Mitch Report

date generated: 2020-12-06

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

##                     x
##           393.8656285
## 5_8S_rRNA   4.2647989
## A1BG       -0.4250025
## A1CF        0.9452369
## A2M        -0.4893072
## A3GALT2    -0.6719394

Here are some metrics about the input data profile:

Profile metrics

	Profile metrics
num_genesets	2408
num_genes_in_profile	18043
duplicated_genes_present	0
num_profile_genes_in_sets	9487
num_profile_genes_not_in_sets	8556

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt

Gene sets metrics

	Gene sets metrics
num_genesets	2408
num_genesets_excluded	960
num_genesets_included	1448

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

set	setSize	pANOVA	s.dist	p.adjustANOVA
Xenobiotics	20	1.64e-07	-0.6760	0.000238
Plasma lipoprotein remodeling	31	1.95e-06	-0.4940	0.001410
Fatty acids	14	4.06e-06	-0.7110	0.001820
Collagen formation	80	5.04e-06	0.2950	0.001820
Collagen biosynthesis and modifying enzymes	58	7.24e-06	0.3410	0.002100
NR1H2 and NR1H3-mediated signaling	48	3.30e-05	-0.3460	0.007970
Phase I - Functionalization of compounds	91	4.09e-05	-0.2490	0.008460
Translation	262	5.52e-05	0.1450	0.009990
Interferon alpha/beta signaling	63	7.04e-05	-0.2900	0.010700
Biological oxidations	176	7.41e-05	-0.1730	0.010700
Assembly of active LPL and LIPC lipase complexes	19	1.16e-04	-0.5110	0.015200
Cell death signalling via NRAGE, NRIF and NADE	72	2.42e-04	-0.2500	0.029200
Cell junction organization	85	3.01e-04	-0.2270	0.031400
Sulfur amino acid metabolism	25	3.03e-04	-0.4170	0.031400
Phenylalanine and tyrosine metabolism	11	3.55e-04	-0.6220	0.033600
Extracellular matrix organization	274	3.72e-04	0.1250	0.033600
Cytochrome P450 - arranged by substrate type	58	4.24e-04	-0.2680	0.036100
p75 NTR receptor-mediated signalling	92	4.71e-04	-0.2110	0.037900
Plasma lipoprotein assembly, remodeling, and clearance	68	5.54e-04	-0.2420	0.040700
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	39	5.62e-04	-0.3190	0.040700
Signal Transduction	2386	7.12e-04	-0.0429	0.049100
Synthesis of substrates in N-glycan biosythesis	61	8.69e-04	0.2470	0.055200
Plasma lipoprotein assembly	18	8.76e-04	-0.4530	0.055200
Death Receptor Signalling	132	1.02e-03	-0.1660	0.061300
Keratan sulfate degradation	12	1.08e-03	0.5450	0.061300
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	75	1.15e-03	0.2170	0.061300
GPCR downstream signalling	829	1.16e-03	-0.0667	0.061300
Miscellaneous substrates	12	1.19e-03	-0.5400	0.061300
Chylomicron remodeling	10	1.25e-03	-0.5890	0.061300
Factors involved in megakaryocyte development and platelet production	124	1.27e-03	-0.1680	0.061300
Endosomal/Vacuolar pathway	10	1.37e-03	-0.5850	0.063500
Platelet Aggregation (Plug Formation)	37	1.43e-03	-0.3030	0.063500
Formation of the beta-catenin:TCF transactivating complex	41	1.45e-03	-0.2880	0.063500
Regulation of lipid metabolism by PPARalpha	116	1.58e-03	-0.1700	0.067400
Keratan sulfate/keratin metabolism	31	1.64e-03	0.3270	0.067700
Intrinsic Pathway of Fibrin Clot Formation	23	1.77e-03	-0.3770	0.068500
Hemostasis	582	1.81e-03	-0.0759	0.068500
Chromatin modifying enzymes	208	1.90e-03	-0.1250	0.068500
Chromatin organization	208	1.90e-03	-0.1250	0.068500
Mitochondrial translation initiation	85	1.93e-03	0.1950	0.068500
Rho GTPase cycle	134	2.01e-03	-0.1550	0.068500
GRB2:SOS provides linkage to MAPK signaling for Integrins	15	2.05e-03	-0.4600	0.068500
Aflatoxin activation and detoxification	18	2.05e-03	-0.4200	0.068500
Formation of Fibrin Clot (Clotting Cascade)	37	2.08e-03	-0.2920	0.068500
Protein ubiquitination	65	2.19e-03	-0.2200	0.069700
Signaling by GPCR	895	2.26e-03	-0.0605	0.069700
Cytosolic tRNA aminoacylation	23	2.26e-03	0.3680	0.069700
p130Cas linkage to MAPK signaling for integrins	15	2.31e-03	-0.4540	0.069700
NRAGE signals death through JNK	56	2.38e-03	-0.2350	0.070400
Influenza Infection	128	2.53e-03	0.1550	0.072500

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
Xenobiotics	20	1.64e-07	-6.76e-01	0.000238
Plasma lipoprotein remodeling	31	1.95e-06	-4.94e-01	0.001410
Fatty acids	14	4.06e-06	-7.11e-01	0.001820
Collagen formation	80	5.04e-06	2.95e-01	0.001820
Collagen biosynthesis and modifying enzymes	58	7.24e-06	3.41e-01	0.002100
NR1H2 and NR1H3-mediated signaling	48	3.30e-05	-3.46e-01	0.007970
Phase I - Functionalization of compounds	91	4.09e-05	-2.49e-01	0.008460
Translation	262	5.52e-05	1.45e-01	0.009990
Interferon alpha/beta signaling	63	7.04e-05	-2.90e-01	0.010700
Biological oxidations	176	7.41e-05	-1.73e-01	0.010700
Assembly of active LPL and LIPC lipase complexes	19	1.16e-04	-5.11e-01	0.015200
Cell death signalling via NRAGE, NRIF and NADE	72	2.42e-04	-2.50e-01	0.029200
Cell junction organization	85	3.01e-04	-2.27e-01	0.031400
Sulfur amino acid metabolism	25	3.03e-04	-4.17e-01	0.031400
Phenylalanine and tyrosine metabolism	11	3.55e-04	-6.22e-01	0.033600
Extracellular matrix organization	274	3.72e-04	1.25e-01	0.033600
Cytochrome P450 - arranged by substrate type	58	4.24e-04	-2.68e-01	0.036100
p75 NTR receptor-mediated signalling	92	4.71e-04	-2.11e-01	0.037900
Plasma lipoprotein assembly, remodeling, and clearance	68	5.54e-04	-2.42e-01	0.040700
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	39	5.62e-04	-3.19e-01	0.040700
Signal Transduction	2386	7.12e-04	-4.29e-02	0.049100
Synthesis of substrates in N-glycan biosythesis	61	8.69e-04	2.47e-01	0.055200
Plasma lipoprotein assembly	18	8.76e-04	-4.53e-01	0.055200
Death Receptor Signalling	132	1.02e-03	-1.66e-01	0.061300
Keratan sulfate degradation	12	1.08e-03	5.45e-01	0.061300
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	75	1.15e-03	2.17e-01	0.061300
GPCR downstream signalling	829	1.16e-03	-6.67e-02	0.061300
Miscellaneous substrates	12	1.19e-03	-5.40e-01	0.061300
Chylomicron remodeling	10	1.25e-03	-5.89e-01	0.061300
Factors involved in megakaryocyte development and platelet production	124	1.27e-03	-1.68e-01	0.061300
Endosomal/Vacuolar pathway	10	1.37e-03	-5.85e-01	0.063500
Platelet Aggregation (Plug Formation)	37	1.43e-03	-3.03e-01	0.063500
Formation of the beta-catenin:TCF transactivating complex	41	1.45e-03	-2.88e-01	0.063500
Regulation of lipid metabolism by PPARalpha	116	1.58e-03	-1.70e-01	0.067400
Keratan sulfate/keratin metabolism	31	1.64e-03	3.27e-01	0.067700
Intrinsic Pathway of Fibrin Clot Formation	23	1.77e-03	-3.77e-01	0.068500
Hemostasis	582	1.81e-03	-7.59e-02	0.068500
Chromatin modifying enzymes	208	1.90e-03	-1.25e-01	0.068500
Chromatin organization	208	1.90e-03	-1.25e-01	0.068500
Mitochondrial translation initiation	85	1.93e-03	1.95e-01	0.068500
Rho GTPase cycle	134	2.01e-03	-1.55e-01	0.068500
GRB2:SOS provides linkage to MAPK signaling for Integrins	15	2.05e-03	-4.60e-01	0.068500
Aflatoxin activation and detoxification	18	2.05e-03	-4.20e-01	0.068500
Formation of Fibrin Clot (Clotting Cascade)	37	2.08e-03	-2.92e-01	0.068500
Protein ubiquitination	65	2.19e-03	-2.20e-01	0.069700
Signaling by GPCR	895	2.26e-03	-6.05e-02	0.069700
Cytosolic tRNA aminoacylation	23	2.26e-03	3.68e-01	0.069700
p130Cas linkage to MAPK signaling for integrins	15	2.31e-03	-4.54e-01	0.069700
NRAGE signals death through JNK	56	2.38e-03	-2.35e-01	0.070400
Influenza Infection	128	2.53e-03	1.55e-01	0.072500
Keratan sulfate biosynthesis	26	2.55e-03	3.42e-01	0.072500
Cell-cell junction organization	60	2.73e-03	-2.24e-01	0.076000
Gluconeogenesis	31	2.99e-03	-3.08e-01	0.081700
PPARA activates gene expression	114	3.05e-03	-1.61e-01	0.081700
Generation of second messenger molecules	28	3.40e-03	-3.20e-01	0.088800
Chylomicron assembly	10	3.44e-03	-5.34e-01	0.088800
Defects in vitamin and cofactor metabolism	22	3.60e-03	-3.59e-01	0.091400
Assembly of collagen fibrils and other multimeric structures	50	3.70e-03	2.37e-01	0.092300
TRAF6 mediated IRF7 activation	26	3.81e-03	-3.28e-01	0.093400
SRP-dependent cotranslational protein targeting to membrane	89	4.19e-03	1.76e-01	0.099600
Crosslinking of collagen fibrils	10	4.20e-03	5.23e-01	0.099600
Viral mRNA Translation	66	4.26e-03	2.03e-01	0.099600
Signaling by NOTCH1	69	4.36e-03	-1.98e-01	0.100000
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	71	4.58e-03	1.95e-01	0.104000
Mitochondrial translation termination	85	4.67e-03	1.78e-01	0.104000
Mitochondrial translation elongation	85	4.75e-03	1.77e-01	0.104000
Major pathway of rRNA processing in the nucleolus and cytosol	157	5.17e-03	1.29e-01	0.112000
rRNA processing in the nucleus and cytosol	166	5.32e-03	1.25e-01	0.112000
Extra-nuclear estrogen signaling	71	5.34e-03	1.91e-01	0.112000
Collagen chain trimerization	35	5.86e-03	2.69e-01	0.121000
Selenoamino acid metabolism	91	5.96e-03	1.67e-01	0.121000
mRNA Splicing - Major Pathway	169	6.02e-03	-1.23e-01	0.121000
Cell-extracellular matrix interactions	16	6.49e-03	-3.93e-01	0.129000
Cell-Cell communication	117	7.04e-03	-1.44e-01	0.136000
mRNA Splicing	177	7.04e-03	-1.18e-01	0.136000
RNA Polymerase III Abortive And Retractive Initiation	37	7.82e-03	-2.53e-01	0.147000
RNA Polymerase III Transcription	37	7.82e-03	-2.53e-01	0.147000
Biotin transport and metabolism	11	8.67e-03	-4.57e-01	0.161000
Intra-Golgi traffic	42	9.18e-03	2.32e-01	0.166000
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS)	16	9.31e-03	-3.76e-01	0.166000
Diseases of hemostasis	16	9.31e-03	-3.76e-01	0.166000
Complement cascade	76	9.57e-03	-1.72e-01	0.169000
Mitochondrial translation	91	9.99e-03	1.56e-01	0.173000
PKA activation in glucagon signalling	16	1.00e-02	-3.72e-01	0.173000
Tight junction interactions	28	1.05e-02	-2.80e-01	0.176000
Peptide chain elongation	66	1.05e-02	1.82e-01	0.176000
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	14	1.07e-02	3.94e-01	0.179000
Respiratory electron transport	95	1.10e-02	1.51e-01	0.181000
Response of EIF2AK4 (GCN2) to amino acid deficiency	78	1.11e-02	1.66e-01	0.181000
Defensins	27	1.13e-02	-2.82e-01	0.182000
Activated NOTCH1 Transmits Signal to the Nucleus	30	1.15e-02	-2.67e-01	0.182000
E3 ubiquitin ligases ubiquitinate target proteins	46	1.19e-02	-2.14e-01	0.188000
Myogenesis	29	1.24e-02	-2.68e-01	0.193000
Zinc influx into cells by the SLC39 gene family	10	1.28e-02	4.55e-01	0.197000
Eukaryotic Translation Elongation	70	1.31e-02	1.71e-01	0.200000
Eukaryotic Translation Termination	70	1.35e-02	1.71e-01	0.202000
tRNA processing in the mitochondrion	18	1.36e-02	-3.36e-01	0.202000
DARPP-32 events	23	1.44e-02	-2.95e-01	0.213000
Elastic fibre formation	38	1.47e-02	2.29e-01	0.214000
Signaling by NOTCH	184	1.60e-02	-1.03e-01	0.230000
Complex I biogenesis	53	1.60e-02	1.91e-01	0.230000
Activation of HOX genes during differentiation	67	1.68e-02	-1.69e-01	0.237000
Activation of anterior HOX genes in hindbrain development during early embryogenesis	67	1.68e-02	-1.69e-01	0.237000
Signaling by Insulin receptor	76	1.75e-02	1.58e-01	0.244000
tRNA Aminoacylation	41	1.78e-02	2.14e-01	0.246000
Metabolism of lipids	692	1.83e-02	-5.28e-02	0.250000
Regulation of IFNA signaling	24	1.85e-02	-2.78e-01	0.250000
IL-6-type cytokine receptor ligand interactions	17	1.89e-02	-3.29e-01	0.251000
LDL clearance	18	1.97e-02	3.17e-01	0.251000
Antimicrobial peptides	58	1.99e-02	-1.77e-01	0.251000
Influenza Viral RNA Transcription and Replication	109	2.01e-02	1.29e-01	0.251000
Asparagine N-linked glycosylation	268	2.01e-02	8.26e-02	0.251000
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	116	2.03e-02	1.25e-01	0.251000
Pausing and recovery of Tat-mediated HIV elongation	32	2.03e-02	-2.37e-01	0.251000
Tat-mediated HIV elongation arrest and recovery	32	2.03e-02	-2.37e-01	0.251000
Peptide ligand-binding receptors	161	2.03e-02	-1.06e-01	0.251000
Glycosaminoglycan metabolism	117	2.03e-02	1.24e-01	0.251000
PI-3K cascade:FGFR3	18	2.05e-02	3.15e-01	0.252000
Developmental Biology	905	2.12e-02	-4.54e-02	0.258000
Oncogenic MAPK signaling	77	2.21e-02	-1.51e-01	0.267000
Synthesis of PC	28	2.30e-02	-2.48e-01	0.276000
FGFR3 mutant receptor activation	12	2.39e-02	3.77e-01	0.282000
Signaling by activated point mutants of FGFR3	12	2.39e-02	3.77e-01	0.282000
Downstream signaling of activated FGFR3	25	2.45e-02	2.60e-01	0.286000
RNA Polymerase III Transcription Termination	19	2.63e-02	-2.95e-01	0.302000
Selenocysteine synthesis	69	2.63e-02	1.55e-01	0.302000
Signaling by NTRK3 (TRKC)	17	2.65e-02	3.11e-01	0.302000
Glyoxylate metabolism and glycine degradation	30	2.69e-02	-2.33e-01	0.303000
Formation of the cornified envelope	39	2.71e-02	-2.05e-01	0.303000
FGFR3 ligand binding and activation	13	2.74e-02	3.53e-01	0.303000
FGFR3c ligand binding and activation	13	2.74e-02	3.53e-01	0.303000
Sialic acid metabolism	32	2.86e-02	2.24e-01	0.314000
Integrin signaling	27	2.92e-02	-2.42e-01	0.317000
Regulated proteolysis of p75NTR	11	2.93e-02	-3.79e-01	0.317000
SHC-mediated cascade:FGFR3	18	2.98e-02	2.96e-01	0.320000
Semaphorin interactions	63	3.02e-02	-1.58e-01	0.321000
PKA activation	16	3.04e-02	-3.13e-01	0.321000
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	52	3.08e-02	1.73e-01	0.323000
Other interleukin signaling	22	3.14e-02	-2.65e-01	0.327000
Immune System	1931	3.22e-02	-2.98e-02	0.333000
RAF-independent MAPK1/3 activation	23	3.24e-02	-2.58e-01	0.333000
RA biosynthesis pathway	18	3.26e-02	2.91e-01	0.333000
Signaling by BRAF and RAF fusions	61	3.29e-02	-1.58e-01	0.333000
Synthesis of IP2, IP, and Ins in the cytosol	14	3.31e-02	3.29e-01	0.333000
Diseases of DNA repair	10	3.35e-02	3.88e-01	0.334000
Transferrin endocytosis and recycling	29	3.37e-02	2.28e-01	0.334000
Neurotransmitter clearance	10	3.39e-02	-3.87e-01	0.334000
Downregulation of TGF-beta receptor signaling	25	3.44e-02	2.44e-01	0.337000
Eicosanoids	12	3.55e-02	-3.51e-01	0.345000
HIV elongation arrest and recovery	34	3.65e-02	-2.07e-01	0.350000
Pausing and recovery of HIV elongation	34	3.65e-02	-2.07e-01	0.350000
Role of second messengers in netrin-1 signaling	10	3.69e-02	3.81e-01	0.351000
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	27	3.72e-02	-2.32e-01	0.352000
Interleukin-6 family signaling	24	3.75e-02	-2.45e-01	0.352000
Regulation of cholesterol biosynthesis by SREBP (SREBF)	53	3.80e-02	-1.65e-01	0.354000
Synthesis of PIPs at the late endosome membrane	11	3.81e-02	3.61e-01	0.354000
Metabolism of proteins	1819	3.84e-02	2.96e-02	0.354000
Activation of SMO	18	3.94e-02	2.81e-01	0.361000
IGF1R signaling cascade	51	4.05e-02	1.66e-01	0.366000
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	90	4.11e-02	1.25e-01	0.366000
Nonsense-Mediated Decay (NMD)	90	4.11e-02	1.25e-01	0.366000
Vasopressin regulates renal water homeostasis via Aquaporins	41	4.11e-02	-1.84e-01	0.366000
Activation of gene expression by SREBF (SREBP)	41	4.12e-02	-1.84e-01	0.366000
Retinoid metabolism and transport	39	4.18e-02	-1.88e-01	0.368000
Class I peroxisomal membrane protein import	18	4.21e-02	-2.77e-01	0.368000
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	13	4.21e-02	3.26e-01	0.368000
Dermatan sulfate biosynthesis	11	4.37e-02	3.51e-01	0.375000
rRNA processing	187	4.41e-02	8.54e-02	0.375000
L13a-mediated translational silencing of Ceruloplasmin expression	85	4.42e-02	1.26e-01	0.375000
G alpha (i) signalling events	350	4.51e-02	-6.24e-02	0.375000
Recycling of bile acids and salts	15	4.51e-02	-2.99e-01	0.375000
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	54	4.58e-02	-1.57e-01	0.375000
Constitutive Signaling by NOTCH1 PEST Domain Mutants	54	4.58e-02	-1.57e-01	0.375000
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	54	4.58e-02	-1.57e-01	0.375000
Signaling by NOTCH1 PEST Domain Mutants in Cancer	54	4.58e-02	-1.57e-01	0.375000
Signaling by NOTCH1 in Cancer	54	4.58e-02	-1.57e-01	0.375000
Regulation of expression of SLITs and ROBOs	145	4.59e-02	9.61e-02	0.375000
Transcription-Coupled Nucleotide Excision Repair (TC-NER)	74	4.64e-02	-1.34e-01	0.375000
Kinesins	40	4.65e-02	-1.82e-01	0.375000
Hedgehog 'on' state	83	4.67e-02	1.26e-01	0.375000
GTP hydrolysis and joining of the 60S ribosomal subunit	87	4.69e-02	1.23e-01	0.375000
DNA Damage Recognition in GG-NER	37	4.71e-02	-1.89e-01	0.375000
Transcriptional regulation by RUNX3	88	4.87e-02	-1.22e-01	0.385000
Endosomal Sorting Complex Required For Transport (ESCRT)	29	4.97e-02	-2.11e-01	0.390000
Nucleotide Excision Repair	106	4.98e-02	-1.10e-01	0.390000
Formation of a pool of free 40S subunits	77	5.09e-02	1.29e-01	0.393000
Aquaporin-mediated transport	49	5.11e-02	-1.61e-01	0.393000
Cap-dependent Translation Initiation	93	5.13e-02	1.17e-01	0.393000
Eukaryotic Translation Initiation	93	5.13e-02	1.17e-01	0.393000
Transcriptional regulation of white adipocyte differentiation	81	5.16e-02	-1.25e-01	0.393000
RHO GTPases activate PAKs	21	5.20e-02	-2.45e-01	0.394000
RMTs methylate histone arginines	36	5.32e-02	-1.86e-01	0.402000
Synthesis of Leukotrienes (LT) and Eoxins (EX)	21	5.36e-02	-2.43e-01	0.402000
FRS-mediated FGFR3 signaling	20	5.43e-02	2.49e-01	0.406000
FOXO-mediated transcription	64	5.50e-02	-1.39e-01	0.409000
Signaling by NOTCH3	44	5.63e-02	-1.66e-01	0.414000
Translocation of ZAP-70 to Immunological synapse	14	5.66e-02	-2.94e-01	0.414000
NS1 Mediated Effects on Host Pathways	40	5.67e-02	1.74e-01	0.414000
Neuronal System	375	5.72e-02	-5.73e-02	0.416000
Vitamin D (calciferol) metabolism	11	5.74e-02	-3.31e-01	0.416000
Phospholipase C-mediated cascade; FGFR3	13	5.82e-02	3.03e-01	0.418000
Diseases of glycosylation	134	5.84e-02	9.48e-02	0.418000
Mitotic Metaphase and Anaphase	219	5.91e-02	7.41e-02	0.420000
Postmitotic nuclear pore complex (NPC) reformation	26	5.92e-02	2.14e-01	0.420000
Sema4D induced cell migration and growth-cone collapse	20	5.99e-02	-2.43e-01	0.423000
Keratinization	123	6.01e-02	9.82e-02	0.423000
Diseases associated with glycosaminoglycan metabolism	39	6.08e-02	1.74e-01	0.425000
Notch-HLH transcription pathway	26	6.18e-02	-2.12e-01	0.430000
FOXO-mediated transcription of cell death genes	14	6.22e-02	-2.88e-01	0.430000
Transcriptional regulation of pluripotent stem cells	29	6.29e-02	-2.00e-01	0.430000
IRS-related events triggered by IGF1R	50	6.30e-02	1.52e-01	0.430000
Pre-NOTCH Processing in Golgi	18	6.31e-02	-2.53e-01	0.430000
Metabolism	1943	6.32e-02	-2.58e-02	0.430000
Molecules associated with elastic fibres	28	6.38e-02	2.02e-01	0.431000
Iron uptake and transport	54	6.40e-02	1.46e-01	0.431000
Sema4D in semaphorin signaling	24	6.44e-02	-2.18e-01	0.431000
Signaling by FGFR3 in disease	22	6.51e-02	2.27e-01	0.431000
Signaling by FGFR3 point mutants in cancer	22	6.51e-02	2.27e-01	0.431000
Processing of Capped Intron-Containing Pre-mRNA	228	6.52e-02	-7.09e-02	0.431000
RNA Polymerase III Transcription Initiation From Type 3 Promoter	24	6.57e-02	-2.17e-01	0.432000
Regulation of beta-cell development	39	6.62e-02	-1.70e-01	0.434000
The citric acid (TCA) cycle and respiratory electron transport	165	6.70e-02	8.27e-02	0.437000
Zinc transporters	17	6.75e-02	2.56e-01	0.438000
Mitotic Anaphase	218	6.78e-02	7.18e-02	0.438000
rRNA processing in the mitochondrion	21	6.80e-02	-2.30e-01	0.438000
Cobalamin (Cbl, vitamin B12) transport and metabolism	20	6.96e-02	-2.34e-01	0.443000
Mitochondrial protein import	62	7.00e-02	1.33e-01	0.443000
ROS and RNS production in phagocytes	34	7.01e-02	1.80e-01	0.443000
IRS-mediated signalling	47	7.07e-02	1.52e-01	0.443000
PI3K Cascade	43	7.08e-02	1.59e-01	0.443000
Synthesis of PIPs at the Golgi membrane	17	7.09e-02	2.53e-01	0.443000
MAPK3 (ERK1) activation	10	7.13e-02	-3.29e-01	0.443000
Mitochondrial iron-sulfur cluster biogenesis	11	7.13e-02	3.14e-01	0.443000
Listeria monocytogenes entry into host cells	19	7.16e-02	-2.39e-01	0.443000
Diseases of carbohydrate metabolism	32	7.33e-02	-1.83e-01	0.452000
Regulation of TP53 Activity through Acetylation	28	7.36e-02	-1.95e-01	0.452000
ERBB2 Regulates Cell Motility	15	7.41e-02	2.66e-01	0.453000
Defects in cobalamin (B12) metabolism	14	7.48e-02	-2.75e-01	0.455000
Innate Immune System	964	7.69e-02	-3.38e-02	0.466000
PD-1 signaling	19	7.89e-02	-2.33e-01	0.474000
NOTCH4 Activation and Transmission of Signal to the Nucleus	11	7.90e-02	-3.06e-01	0.474000
cGMP effects	15	7.96e-02	-2.61e-01	0.476000
Glutathione conjugation	30	8.04e-02	-1.84e-01	0.478000
Late endosomal microautophagy	30	8.06e-02	-1.84e-01	0.478000
Diseases associated with the TLR signaling cascade	20	8.28e-02	2.24e-01	0.488000
Diseases of Immune System	20	8.28e-02	2.24e-01	0.488000
RIP-mediated NFkB activation via ZBP1	15	8.50e-02	2.57e-01	0.496000
Downstream signaling of activated FGFR2	30	8.50e-02	1.82e-01	0.496000
Metabolism of steroids	133	8.61e-02	-8.62e-02	0.497000
Synthesis of PIPs at the early endosome membrane	16	8.61e-02	2.48e-01	0.497000
Class A/1 (Rhodopsin-like receptors)	280	8.64e-02	-5.96e-02	0.497000
Membrane binding and targetting of GAG proteins	13	8.70e-02	-2.74e-01	0.497000
Synthesis And Processing Of GAG, GAGPOL Polyproteins	13	8.70e-02	-2.74e-01	0.497000
Metabolism of fat-soluble vitamins	43	8.71e-02	-1.51e-01	0.497000
Metabolism of folate and pterines	17	8.91e-02	-2.38e-01	0.506000
G alpha (s) signalling events	322	9.00e-02	-5.50e-02	0.507000
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	20	9.03e-02	-2.19e-01	0.507000
O-linked glycosylation of mucins	55	9.05e-02	1.32e-01	0.507000
NOTCH1 Intracellular Domain Regulates Transcription	43	9.08e-02	-1.49e-01	0.507000
L1CAM interactions	98	9.19e-02	-9.86e-02	0.509000
Tandem pore domain potassium channels	11	9.32e-02	-2.92e-01	0.509000
Degradation of cysteine and homocysteine	11	9.34e-02	-2.92e-01	0.509000
Metabolism of nucleotides	95	9.35e-02	9.96e-02	0.509000
PI-3K cascade:FGFR2	23	9.47e-02	2.01e-01	0.509000
HIV Transcription Initiation	42	9.48e-02	1.49e-01	0.509000
RNA Polymerase II HIV Promoter Escape	42	9.48e-02	1.49e-01	0.509000
RNA Polymerase II Promoter Escape	42	9.48e-02	1.49e-01	0.509000
RNA Polymerase II Transcription Initiation	42	9.48e-02	1.49e-01	0.509000
RNA Polymerase II Transcription Initiation And Promoter Clearance	42	9.48e-02	1.49e-01	0.509000
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	42	9.48e-02	1.49e-01	0.509000
GP1b-IX-V activation signalling	10	1.02e-01	-2.99e-01	0.537000
TNFR1-induced proapoptotic signaling	13	1.03e-01	-2.61e-01	0.537000
Paradoxical activation of RAF signaling by kinase inactive BRAF	41	1.03e-01	-1.47e-01	0.537000
Signaling by RAS mutants	41	1.03e-01	-1.47e-01	0.537000
Signaling by moderate kinase activity BRAF mutants	41	1.03e-01	-1.47e-01	0.537000
Signaling downstream of RAS mutants	41	1.03e-01	-1.47e-01	0.537000
Formation of RNA Pol II elongation complex	59	1.04e-01	-1.23e-01	0.537000
RNA Polymerase II Transcription Elongation	59	1.04e-01	-1.23e-01	0.537000
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	29	1.04e-01	-1.75e-01	0.537000
Translation of structural proteins	27	1.04e-01	-1.81e-01	0.537000
Downstream signaling of activated FGFR1	31	1.04e-01	1.69e-01	0.537000
Negative regulation of MAPK pathway	42	1.05e-01	-1.44e-01	0.541000
Activation of the pre-replicative complex	32	1.07e-01	1.65e-01	0.545000
Insulin receptor signalling cascade	53	1.08e-01	1.28e-01	0.550000
PI3K events in ERBB2 signaling	16	1.09e-01	2.32e-01	0.551000
NOTCH3 Activation and Transmission of Signal to the Nucleus	23	1.09e-01	-1.93e-01	0.551000
NOTCH2 Activation and Transmission of Signal to the Nucleus	20	1.10e-01	-2.07e-01	0.552000
Interferon Signaling	177	1.10e-01	-6.97e-02	0.552000
Glutamate binding, activation of AMPA receptors and synaptic plasticity	30	1.11e-01	-1.68e-01	0.553000
Trafficking of AMPA receptors	30	1.11e-01	-1.68e-01	0.553000
ESR-mediated signaling	164	1.11e-01	7.21e-02	0.554000
Adenylate cyclase inhibitory pathway	14	1.12e-01	-2.45e-01	0.556000
Smooth Muscle Contraction	33	1.13e-01	-1.60e-01	0.556000
Chondroitin sulfate biosynthesis	20	1.13e-01	2.05e-01	0.557000
Transcriptional regulation by RUNX2	117	1.13e-01	8.48e-02	0.557000
Signaling by NTRK2 (TRKB)	25	1.15e-01	1.82e-01	0.562000
Reversible hydration of carbon dioxide	12	1.16e-01	-2.62e-01	0.562000
Metal ion SLC transporters	26	1.16e-01	1.78e-01	0.562000
HATs acetylate histones	84	1.16e-01	-9.92e-02	0.562000
PI3K events in ERBB4 signaling	10	1.17e-01	2.86e-01	0.562000
Transport of organic anions	12	1.17e-01	-2.61e-01	0.562000
Prolactin receptor signaling	15	1.18e-01	-2.33e-01	0.562000
ER Quality Control Compartment (ERQC)	19	1.18e-01	2.07e-01	0.562000
RNA Polymerase III Transcription Initiation	32	1.18e-01	-1.60e-01	0.562000
ERK/MAPK targets	21	1.19e-01	-1.97e-01	0.562000
Formation of TC-NER Pre-Incision Complex	50	1.19e-01	-1.28e-01	0.562000
RHO GTPases Activate ROCKs	19	1.19e-01	-2.06e-01	0.562000
RHO GTPases Activate NADPH Oxidases	23	1.20e-01	1.87e-01	0.565000
Signaling by Rho GTPases	373	1.21e-01	-4.69e-02	0.566000
PKMTs methylate histone lysines	43	1.21e-01	-1.37e-01	0.566000
Pre-NOTCH Expression and Processing	64	1.23e-01	-1.12e-01	0.570000
SHC-mediated cascade:FGFR2	23	1.23e-01	1.86e-01	0.570000
TGF-beta receptor signaling activates SMADs	30	1.25e-01	1.62e-01	0.578000
Hyaluronan metabolism	17	1.26e-01	2.14e-01	0.581000
Striated Muscle Contraction	34	1.26e-01	-1.51e-01	0.581000
Nucleobase catabolism	36	1.27e-01	1.47e-01	0.581000
Common Pathway of Fibrin Clot Formation	20	1.28e-01	-1.97e-01	0.583000
Chemokine receptors bind chemokines	42	1.28e-01	-1.36e-01	0.583000
DNA Replication Pre-Initiation	82	1.29e-01	9.71e-02	0.583000
Global Genome Nucleotide Excision Repair (GG-NER)	82	1.29e-01	-9.70e-02	0.583000
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	22	1.30e-01	-1.87e-01	0.585000
Base-Excision Repair, AP Site Formation	27	1.30e-01	1.68e-01	0.585000
Regulation of gene expression by Hypoxia-inducible Factor	11	1.31e-01	-2.63e-01	0.585000
Metabolism of cofactors	18	1.31e-01	2.05e-01	0.585000
Deposition of new CENPA-containing nucleosomes at the centromere	35	1.32e-01	1.47e-01	0.585000
Nucleosome assembly	35	1.32e-01	1.47e-01	0.585000
Regulation of Complement cascade	68	1.32e-01	-1.06e-01	0.586000
Insulin receptor recycling	25	1.33e-01	1.73e-01	0.589000
Signal transduction by L1	21	1.34e-01	-1.89e-01	0.590000
Budding and maturation of HIV virion	25	1.35e-01	-1.73e-01	0.590000
RUNX2 regulates osteoblast differentiation	24	1.35e-01	1.76e-01	0.590000
Cleavage of the damaged pyrimidine	25	1.36e-01	1.72e-01	0.590000
Depyrimidination	25	1.36e-01	1.72e-01	0.590000
Recognition and association of DNA glycosylase with site containing an affected pyrimidine	25	1.36e-01	1.72e-01	0.590000
mRNA decay by 5' to 3' exoribonuclease	15	1.38e-01	-2.21e-01	0.593000
Interleukin-2 signaling	12	1.38e-01	-2.47e-01	0.593000
tRNA processing in the nucleus	57	1.38e-01	1.13e-01	0.593000
Phase 4 - resting membrane potential	18	1.41e-01	-2.01e-01	0.593000
Adenylate cyclase activating pathway	10	1.43e-01	-2.68e-01	0.593000
Assembly Of The HIV Virion	15	1.43e-01	-2.19e-01	0.593000
Regulation of gene expression in beta cells	21	1.43e-01	-1.85e-01	0.593000
Uptake and actions of bacterial toxins	26	1.43e-01	-1.66e-01	0.593000
Resolution of D-loop Structures through Holliday Junction Intermediates	32	1.43e-01	1.50e-01	0.593000
FGFR2 ligand binding and activation	19	1.44e-01	1.94e-01	0.593000
ECM proteoglycans	53	1.44e-01	1.16e-01	0.593000
FGFR1c ligand binding and activation	11	1.45e-01	2.54e-01	0.593000
Signaling by activated point mutants of FGFR1	11	1.45e-01	2.54e-01	0.593000
Dual incision in TC-NER	61	1.45e-01	-1.08e-01	0.593000
FGFRL1 modulation of FGFR1 signaling	13	1.45e-01	2.33e-01	0.593000
Activated point mutants of FGFR2	17	1.45e-01	2.04e-01	0.593000
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism	12	1.45e-01	-2.43e-01	0.593000
alpha-linolenic acid (ALA) metabolism	12	1.45e-01	-2.43e-01	0.593000
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	46	1.45e-01	-1.24e-01	0.593000
Regulation of IFNG signaling	14	1.46e-01	2.25e-01	0.593000
Pexophagy	10	1.46e-01	-2.66e-01	0.593000
Transmission across Chemical Synapses	241	1.46e-01	-5.44e-02	0.593000
Repression of WNT target genes	14	1.46e-01	-2.24e-01	0.593000
Signaling by ERBB2 in Cancer	24	1.47e-01	1.71e-01	0.593000
Signaling by RAF1 mutants	38	1.48e-01	-1.36e-01	0.594000
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	37	1.48e-01	-1.37e-01	0.594000
Selective autophagy	56	1.48e-01	-1.12e-01	0.594000
EGR2 and SOX10-mediated initiation of Schwann cell myelination	26	1.49e-01	-1.64e-01	0.595000
Peroxisomal protein import	60	1.51e-01	-1.07e-01	0.602000
Adherens junctions interactions	31	1.53e-01	-1.48e-01	0.607000
Regulation of TP53 Activity through Phosphorylation	84	1.54e-01	9.00e-02	0.608000
Killing mechanisms	12	1.54e-01	2.38e-01	0.608000
WNT5:FZD7-mediated leishmania damping	12	1.54e-01	2.38e-01	0.608000
Formation of the ternary complex, and subsequently, the 43S complex	44	1.55e-01	1.24e-01	0.611000
Muscle contraction	177	1.56e-01	-6.18e-02	0.613000
Dual Incision in GG-NER	39	1.57e-01	-1.31e-01	0.615000
PKA-mediated phosphorylation of CREB	18	1.59e-01	-1.92e-01	0.620000
O-linked glycosylation	102	1.59e-01	8.07e-02	0.620000
Fc epsilon receptor (FCERI) signaling	153	1.61e-01	6.57e-02	0.626000
Chaperone Mediated Autophagy	18	1.63e-01	-1.90e-01	0.629000
FCERI mediated MAPK activation	56	1.63e-01	1.08e-01	0.631000
Nuclear Events (kinase and transcription factor activation)	60	1.67e-01	-1.03e-01	0.642000
BMAL1:CLOCK,NPAS2 activates circadian gene expression	27	1.68e-01	-1.53e-01	0.643000
Ribosomal scanning and start codon recognition	50	1.68e-01	1.13e-01	0.643000
PRC2 methylates histones and DNA	23	1.71e-01	-1.65e-01	0.649000
Metabolism of vitamins and cofactors	179	1.71e-01	-5.94e-02	0.649000
ZBP1(DAI) mediated induction of type I IFNs	19	1.71e-01	1.81e-01	0.649000
Establishment of Sister Chromatid Cohesion	11	1.72e-01	2.38e-01	0.649000
Signaling by TGFB family members	96	1.72e-01	8.06e-02	0.649000
Regulation of TLR by endogenous ligand	15	1.73e-01	-2.03e-01	0.649000
COPII-mediated vesicle transport	61	1.73e-01	-1.01e-01	0.649000
G alpha (12/13) signalling events	76	1.73e-01	-9.03e-02	0.649000
Mucopolysaccharidoses	11	1.74e-01	-2.37e-01	0.649000
Interactions of Rev with host cellular proteins	36	1.74e-01	1.31e-01	0.649000
FRS-mediated FGFR2 signaling	25	1.74e-01	1.57e-01	0.649000
DAG and IP3 signaling	38	1.75e-01	-1.27e-01	0.649000
Initial triggering of complement	45	1.75e-01	-1.17e-01	0.649000
Effects of PIP2 hydrolysis	27	1.76e-01	-1.50e-01	0.649000
Activated NTRK2 signals through FRS2 and FRS3	11	1.76e-01	2.36e-01	0.649000
Signaling by Leptin	11	1.77e-01	-2.35e-01	0.649000
M Phase	347	1.78e-01	4.22e-02	0.650000
Separation of Sister Chromatids	166	1.78e-01	6.06e-02	0.650000
AKT phosphorylates targets in the cytosol	14	1.78e-01	-2.08e-01	0.650000
EML4 and NUDC in mitotic spindle formation	95	1.79e-01	7.99e-02	0.650000
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	12	1.79e-01	-2.24e-01	0.651000
G beta:gamma signalling through BTK	17	1.80e-01	1.88e-01	0.651000
Receptor Mediated Mitophagy	11	1.80e-01	-2.33e-01	0.651000
N-glycan antennae elongation in the medial/trans-Golgi	23	1.82e-01	1.61e-01	0.655000
Assembly of the pre-replicative complex	66	1.83e-01	9.49e-02	0.655000
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)	13	1.83e-01	2.13e-01	0.655000
G1/S Transition	127	1.85e-01	6.81e-02	0.663000
Epigenetic regulation of gene expression	94	1.87e-01	-7.89e-02	0.665000
SHC1 events in ERBB2 signaling	22	1.87e-01	1.62e-01	0.666000
Integration of energy metabolism	102	1.88e-01	-7.56e-02	0.666000
Transport of the SLBP Dependant Mature mRNA	35	1.89e-01	1.28e-01	0.667000
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	14	1.89e-01	-2.03e-01	0.667000
Transport of the SLBP independent Mature mRNA	34	1.89e-01	1.30e-01	0.667000
Folding of actin by CCT/TriC	10	1.90e-01	-2.39e-01	0.667000
Mitophagy	26	1.90e-01	-1.48e-01	0.667000
Activation of the AP-1 family of transcription factors	10	1.92e-01	2.38e-01	0.671000
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	23	1.92e-01	1.57e-01	0.671000
Carnitine metabolism	11	1.93e-01	-2.27e-01	0.671000
MECP2 regulates neuronal receptors and channels	16	1.93e-01	1.88e-01	0.671000
TP53 Regulates Transcription of DNA Repair Genes	61	1.94e-01	-9.63e-02	0.671000
Syndecan interactions	19	1.96e-01	1.72e-01	0.674000
Translation initiation complex formation	49	1.96e-01	1.07e-01	0.674000
Resolution of D-Loop Structures	33	1.96e-01	1.30e-01	0.674000
Glucagon signaling in metabolic regulation	30	1.96e-01	-1.36e-01	0.674000
G-protein mediated events	51	1.98e-01	-1.04e-01	0.677000
FGFR2c ligand binding and activation	13	1.98e-01	2.06e-01	0.677000
Downstream signaling of activated FGFR4	26	2.00e-01	1.45e-01	0.682000
Sphingolipid de novo biosynthesis	43	2.01e-01	-1.13e-01	0.683000
HuR (ELAVL1) binds and stabilizes mRNA	10	2.02e-01	-2.33e-01	0.683000
NOTCH3 Intracellular Domain Regulates Transcription	22	2.03e-01	-1.57e-01	0.683000
Nuclear import of Rev protein	33	2.04e-01	1.28e-01	0.683000
SHC1 events in ERBB4 signaling	14	2.04e-01	1.96e-01	0.683000
Cell Cycle, Mitotic	485	2.04e-01	3.38e-02	0.683000
Interleukin-10 signaling	38	2.04e-01	-1.19e-01	0.683000
Phase II - Conjugation of compounds	79	2.04e-01	-8.26e-02	0.683000
Diseases of signal transduction by growth factor receptors and second messengers	367	2.06e-01	-3.85e-02	0.685000
Cell Cycle Checkpoints	252	2.06e-01	4.63e-02	0.685000
Post-chaperonin tubulin folding pathway	18	2.06e-01	1.72e-01	0.685000
Signaling by ERBB2	47	2.07e-01	1.06e-01	0.687000
Asymmetric localization of PCP proteins	62	2.08e-01	9.25e-02	0.688000
The role of Nef in HIV-1 replication and disease pathogenesis	27	2.11e-01	-1.39e-01	0.693000
Cristae formation	27	2.11e-01	1.39e-01	0.693000
Nitric oxide stimulates guanylate cyclase	19	2.12e-01	-1.66e-01	0.695000
Costimulation by the CD28 family	65	2.13e-01	-8.93e-02	0.695000
N-Glycan antennae elongation	14	2.13e-01	1.92e-01	0.695000
Resolution of Sister Chromatid Cohesion	103	2.14e-01	7.09e-02	0.695000
Collagen degradation	37	2.14e-01	1.18e-01	0.695000
Calnexin/calreticulin cycle	24	2.14e-01	1.46e-01	0.695000
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	24	2.15e-01	-1.46e-01	0.695000
PI-3K cascade:FGFR1	21	2.16e-01	1.56e-01	0.695000
Nephrin family interactions	21	2.17e-01	1.56e-01	0.695000
Beta defensins	18	2.17e-01	-1.68e-01	0.695000
CaM pathway	32	2.18e-01	-1.26e-01	0.695000
Calmodulin induced events	32	2.18e-01	-1.26e-01	0.695000
Transport of Mature mRNA derived from an Intron-Containing Transcript	72	2.19e-01	8.38e-02	0.695000
Recognition of DNA damage by PCNA-containing replication complex	28	2.19e-01	-1.34e-01	0.695000
PCP/CE pathway	90	2.20e-01	7.48e-02	0.695000
Interactions of Vpr with host cellular proteins	34	2.20e-01	1.21e-01	0.695000
SLC transporter disorders	96	2.21e-01	7.23e-02	0.695000
Disorders of transmembrane transporters	171	2.22e-01	5.42e-02	0.695000
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	91	2.23e-01	7.39e-02	0.695000
Amplification of signal from the kinetochores	91	2.23e-01	7.39e-02	0.695000
Signaling by FGFR in disease	60	2.23e-01	9.10e-02	0.695000
Formation of HIV-1 elongation complex containing HIV-1 Tat	44	2.23e-01	-1.06e-01	0.695000
HIV Transcription Elongation	44	2.23e-01	-1.06e-01	0.695000
Tat-mediated elongation of the HIV-1 transcript	44	2.23e-01	-1.06e-01	0.695000
Vitamin B5 (pantothenate) metabolism	15	2.24e-01	1.81e-01	0.695000
ABC-family proteins mediated transport	98	2.24e-01	7.11e-02	0.695000
Signaling by ERBB2 KD Mutants	23	2.24e-01	1.46e-01	0.695000
Adrenaline,noradrenaline inhibits insulin secretion	27	2.25e-01	1.35e-01	0.695000
Rev-mediated nuclear export of HIV RNA	34	2.25e-01	1.20e-01	0.695000
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	30	2.28e-01	1.27e-01	0.699000
DDX58/IFIH1-mediated induction of interferon-alpha/beta	68	2.28e-01	-8.45e-02	0.699000
RHO GTPases activate CIT	19	2.28e-01	-1.60e-01	0.699000
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	14	2.28e-01	-1.86e-01	0.699000
NRIF signals cell death from the nucleus	15	2.29e-01	-1.80e-01	0.699000
TICAM1, RIP1-mediated IKK complex recruitment	16	2.30e-01	1.73e-01	0.702000
GRB2 events in ERBB2 signaling	16	2.31e-01	1.73e-01	0.702000
FGFR1 mutant receptor activation	30	2.32e-01	1.26e-01	0.702000
O-glycosylation of TSR domain-containing proteins	37	2.32e-01	1.14e-01	0.702000
PERK regulates gene expression	31	2.32e-01	1.24e-01	0.702000
Signaling by FGFR3	38	2.33e-01	1.12e-01	0.702000
Circadian Clock	68	2.33e-01	-8.36e-02	0.702000
DNA Damage Bypass	44	2.34e-01	-1.04e-01	0.702000
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	26	2.35e-01	1.35e-01	0.702000
p75NTR signals via NF-kB	14	2.35e-01	-1.83e-01	0.702000
Signaling by TGF-beta Receptor Complex	69	2.36e-01	8.25e-02	0.704000
Phospholipase C-mediated cascade; FGFR2	18	2.37e-01	1.61e-01	0.704000
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	17	2.38e-01	1.65e-01	0.704000
Other semaphorin interactions	19	2.38e-01	-1.56e-01	0.704000
Activation of BH3-only proteins	27	2.39e-01	-1.31e-01	0.704000
Metabolism of water-soluble vitamins and cofactors	119	2.39e-01	-6.25e-02	0.704000
FGFR2 mutant receptor activation	31	2.40e-01	1.22e-01	0.704000
Potential therapeutics for SARS	76	2.40e-01	-7.80e-02	0.704000
KSRP (KHSRP) binds and destabilizes mRNA	17	2.40e-01	1.65e-01	0.704000
PI-3K cascade:FGFR4	19	2.41e-01	1.56e-01	0.704000
SUMOylation of chromatin organization proteins	56	2.41e-01	9.06e-02	0.704000
Translesion synthesis by REV1	15	2.41e-01	-1.75e-01	0.704000
CDT1 association with the CDC6:ORC:origin complex	57	2.43e-01	8.95e-02	0.707000
Signaling by NOTCH2	29	2.44e-01	-1.25e-01	0.710000
Maturation of nucleoprotein	10	2.45e-01	-2.12e-01	0.711000
DCC mediated attractive signaling	14	2.48e-01	-1.78e-01	0.717000
Interleukin-1 family signaling	131	2.48e-01	5.84e-02	0.717000
Nuclear signaling by ERBB4	30	2.49e-01	-1.22e-01	0.717000
Signaling by FGFR2 in disease	41	2.49e-01	1.04e-01	0.717000
Aspartate and asparagine metabolism	10	2.49e-01	2.10e-01	0.717000
WNT5A-dependent internalization of FZD4	15	2.50e-01	1.71e-01	0.718000
Translesion Synthesis by POLH	16	2.52e-01	-1.65e-01	0.721000
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	17	2.53e-01	1.60e-01	0.721000
GPCR ligand binding	396	2.53e-01	-3.35e-02	0.721000
Synthesis of very long-chain fatty acyl-CoAs	24	2.58e-01	-1.34e-01	0.722000
Passive transport by Aquaporins	12	2.58e-01	-1.89e-01	0.722000
Chondroitin sulfate/dermatan sulfate metabolism	49	2.58e-01	9.34e-02	0.722000
Regulation of RUNX2 expression and activity	71	2.58e-01	7.76e-02	0.722000
Metabolic disorders of biological oxidation enzymes	32	2.59e-01	1.15e-01	0.722000
Signaling by high-kinase activity BRAF mutants	34	2.59e-01	-1.12e-01	0.722000
Acetylcholine binding and downstream events	13	2.61e-01	-1.80e-01	0.722000
Postsynaptic nicotinic acetylcholine receptors	13	2.61e-01	-1.80e-01	0.722000
Dectin-2 family	21	2.61e-01	1.42e-01	0.722000
Mitotic Spindle Checkpoint	107	2.62e-01	6.28e-02	0.722000
ERKs are inactivated	12	2.62e-01	-1.87e-01	0.722000
RUNX1 regulates transcription of genes involved in differentiation of HSCs	78	2.63e-01	7.33e-02	0.722000
Interleukin-3, Interleukin-5 and GM-CSF signaling	44	2.64e-01	-9.74e-02	0.722000
Condensation of Prometaphase Chromosomes	10	2.64e-01	-2.04e-01	0.722000
Cross-presentation of soluble exogenous antigens (endosomes)	49	2.65e-01	9.21e-02	0.722000
ERBB2 Activates PTK6 Signaling	13	2.65e-01	1.79e-01	0.722000
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	33	2.65e-01	1.12e-01	0.722000
Glycerophospholipid biosynthesis	124	2.66e-01	-5.79e-02	0.722000
Disorders of Developmental Biology	13	2.66e-01	-1.78e-01	0.722000
Disorders of Nervous System Development	13	2.66e-01	-1.78e-01	0.722000
Loss of function of MECP2 in Rett syndrome	13	2.66e-01	-1.78e-01	0.722000
Pervasive developmental disorders	13	2.66e-01	-1.78e-01	0.722000
Nuclear Envelope (NE) Reassembly	64	2.66e-01	8.04e-02	0.722000
YAP1- and WWTR1 (TAZ)-stimulated gene expression	14	2.67e-01	-1.72e-01	0.722000
SUMOylation of transcription cofactors	43	2.67e-01	-9.78e-02	0.722000
RAB geranylgeranylation	60	2.67e-01	8.28e-02	0.722000
G1/S-Specific Transcription	29	2.68e-01	1.19e-01	0.722000
PLC beta mediated events	50	2.68e-01	-9.07e-02	0.722000
Frs2-mediated activation	12	2.68e-01	-1.85e-01	0.722000
Regulation of HSF1-mediated heat shock response	76	2.69e-01	7.34e-02	0.722000
CD28 dependent Vav1 pathway	12	2.69e-01	-1.84e-01	0.722000
SHC-mediated cascade:FGFR1	21	2.69e-01	1.39e-01	0.722000
Transcriptional activation of mitochondrial biogenesis	52	2.70e-01	-8.84e-02	0.723000
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	50	2.71e-01	9.00e-02	0.723000
Intra-Golgi and retrograde Golgi-to-ER traffic	176	2.72e-01	4.81e-02	0.723000
InlB-mediated entry of Listeria monocytogenes into host cell	14	2.72e-01	-1.69e-01	0.723000
Biosynthesis of DHA-derived SPMs	15	2.73e-01	1.64e-01	0.723000
Ovarian tumor domain proteases	35	2.73e-01	-1.07e-01	0.723000
SUMOylation of ubiquitinylation proteins	38	2.74e-01	1.03e-01	0.723000
Orc1 removal from chromatin	69	2.74e-01	7.62e-02	0.723000
SARS-CoV-1 Infection	47	2.75e-01	-9.21e-02	0.725000
Removal of aminoterminal propeptides from gamma-carboxylated proteins	10	2.75e-01	-1.99e-01	0.725000
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	120	2.77e-01	-5.74e-02	0.729000
MASTL Facilitates Mitotic Progression	10	2.79e-01	-1.98e-01	0.730000
Activation of ATR in response to replication stress	36	2.80e-01	1.04e-01	0.730000
Metabolism of polyamines	58	2.80e-01	8.21e-02	0.730000
RUNX2 regulates bone development	30	2.80e-01	1.14e-01	0.730000
G-protein activation	27	2.80e-01	1.20e-01	0.730000
Olfactory Signaling Pathway	197	2.81e-01	-4.45e-02	0.731000
Transport of inorganic cations/anions and amino acids/oligopeptides	105	2.82e-01	6.08e-02	0.731000
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	10	2.83e-01	1.96e-01	0.733000
G2/M Checkpoints	134	2.84e-01	5.37e-02	0.734000
Trafficking of GluR2-containing AMPA receptors	17	2.85e-01	-1.50e-01	0.736000
Regulation of FZD by ubiquitination	19	2.86e-01	1.42e-01	0.736000
Signaling by the B Cell Receptor (BCR)	131	2.88e-01	5.38e-02	0.740000
RORA activates gene expression	18	2.88e-01	-1.45e-01	0.740000
Hyaluronan uptake and degradation	12	2.90e-01	1.76e-01	0.741000
Pre-NOTCH Transcription and Translation	48	2.92e-01	-8.79e-02	0.741000
Signaling by FGFR1 in disease	37	2.92e-01	1.00e-01	0.741000
Formation of HIV elongation complex in the absence of HIV Tat	46	2.93e-01	-8.97e-02	0.741000
Erythrocytes take up carbon dioxide and release oxygen	11	2.93e-01	-1.83e-01	0.741000
O2/CO2 exchange in erythrocytes	11	2.93e-01	-1.83e-01	0.741000
Spry regulation of FGF signaling	14	2.93e-01	-1.62e-01	0.741000
HS-GAG degradation	20	2.93e-01	-1.36e-01	0.741000
NIK-->noncanonical NF-kB signaling	57	2.93e-01	8.05e-02	0.741000
NEP/NS2 Interacts with the Cellular Export Machinery	31	2.94e-01	1.09e-01	0.742000
Switching of origins to a post-replicative state	88	2.95e-01	6.46e-02	0.742000
Presynaptic nicotinic acetylcholine receptors	11	2.95e-01	-1.82e-01	0.742000
Fatty acyl-CoA biosynthesis	35	2.98e-01	-1.02e-01	0.747000
Defective GALNT12 causes colorectal cancer 1 (CRCS1)	12	2.98e-01	1.73e-01	0.747000
HSF1-dependent transactivation	30	3.00e-01	-1.09e-01	0.750000
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	35	3.01e-01	-1.01e-01	0.751000
SHC-mediated cascade:FGFR4	19	3.02e-01	1.37e-01	0.751000
Dopamine Neurotransmitter Release Cycle	23	3.02e-01	1.24e-01	0.751000
p75NTR recruits signalling complexes	12	3.03e-01	-1.72e-01	0.752000
Homologous DNA Pairing and Strand Exchange	41	3.03e-01	9.29e-02	0.752000
Transcriptional regulation by RUNX1	188	3.04e-01	-4.35e-02	0.753000
Regulation of MECP2 expression and activity	30	3.05e-01	-1.08e-01	0.754000
Defective B3GALTL causes Peters-plus syndrome (PpS)	36	3.08e-01	9.83e-02	0.758000
Biosynthesis of specialized proresolving mediators (SPMs)	17	3.08e-01	1.43e-01	0.758000
Phosphorylation of CD3 and TCR zeta chains	18	3.09e-01	-1.39e-01	0.758000
Depolymerisation of the Nuclear Lamina	15	3.09e-01	1.52e-01	0.758000
RAS processing	19	3.10e-01	1.34e-01	0.759000
Gap-filling DNA repair synthesis and ligation in TC-NER	60	3.10e-01	-7.57e-02	0.759000
Translesion synthesis by POLK	16	3.13e-01	-1.46e-01	0.763000
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	11	3.13e-01	1.76e-01	0.763000
CDC6 association with the ORC:origin complex	11	3.14e-01	1.75e-01	0.765000
Interleukin-6 signaling	11	3.16e-01	-1.75e-01	0.767000
FCERI mediated NF-kB activation	100	3.17e-01	5.80e-02	0.767000
EPHA-mediated growth cone collapse	15	3.17e-01	-1.49e-01	0.767000
Downstream signal transduction	29	3.18e-01	-1.07e-01	0.767000
Neurotransmitter receptors and postsynaptic signal transmission	176	3.18e-01	-4.37e-02	0.767000
Signaling by FGFR1	47	3.19e-01	8.41e-02	0.768000
tRNA modification in the nucleus and cytosol	42	3.21e-01	8.85e-02	0.771000
Interaction between L1 and Ankyrins	29	3.22e-01	-1.06e-01	0.771000
Post-translational protein phosphorylation	104	3.22e-01	-5.63e-02	0.771000
Gap junction assembly	17	3.23e-01	-1.39e-01	0.772000
Interleukin-37 signaling	20	3.24e-01	1.27e-01	0.774000
TNFR1-induced NFkappaB signaling pathway	26	3.26e-01	-1.11e-01	0.777000
Amino acids regulate mTORC1	50	3.27e-01	8.02e-02	0.777000
TICAM1-dependent activation of IRF3/IRF7	10	3.27e-01	1.79e-01	0.777000
Synthesis of IP3 and IP4 in the cytosol	26	3.29e-01	-1.11e-01	0.777000
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	31	3.29e-01	1.01e-01	0.777000
Regulation of Glucokinase by Glucokinase Regulatory Protein	31	3.29e-01	1.01e-01	0.777000
Degradation of the extracellular matrix	104	3.29e-01	5.54e-02	0.777000
S Phase	158	3.30e-01	4.49e-02	0.777000
SHC1 events in EGFR signaling	14	3.30e-01	1.50e-01	0.777000
Unfolded Protein Response (UPR)	91	3.30e-01	5.91e-02	0.777000
SUMOylation of intracellular receptors	30	3.31e-01	-1.03e-01	0.777000
Diseases associated with N-glycosylation of proteins	16	3.33e-01	1.40e-01	0.778000
Nervous system development	514	3.34e-01	-2.50e-02	0.778000
Signaling by FGFR	79	3.34e-01	6.29e-02	0.778000
Anti-inflammatory response favouring Leishmania parasite infection	174	3.34e-01	-4.25e-02	0.778000
Leishmania parasite growth and survival	174	3.34e-01	-4.25e-02	0.778000
Presynaptic phase of homologous DNA pairing and strand exchange	38	3.35e-01	9.05e-02	0.778000
Glucose metabolism	87	3.35e-01	-5.98e-02	0.778000
Amine ligand-binding receptors	36	3.36e-01	9.26e-02	0.779000
Chromosome Maintenance	98	3.39e-01	5.59e-02	0.784000
Fanconi Anemia Pathway	35	3.40e-01	-9.32e-02	0.784000
Signaling by PDGFR in disease	19	3.40e-01	-1.26e-01	0.784000
FGFR1 ligand binding and activation	15	3.43e-01	1.41e-01	0.790000
Transport of bile salts and organic acids, metal ions and amine compounds	80	3.46e-01	6.10e-02	0.794000
Inflammasomes	20	3.49e-01	1.21e-01	0.798000
RAF activation	32	3.49e-01	-9.57e-02	0.798000
Constitutive Signaling by Aberrant PI3K in Cancer	74	3.50e-01	6.28e-02	0.798000
Non-integrin membrane-ECM interactions	41	3.52e-01	8.41e-02	0.798000
Regulation of commissural axon pathfinding by SLIT and ROBO	10	3.52e-01	1.70e-01	0.798000
Cellular hexose transport	19	3.52e-01	-1.23e-01	0.798000
Role of LAT2/NTAL/LAB on calcium mobilization	40	3.52e-01	8.50e-02	0.798000
CS/DS degradation	14	3.53e-01	1.43e-01	0.798000
ADORA2B mediated anti-inflammatory cytokines production	114	3.53e-01	-5.04e-02	0.798000
Classical antibody-mediated complement activation	32	3.53e-01	9.49e-02	0.798000
FRS-mediated FGFR1 signaling	23	3.53e-01	1.12e-01	0.798000
Nuclear Envelope Breakdown	50	3.54e-01	7.57e-02	0.799000
DSCAM interactions	11	3.57e-01	1.61e-01	0.799000
Synthesis of PIPs at the plasma membrane	51	3.57e-01	-7.46e-02	0.799000
Opioid Signalling	86	3.57e-01	-5.75e-02	0.799000
Metabolism of non-coding RNA	51	3.58e-01	7.44e-02	0.799000
snRNP Assembly	51	3.58e-01	7.44e-02	0.799000
ADP signalling through P2Y purinoceptor 1	23	3.58e-01	1.11e-01	0.799000
Cytokine Signaling in Immune system	801	3.59e-01	-1.91e-02	0.799000
Pyrimidine salvage	10	3.60e-01	-1.67e-01	0.799000
Activation of NF-kappaB in B cells	63	3.60e-01	6.67e-02	0.799000
RHO GTPases Activate Formins	118	3.61e-01	4.88e-02	0.799000
Signaling by BMP	26	3.61e-01	1.04e-01	0.799000
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	12	3.61e-01	-1.52e-01	0.799000
Free fatty acids regulate insulin secretion	10	3.63e-01	-1.66e-01	0.799000
Acyl chain remodelling of PI	16	3.63e-01	1.31e-01	0.799000
Autodegradation of the E3 ubiquitin ligase COP1	48	3.64e-01	7.57e-02	0.799000
The NLRP3 inflammasome	15	3.64e-01	1.35e-01	0.799000
Cholesterol biosynthesis	22	3.65e-01	1.12e-01	0.799000
ATF6 (ATF6-alpha) activates chaperones	12	3.65e-01	-1.51e-01	0.799000
Platelet activation, signaling and aggregation	252	3.65e-01	-3.32e-02	0.799000
Vpu mediated degradation of CD4	50	3.66e-01	7.40e-02	0.799000
Regulation of Apoptosis	51	3.66e-01	7.32e-02	0.799000
Cell Cycle	608	3.66e-01	2.15e-02	0.799000
Heparan sulfate/heparin (HS-GAG) metabolism	51	3.67e-01	-7.30e-02	0.799000
SARS-CoV Infections	138	3.68e-01	-4.45e-02	0.799000
Endogenous sterols	24	3.70e-01	1.06e-01	0.802000
HDACs deacetylate histones	39	3.70e-01	-8.30e-02	0.802000
Laminin interactions	23	3.72e-01	-1.08e-01	0.805000
Nuclear Receptor transcription pathway	53	3.73e-01	-7.08e-02	0.805000
CDK-mediated phosphorylation and removal of Cdc6	70	3.74e-01	6.15e-02	0.805000
Caspase-mediated cleavage of cytoskeletal proteins	12	3.74e-01	1.48e-01	0.805000
Signaling by FGFR3 fusions in cancer	10	3.74e-01	1.62e-01	0.805000
IRE1alpha activates chaperones	50	3.75e-01	7.25e-02	0.807000
Neurexins and neuroligins	54	3.76e-01	6.96e-02	0.808000
PINK1-PRKN Mediated Mitophagy	19	3.79e-01	-1.17e-01	0.811000
SLC-mediated transmembrane transport	240	3.86e-01	3.25e-02	0.824000
Export of Viral Ribonucleoproteins from Nucleus	32	3.87e-01	8.84e-02	0.824000
FGFR4 ligand binding and activation	13	3.88e-01	1.38e-01	0.824000
Tryptophan catabolism	14	3.88e-01	-1.33e-01	0.824000
TCF dependent signaling in response to WNT	177	3.89e-01	-3.76e-02	0.824000
Negative regulators of DDX58/IFIH1 signaling	31	3.89e-01	-8.94e-02	0.824000
Pentose phosphate pathway	14	3.90e-01	1.33e-01	0.824000
Signaling by Retinoic Acid	39	3.90e-01	7.96e-02	0.824000
Signaling by NTRK1 (TRKA)	113	3.91e-01	-4.68e-02	0.824000
Cyclin A:Cdk2-associated events at S phase entry	83	3.91e-01	5.45e-02	0.824000
HDR through Homologous Recombination (HRR)	63	3.91e-01	6.25e-02	0.824000
Acyl chain remodelling of PG	17	3.92e-01	1.20e-01	0.824000
Processing of DNA double-strand break ends	66	3.92e-01	6.09e-02	0.824000
Clathrin-mediated endocytosis	139	3.94e-01	-4.19e-02	0.827000
PI Metabolism	80	3.95e-01	5.51e-02	0.827000
FRS-mediated FGFR4 signaling	21	3.96e-01	1.07e-01	0.828000
Interconversion of nucleotide di- and triphosphates	28	3.98e-01	9.24e-02	0.831000
Regulation of TNFR1 signaling	34	3.99e-01	-8.36e-02	0.831000
Binding and Uptake of Ligands by Scavenger Receptors	63	3.99e-01	6.14e-02	0.831000
Ion transport by P-type ATPases	52	4.00e-01	-6.75e-02	0.831000
Cellular responses to stress	475	4.00e-01	2.26e-02	0.831000
Ca-dependent events	34	4.01e-01	-8.33e-02	0.831000
XBP1(S) activates chaperone genes	48	4.03e-01	6.98e-02	0.834000
Meiotic recombination	37	4.03e-01	7.95e-02	0.834000
IKK complex recruitment mediated by RIP1	18	4.04e-01	1.14e-01	0.834000
Ub-specific processing proteases	160	4.06e-01	-3.81e-02	0.837000
Transport of Ribonucleoproteins into the Host Nucleus	31	4.08e-01	8.58e-02	0.837000
SUMOylation of DNA damage response and repair proteins	73	4.09e-01	5.59e-02	0.837000
SCF-beta-TrCP mediated degradation of Emi1	53	4.10e-01	6.55e-02	0.837000
Autophagy	122	4.11e-01	-4.31e-02	0.837000
Gap-filling DNA repair synthesis and ligation in GG-NER	23	4.11e-01	-9.90e-02	0.837000
Ephrin signaling	19	4.11e-01	-1.09e-01	0.837000
Signaling by ERBB2 TMD/JMD mutants	20	4.12e-01	1.06e-01	0.837000
The canonical retinoid cycle in rods (twilight vision)	23	4.12e-01	9.88e-02	0.837000
The phototransduction cascade	31	4.13e-01	8.50e-02	0.837000
Downstream signaling events of B Cell Receptor (BCR)	76	4.13e-01	5.43e-02	0.837000
Intrinsic Pathway for Apoptosis	46	4.14e-01	-6.96e-02	0.837000
Signaling by VEGF	100	4.15e-01	-4.72e-02	0.837000
WNT ligand biogenesis and trafficking	25	4.15e-01	-9.42e-02	0.837000
Regulation of PTEN gene transcription	58	4.16e-01	-6.18e-02	0.837000
Constitutive Signaling by AKT1 E17K in Cancer	25	4.16e-01	-9.41e-02	0.837000
FCGR3A-mediated IL10 synthesis	64	4.16e-01	-5.88e-02	0.837000
CD28 dependent PI3K/Akt signaling	22	4.16e-01	1.00e-01	0.837000
Translesion synthesis by POLI	16	4.16e-01	-1.17e-01	0.837000
Energy dependent regulation of mTOR by LKB1-AMPK	28	4.17e-01	8.86e-02	0.838000
SUMOylation of SUMOylation proteins	34	4.19e-01	8.00e-02	0.841000
Apoptotic cleavage of cell adhesion proteins	11	4.21e-01	-1.40e-01	0.841000
Constitutive Signaling by NOTCH1 HD Domain Mutants	14	4.21e-01	-1.24e-01	0.841000
Signaling by NOTCH1 HD Domain Mutants in Cancer	14	4.21e-01	-1.24e-01	0.841000
Suppression of phagosomal maturation	12	4.22e-01	-1.34e-01	0.841000
PCNA-Dependent Long Patch Base Excision Repair	20	4.23e-01	-1.03e-01	0.841000
Cargo recognition for clathrin-mediated endocytosis	102	4.24e-01	-4.59e-02	0.841000
DNA methylation	15	4.24e-01	-1.19e-01	0.841000
Uptake and function of anthrax toxins	10	4.25e-01	-1.46e-01	0.841000
Autodegradation of Cdh1 by Cdh1:APC/C	61	4.25e-01	5.91e-02	0.841000
DNA Replication	123	4.26e-01	4.16e-02	0.841000
Glutamate and glutamine metabolism	13	4.26e-01	1.27e-01	0.841000
Vpr-mediated nuclear import of PICs	32	4.26e-01	8.12e-02	0.841000
Negative regulation of MET activity	20	4.27e-01	-1.03e-01	0.841000
Recycling pathway of L1	27	4.27e-01	-8.83e-02	0.841000
NF-kB is activated and signals survival	11	4.29e-01	-1.38e-01	0.843000
Antigen processing-Cross presentation	93	4.30e-01	4.74e-02	0.843000
Downregulation of ERBB2 signaling	26	4.32e-01	8.90e-02	0.847000
Dectin-1 mediated noncanonical NF-kB signaling	60	4.35e-01	5.83e-02	0.847000
Insulin processing	27	4.35e-01	-8.68e-02	0.847000
Nucleobase biosynthesis	13	4.35e-01	1.25e-01	0.847000
Metalloprotease DUBs	18	4.36e-01	1.06e-01	0.847000
MET activates PTK2 signaling	18	4.37e-01	-1.06e-01	0.847000
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	49	4.37e-01	6.41e-02	0.847000
p53-Independent DNA Damage Response	49	4.37e-01	6.41e-02	0.847000
p53-Independent G1/S DNA damage checkpoint	49	4.37e-01	6.41e-02	0.847000
Cell surface interactions at the vascular wall	153	4.39e-01	-3.63e-02	0.847000
Defective CFTR causes cystic fibrosis	59	4.40e-01	5.82e-02	0.847000
Metabolism of amino acids and derivatives	337	4.41e-01	-2.45e-02	0.847000
NGF-stimulated transcription	39	4.41e-01	-7.13e-02	0.847000
HSF1 activation	24	4.42e-01	-9.07e-02	0.847000
Cellular responses to external stimuli	481	4.42e-01	2.05e-02	0.847000
RUNX3 regulates NOTCH signaling	12	4.42e-01	-1.28e-01	0.847000
Cyclin A/B1/B2 associated events during G2/M transition	23	4.42e-01	9.26e-02	0.847000
FOXO-mediated transcription of cell cycle genes	16	4.44e-01	-1.11e-01	0.847000
Deubiquitination	232	4.45e-01	-2.91e-02	0.847000
MET receptor recycling	10	4.46e-01	1.39e-01	0.847000
CLEC7A (Dectin-1) signaling	95	4.46e-01	4.52e-02	0.847000
RNA Polymerase I Promoter Escape	38	4.47e-01	7.14e-02	0.847000
Nicotinate metabolism	31	4.47e-01	7.89e-02	0.847000
RNA Polymerase III Transcription Initiation From Type 1 Promoter	24	4.48e-01	-8.95e-02	0.847000
Deadenylation-dependent mRNA decay	51	4.48e-01	-6.14e-02	0.847000
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	11	4.48e-01	-1.32e-01	0.847000
Prolonged ERK activation events	14	4.49e-01	-1.17e-01	0.847000
Cargo concentration in the ER	29	4.49e-01	-8.12e-02	0.847000
Pyrimidine catabolism	12	4.50e-01	-1.26e-01	0.847000
RNA Polymerase I Transcription Termination	28	4.50e-01	8.25e-02	0.847000
Regulation of ornithine decarboxylase (ODC)	50	4.51e-01	6.17e-02	0.847000
SUMOylation of DNA replication proteins	44	4.51e-01	6.57e-02	0.847000
Platelet Adhesion to exposed collagen	13	4.51e-01	-1.21e-01	0.847000
MAPK targets/ Nuclear events mediated by MAP kinases	30	4.53e-01	-7.92e-02	0.847000
Heme biosynthesis	13	4.53e-01	1.20e-01	0.847000
Axon guidance	491	4.53e-01	-1.98e-02	0.847000
C-type lectin receptors (CLRs)	128	4.54e-01	3.84e-02	0.847000
Scavenging by Class A Receptors	17	4.54e-01	1.05e-01	0.847000
Potassium Channels	98	4.55e-01	-4.37e-02	0.847000
Regulation of TP53 Activity through Association with Co-factors	13	4.57e-01	-1.19e-01	0.848000
Transcriptional Regulation by VENTX	36	4.58e-01	-7.15e-02	0.848000
Regulation of activated PAK-2p34 by proteasome mediated degradation	48	4.58e-01	6.20e-02	0.848000
Cyclin E associated events during G1/S transition	81	4.58e-01	4.77e-02	0.848000
Stabilization of p53	52	4.58e-01	5.95e-02	0.848000
Regulation of PTEN stability and activity	67	4.59e-01	5.24e-02	0.848000
GAB1 signalosome	17	4.59e-01	1.04e-01	0.848000
Creatine metabolism	10	4.60e-01	-1.35e-01	0.849000
Rap1 signalling	14	4.61e-01	-1.14e-01	0.849000
Synthesis of bile acids and bile salts via 27-hydroxycholesterol	11	4.61e-01	1.28e-01	0.849000
Cellular Senescence	136	4.62e-01	-3.65e-02	0.849000
STING mediated induction of host immune responses	16	4.63e-01	-1.06e-01	0.849000
TRAF3-dependent IRF activation pathway	12	4.65e-01	-1.22e-01	0.851000
Elevation of cytosolic Ca2+ levels	16	4.66e-01	1.05e-01	0.851000
Signaling by Hedgehog	132	4.66e-01	3.67e-02	0.851000
G beta:gamma signalling through PLC beta	19	4.66e-01	9.65e-02	0.851000
Synthesis of PA	37	4.67e-01	6.91e-02	0.851000
Gene expression (Transcription)	1222	4.68e-01	-1.24e-02	0.851000
Regulation of RUNX1 Expression and Activity	23	4.68e-01	-8.75e-02	0.851000
GABA synthesis, release, reuptake and degradation	19	4.68e-01	-9.61e-02	0.851000
mRNA Capping	27	4.71e-01	8.02e-02	0.854000
Pregnenolone biosynthesis	11	4.71e-01	1.26e-01	0.854000
HCMV Infection	89	4.74e-01	-4.39e-02	0.858000
TCR signaling	108	4.75e-01	-3.98e-02	0.859000
MAP kinase activation	60	4.77e-01	-5.31e-02	0.860000
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon	13	4.77e-01	1.14e-01	0.860000
Class B/2 (Secretin family receptors)	85	4.77e-01	4.46e-02	0.860000
Activation of BAD and translocation to mitochondria	15	4.80e-01	-1.05e-01	0.861000
Regulation of pyruvate dehydrogenase (PDH) complex	16	4.80e-01	-1.02e-01	0.861000
Interleukin-20 family signaling	23	4.81e-01	-8.50e-02	0.861000
Josephin domain DUBs	10	4.81e-01	1.29e-01	0.861000
HDR through Single Strand Annealing (SSA)	37	4.82e-01	6.68e-02	0.861000
ADP signalling through P2Y purinoceptor 12	21	4.82e-01	8.85e-02	0.861000
Negative regulation of FGFR3 signaling	27	4.83e-01	7.79e-02	0.861000
Signaling by FGFR2	67	4.84e-01	4.95e-02	0.861000
TRP channels	25	4.85e-01	8.08e-02	0.861000
Resolution of Abasic Sites (AP sites)	37	4.87e-01	6.61e-02	0.861000
Interleukin receptor SHC signaling	27	4.87e-01	-7.73e-02	0.861000
Regulation of actin dynamics for phagocytic cup formation	85	4.87e-01	-4.36e-02	0.861000
MyD88 cascade initiated on plasma membrane	76	4.87e-01	-4.61e-02	0.861000
Toll Like Receptor 10 (TLR10) Cascade	76	4.87e-01	-4.61e-02	0.861000
Toll Like Receptor 5 (TLR5) Cascade	76	4.87e-01	-4.61e-02	0.861000
Signal amplification	31	4.90e-01	7.16e-02	0.864000
Platelet sensitization by LDL	16	4.91e-01	9.95e-02	0.864000
Defective B3GALT6 causes EDSP2 and SEMDJL1	19	4.91e-01	9.13e-02	0.864000
Inactivation, recovery and regulation of the phototransduction cascade	30	4.91e-01	7.27e-02	0.864000
G alpha (z) signalling events	47	4.94e-01	-5.76e-02	0.868000
COPI-dependent Golgi-to-ER retrograde traffic	78	4.95e-01	-4.48e-02	0.868000
Hh mutants that don't undergo autocatalytic processing are degraded by ERAD	54	4.97e-01	5.35e-02	0.869000
Mitotic Prometaphase	182	4.98e-01	2.92e-02	0.869000
Signaling by ROBO receptors	190	4.98e-01	2.86e-02	0.869000
Transcription of E2F targets under negative control by DREAM complex	19	4.98e-01	8.98e-02	0.869000
Degradation of DVL	55	4.98e-01	5.28e-02	0.869000
Arachidonic acid metabolism	53	5.02e-01	5.34e-02	0.874000
RNA Polymerase III Transcription Initiation From Type 2 Promoter	23	5.02e-01	-8.08e-02	0.874000
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	56	5.03e-01	5.17e-02	0.874000
Phospholipase C-mediated cascade: FGFR1	16	5.04e-01	9.66e-02	0.874000
DNA Double-Strand Break Repair	131	5.04e-01	3.38e-02	0.874000
Glucagon-type ligand receptors	30	5.05e-01	7.03e-02	0.875000
Trafficking and processing of endosomal TLR	12	5.06e-01	1.11e-01	0.876000
Activation of kainate receptors upon glutamate binding	29	5.08e-01	7.11e-02	0.876000
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	14	5.08e-01	1.02e-01	0.876000
Signaling by ERBB4	55	5.08e-01	-5.16e-02	0.876000
SCF(Skp2)-mediated degradation of p27/p21	58	5.09e-01	5.02e-02	0.876000
Signaling by ERBB2 ECD mutants	14	5.13e-01	1.01e-01	0.879000
Regulation of RAS by GAPs	66	5.13e-01	4.66e-02	0.879000
Toll Like Receptor 7/8 (TLR7/8) Cascade	81	5.13e-01	-4.21e-02	0.879000
Interferon gamma signaling	77	5.14e-01	-4.30e-02	0.879000
Response of EIF2AK1 (HRI) to heme deficiency	15	5.14e-01	9.72e-02	0.879000
Gastrin-CREB signalling pathway via PKC and MAPK	17	5.15e-01	9.13e-02	0.879000
Purine catabolism	18	5.15e-01	8.87e-02	0.879000
Interleukin-15 signaling	14	5.17e-01	-1.00e-01	0.880000
Scavenging of heme from plasma	38	5.17e-01	6.07e-02	0.880000
Centrosome maturation	79	5.18e-01	-4.21e-02	0.880000
Recruitment of mitotic centrosome proteins and complexes	79	5.18e-01	-4.21e-02	0.880000
CREB1 phosphorylation through the activation of Adenylate Cyclase	11	5.20e-01	-1.12e-01	0.883000
Adaptive Immune System	688	5.21e-01	-1.44e-02	0.883000
Host Interactions of HIV factors	124	5.22e-01	3.33e-02	0.883000
Heme degradation	13	5.23e-01	-1.02e-01	0.883000
Sema3A PAK dependent Axon repulsion	15	5.23e-01	-9.53e-02	0.883000
Phase 2 - plateau phase	14	5.26e-01	9.79e-02	0.888000
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	19	5.27e-01	8.38e-02	0.889000
Formation of tubulin folding intermediates by CCT/TriC	21	5.28e-01	-7.95e-02	0.889000
RNA Polymerase III Chain Elongation	14	5.29e-01	-9.72e-02	0.889000
Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)	12	5.30e-01	1.05e-01	0.890000
APC/C:Cdc20 mediated degradation of Cyclin B	22	5.30e-01	-7.73e-02	0.890000
G beta:gamma signalling through PI3Kgamma	24	5.32e-01	7.37e-02	0.892000
Synthesis of PE	13	5.34e-01	9.97e-02	0.892000
Synthesis of DNA	116	5.34e-01	3.35e-02	0.892000
Triglyceride catabolism	23	5.36e-01	-7.46e-02	0.892000
Leishmania infection	254	5.36e-01	-2.26e-02	0.892000
G alpha (q) signalling events	199	5.36e-01	-2.55e-02	0.892000
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation	12	5.37e-01	-1.03e-01	0.892000
Regulation of innate immune responses to cytosolic DNA	13	5.37e-01	9.90e-02	0.892000
Purine ribonucleoside monophosphate biosynthesis	10	5.38e-01	1.13e-01	0.892000
Cargo trafficking to the periciliary membrane	49	5.38e-01	5.09e-02	0.892000
VEGFR2 mediated vascular permeability	26	5.39e-01	-6.96e-02	0.893000
Removal of the Flap Intermediate	13	5.43e-01	9.75e-02	0.898000
Fertilization	20	5.44e-01	-7.83e-02	0.898000
Regulation of PLK1 Activity at G2/M Transition	83	5.45e-01	-3.85e-02	0.898000
Base Excision Repair	54	5.45e-01	4.76e-02	0.898000
CLEC7A (Dectin-1) induces NFAT activation	11	5.45e-01	-1.05e-01	0.898000
RNA polymerase II transcribes snRNA genes	68	5.46e-01	-4.23e-02	0.899000
Gene Silencing by RNA	85	5.47e-01	3.78e-02	0.899000
Interleukin-2 family signaling	42	5.47e-01	-5.37e-02	0.899000
GRB2 events in EGFR signaling	13	5.48e-01	9.62e-02	0.899000
Synthesis of bile acids and bile salts via 24-hydroxycholesterol	10	5.49e-01	1.09e-01	0.899000
DNA Repair	281	5.49e-01	-2.08e-02	0.899000
Processive synthesis on the lagging strand	14	5.53e-01	9.15e-02	0.902000
RNA Polymerase II Transcription	1089	5.54e-01	-1.07e-02	0.902000
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	49	5.54e-01	4.88e-02	0.902000
Telomere C-strand synthesis initiation	13	5.54e-01	9.47e-02	0.902000
Mitotic Prophase	89	5.55e-01	3.62e-02	0.902000
Response to elevated platelet cytosolic Ca2+	128	5.55e-01	-3.02e-02	0.902000
Cellular response to hypoxia	73	5.56e-01	-3.99e-02	0.902000
Translocation of SLC2A4 (GLUT4) to the plasma membrane	50	5.57e-01	-4.81e-02	0.902000
Phosphorylation of the APC/C	19	5.57e-01	-7.78e-02	0.902000
Intracellular signaling by second messengers	306	5.59e-01	-1.95e-02	0.903000
EPH-Ephrin signaling	90	5.60e-01	-3.56e-02	0.903000
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins	11	5.61e-01	-1.01e-01	0.903000
rRNA modification in the nucleus and cytosol	57	5.62e-01	4.45e-02	0.903000
Metabolism of porphyrins	24	5.62e-01	-6.84e-02	0.903000
HS-GAG biosynthesis	28	5.62e-01	-6.33e-02	0.903000
Purine salvage	13	5.63e-01	9.28e-02	0.903000
CD22 mediated BCR regulation	31	5.63e-01	6.01e-02	0.903000
Hh mutants abrogate ligand secretion	57	5.63e-01	4.43e-02	0.903000
Transcriptional regulation of granulopoiesis	40	5.64e-01	-5.27e-02	0.904000
Abortive elongation of HIV-1 transcript in the absence of Tat	21	5.65e-01	-7.25e-02	0.904000
Metabolism of nitric oxide: NOS3 activation and regulation	14	5.67e-01	-8.85e-02	0.904000
Nuclear Pore Complex (NPC) Disassembly	34	5.67e-01	5.68e-02	0.904000
Antigen processing: Ubiquitination & Proteasome degradation	290	5.67e-01	-1.96e-02	0.904000
Tie2 Signaling	18	5.68e-01	7.78e-02	0.904000
Beta-catenin phosphorylation cascade	16	5.71e-01	8.19e-02	0.907000
Ubiquitin-dependent degradation of Cyclin D	50	5.71e-01	4.63e-02	0.907000
Phospholipase C-mediated cascade; FGFR4	14	5.72e-01	8.73e-02	0.907000
EGFR downregulation	30	5.73e-01	-5.94e-02	0.907000
Glycosphingolipid metabolism	41	5.73e-01	5.09e-02	0.907000
Hedgehog ligand biogenesis	62	5.73e-01	4.14e-02	0.907000
Golgi-to-ER retrograde transport	111	5.74e-01	-3.09e-02	0.907000
MyD88 dependent cascade initiated on endosome	80	5.76e-01	-3.62e-02	0.908000
Apoptotic factor-mediated response	14	5.76e-01	8.63e-02	0.908000
Signaling by EGFR	49	5.76e-01	-4.62e-02	0.908000
Disassembly of the destruction complex and recruitment of AXIN to the membrane	30	5.77e-01	5.89e-02	0.908000
Fcgamma receptor (FCGR) dependent phagocytosis	110	5.77e-01	-3.08e-02	0.908000
Rab regulation of trafficking	117	5.79e-01	2.97e-02	0.908000
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	17	5.79e-01	-7.78e-02	0.908000
Response of Mtb to phagocytosis	22	5.79e-01	-6.83e-02	0.908000
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	17	5.80e-01	7.74e-02	0.908000
Transcription of the HIV genome	68	5.81e-01	3.87e-02	0.908000
Lysine catabolism	12	5.81e-01	-9.20e-02	0.908000
TNFs bind their physiological receptors	27	5.82e-01	-6.12e-02	0.908000
CD209 (DC-SIGN) signaling	19	5.84e-01	-7.26e-02	0.908000
Membrane Trafficking	579	5.84e-01	-1.34e-02	0.908000
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	98	5.84e-01	3.20e-02	0.908000
Fatty acid metabolism	164	5.86e-01	-2.47e-02	0.908000
Cyclin D associated events in G1	43	5.86e-01	-4.80e-02	0.908000
G1 Phase	43	5.86e-01	-4.80e-02	0.908000
DAP12 signaling	29	5.86e-01	5.84e-02	0.908000
Negative regulation of TCF-dependent signaling by WNT ligand antagonists	15	5.88e-01	-8.09e-02	0.908000
Interleukin-27 signaling	11	5.89e-01	-9.41e-02	0.908000
VEGFR2 mediated cell proliferation	19	5.90e-01	7.15e-02	0.908000
Mitotic G1 phase and G1/S transition	143	5.92e-01	2.60e-02	0.908000
Thromboxane signalling through TP receptor	22	5.93e-01	6.59e-02	0.908000
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	11	5.94e-01	9.29e-02	0.908000
Nicotinamide salvaging	19	5.94e-01	7.07e-02	0.908000
EPH-ephrin mediated repulsion of cells	48	5.94e-01	4.44e-02	0.908000
RHO GTPases activate IQGAPs	11	5.95e-01	-9.26e-02	0.908000
NoRC negatively regulates rRNA expression	54	5.95e-01	4.18e-02	0.908000
tRNA processing	118	5.95e-01	2.83e-02	0.908000
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	17	5.96e-01	7.44e-02	0.908000
Meiotic synapsis	41	5.96e-01	-4.79e-02	0.908000
Glycogen storage diseases	14	5.97e-01	-8.17e-02	0.908000
Toll-like Receptor Cascades	138	5.98e-01	-2.60e-02	0.908000
Metabolism of carbohydrates	275	5.98e-01	1.85e-02	0.908000
Presynaptic function of Kainate receptors	20	6.00e-01	6.78e-02	0.908000
Interleukin-17 signaling	68	6.00e-01	-3.68e-02	0.908000
Caspase activation via Death Receptors in the presence of ligand	11	6.01e-01	9.11e-02	0.908000
Regulation of APC/C activators between G1/S and early anaphase	78	6.01e-01	3.43e-02	0.908000
Activation of GABAB receptors	42	6.01e-01	-4.66e-02	0.908000
GABA B receptor activation	42	6.01e-01	-4.66e-02	0.908000
Transcriptional regulation by small RNAs	54	6.01e-01	4.11e-02	0.908000
Long-term potentiation	22	6.02e-01	-6.42e-02	0.908000
Sphingolipid metabolism	84	6.02e-01	-3.29e-02	0.908000
HDMs demethylate histones	21	6.06e-01	-6.50e-02	0.913000
Signaling by cytosolic FGFR1 fusion mutants	17	6.06e-01	7.22e-02	0.913000
Mitotic Telophase/Cytokinesis	13	6.10e-01	-8.17e-02	0.913000
Degradation of GLI2 by the proteasome	56	6.12e-01	3.92e-02	0.913000
ATF4 activates genes in response to endoplasmic reticulum stress	26	6.12e-01	5.74e-02	0.913000
VLDLR internalisation and degradation	12	6.13e-01	-8.44e-02	0.913000
Senescence-Associated Secretory Phenotype (SASP)	56	6.13e-01	-3.90e-02	0.913000
Triglyceride metabolism	36	6.14e-01	-4.86e-02	0.913000
HSP90 chaperone cycle for steroid hormone receptors (SHR)	35	6.14e-01	-4.92e-02	0.913000
NOTCH4 Intracellular Domain Regulates Transcription	18	6.15e-01	-6.86e-02	0.913000
Cytochrome c-mediated apoptotic response	11	6.17e-01	-8.72e-02	0.913000
Viral Messenger RNA Synthesis	41	6.17e-01	4.52e-02	0.913000
p53-Dependent G1 DNA Damage Response	61	6.18e-01	3.70e-02	0.913000
p53-Dependent G1/S DNA damage checkpoint	61	6.18e-01	3.70e-02	0.913000
Signaling by WNT	271	6.18e-01	-1.76e-02	0.913000
Signaling by PDGF	50	6.19e-01	-4.07e-02	0.913000
IRAK4 deficiency (TLR2/4)	10	6.20e-01	9.07e-02	0.913000
Regulation of RUNX3 expression and activity	52	6.20e-01	3.98e-02	0.913000
Serotonin Neurotransmitter Release Cycle	18	6.20e-01	6.75e-02	0.913000
MAP2K and MAPK activation	38	6.21e-01	-4.64e-02	0.913000
Caspase activation via extrinsic apoptotic signalling pathway	21	6.22e-01	6.21e-02	0.913000
mTORC1-mediated signalling	22	6.22e-01	-6.06e-02	0.913000
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	40	6.23e-01	-4.49e-02	0.913000
Platelet degranulation	123	6.25e-01	-2.55e-02	0.913000
Signaling by NOTCH4	78	6.26e-01	-3.19e-02	0.913000
Recruitment of NuMA to mitotic centrosomes	78	6.27e-01	-3.19e-02	0.913000
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	53	6.27e-01	3.86e-02	0.913000
Metabolism of steroid hormones	27	6.28e-01	-5.39e-02	0.913000
Downstream TCR signaling	88	6.28e-01	-2.99e-02	0.913000
Activation of G protein gated Potassium channels	28	6.28e-01	5.29e-02	0.913000
G protein gated Potassium channels	28	6.28e-01	5.29e-02	0.913000
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	28	6.28e-01	5.29e-02	0.913000
G1/S DNA Damage Checkpoints	62	6.28e-01	3.55e-02	0.913000
Negative epigenetic regulation of rRNA expression	57	6.30e-01	3.69e-02	0.913000
Regulation of TP53 Activity through Methylation	16	6.31e-01	6.94e-02	0.913000
Golgi Associated Vesicle Biogenesis	54	6.32e-01	-3.77e-02	0.913000
Cleavage of the damaged purine	20	6.32e-01	6.19e-02	0.913000
Depurination	20	6.32e-01	6.19e-02	0.913000
Recognition and association of DNA glycosylase with site containing an affected purine	20	6.32e-01	6.19e-02	0.913000
Mitochondrial tRNA aminoacylation	20	6.32e-01	6.18e-02	0.913000
Transport of Mature Transcript to Cytoplasm	80	6.33e-01	3.09e-02	0.913000
Defective EXT1 causes exostoses 1, TRPS2 and CHDS	13	6.33e-01	-7.64e-02	0.913000
Defective EXT2 causes exostoses 2	13	6.33e-01	-7.64e-02	0.913000
Signaling by EGFR in Cancer	23	6.33e-01	5.75e-02	0.913000
SUMOylation of DNA methylation proteins	16	6.36e-01	-6.83e-02	0.916000
Post-translational protein modification	1276	6.37e-01	7.92e-03	0.916000
Diseases associated with O-glycosylation of proteins	62	6.38e-01	3.45e-02	0.917000
Diseases associated with glycosylation precursor biosynthesis	18	6.38e-01	6.40e-02	0.917000
DNA Double Strand Break Response	46	6.39e-01	4.00e-02	0.917000
Beta-catenin independent WNT signaling	142	6.40e-01	2.28e-02	0.917000
Digestion	16	6.41e-01	6.73e-02	0.917000
IRF3-mediated induction of type I IFN	13	6.41e-01	-7.46e-02	0.917000
MHC class II antigen presentation	94	6.42e-01	-2.77e-02	0.918000
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	79	6.44e-01	-3.01e-02	0.919000
Association of TriC/CCT with target proteins during biosynthesis	38	6.44e-01	-4.33e-02	0.919000
Homology Directed Repair	104	6.45e-01	2.61e-02	0.919000
Early Phase of HIV Life Cycle	13	6.46e-01	7.36e-02	0.919000
Miscellaneous transport and binding events	23	6.46e-01	-5.53e-02	0.919000
Inhibition of replication initiation of damaged DNA by RB1/E2F1	12	6.46e-01	7.65e-02	0.919000
ABC transporter disorders	75	6.47e-01	3.06e-02	0.919000
Post-translational modification: synthesis of GPI-anchored proteins	84	6.49e-01	2.87e-02	0.920000
DNA Damage/Telomere Stress Induced Senescence	41	6.49e-01	-4.10e-02	0.920000
GPVI-mediated activation cascade	32	6.51e-01	4.62e-02	0.921000
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	129	6.53e-01	-2.30e-02	0.923000
Condensation of Prophase Chromosomes	24	6.53e-01	-5.30e-02	0.923000
SUMOylation of RNA binding proteins	45	6.55e-01	3.85e-02	0.925000
MTOR signalling	38	6.57e-01	-4.17e-02	0.925000
Cohesin Loading onto Chromatin	10	6.57e-01	-8.11e-02	0.925000
Methylation	14	6.57e-01	-6.85e-02	0.925000
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	13	6.60e-01	7.06e-02	0.925000
Loss of Nlp from mitotic centrosomes	67	6.60e-01	-3.11e-02	0.925000
Loss of proteins required for interphase microtubule organization from the centrosome	67	6.60e-01	-3.11e-02	0.925000
Cellular response to heat stress	92	6.61e-01	2.65e-02	0.926000
RHO GTPases activate PKNs	44	6.63e-01	-3.80e-02	0.927000
ER to Golgi Anterograde Transport	126	6.64e-01	-2.24e-02	0.927000
Signaling by NODAL	17	6.64e-01	-6.09e-02	0.927000
E2F mediated regulation of DNA replication	21	6.64e-01	5.48e-02	0.927000
GLI3 is processed to GLI3R by the proteasome	57	6.65e-01	3.32e-02	0.927000
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	24	6.67e-01	-5.07e-02	0.928000
Gap junction trafficking and regulation	27	6.68e-01	-4.77e-02	0.928000
Interleukin-7 signaling	23	6.68e-01	5.16e-02	0.928000
Constitutive Signaling by EGFRvIII	14	6.69e-01	6.59e-02	0.928000
Signaling by EGFRvIII in Cancer	14	6.69e-01	6.59e-02	0.928000
Metabolism of Angiotensinogen to Angiotensins	18	6.70e-01	-5.81e-02	0.928000
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	19	6.70e-01	-5.64e-02	0.928000
Neurodegenerative Diseases	19	6.70e-01	-5.64e-02	0.928000
Prostacyclin signalling through prostacyclin receptor	18	6.71e-01	5.78e-02	0.928000
Generic Transcription Pathway	973	6.72e-01	-8.07e-03	0.928000
Transcriptional Regulation by TP53	341	6.72e-01	-1.33e-02	0.928000
Eicosanoid ligand-binding receptors	13	6.73e-01	-6.77e-02	0.928000
Signaling by NTRKs	132	6.75e-01	2.12e-02	0.930000
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	42	6.76e-01	3.73e-02	0.930000
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	30	6.79e-01	4.37e-02	0.930000
Acetylcholine Neurotransmitter Release Cycle	17	6.79e-01	5.81e-02	0.930000
Processing of Intronless Pre-mRNAs	18	6.79e-01	-5.64e-02	0.930000
Sodium/Calcium exchangers	11	6.80e-01	7.18e-02	0.930000
Degradation of beta-catenin by the destruction complex	82	6.80e-01	2.64e-02	0.930000
activated TAK1 mediates p38 MAPK activation	18	6.80e-01	5.61e-02	0.930000
CD28 co-stimulation	33	6.80e-01	-4.15e-02	0.930000
MET promotes cell motility	29	6.81e-01	-4.41e-02	0.930000
Peptide hormone metabolism	84	6.82e-01	-2.59e-02	0.930000
APC/C-mediated degradation of cell cycle proteins	85	6.83e-01	2.56e-02	0.930000
Regulation of mitotic cell cycle	85	6.83e-01	2.56e-02	0.930000
Amino acid transport across the plasma membrane	32	6.84e-01	4.16e-02	0.930000
Bile acid and bile salt metabolism	37	6.84e-01	-3.87e-02	0.930000
Signaling by FGFR4	38	6.85e-01	3.81e-02	0.930000
Signaling by PDGFRA extracellular domain mutants	12	6.86e-01	6.75e-02	0.930000
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants	12	6.86e-01	6.75e-02	0.930000
Vif-mediated degradation of APOBEC3G	51	6.87e-01	3.26e-02	0.931000
Synaptic adhesion-like molecules	21	6.88e-01	-5.06e-02	0.931000
Toll Like Receptor 9 (TLR9) Cascade	84	6.89e-01	-2.53e-02	0.931000
Interleukin-12 family signaling	49	6.89e-01	3.31e-02	0.931000
Surfactant metabolism	24	6.90e-01	-4.70e-02	0.931000
Glycolysis	68	6.91e-01	-2.79e-02	0.932000
SUMOylation of transcription factors	17	6.92e-01	-5.55e-02	0.932000
Attenuation phase	21	6.94e-01	-4.96e-02	0.934000
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases	14	6.96e-01	-6.02e-02	0.936000
Glutathione synthesis and recycling	12	6.99e-01	6.46e-02	0.938000
Glycogen synthesis	14	6.99e-01	5.98e-02	0.938000
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	16	7.01e-01	5.55e-02	0.939000
Inwardly rectifying K+ channels	33	7.03e-01	3.83e-02	0.940000
Defective B4GALT7 causes EDS, progeroid type	19	7.03e-01	5.04e-02	0.940000
Peroxisomal lipid metabolism	27	7.04e-01	-4.22e-02	0.940000
Signal attenuation	10	7.06e-01	-6.88e-02	0.940000
FLT3 Signaling	282	7.07e-01	1.30e-02	0.940000
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding	28	7.07e-01	-4.10e-02	0.940000
NCAM1 interactions	31	7.07e-01	3.90e-02	0.940000
Post NMDA receptor activation events	59	7.08e-01	-2.82e-02	0.940000
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	102	7.08e-01	2.15e-02	0.940000
RAF/MAP kinase cascade	268	7.08e-01	1.33e-02	0.940000
RHO GTPases activate KTN1	10	7.08e-01	-6.83e-02	0.940000
Protein localization	156	7.09e-01	-1.73e-02	0.940000
UCH proteinases	85	7.11e-01	2.33e-02	0.941000
TBC/RABGAPs	44	7.12e-01	3.22e-02	0.941000
Calcitonin-like ligand receptors	10	7.13e-01	6.71e-02	0.941000
Signaling by KIT in disease	20	7.13e-01	-4.75e-02	0.941000
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	20	7.13e-01	-4.75e-02	0.941000
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	12	7.13e-01	6.12e-02	0.941000
Nucleotide-like (purinergic) receptors	15	7.16e-01	-5.43e-02	0.941000
Alpha-protein kinase 1 signaling pathway	10	7.17e-01	-6.63e-02	0.941000
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	71	7.17e-01	2.49e-02	0.941000
Negative regulation of the PI3K/AKT network	109	7.17e-01	2.01e-02	0.941000
Nucleotide salvage	22	7.18e-01	-4.45e-02	0.941000
Signal regulatory protein family interactions	12	7.18e-01	-6.02e-02	0.941000
Phase 0 - rapid depolarisation	30	7.19e-01	3.79e-02	0.941000
ER-Phagosome pathway	80	7.20e-01	2.32e-02	0.941000
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	19	7.21e-01	4.73e-02	0.941000
Negative regulation of NOTCH4 signaling	52	7.21e-01	2.86e-02	0.941000
Reduction of cytosolic Ca++ levels	12	7.23e-01	-5.90e-02	0.941000
Class I MHC mediated antigen processing & presentation	345	7.24e-01	-1.11e-02	0.941000
VEGFA-VEGFR2 Pathway	91	7.25e-01	-2.13e-02	0.941000
Protein folding	94	7.26e-01	2.09e-02	0.941000
Retrograde neurotrophin signalling	14	7.27e-01	5.38e-02	0.941000
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	11	7.28e-01	-6.06e-02	0.941000
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	27	7.29e-01	3.86e-02	0.941000
MET activates RAS signaling	11	7.29e-01	-6.04e-02	0.941000
Lewis blood group biosynthesis	14	7.29e-01	5.34e-02	0.941000
Organic anion transporters	10	7.30e-01	-6.31e-02	0.941000
Telomere C-strand (Lagging Strand) Synthesis	33	7.30e-01	3.47e-02	0.941000
Assembly and cell surface presentation of NMDA receptors	23	7.31e-01	4.15e-02	0.941000
PI3K/AKT Signaling in Cancer	100	7.31e-01	1.99e-02	0.941000
Interleukin-35 Signalling	11	7.32e-01	-5.97e-02	0.941000
Initiation of Nuclear Envelope (NE) Reformation	16	7.34e-01	-4.90e-02	0.941000
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	17	7.35e-01	4.75e-02	0.941000
Signaling by Ligand-Responsive EGFR Variants in Cancer	17	7.35e-01	4.75e-02	0.941000
Transcriptional Regulation by E2F6	32	7.35e-01	3.46e-02	0.941000
HIV Infection	220	7.36e-01	1.32e-02	0.941000
Cytosolic iron-sulfur cluster assembly	13	7.37e-01	5.38e-02	0.941000
Beta-oxidation of very long chain fatty acids	10	7.37e-01	6.13e-02	0.941000
B-WICH complex positively regulates rRNA expression	39	7.38e-01	3.10e-02	0.941000
Regulation of PTEN mRNA translation	21	7.38e-01	4.22e-02	0.941000
RHO GTPases Activate WASPs and WAVEs	35	7.40e-01	-3.24e-02	0.941000
Lysosphingolipid and LPA receptors	14	7.40e-01	5.11e-02	0.941000
HCMV Early Events	67	7.40e-01	2.34e-02	0.941000
TNF signaling	43	7.41e-01	-2.91e-02	0.941000
CRMPs in Sema3A signaling	16	7.43e-01	-4.74e-02	0.941000
Norepinephrine Neurotransmitter Release Cycle	18	7.43e-01	4.47e-02	0.941000
Degradation of AXIN	52	7.43e-01	2.63e-02	0.941000
RAB GEFs exchange GTP for GDP on RABs	85	7.43e-01	2.06e-02	0.941000
Glutamate Neurotransmitter Release Cycle	24	7.43e-01	3.87e-02	0.941000
TNFR2 non-canonical NF-kB pathway	96	7.43e-01	1.94e-02	0.941000
Downregulation of ERBB2:ERBB3 signaling	12	7.44e-01	-5.45e-02	0.941000
Integrin cell surface interactions	60	7.44e-01	-2.44e-02	0.941000
Erythropoietin activates RAS	14	7.45e-01	5.03e-02	0.941000
Ion channel transport	170	7.45e-01	1.45e-02	0.941000
Neutrophil degranulation	449	7.45e-01	-8.96e-03	0.941000
Signaling by Activin	13	7.46e-01	5.19e-02	0.941000
RNA Polymerase II Pre-transcription Events	79	7.46e-01	-2.11e-02	0.941000
Negative regulation of FGFR2 signaling	32	7.47e-01	3.30e-02	0.941000
Thrombin signalling through proteinase activated receptors (PARs)	30	7.48e-01	3.39e-02	0.942000
Platelet calcium homeostasis	28	7.50e-01	3.48e-02	0.942000
Digestion and absorption	21	7.51e-01	-4.00e-02	0.942000
MAPK6/MAPK4 signaling	86	7.51e-01	-1.98e-02	0.942000
Signaling by Hippo	20	7.55e-01	-4.04e-02	0.942000
RNA Polymerase II Transcription Termination	63	7.55e-01	2.28e-02	0.942000
Termination of translesion DNA synthesis	30	7.55e-01	-3.29e-02	0.942000
Signaling by Receptor Tyrosine Kinases	468	7.55e-01	8.43e-03	0.942000
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	39	7.56e-01	-2.88e-02	0.942000
Ras activation upon Ca2+ influx through NMDA receptor	19	7.56e-01	4.12e-02	0.942000
RNA Pol II CTD phosphorylation and interaction with CE	25	7.56e-01	3.59e-02	0.942000
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	25	7.56e-01	3.59e-02	0.942000
RET signaling	39	7.57e-01	-2.86e-02	0.942000
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects	17	7.58e-01	-4.32e-02	0.942000
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	17	7.58e-01	-4.32e-02	0.942000
Protein methylation	14	7.58e-01	4.76e-02	0.942000
Disease	1436	7.59e-01	-4.86e-03	0.943000
Degradation of GLI1 by the proteasome	57	7.60e-01	2.34e-02	0.943000
Creation of C4 and C2 activators	38	7.62e-01	-2.84e-02	0.944000
Regulation of localization of FOXO transcription factors	11	7.62e-01	-5.27e-02	0.944000
Vesicle-mediated transport	640	7.63e-01	-7.01e-03	0.944000
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	11	7.63e-01	5.25e-02	0.944000
Apoptosis induced DNA fragmentation	12	7.65e-01	-4.98e-02	0.945000
Inhibition of DNA recombination at telomere	29	7.65e-01	-3.20e-02	0.945000
Toll Like Receptor 4 (TLR4) Cascade	114	7.68e-01	-1.60e-02	0.948000
VxPx cargo-targeting to cilium	21	7.70e-01	-3.69e-02	0.948000
TP53 Regulates Transcription of Caspase Activators and Caspases	10	7.70e-01	5.33e-02	0.948000
HCMV Late Events	61	7.70e-01	-2.16e-02	0.948000
Positive epigenetic regulation of rRNA expression	52	7.72e-01	-2.32e-02	0.949000
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	64	7.73e-01	-2.08e-02	0.950000
Prefoldin mediated transfer of substrate to CCT/TriC	25	7.78e-01	-3.25e-02	0.955000
Bicarbonate transporters	10	7.83e-01	5.04e-02	0.959000
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	22	7.83e-01	-3.39e-02	0.959000
Defective B3GAT3 causes JDSSDHD	19	7.85e-01	3.61e-02	0.959000
GABA receptor activation	58	7.85e-01	-2.07e-02	0.959000
Branched-chain amino acid catabolism	21	7.86e-01	-3.43e-02	0.959000
Processive synthesis on the C-strand of the telomere	18	7.86e-01	3.70e-02	0.959000
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation	10	7.86e-01	-4.96e-02	0.959000
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	13	7.89e-01	-4.28e-02	0.960000
Activation of NMDA receptors and postsynaptic events	71	7.89e-01	-1.83e-02	0.960000
Interleukin-12 signaling	39	7.91e-01	2.46e-02	0.960000
Unwinding of DNA	12	7.91e-01	-4.41e-02	0.960000
RIPK1-mediated regulated necrosis	24	7.92e-01	3.11e-02	0.960000
Regulated Necrosis	24	7.92e-01	3.11e-02	0.960000
Regulation of necroptotic cell death	24	7.92e-01	3.11e-02	0.960000
mitochondrial fatty acid beta-oxidation of saturated fatty acids	10	7.94e-01	4.76e-02	0.962000
Sealing of the nuclear envelope (NE) by ESCRT-III	24	7.95e-01	3.06e-02	0.963000
Protein-protein interactions at synapses	84	7.96e-01	1.63e-02	0.963000
Ca2+ pathway	60	7.97e-01	-1.92e-02	0.963000
Toll Like Receptor 3 (TLR3) Cascade	85	8.00e-01	-1.59e-02	0.966000
Physiological factors	12	8.01e-01	4.20e-02	0.966000
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	70	8.04e-01	1.72e-02	0.969000
eNOS activation	10	8.04e-01	4.53e-02	0.969000
Programmed Cell Death	172	8.05e-01	1.09e-02	0.969000
Aberrant regulation of mitotic cell cycle due to RB1 defects	35	8.08e-01	-2.38e-02	0.970000
Diseases of mitotic cell cycle	35	8.08e-01	-2.38e-02	0.970000
Phospholipid metabolism	203	8.12e-01	-9.71e-03	0.970000
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	45	8.12e-01	2.05e-02	0.970000
TP53 Regulates Transcription of Cell Cycle Genes	47	8.13e-01	2.00e-02	0.970000
Signaling by Non-Receptor Tyrosine Kinases	53	8.14e-01	1.87e-02	0.970000
Signaling by PTK6	53	8.14e-01	1.87e-02	0.970000
Competing endogenous RNAs (ceRNAs) regulate PTEN translation	15	8.14e-01	-3.50e-02	0.970000
Processing of SMDT1	14	8.16e-01	3.60e-02	0.970000
Acyl chain remodelling of PC	26	8.16e-01	-2.64e-02	0.970000
Inositol phosphate metabolism	47	8.17e-01	1.96e-02	0.970000
Transport of Mature mRNAs Derived from Intronless Transcripts	41	8.17e-01	2.09e-02	0.970000
Urea cycle	10	8.17e-01	-4.22e-02	0.970000
PIWI-interacting RNA (piRNA) biogenesis	26	8.18e-01	2.61e-02	0.970000
Deadenylation of mRNA	20	8.19e-01	2.96e-02	0.970000
Antiviral mechanism by IFN-stimulated genes	77	8.19e-01	1.51e-02	0.970000
Mitochondrial biogenesis	86	8.19e-01	-1.42e-02	0.970000
Voltage gated Potassium channels	41	8.20e-01	2.06e-02	0.970000
RNA Polymerase I Promoter Opening	13	8.21e-01	3.63e-02	0.970000
Mitochondrial calcium ion transport	21	8.21e-01	-2.86e-02	0.970000
The role of GTSE1 in G2/M progression after G2 checkpoint	55	8.22e-01	-1.75e-02	0.970000
Gamma-carboxylation of protein precursors	10	8.22e-01	-4.10e-02	0.970000
Regulation of insulin secretion	74	8.23e-01	-1.50e-02	0.970000
Negative regulation of NMDA receptor-mediated neuronal transmission	20	8.23e-01	2.88e-02	0.970000
Deactivation of the beta-catenin transactivating complex	39	8.24e-01	-2.06e-02	0.970000
APC/C:Cdc20 mediated degradation of mitotic proteins	73	8.28e-01	1.47e-02	0.970000
Glycogen breakdown (glycogenolysis)	14	8.29e-01	-3.34e-02	0.970000
APC/C:Cdc20 mediated degradation of Securin	65	8.29e-01	1.55e-02	0.970000
NOTCH2 intracellular domain regulates transcription	10	8.29e-01	3.95e-02	0.970000
RNA Polymerase I Transcription Initiation	44	8.29e-01	-1.88e-02	0.970000
Transport of Mature mRNA Derived from an Intronless Transcript	40	8.30e-01	1.96e-02	0.970000
Diseases associated with visual transduction	13	8.31e-01	3.43e-02	0.970000
Diseases of the neuronal system	13	8.31e-01	3.43e-02	0.970000
Retinoid cycle disease events	13	8.31e-01	3.43e-02	0.970000
FCGR3A-mediated phagocytosis	84	8.31e-01	-1.35e-02	0.970000
Leishmania phagocytosis	84	8.31e-01	-1.35e-02	0.970000
Parasite infection	84	8.31e-01	-1.35e-02	0.970000
CTLA4 inhibitory signaling	21	8.31e-01	-2.68e-02	0.970000
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	31	8.33e-01	-2.19e-02	0.970000
ISG15 antiviral mechanism	69	8.33e-01	1.47e-02	0.970000
Downregulation of SMAD2/3:SMAD4 transcriptional activity	22	8.33e-01	2.59e-02	0.970000
Extension of Telomeres	50	8.35e-01	1.71e-02	0.971000
Removal of the Flap Intermediate from the C-strand	16	8.37e-01	2.98e-02	0.972000
Neurotransmitter release cycle	51	8.37e-01	-1.66e-02	0.972000
Negative regulation of FGFR4 signaling	28	8.40e-01	-2.21e-02	0.973000
BBSome-mediated cargo-targeting to cilium	22	8.40e-01	2.49e-02	0.973000
Aggrephagy	20	8.41e-01	-2.60e-02	0.973000
Cytosolic sensors of pathogen-associated DNA	55	8.41e-01	-1.57e-02	0.973000
Dissolution of Fibrin Clot	11	8.42e-01	3.48e-02	0.973000
Late Phase of HIV Life Cycle	130	8.44e-01	1.00e-02	0.974000
Signaling by Nuclear Receptors	235	8.44e-01	-7.48e-03	0.974000
A tetrasaccharide linker sequence is required for GAG synthesis	25	8.44e-01	-2.27e-02	0.974000
MAPK family signaling cascades	312	8.47e-01	-6.38e-03	0.975000
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	16	8.47e-01	-2.78e-02	0.975000
Role of phospholipids in phagocytosis	52	8.49e-01	1.52e-02	0.975000
Chaperonin-mediated protein folding	88	8.49e-01	-1.17e-02	0.975000
AURKA Activation by TPX2	70	8.50e-01	-1.31e-02	0.975000
Visual phototransduction	92	8.51e-01	1.13e-02	0.975000
Transport of small molecules	687	8.53e-01	-4.17e-03	0.975000
HIV Life Cycle	142	8.54e-01	8.97e-03	0.975000
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)	10	8.54e-01	3.36e-02	0.975000
Pyruvate metabolism and Citric Acid (TCA) cycle	53	8.54e-01	-1.46e-02	0.975000
PTEN Regulation	146	8.54e-01	8.81e-03	0.975000
Macroautophagy	108	8.55e-01	-1.02e-02	0.975000
DNA strand elongation	31	8.55e-01	-1.90e-02	0.975000
Activation of the phototransduction cascade	10	8.55e-01	3.33e-02	0.975000
P2Y receptors	11	8.56e-01	3.17e-02	0.975000
Basigin interactions	25	8.56e-01	-2.09e-02	0.975000
Infection with Mycobacterium tuberculosis	26	8.57e-01	-2.04e-02	0.975000
Mitotic G2-G2/M phases	178	8.58e-01	7.80e-03	0.975000
Signaling by Interleukins	413	8.58e-01	-5.14e-03	0.975000
Polymerase switching on the C-strand of the telomere	25	8.61e-01	2.02e-02	0.977000
Signalling to RAS	19	8.62e-01	2.31e-02	0.977000
Apoptotic execution phase	51	8.62e-01	-1.41e-02	0.977000
mRNA decay by 3' to 5' exoribonuclease	16	8.62e-01	-2.50e-02	0.977000
mRNA 3'-end processing	55	8.63e-01	1.34e-02	0.977000
Mitochondrial Fatty Acid Beta-Oxidation	36	8.64e-01	1.65e-02	0.977000
Reproduction	87	8.64e-01	-1.06e-02	0.977000
Presynaptic depolarization and calcium channel opening	12	8.67e-01	2.80e-02	0.977000
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	19	8.68e-01	2.20e-02	0.977000
Metabolism of amine-derived hormones	17	8.68e-01	-2.32e-02	0.977000
Regulation of TP53 Activity	149	8.69e-01	-7.85e-03	0.977000
Caspase activation via Dependence Receptors in the absence of ligand	10	8.69e-01	3.02e-02	0.977000
FCERI mediated Ca+2 mobilization	55	8.70e-01	1.28e-02	0.977000
MAPK1/MAPK3 signaling	274	8.72e-01	5.67e-03	0.977000
Processing and activation of SUMO	10	8.72e-01	2.94e-02	0.977000
Netrin-1 signaling	49	8.73e-01	-1.32e-02	0.977000
Mismatch Repair	14	8.74e-01	2.44e-02	0.977000
SARS-CoV-2 Infection	64	8.74e-01	-1.14e-02	0.977000
Stimuli-sensing channels	97	8.75e-01	9.26e-03	0.977000
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	86	8.75e-01	-9.83e-03	0.977000
Toll Like Receptor 2 (TLR2) Cascade	86	8.75e-01	-9.83e-03	0.977000
Toll Like Receptor TLR1:TLR2 Cascade	86	8.75e-01	-9.83e-03	0.977000
Toll Like Receptor TLR6:TLR2 Cascade	86	8.75e-01	-9.83e-03	0.977000
Aberrant regulation of mitotic exit in cancer due to RB1 defects	19	8.75e-01	-2.08e-02	0.977000
trans-Golgi Network Vesicle Budding	70	8.78e-01	-1.06e-02	0.979000
Regulation of TP53 Expression and Degradation	34	8.79e-01	1.51e-02	0.979000
ABC transporters in lipid homeostasis	17	8.80e-01	2.12e-02	0.979000
NOD1/2 Signaling Pathway	30	8.82e-01	1.57e-02	0.979000
Infectious disease	757	8.83e-01	-3.16e-03	0.979000
Transcriptional Regulation by MECP2	57	8.83e-01	1.13e-02	0.979000
Inactivation of APC/C via direct inhibition of the APC/C complex	20	8.84e-01	-1.88e-02	0.979000
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	20	8.84e-01	-1.88e-02	0.979000
Interleukin-4 and Interleukin-13 signaling	102	8.84e-01	-8.33e-03	0.979000
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	10	8.85e-01	2.64e-02	0.979000
Activation of RAC1	13	8.87e-01	-2.27e-02	0.979000
Termination of O-glycan biosynthesis	19	8.88e-01	1.87e-02	0.979000
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	16	8.88e-01	2.03e-02	0.979000
NCAM signaling for neurite out-growth	52	8.88e-01	1.12e-02	0.979000
Organelle biogenesis and maintenance	265	8.89e-01	-4.97e-03	0.979000
Receptor-type tyrosine-protein phosphatases	19	8.90e-01	1.83e-02	0.979000
Amyloid fiber formation	56	8.90e-01	-1.07e-02	0.979000
Meiosis	67	8.91e-01	9.71e-03	0.979000
Incretin synthesis, secretion, and inactivation	22	8.91e-01	1.68e-02	0.979000
Regulation of TP53 Degradation	33	8.92e-01	-1.36e-02	0.979000
MyD88-independent TLR4 cascade	87	8.92e-01	-8.39e-03	0.979000
TRIF(TICAM1)-mediated TLR4 signaling	87	8.92e-01	-8.39e-03	0.979000
Leading Strand Synthesis	13	8.93e-01	2.14e-02	0.979000
Polymerase switching	13	8.93e-01	2.14e-02	0.979000
DAP12 interactions	38	8.96e-01	1.23e-02	0.980000
RHO GTPase Effectors	249	8.97e-01	4.77e-03	0.981000
G-protein beta:gamma signalling	31	8.99e-01	-1.32e-02	0.982000
Regulation of signaling by NODAL	10	9.00e-01	-2.29e-02	0.982000
COPI-mediated anterograde transport	77	9.01e-01	8.23e-03	0.982000
Activation of Ca-permeable Kainate Receptor	10	9.01e-01	2.27e-02	0.982000
Ionotropic activity of kainate receptors	10	9.01e-01	2.27e-02	0.982000
G2/M DNA damage checkpoint	64	9.02e-01	8.92e-03	0.982000
Nonhomologous End-Joining (NHEJ)	40	9.05e-01	1.09e-02	0.985000
Pyruvate metabolism	29	9.07e-01	1.25e-02	0.986000
Formation of Incision Complex in GG-NER	42	9.09e-01	-1.02e-02	0.986000
Ion homeostasis	47	9.09e-01	-9.63e-03	0.986000
Retrograde transport at the Trans-Golgi-Network	46	9.09e-01	-9.71e-03	0.986000
MicroRNA (miRNA) biogenesis	24	9.10e-01	-1.33e-02	0.986000
Gamma carboxylation, hypusine formation and arylsulfatase activation	37	9.12e-01	1.06e-02	0.987000
Apoptosis	162	9.12e-01	5.03e-03	0.987000
Processing of Capped Intronless Pre-mRNA	26	9.13e-01	-1.24e-02	0.987000
LGI-ADAM interactions	14	9.15e-01	-1.65e-02	0.988000
Glycogen metabolism	25	9.16e-01	-1.21e-02	0.988000
Telomere Maintenance	73	9.17e-01	-7.06e-03	0.988000
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	13	9.17e-01	-1.66e-02	0.988000
Translation of Replicase and Assembly of the Replication Transcription Complex	12	9.18e-01	1.71e-02	0.988000
Class C/3 (Metabotropic glutamate/pheromone receptors)	31	9.19e-01	-1.05e-02	0.988000
Intraflagellar transport	38	9.20e-01	-9.42e-03	0.988000
Activation of Matrix Metalloproteinases	30	9.21e-01	1.05e-02	0.988000
MET activates RAP1 and RAC1	11	9.21e-01	-1.72e-02	0.988000
Transport of vitamins, nucleosides, and related molecules	42	9.23e-01	8.64e-03	0.988000
TP53 Regulates Transcription of Cell Death Genes	34	9.24e-01	9.47e-03	0.988000
HDR through MMEJ (alt-NHEJ)	10	9.24e-01	-1.73e-02	0.988000
Regulation of mRNA stability by proteins that bind AU-rich elements	86	9.25e-01	-5.89e-03	0.988000
Negative regulation of FGFR1 signaling	30	9.26e-01	-9.86e-03	0.988000
Oxidative Stress Induced Senescence	69	9.26e-01	6.51e-03	0.988000
Transport to the Golgi and subsequent modification	154	9.30e-01	4.13e-03	0.988000
Neddylation	226	9.30e-01	-3.37e-03	0.988000
G2/M Transition	176	9.31e-01	3.81e-03	0.988000
SIRT1 negatively regulates rRNA expression	18	9.32e-01	1.16e-02	0.988000
Regulation of KIT signaling	16	9.33e-01	-1.22e-02	0.988000
Misspliced GSK3beta mutants stabilize beta-catenin	14	9.33e-01	1.30e-02	0.988000
S33 mutants of beta-catenin aren't phosphorylated	14	9.33e-01	1.30e-02	0.988000
S37 mutants of beta-catenin aren't phosphorylated	14	9.33e-01	1.30e-02	0.988000
S45 mutants of beta-catenin aren't phosphorylated	14	9.33e-01	1.30e-02	0.988000
T41 mutants of beta-catenin aren't phosphorylated	14	9.33e-01	1.30e-02	0.988000
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex	14	9.33e-01	1.30e-02	0.988000
Detoxification of Reactive Oxygen Species	33	9.33e-01	8.46e-03	0.988000
Signaling by Erythropoietin	25	9.33e-01	9.69e-03	0.988000
Gap junction trafficking	25	9.34e-01	9.62e-03	0.988000
AUF1 (hnRNP D0) binds and destabilizes mRNA	52	9.36e-01	-6.45e-03	0.989000
Organic cation/anion/zwitterion transport	12	9.36e-01	1.33e-02	0.989000
Diseases of programmed cell death	25	9.38e-01	9.03e-03	0.990000
p38MAPK events	13	9.39e-01	1.22e-02	0.991000
TRAF6 mediated NF-kB activation	19	9.40e-01	-9.94e-03	0.991000
Interleukin-1 signaling	95	9.40e-01	4.44e-03	0.991000
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	74	9.44e-01	4.76e-03	0.992000
Anchoring of the basal body to the plasma membrane	94	9.44e-01	4.19e-03	0.992000
Hedgehog 'off' state	96	9.44e-01	-4.12e-03	0.992000
TP53 Regulates Metabolic Genes	83	9.45e-01	4.36e-03	0.992000
TAK1 activates NFkB by phosphorylation and activation of IKKs complex	23	9.46e-01	8.22e-03	0.992000
Synthesis, secretion, and deacylation of Ghrelin	18	9.46e-01	9.28e-03	0.992000
G beta:gamma signalling through CDC42	19	9.49e-01	-8.41e-03	0.995000
Activation of the TFAP2 (AP-2) family of transcription factors	11	9.51e-01	1.07e-02	0.996000
Growth hormone receptor signaling	24	9.52e-01	-7.11e-03	0.997000
MAP3K8 (TPL2)-dependent MAPK1/3 activation	15	9.52e-01	8.89e-03	0.997000
SUMO E3 ligases SUMOylate target proteins	158	9.54e-01	-2.69e-03	0.997000
Unblocking of NMDA receptors, glutamate binding and activation	20	9.56e-01	7.15e-03	0.999000
Signaling by FGFR4 in disease	11	9.57e-01	-9.44e-03	0.999000
Metabolism of RNA	632	9.57e-01	-1.25e-03	0.999000
Telomere Extension By Telomerase	23	9.58e-01	6.35e-03	0.999000
Cardiac conduction	116	9.59e-01	-2.77e-03	0.999000
Acyl chain remodelling of PE	26	9.60e-01	5.64e-03	0.999000
Platelet homeostasis	81	9.61e-01	3.18e-03	0.999000
TRAF6-mediated induction of TAK1 complex within TLR4 complex	12	9.61e-01	8.11e-03	0.999000
FCGR activation	39	9.62e-01	-4.41e-03	0.999000
Apoptotic cleavage of cellular proteins	38	9.63e-01	-4.35e-03	0.999000
Citric acid cycle (TCA cycle)	22	9.64e-01	-5.48e-03	0.999000
Formation of ATP by chemiosmotic coupling	15	9.65e-01	-6.64e-03	0.999000
Formation of the Early Elongation Complex	31	9.68e-01	4.16e-03	0.999000
Formation of the HIV-1 Early Elongation Complex	31	9.68e-01	4.16e-03	0.999000
Polo-like kinase mediated events	15	9.70e-01	-5.56e-03	0.999000
Synthesis of bile acids and bile salts	29	9.71e-01	-3.91e-03	0.999000
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	71	9.71e-01	-2.45e-03	0.999000
RNA Polymerase I Promoter Clearance	56	9.72e-01	2.69e-03	0.999000
RNA Polymerase I Transcription	56	9.72e-01	2.69e-03	0.999000
Plasma lipoprotein clearance	32	9.72e-01	-3.54e-03	0.999000
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)	13	9.72e-01	5.53e-03	0.999000
Lysosome Vesicle Biogenesis	34	9.73e-01	3.40e-03	0.999000
SUMOylation	164	9.73e-01	1.51e-03	0.999000
Cytosolic sulfonation of small molecules	23	9.74e-01	-3.90e-03	0.999000
Oncogene Induced Senescence	30	9.74e-01	-3.40e-03	0.999000
Signalling to ERKs	33	9.77e-01	2.96e-03	0.999000
Signaling by MET	66	9.79e-01	-1.86e-03	0.999000
PECAM1 interactions	11	9.80e-01	4.46e-03	0.999000
APC-Cdc20 mediated degradation of Nek2A	24	9.80e-01	2.99e-03	0.999000
Lagging Strand Synthesis	19	9.81e-01	-3.10e-03	0.999000
Estrogen-dependent gene expression	96	9.83e-01	-1.28e-03	0.999000
Signaling by FGFR2 IIIa TM	17	9.83e-01	3.02e-03	0.999000
COPI-independent Golgi-to-ER retrograde traffic	33	9.84e-01	1.98e-03	0.999000
Triglyceride biosynthesis	13	9.88e-01	-2.38e-03	0.999000
Signaling by SCF-KIT	42	9.88e-01	-1.32e-03	0.999000
Packaging Of Telomere Ends	16	9.88e-01	-2.12e-03	0.999000
Regulation of signaling by CBL	18	9.89e-01	-1.82e-03	0.999000
AMER1 mutants destabilize the destruction complex	13	9.90e-01	-1.95e-03	0.999000
APC truncation mutants have impaired AXIN binding	13	9.90e-01	-1.95e-03	0.999000
AXIN missense mutants destabilize the destruction complex	13	9.90e-01	-1.95e-03	0.999000
AXIN mutants destabilize the destruction complex, activating WNT signaling	13	9.90e-01	-1.95e-03	0.999000
Truncations of AMER1 destabilize the destruction complex	13	9.90e-01	-1.95e-03	0.999000
truncated APC mutants destabilize the destruction complex	13	9.90e-01	-1.95e-03	0.999000
SUMOylation of immune response proteins	10	9.91e-01	2.07e-03	0.999000
Cell recruitment (pro-inflammatory response)	23	9.91e-01	-1.30e-03	0.999000
Purinergic signaling in leishmaniasis infection	23	9.91e-01	-1.30e-03	0.999000
Cilium Assembly	179	9.92e-01	-4.51e-04	0.999000
PIP3 activates AKT signaling	269	9.92e-01	-3.58e-04	0.999000
Na+/Cl- dependent neurotransmitter transporters	18	9.92e-01	-1.34e-03	0.999000
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	19	9.93e-01	1.18e-03	0.999000
Acyl chain remodelling of PS	21	9.93e-01	1.04e-03	0.999000
Signaling by WNT in cancer	33	9.94e-01	-8.16e-04	0.999000
FGFR2 alternative splicing	23	9.94e-01	-8.73e-04	0.999000
ATF6 (ATF6-alpha) activates chaperone genes	10	9.95e-01	1.22e-03	0.999000
EPHB-mediated forward signaling	33	9.96e-01	5.38e-04	0.999000
Blood group systems biosynthesis	18	9.96e-01	-7.06e-04	0.999000
Carboxyterminal post-translational modifications of tubulin	33	9.96e-01	4.66e-04	0.999000
G0 and Early G1	27	9.97e-01	4.56e-04	0.999000
Golgi Cisternae Pericentriolar Stack Reorganization	12	9.97e-01	-6.75e-04	0.999000
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	13	9.97e-01	5.80e-04	0.999000
Synthesis of glycosylphosphatidylinositol (GPI)	17	9.98e-01	3.52e-04	0.999000
Diseases of metabolism	230	9.99e-01	-7.18e-05	0.999000
mRNA Splicing - Minor Pathway	48	1.00e+00	-3.13e-05	1.000000

---

Detailed Gene set reports

Xenobiotics

Xenobiotics

	1408
set	Xenobiotics
setSize	20
pANOVA	1.64e-07
s.dist	-0.676
p.adjustANOVA	0.000238

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CYP2A13	-9057.0
CYP2A6	-9057.0
CYP2A7	-9057.0
CYP2D6	-9035.5
CYP2E1	-8999.0
CYP3A4	-8991.0
CYP3A43	-8991.0
CYP3A5	-8991.0
CYP3A7	-8991.0
ARNT	-8977.0
AHRR	-8688.0
CYP2F1	-8491.0
CYP2C18	-7923.5
CYP1A2	-6798.0
CYP2W1	-3941.0
CYP2S1	-1638.0
CYP2J2	-235.0
CYP1A1	359.0
ARNT2	1509.0
AHR	2943.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CYP2A13	-9057.0
CYP2A6	-9057.0
CYP2A7	-9057.0
CYP2D6	-9035.5
CYP2E1	-8999.0
CYP3A4	-8991.0
CYP3A43	-8991.0
CYP3A5	-8991.0
CYP3A7	-8991.0
ARNT	-8977.0
AHRR	-8688.0
CYP2F1	-8491.0
CYP2C18	-7923.5
CYP1A2	-6798.0
CYP2W1	-3941.0
CYP2S1	-1638.0
CYP2J2	-235.0
CYP1A1	359.0
ARNT2	1509.0
AHR	2943.5

---

Plasma lipoprotein remodeling

Plasma lipoprotein remodeling

	884
set	Plasma lipoprotein remodeling
setSize	31
pANOVA	1.95e-06
s.dist	-0.494
p.adjustANOVA	0.00141

Top enriched genes

Top 20 genes

GeneID	Gene Rank
APOC3	-8904.0
CIDEC	-8897.0
ABCG1	-8866.0
APOE	-8836.0
MBTPS2	-8761.0
APOA5	-8466.0
MBTPS1	-7804.0
APOC2	-7531.5
APOA2	-7400.0
APOF	-7268.0
CREB3L3	-7263.0
LCAT	-6772.0
APOA4	-6758.0
ANGPTL3	-6400.0
FURIN	-6399.0
ANGPTL4	-6243.0
LIPC	-5932.0
LMF2	-5317.0
LIPG	-5216.0
FGF21	-5116.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
APOC3	-8904.0
CIDEC	-8897.0
ABCG1	-8866.0
APOE	-8836.0
MBTPS2	-8761.0
APOA5	-8466.0
MBTPS1	-7804.0
APOC2	-7531.5
APOA2	-7400.0
APOF	-7268.0
CREB3L3	-7263.0
LCAT	-6772.0
APOA4	-6758.0
ANGPTL3	-6400.0
FURIN	-6399.0
ANGPTL4	-6243.0
LIPC	-5932.0
LMF2	-5317.0
LIPG	-5216.0
FGF21	-5116.0
ANGPTL8	-4094.0
LPA	-3826.0
GPIHBP1	-3404.0
LPL	-2467.0
PLTP	-2003.0
APOA1	-547.0
APOB	573.0
PCSK5	3308.0
PCSK6	4262.0
LMF1	4677.0
ALB	7970.0

---

Fatty acids

Fatty acids

	414
set	Fatty acids
setSize	14
pANOVA	4.06e-06
s.dist	-0.711
p.adjustANOVA	0.00182

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CYP2A13	-9057.0
CYP2A7	-9057.0
CYP4F8	-9040.0
CYP2D6	-9035.5
CYP2F1	-8491.0
CYP4F2	-8108.0
CYP4A11	-7728.5
CYP4A22	-7728.5
CYP4F11	-7728.5
CYP4F12	-7728.5
CYP4B1	-6651.0
CYP4F3	-4081.0
CYP2J2	-235.0
CYP4F22	4080.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CYP2A13	-9057.0
CYP2A7	-9057.0
CYP4F8	-9040.0
CYP2D6	-9035.5
CYP2F1	-8491.0
CYP4F2	-8108.0
CYP4A11	-7728.5
CYP4A22	-7728.5
CYP4F11	-7728.5
CYP4F12	-7728.5
CYP4B1	-6651.0
CYP4F3	-4081.0
CYP2J2	-235.0
CYP4F22	4080.0

---

Collagen formation

Collagen formation

	212
set	Collagen formation
setSize	80
pANOVA	5.04e-06
s.dist	0.295
p.adjustANOVA	0.00182

Top enriched genes

Top 20 genes

GeneID	Gene Rank
COL1A2	8941
LOX	8924
LAMC2	8913
COL17A1	8726
COL11A2	8584
COL13A1	8432
P4HA3	8415
COL16A1	8364
LOXL2	8342
PCOLCE	8334
P4HA2	8315
SERPINH1	8239
ADAMTS2	8086
COL8A2	8066
COL1A1	7952
COL9A1	7923
MMP3	7551
MMP9	7518
COL12A1	7478
ADAMTS3	7408

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
COL1A2	8941
LOX	8924
LAMC2	8913
COL17A1	8726
COL11A2	8584
COL13A1	8432
P4HA3	8415
COL16A1	8364
LOXL2	8342
PCOLCE	8334
P4HA2	8315
SERPINH1	8239
ADAMTS2	8086
COL8A2	8066
COL1A1	7952
COL9A1	7923
MMP3	7551
MMP9	7518
COL12A1	7478
ADAMTS3	7408
BMP1	7235
COL5A1	7233
COL8A1	7168
COL2A1	7114
LOXL1	7085
PCOLCE2	6917
PPIB	6887
COL11A1	6757
LAMB3	6421
TLL2	6245
LOXL4	6012
P3H2	5928
DST	5910
P4HA1	5544
COL14A1	5203
ADAMTS14	4789
COL6A2	4759
PLOD3	4609
TLL1	4083
MMP20	3915
COL3A1	3907
P3H3	3882
COL26A1	3774
COL6A1	3749
COL4A6	3630
COL23A1	3188
COL5A2	3064
CRTAP	2918
MMP7	2736
CTSS	2396
P3H1	2050
CD151	1741
COL27A1	951
PLOD1	638
COL19A1	452
COL4A3	385
MMP13	-756
COL5A3	-869
COLGALT1	-898
CTSB	-1337
LOXL3	-2045
P4HB	-2423
COL28A1	-2995
COL4A5	-3059
COL6A6	-3769
COL4A1	-4472
CTSV	-4546
COL4A2	-4819
COL18A1	-5131
COL6A5	-5779
ITGA6	-5895
COL15A1	-6154
LAMA3	-6177
ITGB4	-6853
PXDN	-7676
COL9A2	-7743
COLGALT2	-7793
PLOD2	-7959
COL25A1	-8293
PLEC	-9079

---

Collagen biosynthesis and modifying enzymes

Collagen biosynthesis and modifying enzymes

	209
set	Collagen biosynthesis and modifying enzymes
setSize	58
pANOVA	7.24e-06
s.dist	0.341
p.adjustANOVA	0.0021

Top enriched genes

Top 20 genes

GeneID	Gene Rank
COL1A2	8941
COL17A1	8726
COL11A2	8584
COL13A1	8432
P4HA3	8415
COL16A1	8364
PCOLCE	8334
P4HA2	8315
SERPINH1	8239
ADAMTS2	8086
COL8A2	8066
COL1A1	7952
COL9A1	7923
COL12A1	7478
ADAMTS3	7408
BMP1	7235
COL5A1	7233
COL8A1	7168
COL2A1	7114
PCOLCE2	6917

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
COL1A2	8941
COL17A1	8726
COL11A2	8584
COL13A1	8432
P4HA3	8415
COL16A1	8364
PCOLCE	8334
P4HA2	8315
SERPINH1	8239
ADAMTS2	8086
COL8A2	8066
COL1A1	7952
COL9A1	7923
COL12A1	7478
ADAMTS3	7408
BMP1	7235
COL5A1	7233
COL8A1	7168
COL2A1	7114
PCOLCE2	6917
PPIB	6887
COL11A1	6757
TLL2	6245
P3H2	5928
P4HA1	5544
COL14A1	5203
ADAMTS14	4789
COL6A2	4759
PLOD3	4609
TLL1	4083
COL3A1	3907
P3H3	3882
COL26A1	3774
COL6A1	3749
COL4A6	3630
COL23A1	3188
COL5A2	3064
CRTAP	2918
P3H1	2050
COL27A1	951
PLOD1	638
COL19A1	452
COL4A3	385
COL5A3	-869
COLGALT1	-898
P4HB	-2423
COL28A1	-2995
COL4A5	-3059
COL6A6	-3769
COL4A1	-4472
COL4A2	-4819
COL18A1	-5131
COL6A5	-5779
COL15A1	-6154
COL9A2	-7743
COLGALT2	-7793
PLOD2	-7959
COL25A1	-8293

---

NR1H2 and NR1H3-mediated signaling

NR1H2 and NR1H3-mediated signaling

	751
set	NR1H2 and NR1H3-mediated signaling
setSize	48
pANOVA	3.3e-05
s.dist	-0.346
p.adjustANOVA	0.00797

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PLIN1	-9007.0
APOC1	-8963.0
ABCG1	-8866.0
APOE	-8836.0
PCK1	-8806.0
TNRC6B	-8577.0
NCOR2	-8506.0
KDM4A	-8470.5
AGO4	-8424.0
NCOR1	-8129.0
RXRB	-7956.0
FASN	-7594.0
APOC2	-7531.5
NR1H3	-7384.0
NCOA1	-6733.0
ANGPTL3	-6400.0
EEPD1	-6385.0
ABCA1	-6097.0
AGO1	-5804.0
GPS2	-5694.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PLIN1	-9007.0
APOC1	-8963.0
ABCG1	-8866.0
APOE	-8836.0
PCK1	-8806.0
TNRC6B	-8577.0
NCOR2	-8506.0
KDM4A	-8470.5
AGO4	-8424.0
NCOR1	-8129.0
RXRB	-7956.0
FASN	-7594.0
APOC2	-7531.5
NR1H3	-7384.0
NCOA1	-6733.0
ANGPTL3	-6400.0
EEPD1	-6385.0
ABCA1	-6097.0
AGO1	-5804.0
GPS2	-5694.0
TNRC6C	-5527.0
MIR144	-5518.0
AGO2	-5246.0
RXRA	-5221.0
TBL1XR1	-5183.0
MYLIP	-5032.0
NR1H2	-4967.0
SREBF1	-4592.0
APOD	-4213.0
KDM1B	-3115.0
SCD	-2989.0
KDM3A	-2751.0
ABCG5	-2445.0
FABP6	-2049.0
PLTP	-2003.0
APOC4	-1990.0
MIR33A	-1119.0
EP300	1591.0
TBL1X	1601.5
HDAC3	5550.0
MIR26A1	5951.0
MOV10	6056.0
ABCG8	6224.0
MIR26A2	6542.0
AGO3	7448.0
TNRC6A	7675.0
NRIP1	8401.0
KDM1A	8614.0

---

Phase I - Functionalization of compounds

Phase I - Functionalization of compounds

	870
set	Phase I - Functionalization of compounds
setSize	91
pANOVA	4.09e-05
s.dist	-0.249
p.adjustANOVA	0.00846

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CES2	-9059.0
CYP2A13	-9057.0
CYP2A6	-9057.0
CYP2A7	-9057.0
CYP4F8	-9040.0
CYP2D6	-9035.5
CYP2E1	-8999.0
CYP3A4	-8991.0
CYP3A43	-8991.0
CYP3A5	-8991.0
CYP3A7	-8991.0
ARNT	-8977.0
CYB5B	-8813.0
CES1	-8705.0
AHRR	-8688.0
CYP2F1	-8491.0
CYP46A1	-8248.0
CYP4F2	-8108.0
CYP2C18	-7923.5
ALDH2	-7822.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CES2	-9059.0
CYP2A13	-9057.0
CYP2A6	-9057.0
CYP2A7	-9057.0
CYP4F8	-9040.0
CYP2D6	-9035.5
CYP2E1	-8999.0
CYP3A4	-8991.0
CYP3A43	-8991.0
CYP3A5	-8991.0
CYP3A7	-8991.0
ARNT	-8977.0
CYB5B	-8813.0
CES1	-8705.0
AHRR	-8688.0
CYP2F1	-8491.0
CYP46A1	-8248.0
CYP4F2	-8108.0
CYP2C18	-7923.5
ALDH2	-7822.5
CYP4A11	-7728.5
CYP4A22	-7728.5
CYP4F11	-7728.5
CYP4F12	-7728.5
ACSS1	-7584.0
FMO2	-7251.0
CMBL	-7011.0
FMO3	-6965.0
CYP1A2	-6798.0
NCOA1	-6733.0
CYP4B1	-6651.0
MAOA	-6052.0
AIP	-5975.0
POR	-5945.0
CYP26B1	-5722.0
SMOX	-5524.0
RXRA	-5221.0
NCOA2	-5184.0
CYB5R3	-5151.0
ALDH1B1	-4681.0
CYP24A1	-4478.0
CYP4F3	-4081.0
CYP2W1	-3941.0
ALDH1A1	-3766.0
CYP27B1	-3689.0
MAOB	-3229.0
HSP90AB1	-3151.0
EPHX1	-2961.0
CYP4V2	-2726.0
ADH7	-2536.0
ACSS2	-2133.0
PAOX	-1652.5
CYP2S1	-1638.0
CBR3	-1562.5
CYP2R1	-1234.0
CYP2J2	-235.0
CYP1A1	359.0
AADAC	480.0
AOC3	784.0
CYP51A1	1117.0
CYP27A1	1302.0
CYP8B1	1456.0
AOC1	1466.0
ARNT2	1509.0
CYP19A1	1797.0
CYP21A2	2301.0
CYP2U1	2375.0
ADH5	2725.0
AHR	2943.5
CYP7A1	3065.0
POMC	3261.0
CYP4F22	4080.0
MTARC2	4279.0
PTGES3	4369.0
FDX2	4488.5
FDX1	4538.0
NR1H4	4600.0
BPHL	4818.0
ALDH3A1	4826.0
PTGS1	4865.0
CYP7B1	4950.0
MTARC1	5152.5
FMO1	5603.0
TBXAS1	5711.0
CYP26A1	5725.0
CYP39A1	6053.0
CYP11A1	6250.0
NQO2	6527.0
CYP26C1	7324.0
CYP1B1	8673.0
PTGIS	8898.0

---

Translation

Translation

	1345
set	Translation
setSize	262
pANOVA	5.52e-05
s.dist	0.145
p.adjustANOVA	0.00999

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL13A	8957
RPL3	8943
MRPS14	8926
RPS15A	8920
RPL29	8919
RPS16	8907
RPL6	8889
MRPS24	8562
MRPL1	8558
MRPS28	8557
MRPS18B	8556
MRPL36	8464
SSR2	8391
TRAM1	8349
PTCD3	8263
NARS1	8198
EIF3E	8145
MARS2	8097
PPA2	8059
RPL37	8039

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL13A	8957.0
RPL3	8943.0
MRPS14	8926.0
RPS15A	8920.0
RPL29	8919.0
RPS16	8907.0
RPL6	8889.0
MRPS24	8562.0
MRPL1	8558.0
MRPS28	8557.0
MRPS18B	8556.0
MRPL36	8464.0
SSR2	8391.0
TRAM1	8349.0
PTCD3	8263.0
NARS1	8198.0
EIF3E	8145.0
MARS2	8097.0
PPA2	8059.0
RPL37	8039.0
SRP9	7935.0
NARS2	7888.0
DAP3	7885.0
EIF2B1	7876.0
EPRS1	7828.0
TARS1	7731.0
GARS1	7641.0
MRPS35	7617.0
CHCHD1	7563.0
HARS2	7559.0
PARS2	7528.0
RPL30	7370.0
RPS27A	7369.0
IARS1	7272.0
PPA1	7256.0
MRPL2	7250.0
RPL7A	7100.0
RPS23	7033.0
MRPL17	7018.0
SEC61A1	6972.0
MRPL14	6867.0
WARS1	6861.0
HARS1	6860.0
EIF4A2	6640.0
RPS18	6557.0
RPLP2	6538.0
RPL10L	6517.0
EARS2	6509.0
RPS15	6242.0
RPS5	6228.0
AIMP1	6191.0
MRPL24	6176.0
MRPL42	6072.0
EEF1E1	5978.5
RPL22	5939.0
MRPL45	5839.0
MRPS2	5800.0
RPS14	5784.0
RPL31	5673.0
MRPL50	5621.0
SRP72	5465.0
SSR4	5408.0
MRPL40	5368.0
RPN2	5298.0
RPS26	5195.0
EIF2S1	5177.0
MRPL22	5146.0
MTIF3	5074.0
MRPL46	4943.0
GSPT1	4905.0
RPL9	4882.0
CARS1	4806.0
RPS3A	4794.0
EEF1A1	4762.0
MRPL20	4603.0
MRPL47	4579.0
MRPS33	4506.0
RPL19	4494.0
MRPL12	4269.0
MRPS9	4258.0
MARS1	4257.0
RPL5	4255.0
RPS21	4017.0
DARS1	3988.0
GADD45GIP1	3958.0
MRPS6	3955.0
MRPL44	3931.0
MRPL3	3905.0
EEF1B2	3903.0
SSR3	3879.0
EIF2S2	3845.0
MRPL11	3798.0
MRPL13	3789.0
RPS13	3688.0
MRPL35	3604.0
EIF5	3580.0
EIF1AX	3548.0
MRPL32	3475.0
RPS8	3383.0
MRPL18	3358.0
MRPL10	3267.0
MRPL33	3221.0
MRPL43	3190.0
RPS28	3175.0
AIMP2	3169.0
RPL7	3151.0
EIF2B3	3068.0
SEC61B	3048.0
RARS2	3043.0
SRP19	2991.0
RPL27	2912.0
RPL18	2790.0
LARS2	2718.0
EIF2B2	2716.0
RPS3	2715.0
GSPT2	2691.0
MRPL52	2647.0
MRPS18C	2564.0
RPS4X	2555.0
MRPS16	2548.0
MRPL19	2510.0
RPS11	2321.0
EIF3J	2169.0
EIF4A1	2154.0
DDOST	2136.0
MRPL27	2126.0
RPS19	2111.0
RPL37A	2071.0
FARSA	1906.0
SEC11A	1883.0
MRPS23	1674.0
APEH	1541.0
SPCS2	1359.0
RPL36	1297.0
EIF3C	1287.5
EIF3B	1269.0
MTIF2	1252.0
MRPL21	1230.0
MRPL15	1187.0
YARS1	1102.0
FARS2	980.0
SPCS3	834.0
GFM2	816.0
LARS1	795.0
MRPL55	741.0
RPL10A	667.0
KARS1	648.0
MRPL53	586.0
MRPL49	582.0
SRPRA	471.0
MRPL54	450.0
MRPL39	395.0
MRPS31	362.0
RPL11	231.0
RPL21	231.0
EIF2S3	137.5
MRPS30	45.0
EIF4E	41.0
ETF1	-32.0
MRPS34	-44.0
MRPS5	-53.0
TUFM	-107.0
MRPS7	-161.0
SRP54	-175.0
SEC11C	-221.0
RPS25	-242.0
MRPS15	-371.0
EIF2B4	-372.0
RARS1	-424.0
MRPS12	-431.0
EEF1G	-647.0
RPLP1	-660.0
MRPS11	-799.0
EIF3M	-835.0
SRPRB	-853.0
EEF1A2	-854.0
MRPS26	-888.0
YARS2	-1090.0
MRPL48	-1212.0
MRPS22	-1452.0
MRPL9	-1492.0
RPSA	-1493.0
FARSB	-1497.0
RPS2	-1703.0
MRPS18A	-1837.0
RPS17	-1958.0
RPS10	-1984.5
RPL23	-2023.0
RPL18A	-2151.0
RPS7	-2157.0
UBA52	-2166.0
MRPL16	-2312.0
RPN1	-2344.0
EIF4H	-2444.0
MRPS10	-2682.0
MRPS27	-2810.0
SEC61G	-2848.0
EEF1D	-2901.0
MRPL58	-3023.0
RPS27L	-3093.0
RPL35	-3206.0
IARS2	-3217.0
RPL24	-3268.0
MRPS25	-3279.0
RPL28	-3293.0
EIF3L	-3353.0
EIF3F	-3615.0
MTFMT	-3773.0
EIF5B	-3801.0
MRPL28	-3922.0
SPCS1	-3937.0
EIF3D	-4062.0
SRP68	-4122.0
MRPL38	-4142.0
RPL8	-4167.0
OXA1L	-4251.0
EEF2	-4255.0
MRPL34	-4385.0
MRPL41	-4451.0
MRPL30	-4489.5
TRMT112	-4639.0
EIF3A	-4675.0
MRPL4	-4800.0
DARS2	-4831.0
N6AMT1	-4864.0
MRRF	-4989.0
TSFM	-5028.0
VARS1	-5052.0
AARS1	-5067.0
EIF3G	-5370.0
SEC61A2	-5387.0
EIF3H	-5607.0
SARS1	-5612.0
GFM1	-5626.0
RPL38	-5629.0
ERAL1	-5635.0
SRP14	-5681.0
EIF2B5	-5686.0
RPS6	-5720.0
SARS2	-5926.5
MRPS21	-6064.0
RPL15	-6128.0
TARS2	-6151.0
MTRF1L	-6305.0
MRPS36	-6427.0
AARS2	-6494.0
EIF4EBP1	-6644.0
RPL23A	-6843.0
MRPL51	-6884.0
WARS2	-7035.0
RPL3L	-7058.0
RPL13	-7209.0
MRPL37	-7284.0
VARS2	-7367.0
SSR1	-7497.0
RPS9	-7535.0
MRPS17	-7874.5
EIF3K	-8130.0
CARS2	-8624.0
FAU	-8625.0
EIF4G1	-8658.0
RPL35A	-8900.0

---

Interferon alpha/beta signaling

Interferon alpha/beta signaling

	586
set	Interferon alpha/beta signaling
setSize	63
pANOVA	7.04e-05
s.dist	-0.29
p.adjustANOVA	0.0107

Top enriched genes

Top 20 genes

GeneID	Gene Rank
OAS1	-9078.0
IP6K2	-8814.0
IRF5	-8770.0
OAS3	-8197.0
HLA-A	-8118.5
HLA-B	-8118.5
HLA-C	-8118.5
HLA-E	-8118.5
HLA-F	-8118.5
HLA-G	-8118.5
MX1	-7569.0
IFNAR1	-7388.0
IFIT3	-7329.0
RSAD2	-7050.0
USP18	-6844.5
STAT2	-6464.0
IRF6	-5882.0
IFITM1	-5649.0
IFITM2	-5649.0
IFITM3	-5649.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
OAS1	-9078.0
IP6K2	-8814.0
IRF5	-8770.0
OAS3	-8197.0
HLA-A	-8118.5
HLA-B	-8118.5
HLA-C	-8118.5
HLA-E	-8118.5
HLA-F	-8118.5
HLA-G	-8118.5
MX1	-7569.0
IFNAR1	-7388.0
IFIT3	-7329.0
RSAD2	-7050.0
USP18	-6844.5
STAT2	-6464.0
IRF6	-5882.0
IFITM1	-5649.0
IFITM2	-5649.0
IFITM3	-5649.0
JAK1	-5621.0
IFNA1	-5355.0
IFNA10	-5355.0
IFNA14	-5355.0
IFNA16	-5355.0
IFNA17	-5355.0
IFNA2	-5355.0
IFNA21	-5355.0
IFNA4	-5355.0
IFNA5	-5355.0
IFNA6	-5355.0
IFNA7	-5355.0
IFNA8	-5355.0
ISG20	-5075.0
IRF1	-4752.0
IRF7	-4727.0
BST2	-4688.0
IRF9	-4680.0
ADAR	-4323.0
GBP2	-3613.0
IRF3	-3543.0
IFIT2	-3196.0
IFNAR2	-3030.0
TYK2	-2663.0
IRF8	-2275.0
OASL	-2132.0
ISG15	1321.0
EGR1	3598.0
PTPN11	3701.0
IFI35	3793.0
SOCS3	3999.0
PTPN6	4670.0
ABCE1	4834.0
IRF2	5903.0
IRF4	6589.0
PTPN1	6830.0
SOCS1	6890.0
OAS2	7501.0
XAF1	7601.0
RNASEL	7612.0
PSMB8	7643.0
STAT1	8658.0
SAMHD1	8677.0

---

Biological oxidations

Biological oxidations

	119
set	Biological oxidations
setSize	176
pANOVA	7.41e-05
s.dist	-0.173
p.adjustANOVA	0.0107

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UGT1A1	-9062.0
CES2	-9059.0
CYP2A13	-9057.0
CYP2A6	-9057.0
CYP2A7	-9057.0
SULT2A1	-9051.0
GSTM2	-9046.0
CYP4F8	-9040.0
CYP2D6	-9035.5
CYP2E1	-8999.0
CYP3A4	-8991.0
CYP3A43	-8991.0
CYP3A5	-8991.0
CYP3A7	-8991.0
ARNT	-8977.0
SULT1C2	-8909.0
CYB5B	-8813.0
MAT1A	-8783.0
GSTA5	-8728.0
CES1	-8705.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UGT1A1	-9062.0
CES2	-9059.0
CYP2A13	-9057.0
CYP2A6	-9057.0
CYP2A7	-9057.0
SULT2A1	-9051.0
GSTM2	-9046.0
CYP4F8	-9040.0
CYP2D6	-9035.5
CYP2E1	-8999.0
CYP3A4	-8991.0
CYP3A43	-8991.0
CYP3A5	-8991.0
CYP3A7	-8991.0
ARNT	-8977.0
SULT1C2	-8909.0
CYB5B	-8813.0
MAT1A	-8783.0
GSTA5	-8728.0
CES1	-8705.0
GSTZ1	-8695.0
AHRR	-8688.0
GSTT2	-8637.5
GSTT2B	-8637.5
UGT2A3	-8632.0
CYP2F1	-8491.0
SULT1E1	-8483.5
DPEP1	-8348.0
CYP46A1	-8248.0
MGST1	-8188.0
CYP4F2	-8108.0
GSTM1	-8025.0
GGT6	-7974.0
CYP2C18	-7923.5
ALDH2	-7822.5
CYP4A11	-7728.5
CYP4A22	-7728.5
CYP4F11	-7728.5
CYP4F12	-7728.5
SLC35B3	-7717.0
AKR7L	-7680.0
ACSS1	-7584.0
MTRR	-7315.0
FMO2	-7251.0
AKR7A3	-7174.0
GSTP1	-7158.0
ABHD14B	-7139.0
CMBL	-7011.0
FMO3	-6965.0
CYP1A2	-6798.0
NCOA1	-6733.0
CYP4B1	-6651.0
ACSM5	-6562.0
COMT	-6362.0
MAOA	-6052.0
ACSM4	-6045.0
AIP	-5975.0
POR	-5945.0
GGT5	-5861.0
CYP26B1	-5722.0
SMOX	-5524.0
RXRA	-5221.0
NCOA2	-5184.0
CYB5R3	-5151.0
GSTM3	-5144.0
MTR	-5111.0
DPEP2	-4879.0
N6AMT1	-4864.0
SLC26A1	-4701.0
ALDH1B1	-4681.0
TRMT112	-4639.0
CYP24A1	-4478.0
CYP4F3	-4081.0
CYP2W1	-3941.0
SLC26A2	-3919.0
ALDH1A1	-3766.0
CYP27B1	-3689.0
AHCY	-3314.0
GGT7	-3254.0
PODXL2	-3241.0
MAOB	-3229.0
GSTK1	-3187.0
CHAC1	-3179.0
HSP90AB1	-3151.0
EPHX1	-2961.0
SLC35D1	-2880.0
CYP4V2	-2726.0
ADH7	-2536.0
ESD	-2500.0
SULT1A3	-2333.5
SULT1A4	-2333.5
ACSS2	-2133.0
AS3MT	-1670.0
PAOX	-1652.5
CYP2S1	-1638.0
CBR3	-1562.5
GSS	-1324.0
CYP2R1	-1234.0
AKR1A1	-841.0
GSTO2	-624.0
UGT3A2	-338.5
CYP2J2	-235.0
GGCT	-62.5
BPNT1	105.0
ACY1	106.5
CYP1A1	359.0
AADAC	480.0
GGT1	592.0
SULT1A1	746.0
SULT1A2	746.0
AOC3	784.0
GCLC	786.0
CYP51A1	1117.0
SULT6B1	1206.0
CYP27A1	1302.0
CYP8B1	1456.0
AOC1	1466.0
ARNT2	1509.0
CYP19A1	1797.0
CYP21A2	2301.0
MGST2	2307.0
CYP2U1	2375.0
HPGDS	2411.0
TPST2	2499.0
ADH5	2725.0
AHR	2943.5
CYP7A1	3065.0
ACY3	3112.0
POMC	3261.0
GSTM4	3592.0
NAT1	3626.5
NAT2	3626.5
CYP4F22	4080.0
SULT1B1	4254.0
MTARC2	4279.0
PAPSS1	4326.0
PTGES3	4369.0
FDX2	4488.5
FDX1	4538.0
NR1H4	4600.0
SULT4A1	4631.0
MGST3	4742.0
BPHL	4818.0
ALDH3A1	4826.0
PTGS1	4865.0
CYP7B1	4950.0
MTARC1	5152.5
PAPSS2	5409.0
FMO1	5603.0
SLC35B2	5607.0
TBXAS1	5711.0
CYP26A1	5725.0
CNDP2	6042.0
CYP39A1	6053.0
UGP2	6062.0
UGDH	6178.0
CYP11A1	6250.0
CHAC2	6274.0
NQO2	6527.0
ACSM1	6711.0
GLYAT	6865.0
MAT2A	6915.0
GCLM	6937.0
DPEP3	7176.0
OPLAH	7290.0
CYP26C1	7324.0
NNMT	7566.0
TPMT	8205.0
MAT2B	8229.0
GSTO1	8455.0
SULT2B1	8608.0
CYP1B1	8673.0
BPNT2	8715.0
TPST1	8787.0
ABHD10	8844.0
PTGIS	8898.0

---

Assembly of active LPL and LIPC lipase complexes

Assembly of active LPL and LIPC lipase complexes

	96
set	Assembly of active LPL and LIPC lipase complexes
setSize	19
pANOVA	0.000116
s.dist	-0.511
p.adjustANOVA	0.0152

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CIDEC	-8897.0
MBTPS2	-8761.0
APOA5	-8466.0
MBTPS1	-7804.0
APOC2	-7531.5
CREB3L3	-7263.0
APOA4	-6758.0
ANGPTL3	-6400.0
FURIN	-6399.0
ANGPTL4	-6243.0
LIPC	-5932.0
LMF2	-5317.0
FGF21	-5116.0
ANGPTL8	-4094.0
GPIHBP1	-3404.0
LPL	-2467.0
PCSK5	3308.0
PCSK6	4262.0
LMF1	4677.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CIDEC	-8897.0
MBTPS2	-8761.0
APOA5	-8466.0
MBTPS1	-7804.0
APOC2	-7531.5
CREB3L3	-7263.0
APOA4	-6758.0
ANGPTL3	-6400.0
FURIN	-6399.0
ANGPTL4	-6243.0
LIPC	-5932.0
LMF2	-5317.0
FGF21	-5116.0
ANGPTL8	-4094.0
GPIHBP1	-3404.0
LPL	-2467.0
PCSK5	3308.0
PCSK6	4262.0
LMF1	4677.0

---

Cell death signalling via NRAGE, NRIF and NADE

Cell death signalling via NRAGE, NRIF and NADE

	169
set	Cell death signalling via NRAGE, NRIF and NADE
setSize	72
pANOVA	0.000242
s.dist	-0.25
p.adjustANOVA	0.0292

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ARHGEF37	-8834
ARHGEF1	-8718
OBSCN	-8574
ARHGEF7	-8534
PLEKHG5	-8454
ITSN1	-8377
MAGED1	-8312
ARHGEF11	-8287
NCSTN	-8213
NGFR	-8192
ARHGEF40	-7699
MCF2	-7686
ARHGEF16	-7667
ABR	-7655
MCF2L	-7517
ARHGEF5	-7293
PLEKHG2	-7206
VAV3	-7088
ARHGEF17	-6885
ARHGEF10L	-6624

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ARHGEF37	-8834.0
ARHGEF1	-8718.0
OBSCN	-8574.0
ARHGEF7	-8534.0
PLEKHG5	-8454.0
ITSN1	-8377.0
MAGED1	-8312.0
ARHGEF11	-8287.0
NCSTN	-8213.0
NGFR	-8192.0
ARHGEF40	-7699.0
MCF2	-7686.0
ARHGEF16	-7667.0
ABR	-7655.0
MCF2L	-7517.0
ARHGEF5	-7293.0
PLEKHG2	-7206.0
VAV3	-7088.0
ARHGEF17	-6885.0
ARHGEF10L	-6624.0
UBC	-6432.0
APH1B	-6387.0
TRIO	-6348.0
BCL2L11	-6346.0
FGD4	-6196.0
FGD1	-5982.0
YWHAE	-5754.0
ARHGEF19	-5545.0
SQSTM1	-5320.0
ARHGEF6	-5311.0
CASP2	-5200.0
AKAP13	-5190.0
NET1	-4984.0
NGEF	-4851.0
ARHGEF38	-4562.0
CASP3	-4363.0
BEX3	-3892.0
PSEN1	-3548.0
PREX1	-3045.0
SOS1	-2808.0
ARHGEF18	-2547.5
TRAF6	-2185.0
AATF	-2176.0
PSEN2	-2171.5
UBA52	-2166.0
PSENEN	-1907.0
ARHGEF39	-1272.0
ARHGEF10	-775.0
ARHGEF15	-470.0
ARHGEF33	-451.0
KALRN	-177.0
BAD	928.0
APH1A	1110.0
VAV1	1912.0
RAC1	2240.0
NGF	2470.0
FGD2	4170.0
ITGB3BP	4443.0
TIAM2	4841.0
RASGRF2	5220.0
GNA13	5282.0
VAV2	5813.0
MAPK8	5956.0
ARHGEF12	6104.0
FGD3	6255.0
TIAM1	6942.0
ECT2	7350.0
RPS27A	7369.0
ARHGEF3	7632.0
SOS2	7658.0
ARHGEF2	7980.0
ARHGEF26	8302.0

---

Cell junction organization

Cell junction organization

	170
set	Cell junction organization
setSize	85
pANOVA	0.000301
s.dist	-0.227
p.adjustANOVA	0.0314

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PLEC	-9079.0
PXN	-9019.0
CLDN10	-8984.0
CLDN2	-8877.0
SDK2	-8789.0
FERMT2	-8675.0
CDH4	-8642.0
PARVB	-8581.0
NECTIN2	-8501.0
FBLIM1	-8331.0
JUP	-8056.0
CDH5	-8036.0
FLNC	-8034.0
CLDN7	-7969.5
CLDN14	-7884.0
PARD3	-7779.0
VASP	-7621.0
ANG	-7566.0
CDH13	-7131.0
CLDN9	-7005.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PLEC	-9079.0
PXN	-9019.0
CLDN10	-8984.0
CLDN2	-8877.0
SDK2	-8789.0
FERMT2	-8675.0
CDH4	-8642.0
PARVB	-8581.0
NECTIN2	-8501.0
FBLIM1	-8331.0
JUP	-8056.0
CDH5	-8036.0
FLNC	-8034.0
CLDN7	-7969.5
CLDN14	-7884.0
PARD3	-7779.0
VASP	-7621.0
ANG	-7566.0
CDH13	-7131.0
CLDN9	-7005.0
ITGB4	-6853.0
CDH9	-6602.0
TESK1	-6401.0
PATJ	-6367.0
PARD6G	-6344.0
CLDN1	-6211.0
LAMA3	-6177.0
CLDN4	-6023.0
CTNND1	-6002.0
LIMS1	-5950.0
ITGA6	-5895.0
NECTIN1	-5893.0
CLDN3	-5590.0
PARD6B	-5450.0
ARHGEF6	-5311.0
CRB3	-5128.0
CLDN23	-5078.0
CDH15	-4795.0
CDH17	-4741.0
CTNNA1	-4715.0
CDH1	-4511.0
CDH12	-4207.0
F11R	-3912.0
LIMS2	-3484.0
CDH10	-3034.0
AFDN	-2352.0
CLDN19	-2269.0
CLDN8	-2194.0
PRKCI	-2165.0
NECTIN4	-2014.0
CLDN16	-1562.5
CDH8	-850.0
CLDN18	-282.0
CADM2	70.0
CLDN11	725.0
CDH3	1031.0
ACTN1	1114.0
CD151	1741.0
CTNNB1	1809.0
ILK	1817.0
PVR	2238.0
CDH24	2287.0
CDH18	2439.0
ITGB1	2469.0
RSU1	2530.0
FLNA	2688.0
PARVA	3142.0
CLDN20	3374.0
CLDN15	3865.0
MPP5	3925.0
CDH11	4613.0
CLDN5	4896.0
CDH6	5171.0
CDH2	5589.0
DST	5910.0
CLDN12	5952.0
CLDN6	6032.0
PARD6A	6114.0
CDH7	6360.0
LAMB3	6421.0
NECTIN3	6461.0
CADM3	7556.0
CADM1	8716.0
COL17A1	8726.0
LAMC2	8913.0

---

Sulfur amino acid metabolism

Sulfur amino acid metabolism

	1231
set	Sulfur amino acid metabolism
setSize	25
pANOVA	0.000303
s.dist	-0.417
p.adjustANOVA	0.0314

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MAT1A	-8783.0
CDO1	-8662.0
CBS	-8643.5
CBSL	-8643.5
CSAD	-8554.0
BHMT	-8229.0
APIP	-8053.0
BHMT2	-8052.0
MTRR	-7315.0
MPST	-6695.0
MRI1	-5775.0
CTH	-5465.0
MTR	-5111.0
TST	-3834.0
SUOX	-3648.0
AHCY	-3314.0
ADI1	-3222.0
TXN2	-1312.0
ENOPH1	-504.0
SLC25A10	1159.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MAT1A	-8783.0
CDO1	-8662.0
CBS	-8643.5
CBSL	-8643.5
CSAD	-8554.0
BHMT	-8229.0
APIP	-8053.0
BHMT2	-8052.0
MTRR	-7315.0
MPST	-6695.0
MRI1	-5775.0
CTH	-5465.0
MTR	-5111.0
TST	-3834.0
SUOX	-3648.0
AHCY	-3314.0
ADI1	-3222.0
TXN2	-1312.0
ENOPH1	-504.0
SLC25A10	1159.5
GOT2	2252.0
TSTD1	2351.0
ETHE1	2775.0
MTAP	4294.5
GOT1	5480.0

---

Phenylalanine and tyrosine metabolism

Phenylalanine and tyrosine metabolism

	872
set	Phenylalanine and tyrosine metabolism
setSize	11
pANOVA	0.000355
s.dist	-0.622
p.adjustANOVA	0.0336

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IL4I1	-8943.0
GSTZ1	-8695.0
PAH	-8599.0
HPD	-8142.0
HGD	-7311.0
FAH	-6438.0
QDPR	-5654.0
PCBD1	-5138.0
ASRGL1	-4963.0
TAT	-1127.0
KYAT1	2675.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IL4I1	-8943.0
GSTZ1	-8695.0
PAH	-8599.0
HPD	-8142.0
HGD	-7311.0
FAH	-6438.0
QDPR	-5654.0
PCBD1	-5138.0
ASRGL1	-4963.0
TAT	-1127.0
KYAT1	2675.5

---

Extracellular matrix organization

Extracellular matrix organization

	382
set	Extracellular matrix organization
setSize	274
pANOVA	0.000372
s.dist	0.125
p.adjustANOVA	0.0336

Top enriched genes

Top 20 genes

GeneID	Gene Rank
COL1A2	8941
LOX	8924
LAMC2	8913
COMP	8906
DDR1	8892
TGFB2	8828
VCAM1	8798
EFEMP2	8730
COL17A1	8726
THBS1	8627
COL11A2	8584
NRXN1	8487
COL13A1	8432
GDF5	8430
P4HA3	8415
LAMA2	8370
COL16A1	8364
LOXL2	8342
PCOLCE	8334
NCAN	8319

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
COL1A2	8941.0
LOX	8924.0
LAMC2	8913.0
COMP	8906.0
DDR1	8892.0
TGFB2	8828.0
VCAM1	8798.0
EFEMP2	8730.0
COL17A1	8726.0
THBS1	8627.0
COL11A2	8584.0
NRXN1	8487.0
COL13A1	8432.0
GDF5	8430.0
P4HA3	8415.0
LAMA2	8370.0
COL16A1	8364.0
LOXL2	8342.0
PCOLCE	8334.0
NCAN	8319.0
P4HA2	8315.0
SERPINH1	8239.0
ASPN	8232.0
HTRA1	8144.0
TRAPPC4	8123.0
ADAMTS2	8086.0
COL8A2	8066.0
ITGA2	8050.0
COL1A1	7952.0
CAST	7947.0
CD47	7939.0
COL9A1	7923.0
IBSP	7884.0
PHYKPL	7845.0
VCAN	7807.0
DCN	7802.0
FMOD	7779.0
ITGA9	7572.0
MMP3	7551.0
MMP2	7540.0
MMP9	7518.0
TNC	7516.0
MATN4	7494.0
COL12A1	7478.0
DMD	7463.0
MFAP5	7417.0
ADAMTS3	7408.0
OPTC	7380.0
SDC1	7316.0
BMP1	7235.0
COL5A1	7233.0
MMP16	7188.0
COL8A1	7168.0
COL2A1	7114.0
LOXL1	7085.0
FBLN5	7064.0
ACAN	7037.0
PCOLCE2	6917.0
FN1	6913.0
PPIB	6887.0
CTSK	6859.0
COL11A1	6757.0
TIMP2	6680.0
LTBP1	6514.0
CASK	6499.0
SDC2	6449.0
BSG	6428.0
LAMB3	6421.0
CMA1	6414.0
ADAM9	6383.0
CAPN8	6351.0
BMP2	6309.0
CD44	6282.0
ADAMTS8	6254.0
TLL2	6245.0
LTBP2	6149.0
DDR2	6135.0
SPARC	6116.0
ITGA11	6092.0
LOXL4	6012.0
TNN	5931.0
P3H2	5928.0
DST	5910.0
FBN1	5838.0
BGN	5787.0
HAPLN1	5604.0
P4HA1	5544.0
COL14A1	5203.0
MFAP2	5009.0
FBN2	5007.0
ADAM19	4993.0
CAPN6	4958.0
MFAP4	4885.0
ADAMTS14	4789.0
COL6A2	4759.0
LAMA1	4727.0
PLOD3	4609.0
NTN4	4587.0
ICAM4	4394.0
MATN3	4328.0
BMP4	4187.0
ITGA7	4112.0
TLL1	4083.0
MMP20	3915.0
COL3A1	3907.0
P3H3	3882.0
ICAM5	3799.0
COL26A1	3774.0
ADAMTS9	3756.0
COL6A1	3749.0
ADAMTS5	3692.0
COL4A6	3630.0
ADAMTS16	3486.0
CTRB1	3316.5
CTRB2	3316.5
COL23A1	3188.0
ADAMTS1	3176.0
COL5A2	3064.0
ICAM1	3053.0
MMP14	2974.0
CRTAP	2918.0
FGF2	2815.0
BMP7	2742.0
MMP7	2736.0
PTPRS	2729.0
CTSD	2669.5
ITGB1	2469.0
CTSS	2396.0
ITGA10	2327.0
ITGAV	2243.0
MADCAM1	2232.0
P3H1	2050.0
MMP1	2049.0
CD151	1741.0
ELN	1616.0
ADAMTS18	1599.0
KLK2	1449.5
CAPN1	1166.0
ACTN1	1114.0
ADAM12	1062.0
COL27A1	951.0
LUM	941.0
CAPN9	896.0
CAPN11	818.0
TGFB3	801.0
MMP17	768.0
FBLN2	754.0
PLOD1	638.0
LTBP3	636.0
NID1	625.0
DSPP	575.0
COL19A1	452.0
COL4A3	385.0
CTSG	231.0
LAMB1	139.0
CAPN7	118.0
BMP10	36.0
CAPN13	4.0
PRSS1	-190.0
PRSS2	-190.0
MMP12	-309.0
ITGB2	-462.0
ELANE	-671.0
MMP13	-756.0
LRP4	-808.0
COL5A3	-869.0
COLGALT1	-898.0
MATN1	-987.0
AGRN	-1136.0
KLK7	-1148.0
TGFB1	-1162.0
DMP1	-1207.0
TIMP1	-1254.0
CTSB	-1337.0
ITGB8	-1484.0
MMP19	-1645.0
FBLN1	-1728.0
ITGAL	-1761.0
PRKCA	-1808.0
CAPN15	-1858.0
JAM2	-1946.0
SCUBE1	-1981.0
SDC3	-2040.0
LOXL3	-2045.0
ADAM17	-2112.0
LAMA4	-2168.0
ITGA8	-2280.0
P4HB	-2423.0
ADAM8	-2497.0
EFEMP1	-2671.0
ICAM2	-2737.0
LTBP4	-2926.0
SDC4	-2987.0
COL28A1	-2995.0
COL4A5	-3059.0
ITGA1	-3067.0
JAM3	-3140.0
CAPN5	-3167.0
CAPN2	-3290.0
SERPINE1	-3327.0
ITGB3	-3380.5
LAMC1	-3476.0
PSEN1	-3548.0
HSPG2	-3764.0
COL6A6	-3769.0
A2M	-3884.0
F11R	-3912.0
SCUBE3	-4132.0
CAPN10	-4166.0
ITGB6	-4238.0
ITGA4	-4297.0
CASP3	-4363.0
CEACAM1	-4406.5
CEACAM6	-4406.5
CEACAM8	-4406.5
COL4A1	-4472.0
CAPN12	-4477.0
CDH1	-4511.0
CTSV	-4546.0
COL4A2	-4819.0
PDGFB	-4881.0
MMP24	-4965.0
SPOCK3	-5006.0
ADAMTS4	-5074.0
MFAP3	-5088.0
COL18A1	-5131.0
LAMC3	-5168.0
LAMA5	-5206.0
ITGAX	-5237.0
ITGAE	-5312.0
ADAM10	-5402.0
KDR	-5733.0
COL6A5	-5779.0
MUSK	-5811.0
ITGA6	-5895.0
KLKB1	-6048.0
COL15A1	-6154.0
LAMA3	-6177.0
MMP15	-6347.0
FURIN	-6399.0
ITGA3	-6852.0
ITGB4	-6853.0
ADAM15	-6936.0
TMPRSS6	-6939.0
MMP11	-7212.0
ITGA2B	-7222.0
PDGFA	-7301.0
TNR	-7305.0
CAPNS1	-7620.0
SPP1	-7652.0
PXDN	-7676.0
LAMB2	-7709.0
COL9A2	-7743.0
ITGA5	-7756.0
BCAN	-7782.0
COLGALT2	-7793.0
MMP8	-7832.0
ITGB7	-7863.0
PLOD2	-7959.0
DAG1	-7964.0
FGG	-8035.0
NCSTN	-8213.0
NID2	-8273.0
COL25A1	-8293.0
CAPN3	-8435.0
FGA	-8696.0
TTR	-8839.0
VTN	-8869.5
NCAM1	-8937.0
SH3PXD2A	-8986.0
PLG	-9005.0
ITGAM	-9020.0
FGB	-9053.0
PLEC	-9079.0

---

Cytochrome P450 - arranged by substrate type

Cytochrome P450 - arranged by substrate type

	239
set	Cytochrome P450 - arranged by substrate type
setSize	58
pANOVA	0.000424
s.dist	-0.268
p.adjustANOVA	0.0361

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CYP2A13	-9057.0
CYP2A6	-9057.0
CYP2A7	-9057.0
CYP4F8	-9040.0
CYP2D6	-9035.5
CYP2E1	-8999.0
CYP3A4	-8991.0
CYP3A43	-8991.0
CYP3A5	-8991.0
CYP3A7	-8991.0
ARNT	-8977.0
AHRR	-8688.0
CYP2F1	-8491.0
CYP46A1	-8248.0
CYP4F2	-8108.0
CYP2C18	-7923.5
CYP4A11	-7728.5
CYP4A22	-7728.5
CYP4F11	-7728.5
CYP4F12	-7728.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CYP2A13	-9057.0
CYP2A6	-9057.0
CYP2A7	-9057.0
CYP4F8	-9040.0
CYP2D6	-9035.5
CYP2E1	-8999.0
CYP3A4	-8991.0
CYP3A43	-8991.0
CYP3A5	-8991.0
CYP3A7	-8991.0
ARNT	-8977.0
AHRR	-8688.0
CYP2F1	-8491.0
CYP46A1	-8248.0
CYP4F2	-8108.0
CYP2C18	-7923.5
CYP4A11	-7728.5
CYP4A22	-7728.5
CYP4F11	-7728.5
CYP4F12	-7728.5
CYP1A2	-6798.0
NCOA1	-6733.0
CYP4B1	-6651.0
POR	-5945.0
CYP26B1	-5722.0
RXRA	-5221.0
NCOA2	-5184.0
CYP24A1	-4478.0
CYP4F3	-4081.0
CYP2W1	-3941.0
CYP27B1	-3689.0
CYP4V2	-2726.0
CYP2S1	-1638.0
CYP2R1	-1234.0
CYP2J2	-235.0
CYP1A1	359.0
CYP51A1	1117.0
CYP27A1	1302.0
CYP8B1	1456.0
ARNT2	1509.0
CYP19A1	1797.0
CYP21A2	2301.0
CYP2U1	2375.0
AHR	2943.5
CYP7A1	3065.0
POMC	3261.0
CYP4F22	4080.0
FDX2	4488.5
FDX1	4538.0
NR1H4	4600.0
CYP7B1	4950.0
TBXAS1	5711.0
CYP26A1	5725.0
CYP39A1	6053.0
CYP11A1	6250.0
CYP26C1	7324.0
CYP1B1	8673.0
PTGIS	8898.0

---

p75 NTR receptor-mediated signalling

p75 NTR receptor-mediated signalling

	1433
set	p75 NTR receptor-mediated signalling
setSize	92
pANOVA	0.000471
s.dist	-0.211
p.adjustANOVA	0.0379

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ARHGEF37	-8834
ARHGEF1	-8718
OBSCN	-8574
ARHGEF7	-8534
PLEKHG5	-8454
ITSN1	-8377
MAGED1	-8312
ARHGEF11	-8287
RTN4	-8274
NCSTN	-8213
NGFR	-8192
ARHGEF40	-7699
MCF2	-7686
ARHGEF16	-7667
ABR	-7655
MCF2L	-7517
ARHGEF5	-7293
PLEKHG2	-7206
VAV3	-7088
ARHGEF17	-6885

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ARHGEF37	-8834.0
ARHGEF1	-8718.0
OBSCN	-8574.0
ARHGEF7	-8534.0
PLEKHG5	-8454.0
ITSN1	-8377.0
MAGED1	-8312.0
ARHGEF11	-8287.0
RTN4	-8274.0
NCSTN	-8213.0
NGFR	-8192.0
ARHGEF40	-7699.0
MCF2	-7686.0
ARHGEF16	-7667.0
ABR	-7655.0
MCF2L	-7517.0
ARHGEF5	-7293.0
PLEKHG2	-7206.0
VAV3	-7088.0
ARHGEF17	-6885.0
ARHGEF10L	-6624.0
UBC	-6432.0
APH1B	-6387.0
TRIO	-6348.0
BCL2L11	-6346.0
FGD4	-6196.0
FGD1	-5982.0
MAG	-5858.0
YWHAE	-5754.0
ARHGEF19	-5545.0
SQSTM1	-5320.0
ARHGEF6	-5311.0
CASP2	-5200.0
AKAP13	-5190.0
NET1	-4984.0
NGEF	-4851.0
ARHGEF38	-4562.0
CASP3	-4363.0
RIPK2	-4098.0
BEX3	-3892.0
PRDM4	-3727.0
PSEN1	-3548.0
MYD88	-3411.0
PREX1	-3045.0
SOS1	-2808.0
ARHGDIA	-2696.0
NFKB1	-2579.0
ARHGEF18	-2547.5
LINGO1	-2353.0
TRAF6	-2185.0
AATF	-2176.0
PSEN2	-2171.5
UBA52	-2166.0
PRKCI	-2165.0
ADAM17	-2112.0
RELA	-2108.0
PSENEN	-1907.0
OMG	-1376.0
ARHGEF39	-1272.0
ARHGEF10	-775.0
RHOA	-640.0
ARHGEF15	-470.0
ARHGEF33	-451.0
KALRN	-177.0
IRAK1	791.0
BAD	928.0
SORCS3	985.0
APH1A	1110.0
VAV1	1912.0
RAC1	2240.0
NGF	2470.0
HDAC2	3553.0
IKBKB	4039.0
FGD2	4170.0
ITGB3BP	4443.0
TIAM2	4841.0
RASGRF2	5220.0
GNA13	5282.0
HDAC3	5550.0
SMPD2	5759.0
VAV2	5813.0
MAPK8	5956.0
ARHGEF12	6104.0
FGD3	6255.0
TIAM1	6942.0
HDAC1	7175.0
ECT2	7350.0
RPS27A	7369.0
ARHGEF3	7632.0
SOS2	7658.0
ARHGEF2	7980.0
ARHGEF26	8302.0

---

Plasma lipoprotein assembly, remodeling, and clearance

Plasma lipoprotein assembly, remodeling, and clearance

	882
set	Plasma lipoprotein assembly, remodeling, and clearance
setSize	68
pANOVA	0.000554
s.dist	-0.242
p.adjustANOVA	0.0407

Top enriched genes

Top 20 genes

GeneID	Gene Rank
APOC1	-8963.0
APOC3	-8904.0
CIDEC	-8897.0
ABCG1	-8866.0
SCARB1	-8857.0
APOE	-8836.0
MBTPS2	-8761.0
APOA5	-8466.0
CUBN	-8462.0
LSR	-8207.0
MTTP	-8003.0
MBTPS1	-7804.0
PRKACA	-7713.0
APOC2	-7531.5
APOA2	-7400.0
NR1H3	-7384.0
APOF	-7268.0
CREB3L3	-7263.0
LCAT	-6772.0
APOA4	-6758.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
APOC1	-8963.0
APOC3	-8904.0
CIDEC	-8897.0
ABCG1	-8866.0
SCARB1	-8857.0
APOE	-8836.0
MBTPS2	-8761.0
APOA5	-8466.0
CUBN	-8462.0
LSR	-8207.0
MTTP	-8003.0
MBTPS1	-7804.0
PRKACA	-7713.0
APOC2	-7531.5
APOA2	-7400.0
NR1H3	-7384.0
APOF	-7268.0
CREB3L3	-7263.0
LCAT	-6772.0
APOA4	-6758.0
PRKACB	-6707.0
ANGPTL3	-6400.0
FURIN	-6399.0
ANGPTL4	-6243.0
PCSK9	-6169.0
ABCA1	-6097.0
LIPC	-5932.0
AP2A1	-5700.0
LMF2	-5317.0
LIPG	-5216.0
FGF21	-5116.0
MYLIP	-5032.0
NR1H2	-4967.0
VLDLR	-4329.0
ANGPTL8	-4094.0
A2M	-3884.0
LPA	-3826.0
GPIHBP1	-3404.0
LPL	-2467.0
P4HB	-2423.0
PLTP	-2003.0
APOC4	-1990.0
AMN	-1681.0
AP2S1	-1453.0
APOA1	-547.0
LDLRAP1	515.0
APOB	573.0
SAR1B	1055.0
AP2M1	1347.0
ZDHHC8	2324.0
LDLR	2957.0
PCSK5	3308.0
PCSK6	4262.0
AP2B1	4289.0
CLTC	4525.0
LMF1	4677.0
NPC2	5620.0
AP2A2	6431.0
HDLBP	6636.0
APOBR	6980.0
SOAT1	7007.0
NPC1	7043.0
LIPA	7213.0
BMP1	7235.0
SOAT2	7523.0
ALB	7970.0
NCEH1	8324.0
CLTA	8586.0

---

NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux

NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux

	752
set	NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
setSize	39
pANOVA	0.000562
s.dist	-0.319
p.adjustANOVA	0.0407

Top enriched genes

Top 20 genes

GeneID	Gene Rank
APOC1	-8963.0
ABCG1	-8866.0
APOE	-8836.0
TNRC6B	-8577.0
NCOR2	-8506.0
KDM4A	-8470.5
AGO4	-8424.0
NCOR1	-8129.0
RXRB	-7956.0
APOC2	-7531.5
NR1H3	-7384.0
NCOA1	-6733.0
EEPD1	-6385.0
ABCA1	-6097.0
AGO1	-5804.0
GPS2	-5694.0
TNRC6C	-5527.0
MIR144	-5518.0
AGO2	-5246.0
RXRA	-5221.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
APOC1	-8963.0
ABCG1	-8866.0
APOE	-8836.0
TNRC6B	-8577.0
NCOR2	-8506.0
KDM4A	-8470.5
AGO4	-8424.0
NCOR1	-8129.0
RXRB	-7956.0
APOC2	-7531.5
NR1H3	-7384.0
NCOA1	-6733.0
EEPD1	-6385.0
ABCA1	-6097.0
AGO1	-5804.0
GPS2	-5694.0
TNRC6C	-5527.0
MIR144	-5518.0
AGO2	-5246.0
RXRA	-5221.0
TBL1XR1	-5183.0
NR1H2	-4967.0
APOD	-4213.0
KDM1B	-3115.0
KDM3A	-2751.0
ABCG5	-2445.0
PLTP	-2003.0
APOC4	-1990.0
MIR33A	-1119.0
EP300	1591.0
TBL1X	1601.5
HDAC3	5550.0
MIR26A1	5951.0
MOV10	6056.0
ABCG8	6224.0
MIR26A2	6542.0
AGO3	7448.0
TNRC6A	7675.0
KDM1A	8614.0

---

Signal Transduction

Signal Transduction

	1139
set	Signal Transduction
setSize	2386
pANOVA	0.000712
s.dist	-0.0429
p.adjustANOVA	0.0491

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GABBR1	-9063
C5	-9060
FGB	-9053
RDH16	-9052
KNG1	-9050
TAS1R2	-9042
PAK1	-9034
CRHR2	-9033
STARD8	-9030
MXD4	-9029
PXN	-9019
TLE1	-9016
SAG	-9009
PLIN1	-9007
PLG	-9005
EDNRA	-8998
IGF2	-8965
APOC1	-8963
GFAP	-8957
PDE4D	-8956

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GABBR1	-9063.0
C5	-9060.0
FGB	-9053.0
RDH16	-9052.0
KNG1	-9050.0
TAS1R2	-9042.0
PAK1	-9034.0
CRHR2	-9033.0
STARD8	-9030.0
MXD4	-9029.0
PXN	-9019.0
TLE1	-9016.0
SAG	-9009.0
PLIN1	-9007.0
PLG	-9005.0
EDNRA	-8998.0
IGF2	-8965.0
APOC1	-8963.0
GFAP	-8957.0
PDE4D	-8956.0
MYO9B	-8944.0
SRGAP2	-8939.0
NCAM1	-8937.0
PTGER3	-8925.0
CDKN1A	-8923.0
PDE2A	-8915.0
AKR1B10	-8911.0
APOC3	-8904.0
CAMK2B	-8898.0
CENPP	-8891.0
FOXO4	-8887.0
MEF2A	-8883.0
PRKAR2B	-8880.0
NTRK1	-8876.0
MYH14	-8868.0
ABCG1	-8866.0
PDE11A	-8842.0
TTR	-8839.0
PDGFRB	-8838.0
APOE	-8836.0
ARHGEF37	-8834.0
NDC80	-8832.0
IL2RB	-8825.0
DNM2	-8817.0
ARHGAP17	-8816.0
NRG1	-8815.0
PCK1	-8806.0
PLPPR3	-8805.0
PSME3	-8804.0
CHD8	-8792.0
CSNK2B	-8791.0
HPN	-8779.0
CCL28	-8774.0
RGS17	-8772.0
RRH	-8768.0
WNT4	-8755.0
PDGFC	-8753.0
TAS1R3	-8751.0
DGKE	-8747.0
NR4A1	-8745.0
SGO2	-8734.0
NTSR1	-8726.0
CYFIP1	-8724.0
ARHGEF1	-8718.0
LIMK1	-8717.0
INSR	-8709.0
IKZF1	-8704.0
FGA	-8696.0
ZNF217	-8689.0
P2RY14	-8673.0
ADORA1	-8671.0
NEDD4L	-8665.0
EIF4G1	-8658.0
REST	-8650.0
RPS6KA1	-8610.0
CXCR1	-8608.0
GNAS	-8601.0
FOSB	-8589.0
PBX1	-8578.0
TNRC6B	-8577.0
RGS14	-8576.0
OBSCN	-8574.0
PPP2R5C	-8572.0
PSMD11	-8559.0
OPHN1	-8557.0
GSK3B	-8548.0
ARHGEF7	-8534.0
RARA	-8531.0
RGS5	-8529.0
RGS20	-8516.0
GRK6	-8511.0
NCOR2	-8506.0
PPARG	-8498.0
NUMB	-8494.0
CCL11	-8487.0
GMIP	-8479.0
PPP3CC	-8476.0
CDC37	-8475.0
SPRED3	-8474.0
KDM4A	-8470.5
RGS6	-8457.0
PLEKHG5	-8454.0
CSNK1G2	-8450.0
CDC42	-8440.0
USP2	-8432.0
PDE1B	-8427.0
AGO4	-8424.0
POLR2E	-8423.0
ATP6V0D1	-8410.0
ETV4	-8397.0
PLB1	-8395.0
PSMB10	-8393.0
PLPPR1	-8390.0
ITSN1	-8377.0
PLCB4	-8376.0
LIN7B	-8366.0
RBFOX2	-8362.0
PTK2	-8355.0
CXCR6	-8347.0
MRTFA	-8345.0
TSC2	-8340.0
GRB10	-8326.0
CXCR3	-8323.0
ARAP2	-8318.0
TRH	-8317.0
MAGED1	-8312.0
CHRM3	-8311.0
ATF1	-8305.0
HNRNPH1	-8301.0
SH2D2A	-8300.0
STAT6	-8298.0
CHN2	-8291.5
ARHGEF11	-8287.0
RTN4	-8274.0
USP4	-8272.0
WASF2	-8271.0
VIPR1	-8263.0
IFT88	-8255.0
RNF41	-8243.0
AMOT	-8241.0
MADD	-8225.0
NCSTN	-8213.0
GALR2	-8209.0
BAIAP2	-8193.0
NGFR	-8192.0
DEPDC7	-8183.0
RBP4	-8178.0
KMT2D	-8177.0
DGKZ	-8155.0
TEC	-8139.0
GPSM3	-8134.0
MYC	-8133.0
NCOR1	-8129.0
NUP43	-8128.0
PRKAR2A	-8106.0
EVL	-8105.0
TCF12	-8098.0
PIK3AP1	-8096.0
SRC	-8095.0
TAX1BP3	-8093.0
CHD4	-8089.5
VIP	-8083.0
ACVR1C	-8082.0
CDK1	-8079.0
WIPF2	-8075.0
GLP2R	-8069.0
UBE2D3	-8068.0
JUP	-8056.0
NPY	-8050.0
LPAR5	-8048.0
ATP6V0A2	-8039.0
CDH5	-8036.0
FGG	-8035.0
H2BC1	-8026.0
NUP85	-8017.0
HDAC5	-8016.0
NPY1R	-8014.0
ARHGAP20	-8012.0
NR3C1	-8004.0
XK	-7994.0
PDE4C	-7992.5
ADRB3	-7987.5
STAT5B	-7980.0
QRFPR	-7977.0
PLCB3	-7957.0
RXRB	-7956.0
ASH2L	-7949.0
LEPR	-7925.0
NEDD4	-7922.0
ARC	-7921.0
ARHGAP6	-7915.0
DUSP10	-7908.0
RUVBL1	-7902.0
CCNT1	-7896.0
NPFFR1	-7883.0
OR52W1	-7878.0
DAGLB	-7867.0
NTS	-7866.0
PSMB9	-7864.0
AGT	-7862.0
PTPRA	-7844.0
DKK4	-7836.0
RGS2	-7801.0
PARD3	-7779.0
ZDHHC9	-7778.0
EDN3	-7773.0
SYNGAP1	-7758.0
COL9A2	-7743.0
HDAC9	-7742.0
DUSP4	-7719.0
PRKACA	-7713.0
LAMB2	-7709.0
GFRA2	-7703.0
GPR27	-7702.0
ARHGEF40	-7699.0
CYFIP2	-7693.0
BMPR1B	-7692.0
MCF2	-7686.0
TACC3	-7685.0
RBPJ	-7670.0
ARHGEF16	-7667.0
ABR	-7655.0
SPP1	-7652.0
RTP2	-7650.0
GNAI1	-7649.0
WAS	-7636.0
CDK5R1	-7635.0
CSF2RB	-7632.0
RXFP2	-7630.0
RFNG	-7625.0
BCAR1	-7614.0
RPGRIP1L	-7611.0
PDE1C	-7601.0
FASN	-7594.0
POU2F1	-7582.0
MGLL	-7581.0
RHPN1	-7579.0
GREM2	-7567.0
S100A8	-7563.0
AKT1S1	-7553.0
DGKB	-7547.0
PTGER4	-7545.0
ADORA2B	-7537.0
RASA4	-7533.5
APOC2	-7531.5
AXIN2	-7523.0
ATF2	-7522.0
MCF2L	-7517.0
CNTN1	-7515.0
SCRIB	-7509.0
SMARCA4	-7503.0
ABHD12	-7496.0
PORCN	-7494.0
CDC20	-7493.0
PHLPP1	-7491.0
ADRA2B	-7489.0
IHH	-7487.0
PELP1	-7485.0
STRADA	-7482.0
SPC24	-7479.0
DAB2IP	-7464.0
CCDC88C	-7459.0
CASP9	-7456.0
RING1	-7450.0
PTK2B	-7442.0
RAC2	-7433.0
CHD1	-7428.0
PAK3	-7424.0
BUB3	-7420.0
NFATC1	-7417.0
MDM2	-7403.0
APOA2	-7400.0
LEO1	-7393.0
NR1H3	-7384.0
IFT52	-7374.0
STAT3	-7372.0
GRK3	-7362.0
LAMTOR5	-7358.0
RASGRP2	-7350.0
TNFAIP3	-7318.0
GNG4	-7316.0
DGKG	-7310.0
SPTBN2	-7304.0
PDGFA	-7301.0
PIP4K2A	-7295.0
ARHGEF5	-7293.0
PTPN3	-7286.0
VWF	-7285.0
CSNK1E	-7277.5
DLG4	-7276.0
TRIB1	-7257.0
VEGFD	-7250.0
CNR1	-7245.0
ITGA2B	-7222.0
ARHGAP12	-7221.0
SRMS	-7215.0
PLEKHG2	-7206.0
ARHGAP8	-7192.5
WNT10A	-7189.0
CHRM5	-7183.0
LIMK2	-7173.0
PARP1	-7161.0
GPC4	-7160.0
HDAC6	-7154.0
PRKCE	-7128.0
NEURL1	-7123.0
GNAL	-7120.0
S1PR1	-7115.0
GATAD2B	-7106.0
KIF2C	-7103.0
PIK3R2	-7098.5
VAV3	-7088.0
EPAS1	-7087.0
RTP3	-7086.0
STRAP	-7077.0
ABL1	-7066.0
TNKS2	-7057.0
LEF1	-7053.0
RGS8	-7040.0
MFNG	-7025.0
CCR9	-7000.0
CSF2RA	-6994.0
PHC1	-6987.0
DUSP7	-6984.0
GNA14	-6980.0
RBP1	-6975.0
AVPR2	-6968.0
GRAP2	-6960.0
ARHGAP35	-6956.0
NUDC	-6950.0
CDK9	-6949.0
POLR2L	-6941.0
SMAD4	-6937.0
PPARD	-6930.0
PLXND1	-6922.0
SPTB	-6905.0
CD28	-6902.0
ATN1	-6896.0
KLC3	-6887.0
ARHGEF17	-6885.0
ADCY6	-6882.0
PTGER2	-6876.0
KL	-6866.0
ITGA3	-6852.0
OR51E1	-6846.0
RASGRP3	-6839.0
AAMP	-6822.0
CNKSR1	-6817.0
PGF	-6799.0
GPR39	-6779.0
CNR2	-6771.0
ADCY4	-6759.0
APOA4	-6758.0
ARRB2	-6754.0
ECE1	-6749.0
NCOA1	-6733.0
MYH9	-6722.0
NOG	-6719.0
CCL19	-6713.0
MAP2K5	-6709.0
PRKACB	-6707.0
ICMT	-6702.0
WWP1	-6699.0
LYL1	-6681.0
AMOTL1	-6677.0
PSAP	-6675.0
TAOK1	-6649.0
EIF4EBP1	-6644.0
ARHGEF10L	-6624.0
GPAM	-6619.0
IL3RA	-6604.0
HSD17B6	-6589.0
S1PR4	-6587.0
EZH2	-6564.0
TMED2	-6563.0
PLK1	-6555.0
OTUD7B	-6540.0
KIF5A	-6521.0
RASGEF1A	-6517.0
HIF1A	-6513.0
RAPGEF3	-6504.0
TSHR	-6499.0
HTR7	-6482.0
RASAL1	-6479.0
RASAL2	-6477.0
CXCR5	-6476.0
RALGDS	-6468.5
SGK1	-6445.0
FGF10	-6441.0
PMF1	-6435.0
ADCY2	-6434.0
UBC	-6432.0
RBBP7	-6428.0
ESRP2	-6418.0
ANGPTL3	-6400.0
FURIN	-6399.0
CENPM	-6395.0
APH1B	-6387.0
EEPD1	-6385.0
SYK	-6379.0
WLS	-6377.0
TRIO	-6348.0
BCL2L11	-6346.0
LRRC7	-6336.0
PRKAB1	-6325.0
TCF4	-6313.0
SSTR1	-6304.0
C3	-6303.0
USP21	-6295.0
CHRM4	-6286.0
CLASP1	-6270.0
GPR132	-6259.0
PPP2CA	-6258.0
CER1	-6253.0
PIK3R6	-6249.0
CSNK2A2	-6247.0
MYO9A	-6231.0
RHOH	-6217.0
REEP6	-6204.0
PPP2R5A	-6197.0
FGD4	-6196.0
TCF7	-6192.0
TAC3	-6187.0
WNT6	-6186.0
LAMA3	-6177.0
MAP2K2	-6140.5
TAB1	-6122.0
KAT2A	-6099.0
ABCA1	-6097.0
RDH8	-6074.0
RAMP2	-6073.0
YWHAH	-6072.0
FZD3	-6063.0
BRAP	-6050.0
TACR1	-6047.0
ITPR3	-6046.0
PTGDR2	-6038.0
OR52I1	-6033.5
OR52I2	-6033.5
GATAD2A	-6019.0
IRAK4	-6013.0
CTNND1	-6002.0
STAM	-6001.0
PCP2	-6000.0
ST3GAL3	-5996.0
PDK4	-5994.0
PSMB2	-5987.0
SNAI1	-5985.0
FGD1	-5982.0
SYVN1	-5980.0
BCL9L	-5979.0
DYNC1I2	-5974.0
TACR3	-5973.0
DOCK7	-5972.0
OR6S1	-5969.0
USF1	-5967.0
PDK2	-5965.0
LFNG	-5964.0
AKT2	-5958.0
ACTR3	-5956.0
CD80	-5911.0
IFT122	-5901.0
CIT	-5900.0
GNG12	-5884.0
PPP1CA	-5881.0
TCF7L1	-5873.0
SKA1	-5866.0
PTPRK	-5860.0
MAG	-5858.0
WNT2B	-5857.0
PIP5K1C	-5851.0
ITPR2	-5837.0
WNT5B	-5821.0
DAAM1	-5816.0
NEFL	-5814.0
FCER2	-5807.0
AGO1	-5804.0
POLR2A	-5792.0
FGF6	-5789.0
HGS	-5785.0
TJP1	-5784.0
SUCNR1	-5782.0
COL6A5	-5779.0
FGFR2	-5766.0
FES	-5763.0
HSPB1	-5762.0
KEL	-5755.0
YWHAE	-5754.0
DLG1	-5738.0
KDR	-5733.0
CYP26B1	-5722.0
RPS6	-5720.0
WNT8B	-5701.0
AP2A1	-5700.0
GPS2	-5694.0
NOTCH1	-5689.0
RAMP1	-5656.0
P2RY6	-5637.0
JAK1	-5621.0
WWP2	-5615.0
ACTB	-5609.0
SH2B2	-5588.0
CCNE1	-5587.0
CHD3	-5584.0
AGTR1	-5580.0
KSR1	-5570.0
RHOJ	-5569.0
PSMD3	-5566.0
RHOBTB1	-5555.0
PTH1R	-5552.0
CREBBP	-5548.0
ARHGEF19	-5545.0
LRP2	-5544.0
UHMK1	-5539.0
TNRC6C	-5527.0
MYL9	-5522.0
MIR144	-5518.0
GREB1	-5516.0
SPC25	-5506.0
TACR2	-5487.0
PIK3R5	-5482.0
RANGAP1	-5473.0
DUSP6	-5469.0
WASL	-5468.0
ARHGAP32	-5460.0
MET	-5458.0
NRP2	-5449.0
TFDP1	-5433.0
ARHGAP9	-5430.0
TSC1	-5416.0
DLL4	-5410.0
OS9	-5407.0
PDE7B	-5405.0
ADAM10	-5402.0
GOLGA7	-5400.0
JAK3	-5397.0
PSMA8	-5390.0
PSMD1	-5382.0
DTX4	-5348.0
BIRC2	-5344.0
RPTOR	-5338.0
OR6K6	-5329.0
FOXH1	-5328.0
ATP2A3	-5325.0
SQSTM1	-5320.0
MAP3K11	-5319.0
TSHB	-5315.0
PAQR3	-5314.0
ARHGEF6	-5311.0
FGFR4	-5296.0
PSMB7	-5278.0
CARM1	-5274.0
FASLG	-5271.0
GNAT2	-5270.0
NOTCH3	-5268.0
SH3GL2	-5262.0
AGO2	-5246.0
PLCG1	-5242.0
RLBP1	-5232.0
IFT140	-5228.0
PTGER1	-5226.0
RXRA	-5221.0
CXCR4	-5218.0
MAP2K1	-5210.0
LAMA5	-5206.0
CASP2	-5200.0
AKAP13	-5190.0
NCOA2	-5184.0
TBL1XR1	-5183.0
WNT16	-5176.0
LAMC3	-5168.0
ARHGDIB	-5167.0
PRKCH	-5149.5
GNAO1	-5147.0
TNFSF10	-5140.0
OR6N2	-5135.0
ARHGAP11A	-5134.0
TLN1	-5122.0
DOCK3	-5112.0
RNF43	-5105.5
CCL22	-5101.0
RCVRN	-5100.0
PKN1	-5082.0
CENPF	-5077.0
ALDH8A1	-5065.0
STRN	-5063.0
TLE5	-5058.0
MEF2D	-5054.0
HECW1	-5044.0
SSTR4	-5037.0
LRP5	-5036.0
MYLIP	-5032.0
NMUR1	-5014.0
STAT5A	-5013.0
TTC21B	-5004.0
RALB	-4998.0
NET1	-4984.0
PRKAR1A	-4970.0
NR1H2	-4967.0
KIF14	-4955.0
RNF31	-4944.5
P2RY10	-4936.0
ARHGAP21	-4926.0
IRS2	-4925.0
SYDE2	-4921.0
POLR2C	-4917.0
MATK	-4914.0
VPS35	-4902.0
NSL1	-4888.0
SPTBN5	-4887.0
PDGFB	-4881.0
TRAF1	-4878.0
NPHP4	-4868.0
PIP5K1B	-4857.0
NGEF	-4851.0
PSMC3	-4849.0
CXCL9	-4847.0
BCL2L1	-4845.0
ADGRE5	-4844.0
GAL	-4837.0
POFUT1	-4833.0
COL4A2	-4819.0
HDAC4	-4813.0
ARHGAP1	-4806.0
CRHBP	-4802.0
DKK2	-4799.0
CPT1B	-4789.0
RUNX3	-4786.0
APLNR	-4782.0
ADCY10	-4780.0
RSPO4	-4776.0
H3-4	-4773.0
PML	-4770.0
PYGO1	-4769.0
NPW	-4751.0
IL6R	-4743.0
PIK3CD	-4740.0
KREMEN1	-4725.0
CTNNA1	-4715.0
RRAGB	-4707.0
GRM5	-4699.0
BRAF	-4678.0
NCOA3	-4671.0
PDE4A	-4632.0
RNF146	-4630.0
TERT	-4625.0
TJP2	-4621.5
TAS2R60	-4610.0
HEYL	-4599.0
GNB4	-4593.0
SREBF1	-4592.0
RARB	-4591.0
PTK6	-4590.0
XCR1	-4583.0
FST	-4568.0
ARHGEF38	-4562.0
PDE6A	-4543.0
SALL4	-4534.0
FNTB	-4523.5
CDH1	-4511.0
RGS3	-4491.0
FPR2	-4479.5
FPR3	-4479.5
COL4A1	-4472.0
ELMO2	-4459.0
IQGAP3	-4455.0
CCR6	-4453.0
LRAT	-4448.0
DHRS3	-4431.0
GNAI2	-4425.0
MC5R	-4388.0
DTX2	-4386.0
ADRA1D	-4383.0
SOX7	-4376.0
CASP3	-4363.0
PIP4K2B	-4348.0
MAPK6	-4338.0
PDPK1	-4325.0
PTCH2	-4298.0
ACTR2	-4296.0
SFN	-4282.0
PSMC4	-4280.0
DVL1	-4267.0
ESRP1	-4259.0
SMAD5	-4252.0
STARD13	-4246.0
TCF7L2	-4244.0
MAF1	-4232.0
ANGPT1	-4231.0
PROKR2	-4225.0
APOD	-4213.0
IGF2BP1	-4204.0
FBXW7	-4203.0
DGKH	-4197.0
GPR4	-4192.0
RAPGEF1	-4177.0
ZWINT	-4173.0
GDF2	-4169.0
GRPR	-4160.0
GZMB	-4156.0
TAS2R3	-4153.0
LEP	-4134.0
NUP133	-4126.0
PRKAG3	-4120.0
RIPK2	-4098.0
HTR1F	-4088.0
RPS6KB1	-4087.0
KAT5	-4080.0
LRIG1	-4079.0
NMT2	-4070.0
BDKRB2	-4057.0
PLCB1	-4053.0
DTX1	-4049.0
ATP6V0E2	-4048.0
ADCY1	-4044.0
ACVRL1	-4036.0
CFLAR	-4023.0
LPAR6	-4022.0
TNFRSF1A	-4011.0
FMNL3	-4009.0
ATP2A1	-4002.0
MIR206	-4000.0
VANGL2	-3997.0
SSTR3	-3984.0
PRC1	-3983.0
RHO	-3979.0
PHC3	-3939.0
MIR302A	-3935.0
GRM8	-3921.0
GHRHR	-3915.0
F11R	-3912.0
MYLK	-3905.0
DUSP16	-3902.0
CAMK2A	-3898.0
GNB1	-3895.0
BEX3	-3892.0
MCHR1	-3891.0
A2M	-3884.0
C3AR1	-3874.0
MYH11	-3840.0
OR52B2	-3822.0
NPB	-3820.0
DNAJB1	-3819.0
UTS2	-3797.0
PSMD7	-3791.0
RAG1	-3788.0
CCL4	-3785.5
JAK2	-3777.0
COL6A6	-3769.0
PHC2	-3767.0
ALDH1A1	-3766.0
HSPG2	-3764.0
GABRQ	-3752.0
TNF	-3751.0
TLE3	-3738.0
PRDM4	-3727.0
CBL	-3706.0
RPS6KA3	-3698.0
PTPN7	-3695.0
CHRM1	-3677.0
APBB1IP	-3673.0
RANBP10	-3667.0
WNT9A	-3665.0
CBX6	-3654.0
SPPL2B	-3638.0
H2BC3	-3635.0
PPP2CB	-3632.0
GNRHR	-3625.0
F2	-3616.0
H2BC12	-3610.0
IL6	-3607.0
CXCL11	-3606.0
RHOV	-3598.0
DGKK	-3596.0
DYNLL2	-3587.0
ELK1	-3586.0
PTPRJ	-3574.0
ROR1	-3567.0
GPC2	-3565.0
PTH2	-3564.0
PSEN1	-3548.0
H2AJ	-3539.0
GDI2	-3504.0
MIR106B	-3491.0
KANK1	-3487.0
PRKCQ	-3483.0
PPP2R1A	-3477.0
LAMC1	-3476.0
GPR84	-3469.0
RGR	-3467.0
MLST8	-3465.0
MIR150	-3462.0
RXFP1	-3454.0
ZW10	-3417.0
MYD88	-3411.0
GPIHBP1	-3404.0
ROCK2	-3394.0
CCR3	-3385.0
LCK	-3384.0
RASGRF1	-3383.0
ITGB3	-3380.5
ACKR4	-3367.0
SOX13	-3366.0
OR5B2	-3361.0
PPP1R12B	-3357.0
VCP	-3356.0
GRB2	-3336.0
SERPINE1	-3327.0
CLASP2	-3322.0
EDN1	-3312.0
PTGIR	-3311.0
ARHGAP39	-3310.0
LRP10	-3298.0
OR51E2	-3273.0
GSK3A	-3260.0
SGO1	-3255.0
GPR31	-3246.0
CD55	-3223.0
IFT172	-3218.0
HTR5A	-3216.0
GTF2F2	-3213.0
GTF2F1	-3198.0
GPR183	-3193.0
JAG2	-3181.0
MIR22	-3163.0
FABP7	-3155.0
HSP90AB1	-3151.0
GUCA1B	-3130.0
HEBP1	-3127.0
OR8H1	-3118.0
OR8H2	-3118.0
OR8H3	-3118.0
KDM1B	-3115.0
SPTBN4	-3105.0
PSMD4	-3087.0
RHOB	-3080.0
ATP6V1B1	-3077.0
GNG7	-3060.0
COL4A5	-3059.0
ACTN2	-3058.0
B4GALT1	-3055.0
PREX1	-3045.0
MUC20	-3040.0
GPR161	-3021.0
PSME1	-3015.0
SCD	-2989.0
SDC4	-2987.0
ABHD17A	-2953.0
WNT7B	-2916.0
CENPO	-2904.0
PYGO2	-2886.0
EVC2	-2863.0
GNA11	-2862.0
IL6ST	-2837.0
FAM13A	-2836.0
GPNMB	-2829.0
PTEN	-2811.0
HHIP	-2809.0
SOS1	-2808.0
NRG3	-2799.0
SSTR5	-2799.0
GLI3	-2791.0
PRKCG	-2783.0
KHDRBS2	-2776.0
RACGAP1	-2770.0
CCL17	-2763.0
KDM3A	-2751.0
NOTCH4	-2740.0
CYP4V2	-2726.0
GTF2A2	-2725.0
RIT1	-2710.0
LYN	-2708.0
CUL1	-2706.0
ARHGDIA	-2696.0
RANBP9	-2692.0
TYK2	-2663.0
PPP3CA	-2656.0
ADORA2A	-2639.0
YAP1	-2635.0
CCL2	-2628.0
ABI2	-2625.0
CDK5	-2600.0
DDX5	-2584.0
NFKB1	-2579.0
SMC1A	-2578.0
FLT1	-2576.0
IL5RA	-2567.0
NAB2	-2564.0
ARHGAP31	-2557.0
TRIB3	-2550.0
ARHGEF18	-2547.5
APLN	-2542.0
RBBP4	-2539.0
IQGAP2	-2507.0
RPS6KA5	-2499.0
HEY1	-2485.0
PPBP	-2477.0
PDK1	-2473.0
LPL	-2467.0
E2F3	-2466.0
SMC3	-2449.0
IQCE	-2446.0
ABCG5	-2445.0
WNT8A	-2439.0
WIF1	-2426.0
P4HB	-2423.0
P2RY2	-2415.0
GGA3	-2414.0
DNER	-2407.0
ATP6V1B2	-2392.0
OR8G1	-2378.5
OR8G5	-2378.5
EPGN	-2373.0
RSPO3	-2372.0
KNTC1	-2370.0
VEGFB	-2366.0
LINGO1	-2353.0
ADCY5	-2343.0
CUL5	-2339.0
FMNL1	-2291.0
FZD7	-2287.0
PENK	-2272.0
SPOP	-2270.0
REEP2	-2261.0
HRAS	-2253.0
NOTUM	-2252.0
MYH10	-2249.0
CX3CL1	-2245.0
FLT4	-2242.0
DNAL4	-2239.0
SH2B3	-2226.0
UCHL5	-2219.0
OR10G2	-2217.0
FPR1	-2214.0
TFDP2	-2213.0
PPP5C	-2209.0
LTB4R	-2187.0
TRAF6	-2185.0
CLIP3	-2179.0
AATF	-2176.0
PSEN2	-2171.5
TBP	-2169.0
LAMA4	-2168.0
UBA52	-2166.0
PRKCI	-2165.0
DUSP8	-2153.0
RGS1	-2147.0
MBD3	-2136.0
RCOR1	-2134.0
S100A9	-2129.0
RLN3	-2119.0
ARHGAP26	-2118.0
ADAM17	-2112.0
RELA	-2108.0
GPC3	-2107.0
KISS1	-2106.0
USP9X	-2105.0
ADM2	-2081.0
CCKAR	-2081.0
CCR4	-2081.0
GNG13	-2081.0
MIR34A	-2081.0
MIR449B	-2081.0
OPN1LW	-2081.0
OPN1MW	-2081.0
OR7E24	-2063.0
FABP6	-2049.0
LGR5	-2042.0
SDC3	-2040.0
DACT1	-2031.0
NPFF	-2026.0
RHOT2	-2024.0
RHOD	-2015.0
OR5P2	-2010.0
HGFAC	-2009.0
PPID	-2004.0
PLTP	-2003.0
APOC4	-1990.0
MAML1	-1974.0
PSMB5	-1949.0
H3-3A	-1923.0
OR6Y1	-1916.0
OR8K3	-1912.0
GABRG2	-1909.5
PSENEN	-1907.0
EGR3	-1895.0
PRKAG2	-1889.0
RARG	-1886.0
YWHAG	-1883.0
PLPPR5	-1872.0
FOSL1	-1864.0
OTULIN	-1856.0
WNT7A	-1849.0
OR2F1	-1842.5
OR2F2	-1842.5
VRK3	-1839.0
RCC2	-1836.0
GPR176	-1832.0
HDAC11	-1830.0
USP8	-1825.0
F2RL2	-1823.0
OR11A1	-1818.0
ADCY9	-1812.0
OR10K1	-1811.0
PRKCA	-1808.0
POLR2F	-1805.0
HDAC7	-1803.0
EPN1	-1801.0
CAV2	-1799.0
DSN1	-1798.0
GHSR	-1789.0
DAGLA	-1781.0
PDHA1	-1776.0
GPR55	-1771.0
OR5G3	-1752.5
CCKBR	-1743.0
PSMD10	-1732.0
RHOU	-1725.0
IL1RL1	-1724.0
CAV1	-1723.0
RIPK1	-1717.0
MAPK13	-1710.0
MAPK12	-1705.0
SOCS6	-1702.0
CBX2	-1695.0
SIRT6	-1692.0
CXCL10	-1631.0
HES1	-1625.0
EGFR	-1624.0
GATA3	-1622.0
CXCL16	-1619.0
MYL12B	-1606.0
EREG	-1562.5
GABRB2	-1562.5
OR10V1	-1562.5
OR14J1	-1562.5
OR1I1	-1562.5
OR1Q1	-1562.5
OR4A15	-1562.5
OR4P4	-1562.5
OR56B4	-1562.5
OR5M11	-1562.5
OR5P3	-1562.5
OR5T1	-1562.5
OR5T3	-1562.5
OR6C2	-1562.5
OR6C68	-1562.5
OR8B8	-1562.5
PSMB11	-1562.5
OR5AK2	-1523.0
OR5AK3P	-1523.0
TAS2R14	-1512.0
NF2	-1495.0
ARHGAP29	-1488.0
TAB2	-1485.0
METAP1	-1481.0
DHRS4	-1472.5
STK4	-1468.0
GALR1	-1455.0
AP2S1	-1453.0
NPSR1	-1445.0
WNT3	-1443.0
SP1	-1438.0
TRADD	-1426.0
PPP1R14A	-1424.0
CCND1	-1414.0
TRHR	-1407.0
WNT3A	-1406.0
RACK1	-1396.0
KDM4B	-1378.0
OMG	-1376.0
EDNRB	-1365.0
RASAL3	-1364.0
OR4B1	-1361.5
TRAT1	-1354.0
FRS2	-1340.0
GPC6	-1334.0
NDE1	-1332.0
RHOBTB2	-1304.0
PLXNB1	-1301.0
KIF2A	-1295.0
CASR	-1291.0
DLL1	-1289.0
C5AR1	-1280.0
UBE2D1	-1275.0
ARHGEF39	-1272.0
RGS13	-1258.0
TEK	-1251.0
CCR7	-1237.0
MIR19A	-1229.0
GRM6	-1224.0
OR10A3	-1219.5
OR10A6	-1219.5
HTR4	-1218.0
GPR45	-1179.0
TGFB1	-1162.0
EPS15	-1160.0
GPR143	-1156.0
YWHAB	-1151.0
USF2	-1149.0
MIR200B	-1147.0
KHDRBS1	-1146.0
GPR35	-1144.0
CXCL13	-1141.0
AGRN	-1136.0
OR9G1	-1126.0
PSMD8	-1124.0
MIR33A	-1119.0
GPSM2	-1112.0
JUNB	-1108.0
CDK5R2	-1106.0
NOTCH2	-1097.0
CDC42EP2	-1096.0
TGFA	-1093.0
DRD5	-987.0
GABRA1	-987.0
IL2	-987.0
MIR19B1	-987.0
MTNR1A	-987.0
OR10J5	-987.0
OR11G2	-987.0
OR12D3	-987.0
OR1A1	-987.0
OR1A2	-987.0
OR1J4	-987.0
OR1P1	-987.0
OR2A1	-987.0
OR2T1	-987.0
OR2W3	-987.0
OR4C16	-987.0
OR4C6	-987.0
OR51G2	-987.0
OR51Q1	-987.0
OR52E4	-987.0
OR5AL1	-987.0
OR5R1	-987.0
OR7G1	-987.0
OR8B12	-987.0
OR8B2	-987.0
OR8B3	-987.0
OR8D4	-987.0
OR9K2	-987.0
PROK1	-987.0
RBP2	-987.0
TAAR5	-987.0
TAS2R1	-987.0
ARHGAP40	-907.5
CHRM2	-907.5
FGFBP1	-907.5
OR2B11	-907.5
OR2H1	-907.5
OR2H2	-907.5
OR4D1	-907.5
OR52M1	-907.5
OR2T29	-895.0
OR2T4	-895.0
OR2T5	-895.0
DUSP9	-893.0
OR5B3	-884.0
OR4C15	-879.0
ACVR1B	-867.0
CDKN2B	-860.0
TLE2	-858.0
SPTA1	-830.0
ITCH	-823.0
KREMEN2	-783.0
ARHGEF10	-775.0
H2AZ1	-773.0
DRAP1	-757.0
PRR5	-751.0
PPP3CB	-748.0
ADAP1	-745.0
KLB	-739.0
CALCR	-738.0
OR14C36	-733.5
OR52N2	-733.5
OR56B2P	-733.5
OR7G2	-733.5
OPRL1	-730.0
TNS4	-726.0
OR5AC1	-686.0
RGS4	-680.0
SMAD1	-668.0
HCRTR1	-648.0
FOXO6	-645.0
RHOA	-640.0
CCR10	-637.0
STAM2	-609.0
RETSAT	-602.0
EGR4	-567.0
MEN1	-556.0
APOA1	-547.0
GFRA3	-543.0
BCL9	-533.0
OR2AK2	-519.5
OR5H1	-519.5
OR5H14	-519.5
OR5H15	-519.5
OR5H6	-519.5
MECOM	-508.0
PPP1R15A	-495.0
PEA15	-488.0
FOXA1	-485.0
WDR83	-482.0
ARHGEF15	-470.0
NCF4	-467.0
PDE6B	-466.0
BRS3	-461.0
ARAF	-453.0
ARHGEF33	-451.0
KLHL12	-450.0
ATP6V0D2	-449.0
YWHAZ	-416.0
GPHB5	-374.0
FZD9	-370.0
FADD	-344.0
MIR20A	-338.5
OR52D1	-338.5
NPY5R	-309.0
OR10G3	-309.0
OR4A47	-309.0
OR4F6	-309.0
OR51F2	-309.0
OR52P1P	-309.0
OR9A4	-309.0
CGA	-282.0
ATP6V1G3	-280.0
DGKD	-273.0
ARHGAP30	-260.0
AREG	-256.0
RTKN	-253.0
REEP1	-250.0
REEP5	-211.0
CAMKK2	-200.0
CXCL12	-188.0
OPRD1	-187.0
FER	-185.0
KALRN	-177.0
FOS	-162.0
EPS15L1	-152.0
RHOF	-150.0
PRKAB2	-149.0
CXXC4	-148.0
OR7D4	-133.0
OR5AN1	-121.5
OR1N1	-118.0
RGS18	-112.0
GNB5	-108.0
CALM1	-83.0
OR10AG1	-40.0
SMAD3	-28.0
GPR37L1	-27.0
ARRB1	-23.0
PDK3	-21.0
GPR65	-16.0
REEP3	-8.0
CYBA	-1.0
ERBB3	1.0
FKBP4	5.0
OR6B2	6.5
OR6B3	6.5
OR4F17	11.0
OR4F4	11.0
OR4F5	11.0
SMURF2	17.0
GRIN2B	27.0
BMP10	36.0
EIF4E	41.0
AVPR1A	53.0
CD19	55.0
RAC3	84.0
PIK3CA	85.0
GNA15	89.0
RBX1	95.0
ERLEC1	99.0
DOCK1	104.0
BCR	111.0
H2AZ2	124.0
LAMB1	139.0
TAS2R4	142.0
CALCB	231.0
CNGA1	231.0
FFAR1	231.0
IAPP	231.0
IL5	231.0
MC3R	231.0
MIR17	231.0
MIR34B	231.0
NPBWR1	231.0
OR10W1	231.0
OR13F1	231.0
OR13J1	231.0
OR1B1	231.0
OR1J1	231.0
OR1M1	231.0
OR2A14	231.0
OR2A5	231.0
OR2AP1	231.0
OR2L13	231.0
OR2Y1	231.0
OR4A16	231.0
OR4C11	231.0
OR4C12	231.0
OR4C3	231.0
OR4D11	231.0
OR4D2	231.0
OR4D6	231.0
OR4F15	231.0
OR4X2	231.0
OR51F1	231.0
OR52E2	231.0
OR52H1	231.0
OR52L1	231.0
OR52R1	231.0
OR56B1	231.0
OR5A1	231.0
OR5B17	231.0
OR5L1	231.0
OR5L2	231.0
OR5M8	231.0
OR6X1	231.0
OR8K5	231.0
OR9Q2	231.0
PIK3CB	231.0
PTH2R	231.0
RGS21	231.0
RTP1	231.0
TAAR8	231.0
TAS2R7	231.0
FGF20	321.0
FGF8	321.0
LHCGR	340.5
GIP	344.0
OR5C1	346.0
NOX3	352.0
TAS2R42	355.0
DLGAP5	369.0
FGF17	383.0
COL4A3	385.0
NMT1	404.0
FGFRL1	407.0
MAPK11	409.0
OR2B2	420.0
DVL3	421.0
RAD21	438.0
FGF1	442.0
NPY4R	446.5
OXT	449.0
PSMC5	451.0
SHOC2	454.0
PRLHR	457.0
WASF3	462.0
IL3	466.0
OR4K15	540.0
OR6C1	540.0
TAS2R19	549.0
TAS2R20	549.0
TAS2R30	549.0
TAS2R31	549.0
TAS2R43	549.0
TAS2R46	549.0
TAS2R50	549.0
DKK1	556.0
OPN4	560.0
OR8A1	563.0
APOB	573.0
ADCYAP1	576.0
FLRT1	578.0
GAS8	584.0
PPP2R5D	596.0
PIK3R3	597.5
BAMBI	601.0
KIF18A	607.0
GNRH1	612.0
F2RL1	616.0
NEURL1B	617.0
NSMAF	620.0
GALNT3	621.0
ARHGAP44	622.0
DISP2	632.0
CDC25C	650.0
PSMD14	673.0
OR5W2	676.0
GPR17	677.0
PPEF1	686.0
GRM3	693.0
MAPRE1	694.0
OR2AG1	700.0
TAC1	700.0
RHOG	709.0
ERBB2	722.0
PREX2	727.0
ATP2A2	736.0
RAF1	737.0
CBX4	766.0
SYDE1	773.0
ACTA2	781.0
IRAK1	791.0
RGS16	809.0
F2RL3	826.0
ATP6V1G1	828.0
OR52E6	842.0
OR52E8	842.0
OR8D1	842.0
FSHR	861.5
INS	861.5
OR4M1	861.5
OR4M2	861.5
OR4X1	861.5
OR51B6	861.5
OR51I2	861.5
PYY	861.5
FFAR3	896.0
OR10C1	896.0
OR10S1	896.0
OR2V1	896.0
OR4K5	896.0
OR51A2	896.0
OR51A4	896.0
OR51V1	896.0
OR52K2	896.0
OR2V2	917.5
OR2Z1	917.5
OPN5	921.0
BAD	928.0
TAS2R13	930.0
NUP107	935.0
RAP1A	937.0
NLN	943.0
RHOQ	950.0
SPRED1	953.0
CCL3	960.0
SORCS3	985.0
GNG5	992.0
KIF2B	996.0
PTBP1	1021.0
RRAGD	1040.0
EEF2K	1044.0
PDHA2	1046.0
RHPN2	1059.0
ADAM12	1062.0
SEC13	1065.0
MIR181C	1066.0
GHRH	1070.0
BIRC5	1082.0
GLI1	1088.0
OR10H1	1093.5
OR10H5	1093.5
QRFP	1095.0
APH1A	1110.0
SKP1	1129.0
UBE2M	1137.0
MIR25	1148.0
CAMK4	1172.0
NUF2	1173.0
CCNK	1182.0
GRM2	1192.0
FFAR4	1193.0
GRK2	1198.0
RGL1	1218.0
KLC2	1226.0
MOB1A	1227.0
TRIP10	1231.0
SH2B1	1236.0
SH3KBP1	1239.0
TAS2R10	1246.0
SRGAP3	1255.0
PRKCZ	1256.0
CENPN	1272.0
CTTN	1289.0
GNAT3	1292.0
RPS6KA2	1294.0
CENPU	1295.0
SSTR2	1311.0
NCKAP1	1318.0
HEY2	1323.0
HGF	1325.0
AP2M1	1347.0
SOX2	1368.0
STAP2	1378.0
XCL1	1380.5
XCL2	1380.5
OR52E5	1404.0
OR2AG2	1419.5
OR7C2	1419.5
OR8U1	1419.5
TAAR1	1419.5
GDI1	1433.0
KLK2	1449.5
KLK3	1449.5
DIAPH2	1453.0
ARHGAP33	1479.0
RBCK1	1484.0
AKT1	1488.0
ARHGAP27	1497.0
ATP6V1D	1526.0
OR4N5	1533.0
MST1	1542.0
PRKCD	1551.0
WIPF3	1562.0
GPR83	1568.0
DRD3	1587.0
EP300	1591.0
PSMD9	1596.5
TBL1X	1601.5
ADCY3	1612.0
ACVR2B	1614.0
GRK1	1615.0
ADM	1625.0
GPR15	1643.0
TRAF2	1651.0
APOM	1657.0
PDE3B	1668.0
TAB3	1681.0
JUN	1686.0
NRP1	1688.0
CBX8	1695.0
OR13C3	1717.0
PSMD12	1729.0
ATP6V1E1	1734.0
PSMB3	1735.0
CRHR1	1747.0
RYK	1765.0
LAMTOR1	1769.0
CDC14B	1785.0
NRAS	1786.0
GUCY2D	1791.0
ATP6V0A4	1802.0
SDR16C5	1807.0
CTNNB1	1809.0
HRH4	1810.0
SFPQ	1818.0
PROK2	1822.0
DGKQ	1845.0
CSN2	1876.0
FGF3	1876.0
GPRC6A	1876.0
HHAT	1886.0
PNLIP	1909.0
VAV1	1912.0
PPP1CB	1917.0
ARPC4	1946.0
GRP	1947.0
CXCL6	1966.0
GALR3	1969.0
NRTN	1970.0
RAB4B	1972.5
FRS3	1979.0
SCTR	1986.0
PSMB1	1994.0
GDNF	2000.0
PSMB4	2009.0
KIF7	2020.0
DNM3	2027.0
BOC	2047.0
OR6K3	2052.0
FZD4	2057.0
CSNK2A1	2059.5
MAPK1	2063.0
SUZ12	2083.0
CFTR	2088.0
KITLG	2099.0
LRP8	2101.0
USP13	2108.0
JUND	2121.0
KTN1	2123.0
HTR2B	2125.0
INHBB	2128.0
MST1R	2138.0
OR2T12	2143.0
OR2T33	2143.0
OR2T8	2143.0
RRAGA	2158.0
DHH	2159.0
FRAT1	2162.0
RTP4	2164.0
MC2R	2177.0
DRD2	2184.0
CRK	2198.0
TMED5	2200.0
ADCY7	2210.0
POLR2B	2214.0
DYNLL1	2216.0
NOXA1	2226.0
RAC1	2240.0
OR2AT4	2241.0
ITGAV	2243.0
PFN2	2246.0
ARHGAP4	2279.0
LATS2	2288.0
PSMD2	2314.0
OR6C70	2316.5
PSMA1	2318.0
CFL1	2322.0
OFD1	2335.0
P2RY12	2339.0
CENPQ	2367.0
OR6C76	2370.0
MIB2	2372.0
SFRP1	2381.0
RBL1	2395.0
INPP5B	2405.0
FGF4	2406.0
YY1	2410.0
TAGAP	2414.0
GAB2	2423.0
SCT	2430.0
RASA2	2440.0
NOS3	2441.0
ITGB1	2469.0
NGF	2470.0
WNT5A	2473.0
GRK5	2483.0
IL1RAP	2513.0
RGS22	2514.0
PAK2	2520.0
MAPK3	2532.0
PSMF1	2535.0
BMI1	2614.5
NCK2	2619.0
RSPO1	2627.0
ARHGAP25	2629.0
PRKCB	2630.0
APC	2637.0
MTA2	2644.0
ERCC6L	2649.0
CTSD	2669.5
FGFBP3	2673.0
YWHAQ	2683.0
FLNA	2688.0
KSR2	2694.0
WWC1	2697.0
ATP6V1E2	2719.0
CENPH	2724.0
PTPRS	2729.0
GPR68	2735.0
MMP7	2736.0
GPHA2	2779.0
BCL2	2785.0
ARHGAP23	2812.0
HCRT	2813.0
FGF2	2815.0
TBXA2R	2824.0
MAP3K7	2825.0
ADRB2	2844.0
TIAL1	2849.0
GAB1	2850.0
RXRG	2860.0
HCAR2	2866.5
HCAR3	2866.5
CRKL	2879.0
WNT1	2881.0
KIDINS220	2893.0
GRAP	2913.0
CAMKMT	2915.0
NCKAP1L	2932.0
KLC4	2935.0
LATS1	2938.0
GABRG3	2949.0
LDLR	2957.0
AMOTL2	2960.0
KAT2B	2962.0
MAPKAPK2	2978.0
SEPTIN7	2983.0
GUCY2F	3001.0
WIPF1	3006.0
PSME4	3023.0
PDE8B	3035.5
SNW1	3076.0
SPRED2	3077.0
CCR1	3082.0
ATP6AP1	3091.0
PHLPP2	3120.0
CRABP2	3127.0
FLT3	3128.0
IKBKG	3133.0
NELFB	3135.0
GNA12	3137.0
ASCL1	3141.0
PDYN	3143.0
NOXO1	3155.0
LAMTOR3	3167.0
CDCA8	3177.0
ST3GAL6	3182.0
CCL23	3192.0
STMN1	3198.0
FGF23	3205.0
SKI	3211.0
SHH	3214.0
NLK	3218.0
KCTD6	3219.0
HCAR1	3224.0
FLRT2	3256.0
POMC	3261.0
AVP	3271.0
PEBP1	3284.0
SHARPIN	3295.0
GNG3	3307.0
PCSK5	3308.0
PDE1A	3353.0
ID4	3360.0
F2R	3369.0
LPAR1	3370.0
USP7	3382.0
CPT1A	3390.0
RGS7	3418.0
DIAPH3	3419.0
GNAT1	3423.0
ERBB4	3432.0
FAM13B	3460.0
PRKAA1	3464.0
HDAC10	3474.0
POLR2I	3477.0
POLR2D	3487.0
P2RY4	3493.0
CCRL2	3501.0
MTOR	3550.0
LGR6	3551.0
HDAC2	3553.0
DLK1	3555.0
SDR9C7	3561.0
BDKRB1	3562.0
CCNT2	3571.0
TRIM27	3584.0
EGR1	3598.0
ADRB1	3612.0
GRK4	3623.0
CLTB	3636.0
PIP4K2C	3637.0
GPC1	3640.0
CBFB	3647.0
HDAC8	3649.5
CCND3	3651.0
PSMD13	3656.0
WWTR1	3663.0
MYO7A	3664.0
FABP5	3676.0
NMB	3696.0
F3	3700.0
PTPN11	3701.0
MAPK14	3711.0
RHEB	3718.0
ZDHHC21	3720.0
ATP6V1F	3727.0
GNAI3	3733.0
ATP1B4	3748.0
COL6A1	3749.0
GNG11	3752.0
B9D2	3753.0
TPH1	3766.0
HRH1	3792.0
PDE3A	3794.0
AR	3802.0
NTF4	3813.0
KIT	3843.0
ATP6V0B	3850.0
CDK2	3851.0
PPP1R1B	3853.0
PSMA5	3857.0
PTPN2	3859.0
GPR25	3869.0
PPM1A	3872.0
TGFBR2	3873.0
TCIRG1	3878.0
BCO1	3884.0
DLD	3894.0
IQGAP1	3904.0
MED1	3935.0
ADRA1B	3941.0
PSMC1	3947.0
RNF111	3951.0
TNS3	3965.0
NCBP1	3976.0
USP34	3993.0
SOCS3	3999.0
OR5I1	4012.0
SLC24A1	4032.0
IKBKB	4039.0
STK11	4058.0
DOK1	4062.0
AURKB	4064.0
SH3GL1	4081.0
PRICKLE1	4084.0
JAG1	4086.0
FKBP5	4107.0
CSF2	4120.0
CCR8	4126.0
RRAGC	4129.0
ECE2	4133.5
RAP1B	4145.0
GABRB1	4149.0
CKAP5	4160.0
CTBP1	4163.0
FGD2	4170.0
ARAP3	4175.0
PDE8A	4181.0
LYPLA1	4183.0
DUSP5	4190.0
PIK3R4	4193.0
STUB1	4214.0
ID1	4225.0
PTAFR	4229.0
ZWILCH	4234.0
GFRA1	4239.0
ALDH1A3	4259.0
PCSK6	4262.0
CCK	4270.0
AP2B1	4289.0
NEDD8	4299.0
ARAP1	4310.0
BAG4	4311.0
MAD1L1	4314.0
PDHB	4315.0
CENPT	4316.0
SRGAP1	4317.0
RAG2	4319.0
RLN2	4323.5
EPO	4329.0
MEF2C	4345.0
CBY1	4363.0
PTGES3	4369.0
PLPPR2	4371.0
GNGT2	4376.0
RALA	4380.0
SOX6	4403.0
RGS9BP	4413.0
HNRNPM	4417.0
NCKIPSD	4441.0
ITGB3BP	4443.0
RGS10	4447.0
PRKAA2	4452.0
GHRL	4454.0
BUB1B	4466.5
CHN1	4472.0
EBAG9	4476.0
PPP2R1B	4513.0
PAG1	4514.0
GTF2A1	4516.0
KHDRBS3	4518.0
NMU	4522.0
CLTC	4525.0
FOXO1	4556.0
PGR	4557.0
PIN1	4562.0
FZD8	4573.0
ADRA2A	4582.0
IER3	4585.0
CTNNBIP1	4586.0
IGF1R	4593.0
FZD1	4610.0
HBEGF	4618.0
HTR1B	4630.0
DGKA	4645.0
PTPN6	4670.0
INTU	4672.0
RAPGEF4	4676.0
WASF1	4683.0
MIR21	4691.0
OR51D1	4699.0
CAMKK1	4711.0
MAPK7	4725.0
GRB7	4726.0
LAMA1	4727.0
PDGFRA	4729.0
PLPPR4	4737.0
XIAP	4741.0
TRPC7	4748.0
PSMC6	4749.0
COL6A2	4759.0
STK3	4764.0
PFN1	4767.0
SOX17	4773.0
SPRY2	4777.0
HRH3	4786.0
FGF18	4796.0
DVL2	4800.0
CSK	4803.0
BRK1	4805.0
LRP1	4809.0
OCRL	4825.0
TAX1BP1	4835.0
CALCA	4836.0
DYNC1LI2	4837.0
TIAM2	4841.0
CCL27	4856.0
RBP3	4858.0
RAB4A	4867.0
CDC42EP3	4868.0
CILP	4877.0
MIS12	4900.0
ABHD17C	4922.0
ADRA2C	4926.0
GPR37	4931.0
POGLUT1	4942.0
MTMR4	4944.0
BTC	4946.0
MKS1	4947.0
ROCK1	4962.0
SH3GL3	4997.0
RDH10	5000.0
FZD6	5042.0
CAB39L	5045.0
EVC	5047.0
PPP3R1	5058.5
DIAPH1	5071.0
RGS9	5078.0
FGFR3	5086.0
EPOR	5088.0
FGF22	5103.0
RAMP3	5107.0
ROPN1	5110.5
SUFU	5117.0
BMPR2	5124.0
FZD5	5173.0
METAP2	5174.0
DUSP1	5190.0
HCRTR2	5199.0
RBBP5	5206.0
RASGRF2	5220.0
SPDL1	5244.0
CENPK	5248.0
CDC42EP5	5251.0
RGSL1	5265.0
OXTR	5278.0
GNA13	5282.0
OR6K2	5286.0
PSMA7	5305.0
CDC73	5336.0
ARPC1B	5378.0
PIP5K1A	5382.0
EFCAB7	5391.0
DYNC1I1	5392.0
GIPR	5394.0
ATP6V0C	5434.0
E2F5	5436.0
MRAS	5437.0
PSMA6	5445.0
PRKX	5448.5
ADGRE1	5461.0
UTS2B	5468.0
ATP6V1H	5475.0
AMH	5478.0
NR2E1	5483.0
VGF	5488.0
PDE10A	5495.0
PIK3C3	5498.0
KNL1	5503.0
RHOC	5509.5
PLCG2	5518.0
FFAR2	5519.0
NMBR	5522.0
HDAC3	5550.0
KBTBD7	5569.5
AVPR1B	5580.0
ROR2	5596.0
S1PR5	5597.0
RET	5599.0
UCN	5600.0
CYBB	5605.0
DRD4	5612.0
CNOT6L	5613.0
S1PR2	5627.0
PTPRU	5633.0
HTR2A	5650.0
H2BU1	5658.0
PTCH1	5659.0
NR5A2	5663.0
ARHGAP10	5666.0
RGS19	5668.0
PSMA2	5670.5
SPOPL	5678.0
PPP1R12A	5681.0
PSMD5	5684.0
TLR9	5692.5
WDR19	5700.0
ARHGAP28	5709.0
MOB1B	5722.0
DUSP2	5724.0
CYP26A1	5725.0
CMKLR1	5729.0
GFRA4	5742.0
SPPL2A	5745.0
SMPD2	5759.0
GPR18	5762.0
OR1F1	5776.0
EED	5777.0
ARPC3	5792.0
IL33	5812.0
VAV2	5813.0
CCNC	5816.0
PLAT	5817.0
BUB1	5820.0
CENPE	5825.0
FSTL3	5829.0
AMER1	5847.0
KRAS	5849.0
PRMT1	5858.0
FGF9	5865.0
FRK	5870.0
PMCH	5889.0
NUP160	5904.0
BAX	5925.0
XPO1	5929.0
MEMO1	5942.0
MIR26A1	5951.0
MAPK8	5956.0
ARHGEF25	5966.5
PSMD6	5980.0
ZFYVE9	5983.0
ACTG1	5986.0
RICTOR	5991.0
PTGDR	6020.0
SAV1	6025.0
FZD2	6035.0
ABI1	6048.0
WDR35	6051.0
MOV10	6056.0
BCO2	6058.0
RGL3	6085.0
SOX9	6101.0
ARHGEF12	6104.0
CENPA	6108.0
PARD6A	6114.0
SPARC	6116.0
FLRT3	6143.0
TAS2R41	6144.0
DEPDC1B	6153.0
PSMC2	6158.0
SPHK1	6185.0
SCUBE2	6192.0
MKRN1	6195.0
DZIP1	6196.0
DLC1	6197.0
DYNC2H1	6198.0
SOST	6204.0
STAG2	6209.0
BTRC	6215.0
DERL2	6219.0
CDON	6222.0
ABCG8	6224.0
NAPEPLD	6226.0
SRF	6231.0
NCF1	6238.0
LRRK2	6246.0
RCE1	6248.0
GNAZ	6253.0
FGD3	6255.0
GNB2	6264.0
OR6N1	6265.0
SMAD6	6270.0
ACKR3	6294.0
CHUK	6304.0
BMP2	6309.0
CRH	6329.0
VEGFC	6335.0
RASA1	6344.0
DLAT	6345.0
FGF7	6355.0
VIPR2	6379.0
SMURF1	6387.0
RDH12	6399.0
C5AR2	6406.0
ARHGAP18	6408.0
ARTN	6410.0
CMA1	6414.0
LAMB3	6421.0
AP2A2	6431.0
ZDHHC7	6433.0
CDK4	6438.0
OR2K2	6446.0
SDC2	6449.0
ARL2	6454.0
REEP4	6463.0
ID3	6464.0
RASGRP4	6479.0
YES1	6489.0
KIF5B	6494.0
GRIN1	6495.0
GRM1	6498.0
ICOS	6504.0
STRA6	6510.0
ARHGAP15	6512.0
RDH5	6515.0
OR4E1	6518.0
RPS6KB2	6534.0
MIR26A2	6542.0
ADRA1A	6572.0
NUP98	6576.0
ELF3	6579.0
SPTBN1	6584.0
SEL1L	6588.0
PTPN18	6594.0
GNG8	6614.0
PTPN12	6625.0
SLC38A9	6641.0
THEM4	6654.0
SHB	6666.5
ZRANB1	6677.0
CDC14A	6679.0
FGF16	6692.0
BMPR1A	6696.0
FAS	6708.0
RGS12	6733.0
KISS1R	6746.0
DYNC1LI1	6754.0
RAB6A	6765.0
MAPKAPK3	6770.0
TULP3	6772.0
PPP2R5B	6776.0
GNG2	6793.0
TGIF2	6794.0
ATP6V0E1	6801.0
H2BC11	6802.0
TAS1R1	6812.0
FLT3LG	6822.0
ADCY8	6825.0
PTPN1	6830.0
PIK3CG	6844.0
MTA3	6856.0
OPRK1	6857.0
CDKN1B	6858.0
SPINT1	6862.0
LAT	6872.0
WNT2	6877.0
CRABP1	6878.0
EGR2	6879.0
PTGFR	6884.0
FGFR1	6888.0
SOCS1	6890.0
GPSM1	6904.0
RDH14	6911.0
FN1	6913.0
H4C1	6923.5
TIAM1	6942.0
RANBP2	6945.0
P2RY1	6949.0
STRADB	6957.0
MAD2L1	6958.0
FMNL2	6964.0
VAPA	6965.0
PDHX	6966.0
LTB4R2	6967.0
CITED1	6991.0
NTRK2	6997.0
RASGRP1	7000.0
PSME2	7025.0
TNKS	7029.0
LAMTOR4	7030.0
HNRNPF	7044.0
LAMTOR2	7052.0
ARF6	7061.0
LPAR4	7063.0
ARHGAP42	7065.0
GUCA1A	7066.0
ARPC5	7069.0
SHC3	7070.0
RPE65	7074.0
MAML2	7087.0
PTPRO	7097.0
FUZ	7105.0
GNG10	7112.0
S1PR3	7127.0
TGFBR1	7130.0
ANXA1	7137.0
THBS3	7140.0
GABBR2	7146.0
NMUR2	7148.0
CAB39	7150.0
ATP6V1C1	7159.0
PPP2R5E	7165.0
USP15	7172.0
HDAC1	7175.0
CCL21	7185.0
ADCYAP1R1	7189.0
PLCB2	7190.0
IL2RA	7237.0
LPAR3	7241.0
CYLD	7243.0
SKIL	7261.0
NAB1	7262.0
PDE4B	7268.0
CHRDL1	7300.0
ABCA4	7305.0
INHBA	7307.0
SDC1	7316.0
MYL6	7318.0
DHRS9	7322.0
CYP26C1	7324.0
NCBP2	7339.0
ARHGAP36	7340.0
GRM7	7349.0
ECT2	7350.0
ST3GAL4	7352.0
LGR4	7355.0
RPS27A	7369.0
PMEPA1	7386.0
DGKI	7390.0
PDE6D	7397.0
CNKSR2	7401.0
GPBAR1	7429.0
AGO3	7448.0
RRAD	7453.0
CLIP1	7468.0
POLR2H	7476.0
CAMK2G	7477.0
APP	7480.0
ALDH1A2	7482.0
FNTA	7484.0
ACVR2A	7491.0
AGTR2	7492.0
SMAD2	7503.0
EDN2	7506.0
SPINT2	7507.0
MMP9	7518.0
ATP6V0A1	7535.0
MMP2	7540.0
MMP3	7551.0
CENPC	7561.0
BTK	7564.0
SCMH1	7581.0
ACKR2	7589.0
PRKG2	7597.0
TGIF1	7599.0
FSTL1	7606.0
SFRP2	7613.0
CCR5	7623.0
SCAI	7627.0
ARHGEF3	7632.0
PSMB8	7643.0
SHC1	7644.0
P2RY13	7646.0
SOS2	7658.0
LRP12	7671.0
TNRC6A	7675.0
FGF5	7684.0
VCL	7696.0
AHCYL1	7728.0
PSMA3	7732.0
NF1	7743.0
PKN2	7748.0
PAFAH1B1	7753.0
WNT11	7757.0
PSMB6	7759.0
CENPI	7773.0
CX3CR1	7784.0
THBS2	7788.0
CASP8	7790.0
RDH13	7793.0
KDM4C	7795.0
VPS29	7834.0
HTR1A	7853.5
HTR1D	7853.5
MIB1	7858.0
ARHGAP19	7873.5
WNT10B	7877.0
FRAT2	7883.0
GPER1	7908.0
BIRC3	7916.0
ATP6V1A	7920.0
COL9A1	7923.0
GNB3	7932.0
CUL3	7933.0
ESR2	7936.0
PNOC	7937.0
ARHGAP24	7944.0
PKN3	7945.0
DYNC1H1	7965.0
CALCRL	7971.0
VPS26A	7977.0
ARHGEF2	7980.0
DLG2	7984.0
RIT2	7986.0
ABHD17B	7989.0
DRD1	8013.0
SMO	8017.0
CYSLTR1	8025.0
PRKAR1B	8032.0
UCN2	8033.0
ULK3	8035.0
AWAT2	8046.0
ITGA2	8050.0
KIF3A	8088.0
PIK3R1	8109.0
IGF1	8112.0
OPN1SW	8117.0
ADORA3	8119.0
AXL	8124.0
SKA2	8139.0
HSD17B1	8140.0
CSNK1A1	8141.0
RSPO2	8142.0
MAPK4	8149.0
INCENP	8159.0
RNF2	8167.0
NTSR2	8169.0
CCL7	8170.0
KPNA2	8174.0
HES5	8176.0
HRH2	8194.0
IRS1	8196.0
TRPC6	8208.0
PSMA4	8213.0
GAS1	8235.0
STAG1	8250.0
CXXC5	8253.0
MC4R	8265.0
PDE6G	8266.0
POLR2G	8271.0
VEGFA	8288.0
NDEL1	8300.0
ARHGEF26	8302.0
IFT57	8304.0
AHCTF1	8307.0
BDNF	8308.0
SMPD3	8313.0
SPRY1	8321.0
SMAD7	8322.0
MAPKAP1	8323.0
RASA3	8325.0
ABHD6	8329.0
ARHGAP5	8335.0
CNGB1	8343.0
LPAR2	8362.0
RALBP1	8365.0
LRP6	8367.0
LAMA2	8370.0
IL17RD	8393.0
NRIP1	8401.0
OPN3	8414.0
ID2	8421.0
PDGFD	8426.0
CREB1	8434.0
E2F4	8446.0
CD86	8454.0
AMHR2	8466.0
GOPC	8475.5
TIA1	8497.0
CTBP2	8503.0
TRIM33	8541.0
PLA2G4A	8549.0
SPTAN1	8554.0
OTUD3	8564.0
GLP1R	8565.0
ELMO1	8567.0
WNT9B	8579.0
CLTA	8586.0
NRG4	8589.0
NOX1	8593.0
MARK3	8594.0
MYB	8599.0
NUP37	8600.0
EGF	8603.0
RDH11	8604.5
AKT3	8609.0
ARHGAP22	8611.0
KDM1A	8614.0
ATP6V1C2	8616.0
DNM1	8624.0
THBS1	8627.0
NRG2	8629.0
THBS4	8652.0
FYN	8653.0
STAT1	8658.0
NCK1	8659.0
CENPL	8678.0
RUNX1	8696.0
IL2RG	8698.5
SRY	8700.0
TRPC3	8707.0
TLE4	8719.0
RHOT1	8732.0
OPRM1	8749.0
E2F1	8755.0
RAPGEF2	8767.0
PDE7A	8851.0
GABRB3	8852.0
GRIN2D	8856.0
NTRK3	8874.0
ESR1	8895.0
ITPR1	8900.0
NTF3	8909.0
LAMC2	8913.0
PPP1CC	8925.0
RGL2	8928.0
ARPC2	8939.0
DLG3	8951.0

---

Synthesis of substrates in N-glycan biosythesis

Synthesis of substrates in N-glycan biosythesis

	1256
set	Synthesis of substrates in N-glycan biosythesis
setSize	61
pANOVA	0.000869
s.dist	0.247
p.adjustANOVA	0.0552

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NEU1	8761
ST3GAL5	8661
GNPNAT1	8416
FPGT	8260
ST8SIA5	8129
GNE	8072
GFPT2	7837
NUS1	7616
SLC35C1	7359
ST3GAL4	7352
ST3GAL1	7280
CTSA	7092
ALG5	6905
GMDS	6714
UAP1	6709
RENBP	6496
DPM2	6375
PMM1	6321
GFPT1	6299
FUOM	6173

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NEU1	8761.0
ST3GAL5	8661.0
GNPNAT1	8416.0
FPGT	8260.0
ST8SIA5	8129.0
GNE	8072.0
GFPT2	7837.0
NUS1	7616.0
SLC35C1	7359.0
ST3GAL4	7352.0
ST3GAL1	7280.0
CTSA	7092.0
ALG5	6905.0
GMDS	6714.0
UAP1	6709.0
RENBP	6496.0
DPM2	6375.0
PMM1	6321.0
GFPT1	6299.0
FUOM	6173.0
PGM3	6068.0
ST6GALNAC6	5713.5
ST8SIA1	5516.0
ST6GALNAC5	5424.0
GMPPA	5379.0
SLC17A5	5233.0
SLC35A1	4879.0
ST3GAL2	4615.0
NEU4	3618.0
NAGK	3240.0
ST3GAL6	3182.0
CMAS	2992.0
NEU3	2987.0
NPL	2528.0
ST8SIA6	2385.0
NANP	1740.0
NUDT14	1486.0
MPI	1074.0
ST6GALNAC1	531.0
ST8SIA3	512.0
DPM1	-48.0
GMPPB	-73.0
MVD	-874.0
NANS	-1294.0
ST6GALNAC4	-2240.0
DPM3	-2690.0
ST6GAL2	-2799.0
PMM2	-3168.0
DHDDS	-3360.0
ST8SIA4	-3388.0
DOLK	-4149.0
AMDHD2	-4321.5
ST6GALNAC3	-4499.0
GLB1	-4829.0
NEU2	-5224.0
FCSK	-5669.0
ST6GALNAC2	-5989.0
ST3GAL3	-5996.0
DOLPP1	-6989.0
SRD5A3	-8338.0
ST6GAL1	-8438.0

---

Plasma lipoprotein assembly

Plasma lipoprotein assembly

	881
set	Plasma lipoprotein assembly
setSize	18
pANOVA	0.000876
s.dist	-0.453
p.adjustANOVA	0.0552

Top enriched genes

Top 20 genes

GeneID	Gene Rank
APOC1	-8963.0
APOC3	-8904.0
APOE	-8836.0
MTTP	-8003.0
PRKACA	-7713.0
APOC2	-7531.5
APOA2	-7400.0
APOA4	-6758.0
PRKACB	-6707.0
ABCA1	-6097.0
A2M	-3884.0
P4HB	-2423.0
APOC4	-1990.0
APOA1	-547.0
APOB	573.0
SAR1B	1055.0
ZDHHC8	2324.0
BMP1	7235.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
APOC1	-8963.0
APOC3	-8904.0
APOE	-8836.0
MTTP	-8003.0
PRKACA	-7713.0
APOC2	-7531.5
APOA2	-7400.0
APOA4	-6758.0
PRKACB	-6707.0
ABCA1	-6097.0
A2M	-3884.0
P4HB	-2423.0
APOC4	-1990.0
APOA1	-547.0
APOB	573.0
SAR1B	1055.0
ZDHHC8	2324.0
BMP1	7235.0

---

Death Receptor Signalling

Death Receptor Signalling

	266
set	Death Receptor Signalling
setSize	132
pANOVA	0.00102
s.dist	-0.166
p.adjustANOVA	0.0613

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ARHGEF37	-8834
ARHGEF1	-8718
OBSCN	-8574
ARHGEF7	-8534
PLEKHG5	-8454
USP2	-8432
ITSN1	-8377
MAGED1	-8312
ARHGEF11	-8287
RTN4	-8274
USP4	-8272
MADD	-8225
NCSTN	-8213
NGFR	-8192
ARHGEF40	-7699
MCF2	-7686
ARHGEF16	-7667
ABR	-7655
MCF2L	-7517
TNFAIP3	-7318

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ARHGEF37	-8834.0
ARHGEF1	-8718.0
OBSCN	-8574.0
ARHGEF7	-8534.0
PLEKHG5	-8454.0
USP2	-8432.0
ITSN1	-8377.0
MAGED1	-8312.0
ARHGEF11	-8287.0
RTN4	-8274.0
USP4	-8272.0
MADD	-8225.0
NCSTN	-8213.0
NGFR	-8192.0
ARHGEF40	-7699.0
MCF2	-7686.0
ARHGEF16	-7667.0
ABR	-7655.0
MCF2L	-7517.0
TNFAIP3	-7318.0
ARHGEF5	-7293.0
PLEKHG2	-7206.0
VAV3	-7088.0
ARHGEF17	-6885.0
ARHGEF10L	-6624.0
OTUD7B	-6540.0
UBC	-6432.0
APH1B	-6387.0
TRIO	-6348.0
BCL2L11	-6346.0
USP21	-6295.0
FGD4	-6196.0
TAB1	-6122.0
FGD1	-5982.0
MAG	-5858.0
YWHAE	-5754.0
ARHGEF19	-5545.0
BIRC2	-5344.0
SQSTM1	-5320.0
ARHGEF6	-5311.0
FASLG	-5271.0
CASP2	-5200.0
AKAP13	-5190.0
TNFSF10	-5140.0
NET1	-4984.0
RNF31	-4944.5
TRAF1	-4878.0
NGEF	-4851.0
ARHGEF38	-4562.0
CASP3	-4363.0
RIPK2	-4098.0
CFLAR	-4023.0
TNFRSF1A	-4011.0
BEX3	-3892.0
TNF	-3751.0
PRDM4	-3727.0
SPPL2B	-3638.0
PSEN1	-3548.0
MYD88	-3411.0
PREX1	-3045.0
SOS1	-2808.0
ARHGDIA	-2696.0
NFKB1	-2579.0
ARHGEF18	-2547.5
LINGO1	-2353.0
TRAF6	-2185.0
CLIP3	-2179.0
AATF	-2176.0
PSEN2	-2171.5
UBA52	-2166.0
PRKCI	-2165.0
ADAM17	-2112.0
RELA	-2108.0
PSENEN	-1907.0
OTULIN	-1856.0
RIPK1	-1717.0
TAB2	-1485.0
TRADD	-1426.0
RACK1	-1396.0
OMG	-1376.0
ARHGEF39	-1272.0
ARHGEF10	-775.0
RHOA	-640.0
ARHGEF15	-470.0
ARHGEF33	-451.0
FADD	-344.0
KALRN	-177.0
NSMAF	620.0
IRAK1	791.0
BAD	928.0
SORCS3	985.0
APH1A	1110.0
RBCK1	1484.0
TRAF2	1651.0
TAB3	1681.0
VAV1	1912.0
RAC1	2240.0
NGF	2470.0
MAP3K7	2825.0
IKBKG	3133.0
SHARPIN	3295.0
HDAC2	3553.0
IKBKB	4039.0
FGD2	4170.0
BAG4	4311.0
ITGB3BP	4443.0
XIAP	4741.0
TAX1BP1	4835.0
TIAM2	4841.0
RASGRF2	5220.0
GNA13	5282.0
HDAC3	5550.0
SPPL2A	5745.0
SMPD2	5759.0
VAV2	5813.0
MAPK8	5956.0
ARHGEF12	6104.0
FGD3	6255.0
CHUK	6304.0
FAS	6708.0
TIAM1	6942.0
HDAC1	7175.0
CYLD	7243.0
ECT2	7350.0
RPS27A	7369.0
ARHGEF3	7632.0
SOS2	7658.0
CASP8	7790.0
BIRC3	7916.0
ARHGEF2	7980.0
ARHGEF26	8302.0
SMPD3	8313.0

---

Keratan sulfate degradation

Keratan sulfate degradation

	623
set	Keratan sulfate degradation
setSize	12
pANOVA	0.00108
s.dist	0.545
p.adjustANOVA	0.0613

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PRELP	8868.0
OGN	8486.0
FMOD	7779.0
HEXB	7586.0
OMD	7445.0
ACAN	7037.0
KERA	6796.0
HEXA	5131.5
GLB1L	3354.0
LUM	941.0
GNS	-359.0
GLB1	-4829.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PRELP	8868.0
OGN	8486.0
FMOD	7779.0
HEXB	7586.0
OMD	7445.0
ACAN	7037.0
KERA	6796.0
HEXA	5131.5
GLB1L	3354.0
LUM	941.0
GNS	-359.0
GLB1	-4829.0

---

Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

	122
set	Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
setSize	75
pANOVA	0.00115
s.dist	0.217
p.adjustANOVA	0.0613

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NEU1	8761
ST3GAL5	8661
GNPNAT1	8416
FPGT	8260
ST8SIA5	8129
GNE	8072
GFPT2	7837
NUS1	7616
SLC35C1	7359
ST3GAL4	7352
ST3GAL1	7280
ALG3	7136
CTSA	7092
ALG5	6905
ALG1	6760
GMDS	6714
UAP1	6709
RENBP	6496
DPM2	6375
PMM1	6321

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NEU1	8761.0
ST3GAL5	8661.0
GNPNAT1	8416.0
FPGT	8260.0
ST8SIA5	8129.0
GNE	8072.0
GFPT2	7837.0
NUS1	7616.0
SLC35C1	7359.0
ST3GAL4	7352.0
ST3GAL1	7280.0
ALG3	7136.0
CTSA	7092.0
ALG5	6905.0
ALG1	6760.0
GMDS	6714.0
UAP1	6709.0
RENBP	6496.0
DPM2	6375.0
PMM1	6321.0
GFPT1	6299.0
FUOM	6173.0
PGM3	6068.0
ALG2	6038.0
ALG9	5896.5
ST6GALNAC6	5713.5
ST8SIA1	5516.0
ST6GALNAC5	5424.0
ALG8	5423.0
GMPPA	5379.0
SLC17A5	5233.0
SLC35A1	4879.0
ST3GAL2	4615.0
RFT1	4292.5
NEU4	3618.0
NAGK	3240.0
ST3GAL6	3182.0
CMAS	2992.0
NEU3	2987.0
NPL	2528.0
ST8SIA6	2385.0
NANP	1740.0
NUDT14	1486.0
MPI	1074.0
ST6GALNAC1	531.0
ST8SIA3	512.0
ALG14	-47.0
DPM1	-48.0
GMPPB	-73.0
MVD	-874.0
NANS	-1294.0
ALG11	-2233.0
ST6GALNAC4	-2240.0
ALG12	-2380.0
DPM3	-2690.0
ST6GAL2	-2799.0
ALG10	-3026.5
ALG10B	-3026.5
PMM2	-3168.0
DHDDS	-3360.0
ST8SIA4	-3388.0
DPAGT1	-3429.0
DOLK	-4149.0
MPDU1	-4181.0
AMDHD2	-4321.5
ST6GALNAC3	-4499.0
GLB1	-4829.0
NEU2	-5224.0
FCSK	-5669.0
ST6GALNAC2	-5989.0
ST3GAL3	-5996.0
ALG6	-6909.0
DOLPP1	-6989.0
SRD5A3	-8338.0
ST6GAL1	-8438.0

---

GPCR downstream signalling

GPCR downstream signalling

	464
set	GPCR downstream signalling
setSize	829
pANOVA	0.00116
s.dist	-0.0667
p.adjustANOVA	0.0613

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GABBR1	-9063
C5	-9060
RDH16	-9052
KNG1	-9050
TAS1R2	-9042
PAK1	-9034
CRHR2	-9033
SAG	-9009
EDNRA	-8998
PDE4D	-8956
PTGER3	-8925
PDE2A	-8915
AKR1B10	-8911
APOC3	-8904
CAMK2B	-8898
PRKAR2B	-8880
PDE11A	-8842
TTR	-8839
APOE	-8836
ARHGEF37	-8834

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GABBR1	-9063.0
C5	-9060.0
RDH16	-9052.0
KNG1	-9050.0
TAS1R2	-9042.0
PAK1	-9034.0
CRHR2	-9033.0
SAG	-9009.0
EDNRA	-8998.0
PDE4D	-8956.0
PTGER3	-8925.0
PDE2A	-8915.0
AKR1B10	-8911.0
APOC3	-8904.0
CAMK2B	-8898.0
PRKAR2B	-8880.0
PDE11A	-8842.0
TTR	-8839.0
APOE	-8836.0
ARHGEF37	-8834.0
CCL28	-8774.0
RGS17	-8772.0
RRH	-8768.0
TAS1R3	-8751.0
DGKE	-8747.0
NTSR1	-8726.0
ARHGEF1	-8718.0
P2RY14	-8673.0
ADORA1	-8671.0
RPS6KA1	-8610.0
CXCR1	-8608.0
GNAS	-8601.0
RGS14	-8576.0
OBSCN	-8574.0
ARHGEF7	-8534.0
RGS5	-8529.0
RGS20	-8516.0
GRK6	-8511.0
PPP3CC	-8476.0
RGS6	-8457.0
PLEKHG5	-8454.0
CDC42	-8440.0
PDE1B	-8427.0
PLB1	-8395.0
ITSN1	-8377.0
PLCB4	-8376.0
CXCR6	-8347.0
CXCR3	-8323.0
TRH	-8317.0
CHRM3	-8311.0
ARHGEF11	-8287.0
VIPR1	-8263.0
GALR2	-8209.0
RBP4	-8178.0
DGKZ	-8155.0
GPSM3	-8134.0
PRKAR2A	-8106.0
SRC	-8095.0
VIP	-8083.0
GLP2R	-8069.0
NPY	-8050.0
LPAR5	-8048.0
NPY1R	-8014.0
PDE4C	-7992.5
ADRB3	-7987.5
QRFPR	-7977.0
PLCB3	-7957.0
NPFFR1	-7883.0
OR52W1	-7878.0
DAGLB	-7867.0
NTS	-7866.0
AGT	-7862.0
RGS2	-7801.0
EDN3	-7773.0
PRKACA	-7713.0
GPR27	-7702.0
ARHGEF40	-7699.0
MCF2	-7686.0
ARHGEF16	-7667.0
ABR	-7655.0
RTP2	-7650.0
GNAI1	-7649.0
RXFP2	-7630.0
PDE1C	-7601.0
MGLL	-7581.0
DGKB	-7547.0
PTGER4	-7545.0
ADORA2B	-7537.0
APOC2	-7531.5
MCF2L	-7517.0
ABHD12	-7496.0
ADRA2B	-7489.0
APOA2	-7400.0
GRK3	-7362.0
RASGRP2	-7350.0
GNG4	-7316.0
DGKG	-7310.0
ARHGEF5	-7293.0
CNR1	-7245.0
PLEKHG2	-7206.0
CHRM5	-7183.0
GPC4	-7160.0
PRKCE	-7128.0
GNAL	-7120.0
PIK3R2	-7098.5
VAV3	-7088.0
RTP3	-7086.0
RGS8	-7040.0
CCR9	-7000.0
GNA14	-6980.0
RBP1	-6975.0
AVPR2	-6968.0
ARHGEF17	-6885.0
ADCY6	-6882.0
PTGER2	-6876.0
OR51E1	-6846.0
GPR39	-6779.0
CNR2	-6771.0
ADCY4	-6759.0
APOA4	-6758.0
ARRB2	-6754.0
CCL19	-6713.0
PRKACB	-6707.0
PSAP	-6675.0
ARHGEF10L	-6624.0
HSD17B6	-6589.0
S1PR4	-6587.0
TSHR	-6499.0
HTR7	-6482.0
CXCR5	-6476.0
ADCY2	-6434.0
TRIO	-6348.0
SSTR1	-6304.0
C3	-6303.0
CHRM4	-6286.0
GPR132	-6259.0
PPP2CA	-6258.0
PIK3R6	-6249.0
REEP6	-6204.0
FGD4	-6196.0
TAC3	-6187.0
RDH8	-6074.0
RAMP2	-6073.0
TACR1	-6047.0
ITPR3	-6046.0
PTGDR2	-6038.0
OR52I1	-6033.5
OR52I2	-6033.5
PCP2	-6000.0
FGD1	-5982.0
TACR3	-5973.0
OR6S1	-5969.0
AKT2	-5958.0
GNG12	-5884.0
PPP1CA	-5881.0
ITPR2	-5837.0
SUCNR1	-5782.0
RAMP1	-5656.0
P2RY6	-5637.0
AGTR1	-5580.0
PTH1R	-5552.0
ARHGEF19	-5545.0
LRP2	-5544.0
TACR2	-5487.0
PIK3R5	-5482.0
PDE7B	-5405.0
OR6K6	-5329.0
TSHB	-5315.0
ARHGEF6	-5311.0
GNAT2	-5270.0
RLBP1	-5232.0
PTGER1	-5226.0
CXCR4	-5218.0
AKAP13	-5190.0
PRKCH	-5149.5
GNAO1	-5147.0
OR6N2	-5135.0
RCVRN	-5100.0
SSTR4	-5037.0
NMUR1	-5014.0
NET1	-4984.0
PRKAR1A	-4970.0
P2RY10	-4936.0
NGEF	-4851.0
CXCL9	-4847.0
GAL	-4837.0
APLNR	-4782.0
NPW	-4751.0
GRM5	-4699.0
PDE4A	-4632.0
TAS2R60	-4610.0
GNB4	-4593.0
XCR1	-4583.0
ARHGEF38	-4562.0
PDE6A	-4543.0
FNTB	-4523.5
RGS3	-4491.0
FPR2	-4479.5
FPR3	-4479.5
CCR6	-4453.0
LRAT	-4448.0
DHRS3	-4431.0
GNAI2	-4425.0
MC5R	-4388.0
ADRA1D	-4383.0
PDPK1	-4325.0
PROKR2	-4225.0
DGKH	-4197.0
GPR4	-4192.0
GRPR	-4160.0
TAS2R3	-4153.0
HTR1F	-4088.0
NMT2	-4070.0
BDKRB2	-4057.0
PLCB1	-4053.0
ADCY1	-4044.0
LPAR6	-4022.0
SSTR3	-3984.0
RHO	-3979.0
GRM8	-3921.0
GHRHR	-3915.0
CAMK2A	-3898.0
GNB1	-3895.0
MCHR1	-3891.0
C3AR1	-3874.0
OR52B2	-3822.0
NPB	-3820.0
UTS2	-3797.0
CCL4	-3785.5
HSPG2	-3764.0
RPS6KA3	-3698.0
CHRM1	-3677.0
PPP2CB	-3632.0
GNRHR	-3625.0
F2	-3616.0
CXCL11	-3606.0
DGKK	-3596.0
GPC2	-3565.0
PTH2	-3564.0
PRKCQ	-3483.0
PPP2R1A	-3477.0
GPR84	-3469.0
RGR	-3467.0
RXFP1	-3454.0
GPIHBP1	-3404.0
ROCK2	-3394.0
CCR3	-3385.0
OR5B2	-3361.0
GRB2	-3336.0
EDN1	-3312.0
PTGIR	-3311.0
LRP10	-3298.0
OR51E2	-3273.0
GPR31	-3246.0
HTR5A	-3216.0
GPR183	-3193.0
GUCA1B	-3130.0
HEBP1	-3127.0
OR8H1	-3118.0
OR8H2	-3118.0
OR8H3	-3118.0
RHOB	-3080.0
GNG7	-3060.0
PREX1	-3045.0
SDC4	-2987.0
GNA11	-2862.0
SOS1	-2808.0
SSTR5	-2799.0
PRKCG	-2783.0
CYP4V2	-2726.0
PPP3CA	-2656.0
ADORA2A	-2639.0
CDK5	-2600.0
ARHGEF18	-2547.5
APLN	-2542.0
PPBP	-2477.0
LPL	-2467.0
P2RY2	-2415.0
OR8G1	-2378.5
OR8G5	-2378.5
ADCY5	-2343.0
PENK	-2272.0
REEP2	-2261.0
HRAS	-2253.0
CX3CL1	-2245.0
OR10G2	-2217.0
FPR1	-2214.0
LTB4R	-2187.0
RGS1	-2147.0
RLN3	-2119.0
GPC3	-2107.0
KISS1	-2106.0
ADM2	-2081.0
CCKAR	-2081.0
CCR4	-2081.0
GNG13	-2081.0
OPN1LW	-2081.0
OPN1MW	-2081.0
OR7E24	-2063.0
SDC3	-2040.0
NPFF	-2026.0
OR5P2	-2010.0
OR6Y1	-1916.0
OR8K3	-1912.0
OR2F1	-1842.5
OR2F2	-1842.5
GPR176	-1832.0
F2RL2	-1823.0
OR11A1	-1818.0
ADCY9	-1812.0
OR10K1	-1811.0
PRKCA	-1808.0
GHSR	-1789.0
DAGLA	-1781.0
GPR55	-1771.0
OR5G3	-1752.5
CCKBR	-1743.0
CXCL10	-1631.0
EGFR	-1624.0
CXCL16	-1619.0
OR10V1	-1562.5
OR14J1	-1562.5
OR1I1	-1562.5
OR1Q1	-1562.5
OR4A15	-1562.5
OR4P4	-1562.5
OR56B4	-1562.5
OR5M11	-1562.5
OR5P3	-1562.5
OR5T1	-1562.5
OR5T3	-1562.5
OR6C2	-1562.5
OR6C68	-1562.5
OR8B8	-1562.5
OR5AK2	-1523.0
OR5AK3P	-1523.0
TAS2R14	-1512.0
METAP1	-1481.0
GALR1	-1455.0
NPSR1	-1445.0
TRHR	-1407.0
EDNRB	-1365.0
OR4B1	-1361.5
GPC6	-1334.0
PLXNB1	-1301.0
CASR	-1291.0
C5AR1	-1280.0
ARHGEF39	-1272.0
RGS13	-1258.0
CCR7	-1237.0
GRM6	-1224.0
OR10A3	-1219.5
OR10A6	-1219.5
HTR4	-1218.0
GPR45	-1179.0
GPR143	-1156.0
CXCL13	-1141.0
AGRN	-1136.0
OR9G1	-1126.0
GPSM2	-1112.0
DRD5	-987.0
MTNR1A	-987.0
OR10J5	-987.0
OR11G2	-987.0
OR12D3	-987.0
OR1A1	-987.0
OR1A2	-987.0
OR1J4	-987.0
OR1P1	-987.0
OR2A1	-987.0
OR2T1	-987.0
OR2W3	-987.0
OR4C16	-987.0
OR4C6	-987.0
OR51G2	-987.0
OR51Q1	-987.0
OR52E4	-987.0
OR5AL1	-987.0
OR5R1	-987.0
OR7G1	-987.0
OR8B12	-987.0
OR8B2	-987.0
OR8B3	-987.0
OR8D4	-987.0
OR9K2	-987.0
PROK1	-987.0
RBP2	-987.0
TAAR5	-987.0
TAS2R1	-987.0
CHRM2	-907.5
OR2B11	-907.5
OR2H1	-907.5
OR2H2	-907.5
OR4D1	-907.5
OR52M1	-907.5
OR2T29	-895.0
OR2T4	-895.0
OR2T5	-895.0
OR5B3	-884.0
OR4C15	-879.0
ARHGEF10	-775.0
PPP3CB	-748.0
CALCR	-738.0
OR14C36	-733.5
OR52N2	-733.5
OR56B2P	-733.5
OR7G2	-733.5
OPRL1	-730.0
OR5AC1	-686.0
RGS4	-680.0
HCRTR1	-648.0
RHOA	-640.0
CCR10	-637.0
RETSAT	-602.0
APOA1	-547.0
OR2AK2	-519.5
OR5H1	-519.5
OR5H14	-519.5
OR5H15	-519.5
OR5H6	-519.5
ARHGEF15	-470.0
PDE6B	-466.0
BRS3	-461.0
ARHGEF33	-451.0
GPHB5	-374.0
OR52D1	-338.5
NPY5R	-309.0
OR10G3	-309.0
OR4A47	-309.0
OR4F6	-309.0
OR51F2	-309.0
OR52P1P	-309.0
OR9A4	-309.0
CGA	-282.0
DGKD	-273.0
REEP1	-250.0
REEP5	-211.0
CAMKK2	-200.0
CXCL12	-188.0
OPRD1	-187.0
KALRN	-177.0
OR7D4	-133.0
OR5AN1	-121.5
OR1N1	-118.0
RGS18	-112.0
GNB5	-108.0
CALM1	-83.0
OR10AG1	-40.0
GPR37L1	-27.0
ARRB1	-23.0
GPR65	-16.0
REEP3	-8.0
OR6B2	6.5
OR6B3	6.5
OR4F17	11.0
OR4F4	11.0
OR4F5	11.0
AVPR1A	53.0
PIK3CA	85.0
GNA15	89.0
TAS2R4	142.0
CALCB	231.0
CNGA1	231.0
FFAR1	231.0
IAPP	231.0
MC3R	231.0
NPBWR1	231.0
OR10W1	231.0
OR13F1	231.0
OR13J1	231.0
OR1B1	231.0
OR1J1	231.0
OR1M1	231.0
OR2A14	231.0
OR2A5	231.0
OR2AP1	231.0
OR2L13	231.0
OR2Y1	231.0
OR4A16	231.0
OR4C11	231.0
OR4C12	231.0
OR4C3	231.0
OR4D11	231.0
OR4D2	231.0
OR4D6	231.0
OR4F15	231.0
OR4X2	231.0
OR51F1	231.0
OR52E2	231.0
OR52H1	231.0
OR52L1	231.0
OR52R1	231.0
OR56B1	231.0
OR5A1	231.0
OR5B17	231.0
OR5L1	231.0
OR5L2	231.0
OR5M8	231.0
OR6X1	231.0
OR8K5	231.0
OR9Q2	231.0
PTH2R	231.0
RGS21	231.0
RTP1	231.0
TAAR8	231.0
TAS2R7	231.0
LHCGR	340.5
GIP	344.0
OR5C1	346.0
TAS2R42	355.0
NMT1	404.0
OR2B2	420.0
NPY4R	446.5
OXT	449.0
OR4K15	540.0
OR6C1	540.0
TAS2R19	549.0
TAS2R20	549.0
TAS2R30	549.0
TAS2R31	549.0
TAS2R43	549.0
TAS2R46	549.0
TAS2R50	549.0
OPN4	560.0
OR8A1	563.0
APOB	573.0
ADCYAP1	576.0
PPP2R5D	596.0
PIK3R3	597.5
GNRH1	612.0
F2RL1	616.0
OR5W2	676.0
GPR17	677.0
PPEF1	686.0
GRM3	693.0
OR2AG1	700.0
TAC1	700.0
RGS16	809.0
F2RL3	826.0
OR52E6	842.0
OR52E8	842.0
OR8D1	842.0
FSHR	861.5
OR4M1	861.5
OR4M2	861.5
OR4X1	861.5
OR51B6	861.5
OR51I2	861.5
PYY	861.5
FFAR3	896.0
OR10C1	896.0
OR10S1	896.0
OR2V1	896.0
OR4K5	896.0
OR51A2	896.0
OR51A4	896.0
OR51V1	896.0
OR52K2	896.0
OR2V2	917.5
OR2Z1	917.5
OPN5	921.0
TAS2R13	930.0
GNG5	992.0
GHRH	1070.0
OR10H1	1093.5
OR10H5	1093.5
QRFP	1095.0
CAMK4	1172.0
GRM2	1192.0
FFAR4	1193.0
GRK2	1198.0
TAS2R10	1246.0
GNAT3	1292.0
RPS6KA2	1294.0
SSTR2	1311.0
XCL1	1380.5
XCL2	1380.5
OR52E5	1404.0
OR2AG2	1419.5
OR7C2	1419.5
OR8U1	1419.5
TAAR1	1419.5
AKT1	1488.0
OR4N5	1533.0
PRKCD	1551.0
GPR83	1568.0
DRD3	1587.0
ADCY3	1612.0
GRK1	1615.0
ADM	1625.0
GPR15	1643.0
APOM	1657.0
PDE3B	1668.0
OR13C3	1717.0
CRHR1	1747.0
NRAS	1786.0
GUCY2D	1791.0
HRH4	1810.0
PROK2	1822.0
DGKQ	1845.0
GPRC6A	1876.0
PNLIP	1909.0
VAV1	1912.0
GRP	1947.0
CXCL6	1966.0
GALR3	1969.0
SCTR	1986.0
OR6K3	2052.0
MAPK1	2063.0
LRP8	2101.0
HTR2B	2125.0
OR2T12	2143.0
OR2T33	2143.0
OR2T8	2143.0
RTP4	2164.0
MC2R	2177.0
ADCY7	2210.0
OR2AT4	2241.0
OR6C70	2316.5
P2RY12	2339.0
OR6C76	2370.0
SCT	2430.0
GRK5	2483.0
RGS22	2514.0
MAPK3	2532.0
PRKCB	2630.0
GPR68	2735.0
GPHA2	2779.0
HCRT	2813.0
TBXA2R	2824.0
ADRB2	2844.0
HCAR2	2866.5
HCAR3	2866.5
CAMKMT	2915.0
LDLR	2957.0
GUCY2F	3001.0
PDE8B	3035.5
CCR1	3082.0
GNA12	3137.0
PDYN	3143.0
CCL23	3192.0
HCAR1	3224.0
POMC	3261.0
AVP	3271.0
GNG3	3307.0
PDE1A	3353.0
F2R	3369.0
LPAR1	3370.0
RGS7	3418.0
GNAT1	3423.0
P2RY4	3493.0
SDR9C7	3561.0
BDKRB1	3562.0
ADRB1	3612.0
GRK4	3623.0
GPC1	3640.0
MYO7A	3664.0
NMB	3696.0
GNAI3	3733.0
GNG11	3752.0
HRH1	3792.0
PDE3A	3794.0
PPP1R1B	3853.0
GPR25	3869.0
BCO1	3884.0
ADRA1B	3941.0
OR5I1	4012.0
SLC24A1	4032.0
CCR8	4126.0
FGD2	4170.0
PDE8A	4181.0
PTAFR	4229.0
CCK	4270.0
RLN2	4323.5
GNGT2	4376.0
RGS9BP	4413.0
RGS10	4447.0
GHRL	4454.0
PPP2R1B	4513.0
NMU	4522.0
ADRA2A	4582.0
HBEGF	4618.0
HTR1B	4630.0
DGKA	4645.0
OR51D1	4699.0
CAMKK1	4711.0
MAPK7	4725.0
TRPC7	4748.0
LRP1	4809.0
CALCA	4836.0
TIAM2	4841.0
CCL27	4856.0
RBP3	4858.0
ADRA2C	4926.0
GPR37	4931.0
ROCK1	4962.0
RDH10	5000.0
PPP3R1	5058.5
RGS9	5078.0
RAMP3	5107.0
METAP2	5174.0
HCRTR2	5199.0
RASGRF2	5220.0
RGSL1	5265.0
OXTR	5278.0
GNA13	5282.0
OR6K2	5286.0
GIPR	5394.0
PRKX	5448.5
UTS2B	5468.0
PDE10A	5495.0
RHOC	5509.5
FFAR2	5519.0
NMBR	5522.0
AVPR1B	5580.0
S1PR5	5597.0
DRD4	5612.0
S1PR2	5627.0
HTR2A	5650.0
RGS19	5668.0
GPR18	5762.0
OR1F1	5776.0
VAV2	5813.0
KRAS	5849.0
PMCH	5889.0
ARHGEF25	5966.5
PTGDR	6020.0
BCO2	6058.0
ARHGEF12	6104.0
TAS2R41	6144.0
NAPEPLD	6226.0
GNAZ	6253.0
FGD3	6255.0
GNB2	6264.0
OR6N1	6265.0
ACKR3	6294.0
CRH	6329.0
VIPR2	6379.0
RDH12	6399.0
OR2K2	6446.0
SDC2	6449.0
REEP4	6463.0
GRM1	6498.0
STRA6	6510.0
RDH5	6515.0
OR4E1	6518.0
ADRA1A	6572.0
GNG8	6614.0
RGS12	6733.0
KISS1R	6746.0
GNG2	6793.0
TAS1R1	6812.0
ADCY8	6825.0
PIK3CG	6844.0
OPRK1	6857.0
PTGFR	6884.0
GPSM1	6904.0
TIAM1	6942.0
P2RY1	6949.0
LTB4R2	6967.0
RASGRP1	7000.0
LPAR4	7063.0
GUCA1A	7066.0
RPE65	7074.0
GNG10	7112.0
S1PR3	7127.0
ANXA1	7137.0
GABBR2	7146.0
NMUR2	7148.0
CCL21	7185.0
ADCYAP1R1	7189.0
PLCB2	7190.0
LPAR3	7241.0
PDE4B	7268.0
ABCA4	7305.0
SDC1	7316.0
DHRS9	7322.0
GRM7	7349.0
ECT2	7350.0
DGKI	7390.0
GPBAR1	7429.0
CAMK2G	7477.0
APP	7480.0
FNTA	7484.0
AGTR2	7492.0
EDN2	7506.0
MMP3	7551.0
BTK	7564.0
CCR5	7623.0
ARHGEF3	7632.0
P2RY13	7646.0
SOS2	7658.0
LRP12	7671.0
AHCYL1	7728.0
CX3CR1	7784.0
HTR1D	7853.5
GPER1	7908.0
GNB3	7932.0
PNOC	7937.0
CALCRL	7971.0
ARHGEF2	7980.0
DRD1	8013.0
CYSLTR1	8025.0
PRKAR1B	8032.0
AWAT2	8046.0
PIK3R1	8109.0
OPN1SW	8117.0
ADORA3	8119.0
HSD17B1	8140.0
NTSR2	8169.0
KPNA2	8174.0
HRH2	8194.0
TRPC6	8208.0
MC4R	8265.0
PDE6G	8266.0
ARHGEF26	8302.0
ABHD6	8329.0
CNGB1	8343.0
LPAR2	8362.0
OPN3	8414.0
CREB1	8434.0
PLA2G4A	8549.0
GLP1R	8565.0
RDH11	8604.5
AKT3	8609.0
TRPC3	8707.0
OPRM1	8749.0
PDE7A	8851.0
ITPR1	8900.0

---

Miscellaneous substrates

Miscellaneous substrates

	700
set	Miscellaneous substrates
setSize	12
pANOVA	0.00119
s.dist	-0.54
p.adjustANOVA	0.0613

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CYP2D6	-9035.5
CYP3A43	-8991.0
CYP4F2	-8108.0
CYP4A11	-7728.5
CYP4A22	-7728.5
CYP4F11	-7728.5
CYP4B1	-6651.0
CYP4F3	-4081.0
CYP2W1	-3941.0
CYP2S1	-1638.0
CYP2U1	2375.0
CYP4F22	4080.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CYP2D6	-9035.5
CYP3A43	-8991.0
CYP4F2	-8108.0
CYP4A11	-7728.5
CYP4A22	-7728.5
CYP4F11	-7728.5
CYP4B1	-6651.0
CYP4F3	-4081.0
CYP2W1	-3941.0
CYP2S1	-1638.0
CYP2U1	2375.0
CYP4F22	4080.0

---

Chylomicron remodeling

Chylomicron remodeling

	194
set	Chylomicron remodeling
setSize	10
pANOVA	0.00125
s.dist	-0.589
p.adjustANOVA	0.0613

Top enriched genes

Top 20 genes

GeneID	Gene Rank
APOC3	-8904.0
APOE	-8836.0
APOA5	-8466.0
APOC2	-7531.5
APOA2	-7400.0
APOA4	-6758.0
GPIHBP1	-3404.0
LPL	-2467.0
APOA1	-547.0
APOB	573.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
APOC3	-8904.0
APOE	-8836.0
APOA5	-8466.0
APOC2	-7531.5
APOA2	-7400.0
APOA4	-6758.0
GPIHBP1	-3404.0
LPL	-2467.0
APOA1	-547.0
APOB	573.0

---

Factors involved in megakaryocyte development and platelet production

Factors involved in megakaryocyte development and platelet production

	411
set	Factors involved in megakaryocyte development and platelet production
setSize	124
pANOVA	0.00127
s.dist	-0.168
p.adjustANOVA	0.0613

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KIFC2	-9081
KIF18B	-8985
KIF1B	-8978
KIF21A	-8950
PRKAR2B	-8880
EHD3	-8828
KIF27	-8612
KIFC1	-8600
SIN3A	-8558
CDC42	-8440
PRKAR2A	-8106
HMG20B	-7951
PRKACA	-7713
ITPK1	-7660
NFE2	-7514
KIF21B	-7488
KIF9	-7297
MFN2	-7233
ZFPM2	-7162
KIF2C	-7103

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KIFC2	-9081
KIF18B	-8985
KIF1B	-8978
KIF21A	-8950
PRKAR2B	-8880
EHD3	-8828
KIF27	-8612
KIFC1	-8600
SIN3A	-8558
CDC42	-8440
PRKAR2A	-8106
HMG20B	-7951
PRKACA	-7713
ITPK1	-7660
NFE2	-7514
KIF21B	-7488
KIF9	-7297
MFN2	-7233
ZFPM2	-7162
KIF2C	-7103
ABL1	-7066
GATA6	-6959
KLC3	-6887
CAPZB	-6870
PRKACB	-6707
KIF5A	-6521
DOCK6	-6503
KIF16B	-6282
DOCK7	-5972
DOCK9	-5908
KIF11	-5608
SH2B2	-5588
MAFK	-5510
CABLES1	-5493
IFNA1	-5355
IFNA10	-5355
IFNA14	-5355
IFNA16	-5355
IFNA17	-5355
IFNA2	-5355
IFNA21	-5355
IFNA4	-5355
IFNA5	-5355
IFNA6	-5355
IFNA7	-5355
IFNA8	-5355
KIF26A	-5302
KIF1A	-5234
KIF19	-5117
DOCK3	-5112
PRKAR1A	-4970
IRF1	-4752
EHD1	-4733
KIF20B	-4693
EHD2	-4660
KIF1C	-4619
ZFPM1	-4493
KIF26B	-3877
JAK2	-3777
GATA4	-3432
KIF20A	-3376
RACGAP1	-2770
CDK5	-2600
HBE1	-2432
KIF3C	-2283
SH2B3	-2226
RCOR1	-2134
PHF21A	-2021
H3-3A	-1923
GATA3	-1622
DOCK2	-1444
KIF2A	-1295
RAB5A	-1243
KIFAP3	-1209
AK3	-839
RAD51C	-750
DOCK1	104
MAFF	112
KIF12	517
KIF18A	607
KIF6	619
KIF2B	996
VPS45	1048
KLC2	1226
SH2B1	1236
WEE1	1357
GATA2	1911
RAC1	2240
RBSN	2306
KIF22	2377
AKAP1	2494
KLC4	2935
DOCK11	3031
DOCK4	3123
KIF4A	3248
HDAC2	3553
MICAL1	3622
GATA1	3670
MAFG	3707
CDK2	3851
AKAP10	3922
DOCK5	4260
GATA5	4604
RAD51B	5276
CAPZA2	5364
CENPE	5825
IRF2	5903
KIF5B	6494
MFN1	6573
CBX5	6715
HDAC1	7175
JMJD1C	7265
KIF15	7285
KIF23	7496
CABLES2	7630
PRKAR1B	8032
KIF3B	8041
KIF3A	8088
KIF5C	8217
KIF13B	8290
DOCK8	8423
CARMIL1	8526
MYB	8599
KDM1A	8614

---

Endosomal/Vacuolar pathway

Endosomal/Vacuolar pathway

	366
set	Endosomal/Vacuolar pathway
setSize	10
pANOVA	0.00137
s.dist	-0.585
p.adjustANOVA	0.0635

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HLA-A	-8118.5
HLA-B	-8118.5
HLA-C	-8118.5
HLA-E	-8118.5
HLA-F	-8118.5
HLA-G	-8118.5
CTSV	-4546.0
LNPEP	-4426.0
B2M	1971.0
CTSS	2396.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HLA-A	-8118.5
HLA-B	-8118.5
HLA-C	-8118.5
HLA-E	-8118.5
HLA-F	-8118.5
HLA-G	-8118.5
CTSV	-4546.0
LNPEP	-4426.0
B2M	1971.0
CTSS	2396.0

---

Platelet Aggregation (Plug Formation)

Platelet Aggregation (Plug Formation)

	886
set	Platelet Aggregation (Plug Formation)
setSize	37
pANOVA	0.00143
s.dist	-0.303
p.adjustANOVA	0.0635

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGB	-9053
MPL	-9041
FGA	-8696
THPO	-8655
PTK2	-8355
GP1BA	-8136
SRC	-8095
FGG	-8035
BCAR1	-7614
ADRA2B	-7489
RASGRP2	-7350
VWF	-7285
ITGA2B	-7222
RAPGEF3	-6504
SYK	-6379
GP5	-6277
GP9	-5163
TLN1	-5122
PDPK1	-4325
GP1BB	-3680

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGB	-9053.0
MPL	-9041.0
FGA	-8696.0
THPO	-8655.0
PTK2	-8355.0
GP1BA	-8136.0
SRC	-8095.0
FGG	-8035.0
BCAR1	-7614.0
ADRA2B	-7489.0
RASGRP2	-7350.0
VWF	-7285.0
ITGA2B	-7222.0
RAPGEF3	-6504.0
SYK	-6379.0
GP5	-6277.0
GP9	-5163.0
TLN1	-5122.0
PDPK1	-4325.0
GP1BB	-3680.0
APBB1IP	-3673.0
F2	-3616.0
ITGB3	-3380.5
GRB2	-3336.0
SOS1	-2808.0
RAP1A	937.0
AKT1	1488.0
CRK	2198.0
RAP1B	4145.0
ADRA2A	4582.0
RAPGEF4	4676.0
CSK	4803.0
ADRA2C	4926.0
PTPN1	6830.0
FN1	6913.0
RASGRP1	7000.0
SHC1	7644.0

---

Formation of the beta-catenin:TCF transactivating complex

Formation of the beta-catenin:TCF transactivating complex

	431
set	Formation of the beta-catenin:TCF transactivating complex
setSize	41
pANOVA	0.00145
s.dist	-0.288
p.adjustANOVA	0.0635

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TLE1	-9016
KMT2D	-8177
MYC	-8133
H2BC1	-8026
ASH2L	-7949
RUVBL1	-7902
AXIN2	-7523
SMARCA4	-7503
LEO1	-7393
LEF1	-7053
TCF4	-6313
TCF7	-6192
BCL9L	-5979
TCF7L1	-5873
CREBBP	-5548
RUNX3	-4786
H3-4	-4773
PYGO1	-4769
TERT	-4625
TCF7L2	-4244

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TLE1	-9016.0
KMT2D	-8177.0
MYC	-8133.0
H2BC1	-8026.0
ASH2L	-7949.0
RUVBL1	-7902.0
AXIN2	-7523.0
SMARCA4	-7503.0
LEO1	-7393.0
LEF1	-7053.0
TCF4	-6313.0
TCF7	-6192.0
BCL9L	-5979.0
TCF7L1	-5873.0
CREBBP	-5548.0
RUNX3	-4786.0
H3-4	-4773.0
PYGO1	-4769.0
TERT	-4625.0
TCF7L2	-4244.0
KAT5	-4080.0
TLE3	-3738.0
H2BC3	-3635.0
H2BC12	-3610.0
H2AJ	-3539.0
PYGO2	-2886.0
H3-3A	-1923.0
TLE2	-858.0
H2AZ1	-773.0
MEN1	-556.0
BCL9	-533.0
H2AZ2	124.0
EP300	1591.0
CTNNB1	1809.0
RBBP5	5206.0
CDC73	5336.0
H2BU1	5658.0
H2BC11	6802.0
H4C1	6923.5
HDAC1	7175.0
TLE4	8719.0

---

Regulation of lipid metabolism by PPARalpha

Regulation of lipid metabolism by PPARalpha

	1051
set	Regulation of lipid metabolism by PPARalpha
setSize	116
pANOVA	0.00158
s.dist	-0.17
p.adjustANOVA	0.0674

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SULT2A1	-9051.0
ARNT	-8977.0
MED26	-8830.5
MED13L	-8802.0
AHRR	-8688.0
PPARGC1B	-8580.0
SIN3A	-8558.0
MED16	-8539.0
NCOR2	-8506.0
PPARG	-8498.0
APOA5	-8466.0
NFYB	-8282.0
NCOR1	-8129.0
PEX11A	-8070.0
RXRB	-7956.0
AGT	-7862.0
CYP4A11	-7728.5
GLIPR1	-7664.0
CLOCK	-7607.0
APOA2	-7400.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SULT2A1	-9051.0
ARNT	-8977.0
MED26	-8830.5
MED13L	-8802.0
AHRR	-8688.0
PPARGC1B	-8580.0
SIN3A	-8558.0
MED16	-8539.0
NCOR2	-8506.0
PPARG	-8498.0
APOA5	-8466.0
NFYB	-8282.0
NCOR1	-8129.0
PEX11A	-8070.0
RXRB	-7956.0
AGT	-7862.0
CYP4A11	-7728.5
GLIPR1	-7664.0
CLOCK	-7607.0
APOA2	-7400.0
NR1H3	-7384.0
NRF1	-7330.0
MED12	-7323.0
CD36	-7248.0
MED24	-7004.0
ACOX1	-6775.0
NCOA1	-6733.0
MED15	-6643.0
MED22	-6572.0
FAM120B	-6268.0
ANGPTL4	-6243.0
MED23	-6215.0
SREBF2	-6205.0
ABCA1	-6097.0
NCOA6	-5797.0
GPS2	-5694.0
CREBBP	-5548.0
MED7	-5543.0
THRAP3	-5484.0
CARM1	-5274.0
RXRA	-5221.0
NCOA2	-5184.0
TBL1XR1	-5183.0
FABP1	-5035.0
NR1H2	-4967.0
HELZ2	-4722.0
NCOA3	-4671.0
SREBF1	-4592.0
NFYC	-4345.0
MED25	-4175.0
SIN3B	-3955.0
MED18	-3878.0
FDFT1	-3850.0
HMGCS2	-3389.0
FADS1	-3316.0
MED27	-3309.0
CPT2	-2996.0
ACSL1	-2747.0
TRIB3	-2550.0
SLC27A1	-2355.0
CDK19	-2351.0
MED30	-2156.0
SP1	-1438.0
ACADM	-1408.0
SMARCD3	-1202.0
PLIN2	-877.0
NPAS2	-672.0
APOA1	-547.0
PPARA	-247.0
CYP1A1	359.0
ME1	721.0
HMGCR	979.0
MED19	998.0
MED21	1133.0
ARNTL	1164.0
RORA	1169.0
RGL1	1218.0
ARNT2	1509.0
EP300	1591.0
TBL1X	1601.5
FHL2	1605.0
MED17	1792.5
NFYA	2215.0
MED13	2543.0
GRHL1	2566.0
AHR	2943.5
CYP7A1	3065.0
PPARGC1A	3088.0
NR1D1	3357.0
CPT1A	3390.0
HMGCS1	3682.0
MED1	3935.0
MED11	4100.0
TNFRSF21	4280.0
NR1H4	4600.0
MED31	4780.0
TGS1	4793.0
TIAM2	4841.0
MED4	5496.0
HDAC3	5550.0
CCNC	5816.0
MTF1	6150.0
TXNRD1	6305.0
G0S2	6523.0
MED6	6537.0
ALAS1	6567.0
MED29	6632.0
MED10	6668.0
MED9	7153.0
MED28	7354.0
MED20	7734.0
ESRRA	8154.0
ANKRD1	8506.0
ABCB4	8547.0
CHD9	8687.0
MED14	8916.0

---

Keratan sulfate/keratin metabolism

Keratan sulfate/keratin metabolism

	624
set	Keratan sulfate/keratin metabolism
setSize	31
pANOVA	0.00164
s.dist	0.327
p.adjustANOVA	0.0677

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PRELP	8868.0
B4GALT6	8861.0
OGN	8486.0
B3GNT3	8351.0
FMOD	7779.0
HEXB	7586.0
OMD	7445.0
ST3GAL4	7352.0
ST3GAL1	7280.0
ACAN	7037.0
KERA	6796.0
B4GALT2	5318.0
HEXA	5131.5
ST3GAL2	4615.0
B4GALT5	4469.0
B3GNT4	3805.0
GLB1L	3354.0
ST3GAL6	3182.0
B4GALT4	2489.0
CHST1	1992.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PRELP	8868.0
B4GALT6	8861.0
OGN	8486.0
B3GNT3	8351.0
FMOD	7779.0
HEXB	7586.0
OMD	7445.0
ST3GAL4	7352.0
ST3GAL1	7280.0
ACAN	7037.0
KERA	6796.0
B4GALT2	5318.0
HEXA	5131.5
ST3GAL2	4615.0
B4GALT5	4469.0
B3GNT4	3805.0
GLB1L	3354.0
ST3GAL6	3182.0
B4GALT4	2489.0
CHST1	1992.0
LUM	941.0
GNS	-359.0
SLC35D2	-885.5
CHST2	-2100.0
B4GALT3	-2173.0
B3GNT2	-2424.0
B4GALT1	-3055.0
B4GAT1	-4085.0
GLB1	-4829.0
B3GNT7	-5845.0
ST3GAL3	-5996.0

---

Intrinsic Pathway of Fibrin Clot Formation

Intrinsic Pathway of Fibrin Clot Formation

	612
set	Intrinsic Pathway of Fibrin Clot Formation
setSize	23
pANOVA	0.00177
s.dist	-0.377
p.adjustANOVA	0.0685

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KNG1	-9050.0
F10	-8579.0
F12	-8319.0
GP1BA	-8136.0
VWF	-7285.0
F11	-6531.0
GP5	-6277.0
KLKB1	-6048.0
F9	-5791.0
SERPIND1	-5751.0
GP9	-5163.0
PROC	-3962.0
A2M	-3884.0
GP1BB	-3680.0
F2	-3616.0
SERPING1	-3530.0
SERPINA5	-1562.5
PRCP	-1478.0
F8	-1310.0
SERPINC1	2277.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KNG1	-9050.0
F10	-8579.0
F12	-8319.0
GP1BA	-8136.0
VWF	-7285.0
F11	-6531.0
GP5	-6277.0
KLKB1	-6048.0
F9	-5791.0
SERPIND1	-5751.0
GP9	-5163.0
PROC	-3962.0
A2M	-3884.0
GP1BB	-3680.0
F2	-3616.0
SERPING1	-3530.0
SERPINA5	-1562.5
PRCP	-1478.0
F8	-1310.0
SERPINC1	2277.0
PROS1	4698.0
C1QBP	5377.0
SERPINE2	8181.0

---

Hemostasis

Hemostasis

	534
set	Hemostasis
setSize	582
pANOVA	0.00181
s.dist	-0.0759
p.adjustANOVA	0.0685

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KIFC2	-9081
IGHM	-9080
FGB	-9053
KNG1	-9050
IGKC	-9044
MPL	-9041
BRPF3	-9028
ITGAM	-9020
ITIH4	-9013
PLG	-9005
ITIH3	-9001
KIF18B	-8985
KIF1B	-8978
IGF2	-8965
HRG	-8962
CLU	-8960
KIF21A	-8950
PDE2A	-8915
PRKAR2B	-8880
PDE11A	-8842

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KIFC2	-9081.0
IGHM	-9080.0
FGB	-9053.0
KNG1	-9050.0
IGKC	-9044.0
MPL	-9041.0
BRPF3	-9028.0
ITGAM	-9020.0
ITIH4	-9013.0
PLG	-9005.0
ITIH3	-9001.0
KIF18B	-8985.0
KIF1B	-8978.0
IGF2	-8965.0
HRG	-8962.0
CLU	-8960.0
KIF21A	-8950.0
PDE2A	-8915.0
PRKAR2B	-8880.0
PDE11A	-8842.0
EHD3	-8828.0
DGKE	-8747.0
CFD	-8722.0
FGA	-8696.0
KCNMB2	-8691.5
KCNMB1	-8678.0
SERPINA3	-8667.0
SRGN	-8663.0
THPO	-8655.0
KIF27	-8612.0
GNAS	-8601.0
KIFC1	-8600.0
F10	-8579.0
PPP2R5C	-8572.0
CYRIB	-8567.0
SIN3A	-8558.0
ATP2B1	-8502.0
APOH	-8448.0
CDC42	-8440.0
PDE1B	-8427.0
F5	-8356.0
PTK2	-8355.0
F12	-8319.0
ANGPT2	-8277.0
L1CAM	-8233.0
CD84	-8185.0
DGKZ	-8155.0
GP1BA	-8136.0
CD74	-8112.0
PRKAR2A	-8106.0
SRC	-8095.0
ALDOA	-8055.0
FGG	-8035.0
CHID1	-7975.0
HMG20B	-7951.0
F13B	-7912.0
DAGLB	-7867.0
NOS2	-7772.0
ITGA5	-7756.0
PRKACA	-7713.0
ITPK1	-7660.0
GNAI1	-7649.0
BCAR1	-7614.0
MGLL	-7581.0
CD244	-7562.0
SELP	-7555.0
DGKB	-7547.0
NFE2	-7514.0
SLC7A10	-7506.0
ABHD12	-7496.0
ADRA2B	-7489.0
KIF21B	-7488.0
SERPINB8	-7455.0
RAC2	-7433.0
RASGRP2	-7350.0
GNG4	-7316.0
DGKG	-7310.0
APLP2	-7302.0
PDGFA	-7301.0
IRAG1	-7300.0
KIF9	-7297.0
VWF	-7285.0
STIM1	-7258.0
VEGFD	-7250.0
CD36	-7248.0
MFN2	-7233.0
ITGA2B	-7222.0
ZFPM2	-7162.0
KCNMA1	-7156.0
PRKCE	-7128.0
KIF2C	-7103.0
PIK3R2	-7098.5
VAV3	-7088.0
ABL1	-7066.0
GNA14	-6980.0
GATA6	-6959.0
KLC3	-6887.0
CAPZB	-6870.0
ITGA3	-6852.0
AAMP	-6822.0
ARRB2	-6754.0
SERPINA4	-6752.0
PRKACB	-6707.0
PSAP	-6675.0
STX4	-6665.0
P2RX6	-6557.0
F11	-6531.0
KIF5A	-6521.0
RAPGEF3	-6504.0
DOCK6	-6503.0
SYK	-6379.0
KIF16B	-6282.0
GP5	-6277.0
PPP2CA	-6258.0
PIK3R6	-6249.0
PICK1	-6219.0
PPP2R5A	-6197.0
GYPC	-6089.0
KLKB1	-6048.0
ITPR3	-6046.0
LGALS3BP	-6021.0
DOCK7	-5972.0
DOCK9	-5908.0
ITGA6	-5895.0
GNG12	-5884.0
MAG	-5858.0
ITPR2	-5837.0
F9	-5791.0
SERPIND1	-5751.0
SLC8A3	-5661.0
ACTN4	-5646.0
KIF11	-5608.0
SH2B2	-5588.0
MAFK	-5510.0
CABLES1	-5493.0
PIK3R5	-5482.0
IFNA1	-5355.0
IFNA10	-5355.0
IFNA14	-5355.0
IFNA16	-5355.0
IFNA17	-5355.0
IFNA2	-5355.0
IFNA21	-5355.0
IFNA4	-5355.0
IFNA5	-5355.0
IFNA6	-5355.0
IFNA7	-5355.0
IFNA8	-5355.0
ATP2A3	-5325.0
F7	-5305.0
KIF26A	-5302.0
PLCG1	-5242.0
ITGAX	-5237.0
KIF1A	-5234.0
IGLC1	-5196.5
IGLC2	-5196.5
IGLC3	-5196.5
IGLC7	-5196.5
IGLL1	-5196.5
GP9	-5163.0
PRKCH	-5149.5
TLN1	-5122.0
KIF19	-5117.0
DOCK3	-5112.0
PRKAR1A	-4970.0
PDGFB	-4881.0
IRF1	-4752.0
EHD1	-4733.0
KIF20B	-4693.0
ORAI1	-4684.0
EHD2	-4660.0
KIF1C	-4619.0
GNB4	-4593.0
SLC8A1	-4527.0
ZFPM1	-4493.0
GNAI2	-4425.0
CEACAM1	-4406.5
CEACAM3	-4406.5
CEACAM5	-4406.5
CEACAM6	-4406.5
CEACAM8	-4406.5
PSG1	-4406.5
PSG11	-4406.5
PSG2	-4406.5
PSG3	-4406.5
PSG4	-4406.5
PSG5	-4406.5
PSG6	-4406.5
PSG7	-4406.5
PSG8	-4406.5
PSG9	-4406.5
SLC3A2	-4375.0
PDPK1	-4325.0
P2RX4	-4302.0
ITGA4	-4297.0
ANGPT1	-4231.0
DGKH	-4197.0
CALU	-4108.0
ATP2A1	-4002.0
PDE9A	-3993.0
PROC	-3962.0
SOD1	-3928.0
GLG1	-3927.0
F11R	-3912.0
GNB1	-3895.0
GP6	-3886.0
A2M	-3884.0
STXBP2	-3879.0
KIF26B	-3877.0
JAK2	-3777.0
P2RX5	-3757.5
VTI1B	-3691.0
GP1BB	-3680.0
APBB1IP	-3673.0
PPP2CB	-3632.0
F2	-3616.0
DGKK	-3596.0
FERMT3	-3593.0
MIF	-3545.0
SERPING1	-3530.0
A1BG	-3505.0
PRKCQ	-3483.0
PPP2R1A	-3477.0
GATA4	-3432.0
LCK	-3384.0
ITGB3	-3380.5
KIF20A	-3376.0
GRB2	-3336.0
SERPINE1	-3327.0
PTGIR	-3311.0
SLC7A5	-3253.0
INPP5D	-3164.0
JAM3	-3140.0
SPN	-3134.0
RHOB	-3080.0
ITGA1	-3067.0
GNG7	-3060.0
ACTN2	-3058.0
OLA1	-3042.0
WDR1	-3013.0
SDC4	-2987.0
CD177	-2979.0
KCNMB4	-2965.0
GNA11	-2862.0
IGHV4-34	-2819.5
IGHV4-39	-2819.5
IGHV4-59	-2819.5
SOS1	-2808.0
PRKCG	-2783.0
RACGAP1	-2770.0
LYN	-2708.0
TUBA4A	-2627.0
CDK5	-2600.0
PPBP	-2477.0
PLAU	-2465.0
HBE1	-2432.0
SCG3	-2420.0
VEGFB	-2366.0
SELENOP	-2354.0
SPP2	-2337.0
KIF3C	-2283.0
HRAS	-2253.0
OLR1	-2229.0
SH2B3	-2226.0
SELPLG	-2186.0
ESAM	-2174.0
RCOR1	-2134.0
GNG13	-2081.0
SLC7A8	-2065.0
SDC3	-2040.0
TOR4A	-2039.0
PHF21A	-2021.0
TTN	-1998.0
JAM2	-1946.0
H3-3A	-1923.0
F2RL2	-1823.0
PRKCA	-1808.0
DAGLA	-1781.0
ITGAL	-1761.0
CAV1	-1723.0
GATA3	-1622.0
SERPINA5	-1562.5
ORAI2	-1505.0
PRCP	-1478.0
ATP2B2	-1475.0
HABP4	-1469.0
DOCK2	-1444.0
SLC7A9	-1420.0
F8	-1310.0
KIF2A	-1295.0
TIMP1	-1254.0
TEK	-1251.0
RAB5A	-1243.0
KIFAP3	-1209.0
ATP1B1	-1185.0
SELE	-1172.0
TGFB1	-1162.0
AK3	-839.0
FGR	-824.0
CYB5R1	-782.0
QSOX1	-760.0
RAD51C	-750.0
RHOA	-640.0
APOA1	-547.0
ITGB2	-462.0
KCNMB3	-435.0
YWHAZ	-416.0
SELL	-386.0
DGKD	-273.0
GNB5	-108.0
CALM1	-83.0
RARRES2	-81.0
CTSW	-34.0
ARRB1	-23.0
PIK3CA	85.0
GNA15	89.0
DOCK1	104.0
MAFF	112.0
CD2	119.0
CAP1	126.0
PIK3CB	231.0
IGHV7-81	372.5
KIF12	517.0
APOB	573.0
PPP2R5D	596.0
PIK3R3	597.5
KIF18A	607.0
ATP1B3	618.0
KIF6	619.0
RHOG	709.0
TSPAN7	719.5
ATP2A2	736.0
RAF1	737.0
TGFB3	801.0
F2RL3	826.0
RAP1A	937.0
IGLV6-57	991.0
GNG5	992.0
KIF2B	996.0
VPS45	1048.0
ACTN1	1114.0
SRI	1224.0
KLC2	1226.0
SH2B1	1236.0
CXADR	1249.0
PRKCZ	1256.0
JCHAIN	1276.0
GNAT3	1292.0
HGF	1325.0
WEE1	1357.0
LAMP2	1397.0
DOK2	1445.0
AKT1	1488.0
AHSG	1504.0
PRKCD	1551.0
SCCPDH	1662.0
SLC16A1	1702.0
PHACTR2	1709.0
F13A1	1711.0
NRAS	1786.0
STXBP3	1812.0
PPIL2	1825.0
DGKQ	1845.0
GATA2	1911.0
VAV1	1912.0
ENDOD1	1963.0
MMP1	2049.0
SLC16A8	2061.0
MAPK1	2063.0
CD48	2067.0
LRP8	2101.0
CRK	2198.0
TREM1	2209.0
RAC1	2240.0
ITGAV	2243.0
TIMP3	2250.0
SERPINC1	2277.0
RBSN	2306.0
LEFTY2	2311.5
CFL1	2322.0
ITGA10	2327.0
P2RY12	2339.0
NHLRC2	2355.0
KIF22	2377.0
SLC7A11	2434.0
NOS3	2441.0
CDC37L1	2449.0
ITGB1	2469.0
AKAP1	2494.0
TAGLN2	2529.0
MAPK3	2532.0
PRTN3	2547.0
SIRPA	2575.5
SIRPG	2575.5
PRKCB	2630.0
FLNA	2688.0
SLC16A3	2751.0
IGLV3-16	2760.0
IGLV3-22	2760.0
IGLV3-25	2760.0
IGLV3-27	2760.0
TBXA2R	2824.0
ORM1	2834.5
ORM2	2834.5
P2RX7	2904.0
KLC4	2935.0
ATP1B2	2959.0
THBD	3011.0
PDPN	3026.0
DOCK11	3031.0
DOCK4	3123.0
MANF	3124.0
GNA12	3137.0
ECM1	3174.0
EPCAM	3220.0
GAS6	3228.0
KIF4A	3248.0
SYTL4	3306.0
GNG3	3307.0
P2RX1	3344.0
IGKV2-30	3349.5
IGKV2D-30	3349.5
PDE1A	3353.0
F2R	3369.0
IGKV1-12	3443.5
IGKV1-16	3443.5
IGKV1-17	3443.5
IGKV1-39	3443.5
IGKV1-5	3443.5
IGKV1D-12	3443.5
IGKV1D-16	3443.5
IGKV1D-39	3443.5
APOOL	3468.0
HDAC2	3553.0
GRB14	3563.0
IGHV2-5	3567.0
IGHV2-70	3567.0
MICAL1	3622.0
GPC1	3640.0
ANGPT4	3661.0
GATA1	3670.0
F3	3700.0
PTPN11	3701.0
MAFG	3707.0
MMRN1	3708.0
MAPK14	3711.0
GNAI3	3733.0
GNG11	3752.0
FCER1G	3777.0
PDE5A	3804.0
CDK2	3851.0
PLAUR	3867.0
AKAP10	3922.0
ANXA5	4104.0
RAP1B	4145.0
CD9	4248.0
DOCK5	4260.0
ATP2B4	4304.0
CLEC3B	4318.0
VPREB3	4334.0
ISLR	4355.0
GNGT2	4376.0
MERTK	4477.0
PPP2R1B	4513.0
RAB27B	4550.0
ADRA2A	4582.0
GATA5	4604.0
DGKA	4645.0
PTPN6	4670.0
RAPGEF4	4676.0
PROS1	4698.0
GRB7	4726.0
TRPC7	4748.0
PFN1	4767.0
CSK	4803.0
ADRA2C	4926.0
S100A10	4967.0
SLC7A7	4974.0
SERPINF2	5087.0
LY6G6F	5161.5
RAD51B	5276.0
GNA13	5282.0
CAPZA2	5364.0
C1QBP	5377.0
IGKV4-1	5450.0
PDE10A	5495.0
PLCG2	5518.0
CD109	5520.0
VAV2	5813.0
PLAT	5817.0
CENPE	5825.0
KRAS	5849.0
GUCY1A2	5853.0
IRF2	5903.0
ABCC4	6019.0
FCAMR	6076.0
SERPINB6	6087.0
SPARC	6116.0
HSPA5	6121.0
CLEC1B	6137.0
SLC7A6	6179.0
FAM3C	6213.0
NOS1	6241.0
GNB2	6264.0
CD44	6282.0
LHFPL2	6310.0
VEGFC	6335.0
PCDH7	6353.0
BSG	6428.0
SDC2	6449.0
TMSB4X	6485.0
YES1	6489.0
KIF5B	6494.0
MFN1	6573.0
GNG8	6614.0
CBX5	6715.0
PPP2R5B	6776.0
GNG2	6793.0
TMX3	6827.0
PTPN1	6830.0
PIK3CG	6844.0
LAT	6872.0
FN1	6913.0
P2RY1	6949.0
RASGRP1	7000.0
PAFAH2	7055.0
GNG10	7112.0
PPP2R5E	7165.0
HDAC1	7175.0
JMJD1C	7265.0
KIF15	7285.0
SDC1	7316.0
TEX264	7338.0
PROCR	7343.0
DGKI	7390.0
LCP2	7447.0
CD63	7455.0
APP	7480.0
KIF23	7496.0
PRKG2	7597.0
CABLES2	7630.0
SHC1	7644.0
VPREB1	7668.0
ATP2B3	7695.0
VCL	7696.0
PCYOX1L	7829.0
PLEK	7931.0
GNB3	7932.0
CD47	7939.0
ALB	7970.0
PRKAR1B	8032.0
KIF3B	8041.0
ITGA2	8050.0
GTPBP2	8085.0
KIF3A	8088.0
PIK3R1	8109.0
IGF1	8112.0
SERPINE2	8181.0
TRPC6	8208.0
KIF5C	8217.0
CD99L2	8283.0
VEGFA	8288.0
KIF13B	8290.0
ABHD6	8329.0
DOCK8	8423.0
TFPI	8435.0
SLC8A2	8512.0
P2RX3	8519.0
CARMIL1	8526.0
MAGED2	8532.0
PLA2G4A	8549.0
MYB	8599.0
EGF	8603.0
KDM1A	8614.0
CD99	8621.0
THBS1	8627.0
FYN	8653.0
TRPC3	8707.0
P2RX2	8824.0
TGFB2	8828.0
PPIA	8839.5
ITPR1	8900.0

---

Chromatin modifying enzymes

Chromatin modifying enzymes

	190
set	Chromatin modifying enzymes
setSize	208
pANOVA	0.0019
s.dist	-0.125
p.adjustANOVA	0.0685

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BRPF3	-9028.0
TADA2A	-8785.0
JADE2	-8766.0
ARID1B	-8664.0
PRMT7	-8656.0
REST	-8650.0
EHMT2	-8623.0
DNMT3A	-8552.0
KMT2E	-8542.0
EP400	-8532.0
NCOR2	-8506.0
KDM4A	-8470.5
SAP130	-8463.0
SMARCE1	-8284.0
SGF29	-8256.0
WDR77	-8231.0
KMT2D	-8177.0
SMARCC1	-8164.0
KDM5A	-8149.0
NCOR1	-8129.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BRPF3	-9028.0
TADA2A	-8785.0
JADE2	-8766.0
ARID1B	-8664.0
PRMT7	-8656.0
REST	-8650.0
EHMT2	-8623.0
DNMT3A	-8552.0
KMT2E	-8542.0
EP400	-8532.0
NCOR2	-8506.0
KDM4A	-8470.5
SAP130	-8463.0
SMARCE1	-8284.0
SGF29	-8256.0
WDR77	-8231.0
KMT2D	-8177.0
SMARCC1	-8164.0
KDM5A	-8149.0
NCOR1	-8129.0
SUPT7L	-8097.0
CHD4	-8089.5
SETD2	-8046.0
H2BC1	-8026.0
DOT1L	-7989.0
HMG20B	-7951.0
ASH2L	-7949.0
RUVBL1	-7902.0
KAT6A	-7887.0
PHF20	-7796.0
BRPF1	-7733.0
CLOCK	-7607.0
ATF2	-7522.0
SMARCA4	-7503.0
SMARCC2	-7231.0
GATAD2B	-7106.0
SMARCD1	-6982.0
USP22	-6816.0
EPC1	-6787.0
NCOA1	-6733.0
VPS72	-6623.0
HCFC1	-6571.0
EZH2	-6564.0
PHF8	-6526.0
RBBP7	-6428.0
KDM5B	-6417.0
KMT5B	-6334.0
KAT8	-6306.0
SUV39H1	-6246.0
ATF7IP	-6181.0
KAT2A	-6099.0
GATAD2A	-6019.0
ING4	-5923.0
KAT6B	-5773.0
KDM2B	-5715.0
GPS2	-5694.0
MRGBP	-5670.0
ACTB	-5609.0
CHD3	-5584.0
CREBBP	-5548.0
MSL2	-5494.0
KDM6B	-5479.0
SAP30L	-5456.0
ELP5	-5428.0
DPY30	-5293.0
KMT5C	-5275.0
CARM1	-5274.0
SMARCD2	-5251.0
NCOA2	-5184.0
TBL1XR1	-5183.0
ARID1A	-5143.0
SETD1A	-4916.0
ELP6	-4910.0
SMARCA2	-4640.0
SETD1B	-4579.0
BRWD1	-4518.0
SUPT3H	-4222.0
KMT2A	-4096.5
ATXN7	-4086.0
KAT5	-4080.0
ING3	-4047.0
H2AC1	-3942.0
KDM7A	-3854.0
SMYD2	-3811.0
PHF2	-3794.0
JAK2	-3777.0
H2BC3	-3635.0
KDM4D	-3620.0
H2BC12	-3610.0
H2AJ	-3539.0
ACTL6B	-3516.0
KDM1B	-3115.0
MORF4L2	-3053.0
MBIP	-3036.0
H2AC21	-2911.0
KDM3A	-2751.0
NFKB1	-2579.0
RBBP4	-2539.0
PADI4	-2385.0
KDM2A	-2374.0
DR1	-2225.0
MBD3	-2136.0
RCOR1	-2134.0
RELA	-2108.0
NFKB2	-2096.0
ASH1L	-2058.0
PHF21A	-2021.0
MCRS1	-1868.0
EHMT1	-1807.0
TADA2B	-1722.0
RPS2	-1703.0
NSD2	-1676.0
CCND1	-1414.0
KDM4B	-1378.0
SMARCD3	-1202.0
ARID4B	-1084.0
H2AZ1	-773.0
MECOM	-508.0
PADI6	-408.0
KAT14	-261.0
SAP18	-24.0
WDR5	13.0
H2AZ2	124.0
DMAP1	334.0
AEBP2	505.0
YEATS4	770.0
ENY2	954.0
SETD3	1060.0
UTY	1097.0
JADE3	1100.0
BRD1	1135.0
KAT7	1228.0
SETD7	1248.0
ARID2	1301.0
SUDS3	1312.0
PADI3	1352.0
KMT2B	1475.0
KANSL3	1571.0
EP300	1591.0
TBL1X	1601.5
NSD1	1698.0
JMJD6	1968.0
TADA3	2021.0
PRMT5	2072.0
SUZ12	2083.0
HAT1	2127.0
RUVBL2	2438.0
ELP3	2546.0
MTA2	2644.0
PRDM9	2769.5
PRDM16	2793.0
COPRS	2905.0
KAT2B	2962.0
PADI1	3189.0
SUPT20H	3305.0
HDAC10	3474.0
HDAC2	3553.0
HDAC8	3649.5
MSL1	3703.0
JADE1	3784.0
KDM3B	4291.0
KMT5A	4560.0
SETDB1	4653.0
SMARCB1	4808.0
PAX3	4963.0
ATXN7L3	5041.0
PBRM1	5106.0
KANSL2	5109.0
RBBP5	5206.0
YEATS2	5221.0
TAF10	5463.0
HDAC3	5550.0
H2BU1	5658.0
EED	5777.0
PRMT1	5858.0
TAF6L	5958.0
ARID4A	6036.0
SETD6	6208.0
TAF12	6378.0
CDK4	6438.0
SUV39H2	6444.0
BRMS1	6472.0
PADI2	6560.0
MEAF6	6662.0
KANSL1	6678.0
TAF5L	6749.0
H2BC11	6802.0
MTA3	6856.0
H4C1	6923.5
ING5	6996.0
ELP2	7021.0
SAP30	7068.0
HDAC1	7175.0
ACTL6A	7360.0
SETDB2	7381.0
MSL3	7411.0
ELP4	7726.0
KDM4C	7795.0
ZZZ3	7850.0
PRMT3	8104.0
BRD8	8177.0
NSD3	8183.0
PRMT6	8261.0
KDM5D	8478.0
KDM1A	8614.0
OGT	8679.0
TADA1	8752.0
KDM5C	8917.0

---

Chromatin organization

Chromatin organization

	191
set	Chromatin organization
setSize	208
pANOVA	0.0019
s.dist	-0.125
p.adjustANOVA	0.0685

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BRPF3	-9028.0
TADA2A	-8785.0
JADE2	-8766.0
ARID1B	-8664.0
PRMT7	-8656.0
REST	-8650.0
EHMT2	-8623.0
DNMT3A	-8552.0
KMT2E	-8542.0
EP400	-8532.0
NCOR2	-8506.0
KDM4A	-8470.5
SAP130	-8463.0
SMARCE1	-8284.0
SGF29	-8256.0
WDR77	-8231.0
KMT2D	-8177.0
SMARCC1	-8164.0
KDM5A	-8149.0
NCOR1	-8129.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BRPF3	-9028.0
TADA2A	-8785.0
JADE2	-8766.0
ARID1B	-8664.0
PRMT7	-8656.0
REST	-8650.0
EHMT2	-8623.0
DNMT3A	-8552.0
KMT2E	-8542.0
EP400	-8532.0
NCOR2	-8506.0
KDM4A	-8470.5
SAP130	-8463.0
SMARCE1	-8284.0
SGF29	-8256.0
WDR77	-8231.0
KMT2D	-8177.0
SMARCC1	-8164.0
KDM5A	-8149.0
NCOR1	-8129.0
SUPT7L	-8097.0
CHD4	-8089.5
SETD2	-8046.0
H2BC1	-8026.0
DOT1L	-7989.0
HMG20B	-7951.0
ASH2L	-7949.0
RUVBL1	-7902.0
KAT6A	-7887.0
PHF20	-7796.0
BRPF1	-7733.0
CLOCK	-7607.0
ATF2	-7522.0
SMARCA4	-7503.0
SMARCC2	-7231.0
GATAD2B	-7106.0
SMARCD1	-6982.0
USP22	-6816.0
EPC1	-6787.0
NCOA1	-6733.0
VPS72	-6623.0
HCFC1	-6571.0
EZH2	-6564.0
PHF8	-6526.0
RBBP7	-6428.0
KDM5B	-6417.0
KMT5B	-6334.0
KAT8	-6306.0
SUV39H1	-6246.0
ATF7IP	-6181.0
KAT2A	-6099.0
GATAD2A	-6019.0
ING4	-5923.0
KAT6B	-5773.0
KDM2B	-5715.0
GPS2	-5694.0
MRGBP	-5670.0
ACTB	-5609.0
CHD3	-5584.0
CREBBP	-5548.0
MSL2	-5494.0
KDM6B	-5479.0
SAP30L	-5456.0
ELP5	-5428.0
DPY30	-5293.0
KMT5C	-5275.0
CARM1	-5274.0
SMARCD2	-5251.0
NCOA2	-5184.0
TBL1XR1	-5183.0
ARID1A	-5143.0
SETD1A	-4916.0
ELP6	-4910.0
SMARCA2	-4640.0
SETD1B	-4579.0
BRWD1	-4518.0
SUPT3H	-4222.0
KMT2A	-4096.5
ATXN7	-4086.0
KAT5	-4080.0
ING3	-4047.0
H2AC1	-3942.0
KDM7A	-3854.0
SMYD2	-3811.0
PHF2	-3794.0
JAK2	-3777.0
H2BC3	-3635.0
KDM4D	-3620.0
H2BC12	-3610.0
H2AJ	-3539.0
ACTL6B	-3516.0
KDM1B	-3115.0
MORF4L2	-3053.0
MBIP	-3036.0
H2AC21	-2911.0
KDM3A	-2751.0
NFKB1	-2579.0
RBBP4	-2539.0
PADI4	-2385.0
KDM2A	-2374.0
DR1	-2225.0
MBD3	-2136.0
RCOR1	-2134.0
RELA	-2108.0
NFKB2	-2096.0
ASH1L	-2058.0
PHF21A	-2021.0
MCRS1	-1868.0
EHMT1	-1807.0
TADA2B	-1722.0
RPS2	-1703.0
NSD2	-1676.0
CCND1	-1414.0
KDM4B	-1378.0
SMARCD3	-1202.0
ARID4B	-1084.0
H2AZ1	-773.0
MECOM	-508.0
PADI6	-408.0
KAT14	-261.0
SAP18	-24.0
WDR5	13.0
H2AZ2	124.0
DMAP1	334.0
AEBP2	505.0
YEATS4	770.0
ENY2	954.0
SETD3	1060.0
UTY	1097.0
JADE3	1100.0
BRD1	1135.0
KAT7	1228.0
SETD7	1248.0
ARID2	1301.0
SUDS3	1312.0
PADI3	1352.0
KMT2B	1475.0
KANSL3	1571.0
EP300	1591.0
TBL1X	1601.5
NSD1	1698.0
JMJD6	1968.0
TADA3	2021.0
PRMT5	2072.0
SUZ12	2083.0
HAT1	2127.0
RUVBL2	2438.0
ELP3	2546.0
MTA2	2644.0
PRDM9	2769.5
PRDM16	2793.0
COPRS	2905.0
KAT2B	2962.0
PADI1	3189.0
SUPT20H	3305.0
HDAC10	3474.0
HDAC2	3553.0
HDAC8	3649.5
MSL1	3703.0
JADE1	3784.0
KDM3B	4291.0
KMT5A	4560.0
SETDB1	4653.0
SMARCB1	4808.0
PAX3	4963.0
ATXN7L3	5041.0
PBRM1	5106.0
KANSL2	5109.0
RBBP5	5206.0
YEATS2	5221.0
TAF10	5463.0
HDAC3	5550.0
H2BU1	5658.0
EED	5777.0
PRMT1	5858.0
TAF6L	5958.0
ARID4A	6036.0
SETD6	6208.0
TAF12	6378.0
CDK4	6438.0
SUV39H2	6444.0
BRMS1	6472.0
PADI2	6560.0
MEAF6	6662.0
KANSL1	6678.0
TAF5L	6749.0
H2BC11	6802.0
MTA3	6856.0
H4C1	6923.5
ING5	6996.0
ELP2	7021.0
SAP30	7068.0
HDAC1	7175.0
ACTL6A	7360.0
SETDB2	7381.0
MSL3	7411.0
ELP4	7726.0
KDM4C	7795.0
ZZZ3	7850.0
PRMT3	8104.0
BRD8	8177.0
NSD3	8183.0
PRMT6	8261.0
KDM5D	8478.0
KDM1A	8614.0
OGT	8679.0
TADA1	8752.0
KDM5C	8917.0

---

Mitochondrial translation initiation

Mitochondrial translation initiation

	714
set	Mitochondrial translation initiation
setSize	85
pANOVA	0.00193
s.dist	0.195
p.adjustANOVA	0.0685

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MRPS14	8926
MRPS24	8562
MRPL1	8558
MRPS28	8557
MRPS18B	8556
MRPL36	8464
PTCD3	8263
DAP3	7885
MRPS35	7617
CHCHD1	7563
MRPL2	7250
MRPL17	7018
MRPL14	6867
MRPL24	6176
MRPL42	6072
MRPL45	5839
MRPS2	5800
MRPL50	5621
MRPL40	5368
MRPL22	5146

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MRPS14	8926.0
MRPS24	8562.0
MRPL1	8558.0
MRPS28	8557.0
MRPS18B	8556.0
MRPL36	8464.0
PTCD3	8263.0
DAP3	7885.0
MRPS35	7617.0
CHCHD1	7563.0
MRPL2	7250.0
MRPL17	7018.0
MRPL14	6867.0
MRPL24	6176.0
MRPL42	6072.0
MRPL45	5839.0
MRPS2	5800.0
MRPL50	5621.0
MRPL40	5368.0
MRPL22	5146.0
MTIF3	5074.0
MRPL46	4943.0
MRPL20	4603.0
MRPL47	4579.0
MRPS33	4506.0
MRPL12	4269.0
MRPS9	4258.0
GADD45GIP1	3958.0
MRPS6	3955.0
MRPL44	3931.0
MRPL3	3905.0
MRPL11	3798.0
MRPL13	3789.0
MRPL35	3604.0
MRPL32	3475.0
MRPL18	3358.0
MRPL10	3267.0
MRPL33	3221.0
MRPL43	3190.0
MRPL52	2647.0
MRPS18C	2564.0
MRPS16	2548.0
MRPL19	2510.0
MRPL27	2126.0
MRPS23	1674.0
MTIF2	1252.0
MRPL21	1230.0
MRPL15	1187.0
MRPL55	741.0
MRPL53	586.0
MRPL49	582.0
MRPL54	450.0
MRPL39	395.0
MRPS31	362.0
MRPS30	45.0
MRPS34	-44.0
MRPS5	-53.0
MRPS7	-161.0
MRPS15	-371.0
MRPS12	-431.0
MRPS11	-799.0
MRPS26	-888.0
MRPL48	-1212.0
MRPS22	-1452.0
MRPL9	-1492.0
MRPS18A	-1837.0
MRPL16	-2312.0
MRPS10	-2682.0
MRPS27	-2810.0
MRPL58	-3023.0
MRPS25	-3279.0
MTFMT	-3773.0
MRPL28	-3922.0
MRPL38	-4142.0
OXA1L	-4251.0
MRPL34	-4385.0
MRPL41	-4451.0
MRPL30	-4489.5
MRPL4	-4800.0
ERAL1	-5635.0
MRPS21	-6064.0
MRPS36	-6427.0
MRPL51	-6884.0
MRPL37	-7284.0
MRPS17	-7874.5

---

Rho GTPase cycle

Rho GTPase cycle

	1083
set	Rho GTPase cycle
setSize	134
pANOVA	0.00201
s.dist	-0.155
p.adjustANOVA	0.0685

Top enriched genes

Top 20 genes

GeneID	Gene Rank
STARD8	-9030.0
MYO9B	-8944.0
SRGAP2	-8939.0
ARHGEF37	-8834.0
ARHGAP17	-8816.0
ARHGEF1	-8718.0
OBSCN	-8574.0
OPHN1	-8557.0
ARHGEF7	-8534.0
GMIP	-8479.0
PLEKHG5	-8454.0
CDC42	-8440.0
ITSN1	-8377.0
ARAP2	-8318.0
CHN2	-8291.5
ARHGEF11	-8287.0
DEPDC7	-8183.0
ARHGAP20	-8012.0
ARHGAP6	-7915.0
ARHGEF40	-7699.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
STARD8	-9030.0
MYO9B	-8944.0
SRGAP2	-8939.0
ARHGEF37	-8834.0
ARHGAP17	-8816.0
ARHGEF1	-8718.0
OBSCN	-8574.0
OPHN1	-8557.0
ARHGEF7	-8534.0
GMIP	-8479.0
PLEKHG5	-8454.0
CDC42	-8440.0
ITSN1	-8377.0
ARAP2	-8318.0
CHN2	-8291.5
ARHGEF11	-8287.0
DEPDC7	-8183.0
ARHGAP20	-8012.0
ARHGAP6	-7915.0
ARHGEF40	-7699.0
MCF2	-7686.0
ARHGEF16	-7667.0
ABR	-7655.0
MCF2L	-7517.0
RAC2	-7433.0
ARHGEF5	-7293.0
ARHGAP12	-7221.0
PLEKHG2	-7206.0
ARHGAP8	-7192.5
PIK3R2	-7098.5
VAV3	-7088.0
ARHGAP35	-6956.0
ARHGEF17	-6885.0
ARHGEF10L	-6624.0
TRIO	-6348.0
MYO9A	-6231.0
RHOH	-6217.0
FGD4	-6196.0
FGD1	-5982.0
RHOJ	-5569.0
RHOBTB1	-5555.0
ARHGEF19	-5545.0
ARHGAP32	-5460.0
ARHGAP9	-5430.0
ARHGEF6	-5311.0
AKAP13	-5190.0
ARHGDIB	-5167.0
ARHGAP11A	-5134.0
NET1	-4984.0
ARHGAP21	-4926.0
SYDE2	-4921.0
NGEF	-4851.0
ARHGAP1	-4806.0
ARHGEF38	-4562.0
STARD13	-4246.0
A2M	-3884.0
RHOV	-3598.0
GDI2	-3504.0
ARHGAP39	-3310.0
RHOB	-3080.0
PREX1	-3045.0
FAM13A	-2836.0
SOS1	-2808.0
RACGAP1	-2770.0
ARHGDIA	-2696.0
ARHGAP31	-2557.0
ARHGEF18	-2547.5
ARHGAP26	-2118.0
RHOT2	-2024.0
RHOD	-2015.0
RHOU	-1725.0
ARHGAP29	-1488.0
RHOBTB2	-1304.0
ARHGEF39	-1272.0
ARHGAP40	-907.5
ARHGEF10	-775.0
RHOA	-640.0
ARHGEF15	-470.0
ARHGEF33	-451.0
ARHGAP30	-260.0
KALRN	-177.0
RHOF	-150.0
RAC3	84.0
BCR	111.0
ARHGAP44	622.0
RHOG	709.0
SYDE1	773.0
RHOQ	950.0
TRIP10	1231.0
SRGAP3	1255.0
GDI1	1433.0
ARHGAP33	1479.0
ARHGAP27	1497.0
VAV1	1912.0
RAC1	2240.0
ARHGAP4	2279.0
INPP5B	2405.0
TAGAP	2414.0
ARHGAP25	2629.0
ARHGAP23	2812.0
FAM13B	3460.0
FGD2	4170.0
ARAP3	4175.0
ARAP1	4310.0
SRGAP1	4317.0
CHN1	4472.0
OCRL	4825.0
TIAM2	4841.0
RASGRF2	5220.0
GNA13	5282.0
RHOC	5509.5
ARHGAP10	5666.0
ARHGAP28	5709.0
VAV2	5813.0
ARHGEF12	6104.0
DEPDC1B	6153.0
DLC1	6197.0
FGD3	6255.0
ARHGAP18	6408.0
ARHGAP15	6512.0
TIAM1	6942.0
ARHGAP42	7065.0
ARHGAP36	7340.0
ECT2	7350.0
ARHGEF3	7632.0
SOS2	7658.0
ARHGAP19	7873.5
ARHGAP24	7944.0
ARHGEF2	7980.0
ARHGEF26	8302.0
ARHGAP5	8335.0
RALBP1	8365.0
ARHGAP22	8611.0
RHOT1	8732.0

---

GRB2:SOS provides linkage to MAPK signaling for Integrins

GRB2:SOS provides linkage to MAPK signaling for Integrins

	469
set	GRB2:SOS provides linkage to MAPK signaling for Integrins
setSize	15
pANOVA	0.00205
s.dist	-0.46
p.adjustANOVA	0.0685

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGB	-9053.0
FGA	-8696.0
PTK2	-8355.0
SRC	-8095.0
FGG	-8035.0
VWF	-7285.0
ITGA2B	-7222.0
TLN1	-5122.0
APBB1IP	-3673.0
ITGB3	-3380.5
GRB2	-3336.0
SOS1	-2808.0
RAP1A	937.0
RAP1B	4145.0
FN1	6913.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGB	-9053.0
FGA	-8696.0
PTK2	-8355.0
SRC	-8095.0
FGG	-8035.0
VWF	-7285.0
ITGA2B	-7222.0
TLN1	-5122.0
APBB1IP	-3673.0
ITGB3	-3380.5
GRB2	-3336.0
SOS1	-2808.0
RAP1A	937.0
RAP1B	4145.0
FN1	6913.0

---

Aflatoxin activation and detoxification

Aflatoxin activation and detoxification

	67
set	Aflatoxin activation and detoxification
setSize	18
pANOVA	0.00205
s.dist	-0.42
p.adjustANOVA	0.0685

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CYP2A13	-9057.0
CYP3A4	-8991.0
CYP3A5	-8991.0
DPEP1	-8348.0
MGST1	-8188.0
GGT6	-7974.0
AKR7L	-7680.0
AKR7A3	-7174.0
CYP1A2	-6798.0
GGT5	-5861.0
DPEP2	-4879.0
GGT7	-3254.0
ACY1	106.5
GGT1	592.0
MGST2	2307.0
ACY3	3112.0
MGST3	4742.0
DPEP3	7176.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CYP2A13	-9057.0
CYP3A4	-8991.0
CYP3A5	-8991.0
DPEP1	-8348.0
MGST1	-8188.0
GGT6	-7974.0
AKR7L	-7680.0
AKR7A3	-7174.0
CYP1A2	-6798.0
GGT5	-5861.0
DPEP2	-4879.0
GGT7	-3254.0
ACY1	106.5
GGT1	592.0
MGST2	2307.0
ACY3	3112.0
MGST3	4742.0
DPEP3	7176.0

---

Formation of Fibrin Clot (Clotting Cascade)

Formation of Fibrin Clot (Clotting Cascade)

	421
set	Formation of Fibrin Clot (Clotting Cascade)
setSize	37
pANOVA	0.00208
s.dist	-0.292
p.adjustANOVA	0.0685

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGB	-9053
KNG1	-9050
FGA	-8696
F10	-8579
F5	-8356
F12	-8319
GP1BA	-8136
FGG	-8035
F13B	-7912
VWF	-7285
F11	-6531
GP5	-6277
KLKB1	-6048
F9	-5791
SERPIND1	-5751
F7	-5305
GP9	-5163
PROC	-3962
A2M	-3884
GP1BB	-3680

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGB	-9053.0
KNG1	-9050.0
FGA	-8696.0
F10	-8579.0
F5	-8356.0
F12	-8319.0
GP1BA	-8136.0
FGG	-8035.0
F13B	-7912.0
VWF	-7285.0
F11	-6531.0
GP5	-6277.0
KLKB1	-6048.0
F9	-5791.0
SERPIND1	-5751.0
F7	-5305.0
GP9	-5163.0
PROC	-3962.0
A2M	-3884.0
GP1BB	-3680.0
F2	-3616.0
SERPING1	-3530.0
CD177	-2979.0
SERPINA5	-1562.5
PRCP	-1478.0
F8	-1310.0
F13A1	1711.0
SERPINC1	2277.0
PRTN3	2547.0
THBD	3011.0
F2R	3369.0
F3	3700.0
PROS1	4698.0
C1QBP	5377.0
PROCR	7343.0
SERPINE2	8181.0
TFPI	8435.0

---

Protein ubiquitination

Protein ubiquitination

	929
set	Protein ubiquitination
setSize	65
pANOVA	0.00219
s.dist	-0.22
p.adjustANOVA	0.0697

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UBE2A	-8808.0
SHPRH	-8299.0
HLA-A	-8118.5
HLA-B	-8118.5
UBE2D3	-8068.0
H2BC1	-8026.0
UBE2H	-7872.0
PEX12	-7633.0
LEO1	-7393.0
UBE2E1	-6946.0
UBE2G2	-6704.0
DERL1	-6635.0
PEX13	-6630.0
UBC	-6432.0
UBE2C	-6289.0
HLTF	-5920.0
PEX10	-5886.0
UBE2W	-5708.5
UBE2S	-5679.0
RNF40	-5625.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UBE2A	-8808.0
SHPRH	-8299.0
HLA-A	-8118.5
HLA-B	-8118.5
UBE2D3	-8068.0
H2BC1	-8026.0
UBE2H	-7872.0
PEX12	-7633.0
LEO1	-7393.0
UBE2E1	-6946.0
UBE2G2	-6704.0
DERL1	-6635.0
PEX13	-6630.0
UBC	-6432.0
UBE2C	-6289.0
HLTF	-5920.0
PEX10	-5886.0
UBE2W	-5708.5
UBE2S	-5679.0
RNF40	-5625.0
UBE2R2	-5017.0
PAF1	-4974.0
UBA1	-4768.0
TMEM129	-4659.0
RTF1	-4243.0
RNF20	-4206.0
WDR61	-3743.0
PRKDC	-3663.0
H2BC3	-3635.0
H2BC12	-3610.0
UBA6	-3393.0
VCP	-3356.0
UBE2G1	-3271.0
CDC34	-2463.0
RAD18	-2341.0
UBE2V2	-2190.0
UBA52	-2166.0
USP9X	-2105.0
WAC	-2027.0
OTULIN	-1856.0
UCHL3	-1809.0
UBE2D1	-1275.0
UBE2B	-887.0
UBE2Q2	-822.0
UBE2J2	-353.0
CTR9	-85.0
BCL10	666.0
UBE2T	1282.0
UBE2K	1320.0
UBE2D2	1984.0
RRAGA	2158.0
PCNA	3070.0
PEX14	3074.0
USP7	3382.0
UBE2N	4121.5
USP5	4331.0
PEX5	4716.0
RNF152	5085.0
CDC73	5336.0
PEX2	5543.0
RNF144A	5836.0
UBE2Z	6638.0
H2BC11	6802.0
RPS27A	7369.0
SELENOS	8727.0

---

Signaling by GPCR

Signaling by GPCR

	1170
set	Signaling by GPCR
setSize	895
pANOVA	0.00226
s.dist	-0.0605
p.adjustANOVA	0.0697

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GABBR1	-9063
C5	-9060
RDH16	-9052
KNG1	-9050
TAS1R2	-9042
PAK1	-9034
CRHR2	-9033
SAG	-9009
EDNRA	-8998
PDE4D	-8956
PTGER3	-8925
PDE2A	-8915
AKR1B10	-8911
APOC3	-8904
CAMK2B	-8898
PRKAR2B	-8880
PDE11A	-8842
TTR	-8839
APOE	-8836
ARHGEF37	-8834

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GABBR1	-9063.0
C5	-9060.0
RDH16	-9052.0
KNG1	-9050.0
TAS1R2	-9042.0
PAK1	-9034.0
CRHR2	-9033.0
SAG	-9009.0
EDNRA	-8998.0
PDE4D	-8956.0
PTGER3	-8925.0
PDE2A	-8915.0
AKR1B10	-8911.0
APOC3	-8904.0
CAMK2B	-8898.0
PRKAR2B	-8880.0
PDE11A	-8842.0
TTR	-8839.0
APOE	-8836.0
ARHGEF37	-8834.0
PLPPR3	-8805.0
CCL28	-8774.0
RGS17	-8772.0
RRH	-8768.0
WNT4	-8755.0
TAS1R3	-8751.0
DGKE	-8747.0
NTSR1	-8726.0
ARHGEF1	-8718.0
P2RY14	-8673.0
ADORA1	-8671.0
RPS6KA1	-8610.0
CXCR1	-8608.0
GNAS	-8601.0
RGS14	-8576.0
OBSCN	-8574.0
ARHGEF7	-8534.0
RGS5	-8529.0
RGS20	-8516.0
GRK6	-8511.0
CCL11	-8487.0
PPP3CC	-8476.0
RGS6	-8457.0
PLEKHG5	-8454.0
CDC42	-8440.0
PDE1B	-8427.0
PLB1	-8395.0
PLPPR1	-8390.0
ITSN1	-8377.0
PLCB4	-8376.0
CXCR6	-8347.0
CXCR3	-8323.0
TRH	-8317.0
CHRM3	-8311.0
ARHGEF11	-8287.0
VIPR1	-8263.0
GALR2	-8209.0
RBP4	-8178.0
DGKZ	-8155.0
GPSM3	-8134.0
PRKAR2A	-8106.0
SRC	-8095.0
VIP	-8083.0
GLP2R	-8069.0
NPY	-8050.0
LPAR5	-8048.0
NPY1R	-8014.0
XK	-7994.0
PDE4C	-7992.5
ADRB3	-7987.5
QRFPR	-7977.0
PLCB3	-7957.0
NPFFR1	-7883.0
OR52W1	-7878.0
DAGLB	-7867.0
NTS	-7866.0
AGT	-7862.0
RGS2	-7801.0
EDN3	-7773.0
PRKACA	-7713.0
GPR27	-7702.0
ARHGEF40	-7699.0
MCF2	-7686.0
ARHGEF16	-7667.0
ABR	-7655.0
RTP2	-7650.0
GNAI1	-7649.0
RXFP2	-7630.0
PDE1C	-7601.0
MGLL	-7581.0
DGKB	-7547.0
PTGER4	-7545.0
ADORA2B	-7537.0
APOC2	-7531.5
MCF2L	-7517.0
ABHD12	-7496.0
ADRA2B	-7489.0
IHH	-7487.0
APOA2	-7400.0
GRK3	-7362.0
RASGRP2	-7350.0
GNG4	-7316.0
DGKG	-7310.0
ARHGEF5	-7293.0
CNR1	-7245.0
PLEKHG2	-7206.0
WNT10A	-7189.0
CHRM5	-7183.0
GPC4	-7160.0
PRKCE	-7128.0
GNAL	-7120.0
S1PR1	-7115.0
PIK3R2	-7098.5
VAV3	-7088.0
RTP3	-7086.0
RGS8	-7040.0
CCR9	-7000.0
GNA14	-6980.0
RBP1	-6975.0
AVPR2	-6968.0
ARHGEF17	-6885.0
ADCY6	-6882.0
PTGER2	-6876.0
OR51E1	-6846.0
GPR39	-6779.0
CNR2	-6771.0
ADCY4	-6759.0
APOA4	-6758.0
ARRB2	-6754.0
ECE1	-6749.0
CCL19	-6713.0
PRKACB	-6707.0
PSAP	-6675.0
ARHGEF10L	-6624.0
HSD17B6	-6589.0
S1PR4	-6587.0
TSHR	-6499.0
HTR7	-6482.0
CXCR5	-6476.0
ADCY2	-6434.0
TRIO	-6348.0
SSTR1	-6304.0
C3	-6303.0
CHRM4	-6286.0
GPR132	-6259.0
PPP2CA	-6258.0
PIK3R6	-6249.0
REEP6	-6204.0
FGD4	-6196.0
TAC3	-6187.0
WNT6	-6186.0
RDH8	-6074.0
RAMP2	-6073.0
FZD3	-6063.0
TACR1	-6047.0
ITPR3	-6046.0
PTGDR2	-6038.0
OR52I1	-6033.5
OR52I2	-6033.5
PCP2	-6000.0
FGD1	-5982.0
TACR3	-5973.0
OR6S1	-5969.0
AKT2	-5958.0
GNG12	-5884.0
PPP1CA	-5881.0
WNT2B	-5857.0
ITPR2	-5837.0
SUCNR1	-5782.0
KEL	-5755.0
WNT8B	-5701.0
RAMP1	-5656.0
P2RY6	-5637.0
AGTR1	-5580.0
PTH1R	-5552.0
ARHGEF19	-5545.0
LRP2	-5544.0
TACR2	-5487.0
PIK3R5	-5482.0
PDE7B	-5405.0
OR6K6	-5329.0
TSHB	-5315.0
ARHGEF6	-5311.0
GNAT2	-5270.0
RLBP1	-5232.0
PTGER1	-5226.0
CXCR4	-5218.0
AKAP13	-5190.0
WNT16	-5176.0
PRKCH	-5149.5
GNAO1	-5147.0
OR6N2	-5135.0
CCL22	-5101.0
RCVRN	-5100.0
SSTR4	-5037.0
NMUR1	-5014.0
NET1	-4984.0
PRKAR1A	-4970.0
P2RY10	-4936.0
NGEF	-4851.0
CXCL9	-4847.0
ADGRE5	-4844.0
GAL	-4837.0
CRHBP	-4802.0
APLNR	-4782.0
NPW	-4751.0
GRM5	-4699.0
PDE4A	-4632.0
TAS2R60	-4610.0
GNB4	-4593.0
XCR1	-4583.0
ARHGEF38	-4562.0
PDE6A	-4543.0
FNTB	-4523.5
RGS3	-4491.0
FPR2	-4479.5
FPR3	-4479.5
CCR6	-4453.0
LRAT	-4448.0
DHRS3	-4431.0
GNAI2	-4425.0
MC5R	-4388.0
ADRA1D	-4383.0
PDPK1	-4325.0
PTCH2	-4298.0
PROKR2	-4225.0
DGKH	-4197.0
GPR4	-4192.0
GRPR	-4160.0
TAS2R3	-4153.0
HTR1F	-4088.0
NMT2	-4070.0
BDKRB2	-4057.0
PLCB1	-4053.0
ADCY1	-4044.0
LPAR6	-4022.0
SSTR3	-3984.0
RHO	-3979.0
GRM8	-3921.0
GHRHR	-3915.0
CAMK2A	-3898.0
GNB1	-3895.0
MCHR1	-3891.0
C3AR1	-3874.0
OR52B2	-3822.0
NPB	-3820.0
UTS2	-3797.0
CCL4	-3785.5
HSPG2	-3764.0
RPS6KA3	-3698.0
CHRM1	-3677.0
WNT9A	-3665.0
PPP2CB	-3632.0
GNRHR	-3625.0
F2	-3616.0
CXCL11	-3606.0
DGKK	-3596.0
GPC2	-3565.0
PTH2	-3564.0
PRKCQ	-3483.0
PPP2R1A	-3477.0
GPR84	-3469.0
RGR	-3467.0
RXFP1	-3454.0
GPIHBP1	-3404.0
ROCK2	-3394.0
CCR3	-3385.0
ACKR4	-3367.0
OR5B2	-3361.0
GRB2	-3336.0
EDN1	-3312.0
PTGIR	-3311.0
LRP10	-3298.0
OR51E2	-3273.0
GPR31	-3246.0
CD55	-3223.0
HTR5A	-3216.0
GPR183	-3193.0
GUCA1B	-3130.0
HEBP1	-3127.0
OR8H1	-3118.0
OR8H2	-3118.0
OR8H3	-3118.0
RHOB	-3080.0
GNG7	-3060.0
PREX1	-3045.0
SDC4	-2987.0
WNT7B	-2916.0
GNA11	-2862.0
SOS1	-2808.0
SSTR5	-2799.0
PRKCG	-2783.0
CCL17	-2763.0
CYP4V2	-2726.0
PPP3CA	-2656.0
ADORA2A	-2639.0
CCL2	-2628.0
CDK5	-2600.0
ARHGEF18	-2547.5
APLN	-2542.0
PPBP	-2477.0
LPL	-2467.0
WNT8A	-2439.0
P2RY2	-2415.0
OR8G1	-2378.5
OR8G5	-2378.5
ADCY5	-2343.0
FZD7	-2287.0
PENK	-2272.0
REEP2	-2261.0
HRAS	-2253.0
CX3CL1	-2245.0
OR10G2	-2217.0
FPR1	-2214.0
LTB4R	-2187.0
RGS1	-2147.0
RLN3	-2119.0
GPC3	-2107.0
KISS1	-2106.0
ADM2	-2081.0
CCKAR	-2081.0
CCR4	-2081.0
GNG13	-2081.0
OPN1LW	-2081.0
OPN1MW	-2081.0
OR7E24	-2063.0
SDC3	-2040.0
NPFF	-2026.0
OR5P2	-2010.0
OR6Y1	-1916.0
OR8K3	-1912.0
PLPPR5	-1872.0
WNT7A	-1849.0
OR2F1	-1842.5
OR2F2	-1842.5
GPR176	-1832.0
F2RL2	-1823.0
OR11A1	-1818.0
ADCY9	-1812.0
OR10K1	-1811.0
PRKCA	-1808.0
GHSR	-1789.0
DAGLA	-1781.0
GPR55	-1771.0
OR5G3	-1752.5
CCKBR	-1743.0
CXCL10	-1631.0
EGFR	-1624.0
CXCL16	-1619.0
OR10V1	-1562.5
OR14J1	-1562.5
OR1I1	-1562.5
OR1Q1	-1562.5
OR4A15	-1562.5
OR4P4	-1562.5
OR56B4	-1562.5
OR5M11	-1562.5
OR5P3	-1562.5
OR5T1	-1562.5
OR5T3	-1562.5
OR6C2	-1562.5
OR6C68	-1562.5
OR8B8	-1562.5
OR5AK2	-1523.0
OR5AK3P	-1523.0
TAS2R14	-1512.0
METAP1	-1481.0
GALR1	-1455.0
NPSR1	-1445.0
WNT3	-1443.0
TRHR	-1407.0
WNT3A	-1406.0
EDNRB	-1365.0
OR4B1	-1361.5
GPC6	-1334.0
PLXNB1	-1301.0
CASR	-1291.0
C5AR1	-1280.0
ARHGEF39	-1272.0
RGS13	-1258.0
CCR7	-1237.0
GRM6	-1224.0
OR10A3	-1219.5
OR10A6	-1219.5
HTR4	-1218.0
GPR45	-1179.0
GPR143	-1156.0
GPR35	-1144.0
CXCL13	-1141.0
AGRN	-1136.0
OR9G1	-1126.0
GPSM2	-1112.0
DRD5	-987.0
MTNR1A	-987.0
OR10J5	-987.0
OR11G2	-987.0
OR12D3	-987.0
OR1A1	-987.0
OR1A2	-987.0
OR1J4	-987.0
OR1P1	-987.0
OR2A1	-987.0
OR2T1	-987.0
OR2W3	-987.0
OR4C16	-987.0
OR4C6	-987.0
OR51G2	-987.0
OR51Q1	-987.0
OR52E4	-987.0
OR5AL1	-987.0
OR5R1	-987.0
OR7G1	-987.0
OR8B12	-987.0
OR8B2	-987.0
OR8B3	-987.0
OR8D4	-987.0
OR9K2	-987.0
PROK1	-987.0
RBP2	-987.0
TAAR5	-987.0
TAS2R1	-987.0
CHRM2	-907.5
OR2B11	-907.5
OR2H1	-907.5
OR2H2	-907.5
OR4D1	-907.5
OR52M1	-907.5
OR2T29	-895.0
OR2T4	-895.0
OR2T5	-895.0
OR5B3	-884.0
OR4C15	-879.0
ARHGEF10	-775.0
PPP3CB	-748.0
CALCR	-738.0
OR14C36	-733.5
OR52N2	-733.5
OR56B2P	-733.5
OR7G2	-733.5
OPRL1	-730.0
OR5AC1	-686.0
RGS4	-680.0
HCRTR1	-648.0
RHOA	-640.0
CCR10	-637.0
RETSAT	-602.0
APOA1	-547.0
OR2AK2	-519.5
OR5H1	-519.5
OR5H14	-519.5
OR5H15	-519.5
OR5H6	-519.5
ARHGEF15	-470.0
PDE6B	-466.0
BRS3	-461.0
ARHGEF33	-451.0
GPHB5	-374.0
FZD9	-370.0
OR52D1	-338.5
NPY5R	-309.0
OR10G3	-309.0
OR4A47	-309.0
OR4F6	-309.0
OR51F2	-309.0
OR52P1P	-309.0
OR9A4	-309.0
CGA	-282.0
DGKD	-273.0
REEP1	-250.0
REEP5	-211.0
CAMKK2	-200.0
CXCL12	-188.0
OPRD1	-187.0
KALRN	-177.0
OR7D4	-133.0
OR5AN1	-121.5
OR1N1	-118.0
RGS18	-112.0
GNB5	-108.0
CALM1	-83.0
OR10AG1	-40.0
GPR37L1	-27.0
ARRB1	-23.0
GPR65	-16.0
REEP3	-8.0
OR6B2	6.5
OR6B3	6.5
OR4F17	11.0
OR4F4	11.0
OR4F5	11.0
AVPR1A	53.0
PIK3CA	85.0
GNA15	89.0
TAS2R4	142.0
CALCB	231.0
CNGA1	231.0
FFAR1	231.0
IAPP	231.0
MC3R	231.0
NPBWR1	231.0
OR10W1	231.0
OR13F1	231.0
OR13J1	231.0
OR1B1	231.0
OR1J1	231.0
OR1M1	231.0
OR2A14	231.0
OR2A5	231.0
OR2AP1	231.0
OR2L13	231.0
OR2Y1	231.0
OR4A16	231.0
OR4C11	231.0
OR4C12	231.0
OR4C3	231.0
OR4D11	231.0
OR4D2	231.0
OR4D6	231.0
OR4F15	231.0
OR4X2	231.0
OR51F1	231.0
OR52E2	231.0
OR52H1	231.0
OR52L1	231.0
OR52R1	231.0
OR56B1	231.0
OR5A1	231.0
OR5B17	231.0
OR5L1	231.0
OR5L2	231.0
OR5M8	231.0
OR6X1	231.0
OR8K5	231.0
OR9Q2	231.0
PTH2R	231.0
RGS21	231.0
RTP1	231.0
TAAR8	231.0
TAS2R7	231.0
LHCGR	340.5
GIP	344.0
OR5C1	346.0
TAS2R42	355.0
NMT1	404.0
OR2B2	420.0
NPY4R	446.5
OXT	449.0
PRLHR	457.0
OR4K15	540.0
OR6C1	540.0
TAS2R19	549.0
TAS2R20	549.0
TAS2R30	549.0
TAS2R31	549.0
TAS2R43	549.0
TAS2R46	549.0
TAS2R50	549.0
OPN4	560.0
OR8A1	563.0
APOB	573.0
ADCYAP1	576.0
PPP2R5D	596.0
PIK3R3	597.5
GNRH1	612.0
F2RL1	616.0
OR5W2	676.0
GPR17	677.0
PPEF1	686.0
GRM3	693.0
OR2AG1	700.0
TAC1	700.0
RGS16	809.0
F2RL3	826.0
OR52E6	842.0
OR52E8	842.0
OR8D1	842.0
FSHR	861.5
OR4M1	861.5
OR4M2	861.5
OR4X1	861.5
OR51B6	861.5
OR51I2	861.5
PYY	861.5
FFAR3	896.0
OR10C1	896.0
OR10S1	896.0
OR2V1	896.0
OR4K5	896.0
OR51A2	896.0
OR51A4	896.0
OR51V1	896.0
OR52K2	896.0
OR2V2	917.5
OR2Z1	917.5
OPN5	921.0
TAS2R13	930.0
NLN	943.0
CCL3	960.0
GNG5	992.0
GHRH	1070.0
OR10H1	1093.5
OR10H5	1093.5
QRFP	1095.0
CAMK4	1172.0
GRM2	1192.0
FFAR4	1193.0
GRK2	1198.0
TAS2R10	1246.0
GNAT3	1292.0
RPS6KA2	1294.0
SSTR2	1311.0
XCL1	1380.5
XCL2	1380.5
OR52E5	1404.0
OR2AG2	1419.5
OR7C2	1419.5
OR8U1	1419.5
TAAR1	1419.5
AKT1	1488.0
OR4N5	1533.0
PRKCD	1551.0
GPR83	1568.0
DRD3	1587.0
ADCY3	1612.0
GRK1	1615.0
ADM	1625.0
GPR15	1643.0
APOM	1657.0
PDE3B	1668.0
OR13C3	1717.0
CRHR1	1747.0
NRAS	1786.0
GUCY2D	1791.0
HRH4	1810.0
PROK2	1822.0
DGKQ	1845.0
GPRC6A	1876.0
PNLIP	1909.0
VAV1	1912.0
GRP	1947.0
CXCL6	1966.0
GALR3	1969.0
SCTR	1986.0
OR6K3	2052.0
FZD4	2057.0
MAPK1	2063.0
LRP8	2101.0
HTR2B	2125.0
OR2T12	2143.0
OR2T33	2143.0
OR2T8	2143.0
DHH	2159.0
RTP4	2164.0
MC2R	2177.0
DRD2	2184.0
ADCY7	2210.0
OR2AT4	2241.0
OR6C70	2316.5
P2RY12	2339.0
OR6C76	2370.0
SCT	2430.0
WNT5A	2473.0
GRK5	2483.0
RGS22	2514.0
MAPK3	2532.0
PRKCB	2630.0
GPR68	2735.0
GPHA2	2779.0
HCRT	2813.0
TBXA2R	2824.0
ADRB2	2844.0
HCAR2	2866.5
HCAR3	2866.5
WNT1	2881.0
CAMKMT	2915.0
LDLR	2957.0
GUCY2F	3001.0
PDE8B	3035.5
CCR1	3082.0
GNA12	3137.0
PDYN	3143.0
CCL23	3192.0
SHH	3214.0
HCAR1	3224.0
POMC	3261.0
AVP	3271.0
GNG3	3307.0
PDE1A	3353.0
F2R	3369.0
LPAR1	3370.0
RGS7	3418.0
GNAT1	3423.0
P2RY4	3493.0
CCRL2	3501.0
SDR9C7	3561.0
BDKRB1	3562.0
ADRB1	3612.0
GRK4	3623.0
GPC1	3640.0
MYO7A	3664.0
NMB	3696.0
GNAI3	3733.0
GNG11	3752.0
HRH1	3792.0
PDE3A	3794.0
PPP1R1B	3853.0
GPR25	3869.0
BCO1	3884.0
ADRA1B	3941.0
OR5I1	4012.0
SLC24A1	4032.0
CCR8	4126.0
ECE2	4133.5
FGD2	4170.0
PDE8A	4181.0
PTAFR	4229.0
CCK	4270.0
RLN2	4323.5
PLPPR2	4371.0
GNGT2	4376.0
RGS9BP	4413.0
RGS10	4447.0
GHRL	4454.0
PPP2R1B	4513.0
NMU	4522.0
FZD8	4573.0
ADRA2A	4582.0
FZD1	4610.0
HBEGF	4618.0
HTR1B	4630.0
DGKA	4645.0
OR51D1	4699.0
CAMKK1	4711.0
MAPK7	4725.0
PLPPR4	4737.0
TRPC7	4748.0
HRH3	4786.0
LRP1	4809.0
CALCA	4836.0
TIAM2	4841.0
CCL27	4856.0
RBP3	4858.0
ADRA2C	4926.0
GPR37	4931.0
ROCK1	4962.0
RDH10	5000.0
FZD6	5042.0
PPP3R1	5058.5
RGS9	5078.0
RAMP3	5107.0
FZD5	5173.0
METAP2	5174.0
HCRTR2	5199.0
RASGRF2	5220.0
RGSL1	5265.0
OXTR	5278.0
GNA13	5282.0
OR6K2	5286.0
GIPR	5394.0
PRKX	5448.5
ADGRE1	5461.0
UTS2B	5468.0
PDE10A	5495.0
RHOC	5509.5
FFAR2	5519.0
NMBR	5522.0
AVPR1B	5580.0
S1PR5	5597.0
UCN	5600.0
DRD4	5612.0
S1PR2	5627.0
HTR2A	5650.0
PTCH1	5659.0
RGS19	5668.0
CMKLR1	5729.0
GPR18	5762.0
OR1F1	5776.0
VAV2	5813.0
KRAS	5849.0
PMCH	5889.0
ARHGEF25	5966.5
PTGDR	6020.0
FZD2	6035.0
BCO2	6058.0
ARHGEF12	6104.0
TAS2R41	6144.0
NAPEPLD	6226.0
GNAZ	6253.0
FGD3	6255.0
GNB2	6264.0
OR6N1	6265.0
ACKR3	6294.0
CRH	6329.0
VIPR2	6379.0
RDH12	6399.0
C5AR2	6406.0
OR2K2	6446.0
SDC2	6449.0
REEP4	6463.0
GRM1	6498.0
STRA6	6510.0
RDH5	6515.0
OR4E1	6518.0
ADRA1A	6572.0
GNG8	6614.0
RGS12	6733.0
KISS1R	6746.0
GNG2	6793.0
TAS1R1	6812.0
ADCY8	6825.0
PIK3CG	6844.0
OPRK1	6857.0
WNT2	6877.0
PTGFR	6884.0
GPSM1	6904.0
TIAM1	6942.0
P2RY1	6949.0
LTB4R2	6967.0
RASGRP1	7000.0
LPAR4	7063.0
GUCA1A	7066.0
RPE65	7074.0
GNG10	7112.0
S1PR3	7127.0
ANXA1	7137.0
GABBR2	7146.0
NMUR2	7148.0
CCL21	7185.0
ADCYAP1R1	7189.0
PLCB2	7190.0
LPAR3	7241.0
PDE4B	7268.0
ABCA4	7305.0
SDC1	7316.0
DHRS9	7322.0
GRM7	7349.0
ECT2	7350.0
DGKI	7390.0
GPBAR1	7429.0
CAMK2G	7477.0
APP	7480.0
FNTA	7484.0
AGTR2	7492.0
EDN2	7506.0
MMP3	7551.0
BTK	7564.0
ACKR2	7589.0
CCR5	7623.0
ARHGEF3	7632.0
P2RY13	7646.0
SOS2	7658.0
LRP12	7671.0
AHCYL1	7728.0
WNT11	7757.0
CX3CR1	7784.0
HTR1A	7853.5
HTR1D	7853.5
WNT10B	7877.0
GPER1	7908.0
GNB3	7932.0
PNOC	7937.0
CALCRL	7971.0
ARHGEF2	7980.0
DRD1	8013.0
SMO	8017.0
CYSLTR1	8025.0
PRKAR1B	8032.0
UCN2	8033.0
AWAT2	8046.0
PIK3R1	8109.0
OPN1SW	8117.0
ADORA3	8119.0
HSD17B1	8140.0
NTSR2	8169.0
CCL7	8170.0
KPNA2	8174.0
HRH2	8194.0
TRPC6	8208.0
MC4R	8265.0
PDE6G	8266.0
ARHGEF26	8302.0
ABHD6	8329.0
CNGB1	8343.0
LPAR2	8362.0
OPN3	8414.0
CREB1	8434.0
PLA2G4A	8549.0
GLP1R	8565.0
WNT9B	8579.0
RDH11	8604.5
AKT3	8609.0
TRPC3	8707.0
OPRM1	8749.0
PDE7A	8851.0
ITPR1	8900.0

---

Cytosolic tRNA aminoacylation

Cytosolic tRNA aminoacylation

	245
set	Cytosolic tRNA aminoacylation
setSize	23
pANOVA	0.00226
s.dist	0.368
p.adjustANOVA	0.0697

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NARS1	8198.0
EPRS1	7828.0
TARS1	7731.0
GARS1	7641.0
IARS1	7272.0
PPA1	7256.0
WARS1	6861.0
HARS1	6860.0
AIMP1	6191.0
EEF1E1	5978.5
CARS1	4806.0
MARS1	4257.0
DARS1	3988.0
AIMP2	3169.0
FARSA	1906.0
YARS1	1102.0
LARS1	795.0
KARS1	648.0
RARS1	-424.0
FARSB	-1497.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NARS1	8198.0
EPRS1	7828.0
TARS1	7731.0
GARS1	7641.0
IARS1	7272.0
PPA1	7256.0
WARS1	6861.0
HARS1	6860.0
AIMP1	6191.0
EEF1E1	5978.5
CARS1	4806.0
MARS1	4257.0
DARS1	3988.0
AIMP2	3169.0
FARSA	1906.0
YARS1	1102.0
LARS1	795.0
KARS1	648.0
RARS1	-424.0
FARSB	-1497.0
VARS1	-5052.0
AARS1	-5067.0
SARS1	-5612.0

---

p130Cas linkage to MAPK signaling for integrins

p130Cas linkage to MAPK signaling for integrins

	1427
set	p130Cas linkage to MAPK signaling for integrins
setSize	15
pANOVA	0.00231
s.dist	-0.454
p.adjustANOVA	0.0697

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGB	-9053.0
FGA	-8696.0
PTK2	-8355.0
SRC	-8095.0
FGG	-8035.0
BCAR1	-7614.0
VWF	-7285.0
ITGA2B	-7222.0
TLN1	-5122.0
APBB1IP	-3673.0
ITGB3	-3380.5
RAP1A	937.0
CRK	2198.0
RAP1B	4145.0
FN1	6913.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGB	-9053.0
FGA	-8696.0
PTK2	-8355.0
SRC	-8095.0
FGG	-8035.0
BCAR1	-7614.0
VWF	-7285.0
ITGA2B	-7222.0
TLN1	-5122.0
APBB1IP	-3673.0
ITGB3	-3380.5
RAP1A	937.0
CRK	2198.0
RAP1B	4145.0
FN1	6913.0

---

NRAGE signals death through JNK

NRAGE signals death through JNK

	753
set	NRAGE signals death through JNK
setSize	56
pANOVA	0.00238
s.dist	-0.235
p.adjustANOVA	0.0704

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ARHGEF37	-8834
ARHGEF1	-8718
OBSCN	-8574
ARHGEF7	-8534
PLEKHG5	-8454
ITSN1	-8377
MAGED1	-8312
ARHGEF11	-8287
NGFR	-8192
ARHGEF40	-7699
MCF2	-7686
ARHGEF16	-7667
ABR	-7655
MCF2L	-7517
ARHGEF5	-7293
PLEKHG2	-7206
VAV3	-7088
ARHGEF17	-6885
ARHGEF10L	-6624
TRIO	-6348

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ARHGEF37	-8834.0
ARHGEF1	-8718.0
OBSCN	-8574.0
ARHGEF7	-8534.0
PLEKHG5	-8454.0
ITSN1	-8377.0
MAGED1	-8312.0
ARHGEF11	-8287.0
NGFR	-8192.0
ARHGEF40	-7699.0
MCF2	-7686.0
ARHGEF16	-7667.0
ABR	-7655.0
MCF2L	-7517.0
ARHGEF5	-7293.0
PLEKHG2	-7206.0
VAV3	-7088.0
ARHGEF17	-6885.0
ARHGEF10L	-6624.0
TRIO	-6348.0
BCL2L11	-6346.0
FGD4	-6196.0
FGD1	-5982.0
ARHGEF19	-5545.0
ARHGEF6	-5311.0
AKAP13	-5190.0
NET1	-4984.0
NGEF	-4851.0
ARHGEF38	-4562.0
PREX1	-3045.0
SOS1	-2808.0
ARHGEF18	-2547.5
AATF	-2176.0
ARHGEF39	-1272.0
ARHGEF10	-775.0
ARHGEF15	-470.0
ARHGEF33	-451.0
KALRN	-177.0
BAD	928.0
VAV1	1912.0
RAC1	2240.0
NGF	2470.0
FGD2	4170.0
TIAM2	4841.0
RASGRF2	5220.0
GNA13	5282.0
VAV2	5813.0
MAPK8	5956.0
ARHGEF12	6104.0
FGD3	6255.0
TIAM1	6942.0
ECT2	7350.0
ARHGEF3	7632.0
SOS2	7658.0
ARHGEF2	7980.0
ARHGEF26	8302.0

---

Influenza Infection

Influenza Infection

	563
set	Influenza Infection
setSize	128
pANOVA	0.00253
s.dist	0.155
p.adjustANOVA	0.0725

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL13A	8957
RPL3	8943
RPS15A	8920
RPL29	8919
RPS16	8907
RPL6	8889
NUP58	8776
NUP37	8600
CLTA	8586
POLR2G	8271
KPNA2	8174
RPL37	8039
POLR2H	7476
DNAJC3	7406
RPL30	7370
RPS27A	7369
RPL7A	7100
RPS23	7033
RANBP2	6945
EIF2AK2	6933

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL13A	8957.0
RPL3	8943.0
RPS15A	8920.0
RPL29	8919.0
RPS16	8907.0
RPL6	8889.0
NUP58	8776.0
NUP37	8600.0
CLTA	8586.0
POLR2G	8271.0
KPNA2	8174.0
RPL37	8039.0
POLR2H	7476.0
DNAJC3	7406.0
RPL30	7370.0
RPS27A	7369.0
RPL7A	7100.0
RPS23	7033.0
RANBP2	6945.0
EIF2AK2	6933.0
NUP153	6854.0
PABPN1	6598.5
NUP98	6576.0
RPS18	6557.0
RPLP2	6538.0
RPL10L	6517.0
KPNA5	6286.0
RPS15	6242.0
NDC1	6233.0
RPS5	6228.0
RPL22	5939.0
XPO1	5929.0
NUP160	5904.0
RPS14	5784.0
GRSF1	5690.0
RPL31	5673.0
CALR	5643.0
NUP93	5363.0
RPS26	5195.0
RPL9	4882.0
RPS3A	4794.0
KPNA7	4735.0
NUP155	4673.0
CLTC	4525.0
RPL19	4494.0
KPNA4	4361.0
RPL5	4255.0
RPS21	4017.0
RPS13	3688.0
POLR2D	3487.0
POLR2I	3477.0
RPS8	3383.0
NUP50	3293.0
RPS28	3175.0
RPL7	3151.0
NUP188	3150.0
RPL27	2912.0
RPL18	2790.0
RPS3	2715.0
NUP54	2641.0
NUP35	2557.0
RPS4X	2555.0
NUP88	2333.0
RPS11	2321.0
POLR2B	2214.0
RPS19	2111.0
CPSF4	2107.0
RPL37A	2071.0
ISG15	1321.0
RPL36	1297.0
KPNB1	1280.0
SEC13	1065.0
NUP107	935.0
RPL10A	667.0
RPL11	231.0
RPL21	231.0
NUP42	-38.0
TPR	-207.0
RPS25	-242.0
AAAS	-496.0
RPLP1	-660.0
RAN	-987.0
TGFB1	-1162.0
RPSA	-1493.0
RPS2	-1703.0
POLR2F	-1805.0
RPS17	-1958.0
RPS10	-1984.5
RPL23	-2023.0
RPL18A	-2151.0
RPS7	-2157.0
UBA52	-2166.0
KPNA3	-2304.0
KPNA1	-2755.0
RPS27L	-3093.0
NUP62	-3094.0
GTF2F1	-3198.0
RPL35	-3206.0
GTF2F2	-3213.0
NUP205	-3219.0
RPL24	-3268.0
RPL28	-3293.0
POM121	-3732.5
POM121C	-3732.5
NUP133	-4126.0
RPL8	-4167.0
CANX	-4217.0
IPO5	-4272.0
NUP210	-4336.0
RAE1	-4461.0
POLR2C	-4917.0
HSPA1A	-4959.5
RPL38	-5629.0
RPS6	-5720.0
POLR2A	-5792.0
RPL15	-6128.0
RPL23A	-6843.0
POLR2L	-6941.0
RPL3L	-7058.0
PARP1	-7161.0
RPL13	-7209.0
RPS9	-7535.0
NUP85	-8017.0
NUP43	-8128.0
POLR2E	-8423.0
FAU	-8625.0
NUP214	-8732.0
RPL35A	-8900.0

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.0.3 (2020-10-10)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 18.04.5 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.7.1
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.7.1
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.1.0               GGally_2.0.0               
##  [3] ggplot2_3.3.2               beeswarm_0.2.3             
##  [5] gtools_3.8.2                tibble_3.0.4               
##  [7] dplyr_1.0.2                 echarts4r_0.3.3            
##  [9] gplots_3.1.0                mitch_1.2.2                
## [11] DESeq2_1.30.0               SummarizedExperiment_1.20.0
## [13] Biobase_2.50.0              MatrixGenerics_1.2.0       
## [15] matrixStats_0.57.0          GenomicRanges_1.42.0       
## [17] GenomeInfoDb_1.26.0         IRanges_2.24.0             
## [19] S4Vectors_0.28.0            BiocGenerics_0.36.0        
## [21] reshape2_1.4.4             
## 
## loaded via a namespace (and not attached):
##  [1] httr_1.4.2             jsonlite_1.7.1         bit64_4.0.5           
##  [4] splines_4.0.3          assertthat_0.2.1       shiny_1.5.0           
##  [7] highr_0.8              blob_1.2.1             GenomeInfoDbData_1.2.4
## [10] yaml_2.2.1             backports_1.2.0        pillar_1.4.6          
## [13] RSQLite_2.2.1          lattice_0.20-41        glue_1.4.2            
## [16] digest_0.6.27          RColorBrewer_1.1-2     promises_1.1.1        
## [19] XVector_0.30.0         colorspace_2.0-0       htmltools_0.5.0       
## [22] httpuv_1.5.4           Matrix_1.2-18          plyr_1.8.6            
## [25] XML_3.99-0.5           pkgconfig_2.0.3        genefilter_1.72.0     
## [28] zlibbioc_1.36.0        purrr_0.3.4            xtable_1.8-4          
## [31] scales_1.1.1           later_1.1.0.1          BiocParallel_1.24.1   
## [34] annotate_1.68.0        generics_0.1.0         ellipsis_0.3.1        
## [37] withr_2.3.0            survival_3.2-7         magrittr_1.5          
## [40] crayon_1.3.4           mime_0.9               evaluate_0.14         
## [43] memoise_1.1.0          MASS_7.3-53            tools_4.0.3           
## [46] lifecycle_0.2.0        stringr_1.4.0          munsell_0.5.0         
## [49] locfit_1.5-9.4         DelayedArray_0.16.0    AnnotationDbi_1.52.0  
## [52] compiler_4.0.3         caTools_1.18.0         rlang_0.4.8           
## [55] grid_4.0.3             RCurl_1.98-1.2         htmlwidgets_1.5.2     
## [58] rmarkdown_2.5          bitops_1.0-6           testthat_3.0.0        
## [61] gtable_0.3.0           DBI_1.1.0              reshape_0.8.8         
## [64] R6_2.5.0               gridExtra_2.3          knitr_1.30            
## [67] fastmap_1.0.1          bit_4.0.4              rprojroot_1.3-2       
## [70] desc_1.2.0             KernSmooth_2.23-18     stringi_1.5.3         
## [73] Rcpp_1.0.5             vctrs_0.3.4            geneplotter_1.68.0    
## [76] tidyselect_1.1.0       xfun_0.19

END of report