Mitch Report

date generated: 2025-05-12

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch

	x
HBB	3.758520
HBA2	3.496189
HBA1	3.151622
TMEM131	2.768819
YES1	2.738207
CYBB	-2.459079

Here are some metrics about the input data profile:

Profiling data metrics

	Profile metrics
num_genesets	9216
num_genes_in_profile	1874
duplicated_genes_present	0
num_profile_genes_in_sets	1821
num_profile_genes_not_in_sets	53

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets:

Gene set metrics

	Gene sets metrics
num_genesets	9216
num_genesets_excluded	8471
num_genesets_included	745

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

set	setSize	pANOVA	s.dist	p.adjustANOVA
GO:0007492 endoderm development	5	0.002770	0.773	0.295
GO:0031624 ubiquitin conjugating enzyme binding	6	0.004310	0.674	0.367
GO:1901526 positive regulation of mitophagy	5	0.011200	0.655	0.491
GO:0042162 telomeric DNA binding	7	0.002780	0.654	0.295
GO:0015026 coreceptor activity	5	0.014800	0.630	0.554
GO:0000123 histone acetyltransferase complex	5	0.016300	0.621	0.554
GO:0033962 P-body assembly	5	0.017300	0.615	0.554
GO:0009966 regulation of signal transduction	10	0.000816	0.612	0.174
GO:0071363 cellular response to growth factor stimulus	7	0.005940	-0.601	0.411
GO:1902430 negative regulation of amyloid-beta formation	5	0.022600	0.590	0.594
GO:1990869 cellular response to chemokine	7	0.008880	0.572	0.449
GO:0030071 regulation of mitotic metaphase/anaphase transition	7	0.009230	0.569	0.449
GO:0070316 regulation of G0 to G1 transition	7	0.009230	0.569	0.449
GO:2000819 regulation of nucleotide-excision repair	7	0.009230	0.569	0.449
GO:0071300 cellular response to retinoic acid	7	0.009500	0.567	0.449
GO:0031491 nucleosome binding	6	0.016500	0.566	0.554
GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity	5	0.031300	0.557	0.594
GO:0050321 tau-protein kinase activity	8	0.006600	0.555	0.411
GO:0060612 adipose tissue development	5	0.034100	0.548	0.623
GO:0048010 vascular endothelial growth factor receptor signaling pathway	6	0.022900	0.537	0.594
GO:0030414 peptidase inhibitor activity	6	0.024500	-0.531	0.594
GO:1902894 negative regulation of miRNA transcription	7	0.015300	0.530	0.554
GO:0004857 enzyme inhibitor activity	7	0.015500	0.529	0.554
GO:0048147 negative regulation of fibroblast proliferation	6	0.025400	-0.528	0.594
GO:2000781 positive regulation of double-strand break repair	8	0.009890	0.528	0.455
GO:1902459 positive regulation of stem cell population maintenance	9	0.006260	0.527	0.411
GO:1902455 negative regulation of stem cell population maintenance	5	0.042000	0.526	0.650
GO:0001046 core promoter sequence-specific DNA binding	6	0.026400	0.524	0.594
GO:0035060 brahma complex	5	0.043600	0.522	0.650
GO:0071564 npBAF complex	5	0.043600	0.522	0.650
GO:0071565 nBAF complex	5	0.043600	0.522	0.650
GO:0099170 postsynaptic modulation of chemical synaptic transmission	6	0.028500	-0.517	0.594
GO:0070507 regulation of microtubule cytoskeleton organization	7	0.018000	0.517	0.558
GO:0050811 GABA receptor binding	5	0.051400	-0.504	0.667
GO:0045596 negative regulation of cell differentiation	7	0.023500	0.495	0.594
GO:0000421 autophagosome membrane	13	0.002250	-0.491	0.294
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production	5	0.062100	-0.483	0.706
GO:0042129 regulation of T cell proliferation	8	0.018600	-0.481	0.566
GO:0001664 G protein-coupled receptor binding	14	0.001930	0.480	0.294
GO:0006622 protein targeting to lysosome	6	0.043700	0.476	0.650
GO:0031589 cell-substrate adhesion	5	0.065700	0.476	0.708
GO:0045953 negative regulation of natural killer cell mediated cytotoxicity	5	0.065700	0.476	0.708
GO:0051893 regulation of focal adhesion assembly	8	0.020500	0.474	0.594
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway	8	0.020700	0.473	0.594
GO:0030971 receptor tyrosine kinase binding	6	0.047400	-0.468	0.667
GO:0035580 specific granule lumen	11	0.007630	-0.466	0.433
GO:0031643 positive regulation of myelination	6	0.050300	-0.462	0.667
GO:1901798 positive regulation of signal transduction by p53 class mediator	5	0.074600	-0.461	0.743
GO:0034142 toll-like receptor 4 signaling pathway	7	0.035100	0.461	0.626
GO:0014044 Schwann cell development	5	0.075700	0.459	0.743

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
GO:0007492 endoderm development	5	2.77e-03	0.773000	0.295000
GO:0031624 ubiquitin conjugating enzyme binding	6	4.31e-03	0.674000	0.367000
GO:1901526 positive regulation of mitophagy	5	1.12e-02	0.655000	0.491000
GO:0042162 telomeric DNA binding	7	2.78e-03	0.654000	0.295000
GO:0015026 coreceptor activity	5	1.48e-02	0.630000	0.554000
GO:0000123 histone acetyltransferase complex	5	1.63e-02	0.621000	0.554000
GO:0033962 P-body assembly	5	1.73e-02	0.615000	0.554000
GO:0009966 regulation of signal transduction	10	8.16e-04	0.612000	0.174000
GO:0071363 cellular response to growth factor stimulus	7	5.94e-03	-0.601000	0.411000
GO:1902430 negative regulation of amyloid-beta formation	5	2.26e-02	0.590000	0.594000
GO:1990869 cellular response to chemokine	7	8.88e-03	0.572000	0.449000
GO:0030071 regulation of mitotic metaphase/anaphase transition	7	9.23e-03	0.569000	0.449000
GO:0070316 regulation of G0 to G1 transition	7	9.23e-03	0.569000	0.449000
GO:2000819 regulation of nucleotide-excision repair	7	9.23e-03	0.569000	0.449000
GO:0071300 cellular response to retinoic acid	7	9.50e-03	0.567000	0.449000
GO:0031491 nucleosome binding	6	1.65e-02	0.566000	0.554000
GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity	5	3.13e-02	0.557000	0.594000
GO:0050321 tau-protein kinase activity	8	6.60e-03	0.555000	0.411000
GO:0060612 adipose tissue development	5	3.41e-02	0.548000	0.623000
GO:0048010 vascular endothelial growth factor receptor signaling pathway	6	2.29e-02	0.537000	0.594000
GO:0030414 peptidase inhibitor activity	6	2.45e-02	-0.531000	0.594000
GO:1902894 negative regulation of miRNA transcription	7	1.53e-02	0.530000	0.554000
GO:0004857 enzyme inhibitor activity	7	1.55e-02	0.529000	0.554000
GO:0048147 negative regulation of fibroblast proliferation	6	2.54e-02	-0.528000	0.594000
GO:2000781 positive regulation of double-strand break repair	8	9.89e-03	0.528000	0.455000
GO:1902459 positive regulation of stem cell population maintenance	9	6.26e-03	0.527000	0.411000
GO:1902455 negative regulation of stem cell population maintenance	5	4.20e-02	0.526000	0.650000
GO:0001046 core promoter sequence-specific DNA binding	6	2.64e-02	0.524000	0.594000
GO:0035060 brahma complex	5	4.36e-02	0.522000	0.650000
GO:0071564 npBAF complex	5	4.36e-02	0.522000	0.650000
GO:0071565 nBAF complex	5	4.36e-02	0.522000	0.650000
GO:0099170 postsynaptic modulation of chemical synaptic transmission	6	2.85e-02	-0.517000	0.594000
GO:0070507 regulation of microtubule cytoskeleton organization	7	1.80e-02	0.517000	0.558000
GO:0050811 GABA receptor binding	5	5.14e-02	-0.504000	0.667000
GO:0045596 negative regulation of cell differentiation	7	2.35e-02	0.495000	0.594000
GO:0000421 autophagosome membrane	13	2.25e-03	-0.491000	0.294000
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production	5	6.21e-02	-0.483000	0.706000
GO:0042129 regulation of T cell proliferation	8	1.86e-02	-0.481000	0.566000
GO:0001664 G protein-coupled receptor binding	14	1.93e-03	0.480000	0.294000
GO:0006622 protein targeting to lysosome	6	4.37e-02	0.476000	0.650000
GO:0031589 cell-substrate adhesion	5	6.57e-02	0.476000	0.708000
GO:0045953 negative regulation of natural killer cell mediated cytotoxicity	5	6.57e-02	0.476000	0.708000
GO:0051893 regulation of focal adhesion assembly	8	2.05e-02	0.474000	0.594000
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway	8	2.07e-02	0.473000	0.594000
GO:0030971 receptor tyrosine kinase binding	6	4.74e-02	-0.468000	0.667000
GO:0035580 specific granule lumen	11	7.63e-03	-0.466000	0.433000
GO:0031643 positive regulation of myelination	6	5.03e-02	-0.462000	0.667000
GO:1901798 positive regulation of signal transduction by p53 class mediator	5	7.46e-02	-0.461000	0.743000
GO:0034142 toll-like receptor 4 signaling pathway	7	3.51e-02	0.461000	0.626000
GO:0014044 Schwann cell development	5	7.57e-02	0.459000	0.743000
GO:0019216 regulation of lipid metabolic process	6	5.17e-02	0.459000	0.667000
GO:1900076 regulation of cellular response to insulin stimulus	5	7.58e-02	0.459000	0.743000
GO:0045744 negative regulation of G protein-coupled receptor signaling pathway	5	7.79e-02	-0.456000	0.743000
GO:0050687 negative regulation of defense response to virus	5	7.79e-02	0.456000	0.743000
GO:0014823 response to activity	6	5.37e-02	-0.456000	0.667000
GO:0048156 tau protein binding	14	3.34e-03	0.454000	0.299000
GO:0035987 endodermal cell differentiation	6	5.44e-02	0.454000	0.667000
GO:0032024 positive regulation of insulin secretion	7	3.80e-02	-0.454000	0.634000
GO:1990948 ubiquitin ligase inhibitor activity	7	3.86e-02	-0.452000	0.638000
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway	7	3.91e-02	-0.451000	0.639000
GO:0046597 negative regulation of viral entry into host cell	6	5.69e-02	-0.450000	0.677000
GO:0006995 cellular response to nitrogen starvation	5	8.41e-02	-0.447000	0.767000
GO:0098693 regulation of synaptic vesicle cycle	5	8.45e-02	-0.446000	0.767000
GO:1904115 axon cytoplasm	8	3.03e-02	0.443000	0.594000
GO:0050786 RAGE receptor binding	7	4.30e-02	-0.442000	0.650000
GO:0006509 membrane protein ectodomain proteolysis	5	8.77e-02	0.442000	0.767000
GO:0009306 protein secretion	6	6.37e-02	0.438000	0.706000
GO:0071481 cellular response to X-ray	5	9.05e-02	0.438000	0.767000
GO:0045182 translation regulator activity	7	4.54e-02	-0.437000	0.655000
GO:0018107 peptidyl-threonine phosphorylation	13	6.51e-03	0.437000	0.411000
GO:0042554 superoxide anion generation	6	6.50e-02	-0.436000	0.708000
GO:0030509 BMP signaling pathway	9	2.48e-02	0.433000	0.594000
GO:0002548 monocyte chemotaxis	7	4.77e-02	-0.433000	0.667000
GO:0045669 positive regulation of osteoblast differentiation	8	3.55e-02	-0.430000	0.626000
GO:0006334 nucleosome assembly	16	2.99e-03	0.430000	0.299000
GO:0005929 cilium	8	3.56e-02	0.430000	0.626000
GO:0030659 cytoplasmic vesicle membrane	16	3.26e-03	-0.426000	0.299000
GO:1902017 regulation of cilium assembly	8	3.74e-02	-0.426000	0.634000
GO:0006906 vesicle fusion	5	1.00e-01	0.425000	0.767000
GO:0034097 response to cytokine	8	3.77e-02	-0.425000	0.634000
GO:0031683 G-protein beta/gamma-subunit complex binding	6	7.23e-02	0.424000	0.742000
GO:0004521 RNA endonuclease activity	7	5.31e-02	-0.423000	0.667000
GO:0006110 regulation of glycolytic process	5	1.02e-01	0.423000	0.767000
GO:0022625 cytosolic large ribosomal subunit	48	5.32e-07	-0.422000	0.000302
GO:0004177 aminopeptidase activity	5	1.03e-01	-0.422000	0.767000
GO:0009055 electron transfer activity	7	5.41e-02	-0.421000	0.667000
GO:0001892 embryonic placenta development	5	1.04e-01	0.420000	0.767000
GO:0097401 synaptic vesicle lumen acidification	5	1.05e-01	-0.419000	0.767000
GO:0050900 leukocyte migration	9	3.03e-02	0.418000	0.594000
GO:0097435 supramolecular fiber organization	6	7.69e-02	-0.418000	0.743000
GO:0004709 MAP kinase kinase kinase activity	5	1.09e-01	-0.415000	0.767000
GO:0005604 basement membrane	5	1.11e-01	-0.413000	0.767000
GO:0097720 calcineurin-mediated signaling	5	1.13e-01	0.410000	0.767000
GO:0043537 negative regulation of blood vessel endothelial cell migration	5	1.13e-01	-0.410000	0.767000
GO:0030155 regulation of cell adhesion	12	1.42e-02	0.410000	0.554000
GO:0017080 sodium channel regulator activity	5	1.16e-01	-0.406000	0.767000
GO:0043330 response to exogenous dsRNA	6	8.67e-02	0.405000	0.767000
GO:0005834 heterotrimeric G-protein complex	9	3.68e-02	0.403000	0.633000
GO:0043403 skeletal muscle tissue regeneration	5	1.21e-01	-0.401000	0.767000
GO:0000993 RNA polymerase II complex binding	8	5.02e-02	0.401000	0.667000
GO:0043687 post-translational protein modification	7	6.77e-02	-0.399000	0.711000
GO:0031623 receptor internalization	19	2.73e-03	0.399000	0.295000
GO:0034067 protein localization to Golgi apparatus	5	1.24e-01	0.398000	0.767000
GO:0000151 ubiquitin ligase complex	16	6.03e-03	0.398000	0.411000
GO:0004864 protein phosphatase inhibitor activity	6	9.31e-02	-0.397000	0.767000
GO:0042169 SH2 domain binding	10	3.09e-02	-0.395000	0.594000
GO:0043406 positive regulation of MAP kinase activity	6	9.84e-02	-0.390000	0.767000
GO:0048246 macrophage chemotaxis	5	1.35e-01	-0.387000	0.767000
GO:0051894 positive regulation of focal adhesion assembly	7	7.83e-02	0.385000	0.743000
GO:0097009 energy homeostasis	6	1.04e-01	-0.384000	0.767000
GO:0001568 blood vessel development	7	7.91e-02	-0.384000	0.743000
GO:0030855 epithelial cell differentiation	10	3.68e-02	-0.382000	0.633000
GO:0050829 defense response to Gram-negative bacterium	11	2.87e-02	-0.382000	0.594000
GO:0045505 dynein intermediate chain binding	6	1.07e-01	0.381000	0.767000
GO:0060396 growth hormone receptor signaling pathway	5	1.45e-01	-0.377000	0.767000
GO:0016460 myosin II complex	5	1.46e-01	0.376000	0.767000
GO:0001890 placenta development	5	1.47e-01	0.375000	0.767000
GO:0072542 protein phosphatase activator activity	8	6.74e-02	0.374000	0.711000
GO:0120163 negative regulation of cold-induced thermogenesis	7	8.75e-02	-0.374000	0.767000
GO:0070534 protein K63-linked ubiquitination	14	1.62e-02	0.372000	0.554000
GO:0048536 spleen development	5	1.50e-01	-0.372000	0.767000
GO:0031507 heterochromatin formation	8	6.94e-02	-0.372000	0.725000
GO:0034341 response to type II interferon	9	5.45e-02	-0.371000	0.667000
GO:0042100 B cell proliferation	6	1.16e-01	-0.371000	0.767000
GO:0043149 stress fiber assembly	9	5.51e-02	0.370000	0.669000
GO:0046875 ephrin receptor binding	5	1.52e-01	0.370000	0.767000
GO:0032733 positive regulation of interleukin-10 production	10	4.33e-02	-0.370000	0.650000
GO:0009409 response to cold	5	1.53e-01	-0.370000	0.767000
GO:0061158 3’-UTR-mediated mRNA destabilization	7	9.15e-02	0.369000	0.767000
GO:0070182 DNA polymerase binding	6	1.18e-01	0.369000	0.767000
GO:0002502 peptide antigen assembly with MHC class I protein complex	5	1.55e-01	-0.368000	0.767000
GO:0042824 MHC class I peptide loading complex	5	1.55e-01	-0.368000	0.767000
GO:0001836 release of cytochrome c from mitochondria	6	1.20e-01	-0.367000	0.767000
GO:0120009 intermembrane lipid transfer	5	1.58e-01	0.365000	0.767000
GO:0006414 translational elongation	7	9.51e-02	-0.365000	0.767000
GO:0008198 ferrous iron binding	5	1.60e-01	-0.364000	0.767000
GO:0005840 ribosome	36	1.81e-04	-0.363000	0.051300
GO:0010608 post-transcriptional regulation of gene expression	6	1.25e-01	0.362000	0.767000
GO:0002223 stimulatory C-type lectin receptor signaling pathway	9	6.07e-02	0.362000	0.703000
GO:1900034 regulation of cellular response to heat	6	1.25e-01	0.362000	0.767000
GO:0004866 endopeptidase inhibitor activity	6	1.26e-01	-0.362000	0.767000
GO:0106222 lncRNA binding	6	1.27e-01	0.361000	0.767000
GO:0002634 regulation of germinal center formation	5	1.66e-01	-0.358000	0.767000
GO:0150052 regulation of postsynapse assembly	7	1.03e-01	0.357000	0.767000
GO:0008250 oligosaccharyltransferase complex	5	1.68e-01	-0.357000	0.767000
GO:0043388 positive regulation of DNA binding	5	1.68e-01	-0.356000	0.767000
GO:0042752 regulation of circadian rhythm	15	1.74e-02	0.356000	0.554000
GO:0030307 positive regulation of cell growth	14	2.16e-02	-0.356000	0.594000
GO:0060395 SMAD protein signal transduction	5	1.70e-01	0.355000	0.767000
GO:0008180 COP9 signalosome	5	1.70e-01	0.355000	0.767000
GO:0072593 reactive oxygen species metabolic process	5	1.70e-01	0.355000	0.767000
GO:0005484 SNAP receptor activity	6	1.34e-01	0.354000	0.767000
GO:0031201 SNARE complex	6	1.34e-01	0.354000	0.767000
GO:0060324 face development	5	1.73e-01	0.353000	0.767000
GO:0045842 positive regulation of mitotic metaphase/anaphase transition	5	1.74e-01	-0.352000	0.767000
GO:0051085 chaperone cofactor-dependent protein refolding	5	1.74e-01	0.351000	0.767000
GO:0001569 branching involved in blood vessel morphogenesis	5	1.75e-01	-0.351000	0.767000
GO:0005778 peroxisomal membrane	6	1.38e-01	-0.350000	0.767000
GO:0140767 enzyme-substrate adaptor activity	5	1.76e-01	-0.350000	0.767000
GO:1904515 positive regulation of TORC2 signaling	5	1.77e-01	0.349000	0.767000
GO:0070412 R-SMAD binding	6	1.40e-01	0.349000	0.767000
GO:0031047 regulatory ncRNA-mediated gene silencing	6	1.40e-01	0.349000	0.767000
GO:0048388 endosomal lumen acidification	5	1.79e-01	-0.347000	0.767000
GO:0051452 intracellular pH reduction	5	1.79e-01	-0.347000	0.767000
GO:0061795 Golgi lumen acidification	5	1.79e-01	-0.347000	0.767000
GO:0031648 protein destabilization	11	4.69e-02	0.347000	0.667000
GO:0002181 cytoplasmic translation	81	1.13e-07	-0.347000	0.000107
GO:0033176 proton-transporting V-type ATPase complex	6	1.43e-01	-0.346000	0.767000
GO:0002931 response to ischemia	11	4.78e-02	-0.346000	0.667000
GO:0019888 protein phosphatase regulator activity	13	3.17e-02	0.345000	0.594000
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	9	7.41e-02	-0.345000	0.743000
GO:0060100 positive regulation of phagocytosis, engulfment	5	1.83e-01	0.344000	0.767000
GO:0002039 p53 binding	14	2.70e-02	0.343000	0.594000
GO:0043232 intracellular membraneless organelle	5	1.86e-01	-0.342000	0.767000
GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	5	1.88e-01	0.341000	0.767000
GO:0071392 cellular response to estradiol stimulus	5	1.89e-01	0.340000	0.767000
GO:0072562 blood microparticle	21	7.47e-03	0.339000	0.433000
GO:0006936 muscle contraction	9	7.92e-02	0.339000	0.743000
GO:0072583 clathrin-dependent endocytosis	8	9.81e-02	0.338000	0.767000
GO:0070098 chemokine-mediated signaling pathway	5	1.94e-01	-0.336000	0.771000
GO:0043409 negative regulation of MAPK cascade	7	1.25e-01	0.336000	0.767000
GO:0032395 MHC class II receptor activity	5	1.96e-01	-0.335000	0.773000
GO:0017018 myosin phosphatase activity	14	3.14e-02	0.333000	0.594000
GO:0033192 calmodulin-dependent protein phosphatase activity	14	3.14e-02	0.333000	0.594000
GO:0140791 histone H2AXS140 phosphatase activity	14	3.14e-02	0.333000	0.594000
GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	14	3.14e-02	0.333000	0.594000
GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	14	3.14e-02	0.333000	0.594000
GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	14	3.14e-02	0.333000	0.594000
GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	14	3.14e-02	0.333000	0.594000
GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	14	3.14e-02	0.333000	0.594000
GO:1990439 MAP kinase serine/threonine phosphatase activity	14	3.14e-02	0.333000	0.594000
GO:0006402 mRNA catabolic process	7	1.28e-01	-0.333000	0.767000
GO:0060048 cardiac muscle contraction	5	1.99e-01	0.332000	0.777000
GO:2000117 negative regulation of cysteine-type endopeptidase activity	11	5.78e-02	-0.331000	0.683000
GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress	5	2.00e-01	-0.331000	0.777000
GO:0140938 histone H3 methyltransferase activity	6	1.61e-01	0.331000	0.767000
GO:0008429 phosphatidylethanolamine binding	6	1.62e-01	-0.330000	0.767000
GO:0006412 translation	90	1.26e-07	-0.329000	0.000107
GO:0006275 regulation of DNA replication	6	1.66e-01	-0.327000	0.767000
GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process	9	9.06e-02	0.327000	0.767000
GO:0043204 perikaryon	13	4.33e-02	-0.325000	0.650000
GO:0022626 cytosolic ribosome	78	1.10e-06	-0.325000	0.000373
GO:0030101 natural killer cell activation	5	2.10e-01	0.324000	0.787000
GO:0004869 cysteine-type endopeptidase inhibitor activity	6	1.71e-01	-0.324000	0.767000
GO:0070934 CRD-mediated mRNA stabilization	6	1.71e-01	0.323000	0.767000
GO:1900152 negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	6	1.71e-01	0.323000	0.767000
GO:0030878 thyroid gland development	7	1.40e-01	0.323000	0.767000
GO:0098982 GABA-ergic synapse	7	1.41e-01	-0.322000	0.767000
GO:1990782 protein tyrosine kinase binding	9	9.59e-02	0.321000	0.767000
GO:0032467 positive regulation of cytokinesis	6	1.74e-01	0.321000	0.767000
GO:0035725 sodium ion transmembrane transport	8	1.18e-01	0.320000	0.767000
GO:0034236 protein kinase A catalytic subunit binding	5	2.19e-01	0.318000	0.804000
GO:0044754 autolysosome	6	1.80e-01	-0.317000	0.767000
GO:0032153 cell division site	5	2.21e-01	-0.316000	0.808000
GO:0004722 protein serine/threonine phosphatase activity	11	7.04e-02	0.316000	0.731000
GO:0045815 transcription initiation-coupled chromatin remodeling	6	1.82e-01	0.315000	0.767000
GO:0050767 regulation of neurogenesis	6	1.83e-01	-0.315000	0.767000
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway	8	1.24e-01	-0.315000	0.767000
GO:0045109 intermediate filament organization	6	1.83e-01	-0.315000	0.767000
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand	6	1.83e-01	-0.314000	0.767000
GO:0050870 positive regulation of T cell activation	12	6.01e-02	-0.314000	0.701000
GO:0003735 structural constituent of ribosome	86	7.83e-07	-0.314000	0.000333
GO:0097352 autophagosome maturation	7	1.52e-01	-0.313000	0.767000
GO:0048863 stem cell differentiation	5	2.27e-01	0.312000	0.819000
GO:0050729 positive regulation of inflammatory response	27	5.52e-03	-0.310000	0.411000
GO:0006303 double-strand break repair via nonhomologous end joining	9	1.08e-01	0.310000	0.767000
GO:0098641 cadherin binding involved in cell-cell adhesion	6	1.89e-01	-0.310000	0.767000
GO:0071005 U2-type precatalytic spliceosome	7	1.57e-01	-0.310000	0.767000
GO:0032495 response to muramyl dipeptide	5	2.31e-01	0.310000	0.826000
GO:0005154 epidermal growth factor receptor binding	7	1.57e-01	0.310000	0.767000
GO:0002020 protease binding	20	1.75e-02	-0.308000	0.554000
GO:0008307 structural constituent of muscle	5	2.33e-01	0.308000	0.827000
GO:0035023 regulation of Rho protein signal transduction	10	9.25e-02	0.308000	0.767000
GO:0019789 SUMO transferase activity	6	1.93e-01	-0.308000	0.771000
GO:0008340 determination of adult lifespan	5	2.35e-01	0.307000	0.828000
GO:0003746 translation elongation factor activity	6	1.94e-01	-0.307000	0.771000
GO:0045582 positive regulation of T cell differentiation	12	6.65e-02	0.307000	0.711000
GO:0007042 lysosomal lumen acidification	8	1.34e-01	-0.307000	0.767000
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator	5	2.36e-01	-0.307000	0.829000
GO:0003007 heart morphogenesis	6	1.94e-01	0.307000	0.771000
GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation	7	1.62e-01	-0.306000	0.767000
GO:0048208 COPII vesicle coating	5	2.41e-01	0.303000	0.829000
GO:0001786 phosphatidylserine binding	11	8.33e-02	-0.302000	0.767000
GO:0006801 superoxide metabolic process	8	1.41e-01	-0.301000	0.767000
GO:1900182 positive regulation of protein localization to nucleus	7	1.68e-01	0.301000	0.767000
GO:0000045 autophagosome assembly	15	4.43e-02	-0.301000	0.650000
GO:0070161 anchoring junction	9	1.19e-01	0.301000	0.767000
GO:0044297 cell body	13	6.12e-02	0.301000	0.704000
GO:0016514 SWI/SNF complex	7	1.69e-01	0.301000	0.767000
GO:0045740 positive regulation of DNA replication	5	2.48e-01	-0.299000	0.829000
GO:0022604 regulation of cell morphogenesis	5	2.50e-01	-0.298000	0.829000
GO:0070822 Sin3-type complex	5	2.51e-01	0.297000	0.829000
GO:0030900 forebrain development	6	2.10e-01	0.296000	0.787000
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening	6	2.10e-01	0.296000	0.787000
GO:0030308 negative regulation of cell growth	14	5.63e-02	-0.296000	0.675000
GO:0048027 mRNA 5’-UTR binding	9	1.25e-01	-0.296000	0.767000
GO:0036064 ciliary basal body	10	1.07e-01	0.295000	0.767000
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis	5	2.53e-01	-0.295000	0.829000
GO:0001954 positive regulation of cell-matrix adhesion	7	1.77e-01	0.295000	0.767000
GO:0051059 NF-kappaB binding	8	1.49e-01	0.295000	0.767000
GO:0005078 MAP-kinase scaffold activity	5	2.54e-01	0.295000	0.829000
GO:0042177 negative regulation of protein catabolic process	7	1.78e-01	0.295000	0.767000
GO:0050765 negative regulation of phagocytosis	7	1.79e-01	-0.294000	0.767000
GO:0030863 cortical cytoskeleton	10	1.08e-01	0.294000	0.767000
GO:0046966 nuclear thyroid hormone receptor binding	11	9.45e-02	0.292000	0.767000
GO:0061470 T follicular helper cell differentiation	5	2.60e-01	0.292000	0.829000
GO:0018105 peptidyl-serine phosphorylation	31	5.35e-03	0.291000	0.411000
GO:0030705 cytoskeleton-dependent intracellular transport	6	2.19e-01	-0.291000	0.804000
GO:0042056 chemoattractant activity	7	1.85e-01	-0.290000	0.767000
GO:0016442 RISC complex	6	2.19e-01	-0.290000	0.804000
GO:0060348 bone development	8	1.57e-01	0.290000	0.767000
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors	9	1.34e-01	-0.289000	0.767000
GO:0042613 MHC class II protein complex	10	1.14e-01	-0.289000	0.767000
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle	7	1.88e-01	-0.288000	0.767000
GO:0043434 response to peptide hormone	7	1.88e-01	-0.288000	0.767000
GO:0030501 positive regulation of bone mineralization	6	2.24e-01	0.287000	0.813000
GO:0006310 DNA recombination	5	2.68e-01	-0.286000	0.829000
GO:0015631 tubulin binding	7	1.92e-01	-0.285000	0.771000
GO:0016239 positive regulation of macroautophagy	5	2.71e-01	0.285000	0.829000
GO:0051592 response to calcium ion	11	1.04e-01	0.284000	0.767000
GO:0009615 response to virus	27	1.13e-02	-0.284000	0.491000
GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain	6	2.32e-01	-0.282000	0.826000
GO:0070418 DNA-dependent protein kinase complex	5	2.76e-01	0.282000	0.829000
GO:0036289 peptidyl-serine autophosphorylation	5	2.78e-01	0.281000	0.829000
GO:0045672 positive regulation of osteoclast differentiation	5	2.78e-01	0.281000	0.829000
GO:0035456 response to interferon-beta	5	2.78e-01	-0.281000	0.829000
GO:0005125 cytokine activity	9	1.47e-01	-0.280000	0.767000
GO:0101005 deubiquitinase activity	5	2.79e-01	0.280000	0.829000
GO:0032211 negative regulation of telomere maintenance via telomerase	5	2.80e-01	-0.280000	0.829000
GO:0031012 extracellular matrix	8	1.72e-01	-0.279000	0.767000
GO:0035578 azurophil granule lumen	25	1.63e-02	-0.279000	0.554000
GO:0043484 regulation of RNA splicing	20	3.16e-02	-0.279000	0.594000
GO:0035739 CD4-positive, alpha-beta T cell proliferation	5	2.81e-01	0.279000	0.829000
GO:0048167 regulation of synaptic plasticity	9	1.49e-01	-0.279000	0.767000
GO:0001938 positive regulation of endothelial cell proliferation	7	2.03e-01	0.279000	0.781000
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	5	2.83e-01	-0.278000	0.829000
GO:0015459 potassium channel regulator activity	5	2.83e-01	-0.277000	0.829000
GO:0002523 leukocyte migration involved in inflammatory response	5	2.85e-01	-0.277000	0.829000
GO:0032931 histone H3K56 acetyltransferase activity	8	1.76e-01	0.277000	0.767000
GO:0043992 histone H3K9 acetyltransferase activity	8	1.76e-01	0.277000	0.767000
GO:0043993 histone H3K18 acetyltransferase activity	8	1.76e-01	0.277000	0.767000
GO:0043994 histone H3K23 acetyltransferase activity	8	1.76e-01	0.277000	0.767000
GO:0043999 histone H2AK5 acetyltransferase activity	8	1.76e-01	0.277000	0.767000
GO:0044012 histone H2AK9 acetyltransferase activity	8	1.76e-01	0.277000	0.767000
GO:0044014 histone H2BK5 acetyltransferase activity	8	1.76e-01	0.277000	0.767000
GO:0044015 histone H2BK12 acetyltransferase activity	8	1.76e-01	0.277000	0.767000
GO:0044016 histone H3K4 acetyltransferase activity	8	1.76e-01	0.277000	0.767000
GO:0044017 histone H3K27 acetyltransferase activity	8	1.76e-01	0.277000	0.767000
GO:0044018 histone H3K36 acetyltransferase activity	8	1.76e-01	0.277000	0.767000
GO:0046972 histone H4K16 acetyltransferase activity	8	1.76e-01	0.277000	0.767000
GO:0140908 histone H3K122 acetyltransferase activity	8	1.76e-01	0.277000	0.767000
GO:0061631 ubiquitin conjugating enzyme activity	13	8.59e-02	-0.276000	0.767000
GO:0005776 autophagosome	17	5.01e-02	-0.276000	0.667000
GO:0001968 fibronectin binding	5	2.87e-01	0.276000	0.829000
GO:0071456 cellular response to hypoxia	18	4.43e-02	0.275000	0.650000
GO:0005697 telomerase holoenzyme complex	5	2.89e-01	0.274000	0.831000
GO:0051591 response to cAMP	7	2.10e-01	-0.274000	0.787000
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide	18	4.51e-02	-0.274000	0.655000
GO:0009653 anatomical structure morphogenesis	6	2.46e-01	0.274000	0.829000
GO:0004672 protein kinase activity	43	2.11e-03	0.274000	0.294000
GO:0019894 kinesin binding	6	2.48e-01	0.273000	0.829000
GO:0005246 calcium channel regulator activity	8	1.82e-01	-0.273000	0.767000
GO:0016235 aggresome	8	1.83e-01	-0.273000	0.767000
GO:0005764 lysosome	56	4.98e-04	-0.272000	0.121000
GO:0045071 negative regulation of viral genome replication	10	1.38e-01	-0.272000	0.767000
GO:0035976 transcription factor AP-1 complex	5	2.94e-01	0.271000	0.835000
GO:0008361 regulation of cell size	8	1.85e-01	0.271000	0.767000
GO:0038061 non-canonical NF-kappaB signal transduction	6	2.51e-01	-0.271000	0.829000
GO:0034450 ubiquitin-ubiquitin ligase activity	7	2.16e-01	-0.271000	0.802000
GO:0048146 positive regulation of fibroblast proliferation	8	1.86e-01	-0.271000	0.767000
GO:0005876 spindle microtubule	7	2.17e-01	0.270000	0.802000
GO:0007267 cell-cell signaling	16	6.30e-02	-0.270000	0.706000
GO:0036126 sperm flagellum	6	2.54e-01	-0.269000	0.829000
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle	8	1.90e-01	-0.268000	0.767000
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway	5	3.00e-01	-0.268000	0.840000
GO:0071474 cellular hyperosmotic response	5	3.01e-01	0.267000	0.841000
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding	6	2.60e-01	-0.266000	0.829000
GO:0009636 response to toxic substance	15	7.63e-02	-0.265000	0.743000
GO:0004402 histone acetyltransferase activity	8	1.95e-01	0.265000	0.771000
GO:0045786 negative regulation of cell cycle	5	3.05e-01	-0.265000	0.841000
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	7	2.26e-01	-0.265000	0.818000
GO:0050678 regulation of epithelial cell proliferation	5	3.07e-01	0.264000	0.841000
GO:0044305 calyx of Held	6	2.64e-01	0.264000	0.829000
GO:0005902 microvillus	11	1.32e-01	0.263000	0.767000
GO:0030374 nuclear receptor coactivator activity	15	7.94e-02	0.263000	0.743000
GO:0000786 nucleosome	7	2.30e-01	0.263000	0.826000
GO:0031527 filopodium membrane	5	3.10e-01	0.262000	0.843000
GO:0097718 disordered domain specific binding	10	1.53e-01	0.262000	0.767000
GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process	7	2.33e-01	-0.261000	0.826000
GO:0030336 negative regulation of cell migration	21	3.94e-02	0.261000	0.639000
GO:0070972 protein localization to endoplasmic reticulum	5	3.14e-01	-0.261000	0.845000
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway	10	1.56e-01	0.260000	0.767000
GO:0008009 chemokine activity	8	2.05e-01	-0.259000	0.784000
GO:0001975 response to amphetamine	6	2.73e-01	-0.259000	0.829000
GO:0048488 synaptic vesicle endocytosis	10	1.59e-01	0.258000	0.767000
GO:0006611 protein export from nucleus	7	2.38e-01	-0.258000	0.829000
GO:0090303 positive regulation of wound healing	6	2.75e-01	0.258000	0.829000
GO:0008584 male gonad development	7	2.38e-01	0.258000	0.829000
GO:0006469 negative regulation of protein kinase activity	9	1.81e-01	0.258000	0.767000
GO:0001673 male germ cell nucleus	5	3.19e-01	-0.258000	0.851000
GO:0032688 negative regulation of interferon-beta production	5	3.21e-01	-0.257000	0.851000
GO:0071560 cellular response to transforming growth factor beta stimulus	13	1.12e-01	0.256000	0.767000
GO:0006874 intracellular calcium ion homeostasis	11	1.43e-01	-0.256000	0.767000
GO:0030904 retromer complex	7	2.43e-01	-0.256000	0.829000
GO:0043020 NADPH oxidase complex	6	2.82e-01	-0.254000	0.829000
GO:0001530 lipopolysaccharide binding	9	1.88e-01	-0.254000	0.767000
GO:0060544 regulation of necroptotic process	6	2.84e-01	0.253000	0.829000
GO:0042327 positive regulation of phosphorylation	5	3.28e-01	-0.253000	0.854000
GO:0019887 protein kinase regulator activity	5	3.29e-01	0.253000	0.854000
GO:0005684 U2-type spliceosomal complex	6	2.87e-01	-0.252000	0.829000
GO:1903241 U2-type prespliceosome assembly	6	2.87e-01	-0.252000	0.829000
GO:0098761 cellular response to interleukin-7	5	3.31e-01	0.252000	0.855000
GO:0071044 histone mRNA catabolic process	6	2.87e-01	-0.251000	0.829000
GO:0050778 positive regulation of immune response	10	1.72e-01	-0.250000	0.767000
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway	5	3.34e-01	-0.250000	0.855000
GO:0030890 positive regulation of B cell proliferation	10	1.74e-01	-0.249000	0.767000
GO:1990518 single-stranded 3’-5’ DNA helicase activity	7	2.55e-01	-0.249000	0.829000
GO:2000773 negative regulation of cellular senescence	6	2.92e-01	-0.249000	0.831000
GO:0044183 protein folding chaperone	9	1.97e-01	-0.249000	0.776000
GO:0016197 endosomal transport	10	1.76e-01	-0.248000	0.767000
GO:0032868 response to insulin	9	2.00e-01	0.247000	0.777000
GO:0016925 protein sumoylation	9	2.02e-01	-0.246000	0.780000
GO:0140566 histone reader activity	6	2.98e-01	-0.246000	0.837000
GO:0060391 positive regulation of SMAD protein signal transduction	5	3.42e-01	0.246000	0.856000
GO:0001771 immunological synapse formation	5	3.42e-01	0.246000	0.856000
GO:0005875 microtubule associated complex	5	3.43e-01	0.245000	0.856000
GO:0045730 respiratory burst	9	2.05e-01	-0.245000	0.783000
GO:0003779 actin binding	55	1.99e-03	0.244000	0.294000
GO:0000423 mitophagy	11	1.63e-01	-0.244000	0.767000
GO:0007035 vacuolar acidification	10	1.83e-01	-0.244000	0.767000
GO:0006909 phagocytosis	16	9.26e-02	0.244000	0.767000
GO:0034975 protein folding in endoplasmic reticulum	7	2.65e-01	-0.244000	0.829000
GO:0035278 miRNA-mediated gene silencing by inhibition of translation	5	3.47e-01	0.243000	0.860000
GO:0006612 protein targeting to membrane	7	2.66e-01	-0.243000	0.829000
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway	13	1.30e-01	0.243000	0.767000
GO:2000767 positive regulation of cytoplasmic translation	9	2.09e-01	0.243000	0.787000
GO:0043296 apical junction complex	5	3.48e-01	0.243000	0.862000
GO:0003713 transcription coactivator activity	56	1.97e-03	0.242000	0.294000
GO:0050848 regulation of calcium-mediated signaling	5	3.49e-01	0.242000	0.863000
GO:0005689 U12-type spliceosomal complex	7	2.69e-01	-0.242000	0.829000
GO:0060218 hematopoietic stem cell differentiation	5	3.51e-01	0.241000	0.863000
GO:0032922 circadian regulation of gene expression	17	8.64e-02	0.241000	0.767000
GO:0045070 positive regulation of viral genome replication	8	2.39e-01	0.241000	0.829000
GO:0033290 eukaryotic 48S preinitiation complex	10	1.88e-01	0.241000	0.767000
GO:0043235 receptor complex	13	1.35e-01	0.241000	0.767000
GO:0060041 retina development in camera-type eye	10	1.89e-01	-0.240000	0.767000
GO:0048015 phosphatidylinositol-mediated signaling	7	2.73e-01	-0.240000	0.829000
GO:0042974 nuclear retinoic acid receptor binding	5	3.54e-01	-0.240000	0.863000
GO:0000407 phagophore assembly site	7	2.75e-01	-0.239000	0.829000
GO:0035335 peptidyl-tyrosine dephosphorylation	5	3.56e-01	-0.239000	0.863000
GO:0050699 WW domain binding	5	3.56e-01	-0.239000	0.863000
GO:0007595 lactation	6	3.13e-01	0.238000	0.844000
GO:0005882 intermediate filament	7	2.76e-01	-0.238000	0.829000
GO:2000406 positive regulation of T cell migration	9	2.17e-01	0.238000	0.802000
GO:0043030 regulation of macrophage activation	5	3.59e-01	-0.237000	0.866000
GO:1904724 tertiary granule lumen	15	1.13e-01	-0.237000	0.767000
GO:0045785 positive regulation of cell adhesion	8	2.47e-01	0.237000	0.829000
GO:0005771 multivesicular body	7	2.79e-01	-0.237000	0.829000
GO:0000792 heterochromatin	6	3.20e-01	-0.235000	0.851000
GO:0030141 secretory granule	9	2.24e-01	-0.235000	0.813000
GO:0032956 regulation of actin cytoskeleton organization	21	6.39e-02	0.235000	0.706000
GO:0043021 ribonucleoprotein complex binding	9	2.25e-01	0.234000	0.815000
GO:0007405 neuroblast proliferation	6	3.22e-01	0.234000	0.853000
GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	7	2.85e-01	0.234000	0.829000
GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	7	2.85e-01	0.234000	0.829000
GO:0007498 mesoderm development	6	3.24e-01	-0.233000	0.854000
GO:0006337 nucleosome disassembly	5	3.68e-01	0.233000	0.871000
GO:0007166 cell surface receptor signaling pathway	33	2.29e-02	0.231000	0.594000
GO:0071007 U2-type catalytic step 2 spliceosome	5	3.73e-01	-0.230000	0.880000
GO:0031492 nucleosomal DNA binding	10	2.09e-01	0.230000	0.787000
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	5	3.74e-01	0.230000	0.880000
GO:0032930 positive regulation of superoxide anion generation	10	2.09e-01	0.230000	0.787000
GO:0004129 cytochrome-c oxidase activity	10	2.10e-01	-0.230000	0.787000
GO:0055085 transmembrane transport	6	3.31e-01	-0.229000	0.855000
GO:0005795 Golgi stack	5	3.75e-01	-0.229000	0.881000
GO:0140693 molecular condensate scaffold activity	14	1.39e-01	-0.229000	0.767000
GO:0070979 protein K11-linked ubiquitination	12	1.71e-01	-0.229000	0.767000
GO:0005522 profilin binding	6	3.36e-01	0.227000	0.855000
GO:0005721 pericentric heterochromatin	6	3.36e-01	-0.227000	0.855000
GO:0004697 diacylglycerol-dependent serine/threonine kinase activity	5	3.80e-01	0.227000	0.881000
GO:0016592 mediator complex	6	3.38e-01	0.226000	0.856000
GO:0060440 trachea formation	5	3.82e-01	0.226000	0.881000
GO:0031904 endosome lumen	5	3.83e-01	-0.226000	0.881000
GO:0051603 proteolysis involved in protein catabolic process	13	1.60e-01	-0.226000	0.767000
GO:0001678 intracellular glucose homeostasis	5	3.84e-01	0.225000	0.882000
GO:0031640 killing of cells of another organism	17	1.10e-01	-0.225000	0.767000
GO:0016922 nuclear receptor binding	17	1.11e-01	0.224000	0.767000
GO:0046965 nuclear retinoid X receptor binding	6	3.43e-01	0.224000	0.856000
GO:0071735 IgG immunoglobulin complex	5	3.87e-01	0.224000	0.883000
GO:0090160 Golgi to lysosome transport	5	3.87e-01	0.224000	0.883000
GO:0048545 response to steroid hormone	5	3.88e-01	0.223000	0.883000
GO:0005694 chromosome	26	5.03e-02	0.223000	0.667000
GO:0002503 peptide antigen assembly with MHC class II protein complex	9	2.48e-01	-0.223000	0.829000
GO:0030168 platelet activation	13	1.65e-01	0.223000	0.767000
GO:0008277 regulation of G protein-coupled receptor signaling pathway	7	3.09e-01	-0.223000	0.841000
GO:0032480 negative regulation of type I interferon production	8	2.78e-01	0.222000	0.829000
GO:0000242 pericentriolar material	5	3.91e-01	-0.222000	0.883000
GO:0030593 neutrophil chemotaxis	23	6.71e-02	-0.222000	0.711000
GO:0007095 mitotic G2 DNA damage checkpoint signaling	9	2.51e-01	-0.222000	0.829000
GO:0031093 platelet alpha granule lumen	14	1.53e-01	0.221000	0.767000
GO:0007179 transforming growth factor beta receptor signaling pathway	17	1.17e-01	0.221000	0.767000
GO:1902895 positive regulation of miRNA transcription	13	1.70e-01	0.221000	0.767000
GO:0048255 mRNA stabilization	9	2.53e-01	0.221000	0.829000
GO:0032438 melanosome organization	5	3.94e-01	0.221000	0.883000
GO:0032722 positive regulation of chemokine production	6	3.51e-01	-0.220000	0.863000
GO:0070971 endoplasmic reticulum exit site	5	3.95e-01	0.220000	0.883000
GO:0002862 negative regulation of inflammatory response to antigenic stimulus	10	2.30e-01	0.220000	0.826000
GO:0022904 respiratory electron transport chain	7	3.16e-01	-0.219000	0.849000
GO:0007030 Golgi organization	20	9.17e-02	0.219000	0.767000
GO:0032757 positive regulation of interleukin-8 production	13	1.74e-01	-0.219000	0.767000
GO:0031092 platelet alpha granule membrane	8	2.86e-01	0.218000	0.829000
GO:0000400 four-way junction DNA binding	5	3.99e-01	-0.218000	0.886000
GO:0016301 kinase activity	10	2.34e-01	0.218000	0.827000
GO:0019900 kinase binding	23	7.22e-02	-0.218000	0.742000
GO:0022627 cytosolic small ribosomal subunit	36	2.50e-02	-0.218000	0.594000
GO:0045040 protein insertion into mitochondrial outer membrane	5	4.00e-01	0.218000	0.886000
GO:0006487 protein N-linked glycosylation	8	2.88e-01	-0.217000	0.830000
GO:0030665 clathrin-coated vesicle membrane	9	2.60e-01	-0.217000	0.829000
GO:0035331 negative regulation of hippo signaling	5	4.02e-01	0.217000	0.886000
GO:0051247 positive regulation of protein metabolic process	5	4.02e-01	-0.217000	0.886000
GO:0016282 eukaryotic 43S preinitiation complex	11	2.14e-01	0.217000	0.800000
GO:0007213 G protein-coupled acetylcholine receptor signaling pathway	6	3.59e-01	0.217000	0.866000
GO:0045454 cell redox homeostasis	6	3.62e-01	-0.215000	0.866000
GO:0072686 mitotic spindle	23	7.58e-02	0.215000	0.743000
GO:0060325 face morphogenesis	5	4.06e-01	0.215000	0.886000
GO:0072673 lamellipodium morphogenesis	5	4.06e-01	-0.215000	0.886000
GO:0048487 beta-tubulin binding	12	2.00e-01	-0.215000	0.777000
GO:0009267 cellular response to starvation	15	1.52e-01	0.214000	0.767000
GO:0031295 T cell costimulation	10	2.43e-01	0.214000	0.829000
GO:0019955 cytokine binding	9	2.68e-01	0.214000	0.829000
GO:0050750 low-density lipoprotein particle receptor binding	5	4.10e-01	0.213000	0.886000
GO:0050918 positive chemotaxis	9	2.70e-01	-0.213000	0.829000
GO:0032040 small-subunit processome	23	7.93e-02	-0.213000	0.743000
GO:0070527 platelet aggregation	18	1.20e-01	0.213000	0.767000
GO:0001501 skeletal system development	9	2.72e-01	-0.212000	0.829000
GO:0004712 protein serine/threonine/tyrosine kinase activity	6	3.72e-01	0.211000	0.878000
GO:0015935 small ribosomal subunit	13	1.90e-01	-0.211000	0.767000
GO:0001618 virus receptor activity	13	1.90e-01	0.211000	0.767000
GO:0038095 Fc-epsilon receptor signaling pathway	7	3.36e-01	0.210000	0.855000
GO:0002218 activation of innate immune response	13	1.92e-01	0.210000	0.771000
GO:0035577 azurophil granule membrane	23	8.41e-02	-0.209000	0.767000
GO:0000987 cis-regulatory region sequence-specific DNA binding	9	2.79e-01	0.209000	0.829000
GO:0042405 nuclear inclusion body	5	4.20e-01	0.209000	0.891000
GO:0005543 phospholipid binding	18	1.28e-01	0.208000	0.767000
GO:0033574 response to testosterone	6	3.79e-01	-0.208000	0.881000
GO:0051146 striated muscle cell differentiation	5	4.23e-01	-0.207000	0.891000
GO:0030177 positive regulation of Wnt signaling pathway	8	3.12e-01	-0.207000	0.844000
GO:0019827 stem cell population maintenance	5	4.24e-01	-0.207000	0.891000
GO:0001889 liver development	13	1.99e-01	0.207000	0.777000
GO:0007080 mitotic metaphase chromosome alignment	5	4.25e-01	0.206000	0.891000
GO:0007029 endoplasmic reticulum organization	6	3.83e-01	0.206000	0.881000
GO:0035198 miRNA binding	11	2.40e-01	0.205000	0.829000
GO:0043202 lysosomal lumen	14	1.86e-01	-0.205000	0.767000
GO:0034452 dynactin binding	5	4.29e-01	0.205000	0.891000
GO:1990756 ubiquitin-like ligase-substrate adaptor activity	11	2.41e-01	0.205000	0.829000
GO:0048009 insulin-like growth factor receptor signaling pathway	9	2.90e-01	0.204000	0.831000
GO:0036016 cellular response to interleukin-3	5	4.30e-01	0.204000	0.891000
GO:0043542 endothelial cell migration	9	2.91e-01	-0.204000	0.831000
GO:0000307 cyclin-dependent protein kinase holoenzyme complex	6	3.90e-01	-0.203000	0.883000
GO:0061157 mRNA destabilization	5	4.35e-01	0.202000	0.893000
GO:0046854 phosphatidylinositol phosphate biosynthetic process	5	4.36e-01	-0.201000	0.893000
GO:0001965 G-protein alpha-subunit binding	5	4.37e-01	-0.201000	0.893000
GO:0035613 RNA stem-loop binding	5	4.38e-01	-0.201000	0.893000
GO:0006325 chromatin organization	27	7.36e-02	0.200000	0.743000
GO:0006282 regulation of DNA repair	8	3.28e-01	-0.200000	0.854000
GO:0030175 filopodium	15	1.82e-01	0.200000	0.767000
GO:0010468 regulation of gene expression	31	5.61e-02	0.200000	0.675000
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane	15	1.83e-01	-0.199000	0.767000
GO:0051279 regulation of release of sequestered calcium ion into cytosol	7	3.64e-01	0.199000	0.866000
GO:0006465 signal peptide processing	5	4.43e-01	-0.199000	0.894000
GO:0007224 smoothened signaling pathway	7	3.64e-01	-0.198000	0.866000
GO:0140694 membraneless organelle assembly	5	4.43e-01	-0.198000	0.894000
GO:0000380 alternative mRNA splicing, via spliceosome	9	3.05e-01	0.198000	0.841000
GO:0051219 phosphoprotein binding	10	2.81e-01	0.198000	0.829000
GO:0051493 regulation of cytoskeleton organization	8	3.34e-01	0.198000	0.855000
GO:0000146 microfilament motor activity	6	4.03e-01	0.198000	0.886000
GO:0046329 negative regulation of JNK cascade	6	4.05e-01	0.197000	0.886000
GO:0036408 histone H3K14 acetyltransferase activity	9	3.08e-01	0.197000	0.841000
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis	9	3.08e-01	0.197000	0.841000
GO:0043995 histone H4K5 acetyltransferase activity	9	3.08e-01	0.197000	0.841000
GO:0043996 histone H4K8 acetyltransferase activity	9	3.08e-01	0.197000	0.841000
GO:0043997 histone H4K12 acetyltransferase activity	9	3.08e-01	0.197000	0.841000
GO:0030838 positive regulation of actin filament polymerization	14	2.05e-01	0.197000	0.783000
GO:1903140 regulation of establishment of endothelial barrier	5	4.48e-01	0.196000	0.894000
GO:0046488 phosphatidylinositol metabolic process	7	3.70e-01	-0.196000	0.874000
GO:1904262 negative regulation of TORC1 signaling	6	4.07e-01	0.196000	0.886000
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding	9	3.13e-01	0.195000	0.844000
GO:0009378 four-way junction helicase activity	6	4.10e-01	-0.195000	0.886000
GO:0036121 double-stranded DNA helicase activity	6	4.10e-01	-0.195000	0.886000
GO:0061749 forked DNA-dependent helicase activity	6	4.10e-01	-0.195000	0.886000
GO:0010634 positive regulation of epithelial cell migration	11	2.66e-01	0.194000	0.829000
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage	11	2.66e-01	-0.194000	0.829000
GO:0001932 regulation of protein phosphorylation	6	4.11e-01	-0.194000	0.886000
GO:0008134 transcription factor binding	6	4.12e-01	-0.194000	0.886000
GO:0048821 erythrocyte development	6	4.12e-01	0.194000	0.886000
GO:0050728 negative regulation of inflammatory response	23	1.10e-01	-0.194000	0.767000
GO:0001669 acrosomal vesicle	8	3.49e-01	-0.192000	0.862000
GO:0045332 phospholipid translocation	5	4.59e-01	-0.192000	0.894000
GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction	15	2.02e-01	-0.191000	0.780000
GO:0034113 heterotypic cell-cell adhesion	10	2.98e-01	-0.191000	0.837000
GO:0010811 positive regulation of cell-substrate adhesion	5	4.62e-01	0.190000	0.894000
GO:0007411 axon guidance	11	2.77e-01	0.190000	0.829000
GO:0043531 ADP binding	8	3.53e-01	-0.190000	0.863000
GO:0032703 negative regulation of interleukin-2 production	5	4.63e-01	0.190000	0.894000
GO:0000278 mitotic cell cycle	12	2.57e-01	-0.189000	0.829000
GO:0001772 immunological synapse	21	1.35e-01	0.189000	0.767000
GO:0051963 regulation of synapse assembly	5	4.64e-01	-0.189000	0.894000
GO:0005884 actin filament	26	9.80e-02	0.189000	0.767000
GO:0097386 glial cell projection	6	4.25e-01	0.189000	0.891000
GO:0006508 proteolysis	46	2.92e-02	-0.188000	0.594000
GO:0070373 negative regulation of ERK1 and ERK2 cascade	8	3.58e-01	0.188000	0.866000
GO:0048870 cell motility	12	2.63e-01	0.187000	0.829000
GO:0043679 axon terminus	5	4.69e-01	0.187000	0.894000
GO:0005637 nuclear inner membrane	7	3.92e-01	-0.187000	0.883000
GO:0042832 defense response to protozoan	7	3.92e-01	0.187000	0.883000
GO:0031594 neuromuscular junction	8	3.63e-01	0.186000	0.866000
GO:0048268 clathrin coat assembly	8	3.63e-01	0.186000	0.866000
GO:0009952 anterior/posterior pattern specification	6	4.33e-01	0.185000	0.893000
GO:0051087 protein-folding chaperone binding	19	1.64e-01	0.185000	0.767000
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II	15	2.16e-01	-0.185000	0.802000
GO:0045732 positive regulation of protein catabolic process	22	1.35e-01	0.185000	0.767000
GO:0030030 cell projection organization	5	4.76e-01	0.184000	0.894000
GO:0032968 positive regulation of transcription elongation by RNA polymerase II	5	4.77e-01	0.184000	0.894000
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism	13	2.53e-01	-0.184000	0.829000
GO:0045595 regulation of cell differentiation	9	3.41e-01	-0.184000	0.856000
GO:0030334 regulation of cell migration	15	2.21e-01	0.183000	0.808000
GO:0045597 positive regulation of cell differentiation	13	2.54e-01	0.183000	0.829000
GO:0006952 defense response	13	2.56e-01	-0.182000	0.829000
GO:0048678 response to axon injury	7	4.05e-01	0.182000	0.886000
GO:0016363 nuclear matrix	29	9.18e-02	0.182000	0.767000
GO:0031730 CCR5 chemokine receptor binding	5	4.82e-01	-0.182000	0.894000
GO:0051209 release of sequestered calcium ion into cytosol	10	3.21e-01	0.182000	0.852000
GO:0051402 neuron apoptotic process	17	1.97e-01	0.181000	0.776000
GO:0140105 interleukin-10-mediated signaling pathway	5	4.83e-01	-0.181000	0.894000
GO:0007186 G protein-coupled receptor signaling pathway	36	6.23e-02	0.181000	0.706000
GO:0050684 regulation of mRNA processing	5	4.84e-01	-0.181000	0.894000
GO:0000281 mitotic cytokinesis	8	3.76e-01	0.181000	0.881000
GO:0033627 cell adhesion mediated by integrin	10	3.25e-01	0.180000	0.854000
GO:0046330 positive regulation of JNK cascade	19	1.79e-01	-0.179000	0.767000
GO:0015030 Cajal body	8	3.82e-01	-0.179000	0.881000
GO:0001732 formation of cytoplasmic translation initiation complex	10	3.29e-01	0.179000	0.854000
GO:0045591 positive regulation of regulatory T cell differentiation	7	4.14e-01	-0.179000	0.886000
GO:0030216 keratinocyte differentiation	11	3.07e-01	-0.179000	0.841000
GO:0045579 positive regulation of B cell differentiation	5	4.90e-01	0.178000	0.894000
GO:0019882 antigen processing and presentation	9	3.56e-01	-0.178000	0.863000
GO:0043022 ribosome binding	13	2.68e-01	0.178000	0.829000
GO:0004930 G protein-coupled receptor activity	5	4.92e-01	0.178000	0.894000
GO:0030014 CCR4-NOT complex	5	4.92e-01	0.178000	0.894000
GO:0019774 proteasome core complex, beta-subunit complex	5	4.93e-01	-0.177000	0.894000
GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	5	4.94e-01	0.177000	0.894000
GO:0048873 homeostasis of number of cells within a tissue	8	3.88e-01	-0.177000	0.883000
GO:0003684 damaged DNA binding	7	4.19e-01	0.177000	0.891000
GO:0048812 neuron projection morphogenesis	13	2.72e-01	-0.177000	0.829000
GO:0016241 regulation of macroautophagy	11	3.12e-01	-0.177000	0.844000
GO:0006954 inflammatory response	70	1.22e-02	-0.176000	0.518000
GO:0002230 positive regulation of defense response to virus by host	6	4.55e-01	0.176000	0.894000
GO:0005975 carbohydrate metabolic process	6	4.55e-01	-0.176000	0.894000
GO:0043433 negative regulation of DNA-binding transcription factor activity	6	4.55e-01	-0.176000	0.894000
GO:0071223 cellular response to lipoteichoic acid	5	4.96e-01	0.176000	0.894000
GO:0051492 regulation of stress fiber assembly	5	4.97e-01	0.176000	0.894000
GO:0042220 response to cocaine	6	4.58e-01	-0.175000	0.894000
GO:0046627 negative regulation of insulin receptor signaling pathway	9	3.64e-01	-0.175000	0.866000
GO:0009887 animal organ morphogenesis	7	4.24e-01	-0.175000	0.891000
GO:0008543 fibroblast growth factor receptor signaling pathway	7	4.24e-01	0.175000	0.891000
GO:0050772 positive regulation of axonogenesis	5	5.00e-01	-0.175000	0.894000
GO:0016787 hydrolase activity	10	3.41e-01	0.174000	0.856000
GO:0005912 adherens junction	26	1.26e-01	0.174000	0.767000
GO:0007346 regulation of mitotic cell cycle	12	2.98e-01	-0.174000	0.838000
GO:0035458 cellular response to interferon-beta	10	3.43e-01	-0.174000	0.856000
GO:0045259 proton-transporting ATP synthase complex	12	2.99e-01	-0.174000	0.838000
GO:0045995 regulation of embryonic development	6	4.62e-01	0.174000	0.894000
GO:0016328 lateral plasma membrane	7	4.28e-01	-0.173000	0.891000
GO:0034504 protein localization to nucleus	8	3.98e-01	-0.173000	0.886000
GO:0030332 cyclin binding	7	4.29e-01	0.173000	0.891000
GO:0035035 histone acetyltransferase binding	7	4.29e-01	0.173000	0.891000
GO:0019843 rRNA binding	12	3.02e-01	-0.173000	0.841000
GO:0032570 response to progesterone	11	3.23e-01	-0.173000	0.854000
GO:0006606 protein import into nucleus	20	1.84e-01	-0.173000	0.767000
GO:0038023 signaling receptor activity	24	1.46e-01	-0.173000	0.767000
GO:0032755 positive regulation of interleukin-6 production	24	1.46e-01	-0.172000	0.767000
GO:0061640 cytoskeleton-dependent cytokinesis	5	5.07e-01	-0.172000	0.894000
GO:0000976 transcription cis-regulatory region binding	43	5.40e-02	0.172000	0.667000
GO:0030521 androgen receptor signaling pathway	8	4.04e-01	0.171000	0.886000
GO:0005681 spliceosomal complex	29	1.14e-01	-0.171000	0.767000
GO:0008201 heparin binding	11	3.29e-01	-0.170000	0.855000
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	9	3.78e-01	-0.170000	0.881000
GO:0045824 negative regulation of innate immune response	5	5.10e-01	-0.170000	0.894000
GO:0062023 collagen-containing extracellular matrix	40	6.52e-02	-0.170000	0.708000
GO:0006302 double-strand break repair	7	4.37e-01	0.170000	0.893000
GO:0071004 U2-type prespliceosome	8	4.07e-01	-0.170000	0.886000
GO:0071682 endocytic vesicle lumen	6	4.73e-01	0.170000	0.894000
GO:0001540 amyloid-beta binding	14	2.74e-01	-0.169000	0.829000
GO:0070371 ERK1 and ERK2 cascade	9	3.80e-01	0.169000	0.881000
GO:0071404 cellular response to low-density lipoprotein particle stimulus	7	4.40e-01	0.169000	0.894000
GO:0000398 mRNA splicing, via spliceosome	43	5.86e-02	-0.168000	0.688000
GO:0019903 protein phosphatase binding	27	1.33e-01	0.168000	0.767000
GO:0005769 early endosome	49	4.40e-02	0.168000	0.650000
GO:0070886 positive regulation of calcineurin-NFAT signaling cascade	6	4.76e-01	-0.168000	0.894000
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway	14	2.79e-01	0.168000	0.829000
GO:0008154 actin polymerization or depolymerization	7	4.43e-01	0.168000	0.894000
GO:0016324 apical plasma membrane	29	1.21e-01	-0.168000	0.767000
GO:1900227 positive regulation of NLRP3 inflammasome complex assembly	6	4.78e-01	0.168000	0.894000
GO:0042789 mRNA transcription by RNA polymerase II	14	2.79e-01	0.168000	0.829000
GO:0006887 exocytosis	16	2.48e-01	-0.167000	0.829000
GO:0042274 ribosomal small subunit biogenesis	24	1.59e-01	-0.167000	0.767000
GO:0051020 GTPase binding	12	3.18e-01	0.167000	0.851000
GO:0071466 cellular response to xenobiotic stimulus	9	3.87e-01	-0.167000	0.883000
GO:0035902 response to immobilization stress	5	5.19e-01	-0.167000	0.894000
GO:0046983 protein dimerization activity	16	2.51e-01	0.167000	0.829000
GO:0045860 positive regulation of protein kinase activity	16	2.51e-01	-0.167000	0.829000
GO:0005938 cell cortex	47	5.11e-02	0.166000	0.667000
GO:0070372 regulation of ERK1 and ERK2 cascade	7	4.51e-01	0.165000	0.894000
GO:0001525 angiogenesis	35	9.40e-02	0.165000	0.767000
GO:0048489 synaptic vesicle transport	5	5.24e-01	-0.165000	0.894000
GO:0003785 actin monomer binding	7	4.53e-01	0.164000	0.894000
GO:0051865 protein autoubiquitination	15	2.73e-01	0.164000	0.829000
GO:0019003 GDP binding	13	3.08e-01	-0.164000	0.841000
GO:0007159 leukocyte cell-cell adhesion	13	3.09e-01	0.164000	0.841000
GO:0006367 transcription initiation at RNA polymerase II promoter	5	5.27e-01	-0.164000	0.894000
GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	5	5.27e-01	-0.164000	0.894000
GO:0031258 lamellipodium membrane	5	5.29e-01	0.163000	0.894000
GO:0031526 brush border membrane	5	5.30e-01	0.163000	0.894000
GO:0034332 adherens junction organization	5	5.30e-01	-0.163000	0.894000
GO:0042101 T cell receptor complex	5	5.30e-01	0.163000	0.894000
GO:0042632 cholesterol homeostasis	8	4.27e-01	0.163000	0.891000
GO:0000791 euchromatin	11	3.52e-01	0.162000	0.863000
GO:0006754 ATP biosynthetic process	6	4.93e-01	-0.162000	0.894000
GO:0045059 positive thymic T cell selection	5	5.31e-01	-0.162000	0.894000
GO:0007623 circadian rhythm	11	3.55e-01	0.162000	0.863000
GO:0005790 smooth endoplasmic reticulum	9	4.04e-01	-0.161000	0.886000
GO:0035861 site of double-strand break	17	2.54e-01	0.161000	0.829000
GO:0042826 histone deacetylase binding	23	1.86e-01	0.160000	0.767000
GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib	5	5.36e-01	0.160000	0.894000
GO:0002486 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	5	5.36e-01	0.160000	0.894000
GO:0072559 NLRP3 inflammasome complex	5	5.36e-01	-0.160000	0.894000
GO:0043931 ossification involved in bone maturation	5	5.38e-01	0.159000	0.894000
GO:0106310 protein serine kinase activity	70	2.36e-02	0.159000	0.594000
GO:0034220 monoatomic ion transmembrane transport	8	4.37e-01	0.159000	0.893000
GO:0097194 execution phase of apoptosis	7	4.67e-01	0.159000	0.894000
GO:0030742 GTP-dependent protein binding	5	5.40e-01	-0.159000	0.894000
GO:0042026 protein refolding	5	5.40e-01	0.158000	0.894000
GO:0042098 T cell proliferation	11	3.64e-01	0.158000	0.866000
GO:0032870 cellular response to hormone stimulus	5	5.41e-01	0.158000	0.894000
GO:0007286 spermatid development	10	3.88e-01	-0.158000	0.883000
GO:0019904 protein domain specific binding	51	5.42e-02	-0.158000	0.667000
GO:0051018 protein kinase A binding	5	5.42e-01	-0.158000	0.894000
GO:0030165 PDZ domain binding	10	3.90e-01	0.158000	0.883000
GO:0005643 nuclear pore	10	3.91e-01	-0.157000	0.883000
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c	7	4.74e-01	-0.156000	0.894000
GO:0045275 respiratory chain complex III	7	4.74e-01	-0.156000	0.894000
GO:0005852 eukaryotic translation initiation factor 3 complex	10	3.94e-01	0.156000	0.883000
GO:0051168 nuclear export	6	5.09e-01	-0.156000	0.894000
GO:0007584 response to nutrient	7	4.76e-01	-0.156000	0.894000
GO:0005885 Arp2/3 protein complex	7	4.78e-01	-0.155000	0.894000
GO:0005801 cis-Golgi network	6	5.13e-01	-0.155000	0.894000
GO:0035914 skeletal muscle cell differentiation	6	5.13e-01	-0.155000	0.894000
GO:0004713 protein tyrosine kinase activity	19	2.46e-01	0.155000	0.829000
GO:2000353 positive regulation of endothelial cell apoptotic process	7	4.81e-01	0.154000	0.894000
GO:0097110 scaffold protein binding	18	2.60e-01	0.154000	0.829000
GO:0034198 cellular response to amino acid starvation	6	5.16e-01	0.153000	0.894000
GO:0044325 transmembrane transporter binding	33	1.31e-01	0.153000	0.767000
GO:1903428 positive regulation of reactive oxygen species biosynthetic process	6	5.16e-01	-0.153000	0.894000
GO:0061024 membrane organization	7	4.84e-01	-0.153000	0.894000
GO:0003725 double-stranded RNA binding	22	2.16e-01	0.153000	0.802000
GO:0048705 skeletal system morphogenesis	5	5.54e-01	0.153000	0.900000
GO:0030032 lamellipodium assembly	8	4.56e-01	0.152000	0.894000
GO:0007219 Notch signaling pathway	11	3.84e-01	0.152000	0.882000
GO:0050768 negative regulation of neurogenesis	6	5.20e-01	-0.152000	0.894000
GO:0000776 kinetochore	26	1.84e-01	0.152000	0.767000
GO:0006891 intra-Golgi vesicle-mediated transport	7	4.93e-01	0.150000	0.894000
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity	6	5.27e-01	-0.149000	0.894000
GO:1990404 NAD+-protein ADP-ribosyltransferase activity	6	5.27e-01	-0.149000	0.894000
GO:0051019 mitogen-activated protein kinase binding	5	5.64e-01	0.149000	0.904000
GO:0035332 positive regulation of hippo signaling	5	5.64e-01	-0.149000	0.904000
GO:0043408 regulation of MAPK cascade	8	4.68e-01	-0.148000	0.894000
GO:0030225 macrophage differentiation	6	5.31e-01	0.148000	0.894000
GO:0032735 positive regulation of interleukin-12 production	11	3.99e-01	0.147000	0.886000
GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	6	5.34e-01	0.147000	0.894000
GO:0007098 centrosome cycle	8	4.73e-01	0.147000	0.894000
GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	29	1.75e-01	-0.147000	0.767000
GO:0000228 nuclear chromosome	8	4.74e-01	0.147000	0.894000
GO:0007173 epidermal growth factor receptor signaling pathway	7	5.03e-01	-0.146000	0.894000
GO:0007254 JNK cascade	12	3.82e-01	0.146000	0.881000
GO:0044319 wound healing, spreading of cells	5	5.72e-01	0.146000	0.909000
GO:0003676 nucleic acid binding	9	4.50e-01	0.146000	0.894000
GO:0032091 negative regulation of protein binding	9	4.50e-01	-0.146000	0.894000
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process	11	4.05e-01	0.146000	0.886000
GO:1903561 extracellular vesicle	12	3.85e-01	0.145000	0.883000
GO:0035145 exon-exon junction complex	7	5.07e-01	0.145000	0.894000
GO:0101003 ficolin-1-rich granule membrane	22	2.43e-01	-0.145000	0.829000
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT	6	5.41e-01	-0.144000	0.894000
GO:0034605 cellular response to heat	8	4.82e-01	-0.144000	0.894000
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding	6	5.42e-01	0.144000	0.894000
GO:0042612 MHC class I protein complex	6	5.44e-01	0.143000	0.894000
GO:2000045 regulation of G1/S transition of mitotic cell cycle	17	3.08e-01	0.143000	0.841000
GO:0090543 Flemming body	9	4.59e-01	0.143000	0.894000
GO:0030041 actin filament polymerization	11	4.13e-01	0.143000	0.886000
GO:0045055 regulated exocytosis	5	5.81e-01	-0.143000	0.913000
GO:0006470 protein dephosphorylation	18	2.97e-01	0.143000	0.837000
GO:0051028 mRNA transport	16	3.25e-01	-0.143000	0.854000
GO:0048666 neuron development	6	5.46e-01	-0.143000	0.896000
GO:0001837 epithelial to mesenchymal transition	15	3.42e-01	0.142000	0.856000
GO:0003755 peptidyl-prolyl cis-trans isomerase activity	7	5.16e-01	0.142000	0.894000
GO:0045663 positive regulation of myoblast differentiation	13	3.76e-01	0.142000	0.881000
GO:0030330 DNA damage response, signal transduction by p53 class mediator	6	5.47e-01	-0.142000	0.896000
GO:0070555 response to interleukin-1	6	5.47e-01	-0.142000	0.896000
GO:0032355 response to estradiol	13	3.77e-01	-0.142000	0.881000
GO:0042102 positive regulation of T cell proliferation	16	3.27e-01	-0.142000	0.854000
GO:0019731 antibacterial humoral response	8	4.88e-01	0.142000	0.894000
GO:0019933 cAMP-mediated signaling	6	5.48e-01	-0.142000	0.896000
GO:0004715 non-membrane spanning protein tyrosine kinase activity	16	3.28e-01	0.142000	0.854000
GO:0031100 animal organ regeneration	6	5.49e-01	0.142000	0.896000
GO:0008217 regulation of blood pressure	12	3.98e-01	0.142000	0.886000
GO:0043495 protein-membrane adaptor activity	9	4.64e-01	-0.141000	0.894000
GO:0001223 transcription coactivator binding	9	4.64e-01	0.141000	0.894000
GO:0042130 negative regulation of T cell proliferation	9	4.64e-01	0.141000	0.894000
GO:0071385 cellular response to glucocorticoid stimulus	8	4.90e-01	0.141000	0.894000
GO:0045765 regulation of angiogenesis	5	5.85e-01	-0.141000	0.917000
GO:0060816 random inactivation of X chromosome	7	5.20e-01	0.141000	0.894000
GO:0051292 nuclear pore complex assembly	5	5.86e-01	-0.141000	0.917000
GO:0030154 cell differentiation	50	8.97e-02	-0.140000	0.767000
GO:0034314 Arp2/3 complex-mediated actin nucleation	8	4.93e-01	-0.140000	0.894000
GO:0140857 histone H3T45 kinase activity	50	9.01e-02	0.140000	0.767000
GO:0034599 cellular response to oxidative stress	22	2.59e-01	0.140000	0.829000
GO:0005788 endoplasmic reticulum lumen	28	2.04e-01	-0.140000	0.783000
GO:0006091 generation of precursor metabolites and energy	9	4.70e-01	0.139000	0.894000
GO:0001774 microglial cell activation	10	4.47e-01	-0.139000	0.894000
GO:1901223 negative regulation of non-canonical NF-kappaB signal transduction	9	4.71e-01	-0.139000	0.894000
GO:0043124 negative regulation of canonical NF-kappaB signal transduction	19	2.97e-01	0.139000	0.837000
GO:0032092 positive regulation of protein binding	16	3.38e-01	0.139000	0.856000
GO:0035401 histone H3Y41 kinase activity	20	2.85e-01	0.139000	0.829000
GO:0140801 histone H2AXY142 kinase activity	20	2.85e-01	0.139000	0.829000
GO:0035994 response to muscle stretch	5	5.92e-01	0.139000	0.920000
GO:0005903 brush border	15	3.55e-01	0.138000	0.863000
GO:0051091 positive regulation of DNA-binding transcription factor activity	11	4.28e-01	0.138000	0.891000
GO:0006892 post-Golgi vesicle-mediated transport	6	5.58e-01	0.138000	0.903000
GO:0140678 molecular function inhibitor activity	8	5.03e-01	-0.137000	0.894000
GO:0045335 phagocytic vesicle	21	2.79e-01	-0.137000	0.829000
GO:0045444 fat cell differentiation	18	3.17e-01	-0.137000	0.850000
GO:0042147 retrograde transport, endosome to Golgi	13	3.95e-01	-0.137000	0.883000
GO:0001825 blastocyst formation	5	5.97e-01	0.137000	0.921000
GO:0051017 actin filament bundle assembly	7	5.32e-01	0.137000	0.894000
GO:0001578 microtubule bundle formation	5	5.99e-01	-0.136000	0.921000
GO:0031593 polyubiquitin modification-dependent protein binding	5	5.99e-01	-0.136000	0.921000
GO:0042307 positive regulation of protein import into nucleus	12	4.16e-01	0.136000	0.888000
GO:0035019 somatic stem cell population maintenance	9	4.81e-01	-0.136000	0.894000
GO:0005901 caveola	7	5.35e-01	0.136000	0.894000
GO:0006355 regulation of DNA-templated transcription	71	5.22e-02	0.136000	0.667000
GO:0001726 ruffle	24	2.54e-01	0.135000	0.829000
GO:0045666 positive regulation of neuron differentiation	7	5.37e-01	-0.135000	0.894000
GO:0009410 response to xenobiotic stimulus	35	1.71e-01	-0.135000	0.767000
GO:0008266 poly(U) RNA binding	7	5.38e-01	-0.135000	0.894000
GO:0032418 lysosome localization	5	6.03e-01	0.135000	0.922000
GO:0032981 mitochondrial respiratory chain complex I assembly	17	3.40e-01	0.134000	0.856000
GO:0030282 bone mineralization	5	6.04e-01	0.134000	0.922000
GO:0031902 late endosome membrane	31	2.00e-01	-0.134000	0.777000
GO:0030864 cortical actin cytoskeleton	11	4.43e-01	0.134000	0.894000
GO:0070821 tertiary granule membrane	23	2.69e-01	-0.134000	0.829000
GO:0050804 modulation of chemical synaptic transmission	11	4.45e-01	0.133000	0.894000
GO:0006397 mRNA processing	43	1.35e-01	0.133000	0.767000
GO:0016485 protein processing	6	5.73e-01	0.133000	0.909000
GO:0060261 positive regulation of transcription initiation by RNA polymerase II	7	5.43e-01	0.133000	0.894000
GO:0031122 cytoplasmic microtubule organization	10	4.68e-01	-0.133000	0.894000
GO:0045739 positive regulation of DNA repair	6	5.74e-01	-0.133000	0.909000
GO:0048018 receptor ligand activity	9	4.92e-01	0.133000	0.894000
GO:0034704 calcium channel complex	6	5.75e-01	0.133000	0.909000
GO:0046777 protein autophosphorylation	26	2.45e-01	0.133000	0.829000
GO:0090090 negative regulation of canonical Wnt signaling pathway	17	3.46e-01	-0.133000	0.860000
GO:0055088 lipid homeostasis	5	6.09e-01	-0.132000	0.922000
GO:0007010 cytoskeleton organization	19	3.20e-01	0.132000	0.851000
GO:0007259 cell surface receptor signaling pathway via JAK-STAT	9	4.93e-01	-0.132000	0.894000
GO:0043536 positive regulation of blood vessel endothelial cell migration	12	4.30e-01	0.132000	0.891000
GO:0042110 T cell activation	18	3.35e-01	0.132000	0.855000
GO:0003727 single-stranded RNA binding	9	4.95e-01	-0.132000	0.894000
GO:0010592 positive regulation of lamellipodium assembly	11	4.51e-01	0.132000	0.894000
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	10	4.72e-01	0.132000	0.894000
GO:0008017 microtubule binding	33	1.95e-01	-0.132000	0.771000
GO:0045724 positive regulation of cilium assembly	5	6.11e-01	0.132000	0.922000
GO:0045214 sarcomere organization	5	6.12e-01	0.131000	0.922000
GO:0060333 type II interferon-mediated signaling pathway	9	4.97e-01	-0.131000	0.894000
GO:0042605 peptide antigen binding	16	3.67e-01	-0.131000	0.871000
GO:0043113 receptor clustering	5	6.15e-01	0.130000	0.922000
GO:0043407 negative regulation of MAP kinase activity	8	5.25e-01	-0.130000	0.894000
GO:0004676 3-phosphoinositide-dependent protein kinase activity	49	1.21e-01	0.130000	0.767000
GO:0004677 DNA-dependent protein kinase activity	49	1.21e-01	0.130000	0.767000
GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity	49	1.21e-01	0.130000	0.767000
GO:0004711 ribosomal protein S6 kinase activity	49	1.21e-01	0.130000	0.767000
GO:0035175 histone H3S10 kinase activity	49	1.21e-01	0.130000	0.767000
GO:0035979 histone H2AXS139 kinase activity	49	1.21e-01	0.130000	0.767000
GO:0044022 histone H3S28 kinase activity	49	1.21e-01	0.130000	0.767000
GO:0044023 histone H4S1 kinase activity	49	1.21e-01	0.130000	0.767000
GO:0044024 histone H2AS1 kinase activity	49	1.21e-01	0.130000	0.767000
GO:0044025 histone H2BS14 kinase activity	49	1.21e-01	0.130000	0.767000
GO:0072354 histone H3T3 kinase activity	49	1.21e-01	0.130000	0.767000
GO:0072371 histone H2AS121 kinase activity	49	1.21e-01	0.130000	0.767000
GO:0072518 Rho-dependent protein serine/threonine kinase activity	49	1.21e-01	0.130000	0.767000
GO:0140823 histone H2BS36 kinase activity	49	1.21e-01	0.130000	0.767000
GO:0140855 histone H3S57 kinase activity	49	1.21e-01	0.130000	0.767000
GO:1990244 histone H2AT120 kinase activity	49	1.21e-01	0.130000	0.767000
GO:2001056 positive regulation of cysteine-type endopeptidase activity	13	4.20e-01	-0.130000	0.891000
GO:0006364 rRNA processing	22	2.97e-01	-0.129000	0.837000
GO:0008094 ATP-dependent activity, acting on DNA	8	5.28e-01	0.129000	0.894000
GO:0043014 alpha-tubulin binding	10	4.82e-01	0.129000	0.894000
GO:0001756 somitogenesis	8	5.30e-01	0.129000	0.894000
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation	14	4.07e-01	0.129000	0.886000
GO:0005730 nucleolus	163	6.77e-03	-0.128000	0.411000
GO:0050832 defense response to fungus	8	5.31e-01	-0.128000	0.894000
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific	28	2.44e-01	0.128000	0.829000
GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction	11	4.64e-01	-0.128000	0.894000
GO:0001570 vasculogenesis	7	5.59e-01	0.128000	0.903000
GO:0035259 nuclear glucocorticoid receptor binding	8	5.33e-01	-0.128000	0.894000
GO:0017134 fibroblast growth factor binding	5	6.22e-01	-0.128000	0.922000
GO:0005813 centrosome	96	3.50e-02	0.128000	0.626000
GO:0021772 olfactory bulb development	6	5.90e-01	-0.127000	0.919000
GO:0097060 synaptic membrane	5	6.24e-01	0.127000	0.922000
GO:0005905 clathrin-coated pit	16	3.82e-01	0.127000	0.881000
GO:0090263 positive regulation of canonical Wnt signaling pathway	26	2.67e-01	-0.127000	0.829000
GO:0097190 apoptotic signaling pathway	9	5.13e-01	-0.126000	0.894000
GO:0001934 positive regulation of protein phosphorylation	22	3.08e-01	-0.126000	0.841000
GO:0003724 RNA helicase activity	11	4.70e-01	-0.126000	0.894000
GO:0032469 endoplasmic reticulum calcium ion homeostasis	6	5.94e-01	0.126000	0.921000
GO:0010507 negative regulation of autophagy	10	4.92e-01	0.126000	0.894000
GO:0043524 negative regulation of neuron apoptotic process	25	2.84e-01	-0.125000	0.829000
GO:0051090 regulation of DNA-binding transcription factor activity	6	5.98e-01	0.125000	0.921000
GO:0002092 positive regulation of receptor internalization	6	5.99e-01	0.124000	0.921000
GO:0046827 positive regulation of protein export from nucleus	6	5.99e-01	-0.124000	0.921000
GO:0048538 thymus development	10	4.98e-01	0.124000	0.894000
GO:0031519 PcG protein complex	5	6.31e-01	0.124000	0.923000
GO:0033138 positive regulation of peptidyl-serine phosphorylation	9	5.20e-01	-0.124000	0.894000
GO:0046718 symbiont entry into host cell	22	3.17e-01	0.124000	0.850000
GO:0006357 regulation of transcription by RNA polymerase II	168	7.91e-03	0.124000	0.434000
GO:0006376 mRNA splice site recognition	11	4.80e-01	0.124000	0.894000
GO:0009612 response to mechanical stimulus	10	5.01e-01	-0.123000	0.894000
GO:0048306 calcium-dependent protein binding	19	3.55e-01	-0.123000	0.863000
GO:0042273 ribosomal large subunit biogenesis	9	5.26e-01	-0.123000	0.894000
GO:0048025 negative regulation of mRNA splicing, via spliceosome	9	5.26e-01	-0.123000	0.894000
GO:0071108 protein K48-linked deubiquitination	5	6.36e-01	-0.123000	0.926000
GO:0012506 vesicle membrane	8	5.51e-01	-0.122000	0.897000
GO:0048661 positive regulation of smooth muscle cell proliferation	8	5.51e-01	0.122000	0.897000
GO:0008285 negative regulation of cell population proliferation	55	1.23e-01	-0.122000	0.767000
GO:1901796 regulation of signal transduction by p53 class mediator	9	5.28e-01	-0.122000	0.894000
GO:0045893 positive regulation of DNA-templated transcription	128	2.13e-02	0.122000	0.594000
GO:0035402 histone H3T11 kinase activity	51	1.39e-01	0.121000	0.767000
GO:0006805 xenobiotic metabolic process	6	6.08e-01	-0.121000	0.922000
GO:0061744 motor behavior	6	6.08e-01	0.121000	0.922000
GO:0070063 RNA polymerase binding	7	5.80e-01	0.121000	0.913000
GO:0035403 histone H3T6 kinase activity	50	1.44e-01	0.121000	0.767000
GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity	5	6.41e-01	0.121000	0.926000
GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	5	6.41e-01	0.121000	0.926000
GO:0030889 negative regulation of B cell proliferation	7	5.81e-01	0.121000	0.913000
GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process	5	6.41e-01	0.121000	0.926000
GO:0016605 PML body	25	3.02e-01	-0.120000	0.841000
GO:0009791 post-embryonic development	11	4.92e-01	-0.120000	0.894000
GO:0000287 magnesium ion binding	29	2.68e-01	-0.120000	0.829000
GO:0005794 Golgi apparatus	145	1.65e-02	0.120000	0.554000
GO:0070034 telomerase RNA binding	6	6.13e-01	-0.120000	0.922000
GO:0014069 postsynaptic density	45	1.71e-01	-0.119000	0.767000
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	6	6.14e-01	-0.119000	0.922000
GO:0034399 nuclear periphery	5	6.46e-01	-0.119000	0.926000
GO:0004679 AMP-activated protein kinase activity	50	1.51e-01	0.119000	0.767000
GO:0004721 phosphoprotein phosphatase activity	8	5.62e-01	0.119000	0.903000
GO:0051879 Hsp90 protein binding	7	5.87e-01	0.119000	0.917000
GO:0071356 cellular response to tumor necrosis factor	28	2.81e-01	-0.119000	0.829000
GO:0045271 respiratory chain complex I	20	3.61e-01	0.119000	0.866000
GO:0006959 humoral immune response	9	5.40e-01	-0.118000	0.894000
GO:0035064 methylated histone binding	8	5.64e-01	0.118000	0.904000
GO:0000209 protein polyubiquitination	35	2.31e-01	-0.118000	0.826000
GO:0019905 syntaxin binding	7	5.90e-01	-0.118000	0.919000
GO:0001701 in utero embryonic development	27	2.93e-01	0.118000	0.835000
GO:0008305 integrin complex	7	5.91e-01	0.117000	0.920000
GO:0038187 pattern recognition receptor activity	6	6.19e-01	-0.117000	0.922000
GO:0005615 extracellular space	148	1.76e-02	-0.117000	0.554000
GO:0032508 DNA duplex unwinding	11	5.02e-01	-0.117000	0.894000
GO:0071889 14-3-3 protein binding	11	5.02e-01	0.117000	0.894000
GO:0007420 brain development	15	4.34e-01	0.117000	0.893000
GO:2000379 positive regulation of reactive oxygen species metabolic process	10	5.22e-01	0.117000	0.894000
GO:0098553 lumenal side of endoplasmic reticulum membrane	18	3.94e-01	-0.117000	0.883000
GO:0034976 response to endoplasmic reticulum stress	21	3.60e-01	-0.116000	0.866000
GO:0031333 negative regulation of protein-containing complex assembly	10	5.27e-01	0.116000	0.894000
GO:0042593 glucose homeostasis	9	5.49e-01	-0.116000	0.896000
GO:0050766 positive regulation of phagocytosis	14	4.56e-01	-0.116000	0.894000
GO:0016079 synaptic vesicle exocytosis	5	6.55e-01	-0.115000	0.926000
GO:0097150 neuronal stem cell population maintenance	5	6.55e-01	-0.115000	0.926000
GO:0007613 memory	8	5.74e-01	-0.115000	0.909000
GO:0045766 positive regulation of angiogenesis	29	2.87e-01	-0.115000	0.829000
GO:0099524 postsynaptic cytosol	7	5.99e-01	-0.115000	0.921000
GO:0016525 negative regulation of angiogenesis	16	4.28e-01	0.115000	0.891000
GO:2000377 regulation of reactive oxygen species metabolic process	6	6.27e-01	-0.115000	0.922000
GO:0002027 regulation of heart rate	5	6.58e-01	0.115000	0.926000
GO:1903077 negative regulation of protein localization to plasma membrane	9	5.53e-01	0.114000	0.899000
GO:0032259 methylation	8	5.76e-01	0.114000	0.909000
GO:0008233 peptidase activity	11	5.13e-01	-0.114000	0.894000
GO:0044389 ubiquitin-like protein ligase binding	6	6.29e-01	0.114000	0.923000
GO:0045651 positive regulation of macrophage differentiation	5	6.60e-01	-0.114000	0.926000
GO:0032993 protein-DNA complex	14	4.65e-01	0.113000	0.894000
GO:0048471 perinuclear region of cytoplasm	126	3.37e-02	0.113000	0.623000
GO:0098869 cellular oxidant detoxification	9	5.59e-01	0.113000	0.903000
GO:0070588 calcium ion transmembrane transport	10	5.39e-01	-0.113000	0.894000
GO:0061630 ubiquitin protein ligase activity	50	1.75e-01	0.112000	0.767000
GO:0030317 flagellated sperm motility	5	6.64e-01	0.112000	0.928000
GO:0060828 regulation of canonical Wnt signaling pathway	5	6.65e-01	0.112000	0.928000
GO:0030295 protein kinase activator activity	9	5.62e-01	-0.112000	0.903000
GO:0017148 negative regulation of translation	25	3.36e-01	-0.112000	0.855000
GO:0010586 miRNA metabolic process	5	6.67e-01	-0.111000	0.928000
GO:0043627 response to estrogen	5	6.67e-01	-0.111000	0.928000
GO:0046326 positive regulation of D-glucose import	6	6.38e-01	-0.111000	0.926000
GO:0045047 protein targeting to ER	6	6.38e-01	0.111000	0.926000
GO:0001947 heart looping	5	6.68e-01	0.111000	0.928000
GO:0050776 regulation of immune response	8	5.88e-01	0.111000	0.918000
GO:0001725 stress fiber	17	4.32e-01	0.111000	0.893000
GO:0006260 DNA replication	7	6.13e-01	-0.111000	0.922000
GO:0008083 growth factor activity	7	6.13e-01	-0.111000	0.922000
GO:0008104 protein localization	26	3.33e-01	-0.111000	0.855000
GO:0045665 negative regulation of neuron differentiation	6	6.40e-01	0.110000	0.926000
GO:0006406 mRNA export from nucleus	13	4.93e-01	-0.110000	0.894000
GO:0051496 positive regulation of stress fiber assembly	11	5.28e-01	0.110000	0.894000
GO:0030159 signaling receptor complex adaptor activity	6	6.41e-01	0.110000	0.926000
GO:0006123 mitochondrial electron transport, cytochrome c to oxygen	15	4.64e-01	-0.110000	0.894000
GO:0045277 respiratory chain complex IV	15	4.64e-01	-0.110000	0.894000
GO:0034333 adherens junction assembly	5	6.72e-01	0.110000	0.930000
GO:0008542 visual learning	7	6.16e-01	-0.110000	0.922000
GO:0140507 granzyme-mediated programmed cell death signaling pathway	6	6.43e-01	0.110000	0.926000
GO:0042608 T cell receptor binding	5	6.72e-01	-0.109000	0.930000
GO:0043274 phospholipase binding	5	6.72e-01	0.109000	0.930000
GO:0016567 protein ubiquitination	55	1.67e-01	0.109000	0.767000
GO:0070542 response to fatty acid	5	6.73e-01	-0.109000	0.930000
GO:0006914 autophagy	32	2.90e-01	-0.109000	0.831000
GO:0006338 chromatin remodeling	169	1.97e-02	0.109000	0.588000
GO:0005262 calcium channel activity	7	6.20e-01	-0.108000	0.922000
GO:0005839 proteasome core complex	9	5.75e-01	-0.108000	0.909000
GO:0007265 Ras protein signal transduction	18	4.29e-01	-0.108000	0.891000
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process	56	1.69e-01	0.108000	0.767000
GO:2000779 regulation of double-strand break repair	6	6.49e-01	0.107000	0.926000
GO:0003743 translation initiation factor activity	19	4.20e-01	0.107000	0.891000
GO:0004197 cysteine-type endopeptidase activity	19	4.21e-01	-0.107000	0.891000
GO:0000502 proteasome complex	13	5.07e-01	-0.107000	0.894000
GO:0008344 adult locomotory behavior	10	5.60e-01	0.107000	0.903000
GO:0071013 catalytic step 2 spliceosome	23	3.79e-01	-0.107000	0.881000
GO:0015031 protein transport	57	1.70e-01	-0.107000	0.767000
GO:0015986 proton motive force-driven ATP synthesis	15	4.77e-01	-0.107000	0.894000
GO:0004435 phosphatidylinositol phospholipase C activity	5	6.81e-01	0.106000	0.936000
GO:0007097 nuclear migration	6	6.54e-01	0.106000	0.926000
GO:0000375 RNA splicing, via transesterification reactions	6	6.54e-01	0.106000	0.926000
GO:0035579 specific granule membrane	28	3.37e-01	-0.106000	0.856000
GO:1990090 cellular response to nerve growth factor stimulus	12	5.28e-01	-0.106000	0.894000
GO:0071526 semaphorin-plexin signaling pathway	7	6.30e-01	0.106000	0.923000
GO:0030316 osteoclast differentiation	12	5.29e-01	0.105000	0.894000
GO:0140297 DNA-binding transcription factor binding	36	2.79e-01	-0.105000	0.829000
GO:0006396 RNA processing	21	4.06e-01	0.105000	0.886000
GO:0006366 transcription by RNA polymerase II	40	2.55e-01	-0.105000	0.829000
GO:0005783 endoplasmic reticulum	164	2.64e-02	-0.105000	0.594000
GO:0005874 microtubule	36	2.82e-01	-0.105000	0.829000
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading	15	4.85e-01	0.105000	0.894000
GO:0097191 extrinsic apoptotic signaling pathway	15	4.85e-01	-0.105000	0.894000
GO:0065003 protein-containing complex assembly	27	3.51e-01	0.104000	0.863000
GO:0036503 ERAD pathway	10	5.70e-01	0.104000	0.909000
GO:1904263 positive regulation of TORC1 signaling	14	5.02e-01	0.104000	0.894000
GO:0050673 epithelial cell proliferation	7	6.34e-01	-0.104000	0.925000
GO:0016477 cell migration	36	2.85e-01	0.104000	0.829000
GO:0033120 positive regulation of RNA splicing	6	6.60e-01	0.104000	0.926000
GO:1900246 positive regulation of RIG-I signaling pathway	5	6.90e-01	-0.103000	0.938000
GO:0005198 structural molecule activity	14	5.05e-01	0.103000	0.894000
GO:0043488 regulation of mRNA stability	12	5.38e-01	0.103000	0.894000
GO:0031397 negative regulation of protein ubiquitination	16	4.78e-01	0.103000	0.894000
GO:0001933 negative regulation of protein phosphorylation	10	5.74e-01	-0.103000	0.909000
GO:0000724 double-strand break repair via homologous recombination	13	5.22e-01	0.103000	0.894000
GO:0005777 peroxisome	10	5.77e-01	0.102000	0.909000
GO:0043392 negative regulation of DNA binding	6	6.65e-01	0.102000	0.928000
GO:0006911 phagocytosis, engulfment	8	6.17e-01	0.102000	0.922000
GO:0045445 myoblast differentiation	7	6.41e-01	-0.102000	0.926000
GO:0098609 cell-cell adhesion	27	3.62e-01	-0.102000	0.866000
GO:0060765 regulation of androgen receptor signaling pathway	6	6.66e-01	-0.102000	0.928000
GO:0001784 phosphotyrosine residue binding	14	5.11e-01	0.102000	0.894000
GO:0071222 cellular response to lipopolysaccharide	37	2.92e-01	-0.101000	0.831000
GO:0017053 transcription repressor complex	20	4.36e-01	0.101000	0.893000
GO:0070536 protein K63-linked deubiquitination	7	6.44e-01	0.101000	0.926000
GO:0012505 endomembrane system	14	5.15e-01	-0.101000	0.894000
GO:0090575 RNA polymerase II transcription regulator complex	32	3.27e-01	0.101000	0.854000
GO:0005518 collagen binding	8	6.23e-01	0.101000	0.922000
GO:0031410 cytoplasmic vesicle	46	2.44e-01	0.100000	0.829000
GO:0030145 manganese ion binding	8	6.24e-01	-0.100000	0.922000
GO:0042542 response to hydrogen peroxide	11	5.66e-01	0.100000	0.905000
GO:0097225 sperm midpiece	8	6.26e-01	-0.099700	0.922000
GO:0031954 positive regulation of protein autophosphorylation	5	7.00e-01	0.099600	0.940000
GO:0032012 regulation of ARF protein signal transduction	5	7.00e-01	0.099600	0.940000
GO:0043320 natural killer cell degranulation	5	7.01e-01	-0.099200	0.940000
GO:2000114 regulation of establishment of cell polarity	6	6.75e-01	0.099000	0.930000
GO:1904646 cellular response to amyloid-beta	13	5.39e-01	-0.098800	0.894000
GO:0030027 lamellipodium	38	2.98e-01	0.098600	0.837000
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment	9	6.10e-01	-0.098500	0.922000
GO:0016601 Rac protein signal transduction	8	6.30e-01	0.098500	0.923000
GO:0071364 cellular response to epidermal growth factor stimulus	11	5.75e-01	-0.098000	0.909000
GO:0071347 cellular response to interleukin-1	13	5.42e-01	-0.098000	0.894000
GO:0005686 U2 snRNP	7	6.55e-01	-0.097900	0.926000
GO:0009749 response to glucose	7	6.55e-01	-0.097900	0.926000
GO:0051607 defense response to virus	42	2.80e-01	0.097400	0.829000
GO:0051959 dynein light intermediate chain binding	7	6.57e-01	-0.097300	0.926000
GO:0031463 Cul3-RING ubiquitin ligase complex	5	7.08e-01	0.097100	0.942000
GO:0045087 innate immune response	80	1.42e-01	-0.096900	0.767000
GO:0032880 regulation of protein localization	15	5.18e-01	-0.096900	0.894000
GO:0016055 Wnt signaling pathway	23	4.25e-01	0.096700	0.891000
GO:0006811 monoatomic ion transport	6	6.83e-01	0.096500	0.937000
GO:1902600 proton transmembrane transport	55	2.22e-01	-0.096500	0.809000
GO:0070301 cellular response to hydrogen peroxide	10	5.99e-01	-0.096400	0.921000
GO:0032088 negative regulation of NF-kappaB transcription factor activity	15	5.20e-01	0.096300	0.894000
GO:0006417 regulation of translation	16	5.07e-01	-0.096300	0.894000
GO:0032715 negative regulation of interleukin-6 production	9	6.18e-01	-0.096200	0.922000
GO:0030496 midbody	33	3.43e-01	-0.096100	0.856000
GO:0004725 protein tyrosine phosphatase activity	14	5.36e-01	-0.095900	0.894000
GO:0051117 ATPase binding	12	5.67e-01	-0.095700	0.907000
GO:0097250 mitochondrial respirasome assembly	5	7.12e-01	-0.095600	0.944000
GO:0030017 sarcomere	10	6.03e-01	0.095300	0.922000
GO:0006473 protein acetylation	5	7.13e-01	-0.095100	0.944000
GO:0005856 cytoskeleton	72	1.71e-01	0.095000	0.767000
GO:0098803 respiratory chain complex	6	6.88e-01	0.094900	0.938000
GO:0006405 RNA export from nucleus	6	6.89e-01	-0.094600	0.938000
GO:0098794 postsynapse	36	3.31e-01	0.094500	0.855000
GO:0051497 negative regulation of stress fiber assembly	8	6.46e-01	0.094100	0.926000
GO:0005544 calcium-dependent phospholipid binding	9	6.26e-01	-0.094000	0.922000
GO:0030866 cortical actin cytoskeleton organization	10	6.08e-01	-0.093900	0.922000
GO:0023026 MHC class II protein complex binding	16	5.19e-01	-0.093600	0.894000
GO:0032731 positive regulation of interleukin-1 beta production	16	5.19e-01	0.093600	0.894000
GO:0030036 actin cytoskeleton organization	46	2.78e-01	0.093500	0.829000
GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)	8	6.49e-01	-0.093100	0.926000
GO:0071346 cellular response to type II interferon	21	4.63e-01	-0.093100	0.894000
GO:0005516 calmodulin binding	30	3.82e-01	0.093000	0.881000
GO:0030522 intracellular receptor signaling pathway	5	7.19e-01	-0.093000	0.944000
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator	6	6.95e-01	-0.092600	0.940000
GO:0003697 single-stranded DNA binding	21	4.67e-01	-0.092200	0.894000
GO:0030490 maturation of SSU-rRNA	5	7.22e-01	-0.092100	0.944000
GO:0010759 positive regulation of macrophage chemotaxis	5	7.22e-01	0.091900	0.944000
GO:0042393 histone binding	39	3.26e-01	0.091900	0.854000
GO:0009898 cytoplasmic side of plasma membrane	29	3.96e-01	0.091800	0.884000
GO:0001221 transcription coregulator binding	12	5.83e-01	-0.091700	0.915000
GO:0006631 fatty acid metabolic process	8	6.55e-01	0.091500	0.926000
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	10	6.18e-01	-0.091300	0.922000
GO:0098686 hippocampal mossy fiber to CA3 synapse	8	6.56e-01	0.091200	0.926000
GO:0006468 protein phosphorylation	73	1.87e-01	0.090900	0.767000
GO:0005789 endoplasmic reticulum membrane	108	1.12e-01	-0.090900	0.767000
GO:0000723 telomere maintenance	8	6.57e-01	0.090800	0.926000
GO:0140467 integrated stress response signaling	8	6.57e-01	0.090800	0.926000
GO:0030670 phagocytic vesicle membrane	29	4.01e-01	-0.090800	0.886000
GO:0043066 negative regulation of apoptotic process	89	1.48e-01	-0.090800	0.767000
GO:0045333 cellular respiration	20	4.86e-01	-0.090500	0.894000
GO:0055037 recycling endosome	20	4.88e-01	0.090100	0.894000
GO:0008076 voltage-gated potassium channel complex	6	7.03e-01	0.090100	0.940000
GO:0019941 modification-dependent protein catabolic process	6	7.03e-01	0.089900	0.940000
GO:0004674 protein serine/threonine kinase activity	74	1.90e-01	0.089700	0.767000
GO:0071353 cellular response to interleukin-4	6	7.05e-01	-0.089600	0.940000
GO:0048008 platelet-derived growth factor receptor signaling pathway	6	7.05e-01	-0.089400	0.940000
GO:0004252 serine-type endopeptidase activity	10	6.26e-01	-0.089300	0.922000
GO:0005576 extracellular region	175	5.23e-02	-0.089000	0.667000
GO:0098685 Schaffer collateral - CA1 synapse	16	5.43e-01	0.088300	0.894000
GO:0006413 translational initiation	24	4.57e-01	0.088200	0.894000
GO:0006661 phosphatidylinositol biosynthetic process	7	6.88e-01	-0.087800	0.938000
GO:0010800 positive regulation of peptidyl-threonine phosphorylation	8	6.68e-01	0.087800	0.928000
GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction	5	7.35e-01	0.087600	0.950000
GO:0004879 nuclear receptor activity	6	7.11e-01	0.087600	0.944000
GO:0051602 response to electrical stimulus	9	6.50e-01	-0.087500	0.926000
GO:0005080 protein kinase C binding	14	5.72e-01	-0.087500	0.909000
GO:0007264 small GTPase-mediated signal transduction	19	5.12e-01	0.087400	0.894000
GO:0043922 negative regulation by host of viral transcription	5	7.36e-01	0.087200	0.951000
GO:0032729 positive regulation of type II interferon production	13	5.88e-01	-0.087000	0.918000
GO:0016236 macroautophagy	15	5.62e-01	-0.086700	0.903000
GO:0070374 positive regulation of ERK1 and ERK2 cascade	25	4.56e-01	-0.086700	0.894000
GO:0033173 calcineurin-NFAT signaling cascade	6	7.15e-01	-0.086400	0.944000
GO:0050860 negative regulation of T cell receptor signaling pathway	9	6.57e-01	-0.085700	0.926000
GO:0007059 chromosome segregation	11	6.24e-01	-0.085600	0.922000
GO:0000922 spindle pole	18	5.32e-01	0.085500	0.894000
GO:0003714 transcription corepressor activity	48	3.12e-01	0.085400	0.844000
GO:0035633 maintenance of blood-brain barrier	6	7.18e-01	0.085300	0.944000
GO:0000226 microtubule cytoskeleton organization	20	5.12e-01	0.085200	0.894000
GO:0045089 positive regulation of innate immune response	7	6.97e-01	0.085200	0.940000
GO:0000118 histone deacetylase complex	11	6.26e-01	-0.085200	0.922000
GO:0044548 S100 protein binding	7	6.99e-01	0.084700	0.940000
GO:0000785 chromatin	143	9.26e-02	0.084500	0.767000
GO:0032481 positive regulation of type I interferon production	12	6.14e-01	0.084500	0.922000
GO:0099175 regulation of postsynapse organization	5	7.45e-01	-0.084200	0.953000
GO:0060079 excitatory postsynaptic potential	7	7.01e-01	-0.084100	0.940000
GO:0005811 lipid droplet	13	6.01e-01	-0.084000	0.922000
GO:0032452 histone demethylase activity	8	6.82e-01	0.084000	0.936000
GO:0010975 regulation of neuron projection development	6	7.24e-01	0.083500	0.944000
GO:1905168 positive regulation of double-strand break repair via homologous recombination	10	6.49e-01	0.083500	0.926000
GO:0007015 actin filament organization	23	4.91e-01	0.083500	0.894000
GO:0046332 SMAD binding	13	6.06e-01	0.082900	0.922000
GO:0009617 response to bacterium	8	6.86e-01	0.082800	0.938000
GO:0020037 heme binding	8	6.86e-01	-0.082700	0.938000
GO:0051092 positive regulation of NF-kappaB transcription factor activity	31	4.34e-01	-0.081800	0.893000
GO:0048511 rhythmic process	12	6.26e-01	0.081600	0.922000
GO:0046872 metal ion binding	214	5.19e-02	0.081500	0.667000
GO:0005741 mitochondrial outer membrane	33	4.22e-01	-0.081500	0.891000
GO:1990830 cellular response to leukemia inhibitory factor	18	5.52e-01	0.081500	0.897000
GO:0007596 blood coagulation	13	6.13e-01	0.081400	0.922000
GO:0010008 endosome membrane	48	3.35e-01	-0.081400	0.855000
GO:0051015 actin filament binding	42	3.68e-01	0.081200	0.871000
GO:0051225 spindle assembly	8	6.92e-01	0.081200	0.939000
GO:0008021 synaptic vesicle	13	6.18e-01	0.080100	0.922000
GO:0008047 enzyme activator activity	13	6.19e-01	-0.080000	0.922000
GO:0009060 aerobic respiration	25	4.92e-01	0.079900	0.894000
GO:0019076 viral release from host cell	5	7.58e-01	-0.079700	0.956000
GO:0008283 cell population proliferation	20	5.39e-01	0.079700	0.894000
GO:0032456 endocytic recycling	11	6.50e-01	0.079300	0.926000
GO:0005815 microtubule organizing center	12	6.37e-01	0.078900	0.926000
GO:0003723 RNA binding	381	1.73e-02	-0.078900	0.554000
GO:0005507 copper ion binding	7	7.19e-01	0.078700	0.944000
GO:0006120 mitochondrial electron transport, NADH to ubiquinone	17	5.76e-01	0.078700	0.909000
GO:0031466 Cul5-RING ubiquitin ligase complex	6	7.39e-01	0.078700	0.951000
GO:0030133 transport vesicle	10	6.68e-01	-0.078600	0.928000
GO:0010494 cytoplasmic stress granule	27	4.83e-01	0.078600	0.894000
GO:0045202 synapse	81	2.31e-01	-0.078500	0.826000
GO:0071320 cellular response to cAMP	10	6.70e-01	-0.078100	0.930000
GO:0016251 RNA polymerase II general transcription initiation factor activity	5	7.63e-01	-0.078000	0.959000
GO:0045648 positive regulation of erythrocyte differentiation	11	6.57e-01	0.077500	0.926000
GO:0030183 B cell differentiation	22	5.32e-01	0.077500	0.894000
GO:0005765 lysosomal membrane	70	2.71e-01	-0.077500	0.829000
GO:0032212 positive regulation of telomere maintenance via telomerase	10	6.72e-01	0.077500	0.930000
GO:0000956 nuclear-transcribed mRNA catabolic process	6	7.44e-01	-0.077300	0.953000
GO:0005881 cytoplasmic microtubule	12	6.44e-01	-0.077200	0.926000
GO:0030865 cortical cytoskeleton organization	5	7.66e-01	0.077200	0.960000
GO:0002040 sprouting angiogenesis	5	7.66e-01	0.076900	0.960000
GO:0061077 chaperone-mediated protein folding	7	7.25e-01	0.076900	0.944000
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding	29	4.77e-01	0.076800	0.894000
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding	94	2.09e-01	0.076800	0.787000
GO:0006898 receptor-mediated endocytosis	15	6.09e-01	0.076700	0.922000
GO:0006886 intracellular protein transport	32	4.57e-01	0.076600	0.894000
GO:0002437 inflammatory response to antigenic stimulus	6	7.46e-01	0.076600	0.953000
GO:0019221 cytokine-mediated signaling pathway	22	5.37e-01	-0.076400	0.894000
GO:0002244 hematopoietic progenitor cell differentiation	12	6.48e-01	0.076400	0.926000
GO:0001764 neuron migration	21	5.48e-01	0.076200	0.896000
GO:0032760 positive regulation of tumor necrosis factor production	34	4.46e-01	-0.076200	0.894000
GO:0045088 regulation of innate immune response	7	7.28e-01	0.076000	0.946000
GO:0021766 hippocampus development	8	7.11e-01	-0.076000	0.944000
GO:0010629 negative regulation of gene expression	53	3.46e-01	-0.075900	0.860000
GO:0006913 nucleocytoplasmic transport	9	6.94e-01	-0.075800	0.940000
GO:0007605 sensory perception of sound	11	6.64e-01	0.075800	0.928000
GO:0005525 GTP binding	50	3.61e-01	-0.075700	0.866000
GO:0006986 response to unfolded protein	11	6.66e-01	0.075400	0.928000
GO:0032991 protein-containing complex	131	1.50e-01	0.075300	0.767000
GO:0010506 regulation of autophagy	14	6.28e-01	-0.075100	0.922000
GO:0071407 cellular response to organic cyclic compound	5	7.72e-01	0.075000	0.960000
GO:0042288 MHC class I protein binding	7	7.33e-01	-0.074800	0.950000
GO:0030218 erythrocyte differentiation	13	6.42e-01	-0.074700	0.926000
GO:0030018 Z disc	18	5.86e-01	0.074500	0.917000
GO:0008380 RNA splicing	42	4.09e-01	0.074400	0.886000
GO:0061621 canonical glycolysis	5	7.74e-01	0.074400	0.960000
GO:0031663 lipopolysaccharide-mediated signaling pathway	14	6.31e-01	0.074300	0.923000
GO:0000165 MAPK cascade	36	4.46e-01	-0.074000	0.894000
GO:0000049 tRNA binding	5	7.75e-01	-0.073900	0.960000
GO:0007160 cell-matrix adhesion	21	5.60e-01	-0.073800	0.903000
GO:0006486 protein glycosylation	9	7.03e-01	-0.073600	0.940000
GO:0044344 cellular response to fibroblast growth factor stimulus	7	7.37e-01	-0.073400	0.951000
GO:0045600 positive regulation of fat cell differentiation	9	7.04e-01	0.073300	0.940000
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	16	6.13e-01	0.073300	0.922000
GO:0050853 B cell receptor signaling pathway	22	5.54e-01	0.073200	0.900000
GO:0045599 negative regulation of fat cell differentiation	9	7.04e-01	-0.073200	0.940000
GO:0000122 negative regulation of transcription by RNA polymerase II	155	1.32e-01	0.073000	0.767000
GO:0007612 learning	6	7.57e-01	0.073000	0.956000
GO:0042981 regulation of apoptotic process	39	4.37e-01	-0.072700	0.893000
GO:0071539 protein localization to centrosome	5	7.79e-01	0.072700	0.960000
GO:0010718 positive regulation of epithelial to mesenchymal transition	7	7.40e-01	-0.072600	0.951000
GO:0030220 platelet formation	10	6.92e-01	-0.072500	0.939000
GO:0042594 response to starvation	6	7.59e-01	-0.072400	0.956000
GO:0030097 hemopoiesis	10	6.93e-01	0.072400	0.939000
GO:0030276 clathrin binding	8	7.24e-01	-0.072300	0.944000
GO:0006281 DNA repair	27	5.19e-01	0.072200	0.894000
GO:0035855 megakaryocyte development	9	7.09e-01	0.072100	0.943000
GO:0046982 protein heterodimerization activity	44	4.13e-01	0.072100	0.886000
GO:1990837 sequence-specific double-stranded DNA binding	44	4.14e-01	0.072000	0.886000
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	6	7.61e-01	0.071900	0.958000
GO:0021987 cerebral cortex development	14	6.43e-01	0.071800	0.926000
GO:0021762 substantia nigra development	14	6.48e-01	-0.070700	0.926000
GO:0060340 positive regulation of type I interferon-mediated signaling pathway	5	7.85e-01	0.070700	0.960000
GO:0042113 B cell activation	10	7.00e-01	-0.070500	0.940000
GO:0032007 negative regulation of TOR signaling	6	7.65e-01	-0.070500	0.960000
GO:0043525 positive regulation of neuron apoptotic process	16	6.27e-01	-0.070400	0.922000
GO:0017124 SH3 domain binding	30	5.09e-01	-0.070100	0.894000
GO:0003924 GTPase activity	51	3.93e-01	-0.070100	0.883000
GO:0061028 establishment of endothelial barrier	10	7.02e-01	-0.070100	0.940000
GO:0071549 cellular response to dexamethasone stimulus	9	7.17e-01	-0.070000	0.944000
GO:0000086 G2/M transition of mitotic cell cycle	8	7.34e-01	0.069500	0.950000
GO:0019005 SCF ubiquitin ligase complex	9	7.21e-01	0.068900	0.944000
GO:0007417 central nervous system development	14	6.57e-01	-0.068800	0.926000
GO:0034394 protein localization to cell surface	8	7.39e-01	-0.068200	0.951000
GO:0043209 myelin sheath	6	7.73e-01	0.068200	0.960000
GO:0019901 protein kinase binding	95	2.65e-01	0.067800	0.829000
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding	9	7.26e-01	-0.067600	0.944000
GO:0000781 chromosome, telomeric region	21	5.95e-01	0.067500	0.921000
GO:0071902 positive regulation of protein serine/threonine kinase activity	12	6.87e-01	0.067400	0.938000
GO:0008137 NADH dehydrogenase (ubiquinone) activity	18	6.24e-01	0.067000	0.922000
GO:0043123 positive regulation of canonical NF-kappaB signal transduction	51	4.15e-01	-0.066800	0.888000
GO:0099523 presynaptic cytosol	11	7.03e-01	-0.066700	0.940000
GO:0042470 melanosome	32	5.19e-01	-0.066400	0.894000
GO:0017025 TBP-class protein binding	6	7.79e-01	-0.066200	0.960000
GO:0030324 lung development	5	7.99e-01	-0.066000	0.960000
GO:0035264 multicellular organism growth	17	6.40e-01	-0.065900	0.926000
GO:0010977 negative regulation of neuron projection development	9	7.33e-01	-0.065800	0.950000
GO:0001891 phagocytic cup	10	7.21e-01	0.065500	0.944000
GO:0070212 protein poly-ADP-ribosylation	5	8.00e-01	-0.065400	0.960000
GO:0032691 negative regulation of interleukin-1 beta production	6	7.82e-01	0.065300	0.960000
GO:0030425 dendrite	42	4.70e-01	-0.065200	0.894000
GO:0016604 nuclear body	55	4.13e-01	0.064800	0.886000
GO:0043122 regulation of canonical NF-kappaB signal transduction	8	7.52e-01	0.064600	0.956000
GO:0005635 nuclear envelope	33	5.25e-01	-0.064600	0.894000
GO:0042060 wound healing	10	7.25e-01	0.064400	0.944000
GO:0019899 enzyme binding	80	3.32e-01	0.064000	0.855000
GO:0031334 positive regulation of protein-containing complex assembly	16	6.59e-01	-0.064000	0.926000
GO:0070888 E-box binding	5	8.05e-01	-0.063900	0.960000
GO:0030033 microvillus assembly	7	7.71e-01	-0.063700	0.960000
GO:0030054 cell junction	17	6.51e-01	-0.063600	0.926000
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity	5	8.06e-01	-0.063500	0.960000
GO:0016310 phosphorylation	6	7.89e-01	0.063300	0.960000
GO:0001974 blood vessel remodeling	5	8.07e-01	-0.063200	0.960000
GO:0045429 positive regulation of nitric oxide biosynthetic process	15	6.73e-01	0.063200	0.930000
GO:1990226 histone methyltransferase binding	5	8.08e-01	0.063000	0.960000
GO:0007165 signal transduction	171	1.74e-01	0.063000	0.767000
GO:0001937 negative regulation of endothelial cell proliferation	6	7.90e-01	0.062800	0.960000
GO:0007507 heart development	31	5.50e-01	0.062600	0.897000
GO:0042149 cellular response to glucose starvation	11	7.20e-01	-0.062600	0.944000
GO:0055038 recycling endosome membrane	22	6.15e-01	0.062400	0.922000
GO:0001819 positive regulation of cytokine production	11	7.22e-01	-0.062100	0.944000
GO:0031982 vesicle	42	4.92e-01	0.061900	0.894000
GO:0016281 eukaryotic translation initiation factor 4F complex	5	8.12e-01	0.061500	0.960000
GO:0010467 gene expression	18	6.54e-01	0.061400	0.926000
GO:0050681 nuclear androgen receptor binding	11	7.26e-01	0.061200	0.944000
GO:0032496 response to lipopolysaccharide	22	6.22e-01	-0.061000	0.922000
GO:1990380 K48-linked deubiquitinase activity	5	8.14e-01	-0.060900	0.960000
GO:0030674 protein-macromolecule adaptor activity	29	5.75e-01	0.060700	0.909000
GO:0030669 clathrin-coated endocytic vesicle membrane	15	6.86e-01	-0.060600	0.938000
GO:0005524 ATP binding	194	1.67e-01	0.060500	0.767000
GO:0034774 secretory granule lumen	42	5.02e-01	-0.060500	0.894000
GO:0042645 mitochondrial nucleoid	5	8.15e-01	-0.060500	0.960000
GO:0048143 astrocyte activation	5	8.15e-01	0.060500	0.960000
GO:0032727 positive regulation of interferon-alpha production	7	7.83e-01	-0.060400	0.960000
GO:0071345 cellular response to cytokine stimulus	7	7.83e-01	0.060400	0.960000
GO:0016459 myosin complex	5	8.16e-01	-0.060200	0.960000
GO:0031267 small GTPase binding	56	4.46e-01	0.059700	0.894000
GO:0008284 positive regulation of cell population proliferation	62	4.27e-01	-0.059300	0.891000
GO:0050700 CARD domain binding	6	8.03e-01	-0.059100	0.960000
GO:0008234 cysteine-type peptidase activity	7	7.87e-01	0.059000	0.960000
GO:0006749 glutathione metabolic process	6	8.03e-01	-0.058900	0.960000
GO:0051082 unfolded protein binding	23	6.27e-01	0.058800	0.922000
GO:0006955 immune response	64	4.25e-01	-0.058700	0.891000
GO:1903955 positive regulation of protein targeting to mitochondrion	8	7.76e-01	-0.058300	0.960000
GO:0004386 helicase activity	7	7.90e-01	-0.058200	0.960000
GO:0036464 cytoplasmic ribonucleoprotein granule	28	5.98e-01	0.058000	0.921000
GO:0001533 cornified envelope	5	8.23e-01	-0.057900	0.960000
GO:0005096 GTPase activator activity	50	4.85e-01	-0.057800	0.894000
GO:0007162 negative regulation of cell adhesion	7	7.92e-01	0.057600	0.960000
GO:0033209 tumor necrosis factor-mediated signaling pathway	15	7.01e-01	-0.057500	0.940000
GO:1903078 positive regulation of protein localization to plasma membrane	11	7.42e-01	-0.057400	0.953000
GO:0051881 regulation of mitochondrial membrane potential	8	7.79e-01	-0.057300	0.960000
GO:0007266 Rho protein signal transduction	13	7.22e-01	0.057200	0.944000
GO:0008135 translation factor activity, RNA binding	8	7.80e-01	-0.057100	0.960000
GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	8	7.80e-01	-0.057100	0.960000
GO:0007041 lysosomal transport	5	8.26e-01	0.056800	0.960000
GO:0036002 pre-mRNA binding	10	7.57e-01	0.056700	0.956000
GO:0000775 chromosome, centromeric region	11	7.47e-01	-0.056400	0.953000
GO:0035091 phosphatidylinositol binding	13	7.26e-01	0.056300	0.944000
GO:0030426 growth cone	19	6.73e-01	0.056100	0.930000
GO:0030833 regulation of actin filament polymerization	8	7.84e-01	0.056100	0.960000
GO:0061133 endopeptidase activator activity	5	8.29e-01	0.056000	0.960000
GO:0000139 Golgi membrane	96	3.56e-01	-0.055900	0.863000
GO:0035176 social behavior	6	8.13e-01	0.055900	0.960000
GO:1900745 positive regulation of p38MAPK cascade	5	8.29e-01	0.055800	0.960000
GO:0006368 transcription elongation by RNA polymerase II	7	7.99e-01	0.055600	0.960000
GO:0030424 axon	38	5.57e-01	0.055600	0.903000
GO:0030658 transport vesicle membrane	11	7.50e-01	-0.055600	0.954000
GO:0031625 ubiquitin protein ligase binding	85	3.89e-01	0.055300	0.883000
GO:0044194 cytolytic granule	9	7.75e-01	0.055100	0.960000
GO:0005791 rough endoplasmic reticulum	11	7.53e-01	-0.054900	0.956000
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway	5	8.32e-01	-0.054900	0.960000
GO:0005178 integrin binding	29	6.13e-01	-0.054700	0.922000
GO:0005886 plasma membrane	545	6.29e-02	0.054600	0.706000
GO:0007268 chemical synaptic transmission	12	7.45e-01	-0.054500	0.953000
GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m	5	8.33e-01	0.054500	0.960000
GO:0060337 type I interferon-mediated signaling pathway	10	7.69e-01	-0.053800	0.960000
GO:0042127 regulation of cell population proliferation	30	6.15e-01	0.053400	0.922000
GO:0030134 COPII-coated ER to Golgi transport vesicle	5	8.36e-01	0.053400	0.960000
GO:0030544 Hsp70 protein binding	8	7.94e-01	-0.053300	0.960000
GO:0060090 molecular adaptor activity	41	5.60e-01	-0.053200	0.903000
GO:0050796 regulation of insulin secretion	7	8.10e-01	0.052700	0.960000
GO:0018108 peptidyl-tyrosine phosphorylation	9	7.85e-01	0.052600	0.960000
GO:0000381 regulation of alternative mRNA splicing, via spliceosome	20	6.86e-01	0.052500	0.938000
GO:0007005 mitochondrion organization	16	7.19e-01	-0.052200	0.944000
GO:0070254 mucus secretion	5	8.40e-01	-0.052100	0.960000
GO:0004896 cytokine receptor activity	6	8.25e-01	0.052100	0.960000
GO:0090398 cellular senescence	13	7.47e-01	-0.052000	0.953000
GO:0050830 defense response to Gram-positive bacterium	19	6.97e-01	-0.051800	0.940000
GO:0007026 negative regulation of microtubule depolymerization	5	8.42e-01	0.051500	0.960000
GO:0003700 DNA-binding transcription factor activity	51	5.31e-01	-0.051400	0.894000
GO:0045177 apical part of cell	10	7.80e-01	-0.051200	0.960000
GO:0032675 regulation of interleukin-6 production	5	8.44e-01	-0.050800	0.960000
GO:1990841 promoter-specific chromatin binding	18	7.10e-01	0.050800	0.944000
GO:0030968 endoplasmic reticulum unfolded protein response	9	7.93e-01	0.050600	0.960000
GO:0140311 protein sequestering activity	12	7.62e-01	0.050600	0.959000
GO:0005654 nucleoplasm	630	7.40e-02	0.050500	0.743000
GO:0031072 heat shock protein binding	12	7.64e-01	0.050200	0.960000
GO:0007409 axonogenesis	10	7.85e-01	-0.050000	0.960000
GO:1990606 membrane scission GTPase motor activity	10	7.87e-01	-0.049500	0.960000
GO:0071944 cell periphery	14	7.50e-01	0.049500	0.954000
GO:0006979 response to oxidative stress	13	7.59e-01	0.049400	0.956000
GO:0030667 secretory granule membrane	32	6.32e-01	-0.049300	0.923000
GO:0005911 cell-cell junction	34	6.23e-01	0.049200	0.922000
GO:0032728 positive regulation of interferon-beta production	11	7.79e-01	0.049000	0.960000
GO:0001558 regulation of cell growth	6	8.36e-01	0.048900	0.960000
GO:0010508 positive regulation of autophagy	19	7.14e-01	0.048800	0.944000
GO:0030217 T cell differentiation	8	8.13e-01	-0.048500	0.960000
GO:0048813 dendrite morphogenesis	7	8.25e-01	0.048400	0.960000
GO:2000736 regulation of stem cell differentiation	6	8.38e-01	-0.048400	0.960000
GO:0071277 cellular response to calcium ion	14	7.55e-01	-0.048300	0.956000
GO:0005930 axoneme	10	7.92e-01	-0.048300	0.960000
GO:0030163 protein catabolic process	8	8.14e-01	-0.048200	0.960000
GO:0042734 presynaptic membrane	8	8.14e-01	-0.048100	0.960000
GO:0005923 bicellular tight junction	11	7.83e-01	0.048100	0.960000
GO:0001503 ossification	7	8.26e-01	0.048000	0.960000
GO:0031386 protein tag activity	9	8.04e-01	-0.048000	0.960000
GO:0007155 cell adhesion	41	6.00e-01	-0.047900	0.921000
GO:0035556 intracellular signal transduction	72	4.91e-01	0.047800	0.894000
GO:0045668 negative regulation of osteoblast differentiation	5	8.55e-01	-0.047400	0.962000
GO:0045921 positive regulation of exocytosis	6	8.42e-01	-0.047100	0.960000
GO:0035267 NuA4 histone acetyltransferase complex	5	8.56e-01	0.047000	0.962000
GO:0000149 SNARE binding	10	7.98e-01	0.046900	0.960000
GO:0072659 protein localization to plasma membrane	23	6.99e-01	0.046800	0.940000
GO:0030246 carbohydrate binding	13	7.72e-01	-0.046600	0.960000
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	6	8.44e-01	-0.046600	0.960000
GO:0032154 cleavage furrow	10	8.00e-01	0.046500	0.960000
GO:0042254 ribosome biogenesis	6	8.44e-01	-0.046400	0.960000
GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)	5	8.58e-01	-0.046300	0.963000
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	7	8.32e-01	0.046300	0.960000
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process	17	7.43e-01	-0.046200	0.953000
GO:0045121 membrane raft	40	6.17e-01	0.046200	0.922000
GO:0032588 trans-Golgi network membrane	21	7.16e-01	-0.046100	0.944000
GO:0015914 phospholipid transport	6	8.47e-01	0.045700	0.961000
GO:0035025 positive regulation of Rho protein signal transduction	5	8.60e-01	-0.045500	0.965000
GO:0005521 lamin binding	5	8.61e-01	0.045300	0.965000
GO:0045577 regulation of B cell differentiation	5	8.61e-01	-0.045300	0.965000
GO:0003925 G protein activity	17	7.48e-01	-0.045200	0.954000
GO:0035925 mRNA 3’-UTR AU-rich region binding	6	8.48e-01	0.045100	0.961000
GO:0050680 negative regulation of epithelial cell proliferation	8	8.26e-01	0.045000	0.960000
GO:0008013 beta-catenin binding	17	7.50e-01	0.044800	0.954000
GO:0001916 positive regulation of T cell mediated cytotoxicity	9	8.17e-01	0.044600	0.960000
GO:0097431 mitotic spindle pole	5	8.63e-01	0.044600	0.966000
GO:0043547 positive regulation of GTPase activity	19	7.38e-01	-0.044500	0.951000
GO:0038066 p38MAPK cascade	6	8.51e-01	0.044300	0.962000
GO:0050808 synapse organization	5	8.64e-01	0.044200	0.967000
GO:0006629 lipid metabolic process	10	8.10e-01	0.044000	0.960000
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway	10	8.10e-01	-0.044000	0.960000
GO:0045296 cadherin binding	94	4.72e-01	-0.044000	0.894000
GO:0019902 phosphatase binding	8	8.30e-01	-0.043900	0.960000
GO:0097242 amyloid-beta clearance	7	8.42e-01	-0.043700	0.960000
GO:0007520 myoblast fusion	6	8.54e-01	0.043500	0.962000
GO:0005685 U1 snRNP	7	8.42e-01	-0.043500	0.960000
GO:0000902 cell morphogenesis	20	7.38e-01	-0.043500	0.951000
GO:0050807 regulation of synapse organization	5	8.67e-01	-0.043300	0.968000
GO:0003823 antigen binding	9	8.22e-01	-0.043300	0.960000
GO:0031966 mitochondrial membrane	32	6.75e-01	0.043200	0.930000
GO:0045746 negative regulation of Notch signaling pathway	6	8.55e-01	0.043200	0.962000
GO:0042802 identical protein binding	241	2.80e-01	-0.043100	0.829000
GO:0090148 membrane fission	5	8.68e-01	0.042900	0.968000
GO:0031490 chromatin DNA binding	21	7.36e-01	0.042700	0.951000
GO:0005759 mitochondrial matrix	25	7.15e-01	0.042500	0.944000
GO:1990904 ribonucleoprotein complex	59	5.78e-01	0.042500	0.911000
GO:0001666 response to hypoxia	29	6.96e-01	0.042300	0.940000
GO:0048026 positive regulation of mRNA splicing, via spliceosome	9	8.28e-01	-0.042000	0.960000
GO:0002224 toll-like receptor signaling pathway	8	8.40e-01	0.041400	0.960000
GO:0050679 positive regulation of epithelial cell proliferation	7	8.50e-01	0.041400	0.961000
GO:0045944 positive regulation of transcription by RNA polymerase II	197	3.42e-01	0.041300	0.856000
GO:0008143 poly(A) binding	8	8.40e-01	0.041300	0.960000
GO:0007040 lysosome organization	7	8.50e-01	-0.041200	0.961000
GO:0007399 nervous system development	32	6.89e-01	0.041200	0.938000
GO:0140588 chromatin looping	23	7.34e-01	-0.041100	0.950000
GO:0060397 growth hormone receptor signaling pathway via JAK-STAT	5	8.74e-01	0.041000	0.970000
GO:0036258 multivesicular body assembly	7	8.53e-01	-0.040500	0.962000
GO:0016887 ATP hydrolysis activity	52	6.18e-01	0.040500	0.922000
GO:0042552 myelination	10	8.25e-01	0.040500	0.960000
GO:0005743 mitochondrial inner membrane	80	5.42e-01	-0.040300	0.894000
GO:0031398 positive regulation of protein ubiquitination	20	7.57e-01	0.040100	0.956000
GO:0042119 neutrophil activation	5	8.77e-01	0.040100	0.972000
GO:0042803 protein homodimerization activity	94	5.12e-01	0.040100	0.894000
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific	80	5.44e-01	0.040100	0.894000
GO:1990000 amyloid fibril formation	7	8.55e-01	0.040000	0.962000
GO:0034644 cellular response to UV	13	8.05e-01	0.039700	0.960000
GO:0005770 late endosome	35	6.88e-01	0.039600	0.938000
GO:0001222 transcription corepressor binding	18	7.73e-01	0.039500	0.960000
GO:0016607 nuclear speck	100	5.07e-01	0.039400	0.894000
GO:0043024 ribosomal small subunit binding	5	8.79e-01	0.039300	0.973000
GO:0004175 endopeptidase activity	12	8.16e-01	-0.039000	0.960000
GO:0003682 chromatin binding	73	5.72e-01	0.039000	0.909000
GO:0007163 establishment or maintenance of cell polarity	11	8.24e-01	-0.038900	0.960000
GO:0005758 mitochondrial intermembrane space	14	8.03e-01	-0.038700	0.960000
GO:0006895 Golgi to endosome transport	5	8.81e-01	0.038600	0.973000
GO:0060586 multicellular organismal-level iron ion homeostasis	6	8.71e-01	-0.038400	0.970000
GO:0035234 ectopic germ cell programmed cell death	6	8.72e-01	-0.038200	0.970000
GO:0030672 synaptic vesicle membrane	18	7.80e-01	0.038100	0.960000
GO:0098586 cellular response to virus	23	7.55e-01	0.037800	0.956000
GO:0098793 presynapse	32	7.14e-01	0.037800	0.944000
GO:0048660 regulation of smooth muscle cell proliferation	5	8.84e-01	0.037800	0.973000
GO:0098978 glutamatergic synapse	83	5.61e-01	0.037700	0.903000
GO:0005102 signaling receptor binding	47	6.59e-01	0.037700	0.926000
GO:0043130 ubiquitin binding	17	7.89e-01	0.037600	0.960000
GO:0016323 basolateral plasma membrane	26	7.42e-01	0.037500	0.953000
GO:0005515 protein binding	1599	3.20e-01	0.037500	0.851000
GO:0010667 negative regulation of cardiac muscle cell apoptotic process	5	8.85e-01	-0.037300	0.973000
GO:0050850 positive regulation of calcium-mediated signaling	9	8.48e-01	0.037100	0.961000
GO:0000932 P-body	26	7.46e-01	-0.037000	0.953000
GO:0043025 neuronal cell body	41	6.85e-01	0.037000	0.938000
GO:0001650 fibrillar center	18	7.87e-01	-0.037000	0.960000
GO:0050839 cell adhesion molecule binding	10	8.40e-01	-0.036900	0.960000
GO:0002102 podosome	14	8.12e-01	0.036900	0.960000
GO:0035591 signaling adaptor activity	17	7.94e-01	-0.036800	0.960000
GO:0034451 centriolar satellite	10	8.42e-01	-0.036600	0.960000
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway	7	8.68e-01	0.036500	0.968000
GO:0012507 ER to Golgi transport vesicle membrane	16	8.02e-01	-0.036500	0.960000
GO:0030010 establishment of cell polarity	6	8.78e-01	0.036400	0.972000
GO:0030660 Golgi-associated vesicle membrane	5	8.88e-01	-0.036300	0.974000
GO:0070935 3’-UTR-mediated mRNA stabilization	7	8.69e-01	-0.036200	0.968000
GO:0010613 positive regulation of cardiac muscle hypertrophy	5	8.89e-01	0.036100	0.974000
GO:0030139 endocytic vesicle	11	8.36e-01	0.036100	0.960000
GO:0070062 extracellular exosome	450	2.49e-01	-0.036000	0.829000
GO:0036211 protein modification process	17	7.99e-01	-0.035800	0.960000
GO:0031965 nuclear membrane	46	6.79e-01	0.035700	0.934000
GO:0005925 focal adhesion	159	4.55e-01	-0.035700	0.894000
GO:0000245 spliceosomal complex assembly	7	8.70e-01	-0.035700	0.969000
GO:0070269 pyroptotic inflammatory response	10	8.45e-01	-0.035700	0.960000
GO:0006935 chemotaxis	15	8.14e-01	-0.035200	0.960000
GO:0030136 clathrin-coated vesicle	16	8.09e-01	0.035100	0.960000
GO:0015630 microtubule cytoskeleton	28	7.50e-01	0.035000	0.954000
GO:0150104 transport across blood-brain barrier	7	8.74e-01	0.034700	0.970000
GO:0030552 cAMP binding	5	8.94e-01	-0.034600	0.978000
GO:0043410 positive regulation of MAPK cascade	23	7.76e-01	0.034500	0.960000
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation	6	8.84e-01	0.034400	0.973000
GO:0005814 centriole	13	8.31e-01	-0.034300	0.960000
GO:0010976 positive regulation of neuron projection development	17	8.08e-01	0.034200	0.960000
GO:0001843 neural tube closure	8	8.67e-01	0.034200	0.968000
GO:0006968 cellular defense response	12	8.41e-01	-0.033600	0.960000
GO:0032743 positive regulation of interleukin-2 production	14	8.29e-01	-0.033400	0.960000
GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	6	8.88e-01	-0.033200	0.974000
GO:0008544 epidermis development	5	8.99e-01	0.032900	0.980000
GO:0044853 plasma membrane raft	7	8.81e-01	-0.032800	0.973000
GO:0043029 T cell homeostasis	8	8.75e-01	-0.032300	0.970000
GO:0019082 viral protein processing	7	8.84e-01	0.031900	0.973000
GO:0003730 mRNA 3’-UTR binding	26	7.80e-01	-0.031900	0.960000
GO:0006897 endocytosis	33	7.54e-01	0.031900	0.956000
GO:0048144 fibroblast proliferation	5	9.02e-01	-0.031800	0.982000
GO:0003690 double-stranded DNA binding	20	8.07e-01	0.031700	0.960000
GO:0042742 defense response to bacterium	26	7.82e-01	0.031600	0.960000
GO:0060070 canonical Wnt signaling pathway	13	8.45e-01	0.031500	0.960000
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity	14	8.44e-01	-0.030500	0.960000
GO:0030946 protein tyrosine phosphatase activity, metal-dependent	14	8.44e-01	-0.030500	0.960000
GO:0140793 histone H2AXY142 phosphatase activity	14	8.44e-01	-0.030500	0.960000
GO:0008289 lipid binding	22	8.07e-01	0.030300	0.960000
GO:0051260 protein homooligomerization	11	8.64e-01	-0.029900	0.967000
GO:0043005 neuron projection	28	7.86e-01	0.029800	0.960000
GO:0090023 positive regulation of neutrophil chemotaxis	8	8.84e-01	0.029700	0.973000
GO:0033017 sarcoplasmic reticulum membrane	5	9.11e-01	0.029000	0.986000
GO:0006401 RNA catabolic process	5	9.11e-01	0.028800	0.986000
GO:0031647 regulation of protein stability	23	8.12e-01	-0.028800	0.960000
GO:0009986 cell surface	80	6.64e-01	-0.028600	0.928000
GO:0006446 regulation of translational initiation	14	8.55e-01	-0.028300	0.962000
GO:0003689 DNA clamp loader activity	20	8.27e-01	-0.028300	0.960000
GO:0140584 chromatin extrusion motor activity	20	8.27e-01	-0.028300	0.960000
GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity	20	8.27e-01	-0.028300	0.960000
GO:0140849 ATP-dependent H2AZ histone chaperone activity	20	8.27e-01	-0.028300	0.960000
GO:0043539 protein serine/threonine kinase activator activity	17	8.41e-01	-0.028300	0.960000
GO:0042383 sarcolemma	17	8.42e-01	-0.028000	0.960000
GO:0030666 endocytic vesicle membrane	23	8.18e-01	0.027900	0.960000
GO:0032869 cellular response to insulin stimulus	16	8.49e-01	0.027700	0.961000
GO:0005819 spindle	21	8.28e-01	0.027500	0.960000
GO:0006511 ubiquitin-dependent protein catabolic process	44	7.55e-01	0.027500	0.956000
GO:1904044 response to aldosterone	5	9.15e-01	-0.027500	0.986000
GO:0006351 DNA-templated transcription	8	8.93e-01	-0.027500	0.978000
GO:0033077 T cell differentiation in thymus	8	8.95e-01	-0.026900	0.979000
GO:0043065 positive regulation of apoptotic process	66	7.13e-01	0.026600	0.944000
GO:0007565 female pregnancy	8	8.97e-01	0.026500	0.979000
GO:0051726 regulation of cell cycle	42	7.71e-01	-0.026300	0.960000
GO:0003677 DNA binding	150	5.95e-01	0.026100	0.921000
GO:0007204 positive regulation of cytosolic calcium ion concentration	11	8.82e-01	-0.026000	0.973000
GO:0014850 response to muscle activity	6	9.13e-01	0.025700	0.986000
GO:0000159 protein phosphatase type 2A complex	6	9.15e-01	0.025300	0.986000
GO:0030514 negative regulation of BMP signaling pathway	7	9.08e-01	-0.025200	0.986000
GO:0001541 ovarian follicle development	6	9.15e-01	-0.025200	0.986000
GO:0003729 mRNA binding	72	7.20e-01	-0.024900	0.944000
GO:0008360 regulation of cell shape	35	8.04e-01	0.024500	0.960000
GO:0005667 transcription regulator complex	31	8.18e-01	0.024100	0.960000
GO:0097193 intrinsic apoptotic signaling pathway	12	8.86e-01	-0.024000	0.973000
GO:0003678 DNA helicase activity	5	9.27e-01	-0.023900	0.987000
GO:0007229 integrin-mediated signaling pathway	28	8.31e-01	0.023500	0.960000
GO:0008092 cytoskeletal protein binding	8	9.09e-01	0.023400	0.986000
GO:0031116 positive regulation of microtubule polymerization	5	9.28e-01	0.023400	0.987000
GO:0071480 cellular response to gamma radiation	5	9.28e-01	0.023400	0.987000
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific	52	7.73e-01	-0.023400	0.960000
GO:0045727 positive regulation of translation	23	8.49e-01	-0.023000	0.961000
GO:0003151 outflow tract morphogenesis	8	9.12e-01	0.022600	0.986000
GO:0004843 cysteine-type deubiquitinase activity	17	8.74e-01	0.022300	0.970000
GO:0005768 endosome	47	7.97e-01	0.022000	0.960000
GO:0071230 cellular response to amino acid stimulus	9	9.10e-01	0.021900	0.986000
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding	41	8.11e-01	-0.021900	0.960000
GO:0007369 gastrulation	6	9.27e-01	0.021800	0.987000
GO:0044877 protein-containing complex binding	54	7.86e-01	0.021700	0.960000
GO:0034446 substrate adhesion-dependent cell spreading	10	9.06e-01	0.021700	0.984000
GO:0030099 myeloid cell differentiation	8	9.16e-01	0.021600	0.986000
GO:0032526 response to retinoic acid	5	9.34e-01	-0.021500	0.987000
GO:0120183 positive regulation of focal adhesion disassembly	5	9.34e-01	-0.021500	0.987000
GO:0051649 establishment of localization in cell	7	9.22e-01	0.021300	0.987000
GO:0021756 striatum development	5	9.34e-01	-0.021300	0.987000
GO:0002062 chondrocyte differentiation	9	9.14e-01	-0.020900	0.986000
GO:0038202 TORC1 signaling	5	9.36e-01	-0.020700	0.987000
GO:0002250 adaptive immune response	40	8.24e-01	0.020600	0.960000
GO:0021549 cerebellum development	8	9.21e-01	0.020400	0.987000
GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	5	9.38e-01	0.020200	0.987000
GO:0006457 protein folding	27	8.57e-01	-0.020100	0.963000
GO:0004842 ubiquitin-protein transferase activity	40	8.31e-01	-0.019700	0.960000
GO:0071333 cellular response to glucose stimulus	13	9.03e-01	-0.019600	0.982000
GO:0043236 laminin binding	7	9.29e-01	-0.019500	0.987000
GO:0071479 cellular response to ionizing radiation	9	9.20e-01	0.019500	0.987000
GO:0101031 protein folding chaperone complex	6	9.34e-01	-0.019500	0.987000
GO:0051928 positive regulation of calcium ion transport	5	9.40e-01	0.019400	0.987000
GO:0016491 oxidoreductase activity	8	9.25e-01	-0.019300	0.987000
GO:0004708 MAP kinase kinase activity	5	9.41e-01	0.019200	0.987000
GO:0046961 proton-transporting ATPase activity, rotational mechanism	8	9.26e-01	0.019000	0.987000
GO:0006974 DNA damage response	58	8.06e-01	0.018900	0.960000
GO:0032008 positive regulation of TOR signaling	6	9.37e-01	-0.018700	0.987000
GO:0051289 protein homotetramerization	8	9.29e-01	0.018400	0.987000
GO:0090307 mitotic spindle assembly	10	9.23e-01	0.017800	0.987000
GO:0043001 Golgi to plasma membrane protein transport	7	9.36e-01	0.017500	0.987000
GO:0031669 cellular response to nutrient levels	7	9.37e-01	-0.017400	0.987000
GO:0016192 vesicle-mediated transport	23	8.86e-01	0.017400	0.973000
GO:0006513 protein monoubiquitination	9	9.28e-01	-0.017300	0.987000
GO:0043197 dendritic spine	19	8.96e-01	0.017300	0.979000
GO:0005634 nucleus	806	5.22e-01	0.017300	0.894000
GO:0008270 zinc ion binding	106	7.67e-01	0.017100	0.960000
GO:0007052 mitotic spindle organization	9	9.31e-01	-0.016700	0.987000
GO:0060907 positive regulation of macrophage cytokine production	9	9.31e-01	0.016600	0.987000
GO:0007611 learning or memory	11	9.25e-01	-0.016500	0.987000
GO:0045171 intercellular bridge	9	9.32e-01	0.016500	0.987000
GO:0031175 neuron projection development	20	9.00e-01	0.016300	0.980000
GO:0045892 negative regulation of DNA-templated transcription	99	7.86e-01	-0.016200	0.960000
GO:0016064 immunoglobulin mediated immune response	8	9.37e-01	0.016100	0.987000
GO:0038180 nerve growth factor signaling pathway	5	9.52e-01	-0.015700	0.989000
GO:0030016 myofibril	6	9.47e-01	0.015700	0.989000
GO:0001817 regulation of cytokine production	10	9.32e-01	0.015700	0.987000
GO:0014070 response to organic cyclic compound	7	9.43e-01	-0.015500	0.987000
GO:0005506 iron ion binding	9	9.36e-01	-0.015400	0.987000
GO:0008320 protein transmembrane transporter activity	5	9.53e-01	-0.015300	0.989000
GO:0097038 perinuclear endoplasmic reticulum	5	9.53e-01	0.015300	0.989000
GO:0001782 B cell homeostasis	11	9.31e-01	-0.015100	0.987000
GO:0035924 cellular response to vascular endothelial growth factor stimulus	7	9.45e-01	0.015100	0.988000
GO:0007283 spermatogenesis	37	8.77e-01	0.014800	0.972000
GO:0032753 positive regulation of interleukin-4 production	6	9.50e-01	0.014800	0.989000
GO:0005509 calcium ion binding	73	8.32e-01	-0.014600	0.960000
GO:0016581 NuRD complex	5	9.55e-01	-0.014400	0.989000
GO:0042277 peptide binding	5	9.55e-01	0.014400	0.989000
GO:0032720 negative regulation of tumor necrosis factor production	10	9.39e-01	-0.014100	0.987000
GO:0045111 intermediate filament cytoskeleton	9	9.42e-01	0.014000	0.987000
GO:0004706 JUN kinase kinase kinase activity	6	9.53e-01	-0.013900	0.989000
GO:0043565 sequence-specific DNA binding	31	8.95e-01	0.013800	0.979000
GO:0010595 positive regulation of endothelial cell migration	10	9.40e-01	0.013800	0.987000
GO:0071498 cellular response to fluid shear stress	7	9.50e-01	-0.013700	0.989000
GO:0045453 bone resorption	6	9.56e-01	0.013000	0.989000
GO:0060252 positive regulation of glial cell proliferation	6	9.56e-01	0.013000	0.989000
GO:0034063 stress granule assembly	12	9.39e-01	-0.012900	0.987000
GO:0005829 cytosol	955	6.32e-01	0.012800	0.923000
GO:0071260 cellular response to mechanical stimulus	11	9.42e-01	0.012700	0.987000
GO:0016020 membrane	494	6.81e-01	-0.012400	0.936000
GO:2001234 negative regulation of apoptotic signaling pathway	6	9.59e-01	-0.012100	0.989000
GO:0007517 muscle organ development	12	9.43e-01	-0.012000	0.987000
GO:0070936 protein K48-linked ubiquitination	29	9.13e-01	-0.011800	0.986000
GO:0075522 IRES-dependent viral translational initiation	5	9.64e-01	0.011700	0.990000
GO:0007519 skeletal muscle tissue development	7	9.58e-01	0.011400	0.989000
GO:0045211 postsynaptic membrane	8	9.57e-01	0.011000	0.989000
GO:0004860 protein kinase inhibitor activity	7	9.60e-01	-0.010900	0.989000
GO:0050821 protein stabilization	48	9.00e-01	0.010700	0.980000
GO:0051010 microtubule plus-end binding	6	9.65e-01	-0.010300	0.990000
GO:0015629 actin cytoskeleton	55	8.98e-01	0.010200	0.979000
GO:0010572 positive regulation of platelet activation	6	9.66e-01	0.009990	0.990000
GO:0009897 external side of plasma membrane	47	9.07e-01	0.009930	0.986000
GO:0006096 glycolytic process	9	9.60e-01	-0.009710	0.989000
GO:0006605 protein targeting	11	9.56e-01	0.009710	0.989000
GO:0031252 cell leading edge	12	9.54e-01	0.009670	0.989000
GO:0030182 neuron differentiation	20	9.42e-01	-0.009490	0.987000
GO:0004888 transmembrane signaling receptor activity	16	9.49e-01	0.009280	0.989000
GO:0005200 structural constituent of cytoskeleton	25	9.37e-01	-0.009240	0.987000
GO:0060291 long-term synaptic potentiation	6	9.70e-01	0.008920	0.991000
GO:0042776 proton motive force-driven mitochondrial ATP synthesis	32	9.33e-01	0.008720	0.987000
GO:0001822 kidney development	5	9.73e-01	0.008670	0.991000
GO:0006879 intracellular iron ion homeostasis	13	9.57e-01	0.008640	0.989000
GO:0070577 lysine-acetylated histone binding	9	9.64e-01	-0.008640	0.990000
GO:0120162 positive regulation of cold-induced thermogenesis	12	9.59e-01	-0.008500	0.989000
GO:0021542 dentate gyrus development	5	9.74e-01	0.008450	0.991000
GO:0030048 actin filament-based movement	7	9.70e-01	-0.008340	0.991000
GO:0045471 response to ethanol	19	9.51e-01	0.008260	0.989000
GO:0006915 apoptotic process	117	8.82e-01	-0.008200	0.973000
GO:0042995 cell projection	28	9.43e-01	-0.007930	0.987000
GO:0006816 calcium ion transport	10	9.66e-01	0.007830	0.990000
GO:0030148 sphingolipid biosynthetic process	6	9.74e-01	0.007670	0.991000
GO:0019722 calcium-mediated signaling	13	9.63e-01	-0.007480	0.990000
GO:0030335 positive regulation of cell migration	48	9.30e-01	0.007420	0.987000
GO:0051056 regulation of small GTPase mediated signal transduction	19	9.60e-01	0.006670	0.989000
GO:0044295 axonal growth cone	7	9.76e-01	-0.006660	0.991000
GO:0030331 nuclear estrogen receptor binding	10	9.71e-01	0.006550	0.991000
GO:0035722 interleukin-12-mediated signaling pathway	5	9.80e-01	0.006530	0.993000
GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process	5	9.80e-01	0.006530	0.993000
GO:0003712 transcription coregulator activity	29	9.54e-01	-0.006220	0.989000
GO:0034614 cellular response to reactive oxygen species	8	9.76e-01	-0.006160	0.991000
GO:0000028 ribosomal small subunit assembly	9	9.75e-01	-0.006140	0.991000
GO:0051301 cell division	49	9.44e-01	-0.005850	0.988000
GO:0043231 intracellular membrane-bounded organelle	112	9.18e-01	-0.005820	0.987000
GO:0032587 ruffle membrane	25	9.60e-01	0.005780	0.989000
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway	11	9.76e-01	0.005320	0.991000
GO:1901888 regulation of cell junction assembly	5	9.84e-01	-0.005240	0.993000
GO:0001649 osteoblast differentiation	17	9.71e-01	-0.005160	0.991000
GO:0009725 response to hormone	7	9.81e-01	-0.005130	0.993000
GO:0060326 cell chemotaxis	9	9.80e-01	0.004940	0.993000
GO:0000082 G1/S transition of mitotic cell cycle	13	9.76e-01	-0.004840	0.991000
GO:0005739 mitochondrion	200	9.11e-01	-0.004830	0.986000
GO:0031901 early endosome membrane	31	9.64e-01	-0.004670	0.990000
GO:0009611 response to wounding	7	9.84e-01	0.004510	0.993000
GO:0016779 nucleotidyltransferase activity	5	9.86e-01	0.004390	0.994000
GO:0060271 cilium assembly	14	9.78e-01	-0.004300	0.992000
GO:0042267 natural killer cell mediated cytotoxicity	10	9.81e-01	0.004290	0.993000
GO:0048675 axon extension	7	9.85e-01	0.004210	0.993000
GO:0005737 cytoplasm	801	8.81e-01	-0.004040	0.973000
GO:0005085 guanyl-nucleotide exchange factor activity	47	9.64e-01	-0.003830	0.990000
GO:0034612 response to tumor necrosis factor	7	9.87e-01	0.003600	0.994000
GO:0005802 trans-Golgi network	29	9.74e-01	0.003460	0.991000
GO:0050852 T cell receptor signaling pathway	35	9.73e-01	0.003340	0.991000
GO:0046598 positive regulation of viral entry into host cell	6	9.89e-01	-0.003210	0.994000
GO:0010575 positive regulation of vascular endothelial growth factor production	8	9.88e-01	0.003080	0.994000
GO:0016579 protein deubiquitination	15	9.84e-01	-0.002980	0.993000
GO:0007249 canonical NF-kappaB signal transduction	11	9.87e-01	0.002780	0.994000
GO:0010628 positive regulation of gene expression	70	9.72e-01	0.002490	0.991000
GO:0032465 regulation of cytokinesis	9	9.90e-01	-0.002440	0.995000
GO:0050727 regulation of inflammatory response	21	9.86e-01	0.002240	0.994000
GO:1900242 regulation of synaptic vesicle endocytosis	8	9.92e-01	0.002010	0.996000
GO:1904813 ficolin-1-rich granule lumen	47	9.82e-01	-0.001870	0.993000
GO:0051604 protein maturation	9	9.93e-01	0.001730	0.996000
GO:0008286 insulin receptor signaling pathway	15	9.93e-01	-0.001400	0.996000
GO:0002376 immune system process	7	9.95e-01	0.001300	0.997000
GO:0048024 regulation of mRNA splicing, via spliceosome	10	9.97e-01	-0.000751	0.998000
GO:0061775 cohesin loader activity	21	9.96e-01	-0.000694	0.997000
GO:0018149 peptide cross-linking	5	9.98e-01	-0.000535	0.999000
GO:0051491 positive regulation of filopodium assembly	6	9.99e-01	0.000357	0.999000

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Detailed Gene set reports

GO:0007492 endoderm development

set	GO:0007492 endoderm development
setSize	5
pANOVA	0.00277
s.dist	0.773
p.adjustANOVA	0.295

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TNRC6A	871
BPTF	795
EXT1	739
SMAD3	703
TGFB1	252

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TNRC6A	871
BPTF	795
EXT1	739
SMAD3	703
TGFB1	252

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GO:0031624 ubiquitin conjugating enzyme binding

set	GO:0031624 ubiquitin conjugating enzyme binding
setSize	6
pANOVA	0.00431
s.dist	0.674
p.adjustANOVA	0.367

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ARIH1	799
RNF19A	744
RNF125	648
ZMYM2	647
ARIH2	326
RNF144B	308

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ARIH1	799
RNF19A	744
RNF125	648
ZMYM2	647
ARIH2	326
RNF144B	308

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GO:1901526 positive regulation of mitophagy

set	GO:1901526 positive regulation of mitophagy
setSize	5
pANOVA	0.0112
s.dist	0.655
p.adjustANOVA	0.491

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HIF1A	802
HTT	798
VPS13D	606
SLC25A5	364
AMBRA1	240

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HIF1A	802
HTT	798
VPS13D	606
SLC25A5	364
AMBRA1	240

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GO:0042162 telomeric DNA binding

set	GO:0042162 telomeric DNA binding
setSize	7
pANOVA	0.00278
s.dist	0.654
p.adjustANOVA	0.295

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NCL	823
UPF2	723
HNRNPD	613
SMG1	573
XRCC6	510
SMG6	499
XRCC5	177

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NCL	823
UPF2	723
HNRNPD	613
SMG1	573
XRCC6	510
SMG6	499
XRCC5	177

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GO:0015026 coreceptor activity

set	GO:0015026 coreceptor activity
setSize	5
pANOVA	0.0148
s.dist	0.63
p.adjustANOVA	0.554

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TGFBR3	693
ITGB1	651
CXCR4	536
ITGA4	406
CD86	405

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TGFBR3	693
ITGB1	651
CXCR4	536
ITGA4	406
CD86	405

---

GO:0000123 histone acetyltransferase complex

set	GO:0000123 histone acetyltransferase complex
setSize	5
pANOVA	0.0163
s.dist	0.621
p.adjustANOVA	0.554

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KANSL1	866
OGT	789
CREBBP	595
PHF20	559
EP300	-161

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KANSL1	866
OGT	789
CREBBP	595
PHF20	559
EP300	-161

---

GO:0033962 P-body assembly

set	GO:0033962 P-body assembly
setSize	5
pANOVA	0.0173
s.dist	0.615
p.adjustANOVA	0.554

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TNRC6A	871
LSM14A	681
RC3H1	680
DYNC1H1	572
DDX6	-182

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TNRC6A	871
LSM14A	681
RC3H1	680
DYNC1H1	572
DDX6	-182

---

GO:0009966 regulation of signal transduction

set	GO:0009966 regulation of signal transduction
setSize	10
pANOVA	0.000816
s.dist	0.612
p.adjustANOVA	0.174

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PPP6R3	860
PPP6R1	858
PPP6R2	824
GRK5	819
GNAS	710
CDK13	670
MTCH1	341
CDC42SE2	317
NCALD	281
HPCAL1	-479

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PPP6R3	860
PPP6R1	858
PPP6R2	824
GRK5	819
GNAS	710
CDK13	670
MTCH1	341
CDC42SE2	317
NCALD	281
HPCAL1	-479

---

GO:0071363 cellular response to growth factor stimulus

set	GO:0071363 cellular response to growth factor stimulus
setSize	7
pANOVA	0.00594
s.dist	-0.601
p.adjustANOVA	0.411

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TNFRSF1B	-941
CIB1	-915
RACK1	-782
CTNNB1	-664
THBS1	-481
KLF4	-425
TGFBR2	-74

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TNFRSF1B	-941
CIB1	-915
RACK1	-782
CTNNB1	-664
THBS1	-481
KLF4	-425
TGFBR2	-74

---

GO:1902430 negative regulation of amyloid-beta formation

set	GO:1902430 negative regulation of amyloid-beta formation
setSize	5
pANOVA	0.0226
s.dist	0.59
p.adjustANOVA	0.594

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CLU	841
ROCK1	840
SORL1	671
RTN3	96
RTN4	54

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CLU	841
ROCK1	840
SORL1	671
RTN3	96
RTN4	54

---

GO:1990869 cellular response to chemokine

set	GO:1990869 cellular response to chemokine
setSize	7
pANOVA	0.00888
s.dist	0.572
p.adjustANOVA	0.449

Top enriched genes

Top 20 genes

GeneID	Gene Rank
STK39	830
WNK1	658
DUSP1	623
SH2B3	611
RHOA	460
DOCK8	178
RIPOR2	24

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
STK39	830
WNK1	658
DUSP1	623
SH2B3	611
RHOA	460
DOCK8	178
RIPOR2	24

---

GO:0030071 regulation of mitotic metaphase/anaphase transition

set	GO:0030071 regulation of mitotic metaphase/anaphase transition
setSize	7
pANOVA	0.00923
s.dist	0.569
p.adjustANOVA	0.449

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BRD7	808
ARID1B	564
SMARCC1	500
ACTB	480
SMARCA2	469
ARID2	372
ARID1A	172

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BRD7	808
ARID1B	564
SMARCC1	500
ACTB	480
SMARCA2	469
ARID2	372
ARID1A	172

---

GO:0070316 regulation of G0 to G1 transition

set	GO:0070316 regulation of G0 to G1 transition
setSize	7
pANOVA	0.00923
s.dist	0.569
p.adjustANOVA	0.449

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BRD7	808
ARID1B	564
SMARCC1	500
ACTB	480
SMARCA2	469
ARID2	372
ARID1A	172

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BRD7	808
ARID1B	564
SMARCC1	500
ACTB	480
SMARCA2	469
ARID2	372
ARID1A	172

---

GO:2000819 regulation of nucleotide-excision repair

set	GO:2000819 regulation of nucleotide-excision repair
setSize	7
pANOVA	0.00923
s.dist	0.569
p.adjustANOVA	0.449

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BRD7	808
ARID1B	564
SMARCC1	500
ACTB	480
SMARCA2	469
ARID2	372
ARID1A	172

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BRD7	808
ARID1B	564
SMARCC1	500
ACTB	480
SMARCA2	469
ARID2	372
ARID1A	172

---

GO:0071300 cellular response to retinoic acid

set	GO:0071300 cellular response to retinoic acid
setSize	7
pANOVA	0.0095
s.dist	0.567
p.adjustANOVA	0.449

Top enriched genes

Top 20 genes

GeneID	Gene Rank
YES1	882
LYN	712
NDUFA13	691
ATM	529
CREB1	183
PTK2B	180
GSK3B	174

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
YES1	882
LYN	712
NDUFA13	691
ATM	529
CREB1	183
PTK2B	180
GSK3B	174

---

GO:0031491 nucleosome binding

set	GO:0031491 nucleosome binding
setSize	6
pANOVA	0.0165
s.dist	0.566
p.adjustANOVA	0.554

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NAP1L4	877
HP1BP3	773
ARID1B	564
RNF4	441
ARID1A	172
SUPT6H	43

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NAP1L4	877
HP1BP3	773
ARID1B	564
RNF4	441
ARID1A	172
SUPT6H	43

---

GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity

set	GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity
setSize	5
pANOVA	0.0313
s.dist	0.557
p.adjustANOVA	0.594

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GRB2	869
DOK2	771
SH2B3	611
GAB2	91
PIK3R1	7

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GRB2	869
DOK2	771
SH2B3	611
GAB2	91
PIK3R1	7

---

GO:0050321 tau-protein kinase activity

set	GO:0050321 tau-protein kinase activity
setSize	8
pANOVA	0.0066
s.dist	0.555
p.adjustANOVA	0.411

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ROCK1	840
TAOK1	766
FYN	629
DYRK1A	547
CSNK1D	483
MARK3	345
GSK3B	174
SIK3	-42

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ROCK1	840
TAOK1	766
FYN	629
DYRK1A	547
CSNK1D	483
MARK3	345
GSK3B	174
SIK3	-42

---

GO:0060612 adipose tissue development

set	GO:0060612 adipose tissue development
setSize	5
pANOVA	0.0341
s.dist	0.548
p.adjustANOVA	0.623

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PUM2	790
VPS13B	676
XBP1	619
SPTLC2	382
NAMPT	-159

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PUM2	790
VPS13B	676
XBP1	619
SPTLC2	382
NAMPT	-159

---

GO:0048010 vascular endothelial growth factor receptor signaling pathway

set	GO:0048010 vascular endothelial growth factor receptor signaling pathway
setSize	6
pANOVA	0.0229
s.dist	0.537
p.adjustANOVA	0.594

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FYN	629
XBP1	619
MAPK14	549
MAPKAPK2	508
PAK2	221
PTK2B	180

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FYN	629
XBP1	619
MAPK14	549
MAPKAPK2	508
PAK2	221
PTK2B	180

---

GO:0030414 peptidase inhibitor activity

set	GO:0030414 peptidase inhibitor activity
setSize	6
pANOVA	0.0245
s.dist	-0.531
p.adjustANOVA	0.594

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CST3	-958
TIMP2	-947
CST7	-861
TIMP1	-426
SERPINB1	-108
PARK7	21

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CST3	-958
TIMP2	-947
CST7	-861
TIMP1	-426
SERPINB1	-108
PARK7	21

---

GO:1902894 negative regulation of miRNA transcription

set	GO:1902894 negative regulation of miRNA transcription
setSize	7
pANOVA	0.0153
s.dist	0.53
p.adjustANOVA	0.554

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NCOR1	880
HIF1A	802
SMAD3	703
NFATC3	437
YY1	331
TGFB1	252
NCOR2	-294

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NCOR1	880
HIF1A	802
SMAD3	703
NFATC3	437
YY1	331
TGFB1	252
NCOR2	-294

---

GO:0004857 enzyme inhibitor activity

set	GO:0004857 enzyme inhibitor activity
setSize	7
pANOVA	0.0155
s.dist	0.529
p.adjustANOVA	0.554

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KDM5A	806
PPP1R16B	801
PPP1R12A	737
ATP5IF1	624
DYNLL1	390
TXNIP	-64
FRY	-191

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KDM5A	806
PPP1R16B	801
PPP1R12A	737
ATP5IF1	624
DYNLL1	390
TXNIP	-64
FRY	-191

---

GO:0048147 negative regulation of fibroblast proliferation

set	GO:0048147 negative regulation of fibroblast proliferation
setSize	6
pANOVA	0.0254
s.dist	-0.528
p.adjustANOVA	0.594

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FTH1	-929
IFI30	-914
SOD2	-905
BAX	-680
SKI	-532
GSTP1	700

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FTH1	-929
IFI30	-914
SOD2	-905
BAX	-680
SKI	-532
GSTP1	700

---

GO:2000781 positive regulation of double-strand break repair

set	GO:2000781 positive regulation of double-strand break repair
setSize	8
pANOVA	0.00989
s.dist	0.528
p.adjustANOVA	0.455

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BRD7	808
ARID1B	564
SMARCC1	500
ACTB	480
SMARCA2	469
ARID2	372
ARID1A	172
SPIDR	169

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BRD7	808
ARID1B	564
SMARCC1	500
ACTB	480
SMARCA2	469
ARID2	372
ARID1A	172
SPIDR	169

---

GO:1902459 positive regulation of stem cell population maintenance

set	GO:1902459 positive regulation of stem cell population maintenance
setSize	9
pANOVA	0.00626
s.dist	0.527
p.adjustANOVA	0.411

Top enriched genes

Top 20 genes

GeneID	Gene Rank
OGT	789
NCOA3	565
SMARCC1	500
ACTB	480
ARID4A	476
SMARCA2	469
RBBP4	401
ARID1A	172
ARID4B	118

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
OGT	789
NCOA3	565
SMARCC1	500
ACTB	480
ARID4A	476
SMARCA2	469
RBBP4	401
ARID1A	172
ARID4B	118

---

GO:1902455 negative regulation of stem cell population maintenance

set	GO:1902455 negative regulation of stem cell population maintenance
setSize	5
pANOVA	0.042
s.dist	0.526
p.adjustANOVA	0.65

Top enriched genes

Top 20 genes

GeneID	Gene Rank
OGT	789
ARID4A	476
ZNF706	420
RBBP4	401
ARID4B	118

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
OGT	789
ARID4A	476
ZNF706	420
RBBP4	401
ARID4B	118

---

GO:0001046 core promoter sequence-specific DNA binding

set	GO:0001046 core promoter sequence-specific DNA binding
setSize	6
pANOVA	0.0264
s.dist	0.524
p.adjustANOVA	0.594

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NR3C1	875
NPM1	753
FOXP1	603
KLF10	404
PARK7	21
DRAP1	-22

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NR3C1	875
NPM1	753
FOXP1	603
KLF10	404
PARK7	21
DRAP1	-22

---

GO:0035060 brahma complex

set	GO:0035060 brahma complex
setSize	5
pANOVA	0.0436
s.dist	0.522
p.adjustANOVA	0.65

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ARID1B	564
SMARCC1	500
ACTB	480
SMARCA2	469
ARID1A	172

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ARID1B	564
SMARCC1	500
ACTB	480
SMARCA2	469
ARID1A	172

---

GO:0071564 npBAF complex

set	GO:0071564 npBAF complex
setSize	5
pANOVA	0.0436
s.dist	0.522
p.adjustANOVA	0.65

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ARID1B	564
SMARCC1	500
ACTB	480
SMARCA2	469
ARID1A	172

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ARID1B	564
SMARCC1	500
ACTB	480
SMARCA2	469
ARID1A	172

---

GO:0071565 nBAF complex

set	GO:0071565 nBAF complex
setSize	5
pANOVA	0.0436
s.dist	0.522
p.adjustANOVA	0.65

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ARID1B	564
SMARCC1	500
ACTB	480
SMARCA2	469
ARID1A	172

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ARID1B	564
SMARCC1	500
ACTB	480
SMARCA2	469
ARID1A	172

---

GO:0099170 postsynaptic modulation of chemical synaptic transmission

set	GO:0099170 postsynaptic modulation of chemical synaptic transmission
setSize	6
pANOVA	0.0285
s.dist	-0.517
p.adjustANOVA	0.594

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PPP3R1	-897
BRAF	-810
TRIO	-686
PLCB1	-682
PPP3CA	-306
PTK2B	180

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PPP3R1	-897
BRAF	-810
TRIO	-686
PLCB1	-682
PPP3CA	-306
PTK2B	180

---

GO:0070507 regulation of microtubule cytoskeleton organization

set	GO:0070507 regulation of microtubule cytoskeleton organization
setSize	7
pANOVA	0.018
s.dist	0.517
p.adjustANOVA	0.558

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ROCK1	840
TAOK1	766
PAFAH1B1	735
CLASP1	558
RHOA	460
GSK3B	174
CYLD	-508

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ROCK1	840
TAOK1	766
PAFAH1B1	735
CLASP1	558
RHOA	460
GSK3B	174
CYLD	-508

---

GO:0050811 GABA receptor binding

set	GO:0050811 GABA receptor binding
setSize	5
pANOVA	0.0514
s.dist	-0.504
p.adjustANOVA	0.667

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GABARAPL1	-931
GABARAP	-784
PLCL2	-417
GABARAPL2	-409
PPP2CA	-65

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GABARAPL1	-931
GABARAP	-784
PLCL2	-417
GABARAPL2	-409
PPP2CA	-65

---

GO:0045596 negative regulation of cell differentiation

set	GO:0045596 negative regulation of cell differentiation
setSize	7
pANOVA	0.0235
s.dist	0.495
p.adjustANOVA	0.594

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MAPK1	809
SMARCC1	500
ACTB	480
SMARCA2	469
ANP32B	388
TGFB1	252
RBPJ	-15

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MAPK1	809
SMARCC1	500
ACTB	480
SMARCA2	469
ANP32B	388
TGFB1	252
RBPJ	-15

---

GO:0000421 autophagosome membrane

set	GO:0000421 autophagosome membrane
setSize	13
pANOVA	0.00225
s.dist	-0.491
p.adjustANOVA	0.294

Top enriched genes

Top 20 genes

GeneID	Gene Rank
VMP1	-979
GABARAPL1	-931
ATP6AP2	-838
GABARAP	-784
ULK1	-733
MAP1LC3B	-694
RAB7A	-593
RAB2A	-565
UVRAG	-496
GABARAPL2	-409
RB1CC1	-249
LAMP1	52
CHMP3	627

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
VMP1	-979
GABARAPL1	-931
ATP6AP2	-838
GABARAP	-784
ULK1	-733
MAP1LC3B	-694
RAB7A	-593
RAB2A	-565
UVRAG	-496
GABARAPL2	-409
RB1CC1	-249
LAMP1	52
CHMP3	627

---

GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production

set	GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production
setSize	5
pANOVA	0.0621
s.dist	-0.483
p.adjustANOVA	0.706

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MBP	-949
CD74	-875
MIF	-806
HMGB1	-129
TGFB1	252

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MBP	-949
CD74	-875
MIF	-806
HMGB1	-129
TGFB1	252

---

GO:0042129 regulation of T cell proliferation

set	GO:0042129 regulation of T cell proliferation
setSize	8
pANOVA	0.0186
s.dist	-0.481
p.adjustANOVA	0.566

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BCL6	-984
BID	-946
TNFRSF1B	-941
LGALS3	-854
CTNNB1	-664
SOS1	-517
SOS2	435
RAC2	475

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BCL6	-984
BID	-946
TNFRSF1B	-941
LGALS3	-854
CTNNB1	-664
SOS1	-517
SOS2	435
RAC2	475

---

GO:0001664 G protein-coupled receptor binding

set	GO:0001664 G protein-coupled receptor binding
setSize	14
pANOVA	0.00193
s.dist	0.48
p.adjustANOVA	0.294

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HBA1	884
GRK2	851
ARRB2	850
GNAQ	847
ARHGEF1	803
FYN	629
HSPA8	474
GRK3	429
FLNA	378
USP33	328
GNAI2	280
DNAJA1	211
FCN1	-695
FPR1	-727

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HBA1	884
GRK2	851
ARRB2	850
GNAQ	847
ARHGEF1	803
FYN	629
HSPA8	474
GRK3	429
FLNA	378
USP33	328
GNAI2	280
DNAJA1	211
FCN1	-695
FPR1	-727

---

GO:0006622 protein targeting to lysosome

set	GO:0006622 protein targeting to lysosome
setSize	6
pANOVA	0.0437
s.dist	0.476
p.adjustANOVA	0.65

Top enriched genes

Top 20 genes

GeneID	Gene Rank
AP3B1	874
NCOA4	772
SORL1	671
LAPTM5	391
VPS53	251
RAB7A	-593

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
AP3B1	874
NCOA4	772
SORL1	671
LAPTM5	391
VPS53	251
RAB7A	-593

---

GO:0031589 cell-substrate adhesion

set	GO:0031589 cell-substrate adhesion
setSize	5
pANOVA	0.0657
s.dist	0.476
p.adjustANOVA	0.708

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ITGB1	651
PRKX	640
PRKCE	286
CORO1A	285
MYO1G	109

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ITGB1	651
PRKX	640
PRKCE	286
CORO1A	285
MYO1G	109

---

GO:0045953 negative regulation of natural killer cell mediated cytotoxicity

set	GO:0045953 negative regulation of natural killer cell mediated cytotoxicity
setSize	5
pANOVA	0.0657
s.dist	0.476
p.adjustANOVA	0.708

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GRB2	869
ARRB2	850
HLA-E	491
HLA-F	-45
INPP5D	-194

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GRB2	869
ARRB2	850
HLA-E	491
HLA-F	-45
INPP5D	-194

---

GO:0051893 regulation of focal adhesion assembly

set	GO:0051893 regulation of focal adhesion assembly
setSize	8
pANOVA	0.0205
s.dist	0.474
p.adjustANOVA	0.594

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ROCK1	840
MACF1	792
CLASP1	558
VCL	511
RHOA	460
PTPRA	71
TLN1	12
ACTG1	-111

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ROCK1	840
MACF1	792
CLASP1	558
VCL	511
RHOA	460
PTPRA	71
TLN1	12
ACTG1	-111

---

GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway

set	GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
setSize	8
pANOVA	0.0207
s.dist	0.473
p.adjustANOVA	0.594

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GNAQ	847
GNAS	710
PRKAR2A	537
PRKAR2B	371
GNAI2	280
ADGRE5	224
GNA13	195
PF4	-37

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GNAQ	847
GNAS	710
PRKAR2A	537
PRKAR2B	371
GNAI2	280
ADGRE5	224
GNA13	195
PF4	-37

---

GO:0030971 receptor tyrosine kinase binding

set	GO:0030971 receptor tyrosine kinase binding
setSize	6
pANOVA	0.0474
s.dist	-0.468
p.adjustANOVA	0.667

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SQSTM1	-952
PTPN2	-813
RACK1	-782
DAZAP2	-594
ITGAX	-527
CBLB	741

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SQSTM1	-952
PTPN2	-813
RACK1	-782
DAZAP2	-594
ITGAX	-527
CBLB	741

---

GO:0035580 specific granule lumen

set	GO:0035580 specific granule lumen
setSize	11
pANOVA	0.00763
s.dist	-0.466
p.adjustANOVA	0.433

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LYZ	-983
TIMP2	-947
DOCK2	-877
NFKB1	-785
CTSZ	-757
RAB27A	-746
CFP	-511
PTPN6	-186
CTSD	-52
B2M	6
VCL	511

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LYZ	-983
TIMP2	-947
DOCK2	-877
NFKB1	-785
CTSZ	-757
RAB27A	-746
CFP	-511
PTPN6	-186
CTSD	-52
B2M	6
VCL	511

---

GO:0031643 positive regulation of myelination

set	GO:0031643 positive regulation of myelination
setSize	6
pANOVA	0.0503
s.dist	-0.462
p.adjustANOVA	0.667

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TNFRSF1B	-941
CST7	-861
DICER1	-781
ITGAX	-527
RNF10	-57
QKI	274

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TNFRSF1B	-941
CST7	-861
DICER1	-781
ITGAX	-527
RNF10	-57
QKI	274

---

GO:1901798 positive regulation of signal transduction by p53 class mediator

set	GO:1901798 positive regulation of signal transduction by p53 class mediator
setSize	5
pANOVA	0.0746
s.dist	-0.461
p.adjustANOVA	0.743

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL23	-950
RPL37	-777
RPL11	-630
RPS20	-31
RPS15	-19

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL23	-950
RPL37	-777
RPL11	-630
RPS20	-31
RPS15	-19

---

GO:0034142 toll-like receptor 4 signaling pathway

set	GO:0034142 toll-like receptor 4 signaling pathway
setSize	7
pANOVA	0.0351
s.dist	0.461
p.adjustANOVA	0.626

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LYN	712
NFKBIA	615
TBK1	594
TRAF3	518
RIPK2	415
CD14	273
PIK3AP1	-470

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LYN	712
NFKBIA	615
TBK1	594
TRAF3	518
RIPK2	415
CD14	273
PIK3AP1	-470

---

GO:0014044 Schwann cell development

set	GO:0014044 Schwann cell development
setSize	5
pANOVA	0.0757
s.dist	0.459
p.adjustANOVA	0.743

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GRB2	869
MAPK1	809
MAP2K1	620
MAP2K2	113
SOS1	-517

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GRB2	869
MAPK1	809
MAP2K1	620
MAP2K2	113
SOS1	-517

---

Network diagram

Only used for one-dimensional analysis.

Here, the network diagram is used to depict the similarity between some of the top ranked gene sets. It makes separate charts for up and downregulated sets. It works best when prioritisation is done by effect size during the mitch_calc() step. By default, we only show the top 20 genes, but you can use the networkplot() command yourself with other options. See ?networkplot for more detail. There is an element of stochasticity with regard to the network projection, so if you see a lot of overlapping labels or labels getting cut off, you could repeat the chart generation until you get a nice layout. See ?networkplot for more detail.

Below the network diagrams, you will see lists of genes that make up the up and downregulated sets respectively. For upregulated genes the score needs to be >2 and for downregulated genes it needs to be < -2. This is to remove genes that have uninteresting differential expression and do not contribute enrichment.

if (d==1) {
  networkplot(eres=res,FDR=0.05,n_sets=20)
  network_genes(eres=res,FDR=0.05,n_sets=20)
} else {
 message("Network charts only generated in one-dimensional analysis.")
}

## Can't plot upregulated sets. Fewer than 5 found.

## No significant upregulated sets to show.

## [[1]]
## [[1]]$`DOWN genesets.GO:0002181 cytoplasmic translation`
##  [1] "RPL23"   "RPS24"   "RPS19"   "RPS26"   "RPL12"   "RPL21"   "RPL19"  
##  [8] "RPL32"   "RPL29"   "RPL10"   "RPL23A"  "RPL38"   "RPL4"    "RPL27A" 
## [15] "RPL7A"   "RACK1"   "RPL37"   "RPS15A"  "RPL30"   "RPS4X"   "RPLP1"  
## [22] "RPL5"    "RPL17"   "RPL34"   "RPS13"   "RPL11"   "RPL18A"  "RPL3"   
## [29] "RPS27"   "RPS5"    "RPL13A"  "RPL36"   "RPS9"    "RPS14"   "RPS23"  
## [36] "RPS10"   "RPS3"    "RPLP0"   "RPL18"   "RPL26"   "RPS21"   "RPL35A" 
## [43] "RPL6"    "RPL15"   "RPL31"   "RPL24"   "RPL13"   "RPL27"   "RPL39"  
## [50] "RPS16"   "RPS25"   "RPS3A"   "RPL10A"  "RPS2"    "RPS6"    "RPL8"   
## [57] "RPSA"    "RPS18"   "RPL22L1" "RPLP2"   "RPS27A"  "RPL36A"  "RPL22"  
## [64] "RPL28"   "FAU"     "RPS7"    "RPS28"   "RPS11"   "RPL37A"  "RPL7"   
## [71] "RPL41"   "RPS29"   "RPL35"   "RPS8"    "RPL9"    "RPS12"   "RPS17"  
## [78] "RPS20"   "RPS15"   "RPL14"   "UBA52"  
## 
## [[1]]$`DOWN genesets.GO:0003735 structural constituent of ribosome`
##  [1] "RPL23"   "RPS24"   "RPS19"   "RPS26"   "RPL12"   "RPL21"   "RPL19"  
##  [8] "RPL32"   "RPL29"   "RPL10"   "RPL23A"  "RPL38"   "RPL4"    "RPL27A" 
## [15] "RPL7A"   "RPL37"   "RPS27L"  "RPS15A"  "RPL30"   "RPS4X"   "RPLP1"  
## [22] "MRPS21"  "RPL5"    "RPL17"   "RPL34"   "RPS13"   "RPL11"   "RPL18A" 
## [29] "RPL3"    "RPS27"   "RPS5"    "RPL13A"  "RPL36"   "RPL36AL" "RPS9"   
## [36] "RPS14"   "RPS23"   "RPS10"   "RPS3"    "RPLP0"   "RPL18"   "RPL26"  
## [43] "RPS4Y1"  "RPS21"   "RPL35A"  "RPL6"    "RPL15"   "RPL31"   "RPL24"  
## [50] "RPL13"   "RPL27"   "RPL39"   "RPS16"   "RPS25"   "RPS3A"   "RPL10A" 
## [57] "RPS2"    "RPS6"    "RPL8"    "RPSA"    "RPS18"   "RPL22L1" "RPLP2"  
## [64] "RSL24D1" "RPS27A"  "RPL36A"  "RPL22"   "RPL28"   "FAU"     "RPS7"   
## [71] "RPS28"   "RPS11"   "RPL37A"  "RPL7"    "RPL41"   "RPS29"   "RPL35"  
## [78] "RPS8"    "RPL9"    "RPS12"   "RPS17"   "RPS20"   "MRPL33"  "RPS15"  
## [85] "RPL14"   "UBA52"  
## 
## [[1]]$`DOWN genesets.GO:0006412 translation`
##  [1] "RPL23"   "RPS24"   "RPS19"   "RPS26"   "RPL12"   "RPL21"   "RPL19"  
##  [8] "RPL32"   "RPL29"   "RPL10"   "RPL23A"  "CPEB4"   "RPL38"   "RPL4"   
## [15] "RPL27A"  "RPL7A"   "RPL37"   "RPS27L"  "RPS15A"  "RPL30"   "RPS4X"  
## [22] "RPLP1"   "MRPS21"  "RPL5"    "RPL17"   "RPL34"   "RPS13"   "EEF1A1" 
## [29] "RPL11"   "RRBP1"   "RPL18A"  "PAIP2"   "RPL3"    "RPS27"   "RPS5"   
## [36] "RPL13A"  "RPL36"   "RPL36AL" "RPS9"    "NACA"    "RPS14"   "RPS23"  
## [43] "RPS10"   "RPS3"    "RPLP0"   "RPL18"   "ABCF1"   "RPL26"   "RPS4Y1" 
## [50] "RPS21"   "RPL35A"  "RPL6"    "RPL15"   "RPL31"   "RPL24"   "RPL13"  
## [57] "RPL27"   "RPL39"   "RPS16"   "RPS25"   "RPS3A"   "RPL10A"  "RPS2"   
## [64] "RPS6"    "RPL8"    "RPSA"    "RPS18"   "RPLP2"   "RSL24D1" "RPS27A" 
## [71] "RPL36A"  "RPL22"   "RPL28"   "FAU"     "RPS7"    "RPS28"   "RPS11"  
## [78] "RPL37A"  "RPL7"    "RPL41"   "RPS29"   "RPL35"   "RPS8"    "RPL9"   
## [85] "RPS12"   "RPS17"   "RPS20"   "RPS15"   "RPL14"   "UBA52"  
## 
## [[1]]$`DOWN genesets.GO:0022625 cytosolic large ribosomal subunit`
##  [1] "RPL23"   "RPL12"   "RPL21"   "RPL19"   "RPL32"   "RPL29"   "RPL10"  
##  [8] "RPL23A"  "RPL38"   "RPL4"    "RPL27A"  "RPL7A"   "RPL37"   "RPL30"  
## [15] "RPLP1"   "RPL5"    "RPL17"   "RPL34"   "RPL11"   "RPL18A"  "RPL3"   
## [22] "RPL13A"  "RPL36"   "RPL36AL" "RPLP0"   "RPL18"   "RPL26"   "RPL35A" 
## [29] "RPL6"    "RPL15"   "RPL31"   "RPL24"   "RPL13"   "RPL27"   "RPL39"  
## [36] "RPL10A"  "RPL8"    "RPLP2"   "RPL36A"  "RPL22"   "RPL28"   "RPL37A" 
## [43] "RPL7"    "RPL41"   "RPL35"   "RPL9"    "RPL14"   "UBA52"  
## 
## [[1]]$`DOWN genesets.GO:0022626 cytosolic ribosome`
##  [1] "RPL23"  "RPS24"  "RPS19"  "RPL12"  "NEMF"   "RPL21"  "RPL19"  "RPL32" 
##  [9] "RPL29"  "RPL10"  "RPL23A" "RPL38"  "RPL4"   "RPL27A" "RPL7A"  "RPL37" 
## [17] "RPS15A" "RPL30"  "RPS4X"  "RPLP1"  "RPL5"   "RPL17"  "RPL34"  "RPS13" 
## [25] "EEF1A1" "RPL11"  "RPL18A" "RPL3"   "RPS27"  "RPS5"   "RPL13A" "RPL36" 
## [33] "RPS9"   "RPS14"  "RPS23"  "RPS10"  "RPS3"   "RPLP0"  "RPL18"  "RPL26" 
## [41] "RPS21"  "RPL35A" "RPL6"   "RPL15"  "RPL31"  "RPL24"  "RPL13"  "RPL27" 
## [49] "RPL39"  "RPS16"  "RPS25"  "RPS3A"  "RPL10A" "RPS2"   "RPS6"   "RPL8"  
## [57] "RPSA"   "RPS18"  "RPS27A" "RPL36A" "RPL22"  "RPL28"  "FAU"    "RPS7"  
## [65] "RPS11"  "RPL37A" "RPL7"   "RPL35"  "RPS8"   "RPL9"   "RPS12"  "RNF10" 
## [73] "RPS17"  "ETF1"   "RPS20"  "RPS15"  "RPL14"  "UBA52"

Session information

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.5.0 (2025-04-11)
## Platform: x86_64-pc-linux-gnu
## Running under: Ubuntu 22.04.5 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.10.0 
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.10.0  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Australia/Melbourne
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] gtools_3.9.5                future_1.40.0              
##  [3] reshape2_1.4.4              dplyr_1.1.4                
##  [5] eulerr_7.0.2                network_1.19.0             
##  [7] gplots_3.2.0                kableExtra_1.4.0           
##  [9] limma_3.64.0                mitch_1.20.0               
## [11] DESeq2_1.48.0               muscat_1.22.0              
## [13] beeswarm_0.4.0              stringi_1.8.7              
## [15] SingleCellExperiment_1.30.0 SummarizedExperiment_1.38.0
## [17] Biobase_2.68.0              GenomicRanges_1.60.0       
## [19] GenomeInfoDb_1.44.0         IRanges_2.42.0             
## [21] S4Vectors_0.46.0            BiocGenerics_0.54.0        
## [23] generics_0.1.3              MatrixGenerics_1.20.0      
## [25] matrixStats_1.5.0           hdf5r_1.3.12               
## [27] Seurat_5.3.0                SeuratObject_5.1.0         
## [29] sp_2.2-0                    plyr_1.8.9                 
## 
## loaded via a namespace (and not attached):
##   [1] spatstat.sparse_3.1-0    bitops_1.0-9             httr_1.4.7              
##   [4] RColorBrewer_1.1-3       doParallel_1.0.17        numDeriv_2016.8-1.1     
##   [7] tools_4.5.0              sctransform_0.4.1        backports_1.5.0         
##  [10] R6_2.6.1                 lazyeval_0.2.2           uwot_0.2.3              
##  [13] mgcv_1.9-3               GetoptLong_1.0.5         withr_3.0.2             
##  [16] GGally_2.2.1             prettyunits_1.2.0        gridExtra_2.3           
##  [19] progressr_0.15.1         cli_3.6.5                spatstat.explore_3.4-2  
##  [22] fastDummies_1.7.5        labeling_0.4.3           sass_0.4.10             
##  [25] mvtnorm_1.3-3            spatstat.data_3.1-6      blme_1.0-6              
##  [28] ggridges_0.5.6           pbapply_1.7-2            systemfonts_1.2.2       
##  [31] svglite_2.1.3            dichromat_2.0-0.1        scater_1.36.0           
##  [34] parallelly_1.43.0        rstudioapi_0.17.1        shape_1.4.6.1           
##  [37] ica_1.0-3                spatstat.random_3.3-3    Matrix_1.7-3            
##  [40] ggbeeswarm_0.7.2         abind_1.4-8              lifecycle_1.0.4         
##  [43] yaml_2.3.10              edgeR_4.6.1              SparseArray_1.8.0       
##  [46] Rtsne_0.17               grid_4.5.0               promises_1.3.2          
##  [49] crayon_1.5.3             miniUI_0.1.2             lattice_0.22-7          
##  [52] echarts4r_0.4.5          beachmat_2.24.0          cowplot_1.1.3           
##  [55] pillar_1.10.2            knitr_1.50               ComplexHeatmap_2.24.0   
##  [58] rjson_0.2.23             boot_1.3-31              corpcor_1.6.10          
##  [61] future.apply_1.11.3      codetools_0.2-20         glue_1.8.0              
##  [64] spatstat.univar_3.1-2    data.table_1.17.0        vctrs_0.6.5             
##  [67] png_0.1-8                spam_2.11-1              Rdpack_2.6.4            
##  [70] gtable_0.3.6             cachem_1.1.0             xfun_0.52               
##  [73] rbibutils_2.3            S4Arrays_1.8.0           mime_0.13               
##  [76] coda_0.19-4.1            reformulas_0.4.0         survival_3.8-3          
##  [79] iterators_1.0.14         statmod_1.5.0            fitdistrplus_1.2-2      
##  [82] ROCR_1.0-11              nlme_3.1-168             pbkrtest_0.5.4          
##  [85] bit64_4.6.0-1            progress_1.2.3           EnvStats_3.1.0          
##  [88] RcppAnnoy_0.0.22         bslib_0.9.0              TMB_1.9.17              
##  [91] irlba_2.3.5.1            vipor_0.4.7              KernSmooth_2.23-26      
##  [94] colorspace_2.1-1         ggrastr_1.0.2            tidyselect_1.2.1        
##  [97] bit_4.6.0                compiler_4.5.0           BiocNeighbors_2.2.0     
## [100] xml2_1.3.8               DelayedArray_0.34.1      plotly_4.10.4           
## [103] scales_1.4.0             caTools_1.18.3           remaCor_0.0.18          
## [106] lmtest_0.9-40            stringr_1.5.1            digest_0.6.37           
## [109] goftest_1.2-3            spatstat.utils_3.1-3     minqa_1.2.8             
## [112] variancePartition_1.38.0 rmarkdown_2.29           aod_1.3.3               
## [115] XVector_0.48.0           RhpcBLASctl_0.23-42      htmltools_0.5.8.1       
## [118] pkgconfig_2.0.3          lme4_1.1-37              fastmap_1.2.0           
## [121] rlang_1.1.6              GlobalOptions_0.1.2      htmlwidgets_1.6.4       
## [124] UCSC.utils_1.4.0         shiny_1.10.0             farver_2.1.2            
## [127] jquerylib_0.1.4          zoo_1.8-14               jsonlite_2.0.0          
## [130] statnet.common_4.11.0    BiocParallel_1.42.0      BiocSingular_1.24.0     
## [133] magrittr_2.0.3           scuttle_1.18.0           GenomeInfoDbData_1.2.14 
## [136] dotCall64_1.2            patchwork_1.3.0          Rcpp_1.0.14             
## [139] viridis_0.6.5            reticulate_1.42.0        MASS_7.3-65             
## [142] ggstats_0.9.0            listenv_0.9.1            ggrepel_0.9.6           
## [145] deldir_2.0-4             splines_4.5.0            tensor_1.5              
## [148] hms_1.1.3                circlize_0.4.16          locfit_1.5-9.12         
## [151] igraph_2.1.4             spatstat.geom_3.3-6      RcppHNSW_0.6.0          
## [154] ScaledMatrix_1.16.0      evaluate_1.0.3           nloptr_2.2.1            
## [157] foreach_1.5.2            httpuv_1.6.16            RANN_2.6.2              
## [160] tidyr_1.3.1              purrr_1.0.4              polyclip_1.10-7         
## [163] clue_0.3-66              scattermore_1.2          ggplot2_3.5.2           
## [166] rsvd_1.0.5               broom_1.0.8              xtable_1.8-4            
## [169] fANCOVA_0.6-1            RSpectra_0.16-2          later_1.4.2             
## [172] viridisLite_0.4.2        tibble_3.2.1             lmerTest_3.1-3          
## [175] glmmTMB_1.1.11           cluster_2.1.8.1          globals_0.17.0

END of report