	-1349	-1495	3857	721
EZH2	-4051	-7225	5422	2942	7416
FAU	-7265	-3975	4740	233	1443
FBXL17	-2337	-5524	3311	6515	1773
FKBP4	-1969	-5456	2181	3069	2487
FKBP5	-3625	-7627	4717	1106	2235
FLCN	-1711	-2578	1818	6363	4260
FNIP1	-5455	-7316	4455	3081	3342
FOS	-8502	-9581	6620	6248	7506
FZR1	-640	-846	4578	-149	3801
GATSL3	-3237	-5756	-1321	7513	4501
GPX1	-3550	-5627	130	4782	1013
GRB10	675	-561	-1415	4276	4197
GSK3B	-1534	-6592	5172	5856	3113
GSR	-2205	-172	4383	285	1466
GSTP1	-326	-691	-2505	712	3156
H2AFX	-2264	-828	-738	1976	3608
HDAC3	-9055	-9330	6558	230	-121
HIF1A	-7062	-4150	5397	-78	1184
HIF1AN	-1301	-1400	1299	5789	841
HIGD1A	-2038	-3440	896	3895	202
HIRA	-1987	-39	1044	360	2884
HM13	-2048	-1966	-2537	800	6306
HMGA1	-7018	-1560	4669	6077	2296
HMOX2	-141	-575	2624	4799	4252
HSBP1	189	-1900	-2748	5163	6151
HSF1	490	-9422	-2169	4986	1489
HSP90AA1	-1474	-2948	4393	938	5308
HSP90AB1	-6037	-9040	-1669	7956	8086
HSPA13	-5580	-8222	4649	5794	7518
HSPA14	82	-8574	-988	5724	8425
HSPA1A	-8087	-7146	832	3274	3761
HSPA1B	-4452	-4831	5474	3271	1652
HSPA1L	-7811	-6206	3350	6071	5134
HSPA2	-8530	-5139	6296	1465	150
HSPA4	-5353	-356	5240	668	1932
HSPA4L	-8085	-2728	-1472	6423	4415
HSPA9	-5213	-1958	1744	1649	1753
HSPH1	-8905	-7450	4860	2620	604
ID1	-2473	-1630	3279	156	588
ITFG2	-7522	-6667	4923	4624	4118
JUN	-6776	-4272	3366	5820	1877
KAT5	-7746	-4286	3717	4016	3371
KDM6B	-8034	-4837	6246	893	386
KEAP1	-1322	-591	-357	3852	6237
KPTN	-4400	-5154	5359	2907	3021
LIMD1	-3141	-6803	1326	102	3655
LMNB1	-7257	-5018	3817	4000	853
LRPPRC	-4961	-2405	1190	3407	7367
MAFK	-714	-1847	-2057	5960	5148
MAP2K3	-577	-6000	-511	7845	6935
MAP2K4	-6526	-3031	4063	74	2710
MAP2K6	-5401	-9451	4916	2846	7797
MAP2K7	-2470	-645	5221	2695	6109
MAP3K5	-4609	-7123	-1855	503	2941
MAP4K4	-203	-3423	4307	1504	4107
MAPK1	-2717	-2873	-1146	3217	-292
MAPK14	-7648	-3775	1942	1668	1054
MAPK3	-6889	-9407	-1492	8081	6172
MAPK7	-4367	-2784	5377	5187	5682
MAPK9	-844	-1217	-75	523	1058
MAPKAPK2	-6467	-6863	2498	2575	888
MAPKAPK3	-8353	-5254	6059	-307	-594
MDM2	-7427	-3880	5322	1489	4370
MDM4	-7073	-6259	4702	2640	5555
MED1	438	-491	-1355	7088	7424
MEF2D	-4997	-1942	-1583	4899	3276
MINK1	-8882	-5766	6097	4429	2824
MIOS	-7928	-7769	6014	3424	1036
MLST8	-8369	-6085	1877	-364	-70
MOV10	462	-4832	-2848	8151	7977
MRPL18	-4852	-5844	4786	2600	5318
MT1F	-865	-9065	2586	4966	5529
MT1X	-8019	-8246	1206	-334	-403
MT2A	-3998	-4789	-149	2752	2867
MTF1	-4608	-8783	-50	2656	971
MTOR	-1522	-7624	213	6768	6238
NBN	-3696	-7848	771	7212	5058
NCF4	447	-228	-3102	7926	6586
NCOA2	-2507	-322	4839	-1083	2427
NCOA6	-2318	-77	4775	4117	4801
NCOR1	131	-1246	-1234	2574	280
NCOR2	257	-154	-2696	6978	4125
NDUFA4	-6747	-2769	4324	3990	4883
NFE2L2	-3262	-7196	1041	6320	4104
NLRP3	-3651	-9524	-3052	6264	8225
NR1D1	-5550	-5486	2675	2544	116
NR3C1	-5717	-4190	5002	3820	3029
NR3C2	-7773	-7758	6403	1291	-544
NUDT2	-5456	-2020	6336	2955	-1120
NUP107	-2367	-5920	902	8020	7981
NUP133	-2192	-6208	-1034	6710	4350
NUP153	-4611	-8419	2123	1709	5952
NUP155	-938	-2261	778	3101	6606
NUP160	-4062	-2126	-1133	5658	7516
NUP188	-4111	-2994	3510	3714	3909
NUP205	-8245	-8394	4686	6267	6798
NUP210	-8192	-8465	2605	2001	-159
NUP214	-3272	-1704	2474	2228	1116
NUP35	-1551	-7219	-1373	8140	8243
NUP37	-7550	-421	4573	1438	1480
NUP43	-5408	-4131	4558	2582	2522
NUP50	-4714	-688	2999	1921	1935
NUP54	-1931	-4958	3515	3754	3208
NUP62	-1453	-8038	1978	7023	5407
NUP85	-7303	-8224	5526	3668	1520
NUP93	-3267	-3790	-2168	3175	6994
NUP98	-8199	-889	2149	7764	7066
P4HB	-5071	-606	2641	1394	3861
PHC1	-7943	-634	-51	-665	1715
PHC2	327	-5626	4838	-1206	268
PHC3	-5127	-3528	2183	3209	5821
POM121	-6127	-7922	5593	4069	6325
POM121C	-3786	-5219	3938	5072	3069
PPP1R15A	-1922	-1371	-1148	1777	7112
PRDX1	-2592	-6678	2169	7162	7386
PRDX2	-362	-1430	-885	3342	1366
PRDX3	589	-2507	753	8311	6286
PRDX5	-5684	-3972	3801	4783	2005
PRDX6	-1920	-3917	5689	1434	2846
PRKCD	-6607	-1968	5933	-938	2142
PSMA1	-8359	-8604	5104	1855	4650
PSMA2	-7938	-2161	5110	1432	8018
PSMA3	-2004	-4530	4184	8188	7955
PSMA5	-3753	-5163	4135	7049	6792
PSMA6	-5756	-9052	230	3273	5895
PSMA7	-5963	-1772	3526	2927	3736
PSMB1	-2258	-1758	1218	4974	2620
PSMB10	-1663	-6710	-165	6829	6594
PSMB3	-3839	-6905	4780	5497	4412
PSMB5	-89	-6668	-1101	7598	7952
PSMB6	-6634	-5888	2326	6558	5006
PSMB7	-5105	-6476	-481	6667	7933
PSMB8	-7792	-3686	5160	756	1587
PSMB9	-8032	-7032	4898	3199	1447
PSMC1	89	-6196	611	7227	6270
PSMC3	-4234	-5168	-1757	3247	5525
PSMC4	-5962	-6708	1563	2130	2138
PSMC5	-7766	-7267	5418	2470	428
PSMC6	-7087	-7964	4301	5996	2878
PSMD1	-1790	-8089	458	4661	6182
PSMD11	-1272	-2207	4285	6544	4390
PSMD12	-2535	-3717	20	7015	7973
PSMD13	-8546	-5774	4927	2662	-882
PSMD14	-2548	-5579	3518	3709	4574
PSMD2	-7305	-6402	3485	3621	4835
PSMD3	-6151	-6416	5506	2545	2496
PSMD4	-7964	-5567	754	5325	7149
PSMD6	-4518	-717	1908	2403	114
PSMD7	-3120	-8646	2963	5075	5520
PSMD8	-4369	-5263	1397	3011	5309
PSMD9	-1075	-5374	3215	4605	1840
PSME1	-4828	-2498	2379	209	820
PSME2	-3988	-5227	2344	6844	5159
PSME3	-502	-1677	210	3994	6092
PSME4	-4990	-8991	5997	207	-839
PSMF1	-490	-5529	-2618	4670	8624
PTGES3	-2862	-6925	6314	2982	4506
RAD50	-2315	-2352	2399	2091	556
RAE1	-8303	-1469	2950	2287	4628
RAI1	-3134	-4362	-1201	4178	6826
RANBP2	-3530	-4429	-1283	4903	6045
RB1	-3440	-7436	2475	4145	2659
RBBP4	-1926	-4404	290	4089	6722
RBX1	-8553	-7492	5617	651	240
RELA	100	-4011	-1231	7858	5204
RHEB	-8809	-4716	2271	702	-1069
RING1	-4180	-1816	1769	4664	3253
RNF2	-7298	-8232	5910	-824	7385
RORA	-3243	-1036	5488	901	949
RPA1	-4921	-4495	1606	6872	2672
RPA3	-7347	-4983	4462	6870	6874
RPL10A	-7961	-6516	5455	-562	-314
RPL11	-7677	-8167	3810	4330	1988
RPL13	-6639	-6581	4655	339	-537
RPL14	-3052	-5425	5360	2209	2012
RPL15	-27	-8740	-2423	7772	8423
RPL17	563	-3865	-480	4433	8207
RPL18	-2631	-3772	1752	2150	3906
RPL22	-947	-2943	1781	5041	7376
RPL23	-7653	-8875	3169	6505	7202
RPL23A	522	-8791	-1715	1098	8574
RPL26	-4372	-1563	1337	7225	4877
RPL26L1	-4818	-2012	666	7153	5923
RPL27A	-2593	-5880	1519	5614	3407
RPL28	-2550	-8709	1296	7634	8337
RPL29	-7865	-8348	4990	5290	3398
RPL3	124	-684	3364	7916	2714
RPL31	-1156	-1527	5771	3555	5759
RPL32	-6814	-5379	2458	6861	8038
RPL34	-5271	-2482	1552	7954	8213
RPL35	-7512	-6777	2622	1903	799
RPL36	-446	-8044	2924	4617	5662
RPL36AL	-2554	-1327	5773	-1188	-452
RPL37	-488	-4156	2639	6405	2890
RPL37A	-6905	-9008	1174	6591	8046
RPL38	-2316	-4031	-629	7481	4924
RPL39L	-6999	-607	5706	485	-372
RPL4	-464	1	3711	8137	2147
RPL41	-6769	-7390	4115	7287	7829
RPL6	-8649	-7260	1906	4621	6508
RPL7	617	-9286	4967	2139	-293
RPL8	-4954	-5065	5868	-295	2695
RPL9	-3855	-8612	-1663	7462	8503
RPLP0	-1480	-5182	4527	3049	1985
RPLP1	356	-946	-2185	3408	5124
RPLP2	-1698	-4673	2663	1447	1945
RPS10	-3722	-3808	3900	5908	5830
RPS11	-6672	-6883	6042	2201	549
RPS12	-4513	-4913	2813	3328	2047
RPS15	-4634	-433	2414	1135	1071
RPS15A	-4474	-6721	5624	72	-33
RPS16	-3896	-5372	1615	6351	8153
RPS18	27	-4521	-105	5632	5497
RPS19	-8382	-6907	1660	2666	3451
RPS19BP1	-8448	-6834	2764	2023	2015
RPS20	-297	-1255	-114	7538	3627
RPS23	-4251	-9223	2178	6550	6652
RPS24	-1372	-9105	131	7985	8504
RPS25	-3315	-4836	393	8288	7689
RPS26	-5021	-7689	3830	2822	5603
RPS27A	-6317	-9335	373	8228	8264
RPS27L	-3683	-4732	5057	4151	4066
RPS28	-8455	-9366	2374	8167	7739
RPS29	-3873	-6709	4263	5166	7494
RPS3	684	-239	2229	8185	4487
RPS3A	-1807	-1288	3771	4514	7401
RPS5	-6359	-7892	4030	1210	3970
RPS6	-4056	-9376	2203	8168	6880
RPS6KA1	-5437	-3891	-2723	-627	1954
RPS6KA2	-5884	-402	3112	3010	3312
RPS7	91	-6394	2759	2356	2340
RPS8	263	-6446	-2966	5562	-1225
RPS9	-3698	-1350	3516	4648	5321
RPSA	-7318	-8950	374	8071	8168
RPTOR	-710	-706	4723	3819	1986
RRAGA	-7852	-7960	-2144	-558	-524
RRAGC	-1516	-3639	-234	7226	7584
RRAGD	-3672	-1495	-1951	7231	5962
SCMH1	-6319	-3234	-1156	-1366	532
SCO1	-4730	-6138	6503	3255	218
SCO2	-4238	-160	-1569	2147	1139
SEC13	-8747	-6731	4873	-516	1432
SEH1L	-7723	-5493	4691	844	4470
SERPINH1	-3308	-6565	436	5737	3238
SESN1	-7052	-7620	-108	3760	5142
SESN2	-6557	-5030	2854	2636	581
SIN3A	-3756	-6339	592	7416	5305
SIN3B	-5728	-6577	4958	4540	8349
SIRT1	-4482	-5574	-1480	1164	4588
SKP1	-1797	-7721	6201	2774	2018
SKP2	-1150	-8814	-743	7917	8093
SLC38A9	-6647	-7447	5307	-774	509
SOD1	-4942	-4268	580	5875	2227
SOD2	-48	-5922	2479	4301	5703
SP1	-8205	-6021	4034	2297	2451
ST13	-7141	-201	1543	4655	4194
STAT3	-3331	-987	2282	6265	6816
STIP1	-7004	-5727	4236	3689	6906
SURF1	-5536	-1734	5443	2676	-686
TACO1	-8537	-5891	1634	4509	2124
TBL1XR1	-5330	-680	4052	4546	2292
TCIRG1	-3406	-1528	-2103	6845	4525
TERF1	-4657	-5906	936	5088	3646
TERF2	-8117	-8978	1787	2541	1152
TERF2IP	-3819	-8159	5281	1951	676
TFDP1	191	-2894	-2589	638	513
TINF2	-8428	-6625	5012	-23	-8
TNIK	-925	-6245	3505	4614	6196
TNRC6A	-5935	-4254	5456	4870	6042
TNRC6B	-5203	-6029	4883	5846	3955
TP53	-3124	-9254	3539	7152	6754
TPR	-1912	-1701	2275	6893	903
TRIB3	-780	-6700	-1072	2683	5446
TXN	-7099	-7476	1364	7676	6700
TXN2	-5354	-2406	-2050	4994	7435
TXNIP	-7152	-5823	4854	7449	7537
TXNRD1	175	-4239	-513	6429	8167
TXNRD2	-2178	-2021	4773	2434	-765
UBA52	-513	-1242	1530	5448	5828
UBB	-6553	-5964	-13	7418	8036
UBC	-8288	-7011	-1067	5810	7639
UBE2C	-759	-2829	-1688	6275	6660
UBE2D1	-2809	-3007	-157	1866	1336
UBE2D2	-6363	-1008	5167	-393	-568
UBE2D3	-4755	-7137	3581	7910	2953
UBE2E1	-4493	-4384	-1323	3040	2903
UBN1	-354	-1526	1162	7721	4677
VCP	-4088	-3661	-905	7139	8260
VEGFA	-2139	-4266	73	5304	4047
VHL	-2603	-4287	1575	4912	6757
WDR24	-6682	-2454	6397	4896	1607
WDR59	205	-1009	-781	2538	1826
XPO1	-6677	-4338	4933	4303	2828
YWHAE	138	-1017	-2211	1240	4019

---

---

Defective CFTR causes cystic fibrosis

Defective CFTR causes cystic fibrosis

metric	value
setSize	51
pMANOVA	0.00126
p.adjustMANOVA	0.0286
s.dist	0.4
s.psf	-0.0848
s.psb	-0.159
s.hcy	0.0433
s.folate	0.239
s.vitb12	0.262
p.psf	0.295
p.psb	0.0496
p.hcy	0.594
p.folate	0.00316
p.vitb12	0.00122

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	vitb12	folate
RNF5	8618	8413
DERL2	8611	8395
RPS27A	8264	8228
SEL1L	8335	7981
PSMA3	7955	8188
PSMB5	7952	7598
UBB	8036	7418
VCP	8260	7139
PSMD12	7973	7015
RNF185	7182	7441
PSMB7	7933	6667
PSMA5	6792	7049
PSMC1	6270	7227
PSMB10	6594	6829
UBC	7639	5810
ERLIN2	7696	5549
PSMF1	8624	4670
PSMD4	7149	5325
PSME2	5159	6844
PSMB6	5006	6558

Click HERE to show all gene set members

All member genes

	psf	psb	hcy	folate	vitb12
DERL1	-7525	-4174	5525	1574	4926
DERL2	-6378	-1078	-2905	8395	8611
DERL3	-5309	-6924	1573	287	223
ERLEC1	-3907	-179	6714	-1438	1154
ERLIN1	-2992	-8315	3349	4762	4223
ERLIN2	-3036	-3359	-1025	5549	7696
OS9	-7631	-6146	1976	6158	4228
PSMA1	-8359	-8604	5104	1855	4650
PSMA2	-7938	-2161	5110	1432	8018
PSMA3	-2004	-4530	4184	8188	7955
PSMA5	-3753	-5163	4135	7049	6792
PSMA6	-5756	-9052	230	3273	5895
PSMA7	-5963	-1772	3526	2927	3736
PSMB1	-2258	-1758	1218	4974	2620
PSMB10	-1663	-6710	-165	6829	6594
PSMB3	-3839	-6905	4780	5497	4412
PSMB5	-89	-6668	-1101	7598	7952
PSMB6	-6634	-5888	2326	6558	5006
PSMB7	-5105	-6476	-481	6667	7933
PSMB8	-7792	-3686	5160	756	1587
PSMB9	-8032	-7032	4898	3199	1447
PSMC1	89	-6196	611	7227	6270
PSMC3	-4234	-5168	-1757	3247	5525
PSMC4	-5962	-6708	1563	2130	2138
PSMC5	-7766	-7267	5418	2470	428
PSMC6	-7087	-7964	4301	5996	2878
PSMD1	-1790	-8089	458	4661	6182
PSMD11	-1272	-2207	4285	6544	4390
PSMD12	-2535	-3717	20	7015	7973
PSMD13	-8546	-5774	4927	2662	-882
PSMD14	-2548	-5579	3518	3709	4574
PSMD2	-7305	-6402	3485	3621	4835
PSMD3	-6151	-6416	5506	2545	2496
PSMD4	-7964	-5567	754	5325	7149
PSMD6	-4518	-717	1908	2403	114
PSMD7	-3120	-8646	2963	5075	5520
PSMD8	-4369	-5263	1397	3011	5309
PSMD9	-1075	-5374	3215	4605	1840
PSME1	-4828	-2498	2379	209	820
PSME2	-3988	-5227	2344	6844	5159
PSME3	-502	-1677	210	3994	6092
PSME4	-4990	-8991	5997	207	-839
PSMF1	-490	-5529	-2618	4670	8624
RNF185	-3254	-6575	2141	7441	7182
RNF5	-2787	-9509	-1809	8413	8618
RPS27A	-6317	-9335	373	8228	8264
SEL1L	-6115	-7821	-1714	7981	8335
UBA52	-513	-1242	1530	5448	5828
UBB	-6553	-5964	-13	7418	8036
UBC	-8288	-7011	-1067	5810	7639
VCP	-4088	-3661	-905	7139	8260

---

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.1.0 (2021-05-18)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 20.04.2 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/liblapack.so.3
## 
## locale:
##  [1] LC_CTYPE=en_AU.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_AU.UTF-8        LC_COLLATE=en_AU.UTF-8    
##  [5] LC_MONETARY=en_AU.UTF-8    LC_MESSAGES=en_AU.UTF-8   
##  [7] LC_PAPER=en_AU.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_AU.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
##  [1] grid      stats4    parallel  stats     graphics  grDevices utils    
##  [8] datasets  methods   base     
## 
## other attached packages:
##  [1] pkgload_1.2.1                                      
##  [2] GGally_2.1.1                                       
##  [3] ggplot2_3.3.3                                      
##  [4] gtools_3.8.2                                       
##  [5] tibble_3.1.2                                       
##  [6] dplyr_1.0.6                                        
##  [7] echarts4r_0.4.0                                    
##  [8] ENmix_1.25.1                                       
##  [9] doParallel_1.0.16                                  
## [10] qqman_0.1.8                                        
## [11] RCircos_1.2.1                                      
## [12] DMRcatedata_2.6.0                                  
## [13] ExperimentHub_1.14.2                               
## [14] AnnotationHub_2.20.2                               
## [15] BiocFileCache_1.12.1                               
## [16] dbplyr_2.1.1                                       
## [17] beeswarm_0.3.1                                     
## [18] reshape2_1.4.4                                     
## [19] gplots_3.1.1                                       
## [20] eulerr_6.1.0                                       
## [21] R.utils_2.10.1                                     
## [22] R.oo_1.24.0                                        
## [23] R.methodsS3_1.8.1                                  
## [24] plyr_1.8.6                                         
## [25] RColorBrewer_1.1-2                                 
## [26] forestplot_1.10.1                                  
## [27] checkmate_2.0.0                                    
## [28] magrittr_2.0.1                                     
## [29] kableExtra_1.3.4                                   
## [30] mitch_1.0.10                                       
## [31] DMRcate_2.2.3                                      
## [32] IlluminaHumanMethylation450kmanifest_0.4.0         
## [33] topconfects_1.4.0                                  
## [34] limma_3.44.3                                       
## [35] GEOquery_2.56.0                                    
## [36] missMethyl_1.22.0                                  
## [37] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [38] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.0 
## [39] minfi_1.34.0                                       
## [40] bumphunter_1.30.0                                  
## [41] locfit_1.5-9.4                                     
## [42] iterators_1.0.13                                   
## [43] foreach_1.5.1                                      
## [44] Biostrings_2.56.0                                  
## [45] XVector_0.28.0                                     
## [46] SummarizedExperiment_1.18.2                        
## [47] DelayedArray_0.14.1                                
## [48] matrixStats_0.58.0                                 
## [49] Biobase_2.48.0                                     
## [50] GenomicRanges_1.40.0                               
## [51] GenomeInfoDb_1.24.2                                
## [52] IRanges_2.22.2                                     
## [53] S4Vectors_0.26.1                                   
## [54] BiocGenerics_0.34.0                                
## 
## loaded via a namespace (and not attached):
##   [1] rappdirs_0.3.3                rtracklayer_1.48.0           
##   [3] tidyr_1.1.3                   bit64_4.0.5                  
##   [5] knitr_1.33                    data.table_1.14.0            
##   [7] rpart_4.1-15                  RCurl_1.98-1.3               
##   [9] AnnotationFilter_1.12.0       generics_0.1.0               
##  [11] GenomicFeatures_1.40.1        preprocessCore_1.50.0        
##  [13] RSQLite_2.2.7                 bit_4.0.4                    
##  [15] webshot_0.5.2                 xml2_1.3.2                   
##  [17] httpuv_1.6.1                  assertthat_0.2.1             
##  [19] xfun_0.23                     hms_1.1.0                    
##  [21] jquerylib_0.1.4               evaluate_0.14                
##  [23] promises_1.2.0.1              fansi_0.4.2                  
##  [25] scrime_1.3.5                  progress_1.2.2               
##  [27] caTools_1.18.2                readxl_1.3.1                 
##  [29] DBI_1.1.1                     geneplotter_1.66.0           
##  [31] htmlwidgets_1.5.3             reshape_0.8.8                
##  [33] purrr_0.3.4                   ellipsis_0.3.2               
##  [35] backports_1.2.1               permute_0.9-5                
##  [37] calibrate_1.7.7               annotate_1.66.0              
##  [39] biomaRt_2.44.4                vctrs_0.3.8                  
##  [41] ensembldb_2.12.1              withr_2.4.2                  
##  [43] cachem_1.0.5                  Gviz_1.32.0                  
##  [45] BSgenome_1.56.0               GenomicAlignments_1.24.0     
##  [47] prettyunits_1.1.1             mclust_5.4.7                 
##  [49] svglite_2.0.0                 cluster_2.1.2                
##  [51] RPMM_1.25                     lazyeval_0.2.2               
##  [53] crayon_1.4.1                  genefilter_1.70.0            
##  [55] labeling_0.4.2                edgeR_3.30.3                 
##  [57] pkgconfig_2.0.3               nlme_3.1-152                 
##  [59] ProtGenerics_1.20.0           nnet_7.3-16                  
##  [61] rlang_0.4.11                  lifecycle_1.0.0              
##  [63] dichromat_2.0-0               rprojroot_2.0.2              
##  [65] cellranger_1.1.0              rngtools_1.5                 
##  [67] base64_2.0                    Matrix_1.3-3                 
##  [69] Rhdf5lib_1.10.1               base64enc_0.1-3              
##  [71] png_0.1-7                     viridisLite_0.4.0            
##  [73] bitops_1.0-7                  KernSmooth_2.23-20           
##  [75] blob_1.2.1                    DelayedMatrixStats_1.10.1    
##  [77] doRNG_1.8.2                   stringr_1.4.0                
##  [79] nor1mix_1.3-0                 readr_1.4.0                  
##  [81] jpeg_0.1-8.1                  scales_1.1.1                 
##  [83] lpSolve_5.6.15                memoise_2.0.0                
##  [85] zlibbioc_1.34.0               compiler_4.1.0               
##  [87] illuminaio_0.30.0             Rsamtools_2.4.0              
##  [89] DSS_2.36.0                    htmlTable_2.2.1              
##  [91] Formula_1.2-4                 MASS_7.3-54                  
##  [93] tidyselect_1.1.1              stringi_1.6.2                
##  [95] highr_0.9                     yaml_2.2.1                   
##  [97] askpass_1.1                   latticeExtra_0.6-29          
##  [99] sass_0.4.0                    VariantAnnotation_1.34.0     
## [101] tools_4.1.0                   rstudioapi_0.13              
## [103] foreign_0.8-81                bsseq_1.24.4                 
## [105] gridExtra_2.3                 farver_2.1.0                 
## [107] digest_0.6.27                 BiocManager_1.30.15          
## [109] shiny_1.6.0                   quadprog_1.5-8               
## [111] Rcpp_1.0.6                    siggenes_1.62.0              
## [113] BiocVersion_3.11.1            later_1.2.0                  
## [115] org.Hs.eg.db_3.11.4           httr_1.4.2                   
## [117] AnnotationDbi_1.50.3          biovizBase_1.36.0            
## [119] colorspace_2.0-1              rvest_1.0.0                  
## [121] XML_3.99-0.6                  splines_4.1.0                
## [123] statmod_1.4.36                multtest_2.44.0              
## [125] irr_0.84.1                    systemfonts_1.0.2            
## [127] xtable_1.8-4                  jsonlite_1.7.2               
## [129] dynamicTreeCut_1.63-1         testthat_3.0.2               
## [131] R6_2.5.0                      Hmisc_4.5-0                  
## [133] pillar_1.6.1                  htmltools_0.5.1.1            
## [135] mime_0.10                     glue_1.4.2                   
## [137] fastmap_1.1.0                 BiocParallel_1.22.0          
## [139] interactiveDisplayBase_1.26.3 beanplot_1.2                 
## [141] codetools_0.2-18              utf8_1.2.1                   
## [143] lattice_0.20-44               bslib_0.2.5.1                
## [145] curl_4.3.1                    openssl_1.4.4                
## [147] survival_3.2-11               rmarkdown_2.8                
## [149] desc_1.3.0                    munsell_0.5.0                
## [151] rhdf5_2.32.4                  GenomeInfoDbData_1.2.3       
## [153] HDF5Array_1.16.1              impute_1.62.0                
## [155] gtable_0.3.0

END of report