date generated: 2022-06-06

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

##                     x
##         -468.74375579
## A1BG      -0.19116969
## A1CF       1.55834102
## A2M       -0.29772738
## A3GALT2    1.30005608
## A4GALT     0.01967718
Here are some metrics about the input data profile:
Profile metrics
Profile metrics
num_genesets 2408
num_genes_in_profile 16477
duplicated_genes_present 0
num_profile_genes_in_sets 8847
num_profile_genes_not_in_sets 7630

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt
Gene sets metrics
Gene sets metrics
num_genesets 2408
num_genesets_excluded 1004
num_genesets_included 1404

Differential pathway expression


Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets
set setSize pANOVA s.dist p.adjustANOVA
Major pathway of rRNA processing in the nucleolus and cytosol 148 7.55e-15 -0.3700 1.06e-11
SRP-dependent cotranslational protein targeting to membrane 83 2.52e-14 -0.4840 1.24e-11
rRNA processing in the nucleus and cytosol 155 2.66e-14 -0.3540 1.24e-11
Response of EIF2AK4 (GCN2) to amino acid deficiency 72 1.15e-12 -0.4850 3.56e-10
Peptide chain elongation 60 1.66e-12 -0.5270 3.56e-10
Eukaryotic Translation Termination 63 1.73e-12 -0.5140 3.56e-10
Viral mRNA Translation 60 1.88e-12 -0.5260 3.56e-10
Selenocysteine synthesis 63 2.03e-12 -0.5120 3.56e-10
Metabolism 1845 2.70e-12 0.0997 3.92e-10
Eukaryotic Translation Elongation 63 2.79e-12 -0.5090 3.92e-10
Cap-dependent Translation Initiation 87 9.53e-12 -0.4230 1.12e-09
Eukaryotic Translation Initiation 87 9.53e-12 -0.4230 1.12e-09
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 65 1.98e-11 -0.4810 2.01e-09
GTP hydrolysis and joining of the 60S ribosomal subunit 81 2.00e-11 -0.4310 2.01e-09
Formation of a pool of free 40S subunits 71 2.96e-11 -0.4560 2.77e-09
L13a-mediated translational silencing of Ceruloplasmin expression 79 3.62e-11 -0.4310 3.18e-09
The citric acid (TCA) cycle and respiratory electron transport 150 6.21e-11 0.3090 5.13e-09
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 83 1.19e-10 -0.4090 8.76e-09
Nonsense-Mediated Decay (NMD) 83 1.19e-10 -0.4090 8.76e-09
rRNA processing 176 1.45e-09 -0.2650 1.01e-07
Metabolism of lipids 669 2.49e-09 0.1360 1.67e-07
Regulation of expression of SLITs and ROBOs 133 2.86e-09 -0.2980 1.82e-07
Metabolism of RNA 604 2.49e-08 -0.1330 1.52e-06
Influenza Viral RNA Transcription and Replication 103 4.97e-08 -0.3110 2.91e-06
Formation of the ternary complex, and subsequently, the 43S complex 42 4.75e-07 -0.4490 2.67e-05
Influenza Infection 120 6.95e-07 -0.2620 3.75e-05
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 102 7.85e-07 0.2830 4.08e-05
Mitochondrial Fatty Acid Beta-Oxidation 34 9.41e-07 0.4860 4.72e-05
Selenoamino acid metabolism 84 1.09e-06 -0.3080 5.17e-05
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 106 1.11e-06 -0.2740 5.17e-05
Fatty acid metabolism 160 1.41e-06 0.2210 6.40e-05
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 48 2.23e-06 -0.3950 9.77e-05
Citric acid cycle (TCA cycle) 22 2.43e-06 0.5800 1.03e-04
Respiratory electron transport 83 2.51e-06 0.2990 1.04e-04
Signaling by ROBO receptors 178 2.76e-06 -0.2040 1.10e-04
Ribosomal scanning and start codon recognition 48 2.82e-06 -0.3910 1.10e-04
Pyruvate metabolism and Citric Acid (TCA) cycle 52 4.40e-06 0.3680 1.67e-04
Translation initiation complex formation 47 4.56e-06 -0.3870 1.68e-04
Bile acid and bile salt metabolism 37 1.16e-05 0.4170 4.19e-04
Adaptive Immune System 643 2.24e-05 -0.0985 7.85e-04
Transport of small molecules 656 3.34e-05 0.0954 1.14e-03
Peroxisomal lipid metabolism 27 3.54e-05 0.4600 1.18e-03
Synthesis of bile acids and bile salts 29 6.39e-05 0.4290 2.09e-03
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol 19 8.00e-05 0.5230 2.55e-03
Separation of Sister Chromatids 157 1.67e-04 -0.1740 5.20e-03
Generation of second messenger molecules 24 2.00e-04 -0.4380 6.12e-03
TCR signaling 96 2.89e-04 -0.2140 8.63e-03
Complex I biogenesis 46 3.44e-04 0.3050 1.01e-02
PD-1 signaling 15 5.93e-04 -0.5120 1.70e-02
Protein localization 144 6.18e-04 0.1650 1.73e-02


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pANOVA s.dist p.adjustANOVA
Major pathway of rRNA processing in the nucleolus and cytosol 148 7.55e-15 -3.70e-01 1.06e-11
SRP-dependent cotranslational protein targeting to membrane 83 2.52e-14 -4.84e-01 1.24e-11
rRNA processing in the nucleus and cytosol 155 2.66e-14 -3.54e-01 1.24e-11
Response of EIF2AK4 (GCN2) to amino acid deficiency 72 1.15e-12 -4.85e-01 3.56e-10
Peptide chain elongation 60 1.66e-12 -5.27e-01 3.56e-10
Eukaryotic Translation Termination 63 1.73e-12 -5.14e-01 3.56e-10
Viral mRNA Translation 60 1.88e-12 -5.26e-01 3.56e-10
Selenocysteine synthesis 63 2.03e-12 -5.12e-01 3.56e-10
Metabolism 1845 2.70e-12 9.97e-02 3.92e-10
Eukaryotic Translation Elongation 63 2.79e-12 -5.09e-01 3.92e-10
Cap-dependent Translation Initiation 87 9.53e-12 -4.23e-01 1.12e-09
Eukaryotic Translation Initiation 87 9.53e-12 -4.23e-01 1.12e-09
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 65 1.98e-11 -4.81e-01 2.01e-09
GTP hydrolysis and joining of the 60S ribosomal subunit 81 2.00e-11 -4.31e-01 2.01e-09
Formation of a pool of free 40S subunits 71 2.96e-11 -4.56e-01 2.77e-09
L13a-mediated translational silencing of Ceruloplasmin expression 79 3.62e-11 -4.31e-01 3.18e-09
The citric acid (TCA) cycle and respiratory electron transport 150 6.21e-11 3.09e-01 5.13e-09
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 83 1.19e-10 -4.09e-01 8.76e-09
Nonsense-Mediated Decay (NMD) 83 1.19e-10 -4.09e-01 8.76e-09
rRNA processing 176 1.45e-09 -2.65e-01 1.01e-07
Metabolism of lipids 669 2.49e-09 1.36e-01 1.67e-07
Regulation of expression of SLITs and ROBOs 133 2.86e-09 -2.98e-01 1.82e-07
Metabolism of RNA 604 2.49e-08 -1.33e-01 1.52e-06
Influenza Viral RNA Transcription and Replication 103 4.97e-08 -3.11e-01 2.91e-06
Formation of the ternary complex, and subsequently, the 43S complex 42 4.75e-07 -4.49e-01 2.67e-05
Influenza Infection 120 6.95e-07 -2.62e-01 3.75e-05
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 102 7.85e-07 2.83e-01 4.08e-05
Mitochondrial Fatty Acid Beta-Oxidation 34 9.41e-07 4.86e-01 4.72e-05
Selenoamino acid metabolism 84 1.09e-06 -3.08e-01 5.17e-05
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 106 1.11e-06 -2.74e-01 5.17e-05
Fatty acid metabolism 160 1.41e-06 2.21e-01 6.40e-05
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 48 2.23e-06 -3.95e-01 9.77e-05
Citric acid cycle (TCA cycle) 22 2.43e-06 5.80e-01 1.03e-04
Respiratory electron transport 83 2.51e-06 2.99e-01 1.04e-04
Signaling by ROBO receptors 178 2.76e-06 -2.04e-01 1.10e-04
Ribosomal scanning and start codon recognition 48 2.82e-06 -3.91e-01 1.10e-04
Pyruvate metabolism and Citric Acid (TCA) cycle 52 4.40e-06 3.68e-01 1.67e-04
Translation initiation complex formation 47 4.56e-06 -3.87e-01 1.68e-04
Bile acid and bile salt metabolism 37 1.16e-05 4.17e-01 4.19e-04
Adaptive Immune System 643 2.24e-05 -9.85e-02 7.85e-04
Transport of small molecules 656 3.34e-05 9.54e-02 1.14e-03
Peroxisomal lipid metabolism 27 3.54e-05 4.60e-01 1.18e-03
Synthesis of bile acids and bile salts 29 6.39e-05 4.29e-01 2.09e-03
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol 19 8.00e-05 5.23e-01 2.55e-03
Separation of Sister Chromatids 157 1.67e-04 -1.74e-01 5.20e-03
Generation of second messenger molecules 24 2.00e-04 -4.38e-01 6.12e-03
TCR signaling 96 2.89e-04 -2.14e-01 8.63e-03
Complex I biogenesis 46 3.44e-04 3.05e-01 1.01e-02
PD-1 signaling 15 5.93e-04 -5.12e-01 1.70e-02
Protein localization 144 6.18e-04 1.65e-01 1.73e-02
TNFR2 non-canonical NF-kB pathway 86 6.31e-04 -2.13e-01 1.74e-02
Fc epsilon receptor (FCERI) signaling 129 7.14e-04 -1.73e-01 1.93e-02
Intrinsic Pathway of Fibrin Clot Formation 22 7.80e-04 4.14e-01 2.07e-02
Cellular responses to stress 442 8.29e-04 -9.30e-02 2.16e-02
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 67 9.08e-04 -2.34e-01 2.32e-02
Cellular responses to external stimuli 449 1.01e-03 -9.08e-02 2.52e-02
APC/C:Cdc20 mediated degradation of mitotic proteins 66 1.03e-03 -2.34e-01 2.52e-02
Recycling of bile acids and salts 15 1.05e-03 4.89e-01 2.52e-02
rRNA modification in the nucleus and cytosol 54 1.06e-03 -2.58e-01 2.52e-02
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism 12 1.14e-03 5.42e-01 2.63e-02
alpha-linolenic acid (ALA) metabolism 12 1.14e-03 5.42e-01 2.63e-02
SLC-mediated transmembrane transport 233 1.19e-03 1.23e-01 2.69e-02
tRNA processing in the mitochondrion 18 1.34e-03 4.37e-01 2.99e-02
TNFs bind their physiological receptors 25 1.43e-03 -3.69e-01 3.13e-02
Metabolism of porphyrins 23 1.52e-03 3.82e-01 3.29e-02
rRNA processing in the mitochondrion 21 1.58e-03 3.98e-01 3.36e-02
Downstream TCR signaling 76 1.63e-03 -2.09e-01 3.37e-02
Collagen chain trimerization 35 1.63e-03 -3.08e-01 3.37e-02
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 64 1.76e-03 -2.26e-01 3.49e-02
Regulation of APC/C activators between G1/S and early anaphase 71 1.76e-03 -2.15e-01 3.49e-02
Transcriptional activation of mitochondrial biogenesis 51 1.76e-03 2.53e-01 3.49e-02
Cdc20:Phospho-APC/C mediated degradation of Cyclin A 63 1.84e-03 -2.27e-01 3.58e-02
C-type lectin receptors (CLRs) 114 1.89e-03 -1.69e-01 3.63e-02
Sphingolipid metabolism 79 2.05e-03 2.01e-01 3.89e-02
Downstream signaling events of B Cell Receptor (BCR) 69 2.14e-03 -2.14e-01 4.01e-02
Mitochondrial biogenesis 82 2.53e-03 1.93e-01 4.60e-02
Regulation of insulin secretion 72 2.55e-03 2.06e-01 4.60e-02
Prolactin receptor signaling 15 2.56e-03 -4.50e-01 4.60e-02
Unblocking of NMDA receptors, glutamate binding and activation 20 2.66e-03 -3.88e-01 4.73e-02
L1CAM interactions 96 2.89e-03 1.76e-01 5.04e-02
APC/C-mediated degradation of cell cycle proteins 78 2.94e-03 -1.95e-01 5.04e-02
Regulation of mitotic cell cycle 78 2.94e-03 -1.95e-01 5.04e-02
Assembly of collagen fibrils and other multimeric structures 49 2.98e-03 -2.45e-01 5.04e-02
Mitochondrial calcium ion transport 20 3.12e-03 3.82e-01 5.22e-02
RNA Polymerase II Transcription 1008 3.27e-03 -5.52e-02 5.41e-02
Sema4D in semaphorin signaling 23 3.60e-03 3.51e-01 5.82e-02
Long-term potentiation 22 3.61e-03 -3.58e-01 5.82e-02
Heme degradation 12 3.87e-03 4.82e-01 6.11e-02
Phospholipid metabolism 196 3.89e-03 1.20e-01 6.11e-02
Transport of inorganic cations/anions and amino acids/oligopeptides 103 3.92e-03 1.65e-01 6.11e-02
Translocation of ZAP-70 to Immunological synapse 10 4.33e-03 -5.21e-01 6.68e-02
APC/C:Cdc20 mediated degradation of Securin 58 4.42e-03 -2.16e-01 6.75e-02
Glyoxylate metabolism and glycine degradation 29 4.62e-03 3.04e-01 6.97e-02
tRNA Aminoacylation 38 4.81e-03 2.64e-01 7.18e-02
Collagen formation 78 5.16e-03 -1.83e-01 7.60e-02
Stabilization of p53 46 5.20e-03 -2.38e-01 7.60e-02
Cell Cycle Checkpoints 235 5.62e-03 -1.05e-01 8.13e-02
LDL clearance 18 5.75e-03 3.76e-01 8.24e-02
Gene expression (Transcription) 1138 5.84e-03 -4.89e-02 8.28e-02
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 37 5.95e-03 2.61e-01 8.29e-02
Apoptotic cleavage of cell adhesion proteins 11 6.07e-03 4.78e-01 8.29e-02
Mitotic Spindle Checkpoint 104 6.11e-03 -1.56e-01 8.29e-02
Branched-chain amino acid catabolism 20 6.11e-03 3.54e-01 8.29e-02
Mitochondrial protein import 54 6.14e-03 2.16e-01 8.29e-02
Processing of SMDT1 13 6.61e-03 4.35e-01 8.84e-02
Resolution of Sister Chromatid Cohesion 101 6.70e-03 -1.56e-01 8.87e-02
Immune System 1805 6.78e-03 -3.90e-02 8.87e-02
Collagen biosynthesis and modifying enzymes 57 6.83e-03 -2.07e-01 8.87e-02
Mitotic Metaphase and Anaphase 208 7.12e-03 -1.08e-01 9.17e-02
Dectin-2 family 15 7.42e-03 -3.99e-01 9.47e-02
Mitochondrial tRNA aminoacylation 18 7.57e-03 3.64e-01 9.57e-02
Cross-presentation of soluble exogenous antigens (endosomes) 43 7.80e-03 -2.35e-01 9.78e-02
Metabolism of vitamins and cofactors 168 8.17e-03 1.18e-01 9.91e-02
Antigen processing-Cross presentation 86 8.18e-03 -1.65e-01 9.91e-02
Phosphorylation of CD3 and TCR zeta chains 14 8.19e-03 -4.08e-01 9.91e-02
FCGR activation 25 8.19e-03 -3.06e-01 9.91e-02
Hemostasis 536 8.47e-03 6.67e-02 1.01e-01
The role of GTSE1 in G2/M progression after G2 checkpoint 49 8.48e-03 -2.17e-01 1.01e-01
RUNX1 regulates transcription of genes involved in differentiation of HSCs 66 8.72e-03 -1.87e-01 1.03e-01
Mitotic Anaphase 207 8.78e-03 -1.06e-01 1.03e-01
Mitochondrial translation 88 8.85e-03 1.62e-01 1.03e-01
Transport of vitamins, nucleosides, and related molecules 39 8.96e-03 2.42e-01 1.03e-01
Miscellaneous transport and binding events 21 9.02e-03 3.29e-01 1.03e-01
Adrenaline,noradrenaline inhibits insulin secretion 24 9.08e-03 3.08e-01 1.03e-01
Nucleobase catabolism 32 9.29e-03 2.66e-01 1.04e-01
Generic Transcription Pathway 894 9.33e-03 -5.16e-02 1.04e-01
Sphingolipid de novo biosynthesis 39 1.01e-02 2.38e-01 1.12e-01
Neuronal System 353 1.07e-02 7.93e-02 1.17e-01
Organelle biogenesis and maintenance 257 1.08e-02 9.25e-02 1.18e-01
Interaction between L1 and Ankyrins 28 1.16e-02 2.76e-01 1.25e-01
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) 13 1.17e-02 -4.04e-01 1.25e-01
Cristae formation 24 1.20e-02 2.96e-01 1.27e-01
Beta-oxidation of very long chain fatty acids 10 1.24e-02 4.57e-01 1.31e-01
cGMP effects 15 1.25e-02 3.72e-01 1.31e-01
M Phase 323 1.30e-02 -8.06e-02 1.35e-01
Vif-mediated degradation of APOBEC3G 44 1.34e-02 -2.15e-01 1.38e-01
Assembly and cell surface presentation of NMDA receptors 22 1.35e-02 -3.04e-01 1.38e-01
MAPK6/MAPK4 signaling 78 1.36e-02 -1.62e-01 1.39e-01
Deposition of new CENPA-containing nucleosomes at the centromere 29 1.40e-02 -2.64e-01 1.40e-01
Nucleosome assembly 29 1.40e-02 -2.64e-01 1.40e-01
Autodegradation of Cdh1 by Cdh1:APC/C 55 1.43e-02 -1.91e-01 1.42e-01
Regulation of RUNX3 expression and activity 47 1.46e-02 -2.06e-01 1.44e-01
ER to Golgi Anterograde Transport 124 1.47e-02 -1.27e-01 1.44e-01
GABA synthesis, release, reuptake and degradation 17 1.52e-02 3.40e-01 1.48e-01
Regulation of TP53 Expression and Degradation 32 1.54e-02 -2.47e-01 1.49e-01
FCERI mediated NF-kB activation 79 1.55e-02 -1.58e-01 1.49e-01
Assembly Of The HIV Virion 14 1.59e-02 -3.72e-01 1.52e-01
Recycling pathway of L1 27 1.64e-02 2.67e-01 1.56e-01
APC/C:Cdc20 mediated degradation of Cyclin B 20 1.67e-02 -3.09e-01 1.56e-01
Triglyceride metabolism 34 1.69e-02 2.37e-01 1.56e-01
Costimulation by the CD28 family 60 1.69e-02 -1.78e-01 1.56e-01
Pyrimidine catabolism 10 1.72e-02 4.35e-01 1.56e-01
Glutamate binding, activation of AMPA receptors and synaptic plasticity 27 1.72e-02 -2.65e-01 1.56e-01
Trafficking of AMPA receptors 27 1.72e-02 -2.65e-01 1.56e-01
Formation of Fibrin Clot (Clotting Cascade) 36 1.73e-02 2.29e-01 1.56e-01
Synthesis of bile acids and bile salts via 24-hydroxycholesterol 10 1.74e-02 4.34e-01 1.56e-01
Phase I - Functionalization of compounds 88 1.81e-02 1.46e-01 1.62e-01
Sema4D induced cell migration and growth-cone collapse 19 1.82e-02 3.13e-01 1.62e-01
Regulation of TP53 Degradation 31 1.87e-02 -2.44e-01 1.65e-01
Mitochondrial translation elongation 83 1.92e-02 1.49e-01 1.66e-01
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 64 1.92e-02 -1.69e-01 1.66e-01
Transcriptional regulation by RUNX2 107 1.92e-02 -1.31e-01 1.66e-01
Extracellular matrix organization 265 1.97e-02 -8.34e-02 1.68e-01
p53-Dependent G1 DNA Damage Response 55 1.98e-02 -1.82e-01 1.68e-01
p53-Dependent G1/S DNA damage checkpoint 55 1.98e-02 -1.82e-01 1.68e-01
SCF-beta-TrCP mediated degradation of Emi1 47 2.01e-02 -1.96e-01 1.68e-01
Biotin transport and metabolism 10 2.03e-02 4.24e-01 1.68e-01
Glycerophospholipid biosynthesis 120 2.03e-02 1.23e-01 1.68e-01
Removal of aminoterminal propeptides from gamma-carboxylated proteins 10 2.05e-02 4.23e-01 1.68e-01
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 89 2.05e-02 -1.42e-01 1.68e-01
Amplification of signal from the kinetochores 89 2.05e-02 -1.42e-01 1.68e-01
Potassium Channels 90 2.06e-02 1.41e-01 1.68e-01
Infectious disease 698 2.13e-02 -5.14e-02 1.73e-01
Signaling by the B Cell Receptor (BCR) 112 2.14e-02 -1.26e-01 1.73e-01
Phospholipase C-mediated cascade; FGFR3 12 2.16e-02 3.83e-01 1.73e-01
Aflatoxin activation and detoxification 17 2.17e-02 3.22e-01 1.73e-01
Metabolism of steroids 130 2.23e-02 1.16e-01 1.77e-01
ER-Phagosome pathway 74 2.30e-02 -1.53e-01 1.80e-01
Scavenging by Class A Receptors 17 2.31e-02 -3.18e-01 1.80e-01
Interleukin-10 signaling 37 2.31e-02 -2.16e-01 1.80e-01
Autodegradation of the E3 ubiquitin ligase COP1 42 2.32e-02 -2.02e-01 1.80e-01
EML4 and NUDC in mitotic spindle formation 93 2.40e-02 -1.36e-01 1.85e-01
Cytosolic sulfonation of small molecules 22 2.41e-02 2.78e-01 1.85e-01
Regulation of RAS by GAPs 58 2.46e-02 -1.71e-01 1.87e-01
Regulation of activated PAK-2p34 by proteasome mediated degradation 42 2.47e-02 -2.00e-01 1.87e-01
Defective B3GALTL causes Peters-plus syndrome (PpS) 36 2.48e-02 -2.16e-01 1.87e-01
Hedgehog ‘on’ state 74 2.50e-02 -1.51e-01 1.87e-01
Triglyceride biosynthesis 13 2.51e-02 3.59e-01 1.87e-01
Translation 248 2.53e-02 -8.26e-02 1.88e-01
Interconversion of nucleotide di- and triphosphates 27 2.57e-02 -2.48e-01 1.90e-01
Transcriptional regulation by RUNX3 82 2.60e-02 -1.42e-01 1.91e-01
Nitric oxide stimulates guanylate cyclase 19 2.63e-02 2.94e-01 1.92e-01
Mismatch Repair 13 2.70e-02 3.54e-01 1.95e-01
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 13 2.70e-02 3.54e-01 1.95e-01
Classical antibody-mediated complement activation 18 2.70e-02 -3.01e-01 1.95e-01
Activation of NF-kappaB in B cells 57 2.75e-02 -1.69e-01 1.97e-01
Peroxisomal protein import 58 2.79e-02 1.67e-01 1.99e-01
STING mediated induction of host immune responses 15 2.80e-02 -3.28e-01 1.99e-01
G alpha (12/13) signalling events 71 2.83e-02 1.51e-01 1.99e-01
Mitochondrial translation termination 83 2.84e-02 1.39e-01 1.99e-01
FGFR3 mutant receptor activation 11 2.86e-02 3.81e-01 1.99e-01
Signaling by activated point mutants of FGFR3 11 2.86e-02 3.81e-01 1.99e-01
Post-translational protein phosphorylation 100 2.91e-02 1.26e-01 2.01e-01
O-glycosylation of TSR domain-containing proteins 37 2.94e-02 -2.07e-01 2.02e-01
CDK-mediated phosphorylation and removal of Cdc6 63 2.96e-02 -1.59e-01 2.02e-01
Negative regulation of NOTCH4 signaling 47 2.96e-02 -1.83e-01 2.02e-01
Cytochrome P450 - arranged by substrate type 58 3.00e-02 1.65e-01 2.02e-01
Degradation of the extracellular matrix 99 3.00e-02 -1.26e-01 2.02e-01
SCF(Skp2)-mediated degradation of p27/p21 53 3.04e-02 -1.72e-01 2.04e-01
G1/S DNA Damage Checkpoints 56 3.09e-02 -1.67e-01 2.07e-01
Cell-extracellular matrix interactions 16 3.14e-02 3.11e-01 2.08e-01
Creation of C4 and C2 activators 24 3.15e-02 -2.54e-01 2.08e-01
Regulation of pyruvate dehydrogenase (PDH) complex 15 3.18e-02 3.20e-01 2.10e-01
IRF3-mediated induction of type I IFN 12 3.21e-02 -3.57e-01 2.11e-01
NIK–>noncanonical NF-kB signaling 51 3.25e-02 -1.73e-01 2.12e-01
Integration of energy metabolism 100 3.29e-02 1.24e-01 2.14e-01
Membrane binding and targetting of GAG proteins 12 3.33e-02 -3.55e-01 2.15e-01
Synthesis And Processing Of GAG, GAGPOL Polyproteins 12 3.33e-02 -3.55e-01 2.15e-01
APC-Cdc20 mediated degradation of Nek2A 22 3.36e-02 -2.62e-01 2.15e-01
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) 15 3.38e-02 3.17e-01 2.15e-01
Diseases of hemostasis 15 3.38e-02 3.17e-01 2.15e-01
DAP12 interactions 35 3.46e-02 -2.06e-01 2.19e-01
Apoptotic execution phase 50 3.51e-02 1.72e-01 2.21e-01
Class I MHC mediated antigen processing & presentation 331 3.53e-02 -6.75e-02 2.21e-01
Signal regulatory protein family interactions 12 3.60e-02 -3.50e-01 2.25e-01
Mitochondrial translation initiation 82 3.65e-02 1.34e-01 2.26e-01
Signaling by Interleukins 387 3.67e-02 -6.20e-02 2.26e-01
Metabolism of fat-soluble vitamins 41 3.70e-02 1.88e-01 2.26e-01
Bicarbonate transporters 10 3.70e-02 3.81e-01 2.26e-01
Regulation of ornithine decarboxylase (ODC) 45 3.72e-02 -1.80e-01 2.26e-01
PI-3K cascade:FGFR3 17 3.73e-02 2.92e-01 2.26e-01
CD28 dependent Vav1 pathway 12 3.80e-02 -3.46e-01 2.29e-01
Ovarian tumor domain proteases 33 3.82e-02 2.09e-01 2.29e-01
Initiation of Nuclear Envelope (NE) Reformation 16 3.83e-02 2.99e-01 2.29e-01
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 114 3.83e-02 1.12e-01 2.29e-01
Formation of TC-NER Pre-Incision Complex 49 3.90e-02 -1.71e-01 2.31e-01
RHO GTPases activate IQGAPs 11 3.90e-02 3.59e-01 2.31e-01
GLI3 is processed to GLI3R by the proteasome 50 3.99e-02 -1.68e-01 2.35e-01
CLEC7A (Dectin-1) signaling 88 4.04e-02 -1.26e-01 2.37e-01
Phosphorylation of the APC/C 18 4.07e-02 -2.79e-01 2.38e-01
Miscellaneous substrates 12 4.13e-02 3.40e-01 2.38e-01
VEGFR2 mediated vascular permeability 25 4.13e-02 2.36e-01 2.38e-01
Signaling by FGFR3 in disease 20 4.19e-02 2.63e-01 2.38e-01
Signaling by FGFR3 point mutants in cancer 20 4.19e-02 2.63e-01 2.38e-01
Vpu mediated degradation of CD4 43 4.20e-02 -1.79e-01 2.38e-01
Dectin-1 mediated noncanonical NF-kB signaling 54 4.20e-02 -1.60e-01 2.38e-01
Neddylation 213 4.21e-02 -8.09e-02 2.38e-01
Retinoid metabolism and transport 38 4.21e-02 1.91e-01 2.38e-01
COPI-mediated anterograde transport 75 4.36e-02 -1.35e-01 2.46e-01
Hedgehog ‘off’ state 89 4.44e-02 -1.23e-01 2.49e-01
Metabolism of polyamines 53 4.49e-02 -1.59e-01 2.50e-01
Cell junction organization 80 4.49e-02 1.30e-01 2.50e-01
Regulation of Apoptosis 45 4.56e-02 -1.72e-01 2.51e-01
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 43 4.59e-02 -1.76e-01 2.51e-01
p53-Independent DNA Damage Response 43 4.59e-02 -1.76e-01 2.51e-01
p53-Independent G1/S DNA damage checkpoint 43 4.59e-02 -1.76e-01 2.51e-01
Erythrocytes take up carbon dioxide and release oxygen 11 4.81e-02 3.44e-01 2.62e-01
O2/CO2 exchange in erythrocytes 11 4.81e-02 3.44e-01 2.62e-01
Apoptotic cleavage of cellular proteins 38 4.83e-02 1.85e-01 2.62e-01
Initial triggering of complement 28 4.86e-02 -2.15e-01 2.62e-01
Glycogen breakdown (glycogenolysis) 14 4.90e-02 -3.04e-01 2.63e-01
Transport to the Golgi and subsequent modification 149 4.91e-02 -9.35e-02 2.63e-01
Signaling by Hedgehog 123 5.01e-02 -1.02e-01 2.65e-01
Keratan sulfate degradation 12 5.02e-02 -3.26e-01 2.65e-01
COPII-mediated vesicle transport 61 5.05e-02 -1.45e-01 2.65e-01
FGFR3 ligand binding and activation 12 5.06e-02 3.26e-01 2.65e-01
FGFR3c ligand binding and activation 12 5.06e-02 3.26e-01 2.65e-01
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 47 5.09e-02 -1.65e-01 2.65e-01
Response of EIF2AK1 (HRI) to heme deficiency 14 5.09e-02 -3.01e-01 2.65e-01
Glycogen metabolism 24 5.10e-02 -2.30e-01 2.65e-01
Degradation of DVL 49 5.30e-02 -1.60e-01 2.75e-01
Nuclear Receptor transcription pathway 52 5.52e-02 1.54e-01 2.85e-01
Cytosolic tRNA aminoacylation 22 5.54e-02 2.36e-01 2.85e-01
Nephrin family interactions 20 5.60e-02 2.47e-01 2.87e-01
CDT1 association with the CDC6:ORC:origin complex 51 5.66e-02 -1.54e-01 2.87e-01
HS-GAG degradation 18 5.66e-02 2.60e-01 2.87e-01
Laminin interactions 23 5.67e-02 2.30e-01 2.87e-01
Inactivation of APC/C via direct inhibition of the APC/C complex 19 5.70e-02 -2.52e-01 2.87e-01
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 19 5.70e-02 -2.52e-01 2.87e-01
Regulation of TP53 Activity through Methylation 15 5.72e-02 -2.84e-01 2.87e-01
ABC transporters in lipid homeostasis 17 5.74e-02 2.66e-01 2.87e-01
HATs acetylate histones 74 5.77e-02 -1.28e-01 2.88e-01
Metabolism of cofactors 17 5.86e-02 2.65e-01 2.91e-01
Signaling by Leptin 10 6.07e-02 -3.43e-01 3.00e-01
Condensation of Prophase Chromosomes 16 6.14e-02 -2.70e-01 3.02e-01
Pre-NOTCH Processing in Golgi 18 6.25e-02 2.54e-01 3.07e-01
RHO GTPases Activate ROCKs 18 6.33e-02 2.53e-01 3.07e-01
Cytosolic iron-sulfur cluster assembly 12 6.34e-02 3.10e-01 3.07e-01
Synthesis of bile acids and bile salts via 27-hydroxycholesterol 11 6.36e-02 3.23e-01 3.07e-01
RUNX2 regulates osteoblast differentiation 22 6.36e-02 -2.29e-01 3.07e-01
Degradation of AXIN 46 6.37e-02 -1.58e-01 3.07e-01
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 56 6.43e-02 -1.43e-01 3.09e-01
Ras activation upon Ca2+ influx through NMDA receptor 18 6.46e-02 -2.52e-01 3.09e-01
Intrinsic Pathway for Apoptosis 44 6.47e-02 1.61e-01 3.09e-01
Signaling by SCF-KIT 41 6.57e-02 -1.66e-01 3.12e-01
Degradation of GLI2 by the proteasome 49 6.57e-02 -1.52e-01 3.12e-01
Pentose phosphate pathway 13 6.64e-02 -2.94e-01 3.14e-01
Defective B3GALT6 causes EDSP2 and SEMDJL1 19 6.68e-02 2.43e-01 3.15e-01
DNA Damage Recognition in GG-NER 36 6.74e-02 -1.76e-01 3.16e-01
A tetrasaccharide linker sequence is required for GAG synthesis 24 6.77e-02 2.15e-01 3.16e-01
Pyruvate metabolism 28 6.78e-02 1.99e-01 3.16e-01
Cell Cycle 579 6.83e-02 -4.45e-02 3.18e-01
Degradation of GLI1 by the proteasome 51 6.95e-02 -1.47e-01 3.22e-01
FCERI mediated MAPK activation 40 6.98e-02 -1.66e-01 3.22e-01
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 12 7.07e-02 3.01e-01 3.26e-01
Establishment of Sister Chromatid Cohesion 11 7.12e-02 -3.14e-01 3.27e-01
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 13 7.17e-02 2.89e-01 3.28e-01
Glycosphingolipid metabolism 40 7.37e-02 1.63e-01 3.34e-01
Crosslinking of collagen fibrils 10 7.37e-02 -3.27e-01 3.34e-01
Activation of BAD and translocation to mitochondria 14 7.39e-02 2.76e-01 3.34e-01
Cellular response to hypoxia 65 7.42e-02 -1.28e-01 3.34e-01
Cytokine Signaling in Immune system 750 7.43e-02 -3.85e-02 3.34e-01
DARPP-32 events 23 7.47e-02 -2.15e-01 3.35e-01
Gamma-carboxylation of protein precursors 10 7.57e-02 3.24e-01 3.37e-01
Defective B4GALT7 causes EDS, progeroid type 19 7.57e-02 2.35e-01 3.37e-01
Chromosome Maintenance 90 7.60e-02 -1.08e-01 3.38e-01
Biological oxidations 169 7.70e-02 7.90e-02 3.41e-01
ADP signalling through P2Y purinoceptor 12 18 7.75e-02 2.40e-01 3.42e-01
Transcription-Coupled Nucleotide Excision Repair (TC-NER) 72 7.83e-02 -1.20e-01 3.44e-01
Synaptic adhesion-like molecules 21 7.85e-02 -2.22e-01 3.44e-01
IKK complex recruitment mediated by RIP1 16 7.89e-02 -2.54e-01 3.45e-01
Switching of origins to a post-replicative state 81 8.02e-02 -1.13e-01 3.48e-01
Lysine catabolism 12 8.02e-02 2.92e-01 3.48e-01
Cell Cycle, Mitotic 460 8.03e-02 -4.77e-02 3.48e-01
RHO GTPases Activate Formins 116 8.05e-02 -9.40e-02 3.48e-01
FGFR1c ligand binding and activation 10 8.20e-02 3.18e-01 3.52e-01
Signaling by activated point mutants of FGFR1 10 8.20e-02 3.18e-01 3.52e-01
SIRT1 negatively regulates rRNA expression 12 8.24e-02 -2.90e-01 3.53e-01
Heme biosynthesis 12 8.29e-02 2.89e-01 3.53e-01
G-protein activation 24 8.33e-02 2.04e-01 3.53e-01
XBP1(S) activates chaperone genes 47 8.33e-02 1.46e-01 3.53e-01
YAP1- and WWTR1 (TAZ)-stimulated gene expression 14 8.37e-02 -2.67e-01 3.54e-01
FGFR2 alternative splicing 22 8.39e-02 -2.13e-01 3.54e-01
PECAM1 interactions 11 8.46e-02 -3.00e-01 3.55e-01
Translesion synthesis by POLK 15 8.48e-02 -2.57e-01 3.56e-01
Signaling by VEGF 97 8.58e-02 1.01e-01 3.59e-01
HIV Infection 207 8.64e-02 -6.92e-02 3.60e-01
Mitotic Telophase/Cytokinesis 13 8.66e-02 -2.75e-01 3.60e-01
Nucleotide Excision Repair 103 8.73e-02 -9.76e-02 3.60e-01
Acetylcholine binding and downstream events 11 8.76e-02 2.97e-01 3.60e-01
Postsynaptic nicotinic acetylcholine receptors 11 8.76e-02 2.97e-01 3.60e-01
Synthesis, secretion, and deacylation of Ghrelin 19 8.79e-02 -2.26e-01 3.60e-01
Innate Immune System 882 8.80e-02 -3.41e-02 3.60e-01
Synthesis of DNA 109 8.86e-02 -9.45e-02 3.61e-01
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins 11 8.89e-02 2.96e-01 3.62e-01
Ubiquitin-dependent degradation of Cyclin D 44 8.99e-02 -1.48e-01 3.65e-01
SARS-CoV Infections 131 9.17e-02 8.54e-02 3.70e-01
tRNA modification in the nucleus and cytosol 41 9.18e-02 -1.52e-01 3.70e-01
Constitutive Signaling by NOTCH1 HD Domain Mutants 13 9.49e-02 2.68e-01 3.80e-01
Signaling by NOTCH1 HD Domain Mutants in Cancer 13 9.49e-02 2.68e-01 3.80e-01
AUF1 (hnRNP D0) binds and destabilizes mRNA 46 9.53e-02 -1.42e-01 3.80e-01
Regulation of mRNA stability by proteins that bind AU-rich elements 78 9.59e-02 -1.09e-01 3.80e-01
Cell-Cell communication 111 9.60e-02 9.15e-02 3.80e-01
Mitotic Prometaphase 175 9.61e-02 -7.30e-02 3.80e-01
Extra-nuclear estrogen signaling 65 9.61e-02 1.19e-01 3.80e-01
Regulation of KIT signaling 16 9.64e-02 -2.40e-01 3.80e-01
GPVI-mediated activation cascade 31 9.66e-02 -1.72e-01 3.80e-01
NGF-stimulated transcription 37 9.83e-02 -1.57e-01 3.85e-01
Defective CFTR causes cystic fibrosis 53 9.85e-02 -1.31e-01 3.85e-01
DNA Replication 116 9.89e-02 -8.88e-02 3.85e-01
Platelet homeostasis 77 9.91e-02 1.09e-01 3.85e-01
Defensins 20 9.95e-02 2.13e-01 3.86e-01
Budding and maturation of HIV virion 24 1.00e-01 -1.94e-01 3.86e-01
Smooth Muscle Contraction 32 1.00e-01 1.68e-01 3.86e-01
Incretin synthesis, secretion, and inactivation 22 1.00e-01 -2.02e-01 3.86e-01
Trafficking and processing of endosomal TLR 12 1.02e-01 -2.73e-01 3.90e-01
Prolonged ERK activation events 13 1.04e-01 2.61e-01 3.96e-01
Reduction of cytosolic Ca++ levels 12 1.05e-01 2.71e-01 3.99e-01
SHC-mediated cascade:FGFR3 16 1.06e-01 2.34e-01 4.03e-01
Signaling by Retinoic Acid 35 1.06e-01 1.58e-01 4.04e-01
Aspartate and asparagine metabolism 10 1.07e-01 2.94e-01 4.04e-01
Lysosphingolipid and LPA receptors 13 1.07e-01 2.58e-01 4.05e-01
IRE1alpha activates chaperones 49 1.08e-01 1.33e-01 4.05e-01
Visual phototransduction 85 1.08e-01 1.01e-01 4.06e-01
MTOR signalling 37 1.10e-01 -1.52e-01 4.12e-01
ER Quality Control Compartment (ERQC) 18 1.12e-01 2.16e-01 4.18e-01
Heparan sulfate/heparin (HS-GAG) metabolism 46 1.13e-01 1.35e-01 4.19e-01
Cell surface interactions at the vascular wall 132 1.13e-01 8.00e-02 4.19e-01
S Phase 151 1.14e-01 -7.47e-02 4.20e-01
Early Phase of HIV Life Cycle 12 1.14e-01 -2.63e-01 4.22e-01
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 18 1.15e-01 -2.15e-01 4.22e-01
RHO GTPases activate PKNs 35 1.15e-01 1.54e-01 4.22e-01
Common Pathway of Fibrin Clot Formation 20 1.16e-01 2.03e-01 4.24e-01
VEGFA-VEGFR2 Pathway 88 1.18e-01 9.65e-02 4.30e-01
Defective B3GAT3 causes JDSSDHD 18 1.19e-01 2.12e-01 4.30e-01
Caspase activation via extrinsic apoptotic signalling pathway 20 1.19e-01 -2.01e-01 4.30e-01
Adenylate cyclase inhibitory pathway 14 1.19e-01 2.41e-01 4.30e-01
Regulation of RUNX2 expression and activity 63 1.20e-01 -1.13e-01 4.30e-01
SLC transporter disorders 92 1.20e-01 9.39e-02 4.30e-01
Leading Strand Synthesis 13 1.20e-01 -2.49e-01 4.30e-01
Polymerase switching 13 1.20e-01 -2.49e-01 4.30e-01
Formation of ATP by chemiosmotic coupling 13 1.21e-01 2.48e-01 4.35e-01
Ion homeostasis 45 1.22e-01 1.33e-01 4.37e-01
Carboxyterminal post-translational modifications of tubulin 30 1.23e-01 -1.63e-01 4.37e-01
Signaling by NOTCH4 72 1.23e-01 -1.05e-01 4.38e-01
Negative regulation of NMDA receptor-mediated neuronal transmission 20 1.24e-01 -1.99e-01 4.40e-01
Translesion synthesis by REV1 14 1.25e-01 -2.37e-01 4.44e-01
Platelet calcium homeostasis 27 1.26e-01 1.70e-01 4.44e-01
Global Genome Nucleotide Excision Repair (GG-NER) 79 1.27e-01 -9.93e-02 4.48e-01
PI Metabolism 77 1.31e-01 9.97e-02 4.59e-01
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 40 1.32e-01 -1.38e-01 4.61e-01
Processing of Capped Intron-Containing Pre-mRNA 223 1.33e-01 -5.85e-02 4.61e-01
Post NMDA receptor activation events 57 1.33e-01 -1.15e-01 4.61e-01
Activation of NMDA receptors and postsynaptic events 68 1.34e-01 -1.05e-01 4.61e-01
Acyl chain remodelling of PS 20 1.34e-01 -1.94e-01 4.61e-01
CTLA4 inhibitory signaling 21 1.34e-01 -1.89e-01 4.61e-01
VLDLR internalisation and degradation 12 1.34e-01 2.50e-01 4.61e-01
Signaling by Insulin receptor 67 1.34e-01 1.06e-01 4.61e-01
Retrograde neurotrophin signalling 14 1.35e-01 2.31e-01 4.62e-01
RHO GTPases activate KTN1 10 1.35e-01 2.73e-01 4.62e-01
Signaling by ERBB2 in Cancer 22 1.35e-01 1.84e-01 4.62e-01
DAP12 signaling 27 1.36e-01 -1.66e-01 4.63e-01
EGR2 and SOX10-mediated initiation of Schwann cell myelination 24 1.37e-01 1.75e-01 4.63e-01
CD22 mediated BCR regulation 19 1.37e-01 -1.97e-01 4.63e-01
IRS-related events triggered by IGF1R 45 1.37e-01 1.28e-01 4.63e-01
Nuclear Envelope (NE) Reassembly 62 1.37e-01 1.09e-01 4.63e-01
Muscle contraction 166 1.37e-01 6.69e-02 4.63e-01
Activation of Matrix Metalloproteinases 26 1.38e-01 -1.68e-01 4.63e-01
SUMOylation of DNA methylation proteins 15 1.39e-01 2.21e-01 4.63e-01
Phospholipase C-mediated cascade: FGFR1 14 1.39e-01 2.28e-01 4.63e-01
Negative regulation of FGFR3 signaling 24 1.39e-01 1.74e-01 4.63e-01
DNA Repair 265 1.40e-01 -5.28e-02 4.63e-01
TGF-beta receptor signaling activates SMADs 27 1.40e-01 1.64e-01 4.63e-01
Asparagine N-linked glycosylation 259 1.40e-01 -5.33e-02 4.63e-01
NOTCH4 Activation and Transmission of Signal to the Nucleus 11 1.40e-01 2.57e-01 4.63e-01
PKMTs methylate histone lysines 40 1.41e-01 1.34e-01 4.63e-01
E2F mediated regulation of DNA replication 21 1.42e-01 -1.85e-01 4.63e-01
Synthesis of PIPs at the plasma membrane 49 1.42e-01 1.21e-01 4.63e-01
Signaling by Nuclear Receptors 219 1.42e-01 5.77e-02 4.63e-01
Frs2-mediated activation 11 1.42e-01 2.55e-01 4.63e-01
Metabolism of non-coding RNA 51 1.43e-01 -1.19e-01 4.63e-01
snRNP Assembly 51 1.43e-01 -1.19e-01 4.63e-01
RHO GTPases activate PAKs 20 1.43e-01 1.89e-01 4.63e-01
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 28 1.43e-01 -1.60e-01 4.63e-01
HIV Life Cycle 134 1.44e-01 -7.32e-02 4.63e-01
RHO GTPases activate CIT 18 1.44e-01 1.99e-01 4.63e-01
Potential therapeutics for SARS 72 1.44e-01 9.96e-02 4.63e-01
Metabolism of steroid hormones 27 1.45e-01 1.62e-01 4.63e-01
Signaling by RAF1 mutants 36 1.45e-01 -1.40e-01 4.64e-01
Eicosanoids 12 1.46e-01 2.43e-01 4.65e-01
Presynaptic depolarization and calcium channel opening 11 1.46e-01 -2.53e-01 4.66e-01
The canonical retinoid cycle in rods (twilight vision) 21 1.47e-01 1.83e-01 4.68e-01
Calnexin/calreticulin cycle 23 1.49e-01 1.74e-01 4.70e-01
Rap1 signalling 14 1.49e-01 2.23e-01 4.70e-01
Transcriptional regulation of granulopoiesis 34 1.50e-01 -1.43e-01 4.74e-01
Energy dependent regulation of mTOR by LKB1-AMPK 27 1.51e-01 -1.60e-01 4.75e-01
Downstream signaling of activated FGFR3 23 1.52e-01 1.73e-01 4.75e-01
Transport of organic anions 12 1.52e-01 2.39e-01 4.75e-01
G alpha (q) signalling events 180 1.53e-01 6.19e-02 4.75e-01
Sialic acid metabolism 30 1.53e-01 1.51e-01 4.75e-01
p130Cas linkage to MAPK signaling for integrins 15 1.54e-01 -2.13e-01 4.75e-01
GRB2:SOS provides linkage to MAPK signaling for Integrins 15 1.54e-01 -2.12e-01 4.75e-01
Signaling by Non-Receptor Tyrosine Kinases 49 1.55e-01 1.18e-01 4.75e-01
Signaling by PTK6 49 1.55e-01 1.18e-01 4.75e-01
Activation of GABAB receptors 36 1.56e-01 1.37e-01 4.75e-01
GABA B receptor activation 36 1.56e-01 1.37e-01 4.75e-01
Plasma lipoprotein assembly, remodeling, and clearance 66 1.56e-01 1.01e-01 4.75e-01
Gene Silencing by RNA 77 1.56e-01 -9.36e-02 4.75e-01
Anchoring of the basal body to the plasma membrane 91 1.56e-01 8.60e-02 4.75e-01
Ub-specific processing proteases 146 1.57e-01 -6.80e-02 4.75e-01
Regulation of HSF1-mediated heat shock response 74 1.57e-01 9.53e-02 4.75e-01
mRNA Splicing - Minor Pathway 47 1.57e-01 -1.19e-01 4.75e-01
PI-3K cascade:FGFR1 19 1.57e-01 1.87e-01 4.75e-01
Endosomal Sorting Complex Required For Transport (ESCRT) 27 1.57e-01 -1.57e-01 4.75e-01
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 19 1.57e-01 1.87e-01 4.75e-01
Hh mutants that don’t undergo autocatalytic processing are degraded by ERAD 48 1.58e-01 -1.18e-01 4.75e-01
UCH proteinases 77 1.59e-01 -9.29e-02 4.77e-01
Adherens junctions interactions 31 1.60e-01 1.46e-01 4.79e-01
Cyclin E associated events during G1/S transition 76 1.61e-01 -9.30e-02 4.83e-01
LGI-ADAM interactions 10 1.62e-01 -2.55e-01 4.83e-01
IGF1R signaling cascade 46 1.62e-01 1.19e-01 4.83e-01
Orc1 removal from chromatin 63 1.63e-01 -1.02e-01 4.84e-01
Gamma carboxylation, hypusine formation and arylsulfatase activation 37 1.67e-01 1.31e-01 4.95e-01
Regulation of beta-cell development 36 1.68e-01 1.33e-01 4.95e-01
Metabolism of amino acids and derivatives 317 1.68e-01 -4.52e-02 4.95e-01
Signaling by FGFR1 41 1.68e-01 1.24e-01 4.95e-01
Signal Transduction 2155 1.68e-01 1.84e-02 4.95e-01
Disassembly of the destruction complex and recruitment of AXIN to the membrane 28 1.69e-01 1.50e-01 4.95e-01
Metabolism of proteins 1732 1.70e-01 -2.01e-02 4.95e-01
Eicosanoid ligand-binding receptors 11 1.70e-01 -2.39e-01 4.95e-01
Activation of HOX genes during differentiation 59 1.70e-01 -1.03e-01 4.95e-01
Activation of anterior HOX genes in hindbrain development during early embryogenesis 59 1.70e-01 -1.03e-01 4.95e-01
Degradation of beta-catenin by the destruction complex 75 1.71e-01 -9.15e-02 4.95e-01
mTORC1-mediated signalling 21 1.71e-01 -1.73e-01 4.95e-01
Transferrin endocytosis and recycling 26 1.71e-01 1.55e-01 4.95e-01
Phospholipase C-mediated cascade; FGFR4 13 1.71e-01 2.19e-01 4.95e-01
Late endosomal microautophagy 26 1.72e-01 -1.55e-01 4.95e-01
Inhibition of DNA recombination at telomere 22 1.72e-01 -1.68e-01 4.95e-01
Biosynthesis of specialized proresolving mediators (SPMs) 17 1.74e-01 -1.91e-01 4.98e-01
Caspase activation via Death Receptors in the presence of ligand 10 1.74e-01 -2.48e-01 4.99e-01
Condensation of Prometaphase Chromosomes 10 1.76e-01 -2.47e-01 5.02e-01
Xenobiotics 20 1.77e-01 1.74e-01 5.06e-01
Glutathione conjugation 28 1.78e-01 -1.47e-01 5.06e-01
PI3K Cascade 39 1.79e-01 1.24e-01 5.08e-01
Platelet sensitization by LDL 16 1.79e-01 -1.94e-01 5.08e-01
FGFR1 ligand binding and activation 13 1.80e-01 2.15e-01 5.08e-01
Purine catabolism 15 1.80e-01 2.00e-01 5.08e-01
Antigen processing: Ubiquitination & Proteasome degradation 277 1.80e-01 -4.69e-02 5.08e-01
Mitochondrial iron-sulfur cluster biogenesis 11 1.81e-01 2.33e-01 5.09e-01
RIP-mediated NFkB activation via ZBP1 15 1.82e-01 1.99e-01 5.09e-01
RUNX2 regulates bone development 28 1.82e-01 -1.46e-01 5.09e-01
p75 NTR receptor-mediated signalling 89 1.82e-01 8.19e-02 5.09e-01
FGFR2 ligand binding and activation 17 1.82e-01 1.87e-01 5.09e-01
Processing of DNA double-strand break ends 56 1.83e-01 -1.03e-01 5.09e-01
RET signaling 38 1.83e-01 1.25e-01 5.09e-01
Rab regulation of trafficking 115 1.83e-01 7.19e-02 5.09e-01
RNA Polymerase III Transcription Initiation From Type 1 Promoter 24 1.84e-01 -1.57e-01 5.10e-01
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 25 1.85e-01 -1.53e-01 5.10e-01
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) 19 1.85e-01 -1.76e-01 5.10e-01
Regulation of localization of FOXO transcription factors 11 1.85e-01 2.31e-01 5.10e-01
Downregulation of TGF-beta receptor signaling 22 1.86e-01 1.63e-01 5.10e-01
RNA Polymerase I Promoter Escape 32 1.86e-01 -1.35e-01 5.10e-01
DNA Double-Strand Break Repair 119 1.87e-01 -7.02e-02 5.10e-01
Phospholipase C-mediated cascade; FGFR2 16 1.87e-01 1.91e-01 5.10e-01
RNA Polymerase II Pre-transcription Events 74 1.88e-01 -8.85e-02 5.11e-01
Interleukin-4 and Interleukin-13 signaling 95 1.89e-01 -7.81e-02 5.11e-01
RMTs methylate histone arginines 33 1.89e-01 -1.32e-01 5.11e-01
Metalloprotease DUBs 15 1.89e-01 -1.96e-01 5.11e-01
Fatty acids 14 1.90e-01 2.03e-01 5.11e-01
Insulin receptor recycling 22 1.90e-01 1.62e-01 5.11e-01
PI-3K cascade:FGFR4 18 1.90e-01 1.79e-01 5.11e-01
ATF6 (ATF6-alpha) activates chaperones 12 1.90e-01 -2.18e-01 5.12e-01
Ca-dependent events 34 1.91e-01 -1.30e-01 5.13e-01
Neurexins and neuroligins 53 1.92e-01 1.04e-01 5.13e-01
Regulation of TP53 Activity through Phosphorylation 81 1.92e-01 -8.39e-02 5.14e-01
Receptor-type tyrosine-protein phosphatases 19 1.93e-01 1.73e-01 5.14e-01
AKT phosphorylates targets in the cytosol 14 1.93e-01 2.01e-01 5.14e-01
mRNA Splicing 172 1.94e-01 -5.75e-02 5.16e-01
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 47 1.95e-01 1.09e-01 5.17e-01
RNA Polymerase III Transcription Initiation From Type 2 Promoter 23 1.97e-01 -1.55e-01 5.20e-01
Regulation of gene expression in beta cells 20 1.97e-01 1.67e-01 5.20e-01
PI-3K cascade:FGFR2 21 1.97e-01 1.63e-01 5.20e-01
Plasma lipoprotein remodeling 29 1.99e-01 1.38e-01 5.23e-01
FGFR1 mutant receptor activation 29 2.00e-01 1.38e-01 5.25e-01
FCERI mediated Ca+2 mobilization 41 2.00e-01 -1.16e-01 5.25e-01
Receptor Mediated Mitophagy 11 2.01e-01 -2.23e-01 5.25e-01
CaM pathway 32 2.01e-01 -1.31e-01 5.25e-01
Calmodulin induced events 32 2.01e-01 -1.31e-01 5.25e-01
Regulation of FZD by ubiquitination 16 2.02e-01 1.84e-01 5.25e-01
Metabolism of water-soluble vitamins and cofactors 111 2.02e-01 7.01e-02 5.25e-01
Triglyceride catabolism 21 2.02e-01 1.61e-01 5.25e-01
Cohesin Loading onto Chromatin 10 2.05e-01 -2.31e-01 5.31e-01
COPI-independent Golgi-to-ER retrograde traffic 32 2.05e-01 -1.29e-01 5.31e-01
Assembly of active LPL and LIPC lipase complexes 18 2.06e-01 1.72e-01 5.31e-01
N-glycan trimming in the ER and Calnexin/Calreticulin cycle 32 2.07e-01 1.29e-01 5.31e-01
Synthesis of PIPs at the early endosome membrane 16 2.07e-01 1.82e-01 5.31e-01
Regulated proteolysis of p75NTR 11 2.07e-01 2.20e-01 5.31e-01
Regulation of TP53 Activity through Association with Co-factors 12 2.08e-01 2.10e-01 5.32e-01
Biosynthesis of DHA-derived SPMs 15 2.09e-01 -1.87e-01 5.35e-01
RHO GTPases Activate NADPH Oxidases 22 2.10e-01 -1.54e-01 5.37e-01
MHC class II antigen presentation 90 2.11e-01 -7.63e-02 5.37e-01
Caspase-mediated cleavage of cytoskeletal proteins 12 2.12e-01 2.08e-01 5.37e-01
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 13 2.13e-01 2.00e-01 5.37e-01
Class I peroxisomal membrane protein import 18 2.14e-01 1.69e-01 5.37e-01
ROS and RNS production in phagocytes 31 2.14e-01 1.29e-01 5.37e-01
Disorders of Developmental Biology 13 2.14e-01 1.99e-01 5.37e-01
Disorders of Nervous System Development 13 2.14e-01 1.99e-01 5.37e-01
Loss of function of MECP2 in Rett syndrome 13 2.14e-01 1.99e-01 5.37e-01
Pervasive developmental disorders 13 2.14e-01 1.99e-01 5.37e-01
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 12 2.14e-01 -2.07e-01 5.37e-01
Cardiac conduction 109 2.15e-01 6.87e-02 5.39e-01
Meiotic recombination 29 2.16e-01 -1.33e-01 5.40e-01
Reversible hydration of carbon dioxide 12 2.18e-01 2.06e-01 5.43e-01
Binding and Uptake of Ligands by Scavenger Receptors 49 2.19e-01 -1.02e-01 5.45e-01
Inositol phosphate metabolism 45 2.20e-01 1.06e-01 5.46e-01
Signaling by WNT in cancer 29 2.20e-01 1.31e-01 5.47e-01
FGFR4 ligand binding and activation 12 2.22e-01 2.04e-01 5.49e-01
RAS processing 18 2.23e-01 1.66e-01 5.51e-01
The NLRP3 inflammasome 15 2.23e-01 -1.82e-01 5.51e-01
Dissolution of Fibrin Clot 11 2.24e-01 -2.12e-01 5.51e-01
NOD1/2 Signaling Pathway 30 2.24e-01 -1.28e-01 5.51e-01
Signaling by FGFR3 34 2.25e-01 1.20e-01 5.51e-01
Protein folding 88 2.25e-01 7.48e-02 5.51e-01
FGFRL1 modulation of FGFR1 signaling 10 2.25e-01 2.21e-01 5.51e-01
Apoptotic factor-mediated response 13 2.26e-01 1.94e-01 5.51e-01
G beta:gamma signalling through PLC beta 16 2.27e-01 1.75e-01 5.51e-01
EGFR downregulation 29 2.27e-01 1.30e-01 5.51e-01
Other semaphorin interactions 19 2.27e-01 -1.60e-01 5.51e-01
Unwinding of DNA 12 2.28e-01 2.01e-01 5.51e-01
PI3K events in ERBB2 signaling 15 2.28e-01 1.80e-01 5.51e-01
Cyclin A:Cdk2-associated events at S phase entry 78 2.28e-01 -7.90e-02 5.51e-01
Transcriptional regulation by small RNAs 47 2.29e-01 -1.01e-01 5.53e-01
Signal transduction by L1 20 2.31e-01 1.55e-01 5.55e-01
Cellular hexose transport 19 2.32e-01 1.58e-01 5.57e-01
Tryptophan catabolism 14 2.32e-01 1.84e-01 5.57e-01
Signaling by ERBB2 KD Mutants 21 2.33e-01 1.50e-01 5.57e-01
Chaperone Mediated Autophagy 14 2.34e-01 -1.84e-01 5.57e-01
Signaling by FGFR1 in disease 35 2.34e-01 1.16e-01 5.57e-01
Oncogenic MAPK signaling 74 2.34e-01 8.00e-02 5.57e-01
Removal of the Flap Intermediate from the C-strand 16 2.34e-01 1.72e-01 5.57e-01
Glutamate Neurotransmitter Release Cycle 23 2.34e-01 1.43e-01 5.57e-01
Synthesis of PA 36 2.35e-01 1.14e-01 5.57e-01
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors 11 2.36e-01 2.06e-01 5.58e-01
p38MAPK events 12 2.37e-01 -1.97e-01 5.58e-01
Activated point mutants of FGFR2 15 2.37e-01 1.77e-01 5.58e-01
Late Phase of HIV Life Cycle 123 2.37e-01 -6.18e-02 5.58e-01
Golgi-to-ER retrograde transport 109 2.38e-01 -6.55e-02 5.59e-01
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 25 2.40e-01 -1.36e-01 5.64e-01
Polymerase switching on the C-strand of the telomere 25 2.41e-01 -1.36e-01 5.64e-01
Prefoldin mediated transfer of substrate to CCT/TriC 22 2.41e-01 -1.44e-01 5.64e-01
RNA Polymerase I Promoter Clearance 49 2.42e-01 -9.66e-02 5.64e-01
RNA Polymerase I Transcription 49 2.42e-01 -9.66e-02 5.64e-01
Thrombin signalling through proteinase activated receptors (PARs) 24 2.42e-01 1.38e-01 5.64e-01
Na+/Cl- dependent neurotransmitter transporters 17 2.45e-01 1.63e-01 5.68e-01
Nonhomologous End-Joining (NHEJ) 33 2.46e-01 -1.17e-01 5.68e-01
Deactivation of the beta-catenin transactivating complex 35 2.46e-01 1.13e-01 5.68e-01
Protein-protein interactions at synapses 83 2.46e-01 7.37e-02 5.68e-01
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer’s disease models 17 2.46e-01 1.62e-01 5.68e-01
Neurodegenerative Diseases 17 2.46e-01 1.62e-01 5.68e-01
Aquaporin-mediated transport 43 2.47e-01 1.02e-01 5.68e-01
Translesion Synthesis by POLH 15 2.47e-01 -1.72e-01 5.68e-01
B-WICH complex positively regulates rRNA expression 32 2.48e-01 -1.18e-01 5.68e-01
Non-integrin membrane-ECM interactions 41 2.48e-01 1.04e-01 5.68e-01
Chaperonin-mediated protein folding 82 2.50e-01 7.36e-02 5.71e-01
Golgi Cisternae Pericentriolar Stack Reorganization 11 2.52e-01 -1.99e-01 5.75e-01
IRS-mediated signalling 42 2.52e-01 1.02e-01 5.75e-01
Cytosolic sensors of pathogen-associated DNA 53 2.53e-01 -9.08e-02 5.75e-01
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 37 2.53e-01 1.09e-01 5.75e-01
Golgi Associated Vesicle Biogenesis 54 2.54e-01 -8.98e-02 5.75e-01
Translesion synthesis by POLI 15 2.58e-01 -1.69e-01 5.84e-01
TP53 Regulates Transcription of Caspase Activators and Caspases 10 2.59e-01 -2.06e-01 5.84e-01
Processive synthesis on the C-strand of the telomere 18 2.59e-01 1.54e-01 5.84e-01
Endogenous sterols 24 2.60e-01 1.33e-01 5.84e-01
Other interleukin signaling 21 2.60e-01 -1.42e-01 5.84e-01
Plasma lipoprotein clearance 32 2.61e-01 1.15e-01 5.87e-01
Toll-like Receptor Cascades 134 2.62e-01 -5.62e-02 5.87e-01
Signaling by ERBB2 ECD mutants 13 2.62e-01 1.80e-01 5.87e-01
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 48 2.62e-01 -9.35e-02 5.87e-01
Diseases of programmed cell death 23 2.63e-01 1.35e-01 5.87e-01
NOTCH1 Intracellular Domain Regulates Transcription 41 2.64e-01 -1.01e-01 5.88e-01
Growth hormone receptor signaling 22 2.65e-01 -1.37e-01 5.89e-01
Signaling by GPCR 734 2.66e-01 2.42e-02 5.91e-01
Uptake and actions of bacterial toxins 25 2.68e-01 1.28e-01 5.93e-01
Senescence-Associated Secretory Phenotype (SASP) 47 2.71e-01 -9.29e-02 5.98e-01
Negative regulation of MAPK pathway 38 2.71e-01 1.03e-01 5.98e-01
Formation of the beta-catenin:TCF transactivating complex 33 2.71e-01 -1.11e-01 5.98e-01
NRAGE signals death through JNK 54 2.71e-01 8.66e-02 5.98e-01
Downregulation of ERBB2 signaling 24 2.73e-01 1.29e-01 5.98e-01
Signaling by NOTCH3 42 2.73e-01 9.78e-02 5.98e-01
Post-translational protein modification 1214 2.75e-01 -1.88e-02 5.98e-01
Insulin receptor signalling cascade 47 2.75e-01 9.21e-02 5.98e-01
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 39 2.76e-01 1.01e-01 5.98e-01
ESR-mediated signaling 153 2.76e-01 5.11e-02 5.98e-01
Thromboxane signalling through TP receptor 18 2.76e-01 1.48e-01 5.98e-01
N-glycan antennae elongation in the medial/trans-Golgi 21 2.76e-01 1.37e-01 5.98e-01
FRS-mediated FGFR3 signaling 18 2.77e-01 1.48e-01 5.98e-01
HCMV Infection 80 2.77e-01 -7.03e-02 5.98e-01
Diseases associated with O-glycosylation of proteins 56 2.78e-01 -8.39e-02 5.98e-01
HS-GAG biosynthesis 26 2.78e-01 1.23e-01 5.98e-01
Pre-NOTCH Transcription and Translation 39 2.79e-01 -1.00e-01 5.98e-01
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 10 2.79e-01 1.98e-01 5.98e-01
FGFR2c ligand binding and activation 12 2.79e-01 1.80e-01 5.98e-01
G2/M Checkpoints 120 2.80e-01 -5.72e-02 5.98e-01
CRMPs in Sema3A signaling 15 2.80e-01 -1.61e-01 5.98e-01
Meiosis 58 2.81e-01 -8.19e-02 5.98e-01
HIV Transcription Initiation 42 2.82e-01 -9.60e-02 5.98e-01
RNA Polymerase II HIV Promoter Escape 42 2.82e-01 -9.60e-02 5.98e-01
RNA Polymerase II Promoter Escape 42 2.82e-01 -9.60e-02 5.98e-01
RNA Polymerase II Transcription Initiation 42 2.82e-01 -9.60e-02 5.98e-01
RNA Polymerase II Transcription Initiation And Promoter Clearance 42 2.82e-01 -9.60e-02 5.98e-01
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 42 2.82e-01 -9.60e-02 5.98e-01
SARS-CoV-1 Infection 44 2.84e-01 9.34e-02 6.03e-01
NOTCH3 Activation and Transmission of Signal to the Nucleus 22 2.86e-01 1.32e-01 6.04e-01
Developmental Biology 826 2.86e-01 -2.20e-02 6.04e-01
RA biosynthesis pathway 16 2.87e-01 -1.54e-01 6.06e-01
Diseases of carbohydrate metabolism 26 2.88e-01 1.20e-01 6.07e-01
Nucleobase biosynthesis 12 2.90e-01 1.76e-01 6.11e-01
Intra-Golgi and retrograde Golgi-to-ER traffic 170 2.91e-01 -4.70e-02 6.12e-01
Host Interactions of HIV factors 115 2.92e-01 -5.69e-02 6.12e-01
Nuclear Events (kinase and transcription factor activation) 57 2.94e-01 -8.04e-02 6.12e-01
Paradoxical activation of RAF signaling by kinase inactive BRAF 39 2.94e-01 -9.71e-02 6.12e-01
Signaling by RAS mutants 39 2.94e-01 -9.71e-02 6.12e-01
Signaling by moderate kinase activity BRAF mutants 39 2.94e-01 -9.71e-02 6.12e-01
Signaling downstream of RAS mutants 39 2.94e-01 -9.71e-02 6.12e-01
Transcriptional regulation by RUNX1 164 2.94e-01 -4.75e-02 6.12e-01
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 13 2.95e-01 1.68e-01 6.12e-01
Metabolism of Angiotensinogen to Angiotensins 17 2.96e-01 1.47e-01 6.12e-01
RAB GEFs exchange GTP for GDP on RABs 84 2.96e-01 6.60e-02 6.12e-01
ERKs are inactivated 11 2.96e-01 1.82e-01 6.12e-01
Signaling by KIT in disease 19 2.97e-01 -1.38e-01 6.12e-01
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants 19 2.97e-01 -1.38e-01 6.12e-01
N-Glycan antennae elongation 13 2.98e-01 1.67e-01 6.13e-01
Signaling by FGFR in disease 57 2.98e-01 7.96e-02 6.14e-01
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 11 2.99e-01 1.81e-01 6.14e-01
RIPK1-mediated regulated necrosis 22 3.00e-01 -1.28e-01 6.14e-01
Regulated Necrosis 22 3.00e-01 -1.28e-01 6.14e-01
Regulation of necroptotic cell death 22 3.00e-01 -1.28e-01 6.14e-01
Sema3A PAK dependent Axon repulsion 15 3.01e-01 -1.54e-01 6.14e-01
G alpha (z) signalling events 44 3.02e-01 8.99e-02 6.16e-01
Hh mutants abrogate ligand secretion 51 3.03e-01 -8.34e-02 6.16e-01
Signaling by NODAL 18 3.04e-01 -1.40e-01 6.18e-01
CD209 (DC-SIGN) signaling 18 3.06e-01 -1.39e-01 6.21e-01
Regulation of TP53 Activity 144 3.07e-01 -4.94e-02 6.22e-01
Synthesis of Leukotrienes (LT) and Eoxins (EX) 21 3.08e-01 1.28e-01 6.24e-01
Signal amplification 27 3.10e-01 1.13e-01 6.25e-01
Transcription of the HIV genome 63 3.13e-01 -7.35e-02 6.29e-01
Cilium Assembly 175 3.14e-01 4.42e-02 6.29e-01
Downstream signaling of activated FGFR1 28 3.14e-01 1.10e-01 6.29e-01
Synthesis of active ubiquitin: roles of E1 and E2 enzymes 25 3.15e-01 -1.16e-01 6.29e-01
TP53 Regulates Metabolic Genes 78 3.15e-01 6.59e-02 6.29e-01
PERK regulates gene expression 30 3.15e-01 -1.06e-01 6.29e-01
Formation of RNA Pol II elongation complex 54 3.16e-01 -7.90e-02 6.29e-01
RNA Polymerase II Transcription Elongation 54 3.16e-01 -7.90e-02 6.29e-01
G beta:gamma signalling through PI3Kgamma 21 3.16e-01 1.26e-01 6.29e-01
TICAM1, RIP1-mediated IKK complex recruitment 14 3.16e-01 -1.55e-01 6.29e-01
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 12 3.16e-01 1.67e-01 6.29e-01
Suppression of phagosomal maturation 11 3.18e-01 -1.74e-01 6.31e-01
Telomere Maintenance 65 3.18e-01 -7.16e-02 6.31e-01
Assembly of the pre-replicative complex 60 3.19e-01 -7.45e-02 6.31e-01
Cellular response to heat stress 90 3.20e-01 6.07e-02 6.32e-01
Cargo concentration in the ER 29 3.20e-01 -1.07e-01 6.32e-01
ISG15 antiviral mechanism 66 3.21e-01 -7.07e-02 6.32e-01
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 16 3.22e-01 -1.43e-01 6.34e-01
Transcriptional regulation of white adipocyte differentiation 79 3.23e-01 -6.43e-02 6.36e-01
MASTL Facilitates Mitotic Progression 10 3.25e-01 -1.80e-01 6.39e-01
RNA Polymerase III Transcription Initiation 32 3.26e-01 -1.00e-01 6.39e-01
Synthesis of PE 13 3.27e-01 1.57e-01 6.39e-01
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression 18 3.28e-01 -1.33e-01 6.39e-01
TBC/RABGAPs 43 3.28e-01 8.63e-02 6.39e-01
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 86 3.28e-01 -6.11e-02 6.39e-01
NCAM signaling for neurite out-growth 50 3.28e-01 7.99e-02 6.40e-01
Neurotransmitter release cycle 47 3.30e-01 8.22e-02 6.41e-01
Sulfur amino acid metabolism 24 3.30e-01 1.15e-01 6.41e-01
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 17 3.31e-01 -1.36e-01 6.42e-01
Cell-cell junction organization 56 3.33e-01 7.48e-02 6.45e-01
Vesicle-mediated transport 608 3.34e-01 -2.31e-02 6.45e-01
Platelet degranulation 120 3.34e-01 5.11e-02 6.45e-01
E3 ubiquitin ligases ubiquitinate target proteins 40 3.36e-01 -8.80e-02 6.47e-01
G alpha (i) signalling events 331 3.38e-01 3.07e-02 6.51e-01
Regulation of PTEN stability and activity 61 3.38e-01 -7.09e-02 6.51e-01
Metabolism of amine-derived hormones 15 3.39e-01 -1.43e-01 6.51e-01
SHC-mediated cascade:FGFR1 18 3.40e-01 1.30e-01 6.51e-01
Zinc transporters 15 3.41e-01 -1.42e-01 6.51e-01
ADP signalling through P2Y purinoceptor 1 20 3.41e-01 1.23e-01 6.51e-01
RNA polymerase II transcribes snRNA genes 68 3.41e-01 -6.68e-02 6.51e-01
Synthesis of IP2, IP, and Ins in the cytosol 13 3.42e-01 1.52e-01 6.51e-01
Glucose metabolism 86 3.42e-01 5.93e-02 6.51e-01
Negative regulation of FGFR1 signaling 26 3.45e-01 1.07e-01 6.56e-01
Regulation of IFNG signaling 13 3.45e-01 -1.51e-01 6.56e-01
SARS-CoV-2 Infection 61 3.46e-01 6.98e-02 6.56e-01
Negative regulation of the PI3K/AKT network 104 3.47e-01 5.34e-02 6.56e-01
mRNA Splicing - Major Pathway 164 3.47e-01 -4.26e-02 6.56e-01
Dermatan sulfate biosynthesis 11 3.48e-01 -1.64e-01 6.56e-01
Death Receptor Signalling 125 3.48e-01 4.87e-02 6.56e-01
trans-Golgi Network Vesicle Budding 69 3.48e-01 -6.53e-02 6.56e-01
Formation of tubulin folding intermediates by CCT/TriC 20 3.49e-01 -1.21e-01 6.57e-01
GPCR ligand binding 362 3.50e-01 2.87e-02 6.58e-01
RNA Polymerase II Transcription Termination 61 3.51e-01 -6.91e-02 6.58e-01
Presynaptic function of Kainate receptors 17 3.51e-01 1.31e-01 6.58e-01
mRNA decay by 3’ to 5’ exoribonuclease 15 3.51e-01 -1.39e-01 6.58e-01
Postmitotic nuclear pore complex (NPC) reformation 25 3.55e-01 1.07e-01 6.62e-01
Antimicrobial peptides 48 3.55e-01 7.72e-02 6.62e-01
VEGFR2 mediated cell proliferation 18 3.57e-01 1.25e-01 6.66e-01
Dual incision in TC-NER 59 3.58e-01 -6.92e-02 6.66e-01
FCGR3A-mediated IL10 synthesis 50 3.59e-01 -7.50e-02 6.66e-01
TRAF6-mediated induction of TAK1 complex within TLR4 complex 11 3.59e-01 -1.60e-01 6.66e-01
Defective EXT1 causes exostoses 1, TRPS2 and CHDS 13 3.59e-01 1.47e-01 6.66e-01
Defective EXT2 causes exostoses 2 13 3.59e-01 1.47e-01 6.66e-01
Cell death signalling via NRAGE, NRIF and NADE 69 3.65e-01 6.31e-02 6.74e-01
Arachidonic acid metabolism 51 3.65e-01 7.34e-02 6.74e-01
Negative regulation of MET activity 19 3.66e-01 -1.20e-01 6.76e-01
ATF6 (ATF6-alpha) activates chaperone genes 10 3.67e-01 -1.65e-01 6.77e-01
GPCR downstream signalling 670 3.69e-01 2.05e-02 6.79e-01
Interleukin-1 family signaling 124 3.72e-01 -4.65e-02 6.82e-01
Molecules associated with elastic fibres 27 3.73e-01 9.91e-02 6.82e-01
Selective autophagy 52 3.73e-01 -7.14e-02 6.82e-01
HDACs deacetylate histones 30 3.73e-01 9.39e-02 6.82e-01
Defects in vitamin and cofactor metabolism 21 3.73e-01 1.12e-01 6.82e-01
Synthesis of PIPs at the late endosome membrane 11 3.73e-01 1.55e-01 6.82e-01
Acetylcholine Neurotransmitter Release Cycle 15 3.74e-01 1.33e-01 6.82e-01
Regulation of lipid metabolism by PPARalpha 115 3.74e-01 4.80e-02 6.82e-01
HCMV Late Events 52 3.78e-01 -7.08e-02 6.87e-01
Folding of actin by CCT/TriC 10 3.79e-01 -1.61e-01 6.88e-01
Nicotinamide salvaging 18 3.80e-01 1.20e-01 6.88e-01
Lysosome Vesicle Biogenesis 33 3.81e-01 8.81e-02 6.91e-01
Axon guidance 470 3.82e-01 -2.36e-02 6.91e-01
TRP channels 24 3.83e-01 -1.03e-01 6.91e-01
Fanconi Anemia Pathway 32 3.83e-01 -8.92e-02 6.91e-01
DNA Replication Pre-Initiation 76 3.84e-01 -5.78e-02 6.91e-01
Activation of the pre-replicative complex 32 3.84e-01 8.89e-02 6.91e-01
Interleukin-3, Interleukin-5 and GM-CSF signaling 40 3.84e-01 -7.95e-02 6.91e-01
Transport of Mature mRNA derived from an Intron-Containing Transcript 72 3.86e-01 -5.92e-02 6.93e-01
Regulation of commissural axon pathfinding by SLIT and ROBO 10 3.87e-01 1.58e-01 6.93e-01
Apoptosis 152 3.88e-01 4.06e-02 6.94e-01
Negative regulation of FGFR2 signaling 28 3.88e-01 9.42e-02 6.94e-01
Protein ubiquitination 59 3.89e-01 -6.49e-02 6.94e-01
Homology Directed Repair 92 3.90e-01 -5.19e-02 6.94e-01
Aberrant regulation of mitotic exit in cancer due to RB1 defects 18 3.90e-01 -1.17e-01 6.94e-01
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 11 3.90e-01 1.50e-01 6.94e-01
Asymmetric localization of PCP proteins 53 3.91e-01 -6.82e-02 6.94e-01
HDMs demethylate histones 20 3.91e-01 1.11e-01 6.94e-01
eNOS activation 10 3.91e-01 1.57e-01 6.94e-01
ABC transporter disorders 69 3.93e-01 -5.95e-02 6.95e-01
Glycogen synthesis 13 3.93e-01 -1.37e-01 6.96e-01
Passive transport by Aquaporins 10 3.94e-01 1.56e-01 6.96e-01
SHC-mediated cascade:FGFR2 20 3.96e-01 1.10e-01 6.98e-01
Translation of structural proteins 24 3.96e-01 1.00e-01 6.98e-01
Trafficking of GluR2-containing AMPA receptors 17 3.98e-01 -1.19e-01 6.98e-01
Oxidative Stress Induced Senescence 59 3.98e-01 -6.37e-02 6.98e-01
Caspase activation via Dependence Receptors in the absence of ligand 10 3.98e-01 -1.54e-01 6.98e-01
Negative regulation of FGFR4 signaling 25 3.99e-01 9.74e-02 6.98e-01
Formation of HIV-1 elongation complex containing HIV-1 Tat 39 4.00e-01 -7.79e-02 6.98e-01
HIV Transcription Elongation 39 4.00e-01 -7.79e-02 6.98e-01
Tat-mediated elongation of the HIV-1 transcript 39 4.00e-01 -7.79e-02 6.98e-01
Clathrin-mediated endocytosis 132 4.01e-01 4.24e-02 7.00e-01
G beta:gamma signalling through BTK 14 4.03e-01 1.29e-01 7.02e-01
SHC-mediated cascade:FGFR4 17 4.03e-01 1.17e-01 7.02e-01
Activation of RAC1 13 4.06e-01 -1.33e-01 7.06e-01
Acyl chain remodelling of PC 24 4.09e-01 9.73e-02 7.10e-01
activated TAK1 mediates p38 MAPK activation 17 4.10e-01 1.15e-01 7.11e-01
Processive synthesis on the lagging strand 14 4.11e-01 1.27e-01 7.12e-01
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 13 4.14e-01 -1.31e-01 7.15e-01
Deubiquitination 217 4.14e-01 -3.22e-02 7.15e-01
Formation of HIV elongation complex in the absence of HIV Tat 41 4.15e-01 -7.37e-02 7.15e-01
Regulation of PTEN gene transcription 54 4.15e-01 6.41e-02 7.16e-01
Reproduction 77 4.18e-01 -5.34e-02 7.17e-01
Activation of BH3-only proteins 26 4.18e-01 9.17e-02 7.17e-01
Recruitment of NuMA to mitotic centrosomes 73 4.19e-01 5.47e-02 7.17e-01
Signaling by ERBB2 TMD/JMD mutants 18 4.20e-01 1.10e-01 7.17e-01
Downstream signaling of activated FGFR2 27 4.20e-01 8.97e-02 7.17e-01
Regulation of TLR by endogenous ligand 15 4.20e-01 -1.20e-01 7.17e-01
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects 16 4.20e-01 1.16e-01 7.17e-01
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) 16 4.20e-01 1.16e-01 7.17e-01
Hedgehog ligand biogenesis 56 4.21e-01 -6.21e-02 7.18e-01
Acyl chain remodelling of PI 15 4.24e-01 1.19e-01 7.20e-01
Activation of SMO 16 4.24e-01 -1.15e-01 7.20e-01
Iron uptake and transport 50 4.24e-01 6.53e-02 7.20e-01
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 10 4.25e-01 -1.46e-01 7.20e-01
FOXO-mediated transcription of cell cycle genes 16 4.25e-01 -1.15e-01 7.20e-01
Chondroitin sulfate/dermatan sulfate metabolism 46 4.27e-01 6.77e-02 7.23e-01
Voltage gated Potassium channels 39 4.28e-01 7.34e-02 7.23e-01
NCAM1 interactions 31 4.28e-01 8.22e-02 7.23e-01
Constitutive Signaling by EGFRvIII 13 4.31e-01 1.26e-01 7.25e-01
Signaling by EGFRvIII in Cancer 13 4.31e-01 1.26e-01 7.25e-01
Downstream signaling of activated FGFR4 24 4.33e-01 9.26e-02 7.25e-01
GABA receptor activation 52 4.33e-01 6.29e-02 7.25e-01
Glucagon signaling in metabolic regulation 29 4.33e-01 8.41e-02 7.25e-01
Programmed Cell Death 162 4.33e-01 3.57e-02 7.25e-01
G1/S Transition 122 4.33e-01 -4.11e-02 7.25e-01
CS/DS degradation 12 4.35e-01 1.30e-01 7.27e-01
Signaling by FGFR4 34 4.36e-01 7.72e-02 7.27e-01
TP53 Regulates Transcription of DNA Repair Genes 55 4.36e-01 -6.07e-02 7.27e-01
Telomere C-strand synthesis initiation 13 4.39e-01 -1.24e-01 7.31e-01
Vasopressin regulates renal water homeostasis via Aquaporins 37 4.40e-01 7.34e-02 7.31e-01
Signaling by FGFR2 in disease 38 4.40e-01 7.23e-02 7.32e-01
TRAF6 mediated NF-kB activation 19 4.41e-01 1.02e-01 7.32e-01
Signalling to RAS 18 4.44e-01 -1.04e-01 7.35e-01
CD28 dependent PI3K/Akt signaling 21 4.44e-01 9.65e-02 7.35e-01
Mitotic Prophase 80 4.45e-01 -4.94e-02 7.35e-01
CD28 co-stimulation 32 4.45e-01 -7.80e-02 7.35e-01
Gap junction trafficking 24 4.46e-01 9.00e-02 7.35e-01
Gap junction trafficking and regulation 26 4.47e-01 8.61e-02 7.35e-01
Formation of the Early Elongation Complex 31 4.47e-01 -7.89e-02 7.35e-01
Formation of the HIV-1 Early Elongation Complex 31 4.47e-01 -7.89e-02 7.35e-01
Acyl chain remodelling of PG 16 4.48e-01 1.10e-01 7.35e-01
Cell recruitment (pro-inflammatory response) 23 4.49e-01 -9.12e-02 7.36e-01
Purinergic signaling in leishmaniasis infection 23 4.49e-01 -9.12e-02 7.36e-01
Regulation of IFNA signaling 11 4.51e-01 1.31e-01 7.39e-01
Autophagy 116 4.52e-01 -4.04e-02 7.39e-01
RHO GTPases Activate WASPs and WAVEs 34 4.53e-01 7.43e-02 7.39e-01
ERBB2 Regulates Cell Motility 14 4.54e-01 1.16e-01 7.39e-01
SUMOylation of transcription cofactors 41 4.55e-01 6.75e-02 7.39e-01
RNA Polymerase III Chain Elongation 14 4.56e-01 -1.15e-01 7.39e-01
Integrin cell surface interactions 60 4.56e-01 5.57e-02 7.39e-01
IRAK4 deficiency (TLR2/4) 10 4.56e-01 -1.36e-01 7.39e-01
Signaling by FGFR4 in disease 10 4.56e-01 1.36e-01 7.39e-01
EPH-Ephrin signaling 88 4.57e-01 4.59e-02 7.40e-01
Activated NTRK2 signals through FRS2 and FRS3 10 4.58e-01 -1.36e-01 7.40e-01
Metabolism of nitric oxide: NOS3 activation and regulation 14 4.60e-01 1.14e-01 7.43e-01
Aggrephagy 18 4.62e-01 -1.00e-01 7.46e-01
Transport of Mature Transcript to Cytoplasm 80 4.63e-01 -4.75e-02 7.46e-01
Norepinephrine Neurotransmitter Release Cycle 17 4.65e-01 1.02e-01 7.49e-01
Signaling by WNT 243 4.67e-01 2.71e-02 7.50e-01
Mitotic G1 phase and G1/S transition 137 4.68e-01 -3.60e-02 7.50e-01
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 12 4.69e-01 1.21e-01 7.50e-01
Membrane Trafficking 561 4.70e-01 -1.79e-02 7.50e-01
Regulation of RUNX1 Expression and Activity 18 4.71e-01 -9.82e-02 7.50e-01
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein 71 4.71e-01 -4.95e-02 7.50e-01
Gap-filling DNA repair synthesis and ligation in TC-NER 59 4.71e-01 -5.43e-02 7.50e-01
G beta:gamma signalling through CDC42 16 4.72e-01 1.04e-01 7.50e-01
Blood group systems biosynthesis 17 4.72e-01 1.01e-01 7.50e-01
Nucleotide-like (purinergic) receptors 13 4.73e-01 1.15e-01 7.50e-01
Activated NOTCH1 Transmits Signal to the Nucleus 29 4.73e-01 7.70e-02 7.50e-01
Peptide ligand-binding receptors 150 4.74e-01 3.39e-02 7.50e-01
NOTCH3 Intracellular Domain Regulates Transcription 21 4.75e-01 9.01e-02 7.50e-01
Centrosome maturation 74 4.75e-01 4.81e-02 7.50e-01
Recruitment of mitotic centrosome proteins and complexes 74 4.75e-01 4.81e-02 7.50e-01
Loss of Nlp from mitotic centrosomes 65 4.75e-01 5.12e-02 7.50e-01
Loss of proteins required for interphase microtubule organization from the centrosome 65 4.75e-01 5.12e-02 7.50e-01
Interactions of Rev with host cellular proteins 35 4.77e-01 6.94e-02 7.52e-01
Interferon alpha/beta signaling 49 4.79e-01 5.85e-02 7.52e-01
MyD88 cascade initiated on plasma membrane 73 4.79e-01 4.79e-02 7.52e-01
Toll Like Receptor 10 (TLR10) Cascade 73 4.79e-01 4.79e-02 7.52e-01
Toll Like Receptor 5 (TLR5) Cascade 73 4.79e-01 4.79e-02 7.52e-01
DCC mediated attractive signaling 14 4.80e-01 1.09e-01 7.52e-01
MECP2 regulates neuronal receptors and channels 16 4.80e-01 1.02e-01 7.52e-01
Semaphorin interactions 61 4.80e-01 5.23e-02 7.52e-01
MET activates RAS signaling 10 4.82e-01 -1.28e-01 7.53e-01
Deadenylation of mRNA 20 4.82e-01 9.07e-02 7.53e-01
AURKA Activation by TPX2 68 4.85e-01 4.90e-02 7.57e-01
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 19 4.86e-01 9.24e-02 7.57e-01
HSP90 chaperone cycle for steroid hormone receptors (SHR) 34 4.87e-01 -6.89e-02 7.58e-01
Meiotic synapsis 33 4.89e-01 -6.96e-02 7.60e-01
MAP2K and MAPK activation 36 4.91e-01 -6.64e-02 7.62e-01
Synthesis of very long-chain fatty acyl-CoAs 24 4.92e-01 8.10e-02 7.64e-01
Role of LAT2/NTAL/LAB on calcium mobilization 25 4.94e-01 -7.90e-02 7.65e-01
Complement cascade 57 4.95e-01 -5.23e-02 7.66e-01
Phase 4 - resting membrane potential 16 4.95e-01 -9.85e-02 7.66e-01
Apoptosis induced DNA fragmentation 11 4.98e-01 1.18e-01 7.69e-01
Positive epigenetic regulation of rRNA expression 45 5.00e-01 -5.81e-02 7.70e-01
CREB1 phosphorylation through the activation of Adenylate Cyclase 11 5.00e-01 -1.17e-01 7.70e-01
Resolution of Abasic Sites (AP sites) 37 5.03e-01 6.37e-02 7.72e-01
NF-kB is activated and signals survival 10 5.03e-01 1.22e-01 7.72e-01
tRNA processing in the nucleus 53 5.03e-01 -5.32e-02 7.72e-01
Vitamin D (calciferol) metabolism 10 5.04e-01 -1.22e-01 7.72e-01
Cyclin D associated events in G1 41 5.05e-01 -6.03e-02 7.72e-01
G1 Phase 41 5.05e-01 -6.03e-02 7.72e-01
PIWI-interacting RNA (piRNA) biogenesis 26 5.05e-01 -7.56e-02 7.72e-01
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 16 5.06e-01 -9.61e-02 7.73e-01
Nuclear Pore Complex (NPC) Disassembly 34 5.07e-01 -6.57e-02 7.74e-01
Creatine metabolism 10 5.09e-01 -1.21e-01 7.76e-01
Serotonin Neurotransmitter Release Cycle 17 5.11e-01 9.21e-02 7.78e-01
Signaling by ERBB4 52 5.12e-01 -5.25e-02 7.78e-01
Keratan sulfate biosynthesis 25 5.13e-01 -7.57e-02 7.78e-01
HDR through Homologous Recombination (HRR) 60 5.13e-01 -4.88e-02 7.78e-01
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 12 5.13e-01 -1.09e-01 7.78e-01
PPARA activates gene expression 113 5.14e-01 3.56e-02 7.79e-01
Signaling by Receptor Tyrosine Kinases 449 5.15e-01 1.80e-02 7.79e-01
Dual Incision in GG-NER 37 5.16e-01 -6.17e-02 7.80e-01
RNA Polymerase I Transcription Initiation 44 5.17e-01 -5.65e-02 7.80e-01
Class A/1 (Rhodopsin-like receptors) 255 5.17e-01 2.36e-02 7.80e-01
Amine ligand-binding receptors 35 5.18e-01 6.32e-02 7.80e-01
Interferon Signaling 159 5.19e-01 -2.97e-02 7.80e-01
Striated Muscle Contraction 31 5.19e-01 -6.69e-02 7.80e-01
Diseases of signal transduction by growth factor receptors and second messengers 347 5.19e-01 2.02e-02 7.80e-01
Role of phospholipids in phagocytosis 36 5.20e-01 -6.20e-02 7.80e-01
Metabolism of nucleotides 89 5.21e-01 3.94e-02 7.81e-01
Post-translational modification: synthesis of GPI-anchored proteins 75 5.22e-01 4.27e-02 7.81e-01
Glycogen storage diseases 12 5.23e-01 1.07e-01 7.81e-01
Glycosaminoglycan metabolism 108 5.23e-01 3.56e-02 7.81e-01
Signaling by BMP 25 5.24e-01 7.36e-02 7.82e-01
mRNA 3’-end processing 54 5.25e-01 -5.00e-02 7.82e-01
RNA Polymerase III Transcription Initiation From Type 3 Promoter 24 5.25e-01 -7.49e-02 7.82e-01
Transmission across Chemical Synapses 221 5.27e-01 2.47e-02 7.84e-01
Vitamin B5 (pantothenate) metabolism 14 5.28e-01 9.74e-02 7.85e-01
Interleukin-15 signaling 13 5.31e-01 1.00e-01 7.88e-01
EPHB-mediated forward signaling 33 5.32e-01 -6.28e-02 7.89e-01
Regulation of innate immune responses to cytosolic DNA 12 5.35e-01 -1.03e-01 7.91e-01
Signaling by NOTCH 169 5.36e-01 -2.76e-02 7.91e-01
Platelet activation, signaling and aggregation 240 5.36e-01 2.32e-02 7.91e-01
Stimuli-sensing channels 94 5.37e-01 -3.69e-02 7.91e-01
Disorders of transmembrane transporters 161 5.37e-01 2.82e-02 7.91e-01
Formation of the cornified envelope 33 5.37e-01 6.21e-02 7.91e-01
Effects of PIP2 hydrolysis 26 5.38e-01 6.97e-02 7.92e-01
Association of TriC/CCT with target proteins during biosynthesis 38 5.39e-01 5.76e-02 7.92e-01
Elastic fibre formation 37 5.41e-01 -5.81e-02 7.92e-01
Class C/3 (Metabotropic glutamate/pheromone receptors) 29 5.41e-01 6.56e-02 7.92e-01
ZBP1(DAI) mediated induction of type I IFNs 19 5.41e-01 8.10e-02 7.92e-01
Activation of Ca-permeable Kainate Receptor 10 5.41e-01 -1.12e-01 7.92e-01
Ionotropic activity of kainate receptors 10 5.41e-01 -1.12e-01 7.92e-01
Fatty acyl-CoA biosynthesis 35 5.42e-01 5.95e-02 7.92e-01
Glutamate and glutamine metabolism 12 5.46e-01 1.01e-01 7.96e-01
p75NTR recruits signalling complexes 11 5.47e-01 -1.05e-01 7.98e-01
Elevation of cytosolic Ca2+ levels 15 5.48e-01 8.96e-02 7.98e-01
Rho GTPase cycle 129 5.49e-01 3.06e-02 7.99e-01
Factors involved in megakaryocyte development and platelet production 110 5.49e-01 3.31e-02 7.99e-01
Telomere Extension By Telomerase 22 5.51e-01 7.35e-02 8.00e-01
Interleukin-6 signaling 10 5.56e-01 1.08e-01 8.06e-01
COPI-dependent Golgi-to-ER retrograde traffic 77 5.57e-01 -3.87e-02 8.07e-01
Carnitine metabolism 11 5.58e-01 1.02e-01 8.07e-01
Killing mechanisms 12 5.59e-01 9.74e-02 8.07e-01
WNT5:FZD7-mediated leishmania damping 12 5.59e-01 9.74e-02 8.07e-01
Processing of Capped Intronless Pre-mRNA 24 5.59e-01 -6.89e-02 8.07e-01
CLEC7A (Dectin-1) induces NFAT activation 11 5.60e-01 1.01e-01 8.07e-01
Nicotinate metabolism 30 5.61e-01 6.14e-02 8.07e-01
Ion transport by P-type ATPases 49 5.66e-01 4.75e-02 8.09e-01
EPH-ephrin mediated repulsion of cells 47 5.66e-01 4.84e-02 8.09e-01
Pausing and recovery of Tat-mediated HIV elongation 27 5.66e-01 -6.39e-02 8.09e-01
Tat-mediated HIV elongation arrest and recovery 27 5.66e-01 -6.39e-02 8.09e-01
Regulation of TP53 Activity through Acetylation 28 5.67e-01 6.25e-02 8.09e-01
Activation of G protein gated Potassium channels 22 5.67e-01 7.05e-02 8.09e-01
G protein gated Potassium channels 22 5.67e-01 7.05e-02 8.09e-01
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 22 5.67e-01 7.05e-02 8.09e-01
Activation of kainate receptors upon glutamate binding 26 5.69e-01 6.46e-02 8.09e-01
Integrin signaling 27 5.69e-01 -6.33e-02 8.09e-01
Regulation of gene expression by Hypoxia-inducible Factor 11 5.69e-01 9.91e-02 8.09e-01
Nervous system development 491 5.71e-01 -1.50e-02 8.09e-01
Downregulation of SMAD2/3:SMAD4 transcriptional activity 21 5.71e-01 -7.15e-02 8.09e-01
Signaling by NOTCH2 28 5.72e-01 6.18e-02 8.09e-01
Anti-inflammatory response favouring Leishmania parasite infection 151 5.72e-01 -2.66e-02 8.09e-01
Leishmania parasite growth and survival 151 5.72e-01 -2.66e-02 8.09e-01
Lewis blood group biosynthesis 13 5.73e-01 9.04e-02 8.09e-01
Toll Like Receptor 9 (TLR9) Cascade 81 5.73e-01 3.63e-02 8.09e-01
Gastrin-CREB signalling pathway via PKC and MAPK 15 5.73e-01 -8.41e-02 8.09e-01
TAK1 activates NFkB by phosphorylation and activation of IKKs complex 23 5.73e-01 6.79e-02 8.09e-01
Regulation of PLK1 Activity at G2/M Transition 80 5.79e-01 3.59e-02 8.16e-01
WNT5A-dependent internalization of FZD4 14 5.79e-01 8.56e-02 8.16e-01
Nuclear signaling by ERBB4 29 5.81e-01 5.92e-02 8.17e-01
Removal of the Flap Intermediate 13 5.84e-01 8.77e-02 8.18e-01
HIV elongation arrest and recovery 29 5.84e-01 -5.88e-02 8.18e-01
Pausing and recovery of HIV elongation 29 5.84e-01 -5.88e-02 8.18e-01
Misspliced GSK3beta mutants stabilize beta-catenin 13 5.86e-01 8.72e-02 8.18e-01
S33 mutants of beta-catenin aren’t phosphorylated 13 5.86e-01 8.72e-02 8.18e-01
S37 mutants of beta-catenin aren’t phosphorylated 13 5.86e-01 8.72e-02 8.18e-01
S45 mutants of beta-catenin aren’t phosphorylated 13 5.86e-01 8.72e-02 8.18e-01
T41 mutants of beta-catenin aren’t phosphorylated 13 5.86e-01 8.72e-02 8.18e-01
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 13 5.86e-01 8.72e-02 8.18e-01
FGFR2 mutant receptor activation 29 5.88e-01 5.81e-02 8.18e-01
Negative epigenetic regulation of rRNA expression 51 5.88e-01 4.38e-02 8.18e-01
Phase 2 - plateau phase 12 5.88e-01 9.03e-02 8.18e-01
Base-Excision Repair, AP Site Formation 20 5.89e-01 6.97e-02 8.18e-01
MyD88 dependent cascade initiated on endosome 77 5.91e-01 3.54e-02 8.20e-01
Transcriptional regulation of pluripotent stem cells 27 5.92e-01 -5.97e-02 8.20e-01
Metabolism of folate and pterines 17 5.92e-01 -7.51e-02 8.20e-01
Diseases of glycosylation 126 5.93e-01 -2.76e-02 8.20e-01
Inflammasomes 19 5.96e-01 -7.02e-02 8.24e-01
Prostacyclin signalling through prostacyclin receptor 15 5.97e-01 7.89e-02 8.24e-01
Rev-mediated nuclear export of HIV RNA 33 5.97e-01 5.32e-02 8.24e-01
NR1H2 and NR1H3-mediated signaling 48 5.98e-01 4.40e-02 8.24e-01
Abortive elongation of HIV-1 transcript in the absence of Tat 21 6.00e-01 -6.62e-02 8.25e-01
Cholesterol biosynthesis 21 6.00e-01 6.61e-02 8.25e-01
Inhibition of replication initiation of damaged DNA by RB1/E2F1 12 6.02e-01 -8.70e-02 8.26e-01
Telomere C-strand (Lagging Strand) Synthesis 33 6.02e-01 -5.24e-02 8.26e-01
Adenylate cyclase activating pathway 10 6.04e-01 9.47e-02 8.28e-01
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 97 6.05e-01 3.04e-02 8.28e-01
O-linked glycosylation 90 6.06e-01 -3.15e-02 8.29e-01
TP53 Regulates Transcription of Cell Death Genes 34 6.06e-01 -5.11e-02 8.29e-01
Activation of gene expression by SREBF (SREBP) 40 6.07e-01 4.70e-02 8.29e-01
RAF activation 31 6.11e-01 -5.28e-02 8.33e-01
Signaling by FGFR2 IIIa TM 17 6.11e-01 -7.12e-02 8.33e-01
HSF1 activation 24 6.13e-01 5.97e-02 8.34e-01
Regulation of PTEN mRNA translation 19 6.14e-01 -6.69e-02 8.35e-01
MyD88:MAL(TIRAP) cascade initiated on plasma membrane 83 6.17e-01 3.17e-02 8.35e-01
Toll Like Receptor 2 (TLR2) Cascade 83 6.17e-01 3.17e-02 8.35e-01
Toll Like Receptor TLR1:TLR2 Cascade 83 6.17e-01 3.17e-02 8.35e-01
Toll Like Receptor TLR6:TLR2 Cascade 83 6.17e-01 3.17e-02 8.35e-01
Signaling by PDGFRA extracellular domain mutants 10 6.18e-01 9.12e-02 8.35e-01
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants 10 6.18e-01 9.12e-02 8.35e-01
HDR through Single Strand Annealing (SSA) 35 6.19e-01 -4.86e-02 8.36e-01
Repression of WNT target genes 14 6.21e-01 7.63e-02 8.38e-01
Chemokine receptors bind chemokines 41 6.21e-01 4.46e-02 8.38e-01
Termination of translesion DNA synthesis 27 6.22e-01 5.48e-02 8.39e-01
FRS-mediated FGFR1 signaling 20 6.24e-01 6.34e-02 8.40e-01
NoRC negatively regulates rRNA expression 48 6.25e-01 4.08e-02 8.40e-01
Epigenetic regulation of gene expression 87 6.29e-01 3.00e-02 8.43e-01
Peptide hormone metabolism 81 6.29e-01 -3.11e-02 8.43e-01
DDX58/IFIH1-mediated induction of interferon-alpha/beta 53 6.29e-01 3.83e-02 8.43e-01
G alpha (s) signalling events 195 6.32e-01 -1.99e-02 8.43e-01
Infection with Mycobacterium tuberculosis 24 6.32e-01 -5.65e-02 8.43e-01
Acyl chain remodelling of PE 25 6.32e-01 5.53e-02 8.43e-01
NRIF signals cell death from the nucleus 14 6.32e-01 -7.39e-02 8.43e-01
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function 39 6.33e-01 -4.42e-02 8.43e-01
Interleukin-20 family signaling 16 6.34e-01 -6.88e-02 8.43e-01
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 76 6.34e-01 3.16e-02 8.43e-01
Transcriptional Regulation by TP53 325 6.34e-01 -1.54e-02 8.43e-01
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 16 6.36e-01 -6.84e-02 8.45e-01
MET activates RAP1 and RAC1 11 6.36e-01 8.23e-02 8.45e-01
Toll Like Receptor 7/8 (TLR7/8) Cascade 78 6.38e-01 3.09e-02 8.46e-01
Syndecan interactions 19 6.38e-01 6.23e-02 8.46e-01
Regulation of signaling by CBL 17 6.40e-01 -6.55e-02 8.48e-01
Signaling by EGFR in Cancer 21 6.44e-01 5.83e-02 8.52e-01
BBSome-mediated cargo-targeting to cilium 21 6.46e-01 -5.79e-02 8.54e-01
Class B/2 (Secretin family receptors) 78 6.48e-01 3.00e-02 8.55e-01
NOTCH2 Activation and Transmission of Signal to the Nucleus 19 6.49e-01 6.04e-02 8.56e-01
The role of Nef in HIV-1 replication and disease pathogenesis 26 6.51e-01 5.13e-02 8.57e-01
Listeria monocytogenes entry into host cells 18 6.51e-01 6.15e-02 8.57e-01
DNA strand elongation 31 6.52e-01 4.68e-02 8.57e-01
Regulation of Complement cascade 49 6.52e-01 -3.73e-02 8.57e-01
Resolution of D-loop Structures through Holliday Junction Intermediates 30 6.52e-01 4.76e-02 8.57e-01
Organic cation/anion/zwitterion transport 12 6.53e-01 7.49e-02 8.57e-01
Signaling by Hippo 20 6.54e-01 5.79e-02 8.57e-01
Inwardly rectifying K+ channels 28 6.55e-01 4.88e-02 8.57e-01
G2/M Transition 165 6.56e-01 -2.01e-02 8.57e-01
Synthesis of PC 28 6.56e-01 4.87e-02 8.57e-01
Transport of the SLBP Dependant Mature mRNA 35 6.57e-01 -4.34e-02 8.58e-01
Mitotic G2-G2/M phases 167 6.58e-01 -1.99e-02 8.58e-01
TP53 Regulates Transcription of Cell Cycle Genes 47 6.62e-01 3.68e-02 8.63e-01
ERK/MAPK targets 20 6.64e-01 5.61e-02 8.65e-01
Unfolded Protein Response (UPR) 89 6.65e-01 2.66e-02 8.65e-01
Interleukin-2 family signaling 38 6.65e-01 -4.06e-02 8.65e-01
MET promotes cell motility 28 6.68e-01 4.69e-02 8.67e-01
Ca2+ pathway 54 6.71e-01 3.35e-02 8.70e-01
Amyloid fiber formation 48 6.72e-01 3.54e-02 8.71e-01
Diseases associated with glycosylation precursor biosynthesis 17 6.74e-01 5.89e-02 8.73e-01
Interleukin-6 family signaling 23 6.75e-01 5.05e-02 8.73e-01
Physiological factors 12 6.76e-01 6.98e-02 8.73e-01
Glutathione synthesis and recycling 11 6.76e-01 7.27e-02 8.73e-01
Antiviral mechanism by IFN-stimulated genes 74 6.78e-01 -2.80e-02 8.74e-01
Interleukin-35 Signalling 11 6.78e-01 7.23e-02 8.74e-01
Beta-catenin phosphorylation cascade 15 6.79e-01 6.18e-02 8.74e-01
FRS-mediated FGFR2 signaling 22 6.79e-01 5.10e-02 8.74e-01
Termination of O-glycan biosynthesis 14 6.80e-01 6.37e-02 8.74e-01
MicroRNA (miRNA) biogenesis 22 6.85e-01 -5.00e-02 8.80e-01
PCP/CE pathway 80 6.85e-01 -2.62e-02 8.80e-01
Recognition of DNA damage by PCNA-containing replication complex 27 6.87e-01 -4.48e-02 8.80e-01
Signaling by BRAF and RAF fusions 59 6.88e-01 3.02e-02 8.80e-01
Gap-filling DNA repair synthesis and ligation in GG-NER 22 6.88e-01 -4.95e-02 8.80e-01
Downregulation of ERBB2:ERBB3 signaling 11 6.88e-01 6.98e-02 8.80e-01
Erythropoietin activates RAS 13 6.91e-01 6.37e-02 8.81e-01
Response to elevated platelet cytosolic Ca2+ 125 6.91e-01 2.06e-02 8.81e-01
Interleukin-1 signaling 89 6.92e-01 -2.43e-02 8.81e-01
Detoxification of Reactive Oxygen Species 32 6.92e-01 4.05e-02 8.81e-01
Cobalamin (Cbl, vitamin B12) transport and metabolism 17 6.92e-01 -5.54e-02 8.81e-01
Signaling by NOTCH1 67 6.93e-01 -2.79e-02 8.82e-01
Insulin processing 25 6.94e-01 -4.55e-02 8.82e-01
NS1 Mediated Effects on Host Pathways 39 6.95e-01 -3.63e-02 8.82e-01
ERBB2 Activates PTK6 Signaling 12 6.95e-01 6.53e-02 8.82e-01
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 31 6.97e-01 4.04e-02 8.83e-01
Regulation of Glucokinase by Glucokinase Regulatory Protein 31 6.97e-01 4.04e-02 8.83e-01
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 28 6.99e-01 -4.22e-02 8.84e-01
Signaling by NTRK3 (TRKC) 16 7.01e-01 5.55e-02 8.86e-01
Lagging Strand Synthesis 19 7.02e-01 -5.07e-02 8.86e-01
Platelet Adhesion to exposed collagen 12 7.04e-01 6.35e-02 8.87e-01
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 15 7.04e-01 5.66e-02 8.87e-01
Signaling by Ligand-Responsive EGFR Variants in Cancer 15 7.04e-01 5.66e-02 8.87e-01
DSCAM interactions 11 7.06e-01 -6.57e-02 8.88e-01
Estrogen-dependent nuclear events downstream of ESR-membrane signaling 21 7.06e-01 4.75e-02 8.88e-01
Digestion and absorption 20 7.07e-01 -4.85e-02 8.88e-01
Regulation of cholesterol biosynthesis by SREBP (SREBF) 51 7.07e-01 -3.04e-02 8.88e-01
Interleukin-27 signaling 11 7.08e-01 6.52e-02 8.88e-01
Oncogene Induced Senescence 28 7.09e-01 -4.07e-02 8.88e-01
Synthesis of substrates in N-glycan biosythesis 57 7.10e-01 -2.85e-02 8.89e-01
Signaling by MET 62 7.12e-01 -2.72e-02 8.90e-01
Plasma lipoprotein assembly 18 7.14e-01 -4.99e-02 8.91e-01
Transcriptional Regulation by VENTX 35 7.15e-01 -3.57e-02 8.91e-01
FRS-mediated FGFR4 signaling 19 7.15e-01 4.84e-02 8.91e-01
Signaling by Rho GTPases 356 7.15e-01 1.13e-02 8.91e-01
GRB2 events in ERBB2 signaling 14 7.17e-01 5.61e-02 8.92e-01
Vpr-mediated nuclear import of PICs 32 7.19e-01 -3.67e-02 8.93e-01
Protein methylation 14 7.20e-01 -5.53e-02 8.93e-01
RNA Polymerase III Abortive And Retractive Initiation 37 7.20e-01 -3.40e-02 8.93e-01
RNA Polymerase III Transcription 37 7.20e-01 -3.40e-02 8.93e-01
Presynaptic phase of homologous DNA pairing and strand exchange 36 7.20e-01 -3.45e-02 8.93e-01
MAPK family signaling cascades 292 7.21e-01 -1.22e-02 8.93e-01
HCMV Early Events 59 7.22e-01 -2.67e-02 8.94e-01
RNA Polymerase I Transcription Termination 28 7.23e-01 -3.87e-02 8.94e-01
DNA Damage/Telomere Stress Induced Senescence 33 7.24e-01 -3.55e-02 8.94e-01
Gap junction assembly 16 7.25e-01 5.08e-02 8.94e-01
Free fatty acids regulate insulin secretion 10 7.26e-01 6.39e-02 8.95e-01
Formation of Incision Complex in GG-NER 39 7.27e-01 -3.23e-02 8.95e-01
Myogenesis 29 7.27e-01 -3.74e-02 8.95e-01
Diseases associated with the TLR signaling cascade 20 7.29e-01 -4.48e-02 8.95e-01
Diseases of Immune System 20 7.29e-01 -4.48e-02 8.95e-01
Resolution of AP sites via the multiple-nucleotide patch replacement pathway 24 7.35e-01 -3.99e-02 9.01e-01
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 12 7.36e-01 5.62e-02 9.01e-01
MyD88-independent TLR4 cascade 83 7.36e-01 -2.14e-02 9.01e-01
TRIF(TICAM1)-mediated TLR4 signaling 83 7.36e-01 -2.14e-02 9.01e-01
Signaling by FGFR 72 7.38e-01 2.28e-02 9.02e-01
Basigin interactions 25 7.40e-01 3.84e-02 9.04e-01
Nuclear import of Rev protein 32 7.40e-01 3.39e-02 9.04e-01
Activation of the TFAP2 (AP-2) family of transcription factors 11 7.43e-01 5.72e-02 9.06e-01
PLC beta mediated events 50 7.43e-01 2.68e-02 9.06e-01
MAP kinase activation 57 7.45e-01 2.49e-02 9.06e-01
DNA Damage Bypass 41 7.45e-01 2.93e-02 9.06e-01
DAG and IP3 signaling 38 7.45e-01 -3.05e-02 9.06e-01
Digestion 15 7.47e-01 -4.81e-02 9.07e-01
Intra-Golgi traffic 40 7.48e-01 -2.94e-02 9.07e-01
Interleukin-7 signaling 21 7.49e-01 -4.03e-02 9.07e-01
Signaling by high-kinase activity BRAF mutants 32 7.49e-01 -3.26e-02 9.07e-01
MAP3K8 (TPL2)-dependent MAPK1/3 activation 14 7.49e-01 -4.93e-02 9.07e-01
Sealing of the nuclear envelope (NE) by ESCRT-III 23 7.54e-01 3.77e-02 9.12e-01
Degradation of cysteine and homocysteine 10 7.56e-01 5.69e-02 9.13e-01
Chromatin modifying enzymes 195 7.58e-01 -1.28e-02 9.14e-01
Chromatin organization 195 7.58e-01 -1.28e-02 9.14e-01
Cargo recognition for clathrin-mediated endocytosis 96 7.59e-01 -1.81e-02 9.15e-01
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) 12 7.61e-01 -5.07e-02 9.16e-01
SHC1 events in EGFR signaling 13 7.61e-01 -4.87e-02 9.16e-01
Regulation of actin dynamics for phagocytic cup formation 70 7.65e-01 2.07e-02 9.19e-01
Retrograde transport at the Trans-Golgi-Network 44 7.66e-01 -2.60e-02 9.19e-01
Amino acid transport across the plasma membrane 31 7.66e-01 3.09e-02 9.19e-01
Signaling by FGFR2 61 7.68e-01 -2.19e-02 9.20e-01
Sodium/Calcium exchangers 11 7.69e-01 5.12e-02 9.21e-01
TRAF3-dependent IRF activation pathway 12 7.70e-01 4.87e-02 9.21e-01
Tie2 Signaling 16 7.70e-01 -4.21e-02 9.21e-01
Diseases associated with glycosaminoglycan metabolism 38 7.70e-01 2.74e-02 9.21e-01
G2/M DNA damage checkpoint 56 7.72e-01 -2.24e-02 9.21e-01
Nucleotide salvage 21 7.72e-01 3.66e-02 9.21e-01
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 31 7.73e-01 -2.99e-02 9.22e-01
PRC2 methylates histones and DNA 17 7.74e-01 4.01e-02 9.22e-01
SUMOylation of intracellular receptors 29 7.76e-01 -3.06e-02 9.23e-01
Pregnenolone biosynthesis 11 7.77e-01 4.92e-02 9.24e-01
Signaling by TGFB family members 91 7.78e-01 1.71e-02 9.24e-01
Platelet Aggregation (Plug Formation) 36 7.78e-01 -2.71e-02 9.24e-01
FOXO-mediated transcription 63 7.82e-01 2.02e-02 9.27e-01
Cytochrome c-mediated apoptotic response 10 7.83e-01 5.03e-02 9.28e-01
Signaling by PDGF 48 7.87e-01 -2.26e-02 9.31e-01
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 32 7.89e-01 2.74e-02 9.32e-01
ATF4 activates genes in response to endoplasmic reticulum stress 25 7.89e-01 -3.09e-02 9.32e-01
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 24 7.90e-01 3.14e-02 9.33e-01
EPHA-mediated growth cone collapse 14 7.92e-01 -4.07e-02 9.33e-01
Regulation of TNFR1 signaling 30 7.93e-01 -2.77e-02 9.33e-01
Response of Mtb to phagocytosis 20 7.94e-01 -3.37e-02 9.33e-01
PTEN Regulation 134 7.94e-01 -1.31e-02 9.33e-01
Signaling by EGFR 47 7.94e-01 2.20e-02 9.33e-01
Interleukin-17 signaling 64 7.94e-01 1.88e-02 9.33e-01
TNFR1-induced NFkappaB signaling pathway 23 7.95e-01 3.14e-02 9.33e-01
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion 14 7.97e-01 3.96e-02 9.35e-01
ECM proteoglycans 52 7.98e-01 2.05e-02 9.35e-01
ABC-family proteins mediated transport 92 7.99e-01 -1.53e-02 9.35e-01
Fertilization 19 8.00e-01 3.36e-02 9.35e-01
Signaling by NTRK1 (TRKA) 107 8.01e-01 1.41e-02 9.35e-01
Viral Messenger RNA Synthesis 41 8.02e-01 -2.27e-02 9.35e-01
Surfactant metabolism 24 8.02e-01 2.96e-02 9.35e-01
Ion channel transport 161 8.03e-01 1.14e-02 9.35e-01
Signalling to ERKs 30 8.03e-01 2.63e-02 9.35e-01
Transport of bile salts and organic acids, metal ions and amine compounds 77 8.04e-01 1.64e-02 9.35e-01
Beta-catenin independent WNT signaling 127 8.04e-01 -1.28e-02 9.35e-01
Metal ion SLC transporters 24 8.05e-01 -2.92e-02 9.35e-01
Depolymerisation of the Nuclear Lamina 15 8.05e-01 3.68e-02 9.35e-01
Tandem pore domain potassium channels 10 8.12e-01 4.34e-02 9.42e-01
RAF-independent MAPK1/3 activation 21 8.13e-01 2.98e-02 9.42e-01
SUMOylation of SUMOylation proteins 33 8.14e-01 -2.37e-02 9.42e-01
Metabolic disorders of biological oxidation enzymes 32 8.15e-01 2.39e-02 9.43e-01
Chondroitin sulfate biosynthesis 20 8.18e-01 -2.97e-02 9.46e-01
RAF/MAP kinase cascade 250 8.19e-01 8.42e-03 9.46e-01
mRNA Capping 27 8.20e-01 -2.54e-02 9.46e-01
G-protein beta:gamma signalling 28 8.26e-01 2.40e-02 9.48e-01
AMER1 mutants destabilize the destruction complex 12 8.26e-01 3.66e-02 9.48e-01
APC truncation mutants have impaired AXIN binding 12 8.26e-01 3.66e-02 9.48e-01
AXIN missense mutants destabilize the destruction complex 12 8.26e-01 3.66e-02 9.48e-01
AXIN mutants destabilize the destruction complex, activating WNT signaling 12 8.26e-01 3.66e-02 9.48e-01
Truncations of AMER1 destabilize the destruction complex 12 8.26e-01 3.66e-02 9.48e-01
truncated APC mutants destabilize the destruction complex 12 8.26e-01 3.66e-02 9.48e-01
Antigen Presentation: Folding, assembly and peptide loading of class I MHC 22 8.27e-01 2.69e-02 9.48e-01
CDC6 association with the ORC:origin complex 11 8.28e-01 -3.79e-02 9.48e-01
Netrin-1 signaling 47 8.29e-01 1.82e-02 9.48e-01
PI3K/AKT Signaling in Cancer 95 8.31e-01 1.27e-02 9.48e-01
Neurotransmitter receptors and postsynaptic signal transmission 160 8.31e-01 9.80e-03 9.48e-01
Base Excision Repair 47 8.31e-01 1.80e-02 9.48e-01
Keratinization 84 8.31e-01 -1.34e-02 9.48e-01
RUNX3 regulates NOTCH signaling 12 8.31e-01 -3.55e-02 9.48e-01
Transport of the SLBP independent Mature mRNA 34 8.32e-01 -2.11e-02 9.48e-01
Ephrin signaling 18 8.34e-01 2.86e-02 9.49e-01
SUMO E3 ligases SUMOylate target proteins 155 8.36e-01 9.66e-03 9.49e-01
Cleavage of the damaged pyrimidine 18 8.37e-01 2.80e-02 9.49e-01
Depyrimidination 18 8.37e-01 2.80e-02 9.49e-01
Recognition and association of DNA glycosylase with site containing an affected pyrimidine 18 8.37e-01 2.80e-02 9.49e-01
SUMOylation of immune response proteins 10 8.37e-01 -3.75e-02 9.49e-01
Interleukin-12 family signaling 49 8.38e-01 1.69e-02 9.49e-01
Mitophagy 24 8.39e-01 -2.40e-02 9.49e-01
InlB-mediated entry of Listeria monocytogenes into host cell 13 8.39e-01 -3.25e-02 9.49e-01
Purine salvage 13 8.40e-01 3.24e-02 9.49e-01
SUMOylation of DNA replication proteins 43 8.40e-01 1.77e-02 9.49e-01
Leishmania infection 230 8.42e-01 -7.66e-03 9.49e-01
Chylomicron assembly 10 8.42e-01 -3.64e-02 9.49e-01
SHC1 events in ERBB2 signaling 20 8.43e-01 -2.56e-02 9.49e-01
FCGR3A-mediated phagocytosis 69 8.44e-01 -1.37e-02 9.49e-01
Leishmania phagocytosis 69 8.44e-01 -1.37e-02 9.49e-01
Parasite infection 69 8.44e-01 -1.37e-02 9.49e-01
WNT ligand biogenesis and trafficking 25 8.46e-01 2.25e-02 9.49e-01
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 16 8.46e-01 2.80e-02 9.49e-01
Toll Like Receptor 4 (TLR4) Cascade 110 8.47e-01 -1.07e-02 9.49e-01
Transcription of E2F targets under negative control by DREAM complex 19 8.48e-01 2.54e-02 9.49e-01
Signaling by cytosolic FGFR1 fusion mutants 17 8.48e-01 -2.68e-02 9.49e-01
RAB geranylgeranylation 58 8.49e-01 1.45e-02 9.49e-01
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 37 8.50e-01 1.80e-02 9.49e-01
Phase II - Conjugation of compounds 76 8.51e-01 -1.25e-02 9.49e-01
Competing endogenous RNAs (ceRNAs) regulate PTEN translation 13 8.51e-01 -3.00e-02 9.49e-01
Regulation of signaling by NODAL 11 8.51e-01 -3.26e-02 9.49e-01
Nuclear Envelope Breakdown 50 8.52e-01 -1.52e-02 9.49e-01
Dopamine Neurotransmitter Release Cycle 21 8.54e-01 -2.32e-02 9.49e-01
VxPx cargo-targeting to cilium 20 8.56e-01 2.34e-02 9.49e-01
PIP3 activates AKT signaling 252 8.56e-01 6.64e-03 9.49e-01
Aberrant regulation of mitotic cell cycle due to RB1 defects 33 8.56e-01 -1.82e-02 9.49e-01
Diseases of mitotic cell cycle 33 8.56e-01 -1.82e-02 9.49e-01
Synthesis of IP3 and IP4 in the cytosol 26 8.56e-01 2.05e-02 9.49e-01
GRB2 events in EGFR signaling 12 8.61e-01 -2.91e-02 9.49e-01
Estrogen-dependent gene expression 90 8.61e-01 1.07e-02 9.49e-01
mRNA decay by 5’ to 3’ exoribonuclease 14 8.62e-01 -2.69e-02 9.49e-01
Activation of ATR in response to replication stress 36 8.62e-01 1.67e-02 9.49e-01
Signaling by Erythropoietin 23 8.63e-01 -2.08e-02 9.49e-01
Constitutive Signaling by Aberrant PI3K in Cancer 70 8.64e-01 1.19e-02 9.49e-01
KSRP (KHSRP) binds and destabilizes mRNA 16 8.64e-01 2.48e-02 9.49e-01
Tight junction interactions 24 8.64e-01 2.03e-02 9.49e-01
Macroautophagy 103 8.64e-01 -9.78e-03 9.49e-01
Negative regulators of DDX58/IFIH1 signaling 28 8.64e-01 1.87e-02 9.49e-01
Downstream signal transduction 27 8.66e-01 1.88e-02 9.49e-01
Spry regulation of FGF signaling 12 8.66e-01 2.82e-02 9.49e-01
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 52 8.67e-01 -1.34e-02 9.49e-01
Constitutive Signaling by NOTCH1 PEST Domain Mutants 52 8.67e-01 -1.34e-02 9.49e-01
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 52 8.67e-01 -1.34e-02 9.49e-01
Signaling by NOTCH1 PEST Domain Mutants in Cancer 52 8.67e-01 -1.34e-02 9.49e-01
Signaling by NOTCH1 in Cancer 52 8.67e-01 -1.34e-02 9.49e-01
O-linked glycosylation of mucins 43 8.68e-01 1.47e-02 9.49e-01
NOTCH2 intracellular domain regulates transcription 10 8.68e-01 -3.03e-02 9.49e-01
Negative regulation of TCF-dependent signaling by WNT ligand antagonists 13 8.70e-01 2.63e-02 9.50e-01
PINK1-PRKN Mediated Mitophagy 17 8.71e-01 2.28e-02 9.50e-01
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 30 8.71e-01 -1.71e-02 9.50e-01
Deadenylation-dependent mRNA decay 49 8.73e-01 -1.32e-02 9.51e-01
TNF signaling 39 8.74e-01 -1.46e-02 9.52e-01
SUMOylation of chromatin organization proteins 53 8.76e-01 -1.24e-02 9.52e-01
Diseases associated with N-glycosylation of proteins 16 8.78e-01 -2.22e-02 9.52e-01
GAB1 signalosome 17 8.79e-01 2.14e-02 9.52e-01
Hyaluronan metabolism 14 8.79e-01 2.35e-02 9.52e-01
G0 and Early G1 27 8.79e-01 -1.69e-02 9.52e-01
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 36 8.80e-01 -1.45e-02 9.52e-01
Interferon gamma signaling 74 8.81e-01 -1.01e-02 9.52e-01
Transport of Mature mRNA Derived from an Intronless Transcript 40 8.82e-01 1.35e-02 9.52e-01
RNA Pol II CTD phosphorylation and interaction with CE 25 8.83e-01 -1.70e-02 9.52e-01
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 25 8.83e-01 -1.70e-02 9.52e-01
TNFR1-induced proapoptotic signaling 11 8.83e-01 2.55e-02 9.52e-01
Signaling by NTRKs 126 8.84e-01 7.53e-03 9.52e-01
Kinesins 39 8.84e-01 1.35e-02 9.52e-01
Signaling by TGF-beta Receptor Complex 65 8.85e-01 1.04e-02 9.52e-01
Inactivation, recovery and regulation of the phototransduction cascade 29 8.85e-01 1.55e-02 9.52e-01
Neutrophil degranulation 429 8.86e-01 4.03e-03 9.52e-01
Pre-NOTCH Expression and Processing 55 8.87e-01 -1.11e-02 9.52e-01
Resolution of D-Loop Structures 31 8.87e-01 1.47e-02 9.52e-01
Attenuation phase 21 8.89e-01 1.76e-02 9.53e-01
Translocation of SLC2A4 (GLUT4) to the plasma membrane 48 8.92e-01 -1.14e-02 9.55e-01
Regulation of MECP2 expression and activity 30 8.92e-01 1.44e-02 9.55e-01
Signaling by PDGFR in disease 16 8.94e-01 1.92e-02 9.56e-01
RNA Polymerase III Transcription Termination 19 8.94e-01 1.76e-02 9.56e-01
G1/S-Specific Transcription 29 8.96e-01 -1.41e-02 9.56e-01
Extension of Telomeres 49 8.96e-01 -1.08e-02 9.56e-01
Methylation 13 8.97e-01 -2.08e-02 9.56e-01
tRNA processing 113 8.97e-01 -7.06e-03 9.56e-01
Constitutive Signaling by AKT1 E17K in Cancer 24 8.97e-01 1.52e-02 9.56e-01
PKA-mediated phosphorylation of CREB 18 9.00e-01 1.70e-02 9.58e-01
Cellular Senescence 123 9.03e-01 -6.37e-03 9.60e-01
Signaling by ERBB2 44 9.05e-01 1.05e-02 9.61e-01
SUMOylation of ubiquitinylation proteins 38 9.06e-01 -1.10e-02 9.63e-01
Formation of Senescence-Associated Heterochromatin Foci (SAHF) 13 9.08e-01 1.86e-02 9.63e-01
Beta defensins 14 9.09e-01 1.76e-02 9.64e-01
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane 20 9.10e-01 -1.46e-02 9.64e-01
Synthesis of glycosylphosphatidylinositol (GPI) 15 9.10e-01 -1.69e-02 9.64e-01
FLT3 Signaling 264 9.14e-01 3.87e-03 9.67e-01
Notch-HLH transcription pathway 26 9.18e-01 -1.17e-02 9.68e-01
Intracellular signaling by second messengers 289 9.18e-01 3.55e-03 9.68e-01
Cargo trafficking to the periciliary membrane 47 9.18e-01 -8.72e-03 9.68e-01
Export of Viral Ribonucleoproteins from Nucleus 31 9.19e-01 1.06e-02 9.68e-01
MAPK targets/ Nuclear events mediated by MAP kinases 29 9.20e-01 -1.08e-02 9.68e-01
Cyclin A/B1/B2 associated events during G2/M transition 23 9.20e-01 1.21e-02 9.68e-01
Phase 0 - rapid depolarisation 27 9.21e-01 -1.11e-02 9.68e-01
FOXO-mediated transcription of cell death genes 14 9.21e-01 -1.54e-02 9.68e-01
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation 12 9.22e-01 1.64e-02 9.68e-01
SHC1 events in ERBB4 signaling 12 9.23e-01 1.62e-02 9.68e-01
Intraflagellar transport 39 9.23e-01 -8.90e-03 9.68e-01
Signaling by Activin 13 9.25e-01 -1.50e-02 9.68e-01
ADORA2B mediated anti-inflammatory cytokines production 105 9.26e-01 5.25e-03 9.68e-01
HDR through MMEJ (alt-NHEJ) 10 9.27e-01 1.68e-02 9.68e-01
Cleavage of the damaged purine 13 9.27e-01 -1.47e-02 9.68e-01
Depurination 13 9.27e-01 -1.47e-02 9.68e-01
Recognition and association of DNA glycosylase with site containing an affected purine 13 9.27e-01 -1.47e-02 9.68e-01
IL-6-type cytokine receptor ligand interactions 17 9.28e-01 1.27e-02 9.68e-01
G-protein mediated events 51 9.28e-01 7.32e-03 9.68e-01
The phototransduction cascade 30 9.31e-01 9.20e-03 9.69e-01
Interleukin-2 signaling 10 9.31e-01 1.59e-02 9.69e-01
Endosomal/Vacuolar pathway 10 9.33e-01 1.53e-02 9.70e-01
MET activates PTK2 signaling 18 9.34e-01 -1.13e-02 9.70e-01
NOTCH4 Intracellular Domain Regulates Transcription 17 9.34e-01 1.16e-02 9.70e-01
SUMOylation 161 9.34e-01 3.77e-03 9.70e-01
Polo-like kinase mediated events 15 9.36e-01 1.21e-02 9.70e-01
TCF dependent signaling in response to WNT 155 9.36e-01 -3.75e-03 9.70e-01
Translation of Replicase and Assembly of the Replication Transcription Complex 12 9.36e-01 1.33e-02 9.70e-01
Glucagon-type ligand receptors 28 9.38e-01 -8.51e-03 9.71e-01
Homologous DNA Pairing and Strand Exchange 39 9.41e-01 -6.85e-03 9.74e-01
HSF1-dependent transactivation 30 9.43e-01 -7.57e-03 9.75e-01
Transport of Mature mRNAs Derived from Intronless Transcripts 41 9.44e-01 -6.37e-03 9.75e-01
Keratan sulfate/keratin metabolism 30 9.45e-01 -7.30e-03 9.75e-01
Disease 1337 9.46e-01 1.13e-03 9.75e-01
PKA activation 16 9.46e-01 -9.77e-03 9.75e-01
Interleukin-37 signaling 20 9.46e-01 8.74e-03 9.75e-01
Interleukin receptor SHC signaling 23 9.51e-01 -7.47e-03 9.78e-01
Synthesis of PIPs at the Golgi membrane 17 9.51e-01 -8.56e-03 9.78e-01
Processing of Intronless Pre-mRNAs 17 9.53e-01 -8.32e-03 9.79e-01
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation 10 9.57e-01 9.86e-03 9.82e-01
Diseases of metabolism 215 9.58e-01 2.11e-03 9.82e-01
Toll Like Receptor 3 (TLR3) Cascade 81 9.58e-01 3.40e-03 9.82e-01
DNA Double Strand Break Response 38 9.58e-01 4.96e-03 9.82e-01
Interleukin-12 signaling 39 9.59e-01 4.76e-03 9.82e-01
MAPK1/MAPK3 signaling 256 9.61e-01 1.79e-03 9.83e-01
Fcgamma receptor (FCGR) dependent phagocytosis 93 9.61e-01 2.92e-03 9.83e-01
Signaling by NTRK2 (TRKB) 23 9.66e-01 5.12e-03 9.87e-01
Glycolysis 68 9.67e-01 -2.92e-03 9.87e-01
Olfactory Signaling Pathway 79 9.67e-01 -2.65e-03 9.87e-01
Transcriptional Regulation by MECP2 56 9.71e-01 -2.84e-03 9.88e-01
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 17 9.71e-01 5.09e-03 9.88e-01
Transport of Ribonucleoproteins into the Host Nucleus 31 9.72e-01 -3.61e-03 9.88e-01
Interactions of Vpr with host cellular proteins 34 9.73e-01 3.42e-03 9.88e-01
p75NTR signals via NF-kB 13 9.73e-01 5.49e-03 9.88e-01
PKA activation in glucagon signalling 16 9.73e-01 -4.81e-03 9.88e-01
RORA activates gene expression 18 9.73e-01 4.53e-03 9.88e-01
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 44 9.74e-01 -2.83e-03 9.88e-01
SUMOylation of RNA binding proteins 43 9.75e-01 -2.76e-03 9.88e-01
BMAL1:CLOCK,NPAS2 activates circadian gene expression 27 9.76e-01 3.39e-03 9.88e-01
Collagen degradation 36 9.76e-01 2.94e-03 9.88e-01
Defects in cobalamin (B12) metabolism 13 9.78e-01 4.39e-03 9.89e-01
PCNA-Dependent Long Patch Base Excision Repair 20 9.79e-01 -3.38e-03 9.90e-01
Post-chaperonin tubulin folding pathway 17 9.82e-01 -3.15e-03 9.92e-01
TRAF6 mediated IRF7 activation 14 9.82e-01 -3.40e-03 9.92e-01
SUMOylation of transcription factors 16 9.86e-01 2.61e-03 9.94e-01
Metabolism of carbohydrates 261 9.86e-01 -6.36e-04 9.94e-01
Phenylalanine and tyrosine metabolism 10 9.88e-01 -2.82e-03 9.94e-01
Scavenging of heme from plasma 24 9.88e-01 -1.77e-03 9.94e-01
SUMOylation of DNA damage response and repair proteins 71 9.89e-01 9.35e-04 9.95e-01
Amino acids regulate mTORC1 46 9.90e-01 1.10e-03 9.95e-01
NEP/NS2 Interacts with the Cellular Export Machinery 30 9.92e-01 1.11e-03 9.96e-01
Gluconeogenesis 30 9.95e-01 6.22e-04 9.98e-01
Circadian Clock 66 9.96e-01 -3.89e-04 9.98e-01
Opioid Signalling 83 9.96e-01 3.37e-04 9.98e-01
Transcriptional Regulation by E2F6 32 9.99e-01 -1.01e-04 1.00e+00
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 11 9.99e-01 -1.21e-04 1.00e+00
RHO GTPase Effectors 236 1.00e+00 1.98e-05 1.00e+00


Detailed Gene set reports



Major pathway of rRNA processing in the nucleolus and cytosol

Major pathway of rRNA processing in the nucleolus and cytosol
648
set Major pathway of rRNA processing in the nucleolus and cytosol
setSize 148
pANOVA 7.55e-15
s.dist -0.37
p.adjustANOVA 1.06e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282
RPS16 -8246
TSR1 -8237
RPS17 -8231
LAS1L -8220
HEATR1 -8214
EXOSC1 -8073
RPP40 -7990
RPS3A -7929
RPS28 -7809
WDR75 -7780
RPL29 -7770
RPS21 -7764
RPS5 -7648
RPS27A -7640
RPS15 -7548
RPS11 -7379
RPS14 -7325
RPL38 -7298
BMS1 -7297

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
TSR1 -8237.0
RPS17 -8231.0
LAS1L -8220.0
HEATR1 -8214.0
EXOSC1 -8073.0
RPP40 -7990.0
RPS3A -7929.0
RPS28 -7809.0
WDR75 -7780.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
BMS1 -7297.0
RPL13A -7282.0
RCL1 -7096.0
RPL24 -7065.0
RPL32 -7023.0
MPHOSPH6 -6988.0
RPL6 -6916.0
RPS10 -6822.5
RIOK3 -6733.0
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
EXOSC9 -6555.0
EMG1 -6502.0
EBNA1BP2 -6480.0
RPL36 -6366.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
NOP14 -5999.0
LTV1 -5990.5
RPL28 -5981.0
RPL35 -5900.0
RPS23 -5865.0
PNO1 -5857.0
WDR12 -5752.0
RPL5 -5749.0
TEX10 -5719.0
IMP4 -5693.0
PWP2 -5683.5
NOC4L -5659.0
RPS19 -5609.0
DDX52 -5552.0
NOL12 -5510.5
RPL37A -5473.0
NOP58 -5436.0
DDX21 -5435.0
DHX37 -5426.0
IMP3 -5333.0
NOL9 -5210.0
UTP6 -5198.0
NIP7 -5163.0
RPL19 -5108.0
UTP15 -4961.0
RPP30 -4931.0
WDR36 -4849.0
FAU -4829.0
RPP25 -4689.0
BOP1 -4674.0
FTSJ3 -4563.0
WDR3 -4529.0
RPL35A -4460.0
C1D -4432.0
RPL13 -4424.0
UTP18 -4374.0
RPS6 -4373.0
RPSA -4027.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
RRP9 -3702.0
DDX49 -3628.0
NOP56 -3482.0
EXOSC4 -3421.0
EXOSC5 -3356.0
WDR43 -3348.0
NCL -3329.0
GNL3 -3174.0
UTP20 -3157.0
FCF1 -2809.0
MTREX -2791.0
RPL7 -2750.0
DCAF13 -2707.0
PELP1 -2654.0
RPL8 -2587.0
RPS18 -2478.0
EXOSC3 -2219.0
NOL11 -1943.0
DDX47 -1644.0
DIS3 -1452.0
RPL23A -1088.0
RIOK1 -1046.0
BYSL -877.0
RIOK2 -834.0
UTP14A -381.5
UTP14C -381.5
ERI1 -324.0
RPL31 -303.0
RPS2 -219.0
SNU13 188.0
UTP11 411.0
RPS27L 522.0
RPL27 706.0
UTP3 843.0
MPHOSPH10 991.0
NOB1 1300.0
TBL3 1340.0
RPL7A 1400.0
UTP4 1419.0
RRP7A 1528.0
EXOSC10 1617.0
PDCD11 1804.0
EXOSC7 2356.0
RRP36 2367.0
RPL37 2677.0
SENP3 2732.5
KRR1 2965.0
EXOSC6 3010.0
RBM28 3020.0
RPS9 3031.0
RPS3 3136.0
PES1 3220.0
ISG20L2 3698.0
FBL 3970.0
EXOSC8 4292.0
RPL3L 4494.0
XRN2 4993.0
RPL22 5158.0
WDR46 5939.0
CSNK1D 6028.0
RRP1 6389.0
NOL6 7692.0
CSNK1E 7737.5
EXOSC2 7761.0
WDR18 7833.0


SRP-dependent cotranslational protein targeting to membrane

SRP-dependent cotranslational protein targeting to membrane
1073
set SRP-dependent cotranslational protein targeting to membrane
setSize 83
pANOVA 2.52e-14
s.dist -0.484
p.adjustANOVA 1.24e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282
RPS16 -8246
RPS17 -8231
SEC61A2 -7949
RPS3A -7929
RPS28 -7809
RPL29 -7770
RPS21 -7764
RPS5 -7648
RPS27A -7640
RPS15 -7548
SSR2 -7472
RPS11 -7379
SPCS3 -7363
RPS14 -7325
RPN2 -7299
RPL38 -7298
RPL13A -7282
SRP72 -7203
RPL24 -7065

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
SEC61A2 -7949.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
SSR2 -7472.0
RPS11 -7379.0
SPCS3 -7363.0
RPS14 -7325.0
RPN2 -7299.0
RPL38 -7298.0
RPL13A -7282.0
SRP72 -7203.0
RPL24 -7065.0
RPL32 -7023.0
SSR4 -6987.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
SRP14 -6394.0
RPL36 -6366.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
RPL35 -5900.0
RPS23 -5865.0
SEC61G -5830.0
RPL5 -5749.0
RPS19 -5609.0
SRP9 -5584.0
RPL37A -5473.0
RPL19 -5108.0
FAU -4829.0
SEC61B -4808.0
SEC11A -4525.0
RPL35A -4460.0
RPL13 -4424.0
RPS6 -4373.0
RPSA -4027.0
SPCS1 -4020.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
SRP19 -3584.0
SSR1 -3579.0
SSR3 -2883.0
SRP54 -2836.0
SEC11C -2812.0
RPL7 -2750.0
SRPRA -2690.0
RPL8 -2587.0
RPS18 -2478.0
RPL23A -1088.0
RPN1 -1071.0
RPL31 -303.0
RPS2 -219.0
RPS27L 522.0
RPL27 706.0
SPCS2 959.0
RPL7A 1400.0
SEC61A1 2087.0
RPL37 2677.0
RPS9 3031.0
RPS3 3136.0
RPL3L 4494.0
RPL22 5158.0
TRAM1 5163.0
DDOST 6465.0
SRPRB 6995.0
SRP68 7282.0


rRNA processing in the nucleus and cytosol

rRNA processing in the nucleus and cytosol
1396
set rRNA processing in the nucleus and cytosol
setSize 155
pANOVA 2.66e-14
s.dist -0.354
p.adjustANOVA 1.24e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282
RPS16 -8246
TSR1 -8237
RPS17 -8231
LAS1L -8220
HEATR1 -8214
EXOSC1 -8073
RPP40 -7990
RPS3A -7929
RPS28 -7809
WDR75 -7780
RPL29 -7770
RPS21 -7764
NAT10 -7652
RPS5 -7648
RPS27A -7640
RPS15 -7548
RPS11 -7379
RPS14 -7325
RPL38 -7298

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
TSR1 -8237.0
RPS17 -8231.0
LAS1L -8220.0
HEATR1 -8214.0
EXOSC1 -8073.0
RPP40 -7990.0
RPS3A -7929.0
RPS28 -7809.0
WDR75 -7780.0
RPL29 -7770.0
RPS21 -7764.0
NAT10 -7652.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
BMS1 -7297.0
RPL13A -7282.0
RCL1 -7096.0
RPL24 -7065.0
RPL32 -7023.0
MPHOSPH6 -6988.0
RPL6 -6916.0
RPS10 -6822.5
RIOK3 -6733.0
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
EXOSC9 -6555.0
EMG1 -6502.0
EBNA1BP2 -6480.0
RPL36 -6366.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
NOP14 -5999.0
LTV1 -5990.5
RPL28 -5981.0
RPL35 -5900.0
RPS23 -5865.0
PNO1 -5857.0
WDR12 -5752.0
RPL5 -5749.0
TEX10 -5719.0
IMP4 -5693.0
PWP2 -5683.5
NOC4L -5659.0
RPS19 -5609.0
DDX52 -5552.0
NOL12 -5510.5
RPL37A -5473.0
NOP58 -5436.0
DDX21 -5435.0
DHX37 -5426.0
NOP10 -5374.0
IMP3 -5333.0
NOL9 -5210.0
UTP6 -5198.0
NIP7 -5163.0
RPL19 -5108.0
UTP15 -4961.0
RPP30 -4931.0
WDR36 -4849.0
FAU -4829.0
RPP25 -4689.0
BOP1 -4674.0
FTSJ3 -4563.0
WDR3 -4529.0
RPL35A -4460.0
C1D -4432.0
RPL13 -4424.0
UTP18 -4374.0
RPS6 -4373.0
RPSA -4027.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
RRP9 -3702.0
DDX49 -3628.0
NOP56 -3482.0
EXOSC4 -3421.0
EXOSC5 -3356.0
WDR43 -3348.0
NCL -3329.0
GNL3 -3174.0
UTP20 -3157.0
FCF1 -2809.0
MTREX -2791.0
RPL7 -2750.0
DCAF13 -2707.0
PELP1 -2654.0
RPL8 -2587.0
RPS18 -2478.0
DIMT1 -2344.0
EXOSC3 -2219.0
NOL11 -1943.0
DDX47 -1644.0
DIS3 -1452.0
RPL23A -1088.0
THUMPD1 -1054.0
RIOK1 -1046.0
BYSL -877.0
RIOK2 -834.0
UTP14A -381.5
UTP14C -381.5
ERI1 -324.0
RPL31 -303.0
RPS2 -219.0
SNU13 188.0
TSR3 320.0
UTP11 411.0
RPS27L 522.0
RPL27 706.0
UTP3 843.0
MPHOSPH10 991.0
NOB1 1300.0
TBL3 1340.0
RPL7A 1400.0
UTP4 1419.0
RRP7A 1528.0
EXOSC10 1617.0
PDCD11 1804.0
EXOSC7 2356.0
RRP36 2367.0
RPL37 2677.0
SENP3 2732.5
KRR1 2965.0
EXOSC6 3010.0
RBM28 3020.0
RPS9 3031.0
RPS3 3136.0
PES1 3220.0
ISG20L2 3698.0
FBL 3970.0
EXOSC8 4292.0
RPL3L 4494.0
XRN2 4993.0
RPL22 5158.0
WDR46 5939.0
CSNK1D 6028.0
RRP1 6389.0
DKC1 7024.0
NOL6 7692.0
CSNK1E 7737.5
EXOSC2 7761.0
GAR1 7789.0
WDR18 7833.0


Response of EIF2AK4 (GCN2) to amino acid deficiency

Response of EIF2AK4 (GCN2) to amino acid deficiency
1040
set Response of EIF2AK4 (GCN2) to amino acid deficiency
setSize 72
pANOVA 1.15e-12
s.dist -0.485
p.adjustANOVA 3.56e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282
RPS16 -8246
RPS17 -8231
RPS3A -7929
RPS28 -7809
RPL29 -7770
RPS21 -7764
RPS5 -7648
RPS27A -7640
RPS15 -7548
ATF4 -7426
RPS11 -7379
RPS14 -7325
RPL38 -7298
RPL13A -7282
RPL24 -7065
RPL32 -7023
EIF2S1 -7018
ATF3 -7015
RPL6 -6916

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
ATF4 -7426.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
EIF2S1 -7018.0
ATF3 -7015.0
RPL6 -6916.0
IMPACT -6882.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
EIF2S2 -6402.0
RPL36 -6366.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
RPL35 -5900.0
RPS23 -5865.0
EIF2S3 -5766.5
RPL5 -5749.0
RPS19 -5609.0
RPL37A -5473.0
RPL19 -5108.0
EIF2AK4 -4948.0
FAU -4829.0
RPL35A -4460.0
RPL13 -4424.0
RPS6 -4373.0
RPSA -4027.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
RPL7 -2750.0
RPL8 -2587.0
RPS18 -2478.0
ASNS -2006.0
RPL23A -1088.0
RPL31 -303.0
RPS2 -219.0
RPS27L 522.0
RPL27 706.0
CEBPB 1323.0
RPL7A 1400.0
CEBPG 2139.0
RPL37 2677.0
RPS9 3031.0
RPS3 3136.0
GCN1 3486.0
RPL3L 4494.0
RPL22 5158.0
TRIB3 5887.0
ATF2 5957.0
DDIT3 6317.0


Peptide chain elongation

Peptide chain elongation
833
set Peptide chain elongation
setSize 60
pANOVA 1.66e-12
s.dist -0.527
p.adjustANOVA 3.56e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
RPL36 -6366.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
RPL35 -5900.0
RPS23 -5865.0
RPL5 -5749.0
RPS19 -5609.0
RPL37A -5473.0
RPL19 -5108.0
FAU -4829.0
RPL35A -4460.0
RPL13 -4424.0
RPS6 -4373.0
RPSA -4027.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
RPL7 -2750.0
RPL8 -2587.0
RPS18 -2478.0
EEF1A1 -1278.0
RPL23A -1088.0
RPL31 -303.0
RPS2 -219.0
RPS27L 522.0
RPL27 706.0
RPL7A 1400.0
RPL37 2677.0
RPS9 3031.0
RPS3 3136.0
RPL3L 4494.0
RPL22 5158.0
EEF2 6302.0


Eukaryotic Translation Termination

Eukaryotic Translation Termination
365
set Eukaryotic Translation Termination
setSize 63
pANOVA 1.73e-12
s.dist -0.514
p.adjustANOVA 3.56e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
RPL36 -6366.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
RPL35 -5900.0
RPS23 -5865.0
RPL5 -5749.0
RPS19 -5609.0
RPL37A -5473.0
RPL19 -5108.0
FAU -4829.0
GSPT2 -4504.0
RPL35A -4460.0
N6AMT1 -4431.0
RPL13 -4424.0
RPS6 -4373.0
ETF1 -4323.0
RPSA -4027.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
RPL7 -2750.0
RPL8 -2587.0
RPS18 -2478.0
RPL23A -1088.0
RPL31 -303.0
RPS2 -219.0
RPS27L 522.0
RPL27 706.0
RPL7A 1400.0
RPL37 2677.0
RPS9 3031.0
RPS3 3136.0
RPL3L 4494.0
RPL22 5158.0
APEH 5520.0
GSPT1 6438.0


Viral mRNA Translation

Viral mRNA Translation
1353
set Viral mRNA Translation
setSize 60
pANOVA 1.88e-12
s.dist -0.526
p.adjustANOVA 3.56e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
RPL36 -6366.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
RPL35 -5900.0
RPS23 -5865.0
RPL5 -5749.0
RPS19 -5609.0
RPL37A -5473.0
RPL19 -5108.0
FAU -4829.0
RPL35A -4460.0
RPL13 -4424.0
RPS6 -4373.0
RPSA -4027.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
RPL7 -2750.0
RPL8 -2587.0
RPS18 -2478.0
DNAJC3 -2019.0
RPL23A -1088.0
RPL31 -303.0
RPS2 -219.0
RPS27L 522.0
RPL27 706.0
RPL7A 1400.0
RPL37 2677.0
RPS9 3031.0
RPS3 3136.0
RPL3L 4494.0
RPL22 5158.0
GRSF1 7696.0


Selenocysteine synthesis

Selenocysteine synthesis
1093
set Selenocysteine synthesis
setSize 63
pANOVA 2.03e-12
s.dist -0.512
p.adjustANOVA 3.56e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
SEPSECS -6470.0
RPL36 -6366.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
RPL35 -5900.0
RPS23 -5865.0
RPL5 -5749.0
RPS19 -5609.0
RPL37A -5473.0
RPL19 -5108.0
FAU -4829.0
EEFSEC -4655.0
RPL35A -4460.0
RPL13 -4424.0
RPS6 -4373.0
SECISBP2 -4050.0
RPSA -4027.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
RPL7 -2750.0
RPL8 -2587.0
RPS18 -2478.0
RPL23A -1088.0
RPL31 -303.0
RPS2 -219.0
RPS27L 522.0
RPL27 706.0
RPL7A 1400.0
RPL37 2677.0
RPS9 3031.0
RPS3 3136.0
RPL3L 4494.0
RPL22 5158.0
PSTK 7348.0
SARS1 7350.0


Metabolism

Metabolism
655
set Metabolism
setSize 1845
pANOVA 2.7e-12
s.dist 0.0997
p.adjustANOVA 3.92e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
NEU1 8176.0
PPIP5K1 8159.0
OPLAH 8158.0
SLC19A2 8155.0
RXRB 8151.0
SLC37A2 8145.0
ABCB4 8143.0
GK 8138.5
GK3P 8138.5
PPT2 8132.5
PAPSS1 8121.0
IMPA2 8120.0
PITPNM2 8100.0
ASS1 8096.0
CYP2A13 8073.0
CYP2A6 8073.0
CYP2A7 8073.0
ACACB 8064.0
NUDT7 8063.0
SULT2A1 8062.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NEU1 8176.0
PPIP5K1 8159.0
OPLAH 8158.0
SLC19A2 8155.0
RXRB 8151.0
SLC37A2 8145.0
ABCB4 8143.0
GK 8138.5
GK3P 8138.5
PPT2 8132.5
PAPSS1 8121.0
IMPA2 8120.0
PITPNM2 8100.0
ASS1 8096.0
CYP2A13 8073.0
CYP2A6 8073.0
CYP2A7 8073.0
ACACB 8064.0
NUDT7 8063.0
SULT2A1 8062.0
PPM1K 8055.0
SGMS1 8040.0
ALAS1 8037.0
ALAD 8036.0
PLA2G6 8032.0
HMOX2 8031.0
MGLL 8020.0
SLC2A1 8017.0
OGDH 8010.0
PPARA 7997.0
GMPS 7992.0
PRKD1 7988.0
AZIN2 7979.0
GPAM 7972.0
BPNT1 7970.0
GBE1 7961.0
ACOT7 7952.0
SLCO1A2 7943.0
ACSM1 7940.0
AHCYL1 7929.0
AKR1D1 7924.0
STXBP1 7922.0
TXNRD1 7917.0
ACSL6 7907.5
PHKG2 7896.0
COQ7 7888.0
SELENOI 7885.0
EPHX1 7880.0
GSTO1 7872.0
ADCY4 7870.0
GGT5 7852.0
DGAT2 7843.0
CHST15 7804.0
GSR 7801.0
SLC5A6 7796.0
GOT1 7788.0
SLC27A2 7786.0
ACSL1 7784.0
HSD17B8 7780.0
SCAP 7769.0
TPMT 7768.0
SIN3A 7728.0
AGRN 7727.0
CYP1B1 7721.0
NAMPT 7697.0
RAPGEF4 7690.0
GYS1 7689.0
NEU3 7685.0
MTMR3 7682.0
CDIPT 7681.0
GNB3 7673.0
HAO2 7672.0
ACAA2 7671.0
DPYD 7658.0
PAPSS2 7656.0
OSBPL1A 7651.0
ACOX2 7644.0
GDPD1 7639.0
OSBPL9 7624.0
PPP1CC 7613.0
LDHC 7609.0
CD36 7608.0
ABCB7 7604.0
PCCA 7601.0
ALDH1L1 7595.0
FAM120B 7582.0
SRR 7575.0
GUSB 7571.0
BSG 7570.0
GOT2 7568.0
PFKL 7566.0
SLC2A2 7562.0
PPIP5K2 7553.0
PSMB8 7523.0
ACOT1 7508.5
ACOT2 7508.5
SLC44A1 7506.0
GBA2 7505.0
CA2 7502.0
HSD17B4 7497.0
MIGA1 7495.0
ESRRA 7493.0
SYNJ1 7489.0
NDUFA10 7483.0
PHYKPL 7482.0
LIPE 7475.0
CACNA1D 7472.0
PDHX 7471.0
ADCY8 7470.0
ACO2 7469.0
PDHB 7468.0
AKR7L 7460.0
PIK3R1 7450.0
DMGDH 7433.0
SLC22A1 7430.0
PIP5K1C 7429.0
ADCY6 7405.0
COX10 7392.0
OSBPL6 7390.0
FMO1 7389.0
PLPP3 7387.5
PTPN13 7381.0
OAZ3 7380.0
DEGS1 7375.0
CRAT 7368.0
UGCG 7366.0
PKLR 7362.0
CS 7355.0
SARS1 7350.0
PSTK 7348.0
SLC35B2 7343.0
MTHFD1L 7328.0
AIMP2 7324.0
DLAT 7320.0
CKMT1A 7304.5
HIBCH 7300.0
GNAI2 7291.0
HADHB 7290.0
RGL1 7289.0
HGD 7287.0
PPARGC1A 7286.0
NUDT5 7278.0
PLA2G12A 7271.0
PPARD 7270.0
SLC25A28 7261.0
ACOX1 7255.0
RDH11 7225.5
TM7SF2 7221.0
NCOA1 7218.0
PTGES2 7214.0
MECR 7210.0
PPA2 7187.0
SYNJ2 7186.0
CYP4A11 7182.5
CYP4A22 7182.5
CYP4F11 7182.5
CYP4F12 7182.5
HK1 7172.0
HPD 7170.0
CACNB2 7168.0
G6PC3 7163.0
MAT2B 7160.0
CYP3A4 7151.0
CYP3A43 7151.0
CYP3A5 7151.0
CYP3A7 7151.0
GLUD1 7147.5
GLUD2 7147.5
FDFT1 7140.0
ITPR3 7138.0
HK2 7136.0
KYAT3 7134.0
SMPD1 7133.0
SLC52A3 7132.0
NDUFA8 7131.0
NDUFA12 7130.0
KDSR 7127.0
SLCO1B1 7114.0
SLCO1B3 7114.0
ME3 7099.0
MVK 7089.0
RAB14 7078.0
RAPGEF3 7075.0
DLST 7073.0
CA4 7059.0
ACSF3 7053.0
ACOT13 7051.0
PTGR2 7049.5
PHYH 7045.0
SLC27A5 7037.0
MIGA2 7028.0
CTH 7025.0
SPR 7022.0
MT-CYB 7011.0
ACADVL 7006.0
NDST2 7004.5
NDUFAB1 6996.0
CSPG4 6993.0
ALDH3A2 6988.0
MVD 6987.0
GCK 6985.0
LRAT 6979.0
ECSIT 6963.0
UQCRC1 6960.0
ACER2 6955.0
ITPR1 6954.0
OXCT1 6953.0
HAGH 6949.0
MCCC2 6930.0
ELOVL1 6929.0
NUDT11 6928.0
SERINC3 6922.0
THEM4 6916.0
PISD 6915.0
DDHD1 6907.0
CIAO3 6903.0
FAHD1 6902.0
HEXB 6896.0
PCYT2 6881.0
THTPA 6880.0
NMRAL1 6858.0
ADRA2C 6852.0
ALAS2 6834.0
L2HGDH 6828.0
DGAT1 6818.0
PLBD1 6813.0
ECI1 6811.0
HMGCS2 6810.0
SLC25A27 6807.0
ST3GAL6 6802.0
AUH 6798.0
SLC27A1 6792.0
NNT 6791.0
APOC2 6777.5
ARSB 6768.0
AMACR 6750.0
NUP155 6749.0
PLCD3 6748.0
MCEE 6734.0
SMPD2 6732.0
ABHD14B 6728.0
DHTKD1 6727.0
PRPS1 6718.0
CYP4F2 6710.0
LIPH 6703.0
MMAB 6701.0
PANK1 6687.0
NDST1 6686.0
D2HGDH 6672.0
RETSAT 6670.0
MCCC1 6666.0
NAPRT 6662.0
AK4 6653.0
ADK 6650.0
ADCY9 6648.0
STARD7 6643.0
BDH1 6632.0
CBS 6623.5
CBSL 6623.5
MTMR14 6619.0
PTDSS2 6618.0
PSME1 6608.0
NAALAD2 6593.0
CIDEA 6565.0
CKMT2 6560.0
BCKDK 6559.0
PAH 6547.0
ACSS3 6546.0
ADH7 6545.0
GPC3 6542.0
ACOT11 6541.0
UROC1 6538.0
SLC26A1 6532.0
KCNC2 6530.0
PFKP 6516.0
NDUFV1 6489.0
LRP12 6488.0
ATP5F1B 6480.0
GPD1L 6475.0
PLCD1 6467.0
B3GALT6 6461.0
ACAD9 6453.0
CPT1B 6451.0
SLC25A20 6449.0
ITPKB 6447.0
COX5B 6442.0
SDC3 6440.0
ABCD1 6427.0
MMAA 6426.0
CHPT1 6423.0
PNPO 6410.0
FTCD 6406.0
VAMP2 6400.5
BCKDHB 6380.0
HADHA 6375.0
PLCE1 6370.0
KARS1 6365.0
B4GAT1 6339.0
KYNU 6336.0
PRKG2 6322.0
CAV1 6314.0
MTM1 6305.0
FUT11 6301.0
IDH3G 6298.0
DCTD 6296.0
ALOX12 6295.0
MARS1 6293.0
ABCB11 6290.0
FIG4 6289.0
GNPAT 6274.0
MGST3 6268.0
LPCAT1 6266.0
SLC25A37 6264.0
ACAT1 6251.0
PNPLA6 6241.0
TAZ 6238.0
NOS3 6235.0
INPP5E 6233.0
SLC35D1 6230.0
GNA11 6218.0
CIAPIN1 6211.0
NDUFA9 6209.0
PFKFB1 6194.0
NUP50 6188.0
PSMF1 6184.0
CHP1 6183.0
TK1 6181.0
HYAL2 6167.0
ATP5F1D 6163.0
MT-CO1 6162.0
LDHB 6149.5
SLC25A12 6148.0
GSTM2 6146.0
SLC9A1 6140.0
MAPKAPK2 6139.0
TRAP1 6126.0
ACAA1 6125.0
DPYS 6124.0
SDHC 6123.0
NDUFB10 6086.0
SCD 6085.0
HELZ2 6066.0
SLC52A1 6063.5
SLC52A2 6063.5
ESYT1 6061.0
RIMKLA 6059.0
STARD3 6047.0
B3GALT2 6029.0
GLYAT 6027.0
COX5A 6026.0
EHHADH 6024.0
IDH2 6021.0
CD38 6012.0
COX4I1 6009.0
POLD1 6006.0
ARSL 5997.0
NAGLU 5992.0
ACADM 5984.0
PLA2G3 5983.0
SHMT2 5982.0
SLC25A15 5980.0
ACADL 5978.0
ADSL 5973.0
MTMR4 5959.0
SPHK2 5954.0
MTARC2 5951.0
PIAS4 5949.0
ST3GAL2 5935.0
CYP2S1 5928.0
IMPDH1 5924.0
MBOAT7 5900.0
COX18 5890.0
TRIB3 5887.0
NR1H4 5883.0
GNG8 5873.0
PPCDC 5868.0
ABHD3 5864.0
FABP3 5858.0
SPTLC3 5843.0
ADA 5832.0
NDC1 5827.0
HADH 5813.0
APOA5 5800.0
NUP58 5787.0
BAAT 5784.0
CYP26B1 5783.0
PYCR2 5775.5
SLC25A19 5771.0
MDH1 5761.0
ETFB 5756.0
GART 5752.0
UPB1 5745.0
PANK4 5739.0
PLA2G15 5737.0
SPNS2 5733.0
HSD17B3 5727.0
PPP2R5D 5723.0
OSBPL2 5717.0
ACSS2 5711.0
ELOVL5 5710.0
NUP133 5700.0
NAT8L 5686.0
NADK2 5681.0
ABCD4 5673.0
SRD5A3 5664.0
PRKD2 5653.0
SDHB 5629.0
EPHX2 5626.0
CPT2 5615.0
NDUFS5 5612.0
PTPMT1 5611.0
PI4KA 5609.0
GNA14 5590.0
ATP5MC3 5582.0
MT-ND1 5579.0
IDO2 5575.0
NDUFB7 5573.0
SLC35D2 5569.5
PITPNM1 5555.0
CPNE7 5543.0
GLTP 5539.0
CHKB 5535.0
NDUFV3 5524.0
PLEKHA5 5521.0
TSPO 5508.0
ENTPD4 5505.0
MT-ATP8 5500.0
SPHK1 5497.0
GDPD3 5492.0
MTHFD1 5481.0
NDUFAF7 5479.0
IQGAP1 5465.0
NUDT19 5464.0
DPEP3 5463.0
LHPP 5454.0
FUT4 5450.0
POR 5441.0
NCOA3 5428.0
TTPA 5425.0
CPOX 5413.0
GLRX5 5404.0
HDAC3 5383.0
TKFC 5376.0
ETFDH 5372.0
SULT2B1 5346.0
COQ10A 5345.0
APOA2 5339.0
LPIN2 5328.0
LPL 5325.0
NCOA2 5324.0
GNG12 5320.0
MDH2 5314.0
FLAD1 5296.0
HSD17B11 5290.0
B4GALT7 5289.0
MED20 5287.0
MED11 5275.0
FABP1 5273.0
PCK2 5270.0
ETFA 5269.0
ABCC1 5260.0
LRP8 5255.0
CPT1A 5252.0
CA14 5251.0
KPNB1 5247.0
NQO2 5239.0
AHR 5235.5
AGPAT3 5234.0
ISCU 5231.0
RBP1 5230.0
SULT1E1 5228.5
NUDT12 5225.0
CPTP 5212.0
GUK1 5202.0
BPHL 5199.0
LPIN3 5191.0
APRT 5190.0
VDR 5181.0
PON2 5161.0
RPL22 5158.0
CERS5 5142.0
AGPAT2 5125.0
RAB5A 5118.0
GCH1 5114.0
AGMAT 5096.0
PARP14 5095.0
CSNK2B 5077.0
ITPR2 5073.0
MTHFD2L 5050.0
AK2 5044.0
NCOR2 5040.0
ALDH7A1 5036.0
PDPR 5035.0
GCKR 5033.0
PPP1CA 5029.0
PSMB9 5019.0
OSBPL3 4992.0
LTA4H 4990.0
B3GNT7 4989.0
NDUFB6 4983.0
OTC 4960.0
FITM2 4958.0
IDH3A 4957.0
CYP7A1 4954.0
ST3GAL3 4940.0
MT-ND5 4937.0
CA7 4924.0
IPMK 4921.0
INPP4B 4919.0
IDH3B 4913.0
INPPL1 4912.0
GNAI1 4905.0
AHCY 4901.0
NT5C3A 4888.0
CYC1 4883.0
MT-ND2 4879.0
TIMMDC1 4862.0
ARSG 4846.0
ESYT3 4844.0
ANKRD1 4842.0
INPP5A 4841.0
HMGCS1 4840.0
SERPINA6 4838.0
NUDT13 4824.0
ACOT6 4818.0
GLP1R 4816.0
NADK 4808.0
SPTLC1 4801.0
MTMR2 4800.0
PSAP 4789.0
SLC10A1 4785.0
GAA 4773.0
MT-ND6 4767.0
TDO2 4761.0
CA12 4759.0
PRKAR1A 4751.0
MLYCD 4748.0
PARP9 4747.0
PON1 4745.0
MMACHC 4740.0
ALDH3B1 4733.0
ACADS 4701.0
CYP21A2 4683.0
PRODH 4680.5
APOA4 4672.0
FBP1 4657.0
HPSE 4653.0
HSD17B1 4651.0
ACY1 4649.5
LPGAT1 4643.0
BGN 4642.0
FH 4639.0
SDC4 4637.0
HIBADH 4633.0
MT-ATP6 4629.0
SBF1 4623.0
ITPA 4619.0
IARS1 4606.0
NHLRC1 4600.0
ACSF2 4566.0
CHPF2 4563.0
PLA2G4C 4558.0
ETNK1 4555.0
PIK3R3 4535.5
QDPR 4524.0
NUP98 4522.0
PCCB 4518.0
COQ9 4517.0
PRKACA 4516.0
NUP93 4512.0
ENPP1 4507.0
NCAN 4501.0
PSMD13 4498.0
RPL3L 4494.0
MCAT 4486.0
PLAAT3 4482.0
PARP16 4481.0
LPCAT4 4480.0
COASY 4460.0
MBOAT2 4446.0
BTD 4442.0
MPC2 4435.0
SIN3B 4433.0
PLA2G4F 4411.0
BMX 4404.0
ENTPD5 4385.0
MT-ND4 4382.0
NDUFS3 4380.0
NDOR1 4367.0
ADCY5 4361.0
CYP27A1 4354.0
SLC5A5 4347.0
PIK3R4 4339.0
PDHA1 4337.0
CYP2C18 4328.5
ELOVL2 4317.0
IP6K3 4313.0
PPCS 4307.0
NR1D1 4304.0
COX11 4280.0
GSS 4276.0
CAD 4271.0
TCN2 4268.0
CHST7 4266.0
FABP12 4262.0
FA2H 4252.0
DNPH1 4246.0
CYGB 4243.0
CRYL1 4217.0
CHDH 4204.0
AIP 4203.0
SAMHD1 4197.0
PAOX 4192.5
CERK 4167.0
ORMDL2 4164.0
MORC2 4155.0
ACBD5 4146.0
GBA3 4143.0
HK3 4114.0
PSMD12 4108.0
ABHD4 4098.0
TACO1 4096.0
PDK4 4094.0
AASS 4076.0
MED30 4073.0
NDUFB11 4068.0
ELOVL3 4059.0
CPS1 4058.0
HAL 4053.0
FMO2 4047.0
DMAC2L 4044.0
GYG1 4039.0
SLC46A1 4034.0
GCAT 4033.0
NFYC 4019.0
GNS 4017.0
THRAP3 4012.0
SLC25A10 4009.5
DNM2 3996.0
MT-CO2 3989.0
ATP5ME 3979.0
NDUFAF3 3956.0
SLC6A12 3944.0
PTGR1 3940.0
BCKDHA 3938.5
SLC25A11 3937.0
ACLY 3933.0
INPP5F 3921.0
PRODH2 3914.0
MRI1 3905.0
BLVRB 3893.0
SLC44A4 3892.0
ENTPD1 3885.0
RFK 3881.0
MT-CO3 3879.0
SRD5A1 3839.0
LYPLA1 3830.0
NDUFS1 3819.0
GCSH 3817.0
ALB 3808.0
PPP2R1A 3805.0
ENOPH1 3801.0
HSPG2 3786.0
IVD 3772.0
AMT 3769.5
UCP2 3761.0
PLD6 3759.0
CNDP2 3758.0
BHMT 3748.0
SLC3A2 3743.0
NMNAT1 3733.0
LIPT2 3725.0
STK11 3719.0
B4GALT1 3685.0
SLC25A14 3669.0
LIAS 3668.0
CYP2U1 3661.0
VDAC1 3653.0
GLB1 3652.0
GGT1 3624.0
CDK19 3619.0
LRP10 3616.0
PI4K2A 3614.0
PLCB3 3610.0
PDSS2 3586.0
SUCLG1 3584.0
GPAT3 3583.0
SLC44A5 3580.0
COQ5 3578.0
ALOXE3 3570.0
CERS4 3565.0
NOSTRIN 3557.0
DEGS2 3556.0
COX6B1 3551.0
NAXD 3541.0
PNP 3539.0
BST1 3532.0
AKT1 3530.0
POM121 3523.5
POM121C 3523.5
DCK 3522.0
VAPB 3515.0
ARG2 3514.0
UPP1 3510.0
NDUFS8 3493.0
COX7A2L 3473.0
ACER3 3467.0
INPP5J 3451.0
UROS 3436.0
SLC25A44 3433.0
ADPGK 3429.0
GMPR 3427.0
AS3MT 3419.0
CDA 3407.0
CIAO1 3399.0
IDO1 3376.0
PLCH2 3374.0
PDK2 3361.0
ATP5PD 3350.0
ANGPTL4 3332.0
CDS2 3330.0
COQ6 3306.0
ALDOC 3305.0
ELOVL7 3264.0
PLCG1 3263.0
HSD11B2 3260.0
GPC4 3253.0
AGPAT1 3237.0
SLC44A2 3226.0
DBT 3223.0
XYLT2 3222.0
B3GALT1 3217.0
ACOT8 3216.0
UGT8 3214.0
UQCRC2 3202.0
CHST2 3199.0
GPX2 3181.0
HEXA 3177.5
CYB5R3 3176.0
GPC2 3173.0
AAAS 3172.0
ACP6 3169.0
MED13 3167.0
MED16 3165.0
GALT 3160.0
CRYM 3157.0
PXMP2 3147.0
RPS3 3136.0
ASAH1 3132.0
PFKFB3 3131.0
CSPG5 3130.0
NQO1 3127.0
SDHA 3123.5
ALDOB 3122.0
PNPLA7 3113.0
MED25 3110.0
NAXE 3109.0
AKR7A3 3107.0
DLD 3101.0
SLC16A1 3094.0
MTMR9 3093.0
NDUFS7 3090.0
SULT1B1 3083.0
HAO1 3075.0
UQCRFS1 3065.0
GSTP1 3048.0
TPST2 3036.0
RPS9 3031.0
TYMS 3027.0
BHMT2 3019.0
CYP4B1 3008.0
PLEKHA1 2999.0
MOGAT2 2998.0
ITPK1 2994.0
MTMR1 2992.0
CYP46A1 2984.0
ATP5PO 2966.5
PDP2 2951.0
PTGS1 2945.0
CA5B 2939.0
ELOVL6 2936.0
SDS 2931.0
NUBP2 2930.0
FABP5 2903.0
NDUFB4 2890.0
FHL2 2888.0
PFKFB2 2887.0
NDUFAF6 2862.0
MMUT 2827.0
EPRS1 2820.0
HS6ST1 2818.0
CACNA2D2 2816.0
PYGB 2807.0
AKAP5 2803.0
B4GALT6 2792.0
GPC1 2787.0
B4GALT2 2782.0
B4GALT4 2769.0
RHCE 2752.5
RHD 2752.5
DIO1 2734.0
SLC25A13 2731.0
PIK3C2G 2726.0
NUP85 2708.0
TBL1X 2701.5
LALBA 2697.0
PCYT1A 2694.0
LSS 2690.0
UBIAD1 2682.0
RPL37 2677.0
HMOX1 2671.0
PTGIS 2632.0
ERCC2 2618.0
UPP2 2616.0
OSBP 2607.0
SLC7A5 2601.0
GNB2 2595.0
GNB1 2583.0
DHCR24 2582.0
ENO2 2577.0
HACL1 2573.0
EBP 2569.5
AMPD3 2560.0
FABP9 2555.0
MTAP 2547.5
CYP8B1 2544.0
ISCA1 2527.0
ACSL5 2484.0
ACOX3 2479.0
APOM 2476.0
MFSD2A 2468.0
ADAL 2466.0
CRLS1 2459.0
COX6A1 2441.0
CHRM3 2433.0
PLEKHA4 2428.0
NDUFA4 2427.0
STAB2 2402.0
SLC22A2 2395.0
NUP153 2394.0
GLS2 2379.0
SLCO2B1 2372.0
SORD 2363.0
FMO3 2351.0
ENTPD3 2340.0
GC 2339.0
GCDH 2330.0
UMPS 2328.0
NEU4 2309.0
SGPP1 2300.0
CPNE6 2292.0
NT5E 2278.0
PIP5K1B 2275.0
PSMC3 2256.0
PSME2 2230.0
NDUFA6 2222.0
NT5C2 2210.0
GPAT4 2166.0
RBP4 2158.0
ENTPD8 2150.0
ADH5 2145.0
NDUFS4 2132.0
GNG7 2130.0
GNB5 2123.0
ACOXL 2122.0
PITPNM3 2118.0
TXN2 2111.0
ARV1 2104.0
HSD17B14 2069.0
PLB1 2066.0
SUMF1 2058.0
COMT 2047.0
SACM1L 2044.0
GDA 2042.0
PDK1 2031.0
NT5M 2013.0
CDS1 1993.0
CYP1A2 1984.0
TIAM2 1970.0
BPNT2 1965.0
DHFR 1944.5
DHFR2 1944.5
GPT 1940.0
TPR 1935.0
PLCG2 1922.0
PLA2G2A 1916.0
FXN 1911.0
ACER1 1906.0
NT5C 1896.0
UCKL1 1893.0
DERA 1883.0
PPP2CB 1876.0
HMGCL 1875.0
NUDT18 1867.0
GSTM4 1859.0
CYP4V2 1840.0
SUCLG2 1833.0
DECR1 1813.0
PIP4K2C 1803.0
PIP5K1A 1793.0
GNG2 1781.0
HMGCR 1772.0
HS3ST3A1 1761.0
NUDT4 1756.5
HSD17B10 1753.0
CHAT 1738.0
MTMR12 1733.0
SLC45A2 1727.0
FDX1 1690.0
SULT4A1 1685.0
PDXK 1638.0
GLDC 1630.0
AMDHD1 1625.0
PPARG 1599.0
HSP90AB1 1597.0
TSPOAP1 1582.0
ACSS1 1581.0
DDAH1 1571.0
PECR 1557.0
MED19 1555.0
SRD5A2 1549.0
PSMB2 1548.0
KCNG2 1519.0
INPP1 1515.0
PSME4 1510.0
PRKAR1B 1495.0
BDH2 1484.0
SCO1 1481.0
PLPP6 1469.0
FITM1 1457.0
ETNPPL 1441.0
GNB4 1440.0
NUP62 1422.0
ACSM4 1420.0
AOC3 1403.0
COQ3 1402.0
RPL7A 1400.0
UCP1 1390.0
BCHE 1382.0
PTGDS 1364.5
TNFAIP8L3 1336.0
CYP4F22 1324.0
AMN 1309.0
NDUFAF4 1307.0
NUDT9 1283.0
MAOB 1278.0
HYKK 1271.0
CA3 1268.0
TECR 1244.0
PODXL2 1242.0
ETHE1 1214.0
INS 1207.5
HS6ST2 1202.0
NDUFAF1 1191.0
CYP11A1 1187.0
BCO1 1128.0
ADI1 1124.0
PSMC1 1107.0
CYP19A1 1077.0
FFAR1 1077.0
TYR 1077.0
AANAT 1063.5
KCNB1 1044.0
NDUFB8 1015.5
UBC 1013.0
ABCC2 1006.0
SLC36A4 997.0
PLIN2 985.0
GNPDA1 966.0
NUP188 957.0
HAAO 944.0
STAR 921.0
PNLIP 915.0
ABO 914.0
B3GAT2 894.0
HACD3 849.0
CIAO2B 845.0
AOC1 786.0
PLAAT1 782.0
THEM5 765.0
TALDO1 753.0
COQ2 749.0
XDH 745.0
CBR1 743.0
RPL27 706.0
ALOX12B 627.0
SHPK 615.5
HMBS 610.0
SUCLA2 608.0
STARD5 594.0
SUOX 589.0
GNMT 585.0
CHST3 565.0
NDUFA13 544.0
CSNK1G2 527.0
RPS27L 522.0
NCOR1 513.0
SGMS2 511.0
SP1 506.0
DGAT2L6 503.0
ARSA 498.0
PPP2CA 497.0
SNAP25 491.0
ELOVL4 485.0
AGPS 484.0
CSGALNACT2 479.0
ADRA2A 478.0
SULT1C2 473.0
CEMIP 447.0
AKR1B1 438.0
POMC 432.0
NUP37 424.0
MPC1 407.0
FABP6 393.5
ST3GAL4 357.0
PLA2G4D 356.0
MID1IP1 349.0
PSMD7 321.0
PANK3 310.0
SLC5A8 302.0
NDST4 263.0
NCOA6 255.0
GLYATL3 246.0
GCG 188.0
RIMKLB 188.0
ACAT2 54.0
IPPK 27.0
HACD4 7.0
CHST14 5.0
PTEN 0.0
PPOX -1.0
PGP -4.0
MED15 -8.0
MAN2B1 -33.5
MMS19 -48.0
CSAD -92.0
TPTE -98.5
TPTE2 -98.5
PLCB4 -100.0
GGCT -116.5
MED13L -127.0
MOGAT1 -129.0
APOE -136.0
GALC -145.0
PC -150.0
PRKAA2 -151.0
PSMB5 -153.0
RRM1 -157.0
SEC24B -161.0
MED7 -167.0
SLC6A11 -176.0
AADAC -188.0
ENO1 -219.0
GNG10 -219.0
RPS2 -219.0
TAT -219.0
PFKM -255.0
PHGDH -257.0
RAE1 -259.0
CGA -264.0
ACBD4 -269.0
RPL31 -303.0
TPH1 -304.0
MOCS3 -315.0
INPP5B -319.0
SERINC5 -323.0
AGK -326.0
NAGS -332.0
PIK3C3 -335.0
RBP2 -340.0
INSIG2 -349.0
SDHD -389.5
GDE1 -397.0
KCNS3 -398.0
ADPRM -403.0
FOLH1 -423.0
ISYNA1 -469.0
ACAD10 -476.0
SERINC4 -479.0
GSTK1 -481.0
UGT2A3 -484.0
AIMP1 -487.0
TECRL -489.0
PLCZ1 -491.0
FAAH -494.0
ACBD6 -500.0
B3GALT5 -504.0
GGPS1 -505.0
PNPLA4 -507.0
KCNJ11 -540.0
HS3ST3B1 -547.0
PDK3 -549.0
ALDH1B1 -557.0
AFMID -564.0
NUP210 -565.0
PLA2G4E -576.0
CA1 -581.0
PSMA5 -604.0
GALE -606.0
SLC37A1 -608.0
PLA2G1B -633.0
PNPLA5 -633.0
TH -720.5
TPO -720.5
UGT3A2 -720.5
CA13 -800.0
SLC19A1 -820.0
INPP4A -824.0
MBTPS2 -837.0
TYRP1 -874.0
CHD9 -885.0
ACMSD -901.0
RUFY1 -910.0
CYP2W1 -912.0
CERS3 -915.0
AGPAT4 -928.0
DBH -942.0
NDUFA3 -953.0
ABHD10 -956.0
PARP6 -973.0
GPX1 -981.0
SLC23A2 -991.0
PLEKHA3 -993.0
CHSY1 -998.0
MGST2 -1004.0
INMT -1055.5
IYD -1079.0
RPL23A -1088.0
B3GAT1 -1126.0
TSHB -1126.0
PSMD3 -1168.0
PSMD11 -1181.0
PAICS -1184.0
NR1H3 -1186.0
OLAH -1201.0
ATP5PF -1203.0
PLCB1 -1249.0
PSPH -1263.0
GALK1 -1270.0
CA5A -1322.0
GK2 -1329.0
GLCE -1342.0
EPM2A -1357.0
NR1H2 -1366.0
ABHD5 -1376.0
MAN2B2 -1433.0
B4GALT3 -1440.0
PIP4K2A -1448.0
SULT1A1 -1455.0
SULT1A2 -1455.0
AGXT2 -1462.0
SMS -1473.0
SLC22A3 -1492.0
ATIC -1526.0
DDC -1527.0
FUT2 -1539.0
PSMC6 -1541.0
PLA2G2F -1548.0
SYT5 -1557.0
AGPAT5 -1570.0
ACOT12 -1585.0
CES2 -1591.0
IDUA -1594.0
IDH1 -1627.0
CREBBP -1636.0
PANK2 -1640.0
GATM -1643.0
SAMD8 -1654.0
MGST1 -1655.0
GGT7 -1675.0
PSMA8 -1679.0
CYP17A1 -1685.0
HS3ST6 -1686.0
CTSA -1693.0
ARG1 -1696.0
RAB4A -1698.0
APOB -1729.0
FABP7 -1750.0
TNFAIP8 -1764.0
UCP3 -1769.0
NUDT1 -1771.0
CHST9 -1774.0
CHST1 -1780.0
GLA -1815.0
UBE2I -1820.0
CARM1 -1862.0
B3GALNT1 -1886.0
ATP5MF -1892.0
PARP10 -1918.0
NDUFB5 -1930.0
DUOX2 -1935.0
GNG11 -1937.0
CHAC1 -1970.0
RXRA -1980.0
STARD3NL -1991.0
MED1 -2004.0
ASNS -2006.0
DBI -2008.0
PIK3R2 -2014.5
NDST3 -2026.0
LCLAT1 -2037.0
DPEP1 -2058.0
APOC3 -2065.5
NFS1 -2085.0
ACSBG2 -2092.0
CYP51A1 -2093.0
ALDH3A1 -2094.0
PSMD1 -2102.0
PMVK -2107.0
EP300 -2111.0
KHK -2119.0
SERINC1 -2128.0
CYP1A1 -2131.0
PGM2 -2150.0
PLCB2 -2167.0
MED17 -2171.5
NDUFV2 -2183.0
PHKA2 -2203.0
STX1A -2228.0
FUT1 -2236.0
COX7B -2241.0
SRM -2260.0
LARS1 -2263.0
ADCY3 -2277.0
PPP1CB -2278.0
CHST12 -2284.0
ODC1 -2302.0
ASPG -2305.0
PSMD2 -2319.0
NME2 -2324.0
ENTPD6 -2327.0
ISCA2 -2335.0
GPS2 -2353.0
SLC19A3 -2361.0
WASL -2377.0
HSD3B7 -2383.0
PFKFB4 -2384.0
PSMA1 -2388.0
ALOX15B -2390.0
RARS1 -2400.0
FDX2 -2403.5
RRM2B -2406.0
FADS2 -2411.0
CERT1 -2435.0
LGMN -2445.0
CERS2 -2467.0
RPS18 -2478.0
SPTLC2 -2485.0
CKB -2496.0
GLUL -2505.0
XYLB -2515.0
MTMR10 -2519.0
B3GNT3 -2523.0
HSD17B2 -2550.0
B4GALT5 -2557.0
PLEKHA8 -2559.0
MAN2C1 -2560.0
PSMA7 -2576.0
RPL8 -2587.0
STARD6 -2592.0
PLD2 -2600.0
ACOT4 -2617.0
GPC6 -2630.0
ME2 -2641.0
NMNAT2 -2651.0
PLA2G5 -2658.0
GPAT2 -2660.0
SMPD3 -2703.0
CYP24A1 -2704.0
PIK3CA -2711.0
UGDH -2712.0
FAR2 -2715.0
MINPP1 -2737.0
RPL7 -2750.0
CEPT1 -2753.0
LRP2 -2756.0
PIK3C2A -2762.0
TBL1XR1 -2764.0
BCAN -2767.0
CYP2R1 -2805.0
SLC26A2 -2832.0
CYP2F1 -2838.0
MMADHC -2847.0
SREBF2 -2861.0
RAP1A -2869.0
HSD17B13 -2870.0
NUP88 -2879.0
CTRB1 -2885.5
CTRB2 -2885.5
AHRR -2888.0
LIPT1 -2889.0
ACAD11 -2890.0
BRIP1 -2904.0
CPNE3 -2918.0
PIP4K2B -2963.0
CHST11 -2967.0
GNG5 -2972.0
ACSM3 -2985.0
ENTPD2 -2996.0
HSCB -3003.0
PLA2G4B -3004.5
PSMC4 -3007.0
UROD -3027.0
NDUFC2 -3052.5
SMPD4 -3098.0
SLC6A8 -3103.5
MT-ND3 -3112.0
PSMD4 -3118.0
NUDT3 -3135.0
ORMDL3 -3146.0
VAC14 -3150.0
ALDH6A1 -3168.0
CSNK2A2 -3177.0
CHST13 -3208.0
UQCR11 -3215.5
PGLS -3223.0
ACADSB -3225.0
AGMO -3234.0
IMPA1 -3238.0
TKT -3243.0
BBOX1 -3284.0
OSBPL10 -3302.0
UCK1 -3319.0
NDUFA11 -3345.5
PSMD6 -3353.0
NUBPL -3355.0
PIPOX -3372.0
NDUFA2 -3380.0
PEMT -3381.0
INPP5K -3389.0
CD320 -3394.0
NDUFS2 -3401.0
PTGS2 -3418.0
PSMC2 -3419.0
PLD3 -3441.0
SLC23A1 -3445.0
MED23 -3449.0
INPP5D -3469.0
BCAT2 -3476.0
DHODH -3496.0
PI4K2B -3521.0
RIDA -3529.0
CACNB3 -3530.0
TGS1 -3538.0
MED10 -3546.0
OCA2 -3562.0
TTR -3574.0
HLCS -3583.0
G6PD -3588.0
CACNA1A -3590.0
ASRGL1 -3599.0
COX7C -3618.0
AK8 -3635.0
TNFRSF21 -3652.0
PSMB3 -3665.0
SMOX -3678.0
PIK3R6 -3686.0
MPST -3696.0
FAH -3704.0
GMPR2 -3708.0
RPS13 -3718.0
ENPP3 -3728.0
PPT1 -3753.0
NME1 -3770.0
OSBPL5 -3773.0
SQLE -3782.0
SULT1A3 -3792.5
SULT1A4 -3792.5
PON3 -3794.0
SDC1 -3814.0
SERINC2 -3821.0
RPL10A -3822.0
AGT -3831.0
MED29 -3833.0
SARDH -3844.0
KMO -3849.0
PSMD8 -3851.0
PNMT -3860.0
PIK3R5 -3873.0
KYAT1 -3903.5
RPIA -3910.0
FUT10 -3918.0
AWAT2 -3928.0
TK2 -3952.0
CARNMT1 -3953.0
ENTPD7 -3961.0
ADIPOR2 -3965.0
RPL3 -3968.0
NAT1 -3974.5
NAT2 -3974.5
GLYCTK -3989.0
MED22 -3992.0
ACAD8 -3994.0
UQCR10 -3998.0
XYLT1 -4000.0
FADS1 -4018.0
RPSA -4027.0
CMBL -4036.0
SECISBP2 -4050.0
PSMD14 -4055.0
NRF1 -4104.0
ARF1 -4106.0
SPTSSA -4118.0
HS3ST5 -4128.0
CSNK2A1 -4141.5
CCNC -4162.0
PRPS2 -4167.0
ALPI -4177.0
PDSS1 -4194.0
ALOX15 -4198.0
SCLY -4215.0
ASL -4221.5
SLC25A21 -4239.0
GLB1L -4268.0
COQ10B -4282.0
PHOSPHO1 -4283.0
PLA2G4A -4306.0
STS -4310.0
ADHFE1 -4312.0
CARNS1 -4324.0
HAS1 -4328.0
VKORC1 -4349.0
HMGCLL1 -4359.0
SMARCD3 -4369.0
RPS6 -4373.0
DARS1 -4385.0
PLAAT5 -4389.0
RPL13 -4424.0
CYP39A1 -4425.0
N6AMT1 -4431.0
SDC2 -4440.0
HACD2 -4442.0
LMBRD1 -4449.0
RPL35A -4460.0
RRM2 -4468.0
PHKG1 -4479.0
SEC24D -4488.0
GNA15 -4495.0
GNG3 -4499.0
NADSYN1 -4517.0
GCLC -4521.0
OAZ1 -4538.0
MAT1A -4559.0
HMMR -4596.0
FECH -4603.0
NSDHL -4612.0
NUP35 -4632.0
NUP107 -4634.0
EEFSEC -4655.0
AK9 -4676.0
MTF1 -4679.0
PLPP2 -4680.0
DSEL -4682.0
NMRK1 -4705.0
MTHFR -4706.0
ABCC8 -4720.0
MED4 -4721.0
ACSL4 -4736.0
DAO -4749.0
ADCY2 -4754.0
PLPP1 -4758.0
GYS2 -4766.0
ITPKC -4772.0
GLIPR1 -4774.0
ESYT2 -4775.0
APOA1 -4811.0
ST6GALNAC6 -4815.5
B4GALNT1 -4824.0
NDUFAF5 -4827.0
FAU -4829.0
PGM1 -4856.0
MTHFS -4859.5
CYP26A1 -4873.0
GPI -4891.0
CHPF -4909.0
NUP54 -4913.0
CYP27B1 -4916.0
ARSK -4920.0
PIK3CG -4924.0
MTHFD2 -4932.0
MED24 -4941.0
DDO -4966.0
LPCAT2 -4982.0
MARCKS -5000.0
ACOT9 -5006.0
UQCRB -5007.0
ADCY1 -5008.0
CBR4 -5009.0
CHSY3 -5014.0
NUDT15 -5027.0
MBOAT1 -5042.0
HSD17B7 -5043.0
LRP1 -5044.0
SLC16A8 -5046.0
SGPL1 -5047.0
PSMA2 -5050.5
PCK1 -5060.0
ENO3 -5070.0
PSMA3 -5078.0
GRHL1 -5079.0
SLC22A13 -5093.0
RPL19 -5108.0
SLC35B3 -5115.0
CA6 -5117.0
FASN -5133.0
NOSIP -5142.0
MED6 -5143.0
UQCRH -5150.5
NUP42 -5168.0
PTDSS1 -5228.0
ACP5 -5237.0
CKM -5253.0
AGL -5258.0
SLC44A3 -5267.0
CYP2E1 -5268.0
MED28 -5278.0
VNN1 -5284.0
GNPDA2 -5305.0
PARP8 -5316.0
TMEM126B -5318.0
PYGM -5322.0
PRKD3 -5324.0
ITPKA -5325.0
MSMO1 -5327.0
DHCR7 -5329.0
AASDHPPT -5346.0
DCN -5361.0
CHKA -5389.0
RBKS -5394.0
PLA1A -5396.0
GSTM3 -5409.0
PSMD5 -5412.0
MED21 -5422.0
OGN -5441.0
PGS1 -5459.0
MTMR7 -5471.0
RPL37A -5473.0
CTPS2 -5477.0
TXN -5519.0
CSGALNACT1 -5528.0
SEC13 -5544.0
DPEP2 -5556.0
B3GNT2 -5587.0
LPCAT3 -5589.0
QPRT -5597.0
PSMB4 -5607.0
RPS19 -5609.0
NUP160 -5641.0
SLC25A17 -5644.0
SLC27A3 -5657.0
PIKFYVE -5658.0
PLA2G2D -5665.0
RNLS -5667.0
TPK1 -5669.0
KERA -5674.0
UST -5678.0
NMNAT3 -5680.0
ATP5MG -5696.5
PCTP -5715.0
HS2ST1 -5747.5
RPL5 -5749.0
PI4KB -5750.0
PLD1 -5751.0
ARNT2 -5773.0
AADAT -5792.0
AMD1 -5826.0
CYP26C1 -5829.0
AMPD1 -5835.0
FABP4 -5849.0
GPCPD1 -5855.0
RPS23 -5865.0
TNFAIP8L2 -5866.0
RPL35 -5900.0
FMOD -5918.0
G0S2 -5922.0
PSMB1 -5931.0
PDP1 -5939.0
RPL28 -5981.0
RPS4X -6019.0
GNAS -6021.0
PGAM2 -6024.0
RPL15 -6030.0
B3GALT4 -6036.0
ALDH1A1 -6037.0
IDS -6043.5
MED27 -6062.0
THRSP -6068.0
DGUOK -6071.0
PPP1R3C -6072.0
DUT -6073.0
RORA -6076.0
CMPK1 -6086.0
PCYT1B -6101.0
OAZ2 -6139.0
PIK3CD -6147.0
RPL30 -6152.0
NMRK2 -6159.0
FBP2 -6162.0
FOLR2 -6185.0
DDHD2 -6193.0
RPL23 -6194.0
ZDHHC21 -6207.0
EXT1 -6236.0
PSMB7 -6252.0
EXT2 -6253.0
CA9 -6259.0
PGM2L1 -6262.0
AGXT -6265.0
AACS -6268.0
ASMT -6271.0
RPLP2 -6273.0
LDLR -6289.0
LTC4S -6307.0
INSIG1 -6310.0
PRKACB -6340.0
ABCA1 -6344.0
RPL36 -6366.0
ENPP6 -6377.0
PEX11A -6415.0
PLA2R1 -6447.0
SEPSECS -6470.0
PLD4 -6472.0
ECI2 -6476.0
ADCY7 -6487.0
OAT -6490.0
MED31 -6496.0
MTMR6 -6513.0
HPGD -6516.0
SDSL -6518.0
SLC25A1 -6520.0
COX16 -6527.0
SAR1B -6531.0
MOCS1 -6532.0
HACD1 -6539.0
STARD4 -6556.0
MLX -6572.0
PSMC5 -6575.0
ADIPOR1 -6590.0
PTS -6591.0
TBXAS1 -6596.0
RPS8 -6597.0
GCLM -6619.0
CUBN -6631.0
GM2A -6634.0
IP6K2 -6646.0
RPLP1 -6661.0
CALM1 -6675.0
GBA -6677.0
RPL18A -6679.0
GPD1 -6680.0
RPL18 -6689.0
RPS26 -6692.0
GLS -6702.0
AOX1 -6706.0
SLC16A3 -6714.0
PTGES3 -6729.0
TMLHE -6738.0
GAPDHS -6739.0
NUP43 -6740.0
GPD2 -6755.0
ACSL3 -6761.0
PYGL -6766.0
CDO1 -6767.0
PRELP -6795.0
CD44 -6801.0
SBF2 -6804.0
ALDOA -6806.0
GGT6 -6808.0
RPS10 -6822.5
ST3GAL1 -6845.0
LUM -6863.0
AKR1A1 -6866.0
ABCC5 -6870.0
GDPD5 -6872.0
PFAS -6896.0
RPL6 -6916.0
PRKAG2 -6923.0
DCTPP1 -6925.0
HPGDS -6927.0
NDUFB3 -6948.0
NNMT -6950.0
FPGS -6953.0
ESD -6972.0
PPP2R1B -6978.0
PSMB6 -6996.0
DTYMK -6999.0
PRKAR2A -7003.0
TPST1 -7010.0
RPL32 -7023.0
CH25H -7050.0
RPL24 -7065.0
PIK3C2B -7081.0
AK1 -7082.0
GLO1 -7083.0
PRKCA -7092.0
CERS6 -7111.0
HPRT1 -7123.0
ALDH1L2 -7133.0
HAS2 -7148.0
GSTA5 -7174.0
NFYA -7197.0
CTPS1 -7200.0
NUP205 -7210.0
BLVRA -7225.0
GSTM1 -7232.0
HDC -7234.0
NUP214 -7243.0
AK5 -7249.0
PSMA6 -7250.0
MBTPS1 -7280.0
RPL13A -7282.0
MAT2A -7283.0
GSTZ1 -7293.0
RPL38 -7298.0
CYP4F8 -7313.0
RPS14 -7325.0
HAS3 -7330.0
ARSI -7339.0
FUT7 -7349.0
GLRX -7364.0
MTRR -7367.0
CIDEC -7371.0
RPS11 -7379.0
PYCR1 -7391.0
PSMA4 -7394.0
LDHA -7395.0
VAPA -7396.0
LPIN1 -7406.0
RANBP2 -7410.0
MED26 -7415.5
SAT1 -7423.0
APIP -7433.0
MAOA -7453.0
PNPLA3 -7463.0
PPARGC1B -7464.0
PKM -7469.0
ARNT -7477.0
OSBPL7 -7479.0
SHMT1 -7480.0
GAMT -7485.0
IDI1 -7502.0
ACSBG1 -7512.0
ARNTL -7523.0
ASAH2 -7526.0
MTR -7527.0
OCRL -7541.0
DDAH2 -7547.0
RPS15 -7548.0
SLC37A4 -7558.0
UGP2 -7573.0
COX19 -7585.0
NFYB -7587.0
TPI1 -7603.0
ALOX5AP -7609.0
IL4I1 -7612.0
BCO2 -7616.0
STARD10 -7620.0
PGK1 -7636.0
RPS27A -7640.0
CACNA1E -7644.0
RPS5 -7648.0
OMD -7649.0
PRKAB2 -7660.0
AZIN1 -7688.0
HOGA1 -7689.0
PM20D1 -7706.0
SEC23A -7718.0
AMPD2 -7721.0
MANBA -7725.0
CACNA1C -7730.0
CYP2J2 -7731.0
PITPNB -7740.0
CYP2D6 -7746.5
CYP4F3 -7751.0
RPS21 -7764.0
PLCD4 -7765.0
SLC25A32 -7766.5
RPL29 -7770.0
MOCOS -7784.0
BCAT1 -7785.0
PLCH1 -7799.0
RPS28 -7809.0
GSTT2 -7816.5
GSTT2B -7816.5
MED12 -7822.0
ABCC3 -7823.0
PNPLA8 -7824.0
ETNK2 -7825.0
NEU2 -7830.0
CYP7B1 -7839.0
PSAT1 -7845.0
TST -7850.0
PPAT -7851.0
DUOX1 -7858.0
NPAS2 -7864.0
GPT2 -7865.0
HSD17B12 -7912.0
RPS3A -7929.0
BPGM -7934.0
ADIPOQ -7940.0
UCK2 -7942.0
CTRC -7943.0
SREBF1 -7944.0
ACACA -7955.0
CYB5B -7964.0
ACHE -7966.0
MED9 -7970.0
ME1 -7972.0
AK6 -7987.0
AK7 -7999.0
ACSM5 -8005.0
GAPDH -8006.0
OSBPL8 -8008.0
DHRS7B -8015.0
PHKB -8035.0
RTEL1 -8038.5
PPA1 -8054.0
FLVCR1 -8055.0
MOCS2 -8058.0
DSE -8059.5
AKR1B10 -8061.0
ACAN -8071.0
ALOX5 -8075.0
GRHPR -8084.0
ATP5F1E -8086.0
ASPA -8103.0
ENPP2 -8119.0
CLOCK -8141.0
PLIN1 -8142.0
SEC24A -8147.0
SLC6A7 -8151.0
VCAN -8165.0
PRKAR2B -8171.0
PHKA1 -8179.0
CROT -8187.0
FAR1 -8198.0
GPX4 -8221.0
RPS17 -8231.0
RPS16 -8246.0
RPE -8252.5
RPEL1 -8252.5
MED14 -8255.0
UGT1A1 -8268.0
CES1 -8279.0
RPS15A -8282.0


Eukaryotic Translation Elongation

Eukaryotic Translation Elongation
363
set Eukaryotic Translation Elongation
setSize 63
pANOVA 2.79e-12
s.dist -0.509
p.adjustANOVA 3.92e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
EEF1B2 -7570.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
EEF1B2 -7570.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
RPL36 -6366.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
RPL35 -5900.0
RPS23 -5865.0
RPL5 -5749.0
RPS19 -5609.0
RPL37A -5473.0
RPL19 -5108.0
FAU -4829.0
RPL35A -4460.0
RPL13 -4424.0
RPS6 -4373.0
RPSA -4027.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
RPL7 -2750.0
RPL8 -2587.0
RPS18 -2478.0
EEF1A1 -1278.0
RPL23A -1088.0
RPL31 -303.0
RPS2 -219.0
RPS27L 522.0
RPL27 706.0
EEF1D 748.0
RPL7A 1400.0
RPL37 2677.0
EEF1G 3002.0
RPS9 3031.0
RPS3 3136.0
RPL3L 4494.0
RPL22 5158.0
EEF2 6302.0


Cap-dependent Translation Initiation

Cap-dependent Translation Initiation
149
set Cap-dependent Translation Initiation
setSize 87
pANOVA 9.53e-12
s.dist -0.423
p.adjustANOVA 1.12e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
EIF2B1 -8218.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
EIF2S1 -7018.0
RPL6 -6916.0
RPS10 -6822.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
EIF2B1 -8218.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
EIF2S1 -7018.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
EIF4EBP1 -6482.0
EIF2S2 -6402.0
RPL36 -6366.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
EIF4A2 -5979.0
RPL35 -5900.0
EIF3M -5875.0
RPS23 -5865.0
EIF2S3 -5766.5
RPL5 -5749.0
RPS19 -5609.0
RPL37A -5473.0
EIF3K -5288.0
RPL19 -5108.0
EIF5 -4910.0
FAU -4829.0
EIF2B5 -4627.0
RPL35A -4460.0
RPL13 -4424.0
RPS6 -4373.0
RPSA -4027.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
EIF2B2 -2977.0
RPL7 -2750.0
EIF3H -2613.0
RPL8 -2587.0
RPS18 -2478.0
EIF5B -2410.0
EIF3E -1890.0
EIF3G -1499.0
RPL23A -1088.0
EIF3J -866.0
RPL31 -303.0
RPS2 -219.0
EIF4A1 -181.0
EIF3B -78.0
EIF4E -29.0
EIF3A -12.0
RPS27L 522.0
RPL27 706.0
RPL7A 1400.0
EIF3C 1656.5
EIF3D 2550.0
RPL37 2677.0
EIF3L 2985.0
RPS9 3031.0
RPS3 3136.0
EIF2B3 3266.0
EIF1AX 3460.0
EIF2B4 3594.0
EIF4G1 4151.0
RPL3L 4494.0
RPL22 5158.0
EIF3F 5628.0
EIF4H 7514.0


Eukaryotic Translation Initiation

Eukaryotic Translation Initiation
364
set Eukaryotic Translation Initiation
setSize 87
pANOVA 9.53e-12
s.dist -0.423
p.adjustANOVA 1.12e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
EIF2B1 -8218.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
EIF2S1 -7018.0
RPL6 -6916.0
RPS10 -6822.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
EIF2B1 -8218.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
EIF2S1 -7018.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
EIF4EBP1 -6482.0
EIF2S2 -6402.0
RPL36 -6366.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
EIF4A2 -5979.0
RPL35 -5900.0
EIF3M -5875.0
RPS23 -5865.0
EIF2S3 -5766.5
RPL5 -5749.0
RPS19 -5609.0
RPL37A -5473.0
EIF3K -5288.0
RPL19 -5108.0
EIF5 -4910.0
FAU -4829.0
EIF2B5 -4627.0
RPL35A -4460.0
RPL13 -4424.0
RPS6 -4373.0
RPSA -4027.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
EIF2B2 -2977.0
RPL7 -2750.0
EIF3H -2613.0
RPL8 -2587.0
RPS18 -2478.0
EIF5B -2410.0
EIF3E -1890.0
EIF3G -1499.0
RPL23A -1088.0
EIF3J -866.0
RPL31 -303.0
RPS2 -219.0
EIF4A1 -181.0
EIF3B -78.0
EIF4E -29.0
EIF3A -12.0
RPS27L 522.0
RPL27 706.0
RPL7A 1400.0
EIF3C 1656.5
EIF3D 2550.0
RPL37 2677.0
EIF3L 2985.0
RPS9 3031.0
RPS3 3136.0
EIF2B3 3266.0
EIF1AX 3460.0
EIF2B4 3594.0
EIF4G1 4151.0
RPL3L 4494.0
RPL22 5158.0
EIF3F 5628.0
EIF4H 7514.0


Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
765
set Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
setSize 65
pANOVA 1.98e-11
s.dist -0.481
p.adjustANOVA 2.01e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
RPL36 -6366.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
RPL35 -5900.0
RPS23 -5865.0
RPL5 -5749.0
RPS19 -5609.0
RPL37A -5473.0
RPL19 -5108.0
FAU -4829.0
GSPT2 -4504.0
RPL35A -4460.0
RPL13 -4424.0
RPS6 -4373.0
ETF1 -4323.0
RPSA -4027.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
NCBP1 -3144.0
RPL7 -2750.0
RPL8 -2587.0
RPS18 -2478.0
RPL23A -1088.0
RPL31 -303.0
RPS2 -219.0
RPS27L 522.0
RPL27 706.0
NCBP2 898.0
RPL7A 1400.0
RPL37 2677.0
RPS9 3031.0
RPS3 3136.0
EIF4G1 4151.0
RPL3L 4494.0
RPL22 5158.0
GSPT1 6438.0
UPF1 8167.0


GTP hydrolysis and joining of the 60S ribosomal subunit

GTP hydrolysis and joining of the 60S ribosomal subunit
456
set GTP hydrolysis and joining of the 60S ribosomal subunit
setSize 81
pANOVA 2e-11
s.dist -0.431
p.adjustANOVA 2.01e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
EIF2S1 -7018.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
EIF2S1 -7018.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
EIF2S2 -6402.0
RPL36 -6366.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
EIF4A2 -5979.0
RPL35 -5900.0
EIF3M -5875.0
RPS23 -5865.0
EIF2S3 -5766.5
RPL5 -5749.0
RPS19 -5609.0
RPL37A -5473.0
EIF3K -5288.0
RPL19 -5108.0
EIF5 -4910.0
FAU -4829.0
RPL35A -4460.0
RPL13 -4424.0
RPS6 -4373.0
RPSA -4027.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
RPL7 -2750.0
EIF3H -2613.0
RPL8 -2587.0
RPS18 -2478.0
EIF5B -2410.0
EIF3E -1890.0
EIF3G -1499.0
RPL23A -1088.0
EIF3J -866.0
RPL31 -303.0
RPS2 -219.0
EIF4A1 -181.0
EIF3B -78.0
EIF4E -29.0
EIF3A -12.0
RPS27L 522.0
RPL27 706.0
RPL7A 1400.0
EIF3C 1656.5
EIF3D 2550.0
RPL37 2677.0
EIF3L 2985.0
RPS9 3031.0
RPS3 3136.0
EIF1AX 3460.0
EIF4G1 4151.0
RPL3L 4494.0
RPL22 5158.0
EIF3F 5628.0
EIF4H 7514.0


Formation of a pool of free 40S subunits

Formation of a pool of free 40S subunits
415
set Formation of a pool of free 40S subunits
setSize 71
pANOVA 2.96e-11
s.dist -0.456
p.adjustANOVA 2.77e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
RPL36 -6366.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
RPL35 -5900.0
EIF3M -5875.0
RPS23 -5865.0
RPL5 -5749.0
RPS19 -5609.0
RPL37A -5473.0
EIF3K -5288.0
RPL19 -5108.0
FAU -4829.0
RPL35A -4460.0
RPL13 -4424.0
RPS6 -4373.0
RPSA -4027.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
RPL7 -2750.0
EIF3H -2613.0
RPL8 -2587.0
RPS18 -2478.0
EIF3E -1890.0
EIF3G -1499.0
RPL23A -1088.0
EIF3J -866.0
RPL31 -303.0
RPS2 -219.0
EIF3B -78.0
EIF3A -12.0
RPS27L 522.0
RPL27 706.0
RPL7A 1400.0
EIF3C 1656.5
EIF3D 2550.0
RPL37 2677.0
EIF3L 2985.0
RPS9 3031.0
RPS3 3136.0
EIF1AX 3460.0
RPL3L 4494.0
RPL22 5158.0
EIF3F 5628.0


L13a-mediated translational silencing of Ceruloplasmin expression

L13a-mediated translational silencing of Ceruloplasmin expression
610
set L13a-mediated translational silencing of Ceruloplasmin expression
setSize 79
pANOVA 3.62e-11
s.dist -0.431
p.adjustANOVA 3.18e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
EIF2S1 -7018.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
EIF2S1 -7018.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
EIF2S2 -6402.0
RPL36 -6366.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
EIF4A2 -5979.0
RPL35 -5900.0
EIF3M -5875.0
RPS23 -5865.0
EIF2S3 -5766.5
RPL5 -5749.0
RPS19 -5609.0
RPL37A -5473.0
EIF3K -5288.0
RPL19 -5108.0
FAU -4829.0
RPL35A -4460.0
RPL13 -4424.0
RPS6 -4373.0
RPSA -4027.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
RPL7 -2750.0
EIF3H -2613.0
RPL8 -2587.0
RPS18 -2478.0
EIF3E -1890.0
EIF3G -1499.0
RPL23A -1088.0
EIF3J -866.0
RPL31 -303.0
RPS2 -219.0
EIF4A1 -181.0
EIF3B -78.0
EIF4E -29.0
EIF3A -12.0
RPS27L 522.0
RPL27 706.0
RPL7A 1400.0
EIF3C 1656.5
EIF3D 2550.0
RPL37 2677.0
EIF3L 2985.0
RPS9 3031.0
RPS3 3136.0
EIF1AX 3460.0
EIF4G1 4151.0
RPL3L 4494.0
RPL22 5158.0
EIF3F 5628.0
EIF4H 7514.0


The citric acid (TCA) cycle and respiratory electron transport

The citric acid (TCA) cycle and respiratory electron transport
1265
set The citric acid (TCA) cycle and respiratory electron transport
setSize 150
pANOVA 6.21e-11
s.dist 0.309
p.adjustANOVA 5.13e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
OGDH 8010
LDHC 7609
BSG 7570
NDUFA10 7483
PDHX 7471
ACO2 7469
PDHB 7468
CS 7355
DLAT 7320
PPARD 7270
NDUFA8 7131
NDUFA12 7130
ME3 7099
DLST 7073
MT-CYB 7011
NDUFAB1 6996
ECSIT 6963
UQCRC1 6960
HAGH 6949
FAHD1 6902

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OGDH 8010.0
LDHC 7609.0
BSG 7570.0
NDUFA10 7483.0
PDHX 7471.0
ACO2 7469.0
PDHB 7468.0
CS 7355.0
DLAT 7320.0
PPARD 7270.0
NDUFA8 7131.0
NDUFA12 7130.0
ME3 7099.0
DLST 7073.0
MT-CYB 7011.0
NDUFAB1 6996.0
ECSIT 6963.0
UQCRC1 6960.0
HAGH 6949.0
FAHD1 6902.0
L2HGDH 6828.0
SLC25A27 6807.0
NNT 6791.0
D2HGDH 6672.0
NDUFV1 6489.0
ATP5F1B 6480.0
ACAD9 6453.0
COX5B 6442.0
IDH3G 6298.0
NDUFA9 6209.0
ATP5F1D 6163.0
MT-CO1 6162.0
LDHB 6149.5
TRAP1 6126.0
SDHC 6123.0
NDUFB10 6086.0
COX5A 6026.0
IDH2 6021.0
COX4I1 6009.0
COX18 5890.0
ETFB 5756.0
SDHB 5629.0
NDUFS5 5612.0
ATP5MC3 5582.0
MT-ND1 5579.0
NDUFB7 5573.0
NDUFV3 5524.0
MT-ATP8 5500.0
NDUFAF7 5479.0
ETFDH 5372.0
COQ10A 5345.0
MDH2 5314.0
ETFA 5269.0
PDPR 5035.0
NDUFB6 4983.0
IDH3A 4957.0
MT-ND5 4937.0
IDH3B 4913.0
CYC1 4883.0
MT-ND2 4879.0
TIMMDC1 4862.0
MT-ND6 4767.0
FH 4639.0
MT-ATP6 4629.0
MPC2 4435.0
MT-ND4 4382.0
NDUFS3 4380.0
PDHA1 4337.0
COX11 4280.0
TACO1 4096.0
PDK4 4094.0
NDUFB11 4068.0
DMAC2L 4044.0
MT-CO2 3989.0
ATP5ME 3979.0
NDUFAF3 3956.0
MT-CO3 3879.0
NDUFS1 3819.0
UCP2 3761.0
SLC25A14 3669.0
VDAC1 3653.0
SUCLG1 3584.0
COX6B1 3551.0
NDUFS8 3493.0
COX7A2L 3473.0
PDK2 3361.0
ATP5PD 3350.0
UQCRC2 3202.0
SDHA 3123.5
DLD 3101.0
SLC16A1 3094.0
NDUFS7 3090.0
UQCRFS1 3065.0
ATP5PO 2966.5
PDP2 2951.0
NDUFB4 2890.0
NDUFAF6 2862.0
COX6A1 2441.0
NDUFA4 2427.0
NDUFA6 2222.0
NDUFS4 2132.0
PDK1 2031.0
SUCLG2 1833.0
SCO1 1481.0
UCP1 1390.0
NDUFAF4 1307.0
NDUFAF1 1191.0
NDUFB8 1015.5
SUCLA2 608.0
NDUFA13 544.0
MPC1 407.0
SDHD -389.5
PDK3 -549.0
NDUFA3 -953.0
ATP5PF -1203.0
UCP3 -1769.0
ATP5MF -1892.0
NDUFB5 -1930.0
RXRA -1980.0
NDUFV2 -2183.0
COX7B -2241.0
ME2 -2641.0
NDUFC2 -3052.5
MT-ND3 -3112.0
UQCR11 -3215.5
NDUFA11 -3345.5
NUBPL -3355.0
NDUFA2 -3380.0
NDUFS2 -3401.0
COX7C -3618.0
UQCR10 -3998.0
COQ10B -4282.0
ADHFE1 -4312.0
NDUFAF5 -4827.0
UQCRB -5007.0
SLC16A8 -5046.0
UQCRH -5150.5
TMEM126B -5318.0
ATP5MG -5696.5
PDP1 -5939.0
COX16 -6527.0
SLC16A3 -6714.0
NDUFB3 -6948.0
GLO1 -7083.0
GSTZ1 -7293.0
LDHA -7395.0
COX19 -7585.0
PM20D1 -7706.0
ME1 -7972.0
ATP5F1E -8086.0


Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
764
set Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
setSize 83
pANOVA 1.19e-10
s.dist -0.409
p.adjustANOVA 8.76e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282
RPS16 -8246
RPS17 -8231
UPF2 -8156
RPS3A -7929
SMG7 -7916
RPS28 -7809
RPL29 -7770
RPS21 -7764
SMG6 -7760
RPS5 -7648
RPS27A -7640
RPS15 -7548
RPS11 -7379
RPS14 -7325
RPL38 -7298
RPL13A -7282
RPL24 -7065
RPL32 -7023
RPL6 -6916

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
UPF2 -8156.0
RPS3A -7929.0
SMG7 -7916.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
SMG6 -7760.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
RPL36 -6366.0
SMG5 -6279.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
RPL35 -5900.0
RPS23 -5865.0
RPL5 -5749.0
RPS19 -5609.0
RPL37A -5473.0
RPL19 -5108.0
FAU -4829.0
GSPT2 -4504.0
RPL35A -4460.0
RPL13 -4424.0
UPF3A -4384.0
RPS6 -4373.0
ETF1 -4323.0
MAGOH -4309.0
RPSA -4027.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
NCBP1 -3144.0
RPL7 -2750.0
RPL8 -2587.0
RBM8A -2564.0
RPS18 -2478.0
RPL23A -1088.0
DCP1A -1050.0
RPL31 -303.0
RPS2 -219.0
PPP2CA 497.0
RPS27L 522.0
SMG9 582.0
RPL27 706.0
RNPS1 803.0
NCBP2 898.0
EIF4A3 950.0
RPL7A 1400.0
MAGOHB 1608.0
UPF3B 2124.0
CASC3 2399.0
RPL37 2677.0
PPP2R2A 2684.0
RPS9 3031.0
RPS3 3136.0
PPP2R1A 3805.0
EIF4G1 4151.0
SMG8 4226.0
RPL3L 4494.0
RPL22 5158.0
GSPT1 6438.0
UPF1 8167.0


Nonsense-Mediated Decay (NMD)

Nonsense-Mediated Decay (NMD)
766
set Nonsense-Mediated Decay (NMD)
setSize 83
pANOVA 1.19e-10
s.dist -0.409
p.adjustANOVA 8.76e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282
RPS16 -8246
RPS17 -8231
UPF2 -8156
RPS3A -7929
SMG7 -7916
RPS28 -7809
RPL29 -7770
RPS21 -7764
SMG6 -7760
RPS5 -7648
RPS27A -7640
RPS15 -7548
RPS11 -7379
RPS14 -7325
RPL38 -7298
RPL13A -7282
RPL24 -7065
RPL32 -7023
RPL6 -6916

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
UPF2 -8156.0
RPS3A -7929.0
SMG7 -7916.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
SMG6 -7760.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
RPL36 -6366.0
SMG5 -6279.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
RPL35 -5900.0
RPS23 -5865.0
RPL5 -5749.0
RPS19 -5609.0
RPL37A -5473.0
RPL19 -5108.0
FAU -4829.0
GSPT2 -4504.0
RPL35A -4460.0
RPL13 -4424.0
UPF3A -4384.0
RPS6 -4373.0
ETF1 -4323.0
MAGOH -4309.0
RPSA -4027.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
NCBP1 -3144.0
RPL7 -2750.0
RPL8 -2587.0
RBM8A -2564.0
RPS18 -2478.0
RPL23A -1088.0
DCP1A -1050.0
RPL31 -303.0
RPS2 -219.0
PPP2CA 497.0
RPS27L 522.0
SMG9 582.0
RPL27 706.0
RNPS1 803.0
NCBP2 898.0
EIF4A3 950.0
RPL7A 1400.0
MAGOHB 1608.0
UPF3B 2124.0
CASC3 2399.0
RPL37 2677.0
PPP2R2A 2684.0
RPS9 3031.0
RPS3 3136.0
PPP2R1A 3805.0
EIF4G1 4151.0
SMG8 4226.0
RPL3L 4494.0
RPL22 5158.0
GSPT1 6438.0
UPF1 8167.0


rRNA processing

rRNA processing
1394
set rRNA processing
setSize 176
pANOVA 1.45e-09
s.dist -0.265
p.adjustANOVA 1.01e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282
RPS16 -8246
TSR1 -8237
RPS17 -8231
LAS1L -8220
HEATR1 -8214
EXOSC1 -8073
RPP40 -7990
RPS3A -7929
RPS28 -7809
WDR75 -7780
RPL29 -7770
RPS21 -7764
NAT10 -7652
RPS5 -7648
RPS27A -7640
RPS15 -7548
RPS11 -7379
RPS14 -7325
RPL38 -7298

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
TSR1 -8237.0
RPS17 -8231.0
LAS1L -8220.0
HEATR1 -8214.0
EXOSC1 -8073.0
RPP40 -7990.0
RPS3A -7929.0
RPS28 -7809.0
WDR75 -7780.0
RPL29 -7770.0
RPS21 -7764.0
NAT10 -7652.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
BMS1 -7297.0
RPL13A -7282.0
RCL1 -7096.0
RPL24 -7065.0
RPL32 -7023.0
MPHOSPH6 -6988.0
RPL6 -6916.0
RPS10 -6822.5
RIOK3 -6733.0
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
EXOSC9 -6555.0
EMG1 -6502.0
EBNA1BP2 -6480.0
RPL36 -6366.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
NOP14 -5999.0
LTV1 -5990.5
RPL28 -5981.0
RPL35 -5900.0
RPS23 -5865.0
PNO1 -5857.0
WDR12 -5752.0
RPL5 -5749.0
TEX10 -5719.0
IMP4 -5693.0
PWP2 -5683.5
NOC4L -5659.0
RPS19 -5609.0
DDX52 -5552.0
NOL12 -5510.5
RPL37A -5473.0
NOP58 -5436.0
DDX21 -5435.0
DHX37 -5426.0
NOP10 -5374.0
IMP3 -5333.0
NOL9 -5210.0
UTP6 -5198.0
NIP7 -5163.0
RPL19 -5108.0
UTP15 -4961.0
RPP30 -4931.0
WDR36 -4849.0
FAU -4829.0
RPP25 -4689.0
BOP1 -4674.0
FTSJ3 -4563.0
WDR3 -4529.0
RPL35A -4460.0
C1D -4432.0
RPL13 -4424.0
UTP18 -4374.0
RPS6 -4373.0
RPSA -4027.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
RRP9 -3702.0
DDX49 -3628.0
NOP56 -3482.0
EXOSC4 -3421.0
EXOSC5 -3356.0
WDR43 -3348.0
NCL -3329.0
GNL3 -3174.0
UTP20 -3157.0
TRMT10C -3148.0
MT-ND3 -3112.0
FCF1 -2809.0
MTREX -2791.0
RPL7 -2750.0
DCAF13 -2707.0
PELP1 -2654.0
RPL8 -2587.0
RPS18 -2478.0
DIMT1 -2344.0
EXOSC3 -2219.0
NOL11 -1943.0
DDX47 -1644.0
DIS3 -1452.0
MRM1 -1343.0
RPL23A -1088.0
THUMPD1 -1054.0
RIOK1 -1046.0
BYSL -877.0
RIOK2 -834.0
UTP14A -381.5
UTP14C -381.5
ERI1 -324.0
RPL31 -303.0
RPS2 -219.0
SNU13 188.0
TSR3 320.0
UTP11 411.0
RPS27L 522.0
RPL27 706.0
TFB1M 788.0
UTP3 843.0
MRM2 930.5
MPHOSPH10 991.0
PRORP 1105.5
NOB1 1300.0
TBL3 1340.0
RPL7A 1400.0
UTP4 1419.0
RRP7A 1528.0
EXOSC10 1617.0
HSD17B10 1753.0
PDCD11 1804.0
EXOSC7 2356.0
RRP36 2367.0
RPL37 2677.0
SENP3 2732.5
KRR1 2965.0
EXOSC6 3010.0
RBM28 3020.0
RPS9 3031.0
RPS3 3136.0
PES1 3220.0
MT-ND4L 3569.0
ISG20L2 3698.0
MT-CO3 3879.0
FBL 3970.0
MT-CO2 3989.0
EXOSC8 4292.0
MT-ND4 4382.0
RPL3L 4494.0
MT-ATP6 4629.0
MRM3 4729.0
MT-ND2 4879.0
MT-ND5 4937.0
XRN2 4993.0
RPL22 5158.0
MTERF4 5363.0
MT-ATP8 5500.0
MT-ND1 5579.0
WDR46 5939.0
CSNK1D 6028.0
ELAC2 6048.0
MT-CO1 6162.0
RRP1 6389.0
MT-CYB 7011.0
DKC1 7024.0
NOL6 7692.0
CSNK1E 7737.5
EXOSC2 7761.0
GAR1 7789.0
WDR18 7833.0


Metabolism of lipids

Metabolism of lipids
664
set Metabolism of lipids
setSize 669
pANOVA 2.49e-09
s.dist 0.136
p.adjustANOVA 1.67e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
NEU1 8176.0
RXRB 8151.0
ABCB4 8143.0
GK 8138.5
GK3P 8138.5
PPT2 8132.5
PITPNM2 8100.0
ACACB 8064.0
NUDT7 8063.0
SULT2A1 8062.0
SGMS1 8040.0
ALAS1 8037.0
PLA2G6 8032.0
MGLL 8020.0
PPARA 7997.0
PRKD1 7988.0
GPAM 7972.0
ACOT7 7952.0
SLCO1A2 7943.0
AKR1D1 7924.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NEU1 8176.0
RXRB 8151.0
ABCB4 8143.0
GK 8138.5
GK3P 8138.5
PPT2 8132.5
PITPNM2 8100.0
ACACB 8064.0
NUDT7 8063.0
SULT2A1 8062.0
SGMS1 8040.0
ALAS1 8037.0
PLA2G6 8032.0
MGLL 8020.0
PPARA 7997.0
PRKD1 7988.0
GPAM 7972.0
ACOT7 7952.0
SLCO1A2 7943.0
AKR1D1 7924.0
TXNRD1 7917.0
ACSL6 7907.5
SELENOI 7885.0
GGT5 7852.0
DGAT2 7843.0
SLC27A2 7786.0
ACSL1 7784.0
HSD17B8 7780.0
SCAP 7769.0
SIN3A 7728.0
CYP1B1 7721.0
NEU3 7685.0
MTMR3 7682.0
CDIPT 7681.0
HAO2 7672.0
ACAA2 7671.0
OSBPL1A 7651.0
ACOX2 7644.0
GDPD1 7639.0
OSBPL9 7624.0
PPP1CC 7613.0
CD36 7608.0
PCCA 7601.0
FAM120B 7582.0
ACOT1 7508.5
ACOT2 7508.5
SLC44A1 7506.0
GBA2 7505.0
HSD17B4 7497.0
MIGA1 7495.0
ESRRA 7493.0
SYNJ1 7489.0
LIPE 7475.0
PIK3R1 7450.0
PIP5K1C 7429.0
OSBPL6 7390.0
PLPP3 7387.5
PTPN13 7381.0
DEGS1 7375.0
CRAT 7368.0
UGCG 7366.0
HADHB 7290.0
RGL1 7289.0
PPARGC1A 7286.0
PLA2G12A 7271.0
PPARD 7270.0
ACOX1 7255.0
TM7SF2 7221.0
NCOA1 7218.0
PTGES2 7214.0
MECR 7210.0
SYNJ2 7186.0
CYP4A11 7182.5
CYP4A22 7182.5
CYP4F11 7182.5
CYP3A4 7151.0
FDFT1 7140.0
SMPD1 7133.0
KDSR 7127.0
SLCO1B1 7114.0
SLCO1B3 7114.0
MVK 7089.0
RAB14 7078.0
ACSF3 7053.0
ACOT13 7051.0
PTGR2 7049.5
PHYH 7045.0
SLC27A5 7037.0
MIGA2 7028.0
ACADVL 7006.0
NDUFAB1 6996.0
ALDH3A2 6988.0
MVD 6987.0
ACER2 6955.0
OXCT1 6953.0
ELOVL1 6929.0
THEM4 6916.0
PISD 6915.0
DDHD1 6907.0
HEXB 6896.0
PCYT2 6881.0
DGAT1 6818.0
PLBD1 6813.0
ECI1 6811.0
HMGCS2 6810.0
SLC27A1 6792.0
ARSB 6768.0
AMACR 6750.0
MCEE 6734.0
SMPD2 6732.0
CYP4F2 6710.0
LIPH 6703.0
STARD7 6643.0
BDH1 6632.0
MTMR14 6619.0
PTDSS2 6618.0
CIDEA 6565.0
ACSS3 6546.0
ACOT11 6541.0
GPD1L 6475.0
CPT1B 6451.0
SLC25A20 6449.0
ABCD1 6427.0
MMAA 6426.0
CHPT1 6423.0
HADHA 6375.0
CAV1 6314.0
MTM1 6305.0
ALOX12 6295.0
ABCB11 6290.0
FIG4 6289.0
GNPAT 6274.0
LPCAT1 6266.0
ACAT1 6251.0
PNPLA6 6241.0
TAZ 6238.0
INPP5E 6233.0
MAPKAPK2 6139.0
ACAA1 6125.0
SCD 6085.0
HELZ2 6066.0
ESYT1 6061.0
STARD3 6047.0
EHHADH 6024.0
ARSL 5997.0
ACADM 5984.0
PLA2G3 5983.0
ACADL 5978.0
MTMR4 5959.0
SPHK2 5954.0
PIAS4 5949.0
MBOAT7 5900.0
TRIB3 5887.0
NR1H4 5883.0
ABHD3 5864.0
FABP3 5858.0
SPTLC3 5843.0
HADH 5813.0
APOA5 5800.0
BAAT 5784.0
PLA2G15 5737.0
SPNS2 5733.0
HSD17B3 5727.0
OSBPL2 5717.0
ELOVL5 5710.0
SRD5A3 5664.0
PRKD2 5653.0
EPHX2 5626.0
CPT2 5615.0
PTPMT1 5611.0
PI4KA 5609.0
PITPNM1 5555.0
CPNE7 5543.0
GLTP 5539.0
CHKB 5535.0
PLEKHA5 5521.0
TSPO 5508.0
SPHK1 5497.0
GDPD3 5492.0
NUDT19 5464.0
DPEP3 5463.0
NCOA3 5428.0
HDAC3 5383.0
APOA2 5339.0
LPIN2 5328.0
NCOA2 5324.0
HSD17B11 5290.0
MED20 5287.0
MED11 5275.0
FABP1 5273.0
ABCC1 5260.0
CPT1A 5252.0
KPNB1 5247.0
AHR 5235.5
AGPAT3 5234.0
CPTP 5212.0
LPIN3 5191.0
VDR 5181.0
PON2 5161.0
CERS5 5142.0
AGPAT2 5125.0
RAB5A 5118.0
CSNK2B 5077.0
NCOR2 5040.0
PPP1CA 5029.0
OSBPL3 4992.0
LTA4H 4990.0
FITM2 4958.0
CYP7A1 4954.0
INPP4B 4919.0
INPPL1 4912.0
ARSG 4846.0
ESYT3 4844.0
ANKRD1 4842.0
HMGCS1 4840.0
SERPINA6 4838.0
ACOT6 4818.0
SPTLC1 4801.0
MTMR2 4800.0
PSAP 4789.0
SLC10A1 4785.0
MLYCD 4748.0
PON1 4745.0
ALDH3B1 4733.0
ACADS 4701.0
CYP21A2 4683.0
HSD17B1 4651.0
LPGAT1 4643.0
SBF1 4623.0
ACSF2 4566.0
PLA2G4C 4558.0
ETNK1 4555.0
PIK3R3 4535.5
PCCB 4518.0
PRKACA 4516.0
MCAT 4486.0
PLAAT3 4482.0
LPCAT4 4480.0
MBOAT2 4446.0
SIN3B 4433.0
PLA2G4F 4411.0
BMX 4404.0
CYP27A1 4354.0
PIK3R4 4339.0
ELOVL2 4317.0
NR1D1 4304.0
FABP12 4262.0
FA2H 4252.0
CERK 4167.0
ORMDL2 4164.0
MORC2 4155.0
ACBD5 4146.0
GBA3 4143.0
ABHD4 4098.0
MED30 4073.0
ELOVL3 4059.0
NFYC 4019.0
THRAP3 4012.0
PTGR1 3940.0
ACLY 3933.0
INPP5F 3921.0
SLC44A4 3892.0
SRD5A1 3839.0
ALB 3808.0
PLD6 3759.0
CYP2U1 3661.0
GLB1 3652.0
GGT1 3624.0
CDK19 3619.0
PI4K2A 3614.0
GPAT3 3583.0
SLC44A5 3580.0
ALOXE3 3570.0
CERS4 3565.0
DEGS2 3556.0
VAPB 3515.0
ACER3 3467.0
INPP5J 3451.0
ANGPTL4 3332.0
CDS2 3330.0
ELOVL7 3264.0
HSD11B2 3260.0
AGPAT1 3237.0
SLC44A2 3226.0
ACOT8 3216.0
UGT8 3214.0
GPX2 3181.0
HEXA 3177.5
ACP6 3169.0
MED13 3167.0
MED16 3165.0
ASAH1 3132.0
PNPLA7 3113.0
MED25 3110.0
MTMR9 3093.0
CYP4B1 3008.0
PLEKHA1 2999.0
MOGAT2 2998.0
MTMR1 2992.0
CYP46A1 2984.0
PTGS1 2945.0
ELOVL6 2936.0
FABP5 2903.0
FHL2 2888.0
MMUT 2827.0
PIK3C2G 2726.0
TBL1X 2701.5
PCYT1A 2694.0
LSS 2690.0
PTGIS 2632.0
OSBP 2607.0
DHCR24 2582.0
HACL1 2573.0
EBP 2569.5
FABP9 2555.0
CYP8B1 2544.0
ACSL5 2484.0
ACOX3 2479.0
MFSD2A 2468.0
CRLS1 2459.0
PLEKHA4 2428.0
GC 2339.0
NEU4 2309.0
SGPP1 2300.0
CPNE6 2292.0
PIP5K1B 2275.0
GPAT4 2166.0
ACOXL 2122.0
PITPNM3 2118.0
ARV1 2104.0
HSD17B14 2069.0
PLB1 2066.0
SUMF1 2058.0
SACM1L 2044.0
CDS1 1993.0
CYP1A2 1984.0
TIAM2 1970.0
PLA2G2A 1916.0
ACER1 1906.0
HMGCL 1875.0
GSTM4 1859.0
DECR1 1813.0
PIP4K2C 1803.0
PIP5K1A 1793.0
HMGCR 1772.0
CHAT 1738.0
MTMR12 1733.0
FDX1 1690.0
PPARG 1599.0
TSPOAP1 1582.0
PECR 1557.0
MED19 1555.0
SRD5A2 1549.0
BDH2 1484.0
PLPP6 1469.0
FITM1 1457.0
ETNPPL 1441.0
BCHE 1382.0
PTGDS 1364.5
TNFAIP8L3 1336.0
CYP4F22 1324.0
TECR 1244.0
CYP11A1 1187.0
CYP19A1 1077.0
PLIN2 985.0
STAR 921.0
HACD3 849.0
PLAAT1 782.0
THEM5 765.0
CBR1 743.0
ALOX12B 627.0
STARD5 594.0
CSNK1G2 527.0
NCOR1 513.0
SGMS2 511.0
SP1 506.0
DGAT2L6 503.0
ARSA 498.0
ELOVL4 485.0
AGPS 484.0
AKR1B1 438.0
POMC 432.0
FABP6 393.5
PLA2G4D 356.0
MID1IP1 349.0
NCOA6 255.0
ACAT2 54.0
HACD4 7.0
PTEN 0.0
MED15 -8.0
TPTE -98.5
TPTE2 -98.5
MED13L -127.0
MOGAT1 -129.0
GALC -145.0
PRKAA2 -151.0
SEC24B -161.0
MED7 -167.0
CGA -264.0
ACBD4 -269.0
AGK -326.0
PIK3C3 -335.0
INSIG2 -349.0
GDE1 -397.0
ACAD10 -476.0
TECRL -489.0
FAAH -494.0
ACBD6 -500.0
GGPS1 -505.0
PNPLA4 -507.0
PLA2G4E -576.0
PLA2G1B -633.0
PNPLA5 -633.0
INPP4A -824.0
MBTPS2 -837.0
CHD9 -885.0
RUFY1 -910.0
CERS3 -915.0
AGPAT4 -928.0
GPX1 -981.0
PLEKHA3 -993.0
NR1H3 -1186.0
OLAH -1201.0
GK2 -1329.0
NR1H2 -1366.0
ABHD5 -1376.0
PIP4K2A -1448.0
PLA2G2F -1548.0
AGPAT5 -1570.0
ACOT12 -1585.0
CREBBP -1636.0
SAMD8 -1654.0
CYP17A1 -1685.0
CTSA -1693.0
RAB4A -1698.0
FABP7 -1750.0
TNFAIP8 -1764.0
GLA -1815.0
UBE2I -1820.0
CARM1 -1862.0
B3GALNT1 -1886.0
RXRA -1980.0
STARD3NL -1991.0
MED1 -2004.0
DBI -2008.0
PIK3R2 -2014.5
LCLAT1 -2037.0
DPEP1 -2058.0
ACSBG2 -2092.0
CYP51A1 -2093.0
PMVK -2107.0
EP300 -2111.0
CYP1A1 -2131.0
MED17 -2171.5
PPP1CB -2278.0
GPS2 -2353.0
HSD3B7 -2383.0
ALOX15B -2390.0
FDX2 -2403.5
FADS2 -2411.0
CERT1 -2435.0
LGMN -2445.0
CERS2 -2467.0
SPTLC2 -2485.0
MTMR10 -2519.0
HSD17B2 -2550.0
PLEKHA8 -2559.0
STARD6 -2592.0
PLD2 -2600.0
ACOT4 -2617.0
PLA2G5 -2658.0
GPAT2 -2660.0
SMPD3 -2703.0
CYP24A1 -2704.0
PIK3CA -2711.0
FAR2 -2715.0
CEPT1 -2753.0
LRP2 -2756.0
PIK3C2A -2762.0
TBL1XR1 -2764.0
CYP2R1 -2805.0
SREBF2 -2861.0
HSD17B13 -2870.0
AHRR -2888.0
ACAD11 -2890.0
CPNE3 -2918.0
PIP4K2B -2963.0
ACSM3 -2985.0
PLA2G4B -3004.5
SMPD4 -3098.0
ORMDL3 -3146.0
VAC14 -3150.0
CSNK2A2 -3177.0
AGMO -3234.0
OSBPL10 -3302.0
PEMT -3381.0
INPP5K -3389.0
PTGS2 -3418.0
PLD3 -3441.0
MED23 -3449.0
INPP5D -3469.0
PI4K2B -3521.0
TGS1 -3538.0
MED10 -3546.0
TNFRSF21 -3652.0
PIK3R6 -3686.0
PPT1 -3753.0
OSBPL5 -3773.0
SQLE -3782.0
PON3 -3794.0
AGT -3831.0
MED29 -3833.0
PIK3R5 -3873.0
AWAT2 -3928.0
MED22 -3992.0
FADS1 -4018.0
NRF1 -4104.0
ARF1 -4106.0
SPTSSA -4118.0
CSNK2A1 -4141.5
CCNC -4162.0
ALPI -4177.0
ALOX15 -4198.0
GLB1L -4268.0
PHOSPHO1 -4283.0
PLA2G4A -4306.0
STS -4310.0
HMGCLL1 -4359.0
SMARCD3 -4369.0
PLAAT5 -4389.0
CYP39A1 -4425.0
HACD2 -4442.0
SEC24D -4488.0
NSDHL -4612.0
MTF1 -4679.0
PLPP2 -4680.0
MED4 -4721.0
ACSL4 -4736.0
PLPP1 -4758.0
GLIPR1 -4774.0
ESYT2 -4775.0
APOA1 -4811.0
B4GALNT1 -4824.0
CYP27B1 -4916.0
ARSK -4920.0
PIK3CG -4924.0
MED24 -4941.0
LPCAT2 -4982.0
ACOT9 -5006.0
CBR4 -5009.0
MBOAT1 -5042.0
HSD17B7 -5043.0
SGPL1 -5047.0
GRHL1 -5079.0
FASN -5133.0
MED6 -5143.0
PTDSS1 -5228.0
SLC44A3 -5267.0
CYP2E1 -5268.0
MED28 -5278.0
PRKD3 -5324.0
MSMO1 -5327.0
DHCR7 -5329.0
CHKA -5389.0
PLA1A -5396.0
MED21 -5422.0
PGS1 -5459.0
MTMR7 -5471.0
DPEP2 -5556.0
LPCAT3 -5589.0
SLC25A17 -5644.0
SLC27A3 -5657.0
PIKFYVE -5658.0
PLA2G2D -5665.0
PCTP -5715.0
PI4KB -5750.0
PLD1 -5751.0
ARNT2 -5773.0
FABP4 -5849.0
GPCPD1 -5855.0
TNFAIP8L2 -5866.0
G0S2 -5922.0
MED27 -6062.0
THRSP -6068.0
RORA -6076.0
PCYT1B -6101.0
PIK3CD -6147.0
DDHD2 -6193.0
AACS -6268.0
LTC4S -6307.0
INSIG1 -6310.0
PRKACB -6340.0
ABCA1 -6344.0
ENPP6 -6377.0
PEX11A -6415.0
PLA2R1 -6447.0
PLD4 -6472.0
ECI2 -6476.0
MED31 -6496.0
MTMR6 -6513.0
HPGD -6516.0
SLC25A1 -6520.0
SAR1B -6531.0
HACD1 -6539.0
STARD4 -6556.0
TBXAS1 -6596.0
CUBN -6631.0
GM2A -6634.0
GBA -6677.0
GPD1 -6680.0
PTGES3 -6729.0
GPD2 -6755.0
ACSL3 -6761.0
SBF2 -6804.0
GDPD5 -6872.0
PRKAG2 -6923.0
HPGDS -6927.0
CH25H -7050.0
PIK3C2B -7081.0
CERS6 -7111.0
NFYA -7197.0
MBTPS1 -7280.0
CYP4F8 -7313.0
ARSI -7339.0
CIDEC -7371.0
VAPA -7396.0
LPIN1 -7406.0
MED26 -7415.5
PNPLA3 -7463.0
PPARGC1B -7464.0
ARNT -7477.0
OSBPL7 -7479.0
IDI1 -7502.0
ACSBG1 -7512.0
ARNTL -7523.0
ASAH2 -7526.0
OCRL -7541.0
NFYB -7587.0
ALOX5AP -7609.0
STARD10 -7620.0
PRKAB2 -7660.0
SEC23A -7718.0
CYP2J2 -7731.0
PITPNB -7740.0
CYP2D6 -7746.5
CYP4F3 -7751.0
MED12 -7822.0
ABCC3 -7823.0
PNPLA8 -7824.0
ETNK2 -7825.0
NEU2 -7830.0
CYP7B1 -7839.0
NPAS2 -7864.0
HSD17B12 -7912.0
SREBF1 -7944.0
ACACA -7955.0
ACHE -7966.0
MED9 -7970.0
ME1 -7972.0
OSBPL8 -8008.0
DHRS7B -8015.0
ALOX5 -8075.0
CLOCK -8141.0
PLIN1 -8142.0
SEC24A -8147.0
CROT -8187.0
FAR1 -8198.0
GPX4 -8221.0
MED14 -8255.0


Regulation of expression of SLITs and ROBOs

Regulation of expression of SLITs and ROBOs
1010
set Regulation of expression of SLITs and ROBOs
setSize 133
pANOVA 2.86e-09
s.dist -0.298
p.adjustANOVA 1.82e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282
RPS16 -8246
RPS17 -8231
ELOC -8174
ROBO2 -8163
UPF2 -8156
RPS3A -7929
RPS28 -7809
RPL29 -7770
RPS21 -7764
RPS5 -7648
RPS27A -7640
RPS15 -7548
PSMA4 -7394
RPS11 -7379
RPS14 -7325
RPL38 -7298
RPL13A -7282
PSMA6 -7250
RPL24 -7065

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
ELOC -8174.0
ROBO2 -8163.0
UPF2 -8156.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
PSMA4 -7394.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
PSMA6 -7250.0
RPL24 -7065.0
RPL32 -7023.0
PSMB6 -6996.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
PSMC5 -6575.0
RPL36 -6366.0
RPLP2 -6273.0
PSMB7 -6252.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
PSMB1 -5931.0
RPL35 -5900.0
RPS23 -5865.0
RPL5 -5749.0
RPS19 -5609.0
PSMB4 -5607.0
RPL37A -5473.0
PSMD5 -5412.0
RPL19 -5108.0
PSMA3 -5078.0
PSMA2 -5050.5
FAU -4829.0
GSPT2 -4504.0
RPL35A -4460.0
RPL13 -4424.0
UPF3A -4384.0
RPS6 -4373.0
COL4A5 -4372.0
ETF1 -4323.0
MAGOH -4309.0
PSMD14 -4055.0
RPSA -4027.0
RPL3 -3968.0
ISL1 -3924.0
PSMD8 -3851.0
RPL10A -3822.0
RPS13 -3718.0
PSMB3 -3665.0
LHX2 -3561.0
PSMC2 -3419.0
PSMD6 -3353.0
RBX1 -3219.0
NCBP1 -3144.0
PSMD4 -3118.0
PSMC4 -3007.0
RPL7 -2750.0
RPL8 -2587.0
PSMA7 -2576.0
RBM8A -2564.0
RPS18 -2478.0
PSMA1 -2388.0
PSMD2 -2319.0
PSMD1 -2102.0
ROBO1 -1904.0
PSMA8 -1679.0
PSMC6 -1541.0
LHX4 -1469.0
PSMD11 -1181.0
PSMD3 -1168.0
RPL23A -1088.0
PSMA5 -604.0
CUL2 -316.0
RPL31 -303.0
ZSWIM8 -287.0
RPS2 -219.0
PSMB5 -153.0
PSMD7 321.0
ROBO3 480.0
RPS27L 522.0
LHX3 607.0
RPL27 706.0
RNPS1 803.0
NCBP2 898.0
EIF4A3 950.0
UBC 1013.0
PSMC1 1107.0
RPL7A 1400.0
PSME4 1510.0
PSMB2 1548.0
MAGOHB 1608.0
UPF3B 2124.0
PSME2 2230.0
PSMC3 2256.0
CASC3 2399.0
RPL37 2677.0
DAG1 2723.0
RPS9 3031.0
RPS3 3136.0
HOXA2 3282.0
USP33 3752.0
PSMD12 4108.0
EIF4G1 4151.0
LHX9 4232.0
RPL3L 4494.0
PSMD13 4498.0
PSMB9 5019.0
RPL22 5158.0
SLIT1 5988.0
LDB1 5989.0
PSMF1 6184.0
GSPT1 6438.0
MSI1 6507.0
PSME1 6608.0
PSMB8 7523.0
SLIT2 7657.0


Metabolism of RNA

Metabolism of RNA
657
set Metabolism of RNA
setSize 604
pANOVA 2.49e-08
s.dist -0.133
p.adjustANOVA 1.52e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282
BUD31 -8277
RPS16 -8246
TSR1 -8237
RPS17 -8231
MYC -8227
LAS1L -8220
HEATR1 -8214
SF3A3 -8199
UPF2 -8156
ENPP2 -8119
QTRT2 -8113
EXOSC1 -8073
HNRNPH1 -8040
RPP40 -7990
PPIH -7952
RPS3A -7929
CSTF3 -7917
SMG7 -7916
GTF2H1 -7913

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
BUD31 -8277.0
RPS16 -8246.0
TSR1 -8237.0
RPS17 -8231.0
MYC -8227.0
LAS1L -8220.0
HEATR1 -8214.0
SF3A3 -8199.0
UPF2 -8156.0
ENPP2 -8119.0
QTRT2 -8113.0
EXOSC1 -8073.0
HNRNPH1 -8040.0
RPP40 -7990.0
PPIH -7952.0
RPS3A -7929.0
CSTF3 -7917.0
SMG7 -7916.0
GTF2H1 -7913.0
CDKAL1 -7811.0
RPS28 -7809.0
WDR75 -7780.0
RPL29 -7770.0
RPS21 -7764.0
SMG6 -7760.0
RTRAF -7745.0
HNRNPF -7672.0
TPRKB -7658.0
NAT10 -7652.0
RPS5 -7648.0
RPS27A -7640.0
SNRPD3 -7627.5
APOBEC1 -7613.0
WDR77 -7592.0
TRMT61A -7560.0
APOBEC2 -7555.0
RPS15 -7548.0
PPIL1 -7506.0
ZFP36 -7486.0
POLR2D -7461.0
GTF2H5 -7457.0
RANBP2 -7410.0
PSMA4 -7394.0
RPS11 -7379.0
RPS14 -7325.0
PPIE -7317.0
SRSF5 -7315.0
SMNDC1 -7314.0
PAIP1 -7306.0
RPL38 -7298.0
BMS1 -7297.0
RPL13A -7282.0
PSMA6 -7250.0
NUP214 -7243.0
NUP205 -7210.0
SLU7 -7196.0
SNRNP25 -7143.0
RCL1 -7096.0
PRKCA -7092.0
RPL24 -7065.0
RPL32 -7023.0
CWC15 -7021.0
THOC6 -7012.0
PSMB6 -6996.0
MPHOSPH6 -6988.0
TRMT5 -6970.0
RPL6 -6916.0
TRMT13 -6888.0
PPIL3 -6875.0
PRPF40A -6829.0
RPS10 -6822.5
THG1L -6817.0
CD44 -6801.0
MAPK11 -6774.0
NUP43 -6740.0
ZMAT5 -6736.0
RIOK3 -6733.0
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
CNOT10 -6663.0
RPLP1 -6661.0
SLBP -6655.0
POP5 -6654.0
RPS8 -6597.0
PSMC5 -6575.0
EXOSC9 -6555.0
THOC1 -6514.0
EMG1 -6502.0
ALKBH8 -6484.0
EBNA1BP2 -6480.0
TTC37 -6455.0
NXT1 -6449.0
DDX23 -6407.0
RPL36 -6366.0
SMG5 -6279.0
RPLP2 -6273.0
XRN1 -6263.0
PSMB7 -6252.0
IGF2BP3 -6248.0
RPL23 -6194.0
RPL30 -6152.0
HBS1L -6113.0
PUS3 -6107.0
SRSF3 -6066.0
RPL15 -6030.0
RPS4X -6019.0
NOP14 -5999.0
LTV1 -5990.5
RPL28 -5981.0
EIF4A2 -5979.0
ZC3H11A -5961.5
PSMB1 -5931.0
LSM5 -5924.0
APOBEC3H -5912.0
RPL35 -5900.0
RPS23 -5865.0
FTSJ1 -5861.0
PNO1 -5857.0
DDX6 -5851.0
WDR61 -5781.0
POP7 -5763.0
WDR12 -5752.0
RPL5 -5749.0
SNRNP48 -5745.0
TEX10 -5719.0
IMP4 -5693.0
PWP2 -5683.5
GEMIN2 -5661.0
NOC4L -5659.0
TRMT6 -5651.0
NUP160 -5641.0
RPS19 -5609.0
PRPF4 -5608.0
PSMB4 -5607.0
MAPK14 -5555.0
DDX52 -5552.0
SRSF11 -5549.0
SEC13 -5544.0
NOL12 -5510.5
RPL37A -5473.0
PQBP1 -5466.0
NOP58 -5436.0
DDX21 -5435.0
DHX37 -5426.0
PSMD5 -5412.0
LSM4 -5405.0
TP53RK -5386.0
NOP10 -5374.0
SF3B1 -5370.0
DDX39A -5351.0
IMP3 -5333.0
DDX20 -5321.0
NOL9 -5210.0
GEMIN7 -5204.0
UTP6 -5198.0
NUP42 -5168.0
NIP7 -5163.0
RPL19 -5108.0
PSMA3 -5078.0
PSMA2 -5050.5
CLNS1A -5049.0
HNRNPA3 -5022.0
UTP15 -4961.0
BCAS2 -4951.0
RPP30 -4931.0
NUP54 -4913.0
CWC27 -4911.0
LAGE3 -4890.0
PAN2 -4866.0
WDR36 -4849.0
FAU -4829.0
NXF1 -4803.0
PHAX -4752.0
TRMT12 -4731.0
LSM7 -4729.0
TNFSF13 -4724.0
RPP25 -4689.0
POLR2C -4681.0
BOP1 -4674.0
PPIL6 -4667.0
NUP107 -4634.0
NUP35 -4632.0
GEMIN8 -4630.0
SRSF6 -4629.0
PPIL4 -4622.0
FTSJ3 -4563.0
CNOT4 -4531.0
WDR3 -4529.0
GTF2H2 -4507.5
GSPT2 -4504.0
RPL35A -4460.0
SNRPD1 -4459.0
C1D -4432.0
RPL13 -4424.0
WDR33 -4408.0
RNPC3 -4388.0
UPF3A -4384.0
UTP18 -4374.0
RPS6 -4373.0
PCF11 -4346.0
ETF1 -4323.0
MAGOH -4309.0
TRA2B -4288.0
GEMIN6 -4286.0
DUS2 -4285.0
PRKCD -4252.0
POLR2G -4208.0
TSEN15 -4205.0
PCBP2 -4190.0
PSMD14 -4055.0
METTL14 -4046.0
RPSA -4027.0
SNRPG -4015.0
HSPA8 -3970.0
RPL3 -3968.0
DDX46 -3929.0
SRRT -3902.0
PSMD8 -3851.0
RPL10A -3822.0
RPS13 -3718.0
ZBTB8OS -3706.0
RRP9 -3702.0
PSMB3 -3665.0
METTL1 -3645.0
DDX49 -3628.0
PUS7 -3589.0
LSM3 -3545.0
TGS1 -3538.0
THADA -3532.0
PRMT5 -3512.0
NOP56 -3482.0
EXOSC4 -3421.0
THOC7 -3420.0
PSMC2 -3419.0
GLE1 -3391.0
EXOSC5 -3356.0
PSMD6 -3353.0
WDR43 -3348.0
NCL -3329.0
ISY1 -3295.5
PAPOLA -3280.0
SNRNP200 -3275.0
GNL3 -3174.0
UTP20 -3157.0
DDX42 -3155.0
TRMT10C -3148.0
NCBP1 -3144.0
PSMD4 -3118.0
MT-ND3 -3112.0
GTF2F2 -3055.0
CWC22 -3035.0
WTAP -3021.0
PSMC4 -3007.0
PRPF3 -2927.0
ZNF473 -2914.0
NUP88 -2879.0
PRPF19 -2878.0
IGF2BP2 -2814.0
DDX5 -2813.0
FCF1 -2809.0
MTREX -2791.0
THOC2 -2790.0
RPL7 -2750.0
SRSF1 -2734.0
DCAF13 -2707.0
PRPF38A -2657.0
PELP1 -2654.0
SRSF2 -2590.0
RPL8 -2587.0
PSMA7 -2576.0
RBM8A -2564.0
SNRPD2 -2490.0
PLRG1 -2479.0
RPS18 -2478.0
POLR2L -2471.0
CPSF4 -2453.0
SNRPA -2408.0
PSMA1 -2388.0
CCNH -2363.0
DIMT1 -2344.0
CPSF7 -2334.0
SRRM2 -2320.0
PSMD2 -2319.0
CTU2 -2309.0
POLR2I -2271.0
HNRNPK -2251.0
C2orf49 -2232.0
EXOSC3 -2219.0
SNRNP40 -2214.0
SRSF7 -2197.0
PSMD1 -2102.0
NOL11 -1943.0
SF3B6 -1936.0
PRPF6 -1876.0
THOC5 -1866.0
SNRNP35 -1825.0
CSTF2 -1811.0
SNRPB2 -1742.0
TSEN2 -1709.0
PSMA8 -1679.0
CWC25 -1677.0
ADAT1 -1673.0
DDX47 -1644.0
CNOT2 -1622.0
DDX1 -1572.0
MNAT1 -1564.0
PSMC6 -1541.0
HSPB1 -1531.0
PHF5A -1498.0
DIS3 -1452.0
DNAJC8 -1356.0
LCMT2 -1353.0
MRM1 -1343.0
SUGP1 -1338.0
ZRSR2 -1321.0
CCAR1 -1243.0
PSMD11 -1181.0
PSMD3 -1168.0
IGF2BP1 -1126.0
RPL23A -1088.0
U2SURP -1070.0
POLR2H -1058.0
THUMPD1 -1054.0
DCP1A -1050.0
RIOK1 -1046.0
SNRPC -1045.0
ELAVL1 -955.0
POLR2F -932.0
BYSL -877.0
RIOK2 -834.0
PSMA5 -604.0
POP4 -571.0
U2AF1 -569.5
NUP210 -565.0
CNOT11 -455.0
UTP14A -381.5
UTP14C -381.5
ERI1 -324.0
RBM22 -320.0
RPL31 -303.0
DHX38 -274.0
CLP1 -273.0
RAE1 -259.0
RPS2 -219.0
SNRPE -219.0
URM1 -219.0
EIF4A1 -181.0
RNMT -179.0
RBM17 -160.0
PSMB5 -153.0
NSUN6 -71.0
EIF4E -29.0
PAN3 -13.0
POLDIP3 -9.0
HNRNPM -5.0
SNU13 188.0
AQR 242.0
TSR3 320.0
PSMD7 321.0
UTP11 411.0
NUP37 424.0
PPWD1 426.0
TYW5 430.0
PPP2CA 497.0
RPS27L 522.0
GTF2H3 553.0
SMG9 582.0
RPL27 706.0
SF3B5 715.0
SYMPK 735.0
TFB1M 788.0
RNPS1 803.0
UTP3 843.0
NCBP2 898.0
MRM2 930.5
PRPF31 934.0
CTU1 935.0
EIF4A3 950.0
NUP188 957.0
OSGEP 990.0
MPHOSPH10 991.0
UBC 1013.0
TRMT44 1039.0
PRORP 1105.5
PSMC1 1107.0
RBM5 1159.0
SF3B3 1273.0
ZCRB1 1290.0
NOB1 1300.0
TBL3 1340.0
RPL7A 1400.0
UTP4 1419.0
NUP62 1422.0
CTNNBL1 1424.0
PABPN1 1437.5
SNRPA1 1460.0
U2AF2 1467.0
PSME4 1510.0
RRP7A 1528.0
USP39 1547.0
PSMB2 1548.0
TRIT1 1588.0
MAGOHB 1608.0
EXOSC10 1617.0
CHERP 1618.0
CDC40 1669.0
ACTB 1684.0
TNPO1 1708.0
TRNT1 1725.0
HSD17B10 1753.0
PDCD7 1768.0
PDCD11 1804.0
LSM6 1811.0
GTF2H4 1930.0
TPR 1935.0
EDC4 2001.0
XPO1 2059.0
TSEN54 2074.0
UPF3B 2124.0
TSEN34 2164.0
XPOT 2214.0
PSME2 2230.0
TRDMT1 2232.0
PSMC3 2256.0
PUF60 2268.0
EXOSC7 2356.0
RRP36 2367.0
HSPA1A 2373.5
METTL3 2390.0
NUP153 2394.0
CASC3 2399.0
U2AF1L4 2416.5
TRMT1 2430.0
HNRNPA0 2449.0
POLR2B 2513.0
GPKOW 2516.0
QTRT1 2520.0
SRSF10 2596.0
ERCC2 2618.0
RTCB 2647.0
RPL37 2677.0
PPP2R2A 2684.0
NUP85 2708.0
GTF2F1 2709.0
SENP3 2732.5
ALYREF 2748.0
SYF2 2768.0
EPRS1 2820.0
SRRM1 2836.0
TRMU 2928.0
TRMT10A 2938.0
FUS 2948.0
KRR1 2965.0
DCP1B 2978.0
EXOSC6 3010.0
SRSF4 3011.0
RBM28 3020.0
RPS9 3031.0
TNKS1BP1 3073.0
TFIP11 3096.0
RPS3 3136.0
AAAS 3172.0
PES1 3220.0
SKIV2L 3278.0
SNUPN 3347.0
ZFP36L1 3380.0
SNRPB 3448.0
SARNP 3479.0
POM121 3523.5
POM121C 3523.5
AKT1 3530.0
EDC3 3543.0
CNOT8 3544.0
GTPBP3 3564.0
MT-ND4L 3569.0
CPSF2 3593.0
NUDT21 3672.0
DHX16 3676.0
ISG20L2 3698.0
DHX15 3789.0
PPP2R1A 3805.0
MT-CO3 3879.0
PUS1 3916.0
FYTTD1 3957.0
FBL 3970.0
DHX9 3976.0
MT-CO2 3989.0
SNW1 4003.0
PSMD12 4108.0
EIF4G1 4151.0
GPRC5A 4169.0
SRSF9 4225.0
SMG8 4226.0
TYW1 4287.5
EXOSC8 4292.0
HNRNPR 4294.0
HNRNPA2B1 4375.0
MT-ND4 4382.0
CD2BP2 4387.0
SMN1 4395.5
ADAR 4425.0
MTO1 4449.0
NXF2 4458.0
RPL3L 4494.0
PSMD13 4498.0
NUP93 4512.0
ERCC3 4515.0
NUP98 4522.0
CNOT1 4545.0
POP1 4612.0
MT-ATP6 4629.0
FAM98B 4656.0
YWHAB 4694.0
NT5C3B 4710.0
SF3B2 4713.0
MRM3 4729.0
MT-ND6 4767.0
NSUN2 4779.0
ANP32A 4822.5
TYW3 4832.0
HNRNPU 4859.0
CNOT7 4870.0
MT-ND2 4879.0
MT-ND5 4937.0
CDK7 4949.0
CSTF1 4970.0
TRMT9B 4973.0
GEMIN4 4978.0
CNOT6L 4982.0
XRN2 4993.0
PSMB9 5019.0
CPSF3 5037.0
SART1 5045.0
ELAVL2 5064.0
LSM11 5145.0
RPL22 5158.0
LSM1 5165.0
WDR4 5261.0
GEMIN5 5282.0
MTERF4 5363.0
SF3B4 5375.0
ADAT2 5399.0
SUPT5H 5401.0
XAB2 5426.0
PATL1 5473.0
CRNKL1 5484.0
MT-ATP8 5500.0
RNGTT 5571.0
MT-ND1 5579.0
NUP133 5700.0
KHSRP 5715.0
CNOT3 5744.0
NUP58 5787.0
NDC1 5827.0
HNRNPH2 5828.0
A1CF 5886.0
IGF2 5925.0
WDR46 5939.0
SF3A2 5950.0
CSNK1D 6028.0
ELAC2 6048.0
MAPKAPK2 6139.0
MT-CO1 6162.0
PSMF1 6184.0
NUP50 6188.0
PARN 6220.0
CDC5L 6282.0
POLR2A 6384.0
RRP1 6389.0
GSPT1 6438.0
THOC3 6469.0
ADARB1 6485.0
HNRNPUL1 6548.0
RBMX 6602.5
TRMT11 6607.0
PSME1 6608.0
PRCC 6678.0
NUP155 6749.0
SF1 6765.0
YWHAZ 6876.0
MT-CYB 7011.0
DKC1 7024.0
WBP4 7252.0
SF3A1 7281.0
CNOT6 7360.0
GCFC2 7411.0
PRPF8 7446.0
CPSF1 7491.0
PSMB8 7523.0
CHTOP 7574.0
NOL6 7692.0
CSNK1E 7737.5
EXOSC2 7761.0
GAR1 7789.0
WDR18 7833.0
LSM2 7903.0
HNRNPL 7955.5
POLR2E 8049.0
HNRNPD 8054.0
DDX39B 8068.0
UPF1 8167.0
EFTUD2 8177.0


Influenza Viral RNA Transcription and Replication

Influenza Viral RNA Transcription and Replication
547
set Influenza Viral RNA Transcription and Replication
setSize 103
pANOVA 4.97e-08
s.dist -0.311
p.adjustANOVA 2.91e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282
RPS16 -8246
RPS17 -8231
RPS3A -7929
RPS28 -7809
RPL29 -7770
RPS21 -7764
RPS5 -7648
RPS27A -7640
RPS15 -7548
POLR2D -7461
RANBP2 -7410
RPS11 -7379
RPS14 -7325
RPL38 -7298
RPL13A -7282
NUP214 -7243
NUP205 -7210
RPL24 -7065
RPL32 -7023

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
POLR2D -7461.0
RANBP2 -7410.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
NUP214 -7243.0
NUP205 -7210.0
RPL24 -7065.0
RPL32 -7023.0
RPL6 -6916.0
RPS10 -6822.5
NUP43 -6740.0
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
RPL36 -6366.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
RPL35 -5900.0
RPS23 -5865.0
RPL5 -5749.0
NUP160 -5641.0
RPS19 -5609.0
SEC13 -5544.0
RPL37A -5473.0
NUP42 -5168.0
RPL19 -5108.0
NUP54 -4913.0
FAU -4829.0
POLR2C -4681.0
NUP107 -4634.0
NUP35 -4632.0
RPL35A -4460.0
RPL13 -4424.0
RPS6 -4373.0
POLR2G -4208.0
RPSA -4027.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
GTF2F2 -3055.0
NUP88 -2879.0
RPL7 -2750.0
RPL8 -2587.0
RPS18 -2478.0
POLR2L -2471.0
POLR2I -2271.0
DNAJC3 -2019.0
PARP1 -1776.0
RPL23A -1088.0
POLR2H -1058.0
POLR2F -932.0
NUP210 -565.0
RPL31 -303.0
RAE1 -259.0
RPS2 -219.0
NUP37 424.0
RPS27L 522.0
RPL27 706.0
NUP188 957.0
RPL7A 1400.0
NUP62 1422.0
TPR 1935.0
NUP153 2394.0
POLR2B 2513.0
RPL37 2677.0
NUP85 2708.0
GTF2F1 2709.0
RPS9 3031.0
RPS3 3136.0
AAAS 3172.0
POM121 3523.5
POM121C 3523.5
RPL3L 4494.0
NUP93 4512.0
NUP98 4522.0
RPL22 5158.0
NUP133 5700.0
NUP58 5787.0
NDC1 5827.0
IPO5 5863.0
NUP50 6188.0
POLR2A 6384.0
NUP155 6749.0
GRSF1 7696.0
POLR2E 8049.0


Formation of the ternary complex, and subsequently, the 43S complex

Formation of the ternary complex, and subsequently, the 43S complex
420
set Formation of the ternary complex, and subsequently, the 43S complex
setSize 42
pANOVA 4.75e-07
s.dist -0.449
p.adjustANOVA 2.67e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
EIF2S1 -7018.0
RPS10 -6822.5
RPS26 -6692.0
RPS8 -6597.0
EIF2S2 -6402.0
RPS4X -6019.0
EIF3M -5875.0
RPS23 -5865.0
EIF2S3 -5766.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
EIF2S1 -7018.0
RPS10 -6822.5
RPS26 -6692.0
RPS8 -6597.0
EIF2S2 -6402.0
RPS4X -6019.0
EIF3M -5875.0
RPS23 -5865.0
EIF2S3 -5766.5
RPS19 -5609.0
EIF3K -5288.0
FAU -4829.0
RPS6 -4373.0
RPSA -4027.0
RPS13 -3718.0
EIF3H -2613.0
RPS18 -2478.0
EIF3E -1890.0
EIF3G -1499.0
EIF3J -866.0
RPS2 -219.0
EIF3B -78.0
EIF3A -12.0
RPS27L 522.0
EIF3C 1656.5
EIF3D 2550.0
EIF3L 2985.0
RPS9 3031.0
RPS3 3136.0
EIF1AX 3460.0
EIF3F 5628.0


Influenza Infection

Influenza Infection
546
set Influenza Infection
setSize 120
pANOVA 6.95e-07
s.dist -0.262
p.adjustANOVA 3.75e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282
RPS16 -8246
RPS17 -8231
RPS3A -7929
RPS28 -7809
RPL29 -7770
RPS21 -7764
RPS5 -7648
RPS27A -7640
RPS15 -7548
POLR2D -7461
RANBP2 -7410
RPS11 -7379
RPS14 -7325
RPL38 -7298
RPL13A -7282
NUP214 -7243
NUP205 -7210
RPL24 -7065
RPL32 -7023

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
POLR2D -7461.0
RANBP2 -7410.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
NUP214 -7243.0
NUP205 -7210.0
RPL24 -7065.0
RPL32 -7023.0
RPL6 -6916.0
RPS10 -6822.5
NUP43 -6740.0
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
RPL36 -6366.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
RPL35 -5900.0
RPS23 -5865.0
RPL5 -5749.0
NUP160 -5641.0
RPS19 -5609.0
SEC13 -5544.0
RPL37A -5473.0
KPNA3 -5380.0
NUP42 -5168.0
RPL19 -5108.0
NUP54 -4913.0
FAU -4829.0
POLR2C -4681.0
NUP107 -4634.0
NUP35 -4632.0
RPL35A -4460.0
KPNA1 -4441.0
RPL13 -4424.0
RPS6 -4373.0
POLR2G -4208.0
RPSA -4027.0
KPNA2 -3986.0
RPL3 -3968.0
RPL10A -3822.0
KPNA5 -3761.0
RPS13 -3718.0
GTF2F2 -3055.0
NUP88 -2879.0
RPL7 -2750.0
RPL8 -2587.0
RPS18 -2478.0
POLR2L -2471.0
CPSF4 -2453.0
KPNA4 -2276.0
POLR2I -2271.0
DNAJC3 -2019.0
CLTC -1818.0
PARP1 -1776.0
RPL23A -1088.0
POLR2H -1058.0
CANX -1011.0
POLR2F -932.0
NUP210 -565.0
RPL31 -303.0
RAE1 -259.0
RPS2 -219.0
NUP37 424.0
RPS27L 522.0
RPL27 706.0
NUP188 957.0
RPL7A 1400.0
NUP62 1422.0
PABPN1 1437.5
CALR 1483.0
KPNA7 1735.5
TPR 1935.0
XPO1 2059.0
HSPA1A 2373.5
NUP153 2394.0
POLR2B 2513.0
RPL37 2677.0
NUP85 2708.0
GTF2F1 2709.0
RPS9 3031.0
RPS3 3136.0
AAAS 3172.0
EIF2AK2 3497.0
POM121 3523.5
POM121C 3523.5
TGFB1 3695.0
RPL3L 4494.0
NUP93 4512.0
NUP98 4522.0
RPL22 5158.0
KPNB1 5247.0
NUP133 5700.0
NUP58 5787.0
NDC1 5827.0
IPO5 5863.0
NUP50 6188.0
POLR2A 6384.0
NUP155 6749.0
CLTA 7341.0
GRSF1 7696.0
POLR2E 8049.0


Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
1038
set Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
setSize 102
pANOVA 7.85e-07
s.dist 0.283
p.adjustANOVA 4.08e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
NDUFA10 7483
NDUFA8 7131
NDUFA12 7130
MT-CYB 7011
NDUFAB1 6996
ECSIT 6963
UQCRC1 6960
SLC25A27 6807
NDUFV1 6489
ATP5F1B 6480
ACAD9 6453
COX5B 6442
NDUFA9 6209
ATP5F1D 6163
MT-CO1 6162
TRAP1 6126
SDHC 6123
NDUFB10 6086
COX5A 6026
COX4I1 6009

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NDUFA10 7483.0
NDUFA8 7131.0
NDUFA12 7130.0
MT-CYB 7011.0
NDUFAB1 6996.0
ECSIT 6963.0
UQCRC1 6960.0
SLC25A27 6807.0
NDUFV1 6489.0
ATP5F1B 6480.0
ACAD9 6453.0
COX5B 6442.0
NDUFA9 6209.0
ATP5F1D 6163.0
MT-CO1 6162.0
TRAP1 6126.0
SDHC 6123.0
NDUFB10 6086.0
COX5A 6026.0
COX4I1 6009.0
COX18 5890.0
ETFB 5756.0
SDHB 5629.0
NDUFS5 5612.0
ATP5MC3 5582.0
MT-ND1 5579.0
NDUFB7 5573.0
NDUFV3 5524.0
MT-ATP8 5500.0
NDUFAF7 5479.0
ETFDH 5372.0
COQ10A 5345.0
ETFA 5269.0
NDUFB6 4983.0
MT-ND5 4937.0
CYC1 4883.0
MT-ND2 4879.0
TIMMDC1 4862.0
MT-ND6 4767.0
MT-ATP6 4629.0
MT-ND4 4382.0
NDUFS3 4380.0
COX11 4280.0
TACO1 4096.0
NDUFB11 4068.0
DMAC2L 4044.0
MT-CO2 3989.0
ATP5ME 3979.0
NDUFAF3 3956.0
MT-CO3 3879.0
NDUFS1 3819.0
UCP2 3761.0
SLC25A14 3669.0
COX6B1 3551.0
NDUFS8 3493.0
COX7A2L 3473.0
ATP5PD 3350.0
UQCRC2 3202.0
SDHA 3123.5
NDUFS7 3090.0
UQCRFS1 3065.0
ATP5PO 2966.5
NDUFB4 2890.0
NDUFAF6 2862.0
COX6A1 2441.0
NDUFA4 2427.0
NDUFA6 2222.0
NDUFS4 2132.0
SCO1 1481.0
UCP1 1390.0
NDUFAF4 1307.0
NDUFAF1 1191.0
NDUFB8 1015.5
NDUFA13 544.0
SDHD -389.5
NDUFA3 -953.0
ATP5PF -1203.0
UCP3 -1769.0
ATP5MF -1892.0
NDUFB5 -1930.0
NDUFV2 -2183.0
COX7B -2241.0
NDUFC2 -3052.5
MT-ND3 -3112.0
UQCR11 -3215.5
NDUFA11 -3345.5
NUBPL -3355.0
NDUFA2 -3380.0
NDUFS2 -3401.0
COX7C -3618.0
UQCR10 -3998.0
COQ10B -4282.0
NDUFAF5 -4827.0
UQCRB -5007.0
UQCRH -5150.5
TMEM126B -5318.0
ATP5MG -5696.5
COX16 -6527.0
NDUFB3 -6948.0
COX19 -7585.0
PM20D1 -7706.0
ATP5F1E -8086.0


Mitochondrial Fatty Acid Beta-Oxidation

Mitochondrial Fatty Acid Beta-Oxidation
685
set Mitochondrial Fatty Acid Beta-Oxidation
setSize 34
pANOVA 9.41e-07
s.dist 0.486
p.adjustANOVA 4.72e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
ACOT7 7952.0
ACAA2 7671.0
PCCA 7601.0
ACOT1 7508.5
ACOT2 7508.5
HADHB 7290.0
MECR 7210.0
ACOT13 7051.0
ACADVL 7006.0
NDUFAB1 6996.0
THEM4 6916.0
ECI1 6811.0
MCEE 6734.0
ACOT11 6541.0
MMAA 6426.0
HADHA 6375.0
ACADM 5984.0
ACADL 5978.0
HADH 5813.0
ACADS 4701.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ACOT7 7952.0
ACAA2 7671.0
PCCA 7601.0
ACOT1 7508.5
ACOT2 7508.5
HADHB 7290.0
MECR 7210.0
ACOT13 7051.0
ACADVL 7006.0
NDUFAB1 6996.0
THEM4 6916.0
ECI1 6811.0
MCEE 6734.0
ACOT11 6541.0
MMAA 6426.0
HADHA 6375.0
ACADM 5984.0
ACADL 5978.0
HADH 5813.0
ACADS 4701.0
ACSF2 4566.0
PCCB 4518.0
MCAT 4486.0
MMUT 2827.0
DECR1 1813.0
THEM5 765.0
ACAD10 -476.0
ACBD6 -500.0
ACOT12 -1585.0
DBI -2008.0
ACAD11 -2890.0
ACSM3 -2985.0
ACOT9 -5006.0
PCTP -5715.0


Selenoamino acid metabolism

Selenoamino acid metabolism
1092
set Selenoamino acid metabolism
setSize 84
pANOVA 1.09e-06
s.dist -0.308
p.adjustANOVA 5.17e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
NNMT -6950.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
RPL24 -7065.0
RPL32 -7023.0
NNMT -6950.0
RPL6 -6916.0
RPS10 -6822.5
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
SEPSECS -6470.0
RPL36 -6366.0
RPLP2 -6273.0
RPL23 -6194.0
RPL30 -6152.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
RPL35 -5900.0
RPS23 -5865.0
RPL5 -5749.0
RPS19 -5609.0
RPL37A -5473.0
RPL19 -5108.0
FAU -4829.0
EEFSEC -4655.0
MAT1A -4559.0
RPL35A -4460.0
RPL13 -4424.0
DARS1 -4385.0
RPS6 -4373.0
SCLY -4215.0
SECISBP2 -4050.0
RPSA -4027.0
RPL3 -3968.0
RPL10A -3822.0
RPS13 -3718.0
RPL7 -2750.0
RPL8 -2587.0
RPS18 -2478.0
RARS1 -2400.0
LARS1 -2263.0
RPL23A -1088.0
INMT -1055.5
AIMP1 -487.0
RPL31 -303.0
RPS2 -219.0
RPS27L 522.0
GNMT 585.0
RPL27 706.0
RPL7A 1400.0
RPL37 2677.0
EPRS1 2820.0
RPS9 3031.0
RPS3 3136.0
RPL3L 4494.0
IARS1 4606.0
AHCY 4901.0
RPL22 5158.0
MARS1 6293.0
KARS1 6365.0
CBS 6623.5
CTH 7025.0
AIMP2 7324.0
PSTK 7348.0
SARS1 7350.0
PAPSS2 7656.0
GSR 7801.0
TXNRD1 7917.0
PAPSS1 8121.0


Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
539
set Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
setSize 106
pANOVA 1.11e-06
s.dist -0.274
p.adjustANOVA 5.17e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
FCGR2B -8284.0
CD300C -8175.0
CD300LF -8159.0
CD22 -8146.0
LILRA1 -8064.5
LILRA2 -8064.5
LILRB1 -8064.5
LILRB2 -8064.5
CLEC2D -8029.0
SIGLEC1 -7792.0
CD200R1 -7467.5
CD300A -7398.5
CD300LD -7398.5
TREML2 -7173.0
FCGR1A -7140.5
PVR -7125.0
ITGA4 -7054.0
CD33 -6719.5
SIGLEC6 -6719.5
TRBC1 -6620.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FCGR2B -8284.0
CD300C -8175.0
CD300LF -8159.0
CD22 -8146.0
LILRA1 -8064.5
LILRA2 -8064.5
LILRB1 -8064.5
LILRB2 -8064.5
CLEC2D -8029.0
SIGLEC1 -7792.0
CD200R1 -7467.5
CD300A -7398.5
CD300LD -7398.5
TREML2 -7173.0
FCGR1A -7140.5
PVR -7125.0
ITGA4 -7054.0
CD33 -6719.5
SIGLEC6 -6719.5
TRBC1 -6620.5
HCST -6444.0
TYROBP -6404.0
LAIR1 -6386.0
ITGB7 -6367.0
SIGLEC12 -6057.5
SIGLEC7 -6057.5
SIGLEC8 -6057.5
SIGLEC9 -6057.5
CRTAM -5937.0
CD247 -5933.0
ICAM5 -5517.0
COLEC12 -5439.0
TREM1 -5414.0
CD1D -5308.0
PIANP -5292.0
SLAMF7 -5287.0
TREM2 -5197.0
KLRC1 -5053.5
CD81 -4889.0
CD3E -4862.0
TREML4 -3987.0
RAET1E -3907.5
CD3D -3905.0
SIGLEC10 -3863.5
SIGLEC11 -3863.5
CD8A -3675.0
MADCAM1 -3488.0
KIR2DL1 -3436.0
KIR2DL3 -3436.0
KIR2DL4 -3436.0
KIR3DL1 -3436.0
KIR3DL2 -3436.0
CD3G -3199.0
CD8B -3184.5
KLRK1 -3000.0
CD34 -2848.0
SLAMF6 -2843.0
KLRB1 -2512.0
KLRD1 -2105.0
IGKV1-12 -1796.5
IGKV1-16 -1796.5
IGKV1-17 -1796.5
IGKV1-39 -1796.5
IGKV1-5 -1796.5
IGKV1D-12 -1796.5
IGKV1D-16 -1796.5
IGKV1D-39 -1796.5
IFITM1 -1331.0
IGLV6-57 -1290.0
ITGB2 -1161.0
SELL -825.0
ICAM4 -501.0
IGHV4-34 -409.5
IGHV4-39 -409.5
IGHV4-59 -409.5
CD300E 245.0
OSCAR 529.0
HLA-A 538.5
HLA-B 538.5
HLA-C 538.5
HLA-E 538.5
HLA-F 538.5
HLA-G 538.5
ICAM1 971.0
TREML1 1797.0
CD40LG 1866.0
B2M 2072.0
NECTIN2 2095.0
ITGAL 2183.0
NCR3 2749.0
IGKC 2909.0
CD226 3085.0
CDH1 3439.0
CXADR 3737.0
CD40 4249.0
ITGB1 4674.0
ICAM2 4707.0
KLRG1 4769.0
CLEC4G 5542.0
C3 6951.0
CD19 7249.0
CD300LG 7303.0
VCAM1 7321.0
CD96 7332.0
FCGR3A 7385.5
CD200 7711.0


Fatty acid metabolism

Fatty acid metabolism
400
set Fatty acid metabolism
setSize 160
pANOVA 1.41e-06
s.dist 0.221
p.adjustANOVA 6.4e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
PPT2 8132.5
NUDT7 8063.0
ACOT7 7952.0
ACSL6 7907.5
GGT5 7852.0
SLC27A2 7786.0
ACSL1 7784.0
HSD17B8 7780.0
CYP1B1 7721.0
HAO2 7672.0
ACAA2 7671.0
ACOX2 7644.0
PCCA 7601.0
ACOT1 7508.5
ACOT2 7508.5
HSD17B4 7497.0
CRAT 7368.0
HADHB 7290.0
PPARD 7270.0
ACOX1 7255.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PPT2 8132.5
NUDT7 8063.0
ACOT7 7952.0
ACSL6 7907.5
GGT5 7852.0
SLC27A2 7786.0
ACSL1 7784.0
HSD17B8 7780.0
CYP1B1 7721.0
HAO2 7672.0
ACAA2 7671.0
ACOX2 7644.0
PCCA 7601.0
ACOT1 7508.5
ACOT2 7508.5
HSD17B4 7497.0
CRAT 7368.0
HADHB 7290.0
PPARD 7270.0
ACOX1 7255.0
PTGES2 7214.0
MECR 7210.0
CYP4A11 7182.5
CYP4A22 7182.5
CYP4F11 7182.5
ACSF3 7053.0
ACOT13 7051.0
PTGR2 7049.5
PHYH 7045.0
ACADVL 7006.0
NDUFAB1 6996.0
ALDH3A2 6988.0
ELOVL1 6929.0
THEM4 6916.0
ECI1 6811.0
AMACR 6750.0
MCEE 6734.0
CYP4F2 6710.0
ACOT11 6541.0
CPT1B 6451.0
SLC25A20 6449.0
ABCD1 6427.0
MMAA 6426.0
HADHA 6375.0
ALOX12 6295.0
MAPKAPK2 6139.0
ACAA1 6125.0
SCD 6085.0
EHHADH 6024.0
ACADM 5984.0
ACADL 5978.0
HADH 5813.0
HSD17B3 5727.0
ELOVL5 5710.0
EPHX2 5626.0
CPT2 5615.0
NUDT19 5464.0
DPEP3 5463.0
ABCC1 5260.0
CPT1A 5252.0
PON2 5161.0
LTA4H 4990.0
ACOT6 4818.0
MLYCD 4748.0
PON1 4745.0
ACADS 4701.0
ACSF2 4566.0
PCCB 4518.0
MCAT 4486.0
ELOVL2 4317.0
MORC2 4155.0
ACBD5 4146.0
ELOVL3 4059.0
PTGR1 3940.0
ACLY 3933.0
CYP2U1 3661.0
GGT1 3624.0
ALOXE3 3570.0
ELOVL7 3264.0
ACOT8 3216.0
GPX2 3181.0
CYP4B1 3008.0
PTGS1 2945.0
ELOVL6 2936.0
MMUT 2827.0
PTGIS 2632.0
HACL1 2573.0
CYP8B1 2544.0
ACSL5 2484.0
ACOX3 2479.0
ACOXL 2122.0
CYP1A2 1984.0
DECR1 1813.0
PECR 1557.0
PTGDS 1364.5
CYP4F22 1324.0
TECR 1244.0
HACD3 849.0
THEM5 765.0
CBR1 743.0
ALOX12B 627.0
ELOVL4 485.0
MID1IP1 349.0
HACD4 7.0
PRKAA2 -151.0
ACBD4 -269.0
ACAD10 -476.0
TECRL -489.0
FAAH -494.0
ACBD6 -500.0
GPX1 -981.0
OLAH -1201.0
ACOT12 -1585.0
RXRA -1980.0
DBI -2008.0
DPEP1 -2058.0
ACSBG2 -2092.0
CYP1A1 -2131.0
ALOX15B -2390.0
FADS2 -2411.0
ACOT4 -2617.0
ACAD11 -2890.0
ACSM3 -2985.0
PTGS2 -3418.0
PPT1 -3753.0
PON3 -3794.0
FADS1 -4018.0
ALOX15 -4198.0
PLA2G4A -4306.0
HACD2 -4442.0
ACSL4 -4736.0
ACOT9 -5006.0
CBR4 -5009.0
FASN -5133.0
DPEP2 -5556.0
SLC25A17 -5644.0
SLC27A3 -5657.0
PCTP -5715.0
THRSP -6068.0
LTC4S -6307.0
ECI2 -6476.0
HPGD -6516.0
SLC25A1 -6520.0
HACD1 -6539.0
TBXAS1 -6596.0
PTGES3 -6729.0
ACSL3 -6761.0
PRKAG2 -6923.0
HPGDS -6927.0
CYP4F8 -7313.0
ACSBG1 -7512.0
ALOX5AP -7609.0
PRKAB2 -7660.0
CYP2J2 -7731.0
CYP4F3 -7751.0
HSD17B12 -7912.0
ACACA -7955.0
ALOX5 -8075.0
CROT -8187.0
GPX4 -8221.0


Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S

Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
52
set Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
setSize 48
pANOVA 2.23e-06
s.dist -0.395
p.adjustANOVA 9.77e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
EIF2S1 -7018.0
RPS10 -6822.5
RPS26 -6692.0
RPS8 -6597.0
EIF4EBP1 -6482.0
EIF2S2 -6402.0
RPS4X -6019.0
EIF4A2 -5979.0
EIF3M -5875.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
EIF2S1 -7018.0
RPS10 -6822.5
RPS26 -6692.0
RPS8 -6597.0
EIF4EBP1 -6482.0
EIF2S2 -6402.0
RPS4X -6019.0
EIF4A2 -5979.0
EIF3M -5875.0
RPS23 -5865.0
EIF2S3 -5766.5
RPS19 -5609.0
EIF3K -5288.0
FAU -4829.0
RPS6 -4373.0
RPSA -4027.0
RPS13 -3718.0
EIF3H -2613.0
RPS18 -2478.0
EIF3E -1890.0
EIF3G -1499.0
EIF3J -866.0
RPS2 -219.0
EIF4A1 -181.0
EIF3B -78.0
EIF4E -29.0
EIF3A -12.0
RPS27L 522.0
EIF3C 1656.5
EIF3D 2550.0
EIF3L 2985.0
RPS9 3031.0
RPS3 3136.0
EIF1AX 3460.0
EIF4G1 4151.0
EIF3F 5628.0
EIF4H 7514.0


Citric acid cycle (TCA cycle)

Citric acid cycle (TCA cycle)
191
set Citric acid cycle (TCA cycle)
setSize 22
pANOVA 2.43e-06
s.dist 0.58
p.adjustANOVA 0.000103



Top enriched genes

Top 20 genes
GeneID Gene Rank
OGDH 8010.0
ACO2 7469.0
CS 7355.0
ME3 7099.0
DLST 7073.0
FAHD1 6902.0
NNT 6791.0
IDH3G 6298.0
SDHC 6123.0
IDH2 6021.0
SDHB 5629.0
MDH2 5314.0
IDH3A 4957.0
IDH3B 4913.0
FH 4639.0
SUCLG1 3584.0
SDHA 3123.5
DLD 3101.0
SUCLG2 1833.0
SUCLA2 608.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OGDH 8010.0
ACO2 7469.0
CS 7355.0
ME3 7099.0
DLST 7073.0
FAHD1 6902.0
NNT 6791.0
IDH3G 6298.0
SDHC 6123.0
IDH2 6021.0
SDHB 5629.0
MDH2 5314.0
IDH3A 4957.0
IDH3B 4913.0
FH 4639.0
SUCLG1 3584.0
SDHA 3123.5
DLD 3101.0
SUCLG2 1833.0
SUCLA2 608.0
SDHD -389.5
ME2 -2641.0


Respiratory electron transport

Respiratory electron transport
1037
set Respiratory electron transport
setSize 83
pANOVA 2.51e-06
s.dist 0.299
p.adjustANOVA 0.000104



Top enriched genes

Top 20 genes
GeneID Gene Rank
NDUFA10 7483
NDUFA8 7131
NDUFA12 7130
MT-CYB 7011
NDUFAB1 6996
ECSIT 6963
UQCRC1 6960
NDUFV1 6489
ACAD9 6453
COX5B 6442
NDUFA9 6209
MT-CO1 6162
TRAP1 6126
SDHC 6123
NDUFB10 6086
COX5A 6026
COX4I1 6009
COX18 5890
ETFB 5756
SDHB 5629

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NDUFA10 7483.0
NDUFA8 7131.0
NDUFA12 7130.0
MT-CYB 7011.0
NDUFAB1 6996.0
ECSIT 6963.0
UQCRC1 6960.0
NDUFV1 6489.0
ACAD9 6453.0
COX5B 6442.0
NDUFA9 6209.0
MT-CO1 6162.0
TRAP1 6126.0
SDHC 6123.0
NDUFB10 6086.0
COX5A 6026.0
COX4I1 6009.0
COX18 5890.0
ETFB 5756.0
SDHB 5629.0
NDUFS5 5612.0
MT-ND1 5579.0
NDUFB7 5573.0
NDUFV3 5524.0
NDUFAF7 5479.0
ETFDH 5372.0
COQ10A 5345.0
ETFA 5269.0
NDUFB6 4983.0
MT-ND5 4937.0
CYC1 4883.0
MT-ND2 4879.0
TIMMDC1 4862.0
MT-ND6 4767.0
MT-ND4 4382.0
NDUFS3 4380.0
COX11 4280.0
TACO1 4096.0
NDUFB11 4068.0
MT-CO2 3989.0
NDUFAF3 3956.0
MT-CO3 3879.0
NDUFS1 3819.0
COX6B1 3551.0
NDUFS8 3493.0
COX7A2L 3473.0
UQCRC2 3202.0
SDHA 3123.5
NDUFS7 3090.0
UQCRFS1 3065.0
NDUFB4 2890.0
NDUFAF6 2862.0
COX6A1 2441.0
NDUFA4 2427.0
NDUFA6 2222.0
NDUFS4 2132.0
SCO1 1481.0
NDUFAF4 1307.0
NDUFAF1 1191.0
NDUFB8 1015.5
NDUFA13 544.0
SDHD -389.5
NDUFA3 -953.0
NDUFB5 -1930.0
NDUFV2 -2183.0
COX7B -2241.0
NDUFC2 -3052.5
MT-ND3 -3112.0
UQCR11 -3215.5
NDUFA11 -3345.5
NUBPL -3355.0
NDUFA2 -3380.0
NDUFS2 -3401.0
COX7C -3618.0
UQCR10 -3998.0
COQ10B -4282.0
NDUFAF5 -4827.0
UQCRB -5007.0
UQCRH -5150.5
TMEM126B -5318.0
COX16 -6527.0
NDUFB3 -6948.0
COX19 -7585.0


Signaling by ROBO receptors

Signaling by ROBO receptors
1163
set Signaling by ROBO receptors
setSize 178
pANOVA 2.76e-06
s.dist -0.204
p.adjustANOVA 0.00011



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282
RPS16 -8246
RPS17 -8231
ELOC -8174
ROBO2 -8163
UPF2 -8156
RPS3A -7929
RPS28 -7809
RPL29 -7770
RPS21 -7764
PAK3 -7738
RPS5 -7648
RPS27A -7640
PAK1 -7605
PAK4 -7549
RPS15 -7548
PSMA4 -7394
RPS11 -7379
VASP -7374
RPS14 -7325

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
ELOC -8174.0
ROBO2 -8163.0
UPF2 -8156.0
RPS3A -7929.0
RPS28 -7809.0
RPL29 -7770.0
RPS21 -7764.0
PAK3 -7738.0
RPS5 -7648.0
RPS27A -7640.0
PAK1 -7605.0
PAK4 -7549.0
RPS15 -7548.0
PSMA4 -7394.0
RPS11 -7379.0
VASP -7374.0
RPS14 -7325.0
RPL38 -7298.0
RPL13A -7282.0
PSMA6 -7250.0
SRC -7166.0
PRKCA -7092.0
RPL24 -7065.0
RPL32 -7023.0
PRKAR2A -7003.0
PSMB6 -6996.0
RPL6 -6916.0
RPS10 -6822.5
PPP3CB -6779.0
RPS26 -6692.0
RPL18 -6689.0
RPL18A -6679.0
RPLP1 -6661.0
RPS8 -6597.0
PSMC5 -6575.0
RPL36 -6366.0
PRKACB -6340.0
RPLP2 -6273.0
PSMB7 -6252.0
RPL23 -6194.0
CDC42 -6175.0
RPL30 -6152.0
PAK2 -6088.0
RPL15 -6030.0
RPS4X -6019.0
RPL28 -5981.0
PSMB1 -5931.0
RPL35 -5900.0
RPS23 -5865.0
SRGAP3 -5850.0
RPL5 -5749.0
RPS19 -5609.0
PSMB4 -5607.0
RPL37A -5473.0
PSMD5 -5412.0
RPL19 -5108.0
PSMA3 -5078.0
PSMA2 -5050.5
SRGAP2 -4905.0
FAU -4829.0
PAK5 -4805.0
FLRT3 -4708.0
GSPT2 -4504.0
RPL35A -4460.0
RPL13 -4424.0
NCK2 -4387.0
UPF3A -4384.0
RPS6 -4373.0
COL4A5 -4372.0
ETF1 -4323.0
MAGOH -4309.0
PSMD14 -4055.0
RPSA -4027.0
RPL3 -3968.0
ISL1 -3924.0
PSMD8 -3851.0
RPL10A -3822.0
RPS13 -3718.0
PSMB3 -3665.0
LHX2 -3561.0
PSMC2 -3419.0
PSMD6 -3353.0
RBX1 -3219.0
NCBP1 -3144.0
PSMD4 -3118.0
PSMC4 -3007.0
RPL7 -2750.0
RPL8 -2587.0
PSMA7 -2576.0
RBM8A -2564.0
RPS18 -2478.0
PSMA1 -2388.0
PSMD2 -2319.0
PSMD1 -2102.0
ROBO1 -1904.0
PSMA8 -1679.0
PSMC6 -1541.0
SOS1 -1475.0
LHX4 -1469.0
PSMD11 -1181.0
PSMD3 -1168.0
RPL23A -1088.0
PSMA5 -604.0
CUL2 -316.0
RPL31 -303.0
ZSWIM8 -287.0
RPS2 -219.0
PSMB5 -153.0
PSMD7 321.0
ROBO3 480.0
RPS27L 522.0
LHX3 607.0
RPL27 706.0
RNPS1 803.0
NCBP2 898.0
SOS2 945.0
EIF4A3 950.0
UBC 1013.0
PSMC1 1107.0
RPL7A 1400.0
DCC 1508.0
PSME4 1510.0
PSMB2 1548.0
MAGOHB 1608.0
CAP2 1689.0
UPF3B 2124.0
PSME2 2230.0
PSMC3 2256.0
CASC3 2399.0
EVL 2510.0
RPL37 2677.0
DAG1 2723.0
GPC1 2787.0
PFN1 2795.0
AKAP5 2803.0
PAK6 2950.0
SRGAP1 3023.0
RPS9 3031.0
RPS3 3136.0
HOXA2 3282.0
MYO9B 3440.0
USP33 3752.0
CAP1 3974.0
ABL1 3993.0
RHOA 4069.0
PSMD12 4108.0
EIF4G1 4151.0
NTN1 4195.0
LHX9 4232.0
ENAH 4245.0
RPL3L 4494.0
PSMD13 4498.0
PRKACA 4516.0
ARHGAP39 4521.0
SLIT3 4902.0
NELL2 4955.0
ABL2 5010.0
PSMB9 5019.0
RPL22 5158.0
SLIT1 5988.0
LDB1 5989.0
PSMF1 6184.0
GSPT1 6438.0
MSI1 6507.0
PSME1 6608.0
CLASP2 6800.0
CXCL12 6840.0
NCK1 7272.0
CXCR4 7462.0
PSMB8 7523.0
SLIT2 7657.0
RAC1 7746.0
NRP1 7939.0
PFN2 7986.0
CLASP1 8148.0


Ribosomal scanning and start codon recognition

Ribosomal scanning and start codon recognition
1049
set Ribosomal scanning and start codon recognition
setSize 48
pANOVA 2.82e-06
s.dist -0.391
p.adjustANOVA 0.00011



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
EIF2S1 -7018.0
RPS10 -6822.5
RPS26 -6692.0
RPS8 -6597.0
EIF2S2 -6402.0
RPS4X -6019.0
EIF4A2 -5979.0
EIF3M -5875.0
RPS23 -5865.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
EIF2S1 -7018.0
RPS10 -6822.5
RPS26 -6692.0
RPS8 -6597.0
EIF2S2 -6402.0
RPS4X -6019.0
EIF4A2 -5979.0
EIF3M -5875.0
RPS23 -5865.0
EIF2S3 -5766.5
RPS19 -5609.0
EIF3K -5288.0
EIF5 -4910.0
FAU -4829.0
RPS6 -4373.0
RPSA -4027.0
RPS13 -3718.0
EIF3H -2613.0
RPS18 -2478.0
EIF3E -1890.0
EIF3G -1499.0
EIF3J -866.0
RPS2 -219.0
EIF4A1 -181.0
EIF3B -78.0
EIF4E -29.0
EIF3A -12.0
RPS27L 522.0
EIF3C 1656.5
EIF3D 2550.0
EIF3L 2985.0
RPS9 3031.0
RPS3 3136.0
EIF1AX 3460.0
EIF4G1 4151.0
EIF3F 5628.0
EIF4H 7514.0


Pyruvate metabolism and Citric Acid (TCA) cycle

Pyruvate metabolism and Citric Acid (TCA) cycle
906
set Pyruvate metabolism and Citric Acid (TCA) cycle
setSize 52
pANOVA 4.4e-06
s.dist 0.368
p.adjustANOVA 0.000167



Top enriched genes

Top 20 genes
GeneID Gene Rank
OGDH 8010.0
LDHC 7609.0
BSG 7570.0
PDHX 7471.0
ACO2 7469.0
PDHB 7468.0
CS 7355.0
DLAT 7320.0
PPARD 7270.0
ME3 7099.0
DLST 7073.0
HAGH 6949.0
FAHD1 6902.0
L2HGDH 6828.0
NNT 6791.0
D2HGDH 6672.0
IDH3G 6298.0
LDHB 6149.5
SDHC 6123.0
IDH2 6021.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OGDH 8010.0
LDHC 7609.0
BSG 7570.0
PDHX 7471.0
ACO2 7469.0
PDHB 7468.0
CS 7355.0
DLAT 7320.0
PPARD 7270.0
ME3 7099.0
DLST 7073.0
HAGH 6949.0
FAHD1 6902.0
L2HGDH 6828.0
NNT 6791.0
D2HGDH 6672.0
IDH3G 6298.0
LDHB 6149.5
SDHC 6123.0
IDH2 6021.0
SDHB 5629.0
MDH2 5314.0
PDPR 5035.0
IDH3A 4957.0
IDH3B 4913.0
FH 4639.0
MPC2 4435.0
PDHA1 4337.0
PDK4 4094.0
VDAC1 3653.0
SUCLG1 3584.0
PDK2 3361.0
SDHA 3123.5
DLD 3101.0
SLC16A1 3094.0
PDP2 2951.0
PDK1 2031.0
SUCLG2 1833.0
SUCLA2 608.0
MPC1 407.0
SDHD -389.5
PDK3 -549.0
RXRA -1980.0
ME2 -2641.0
ADHFE1 -4312.0
SLC16A8 -5046.0
PDP1 -5939.0
SLC16A3 -6714.0
GLO1 -7083.0
GSTZ1 -7293.0
LDHA -7395.0
ME1 -7972.0


Translation initiation complex formation

Translation initiation complex formation
1306
set Translation initiation complex formation
setSize 47
pANOVA 4.56e-06
s.dist -0.387
p.adjustANOVA 0.000168



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
EIF2S1 -7018.0
RPS10 -6822.5
RPS26 -6692.0
RPS8 -6597.0
EIF2S2 -6402.0
RPS4X -6019.0
EIF4A2 -5979.0
EIF3M -5875.0
RPS23 -5865.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -8282.0
RPS16 -8246.0
RPS17 -8231.0
RPS3A -7929.0
RPS28 -7809.0
RPS21 -7764.0
RPS5 -7648.0
RPS27A -7640.0
RPS15 -7548.0
RPS11 -7379.0
RPS14 -7325.0
EIF2S1 -7018.0
RPS10 -6822.5
RPS26 -6692.0
RPS8 -6597.0
EIF2S2 -6402.0
RPS4X -6019.0
EIF4A2 -5979.0
EIF3M -5875.0
RPS23 -5865.0
EIF2S3 -5766.5
RPS19 -5609.0
EIF3K -5288.0
FAU -4829.0
RPS6 -4373.0
RPSA -4027.0
RPS13 -3718.0
EIF3H -2613.0
RPS18 -2478.0
EIF3E -1890.0
EIF3G -1499.0
EIF3J -866.0
RPS2 -219.0
EIF4A1 -181.0
EIF3B -78.0
EIF4E -29.0
EIF3A -12.0
RPS27L 522.0
EIF3C 1656.5
EIF3D 2550.0
EIF3L 2985.0
RPS9 3031.0
RPS3 3136.0
EIF1AX 3460.0
EIF4G1 4151.0
EIF3F 5628.0
EIF4H 7514.0


Bile acid and bile salt metabolism

Bile acid and bile salt metabolism
113
set Bile acid and bile salt metabolism
setSize 37
pANOVA 1.16e-05
s.dist 0.417
p.adjustANOVA 0.000419



Top enriched genes

Top 20 genes
GeneID Gene Rank
SLCO1A2 7943
AKR1D1 7924
SLC27A2 7786
OSBPL1A 7651
ACOX2 7644
OSBPL9 7624
HSD17B4 7497
OSBPL6 7390
NCOA1 7218
SLCO1B1 7114
SLCO1B3 7114
SLC27A5 7037
AMACR 6750
ABCB11 6290
NR1H4 5883
BAAT 5784
OSBPL2 5717
NCOA2 5324
OSBPL3 4992
CYP7A1 4954

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SLCO1A2 7943.0
AKR1D1 7924.0
SLC27A2 7786.0
OSBPL1A 7651.0
ACOX2 7644.0
OSBPL9 7624.0
HSD17B4 7497.0
OSBPL6 7390.0
NCOA1 7218.0
SLCO1B1 7114.0
SLCO1B3 7114.0
SLC27A5 7037.0
AMACR 6750.0
ABCB11 6290.0
NR1H4 5883.0
BAAT 5784.0
OSBPL2 5717.0
NCOA2 5324.0
OSBPL3 4992.0
CYP7A1 4954.0
SLC10A1 4785.0
CYP27A1 4354.0
ALB 3808.0
ACOT8 3216.0
CYP46A1 2984.0
PTGIS 2632.0
OSBP 2607.0
CYP8B1 2544.0
STARD5 594.0
FABP6 393.5
RXRA -1980.0
HSD3B7 -2383.0
CYP39A1 -4425.0
CH25H -7050.0
OSBPL7 -7479.0
ABCC3 -7823.0
CYP7B1 -7839.0


Adaptive Immune System

Adaptive Immune System
59
set Adaptive Immune System
setSize 643
pANOVA 2.24e-05
s.dist -0.0985
p.adjustANOVA 0.000785



Top enriched genes

Top 20 genes
GeneID Gene Rank
PTPRC -8287.0
FCGR2B -8284.0
TRIP12 -8280.0
HLA-DQB1 -8259.5
HLA-DQB2 -8259.5
PTPN6 -8219.0
IGHM -8190.0
CD300C -8175.0
ELOC -8174.0
KLHL20 -8164.0
CD300LF -8159.0
SEC24A -8147.0
CD22 -8146.0
HLA-DRA -8140.0
CD86 -8127.0
DYNC1LI2 -8117.0
LILRA1 -8064.5
LILRA2 -8064.5
LILRB1 -8064.5
LILRB2 -8064.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PTPRC -8287.0
FCGR2B -8284.0
TRIP12 -8280.0
HLA-DQB1 -8259.5
HLA-DQB2 -8259.5
PTPN6 -8219.0
IGHM -8190.0
CD300C -8175.0
ELOC -8174.0
KLHL20 -8164.0
CD300LF -8159.0
SEC24A -8147.0
CD22 -8146.0
HLA-DRA -8140.0
CD86 -8127.0
DYNC1LI2 -8117.0
LILRA1 -8064.5
LILRA2 -8064.5
LILRB1 -8064.5
LILRB2 -8064.5
ASB12 -8049.0
CLEC2D -8029.0
PPIA -8021.5
UBE3C -7971.0
FBXW7 -7963.0
SEC61A2 -7949.0
KIF18A -7894.0
ASB9 -7893.0
CUL3 -7874.0
DCTN4 -7862.0
HECTD2 -7859.0
CD101 -7849.0
FBXL4 -7829.0
BTK -7804.0
SIGLEC1 -7792.0
PIK3AP1 -7781.0
HRAS -7755.0
PAK3 -7738.0
STX4 -7729.0
UBE2F -7727.5
SEC23A -7718.0
NEDD4 -7710.0
RASGRP3 -7692.0
YES1 -7678.0
WSB1 -7676.0
CD74 -7670.0
RPS27A -7640.0
PRKCB -7632.0
PAK1 -7605.0
LNX1 -7568.0
CD200R1 -7467.5
UBE2D3 -7462.0
RNF19B -7429.0
FBXW4 -7425.0
CUL1 -7405.0
CD300A -7398.5
CD300LD -7398.5
PSMA4 -7394.0
KLHL22 -7386.5
VASP -7374.0
RNF7 -7356.0
TIRAP -7316.0
DYNC1I2 -7307.0
RNF25 -7281.0
CUL7 -7264.0
PSMA6 -7250.0
TREML2 -7173.0
SRC -7166.0
FCGR1A -7140.5
FCGR1B -7140.5
PVR -7125.0
ANAPC10 -7079.0
ITGA4 -7054.0
PPP2R5A -7024.0
PSMB6 -6996.0
TAB2 -6989.0
CTSH -6980.0
PPP2R1B -6978.0
UBE2E2 -6976.0
TLR2 -6961.0
PJA1 -6959.0
WAS -6934.0
MRC1 -6930.0
DZIP3 -6887.0
FBXO4 -6846.0
SPSB1 -6841.0
MEX3C -6814.0
FBXO31 -6782.0
PPP3CB -6779.0
PPP2R5C -6762.0
UBE3A -6726.0
CD33 -6719.5
SIGLEC6 -6719.5
NFATC3 -6716.0
UBOX5 -6711.0
FBXO41 -6697.0
CTSK -6682.0
CALM1 -6675.0
HERC2 -6623.0
TRBC1 -6620.5
CAPZA2 -6618.0
RASGRP2 -6609.0
PSMC5 -6575.0
KIFAP3 -6571.0
SAR1B -6531.0
UBE2J1 -6515.0
PDCD1 -6489.0
PJA2 -6466.0
TRIM37 -6450.0
HCST -6444.0
PPP3R1 -6429.5
UBE3D -6412.0
ANAPC13 -6410.0
TYROBP -6404.0
MAP3K14 -6387.0
LAIR1 -6386.0
UBE2C -6382.0
ITGB7 -6367.0
UBAC1 -6357.0
ASB6 -6352.0
PRKACB -6340.0
BLMH -6322.0
PSMB7 -6252.0
KLHL3 -6220.0
KLHL42 -6206.0
CDC42 -6175.0
CBLB -6160.0
BTN2A2 -6151.0
PIK3CD -6147.0
UBE2E1 -6131.0
FYN -6117.0
NCF4 -6094.0
PAK2 -6088.0
SIGLEC12 -6057.5
SIGLEC7 -6057.5
SIGLEC8 -6057.5
SIGLEC9 -6057.5
TRAIP -5968.0
CRTAM -5937.0
CD247 -5933.0
PSMB1 -5931.0
RNF4 -5915.0
AKT2 -5897.0
FBXO40 -5893.0
KIF20A -5872.0
SEC61G -5830.0
HLA-DOA -5812.0
SYK -5699.0
FBXO15 -5695.0
RNF217 -5691.0
RBBP6 -5612.0
PSMB4 -5607.0
RICTOR -5595.0
SPTBN2 -5593.0
UBE2Q2 -5545.0
SEC13 -5544.0
ACTR10 -5539.0
ICAM5 -5517.0
SNAP23 -5495.0
UBE4A -5481.0
CDC20 -5454.0
COLEC12 -5439.0
TREM1 -5414.0
PSMD5 -5412.0
HLA-DOB -5373.0
ASB8 -5356.0
UBR1 -5334.0
CTSS -5320.0
CD1D -5308.0
MRC2 -5303.0
PIANP -5292.0
SLAMF7 -5287.0
WWP1 -5285.0
DET1 -5265.5
GRAP2 -5255.0
KIF2C -5213.0
TREM2 -5197.0
KIF11 -5195.0
MALT1 -5170.0
RASGRP1 -5127.0
PSMA3 -5078.0
KLRC1 -5053.5
PSMA2 -5050.5
IKBKB -5045.0
ANAPC1 -4990.0
TRIM69 -4969.0
MYD88 -4944.0
ASB5 -4907.0
KIF3B -4901.0
CD81 -4889.0
CD3E -4862.0
RNF138 -4854.0
SEC61B -4808.0
ORAI1 -4788.0
ASB14 -4769.0
VAV1 -4760.0
DAPP1 -4730.0
CDC34 -4678.0
NFKBIE -4652.0
ANAPC4 -4616.0
UBE2G1 -4613.0
HUWE1 -4598.0
ITK -4571.0
KIF2A -4566.0
SIAH2 -4552.0
SEC24D -4488.0
HECTD1 -4471.0
UBE2S -4447.0
FBXO22 -4409.0
KLHL13 -4338.0
KIF5B -4217.0
GLMN -4209.0
ATG7 -4196.0
ASB16 -4168.0
DCTN6 -4150.0
ARF1 -4106.0
PPP3CA -4087.0
PSMD14 -4055.0
PRKCQ -3997.0
TREML4 -3987.0
DNM1 -3955.0
CD80 -3926.0
RAET1E -3907.5
CD3D -3905.0
SIGLEC10 -3863.5
SIGLEC11 -3863.5
PSMD8 -3851.0
PDCD1LG2 -3847.0
AP2S1 -3795.0
PTPN11 -3777.0
HACE1 -3725.0
CD8A -3675.0
CD79B -3668.0
PSMB3 -3665.0
CUL5 -3575.0
MADCAM1 -3488.0
ITCH -3484.0
INPP5D -3469.0
DCTN5 -3442.0
KIR2DL1 -3436.0
KIR2DL3 -3436.0
KIR2DL4 -3436.0
KIR3DL1 -3436.0
KIR3DL2 -3436.0
PSMC2 -3419.0
UBE2D1 -3359.0
PSMD6 -3353.0
DCTN2 -3343.0
RBX1 -3219.0
CD3G -3199.0
CD8B -3184.5
HERC4 -3166.0
AP1S1 -3138.0
TLR4 -3119.0
PSMD4 -3118.0
DYNC1I1 -3094.0
CDC27 -3085.0
CTSC -3056.0
MAP3K7 -3011.0
PSMC4 -3007.0
KLRK1 -3000.0
SPSB2 -2956.0
UNKL -2939.0
CAPZB -2925.0
RAP1A -2869.0
CD34 -2848.0
SLAMF6 -2843.0
UBE2B -2819.0
UBE2A -2808.0
ARIH2 -2782.0
LCP2 -2749.0
LAT -2726.0
PIK3CA -2711.0
CTSV -2661.0
HERC1 -2594.0
PSMA7 -2576.0
ASB1 -2539.0
PDIA3 -2534.0
BTN1A1 -2521.0
KLRB1 -2512.0
PTPRJ -2509.0
UBA6 -2493.0
CYBB -2489.0
LGMN -2445.0
ANAPC5 -2429.0
PSMA1 -2388.0
DYNLL2 -2370.0
PSMD2 -2319.0
KIF23 -2270.0
AP1S3 -2255.0
SH3GL2 -2205.0
CHUK -2181.0
TRAT1 -2158.0
LRR1 -2137.0
KLRD1 -2105.0
PSMD1 -2102.0
CD14 -2079.0
AP1M2 -2078.0
TRIM63 -2072.0
PIK3R2 -2014.5
LRSAM1 -1949.0
RNF130 -1887.0
THOP1 -1875.0
KCTD7 -1869.0
ASB17 -1856.0
LRRC41 -1846.0
CLTC -1818.0
MYLIP -1810.0
CD209 -1809.0
IGKV1-12 -1796.5
IGKV1-16 -1796.5
IGKV1-17 -1796.5
IGKV1-39 -1796.5
IGKV1-5 -1796.5
IGKV1D-12 -1796.5
IGKV1D-16 -1796.5
IGKV1D-39 -1796.5
ICOSLG -1745.5
CTSE -1724.0
RNF14 -1694.0
CTSA -1693.0
BCL10 -1692.0
PSMA8 -1679.0
TRIM71 -1667.0
UBE2Q1 -1598.0
UBE3B -1546.0
PSMC6 -1541.0
SOS1 -1475.0
KLHL25 -1463.0
ZNRF2 -1453.0
IFITM1 -1331.0
IGLV6-57 -1290.0
LAG3 -1255.0
TRIM9 -1241.0
VAMP8 -1223.0
RAF1 -1207.0
CTLA4 -1200.0
PSMD11 -1181.0
DYNLL1 -1170.0
PSMD3 -1168.0
ITGB2 -1161.0
FBXW9 -1016.0
CANX -1011.0
NEDD4L -1007.0
ICOS -1002.0
DCTN3 -958.0
FBXW2 -936.0
FBXL13 -911.0
SELL -825.0
CYBA -615.0
ORAI2 -614.0
PSMA5 -604.0
ICAM4 -501.0
IGHV4-34 -409.5
IGHV4-39 -409.5
IGHV4-59 -409.5
RAP1B -396.0
RLIM -359.0
CUL2 -316.0
BTRC -286.0
SEC22B -266.0
DNM3 -262.0
KIF3A -186.0
UBE2N -184.5
SEC24B -161.0
AP2A2 -158.0
PSMB5 -153.0
FBXL20 -149.0
TLR1 -140.0
KLHL41 -93.0
SKP1 -82.0
UBE2L6 -52.0
PTEN 0.0
SOCS1 48.0
CD300E 245.0
TPP2 306.0
PSMD7 321.0
UBE2V2 339.0
RNF115 347.0
VAMP3 439.0
FBXO11 455.0
LTN1 472.0
PPP2CA 497.0
OSCAR 529.0
HLA-A 538.5
HLA-B 538.5
HLA-C 538.5
HLA-E 538.5
HLA-F 538.5
HLA-G 538.5
HSPA5 605.0
RNF6 612.0
RNF41 712.0
XDH 745.0
RNF126 846.0
LCK 916.0
CDC23 954.0
ICAM1 971.0
REL 978.0
TRIM41 981.0
MLST8 1003.0
UBC 1013.0
PSMC1 1107.0
TNFRSF14 1133.0
KIF22 1149.0
IKBKG 1225.0
UBA5 1329.0
FBXO2 1361.0
FBXL5 1446.0
MAPKAP1 1449.0
CALR 1483.0
PSME4 1510.0
PSMB2 1548.0
PPP2R5B 1592.0
RNF213 1594.0
RILP 1602.0
ASB4 1606.0
PAG1 1610.0
TRIM50 1674.0
CD274 1677.0
HECW2 1715.0
FBXO9 1763.0
TREML1 1797.0
FBXL3 1810.0
RIPK2 1837.0
CD40LG 1866.0
BLNK 1874.0
PPP2CB 1876.0
MIB2 1900.0
KIF15 1913.0
PLCG2 1922.0
PPL 1950.0
B2M 2072.0
SEC61A1 2087.0
NECTIN2 2095.0
KLHL21 2169.0
KCTD6 2174.0
ITGAL 2183.0
FBXO30 2192.0
FBXL19 2218.0
PSME2 2230.0
PSMC3 2256.0
NFKBIB 2261.0
SIPA1 2293.0
PPP2R5E 2334.0
ZBTB16 2341.0
FBXL22 2422.0
UBE2G2 2507.0
EVL 2510.0
ACTR1B 2529.0
KLC2 2543.0
RNF114 2572.0
UBR4 2668.0
NCR3 2749.0
BTNL2 2764.0
PDPK1 2786.0
UBA3 2804.0
ASB2 2898.0
DYNC1LI1 2899.0
IGKC 2909.0
SKP2 2932.0
CD226 3085.0
GRB2 3145.0
UFL1 3185.0
PLCG1 3263.0
UBR2 3270.0
MAP3K8 3271.0
CENPE 3317.0
RACGAP1 3339.0
ASB18 3344.0
LNPEP 3368.0
CDH1 3439.0
AKT1 3530.0
RNF34 3705.0
RNF19A 3706.0
CXADR 3737.0
LYN 3765.0
SMURF2 3791.0
PPP2R1A 3805.0
ANAPC2 3809.0
KLHL11 3855.0
NPEPPS 3858.0
FBXL7 3861.0
FBXL18 3867.0
CD28 3868.0
BTLA 3870.0
MKRN1 3907.0
GAN 3943.0
RELA 3959.0
DNM2 3996.0
FBXL16 4011.0
KIF5A 4021.0
LONRF1 4045.0
DTX3L 4070.0
PSMD12 4108.0
FBXO7 4174.0
AREL1 4178.0
ENAH 4245.0
CD40 4249.0
UBE2Z 4263.0
CTSB 4265.0
TRAF6 4327.0
SIAH1 4415.0
NRAS 4434.0
RAB7A 4453.0
RNF220 4493.0
PSMD13 4498.0
PRKACA 4516.0
PIK3R3 4535.5
TRIM32 4589.0
FBXW10 4596.5
AP1S2 4644.0
ITGB1 4674.0
YWHAB 4694.0
ICAM2 4707.0
HERC6 4719.0
NFATC2 4760.0
KLRG1 4769.0
PTPN22 4790.0
FBXL15 4811.0
CSK 4821.0
FBXL8 4827.5
TAPBP 4863.0
RNF182 4884.0
UBE2K 4934.0
KEAP1 4980.0
PSMB9 5019.0
ITPR2 5073.0
VHL 5081.0
KIF4A 5211.0
BLK 5218.0
HECTD3 5245.0
AP1M1 5259.0
FBXW5 5268.0
SPSB4 5357.0
FBXO21 5361.0
SH3RF1 5392.0
UBE2W 5409.5
ASB13 5422.0
TRIM11 5444.0
MGRN1 5507.0
KLC3 5514.0
CLEC4G 5542.0
TAP2 5583.5
FZR1 5603.0
BTNL9 5608.0
TRAF7 5613.0
CTSF 5650.0
FBXO32 5712.0
PPP2R5D 5723.0
UBA7 5741.0
UBE2M 5773.0
ACTR1A 5779.0
CTSD 5806.5
DCTN1 5822.5
AP2A1 5853.0
KLC4 5877.0
TRIB3 5887.0
FBXW11 5901.0
NFKB1 6004.0
CCNF 6074.0
BTBD6 6075.0
RNF111 6089.0
TRIM36 6098.0
PSMF1 6184.0
TRIM21 6196.0
FBXO27 6259.0
BTBD1 6294.0
RNF123 6354.0
RAP1GAP 6468.0
FBXO17 6476.0
FBXO6 6483.0
KIF3C 6498.0
UBE2H 6523.0
CD79A 6531.0
IFI30 6556.0
HERC3 6573.5
ERAP1 6578.0
SMURF1 6601.0
PSME1 6608.0
CDC16 6620.0
KLHL5 6676.0
FBXO10 6690.0
UBE2J2 6724.0
KBTBD8 6752.0
AKT3 6761.0
ASB10 6762.0
KLHL2 6767.0
KBTBD6 6824.5
KBTBD7 6824.5
UBE2R2 6861.0
YWHAZ 6876.0
THEM4 6916.0
ANAPC7 6926.0
C3 6951.0
ITPR1 6954.0
UBE2O 7003.0
RAPGEF3 7075.0
ASB7 7126.0
ITPR3 7138.0
STUB1 7195.0
KIF5C 7239.0
CD19 7249.0
ZNRF1 7259.0
NCK1 7272.0
UBA1 7293.0
CD300LG 7303.0
RNF144B 7313.0
VCAM1 7321.0
TLR6 7322.0
CD96 7332.0
CLTA 7341.0
AP1B1 7359.0
SEC31A 7378.0
FCGR3A 7385.5
NFATC1 7397.0
PIK3R1 7450.0
TRPC1 7501.0
PSMB8 7523.0
CD36 7608.0
LMO7 7618.0
ASB15 7642.0
HLA-DMB 7645.5
OSBPL1A 7651.0
RAPGEF4 7690.0
CD200 7711.0
RAC1 7746.0
DYNC1H1 7820.0
RAP1GAP2 7828.0
ASB3 7830.0
FBXW8 7847.0
MTOR 7871.0
KIF26A 7918.0
AP2M1 7919.0
AHCYL1 7929.0
AP2B1 7931.0
TAP1 7947.0
RBCK1 7983.0
NCF1 8002.0
TRIM39 8048.0
ITGAV 8087.0
SH3KBP1 8091.0
STIM1 8152.0


Transport of small molecules

Transport of small molecules
1326
set Transport of small molecules
setSize 656
pANOVA 3.34e-05
s.dist 0.0954
p.adjustANOVA 0.00114



Top enriched genes

Top 20 genes
GeneID Gene Rank
SLC12A7 8153
SLC4A10 8147
ABCB4 8143
SLC8A1 8118
ATP2B2 8113
ANO2 8082
ATP2A3 8057
ABCB6 8047
ALAD 8036
HMOX2 8031
SLC2A1 8017
SLC12A6 8015
ATP6V1A 8014
ATP6V0A2 8004
SPG7 7999
TPCN1 7984
ANO4 7982
LIPA 7953
SLCO1A2 7943
AP2B1 7931

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SLC12A7 8153.0
SLC4A10 8147.0
ABCB4 8143.0
SLC8A1 8118.0
ATP2B2 8113.0
ANO2 8082.0
ATP2A3 8057.0
ABCB6 8047.0
ALAD 8036.0
HMOX2 8031.0
SLC2A1 8017.0
SLC12A6 8015.0
ATP6V1A 8014.0
ATP6V0A2 8004.0
SPG7 7999.0
TPCN1 7984.0
ANO4 7982.0
LIPA 7953.0
SLCO1A2 7943.0
AP2B1 7931.0
AP2M1 7919.0
ATP6V0A1 7887.0
ATP2B4 7877.0
ADCY4 7870.0
CTNS 7866.0
ATP1A2 7846.0
ATP1B1 7826.0
NCEH1 7823.0
SLC5A6 7796.0
ADD1 7776.0
VDAC2 7762.0
SLC11A2 7747.0
SLC29A4 7735.0
SLC26A7 7695.0
SLC22A4 7678.0
ABCF1 7674.0
GNB3 7673.0
NGB 7665.0
AKAP1 7638.0
ABCB7 7604.0
ABCA7 7600.0
LRRC8A 7593.0
BSG 7570.0
TFRC 7569.0
SLC2A2 7562.0
SLC25A29 7560.0
NIPAL1 7559.0
PSMB8 7523.0
PHB2 7517.0
SLC44A1 7506.0
CA2 7502.0
TRPC1 7501.0
PEX19 7473.0
ADCY8 7470.0
SLC38A1 7441.0
SLC41A1 7439.0
LETM1 7437.0
SLC22A1 7430.0
SLC6A6 7423.0
ADCY6 7405.0
FXYD6 7395.0
SLC35B2 7343.0
CLTA 7341.0
SLC2A12 7317.0
MCU 7308.0
SLC25A22 7276.0
CYB5RL 7268.5
SLC4A7 7242.0
ABCC6 7235.0
SLC6A15 7201.0
DMTN 7200.0
SLCO1B1 7114.0
SLCO1B3 7114.0
ARL2 7084.0
RYR2 7076.0
SLC17A3 7070.0
CA4 7059.0
SLC4A1 7043.0
ABCG1 7040.0
PMPCA 7035.0
SLC1A7 7013.0
SOAT1 7010.0
LDLRAP1 6882.0
SLC2A4 6860.0
SLC33A1 6857.0
TTYH3 6854.0
SLC20A2 6838.0
SEL1L 6795.0
SLC27A1 6792.0
APOC2 6777.5
ABCD3 6773.0
WNK4 6772.0
ABCA6 6677.0
ADCY9 6648.0
PSME1 6608.0
ATP6V0C 6595.0
SLC11A1 6568.0
PARL 6562.5
ABCG4 6555.0
SLC26A1 6532.0
ABCB10 6463.0
SLC25A26 6437.0
ABCD1 6427.0
SLC17A7 6408.0
ATP2A2 6396.0
SLC25A5 6360.0
SLC43A2 6351.0
ATP1A1 6348.0
ATP13A2 6341.0
WNK2 6340.0
ANKH 6248.0
SLC7A1 6232.0
SLC35D1 6230.0
NIPAL3 6187.0
PSMF1 6184.0
SLC30A3 6165.0
ABCB8 6147.0
SLC9A1 6140.0
MB 6054.0
AQP7 6016.5
FKBP1B 5990.0
LMF1 5971.0
SLC1A2 5955.0
GNG8 5873.0
AP2A1 5853.0
APOA5 5800.0
ATP7B 5782.0
SLC4A5 5706.0
SLC6A1 5695.0
SLCO3A1 5670.0
ACO1 5632.0
CREB3L3 5616.0
STEAP3 5610.0
OSTM1 5601.0
AFG3L2 5585.0
SLC35D2 5569.5
MCOLN3 5557.0
TUSC3 5549.0
SLC2A7 5518.0
PCSK9 5483.0
ATP2C2 5482.0
UNC80 5477.0
SLC38A2 5432.0
APOA2 5339.0
SLC12A4 5332.0
LPL 5325.0
GNG12 5320.0
ERLIN2 5306.0
LMF2 5276.0
ABCC1 5260.0
LRRC8E 5213.0
ATP6V0E2 5189.0
SLC20A1 5121.0
SLC30A1 5060.0
LPA 5058.0
CYB5R1 5022.0
PSMB9 5019.0
SLC6A2 5016.0
SLC9A3 4988.0
SLC22A7 4974.0
SRI 4965.0
ANGPTL3 4942.0
MRS2 4909.0
ATP12A 4907.0
ANO1 4876.0
SLC9A7 4849.0
SLC50A1 4796.0
TRPM4 4784.0
ABCA2 4783.0
PRKAR1A 4751.0
APOD 4746.0
APOC4 4730.0
LSR 4727.0
EMB 4726.0
ATP13A5 4724.0
SLC2A8 4708.0
APOA4 4672.0
SLC4A2 4654.0
SLC16A7 4632.0
CP 4601.0
TRPV4 4551.0
ATP4A 4543.0
PRKACA 4516.0
ATP8A2 4509.0
PSMD13 4498.0
SLC28A1 4479.0
ABCG8 4478.0
SLC17A8 4468.0
AQP1 4436.0
CLCN6 4423.0
SLC2A6 4412.0
SLC38A3 4403.0
OS9 4393.0
CLCN4 4369.0
ADCY5 4361.0
SLC5A5 4347.0
ATP1A4 4344.0
CYGB 4243.0
CLCA2 4231.0
SLC25A4 4136.0
PSMD12 4108.0
ZDHHC8 4101.0
SLC46A1 4034.0
SLC25A10 4009.5
ATP11B 3977.0
APOBR 3948.0
SLC6A12 3944.0
SLC44A4 3892.0
SLC36A2 3863.0
SLC39A10 3838.0
MCOLN1 3836.0
CLCN3 3833.0
SLC39A14 3829.0
ALB 3808.0
ATP8B3 3775.0
SLC3A2 3743.0
SLC22A17 3730.0
SLC15A4 3718.0
STEAP2 3677.0
LCN2 3656.0
VDAC1 3653.0
SLC4A4 3633.0
LIPG 3592.0
ATP13A1 3582.0
SLC44A5 3580.0
STOM 3571.0
SLC8A2 3568.0
AQP11 3545.0
SLC24A5 3525.0
RHBG 3509.0
MCUB 3469.0
LRRC8D 3465.0
SLC22A15 3434.0
ATP6V1C2 3394.0
ATP10B 3351.0
ANGPTL4 3332.0
ADD2 3247.0
ATP9A 3244.0
SOAT2 3238.0
SLC44A2 3226.0
ANO10 3213.0
SLC9A6 3203.0
TRPM5 3182.0
SLC27A4 3117.0
SLC13A4 3114.0
SLC16A1 3094.0
SLC12A1 3070.0
SLC30A6 3026.0
SLC7A6 3025.0
MICU2 2979.0
ASIC1 2969.0
SLC35A2 2960.0
NIPA1 2926.0
ATP6V1C1 2920.0
MICU1 2885.0
BMP1 2815.0
RAB11FIP2 2813.0
SGK3 2720.5
SLC24A2 2679.0
SLC39A2 2676.0
HMOX1 2671.0
LRRC8B 2666.0
SLC12A5 2661.0
NALCN 2641.0
SLC4A8 2612.0
SLC7A5 2601.0
GNB2 2595.0
GNB1 2583.0
SLC22A8 2502.0
ARL2BP 2500.0
HBA1 2471.5
SCNN1A 2420.0
SLC22A2 2395.0
SLCO2B1 2372.0
ANO9 2362.0
SLC25A18 2352.0
ATP6V1B2 2262.0
PSMC3 2256.0
SLC26A4 2239.0
PSME2 2230.0
GNG7 2130.0
GNB5 2123.0
SLC32A1 2101.0
PMPCB 2100.0
SLC28A2 2079.0
BSND 2054.0
VCP 2037.0
SLC47A1 2003.0
SLCO2A1 2000.0
NIPA2 1938.0
ASIC2 1918.0
SLC6A5 1917.0
FGF21 1908.0
DERL2 1865.0
SLC6A3 1858.0
ATP8A1 1828.0
ABCD2 1806.0
AQP8 1799.0
GNG2 1781.0
WNK3 1769.0
SLC34A3 1735.5
SLC17A6 1732.0
CAND1 1711.0
AZGP1 1695.0
DERL1 1681.0
SLC12A3 1675.0
SLC36A1 1603.0
PSMB2 1548.0
SLC30A10 1546.0
TRPA1 1536.0
BEST4 1513.0
PSME4 1510.0
PRKAR1B 1495.0
SLC35B4 1486.0
SLC5A1 1479.0
ABCB9 1461.0
FBXL5 1446.0
GNB4 1440.0
AQP2 1392.0
ATP6V0D1 1316.0
AMN 1309.0
AQP3 1301.0
LCN9 1276.0
SLC18A1 1266.0
P4HB 1245.0
ANO6 1195.0
LCN1 1182.0
ATP1A3 1164.5
SLC15A3 1113.0
CLCN2 1112.0
PSMC1 1107.0
TSC22D3 1052.0
RNF185 1043.0
SLC22A6 1027.0
RNF5 1020.0
UBC 1013.0
ABCC2 1006.0
SLC36A4 997.0
ABCC10 973.0
ABCG5 951.0
MIP 946.0
ATP10D 885.0
SLC3A1 858.0
AQP9 853.0
BEST3 847.0
CLCN7 720.0
SLC34A1 663.5
SLC5A4 622.0
SLC15A1 604.0
SLC5A10 592.0
LIPC 588.0
SLC9A8 512.0
TRPV5 481.0
SLC26A6 422.0
SLC24A3 417.0
ABCB5 385.0
CLCNKA 369.5
CLCNKB 369.5
NPC1 353.0
SLC7A9 325.0
PSMD7 321.0
SLC5A8 302.0
SLC1A6 247.0
AQP5 225.0
ATP6V1G3 225.0
FURIN 60.0
SKP1 -82.0
AVP -90.0
APOE -136.0
PSMB5 -153.0
AP2A2 -158.0
SLC6A11 -176.0
BEST1 -219.0
GNG10 -219.0
RAB11A -258.0
STOML2 -277.0
RHAG -305.0
VDAC3 -325.0
SLC13A1 -345.0
CLCA1 -361.0
VLDLR -387.0
ANGPTL8 -399.0
TRPM3 -437.0
ATP6V1B1 -443.0
ATP6V0E1 -470.0
SLC6A19 -503.0
SLC6A18 -520.0
KCNJ11 -540.0
CA1 -581.0
SLC31A1 -587.0
SCNN1G -594.0
PSMA5 -604.0
SLCO1C1 -633.0
SLC24A4 -810.0
MBTPS2 -837.0
TRPV2 -946.0
SLC13A5 -959.0
YME1L1 -990.0
NEDD4L -1007.0
SLC9B2 -1078.0
FXYD4 -1126.0
SLC5A12 -1126.0
TRPV6 -1126.0
SLC26A3 -1162.0
PSMD3 -1168.0
PSMD11 -1181.0
NR1H3 -1186.0
RAF1 -1207.0
NIPAL2 -1253.0
MCOLN2 -1350.0
NR1H2 -1366.0
SLC26A9 -1380.0
SLC5A11 -1410.0
SLC5A9 -1410.0
MYO5B -1444.5
CYB5R4 -1479.0
SLC24A1 -1486.0
ATP6V0D2 -1489.0
SLC22A3 -1492.0
ASIC5 -1495.0
FTMT -1532.0
AHCYL2 -1540.0
PSMC6 -1541.0
ATP2B3 -1554.0
ABCA12 -1617.0
SLC38A5 -1653.0
SLC39A6 -1676.0
PSMA8 -1679.0
APOB -1729.0
SLC16A2 -1761.0
TRPC4AP -1777.0
ATP13A4 -1806.0
MYLIP -1810.0
CLTC -1818.0
A2M -1891.0
SLC5A2 -1927.0
TRPC3 -1928.0
ANO8 -1929.0
GNG11 -1937.0
ATP10A -2027.0
APOC3 -2065.5
SLC5A7 -2065.5
FXYD1 -2086.0
SLC13A2 -2101.0
PSMD1 -2102.0
UNC79 -2185.0
ATP6V1E1 -2191.0
SLC13A3 -2200.0
ATP6AP1 -2220.0
ATP4B -2237.0
ATP6V1E2 -2246.0
ANO3 -2265.0
TTYH1 -2273.0
ADCY3 -2277.0
SLC30A5 -2293.0
PSMD2 -2319.0
TRPM8 -2333.0
RYR3 -2364.0
PCSK5 -2367.0
PSMA1 -2388.0
SLC29A3 -2395.0
ABCC4 -2420.0
SLC17A1 -2494.0
GLRX3 -2542.0
SGK2 -2566.0
PSMA7 -2576.0
CFTR -2632.0
SLC2A13 -2635.0
SLC45A3 -2735.0
ATP1B2 -2815.0
SLC26A2 -2832.0
SLC26A11 -2850.0
ATP6V1D -2852.0
SLC9A5 -2897.0
MIR32 -2910.0
SLC43A1 -2923.0
TCIRG1 -2929.0
CUTC -2950.0
GNG5 -2972.0
NEDD8 -2992.0
PSMC4 -3007.0
SLC12A2 -3024.0
ATP2A1 -3044.0
PSMD4 -3118.0
ATP2B1 -3182.0
SLCO4C1 -3230.0
LCAT -3245.0
ATP1B3 -3267.0
TRPM2 -3293.0
TRPC5 -3297.0
CLCN1 -3336.0
SLC4A9 -3342.0
PSMD6 -3353.0
SLC4A3 -3361.0
TRPV3 -3402.0
PSMC2 -3419.0
CAMK2G -3492.0
SLC28A3 -3523.0
SLC22A18 -3535.0
IREB2 -3556.0
SLC7A3 -3604.0
ASIC4 -3648.0
TRPM6 -3655.0
PSMB3 -3665.0
ATP6V0B -3671.0
SLC8B1 -3700.0
ABCA3 -3710.0
SLC1A1 -3714.0
AP2S1 -3795.0
SLC7A2 -3828.0
SLC39A3 -3841.0
PSMD8 -3851.0
HFE -3868.0
SLC34A2 -3898.0
SLC6A13 -3927.0
SLC35A1 -3954.0
CLCA4 -3977.0
ABCC9 -3996.0
NPC2 -4051.0
PSMD14 -4055.0
SLC9A2 -4068.0
TRPM7 -4095.0
SLC6A9 -4181.0
ERLEC1 -4213.0
SLC22A12 -4218.0
NIPAL4 -4251.0
PEX3 -4321.0
BEST2 -4325.0
TRPV1 -4342.0
ABCA9 -4400.0
RHCG -4437.0
SLC41A2 -4454.0
SLC14A2 -4481.0
GNG3 -4499.0
SLC27A6 -4582.0
SLC7A10 -4631.0
SLC39A5 -4658.0
ATP11A -4665.0
SLC39A8 -4683.0
ADCY2 -4754.0
SLC9C1 -4782.0
APOA1 -4811.0
SLC18A2 -4876.0
ASIC3 -4952.0
ADCY1 -5008.0
SLC35C1 -5036.0
SLC16A8 -5046.0
PSMA2 -5050.5
PSMA3 -5078.0
SLC35B3 -5115.0
DERL3 -5123.0
SLC1A3 -5153.0
ATP8B1 -5219.0
SLC30A7 -5261.0
SLC44A3 -5267.0
WWP1 -5285.0
SLC9A4 -5326.0
ADD3 -5398.0
PSMD5 -5412.0
ABCA5 -5428.0
TPCN2 -5457.5
SLC29A2 -5514.0
PSMB4 -5607.0
ATP6V1H -5756.0
EIF2S3 -5766.5
SLC40A1 -5771.0
HEPH -5816.0
PSMB1 -5931.0
SLC39A1 -6016.0
GNAS -6021.0
CLCN5 -6047.0
PLTP -6098.0
SCARB1 -6141.0
SLC2A10 -6156.0
ABCA4 -6183.0
SLC1A4 -6192.0
PSMB7 -6252.0
SCNN1B -6270.0
RSC1A1 -6272.0
LDLR -6289.0
ABCA8 -6320.0
MTTP -6324.0
PRKACB -6340.0
ABCA1 -6344.0
ATP9B -6355.0
MICU3 -6359.0
ATP8B2 -6360.0
TRPM1 -6401.0
EIF2S2 -6402.0
SLC7A7 -6426.0
ANO7 -6428.0
APOC1 -6439.0
ADCY7 -6487.0
SAR1B -6531.0
PSMC5 -6575.0
SLC8A3 -6593.0
ATP11C -6595.0
CUBN -6631.0
SLC16A10 -6644.0
CYBRD1 -6662.0
TFR2 -6666.0
SLC30A2 -6669.0
CALM1 -6675.0
SLC16A3 -6714.0
SLC14A1 -6788.0
TTYH2 -6797.0
SLC9A9 -6835.0
ABCC5 -6870.0
ERLIN1 -6880.0
RYR1 -6915.0
PSMB6 -6996.0
TRPC6 -7002.0
PRKAR2A -7003.0
SLC7A11 -7007.0
SLC15A2 -7011.0
EIF2S1 -7018.0
SLC2A9 -7074.0
CLIC2 -7084.0
FXYD2 -7136.5
SLC29A1 -7191.0
RUNX1 -7206.0
PSMA6 -7250.0
MBTPS1 -7280.0
SLC66A1 -7327.0
ATP8B4 -7331.0
CAMK2A -7362.0
CIDEC -7371.0
PSMA4 -7394.0
CUL1 -7405.0
SLCO4A1 -7409.0
STOML3 -7412.0
CAMK2B -7446.0
SLC1A5 -7484.0
PCSK6 -7514.0
ANO5 -7545.0
SLC38A4 -7551.0
RPS27A -7640.0
SGK1 -7659.0
SLC10A6 -7702.0
TRPC4 -7744.0
ABCC3 -7823.0
MFSD4B -7888.0
CYB5R2 -7891.0
SLC39A4 -7900.0
WNK1 -7918.0
SLC7A8 -7923.0
HDLBP -7956.0
ATP2C1 -7973.0
FTL -7977.0
FLVCR1 -8055.0
MAGT1 -8123.0
TRDN -8124.0
SLC6A7 -8151.0
PRKAR2B -8171.0
ATP7A -8245.0
AQP4 -8269.0


Peroxisomal lipid metabolism

Peroxisomal lipid metabolism
836
set Peroxisomal lipid metabolism
setSize 27
pANOVA 3.54e-05
s.dist 0.46
p.adjustANOVA 0.00118



Top enriched genes

Top 20 genes
GeneID Gene Rank
NUDT7 8063
SLC27A2 7786
HAO2 7672
ACOX2 7644
HSD17B4 7497
CRAT 7368
ACOX1 7255
PHYH 7045
ALDH3A2 6988
AMACR 6750
ABCD1 6427
ACAA1 6125
EHHADH 6024
NUDT19 5464
ACOT6 4818
MLYCD 4748
ACBD5 4146
ACOT8 3216
HACL1 2573
ACOX3 2479

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NUDT7 8063
SLC27A2 7786
HAO2 7672
ACOX2 7644
HSD17B4 7497
CRAT 7368
ACOX1 7255
PHYH 7045
ALDH3A2 6988
AMACR 6750
ABCD1 6427
ACAA1 6125
EHHADH 6024
NUDT19 5464
ACOT6 4818
MLYCD 4748
ACBD5 4146
ACOT8 3216
HACL1 2573
ACOX3 2479
ACOXL 2122
PECR 1557
ACBD4 -269
ACOT4 -2617
SLC25A17 -5644
ECI2 -6476
CROT -8187


Synthesis of bile acids and bile salts

Synthesis of bile acids and bile salts
1212
set Synthesis of bile acids and bile salts
setSize 29
pANOVA 6.39e-05
s.dist 0.429
p.adjustANOVA 0.00209



Top enriched genes

Top 20 genes
GeneID Gene Rank
AKR1D1 7924
SLC27A2 7786
OSBPL1A 7651
ACOX2 7644
OSBPL9 7624
HSD17B4 7497
OSBPL6 7390
NCOA1 7218
SLC27A5 7037
AMACR 6750
ABCB11 6290
NR1H4 5883
BAAT 5784
OSBPL2 5717
NCOA2 5324
OSBPL3 4992
CYP7A1 4954
CYP27A1 4354
ACOT8 3216
CYP46A1 2984

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AKR1D1 7924
SLC27A2 7786
OSBPL1A 7651
ACOX2 7644
OSBPL9 7624
HSD17B4 7497
OSBPL6 7390
NCOA1 7218
SLC27A5 7037
AMACR 6750
ABCB11 6290
NR1H4 5883
BAAT 5784
OSBPL2 5717
NCOA2 5324
OSBPL3 4992
CYP7A1 4954
CYP27A1 4354
ACOT8 3216
CYP46A1 2984
PTGIS 2632
OSBP 2607
CYP8B1 2544
RXRA -1980
HSD3B7 -2383
CYP39A1 -4425
CH25H -7050
OSBPL7 -7479
CYP7B1 -7839


Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol

Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
1215
set Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
setSize 19
pANOVA 8e-05
s.dist 0.523
p.adjustANOVA 0.00255



Top enriched genes

Top 20 genes
GeneID Gene Rank
AKR1D1 7924
SLC27A2 7786
ACOX2 7644
HSD17B4 7497
NCOA1 7218
SLC27A5 7037
AMACR 6750
ABCB11 6290
NR1H4 5883
BAAT 5784
NCOA2 5324
CYP7A1 4954
CYP27A1 4354
ACOT8 3216
PTGIS 2632
CYP8B1 2544
RXRA -1980
HSD3B7 -2383
CYP7B1 -7839

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AKR1D1 7924
SLC27A2 7786
ACOX2 7644
HSD17B4 7497
NCOA1 7218
SLC27A5 7037
AMACR 6750
ABCB11 6290
NR1H4 5883
BAAT 5784
NCOA2 5324
CYP7A1 4954
CYP27A1 4354
ACOT8 3216
PTGIS 2632
CYP8B1 2544
RXRA -1980
HSD3B7 -2383
CYP7B1 -7839


Separation of Sister Chromatids

Separation of Sister Chromatids
1099
set Separation of Sister Chromatids
setSize 157
pANOVA 0.000167
s.dist -0.174
p.adjustANOVA 0.0052



Top enriched genes

Top 20 genes
GeneID Gene Rank
DYNC1LI2 -8117
KIF18A -7894
RPS27A -7640
MAPRE1 -7594
SGO2 -7553
NDC80 -7482
RANBP2 -7410
PSMA4 -7394
DYNC1I2 -7307
PSMA6 -7250
NSL1 -7209
PDS5B -7204
CENPK -7198
ZWILCH -7171
CENPM -7089
ANAPC10 -7079
PPP2R5A -7024
PSMB6 -6996
PPP2R1B -6978
PPP2R5C -6762

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DYNC1LI2 -8117.0
KIF18A -7894.0
RPS27A -7640.0
MAPRE1 -7594.0
SGO2 -7553.0
NDC80 -7482.0
RANBP2 -7410.0
PSMA4 -7394.0
DYNC1I2 -7307.0
PSMA6 -7250.0
NSL1 -7209.0
PDS5B -7204.0
CENPK -7198.0
ZWILCH -7171.0
CENPM -7089.0
ANAPC10 -7079.0
PPP2R5A -7024.0
PSMB6 -6996.0
PPP2R1B -6978.0
PPP2R5C -6762.0
NUP43 -6740.0
ESPL1 -6668.0
PSMC5 -6575.0
ITGB3BP -6486.0
STAG1 -6464.0
BIRC5 -6388.0
UBE2C -6382.0
CENPL -6358.0
PSMB7 -6252.0
UBE2E1 -6131.0
PSMB1 -5931.0
NUF2 -5692.0
PDS5A -5677.0
NUP160 -5641.0
PSMB4 -5607.0
PTTG1 -5560.5
SEC13 -5544.0
CDC20 -5454.0
NDEL1 -5451.0
PSMD5 -5412.0
KNTC1 -5312.0
STAG2 -5293.0
KIF2C -5213.0
PSMA3 -5078.0
PSMA2 -5050.5
ZWINT -5019.0
ANAPC1 -4990.0
CENPA -4978.0
CENPF -4787.0
CENPU -4727.0
NUP107 -4634.0
ANAPC4 -4616.0
KIF2A -4566.0
SPDL1 -4476.0
UBE2S -4447.0
SPC25 -4427.0
WAPL -4097.0
PSMD14 -4055.0
PSMD8 -3851.0
ANAPC16 -3705.0
PSMB3 -3665.0
BUB1B -3498.5
PSMC2 -3419.0
UBE2D1 -3359.0
PSMD6 -3353.0
PSMD4 -3118.0
DYNC1I1 -3094.0
CDC27 -3085.0
BUB3 -3061.0
SPC24 -3045.0
PSMC4 -3007.0
ERCC6L -2999.0
PSMA7 -2576.0
CENPP -2558.0
CDCA8 -2497.0
KNL1 -2495.0
ANAPC5 -2429.0
PSMA1 -2388.0
DYNLL2 -2370.0
PLK1 -2358.0
PSMD2 -2319.0
CENPT -2217.0
CDCA5 -2194.0
PSMD1 -2102.0
NUDC -1938.0
ANAPC15 -1852.0
CKAP5 -1758.0
PSMA8 -1679.0
PSMC6 -1541.0
CENPH -1458.0
CENPI -1365.0
INCENP -1351.0
SKA1 -1240.0
PSMD11 -1181.0
DYNLL1 -1170.0
PSMD3 -1168.0
PSMA5 -604.0
CENPC -183.0
PSMB5 -153.0
HDAC8 -113.5
TAOK1 -79.0
PSMD7 321.0
NUP37 424.0
PPP2CA 497.0
PAFAH1B1 869.0
CENPO 895.0
CDC23 954.0
MAD1L1 988.0
UBC 1013.0
PSMC1 1107.0
MAD2L1 1260.0
SMC1A 1369.0
DSN1 1476.0
CENPQ 1492.0
PSME4 1510.0
PSMB2 1548.0
PPP2R5B 1592.0
PPP2CB 1876.0
XPO1 2059.0
SKA2 2089.0
PSME2 2230.0
PSMC3 2256.0
PPP2R5E 2334.0
B9D2 2398.0
AURKB 2419.0
NUP85 2708.0
SGO1 2870.0
DYNC1LI1 2899.0
ZW10 3246.0
CENPE 3317.0
PPP2R1A 3805.0
ANAPC2 3809.0
RCC2 3900.0
PSMD12 4108.0
PSMD13 4498.0
NUP98 4522.0
NDE1 4587.0
BUB1 4819.0
PSMB9 5019.0
NUP133 5700.0
PPP2R5D 5723.0
CENPN 5911.0
PSMF1 6184.0
SMC3 6522.0
PSME1 6608.0
CDC16 6620.0
CLASP2 6800.0
PMF1 6871.0
ANAPC7 6926.0
AHCTF1 7008.0
RAD21 7098.0
PSMB8 7523.0
PPP1CC 7613.0
RANGAP1 7699.0
DYNC1H1 7820.0
CLIP1 8035.0
CLASP1 8148.0


Generation of second messenger molecules

Generation of second messenger molecules
469
set Generation of second messenger molecules
setSize 24
pANOVA 2e-04
s.dist -0.438
p.adjustANOVA 0.00612



Top enriched genes

Top 20 genes
GeneID Gene Rank
HLA-DQB1 -8259.5
HLA-DQB2 -8259.5
HLA-DRA -8140.0
CD101 -7849.0
PAK3 -7738.0
PAK1 -7605.0
VASP -7374.0
WAS -6934.0
TRBC1 -6620.5
PAK2 -6088.0
CD247 -5933.0
GRAP2 -5255.0
CD3E -4862.0
ITK -4571.0
CD3D -3905.0
CD3G -3199.0
LCP2 -2749.0
LAT -2726.0
LCK 916.0
PLCG2 1922.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
HLA-DQB1 -8259.5
HLA-DQB2 -8259.5
HLA-DRA -8140.0
CD101 -7849.0
PAK3 -7738.0
PAK1 -7605.0
VASP -7374.0
WAS -6934.0
TRBC1 -6620.5
PAK2 -6088.0
CD247 -5933.0
GRAP2 -5255.0
CD3E -4862.0
ITK -4571.0
CD3D -3905.0
CD3G -3199.0
LCP2 -2749.0
LAT -2726.0
LCK 916.0
PLCG2 1922.0
EVL 2510.0
PLCG1 3263.0
ENAH 4245.0
NCK1 7272.0


TCR signaling

TCR signaling
1226
set TCR signaling
setSize 96
pANOVA 0.000289
s.dist -0.214
p.adjustANOVA 0.00863



Top enriched genes

Top 20 genes
GeneID Gene Rank
PTPRC -8287.0
HLA-DQB1 -8259.5
HLA-DQB2 -8259.5
HLA-DRA -8140.0
CD101 -7849.0
PAK3 -7738.0
RPS27A -7640.0
PAK1 -7605.0
CUL1 -7405.0
PSMA4 -7394.0
VASP -7374.0
PSMA6 -7250.0
PSMB6 -6996.0
TAB2 -6989.0
WAS -6934.0
TRBC1 -6620.5
PSMC5 -6575.0
PSMB7 -6252.0
PAK2 -6088.0
CD247 -5933.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PTPRC -8287.0
HLA-DQB1 -8259.5
HLA-DQB2 -8259.5
HLA-DRA -8140.0
CD101 -7849.0
PAK3 -7738.0
RPS27A -7640.0
PAK1 -7605.0
CUL1 -7405.0
PSMA4 -7394.0
VASP -7374.0
PSMA6 -7250.0
PSMB6 -6996.0
TAB2 -6989.0
WAS -6934.0
TRBC1 -6620.5
PSMC5 -6575.0
PSMB7 -6252.0
PAK2 -6088.0
CD247 -5933.0
PSMB1 -5931.0
PSMB4 -5607.0
PSMD5 -5412.0
GRAP2 -5255.0
MALT1 -5170.0
PSMA3 -5078.0
PSMA2 -5050.5
IKBKB -5045.0
CD3E -4862.0
CDC34 -4678.0
ITK -4571.0
PSMD14 -4055.0
PRKCQ -3997.0
CD3D -3905.0
PSMD8 -3851.0
PSMB3 -3665.0
INPP5D -3469.0
PSMC2 -3419.0
UBE2D1 -3359.0
PSMD6 -3353.0
CD3G -3199.0
PSMD4 -3118.0
MAP3K7 -3011.0
PSMC4 -3007.0
LCP2 -2749.0
LAT -2726.0
PIK3CA -2711.0
PSMA7 -2576.0
PTPRJ -2509.0
PSMA1 -2388.0
PSMD2 -2319.0
CHUK -2181.0
TRAT1 -2158.0
PSMD1 -2102.0
PIK3R2 -2014.5
BCL10 -1692.0
PSMA8 -1679.0
PSMC6 -1541.0
PSMD11 -1181.0
PSMD3 -1168.0
PSMA5 -604.0
BTRC -286.0
UBE2N -184.5
PSMB5 -153.0
SKP1 -82.0
PTEN 0.0
PSMD7 321.0
LCK 916.0
UBC 1013.0
PSMC1 1107.0
IKBKG 1225.0
PSME4 1510.0
PSMB2 1548.0
PAG1 1610.0
RIPK2 1837.0
PLCG2 1922.0
PSME2 2230.0
PSMC3 2256.0
EVL 2510.0
PDPK1 2786.0
PLCG1 3263.0
RELA 3959.0
PSMD12 4108.0
ENAH 4245.0
TRAF6 4327.0
PSMD13 4498.0
PTPN22 4790.0
CSK 4821.0
PSMB9 5019.0
FBXW11 5901.0
NFKB1 6004.0
PSMF1 6184.0
PSME1 6608.0
NCK1 7272.0
PIK3R1 7450.0
PSMB8 7523.0


Complex I biogenesis

Complex I biogenesis
210
set Complex I biogenesis
setSize 46
pANOVA 0.000344
s.dist 0.305
p.adjustANOVA 0.0101



Top enriched genes

Top 20 genes
GeneID Gene Rank
NDUFA10 7483
NDUFA8 7131
NDUFA12 7130
NDUFAB1 6996
ECSIT 6963
NDUFV1 6489
ACAD9 6453
NDUFA9 6209
NDUFB10 6086
NDUFS5 5612
MT-ND1 5579
NDUFB7 5573
NDUFV3 5524
NDUFAF7 5479
NDUFB6 4983
MT-ND5 4937
MT-ND2 4879
TIMMDC1 4862
MT-ND6 4767
MT-ND4 4382

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NDUFA10 7483.0
NDUFA8 7131.0
NDUFA12 7130.0
NDUFAB1 6996.0
ECSIT 6963.0
NDUFV1 6489.0
ACAD9 6453.0
NDUFA9 6209.0
NDUFB10 6086.0
NDUFS5 5612.0
MT-ND1 5579.0
NDUFB7 5573.0
NDUFV3 5524.0
NDUFAF7 5479.0
NDUFB6 4983.0
MT-ND5 4937.0
MT-ND2 4879.0
TIMMDC1 4862.0
MT-ND6 4767.0
MT-ND4 4382.0
NDUFS3 4380.0
NDUFB11 4068.0
NDUFAF3 3956.0
NDUFS1 3819.0
NDUFS8 3493.0
NDUFS7 3090.0
NDUFB4 2890.0
NDUFAF6 2862.0
NDUFA6 2222.0
NDUFS4 2132.0
NDUFAF4 1307.0
NDUFAF1 1191.0
NDUFB8 1015.5
NDUFA13 544.0
NDUFA3 -953.0
NDUFB5 -1930.0
NDUFV2 -2183.0
NDUFC2 -3052.5
MT-ND3 -3112.0
NDUFA11 -3345.5
NUBPL -3355.0
NDUFA2 -3380.0
NDUFS2 -3401.0
NDUFAF5 -4827.0
TMEM126B -5318.0
NDUFB3 -6948.0


PD-1 signaling

PD-1 signaling
801
set PD-1 signaling
setSize 15
pANOVA 0.000593
s.dist -0.512
p.adjustANOVA 0.017



Top enriched genes

Top 20 genes
GeneID Gene Rank
HLA-DQB1 -8259.5
HLA-DQB2 -8259.5
PTPN6 -8219.0
HLA-DRA -8140.0
TRBC1 -6620.5
PDCD1 -6489.0
CD247 -5933.0
CD3E -4862.0
CD3D -3905.0
PDCD1LG2 -3847.0
PTPN11 -3777.0
CD3G -3199.0
LCK 916.0
CD274 1677.0
CSK 4821.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
HLA-DQB1 -8259.5
HLA-DQB2 -8259.5
PTPN6 -8219.0
HLA-DRA -8140.0
TRBC1 -6620.5
PDCD1 -6489.0
CD247 -5933.0
CD3E -4862.0
CD3D -3905.0
PDCD1LG2 -3847.0
PTPN11 -3777.0
CD3G -3199.0
LCK 916.0
CD274 1677.0
CSK 4821.0


Protein localization

Protein localization
897
set Protein localization
setSize 144
pANOVA 0.000618
s.dist 0.165
p.adjustANOVA 0.0173



Top enriched genes

Top 20 genes
GeneID Gene Rank
NUDT7 8063.0
TIMM50 7840.0
SLC27A2 7786.0
GRPEL1 7779.0
MTX1 7773.0
LONP2 7750.0
LDHD 7733.0
HAO2 7672.0
ACOX2 7644.0
ACOT2 7508.5
APP 7507.0
HSD17B4 7497.0
PEX19 7473.0
ACO2 7469.0
TIMM44 7410.0
CRAT 7368.0
CS 7355.0
ACOX1 7255.0
PHYH 7045.0
PMPCA 7035.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NUDT7 8063.0
TIMM50 7840.0
SLC27A2 7786.0
GRPEL1 7779.0
MTX1 7773.0
LONP2 7750.0
LDHD 7733.0
HAO2 7672.0
ACOX2 7644.0
ACOT2 7508.5
APP 7507.0
HSD17B4 7497.0
PEX19 7473.0
ACO2 7469.0
TIMM44 7410.0
CRAT 7368.0
CS 7355.0
ACOX1 7255.0
PHYH 7045.0
PMPCA 7035.0
ALDH3A2 6988.0
ABCD3 6773.0
AMACR 6750.0
UBE2J2 6724.0
EMD 6675.0
SAMM50 6561.0
ATP5F1B 6480.0
ECH1 6452.0
ABCD1 6427.0
TIMM22 6422.0
VAMP2 6400.5
PITRM1 6359.0
IDH3G 6298.0
GNPAT 6274.0
TAZ 6238.0
PEX26 6222.0
SLC25A12 6148.0
ACAA1 6125.0
PEX7 6090.0
HSPA9 6038.0
EHHADH 6024.0
BAAT 5784.0
EPHX2 5626.0
NUDT19 5464.0
TOMM40 5429.0
CAT 5335.0
BAG6 5304.0
OTC 4960.0
CYC1 4883.0
MLYCD 4748.0
PXMP4 4429.0
PAOX 4192.5
GET3 4148.0
ACBD5 4146.0
TIMM17A 4145.0
SLC25A4 4136.0
DHRS4 4126.5
VDAC1 3653.0
MTX2 3387.0
CHCHD3 3262.0
ACOT8 3216.0
PEX12 3158.0
CHCHD10 3156.0
PXMP2 3147.0
HAO1 3075.0
TIMM21 2922.0
SLC25A13 2731.0
HMOX1 2671.0
CHCHD7 2631.0
HACL1 2573.0
HSPD1 2540.0
PEX11B 2503.0
ACOX3 2479.0
PEX5 2358.0
PEX6 2282.0
PMPCB 2100.0
FXN 1911.0
HMGCL 1875.0
ABCD2 1806.0
PEX10 1682.0
PECR 1557.0
BCS1L 1252.0
NDUFB8 1015.5
UBC 1013.0
PEX14 982.0
TOMM22 929.0
SGTA 760.0
COQ2 749.0
AGPS 484.0
TIMM13 265.0
TOMM20 -422.0
GSTK1 -481.0
TIMM8A -867.0
GDAP1 -1041.0
OTOF -1308.0
CHCHD2 -1467.0
PEX1 -1478.0
IDH1 -1627.0
TOMM70 -1868.0
DNAJC19 -2135.0
STX1A -2228.0
TIMM10 -2414.0
ACOT4 -2617.0
PRNP -2909.0
HSCB -3003.0
CHCHD5 -3068.0
CHCHD4 -3136.0
GET1 -3137.0
UBE2D1 -3359.0
PIPOX -3372.0
GFER -3386.0
PAM16 -3641.0
MPV17 -3835.0
STX5 -4049.0
PEX3 -4321.0
CAMLG -4503.0
IDE -4564.0
PEX16 -4578.0
ZFAND6 -4623.0
DAO -4749.0
SEC61B -4808.0
DDO -4966.0
TIMM23 -5484.0
TYSND1 -5636.0
SLC25A17 -5644.0
NOS2 -5755.0
SEC61G -5830.0
AGXT -6265.0
CMC4 -6302.0
ECI2 -6476.0
GET4 -6852.0
TOMM7 -7043.0
TIMM8B -7159.0
PEX13 -7177.0
PEX2 -7231.0
VAPA -7396.0
UBE2D3 -7462.0
COX19 -7585.0
RPS27A -7640.0
TIMM9 -7663.0
SERP1 -7703.0
USP9X -7812.0
TIMM10B -7813.5
CROT -8187.0


Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.2.0 (2022-04-22)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 20.04.4 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/liblapack.so.3
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.2.4               GGally_2.1.2               
##  [3] ggplot2_3.3.5               beeswarm_0.4.0             
##  [5] gtools_3.9.2                tibble_3.1.6               
##  [7] dplyr_1.0.8                 echarts4r_0.4.3            
##  [9] kableExtra_1.3.4            gplots_3.1.1               
## [11] mitch_1.5.1                 DESeq2_1.32.0              
## [13] SummarizedExperiment_1.22.0 Biobase_2.52.0             
## [15] MatrixGenerics_1.4.3        matrixStats_0.61.0         
## [17] GenomicRanges_1.44.0        GenomeInfoDb_1.28.4        
## [19] IRanges_2.26.0              S4Vectors_0.30.0           
## [21] BiocGenerics_0.38.0         reshape2_1.4.4             
## 
## loaded via a namespace (and not attached):
##  [1] colorspace_2.0-3       ellipsis_0.3.2         rprojroot_2.0.2       
##  [4] XVector_0.32.0         rstudioapi_0.13        bit64_4.0.5           
##  [7] AnnotationDbi_1.54.1   fansi_1.0.2            xml2_1.3.3            
## [10] splines_4.2.0          cachem_1.0.6           geneplotter_1.70.0    
## [13] knitr_1.37             jsonlite_1.7.3         annotate_1.70.0       
## [16] png_0.1-7              shiny_1.7.1            compiler_4.2.0        
## [19] httr_1.4.2             assertthat_0.2.1       Matrix_1.4-1          
## [22] fastmap_1.1.0          cli_3.2.0              later_1.3.0           
## [25] htmltools_0.5.2        tools_4.2.0            gtable_0.3.0          
## [28] glue_1.6.1             GenomeInfoDbData_1.2.6 Rcpp_1.0.8            
## [31] jquerylib_0.1.4        vctrs_0.3.8            Biostrings_2.60.2     
## [34] svglite_2.1.0          xfun_0.29              stringr_1.4.0         
## [37] brio_1.1.3             testthat_3.1.2         rvest_1.0.2           
## [40] mime_0.12              lifecycle_1.0.1        XML_3.99-0.8          
## [43] zlibbioc_1.38.0        MASS_7.3-57            scales_1.1.1          
## [46] promises_1.2.0.1       RColorBrewer_1.1-2     yaml_2.3.5            
## [49] memoise_2.0.1          gridExtra_2.3          sass_0.4.0            
## [52] reshape_0.8.8          stringi_1.7.6          RSQLite_2.2.10        
## [55] highr_0.9              genefilter_1.74.0      desc_1.4.0            
## [58] caTools_1.18.2         BiocParallel_1.26.2    rlang_1.0.1           
## [61] pkgconfig_2.0.3        systemfonts_1.0.4      bitops_1.0-7          
## [64] evaluate_0.15          lattice_0.20-45        purrr_0.3.4           
## [67] htmlwidgets_1.5.4      bit_4.0.4              tidyselect_1.1.2      
## [70] plyr_1.8.6             magrittr_2.0.2         R6_2.5.1              
## [73] generics_0.1.2         DelayedArray_0.18.0    DBI_1.1.2             
## [76] pillar_1.7.0           withr_2.4.3            survival_3.2-13       
## [79] KEGGREST_1.32.0        RCurl_1.98-1.6         crayon_1.5.0          
## [82] KernSmooth_2.23-20     utf8_1.2.2             rmarkdown_2.11        
## [85] locfit_1.5-9.4         grid_4.2.0             blob_1.2.2            
## [88] digest_0.6.29          webshot_0.5.2          xtable_1.8-4          
## [91] httpuv_1.6.5           munsell_0.5.0          viridisLite_0.4.0     
## [94] bslib_0.3.1

END of report