date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch
x
A1BG -0.0008826
A1BG-AS1 -0.0026734
A1CF 0.0055165
A2M 0.0025986
A2M-AS1 0.0105620
A2ML1 0.0035716

Here are some metrics about the input data profile:

Profiling data metrics
Profile metrics
num_genesets 1654
num_genes_in_profile 22007
duplicated_genes_present 0
num_profile_genes_in_sets 10383
num_profile_genes_not_in_sets 11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt
Gene set metrics
Gene sets metrics
num_genesets 1654
num_genesets_excluded 365
num_genesets_included 1289

Differential pathway expression


Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

## Warning in kable_styling(., "hover", full_width = FALSE): Please specify format
## in kable. kableExtra can customize either HTML or LaTeX outputs. See
## https://haozhu233.github.io/kableExtra/ for details.
set setSize pANOVA s.dist p.adjustANOVA
REACTOME SENSORY PERCEPTION 555 7.47e-32 0.2910 1.23e-28
REACTOME OLFACTORY SIGNALING PATHWAY 348 1.02e-29 0.3530 8.34e-27
REACTOME KERATINIZATION 210 2.20e-21 0.3800 1.20e-18
REACTOME NEUTROPHIL DEGRANULATION 460 4.79e-21 -0.2560 1.96e-18
REACTOME CELLULAR RESPONSES TO STIMULI 779 6.41e-18 -0.1820 2.10e-15
REACTOME FORMATION OF THE CORNIFIED ENVELOPE 125 1.02e-17 0.4440 2.79e-15
REACTOME RNA POLYMERASE II TRANSCRIPTION 1336 7.46e-16 -0.1310 1.75e-13
REACTOME CELL CYCLE MITOTIC 539 1.97e-15 -0.2000 4.04e-13
REACTOME CELL CYCLE 666 2.24e-15 -0.1800 4.09e-13
REACTOME CELLULAR SENESCENCE 189 1.67e-14 -0.3230 2.75e-12
REACTOME INNATE IMMUNE SYSTEM 1002 2.26e-13 -0.1370 3.37e-11
REACTOME M PHASE 398 2.37e-12 -0.2050 3.24e-10
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS 83 2.89e-11 -0.4220 3.64e-09
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE 118 5.57e-11 -0.3490 6.53e-09
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 229 2.63e-10 -0.2420 2.88e-08
REACTOME INFECTIOUS DISEASE 910 2.83e-10 -0.1230 2.91e-08
REACTOME MEMBRANE TRAFFICKING 603 4.54e-10 -0.1490 4.38e-08
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION 1356 6.87e-10 -0.0998 6.27e-08
REACTOME DNA REPAIR 321 2.86e-09 -0.1930 2.47e-07
REACTOME TRANSCRIPTIONAL REGULATION BY TP53 351 7.29e-09 -0.1800 5.99e-07
REACTOME VESICLE MEDIATED TRANSPORT 642 1.22e-08 -0.1320 9.58e-07
REACTOME ESR MEDIATED SIGNALING 210 1.53e-08 -0.2260 1.14e-06
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION 140 3.97e-08 -0.2690 2.83e-06
REACTOME RHO GTPASE EFFECTORS 305 4.28e-08 -0.1820 2.87e-06
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION 90 4.37e-08 -0.3340 2.87e-06
REACTOME CHROMATIN MODIFYING ENZYMES 252 5.70e-08 -0.1990 3.60e-06
REACTOME MITOTIC PROMETAPHASE 194 8.58e-08 -0.2230 5.22e-06
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP 104 1.06e-07 -0.3020 6.24e-06
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS 113 2.17e-07 -0.2820 1.23e-05
REACTOME METABOLISM OF RNA 675 2.39e-07 -0.1170 1.31e-05
REACTOME DEUBIQUITINATION 260 3.30e-07 -0.1840 1.75e-05
REACTOME PRE NOTCH EXPRESSION AND PROCESSING 112 5.25e-07 -0.2740 2.70e-05
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 679 5.70e-07 -0.1130 2.84e-05
REACTOME DISEASES OF PROGRAMMED CELL DEATH 96 6.49e-07 -0.2940 3.13e-05
REACTOME SIGNALING BY NUCLEAR RECEPTORS 283 6.83e-07 -0.1720 3.13e-05
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS 188 6.85e-07 -0.2100 3.13e-05
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION 138 8.49e-07 -0.2430 3.77e-05
REACTOME HCMV INFECTION 152 9.47e-07 -0.2300 4.09e-05
REACTOME CELL CYCLE CHECKPOINTS 284 1.10e-06 -0.1680 4.65e-05
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES 66 1.16e-06 -0.3460 4.75e-05
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS 121 1.19e-06 -0.2560 4.77e-05
REACTOME HCMV EARLY EVENTS 128 1.66e-06 -0.2450 6.49e-05
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION 62 1.72e-06 -0.3510 6.57e-05
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION 84 1.85e-06 -0.3010 6.90e-05
REACTOME MEIOTIC RECOMBINATION 80 2.13e-06 -0.3070 7.77e-05
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 100 2.33e-06 -0.2730 8.31e-05
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 98 2.38e-06 -0.2760 8.33e-05
REACTOME PRC2 METHYLATES HISTONES AND DNA 65 2.98e-06 -0.3350 1.02e-04
REACTOME HDACS DEACETYLATE HISTONES 85 3.65e-06 -0.2900 1.22e-04
REACTOME ASPARAGINE N LINKED GLYCOSYLATION 299 3.73e-06 -0.1550 1.23e-04


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pANOVA s.dist p.adjustANOVA
REACTOME SENSORY PERCEPTION 555 7.47e-32 2.91e-01 1.23e-28
REACTOME OLFACTORY SIGNALING PATHWAY 348 1.02e-29 3.53e-01 8.34e-27
REACTOME KERATINIZATION 210 2.20e-21 3.80e-01 1.20e-18
REACTOME NEUTROPHIL DEGRANULATION 460 4.79e-21 -2.56e-01 1.96e-18
REACTOME CELLULAR RESPONSES TO STIMULI 779 6.41e-18 -1.82e-01 2.10e-15
REACTOME FORMATION OF THE CORNIFIED ENVELOPE 125 1.02e-17 4.44e-01 2.79e-15
REACTOME RNA POLYMERASE II TRANSCRIPTION 1336 7.46e-16 -1.31e-01 1.75e-13
REACTOME CELL CYCLE MITOTIC 539 1.97e-15 -2.00e-01 4.04e-13
REACTOME CELL CYCLE 666 2.24e-15 -1.80e-01 4.09e-13
REACTOME CELLULAR SENESCENCE 189 1.67e-14 -3.23e-01 2.75e-12
REACTOME INNATE IMMUNE SYSTEM 1002 2.26e-13 -1.37e-01 3.37e-11
REACTOME M PHASE 398 2.37e-12 -2.05e-01 3.24e-10
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS 83 2.89e-11 -4.22e-01 3.64e-09
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE 118 5.57e-11 -3.49e-01 6.53e-09
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 229 2.63e-10 -2.42e-01 2.88e-08
REACTOME INFECTIOUS DISEASE 910 2.83e-10 -1.23e-01 2.91e-08
REACTOME MEMBRANE TRAFFICKING 603 4.54e-10 -1.49e-01 4.38e-08
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION 1356 6.87e-10 -9.98e-02 6.27e-08
REACTOME DNA REPAIR 321 2.86e-09 -1.93e-01 2.47e-07
REACTOME TRANSCRIPTIONAL REGULATION BY TP53 351 7.29e-09 -1.80e-01 5.99e-07
REACTOME VESICLE MEDIATED TRANSPORT 642 1.22e-08 -1.32e-01 9.58e-07
REACTOME ESR MEDIATED SIGNALING 210 1.53e-08 -2.26e-01 1.14e-06
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION 140 3.97e-08 -2.69e-01 2.83e-06
REACTOME RHO GTPASE EFFECTORS 305 4.28e-08 -1.82e-01 2.87e-06
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION 90 4.37e-08 -3.34e-01 2.87e-06
REACTOME CHROMATIN MODIFYING ENZYMES 252 5.70e-08 -1.99e-01 3.60e-06
REACTOME MITOTIC PROMETAPHASE 194 8.58e-08 -2.23e-01 5.22e-06
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP 104 1.06e-07 -3.02e-01 6.24e-06
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS 113 2.17e-07 -2.82e-01 1.23e-05
REACTOME METABOLISM OF RNA 675 2.39e-07 -1.17e-01 1.31e-05
REACTOME DEUBIQUITINATION 260 3.30e-07 -1.84e-01 1.75e-05
REACTOME PRE NOTCH EXPRESSION AND PROCESSING 112 5.25e-07 -2.74e-01 2.70e-05
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 679 5.70e-07 -1.13e-01 2.84e-05
REACTOME DISEASES OF PROGRAMMED CELL DEATH 96 6.49e-07 -2.94e-01 3.13e-05
REACTOME SIGNALING BY NUCLEAR RECEPTORS 283 6.83e-07 -1.72e-01 3.13e-05
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS 188 6.85e-07 -2.10e-01 3.13e-05
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION 138 8.49e-07 -2.43e-01 3.77e-05
REACTOME HCMV INFECTION 152 9.47e-07 -2.30e-01 4.09e-05
REACTOME CELL CYCLE CHECKPOINTS 284 1.10e-06 -1.68e-01 4.65e-05
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES 66 1.16e-06 -3.46e-01 4.75e-05
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS 121 1.19e-06 -2.56e-01 4.77e-05
REACTOME HCMV EARLY EVENTS 128 1.66e-06 -2.45e-01 6.49e-05
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION 62 1.72e-06 -3.51e-01 6.57e-05
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION 84 1.85e-06 -3.01e-01 6.90e-05
REACTOME MEIOTIC RECOMBINATION 80 2.13e-06 -3.07e-01 7.77e-05
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 100 2.33e-06 -2.73e-01 8.31e-05
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 98 2.38e-06 -2.76e-01 8.33e-05
REACTOME PRC2 METHYLATES HISTONES AND DNA 65 2.98e-06 -3.35e-01 1.02e-04
REACTOME HDACS DEACETYLATE HISTONES 85 3.65e-06 -2.90e-01 1.22e-04
REACTOME ASPARAGINE N LINKED GLYCOSYLATION 299 3.73e-06 -1.55e-01 1.23e-04
REACTOME SIGNALING BY NOTCH 234 3.97e-06 -1.75e-01 1.26e-04
REACTOME MITOTIC PROPHASE 134 4.02e-06 -2.31e-01 1.26e-04
REACTOME DNA METHYLATION 58 4.07e-06 -3.50e-01 1.26e-04
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE 76 5.26e-06 -3.02e-01 1.59e-04
REACTOME HATS ACETYLATE HISTONES 129 5.33e-06 -2.32e-01 1.59e-04
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS 418 5.51e-06 -1.30e-01 1.62e-04
REACTOME EXTRACELLULAR MATRIX ORGANIZATION 291 5.85e-06 1.54e-01 1.69e-04
REACTOME MITOTIC G2 G2 M PHASES 194 6.16e-06 -1.88e-01 1.74e-04
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 59 6.26e-06 -3.40e-01 1.74e-04
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION 60 6.68e-06 -3.36e-01 1.83e-04
REACTOME RHO GTPASES ACTIVATE PKNS 86 9.99e-06 -2.76e-01 2.69e-04
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION 68 1.03e-05 -3.09e-01 2.73e-04
REACTOME ADAPTIVE IMMUNE SYSTEM 729 1.09e-05 -9.56e-02 2.84e-04
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION 183 1.18e-05 -1.88e-01 3.04e-04
REACTOME DNA REPLICATION 178 1.24e-05 -1.90e-01 3.14e-04
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES 91 1.35e-05 -2.64e-01 3.36e-04
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA 263 1.39e-05 -1.56e-01 3.41e-04
REACTOME RNA POLYMERASE I PROMOTER ESCAPE 83 1.69e-05 -2.73e-01 4.09e-04
REACTOME DNA REPLICATION PRE INITIATION 150 1.83e-05 -2.03e-01 4.35e-04
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE 277 1.86e-05 -1.49e-01 4.36e-04
REACTOME RNA POLYMERASE I TRANSCRIPTION 102 1.90e-05 -2.45e-01 4.40e-04
REACTOME UB SPECIFIC PROCESSING PROTEASES 187 2.13e-05 -1.80e-01 4.85e-04
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION 84 2.21e-05 -2.68e-01 4.97e-04
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT 159 2.61e-05 -1.93e-01 5.80e-04
REACTOME HCMV LATE EVENTS 110 3.01e-05 -2.30e-01 6.59e-04
REACTOME AURKA ACTIVATION BY TPX2 69 3.22e-05 -2.89e-01 6.96e-04
REACTOME ASPIRIN ADME 42 3.27e-05 3.70e-01 6.97e-04
REACTOME PROGRAMMED CELL DEATH 204 3.55e-05 -1.68e-01 7.46e-04
REACTOME HOMOLOGY DIRECTED REPAIR 132 4.03e-05 -2.07e-01 8.37e-04
REACTOME ONCOGENE INDUCED SENESCENCE 35 4.09e-05 -4.01e-01 8.40e-04
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES 78 4.87e-05 -2.66e-01 9.86e-04
REACTOME DNA DOUBLE STRAND BREAK REPAIR 162 4.93e-05 -1.85e-01 9.87e-04
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS 53 5.91e-05 -3.19e-01 1.17e-03
REACTOME MRNA SPLICING 197 6.38e-05 -1.65e-01 1.24e-03
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 688 6.43e-05 -8.94e-02 1.24e-03
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS 100 7.15e-05 -2.30e-01 1.37e-03
REACTOME SARS COV INFECTIONS 392 7.71e-05 -1.16e-01 1.45e-03
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING 67 8.71e-05 -2.77e-01 1.62e-03
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE 93 1.07e-04 -2.32e-01 1.98e-03
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT 236 1.09e-04 1.46e-01 1.98e-03
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT 152 1.14e-04 -1.81e-01 2.05e-03
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN 37 1.18e-04 -3.66e-01 2.11e-03
REACTOME PKMTS METHYLATE HISTONE LYSINES 64 1.46e-04 -2.75e-01 2.57e-03
REACTOME EICOSANOIDS 12 1.62e-04 6.29e-01 2.83e-03
REACTOME MUSCLE CONTRACTION 197 1.66e-04 1.56e-01 2.87e-03
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS 111 1.69e-04 -2.07e-01 2.88e-03
REACTOME MEIOSIS 110 1.70e-04 -2.07e-01 2.88e-03
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS 55 1.80e-04 2.92e-01 3.02e-03
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS 51 1.84e-04 -3.03e-01 3.04e-03
REACTOME G2 M DNA DAMAGE CHECKPOINT 90 1.86e-04 -2.28e-01 3.05e-03
REACTOME COLLAGEN CHAIN TRIMERIZATION 42 2.21e-04 3.29e-01 3.59e-03
REACTOME HDMS DEMETHYLATE HISTONES 40 2.29e-04 -3.37e-01 3.67e-03
REACTOME MITOTIC METAPHASE AND ANAPHASE 228 2.30e-04 -1.42e-01 3.67e-03
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC 198 2.36e-04 -1.52e-01 3.73e-03
REACTOME DEFENSINS 33 2.41e-04 3.69e-01 3.77e-03
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX 134 2.46e-04 1.83e-01 3.81e-03
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX 85 2.70e-04 -2.28e-01 4.15e-03
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS 93 3.08e-04 -2.16e-01 4.62e-03
REACTOME PROTEIN UBIQUITINATION 76 3.12e-04 -2.39e-01 4.62e-03
REACTOME SIGNALING BY ALK IN CANCER 53 3.12e-04 -2.86e-01 4.62e-03
REACTOME MITOCHONDRIAL PROTEIN IMPORT 58 3.12e-04 -2.74e-01 4.62e-03
REACTOME RESOLUTION OF SISTER CHROMATID COHESION 120 3.23e-04 -1.90e-01 4.74e-03
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE 66 3.31e-04 -2.55e-01 4.75e-03
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS 18 3.31e-04 -4.89e-01 4.75e-03
REACTOME CREATION OF C4 AND C2 ACTIVATORS 14 3.33e-04 5.54e-01 4.75e-03
REACTOME CILIUM ASSEMBLY 190 3.39e-04 -1.51e-01 4.80e-03
REACTOME PROTEIN LOCALIZATION 153 3.45e-04 -1.68e-01 4.80e-03
REACTOME SEPARATION OF SISTER CHROMATIDS 184 3.46e-04 -1.53e-01 4.80e-03
REACTOME SIGNALING BY INTERLEUKINS 444 3.48e-04 -9.90e-02 4.80e-03
REACTOME RESPIRATORY ELECTRON TRANSPORT 90 3.87e-04 -2.16e-01 5.29e-03
REACTOME G2 M CHECKPOINTS 162 4.07e-04 -1.61e-01 5.52e-03
REACTOME GENE SILENCING BY RNA 133 4.25e-04 -1.77e-01 5.73e-03
REACTOME SIGNALING BY FLT3 FUSION PROTEINS 19 4.56e-04 -4.64e-01 6.08e-03
REACTOME MHC CLASS II ANTIGEN PRESENTATION 121 4.70e-04 -1.84e-01 6.19e-03
REACTOME NONHOMOLOGOUS END JOINING NHEJ 64 4.71e-04 -2.53e-01 6.19e-03
REACTOME FLT3 SIGNALING IN DISEASE 28 4.80e-04 -3.81e-01 6.25e-03
REACTOME REGULATION OF TP53 ACTIVITY 156 4.89e-04 -1.62e-01 6.32e-03
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6 32 4.97e-04 -3.56e-01 6.35e-03
REACTOME KEAP1 NFE2L2 PATHWAY 104 4.99e-04 -1.98e-01 6.35e-03
REACTOME SIGNALING BY NTRKS 132 5.19e-04 -1.75e-01 6.55e-03
REACTOME COLLAGEN FORMATION 88 5.34e-04 2.14e-01 6.70e-03
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES 65 5.46e-04 2.48e-01 6.79e-03
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE 63 5.58e-04 -2.51e-01 6.89e-03
REACTOME AMYLOID FIBER FORMATION 102 6.06e-04 -1.96e-01 7.42e-03
REACTOME CHROMOSOME MAINTENANCE 130 6.19e-04 -1.74e-01 7.53e-03
REACTOME ECM PROTEOGLYCANS 73 6.45e-04 2.31e-01 7.74e-03
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS 139 6.46e-04 -1.68e-01 7.74e-03
REACTOME SIGNALING BY WNT 318 6.71e-04 -1.11e-01 7.98e-03
REACTOME INTERLEUKIN 36 PATHWAY 7 6.99e-04 7.40e-01 8.26e-03
REACTOME DRUG ADME 103 8.01e-04 1.91e-01 9.39e-03
REACTOME DIGESTION AND ABSORPTION 22 8.09e-04 4.13e-01 9.40e-03
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS 17 8.13e-04 -4.69e-01 9.40e-03
REACTOME FATTY ACIDS 15 8.19e-04 4.99e-01 9.40e-03
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS 16 8.49e-04 -4.82e-01 9.66e-03
REACTOME HEMOSTASIS 591 8.53e-04 -8.03e-02 9.66e-03
REACTOME PTEN REGULATION 135 8.74e-04 -1.66e-01 9.83e-03
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE 52 8.84e-04 -2.67e-01 9.87e-03
REACTOME SIGNALING BY ERYTHROPOIETIN 25 9.11e-04 -3.83e-01 1.01e-02
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION 361 9.57e-04 -1.01e-01 1.05e-02
REACTOME COPII MEDIATED VESICLE TRANSPORT 66 1.02e-03 -2.34e-01 1.11e-02
REACTOME BETA DEFENSINS 27 1.02e-03 3.65e-01 1.11e-02
REACTOME DIGESTION 17 1.08e-03 4.58e-01 1.16e-02
REACTOME SIGNALING BY PDGFR IN DISEASE 20 1.08e-03 -4.22e-01 1.16e-02
REACTOME VITAMIN C ASCORBATE METABOLISM 8 1.10e-03 -6.66e-01 1.17e-02
REACTOME TELOMERE MAINTENANCE 106 1.13e-03 -1.83e-01 1.19e-02
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS 82 1.16e-03 2.07e-01 1.22e-02
REACTOME RHO GTPASES ACTIVATE FORMINS 136 1.18e-03 -1.61e-01 1.23e-02
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 17 1.20e-03 4.54e-01 1.25e-02
REACTOME REGULATED NECROSIS 57 1.22e-03 -2.48e-01 1.25e-02
REACTOME RAB REGULATION OF TRAFFICKING 110 1.22e-03 -1.78e-01 1.25e-02
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES 59 1.24e-03 2.43e-01 1.27e-02
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF 53 1.26e-03 -2.56e-01 1.27e-02
REACTOME METABOLISM OF LIPIDS 709 1.26e-03 -7.11e-02 1.27e-02
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4 14 1.29e-03 4.97e-01 1.29e-02
REACTOME NCAM1 INTERACTIONS 41 1.31e-03 2.90e-01 1.30e-02
REACTOME APOPTOSIS 173 1.31e-03 -1.42e-01 1.30e-02
REACTOME TRANSPORT OF SMALL MOLECULES 697 1.34e-03 7.13e-02 1.31e-02
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT 101 1.34e-03 -1.85e-01 1.31e-02
REACTOME BASE EXCISION REPAIR AP SITE FORMATION 59 1.35e-03 -2.41e-01 1.31e-02
REACTOME GOLGI TO ER RETROGRADE TRANSPORT 132 1.36e-03 -1.61e-01 1.31e-02
REACTOME NEDDYLATION 235 1.37e-03 -1.21e-01 1.31e-02
REACTOME NUCLEOTIDE EXCISION REPAIR 107 1.38e-03 -1.79e-01 1.31e-02
REACTOME INTERLEUKIN 7 SIGNALING 31 1.42e-03 -3.31e-01 1.34e-02
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS 66 1.42e-03 2.27e-01 1.34e-02
REACTOME TP53 REGULATES METABOLIC GENES 81 1.44e-03 -2.05e-01 1.36e-02
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION 145 1.49e-03 -1.53e-01 1.39e-02
REACTOME DISEASES OF MITOTIC CELL CYCLE 37 1.62e-03 -2.99e-01 1.51e-02
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER 81 1.71e-03 -2.02e-01 1.58e-02
REACTOME BASE EXCISION REPAIR 87 1.75e-03 -1.94e-01 1.60e-02
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING 45 1.77e-03 -2.69e-01 1.61e-02
REACTOME MAPK1 ERK2 ACTIVATION 9 1.85e-03 -5.99e-01 1.67e-02
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND 55 1.86e-03 -2.43e-01 1.67e-02
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS 58 1.87e-03 -2.36e-01 1.67e-02
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING 127 1.88e-03 -1.60e-01 1.68e-02
REACTOME POTASSIUM CHANNELS 102 1.90e-03 1.78e-01 1.69e-02
REACTOME RHO GTPASES ACTIVATE IQGAPS 31 1.93e-03 -3.22e-01 1.70e-02
REACTOME PLASMA LIPOPROTEIN REMODELING 33 1.98e-03 3.11e-01 1.74e-02
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1 46 2.05e-03 -2.63e-01 1.79e-02
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES 39 2.15e-03 -2.84e-01 1.87e-02
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 98 2.21e-03 -1.79e-01 1.90e-02
REACTOME PI METABOLISM 79 2.22e-03 -1.99e-01 1.90e-02
REACTOME MITOCHONDRIAL TRANSLATION 93 2.26e-03 -1.83e-01 1.94e-02
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION 59 2.38e-03 -2.29e-01 2.02e-02
REACTOME S PHASE 159 2.39e-03 -1.40e-01 2.02e-02
REACTOME ERYTHROPOIETIN ACTIVATES RAS 14 2.51e-03 -4.66e-01 2.12e-02
REACTOME POTENTIAL THERAPEUTICS FOR SARS 92 2.55e-03 -1.82e-01 2.14e-02
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS 46 2.61e-03 2.56e-01 2.17e-02
REACTOME MYD88 INDEPENDENT TLR4 CASCADE 103 2.61e-03 -1.72e-01 2.17e-02
REACTOME PROTEIN FOLDING 96 2.71e-03 -1.77e-01 2.23e-02
REACTOME LYSOSOME VESICLE BIOGENESIS 33 2.76e-03 -3.01e-01 2.25e-02
REACTOME NEURONAL SYSTEM 388 2.76e-03 8.85e-02 2.25e-02
REACTOME RMTS METHYLATE HISTONE ARGININES 72 2.77e-03 -2.04e-01 2.25e-02
REACTOME SUMOYLATION 179 2.81e-03 -1.29e-01 2.28e-02
REACTOME NOD1 2 SIGNALING PATHWAY 33 2.89e-03 -3.00e-01 2.33e-02
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE 100 2.96e-03 -1.72e-01 2.37e-02
REACTOME DNA DOUBLE STRAND BREAK RESPONSE 74 3.07e-03 -1.99e-01 2.45e-02
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION 26 3.12e-03 -3.35e-01 2.47e-02
REACTOME INFLAMMASOMES 21 3.22e-03 -3.71e-01 2.54e-02
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX 41 3.25e-03 -2.66e-01 2.55e-02
REACTOME MITOTIC SPINDLE CHECKPOINT 109 3.28e-03 -1.63e-01 2.56e-02
REACTOME THE NLRP3 INFLAMMASOME 16 3.29e-03 -4.24e-01 2.56e-02
REACTOME METALLOPROTEASE DUBS 36 3.32e-03 -2.83e-01 2.57e-02
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES 7 3.36e-03 -6.40e-01 2.59e-02
REACTOME CLEC7A DECTIN 1 SIGNALING 97 3.44e-03 -1.72e-01 2.64e-02
REACTOME REPRODUCTION 136 3.55e-03 -1.45e-01 2.71e-02
REACTOME STRIATED MUSCLE CONTRACTION 35 3.67e-03 2.84e-01 2.79e-02
REACTOME COLLAGEN DEGRADATION 61 3.69e-03 2.15e-01 2.79e-02
REACTOME SARS COV 1 INFECTION 136 3.73e-03 -1.44e-01 2.80e-02
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR 66 3.73e-03 -2.06e-01 2.80e-02
REACTOME PD 1 SIGNALING 21 3.80e-03 3.65e-01 2.84e-02
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS 30 3.93e-03 3.04e-01 2.92e-02
REACTOME ANCHORING FIBRIL FORMATION 13 4.01e-03 4.61e-01 2.97e-02
REACTOME ORGANIC ANION TRANSPORT 5 4.05e-03 7.42e-01 2.98e-02
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY 17 4.18e-03 -4.01e-01 3.06e-02
REACTOME SIGNALING BY VEGF 102 4.20e-03 -1.64e-01 3.06e-02
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION 22 4.25e-03 -3.52e-01 3.09e-02
REACTOME ANTIMICROBIAL PEPTIDES 76 4.29e-03 1.89e-01 3.10e-02
REACTOME CYTOPROTECTION BY HMOX1 59 4.36e-03 -2.15e-01 3.14e-02
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION 36 4.39e-03 -2.74e-01 3.15e-02
REACTOME NUCLEOTIDE SALVAGE 21 4.46e-03 -3.58e-01 3.17e-02
REACTOME INTRAFLAGELLAR TRANSPORT 50 4.46e-03 -2.32e-01 3.17e-02
REACTOME SENSORY PROCESSING OF SOUND 72 4.64e-03 1.93e-01 3.28e-02
REACTOME SHC1 EVENTS IN EGFR SIGNALING 14 4.72e-03 -4.36e-01 3.33e-02
REACTOME INITIAL TRIGGERING OF COMPLEMENT 21 4.76e-03 3.56e-01 3.34e-02
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT 222 4.92e-03 -1.10e-01 3.42e-02
REACTOME TNF SIGNALING 54 4.92e-03 -2.21e-01 3.42e-02
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS 18 5.34e-03 3.79e-01 3.70e-02
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE 71 5.46e-03 -1.91e-01 3.77e-02
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2 77 5.58e-03 -1.83e-01 3.83e-02
REACTOME SIGNALING BY HEDGEHOG 148 5.62e-03 -1.32e-01 3.84e-02
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER 76 5.72e-03 -1.83e-01 3.89e-02
REACTOME SIGNALING BY EGFR IN CANCER 25 5.74e-03 -3.19e-01 3.89e-02
REACTOME INTERLEUKIN 17 SIGNALING 66 5.77e-03 -1.96e-01 3.90e-02
REACTOME SIGNALING BY CSF3 G CSF 30 5.88e-03 -2.91e-01 3.95e-02
REACTOME INTERLEUKIN 6 SIGNALING 11 5.90e-03 -4.79e-01 3.95e-02
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION 11 5.98e-03 -4.79e-01 3.99e-02
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES 34 6.17e-03 -2.71e-01 4.10e-02
REACTOME NGF STIMULATED TRANSCRIPTION 38 6.19e-03 -2.57e-01 4.10e-02
REACTOME CARDIAC CONDUCTION 125 6.23e-03 1.42e-01 4.11e-02
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES 507 6.35e-03 -7.08e-02 4.17e-02
REACTOME SENSORY PERCEPTION OF TASTE 47 6.57e-03 2.29e-01 4.28e-02
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION 12 6.57e-03 4.53e-01 4.28e-02
REACTOME SIGNALING BY ERBB2 50 6.69e-03 -2.22e-01 4.34e-02
REACTOME AUTOPHAGY 144 6.80e-03 -1.31e-01 4.40e-02
REACTOME HIV INFECTION 223 7.05e-03 -1.05e-01 4.52e-02
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY 84 7.08e-03 -1.70e-01 4.52e-02
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS 9 7.09e-03 -5.18e-01 4.52e-02
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES 18 7.10e-03 3.66e-01 4.52e-02
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS 299 7.14e-03 -9.04e-02 4.53e-02
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS 10 7.25e-03 -4.90e-01 4.58e-02
REACTOME GPCR LIGAND BINDING 444 7.51e-03 7.40e-02 4.71e-02
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY 23 7.51e-03 -3.22e-01 4.71e-02
REACTOME DNA DAMAGE RECOGNITION IN GG NER 36 7.85e-03 -2.56e-01 4.90e-02
REACTOME UNFOLDED PROTEIN RESPONSE UPR 88 8.11e-03 -1.63e-01 5.04e-02
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE 17 8.27e-03 3.70e-01 5.13e-02
REACTOME IRE1ALPHA ACTIVATES CHAPERONES 48 8.32e-03 -2.20e-01 5.14e-02
REACTOME MET ACTIVATES PTK2 SIGNALING 30 8.47e-03 2.78e-01 5.21e-02
REACTOME C TYPE LECTIN RECEPTORS CLRS 136 8.52e-03 -1.31e-01 5.22e-02
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH 62 8.63e-03 1.93e-01 5.25e-02
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING 11 8.64e-03 4.57e-01 5.25e-02
REACTOME ERYTHROPOIETIN ACTIVATES STAT5 7 8.86e-03 -5.71e-01 5.37e-02
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS 83 9.11e-03 -1.66e-01 5.49e-02
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2 60 9.13e-03 -1.95e-01 5.49e-02
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR 106 9.24e-03 -1.46e-01 5.54e-02
REACTOME HIV LIFE CYCLE 145 9.68e-03 -1.24e-01 5.78e-02
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS 100 9.97e-03 -1.49e-01 5.93e-02
REACTOME INTEGRIN CELL SURFACE INTERACTIONS 83 1.00e-02 1.63e-01 5.95e-02
REACTOME LAMININ INTERACTIONS 28 1.04e-02 2.80e-01 6.13e-02
REACTOME LEISHMANIA INFECTION 156 1.04e-02 -1.19e-01 6.14e-02
REACTOME RESOLUTION OF D LOOP STRUCTURES 33 1.05e-02 -2.57e-01 6.15e-02
REACTOME CGMP EFFECTS 16 1.06e-02 3.69e-01 6.16e-02
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP 41 1.06e-02 -2.31e-01 6.16e-02
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE 48 1.06e-02 -2.13e-01 6.16e-02
REACTOME METABOLISM OF COFACTORS 19 1.07e-02 -3.38e-01 6.18e-02
REACTOME TRANSLATION 278 1.08e-02 -8.88e-02 6.21e-02
REACTOME EICOSANOID LIGAND BINDING RECEPTORS 14 1.09e-02 -3.93e-01 6.23e-02
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING 32 1.11e-02 -2.59e-01 6.35e-02
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY 41 1.11e-02 -2.29e-01 6.35e-02
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL 19 1.13e-02 3.35e-01 6.43e-02
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX 51 1.14e-02 -2.05e-01 6.43e-02
REACTOME SIGNALING BY GPCR 673 1.15e-02 5.71e-02 6.49e-02
REACTOME INTERLEUKIN 2 FAMILY SIGNALING 40 1.16e-02 -2.31e-01 6.51e-02
REACTOME SARS COV 2 HOST INTERACTIONS 191 1.17e-02 -1.06e-01 6.57e-02
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES 34 1.23e-02 -2.48e-01 6.88e-02
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS 68 1.24e-02 -1.75e-01 6.90e-02
REACTOME MISCELLANEOUS SUBSTRATES 12 1.24e-02 4.17e-01 6.90e-02
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES 49 1.25e-02 -2.06e-01 6.90e-02
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION 20 1.25e-02 -3.22e-01 6.91e-02
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC 28 1.27e-02 -2.72e-01 6.96e-02
REACTOME GENERATION OF SECOND MESSENGER MOLECULES 30 1.27e-02 2.63e-01 6.96e-02
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE 20 1.28e-02 -3.21e-01 7.01e-02
REACTOME DEFECTIVE F9 ACTIVATION 5 1.30e-02 -6.42e-01 7.06e-02
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION 15 1.31e-02 3.70e-01 7.09e-02
REACTOME TBC RABGAPS 40 1.32e-02 -2.27e-01 7.11e-02
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER 18 1.32e-02 -3.37e-01 7.12e-02
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2 12 1.36e-02 4.12e-01 7.28e-02
REACTOME SARS COV 2 INFECTION 281 1.39e-02 -8.53e-02 7.42e-02
REACTOME MAPK FAMILY SIGNALING CASCADES 314 1.41e-02 -8.06e-02 7.51e-02
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS 11 1.41e-02 -4.27e-01 7.51e-02
REACTOME INTERLEUKIN 21 SIGNALING 9 1.42e-02 -4.72e-01 7.51e-02
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION 11 1.43e-02 4.27e-01 7.53e-02
REACTOME VISUAL PHOTOTRANSDUCTION 93 1.44e-02 1.47e-01 7.56e-02
REACTOME FLT3 SIGNALING 38 1.44e-02 -2.29e-01 7.56e-02
REACTOME CD209 DC SIGN SIGNALING 20 1.46e-02 -3.16e-01 7.58e-02
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY 30 1.46e-02 -2.58e-01 7.58e-02
REACTOME PI5P REGULATES TP53 ACETYLATION 9 1.46e-02 -4.70e-01 7.58e-02
REACTOME IRON UPTAKE AND TRANSPORT 56 1.46e-02 -1.89e-01 7.58e-02
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS 13 1.51e-02 -3.89e-01 7.80e-02
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION 296 1.52e-02 -8.20e-02 7.80e-02
REACTOME PHOSPHOLIPID METABOLISM 201 1.52e-02 -9.93e-02 7.80e-02
REACTOME STAT5 ACTIVATION 7 1.53e-02 -5.30e-01 7.80e-02
REACTOME CARGO CONCENTRATION IN THE ER 32 1.54e-02 -2.48e-01 7.82e-02
REACTOME UBIQUINOL BIOSYNTHESIS 8 1.54e-02 -4.95e-01 7.82e-02
REACTOME SELECTIVE AUTOPHAGY 79 1.55e-02 -1.57e-01 7.86e-02
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI 17 1.56e-02 -3.39e-01 7.86e-02
REACTOME OPSINS 7 1.56e-02 5.28e-01 7.86e-02
REACTOME TOLL LIKE RECEPTOR CASCADES 158 1.57e-02 -1.11e-01 7.86e-02
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION 59 1.57e-02 -1.82e-01 7.86e-02
REACTOME AMINO ACID CONJUGATION 9 1.58e-02 4.65e-01 7.86e-02
REACTOME SIGNALING BY NOTCH1 69 1.58e-02 -1.68e-01 7.86e-02
REACTOME DEATH RECEPTOR SIGNALING 143 1.63e-02 -1.16e-01 8.07e-02
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS 38 1.63e-02 2.25e-01 8.08e-02
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION 160 1.68e-02 -1.10e-01 8.26e-02
REACTOME INTERLEUKIN 1 SIGNALING 110 1.68e-02 -1.32e-01 8.26e-02
REACTOME RECYCLING PATHWAY OF L1 43 1.69e-02 -2.11e-01 8.26e-02
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS 118 1.69e-02 1.27e-01 8.26e-02
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION 29 1.71e-02 -2.56e-01 8.32e-02
REACTOME SIGNALING BY EGFR 49 1.72e-02 -1.97e-01 8.37e-02
REACTOME HYDROLYSIS OF LPC 9 1.74e-02 4.58e-01 8.43e-02
REACTOME ATORVASTATIN ADME 9 1.75e-02 4.57e-01 8.47e-02
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES 11 1.77e-02 -4.13e-01 8.50e-02
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS 5 1.77e-02 6.12e-01 8.50e-02
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA 52 1.80e-02 1.90e-01 8.59e-02
REACTOME RAC2 GTPASE CYCLE 81 1.80e-02 -1.52e-01 8.59e-02
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE 109 1.81e-02 -1.31e-01 8.60e-02
REACTOME G1 S SPECIFIC TRANSCRIPTION 28 1.83e-02 -2.58e-01 8.68e-02
REACTOME RIPK1 MEDIATED REGULATED NECROSIS 30 1.86e-02 -2.48e-01 8.78e-02
REACTOME SARS COV 2 MODULATES AUTOPHAGY 11 1.93e-02 -4.08e-01 9.09e-02
REACTOME TIE2 SIGNALING 18 1.95e-02 -3.18e-01 9.13e-02
REACTOME SIGNALING BY LEPTIN 11 1.95e-02 -4.07e-01 9.13e-02
REACTOME PROSTANOID LIGAND RECEPTORS 9 1.98e-02 -4.49e-01 9.22e-02
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB 5 1.98e-02 -6.02e-01 9.22e-02
REACTOME MEIOTIC SYNAPSIS 73 1.99e-02 -1.58e-01 9.24e-02
REACTOME N GLYCAN ANTENNAE ELONGATION 15 2.00e-02 -3.47e-01 9.29e-02
REACTOME MITOCHONDRIAL BIOGENESIS 87 2.02e-02 -1.44e-01 9.35e-02
REACTOME SIGNALING BY NOTCH4 80 2.03e-02 -1.50e-01 9.37e-02
REACTOME METABOLISM OF NUCLEOTIDES 94 2.08e-02 -1.38e-01 9.56e-02
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES 38 2.09e-02 2.17e-01 9.56e-02
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION 250 2.09e-02 -8.48e-02 9.56e-02
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS 81 2.11e-02 -1.48e-01 9.63e-02
REACTOME MAPK3 ERK1 ACTIVATION 10 2.14e-02 -4.20e-01 9.71e-02
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES 43 2.17e-02 -2.02e-01 9.83e-02
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE 6 2.17e-02 5.41e-01 9.83e-02
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC 26 2.18e-02 -2.60e-01 9.85e-02
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION 19 2.20e-02 3.03e-01 9.92e-02
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION 13 2.22e-02 -3.66e-01 9.93e-02
REACTOME UCH PROTEINASES 99 2.22e-02 -1.33e-01 9.93e-02
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND 16 2.23e-02 -3.30e-01 9.97e-02
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES 12 2.25e-02 -3.80e-01 1.00e-01
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER 54 2.26e-02 -1.79e-01 1.00e-01
REACTOME COMPLEX I BIOGENESIS 49 2.27e-02 -1.88e-01 1.00e-01
REACTOME HEDGEHOG OFF STATE 111 2.30e-02 -1.25e-01 1.01e-01
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 44 2.31e-02 -1.98e-01 1.01e-01
REACTOME PHASE 0 RAPID DEPOLARISATION 31 2.31e-02 2.36e-01 1.01e-01
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION 7 2.32e-02 4.96e-01 1.01e-01
REACTOME PREDNISONE ADME 10 2.33e-02 4.14e-01 1.01e-01
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE 15 2.33e-02 -3.38e-01 1.01e-01
REACTOME CHYLOMICRON REMODELING 10 2.33e-02 4.14e-01 1.01e-01
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS 52 2.35e-02 -1.82e-01 1.02e-01
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE 63 2.38e-02 1.65e-01 1.03e-01
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS 24 2.40e-02 -2.66e-01 1.03e-01
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES 77 2.40e-02 -1.49e-01 1.03e-01
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS 86 2.41e-02 -1.41e-01 1.03e-01
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION 8 2.43e-02 4.60e-01 1.04e-01
REACTOME RHOV GTPASE CYCLE 36 2.43e-02 -2.17e-01 1.04e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE 35 2.45e-02 -2.20e-01 1.04e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION 41 2.45e-02 -2.03e-01 1.04e-01
REACTOME RAC3 GTPASE CYCLE 85 2.46e-02 -1.41e-01 1.04e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS 9 2.47e-02 -4.32e-01 1.04e-01
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS 12 2.48e-02 -3.74e-01 1.05e-01
REACTOME G0 AND EARLY G1 27 2.51e-02 -2.49e-01 1.05e-01
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE 10 2.52e-02 4.09e-01 1.06e-01
REACTOME PYRIMIDINE SALVAGE 10 2.53e-02 -4.08e-01 1.06e-01
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION 19 2.54e-02 -2.96e-01 1.06e-01
REACTOME PREGNENOLONE BIOSYNTHESIS 12 2.57e-02 -3.72e-01 1.07e-01
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS 101 2.57e-02 1.28e-01 1.07e-01
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS 16 2.61e-02 3.21e-01 1.08e-01
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES 55 2.63e-02 1.73e-01 1.09e-01
REACTOME PYROPTOSIS 27 2.68e-02 -2.46e-01 1.10e-01
REACTOME VASOPRESSIN LIKE RECEPTORS 5 2.70e-02 -5.71e-01 1.11e-01
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS 15 2.71e-02 -3.30e-01 1.11e-01
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE 43 2.72e-02 -1.95e-01 1.11e-01
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING 24 2.78e-02 -2.59e-01 1.13e-01
REACTOME ONCOGENIC MAPK SIGNALING 79 2.78e-02 -1.43e-01 1.13e-01
REACTOME AMINO ACIDS REGULATE MTORC1 53 2.81e-02 -1.74e-01 1.14e-01
REACTOME HS GAG BIOSYNTHESIS 28 2.83e-02 2.39e-01 1.14e-01
REACTOME REGULATION OF PTEN MRNA TRANSLATION 9 2.85e-02 -4.22e-01 1.15e-01
REACTOME PROTEIN REPAIR 6 2.87e-02 -5.16e-01 1.15e-01
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 52 2.88e-02 -1.75e-01 1.16e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION 89 2.91e-02 -1.34e-01 1.16e-01
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS 54 2.91e-02 -1.72e-01 1.16e-01
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE 17 2.94e-02 -3.05e-01 1.17e-01
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR 79 2.96e-02 -1.42e-01 1.18e-01
REACTOME GLUCOCORTICOID BIOSYNTHESIS 10 2.98e-02 3.97e-01 1.18e-01
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY 25 3.01e-02 -2.51e-01 1.19e-01
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION 12 3.03e-02 3.61e-01 1.19e-01
REACTOME DAP12 INTERACTIONS 37 3.06e-02 -2.05e-01 1.20e-01
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES 30 3.07e-02 2.28e-01 1.20e-01
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH 9 3.07e-02 -4.16e-01 1.20e-01
REACTOME FIBRONECTIN MATRIX FORMATION 6 3.08e-02 -5.09e-01 1.20e-01
REACTOME EGFR DOWNREGULATION 30 3.09e-02 -2.28e-01 1.21e-01
REACTOME CLEC7A INFLAMMASOME PATHWAY 6 3.10e-02 -5.08e-01 1.21e-01
REACTOME PENTOSE PHOSPHATE PATHWAY 12 3.16e-02 -3.58e-01 1.23e-01
REACTOME PEPTIDE LIGAND BINDING RECEPTORS 188 3.19e-02 9.07e-02 1.23e-01
REACTOME MET PROMOTES CELL MOTILITY 41 3.21e-02 1.93e-01 1.24e-01
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION 16 3.21e-02 -3.09e-01 1.24e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI 26 3.22e-02 -2.43e-01 1.24e-01
REACTOME SIGNALING BY SCF KIT 42 3.28e-02 -1.90e-01 1.26e-01
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR 7 3.31e-02 -4.65e-01 1.27e-01
REACTOME INTERLEUKIN 6 FAMILY SIGNALING 24 3.41e-02 -2.50e-01 1.30e-01
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS 43 3.42e-02 -1.87e-01 1.30e-01
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS 12 3.46e-02 -3.52e-01 1.31e-01
REACTOME INTERLEUKIN 15 SIGNALING 13 3.47e-02 -3.38e-01 1.32e-01
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES 21 3.48e-02 2.66e-01 1.32e-01
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS 23 3.52e-02 2.54e-01 1.33e-01
REACTOME O LINKED GLYCOSYLATION 109 3.53e-02 1.17e-01 1.33e-01
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING 74 3.56e-02 -1.41e-01 1.34e-01
REACTOME SYNTHESIS OF DNA 119 3.57e-02 -1.11e-01 1.34e-01
REACTOME SIGNALING BY KIT IN DISEASE 20 3.57e-02 -2.71e-01 1.34e-01
REACTOME CIRCADIAN CLOCK 68 3.59e-02 -1.47e-01 1.34e-01
REACTOME INSULIN RECEPTOR RECYCLING 29 3.61e-02 -2.25e-01 1.34e-01
REACTOME DISEASES OF GLYCOSYLATION 137 3.61e-02 1.04e-01 1.34e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX 19 3.64e-02 -2.77e-01 1.35e-01
REACTOME SYNDECAN INTERACTIONS 26 3.65e-02 2.37e-01 1.35e-01
REACTOME DEADENYLATION DEPENDENT MRNA DECAY 56 3.70e-02 -1.61e-01 1.37e-01
REACTOME CALCINEURIN ACTIVATES NFAT 9 3.73e-02 -4.01e-01 1.37e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K 12 3.76e-02 -3.47e-01 1.38e-01
REACTOME DISEASES OF DNA REPAIR 51 3.76e-02 -1.68e-01 1.38e-01
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS 12 3.78e-02 3.46e-01 1.38e-01
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION 14 3.90e-02 -3.19e-01 1.42e-01
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION 29 3.92e-02 -2.21e-01 1.42e-01
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS 39 3.92e-02 1.91e-01 1.42e-01
REACTOME METABOLISM OF FOLATE AND PTERINES 17 4.13e-02 -2.86e-01 1.50e-01
REACTOME SIGNALING BY PTK6 54 4.14e-02 -1.60e-01 1.50e-01
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS 37 4.23e-02 -1.93e-01 1.53e-01
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT 77 4.28e-02 -1.33e-01 1.54e-01
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES 9 4.29e-02 3.90e-01 1.54e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 11 4.31e-02 -3.52e-01 1.55e-01
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF 17 4.41e-02 -2.82e-01 1.57e-01
REACTOME MET ACTIVATES RAS SIGNALING 11 4.41e-02 -3.51e-01 1.57e-01
REACTOME GLUCURONIDATION 23 4.48e-02 2.42e-01 1.59e-01
REACTOME SIGNALING BY MAPK MUTANTS 6 4.48e-02 -4.73e-01 1.59e-01
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 22 4.48e-02 -2.47e-01 1.59e-01
REACTOME AGGREPHAGY 42 4.51e-02 -1.79e-01 1.60e-01
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS 74 4.54e-02 -1.35e-01 1.60e-01
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING 13 4.54e-02 3.20e-01 1.60e-01
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES 118 4.60e-02 -1.06e-01 1.62e-01
REACTOME PROTEIN METHYLATION 17 4.69e-02 -2.78e-01 1.64e-01
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS 5 4.70e-02 -5.13e-01 1.64e-01
REACTOME DIGESTION OF DIETARY CARBOHYDRATE 6 4.70e-02 4.68e-01 1.64e-01
REACTOME RHOBTB GTPASE CYCLE 34 4.73e-02 -1.97e-01 1.65e-01
REACTOME G1 S DNA DAMAGE CHECKPOINTS 67 4.75e-02 -1.40e-01 1.65e-01
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING 25 4.81e-02 -2.28e-01 1.67e-01
REACTOME ABACAVIR ADME 9 4.82e-02 3.80e-01 1.67e-01
REACTOME INWARDLY RECTIFYING K CHANNELS 35 4.83e-02 1.93e-01 1.67e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST 18 4.85e-02 -2.69e-01 1.67e-01
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM 20 4.89e-02 -2.54e-01 1.68e-01
REACTOME ATTACHMENT AND ENTRY 16 4.93e-02 2.84e-01 1.69e-01
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING 23 5.00e-02 -2.36e-01 1.71e-01
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA 8 5.01e-02 -4.00e-01 1.71e-01
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING 26 5.01e-02 -2.22e-01 1.71e-01
REACTOME INTERFERON SIGNALING 193 5.01e-02 -8.18e-02 1.71e-01
REACTOME MRNA SPLICING MINOR PATHWAY 49 5.04e-02 -1.62e-01 1.71e-01
REACTOME METABOLISM OF STEROIDS 150 5.15e-02 -9.21e-02 1.75e-01
REACTOME RAB GERANYLGERANYLATION 57 5.18e-02 -1.49e-01 1.75e-01
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING 34 5.21e-02 -1.92e-01 1.76e-01
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B 7 5.22e-02 -4.24e-01 1.76e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS 32 5.23e-02 -1.98e-01 1.76e-01
REACTOME DEFECTIVE GALNT3 CAUSES HFTC 16 5.24e-02 2.80e-01 1.76e-01
REACTOME CALNEXIN CALRETICULIN CYCLE 26 5.25e-02 -2.20e-01 1.76e-01
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS 55 5.28e-02 -1.51e-01 1.76e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING 30 5.28e-02 -2.04e-01 1.76e-01
REACTOME SUMOYLATION OF RNA BINDING PROTEINS 47 5.30e-02 -1.63e-01 1.76e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES 11 5.30e-02 -3.37e-01 1.76e-01
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA 77 5.37e-02 -1.27e-01 1.78e-01
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE 91 5.39e-02 -1.17e-01 1.78e-01
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION 32 5.40e-02 1.97e-01 1.79e-01
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION 15 5.44e-02 -2.87e-01 1.79e-01
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING 14 5.50e-02 -2.96e-01 1.81e-01
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA 115 5.51e-02 -1.04e-01 1.81e-01
REACTOME RUNX3 REGULATES P14 ARF 10 5.52e-02 -3.50e-01 1.81e-01
REACTOME INTERLEUKIN 20 FAMILY SIGNALING 25 5.55e-02 -2.21e-01 1.82e-01
REACTOME KINESINS 59 5.56e-02 -1.44e-01 1.82e-01
REACTOME RAF ACTIVATION 33 5.61e-02 -1.92e-01 1.83e-01
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE 9 5.63e-02 -3.67e-01 1.83e-01
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 19 5.66e-02 -2.53e-01 1.84e-01
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS 8 5.69e-02 3.89e-01 1.84e-01
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS 11 5.71e-02 3.31e-01 1.84e-01
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 11 5.75e-02 -3.31e-01 1.85e-01
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION 74 5.75e-02 -1.28e-01 1.85e-01
REACTOME MAPK6 MAPK4 SIGNALING 91 5.81e-02 -1.15e-01 1.86e-01
REACTOME SARS COV 1 HOST INTERACTIONS 92 5.81e-02 -1.14e-01 1.86e-01
REACTOME APOPTOTIC EXECUTION PHASE 49 5.83e-02 -1.56e-01 1.87e-01
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION 21 5.90e-02 2.38e-01 1.88e-01
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE 9 5.93e-02 3.63e-01 1.89e-01
REACTOME PI 3K CASCADE FGFR2 22 5.98e-02 2.32e-01 1.90e-01
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS 14 6.05e-02 2.90e-01 1.92e-01
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS 7 6.05e-02 -4.10e-01 1.92e-01
REACTOME PURINE SALVAGE 12 6.15e-02 -3.12e-01 1.94e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR 24 6.25e-02 -2.20e-01 1.97e-01
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX 14 6.26e-02 -2.87e-01 1.97e-01
REACTOME GLUTATHIONE CONJUGATION 33 6.28e-02 -1.87e-01 1.97e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA 27 6.40e-02 -2.06e-01 2.01e-01
REACTOME STIMULI SENSING CHANNELS 100 6.50e-02 1.07e-01 2.04e-01
REACTOME REGULATION OF BACH1 ACTIVITY 11 6.51e-02 -3.21e-01 2.04e-01
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY 5 6.58e-02 -4.75e-01 2.05e-01
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY 74 6.60e-02 -1.24e-01 2.06e-01
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS 14 6.62e-02 -2.84e-01 2.06e-01
REACTOME TRIGLYCERIDE METABOLISM 35 6.72e-02 1.79e-01 2.08e-01
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES 27 6.73e-02 -2.03e-01 2.08e-01
REACTOME ACYL CHAIN REMODELLING OF PI 17 6.73e-02 2.56e-01 2.08e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX 91 6.77e-02 -1.11e-01 2.09e-01
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS 7 6.78e-02 3.99e-01 2.09e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS 7 6.79e-02 -3.98e-01 2.09e-01
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES 21 6.80e-02 -2.30e-01 2.09e-01
REACTOME REGULATION OF SIGNALING BY CBL 22 6.81e-02 -2.25e-01 2.09e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING 5 6.84e-02 -4.71e-01 2.09e-01
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS 16 6.85e-02 -2.63e-01 2.09e-01
REACTOME SCAVENGING BY CLASS F RECEPTORS 6 6.86e-02 -4.29e-01 2.09e-01
REACTOME G ALPHA I SIGNALLING EVENTS 304 6.90e-02 6.06e-02 2.10e-01
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION 35 6.92e-02 -1.78e-01 2.10e-01
REACTOME INTERLEUKIN 12 SIGNALING 43 6.96e-02 -1.60e-01 2.11e-01
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES 6 7.09e-02 -4.26e-01 2.15e-01
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS 28 7.13e-02 -1.97e-01 2.15e-01
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY 26 7.14e-02 -2.04e-01 2.15e-01
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R 9 7.14e-02 -3.47e-01 2.15e-01
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 59 7.21e-02 -1.35e-01 2.16e-01
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III 31 7.22e-02 -1.87e-01 2.16e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION 19 7.26e-02 -2.38e-01 2.17e-01
REACTOME RHO GTPASES ACTIVATE KTN1 11 7.26e-02 -3.13e-01 2.17e-01
REACTOME RHO GTPASE CYCLE 423 7.31e-02 -5.08e-02 2.18e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K 7 7.34e-02 -3.91e-01 2.18e-01
REACTOME SIGNALING BY NOTCH2 32 7.38e-02 -1.83e-01 2.19e-01
REACTOME ASPARTATE AND ASPARAGINE METABOLISM 11 7.41e-02 -3.11e-01 2.20e-01
REACTOME DNA DAMAGE BYPASS 47 7.43e-02 -1.50e-01 2.20e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING 22 7.46e-02 -2.20e-01 2.20e-01
REACTOME FCERI MEDIATED NF KB ACTIVATION 78 7.47e-02 -1.17e-01 2.20e-01
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY 67 7.50e-02 -1.26e-01 2.21e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES 16 7.53e-02 -2.57e-01 2.21e-01
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS 20 7.56e-02 -2.29e-01 2.22e-01
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION 9 7.69e-02 -3.41e-01 2.25e-01
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING 33 7.71e-02 1.78e-01 2.25e-01
REACTOME SOS MEDIATED SIGNALLING 7 7.72e-02 -3.86e-01 2.25e-01
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS 30 7.80e-02 -1.86e-01 2.27e-01
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS 63 7.83e-02 -1.28e-01 2.28e-01
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING 5 7.85e-02 4.54e-01 2.28e-01
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX 15 7.86e-02 -2.62e-01 2.28e-01
REACTOME RUNX3 REGULATES WNT SIGNALING 8 7.89e-02 3.59e-01 2.28e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES 10 7.90e-02 -3.21e-01 2.28e-01
REACTOME PEXOPHAGY 11 7.92e-02 -3.06e-01 2.28e-01
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 7.93e-02 2.62e-01 2.28e-01
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY 6 7.94e-02 -4.14e-01 2.28e-01
REACTOME OVARIAN TUMOR DOMAIN PROTEASES 36 8.04e-02 -1.68e-01 2.30e-01
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS 25 8.05e-02 -2.02e-01 2.30e-01
REACTOME ROBO RECEPTORS BIND AKAP5 9 8.12e-02 -3.36e-01 2.32e-01
REACTOME METABOLISM OF CARBOHYDRATES 279 8.22e-02 -6.05e-02 2.34e-01
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS 312 8.23e-02 5.72e-02 2.34e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS 15 8.23e-02 -2.59e-01 2.34e-01
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA 37 8.25e-02 -1.65e-01 2.34e-01
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION 81 8.25e-02 -1.12e-01 2.34e-01
REACTOME REGULATED PROTEOLYSIS OF P75NTR 11 8.31e-02 -3.02e-01 2.35e-01
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE 52 8.33e-02 -1.39e-01 2.35e-01
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS 87 8.35e-02 -1.07e-01 2.35e-01
REACTOME SURFACTANT METABOLISM 28 8.36e-02 1.89e-01 2.35e-01
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES 28 8.36e-02 -1.89e-01 2.35e-01
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING 25 8.37e-02 2.00e-01 2.35e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS 15 8.44e-02 2.57e-01 2.36e-01
REACTOME RHOBTB2 GTPASE CYCLE 22 8.45e-02 -2.12e-01 2.36e-01
REACTOME PI 3K CASCADE FGFR4 19 8.47e-02 2.28e-01 2.36e-01
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY 72 8.48e-02 -1.17e-01 2.36e-01
REACTOME CRISTAE FORMATION 27 8.48e-02 -1.92e-01 2.36e-01
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY 5 8.52e-02 -4.45e-01 2.36e-01
REACTOME INTERLEUKIN 1 FAMILY SIGNALING 146 8.61e-02 -8.23e-02 2.38e-01
REACTOME COMPLEMENT CASCADE 54 8.61e-02 1.35e-01 2.38e-01
REACTOME SIGNAL AMPLIFICATION 33 8.62e-02 -1.73e-01 2.38e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2 117 8.69e-02 -9.16e-02 2.39e-01
REACTOME DIGESTION OF DIETARY LIPID 7 8.69e-02 3.74e-01 2.39e-01
REACTOME EPH EPHRIN SIGNALING 90 8.76e-02 -1.04e-01 2.40e-01
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS 28 8.79e-02 -1.86e-01 2.41e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL 14 8.80e-02 -2.63e-01 2.41e-01
REACTOME INTERLEUKIN 12 FAMILY SIGNALING 53 8.97e-02 -1.35e-01 2.45e-01
REACTOME INTERLEUKIN 9 SIGNALING 7 9.00e-02 -3.70e-01 2.46e-01
REACTOME CHOLINE CATABOLISM 6 9.04e-02 3.99e-01 2.46e-01
REACTOME SIGNALING BY TGFB FAMILY MEMBERS 119 9.07e-02 -8.98e-02 2.47e-01
REACTOME BICARBONATE TRANSPORTERS 10 9.09e-02 3.09e-01 2.47e-01
REACTOME MELANIN BIOSYNTHESIS 5 9.12e-02 4.36e-01 2.47e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM 50 9.19e-02 1.38e-01 2.48e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3 94 9.23e-02 -1.00e-01 2.49e-01
REACTOME DOWNREGULATION OF ERBB2 SIGNALING 29 9.23e-02 -1.81e-01 2.49e-01
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE 25 9.36e-02 -1.94e-01 2.52e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL 14 9.38e-02 2.59e-01 2.52e-01
REACTOME CRMPS IN SEMA3A SIGNALING 15 9.41e-02 2.50e-01 2.52e-01
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS 77 9.41e-02 -1.10e-01 2.52e-01
REACTOME SNRNP ASSEMBLY 53 9.52e-02 -1.32e-01 2.55e-01
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION 6 9.56e-02 3.93e-01 2.55e-01
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES 80 9.58e-02 -1.08e-01 2.55e-01
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS 23 9.58e-02 2.01e-01 2.55e-01
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION 15 9.61e-02 -2.48e-01 2.55e-01
REACTOME HEDGEHOG ON STATE 85 9.63e-02 -1.04e-01 2.56e-01
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 11 9.66e-02 -2.89e-01 2.56e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ 6 9.70e-02 -3.91e-01 2.56e-01
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA 63 9.73e-02 -1.21e-01 2.57e-01
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS 28 9.79e-02 -1.81e-01 2.58e-01
REACTOME INTERLEUKIN 10 SIGNALING 43 9.79e-02 -1.46e-01 2.58e-01
REACTOME DUAL INCISION IN TC NER 63 9.82e-02 -1.20e-01 2.58e-01
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION 37 9.86e-02 -1.57e-01 2.58e-01
REACTOME EARLY PHASE OF HIV LIFE CYCLE 14 9.87e-02 -2.55e-01 2.58e-01
REACTOME INTERLEUKIN 1 PROCESSING 9 9.88e-02 -3.18e-01 2.58e-01
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE 22 9.93e-02 2.03e-01 2.59e-01
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY 30 1.00e-01 -1.73e-01 2.61e-01
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE 29 1.01e-01 -1.76e-01 2.62e-01
REACTOME CELL JUNCTION ORGANIZATION 89 1.01e-01 1.01e-01 2.62e-01
REACTOME ALPHA DEFENSINS 6 1.01e-01 3.86e-01 2.62e-01
REACTOME ACYL CHAIN REMODELLING OF PS 22 1.01e-01 2.02e-01 2.62e-01
REACTOME CROSSLINKING OF COLLAGEN FIBRILS 16 1.02e-01 2.36e-01 2.63e-01
REACTOME SIGNALLING TO ERKS 34 1.02e-01 -1.62e-01 2.63e-01
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK 47 1.02e-01 -1.38e-01 2.63e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION 36 1.03e-01 -1.57e-01 2.65e-01
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING 53 1.03e-01 -1.29e-01 2.65e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER 28 1.04e-01 -1.78e-01 2.66e-01
REACTOME GABA B RECEPTOR ACTIVATION 43 1.04e-01 1.43e-01 2.66e-01
REACTOME BUDDING AND MATURATION OF HIV VIRION 28 1.05e-01 -1.77e-01 2.68e-01
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING 9 1.06e-01 3.12e-01 2.68e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS 5 1.06e-01 -4.18e-01 2.68e-01
REACTOME ACTIVATION OF RAS IN B CELLS 5 1.06e-01 -4.18e-01 2.68e-01
REACTOME GLYCOLYSIS 70 1.06e-01 -1.12e-01 2.68e-01
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS 9 1.06e-01 -3.11e-01 2.68e-01
REACTOME PI3K AKT ACTIVATION 9 1.06e-01 -3.11e-01 2.68e-01
REACTOME INTEGRATION OF PROVIRUS 9 1.06e-01 -3.11e-01 2.68e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES 14 1.06e-01 -2.49e-01 2.68e-01
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING 30 1.06e-01 1.70e-01 2.68e-01
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL 129 1.07e-01 -8.23e-02 2.68e-01
REACTOME CHYLOMICRON ASSEMBLY 10 1.07e-01 2.94e-01 2.70e-01
REACTOME ETHANOL OXIDATION 12 1.09e-01 -2.67e-01 2.73e-01
REACTOME REGULATION BY C FLIP 11 1.09e-01 -2.79e-01 2.73e-01
REACTOME HOST INTERACTIONS OF HIV FACTORS 127 1.09e-01 -8.23e-02 2.73e-01
REACTOME MET ACTIVATES PI3K AKT SIGNALING 6 1.09e-01 -3.77e-01 2.73e-01
REACTOME SIGNALING BY ALK 26 1.10e-01 -1.81e-01 2.75e-01
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION 41 1.11e-01 -1.44e-01 2.77e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION 30 1.12e-01 -1.68e-01 2.78e-01
REACTOME SIGNALING BY FGFR1 IN DISEASE 38 1.12e-01 -1.49e-01 2.78e-01
REACTOME FATTY ACID METABOLISM 170 1.12e-01 -7.06e-02 2.78e-01
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY 10 1.12e-01 2.90e-01 2.78e-01
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM 13 1.12e-01 -2.54e-01 2.78e-01
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS 6 1.13e-01 3.73e-01 2.80e-01
REACTOME GAB1 SIGNALOSOME 17 1.14e-01 -2.22e-01 2.80e-01
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII 15 1.14e-01 -2.36e-01 2.80e-01
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 73 1.14e-01 -1.07e-01 2.80e-01
REACTOME SERINE BIOSYNTHESIS 9 1.14e-01 -3.04e-01 2.80e-01
REACTOME TRNA AMINOACYLATION 40 1.15e-01 -1.44e-01 2.82e-01
REACTOME RHOU GTPASE CYCLE 37 1.16e-01 -1.49e-01 2.84e-01
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD 7 1.17e-01 3.42e-01 2.86e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS 46 1.17e-01 -1.34e-01 2.86e-01
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING 145 1.18e-01 -7.53e-02 2.86e-01
REACTOME SIGNALING BY ERBB2 IN CANCER 26 1.18e-01 -1.77e-01 2.86e-01
REACTOME P75NTR REGULATES AXONOGENESIS 9 1.18e-01 3.01e-01 2.86e-01
REACTOME FORMATION OF INCISION COMPLEX IN GG NER 40 1.18e-01 -1.43e-01 2.86e-01
REACTOME HEME SIGNALING 47 1.18e-01 -1.32e-01 2.86e-01
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA 9 1.18e-01 -3.01e-01 2.86e-01
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION 8 1.19e-01 -3.19e-01 2.86e-01
REACTOME HEME DEGRADATION 15 1.20e-01 2.32e-01 2.89e-01
REACTOME NICOTINAMIDE SALVAGING 19 1.20e-01 2.06e-01 2.89e-01
REACTOME DECTIN 2 FAMILY 26 1.21e-01 1.76e-01 2.91e-01
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS 20 1.21e-01 -2.00e-01 2.91e-01
REACTOME ATTENUATION PHASE 27 1.22e-01 -1.72e-01 2.91e-01
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS 8 1.22e-01 3.16e-01 2.91e-01
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES 77 1.22e-01 1.02e-01 2.91e-01
REACTOME TRANSPORT OF ORGANIC ANIONS 10 1.22e-01 2.82e-01 2.91e-01
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 12 1.22e-01 -2.58e-01 2.91e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE 15 1.23e-01 -2.30e-01 2.93e-01
REACTOME FANCONI ANEMIA PATHWAY 35 1.23e-01 -1.50e-01 2.93e-01
REACTOME CA2 PATHWAY 62 1.24e-01 -1.13e-01 2.95e-01
REACTOME CD28 CO STIMULATION 32 1.25e-01 -1.57e-01 2.97e-01
REACTOME FRS MEDIATED FGFR2 SIGNALING 24 1.26e-01 1.81e-01 2.97e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS 6 1.26e-01 -3.61e-01 2.98e-01
REACTOME SYNTHESIS OF PG 8 1.27e-01 -3.12e-01 2.99e-01
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1 16 1.27e-01 -2.20e-01 2.99e-01
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY 11 1.27e-01 2.66e-01 2.99e-01
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS 19 1.27e-01 -2.02e-01 2.99e-01
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON 17 1.29e-01 -2.13e-01 3.01e-01
REACTOME BIOSYNTHESIS OF MARESINS 8 1.29e-01 3.10e-01 3.01e-01
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM 78 1.29e-01 -9.95e-02 3.01e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE 5 1.29e-01 3.92e-01 3.01e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES 15 1.29e-01 -2.26e-01 3.01e-01
REACTOME BIOLOGICAL OXIDATIONS 210 1.30e-01 6.05e-02 3.04e-01
REACTOME PI3K EVENTS IN ERBB4 SIGNALING 10 1.31e-01 -2.76e-01 3.04e-01
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION 31 1.31e-01 -1.57e-01 3.04e-01
REACTOME CYTOSOLIC TRNA AMINOACYLATION 22 1.31e-01 -1.86e-01 3.04e-01
REACTOME RHOJ GTPASE CYCLE 51 1.32e-01 -1.22e-01 3.05e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING 30 1.32e-01 -1.59e-01 3.05e-01
REACTOME P38MAPK EVENTS 13 1.32e-01 -2.41e-01 3.05e-01
REACTOME GP1B IX V ACTIVATION SIGNALLING 11 1.34e-01 -2.61e-01 3.08e-01
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS 9 1.34e-01 2.89e-01 3.08e-01
REACTOME RORA ACTIVATES GENE EXPRESSION 17 1.35e-01 -2.10e-01 3.09e-01
REACTOME RET SIGNALING 40 1.35e-01 -1.37e-01 3.10e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER 28 1.35e-01 -1.63e-01 3.10e-01
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN 35 1.35e-01 -1.46e-01 3.10e-01
REACTOME ACTIVATION OF SMO 18 1.38e-01 -2.02e-01 3.15e-01
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME 59 1.38e-01 -1.12e-01 3.15e-01
REACTOME DEFECTS IN BIOTIN BTN METABOLISM 8 1.38e-01 -3.03e-01 3.15e-01
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE 81 1.38e-01 -9.53e-02 3.15e-01
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING 23 1.39e-01 -1.78e-01 3.16e-01
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY 8 1.40e-01 -3.02e-01 3.17e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING 5 1.43e-01 -3.78e-01 3.24e-01
REACTOME TRIGLYCERIDE BIOSYNTHESIS 12 1.43e-01 2.44e-01 3.25e-01
REACTOME SIGNALING BY LRP5 MUTANTS 6 1.44e-01 3.45e-01 3.25e-01
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS 41 1.44e-01 -1.32e-01 3.26e-01
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN 13 1.45e-01 -2.34e-01 3.26e-01
REACTOME INTERLEUKIN 2 SIGNALING 11 1.45e-01 -2.54e-01 3.26e-01
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY 54 1.45e-01 -1.15e-01 3.26e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS 11 1.46e-01 -2.53e-01 3.27e-01
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION 9 1.46e-01 -2.80e-01 3.27e-01
REACTOME TRAIL SIGNALING 8 1.46e-01 -2.97e-01 3.27e-01
REACTOME NICOTINATE METABOLISM 31 1.46e-01 1.51e-01 3.27e-01
REACTOME NRCAM INTERACTIONS 6 1.49e-01 3.40e-01 3.34e-01
REACTOME FASL CD95L SIGNALING 5 1.50e-01 -3.71e-01 3.36e-01
REACTOME ACTIVATION OF TRKA RECEPTORS 6 1.51e-01 3.39e-01 3.36e-01
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX 13 1.53e-01 -2.29e-01 3.40e-01
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION 6 1.54e-01 -3.36e-01 3.41e-01
REACTOME WNT MEDIATED ACTIVATION OF DVL 8 1.54e-01 -2.91e-01 3.43e-01
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT 31 1.57e-01 -1.47e-01 3.47e-01
REACTOME ACTIVATION OF BH3 ONLY PROTEINS 30 1.58e-01 -1.49e-01 3.48e-01
REACTOME SHC MEDIATED CASCADE FGFR4 19 1.58e-01 1.87e-01 3.48e-01
REACTOME SIGNALING BY ERBB4 57 1.60e-01 -1.08e-01 3.52e-01
REACTOME HYALURONAN UPTAKE AND DEGRADATION 12 1.60e-01 -2.34e-01 3.53e-01
REACTOME DUAL INCISION IN GG NER 39 1.61e-01 -1.30e-01 3.53e-01
REACTOME POLO LIKE KINASE MEDIATED EVENTS 16 1.61e-01 -2.03e-01 3.53e-01
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR 19 1.61e-01 -1.86e-01 3.53e-01
REACTOME SYNAPTIC ADHESION LIKE MOLECULES 19 1.61e-01 1.86e-01 3.53e-01
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY 36 1.62e-01 -1.35e-01 3.54e-01
REACTOME COENZYME A BIOSYNTHESIS 8 1.62e-01 -2.85e-01 3.55e-01
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE 39 1.63e-01 -1.29e-01 3.55e-01
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 1.63e-01 2.08e-01 3.55e-01
REACTOME P75NTR SIGNALS VIA NF KB 15 1.63e-01 -2.08e-01 3.55e-01
REACTOME HIV TRANSCRIPTION INITIATION 43 1.63e-01 -1.23e-01 3.55e-01
REACTOME PI 3K CASCADE FGFR3 17 1.63e-01 1.95e-01 3.55e-01
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER 25 1.64e-01 -1.61e-01 3.55e-01
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS 122 1.64e-01 -7.29e-02 3.55e-01
REACTOME RHOF GTPASE CYCLE 40 1.64e-01 -1.27e-01 3.55e-01
REACTOME CELLULAR RESPONSE TO HYPOXIA 74 1.64e-01 -9.35e-02 3.55e-01
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS 5 1.66e-01 3.58e-01 3.58e-01
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS 91 1.66e-01 8.40e-02 3.58e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES 61 1.67e-01 -1.02e-01 3.60e-01
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING 16 1.68e-01 -1.99e-01 3.61e-01
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN 15 1.68e-01 -2.06e-01 3.61e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE 74 1.68e-01 9.26e-02 3.61e-01
REACTOME REGULATION OF NF KAPPA B SIGNALING 17 1.69e-01 -1.93e-01 3.61e-01
REACTOME ORC1 REMOVAL FROM CHROMATIN 70 1.69e-01 -9.50e-02 3.62e-01
REACTOME CYP2E1 REACTIONS 10 1.70e-01 2.51e-01 3.62e-01
REACTOME CREB PHOSPHORYLATION 6 1.70e-01 -3.23e-01 3.63e-01
REACTOME DISEASES OF MISMATCH REPAIR MMR 5 1.70e-01 -3.54e-01 3.63e-01
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS 43 1.71e-01 -1.21e-01 3.64e-01
REACTOME GLUCOSE METABOLISM 90 1.71e-01 -8.34e-02 3.64e-01
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS 7 1.71e-01 -2.98e-01 3.64e-01
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT 18 1.73e-01 -1.86e-01 3.66e-01
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC 21 1.73e-01 -1.72e-01 3.66e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS 5 1.73e-01 -3.52e-01 3.66e-01
REACTOME RHOD GTPASE CYCLE 49 1.74e-01 -1.12e-01 3.67e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST 14 1.74e-01 -2.10e-01 3.67e-01
REACTOME PI 3K CASCADE FGFR1 21 1.74e-01 1.71e-01 3.67e-01
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS 6 1.75e-01 3.20e-01 3.68e-01
REACTOME ACYL CHAIN REMODELLING OF PC 27 1.76e-01 1.50e-01 3.69e-01
REACTOME LIPID PARTICLE ORGANIZATION 6 1.76e-01 3.19e-01 3.69e-01
REACTOME TRAF6 MEDIATED NF KB ACTIVATION 24 1.77e-01 -1.59e-01 3.69e-01
REACTOME FRS MEDIATED FGFR4 SIGNALING 21 1.77e-01 1.70e-01 3.69e-01
REACTOME DISEASES OF METABOLISM 237 1.77e-01 5.09e-02 3.69e-01
REACTOME ION CHANNEL TRANSPORT 172 1.77e-01 5.97e-02 3.69e-01
REACTOME HS GAG DEGRADATION 19 1.79e-01 1.78e-01 3.72e-01
REACTOME NEGATIVE REGULATION OF MET ACTIVITY 20 1.79e-01 -1.74e-01 3.72e-01
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS 43 1.79e-01 -1.18e-01 3.73e-01
REACTOME PROPIONYL COA CATABOLISM 5 1.80e-01 -3.46e-01 3.73e-01
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION 10 1.81e-01 -2.44e-01 3.75e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING 28 1.81e-01 1.46e-01 3.75e-01
REACTOME RHO GTPASES ACTIVATE ROCKS 19 1.81e-01 -1.77e-01 3.75e-01
REACTOME RAP1 SIGNALLING 16 1.81e-01 -1.93e-01 3.75e-01
REACTOME TIGHT JUNCTION INTERACTIONS 29 1.82e-01 1.43e-01 3.75e-01
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING 32 1.82e-01 1.36e-01 3.75e-01
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS 35 1.82e-01 -1.30e-01 3.75e-01
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION 10 1.83e-01 -2.43e-01 3.76e-01
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA 54 1.83e-01 -1.05e-01 3.76e-01
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR 11 1.85e-01 -2.31e-01 3.80e-01
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES 255 1.86e-01 4.81e-02 3.81e-01
REACTOME NEPHRIN FAMILY INTERACTIONS 22 1.87e-01 -1.63e-01 3.81e-01
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES 16 1.87e-01 -1.90e-01 3.82e-01
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM 21 1.87e-01 -1.66e-01 3.82e-01
REACTOME METHIONINE SALVAGE PATHWAY 6 1.88e-01 -3.11e-01 3.82e-01
REACTOME DEFECTIVE LFNG CAUSES SCDO3 5 1.90e-01 3.38e-01 3.87e-01
REACTOME BIOTIN TRANSPORT AND METABOLISM 10 1.91e-01 -2.39e-01 3.87e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS 8 1.91e-01 -2.67e-01 3.87e-01
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS 33 1.92e-01 -1.31e-01 3.89e-01
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS 7 1.92e-01 -2.85e-01 3.89e-01
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL 13 1.92e-01 -2.09e-01 3.89e-01
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH 6 1.92e-01 -3.07e-01 3.89e-01
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS 9 1.93e-01 -2.51e-01 3.89e-01
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE 20 1.93e-01 -1.68e-01 3.89e-01
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7 7 1.94e-01 -2.84e-01 3.90e-01
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY 14 1.94e-01 2.00e-01 3.91e-01
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX 57 1.95e-01 -9.92e-02 3.92e-01
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS 9 1.96e-01 2.49e-01 3.92e-01
REACTOME TRANSPORT OF FATTY ACIDS 8 1.97e-01 2.64e-01 3.93e-01
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS 93 1.97e-01 7.74e-02 3.93e-01
REACTOME DEFECTIVE CHST6 CAUSES MCDC1 8 1.97e-01 2.63e-01 3.93e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES 51 1.99e-01 1.04e-01 3.96e-01
REACTOME OAS ANTIVIRAL RESPONSE 8 1.99e-01 2.62e-01 3.97e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS 8 2.01e-01 -2.61e-01 4.00e-01
REACTOME STABILIZATION OF P53 56 2.01e-01 -9.87e-02 4.01e-01
REACTOME ACTIVATION OF C3 AND C5 6 2.03e-01 3.00e-01 4.03e-01
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES 101 2.04e-01 7.32e-02 4.04e-01
REACTOME NEGATIVE REGULATION OF FLT3 15 2.04e-01 -1.89e-01 4.04e-01
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING 38 2.05e-01 -1.19e-01 4.04e-01
REACTOME MIRO GTPASE CYCLE 8 2.05e-01 -2.59e-01 4.04e-01
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION 98 2.06e-01 -7.40e-02 4.05e-01
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER 7 2.06e-01 -2.76e-01 4.05e-01
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY 10 2.06e-01 -2.31e-01 4.06e-01
REACTOME DEADENYLATION OF MRNA 25 2.07e-01 -1.46e-01 4.07e-01
REACTOME RUNX3 REGULATES NOTCH SIGNALING 13 2.07e-01 -2.02e-01 4.07e-01
REACTOME POLYMERASE SWITCHING 13 2.08e-01 -2.02e-01 4.07e-01
REACTOME VOLTAGE GATED POTASSIUM CHANNELS 42 2.08e-01 1.12e-01 4.07e-01
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA 15 2.08e-01 -1.88e-01 4.07e-01
REACTOME REGULATION OF PTEN LOCALIZATION 8 2.08e-01 -2.57e-01 4.07e-01
REACTOME ENOS ACTIVATION 11 2.09e-01 -2.19e-01 4.07e-01
REACTOME RECEPTOR MEDIATED MITOPHAGY 10 2.10e-01 -2.29e-01 4.10e-01
REACTOME TRANSCRIPTION OF THE HIV GENOME 66 2.11e-01 -8.90e-02 4.11e-01
REACTOME CIPROFLOXACIN ADME 5 2.12e-01 3.23e-01 4.11e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM 38 2.12e-01 1.17e-01 4.11e-01
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1 9 2.13e-01 -2.40e-01 4.13e-01
REACTOME INDUCTION OF CELL CELL FUSION 12 2.13e-01 2.08e-01 4.13e-01
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING 5 2.13e-01 -3.21e-01 4.13e-01
REACTOME TRNA PROCESSING IN THE NUCLEUS 58 2.14e-01 -9.43e-02 4.14e-01
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT 5 2.15e-01 3.20e-01 4.15e-01
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION 20 2.15e-01 -1.60e-01 4.15e-01
REACTOME CELLULAR RESPONSE TO HEAT STRESS 99 2.16e-01 -7.19e-02 4.16e-01
REACTOME IRAK1 RECRUITS IKK COMPLEX 12 2.17e-01 -2.06e-01 4.17e-01
REACTOME RND2 GTPASE CYCLE 42 2.17e-01 -1.10e-01 4.17e-01
REACTOME MAP2K AND MAPK ACTIVATION 38 2.17e-01 -1.16e-01 4.17e-01
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE 10 2.18e-01 -2.25e-01 4.18e-01
REACTOME DARPP 32 EVENTS 24 2.18e-01 -1.45e-01 4.18e-01
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT 19 2.19e-01 -1.63e-01 4.18e-01
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO 10 2.19e-01 2.25e-01 4.18e-01
REACTOME G ALPHA S SIGNALLING EVENTS 155 2.19e-01 5.72e-02 4.19e-01
REACTOME LATE SARS COV 2 INFECTION EVENTS 67 2.20e-01 -8.67e-02 4.19e-01
REACTOME EPHB MEDIATED FORWARD SIGNALING 41 2.21e-01 -1.11e-01 4.20e-01
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE 11 2.21e-01 2.13e-01 4.21e-01
REACTOME SYNTHESIS OF PC 27 2.22e-01 -1.36e-01 4.21e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM 16 2.22e-01 -1.76e-01 4.21e-01
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN 5 2.22e-01 -3.15e-01 4.21e-01
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA 17 2.22e-01 -1.71e-01 4.21e-01
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER 49 2.22e-01 -1.01e-01 4.21e-01
REACTOME SIGNALING BY RETINOIC ACID 41 2.25e-01 -1.10e-01 4.24e-01
REACTOME INTRA GOLGI TRAFFIC 43 2.27e-01 -1.07e-01 4.27e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE 21 2.27e-01 -1.52e-01 4.27e-01
REACTOME TRIGLYCERIDE CATABOLISM 23 2.30e-01 1.45e-01 4.33e-01
REACTOME OTHER INTERLEUKIN SIGNALING 24 2.31e-01 -1.41e-01 4.34e-01
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS 35 2.31e-01 -1.17e-01 4.34e-01
REACTOME CELL CELL JUNCTION ORGANIZATION 64 2.32e-01 8.65e-02 4.35e-01
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS 9 2.32e-01 -2.30e-01 4.35e-01
REACTOME LDL REMODELING 6 2.32e-01 2.82e-01 4.35e-01
REACTOME INTERLEUKIN 27 SIGNALING 11 2.34e-01 -2.07e-01 4.38e-01
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX 10 2.35e-01 -2.17e-01 4.38e-01
REACTOME RHOC GTPASE CYCLE 71 2.35e-01 -8.15e-02 4.38e-01
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 11 2.35e-01 -2.07e-01 4.38e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42 19 2.35e-01 -1.57e-01 4.38e-01
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS 5 2.36e-01 3.06e-01 4.38e-01
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS 16 2.36e-01 -1.71e-01 4.39e-01
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS 33 2.37e-01 -1.19e-01 4.40e-01
REACTOME RHOBTB1 GTPASE CYCLE 22 2.38e-01 -1.45e-01 4.40e-01
REACTOME ASSEMBLY OF THE HIV VIRION 16 2.38e-01 -1.70e-01 4.41e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION 45 2.38e-01 -1.02e-01 4.41e-01
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY 5 2.39e-01 3.04e-01 4.41e-01
REACTOME GABA RECEPTOR ACTIVATION 57 2.40e-01 8.99e-02 4.43e-01
REACTOME SIGNALING BY ERBB2 ECD MUTANTS 16 2.40e-01 -1.70e-01 4.43e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE 5 2.40e-01 -3.03e-01 4.43e-01
REACTOME ERK MAPK TARGETS 20 2.43e-01 -1.51e-01 4.46e-01
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER 25 2.43e-01 -1.35e-01 4.46e-01
REACTOME RND3 GTPASE CYCLE 41 2.43e-01 -1.05e-01 4.46e-01
REACTOME VITAMIN D CALCIFEROL METABOLISM 12 2.44e-01 -1.94e-01 4.46e-01
REACTOME PARACETAMOL ADME 26 2.44e-01 1.32e-01 4.46e-01
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS 39 2.45e-01 -1.08e-01 4.48e-01
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS 60 2.45e-01 -8.67e-02 4.48e-01
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES 12 2.46e-01 -1.93e-01 4.49e-01
REACTOME FCERI MEDIATED CA 2 MOBILIZATION 30 2.47e-01 -1.22e-01 4.50e-01
REACTOME REGULATION OF RAS BY GAPS 66 2.47e-01 -8.23e-02 4.50e-01
REACTOME XENOBIOTICS 22 2.48e-01 1.42e-01 4.51e-01
REACTOME TRNA PROCESSING 105 2.49e-01 -6.51e-02 4.52e-01
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE 9 2.49e-01 2.22e-01 4.52e-01
REACTOME FOXO MEDIATED TRANSCRIPTION 65 2.50e-01 -8.25e-02 4.53e-01
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS 50 2.51e-01 -9.38e-02 4.55e-01
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS 29 2.52e-01 -1.23e-01 4.55e-01
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING 103 2.52e-01 -6.53e-02 4.55e-01
REACTOME MET RECEPTOR RECYCLING 10 2.53e-01 -2.09e-01 4.56e-01
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION 24 2.53e-01 -1.35e-01 4.56e-01
REACTOME RHO GTPASES ACTIVATE PAKS 19 2.53e-01 -1.51e-01 4.56e-01
REACTOME PHASE 3 RAPID REPOLARISATION 8 2.54e-01 -2.33e-01 4.56e-01
REACTOME HDR THROUGH MMEJ ALT NHEJ 12 2.55e-01 -1.90e-01 4.58e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN 21 2.55e-01 -1.43e-01 4.58e-01
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA 11 2.55e-01 1.98e-01 4.58e-01
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM 9 2.56e-01 2.19e-01 4.58e-01
REACTOME 2 LTR CIRCLE FORMATION 7 2.56e-01 -2.48e-01 4.59e-01
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB 10 2.62e-01 2.05e-01 4.69e-01
REACTOME EXTENSION OF TELOMERES 49 2.63e-01 -9.24e-02 4.69e-01
REACTOME NGF INDEPENDANT TRKA ACTIVATION 5 2.63e-01 2.89e-01 4.69e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA 25 2.63e-01 -1.29e-01 4.69e-01
REACTOME ARMS MEDIATED ACTIVATION 7 2.64e-01 2.44e-01 4.70e-01
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN 5 2.65e-01 -2.88e-01 4.70e-01
REACTOME GPVI MEDIATED ACTIVATION CASCADE 35 2.65e-01 -1.09e-01 4.70e-01
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE 11 2.66e-01 1.94e-01 4.70e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING 16 2.66e-01 -1.61e-01 4.70e-01
REACTOME SIGNALING BY ACTIVIN 15 2.66e-01 -1.66e-01 4.71e-01
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION 10 2.67e-01 -2.03e-01 4.72e-01
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX 8 2.70e-01 -2.25e-01 4.76e-01
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE 19 2.70e-01 -1.46e-01 4.76e-01
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM 7 2.70e-01 -2.41e-01 4.76e-01
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES 34 2.71e-01 -1.09e-01 4.76e-01
REACTOME REGULATION OF BETA CELL DEVELOPMENT 41 2.72e-01 -9.91e-02 4.79e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG 7 2.73e-01 -2.39e-01 4.80e-01
REACTOME CREATINE METABOLISM 9 2.74e-01 2.11e-01 4.80e-01
REACTOME FCGR ACTIVATION 11 2.74e-01 -1.91e-01 4.80e-01
REACTOME CA2 ACTIVATED K CHANNELS 9 2.75e-01 2.10e-01 4.82e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 22 2.76e-01 -1.34e-01 4.82e-01
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS 38 2.76e-01 -1.02e-01 4.82e-01
REACTOME NUCLEOTIDE CATABOLISM 35 2.77e-01 -1.06e-01 4.84e-01
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION 5 2.77e-01 -2.81e-01 4.84e-01
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS 6 2.80e-01 -2.55e-01 4.87e-01
REACTOME PYRUVATE METABOLISM 29 2.80e-01 -1.16e-01 4.87e-01
REACTOME FLT3 SIGNALING BY CBL MUTANTS 7 2.80e-01 -2.36e-01 4.87e-01
REACTOME SIGNALING BY INSULIN RECEPTOR 80 2.80e-01 -6.98e-02 4.87e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER 8 2.82e-01 -2.20e-01 4.88e-01
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS 29 2.82e-01 -1.15e-01 4.88e-01
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION 7 2.82e-01 2.35e-01 4.88e-01
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS 5 2.83e-01 -2.77e-01 4.88e-01
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY 10 2.83e-01 -1.96e-01 4.89e-01
REACTOME LGI ADAM INTERACTIONS 14 2.84e-01 1.66e-01 4.89e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION 15 2.84e-01 -1.60e-01 4.89e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS 29 2.84e-01 -1.15e-01 4.89e-01
REACTOME ACYL CHAIN REMODELLING OF PG 18 2.85e-01 1.46e-01 4.90e-01
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS 20 2.86e-01 -1.38e-01 4.91e-01
REACTOME REGULATION OF IFNG SIGNALING 14 2.87e-01 -1.64e-01 4.91e-01
REACTOME SHC MEDIATED CASCADE FGFR3 17 2.87e-01 1.49e-01 4.91e-01
REACTOME FERTILIZATION 26 2.87e-01 1.21e-01 4.91e-01
REACTOME KILLING MECHANISMS 11 2.88e-01 1.85e-01 4.91e-01
REACTOME DEGRADATION OF AXIN 54 2.88e-01 -8.36e-02 4.91e-01
REACTOME CELLULAR HEXOSE TRANSPORT 21 2.88e-01 1.34e-01 4.91e-01
REACTOME SHC MEDIATED CASCADE FGFR1 21 2.88e-01 1.34e-01 4.91e-01
REACTOME GLYCOGEN SYNTHESIS 13 2.88e-01 -1.70e-01 4.91e-01
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT 15 2.91e-01 1.57e-01 4.95e-01
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS 46 2.91e-01 -8.99e-02 4.95e-01
REACTOME NONCANONICAL ACTIVATION OF NOTCH3 8 2.92e-01 -2.15e-01 4.95e-01
REACTOME ADRENOCEPTORS 9 2.92e-01 2.03e-01 4.95e-01
REACTOME VITAMINS 6 2.92e-01 -2.48e-01 4.95e-01
REACTOME SIGNALING BY NTRK3 TRKC 17 2.93e-01 -1.47e-01 4.96e-01
REACTOME RHO GTPASES ACTIVATE CIT 19 2.93e-01 -1.39e-01 4.96e-01
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION 10 2.94e-01 1.91e-01 4.97e-01
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES 16 2.95e-01 1.51e-01 4.97e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP 12 2.95e-01 -1.75e-01 4.97e-01
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS 17 2.96e-01 -1.46e-01 4.98e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS 13 2.96e-01 1.67e-01 4.99e-01
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX 39 2.97e-01 -9.64e-02 5.00e-01
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS 13 2.98e-01 -1.67e-01 5.00e-01
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION 10 2.99e-01 1.90e-01 5.00e-01
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION 14 2.99e-01 -1.60e-01 5.00e-01
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX 14 2.99e-01 -1.60e-01 5.00e-01
REACTOME NETRIN MEDIATED REPULSION SIGNALS 8 2.99e-01 2.12e-01 5.00e-01
REACTOME SYNTHESIS OF LIPOXINS LX 6 2.99e-01 -2.45e-01 5.00e-01
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES 17 3.00e-01 -1.45e-01 5.01e-01
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA 36 3.01e-01 -9.96e-02 5.02e-01
REACTOME REGULATION OF NPAS4 GENE EXPRESSION 13 3.01e-01 -1.66e-01 5.02e-01
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG 5 3.02e-01 2.67e-01 5.02e-01
REACTOME IKBA VARIANT LEADS TO EDA ID 6 3.02e-01 -2.43e-01 5.02e-01
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX 36 3.03e-01 -9.93e-02 5.02e-01
REACTOME DAP12 SIGNALING 27 3.03e-01 -1.14e-01 5.03e-01
REACTOME ALK MUTANTS BIND TKIS 12 3.04e-01 -1.71e-01 5.04e-01
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS 45 3.05e-01 -8.84e-02 5.04e-01
REACTOME SIGNALING BY RNF43 MUTANTS 8 3.05e-01 2.09e-01 5.04e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 16 3.06e-01 -1.48e-01 5.05e-01
REACTOME NUCLEAR ENVELOPE BREAKDOWN 52 3.06e-01 -8.21e-02 5.05e-01
REACTOME HISTIDINE CATABOLISM 8 3.06e-01 2.09e-01 5.05e-01
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION 23 3.07e-01 1.23e-01 5.05e-01
REACTOME CREB3 FACTORS ACTIVATE GENES 8 3.07e-01 -2.09e-01 5.05e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING 23 3.07e-01 1.23e-01 5.05e-01
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS 32 3.08e-01 -1.04e-01 5.05e-01
REACTOME HDL REMODELING 10 3.10e-01 1.86e-01 5.07e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE 5 3.10e-01 -2.62e-01 5.07e-01
REACTOME FRS MEDIATED FGFR3 SIGNALING 19 3.10e-01 1.34e-01 5.07e-01
REACTOME MET ACTIVATES RAP1 AND RAC1 11 3.11e-01 -1.77e-01 5.07e-01
REACTOME HIV TRANSCRIPTION ELONGATION 42 3.11e-01 -9.04e-02 5.07e-01
REACTOME DISEASES OF BASE EXCISION REPAIR 5 3.12e-01 2.61e-01 5.10e-01
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS 41 3.14e-01 -9.09e-02 5.11e-01
REACTOME PEROXISOMAL LIPID METABOLISM 28 3.14e-01 -1.10e-01 5.11e-01
REACTOME DNA STRAND ELONGATION 31 3.14e-01 -1.04e-01 5.11e-01
REACTOME RHOT1 GTPASE CYCLE 5 3.15e-01 -2.60e-01 5.11e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS 9 3.15e-01 -1.93e-01 5.11e-01
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN 15 3.15e-01 -1.50e-01 5.11e-01
REACTOME SIGNALING BY FGFR2 IN DISEASE 42 3.16e-01 8.95e-02 5.11e-01
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN 76 3.16e-01 -6.66e-02 5.11e-01
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION 9 3.16e-01 -1.93e-01 5.11e-01
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A 26 3.16e-01 -1.14e-01 5.11e-01
REACTOME FORMATION OF AXIAL MESODERM 14 3.18e-01 1.54e-01 5.12e-01
REACTOME FORMATION OF LATERAL PLATE MESODERM 5 3.18e-01 -2.58e-01 5.12e-01
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES 33 3.19e-01 1.00e-01 5.14e-01
REACTOME INTESTINAL ABSORPTION 5 3.19e-01 2.57e-01 5.14e-01
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS 11 3.20e-01 -1.73e-01 5.15e-01
REACTOME PARASITE INFECTION 57 3.23e-01 -7.58e-02 5.18e-01
REACTOME CHOLESTEROL BIOSYNTHESIS 25 3.24e-01 -1.14e-01 5.19e-01
REACTOME PHOSPHORYLATION OF THE APC C 20 3.24e-01 -1.27e-01 5.19e-01
REACTOME FORMATION OF APOPTOSOME 10 3.24e-01 -1.80e-01 5.19e-01
REACTOME MUCOPOLYSACCHARIDOSES 10 3.24e-01 -1.80e-01 5.19e-01
REACTOME MISMATCH REPAIR 15 3.25e-01 -1.47e-01 5.19e-01
REACTOME ION HOMEOSTASIS 52 3.25e-01 7.89e-02 5.19e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES 29 3.29e-01 1.05e-01 5.26e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE 8 3.30e-01 1.99e-01 5.26e-01
REACTOME SIGNALING BY FGFR4 IN DISEASE 11 3.30e-01 -1.69e-01 5.26e-01
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE 20 3.31e-01 -1.25e-01 5.27e-01
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING 6 3.33e-01 -2.28e-01 5.29e-01
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS 6 3.33e-01 2.28e-01 5.29e-01
REACTOME CELLULAR RESPONSE TO STARVATION 147 3.35e-01 -4.61e-02 5.31e-01
REACTOME RAS PROCESSING 22 3.35e-01 -1.19e-01 5.31e-01
REACTOME P2Y RECEPTORS 9 3.36e-01 -1.85e-01 5.31e-01
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION 193 3.36e-01 4.02e-02 5.31e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS 9 3.38e-01 -1.85e-01 5.33e-01
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 19 3.38e-01 -1.27e-01 5.33e-01
REACTOME TYROSINE CATABOLISM 5 3.38e-01 -2.47e-01 5.33e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS 5 3.39e-01 2.47e-01 5.34e-01
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER 5 3.41e-01 -2.46e-01 5.37e-01
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA 5 3.42e-01 -2.45e-01 5.37e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS 12 3.42e-01 -1.58e-01 5.37e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 25 3.43e-01 -1.10e-01 5.38e-01
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX 32 3.44e-01 -9.66e-02 5.39e-01
REACTOME SLC TRANSPORTER DISORDERS 94 3.45e-01 5.64e-02 5.39e-01
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX 29 3.45e-01 -1.01e-01 5.39e-01
REACTOME RRNA PROCESSING 192 3.45e-01 -3.95e-02 5.39e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION 23 3.45e-01 -1.14e-01 5.39e-01
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION 12 3.45e-01 -1.57e-01 5.39e-01
REACTOME VIRAL MESSENGER RNA SYNTHESIS 44 3.46e-01 -8.21e-02 5.40e-01
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES 29 3.46e-01 -1.01e-01 5.40e-01
REACTOME PEPTIDE HORMONE METABOLISM 84 3.47e-01 5.93e-02 5.40e-01
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS 87 3.48e-01 -5.82e-02 5.42e-01
REACTOME SIGNAL TRANSDUCTION BY L1 20 3.50e-01 -1.21e-01 5.43e-01
REACTOME PHENYLALANINE AND TYROSINE METABOLISM 11 3.50e-01 -1.63e-01 5.43e-01
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS 36 3.51e-01 -8.98e-02 5.44e-01
REACTOME CARNITINE METABOLISM 13 3.52e-01 -1.49e-01 5.45e-01
REACTOME MITOTIC TELOPHASE CYTOKINESIS 11 3.52e-01 -1.62e-01 5.45e-01
REACTOME SIGNALLING TO RAS 20 3.53e-01 -1.20e-01 5.46e-01
REACTOME METABOLISM OF AMINE DERIVED HORMONES 17 3.54e-01 1.30e-01 5.46e-01
REACTOME INTERFERON GAMMA SIGNALING 88 3.54e-01 -5.72e-02 5.46e-01
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS 42 3.54e-01 8.26e-02 5.46e-01
REACTOME UNWINDING OF DNA 12 3.54e-01 -1.54e-01 5.46e-01
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION 34 3.55e-01 -9.17e-02 5.46e-01
REACTOME TRANSLESION SYNTHESIS BY POLH 19 3.55e-01 -1.23e-01 5.46e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 29 3.55e-01 9.92e-02 5.46e-01
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA 17 3.56e-01 -1.29e-01 5.47e-01
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION 9 3.57e-01 -1.77e-01 5.48e-01
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION 8 3.58e-01 -1.88e-01 5.48e-01
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL 12 3.59e-01 -1.53e-01 5.49e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING 24 3.59e-01 -1.08e-01 5.49e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING 16 3.60e-01 -1.32e-01 5.49e-01
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE 5 3.60e-01 -2.36e-01 5.50e-01
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING 61 3.60e-01 -6.77e-02 5.50e-01
REACTOME ENDOGENOUS STEROLS 26 3.61e-01 1.03e-01 5.50e-01
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING 8 3.62e-01 -1.86e-01 5.51e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS 35 3.62e-01 -8.90e-02 5.51e-01
REACTOME LDL CLEARANCE 19 3.63e-01 -1.20e-01 5.52e-01
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 54 3.64e-01 -7.13e-02 5.52e-01
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION 9 3.65e-01 -1.75e-01 5.52e-01
REACTOME INFLUENZA INFECTION 149 3.65e-01 -4.30e-02 5.52e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY 19 3.66e-01 1.20e-01 5.53e-01
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS 7 3.66e-01 -1.97e-01 5.53e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS 30 3.66e-01 -9.53e-02 5.53e-01
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS 37 3.66e-01 -8.58e-02 5.53e-01
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE 6 3.67e-01 -2.13e-01 5.53e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY 51 3.68e-01 -7.29e-02 5.55e-01
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES 22 3.69e-01 -1.11e-01 5.55e-01
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS 14 3.69e-01 -1.39e-01 5.55e-01
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING 9 3.70e-01 -1.73e-01 5.55e-01
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY 96 3.70e-01 -5.30e-02 5.55e-01
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS 7 3.73e-01 -1.94e-01 5.59e-01
REACTOME RHOB GTPASE CYCLE 67 3.73e-01 -6.29e-02 5.60e-01
REACTOME MITOPHAGY 28 3.76e-01 -9.67e-02 5.62e-01
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX 9 3.77e-01 -1.70e-01 5.64e-01
REACTOME DEVELOPMENTAL BIOLOGY 1115 3.78e-01 1.57e-02 5.64e-01
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA 9 3.79e-01 -1.69e-01 5.66e-01
REACTOME NUCLEAR IMPORT OF REV PROTEIN 34 3.80e-01 -8.71e-02 5.66e-01
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS 8 3.80e-01 -1.79e-01 5.66e-01
REACTOME SCAVENGING BY CLASS B RECEPTORS 6 3.80e-01 2.07e-01 5.66e-01
REACTOME NEUREXINS AND NEUROLIGINS 51 3.80e-01 7.10e-02 5.66e-01
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS 22 3.81e-01 -1.08e-01 5.66e-01
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS 19 3.83e-01 -1.16e-01 5.68e-01
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION 5 3.83e-01 2.25e-01 5.68e-01
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2 8 3.83e-01 -1.78e-01 5.68e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS 7 3.85e-01 -1.90e-01 5.70e-01
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME 11 3.86e-01 -1.51e-01 5.70e-01
REACTOME MET ACTIVATES PTPN11 5 3.86e-01 -2.24e-01 5.70e-01
REACTOME INTERFERON ALPHA BETA SIGNALING 70 3.87e-01 -5.99e-02 5.70e-01
REACTOME ACYL CHAIN REMODELLING OF PE 29 3.87e-01 9.29e-02 5.70e-01
REACTOME SENSORY PERCEPTION OF SALTY TASTE 6 3.87e-01 2.04e-01 5.70e-01
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B 24 3.88e-01 -1.02e-01 5.71e-01
REACTOME NECTIN NECL TRANS HETERODIMERIZATION 7 3.88e-01 -1.88e-01 5.71e-01
REACTOME REGULATION OF FZD BY UBIQUITINATION 21 3.89e-01 1.09e-01 5.71e-01
REACTOME COHESIN LOADING ONTO CHROMATIN 8 3.90e-01 -1.75e-01 5.73e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 20 3.92e-01 1.11e-01 5.74e-01
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION 20 3.92e-01 -1.11e-01 5.74e-01
REACTOME REPRESSION OF WNT TARGET GENES 14 3.92e-01 1.32e-01 5.74e-01
REACTOME VLDLR INTERNALISATION AND DEGRADATION 16 3.93e-01 -1.23e-01 5.75e-01
REACTOME TERMINAL PATHWAY OF COMPLEMENT 8 3.94e-01 1.74e-01 5.76e-01
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 11 3.95e-01 -1.48e-01 5.77e-01
REACTOME PROCESSING OF INTRONLESS PRE MRNAS 19 3.95e-01 -1.13e-01 5.77e-01
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 16 4.00e-01 -1.22e-01 5.83e-01
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA 15 4.00e-01 -1.26e-01 5.83e-01
REACTOME ORGANIC ANION TRANSPORTERS 10 4.00e-01 1.54e-01 5.83e-01
REACTOME MATURATION OF PROTEIN 3A 9 4.01e-01 -1.62e-01 5.83e-01
REACTOME SPHINGOLIPID METABOLISM 84 4.01e-01 -5.30e-02 5.83e-01
REACTOME CD22 MEDIATED BCR REGULATION 5 4.02e-01 -2.16e-01 5.83e-01
REACTOME GASTRULATION 49 4.03e-01 -6.90e-02 5.85e-01
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN 6 4.05e-01 -1.96e-01 5.87e-01
REACTOME SIGNALING BY NTRK2 TRKB 25 4.07e-01 -9.58e-02 5.89e-01
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS 29 4.15e-01 8.74e-02 5.99e-01
REACTOME HSF1 DEPENDENT TRANSACTIVATION 37 4.15e-01 -7.74e-02 5.99e-01
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15 8 4.15e-01 1.66e-01 5.99e-01
REACTOME DISEASES OF CARBOHYDRATE METABOLISM 31 4.15e-01 -8.45e-02 5.99e-01
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION 26 4.17e-01 -9.20e-02 6.01e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM 34 4.19e-01 -8.01e-02 6.03e-01
REACTOME PTK6 REGULATES CELL CYCLE 6 4.20e-01 -1.90e-01 6.04e-01
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 33 4.20e-01 8.11e-02 6.04e-01
REACTOME NUCLEOTIDE BIOSYNTHESIS 14 4.21e-01 1.24e-01 6.05e-01
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING 12 4.22e-01 1.34e-01 6.06e-01
REACTOME INTERLEUKIN 35 SIGNALLING 12 4.22e-01 -1.34e-01 6.06e-01
REACTOME PECAM1 INTERACTIONS 12 4.25e-01 1.33e-01 6.09e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS 29 4.27e-01 8.53e-02 6.10e-01
REACTOME DNA DAMAGE REVERSAL 8 4.27e-01 -1.62e-01 6.10e-01
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS 11 4.27e-01 1.38e-01 6.10e-01
REACTOME BETA OXIDATION OF PRISTANOYL COA 9 4.28e-01 -1.53e-01 6.10e-01
REACTOME ERBB2 REGULATES CELL MOTILITY 15 4.28e-01 -1.18e-01 6.10e-01
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS 21 4.28e-01 -9.99e-02 6.10e-01
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS 7 4.30e-01 1.72e-01 6.12e-01
REACTOME HEDGEHOG LIGAND BIOGENESIS 64 4.32e-01 -5.68e-02 6.14e-01
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION 30 4.35e-01 -8.24e-02 6.18e-01
REACTOME RAC1 GTPASE CYCLE 172 4.35e-01 -3.45e-02 6.18e-01
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS 6 4.36e-01 -1.84e-01 6.18e-01
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS 5 4.37e-01 2.01e-01 6.20e-01
REACTOME RND1 GTPASE CYCLE 41 4.39e-01 -6.99e-02 6.21e-01
REACTOME EUKARYOTIC TRANSLATION ELONGATION 87 4.39e-01 4.80e-02 6.22e-01
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE 12 4.41e-01 -1.28e-01 6.23e-01
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS 6 4.42e-01 -1.81e-01 6.23e-01
REACTOME FORMATION OF PARAXIAL MESODERM 22 4.42e-01 -9.47e-02 6.23e-01
REACTOME HEME BIOSYNTHESIS 13 4.42e-01 -1.23e-01 6.23e-01
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION 28 4.42e-01 8.39e-02 6.23e-01
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR 21 4.43e-01 -9.67e-02 6.24e-01
REACTOME GLUCAGON TYPE LIGAND RECEPTORS 32 4.44e-01 7.82e-02 6.24e-01
REACTOME THE ACTIVATION OF ARYLSULFATASES 8 4.44e-01 -1.56e-01 6.24e-01
REACTOME INTEGRIN SIGNALING 27 4.45e-01 8.50e-02 6.24e-01
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX 21 4.46e-01 9.62e-02 6.24e-01
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING 13 4.46e-01 1.22e-01 6.24e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION 62 4.46e-01 -5.59e-02 6.24e-01
REACTOME LYSINE CATABOLISM 12 4.47e-01 -1.27e-01 6.24e-01
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY 33 4.47e-01 -7.65e-02 6.24e-01
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX 5 4.48e-01 -1.96e-01 6.24e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI 18 4.48e-01 -1.03e-01 6.24e-01
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES 7 4.48e-01 -1.66e-01 6.24e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS 11 4.48e-01 1.32e-01 6.24e-01
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT 5 4.51e-01 1.95e-01 6.28e-01
REACTOME SEMAPHORIN INTERACTIONS 61 4.52e-01 -5.57e-02 6.28e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE 20 4.54e-01 -9.68e-02 6.31e-01
REACTOME DEGRADATION OF DVL 56 4.56e-01 -5.76e-02 6.33e-01
REACTOME METABOLISM OF STEROID HORMONES 35 4.57e-01 -7.27e-02 6.34e-01
REACTOME ARACHIDONATE PRODUCTION FROM DAG 5 4.58e-01 1.92e-01 6.35e-01
REACTOME PEROXISOMAL PROTEIN IMPORT 62 4.59e-01 -5.44e-02 6.35e-01
REACTOME ORGANIC CATION TRANSPORT 10 4.59e-01 -1.35e-01 6.35e-01
REACTOME RESOLUTION OF ABASIC SITES AP SITES 38 4.61e-01 -6.91e-02 6.38e-01
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY 7 4.61e-01 -1.61e-01 6.38e-01
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING 22 4.62e-01 -9.06e-02 6.38e-01
REACTOME FCERI MEDIATED MAPK ACTIVATION 32 4.63e-01 -7.50e-02 6.38e-01
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION 7 4.63e-01 -1.60e-01 6.38e-01
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA 6 4.63e-01 -1.73e-01 6.38e-01
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS 15 4.65e-01 1.09e-01 6.40e-01
REACTOME OTHER SEMAPHORIN INTERACTIONS 18 4.66e-01 -9.93e-02 6.41e-01
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE 24 4.67e-01 8.58e-02 6.42e-01
REACTOME ERKS ARE INACTIVATED 13 4.68e-01 -1.16e-01 6.42e-01
REACTOME MYOCLONIC EPILEPSY OF LAFORA 9 4.68e-01 -1.40e-01 6.42e-01
REACTOME CA DEPENDENT EVENTS 36 4.69e-01 6.97e-02 6.43e-01
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX 83 4.70e-01 -4.59e-02 6.43e-01
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS 5 4.70e-01 1.87e-01 6.43e-01
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING 14 4.71e-01 -1.11e-01 6.44e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 26 4.72e-01 8.15e-02 6.45e-01
REACTOME COSTIMULATION BY THE CD28 FAMILY 64 4.74e-01 5.17e-02 6.47e-01
REACTOME AQUAPORIN MEDIATED TRANSPORT 51 4.74e-01 -5.79e-02 6.47e-01
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY 33 4.75e-01 7.18e-02 6.47e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION 16 4.78e-01 -1.02e-01 6.51e-01
REACTOME DISINHIBITION OF SNARE FORMATION 5 4.79e-01 -1.83e-01 6.51e-01
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS 21 4.79e-01 -8.91e-02 6.51e-01
REACTOME MRNA CAPPING 28 4.80e-01 -7.72e-02 6.51e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS 62 4.80e-01 -5.19e-02 6.51e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING 89 4.80e-01 -4.33e-02 6.51e-01
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT 6 4.81e-01 -1.66e-01 6.51e-01
REACTOME BASIGIN INTERACTIONS 24 4.81e-01 -8.31e-02 6.51e-01
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS 123 4.81e-01 -3.68e-02 6.51e-01
REACTOME TCR SIGNALING 113 4.82e-01 -3.82e-02 6.52e-01
REACTOME MICRORNA MIRNA BIOGENESIS 25 4.83e-01 -8.11e-02 6.52e-01
REACTOME DEFECTIVE CHSY1 CAUSES TPBS 7 4.83e-01 1.53e-01 6.52e-01
REACTOME PLATELET AGGREGATION PLUG FORMATION 39 4.85e-01 6.46e-02 6.54e-01
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS 5 4.86e-01 -1.80e-01 6.55e-01
REACTOME DSCAM INTERACTIONS 11 4.87e-01 1.21e-01 6.55e-01
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE 5 4.88e-01 -1.79e-01 6.56e-01
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA 17 4.89e-01 -9.70e-02 6.57e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING 24 4.90e-01 -8.14e-02 6.58e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES 8 4.93e-01 -1.40e-01 6.61e-01
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX 31 4.94e-01 -7.10e-02 6.62e-01
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING 46 4.94e-01 -5.83e-02 6.62e-01
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION 5 4.96e-01 -1.76e-01 6.64e-01
REACTOME LIGAND RECEPTOR INTERACTIONS 8 4.96e-01 -1.39e-01 6.64e-01
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS 25 4.98e-01 -7.83e-02 6.65e-01
REACTOME PTK6 EXPRESSION 5 5.00e-01 -1.74e-01 6.67e-01
REACTOME NRAGE SIGNALS DEATH THROUGH JNK 53 5.00e-01 5.35e-02 6.67e-01
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS 24 5.01e-01 -7.94e-02 6.67e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS 28 5.03e-01 -7.31e-02 6.70e-01
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE 7 5.03e-01 -1.46e-01 6.70e-01
REACTOME RHOG GTPASE CYCLE 71 5.04e-01 -4.59e-02 6.70e-01
REACTOME CHAPERONE MEDIATED AUTOPHAGY 20 5.05e-01 8.62e-02 6.70e-01
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION 6 5.06e-01 -1.57e-01 6.71e-01
REACTOME GLUCONEOGENESIS 33 5.06e-01 -6.69e-02 6.71e-01
REACTOME RHOA GTPASE CYCLE 142 5.07e-01 -3.22e-02 6.72e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5 6 5.08e-01 1.56e-01 6.72e-01
REACTOME FGFR2 ALTERNATIVE SPLICING 27 5.09e-01 -7.35e-02 6.73e-01
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION 8 5.09e-01 1.35e-01 6.73e-01
REACTOME HDL ASSEMBLY 8 5.10e-01 -1.35e-01 6.73e-01
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 12 5.11e-01 -1.10e-01 6.74e-01
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 22 5.14e-01 -8.04e-02 6.77e-01
REACTOME RHOQ GTPASE CYCLE 57 5.14e-01 -4.99e-02 6.77e-01
REACTOME SODIUM CALCIUM EXCHANGERS 11 5.14e-01 1.14e-01 6.77e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 31 5.15e-01 6.76e-02 6.78e-01
REACTOME ARACHIDONIC ACID METABOLISM 57 5.18e-01 4.95e-02 6.80e-01
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE 7 5.18e-01 1.41e-01 6.80e-01
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS 16 5.18e-01 -9.33e-02 6.80e-01
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN 45 5.21e-01 -5.53e-02 6.83e-01
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM 6 5.24e-01 1.50e-01 6.87e-01
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE 7 5.25e-01 1.39e-01 6.87e-01
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS 16 5.26e-01 -9.16e-02 6.87e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS 14 5.26e-01 -9.79e-02 6.87e-01
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS 12 5.28e-01 -1.05e-01 6.90e-01
REACTOME REGULATION OF SIGNALING BY NODAL 9 5.29e-01 1.21e-01 6.90e-01
REACTOME INTERLEUKIN 23 SIGNALING 9 5.29e-01 -1.21e-01 6.91e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 122 5.32e-01 -3.28e-02 6.93e-01
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION 22 5.36e-01 -7.63e-02 6.97e-01
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION 42 5.37e-01 -5.51e-02 6.99e-01
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS 7 5.39e-01 -1.34e-01 7.01e-01
REACTOME REGULATION OF IFNA IFNB SIGNALING 23 5.39e-01 7.39e-02 7.01e-01
REACTOME CTLA4 INHIBITORY SIGNALING 21 5.41e-01 7.71e-02 7.02e-01
REACTOME INOSITOL PHOSPHATE METABOLISM 45 5.43e-01 -5.24e-02 7.04e-01
REACTOME DISEASES OF IMMUNE SYSTEM 29 5.44e-01 -6.51e-02 7.05e-01
REACTOME PI3K AKT SIGNALING IN CANCER 103 5.44e-01 -3.46e-02 7.05e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS 21 5.49e-01 -7.55e-02 7.10e-01
REACTOME TRANSPORT OF RCBL WITHIN THE BODY 8 5.49e-01 -1.22e-01 7.10e-01
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL 25 5.50e-01 6.92e-02 7.10e-01
REACTOME SUPPRESSION OF APOPTOSIS 7 5.50e-01 -1.30e-01 7.10e-01
REACTOME GAP JUNCTION ASSEMBLY 36 5.51e-01 -5.74e-02 7.11e-01
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION 27 5.52e-01 -6.62e-02 7.11e-01
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE 19 5.53e-01 -7.86e-02 7.12e-01
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS 14 5.53e-01 9.15e-02 7.12e-01
REACTOME RECYCLING OF EIF2 GDP 7 5.54e-01 -1.29e-01 7.12e-01
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY 24 5.55e-01 -6.96e-02 7.13e-01
REACTOME NTRK2 ACTIVATES RAC1 5 5.55e-01 -1.52e-01 7.13e-01
REACTOME SIGNALING BY FGFR1 49 5.57e-01 4.85e-02 7.13e-01
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA 5 5.57e-01 -1.52e-01 7.13e-01
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES 46 5.57e-01 -5.00e-02 7.13e-01
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1 9 5.61e-01 -1.12e-01 7.19e-01
REACTOME PCP CE PATHWAY 91 5.63e-01 -3.51e-02 7.20e-01
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION 8 5.64e-01 -1.18e-01 7.21e-01
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES 37 5.65e-01 5.47e-02 7.21e-01
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION 5 5.65e-01 -1.49e-01 7.21e-01
REACTOME SIGNALING BY ROBO RECEPTORS 206 5.65e-01 -2.32e-02 7.21e-01
REACTOME SULFIDE OXIDATION TO SULFATE 6 5.67e-01 -1.35e-01 7.22e-01
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND 9 5.70e-01 -1.09e-01 7.26e-01
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED 6 5.73e-01 -1.33e-01 7.28e-01
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 7 5.73e-01 1.23e-01 7.28e-01
REACTOME HSF1 ACTIVATION 29 5.74e-01 -6.04e-02 7.28e-01
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION 5 5.74e-01 -1.45e-01 7.28e-01
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM 21 5.75e-01 7.07e-02 7.29e-01
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE 16 5.77e-01 -8.06e-02 7.31e-01
REACTOME HORMONE LIGAND BINDING RECEPTORS 12 5.77e-01 9.30e-02 7.31e-01
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION 49 5.78e-01 -4.60e-02 7.31e-01
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS 7 5.78e-01 -1.21e-01 7.31e-01
REACTOME PLASMA LIPOPROTEIN CLEARANCE 37 5.80e-01 -5.26e-02 7.33e-01
REACTOME GAP JUNCTION DEGRADATION 12 5.81e-01 -9.19e-02 7.34e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE 20 5.82e-01 -7.11e-02 7.34e-01
REACTOME LAGGING STRAND SYNTHESIS 19 5.83e-01 -7.28e-02 7.34e-01
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA 28 5.86e-01 -5.95e-02 7.38e-01
REACTOME SIGNALING BY FGFR IN DISEASE 62 5.87e-01 -3.99e-02 7.39e-01
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS 170 5.89e-01 2.40e-02 7.41e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS 11 5.90e-01 9.39e-02 7.41e-01
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE 37 5.91e-01 5.10e-02 7.42e-01
REACTOME PROCESSING AND ACTIVATION OF SUMO 10 5.92e-01 -9.77e-02 7.43e-01
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM 11 5.97e-01 -9.22e-02 7.47e-01
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL 14 5.97e-01 -8.17e-02 7.47e-01
REACTOME PLATELET SENSITIZATION BY LDL 17 5.97e-01 -7.41e-02 7.47e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL 15 5.97e-01 7.88e-02 7.47e-01
REACTOME PURINE CATABOLISM 17 5.98e-01 -7.38e-02 7.48e-01
REACTOME PHOSPHORYLATION OF EMI1 6 5.99e-01 -1.24e-01 7.48e-01
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS 10 5.99e-01 9.60e-02 7.48e-01
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL 8 6.01e-01 -1.07e-01 7.49e-01
REACTOME RNA POLYMERASE III CHAIN ELONGATION 18 6.01e-01 -7.12e-02 7.49e-01
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING 29 6.02e-01 -5.59e-02 7.50e-01
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS 9 6.04e-01 9.99e-02 7.51e-01
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9 7 6.04e-01 -1.13e-01 7.51e-01
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION 23 6.06e-01 6.21e-02 7.53e-01
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS 26 6.07e-01 -5.83e-02 7.53e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE 53 6.08e-01 4.08e-02 7.54e-01
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM 13 6.08e-01 -8.21e-02 7.54e-01
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION 5 6.09e-01 1.32e-01 7.54e-01
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION 11 6.10e-01 -8.88e-02 7.55e-01
REACTOME G PROTEIN ACTIVATION 24 6.11e-01 -6.01e-02 7.55e-01
REACTOME METALLOTHIONEINS BIND METALS 11 6.11e-01 8.86e-02 7.55e-01
REACTOME HYALURONAN METABOLISM 17 6.12e-01 -7.11e-02 7.56e-01
REACTOME SYNTHESIS OF GDP MANNOSE 5 6.14e-01 -1.30e-01 7.57e-01
REACTOME IRS ACTIVATION 5 6.14e-01 1.30e-01 7.57e-01
REACTOME CELL CELL COMMUNICATION 126 6.15e-01 2.59e-02 7.57e-01
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN 32 6.15e-01 -5.14e-02 7.57e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS 14 6.18e-01 -7.70e-02 7.60e-01
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 58 6.18e-01 -3.79e-02 7.60e-01
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION 42 6.21e-01 -4.41e-02 7.62e-01
REACTOME RHOBTB3 ATPASE CYCLE 8 6.22e-01 -1.01e-01 7.63e-01
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 161 6.23e-01 -2.24e-02 7.64e-01
REACTOME LONG TERM POTENTIATION 22 6.26e-01 6.00e-02 7.67e-01
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 25 6.26e-01 -5.63e-02 7.67e-01
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY 10 6.27e-01 -8.89e-02 7.67e-01
REACTOME GPER1 SIGNALING 45 6.29e-01 -4.16e-02 7.69e-01
REACTOME OPIOID SIGNALLING 89 6.32e-01 -2.93e-02 7.73e-01
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS 21 6.35e-01 5.98e-02 7.74e-01
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION 6 6.36e-01 -1.12e-01 7.74e-01
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK 111 6.36e-01 -2.60e-02 7.74e-01
REACTOME PHASE 2 PLATEAU PHASE 14 6.36e-01 7.31e-02 7.74e-01
REACTOME THYROXINE BIOSYNTHESIS 10 6.38e-01 -8.60e-02 7.76e-01
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE 69 6.39e-01 -3.27e-02 7.77e-01
REACTOME TRANSLESION SYNTHESIS BY POLK 17 6.41e-01 -6.54e-02 7.79e-01
REACTOME SEROTONIN RECEPTORS 11 6.42e-01 -8.09e-02 7.80e-01
REACTOME DOWNREGULATION OF ERBB4 SIGNALING 9 6.44e-01 -8.89e-02 7.80e-01
REACTOME AZATHIOPRINE ADME 22 6.44e-01 -5.69e-02 7.80e-01
REACTOME INSULIN PROCESSING 24 6.44e-01 -5.45e-02 7.80e-01
REACTOME NERVOUS SYSTEM DEVELOPMENT 552 6.44e-01 -1.15e-02 7.80e-01
REACTOME SIGNALING BY FGFR4 40 6.45e-01 4.20e-02 7.81e-01
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA 14 6.46e-01 7.08e-02 7.81e-01
REACTOME MYOGENESIS 29 6.47e-01 -4.91e-02 7.82e-01
REACTOME O LINKED GLYCOSYLATION OF MUCINS 61 6.48e-01 3.38e-02 7.82e-01
REACTOME UREA CYCLE 9 6.48e-01 8.78e-02 7.82e-01
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS 19 6.50e-01 -6.01e-02 7.84e-01
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT 23 6.52e-01 -5.44e-02 7.85e-01
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION 7 6.52e-01 9.84e-02 7.85e-01
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY 94 6.55e-01 2.67e-02 7.88e-01
REACTOME SPRY REGULATION OF FGF SIGNALING 16 6.57e-01 -6.42e-02 7.89e-01
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE 17 6.57e-01 6.22e-02 7.89e-01
REACTOME TELOMERE EXTENSION BY TELOMERASE 22 6.59e-01 -5.43e-02 7.91e-01
REACTOME BILE ACID AND BILE SALT METABOLISM 45 6.59e-01 3.80e-02 7.91e-01
REACTOME PROLONGED ERK ACTIVATION EVENTS 14 6.60e-01 -6.78e-02 7.91e-01
REACTOME RSK ACTIVATION 5 6.61e-01 -1.13e-01 7.92e-01
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 12 6.65e-01 -7.22e-02 7.96e-01
REACTOME DNA REPLICATION INITIATION 7 6.70e-01 -9.30e-02 8.01e-01
REACTOME NETRIN 1 SIGNALING 49 6.72e-01 3.49e-02 8.03e-01
REACTOME EGFR TRANSACTIVATION BY GASTRIN 9 6.73e-01 -8.12e-02 8.04e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K 6 6.74e-01 -9.93e-02 8.04e-01
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA 7 6.77e-01 9.10e-02 8.07e-01
REACTOME TRANSPORT AND SYNTHESIS OF PAPS 6 6.78e-01 -9.79e-02 8.08e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS 16 6.80e-01 5.95e-02 8.10e-01
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING 6 6.84e-01 9.60e-02 8.13e-01
REACTOME RETINOID CYCLE DISEASE EVENTS 11 6.84e-01 7.08e-02 8.13e-01
REACTOME IRS MEDIATED SIGNALLING 47 6.85e-01 3.42e-02 8.13e-01
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS 42 6.85e-01 -3.62e-02 8.13e-01
REACTOME DERMATAN SULFATE BIOSYNTHESIS 10 6.85e-01 -7.40e-02 8.13e-01
REACTOME G ALPHA Z SIGNALLING EVENTS 48 6.86e-01 -3.37e-02 8.13e-01
REACTOME DAG AND IP3 SIGNALING 40 6.86e-01 3.69e-02 8.13e-01
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS 27 6.87e-01 -4.48e-02 8.14e-01
REACTOME MTORC1 MEDIATED SIGNALLING 23 6.88e-01 -4.83e-02 8.14e-01
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS 63 6.89e-01 -2.91e-02 8.15e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS 185 6.90e-01 -1.70e-02 8.15e-01
REACTOME HIV ELONGATION ARREST AND RECOVERY 33 6.91e-01 -3.99e-02 8.16e-01
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT 99 6.91e-01 -2.31e-02 8.16e-01
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS 8 6.92e-01 -8.08e-02 8.16e-01
REACTOME METABOLISM OF PORPHYRINS 26 6.93e-01 4.47e-02 8.16e-01
REACTOME GLYCOGEN STORAGE DISEASES 15 6.93e-01 -5.88e-02 8.16e-01
REACTOME PHENYLALANINE METABOLISM 6 6.96e-01 -9.20e-02 8.18e-01
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA 5 6.97e-01 -1.01e-01 8.18e-01
REACTOME G ALPHA Q SIGNALLING EVENTS 206 6.97e-01 1.57e-02 8.18e-01
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET 8 6.98e-01 7.93e-02 8.18e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 24 6.98e-01 4.57e-02 8.18e-01
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION 13 6.98e-01 6.21e-02 8.18e-01
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION 19 6.99e-01 5.13e-02 8.18e-01
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS 10 6.99e-01 7.06e-02 8.18e-01
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION 6 7.01e-01 -9.05e-02 8.20e-01
REACTOME CHL1 INTERACTIONS 9 7.02e-01 -7.37e-02 8.20e-01
REACTOME ESTROGEN BIOSYNTHESIS 6 7.03e-01 -9.00e-02 8.21e-01
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY 25 7.05e-01 -4.37e-02 8.22e-01
REACTOME MRNA EDITING 10 7.05e-01 -6.91e-02 8.22e-01
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 41 7.07e-01 -3.39e-02 8.24e-01
REACTOME RELAXIN RECEPTORS 8 7.07e-01 -7.66e-02 8.24e-01
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1 6 7.09e-01 8.79e-02 8.25e-01
REACTOME G ALPHA 12 13 SIGNALLING EVENTS 74 7.14e-01 2.46e-02 8.29e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS 27 7.14e-01 -4.07e-02 8.29e-01
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING 13 7.14e-01 -5.87e-02 8.29e-01
REACTOME GLYCOGEN METABOLISM 22 7.16e-01 -4.47e-02 8.30e-01
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE 5 7.16e-01 9.38e-02 8.30e-01
REACTOME NEUROTRANSMITTER RELEASE CYCLE 48 7.17e-01 3.03e-02 8.30e-01
REACTOME SIGNALING BY NOTCH3 48 7.17e-01 -3.02e-02 8.30e-01
REACTOME REGULATION OF INSULIN SECRETION 77 7.24e-01 2.33e-02 8.37e-01
REACTOME PERK REGULATES GENE EXPRESSION 31 7.24e-01 -3.66e-02 8.37e-01
REACTOME ZINC TRANSPORTERS 15 7.25e-01 -5.25e-02 8.37e-01
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL 122 7.26e-01 1.83e-02 8.39e-01
REACTOME NEF AND SIGNAL TRANSDUCTION 8 7.29e-01 -7.08e-02 8.41e-01
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY 15 7.31e-01 -5.13e-02 8.43e-01
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE 49 7.32e-01 2.83e-02 8.44e-01
REACTOME SIGNALING BY WNT IN CANCER 32 7.34e-01 3.47e-02 8.45e-01
REACTOME SCAVENGING BY CLASS A RECEPTORS 19 7.38e-01 4.44e-02 8.49e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS 9 7.42e-01 6.33e-02 8.53e-01
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION 18 7.42e-01 -4.47e-02 8.53e-01
REACTOME ANDROGEN BIOSYNTHESIS 11 7.43e-01 -5.72e-02 8.53e-01
REACTOME FRUCTOSE METABOLISM 7 7.46e-01 7.08e-02 8.56e-01
REACTOME SIGNALING BY FGFR2 IIIA TM 19 7.48e-01 4.26e-02 8.57e-01
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY 46 7.50e-01 -2.71e-02 8.60e-01
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 27 7.52e-01 -3.52e-02 8.60e-01
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR 11 7.52e-01 -5.50e-02 8.60e-01
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS 11 7.52e-01 -5.50e-02 8.60e-01
REACTOME RA BIOSYNTHESIS PATHWAY 22 7.56e-01 -3.83e-02 8.64e-01
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB 19 7.59e-01 4.06e-02 8.67e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE 11 7.60e-01 -5.31e-02 8.68e-01
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI 5 7.62e-01 -7.82e-02 8.69e-01
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM 6 7.64e-01 7.07e-02 8.71e-01
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR 8 7.66e-01 -6.09e-02 8.72e-01
REACTOME RRNA PROCESSING IN THE MITOCHONDRION 9 7.66e-01 -5.73e-02 8.72e-01
REACTOME RIBAVIRIN ADME 11 7.67e-01 -5.15e-02 8.72e-01
REACTOME MET RECEPTOR ACTIVATION 6 7.68e-01 -6.96e-02 8.72e-01
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE 17 7.70e-01 4.09e-02 8.75e-01
REACTOME INTEGRATION OF ENERGY METABOLISM 105 7.71e-01 -1.64e-02 8.75e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS 8 7.72e-01 -5.93e-02 8.75e-01
REACTOME GLYCOSAMINOGLYCAN METABOLISM 118 7.72e-01 -1.54e-02 8.75e-01
REACTOME COBALAMIN CBL METABOLISM 7 7.72e-01 -6.31e-02 8.75e-01
REACTOME INACTIVATION OF CDC42 AND RAC1 8 7.75e-01 5.85e-02 8.76e-01
REACTOME SIGNAL ATTENUATION 10 7.75e-01 -5.22e-02 8.76e-01
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA 5 7.78e-01 -7.27e-02 8.79e-01
REACTOME KERATAN SULFATE DEGRADATION 13 7.82e-01 4.44e-02 8.83e-01
REACTOME PYRIMIDINE CATABOLISM 12 7.83e-01 -4.59e-02 8.84e-01
REACTOME TRP CHANNELS 27 7.84e-01 3.05e-02 8.84e-01
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D 8 7.86e-01 5.54e-02 8.86e-01
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION 21 7.87e-01 -3.41e-02 8.86e-01
REACTOME CHYLOMICRON CLEARANCE 5 7.89e-01 6.92e-02 8.87e-01
REACTOME NEF MEDIATED CD8 DOWN REGULATION 7 7.89e-01 5.85e-02 8.87e-01
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S 53 7.92e-01 2.10e-02 8.90e-01
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS 8 7.94e-01 -5.34e-02 8.91e-01
REACTOME DISSOLUTION OF FIBRIN CLOT 13 7.96e-01 4.14e-02 8.92e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL 24 7.96e-01 3.05e-02 8.92e-01
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING 17 7.96e-01 3.62e-02 8.92e-01
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM 7 8.00e-01 5.52e-02 8.96e-01
REACTOME PHASE II CONJUGATION OF COMPOUNDS 102 8.02e-01 1.44e-02 8.97e-01
REACTOME ALPHA OXIDATION OF PHYTANATE 6 8.04e-01 -5.86e-02 8.99e-01
REACTOME EPHRIN SIGNALING 17 8.05e-01 -3.45e-02 9.00e-01
REACTOME ABC TRANSPORTER DISORDERS 76 8.07e-01 -1.62e-02 9.02e-01
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS 9 8.09e-01 4.66e-02 9.03e-01
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS 36 8.11e-01 -2.31e-02 9.03e-01
REACTOME SIGNALING BY HIPPO 19 8.11e-01 -3.17e-02 9.03e-01
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE 7 8.11e-01 5.22e-02 9.03e-01
REACTOME FOLDING OF ACTIN BY CCT TRIC 10 8.11e-01 -4.37e-02 9.03e-01
REACTOME METAL ION SLC TRANSPORTERS 23 8.12e-01 -2.87e-02 9.03e-01
REACTOME SMOOTH MUSCLE CONTRACTION 43 8.14e-01 -2.08e-02 9.05e-01
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY 12 8.16e-01 3.88e-02 9.07e-01
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION 10 8.17e-01 -4.23e-02 9.07e-01
REACTOME GDP FUCOSE BIOSYNTHESIS 6 8.17e-01 -5.45e-02 9.07e-01
REACTOME CDC42 GTPASE CYCLE 144 8.18e-01 1.11e-02 9.07e-01
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND 14 8.20e-01 -3.51e-02 9.08e-01
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE 6 8.22e-01 5.30e-02 9.10e-01
REACTOME SIGNALING BY MST1 5 8.25e-01 5.70e-02 9.13e-01
REACTOME SIGNALING BY NODAL 20 8.25e-01 2.85e-02 9.13e-01
REACTOME SPERM MOTILITY AND TAXES 9 8.26e-01 4.23e-02 9.13e-01
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR 19 8.30e-01 2.85e-02 9.16e-01
REACTOME SIALIC ACID METABOLISM 33 8.33e-01 2.12e-02 9.18e-01
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER 15 8.34e-01 -3.13e-02 9.18e-01
REACTOME RHOH GTPASE CYCLE 37 8.34e-01 1.99e-02 9.18e-01
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1 5 8.34e-01 -5.40e-02 9.18e-01
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION 7 8.35e-01 4.56e-02 9.18e-01
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS 11 8.37e-01 3.57e-02 9.21e-01
REACTOME G2 PHASE 5 8.40e-01 -5.20e-02 9.24e-01
REACTOME NADE MODULATES DEATH SIGNALLING 5 8.41e-01 -5.17e-02 9.24e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS 26 8.42e-01 -2.26e-02 9.24e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING 6 8.43e-01 -4.68e-02 9.24e-01
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS 17 8.44e-01 -2.76e-02 9.24e-01
REACTOME ELASTIC FIBRE FORMATION 44 8.44e-01 1.71e-02 9.24e-01
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION 19 8.45e-01 2.60e-02 9.24e-01
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS 5 8.45e-01 5.05e-02 9.24e-01
REACTOME CALCITONIN LIKE LIGAND RECEPTORS 10 8.45e-01 -3.57e-02 9.24e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER 77 8.46e-01 1.28e-02 9.24e-01
REACTOME ACYL CHAIN REMODELING OF CL 5 8.46e-01 5.01e-02 9.24e-01
REACTOME EUKARYOTIC TRANSLATION INITIATION 110 8.48e-01 1.06e-02 9.25e-01
REACTOME G PROTEIN MEDIATED EVENTS 53 8.49e-01 -1.51e-02 9.26e-01
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN 13 8.50e-01 3.03e-02 9.26e-01
REACTOME SYNTHESIS OF KETONE BODIES 8 8.50e-01 -3.85e-02 9.26e-01
REACTOME AMINE LIGAND BINDING RECEPTORS 40 8.51e-01 1.71e-02 9.26e-01
REACTOME MITOCHONDRIAL UNCOUPLING 5 8.52e-01 -4.82e-02 9.26e-01
REACTOME PTK6 PROMOTES HIF1A STABILIZATION 6 8.54e-01 4.35e-02 9.28e-01
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION 12 8.54e-01 3.06e-02 9.28e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK 17 8.55e-01 -2.56e-02 9.28e-01
REACTOME VITAMIN B1 THIAMIN METABOLISM 5 8.57e-01 -4.65e-02 9.29e-01
REACTOME SIGNALING BY FGFR2 72 8.57e-01 -1.22e-02 9.29e-01
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND 21 8.58e-01 2.26e-02 9.29e-01
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM 45 8.58e-01 -1.54e-02 9.29e-01
REACTOME CD28 DEPENDENT VAV1 PATHWAY 11 8.59e-01 -3.09e-02 9.29e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING 11 8.63e-01 -3.00e-02 9.33e-01
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS 9 8.64e-01 -3.29e-02 9.33e-01
REACTOME MTOR SIGNALLING 40 8.64e-01 -1.56e-02 9.33e-01
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY 14 8.67e-01 2.58e-02 9.36e-01
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS 11 8.68e-01 2.90e-02 9.36e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION 27 8.69e-01 1.83e-02 9.37e-01
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE 30 8.74e-01 -1.68e-02 9.41e-01
REACTOME PASSIVE TRANSPORT BY AQUAPORINS 13 8.77e-01 -2.48e-02 9.43e-01
REACTOME IRAK4 DEFICIENCY TLR2 4 17 8.77e-01 -2.16e-02 9.43e-01
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION 9 8.77e-01 2.97e-02 9.43e-01
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 24 8.78e-01 1.80e-02 9.43e-01
REACTOME MET INTERACTS WITH TNS PROTEINS 5 8.85e-01 -3.75e-02 9.49e-01
REACTOME G2 M DNA REPLICATION CHECKPOINT 5 8.86e-01 -3.70e-02 9.49e-01
REACTOME PROCESSING OF SMDT1 16 8.86e-01 -2.06e-02 9.49e-01
REACTOME SELENOAMINO ACID METABOLISM 108 8.87e-01 7.90e-03 9.49e-01
REACTOME REGULATION OF KIT SIGNALING 16 8.88e-01 -2.04e-02 9.49e-01
REACTOME SYNTHESIS OF PA 38 8.88e-01 -1.32e-02 9.49e-01
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES 353 8.88e-01 -4.36e-03 9.49e-01
REACTOME SODIUM PROTON EXCHANGERS 7 8.90e-01 3.02e-02 9.51e-01
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY 29 8.90e-01 1.48e-02 9.51e-01
REACTOME NONSENSE MEDIATED DECAY NMD 107 8.93e-01 7.51e-03 9.53e-01
REACTOME NEUROTRANSMITTER CLEARANCE 9 8.93e-01 -2.58e-02 9.53e-01
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS 7 8.94e-01 2.90e-02 9.53e-01
REACTOME PINK1 PRKN MEDIATED MITOPHAGY 22 8.95e-01 -1.62e-02 9.53e-01
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE 30 8.96e-01 1.38e-02 9.53e-01
REACTOME EARLY SARS COV 2 INFECTION EVENTS 34 8.97e-01 -1.29e-02 9.53e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM 39 8.98e-01 -1.19e-02 9.53e-01
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION 5 8.98e-01 -3.31e-02 9.53e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN 7 8.98e-01 2.79e-02 9.53e-01
REACTOME SIGNALING BY FGFR 85 8.99e-01 7.94e-03 9.53e-01
REACTOME MINERALOCORTICOID BIOSYNTHESIS 6 8.99e-01 2.98e-02 9.53e-01
REACTOME PROLACTIN RECEPTOR SIGNALING 15 8.99e-01 -1.88e-02 9.53e-01
REACTOME RESPONSE TO METAL IONS 14 9.00e-01 -1.94e-02 9.53e-01
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE 16 9.01e-01 -1.79e-02 9.53e-01
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION 20 9.01e-01 1.60e-02 9.53e-01
REACTOME NEUROFASCIN INTERACTIONS 6 9.02e-01 2.92e-02 9.53e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING 14 9.04e-01 1.86e-02 9.54e-01
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS 18 9.04e-01 -1.64e-02 9.54e-01
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING 5 9.08e-01 3.00e-02 9.57e-01
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL 8 9.09e-01 -2.33e-02 9.58e-01
REACTOME HDL CLEARANCE 5 9.11e-01 -2.88e-02 9.60e-01
REACTOME FRUCTOSE CATABOLISM 5 9.12e-01 2.84e-02 9.60e-01
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM 23 9.14e-01 -1.30e-02 9.61e-01
REACTOME ACTIVATION OF RAC1 12 9.15e-01 -1.79e-02 9.61e-01
REACTOME VXPX CARGO TARGETING TO CILIUM 20 9.15e-01 -1.38e-02 9.61e-01
REACTOME ENDOSOMAL VACUOLAR PATHWAY 11 9.16e-01 1.84e-02 9.61e-01
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS 20 9.16e-01 1.36e-02 9.61e-01
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION 32 9.18e-01 -1.05e-02 9.63e-01
REACTOME SIGNALING BY PDGF 57 9.20e-01 7.67e-03 9.63e-01
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS 17 9.20e-01 1.40e-02 9.63e-01
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION 19 9.22e-01 1.30e-02 9.63e-01
REACTOME SULFUR AMINO ACID METABOLISM 27 9.22e-01 1.08e-02 9.63e-01
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES 6 9.22e-01 2.30e-02 9.63e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS 34 9.23e-01 9.61e-03 9.63e-01
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS 7 9.23e-01 -2.11e-02 9.63e-01
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A 5 9.23e-01 2.49e-02 9.63e-01
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY 16 9.25e-01 1.37e-02 9.64e-01
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION 8 9.26e-01 1.90e-02 9.64e-01
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS 10 9.26e-01 1.70e-02 9.64e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN 5 9.28e-01 -2.35e-02 9.65e-01
REACTOME RUNX2 REGULATES BONE DEVELOPMENT 29 9.28e-01 -9.72e-03 9.65e-01
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT 7 9.28e-01 1.96e-02 9.65e-01
REACTOME NEF MEDIATED CD4 DOWN REGULATION 9 9.29e-01 1.72e-02 9.65e-01
REACTOME INTERLEUKIN 37 SIGNALING 20 9.30e-01 1.14e-02 9.65e-01
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES 6 9.30e-01 -2.07e-02 9.65e-01
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN 11 9.36e-01 -1.40e-02 9.70e-01
REACTOME VLDL ASSEMBLY 5 9.37e-01 2.04e-02 9.70e-01
REACTOME PLATELET HOMEOSTASIS 85 9.38e-01 -4.91e-03 9.70e-01
REACTOME SIGNALING BY FGFR3 39 9.38e-01 -7.24e-03 9.70e-01
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS 6 9.39e-01 -1.81e-02 9.71e-01
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX 15 9.41e-01 1.10e-02 9.72e-01
REACTOME GERM LAYER FORMATION AT GASTRULATION 17 9.42e-01 1.02e-02 9.72e-01
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA 5 9.43e-01 -1.85e-02 9.72e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN 13 9.43e-01 -1.15e-02 9.72e-01
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING 13 9.45e-01 1.11e-02 9.74e-01
REACTOME METHYLATION 14 9.47e-01 -1.03e-02 9.75e-01
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 105 9.47e-01 3.75e-03 9.75e-01
REACTOME RECYCLING OF BILE ACIDS AND SALTS 18 9.47e-01 -9.00e-03 9.75e-01
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS 10 9.48e-01 -1.19e-02 9.75e-01
REACTOME LINOLEIC ACID LA METABOLISM 7 9.49e-01 1.41e-02 9.75e-01
REACTOME CS DS DEGRADATION 12 9.49e-01 1.07e-02 9.75e-01
REACTOME PHYSIOLOGICAL FACTORS 14 9.50e-01 -9.65e-03 9.75e-01
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK 28 9.51e-01 6.71e-03 9.75e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING 25 9.51e-01 7.04e-03 9.75e-01
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN 19 9.52e-01 7.90e-03 9.76e-01
REACTOME MASTL FACILITATES MITOTIC PROGRESSION 10 9.54e-01 1.05e-02 9.76e-01
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE 17 9.54e-01 -8.04e-03 9.76e-01
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS 9 9.55e-01 -1.09e-02 9.76e-01
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE 21 9.57e-01 -6.75e-03 9.78e-01
REACTOME KETONE BODY METABOLISM 9 9.58e-01 1.01e-02 9.78e-01
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD 5 9.58e-01 1.35e-02 9.78e-01
REACTOME INTERLEUKIN 18 SIGNALING 8 9.59e-01 1.05e-02 9.78e-01
REACTOME SYNTHESIS OF PE 13 9.60e-01 8.11e-03 9.78e-01
REACTOME VLDL CLEARANCE 6 9.61e-01 -1.15e-02 9.79e-01
REACTOME SCAVENGING OF HEME FROM PLASMA 13 9.62e-01 -7.72e-03 9.79e-01
REACTOME THE PHOTOTRANSDUCTION CASCADE 32 9.65e-01 4.44e-03 9.82e-01
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION 27 9.69e-01 -4.35e-03 9.85e-01
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM 12 9.70e-01 6.37e-03 9.85e-01
REACTOME METABOLISM OF POLYAMINES 56 9.70e-01 2.87e-03 9.85e-01
REACTOME MRNA EDITING C TO U CONVERSION 8 9.70e-01 -7.57e-03 9.85e-01
REACTOME DOPAMINE RECEPTORS 5 9.72e-01 9.11e-03 9.85e-01
REACTOME NUCLEAR SIGNALING BY ERBB4 32 9.73e-01 -3.50e-03 9.85e-01
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION 13 9.73e-01 -5.45e-03 9.85e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4 15 9.74e-01 4.94e-03 9.85e-01
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS 23 9.74e-01 3.94e-03 9.85e-01
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS 19 9.74e-01 4.24e-03 9.85e-01
REACTOME SYNTHESIS OF PI 5 9.75e-01 7.98e-03 9.86e-01
REACTOME FREE FATTY ACID RECEPTORS 5 9.79e-01 -6.80e-03 9.88e-01
REACTOME LIPOPHAGY 9 9.79e-01 4.97e-03 9.88e-01
REACTOME JOSEPHIN DOMAIN DUBS 11 9.84e-01 -3.56e-03 9.92e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS 36 9.84e-01 1.91e-03 9.92e-01
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION 6 9.88e-01 -3.41e-03 9.95e-01
REACTOME L1CAM INTERACTIONS 112 9.89e-01 7.87e-04 9.95e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R 52 9.89e-01 1.12e-03 9.95e-01
REACTOME ADHERENS JUNCTIONS INTERACTIONS 33 9.90e-01 -1.27e-03 9.95e-01
REACTOME SIGNALING BY BMP 27 9.90e-01 1.36e-03 9.95e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS 16 9.91e-01 -1.63e-03 9.95e-01
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE 15 9.93e-01 -1.39e-03 9.96e-01
REACTOME SIGNALING BY MET 78 9.94e-01 4.75e-04 9.97e-01
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT 23 9.97e-01 5.10e-04 9.99e-01
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION 8 9.98e-01 5.57e-04 9.99e-01
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS 10 9.99e-01 3.18e-04 9.99e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 13 9.99e-01 2.59e-04 9.99e-01
REACTOME TRYPTOPHAN CATABOLISM 14 1.00e+00 9.09e-05 1.00e+00



Detailed Gene set reports



REACTOME_SENSORY_PERCEPTION

REACTOME_SENSORY_PERCEPTION
1581
set REACTOME_SENSORY_PERCEPTION
setSize 555
pANOVA 7.47e-32
s.dist 0.291
p.adjustANOVA 1.23e-28



Top enriched genes

Top 20 genes
GeneID Gene Rank
OR2T3 10981
OR56B4 10966
OR51G2 10949
OR2S2 10925
OR51D1 10910
OR10S1 10907
OR9K2 10881
OR5AU1 10843
OR4D6 10839
OR8B4 10825
OR1A2 10813
OR5T1 10799
OR4D11 10774
OR10J5 10749
OR56A5 10683
OR3A3 10681
OR56A1 10677
OR10C1 10674
OR8A1 10654
OR10J3 10644

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OR2T3 10981.0
OR56B4 10966.0
OR51G2 10949.0
OR2S2 10925.0
OR51D1 10910.0
OR10S1 10907.0
OR9K2 10881.0
OR5AU1 10843.0
OR4D6 10839.0
OR8B4 10825.0
OR1A2 10813.0
OR5T1 10799.0
OR4D11 10774.0
OR10J5 10749.0
OR56A5 10683.0
OR3A3 10681.0
OR56A1 10677.0
OR10C1 10674.0
OR8A1 10654.0
OR10J3 10644.0
OR6K3 10631.0
OR56A3 10616.0
OR4A47 10606.0
AKR1B10 10605.0
APOA4 10601.0
TAS1R3 10600.0
OR10H2 10579.0
OR8G5 10563.0
OR10T2 10560.0
TAS2R38 10554.0
STRA6 10549.0
GUCA1A 10525.0
OR12D2 10505.0
RTP2 10487.0
AKR1C1 10408.0
OR5A1 10403.0
OR52R1 10369.0
OR8G1 10367.0
OR10J1 10345.0
OR4C16 10301.0
OR9A4 10276.0
OR52I2 10270.0
OR10H3 10263.0
OR6Y1 10233.0
OR14C36 10210.0
OR11L1 10194.0
CNGB1 10176.0
OR3A1 10158.0
OR2C1 10133.0
OR5B2 10128.0
OR10X1 10112.0
TAS2R39 10103.0
OR13F1 10096.0
OR10G4 10094.0
CNGA4 10088.0
OR10K1 10078.0
OR6C6 10073.0
OR1A1 10072.0
OR51S1 10045.0
OR11H6 10042.0
OR5V1 10033.0
TAS1R1 10026.0
OR2M3 10016.0
USH1C 9990.0
OR1G1 9976.0
AKR1C4 9946.0
OR2L5 9940.0
OR13D1 9923.0
OR2T6 9915.0
RBP3 9897.0
CTBP2 9851.0
OR9Q1 9826.0
OR2AT4 9812.0
OR6X1 9809.0
OR4D10 9793.0
OR10K2 9777.0
TTR 9756.0
OR51G1 9753.0
OR10V1 9740.0
BSN 9704.0
OR10G9 9691.0
APOC3 9690.0
GNB3 9683.0
OR6C65 9681.0
RTP1 9662.0
OR4D9 9656.0
OR13C2 9649.0
TRPM5 9613.0
PLB1 9605.0
OR4S1 9582.0
OR52E4 9576.0
OR2W1 9568.0
HSD17B6 9556.0
OR6C1 9548.0
OR6B2 9526.0
OR51A7 9524.0
OR2AP1 9508.0
RHO 9487.0
OR2H2 9481.0
OTOG 9462.0
OR4K2 9458.0
OR10W1 9451.0
OR2M4 9446.0
OR11A1 9441.0
OR6C76 9415.0
OR52N2 9409.0
OR8S1 9378.0
OR5K2 9376.0
OR5A2 9374.0
OR6C74 9369.0
RBP2 9350.0
OR10AD1 9338.0
APOA2 9329.0
OR5K3 9318.0
GRK7 9298.0
OR1I1 9296.0
OR4D2 9281.0
CALHM1 9270.0
OR51B2 9269.0
OR10A4 9265.5
GRXCR2 9263.0
OR2T27 9192.0
LHFPL5 9165.0
OR2A5 9145.0
OR2B11 9116.0
OR5H15 9086.0
CABP2 9083.0
TMC2 9081.0
LRRC52 9054.0
TAS2R3 9031.0
OR1F1 9011.0
OR4K17 8992.0
OR5H2 8946.0
OR10A2 8944.0
OR1M1 8930.0
OR6C4 8916.0
OR52M1 8914.0
OR2AG1 8873.0
OR4B1 8781.0
OR7G2 8748.0
OR8J3 8745.0
OR2V2 8741.0
OR4C45 8722.0
KCNQ4 8711.0
OR14J1 8685.0
OR2Y1 8678.0
OR56A4 8672.0
OR1E1 8661.0
OR8B2 8646.0
OR2AK2 8619.0
OR2F2 8599.0
TRPM4 8536.0
ATP2B2 8502.0
OR52A5 8496.0
HSPG2 8495.0
OR7A5 8490.0
OR4L1 8478.0
OR4N2 8459.0
OR5T2 8405.0
OR4D1 8387.0
OR5AS1 8365.0
OR4K1 8321.0
OR13J1 8281.0
OR2D3 8267.0
OR1L3 8206.0
CIB2 8193.0
OR2T11 8168.0
TAS2R31 8166.0
ESPNL 8154.0
OR12D3 8153.0
OR10G3 8147.0
OR2A2 8144.0
OR2L3 8139.0
OR5AC2 8130.0
OR5AK2 8100.0
OR14A16 8048.0
OR7E24 8047.0
ANO2 8038.0
GNG13 8027.0
CHRNA9 8007.0
ABCA4 7979.0
OR10A6 7959.0
OR52N1 7950.0
OR51A2 7949.0
OR51E1 7910.0
KCNMB1 7904.0
OR2V1 7859.0
OR2B3 7834.0
OR52B6 7814.0
TAS2R7 7808.0
OR6C2 7772.0
MYO15A 7756.0
OR2M5 7628.0
OR2G2 7615.0
OR5M11 7609.0
SLC24A1 7536.0
OR2T12 7535.0
APOC2 7534.0
OR2Z1 7509.0
OR2T33 7507.0
EPS8L2 7431.0
CACNA1D 7427.0
OR7C1 7426.0
OR13C8 7419.0
OR4F15 7396.0
KCNMA1 7390.0
OR10AG1 7379.0
LRP1 7369.0
OR10H4 7309.0
RPE65 7287.0
OR1L1 7279.0
OR9A2 7196.0
OR10H1 7180.0
OR2F1 7075.0
TAS2R10 7050.0
SLC17A8 7009.0
OR5P2 6955.0
OR6A2 6915.0
OTOF 6901.0
CACNA2D2 6882.0
GPC1 6866.0
OR4N5 6854.0
OR6C70 6830.0
OR4K14 6829.0
OR10A7 6815.0
OR10G8 6703.0
OR1D2 6680.0
OR6M1 6664.0
REEP1 6628.0
GRM4 6550.0
OR6N1 6546.0
OR5K1 6534.0
SCN4B 6518.0
RCVRN 6486.0
OR13C3 6442.0
GPC6 6397.0
OR11G2 6390.0
SDC2 6383.0
OR10G2 6357.0
OR51B5 6316.0
AGRN 6226.0
TAS2R16 6203.0
OR5M10 6177.0
PDE6B 6133.0
OR13C4 6121.0
EPB41L1 6087.0
OR6Q1 6085.0
GRK1 6084.0
OR52E8 6062.0
TAS1R2 6061.0
OR51Q1 6034.0
OR8H1 6024.0
APOE 5875.0
OR6N2 5870.0
OR2G3 5834.0
OR51F2 5721.0
OR13A1 5679.0
CDH23 5677.0
GPIHBP1 5640.0
OR5L1 5576.0
SDR9C7 5548.0
OR52I1 5534.0
SCNN1D 5522.0
GPC2 5494.0
MYO7A 5480.0
OR51E2 5438.0
ITPR3 5421.0
OR10G7 5366.0
OR7A17 5356.0
RDH16 5342.0
MYO3A 5330.0
ATP2B1 5320.0
OR2G6 5304.0
CLPS 5238.0
OR7A10 5229.0
GNAT3 5218.0
GRXCR1 5216.0
OR1C1 5211.0
CACNB2 5184.0
KCNJ2 5147.0
TAS2R40 5131.0
SCN3A 5052.0
XIRP2 5050.0
OR6K2 5046.0
OR8D1 4983.0
SDC1 4970.0
SDC4 4918.0
RDH12 4862.0
OR5B3 4814.0
OR56B1 4726.0
OR4A5 4584.0
TMIE 4564.0
APOM 4526.0
OR6V1 4523.0
MYH9 4460.0
OR51M1 4446.0
OR51V1 4426.0
OR51L1 4414.0
EPS8 4395.0
OR5W2 4291.0
RETSAT 4288.0
OR8D4 4282.0
OR6K6 4257.0
TAS2R5 4218.0
EBF1 4215.0
OR4K15 4102.0
OR8J1 4041.0
ESPN 4008.0
OR52L1 3824.0
OR2H1 3821.0
OR8I2 3769.0
OR2J2 3748.0
OR1L6 3743.0
OR10H5 3729.0
OR5B21 3632.0
RGS9 3576.0
PDE6G 3464.0
SAG 3438.0
PLS1 3367.0
OR2T8 3364.0
OR4C12 3196.0
GRM1 3106.0
SCNN1G 3050.0
PRKCA 3022.0
OR2L13 3015.0
OR2W3 2986.0
GNAL 2802.0
CALHM3 2772.0
CNGA1 2721.0
OR2K2 2713.0
GPC5 2593.0
MYO3B 2553.0
SCN9A 2552.0
OR6S1 2421.0
OR2D2 2401.0
FNTA 2385.0
NMT2 2340.0
SCN2B 2292.0
TAS2R8 2241.0
PCDH15 2232.0
OR7D4 2168.0
MYO1C 2134.0
SCN2A 2010.0
AKR1C3 2000.0
OR9G4 1998.0
OR51F1 1991.0
RLBP1 1970.0
OR1L4 1953.0
OR5D13 1876.0
GUCA1B 1867.0
CABP1 1792.0
STRC 1510.0
OR5F1 1460.0
OR9I1 1449.0
TAS2R41 1409.0
OR5D18 1406.0
LRP8 1398.0
OR52K1 1312.0
ADCY3 1298.0
OR4C3 1285.0
RDX 1272.0
OR5AN1 1264.0
OR6C3 1228.0
TWF2 1227.0
RDH8 1168.0
OR5D16 1001.0
OR8K1 987.0
OR9Q2 904.0
OR8K5 846.0
OR13C9 839.0
OR4A16 747.0
OR1S2 715.0
LRP2 713.0
OR1J4 504.0
RBP4 448.0
GNAT1 435.0
SCNN1B 405.0
OR1Q1 354.0
RIPOR2 302.0
OR6B3 235.0
OR51B6 189.0
LHX2 124.0
SCN1B 89.0
OR3A2 44.0
OR6F1 17.0
SNAP25 -90.0
OR8B12 -157.0
OR2C3 -199.0
CHRNA10 -255.0
OR10P1 -313.0
OR10A5 -331.0
TMC1 -352.0
ACTB -471.0
OR5M1 -479.0
PJVK -492.0
PCLO -509.0
OR51I2 -535.0
TAS2R50 -779.0
OR13G1 -810.0
OR52W1 -871.0
OPN1SW -944.0
EPB41L3 -1195.0
OR1N2 -1370.0
CAPZA1 -1452.0
OR10Q1 -1522.0
CAPZB -1568.0
OR8U1 -1678.0
OR52D1 -1699.0
OR5L2 -1723.0
GUCY2D -1753.0
LRP10 -1771.0
OR8D2 -1804.0
OR52J3 -1931.0
OR2AE1 -1937.0
RGS9BP -1945.0
OR9G1 -1974.5
OR9G9 -1974.5
OR5M9 -2044.0
TAS2R20 -2049.0
CYP4V2 -2103.0
SPTAN1 -2199.0
OR4X1 -2260.0
OR1B1 -2391.0
GRK4 -2408.0
OR8U8 -2418.0
APOB -2485.0
SDC3 -2624.0
DHRS3 -2631.0
CAPZA2 -2683.0
OR2A12 -2725.0
OR10Z1 -2946.0
SPTBN1 -3118.0
OR1S1 -3152.0
VAMP2 -3158.0
OR14I1 -3220.0
OR5AR1 -3249.0
OR52H1 -3457.0
GNB1 -3520.0
CAMKMT -3697.0
SLC26A5 -3762.0
OR4M1 -3793.0
TWF1 -3867.0
OR4A15 -3896.0
OR2B6 -4052.0
TPRN -4055.0
OTOGL -4069.0
OR2M2 -4079.0
PNLIP -4092.0
METAP2 -4225.0
EZR -4390.0
OR7D2 -4391.0
RDH10 -4671.0
OR8B8 -4699.0
OR51B4 -4790.0
OR4C6 -4796.0
TRIOBP -4858.0
FSCN2 -4875.0
OR2B2 -4943.0
BCO1 -4983.0
OR5J2 -5007.0
TAS2R14 -5013.0
ACTG1 -5045.0
NMT1 -5117.0
RDH11 -5162.0
OR51T1 -5221.0
TAS2R46 -5252.0
APOA1 -5268.0
OR5AP2 -5270.0
OR6C68 -5275.0
LPL -5303.0
USH1G -5309.0
OR5P3 -5362.0
LRAT -5398.0
OR10A3 -5509.0
OR2A14 -5636.0
OR5H6 -5638.0
OR5B17 -5718.0
OR52B2 -5730.0
OR2M7 -5829.0
RBP1 -5871.0
BCO2 -5930.0
OR5T3 -5946.0
NAPEPLD -5995.0
LDLR -6061.0
CLIC5 -6163.0
KCNN2 -6196.0
OR7C2 -6228.0
TAS2R30 -6401.0
OTOP1 -6413.0
METAP1 -6487.0
PRKCQ -6522.0
GNGT1 -6589.0
OR5I1 -6590.0
OR6B1 -6593.0
OR1N1 -6792.0
OR1J1 -6802.0
OR2T1 -6907.0
STX1A -7045.0
OR5K4 -7121.0
OR4E2 -7209.0
WHRN -7331.0
OR2L8 -7359.0
TAS2R4 -7459.0
OR52K2 -7485.0
OR1E2 -7488.0
OR11H4 -7510.0
OR5M3 -7524.0
GSN -7530.0
OR4K13 -7541.0
SCNN1A -7553.0
OR4K5 -7555.0
OR2L2 -7561.0
OR5M8 -7567.0
OR52A1 -7794.0
LRP12 -7926.0
OR6C75 -8072.0
OR7G1 -8140.0
PLCB2 -8365.0
GUCA1C -8396.0
CALM1 -8399.0
LDB1 -8418.0
FNTB -8461.0
DNAJC5 -8494.0
OR4C46 -8540.0
OR4C15 -8636.0
OR5B12 -8772.0
RDH5 -8782.0
TAS2R13 -8824.0
OR5C1 -8985.0
OR51I1 -8998.0
OR5D14 -9007.0
RAB3A -9107.0
OR2AG2 -9213.0
TAS2R43 -9306.0
OR7G3 -9390.0
HSD17B1 -9715.0
OR4X2 -9720.0
PDE6A -9814.0
OR8K3 -9898.0
OR52E2 -9934.0
OR2T4 -9969.0
GNB5 -10046.0
OR1J2 -10047.0
OR6T1 -10143.0
TAS2R1 -10204.0
OR4F6 -10215.0
OR1L8 -10438.0
OR6P1 -10446.0
DHRS9 -10476.0
OR4D5 -10718.0
OR5H1 -10749.0
OR1K1 -10818.0
OR8U3 -10830.0
OR52E6 -10846.0
OR8H3 -10936.0



REACTOME_OLFACTORY_SIGNALING_PATHWAY

REACTOME_OLFACTORY_SIGNALING_PATHWAY
628
set REACTOME_OLFACTORY_SIGNALING_PATHWAY
setSize 348
pANOVA 1.02e-29
s.dist 0.353
p.adjustANOVA 8.34e-27



Top enriched genes

Top 20 genes
GeneID Gene Rank
OR2T3 10981
OR56B4 10966
OR51G2 10949
OR2S2 10925
OR51D1 10910
OR10S1 10907
OR9K2 10881
OR5AU1 10843
OR4D6 10839
OR8B4 10825
OR1A2 10813
OR5T1 10799
OR4D11 10774
OR10J5 10749
OR56A5 10683
OR3A3 10681
OR56A1 10677
OR10C1 10674
OR8A1 10654
OR10J3 10644

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OR2T3 10981.0
OR56B4 10966.0
OR51G2 10949.0
OR2S2 10925.0
OR51D1 10910.0
OR10S1 10907.0
OR9K2 10881.0
OR5AU1 10843.0
OR4D6 10839.0
OR8B4 10825.0
OR1A2 10813.0
OR5T1 10799.0
OR4D11 10774.0
OR10J5 10749.0
OR56A5 10683.0
OR3A3 10681.0
OR56A1 10677.0
OR10C1 10674.0
OR8A1 10654.0
OR10J3 10644.0
OR6K3 10631.0
OR56A3 10616.0
OR4A47 10606.0
OR10H2 10579.0
OR8G5 10563.0
OR10T2 10560.0
OR12D2 10505.0
RTP2 10487.0
OR5A1 10403.0
OR52R1 10369.0
OR8G1 10367.0
OR10J1 10345.0
OR4C16 10301.0
OR9A4 10276.0
OR52I2 10270.0
OR10H3 10263.0
OR6Y1 10233.0
OR14C36 10210.0
OR11L1 10194.0
CNGB1 10176.0
OR3A1 10158.0
OR2C1 10133.0
OR5B2 10128.0
OR10X1 10112.0
OR13F1 10096.0
OR10G4 10094.0
CNGA4 10088.0
OR10K1 10078.0
OR6C6 10073.0
OR1A1 10072.0
OR51S1 10045.0
OR11H6 10042.0
OR5V1 10033.0
OR2M3 10016.0
OR1G1 9976.0
OR2L5 9940.0
OR13D1 9923.0
OR2T6 9915.0
OR9Q1 9826.0
OR2AT4 9812.0
OR6X1 9809.0
OR4D10 9793.0
OR10K2 9777.0
OR51G1 9753.0
OR10V1 9740.0
OR10G9 9691.0
OR6C65 9681.0
RTP1 9662.0
OR4D9 9656.0
OR13C2 9649.0
OR4S1 9582.0
OR52E4 9576.0
OR2W1 9568.0
OR6C1 9548.0
OR6B2 9526.0
OR51A7 9524.0
OR2AP1 9508.0
OR2H2 9481.0
OR4K2 9458.0
OR10W1 9451.0
OR2M4 9446.0
OR11A1 9441.0
OR6C76 9415.0
OR52N2 9409.0
OR8S1 9378.0
OR5K2 9376.0
OR5A2 9374.0
OR6C74 9369.0
OR10AD1 9338.0
OR5K3 9318.0
OR1I1 9296.0
OR4D2 9281.0
OR51B2 9269.0
OR10A4 9265.5
OR2T27 9192.0
OR2A5 9145.0
OR2B11 9116.0
OR5H15 9086.0
OR1F1 9011.0
OR4K17 8992.0
OR5H2 8946.0
OR10A2 8944.0
OR1M1 8930.0
OR6C4 8916.0
OR52M1 8914.0
OR2AG1 8873.0
OR4B1 8781.0
OR7G2 8748.0
OR8J3 8745.0
OR2V2 8741.0
OR4C45 8722.0
OR14J1 8685.0
OR2Y1 8678.0
OR56A4 8672.0
OR1E1 8661.0
OR8B2 8646.0
OR2AK2 8619.0
OR2F2 8599.0
OR52A5 8496.0
OR7A5 8490.0
OR4L1 8478.0
OR4N2 8459.0
OR5T2 8405.0
OR4D1 8387.0
OR5AS1 8365.0
OR4K1 8321.0
OR13J1 8281.0
OR2D3 8267.0
OR1L3 8206.0
OR2T11 8168.0
OR12D3 8153.0
OR10G3 8147.0
OR2A2 8144.0
OR2L3 8139.0
OR5AC2 8130.0
OR5AK2 8100.0
OR14A16 8048.0
OR7E24 8047.0
ANO2 8038.0
GNG13 8027.0
OR10A6 7959.0
OR52N1 7950.0
OR51A2 7949.0
OR51E1 7910.0
OR2V1 7859.0
OR2B3 7834.0
OR52B6 7814.0
OR6C2 7772.0
OR2M5 7628.0
OR2G2 7615.0
OR5M11 7609.0
OR2T12 7535.0
OR2Z1 7509.0
OR2T33 7507.0
OR7C1 7426.0
OR13C8 7419.0
OR4F15 7396.0
OR10AG1 7379.0
OR10H4 7309.0
OR1L1 7279.0
OR9A2 7196.0
OR10H1 7180.0
OR2F1 7075.0
OR5P2 6955.0
OR6A2 6915.0
OR4N5 6854.0
OR6C70 6830.0
OR4K14 6829.0
OR10A7 6815.0
OR10G8 6703.0
OR1D2 6680.0
OR6M1 6664.0
REEP1 6628.0
OR6N1 6546.0
OR5K1 6534.0
OR13C3 6442.0
OR11G2 6390.0
OR10G2 6357.0
OR51B5 6316.0
OR5M10 6177.0
OR13C4 6121.0
OR6Q1 6085.0
OR52E8 6062.0
OR51Q1 6034.0
OR8H1 6024.0
OR6N2 5870.0
OR2G3 5834.0
OR51F2 5721.0
OR13A1 5679.0
OR5L1 5576.0
OR52I1 5534.0
OR51E2 5438.0
OR10G7 5366.0
OR7A17 5356.0
OR2G6 5304.0
OR7A10 5229.0
OR1C1 5211.0
OR6K2 5046.0
OR8D1 4983.0
OR5B3 4814.0
OR56B1 4726.0
OR4A5 4584.0
OR6V1 4523.0
OR51M1 4446.0
OR51V1 4426.0
OR51L1 4414.0
OR5W2 4291.0
OR8D4 4282.0
OR6K6 4257.0
EBF1 4215.0
OR4K15 4102.0
OR8J1 4041.0
OR52L1 3824.0
OR2H1 3821.0
OR8I2 3769.0
OR2J2 3748.0
OR1L6 3743.0
OR10H5 3729.0
OR5B21 3632.0
OR2T8 3364.0
OR4C12 3196.0
OR2L13 3015.0
OR2W3 2986.0
GNAL 2802.0
OR2K2 2713.0
OR6S1 2421.0
OR2D2 2401.0
OR7D4 2168.0
OR9G4 1998.0
OR51F1 1991.0
OR1L4 1953.0
OR5D13 1876.0
OR5F1 1460.0
OR9I1 1449.0
OR5D18 1406.0
OR52K1 1312.0
ADCY3 1298.0
OR4C3 1285.0
OR5AN1 1264.0
OR6C3 1228.0
OR5D16 1001.0
OR8K1 987.0
OR9Q2 904.0
OR8K5 846.0
OR13C9 839.0
OR4A16 747.0
OR1S2 715.0
OR1J4 504.0
OR1Q1 354.0
OR6B3 235.0
OR51B6 189.0
LHX2 124.0
OR3A2 44.0
OR6F1 17.0
OR8B12 -157.0
OR2C3 -199.0
OR10P1 -313.0
OR10A5 -331.0
OR5M1 -479.0
OR51I2 -535.0
OR13G1 -810.0
OR52W1 -871.0
OR1N2 -1370.0
OR10Q1 -1522.0
OR8U1 -1678.0
OR52D1 -1699.0
OR5L2 -1723.0
OR8D2 -1804.0
OR52J3 -1931.0
OR2AE1 -1937.0
OR9G1 -1974.5
OR9G9 -1974.5
OR5M9 -2044.0
OR4X1 -2260.0
OR1B1 -2391.0
OR8U8 -2418.0
OR2A12 -2725.0
OR10Z1 -2946.0
OR1S1 -3152.0
OR14I1 -3220.0
OR5AR1 -3249.0
OR52H1 -3457.0
GNB1 -3520.0
OR4M1 -3793.0
OR4A15 -3896.0
OR2B6 -4052.0
OR2M2 -4079.0
OR7D2 -4391.0
OR8B8 -4699.0
OR51B4 -4790.0
OR4C6 -4796.0
OR2B2 -4943.0
OR5J2 -5007.0
OR51T1 -5221.0
OR5AP2 -5270.0
OR6C68 -5275.0
OR5P3 -5362.0
OR10A3 -5509.0
OR2A14 -5636.0
OR5H6 -5638.0
OR5B17 -5718.0
OR52B2 -5730.0
OR2M7 -5829.0
OR5T3 -5946.0
OR7C2 -6228.0
OR5I1 -6590.0
OR6B1 -6593.0
OR1N1 -6792.0
OR1J1 -6802.0
OR2T1 -6907.0
OR5K4 -7121.0
OR4E2 -7209.0
OR2L8 -7359.0
OR52K2 -7485.0
OR1E2 -7488.0
OR11H4 -7510.0
OR5M3 -7524.0
OR4K13 -7541.0
OR4K5 -7555.0
OR2L2 -7561.0
OR5M8 -7567.0
OR52A1 -7794.0
OR6C75 -8072.0
OR7G1 -8140.0
LDB1 -8418.0
OR4C46 -8540.0
OR4C15 -8636.0
OR5B12 -8772.0
OR5C1 -8985.0
OR51I1 -8998.0
OR5D14 -9007.0
OR2AG2 -9213.0
OR7G3 -9390.0
OR4X2 -9720.0
OR8K3 -9898.0
OR52E2 -9934.0
OR2T4 -9969.0
OR1J2 -10047.0
OR6T1 -10143.0
OR4F6 -10215.0
OR1L8 -10438.0
OR6P1 -10446.0
OR4D5 -10718.0
OR5H1 -10749.0
OR1K1 -10818.0
OR8U3 -10830.0
OR52E6 -10846.0
OR8H3 -10936.0



REACTOME_KERATINIZATION

REACTOME_KERATINIZATION
1073
set REACTOME_KERATINIZATION
setSize 210
pANOVA 2.2e-21
s.dist 0.38
p.adjustANOVA 1.2e-18



Top enriched genes

Top 20 genes
GeneID Gene Rank
KRTAP3-3 10980
KRT15 10965
KRTAP9-9 10865
KRTAP9-1 10805
KRTAP19-1 10787
KRTAP10-7 10783
KRTAP5-6 10779
KRT80 10720
KRT78 10693
KRT33B 10688
KRTAP1-3 10679
KRT74 10568
KRTAP4-4 10544
KRTAP13-3 10499
KRT14 10453
KRT83 10424
KRT40 10422
SPRR2E 10416
KRTAP10-9 10409
KRT6A 10336

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
KRTAP3-3 10980
KRT15 10965
KRTAP9-9 10865
KRTAP9-1 10805
KRTAP19-1 10787
KRTAP10-7 10783
KRTAP5-6 10779
KRT80 10720
KRT78 10693
KRT33B 10688
KRTAP1-3 10679
KRT74 10568
KRTAP4-4 10544
KRTAP13-3 10499
KRT14 10453
KRT83 10424
KRT40 10422
SPRR2E 10416
KRTAP10-9 10409
KRT6A 10336
ST14 10265
SPRR2G 10205
KRT4 10136
KRTAP8-1 10121
KRT82 10074
KRT86 10070
KRT33A 10062
PKP1 10060
LELP1 10025
KRT13 9974
KRTAP25-1 9972
KRT32 9945
KRT5 9891
KRT20 9876
KRTAP4-7 9822
LCE1A 9808
KRT75 9773
KRTAP20-1 9749
KRTAP9-3 9746
LCE5A 9722
LCE1C 9698
KRTAP5-10 9685
LCE4A 9670
KRTAP5-7 9638
KRTAP20-2 9625
KRTAP21-2 9614
LIPK 9600
KRTAP3-1 9599
KRT16 9583
PI3 9507
SPRR3 9438
KRTAP10-4 9417
KRT28 9384
LCE3E 9337
KRT77 9332
KRT37 9315
KRT31 9284
KRT23 9223
KRTAP2-3 9204
TGM1 9199
KRTAP9-4 9118
FLG 9093
KRTAP9-2 9021
KRTAP17-1 9004
KRTAP5-11 8988
SPINK5 8986
KRT85 8924
KRT9 8893
KRT79 8880
PCSK6 8804
LCE2A 8780
SPRR2D 8774
KRT81 8763
KRT76 8737
TGM5 8726
KRT73 8681
JUP 8673
KRTAP4-3 8659
CASP14 8620
KRTAP11-1 8603
DSG4 8578
DSC1 8552
KRTAP13-4 8493
KRTAP1-5 8359
LCE2D 8344
KRT27 8323
KRTAP21-1 8309
KRT35 8308
LCE2C 8237
KRT6C 8140
KRTAP22-1 8123
KRTAP4-6 8031
KRTAP10-12 7998
KRTAP12-4 7992
KAZN 7987
KRT6B 7984
SPRR1A 7964
KRTAP10-10 7879
DSG2 7758
LCE3D 7687
IVL 7649
KRT8 7521
KRT7 7432
KRTAP2-4 7370
KRTAP5-9 7311
KRTAP12-1 7283
SPRR2A 7276
LCE6A 7193
PKP3 7086
KRT72 7076
CDSN 6958
KRTAP23-1 6708
KRTAP10-3 6530
PPL 6231
KRTAP19-2 6197
KRTAP27-1 6119
SPRR1B 6038
KRTAP16-1 5725
LCE1E 5698
KRTAP4-1 5493
KRT12 5176
KRTAP19-8 4965
KRTAP2-2 4672
KRT71 4670
DSP 4643
KRT84 4501
LCE3A 4457
KRT24 4367
PRSS8 4336
KRTAP24-1 4275
KLK12 4208
KRT34 3710
KRTAP1-1 3595
LCE2B 3516
PERP 3332
TCHH 3188
LCE1B 2943
KRTAP4-5 2929
KRTAP4-2 2819
KRT2 2807
KRT10 2690
KRTAP6-1 2107
KRT1 2065
KRT3 1543
KRTAP12-3 1334
KRT26 1231
PKP4 1155
KLK14 1006
KLK13 999
LCE3B 967
KLK8 509
KRTAP13-1 361
KRT19 326
KRT18 312
KRTAP4-8 170
EVPL -391
KRTAP5-3 -527
KRTAP5-8 -557
KRTAP26-1 -930
DSG1 -1295
KRTAP1-4 -1413
KRTAP2-1 -1495
DSG3 -1824
KRTAP13-2 -1942
KRTAP10-1 -1949
FURIN -1963
LCE1F -2002
KRTAP5-2 -2039
KRTAP19-7 -2071
SPINK9 -2100
LIPJ -2347
DSC2 -2375
KRTAP21-3 -2622
KRTAP6-2 -3029
PKP2 -3053
KRTAP10-5 -3069
KRTAP10-6 -3455
KRTAP19-3 -3456
KRTAP19-6 -3788
SPRR2F -3997
KRT39 -4468
RPTN -4589
KRT25 -4626
KRTAP10-2 -5060
CELA2A -5618
CAPNS1 -6102
CAPN1 -6158
KRTAP6-3 -6666
LIPM -6699
KRTAP5-5 -6941
KLK5 -7211
KRTAP10-8 -8344
KRTAP12-2 -8803
KRTAP3-2 -8825
KRTAP19-5 -8909
KRTAP19-4 -8922
KRT38 -9128
KRT36 -9167
DSC3 -9299
KRTAP29-1 -9317
KRTAP5-4 -9548
KRTAP15-1 -9645
KRTAP9-6 -9724
KRTAP5-1 -10426
SPINK6 -10671
LIPN -10699
CSTA -10732
KRTAP10-11 -10836
KRT17 -10884
KRTAP4-11 -10988



REACTOME_NEUTROPHIL_DEGRANULATION

REACTOME_NEUTROPHIL_DEGRANULATION
1053
set REACTOME_NEUTROPHIL_DEGRANULATION
setSize 460
pANOVA 4.79e-21
s.dist -0.256
p.adjustANOVA 1.96e-18



Top enriched genes

Top 20 genes
GeneID Gene Rank
FOLR3 -11001
AZU1 -11000
MPO -10991
FCGR3B -10986
TYROBP -10977
S100A8 -10967
HP -10960
MS4A3 -10959
FCER1G -10931
LRG1 -10874
ELANE -10873
PRTN3 -10865
S100P -10845
VAT1 -10828
RNASE2 -10824
P2RX1 -10816
FGR -10813
STING1 -10809
RNASE3 -10798
CTSG -10796

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FOLR3 -11001
AZU1 -11000
MPO -10991
FCGR3B -10986
TYROBP -10977
S100A8 -10967
HP -10960
MS4A3 -10959
FCER1G -10931
LRG1 -10874
ELANE -10873
PRTN3 -10865
S100P -10845
VAT1 -10828
RNASE2 -10824
P2RX1 -10816
FGR -10813
STING1 -10809
RNASE3 -10798
CTSG -10796
OSCAR -10785
CDA -10763
TARM1 -10741
CEACAM3 -10740
BIN2 -10733
ADGRG3 -10728
CTSD -10727
DEFA4 -10705
BRI3 -10690
SIGLEC9 -10673
RETN -10664
RHOG -10627
PSMB7 -10578
CD63 -10554
C3AR1 -10553
COMMD3 -10537
ATP6V0A1 -10535
OLR1 -10525
PLAC8 -10491
CYB5R3 -10489
SLPI -10488
CTSZ -10474
PLAU -10466
SIRPB1 -10398
S100A9 -10359
HSPA1B -10332
CEACAM6 -10315
PRKCD -10313
PYCARD -10282
BST2 -10269
CLEC12A -10222
CD59 -10212
ADGRE3 -10199
FCAR -10188
UNC13D -10148
S100A11 -10117
PRG3 -10090
TUBB4B -10078
STOM -10067
TNFAIP6 -10036
CEACAM8 -10013
PLD1 -9920
ARMC8 -9901
ADGRE5 -9881
SELL -9837
PLEKHO2 -9793
LAIR1 -9770
OSTF1 -9768
LYZ -9758
SLC15A4 -9739
GHDC -9717
IQGAP2 -9572
ARG1 -9527
RAC1 -9520
RAB3D -9518
STBD1 -9490
DYNLL1 -9489
SLCO4C1 -9467
CREG1 -9464
DYNC1LI1 -9445
MGST1 -9423
CTSA -9402
DBNL -9369
ENPP4 -9368
DNAJC3 -9320
TICAM2 -9315
GMFG -9293
SERPINB1 -9266
NCKAP1L -9254
MCEMP1 -9192
AMPD3 -9178
HSPA8 -9110
RAB3A -9107
TMEM30A -9103
GSTP1 -9087
FPR2 -9070
SVIP -9060
PRDX6 -8994
RAB18 -8986
B4GALT1 -8905
CD177 -8883
VAMP8 -8876
DOK3 -8784
CANT1 -8765
CMTM6 -8713
RAB14 -8674
TSPAN14 -8661
MAPK1 -8617
TMBIM1 -8583
DNAJC5 -8494
CLEC5A -8483
FTH1 -8414
VCL -8392
FLG2 -8382
ADAM8 -8366
ATP6V0C -8341
KCMF1 -8335
PKM -8326
PRG2 -8296
LCN2 -8186
GLIPR1 -8109
APRT -8105
IRAG2 -8070
GM2A -8050
NRAS -7996
CD58 -7963
MNDA -7950
SLC2A3 -7911
CD68 -7905
ACP3 -7830
GUSB -7796
CFD -7790
PLAUR -7776
HSP90AB1 -7735
CXCL1 -7715
PNP -7666
CAND1 -7637
ILF2 -7594
HPSE -7551
NHLRC3 -7545
CTSS -7536
GSN -7530
SURF4 -7475
IMPDH1 -7445
C5AR1 -7405
HSPA1A -7384
TMEM179B -7378
PSAP -7355
HLA-A -7308
VNN1 -7295
GCA -7259
AGPAT2 -7199
CR1 -7165
PTPRJ -7131
ATP8B4 -7120
CPNE3 -7119
LILRB2 -7077
PGM2 -7033
TMEM63A -7019
PRCP -6998
CTSB -6962
GGH -6932
ADAM10 -6926
SNAP23 -6823
DPP7 -6768
FTL -6608
TIMP2 -6599
LPCAT1 -6521
RAB27A -6480
NIT2 -6456
PSMD13 -6393
RAB37 -6372
FUCA1 -6344
FCGR2A -6280
TRPM2 -6213
CAPN1 -6158
RAB31 -6084
QPCT -6054
RAB10 -5924
CPPED1 -5809
ALDOA -5782
ATAD3B -5719
PADI2 -5691
ACTR2 -5655
CKAP4 -5628
SERPINB10 -5601
ATG7 -5557
TNFRSF1B -5497
HGSNAT -5473
RAP1B -5468
RHOA -5450
ROCK1 -5392
PTX3 -5365
CDK13 -5194
RAB7A -5134
ARSB -5118
CAB39 -5099
VAPA -5047
SERPINB6 -4895
HSPA6 -4892
IDH1 -4830
PTPRC -4703
MAN2B1 -4700
VCP -4679
LAMTOR2 -4633
NCSTN -4519
LILRA3 -4516
MAPK14 -4437
CPNE1 -4432
STK10 -4389
YPEL5 -4385
ACLY -4355
LAMTOR3 -4343
DYNC1H1 -4301
HEBP2 -4298
DNAJC13 -4296
CYSTM1 -4291
CLEC4C -4182
PSMD7 -4057
DEGS1 -4044
SDCBP -3961
SCAMP1 -3932
GPI -3859
ERP44 -3774
SLC11A1 -3723
DIAPH1 -3654
PGM1 -3615
CRACR2A -3491
MLEC -3475
RHOF -3411
IGF2R -3375
LTF -3357
ORMDL3 -3349
PPIA -3347
COPB1 -3302
ATP6V1D -3291
ASAH1 -3281
PGLYRP1 -3246
STK11IP -3207
DSN1 -3120
AP1M1 -3083
ANO6 -3062
CLEC4D -3027
ALAD -2979
DERA -2963
CAT -2898
SIGLEC5 -2895
RAB5B -2791
C6orf120 -2782
RAB24 -2776
APAF1 -2771
GNS -2689
CST3 -2614
FABP5 -2493
CD14 -2462
PGAM1 -2336
ARPC5 -2287
HSP90AA1 -2213
A1BG -2204
SPTAN1 -2199
LAMTOR1 -2197
CSNK2B -2185
AGL -2161
PTAFR -2007
HEXB -2003
PSMD14 -1965
NME2 -1778
ALDH3B1 -1747
ITGAL -1703
TXNDC5 -1573
ORM1 -1431
SRP14 -1415
ATP8A1 -1404
HVCN1 -1383
GPR84 -1328
DSG1 -1295
GSDMD -1236
GDI2 -1214
ANXA2 -1205
DYNLT1 -1121
CCT2 -979
RAB6A -961
TUBB -950
ALOX5 -896
PSMC2 -840
UBR4 -782
PSMD6 -684
TCIRG1 -659
ITGAM -621
XRCC5 -615
TOLLIP -613
PSMD11 -524
CAP1 -499
PSMB1 -483
HMGB1 -457
PFKL -403
HRNR -302
NFKB1 -285
PDXK -259
PECAM1 -258
SLC2A5 -235
SNAP25 -90
RAB4B 70
HMOX2 98
CEP290 127
IQGAP1 143
CYBA 145
RAP1A 316
XRCC6 352
PSMD12 373
HLA-C 426
ATP11B 431
FUCA2 472
KPNB1 488
CD47 496
RAB5C 623
PAFAH1B2 687
ITGAV 688
MVP 690
IST1 734
PSMA2 776
LGALS3 781
NPC2 934
ARSA 989
DOCK2 995
HK3 1022
PSMD3 1087
ADA2 1098
CEACAM1 1152
CRISPLD2 1165
GRN 1219
MMP9 1241
QSOX1 1274
NEU1 1282
GOLGA7 1326
KCNAB2 1328
TRAPPC1 1479
GYG1 1486
GALNS 1741
PSMA5 1847
TOM1 1972
AP2A2 1989
MMP25 2001
KRT1 2065
PYGL 2073
MANBA 2080
CTSC 2104
PPIE 2138
RNASET2 2184
PTPRB 2226
ARL8A 2270
PTPN6 2285
AGA 2299
EEF2 2310
PSEN1 2391
S100A12 2532
NDUFC2 2637
TCN1 2641
SLC44A2 2692
ACAA1 2975
PTPRN2 3031
EEF1A1 3054
PSMD1 3155
APEH 3165
CD33 3238
B2M 3334
C1orf35 3357
EPX 3443
RAP2B 3449
CNN2 3453
TBC1D10C 3455
ITGAX 3467
ABCA13 3603
PPBP 3636
PRSS3 3689
LTA4H 3700
CXCR2 3747
PDAP1 3751
C3 3779
ATP11A 3806
CCT8 3952
DGAT1 3992
CD44 4031
FCN1 4162
CTSH 4226
NFAM1 4271
ACTR1B 4339
TLR2 4622
DSP 4643
ITGB2 4649
CD300A 4727
CD55 4766
NBEAL2 4785
CRISP3 4791
COMMD9 4852
HLA-B 5059
SIGLEC14 5164
AOC1 5360
FAF2 5547
VPS35L 5552
PSMC3 5724
GLB1 5752
FRK 5873
CHIT1 5895
RAB44 5981
SYNGR1 6014
ARHGAP9 6082
LRRC7 6207
FGL2 6305
CD36 6422
ACTR10 6469
MGAM 6542
BST1 6562
SERPINA3 6571
IMPDH2 6606
BPI 6662
SIRPA 6749
SERPINA1 6864
CAMP 6935
ARHGAP45 6940
COTL1 7010
TMC6 7073
MIF 7208
CD53 7437
NAPRT 7508
GAA 7596
LAMP1 7641
CYFIP1 7726
DDOST 7801
PA2G4 7837
SNAP29 7925
CHRNB4 7941
NFASC 7989
LILRB3 8127
ANPEP 8250
PSMD2 8298
OLFM4 8324
CHI3L1 8418
HBB 8442
CXCR1 8450
ORM2 8524
MMP8 8545
DSC1 8552
CD93 8597
FPR1 8655
JUP 8673
SLC27A2 8790
PYGB 8921
MME 9262
AHSG 9334
SERPINB3 9529
S100A7 9601
ALDOC 9669
PIGR 9711
TTR 9756
PTGES2 9800
CSTB 9838
PKP1 10060
SERPINB12 10122
CALML5 10619



REACTOME_CELLULAR_RESPONSES_TO_STIMULI

REACTOME_CELLULAR_RESPONSES_TO_STIMULI
1314
set REACTOME_CELLULAR_RESPONSES_TO_STIMULI
setSize 779
pANOVA 6.41e-18
s.dist -0.182
p.adjustANOVA 2.1e-15



Top enriched genes

Top 20 genes
GeneID Gene Rank
MIR24-2 -10899
TLR4 -10819
RPS6KA1 -10777
H2BC6 -10708
RLN1 -10675
XBP1 -10652
H3C6 -10650
DDX11 -10599
PSMB7 -10578
CALR -10512
ETS2 -10506
SOD2 -10496
NLRP3 -10484
POM121C -10473
LIMD1 -10431
FKBP5 -10424
TUBA3D -10346
HSPA1B -10332
PRKCD -10313
DCTN2 -10239

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MIR24-2 -10899.0
TLR4 -10819.0
RPS6KA1 -10777.0
H2BC6 -10708.0
RLN1 -10675.0
XBP1 -10652.0
H3C6 -10650.0
DDX11 -10599.0
PSMB7 -10578.0
CALR -10512.0
ETS2 -10506.0
SOD2 -10496.0
NLRP3 -10484.0
POM121C -10473.0
LIMD1 -10431.0
FKBP5 -10424.0
TUBA3D -10346.0
HSPA1B -10332.0
PRKCD -10313.0
DCTN2 -10239.0
CXCL8 -10206.0
GPX1 -10165.0
IL6 -10121.0
ACADVL -10084.0
CSRP1 -10080.0
TUBB4B -10078.0
H1-0 -10051.0
SHC1 -10031.0
MAFG -9997.0
AGO4 -9949.0
H4C3 -9942.0
TALDO1 -9936.0
NFE2L2 -9875.0
CSNK2A1 -9812.0
EP300 -9776.0
TPP1 -9756.0
CREB3 -9711.0
RPL29 -9703.0
CHD9 -9689.0
CCNE2 -9681.0
ATP6V1E2 -9669.0
H2BC12 -9581.0
UBC -9558.0
PSMD5 -9539.0
MAPKAPK3 -9529.0
NBN -9502.0
H4C11 -9492.0
DYNLL1 -9489.0
H4C9 -9486.0
DYNC1LI1 -9445.0
ATP6V0E2 -9413.0
RPLP1 -9411.0
GPX8 -9381.0
H2BC5 -9371.0
NRIP1 -9352.0
ATP6V1A -9350.0
DNAJC3 -9320.0
BMI1 -9287.0
H3-3A -9260.0
CREB3L4 -9233.0
RPS23 -9195.0
H4C16 -9179.0
MIR24-1 -9163.0
CBX6 -9157.0
TXN -9118.0
HSPA8 -9110.0
H2AC4 -9092.0
ATP6V0B -9091.0
GSTP1 -9087.0
BLVRB -9084.0
UBE2E1 -9071.0
RAE1 -9026.0
PRDX6 -8994.0
E2F2 -8947.0
CXXC1 -8916.0
TINF2 -8864.0
CSNK2A2 -8850.0
TKT -8827.0
TUBB4A -8809.0
CBX8 -8780.0
MTF1 -8779.0
RB1 -8767.0
SESN2 -8751.0
RPS29 -8722.0
NPLOC4 -8719.0
FNIP2 -8712.0
HM13 -8705.0
MT1M -8695.0
H1-3 -8667.0
MAPK1 -8617.0
CDC16 -8598.0
MAP3K5 -8582.0
MED1 -8570.0
MLST8 -8569.0
TFDP2 -8530.0
ATP6V1B2 -8528.0
FKBP14 -8521.0
COX20 -8517.0
H2BC1 -8504.0
PPP2R5B -8503.0
TXNIP -8480.0
NCOR2 -8471.0
MAP2K6 -8430.0
H4C13 -8401.0
HMGA2 -8387.0
H3-3B -8363.0
ATP6V0C -8341.0
ABCC1 -8329.0
ATP6V0E1 -8311.0
PHC3 -8272.0
H3C8 -8260.0
H2BC3 -8237.0
EXOSC5 -8187.0
TFDP1 -8155.0
H2BC8 -8108.0
PSME1 -8101.0
CDK6 -8085.0
RPL11 -8055.0
CDK2 -8046.0
HIF1A -8044.0
EGLN3 -8022.0
WIPI1 -8001.0
PSMA6 -7988.0
EXOSC7 -7984.0
NCOA2 -7957.0
DEPDC5 -7906.0
NUP50 -7820.0
RBX1 -7781.0
PHC1 -7771.0
CDKN2A -7757.0
MAPKAPK2 -7751.0
HSP90AB1 -7735.0
CDKN2B -7709.0
GFPT1 -7687.0
H3C11 -7686.0
AGO3 -7679.0
EZH2 -7675.0
MIOS -7650.0
NUP93 -7632.0
RAI1 -7620.0
CRTC3 -7583.0
CDKN2C -7581.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
TNRC6B -7491.0
RPL22 -7474.0
MUL1 -7466.0
NCF2 -7461.0
CREB3L2 -7460.0
FZR1 -7430.0
HSPA1A -7384.0
CASTOR1 -7369.0
H2AJ -7338.0
MEF2C -7222.0
BACH1 -7220.0
CUL3 -7084.0
UBN1 -7049.0
MINK1 -7041.0
EED -7009.0
ME1 -7006.0
FAU -6993.0
ADD1 -6978.0
H2BC10 -6977.0
H3C3 -6933.0
ATP6V1E1 -6928.0
HYOU1 -6918.0
CUL1 -6904.0
MAP1LC3B -6900.0
RPL27 -6893.0
ARNT -6865.0
TUBAL3 -6859.0
CEBPB -6830.0
TUBA4A -6826.0
H3C12 -6825.0
PRDX3 -6824.0
RPL23 -6779.0
DNAJC2 -6767.0
CDKN1B -6757.0
COX19 -6756.0
RPL21 -6753.0
TRIB3 -6745.0
H2AC8 -6733.0
ERN1 -6723.0
CTDSP2 -6712.0
EDEM1 -6706.0
DNAJC7 -6703.0
HBA2 -6670.0
DPP3 -6656.0
RXRA -6640.0
COX7A2L -6623.0
PGD -6602.0
GSR -6596.0
RPS9 -6580.0
GPX7 -6575.0
SCO1 -6569.0
COX6A1 -6563.0
RPL34 -6560.0
IMPACT -6554.0
DYNC1I2 -6523.0
H2AC18 -6516.5
H2AC19 -6516.5
TUBB3 -6481.0
NFYB -6475.0
KICS2 -6431.0
SLC46A1 -6414.0
TUBA4B -6407.0
PSMD13 -6393.0
COX4I1 -6386.0
RPL10A -6330.0
SCO2 -6325.0
ID1 -6322.0
MT1A -6306.0
MAPKAPK5 -6287.0
PSMC6 -6219.0
GSTA3 -6183.0
DNAJB6 -6159.0
SEC13 -6136.0
CA9 -6133.0
PSME2 -6132.0
H2BC14 -6126.0
COX7C -6123.0
CDC26 -6099.0
ANAPC10 -6095.0
ACTR1A -6083.0
TUBA1A -6069.0
AGO1 -6050.0
EGLN1 -6015.0
SP1 -5960.0
TACO1 -5949.0
NUP155 -5935.0
RNF2 -5882.0
GPX2 -5878.0
ANAPC7 -5877.0
HSPA2 -5868.0
PTGES3 -5864.0
SERP1 -5842.0
PPP1R15A -5784.0
YIF1A -5772.0
BMT2 -5751.0
FNIP1 -5692.0
MRE11 -5675.0
HSPA4L -5645.0
ATM -5608.0
HSPB1 -5590.0
GSK3B -5572.0
ATP6V1G1 -5563.0
MAFK -5528.0
CAMK2D -5489.0
RPS20 -5483.0
VENTX -5482.0
H3C2 -5478.0
MBTPS1 -5476.0
SEC31A -5444.0
UBXN7 -5421.0
TUBB2A -5397.0
CBX2 -5379.0
H2AC7 -5340.5
H2BC7 -5340.5
NUP153 -5310.0
EXOSC4 -5302.0
POM121 -5300.0
SOD3 -5299.0
APOA1 -5268.0
DCTN6 -5234.0
CDK4 -5202.0
NR3C2 -5189.0
KAT5 -5079.0
VEGFA -5078.0
CDKN1A -5005.0
ETS1 -4955.0
RPS26 -4941.0
ATR -4921.0
DDIT3 -4896.0
HSPA6 -4892.0
ERO1A -4880.0
IDH1 -4830.0
BAG4 -4817.0
GPX3 -4768.0
AKT1S1 -4755.0
ELOC -4748.0
RPL9 -4728.0
VCP -4679.0
MYDGF -4656.0
POT1 -4645.0
LAMTOR2 -4633.0
PSMB10 -4606.0
STAT3 -4580.0
RPL18 -4575.0
TUBB6 -4561.0
GSTA1 -4558.0
EIF2S1 -4551.0
XPO1 -4530.0
MOV10 -4504.0
EPO -4479.0
NDUFA4 -4469.0
E2F3 -4451.0
TNRC6C -4438.0
MAPK14 -4437.0
COX14 -4397.0
AKT1 -4393.0
PSMB2 -4344.0
LAMTOR3 -4343.0
TXNRD1 -4302.0
DYNC1H1 -4301.0
EIF2AK4 -4294.0
KDELR3 -4232.0
HIKESHI -4229.0
MAPK9 -4226.0
EIF2AK1 -4202.0
FBXL17 -4179.0
CDC23 -4153.0
NUP188 -4141.0
MAP2K7 -4122.0
PSMD7 -4057.0
CDC27 -4025.0
SURF1 -4018.0
TBL1XR1 -4015.0
H4C4 -4007.0
NUP133 -3990.0
HSPA14 -3959.0
RPL15 -3918.0
MT1G -3882.0
GSK3A -3880.0
TNIK -3843.0
HMGA1 -3826.0
BLVRA -3823.0
TGS1 -3798.0
PRDX5 -3772.0
NFYA -3765.0
H2BC21 -3732.0
UBE2D2 -3692.0
RELA -3661.0
MAPK7 -3657.0
NCOA1 -3650.0
RPL26 -3628.0
AKT3 -3595.0
GPX5 -3577.0
RPL10L -3574.0
H4C6 -3568.0
RPS27 -3484.0
PSMA7 -3416.0
CYCS -3407.0
NR3C1 -3398.0
H2AC14 -3377.0
RPL30 -3326.0
ATP6V1D -3291.0
H1-2 -3287.0
SESN1 -3275.0
KDM6B -3253.0
PSME3 -3245.0
SKP1 -3229.0
ATP6V1F -3217.0
DCTN4 -3208.0
PALB2 -3191.0
TUBA1C -3186.0
NUP42 -3160.0
PARN -3133.0
HSF1 -3114.0
EHMT2 -3061.0
H3C4 -3045.0
CAT -2898.0
MAP2K4 -2820.0
PSMC4 -2787.0
SQSTM1 -2777.0
NPRL2 -2745.0
CCNA1 -2724.0
NUP98 -2703.0
CAPZA2 -2683.0
NCF4 -2678.0
NPRL3 -2667.0
ERF -2621.0
STIP1 -2550.0
RPL4 -2541.0
KHSRP -2535.0
TUBA8 -2524.0
ATP6V1C1 -2518.0
COX16 -2510.0
NUP160 -2508.0
APOB -2485.0
SSR1 -2477.0
EP400 -2470.0
HBA1 -2430.0
CAMK2G -2428.0
RPS6 -2406.0
ATP6V1H -2333.0
MRPL18 -2324.0
LY96 -2317.0
H1-4 -2279.0
PRDX2 -2230.0
HSP90AA1 -2213.0
LAMTOR1 -2197.0
HDGF -2190.0
CSNK2B -2185.0
SEM1 -2183.0
DYNC1I1 -2149.0
TUBB2B -2109.0
ANAPC5 -2079.0
BAG2 -2074.0
MYC -2072.0
NUP35 -2059.0
BAG5 -2043.0
DCTN1 -2023.0
PSMB6 -1996.0
PSMD14 -1965.0
PREB -1919.0
COX6C -1852.0
GCLM -1832.0
MAP2K3 -1752.0
LRPPRC -1749.0
ITFG2 -1722.0
RPL24 -1718.0
CUL2 -1702.0
RRAGA -1665.0
DNAJA1 -1636.0
TERF1 -1604.0
CLOCK -1601.0
EIF2AK3 -1584.0
CAPZB -1568.0
HSPA1L -1557.0
H1-5 -1539.0
RPS25 -1469.0
LMNB1 -1456.0
PSMD9 -1453.0
CAPZA1 -1452.0
HSP90B1 -1447.0
PHC2 -1440.0
RPL5 -1417.0
SIN3A -1392.0
RPL18A -1362.0
RPS19 -1355.0
PSMC5 -1352.0
RPL13 -1344.0
EXTL3 -1336.0
HSPA5 -1335.0
LAMTOR4 -1274.0
IGFBP7 -1265.0
HIF1AN -1246.0
PDIA6 -1227.0
TXNRD2 -1218.0
GOSR2 -1204.0
PSMB4 -1200.0
TXN2 -1176.0
H3C10 -1128.0
CCNE1 -1118.0
MT1E -1113.0
EHMT1 -1095.0
H4C12 -1092.0
MDM2 -1085.0
DEDD2 -1068.0
NOX4 -1035.0
PSMA3 -989.0
COX6B1 -915.0
AAAS -910.0
DNAJA2 -900.0
MT1F -898.0
RING1 -863.0
H4C2 -859.0
PSMC2 -840.0
TP53 -831.0
NUP37 -825.0
RPL27A -824.0
CLEC1B -792.0
SKP2 -722.0
NCOA6 -707.0
UBE2C -706.0
SLC38A9 -700.0
RPS15A -688.0
PSMD6 -684.0
RRAGD -670.0
TCIRG1 -659.0
RPL37A -652.0
UFD1 -637.0
RPS19BP1 -633.0
ATOX1 -617.0
RPS27L -610.0
CREB3L3 -578.0
NUP43 -528.0
PSMD11 -524.0
ANAPC15 -493.0
NUP214 -489.0
PSMB1 -483.0
COX18 -423.0
PSMA4 -398.0
TUBA3C -374.0
TNFRSF21 -354.0
BAG1 -346.0
EXOSC1 -322.0
RPL35 -307.0
RPL28 -294.0
NFKB1 -285.0
MT2A -191.0
RPS8 -175.0
EXOSC3 -159.0
TLN1 -133.0
TUBA3E -95.0
MDM4 -86.0
RPL35A -84.0
SYVN1 -66.0
RBBP4 -33.0
SCMH1 -17.0
H2BC13 1.0
UBE2S 7.0
PRDX1 13.0
PSMD4 55.0
MEF2D 68.0
TERF2IP 79.0
COX11 91.0
HMOX2 98.0
ATF6 115.0
P4HB 134.0
CYBA 145.0
DNAJB9 168.0
GML 178.0
RPS16 186.0
PPARA 293.0
DNAJB1 300.0
NFYC 314.0
NUP85 327.0
WDR59 364.0
PSMD12 373.0
ACD 384.5
RPL26L1 397.0
CREBRF 402.0
BRCA1 456.0
RPSA 473.0
DIS3 523.0
EPAS1 547.0
PSMF1 550.0
GCLC 576.0
TATDN2 579.0
FOS 612.0
ATP6V1G2 619.0
EXOSC2 621.0
RPL6 651.0
CCAR2 655.0
USP46 691.0
RPL12 711.0
DCP2 726.0
ASNS 737.0
VHL 752.0
PSMA2 776.0
SZT2 817.0
H3-4 835.0
ANAPC11 853.0
ATF2 857.0
ELOB 914.0
HIF3A 948.0
NUP54 1027.0
ST13 1061.0
YWHAE 1068.0
DNAJB11 1077.0
PSMD3 1087.0
PSMB9 1093.0
RPS15 1149.0
ANAPC4 1161.0
RANBP2 1258.0
H1-1 1304.0
UBB 1320.0
RPL41 1365.0
EXOSC8 1377.0
H4C8 1444.0
NQO1 1491.0
UBE2D3 1527.0
RPA2 1570.0
H2BC26 1619.0
HSPA4 1623.0
EXTL1 1665.0
HIGD1A 1725.0
KLHDC3 1740.0
NUP88 1774.0
NCOR1 1776.0
ATF3 1782.0
RPS10 1837.0
PSMA5 1847.0
TNRC6A 1957.0
LAMTOR5 1974.0
PSMB8 2004.0
MT3 2029.0
RPLP2 2085.0
NUP210 2136.0
RPL19 2149.0
BTRC 2163.0
PSMA1 2177.0
EGLN2 2182.0
ANAPC16 2196.0
H2BC15 2203.0
CREB1 2212.0
RPS27A 2313.0
NUP107 2333.0
H2BC4 2363.0
LMNA 2364.0
ASF1A 2389.0
BAG3 2412.0
COX5B 2447.0
NDC1 2461.0
HDAC3 2573.0
H4C1 2583.0
DYNC1LI2 2640.0
UBA52 2643.0
CUL7 2681.0
FLCN 2709.0
SIRT1 2715.0
IFNB1 2718.0
RORA 2729.0
PSMD8 2754.0
RPL14 2784.0
CBX4 2785.0
MAPK10 2866.0
KEAP1 2884.0
MT1X 2965.0
GCN1 2977.0
CRYBA4 2999.0
JUN 3045.0
EEF1A1 3054.0
PSME4 3100.0
NR1D1 3146.0
PSMD1 3155.0
ATP6V1B1 3158.0
BMAL1 3170.0
H2AC20 3179.0
RPL38 3205.0
RPL32 3206.0
PGR 3276.0
MAP4K4 3287.0
CABIN1 3355.0
NUDT2 3356.0
RPTOR 3371.0
AJUBA 3376.0
NOTCH1 3378.0
RPS12 3386.0
ATF4 3388.0
HSPA13 3414.0
FKBP4 3431.0
GRB10 3468.0
MAPK8 3520.0
CITED2 3538.0
TERF2 3655.0
SIN3B 3728.0
RPS21 3781.0
HIRA 3863.0
ALB 4005.0
EXOSC9 4007.0
RPL39L 4074.0
RPS24 4090.0
RPL23A 4115.0
H2BC17 4130.0
RPS6KA2 4142.0
COX5A 4199.0
KPTN 4287.0
RHEB 4307.0
ANAPC1 4318.0
HSPH1 4401.0
EXTL2 4445.0
HSPB8 4448.0
NUP58 4456.0
RPS14 4497.0
SRPRA 4543.0
ANAPC2 4548.0
H2BC11 4657.0
TUBA1B 4671.0
STAP2 4682.0
H3C1 4735.0
RPA3 4736.0
PSMC1 4758.0
CRTC1 4821.0
DNAJA4 4840.0
RPL17 4856.0
ZBTB17 4860.0
RPL7 4972.0
RPS3A 4982.0
PSMB3 5015.0
PPARGC1A 5113.0
SNCB 5161.0
WFS1 5166.0
HMOX1 5202.0
RPL37 5203.0
CCNA2 5235.0
SMARCD3 5277.0
RPL8 5290.0
CREB3L1 5387.0
ATP6V0D2 5393.0
H4C5 5401.0
CEBPG 5409.0
ATP6V0D1 5442.0
EIF2S2 5445.0
H2AZ2 5485.0
RPL22L1 5560.0
TUBB1 5561.0
SRPRB 5657.0
MT1H 5662.0
PSMC3 5724.0
CREBBP 5734.0
RPS18 5744.0
DCTN5 5779.0
PSMB5 5798.0
AKT2 5824.0
SUZ12 5843.0
SOD1 5891.0
RPL36AL 5907.5
SERPINH1 5918.0
SRXN1 5955.0
RPS13 6012.0
RPL31 6025.0
MTOR 6030.0
COX8A 6060.0
RPS5 6091.0
RPS28 6113.0
CCS 6173.0
PDIA5 6176.0
RPL3 6271.0
SLC7A11 6391.0
H2AC6 6426.0
HSPA9 6457.0
ACTR10 6469.0
NOX5 6493.0
RRAGC 6521.0
CRTC2 6556.0
CAMK2B 6604.0
RAD50 6618.0
RPS7 6631.0
CCL2 6647.0
ATP6V1C2 6655.0
HELZ2 6711.0
H2AX 6737.0
RPLP0 6807.0
CHAC1 6868.0
NUP205 6912.0
WTIP 6941.0
RPL7A 7052.0
UBE2D1 7063.0
RPA1 7064.0
E2F1 7131.0
TPR 7154.0
RPS2 7273.0
IGFBP1 7302.0
PTK6 7450.0
CAPZA3 7525.0
NUP62 7697.0
CARM1 7764.0
DCTN3 7804.0
GPX6 7883.0
ATP6V1G3 7885.0
MAPK3 7947.0
RPS11 7972.0
HERPUD1 8189.0
WDR24 8246.0
EXOSC6 8249.0
FABP1 8263.0
PSMD2 8298.0
DCSTAMP 8312.0
PLA2G4B 8427.0
SH3BP4 8439.0
SEH1L 8440.0
HSBP1 8441.0
HBB 8442.0
RPL36 8538.0
CDKN2D 8586.0
RPS3 8628.0
NPAS2 8715.0
ARFGAP1 8891.0
PSMA8 8939.0
MAPK11 8999.0
DYNLL2 9125.0
HSPA12A 9183.0
HSPA12B 9205.0
TRIM21 9666.0
AQP8 9729.0
ATF5 9895.0
CRYAB 9924.0
RPL3L 10001.0
RPL13A 10152.5
IL1A 10212.0
PSMB11 10222.0
HSPB2 10245.0
MT4 10268.0
CAMK2A 10502.0
TUBB8 10871.0
MT1B 10892.0



REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE
1082
set REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE
setSize 125
pANOVA 1.02e-17
s.dist 0.444
p.adjustANOVA 2.79e-15



Top enriched genes

Top 20 genes
GeneID Gene Rank
KRT15 10965
KRT80 10720
KRT78 10693
KRT33B 10688
KRT74 10568
KRT14 10453
KRT83 10424
KRT40 10422
SPRR2E 10416
KRT6A 10336
ST14 10265
SPRR2G 10205
KRT4 10136
KRT82 10074
KRT86 10070
KRT33A 10062
PKP1 10060
LELP1 10025
KRT13 9974
KRT32 9945

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
KRT15 10965
KRT80 10720
KRT78 10693
KRT33B 10688
KRT74 10568
KRT14 10453
KRT83 10424
KRT40 10422
SPRR2E 10416
KRT6A 10336
ST14 10265
SPRR2G 10205
KRT4 10136
KRT82 10074
KRT86 10070
KRT33A 10062
PKP1 10060
LELP1 10025
KRT13 9974
KRT32 9945
KRT5 9891
KRT20 9876
LCE1A 9808
KRT75 9773
LCE5A 9722
LCE1C 9698
LCE4A 9670
LIPK 9600
KRT16 9583
PI3 9507
SPRR3 9438
KRT28 9384
LCE3E 9337
KRT77 9332
KRT37 9315
KRT31 9284
KRT23 9223
TGM1 9199
FLG 9093
SPINK5 8986
KRT85 8924
KRT9 8893
KRT79 8880
PCSK6 8804
LCE2A 8780
SPRR2D 8774
KRT81 8763
KRT76 8737
TGM5 8726
KRT73 8681
JUP 8673
CASP14 8620
DSG4 8578
DSC1 8552
LCE2D 8344
KRT27 8323
KRT35 8308
LCE2C 8237
KRT6C 8140
KAZN 7987
KRT6B 7984
SPRR1A 7964
DSG2 7758
LCE3D 7687
IVL 7649
KRT8 7521
KRT7 7432
SPRR2A 7276
LCE6A 7193
PKP3 7086
KRT72 7076
CDSN 6958
PPL 6231
SPRR1B 6038
LCE1E 5698
KRT12 5176
KRT71 4670
DSP 4643
KRT84 4501
LCE3A 4457
KRT24 4367
PRSS8 4336
KLK12 4208
KRT34 3710
LCE2B 3516
PERP 3332
TCHH 3188
LCE1B 2943
KRT2 2807
KRT10 2690
KRT1 2065
KRT3 1543
KRT26 1231
PKP4 1155
KLK14 1006
KLK13 999
LCE3B 967
KLK8 509
KRT19 326
KRT18 312
EVPL -391
DSG1 -1295
DSG3 -1824
FURIN -1963
LCE1F -2002
SPINK9 -2100
LIPJ -2347
DSC2 -2375
PKP2 -3053
SPRR2F -3997
KRT39 -4468
RPTN -4589
KRT25 -4626
CELA2A -5618
CAPNS1 -6102
CAPN1 -6158
LIPM -6699
KLK5 -7211
KRT38 -9128
KRT36 -9167
DSC3 -9299
SPINK6 -10671
LIPN -10699
CSTA -10732
KRT17 -10884



REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
1161
set REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
setSize 1336
pANOVA 7.46e-16
s.dist -0.131
p.adjustANOVA 1.75e-13



Top enriched genes

Top 20 genes
GeneID Gene Rank
NFE2 -10939
MIR24-2 -10899
MIR27A -10861
ZNF124 -10833
ZNF717 -10801
SPI1 -10725
H2BC6 -10708
RETN -10664
H3C6 -10650
ZNF710 -10632
ZNF597 -10604
PSMB7 -10578
NLRC4 -10566
ZNF738 -10564
PIP4K2C -10542
SOD2 -10496
GATA2 -10464
IL3 -10437
FKBP5 -10424
ZNF680 -10413

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NFE2 -10939.0
MIR24-2 -10899.0
MIR27A -10861.0
ZNF124 -10833.0
ZNF717 -10801.0
SPI1 -10725.0
H2BC6 -10708.0
RETN -10664.0
H3C6 -10650.0
ZNF710 -10632.0
ZNF597 -10604.0
PSMB7 -10578.0
NLRC4 -10566.0
ZNF738 -10564.0
PIP4K2C -10542.0
SOD2 -10496.0
GATA2 -10464.0
IL3 -10437.0
FKBP5 -10424.0
ZNF680 -10413.0
POLR2C -10372.0
ZIM2 -10329.0
ZNF770 -10314.0
ZNF175 -10309.0
ZNF75A -10308.0
RMI2 -10267.0
MYB -10255.0
DDX39B -10247.0
ERCC3 -10242.0
GP1BA -10230.0
KAT6A -10229.0
CASP10 -10209.0
YWHAG -10207.0
PCGF6 -10193.0
SESN3 -10179.0
ZNF732 -10134.0
IL6 -10121.0
ZNF519 -10099.0
SOCS3 -10048.0
FOXG1 -10044.0
RARG -9989.0
ZNF692 -9975.0
RARA -9950.0
AGO4 -9949.0
H4C3 -9942.0
MAML1 -9886.0
ZNF700 -9854.0
LMO2 -9851.0
LBR -9832.0
CSNK2A1 -9812.0
YAF2 -9795.0
EP300 -9776.0
EAF2 -9736.0
U2AF1L4 -9688.0
CCNE2 -9681.0
NFATC2 -9680.0
NR1H3 -9671.0
THOC1 -9668.0
HTT -9643.0
CCNG2 -9605.0
H2BC12 -9581.0
ZNF587 -9566.0
BLM -9563.0
UBC -9558.0
PSMD5 -9539.0
TAL1 -9534.0
NBN -9502.0
RNU11 -9493.0
H4C11 -9492.0
H4C9 -9486.0
CNOT10 -9481.0
CCNG1 -9440.0
ITGA5 -9438.0
ZNF418 -9430.0
TP53BP2 -9416.0
RUNX1 -9414.0
RBBP5 -9393.0
RYBP -9384.0
H2BC5 -9371.0
ZNF429 -9355.0
ZNF562 -9354.0
CITED4 -9322.0
HES1 -9292.0
BMI1 -9287.0
H3-3A -9260.0
CDC25C -9256.0
SMARCC2 -9250.0
ZNF785 -9246.0
MSX2 -9239.0
ZNF223 -9227.0
YES1 -9222.0
PCGF5 -9194.0
H4C16 -9179.0
MIR24-1 -9163.0
CBX6 -9157.0
ZNF426 -9152.0
CHEK1 -9151.0
RAD51D -9148.0
SNAPC3 -9130.0
ZNF521 -9125.0
TXN -9118.0
ARID3A -9109.0
H2AC4 -9092.0
UBE2E1 -9071.0
GATA3 -9064.0
KMT5A -9054.0
ZNF282 -9002.0
GADD45A -9000.0
CSF2 -8999.0
ZNF25 -8991.0
SGK1 -8979.0
ZNF577 -8970.0
ZNF300 -8967.0
GAD1 -8935.0
HAND2 -8898.0
DDB2 -8878.0
GAMT -8875.0
HUS1 -8871.0
SYMPK -8870.0
CASP1 -8859.0
CSNK2A2 -8850.0
ZNF492 -8848.0
TP53RK -8826.0
KRAS -8798.0
ZNF649 -8790.0
CBX8 -8780.0
RB1 -8767.0
CASP6 -8753.0
SESN2 -8751.0
GATAD2B -8745.0
CASP2 -8729.0
ZC3H11A -8724.0
ZNF202 -8720.0
NR4A2 -8717.0
ZNF273 -8704.0
RUNX2 -8699.0
ZNF560 -8625.0
MAPK1 -8617.0
CDC16 -8598.0
EAF1 -8596.0
ZNF764 -8578.0
MED1 -8570.0
MLST8 -8569.0
PABPN1 -8563.0
CBX5 -8555.0
TFDP2 -8530.0
COX20 -8517.0
TGFA -8513.0
H2BC1 -8504.0
ZNF74 -8481.0
TXNIP -8480.0
KAT2B -8472.0
NCOR2 -8471.0
IGFBP3 -8436.0
MAP2K6 -8430.0
LDB1 -8418.0
SPP1 -8408.0
H4C13 -8401.0
CALM1 -8399.0
H3-3B -8363.0
PIP4P1 -8351.0
AXIN1 -8331.0
ZNF772 -8312.0
ZNF28 -8285.0
GTF2A2 -8284.0
PHC3 -8272.0
H3C8 -8260.0
ZNF383 -8243.0
CCN2 -8241.0
H2BC3 -8237.0
ZNF431 -8230.0
ZNF70 -8223.0
CNOT8 -8208.0
SMARCA2 -8188.0
RBL1 -8170.0
TFDP1 -8155.0
H2BC8 -8108.0
PSME1 -8101.0
ZNF561 -8100.0
CDK6 -8085.0
TWIST1 -8084.0
RAD1 -8063.0
ZNF420 -8057.0
NDRG1 -8051.0
CDK2 -8046.0
TAF12 -8042.0
PHF20 -8020.0
PSMA6 -7988.0
SUPT4H1 -7958.0
SNRPB -7928.0
CGA -7924.0
SLC2A3 -7911.0
ZNF658 -7908.0
ESRRA -7889.0
ZNF747 -7864.0
PCNA -7849.0
CNOT6L -7826.0
RRM2B -7813.0
PMS2 -7786.0
RBX1 -7781.0
PHC1 -7771.0
SREBF1 -7759.0
CDKN2A -7757.0
ZNF619 -7730.0
ZNF517 -7723.0
CDKN2B -7709.0
CLDN5 -7705.0
BBC3 -7702.0
POLR2K -7697.0
H3C11 -7686.0
PRMT1 -7681.0
AGO3 -7679.0
EZH2 -7675.0
ZNF214 -7660.0
ZNF543 -7640.0
TNFRSF18 -7578.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
TNRC6B -7491.0
SNAPC5 -7486.0
ZNF433 -7479.0
ZNF266 -7462.0
CPSF3 -7434.0
FZR1 -7430.0
KIT -7421.0
NR2C2 -7414.0
H2AJ -7338.0
ATRIP -7316.0
CPSF2 -7300.0
POLR2A -7267.0
CDK9 -7238.0
MEF2C -7222.0
THRA -7212.0
ZNF439 -7194.0
TCF12 -7186.0
ZNF746 -7180.0
CR1 -7165.0
ZFP37 -7141.0
ZNF195 -7122.0
PBRM1 -7061.0
EED -7009.0
NR4A3 -6991.0
ZKSCAN4 -6984.0
H2BC10 -6977.0
FOXO3 -6952.0
INTS13 -6947.0
H3C3 -6933.0
MAF -6929.0
CUL1 -6904.0
ZNF77 -6890.0
DGCR8 -6884.0
CBFB -6875.0
ARNT -6865.0
ZNF33A -6850.0
ASH2L -6843.0
CEBPB -6830.0
H3C12 -6825.0
RPAP2 -6815.0
POU4F1 -6814.0
TEAD3 -6804.0
PML -6800.0
MIR132 -6775.0
CDKN1B -6757.0
COX19 -6756.0
H2AC8 -6733.0
ZNF3 -6683.0
ZNF564 -6679.0
TP53I3 -6677.0
RXRA -6640.0
LSM11 -6638.0
MED25 -6634.0
COX7A2L -6623.0
GTF2B -6622.0
MED17 -6603.0
GSR -6596.0
SCO1 -6569.0
COX6A1 -6563.0
TAF15 -6543.0
GTF2F1 -6537.0
PRKCQ -6522.0
H2AC18 -6516.5
H2AC19 -6516.5
NFYB -6475.0
PRKAA1 -6472.0
INTS9 -6454.0
ZNF425 -6452.0
INTS7 -6451.0
HIPK1 -6449.0
TFAP2A -6427.0
ZNF620 -6426.0
ARID2 -6420.0
TGIF2 -6409.0
PSMD13 -6393.0
PPARG -6392.0
COX4I1 -6386.0
GRIA2 -6385.0
MAX -6379.0
ALYREF -6332.0
SCO2 -6325.0
YWHAH -6318.0
AIFM2 -6303.0
CCND2 -6290.0
MAPKAPK5 -6287.0
PSMC6 -6219.0
ZNF641 -6214.0
SMAD7 -6202.0
HDAC10 -6199.0
PIP4K2A -6189.0
YWHAZ -6164.0
NABP1 -6143.0
PSME2 -6132.0
TP53INP1 -6127.0
H2BC14 -6126.0
COX7C -6123.0
CCNH -6119.0
ZNF528 -6111.0
ZNF286A -6108.0
HEY2 -6104.0
CDC26 -6099.0
ANAPC10 -6095.0
NKX2-5 -6075.0
CPSF6 -6065.0
AGO1 -6050.0
HDAC9 -6043.0
MGA -6039.0
NABP2 -6035.0
INTS4 -6025.0
CCND3 -5993.0
CRADD -5985.0
SP1 -5960.0
TACO1 -5949.0
KMT2D -5933.0
INTS1 -5931.0
ZNF333 -5917.0
MBD3 -5903.0
RNF2 -5882.0
GPX2 -5878.0
ANAPC7 -5877.0
POU2F1 -5859.0
AURKA -5849.0
ZNF804B -5834.0
POU4F2 -5822.0
E2F5 -5820.0
PRR5 -5818.0
BARD1 -5779.0
STUB1 -5764.0
PRELID1 -5708.0
PTEN -5677.0
MRE11 -5675.0
ZNF436 -5672.0
E2F8 -5629.0
ATM -5608.0
RBBP8 -5574.0
GSK3B -5572.0
HDAC2 -5534.0
ZNF621 -5529.0
ZNF565 -5500.0
FYTTD1 -5498.0
CAMK2D -5489.0
TIGAR -5488.0
VENTX -5482.0
H3C2 -5478.0
ZNF211 -5477.0
RNGTT -5471.0
ZNF782 -5431.0
TMEM219 -5410.0
GTF2E1 -5387.0
CBX2 -5379.0
RFFL -5368.0
ZNF135 -5366.0
H2AC7 -5340.5
H2BC7 -5340.5
TRIM28 -5298.0
NPY -5278.0
TNFRSF10B -5251.0
ZNF417 -5219.0
CHEK2 -5211.0
ZNF625 -5207.0
CDK4 -5202.0
CDK13 -5194.0
NR3C2 -5189.0
NKX3-2 -5179.0
TAF4B -5149.0
YY1 -5148.0
FAS -5132.0
ZNF615 -5126.0
BCL6 -5121.0
ZNF398 -5116.0
SSRP1 -5110.0
KDM5B -5100.0
MAML2 -5093.0
PAPOLA -5086.0
KAT5 -5079.0
VEGFA -5078.0
RICTOR -5024.0
L3MBTL1 -5021.0
ZNF180 -5016.0
CDKN1A -5005.0
TRIM33 -5000.0
PLAGL1 -4952.0
ZNF468 -4942.0
SMARCE1 -4940.0
ZNF682 -4939.0
PTPN1 -4938.0
ATR -4921.0
SMARCD1 -4900.0
DDIT3 -4896.0
ZKSCAN3 -4894.0
SNRPD3 -4881.0
THOC6 -4859.0
CTSL -4854.0
ZNF668 -4772.0
MED31 -4763.0
NR2F1 -4758.0
RBPJ -4754.0
ZNF793 -4751.0
ELOC -4748.0
ZNF189 -4744.0
SMURF1 -4720.0
PHAX -4711.0
GPAM -4680.0
MEAF6 -4676.0
VDR -4667.0
SOX2 -4650.0
LAMTOR2 -4633.0
IL2RA -4619.0
PSMB10 -4606.0
TAF8 -4604.0
AFF4 -4590.0
RORB -4554.0
INTS12 -4547.0
ZNF750 -4533.0
XPO1 -4530.0
MLLT3 -4518.0
MOV10 -4504.0
NDUFA4 -4469.0
NELFB -4457.0
TNRC6C -4438.0
MAPK14 -4437.0
COX14 -4397.0
AKT1 -4393.0
PRKAB1 -4382.0
ZNF730 -4381.0
GTF2H5 -4378.0
ELF1 -4376.0
TFAP2C -4370.0
TAF7 -4369.0
PSMB2 -4344.0
LAMTOR3 -4343.0
TRIAP1 -4326.0
ZNF557 -4319.0
TXNRD1 -4302.0
TNFRSF10C -4290.0
ZFP69B -4260.0
BDNF -4251.0
GTF2A1 -4237.0
TBP -4230.0
ZNF551 -4219.0
CASC3 -4204.0
ZNF699 -4196.0
ZFPM1 -4194.0
ZFP2 -4159.0
PLK2 -4154.0
CDC23 -4153.0
ELL -4130.0
ZNF707 -4128.0
ZNF688 -4124.0
INTS3 -4099.0
GAD2 -4095.0
CTDP1 -4083.0
PSMD7 -4057.0
ZNF100 -4056.0
ZNF611 -4033.0
CDC27 -4025.0
SURF1 -4018.0
TBL1XR1 -4015.0
H4C4 -4007.0
ABCA6 -3994.0
TJP1 -3989.0
ICE1 -3982.0
ZNF221 -3964.0
ARID1B -3929.0
ELL3 -3900.0
DPY30 -3892.0
RPRD1A -3889.0
GPI -3859.0
RFC5 -3853.0
IHH -3789.0
PRDX5 -3772.0
NFYA -3765.0
ZFP28 -3747.0
JUNB -3746.0
H2BC21 -3732.0
CPSF7 -3727.0
CDK8 -3720.0
HDAC7 -3704.0
ZNF684 -3664.0
BRD7 -3663.0
RELA -3661.0
NOC2L -3651.0
GTF2H1 -3642.0
ZNF224 -3633.0
SKI -3613.0
ZNF670 -3607.0
ZNF34 -3596.0
AKT3 -3595.0
SLU7 -3585.0
ZNF559 -3580.0
H4C6 -3568.0
ZNF79 -3557.0
ZNF530 -3546.0
CDC73 -3539.0
CNOT7 -3535.0
ZNF268 -3510.0
RNU12 -3454.0
ZNF709 -3450.0
ZNF724 -3432.0
PSMA7 -3416.0
CYCS -3407.0
PIN1 -3401.0
NR3C1 -3398.0
ZNF317 -3395.0
SOX9 -3393.0
RXRB -3388.0
H2AC14 -3377.0
ZNF626 -3367.0
JMY -3352.0
ZNF573 -3338.0
ESR2 -3312.0
SESN1 -3275.0
BRPF3 -3268.0
RAD51 -3266.0
ZNF264 -3264.0
ITGBL1 -3259.0
PSME3 -3245.0
MNAT1 -3244.0
SKP1 -3229.0
ITCH -3210.0
PRKCB -3201.0
TAF2 -3194.0
CNOT1 -3172.0
ZNF215 -3171.0
BRD2 -3153.0
TAF9 -3142.0
PMAIP1 -3107.0
SMYD2 -3103.0
ZNF394 -3077.0
EHMT2 -3061.0
HIVEP3 -3054.0
SMAD2 -3052.0
H3C4 -3045.0
DHX38 -3019.0
ZNF248 -3012.0
MTA2 -2984.0
ZNF254 -2975.0
E2F4 -2971.0
ZNF839 -2965.0
MAPKAP1 -2964.0
ZNF510 -2941.0
RBM8A -2924.0
MAGOHB -2907.0
CAT -2898.0
POLR2I -2893.0
KMT2E -2890.0
ING2 -2880.0
RFC4 -2868.0
AURKB -2861.0
ZNF112 -2853.0
RFC3 -2823.0
ZNF200 -2812.0
PSMC4 -2787.0
APAF1 -2771.0
THOC5 -2762.0
ZNF599 -2757.0
SNW1 -2756.0
HEY1 -2747.0
CDK1 -2730.0
CCNA1 -2724.0
SUPT16H -2715.0
DDX39A -2652.0
CNOT2 -2651.0
GPS2 -2644.0
ZNF589 -2642.0
SNRPF -2638.0
ICE2 -2627.0
POLR2B -2615.0
GTF2H3 -2584.0
NR2E3 -2583.0
MED8 -2545.0
ZNF143 -2532.0
SMARCD2 -2528.0
INTS2 -2513.0
COX16 -2510.0
SKIL -2490.0
ZNF584 -2489.0
PPP2CB -2471.0
NR1D2 -2435.0
CAMK2G -2428.0
MED4 -2423.0
BMP2 -2411.0
GATAD2A -2405.0
ZNF213 -2396.0
ZNF662 -2388.0
CTR9 -2373.0
TGFB1 -2362.0
ZNF154 -2358.0
ZNF549 -2357.0
MAML3 -2354.0
EPC1 -2346.0
TFAP2E -2342.0
BCL2L11 -2331.0
PITX2 -2309.0
PTPN11 -2297.0
ZNF529 -2289.0
ZNF681 -2248.0
PRDX2 -2230.0
LAMTOR1 -2197.0
ELOA2 -2193.0
NR4A1 -2192.0
CSNK2B -2185.0
SEM1 -2183.0
MED20 -2177.0
DYRK2 -2168.0
ZNF324B -2139.0
SETD1A -2122.0
SUMO1 -2089.0
ANAPC5 -2079.0
RAD17 -2076.0
MYC -2072.0
RTF1 -2066.0
TCF7L2 -2035.0
ZNF230 -2016.0
ZNF540 -2009.0
SRF -1998.0
PSMB6 -1996.0
PPM1D -1992.0
MED24 -1973.0
PSMD14 -1965.0
FURIN -1963.0
ESRRG -1953.0
FANCC -1907.0
ITGA4 -1906.0
ZNF320 -1900.0
MSTN -1894.0
BID -1872.0
ZNF470 -1870.0
COX6C -1852.0
NPPA -1813.0
SMAD4 -1810.0
YBX1 -1801.0
LRPPRC -1749.0
ZNF212 -1737.0
ITGAL -1703.0
RRAGA -1665.0
TTC5 -1646.0
ZNF550 -1643.0
ZNF790 -1640.0
SRSF11 -1618.0
DLL1 -1614.0
ZNF729 -1588.0
NRBF2 -1580.0
HIPK2 -1566.0
GRIN2A -1550.0
ZNF304 -1537.0
ZNF226 -1521.0
ZNF17 -1520.0
ZNF585A -1509.0
ZNF613 -1491.0
ZC3H8 -1464.0
PSMD9 -1453.0
PHC2 -1440.0
ZFP30 -1435.0
MED23 -1420.0
TFAP2D -1414.0
EXO1 -1398.0
SIN3A -1392.0
NCBP2 -1379.0
PRKAG1 -1371.0
PSMC5 -1352.0
RPRD2 -1318.0
CNOT4 -1314.0
TBX5 -1309.0
LAMTOR4 -1274.0
ZNF471 -1253.0
POLR2G -1251.0
CNOT6 -1230.0
PRKAA2 -1220.0
ERBB2 -1219.0
PSMB4 -1200.0
FOXO1 -1192.0
ZNF607 -1167.0
ZNF696 -1159.0
BTG1 -1156.0
ZNF706 -1146.0
ZNF568 -1144.0
KMT2A -1135.0
ZNF234 -1131.0
POLDIP3 -1130.0
H3C10 -1128.0
CCNE1 -1118.0
ZSCAN25 -1112.0
RMI1 -1101.0
SNAPC1 -1100.0
ZNF605 -1098.0
EHMT1 -1095.0
H4C12 -1092.0
MDM2 -1085.0
RHNO1 -1080.0
TNKS1BP1 -1066.0
ZNF343 -1063.0
ZNF655 -1047.0
L3MBTL2 -1031.0
DEK -1023.0
RAD9B -1016.0
ZNF547 -1009.0
ZNF669 -1003.0
ZNF382 -991.0
PSMA3 -989.0
ZNF627 -987.0
PINK1 -982.0
RSPO3 -947.0
PRKACA -933.0
NR1I2 -924.0
COX6B1 -915.0
ZNF726 -911.0
ZNF786 -908.0
BAX -888.0
RING1 -863.0
H4C2 -859.0
ZNF274 -852.0
PSMC2 -840.0
CPSF1 -834.0
TP53 -831.0
MED6 -830.0
NR5A2 -826.0
INTS10 -809.0
MED13 -788.0
TAF3 -770.0
NR2E1 -763.0
TGIF1 -761.0
SKP2 -722.0
OPRK1 -719.0
ZNF331 -708.0
UBE2C -706.0
SLC38A9 -700.0
PSMD6 -684.0
USP2 -680.0
RRAGD -670.0
REST -668.0
MAGOH -667.0
RBFOX1 -661.0
MEN1 -632.0
ZKSCAN8 -628.0
ZNF792 -620.0
HDAC11 -618.0
DLX6 -574.0
ABL1 -558.0
ZNF791 -553.0
MED27 -550.0
PSMD11 -524.0
TEAD2 -514.0
RPRD1B -494.0
ANAPC15 -493.0
RAD9A -486.0
ZKSCAN1 -484.0
PSMB1 -483.0
PPARD -473.0
ZNF441 -456.0
COX18 -423.0
PSMA4 -398.0
HNF4G -393.0
ZNF567 -370.0
MLH1 -367.0
ZNF554 -355.0
ZNF493 -342.0
NCBP1 -338.0
ZNF227 -326.0
ZNF571 -304.0
NFKB1 -285.0
SATB2 -271.0
RNU4ATAC -247.0
KRBOX5 -233.0
OCLN -230.0
ARID1A -221.0
ZNF324 -208.0
ZNF205 -207.0
ZIK1 -204.0
ZNF546 -186.0
PCBP4 -174.0
FASLG -129.0
ZNF20 -128.0
SMURF2 -126.0
TSC1 -111.0
ZNF350 -101.0
PRKAG2 -89.0
MDM4 -86.0
ZNF496 -61.0
TNFRSF10A -44.0
RBBP4 -33.0
SCMH1 -17.0
YWHAQ -11.0
PCF11 -6.0
H2BC13 1.0
UBE2S 7.0
PRDX1 13.0
ZNF660 16.0
CDC7 20.0
YEATS4 48.0
PSMD4 55.0
DDIT4 61.0
TCF3 67.0
COX11 91.0
ZNF285 128.0
HDAC4 140.0
INTS14 152.0
WDR5 156.0
NR1H4 161.0
CBX3 174.0
RNF111 210.0
ZNF708 242.0
ACTL6A 268.0
SKIC8 283.0
PPARA 293.0
NFYC 314.0
CHD3 338.0
GTF2E2 347.0
PSMD12 373.0
PPP2R5C 395.0
E2F6 396.0
ZNF133 436.0
ZNF442 437.0
ZFP1 449.0
BRCA1 456.0
SNAPC2 459.0
FIP1L1 462.0
PRMT5 482.0
ZNF689 492.0
SYT10 499.0
RABGGTA 515.0
ACTL6B 524.0
GTF2F2 536.0
PSMF1 550.0
BNIP3L 557.0
ZNF713 565.0
PRELID3A 588.0
EIF4A3 601.0
ZNF606 603.0
FOS 612.0
BANP 616.0
MLLT1 633.0
ZNF721 641.0
GLS 658.0
ZNF678 668.0
ING5 674.0
ZNF443 718.0
ZNF2 731.0
ZNF664 748.0
TAF13 758.0
CLP1 765.0
PSMA2 776.0
LGALS3 781.0
UBE2I 794.0
ZNF263 807.0
CDK12 819.0
SOCS4 829.0
ZNF775 838.0
ANAPC11 853.0
ATF2 857.0
CNOT9 886.0
SMAD3 908.0
ZNF614 909.0
ELOB 914.0
KMT2C 917.0
LEO1 931.0
WWP1 942.0
SRSF6 956.0
PCGF2 970.0
ZNF184 990.0
FBXW7 1013.0
ZNF665 1019.0
WWOX 1026.0
YWHAE 1068.0
SRSF4 1082.0
PSMD3 1087.0
PDPK1 1090.0
PSMB9 1093.0
E2F7 1096.0
CCND1 1122.0
ZNF14 1125.0
ANAPC4 1161.0
SP7 1192.0
DAXX 1201.0
LMO1 1210.0
CAV1 1218.0
MDC1 1223.0
ZNF141 1278.0
ZNF761 1280.0
ZNF771 1293.0
UBB 1320.0
ZNF140 1327.0
INTS8 1383.0
MED10 1384.0
ZNF555 1390.0
RBM14 1408.0
ZNF415 1412.0
H4C8 1444.0
SRSF2 1473.0
SARNP 1480.0
SETD1B 1496.0
UBE2D3 1527.0
ELL2 1529.0
WRN 1553.0
RPA2 1570.0
ZNF461 1575.0
MIR137 1576.0
NR2F6 1592.0
SRSF9 1611.0
H2BC26 1619.0
IWS1 1621.0
ZNF354C 1674.0
CCNT2 1685.0
CHTOP 1723.0
SUPT5H 1775.0
NCOR1 1776.0
ZNF416 1790.0
YWHAB 1797.0
FANCD2 1800.0
ZNF704 1801.0
TAF1L 1828.0
SIRT3 1838.0
PSMA5 1847.0
CDK7 1850.0
ITGA2B 1860.0
ZNF585B 1864.0
PRDM7 1869.0
ZNF267 1871.0
ZNF675 1889.0
POLR2L 1891.0
DLX5 1905.0
TNRC6A 1957.0
LAMTOR5 1974.0
SUPT6H 1996.0
PSMB8 2004.0
HSPD1 2009.0
PPP2R1B 2037.0
SETD9 2053.0
RRM2 2113.0
AGO2 2114.0
JAG1 2142.0
CDC40 2164.0
PRDM1 2166.0
PSMA1 2177.0
ANAPC16 2196.0
H2BC15 2203.0
CREB1 2212.0
TPX2 2214.0
BRD1 2222.0
AUTS2 2227.0
ZNF12 2262.0
ZNF563 2269.0
NPM1 2295.0
ZNF454 2300.0
SMAD1 2302.0
CSTF2T 2312.0
RPS27A 2313.0
ERCC2 2323.0
CTNNB1 2329.0
KCTD6 2338.0
ZNF486 2346.0
H2BC4 2363.0
TFAP2B 2366.0
ZNF703 2390.0
USP7 2400.0
MMP13 2405.0
CENPJ 2408.0
ZNF875 2411.0
ELF2 2413.0
PPM1A 2414.0
STK11 2424.0
ZNF777 2435.0
ZNF714 2436.0
COX5B 2447.0
GPRIN1 2453.0
CNOT11 2470.0
ZNF250 2496.0
WDR33 2504.0
POU2F2 2513.0
CAMK4 2540.0
TP63 2558.0
HDAC3 2573.0
INTS5 2574.0
ZNF45 2578.0
H4C1 2583.0
ZNF778 2603.0
BRIP1 2607.0
PPP2CA 2625.0
UBA52 2643.0
THRB 2680.0
ZNF197 2702.0
SIRT1 2715.0
ATXN3 2716.0
RORA 2729.0
PLK3 2742.0
PSMD8 2754.0
CCNC 2761.0
NELFCD 2763.0
CBX4 2785.0
ZNF235 2797.0
SRSF7 2820.0
DNA2 2831.0
NR0B2 2894.0
NELFE 2912.0
ATAD2 2930.0
RFC2 2936.0
ZNF225 2940.0
NR2C1 3044.0
JUN 3045.0
THOC7 3051.0
ZNF691 3075.0
POLR2H 3091.0
ZNF566 3097.0
PSME4 3100.0
NR1D1 3146.0
PSMD1 3155.0
BMAL1 3170.0
H2AC20 3179.0
CSTF1 3207.0
MET 3208.0
BCL2L14 3255.0
RABGGTB 3261.0
PGR 3276.0
ZNF26 3290.0
PPP1R13L 3311.0
CCNB1 3317.0
PERP 3332.0
ZNF385A 3333.0
ZNF208 3358.0
RPTOR 3371.0
NOTCH1 3378.0
INTS6 3429.0
ZNF610 3451.0
ZNF624 3483.0
ZNF37A 3494.0
TRPC3 3502.0
TAF10 3510.0
CITED2 3538.0
RARB 3559.0
FBXO32 3579.0
ZNF43 3588.0
CCNK 3604.0
ZNF136 3662.0
ZNF114 3676.0
MED7 3693.0
ZNF10 3695.0
NELFA 3698.0
POLR2F 3701.0
CNOT3 3705.0
MSH2 3713.0
RNF34 3727.0
SIN3B 3728.0
ZNF616 3737.0
PPP1R13B 3749.0
NR6A1 3758.0
ZNF473 3788.0
ZNF514 3791.0
ELOA 3804.0
TAF5 3845.0
PIP4K2B 3878.0
KAT2A 3907.0
PRMT6 3920.0
RBL2 3958.0
SSU72 4012.0
ZNF490 4019.0
ZNF160 4063.0
SRSF5 4080.0
ZNF432 4084.0
YAP1 4098.0
ZNF679 4120.0
H2BC17 4130.0
COL1A2 4150.0
ZNF302 4155.0
TEAD1 4192.0
COX5A 4199.0
ZNF735 4236.0
ZFHX3 4250.0
ZNF337 4273.0
RHEB 4307.0
ANAPC1 4318.0
ZNF440 4324.0
IQSEC3 4330.0
ZNF33B 4337.0
SMARCA4 4350.0
PTPN4 4351.0
PAF1 4354.0
BTG2 4411.0
IL2 4413.0
POLR2E 4421.0
ZFP69 4434.0
TP73 4436.0
ZSCAN32 4453.0
ZNF311 4455.0
U2AF2 4467.0
ZNF169 4481.0
SNRPE 4508.0
ZNF30 4512.0
GATA4 4528.0
ANAPC2 4548.0
ZNF776 4570.0
NOP2 4647.0
MED26 4651.0
H2BC11 4657.0
ZNF354B 4664.0
ZNF774 4696.0
ZNF253 4703.0
H3C1 4735.0
RPA3 4736.0
TOPBP1 4738.0
MYBL2 4741.0
SRRM1 4756.0
PSMC1 4758.0
ESR1 4769.0
ZNF799 4799.0
ZNF671 4801.0
OPRM1 4806.0
GRIN2B 4844.0
BGLAP 4869.0
WWTR1 4882.0
ZNF256 4883.0
TSC2 4893.0
NRBP1 4913.0
HDAC1 4949.0
TAF11 4988.0
INTS11 4992.0
CPSF4 4996.0
RET 5013.0
PSMB3 5015.0
NAMPT 5031.0
SERPINB13 5042.0
ZNF483 5048.0
NEDD4L 5051.0
ZNF582 5061.0
PPARGC1B 5110.0
PPARGC1A 5113.0
NR1H2 5134.0
PIDD1 5138.0
SRSF3 5215.0
LIFR 5220.0
NOTCH3 5228.0
CCNA2 5235.0
LEF1 5275.0
SMARCD3 5277.0
CSTF3 5325.0
KCTD1 5334.0
PLXNA4 5349.0
ZNF667 5355.0
ZNF480 5385.0
ZNF446 5388.0
KLF4 5392.0
H4C5 5401.0
NOTCH4 5452.0
ZNF19 5453.0
ZNF347 5455.0
H2AZ2 5485.0
PRKAB2 5499.0
ZNF718 5549.0
ZNF23 5558.0
CSF1R 5570.0
STAT1 5574.0
TAF4 5622.0
ZNF697 5637.0
ZNF354A 5650.0
ZNF500 5666.0
RGCC 5680.0
SRC 5689.0
ZNF287 5695.0
MED15 5703.0
EGFR 5712.0
PSMC3 5724.0
CREBBP 5734.0
ZKSCAN5 5791.0
PSMB5 5798.0
ZNF430 5811.0
GTF2H4 5821.0
AKT2 5824.0
SUZ12 5843.0
THBS1 5846.0
ZNF544 5856.0
APOE 5875.0
TEAD4 5894.0
TOP3A 5902.0
MTOR 6030.0
ZNF484 6037.0
COX8A 6060.0
CTSV 6149.0
RBFOX3 6158.0
SST 6185.0
SLBP 6194.0
PPP2R1A 6221.0
AGRP 6232.0
CHD4 6248.0
ZNF445 6256.0
NUAK1 6275.0
ZFP90 6280.0
ZNF92 6281.0
ZNF18 6296.0
SNRPG 6360.0
MED16 6377.0
GEM 6386.0
ZNF740 6420.0
H2AC6 6426.0
LSM10 6471.0
ZNF138 6504.0
RRAGC 6521.0
NUDT21 6524.0
TCEA1 6529.0
SNAPC4 6577.0
CAMK2B 6604.0
RAD50 6618.0
HDAC5 6649.0
ZIM3 6675.0
ZNF548 6683.0
ZNF479 6686.0
GLS2 6706.0
H2AX 6737.0
ZFP14 6782.0
CTSK 6865.0
POMC 6961.0
PARP1 6975.0
BRPF1 6984.0
ZNF334 7001.0
ESRRB 7013.0
SMARCC1 7024.0
UBE2D1 7063.0
RPA1 7064.0
E2F1 7131.0
CCNT1 7156.0
KCTD15 7167.0
TNFRSF10D 7174.0
CRH 7188.0
NR1I3 7207.0
RNPS1 7215.0
ZNF596 7224.0
NR2C2AP 7228.0
PAX5 7252.0
IGFBP1 7302.0
PVALB 7339.0
BIRC5 7359.0
ZNF552 7365.0
ZNF222 7405.0
SRRT 7538.0
FANCI 7545.0
SMAD6 7550.0
IFNG 7597.0
CGB5 7621.0
SRSF1 7624.0
ZNF485 7712.0
NR5A1 7725.0
TWIST2 7734.0
CARM1 7764.0
G6PC1 7796.0
ZNF101 7826.0
ZNF460 7827.0
GCK 7831.0
ZNF257 7895.0
ZNF773 7911.0
BLK 7915.0
GLI3 7928.0
MAPK3 7947.0
RXRG 7954.0
TAF6 7963.0
ZNF569 8043.0
ZNF155 8052.0
SERPINE1 8055.0
FOXO6 8085.0
POLR2D 8105.0
MOBP 8190.0
ZNF600 8284.0
ZNF586 8294.0
PSMD2 8298.0
ZNF558 8302.0
ZNF701 8327.0
NPAS4 8343.0
RUNX3 8368.0
ZNF677 8390.0
KRBA1 8392.0
ZNF727 8434.0
RNMT 8555.0
PF4 8611.0
MED30 8648.0
ZNF506 8713.0
ZKSCAN7 8796.0
COL1A1 8811.0
TCF7L1 8847.0
ZNF749 8867.0
ZNF716 8917.0
ARNT2 8927.0
PSMA8 8939.0
ZNF71 8968.0
MAPK11 8999.0
ZNF860 9067.0
ZNF99 9172.0
ZNF419 9201.0
ZNF570 9301.0
INS 9345.0
CDK5 9357.0
ZNF583 9387.0
HNF4A 9401.0
ZNF595 9499.0
GLI2 9562.0
PCK1 9703.0
ZNF556 9734.0
TCF7 9744.0
NOTCH2 9769.0
ZNF737 9771.0
PRKAG3 9785.0
MYL9 9962.0
KMT2B 10017.0
CDK5R1 10081.0
TRIM63 10087.0
SMARCB1 10098.0
KCNIP3 10108.0
SFN 10169.0
ZNF736 10196.0
PSMB11 10222.0
POLR2J 10234.0
RORC 10305.0
ZNF676 10350.0
ZNF233 10362.0
THOC3 10456.0
STEAP3 10470.0
CAMK2A 10502.0
CTLA4 10548.0
TP53AIP1 10590.0
UCMA 10786.0
CGB8 10856.0



REACTOME_CELL_CYCLE_MITOTIC

REACTOME_CELL_CYCLE_MITOTIC
1112
set REACTOME_CELL_CYCLE_MITOTIC
setSize 539
pANOVA 1.97e-15
s.dist -0.2
p.adjustANOVA 4.04e-13



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708
H3C6 -10650
CSNK1E -10595
PSMB7 -10578
POM121C -10473
TUBA3D -10346
DCTN2 -10239
YWHAG -10207
TUBB4B -10078
TUBG2 -10039
H4C3 -9942
LBR -9832
CSNK2A1 -9812
EP300 -9776
CCNE2 -9681
SMC2 -9640
CEP41 -9604
H2BC12 -9581
UBC -9558
PSMD5 -9539

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
H3C6 -10650.0
CSNK1E -10595.0
PSMB7 -10578.0
POM121C -10473.0
TUBA3D -10346.0
DCTN2 -10239.0
YWHAG -10207.0
TUBB4B -10078.0
TUBG2 -10039.0
H4C3 -9942.0
LBR -9832.0
CSNK2A1 -9812.0
EP300 -9776.0
CCNE2 -9681.0
SMC2 -9640.0
CEP41 -9604.0
H2BC12 -9581.0
UBC -9558.0
PSMD5 -9539.0
H4C11 -9492.0
DYNLL1 -9489.0
H4C9 -9486.0
DYNC1LI1 -9445.0
H2BC5 -9371.0
NEK9 -9304.0
H3-3A -9260.0
CDC25C -9256.0
H4C16 -9179.0
TK1 -9168.0
RAB2A -9166.0
H2AC4 -9092.0
UBE2E1 -9071.0
KMT5A -9054.0
RAE1 -9026.0
CLIP1 -8978.0
E2F2 -8947.0
RAB8A -8934.0
FBXL18 -8861.0
CSNK2A2 -8850.0
CNEP1R1 -8817.0
TUBB4A -8809.0
CENPA -8800.0
RB1 -8767.0
PDS5A -8763.0
CHMP4A -8725.0
MAPK1 -8617.0
CDC16 -8598.0
NEK7 -8538.0
TFDP2 -8530.0
H2BC1 -8504.0
PPP2R5B -8503.0
HAUS2 -8502.0
NME7 -8404.0
H4C13 -8401.0
H3-3B -8363.0
PCM1 -8345.0
NSL1 -8302.0
CNTRL -8294.0
H3C8 -8260.0
H2BC3 -8237.0
CENPQ -8231.0
RBL1 -8170.0
TFDP1 -8155.0
CDC25A -8146.0
MZT2A -8124.0
H2BC8 -8108.0
PSME1 -8101.0
CDK6 -8085.0
CDK2 -8046.0
PSMA6 -7988.0
NDE1 -7893.0
PRIM1 -7890.0
PCNA -7849.0
NUP50 -7820.0
NEDD1 -7817.0
KIF2C -7797.0
RBX1 -7781.0
ZWINT -7770.0
CCNB2 -7768.0
CDKN2A -7757.0
NUDC -7747.0
HSP90AB1 -7735.0
CDKN2B -7709.0
H3C11 -7686.0
CEP72 -7656.0
NUP93 -7632.0
CDKN2C -7581.0
CEP43 -7565.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
POLE4 -7505.0
FZR1 -7430.0
H2AJ -7338.0
ESCO2 -7333.0
ENSA -7326.0
CHMP2B -7324.0
PTTG1 -7296.0
ZWILCH -7287.0
GORASP1 -7243.0
FKBPL -7151.0
ODF2 -7132.0
CEP78 -7050.0
OPTN -7047.0
CEP70 -7040.0
H2BC10 -6977.0
BUB1B -6938.0
H3C3 -6933.0
CUL1 -6904.0
TUBAL3 -6859.0
FBXL7 -6851.0
TUBA4A -6826.0
H3C12 -6825.0
BLZF1 -6782.0
ORC2 -6761.0
CDKN1B -6757.0
H2AC8 -6733.0
LIN54 -6650.0
VRK2 -6642.0
CDK5RAP2 -6558.0
DYNC1I2 -6523.0
H2AC18 -6516.5
H2AC19 -6516.5
LIN52 -6507.0
TUBB3 -6481.0
TUBA4B -6407.0
PSMD13 -6393.0
CLASP2 -6389.0
MAX -6379.0
PPP2R2A -6359.0
CCND2 -6290.0
SPC24 -6225.0
TUBGCP3 -6224.0
PSMC6 -6219.0
MCPH1 -6206.0
KIF2B -6144.0
AKAP9 -6138.0
SEC13 -6136.0
PSME2 -6132.0
H2BC14 -6126.0
CCNH -6119.0
NEK2 -6109.0
CDC26 -6099.0
ANAPC10 -6095.0
ACTR1A -6083.0
FBXW11 -6079.0
TUBA1A -6069.0
SDCCAG8 -6001.0
CCND3 -5993.0
SMC4 -5947.0
NUP155 -5935.0
ANAPC7 -5877.0
AURKA -5849.0
E2F5 -5820.0
PAFAH1B1 -5709.0
ITGB3BP -5665.0
LIG1 -5649.0
TNPO1 -5632.0
GSK3B -5572.0
PLK4 -5568.0
RAB1A -5565.0
GINS4 -5546.0
H3C2 -5478.0
HAUS3 -5461.0
TUBB2A -5397.0
HAUS4 -5369.0
SKA1 -5357.0
H2AC7 -5340.5
H2BC7 -5340.5
POLD3 -5331.0
POLD4 -5312.0
NUP153 -5310.0
POM121 -5300.0
TAOK1 -5276.0
CDK4 -5202.0
NCAPD2 -5155.0
CHMP6 -5085.0
RAB1B -5084.0
NDC80 -5070.0
CDKN1A -5005.0
CCP110 -4990.0
SGO2 -4989.0
CENPC -4957.0
ORC3 -4904.0
DHFR -4846.0
POLA2 -4771.0
LPIN2 -4698.0
KNL1 -4647.0
PSMB10 -4606.0
TUBB6 -4561.0
PPP1R12A -4556.0
XPO1 -4530.0
HMMR -4498.0
E2F3 -4451.0
CEP76 -4407.0
AKT1 -4393.0
PSMB2 -4344.0
DYNC1H1 -4301.0
CENPP -4279.0
PPP2R2D -4227.0
NCAPG2 -4222.0
CDC23 -4153.0
NUP188 -4141.0
RCC2 -4121.0
LYN -4113.0
CEP63 -4104.0
RCC1 -4097.0
CENPT -4073.0
PSMD7 -4057.0
TMPO -4027.0
CDC27 -4025.0
H4C4 -4007.0
TUBGCP2 -4000.0
NUP133 -3990.0
NDEL1 -3912.0
GINS1 -3910.0
MCM3 -3901.0
CENPO -3864.0
CHMP2A -3860.0
CKAP5 -3856.0
RFC5 -3853.0
MAU2 -3832.0
GOLGA2 -3802.0
LCMT1 -3786.0
H2BC21 -3732.0
GINS2 -3730.0
JAK2 -3714.0
PPP2R5E -3635.0
AKT3 -3595.0
H4C6 -3568.0
HAUS1 -3554.0
SFI1 -3534.0
KIF18A -3490.0
RPS27 -3484.0
TYMS -3420.0
PSMA7 -3416.0
H2AC14 -3377.0
DBF4 -3290.0
PSME3 -3245.0
MNAT1 -3244.0
SKP1 -3229.0
ESPL1 -3216.0
NCAPG -3211.0
PRKCB -3201.0
RFC1 -3189.0
TUBA1C -3186.0
NUP42 -3160.0
MCM8 -3130.0
DSN1 -3120.0
STAG1 -3119.0
H3C4 -3045.0
E2F4 -2971.0
CDC45 -2877.0
RFC4 -2868.0
AURKB -2861.0
HAUS8 -2836.0
RFC3 -2823.0
LIN9 -2792.0
PSMC4 -2787.0
CDK1 -2730.0
CCNA1 -2724.0
FBXO5 -2720.0
CKS1B -2712.0
SGO1 -2709.0
NUP98 -2703.0
PPP1R12B -2698.0
CENPL -2691.0
PMF1 -2655.0
USO1 -2632.0
CLASP1 -2556.0
TUBA8 -2524.0
NUP160 -2508.0
INCENP -2499.0
PPP2CB -2471.0
ORC4 -2389.0
CEP131 -2380.0
MCM2 -2330.0
HSP90AA1 -2213.0
CSNK2B -2185.0
SEM1 -2183.0
CHMP4C -2173.0
SPC25 -2166.0
DYNC1I1 -2149.0
CENPE -2121.0
AHCTF1 -2112.0
TUBB2B -2109.0
PDS5B -2101.0
ORC1 -2097.0
SUMO1 -2089.0
ANAPC5 -2079.0
MYC -2072.0
NUP35 -2059.0
DCTN1 -2023.0
CHMP3 -2000.0
PSMB6 -1996.0
CDC6 -1968.0
PSMD14 -1965.0
B9D2 -1934.0
MCM5 -1856.0
NUMA1 -1745.0
DYRK1A -1677.0
RAD21 -1610.0
KIF23 -1597.0
CSNK1D -1577.0
PLK1 -1530.0
LMNB1 -1456.0
PSMD9 -1453.0
PSMC5 -1352.0
SMC3 -1334.0
PPP2R5D -1303.0
PSMB4 -1200.0
H3C10 -1128.0
CCNE1 -1118.0
H4C12 -1092.0
SSNA1 -1082.0
ALMS1 -1048.0
KIF20A -1025.0
PSMA3 -989.0
TUBB -950.0
PRKACA -933.0
AAAS -910.0
CDKN1C -870.0
H4C2 -859.0
PSMC2 -840.0
TP53 -831.0
NUP37 -825.0
FOXM1 -789.0
POLE -777.0
CENPN -774.0
SKP2 -722.0
UBE2C -706.0
PSMD6 -684.0
CENPM -681.0
RANGAP1 -663.0
SET -625.0
MIS12 -582.0
ABL1 -558.0
PCNT -547.0
NUP43 -528.0
PSMD11 -524.0
ANAPC15 -493.0
NUP214 -489.0
PSMB1 -483.0
MCM4 -452.0
CEP57 -401.0
PSMA4 -398.0
TUBA3C -374.0
TUBGCP5 -373.0
MAD1L1 -288.0
VRK1 -268.0
MASTL -179.0
CABLES1 -149.0
TUBA3E -95.0
WEE1 -40.0
RBBP4 -33.0
TUBG1 -30.0
H2BC13 1.0
BUB1 3.0
UBE2S 7.0
CDC7 20.0
CDCA5 37.0
PSMD4 55.0
ANKLE2 78.0
CEP290 127.0
ORC5 201.0
NUP85 327.0
LIN37 339.0
PSMD12 373.0
PPP2R5C 395.0
E2F6 396.0
PPP1CC 455.0
CENPH 476.0
KPNB1 488.0
CEP152 501.0
PSMF1 550.0
GORASP2 630.0
IST1 734.0
PSMA2 776.0
UBE2I 794.0
BUB3 813.0
H3-4 835.0
ANAPC11 853.0
SIRT2 1014.0
WAPL 1021.0
NUP54 1027.0
EML4 1046.0
YWHAE 1068.0
PSMD3 1087.0
PSMB9 1093.0
CCND1 1122.0
ANAPC4 1161.0
CDT1 1167.0
SPAST 1221.0
ORC6 1225.0
RANBP2 1258.0
CDK11B 1301.0
UBB 1320.0
NUF2 1321.0
TUBGCP6 1346.0
MAPRE1 1433.0
H4C8 1444.0
RPA2 1570.0
H2BC26 1619.0
GMNN 1641.0
PPME1 1693.0
NUP88 1774.0
TOP2A 1778.0
RAN 1799.0
LEMD3 1803.0
GINS3 1818.0
PSMA5 1847.0
CDK7 1850.0
CHMP7 1896.0
PPP2R5A 1963.0
CEP192 1984.0
PSMB8 2004.0
NCAPH 2016.0
MCM6 2022.0
PPP2R1B 2037.0
POLD2 2071.0
RRM2 2113.0
NUP210 2136.0
BTRC 2163.0
PSMA1 2177.0
ANAPC16 2196.0
H2BC15 2203.0
TPX2 2214.0
RPS27A 2313.0
NUP107 2333.0
SKA2 2357.0
H2BC4 2363.0
LMNA 2364.0
CENPJ 2408.0
NDC1 2461.0
LPIN1 2580.0
H4C1 2583.0
PPP2CA 2625.0
DYNC1LI2 2640.0
UBA52 2643.0
PSMD8 2754.0
DNA2 2831.0
MZT2B 2863.0
VPS4A 2877.0
CENPS 2903.0
CDC20 2914.0
RFC2 2936.0
NCAPD3 2979.0
PRKCA 3022.0
PSME4 3100.0
FEN1 3104.0
POLE2 3141.0
PSMD1 3155.0
H2AC20 3179.0
CEP164 3190.0
CCNB1 3317.0
AJUBA 3376.0
MCM7 3530.0
GTSE1 3631.0
HAUS6 3637.0
TUBGCP4 3739.0
MCM10 3811.0
CENPU 3842.0
KIF2A 3843.0
SPDL1 3844.0
CDC25B 3854.0
KNTC1 3867.0
ARPP19 3901.0
RBL2 3958.0
CDC14A 3993.0
CENPF 4067.0
ESCO1 4095.0
H2BC17 4130.0
CC2D1B 4231.0
NIPBL 4313.0
ANAPC1 4318.0
NUP58 4456.0
ANAPC2 4548.0
PRKAR2B 4569.0
BANF1 4582.0
H2BC11 4657.0
PRIM2 4668.0
TUBA1B 4671.0
NEK6 4718.0
H3C1 4735.0
RPA3 4736.0
MYBL2 4741.0
PSMC1 4758.0
PPP1CB 4911.0
HDAC1 4949.0
PSMB3 5015.0
PKMYT1 5191.0
CCNA2 5235.0
POLD1 5363.0
CDK11A 5371.0
HAUS5 5396.0
H4C5 5401.0
H2AZ2 5485.0
TUBB1 5561.0
CEP250 5608.0
SRC 5689.0
PSMC3 5724.0
PSMB5 5798.0
AKT2 5824.0
PHLDA1 5853.0
MZT1 5950.0
CHMP4B 5954.0
POLE3 5980.0
CEP135 6155.0
ZW10 6165.0
PPP2R1A 6221.0
H2AC6 6426.0
CTDNEP1 6564.0
H2AX 6737.0
NUP205 6912.0
BORA 6945.0
UBE2D1 7063.0
RPA1 7064.0
E2F1 7131.0
TPR 7154.0
MAD2L1 7226.0
CDCA8 7291.0
CENPK 7336.0
BIRC5 7359.0
PTK6 7450.0
NUP62 7697.0
LEMD2 7754.0
DCTN3 7804.0
MAPK3 7947.0
NCAPH2 7983.0
PSMD2 8298.0
SEH1L 8440.0
LPIN3 8445.0
CDKN2D 8586.0
PSMA8 8939.0
DYNLL2 9125.0
NINL 9408.0
PSMB11 10222.0
TUBB8 10871.0



REACTOME_CELL_CYCLE

REACTOME_CELL_CYCLE
190
set REACTOME_CELL_CYCLE
setSize 666
pANOVA 2.24e-15
s.dist -0.18
p.adjustANOVA 4.09e-13



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708
H3C6 -10650
CSNK1E -10595
PSMB7 -10578
POM121C -10473
ANKRD28 -10373
POLR2C -10372
TUBA3D -10346
RMI2 -10267
DCTN2 -10239
BRCA2 -10235
YWHAG -10207
TUBB4B -10078
TUBG2 -10039
H4C3 -9942
LBR -9832
CSNK2A1 -9812
EP300 -9776
CCNE2 -9681
SMC2 -9640

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
H3C6 -10650.0
CSNK1E -10595.0
PSMB7 -10578.0
POM121C -10473.0
ANKRD28 -10373.0
POLR2C -10372.0
TUBA3D -10346.0
RMI2 -10267.0
DCTN2 -10239.0
BRCA2 -10235.0
YWHAG -10207.0
TUBB4B -10078.0
TUBG2 -10039.0
H4C3 -9942.0
LBR -9832.0
CSNK2A1 -9812.0
EP300 -9776.0
CCNE2 -9681.0
SMC2 -9640.0
CEP41 -9604.0
H2BC12 -9581.0
BLM -9563.0
UBC -9558.0
PSMD5 -9539.0
NBN -9502.0
H4C11 -9492.0
DYNLL1 -9489.0
H4C9 -9486.0
DYNC1LI1 -9445.0
H2BC5 -9371.0
NEK9 -9304.0
H3-3A -9260.0
CDC25C -9256.0
H4C16 -9179.0
TK1 -9168.0
RAB2A -9166.0
CHEK1 -9151.0
H2AC4 -9092.0
UBE2E1 -9071.0
KMT5A -9054.0
RAE1 -9026.0
CLIP1 -8978.0
E2F2 -8947.0
RAB8A -8934.0
HUS1 -8871.0
TINF2 -8864.0
FBXL18 -8861.0
CSNK2A2 -8850.0
CNEP1R1 -8817.0
TUBB4A -8809.0
CENPA -8800.0
RB1 -8767.0
PDS5A -8763.0
CHMP4A -8725.0
MAPK1 -8617.0
CDC16 -8598.0
NEK7 -8538.0
TFDP2 -8530.0
H2BC1 -8504.0
PPP2R5B -8503.0
HAUS2 -8502.0
NME7 -8404.0
H4C13 -8401.0
H3-3B -8363.0
PCM1 -8345.0
NSL1 -8302.0
CNTRL -8294.0
H3C8 -8260.0
H2BC3 -8237.0
CENPQ -8231.0
RBL1 -8170.0
TFDP1 -8155.0
CDC25A -8146.0
MZT2A -8124.0
H2BC8 -8108.0
PSME1 -8101.0
CDK6 -8085.0
RAD1 -8063.0
CDK2 -8046.0
PHF20 -8020.0
PSMA6 -7988.0
NDE1 -7893.0
PRIM1 -7890.0
TEN1 -7857.0
PCNA -7849.0
NUP50 -7820.0
NEDD1 -7817.0
KIF2C -7797.0
RBX1 -7781.0
ZWINT -7770.0
CCNB2 -7768.0
CDKN2A -7757.0
NUDC -7747.0
HSP90AB1 -7735.0
CDKN2B -7709.0
POLR2K -7697.0
H3C11 -7686.0
CEP72 -7656.0
NUP93 -7632.0
CDKN2C -7581.0
CEP43 -7565.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
POLE4 -7505.0
FZR1 -7430.0
H2AJ -7338.0
ESCO2 -7333.0
ENSA -7326.0
CHMP2B -7324.0
ATRIP -7316.0
PTTG1 -7296.0
ZWILCH -7287.0
POLR2A -7267.0
GORASP1 -7243.0
FKBPL -7151.0
ODF2 -7132.0
CEP78 -7050.0
OPTN -7047.0
CEP70 -7040.0
H2BC10 -6977.0
BUB1B -6938.0
H3C3 -6933.0
CUL1 -6904.0
TUBAL3 -6859.0
FBXL7 -6851.0
TUBA4A -6826.0
H3C12 -6825.0
BLZF1 -6782.0
ORC2 -6761.0
CDKN1B -6757.0
H2AC8 -6733.0
PSMC3IP -6654.0
LIN54 -6650.0
VRK2 -6642.0
CDK5RAP2 -6558.0
DYNC1I2 -6523.0
H2AC18 -6516.5
H2AC19 -6516.5
LIN52 -6507.0
TUBB3 -6481.0
TUBA4B -6407.0
PSMD13 -6393.0
CLASP2 -6389.0
MAX -6379.0
PPP2R2A -6359.0
YWHAH -6318.0
CCND2 -6290.0
SPC24 -6225.0
TUBGCP3 -6224.0
PSMC6 -6219.0
MCPH1 -6206.0
YWHAZ -6164.0
KIF2B -6144.0
AKAP9 -6138.0
SEC13 -6136.0
PSME2 -6132.0
H2BC14 -6126.0
CCNH -6119.0
NEK2 -6109.0
CDC26 -6099.0
ANAPC10 -6095.0
ACTR1A -6083.0
FBXW11 -6079.0
TUBA1A -6069.0
SDCCAG8 -6001.0
CCND3 -5993.0
SPO11 -5978.0
MLH3 -5957.0
SMC4 -5947.0
NUP155 -5935.0
ANAPC7 -5877.0
HSPA2 -5868.0
AURKA -5849.0
E2F5 -5820.0
BARD1 -5779.0
PAFAH1B1 -5709.0
CHTF18 -5681.0
MRE11 -5675.0
ITGB3BP -5665.0
LIG1 -5649.0
TNPO1 -5632.0
RNF8 -5619.0
ATM -5608.0
RBBP8 -5574.0
GSK3B -5572.0
PLK4 -5568.0
RAB1A -5565.0
GINS4 -5546.0
H3C2 -5478.0
HAUS3 -5461.0
TUBB2A -5397.0
HAUS4 -5369.0
SKA1 -5357.0
H2AC7 -5340.5
H2BC7 -5340.5
POLD3 -5331.0
POLD4 -5312.0
NUP153 -5310.0
POM121 -5300.0
TAOK1 -5276.0
CHEK2 -5211.0
CDK4 -5202.0
HJURP -5170.0
NCAPD2 -5155.0
CHMP6 -5085.0
RAB1B -5084.0
KAT5 -5079.0
NDC80 -5070.0
CDKN1A -5005.0
CCP110 -4990.0
SGO2 -4989.0
BABAM2 -4972.0
COP1 -4967.0
CENPC -4957.0
SYNE2 -4945.0
ATR -4921.0
ORC3 -4904.0
DHFR -4846.0
POLA2 -4771.0
TEX12 -4746.0
MND1 -4729.0
ABRAXAS1 -4723.0
LPIN2 -4698.0
KNL1 -4647.0
POT1 -4645.0
PSMB10 -4606.0
TUBB6 -4561.0
PPP1R12A -4556.0
XPO1 -4530.0
HMMR -4498.0
E2F3 -4451.0
CEP76 -4407.0
AKT1 -4393.0
PSMB2 -4344.0
DYNC1H1 -4301.0
CENPP -4279.0
PPP2R2D -4227.0
NCAPG2 -4222.0
CENPW -4209.0
CDC23 -4153.0
NUP188 -4141.0
RCC2 -4121.0
LYN -4113.0
CEP63 -4104.0
RCC1 -4097.0
CENPT -4073.0
PSMD7 -4057.0
TMPO -4027.0
CDC27 -4025.0
H4C4 -4007.0
TUBGCP2 -4000.0
NUP133 -3990.0
DSCC1 -3950.0
MSH4 -3914.0
NDEL1 -3912.0
GINS1 -3910.0
MCM3 -3901.0
CENPO -3864.0
CHMP2A -3860.0
CKAP5 -3856.0
RFC5 -3853.0
MAU2 -3832.0
GOLGA2 -3802.0
LCMT1 -3786.0
RUVBL1 -3783.0
H2BC21 -3732.0
GINS2 -3730.0
JAK2 -3714.0
GAR1 -3666.0
PPP2R5E -3635.0
NSD2 -3599.0
AKT3 -3595.0
H4C6 -3568.0
HAUS1 -3554.0
SFI1 -3534.0
KIF18A -3490.0
RPS27 -3484.0
UBE2N -3431.0
TYMS -3420.0
PSMA7 -3416.0
H2AC14 -3377.0
DBF4 -3290.0
RAD51 -3266.0
PSME3 -3245.0
MNAT1 -3244.0
SKP1 -3229.0
ESPL1 -3216.0
NCAPG -3211.0
PRKCB -3201.0
RFC1 -3189.0
TUBA1C -3186.0
NUP42 -3160.0
MCM8 -3130.0
DSN1 -3120.0
STAG1 -3119.0
TP53BP1 -3116.0
H3C4 -3045.0
E2F4 -2971.0
POLR2I -2893.0
CDC45 -2877.0
RFC4 -2868.0
AURKB -2861.0
HAUS8 -2836.0
RFC3 -2823.0
LIN9 -2792.0
PSMC4 -2787.0
CDK1 -2730.0
CCNA1 -2724.0
FBXO5 -2720.0
CKS1B -2712.0
SYCE2 -2711.0
SGO1 -2709.0
NUP98 -2703.0
PPP1R12B -2698.0
CENPL -2691.0
PMF1 -2655.0
USO1 -2632.0
POLR2B -2615.0
CLASP1 -2556.0
TUBA8 -2524.0
NUP160 -2508.0
INCENP -2499.0
RSF1 -2483.0
PPP2CB -2471.0
ORC4 -2389.0
CEP131 -2380.0
MCM2 -2330.0
UIMC1 -2261.0
HSP90AA1 -2213.0
CSNK2B -2185.0
SEM1 -2183.0
CHMP4C -2173.0
SPC25 -2166.0
DYNC1I1 -2149.0
CENPE -2121.0
AHCTF1 -2112.0
TUBB2B -2109.0
PDS5B -2101.0
ORC1 -2097.0
SUMO1 -2089.0
ANAPC5 -2079.0
RAD17 -2076.0
MYC -2072.0
NUP35 -2059.0
DCTN1 -2023.0
CHMP3 -2000.0
PSMB6 -1996.0
CHTF8 -1969.0
CDC6 -1968.0
PSMD14 -1965.0
DIDO1 -1943.0
B9D2 -1934.0
PRDM9 -1927.0
MCM5 -1856.0
BABAM1 -1800.0
MSH5 -1775.0
NUMA1 -1745.0
DYRK1A -1677.0
SMARCA5 -1620.0
RAD21 -1610.0
TERF1 -1604.0
KIF23 -1597.0
CSNK1D -1577.0
PLK1 -1530.0
LMNB1 -1456.0
PSMD9 -1453.0
EXO1 -1398.0
PPP6C -1377.0
PSMC5 -1352.0
SMC3 -1334.0
PPP2R5D -1303.0
POLR2G -1251.0
PSMB4 -1200.0
H3C10 -1128.0
CCNE1 -1118.0
RMI1 -1101.0
H4C12 -1092.0
MDM2 -1085.0
SSNA1 -1082.0
RHNO1 -1080.0
ALMS1 -1048.0
KIF20A -1025.0
RAD9B -1016.0
PSMA3 -989.0
TUBB -950.0
PRKACA -933.0
DMC1 -929.0
AAAS -910.0
CDKN1C -870.0
H4C2 -859.0
PSMC2 -840.0
TP53 -831.0
NUP37 -825.0
FOXM1 -789.0
POLE -777.0
CENPN -774.0
SKP2 -722.0
UBE2C -706.0
PSMD6 -684.0
CENPM -681.0
RANGAP1 -663.0
RTEL1 -657.0
SET -625.0
MIS12 -582.0
PIAS4 -575.0
ABL1 -558.0
PCNT -547.0
NUP43 -528.0
PSMD11 -524.0
ANAPC15 -493.0
NUP214 -489.0
RAD9A -486.0
PSMB1 -483.0
MCM4 -452.0
CEP57 -401.0
PSMA4 -398.0
TUBA3C -374.0
TUBGCP5 -373.0
MLH1 -367.0
MIS18A -310.0
MAD1L1 -288.0
VRK1 -268.0
MASTL -179.0
PCBP4 -174.0
CABLES1 -149.0
TUBA3E -95.0
MDM4 -86.0
WEE1 -40.0
RBBP4 -33.0
TUBG1 -30.0
YWHAQ -11.0
H2BC13 1.0
BUB1 3.0
UBE2S 7.0
CDC7 20.0
CDCA5 37.0
PSMD4 55.0
ANKLE2 78.0
TERF2IP 79.0
CEP290 127.0
ORC5 201.0
CTC1 240.0
NUP85 327.0
LIN37 339.0
PSMD12 373.0
ACD 384.5
PPP2R5C 395.0
E2F6 396.0
PPP1CC 455.0
BRCA1 456.0
CENPH 476.0
PPP6R3 477.0
KPNB1 488.0
CEP152 501.0
PSMF1 550.0
SYCP2 595.0
GORASP2 630.0
IST1 734.0
PSMA2 776.0
UBE2I 794.0
BUB3 813.0
H3-4 835.0
ANAPC11 853.0
SIRT2 1014.0
WAPL 1021.0
NUP54 1027.0
EML4 1046.0
YWHAE 1068.0
PSMD3 1087.0
PSMB9 1093.0
CCND1 1122.0
ANAPC4 1161.0
CDT1 1167.0
DAXX 1201.0
SPAST 1221.0
MDC1 1223.0
ORC6 1225.0
RANBP2 1258.0
CDK11B 1301.0
UBB 1320.0
NUF2 1321.0
TUBGCP6 1346.0
MAPRE1 1433.0
H4C8 1444.0
HERC2 1503.0
WRN 1553.0
WRAP53 1560.0
RPA2 1570.0
H2BC26 1619.0
GMNN 1641.0
PPME1 1693.0
SYCP3 1756.0
NUP88 1774.0
TOP2A 1778.0
YWHAB 1797.0
RAN 1799.0
LEMD3 1803.0
GINS3 1818.0
PSMA5 1847.0
CDK7 1850.0
MIS18BP1 1868.0
PIF1 1870.0
POLR2L 1891.0
CHMP7 1896.0
UBE2V2 1929.0
PPP2R5A 1963.0
CEP192 1984.0
PSMB8 2004.0
NCAPH 2016.0
MCM6 2022.0
PPP2R1B 2037.0
POLD2 2071.0
RRM2 2113.0
NUP210 2136.0
BTRC 2163.0
PSMA1 2177.0
ANAPC16 2196.0
H2BC15 2203.0
TPX2 2214.0
NPM1 2295.0
RPS27A 2313.0
NUP107 2333.0
SKA2 2357.0
H2BC4 2363.0
LMNA 2364.0
CENPJ 2408.0
NDC1 2461.0
LPIN1 2580.0
H4C1 2583.0
BRIP1 2607.0
PPP2CA 2625.0
DYNC1LI2 2640.0
UBA52 2643.0
PSMD8 2754.0
DNA2 2831.0
MZT2B 2863.0
VPS4A 2877.0
CENPS 2903.0
SHQ1 2910.0
CDC20 2914.0
RFC2 2936.0
NCAPD3 2979.0
PRKCA 3022.0
POLR2H 3091.0
PSME4 3100.0
FEN1 3104.0
POLE2 3141.0
PSMD1 3155.0
H2AC20 3179.0
CEP164 3190.0
CCNB1 3317.0
ZNF385A 3333.0
RUVBL2 3352.0
AJUBA 3376.0
MCM7 3530.0
GTSE1 3631.0
HAUS6 3637.0
TERF2 3655.0
POLR2F 3701.0
TUBGCP4 3739.0
MCM10 3811.0
CENPU 3842.0
KIF2A 3843.0
SPDL1 3844.0
CDC25B 3854.0
KNTC1 3867.0
ARPP19 3901.0
RBL2 3958.0
CDC14A 3993.0
SYNE1 4046.0
CENPF 4067.0
ESCO1 4095.0
H2BC17 4130.0
SUN1 4168.0
NOP10 4184.0
SMC1B 4210.0
TERT 4229.0
CC2D1B 4231.0
NIPBL 4313.0
ANAPC1 4318.0
POLR2E 4421.0
NUP58 4456.0
RNF168 4485.0
ANAPC2 4548.0
PRKAR2B 4569.0
BANF1 4582.0
H2BC11 4657.0
PRIM2 4668.0
TUBA1B 4671.0
NHP2 4683.0
NEK6 4718.0
H3C1 4735.0
RPA3 4736.0
TOPBP1 4738.0
MYBL2 4741.0
PSMC1 4758.0
SUN2 4841.0
PPP1CB 4911.0
SYCE1 4947.0
HDAC1 4949.0
PSMB3 5015.0
PKMYT1 5191.0
CCNA2 5235.0
POLD1 5363.0
CDK11A 5371.0
HAUS5 5396.0
H4C5 5401.0
H2AZ2 5485.0
RAD51C 5512.0
TUBB1 5561.0
CEP250 5608.0
SRC 5689.0
PSMC3 5724.0
PSMB5 5798.0
AKT2 5824.0
PHLDA1 5853.0
STN1 5854.0
TOP3A 5902.0
MZT1 5950.0
CHMP4B 5954.0
POLE3 5980.0
CEP135 6155.0
ZW10 6165.0
PPP2R1A 6221.0
H2AC6 6426.0
SYCP1 6537.0
CTDNEP1 6564.0
RAD50 6618.0
REC8 6702.0
H2AX 6737.0
NUP205 6912.0
BORA 6945.0
UBE2D1 7063.0
RPA1 7064.0
FKBP6 7089.0
E2F1 7131.0
TPR 7154.0
MAD2L1 7226.0
STAG3 7261.0
CDCA8 7291.0
CENPK 7336.0
BIRC5 7359.0
CLSPN 7366.0
SYCE3 7368.0
PTK6 7450.0
NUP62 7697.0
LEMD2 7754.0
DCTN3 7804.0
MAPK3 7947.0
NCAPH2 7983.0
POLR2D 8105.0
PSMD2 8298.0
SEH1L 8440.0
LPIN3 8445.0
CDKN2D 8586.0
PSMA8 8939.0
OIP5 9094.0
DYNLL2 9125.0
NINL 9408.0
SFN 10169.0
PSMB11 10222.0
POLR2J 10234.0
TEX15 10327.0
TUBB8 10871.0



REACTOME_CELLULAR_SENESCENCE

REACTOME_CELLULAR_SENESCENCE
503
set REACTOME_CELLULAR_SENESCENCE
setSize 189
pANOVA 1.67e-14
s.dist -0.323
p.adjustANOVA 2.75e-12



Top enriched genes

Top 20 genes
GeneID Gene Rank
MIR24-2 -10899
RPS6KA1 -10777
H2BC6 -10708
H3C6 -10650
ETS2 -10506
CXCL8 -10206
IL6 -10121
H1-0 -10051
AGO4 -9949
H4C3 -9942
CCNE2 -9681
H2BC12 -9581
UBC -9558
MAPKAPK3 -9529
NBN -9502
H4C11 -9492
H4C9 -9486
H2BC5 -9371
BMI1 -9287
H3-3A -9260

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MIR24-2 -10899.0
RPS6KA1 -10777.0
H2BC6 -10708.0
H3C6 -10650.0
ETS2 -10506.0
CXCL8 -10206.0
IL6 -10121.0
H1-0 -10051.0
AGO4 -9949.0
H4C3 -9942.0
CCNE2 -9681.0
H2BC12 -9581.0
UBC -9558.0
MAPKAPK3 -9529.0
NBN -9502.0
H4C11 -9492.0
H4C9 -9486.0
H2BC5 -9371.0
BMI1 -9287.0
H3-3A -9260.0
H4C16 -9179.0
MIR24-1 -9163.0
CBX6 -9157.0
TXN -9118.0
H2AC4 -9092.0
UBE2E1 -9071.0
E2F2 -8947.0
TINF2 -8864.0
CBX8 -8780.0
RB1 -8767.0
H1-3 -8667.0
MAPK1 -8617.0
CDC16 -8598.0
MAP3K5 -8582.0
TFDP2 -8530.0
H2BC1 -8504.0
MAP2K6 -8430.0
H4C13 -8401.0
HMGA2 -8387.0
H3-3B -8363.0
PHC3 -8272.0
H3C8 -8260.0
H2BC3 -8237.0
TFDP1 -8155.0
H2BC8 -8108.0
CDK6 -8085.0
CDK2 -8046.0
PHC1 -7771.0
CDKN2A -7757.0
MAPKAPK2 -7751.0
CDKN2B -7709.0
H3C11 -7686.0
AGO3 -7679.0
EZH2 -7675.0
CDKN2C -7581.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
TNRC6B -7491.0
FZR1 -7430.0
H2AJ -7338.0
UBN1 -7049.0
MINK1 -7041.0
EED -7009.0
H2BC10 -6977.0
H3C3 -6933.0
CEBPB -6830.0
H3C12 -6825.0
CDKN1B -6757.0
H2AC8 -6733.0
H2AC18 -6516.5
H2AC19 -6516.5
ID1 -6322.0
MAPKAPK5 -6287.0
H2BC14 -6126.0
CDC26 -6099.0
ANAPC10 -6095.0
AGO1 -6050.0
SP1 -5960.0
RNF2 -5882.0
ANAPC7 -5877.0
MRE11 -5675.0
ATM -5608.0
VENTX -5482.0
H3C2 -5478.0
CBX2 -5379.0
H2AC7 -5340.5
H2BC7 -5340.5
CDK4 -5202.0
KAT5 -5079.0
CDKN1A -5005.0
ETS1 -4955.0
POT1 -4645.0
STAT3 -4580.0
MOV10 -4504.0
E2F3 -4451.0
TNRC6C -4438.0
MAPK14 -4437.0
MAPK9 -4226.0
CDC23 -4153.0
MAP2K7 -4122.0
CDC27 -4025.0
H4C4 -4007.0
TNIK -3843.0
HMGA1 -3826.0
H2BC21 -3732.0
RELA -3661.0
MAPK7 -3657.0
H4C6 -3568.0
H2AC14 -3377.0
H1-2 -3287.0
KDM6B -3253.0
EHMT2 -3061.0
H3C4 -3045.0
MAP2K4 -2820.0
CCNA1 -2724.0
ERF -2621.0
EP400 -2470.0
H1-4 -2279.0
ANAPC5 -2079.0
MAP2K3 -1752.0
TERF1 -1604.0
H1-5 -1539.0
LMNB1 -1456.0
PHC2 -1440.0
IGFBP7 -1265.0
H3C10 -1128.0
CCNE1 -1118.0
EHMT1 -1095.0
H4C12 -1092.0
MDM2 -1085.0
RING1 -863.0
H4C2 -859.0
TP53 -831.0
UBE2C -706.0
ANAPC15 -493.0
NFKB1 -285.0
MDM4 -86.0
RBBP4 -33.0
SCMH1 -17.0
H2BC13 1.0
UBE2S 7.0
TERF2IP 79.0
ACD 384.5
FOS 612.0
H3-4 835.0
ANAPC11 853.0
ANAPC4 1161.0
H1-1 1304.0
UBB 1320.0
H4C8 1444.0
H2BC26 1619.0
TNRC6A 1957.0
ANAPC16 2196.0
H2BC15 2203.0
RPS27A 2313.0
H2BC4 2363.0
ASF1A 2389.0
H4C1 2583.0
UBA52 2643.0
IFNB1 2718.0
CBX4 2785.0
MAPK10 2866.0
JUN 3045.0
H2AC20 3179.0
MAP4K4 3287.0
CABIN1 3355.0
MAPK8 3520.0
TERF2 3655.0
HIRA 3863.0
H2BC17 4130.0
RPS6KA2 4142.0
ANAPC1 4318.0
ANAPC2 4548.0
H2BC11 4657.0
H3C1 4735.0
CCNA2 5235.0
H4C5 5401.0
H2AZ2 5485.0
SUZ12 5843.0
H2AC6 6426.0
RAD50 6618.0
H2AX 6737.0
UBE2D1 7063.0
E2F1 7131.0
MAPK3 7947.0
CDKN2D 8586.0
MAPK11 8999.0
IL1A 10212.0



REACTOME_INNATE_IMMUNE_SYSTEM

REACTOME_INNATE_IMMUNE_SYSTEM
227
set REACTOME_INNATE_IMMUNE_SYSTEM
setSize 1002
pANOVA 2.26e-13
s.dist -0.137
p.adjustANOVA 3.37e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
FOLR3 -11001
AZU1 -11000
MPO -10991
FCGR3B -10986
TYROBP -10977
S100A8 -10967
HP -10960
MS4A3 -10959
FCER1G -10931
LRG1 -10874
ELANE -10873
PRTN3 -10865
ICAM2 -10854
S100P -10845
VAT1 -10828
RNASE2 -10824
TLR4 -10819
P2RX1 -10816
FGR -10813
STING1 -10809

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FOLR3 -11001.0
AZU1 -11000.0
MPO -10991.0
FCGR3B -10986.0
TYROBP -10977.0
S100A8 -10967.0
HP -10960.0
MS4A3 -10959.0
FCER1G -10931.0
LRG1 -10874.0
ELANE -10873.0
PRTN3 -10865.0
ICAM2 -10854.0
S100P -10845.0
VAT1 -10828.0
RNASE2 -10824.0
TLR4 -10819.0
P2RX1 -10816.0
FGR -10813.0
STING1 -10809.0
IFNA2 -10803.0
RNASE3 -10798.0
CTSG -10796.0
OSCAR -10785.0
RPS6KA1 -10777.0
UBA7 -10772.0
CDA -10763.0
TARM1 -10741.0
CEACAM3 -10740.0
CD300LB -10737.0
BIN2 -10733.0
ADGRG3 -10728.0
CTSD -10727.0
DEFA4 -10705.0
BRI3 -10690.0
SIGLEC9 -10673.0
RETN -10664.0
IRAK3 -10649.0
IL1B -10628.0
RHOG -10627.0
RNASE7 -10610.0
NOD1 -10608.0
PSMB7 -10578.0
NLRC4 -10566.0
CD63 -10554.0
C3AR1 -10553.0
COMMD3 -10537.0
ATP6V0A1 -10535.0
OLR1 -10525.0
PLAC8 -10491.0
CYB5R3 -10489.0
SLPI -10488.0
NLRP3 -10484.0
CTSZ -10474.0
PRKACG -10472.0
PLAU -10466.0
SIRPB1 -10398.0
S100A9 -10359.0
TREM1 -10354.0
HSPA1B -10332.0
CEACAM6 -10315.0
PRKCD -10313.0
TLR6 -10302.0
CLEC4A -10285.0
PYCARD -10282.0
BST2 -10269.0
CLEC7A -10243.0
CLEC12A -10222.0
CD59 -10212.0
CASP10 -10209.0
ADGRE3 -10199.0
FCAR -10188.0
DUSP3 -10152.0
UNC13D -10148.0
CDC42 -10147.0
S100A11 -10117.0
PPP3R1 -10110.0
PRG3 -10090.0
TUBB4B -10078.0
STOM -10067.0
NOD2 -10042.0
TNFAIP6 -10036.0
SHC1 -10031.0
CEACAM8 -10013.0
C5AR2 -10000.0
TREX1 -9978.0
PGLYRP2 -9960.0
TLR10 -9939.0
PLD1 -9920.0
ITPR1 -9913.0
ARMC8 -9901.0
MAP2K1 -9899.0
AHCYL1 -9882.0
ADGRE5 -9881.0
FCGR3A -9874.0
SELL -9837.0
LIMK1 -9824.0
POLR3K -9815.0
PLEKHO2 -9793.0
TLR1 -9777.0
EP300 -9776.0
LAIR1 -9770.0
OSTF1 -9768.0
LYZ -9758.0
SLC15A4 -9739.0
GHDC -9717.0
CLU -9690.0
NFATC2 -9680.0
CPB2 -9674.0
ATP6V1E2 -9669.0
SFTPD -9655.0
IQGAP2 -9572.0
UBC -9558.0
PSMD5 -9539.0
TRIM4 -9532.0
MAPKAPK3 -9529.0
ARG1 -9527.0
PIK3C3 -9526.0
RAC1 -9520.0
RAB3D -9518.0
STBD1 -9490.0
DYNLL1 -9489.0
WASL -9476.0
SLCO4C1 -9467.0
CREG1 -9464.0
DYNC1LI1 -9445.0
MGST1 -9423.0
PIK3R1 -9422.0
ATP6V0E2 -9413.0
CTSA -9402.0
SIGIRR -9395.0
DBNL -9369.0
ENPP4 -9368.0
ATP6V1A -9350.0
DNAJC3 -9320.0
TICAM2 -9315.0
GMFG -9293.0
SERPINB1 -9266.0
NCKAP1L -9254.0
TRAF6 -9223.0
YES1 -9222.0
ATP6V0A2 -9218.0
MCEMP1 -9192.0
AMPD3 -9178.0
MAP3K8 -9174.0
VAV1 -9126.0
TXN -9118.0
HSPA8 -9110.0
RAB3A -9107.0
TMEM30A -9103.0
ATP6V0B -9091.0
UBE2L6 -9089.0
GSTP1 -9087.0
SIGLEC15 -9075.0
FPR2 -9070.0
SVIP -9060.0
NLRP1 -9036.0
MEFV -9034.0
RPS6KA5 -9028.0
PRDX6 -8994.0
RAB18 -8986.0
B4GALT1 -8905.0
GZMM -8891.0
CD177 -8883.0
VAMP8 -8876.0
CASP1 -8859.0
KRAS -8798.0
DOK3 -8784.0
CANT1 -8765.0
CASP2 -8729.0
CMTM6 -8713.0
TBK1 -8689.0
LAT2 -8688.0
ISG15 -8683.0
NKIRAS2 -8682.0
RAB14 -8674.0
TSPAN14 -8661.0
LPO -8642.0
MAPK1 -8617.0
PIK3CB -8584.0
TMBIM1 -8583.0
ATP6V1B2 -8528.0
FCN3 -8506.0
DNAJC5 -8494.0
CLEC5A -8483.0
TXNIP -8480.0
MAP2K6 -8430.0
DNM3 -8428.0
FTH1 -8414.0
RBSN -8410.0
CALM1 -8399.0
VCL -8392.0
FLG2 -8382.0
ADAM8 -8366.0
ATP6V0C -8341.0
KCMF1 -8335.0
WASF2 -8328.0
PKM -8326.0
ATP6V0E1 -8311.0
TAB2 -8307.0
PRG2 -8296.0
RNF125 -8189.0
LCN2 -8186.0
CDC34 -8176.0
GLIPR1 -8109.0
APRT -8105.0
PSME1 -8101.0
IRAG2 -8070.0
GM2A -8050.0
C8A -8008.0
NRAS -7996.0
PSMA6 -7988.0
PRKACB -7972.0
CD58 -7963.0
MNDA -7950.0
SLC2A3 -7911.0
CD68 -7905.0
BIRC3 -7850.0
ACP3 -7830.0
EEA1 -7816.0
GUSB -7796.0
CFD -7790.0
PLAUR -7776.0
IRF3 -7758.0
MAPKAPK2 -7751.0
RIPK3 -7739.0
HSP90AB1 -7735.0
GAB2 -7722.0
CXCL1 -7715.0
POLR2K -7697.0
PNP -7666.0
CAND1 -7637.0
ILF2 -7594.0
HPSE -7551.0
NHLRC3 -7545.0
CTSS -7536.0
GSN -7530.0
SURF4 -7475.0
NCF2 -7461.0
IMPDH1 -7445.0
DEFB104A -7410.5
DEFB104B -7410.5
C5AR1 -7405.0
HSPA1A -7384.0
TMEM179B -7378.0
PSAP -7355.0
WIPF1 -7342.0
HLA-A -7308.0
VNN1 -7295.0
GCA -7259.0
RIPK2 -7234.0
MEF2C -7222.0
AGPAT2 -7199.0
MAP3K1 -7185.0
CR1 -7165.0
DNM2 -7164.0
PPP3CA -7160.0
PTPRJ -7131.0
ATP8B4 -7120.0
CPNE3 -7119.0
AAMP -7090.0
LILRB2 -7077.0
NFATC3 -7058.0
RNASE6 -7042.0
TRAF2 -7035.0
PGM2 -7033.0
TMEM63A -7019.0
PRCP -6998.0
CTSB -6962.0
GGH -6932.0
ATP6V1E1 -6928.0
ADAM10 -6926.0
CUL1 -6904.0
TANK -6902.0
TAX1BP1 -6882.0
REG3G -6876.0
SNAP23 -6823.0
BRK1 -6818.0
DPP7 -6768.0
DEFB121 -6729.0
ELMO1 -6692.0
USP14 -6691.0
UBE2M -6686.0
PELI1 -6633.0
FTL -6608.0
TIMP2 -6599.0
PLD2 -6571.0
CASP9 -6532.0
PRKCQ -6522.0
LPCAT1 -6521.0
PLPP5 -6491.0
RAB27A -6480.0
NIT2 -6456.0
PSMD13 -6393.0
RAB37 -6372.0
TEC -6354.0
FUCA1 -6344.0
RAF1 -6328.0
FCGR2A -6280.0
MYO9B -6250.0
PSMC6 -6219.0
TRPM2 -6213.0
POLR3G -6201.0
CAPN1 -6158.0
DEFB125 -6146.0
PSME2 -6132.0
RAB31 -6084.0
FBXW11 -6079.0
PLD3 -6076.0
QPCT -6054.0
MYH2 -6047.0
RAB10 -5924.0
UBE2K -5898.0
SEMG1 -5845.0
IKBKB -5839.0
CPPED1 -5809.0
ALDOA -5782.0
CGAS -5760.0
RASGRP2 -5743.0
CD300E -5732.0
ATAD3B -5719.0
PADI2 -5691.0
ZBP1 -5676.0
MRE11 -5675.0
ACTR2 -5655.0
IFI16 -5651.0
CRCP -5650.0
P2RX7 -5641.0
CKAP4 -5628.0
TREM2 -5615.0
SERPINB10 -5601.0
ATP6V1G1 -5563.0
MAPK13 -5561.0
ATG7 -5557.0
TNFRSF1B -5497.0
APP -5475.0
HGSNAT -5473.0
PIK3CA -5472.0
RAP1B -5468.0
RHOA -5450.0
MAP3K7 -5435.0
CFHR4 -5433.0
NCR2 -5395.0
ROCK1 -5392.0
PTX3 -5365.0
ITPR2 -5260.0
TRIM32 -5248.0
CDK13 -5194.0
RAB7A -5134.0
ARSB -5118.0
CAB39 -5099.0
IFNA21 -5061.0
VAPA -5047.0
ACTG1 -5045.0
CYLD -4946.0
PLA2G6 -4913.0
SERPINB6 -4895.0
HSPA6 -4892.0
HCK -4883.0
CTSL -4854.0
NFKBIA -4831.0
IDH1 -4830.0
CFL1 -4824.0
PSTPIP1 -4810.0
PTPRC -4703.0
MAN2B1 -4700.0
VCP -4679.0
POLR3GL -4674.0
MALT1 -4653.0
LAMTOR2 -4633.0
PROS1 -4616.0
PSMB10 -4606.0
POLR1D -4579.0
NCSTN -4519.0
LILRA3 -4516.0
MAPK14 -4437.0
CPNE1 -4432.0
IFIH1 -4395.0
STK10 -4389.0
YPEL5 -4385.0
ACLY -4355.0
PSMB2 -4344.0
LAMTOR3 -4343.0
DYNC1H1 -4301.0
HEBP2 -4298.0
DNAJC13 -4296.0
CYSTM1 -4291.0
IKBIP -4269.0
POLR3D -4233.0
MAPK9 -4226.0
GRB2 -4184.0
RIPK1 -4183.0
CLEC4C -4182.0
MAP2K7 -4122.0
LYN -4113.0
PIK3R2 -4094.0
C6 -4061.0
RNASE8 -4060.0
PSMD7 -4057.0
CASP8 -4047.0
DEGS1 -4044.0
TLR3 -4026.0
STAT6 -4019.0
SDCBP -3961.0
SCAMP1 -3932.0
CHUK -3913.0
GPI -3859.0
DHX58 -3806.0
ERP44 -3774.0
TOMM70 -3759.0
MUC12 -3738.0
SLC11A1 -3723.0
UBE2D2 -3692.0
PANX1 -3673.0
RELA -3661.0
MAPK7 -3657.0
DIAPH1 -3654.0
PGM1 -3615.0
HERC5 -3591.0
ARPC3 -3530.0
CRACR2A -3491.0
MLEC -3475.0
UBE2N -3431.0
PSMA7 -3416.0
RHOF -3411.0
PIN1 -3401.0
IGF2R -3375.0
LTF -3357.0
ORMDL3 -3349.0
PPIA -3347.0
COPB1 -3302.0
ATP6V1D -3291.0
ASAH1 -3281.0
PGLYRP1 -3246.0
PSME3 -3245.0
SKP1 -3229.0
ATP6V1F -3217.0
ITCH -3210.0
ABI2 -3209.0
STK11IP -3207.0
DSN1 -3120.0
POLR3C -3112.0
AP1M1 -3083.0
ANO6 -3062.0
CLEC4D -3027.0
ALAD -2979.0
DERA -2963.0
C4BPA -2944.0
DUSP6 -2921.0
NCK1 -2917.0
ARPC1B -2913.0
CAT -2898.0
SIGLEC5 -2895.0
DUSP7 -2894.0
MAP3K14 -2885.0
MAP2K4 -2820.0
RAB5B -2791.0
RNF216 -2788.0
PSMC4 -2787.0
C6orf120 -2782.0
RAB24 -2776.0
APAF1 -2771.0
GNS -2689.0
CAPZA2 -2683.0
NCF4 -2678.0
NCKAP1 -2620.0
CST3 -2614.0
KLRD1 -2610.0
PIK3R4 -2533.0
ATP6V1C1 -2518.0
FABP5 -2493.0
APOB -2485.0
PPP2CB -2471.0
CD14 -2462.0
CFH -2461.0
ATG5 -2446.0
UBA3 -2439.0
BCL10 -2415.0
DUSP4 -2390.0
PGAM1 -2336.0
ATP6V1H -2333.0
LY96 -2317.0
PTPN11 -2297.0
ARPC5 -2287.0
ACTR3 -2275.0
HSP90AA1 -2213.0
A1BG -2204.0
SPTAN1 -2199.0
LAMTOR1 -2197.0
CSNK2B -2185.0
SEM1 -2183.0
AGL -2161.0
SARM1 -2134.0
PRKCE -2126.0
PTAFR -2007.0
HEXB -2003.0
PSMB6 -1996.0
VAV3 -1981.0
PSMD14 -1965.0
NOS3 -1936.0
NKIRAS1 -1882.0
NME2 -1778.0
LGMN -1758.0
MAP2K3 -1752.0
ALDH3B1 -1747.0
ITGAL -1703.0
TNFAIP3 -1669.0
PELI2 -1615.0
TXNDC5 -1573.0
PSMD9 -1453.0
CAPZA1 -1452.0
HSP90B1 -1447.0
ORM1 -1431.0
PPP3CB -1418.0
SRP14 -1415.0
ATP8A1 -1404.0
HVCN1 -1383.0
PSMC5 -1352.0
SIKE1 -1330.0
GPR84 -1328.0
DHX36 -1324.0
PPP2R5D -1303.0
DSG1 -1295.0
TRIM25 -1291.0
VTN -1281.0
GSDMD -1236.0
GDI2 -1214.0
ANXA2 -1205.0
PSMB4 -1200.0
DYNLT1 -1121.0
HRAS -1109.0
VRK3 -1033.0
PCBP2 -993.0
PSMA3 -989.0
CCT2 -979.0
RAB6A -961.0
TUBB -950.0
PRKACA -933.0
FADD -903.0
ALOX5 -896.0
RAC2 -876.0
MUC6 -873.0
PAK1 -872.0
FYN -844.0
PSMC2 -840.0
TP53 -831.0
UBR4 -782.0
PLCG2 -757.0
CFB -756.0
PSMD6 -684.0
TCIRG1 -659.0
CPN2 -626.0
ITGAM -621.0
ATOX1 -617.0
XRCC5 -615.0
TOLLIP -613.0
ABL1 -558.0
PSMD11 -524.0
CAP1 -499.0
PSMB1 -483.0
NLRX1 -476.0
ACTB -471.0
HMGB1 -457.0
POLR1C -455.0
PFKL -403.0
PSMA4 -398.0
HRNR -302.0
NFKB1 -285.0
PDXK -259.0
PECAM1 -258.0
SLC2A5 -235.0
NF2 -142.0
ATF1 -137.0
SNAP25 -90.0
CASP4 -23.0
PSMD4 55.0
RAB4B 70.0
HMOX2 98.0
PAK2 116.0
CEP290 127.0
IQGAP1 143.0
CYBA 145.0
UBE2V1 163.0
BCL2L1 175.0
MUC3A 176.0
MAVS 190.0
WIPF3 290.0
RAP1A 316.0
RELB 332.0
MUC13 348.0
CARD11 349.0
XRCC6 352.0
PSMD12 373.0
MUC15 411.0
HLA-C 426.0
ATP11B 431.0
LRRC14 452.0
FUCA2 472.0
KPNB1 488.0
CD47 496.0
CR2 544.0
PSMF1 550.0
BCL2 594.0
RASGRP1 608.0
FOS 612.0
ATP6V1G2 619.0
RAB5C 623.0
TICAM1 624.0
N4BP1 631.0
C4A 659.5
C4B 659.5
PAFAH1B2 687.0
ITGAV 688.0
MVP 690.0
PRKDC 733.0
IST1 734.0
MUC5B 741.0
CPN1 757.0
PSMA2 776.0
LGALS3 781.0
ITLN1 809.0
MUC1 810.0
ATF2 857.0
LCP2 880.0
ELMO2 918.0
KLRK1 922.0
NPC2 934.0
AGER 960.0
COLEC11 966.0
ARSA 989.0
DOCK2 995.0
HK3 1022.0
PSMD3 1087.0
PDPK1 1090.0
PSMB9 1093.0
ADA2 1098.0
POLR3E 1102.0
ARPC4 1111.0
CEACAM1 1152.0
CRISPLD2 1165.0
NCKIPSD 1183.0
GRN 1219.0
MMP9 1241.0
TRIM56 1255.0
CARD9 1262.0
QSOX1 1274.0
NEU1 1282.0
UBB 1320.0
GOLGA7 1326.0
KCNAB2 1328.0
CNPY3 1359.0
HTN1 1368.0
ARPC2 1448.0
TRAPPC1 1479.0
LRRFIP1 1482.0
GYG1 1486.0
NOS1 1499.0
UBE2D3 1527.0
DTX4 1691.0
GALNS 1741.0
MEF2A 1768.0
SYK 1786.0
DEFB118 1802.0
IFNA14 1841.0
PSMA5 1847.0
CCL17 1890.0
POLR2L 1891.0
CD209 1934.0
TOM1 1972.0
AP2A2 1989.0
SOS1 1990.0
MMP25 2001.0
PSMB8 2004.0
PPP2R1B 2037.0
S100B 2063.0
KRT1 2065.0
PYGL 2073.0
MANBA 2080.0
CTSC 2104.0
MYO1C 2134.0
PPIE 2138.0
BTRC 2163.0
PSMA1 2177.0
RNASET2 2184.0
CREB1 2212.0
PTPRB 2226.0
ARL8A 2270.0
PTPN6 2285.0
AGA 2299.0
EEF2 2310.0
RPS27A 2313.0
CTNNB1 2329.0
PSEN1 2391.0
NFKBIB 2446.0
MYD88 2451.0
DEFB113 2455.0
NFKB2 2472.0
S100A12 2532.0
UNC93B1 2613.0
PPP2CA 2625.0
RASGRP4 2628.0
NDUFC2 2637.0
TCN1 2641.0
UBA52 2643.0
SLC44A2 2692.0
IFNB1 2718.0
USP18 2744.0
PSMD8 2754.0
IRAK4 2781.0
MAPK10 2866.0
CD81 2892.0
TLR9 2952.0
ACAA1 2975.0
PTPRN2 3031.0
JUN 3045.0
EEF1A1 3054.0
DEFB134 3084.0
POLR2H 3091.0
NLRP4 3092.0
PSME4 3100.0
POLR3H 3139.0
PRKCSH 3152.0
PSMD1 3155.0
ATP6V1B1 3158.0
APEH 3165.0
TKFC 3169.0
MAPK12 3171.0
WASF1 3177.0
CD33 3238.0
GSDME 3256.0
CYFIP2 3267.0
B2M 3334.0
CCR2 3349.0
C1orf35 3357.0
EPX 3443.0
RAP2B 3449.0
CNN2 3453.0
TBC1D10C 3455.0
ITGAX 3467.0
MAPK8 3520.0
ATG12 3578.0
ABCA13 3603.0
PPBP 3636.0
IRAK2 3641.0
SERPING1 3657.0
PRSS3 3689.0
LTA4H 3700.0
POLR2F 3701.0
PTK2 3709.0
CXCR2 3747.0
PDAP1 3751.0
C3 3779.0
ATP11A 3806.0
TRAF3 3882.0
C1QC 3946.0
ITK 3947.0
CCT8 3952.0
DHX9 3953.0
IRF7 3976.0
DGAT1 3992.0
TIRAP 4018.0
CD44 4031.0
RPS6KA2 4142.0
FCN1 4162.0
POLR3B 4181.0
CTSH 4226.0
NFAM1 4271.0
RNF135 4294.0
ACTR1B 4339.0
PTPN4 4351.0
POLR2E 4421.0
MYH9 4460.0
SOCS1 4538.0
CD247 4556.0
IFNA8 4593.0
TLR2 4622.0
DSP 4643.0
ITGB2 4649.0
REG3A 4656.0
CD300A 4727.0
PSMC1 4758.0
CD55 4766.0
DDX41 4783.0
CD46 4784.0
NBEAL2 4785.0
CRISP3 4791.0
COMMD9 4852.0
CFI 4933.0
MYO5A 4951.0
DEFA6 4957.0
IFNA13 4961.0
PSMB3 5015.0
HLA-B 5059.0
POLR3A 5121.0
NLRC3 5139.0
SIGLEC14 5164.0
HMOX1 5202.0
SUGT1 5210.0
DEFB126 5223.0
BPIFB4 5225.0
TIFA 5267.0
FCER1A 5302.0
CFHR5 5313.0
C1R 5315.0
AOC1 5360.0
ABI1 5365.0
ATP6V0D2 5393.0
DEFB116 5394.0
ITPR3 5421.0
ALPK1 5431.0
ATP6V0D1 5442.0
PGLYRP4 5489.0
DEFB133 5502.0
FAF2 5547.0
VPS35L 5552.0
ICAM3 5569.0
NFATC1 5572.0
CRK 5590.0
MASP2 5613.0
SRC 5689.0
POLR3F 5693.0
PSMC3 5724.0
CREBBP 5734.0
NLRC5 5748.0
GLB1 5752.0
TAB1 5784.0
PSMB5 5798.0
RIGI 5819.0
FRK 5873.0
CHIT1 5895.0
MUC20 5948.0
RAB44 5981.0
F2 5998.0
SYNGR1 6014.0
ATP6V0A4 6044.0
ARHGAP9 6082.0
CTSV 6149.0
TLR5 6202.0
LRRC7 6207.0
PPP2R1A 6221.0
DEFB127 6233.0
DNM1 6255.0
C5 6262.0
FGL2 6305.0
DEFB119 6366.0
CD36 6422.0
C1S 6443.0
S100A7A 6449.0
ACTR10 6469.0
NOS2 6481.0
BPIFB2 6511.0
MGAM 6542.0
BST1 6562.0
SERPINA3 6571.0
C7 6598.0
PELI3 6599.0
HLA-E 6601.0
IMPDH2 6606.0
C9 6638.0
ATP6V1C2 6655.0
BPI 6662.0
GNLY 6712.0
MYO10 6725.0
BAIAP2 6744.0
MUC7 6748.0
SIRPA 6749.0
DOCK1 6775.0
ARPC1A 6795.0
BPIFB6 6810.0
CHGA 6827.0
DEFB1 6842.0
SERPINA1 6864.0
CTSK 6865.0
MUCL1 6913.0
CLEC10A 6922.0
CAMP 6935.0
ARHGAP45 6940.0
FGG 7005.0
COTL1 7010.0
CD4 7022.0
DEFB123 7037.0
UBE2D1 7063.0
TMC6 7073.0
CLEC6A 7077.0
COLEC10 7078.0
BIRC2 7080.0
WASF3 7143.0
BPIFA1 7164.0
MIF 7208.0
PLCG1 7235.0
DEFB115 7239.0
MUC21 7244.0
DEFB132 7357.0
CD53 7437.0
NAPRT 7508.0
DEFB129 7517.0
GAA 7596.0
LAMP1 7641.0
MUC17 7650.0
FGA 7652.0
MUC4 7673.0
PLD4 7701.0
IKBKE 7715.0
CYFIP1 7726.0
PLA2G2A 7757.0
AIM2 7777.0
DDOST 7801.0
PA2G4 7837.0
HTN3 7849.0
ATP6V1G3 7885.0
SNAP29 7925.0
CHRNB4 7941.0
MAPK3 7947.0
NFASC 7989.0
PLPP4 8083.0
LILRB3 8127.0
DEFB124 8229.0
LEAP2 8230.0
GRAP2 8240.0
ANPEP 8250.0
LAT 8286.0
PSMD2 8298.0
OLFM4 8324.0
TNIP2 8347.0
LBP 8377.0
CHI3L1 8418.0
HBB 8442.0
CXCR1 8450.0
FGB 8489.0
WIPF2 8508.0
ORM2 8524.0
MMP8 8545.0
DSC1 8552.0
CD93 8597.0
FPR1 8655.0
IFNA7 8666.0
JUP 8673.0
C8G 8690.0
DEFB114 8716.0
VAV2 8721.0
PGLYRP3 8776.0
SLC27A2 8790.0
IFNA1 8879.0
C8B 8885.0
CLEC4E 8889.0
PYGB 8921.0
PSMA8 8939.0
IFNA5 8942.0
MAPK11 8999.0
BPIFB1 9092.0
EPPIN 9200.0
C2 9220.0
TXK 9248.0
MME 9262.0
ECSIT 9274.0
AHSG 9334.0
C1QB 9365.0
IFNA16 9377.0
MUC16 9470.0
MS4A2 9503.0
PI3 9507.0
C1QA 9516.0
SFTPA2 9518.0
SERPINB3 9529.0
IFNA6 9549.0
MASP1 9581.0
S100A7 9601.0
DEFB136 9608.0
CCR6 9628.0
DEFB128 9665.0
TRIM21 9666.0
ALDOC 9669.0
PIGR 9711.0
CD180 9755.0
TTR 9756.0
BPIFA2 9797.0
PTGES2 9800.0
CSTB 9838.0
DEFB135 9902.0
LY86 9967.0
EPPIN-WFDC6 9978.0
S100A1 9998.0
LCK 10052.0
PKP1 10060.0
DEFB110 10105.0
SERPINB12 10122.0
MUC5AC 10125.0
DEFA5 10195.0
PSMB11 10222.0
CRP 10226.0
DCD 10300.0
ART1 10356.0
CD19 10506.0
CALML5 10619.0
CCL22 10712.0
FCN2 10726.0
SFTPA1 10742.0
C4BPB 10838.0
MBL2 10846.0
CFHR2 10864.0
SAA1 10902.0
CD3G 10960.0



REACTOME_M_PHASE

REACTOME_M_PHASE
1096
set REACTOME_M_PHASE
setSize 398
pANOVA 2.37e-12
s.dist -0.205
p.adjustANOVA 3.24e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708
H3C6 -10650
CSNK1E -10595
PSMB7 -10578
POM121C -10473
TUBA3D -10346
DCTN2 -10239
YWHAG -10207
TUBB4B -10078
TUBG2 -10039
H4C3 -9942
LBR -9832
CSNK2A1 -9812
SMC2 -9640
CEP41 -9604
H2BC12 -9581
UBC -9558
PSMD5 -9539
H4C11 -9492
DYNLL1 -9489

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
H3C6 -10650.0
CSNK1E -10595.0
PSMB7 -10578.0
POM121C -10473.0
TUBA3D -10346.0
DCTN2 -10239.0
YWHAG -10207.0
TUBB4B -10078.0
TUBG2 -10039.0
H4C3 -9942.0
LBR -9832.0
CSNK2A1 -9812.0
SMC2 -9640.0
CEP41 -9604.0
H2BC12 -9581.0
UBC -9558.0
PSMD5 -9539.0
H4C11 -9492.0
DYNLL1 -9489.0
H4C9 -9486.0
DYNC1LI1 -9445.0
H2BC5 -9371.0
NEK9 -9304.0
H3-3A -9260.0
H4C16 -9179.0
RAB2A -9166.0
H2AC4 -9092.0
UBE2E1 -9071.0
KMT5A -9054.0
RAE1 -9026.0
CLIP1 -8978.0
CSNK2A2 -8850.0
CNEP1R1 -8817.0
TUBB4A -8809.0
CENPA -8800.0
RB1 -8767.0
PDS5A -8763.0
CHMP4A -8725.0
MAPK1 -8617.0
CDC16 -8598.0
NEK7 -8538.0
H2BC1 -8504.0
PPP2R5B -8503.0
HAUS2 -8502.0
NME7 -8404.0
H4C13 -8401.0
H3-3B -8363.0
PCM1 -8345.0
NSL1 -8302.0
CNTRL -8294.0
H3C8 -8260.0
H2BC3 -8237.0
CENPQ -8231.0
MZT2A -8124.0
H2BC8 -8108.0
PSME1 -8101.0
PSMA6 -7988.0
NDE1 -7893.0
NUP50 -7820.0
NEDD1 -7817.0
KIF2C -7797.0
ZWINT -7770.0
CCNB2 -7768.0
NUDC -7747.0
H3C11 -7686.0
CEP72 -7656.0
NUP93 -7632.0
CEP43 -7565.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
H2AJ -7338.0
ENSA -7326.0
CHMP2B -7324.0
PTTG1 -7296.0
ZWILCH -7287.0
GORASP1 -7243.0
ODF2 -7132.0
CEP78 -7050.0
CEP70 -7040.0
H2BC10 -6977.0
BUB1B -6938.0
H3C3 -6933.0
TUBAL3 -6859.0
TUBA4A -6826.0
H3C12 -6825.0
BLZF1 -6782.0
H2AC8 -6733.0
VRK2 -6642.0
CDK5RAP2 -6558.0
DYNC1I2 -6523.0
H2AC18 -6516.5
H2AC19 -6516.5
TUBB3 -6481.0
TUBA4B -6407.0
PSMD13 -6393.0
CLASP2 -6389.0
PPP2R2A -6359.0
SPC24 -6225.0
TUBGCP3 -6224.0
PSMC6 -6219.0
MCPH1 -6206.0
KIF2B -6144.0
AKAP9 -6138.0
SEC13 -6136.0
PSME2 -6132.0
H2BC14 -6126.0
NEK2 -6109.0
CDC26 -6099.0
ANAPC10 -6095.0
ACTR1A -6083.0
TUBA1A -6069.0
SDCCAG8 -6001.0
SMC4 -5947.0
NUP155 -5935.0
ANAPC7 -5877.0
PAFAH1B1 -5709.0
ITGB3BP -5665.0
TNPO1 -5632.0
PLK4 -5568.0
RAB1A -5565.0
H3C2 -5478.0
HAUS3 -5461.0
TUBB2A -5397.0
HAUS4 -5369.0
SKA1 -5357.0
H2AC7 -5340.5
H2BC7 -5340.5
NUP153 -5310.0
POM121 -5300.0
TAOK1 -5276.0
NCAPD2 -5155.0
CHMP6 -5085.0
RAB1B -5084.0
NDC80 -5070.0
CCP110 -4990.0
SGO2 -4989.0
CENPC -4957.0
LPIN2 -4698.0
KNL1 -4647.0
PSMB10 -4606.0
TUBB6 -4561.0
XPO1 -4530.0
CEP76 -4407.0
PSMB2 -4344.0
DYNC1H1 -4301.0
CENPP -4279.0
PPP2R2D -4227.0
NCAPG2 -4222.0
CDC23 -4153.0
NUP188 -4141.0
RCC2 -4121.0
CEP63 -4104.0
RCC1 -4097.0
CENPT -4073.0
PSMD7 -4057.0
TMPO -4027.0
CDC27 -4025.0
H4C4 -4007.0
TUBGCP2 -4000.0
NUP133 -3990.0
NDEL1 -3912.0
CENPO -3864.0
CHMP2A -3860.0
CKAP5 -3856.0
MAU2 -3832.0
GOLGA2 -3802.0
H2BC21 -3732.0
PPP2R5E -3635.0
H4C6 -3568.0
HAUS1 -3554.0
SFI1 -3534.0
KIF18A -3490.0
RPS27 -3484.0
PSMA7 -3416.0
H2AC14 -3377.0
PSME3 -3245.0
ESPL1 -3216.0
NCAPG -3211.0
PRKCB -3201.0
TUBA1C -3186.0
NUP42 -3160.0
DSN1 -3120.0
STAG1 -3119.0
H3C4 -3045.0
AURKB -2861.0
HAUS8 -2836.0
PSMC4 -2787.0
CDK1 -2730.0
FBXO5 -2720.0
SGO1 -2709.0
NUP98 -2703.0
CENPL -2691.0
PMF1 -2655.0
USO1 -2632.0
CLASP1 -2556.0
TUBA8 -2524.0
NUP160 -2508.0
INCENP -2499.0
PPP2CB -2471.0
CEP131 -2380.0
HSP90AA1 -2213.0
CSNK2B -2185.0
SEM1 -2183.0
CHMP4C -2173.0
SPC25 -2166.0
DYNC1I1 -2149.0
CENPE -2121.0
AHCTF1 -2112.0
TUBB2B -2109.0
PDS5B -2101.0
SUMO1 -2089.0
ANAPC5 -2079.0
NUP35 -2059.0
DCTN1 -2023.0
CHMP3 -2000.0
PSMB6 -1996.0
PSMD14 -1965.0
B9D2 -1934.0
NUMA1 -1745.0
RAD21 -1610.0
KIF23 -1597.0
CSNK1D -1577.0
PLK1 -1530.0
LMNB1 -1456.0
PSMD9 -1453.0
PSMC5 -1352.0
SMC3 -1334.0
PPP2R5D -1303.0
PSMB4 -1200.0
H3C10 -1128.0
H4C12 -1092.0
SSNA1 -1082.0
ALMS1 -1048.0
KIF20A -1025.0
PSMA3 -989.0
TUBB -950.0
PRKACA -933.0
AAAS -910.0
H4C2 -859.0
PSMC2 -840.0
NUP37 -825.0
CENPN -774.0
UBE2C -706.0
PSMD6 -684.0
CENPM -681.0
RANGAP1 -663.0
SET -625.0
MIS12 -582.0
PCNT -547.0
NUP43 -528.0
PSMD11 -524.0
ANAPC15 -493.0
NUP214 -489.0
PSMB1 -483.0
CEP57 -401.0
PSMA4 -398.0
TUBA3C -374.0
TUBGCP5 -373.0
MAD1L1 -288.0
VRK1 -268.0
MASTL -179.0
TUBA3E -95.0
TUBG1 -30.0
H2BC13 1.0
BUB1 3.0
UBE2S 7.0
CDCA5 37.0
PSMD4 55.0
ANKLE2 78.0
CEP290 127.0
NUP85 327.0
PSMD12 373.0
PPP2R5C 395.0
PPP1CC 455.0
CENPH 476.0
KPNB1 488.0
CEP152 501.0
PSMF1 550.0
GORASP2 630.0
IST1 734.0
PSMA2 776.0
UBE2I 794.0
BUB3 813.0
H3-4 835.0
ANAPC11 853.0
SIRT2 1014.0
WAPL 1021.0
NUP54 1027.0
EML4 1046.0
YWHAE 1068.0
PSMD3 1087.0
PSMB9 1093.0
ANAPC4 1161.0
SPAST 1221.0
RANBP2 1258.0
UBB 1320.0
NUF2 1321.0
TUBGCP6 1346.0
MAPRE1 1433.0
H4C8 1444.0
H2BC26 1619.0
NUP88 1774.0
RAN 1799.0
LEMD3 1803.0
PSMA5 1847.0
CHMP7 1896.0
PPP2R5A 1963.0
CEP192 1984.0
PSMB8 2004.0
NCAPH 2016.0
PPP2R1B 2037.0
NUP210 2136.0
PSMA1 2177.0
ANAPC16 2196.0
H2BC15 2203.0
RPS27A 2313.0
NUP107 2333.0
SKA2 2357.0
H2BC4 2363.0
LMNA 2364.0
CENPJ 2408.0
NDC1 2461.0
LPIN1 2580.0
H4C1 2583.0
PPP2CA 2625.0
DYNC1LI2 2640.0
UBA52 2643.0
PSMD8 2754.0
MZT2B 2863.0
VPS4A 2877.0
CENPS 2903.0
CDC20 2914.0
NCAPD3 2979.0
PRKCA 3022.0
PSME4 3100.0
PSMD1 3155.0
H2AC20 3179.0
CEP164 3190.0
CCNB1 3317.0
HAUS6 3637.0
TUBGCP4 3739.0
CENPU 3842.0
KIF2A 3843.0
SPDL1 3844.0
KNTC1 3867.0
ARPP19 3901.0
CENPF 4067.0
H2BC17 4130.0
CC2D1B 4231.0
NIPBL 4313.0
ANAPC1 4318.0
NUP58 4456.0
ANAPC2 4548.0
PRKAR2B 4569.0
BANF1 4582.0
H2BC11 4657.0
TUBA1B 4671.0
NEK6 4718.0
H3C1 4735.0
PSMC1 4758.0
PSMB3 5015.0
HAUS5 5396.0
H4C5 5401.0
H2AZ2 5485.0
TUBB1 5561.0
CEP250 5608.0
PSMC3 5724.0
PSMB5 5798.0
MZT1 5950.0
CHMP4B 5954.0
CEP135 6155.0
ZW10 6165.0
PPP2R1A 6221.0
H2AC6 6426.0
CTDNEP1 6564.0
H2AX 6737.0
NUP205 6912.0
UBE2D1 7063.0
TPR 7154.0
MAD2L1 7226.0
CDCA8 7291.0
CENPK 7336.0
BIRC5 7359.0
NUP62 7697.0
LEMD2 7754.0
DCTN3 7804.0
MAPK3 7947.0
NCAPH2 7983.0
PSMD2 8298.0
SEH1L 8440.0
LPIN3 8445.0
PSMA8 8939.0
DYNLL2 9125.0
NINL 9408.0
PSMB11 10222.0
TUBB8 10871.0



REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS

REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS
1476
set REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS
setSize 83
pANOVA 2.89e-11
s.dist -0.422
p.adjustANOVA 3.64e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
CEBPE -10834
SPI1 -10725
H2BC6 -10708
H3C6 -10650
GATA2 -10464
CEBPA -10388
MYB -10255
RARA -9950
H4C3 -9942
EP300 -9776
IL6R -9670
H2BC12 -9581
TAL1 -9534
H4C11 -9492
H4C9 -9486
RUNX1 -9414
H2BC5 -9371
H3-3A -9260
H4C16 -9179
H2AC4 -9092

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CEBPE -10834.0
SPI1 -10725.0
H2BC6 -10708.0
H3C6 -10650.0
GATA2 -10464.0
CEBPA -10388.0
MYB -10255.0
RARA -9950.0
H4C3 -9942.0
EP300 -9776.0
IL6R -9670.0
H2BC12 -9581.0
TAL1 -9534.0
H4C11 -9492.0
H4C9 -9486.0
RUNX1 -9414.0
H2BC5 -9371.0
H3-3A -9260.0
H4C16 -9179.0
H2AC4 -9092.0
TFDP2 -8530.0
H2BC1 -8504.0
H4C13 -8401.0
H3-3B -8363.0
H3C8 -8260.0
H2BC3 -8237.0
TFDP1 -8155.0
H2BC8 -8108.0
CDK2 -8046.0
H3C11 -7686.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
H2AJ -7338.0
H2BC10 -6977.0
H3C3 -6933.0
CBFB -6875.0
CEBPB -6830.0
H3C12 -6825.0
PML -6800.0
FLI1 -6788.0
H2AC8 -6733.0
RXRA -6640.0
H2AC18 -6516.5
H2AC19 -6516.5
H2BC14 -6126.0
H3C2 -5478.0
H2AC7 -5340.5
H2BC7 -5340.5
CDK4 -5202.0
CDKN1A -5005.0
STAT3 -4580.0
GFI1 -4517.0
H4C4 -4007.0
H2BC21 -3732.0
KLF5 -3616.0
H4C6 -3568.0
H2AC14 -3377.0
H3C4 -3045.0
MYC -2072.0
KMT2A -1135.0
H3C10 -1128.0
H4C12 -1092.0
DEK -1023.0
H4C2 -859.0
H2BC13 1.0
H4C8 1444.0
H2BC26 1619.0
H2BC15 2203.0
CREB1 2212.0
H2BC4 2363.0
H4C1 2583.0
H2AC20 3179.0
H2BC17 4130.0
H2BC11 4657.0
H3C1 4735.0
CSF3R 5041.0
LEF1 5275.0
H4C5 5401.0
H2AZ2 5485.0
H2AC6 6426.0
H2AX 6737.0
E2F1 7131.0



REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE

REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE
501
set REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE
setSize 118
pANOVA 5.57e-11
s.dist -0.349
p.adjustANOVA 6.53e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
MIR24-2 -10899
H2BC6 -10708
H3C6 -10650
AGO4 -9949
H4C3 -9942
H2BC12 -9581
UBC -9558
MAPKAPK3 -9529
H4C11 -9492
H4C9 -9486
H2BC5 -9371
BMI1 -9287
H3-3A -9260
H4C16 -9179
MIR24-1 -9163
CBX6 -9157
TXN -9118
H2AC4 -9092
E2F2 -8947
CBX8 -8780

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MIR24-2 -10899.0
H2BC6 -10708.0
H3C6 -10650.0
AGO4 -9949.0
H4C3 -9942.0
H2BC12 -9581.0
UBC -9558.0
MAPKAPK3 -9529.0
H4C11 -9492.0
H4C9 -9486.0
H2BC5 -9371.0
BMI1 -9287.0
H3-3A -9260.0
H4C16 -9179.0
MIR24-1 -9163.0
CBX6 -9157.0
TXN -9118.0
H2AC4 -9092.0
E2F2 -8947.0
CBX8 -8780.0
MAPK1 -8617.0
MAP3K5 -8582.0
TFDP2 -8530.0
H2BC1 -8504.0
MAP2K6 -8430.0
H4C13 -8401.0
H3-3B -8363.0
PHC3 -8272.0
H3C8 -8260.0
H2BC3 -8237.0
TFDP1 -8155.0
H2BC8 -8108.0
CDK6 -8085.0
PHC1 -7771.0
CDKN2A -7757.0
MAPKAPK2 -7751.0
CDKN2B -7709.0
H3C11 -7686.0
AGO3 -7679.0
EZH2 -7675.0
CDKN2C -7581.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
TNRC6B -7491.0
H2AJ -7338.0
MINK1 -7041.0
EED -7009.0
H2BC10 -6977.0
H3C3 -6933.0
H3C12 -6825.0
H2AC8 -6733.0
H2AC18 -6516.5
H2AC19 -6516.5
MAPKAPK5 -6287.0
H2BC14 -6126.0
AGO1 -6050.0
RNF2 -5882.0
H3C2 -5478.0
CBX2 -5379.0
H2AC7 -5340.5
H2BC7 -5340.5
CDK4 -5202.0
MOV10 -4504.0
E2F3 -4451.0
TNRC6C -4438.0
MAPK14 -4437.0
MAPK9 -4226.0
MAP2K7 -4122.0
H4C4 -4007.0
TNIK -3843.0
H2BC21 -3732.0
H4C6 -3568.0
H2AC14 -3377.0
KDM6B -3253.0
H3C4 -3045.0
MAP2K4 -2820.0
MAP2K3 -1752.0
PHC2 -1440.0
H3C10 -1128.0
H4C12 -1092.0
MDM2 -1085.0
RING1 -863.0
H4C2 -859.0
TP53 -831.0
MDM4 -86.0
RBBP4 -33.0
SCMH1 -17.0
H2BC13 1.0
FOS 612.0
UBB 1320.0
H4C8 1444.0
H2BC26 1619.0
TNRC6A 1957.0
H2BC15 2203.0
RPS27A 2313.0
H2BC4 2363.0
H4C1 2583.0
UBA52 2643.0
IFNB1 2718.0
CBX4 2785.0
MAPK10 2866.0
JUN 3045.0
H2AC20 3179.0
MAP4K4 3287.0
MAPK8 3520.0
H2BC17 4130.0
H2BC11 4657.0
H3C1 4735.0
H4C5 5401.0
H2AZ2 5485.0
SUZ12 5843.0
H2AC6 6426.0
H2AX 6737.0
E2F1 7131.0
MAPK3 7947.0
CDKN2D 8586.0
MAPK11 8999.0



REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1
1272
set REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1
setSize 229
pANOVA 2.63e-10
s.dist -0.242
p.adjustANOVA 2.88e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
NFE2 -10939
MIR27A -10861
SPI1 -10725
H2BC6 -10708
H3C6 -10650
PSMB7 -10578
GATA2 -10464
IL3 -10437
MYB -10255
GP1BA -10230
SOCS3 -10048
AGO4 -9949
H4C3 -9942
LMO2 -9851
CSNK2A1 -9812
YAF2 -9795
EP300 -9776
NFATC2 -9680
H2BC12 -9581
UBC -9558

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NFE2 -10939.0
MIR27A -10861.0
SPI1 -10725.0
H2BC6 -10708.0
H3C6 -10650.0
PSMB7 -10578.0
GATA2 -10464.0
IL3 -10437.0
MYB -10255.0
GP1BA -10230.0
SOCS3 -10048.0
AGO4 -9949.0
H4C3 -9942.0
LMO2 -9851.0
CSNK2A1 -9812.0
YAF2 -9795.0
EP300 -9776.0
NFATC2 -9680.0
H2BC12 -9581.0
UBC -9558.0
PSMD5 -9539.0
TAL1 -9534.0
H4C11 -9492.0
H4C9 -9486.0
RUNX1 -9414.0
RBBP5 -9393.0
RYBP -9384.0
H2BC5 -9371.0
BMI1 -9287.0
H3-3A -9260.0
SMARCC2 -9250.0
PCGF5 -9194.0
H4C16 -9179.0
CBX6 -9157.0
H2AC4 -9092.0
GATA3 -9064.0
CSF2 -8999.0
CSNK2A2 -8850.0
CBX8 -8780.0
RUNX2 -8699.0
H2BC1 -8504.0
KAT2B -8472.0
LDB1 -8418.0
H4C13 -8401.0
H3-3B -8363.0
AXIN1 -8331.0
PHC3 -8272.0
H3C8 -8260.0
H2BC3 -8237.0
SMARCA2 -8188.0
H2BC8 -8108.0
PSME1 -8101.0
CDK6 -8085.0
PSMA6 -7988.0
PHC1 -7771.0
CLDN5 -7705.0
H3C11 -7686.0
PRMT1 -7681.0
AGO3 -7679.0
TNFRSF18 -7578.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
TNRC6B -7491.0
H2AJ -7338.0
TCF12 -7186.0
CR1 -7165.0
PBRM1 -7061.0
NR4A3 -6991.0
H2BC10 -6977.0
H3C3 -6933.0
CBFB -6875.0
ASH2L -6843.0
H3C12 -6825.0
PML -6800.0
H2AC8 -6733.0
PRKCQ -6522.0
H2AC18 -6516.5
H2AC19 -6516.5
ARID2 -6420.0
PSMD13 -6393.0
CCND2 -6290.0
PSMC6 -6219.0
PSME2 -6132.0
H2BC14 -6126.0
CCNH -6119.0
AGO1 -6050.0
CCND3 -5993.0
KMT2D -5933.0
RNF2 -5882.0
H3C2 -5478.0
CBX2 -5379.0
H2AC7 -5340.5
H2BC7 -5340.5
SMARCE1 -4940.0
SMARCD1 -4900.0
CTSL -4854.0
GPAM -4680.0
IL2RA -4619.0
PSMB10 -4606.0
MOV10 -4504.0
TNRC6C -4438.0
ELF1 -4376.0
PSMB2 -4344.0
ZFPM1 -4194.0
PSMD7 -4057.0
H4C4 -4007.0
TJP1 -3989.0
ARID1B -3929.0
DPY30 -3892.0
H2BC21 -3732.0
H4C6 -3568.0
PSMA7 -3416.0
H2AC14 -3377.0
PSME3 -3245.0
MNAT1 -3244.0
ITCH -3210.0
PRKCB -3201.0
H3C4 -3045.0
KMT2E -2890.0
PSMC4 -2787.0
SMARCD2 -2528.0
PTPN11 -2297.0
CSNK2B -2185.0
SEM1 -2183.0
SETD1A -2122.0
PSMB6 -1996.0
PSMD14 -1965.0
HIPK2 -1566.0
PSMD9 -1453.0
PHC2 -1440.0
SIN3A -1392.0
PSMC5 -1352.0
PSMB4 -1200.0
KMT2A -1135.0
H3C10 -1128.0
H4C12 -1092.0
PSMA3 -989.0
RSPO3 -947.0
RING1 -863.0
H4C2 -859.0
PSMC2 -840.0
PSMD6 -684.0
ABL1 -558.0
PSMD11 -524.0
PSMB1 -483.0
PSMA4 -398.0
OCLN -230.0
ARID1A -221.0
SCMH1 -17.0
H2BC13 1.0
PSMD4 55.0
TCF3 67.0
WDR5 156.0
ACTL6A 268.0
PSMD12 373.0
ACTL6B 524.0
PSMF1 550.0
PSMA2 776.0
LGALS3 781.0
SOCS4 829.0
KMT2C 917.0
PSMD3 1087.0
PSMB9 1093.0
CCND1 1122.0
LMO1 1210.0
UBB 1320.0
H4C8 1444.0
SETD1B 1496.0
H2BC26 1619.0
PSMA5 1847.0
CDK7 1850.0
ITGA2B 1860.0
TNRC6A 1957.0
PSMB8 2004.0
AGO2 2114.0
PSMA1 2177.0
H2BC15 2203.0
AUTS2 2227.0
RPS27A 2313.0
KCTD6 2338.0
H2BC4 2363.0
ELF2 2413.0
H4C1 2583.0
UBA52 2643.0
PSMD8 2754.0
CBX4 2785.0
PSME4 3100.0
PSMD1 3155.0
H2AC20 3179.0
SIN3B 3728.0
PRMT6 3920.0
YAP1 4098.0
H2BC17 4130.0
SMARCA4 4350.0
IL2 4413.0
TP73 4436.0
H2BC11 4657.0
H3C1 4735.0
PSMC1 4758.0
ESR1 4769.0
HDAC1 4949.0
PSMB3 5015.0
SERPINB13 5042.0
LIFR 5220.0
SMARCD3 5277.0
H4C5 5401.0
H2AZ2 5485.0
SRC 5689.0
PSMC3 5724.0
CREBBP 5734.0
PSMB5 5798.0
THBS1 5846.0
CTSV 6149.0
H2AC6 6426.0
H2AX 6737.0
CTSK 6865.0
SMARCC1 7024.0
PAX5 7252.0
IFNG 7597.0
BLK 7915.0
PSMD2 8298.0
PF4 8611.0
PSMA8 8939.0
MYL9 9962.0
KMT2B 10017.0
SMARCB1 10098.0
PSMB11 10222.0
CTLA4 10548.0



REACTOME_INFECTIOUS_DISEASE

REACTOME_INFECTIOUS_DISEASE
974
set REACTOME_INFECTIOUS_DISEASE
setSize 910
pANOVA 2.83e-10
s.dist -0.123
p.adjustANOVA 2.91e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
FGR -10813
STING1 -10809
IFNA2 -10803
CTSG -10796
H2BC6 -10708
MOGS -10704
GNAS -10665
H3C6 -10650
ENO1 -10645
IL1B -10628
NOD1 -10608
PSMB7 -10578
IL10 -10556
C3AR1 -10553
CALR -10512
NLRP3 -10484
POM121C -10473
PRKACG -10472
POLR2C -10372
TUBA3D -10346

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FGR -10813.0
STING1 -10809.0
IFNA2 -10803.0
CTSG -10796.0
H2BC6 -10708.0
MOGS -10704.0
GNAS -10665.0
H3C6 -10650.0
ENO1 -10645.0
IL1B -10628.0
NOD1 -10608.0
PSMB7 -10578.0
IL10 -10556.0
C3AR1 -10553.0
CALR -10512.0
NLRP3 -10484.0
POM121C -10473.0
PRKACG -10472.0
POLR2C -10372.0
TUBA3D -10346.0
FXYD7 -10283.0
PYCARD -10282.0
BST2 -10269.0
BRD4 -10262.0
ERCC3 -10242.0
PPIB -10233.0
YWHAG -10207.0
CDC42 -10147.0
IL6 -10121.0
TUBB4B -10078.0
IFNGR2 -10049.0
GNB5 -10046.0
NOD2 -10042.0
VPS18 -10027.0
H4C3 -9942.0
ITPR1 -9913.0
MAP2K1 -9899.0
AHCYL1 -9882.0
NFE2L2 -9875.0
FCGR3A -9874.0
TLR1 -9777.0
EP300 -9776.0
JAK3 -9772.0
CNBP -9771.0
PARP4 -9722.0
ST3GAL2 -9716.0
RPN1 -9708.0
RPL29 -9703.0
IL6R -9670.0
SFTPD -9655.0
H2BC12 -9581.0
UBC -9558.0
VPS16 -9540.0
PSMD5 -9539.0
TRIM4 -9532.0
PIK3C3 -9526.0
RAC1 -9520.0
CYSLTR2 -9495.0
H4C11 -9492.0
DYNLL1 -9489.0
H4C9 -9486.0
WASL -9476.0
DYNC1LI1 -9445.0
RUNX1 -9414.0
RPLP1 -9411.0
H2BC5 -9371.0
H2AC16 -9348.0
DNAJC3 -9320.0
RCOR1 -9289.0
NCKAP1L -9254.0
TRAF6 -9223.0
YES1 -9222.0
RPS23 -9195.0
H4C16 -9179.0
MAP2K2 -9169.0
VAV1 -9126.0
TXN -9118.0
H2AC4 -9092.0
CANX -9039.0
MEFV -9034.0
RAE1 -9026.0
ARF1 -8984.0
CASP1 -8859.0
ADORA2B -8837.0
SEC24A -8812.0
TUBB4A -8809.0
RB1 -8767.0
IFNAR1 -8760.0
GATAD2B -8745.0
SRPK1 -8728.0
CHMP4A -8725.0
RPS29 -8722.0
TBK1 -8689.0
ISG15 -8683.0
IL18 -8664.0
MAPK1 -8617.0
EDEM2 -8585.0
PABPN1 -8563.0
H2BC1 -8504.0
PSIP1 -8496.0
TXNIP -8480.0
NCOR2 -8471.0
FNTB -8461.0
MAP2K6 -8430.0
GJA1 -8427.0
IL17RC -8422.0
PPIH -8416.0
H4C13 -8401.0
CALM1 -8399.0
KPNA1 -8349.0
WASF2 -8328.0
TAB2 -8307.0
GTF2A2 -8284.0
CXCR4 -8271.0
H3C8 -8260.0
H2BC3 -8237.0
VPS37C -8205.0
G3BP1 -8200.0
GEMIN7 -8160.0
H2BC8 -8108.0
PSME1 -8101.0
STT3A -8094.0
RPL11 -8055.0
TAF12 -8042.0
FXYD1 -7995.0
PSMA6 -7988.0
PRKACB -7972.0
SUPT4H1 -7958.0
RHBDF2 -7952.0
SNRPB -7928.0
AP1S1 -7907.0
ZDHHC3 -7891.0
STAM -7881.0
NUP50 -7820.0
RBX1 -7781.0
IRF3 -7758.0
RIPK3 -7739.0
HSP90AB1 -7735.0
EPS15 -7704.0
POLR2K -7697.0
IFNAR2 -7694.0
H3C11 -7686.0
PRMT1 -7681.0
EZH2 -7675.0
SAP18 -7662.0
CRBN -7649.0
NUP93 -7632.0
H2BC9 -7522.5
H3C7 -7522.5
RPL22 -7474.0
CTNND1 -7472.0
IMPDH1 -7445.0
GNB2 -7436.0
CBL -7394.0
HSPA1A -7384.0
H2AC21 -7374.0
WIPF1 -7342.0
CHMP2B -7324.0
HLA-A -7308.0
NMI -7275.0
SAR1B -7270.0
POLR2A -7267.0
CDK9 -7238.0
RIPK2 -7234.0
SAP30 -7138.0
KPNA3 -7094.0
CUL3 -7084.0
GALNT1 -7079.0
STX1A -7045.0
MGAT4A -7026.0
MGAT4B -7011.0
EED -7009.0
FAU -6993.0
H2BC10 -6977.0
TYK2 -6957.0
ZCRB1 -6939.0
H3C3 -6933.0
SEC24D -6903.0
MAP1LC3B -6900.0
ANTXR2 -6896.0
RPL27 -6893.0
TSG101 -6877.0
TUBAL3 -6859.0
TUBA4A -6826.0
H3C12 -6825.0
BRK1 -6818.0
PML -6800.0
RPL23 -6779.0
AP1M2 -6763.0
RPL21 -6753.0
H2AC8 -6733.0
GNG3 -6698.0
ELMO1 -6692.0
CUL5 -6662.0
GTF2B -6622.0
GNGT1 -6589.0
RPS9 -6580.0
RPL34 -6560.0
TAF15 -6543.0
GTF2F1 -6537.0
DYNC1I2 -6523.0
H2AC18 -6516.5
H2AC19 -6516.5
GNG10 -6483.0
TUBB3 -6481.0
HBEGF -6448.0
IL17RA -6440.0
TUBA4B -6407.0
PSMD13 -6393.0
RPL10A -6330.0
YWHAH -6318.0
GNAI3 -6294.0
FCGR2A -6280.0
H2AC1 -6275.0
GEMIN2 -6263.0
MYO9B -6250.0
MAN2A1 -6229.0
PSMC6 -6219.0
ST3GAL4 -6174.0
YWHAZ -6164.0
VPS36 -6155.0
SEC13 -6136.0
PSME2 -6132.0
H2BC14 -6126.0
CCNH -6119.0
VPS33B -6097.0
XRCC4 -6070.0
TUBA1A -6069.0
MYH2 -6047.0
HNRNPA1 -6029.0
GEMIN4 -6013.0
SP1 -5960.0
NUP155 -5935.0
SEC23A -5922.0
SMN1 -5909.5
SMN2 -5909.5
MBD3 -5903.0
FXYD2 -5895.0
SUDS3 -5886.0
PTGES3 -5864.0
IKBKB -5839.0
ROCK2 -5794.0
DDX20 -5707.0
ENTPD1 -5695.0
ZBP1 -5676.0
ACTR2 -5655.0
LIG1 -5649.0
P2RX7 -5641.0
GSK3B -5572.0
HDAC2 -5534.0
CLTA -5506.0
RPS20 -5483.0
H3C2 -5478.0
APP -5475.0
RNGTT -5471.0
MAP3K7 -5435.0
TUBB2A -5397.0
ROCK1 -5392.0
GTF2E1 -5387.0
ADCY4 -5351.0
H2AC7 -5340.5
H2BC7 -5340.5
DPEP3 -5329.0
ARID4A -5327.0
NUP153 -5310.0
POM121 -5300.0
TRIM28 -5298.0
GNG11 -5292.0
ITPR2 -5260.0
VPS28 -5222.0
H2AC12 -5204.0
TAF4B -5149.0
RAB7A -5134.0
NMT1 -5117.0
SSRP1 -5110.0
AP2M1 -5107.0
CHMP6 -5085.0
VEGFA -5078.0
IFNA21 -5061.0
ACTG1 -5045.0
ANO10 -5003.0
LIG4 -4996.0
RPS26 -4941.0
ATG14 -4907.0
ATP1B3 -4897.0
HCK -4883.0
SNRPD3 -4881.0
CTSL -4854.0
NFKBIA -4831.0
PSTPIP1 -4810.0
JAK1 -4805.0
ELOC -4748.0
RPL9 -4728.0
PATJ -4725.0
KPNA7 -4724.0
VPS37A -4694.0
UVRAG -4685.0
VCP -4679.0
CCR5 -4659.0
DUSP16 -4643.0
PSMB10 -4606.0
PDCD6IP -4582.0
RPL18 -4575.0
TUBB6 -4561.0
XPO1 -4530.0
NELFB -4457.0
MAPK14 -4437.0
VAMP1 -4410.0
IFIH1 -4395.0
AKT1 -4393.0
GTF2H5 -4378.0
TAF7 -4369.0
PSMB2 -4344.0
APOBEC3G -4337.0
VPS4B -4332.0
TXNRD1 -4302.0
DYNC1H1 -4301.0
ST3GAL1 -4277.0
GTF2A1 -4237.0
TBP -4230.0
VPS33A -4218.0
ADAM17 -4207.0
GRB2 -4184.0
RIPK1 -4183.0
RPN2 -4174.0
PLK2 -4154.0
PHF21A -4143.0
NUP188 -4141.0
ELL -4130.0
MAP2K7 -4122.0
LYN -4113.0
RCC1 -4097.0
CTDP1 -4083.0
AP2B1 -4081.0
PSMD7 -4057.0
ZDHHC2 -4053.0
TBL1XR1 -4015.0
H4C4 -4007.0
NUP133 -3990.0
TJP1 -3989.0
TUFM -3988.0
ITGB1 -3970.0
RPL15 -3918.0
CHUK -3913.0
GSK3A -3880.0
PARP14 -3865.0
CHMP2A -3860.0
HMGA1 -3826.0
GNG7 -3819.0
SH3GL2 -3804.0
AP2A1 -3781.0
TOMM70 -3759.0
H2BC21 -3732.0
JAK2 -3714.0
GUCY2C -3702.0
RELA -3661.0
GTF2H1 -3642.0
SRPK2 -3630.0
RPL26 -3628.0
MVB12A -3624.0
AKT3 -3595.0
SEC24C -3587.0
RPL10L -3574.0
H4C6 -3568.0
ARPC3 -3530.0
GNAI2 -3527.0
GNB1 -3520.0
VTA1 -3517.0
RPS27 -3484.0
PPIG -3461.0
UBE2N -3431.0
PSMA7 -3416.0
NR3C1 -3398.0
H2AC14 -3377.0
LTF -3357.0
PPIA -3347.0
RPL30 -3326.0
PSME3 -3245.0
MNAT1 -3244.0
BECN1 -3236.0
SKP1 -3229.0
GEMIN6 -3213.0
ZDHHC20 -3212.0
ITCH -3210.0
ABI2 -3209.0
PRKAR1A -3197.0
TAF2 -3194.0
TUBA1C -3186.0
NUP42 -3160.0
VAMP2 -3158.0
TAF9 -3142.0
UBAP1 -3098.0
AP1M1 -3083.0
ANO6 -3062.0
H3C4 -3045.0
MTA2 -2984.0
CSNK1A1 -2960.0
NCK1 -2917.0
CLTC -2915.0
ARPC1B -2913.0
POLR2I -2893.0
LARP1 -2863.0
MAP2K4 -2820.0
VPS39 -2809.0
PSMC4 -2787.0
COMT -2733.0
SUPT16H -2715.0
NUP98 -2703.0
AP1B1 -2672.0
GPS2 -2644.0
SNRPF -2638.0
SDC3 -2624.0
NCKAP1 -2620.0
GNB4 -2618.0
POLR2B -2615.0
GTF2H3 -2584.0
RPL4 -2541.0
PIK3R4 -2533.0
TUBA8 -2524.0
NUP160 -2508.0
CD79A -2501.0
ST6GALNAC4 -2442.0
TRIM27 -2433.0
RPS6 -2406.0
GATAD2A -2405.0
GEMIN5 -2399.0
MGAT1 -2370.0
TGFB1 -2362.0
GNG12 -2359.0
ATP6V1H -2333.0
DPEP2 -2323.0
PTPN11 -2297.0
ARPC5 -2287.0
ACTR3 -2275.0
GGT1 -2237.0
HSP90AA1 -2213.0
ELOA2 -2193.0
SEM1 -2183.0
ADCY7 -2182.0
GNG5 -2179.0
CHMP4C -2173.0
DYNC1I1 -2149.0
CBLL1 -2119.0
TUBB2B -2109.0
SUMO1 -2089.0
BRMS1 -2063.0
NUP35 -2059.0
CHMP3 -2000.0
PSMB6 -1996.0
VAV3 -1981.0
PSMD14 -1965.0
FURIN -1963.0
ITGA4 -1906.0
SMAD4 -1810.0
DVL1 -1797.0
MAP2K3 -1752.0
RPL24 -1718.0
PALS1 -1633.0
MAN1B1 -1523.0
RPS25 -1469.0
IL1R1 -1468.0
PSMD9 -1453.0
RPL5 -1417.0
NCBP2 -1379.0
RPL18A -1362.0
RPS19 -1355.0
PSMC5 -1352.0
RPL13 -1344.0
SIKE1 -1330.0
TRIM25 -1291.0
POLR2G -1251.0
GSDMD -1236.0
PSMB4 -1200.0
MTA1 -1189.0
H3C10 -1128.0
H4C12 -1092.0
VPS45 -1021.0
PCBP2 -993.0
PSMA3 -989.0
KDM1A -970.0
ATP1A1 -952.0
TUBB -950.0
ANO5 -942.0
PRKACA -933.0
AAAS -910.0
H4C2 -859.0
FYN -844.0
PSMC2 -840.0
NUP37 -825.0
RPL27A -824.0
SIGMAR1 -799.0
TAF3 -770.0
KPNA4 -768.0
PLCG2 -757.0
RPS15A -688.0
PSMD6 -684.0
CEBPD -678.0
REST -668.0
RANGAP1 -663.0
RPL37A -652.0
XRCC5 -615.0
RPS27L -610.0
ABL1 -558.0
NUP43 -528.0
PSMD11 -524.0
KPNA5 -497.0
NUP214 -489.0
PSMB1 -483.0
ACTB -471.0
IFNGR1 -470.0
SV2C -468.0
PSMA4 -398.0
VPS11 -392.0
TUBA3C -374.0
NCBP1 -338.0
RPL35 -307.0
RPL28 -294.0
NFKB1 -285.0
EIF2AK2 -244.0
RPS8 -175.0
ZDHHC5 -151.0
GNG8 -148.0
H2AC17 -112.0
TUBA3E -95.0
SNAP25 -90.0
RPL35A -84.0
SEC24B -71.0
RBBP4 -33.0
IPO5 -32.0
SNF8 -25.0
YWHAQ -11.0
H2BC13 1.0
AP1S3 26.0
HMG20B 51.0
ANO3 53.0
PSMD4 55.0
PAK2 116.0
WNT5A 130.0
MGAT5 132.0
CYBA 145.0
H2AC25 146.0
UBE2V1 163.0
BCL2L1 175.0
RPS16 186.0
MAVS 190.0
CHMP1A 196.0
GRSF1 234.0
ATP1B1 239.0
P2RX4 259.0
WIPF3 290.0
NUP85 327.0
CHD3 338.0
GTF2E2 347.0
XRCC6 352.0
PSMD12 373.0
VPS41 389.0
RPL26L1 397.0
RAB5A 398.0
HLA-C 426.0
RPSA 473.0
KPNB1 488.0
GTF2F2 536.0
PSMF1 550.0
HLA-F 589.0
RPL6 651.0
RPL12 711.0
SNRPD2 736.0
VHL 752.0
TAF13 758.0
PSMA2 776.0
UBE2I 794.0
CBX1 812.0
ST3GAL3 852.0
SMAD3 908.0
ELOB 914.0
ELMO2 918.0
DOCK2 995.0
SYT1 1000.0
NUP54 1027.0
PARP16 1055.0
YWHAE 1068.0
PSMD3 1087.0
PDPK1 1090.0
PSMB9 1093.0
IL17F 1103.0
ARPC4 1111.0
RPS15 1149.0
NCKIPSD 1183.0
DAXX 1201.0
CAV1 1218.0
RANBP2 1258.0
ARID4B 1294.0
ADCY3 1298.0
UBB 1320.0
TUSC3 1324.0
GOLGA7 1326.0
RPL41 1365.0
VPS37B 1367.0
H4C8 1444.0
ARPC2 1448.0
GNG2 1545.0
PARP9 1565.0
SAP30L 1574.0
CDH1 1603.0
DAD1 1610.0
H2BC26 1619.0
FUT8 1624.0
CHMP5 1670.0
CCNT2 1685.0
STAM2 1734.0
NUP88 1774.0
SUPT5H 1775.0
NCOR1 1776.0
SYK 1786.0
YWHAB 1797.0
RAN 1799.0
TAF1L 1828.0
RPS10 1837.0
IFNA14 1841.0
PSMA5 1847.0
CDK7 1850.0
POLR2L 1891.0
CHMP7 1896.0
FKBP1A 1933.0
H2AC15 1986.0
AP2A2 1989.0
SOS1 1990.0
PSMB8 2004.0
ST6GAL1 2058.0
RPLP2 2085.0
DVL2 2093.0
PACS1 2117.0
MYO1C 2134.0
NUP210 2136.0
RPL19 2149.0
BTRC 2163.0
MGAT4C 2174.0
PSMA1 2177.0
NRP1 2179.0
H2BC15 2203.0
CREB1 2212.0
PTPN6 2285.0
NPM1 2295.0
ENTPD5 2301.0
HNRNPK 2304.0
EEF2 2310.0
RPS27A 2313.0
ERCC2 2323.0
CTNNB1 2329.0
NUP107 2333.0
NMT2 2340.0
H2BC4 2363.0
RNF213 2368.0
FNTA 2385.0
NDC1 2461.0
NFKB2 2472.0
CD163 2571.0
HDAC3 2573.0
H4C1 2583.0
GPC5 2593.0
DYNC1LI2 2640.0
UBA52 2643.0
CD79B 2659.0
PRKAR2A 2669.0
IFNB1 2718.0
PSMD8 2754.0
NELFCD 2763.0
RPL14 2784.0
RANBP1 2840.0
VPS4A 2877.0
KEAP1 2884.0
NELFE 2912.0
VPS37D 2948.0
TLR9 2952.0
JUN 3045.0
EEF1A1 3054.0
DPEP1 3056.0
ADCY9 3058.0
POLR2H 3091.0
PSME4 3100.0
FEN1 3104.0
GANAB 3147.0
PRKCSH 3152.0
PSMD1 3155.0
TKFC 3169.0
WASF1 3177.0
H2AC20 3179.0
RPL38 3205.0
RPL32 3206.0
MET 3208.0
ANO4 3219.0
CYFIP2 3267.0
B2M 3334.0
RPS12 3386.0
ADCY2 3401.0
FKBP4 3431.0
ATP1B2 3447.0
TAF10 3510.0
MAPK8 3520.0
GNAI1 3557.0
CCNK 3604.0
TMPRSS2 3622.0
SH3GL1 3638.0
IRAK2 3641.0
PRKAR1B 3678.0
NELFA 3698.0
POLR2F 3701.0
MVB12B 3703.0
PTK2 3709.0
ADCY8 3776.0
C3 3779.0
RPS21 3781.0
ELOA 3804.0
TAF5 3845.0
TRAF3 3882.0
ISCU 3959.0
ANO9 3974.0
IRF7 3976.0
FXYD3 4069.0
RPL39L 4074.0
RPS24 4090.0
RPL23A 4115.0
H2BC17 4130.0
SLC25A4 4131.0
SV2A 4180.0
RNF135 4294.0
POLR2E 4421.0
DDX5 4449.0
NUP58 4456.0
MYH9 4460.0
RPS14 4497.0
SNRPE 4508.0
CD247 4556.0
PRKAR2B 4569.0
FXYD6 4580.0
BANF1 4582.0
IFNA8 4593.0
SV2B 4601.0
NOXA1 4615.0
TLR2 4622.0
H2BC11 4657.0
TUBA1B 4671.0
SNRPD1 4714.0
AP1G1 4721.0
H3C1 4735.0
PSMC1 4758.0
G3BP2 4847.0
RPL17 4856.0
SYT2 4900.0
SDC4 4918.0
HDAC1 4949.0
MYO5A 4951.0
IFNA13 4961.0
SDC1 4970.0
RPL7 4972.0
RPS3A 4982.0
TAF11 4988.0
CPSF4 4996.0
PSMB3 5015.0
PARP6 5037.0
NEDD4L 5051.0
HLA-B 5059.0
FZD7 5194.0
HMOX1 5202.0
RPL37 5203.0
ST6GALNAC3 5208.0
SUGT1 5210.0
GNAT3 5218.0
GNG4 5224.0
RPL8 5290.0
ABI1 5365.0
SFPQ 5374.0
H4C5 5401.0
STAT2 5407.0
ITPR3 5421.0
CD9 5434.0
GPC2 5494.0
RPL22L1 5560.0
TUBB1 5561.0
STAT1 5574.0
ST6GALNAC2 5581.0
CRK 5590.0
ANO8 5599.0
MASP2 5613.0
TAF4 5622.0
SRC 5689.0
EGFR 5712.0
PSMC3 5724.0
CREBBP 5734.0
RPS18 5744.0
S1PR1 5776.0
TAB1 5784.0
PSMB5 5798.0
RIGI 5819.0
GTF2H4 5821.0
AKT2 5824.0
ZDHHC11 5835.0
SUZ12 5843.0
MGAT2 5907.5
RPL36AL 5907.5
HAVCR1 5944.0
CHMP4B 5954.0
RPS13 6012.0
RPL31 6025.0
RPS5 6091.0
RPS28 6113.0
AGRN 6226.0
CHD4 6248.0
RPL3 6271.0
NT5E 6339.0
ANTXR1 6359.0
SNRPG 6360.0
SDC2 6383.0
GPC6 6397.0
H2AC6 6426.0
SH3GL3 6459.0
NOS2 6481.0
TCEA1 6529.0
HLA-E 6601.0
IMPDH2 6606.0
RPS7 6631.0
HGS 6652.0
MYO10 6725.0
BAIAP2 6744.0
DOCK1 6775.0
DVL3 6786.0
ANO1 6790.0
ARPC1A 6795.0
RPLP0 6807.0
HLA-G 6850.0
GPC1 6866.0
MTA3 6867.0
NUP205 6912.0
AP2S1 6934.0
PARP1 6975.0
CD4 7022.0
RPL7A 7052.0
PARP10 7057.0
ANO7 7071.0
KPNA2 7126.0
WASF3 7143.0
TPR 7154.0
CCNT1 7156.0
PLCG1 7235.0
VPS25 7242.0
RPS2 7273.0
PKLR 7374.0
RCAN3 7418.0
GNAZ 7481.0
NLRP12 7494.0
ADCY1 7658.0
NUP62 7697.0
IKBKE 7715.0
CYFIP1 7726.0
ADCY6 7800.0
DDOST 7801.0
PARP8 7932.0
MAPK3 7947.0
CD28 7952.0
TAF6 7963.0
RPS11 7972.0
GNG13 8027.0
ANO2 8038.0
SERPINE1 8055.0
POLR2D 8105.0
NOXO1 8200.0
STX1B 8265.0
PSMD2 8298.0
SEH1L 8440.0
HSPG2 8495.0
WIPF2 8508.0
RPL36 8538.0
RNMT 8555.0
H2AC13 8584.0
ZDHHC8 8621.0
RPS3 8628.0
ATP1A3 8636.0
IFNA7 8666.0
VAV2 8721.0
IFNA1 8879.0
ATP1A4 8915.0
PSMA8 8939.0
IFNA5 8942.0
GGT5 8961.0
DYNLL2 9125.0
ATP1A2 9211.0
H2AC11 9249.0
BLNK 9343.0
IFNA16 9377.0
IFNA6 9549.0
MASP1 9581.0
ADCY5 9644.0
GNB3 9683.0
RPL3L 10001.0
FXYD4 10011.0
LCK 10052.0
IL17A 10091.0
RPL13A 10152.5
SFN 10169.0
IL1A 10212.0
PSMB11 10222.0
POLR2J 10234.0
CORO1A 10410.0
CRB3 10610.0
PDCD1 10802.0
MBL2 10846.0
TUBB8 10871.0
GNGT2 10884.0
CD8B 10887.0
CD3G 10960.0



REACTOME_MEMBRANE_TRAFFICKING

REACTOME_MEMBRANE_TRAFFICKING
374
set REACTOME_MEMBRANE_TRAFFICKING
setSize 603
pANOVA 4.54e-10
s.dist -0.149
p.adjustANOVA 4.38e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
AREG -10981
AVP -10848
RABGAP1 -10670
TOR1A -10657
GRK2 -10571
CTSZ -10474
MON1A -10422
TRAPPC3 -10403
ANKRD28 -10373
EPGN -10353
TUBA3D -10346
CLINT1 -10326
TRAPPC10 -10290
TBC1D2 -10252
DCTN2 -10239
CD59 -10212
YWHAG -10207
HPS4 -10201
ARRB1 -10157
TUBB4B -10078

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AREG -10981
AVP -10848
RABGAP1 -10670
TOR1A -10657
GRK2 -10571
CTSZ -10474
MON1A -10422
TRAPPC3 -10403
ANKRD28 -10373
EPGN -10353
TUBA3D -10346
CLINT1 -10326
TRAPPC10 -10290
TBC1D2 -10252
DCTN2 -10239
CD59 -10212
YWHAG -10207
HPS4 -10201
ARRB1 -10157
TUBB4B -10078
RACGAP1 -10072
TMED2 -9959
PACSIN2 -9948
RIN3 -9932
SLC18A3 -9904
BLOC1S1 -9891
SCARB2 -9884
RAB13 -9859
COPS5 -9794
AP4S1 -9725
PICALM -9587
UBC -9558
RAC1 -9520
EREG -9500
DYNLL1 -9489
WASL -9476
COPS7A -9475
STX10 -9463
DYNC1LI1 -9445
STX5 -9365
SORT1 -9356
NECAP1 -9248
NAPA -9160
ARF3 -9134
COPS2 -9132
HSPA8 -9110
RAB3A -9107
TMED10 -9047
TRAPPC6B -9014
RAB18 -8986
ARF1 -8984
RAB8A -8934
GOSR1 -8917
TBC1D13 -8907
VPS53 -8892
VAMP8 -8876
KIF27 -8869
DENND3 -8865
KIFC2 -8844
MIA2 -8834
SEC24A -8812
TUBB4A -8809
BIN1 -8738
CHMP4A -8725
RAB14 -8674
ANKRD27 -8671
GABARAP -8629
GOLGB1 -8626
TMF1 -8581
KIFAP3 -8551
GAPVD1 -8548
TGFA -8513
VPS54 -8501
DNM3 -8428
GJA1 -8427
FTH1 -8414
KIF21B -8413
GCC1 -8409
CALM1 -8399
TBC1D10A -8371
RAB32 -8213
VPS37C -8205
PIP5K1C -8088
SNX18 -8026
TMED3 -8012
GJA9 -7934
AP1S1 -7907
FCHO1 -7899
TMED7 -7896
STAM -7881
COPS3 -7856
ARF6 -7839
KIF2C -7797
KIF21A -7737
TBC1D15 -7728
CHRM2 -7713
EPS15 -7704
COPB2 -7633
RAB27B -7537
SURF4 -7475
CBL -7394
COG3 -7385
CHMP2B -7324
SYNJ1 -7301
VAMP4 -7290
KDELR1 -7280
NECAP2 -7276
SAR1B -7270
DENND1B -7256
CYTH4 -7250
GORASP1 -7243
DNM2 -7164
RHOBTB3 -7136
GALNT1 -7079
LNPEP -7076
FNBP1 -7052
OPTN -7047
COPS4 -6973
SEC24D -6903
MAP1LC3B -6900
TSG101 -6877
TUBAL3 -6859
COG1 -6840
STXBP3 -6828
TUBA4A -6826
SNAP23 -6823
NAPG -6808
KIF5B -6805
AP1M2 -6763
RINT1 -6701
CPD -6684
FTL -6608
COPG1 -6605
DYNC1I2 -6523
TBC1D7 -6499
TUBB3 -6481
RAB27A -6480
HBEGF -6448
TUBA4B -6407
YWHAH -6318
TPD52 -6284
STX17 -6260
VPS51 -6240
DENND5A -6234
MAN2A1 -6229
TRAPPC13 -6218
KIF13B -6178
YWHAZ -6164
RAB3GAP2 -6160
VPS36 -6155
RALGAPA2 -6147
KIF2B -6144
SEC13 -6136
RAB31 -6084
ACTR1A -6083
TUBA1A -6069
LDLR -6061
RAB10 -5924
SEC23A -5922
ACBD3 -5816
TOR1B -5738
PAFAH1B1 -5709
ITSN2 -5658
ACTR2 -5655
SEC22A -5585
RAB1A -5565
CLTA -5506
APP -5475
SEC31A -5444
COPA -5440
GBF1 -5436
AGFG1 -5414
TUBB2A -5397
TFG -5371
USP6NL -5348
TBC1D14 -5306
DCTN6 -5234
COPS6 -5228
VPS28 -5222
DENND4A -5198
RAB36 -5196
ARFIP2 -5191
AP3B1 -5145
RAB7A -5134
AP2M1 -5107
NBAS -5104
ARRB2 -5102
CHMP6 -5085
RAB1B -5084
ACTG1 -5045
EXOC5 -5006
CNIH1 -5002
PLA2G6 -4913
ANK3 -4879
CUX1 -4878
AP4B1 -4860
PAFAH1B3 -4857
RAB38 -4844
KIF16B -4819
GGA3 -4794
VPS37A -4694
ARFGAP3 -4646
MAN1A1 -4644
ULK1 -4639
RAB8B -4595
BLOC1S4 -4591
TUBB6 -4561
AKT1 -4393
PRKAB1 -4382
FOLR1 -4374
PIK3C2A -4361
DENND4B -4352
VPS4B -4332
DYNC1H1 -4301
SNAPIN -4284
KDELR3 -4232
HPS1 -4185
GRB2 -4184
AP2B1 -4081
F5 -4071
EXOC6 -4062
RAB43 -4050
SNX5 -4046
GOLGA4 -4043
SYTL1 -4001
TJP1 -3989
ALPP -3948
AP1G2 -3903
TBC1D1 -3877
CHMP2A -3860
EPN1 -3834
KDELR2 -3830
DENND4C -3811
SH3GL2 -3804
GOLGA2 -3802
RALGAPB -3800
AP2A1 -3781
HIP1 -3760
AGTR1 -3742
TRAPPC6A -3667
MVB12A -3624
AAK1 -3619
NAPB -3603
AKT3 -3595
SEC24C -3587
ARPC3 -3530
KIF22 -3529
LMAN1 -3525
SYNJ2 -3524
GJD3 -3523
VTA1 -3517
DENND6A -3511
DENND1A -3503
LMAN2L -3494
KIF18A -3490
IGF2R -3375
COPB1 -3302
DCTN4 -3208
KIF1B -3198
GJB2 -3190
TUBA1C -3186
SYS1 -3166
VAMP2 -3158
KIF20B -3126
SPTBN1 -3118
UBAP1 -3098
AP1M1 -3083
KIAA0319 -2961
COPS8 -2952
ARFRP1 -2934
CLTC -2915
GJD4 -2904
VAMP3 -2881
TRAPPC5 -2822
COG4 -2801
NAA38 -2797
RAB5B -2791
EXOC7 -2772
COPS7B -2697
GNS -2689
MON1B -2688
KIF3B -2685
CAPZA2 -2683
AP1B1 -2672
REPS1 -2635
USO1 -2632
KIF11 -2597
KIF9 -2570
RAB33B -2551
TUBA8 -2524
APOB -2485
NAA30 -2465
MADD -2448
BICD1 -2421
ARPC5 -2287
ACTR3 -2275
SPTAN1 -2199
CHMP4C -2173
DYNC1I1 -2149
COG7 -2146
CENPE -2121
TUBB2B -2109
GJA10 -2064
SEC23IP -2026
DCTN1 -2023
CHMP3 -2000
CYTH2 -1979
PREB -1919
AP4E1 -1880
DNASE2 -1867
STX4 -1845
MAN2A2 -1835
KLC1 -1763
GCC2 -1727
KIF23 -1597
EXOC8 -1583
CSNK1D -1577
SNX2 -1574
TXNDC5 -1573
CAPZB -1568
TBC1D10B -1505
TRAPPC11 -1484
RABGEF1 -1475
CAPZA1 -1452
GABARAPL2 -1438
TBC1D24 -1409
SCOC -1406
M6PR -1405
RAB11A -1382
PPP6C -1377
PRKAG1 -1371
DAB2 -1356
ANK2 -1346
SEC22C -1249
PRKAA2 -1220
GDI2 -1214
GOSR2 -1204
SLC2A8 -1201
FNBP1L -1097
TRAPPC8 -1070
KIF20A -1025
VPS45 -1021
EXOC1 -1004
RAB6A -961
GALNT2 -837
PUM1 -762
CLVS1 -745
ASPSCR1 -718
TRIP10 -643
KLC2 -596
GJB6 -595
COPE -594
COG8 -544
ACTB -471
CYTH1 -433
SGIP1 -416
RIC1 -394
SEC22B -384
TUBA3C -374
SNAP91 -369
RALA -305
SYT11 -267
LMAN2 -232
FCHO2 -206
EPS15L1 -138
TSC1 -111
TRAPPC4 -98
TUBA3E -95
PRKAG2 -89
SEC24B -71
KLC3 -70
GJC2 -68
ARF4 -67
EXOC2 -46
SCFD1 -28
RABEP1 -27
SNF8 -25
MAN1C1 -20
YWHAQ -11
UBQLN1 23
AP1S3 26
MCFD2 29
GOLIM4 65
WNT5A 130
AMPH 154
NEDD8 160
TBC1D20 206
RAB39A 237
GAK 255
KLC4 269
STON2 297
BTC 301
RAB11B 392
RAB5A 398
PPP6R3 477
EXOC4 522
GGA1 545
TBC1D4 599
RAB5C 623
ARFGAP2 654
ALS2 667
PAFAH1B2 687
GJB7 694
CTTN 699
LRP2 713
YKT6 867
CYTH3 890
PACSIN3 941
MYO6 943
SYT1 1000
MIA3 1018
COPZ1 1020
COPG2 1041
YWHAE 1068
DENND5B 1069
TFRC 1092
ARPC4 1111
SBF2 1140
COG2 1148
SNX9 1154
GGA2 1271
UBB 1320
KIF3A 1322
VTI1A 1349
VPS37B 1367
ARPC2 1448
SLC2A4 1464
TRAPPC1 1479
VPS52 1625
CHMP5 1670
DENND2C 1711
STAM2 1734
GOLGA1 1753
YWHAB 1797
COG6 1816
CHMP7 1896
ARCN1 1940
RAB4A 1983
AP2A2 1989
AGPAT3 2031
DVL2 2093
CTSC 2104
SEC16A 2108
MYO1C 2134
RAB35 2139
KIF6 2159
LDLRAP1 2173
STX16 2272
RPS27A 2313
KIF25 2331
BET1L 2379
RINL 2386
GRK3 2443
AP4M1 2486
BET1 2489
KIF15 2519
CLVS2 2569
DYNC1LI2 2640
UBA52 2643
SPTBN4 2646
TMED9 2667
STON1 2733
RAB21 2740
TBC1D17 2745
EGF 2787
TGOLN2 2791
EPN2 2799
SPTA1 2809
RAB3IP 2814
VPS4A 2877
COG5 2921
KIF3C 2942
VPS37D 2948
USE1 3028
DTNBP1 3403
ITSN1 3422
TBC1D10C 3455
ARF5 3512
MAN1A2 3574
KIFC1 3575
BLOC1S3 3582
SH3GL1 3638
MVB12B 3703
TACR1 3746
KIF2A 3843
BLOC1S6 3895
GJD2 4051
DENND1C 4062
TPD52L1 4073
TRAPPC9 4079
PPP6R1 4206
C2CD5 4209
RAB3GAP1 4296
GOLGA5 4319
AP3S1 4333
RIN2 4348
RAB30 4370
BICD2 4377
MYH9 4460
NSF 4491
DNAJC6 4559
KIF1C 4589
TUBA1B 4671
TRAPPC12 4694
AP1G1 4721
CD55 4766
RAB3IL1 4779
ANK1 4865
TSC2 4893
SYT2 4900
HIP1R 4935
MYO5A 4951
STX18 4978
TRIP11 5034
TMEM115 5094
SYT9 5146
ADRB2 5167
GJC1 5324
CNIH2 5432
PLA2G4A 5443
PRKAB2 5499
DENND2D 5526
TUBB1 5561
PACSIN1 5596
SRC 5689
EGFR 5712
NAA35 5754
KIF19 5755
DCTN5 5779
AKT2 5824
KIF26A 5920
CHMP4B 5954
RIN1 6102
GJA4 6157
ZW10 6165
TRAPPC2L 6188
DNM1 6255
GJA3 6260
STX6 6306
GJB3 6328
DENND2A 6348
KIF4B 6448
SH3GL3 6459
ACTR10 6469
RHOQ 6485
LMAN1L 6508
KIF12 6570
TBC1D16 6593
HGS 6652
KIF26B 6735
ARPC1A 6795
SERPINA1 6864
AP2S1 6934
EXOC3 6987
CD4 7022
DENND2B 7047
BNIP1 7055
VPS25 7242
GPS1 7505
CAPZA3 7525
GJA5 7549
RAB12 7564
ARL1 7584
CNIH3 7590
SH3D19 7665
SPTBN2 7669
KIF1A 7672
KIF18B 7685
DCTN3 7804
COPZ2 7836
RGP1 7882
SYT8 7896
SNAP29 7925
RABEPK 7999
CFTR 8023
KIF5A 8065
CLTB 8332
CLTCL1 8339
GRIA1 8366
SBF1 8494
TF 8567
GJB4 8736
ARFGAP1 8891
SEC16B 8958
ALS2CL 8981
DYNLL2 9125
RAB6B 9169
GJA8 9188
FZD4 9228
COL7A1 9254
INS 9345
SPTBN5 9424
SPTB 9535
CHML 9779
PRKAG3 9785
PLIN3 9954
SFN 10169
IL7R 10351
DENND6B 10370
GJB5 10758
TUBB8 10871
CD3G 10960
CD3D 10994



REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION
1024
set REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION
setSize 1356
pANOVA 6.87e-10
s.dist -0.0998
p.adjustANOVA 6.27e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
FCGR3B -10986
AREG -10981
APOL1 -10957
METTL22 -10847
PNPLA2 -10787
NICN1 -10739
H2BC6 -10708
MOGS -10704
NOD1 -10608
PSMB7 -10578
COMMD3 -10537
CALR -10512
NLRP3 -10484
CTSZ -10474
POM121C -10473
CISH -10470
RAB34 -10467
DPH5 -10428
TRAPPC3 -10403
TRIM13 -10397

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FCGR3B -10986.0
AREG -10981.0
APOL1 -10957.0
METTL22 -10847.0
PNPLA2 -10787.0
NICN1 -10739.0
H2BC6 -10708.0
MOGS -10704.0
NOD1 -10608.0
PSMB7 -10578.0
COMMD3 -10537.0
CALR -10512.0
NLRP3 -10484.0
CTSZ -10474.0
POM121C -10473.0
CISH -10470.0
RAB34 -10467.0
DPH5 -10428.0
TRAPPC3 -10403.0
TRIM13 -10397.0
ANKRD28 -10373.0
GALNT3 -10347.0
TUBA3D -10346.0
PIGU -10323.0
TRAPPC10 -10290.0
DCTN2 -10239.0
CD59 -10212.0
ARRB1 -10157.0
IL6 -10121.0
CD52 -10118.0
TUBB4B -10078.0
SOCS3 -10048.0
NOD2 -10042.0
GPLD1 -10040.0
TMED2 -9959.0
RARA -9950.0
H4C3 -9942.0
PIGY -9931.0
COMMD4 -9880.0
NFE2L2 -9875.0
PDIA3 -9862.0
RAB13 -9859.0
B4GALT5 -9844.0
RNF144A -9835.0
NAE1 -9822.0
PGAP1 -9806.0
COPS5 -9794.0
EP300 -9776.0
ST3GAL2 -9716.0
RPN1 -9708.0
NR1H3 -9671.0
SUMO2 -9661.0
CMAS -9646.0
B4GALT6 -9639.0
BMP4 -9630.0
SHISA5 -9608.0
H2BC12 -9581.0
B3GNT5 -9565.0
BLM -9563.0
UBC -9558.0
RNF103 -9544.0
PSMD5 -9539.0
TRIM4 -9532.0
DCAF5 -9522.0
RAB3D -9518.0
TGFBR1 -9514.0
B3GNT8 -9501.0
H4C11 -9492.0
DYNLL1 -9489.0
H4C9 -9486.0
COPS7A -9475.0
DYNC1LI1 -9445.0
CTSA -9402.0
RBBP5 -9393.0
H2BC5 -9371.0
RAET1L -9366.0
STX5 -9365.0
NRIP1 -9352.0
H2AC16 -9348.0
DNMT3B -9346.0
ALG10 -9343.0
DNAJC3 -9320.0
NEURL2 -9309.0
RFT1 -9301.0
BMI1 -9287.0
TPST1 -9276.0
TPST2 -9268.0
B3GNT2 -9259.0
STAMBP -9242.0
ETFBKMT -9236.0
DCAF17 -9235.0
TRAF6 -9223.0
H4C16 -9179.0
RAB2A -9166.0
NAPA -9160.0
ARF3 -9134.0
COPS2 -9132.0
ST8SIA3 -9111.0
HSPA8 -9110.0
RAB3A -9107.0
FBXL15 -9099.0
H2AC4 -9092.0
UBE2E1 -9071.0
GATA3 -9064.0
TMED10 -9047.0
PIGW -9045.0
CANX -9039.0
RAE1 -9026.0
TRAPPC6B -9014.0
SBSPON -8987.0
RAB18 -8986.0
ARF1 -8984.0
COMMD8 -8956.0
RAB8A -8934.0
GOSR1 -8917.0
B4GALT1 -8905.0
WDR48 -8887.0
PIAS1 -8882.0
DDB2 -8878.0
FBXL18 -8861.0
MIA2 -8834.0
KIN -8816.0
SEC24A -8812.0
TUBB4A -8809.0
CBX8 -8780.0
PIGV -8775.0
AGBL2 -8754.0
NPLOC4 -8719.0
NR4A2 -8717.0
RAB14 -8674.0
GOLGB1 -8626.0
PIGX -8619.0
EDEM2 -8585.0
CBX5 -8555.0
TGFA -8513.0
USP4 -8511.0
H2BC1 -8504.0
KAT2B -8472.0
NCOR2 -8471.0
DPH7 -8463.0
MYSM1 -8456.0
DHDDS -8455.0
IGFBP3 -8436.0
SPP1 -8408.0
H4C13 -8401.0
CALM1 -8399.0
MAT2B -8398.0
RAB42 -8369.0
AXIN1 -8331.0
SVBP -8325.0
BTBD1 -8288.0
TOP1 -8282.0
PHC3 -8272.0
LRRC41 -8263.0
H2BC3 -8237.0
PIGO -8236.0
RAB32 -8213.0
FOXK2 -8199.0
CDC34 -8176.0
ACTR5 -8156.0
CDC25A -8146.0
H2BC8 -8108.0
PSME1 -8101.0
STT3A -8094.0
VDAC3 -8081.0
USP21 -8053.0
HIF1A -8044.0
FSTL3 -8040.0
ETFB -8031.0
WDR20 -8025.0
TMED3 -8012.0
PSMA6 -7988.0
ALG8 -7976.0
DCUN1D3 -7971.0
CD109 -7966.0
NCOA2 -7957.0
FBXW9 -7955.0
ARSJ -7946.0
ST3GAL6 -7925.0
CGA -7924.0
UBE2L3 -7914.0
MBD5 -7912.0
TMED7 -7896.0
USP24 -7887.0
STAM -7881.0
CCNF -7872.0
DCUN1D2 -7865.0
COPS3 -7856.0
FN3KRP -7854.0
BIRC3 -7850.0
PCNA -7849.0
NUP50 -7820.0
RBX1 -7781.0
SIAH2 -7779.0
UBXN1 -7778.0
PLAUR -7776.0
PHC1 -7771.0
CDKN2A -7757.0
EIF5A2 -7720.0
KLHL3 -7700.0
GFPT1 -7687.0
CAND1 -7637.0
COPB2 -7633.0
NUP93 -7632.0
UBE2Q2 -7611.0
RAB27B -7537.0
GALNT7 -7535.0
H2BC9 -7522.5
NSMCE1 -7482.0
INO80D -7468.0
MUL1 -7466.0
FBXL19 -7451.0
USP15 -7442.0
AGBL5 -7387.0
COG3 -7385.0
H2AC21 -7374.0
ASB8 -7312.0
HLA-A -7308.0
VNN1 -7295.0
RTN4RL2 -7291.0
DTL -7288.0
KDELR1 -7280.0
AMDHD2 -7272.0
SAR1B -7270.0
POMGNT1 -7264.0
GORASP1 -7243.0
SOCS2 -7240.0
RIPK2 -7234.0
THRA -7212.0
ADAMTS20 -7189.0
DOHH -7187.0
B3GNT4 -7146.0
SLC35C1 -7101.0
CUL3 -7084.0
GALNT1 -7079.0
TRAF2 -7035.0
MGAT4A -7026.0
KLHL5 -7016.0
MGAT4B -7011.0
RNF7 -6997.0
STAMBPL1 -6995.0
H2BC10 -6977.0
USP10 -6976.0
COPS4 -6973.0
UAP1 -6970.0
YOD1 -6967.0
UBE2G2 -6945.0
ADAM10 -6926.0
CUL1 -6904.0
SEC24D -6903.0
TUBAL3 -6859.0
FBXL7 -6851.0
COG1 -6840.0
TUBA4A -6826.0
USP13 -6813.0
NAPG -6808.0
PML -6800.0
H2AC8 -6733.0
EDEM1 -6706.0
FEM1B -6696.0
USP14 -6691.0
UBE2M -6686.0
CUL5 -6662.0
DPP3 -6656.0
USP8 -6641.0
RXRA -6640.0
INO80C -6625.0
COPG1 -6605.0
ASXL2 -6567.0
RWDD3 -6539.0
DDA1 -6526.0
DYNC1I2 -6523.0
H2AC18 -6516.5
H2AC19 -6516.5
EIF5A -6503.0
SEL1L -6501.0
DNAJC24 -6492.0
TUBB3 -6481.0
RAB27A -6480.0
RNF181 -6468.0
SLC17A5 -6465.0
GCNT4 -6446.0
NSMCE2 -6433.0
TFAP2A -6427.0
ADAMTS10 -6418.0
TNKS2 -6408.0
TUBA4B -6407.0
PSMD13 -6393.0
PPARG -6392.0
RAB37 -6372.0
ALG6 -6352.0
ASB13 -6345.0
FUCA1 -6344.0
LHB -6341.0
NUDT14 -6331.0
WAC -6324.0
IDE -6323.0
ARSK -6321.0
PIGK -6313.0
H2AC1 -6275.0
TNKS -6268.0
GALNT12 -6265.0
STX17 -6260.0
UBE2W -6258.0
FOXK1 -6256.0
MAN2A1 -6229.0
TTLL5 -6226.0
PSMC6 -6219.0
SMAD7 -6202.0
ST3GAL4 -6174.0
RAD23A -6169.0
SEC13 -6136.0
PEX5 -6134.0
PSME2 -6132.0
H2BC14 -6126.0
SCG3 -6115.0
RAB31 -6084.0
ACTR1A -6083.0
FBXW11 -6079.0
XRCC4 -6070.0
TUBA1A -6069.0
UBA6 -6066.0
SENP1 -6051.0
ERCC8 -6036.0
USP25 -6033.0
NUP155 -5935.0
RAB10 -5924.0
SEC23A -5922.0
FOXL2 -5907.0
DCAF8 -5904.0
UBE2K -5898.0
SUDS3 -5886.0
RNF2 -5882.0
GALNT17 -5879.0
NRN1 -5873.0
AURKA -5849.0
RHOT1 -5836.0
POLB -5803.0
MBD6 -5802.0
ATXN7 -5790.0
PIGB -5787.0
BARD1 -5779.0
COMMD2 -5765.0
PIGQ -5694.0
IGFBP4 -5688.0
PTEN -5677.0
AGTPBP1 -5656.0
GGCX -5646.0
PIGN -5634.0
CKAP4 -5628.0
GNE -5595.0
SEC22A -5585.0
CDH2 -5584.0
TOPORS -5581.0
RNF5 -5578.0
RAB1A -5565.0
USP30 -5541.0
HDAC2 -5534.0
DCUN1D1 -5525.0
GALNT5 -5520.0
MBTPS1 -5476.0
APP -5475.0
RHOA -5450.0
SEC31A -5444.0
COPA -5440.0
GBF1 -5436.0
MAP3K7 -5435.0
UBXN7 -5421.0
USP47 -5412.0
TUBB2A -5397.0
OTUB1 -5394.0
PIGF -5385.0
CBX2 -5379.0
TFG -5371.0
H2AC7 -5340.5
H2BC7 -5340.5
NUP153 -5310.0
COMMD1 -5304.0
KLHL42 -5301.0
POM121 -5300.0
TRIM28 -5298.0
RAB19 -5290.0
APOA1 -5268.0
FBXO7 -5239.0
DCTN6 -5234.0
COPS6 -5228.0
ULBP2 -5205.0
H2AC12 -5204.0
RAB36 -5196.0
NR3C2 -5189.0
SRD5A3 -5180.0
AGBL3 -5159.0
ASB1 -5150.0
YY1 -5148.0
UCHL3 -5147.0
RAB7A -5134.0
ARSB -5118.0
ARRB2 -5102.0
NAGK -5092.0
ZRANB1 -5090.0
RAB1B -5084.0
USP5 -5053.0
CDKN1A -5005.0
CNIH1 -5002.0
CCP110 -4990.0
BABAM2 -4972.0
COP1 -4967.0
FBXW2 -4950.0
CYLD -4946.0
GALNT6 -4928.0
ANK3 -4879.0
SP100 -4861.0
RAB38 -4844.0
NFKBIA -4831.0
NPL -4806.0
UBE2G1 -4788.0
FBXL8 -4781.0
FBXO30 -4775.0
SELENOS -4764.0
ELOC -4748.0
FBXO31 -4732.0
MVD -4730.0
ABRAXAS1 -4723.0
SPSB2 -4721.0
VCP -4679.0
VDR -4667.0
ARFGAP3 -4646.0
MAN1A1 -4644.0
PROS1 -4616.0
PSMB10 -4606.0
GMPPA -4599.0
RAB8B -4595.0
ST8SIA4 -4565.0
TUBB6 -4561.0
GALNTL5 -4557.0
PENK -4552.0
DPM3 -4545.0
USP37 -4536.0
IGFBP5 -4514.0
MDGA2 -4507.0
SENP8 -4497.0
KLHL25 -4480.0
VGF -4447.0
PIGG -4434.0
UBE2F -4417.0
FOLR2 -4404.0
IFIH1 -4395.0
FOLR1 -4374.0
TFAP2C -4370.0
B4GALT3 -4359.0
PSMB2 -4344.0
WSB1 -4342.0
ALG10B -4329.0
DYNC1H1 -4301.0
NUS1 -4295.0
ST3GAL1 -4277.0
PEX10 -4274.0
KLHL11 -4266.0
OTUB2 -4246.0
RAB29 -4236.0
KDELR3 -4232.0
RIPK1 -4183.0
RPN2 -4174.0
ST8SIA6 -4158.0
INO80 -4150.0
NUP188 -4141.0
GMDS -4125.0
APC -4118.0
VDAC2 -4110.0
FBXL3 -4090.0
F5 -4071.0
PSMD7 -4057.0
RAB43 -4050.0
PEX14 -4037.0
H4C4 -4007.0
NUP133 -3990.0
DAG1 -3979.0
PMM1 -3942.0
RNF40 -3939.0
PRSS23 -3923.0
PIGS -3844.0
KDELR2 -3830.0
GOLGA2 -3802.0
FEM1C -3787.0
RUVBL1 -3783.0
TOMM70 -3759.0
PIGH -3758.0
RNF152 -3757.0
USP42 -3751.0
UHRF2 -3740.0
MUC12 -3738.0
H2BC21 -3732.0
GALNT13 -3729.0
KLHL21 -3717.0
HDAC7 -3704.0
CAMKMT -3697.0
UBE2D2 -3692.0
ADAMTS18 -3686.0
TRAPPC6A -3667.0
RELA -3661.0
NCOA1 -3650.0
ADAMTS6 -3631.0
NEU3 -3625.0
NAPB -3603.0
SEC24C -3587.0
FBXO11 -3584.0
H4C6 -3568.0
CSF1 -3564.0
ZBTB16 -3550.0
LY6H -3544.0
CDC73 -3539.0
LMAN1 -3525.0
LMAN2L -3494.0
MLEC -3475.0
SAFB -3464.0
B4GALT2 -3460.0
UBE2N -3431.0
LYPD5 -3419.0
PSMA7 -3416.0
DPH6 -3410.0
NR3C1 -3398.0
RAB25 -3385.0
H2AC14 -3377.0
CNTN3 -3360.0
GPAA1 -3337.0
PEX13 -3311.0
COPB1 -3302.0
XPC -3276.0
CUL4A -3270.0
HIC1 -3261.0
PSME3 -3245.0
BECN1 -3236.0
SKP1 -3229.0
METTL21A -3218.0
DCTN4 -3208.0
ADAMTSL5 -3199.0
PALB2 -3191.0
TUBA1C -3186.0
GALNT11 -3173.0
NUP42 -3160.0
RAD18 -3144.0
C1GALT1 -3129.0
STAG1 -3119.0
SPTBN1 -3118.0
TP53BP1 -3116.0
PRSS21 -3115.0
FEM1A -3099.0
CALU -3093.0
SMAD2 -3052.0
RAD23B -3034.0
DDB1 -2994.0
COPS8 -2952.0
KBTBD8 -2925.0
HNRNPC -2910.0
MRTFA -2901.0
ING2 -2880.0
AURKB -2861.0
TRAPPC5 -2822.0
CHST10 -2817.0
ART3 -2808.0
COG4 -2801.0
RAB5B -2791.0
PSMC4 -2787.0
SQSTM1 -2777.0
RAB24 -2776.0
SCG2 -2763.0
PRMT3 -2739.0
CDK1 -2730.0
PMM2 -2728.0
CP -2726.0
CCNA1 -2724.0
NUP98 -2703.0
COPS7B -2697.0
CAPZA2 -2683.0
SPARCL1 -2674.0
CCDC8 -2657.0
AXIN2 -2653.0
TADA3 -2648.0
USO1 -2632.0
CST3 -2614.0
RAB2B -2552.0
RAB33B -2551.0
DCAF16 -2547.0
NSMCE3 -2540.0
TUBA8 -2524.0
FBXW4 -2515.0
NUP160 -2508.0
USP20 -2506.0
INCENP -2499.0
APOB -2485.0
FBXO4 -2478.0
UBA2 -2473.0
FBXL12 -2456.0
FBXL4 -2454.0
ST6GALNAC4 -2442.0
UBA3 -2439.0
TRIM27 -2433.0
BCL10 -2415.0
CTR9 -2373.0
MGAT1 -2370.0
GALNT10 -2366.0
TGFB1 -2362.0
NGLY1 -2361.0
ALG3 -2335.0
UIMC1 -2261.0
MPI -2232.0
SPTAN1 -2199.0
DCUN1D4 -2195.0
OTULIN -2187.0
SEM1 -2183.0
PTRH2 -2170.0
UBE2T -2157.0
DYNC1I1 -2149.0
COG7 -2146.0
PIGC -2117.0
TUBB2B -2109.0
PEX12 -2094.0
SUMO1 -2089.0
MYC -2072.0
RTF1 -2066.0
NUP35 -2059.0
FPGT -2051.0
SEC23IP -2026.0
DCTN1 -2023.0
PSMB6 -1996.0
PSMD14 -1965.0
FURIN -1963.0
DPH3 -1959.0
DERL1 -1955.0
FBXL5 -1948.0
USP3 -1924.0
PREB -1919.0
LMO7 -1899.0
ALPG -1858.0
TTLL4 -1846.0
MAN2A2 -1835.0
ASXL1 -1833.0
RNF185 -1825.0
ALG2 -1819.0
SMAD4 -1810.0
BABAM1 -1800.0
ARSG -1750.0
CUL2 -1702.0
ADAMTSL1 -1696.0
B3GNTL1 -1686.0
TNFAIP3 -1669.0
RRAGA -1665.0
ADAMTS16 -1664.0
OS9 -1652.0
TPGS1 -1635.0
DCAF7 -1631.0
KLHL20 -1626.0
RAD21 -1610.0
OTUD3 -1591.0
B4GALT4 -1586.0
CSNK1D -1577.0
SERPINC1 -1576.0
CAPZB -1568.0
HIPK2 -1566.0
DPM1 -1536.0
ALG9 -1528.0
MAN1B1 -1523.0
SOCS5 -1504.0
ASB4 -1477.0
B3GNT3 -1471.0
PSMD9 -1453.0
CAPZA1 -1452.0
HSP90B1 -1447.0
PHC2 -1440.0
NEGR1 -1424.0
SIN3A -1392.0
WSB2 -1386.0
RAB11A -1382.0
PPP6C -1377.0
USP48 -1373.0
USP22 -1360.0
PSMC5 -1352.0
ANK2 -1346.0
SMC3 -1334.0
TRIM25 -1291.0
RAB26 -1286.0
IGFBP7 -1265.0
SEC22C -1249.0
ADAMTS17 -1248.0
THSD7B -1242.0
PDIA6 -1227.0
SPON1 -1222.0
GOSR2 -1204.0
PSMB4 -1200.0
MTA1 -1189.0
KTN1 -1164.0
MARCHF6 -1141.0
KLHL9 -1132.0
H4C12 -1092.0
MDM2 -1085.0
UCHL5 -1051.0
L3MBTL2 -1031.0
LTBP1 -1015.0
COMMD6 -1011.0
FN1 -1010.0
PSMA3 -989.0
DCAF11 -980.0
RAB6A -961.0
RAB40C -938.0
EEF1AKMT2 -932.0
NR1I2 -924.0
PARK7 -914.0
AAAS -910.0
PCSK9 -895.0
USP33 -884.0
PEX2 -875.0
MUC6 -873.0
RING1 -863.0
DCAF10 -861.0
H4C2 -859.0
PSMC2 -840.0
MANEA -838.0
GALNT2 -837.0
TP53 -831.0
NR5A2 -826.0
NUP37 -825.0
FBXO44 -816.0
MEPE -796.0
TGFBR2 -747.0
SKP2 -722.0
UBE2E3 -717.0
UBE2C -706.0
SUMF2 -690.0
ADAMTS3 -685.0
PSMD6 -684.0
USP2 -680.0
RANGAP1 -663.0
ASB3 -660.0
UFD1 -637.0
MEN1 -632.0
TNIP1 -608.0
USP44 -605.0
BTBD6 -597.0
COPE -594.0
PIAS4 -575.0
COG8 -544.0
ADAMTS1 -541.0
NUP43 -528.0
PSMD11 -524.0
NUP214 -489.0
PSMB1 -483.0
ACTB -471.0
LRR1 -451.0
TPGS2 -442.0
VCPKMT -432.0
OPCML -402.0
PSMA4 -398.0
ANKRD9 -395.0
SEC22B -384.0
PIGM -378.0
TUBA3C -374.0
TNIP3 -337.0
DERL2 -335.0
USP16 -320.0
NUB1 -280.0
SATB2 -271.0
LMAN2 -232.0
COMMD5 -218.0
MPDU1 -154.0
POMK -141.0
SMURF2 -126.0
PIGP -120.0
H2AC17 -112.0
ZNF350 -101.0
ART4 -99.0
TRAPPC4 -98.0
TUBA3E -95.0
MDM4 -86.0
TTLL12 -77.0
SEC24B -71.0
ARF4 -67.0
SYVN1 -66.0
SCFD1 -28.0
MAN1C1 -20.0
SCMH1 -17.0
H2BC13 1.0
UBE2S 7.0
FBN1 8.0
RAB15 12.0
MBD1 15.0
MCFD2 29.0
USP19 54.0
PSMD4 55.0
VCPIP1 56.0
RAB4B 70.0
DPAGT1 100.0
CNTN5 108.0
MGAT5 132.0
P4HB 134.0
HDAC4 140.0
H2AC25 146.0
WDR5 156.0
NEDD8 160.0
NR1H4 161.0
POMGNT2 162.0
FBXO22 164.0
MUC3A 176.0
MAVS 190.0
TBC1D20 206.0
UGGT1 212.0
RAB39A 237.0
DCAF13 243.0
SHPRH 256.0
ACTL6A 268.0
LARGE2 276.0
SKIC8 283.0
PPARA 293.0
LAMB1 317.0
NUP85 327.0
CHST8 334.0
CHD3 338.0
MUC13 348.0
PSMD12 373.0
RAB11B 392.0
RAB5A 398.0
ASB14 401.0
MUC15 411.0
BRCA1 456.0
FUCA2 472.0
PPP6R3 477.0
BAP1 506.0
RABGGTA 515.0
EPAS1 547.0
PSMF1 550.0
RAD52 585.0
B4GALNT2 610.0
RAB5C 623.0
OTUD7B 629.0
RECK 649.0
ARFGAP2 654.0
C4A 659.5
ACTR8 706.0
MDGA1 707.0
PRKDC 733.0
MUC5B 741.0
DOLK 742.0
VHL 752.0
UBE2H 772.0
PSMA2 776.0
UBE2I 794.0
LRRC49 801.0
USP49 808.0
MUC1 810.0
DDX17 836.0
ST3GAL3 852.0
FBXW8 858.0
RAB20 859.0
YKT6 867.0
ALG5 879.0
UBE2J2 887.0
SUMF1 899.0
SMAD3 908.0
ELOB 914.0
LEO1 931.0
FBXW10 940.0
HIF3A 948.0
PCGF2 970.0
FBXL13 982.0
ARSA 989.0
TULP4 1007.0
FBXW7 1013.0
MIA3 1018.0
COPZ1 1020.0
NUP54 1027.0
COPG2 1041.0
ASGR2 1042.0
PSMD3 1087.0
PSMB9 1093.0
TMEM132A 1095.0
COG2 1148.0
DAXX 1201.0
MDC1 1223.0
RANBP2 1258.0
QSOX1 1274.0
NEU1 1282.0
RNF146 1299.0
UBB 1320.0
TUSC3 1324.0
FUOM 1332.0
ST6GAL2 1360.0
FBXO6 1361.0
SMC5 1396.0
AMTN 1415.0
H4C8 1444.0
TTLL3 1461.0
GCNT7 1466.0
TRAPPC1 1479.0
ST6GALNAC6 1488.0
HERC2 1503.0
GALNT9 1516.0
UBE2D3 1527.0
TTLL7 1546.0
WRN 1553.0
VDAC1 1555.0
COMMD7 1558.0
DNMT3A 1573.0
SPON2 1596.0
DAD1 1610.0
H2BC26 1619.0
FUT8 1624.0
HLTF 1642.0
LAMC1 1695.0
STAM2 1734.0
MCRS1 1757.0
RAB3C 1760.0
ADAMTS7 1769.0
NUP88 1774.0
TOP2A 1778.0
ASB7 1807.0
COG6 1816.0
PSMA5 1847.0
ADRM1 1849.0
TFPT 1883.0
KLHL22 1915.0
LSAMP 1923.0
UBE2V2 1929.0
ARCN1 1940.0
SENP2 1946.0
INO80E 1980.0
RAB4A 1983.0
H2AC15 1986.0
PSMB8 2004.0
SEMA5A 2006.0
ST6GAL1 2058.0
FUT3 2072.0
SENP5 2075.0
CTSC 2104.0
SEC16A 2108.0
NFRKB 2125.0
NUP210 2136.0
RAB35 2139.0
BTRC 2163.0
MGAT4C 2174.0
PSMA1 2177.0
SP3 2183.0
H2BC15 2203.0
NPM1 2295.0
SMAD1 2302.0
HNRNPK 2304.0
EEF2 2310.0
FN3K 2311.0
RPS27A 2313.0
NUP107 2333.0
KCTD6 2338.0
H2BC4 2363.0
TFAP2B 2366.0
B3GNT9 2378.0
BET1L 2379.0
USP7 2400.0
NDC1 2461.0
NFKB2 2472.0
BET1 2489.0
EDEM3 2525.0
H4C1 2583.0
FBXO9 2584.0
EID3 2589.0
LYPD1 2599.0
PIAS3 2629.0
THY1 2638.0
DYNC1LI2 2640.0
UBA52 2643.0
SPTBN4 2646.0
EEF2KMT 2652.0
COMMD10 2665.0
TMED9 2667.0
UGGT2 2670.0
THRB 2680.0
CUL7 2681.0
ATXN3 2716.0
TRRAP 2723.0
RORA 2729.0
RCE1 2732.0
RAB21 2740.0
USP18 2744.0
PSMD8 2754.0
CBX4 2785.0
TGOLN2 2791.0
USP12 2800.0
SPTA1 2809.0
VNN2 2818.0
EEF1AKMT1 2837.0
MELTF 2847.0
GALNTL6 2871.0
APLP2 2876.0
PGM3 2883.0
KEAP1 2884.0
CDC20 2914.0
COG5 2921.0
TTLL1 2968.0
CTBP1 2970.0
SERPIND1 2993.0
VCAN 3001.0
HRC 3008.0
NUCB1 3012.0
GFUS 3013.0
PIGL 3029.0
NR2C1 3044.0
EEF1A1 3054.0
FBXO15 3061.0
ALG14 3063.0
TOP2B 3083.0
JOSD1 3099.0
PSME4 3100.0
KBTBD6 3129.0
NOTUM 3142.0
GANAB 3147.0
PRKCSH 3152.0
PSMD1 3155.0
H2AC20 3179.0
USP34 3189.0
B3GALNT2 3228.0
RABGGTB 3261.0
ADAMTS4 3263.0
PGR 3276.0
ADAMTS9 3362.0
STC2 3396.0
EVA1A 3404.0
LAMB2 3410.0
B3GLCT 3427.0
TTL 3441.0
FKBP8 3476.0
TAF10 3510.0
ARF5 3512.0
CCN1 3543.0
MAN1A2 3574.0
FBXO32 3579.0
NTNG1 3609.0
NSMCE4A 3626.0
TNC 3659.0
ADAMTS12 3679.0
USP28 3712.0
MATN3 3734.0
CPM 3742.0
C3 3779.0
ASB18 3795.0
THSD7A 3817.0
RCN1 3841.0
AMFR 3860.0
TRAF3 3882.0
ALG11 3900.0
KAT2A 3907.0
ASB5 3926.0
DCAF6 3928.0
RAET1G 3939.0
PROZ 3978.0
PRKN 3999.0
ALB 4005.0
NTNG2 4011.0
PSCA 4035.0
SLC35A1 4066.0
TRAPPC9 4079.0
H2BC17 4130.0
DCUN1D5 4153.0
VASH2 4170.0
TOMM20 4183.0
PPP6R1 4206.0
TDG 4222.0
ST8SIA1 4240.0
TTLL10 4249.0
PRND 4258.0
UBE2R2 4284.0
RNF135 4294.0
NOP58 4321.0
PAF1 4354.0
DCAF4 4365.0
RAB30 4370.0
ADAMTSL3 4443.0
DDX5 4449.0
NUP58 4456.0
RNF168 4485.0
SATB1 4489.0
NSF 4491.0
FBXO17 4517.0
MITF 4614.0
FBXO2 4621.0
INO80B 4630.0
DPM2 4633.0
FBXL16 4636.0
H2BC11 4657.0
FBXL20 4660.0
TUBA1B 4671.0
LY6K 4685.0
SPSB3 4704.0
AGBL4 4712.0
SOCS6 4728.0
PSMC1 4758.0
CD55 4766.0
ESR1 4769.0
UMOD 4826.0
SMC6 4849.0
COMMD9 4852.0
ANK1 4865.0
BGLAP 4869.0
GALNT16 4887.0
NTM 4895.0
ASB2 4921.0
HDAC1 4949.0
ADAMTS15 4971.0
RTN4RL1 4985.0
SUMO3 5005.0
PSMB3 5015.0
ADAMTS5 5018.0
RAB23 5027.0
FAM20A 5064.0
NANS 5072.0
DHPS 5089.0
TMEM115 5094.0
THBS2 5102.0
PPARGC1A 5113.0
NR1H2 5134.0
ADAMTSL4 5165.0
WFS1 5166.0
ADRB2 5167.0
THSD1 5182.0
NANP 5187.0
ST6GALNAC3 5208.0
CCNA2 5235.0
UBE2Z 5243.0
MFGE8 5244.0
SPSB1 5249.0
TADA2B 5305.0
FCSK 5343.0
VWA1 5348.0
GALNT4 5364.0
ALPL 5373.0
H4C5 5401.0
RNF123 5418.0
CNIH2 5432.0
GFPT2 5466.0
GAN 5481.0
UBE2B 5554.0
TUBB1 5561.0
ST6GALNAC5 5573.0
ST6GALNAC2 5581.0
ANO8 5599.0
PIGT 5600.0
POMT2 5618.0
GPIHBP1 5640.0
TMEM129 5641.0
FBXO27 5672.0
WDTC1 5687.0
PSMC3 5724.0
CREBBP 5734.0
GLB1 5752.0
DCTN5 5779.0
TAB1 5784.0
PSMB5 5798.0
ZNF131 5800.0
RIGI 5819.0
SUZ12 5843.0
RAB22A 5844.0
THBS1 5846.0
KLHL2 5860.0
APOE 5875.0
MGAT2 5907.5
GCNT1 5933.0
MUC20 5948.0
KCTD7 5963.0
FSTL1 5964.0
RAB44 5981.0
F2 5998.0
ADAMTS2 6020.0
AGBL1 6051.0
PRSS41 6057.0
NEU2 6067.0
CUL9 6090.0
AFP 6099.0
FBXO40 6100.0
CHGB 6135.0
FBXL22 6183.0
TRAPPC2L 6188.0
ARSI 6192.0
SAE1 6252.0
RNF20 6279.0
DPH1 6317.0
GMPPB 6333.0
CNTN4 6354.0
ADAMTS19 6376.0
SDC2 6383.0
ALG12 6394.0
SNX3 6408.0
H2AC6 6426.0
ACTR10 6469.0
DPH2 6472.0
NRN1L 6503.0
LMAN1L 6508.0
BPIFB2 6511.0
BST1 6562.0
PUM2 6642.0
HGS 6652.0
SSPOP 6671.0
ST8SIA5 6705.0
CHST4 6716.0
DNMT1 6745.0
PLET1 6747.0
MUC7 6748.0
TTLL11 6800.0
SERPINA1 6864.0
ADAMTS13 6869.0
TECTA 6876.0
TTLL8 6889.0
NUP205 6912.0
MUCL1 6913.0
JOSD2 6930.0
PIGZ 6944.0
PARP1 6975.0
RAB40B 6982.0
FGG 7005.0
ICMT 7023.0
ASB15 7044.0
UBE2D1 7063.0
RPA1 7064.0
BIRC2 7080.0
TPR 7154.0
POFUT2 7172.0
MUC21 7244.0
PIAS2 7256.0
LGALS1 7266.0
RPS2 7273.0
CDCA8 7291.0
IGFBP1 7302.0
TTLL9 7315.0
ASGR1 7332.0
PTP4A2 7356.0
BIRC5 7359.0
CLSPN 7366.0
KBTBD7 7367.0
OBSL1 7375.0
LY6E 7407.0
GNPNAT1 7429.0
NEU4 7462.0
OTOA 7480.0
GPS1 7505.0
ST3GAL5 7524.0
CAPZA3 7525.0
ENGASE 7543.0
RAB12 7564.0
GCNT3 7567.0
SPSB4 7568.0
OTUD7A 7571.0
CNIH3 7590.0
FGF23 7592.0
ASB6 7603.0
TECTB 7644.0
MUC17 7650.0
FGA 7652.0
SEMA5B 7655.0
SPTBN2 7669.0
MUC4 7673.0
NUP62 7697.0
VASH1 7711.0
FAM20C 7714.0
IKBKE 7715.0
NR5A1 7725.0
IZUMO1R 7792.0
DDOST 7801.0
DCTN3 7804.0
COPZ2 7836.0
DOLPP1 7877.0
ASB10 7971.0
IL33 8001.0
FBXW5 8019.0
CFTR 8023.0
FBXO10 8030.0
RAB3B 8073.0
RAB17 8076.0
POMT1 8167.0
RNF139 8220.0
ADAMTS8 8231.0
KDM1B 8241.0
THSD4 8266.0
B4GAT1 8287.0
PSMD2 8298.0
F10 8303.0
LARGE1 8318.0
TNIP2 8347.0
GRIA1 8366.0
SEH1L 8440.0
ASB17 8463.0
MXRA8 8549.0
GALNT8 8556.0
TF 8567.0
H2AC13 8584.0
A4GNT 8604.0
F7 8607.0
FBXO21 8647.0
FBXL14 8664.0
GALNT15 8667.0
KLHL41 8728.0
ASB16 8735.0
ARFGAP1 8891.0
PSMA8 8939.0
SEC16B 8958.0
GALNT18 9005.0
ITIH2 9006.0
DMP1 9025.0
PROC 9041.0
ADAMTSL2 9052.0
B3GNT7 9100.0
DYNLL2 9125.0
CEACAM5 9133.0
RAB6B 9169.0
GP2 9210.0
SPP2 9244.0
H2AC11 9249.0
COL7A1 9254.0
LY6G6D 9258.0
TTLL13 9260.0
APOA2 9329.0
AHSG 9334.0
INS 9345.0
AMBN 9362.0
MGAT3 9420.0
SPTBN5 9424.0
FBXO41 9463.0
MUC16 9470.0
ALG1 9483.0
B3GNT6 9494.0
LY6G6C 9501.0
ALPI 9513.0
SPTB 9535.0
LYPD6B 9559.0
ENAM 9563.0
LYPD4 9611.0
ST8SIA2 9721.0
GALNT14 9731.0
CHML 9779.0
LYPD8 9810.0
GOLM1 9833.0
TTLL6 9900.0
LY6D 9913.0
APOA5 9957.0
MUC5AC 10125.0
ABRAXAS2 10161.0
KNG1 10199.0
UCHL1 10204.0
MSLN 10221.0
PSMB11 10222.0
TEX101 10238.0
SERPINA10 10317.0
CEACAM7 10325.0
UBD 10415.0
ST6GALNAC1 10437.0
ADAMTS14 10449.0
SPACA4 10513.0
LYPD3 10686.0
TTLL2 10696.0
FBXW12 10765.0
LYPD2 10773.0
TUBB8 10871.0
SPRN 10991.0



REACTOME_DNA_REPAIR

REACTOME_DNA_REPAIR
1168
set REACTOME_DNA_REPAIR
setSize 321
pANOVA 2.86e-09
s.dist -0.193
p.adjustANOVA 2.47e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
UBA7 -10772
H2BC6 -10708
MPG -10501
POLR2C -10372
RMI2 -10267
ERCC3 -10242
BRCA2 -10235
H4C3 -9942
COPS5 -9794
EP300 -9776
SUMO2 -9661
SLX4 -9628
MSH6 -9618
H2BC12 -9581
BLM -9563
UBC -9558
NBN -9502
H4C11 -9492
H4C9 -9486
COPS7A -9475

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
UBA7 -10772.0
H2BC6 -10708.0
MPG -10501.0
POLR2C -10372.0
RMI2 -10267.0
ERCC3 -10242.0
BRCA2 -10235.0
H4C3 -9942.0
COPS5 -9794.0
EP300 -9776.0
SUMO2 -9661.0
SLX4 -9628.0
MSH6 -9618.0
H2BC12 -9581.0
BLM -9563.0
UBC -9558.0
NBN -9502.0
H4C11 -9492.0
H4C9 -9486.0
COPS7A -9475.0
H2BC5 -9371.0
SPIDR -9196.0
H4C16 -9179.0
FANCL -9177.0
CHEK1 -9151.0
RAD51D -9148.0
COPS2 -9132.0
H2AC4 -9092.0
UBE2L6 -9089.0
WDR48 -8887.0
PIAS1 -8882.0
DDB2 -8878.0
HUS1 -8871.0
TINF2 -8864.0
NPLOC4 -8719.0
ISG15 -8683.0
ERCC1 -8587.0
H2BC1 -8504.0
H4C13 -8401.0
POLK -8336.0
H2BC3 -8237.0
RAD51AP1 -8168.0
ACTR5 -8156.0
H2BC8 -8108.0
RAD1 -8063.0
CDK2 -8046.0
TDP1 -8030.0
COPS3 -7856.0
PCNA -7849.0
PMS2 -7786.0
RBX1 -7781.0
UBXN1 -7778.0
HMGN1 -7750.0
POLR2K -7697.0
FAAP24 -7645.0
TIMELESS -7563.0
H2AZ1 -7538.0
H2BC9 -7522.5
SIRT6 -7506.0
POLE4 -7505.0
INO80D -7468.0
H2AJ -7338.0
FANCE -7336.0
ATRIP -7316.0
APEX1 -7311.0
DTL -7288.0
POLR2A -7267.0
FANCM -7227.0
XRCC1 -7075.0
H2BC10 -6977.0
USP10 -6976.0
COPS4 -6973.0
AQR -6765.0
H2AC8 -6733.0
INO80C -6625.0
PRPF19 -6624.0
H2AC18 -6516.5
H2AC19 -6516.5
EME2 -6486.0
EYA1 -6442.0
PAXIP1 -6423.0
TDP2 -6334.0
ISY1 -6239.0
RAD23A -6169.0
H2BC14 -6126.0
CCNH -6119.0
FANCG -6114.0
XRCC4 -6070.0
MUS81 -6062.0
LIG3 -6045.0
FTO -6042.0
ERCC8 -6036.0
POLB -5803.0
BARD1 -5779.0
MRE11 -5675.0
LIG1 -5649.0
RNF8 -5619.0
ATM -5608.0
RBBP8 -5574.0
GEN1 -5492.0
DCLRE1A -5484.0
MSH3 -5411.0
H2AC7 -5340.5
H2BC7 -5340.5
POLD3 -5331.0
POLD4 -5312.0
COPS6 -5228.0
CHEK2 -5211.0
MBD4 -5201.0
YY1 -5148.0
NTHL1 -5133.0
KAT5 -5079.0
LIG4 -4996.0
BABAM2 -4972.0
ATR -4921.0
KDM4B -4912.0
ABRAXAS1 -4723.0
RCHY1 -4706.0
VCP -4679.0
POT1 -4645.0
PPP4R2 -4473.0
REV3L -4465.0
ALKBH2 -4427.0
DCLRE1B -4380.0
GTF2H5 -4378.0
ASCC2 -4223.0
INO80 -4150.0
CHD1L -4134.0
ELL -4130.0
H4C4 -4007.0
KDM4A -3935.0
XPA -3930.0
FAAP20 -3870.0
RFC5 -3853.0
BAZ1B -3837.0
RUVBL1 -3783.0
H2BC21 -3732.0
PNKP -3724.0
GTF2H1 -3642.0
NSD2 -3599.0
H4C6 -3568.0
UBE2N -3431.0
H2AC14 -3377.0
XPC -3276.0
CUL4A -3270.0
RAD51 -3266.0
MNAT1 -3244.0
RIF1 -3225.0
PALB2 -3191.0
RFC1 -3189.0
FANCA -3178.0
RAD18 -3144.0
TP53BP1 -3116.0
RAD23B -3034.0
DDB1 -2994.0
COPS8 -2952.0
POLR2I -2893.0
RFC4 -2868.0
RFC3 -2823.0
CCNA1 -2724.0
COPS7B -2697.0
ZNF830 -2680.0
POLR2B -2615.0
GTF2H3 -2584.0
FAAP100 -2414.0
ASCC3 -2327.0
UIMC1 -2261.0
SEM1 -2183.0
UBE2T -2157.0
SUMO1 -2089.0
RAD17 -2076.0
USP45 -1999.0
UVSSA -1956.0
FANCC -1907.0
UNG -1844.0
BABAM1 -1800.0
ALKBH3 -1735.0
TIPIN -1729.0
SMARCA5 -1620.0
TERF1 -1604.0
EXO1 -1398.0
TRIM25 -1291.0
POLR2G -1251.0
DCLRE1C -1178.0
RMI1 -1101.0
H4C12 -1092.0
RHNO1 -1080.0
RAD9B -1016.0
H4C2 -859.0
TP53 -831.0
ALKBH5 -802.0
POLE -777.0
EYA4 -750.0
RAD51B -744.0
NEIL2 -689.0
RTEL1 -657.0
UFD1 -637.0
XRCC5 -615.0
PIAS4 -575.0
ABL1 -558.0
RAD9A -486.0
ACTB -471.0
PARP2 -454.0
MLH1 -367.0
H2BC13 1.0
TERF2IP 79.0
SMUG1 102.0
RNF111 210.0
ACTL6A 268.0
SPRTN 285.0
XRCC6 352.0
ACD 384.5
POLL 407.0
NEIL3 425.0
POLH 429.0
BRCA1 456.0
BAP1 506.0
RAD52 585.0
ACTR8 706.0
PRKDC 733.0
UBE2I 794.0
H3-4 835.0
PARG 1106.0
MDC1 1223.0
UBB 1320.0
H4C8 1444.0
HERC2 1503.0
WRN 1553.0
RPA2 1570.0
H2BC26 1619.0
ASCC1 1643.0
ERCC5 1713.0
MCRS1 1757.0
FANCD2 1800.0
CDK7 1850.0
TFPT 1883.0
POLR2L 1891.0
UBE2V2 1929.0
INO80E 1980.0
POLD2 2071.0
NFRKB 2125.0
PPIE 2138.0
H2BC15 2203.0
POLQ 2247.0
RPS27A 2313.0
ERCC2 2323.0
H2BC4 2363.0
USP7 2400.0
FANCF 2550.0
H4C1 2583.0
BRIP1 2607.0
PIAS3 2629.0
UBA52 2643.0
ADPRS 2682.0
DNA2 2831.0
CENPS 2903.0
RFC2 2936.0
POLR2H 3091.0
FEN1 3104.0
POLE2 3141.0
H2AC20 3179.0
EYA3 3400.0
MAPK8 3520.0
NHEJ1 3591.0
MGMT 3642.0
TERF2 3655.0
POLI 3683.0
POLR2F 3701.0
MSH2 3713.0
REV1 3923.0
PPP5C 4025.0
H2BC17 4130.0
TDG 4222.0
MAD2L2 4234.0
FAN1 4238.0
XRCC2 4289.0
POLR2E 4421.0
PCLAF 4431.0
NEIL1 4459.0
RNF168 4485.0
INO80B 4630.0
EME1 4646.0
H2BC11 4657.0
RPA3 4736.0
TOPBP1 4738.0
SUMO3 5005.0
ERCC6 5141.0
RNF4 5160.0
CCNA2 5235.0
POLD1 5363.0
H4C5 5401.0
H2AZ2 5485.0
USP1 5490.0
RAD51C 5512.0
UBE2B 5554.0
XAB2 5683.0
GTF2H4 5821.0
TOP3A 5902.0
POLE3 5980.0
USP43 6007.0
PPP4C 6208.0
XRCC3 6301.0
EYA2 6365.0
H2AC6 6426.0
OGG1 6502.0
TCEA1 6529.0
RAD50 6618.0
ERCC4 6718.0
H2AX 6737.0
PARP1 6975.0
RPA1 7064.0
KPNA2 7126.0
CLSPN 7366.0
GPS1 7505.0
FANCI 7545.0
APBB1 7865.0
POLR2D 8105.0
MUTYH 8107.0
POLM 8209.0
POLN 8973.0
POLR2J 10234.0



REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53
591
set REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53
setSize 351
pANOVA 7.29e-09
s.dist -0.18
p.adjustANOVA 5.99e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
NLRC4 -10566
PIP4K2C -10542
POLR2C -10372
RMI2 -10267
ERCC3 -10242
KAT6A -10229
CASP10 -10209
YWHAG -10207
SESN3 -10179
AGO4 -9949
CSNK2A1 -9812
EP300 -9776
CCNE2 -9681
BLM -9563
UBC -9558
NBN -9502
CNOT10 -9481
CCNG1 -9440
TP53BP2 -9416
CDC25C -9256

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NLRC4 -10566
PIP4K2C -10542
POLR2C -10372
RMI2 -10267
ERCC3 -10242
KAT6A -10229
CASP10 -10209
YWHAG -10207
SESN3 -10179
AGO4 -9949
CSNK2A1 -9812
EP300 -9776
CCNE2 -9681
BLM -9563
UBC -9558
NBN -9502
CNOT10 -9481
CCNG1 -9440
TP53BP2 -9416
CDC25C -9256
CHEK1 -9151
RAD51D -9148
TXN -9118
ARID3A -9109
KMT5A -9054
GADD45A -9000
SGK1 -8979
DDB2 -8878
HUS1 -8871
CASP1 -8859
CSNK2A2 -8850
TP53RK -8826
CASP6 -8753
SESN2 -8751
GATAD2B -8745
CASP2 -8729
MLST8 -8569
TFDP2 -8530
COX20 -8517
IGFBP3 -8436
MAP2K6 -8430
PIP4P1 -8351
CNOT8 -8208
RBL1 -8170
TFDP1 -8155
RAD1 -8063
ZNF420 -8057
NDRG1 -8051
CDK2 -8046
TAF12 -8042
PHF20 -8020
SUPT4H1 -7958
PCNA -7849
CNOT6L -7826
RRM2B -7813
PMS2 -7786
CDKN2A -7757
BBC3 -7702
POLR2K -7697
PRMT1 -7681
AGO3 -7679
TNRC6B -7491
ATRIP -7316
POLR2A -7267
CDK9 -7238
POU4F1 -6814
PML -6800
CDKN1B -6757
COX19 -6756
TP53I3 -6677
COX7A2L -6623
GSR -6596
SCO1 -6569
COX6A1 -6563
TAF15 -6543
GTF2F1 -6537
PRKAA1 -6472
HIPK1 -6449
COX4I1 -6386
SCO2 -6325
YWHAH -6318
AIFM2 -6303
MAPKAPK5 -6287
PIP4K2A -6189
YWHAZ -6164
TP53INP1 -6127
COX7C -6123
CCNH -6119
AGO1 -6050
CRADD -5985
TACO1 -5949
MBD3 -5903
GPX2 -5878
AURKA -5849
POU4F2 -5822
PRR5 -5818
BARD1 -5779
PRELID1 -5708
PTEN -5677
MRE11 -5675
E2F8 -5629
ATM -5608
RBBP8 -5574
HDAC2 -5534
TIGAR -5488
TMEM219 -5410
RFFL -5368
TNFRSF10B -5251
CHEK2 -5211
CDK13 -5194
TAF4B -5149
FAS -5132
BCL6 -5121
SSRP1 -5110
KAT5 -5079
RICTOR -5024
L3MBTL1 -5021
CDKN1A -5005
PLAGL1 -4952
ATR -4921
ELOC -4748
MEAF6 -4676
LAMTOR2 -4633
MOV10 -4504
NDUFA4 -4469
NELFB -4457
TNRC6C -4438
MAPK14 -4437
COX14 -4397
AKT1 -4393
PRKAB1 -4382
GTF2H5 -4378
TAF7 -4369
LAMTOR3 -4343
TRIAP1 -4326
TXNRD1 -4302
TNFRSF10C -4290
TBP -4230
PLK2 -4154
ELL -4130
CTDP1 -4083
SURF1 -4018
GPI -3859
RFC5 -3853
PRDX5 -3772
BRD7 -3663
NOC2L -3651
GTF2H1 -3642
AKT3 -3595
CNOT7 -3535
CYCS -3407
PIN1 -3401
JMY -3352
SESN1 -3275
BRPF3 -3268
MNAT1 -3244
TAF2 -3194
CNOT1 -3172
TAF9 -3142
PMAIP1 -3107
SMYD2 -3103
EHMT2 -3061
MTA2 -2984
E2F4 -2971
MAPKAP1 -2964
POLR2I -2893
ING2 -2880
RFC4 -2868
AURKB -2861
RFC3 -2823
APAF1 -2771
CDK1 -2730
CCNA1 -2724
SUPT16H -2715
CNOT2 -2651
POLR2B -2615
GTF2H3 -2584
COX16 -2510
PPP2CB -2471
GATAD2A -2405
PRDX2 -2230
LAMTOR1 -2197
ELOA2 -2193
CSNK2B -2185
DYRK2 -2168
RAD17 -2076
FANCC -1907
BID -1872
COX6C -1852
LRPPRC -1749
RRAGA -1665
TTC5 -1646
HIPK2 -1566
EXO1 -1398
PRKAG1 -1371
CNOT4 -1314
LAMTOR4 -1274
POLR2G -1251
CNOT6 -1230
PRKAA2 -1220
CCNE1 -1118
RMI1 -1101
EHMT1 -1095
MDM2 -1085
RHNO1 -1080
TNKS1BP1 -1066
RAD9B -1016
COX6B1 -915
BAX -888
TP53 -831
TAF3 -770
SLC38A9 -700
USP2 -680
RRAGD -670
RAD9A -486
COX18 -423
MLH1 -367
PCBP4 -174
TSC1 -111
PRKAG2 -89
MDM4 -86
TNFRSF10A -44
RBBP4 -33
YWHAQ -11
PRDX1 13
DDIT4 61
COX11 91
CHD3 338
PPP2R5C 395
BRCA1 456
PRMT5 482
RABGGTA 515
GTF2F2 536
BNIP3L 557
PRELID3A 588
FOS 612
BANP 616
GLS 658
ING5 674
TAF13 758
CDK12 819
ATF2 857
CNOT9 886
ELOB 914
YWHAE 1068
PDPK1 1090
E2F7 1096
DAXX 1201
MDC1 1223
UBB 1320
WRN 1553
RPA2 1570
CCNT2 1685
SUPT5H 1775
YWHAB 1797
FANCD2 1800
TAF1L 1828
CDK7 1850
POLR2L 1891
TNRC6A 1957
LAMTOR5 1974
PPP2R1B 2037
SETD9 2053
AGO2 2114
PRDM1 2166
TPX2 2214
BRD1 2222
NPM1 2295
RPS27A 2313
ERCC2 2323
USP7 2400
CENPJ 2408
STK11 2424
COX5B 2447
CNOT11 2470
TP63 2558
BRIP1 2607
PPP2CA 2625
UBA52 2643
PLK3 2742
NELFCD 2763
DNA2 2831
NELFE 2912
RFC2 2936
JUN 3045
POLR2H 3091
BCL2L14 3255
RABGGTB 3261
PPP1R13L 3311
CCNB1 3317
PERP 3332
ZNF385A 3333
RPTOR 3371
TAF10 3510
CCNK 3604
NELFA 3698
POLR2F 3701
CNOT3 3705
MSH2 3713
RNF34 3727
PPP1R13B 3749
ELOA 3804
TAF5 3845
PIP4K2B 3878
RBL2 3958
COX5A 4199
RHEB 4307
BTG2 4411
POLR2E 4421
TP73 4436
RPA3 4736
TOPBP1 4738
TSC2 4893
HDAC1 4949
TAF11 4988
PIDD1 5138
CCNA2 5235
PRKAB2 5499
TAF4 5622
RGCC 5680
CREBBP 5734
GTF2H4 5821
AKT2 5824
TOP3A 5902
MTOR 6030
COX8A 6060
PPP2R1A 6221
CHD4 6248
NUAK1 6275
RRAGC 6521
TCEA1 6529
RAD50 6618
GLS2 6706
BRPF1 6984
RPA1 7064
E2F1 7131
CCNT1 7156
TNFRSF10D 7174
BIRC5 7359
FANCI 7545
CARM1 7764
TAF6 7963
POLR2D 8105
MAPK11 8999
CDK5 9357
PRKAG3 9785
CDK5R1 10081
SFN 10169
POLR2J 10234
STEAP3 10470
TP53AIP1 10590



REACTOME_VESICLE_MEDIATED_TRANSPORT

REACTOME_VESICLE_MEDIATED_TRANSPORT
934
set REACTOME_VESICLE_MEDIATED_TRANSPORT
setSize 642
pANOVA 1.22e-08
s.dist -0.132
p.adjustANOVA 9.58e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
AREG -10981
HP -10960
APOL1 -10957
AVP -10848
RABGAP1 -10670
TOR1A -10657
SCARF1 -10598
GRK2 -10571
CALR -10512
CTSZ -10474
MON1A -10422
TRAPPC3 -10403
ANKRD28 -10373
EPGN -10353
TUBA3D -10346
CLINT1 -10326
TRAPPC10 -10290
TBC1D2 -10252
DCTN2 -10239
CD59 -10212

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AREG -10981
HP -10960
APOL1 -10957
AVP -10848
RABGAP1 -10670
TOR1A -10657
SCARF1 -10598
GRK2 -10571
CALR -10512
CTSZ -10474
MON1A -10422
TRAPPC3 -10403
ANKRD28 -10373
EPGN -10353
TUBA3D -10346
CLINT1 -10326
TRAPPC10 -10290
TBC1D2 -10252
DCTN2 -10239
CD59 -10212
YWHAG -10207
HPS4 -10201
ARRB1 -10157
TUBB4B -10078
RACGAP1 -10072
TMED2 -9959
PACSIN2 -9948
RIN3 -9932
SLC18A3 -9904
BLOC1S1 -9891
SCARB2 -9884
RAB13 -9859
COPS5 -9794
AP4S1 -9725
HPR -9698
PICALM -9587
UBC -9558
RAC1 -9520
EREG -9500
DYNLL1 -9489
WASL -9476
COPS7A -9475
STX10 -9463
DYNC1LI1 -9445
STX5 -9365
SORT1 -9356
NECAP1 -9248
NAPA -9160
ARF3 -9134
COPS2 -9132
HSPA8 -9110
RAB3A -9107
TMED10 -9047
TRAPPC6B -9014
RAB18 -8986
ARF1 -8984
RAB8A -8934
GOSR1 -8917
TBC1D13 -8907
VPS53 -8892
VAMP8 -8876
KIF27 -8869
DENND3 -8865
KIFC2 -8844
MIA2 -8834
SEC24A -8812
TUBB4A -8809
BIN1 -8738
CHMP4A -8725
RAB14 -8674
ANKRD27 -8671
GABARAP -8629
GOLGB1 -8626
MARCO -8597
TMF1 -8581
KIFAP3 -8551
GAPVD1 -8548
TGFA -8513
VPS54 -8501
DNM3 -8428
GJA1 -8427
FTH1 -8414
KIF21B -8413
GCC1 -8409
CALM1 -8399
TBC1D10A -8371
RAB32 -8213
VPS37C -8205
PIP5K1C -8088
SNX18 -8026
TMED3 -8012
GJA9 -7934
AP1S1 -7907
FCHO1 -7899
TMED7 -7896
STAM -7881
COPS3 -7856
ARF6 -7839
KIF2C -7797
KIF21A -7737
TBC1D15 -7728
CHRM2 -7713
EPS15 -7704
COPB2 -7633
RAB27B -7537
SURF4 -7475
CBL -7394
COG3 -7385
CHMP2B -7324
SYNJ1 -7301
VAMP4 -7290
KDELR1 -7280
NECAP2 -7276
SAR1B -7270
DENND1B -7256
CYTH4 -7250
GORASP1 -7243
DNM2 -7164
RHOBTB3 -7136
GALNT1 -7079
LNPEP -7076
FNBP1 -7052
OPTN -7047
COPS4 -6973
HYOU1 -6918
SEC24D -6903
MAP1LC3B -6900
TSG101 -6877
TUBAL3 -6859
COG1 -6840
STXBP3 -6828
TUBA4A -6826
SNAP23 -6823
NAPG -6808
KIF5B -6805
AP1M2 -6763
RINT1 -6701
CPD -6684
HBA2 -6670
FTL -6608
COPG1 -6605
DYNC1I2 -6523
TBC1D7 -6499
TUBB3 -6481
RAB27A -6480
HBEGF -6448
TUBA4B -6407
YWHAH -6318
TPD52 -6284
STX17 -6260
VPS51 -6240
DENND5A -6234
MAN2A1 -6229
TRAPPC13 -6218
KIF13B -6178
YWHAZ -6164
RAB3GAP2 -6160
VPS36 -6155
RALGAPA2 -6147
KIF2B -6144
SEC13 -6136
RAB31 -6084
ACTR1A -6083
TUBA1A -6069
LDLR -6061
RAB10 -5924
SEC23A -5922
ACBD3 -5816
TOR1B -5738
PAFAH1B1 -5709
ITSN2 -5658
ACTR2 -5655
SEC22A -5585
RAB1A -5565
CLTA -5506
APP -5475
SEC31A -5444
COPA -5440
GBF1 -5436
AGFG1 -5414
TUBB2A -5397
TFG -5371
USP6NL -5348
TBC1D14 -5306
APOA1 -5268
DCTN6 -5234
COPS6 -5228
VPS28 -5222
DENND4A -5198
RAB36 -5196
ARFIP2 -5191
AP3B1 -5145
RAB7A -5134
AP2M1 -5107
NBAS -5104
ARRB2 -5102
CHMP6 -5085
RAB1B -5084
ACTG1 -5045
EXOC5 -5006
CNIH1 -5002
PLA2G6 -4913
ANK3 -4879
CUX1 -4878
AP4B1 -4860
PAFAH1B3 -4857
RAB38 -4844
KIF16B -4819
GGA3 -4794
VPS37A -4694
ARFGAP3 -4646
MAN1A1 -4644
ULK1 -4639
RAB8B -4595
BLOC1S4 -4591
TUBB6 -4561
AKT1 -4393
PRKAB1 -4382
FOLR1 -4374
PIK3C2A -4361
DENND4B -4352
VPS4B -4332
DYNC1H1 -4301
SNAPIN -4284
KDELR3 -4232
HPS1 -4185
GRB2 -4184
AP2B1 -4081
F5 -4071
EXOC6 -4062
RAB43 -4050
SNX5 -4046
GOLGA4 -4043
SYTL1 -4001
TJP1 -3989
ALPP -3948
AP1G2 -3903
TBC1D1 -3877
CHMP2A -3860
EPN1 -3834
KDELR2 -3830
DENND4C -3811
SH3GL2 -3804
GOLGA2 -3802
RALGAPB -3800
AP2A1 -3781
HIP1 -3760
AGTR1 -3742
TRAPPC6A -3667
MVB12A -3624
AAK1 -3619
NAPB -3603
AKT3 -3595
SEC24C -3587
ARPC3 -3530
KIF22 -3529
LMAN1 -3525
SYNJ2 -3524
GJD3 -3523
VTA1 -3517
DENND6A -3511
DENND1A -3503
LMAN2L -3494
KIF18A -3490
IGF2R -3375
COPB1 -3302
DCTN4 -3208
KIF1B -3198
GJB2 -3190
TUBA1C -3186
SYS1 -3166
VAMP2 -3158
KIF20B -3126
SPTBN1 -3118
UBAP1 -3098
AP1M1 -3083
KIAA0319 -2961
COPS8 -2952
ARFRP1 -2934
CLTC -2915
GJD4 -2904
VAMP3 -2881
TRAPPC5 -2822
COG4 -2801
NAA38 -2797
RAB5B -2791
EXOC7 -2772
COPS7B -2697
GNS -2689
MON1B -2688
KIF3B -2685
CAPZA2 -2683
AP1B1 -2672
REPS1 -2635
USO1 -2632
KIF11 -2597
KIF9 -2570
RAB33B -2551
TUBA8 -2524
APOB -2485
NAA30 -2465
MADD -2448
HBA1 -2430
BICD1 -2421
ARPC5 -2287
ACTR3 -2275
HSP90AA1 -2213
SPTAN1 -2199
CHMP4C -2173
DYNC1I1 -2149
COG7 -2146
CENPE -2121
TUBB2B -2109
GJA10 -2064
SEC23IP -2026
DCTN1 -2023
CHMP3 -2000
CYTH2 -1979
PREB -1919
COLEC12 -1905
AP4E1 -1880
DNASE2 -1867
STX4 -1845
MAN2A2 -1835
KLC1 -1763
GCC2 -1727
KIF23 -1597
EXOC8 -1583
CSNK1D -1577
SNX2 -1574
TXNDC5 -1573
CAPZB -1568
TBC1D10B -1505
TRAPPC11 -1484
RABGEF1 -1475
CAPZA1 -1452
HSP90B1 -1447
GABARAPL2 -1438
TBC1D24 -1409
SCOC -1406
M6PR -1405
RAB11A -1382
PPP6C -1377
PRKAG1 -1371
DAB2 -1356
ANK2 -1346
SEC22C -1249
PRKAA2 -1220
GDI2 -1214
GOSR2 -1204
SLC2A8 -1201
FNBP1L -1097
TRAPPC8 -1070
COL3A1 -1069
KIF20A -1025
VPS45 -1021
EXOC1 -1004
RAB6A -961
GALNT2 -837
PUM1 -762
CLVS1 -745
ASPSCR1 -718
TRIP10 -643
KLC2 -596
GJB6 -595
COPE -594
COG8 -544
ACTB -471
CYTH1 -433
SGIP1 -416
RIC1 -394
SEC22B -384
TUBA3C -374
SNAP91 -369
RALA -305
SYT11 -267
LMAN2 -232
FCHO2 -206
EPS15L1 -138
TSC1 -111
TRAPPC4 -98
TUBA3E -95
PRKAG2 -89
SEC24B -71
KLC3 -70
GJC2 -68
ARF4 -67
EXOC2 -46
SCFD1 -28
RABEP1 -27
SNF8 -25
MAN1C1 -20
YWHAQ -11
UBQLN1 23
AP1S3 26
MCFD2 29
GOLIM4 65
WNT5A 130
AMPH 154
NEDD8 160
TBC1D20 206
RAB39A 237
GAK 255
KLC4 269
STON2 297
BTC 301
RAB11B 392
RAB5A 398
PPP6R3 477
EXOC4 522
GGA1 545
TBC1D4 599
RAB5C 623
ARFGAP2 654
ALS2 667
PAFAH1B2 687
GJB7 694
CTTN 699
LRP2 713
YKT6 867
MSR1 881
CYTH3 890
PACSIN3 941
MYO6 943
COLEC11 966
SYT1 1000
MIA3 1018
COPZ1 1020
COPG2 1041
YWHAE 1068
DENND5B 1069
TFRC 1092
ARPC4 1111
SBF2 1140
COG2 1148
SNX9 1154
GGA2 1271
STAB1 1289
UBB 1320
KIF3A 1322
VTI1A 1349
SSC5D 1364
VPS37B 1367
ARPC2 1448
SLC2A4 1464
TRAPPC1 1479
VPS52 1625
CHMP5 1670
DENND2C 1711
STAM2 1734
GOLGA1 1753
YWHAB 1797
COG6 1816
CHMP7 1896
ARCN1 1940
RAB4A 1983
AP2A2 1989
AGPAT3 2031
DVL2 2093
CTSC 2104
SEC16A 2108
MYO1C 2134
RAB35 2139
KIF6 2159
LDLRAP1 2173
STX16 2272
RPS27A 2313
KIF25 2331
BET1L 2379
RINL 2386
GRK3 2443
AP4M1 2486
BET1 2489
KIF15 2519
CLVS2 2569
CD163 2571
COL4A1 2572
DYNC1LI2 2640
UBA52 2643
SPTBN4 2646
TMED9 2667
SCARB1 2726
STON1 2733
RAB21 2740
TBC1D17 2745
EGF 2787
TGOLN2 2791
EPN2 2799
SPTA1 2809
RAB3IP 2814
VPS4A 2877
COG5 2921
KIF3C 2942
VPS37D 2948
USE1 3028
DTNBP1 3403
ITSN1 3422
TBC1D10C 3455
ARF5 3512
MAN1A2 3574
KIFC1 3575
BLOC1S3 3582
SH3GL1 3638
MVB12B 3703
TACR1 3746
KIF2A 3843
BLOC1S6 3895
ALB 4005
GJD2 4051
DENND1C 4062
TPD52L1 4073
TRAPPC9 4079
COL1A2 4150
PPP6R1 4206
C2CD5 4209
RAB3GAP1 4296
GOLGA5 4319
AP3S1 4333
RIN2 4348
RAB30 4370
BICD2 4377
HSPH1 4401
MYH9 4460
NSF 4491
DNAJC6 4559
KIF1C 4589
TUBA1B 4671
TRAPPC12 4694
AP1G1 4721
CD55 4766
RAB3IL1 4779
ANK1 4865
TSC2 4893
SYT2 4900
HIP1R 4935
MYO5A 4951
STX18 4978
TRIP11 5034
TMEM115 5094
SYT9 5146
ADRB2 5167
GJC1 5324
CNIH2 5432
PLA2G4A 5443
PRKAB2 5499
DENND2D 5526
TUBB1 5561
PACSIN1 5596
SRC 5689
EGFR 5712
NAA35 5754
KIF19 5755
DCTN5 5779
AKT2 5824
APOE 5875
KIF26A 5920
CHMP4B 5954
RIN1 6102
GJA4 6157
ZW10 6165
TRAPPC2L 6188
DNM1 6255
GJA3 6260
STX6 6306
GJB3 6328
DENND2A 6348
CD36 6422
KIF4B 6448
SH3GL3 6459
ACTR10 6469
RHOQ 6485
LMAN1L 6508
KIF12 6570
TBC1D16 6593
HGS 6652
KIF26B 6735
ARPC1A 6795
SERPINA1 6864
AP2S1 6934
HPX 6937
EXOC3 6987
SCARA5 6991
CD4 7022
DENND2B 7047
BNIP1 7055
VPS25 7242
LRP1 7369
JCHAIN 7499
GPS1 7505
CAPZA3 7525
GJA5 7549
RAB12 7564
ARL1 7584
CNIH3 7590
COL4A2 7661
SH3D19 7665
SPTBN2 7669
KIF1A 7672
SPARC 7683
KIF18B 7685
DCTN3 7804
COPZ2 7836
RGP1 7882
SYT8 7896
SNAP29 7925
RABEPK 7999
CFTR 8023
KIF5A 8065
AMBP 8070
SCGB3A2 8101
CLTB 8332
CLTCL1 8339
GRIA1 8366
HBB 8442
SBF1 8494
TF 8567
GJB4 8736
COL1A1 8811
ARFGAP1 8891
SEC16B 8958
ALS2CL 8981
DYNLL2 9125
RAB6B 9169
GJA8 9188
FZD4 9228
COL7A1 9254
INS 9345
SPTBN5 9424
SPTB 9535
MASP1 9581
STAB2 9627
CHML 9779
PRKAG3 9785
PLIN3 9954
SFN 10169
IL7R 10351
DENND6B 10370
GJB5 10758
TUBB8 10871
SAA1 10902
CD3G 10960
CD3D 10994



REACTOME_ESR_MEDIATED_SIGNALING

REACTOME_ESR_MEDIATED_SIGNALING
1281
set REACTOME_ESR_MEDIATED_SIGNALING
setSize 210
pANOVA 1.53e-08
s.dist -0.226
p.adjustANOVA 1.14e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
AREG -10981
CTSD -10727
H2BC6 -10708
H3C6 -10650
CXXC5 -10585
FKBP5 -10424
POLR2C -10372
EPGN -10353
MYB -10255
GNB5 -10046
SHC1 -10031
AGO4 -9949
H4C3 -9942
EP300 -9776
H2BC12 -9581
EREG -9500
H4C11 -9492
H4C9 -9486
PIK3R1 -9422
RUNX1 -9414

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AREG -10981.0
CTSD -10727.0
H2BC6 -10708.0
H3C6 -10650.0
CXXC5 -10585.0
FKBP5 -10424.0
POLR2C -10372.0
EPGN -10353.0
MYB -10255.0
GNB5 -10046.0
SHC1 -10031.0
AGO4 -9949.0
H4C3 -9942.0
EP300 -9776.0
H2BC12 -9581.0
EREG -9500.0
H4C11 -9492.0
H4C9 -9486.0
PIK3R1 -9422.0
RUNX1 -9414.0
H2BC5 -9371.0
NRIP1 -9352.0
H3-3A -9260.0
H4C16 -9179.0
H2AC4 -9092.0
GATA3 -9064.0
KRAS -8798.0
MAPK1 -8617.0
MED1 -8570.0
TGFA -8513.0
H2BC1 -8504.0
KAT2B -8472.0
H4C13 -8401.0
CALM1 -8399.0
H3-3B -8363.0
AXIN1 -8331.0
GTF2A2 -8284.0
H3C8 -8260.0
H2BC3 -8237.0
H2BC8 -8108.0
NRAS -7996.0
NCOA2 -7957.0
UHMK1 -7844.0
HSP90AB1 -7735.0
POLR2K -7697.0
H3C11 -7686.0
PRMT1 -7681.0
AGO3 -7679.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
TNRC6B -7491.0
FOSB -7478.0
GNB2 -7436.0
H2AJ -7338.0
FOXA1 -7309.0
POLR2A -7267.0
CDK9 -7238.0
H2BC10 -6977.0
USF2 -6961.0
FOXO3 -6952.0
H3C3 -6933.0
CBFB -6875.0
H3C12 -6825.0
CDKN1B -6757.0
H2AC8 -6733.0
GNG3 -6698.0
GNGT1 -6589.0
GTF2F1 -6537.0
H2AC18 -6516.5
H2AC19 -6516.5
GNG10 -6483.0
HBEGF -6448.0
GNAI3 -6294.0
CHD1 -6270.0
H2BC14 -6126.0
AGO1 -6050.0
SP1 -5960.0
PTGES3 -5864.0
POU2F1 -5859.0
HSPB1 -5590.0
H3C2 -5478.0
PIK3CA -5472.0
H2AC7 -5340.5
H2BC7 -5340.5
GNG11 -5292.0
YY1 -5148.0
KAT5 -5079.0
KDM4B -4912.0
STRN -4804.0
GPAM -4680.0
XPO1 -4530.0
MOV10 -4504.0
TNRC6C -4438.0
AKT1 -4393.0
GTF2A1 -4237.0
TBP -4230.0
PIK3R2 -4094.0
H4C4 -4007.0
GNG7 -3819.0
H2BC21 -3732.0
NCOA1 -3650.0
AKT3 -3595.0
H4C6 -3568.0
GNAI2 -3527.0
GNB1 -3520.0
H2AC14 -3377.0
ESR2 -3312.0
STAG1 -3119.0
H3C4 -3045.0
POLR2I -2893.0
GNB4 -2618.0
POLR2B -2615.0
KANK1 -2443.0
GNG12 -2359.0
NCOA3 -2235.0
HSP90AA1 -2213.0
GNG5 -2179.0
CAV2 -2091.0
MYC -2072.0
SRF -1998.0
NOS3 -1936.0
USF1 -1841.0
RAD21 -1610.0
JUND -1598.0
SMC3 -1334.0
POLR2G -1251.0
H3C10 -1128.0
HRAS -1109.0
H4C12 -1092.0
KDM1A -970.0
H4C2 -859.0
NR5A2 -826.0
SPHK1 -631.0
TLE3 -422.0
PRKCZ -386.0
GNG8 -148.0
H2BC13 1.0
CXCL12 64.0
ZDHHC7 133.0
ERBB4 296.0
BTC 301.0
GTF2F2 536.0
BCL2 594.0
FOS 612.0
ATF2 857.0
PDPK1 1090.0
CCND1 1122.0
CAV1 1218.0
MMP9 1241.0
H4C8 1444.0
GNG2 1545.0
H2BC26 1619.0
MMP2 1631.0
POLR2L 1891.0
S1PR3 1911.0
TNRC6A 1957.0
AGO2 2114.0
H2BC15 2203.0
CREB1 2212.0
KCTD6 2338.0
H2BC4 2363.0
H4C1 2583.0
EGF 2787.0
EBAG9 2836.0
PPID 2905.0
JUN 3045.0
POLR2H 3091.0
H2AC20 3179.0
PGR 3276.0
FKBP4 3431.0
GNAI1 3557.0
POLR2F 3701.0
PTK2 3709.0
PPP5C 4025.0
H2BC17 4130.0
POLR2E 4421.0
DDX5 4449.0
H2BC11 4657.0
H3C1 4735.0
ESR1 4769.0
HDAC1 4949.0
GNAT3 5218.0
GNG4 5224.0
IGF1R 5272.0
H4C5 5401.0
H2AZ2 5485.0
MMP7 5597.0
SRC 5689.0
EGFR 5712.0
CREBBP 5734.0
AKT2 5824.0
H2AC6 6426.0
ZDHHC21 6460.0
H2AX 6737.0
ZNF217 6859.0
KPNA2 7126.0
PIK3R3 7144.0
CCNT1 7156.0
GREB1 7739.0
CARM1 7764.0
MAPK3 7947.0
GNG13 8027.0
POLR2D 8105.0
GNB3 9683.0
MMP3 9780.0
TFF1 10134.0
POLR2J 10234.0
TFF3 10295.0
GNGT2 10884.0



REACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

REACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION
1395
set REACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION
setSize 140
pANOVA 3.97e-08
s.dist -0.269
p.adjustANOVA 2.83e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
CTSD -10727
H2BC6 -10708
H3C6 -10650
CXXC5 -10585
POLR2C -10372
MYB -10255
AGO4 -9949
H4C3 -9942
EP300 -9776
H2BC12 -9581
H4C11 -9492
H4C9 -9486
RUNX1 -9414
H2BC5 -9371
NRIP1 -9352
H3-3A -9260
H4C16 -9179
H2AC4 -9092
GATA3 -9064
MED1 -8570

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CTSD -10727.0
H2BC6 -10708.0
H3C6 -10650.0
CXXC5 -10585.0
POLR2C -10372.0
MYB -10255.0
AGO4 -9949.0
H4C3 -9942.0
EP300 -9776.0
H2BC12 -9581.0
H4C11 -9492.0
H4C9 -9486.0
RUNX1 -9414.0
H2BC5 -9371.0
NRIP1 -9352.0
H3-3A -9260.0
H4C16 -9179.0
H2AC4 -9092.0
GATA3 -9064.0
MED1 -8570.0
TGFA -8513.0
H2BC1 -8504.0
KAT2B -8472.0
H4C13 -8401.0
H3-3B -8363.0
AXIN1 -8331.0
GTF2A2 -8284.0
H3C8 -8260.0
H2BC3 -8237.0
H2BC8 -8108.0
NCOA2 -7957.0
HSP90AB1 -7735.0
POLR2K -7697.0
H3C11 -7686.0
PRMT1 -7681.0
AGO3 -7679.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
TNRC6B -7491.0
FOSB -7478.0
H2AJ -7338.0
FOXA1 -7309.0
POLR2A -7267.0
CDK9 -7238.0
H2BC10 -6977.0
USF2 -6961.0
H3C3 -6933.0
CBFB -6875.0
H3C12 -6825.0
H2AC8 -6733.0
GTF2F1 -6537.0
H2AC18 -6516.5
H2AC19 -6516.5
CHD1 -6270.0
H2BC14 -6126.0
AGO1 -6050.0
SP1 -5960.0
PTGES3 -5864.0
POU2F1 -5859.0
H3C2 -5478.0
H2AC7 -5340.5
H2BC7 -5340.5
YY1 -5148.0
KAT5 -5079.0
KDM4B -4912.0
GPAM -4680.0
MOV10 -4504.0
TNRC6C -4438.0
GTF2A1 -4237.0
TBP -4230.0
H4C4 -4007.0
H2BC21 -3732.0
NCOA1 -3650.0
H4C6 -3568.0
H2AC14 -3377.0
STAG1 -3119.0
H3C4 -3045.0
POLR2I -2893.0
POLR2B -2615.0
KANK1 -2443.0
NCOA3 -2235.0
HSP90AA1 -2213.0
MYC -2072.0
USF1 -1841.0
RAD21 -1610.0
JUND -1598.0
SMC3 -1334.0
POLR2G -1251.0
H3C10 -1128.0
H4C12 -1092.0
KDM1A -970.0
H4C2 -859.0
NR5A2 -826.0
TLE3 -422.0
H2BC13 1.0
CXCL12 64.0
ERBB4 296.0
GTF2F2 536.0
BCL2 594.0
FOS 612.0
ATF2 857.0
CCND1 1122.0
H4C8 1444.0
H2BC26 1619.0
POLR2L 1891.0
TNRC6A 1957.0
AGO2 2114.0
H2BC15 2203.0
KCTD6 2338.0
H2BC4 2363.0
H4C1 2583.0
EBAG9 2836.0
JUN 3045.0
POLR2H 3091.0
H2AC20 3179.0
PGR 3276.0
FKBP4 3431.0
POLR2F 3701.0
H2BC17 4130.0
POLR2E 4421.0
DDX5 4449.0
H2BC11 4657.0
H3C1 4735.0
ESR1 4769.0
HDAC1 4949.0
H4C5 5401.0
H2AZ2 5485.0
CREBBP 5734.0
H2AC6 6426.0
H2AX 6737.0
ZNF217 6859.0
KPNA2 7126.0
CCNT1 7156.0
GREB1 7739.0
CARM1 7764.0
POLR2D 8105.0
TFF1 10134.0
POLR2J 10234.0
TFF3 10295.0



REACTOME_RHO_GTPASE_EFFECTORS

REACTOME_RHO_GTPASE_EFFECTORS
342
set REACTOME_RHO_GTPASE_EFFECTORS
setSize 305
pANOVA 4.28e-08
s.dist -0.182
p.adjustANOVA 2.87e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A8 -10967
H2BC6 -10708
H3C6 -10650
RHOG -10627
LIMK2 -10612
S100A9 -10359
TUBA3D -10346
PRKCD -10313
YWHAG -10207
CDC42 -10147
TUBB4B -10078
H4C3 -9942
LIMK1 -9824
H2BC12 -9581
IQGAP2 -9572
PIK3C3 -9526
RAC1 -9520
H4C11 -9492
DYNLL1 -9489
H4C9 -9486

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A8 -10967.0
H2BC6 -10708.0
H3C6 -10650.0
RHOG -10627.0
LIMK2 -10612.0
S100A9 -10359.0
TUBA3D -10346.0
PRKCD -10313.0
YWHAG -10207.0
CDC42 -10147.0
TUBB4B -10078.0
H4C3 -9942.0
LIMK1 -9824.0
H2BC12 -9581.0
IQGAP2 -9572.0
PIK3C3 -9526.0
RAC1 -9520.0
H4C11 -9492.0
DYNLL1 -9489.0
H4C9 -9486.0
WASL -9476.0
DYNC1LI1 -9445.0
TAX1BP3 -9427.0
H2BC5 -9371.0
PFN1 -9274.0
H3-3A -9260.0
CDC25C -9256.0
NCKAP1L -9254.0
H4C16 -9179.0
H2AC4 -9092.0
CLIP1 -8978.0
TUBB4A -8809.0
CENPA -8800.0
MAPK1 -8617.0
MYL12B -8541.0
H2BC1 -8504.0
PPP2R5B -8503.0
H4C13 -8401.0
CALM1 -8399.0
H3-3B -8363.0
WASF2 -8328.0
NSL1 -8302.0
H3C8 -8260.0
H2BC3 -8237.0
CENPQ -8231.0
PPP1R14A -8110.0
H2BC8 -8108.0
NCOA2 -7957.0
NDE1 -7893.0
KIF2C -7797.0
ZWINT -7770.0
NUDC -7747.0
H3C11 -7686.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
NCF2 -7461.0
WIPF1 -7342.0
H2AJ -7338.0
ZWILCH -7287.0
KIF14 -7015.0
H2BC10 -6977.0
BUB1B -6938.0
H3C3 -6933.0
TUBAL3 -6859.0
TUBA4A -6826.0
H3C12 -6825.0
BRK1 -6818.0
KIF5B -6805.0
CDKN1B -6757.0
H2AC8 -6733.0
DYNC1I2 -6523.0
H2AC18 -6516.5
H2AC19 -6516.5
TUBB3 -6481.0
TUBA4B -6407.0
CLASP2 -6389.0
YWHAH -6318.0
SPC24 -6225.0
YWHAZ -6164.0
KIF2B -6144.0
SEC13 -6136.0
H2BC14 -6126.0
TUBA1A -6069.0
KDM4C -6032.0
ROCK2 -5794.0
PAFAH1B1 -5709.0
ITGB3BP -5665.0
ACTR2 -5655.0
H3C2 -5478.0
RHOA -5450.0
FMNL1 -5405.0
TUBB2A -5397.0
ROCK1 -5392.0
SKA1 -5357.0
H2AC7 -5340.5
H2BC7 -5340.5
TAOK1 -5276.0
MYL6 -5096.0
NDC80 -5070.0
ACTG1 -5045.0
SGO2 -4989.0
CENPC -4957.0
CFL1 -4824.0
KNL1 -4647.0
TUBB6 -4561.0
PPP1R12A -4556.0
XPO1 -4530.0
MAPK14 -4437.0
SCAI -4419.0
DYNC1H1 -4301.0
CENPP -4279.0
GRB2 -4184.0
PKN3 -4151.0
RCC2 -4121.0
CENPT -4073.0
H4C4 -4007.0
NUP133 -3990.0
ITGB1 -3970.0
NDEL1 -3912.0
CENPO -3864.0
CKAP5 -3856.0
CIT -3779.0
H2BC21 -3732.0
DIAPH1 -3654.0
PPP2R5E -3635.0
H4C6 -3568.0
RHPN1 -3533.0
ARPC3 -3530.0
KIF18A -3490.0
RPS27 -3484.0
PIN1 -3401.0
H2AC14 -3377.0
ABI2 -3209.0
PRKCB -3201.0
TUBA1C -3186.0
DSN1 -3120.0
H3C4 -3045.0
NCK1 -2917.0
ARPC1B -2913.0
MRTFA -2901.0
AURKB -2861.0
SGO1 -2709.0
NUP98 -2703.0
PPP1R12B -2698.0
CENPL -2691.0
NCF4 -2678.0
PMF1 -2655.0
NCKAP1 -2620.0
CLASP1 -2556.0
PIK3R4 -2533.0
TUBA8 -2524.0
NUP160 -2508.0
INCENP -2499.0
PPP2CB -2471.0
ARPC5 -2287.0
ACTR3 -2275.0
SPC25 -2166.0
DYNC1I1 -2149.0
CENPE -2121.0
AHCTF1 -2112.0
TUBB2B -2109.0
SRF -1998.0
B9D2 -1934.0
IQGAP3 -1902.0
DVL1 -1797.0
KLC1 -1763.0
NOX3 -1746.0
MYH14 -1698.0
PLK1 -1530.0
LIN7B -1485.0
PKN1 -1423.0
PPP2R5D -1303.0
PRC1 -1191.0
KTN1 -1164.0
DLG4 -1151.0
H3C10 -1128.0
H4C12 -1092.0
KDM1A -970.0
DIAPH3 -963.0
RAC2 -876.0
PAK1 -872.0
H4C2 -859.0
NUP37 -825.0
CENPN -774.0
CENPM -681.0
RANGAP1 -663.0
MEN1 -632.0
KLC2 -596.0
MIS12 -582.0
MYH10 -569.0
ABL1 -558.0
NUP43 -528.0
ACTB -471.0
PRKCZ -386.0
TUBA3C -374.0
MAD1L1 -288.0
NF2 -142.0
RTKN -104.0
TUBA3E -95.0
KLC3 -70.0
YWHAQ -11.0
H2BC13 1.0
BUB1 3.0
CTNNA1 39.0
PAK2 116.0
IQGAP1 143.0
CYBA 145.0
KLC4 269.0
WIPF3 290.0
NUP85 327.0
PPP2R5C 395.0
PPP1CC 455.0
CENPH 476.0
RHOD 551.0
PKN2 568.0
CTTN 699.0
BUB3 813.0
YWHAE 1068.0
PDPK1 1090.0
ARPC4 1111.0
NCKIPSD 1183.0
RANBP2 1258.0
NUF2 1321.0
MAPRE1 1433.0
H4C8 1444.0
ARPC2 1448.0
DAAM1 1580.0
CDH1 1603.0
H2BC26 1619.0
RHOC 1710.0
YWHAB 1797.0
MYH11 1902.0
PPP2R5A 1963.0
PPP2R1B 2037.0
DVL2 2093.0
H2BC15 2203.0
CTNNB1 2329.0
NUP107 2333.0
SKA2 2357.0
H2BC4 2363.0
H4C1 2583.0
PPP2CA 2625.0
DYNC1LI2 2640.0
CENPS 2903.0
CDC20 2914.0
PRKCA 3022.0
WASF1 3177.0
H2AC20 3179.0
CYFIP2 3267.0
KLK2 3394.0
PTK2 3709.0
CENPU 3842.0
KIF2A 3843.0
SPDL1 3844.0
KNTC1 3867.0
PFN2 3948.0
EVL 3986.0
CENPF 4067.0
H2BC17 4130.0
FMNL2 4308.0
MYH9 4460.0
NOXA1 4615.0
H2BC11 4657.0
TUBA1B 4671.0
H3C1 4735.0
PPP1CB 4911.0
ABI1 5365.0
H4C5 5401.0
H2AZ2 5485.0
TUBB1 5561.0
SRC 5689.0
RHPN2 5987.0
RHOB 6006.0
ZW10 6165.0
PPP2R1A 6221.0
H2AC6 6426.0
RHOQ 6485.0
GOPC 6551.0
H2AX 6737.0
BAIAP2 6744.0
DVL3 6786.0
ARPC1A 6795.0
SRGAP2 6977.0
WASF3 7143.0
MAD2L1 7226.0
CDCA8 7291.0
CENPK 7336.0
BIRC5 7359.0
CYFIP1 7726.0
MAPK3 7947.0
CFTR 8023.0
KIF5A 8065.0
NOXO1 8200.0
FMNL3 8342.0
MYLK 8421.0
SEH1L 8440.0
WIPF2 8508.0
MAPK11 8999.0
DYNLL2 9125.0
KLK3 9821.0
MYL9 9962.0
SFN 10169.0
TUBB8 10871.0
ROPN1 10918.0



REACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION

REACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION
1279
set REACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION
setSize 90
pANOVA 4.37e-08
s.dist -0.334
p.adjustANOVA 2.87e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
NFE2 -10939
MIR27A -10861
H2BC6 -10708
H3C6 -10650
GP1BA -10230
AGO4 -9949
H4C3 -9942
EP300 -9776
H2BC12 -9581
H4C11 -9492
H4C9 -9486
RUNX1 -9414
RBBP5 -9393
H2BC5 -9371
H3-3A -9260
H4C16 -9179
H2AC4 -9092
H2BC1 -8504
KAT2B -8472
H4C13 -8401

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NFE2 -10939.0
MIR27A -10861.0
H2BC6 -10708.0
H3C6 -10650.0
GP1BA -10230.0
AGO4 -9949.0
H4C3 -9942.0
EP300 -9776.0
H2BC12 -9581.0
H4C11 -9492.0
H4C9 -9486.0
RUNX1 -9414.0
RBBP5 -9393.0
H2BC5 -9371.0
H3-3A -9260.0
H4C16 -9179.0
H2AC4 -9092.0
H2BC1 -8504.0
KAT2B -8472.0
H4C13 -8401.0
H3-3B -8363.0
H3C8 -8260.0
H2BC3 -8237.0
H2BC8 -8108.0
H3C11 -7686.0
PRMT1 -7681.0
AGO3 -7679.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
TNRC6B -7491.0
H2AJ -7338.0
NR4A3 -6991.0
H2BC10 -6977.0
H3C3 -6933.0
CBFB -6875.0
ASH2L -6843.0
H3C12 -6825.0
H2AC8 -6733.0
PRKCQ -6522.0
H2AC18 -6516.5
H2AC19 -6516.5
H2BC14 -6126.0
AGO1 -6050.0
KMT2D -5933.0
H3C2 -5478.0
H2AC7 -5340.5
H2BC7 -5340.5
MOV10 -4504.0
TNRC6C -4438.0
ZFPM1 -4194.0
H4C4 -4007.0
DPY30 -3892.0
H2BC21 -3732.0
H4C6 -3568.0
H2AC14 -3377.0
H3C4 -3045.0
KMT2E -2890.0
SETD1A -2122.0
SIN3A -1392.0
KMT2A -1135.0
H3C10 -1128.0
H4C12 -1092.0
H4C2 -859.0
H2BC13 1.0
WDR5 156.0
KMT2C 917.0
H4C8 1444.0
SETD1B 1496.0
H2BC26 1619.0
ITGA2B 1860.0
TNRC6A 1957.0
H2BC15 2203.0
H2BC4 2363.0
H4C1 2583.0
H2AC20 3179.0
SIN3B 3728.0
PRMT6 3920.0
H2BC17 4130.0
H2BC11 4657.0
H3C1 4735.0
HDAC1 4949.0
H4C5 5401.0
H2AZ2 5485.0
THBS1 5846.0
H2AC6 6426.0
H2AX 6737.0
PF4 8611.0
MYL9 9962.0
KMT2B 10017.0



REACTOME_CHROMATIN_MODIFYING_ENZYMES

REACTOME_CHROMATIN_MODIFYING_ENZYMES
558
set REACTOME_CHROMATIN_MODIFYING_ENZYMES
setSize 252
pANOVA 5.7e-08
s.dist -0.199
p.adjustANOVA 3.6e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708
H3C6 -10650
KAT8 -10584
KAT6A -10229
H4C3 -9942
EP300 -9776
SUV39H2 -9588
H2BC12 -9581
H4C11 -9492
H4C9 -9486
RBBP5 -9393
H2BC5 -9371
TADA1 -9367
H2AC16 -9348
RCOR1 -9289
SMARCC2 -9250
H4C16 -9179
H2AC4 -9092
KMT5A -9054
ENY2 -8830

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
H3C6 -10650.0
KAT8 -10584.0
KAT6A -10229.0
H4C3 -9942.0
EP300 -9776.0
SUV39H2 -9588.0
H2BC12 -9581.0
H4C11 -9492.0
H4C9 -9486.0
RBBP5 -9393.0
H2BC5 -9371.0
TADA1 -9367.0
H2AC16 -9348.0
RCOR1 -9289.0
SMARCC2 -9250.0
H4C16 -9179.0
H2AC4 -9092.0
KMT5A -9054.0
ENY2 -8830.0
GATAD2B -8745.0
H2BC1 -8504.0
KAT2B -8472.0
NCOR2 -8471.0
KAT7 -8468.0
H4C13 -8401.0
H3C8 -8260.0
H2BC3 -8237.0
SMARCA2 -8188.0
H2BC8 -8108.0
TAF12 -8042.0
PHF20 -8020.0
NCOA2 -7957.0
COPRS -7870.0
KDM3B -7785.0
SUPT20H -7744.0
H3C11 -7686.0
PRMT1 -7681.0
EZH2 -7675.0
SAP18 -7662.0
ATXN7L3 -7628.0
SETD7 -7582.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
H2AC21 -7374.0
H2AJ -7338.0
SAP30 -7138.0
PBRM1 -7061.0
EED -7009.0
H2BC10 -6977.0
H3C3 -6933.0
ASH2L -6843.0
H3C12 -6825.0
H2AC8 -6733.0
TADA2A -6613.0
H2AC18 -6516.5
H2AC19 -6516.5
KDM2A -6500.0
NSD3 -6457.0
ARID2 -6420.0
KANSL1 -6374.0
ASH1L -6298.0
H2AC1 -6275.0
HDAC10 -6199.0
NSD1 -6165.0
H2BC14 -6126.0
KDM4C -6032.0
VPS72 -6028.0
KMT2D -5933.0
ATF7IP -5905.0
MBD3 -5903.0
SUDS3 -5886.0
KMT5C -5860.0
KAT6B -5847.0
ATXN7 -5790.0
PADI2 -5691.0
YEATS2 -5664.0
HDAC2 -5534.0
H3C2 -5478.0
ELP1 -5354.0
H2AC7 -5340.5
H2BC7 -5340.5
KDM2B -5338.0
ARID4A -5327.0
ING4 -5232.0
H2AC12 -5204.0
CDK4 -5202.0
KDM5A -5199.0
KDM5B -5100.0
KAT5 -5079.0
SMARCE1 -4940.0
KDM4B -4912.0
SMARCD1 -4900.0
SETD2 -4752.0
MEAF6 -4676.0
ELP4 -4617.0
BRWD1 -4544.0
PHF2 -4396.0
PHF21A -4143.0
TBL1XR1 -4015.0
H4C4 -4007.0
KDM4A -3935.0
ARID1B -3929.0
DPY30 -3892.0
RUVBL1 -3783.0
MECOM -3753.0
H2BC21 -3732.0
JAK2 -3714.0
JMJD6 -3665.0
RELA -3661.0
NCOA1 -3650.0
KDM7A -3644.0
NSD2 -3599.0
H4C6 -3568.0
MRGBP -3492.0
ARID5B -3449.0
H2AC14 -3377.0
SAP130 -3322.0
BRPF3 -3268.0
KDM6B -3253.0
TAF9 -3142.0
SMYD2 -3103.0
EHMT2 -3061.0
H3C4 -3045.0
MTA2 -2984.0
KMT2E -2890.0
TAF5L -2874.0
JADE1 -2864.0
PRMT3 -2739.0
TADA3 -2648.0
GPS2 -2644.0
SMARCD2 -2528.0
SGF29 -2525.0
EP400 -2470.0
GATAD2A -2405.0
EPC1 -2346.0
KANSL2 -2218.0
SETD1A -2122.0
BRMS1 -2063.0
PRDM9 -1927.0
ZZZ3 -1823.0
SETDB1 -1766.0
MBIP -1710.0
BRD8 -1645.0
CLOCK -1601.0
SETD6 -1517.0
USP22 -1360.0
TAF6L -1278.0
PRMT7 -1270.0
MTA1 -1189.0
PADI4 -1143.0
KMT2A -1135.0
H3C10 -1128.0
EHMT1 -1095.0
H4C12 -1092.0
KDM1A -970.0
H4C2 -859.0
KMT5B -765.0
REST -668.0
ACTB -471.0
NFKB1 -285.0
ARID1A -221.0
H2AC17 -112.0
ING3 -55.0
RBBP4 -33.0
H2BC13 1.0
YEATS4 48.0
HMG20B 51.0
HAT1 66.0
PAX3 129.0
H2AC25 146.0
WDR5 156.0
ACTL6A 268.0
CHD3 338.0
PRMT5 482.0
ACTL6B 524.0
MSL1 653.0
ING5 674.0
ATF2 857.0
KMT2C 917.0
CCND1 1122.0
SETD3 1281.0
ARID4B 1294.0
H4C8 1444.0
KDM3A 1459.0
SETD1B 1496.0
DOT1L 1526.0
DNMT3A 1573.0
SAP30L 1574.0
H2BC26 1619.0
MCRS1 1757.0
NCOR1 1776.0
H2AC15 1986.0
H2BC15 2203.0
BRD1 2222.0
SUPT7L 2255.0
KDM4D 2335.0
SUPT3H 2343.0
H2BC4 2363.0
NFKB2 2472.0
SETDB2 2554.0
HDAC3 2573.0
H4C1 2583.0
TRRAP 2723.0
SMYD3 2822.0
AEBP2 3010.0
H2AC20 3179.0
RUVBL2 3352.0
WDR77 3485.0
TAF10 3510.0
ELP2 3518.0
RIOX2 3658.0
DR1 3771.0
KAT2A 3907.0
PRMT6 3920.0
H2BC17 4130.0
ELP6 4138.0
SMARCA4 4350.0
JADE2 4603.0
H2BC11 4657.0
H3C1 4735.0
MORF4L1 4884.0
HDAC1 4949.0
DMAP1 5271.0
SMARCD3 5277.0
ELP3 5279.0
TADA2B 5305.0
H4C5 5401.0
ELP5 5436.0
H2AZ2 5485.0
MSL2 5565.0
CREBBP 5734.0
SUZ12 5843.0
CHD4 6248.0
H2AC6 6426.0
H2AX 6737.0
MTA3 6867.0
BRPF1 6984.0
SMARCC1 7024.0
KANSL3 7212.0
RPS2 7273.0
PRDM16 7727.0
CARM1 7764.0
PADI1 8025.0
KDM1B 8241.0
H2AC13 8584.0
PADI3 9023.0
H2AC11 9249.0
PADI6 9926.0
KMT2B 10017.0
SMARCB1 10098.0



REACTOME_MITOTIC_PROMETAPHASE

REACTOME_MITOTIC_PROMETAPHASE
1094
set REACTOME_MITOTIC_PROMETAPHASE
setSize 194
pANOVA 8.58e-08
s.dist -0.223
p.adjustANOVA 5.22e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
CSNK1E -10595
TUBA3D -10346
DCTN2 -10239
YWHAG -10207
TUBB4B -10078
TUBG2 -10039
CSNK2A1 -9812
SMC2 -9640
CEP41 -9604
DYNLL1 -9489
DYNC1LI1 -9445
NEK9 -9304
CLIP1 -8978
CSNK2A2 -8850
TUBB4A -8809
CENPA -8800
PDS5A -8763
NEK7 -8538
PPP2R5B -8503
HAUS2 -8502

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CSNK1E -10595
TUBA3D -10346
DCTN2 -10239
YWHAG -10207
TUBB4B -10078
TUBG2 -10039
CSNK2A1 -9812
SMC2 -9640
CEP41 -9604
DYNLL1 -9489
DYNC1LI1 -9445
NEK9 -9304
CLIP1 -8978
CSNK2A2 -8850
TUBB4A -8809
CENPA -8800
PDS5A -8763
NEK7 -8538
PPP2R5B -8503
HAUS2 -8502
NME7 -8404
PCM1 -8345
NSL1 -8302
CNTRL -8294
CENPQ -8231
MZT2A -8124
NDE1 -7893
NEDD1 -7817
KIF2C -7797
ZWINT -7770
CCNB2 -7768
NUDC -7747
CEP72 -7656
CEP43 -7565
ZWILCH -7287
ODF2 -7132
CEP78 -7050
CEP70 -7040
BUB1B -6938
TUBAL3 -6859
TUBA4A -6826
CDK5RAP2 -6558
DYNC1I2 -6523
TUBB3 -6481
TUBA4B -6407
CLASP2 -6389
SPC24 -6225
TUBGCP3 -6224
KIF2B -6144
AKAP9 -6138
SEC13 -6136
NEK2 -6109
ACTR1A -6083
TUBA1A -6069
SDCCAG8 -6001
SMC4 -5947
PAFAH1B1 -5709
ITGB3BP -5665
PLK4 -5568
HAUS3 -5461
TUBB2A -5397
HAUS4 -5369
SKA1 -5357
TAOK1 -5276
NCAPD2 -5155
NDC80 -5070
CCP110 -4990
SGO2 -4989
CENPC -4957
KNL1 -4647
TUBB6 -4561
XPO1 -4530
CEP76 -4407
DYNC1H1 -4301
CENPP -4279
RCC2 -4121
CEP63 -4104
CENPT -4073
TUBGCP2 -4000
NUP133 -3990
NDEL1 -3912
CENPO -3864
CKAP5 -3856
PPP2R5E -3635
HAUS1 -3554
SFI1 -3534
KIF18A -3490
RPS27 -3484
NCAPG -3211
TUBA1C -3186
DSN1 -3120
STAG1 -3119
AURKB -2861
HAUS8 -2836
CDK1 -2730
SGO1 -2709
NUP98 -2703
CENPL -2691
PMF1 -2655
CLASP1 -2556
TUBA8 -2524
NUP160 -2508
INCENP -2499
PPP2CB -2471
CEP131 -2380
HSP90AA1 -2213
CSNK2B -2185
SPC25 -2166
DYNC1I1 -2149
CENPE -2121
AHCTF1 -2112
TUBB2B -2109
PDS5B -2101
DCTN1 -2023
B9D2 -1934
NUMA1 -1745
RAD21 -1610
CSNK1D -1577
PLK1 -1530
SMC3 -1334
PPP2R5D -1303
SSNA1 -1082
ALMS1 -1048
TUBB -950
PRKACA -933
NUP37 -825
CENPN -774
CENPM -681
RANGAP1 -663
MIS12 -582
PCNT -547
NUP43 -528
CEP57 -401
TUBA3C -374
TUBGCP5 -373
MAD1L1 -288
TUBA3E -95
TUBG1 -30
BUB1 3
CDCA5 37
CEP290 127
NUP85 327
PPP2R5C 395
PPP1CC 455
CENPH 476
CEP152 501
BUB3 813
WAPL 1021
EML4 1046
YWHAE 1068
RANBP2 1258
NUF2 1321
TUBGCP6 1346
MAPRE1 1433
PPP2R5A 1963
CEP192 1984
NCAPH 2016
PPP2R1B 2037
NUP107 2333
SKA2 2357
CENPJ 2408
PPP2CA 2625
DYNC1LI2 2640
MZT2B 2863
CENPS 2903
CDC20 2914
CEP164 3190
CCNB1 3317
HAUS6 3637
TUBGCP4 3739
CENPU 3842
KIF2A 3843
SPDL1 3844
KNTC1 3867
CENPF 4067
PRKAR2B 4569
TUBA1B 4671
NEK6 4718
HAUS5 5396
TUBB1 5561
CEP250 5608
MZT1 5950
CEP135 6155
ZW10 6165
PPP2R1A 6221
MAD2L1 7226
CDCA8 7291
CENPK 7336
BIRC5 7359
DCTN3 7804
SEH1L 8440
DYNLL2 9125
NINL 9408
TUBB8 10871



REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP

REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP
502
set REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP
setSize 104
pANOVA 1.06e-07
s.dist -0.302
p.adjustANOVA 6.24e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS6KA1 -10777
H2BC6 -10708
H3C6 -10650
CXCL8 -10206
IL6 -10121
H4C3 -9942
H2BC12 -9581
UBC -9558
H4C11 -9492
H4C9 -9486
H2BC5 -9371
H3-3A -9260
H4C16 -9179
H2AC4 -9092
UBE2E1 -9071
MAPK1 -8617
CDC16 -8598
H2BC1 -8504
H4C13 -8401
H3-3B -8363

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS6KA1 -10777.0
H2BC6 -10708.0
H3C6 -10650.0
CXCL8 -10206.0
IL6 -10121.0
H4C3 -9942.0
H2BC12 -9581.0
UBC -9558.0
H4C11 -9492.0
H4C9 -9486.0
H2BC5 -9371.0
H3-3A -9260.0
H4C16 -9179.0
H2AC4 -9092.0
UBE2E1 -9071.0
MAPK1 -8617.0
CDC16 -8598.0
H2BC1 -8504.0
H4C13 -8401.0
H3-3B -8363.0
H3C8 -8260.0
H2BC3 -8237.0
H2BC8 -8108.0
CDK6 -8085.0
CDK2 -8046.0
CDKN2A -7757.0
CDKN2B -7709.0
H3C11 -7686.0
CDKN2C -7581.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
FZR1 -7430.0
H2AJ -7338.0
H2BC10 -6977.0
H3C3 -6933.0
CEBPB -6830.0
H3C12 -6825.0
CDKN1B -6757.0
H2AC8 -6733.0
H2AC18 -6516.5
H2AC19 -6516.5
H2BC14 -6126.0
CDC26 -6099.0
ANAPC10 -6095.0
ANAPC7 -5877.0
VENTX -5482.0
H3C2 -5478.0
H2AC7 -5340.5
H2BC7 -5340.5
CDK4 -5202.0
CDKN1A -5005.0
STAT3 -4580.0
CDC23 -4153.0
CDC27 -4025.0
H4C4 -4007.0
H2BC21 -3732.0
RELA -3661.0
MAPK7 -3657.0
H4C6 -3568.0
H2AC14 -3377.0
EHMT2 -3061.0
H3C4 -3045.0
CCNA1 -2724.0
ANAPC5 -2079.0
IGFBP7 -1265.0
H3C10 -1128.0
EHMT1 -1095.0
H4C12 -1092.0
H4C2 -859.0
UBE2C -706.0
ANAPC15 -493.0
NFKB1 -285.0
H2BC13 1.0
UBE2S 7.0
FOS 612.0
ANAPC11 853.0
ANAPC4 1161.0
UBB 1320.0
H4C8 1444.0
H2BC26 1619.0
ANAPC16 2196.0
H2BC15 2203.0
RPS27A 2313.0
H2BC4 2363.0
H4C1 2583.0
UBA52 2643.0
JUN 3045.0
H2AC20 3179.0
H2BC17 4130.0
RPS6KA2 4142.0
ANAPC1 4318.0
ANAPC2 4548.0
H2BC11 4657.0
H3C1 4735.0
CCNA2 5235.0
H4C5 5401.0
H2AZ2 5485.0
H2AC6 6426.0
H2AX 6737.0
UBE2D1 7063.0
MAPK3 7947.0
CDKN2D 8586.0
IL1A 10212.0



REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS

REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS
901
set REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS
setSize 113
pANOVA 2.17e-07
s.dist -0.282
p.adjustANOVA 1.23e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708
H3C6 -10650
HOXB2 -10561
POLR2C -10372
HOXB3 -10319
RARG -9989
RARA -9950
H4C3 -9942
HOXB4 -9790
EP300 -9776
H2BC12 -9581
H4C11 -9492
H4C9 -9486
HOXA4 -9399
RBBP5 -9393
H2BC5 -9371
H3-3A -9260
H4C16 -9179
H2AC4 -9092
MEIS1 -8723

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
H3C6 -10650.0
HOXB2 -10561.0
POLR2C -10372.0
HOXB3 -10319.0
RARG -9989.0
RARA -9950.0
H4C3 -9942.0
HOXB4 -9790.0
EP300 -9776.0
H2BC12 -9581.0
H4C11 -9492.0
H4C9 -9486.0
HOXA4 -9399.0
RBBP5 -9393.0
H2BC5 -9371.0
H3-3A -9260.0
H4C16 -9179.0
H2AC4 -9092.0
MEIS1 -8723.0
H2BC1 -8504.0
H4C13 -8401.0
H3-3B -8363.0
H3C8 -8260.0
H2BC3 -8237.0
H2BC8 -8108.0
POLR2K -7697.0
H3C11 -7686.0
EZH2 -7675.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
H2AJ -7338.0
POLR2A -7267.0
EED -7009.0
H2BC10 -6977.0
H3C3 -6933.0
ASH2L -6843.0
H3C12 -6825.0
H2AC8 -6733.0
RXRA -6640.0
H2AC18 -6516.5
H2AC19 -6516.5
PAXIP1 -6423.0
H2BC14 -6126.0
KMT2D -5933.0
MAFB -5767.0
EGR2 -5715.0
HOXC4 -5640.0
HOXD4 -5519.0
H3C2 -5478.0
H2AC7 -5340.5
H2BC7 -5340.5
YY1 -5148.0
HOXD1 -4360.0
PAGR1 -4075.0
H4C4 -4007.0
CTCF -3951.0
HOXD3 -3841.0
H2BC21 -3732.0
PBX1 -3706.0
H4C6 -3568.0
H2AC14 -3377.0
H3C4 -3045.0
HOXA1 -2980.0
POLR2I -2893.0
POLR2B -2615.0
NCOA3 -2235.0
PAX6 -2127.0
POLR2G -1251.0
CNOT6 -1230.0
H3C10 -1128.0
H4C12 -1092.0
HOXB1 -943.0
H4C2 -859.0
NCOA6 -707.0
RBBP4 -33.0
H2BC13 1.0
WDR5 156.0
CNOT9 886.0
KMT2C 917.0
PCGF2 970.0
H4C8 1444.0
H2BC26 1619.0
NCOR1 1776.0
POLR2L 1891.0
PKNOX1 1962.0
H2BC15 2203.0
H2BC4 2363.0
HOXA2 2396.0
HDAC3 2573.0
H4C1 2583.0
JUN 3045.0
POLR2H 3091.0
H2AC20 3179.0
AJUBA 3376.0
RARB 3559.0
POLR2F 3701.0
H2BC17 4130.0
POLR2E 4421.0
H2BC11 4657.0
H3C1 4735.0
H4C5 5401.0
H2AZ2 5485.0
CREBBP 5734.0
SUZ12 5843.0
H2AC6 6426.0
H2AX 6737.0
HOXA3 6803.0
PIAS2 7256.0
ZNF335 7689.0
POLR2D 8105.0
POLR2J 10234.0



REACTOME_METABOLISM_OF_RNA

REACTOME_METABOLISM_OF_RNA
1313
set REACTOME_METABOLISM_OF_RNA
setSize 675
pANOVA 2.39e-07
s.dist -0.117
p.adjustANOVA 1.31e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
TNFSF13 -10826
CSNK1E -10595
PSMB7 -10578
TYW1 -10522
POM121C -10473
POLR2C -10372
RBM22 -10361
PRKCD -10313
DDX39B -10247
ERCC3 -10242
WDR43 -10162
SF3B4 -10034
NXF1 -9962
ZMAT5 -9855
ERI1 -9827
RPL29 -9703
U2AF1L4 -9688
THOC1 -9668
APOBEC3C -9652
FBL -9620

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TNFSF13 -10826.0
CSNK1E -10595.0
PSMB7 -10578.0
TYW1 -10522.0
POM121C -10473.0
POLR2C -10372.0
RBM22 -10361.0
PRKCD -10313.0
DDX39B -10247.0
ERCC3 -10242.0
WDR43 -10162.0
SF3B4 -10034.0
NXF1 -9962.0
ZMAT5 -9855.0
ERI1 -9827.0
RPL29 -9703.0
U2AF1L4 -9688.0
THOC1 -9668.0
APOBEC3C -9652.0
FBL -9620.0
RPP30 -9580.0
UBC -9558.0
PSMD5 -9539.0
CNOT10 -9481.0
RPLP1 -9411.0
RIOK2 -9396.0
LSM1 -9337.0
DDX42 -9326.0
ADAT3 -9308.0
GLE1 -9211.0
DDX1 -9204.0
RPS23 -9195.0
SNRNP48 -9182.0
BCAS2 -9146.0
SENP3 -9140.0
HSPA8 -9110.0
RAE1 -9026.0
HNRNPU -9006.0
UTP11 -8945.0
CTNNBL1 -8942.0
SMG5 -8923.0
ANP32A -8874.0
SYMPK -8870.0
DDX21 -8858.0
TP53RK -8826.0
C9orf78 -8805.0
UTP6 -8787.0
FCF1 -8778.0
ZC3H11A -8724.0
RPS29 -8722.0
RPPH1 -8715.0
SF3B2 -8687.0
TRMT6 -8659.0
SNRNP27 -8586.0
SART1 -8575.0
PABPN1 -8563.0
TRA2B -8433.0
PPIH -8416.0
TSEN54 -8352.0
PUS1 -8279.0
NOL12 -8232.0
PPIL2 -8217.0
CNOT8 -8208.0
EXOSC5 -8187.0
HNRNPH1 -8174.0
GEMIN7 -8160.0
UTP3 -8145.0
DCP1A -8137.0
WDR70 -8129.0
THADA -8123.0
PSME1 -8101.0
MRM1 -8071.0
GNL3 -8065.0
RPL11 -8055.0
SNRNP25 -8015.0
PSMA6 -7988.0
EXOSC7 -7984.0
KRR1 -7965.0
SNRPB -7928.0
CNOT6L -7826.0
NUP50 -7820.0
RPP25 -7788.0
RBM25 -7756.0
MAPKAPK2 -7751.0
NSUN2 -7698.0
POLR2K -7697.0
DHX16 -7671.0
SAP18 -7662.0
NUP93 -7632.0
HNRNPD -7621.0
GSPT1 -7615.0
PRKRIP1 -7598.0
UTP18 -7525.0
RPL22 -7474.0
XRN1 -7449.0
CPSF3 -7434.0
LENG1 -7397.0
HSPA1A -7384.0
CPSF2 -7300.0
POLR2A -7267.0
CTU1 -7266.0
SDE2 -7215.0
RRP9 -7173.0
HBS1L -7167.0
RTCB -7152.0
IGF2BP3 -7129.0
SNRNP40 -7128.0
PATL1 -7097.0
POP7 -7007.0
FAU -6993.0
ZCRB1 -6939.0
CWF19L2 -6911.0
PAN3 -6909.0
RPL27 -6893.0
APOBEC3H -6885.0
RIOK3 -6856.0
RPL23 -6779.0
AQR -6765.0
RPL21 -6753.0
GPATCH1 -6681.0
PCBP1 -6673.0
PHF5A -6667.0
ACIN1 -6648.0
UTP20 -6647.0
LSM11 -6638.0
HNRNPL -6636.0
PRPF19 -6624.0
RCL1 -6585.0
RPS9 -6580.0
NXT1 -6561.0
RPL34 -6560.0
GTF2F1 -6537.0
LTV1 -6484.0
PSMD13 -6393.0
PPP2R2A -6359.0
CCDC12 -6350.0
ALYREF -6332.0
RPL10A -6330.0
SF3B1 -6304.0
GEMIN2 -6263.0
RBM42 -6259.0
LSM8 -6253.0
ISY1 -6239.0
PSMC6 -6219.0
HNRNPF -6181.0
EDC3 -6180.0
SMG6 -6177.0
YWHAZ -6164.0
TFB1M -6153.0
SEC13 -6136.0
PELP1 -6135.0
PSME2 -6132.0
CCNH -6119.0
CPSF6 -6065.0
HNRNPA1 -6029.0
DDX23 -6023.0
GEMIN4 -6013.0
EPRS1 -5958.0
NUP155 -5935.0
SMN1 -5909.5
SMN2 -5909.5
METTL14 -5889.0
APOBEC3A -5833.0
RBM28 -5823.0
MTO1 -5806.0
PABPC1 -5801.0
DDX49 -5781.0
DDX20 -5707.0
WDR36 -5661.0
TNPO1 -5632.0
HSPB1 -5590.0
FYTTD1 -5498.0
RPS20 -5483.0
RNGTT -5471.0
OSGEP -5439.0
UTP25 -5343.0
NUP153 -5310.0
EXOSC4 -5302.0
POM121 -5300.0
SF3B5 -5193.0
PDCD7 -5128.0
PAPOLA -5086.0
RPS26 -4941.0
SNRPD3 -4881.0
THOC6 -4859.0
IGF2BP1 -4792.0
LUC7L3 -4757.0
RPL9 -4728.0
PHAX -4711.0
TYW3 -4701.0
USP39 -4636.0
LSM3 -4634.0
SUGP1 -4611.0
PSMB10 -4606.0
RPL18 -4575.0
XPO1 -4530.0
POP4 -4525.0
TUT7 -4511.0
DCPS -4471.0
BMS1 -4441.0
MAPK14 -4437.0
AKT1 -4393.0
DCP1B -4384.0
WDR75 -4383.0
GTF2H5 -4378.0
PSMB2 -4344.0
SNRNP70 -4336.0
C2orf49 -4287.0
TRMT11 -4244.0
CASC3 -4204.0
DHX15 -4146.0
NUP188 -4141.0
CDC5L -4120.0
TRMT61A -4105.0
PSMD7 -4057.0
PUF60 -4028.0
NUP133 -3990.0
PPIL4 -3967.0
BOP1 -3956.0
RPL15 -3918.0
SF3A2 -3911.0
CACTIN -3905.0
ADARB1 -3871.0
TGS1 -3798.0
APOBEC3B -3770.0
NSUN4 -3743.0
CPSF7 -3727.0
DHX37 -3710.0
GAR1 -3666.0
GTF2H1 -3642.0
RPL26 -3628.0
SLU7 -3585.0
DNAJC8 -3578.0
RPL10L -3574.0
SRSF10 -3543.0
CNOT7 -3535.0
RPS27 -3484.0
BUD23 -3471.0
PPIG -3461.0
PSMA7 -3416.0
PRPF40A -3365.0
LSM4 -3348.0
CDKAL1 -3332.0
RPL30 -3326.0
CHERP -3258.0
WTAP -3257.0
PSME3 -3245.0
MNAT1 -3244.0
GEMIN6 -3213.0
CNOT1 -3172.0
NUP42 -3160.0
PARN -3133.0
BUD31 -3127.0
SNRPN -3106.0
UPF2 -3075.0
ADAR -3058.0
TSEN15 -3043.0
DHX38 -3019.0
PRPF6 -3018.0
NOC4L -3009.0
XPOT -2986.0
TRNT1 -2932.0
RBM8A -2924.0
HNRNPC -2910.0
MAGOHB -2907.0
MTREX -2897.0
POLR2I -2893.0
SMG8 -2886.0
XRN2 -2832.0
PSMC4 -2787.0
THOC5 -2762.0
SNW1 -2756.0
NUP98 -2703.0
ZNF830 -2680.0
EIF4A1 -2669.0
DDX39A -2652.0
CNOT2 -2651.0
SNRPF -2638.0
POLR2B -2615.0
TRMT13 -2600.0
LSM5 -2586.0
GTF2H3 -2584.0
ELAVL1 -2558.0
RPL4 -2541.0
TSEN34 -2537.0
KHSRP -2535.0
DDX46 -2514.0
NUP160 -2508.0
HNRNPR -2424.0
RPS6 -2406.0
GEMIN5 -2399.0
NSRP1 -2398.0
IGF2BP2 -2378.0
LSM2 -2376.0
RIOK1 -2332.0
THG1L -2311.0
PRORP -2284.0
UPF1 -2252.0
EIF4A2 -2243.0
TCERG1 -2201.0
SEM1 -2183.0
NUP35 -2059.0
TRDMT1 -2055.0
PSMB6 -1996.0
PSMD14 -1965.0
SNIP1 -1964.0
PNO1 -1941.0
SF3B3 -1922.0
MPHOSPH6 -1918.0
SMU1 -1811.0
YBX1 -1801.0
BUD13 -1795.0
FAM32A -1792.0
PRPF18 -1777.0
RPL24 -1718.0
HNRNPA3 -1663.0
EMG1 -1619.0
SRSF11 -1618.0
CSNK1D -1577.0
LSM7 -1558.0
WDR3 -1514.0
NOP14 -1499.0
RBM39 -1476.0
RPS25 -1469.0
ALKBH8 -1454.0
PSMD9 -1453.0
RPL5 -1417.0
SNRNP200 -1412.0
NCBP2 -1379.0
RPL18A -1362.0
RPS19 -1355.0
CCAR1 -1353.0
PSMC5 -1352.0
PPIL3 -1350.0
RPL13 -1344.0
CNOT4 -1314.0
SNRPA1 -1305.0
LSM6 -1289.0
POLR2G -1251.0
CNOT6 -1230.0
PSMB4 -1200.0
SNU13 -1155.0
POLDIP3 -1130.0
TNKS1BP1 -1066.0
SNRPB2 -1049.0
TUT4 -1012.0
PCBP2 -993.0
PSMA3 -989.0
IK -978.0
AAAS -910.0
NIP7 -868.0
PSMC2 -840.0
CPSF1 -834.0
NUP37 -825.0
RPL27A -824.0
TXNL4A -820.0
ADAT2 -800.0
NAT10 -753.0
PES1 -697.0
RPS15A -688.0
PSMD6 -684.0
MAGOH -667.0
RPL37A -652.0
SET -625.0
RPS27L -610.0
PLRG1 -554.0
NUP43 -528.0
PSMD11 -524.0
NUP214 -489.0
PSMB1 -483.0
HNRNPA2B1 -469.0
PSMA4 -398.0
SMG1 -383.0
NCBP1 -338.0
TFIP11 -334.0
EXOSC1 -322.0
RPL35 -307.0
RPL28 -294.0
PRPF3 -292.0
U2SURP -260.0
BYSL -220.0
PRPF4 -205.0
METTL1 -190.0
RPS8 -175.0
TRMT12 -170.0
EXOSC3 -159.0
CWC22 -93.0
RPL35A -84.0
PCF11 -6.0
HNRNPM 25.0
FUS 40.0
PSMD4 55.0
DHX35 58.0
SNRNP35 97.0
CLNS1A 111.0
RPS16 186.0
RBM17 241.0
DCAF13 243.0
NCL 271.0
RPP21 274.0
SKIC8 283.0
IMP3 289.0
ZMAT2 299.0
EBNA1BP2 313.0
PRPF8 325.0
NUP85 327.0
CWC27 362.0
PSMD12 373.0
EXOSC10 383.0
RPL26L1 397.0
ZFP36L1 444.0
C1D 451.0
FIP1L1 462.0
TSR1 467.0
RPSA 473.0
PRMT5 482.0
TRMT10C 483.0
GTPBP3 513.0
SYF2 521.0
DIS3 523.0
TSEN2 525.0
GTF2F2 536.0
EIF4G1 546.0
PSMF1 550.0
FTSJ3 577.0
EIF4A3 601.0
NOL11 609.0
EXOSC2 621.0
RPL6 651.0
WDR18 671.0
WBP4 680.0
RBM7 681.0
RPL12 711.0
DCP2 726.0
SNRPD2 736.0
EDC4 753.0
CLP1 765.0
PSMA2 776.0
SF1 827.0
CTU2 848.0
CNOT9 886.0
SRRM2 903.0
HEATR1 911.0
ZBTB8OS 953.0
SRSF6 956.0
RTRAF 1012.0
NUP54 1027.0
SRSF4 1082.0
PSMD3 1087.0
PSMB9 1093.0
DDX6 1113.0
RPS15 1149.0
MRM3 1257.0
RANBP2 1258.0
UBB 1320.0
SMNDC1 1347.0
YJU2 1354.0
RPL41 1365.0
EXOSC8 1377.0
RNPC3 1413.0
PPIL1 1424.0
RRP36 1445.0
SRSF2 1473.0
SARNP 1480.0
WBP11 1506.0
PNRC2 1532.0
THUMPD1 1586.0
PNN 1600.0
SRSF9 1611.0
QTRT2 1649.0
MFAP1 1657.0
SRSF8 1664.0
WDR46 1678.0
SMG7 1679.0
PTBP1 1682.0
SMG9 1722.0
CHTOP 1723.0
NOL6 1758.0
NUP88 1774.0
SUPT5H 1775.0
YWHAB 1797.0
RAN 1799.0
GCFC2 1827.0
RPS10 1837.0
PSMA5 1847.0
CDK7 1850.0
POLR2L 1891.0
PSMB8 2004.0
WDR12 2020.0
DIMT1 2056.0
RRP1 2064.0
APOBEC4 2076.0
RPLP2 2085.0
TEX10 2129.0
NUP210 2136.0
PPIE 2138.0
RPL19 2149.0
CDC40 2164.0
CWC15 2170.0
PSMA1 2177.0
EFTUD2 2217.0
ETF1 2290.0
HNRNPK 2304.0
CSTF2T 2312.0
RPS27A 2313.0
ERCC2 2323.0
NUP107 2333.0
NDC1 2461.0
CNOT11 2470.0
WDR33 2504.0
NSUN6 2510.0
PPP2CA 2625.0
UBA52 2643.0
MPHOSPH10 2679.0
CRNKL1 2719.0
RPP40 2727.0
TRMT10A 2739.0
PSMD8 2754.0
RPL14 2784.0
SRSF7 2820.0
MRM2 2845.0
TRMT61B 2854.0
TRMT112 2960.0
PRKCA 3022.0
THOC7 3051.0
SKIC3 3089.0
POLR2H 3091.0
PSME4 3100.0
CWC25 3132.0
PSMD1 3155.0
RPL38 3205.0
RPL32 3206.0
CSTF1 3207.0
TSR3 3295.0
PRPF38A 3313.0
RPS12 3386.0
WDR77 3485.0
PAIP1 3509.0
MTERF4 3514.0
DUS2 3525.0
TRMT44 3699.0
POLR2F 3701.0
CNOT3 3705.0
TRMT9B 3752.0
EIF4B 3762.0
RPS21 3781.0
ZNF473 3788.0
WDR4 3800.0
PAN2 3820.0
DHX9 3953.0
TPRKB 3957.0
UBL5 3979.0
EXOSC9 4007.0
DHX8 4058.0
RPL39L 4074.0
PUS7 4077.0
SRSF5 4080.0
RPS24 4090.0
SKIC2 4091.0
RPL23A 4115.0
NOP10 4184.0
TRMT1 4207.0
NOP58 4321.0
POLR2E 4421.0
DDX5 4449.0
NUP58 4456.0
U2AF2 4467.0
UTP15 4484.0
RPS14 4497.0
SNRPE 4508.0
SF3B6 4509.0
PRPF31 4511.0
URM1 4587.0
SF3A1 4618.0
NOP2 4647.0
TRMU 4659.0
NHP2 4683.0
SNRPD1 4714.0
SRRM1 4756.0
PSMC1 4758.0
DDX41 4783.0
LCMT2 4786.0
SNUPN 4792.0
QTRT1 4819.0
RPL17 4856.0
PRCC 4873.0
NOP56 4929.0
RPL7 4972.0
RPS3A 4982.0
CPSF4 4996.0
PSMB3 5015.0
SRSF12 5086.0
APOBEC1 5143.0
RPL37 5203.0
SRSF3 5215.0
DDX47 5222.0
RPL8 5290.0
CSTF3 5325.0
PDCD11 5333.0
EIF4E 5430.0
UTP4 5433.0
RPL22L1 5560.0
RBM5 5671.0
UTP14C 5678.0
XAB2 5683.0
PSMC3 5724.0
RPS18 5744.0
PSMB5 5798.0
GTF2H4 5821.0
RPL36AL 5907.5
SF3A3 5989.0
RPS13 6012.0
RPL31 6025.0
TRMT5 6073.0
RPS5 6091.0
RPS28 6113.0
SNRPC 6148.0
SLBP 6194.0
PPP2R1A 6221.0
RPL3 6271.0
RPP38 6349.0
SNRPG 6360.0
PUS3 6399.0
FAM98B 6413.0
PWP2 6415.0
RPP14 6445.0
LSM10 6471.0
POP1 6482.0
ELAC2 6491.0
NUDT21 6524.0
ISG20L2 6543.0
METTL3 6588.0
RPS7 6631.0
POP5 6688.0
DDX52 6730.0
RPLP0 6807.0
NUP205 6912.0
NOL9 7026.0
RPL7A 7052.0
PPWD1 7100.0
TPR 7154.0
RNPS1 7215.0
RPS2 7273.0
TBL3 7395.0
IMP4 7413.0
SRRT 7538.0
SRSF1 7624.0
UPF3A 7677.0
NUP62 7697.0
PPP1R8 7720.0
RPS11 7972.0
TYW5 8039.0
POLR2D 8105.0
NT5C3B 8212.0
EXOSC6 8249.0
NOB1 8285.0
PSMD2 8298.0
SNRPA 8375.0
SEH1L 8440.0
RRP7A 8452.0
A1CF 8481.0
RPL36 8538.0
RNMT 8555.0
RPS3 8628.0
ADAT1 8857.0
PSMA8 8939.0
MAPK11 8999.0
ZFP36 9492.0
TRIT1 9541.0
APOBEC2 9782.0
RPL3L 10001.0
RPL13A 10152.5
PSMB11 10222.0
POLR2J 10234.0
THOC3 10456.0



REACTOME_DEUBIQUITINATION

REACTOME_DEUBIQUITINATION
1000
set REACTOME_DEUBIQUITINATION
setSize 260
pANOVA 3.3e-07
s.dist -0.184
p.adjustANOVA 1.75e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708
NOD1 -10608
PSMB7 -10578
NLRP3 -10484
ARRB1 -10157
NOD2 -10042
EP300 -9776
H2BC12 -9581
UBC -9558
PSMD5 -9539
TRIM4 -9532
TGFBR1 -9514
H2BC5 -9371
H2AC16 -9348
STAMBP -9242
TRAF6 -9223
H2AC4 -9092
GATA3 -9064
WDR48 -8887
DDB2 -8878

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
NOD1 -10608.0
PSMB7 -10578.0
NLRP3 -10484.0
ARRB1 -10157.0
NOD2 -10042.0
EP300 -9776.0
H2BC12 -9581.0
UBC -9558.0
PSMD5 -9539.0
TRIM4 -9532.0
TGFBR1 -9514.0
H2BC5 -9371.0
H2AC16 -9348.0
STAMBP -9242.0
TRAF6 -9223.0
H2AC4 -9092.0
GATA3 -9064.0
WDR48 -8887.0
DDB2 -8878.0
USP4 -8511.0
H2BC1 -8504.0
KAT2B -8472.0
MYSM1 -8456.0
MAT2B -8398.0
AXIN1 -8331.0
H2BC3 -8237.0
FOXK2 -8199.0
ACTR5 -8156.0
CDC25A -8146.0
H2BC8 -8108.0
PSME1 -8101.0
VDAC3 -8081.0
USP21 -8053.0
HIF1A -8044.0
WDR20 -8025.0
PSMA6 -7988.0
MBD5 -7912.0
USP24 -7887.0
STAM -7881.0
BIRC3 -7850.0
SIAH2 -7779.0
H2BC9 -7522.5
INO80D -7468.0
MUL1 -7466.0
USP15 -7442.0
H2AC21 -7374.0
RIPK2 -7234.0
TRAF2 -7035.0
STAMBPL1 -6995.0
H2BC10 -6977.0
USP10 -6976.0
YOD1 -6967.0
USP13 -6813.0
H2AC8 -6733.0
USP14 -6691.0
USP8 -6641.0
INO80C -6625.0
ASXL2 -6567.0
H2AC18 -6516.5
H2AC19 -6516.5
TNKS2 -6408.0
PSMD13 -6393.0
IDE -6323.0
H2AC1 -6275.0
TNKS -6268.0
FOXK1 -6256.0
PSMC6 -6219.0
SMAD7 -6202.0
RAD23A -6169.0
PSME2 -6132.0
H2BC14 -6126.0
USP25 -6033.0
SUDS3 -5886.0
RHOT1 -5836.0
POLB -5803.0
MBD6 -5802.0
ATXN7 -5790.0
BARD1 -5779.0
PTEN -5677.0
USP30 -5541.0
RHOA -5450.0
MAP3K7 -5435.0
USP47 -5412.0
OTUB1 -5394.0
H2AC7 -5340.5
H2BC7 -5340.5
H2AC12 -5204.0
YY1 -5148.0
UCHL3 -5147.0
ARRB2 -5102.0
ZRANB1 -5090.0
USP5 -5053.0
CCP110 -4990.0
BABAM2 -4972.0
CYLD -4946.0
NFKBIA -4831.0
ABRAXAS1 -4723.0
VCP -4679.0
PSMB10 -4606.0
USP37 -4536.0
SENP8 -4497.0
IFIH1 -4395.0
PSMB2 -4344.0
OTUB2 -4246.0
RIPK1 -4183.0
INO80 -4150.0
APC -4118.0
VDAC2 -4110.0
PSMD7 -4057.0
RUVBL1 -3783.0
TOMM70 -3759.0
USP42 -3751.0
H2BC21 -3732.0
PSMA7 -3416.0
H2AC14 -3377.0
PSME3 -3245.0
BECN1 -3236.0
SMAD2 -3052.0
RAD23B -3034.0
PSMC4 -2787.0
CDK1 -2730.0
CCNA1 -2724.0
AXIN2 -2653.0
TADA3 -2648.0
USP20 -2506.0
TGFB1 -2362.0
UIMC1 -2261.0
SEM1 -2183.0
PTRH2 -2170.0
MYC -2072.0
PSMB6 -1996.0
PSMD14 -1965.0
USP3 -1924.0
ASXL1 -1833.0
SMAD4 -1810.0
BABAM1 -1800.0
TNFAIP3 -1669.0
OTUD3 -1591.0
PSMD9 -1453.0
USP48 -1373.0
USP22 -1360.0
PSMC5 -1352.0
TRIM25 -1291.0
PSMB4 -1200.0
MDM2 -1085.0
UCHL5 -1051.0
PSMA3 -989.0
USP33 -884.0
PSMC2 -840.0
TP53 -831.0
TGFBR2 -747.0
SKP2 -722.0
PSMD6 -684.0
USP2 -680.0
UFD1 -637.0
TNIP1 -608.0
USP44 -605.0
PSMD11 -524.0
PSMB1 -483.0
ACTB -471.0
PSMA4 -398.0
TNIP3 -337.0
USP16 -320.0
SMURF2 -126.0
H2AC17 -112.0
MDM4 -86.0
H2BC13 1.0
USP19 54.0
PSMD4 55.0
VCPIP1 56.0
H2AC25 146.0
NEDD8 160.0
MAVS 190.0
ACTL6A 268.0
PSMD12 373.0
BRCA1 456.0
BAP1 506.0
PSMF1 550.0
OTUD7B 629.0
ACTR8 706.0
PSMA2 776.0
USP49 808.0
SMAD3 908.0
PSMD3 1087.0
PSMB9 1093.0
RNF146 1299.0
UBB 1320.0
VDAC1 1555.0
H2BC26 1619.0
STAM2 1734.0
MCRS1 1757.0
PSMA5 1847.0
ADRM1 1849.0
TFPT 1883.0
INO80E 1980.0
H2AC15 1986.0
PSMB8 2004.0
NFRKB 2125.0
PSMA1 2177.0
H2BC15 2203.0
SMAD1 2302.0
RPS27A 2313.0
H2BC4 2363.0
USP7 2400.0
UBA52 2643.0
ATXN3 2716.0
TRRAP 2723.0
RCE1 2732.0
USP18 2744.0
PSMD8 2754.0
USP12 2800.0
KEAP1 2884.0
CDC20 2914.0
JOSD1 3099.0
PSME4 3100.0
PSMD1 3155.0
H2AC20 3179.0
USP34 3189.0
FKBP8 3476.0
TAF10 3510.0
USP28 3712.0
TRAF3 3882.0
KAT2A 3907.0
PRKN 3999.0
H2BC17 4130.0
TOMM20 4183.0
RNF135 4294.0
INO80B 4630.0
H2BC11 4657.0
PSMC1 4758.0
ESR1 4769.0
PSMB3 5015.0
ADRB2 5167.0
CCNA2 5235.0
TADA2B 5305.0
RNF123 5418.0
PSMC3 5724.0
TAB1 5784.0
PSMB5 5798.0
RIGI 5819.0
SNX3 6408.0
H2AC6 6426.0
HGS 6652.0
JOSD2 6930.0
UBE2D1 7063.0
BIRC2 7080.0
CLSPN 7366.0
OTUD7A 7571.0
IL33 8001.0
CFTR 8023.0
KDM1B 8241.0
PSMD2 8298.0
TNIP2 8347.0
H2AC13 8584.0
PSMA8 8939.0
H2AC11 9249.0
ABRAXAS2 10161.0
UCHL1 10204.0
PSMB11 10222.0



REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING
320
set REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING
setSize 112
pANOVA 5.25e-07
s.dist -0.274
p.adjustANOVA 2.7e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708
H3C6 -10650
TMED2 -9959
AGO4 -9949
H4C3 -9942
MAML1 -9886
EP300 -9776
H2BC12 -9581
H4C11 -9492
H4C9 -9486
RUNX1 -9414
H2BC5 -9371
PRKCI -9311
H3-3A -9260
H4C16 -9179
H2AC4 -9092
B4GALT1 -8905
MIR200C -8532
TFDP2 -8530
H2BC1 -8504

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
H3C6 -10650.0
TMED2 -9959.0
AGO4 -9949.0
H4C3 -9942.0
MAML1 -9886.0
EP300 -9776.0
H2BC12 -9581.0
H4C11 -9492.0
H4C9 -9486.0
RUNX1 -9414.0
H2BC5 -9371.0
PRKCI -9311.0
H3-3A -9260.0
H4C16 -9179.0
H2AC4 -9092.0
B4GALT1 -8905.0
MIR200C -8532.0
TFDP2 -8530.0
H2BC1 -8504.0
KAT2B -8472.0
H4C13 -8401.0
H3-3B -8363.0
H3C8 -8260.0
H2BC3 -8237.0
TFDP1 -8155.0
H2BC8 -8108.0
ATP2A3 -8062.0
ST3GAL6 -7925.0
MIR449B -7763.0
H3C11 -7686.0
AGO3 -7679.0
POFUT1 -7557.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
SIRT6 -7506.0
TNRC6B -7491.0
H2AJ -7338.0
H2BC10 -6977.0
H3C3 -6933.0
H3C12 -6825.0
H2AC8 -6733.0
ATP2A2 -6583.0
H2AC18 -6516.5
H2AC19 -6516.5
SEL1L -6501.0
POGLUT1 -6356.0
ST3GAL4 -6174.0
H2BC14 -6126.0
AGO1 -6050.0
MIR449C -5573.0
H3C2 -5478.0
H2AC7 -5340.5
H2BC7 -5340.5
LFNG -5227.0
MAML2 -5093.0
RBPJ -4754.0
MOV10 -4504.0
E2F3 -4451.0
TNRC6C -4438.0
MIR449A -4135.0
H4C4 -4007.0
H2BC21 -3732.0
H4C6 -3568.0
H2AC14 -3377.0
H3C4 -3045.0
SNW1 -2756.0
MAML3 -2354.0
FURIN -1963.0
H3C10 -1128.0
H4C12 -1092.0
MFNG -1036.0
RAB6A -961.0
H4C2 -859.0
TP53 -831.0
H2BC13 1.0
ST3GAL3 852.0
CCND1 1122.0
H4C8 1444.0
H2BC26 1619.0
TNRC6A 1957.0
AGO2 2114.0
H2BC15 2203.0
H2BC4 2363.0
H4C1 2583.0
MIR302A 2792.5
JUN 3045.0
H2AC20 3179.0
NOTCH1 3378.0
MIR34B 3456.0
MIR150 3517.0
KAT2A 3907.0
H2BC17 4130.0
H2BC11 4657.0
H3C1 4735.0
NOTCH3 5228.0
H4C5 5401.0
NOTCH4 5452.0
H2AZ2 5485.0
CREBBP 5734.0
MIR206 5995.0
MIR181C 6236.0
MIR34C 6287.0
H2AC6 6426.0
H2AX 6737.0
E2F1 7131.0
ATP2A1 7985.0
MIR200B 8268.0
NOTCH2 9769.0
RFNG 10193.0
ELF3 10820.0



REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3
1585
set REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3
setSize 679
pANOVA 5.7e-07
s.dist -0.113
p.adjustANOVA 2.84e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A8 -10967
H2BC6 -10708
H3C6 -10650
RHOG -10627
ARHGAP11B -10619
LIMK2 -10612
GIT1 -10442
S100A9 -10359
TUBA3D -10346
PRKCD -10313
ARHGAP27 -10295
BCR -10280
DDX39B -10247
YWHAG -10207
CDC42 -10147
MTX1 -10107
TUBB4B -10078
RACGAP1 -10072
STOM -10067
TEX2 -10059

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A8 -10967.0
H2BC6 -10708.0
H3C6 -10650.0
RHOG -10627.0
ARHGAP11B -10619.0
LIMK2 -10612.0
GIT1 -10442.0
S100A9 -10359.0
TUBA3D -10346.0
PRKCD -10313.0
ARHGAP27 -10295.0
BCR -10280.0
DDX39B -10247.0
YWHAG -10207.0
CDC42 -10147.0
MTX1 -10107.0
TUBB4B -10078.0
RACGAP1 -10072.0
STOM -10067.0
TEX2 -10059.0
CDC42EP3 -10022.0
MAP3K11 -9966.0
H4C3 -9942.0
PLD1 -9920.0
LBR -9832.0
LIMK1 -9824.0
TAOK3 -9633.0
TPM4 -9622.0
WDR6 -9616.0
SLITRK3 -9594.0
PICALM -9587.0
H2BC12 -9581.0
IQGAP2 -9572.0
PIK3C3 -9526.0
SHKBP1 -9523.0
RAC1 -9520.0
H4C11 -9492.0
STBD1 -9490.0
DYNLL1 -9489.0
H4C9 -9486.0
WASL -9476.0
DYNC1LI1 -9445.0
SLC1A5 -9428.0
TAX1BP3 -9427.0
PIK3R1 -9422.0
POTEE -9388.0
H2BC5 -9371.0
STX5 -9365.0
CAVIN1 -9324.0
PFN1 -9274.0
H3-3A -9260.0
CDC25C -9256.0
NCKAP1L -9254.0
H4C16 -9179.0
COPS2 -9132.0
VAV1 -9126.0
H2AC4 -9092.0
FGD4 -9061.0
PARD6B -9025.0
CLIP1 -8978.0
SWAP70 -8843.0
ARHGEF39 -8842.0
TUBB4A -8809.0
CENPA -8800.0
NDUFS3 -8769.0
STK38 -8737.0
SYDE2 -8658.0
MAPK1 -8617.0
KCTD13 -8609.0
MYL12B -8541.0
ESYT1 -8529.0
H2BC1 -8504.0
PPP2R5B -8503.0
RHOH -8446.0
TRA2B -8433.0
GJA1 -8427.0
H4C13 -8401.0
CALM1 -8399.0
H3-3B -8363.0
WASF2 -8328.0
FAM169A -8320.0
NSL1 -8302.0
LRRC41 -8263.0
H3C8 -8260.0
H2BC3 -8237.0
CENPQ -8231.0
ARHGAP11A -8212.0
TMEM87A -8198.0
ARAP1 -8191.0
PPP1R14A -8110.0
H2BC8 -8108.0
NET1 -8107.0
GRB7 -8032.0
UBXN11 -8014.0
MSI2 -7990.0
GNA13 -7967.0
NCOA2 -7957.0
NDE1 -7893.0
STAM -7881.0
WHAMM -7838.0
KIF2C -7797.0
ZWINT -7770.0
NUDC -7747.0
HSP90AB1 -7735.0
RALBP1 -7727.0
H3C11 -7686.0
H2AZ1 -7538.0
PREX1 -7534.0
GFOD1 -7529.0
H2BC9 -7522.5
H3C7 -7522.5
NCF2 -7461.0
RND3 -7395.0
WIPF1 -7342.0
ACBD5 -7340.0
H2AJ -7338.0
ZWILCH -7287.0
ECT2 -7188.0
C1QBP -7162.0
PEAK1 -7155.0
RHOBTB3 -7136.0
DOCK9 -7123.0
ARHGAP29 -7117.0
MYO19 -7085.0
CUL3 -7084.0
FNBP1 -7052.0
KIF14 -7015.0
H2BC10 -6977.0
COPS4 -6973.0
BUB1B -6938.0
H3C3 -6933.0
TUBAL3 -6859.0
TUBA4A -6826.0
H3C12 -6825.0
SNAP23 -6823.0
NSFL1C -6819.0
BRK1 -6818.0
KIF5B -6805.0
CDKN1B -6757.0
H2AC8 -6733.0
CPD -6684.0
TMEM59 -6678.0
VRK2 -6642.0
ARHGAP30 -6606.0
ARHGAP5 -6572.0
PLD2 -6571.0
RAC3 -6570.0
DYNC1I2 -6523.0
H2AC18 -6516.5
H2AC19 -6516.5
TUBB3 -6481.0
SLK -6410.0
TUBA4B -6407.0
CLASP2 -6389.0
DOCK8 -6336.0
YWHAH -6318.0
PTK2B -6296.0
CDC42SE2 -6292.0
MYO9B -6250.0
SPC24 -6225.0
AKAP13 -6197.0
ARHGAP12 -6190.0
SLITRK5 -6186.0
YWHAZ -6164.0
KIF2B -6144.0
SEC13 -6136.0
H2BC14 -6126.0
BLTP3B -6101.0
PHIP -6088.0
TUBA1A -6069.0
SENP1 -6051.0
PLEKHG2 -6040.0
ARHGAP25 -6037.0
KDM4C -6032.0
FAM13A -5959.0
RHOU -5928.0
RHOT1 -5836.0
ROCK2 -5794.0
FRS3 -5722.0
PAFAH1B1 -5709.0
ITGB3BP -5665.0
ITSN2 -5658.0
ACTR2 -5655.0
CKAP4 -5628.0
CCDC88A -5604.0
RBBP6 -5551.0
MPP7 -5543.0
MFN1 -5510.0
FAM135A -5502.0
H3C2 -5478.0
PIK3CA -5472.0
PREX2 -5456.0
RHOA -5450.0
PGRMC2 -5423.0
FMNL1 -5405.0
TUBB2A -5397.0
ROCK1 -5392.0
SKA1 -5357.0
H2AC7 -5340.5
H2BC7 -5340.5
TAOK1 -5276.0
ARHGEF12 -5231.0
RAB7A -5134.0
SYDE1 -5112.0
ARHGAP26 -5109.0
MYL6 -5096.0
ARHGAP18 -5082.0
NDC80 -5070.0
ACTG1 -5045.0
GIT2 -5004.0
SOWAHC -4993.0
CCP110 -4990.0
SGO2 -4989.0
CENPC -4957.0
NISCH -4849.0
CFL1 -4824.0
ARHGEF18 -4743.0
ARHGAP35 -4710.0
VCP -4679.0
KNL1 -4647.0
ARFGAP3 -4646.0
TUBB6 -4561.0
PPP1R12A -4556.0
XPO1 -4530.0
MAPK14 -4437.0
SCAI -4419.0
STK10 -4389.0
MCAM -4368.0
TPM3 -4330.0
DYNC1H1 -4301.0
CENPP -4279.0
FAM13B -4250.0
GRB2 -4184.0
PKN3 -4151.0
FAM91A1 -4123.0
RCC2 -4121.0
PIK3R2 -4094.0
CENPT -4073.0
TMPO -4027.0
H4C4 -4007.0
NUP133 -3990.0
ITGB1 -3970.0
CCT6A -3936.0
TOR1AIP1 -3933.0
NDEL1 -3912.0
EPSTI1 -3902.0
TWF1 -3867.0
CENPO -3864.0
CKAP5 -3856.0
CPNE8 -3792.0
CIT -3779.0
H2BC21 -3732.0
CPSF7 -3727.0
VANGL2 -3679.0
DIAPH1 -3654.0
PPP2R5E -3635.0
TRAK2 -3610.0
FGD2 -3601.0
H4C6 -3568.0
RHPN1 -3533.0
ARPC3 -3530.0
LMAN1 -3525.0
KIF18A -3490.0
RPS27 -3484.0
RHOF -3411.0
PIN1 -3401.0
H2AC14 -3377.0
MFN2 -3335.0
ABI2 -3209.0
PRKCB -3201.0
TUBA1C -3186.0
ANKFY1 -3123.0
DSN1 -3120.0
SPTBN1 -3118.0
H3C4 -3045.0
ABR -3044.0
RND2 -2931.0
DBN1 -2919.0
NCK1 -2917.0
CLTC -2915.0
ARPC1B -2913.0
VIM -2911.0
HNRNPC -2910.0
PCDH7 -2909.0
OSBPL11 -2902.0
MRTFA -2901.0
VAMP3 -2881.0
AURKB -2861.0
RAP1GDS1 -2813.0
MYO9A -2729.0
SGO1 -2709.0
NUP98 -2703.0
PPP1R12B -2698.0
CENPL -2691.0
NCF4 -2678.0
EFHD2 -2656.0
PMF1 -2655.0
NCKAP1 -2620.0
HTR7 -2609.0
PLEKHG5 -2565.0
CLASP1 -2556.0
STIP1 -2550.0
PIK3R4 -2533.0
TUBA8 -2524.0
NUP160 -2508.0
INCENP -2499.0
PPP2CB -2471.0
PLEKHG4 -2457.0
VANGL1 -2372.0
PAK4 -2296.0
ARPC5 -2287.0
ACTR3 -2275.0
FLOT1 -2266.0
ARHGAP15 -2227.0
HSP90AA1 -2213.0
SPTAN1 -2199.0
LAMTOR1 -2197.0
SPC25 -2166.0
DYNC1I1 -2149.0
ARHGEF40 -2140.0
CENPE -2121.0
CEP97 -2120.0
AHCTF1 -2112.0
TUBB2B -2109.0
SRF -1998.0
VAV3 -1981.0
ADD3 -1980.0
B9D2 -1934.0
AMIGO2 -1909.0
IQGAP3 -1902.0
FRS2 -1809.0
DVL1 -1797.0
KLC1 -1763.0
NOX3 -1746.0
ARHGAP21 -1738.0
MYH14 -1698.0
CDC37 -1670.0
ARHGAP24 -1613.0
CAPZB -1568.0
BAIAP2L1 -1563.0
UACA -1552.0
PLK1 -1530.0
LIN7B -1485.0
CDC42BPA -1480.0
SAMM50 -1467.0
LMNB1 -1456.0
PKN1 -1423.0
ABL2 -1397.0
ARHGEF5 -1354.0
PPP2R5D -1303.0
DSG1 -1295.0
ARHGAP28 -1264.0
PRC1 -1191.0
KTN1 -1164.0
DLG4 -1151.0
H3C10 -1128.0
CCNE1 -1118.0
MACO1 -1099.0
FNBP1L -1097.0
ARHGEF3 -1094.0
H4C12 -1092.0
ARHGEF4 -1086.0
CCT2 -979.0
KDM1A -970.0
DIAPH3 -963.0
AAAS -910.0
WDR81 -891.0
RAC2 -876.0
PAK1 -872.0
H4C2 -859.0
NUP37 -825.0
CENPN -774.0
CENPM -681.0
RANGAP1 -663.0
TRIP10 -643.0
MEN1 -632.0
KLC2 -596.0
MIS12 -582.0
MYH10 -569.0
ABL1 -558.0
NUP43 -528.0
CKB -501.0
ACTB -471.0
PTPN13 -461.0
SPEN -420.0
ARHGEF1 -399.0
PRKCZ -386.0
TUBA3C -374.0
RHOBTB2 -351.0
ARAP2 -306.0
MAD1L1 -288.0
NDUFA5 -246.0
NF2 -142.0
RTKN -104.0
TUBA3E -95.0
KLC3 -70.0
SCFD1 -28.0
YWHAQ -11.0
H2BC13 1.0
BUB1 3.0
ABCD3 19.0
CTNNA1 39.0
RALGAPA1 71.0
ANKLE2 78.0
PLXND1 81.0
HMOX2 98.0
ARHGEF7 114.0
PAK2 116.0
EPHA2 118.0
IQGAP1 143.0
CYBA 145.0
KLC4 269.0
WIPF3 290.0
RAPGEF1 306.0
NUP85 327.0
RHOT2 333.0
MUC13 348.0
PARD6A 384.5
PPP2R5C 395.0
KIDINS220 440.0
PPP1CC 455.0
CENPH 476.0
RHOD 551.0
PKN2 568.0
CHN2 569.0
ARFGAP2 654.0
ALS2 667.0
CTTN 699.0
DEPDC1B 712.0
VHL 752.0
TAGAP 778.0
PDE5A 797.0
BUB3 813.0
YKT6 867.0
ARHGAP20 869.0
HSPE1 892.0
CHN1 906.0
ELMO2 918.0
MYO6 943.0
SHMT2 979.0
DOCK2 995.0
YWHAE 1068.0
ARHGAP31 1073.0
PDPK1 1090.0
TFRC 1092.0
ARPC4 1111.0
PKP4 1155.0
DOCK4 1179.0
NCKIPSD 1183.0
LRRC1 1187.0
CAV1 1218.0
RANBP2 1258.0
GOLGA3 1308.0
NUF2 1321.0
MAPRE1 1433.0
H4C8 1444.0
ARPC2 1448.0
DEF6 1477.0
ARHGEF2 1524.0
DAAM1 1580.0
CDH1 1603.0
H2BC26 1619.0
RHOC 1710.0
STAM2 1734.0
FLOT2 1735.0
YWHAB 1797.0
LEMD3 1803.0
PAK6 1862.0
MYH11 1902.0
RASAL2 1918.0
PPP2R5A 1963.0
SOS1 1990.0
PPP2R1B 2037.0
DVL2 2093.0
JAG1 2142.0
TNFAIP1 2169.0
ANLN 2188.0
H2BC15 2203.0
CTNNB1 2329.0
NUP107 2333.0
GMIP 2344.0
SKA2 2357.0
H2BC4 2363.0
NCK2 2370.0
PLEKHG6 2456.0
TJP2 2575.0
H4C1 2583.0
NIPSNAP2 2604.0
PPP2CA 2625.0
DYNC1LI2 2640.0
CDC42EP4 2644.0
SCRIB 2775.0
RASGRF2 2826.0
CENPS 2903.0
ERBIN 2913.0
CDC20 2914.0
ARHGAP1 2989.0
PRKCA 3022.0
ARHGAP17 3138.0
FERMT2 3148.0
WASF1 3177.0
H2AC20 3179.0
SOS2 3217.0
CYFIP2 3267.0
RHOBTB1 3280.0
DOCK5 3285.0
WWP2 3305.0
EMC3 3341.0
KLK2 3394.0
ITSN1 3422.0
SH3RF1 3446.0
ARHGDIB 3488.0
ARHGAP22 3499.0
AKAP12 3608.0
NGEF 3646.0
ARHGAP10 3647.0
FAM83B 3670.0
PTK2 3709.0
CENPU 3842.0
KIF2A 3843.0
SPDL1 3844.0
KNTC1 3867.0
PFN2 3948.0
ARHGAP33 3985.0
EVL 3986.0
TMOD3 4055.0
CENPF 4067.0
BASP1 4089.0
H2BC17 4130.0
MTR 4146.0
DBT 4242.0
ARHGAP42 4270.0
FMNL2 4308.0
VAPB 4343.0
STARD13 4378.0
DLC1 4393.0
SLC4A7 4410.0
MYH9 4460.0
TIAM1 4537.0
ARHGEF16 4579.0
NOXA1 4615.0
DSP 4643.0
H2BC11 4657.0
TUBA1B 4671.0
RRAS2 4720.0
H3C1 4735.0
SRRM1 4756.0
DST 4808.0
DDRGK1 4861.0
ARHGAP32 4897.0
PPP1CB 4911.0
FARP1 4915.0
PAK5 4945.0
PRAG1 5055.0
TRAK1 5075.0
FILIP1 5248.0
SRGAP3 5353.0
FARP2 5359.0
ABI1 5365.0
DOCK7 5390.0
H4C5 5401.0
ARHGEF19 5402.0
DDX4 5444.0
ARAP3 5468.0
H2AZ2 5485.0
CDC42EP5 5508.0
FAF2 5547.0
ARHGEF26 5559.0
TUBB1 5561.0
MCF2L 5631.0
STMN2 5632.0
SRC 5689.0
SPATA13 5729.0
KCTD3 5730.0
TIAM2 5739.0
DOCK10 5774.0
OBSCN 5781.0
ARHGAP8 5799.0
RND1 5892.0
CDC42BPB 5942.0
CCT7 5957.0
PLEKHG3 5962.0
CDC42EP1 5983.0
RHPN2 5987.0
RHOB 6006.0
ANKRD26 6016.0
ARHGAP39 6029.0
ARHGAP9 6082.0
FGD3 6083.0
ARHGAP19 6086.0
DOCK3 6129.0
ZW10 6165.0
ZAP70 6201.0
PPP2R1A 6221.0
RNF20 6279.0
TXNL1 6298.0
WDR11 6423.0
H2AC6 6426.0
CDC42EP2 6470.0
DNMBP 6477.0
RHOQ 6485.0
PLXNA1 6492.0
GOPC 6551.0
SEMA4F 6623.0
HGS 6652.0
RHOV 6732.0
H2AX 6737.0
BAIAP2 6744.0
DOCK1 6775.0
SH3PXD2A 6778.0
DVL3 6786.0
ARPC1A 6795.0
ACTN1 6836.0
HINT2 6904.0
ARHGAP45 6940.0
SRGAP2 6977.0
CCDC115 6990.0
TRIO 6998.0
FGD5 7018.0
ZNF512B 7042.0
DLG5 7054.0
ARHGEF10 7072.0
WASF3 7143.0
PIK3R3 7144.0
PLXNB1 7182.0
RHOJ 7195.0
MAD2L1 7226.0
CDCA8 7291.0
CENPK 7336.0
BIRC5 7359.0
ARL13B 7416.0
DOCK6 7435.0
ARHGEF25 7488.0
GPS1 7505.0
ARHGAP44 7625.0
ARHGEF28 7691.0
SRGAP1 7707.0
CYFIP1 7726.0
DSG2 7758.0
ALDH3A2 7795.0
ACTC1 7869.0
MAPK3 7947.0
CFTR 8023.0
ARHGAP40 8063.0
KIF5A 8065.0
ARHGDIG 8132.0
NOXO1 8200.0
WDR91 8297.0
BAIAP2L2 8317.0
FMNL3 8342.0
GARRE1 8361.0
ARHGEF11 8419.0
MYLK 8421.0
SEH1L 8440.0
PLEKHG1 8474.0
WIPF2 8508.0
LETM1 8631.0
KALRN 8651.0
JUP 8673.0
ARHGEF17 8719.0
VAV2 8721.0
MAPK11 8999.0
ARHGAP23 9075.0
DYNLL2 9125.0
PLEKHG4B 9293.0
ARHGEF10L 9747.0
KLK3 9821.0
ARHGEF15 9828.0
CSK 9857.0
PLIN3 9954.0
MYL9 9962.0
LCK 10052.0
SFN 10169.0
ARHGDIA 10469.0
STEAP3 10470.0
SH3BP1 10648.0
TUBB8 10871.0
IL32 10877.0
ROPN1 10918.0



REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH

REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH
1502
set REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH
setSize 96
pANOVA 6.49e-07
s.dist -0.294
p.adjustANOVA 3.13e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708
H3C6 -10650
SOD2 -10496
H4C3 -9942
H2BC12 -9581
H4C11 -9492
H4C9 -9486
H2BC5 -9371
DNMT3B -9346
H3-3A -9260
CDC25C -9256
H4C16 -9179
H2AC4 -9092
H2BC1 -8504
H4C13 -8401
H3-3B -8363
H3C8 -8260
H2BC3 -8237
CDC25A -8146
H2BC8 -8108

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
H3C6 -10650.0
SOD2 -10496.0
H4C3 -9942.0
H2BC12 -9581.0
H4C11 -9492.0
H4C9 -9486.0
H2BC5 -9371.0
DNMT3B -9346.0
H3-3A -9260.0
CDC25C -9256.0
H4C16 -9179.0
H2AC4 -9092.0
H2BC1 -8504.0
H4C13 -8401.0
H3-3B -8363.0
H3C8 -8260.0
H2BC3 -8237.0
CDC25A -8146.0
H2BC8 -8108.0
PRIM1 -7890.0
CDKN2A -7757.0
RIPK3 -7739.0
H3C11 -7686.0
EZH2 -7675.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
H2AJ -7338.0
C1QBP -7162.0
TRAF2 -7035.0
EED -7009.0
H2BC10 -6977.0
FOXO3 -6952.0
H3C3 -6933.0
H3C12 -6825.0
H2AC8 -6733.0
H2AC18 -6516.5
H2AC19 -6516.5
CAPN1 -6158.0
H2BC14 -6126.0
CAPNS1 -6102.0
H3C2 -5478.0
APP -5475.0
H2AC7 -5340.5
H2BC7 -5340.5
POLA2 -4771.0
CAST -4239.0
RIPK1 -4183.0
CASP8 -4047.0
H4C4 -4007.0
MLKL -3836.0
GOLGA2 -3802.0
H2BC21 -3732.0
CAPN2 -3589.0
H4C6 -3568.0
H2AC14 -3377.0
H3C4 -3045.0
BCL2L11 -2331.0
PRDX2 -2230.0
LMNB1 -1456.0
H3C10 -1128.0
H4C12 -1092.0
FADD -903.0
H4C2 -859.0
TP53 -831.0
FASLG -129.0
RBBP4 -33.0
H2BC13 1.0
PRDX1 13.0
CAPNS2 868.0
YWHAE 1068.0
H4C8 1444.0
DNMT3A 1573.0
H2BC26 1619.0
H2BC15 2203.0
H2BC4 2363.0
LMNA 2364.0
H4C1 2583.0
JUN 3045.0
H2AC20 3179.0
GSDME 3256.0
CDC25B 3854.0
H2BC17 4130.0
H2BC11 4657.0
PRIM2 4668.0
H3C1 4735.0
H4C5 5401.0
H2AZ2 5485.0
TRADD 5831.0
SUZ12 5843.0
H2AC6 6426.0
H2AX 6737.0
DNMT1 6745.0
CDK5 9357.0
CDK5R1 10081.0



REACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS

REACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS
1356
set REACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS
setSize 283
pANOVA 6.83e-07
s.dist -0.172
p.adjustANOVA 3.13e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
AREG -10981
CTSD -10727
H2BC6 -10708
H3C6 -10650
CXXC5 -10585
DHRS9 -10476
FKBP5 -10424
POLR2C -10372
EPGN -10353
MYB -10255
GNB5 -10046
SHC1 -10031
PDHB -9991
RARG -9989
RARA -9950
AGO4 -9949
H4C3 -9942
ALDH1A1 -9941
EP300 -9776
NR1H3 -9671

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AREG -10981.0
CTSD -10727.0
H2BC6 -10708.0
H3C6 -10650.0
CXXC5 -10585.0
DHRS9 -10476.0
FKBP5 -10424.0
POLR2C -10372.0
EPGN -10353.0
MYB -10255.0
GNB5 -10046.0
SHC1 -10031.0
PDHB -9991.0
RARG -9989.0
RARA -9950.0
AGO4 -9949.0
H4C3 -9942.0
ALDH1A1 -9941.0
EP300 -9776.0
NR1H3 -9671.0
APOC1 -9599.0
H2BC12 -9581.0
EREG -9500.0
H4C11 -9492.0
H4C9 -9486.0
PIK3R1 -9422.0
RUNX1 -9414.0
H2BC5 -9371.0
NRIP1 -9352.0
H3-3A -9260.0
H4C16 -9179.0
H2AC4 -9092.0
GATA3 -9064.0
KRAS -8798.0
RDH5 -8782.0
MAPK1 -8617.0
MED1 -8570.0
TGFA -8513.0
H2BC1 -8504.0
KAT2B -8472.0
NCOR2 -8471.0
H4C13 -8401.0
CALM1 -8399.0
H3-3B -8363.0
AXIN1 -8331.0
GTF2A2 -8284.0
H3C8 -8260.0
H2BC3 -8237.0
H2BC8 -8108.0
NRAS -7996.0
NCOA2 -7957.0
UHMK1 -7844.0
SREBF1 -7759.0
HSP90AB1 -7735.0
POLR2K -7697.0
H3C11 -7686.0
PRMT1 -7681.0
AGO3 -7679.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
ABCA1 -7494.0
TNRC6B -7491.0
FOSB -7478.0
GNB2 -7436.0
H2AJ -7338.0
FOXA1 -7309.0
POLR2A -7267.0
CDK9 -7238.0
H2BC10 -6977.0
USF2 -6961.0
FOXO3 -6952.0
H3C3 -6933.0
CBFB -6875.0
H3C12 -6825.0
CDKN1B -6757.0
H2AC8 -6733.0
GNG3 -6698.0
RXRA -6640.0
GNGT1 -6589.0
GTF2F1 -6537.0
H2AC18 -6516.5
H2AC19 -6516.5
GNG10 -6483.0
HBEGF -6448.0
GNAI3 -6294.0
CHD1 -6270.0
H2BC14 -6126.0
AGO1 -6050.0
PDHX -6017.0
SP1 -5960.0
PTGES3 -5864.0
POU2F1 -5859.0
PDHA2 -5622.0
HSPB1 -5590.0
H3C2 -5478.0
PIK3CA -5472.0
CRABP2 -5399.0
H2AC7 -5340.5
H2BC7 -5340.5
GNG11 -5292.0
RDH11 -5162.0
YY1 -5148.0
CPT1A -5111.0
PDK1 -5088.0
KAT5 -5079.0
KDM4B -4912.0
ABCG1 -4847.0
STRN -4804.0
GPAM -4680.0
RDH10 -4671.0
XPO1 -4530.0
MOV10 -4504.0
TNRC6C -4438.0
AKT1 -4393.0
GTF2A1 -4237.0
TBP -4230.0
PIK3R2 -4094.0
TBL1XR1 -4015.0
H4C4 -4007.0
KDM4A -3935.0
ADH1C -3863.0
GNG7 -3819.0
H2BC21 -3732.0
NCOA1 -3650.0
AKT3 -3595.0
H4C6 -3568.0
GNAI2 -3527.0
GNB1 -3520.0
RXRB -3388.0
H2AC14 -3377.0
ESR2 -3312.0
CYP26B1 -3175.0
STAG1 -3119.0
H3C4 -3045.0
RDH14 -2929.0
POLR2I -2893.0
DLD -2800.0
GPS2 -2644.0
DHRS3 -2631.0
GNB4 -2618.0
POLR2B -2615.0
FABP5 -2493.0
KANK1 -2443.0
GNG12 -2359.0
NCOA3 -2235.0
CYP26C1 -2223.0
HSP90AA1 -2213.0
GNG5 -2179.0
PLIN1 -2105.0
CAV2 -2091.0
MYC -2072.0
SRF -1998.0
NOS3 -1936.0
CYP26A1 -1928.0
USF1 -1841.0
PLTP -1837.0
RAD21 -1610.0
RDH13 -1602.0
JUND -1598.0
SMC3 -1334.0
POLR2G -1251.0
H3C10 -1128.0
HRAS -1109.0
H4C12 -1092.0
KDM1A -970.0
ALDH1A2 -920.0
H4C2 -859.0
NR5A2 -826.0
SPHK1 -631.0
PPARD -473.0
TLE3 -422.0
PRKCZ -386.0
GNG8 -148.0
H2BC13 1.0
CXCL12 64.0
ZDHHC7 133.0
MYLIP 151.0
ERBB4 296.0
BTC 301.0
CETP 505.0
GTF2F2 536.0
BCL2 594.0
FOS 612.0
ATF2 857.0
PDPK1 1090.0
CCND1 1122.0
CAV1 1218.0
MMP9 1241.0
H4C8 1444.0
KDM3A 1459.0
GNG2 1545.0
H2BC26 1619.0
MMP2 1631.0
PDK4 1645.0
ALDH1A3 1762.0
NCOR1 1776.0
POLR2L 1891.0
S1PR3 1911.0
TNRC6A 1957.0
AKR1C3 2000.0
AGO2 2114.0
H2BC15 2203.0
CREB1 2212.0
KCTD6 2338.0
H2BC4 2363.0
HDAC3 2573.0
H4C1 2583.0
FABP6 2627.0
FASN 2708.0
EGF 2787.0
EBAG9 2836.0
PPID 2905.0
SCD 2907.0
JUN 3045.0
POLR2H 3091.0
H2AC20 3179.0
DHRS4 3254.0
EEPD1 3273.0
PGR 3276.0
FKBP4 3431.0
GNAI1 3557.0
RARB 3559.0
POLR2F 3701.0
PTK2 3709.0
ADH4 3940.0
UGT1A3 4024.0
PPP5C 4025.0
H2BC17 4130.0
POLR2E 4421.0
DDX5 4449.0
H2BC11 4657.0
H3C1 4735.0
ESR1 4769.0
APOD 4878.0
HDAC1 4949.0
DLAT 5036.0
NR1H2 5134.0
GNAT3 5218.0
GNG4 5224.0
IGF1R 5272.0
RDH16 5342.0
H4C5 5401.0
H2AZ2 5485.0
MMP7 5597.0
SRC 5689.0
EGFR 5712.0
CREBBP 5734.0
AKT2 5824.0
APOE 5875.0
PDK2 6111.0
SDR16C5 6319.0
ARL4C 6337.0
H2AC6 6426.0
ZDHHC21 6460.0
H2AX 6737.0
ZNF217 6859.0
ANGPTL3 6929.0
CRABP1 7066.0
KPNA2 7126.0
PIK3R3 7144.0
CCNT1 7156.0
APOC2 7534.0
GREB1 7739.0
CARM1 7764.0
MAPK3 7947.0
RXRG 7954.0
GNG13 8027.0
POLR2D 8105.0
KDM1B 8241.0
ABCG5 8569.0
CPT1B 8570.0
ABCG8 8743.0
APOC4 8855.0
ALDH8A1 8925.0
GNB3 9683.0
PCK1 9703.0
MMP3 9780.0
TFF1 10134.0
POLR2J 10234.0
TFF3 10295.0
ADH1A 10460.0
GNGT2 10884.0



REACTOME_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS

REACTOME_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS
1583
set REACTOME_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS
setSize 188
pANOVA 6.85e-07
s.dist -0.21
p.adjustANOVA 3.13e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
PSMB7 -10578
SOD2 -10496
NLRP3 -10484
PRKCD -10313
GPX1 -10165
MAFG -9997
TALDO1 -9936
NFE2L2 -9875
CSNK2A1 -9812
EP300 -9776
CHD9 -9689
UBC -9558
PSMD5 -9539
GPX8 -9381
TXN -9118
GSTP1 -9087
BLVRB -9084
PRDX6 -8994
CSNK2A2 -8850
TKT -8827

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PSMB7 -10578
SOD2 -10496
NLRP3 -10484
PRKCD -10313
GPX1 -10165
MAFG -9997
TALDO1 -9936
NFE2L2 -9875
CSNK2A1 -9812
EP300 -9776
CHD9 -9689
UBC -9558
PSMD5 -9539
GPX8 -9381
TXN -9118
GSTP1 -9087
BLVRB -9084
PRDX6 -8994
CSNK2A2 -8850
TKT -8827
SESN2 -8751
NPLOC4 -8719
HM13 -8705
MED1 -8570
COX20 -8517
TXNIP -8480
NCOR2 -8471
ABCC1 -8329
PSME1 -8101
PSMA6 -7988
NCOA2 -7957
RBX1 -7781
CDKN2A -7757
MUL1 -7466
NCF2 -7461
BACH1 -7220
CUL3 -7084
ME1 -7006
CUL1 -6904
MAP1LC3B -6900
PRDX3 -6824
COX19 -6756
HBA2 -6670
DPP3 -6656
RXRA -6640
COX7A2L -6623
PGD -6602
GSR -6596
GPX7 -6575
SCO1 -6569
COX6A1 -6563
PSMD13 -6393
COX4I1 -6386
SCO2 -6325
PSMC6 -6219
GSTA3 -6183
PSME2 -6132
COX7C -6123
TACO1 -5949
GPX2 -5878
GSK3B -5572
MAFK -5528
UBXN7 -5421
SOD3 -5299
CDKN1A -5005
ERO1A -4880
IDH1 -4830
GPX3 -4768
VCP -4679
PSMB10 -4606
STAT3 -4580
GSTA1 -4558
NDUFA4 -4469
COX14 -4397
AKT1 -4393
PSMB2 -4344
TXNRD1 -4302
FBXL17 -4179
PSMD7 -4057
SURF1 -4018
TBL1XR1 -4015
BLVRA -3823
TGS1 -3798
PRDX5 -3772
NCOA1 -3650
AKT3 -3595
GPX5 -3577
PSMA7 -3416
CYCS -3407
SESN1 -3275
PSME3 -3245
SKP1 -3229
PALB2 -3191
CAT -2898
PSMC4 -2787
SQSTM1 -2777
NCF4 -2678
COX16 -2510
HBA1 -2430
PRDX2 -2230
CSNK2B -2185
SEM1 -2183
MYC -2072
PSMB6 -1996
PSMD14 -1965
COX6C -1852
GCLM -1832
LRPPRC -1749
PSMD9 -1453
SIN3A -1392
PSMC5 -1352
TXNRD2 -1218
PSMB4 -1200
TXN2 -1176
NOX4 -1035
PSMA3 -989
COX6B1 -915
PSMC2 -840
SKP2 -722
NCOA6 -707
PSMD6 -684
UFD1 -637
ATOX1 -617
PSMD11 -524
PSMB1 -483
COX18 -423
PSMA4 -398
PRDX1 13
PSMD4 55
COX11 91
HMOX2 98
P4HB 134
CYBA 145
PPARA 293
PSMD12 373
BRCA1 456
PSMF1 550
GCLC 576
PSMA2 776
PSMD3 1087
PSMB9 1093
UBB 1320
NQO1 1491
NCOR1 1776
PSMA5 1847
PSMB8 2004
BTRC 2163
PSMA1 2177
RPS27A 2313
COX5B 2447
HDAC3 2573
UBA52 2643
PSMD8 2754
KEAP1 2884
PSME4 3100
PSMD1 3155
NUDT2 3356
NOTCH1 3378
ATF4 3388
SIN3B 3728
ALB 4005
COX5A 4199
STAP2 4682
PSMC1 4758
PSMB3 5015
HMOX1 5202
SMARCD3 5277
PSMC3 5724
CREBBP 5734
PSMB5 5798
AKT2 5824
SOD1 5891
SRXN1 5955
COX8A 6060
CCS 6173
SLC7A11 6391
NOX5 6493
HELZ2 6711
PTK6 7450
CARM1 7764
GPX6 7883
FABP1 8263
PSMD2 8298
HBB 8442
PSMA8 8939
TRIM21 9666
AQP8 9729
PSMB11 10222



REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION
437
set REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION
setSize 138
pANOVA 8.49e-07
s.dist -0.243
p.adjustANOVA 3.77e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708
H3C6 -10650
ERCC3 -10242
H4C3 -9942
POLR1E -9865
EP300 -9776
SAP30BP -9662
H2BC12 -9581
H4C11 -9492
H4C9 -9486
JARID2 -9419
H2BC5 -9371
DNMT3B -9346
H3-3A -9260
H4C16 -9179
H2AC4 -9092
TAF1B -8949
DDX21 -8858
GATAD2B -8745
TET2 -8579

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
H3C6 -10650.0
ERCC3 -10242.0
H4C3 -9942.0
POLR1E -9865.0
EP300 -9776.0
SAP30BP -9662.0
H2BC12 -9581.0
H4C11 -9492.0
H4C9 -9486.0
JARID2 -9419.0
H2BC5 -9371.0
DNMT3B -9346.0
H3-3A -9260.0
H4C16 -9179.0
H2AC4 -9092.0
TAF1B -8949.0
DDX21 -8858.0
GATAD2B -8745.0
TET2 -8579.0
H2BC1 -8504.0
KAT2B -8472.0
H4C13 -8401.0
H3-3B -8363.0
H3C8 -8260.0
H2BC3 -8237.0
H2BC8 -8108.0
POLR2K -7697.0
H3C11 -7686.0
EZH2 -7675.0
SAP18 -7662.0
TTF1 -7591.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
H2AJ -7338.0
SAP30 -7138.0
EED -7009.0
H2BC10 -6977.0
H3C3 -6933.0
H3C12 -6825.0
H2AC8 -6733.0
H2AC18 -6516.5
H2AC19 -6516.5
UHRF1 -6494.0
SF3B1 -6304.0
H2BC14 -6126.0
CCNH -6119.0
MBD3 -5903.0
SUDS3 -5886.0
GSK3B -5572.0
HDAC2 -5534.0
H3C2 -5478.0
TAF1D -5430.0
MBD2 -5352.0
H2AC7 -5340.5
H2BC7 -5340.5
POLR1D -4579.0
GTF2H5 -4378.0
TBP -4230.0
H4C4 -4007.0
PHF19 -4003.0
BAZ1B -3837.0
H2BC21 -3732.0
GTF2H1 -3642.0
H4C6 -3568.0
H2AC14 -3377.0
SAP130 -3322.0
MNAT1 -3244.0
BAZ2A -3226.0
EHMT2 -3061.0
H3C4 -3045.0
MTA2 -2984.0
POLR1G -2833.0
GTF2H3 -2584.0
GATAD2A -2405.0
POLR1B -2231.0
POLR1F -2165.0
SMARCA5 -1620.0
SIN3A -1392.0
MTA1 -1189.0
H3C10 -1128.0
H4C12 -1092.0
PHF1 -1074.0
DEK -1023.0
H4C2 -859.0
MTF2 -564.0
ACTB -471.0
POLR1C -455.0
MYBBP1A -440.0
POLR1H -194.0
RBBP4 -33.0
H2BC13 1.0
TET1 169.0
CBX3 174.0
CHD3 338.0
ARID4B 1294.0
H4C8 1444.0
DNMT3A 1573.0
SAP30L 1574.0
H2BC26 1619.0
POLR1A 1793.0
DNMT3L 1842.0
CDK7 1850.0
POLR2L 1891.0
MYO1C 2134.0
H2BC15 2203.0
ERCC2 2323.0
H2BC4 2363.0
H4C1 2583.0
SIRT1 2715.0
RRP8 2770.0
AEBP2 3010.0
POLR2H 3091.0
H2AC20 3179.0
POLR2F 3701.0
SIN3B 3728.0
TAF1C 3808.0
KAT2A 3907.0
H2BC17 4130.0
TDG 4222.0
POLR2E 4421.0
H2BC11 4657.0
H3C1 4735.0
HDAC1 4949.0
TAF1A 4963.0
ERCC6 5141.0
H4C5 5401.0
H2AZ2 5485.0
TET3 5523.0
GTF2H4 5821.0
SUZ12 5843.0
CHD4 6248.0
H2AC6 6426.0
H2AX 6737.0
DNMT1 6745.0
UBTF 6820.0
MTA3 6867.0



REACTOME_HCMV_INFECTION

REACTOME_HCMV_INFECTION
1463
set REACTOME_HCMV_INFECTION
setSize 152
pANOVA 9.47e-07
s.dist -0.23
p.adjustANOVA 4.09e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708
H3C6 -10650
POM121C -10473
TUBA3D -10346
TUBB4B -10078
H4C3 -9942
H2BC12 -9581
H4C11 -9492
DYNLL1 -9489
H4C9 -9486
DYNC1LI1 -9445
H2BC5 -9371
H2AC16 -9348
H4C16 -9179
H2AC4 -9092
RAE1 -9026
TUBB4A -8809
CHMP4A -8725
H2BC1 -8504
NCOR2 -8471

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
H3C6 -10650.0
POM121C -10473.0
TUBA3D -10346.0
TUBB4B -10078.0
H4C3 -9942.0
H2BC12 -9581.0
H4C11 -9492.0
DYNLL1 -9489.0
H4C9 -9486.0
DYNC1LI1 -9445.0
H2BC5 -9371.0
H2AC16 -9348.0
H4C16 -9179.0
H2AC4 -9092.0
RAE1 -9026.0
TUBB4A -8809.0
CHMP4A -8725.0
H2BC1 -8504.0
NCOR2 -8471.0
H4C13 -8401.0
H3C8 -8260.0
H2BC3 -8237.0
VPS37C -8205.0
H2BC8 -8108.0
NUP50 -7820.0
H3C11 -7686.0
EZH2 -7675.0
NUP93 -7632.0
H2BC9 -7522.5
H3C7 -7522.5
H2AC21 -7374.0
CHMP2B -7324.0
EED -7009.0
H2BC10 -6977.0
H3C3 -6933.0
TSG101 -6877.0
TUBAL3 -6859.0
TUBA4A -6826.0
H3C12 -6825.0
PML -6800.0
H2AC8 -6733.0
DYNC1I2 -6523.0
H2AC18 -6516.5
H2AC19 -6516.5
TUBB3 -6481.0
TUBA4B -6407.0
H2AC1 -6275.0
VPS36 -6155.0
SEC13 -6136.0
H2BC14 -6126.0
TUBA1A -6069.0
NUP155 -5935.0
H3C2 -5478.0
TUBB2A -5397.0
H2AC7 -5340.5
H2BC7 -5340.5
NUP153 -5310.0
POM121 -5300.0
TRIM28 -5298.0
VPS28 -5222.0
H2AC12 -5204.0
CHMP6 -5085.0
VPS37A -4694.0
TUBB6 -4561.0
DYNC1H1 -4301.0
NUP188 -4141.0
TBL1XR1 -4015.0
H4C4 -4007.0
NUP133 -3990.0
ITGB1 -3970.0
CHMP2A -3860.0
H2BC21 -3732.0
MVB12A -3624.0
H4C6 -3568.0
H2AC14 -3377.0
TUBA1C -3186.0
NUP42 -3160.0
UBAP1 -3098.0
H3C4 -3045.0
NUP98 -2703.0
GPS2 -2644.0
TUBA8 -2524.0
NUP160 -2508.0
CHMP4C -2173.0
DYNC1I1 -2149.0
TUBB2B -2109.0
NUP35 -2059.0
CHMP3 -2000.0
H3C10 -1128.0
H4C12 -1092.0
AAAS -910.0
H4C2 -859.0
NUP37 -825.0
CEBPD -678.0
NUP43 -528.0
NUP214 -489.0
TUBA3C -374.0
NFKB1 -285.0
H2AC17 -112.0
TUBA3E -95.0
RBBP4 -33.0
SNF8 -25.0
H2BC13 1.0
H2AC25 146.0
CHMP1A 196.0
NUP85 327.0
CBX1 812.0
NUP54 1027.0
DAXX 1201.0
RANBP2 1258.0
VPS37B 1367.0
H4C8 1444.0
H2BC26 1619.0
NUP88 1774.0
NCOR1 1776.0
CHMP7 1896.0
H2AC15 1986.0
NUP210 2136.0
H2BC15 2203.0
CREB1 2212.0
HNRNPK 2304.0
NUP107 2333.0
H2BC4 2363.0
NDC1 2461.0
HDAC3 2573.0
H4C1 2583.0
DYNC1LI2 2640.0
VPS4A 2877.0
VPS37D 2948.0
H2AC20 3179.0
MVB12B 3703.0
H2BC17 4130.0
NUP58 4456.0
H2BC11 4657.0
TUBA1B 4671.0
H3C1 4735.0
H4C5 5401.0
TUBB1 5561.0
EGFR 5712.0
SUZ12 5843.0
CHMP4B 5954.0
H2AC6 6426.0
NUP205 6912.0
TPR 7154.0
VPS25 7242.0
NUP62 7697.0
SEH1L 8440.0
H2AC13 8584.0
DYNLL2 9125.0
H2AC11 9249.0
TUBB8 10871.0



REACTOME_CELL_CYCLE_CHECKPOINTS

REACTOME_CELL_CYCLE_CHECKPOINTS
1120
set REACTOME_CELL_CYCLE_CHECKPOINTS
setSize 284
pANOVA 1.1e-06
s.dist -0.168
p.adjustANOVA 4.65e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708
PSMB7 -10578
RMI2 -10267
YWHAG -10207
H4C3 -9942
CCNE2 -9681
H2BC12 -9581
BLM -9563
UBC -9558
PSMD5 -9539
NBN -9502
H4C11 -9492
DYNLL1 -9489
H4C9 -9486
DYNC1LI1 -9445
H2BC5 -9371
CDC25C -9256
H4C16 -9179
CHEK1 -9151
UBE2E1 -9071

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
PSMB7 -10578.0
RMI2 -10267.0
YWHAG -10207.0
H4C3 -9942.0
CCNE2 -9681.0
H2BC12 -9581.0
BLM -9563.0
UBC -9558.0
PSMD5 -9539.0
NBN -9502.0
H4C11 -9492.0
DYNLL1 -9489.0
H4C9 -9486.0
DYNC1LI1 -9445.0
H2BC5 -9371.0
CDC25C -9256.0
H4C16 -9179.0
CHEK1 -9151.0
UBE2E1 -9071.0
CLIP1 -8978.0
HUS1 -8871.0
CENPA -8800.0
CDC16 -8598.0
H2BC1 -8504.0
PPP2R5B -8503.0
H4C13 -8401.0
NSL1 -8302.0
H2BC3 -8237.0
CENPQ -8231.0
CDC25A -8146.0
H2BC8 -8108.0
PSME1 -8101.0
RAD1 -8063.0
CDK2 -8046.0
PHF20 -8020.0
PSMA6 -7988.0
NDE1 -7893.0
KIF2C -7797.0
ZWINT -7770.0
CCNB2 -7768.0
CDKN2A -7757.0
NUDC -7747.0
H2BC9 -7522.5
ATRIP -7316.0
ZWILCH -7287.0
H2BC10 -6977.0
BUB1B -6938.0
ORC2 -6761.0
CDKN1B -6757.0
DYNC1I2 -6523.0
PSMD13 -6393.0
CLASP2 -6389.0
YWHAH -6318.0
SPC24 -6225.0
PSMC6 -6219.0
YWHAZ -6164.0
KIF2B -6144.0
SEC13 -6136.0
PSME2 -6132.0
H2BC14 -6126.0
CDC26 -6099.0
ANAPC10 -6095.0
ANAPC7 -5877.0
BARD1 -5779.0
PAFAH1B1 -5709.0
MRE11 -5675.0
ITGB3BP -5665.0
RNF8 -5619.0
ATM -5608.0
RBBP8 -5574.0
SKA1 -5357.0
H2BC7 -5340.5
TAOK1 -5276.0
CHEK2 -5211.0
KAT5 -5079.0
NDC80 -5070.0
CDKN1A -5005.0
SGO2 -4989.0
BABAM2 -4972.0
COP1 -4967.0
CENPC -4957.0
ATR -4921.0
ORC3 -4904.0
ABRAXAS1 -4723.0
KNL1 -4647.0
PSMB10 -4606.0
XPO1 -4530.0
PSMB2 -4344.0
DYNC1H1 -4301.0
CENPP -4279.0
CDC23 -4153.0
RCC2 -4121.0
CENPT -4073.0
PSMD7 -4057.0
CDC27 -4025.0
H4C4 -4007.0
NUP133 -3990.0
NDEL1 -3912.0
MCM3 -3901.0
CENPO -3864.0
CKAP5 -3856.0
RFC5 -3853.0
H2BC21 -3732.0
PPP2R5E -3635.0
NSD2 -3599.0
H4C6 -3568.0
KIF18A -3490.0
RPS27 -3484.0
UBE2N -3431.0
PSMA7 -3416.0
DBF4 -3290.0
PSME3 -3245.0
MCM8 -3130.0
DSN1 -3120.0
TP53BP1 -3116.0
CDC45 -2877.0
RFC4 -2868.0
AURKB -2861.0
RFC3 -2823.0
PSMC4 -2787.0
CDK1 -2730.0
CCNA1 -2724.0
SGO1 -2709.0
NUP98 -2703.0
CENPL -2691.0
PMF1 -2655.0
CLASP1 -2556.0
NUP160 -2508.0
INCENP -2499.0
PPP2CB -2471.0
ORC4 -2389.0
MCM2 -2330.0
UIMC1 -2261.0
SEM1 -2183.0
SPC25 -2166.0
DYNC1I1 -2149.0
CENPE -2121.0
AHCTF1 -2112.0
ORC1 -2097.0
ANAPC5 -2079.0
RAD17 -2076.0
PSMB6 -1996.0
CDC6 -1968.0
PSMD14 -1965.0
B9D2 -1934.0
MCM5 -1856.0
BABAM1 -1800.0
PLK1 -1530.0
PSMD9 -1453.0
EXO1 -1398.0
PSMC5 -1352.0
PPP2R5D -1303.0
PSMB4 -1200.0
CCNE1 -1118.0
RMI1 -1101.0
H4C12 -1092.0
MDM2 -1085.0
RHNO1 -1080.0
RAD9B -1016.0
PSMA3 -989.0
H4C2 -859.0
PSMC2 -840.0
TP53 -831.0
NUP37 -825.0
CENPN -774.0
UBE2C -706.0
PSMD6 -684.0
CENPM -681.0
RANGAP1 -663.0
MIS12 -582.0
PIAS4 -575.0
NUP43 -528.0
PSMD11 -524.0
ANAPC15 -493.0
RAD9A -486.0
PSMB1 -483.0
MCM4 -452.0
PSMA4 -398.0
MAD1L1 -288.0
PCBP4 -174.0
MDM4 -86.0
WEE1 -40.0
YWHAQ -11.0
H2BC13 1.0
BUB1 3.0
UBE2S 7.0
CDC7 20.0
PSMD4 55.0
ORC5 201.0
NUP85 327.0
PSMD12 373.0
PPP2R5C 395.0
PPP1CC 455.0
BRCA1 456.0
CENPH 476.0
PSMF1 550.0
PSMA2 776.0
BUB3 813.0
H3-4 835.0
ANAPC11 853.0
YWHAE 1068.0
PSMD3 1087.0
PSMB9 1093.0
ANAPC4 1161.0
MDC1 1223.0
ORC6 1225.0
RANBP2 1258.0
UBB 1320.0
NUF2 1321.0
MAPRE1 1433.0
H4C8 1444.0
HERC2 1503.0
WRN 1553.0
RPA2 1570.0
H2BC26 1619.0
YWHAB 1797.0
PSMA5 1847.0
UBE2V2 1929.0
PPP2R5A 1963.0
PSMB8 2004.0
MCM6 2022.0
PPP2R1B 2037.0
PSMA1 2177.0
ANAPC16 2196.0
H2BC15 2203.0
RPS27A 2313.0
NUP107 2333.0
SKA2 2357.0
H2BC4 2363.0
H4C1 2583.0
BRIP1 2607.0
PPP2CA 2625.0
DYNC1LI2 2640.0
UBA52 2643.0
PSMD8 2754.0
DNA2 2831.0
CENPS 2903.0
CDC20 2914.0
RFC2 2936.0
PSME4 3100.0
PSMD1 3155.0
CCNB1 3317.0
ZNF385A 3333.0
MCM7 3530.0
GTSE1 3631.0
MCM10 3811.0
CENPU 3842.0
KIF2A 3843.0
SPDL1 3844.0
KNTC1 3867.0
CENPF 4067.0
H2BC17 4130.0
ANAPC1 4318.0
RNF168 4485.0
ANAPC2 4548.0
H2BC11 4657.0
RPA3 4736.0
TOPBP1 4738.0
PSMC1 4758.0
PSMB3 5015.0
PKMYT1 5191.0
CCNA2 5235.0
H4C5 5401.0
PSMC3 5724.0
PSMB5 5798.0
TOP3A 5902.0
ZW10 6165.0
PPP2R1A 6221.0
RAD50 6618.0
H2AX 6737.0
UBE2D1 7063.0
RPA1 7064.0
MAD2L1 7226.0
CDCA8 7291.0
CENPK 7336.0
BIRC5 7359.0
CLSPN 7366.0
PSMD2 8298.0
SEH1L 8440.0
PSMA8 8939.0
DYNLL2 9125.0
SFN 10169.0
PSMB11 10222.0



REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES

REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES
480
set REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES
setSize 66
pANOVA 1.16e-06
s.dist -0.346
p.adjustANOVA 4.75e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708
H3C6 -10650
H4C3 -9942
SMC2 -9640
H2BC12 -9581
H4C11 -9492
H4C9 -9486
H2BC5 -9371
H3-3A -9260
H4C16 -9179
H2AC4 -9092
KMT5A -9054
RB1 -8767
H2BC1 -8504
H4C13 -8401
H3-3B -8363
H3C8 -8260
H2BC3 -8237
H2BC8 -8108
H3C11 -7686

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
H3C6 -10650.0
H4C3 -9942.0
SMC2 -9640.0
H2BC12 -9581.0
H4C11 -9492.0
H4C9 -9486.0
H2BC5 -9371.0
H3-3A -9260.0
H4C16 -9179.0
H2AC4 -9092.0
KMT5A -9054.0
RB1 -8767.0
H2BC1 -8504.0
H4C13 -8401.0
H3-3B -8363.0
H3C8 -8260.0
H2BC3 -8237.0
H2BC8 -8108.0
H3C11 -7686.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
H2AJ -7338.0
H2BC10 -6977.0
H3C3 -6933.0
H3C12 -6825.0
H2AC8 -6733.0
H2AC18 -6516.5
H2AC19 -6516.5
MCPH1 -6206.0
H2BC14 -6126.0
SMC4 -5947.0
H3C2 -5478.0
H2AC7 -5340.5
H2BC7 -5340.5
NCAPG2 -4222.0
H4C4 -4007.0
H2BC21 -3732.0
H4C6 -3568.0
H2AC14 -3377.0
H3C4 -3045.0
CDK1 -2730.0
PLK1 -1530.0
H3C10 -1128.0
H4C12 -1092.0
H4C2 -859.0
SET -625.0
H2BC13 1.0
H3-4 835.0
H4C8 1444.0
H2BC26 1619.0
H2BC15 2203.0
H2BC4 2363.0
H4C1 2583.0
NCAPD3 2979.0
H2AC20 3179.0
CCNB1 3317.0
H2BC17 4130.0
H2BC11 4657.0
H3C1 4735.0
H4C5 5401.0
H2AZ2 5485.0
H2AC6 6426.0
H2AX 6737.0
NCAPH2 7983.0



REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS

REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS
1282
set REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS
setSize 121
pANOVA 1.19e-06
s.dist -0.256
p.adjustANOVA 4.77e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
SPI1 -10725
H2BC6 -10708
H3C6 -10650
PSMB7 -10578
GATA2 -10464
MYB -10255
H4C3 -9942
LMO2 -9851
H2BC12 -9581
UBC -9558
PSMD5 -9539
TAL1 -9534
H4C11 -9492
H4C9 -9486
RUNX1 -9414
H2BC5 -9371
H3-3A -9260
H4C16 -9179
H2AC4 -9092
GATA3 -9064

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SPI1 -10725.0
H2BC6 -10708.0
H3C6 -10650.0
PSMB7 -10578.0
GATA2 -10464.0
MYB -10255.0
H4C3 -9942.0
LMO2 -9851.0
H2BC12 -9581.0
UBC -9558.0
PSMD5 -9539.0
TAL1 -9534.0
H4C11 -9492.0
H4C9 -9486.0
RUNX1 -9414.0
H2BC5 -9371.0
H3-3A -9260.0
H4C16 -9179.0
H2AC4 -9092.0
GATA3 -9064.0
H2BC1 -8504.0
LDB1 -8418.0
H4C13 -8401.0
H3-3B -8363.0
H3C8 -8260.0
H2BC3 -8237.0
H2BC8 -8108.0
PSME1 -8101.0
PSMA6 -7988.0
H3C11 -7686.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
H2AJ -7338.0
TCF12 -7186.0
H2BC10 -6977.0
H3C3 -6933.0
CBFB -6875.0
H3C12 -6825.0
H2AC8 -6733.0
H2AC18 -6516.5
H2AC19 -6516.5
PSMD13 -6393.0
PSMC6 -6219.0
PSME2 -6132.0
H2BC14 -6126.0
CCNH -6119.0
H3C2 -5478.0
H2AC7 -5340.5
H2BC7 -5340.5
PSMB10 -4606.0
PSMB2 -4344.0
PSMD7 -4057.0
H4C4 -4007.0
H2BC21 -3732.0
H4C6 -3568.0
PSMA7 -3416.0
H2AC14 -3377.0
PSME3 -3245.0
MNAT1 -3244.0
ITCH -3210.0
H3C4 -3045.0
PSMC4 -2787.0
SEM1 -2183.0
PSMB6 -1996.0
PSMD14 -1965.0
PSMD9 -1453.0
PSMC5 -1352.0
PSMB4 -1200.0
KMT2A -1135.0
H3C10 -1128.0
H4C12 -1092.0
PSMA3 -989.0
H4C2 -859.0
PSMC2 -840.0
PSMD6 -684.0
ABL1 -558.0
PSMD11 -524.0
PSMB1 -483.0
PSMA4 -398.0
H2BC13 1.0
PSMD4 55.0
TCF3 67.0
PSMD12 373.0
PSMF1 550.0
PSMA2 776.0
PSMD3 1087.0
PSMB9 1093.0
LMO1 1210.0
UBB 1320.0
H4C8 1444.0
H2BC26 1619.0
PSMA5 1847.0
CDK7 1850.0
PSMB8 2004.0
PSMA1 2177.0
H2BC15 2203.0
RPS27A 2313.0
H2BC4 2363.0
H4C1 2583.0
UBA52 2643.0
PSMD8 2754.0
PSME4 3100.0
PSMD1 3155.0
H2AC20 3179.0
YAP1 4098.0
H2BC17 4130.0
TP73 4436.0
H2BC11 4657.0
H3C1 4735.0
PSMC1 4758.0
PSMB3 5015.0
H4C5 5401.0
H2AZ2 5485.0
PSMC3 5724.0
PSMB5 5798.0
H2AC6 6426.0
H2AX 6737.0
PSMD2 8298.0
PSMA8 8939.0
PSMB11 10222.0



REACTOME_HCMV_EARLY_EVENTS

REACTOME_HCMV_EARLY_EVENTS
1464
set REACTOME_HCMV_EARLY_EVENTS
setSize 128
pANOVA 1.66e-06
s.dist -0.245
p.adjustANOVA 6.49e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708
H3C6 -10650
POM121C -10473
TUBA3D -10346
TUBB4B -10078
H4C3 -9942
H2BC12 -9581
H4C11 -9492
DYNLL1 -9489
H4C9 -9486
DYNC1LI1 -9445
H2BC5 -9371
H2AC16 -9348
H4C16 -9179
H2AC4 -9092
RAE1 -9026
TUBB4A -8809
H2BC1 -8504
NCOR2 -8471
H4C13 -8401

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
H3C6 -10650.0
POM121C -10473.0
TUBA3D -10346.0
TUBB4B -10078.0
H4C3 -9942.0
H2BC12 -9581.0
H4C11 -9492.0
DYNLL1 -9489.0
H4C9 -9486.0
DYNC1LI1 -9445.0
H2BC5 -9371.0
H2AC16 -9348.0
H4C16 -9179.0
H2AC4 -9092.0
RAE1 -9026.0
TUBB4A -8809.0
H2BC1 -8504.0
NCOR2 -8471.0
H4C13 -8401.0
H3C8 -8260.0
H2BC3 -8237.0
H2BC8 -8108.0
NUP50 -7820.0
H3C11 -7686.0
EZH2 -7675.0
NUP93 -7632.0
H2BC9 -7522.5
H3C7 -7522.5
H2AC21 -7374.0
EED -7009.0
H2BC10 -6977.0
H3C3 -6933.0
TUBAL3 -6859.0
TUBA4A -6826.0
H3C12 -6825.0
PML -6800.0
H2AC8 -6733.0
DYNC1I2 -6523.0
H2AC18 -6516.5
H2AC19 -6516.5
TUBB3 -6481.0
TUBA4B -6407.0
H2AC1 -6275.0
SEC13 -6136.0
H2BC14 -6126.0
TUBA1A -6069.0
NUP155 -5935.0
H3C2 -5478.0
TUBB2A -5397.0
H2AC7 -5340.5
H2BC7 -5340.5
NUP153 -5310.0
POM121 -5300.0
TRIM28 -5298.0
H2AC12 -5204.0
TUBB6 -4561.0
DYNC1H1 -4301.0
NUP188 -4141.0
TBL1XR1 -4015.0
H4C4 -4007.0
NUP133 -3990.0
ITGB1 -3970.0
H2BC21 -3732.0
H4C6 -3568.0
H2AC14 -3377.0
TUBA1C -3186.0
NUP42 -3160.0
H3C4 -3045.0
NUP98 -2703.0
GPS2 -2644.0
TUBA8 -2524.0
NUP160 -2508.0
DYNC1I1 -2149.0
TUBB2B -2109.0
NUP35 -2059.0
H3C10 -1128.0
H4C12 -1092.0
AAAS -910.0
H4C2 -859.0
NUP37 -825.0
NUP43 -528.0
NUP214 -489.0
TUBA3C -374.0
NFKB1 -285.0
H2AC17 -112.0
TUBA3E -95.0
RBBP4 -33.0
H2BC13 1.0
H2AC25 146.0
NUP85 327.0
CBX1 812.0
NUP54 1027.0
DAXX 1201.0
RANBP2 1258.0
H4C8 1444.0
H2BC26 1619.0
NUP88 1774.0
NCOR1 1776.0
H2AC15 1986.0
NUP210 2136.0
H2BC15 2203.0
CREB1 2212.0
NUP107 2333.0
H2BC4 2363.0
NDC1 2461.0
HDAC3 2573.0
H4C1 2583.0
DYNC1LI2 2640.0
H2AC20 3179.0
H2BC17 4130.0
NUP58 4456.0
H2BC11 4657.0
TUBA1B 4671.0
H3C1 4735.0
H4C5 5401.0
TUBB1 5561.0
EGFR 5712.0
SUZ12 5843.0
H2AC6 6426.0
NUP205 6912.0
TPR 7154.0
NUP62 7697.0
SEH1L 8440.0
H2AC13 8584.0
DYNLL2 9125.0
H2AC11 9249.0
TUBB8 10871.0



REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION

REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION
1091
set REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION
setSize 62
pANOVA 1.72e-06
s.dist -0.351
p.adjustANOVA 6.57e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708.0
H3C6 -10650.0
H4C3 -9942.0
H2BC12 -9581.0
H4C11 -9492.0
H4C9 -9486.0
H2BC5 -9371.0
H3-3A -9260.0
H4C16 -9179.0
H2AC4 -9092.0
H2BC1 -8504.0
H4C13 -8401.0
H3-3B -8363.0
KPNA1 -8349.0
H3C8 -8260.0
H2BC3 -8237.0
H2BC8 -8108.0
H3C11 -7686.0
H2AZ1 -7538.0
H2BC9 -7522.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
H3C6 -10650.0
H4C3 -9942.0
H2BC12 -9581.0
H4C11 -9492.0
H4C9 -9486.0
H2BC5 -9371.0
H3-3A -9260.0
H4C16 -9179.0
H2AC4 -9092.0
H2BC1 -8504.0
H4C13 -8401.0
H3-3B -8363.0
KPNA1 -8349.0
H3C8 -8260.0
H2BC3 -8237.0
H2BC8 -8108.0
H3C11 -7686.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
H2AJ -7338.0
H2BC10 -6977.0
H3C3 -6933.0
H3C12 -6825.0
ORC2 -6761.0
H2AC8 -6733.0
H2AC18 -6516.5
H2AC19 -6516.5
H2BC14 -6126.0
H3C2 -5478.0
H2AC7 -5340.5
H2BC7 -5340.5
ORC3 -4904.0
H4C4 -4007.0
H2BC21 -3732.0
H4C6 -3568.0
H2AC14 -3377.0
H3C4 -3045.0
ORC4 -2389.0
ORC1 -2097.0
H3C10 -1128.0
H4C12 -1092.0
H4C2 -859.0
H2BC13 1.0
ORC5 201.0
KPNB1 488.0
KPNA6 605.0
ORC6 1225.0
H4C8 1444.0
H2BC26 1619.0
H2BC15 2203.0
H2BC4 2363.0
H4C1 2583.0
H2AC20 3179.0
H2BC17 4130.0
H2BC11 4657.0
H3C1 4735.0
H4C5 5401.0
H2AZ2 5485.0
H2AC6 6426.0
H2AX 6737.0



REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION

REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION
852
set REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION
setSize 84
pANOVA 1.85e-06
s.dist -0.301
p.adjustANOVA 6.9e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708
H3C6 -10650
H4C3 -9942
POLR1E -9865
EP300 -9776
H2BC12 -9581
H4C11 -9492
H4C9 -9486
H2BC5 -9371
H3-3A -9260
H4C16 -9179
H2AC4 -9092
TAF1B -8949
DDX21 -8858
H2BC1 -8504
KAT2B -8472
H4C13 -8401
H3-3B -8363
H3C8 -8260
H2BC3 -8237

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
H3C6 -10650.0
H4C3 -9942.0
POLR1E -9865.0
EP300 -9776.0
H2BC12 -9581.0
H4C11 -9492.0
H4C9 -9486.0
H2BC5 -9371.0
H3-3A -9260.0
H4C16 -9179.0
H2AC4 -9092.0
TAF1B -8949.0
DDX21 -8858.0
H2BC1 -8504.0
KAT2B -8472.0
H4C13 -8401.0
H3-3B -8363.0
H3C8 -8260.0
H2BC3 -8237.0
H2BC8 -8108.0
POLR2K -7697.0
H3C11 -7686.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
H2AJ -7338.0
H2BC10 -6977.0
H3C3 -6933.0
H3C12 -6825.0
H2AC8 -6733.0
H2AC18 -6516.5
H2AC19 -6516.5
SF3B1 -6304.0
H2BC14 -6126.0
GSK3B -5572.0
H3C2 -5478.0
TAF1D -5430.0
H2AC7 -5340.5
H2BC7 -5340.5
POLR1D -4579.0
TBP -4230.0
H4C4 -4007.0
BAZ1B -3837.0
H2BC21 -3732.0
H4C6 -3568.0
H2AC14 -3377.0
H3C4 -3045.0
POLR1G -2833.0
POLR1B -2231.0
POLR1F -2165.0
SMARCA5 -1620.0
H3C10 -1128.0
H4C12 -1092.0
DEK -1023.0
H4C2 -859.0
ACTB -471.0
POLR1C -455.0
MYBBP1A -440.0
POLR1H -194.0
H2BC13 1.0
H4C8 1444.0
H2BC26 1619.0
POLR1A 1793.0
POLR2L 1891.0
MYO1C 2134.0
H2BC15 2203.0
H2BC4 2363.0
H4C1 2583.0
POLR2H 3091.0
H2AC20 3179.0
POLR2F 3701.0
TAF1C 3808.0
KAT2A 3907.0
H2BC17 4130.0
POLR2E 4421.0
H2BC11 4657.0
H3C1 4735.0
TAF1A 4963.0
ERCC6 5141.0
H4C5 5401.0
H2AZ2 5485.0
H2AC6 6426.0
H2AX 6737.0



REACTOME_MEIOTIC_RECOMBINATION

REACTOME_MEIOTIC_RECOMBINATION
1433
set REACTOME_MEIOTIC_RECOMBINATION
setSize 80
pANOVA 2.13e-06
s.dist -0.307
p.adjustANOVA 7.77e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708
H3C6 -10650
BRCA2 -10235
H4C3 -9942
H2BC12 -9581
BLM -9563
NBN -9502
H4C11 -9492
H4C9 -9486
H2BC5 -9371
H3-3A -9260
H4C16 -9179
H2AC4 -9092
H2BC1 -8504
H4C13 -8401
H3-3B -8363
H3C8 -8260
H2BC3 -8237
H2BC8 -8108
CDK2 -8046

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
H3C6 -10650.0
BRCA2 -10235.0
H4C3 -9942.0
H2BC12 -9581.0
BLM -9563.0
NBN -9502.0
H4C11 -9492.0
H4C9 -9486.0
H2BC5 -9371.0
H3-3A -9260.0
H4C16 -9179.0
H2AC4 -9092.0
H2BC1 -8504.0
H4C13 -8401.0
H3-3B -8363.0
H3C8 -8260.0
H2BC3 -8237.0
H2BC8 -8108.0
CDK2 -8046.0
H3C11 -7686.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
H2AJ -7338.0
H2BC10 -6977.0
H3C3 -6933.0
H3C12 -6825.0
H2AC8 -6733.0
PSMC3IP -6654.0
H2AC18 -6516.5
H2AC19 -6516.5
H2BC14 -6126.0
SPO11 -5978.0
MLH3 -5957.0
MRE11 -5675.0
ATM -5608.0
RBBP8 -5574.0
H3C2 -5478.0
H2AC7 -5340.5
H2BC7 -5340.5
CDK4 -5202.0
MND1 -4729.0
H4C4 -4007.0
MSH4 -3914.0
H2BC21 -3732.0
H4C6 -3568.0
H2AC14 -3377.0
RAD51 -3266.0
H3C4 -3045.0
PRDM9 -1927.0
MSH5 -1775.0
H3C10 -1128.0
H4C12 -1092.0
DMC1 -929.0
H4C2 -859.0
MLH1 -367.0
H2BC13 1.0
BRCA1 456.0
H3-4 835.0
H4C8 1444.0
RPA2 1570.0
H2BC26 1619.0
H2BC15 2203.0
H2BC4 2363.0
H4C1 2583.0
H2AC20 3179.0
H2BC17 4130.0
H2BC11 4657.0
H3C1 4735.0
RPA3 4736.0
H4C5 5401.0
H2AZ2 5485.0
RAD51C 5512.0
TOP3A 5902.0
H2AC6 6426.0
RAD50 6618.0
H2AX 6737.0
RPA1 7064.0
TEX15 10327.0



REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION

REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION
853
set REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION
setSize 100
pANOVA 2.33e-06
s.dist -0.273
p.adjustANOVA 8.31e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708
H3C6 -10650
ERCC3 -10242
H4C3 -9942
POLR1E -9865
SAP30BP -9662
H2BC12 -9581
H4C11 -9492
H4C9 -9486
H2BC5 -9371
DNMT3B -9346
H3-3A -9260
H4C16 -9179
H2AC4 -9092
TAF1B -8949
H2BC1 -8504
H4C13 -8401
H3-3B -8363
H3C8 -8260
H2BC3 -8237

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
H3C6 -10650.0
ERCC3 -10242.0
H4C3 -9942.0
POLR1E -9865.0
SAP30BP -9662.0
H2BC12 -9581.0
H4C11 -9492.0
H4C9 -9486.0
H2BC5 -9371.0
DNMT3B -9346.0
H3-3A -9260.0
H4C16 -9179.0
H2AC4 -9092.0
TAF1B -8949.0
H2BC1 -8504.0
H4C13 -8401.0
H3-3B -8363.0
H3C8 -8260.0
H2BC3 -8237.0
H2BC8 -8108.0
POLR2K -7697.0
H3C11 -7686.0
SAP18 -7662.0
TTF1 -7591.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
H2AJ -7338.0
SAP30 -7138.0
H2BC10 -6977.0
H3C3 -6933.0
H3C12 -6825.0
H2AC8 -6733.0
H2AC18 -6516.5
H2AC19 -6516.5
H2BC14 -6126.0
CCNH -6119.0
SUDS3 -5886.0
HDAC2 -5534.0
H3C2 -5478.0
TAF1D -5430.0
MBD2 -5352.0
H2AC7 -5340.5
H2BC7 -5340.5
POLR1D -4579.0
GTF2H5 -4378.0
TBP -4230.0
H4C4 -4007.0
H2BC21 -3732.0
GTF2H1 -3642.0
H4C6 -3568.0
H2AC14 -3377.0
SAP130 -3322.0
MNAT1 -3244.0
BAZ2A -3226.0
H3C4 -3045.0
POLR1G -2833.0
GTF2H3 -2584.0
POLR1B -2231.0
POLR1F -2165.0
SMARCA5 -1620.0
SIN3A -1392.0
H3C10 -1128.0
H4C12 -1092.0
H4C2 -859.0
POLR1C -455.0
POLR1H -194.0
H2BC13 1.0
ARID4B 1294.0
H4C8 1444.0
SAP30L 1574.0
H2BC26 1619.0
POLR1A 1793.0
CDK7 1850.0
POLR2L 1891.0
H2BC15 2203.0
ERCC2 2323.0
H2BC4 2363.0
H4C1 2583.0
SIRT1 2715.0
RRP8 2770.0
POLR2H 3091.0
H2AC20 3179.0
POLR2F 3701.0
SIN3B 3728.0
TAF1C 3808.0
H2BC17 4130.0
POLR2E 4421.0
H2BC11 4657.0
H3C1 4735.0
HDAC1 4949.0
TAF1A 4963.0
H4C5 5401.0
H2AZ2 5485.0
GTF2H4 5821.0
H2AC6 6426.0
H2AX 6737.0
DNMT1 6745.0
UBTF 6820.0



REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION

REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION
851
set REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION
setSize 98
pANOVA 2.38e-06
s.dist -0.276
p.adjustANOVA 8.33e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708
H3C6 -10650
H4C3 -9942
POLR1E -9865
EP300 -9776
H2BC12 -9581
H4C11 -9492
H4C9 -9486
H2BC5 -9371
H3-3A -9260
H4C16 -9179
H2AC4 -9092
TAF1B -8949
DDX21 -8858
GATAD2B -8745
H2BC1 -8504
KAT2B -8472
H4C13 -8401
H3-3B -8363
H3C8 -8260

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
H3C6 -10650.0
H4C3 -9942.0
POLR1E -9865.0
EP300 -9776.0
H2BC12 -9581.0
H4C11 -9492.0
H4C9 -9486.0
H2BC5 -9371.0
H3-3A -9260.0
H4C16 -9179.0
H2AC4 -9092.0
TAF1B -8949.0
DDX21 -8858.0
GATAD2B -8745.0
H2BC1 -8504.0
KAT2B -8472.0
H4C13 -8401.0
H3-3B -8363.0
H3C8 -8260.0
H2BC3 -8237.0
H2BC8 -8108.0
POLR2K -7697.0
H3C11 -7686.0
TTF1 -7591.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
H2AJ -7338.0
H2BC10 -6977.0
H3C3 -6933.0
H3C12 -6825.0
H2AC8 -6733.0
H2AC18 -6516.5
H2AC19 -6516.5
SF3B1 -6304.0
H2BC14 -6126.0
MBD3 -5903.0
GSK3B -5572.0
HDAC2 -5534.0
H3C2 -5478.0
TAF1D -5430.0
H2AC7 -5340.5
H2BC7 -5340.5
POLR1D -4579.0
TBP -4230.0
H4C4 -4007.0
BAZ1B -3837.0
H2BC21 -3732.0
H4C6 -3568.0
H2AC14 -3377.0
EHMT2 -3061.0
H3C4 -3045.0
MTA2 -2984.0
POLR1G -2833.0
GATAD2A -2405.0
POLR1B -2231.0
POLR1F -2165.0
SMARCA5 -1620.0
MTA1 -1189.0
H3C10 -1128.0
H4C12 -1092.0
DEK -1023.0
H4C2 -859.0
ACTB -471.0
POLR1C -455.0
MYBBP1A -440.0
POLR1H -194.0
RBBP4 -33.0
H2BC13 1.0
CBX3 174.0
CHD3 338.0
H4C8 1444.0
H2BC26 1619.0
POLR1A 1793.0
POLR2L 1891.0
MYO1C 2134.0
H2BC15 2203.0
H2BC4 2363.0
H4C1 2583.0
POLR2H 3091.0
H2AC20 3179.0
POLR2F 3701.0
TAF1C 3808.0
KAT2A 3907.0
H2BC17 4130.0
POLR2E 4421.0
H2BC11 4657.0
H3C1 4735.0
HDAC1 4949.0
TAF1A 4963.0
ERCC6 5141.0
H4C5 5401.0
H2AZ2 5485.0
CHD4 6248.0
H2AC6 6426.0
H2AX 6737.0
MTA3 6867.0



REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA

REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA
440
set REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA
setSize 65
pANOVA 2.98e-06
s.dist -0.335
p.adjustANOVA 0.000102



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708
H3C6 -10650
H4C3 -9942
H2BC12 -9581
H4C11 -9492
H4C9 -9486
JARID2 -9419
H2BC5 -9371
DNMT3B -9346
H3-3A -9260
H4C16 -9179
H2AC4 -9092
H2BC1 -8504
H4C13 -8401
H3-3B -8363
H3C8 -8260
H2BC3 -8237
H2BC8 -8108
H3C11 -7686
EZH2 -7675

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
H3C6 -10650.0
H4C3 -9942.0
H2BC12 -9581.0
H4C11 -9492.0
H4C9 -9486.0
JARID2 -9419.0
H2BC5 -9371.0
DNMT3B -9346.0
H3-3A -9260.0
H4C16 -9179.0
H2AC4 -9092.0
H2BC1 -8504.0
H4C13 -8401.0
H3-3B -8363.0
H3C8 -8260.0
H2BC3 -8237.0
H2BC8 -8108.0
H3C11 -7686.0
EZH2 -7675.0
H2AZ1 -7538.0
H2BC9 -7522.5
H3C7 -7522.5
H2AJ -7338.0
EED -7009.0
H2BC10 -6977.0
H3C3 -6933.0
H3C12 -6825.0
H2AC8 -6733.0
H2AC18 -6516.5
H2AC19 -6516.5
H2BC14 -6126.0
H3C2 -5478.0
H2AC7 -5340.5
H2BC7 -5340.5
H4C4 -4007.0
PHF19 -4003.0
H2BC21 -3732.0
H4C6 -3568.0
H2AC14 -3377.0
H3C4 -3045.0
H3C10 -1128.0
H4C12 -1092.0
PHF1 -1074.0
H4C2 -859.0
MTF2 -564.0
RBBP4 -33.0
H2BC13 1.0
H4C8 1444.0
DNMT3A 1573.0
H2BC26 1619.0
H2BC15 2203.0
H2BC4 2363.0
H4C1 2583.0
AEBP2 3010.0
H2AC20 3179.0
H2BC17 4130.0
H2BC11 4657.0
H3C1 4735.0
H4C5 5401.0
H2AZ2 5485.0
SUZ12 5843.0
H2AC6 6426.0
H2AX 6737.0
DNMT1 6745.0



REACTOME_HDACS_DEACETYLATE_HISTONES

REACTOME_HDACS_DEACETYLATE_HISTONES
548
set REACTOME_HDACS_DEACETYLATE_HISTONES
setSize 85
pANOVA 3.65e-06
s.dist -0.29
p.adjustANOVA 0.000122



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 -10708
H3C6 -10650
H4C3 -9942
H2BC12 -9581
H4C11 -9492
H4C9 -9486
H2BC5 -9371
H2AC16 -9348
RCOR1 -9289
H4C16 -9179
H2AC4 -9092
GATAD2B -8745
H2BC1 -8504
NCOR2 -8471
H4C13 -8401
H3C8 -8260
H2BC3 -8237
H2BC8 -8108
H3C11 -7686
SAP18 -7662

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 -10708.0
H3C6 -10650.0
H4C3 -9942.0
H2BC12 -9581.0
H4C11 -9492.0
H4C9 -9486.0
H2BC5 -9371.0
H2AC16 -9348.0
RCOR1 -9289.0
H4C16 -9179.0
H2AC4 -9092.0
GATAD2B -8745.0
H2BC1 -8504.0
NCOR2 -8471.0
H4C13 -8401.0
H3C8 -8260.0
H2BC3 -8237.0
H2BC8 -8108.0
H3C11 -7686.0
SAP18 -7662.0
H2BC9 -7522.5
H3C7 -7522.5
H2AC21 -7374.0
SAP30 -7138.0
H2BC10 -6977.0
H3C3 -6933.0
H3C12 -6825.0
H2AC8 -6733.0
H2AC18 -6516.5
H2AC19 -6516.5
H2AC1 -6275.0
HDAC10 -6199.0
H2BC14 -6126.0
MBD3 -5903.0
SUDS3 -5886.0
HDAC2 -5534.0
H3C2 -5478.0
H2AC7 -5340.5
H2BC7 -5340.5
ARID4A -5327.0
H2AC12 -5204.0
PHF21A -4143.0
TBL1XR1 -4015.0
H4C4 -4007.0
H2BC21 -3732.0
H4C6 -3568.0
H2AC14 -3377.0
H3C4 -3045.0
MTA2 -2984.0
GPS2 -2644.0
GATAD2A -2405.0
BRMS1 -2063.0
MTA1 -1189.0
H3C10 -1128.0
H4C12 -1092.0
KDM1A -970.0
H4C2 -859.0
REST -668.0
H2AC17 -112.0
RBBP4 -33.0
H2BC13 1.0
HMG20B 51.0
H2AC25 146.0
CHD3 338.0
ARID4B 1294.0
H4C8 1444.0
SAP30L 1574.0
H2BC26 1619.0
NCOR1 1776.0
H2AC15 1986.0
H2BC15 2203.0
H2BC4 2363.0
HDAC3 2573.0
H4C1 2583.0
H2AC20 3179.0
H2BC17 4130.0
H2BC11 4657.0
H3C1 4735.0
HDAC1 4949.0
H4C5 5401.0
CHD4 6248.0
H2AC6 6426.0
MTA3 6867.0
H2AC13 8584.0
H2AC11 9249.0



REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION

REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION
786
set REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION
setSize 299
pANOVA 3.73e-06
s.dist -0.155
p.adjustANOVA 0.000123



Top enriched genes

Top 20 genes
GeneID Gene Rank
AREG -10981
MOGS -10704
CALR -10512
CTSZ -10474
TRAPPC3 -10403
TRIM13 -10397
ANKRD28 -10373
TUBA3D -10346
TRAPPC10 -10290
DCTN2 -10239
CD59 -10212
TUBB4B -10078
TMED2 -9959
PDIA3 -9862
B4GALT5 -9844
ST3GAL2 -9716
RPN1 -9708
CMAS -9646
B4GALT6 -9639
UBC -9558

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AREG -10981.0
MOGS -10704.0
CALR -10512.0
CTSZ -10474.0
TRAPPC3 -10403.0
TRIM13 -10397.0
ANKRD28 -10373.0
TUBA3D -10346.0
TRAPPC10 -10290.0
DCTN2 -10239.0
CD59 -10212.0
TUBB4B -10078.0
TMED2 -9959.0
PDIA3 -9862.0
B4GALT5 -9844.0
ST3GAL2 -9716.0
RPN1 -9708.0
CMAS -9646.0
B4GALT6 -9639.0
UBC -9558.0
RNF103 -9544.0
DYNLL1 -9489.0
DYNC1LI1 -9445.0
CTSA -9402.0
STX5 -9365.0
ALG10 -9343.0
RFT1 -9301.0
NAPA -9160.0
ARF3 -9134.0
ST8SIA3 -9111.0
TMED10 -9047.0
CANX -9039.0
TRAPPC6B -9014.0
ARF1 -8984.0
GOSR1 -8917.0
B4GALT1 -8905.0
MIA2 -8834.0
SEC24A -8812.0
TUBB4A -8809.0
GOLGB1 -8626.0
EDEM2 -8585.0
TGFA -8513.0
DHDDS -8455.0
STT3A -8094.0
TMED3 -8012.0
ALG8 -7976.0
ST3GAL6 -7925.0
CGA -7924.0
TMED7 -7896.0
UBXN1 -7778.0
GFPT1 -7687.0
COPB2 -7633.0
COG3 -7385.0
KDELR1 -7280.0
AMDHD2 -7272.0
SAR1B -7270.0
GORASP1 -7243.0
SLC35C1 -7101.0
MGAT4A -7026.0
MGAT4B -7011.0
UAP1 -6970.0
SEC24D -6903.0
TUBAL3 -6859.0
COG1 -6840.0
TUBA4A -6826.0
NAPG -6808.0
EDEM1 -6706.0
COPG1 -6605.0
DYNC1I2 -6523.0
SEL1L -6501.0
TUBB3 -6481.0
SLC17A5 -6465.0
TUBA4B -6407.0
ALG6 -6352.0
FUCA1 -6344.0
LHB -6341.0
NUDT14 -6331.0
STX17 -6260.0
MAN2A1 -6229.0
ST3GAL4 -6174.0
SEC13 -6136.0
ACTR1A -6083.0
TUBA1A -6069.0
SEC23A -5922.0
GNE -5595.0
SEC22A -5585.0
RNF5 -5578.0
RAB1A -5565.0
SEC31A -5444.0
COPA -5440.0
GBF1 -5436.0
TUBB2A -5397.0
TFG -5371.0
DCTN6 -5234.0
SRD5A3 -5180.0
NAGK -5092.0
RAB1B -5084.0
CNIH1 -5002.0
ANK3 -4879.0
NPL -4806.0
MVD -4730.0
VCP -4679.0
ARFGAP3 -4646.0
MAN1A1 -4644.0
GMPPA -4599.0
ST8SIA4 -4565.0
TUBB6 -4561.0
DPM3 -4545.0
FOLR1 -4374.0
B4GALT3 -4359.0
ALG10B -4329.0
DYNC1H1 -4301.0
NUS1 -4295.0
ST3GAL1 -4277.0
KDELR3 -4232.0
RPN2 -4174.0
ST8SIA6 -4158.0
GMDS -4125.0
F5 -4071.0
PMM1 -3942.0
KDELR2 -3830.0
GOLGA2 -3802.0
TRAPPC6A -3667.0
NEU3 -3625.0
NAPB -3603.0
SEC24C -3587.0
LMAN1 -3525.0
LMAN2L -3494.0
MLEC -3475.0
B4GALT2 -3460.0
COPB1 -3302.0
DCTN4 -3208.0
TUBA1C -3186.0
SPTBN1 -3118.0
RAD23B -3034.0
TRAPPC5 -2822.0
CHST10 -2817.0
COG4 -2801.0
PMM2 -2728.0
CAPZA2 -2683.0
USO1 -2632.0
TUBA8 -2524.0
ST6GALNAC4 -2442.0
MGAT1 -2370.0
NGLY1 -2361.0
ALG3 -2335.0
MPI -2232.0
SPTAN1 -2199.0
DYNC1I1 -2149.0
COG7 -2146.0
TUBB2B -2109.0
FPGT -2051.0
SEC23IP -2026.0
DCTN1 -2023.0
DERL1 -1955.0
PREB -1919.0
MAN2A2 -1835.0
RNF185 -1825.0
ALG2 -1819.0
OS9 -1652.0
B4GALT4 -1586.0
CSNK1D -1577.0
CAPZB -1568.0
DPM1 -1536.0
ALG9 -1528.0
MAN1B1 -1523.0
CAPZA1 -1452.0
PPP6C -1377.0
ANK2 -1346.0
SEC22C -1249.0
GOSR2 -1204.0
MARCHF6 -1141.0
MANEA -838.0
COPE -594.0
COG8 -544.0
SEC22B -384.0
TUBA3C -374.0
DERL2 -335.0
LMAN2 -232.0
MPDU1 -154.0
TRAPPC4 -98.0
TUBA3E -95.0
SEC24B -71.0
ARF4 -67.0
SYVN1 -66.0
SCFD1 -28.0
MAN1C1 -20.0
MCFD2 29.0
DPAGT1 100.0
MGAT5 132.0
TBC1D20 206.0
UGGT1 212.0
CHST8 334.0
PPP6R3 477.0
B4GALNT2 610.0
ARFGAP2 654.0
DOLK 742.0
ST3GAL3 852.0
YKT6 867.0
ALG5 879.0
MIA3 1018.0
COPZ1 1020.0
COPG2 1041.0
ASGR2 1042.0
COG2 1148.0
NEU1 1282.0
UBB 1320.0
TUSC3 1324.0
FUOM 1332.0
ST6GAL2 1360.0
TRAPPC1 1479.0
ST6GALNAC6 1488.0
DAD1 1610.0
FUT8 1624.0
COG6 1816.0
ARCN1 1940.0
ST6GAL1 2058.0
FUT3 2072.0
CTSC 2104.0
SEC16A 2108.0
MGAT4C 2174.0
RPS27A 2313.0
BET1L 2379.0
BET1 2489.0
EDEM3 2525.0
DYNC1LI2 2640.0
UBA52 2643.0
SPTBN4 2646.0
TMED9 2667.0
UGGT2 2670.0
SPTA1 2809.0
PGM3 2883.0
COG5 2921.0
GFUS 3013.0
ALG14 3063.0
GANAB 3147.0
PRKCSH 3152.0
ARF5 3512.0
MAN1A2 3574.0
AMFR 3860.0
ALG11 3900.0
SLC35A1 4066.0
TRAPPC9 4079.0
PPP6R1 4206.0
ST8SIA1 4240.0
NSF 4491.0
DPM2 4633.0
TUBA1B 4671.0
PSMC1 4758.0
CD55 4766.0
UMOD 4826.0
ANK1 4865.0
NANS 5072.0
TMEM115 5094.0
NANP 5187.0
ST6GALNAC3 5208.0
FCSK 5343.0
CNIH2 5432.0
GFPT2 5466.0
TUBB1 5561.0
ST6GALNAC5 5573.0
ST6GALNAC2 5581.0
GLB1 5752.0
DCTN5 5779.0
MGAT2 5907.5
NEU2 6067.0
TRAPPC2L 6188.0
GMPPB 6333.0
ALG12 6394.0
ACTR10 6469.0
LMAN1L 6508.0
ST8SIA5 6705.0
SERPINA1 6864.0
ASGR1 7332.0
GNPNAT1 7429.0
NEU4 7462.0
ST3GAL5 7524.0
CAPZA3 7525.0
ENGASE 7543.0
CNIH3 7590.0
SPTBN2 7669.0
DDOST 7801.0
DCTN3 7804.0
COPZ2 7836.0
DOLPP1 7877.0
RNF139 8220.0
GRIA1 8366.0
ARFGAP1 8891.0
SEC16B 8958.0
DYNLL2 9125.0
COL7A1 9254.0
INS 9345.0
MGAT3 9420.0
SPTBN5 9424.0
ALG1 9483.0
SPTB 9535.0
ST8SIA2 9721.0
ST6GALNAC1 10437.0
TUBB8 10871.0



Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report