date generated: 2021-04-20

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

##                    x
## A1BG      0.23019048
## A1BG-AS1  0.62211022
## A1CF      0.68373998
## A2M      -0.03980079
## A2M-AS1  -0.04056761
## A2ML1     0.91485083

Here are some metrics about the input data profile:

Profile metrics
Profile metrics
num_genesets 2408
num_genes_in_profile 21631
duplicated_genes_present 0
num_profile_genes_in_sets 8410
num_profile_genes_not_in_sets 13221

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt

Gene sets metrics
Gene sets metrics
num_genesets 2408
num_genesets_excluded 1045
num_genesets_included 1363

Differential pathway expression


Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 100 gene sets

set setSize pANOVA s.dist p.adjustANOVA
rRNA processing in the nucleus and cytosol 190 6.06e-45 -0.5900 8.26e-42
rRNA processing 217 4.38e-44 -0.5470 2.99e-41
Neutrophil degranulation 457 3.04e-43 0.3760 1.16e-40
Major pathway of rRNA processing in the nucleolus and cytosol 180 3.41e-43 -0.5940 1.16e-40
Metabolism of RNA 685 1.57e-38 -0.2900 4.27e-36
Translation 295 4.36e-32 -0.3980 9.91e-30
Formation of a pool of free 40S subunits 100 5.67e-32 -0.6800 1.10e-29
Eukaryotic Translation Elongation 93 7.89e-32 -0.7030 1.34e-29
Peptide chain elongation 88 2.46e-30 -0.7050 3.72e-28
GTP hydrolysis and joining of the 60S ribosomal subunit 111 8.89e-30 -0.6220 1.10e-27
Selenocysteine synthesis 92 9.58e-30 -0.6820 1.10e-27
L13a-mediated translational silencing of Ceruloplasmin expression 110 9.65e-30 -0.6240 1.10e-27
Eukaryotic Translation Termination 92 2.59e-29 -0.6770 2.72e-27
Viral mRNA Translation 88 1.67e-28 -0.6820 1.62e-26
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 94 3.69e-28 -0.6560 3.35e-26
Influenza Viral RNA Transcription and Replication 135 4.19e-28 -0.5470 3.57e-26
Cap-dependent Translation Initiation 118 5.14e-28 -0.5840 3.89e-26
Eukaryotic Translation Initiation 118 5.14e-28 -0.5840 3.89e-26
Response of EIF2AK4 (GCN2) to amino acid deficiency 100 9.21e-28 -0.6310 6.61e-26
Gene expression (Transcription) 1323 4.44e-27 -0.1760 3.02e-25
Influenza Infection 154 5.85e-27 -0.5010 3.80e-25
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 114 1.01e-25 -0.5680 5.96e-24
Nonsense-Mediated Decay (NMD) 114 1.01e-25 -0.5680 5.96e-24
Innate Immune System 966 2.58e-25 0.1970 1.47e-23
Selenoamino acid metabolism 114 1.10e-24 -0.5550 6.01e-23
SRP-dependent cotranslational protein targeting to membrane 111 1.26e-24 -0.5620 6.59e-23
RNA Polymerase II Transcription 1196 4.47e-20 -0.1570 2.26e-18
Generic Transcription Pathway 1077 5.34e-20 -0.1650 2.60e-18
Formation of the ternary complex, and subsequently, the 43S complex 51 2.80e-14 -0.6150 1.31e-12
Regulation of expression of SLITs and ROBOs 159 3.68e-14 -0.3480 1.67e-12
rRNA modification in the nucleus and cytosol 59 1.02e-13 -0.5600 4.48e-12
Translation initiation complex formation 58 6.84e-13 -0.5450 2.91e-11
Membrane Trafficking 558 8.92e-13 0.1770 3.68e-11
Ribosomal scanning and start codon recognition 58 1.10e-12 -0.5400 4.39e-11
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 59 2.07e-12 -0.5290 8.07e-11
Signaling by ROBO receptors 199 8.42e-11 -0.2670 3.19e-09
Cell Cycle 623 8.80e-11 -0.1520 3.24e-09
tRNA processing 134 1.13e-09 -0.3050 4.06e-08
Metabolism of amino acids and derivatives 324 1.23e-09 -0.1960 4.29e-08
Processing of Capped Intron-Containing Pre-mRNA 238 6.69e-09 -0.2180 2.28e-07
CD22 mediated BCR regulation 59 6.94e-09 -0.4360 2.31e-07
Activation of the pre-replicative complex 32 1.20e-08 -0.5820 3.89e-07
Translocation of ZAP-70 to Immunological synapse 24 1.86e-08 -0.6630 5.90e-07
Scavenging of heme from plasma 71 2.01e-08 -0.3850 6.23e-07
Classical antibody-mediated complement activation 69 2.98e-08 -0.3860 9.02e-07
Cell Cycle, Mitotic 501 4.02e-08 -0.1430 1.19e-06
Immune System 1892 4.20e-08 0.0762 1.22e-06
FCGR activation 76 5.44e-08 -0.3610 1.54e-06
FCERI mediated Ca+2 mobilization 89 5.89e-08 -0.3320 1.64e-06
Creation of C4 and C2 activators 71 9.77e-08 -0.3660 2.66e-06
Extension of Telomeres 51 1.09e-07 -0.4300 2.87e-06
Metabolism of non-coding RNA 53 1.11e-07 -0.4210 2.87e-06
snRNP Assembly 53 1.11e-07 -0.4210 2.87e-06
DNA strand elongation 32 1.35e-07 -0.5380 3.40e-06
Activation of ATR in response to replication stress 37 1.91e-07 -0.4950 4.72e-06
Role of LAT2/NTAL/LAB on calcium mobilization 74 4.04e-07 -0.3410 9.84e-06
Chromosome Maintenance 105 5.23e-07 -0.2830 1.25e-05
Metabolism of lipids 626 7.53e-07 0.1160 1.77e-05
Telomere C-strand (Lagging Strand) Synthesis 34 7.85e-07 -0.4890 1.81e-05
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 84 9.73e-07 -0.3090 2.21e-05
Role of phospholipids in phagocytosis 88 1.17e-06 -0.3000 2.61e-05
Vesicle-mediated transport 648 1.24e-06 0.1120 2.72e-05
Generation of second messenger molecules 38 1.37e-06 -0.4530 2.92e-05
PD-1 signaling 28 1.37e-06 -0.5270 2.92e-05
mRNA Splicing - Major Pathway 179 1.67e-06 -0.2080 3.49e-05
tRNA processing in the nucleus 59 1.89e-06 -0.3590 3.90e-05
ER to Golgi Anterograde Transport 129 2.04e-06 0.2420 4.16e-05
Initial triggering of complement 78 2.23e-06 -0.3100 4.48e-05
mRNA Splicing 187 2.51e-06 -0.2000 4.96e-05
Mitotic Prometaphase 184 2.79e-06 -0.2000 5.44e-05
Interactions of Vpr with host cellular proteins 37 3.55e-06 -0.4400 6.81e-05
FCGR3A-mediated IL10 synthesis 99 3.84e-06 -0.2690 7.27e-05
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 182 4.09e-06 -0.1980 7.55e-05
Post-translational protein phosphorylation 70 4.10e-06 0.3180 7.55e-05
Interactions of Rev with host cellular proteins 37 4.77e-06 -0.4350 8.66e-05
S Phase 160 5.65e-06 -0.2080 1.01e-04
Mitochondrial translation elongation 91 6.17e-06 -0.2740 1.09e-04
IRAK4 deficiency (TLR2/4) 10 6.62e-06 0.8230 1.14e-04
MyD88 deficiency (TLR2/4) 10 6.62e-06 0.8230 1.14e-04
DNA Repair 289 6.78e-06 -0.1540 1.16e-04
Binding and Uptake of Ligands by Scavenger Receptors 92 8.56e-06 -0.2680 1.44e-04
Rev-mediated nuclear export of HIV RNA 35 1.17e-05 -0.4280 1.93e-04
Mitochondrial translation termination 91 1.17e-05 -0.2660 1.93e-04
Clathrin-mediated endocytosis 127 1.21e-05 0.2250 1.96e-04
EPH-Ephrin signaling 79 1.22e-05 0.2850 1.96e-04
Mitochondrial translation 97 1.26e-05 -0.2570 1.99e-04
Mitochondrial translation initiation 91 1.48e-05 -0.2630 2.31e-04
Vpr-mediated nuclear import of PICs 34 1.50e-05 -0.4290 2.32e-04
Antigen processing-Cross presentation 97 1.74e-05 0.2520 2.66e-04
Phosphorylation of CD3 and TCR zeta chains 27 1.96e-05 -0.4750 2.96e-04
RHO GTPases Activate WASPs and WAVEs 35 2.11e-05 0.4150 3.16e-04
trans-Golgi Network Vesicle Budding 69 2.39e-05 0.2940 3.53e-04
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 81 2.53e-05 0.2710 3.71e-04
FCERI mediated MAPK activation 90 2.82e-05 -0.2550 4.09e-04
Nuclear import of Rev protein 34 2.89e-05 -0.4140 4.14e-04
Detoxification of Reactive Oxygen Species 32 3.05e-05 0.4260 4.33e-04
COPI-mediated anterograde transport 78 3.17e-05 0.2720 4.45e-04
NS1 Mediated Effects on Host Pathways 40 3.22e-05 -0.3800 4.48e-04
Signaling by Receptor Tyrosine Kinases 414 3.90e-05 0.1180 5.36e-04
SUMOylation 165 5.95e-05 -0.1810 8.07e-04


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pANOVA s.dist p.adjustANOVA
rRNA processing in the nucleus and cytosol 190 6.06e-45 -5.90e-01 8.26e-42
rRNA processing 217 4.38e-44 -5.47e-01 2.99e-41
Neutrophil degranulation 457 3.04e-43 3.76e-01 1.16e-40
Major pathway of rRNA processing in the nucleolus and cytosol 180 3.41e-43 -5.94e-01 1.16e-40
Metabolism of RNA 685 1.57e-38 -2.90e-01 4.27e-36
Translation 295 4.36e-32 -3.98e-01 9.91e-30
Formation of a pool of free 40S subunits 100 5.67e-32 -6.80e-01 1.10e-29
Eukaryotic Translation Elongation 93 7.89e-32 -7.03e-01 1.34e-29
Peptide chain elongation 88 2.46e-30 -7.05e-01 3.72e-28
GTP hydrolysis and joining of the 60S ribosomal subunit 111 8.89e-30 -6.22e-01 1.10e-27
Selenocysteine synthesis 92 9.58e-30 -6.82e-01 1.10e-27
L13a-mediated translational silencing of Ceruloplasmin expression 110 9.65e-30 -6.24e-01 1.10e-27
Eukaryotic Translation Termination 92 2.59e-29 -6.77e-01 2.72e-27
Viral mRNA Translation 88 1.67e-28 -6.82e-01 1.62e-26
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 94 3.69e-28 -6.56e-01 3.35e-26
Influenza Viral RNA Transcription and Replication 135 4.19e-28 -5.47e-01 3.57e-26
Cap-dependent Translation Initiation 118 5.14e-28 -5.84e-01 3.89e-26
Eukaryotic Translation Initiation 118 5.14e-28 -5.84e-01 3.89e-26
Response of EIF2AK4 (GCN2) to amino acid deficiency 100 9.21e-28 -6.31e-01 6.61e-26
Gene expression (Transcription) 1323 4.44e-27 -1.76e-01 3.02e-25
Influenza Infection 154 5.85e-27 -5.01e-01 3.80e-25
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 114 1.01e-25 -5.68e-01 5.96e-24
Nonsense-Mediated Decay (NMD) 114 1.01e-25 -5.68e-01 5.96e-24
Innate Immune System 966 2.58e-25 1.97e-01 1.47e-23
Selenoamino acid metabolism 114 1.10e-24 -5.55e-01 6.01e-23
SRP-dependent cotranslational protein targeting to membrane 111 1.26e-24 -5.62e-01 6.59e-23
RNA Polymerase II Transcription 1196 4.47e-20 -1.57e-01 2.26e-18
Generic Transcription Pathway 1077 5.34e-20 -1.65e-01 2.60e-18
Formation of the ternary complex, and subsequently, the 43S complex 51 2.80e-14 -6.15e-01 1.31e-12
Regulation of expression of SLITs and ROBOs 159 3.68e-14 -3.48e-01 1.67e-12
rRNA modification in the nucleus and cytosol 59 1.02e-13 -5.60e-01 4.48e-12
Translation initiation complex formation 58 6.84e-13 -5.45e-01 2.91e-11
Membrane Trafficking 558 8.92e-13 1.77e-01 3.68e-11
Ribosomal scanning and start codon recognition 58 1.10e-12 -5.40e-01 4.39e-11
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 59 2.07e-12 -5.29e-01 8.07e-11
Signaling by ROBO receptors 199 8.42e-11 -2.67e-01 3.19e-09
Cell Cycle 623 8.80e-11 -1.52e-01 3.24e-09
tRNA processing 134 1.13e-09 -3.05e-01 4.06e-08
Metabolism of amino acids and derivatives 324 1.23e-09 -1.96e-01 4.29e-08
Processing of Capped Intron-Containing Pre-mRNA 238 6.69e-09 -2.18e-01 2.28e-07
CD22 mediated BCR regulation 59 6.94e-09 -4.36e-01 2.31e-07
Activation of the pre-replicative complex 32 1.20e-08 -5.82e-01 3.89e-07
Translocation of ZAP-70 to Immunological synapse 24 1.86e-08 -6.63e-01 5.90e-07
Scavenging of heme from plasma 71 2.01e-08 -3.85e-01 6.23e-07
Classical antibody-mediated complement activation 69 2.98e-08 -3.86e-01 9.02e-07
Cell Cycle, Mitotic 501 4.02e-08 -1.43e-01 1.19e-06
Immune System 1892 4.20e-08 7.62e-02 1.22e-06
FCGR activation 76 5.44e-08 -3.61e-01 1.54e-06
FCERI mediated Ca+2 mobilization 89 5.89e-08 -3.32e-01 1.64e-06
Creation of C4 and C2 activators 71 9.77e-08 -3.66e-01 2.66e-06
Extension of Telomeres 51 1.09e-07 -4.30e-01 2.87e-06
Metabolism of non-coding RNA 53 1.11e-07 -4.21e-01 2.87e-06
snRNP Assembly 53 1.11e-07 -4.21e-01 2.87e-06
DNA strand elongation 32 1.35e-07 -5.38e-01 3.40e-06
Activation of ATR in response to replication stress 37 1.91e-07 -4.95e-01 4.72e-06
Role of LAT2/NTAL/LAB on calcium mobilization 74 4.04e-07 -3.41e-01 9.84e-06
Chromosome Maintenance 105 5.23e-07 -2.83e-01 1.25e-05
Metabolism of lipids 626 7.53e-07 1.16e-01 1.77e-05
Telomere C-strand (Lagging Strand) Synthesis 34 7.85e-07 -4.89e-01 1.81e-05
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 84 9.73e-07 -3.09e-01 2.21e-05
Role of phospholipids in phagocytosis 88 1.17e-06 -3.00e-01 2.61e-05
Vesicle-mediated transport 648 1.24e-06 1.12e-01 2.72e-05
Generation of second messenger molecules 38 1.37e-06 -4.53e-01 2.92e-05
PD-1 signaling 28 1.37e-06 -5.27e-01 2.92e-05
mRNA Splicing - Major Pathway 179 1.67e-06 -2.08e-01 3.49e-05
tRNA processing in the nucleus 59 1.89e-06 -3.59e-01 3.90e-05
ER to Golgi Anterograde Transport 129 2.04e-06 2.42e-01 4.16e-05
Initial triggering of complement 78 2.23e-06 -3.10e-01 4.48e-05
mRNA Splicing 187 2.51e-06 -2.00e-01 4.96e-05
Mitotic Prometaphase 184 2.79e-06 -2.00e-01 5.44e-05
Interactions of Vpr with host cellular proteins 37 3.55e-06 -4.40e-01 6.81e-05
FCGR3A-mediated IL10 synthesis 99 3.84e-06 -2.69e-01 7.27e-05
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 182 4.09e-06 -1.98e-01 7.55e-05
Post-translational protein phosphorylation 70 4.10e-06 3.18e-01 7.55e-05
Interactions of Rev with host cellular proteins 37 4.77e-06 -4.35e-01 8.66e-05
S Phase 160 5.65e-06 -2.08e-01 1.01e-04
Mitochondrial translation elongation 91 6.17e-06 -2.74e-01 1.09e-04
IRAK4 deficiency (TLR2/4) 10 6.62e-06 8.23e-01 1.14e-04
MyD88 deficiency (TLR2/4) 10 6.62e-06 8.23e-01 1.14e-04
DNA Repair 289 6.78e-06 -1.54e-01 1.16e-04
Binding and Uptake of Ligands by Scavenger Receptors 92 8.56e-06 -2.68e-01 1.44e-04
Rev-mediated nuclear export of HIV RNA 35 1.17e-05 -4.28e-01 1.93e-04
Mitochondrial translation termination 91 1.17e-05 -2.66e-01 1.93e-04
Clathrin-mediated endocytosis 127 1.21e-05 2.25e-01 1.96e-04
EPH-Ephrin signaling 79 1.22e-05 2.85e-01 1.96e-04
Mitochondrial translation 97 1.26e-05 -2.57e-01 1.99e-04
Mitochondrial translation initiation 91 1.48e-05 -2.63e-01 2.31e-04
Vpr-mediated nuclear import of PICs 34 1.50e-05 -4.29e-01 2.32e-04
Antigen processing-Cross presentation 97 1.74e-05 2.52e-01 2.66e-04
Phosphorylation of CD3 and TCR zeta chains 27 1.96e-05 -4.75e-01 2.96e-04
RHO GTPases Activate WASPs and WAVEs 35 2.11e-05 4.15e-01 3.16e-04
trans-Golgi Network Vesicle Budding 69 2.39e-05 2.94e-01 3.53e-04
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 81 2.53e-05 2.71e-01 3.71e-04
FCERI mediated MAPK activation 90 2.82e-05 -2.55e-01 4.09e-04
Nuclear import of Rev protein 34 2.89e-05 -4.14e-01 4.14e-04
Detoxification of Reactive Oxygen Species 32 3.05e-05 4.26e-01 4.33e-04
COPI-mediated anterograde transport 78 3.17e-05 2.72e-01 4.45e-04
NS1 Mediated Effects on Host Pathways 40 3.22e-05 -3.80e-01 4.48e-04
Signaling by Receptor Tyrosine Kinases 414 3.90e-05 1.18e-01 5.36e-04
SUMOylation 165 5.95e-05 -1.81e-01 8.07e-04
Degradation of the extracellular matrix 78 5.98e-05 2.63e-01 8.07e-04
Resolution of AP sites via the multiple-nucleotide patch replacement pathway 24 6.05e-05 -4.73e-01 8.09e-04
NEP/NS2 Interacts with the Cellular Export Machinery 32 6.13e-05 -4.09e-01 8.11e-04
Cellular response to heat stress 93 6.51e-05 -2.40e-01 8.53e-04
Regulation of HSF1-mediated heat shock response 79 7.09e-05 -2.59e-01 9.10e-04
Transport of Mature mRNA derived from an Intron-Containing Transcript 72 7.14e-05 -2.71e-01 9.10e-04
Postmitotic nuclear pore complex (NPC) reformation 27 7.16e-05 -4.41e-01 9.10e-04
G1/S-Specific Transcription 29 7.21e-05 -4.26e-01 9.10e-04
Regulation of TP53 Activity 151 7.29e-05 -1.87e-01 9.11e-04
Transport to the Golgi and subsequent modification 155 7.38e-05 1.84e-01 9.15e-04
Platelet activation, signaling and aggregation 221 8.16e-05 1.54e-01 1.00e-03
Cell Cycle Checkpoints 259 8.41e-05 -1.42e-01 1.02e-03
Telomere Maintenance 80 9.00e-05 -2.53e-01 1.09e-03
SUMOylation of DNA damage response and repair proteins 77 9.89e-05 -2.57e-01 1.18e-03
Asparagine N-linked glycosylation 269 1.06e-04 1.37e-01 1.26e-03
Infectious disease 775 1.11e-04 -8.16e-02 1.30e-03
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism 12 1.31e-04 6.37e-01 1.52e-03
alpha-linolenic acid (ALA) metabolism 12 1.31e-04 6.37e-01 1.52e-03
Transport of Ribonucleoproteins into the Host Nucleus 32 1.46e-04 -3.88e-01 1.67e-03
Lagging Strand Synthesis 20 1.47e-04 -4.90e-01 1.67e-03
tRNA modification in the nucleus and cytosol 43 1.52e-04 -3.34e-01 1.71e-03
Export of Viral Ribonucleoproteins from Nucleus 33 1.53e-04 -3.81e-01 1.71e-03
G1/S Transition 130 1.54e-04 -1.92e-01 1.71e-03
Transport of the SLBP Dependant Mature mRNA 36 1.67e-04 -3.63e-01 1.83e-03
Resolution of Sister Chromatid Cohesion 104 1.80e-04 -2.13e-01 1.97e-03
Regulation of Complement cascade 95 1.82e-04 -2.22e-01 1.97e-03
EPHB-mediated forward signaling 32 1.83e-04 3.82e-01 1.97e-03
BBSome-mediated cargo-targeting to cilium 22 1.90e-04 -4.60e-01 2.02e-03
SUMO E3 ligases SUMOylate target proteins 159 1.91e-04 -1.71e-01 2.02e-03
PPARA activates gene expression 104 1.94e-04 2.11e-01 2.04e-03
Cilium Assembly 180 1.99e-04 -1.61e-01 2.06e-03
Transport of small molecules 557 1.99e-04 9.22e-02 2.06e-03
Toll-like Receptor Cascades 143 2.05e-04 1.80e-01 2.11e-03
Unwinding of DNA 12 2.11e-04 -6.18e-01 2.15e-03
Transport of Mature Transcript to Cytoplasm 81 2.22e-04 -2.37e-01 2.24e-03
PCNA-Dependent Long Patch Base Excision Repair 21 2.29e-04 -4.64e-01 2.29e-03
Complement cascade 99 2.37e-04 -2.14e-01 2.36e-03
Polymerase switching on the C-strand of the telomere 26 2.49e-04 -4.15e-01 2.45e-03
Transport of the SLBP independent Mature mRNA 35 2.50e-04 -3.58e-01 2.45e-03
SUMOylation of RNA binding proteins 47 2.56e-04 -3.08e-01 2.49e-03
FCERI mediated NF-kB activation 137 2.59e-04 -1.81e-01 2.50e-03
tRNA Aminoacylation 42 2.63e-04 -3.25e-01 2.53e-03
RNA Polymerase I Transcription Initiation 44 2.78e-04 -3.17e-01 2.63e-03
ISG15 antiviral mechanism 72 2.79e-04 -2.48e-01 2.63e-03
Diseases associated with the TLR signaling cascade 23 2.81e-04 4.37e-01 2.63e-03
Diseases of Immune System 23 2.81e-04 4.37e-01 2.63e-03
SUMOylation of chromatin organization proteins 57 2.89e-04 -2.78e-01 2.68e-03
Signaling by Interleukins 385 3.05e-04 1.07e-01 2.81e-03
Chemokine receptors bind chemokines 37 3.40e-04 -3.40e-01 3.11e-03
Regulation of TLR by endogenous ligand 11 3.45e-04 6.23e-01 3.13e-03
Costimulation by the CD28 family 74 3.57e-04 -2.40e-01 3.18e-03
Toll Like Receptor 4 (TLR4) Cascade 121 3.58e-04 1.88e-01 3.18e-03
RHO GTPases Activate ROCKs 18 3.59e-04 4.86e-01 3.18e-03
Recognition of DNA damage by PCNA-containing replication complex 30 3.61e-04 -3.76e-01 3.18e-03
Regulation of lipid metabolism by PPARalpha 106 3.61e-04 2.00e-01 3.18e-03
Nuclear Pore Complex (NPC) Disassembly 36 3.64e-04 -3.43e-01 3.18e-03
Antiviral mechanism by IFN-stimulated genes 80 3.74e-04 -2.30e-01 3.25e-03
G0 and Early G1 27 4.38e-04 -3.91e-01 3.78e-03
ROS and RNS production in phagocytes 31 4.58e-04 3.64e-01 3.92e-03
Rab regulation of trafficking 121 4.86e-04 1.84e-01 4.14e-03
Resolution of Abasic Sites (AP sites) 37 4.98e-04 -3.31e-01 4.21e-03
Cargo recognition for clathrin-mediated endocytosis 90 5.06e-04 2.12e-01 4.26e-03
RAB GEFs exchange GTP for GDP on RABs 88 6.40e-04 2.11e-01 5.35e-03
Mitotic Spindle Checkpoint 108 6.58e-04 -1.90e-01 5.47e-03
Collagen degradation 29 6.92e-04 3.64e-01 5.72e-03
Plasma lipoprotein assembly, remodeling, and clearance 53 7.36e-04 2.68e-01 6.04e-03
Deadenylation-dependent mRNA decay 53 7.55e-04 -2.67e-01 6.16e-03
RHO GTPases Activate NADPH Oxidases 21 8.13e-04 4.22e-01 6.60e-03
SUMOylation of SUMOylation proteins 35 8.23e-04 -3.27e-01 6.64e-03
COPI-independent Golgi-to-ER retrograde traffic 33 8.51e-04 3.35e-01 6.83e-03
EML4 and NUDC in mitotic spindle formation 95 8.64e-04 -1.98e-01 6.88e-03
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 91 8.84e-04 -2.02e-01 6.96e-03
Amplification of signal from the kinetochores 91 8.84e-04 -2.02e-01 6.96e-03
Processive synthesis on the lagging strand 15 9.07e-04 -4.95e-01 7.11e-03
Metabolism of proteins 1714 9.36e-04 -4.81e-02 7.29e-03
Interleukin-1 family signaling 124 9.64e-04 1.72e-01 7.46e-03
Synthesis of DNA 118 9.81e-04 -1.76e-01 7.56e-03
COPII-mediated vesicle transport 65 9.90e-04 2.36e-01 7.58e-03
Signal transduction by L1 20 1.01e-03 4.24e-01 7.72e-03
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 11 1.04e-03 5.71e-01 7.86e-03
SUMOylation of DNA replication proteins 46 1.05e-03 -2.79e-01 7.91e-03
Transport of Mature mRNAs Derived from Intronless Transcripts 43 1.11e-03 -2.87e-01 8.30e-03
Anti-inflammatory response favouring Leishmania parasite infection 169 1.13e-03 -1.45e-01 8.38e-03
Leishmania parasite growth and survival 169 1.13e-03 -1.45e-01 8.38e-03
Interleukin-1 signaling 97 1.15e-03 1.91e-01 8.47e-03
MyD88:MAL(TIRAP) cascade initiated on plasma membrane 92 1.17e-03 1.96e-01 8.47e-03
Toll Like Receptor 2 (TLR2) Cascade 92 1.17e-03 1.96e-01 8.47e-03
Toll Like Receptor TLR1:TLR2 Cascade 92 1.17e-03 1.96e-01 8.47e-03
Toll Like Receptor TLR6:TLR2 Cascade 92 1.17e-03 1.96e-01 8.47e-03
ER-Phagosome pathway 82 1.26e-03 2.06e-01 9.01e-03
GPVI-mediated activation cascade 31 1.28e-03 3.34e-01 9.13e-03
Mitochondrial protein import 64 1.29e-03 -2.33e-01 9.17e-03
Hyaluronan uptake and degradation 12 1.32e-03 5.35e-01 9.29e-03
Signaling by NOTCH 182 1.32e-03 1.38e-01 9.29e-03
Intraflagellar transport 39 1.35e-03 -2.97e-01 9.36e-03
Transferrin endocytosis and recycling 26 1.35e-03 3.63e-01 9.36e-03
Telomere C-strand synthesis initiation 13 1.36e-03 -5.13e-01 9.36e-03
Transcriptional Regulation by E2F6 34 1.36e-03 -3.17e-01 9.36e-03
Signaling by the B Cell Receptor (BCR) 162 1.38e-03 -1.46e-01 9.43e-03
Nucleobase biosynthesis 13 1.45e-03 -5.10e-01 9.89e-03
Lysosome Vesicle Biogenesis 32 1.50e-03 3.24e-01 1.02e-02
Transcription of E2F targets under negative control by DREAM complex 19 1.51e-03 -4.20e-01 1.02e-02
DNA Replication 125 1.51e-03 -1.64e-01 1.02e-02
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 32 1.56e-03 -3.23e-01 1.04e-02
Regulation of Glucokinase by Glucokinase Regulatory Protein 32 1.56e-03 -3.23e-01 1.04e-02
Transport of Mature mRNA Derived from an Intronless Transcript 42 1.59e-03 -2.82e-01 1.05e-02
Golgi Associated Vesicle Biogenesis 55 1.61e-03 2.46e-01 1.06e-02
Nuclear Envelope Breakdown 53 1.69e-03 -2.49e-01 1.11e-02
VLDLR internalisation and degradation 12 1.78e-03 5.21e-01 1.16e-02
Mitotic G1 phase and G1/S transition 148 1.80e-03 -1.49e-01 1.17e-02
Organelle biogenesis and maintenance 268 1.90e-03 -1.10e-01 1.23e-02
Golgi-to-ER retrograde transport 111 2.10e-03 1.69e-01 1.35e-02
RHO GTPases activate PKNs 48 2.14e-03 2.56e-01 1.37e-02
Homologous DNA Pairing and Strand Exchange 42 2.17e-03 -2.73e-01 1.38e-02
DNA Damage Bypass 47 2.22e-03 -2.58e-01 1.41e-02
Removal of the Flap Intermediate 14 2.48e-03 -4.67e-01 1.57e-02
Translesion synthesis by REV1 16 2.58e-03 -4.35e-01 1.61e-02
Cell surface interactions at the vascular wall 174 2.60e-03 -1.32e-01 1.61e-02
Neuronal System 258 2.60e-03 1.09e-01 1.61e-02
Insulin receptor recycling 21 2.60e-03 3.80e-01 1.61e-02
Cellular responses to stress 499 2.61e-03 -7.87e-02 1.61e-02
Dual Incision in GG-NER 41 2.71e-03 -2.71e-01 1.67e-02
Processive synthesis on the C-strand of the telomere 19 2.78e-03 -3.96e-01 1.70e-02
NOTCH4 Activation and Transmission of Signal to the Nucleus 10 2.84e-03 5.45e-01 1.73e-02
Termination of translesion DNA synthesis 32 2.87e-03 -3.05e-01 1.74e-02
Signal Transduction 1882 3.05e-03 4.13e-02 1.84e-02
Synthesis of Leukotrienes (LT) and Eoxins (EX) 15 3.06e-03 4.42e-01 1.84e-02
Mitochondrial tRNA aminoacylation 21 3.09e-03 -3.73e-01 1.84e-02
Gene Silencing by RNA 87 3.09e-03 -1.84e-01 1.84e-02
Cellular response to hypoxia 71 3.15e-03 2.03e-01 1.87e-02
DNA Double-Strand Break Repair 135 3.38e-03 -1.46e-01 1.99e-02
L1CAM interactions 85 3.48e-03 1.83e-01 2.04e-02
Viral Messenger RNA Synthesis 44 3.57e-03 -2.54e-01 2.09e-02
Heme degradation 10 3.64e-03 5.31e-01 2.12e-02
MAP2K and MAPK activation 34 3.74e-03 2.87e-01 2.17e-02
Pre-NOTCH Processing in Golgi 18 3.81e-03 3.94e-01 2.20e-02
Early Phase of HIV Life Cycle 14 3.92e-03 -4.45e-01 2.25e-02
Gap-filling DNA repair synthesis and ligation in GG-NER 25 3.92e-03 -3.33e-01 2.25e-02
Intra-Golgi and retrograde Golgi-to-ER traffic 179 3.95e-03 1.25e-01 2.25e-02
Presynaptic phase of homologous DNA pairing and strand exchange 39 4.07e-03 -2.66e-01 2.31e-02
Signaling by NOTCH4 78 4.14e-03 1.88e-01 2.34e-02
Platelet sensitization by LDL 16 4.20e-03 4.13e-01 2.36e-02
Translesion synthesis by POLI 17 4.41e-03 -3.99e-01 2.48e-02
HDR through Homologous Recombination (HRR) 66 4.48e-03 -2.02e-01 2.50e-02
Cellular responses to external stimuli 505 4.74e-03 -7.34e-02 2.64e-02
Base Excision Repair 58 4.84e-03 -2.14e-01 2.68e-02
Semaphorin interactions 57 4.86e-03 2.16e-01 2.68e-02
Gap junction trafficking 13 4.93e-03 4.50e-01 2.71e-02
Fc epsilon receptor (FCERI) signaling 190 5.23e-03 -1.17e-01 2.86e-02
MET activates RAP1 and RAC1 10 5.25e-03 5.10e-01 2.86e-02
Nucleotide Excision Repair 110 5.66e-03 -1.53e-01 3.07e-02
Ion channel transport 133 5.68e-03 1.39e-01 3.07e-02
Programmed Cell Death 178 5.82e-03 1.20e-01 3.14e-02
M Phase 359 5.87e-03 -8.46e-02 3.15e-02
Sema4D in semaphorin signaling 22 5.95e-03 3.39e-01 3.17e-02
HCMV Early Events 74 5.95e-03 -1.85e-01 3.17e-02
Signaling by Erythropoietin 24 6.10e-03 3.23e-01 3.24e-02
Transcription-Coupled Nucleotide Excision Repair (TC-NER) 78 6.34e-03 -1.79e-01 3.35e-02
E2F mediated regulation of DNA replication 22 6.37e-03 -3.36e-01 3.35e-02
Signaling by NTRKs 116 6.47e-03 1.46e-01 3.39e-02
Transcriptional Regulation by TP53 351 6.51e-03 -8.45e-02 3.40e-02
Hyaluronan metabolism 15 6.74e-03 4.04e-01 3.51e-02
Advanced glycosylation endproduct receptor signaling 12 6.76e-03 4.51e-01 3.51e-02
Signaling by Rho GTPases 367 7.03e-03 8.19e-02 3.63e-02
Translesion synthesis by POLK 17 7.28e-03 -3.76e-01 3.75e-02
Rho GTPase cycle 126 7.63e-03 1.38e-01 3.90e-02
Fanconi Anemia Pathway 36 7.64e-03 -2.57e-01 3.90e-02
Endosomal Sorting Complex Required For Transport (ESCRT) 29 7.90e-03 2.85e-01 4.02e-02
Toll Like Receptor 7/8 (TLR7/8) Cascade 89 7.99e-03 1.63e-01 4.05e-02
Gluconeogenesis 28 8.23e-03 2.88e-01 4.16e-02
Cargo concentration in the ER 30 8.37e-03 2.78e-01 4.21e-02
Dual incision in TC-NER 65 8.43e-03 -1.89e-01 4.22e-02
Recycling pathway of L1 26 8.55e-03 2.98e-01 4.27e-02
WNT5A-dependent internalization of FZD4 13 8.74e-03 4.20e-01 4.34e-02
Gap-filling DNA repair synthesis and ligation in TC-NER 64 8.75e-03 -1.89e-01 4.34e-02
Regulation of TP53 Activity through Phosphorylation 88 8.97e-03 -1.61e-01 4.43e-02
Notch-HLH transcription pathway 28 9.05e-03 2.85e-01 4.45e-02
Cross-presentation of soluble exogenous antigens (endosomes) 47 9.26e-03 2.19e-01 4.53e-02
VEGFA-VEGFR2 Pathway 92 9.27e-03 1.57e-01 4.53e-02
Global Genome Nucleotide Excision Repair (GG-NER) 84 9.36e-03 -1.64e-01 4.56e-02
PCP/CE pathway 86 9.42e-03 1.62e-01 4.57e-02
G-protein beta:gamma signalling 29 9.51e-03 2.78e-01 4.60e-02
Dectin-2 family 19 9.69e-03 3.43e-01 4.64e-02
SUMOylation of ubiquitinylation proteins 39 9.70e-03 -2.39e-01 4.64e-02
Dissolution of Fibrin Clot 12 9.70e-03 4.31e-01 4.64e-02
Response to elevated platelet cytosolic Ca2+ 110 9.74e-03 1.43e-01 4.64e-02
Removal of the Flap Intermediate from the C-strand 17 9.82e-03 -3.62e-01 4.67e-02
Pre-NOTCH Expression and Processing 65 9.90e-03 1.85e-01 4.68e-02
Regulation of TP53 Activity through Acetylation 29 1.00e-02 -2.76e-01 4.72e-02
Signaling by high-kinase activity BRAF mutants 31 1.01e-02 2.67e-01 4.74e-02
Homology Directed Repair 110 1.01e-02 -1.42e-01 4.74e-02
RNA Polymerase II Transcription Termination 65 1.03e-02 -1.84e-01 4.83e-02
Diseases of signal transduction by growth factor receptors and second messengers 339 1.05e-02 8.09e-02 4.87e-02
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 11 1.07e-02 -4.45e-01 4.95e-02
Integration of energy metabolism 86 1.07e-02 1.59e-01 4.96e-02
Telomere Extension By Telomerase 23 1.10e-02 -3.06e-01 5.05e-02
Establishment of Sister Chromatid Cohesion 11 1.10e-02 -4.43e-01 5.06e-02
Metabolism of carbohydrates 244 1.13e-02 9.42e-02 5.15e-02
RNA Polymerase III Transcription Initiation From Type 1 Promoter 28 1.15e-02 -2.76e-01 5.25e-02
mRNA decay by 3’ to 5’ exoribonuclease 16 1.16e-02 -3.65e-01 5.26e-02
Gap junction trafficking and regulation 15 1.19e-02 3.75e-01 5.38e-02
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 16 1.19e-02 -3.63e-01 5.38e-02
Translesion Synthesis by POLH 18 1.20e-02 -3.42e-01 5.38e-02
Regulation of PLK1 Activity at G2/M Transition 86 1.21e-02 -1.57e-01 5.41e-02
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 64 1.21e-02 1.81e-01 5.43e-02
Extracellular matrix organization 219 1.22e-02 9.82e-02 5.45e-02
MyD88 dependent cascade initiated on endosome 88 1.25e-02 1.54e-01 5.53e-02
Leading Strand Synthesis 14 1.26e-02 -3.85e-01 5.58e-02
Polymerase switching 14 1.26e-02 -3.85e-01 5.58e-02
HATs acetylate histones 93 1.29e-02 -1.49e-01 5.67e-02
Epigenetic regulation of gene expression 100 1.29e-02 -1.44e-01 5.67e-02
Potassium Channels 63 1.31e-02 1.81e-01 5.73e-02
Olfactory Signaling Pathway 58 1.33e-02 1.88e-01 5.80e-02
Interleukin-3, Interleukin-5 and GM-CSF signaling 40 1.35e-02 2.26e-01 5.87e-02
Purine ribonucleoside monophosphate biosynthesis 10 1.39e-02 -4.49e-01 5.99e-02
Mismatch Repair 15 1.39e-02 -3.67e-01 5.99e-02
Budding and maturation of HIV virion 26 1.40e-02 2.78e-01 6.02e-02
LDL clearance 18 1.41e-02 3.34e-01 6.02e-02
Growth hormone receptor signaling 20 1.44e-02 3.16e-01 6.14e-02
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 13 1.50e-02 3.90e-01 6.35e-02
Platelet degranulation 106 1.50e-02 1.37e-01 6.35e-02
Sema4D induced cell migration and growth-cone collapse 19 1.51e-02 3.22e-01 6.40e-02
Recruitment of NuMA to mitotic centrosomes 79 1.59e-02 -1.57e-01 6.73e-02
Regulation of FZD by ubiquitination 15 1.62e-02 -3.59e-01 6.81e-02
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 14 1.62e-02 -3.71e-01 6.81e-02
Signaling by MET 61 1.64e-02 1.78e-01 6.87e-02
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 38 1.65e-02 -2.25e-01 6.88e-02
Glycosphingolipid metabolism 36 1.66e-02 2.31e-01 6.88e-02
Apoptosis 166 1.67e-02 1.08e-01 6.91e-02
SLBP independent Processing of Histone Pre-mRNAs 10 1.70e-02 -4.36e-01 7.04e-02
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 11 1.72e-02 4.15e-01 7.07e-02
Regulation of PTEN stability and activity 66 1.72e-02 1.70e-01 7.07e-02
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 87 1.73e-02 1.48e-01 7.07e-02
HDR through Single Strand Annealing (SSA) 37 1.74e-02 -2.26e-01 7.07e-02
Signaling by RAF1 mutants 34 1.74e-02 2.36e-01 7.07e-02
Phospholipid metabolism 186 1.74e-02 1.01e-01 7.07e-02
Sphingolipid metabolism 78 1.76e-02 1.56e-01 7.10e-02
Erythropoietin activates RAS 13 1.76e-02 3.80e-01 7.10e-02
PINK1-PRKN Mediated Mitophagy 21 1.79e-02 -2.98e-01 7.19e-02
Regulation of TP53 Expression and Degradation 36 1.81e-02 -2.28e-01 7.26e-02
HIV Life Cycle 144 1.85e-02 -1.14e-01 7.41e-02
TNFs bind their physiological receptors 25 1.88e-02 -2.71e-01 7.50e-02
Hedgehog ligand biogenesis 58 1.89e-02 1.78e-01 7.52e-02
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20 1.90e-02 -3.03e-01 7.52e-02
Activation of Matrix Metalloproteinases 23 1.90e-02 2.82e-01 7.52e-02
Uptake and function of anthrax toxins 10 1.92e-02 4.28e-01 7.56e-02
Muscle contraction 135 1.93e-02 1.17e-01 7.59e-02
Positive epigenetic regulation of rRNA expression 59 1.95e-02 -1.76e-01 7.63e-02
Processing of DNA double-strand break ends 71 1.98e-02 -1.60e-01 7.73e-02
Cytosolic tRNA aminoacylation 24 2.01e-02 -2.74e-01 7.81e-02
TBC/RABGAPs 45 2.01e-02 2.00e-01 7.81e-02
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 14 2.12e-02 -3.56e-01 8.19e-02
mRNA Splicing - Minor Pathway 52 2.16e-02 -1.84e-01 8.34e-02
RNA Polymerase III Transcription Initiation From Type 2 Promoter 27 2.21e-02 -2.54e-01 8.51e-02
Signaling by VEGF 100 2.22e-02 1.32e-01 8.51e-02
Plasma lipoprotein clearance 29 2.23e-02 2.45e-01 8.51e-02
Signaling by NTRK1 (TRKA) 101 2.23e-02 1.32e-01 8.51e-02
Centrosome maturation 80 2.29e-02 -1.47e-01 8.71e-02
Recruitment of mitotic centrosome proteins and complexes 80 2.29e-02 -1.47e-01 8.71e-02
Metabolism of steroids 119 2.30e-02 1.21e-01 8.72e-02
EPH-ephrin mediated repulsion of cells 40 2.32e-02 2.07e-01 8.77e-02
RHO GTPases activate CIT 18 2.35e-02 3.08e-01 8.86e-02
GABA receptor activation 35 2.36e-02 2.21e-01 8.87e-02
Collagen formation 66 2.41e-02 1.61e-01 9.02e-02
Anchoring of the basal body to the plasma membrane 96 2.46e-02 -1.33e-01 9.18e-02
Negative regulation of MET activity 18 2.51e-02 3.05e-01 9.36e-02
Retrograde neurotrophin signalling 12 2.53e-02 3.73e-01 9.40e-02
Deposition of new CENPA-containing nucleosomes at the centromere 40 2.57e-02 -2.04e-01 9.48e-02
Nucleosome assembly 40 2.57e-02 -2.04e-01 9.48e-02
Mitotic Metaphase and Anaphase 224 2.57e-02 -8.65e-02 9.48e-02
Transmission across Chemical Synapses 172 2.61e-02 9.83e-02 9.60e-02
TP53 Regulates Transcription of Cell Cycle Genes 48 2.64e-02 -1.85e-01 9.67e-02
Separation of Sister Chromatids 167 2.74e-02 -9.90e-02 9.97e-02
Amino acids regulate mTORC1 50 2.74e-02 1.80e-01 9.97e-02
Transcriptional regulation of white adipocyte differentiation 77 2.79e-02 1.45e-01 1.02e-01
Caspase activation via extrinsic apoptotic signalling pathway 25 2.81e-02 2.54e-01 1.02e-01
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 17 2.85e-02 -3.07e-01 1.03e-01
Oncogenic MAPK signaling 73 2.86e-02 1.48e-01 1.03e-01
RNA Polymerase I Transcription Termination 27 2.88e-02 -2.43e-01 1.04e-01
Transport of bile salts and organic acids, metal ions and amine compounds 55 2.91e-02 1.70e-01 1.04e-01
RAB geranylgeranylation 60 2.91e-02 1.63e-01 1.04e-01
Hh mutants that don’t undergo autocatalytic processing are degraded by ERAD 53 2.91e-02 1.73e-01 1.04e-01
MyD88-independent TLR4 cascade 96 2.93e-02 1.29e-01 1.04e-01
TRIF(TICAM1)-mediated TLR4 signaling 96 2.93e-02 1.29e-01 1.04e-01
G2/M Checkpoints 139 2.98e-02 -1.07e-01 1.05e-01
G2/M DNA damage checkpoint 68 3.00e-02 -1.52e-01 1.06e-01
Defects in vitamin and cofactor metabolism 21 3.04e-02 -2.73e-01 1.07e-01
Regulation of TP53 Degradation 35 3.04e-02 -2.11e-01 1.07e-01
Toll Like Receptor 9 (TLR9) Cascade 92 3.09e-02 1.30e-01 1.08e-01
CD28 dependent PI3K/Akt signaling 22 3.23e-02 -2.64e-01 1.13e-01
Defective CFTR causes cystic fibrosis 59 3.24e-02 1.61e-01 1.13e-01
rRNA processing in the mitochondrion 27 3.33e-02 -2.37e-01 1.16e-01
Mitotic Anaphase 223 3.35e-02 -8.26e-02 1.16e-01
RNA Polymerase III Chain Elongation 18 3.37e-02 -2.89e-01 1.17e-01
Integrin signaling 22 3.38e-02 2.61e-01 1.17e-01
Mucopolysaccharidoses 11 3.41e-02 3.69e-01 1.17e-01
RHO GTPases Activate Formins 117 3.43e-02 -1.13e-01 1.18e-01
Metabolism 1768 3.45e-02 3.03e-02 1.18e-01
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 104 3.47e-02 -1.20e-01 1.19e-01
Energy dependent regulation of mTOR by LKB1-AMPK 27 3.53e-02 2.34e-01 1.20e-01
Folding of actin by CCT/TriC 10 3.57e-02 -3.83e-01 1.22e-01
Regulation of IFNG signaling 14 3.59e-02 3.24e-01 1.22e-01
Pentose phosphate pathway 13 3.65e-02 3.35e-01 1.23e-01
Late endosomal microautophagy 30 3.65e-02 2.21e-01 1.23e-01
MHC class II antigen presentation 101 3.72e-02 1.20e-01 1.25e-01
RHO GTPases activate IQGAPs 11 3.73e-02 3.63e-01 1.25e-01
G2/M Transition 179 3.77e-02 -9.01e-02 1.26e-01
Iron uptake and transport 52 3.78e-02 1.67e-01 1.26e-01
Paradoxical activation of RAF signaling by kinase inactive BRAF 38 3.84e-02 1.94e-01 1.27e-01
Signaling by RAS mutants 38 3.84e-02 1.94e-01 1.27e-01
Signaling by moderate kinase activity BRAF mutants 38 3.84e-02 1.94e-01 1.27e-01
Signaling downstream of RAS mutants 38 3.84e-02 1.94e-01 1.27e-01
Intra-Golgi traffic 43 3.87e-02 1.82e-01 1.28e-01
Long-term potentiation 14 3.91e-02 -3.18e-01 1.29e-01
RNA Polymerase III Transcription Initiation 36 4.14e-02 -1.96e-01 1.36e-01
Host Interactions of HIV factors 129 4.15e-02 -1.04e-01 1.36e-01
Regulation of ornithine decarboxylase (ODC) 49 4.16e-02 1.68e-01 1.36e-01
Signaling by BRAF and RAF fusions 57 4.25e-02 1.55e-01 1.39e-01
VxPx cargo-targeting to cilium 19 4.27e-02 2.69e-01 1.39e-01
Diseases of DNA repair 10 4.27e-02 -3.70e-01 1.39e-01
HDR through MMEJ (alt-NHEJ) 10 4.30e-02 -3.70e-01 1.39e-01
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 33 4.31e-02 2.03e-01 1.39e-01
RHO GTPase Effectors 250 4.32e-02 7.43e-02 1.39e-01
APC-Cdc20 mediated degradation of Nek2A 26 4.32e-02 -2.29e-01 1.39e-01
Golgi Cisternae Pericentriolar Stack Reorganization 14 4.43e-02 3.10e-01 1.42e-01
Mitotic G2-G2/M phases 181 4.44e-02 -8.66e-02 1.42e-01
Hh mutants abrogate ligand secretion 54 4.49e-02 1.58e-01 1.43e-01
Glycosaminoglycan metabolism 94 4.51e-02 1.20e-01 1.44e-01
Metabolism of steroid hormones 20 4.53e-02 2.59e-01 1.44e-01
RNA Polymerase I Promoter Clearance 63 4.65e-02 -1.45e-01 1.47e-01
RNA Polymerase I Transcription 63 4.65e-02 -1.45e-01 1.47e-01
Pre-NOTCH Transcription and Translation 49 4.66e-02 1.64e-01 1.47e-01
RHO GTPases activate PAKs 20 4.66e-02 2.57e-01 1.47e-01
Plasma lipoprotein remodeling 18 4.68e-02 2.71e-01 1.47e-01
Downstream TCR signaling 100 4.69e-02 -1.15e-01 1.47e-01
Activated NOTCH1 Transmits Signal to the Nucleus 27 4.74e-02 2.20e-01 1.48e-01
Regulated proteolysis of p75NTR 11 4.82e-02 3.44e-01 1.50e-01
Effects of PIP2 hydrolysis 24 4.98e-02 -2.31e-01 1.55e-01
ABC transporter disorders 70 4.99e-02 1.36e-01 1.55e-01
Beta-catenin independent WNT signaling 136 5.01e-02 9.73e-02 1.55e-01
Activation of GABAB receptors 30 5.03e-02 2.06e-01 1.55e-01
GABA B receptor activation 30 5.03e-02 2.06e-01 1.55e-01
MTOR signalling 39 5.03e-02 1.81e-01 1.55e-01
Signaling by NOTCH1 66 5.11e-02 1.39e-01 1.57e-01
AURKA Activation by TPX2 71 5.11e-02 -1.34e-01 1.57e-01
Glycerophospholipid biosynthesis 107 5.15e-02 1.09e-01 1.57e-01
Diseases of carbohydrate metabolism 29 5.18e-02 2.09e-01 1.58e-01
DNA Replication Pre-Initiation 82 5.27e-02 -1.24e-01 1.60e-01
MyD88 cascade initiated on plasma membrane 82 5.43e-02 1.23e-01 1.64e-01
Toll Like Receptor 10 (TLR10) Cascade 82 5.43e-02 1.23e-01 1.64e-01
Toll Like Receptor 5 (TLR5) Cascade 82 5.43e-02 1.23e-01 1.64e-01
Regulation of signaling by CBL 18 5.47e-02 2.62e-01 1.65e-01
Degradation of DVL 54 5.48e-02 1.51e-01 1.65e-01
Neurotransmitter receptors and postsynaptic signal transmission 123 5.51e-02 1.00e-01 1.65e-01
RNA Polymerase III Abortive And Retractive Initiation 41 5.53e-02 -1.73e-01 1.65e-01
RNA Polymerase III Transcription 41 5.53e-02 -1.73e-01 1.65e-01
activated TAK1 mediates p38 MAPK activation 19 5.54e-02 2.54e-01 1.65e-01
Glutamate and glutamine metabolism 12 5.61e-02 -3.18e-01 1.67e-01
Synthesis of PC 24 5.64e-02 2.25e-01 1.67e-01
Chondroitin sulfate biosynthesis 12 5.78e-02 3.16e-01 1.71e-01
Myogenesis 21 5.81e-02 2.39e-01 1.72e-01
AKT phosphorylates targets in the cytosol 14 5.85e-02 2.92e-01 1.73e-01
Tight junction interactions 18 5.88e-02 -2.57e-01 1.73e-01
C-type lectin receptors (CLRs) 128 5.88e-02 9.67e-02 1.73e-01
Regulation of activated PAK-2p34 by proteasome mediated degradation 48 5.90e-02 1.58e-01 1.73e-01
Loss of Nlp from mitotic centrosomes 68 5.94e-02 -1.32e-01 1.73e-01
Loss of proteins required for interphase microtubule organization from the centrosome 68 5.94e-02 -1.32e-01 1.73e-01
RNA Polymerase III Transcription Termination 23 5.94e-02 -2.27e-01 1.73e-01
Signaling by GPCR 536 5.98e-02 4.75e-02 1.74e-01
Glutathione conjugation 26 6.02e-02 2.13e-01 1.74e-01
Vif-mediated degradation of APOBEC3G 52 6.03e-02 1.51e-01 1.74e-01
Signaling by Insulin receptor 59 6.04e-02 1.41e-01 1.74e-01
The NLRP3 inflammasome 15 6.05e-02 2.80e-01 1.74e-01
Translocation of SLC2A4 (GLUT4) to the plasma membrane 48 6.08e-02 1.56e-01 1.74e-01
Signalling to ERKs 32 6.08e-02 1.91e-01 1.74e-01
Fatty acid metabolism 152 6.13e-02 8.79e-02 1.76e-01
Signaling by SCF-KIT 40 6.15e-02 1.71e-01 1.76e-01
mRNA 3’-end processing 56 6.16e-02 -1.44e-01 1.76e-01
Prolonged ERK activation events 13 6.27e-02 2.98e-01 1.79e-01
Metabolism of porphyrins 22 6.35e-02 2.29e-01 1.80e-01
Stimuli-sensing channels 73 6.41e-02 1.25e-01 1.82e-01
Sealing of the nuclear envelope (NE) by ESCRT-III 25 6.47e-02 2.13e-01 1.83e-01
Mitophagy 28 6.47e-02 -2.02e-01 1.83e-01
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 11 6.60e-02 3.20e-01 1.86e-01
Inactivation of APC/C via direct inhibition of the APC/C complex 21 6.76e-02 -2.30e-01 1.90e-01
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 21 6.76e-02 -2.30e-01 1.90e-01
Regulation of cholesterol biosynthesis by SREBP (SREBF) 55 6.78e-02 1.42e-01 1.90e-01
Negative regulation of NOTCH4 signaling 54 6.79e-02 1.44e-01 1.90e-01
RAS processing 19 6.84e-02 -2.41e-01 1.90e-01
Smooth Muscle Contraction 31 6.84e-02 1.89e-01 1.90e-01
Platelet homeostasis 68 6.86e-02 1.28e-01 1.90e-01
HDMs demethylate histones 22 6.88e-02 2.24e-01 1.90e-01
Autophagy 124 6.88e-02 9.46e-02 1.90e-01
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 31 7.05e-02 -1.88e-01 1.95e-01
Degradation of GLI1 by the proteasome 57 7.11e-02 1.38e-01 1.96e-01
Transcriptional regulation by small RNAs 63 7.24e-02 -1.31e-01 1.99e-01
Formation of the cornified envelope 21 7.29e-02 2.26e-01 2.00e-01
Interferon Signaling 177 7.37e-02 -7.79e-02 2.02e-01
Regulation of IFNA signaling 12 7.55e-02 2.96e-01 2.06e-01
RUNX1 regulates transcription of genes involved in differentiation of HSCs 82 7.62e-02 1.13e-01 2.08e-01
ERKs are inactivated 13 7.64e-02 2.84e-01 2.08e-01
Transcriptional regulation by RUNX2 101 7.72e-02 1.02e-01 2.10e-01
XBP1(S) activates chaperone genes 47 7.76e-02 1.49e-01 2.10e-01
Axon guidance 455 7.79e-02 -4.82e-02 2.11e-01
Formation of Incision Complex in GG-NER 43 7.88e-02 -1.55e-01 2.13e-01
ADP signalling through P2Y purinoceptor 1 21 7.90e-02 2.21e-01 2.13e-01
Scavenging by Class A Receptors 11 8.08e-02 3.04e-01 2.17e-01
Metabolism of amine-derived hormones 10 8.09e-02 -3.19e-01 2.17e-01
RNA Polymerase III Transcription Initiation From Type 3 Promoter 28 8.16e-02 -1.90e-01 2.19e-01
Assembly of collagen fibrils and other multimeric structures 42 8.24e-02 1.55e-01 2.20e-01
Hedgehog ‘on’ state 75 8.41e-02 1.15e-01 2.24e-01
Signal regulatory protein family interactions 12 8.43e-02 2.88e-01 2.24e-01
Regulation of Apoptosis 51 8.63e-02 1.39e-01 2.29e-01
Nephrin family interactions 17 8.83e-02 -2.39e-01 2.34e-01
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer’s disease models 21 8.84e-02 2.15e-01 2.34e-01
Neurodegenerative Diseases 21 8.84e-02 2.15e-01 2.34e-01
Nervous system development 474 8.86e-02 -4.57e-02 2.34e-01
Hemostasis 547 8.96e-02 4.24e-02 2.36e-01
PERK regulates gene expression 30 9.04e-02 -1.79e-01 2.38e-01
Deadenylation of mRNA 22 9.08e-02 -2.08e-01 2.38e-01
G alpha (s) signalling events 141 9.21e-02 8.22e-02 2.41e-01
CLEC7A (Dectin-1) induces NFAT activation 11 9.23e-02 -2.93e-01 2.41e-01
Processing of Capped Intronless Pre-mRNA 28 9.25e-02 -1.84e-01 2.41e-01
Endogenous sterols 17 9.45e-02 2.34e-01 2.46e-01
mRNA decay by 5’ to 3’ exoribonuclease 15 9.46e-02 -2.49e-01 2.46e-01
Signal amplification 28 9.51e-02 1.82e-01 2.46e-01
Interconversion of nucleotide di- and triphosphates 27 9.57e-02 -1.85e-01 2.47e-01
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 17 9.57e-02 -2.33e-01 2.47e-01
HSF1 activation 26 9.59e-02 -1.89e-01 2.47e-01
TCR signaling 121 9.61e-02 -8.76e-02 2.47e-01
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 51 9.71e-02 1.34e-01 2.49e-01
Defects in cobalamin (B12) metabolism 13 9.77e-02 -2.65e-01 2.50e-01
Trafficking of GluR2-containing AMPA receptors 12 1.01e-01 2.74e-01 2.57e-01
SUMOylation of immune response proteins 11 1.03e-01 2.84e-01 2.63e-01
Biotin transport and metabolism 11 1.03e-01 -2.84e-01 2.63e-01
MET promotes cell motility 26 1.04e-01 1.84e-01 2.64e-01
Response of Mtb to phagocytosis 22 1.04e-01 2.00e-01 2.64e-01
A tetrasaccharide linker sequence is required for GAG synthesis 17 1.06e-01 -2.27e-01 2.67e-01
NCAM1 interactions 23 1.06e-01 -1.95e-01 2.67e-01
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 27 1.06e-01 -1.80e-01 2.67e-01
IRE1alpha activates chaperones 49 1.07e-01 1.33e-01 2.68e-01
PIWI-interacting RNA (piRNA) biogenesis 23 1.07e-01 -1.94e-01 2.69e-01
Glycogen breakdown (glycogenolysis) 13 1.08e-01 2.57e-01 2.70e-01
RAF activation 32 1.08e-01 1.64e-01 2.70e-01
Plasma lipoprotein assembly 10 1.08e-01 2.93e-01 2.70e-01
Inflammasomes 20 1.08e-01 2.07e-01 2.70e-01
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 52 1.10e-01 1.28e-01 2.73e-01
Late Phase of HIV Life Cycle 131 1.10e-01 -8.09e-02 2.73e-01
G beta:gamma signalling through PI3Kgamma 22 1.10e-01 1.97e-01 2.73e-01
RHO GTPases activate KTN1 11 1.13e-01 2.76e-01 2.80e-01
Opioid Signalling 75 1.14e-01 1.06e-01 2.81e-01
Thrombin signalling through proteinase activated receptors (PARs) 27 1.16e-01 1.75e-01 2.85e-01
Regulation of insulin secretion 60 1.16e-01 1.17e-01 2.85e-01
SLC-mediated transmembrane transport 180 1.16e-01 6.79e-02 2.86e-01
Formation of TC-NER Pre-Incision Complex 53 1.17e-01 -1.25e-01 2.86e-01
Retinoid metabolism and transport 24 1.17e-01 1.85e-01 2.87e-01
PTEN Regulation 138 1.18e-01 7.71e-02 2.88e-01
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 17 1.19e-01 -2.19e-01 2.90e-01
AUF1 (hnRNP D0) binds and destabilizes mRNA 53 1.20e-01 1.23e-01 2.93e-01
Mitochondrial calcium ion transport 22 1.21e-01 -1.91e-01 2.94e-01
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 17 1.21e-01 2.17e-01 2.95e-01
Beta-oxidation of very long chain fatty acids 10 1.22e-01 2.82e-01 2.96e-01
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 50 1.23e-01 1.26e-01 2.96e-01
p53-Independent DNA Damage Response 50 1.23e-01 1.26e-01 2.96e-01
p53-Independent G1/S DNA damage checkpoint 50 1.23e-01 1.26e-01 2.96e-01
APC/C:Cdc20 mediated degradation of Cyclin B 24 1.23e-01 -1.82e-01 2.97e-01
NR1H2 and NR1H3-mediated signaling 39 1.26e-01 1.42e-01 3.02e-01
Adaptive Immune System 756 1.27e-01 -3.26e-02 3.04e-01
Degradation of GLI2 by the proteasome 56 1.31e-01 1.17e-01 3.13e-01
Meiosis 68 1.31e-01 -1.06e-01 3.14e-01
Cobalamin (Cbl, vitamin B12) transport and metabolism 16 1.32e-01 -2.18e-01 3.15e-01
KSRP (KHSRP) binds and destabilizes mRNA 17 1.32e-01 -2.11e-01 3.15e-01
NCAM signaling for neurite out-growth 43 1.32e-01 -1.33e-01 3.15e-01
Cohesin Loading onto Chromatin 10 1.33e-01 -2.74e-01 3.17e-01
Interleukin-15 signaling 14 1.34e-01 2.31e-01 3.17e-01
SLC transporter disorders 77 1.34e-01 -9.88e-02 3.17e-01
p75 NTR receptor-mediated signalling 89 1.34e-01 9.18e-02 3.17e-01
COPI-dependent Golgi-to-ER retrograde traffic 78 1.35e-01 9.78e-02 3.19e-01
Signaling by WNT 253 1.35e-01 5.45e-02 3.19e-01
Infection with Mycobacterium tuberculosis 26 1.36e-01 1.69e-01 3.21e-01
Toll Like Receptor 3 (TLR3) Cascade 92 1.37e-01 8.98e-02 3.21e-01
Protein localization 157 1.38e-01 -6.86e-02 3.24e-01
Cell recruitment (pro-inflammatory response) 22 1.41e-01 1.81e-01 3.29e-01
Purinergic signaling in leishmaniasis infection 22 1.41e-01 1.81e-01 3.29e-01
Regulation of RAS by GAPs 66 1.42e-01 1.05e-01 3.30e-01
Signaling by Leptin 10 1.42e-01 2.68e-01 3.30e-01
B-WICH complex positively regulates rRNA expression 44 1.43e-01 -1.28e-01 3.31e-01
Class I MHC mediated antigen processing & presentation 349 1.43e-01 4.56e-02 3.31e-01
TP53 Regulates Metabolic Genes 84 1.44e-01 9.23e-02 3.31e-01
Carboxyterminal post-translational modifications of tubulin 26 1.44e-01 1.66e-01 3.31e-01
NIK–>noncanonical NF-kB signaling 57 1.44e-01 1.12e-01 3.31e-01
Transcriptional regulation by RUNX3 90 1.44e-01 8.91e-02 3.31e-01
Spry regulation of FGF signaling 16 1.44e-01 2.11e-01 3.31e-01
Ubiquitin-dependent degradation of Cyclin D 50 1.46e-01 1.19e-01 3.32e-01
TP53 Regulates Transcription of DNA Repair Genes 61 1.46e-01 -1.08e-01 3.32e-01
CDC6 association with the ORC:origin complex 11 1.46e-01 -2.53e-01 3.32e-01
Signaling by FGFR2 in disease 32 1.46e-01 -1.48e-01 3.32e-01
RNA Polymerase I Promoter Opening 19 1.46e-01 1.92e-01 3.32e-01
Kinesins 39 1.47e-01 -1.34e-01 3.32e-01
BMAL1:CLOCK,NPAS2 activates circadian gene expression 25 1.47e-01 1.67e-01 3.32e-01
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 53 1.47e-01 1.15e-01 3.32e-01
Constitutive Signaling by NOTCH1 PEST Domain Mutants 53 1.47e-01 1.15e-01 3.32e-01
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 53 1.47e-01 1.15e-01 3.32e-01
Signaling by NOTCH1 PEST Domain Mutants in Cancer 53 1.47e-01 1.15e-01 3.32e-01
Signaling by NOTCH1 in Cancer 53 1.47e-01 1.15e-01 3.32e-01
Cyclin A/B1/B2 associated events during G2/M transition 25 1.48e-01 -1.67e-01 3.32e-01
ATF4 activates genes in response to endoplasmic reticulum stress 25 1.48e-01 -1.67e-01 3.32e-01
Disease 1350 1.48e-01 -2.35e-02 3.32e-01
Cytochrome c-mediated apoptotic response 13 1.50e-01 2.30e-01 3.36e-01
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 22 1.52e-01 1.77e-01 3.39e-01
Interleukin-2 family signaling 38 1.54e-01 1.34e-01 3.43e-01
Regulation of RUNX3 expression and activity 55 1.54e-01 1.11e-01 3.43e-01
PI-3K cascade:FGFR2 12 1.54e-01 -2.37e-01 3.43e-01
FOXO-mediated transcription of cell cycle genes 15 1.55e-01 -2.12e-01 3.44e-01
Post-translational protein modification 1189 1.55e-01 2.45e-02 3.44e-01
Acyl chain remodelling of PC 19 1.56e-01 1.88e-01 3.45e-01
Phase II - Conjugation of compounds 67 1.56e-01 1.00e-01 3.45e-01
Assembly and cell surface presentation of NMDA receptors 18 1.57e-01 -1.93e-01 3.46e-01
Diseases associated with glycosylation precursor biosynthesis 18 1.58e-01 1.92e-01 3.46e-01
Apoptotic execution phase 45 1.58e-01 1.22e-01 3.46e-01
Interleukin-17 signaling 68 1.58e-01 9.90e-02 3.46e-01
Carnitine metabolism 10 1.58e-01 2.58e-01 3.46e-01
Downregulation of TGF-beta receptor signaling 26 1.58e-01 -1.60e-01 3.46e-01
Adenylate cyclase inhibitory pathway 11 1.59e-01 2.45e-01 3.46e-01
IRAK1 recruits IKK complex 10 1.59e-01 2.57e-01 3.46e-01
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 10 1.59e-01 2.57e-01 3.46e-01
Nucleotide salvage 21 1.59e-01 1.77e-01 3.47e-01
NOTCH2 intracellular domain regulates transcription 11 1.61e-01 2.44e-01 3.49e-01
Activation of gene expression by SREBF (SREBP) 42 1.62e-01 1.25e-01 3.51e-01
Chromatin modifying enzymes 217 1.63e-01 -5.50e-02 3.51e-01
Chromatin organization 217 1.63e-01 -5.50e-02 3.51e-01
Interleukin-10 signaling 34 1.63e-01 1.38e-01 3.52e-01
Activation of G protein gated Potassium channels 19 1.66e-01 1.84e-01 3.55e-01
G protein gated Potassium channels 19 1.66e-01 1.84e-01 3.55e-01
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 19 1.66e-01 1.84e-01 3.55e-01
Nuclear Envelope (NE) Reassembly 69 1.66e-01 -9.65e-02 3.55e-01
Inhibition of replication initiation of damaged DNA by RB1/E2F1 13 1.66e-01 -2.22e-01 3.55e-01
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12 1.68e-01 2.30e-01 3.59e-01
Dectin-1 mediated noncanonical NF-kB signaling 58 1.69e-01 1.04e-01 3.60e-01
RORA activates gene expression 18 1.69e-01 1.87e-01 3.60e-01
Polo-like kinase mediated events 16 1.70e-01 -1.98e-01 3.61e-01
GPCR downstream signalling 493 1.70e-01 3.61e-02 3.62e-01
Asymmetric localization of PCP proteins 60 1.71e-01 1.02e-01 3.62e-01
Signaling by FGFR3 in disease 13 1.73e-01 -2.18e-01 3.65e-01
Signaling by FGFR3 point mutants in cancer 13 1.73e-01 -2.18e-01 3.65e-01
Activation of NF-kappaB in B cells 65 1.73e-01 9.77e-02 3.65e-01
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14 1.73e-01 -2.10e-01 3.65e-01
Stabilization of p53 54 1.74e-01 1.07e-01 3.66e-01
NOTCH3 Activation and Transmission of Signal to the Nucleus 23 1.76e-01 1.63e-01 3.69e-01
NOTCH4 Intracellular Domain Regulates Transcription 17 1.77e-01 1.89e-01 3.71e-01
SUMOylation of DNA methylation proteins 16 1.78e-01 -1.95e-01 3.72e-01
Non-integrin membrane-ECM interactions 37 1.78e-01 -1.28e-01 3.72e-01
Autodegradation of the E3 ubiquitin ligase COP1 49 1.79e-01 1.11e-01 3.73e-01
Signaling by FGFR1 38 1.79e-01 1.26e-01 3.73e-01
The phototransduction cascade 25 1.79e-01 -1.55e-01 3.73e-01
Bile acid and bile salt metabolism 29 1.80e-01 1.44e-01 3.73e-01
Metabolism of nucleotides 86 1.82e-01 -8.33e-02 3.78e-01
ZBP1(DAI) mediated induction of type I IFNs 20 1.82e-01 1.72e-01 3.78e-01
RET signaling 32 1.83e-01 1.36e-01 3.78e-01
Mitotic Prophase 98 1.83e-01 -7.78e-02 3.78e-01
Oncogene Induced Senescence 33 1.83e-01 1.34e-01 3.78e-01
Pyrimidine salvage 10 1.84e-01 2.43e-01 3.78e-01
Deactivation of the beta-catenin transactivating complex 36 1.84e-01 -1.28e-01 3.78e-01
mTORC1-mediated signalling 24 1.84e-01 1.57e-01 3.78e-01
Adherens junctions interactions 18 1.86e-01 1.80e-01 3.80e-01
Acetylcholine Neurotransmitter Release Cycle 11 1.86e-01 -2.30e-01 3.80e-01
Cytosolic sulfonation of small molecules 18 1.87e-01 1.80e-01 3.80e-01
Presynaptic function of Kainate receptors 18 1.87e-01 1.80e-01 3.80e-01
O-linked glycosylation of mucins 47 1.87e-01 1.11e-01 3.80e-01
FOXO-mediated transcription of cell death genes 16 1.87e-01 1.91e-01 3.80e-01
Formation of ATP by chemiosmotic coupling 18 1.88e-01 1.79e-01 3.83e-01
Apoptotic factor-mediated response 18 1.89e-01 1.79e-01 3.84e-01
RA biosynthesis pathway 13 1.90e-01 -2.10e-01 3.84e-01
Sialic acid metabolism 28 1.91e-01 1.43e-01 3.85e-01
PLC beta mediated events 43 1.92e-01 1.15e-01 3.86e-01
ERK/MAPK targets 22 1.92e-01 1.61e-01 3.86e-01
Frs2-mediated activation 11 1.92e-01 2.27e-01 3.86e-01
FGFR1 mutant receptor activation 23 1.93e-01 1.57e-01 3.88e-01
FGFR2 mutant receptor activation 22 1.93e-01 -1.60e-01 3.88e-01
Metabolism of polyamines 57 1.94e-01 9.94e-02 3.89e-01
GLI3 is processed to GLI3R by the proteasome 57 1.97e-01 9.88e-02 3.94e-01
Amyloid fiber formation 51 1.97e-01 1.04e-01 3.94e-01
RUNX2 regulates bone development 23 1.98e-01 1.55e-01 3.95e-01
InlB-mediated entry of Listeria monocytogenes into host cell 12 1.98e-01 2.14e-01 3.95e-01
Metabolism of fat-soluble vitamins 28 1.99e-01 1.40e-01 3.95e-01
G alpha (12/13) signalling events 69 1.99e-01 8.93e-02 3.96e-01
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 20 2.02e-01 -1.65e-01 4.00e-01
G-protein mediated events 44 2.02e-01 1.11e-01 4.00e-01
Vpu mediated degradation of CD4 50 2.02e-01 1.04e-01 4.00e-01
RMTs methylate histone arginines 37 2.03e-01 -1.21e-01 4.01e-01
Negative epigenetic regulation of rRNA expression 62 2.05e-01 -9.32e-02 4.03e-01
Platelet Aggregation (Plug Formation) 28 2.08e-01 1.38e-01 4.08e-01
MAP kinase activation 63 2.08e-01 9.17e-02 4.08e-01
Degradation of AXIN 53 2.08e-01 1.00e-01 4.08e-01
Signaling by NOTCH3 42 2.08e-01 1.12e-01 4.08e-01
Class I peroxisomal membrane protein import 20 2.09e-01 -1.62e-01 4.09e-01
Assembly Of The HIV Virion 15 2.09e-01 1.87e-01 4.09e-01
DNA Damage Recognition in GG-NER 38 2.10e-01 -1.17e-01 4.11e-01
TRAF6 mediated IRF7 activation 15 2.13e-01 1.86e-01 4.16e-01
HIV Infection 224 2.14e-01 -4.82e-02 4.16e-01
PI Metabolism 80 2.14e-01 8.04e-02 4.16e-01
Inwardly rectifying K+ channels 23 2.15e-01 1.49e-01 4.18e-01
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol 16 2.16e-01 1.79e-01 4.19e-01
Nuclear Events (kinase and transcription factor activation) 53 2.16e-01 9.82e-02 4.19e-01
UCH proteinases 86 2.17e-01 7.70e-02 4.19e-01
Interleukin-37 signaling 19 2.17e-01 1.63e-01 4.20e-01
FCGR3A-mediated phagocytosis 121 2.19e-01 -6.48e-02 4.20e-01
Leishmania phagocytosis 121 2.19e-01 -6.48e-02 4.20e-01
Parasite infection 121 2.19e-01 -6.48e-02 4.20e-01
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 14 2.19e-01 1.90e-01 4.21e-01
Macroautophagy 110 2.20e-01 6.77e-02 4.21e-01
MAPK6/MAPK4 signaling 82 2.21e-01 7.82e-02 4.23e-01
Cardiac conduction 86 2.21e-01 7.63e-02 4.23e-01
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 72 2.22e-01 8.33e-02 4.23e-01
DCC mediated attractive signaling 13 2.24e-01 -1.95e-01 4.26e-01
Erythrocytes take up carbon dioxide and release oxygen 12 2.24e-01 2.03e-01 4.26e-01
O2/CO2 exchange in erythrocytes 12 2.24e-01 2.03e-01 4.26e-01
Butyrophilin (BTN) family interactions 10 2.25e-01 -2.22e-01 4.27e-01
Processing of SMDT1 15 2.26e-01 -1.81e-01 4.28e-01
Collagen biosynthesis and modifying enzymes 48 2.26e-01 1.01e-01 4.28e-01
Syndecan interactions 19 2.27e-01 -1.60e-01 4.28e-01
Caspase activation via Death Receptors in the presence of ligand 16 2.27e-01 1.74e-01 4.29e-01
Reproduction 80 2.31e-01 -7.75e-02 4.35e-01
Assembly of active LPL and LIPC lipase complexes 10 2.33e-01 2.18e-01 4.39e-01
Negative regulation of FGFR1 signaling 24 2.33e-01 1.41e-01 4.39e-01
Signaling by BMP 21 2.34e-01 -1.50e-01 4.39e-01
Complex I biogenesis 55 2.36e-01 9.24e-02 4.42e-01
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 124 2.38e-01 6.14e-02 4.45e-01
Membrane binding and targetting of GAG proteins 13 2.40e-01 1.88e-01 4.47e-01
Synthesis And Processing Of GAG, GAGPOL Polyproteins 13 2.40e-01 1.88e-01 4.47e-01
Defective B3GALT6 causes EDSP2 and SEMDJL1 11 2.42e-01 -2.04e-01 4.51e-01
SARS-CoV-1 Infection 47 2.42e-01 9.86e-02 4.51e-01
Citric acid cycle (TCA cycle) 22 2.43e-01 1.44e-01 4.51e-01
Inactivation, recovery and regulation of the phototransduction cascade 24 2.43e-01 -1.38e-01 4.51e-01
tRNA processing in the mitochondrion 30 2.43e-01 -1.23e-01 4.51e-01
Signaling by Activin 10 2.44e-01 -2.13e-01 4.51e-01
TRAF3-dependent IRF activation pathway 13 2.44e-01 1.87e-01 4.51e-01
IKK complex recruitment mediated by RIP1 23 2.44e-01 1.40e-01 4.51e-01
Triglyceride catabolism 16 2.45e-01 1.68e-01 4.52e-01
Switching of origins to a post-replicative state 89 2.46e-01 -7.12e-02 4.52e-01
Common Pathway of Fibrin Clot Formation 14 2.48e-01 1.78e-01 4.55e-01
Signaling by cytosolic FGFR1 fusion mutants 17 2.48e-01 1.62e-01 4.55e-01
Cargo trafficking to the periciliary membrane 47 2.49e-01 -9.72e-02 4.55e-01
ABC transporters in lipid homeostasis 14 2.49e-01 -1.78e-01 4.55e-01
Constitutive Signaling by Aberrant PI3K in Cancer 54 2.50e-01 -9.06e-02 4.55e-01
Transport of vitamins, nucleosides, and related molecules 33 2.50e-01 1.16e-01 4.55e-01
The citric acid (TCA) cycle and respiratory electron transport 172 2.50e-01 5.09e-02 4.55e-01
Ras activation upon Ca2+ influx through NMDA receptor 15 2.50e-01 -1.72e-01 4.55e-01
FGFR2 alternative splicing 25 2.50e-01 -1.33e-01 4.55e-01
TNFR1-induced proapoptotic signaling 12 2.52e-01 -1.91e-01 4.58e-01
Mitotic Telophase/Cytokinesis 13 2.53e-01 -1.83e-01 4.59e-01
G beta:gamma signalling through CDC42 17 2.54e-01 1.60e-01 4.61e-01
Trafficking and processing of endosomal TLR 13 2.55e-01 1.82e-01 4.61e-01
RUNX3 regulates NOTCH signaling 14 2.55e-01 1.76e-01 4.61e-01
Autodegradation of Cdh1 by Cdh1:APC/C 64 2.55e-01 8.22e-02 4.61e-01
Tryptophan catabolism 12 2.58e-01 1.88e-01 4.66e-01
Signaling by NOTCH2 30 2.60e-01 1.19e-01 4.67e-01
Downstream signaling of activated FGFR2 19 2.60e-01 -1.49e-01 4.67e-01
EPHA-mediated growth cone collapse 13 2.60e-01 1.80e-01 4.68e-01
Synthesis of PIPs at the plasma membrane 52 2.64e-01 8.96e-02 4.73e-01
Negative regulators of DDX58/IFIH1 signaling 34 2.65e-01 -1.11e-01 4.74e-01
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 26 2.66e-01 -1.26e-01 4.75e-01
Arachidonic acid metabolism 43 2.66e-01 9.81e-02 4.75e-01
RIP-mediated NFkB activation via ZBP1 17 2.67e-01 1.56e-01 4.76e-01
Striated Muscle Contraction 23 2.70e-01 1.33e-01 4.81e-01
Phosphorylation of the APC/C 20 2.70e-01 -1.42e-01 4.81e-01
Processing and activation of SUMO 10 2.72e-01 -2.01e-01 4.82e-01
Regulation of TP53 Activity through Association with Co-factors 11 2.72e-01 -1.91e-01 4.82e-01
Biological oxidations 135 2.72e-01 5.47e-02 4.82e-01
Intracellular signaling by second messengers 271 2.73e-01 3.87e-02 4.82e-01
TRAF6 mediated NF-kB activation 23 2.73e-01 1.32e-01 4.82e-01
CLEC7A (Dectin-1) signaling 96 2.74e-01 6.46e-02 4.84e-01
Triglyceride metabolism 25 2.77e-01 1.26e-01 4.88e-01
The role of GTSE1 in G2/M progression after G2 checkpoint 58 2.77e-01 8.25e-02 4.88e-01
Degradation of beta-catenin by the destruction complex 83 2.77e-01 6.90e-02 4.88e-01
Signaling by FGFR2 60 2.81e-01 -8.06e-02 4.92e-01
Formation of apoptosome 11 2.81e-01 1.88e-01 4.92e-01
Regulation of the apoptosome activity 11 2.81e-01 1.88e-01 4.92e-01
SARS-CoV-2 Infection 63 2.82e-01 7.83e-02 4.94e-01
HDACs deacetylate histones 47 2.83e-01 9.05e-02 4.95e-01
IRF3-mediated induction of type I IFN 12 2.83e-01 -1.79e-01 4.95e-01
Transcriptional regulation of granulopoiesis 46 2.84e-01 9.13e-02 4.95e-01
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 43 2.84e-01 -9.43e-02 4.95e-01
GP1b-IX-V activation signalling 10 2.85e-01 -1.95e-01 4.95e-01
Post-translational modification: synthesis of GPI-anchored proteins 57 2.85e-01 8.19e-02 4.95e-01
Nucleobase catabolism 28 2.87e-01 1.16e-01 4.98e-01
Respiratory electron transport 101 2.87e-01 6.13e-02 4.98e-01
EGFR downregulation 27 2.88e-01 1.18e-01 4.99e-01
FRS-mediated FGFR2 signaling 14 2.90e-01 -1.63e-01 5.01e-01
Post-chaperonin tubulin folding pathway 19 2.91e-01 1.40e-01 5.02e-01
Glyoxylate metabolism and glycine degradation 24 2.92e-01 -1.24e-01 5.02e-01
Glucagon signaling in metabolic regulation 27 2.92e-01 1.17e-01 5.02e-01
PIP3 activates AKT signaling 239 2.92e-01 3.95e-02 5.03e-01
Peroxisomal protein import 57 2.96e-01 8.01e-02 5.07e-01
PI-3K cascade:FGFR4 10 2.97e-01 -1.91e-01 5.08e-01
ABC-family proteins mediated transport 93 2.97e-01 6.26e-02 5.08e-01
N-Glycan antennae elongation 13 2.99e-01 -1.67e-01 5.10e-01
Eicosanoid ligand-binding receptors 13 3.02e-01 -1.65e-01 5.15e-01
SHC-mediated cascade:FGFR2 12 3.03e-01 -1.72e-01 5.16e-01
APC/C:Cdc20 mediated degradation of Securin 66 3.03e-01 7.33e-02 5.16e-01
Beta-catenin phosphorylation cascade 17 3.03e-01 1.44e-01 5.16e-01
Voltage gated Potassium channels 25 3.04e-01 1.19e-01 5.17e-01
Apoptotic cleavage of cellular proteins 34 3.04e-01 1.02e-01 5.17e-01
Synthesis, secretion, and deacylation of Ghrelin 12 3.06e-01 -1.71e-01 5.19e-01
WNT ligand biogenesis and trafficking 21 3.07e-01 1.29e-01 5.20e-01
Glycogen storage diseases 13 3.08e-01 1.63e-01 5.21e-01
Death Receptor Signalling 132 3.10e-01 5.11e-02 5.22e-01
Sphingolipid de novo biosynthesis 42 3.10e-01 9.04e-02 5.22e-01
G beta:gamma signalling through PLC beta 17 3.11e-01 1.42e-01 5.22e-01
HuR (ELAVL1) binds and stabilizes mRNA 10 3.11e-01 1.85e-01 5.22e-01
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 32 3.11e-01 1.03e-01 5.22e-01
Nicotinate metabolism 25 3.12e-01 1.17e-01 5.22e-01
Basigin interactions 23 3.12e-01 -1.22e-01 5.22e-01
DNA Double Strand Break Response 47 3.12e-01 -8.52e-02 5.22e-01
DAP12 interactions 39 3.13e-01 9.35e-02 5.22e-01
Phase 4 - resting membrane potential 10 3.13e-01 1.84e-01 5.22e-01
Signaling by Hedgehog 120 3.14e-01 5.33e-02 5.23e-01
Regulation of TP53 Activity through Methylation 19 3.14e-01 -1.33e-01 5.23e-01
Cytochrome P450 - arranged by substrate type 34 3.16e-01 9.94e-02 5.25e-01
Gastrin-CREB signalling pathway via PKC and MAPK 14 3.20e-01 1.53e-01 5.32e-01
Glycogen metabolism 23 3.20e-01 1.20e-01 5.32e-01
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion 14 3.22e-01 1.53e-01 5.33e-01
Interleukin receptor SHC signaling 23 3.22e-01 1.19e-01 5.33e-01
Calnexin/calreticulin cycle 26 3.22e-01 1.12e-01 5.33e-01
Activation of BH3-only proteins 29 3.25e-01 -1.06e-01 5.37e-01
Metabolic disorders of biological oxidation enzymes 25 3.29e-01 1.13e-01 5.42e-01
SUMOylation of intracellular receptors 25 3.29e-01 1.13e-01 5.42e-01
Caspase-mediated cleavage of cytoskeletal proteins 12 3.29e-01 1.63e-01 5.42e-01
Glutamate Neurotransmitter Release Cycle 20 3.30e-01 -1.26e-01 5.42e-01
NOD1/2 Signaling Pathway 32 3.30e-01 9.95e-02 5.42e-01
Signaling by NODAL 13 3.30e-01 -1.56e-01 5.42e-01
Unblocking of NMDA receptors, glutamate binding and activation 12 3.35e-01 -1.61e-01 5.49e-01
Signaling by Hippo 18 3.36e-01 1.31e-01 5.49e-01
Oxidative Stress Induced Senescence 79 3.36e-01 6.26e-02 5.49e-01
Interleukin-6 signaling 10 3.36e-01 1.76e-01 5.49e-01
O-glycosylation of TSR domain-containing proteins 26 3.37e-01 -1.09e-01 5.49e-01
G beta:gamma signalling through BTK 15 3.37e-01 1.43e-01 5.49e-01
Interleukin-27 signaling 11 3.38e-01 1.67e-01 5.50e-01
Negative regulation of NMDA receptor-mediated neuronal transmission 14 3.39e-01 -1.48e-01 5.50e-01
RNA Polymerase I Promoter Escape 44 3.39e-01 -8.33e-02 5.50e-01
Apoptosis induced DNA fragmentation 10 3.42e-01 1.74e-01 5.54e-01
Signaling by FGFR4 in disease 11 3.42e-01 -1.65e-01 5.54e-01
TAK1 activates NFkB by phosphorylation and activation of IKKs complex 27 3.44e-01 1.05e-01 5.55e-01
Nonhomologous End-Joining (NHEJ) 42 3.44e-01 -8.44e-02 5.55e-01
Suppression of phagosomal maturation 12 3.44e-01 1.58e-01 5.56e-01
IRAK2 mediated activation of TAK1 complex 10 3.46e-01 -1.72e-01 5.57e-01
Formation of tubulin folding intermediates by CCT/TriC 22 3.46e-01 -1.16e-01 5.58e-01
HSP90 chaperone cycle for steroid hormone receptors (SHR) 36 3.47e-01 9.05e-02 5.58e-01
N-glycan antennae elongation in the medial/trans-Golgi 21 3.48e-01 -1.18e-01 5.58e-01
Synthesis of IP3 and IP4 in the cytosol 22 3.48e-01 1.15e-01 5.58e-01
Signaling by ERBB2 KD Mutants 20 3.48e-01 -1.21e-01 5.58e-01
Glucose metabolism 84 3.52e-01 5.87e-02 5.63e-01
Regulation of actin dynamics for phagocytic cup formation 123 3.55e-01 -4.83e-02 5.67e-01
HSF1-dependent transactivation 29 3.56e-01 -9.91e-02 5.67e-01
IRS-related events triggered by IGF1R 35 3.56e-01 -9.02e-02 5.67e-01
GRB2 events in ERBB2 signaling 11 3.58e-01 -1.60e-01 5.70e-01
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 37 3.60e-01 -8.70e-02 5.72e-01
Defective EXT1 causes exostoses 1, TRPS2 and CHDS 10 3.61e-01 -1.67e-01 5.73e-01
Defective EXT2 causes exostoses 2 10 3.61e-01 -1.67e-01 5.73e-01
Defective B3GAT3 causes JDSSDHD 11 3.62e-01 -1.59e-01 5.73e-01
Lysosphingolipid and LPA receptors 11 3.62e-01 -1.59e-01 5.73e-01
Surfactant metabolism 21 3.63e-01 1.15e-01 5.74e-01
Aquaporin-mediated transport 37 3.63e-01 8.64e-02 5.74e-01
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 46 3.64e-01 -7.74e-02 5.74e-01
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15 3.67e-01 1.35e-01 5.78e-01
Prolactin receptor signaling 11 3.69e-01 -1.56e-01 5.81e-01
PKA activation in glucagon signalling 14 3.72e-01 1.38e-01 5.85e-01
IRS-mediated signalling 34 3.72e-01 -8.84e-02 5.85e-01
TP53 Regulates Transcription of Death Receptors and Ligands 11 3.74e-01 -1.55e-01 5.87e-01
Diseases of metabolism 189 3.75e-01 3.75e-02 5.87e-01
EGR2 and SOX10-mediated initiation of Schwann cell myelination 22 3.76e-01 1.09e-01 5.88e-01
Vitamin B5 (pantothenate) metabolism 17 3.77e-01 1.24e-01 5.89e-01
SCF-beta-TrCP mediated degradation of Emi1 53 3.77e-01 7.01e-02 5.89e-01
Lysine catabolism 11 3.78e-01 1.54e-01 5.89e-01
p130Cas linkage to MAPK signaling for integrins 11 3.78e-01 1.54e-01 5.89e-01
Signaling by ERBB2 TMD/JMD mutants 17 3.79e-01 -1.23e-01 5.89e-01
Nuclear Receptor transcription pathway 36 3.81e-01 -8.43e-02 5.90e-01
Orc1 removal from chromatin 69 3.81e-01 -6.09e-02 5.90e-01
Protein methylation 15 3.81e-01 -1.31e-01 5.90e-01
GAB1 signalosome 15 3.81e-01 1.31e-01 5.90e-01
Netrin-1 signaling 40 3.82e-01 -7.99e-02 5.90e-01
Ca-dependent events 29 3.82e-01 9.38e-02 5.90e-01
Signaling by TGFB family members 91 3.83e-01 -5.30e-02 5.91e-01
p53-Dependent G1 DNA Damage Response 63 3.84e-01 6.35e-02 5.91e-01
p53-Dependent G1/S DNA damage checkpoint 63 3.84e-01 6.35e-02 5.91e-01
Inositol phosphate metabolism 42 3.84e-01 7.76e-02 5.91e-01
MET activates RAS signaling 10 3.85e-01 1.59e-01 5.92e-01
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 36 3.87e-01 8.33e-02 5.94e-01
Regulation of beta-cell development 19 3.88e-01 1.14e-01 5.94e-01
Miscellaneous transport and binding events 20 3.89e-01 -1.11e-01 5.95e-01
Metabolism of cofactors 19 3.94e-01 1.13e-01 6.03e-01
Dopamine Neurotransmitter Release Cycle 20 3.95e-01 -1.10e-01 6.03e-01
Attenuation phase 23 3.95e-01 -1.02e-01 6.03e-01
G-protein activation 23 4.00e-01 1.01e-01 6.10e-01
ADP signalling through P2Y purinoceptor 12 18 4.01e-01 1.14e-01 6.10e-01
Synthesis of PIPs at the Golgi membrane 16 4.03e-01 1.21e-01 6.13e-01
Platelet calcium homeostasis 21 4.03e-01 1.05e-01 6.13e-01
CTLA4 inhibitory signaling 21 4.04e-01 -1.05e-01 6.14e-01
Signaling by Non-Receptor Tyrosine Kinases 48 4.07e-01 6.93e-02 6.16e-01
Signaling by PTK6 48 4.07e-01 6.93e-02 6.16e-01
ER Quality Control Compartment (ERQC) 21 4.08e-01 1.04e-01 6.18e-01
Defective B4GALT7 causes EDS, progeroid type 11 4.09e-01 -1.44e-01 6.18e-01
Interaction between L1 and Ankyrins 22 4.11e-01 -1.01e-01 6.19e-01
Constitutive Signaling by AKT1 E17K in Cancer 25 4.11e-01 9.51e-02 6.19e-01
Resolution of D-loop Structures through Holliday Junction Intermediates 32 4.11e-01 -8.40e-02 6.19e-01
PKMTs methylate histone lysines 44 4.12e-01 -7.15e-02 6.19e-01
Keratan sulfate/keratin metabolism 27 4.12e-01 9.13e-02 6.19e-01
Signaling by FGFR1 in disease 30 4.12e-01 8.65e-02 6.19e-01
NoRC negatively regulates rRNA expression 59 4.13e-01 -6.16e-02 6.19e-01
Retrograde transport at the Trans-Golgi-Network 49 4.14e-01 6.75e-02 6.19e-01
Thromboxane signalling through TP receptor 20 4.14e-01 1.06e-01 6.19e-01
Uptake and actions of bacterial toxins 27 4.14e-01 9.07e-02 6.19e-01
Interleukin-12 family signaling 53 4.15e-01 6.47e-02 6.20e-01
Protein folding 90 4.16e-01 4.97e-02 6.20e-01
G alpha (z) signalling events 36 4.16e-01 7.84e-02 6.20e-01
Molecules associated with elastic fibres 22 4.19e-01 -9.96e-02 6.23e-01
Estrogen-dependent gene expression 99 4.21e-01 -4.68e-02 6.25e-01
Aberrant regulation of mitotic cell cycle due to RB1 defects 36 4.21e-01 -7.74e-02 6.25e-01
Diseases of mitotic cell cycle 36 4.21e-01 -7.74e-02 6.25e-01
Signaling by ERBB2 in Cancer 21 4.23e-01 -1.01e-01 6.26e-01
DNA methylation 20 4.23e-01 1.03e-01 6.26e-01
Downregulation of ERBB2 signaling 24 4.24e-01 -9.43e-02 6.27e-01
PI3K Cascade 30 4.25e-01 -8.42e-02 6.27e-01
Regulation of mRNA stability by proteins that bind AU-rich elements 87 4.27e-01 4.93e-02 6.29e-01
Downstream signaling of activated FGFR4 17 4.27e-01 -1.11e-01 6.29e-01
Collagen chain trimerization 27 4.29e-01 -8.80e-02 6.31e-01
Interleukin-35 Signalling 12 4.29e-01 -1.32e-01 6.31e-01
Repression of WNT target genes 14 4.30e-01 -1.22e-01 6.32e-01
Diseases of programmed cell death 28 4.32e-01 8.58e-02 6.33e-01
TP53 Regulates Transcription of Caspase Activators and Caspases 11 4.32e-01 -1.37e-01 6.33e-01
Cell death signalling via NRAGE, NRIF and NADE 70 4.32e-01 5.43e-02 6.33e-01
Aflatoxin activation and detoxification 14 4.41e-01 1.19e-01 6.45e-01
Rap1 signalling 13 4.41e-01 1.23e-01 6.45e-01
Translation of Replicase and Assembly of the Replication Transcription Complex 12 4.42e-01 1.28e-01 6.45e-01
Interleukin-12 signaling 44 4.43e-01 6.69e-02 6.45e-01
Synthesis of PE 12 4.43e-01 -1.28e-01 6.45e-01
Metabolism of vitamins and cofactors 155 4.43e-01 3.57e-02 6.45e-01
Acyl chain remodelling of PI 10 4.44e-01 1.40e-01 6.45e-01
NOTCH3 Intracellular Domain Regulates Transcription 20 4.48e-01 9.79e-02 6.51e-01
Pregnenolone biosynthesis 10 4.53e-01 1.37e-01 6.56e-01
Developmental Biology 727 4.53e-01 -1.64e-02 6.56e-01
Defective B3GALTL causes Peters-plus syndrome (PpS) 25 4.54e-01 -8.65e-02 6.56e-01
Chaperonin-mediated protein folding 84 4.54e-01 4.73e-02 6.56e-01
Signaling by ERBB2 ECD mutants 15 4.58e-01 -1.11e-01 6.61e-01
Meiotic synapsis 45 4.58e-01 -6.39e-02 6.61e-01
HCMV Infection 96 4.59e-01 -4.37e-02 6.61e-01
Regulation of TNFR1 signaling 34 4.60e-01 -7.31e-02 6.63e-01
Peroxisomal lipid metabolism 27 4.62e-01 8.18e-02 6.63e-01
Signaling by KIT in disease 20 4.62e-01 -9.50e-02 6.63e-01
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants 20 4.62e-01 -9.50e-02 6.63e-01
Signaling by TGF-beta Receptor Complex 72 4.67e-01 -4.95e-02 6.69e-01
Phase 0 - rapid depolarisation 22 4.68e-01 -8.94e-02 6.69e-01
Prefoldin mediated transfer of substrate to CCT/TriC 26 4.68e-01 -8.22e-02 6.69e-01
IGF1R signaling cascade 36 4.70e-01 -6.96e-02 6.71e-01
GRB2:SOS provides linkage to MAPK signaling for Integrins 12 4.70e-01 1.20e-01 6.71e-01
Formation of Senescence-Associated Heterochromatin Foci (SAHF) 13 4.72e-01 1.15e-01 6.73e-01
Transcription of the HIV genome 67 4.73e-01 -5.08e-02 6.73e-01
N-glycan trimming in the ER and Calnexin/Calreticulin cycle 35 4.73e-01 7.01e-02 6.73e-01
Metal ion SLC transporters 21 4.74e-01 9.03e-02 6.73e-01
Regulation of KIT signaling 15 4.75e-01 1.06e-01 6.75e-01
Class A/1 (Rhodopsin-like receptors) 162 4.77e-01 -3.24e-02 6.76e-01
TNFR1-induced NFkappaB signaling pathway 25 4.77e-01 -8.22e-02 6.76e-01
p38MAPK events 13 4.79e-01 1.13e-01 6.77e-01
SUMOylation of transcription factors 16 4.80e-01 1.02e-01 6.78e-01
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) 12 4.80e-01 -1.18e-01 6.78e-01
NOTCH1 Intracellular Domain Regulates Transcription 44 4.81e-01 6.13e-02 6.79e-01
CDK-mediated phosphorylation and removal of Cdc6 71 4.82e-01 4.83e-02 6.79e-01
Chaperone Mediated Autophagy 20 4.83e-01 -9.06e-02 6.80e-01
Regulation of RUNX2 expression and activity 66 4.84e-01 4.98e-02 6.81e-01
Phase I - Functionalization of compounds 63 4.84e-01 5.09e-02 6.81e-01
Estrogen-dependent nuclear events downstream of ESR-membrane signaling 22 4.85e-01 -8.60e-02 6.81e-01
TCF dependent signaling in response to WNT 165 4.87e-01 3.14e-02 6.82e-01
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane 22 4.87e-01 8.56e-02 6.82e-01
VEGFR2 mediated vascular permeability 27 4.88e-01 7.72e-02 6.82e-01
Vasopressin regulates renal water homeostasis via Aquaporins 34 4.88e-01 6.87e-02 6.82e-01
Regulation of innate immune responses to cytosolic DNA 14 4.91e-01 -1.06e-01 6.86e-01
Other semaphorin interactions 16 4.95e-01 9.85e-02 6.90e-01
Interleukin-20 family signaling 17 4.95e-01 9.55e-02 6.90e-01
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression 32 4.96e-01 -6.95e-02 6.90e-01
Listeria monocytogenes entry into host cells 17 4.96e-01 9.53e-02 6.90e-01
SHC1 events in EGFR signaling 12 4.98e-01 1.13e-01 6.91e-01
Norepinephrine Neurotransmitter Release Cycle 14 4.98e-01 -1.05e-01 6.91e-01
DARPP-32 events 22 4.98e-01 8.34e-02 6.91e-01
CD28 co-stimulation 33 5.00e-01 -6.79e-02 6.92e-01
Signaling by EGFR 46 5.00e-01 5.75e-02 6.92e-01
SCF(Skp2)-mediated degradation of p27/p21 60 5.01e-01 5.02e-02 6.93e-01
FRS-mediated FGFR4 signaling 12 5.02e-01 -1.12e-01 6.93e-01
Condensation of Prometaphase Chromosomes 11 5.04e-01 -1.16e-01 6.95e-01
Selective autophagy 58 5.07e-01 -5.04e-02 6.98e-01
CDT1 association with the CDC6:ORC:origin complex 57 5.11e-01 5.04e-02 7.03e-01
G1/S DNA Damage Checkpoints 65 5.16e-01 4.66e-02 7.09e-01
MAPK targets/ Nuclear events mediated by MAP kinases 31 5.16e-01 6.74e-02 7.09e-01
Disassembly of the destruction complex and recruitment of AXIN to the membrane 29 5.18e-01 6.93e-02 7.11e-01
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 11 5.19e-01 -1.12e-01 7.11e-01
RUNX2 regulates osteoblast differentiation 18 5.19e-01 8.78e-02 7.11e-01
Synaptic adhesion-like molecules 14 5.20e-01 9.93e-02 7.12e-01
Keratinization 32 5.21e-01 6.55e-02 7.12e-01
Signaling by FGFR2 IIIa TM 18 5.22e-01 -8.71e-02 7.13e-01
Endosomal/Vacuolar pathway 12 5.25e-01 -1.06e-01 7.16e-01
The canonical retinoid cycle in rods (twilight vision) 10 5.26e-01 1.16e-01 7.16e-01
ADORA2B mediated anti-inflammatory cytokines production 73 5.26e-01 -4.29e-02 7.16e-01
Resolution of D-Loop Structures 33 5.27e-01 -6.37e-02 7.17e-01
Interleukin-6 family signaling 18 5.28e-01 8.58e-02 7.18e-01
Glucagon-type ligand receptors 20 5.32e-01 -8.07e-02 7.22e-01
Metabolism of nitric oxide: NOS3 activation and regulation 12 5.34e-01 -1.04e-01 7.24e-01
Metabolism of Angiotensinogen to Angiotensins 11 5.36e-01 1.08e-01 7.25e-01
Degradation of cysteine and homocysteine 12 5.36e-01 1.03e-01 7.25e-01
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 36 5.38e-01 -5.93e-02 7.27e-01
TICAM1,TRAF6-dependent induction of TAK1 complex 11 5.38e-01 -1.07e-01 7.27e-01
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 16 5.39e-01 -8.86e-02 7.28e-01
SHC-mediated cascade:FGFR4 10 5.40e-01 -1.12e-01 7.28e-01
NOTCH2 Activation and Transmission of Signal to the Nucleus 20 5.41e-01 7.89e-02 7.29e-01
Termination of O-glycan biosynthesis 16 5.44e-01 8.75e-02 7.33e-01
GABA synthesis, release, reuptake and degradation 13 5.46e-01 -9.67e-02 7.34e-01
Nucleotide-like (purinergic) receptors 12 5.47e-01 -1.01e-01 7.34e-01
TNFR2 non-canonical NF-kB pathway 95 5.49e-01 -3.56e-02 7.37e-01
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 13 5.50e-01 -9.58e-02 7.37e-01
Synthesis of IP2, IP, and Ins in the cytosol 13 5.54e-01 9.47e-02 7.42e-01
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 18 5.56e-01 -8.02e-02 7.43e-01
CD209 (DC-SIGN) signaling 20 5.56e-01 7.60e-02 7.43e-01
PI3K events in ERBB2 signaling 11 5.58e-01 -1.02e-01 7.44e-01
NRAGE signals death through JNK 53 5.58e-01 4.65e-02 7.45e-01
Pyruvate metabolism and Citric Acid (TCA) cycle 52 5.61e-01 4.66e-02 7.48e-01
Gamma carboxylation, hypusine formation and arylsulfatase activation 34 5.62e-01 -5.75e-02 7.48e-01
Tie2 Signaling 16 5.64e-01 8.32e-02 7.51e-01
CD28 dependent Vav1 pathway 12 5.65e-01 9.59e-02 7.51e-01
Cyclin A:Cdk2-associated events at S phase entry 85 5.66e-01 -3.60e-02 7.51e-01
Integrin cell surface interactions 52 5.67e-01 4.59e-02 7.51e-01
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 29 5.67e-01 -6.14e-02 7.52e-01
Downregulation of SMAD2/3:SMAD4 transcriptional activity 23 5.70e-01 -6.85e-02 7.54e-01
Antigen processing: Ubiquitination & Proteasome degradation 288 5.70e-01 -1.95e-02 7.54e-01
SUMOylation of transcription cofactors 44 5.71e-01 -4.94e-02 7.54e-01
Branched-chain amino acid catabolism 21 5.72e-01 -7.13e-02 7.54e-01
Synthesis of substrates in N-glycan biosythesis 58 5.72e-01 4.29e-02 7.54e-01
Cellular Senescence 144 5.75e-01 2.71e-02 7.57e-01
Downstream signaling of activated FGFR3 16 5.75e-01 -8.09e-02 7.57e-01
Ion transport by P-type ATPases 42 5.78e-01 4.96e-02 7.60e-01
Fatty acyl-CoA biosynthesis 34 5.80e-01 5.48e-02 7.61e-01
Glutamate binding, activation of AMPA receptors and synaptic plasticity 20 5.80e-01 7.14e-02 7.61e-01
Trafficking of AMPA receptors 20 5.80e-01 7.14e-02 7.61e-01
ESR-mediated signaling 162 5.83e-01 -2.50e-02 7.64e-01
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) 12 5.86e-01 9.09e-02 7.65e-01
Diseases of hemostasis 12 5.86e-01 9.09e-02 7.65e-01
Senescence-Associated Secretory Phenotype (SASP) 66 5.86e-01 3.88e-02 7.65e-01
Class C/3 (Metabotropic glutamate/pheromone receptors) 12 5.92e-01 8.93e-02 7.73e-01
TRAF6-mediated induction of TAK1 complex within TLR4 complex 16 5.94e-01 7.71e-02 7.73e-01
Phase 2 - plateau phase 12 5.95e-01 8.86e-02 7.75e-01
Activation of BAD and translocation to mitochondria 15 5.98e-01 7.87e-02 7.77e-01
Cytosolic sensors of pathogen-associated DNA 62 5.98e-01 -3.87e-02 7.77e-01
Aberrant regulation of mitotic exit in cancer due to RB1 defects 20 6.01e-01 -6.76e-02 7.80e-01
Biosynthesis of specialized proresolving mediators (SPMs) 16 6.04e-01 7.50e-02 7.83e-01
Methylation 12 6.06e-01 -8.59e-02 7.85e-01
SARS-CoV Infections 139 6.07e-01 2.53e-02 7.86e-01
Factors involved in megakaryocyte development and platelet production 116 6.09e-01 2.75e-02 7.87e-01
Processing of Intronless Pre-mRNAs 19 6.09e-01 -6.77e-02 7.87e-01
Meiotic recombination 38 6.09e-01 -4.79e-02 7.87e-01
The role of Nef in HIV-1 replication and disease pathogenesis 28 6.13e-01 5.53e-02 7.89e-01
Extra-nuclear estrogen signaling 67 6.13e-01 -3.57e-02 7.89e-01
Sema3A PAK dependent Axon repulsion 16 6.13e-01 7.30e-02 7.89e-01
Regulation of APC/C activators between G1/S and early anaphase 79 6.18e-01 -3.25e-02 7.91e-01
Fertilization 12 6.18e-01 8.31e-02 7.91e-01
Negative regulation of FGFR3 signaling 20 6.18e-01 6.43e-02 7.91e-01
Activation of SMO 13 6.19e-01 7.97e-02 7.91e-01
CASP8 activity is inhibited 11 6.19e-01 -8.66e-02 7.91e-01
Dimerization of procaspase-8 11 6.19e-01 -8.66e-02 7.91e-01
Regulation by c-FLIP 11 6.19e-01 -8.66e-02 7.91e-01
PRC2 methylates histones and DNA 29 6.21e-01 -5.31e-02 7.92e-01
Neurexins and neuroligins 37 6.22e-01 -4.68e-02 7.92e-01
mRNA Capping 29 6.22e-01 -5.28e-02 7.92e-01
Activation of NMDA receptors and postsynaptic events 58 6.23e-01 -3.73e-02 7.92e-01
APC/C-mediated degradation of cell cycle proteins 86 6.24e-01 -3.06e-02 7.92e-01
Regulation of mitotic cell cycle 86 6.24e-01 -3.06e-02 7.92e-01
Downregulation of ERBB2:ERBB3 signaling 12 6.24e-01 -8.16e-02 7.92e-01
Cytokine Signaling in Immune system 735 6.25e-01 1.06e-02 7.92e-01
Cellular hexose transport 15 6.25e-01 -7.29e-02 7.92e-01
Serotonin Neurotransmitter Release Cycle 15 6.29e-01 -7.21e-02 7.96e-01
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 24 6.29e-01 -5.70e-02 7.96e-01
Metalloprotease DUBs 21 6.31e-01 6.06e-02 7.98e-01
Aggrephagy 22 6.32e-01 -5.89e-02 7.99e-01
TGF-beta receptor signaling activates SMADs 32 6.36e-01 -4.84e-02 8.02e-01
Heparan sulfate/heparin (HS-GAG) metabolism 37 6.40e-01 4.44e-02 8.07e-01
Signaling by Retinoic Acid 31 6.42e-01 -4.82e-02 8.09e-01
Synthesis of bile acids and bile salts 24 6.44e-01 5.45e-02 8.09e-01
Incretin synthesis, secretion, and inactivation 10 6.45e-01 -8.42e-02 8.09e-01
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) 10 6.45e-01 -8.42e-02 8.09e-01
Synthesis of PIPs at the late endosome membrane 11 6.45e-01 8.03e-02 8.09e-01
Antigen Presentation: Folding, assembly and peptide loading of class I MHC 25 6.52e-01 5.21e-02 8.17e-01
DNA Damage/Telomere Stress Induced Senescence 44 6.52e-01 -3.93e-02 8.17e-01
RNA polymerase II transcribes snRNA genes 72 6.57e-01 3.03e-02 8.21e-01
Association of TriC/CCT with target proteins during biosynthesis 37 6.57e-01 -4.22e-02 8.21e-01
MicroRNA (miRNA) biogenesis 24 6.58e-01 -5.22e-02 8.21e-01
Elevation of cytosolic Ca2+ levels 12 6.59e-01 7.35e-02 8.21e-01
Cyclin D associated events in G1 47 6.60e-01 -3.71e-02 8.21e-01
G1 Phase 47 6.60e-01 -3.71e-02 8.21e-01
Josephin domain DUBs 10 6.60e-01 8.03e-02 8.21e-01
Post NMDA receptor activation events 48 6.60e-01 -3.67e-02 8.21e-01
Transcriptional activation of mitochondrial biogenesis 51 6.61e-01 -3.55e-02 8.21e-01
CRMPs in Sema3A signaling 14 6.68e-01 6.63e-02 8.29e-01
Competing endogenous RNAs (ceRNAs) regulate PTEN translation 11 6.71e-01 7.40e-02 8.31e-01
Blood group systems biosynthesis 17 6.72e-01 -5.92e-02 8.31e-01
Fcgamma receptor (FCGR) dependent phagocytosis 147 6.75e-01 -2.00e-02 8.31e-01
Negative regulation of MAPK pathway 42 6.75e-01 3.73e-02 8.31e-01
Activation of HOX genes during differentiation 68 6.76e-01 2.93e-02 8.31e-01
Activation of anterior HOX genes in hindbrain development during early embryogenesis 68 6.76e-01 2.93e-02 8.31e-01
HIV Transcription Initiation 45 6.77e-01 -3.59e-02 8.31e-01
RNA Polymerase II HIV Promoter Escape 45 6.77e-01 -3.59e-02 8.31e-01
RNA Polymerase II Promoter Escape 45 6.77e-01 -3.59e-02 8.31e-01
RNA Polymerase II Transcription Initiation 45 6.77e-01 -3.59e-02 8.31e-01
RNA Polymerase II Transcription Initiation And Promoter Clearance 45 6.77e-01 -3.59e-02 8.31e-01
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 45 6.77e-01 -3.59e-02 8.31e-01
Nef mediated downregulation of MHC class I complex cell surface expression 10 6.79e-01 -7.55e-02 8.33e-01
Cyclin E associated events during G1/S transition 83 6.80e-01 -2.62e-02 8.34e-01
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 18 6.81e-01 -5.60e-02 8.34e-01
Deubiquitination 241 6.83e-01 1.53e-02 8.36e-01
Signaling by FGFR3 31 6.85e-01 4.21e-02 8.37e-01
Synthesis of glycosylphosphatidylinositol (GPI) 17 6.85e-01 -5.68e-02 8.37e-01
Cell-cell junction organization 38 6.89e-01 -3.75e-02 8.41e-01
SHC-mediated cascade:FGFR1 12 6.93e-01 6.59e-02 8.44e-01
Cell-Cell communication 87 6.93e-01 -2.45e-02 8.44e-01
RUNX3 regulates p14-ARF 10 6.96e-01 7.14e-02 8.47e-01
FRS-mediated FGFR3 signaling 11 6.97e-01 -6.78e-02 8.48e-01
Metabolism of folate and pterines 16 6.99e-01 5.59e-02 8.49e-01
MECP2 regulates neuronal receptors and channels 13 7.04e-01 -6.08e-02 8.55e-01
Signaling by ERBB4 44 7.05e-01 3.30e-02 8.55e-01
MAP3K8 (TPL2)-dependent MAPK1/3 activation 16 7.09e-01 5.40e-02 8.57e-01
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 23 7.09e-01 -4.50e-02 8.57e-01
Platelet Adhesion to exposed collagen 13 7.09e-01 -5.98e-02 8.57e-01
Activation of the AP-1 family of transcription factors 10 7.10e-01 6.78e-02 8.58e-01
PI3K/AKT Signaling in Cancer 80 7.10e-01 -2.40e-02 8.58e-01
GRB2 events in EGFR signaling 11 7.12e-01 6.44e-02 8.58e-01
Downstream signaling events of B Cell Receptor (BCR) 79 7.15e-01 2.38e-02 8.61e-01
MASTL Facilitates Mitotic Progression 10 7.19e-01 -6.57e-02 8.64e-01
Acyl chain remodelling of PG 11 7.19e-01 6.26e-02 8.64e-01
Amino acid transport across the plasma membrane 23 7.19e-01 4.33e-02 8.64e-01
Insulin processing 21 7.20e-01 4.52e-02 8.64e-01
Zinc transporters 14 7.24e-01 5.44e-02 8.69e-01
RNA Polymerase II Pre-transcription Events 78 7.28e-01 -2.28e-02 8.73e-01
Ion homeostasis 40 7.32e-01 3.13e-02 8.76e-01
Signaling by PDGFRA extracellular domain mutants 12 7.33e-01 5.69e-02 8.76e-01
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants 12 7.33e-01 5.69e-02 8.76e-01
SHC1 events in ERBB2 signaling 17 7.33e-01 4.78e-02 8.76e-01
Laminin interactions 21 7.34e-01 4.29e-02 8.76e-01
Other interleukin signaling 18 7.35e-01 4.61e-02 8.76e-01
Formation of Fibrin Clot (Clotting Cascade) 26 7.36e-01 3.82e-02 8.77e-01
ECM proteoglycans 35 7.37e-01 3.28e-02 8.77e-01
Cytosolic iron-sulfur cluster assembly 13 7.39e-01 -5.34e-02 8.79e-01
SIRT1 negatively regulates rRNA expression 24 7.40e-01 -3.91e-02 8.79e-01
Transcriptional Regulation by VENTX 38 7.41e-01 -3.10e-02 8.79e-01
Regulation of PTEN mRNA translation 13 7.42e-01 5.28e-02 8.79e-01
Mitochondrial Fatty Acid Beta-Oxidation 36 7.47e-01 3.11e-02 8.79e-01
CaM pathway 27 7.47e-01 3.59e-02 8.79e-01
Calmodulin induced events 27 7.47e-01 3.59e-02 8.79e-01
Misspliced GSK3beta mutants stabilize beta-catenin 15 7.47e-01 4.81e-02 8.79e-01
S33 mutants of beta-catenin aren’t phosphorylated 15 7.47e-01 4.81e-02 8.79e-01
S37 mutants of beta-catenin aren’t phosphorylated 15 7.47e-01 4.81e-02 8.79e-01
S45 mutants of beta-catenin aren’t phosphorylated 15 7.47e-01 4.81e-02 8.79e-01
T41 mutants of beta-catenin aren’t phosphorylated 15 7.47e-01 4.81e-02 8.79e-01
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 15 7.47e-01 4.81e-02 8.79e-01
Neurotransmitter release cycle 39 7.50e-01 2.95e-02 8.81e-01
Signaling by NTRK3 (TRKC) 16 7.50e-01 -4.60e-02 8.81e-01
Elastic fibre formation 32 7.52e-01 3.23e-02 8.83e-01
FLT3 Signaling 244 7.53e-01 1.17e-02 8.83e-01
Class B/2 (Secretin family receptors) 56 7.54e-01 2.42e-02 8.84e-01
Insulin receptor signalling cascade 39 7.55e-01 2.89e-02 8.84e-01
Xenobiotics 11 7.56e-01 -5.42e-02 8.84e-01
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation 10 7.58e-01 -5.63e-02 8.86e-01
Transport of inorganic cations/anions and amino acids/oligopeptides 79 7.59e-01 2.00e-02 8.86e-01
Antimicrobial peptides 33 7.62e-01 3.04e-02 8.90e-01
Hedgehog ‘off’ state 92 7.64e-01 1.81e-02 8.91e-01
Translation of structural proteins 28 7.64e-01 3.27e-02 8.91e-01
Transcriptional Regulation by MECP2 47 7.67e-01 2.49e-02 8.93e-01
MET activates PTK2 signaling 15 7.68e-01 -4.40e-02 8.93e-01
DAP12 signaling 28 7.69e-01 -3.20e-02 8.93e-01
Glycogen synthesis 13 7.70e-01 4.69e-02 8.93e-01
TNF signaling 43 7.71e-01 -2.56e-02 8.93e-01
Cleavage of the damaged pyrimidine 29 7.72e-01 -3.11e-02 8.93e-01
Depyrimidination 29 7.72e-01 -3.11e-02 8.93e-01
Recognition and association of DNA glycosylase with site containing an affected pyrimidine 29 7.72e-01 -3.11e-02 8.93e-01
Ub-specific processing proteases 170 7.74e-01 -1.28e-02 8.94e-01
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) 10 7.75e-01 5.23e-02 8.95e-01
G alpha (q) signalling events 131 7.76e-01 1.44e-02 8.96e-01
Nuclear signaling by ERBB4 24 7.80e-01 3.29e-02 9.00e-01
ATF6 (ATF6-alpha) activates chaperones 12 7.82e-01 4.61e-02 9.01e-01
Diseases of glycosylation 108 7.82e-01 1.54e-02 9.01e-01
NF-kB is activated and signals survival 12 7.84e-01 -4.57e-02 9.01e-01
Diseases associated with O-glycosylation of proteins 48 7.84e-01 -2.28e-02 9.01e-01
PKA-mediated phosphorylation of CREB 17 7.86e-01 -3.81e-02 9.02e-01
Depolymerisation of the Nuclear Lamina 15 7.87e-01 -4.03e-02 9.03e-01
Disorders of transmembrane transporters 147 7.87e-01 1.29e-02 9.03e-01
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 18 7.90e-01 -3.62e-02 9.04e-01
Signaling by Ligand-Responsive EGFR Variants in Cancer 18 7.90e-01 -3.62e-02 9.04e-01
Receptor-type tyrosine-protein phosphatases 12 7.91e-01 4.43e-02 9.04e-01
Activation of kainate receptors upon glutamate binding 26 7.91e-01 3.00e-02 9.04e-01
Adrenaline,noradrenaline inhibits insulin secretion 24 7.92e-01 3.11e-02 9.04e-01
PKA activation 15 7.92e-01 3.93e-02 9.04e-01
FRS-mediated FGFR1 signaling 14 7.93e-01 4.04e-02 9.04e-01
Alpha-protein kinase 1 signaling pathway 11 7.95e-01 -4.54e-02 9.04e-01
Negative regulation of FGFR4 signaling 21 7.95e-01 3.28e-02 9.04e-01
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects 17 7.96e-01 -3.62e-02 9.04e-01
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) 17 7.96e-01 -3.62e-02 9.04e-01
GPCR ligand binding 229 7.96e-01 -9.91e-03 9.04e-01
Regulation of pyruvate dehydrogenase (PDH) complex 15 8.00e-01 -3.78e-02 9.07e-01
Cholesterol biosynthesis 24 8.01e-01 2.97e-02 9.07e-01
Regulation of RUNX1 Expression and Activity 18 8.02e-01 -3.42e-02 9.07e-01
Nicotinamide salvaging 14 8.02e-01 3.87e-02 9.07e-01
Negative regulation of the PI3K/AKT network 87 8.03e-01 -1.55e-02 9.07e-01
Signalling to RAS 19 8.07e-01 3.23e-02 9.07e-01
RIPK1-mediated regulated necrosis 29 8.08e-01 2.61e-02 9.07e-01
Regulated Necrosis 29 8.08e-01 2.61e-02 9.07e-01
Regulation of necroptotic cell death 29 8.08e-01 2.61e-02 9.07e-01
Heme biosynthesis 14 8.08e-01 3.75e-02 9.07e-01
Sulfur amino acid metabolism 23 8.08e-01 2.93e-02 9.07e-01
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 18 8.08e-01 3.31e-02 9.07e-01
HCMV Late Events 69 8.09e-01 -1.68e-02 9.07e-01
Signaling by ERBB2 44 8.10e-01 -2.09e-02 9.07e-01
Signaling by Nuclear Receptors 218 8.11e-01 -9.41e-03 9.07e-01
Glutathione synthesis and recycling 10 8.11e-01 4.36e-02 9.07e-01
Formation of HIV-1 elongation complex containing HIV-1 Tat 42 8.12e-01 -2.12e-02 9.07e-01
HIV Transcription Elongation 42 8.12e-01 -2.12e-02 9.07e-01
Tat-mediated elongation of the HIV-1 transcript 42 8.12e-01 -2.12e-02 9.07e-01
Diseases associated with N-glycosylation of proteins 17 8.13e-01 -3.31e-02 9.08e-01
Synthesis of very long-chain fatty acyl-CoAs 21 8.16e-01 2.93e-02 9.10e-01
cGMP effects 12 8.17e-01 3.86e-02 9.10e-01
Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71 8.17e-01 1.58e-02 9.10e-01
Base-Excision Repair, AP Site Formation 31 8.19e-01 -2.38e-02 9.10e-01
Abortive elongation of HIV-1 transcript in the absence of Tat 23 8.19e-01 2.75e-02 9.10e-01
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function 53 8.19e-01 1.81e-02 9.10e-01
Signaling by WNT in cancer 30 8.22e-01 2.37e-02 9.12e-01
Cell junction organization 59 8.23e-01 -1.68e-02 9.13e-01
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72 8.27e-01 1.49e-02 9.17e-01
Initiation of Nuclear Envelope (NE) Reformation 19 8.28e-01 2.88e-02 9.17e-01
Signaling by NTRK2 (TRKB) 20 8.30e-01 -2.77e-02 9.18e-01
Signaling by FGFR 69 8.33e-01 -1.47e-02 9.20e-01
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75 8.35e-01 1.39e-02 9.22e-01
Pyruvate metabolism 28 8.39e-01 2.22e-02 9.26e-01
Regulation of MECP2 expression and activity 28 8.39e-01 2.21e-02 9.26e-01
TICAM1-dependent activation of IRF3/IRF7 12 8.43e-01 3.30e-02 9.28e-01
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein 73 8.43e-01 1.34e-02 9.28e-01
Maturation of nucleoprotein 10 8.44e-01 3.60e-02 9.28e-01
MAPK1/MAPK3 signaling 235 8.45e-01 7.39e-03 9.28e-01
Circadian Clock 67 8.48e-01 -1.35e-02 9.28e-01
Interleukin-4 and Interleukin-13 signaling 92 8.49e-01 1.15e-02 9.28e-01
Disorders of Developmental Biology 12 8.49e-01 3.18e-02 9.28e-01
Disorders of Nervous System Development 12 8.49e-01 3.18e-02 9.28e-01
Loss of function of MECP2 in Rett syndrome 12 8.49e-01 3.18e-02 9.28e-01
Pervasive developmental disorders 12 8.49e-01 3.18e-02 9.28e-01
Constitutive Signaling by EGFRvIII 14 8.50e-01 2.92e-02 9.28e-01
Signaling by EGFRvIII in Cancer 14 8.50e-01 2.92e-02 9.28e-01
Peptide ligand-binding receptors 92 8.54e-01 1.11e-02 9.32e-01
FOXO-mediated transcription 58 8.55e-01 -1.38e-02 9.33e-01
Mitochondrial iron-sulfur cluster biogenesis 13 8.57e-01 -2.88e-02 9.34e-01
DAG and IP3 signaling 33 8.60e-01 1.78e-02 9.35e-01
Protein-protein interactions at synapses 57 8.60e-01 1.35e-02 9.35e-01
Biosynthesis of DHA-derived SPMs 14 8.61e-01 -2.71e-02 9.35e-01
HIV elongation arrest and recovery 32 8.61e-01 1.78e-02 9.35e-01
Pausing and recovery of HIV elongation 32 8.61e-01 1.78e-02 9.35e-01
APC/C:Cdc20 mediated degradation of mitotic proteins 74 8.63e-01 1.16e-02 9.35e-01
Protein ubiquitination 72 8.64e-01 -1.17e-02 9.35e-01
Formation of HIV elongation complex in the absence of HIV Tat 44 8.64e-01 -1.50e-02 9.35e-01
MAPK family signaling cascades 269 8.64e-01 6.05e-03 9.35e-01
Glycolysis 67 8.65e-01 1.20e-02 9.35e-01
Purine salvage 12 8.68e-01 2.77e-02 9.36e-01
Keratan sulfate biosynthesis 22 8.69e-01 -2.03e-02 9.36e-01
RNA Pol II CTD phosphorylation and interaction with CE 27 8.69e-01 -1.83e-02 9.36e-01
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 27 8.69e-01 -1.83e-02 9.36e-01
G alpha (i) signalling events 243 8.70e-01 6.10e-03 9.37e-01
Chondroitin sulfate/dermatan sulfate metabolism 38 8.71e-01 -1.52e-02 9.37e-01
Prostacyclin signalling through prostacyclin receptor 16 8.73e-01 2.31e-02 9.38e-01
Transcriptional regulation of pluripotent stem cells 19 8.74e-01 2.10e-02 9.39e-01
Interleukin-7 signaling 21 8.76e-01 -1.96e-02 9.41e-01
RAF/MAP kinase cascade 230 8.78e-01 5.88e-03 9.41e-01
Downstream signal transduction 27 8.81e-01 1.67e-02 9.44e-01
HS-GAG biosynthesis 20 8.83e-01 1.90e-02 9.45e-01
Regulation of FOXO transcriptional activity by acetylation 10 8.84e-01 2.66e-02 9.45e-01
Constitutive Signaling by NOTCH1 HD Domain Mutants 14 8.84e-01 -2.25e-02 9.45e-01
Signaling by NOTCH1 HD Domain Mutants in Cancer 14 8.84e-01 -2.25e-02 9.45e-01
Visual phototransduction 59 8.86e-01 1.07e-02 9.46e-01
ERBB2 Regulates Cell Motility 10 8.89e-01 -2.56e-02 9.48e-01
DDX58/IFIH1-mediated induction of interferon-alpha/beta 63 8.93e-01 9.77e-03 9.51e-01
Formation of the Early Elongation Complex 33 8.94e-01 1.34e-02 9.51e-01
Formation of the HIV-1 Early Elongation Complex 33 8.94e-01 1.34e-02 9.51e-01
NGF-stimulated transcription 31 8.98e-01 1.33e-02 9.54e-01
Ephrin signaling 17 9.01e-01 -1.75e-02 9.57e-01
Acyl chain remodelling of PS 14 9.03e-01 -1.89e-02 9.57e-01
Packaging Of Telomere Ends 20 9.04e-01 1.56e-02 9.57e-01
Lewis blood group biosynthesis 13 9.05e-01 -1.91e-02 9.57e-01
Formation of the beta-catenin:TCF transactivating complex 46 9.05e-01 -1.01e-02 9.57e-01
ATF6 (ATF6-alpha) activates chaperone genes 10 9.06e-01 2.16e-02 9.57e-01
PECAM1 interactions 12 9.06e-01 1.97e-02 9.57e-01
Signaling by FGFR4 31 9.06e-01 1.22e-02 9.57e-01
Signaling by EGFR in Cancer 23 9.06e-01 -1.41e-02 9.57e-01
NRIF signals cell death from the nucleus 15 9.08e-01 1.72e-02 9.58e-01
Regulation of localization of FOXO transcription factors 11 9.11e-01 1.95e-02 9.59e-01
Potential therapeutics for SARS 77 9.12e-01 -7.32e-03 9.59e-01
Interferon gamma signaling 83 9.13e-01 6.96e-03 9.59e-01
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13 9.13e-01 -1.74e-02 9.59e-01
Cristae formation 31 9.14e-01 1.13e-02 9.59e-01
Pexophagy 11 9.14e-01 1.89e-02 9.59e-01
Pausing and recovery of Tat-mediated HIV elongation 30 9.15e-01 1.12e-02 9.60e-01
Tat-mediated HIV elongation arrest and recovery 30 9.15e-01 1.12e-02 9.60e-01
STING mediated induction of host immune responses 15 9.17e-01 -1.55e-02 9.60e-01
Cell-extracellular matrix interactions 14 9.17e-01 1.60e-02 9.60e-01
Peptide hormone metabolism 51 9.18e-01 -8.38e-03 9.60e-01
Synthesis of active ubiquitin: roles of E1 and E2 enzymes 30 9.19e-01 -1.08e-02 9.60e-01
IL-6-type cytokine receptor ligand interactions 12 9.24e-01 -1.59e-02 9.65e-01
p75NTR recruits signalling complexes 12 9.25e-01 1.57e-02 9.65e-01
Negative regulation of FGFR2 signaling 23 9.27e-01 -1.11e-02 9.66e-01
Nitric oxide stimulates guanylate cyclase 15 9.27e-01 -1.37e-02 9.66e-01
Leishmania infection 245 9.28e-01 -3.34e-03 9.67e-01
Receptor Mediated Mitophagy 11 9.30e-01 1.52e-02 9.68e-01
Mitochondrial biogenesis 88 9.32e-01 -5.28e-03 9.68e-01
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 21 9.32e-01 1.07e-02 9.68e-01
Intrinsic Pathway for Apoptosis 52 9.33e-01 6.77e-03 9.68e-01
SHC1 events in ERBB4 signaling 10 9.34e-01 -1.51e-02 9.68e-01
Response of EIF2AK1 (HRI) to heme deficiency 14 9.35e-01 1.26e-02 9.68e-01
Signaling by PDGFR in disease 19 9.36e-01 -1.07e-02 9.68e-01
Diseases associated with glycosaminoglycan metabolism 26 9.36e-01 9.15e-03 9.68e-01
Signaling by PDGF 44 9.36e-01 6.99e-03 9.68e-01
Regulation of PTEN gene transcription 59 9.39e-01 -5.74e-03 9.70e-01
O-linked glycosylation 83 9.40e-01 -4.74e-03 9.70e-01
Formation of RNA Pol II elongation complex 57 9.41e-01 5.68e-03 9.70e-01
RNA Polymerase II Transcription Elongation 57 9.41e-01 5.68e-03 9.70e-01
Purine catabolism 16 9.42e-01 1.05e-02 9.71e-01
Ovarian tumor domain proteases 37 9.44e-01 -6.72e-03 9.71e-01
Acyl chain remodelling of PE 20 9.47e-01 8.65e-03 9.74e-01
Intrinsic Pathway of Fibrin Clot Formation 16 9.49e-01 -9.28e-03 9.75e-01
p75NTR signals via NF-kB 15 9.49e-01 -9.51e-03 9.75e-01
Synthesis of PA 32 9.51e-01 -6.22e-03 9.77e-01
TRP channels 17 9.52e-01 8.36e-03 9.77e-01
Ca2+ pathway 57 9.56e-01 -4.25e-03 9.79e-01
Activation of RAC1 11 9.57e-01 9.49e-03 9.80e-01
Downstream signaling of activated FGFR1 20 9.57e-01 6.93e-03 9.80e-01
Constitutive Signaling by Overexpressed ERBB2 11 9.60e-01 -8.78e-03 9.81e-01
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 36 9.60e-01 -4.80e-03 9.81e-01
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 80 9.62e-01 3.07e-03 9.82e-01
TICAM1, RIP1-mediated IKK complex recruitment 19 9.66e-01 5.69e-03 9.85e-01
Interferon alpha/beta signaling 57 9.67e-01 -3.15e-03 9.86e-01
mitochondrial fatty acid beta-oxidation of saturated fatty acids 11 9.69e-01 -6.84e-03 9.87e-01
Neddylation 218 9.69e-01 1.52e-03 9.87e-01
Condensation of Prophase Chromosomes 29 9.70e-01 -3.98e-03 9.87e-01
Interleukin-2 signaling 11 9.75e-01 -5.42e-03 9.87e-01
Unfolded Protein Response (UPR) 86 9.75e-01 1.92e-03 9.87e-01
Inhibition of DNA recombination at telomere 35 9.76e-01 -2.88e-03 9.87e-01
AMER1 mutants destabilize the destruction complex 14 9.79e-01 4.02e-03 9.87e-01
APC truncation mutants have impaired AXIN binding 14 9.79e-01 4.02e-03 9.87e-01
AXIN missense mutants destabilize the destruction complex 14 9.79e-01 4.02e-03 9.87e-01
AXIN mutants destabilize the destruction complex, activating WNT signaling 14 9.79e-01 4.02e-03 9.87e-01
Truncations of AMER1 destabilize the destruction complex 14 9.79e-01 4.02e-03 9.87e-01
truncated APC mutants destabilize the destruction complex 14 9.79e-01 4.02e-03 9.87e-01
Metabolism of water-soluble vitamins and cofactors 109 9.80e-01 -1.42e-03 9.87e-01
Cleavage of the damaged purine 24 9.80e-01 -3.02e-03 9.87e-01
Depurination 24 9.80e-01 -3.02e-03 9.87e-01
Recognition and association of DNA glycosylase with site containing an affected purine 24 9.80e-01 -3.02e-03 9.87e-01
HS-GAG degradation 16 9.82e-01 -3.20e-03 9.88e-01
Signaling by FGFR in disease 50 9.83e-01 1.79e-03 9.88e-01
Transcriptional regulation by RUNX1 184 9.87e-01 -6.87e-04 9.92e-01
E3 ubiquitin ligases ubiquitinate target proteins 52 9.89e-01 -1.06e-03 9.94e-01
RAF-independent MAPK1/3 activation 21 9.92e-01 1.28e-03 9.96e-01
TP53 Regulates Transcription of Cell Death Genes 42 9.93e-01 7.83e-04 9.96e-01
VEGFR2 mediated cell proliferation 18 9.95e-01 8.48e-04 9.97e-01
Assembly of the pre-replicative complex 66 9.96e-01 -3.75e-04 9.97e-01
PI-3K cascade:FGFR1 12 9.99e-01 2.62e-04 9.99e-01
Synthesis of PIPs at the early endosome membrane 16 1.00e+00 -5.78e-05 1.00e+00


Detailed Gene set reports



rRNA processing in the nucleus and cytosol

rRNA processing in the nucleus and cytosol
1355
set rRNA processing in the nucleus and cytosol
setSize 190
pANOVA 6.06e-45
s.dist -0.59
p.adjustANOVA 8.26e-42



Top enriched genes

Top 20 genes
GeneID Gene Rank
DKC1 -9835
TSR1 -9723
NOP14 -9719
RPL3 -9701
FBL -9671
RPS2 -9635
RPP40 -9619
RPL14 -9390
RPL23A -9382
GNL3 -9380
NOP58 -9366
RPL5 -9359
NOL11 -9354
UTP4 -9338
NAT10 -9326
THUMPD1 -9311
RPS3A -9257
NOB1 -9253
DIMT1 -9230
WDR75 -9213

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DKC1 -9835
TSR1 -9723
NOP14 -9719
RPL3 -9701
FBL -9671
RPS2 -9635
RPP40 -9619
RPL14 -9390
RPL23A -9382
GNL3 -9380
NOP58 -9366
RPL5 -9359
NOL11 -9354
UTP4 -9338
NAT10 -9326
THUMPD1 -9311
RPS3A -9257
NOB1 -9253
DIMT1 -9230
WDR75 -9213
RPS6 -9170
NCL -9167
BMS1 -9164
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
WDR43 -8851
RPS25 -8832
RPL21 -8773
TEX10 -8744
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
LAS1L -8501
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RIOK2 -8405
RPS12 -8401
NOP56 -8346
RPS14 -8337
RPS23 -8334
RPL10 -8318
UTP15 -8280
EXOSC5 -8271
RPS27 -8260
RPLP2 -8255
IMP4 -8233
EXOSC2 -8172
RPL36A -8130
NIP7 -8124
RRP9 -8121
RPS7 -8047
RPL35A -8046
RPL10A -7989
SNU13 -7987
EXOSC6 -7982
PDCD11 -7980
WDR3 -7973
DDX47 -7962
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
EXOSC8 -7905
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
RCL1 -7761
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
RPP25 -7624
RPS16 -7617
RPL18A -7609
CSNK1E -7527
RPL31 -7521
PNO1 -7506
EXOSC9 -7477
RPL9 -7451
RPL15 -7380
RPS13 -7375
HEATR1 -7360
PELP1 -7329
RPL7A -7296
RPS18 -7288
PWP2 -7199
NOL9 -7193
RPP30 -7173
RPS8 -7161
RPS17 -7134
RPL19 -7006
IMP3 -6997
WDR46 -6977
NOL6 -6945
RPL23 -6933
UTP20 -6898
EBNA1BP2 -6864
RPS29 -6791
RPS11 -6742
EMG1 -6735
RPS21 -6706
GAR1 -6696
RPL37 -6660
MPHOSPH10 -6590
RPL38 -6589
EXOSC7 -6585
RPP38 -6534
KRR1 -6432
RPS28 -6429
RPL36 -6343
NOP2 -6275
RPL8 -6274
RPL27 -6068
RPL41 -6065
BYSL -5863
WDR36 -5853
RBM28 -5810
RPL39 -5790
DHX37 -5761
NHP2 -5747
RPS19 -5616
RPL13 -5550
RPS26 -5524
PES1 -5491
UTP6 -5444
RPS15 -5342
RPS24 -5310
BOP1 -5141
EXOSC10 -5112
RPL37A -4774
MTREX -4734
LTV1 -4592
RRP7A -4574
RPSA -4559
WDR18 -4348
DCAF13 -4245
RPL36AL -4148
DIS3 -3916
RPLP1 -3887
DDX21 -3746
RIOK1 -3329
UTP14A -3160
FCF1 -3010
RPP14 -2433
MPHOSPH6 -2335
RPL28 -1952
UTP14C -1630
UTP3 -1460
UBA52 -1437
WDR12 -1301
FAU -1029
TRMT112 -370
TSR3 -358
RPP21 -200
RPL39L -69
ISG20L2 -43
TBL3 55
EXOSC3 280
RRP36 511
C1D 531
RRP1 874
UTP11 1268
RPS4Y1 1461
DDX52 1503
ERI1 1991
RPS9 2392
EXOSC1 2569
RIOK3 2755
RPS27L 2784
FTSJ3 3515
UTP18 3740
DDX49 4194
SENP3 4233
RPL3L 5700
NOL12 5766
RPL26L1 6187
CSNK1D 7458
NOC4L 7461
EXOSC4 8895
XRN2 9350
NOP10 10793
SNORD3A 11429


rRNA processing

rRNA processing
1353
set rRNA processing
setSize 217
pANOVA 4.38e-44
s.dist -0.547
p.adjustANOVA 2.99e-41



Top enriched genes

Top 20 genes
GeneID Gene Rank
DKC1 -9835
TSR1 -9723
NOP14 -9719
RPL3 -9701
FBL -9671
RPS2 -9635
RPP40 -9619
MTERF4 -9490
RPL14 -9390
RPL23A -9382
GNL3 -9380
NOP58 -9366
RPL5 -9359
NOL11 -9354
UTP4 -9338
NAT10 -9326
THUMPD1 -9311
RPS3A -9257
NOB1 -9253
DIMT1 -9230

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DKC1 -9835
TSR1 -9723
NOP14 -9719
RPL3 -9701
FBL -9671
RPS2 -9635
RPP40 -9619
MTERF4 -9490
RPL14 -9390
RPL23A -9382
GNL3 -9380
NOP58 -9366
RPL5 -9359
NOL11 -9354
UTP4 -9338
NAT10 -9326
THUMPD1 -9311
RPS3A -9257
NOB1 -9253
DIMT1 -9230
WDR75 -9213
RPS6 -9170
NCL -9167
BMS1 -9164
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
WDR43 -8851
RPS25 -8832
RPL21 -8773
TEX10 -8744
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
LAS1L -8501
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RIOK2 -8405
RPS12 -8401
NOP56 -8346
RPS14 -8337
RPS23 -8334
RPL10 -8318
UTP15 -8280
EXOSC5 -8271
TRMT10C -8270
RPS27 -8260
RPLP2 -8255
IMP4 -8233
EXOSC2 -8172
RPL36A -8130
NIP7 -8124
RRP9 -8121
RPS7 -8047
RPL35A -8046
RPL10A -7989
SNU13 -7987
EXOSC6 -7982
PDCD11 -7980
WDR3 -7973
DDX47 -7962
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
EXOSC8 -7905
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
RCL1 -7761
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
RPP25 -7624
RPS16 -7617
RPL18A -7609
CSNK1E -7527
RPL31 -7521
PNO1 -7506
EXOSC9 -7477
RPL9 -7451
RPL15 -7380
RPS13 -7375
HEATR1 -7360
PELP1 -7329
RPL7A -7296
RPS18 -7288
PWP2 -7199
NOL9 -7193
MRM1 -7180
RPP30 -7173
RPS8 -7161
RPS17 -7134
RPL19 -7006
IMP3 -6997
WDR46 -6977
NOL6 -6945
RPL23 -6933
UTP20 -6898
EBNA1BP2 -6864
RPS29 -6791
RPS11 -6742
EMG1 -6735
MT-ND2 -6727
RPS21 -6706
GAR1 -6696
RPL37 -6660
MPHOSPH10 -6590
RPL38 -6589
EXOSC7 -6585
RPP38 -6534
MT-RNR1 -6484
KRR1 -6432
RPS28 -6429
RPL36 -6343
NOP2 -6275
RPL8 -6274
RPL27 -6068
RPL41 -6065
BYSL -5863
WDR36 -5853
MT-ND1 -5852
RBM28 -5810
RPL39 -5790
DHX37 -5761
NHP2 -5747
RPS19 -5616
RPL13 -5550
RPS26 -5524
MRM3 -5496
PES1 -5491
UTP6 -5444
RPS15 -5342
RPS24 -5310
BOP1 -5141
EXOSC10 -5112
RPL37A -4774
MTREX -4734
TFB1M -4603
LTV1 -4592
RRP7A -4574
RPSA -4559
WDR18 -4348
MT-CO3 -4247
DCAF13 -4245
RPL36AL -4148
DIS3 -3916
RPLP1 -3887
DDX21 -3746
ELAC2 -3686
PRORP -3614
RIOK1 -3329
MRM2 -3190
MT-ND5 -3188
UTP14A -3160
FCF1 -3010
MT-ND3 -2969
RPP14 -2433
MPHOSPH6 -2335
MT-CYB -2095
RPL28 -1952
UTP14C -1630
UTP3 -1460
UBA52 -1437
WDR12 -1301
FAU -1029
TRMT112 -370
TSR3 -358
RPP21 -200
MT-RNR2 -141
RPL39L -69
ISG20L2 -43
MT-ATP6 36
TBL3 55
EXOSC3 280
MT-CO1 507
RRP36 511
C1D 531
MT-CO2 729
RRP1 874
MT-TF 1008
UTP11 1268
RPS4Y1 1461
DDX52 1503
MT-ATP8 1944
ERI1 1991
RPS9 2392
EXOSC1 2569
RIOK3 2755
RPS27L 2784
MT-ND4L 3155
FTSJ3 3515
UTP18 3740
NSUN4 4135
DDX49 4194
SENP3 4233
MT-TV 4515
MT-TL1 5025
RPL3L 5700
NOL12 5766
MT-ND4 5850
RPL26L1 6187
HSD17B10 6466
CSNK1D 7458
NOC4L 7461
EXOSC4 8895
XRN2 9350
NOP10 10793
SNORD3A 11429


Neutrophil degranulation

Neutrophil degranulation
735
set Neutrophil degranulation
setSize 457
pANOVA 3.04e-43
s.dist 0.376
p.adjustANOVA 1.16e-40



Top enriched genes

Top 20 genes
GeneID Gene Rank
LILRB2 11743
SLC11A1 11742
P2RX1 11737
OSCAR 11726
DOK3 11717
NCSTN 11715
TCIRG1 11708
HK3 11695
DNASE1L1 11691
SERPINA1 11685
ANPEP 11677
C3AR1 11629
FGR 11610
SIRPA 11601
GNS 11592
ITGAX 11581
ACAA1 11576
HP 11572
IDH1 11571
CD63 11550

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
LILRB2 11743
SLC11A1 11742
P2RX1 11737
OSCAR 11726
DOK3 11717
NCSTN 11715
TCIRG1 11708
HK3 11695
DNASE1L1 11691
SERPINA1 11685
ANPEP 11677
C3AR1 11629
FGR 11610
SIRPA 11601
GNS 11592
ITGAX 11581
ACAA1 11576
HP 11572
IDH1 11571
CD63 11550
QSOX1 11547
RNASE2 11535
PRKCD 11506
FCER1G 11505
SIGLEC9 11493
MOSPD2 11479
LAIR1 11472
ATP6V0A1 11467
CTSD 11452
CTSB 11445
CR1 11436
GUSB 11435
S100A9 11432
ASAH1 11411
NEU1 11402
NCKAP1L 11401
AGPAT2 11396
CD36 11354
TNFAIP6 11338
IMPDH1 11335
VNN1 11333
ALDH3B1 11330
FPR1 11322
TIMP2 11318
S100A8 11315
PECAM1 11314
MCEMP1 11306
PGAM1 11305
ITGAM 11288
BRI3 11285
PLAC8 11276
UNC13D 11268
PTPN6 11254
GM2A 11237
NFAM1 11188
CDA 11180
ANXA2 11174
TRPM2 11170
ALOX5 11153
CYFIP1 11117
C5AR1 11109
CD177 11101
PYCARD 11094
GRN 11084
S100A11 11078
S100A12 11077
GLA 11064
LTA4H 11060
CRISPLD2 11052
VAT1 11042
TNFRSF1B 11022
COTL1 11009
CD68 10980
PLEKHO2 10971
ITGB2 10970
ALDOA 10937
SERPINB1 10935
CSTB 10924
TOM1 10915
RAC1 10907
RAB10 10903
PADI2 10877
PSEN1 10871
ATP6V0C 10858
MAPK1 10847
GLB1 10846
PLAUR 10834
CD93 10813
FPR2 10794
PYGL 10789
ATP11A 10784
CTSZ 10773
TLR2 10761
PTAFR 10758
TYROBP 10755
GCA 10753
CD55 10741
NBEAL2 10699
ARHGAP9 10674
CD300A 10650
MMP25 10645
NAPRT 10642
RHOG 10634
CYBA 10617
RAB24 10600
TSPAN14 10591
PKM 10547
LILRB3 10546
CD14 10542
PLD1 10520
RETN 10519
CTSA 10517
CEACAM3 10514
CPPED1 10512
MAPK14 10466
ALAD 10444
ADGRG3 10443
AP2A2 10434
BIN2 10421
QPCT 10407
ARSB 10406
STK11IP 10391
FCGR2A 10355
FTL 10348
MMP9 10322
GYG1 10290
HPSE 10288
BST1 10273
CD53 10254
CAPN1 10238
DOCK2 10229
RAB4B 10224
RAB5C 10197
CYBB 10196
GPR84 10194
RAB3D 10172
AP1M1 10145
CKAP4 10088
IGF2R 10077
MGST1 10069
ARPC5 10048
CD58 10047
RAB31 10045
PSAP 10019
CFP 9950
HSPA6 9912
DNAJC5 9897
GSN 9887
LAMTOR1 9855
CYB5R3 9808
MGAM 9760
GALNS 9756
SLC2A3 9751
PDAP1 9730
ATP6V1D 9706
SLC15A4 9689
CLEC4D 9682
ADGRE5 9681
DERA 9675
ACLY 9642
DNAJC13 9641
ARSA 9608
DBNL 9555
GMFG 9547
PGM2 9542
SDCBP 9536
LRG1 9534
CTSC 9524
CYSTM1 9471
S100P 9448
PTPRJ 9428
CAT 9425
AMPD3 9412
CD33 9340
MNDA 9331
FOLR3 9323
LAMTOR2 9311
RAB7A 9295
LGALS3 9294
TMBIM1 9252
ARL8A 9235
SERPINB6 9209
FCN1 9194
VPS35L 9180
MVP 9155
ADAM10 9130
ARG1 9013
FCAR 9011
COMMD9 9004
IQGAP1 8998
IQGAP2 8896
TRAPPC1 8880
SELL 8826
RNASET2 8806
RHOA 8752
PSMD6 8745
LAMP1 8606
PNP 8604
SNAP29 8589
CD44 8470
CAP1 8422
DNAJC3 8291
GAA 8265
VAPA 8135
ITGAV 8115
MANBA 8050
PSMB7 7941
RAB27A 7933
DYNC1LI1 7881
CREG1 7822
TOLLIP 7802
CANT1 7672
CMTM6 7664
PDXK 7660
IST1 7650
RAB6A 7579
PRCP 7572
NPC2 7560
PTPRC 7546
DYNLT1 7489
DDOST 7465
METTL7A 7399
KCNAB2 7393
LAMP2 7357
ACTR2 7352
STK10 7292
CTSS 7190
PSMD11 7057
NHLRC3 7045
SIRPB1 7036
RAP1A 7021
ROCK1 7020
HEXB 6925
NDUFC2 6785
CTSH 6758
MAN2B1 6709
HSPA1A 6708
OSTF1 6599
TUBB4B 6583
CSNK2B 6563
YPEL5 6553
PIGR 6544
FUCA2 6509
FUCA1 6504
NFASC 6488
FABP5 6480
FTH1 6366
PSMD1 6354
SIGLEC5 6250
COPB1 6181
ATG7 6077
APAF1 6024
CXCR1 6006
ADAM8 5994
PRDX4 5952
CAB39 5909
GLIPR1 5779
CLEC5A 5765
PSMD12 5714
HEBP2 5680
TICAM2 5572
PSMD2 5544
DGAT1 5440
RAP1B 5363
GDI2 5257
LPCAT1 5222
SURF4 5135
CNN2 5113
B4GALT1 5109
RAP2C 5053
SRP14 5005
RAB5B 4935
PGM1 4743
GPI 4667
TARM1 4634
ATP11B 4630
ORM2 4551
TMEM30A 4528
PSMC2 4457
APEH 4454
HSPA1B 4429
RAB18 4366
SNAP23 4343
CEACAM1 4318
GSDMD 4284
VCP 4271
VAMP8 4250
FRK 4243
ACTR10 4228
PSMD3 4177
FAF2 4132
KCMF1 4047
SERPINB10 3849
HVCN1 3781
PSMD13 3770
CST3 3572
ORM1 3469
STOM 3437
DYNLL1 3185
GHDC 3169
HLA-C 3114
CLEC4C 3103
SLCO4C1 3100
ERP44 2957
RAB14 2942
ITGAL 2879
UBR4 2841
GGH 2692
DSP 2606
CLEC12A 2566
PLAU 2369
DIAPH1 2357
PAFAH1B2 2356
HLA-B 2308
CFD 2249
PSMC3 2182
LAMTOR3 2053
PGLYRP1 1994
ATP6AP2 1907
C3 1898
NRAS 1826
GSTP1 1776
COMMD3 1730
ATP8B4 1600
PSMD7 1547
CXCR2 1488
A1BG 1362
RAB3A 1226
VCL 1210
PFKL 1186
RNASE3 1013
RAP2B 1004
TMEM179B 986
BST2 980
C6orf120 822
MMP8 336
PSMD14 225
ARMC8 184
SIGLEC14 129
MAGT1 71
CXCL1 35
SLC44A2 34
CDK13 32
OLFM4 -31
ANO6 -52
HBB -79
KPNB1 -109
CPNE3 -215
CCT8 -260
DEGS1 -381
NME2 -399
STBD1 -458
STING1 -472
LRRC7 -743
LYZ -787
PRDX6 -823
SLPI -957
PTX3 -1006
DYNC1H1 -1040
CPNE1 -1135
ADGRE3 -1159
HLA-H -1311
DEFA1 -1338
CRACR2A -1363
DDX3X -1650
HUWE1 -1658
MME -1743
PTPRB -1899
EPX -1916
PSMB1 -1960
PSMA2 -2032
JUP -2056
SYNGR1 -2163
NFKB1 -2166
AGL -2364
PTPRN2 -2372
XRCC5 -2484
FCGR3B -2630
CHIT1 -2666
PYGB -3068
SLC2A5 -3147
CD59 -3215
DEFA4 -3234
PTGES2 -3328
DSN1 -3386
HRNR -3513
HGSNAT -3596
MLEC -3628
AOC1 -3663
PGRMC1 -3760
FGL2 -4013
ILF2 -4055
DPP7 -4153
TXNDC5 -4205
PPIA -4561
RAB9B -4668
TMC6 -4698
GOLGA7 -4761
LCN2 -4914
ACTR1B -5027
PPIE -5064
HSP90AA1 -5083
CEACAM6 -5119
ENPP4 -5217
TUBB -5289
HLA-A -5456
CRISP3 -5472
PA2G4 -5544
CHI3L1 -5551
CTSG -5681
PPBP -5719
RAB44 -5839
AGA -5943
MS4A3 -5983
ELANE -6034
ABCA13 -6063
ALDOC -6087
OLR1 -6122
ATAD3B -6192
CEP290 -6203
TCN1 -6219
RAB37 -6287
APRT -6333
PSMA5 -6362
PRTN3 -6370
CEACAM8 -6488
LTF -6540
MIF -6822
FRMPD3 -7031
EEF2 -7073
BPI -7115
CAND1 -7207
AZU1 -7221
TBC1D10C -7271
SLC27A2 -7272
KRT1 -7308
B2M -7346
TMEM63A -7364
SVIP -7384
NIT2 -7632
CAMP -7637
SCAMP1 -7668
HMGB1 -7684
XRCC6 -7770
MPO -7958
ORMDL3 -8162
CD47 -8257
RHOF -9031
HSP90AB1 -9152
HSPA8 -9166
HMOX2 -9212
DSC1 -9305
EEF1A1 -9389
ATP8A1 -9501
SPTAN1 -9516
CCT2 -9661
IMPDH2 -9848


Major pathway of rRNA processing in the nucleolus and cytosol

Major pathway of rRNA processing in the nucleolus and cytosol
625
set Major pathway of rRNA processing in the nucleolus and cytosol
setSize 180
pANOVA 3.41e-43
s.dist -0.594
p.adjustANOVA 1.16e-40



Top enriched genes

Top 20 genes
GeneID Gene Rank
TSR1 -9723
NOP14 -9719
RPL3 -9701
FBL -9671
RPS2 -9635
RPP40 -9619
RPL14 -9390
RPL23A -9382
GNL3 -9380
NOP58 -9366
RPL5 -9359
NOL11 -9354
UTP4 -9338
RPS3A -9257
NOB1 -9253
WDR75 -9213
RPS6 -9170
NCL -9167
BMS1 -9164
RPL7 -9134

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TSR1 -9723
NOP14 -9719
RPL3 -9701
FBL -9671
RPS2 -9635
RPP40 -9619
RPL14 -9390
RPL23A -9382
GNL3 -9380
NOP58 -9366
RPL5 -9359
NOL11 -9354
UTP4 -9338
RPS3A -9257
NOB1 -9253
WDR75 -9213
RPS6 -9170
NCL -9167
BMS1 -9164
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
WDR43 -8851
RPS25 -8832
RPL21 -8773
TEX10 -8744
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
LAS1L -8501
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RIOK2 -8405
RPS12 -8401
NOP56 -8346
RPS14 -8337
RPS23 -8334
RPL10 -8318
UTP15 -8280
EXOSC5 -8271
RPS27 -8260
RPLP2 -8255
IMP4 -8233
EXOSC2 -8172
RPL36A -8130
NIP7 -8124
RRP9 -8121
RPS7 -8047
RPL35A -8046
RPL10A -7989
SNU13 -7987
EXOSC6 -7982
PDCD11 -7980
WDR3 -7973
DDX47 -7962
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
EXOSC8 -7905
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
RCL1 -7761
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
RPP25 -7624
RPS16 -7617
RPL18A -7609
CSNK1E -7527
RPL31 -7521
PNO1 -7506
EXOSC9 -7477
RPL9 -7451
RPL15 -7380
RPS13 -7375
HEATR1 -7360
PELP1 -7329
RPL7A -7296
RPS18 -7288
PWP2 -7199
NOL9 -7193
RPP30 -7173
RPS8 -7161
RPS17 -7134
RPL19 -7006
IMP3 -6997
WDR46 -6977
NOL6 -6945
RPL23 -6933
UTP20 -6898
EBNA1BP2 -6864
RPS29 -6791
RPS11 -6742
EMG1 -6735
RPS21 -6706
RPL37 -6660
MPHOSPH10 -6590
RPL38 -6589
EXOSC7 -6585
RPP38 -6534
KRR1 -6432
RPS28 -6429
RPL36 -6343
RPL8 -6274
RPL27 -6068
RPL41 -6065
BYSL -5863
WDR36 -5853
RBM28 -5810
RPL39 -5790
DHX37 -5761
RPS19 -5616
RPL13 -5550
RPS26 -5524
PES1 -5491
UTP6 -5444
RPS15 -5342
RPS24 -5310
BOP1 -5141
EXOSC10 -5112
RPL37A -4774
MTREX -4734
LTV1 -4592
RRP7A -4574
RPSA -4559
WDR18 -4348
DCAF13 -4245
RPL36AL -4148
DIS3 -3916
RPLP1 -3887
DDX21 -3746
RIOK1 -3329
UTP14A -3160
FCF1 -3010
RPP14 -2433
MPHOSPH6 -2335
RPL28 -1952
UTP14C -1630
UTP3 -1460
UBA52 -1437
WDR12 -1301
FAU -1029
RPP21 -200
RPL39L -69
ISG20L2 -43
TBL3 55
EXOSC3 280
RRP36 511
C1D 531
RRP1 874
UTP11 1268
RPS4Y1 1461
DDX52 1503
ERI1 1991
RPS9 2392
EXOSC1 2569
RIOK3 2755
RPS27L 2784
FTSJ3 3515
UTP18 3740
DDX49 4194
SENP3 4233
RPL3L 5700
NOL12 5766
RPL26L1 6187
CSNK1D 7458
NOC4L 7461
EXOSC4 8895
XRN2 9350
SNORD3A 11429


Metabolism of RNA

Metabolism of RNA
635
set Metabolism of RNA
setSize 685
pANOVA 1.57e-38
s.dist -0.29
p.adjustANOVA 4.27e-36



Top enriched genes

Top 20 genes
GeneID Gene Rank
DKC1 -9835
NDC1 -9817
THOC3 -9796
GEMIN4 -9746
TSR1 -9723
NOP14 -9719
RPL3 -9701
MT-TP -9673
FBL -9671
RPS2 -9635
NUP35 -9626
RPP40 -9619
ALKBH8 -9608
MTERF4 -9490
LSM11 -9482
NUP88 -9430
MYC -9418
RPL14 -9390
RPL23A -9382
GNL3 -9380

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DKC1 -9835
NDC1 -9817
THOC3 -9796
GEMIN4 -9746
TSR1 -9723
NOP14 -9719
RPL3 -9701
MT-TP -9673
FBL -9671
RPS2 -9635
NUP35 -9626
RPP40 -9619
ALKBH8 -9608
MTERF4 -9490
LSM11 -9482
NUP88 -9430
MYC -9418
RPL14 -9390
RPL23A -9382
GNL3 -9380
NOP58 -9366
RPL5 -9359
EIF4A2 -9355
NOL11 -9354
UTP4 -9338
NAT10 -9326
RBMX -9321
THUMPD1 -9311
RPS3A -9257
NOB1 -9253
DIMT1 -9230
WDR75 -9213
RPS6 -9170
NCL -9167
HSPA8 -9166
BMS1 -9164
DCP1B -9162
RPL7 -9134
CNOT6L -9114
TRMT11 -9107
DDX20 -9102
TYW1 -9075
RPL4 -9065
HNRNPA0 -9015
GCFC2 -8941
RPL22 -8915
METTL1 -8884
PUS7 -8881
RPS3 -8856
WDR43 -8851
SNRPN -8838
RPS25 -8832
TP53RK -8827
NUP107 -8801
SEH1L -8792
SF3B3 -8790
RPL21 -8773
TEX10 -8744
RPS27A -8722
ZNF473 -8717
NUP160 -8699
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
WBP11 -8686
NUDT21 -8636
PHAX -8612
CNOT7 -8609
NXT1 -8554
PRPF19 -8548
LAS1L -8501
RPL6 -8498
SNRNP40 -8492
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RIOK2 -8405
RPS12 -8401
NOP56 -8346
RPS14 -8337
GSPT2 -8336
RPS23 -8334
EIF4B -8328
RPL10 -8318
UTP15 -8280
EXOSC5 -8271
TRMT10C -8270
RPS27 -8260
RPLP2 -8255
IMP4 -8233
NCBP2 -8212
EXOSC2 -8172
POLR2D -8160
RPL36A -8130
NIP7 -8124
RRP9 -8121
LSM5 -8094
TSEN54 -8093
RPS7 -8047
RPL35A -8046
SRSF5 -7996
RPL10A -7989
SNU13 -7987
EXOSC6 -7982
PDCD11 -7980
WDR3 -7973
GTF2H3 -7969
DDX47 -7962
RPL29 -7954
SET -7950
RPL11 -7928
RPL32 -7914
RPS15A -7912
EXOSC8 -7905
HNRNPR -7882
SRSF11 -7838
UPF3A -7835
RPL22L1 -7828
TYW3 -7825
NUP43 -7792
RPL30 -7783
RPL18 -7781
RCL1 -7761
SRSF10 -7755
PPIH -7717
RPL35 -7710
TRMT61B -7694
RPL26 -7648
RPS4X -7636
NUP155 -7633
RPS10 -7629
RPL24 -7626
PSMB9 -7625
RPP25 -7624
RPS16 -7617
RPL18A -7609
RAN -7577
CSNK1E -7527
RPL31 -7521
LCMT2 -7516
PNO1 -7506
FYTTD1 -7487
EXOSC9 -7477
HNRNPA1 -7469
RPL9 -7451
QTRT1 -7397
RPL15 -7380
CSTF1 -7377
RPS13 -7375
HEATR1 -7360
DCP1A -7356
PELP1 -7329
GEMIN5 -7299
RPL7A -7296
NUP188 -7295
RPS18 -7288
HNRNPA3 -7261
TNKS1BP1 -7235
TRMT13 -7202
PWP2 -7199
NOL9 -7193
GTF2H1 -7185
MRM1 -7180
RPP30 -7173
PPIL1 -7166
RPS8 -7161
TPRKB -7143
RPS17 -7134
PRPF6 -7127
SRSF6 -7099
TSEN15 -7067
TSEN2 -7057
NUP205 -7051
RNPS1 -7032
TRMT61A -7025
RPL19 -7006
IMP3 -6997
SNRPE -6979
WDR46 -6977
WDR77 -6973
NOL6 -6945
TTC37 -6940
RPL23 -6933
UTP20 -6898
EBNA1BP2 -6864
SF3A3 -6863
EPRS1 -6849
RPS29 -6791
PLRG1 -6780
RPS11 -6742
EMG1 -6735
MT-ND2 -6727
SNRPF -6725
RPS21 -6706
GAR1 -6696
RPL37 -6660
MPHOSPH10 -6590
RPL38 -6589
EXOSC7 -6585
GSPT1 -6576
RPP38 -6534
MT-RNR1 -6484
SF3B1 -6469
KRR1 -6432
RPS28 -6429
XPOT -6407
PSME1 -6399
ADAT2 -6386
PRPF8 -6374
PSMA5 -6362
RPL36 -6343
RBM17 -6331
THG1L -6318
NOP2 -6275
RPL8 -6274
PDCD7 -6173
GEMIN8 -6108
POM121C -6074
SNRNP200 -6070
RPL27 -6068
RPL41 -6065
RNMT -6020
ELAVL1 -5954
PSMC5 -5909
SF3A1 -5895
CLNS1A -5864
BYSL -5863
WDR36 -5853
MT-ND1 -5852
RBM28 -5810
RPL39 -5790
DHX37 -5761
DDX1 -5751
NHP2 -5747
BCAS2 -5731
LSM4 -5680
NUP133 -5674
PRKCA -5667
MNAT1 -5650
MTO1 -5635
RPS19 -5616
SNRNP48 -5596
PAIP1 -5582
DHX9 -5556
RPL13 -5550
SRSF3 -5528
RPS26 -5524
LSM7 -5504
PPWD1 -5498
MRM3 -5496
PES1 -5491
SNRNP70 -5483
UTP6 -5444
FAM98B -5439
CDKAL1 -5422
TGS1 -5399
RPS15 -5342
NUP54 -5340
LAGE3 -5316
RPS24 -5310
NT5C3B -5245
POP5 -5173
PUS1 -5165
BOP1 -5141
THADA -5123
PNRC2 -5116
EXOSC10 -5112
POLR2B -5111
SF3A2 -5104
SRSF2 -5095
PPIE -5064
THOC1 -5006
C2orf49 -4992
SNRPA1 -4867
TRMT5 -4833
SLBP -4830
RPL37A -4774
LSM8 -4763
SNRPD2 -4757
MTREX -4734
SMN1 -4719
SRSF7 -4657
HNRNPH1 -4617
TFB1M -4603
LTV1 -4592
POP1 -4584
PSMD10 -4578
RRP7A -4574
RPSA -4559
U2SURP -4531
DHX15 -4502
GTPBP3 -4453
SMG6 -4443
NUP153 -4433
SNRPD3 -4404
NUP210 -4373
WDR18 -4348
PSMA3 -4338
PARN -4316
PTBP1 -4302
MT-CO3 -4247
DCAF13 -4245
XPO1 -4204
OSGEP -4189
CTU2 -4179
RPL36AL -4148
DDX6 -4138
TPR -4127
CSTF2T -4089
CWC22 -4076
MAGOHB -4045
FIP1L1 -3955
DIS3 -3916
POLR2K -3902
RPLP1 -3887
HBS1L -3847
WDR4 -3834
DDX5 -3820
RTRAF -3817
PPIL4 -3815
ZC3H11A -3770
SNRPD1 -3757
DDX21 -3746
FTSJ1 -3726
ELAC2 -3686
PRORP -3614
POLR2H -3611
CRNKL1 -3606
PSME2 -3570
SNRPB -3546
ALYREF -3518
TNPO1 -3493
PABPC1 -3482
TRMT1 -3450
MT-ND6 -3405
XRN1 -3373
PRPF38A -3334
RIOK1 -3329
METTL14 -3289
SRRT -3284
MRM2 -3190
MT-ND5 -3188
NUP93 -3163
UTP14A -3160
RANBP2 -3109
SRSF1 -3108
EDC4 -3073
UPF3B -3065
CNOT4 -3031
FCF1 -3010
RBM8A -2980
MT-ND3 -2969
TRMT44 -2946
CHERP -2861
GEMIN6 -2834
METTL3 -2808
CSTF2 -2788
NUP42 -2718
SUPT5H -2649
TRNT1 -2576
POLR2C -2566
PPIL3 -2544
HNRNPD -2497
UBB -2442
RPP14 -2433
SNRPB2 -2429
LSM2 -2392
DDX42 -2376
MPHOSPH6 -2335
CPSF4 -2319
PQBP1 -2305
POM121 -2295
TRMU -2286
H19 -2242
PCBP2 -2170
PRPF31 -2159
DNAJC8 -2118
SRRM1 -2111
MT-CYB -2095
CNOT10 -2083
PSMA2 -2032
HSPB1 -2023
PSMB1 -1960
RPL28 -1952
MAGOH -1931
SMG5 -1876
ADAT1 -1762
SLU7 -1726
NUP85 -1717
TRIT1 -1701
SMG1 -1661
UTP14C -1630
POLR2I -1599
CCAR1 -1587
RNPC3 -1544
ZCRB1 -1532
ISY1 -1477
UTP3 -1460
CHTOP -1452
UBA52 -1437
NUP37 -1424
THOC2 -1413
DHX16 -1369
PRPF3 -1341
PPP2R2A -1333
WDR12 -1301
PUF60 -1289
APOBEC2 -1280
HNRNPF -1277
WDR61 -1268
NUP50 -1242
SNRNP27 -1210
NCBP1 -1125
SF1 -1103
PSME4 -1087
CNOT1 -1042
FAU -1029
TRMT12 -949
HNRNPUL1 -917
EIF4A3 -915
CWC27 -901
ADARB1 -896
GEMIN2 -805
HNRNPU -781
PHF5A -696
DDX39A -651
GTF2H5 -649
YWHAZ -647
SNRPC -613
XAB2 -562
CNOT2 -518
WTAP -501
POP4 -441
YBX1 -423
PRPF40A -396
PSMB10 -372
TRMT112 -370
TSR3 -358
MAPK11 -273
FUS -263
CNOT8 -257
WDR33 -253
UPF2 -229
RPP21 -200
MT-RNR2 -141
PSMA4 -118
RPL39L -69
ISG20L2 -43
IGF2BP2 -34
ZFP36 -17
LSM3 21
MT-ATP6 36
TBL3 55
NUP98 175
PSMD14 225
EXOSC3 280
PUS3 349
TRA2B 372
NUP62 395
THOC6 473
MT-CO1 507
RRP36 511
C1D 531
CWC15 544
KHSRP 560
USP39 611
TYW5 618
AAAS 627
SMG8 663
SNRNP25 671
SF3B5 672
MT-CO2 729
APOBEC3C 737
GTF2H2 765
DDX46 825
RTCB 848
RRP1 874
U2AF2 883
URM1 899
RNGTT 940
SYF2 941
POP7 963
U2AF1L4 985
DHX38 1001
MT-TF 1008
PSMF1 1056
LSM1 1147
RBM22 1158
PAN3 1204
MT-TS1 1223
CNOT11 1260
UTP11 1268
AQR 1282
CDC5L 1283
APOBEC3H 1348
PSMC4 1389
THOC7 1391
RPS4Y1 1461
DDX52 1503
SNW1 1506
PSMD7 1547
ZRSR2 1562
PRMT5 1768
RBM5 1791
EDC3 1813
PAN2 1833
SMNDC1 1892
MT-ATP8 1944
SARNP 1972
ERI1 1991
YWHAB 2038
DDX39B 2041
PAPOLA 2096
EIF4E 2104
PSMC3 2182
DCPS 2282
NSUN6 2287
GTF2H4 2296
WBP4 2342
RPS9 2392
PCF11 2498
IGF2BP3 2536
EXOSC1 2569
PABPN1 2573
SF3B2 2587
HNRNPK 2644
RIOK3 2755
RPS27L 2784
SF3B6 2791
PPIL6 2992
QTRT2 3042
PRPF4 3084
ENPP2 3130
MT-ND4L 3155
SRRM2 3184
HNRNPM 3201
MT-TE 3244
MT-TY 3249
HNRNPC 3313
CTU1 3335
CDC40 3360
SNRPA 3417
POLR2L 3450
PSMA1 3451
TRDMT1 3457
PSMC6 3483
CWC25 3513
FTSJ3 3515
ADAR 3524
CLP1 3627
TFIP11 3706
PSMB4 3707
U2AF1 3739
UTP18 3740
DCP2 3745
PSMD13 3770
SNRPG 3835
MT-TA 3873
SF3B4 3986
A1CF 3988
GPKOW 4101
NSUN4 4135
PSMD3 4177
DDX49 4194
CNOT6 4214
SENP3 4233
PRCC 4237
PSMA6 4263
ETF1 4300
SART1 4376
PSMC2 4457
SYMPK 4502
MT-TV 4515
CTNNBL1 4575
CPSF2 4583
PPP2R1A 4593
MT-TN 4608
PSMB2 4680
GEMIN7 4800
CPSF1 4828
CPSF7 4872
UBC 4874
PPP2CA 4882
SNUPN 4907
CDK7 4908
MT-TL1 5025
RAE1 5040
NSUN2 5093
PCBP1 5106
POLR2E 5238
GTF2F2 5263
LSM6 5419
ERCC3 5421
PSMB8 5433
SKIV2L 5461
PSMD8 5474
TRMT6 5486
BUD31 5489
GTF2F1 5494
PSMD2 5544
MT-TC 5567
GLE1 5575
POLR2G 5695
RPL3L 5700
PSMD12 5714
POLR2F 5738
HNRNPL 5742
NOL12 5766
PSMC1 5778
MT-ND4 5850
EIF4A1 5928
PSMD5 6029
DDX23 6081
AKT1 6133
DUS2 6141
RPL26L1 6187
CSTF3 6324
HNRNPA2B1 6339
PSMD1 6354
POLR2A 6387
HSD17B10 6466
MAPKAPK2 6495
ZFP36L1 6578
TXNL4A 6590
PSME3 6605
CPSF3 6658
HSPA1A 6708
HNRNPH2 6735
GPRC5A 6765
SUGP1 6788
SEC13 6793
ADAT3 6884
UPF1 6979
PSMD11 7057
SRSF4 7078
CASC3 7085
CCNH 7145
TRMT10A 7232
CSNK1D 7458
NOC4L 7461
TSEN34 7554
LSM10 7576
NUP58 7628
SEM1 7739
APOBEC3B 7939
PSMB7 7941
POLR2J 7983
NXF1 8049
SNRNP35 8105
ERCC2 8166
CNOT3 8403
CD44 8470
EFTUD2 8476
PSMB5 8625
PSMA7 8719
PSMD6 8745
EXOSC4 8895
PSMD9 9005
ZBTB8OS 9012
CD2BP2 9074
SMG9 9218
SRSF9 9246
PSMB6 9262
XRN2 9350
SMG7 9427
PSMB3 9902
EIF4G1 9922
POLDIP3 10060
THOC5 10063
NUP214 10124
PATL1 10198
PSMD4 10295
ZMAT5 10301
ACTB 10419
ANP32A 10461
MAPK14 10466
NOP10 10793
TNFSF13 11107
RPPH1 11164
APOBEC3A 11250
TRMT9B 11352
SNORD3A 11429
PRKCD 11506


Translation

Translation
1268
set Translation
setSize 295
pANOVA 4.36e-32
s.dist -0.398
p.adjustANOVA 9.91e-30



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
EEF1A1 -9389
RPL23A -9382
RPL5 -9359
EIF4A2 -9355
NARS2 -9337
GFM1 -9259
RPS3A -9257
MRPS30 -9238
MRPS6 -9227
RPS6 -9170
RPL7 -9134
EEF1B2 -9090
RPL4 -9065
EARS2 -8978
EEF1G -8961
RPL22 -8915
N6AMT1 -8889

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
EEF1A1 -9389
RPL23A -9382
RPL5 -9359
EIF4A2 -9355
NARS2 -9337
GFM1 -9259
RPS3A -9257
MRPS30 -9238
MRPS6 -9227
RPS6 -9170
RPL7 -9134
EEF1B2 -9090
RPL4 -9065
EARS2 -8978
EEF1G -8961
RPL22 -8915
N6AMT1 -8889
LARS1 -8879
EIF3B -8874
MRPS33 -8868
RPS3 -8856
RPS25 -8832
MRPL50 -8779
RPL21 -8773
RPS27A -8722
IARS1 -8710
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
EIF3E -8600
SRPRB -8515
FARS2 -8512
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
EIF1AX -8394
MRPS18B -8387
MRPS27 -8372
RPS14 -8337
GSPT2 -8336
RPS23 -8334
EIF4B -8328
RPL10 -8318
LARS2 -8305
RPS27 -8260
RPLP2 -8255
RPL36A -8130
MARS2 -8117
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
MRPL17 -7946
RPL11 -7928
RPL32 -7914
RPS15A -7912
TRAM1 -7911
RPL22L1 -7828
MRPS25 -7801
RPL30 -7783
RPL18 -7781
MRPL46 -7776
EIF3L -7766
RPL35 -7710
AARS2 -7669
RPL26 -7648
KARS1 -7645
RPS4X -7636
RPS10 -7629
RPL24 -7626
FARSB -7620
RPS16 -7617
RPL18A -7609
WARS2 -7547
RPL31 -7521
MRPS17 -7515
MRPL49 -7488
RPL9 -7451
AARS1 -7422
RPL15 -7380
RPS13 -7375
MRPL24 -7374
RPL7A -7296
RPS18 -7288
MRPL48 -7205
RPS8 -7161
RPS17 -7134
EEF2 -7073
RPL19 -7006
RPL23 -6933
EPRS1 -6849
RPS29 -6791
MRPL3 -6766
DARS1 -6758
RPS11 -6742
RPS21 -6706
RPL37 -6660
EEF1A1P5 -6596
RPL38 -6589
GSPT1 -6576
MRPL38 -6536
MT-RNR1 -6484
MRPL1 -6477
MRPS9 -6468
MRPS14 -6456
RPS28 -6429
SARS1 -6425
RPL36 -6343
MRPL35 -6300
RPL8 -6274
MRPL45 -6248
MRPS2 -6123
RPL27 -6068
RPL41 -6065
SARS2 -6041
EIF3J -6001
MRPL9 -5999
DAP3 -5995
EIF5B -5931
EIF3H -5894
RPL39 -5790
EIF3M -5620
RPS19 -5616
MRPL32 -5558
RPL13 -5550
RPS26 -5524
PPA1 -5482
RPS15 -5342
RPS24 -5310
MRPL42 -5308
SEC11C -5303
MRPL54 -5211
AIMP1 -5088
MRPL11 -5071
MRPS7 -5007
EEF1D -4995
EIF2B3 -4898
SRP72 -4824
HARS1 -4780
RPL37A -4774
IARS2 -4691
PTCD3 -4586
RPSA -4559
MRPL14 -4414
SRP9 -4398
MRPL39 -4366
MRPS12 -4356
VARS2 -4343
EIF3D -4337
RPL36AL -4148
MRPL30 -4147
MRPS31 -4116
MRPL19 -4110
MRPS28 -3921
MRPL34 -3892
RPLP1 -3887
EIF3C -3750
EIF3F -3748
PARS2 -3729
MRPL43 -3700
MRPL55 -3601
PABPC1 -3482
TSFM -3472
MRPL12 -3417
MRPL15 -3362
EIF2S1 -3350
MRPS10 -3348
SEC61A2 -3262
QARS1 -3062
MRPS35 -3044
MRPL41 -2920
PPA2 -2874
MRPS21 -2793
EIF3I -2671
SSR1 -2645
AIMP2 -2623
MRPL57 -2601
YARS2 -2577
SRP68 -2562
SPCS2 -2449
EIF2B5 -2425
MRRF -2404
SSR2 -2362
SEC61G -2328
MRPS22 -2326
MRPL37 -2251
MRPS26 -2022
SPCS1 -2007
RPL28 -1952
EEF1A2 -1947
SPCS3 -1816
VARS1 -1755
GADD45GIP1 -1746
EIF3G -1676
MRPS23 -1564
EIF3A -1537
FARSA -1474
MRPL47 -1448
UBA52 -1437
RARS1 -1110
FAU -1029
MRPL58 -1009
MRPS34 -978
MRPL2 -971
TARS1 -811
MRPL27 -697
SSR3 -664
SRP19 -483
EIF5 -416
TRMT112 -370
GFM2 -362
MRPS16 -360
EIF3K -298
MT-RNR2 -141
RARS2 -78
RPL39L -69
NARS1 -55
MTFMT 190
MRPL18 194
MRPL40 273
EIF2S2 297
MRPS18C 334
MTIF2 475
MRPS15 1207
MRPL21 1215
EIF2S3 1308
MRPS36 1368
RPS4Y1 1461
EIF2B1 1607
MRPL13 1696
MRPL20 1881
MRPL22 1912
SSR4 1961
EIF4E 2104
EEF1E1 2209
MRPL44 2241
MRPL36 2321
YARS1 2340
RPS9 2392
MRPS18A 2478
MRPS24 2522
MRPL4 2604
RPS27L 2784
DARS2 2882
ERAL1 3081
MRPL16 3317
SEC61A1 3976
MTIF3 3990
RPN1 4038
MRPL51 4065
ETF1 4300
OXA1L 4368
MTRF1L 4426
APEH 4454
MT-TV 4515
SEC61B 4523
MRPS11 4616
MRPL33 4926
SRP14 5005
HARS2 5027
EIF2B2 5069
GARS1 5314
MRPL10 5324
EIF4EBP1 5335
TARS2 5460
AURKAIP1 5462
SRPRA 5496
RPL3L 5700
MRPS5 5888
EIF4A1 5928
CHCHD1 6111
RPL26L1 6187
TUFM 6200
SRP54 6468
EIF2B4 6686
MRPL23 6696
RPN2 7108
SEC11A 7174
WARS1 7325
EIF4H 7435
MRPL53 7456
DDOST 7465
MRPL52 8490
MARS1 9700
CARS2 9768
EIF4G1 9922
MRPL28 10313
CARS1 10957


Formation of a pool of free 40S subunits

Formation of a pool of free 40S subunits
392
set Formation of a pool of free 40S subunits
setSize 100
pANOVA 5.67e-32
s.dist -0.68
p.adjustANOVA 1.1e-29



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
EIF3B -8874
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
EIF3E -8600

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
EIF3B -8874
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
EIF3E -8600
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
EIF1AX -8394
RPS14 -8337
RPS23 -8334
RPL10 -8318
RPS27 -8260
RPLP2 -8255
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
EIF3L -7766
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
RPS16 -7617
RPL18A -7609
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
RPL7A -7296
RPS18 -7288
RPS8 -7161
RPS17 -7134
RPL19 -7006
RPL23 -6933
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPL37 -6660
RPL38 -6589
RPS28 -6429
RPL36 -6343
RPL8 -6274
RPL27 -6068
RPL41 -6065
EIF3J -6001
EIF3H -5894
RPL39 -5790
EIF3M -5620
RPS19 -5616
RPL13 -5550
RPS26 -5524
RPS15 -5342
RPS24 -5310
RPL37A -4774
RPSA -4559
EIF3D -4337
RPL36AL -4148
RPLP1 -3887
EIF3C -3750
EIF3F -3748
EIF3I -2671
RPL28 -1952
EIF3G -1676
EIF3A -1537
UBA52 -1437
FAU -1029
EIF3K -298
RPL39L -69
RPS4Y1 1461
RPS9 2392
RPS27L 2784
RPL3L 5700
RPL26L1 6187


Eukaryotic Translation Elongation

Eukaryotic Translation Elongation
350
set Eukaryotic Translation Elongation
setSize 93
pANOVA 7.89e-32
s.dist -0.703
p.adjustANOVA 1.34e-29



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
EEF1A1 -9389
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
EEF1B2 -9090
RPL4 -9065
EEF1G -8961
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
EEF1A1 -9389
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
EEF1B2 -9090
RPL4 -9065
EEF1G -8961
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
RPS14 -8337
RPS23 -8334
RPL10 -8318
RPS27 -8260
RPLP2 -8255
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
RPS16 -7617
RPL18A -7609
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
RPL7A -7296
RPS18 -7288
RPS8 -7161
RPS17 -7134
EEF2 -7073
RPL19 -7006
RPL23 -6933
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPL37 -6660
EEF1A1P5 -6596
RPL38 -6589
RPS28 -6429
RPL36 -6343
RPL8 -6274
RPL27 -6068
RPL41 -6065
RPL39 -5790
RPS19 -5616
RPL13 -5550
RPS26 -5524
RPS15 -5342
RPS24 -5310
EEF1D -4995
RPL37A -4774
RPSA -4559
RPL36AL -4148
RPLP1 -3887
RPL28 -1952
EEF1A2 -1947
UBA52 -1437
FAU -1029
RPL39L -69
RPS4Y1 1461
RPS9 2392
RPS27L 2784
RPL3L 5700
RPL26L1 6187


Peptide chain elongation

Peptide chain elongation
807
set Peptide chain elongation
setSize 88
pANOVA 2.46e-30
s.dist -0.705
p.adjustANOVA 3.72e-28



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
EEF1A1 -9389
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
EEF1A1 -9389
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
RPS14 -8337
RPS23 -8334
RPL10 -8318
RPS27 -8260
RPLP2 -8255
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
RPS16 -7617
RPL18A -7609
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
RPL7A -7296
RPS18 -7288
RPS8 -7161
RPS17 -7134
EEF2 -7073
RPL19 -7006
RPL23 -6933
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPL37 -6660
RPL38 -6589
RPS28 -6429
RPL36 -6343
RPL8 -6274
RPL27 -6068
RPL41 -6065
RPL39 -5790
RPS19 -5616
RPL13 -5550
RPS26 -5524
RPS15 -5342
RPS24 -5310
RPL37A -4774
RPSA -4559
RPL36AL -4148
RPLP1 -3887
RPL28 -1952
UBA52 -1437
FAU -1029
RPL39L -69
RPS4Y1 1461
RPS9 2392
RPS27L 2784
RPL3L 5700
RPL26L1 6187


GTP hydrolysis and joining of the 60S ribosomal subunit

GTP hydrolysis and joining of the 60S ribosomal subunit
434
set GTP hydrolysis and joining of the 60S ribosomal subunit
setSize 111
pANOVA 8.89e-30
s.dist -0.622
p.adjustANOVA 1.1e-27



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
EIF4A2 -9355
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
EIF3B -8874
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
EIF4A2 -9355
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
EIF3B -8874
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
EIF3E -8600
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
EIF1AX -8394
RPS14 -8337
RPS23 -8334
EIF4B -8328
RPL10 -8318
RPS27 -8260
RPLP2 -8255
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
EIF3L -7766
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
RPS16 -7617
RPL18A -7609
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
RPL7A -7296
RPS18 -7288
RPS8 -7161
RPS17 -7134
RPL19 -7006
RPL23 -6933
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPL37 -6660
RPL38 -6589
RPS28 -6429
RPL36 -6343
RPL8 -6274
RPL27 -6068
RPL41 -6065
EIF3J -6001
EIF5B -5931
EIF3H -5894
RPL39 -5790
EIF3M -5620
RPS19 -5616
RPL13 -5550
RPS26 -5524
RPS15 -5342
RPS24 -5310
RPL37A -4774
RPSA -4559
EIF3D -4337
RPL36AL -4148
RPLP1 -3887
EIF3C -3750
EIF3F -3748
EIF2S1 -3350
EIF3I -2671
RPL28 -1952
EIF3G -1676
EIF3A -1537
UBA52 -1437
FAU -1029
EIF5 -416
EIF3K -298
RPL39L -69
EIF2S2 297
EIF2S3 1308
RPS4Y1 1461
EIF4E 2104
RPS9 2392
RPS27L 2784
RPL3L 5700
EIF4A1 5928
RPL26L1 6187
EIF4H 7435
EIF4G1 9922


Selenocysteine synthesis

Selenocysteine synthesis
1060
set Selenocysteine synthesis
setSize 92
pANOVA 9.58e-30
s.dist -0.682
p.adjustANOVA 1.1e-27



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498
RPL34 -8489

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
RPS14 -8337
RPS23 -8334
RPL10 -8318
RPS27 -8260
RPLP2 -8255
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
RPS16 -7617
RPL18A -7609
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
RPL7A -7296
RPS18 -7288
RPS8 -7161
RPS17 -7134
SEPSECS -7064
RPL19 -7006
RPL23 -6933
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPL37 -6660
RPL38 -6589
RPS28 -6429
SARS1 -6425
RPL36 -6343
RPL8 -6274
SECISBP2 -6069
RPL27 -6068
RPL41 -6065
RPL39 -5790
RPS19 -5616
RPL13 -5550
RPS26 -5524
RPS15 -5342
RPS24 -5310
EEFSEC -5238
RPL37A -4774
RPSA -4559
RPL36AL -4148
RPLP1 -3887
PSTK -3075
RPL28 -1952
UBA52 -1437
FAU -1029
RPL39L -69
RPS4Y1 1461
RPS9 2392
RPS27L 2784
RPL3L 5700
RPL26L1 6187
SEPHS2 7242


L13a-mediated translational silencing of Ceruloplasmin expression

L13a-mediated translational silencing of Ceruloplasmin expression
588
set L13a-mediated translational silencing of Ceruloplasmin expression
setSize 110
pANOVA 9.65e-30
s.dist -0.624
p.adjustANOVA 1.1e-27



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
EIF4A2 -9355
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
EIF3B -8874
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
EIF4A2 -9355
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
EIF3B -8874
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
EIF3E -8600
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
EIF1AX -8394
RPS14 -8337
RPS23 -8334
EIF4B -8328
RPL10 -8318
RPS27 -8260
RPLP2 -8255
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
EIF3L -7766
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
RPS16 -7617
RPL18A -7609
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
RPL7A -7296
RPS18 -7288
RPS8 -7161
RPS17 -7134
RPL19 -7006
RPL23 -6933
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPL37 -6660
RPL38 -6589
RPS28 -6429
RPL36 -6343
RPL8 -6274
RPL27 -6068
RPL41 -6065
EIF3J -6001
EIF3H -5894
RPL39 -5790
EIF3M -5620
RPS19 -5616
RPL13 -5550
RPS26 -5524
RPS15 -5342
RPS24 -5310
RPL37A -4774
RPSA -4559
EIF3D -4337
RPL36AL -4148
RPLP1 -3887
EIF3C -3750
EIF3F -3748
PABPC1 -3482
EIF2S1 -3350
EIF3I -2671
RPL28 -1952
EIF3G -1676
EIF3A -1537
UBA52 -1437
FAU -1029
EIF3K -298
RPL39L -69
EIF2S2 297
EIF2S3 1308
RPS4Y1 1461
EIF4E 2104
RPS9 2392
RPS27L 2784
RPL3L 5700
EIF4A1 5928
RPL26L1 6187
EIF4H 7435
EIF4G1 9922


Eukaryotic Translation Termination

Eukaryotic Translation Termination
352
set Eukaryotic Translation Termination
setSize 92
pANOVA 2.59e-29
s.dist -0.677
p.adjustANOVA 2.72e-27



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
N6AMT1 -8889
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
N6AMT1 -8889
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
RPS14 -8337
GSPT2 -8336
RPS23 -8334
RPL10 -8318
RPS27 -8260
RPLP2 -8255
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
RPS16 -7617
RPL18A -7609
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
RPL7A -7296
RPS18 -7288
RPS8 -7161
RPS17 -7134
RPL19 -7006
RPL23 -6933
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPL37 -6660
RPL38 -6589
GSPT1 -6576
RPS28 -6429
RPL36 -6343
RPL8 -6274
RPL27 -6068
RPL41 -6065
RPL39 -5790
RPS19 -5616
RPL13 -5550
RPS26 -5524
RPS15 -5342
RPS24 -5310
RPL37A -4774
RPSA -4559
RPL36AL -4148
RPLP1 -3887
RPL28 -1952
UBA52 -1437
FAU -1029
TRMT112 -370
RPL39L -69
RPS4Y1 1461
RPS9 2392
RPS27L 2784
ETF1 4300
APEH 4454
RPL3L 5700
RPL26L1 6187


Viral mRNA Translation

Viral mRNA Translation
1315
set Viral mRNA Translation
setSize 88
pANOVA 1.67e-28
s.dist -0.682
p.adjustANOVA 1.62e-26



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498
RPL34 -8489

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
RPS14 -8337
RPS23 -8334
RPL10 -8318
RPS27 -8260
RPLP2 -8255
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
RPS16 -7617
RPL18A -7609
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
RPL7A -7296
RPS18 -7288
RPS8 -7161
RPS17 -7134
RPL19 -7006
RPL23 -6933
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPL37 -6660
RPL38 -6589
RPS28 -6429
RPL36 -6343
RPL8 -6274
RPL27 -6068
RPL41 -6065
RPL39 -5790
RPS19 -5616
RPL13 -5550
RPS26 -5524
RPS15 -5342
RPS24 -5310
RPL37A -4774
RPSA -4559
RPL36AL -4148
RPLP1 -3887
GRSF1 -3125
RPL28 -1952
UBA52 -1437
FAU -1029
RPL39L -69
RPS4Y1 1461
RPS9 2392
RPS27L 2784
RPL3L 5700
RPL26L1 6187
DNAJC3 8291


Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
743
set Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
setSize 94
pANOVA 3.69e-28
s.dist -0.656
p.adjustANOVA 3.35e-26



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498
RPL34 -8489

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
RPS14 -8337
GSPT2 -8336
RPS23 -8334
RPL10 -8318
RPS27 -8260
RPLP2 -8255
NCBP2 -8212
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
RPS16 -7617
RPL18A -7609
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
RPL7A -7296
RPS18 -7288
RPS8 -7161
RPS17 -7134
RPL19 -7006
RPL23 -6933
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPL37 -6660
RPL38 -6589
GSPT1 -6576
RPS28 -6429
RPL36 -6343
RPL8 -6274
RPL27 -6068
RPL41 -6065
RPL39 -5790
RPS19 -5616
RPL13 -5550
RPS26 -5524
RPS15 -5342
RPS24 -5310
RPL37A -4774
RPSA -4559
RPL36AL -4148
RPLP1 -3887
PABPC1 -3482
RPL28 -1952
UBA52 -1437
NCBP1 -1125
FAU -1029
RPL39L -69
RPS4Y1 1461
RPS9 2392
RPS27L 2784
ETF1 4300
RPL3L 5700
RPL26L1 6187
UPF1 6979
EIF4G1 9922


Influenza Viral RNA Transcription and Replication

Influenza Viral RNA Transcription and Replication
527
set Influenza Viral RNA Transcription and Replication
setSize 135
pANOVA 4.19e-28
s.dist -0.547
p.adjustANOVA 3.57e-26



Top enriched genes

Top 20 genes
GeneID Gene Rank
IPO5 -9839
NDC1 -9817
RPL3 -9701
RPS2 -9635
NUP35 -9626
NUP88 -9430
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
PARP1 -9133
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
NUP107 -8801
SEH1L -8792
RPL21 -8773

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IPO5 -9839
NDC1 -9817
RPL3 -9701
RPS2 -9635
NUP35 -9626
NUP88 -9430
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
PARP1 -9133
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
NUP107 -8801
SEH1L -8792
RPL21 -8773
RPS27A -8722
NUP160 -8699
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
RPS14 -8337
RPS23 -8334
RPL10 -8318
RPS27 -8260
RPLP2 -8255
POLR2D -8160
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
RPL22L1 -7828
NUP43 -7792
RPL30 -7783
RPL18 -7781
RPL35 -7710
RPL26 -7648
RPS4X -7636
NUP155 -7633
RPS10 -7629
RPL24 -7626
RPS16 -7617
RPL18A -7609
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
RPL7A -7296
NUP188 -7295
RPS18 -7288
RPS8 -7161
RPS17 -7134
NUP205 -7051
RPL19 -7006
RPL23 -6933
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPL37 -6660
RPL38 -6589
RPS28 -6429
RPL36 -6343
RPL8 -6274
POM121C -6074
RPL27 -6068
RPL41 -6065
RPL39 -5790
NUP133 -5674
RPS19 -5616
RPL13 -5550
RPS26 -5524
RPS15 -5342
NUP54 -5340
RPS24 -5310
POLR2B -5111
HSP90AA1 -5083
RPL37A -4774
RPSA -4559
NUP153 -4433
NUP210 -4373
RPL36AL -4148
TPR -4127
POLR2K -3902
RPLP1 -3887
POLR2H -3611
NUP93 -3163
GRSF1 -3125
RANBP2 -3109
NUP42 -2718
POLR2C -2566
POM121 -2295
RPL28 -1952
NUP85 -1717
POLR2I -1599
UBA52 -1437
NUP37 -1424
NUP50 -1242
FAU -1029
RPL39L -69
NUP98 175
NUP62 395
AAAS 627
RPS4Y1 1461
RPS9 2392
RPS27L 2784
POLR2L 3450
RAE1 5040
POLR2E 5238
GTF2F2 5263
GTF2F1 5494
POLR2G 5695
RPL3L 5700
POLR2F 5738
RPL26L1 6187
POLR2A 6387
SEC13 6793
NUP58 7628
POLR2J 7983
DNAJC3 8291
NUP214 10124


Cap-dependent Translation Initiation

Cap-dependent Translation Initiation
142
set Cap-dependent Translation Initiation
setSize 118
pANOVA 5.14e-28
s.dist -0.584
p.adjustANOVA 3.89e-26



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
EIF4A2 -9355
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
EIF3B -8874
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
EIF4A2 -9355
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
EIF3B -8874
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
EIF3E -8600
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
EIF1AX -8394
RPS14 -8337
RPS23 -8334
EIF4B -8328
RPL10 -8318
RPS27 -8260
RPLP2 -8255
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
EIF3L -7766
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
RPS16 -7617
RPL18A -7609
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
RPL7A -7296
RPS18 -7288
RPS8 -7161
RPS17 -7134
RPL19 -7006
RPL23 -6933
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPL37 -6660
RPL38 -6589
RPS28 -6429
RPL36 -6343
RPL8 -6274
RPL27 -6068
RPL41 -6065
EIF3J -6001
EIF5B -5931
EIF3H -5894
RPL39 -5790
EIF3M -5620
RPS19 -5616
RPL13 -5550
RPS26 -5524
RPS15 -5342
RPS24 -5310
EIF2B3 -4898
RPL37A -4774
RPSA -4559
EIF3D -4337
RPL36AL -4148
RPLP1 -3887
EIF3C -3750
EIF3F -3748
PABPC1 -3482
EIF2S1 -3350
EIF3I -2671
EIF2B5 -2425
RPL28 -1952
EIF3G -1676
EIF3A -1537
UBA52 -1437
FAU -1029
EIF5 -416
EIF3K -298
RPL39L -69
EIF2S2 297
EIF2S3 1308
RPS4Y1 1461
EIF2B1 1607
EIF4E 2104
RPS9 2392
RPS27L 2784
EIF2B2 5069
EIF4EBP1 5335
RPL3L 5700
EIF4A1 5928
RPL26L1 6187
EIF2B4 6686
EIF4H 7435
EIF4G1 9922


Eukaryotic Translation Initiation

Eukaryotic Translation Initiation
351
set Eukaryotic Translation Initiation
setSize 118
pANOVA 5.14e-28
s.dist -0.584
p.adjustANOVA 3.89e-26



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
EIF4A2 -9355
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
EIF3B -8874
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
EIF4A2 -9355
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
EIF3B -8874
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
EIF3E -8600
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
EIF1AX -8394
RPS14 -8337
RPS23 -8334
EIF4B -8328
RPL10 -8318
RPS27 -8260
RPLP2 -8255
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
EIF3L -7766
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
RPS16 -7617
RPL18A -7609
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
RPL7A -7296
RPS18 -7288
RPS8 -7161
RPS17 -7134
RPL19 -7006
RPL23 -6933
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPL37 -6660
RPL38 -6589
RPS28 -6429
RPL36 -6343
RPL8 -6274
RPL27 -6068
RPL41 -6065
EIF3J -6001
EIF5B -5931
EIF3H -5894
RPL39 -5790
EIF3M -5620
RPS19 -5616
RPL13 -5550
RPS26 -5524
RPS15 -5342
RPS24 -5310
EIF2B3 -4898
RPL37A -4774
RPSA -4559
EIF3D -4337
RPL36AL -4148
RPLP1 -3887
EIF3C -3750
EIF3F -3748
PABPC1 -3482
EIF2S1 -3350
EIF3I -2671
EIF2B5 -2425
RPL28 -1952
EIF3G -1676
EIF3A -1537
UBA52 -1437
FAU -1029
EIF5 -416
EIF3K -298
RPL39L -69
EIF2S2 297
EIF2S3 1308
RPS4Y1 1461
EIF2B1 1607
EIF4E 2104
RPS9 2392
RPS27L 2784
EIF2B2 5069
EIF4EBP1 5335
RPL3L 5700
EIF4A1 5928
RPL26L1 6187
EIF2B4 6686
EIF4H 7435
EIF4G1 9922


Response of EIF2AK4 (GCN2) to amino acid deficiency

Response of EIF2AK4 (GCN2) to amino acid deficiency
1007
set Response of EIF2AK4 (GCN2) to amino acid deficiency
setSize 100
pANOVA 9.21e-28
s.dist -0.631
p.adjustANOVA 6.61e-26



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498
RPL34 -8489

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
RPS14 -8337
RPS23 -8334
RPL10 -8318
RPS27 -8260
RPLP2 -8255
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
RPS16 -7617
RPL18A -7609
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
RPL7A -7296
RPS18 -7288
RPS8 -7161
RPS17 -7134
RPL19 -7006
RPL23 -6933
RPS29 -6791
IMPACT -6768
RPS11 -6742
RPS21 -6706
RPL37 -6660
RPL38 -6589
GCN1 -6541
RPS28 -6429
RPL36 -6343
RPL8 -6274
ASNS -6196
RPL27 -6068
RPL41 -6065
RPL39 -5790
RPS19 -5616
RPL13 -5550
RPS26 -5524
RPS15 -5342
RPS24 -5310
ATF2 -4941
RPL37A -4774
RPSA -4559
RPL36AL -4148
RPLP1 -3887
EIF2S1 -3350
ATF3 -2894
RPL28 -1952
EIF2AK4 -1601
UBA52 -1437
TRIB3 -1365
FAU -1029
ATF4 -994
RPL39L -69
EIF2S2 297
EIF2S3 1308
RPS4Y1 1461
CEBPG 1958
RPS9 2392
RPS27L 2784
DDIT3 3500
RPL3L 5700
RPL26L1 6187
CEBPB 11028


Gene expression (Transcription)

Gene expression (Transcription)
443
set Gene expression (Transcription)
setSize 1323
pANOVA 4.44e-27
s.dist -0.176
p.adjustANOVA 3.02e-25



Top enriched genes

Top 20 genes
GeneID Gene Rank
RORC -9883
KIT -9844
TCF7 -9843
NPM1 -9836
NDC1 -9817
CAMK4 -9799
THOC3 -9796
GLS -9763
NR3C2 -9761
POLR1E -9756
FOXO1 -9743
ZNF711 -9729
RBL2 -9700
DYRK2 -9696
ZNF33B -9689
NFATC2 -9680
PERP -9667
NFYB -9659
ZNF551 -9658
RPA1 -9657

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RORC -9883.0
KIT -9844.0
TCF7 -9843.0
NPM1 -9836.0
NDC1 -9817.0
CAMK4 -9799.0
THOC3 -9796.0
GLS -9763.0
NR3C2 -9761.0
POLR1E -9756.0
FOXO1 -9743.0
ZNF711 -9729.0
RBL2 -9700.0
DYRK2 -9696.0
ZNF33B -9689.0
NFATC2 -9680.0
PERP -9667.0
NFYB -9659.0
ZNF551 -9658.0
RPA1 -9657.0
RUNX2 -9648.0
PRKCQ -9643.0
ZNF420 -9642.0
PMAIP1 -9639.0
NUP35 -9626.0
WWP1 -9624.0
SUV39H1 -9613.0
PLD6 -9599.0
SUPT16H -9598.0
FBXO32 -9595.0
ZNF530 -9593.0
RORA -9585.0
GATA3 -9575.0
LEF1 -9568.0
ZIK1 -9567.0
ZNF549 -9560.0
HSPD1 -9514.0
LRPPRC -9513.0
ZNF136 -9491.0
POLR3H -9488.0
LSM11 -9482.0
PTPN4 -9478.0
RAD1 -9471.0
CAMK2D -9460.0
MLLT3 -9457.0
ZNF287 -9448.0
TFDP2 -9444.0
IGFBP3 -9434.0
NUP88 -9430.0
MYC -9418.0
STAT1 -9404.0
ZNF286A -9397.0
ANAPC1 -9394.0
NR1D2 -9362.0
MYBBP1A -9347.0
ZNF208 -9334.0
TNFRSF18 -9325.0
NR1D1 -9318.0
ZNF566 -9289.0
CCND2 -9246.0
GAMT -9243.0
ZNF548 -9218.0
DNMT1 -9203.0
ZNF671 -9191.0
ZNF431 -9149.0
TNRC6C -9142.0
PARP1 -9133.0
POLR1B -9131.0
ZNF14 -9130.0
CNOT6L -9114.0
WRN -9097.0
ZNF681 -9089.0
ZNF544 -9084.0
PCGF5 -9061.0
TFAM -9055.0
PRKRA -9050.0
SSRP1 -9045.0
RRN3 -9040.0
ZNF112 -9037.0
ZC3H8 -9035.0
ZNF583 -9026.0
ZNF568 -9016.0
RGCC -9009.0
PRR5 -9001.0
ZFP28 -8997.0
ZNF416 -8970.0
RUNX3 -8952.0
FASLG -8936.0
ING5 -8935.0
SIN3A -8913.0
UBTF -8885.0
CUL1 -8878.0
ZNF517 -8859.0
TFB2M -8854.0
GLI3 -8843.0
TP53RK -8827.0
FANCD2 -8817.0
PLXNA4 -8810.0
AUTS2 -8807.0
NUP107 -8801.0
ZNF184 -8799.0
SEH1L -8792.0
PRMT6 -8789.0
ZNF485 -8781.0
ERBB2 -8774.0
AKT3 -8761.0
EPC1 -8757.0
ZNF567 -8743.0
ZNF337 -8725.0
RPS27A -8722.0
ZNF473 -8717.0
ZNF202 -8715.0
GLS2 -8711.0
BMI1 -8707.0
NUP160 -8699.0
RFC3 -8694.0
ZNF354C -8658.0
ZNF749 -8639.0
NUDT21 -8636.0
ZNF74 -8635.0
TP53 -8613.0
PHAX -8612.0
CNOT7 -8609.0
ZNF664 -8578.0
YEATS4 -8569.0
CDK4 -8539.0
JMY -8535.0
ZNF599 -8495.0
ZNF302 -8478.0
ZNF211 -8472.0
ZNF559 -8449.0
ZNF708 -8431.0
CCNG1 -8400.0
BRD1 -8393.0
ZFP1 -8379.0
COX11 -8355.0
PPP1R13B -8332.0
ZNF30 -8321.0
GTF3A -8308.0
ZNF678 -8303.0
ZNF331 -8301.0
ZNF430 -8300.0
ZNF696 -8297.0
ZNF43 -8258.0
SMURF2 -8254.0
ZNF721 -8249.0
ZNF616 -8248.0
SCMH1 -8236.0
NCBP2 -8212.0
POLR3D -8194.0
ZNF354B -8182.0
POLR2D -8160.0
ZNF727 -8137.0
ZNF253 -8107.0
GPAM -8085.0
ZNF554 -8080.0
ZNF138 -8077.0
CDC23 -8076.0
ZNF786 -8075.0
RPA3 -8069.0
BTG2 -8011.0
GTF3C4 -8000.0
SRSF5 -7996.0
TRIM28 -7995.0
BLK -7991.0
TAF4B -7985.0
ZNF737 -7984.0
POLRMT -7974.0
GTF2H3 -7969.0
ITGA4 -7966.0
TET1 -7964.0
PHF1 -7884.0
KAT2A -7883.0
POLR3G -7858.0
PVALB -7854.0
CLDN5 -7851.0
SRSF11 -7838.0
GATA2 -7834.0
ZNF675 -7824.0
ZNF792 -7822.0
ZNF263 -7806.0
POLR1C -7797.0
NUP43 -7792.0
ZNF257 -7772.0
RAD17 -7742.0
RFC4 -7736.0
ZNF248 -7734.0
TDRKH -7725.0
MEAF6 -7722.0
WWOX -7721.0
MYBL1 -7704.0
ZNF707 -7688.0
SIRT1 -7685.0
PPP2R5C -7679.0
XPO5 -7674.0
KRBOX4 -7673.0
PRMT1 -7660.0
E2F6 -7656.0
PRDM1 -7655.0
ZNF571 -7638.0
NUP155 -7633.0
PSMB9 -7625.0
HDAC9 -7621.0
AEBP2 -7592.0
RAN -7577.0
ICE2 -7543.0
ZNF3 -7533.0
NR2C2AP -7518.0
INTS5 -7514.0
ATM -7513.0
ZSCAN25 -7509.0
CDKN1B -7508.0
MED10 -7505.0
ZNF519 -7492.0
FYTTD1 -7487.0
ZNF614 -7476.0
TCEA1 -7475.0
TGIF2 -7440.0
PIP4K2B -7436.0
ZNF101 -7429.0
ZNF597 -7426.0
CASP6 -7413.0
ZNF649 -7409.0
MSH2 -7399.0
ZNF432 -7398.0
ZNF570 -7391.0
CSTF1 -7377.0
TDRD6 -7363.0
SMARCC1 -7357.0
PPARD -7353.0
ZNF446 -7335.0
MAML2 -7323.0
RBBP7 -7322.0
ZNF773 -7319.0
YY1 -7301.0
ZNF343 -7298.0
NUP188 -7295.0
ZNF510 -7293.0
CBX5 -7291.0
ZNF266 -7285.0
HDAC2 -7259.0
ZNF777 -7250.0
ZNF529 -7243.0
ZNF682 -7242.0
TNKS1BP1 -7235.0
ZNF550 -7211.0
MECP2 -7198.0
ZNF317 -7195.0
ZNF2 -7189.0
ZNF540 -7187.0
ANAPC16 -7186.0
GTF2H1 -7185.0
ZNF17 -7178.0
PCBP4 -7141.0
ZNF582 -7125.0
TAF9B -7121.0
ZNF483 -7106.0
ZNF486 -7103.0
CCNC -7102.0
SRSF6 -7099.0
NUP205 -7051.0
ESR2 -7042.0
MTA3 -7037.0
FANCI -7036.0
ZNF600 -7033.0
RNPS1 -7032.0
DGCR8 -7022.0
CHD3 -7016.0
POLR3E -6993.0
SNRPE -6979.0
MED6 -6963.0
MDC1 -6961.0
ZNF793 -6927.0
ZNF772 -6917.0
DLL1 -6916.0
CENPJ -6905.0
TAF1A -6901.0
KMT2A -6885.0
ZNF383 -6874.0
PCNA -6841.0
PHC1 -6810.0
IL2RA -6803.0
L3MBTL2 -6802.0
ERCC6 -6781.0
ZFP30 -6773.0
BTG1 -6755.0
ZNF740 -6726.0
SNRPF -6725.0
E2F7 -6721.0
RBL1 -6718.0
ZNF584 -6710.0
SMAD3 -6699.0
TAF1D -6667.0
ZNF12 -6648.0
ZNF141 -6647.0
ZNF514 -6637.0
ZNF761 -6633.0
ZNF419 -6622.0
ZNF563 -6608.0
ZNF771 -6602.0
SESN1 -6578.0
ZNF493 -6569.0
ZNF799 -6567.0
TAF9 -6564.0
ZNF45 -6562.0
ZNF10 -6560.0
SSB -6556.0
ZNF324 -6487.0
ZNF543 -6479.0
SF3B1 -6469.0
ZNF492 -6453.0
CTLA4 -6445.0
POLR3F -6436.0
ZNF274 -6415.0
THRA -6404.0
PSME1 -6399.0
PSMA5 -6362.0
ZNF417 -6355.0
ZNF180 -6353.0
HENMT1 -6302.0
MGA -6292.0
ZNF662 -6282.0
DROSHA -6279.0
ZNF23 -6276.0
NOP2 -6275.0
H2BC9 -6264.0
BRIP1 -6240.0
COX20 -6229.0
ZNF470 -6183.0
ZNF175 -6179.0
TDRD12 -6166.0
ZNF300 -6165.0
SUZ12 -6160.0
KRBA1 -6145.0
ZNF212 -6117.0
SMARCA5 -6114.0
POM121C -6074.0
YWHAQ -6039.0
CHEK1 -6036.0
ZFP37 -6030.0
RNMT -6020.0
ZSCAN32 -5996.0
ZNF506 -5994.0
ZKSCAN8 -5986.0
ZNF564 -5972.0
SMAD4 -5969.0
AXIN1 -5965.0
IFNG -5957.0
MTF2 -5932.0
TAF3 -5912.0
PIP4K2A -5911.0
PSMC5 -5909.0
H2AZ2 -5901.0
COX16 -5896.0
ZFPM1 -5886.0
RICTOR -5883.0
PHF20 -5876.0
SMYD2 -5873.0
TSN -5870.0
THRB -5858.0
MBD3 -5834.0
ZNF714 -5800.0
SKP1 -5791.0
MAF -5776.0
ZNF140 -5768.0
MED30 -5762.0
RRM2 -5738.0
ZNF75A -5735.0
ZNF680 -5733.0
RPRD2 -5724.0
ZFP2 -5716.0
ZNF736 -5696.0
ZNF227 -5693.0
MED17 -5686.0
CCNT1 -5679.0
NUP133 -5674.0
YES1 -5662.0
MNAT1 -5650.0
ZNF135 -5640.0
NR2C1 -5634.0
PAX5 -5611.0
ICE1 -5610.0
ZFP90 -5598.0
EED -5587.0
ZNF461 -5579.0
TRPC3 -5571.0
CDK1 -5568.0
ZNF626 -5567.0
SETD1A -5546.0
SRSF3 -5528.0
SRC -5527.0
ZNF607 -5518.0
ZNF484 -5467.0
ZNF480 -5463.0
TAF5 -5438.0
TCF3 -5430.0
ZNF528 -5423.0
ZNF441 -5420.0
TGIF1 -5418.0
ZNF557 -5417.0
ZNF334 -5412.0
ZNF595 -5408.0
ZNF285 -5404.0
ATAD2 -5373.0
TP73 -5371.0
SGK1 -5363.0
NUP54 -5340.0
E2F5 -5304.0
ZNF677 -5291.0
PF4 -5240.0
ZNF77 -5236.0
ACTL6A -5233.0
CALM1 -5150.0
POLR1A -5143.0
ZNF154 -5129.0
POLR2B -5111.0
SRSF2 -5095.0
HSP90AA1 -5083.0
RAD9A -5073.0
ZNF860 -5072.0
ZNF726 -5039.0
ZNF398 -5024.0
SETD9 -5013.0
ZNF621 -5009.0
THOC1 -5006.0
ZNF606 -4990.0
ZNF439 -4984.0
BRF2 -4980.0
POLR3B -4975.0
RHNO1 -4965.0
MRE11 -4960.0
ATF2 -4941.0
TACO1 -4896.0
RBBP5 -4861.0
PPP1R13L -4855.0
ESR1 -4853.0
SLBP -4830.0
MYBL2 -4826.0
UXT -4808.0
SKI -4796.0
ZNF92 -4794.0
ZNF658 -4768.0
BCL2L14 -4758.0
NR4A2 -4739.0
DNMT3A -4737.0
ZNF33A -4735.0
ZNF235 -4716.0
PIWIL2 -4707.0
ZNF425 -4682.0
ZNF782 -4681.0
ZNF610 -4659.0
RBBP4 -4658.0
SRSF7 -4657.0
ZNF706 -4651.0
ZNF26 -4650.0
CDK6 -4636.0
CYCS -4630.0
RPA2 -4620.0
ZNF226 -4609.0
VENTX -4606.0
PSMD10 -4578.0
MYL9 -4572.0
SNAPC1 -4571.0
ZNF561 -4564.0
COX18 -4521.0
BRPF3 -4516.0
TXNIP -4515.0
SMAD7 -4508.0
SMARCD1 -4507.0
GTF2A1 -4500.0
MAX -4483.0
TRIAP1 -4446.0
NUP153 -4433.0
BLM -4432.0
CDK5R1 -4421.0
SNRPD3 -4404.0
NUP210 -4373.0
ZNF157 -4363.0
ZNF624 -4347.0
MAPKAPK5 -4344.0
PSMA3 -4338.0
ZNF273 -4297.0
ZNF415 -4294.0
EXO1 -4293.0
ZNF605 -4291.0
MT-CO3 -4247.0
PRKAB2 -4214.0
MED1 -4211.0
ZNF436 -4168.0
MTERF1 -4162.0
PRDX2 -4140.0
RABGGTB -4135.0
TPR -4127.0
ZNF268 -4119.0
ZNF70 -4112.0
ZNF75D -4103.0
CSTF2T -4089.0
RAD51D -4074.0
RAD50 -4065.0
PMS2 -4051.0
MAGOHB -4045.0
NR3C1 -4034.0
ZNF324B -4025.0
NR2C2 -4024.0
DNA2 -4017.0
NFIB -4010.0
ZNF100 -4004.0
RFC5 -3986.0
ZNF573 -3982.0
FIP1L1 -3955.0
RARG -3923.0
ANAPC5 -3910.0
POLR2K -3902.0
ZNF776 -3896.0
FOXP3 -3879.0
NR4A3 -3862.0
ZNF264 -3850.0
MEN1 -3826.0
FOS -3812.0
MEF2C -3791.0
ZC3H11A -3770.0
CREB1 -3751.0
DDX21 -3746.0
TAF1B -3742.0
CAV1 -3722.0
CCND1 -3717.0
ZFP14 -3704.0
CDK2 -3694.0
ELF1 -3678.0
MED13 -3648.0
ZNF699 -3639.0
DAXX -3631.0
POLR2H -3611.0
CHD4 -3602.0
ZNF627 -3589.0
PSME2 -3570.0
ZNF500 -3548.0
SNRPB -3546.0
TAF15 -3527.0
ZNF234 -3523.0
ALYREF -3518.0
PHC3 -3455.0
ZNF689 -3443.0
ZNF770 -3413.0
BDP1 -3398.0
TAF1 -3331.0
PIDD1 -3316.0
TNFRSF10A -3294.0
SRRT -3284.0
ZNF724 -3257.0
NFIX -3227.0
ZNF620 -3202.0
LDB1 -3194.0
NUP93 -3163.0
SESN3 -3156.0
GTF3C2 -3142.0
CBFB -3135.0
ZNF223 -3118.0
ZNF496 -3117.0
RANBP2 -3109.0
SRSF1 -3108.0
CASP2 -3098.0
TBP -3090.0
TAL1 -3086.0
NR4A1 -3071.0
UPF3B -3065.0
ZNF440 -3050.0
INTS4 -3048.0
CNOT4 -3031.0
RRP8 -3003.0
RBM8A -2980.0
ZNF738 -2974.0
COX6C -2943.0
SOCS4 -2911.0
PPP2R1B -2904.0
GTF2E1 -2903.0
ZNF221 -2892.0
RNF34 -2887.0
MYO1C -2881.0
ZNF418 -2878.0
NUAK1 -2825.0
ZNF569 -2823.0
ZNF426 -2817.0
SMARCA2 -2810.0
CCNE1 -2791.0
CSTF2 -2788.0
COX19 -2785.0
ATR -2784.0
ZNF19 -2752.0
TTF1 -2751.0
BAZ1B -2724.0
NUP42 -2718.0
PCGF6 -2701.0
ZNF222 -2699.0
MYB -2685.0
SUPT5H -2649.0
SMARCE1 -2634.0
ZNF785 -2631.0
BRD2 -2613.0
ZNF791 -2598.0
POLR2C -2566.0
RELA -2563.0
CDC27 -2558.0
ZNF615 -2556.0
ZNF577 -2545.0
ZNF433 -2539.0
CCNB1 -2524.0
TPX2 -2523.0
ZNF350 -2515.0
ZNF585B -2491.0
CHM -2462.0
ZNF250 -2447.0
UBB -2442.0
ZNF790 -2365.0
STUB1 -2360.0
ZFP69 -2359.0
ZNF692 -2346.0
ZNF596 -2344.0
BBC3 -2320.0
CPSF4 -2319.0
POM121 -2295.0
NR2F6 -2292.0
ZNF684 -2249.0
H19 -2242.0
ZNF224 -2234.0
ZNF521 -2233.0
CCNA1 -2231.0
H2BU1 -2206.0
ZNF625 -2189.0
RPTOR -2185.0
ANAPC2 -2172.0
RNF2 -2168.0
NFKB1 -2166.0
CTR9 -2160.0
KAT6A -2151.0
ZNF676 -2148.0
DEK -2126.0
UBE2C -2114.0
SRRM1 -2111.0
RRAGB -2098.0
POLR3GL -2090.0
CNOT10 -2083.0
TSNAX -2082.0
COX7C -2078.0
PSMA2 -2032.0
ZNF767P -2005.0
MOV10 -1996.0
MED31 -1991.0
FBXW7 -1985.0
PSMB1 -1960.0
MAGOH -1931.0
ZNF558 -1914.0
E2F8 -1908.0
ARID4B -1885.0
RFFL -1875.0
KAT2B -1851.0
CBX2 -1835.0
TOPBP1 -1834.0
H2AC6 -1829.0
ZNF709 -1764.0
ZNF41 -1759.0
CCNA2 -1727.0
SLU7 -1726.0
NUP85 -1717.0
ZNF585A -1657.0
RAD51 -1636.0
WDR5 -1634.0
CDC16 -1623.0
POLR2I -1599.0
MTA1 -1577.0
COX14 -1533.0
ATRIP -1520.0
RRAGC -1512.0
CHTOP -1452.0
BRPF1 -1446.0
JUN -1440.0
UBA52 -1437.0
NUP37 -1424.0
THOC2 -1413.0
ZNF155 -1397.0
ZNF37A -1387.0
TRIM33 -1385.0
MAMLD1 -1361.0
ZNF133 -1328.0
ZNF233 -1320.0
WDR61 -1268.0
EHMT2 -1260.0
PRKAG2 -1248.0
NUP50 -1242.0
ZNF189 -1236.0
SCO1 -1188.0
KMT2E -1148.0
ZNF667 -1141.0
PRKAA1 -1137.0
NCBP1 -1125.0
PPARGC1A -1095.0
PSME4 -1087.0
SERPINE1 -1083.0
YAF2 -1080.0
OCLN -1071.0
CNOT1 -1042.0
ZNF71 -1004.0
EIF4A3 -915.0
TNRC6B -914.0
ZNF565 -886.0
AIFM2 -878.0
ZNF443 -858.0
PLK2 -850.0
ZNF143 -844.0
ZKSCAN1 -838.0
CCNT2 -837.0
TTC5 -814.0
ZNF429 -798.0
BRD7 -791.0
CITED4 -784.0
ZNF442 -776.0
ZNF669 -756.0
SREBF1 -751.0
RING1 -731.0
POMC -667.0
DDIT4 -654.0
DDX39A -651.0
GTF2H5 -649.0
YWHAZ -647.0
AGRP -618.0
TGFB1 -615.0
CTSV -594.0
ZNF641 -585.0
NELFA -564.0
MED7 -535.0
BARD1 -534.0
SKP2 -520.0
CNOT2 -518.0
INTS6 -508.0
SNAPC5 -494.0
ZNF717 -493.0
ZNF764 -478.0
RBM14 -432.0
ING2 -428.0
TAF7 -389.0
PSMB10 -372.0
RPAP2 -348.0
BIRC5 -333.0
TFAP2E -328.0
MED4 -312.0
GTF3C3 -295.0
ATXN3 -290.0
GP1BA -285.0
MAPK11 -273.0
CNOT8 -257.0
WDR33 -253.0
ZNF169 -202.0
ZNF619 -194.0
ZNF562 -175.0
ZNF747 -153.0
INTS10 -119.0
PSMA4 -118.0
E2F1 -108.0
LEO1 -87.0
ARID1B -85.0
TMEM219 -63.0
MED27 -50.0
STK11 -41.0
KLF4 -9.0
ARID2 2.0
CDC26 6.0
CDK13 32.0
BCDIN3D 100.0
ZNF382 110.0
ZNF670 122.0
ANAPC10 141.0
NUP98 175.0
ZNF778 195.0
ZNF546 201.0
PIN1 202.0
ZNF665 208.0
PSMD14 225.0
MLST8 236.0
UBE2E1 291.0
ZNF658B 296.0
SMARCB1 300.0
MED15 383.0
ZNF688 386.0
ZNF197 392.0
NUP62 395.0
MED23 403.0
INTS9 406.0
THOC6 473.0
PIP4K2C 477.0
NELFB 490.0
MT-CO1 507.0
H2BC15 524.0
TARBP2 557.0
BNIP3L 581.0
UBE2I 587.0
RTF1 595.0
USP9X 622.0
AAAS 627.0
NFYA 629.0
ZNF775 678.0
ZNF547 680.0
ZNF79 693.0
FANCC 704.0
NBN 709.0
THBS1 710.0
ZNF700 712.0
ZNF200 715.0
MT-CO2 729.0
ZNF99 738.0
ZNF703 740.0
GTF2H2 765.0
AURKB 781.0
POLR3A 782.0
TNRC6A 783.0
CDC7 815.0
PPARA 838.0
AFF4 868.0
ANAPC4 875.0
GTF3C5 878.0
U2AF2 883.0
SUDS3 907.0
ZNF655 936.0
RNGTT 940.0
ZNF720 944.0
INTS2 969.0
POLR1D 983.0
U2AF1L4 985.0
DHX38 1001.0
PSMF1 1056.0
ZNF668 1077.0
ELL2 1128.0
INTS7 1160.0
MTOR 1162.0
SIRT3 1188.0
POLR3C 1189.0
CAMK2G 1201.0
APOE 1230.0
OPRM1 1233.0
FAS 1236.0
PCGF2 1249.0
CNOT11 1260.0
MDM4 1276.0
CDC25C 1278.0
NELFCD 1287.0
COX7A2L 1305.0
ELOA 1352.0
TAF2 1359.0
CRADD 1378.0
PSMC4 1389.0
THOC7 1391.0
JUNB 1397.0
TBL1XR1 1405.0
EZH2 1417.0
RPRD1A 1459.0
SCO2 1489.0
GATAD2A 1499.0
PRELID3A 1500.0
SNW1 1506.0
MTA2 1515.0
TAF4 1523.0
PSMD7 1547.0
SUPT6H 1566.0
RNF111 1594.0
RPRD1B 1621.0
TCF12 1625.0
MED14 1629.0
CDC73 1632.0
ZNF394 1687.0
UHRF1 1701.0
GTF2A2 1705.0
ZKSCAN3 1711.0
SAP18 1724.0
ZNF215 1759.0
PRMT5 1768.0
L3MBTL1 1780.0
FZR1 1793.0
NOC2L 1827.0
POLR3K 1842.0
GTF3C1 1879.0
ITCH 1890.0
DPY30 1895.0
SAP30L 1909.0
ITGA2B 1927.0
COX4I1 1963.0
SARNP 1972.0
MED16 2006.0
YWHAB 2038.0
DDX39B 2041.0
LAMTOR3 2053.0
GATAD2B 2086.0
PAPOLA 2096.0
USP7 2097.0
KAT5 2121.0
RRM2B 2176.0
PSMC3 2182.0
ZNF586 2251.0
SAP30BP 2252.0
ZNF205 2254.0
ZKSCAN4 2263.0
ZNF354A 2274.0
GTF2H4 2296.0
UBE2S 2306.0
MAPKAP1 2319.0
HUS1 2327.0
HDAC1 2347.0
FKBP6 2430.0
HDAC6 2445.0
BRF1 2456.0
CBX8 2485.0
ZNF34 2486.0
MED26 2492.0
CDK12 2497.0
PCF11 2498.0
GSK3B 2520.0
PML 2526.0
PBRM1 2551.0
SFN 2567.0
PABPN1 2573.0
MLH1 2650.0
AGO3 2652.0
MED24 2654.0
CRCP 2663.0
GPS2 2679.0
CHEK2 2738.0
HDAC11 2741.0
ZNF195 2775.0
ZNF587 2779.0
EAF1 2783.0
RYBP 2806.0
SIN3B 2807.0
ANAPC7 2814.0
WWTR1 2858.0
PTPN11 2859.0
ITGAL 2879.0
ZNF697 2897.0
PPM1D 2954.0
H2AZ1 2960.0
TAF1C 2991.0
ZNF25 2993.0
TSC1 3041.0
KRAS 3113.0
SMURF1 3123.0
CDKN1A 3132.0
GTF3C6 3141.0
ZNF160 3152.0
GTF2B 3189.0
PPARGC1B 3227.0
ZNF839 3264.0
AURKA 3271.0
DNMT3B 3281.0
H2BC11 3290.0
CBX6 3339.0
ZNF691 3347.0
CDC40 3360.0
SUPT4H1 3363.0
ZKSCAN5 3393.0
HDAC5 3445.0
POLR2L 3450.0
PSMA1 3451.0
TAF11 3477.0
PSMC6 3483.0
SMAD2 3495.0
DDIT3 3500.0
CBX3 3505.0
EHMT1 3558.0
TAF6 3570.0
PLK3 3589.0
TDG 3593.0
HIVEP3 3609.0
SUMO1 3612.0
CLP1 3627.0
TBL1X 3644.0
CDK8 3675.0
RBX1 3691.0
CCNE2 3704.0
PSMB4 3707.0
ZNF613 3710.0
INTS12 3720.0
U2AF1 3739.0
IPO8 3765.0
PSMD13 3770.0
H2BC17 3795.0
ZNF611 3811.0
INTS8 3812.0
SNRPG 3835.0
BGLAP 3845.0
ZFP69B 3903.0
ZNF750 3921.0
COX5A 3965.0
AGO2 3966.0
CDK9 4027.0
ZNF124 4029.0
ABL1 4039.0
RXRB 4044.0
NPPA 4111.0
ZNF490 4115.0
ZNF660 4122.0
VEGFA 4174.0
PSMD3 4177.0
SURF1 4179.0
PIWIL4 4197.0
GAD2 4204.0
ZNF713 4209.0
CNOT6 4214.0
PPM1A 4215.0
BANP 4218.0
H2BC4 4239.0
PSMA6 4263.0
PAF1 4267.0
CSNK2A2 4323.0
CASP10 4326.0
TFDP1 4357.0
ZNF471 4388.0
TAF8 4424.0
H2BC5 4435.0
RHEB 4447.0
PSMC2 4457.0
ANAPC11 4464.0
ZNF589 4465.0
SYMPK 4502.0
CDKN2A 4560.0
CPSF2 4583.0
RABGGTA 4589.0
PPP2R1A 4593.0
SSU72 4600.0
RMI2 4605.0
AR 4651.0
TSC2 4664.0
GPI 4667.0
SNAPC4 4669.0
PSMB2 4680.0
MOBP 4702.0
NR1I3 4742.0
CBX4 4754.0
ZKSCAN7 4766.0
ZNF556 4798.0
KMT2C 4799.0
CPSF1 4828.0
RFC2 4835.0
CPSF7 4872.0
ZNF718 4873.0
UBC 4874.0
PPP2CA 4882.0
CDK7 4908.0
TJP1 4924.0
GPRIN1 4940.0
FOXO4 4965.0
ZNF701 4975.0
RRAGD 5007.0
MED12 5009.0
RAE1 5040.0
TNFRSF10C 5056.0
SNAPC3 5115.0
DDB2 5186.0
HIPK1 5208.0
BRCA1 5214.0
ELL 5225.0
CCNK 5228.0
POLR2E 5238.0
GTF2F2 5263.0
PPP2CB 5377.0
LBR 5389.0
AKT2 5390.0
ERCC3 5421.0
PSMB8 5433.0
E2F4 5439.0
HDAC7 5441.0
NR1H3 5458.0
PSMD8 5474.0
INTS1 5484.0
GTF2F1 5494.0
MDM2 5532.0
PSMD2 5544.0
CREBBP 5593.0
HDAC10 5634.0
ZNF555 5649.0
ZNF282 5652.0
KMT2B 5686.0
POLR2G 5695.0
PSMD12 5714.0
POLR2F 5738.0
ZNF460 5743.0
PDPK1 5768.0
PSMC1 5778.0
SLC38A9 5807.0
COX7B 5839.0
NCOR1 5849.0
KCTD1 5860.0
SMARCA4 5879.0
NRBP1 5881.0
RBBP8 5902.0
PRDX1 5934.0
TP53INP1 6003.0
APAF1 6024.0
PSMD5 6029.0
SMARCC2 6070.0
H2BC12 6101.0
AKT1 6133.0
TP53BP2 6140.0
H2BC21 6180.0
ZNF347 6193.0
NDUFA4 6226.0
KCTD6 6231.0
CASP1 6238.0
GPX2 6305.0
NABP2 6310.0
CSTF3 6324.0
PSMD1 6354.0
POLR2A 6387.0
UBE2D3 6400.0
TEAD2 6420.0
GCK 6443.0
ZNF716 6445.0
POU2F2 6515.0
MBD2 6516.0
SAP130 6559.0
CSNK2B 6563.0
PSME3 6605.0
H3C15 6611.5
CPSF3 6658.0
ZNF468 6661.0
GTF2E2 6705.0
ZNF20 6712.0
EAF2 6757.0
FOXO3 6773.0
COX6A1 6782.0
SEC13 6793.0
SKIL 6805.0
PHF19 6825.0
SETD1B 6834.0
TNFRSF10D 6836.0
ZNF267 6837.0
KDM5B 6861.0
ELF2 6980.0
NOTCH1 6982.0
ASH2L 6997.0
RMI1 7005.0
SMARCD2 7040.0
SESN2 7055.0
PSMD11 7057.0
SRSF4 7078.0
CASC3 7085.0
PRKCB 7102.0
CCNH 7145.0
NRBF2 7187.0
TIGAR 7200.0
CTDP1 7209.0
PRKAG1 7316.0
PTEN 7321.0
MAML1 7341.0
ZFHX3 7416.0
POU2F1 7429.0
TAF13 7430.0
ZNF385A 7452.0
NFIA 7464.0
LAMTOR4 7482.0
HDAC3 7484.0
CTSK 7494.0
ELOB 7511.0
LSM10 7576.0
ZNF552 7580.0
TCF7L1 7623.0
H3-3A 7624.0
NUP58 7628.0
IRAK1 7649.0
LAMTOR5 7659.0
ELOC 7671.0
TNFRSF10B 7686.0
COX5B 7706.0
SEM1 7739.0
BAZ2A 7775.0
MED20 7833.0
HTT 7856.0
JAG1 7859.0
GATA1 7928.0
PSMB7 7941.0
BCL2L11 7982.0
POLR2J 7983.0
CSNK2A1 7984.0
IWS1 7996.0
JARID2 8008.0
SP1 8056.0
HIPK2 8076.0
CCNG2 8083.0
RRAGA 8084.0
KMT2D 8117.0
CTNNB1 8119.0
YWHAH 8129.0
MED8 8164.0
ERCC2 8166.0
NELFE 8177.0
SNAPC2 8214.0
TXNRD1 8216.0
ZNF18 8241.0
NDRG1 8350.0
ZNF445 8376.0
CITED2 8389.0
ZNF774 8392.0
CNOT3 8403.0
ZNF333 8425.0
ARID1A 8458.0
ZNF230 8483.0
NR6A1 8487.0
NOTCH2 8499.0
HES1 8540.0
SOD2 8563.0
SMARCD3 8576.0
YWHAE 8584.0
PSMB5 8625.0
TXN 8653.0
TAF12 8666.0
PRDX5 8681.0
RAD9B 8706.0
BID 8709.0
PSMA7 8719.0
PSMD6 8745.0
H2AC20 8783.0
EP300 8816.0
MED25 8855.0
SAP30 8863.0
TWIST2 8906.0
TOP3A 8956.0
PSMD9 9005.0
G6PC 9009.0
ZNF320 9036.0
PRKAB1 9059.0
BAX 9079.0
RUNX1 9132.0
ELL3 9173.0
PINK1 9176.0
UBE2D1 9204.0
MLLT1 9219.0
AGO1 9230.0
SRSF9 9246.0
CDKN2B 9248.0
PSMB6 9262.0
LGALS3 9294.0
ABCA6 9306.0
LAMTOR2 9311.0
NEDD4L 9328.0
TET2 9332.0
COX8A 9349.0
ARID3A 9384.0
NR1H2 9385.0
CAT 9425.0
ZNF28 9436.0
CCND3 9462.0
PRELID1 9513.0
PLAGL1 9550.0
ZNF746 9581.0
COX6B1 9596.0
TET3 9597.0
MAPK3 9636.0
SLC2A3 9751.0
PTPN1 9752.0
RB1 9765.0
HDAC8 9800.0
LAMTOR1 9855.0
RBPJ 9875.0
YWHAG 9892.0
PSMB3 9902.0
ANAPC15 9931.0
TGFA 9932.0
POLDIP3 10060.0
KCTD15 10061.0
THOC5 10063.0
AGO4 10068.0
TAF10 10093.0
NUP214 10124.0
ZNF213 10151.0
ITGA5 10158.0
KMT5A 10179.0
MAP2K6 10292.0
CARM1 10294.0
PSMD4 10295.0
RXRA 10309.0
DICER1 10324.0
SMAD6 10368.0
GADD45A 10397.0
ACTB 10419.0
HDAC4 10451.0
MAPK14 10466.0
MAML3 10499.0
RETN 10519.0
NABP1 10524.0
SATB2 10563.0
SOCS3 10637.0
LMO2 10663.0
FKBP5 10739.0
CSF1R 10769.0
GSR 10772.0
ESRRA 10775.0
DLX6 10792.0
NFIC 10795.0
STEAP3 10803.0
MAPK1 10847.0
INTS3 10878.0
G6PD 10938.0
CEBPB 11028.0
NFE2 11043.0
ZNF702P 11119.0
PHC2 11185.0
NFYC 11209.0
CTSL 11213.0
RARA 11226.0
ZNF710 11316.0
NLRC4 11341.0
NCOR2 11380.0
CDK5 11415.0
CR1 11436.0
NOTCH4 11483.0
SPI1 11522.0
BCL6 11526.0
RNU1-1 11559.5
PRKACA 11578.0
H2AJ 11606.0
PPARG 11631.0
TDRD9 11645.0
VDR 11663.0
TCF7L2 11692.0
SMAD1 11709.0
TP53I3 11719.0
NOTCH3 11733.0


Influenza Infection

Influenza Infection
526
set Influenza Infection
setSize 154
pANOVA 5.85e-27
s.dist -0.501
p.adjustANOVA 3.8e-25



Top enriched genes

Top 20 genes
GeneID Gene Rank
IPO5 -9839
NDC1 -9817
RPL3 -9701
RPS2 -9635
NUP35 -9626
NUP88 -9430
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
PARP1 -9133
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
NUP107 -8801
SEH1L -8792
RPL21 -8773

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IPO5 -9839
NDC1 -9817
RPL3 -9701
RPS2 -9635
NUP35 -9626
NUP88 -9430
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
PARP1 -9133
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
NUP107 -8801
SEH1L -8792
RPL21 -8773
RPS27A -8722
NUP160 -8699
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
RPS14 -8337
RPS23 -8334
RPL10 -8318
RPS27 -8260
RPLP2 -8255
POLR2D -8160
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
RPL22L1 -7828
NUP43 -7792
RPL30 -7783
RPL18 -7781
RPL35 -7710
RPL26 -7648
RPS4X -7636
NUP155 -7633
RPS10 -7629
RPL24 -7626
RPS16 -7617
RPL18A -7609
RAN -7577
KPNA5 -7556
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
RPL7A -7296
NUP188 -7295
RPS18 -7288
RPS8 -7161
RPS17 -7134
NUP205 -7051
RPL19 -7006
RPL23 -6933
ISG15 -6814
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPL37 -6660
RPL38 -6589
RPS28 -6429
RPL36 -6343
RPL8 -6274
POM121C -6074
RPL27 -6068
RPL41 -6065
RPL39 -5790
NUP133 -5674
RPS19 -5616
SLC25A6 -5581
RPL13 -5550
RPS26 -5524
RPS15 -5342
NUP54 -5340
RPS24 -5310
POLR2B -5111
HSP90AA1 -5083
RPL37A -4774
RPSA -4559
NUP153 -4433
NUP210 -4373
KPNA1 -4278
KPNA3 -4263
XPO1 -4204
RPL36AL -4148
TPR -4127
POLR2K -3902
RPLP1 -3887
KPNA2 -3851
POLR2H -3611
NUP93 -3163
GRSF1 -3125
RANBP2 -3109
NUP42 -2718
POLR2C -2566
CPSF4 -2319
POM121 -2295
RPL28 -1952
NUP85 -1717
POLR2I -1599
UBA52 -1437
NUP37 -1424
CANX -1278
NUP50 -1242
FAU -1029
KPNA4 -701
TGFB1 -615
KPNB1 -109
RPL39L -69
NUP98 175
NUP62 395
EIF2AK2 426
AAAS 627
RPS4Y1 1461
RPS9 2392
PABPN1 2573
RPS27L 2784
POLR2L 3450
CALR 4966
RAE1 5040
POLR2E 5238
GTF2F2 5263
GTF2F1 5494
POLR2G 5695
RPL3L 5700
POLR2F 5738
RPL26L1 6187
POLR2A 6387
HSPA1A 6708
SEC13 6793
NUP58 7628
CLTA 7680
POLR2J 7983
DNAJC3 8291
CLTC 9346
NUP214 10124


Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
742
set Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
setSize 114
pANOVA 1.01e-25
s.dist -0.568
p.adjustANOVA 5.96e-24



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498
RPL34 -8489

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
RPS14 -8337
GSPT2 -8336
RPS23 -8334
RPL10 -8318
RPS27 -8260
RPLP2 -8255
NCBP2 -8212
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
UPF3A -7835
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
RPS16 -7617
RPL18A -7609
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
DCP1A -7356
RPL7A -7296
RPS18 -7288
RPS8 -7161
RPS17 -7134
RNPS1 -7032
RPL19 -7006
RPL23 -6933
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPL37 -6660
RPL38 -6589
GSPT1 -6576
RPS28 -6429
RPL36 -6343
RPL8 -6274
RPL27 -6068
RPL41 -6065
RPL39 -5790
RPS19 -5616
RPL13 -5550
RPS26 -5524
RPS15 -5342
RPS24 -5310
PNRC2 -5116
RPL37A -4774
RPSA -4559
SMG6 -4443
RPL36AL -4148
MAGOHB -4045
RPLP1 -3887
PABPC1 -3482
UPF3B -3065
RBM8A -2980
RPL28 -1952
MAGOH -1931
SMG5 -1876
SMG1 -1661
UBA52 -1437
PPP2R2A -1333
NCBP1 -1125
FAU -1029
EIF4A3 -915
UPF2 -229
RPL39L -69
SMG8 663
RPS4Y1 1461
RPS9 2392
RPS27L 2784
ETF1 4300
PPP2R1A 4593
PPP2CA 4882
RPL3L 5700
RPL26L1 6187
UPF1 6979
CASC3 7085
SMG9 9218
SMG7 9427
EIF4G1 9922


Nonsense-Mediated Decay (NMD)

Nonsense-Mediated Decay (NMD)
744
set Nonsense-Mediated Decay (NMD)
setSize 114
pANOVA 1.01e-25
s.dist -0.568
p.adjustANOVA 5.96e-24



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498
RPL34 -8489

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
RPS14 -8337
GSPT2 -8336
RPS23 -8334
RPL10 -8318
RPS27 -8260
RPLP2 -8255
NCBP2 -8212
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
UPF3A -7835
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
RPS16 -7617
RPL18A -7609
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
DCP1A -7356
RPL7A -7296
RPS18 -7288
RPS8 -7161
RPS17 -7134
RNPS1 -7032
RPL19 -7006
RPL23 -6933
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPL37 -6660
RPL38 -6589
GSPT1 -6576
RPS28 -6429
RPL36 -6343
RPL8 -6274
RPL27 -6068
RPL41 -6065
RPL39 -5790
RPS19 -5616
RPL13 -5550
RPS26 -5524
RPS15 -5342
RPS24 -5310
PNRC2 -5116
RPL37A -4774
RPSA -4559
SMG6 -4443
RPL36AL -4148
MAGOHB -4045
RPLP1 -3887
PABPC1 -3482
UPF3B -3065
RBM8A -2980
RPL28 -1952
MAGOH -1931
SMG5 -1876
SMG1 -1661
UBA52 -1437
PPP2R2A -1333
NCBP1 -1125
FAU -1029
EIF4A3 -915
UPF2 -229
RPL39L -69
SMG8 663
RPS4Y1 1461
RPS9 2392
RPS27L 2784
ETF1 4300
PPP2R1A 4593
PPP2CA 4882
RPL3L 5700
RPL26L1 6187
UPF1 6979
CASC3 7085
SMG9 9218
SMG7 9427
EIF4G1 9922


Innate Immune System

Innate Immune System
535
set Innate Immune System
setSize 966
pANOVA 2.58e-25
s.dist 0.197
p.adjustANOVA 1.47e-23



Top enriched genes

Top 20 genes
GeneID Gene Rank
LILRB2 11743
SLC11A1 11742
P2RX1 11737
OSCAR 11726
C1QB 11723
MAPKAPK3 11720
DOK3 11717
NCSTN 11715
TCIRG1 11708
HK3 11695
C1QC 11693
DNASE1L1 11691
SERPINA1 11685
ANPEP 11677
MAP3K8 11646
C3AR1 11629
MYD88 11614
FGR 11610
SIRPA 11601
GNS 11592

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
LILRB2 11743
SLC11A1 11742
P2RX1 11737
OSCAR 11726
C1QB 11723
MAPKAPK3 11720
DOK3 11717
NCSTN 11715
TCIRG1 11708
HK3 11695
C1QC 11693
DNASE1L1 11691
SERPINA1 11685
ANPEP 11677
MAP3K8 11646
C3AR1 11629
MYD88 11614
FGR 11610
SIRPA 11601
GNS 11592
ITGAX 11581
PRKACA 11578
ACAA1 11576
C2 11573
HP 11572
IDH1 11571
RASGRP4 11568
CD63 11550
QSOX1 11547
RNASE2 11535
WASF1 11510
PRKCD 11506
FCER1G 11505
NOD2 11501
SIGLEC9 11493
MOSPD2 11479
LAIR1 11472
ATP6V0A1 11467
CD300E 11454
C1QA 11453
CTSD 11452
RNF135 11446
CTSB 11445
CR1 11436
GUSB 11435
S100A9 11432
SIGLEC16 11421
HCK 11416
ASAH1 11411
NEU1 11402
NCKAP1L 11401
AGPAT2 11396
BTK 11379
CD36 11354
RIPK3 11344
NLRC4 11341
TNFAIP6 11338
IMPDH1 11335
VNN1 11333
ALDH3B1 11330
FPR1 11322
TIMP2 11318
S100A8 11315
PECAM1 11314
MCEMP1 11306
PGAM1 11305
ITGAM 11288
BRI3 11285
ATP6V0D1 11283
NKIRAS2 11282
PLAC8 11276
UNC13D 11268
FCGR1A 11256
PTPN6 11254
WAS 11238
GM2A 11237
CTSL 11213
ARPC1A 11206
CASP9 11191
NFAM1 11188
MYO10 11182
MYO9B 11181
CDA 11180
ANXA2 11174
IRAK3 11172
TRPM2 11170
ALOX5 11153
MEFV 11122
CYFIP1 11117
C5AR1 11109
CD177 11101
PYCARD 11094
GRN 11084
S100A11 11078
S100A12 11077
GLA 11064
LTA4H 11060
C4BPA 11057
FCGR3A 11056
CRISPLD2 11052
VAT1 11042
NCF2 11041
PELI3 11036
CFB 11024
TNFRSF1B 11022
UNC93B1 11011
COTL1 11009
TLR5 10992
STAT6 10986
CD68 10980
PLEKHO2 10971
ITGB2 10970
NLRX1 10967
ARPC1B 10956
RPS6KA1 10944
ALDOA 10937
SERPINB1 10935
GRB2 10925
CSTB 10924
ALPK1 10916
TOM1 10915
RAC1 10907
RAB10 10903
TRIM25 10901
LYN 10893
PADI2 10877
NCF4 10873
PSEN1 10871
ATP6V0C 10858
MAPK1 10847
GLB1 10846
PSTPIP1 10845
PLAUR 10834
TEC 10815
CD93 10813
TLR8 10804
FPR2 10794
LAT2 10791
PYGL 10789
ATP11A 10784
CTSZ 10773
TLR2 10761
PTAFR 10758
TYROBP 10755
GCA 10753
CD55 10741
PAK1 10704
NBEAL2 10699
ARHGAP9 10674
CD300A 10650
MMP25 10645
NAPRT 10642
RHOG 10634
CYBA 10617
RAB24 10600
TSPAN14 10591
CLU 10561
SIGLEC15 10557
C5AR2 10548
PKM 10547
LILRB3 10546
CD14 10542
PLD1 10520
RETN 10519
CTSA 10517
CEACAM3 10514
CPPED1 10512
ATP6V0B 10507
MAPK14 10466
ALAD 10444
ADGRG3 10443
AP2A2 10434
BIN2 10421
ACTB 10419
QPCT 10407
ARSB 10406
CLEC6A 10404
STK11IP 10391
PLCG2 10376
PLD2 10367
FCGR2A 10355
FTL 10348
MAPK7 10339
MMP9 10322
PSMD4 10295
MAP2K6 10292
GYG1 10290
HPSE 10288
BST1 10273
WASF2 10259
CD53 10254
MAP2K1 10244
CAPN1 10238
DOCK2 10229
GAB2 10228
RAB4B 10224
MAPK10 10215
RAB5C 10197
CYBB 10196
GPR84 10194
RAB3D 10172
VAV1 10149
AP1M1 10145
CKAP4 10088
SYK 10086
IGF2R 10077
MGST1 10069
ARPC5 10048
CD58 10047
RAB31 10045
PSAP 10019
LY96 10002
CFP 9950
HSPA6 9912
PSMB3 9902
DNAJC5 9897
GSN 9887
LAMTOR1 9855
ELMO2 9846
RAF1 9820
CYB5R3 9808
IGKV1-39 9771
MAP2K3 9766
MGAM 9760
GALNS 9756
SLC2A3 9751
DNM2 9736
PDAP1 9730
ATP6V1D 9706
ATP6V1B2 9701
SLC15A4 9689
CFL1 9683
CLEC4D 9682
ADGRE5 9681
CARD9 9678
DERA 9675
UBA3 9647
ACLY 9642
DNAJC13 9641
MYO5A 9640
TICAM1 9637
MAPK3 9636
ARSA 9608
DBNL 9555
GMFG 9547
PGM2 9542
SDCBP 9536
LRG1 9534
CTSC 9524
CCR2 9487
ARPC3 9484
CYSTM1 9471
S100P 9448
PTPRJ 9428
CAT 9425
AMPD3 9412
CRK 9373
TLR4 9355
CD33 9340
MNDA 9331
FOLR3 9323
LAMTOR2 9311
RAB7A 9295
LGALS3 9294
PRKCE 9268
PSMB6 9262
LIMK1 9261
TMBIM1 9252
ARL8A 9235
ARPC4 9223
ARPC2 9212
SERPINB6 9209
UBE2D1 9204
FCN1 9194
VPS35L 9180
MVP 9155
P2RX7 9153
ADAM10 9130
DTX4 9053
DUSP3 9049
ARG1 9013
FCAR 9011
PSMD9 9005
COMMD9 9004
IQGAP1 8998
IKBKG 8902
IQGAP2 8896
NLRP3 8894
TRAPPC1 8880
SELL 8826
EP300 8816
ATP6V1C1 8809
RNASET2 8806
RHOA 8752
TLR1 8749
MEF2A 8747
PSMD6 8745
PSMA7 8719
TXN 8653
IKBKE 8629
IRF7 8626
PSMB5 8625
TANK 8608
LAMP1 8606
PNP 8604
SNAP29 8589
ACTG1 8547
DOCK1 8538
ATP6V1A 8486
CD44 8470
CAP1 8422
ATP6V0E1 8302
DNAJC3 8291
GAA 8265
PGLYRP2 8211
CLEC4E 8196
LRRFIP1 8161
VAPA 8135
CTNNB1 8119
ITGAV 8115
CNPY3 8102
MANBA 8050
TRIM21 8042
CAPZA1 8032
MUC1 8020
CAPZA2 7999
PSMB7 7941
SHC1 7938
RAB27A 7933
CLEC4A 7903
DYNC1LI1 7881
NCKAP1 7871
CREG1 7822
TOLLIP 7802
SEM1 7739
TREM1 7737
AGER 7730
MUC6 7695
NOS1 7676
CANT1 7672
CDC34 7669
CMTM6 7664
ABI1 7663
PDXK 7660
IST1 7650
IRAK1 7649
TLR6 7631
ATP6V1E1 7588
RAB6A 7579
PRCP 7572
NPC2 7560
PTPRC 7546
CD46 7504
CTSK 7494
DYNLT1 7489
NCF1 7481
VAV2 7476
DDOST 7465
NFKBIB 7438
METTL7A 7399
PANX1 7397
KCNAB2 7393
LAMP2 7357
ACTR2 7352
CDC42 7337
STK10 7292
MAPK13 7251
CTSS 7190
CHUK 7179
IGLV7-43 7123
MUC16 7106
PSMD11 7057
NHLRC3 7045
SIRPB1 7036
RELB 7028
RAP1A 7021
ROCK1 7020
HEXB 6925
TNIP2 6869
TIRAP 6862
NDUFC2 6785
CTSH 6758
MAN2B1 6709
HSPA1A 6708
WIPF2 6706
ITLN1 6703
MUC5B 6697
SOCS1 6664
ACTR3 6644
VRK3 6628
PSME3 6605
OSTF1 6599
ATOX1 6597
TUBB4B 6583
CSNK2B 6563
YPEL5 6553
PIGR 6544
FUCA2 6509
FUCA1 6504
MAPKAPK2 6495
NFASC 6488
FABP5 6480
PLD3 6403
UBE2D3 6400
FTH1 6366
PSMD1 6354
MYH9 6290
PIK3R2 6269
SIGLEC5 6250
CASP1 6238
COPB1 6181
ITPR2 6136
CLEC7A 6117
PIK3CB 6109
ATG7 6077
CASP4 6041
PSMD5 6029
APAF1 6024
CXCR1 6006
ADAM8 5994
PRDX4 5952
MAVS 5950
CAB39 5909
DNM1 5834
PAK2 5789
GLIPR1 5779
PSMC1 5778
PDPK1 5768
CLEC5A 5765
POLR2F 5738
FADD 5721
PSMD12 5714
PRKCSH 5698
RNASE6 5684
HEBP2 5680
VAV3 5645
CREBBP 5593
TICAM2 5572
PSMD2 5544
TBK1 5538
C4B 5483
PSMD8 5474
DGAT1 5440
PSMB8 5433
TKFC 5424
PPP2CB 5377
RAP1B 5363
ICAM3 5285
GDI2 5257
POLR2E 5238
LPCAT1 5222
IKBKB 5156
ATP6V1F 5145
SURF4 5135
CNN2 5113
B4GALT1 5109
TAB3 5102
RAC2 5082
RAP2C 5053
ATP6V1H 5047
SRP14 5005
RAB5B 4935
PPP2CA 4882
UBC 4874
C5 4786
PGM1 4743
PSMB2 4680
GPI 4667
TARM1 4634
ATP11B 4630
PPP2R1A 4593
MAP3K1 4584
MAP2K4 4579
ORM2 4551
TMEM30A 4528
PSMC2 4457
APEH 4454
CGAS 4448
HSPA1B 4429
C1R 4413
OTUD5 4370
RAB18 4366
SNAP23 4343
CASP10 4326
CEACAM1 4318
GSDMD 4284
VCP 4271
PSMA6 4263
VAMP8 4250
FRK 4243
ACTR10 4228
PSMD3 4177
FAF2 4132
AHCYL1 4099
BCL10 4090
KCMF1 4047
ABL1 4039
ATF1 4020
PDZD11 3960
CD300LB 3957
NFKBIA 3946
UBE2M 3919
SERPINB10 3849
LY86 3800
HVCN1 3781
IGKV1D-39 3771
PSMD13 3770
LEAP2 3767
PSMB4 3707
IGLV2-11 3601
CST3 3572
PSMC6 3483
ORM1 3469
PSMA1 3451
POLR2L 3450
STOM 3437
TAX1BP1 3407
APP 3315
PELI2 3259
VTN 3250
DYNLL1 3185
GHDC 3169
HLA-C 3114
KRAS 3113
CLEC4C 3103
SLCO4C1 3100
ECSIT 3063
IGKV5-2 3051
ERP44 2957
RAB14 2942
NLRC5 2931
ITGAL 2879
PTPN11 2859
UBR4 2841
C1S 2813
UBE2K 2757
MAP3K7 2721
GGH 2692
CRCP 2663
DDX41 2607
DSP 2606
CLEC12A 2566
PPP2R5D 2555
ATP7A 2494
EPPIN 2443
PLAU 2369
PPP3CB 2367
DIAPH1 2357
PAFAH1B2 2356
HTN1 2343
HLA-B 2308
CPN2 2284
CFD 2249
IFI16 2208
PSMC3 2182
TAB1 2158
LAMTOR3 2053
LPO 2037
PGLYRP1 1994
ATP6AP2 1907
C3 1898
ITCH 1890
PELI1 1876
AIM2 1862
POLR3K 1842
NRAS 1826
C4A 1786
GSTP1 1776
MAPK12 1731
COMMD3 1730
ATP8B4 1600
PSMD7 1547
TREX1 1531
UBA7 1496
CXCR2 1488
PSMC4 1389
A1BG 1362
NF2 1346
NFKB2 1272
IGLV2-23 1244
RAB3A 1226
FBXW11 1218
VCL 1210
POLR3C 1189
PFKL 1186
MAP2K7 1099
PSMF1 1056
RNASE3 1013
RAP2B 1004
TMEM179B 986
POLR1D 983
BST2 980
S100A1 892
C6orf120 822
POLR3A 782
RIPK2 769
PLPP5 750
NOD1 699
RIPK1 553
LCP2 514
MMP8 336
PPP3R1 308
C8G 292
PSMD14 225
PIN1 202
ARMC8 184
SIGLEC14 129
MAGT1 71
CXCL1 35
SLC44A2 34
CDK13 32
OLFM4 -31
ANO6 -52
HBB -79
KPNB1 -109
PSMA4 -118
CPNE3 -215
SUGT1 -227
DNM3 -250
CCT8 -260
MAPK11 -273
IGLV10-54 -276
BCL2L1 -300
IGKV3D-20 -305
MASP2 -330
PSMB10 -372
DEGS1 -381
MUC12 -387
NME2 -399
IGLC3 -403
PPP3CA -429
STBD1 -458
STING1 -472
PAK3 -533
CTSV -594
IGKV2D-28 -728
LRRC7 -743
IGHG4 -760
LYZ -787
PRDX6 -823
PROS1 -948
SLPI -957
PTX3 -1006
DYNC1H1 -1040
MUCL1 -1043
EEA1 -1079
PSME4 -1087
IGLV1-44 -1090
PIK3CA -1131
CPNE1 -1135
ADGRE3 -1159
BAIAP2 -1231
HLA-H -1311
DEFA1 -1338
TRAF6 -1353
CRACR2A -1363
WASL -1370
TNFAIP3 -1377
CLEC10A -1396
ELMO1 -1412
UBA52 -1437
JUN -1440
IGHG1 -1504
C4BPB -1592
IGHV3-13 -1600
DDX3X -1650
HUWE1 -1658
DEFA3 -1715
RPS6KA2 -1720
MME -1743
BIRC2 -1798
NLRP1 -1858
PTPRB -1899
EPX -1916
IGLV3-25 -1935
PSMB1 -1960
BRK1 -2011
PSMA2 -2032
TLR9 -2033
JUP -2056
ATP6V1C2 -2065
POLR3GL -2090
SYNGR1 -2163
NFKB1 -2166
PCBP2 -2170
IGLV1-36 -2214
IGHV4-59 -2340
PI3 -2357
AGL -2364
PTPRN2 -2372
UBB -2442
HLA-E -2458
XRCC5 -2484
RELA -2563
FCGR3B -2630
DUSP4 -2651
CHIT1 -2666
UBE2D2 -2828
TRIM56 -2840
MYO1C -2881
PPP2R1B -2904
IGKV1-17 -2929
IGKV2-30 -2958
IGLV1-40 -3024
PYGB -3068
CASP2 -3098
IGHG2 -3113
HRAS -3116
SLC2A5 -3147
IRF3 -3150
UBE2N -3154
DUSP6 -3175
DUSP7 -3183
CD59 -3215
DEFA4 -3234
DHX58 -3255
SOS1 -3263
PIK3C3 -3291
IGLV4-69 -3305
AAMP -3318
PTGES2 -3328
PTK2 -3332
DSN1 -3386
UBE2V1 -3427
TIFA -3429
RPS6KA3 -3451
HRNR -3513
TAB2 -3529
WIPF1 -3530
IGHV1-46 -3558
PSME2 -3570
HGSNAT -3596
POLR2H -3611
IGHV3-11 -3626
MLEC -3628
S100B -3661
AOC1 -3663
CREB1 -3751
PGRMC1 -3760
CD209 -3788
MEF2C -3791
ITPR1 -3809
FOS -3812
POLR2K -3902
CD19 -3919
DHX36 -3988
FGL2 -4013
ILF2 -4055
IGHG3 -4128
DPP7 -4153
KIR2DS4 -4195
TXNDC5 -4205
IGHV2-70 -4223
IGLC1 -4280
IGKV2-28 -4281
PSMA3 -4338
IGKV1-12 -4392
PIK3R4 -4411
TLR7 -4434
ATP6V1G1 -4463
IGLV1-47 -4485
HSP90B1 -4493
TXNIP -4515
NFATC1 -4523
RBSN -4545
PPIA -4561
PSMD10 -4578
RAB9B -4668
RASGRP2 -4683
IGHV3-30 -4685
TMC6 -4698
GOLGA7 -4761
CYFIP2 -4772
CD180 -4809
CD81 -4851
SIKE1 -4878
CD4 -4882
IGHV4-39 -4884
LCN2 -4914
KLRC2 -4927
ATP6V0A2 -4935
ATF2 -4941
IGKV1-33 -4953
MRE11 -4960
POLR3B -4975
ACTR1B -5027
PPIE -5064
IGKV3-20 -5082
HSP90AA1 -5083
CEACAM6 -5119
IGLC2 -5138
CALM1 -5150
TRAF3 -5198
CASP8 -5208
ENPP4 -5217
PLA2G6 -5218
IGHV3-7 -5228
IGKC -5232
PRKDC -5261
TUBB -5289
IGLV1-51 -5296
ATG5 -5297
HLA-A -5456
CRISP3 -5472
IGHV1-2 -5526
SRC -5527
PA2G4 -5544
CHI3L1 -5551
DHX9 -5556
ATG12 -5591
IGLV8-61 -5601
SIGIRR -5612
IGHV3-23 -5636
IGLV3-27 -5637
YES1 -5662
CTSG -5681
PPBP -5719
ITPR3 -5727
IGLC7 -5764
SKP1 -5791
IFIH1 -5792
RAB44 -5839
ATP6V1E2 -5845
IGHV3-48 -5881
PSMC5 -5909
MAPK9 -5918
CR2 -5934
AGA -5943
MS4A3 -5983
ELANE -6034
ABCA13 -6063
ALDOC -6087
OLR1 -6122
IGHE -6130
ATAD3B -6192
CEP290 -6203
TCN1 -6219
GRAP2 -6236
IL1B -6271
RAB37 -6287
ZBP1 -6305
APRT -6333
PSMA5 -6362
PRTN3 -6370
PSME1 -6399
POLR3F -6436
WASF3 -6482
CEACAM8 -6488
LTF -6540
IGHV2-5 -6583
IGHV4-34 -6614
FYN -6619
MUC20 -6632
IRAK2 -6676
IGHV3-53 -6692
TRAF2 -6717
UBE2L6 -6722
TLR10 -6794
ISG15 -6814
MIF -6822
NOS3 -6838
BCL2 -6938
IGLV7-46 -6955
ELK1 -6971
BTRC -6984
NCKIPSD -6991
POLR3E -6993
FRMPD3 -7031
SERPING1 -7047
EEF2 -7073
BPI -7115
MAP3K14 -7171
CAND1 -7207
AZU1 -7221
RPS6KA5 -7223
TBC1D10C -7271
SLC27A2 -7272
RNF216 -7294
IGKV4-1 -7302
KRT1 -7308
B2M -7346
IGLV3-19 -7358
TMEM63A -7364
IGKV1-5 -7365
SVIP -7384
IGLV2-8 -7468
MUC4 -7504
IGLV3-12 -7540
SARM1 -7566
IGHV1-69 -7589
PSMB9 -7625
NIT2 -7632
CAMP -7637
KLRK1 -7644
SCAMP1 -7668
IGKV3-15 -7683
HMGB1 -7684
KLRD1 -7719
XRCC6 -7770
POLR1C -7797
ABI2 -7811
NKIRAS1 -7813
POLR3G -7858
GZMM -7924
HERC5 -7927
MPO -7958
ATP6V1G2 -8049
MS4A2 -8050
MAPK8 -8128
DDX58 -8149
IGLV3-1 -8150
ORMDL3 -8162
NFATC3 -8193
POLR3D -8194
CD47 -8257
IGLV3-21 -8327
IGKV1-16 -8350
ATP6V0E2 -8351
LGMN -8451
PLCG1 -8497
IGHV3-33 -8574
IGLV2-14 -8599
RPS27A -8722
IGLV2-18 -8778
NCK1 -8821
NLRC3 -8850
CUL1 -8878
IGLV5-45 -8955
IGLV6-57 -8979
RHOF -9031
CARD11 -9047
CD3G -9125
HSP90AB1 -9152
LAT -9159
HSPA8 -9166
GNLY -9182
HMOX2 -9212
ITK -9231
FCER1A -9235
TRIM32 -9302
DSC1 -9305
PIK3R1 -9306
EEF1A1 -9389
IGKV3-11 -9443
RNF125 -9466
PTPN4 -9478
CYLD -9484
LCK -9485
POLR3H -9488
TLR3 -9494
CD247 -9497
ATP8A1 -9501
SPTAN1 -9516
RASGRP1 -9519
CFH -9525
TXK -9555
PLD4 -9601
MALT1 -9614
ICAM2 -9623
PRKCQ -9643
CCT2 -9661
NFATC2 -9680
BIRC3 -9718
PRKACB -9741
IMPDH2 -9848
CCR6 -9877


Selenoamino acid metabolism

Selenoamino acid metabolism
1059
set Selenoamino acid metabolism
setSize 114
pANOVA 1.1e-24
s.dist -0.555
p.adjustANOVA 6.01e-23



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
LARS1 -8879
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
IARS1 -8710
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
LARS1 -8879
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
IARS1 -8710
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
RPS14 -8337
RPS23 -8334
RPL10 -8318
RPS27 -8260
RPLP2 -8255
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
RPL35 -7710
RPL26 -7648
KARS1 -7645
RPS4X -7636
RPS10 -7629
RPL24 -7626
RPS16 -7617
RPL18A -7609
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
RPL7A -7296
RPS18 -7288
RPS8 -7161
RPS17 -7134
SEPSECS -7064
RPL19 -7006
RPL23 -6933
EPRS1 -6849
RPS29 -6791
DARS1 -6758
RPS11 -6742
RPS21 -6706
RPL37 -6660
RPL38 -6589
RPS28 -6429
SARS1 -6425
RPL36 -6343
RPL8 -6274
SECISBP2 -6069
RPL27 -6068
RPL41 -6065
SCLY -5892
RPL39 -5790
RPS19 -5616
RPL13 -5550
RPS26 -5524
RPS15 -5342
RPS24 -5310
EEFSEC -5238
AIMP1 -5088
RPL37A -4774
RPSA -4559
RPL36AL -4148
RPLP1 -3887
PSTK -3075
QARS1 -3062
AHCY -2734
AIMP2 -2623
CTH -2211
RPL28 -1952
INMT -1946
UBA52 -1437
RARS1 -1110
FAU -1029
RPL39L -69
RPS4Y1 1461
EEF1E1 2209
RPS9 2392
RPS27L 2784
RPL3L 5700
RPL26L1 6187
SEPHS2 7242
GNMT 7343
HNMT 8194
TXNRD1 8216
PAPSS1 9661
MARS1 9700
GSR 10772
CBS 10976
PAPSS2 11736


SRP-dependent cotranslational protein targeting to membrane

SRP-dependent cotranslational protein targeting to membrane
1040
set SRP-dependent cotranslational protein targeting to membrane
setSize 111
pANOVA 1.26e-24
s.dist -0.562
p.adjustANOVA 6.59e-23



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
SRPRB -8515
RPL6 -8498

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
SRPRB -8515
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
RPS14 -8337
RPS23 -8334
RPL10 -8318
RPS27 -8260
RPLP2 -8255
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
TRAM1 -7911
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
RPS16 -7617
RPL18A -7609
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
RPL7A -7296
RPS18 -7288
RPS8 -7161
RPS17 -7134
RPL19 -7006
RPL23 -6933
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPL37 -6660
RPL38 -6589
RPS28 -6429
RPL36 -6343
RPL8 -6274
RPL27 -6068
RPL41 -6065
RPL39 -5790
RPS19 -5616
RPL13 -5550
RPS26 -5524
RPS15 -5342
RPS24 -5310
SEC11C -5303
SRP72 -4824
RPL37A -4774
RPSA -4559
SRP9 -4398
RPL36AL -4148
RPLP1 -3887
SEC61A2 -3262
SSR1 -2645
SRP68 -2562
SPCS2 -2449
SSR2 -2362
SEC61G -2328
SPCS1 -2007
RPL28 -1952
SPCS3 -1816
UBA52 -1437
FAU -1029
SSR3 -664
SRP19 -483
RPL39L -69
RPS4Y1 1461
SSR4 1961
RPS9 2392
RPS27L 2784
SEC61A1 3976
RPN1 4038
SEC61B 4523
SRP14 5005
SRPRA 5496
RPL3L 5700
RPL26L1 6187
SRP54 6468
RPN2 7108
SEC11A 7174
DDOST 7465


RNA Polymerase II Transcription

RNA Polymerase II Transcription
908
set RNA Polymerase II Transcription
setSize 1196
pANOVA 4.47e-20
s.dist -0.157
p.adjustANOVA 2.26e-18



Top enriched genes

Top 20 genes
GeneID Gene Rank
RORC -9883
KIT -9844
TCF7 -9843
NPM1 -9836
CAMK4 -9799
THOC3 -9796
GLS -9763
NR3C2 -9761
FOXO1 -9743
ZNF711 -9729
RBL2 -9700
DYRK2 -9696
ZNF33B -9689
NFATC2 -9680
PERP -9667
NFYB -9659
ZNF551 -9658
RPA1 -9657
RUNX2 -9648
PRKCQ -9643

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RORC -9883.0
KIT -9844.0
TCF7 -9843.0
NPM1 -9836.0
CAMK4 -9799.0
THOC3 -9796.0
GLS -9763.0
NR3C2 -9761.0
FOXO1 -9743.0
ZNF711 -9729.0
RBL2 -9700.0
DYRK2 -9696.0
ZNF33B -9689.0
NFATC2 -9680.0
PERP -9667.0
NFYB -9659.0
ZNF551 -9658.0
RPA1 -9657.0
RUNX2 -9648.0
PRKCQ -9643.0
ZNF420 -9642.0
PMAIP1 -9639.0
WWP1 -9624.0
SUPT16H -9598.0
FBXO32 -9595.0
ZNF530 -9593.0
RORA -9585.0
GATA3 -9575.0
LEF1 -9568.0
ZIK1 -9567.0
ZNF549 -9560.0
HSPD1 -9514.0
LRPPRC -9513.0
ZNF136 -9491.0
LSM11 -9482.0
PTPN4 -9478.0
RAD1 -9471.0
CAMK2D -9460.0
MLLT3 -9457.0
ZNF287 -9448.0
TFDP2 -9444.0
IGFBP3 -9434.0
MYC -9418.0
STAT1 -9404.0
ZNF286A -9397.0
ANAPC1 -9394.0
NR1D2 -9362.0
ZNF208 -9334.0
TNFRSF18 -9325.0
NR1D1 -9318.0
ZNF566 -9289.0
CCND2 -9246.0
GAMT -9243.0
ZNF548 -9218.0
ZNF671 -9191.0
ZNF431 -9149.0
TNRC6C -9142.0
PARP1 -9133.0
ZNF14 -9130.0
CNOT6L -9114.0
WRN -9097.0
ZNF681 -9089.0
ZNF544 -9084.0
PCGF5 -9061.0
SSRP1 -9045.0
ZNF112 -9037.0
ZC3H8 -9035.0
ZNF583 -9026.0
ZNF568 -9016.0
RGCC -9009.0
PRR5 -9001.0
ZFP28 -8997.0
ZNF416 -8970.0
RUNX3 -8952.0
FASLG -8936.0
ING5 -8935.0
SIN3A -8913.0
CUL1 -8878.0
ZNF517 -8859.0
GLI3 -8843.0
TP53RK -8827.0
FANCD2 -8817.0
PLXNA4 -8810.0
AUTS2 -8807.0
ZNF184 -8799.0
PRMT6 -8789.0
ZNF485 -8781.0
ERBB2 -8774.0
AKT3 -8761.0
EPC1 -8757.0
ZNF567 -8743.0
ZNF337 -8725.0
RPS27A -8722.0
ZNF473 -8717.0
ZNF202 -8715.0
GLS2 -8711.0
BMI1 -8707.0
RFC3 -8694.0
ZNF354C -8658.0
ZNF749 -8639.0
NUDT21 -8636.0
ZNF74 -8635.0
TP53 -8613.0
PHAX -8612.0
CNOT7 -8609.0
ZNF664 -8578.0
YEATS4 -8569.0
CDK4 -8539.0
JMY -8535.0
ZNF599 -8495.0
ZNF302 -8478.0
ZNF211 -8472.0
ZNF559 -8449.0
ZNF708 -8431.0
CCNG1 -8400.0
BRD1 -8393.0
ZFP1 -8379.0
COX11 -8355.0
PPP1R13B -8332.0
ZNF30 -8321.0
ZNF678 -8303.0
ZNF331 -8301.0
ZNF430 -8300.0
ZNF696 -8297.0
ZNF43 -8258.0
SMURF2 -8254.0
ZNF721 -8249.0
ZNF616 -8248.0
SCMH1 -8236.0
NCBP2 -8212.0
ZNF354B -8182.0
POLR2D -8160.0
ZNF727 -8137.0
ZNF253 -8107.0
GPAM -8085.0
ZNF554 -8080.0
ZNF138 -8077.0
CDC23 -8076.0
ZNF786 -8075.0
RPA3 -8069.0
BTG2 -8011.0
SRSF5 -7996.0
TRIM28 -7995.0
BLK -7991.0
TAF4B -7985.0
ZNF737 -7984.0
GTF2H3 -7969.0
ITGA4 -7966.0
KAT2A -7883.0
PVALB -7854.0
CLDN5 -7851.0
SRSF11 -7838.0
GATA2 -7834.0
ZNF675 -7824.0
ZNF792 -7822.0
ZNF263 -7806.0
ZNF257 -7772.0
RAD17 -7742.0
RFC4 -7736.0
ZNF248 -7734.0
MEAF6 -7722.0
WWOX -7721.0
ZNF707 -7688.0
SIRT1 -7685.0
PPP2R5C -7679.0
KRBOX4 -7673.0
PRMT1 -7660.0
E2F6 -7656.0
PRDM1 -7655.0
ZNF571 -7638.0
PSMB9 -7625.0
HDAC9 -7621.0
ICE2 -7543.0
ZNF3 -7533.0
NR2C2AP -7518.0
INTS5 -7514.0
ATM -7513.0
ZSCAN25 -7509.0
CDKN1B -7508.0
MED10 -7505.0
ZNF519 -7492.0
FYTTD1 -7487.0
ZNF614 -7476.0
TCEA1 -7475.0
TGIF2 -7440.0
PIP4K2B -7436.0
ZNF101 -7429.0
ZNF597 -7426.0
CASP6 -7413.0
ZNF649 -7409.0
MSH2 -7399.0
ZNF432 -7398.0
ZNF570 -7391.0
CSTF1 -7377.0
SMARCC1 -7357.0
PPARD -7353.0
ZNF446 -7335.0
MAML2 -7323.0
RBBP7 -7322.0
ZNF773 -7319.0
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ZNF680 -5733.0
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ZNF70 -4112.0
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ZNF689 -3443.0
ZNF770 -3413.0
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ZNF496 -3117.0
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ZNF738 -2974.0
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ZNF785 -2631.0
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ZNF791 -2598.0
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ZNF577 -2545.0
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ZNF625 -2189.0
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FBXW7 -1985.0
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ZNF558 -1914.0
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ZNF41 -1759.0
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ATRIP -1520.0
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ZNF233 -1320.0
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ZNF565 -886.0
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ZNF443 -858.0
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ZNF429 -798.0
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CITED4 -784.0
ZNF442 -776.0
ZNF669 -756.0
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RING1 -731.0
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DDIT4 -654.0
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GTF2H5 -649.0
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ZNF717 -493.0
ZNF764 -478.0
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ING2 -428.0
TAF7 -389.0
PSMB10 -372.0
RPAP2 -348.0
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TFAP2E -328.0
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ZNF619 -194.0
ZNF562 -175.0
ZNF747 -153.0
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PSMA4 -118.0
E2F1 -108.0
LEO1 -87.0
ARID1B -85.0
TMEM219 -63.0
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STK11 -41.0
KLF4 -9.0
ARID2 2.0
CDC26 6.0
CDK13 32.0
ZNF382 110.0
ZNF670 122.0
ANAPC10 141.0
ZNF778 195.0
ZNF546 201.0
PIN1 202.0
ZNF665 208.0
PSMD14 225.0
MLST8 236.0
UBE2E1 291.0
ZNF658B 296.0
SMARCB1 300.0
MED15 383.0
ZNF688 386.0
ZNF197 392.0
MED23 403.0
INTS9 406.0
THOC6 473.0
PIP4K2C 477.0
NELFB 490.0
MT-CO1 507.0
H2BC15 524.0
BNIP3L 581.0
UBE2I 587.0
RTF1 595.0
USP9X 622.0
NFYA 629.0
ZNF775 678.0
ZNF547 680.0
ZNF79 693.0
FANCC 704.0
NBN 709.0
THBS1 710.0
ZNF700 712.0
ZNF200 715.0
MT-CO2 729.0
ZNF99 738.0
ZNF703 740.0
GTF2H2 765.0
AURKB 781.0
TNRC6A 783.0
CDC7 815.0
PPARA 838.0
AFF4 868.0
ANAPC4 875.0
U2AF2 883.0
ZNF655 936.0
RNGTT 940.0
ZNF720 944.0
INTS2 969.0
U2AF1L4 985.0
DHX38 1001.0
PSMF1 1056.0
ZNF668 1077.0
ELL2 1128.0
INTS7 1160.0
MTOR 1162.0
SIRT3 1188.0
CAMK2G 1201.0
APOE 1230.0
OPRM1 1233.0
FAS 1236.0
PCGF2 1249.0
CNOT11 1260.0
MDM4 1276.0
CDC25C 1278.0
NELFCD 1287.0
COX7A2L 1305.0
ELOA 1352.0
TAF2 1359.0
CRADD 1378.0
PSMC4 1389.0
THOC7 1391.0
JUNB 1397.0
TBL1XR1 1405.0
EZH2 1417.0
RPRD1A 1459.0
SCO2 1489.0
GATAD2A 1499.0
PRELID3A 1500.0
SNW1 1506.0
MTA2 1515.0
TAF4 1523.0
PSMD7 1547.0
SUPT6H 1566.0
RNF111 1594.0
RPRD1B 1621.0
TCF12 1625.0
MED14 1629.0
CDC73 1632.0
ZNF394 1687.0
GTF2A2 1705.0
ZKSCAN3 1711.0
ZNF215 1759.0
PRMT5 1768.0
L3MBTL1 1780.0
FZR1 1793.0
NOC2L 1827.0
ITCH 1890.0
DPY30 1895.0
ITGA2B 1927.0
COX4I1 1963.0
SARNP 1972.0
MED16 2006.0
YWHAB 2038.0
DDX39B 2041.0
LAMTOR3 2053.0
GATAD2B 2086.0
PAPOLA 2096.0
USP7 2097.0
KAT5 2121.0
RRM2B 2176.0
PSMC3 2182.0
ZNF586 2251.0
ZNF205 2254.0
ZKSCAN4 2263.0
ZNF354A 2274.0
GTF2H4 2296.0
UBE2S 2306.0
MAPKAP1 2319.0
HUS1 2327.0
HDAC1 2347.0
HDAC6 2445.0
CBX8 2485.0
ZNF34 2486.0
MED26 2492.0
CDK12 2497.0
PCF11 2498.0
GSK3B 2520.0
PML 2526.0
PBRM1 2551.0
SFN 2567.0
PABPN1 2573.0
MLH1 2650.0
AGO3 2652.0
MED24 2654.0
GPS2 2679.0
CHEK2 2738.0
HDAC11 2741.0
ZNF195 2775.0
ZNF587 2779.0
EAF1 2783.0
RYBP 2806.0
SIN3B 2807.0
ANAPC7 2814.0
WWTR1 2858.0
PTPN11 2859.0
ITGAL 2879.0
ZNF697 2897.0
PPM1D 2954.0
H2AZ1 2960.0
ZNF25 2993.0
TSC1 3041.0
KRAS 3113.0
SMURF1 3123.0
CDKN1A 3132.0
ZNF160 3152.0
GTF2B 3189.0
PPARGC1B 3227.0
ZNF839 3264.0
AURKA 3271.0
H2BC11 3290.0
CBX6 3339.0
ZNF691 3347.0
CDC40 3360.0
SUPT4H1 3363.0
ZKSCAN5 3393.0
HDAC5 3445.0
POLR2L 3450.0
PSMA1 3451.0
TAF11 3477.0
PSMC6 3483.0
SMAD2 3495.0
DDIT3 3500.0
CBX3 3505.0
EHMT1 3558.0
TAF6 3570.0
PLK3 3589.0
HIVEP3 3609.0
SUMO1 3612.0
CLP1 3627.0
TBL1X 3644.0
CDK8 3675.0
RBX1 3691.0
CCNE2 3704.0
PSMB4 3707.0
ZNF613 3710.0
INTS12 3720.0
U2AF1 3739.0
PSMD13 3770.0
H2BC17 3795.0
ZNF611 3811.0
INTS8 3812.0
SNRPG 3835.0
BGLAP 3845.0
ZFP69B 3903.0
ZNF750 3921.0
COX5A 3965.0
AGO2 3966.0
CDK9 4027.0
ZNF124 4029.0
ABL1 4039.0
RXRB 4044.0
NPPA 4111.0
ZNF490 4115.0
ZNF660 4122.0
VEGFA 4174.0
PSMD3 4177.0
SURF1 4179.0
GAD2 4204.0
ZNF713 4209.0
CNOT6 4214.0
PPM1A 4215.0
BANP 4218.0
H2BC4 4239.0
PSMA6 4263.0
PAF1 4267.0
CSNK2A2 4323.0
CASP10 4326.0
TFDP1 4357.0
ZNF471 4388.0
TAF8 4424.0
H2BC5 4435.0
RHEB 4447.0
PSMC2 4457.0
ANAPC11 4464.0
ZNF589 4465.0
SYMPK 4502.0
CDKN2A 4560.0
CPSF2 4583.0
RABGGTA 4589.0
PPP2R1A 4593.0
SSU72 4600.0
RMI2 4605.0
AR 4651.0
TSC2 4664.0
GPI 4667.0
SNAPC4 4669.0
PSMB2 4680.0
MOBP 4702.0
NR1I3 4742.0
CBX4 4754.0
ZKSCAN7 4766.0
ZNF556 4798.0
KMT2C 4799.0
CPSF1 4828.0
RFC2 4835.0
CPSF7 4872.0
ZNF718 4873.0
UBC 4874.0
PPP2CA 4882.0
CDK7 4908.0
TJP1 4924.0
GPRIN1 4940.0
FOXO4 4965.0
ZNF701 4975.0
RRAGD 5007.0
MED12 5009.0
TNFRSF10C 5056.0
SNAPC3 5115.0
DDB2 5186.0
HIPK1 5208.0
BRCA1 5214.0
ELL 5225.0
CCNK 5228.0
POLR2E 5238.0
GTF2F2 5263.0
PPP2CB 5377.0
LBR 5389.0
AKT2 5390.0
ERCC3 5421.0
PSMB8 5433.0
E2F4 5439.0
HDAC7 5441.0
NR1H3 5458.0
PSMD8 5474.0
INTS1 5484.0
GTF2F1 5494.0
MDM2 5532.0
PSMD2 5544.0
CREBBP 5593.0
HDAC10 5634.0
ZNF555 5649.0
ZNF282 5652.0
KMT2B 5686.0
POLR2G 5695.0
PSMD12 5714.0
POLR2F 5738.0
ZNF460 5743.0
PDPK1 5768.0
PSMC1 5778.0
SLC38A9 5807.0
COX7B 5839.0
NCOR1 5849.0
KCTD1 5860.0
SMARCA4 5879.0
NRBP1 5881.0
RBBP8 5902.0
PRDX1 5934.0
TP53INP1 6003.0
APAF1 6024.0
PSMD5 6029.0
SMARCC2 6070.0
H2BC12 6101.0
AKT1 6133.0
TP53BP2 6140.0
H2BC21 6180.0
ZNF347 6193.0
NDUFA4 6226.0
KCTD6 6231.0
CASP1 6238.0
GPX2 6305.0
NABP2 6310.0
CSTF3 6324.0
PSMD1 6354.0
POLR2A 6387.0
UBE2D3 6400.0
TEAD2 6420.0
GCK 6443.0
ZNF716 6445.0
POU2F2 6515.0
CSNK2B 6563.0
PSME3 6605.0
H3C15 6611.5
CPSF3 6658.0
ZNF468 6661.0
GTF2E2 6705.0
ZNF20 6712.0
EAF2 6757.0
FOXO3 6773.0
COX6A1 6782.0
SKIL 6805.0
SETD1B 6834.0
TNFRSF10D 6836.0
ZNF267 6837.0
KDM5B 6861.0
ELF2 6980.0
NOTCH1 6982.0
ASH2L 6997.0
RMI1 7005.0
SMARCD2 7040.0
SESN2 7055.0
PSMD11 7057.0
SRSF4 7078.0
CASC3 7085.0
PRKCB 7102.0
CCNH 7145.0
NRBF2 7187.0
TIGAR 7200.0
CTDP1 7209.0
PRKAG1 7316.0
PTEN 7321.0
MAML1 7341.0
ZFHX3 7416.0
POU2F1 7429.0
TAF13 7430.0
ZNF385A 7452.0
LAMTOR4 7482.0
HDAC3 7484.0
CTSK 7494.0
ELOB 7511.0
LSM10 7576.0
ZNF552 7580.0
TCF7L1 7623.0
H3-3A 7624.0
IRAK1 7649.0
LAMTOR5 7659.0
ELOC 7671.0
TNFRSF10B 7686.0
COX5B 7706.0
SEM1 7739.0
MED20 7833.0
HTT 7856.0
JAG1 7859.0
GATA1 7928.0
PSMB7 7941.0
BCL2L11 7982.0
POLR2J 7983.0
CSNK2A1 7984.0
IWS1 7996.0
SP1 8056.0
HIPK2 8076.0
CCNG2 8083.0
RRAGA 8084.0
KMT2D 8117.0
CTNNB1 8119.0
YWHAH 8129.0
MED8 8164.0
ERCC2 8166.0
NELFE 8177.0
SNAPC2 8214.0
TXNRD1 8216.0
ZNF18 8241.0
NDRG1 8350.0
ZNF445 8376.0
CITED2 8389.0
ZNF774 8392.0
CNOT3 8403.0
ZNF333 8425.0
ARID1A 8458.0
ZNF230 8483.0
NR6A1 8487.0
NOTCH2 8499.0
HES1 8540.0
SOD2 8563.0
SMARCD3 8576.0
YWHAE 8584.0
PSMB5 8625.0
TXN 8653.0
TAF12 8666.0
PRDX5 8681.0
RAD9B 8706.0
BID 8709.0
PSMA7 8719.0
PSMD6 8745.0
H2AC20 8783.0
EP300 8816.0
MED25 8855.0
TWIST2 8906.0
TOP3A 8956.0
PSMD9 9005.0
G6PC 9009.0
ZNF320 9036.0
PRKAB1 9059.0
BAX 9079.0
RUNX1 9132.0
ELL3 9173.0
PINK1 9176.0
UBE2D1 9204.0
MLLT1 9219.0
AGO1 9230.0
SRSF9 9246.0
CDKN2B 9248.0
PSMB6 9262.0
LGALS3 9294.0
ABCA6 9306.0
LAMTOR2 9311.0
NEDD4L 9328.0
COX8A 9349.0
ARID3A 9384.0
NR1H2 9385.0
CAT 9425.0
ZNF28 9436.0
CCND3 9462.0
PRELID1 9513.0
PLAGL1 9550.0
ZNF746 9581.0
COX6B1 9596.0
MAPK3 9636.0
SLC2A3 9751.0
PTPN1 9752.0
RB1 9765.0
HDAC8 9800.0
LAMTOR1 9855.0
RBPJ 9875.0
YWHAG 9892.0
PSMB3 9902.0
ANAPC15 9931.0
TGFA 9932.0
POLDIP3 10060.0
KCTD15 10061.0
THOC5 10063.0
AGO4 10068.0
TAF10 10093.0
ZNF213 10151.0
ITGA5 10158.0
KMT5A 10179.0
MAP2K6 10292.0
CARM1 10294.0
PSMD4 10295.0
RXRA 10309.0
SMAD6 10368.0
GADD45A 10397.0
HDAC4 10451.0
MAPK14 10466.0
MAML3 10499.0
RETN 10519.0
NABP1 10524.0
SATB2 10563.0
SOCS3 10637.0
LMO2 10663.0
FKBP5 10739.0
CSF1R 10769.0
GSR 10772.0
ESRRA 10775.0
DLX6 10792.0
STEAP3 10803.0
MAPK1 10847.0
INTS3 10878.0
G6PD 10938.0
CEBPB 11028.0
NFE2 11043.0
ZNF702P 11119.0
PHC2 11185.0
NFYC 11209.0
CTSL 11213.0
RARA 11226.0
ZNF710 11316.0
NLRC4 11341.0
NCOR2 11380.0
CDK5 11415.0
CR1 11436.0
NOTCH4 11483.0
SPI1 11522.0
BCL6 11526.0
RNU1-1 11559.5
PRKACA 11578.0
H2AJ 11606.0
PPARG 11631.0
VDR 11663.0
TCF7L2 11692.0
SMAD1 11709.0
TP53I3 11719.0
NOTCH3 11733.0


Generic Transcription Pathway

Generic Transcription Pathway
445
set Generic Transcription Pathway
setSize 1077
pANOVA 5.34e-20
s.dist -0.165
p.adjustANOVA 2.6e-18



Top enriched genes

Top 20 genes
GeneID Gene Rank
RORC -9883
KIT -9844
TCF7 -9843
NPM1 -9836
CAMK4 -9799
GLS -9763
NR3C2 -9761
FOXO1 -9743
ZNF711 -9729
RBL2 -9700
DYRK2 -9696
ZNF33B -9689
NFATC2 -9680
PERP -9667
NFYB -9659
ZNF551 -9658
RPA1 -9657
RUNX2 -9648
PRKCQ -9643
ZNF420 -9642

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RORC -9883.0
KIT -9844.0
TCF7 -9843.0
NPM1 -9836.0
CAMK4 -9799.0
GLS -9763.0
NR3C2 -9761.0
FOXO1 -9743.0
ZNF711 -9729.0
RBL2 -9700.0
DYRK2 -9696.0
ZNF33B -9689.0
NFATC2 -9680.0
PERP -9667.0
NFYB -9659.0
ZNF551 -9658.0
RPA1 -9657.0
RUNX2 -9648.0
PRKCQ -9643.0
ZNF420 -9642.0
PMAIP1 -9639.0
WWP1 -9624.0
SUPT16H -9598.0
FBXO32 -9595.0
ZNF530 -9593.0
RORA -9585.0
GATA3 -9575.0
LEF1 -9568.0
ZIK1 -9567.0
ZNF549 -9560.0
HSPD1 -9514.0
LRPPRC -9513.0
ZNF136 -9491.0
PTPN4 -9478.0
RAD1 -9471.0
CAMK2D -9460.0
ZNF287 -9448.0
TFDP2 -9444.0
IGFBP3 -9434.0
MYC -9418.0
STAT1 -9404.0
ZNF286A -9397.0
ANAPC1 -9394.0
NR1D2 -9362.0
ZNF208 -9334.0
TNFRSF18 -9325.0
NR1D1 -9318.0
ZNF566 -9289.0
CCND2 -9246.0
GAMT -9243.0
ZNF548 -9218.0
ZNF671 -9191.0
ZNF431 -9149.0
TNRC6C -9142.0
PARP1 -9133.0
ZNF14 -9130.0
CNOT6L -9114.0
WRN -9097.0
ZNF681 -9089.0
ZNF544 -9084.0
PCGF5 -9061.0
SSRP1 -9045.0
ZNF112 -9037.0
ZNF583 -9026.0
ZNF568 -9016.0
RGCC -9009.0
PRR5 -9001.0
ZFP28 -8997.0
ZNF416 -8970.0
RUNX3 -8952.0
FASLG -8936.0
ING5 -8935.0
SIN3A -8913.0
CUL1 -8878.0
ZNF517 -8859.0
GLI3 -8843.0
TP53RK -8827.0
FANCD2 -8817.0
PLXNA4 -8810.0
AUTS2 -8807.0
ZNF184 -8799.0
PRMT6 -8789.0
ZNF485 -8781.0
ERBB2 -8774.0
AKT3 -8761.0
EPC1 -8757.0
ZNF567 -8743.0
ZNF337 -8725.0
RPS27A -8722.0
ZNF473 -8717.0
ZNF202 -8715.0
GLS2 -8711.0
BMI1 -8707.0
RFC3 -8694.0
ZNF354C -8658.0
ZNF749 -8639.0
ZNF74 -8635.0
TP53 -8613.0
CNOT7 -8609.0
ZNF664 -8578.0
YEATS4 -8569.0
CDK4 -8539.0
JMY -8535.0
ZNF599 -8495.0
ZNF302 -8478.0
ZNF211 -8472.0
ZNF559 -8449.0
ZNF708 -8431.0
CCNG1 -8400.0
BRD1 -8393.0
ZFP1 -8379.0
COX11 -8355.0
PPP1R13B -8332.0
ZNF30 -8321.0
ZNF678 -8303.0
ZNF331 -8301.0
ZNF430 -8300.0
ZNF696 -8297.0
ZNF43 -8258.0
SMURF2 -8254.0
ZNF721 -8249.0
ZNF616 -8248.0
SCMH1 -8236.0
ZNF354B -8182.0
POLR2D -8160.0
ZNF727 -8137.0
ZNF253 -8107.0
GPAM -8085.0
ZNF554 -8080.0
ZNF138 -8077.0
CDC23 -8076.0
ZNF786 -8075.0
RPA3 -8069.0
BTG2 -8011.0
TRIM28 -7995.0
BLK -7991.0
TAF4B -7985.0
ZNF737 -7984.0
GTF2H3 -7969.0
ITGA4 -7966.0
KAT2A -7883.0
PVALB -7854.0
CLDN5 -7851.0
GATA2 -7834.0
ZNF675 -7824.0
ZNF792 -7822.0
ZNF263 -7806.0
ZNF257 -7772.0
RAD17 -7742.0
RFC4 -7736.0
ZNF248 -7734.0
MEAF6 -7722.0
WWOX -7721.0
ZNF707 -7688.0
SIRT1 -7685.0
PPP2R5C -7679.0
KRBOX4 -7673.0
PRMT1 -7660.0
E2F6 -7656.0
PRDM1 -7655.0
ZNF571 -7638.0
PSMB9 -7625.0
HDAC9 -7621.0
ZNF3 -7533.0
NR2C2AP -7518.0
ATM -7513.0
ZSCAN25 -7509.0
CDKN1B -7508.0
MED10 -7505.0
ZNF519 -7492.0
ZNF614 -7476.0
TCEA1 -7475.0
TGIF2 -7440.0
PIP4K2B -7436.0
ZNF101 -7429.0
ZNF597 -7426.0
CASP6 -7413.0
ZNF649 -7409.0
MSH2 -7399.0
ZNF432 -7398.0
ZNF570 -7391.0
SMARCC1 -7357.0
PPARD -7353.0
ZNF446 -7335.0
MAML2 -7323.0
RBBP7 -7322.0
ZNF773 -7319.0
YY1 -7301.0
ZNF343 -7298.0
ZNF510 -7293.0
CBX5 -7291.0
ZNF266 -7285.0
HDAC2 -7259.0
ZNF777 -7250.0
ZNF529 -7243.0
ZNF682 -7242.0
TNKS1BP1 -7235.0
ZNF550 -7211.0
MECP2 -7198.0
ZNF317 -7195.0
ZNF2 -7189.0
ZNF540 -7187.0
ANAPC16 -7186.0
GTF2H1 -7185.0
ZNF17 -7178.0
PCBP4 -7141.0
ZNF582 -7125.0
TAF9B -7121.0
ZNF483 -7106.0
ZNF486 -7103.0
CCNC -7102.0
ESR2 -7042.0
FANCI -7036.0
ZNF600 -7033.0
DGCR8 -7022.0
CHD3 -7016.0
MED6 -6963.0
MDC1 -6961.0
ZNF793 -6927.0
ZNF772 -6917.0
DLL1 -6916.0
CENPJ -6905.0
KMT2A -6885.0
ZNF383 -6874.0
PCNA -6841.0
PHC1 -6810.0
IL2RA -6803.0
L3MBTL2 -6802.0
ZFP30 -6773.0
BTG1 -6755.0
ZNF740 -6726.0
E2F7 -6721.0
RBL1 -6718.0
ZNF584 -6710.0
SMAD3 -6699.0
ZNF12 -6648.0
ZNF141 -6647.0
ZNF514 -6637.0
ZNF761 -6633.0
ZNF419 -6622.0
ZNF563 -6608.0
ZNF771 -6602.0
SESN1 -6578.0
ZNF493 -6569.0
ZNF799 -6567.0
TAF9 -6564.0
ZNF45 -6562.0
ZNF10 -6560.0
ZNF324 -6487.0
ZNF543 -6479.0
ZNF492 -6453.0
CTLA4 -6445.0
ZNF274 -6415.0
THRA -6404.0
PSME1 -6399.0
PSMA5 -6362.0
ZNF417 -6355.0
ZNF180 -6353.0
MGA -6292.0
ZNF662 -6282.0
ZNF23 -6276.0
NOP2 -6275.0
H2BC9 -6264.0
BRIP1 -6240.0
COX20 -6229.0
ZNF470 -6183.0
ZNF175 -6179.0
ZNF300 -6165.0
SUZ12 -6160.0
KRBA1 -6145.0
ZNF212 -6117.0
YWHAQ -6039.0
CHEK1 -6036.0
ZFP37 -6030.0
ZSCAN32 -5996.0
ZNF506 -5994.0
ZKSCAN8 -5986.0
ZNF564 -5972.0
SMAD4 -5969.0
AXIN1 -5965.0
IFNG -5957.0
TAF3 -5912.0
PIP4K2A -5911.0
PSMC5 -5909.0
H2AZ2 -5901.0
COX16 -5896.0
ZFPM1 -5886.0
RICTOR -5883.0
PHF20 -5876.0
SMYD2 -5873.0
THRB -5858.0
MBD3 -5834.0
ZNF714 -5800.0
SKP1 -5791.0
MAF -5776.0
ZNF140 -5768.0
MED30 -5762.0
RRM2 -5738.0
ZNF75A -5735.0
ZNF680 -5733.0
ZFP2 -5716.0
ZNF736 -5696.0
ZNF227 -5693.0
MED17 -5686.0
CCNT1 -5679.0
YES1 -5662.0
MNAT1 -5650.0
ZNF135 -5640.0
NR2C1 -5634.0
PAX5 -5611.0
ZFP90 -5598.0
EED -5587.0
ZNF461 -5579.0
TRPC3 -5571.0
CDK1 -5568.0
ZNF626 -5567.0
SETD1A -5546.0
SRC -5527.0
ZNF607 -5518.0
ZNF484 -5467.0
ZNF480 -5463.0
TAF5 -5438.0
TCF3 -5430.0
ZNF528 -5423.0
ZNF441 -5420.0
TGIF1 -5418.0
ZNF557 -5417.0
ZNF334 -5412.0
ZNF595 -5408.0
ZNF285 -5404.0
ATAD2 -5373.0
TP73 -5371.0
SGK1 -5363.0
E2F5 -5304.0
ZNF677 -5291.0
PF4 -5240.0
ZNF77 -5236.0
ACTL6A -5233.0
CALM1 -5150.0
ZNF154 -5129.0
POLR2B -5111.0
RAD9A -5073.0
ZNF860 -5072.0
ZNF726 -5039.0
ZNF398 -5024.0
SETD9 -5013.0
ZNF621 -5009.0
ZNF606 -4990.0
ZNF439 -4984.0
RHNO1 -4965.0
MRE11 -4960.0
ATF2 -4941.0
TACO1 -4896.0
RBBP5 -4861.0
PPP1R13L -4855.0
ESR1 -4853.0
MYBL2 -4826.0
UXT -4808.0
SKI -4796.0
ZNF92 -4794.0
ZNF658 -4768.0
BCL2L14 -4758.0
NR4A2 -4739.0
ZNF33A -4735.0
ZNF235 -4716.0
ZNF425 -4682.0
ZNF782 -4681.0
ZNF610 -4659.0
RBBP4 -4658.0
ZNF706 -4651.0
ZNF26 -4650.0
CDK6 -4636.0
CYCS -4630.0
RPA2 -4620.0
ZNF226 -4609.0
VENTX -4606.0
PSMD10 -4578.0
MYL9 -4572.0
ZNF561 -4564.0
COX18 -4521.0
BRPF3 -4516.0
TXNIP -4515.0
SMAD7 -4508.0
SMARCD1 -4507.0
MAX -4483.0
TRIAP1 -4446.0
BLM -4432.0
CDK5R1 -4421.0
ZNF157 -4363.0
ZNF624 -4347.0
MAPKAPK5 -4344.0
PSMA3 -4338.0
ZNF273 -4297.0
ZNF415 -4294.0
EXO1 -4293.0
ZNF605 -4291.0
MT-CO3 -4247.0
PRKAB2 -4214.0
MED1 -4211.0
ZNF436 -4168.0
PRDX2 -4140.0
RABGGTB -4135.0
ZNF268 -4119.0
ZNF70 -4112.0
ZNF75D -4103.0
RAD51D -4074.0
RAD50 -4065.0
PMS2 -4051.0
NR3C1 -4034.0
ZNF324B -4025.0
NR2C2 -4024.0
DNA2 -4017.0
ZNF100 -4004.0
RFC5 -3986.0
ZNF573 -3982.0
RARG -3923.0
ANAPC5 -3910.0
POLR2K -3902.0
ZNF776 -3896.0
FOXP3 -3879.0
NR4A3 -3862.0
ZNF264 -3850.0
MEN1 -3826.0
FOS -3812.0
MEF2C -3791.0
CREB1 -3751.0
CAV1 -3722.0
CCND1 -3717.0
ZFP14 -3704.0
CDK2 -3694.0
ELF1 -3678.0
MED13 -3648.0
ZNF699 -3639.0
DAXX -3631.0
POLR2H -3611.0
CHD4 -3602.0
ZNF627 -3589.0
PSME2 -3570.0
ZNF500 -3548.0
TAF15 -3527.0
ZNF234 -3523.0
PHC3 -3455.0
ZNF689 -3443.0
ZNF770 -3413.0
TAF1 -3331.0
PIDD1 -3316.0
TNFRSF10A -3294.0
ZNF724 -3257.0
ZNF620 -3202.0
LDB1 -3194.0
SESN3 -3156.0
CBFB -3135.0
ZNF223 -3118.0
ZNF496 -3117.0
CASP2 -3098.0
TBP -3090.0
TAL1 -3086.0
NR4A1 -3071.0
ZNF440 -3050.0
CNOT4 -3031.0
ZNF738 -2974.0
COX6C -2943.0
SOCS4 -2911.0
PPP2R1B -2904.0
ZNF221 -2892.0
RNF34 -2887.0
ZNF418 -2878.0
NUAK1 -2825.0
ZNF569 -2823.0
ZNF426 -2817.0
SMARCA2 -2810.0
CCNE1 -2791.0
COX19 -2785.0
ATR -2784.0
ZNF19 -2752.0
PCGF6 -2701.0
ZNF222 -2699.0
MYB -2685.0
SUPT5H -2649.0
SMARCE1 -2634.0
ZNF785 -2631.0
BRD2 -2613.0
ZNF791 -2598.0
POLR2C -2566.0
RELA -2563.0
CDC27 -2558.0
ZNF615 -2556.0
ZNF577 -2545.0
ZNF433 -2539.0
CCNB1 -2524.0
TPX2 -2523.0
ZNF350 -2515.0
ZNF585B -2491.0
CHM -2462.0
ZNF250 -2447.0
UBB -2442.0
ZNF790 -2365.0
STUB1 -2360.0
ZFP69 -2359.0
ZNF692 -2346.0
ZNF596 -2344.0
BBC3 -2320.0
NR2F6 -2292.0
ZNF684 -2249.0
H19 -2242.0
ZNF224 -2234.0
ZNF521 -2233.0
CCNA1 -2231.0
H2BU1 -2206.0
ZNF625 -2189.0
RPTOR -2185.0
ANAPC2 -2172.0
RNF2 -2168.0
NFKB1 -2166.0
KAT6A -2151.0
ZNF676 -2148.0
DEK -2126.0
UBE2C -2114.0
RRAGB -2098.0
CNOT10 -2083.0
COX7C -2078.0
PSMA2 -2032.0
ZNF767P -2005.0
MOV10 -1996.0
MED31 -1991.0
FBXW7 -1985.0
PSMB1 -1960.0
ZNF558 -1914.0
E2F8 -1908.0
RFFL -1875.0
KAT2B -1851.0
CBX2 -1835.0
TOPBP1 -1834.0
H2AC6 -1829.0
ZNF709 -1764.0
ZNF41 -1759.0
CCNA2 -1727.0
ZNF585A -1657.0
RAD51 -1636.0
WDR5 -1634.0
CDC16 -1623.0
POLR2I -1599.0
COX14 -1533.0
ATRIP -1520.0
RRAGC -1512.0
BRPF1 -1446.0
JUN -1440.0
UBA52 -1437.0
ZNF155 -1397.0
ZNF37A -1387.0
TRIM33 -1385.0
MAMLD1 -1361.0
ZNF133 -1328.0
ZNF233 -1320.0
EHMT2 -1260.0
PRKAG2 -1248.0
ZNF189 -1236.0
SCO1 -1188.0
KMT2E -1148.0
ZNF667 -1141.0
PRKAA1 -1137.0
PPARGC1A -1095.0
PSME4 -1087.0
SERPINE1 -1083.0
YAF2 -1080.0
OCLN -1071.0
CNOT1 -1042.0
ZNF71 -1004.0
TNRC6B -914.0
ZNF565 -886.0
AIFM2 -878.0
ZNF443 -858.0
PLK2 -850.0
ZKSCAN1 -838.0
CCNT2 -837.0
TTC5 -814.0
ZNF429 -798.0
BRD7 -791.0
CITED4 -784.0
ZNF442 -776.0
ZNF669 -756.0
SREBF1 -751.0
RING1 -731.0
POMC -667.0
DDIT4 -654.0
GTF2H5 -649.0
YWHAZ -647.0
AGRP -618.0
TGFB1 -615.0
CTSV -594.0
ZNF641 -585.0
NELFA -564.0
MED7 -535.0
BARD1 -534.0
SKP2 -520.0
CNOT2 -518.0
ZNF717 -493.0
ZNF764 -478.0
RBM14 -432.0
ING2 -428.0
TAF7 -389.0
PSMB10 -372.0
BIRC5 -333.0
TFAP2E -328.0
MED4 -312.0
ATXN3 -290.0
GP1BA -285.0
MAPK11 -273.0
CNOT8 -257.0
ZNF169 -202.0
ZNF619 -194.0
ZNF562 -175.0
ZNF747 -153.0
PSMA4 -118.0
E2F1 -108.0
ARID1B -85.0
TMEM219 -63.0
MED27 -50.0
STK11 -41.0
KLF4 -9.0
ARID2 2.0
CDC26 6.0
CDK13 32.0
ZNF382 110.0
ZNF670 122.0
ANAPC10 141.0
ZNF778 195.0
ZNF546 201.0
PIN1 202.0
ZNF665 208.0
PSMD14 225.0
MLST8 236.0
UBE2E1 291.0
ZNF658B 296.0
SMARCB1 300.0
MED15 383.0
ZNF688 386.0
ZNF197 392.0
MED23 403.0
PIP4K2C 477.0
NELFB 490.0
MT-CO1 507.0
H2BC15 524.0
BNIP3L 581.0
UBE2I 587.0
USP9X 622.0
NFYA 629.0
ZNF775 678.0
ZNF547 680.0
ZNF79 693.0
FANCC 704.0
NBN 709.0
THBS1 710.0
ZNF700 712.0
ZNF200 715.0
MT-CO2 729.0
ZNF99 738.0
ZNF703 740.0
GTF2H2 765.0
AURKB 781.0
TNRC6A 783.0
CDC7 815.0
PPARA 838.0
ANAPC4 875.0
ZNF655 936.0
ZNF720 944.0
PSMF1 1056.0
ZNF668 1077.0
MTOR 1162.0
SIRT3 1188.0
CAMK2G 1201.0
APOE 1230.0
OPRM1 1233.0
FAS 1236.0
PCGF2 1249.0
CNOT11 1260.0
MDM4 1276.0
CDC25C 1278.0
NELFCD 1287.0
COX7A2L 1305.0
ELOA 1352.0
TAF2 1359.0
CRADD 1378.0
PSMC4 1389.0
JUNB 1397.0
TBL1XR1 1405.0
EZH2 1417.0
SCO2 1489.0
GATAD2A 1499.0
PRELID3A 1500.0
SNW1 1506.0
MTA2 1515.0
TAF4 1523.0
PSMD7 1547.0
RNF111 1594.0
TCF12 1625.0
MED14 1629.0
ZNF394 1687.0
ZKSCAN3 1711.0
ZNF215 1759.0
PRMT5 1768.0
L3MBTL1 1780.0
FZR1 1793.0
NOC2L 1827.0
ITCH 1890.0
DPY30 1895.0
ITGA2B 1927.0
COX4I1 1963.0
MED16 2006.0
YWHAB 2038.0
LAMTOR3 2053.0
GATAD2B 2086.0
USP7 2097.0
KAT5 2121.0
RRM2B 2176.0
PSMC3 2182.0
ZNF586 2251.0
ZNF205 2254.0
ZKSCAN4 2263.0
ZNF354A 2274.0
GTF2H4 2296.0
UBE2S 2306.0
MAPKAP1 2319.0
HUS1 2327.0
HDAC1 2347.0
HDAC6 2445.0
CBX8 2485.0
ZNF34 2486.0
MED26 2492.0
CDK12 2497.0
GSK3B 2520.0
PML 2526.0
PBRM1 2551.0
SFN 2567.0
MLH1 2650.0
AGO3 2652.0
MED24 2654.0
GPS2 2679.0
CHEK2 2738.0
HDAC11 2741.0
ZNF195 2775.0
ZNF587 2779.0
RYBP 2806.0
SIN3B 2807.0
ANAPC7 2814.0
WWTR1 2858.0
PTPN11 2859.0
ITGAL 2879.0
ZNF697 2897.0
PPM1D 2954.0
H2AZ1 2960.0
ZNF25 2993.0
TSC1 3041.0
KRAS 3113.0
SMURF1 3123.0
CDKN1A 3132.0
ZNF160 3152.0
PPARGC1B 3227.0
ZNF839 3264.0
AURKA 3271.0
H2BC11 3290.0
CBX6 3339.0
ZNF691 3347.0
SUPT4H1 3363.0
ZKSCAN5 3393.0
HDAC5 3445.0
POLR2L 3450.0
PSMA1 3451.0
TAF11 3477.0
PSMC6 3483.0
SMAD2 3495.0
DDIT3 3500.0
CBX3 3505.0
EHMT1 3558.0
TAF6 3570.0
PLK3 3589.0
HIVEP3 3609.0
SUMO1 3612.0
TBL1X 3644.0
CDK8 3675.0
RBX1 3691.0
CCNE2 3704.0
PSMB4 3707.0
ZNF613 3710.0
PSMD13 3770.0
H2BC17 3795.0
ZNF611 3811.0
BGLAP 3845.0
ZFP69B 3903.0
ZNF750 3921.0
COX5A 3965.0
AGO2 3966.0
CDK9 4027.0
ZNF124 4029.0
ABL1 4039.0
RXRB 4044.0
NPPA 4111.0
ZNF490 4115.0
ZNF660 4122.0
VEGFA 4174.0
PSMD3 4177.0
SURF1 4179.0
GAD2 4204.0
ZNF713 4209.0
CNOT6 4214.0
PPM1A 4215.0
BANP 4218.0
H2BC4 4239.0
PSMA6 4263.0
CSNK2A2 4323.0
CASP10 4326.0
TFDP1 4357.0
ZNF471 4388.0
H2BC5 4435.0
RHEB 4447.0
PSMC2 4457.0
ANAPC11 4464.0
ZNF589 4465.0
CDKN2A 4560.0
RABGGTA 4589.0
PPP2R1A 4593.0
RMI2 4605.0
AR 4651.0
TSC2 4664.0
GPI 4667.0
PSMB2 4680.0
MOBP 4702.0
NR1I3 4742.0
CBX4 4754.0
ZKSCAN7 4766.0
ZNF556 4798.0
KMT2C 4799.0
RFC2 4835.0
ZNF718 4873.0
UBC 4874.0
PPP2CA 4882.0
CDK7 4908.0
TJP1 4924.0
GPRIN1 4940.0
FOXO4 4965.0
ZNF701 4975.0
RRAGD 5007.0
MED12 5009.0
TNFRSF10C 5056.0
DDB2 5186.0
HIPK1 5208.0
BRCA1 5214.0
ELL 5225.0
CCNK 5228.0
POLR2E 5238.0
GTF2F2 5263.0
PPP2CB 5377.0
LBR 5389.0
AKT2 5390.0
ERCC3 5421.0
PSMB8 5433.0
E2F4 5439.0
HDAC7 5441.0
NR1H3 5458.0
PSMD8 5474.0
GTF2F1 5494.0
MDM2 5532.0
PSMD2 5544.0
CREBBP 5593.0
HDAC10 5634.0
ZNF555 5649.0
ZNF282 5652.0
KMT2B 5686.0
POLR2G 5695.0
PSMD12 5714.0
POLR2F 5738.0
ZNF460 5743.0
PDPK1 5768.0
PSMC1 5778.0
SLC38A9 5807.0
COX7B 5839.0
NCOR1 5849.0
KCTD1 5860.0
SMARCA4 5879.0
NRBP1 5881.0
RBBP8 5902.0
PRDX1 5934.0
TP53INP1 6003.0
APAF1 6024.0
PSMD5 6029.0
SMARCC2 6070.0
H2BC12 6101.0
AKT1 6133.0
TP53BP2 6140.0
H2BC21 6180.0
ZNF347 6193.0
NDUFA4 6226.0
KCTD6 6231.0
CASP1 6238.0
GPX2 6305.0
PSMD1 6354.0
POLR2A 6387.0
UBE2D3 6400.0
TEAD2 6420.0
GCK 6443.0
ZNF716 6445.0
CSNK2B 6563.0
PSME3 6605.0
H3C15 6611.5
ZNF468 6661.0
ZNF20 6712.0
FOXO3 6773.0
COX6A1 6782.0
SKIL 6805.0
SETD1B 6834.0
TNFRSF10D 6836.0
ZNF267 6837.0
KDM5B 6861.0
ELF2 6980.0
NOTCH1 6982.0
ASH2L 6997.0
RMI1 7005.0
SMARCD2 7040.0
SESN2 7055.0
PSMD11 7057.0
PRKCB 7102.0
CCNH 7145.0
NRBF2 7187.0
TIGAR 7200.0
CTDP1 7209.0
PRKAG1 7316.0
PTEN 7321.0
MAML1 7341.0
ZFHX3 7416.0
TAF13 7430.0
ZNF385A 7452.0
LAMTOR4 7482.0
HDAC3 7484.0
CTSK 7494.0
ELOB 7511.0
ZNF552 7580.0
TCF7L1 7623.0
H3-3A 7624.0
IRAK1 7649.0
LAMTOR5 7659.0
ELOC 7671.0
TNFRSF10B 7686.0
COX5B 7706.0
SEM1 7739.0
MED20 7833.0
HTT 7856.0
JAG1 7859.0
GATA1 7928.0
PSMB7 7941.0
BCL2L11 7982.0
POLR2J 7983.0
CSNK2A1 7984.0
SP1 8056.0
HIPK2 8076.0
CCNG2 8083.0
RRAGA 8084.0
KMT2D 8117.0
CTNNB1 8119.0
YWHAH 8129.0
MED8 8164.0
ERCC2 8166.0
NELFE 8177.0
TXNRD1 8216.0
ZNF18 8241.0
NDRG1 8350.0
ZNF445 8376.0
CITED2 8389.0
ZNF774 8392.0
CNOT3 8403.0
ZNF333 8425.0
ARID1A 8458.0
ZNF230 8483.0
NR6A1 8487.0
NOTCH2 8499.0
HES1 8540.0
SOD2 8563.0
SMARCD3 8576.0
YWHAE 8584.0
PSMB5 8625.0
TXN 8653.0
TAF12 8666.0
PRDX5 8681.0
RAD9B 8706.0
BID 8709.0
PSMA7 8719.0
PSMD6 8745.0
H2AC20 8783.0
EP300 8816.0
MED25 8855.0
TWIST2 8906.0
TOP3A 8956.0
PSMD9 9005.0
G6PC 9009.0
ZNF320 9036.0
PRKAB1 9059.0
BAX 9079.0
RUNX1 9132.0
PINK1 9176.0
UBE2D1 9204.0
AGO1 9230.0
CDKN2B 9248.0
PSMB6 9262.0
LGALS3 9294.0
ABCA6 9306.0
LAMTOR2 9311.0
NEDD4L 9328.0
COX8A 9349.0
ARID3A 9384.0
NR1H2 9385.0
CAT 9425.0
ZNF28 9436.0
CCND3 9462.0
PRELID1 9513.0
PLAGL1 9550.0
ZNF746 9581.0
COX6B1 9596.0
MAPK3 9636.0
SLC2A3 9751.0
PTPN1 9752.0
RB1 9765.0
HDAC8 9800.0
LAMTOR1 9855.0
RBPJ 9875.0
YWHAG 9892.0
PSMB3 9902.0
ANAPC15 9931.0
TGFA 9932.0
KCTD15 10061.0
AGO4 10068.0
TAF10 10093.0
ZNF213 10151.0
ITGA5 10158.0
KMT5A 10179.0
MAP2K6 10292.0
CARM1 10294.0
PSMD4 10295.0
RXRA 10309.0
SMAD6 10368.0
GADD45A 10397.0
HDAC4 10451.0
MAPK14 10466.0
MAML3 10499.0
RETN 10519.0
SATB2 10563.0
SOCS3 10637.0
LMO2 10663.0
FKBP5 10739.0
CSF1R 10769.0
GSR 10772.0
ESRRA 10775.0
DLX6 10792.0
STEAP3 10803.0
MAPK1 10847.0
G6PD 10938.0
CEBPB 11028.0
NFE2 11043.0
ZNF702P 11119.0
PHC2 11185.0
NFYC 11209.0
CTSL 11213.0
RARA 11226.0
ZNF710 11316.0
NLRC4 11341.0
NCOR2 11380.0
CDK5 11415.0
CR1 11436.0
NOTCH4 11483.0
SPI1 11522.0
BCL6 11526.0
PRKACA 11578.0
H2AJ 11606.0
PPARG 11631.0
VDR 11663.0
TCF7L2 11692.0
SMAD1 11709.0
TP53I3 11719.0
NOTCH3 11733.0


Formation of the ternary complex, and subsequently, the 43S complex

Formation of the ternary complex, and subsequently, the 43S complex
398
set Formation of the ternary complex, and subsequently, the 43S complex
setSize 51
pANOVA 2.8e-14
s.dist -0.615
p.adjustANOVA 1.31e-12



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS2 -9635
RPS3A -9257
RPS6 -9170
EIF3B -8874
RPS3 -8856
RPS25 -8832
RPS27A -8722
RPS5 -8698
EIF3E -8600
RPS20 -8476
RPS12 -8401
EIF1AX -8394
RPS14 -8337
RPS23 -8334
RPS27 -8260
RPS7 -8047
RPS15A -7912
EIF3L -7766
RPS4X -7636
RPS10 -7629

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS2 -9635
RPS3A -9257
RPS6 -9170
EIF3B -8874
RPS3 -8856
RPS25 -8832
RPS27A -8722
RPS5 -8698
EIF3E -8600
RPS20 -8476
RPS12 -8401
EIF1AX -8394
RPS14 -8337
RPS23 -8334
RPS27 -8260
RPS7 -8047
RPS15A -7912
EIF3L -7766
RPS4X -7636
RPS10 -7629
RPS16 -7617
RPS13 -7375
RPS18 -7288
RPS8 -7161
RPS17 -7134
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPS28 -6429
EIF3J -6001
EIF3H -5894
EIF3M -5620
RPS19 -5616
RPS26 -5524
RPS15 -5342
RPS24 -5310
RPSA -4559
EIF3D -4337
EIF3C -3750
EIF3F -3748
EIF2S1 -3350
EIF3I -2671
EIF3G -1676
EIF3A -1537
FAU -1029
EIF3K -298
EIF2S2 297
EIF2S3 1308
RPS4Y1 1461
RPS9 2392
RPS27L 2784


Regulation of expression of SLITs and ROBOs

Regulation of expression of SLITs and ROBOs
980
set Regulation of expression of SLITs and ROBOs
setSize 159
pANOVA 3.68e-14
s.dist -0.348
p.adjustANOVA 1.67e-12



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
ROBO3 -9256
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
ROBO3 -9256
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
RPS14 -8337
GSPT2 -8336
RPS23 -8334
RPL10 -8318
RPS27 -8260
RPLP2 -8255
NCBP2 -8212
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
UPF3A -7835
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
PSMB9 -7625
RPS16 -7617
RPL18A -7609
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
RPL7A -7296
RPS18 -7288
RPS8 -7161
RPS17 -7134
RNPS1 -7032
RPL19 -7006
RPL23 -6933
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPL37 -6660
RPL38 -6589
GSPT1 -6576
RPS28 -6429
PSME1 -6399
PSMA5 -6362
RPL36 -6343
RPL8 -6274
RPL27 -6068
RPL41 -6065
PSMC5 -5909
RPL39 -5790
RPS19 -5616
RPL13 -5550
RPS26 -5524
RPS15 -5342
RPS24 -5310
RPL37A -4774
PSMD10 -4578
RPSA -4559
PSMA3 -4338
RPL36AL -4148
MAGOHB -4045
RPLP1 -3887
PSME2 -3570
PABPC1 -3482
LDB1 -3194
UPF3B -3065
RBM8A -2980
UBB -2442
PSMA2 -2032
PSMB1 -1960
RPL28 -1952
MAGOH -1931
USP33 -1781
UBA52 -1437
NCBP1 -1125
PSME4 -1087
FAU -1029
EIF4A3 -915
PSMB10 -372
UPF2 -229
LHX4 -150
PSMA4 -118
RPL39L -69
PSMD14 225
CUL2 443
ROBO1 510
PSMF1 1056
PSMC4 1389
RPS4Y1 1461
PSMD7 1547
PSMC3 2182
RPS9 2392
DAG1 2432
RPS27L 2784
PSMA1 3451
PSMC6 3483
RBX1 3691
PSMB4 3707
PSMD13 3770
PSMD3 4177
PSMA6 4263
ETF1 4300
PSMC2 4457
PSMB2 4680
UBC 4874
PSMB8 5433
PSMD8 5474
PSMD2 5544
RPL3L 5700
PSMD12 5714
PSMC1 5778
PSMD5 6029
RPL26L1 6187
PSMD1 6354
PSME3 6605
PSMD11 7057
CASC3 7085
ELOB 7511
ELOC 7671
SEM1 7739
PSMB7 7941
PSMB5 8625
PSMA7 8719
PSMD6 8745
PSMD9 9005
PSMB6 9262
SLIT1 9684
PSMB3 9902
EIF4G1 9922
PSMD4 10295
ZSWIM8 10415


rRNA modification in the nucleus and cytosol

rRNA modification in the nucleus and cytosol
1352
set rRNA modification in the nucleus and cytosol
setSize 59
pANOVA 1.02e-13
s.dist -0.56
p.adjustANOVA 4.48e-12



Top enriched genes

Top 20 genes
GeneID Gene Rank
DKC1 -9835
NOP14 -9719
FBL -9671
RPS2 -9635
NOP58 -9366
NOL11 -9354
UTP4 -9338
NAT10 -9326
THUMPD1 -9311
DIMT1 -9230
WDR75 -9213
RPS6 -9170
BMS1 -9164
WDR43 -8851
NOP56 -8346
RPS14 -8337
UTP15 -8280
IMP4 -8233
RRP9 -8121
RPS7 -8047

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DKC1 -9835
NOP14 -9719
FBL -9671
RPS2 -9635
NOP58 -9366
NOL11 -9354
UTP4 -9338
NAT10 -9326
THUMPD1 -9311
DIMT1 -9230
WDR75 -9213
RPS6 -9170
BMS1 -9164
WDR43 -8851
NOP56 -8346
RPS14 -8337
UTP15 -8280
IMP4 -8233
RRP9 -8121
RPS7 -8047
SNU13 -7987
PDCD11 -7980
WDR3 -7973
DDX47 -7962
RCL1 -7761
PNO1 -7506
HEATR1 -7360
PWP2 -7199
IMP3 -6997
WDR46 -6977
NOL6 -6945
UTP20 -6898
EMG1 -6735
GAR1 -6696
MPHOSPH10 -6590
KRR1 -6432
NOP2 -6275
WDR36 -5853
DHX37 -5761
NHP2 -5747
UTP6 -5444
RRP7A -4574
DCAF13 -4245
UTP14A -3160
FCF1 -3010
UTP14C -1630
UTP3 -1460
TRMT112 -370
TSR3 -358
TBL3 55
RRP36 511
UTP11 1268
DDX52 1503
RPS9 2392
UTP18 3740
DDX49 4194
NOC4L 7461
NOP10 10793
SNORD3A 11429


Translation initiation complex formation

Translation initiation complex formation
1269
set Translation initiation complex formation
setSize 58
pANOVA 6.84e-13
s.dist -0.545
p.adjustANOVA 2.91e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS2 -9635
EIF4A2 -9355
RPS3A -9257
RPS6 -9170
EIF3B -8874
RPS3 -8856
RPS25 -8832
RPS27A -8722
RPS5 -8698
EIF3E -8600
RPS20 -8476
RPS12 -8401
EIF1AX -8394
RPS14 -8337
RPS23 -8334
EIF4B -8328
RPS27 -8260
RPS7 -8047
RPS15A -7912
EIF3L -7766

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS2 -9635
EIF4A2 -9355
RPS3A -9257
RPS6 -9170
EIF3B -8874
RPS3 -8856
RPS25 -8832
RPS27A -8722
RPS5 -8698
EIF3E -8600
RPS20 -8476
RPS12 -8401
EIF1AX -8394
RPS14 -8337
RPS23 -8334
EIF4B -8328
RPS27 -8260
RPS7 -8047
RPS15A -7912
EIF3L -7766
RPS4X -7636
RPS10 -7629
RPS16 -7617
RPS13 -7375
RPS18 -7288
RPS8 -7161
RPS17 -7134
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPS28 -6429
EIF3J -6001
EIF3H -5894
EIF3M -5620
RPS19 -5616
RPS26 -5524
RPS15 -5342
RPS24 -5310
RPSA -4559
EIF3D -4337
EIF3C -3750
EIF3F -3748
PABPC1 -3482
EIF2S1 -3350
EIF3I -2671
EIF3G -1676
EIF3A -1537
FAU -1029
EIF3K -298
EIF2S2 297
EIF2S3 1308
RPS4Y1 1461
EIF4E 2104
RPS9 2392
RPS27L 2784
EIF4A1 5928
EIF4H 7435
EIF4G1 9922


Membrane Trafficking

Membrane Trafficking
630
set Membrane Trafficking
setSize 558
pANOVA 8.92e-13
s.dist 0.177
p.adjustANOVA 3.68e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
AP2A1 11707
RIN1 11696
SERPINA1 11685
F5 11617
GNS 11592
PLIN3 11513
COG7 11491
AMPH 11449
ULK1 11434
SBF2 11367
BLOC1S1 11348
COPG1 11346
CUX1 11328
ARPC1A 11206
DENND3 11092
RIN2 11027
ARRB2 11021
GORASP1 10996
EPN1 10994
AP1B1 10946

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AP2A1 11707
RIN1 11696
SERPINA1 11685
F5 11617
GNS 11592
PLIN3 11513
COG7 11491
AMPH 11449
ULK1 11434
SBF2 11367
BLOC1S1 11348
COPG1 11346
CUX1 11328
ARPC1A 11206
DENND3 11092
RIN2 11027
ARRB2 11021
GORASP1 10996
EPN1 10994
AP1B1 10946
ITSN1 10929
GRB2 10925
RAC1 10907
RAB10 10903
SNX18 10894
DAB2 10889
RAB39A 10887
GJD3 10882
TBC1D2 10859
STX10 10849
AP1S1 10842
VPS37C 10801
GRK3 10799
CTSZ 10773
CD55 10741
SCARB2 10644
CHMP2A 10625
CHMP4B 10624
TBC1D14 10488
VPS25 10487
DCTN2 10458
AP2A2 10434
CYTH4 10395
ARF1 10356
RAB13 10352
FTL 10348
SEC24D 10340
GGA1 10328
GALNT2 10321
PREB 10297
SYNJ1 10251
RAB5C 10197
COL7A1 10174
KIF1C 10156
AP1M1 10145
IGF2R 10077
MAN1A1 10070
ACTR1A 10067
AP4M1 10058
ARPC5 10048
RAB31 10045
RAB32 10038
DENND5A 10034
SORT1 10018
TBC1D10B 9956
PLA2G4A 9943
CPD 9940
HGS 9939
TGFA 9932
RAB1A 9919
MON1B 9913
YWHAG 9892
EXOC1 9891
NSF 9858
HIP1 9850
COPA 9848
TBC1D1 9842
RALGAPA2 9821
PICALM 9814
DNM2 9736
TGOLN2 9729
GOLIM4 9711
OCRL 9709
MVB12A 9695
CHMP5 9670
MYO5A 9640
KIF1B 9632
GGA3 9615
TMED9 9614
ARF5 9584
KDELR1 9578
LDLR 9568
VAMP7 9561
TRAPPC12 9530
CTSC 9524
SNX2 9523
MAN2A2 9508
AP2S1 9504
ARPC3 9484
DCTN4 9451
RAB1B 9447
GRK2 9446
DENND4B 9426
CLTC 9346
UBAP1 9339
AGPAT3 9335
GAK 9326
DCTN6 9325
SEC16B 9315
SH3GL1 9314
AGFG1 9305
RAB7A 9295
NAA38 9238
ARPC4 9223
DCTN1 9214
ARPC2 9212
ARF4 9156
EXOC6 9137
EXOC7 9098
PRKAB1 9059
COG4 9044
CLTCL1 9020
LMAN2 8931
TRAPPC1 8880
PACSIN2 8869
CCZ1 8831
REPS2 8795
COPE 8787
NAPG 8778
CBL 8765
HPS1 8755
COPS7A 8689
COPG2 8671
BICD2 8632
SNAPIN 8619
ARF3 8602
CAPZB 8593
SNAP29 8589
YWHAE 8584
RIC1 8493
SNF8 8478
NAPA 8477
ALS2 8433
NEDD8 8396
GOLGA2 8366
VPS53 8331
GOLGA1 8280
CLTB 8275
DENND1A 8266
STX4 8182
YWHAH 8129
DYNC1LI2 8092
STX5 8070
CAPZA1 8032
VAMP3 8012
CAPZA2 7999
KLC1 7957
GABARAP 7950
RAB27A 7933
SCFD1 7929
PPP6R1 7922
DCTN3 7885
DYNC1LI1 7881
TFG 7873
SEC16A 7812
RAB36 7803
VTI1A 7757
CLTA 7680
RAB7B 7637
TOR1B 7635
RAB6A 7579
TOR1A 7549
CSNK1D 7458
ACTR2 7352
AP2M1 7323
PRKAG1 7316
MVB12B 7291
EXOC3 7224
LRP2 7216
EPS15L1 7199
PIP5K1C 7137
SYT11 7091
SEC24C 7065
TRAPPC3 7024
SEC24A 6928
FCHO2 6921
STXBP3 6903
TRAPPC11 6868
SEC13 6793
DNASE2 6747
ARFGAP2 6724
COPB2 6710
CHMP3 6707
CHMP6 6694
CHMP4A 6691
STX18 6681
ACTR3 6644
VPS37B 6524
GDI1 6479
YKT6 6467
FTH1 6366
KIF5B 6360
CNIH2 6334
MYH9 6290
GBF1 6282
COPB1 6181
AKT1 6133
SNX5 6119
SYT2 6082
ARFGAP1 6078
ITSN2 6016
KIF13B 6004
KIF6 5970
VPS52 5896
GJC1 5867
ARRB1 5865
AVPR2 5844
DNM1 5834
GAPVD1 5827
VPS37A 5731
DYNC1I2 5729
TBC1D24 5666
TSG101 5627
RACGAP1 5554
RABEPK 5549
SPTBN5 5455
TBC1D7 5417
AP3B1 5406
AKT2 5390
STX6 5374
GDI2 5257
YIPF6 5187
SURF4 5135
KIF23 5122
RHOQ 5105
TBC1D16 5070
KDELR2 4945
RAB5B 4935
TJP1 4924
RAB35 4902
TRAPPC8 4901
UBC 4874
RAB8B 4792
F8 4773
CCZ1B 4768
STAM2 4752
GOLGA5 4747
TSC2 4664
REPS1 4640
TRAPPC5 4592
SAR1B 4545
RABGEF1 4500
VPS45 4436
SEC24B 4410
PUM1 4404
KIF3B 4392
DENND2C 4372
RAB18 4366
SNAP23 4343
MIA2 4301
KIF3C 4286
VAMP8 4250
ACTR10 4228
SYT1 4178
RABGAP1 4163
CYTH2 4110
FNBP1L 4083
RAB8A 3907
NECAP1 3901
TMEM115 3887
TBC1D13 3874
USP6NL 3870
GABARAPL2 3855
EPS15 3853
AP1G1 3828
TF 3776
TMED3 3759
PAFAH1B1 3738
RAB5A 3708
MAP1LC3B 3686
NAPB 3641
DENND1C 3637
TPD52L1 3634
RAB11B 3598
KIF9 3582
EXOC4 3461
SPTB 3448
ARFGAP3 3442
GGA2 3422
MADD 3395
APP 3315
RAB3GAP2 3311
RGP1 3262
KLC3 3246
DYNLL1 3185
TBC1D8B 3146
AP3S1 3106
COPS5 3077
TFRC 3047
TSC1 3041
FZD4 3002
RAB14 2942
COPZ1 2925
KIF18B 2844
SNX9 2815
AP4E1 2808
GOSR2 2697
RAB43 2624
GALNT1 2613
RAB3GAP1 2608
SFN 2567
TRAPPC13 2482
DENND6B 2457
GJC2 2387
PAFAH1B2 2356
SEC22B 2167
CFTR 2137
TBC1D3 2123
ANKRD27 2095
TRAPPC2L 2058
YWHAB 2038
SEC31A 2016
RAB21 2011
CENPE 1952
STX16 1904
SEC23A 1838
KIFC2 1820
AP1S3 1783
VTA1 1763
TBC1D20 1725
ARCN1 1716
SH3KBP1 1675
LMAN2L 1671
VPS54 1639
SPTA1 1589
TRAPPC9 1554
RAB41 1492
RAB11A 1334
AP4B1 1250
RAB3A 1226
DYNC1I1 1191
CLINT1 1115
KIF2C 1104
KIAA0319 1066
TMED2 965
AREG 932
MON1A 905
COPS6 898
VPS28 893
DNAJC6 888
KIF19 826
DENND6A 816
KDELR3 810
RAB38 764
ANK1 741
COG5 706
MCFD2 660
SPTBN2 565
EXOC8 537
AP1G2 471
TRAPPC10 441
EREG 410
KIF27 249
COPS7B 246
EGF 238
KIF18A 102
STON1 7
VAMP4 -18
USO1 -110
FCHO1 -228
PPP6R3 -249
DNM3 -250
NECAP2 -326
ASPSCR1 -351
CHMP2B -392
HBEGF -398
TBC1D25 -415
TRAPPC6B -434
POLG -445
TMF1 -467
KIF21B -476
COPS2 -505
ACBD3 -610
UBQLN1 -627
VPS4B -630
RAB3IL1 -640
YWHAZ -647
RALGAPB -650
RAB12 -684
PIK3C2A -690
COPS3 -762
TBC1D10A -766
ARF6 -848
DCTN5 -898
NBAS -985
DYNC1H1 -1040
UBQLN2 -1116
EPN2 -1150
PPP6C -1168
KLC4 -1189
RAB33B -1199
PRKAG2 -1248
RAB3IP -1300
TRAPPC4 -1304
TMED7 -1318
COG8 -1340
WASL -1370
TBC1D17 -1399
KIF20A -1419
UBA52 -1437
VPS4A -1442
BLOC1S6 -1527
GPS1 -1667
FNBP1 -1683
C2CD5 -1853
SEC23IP -1883
AP4S1 -1900
KIF4A -1930
ARFIP2 -2077
BLOC1S3 -2366
GCC1 -2396
UBB -2442
CHM -2462
KIF26A -2475
BICD1 -2480
STAM -2492
SYTL1 -2519
EPGN -2690
M6PR -2706
COPS4 -2709
ZW10 -2813
EXOC5 -2814
MYO1C -2881
TRIP11 -2915
COG2 -2945
KIFC1 -2979
DENND4A -2989
RAB9A -3056
DTNBP1 -3111
MAN2A1 -3130
RAB27B -3133
STON2 -3139
SYS1 -3149
CNIH1 -3155
DENND2A -3181
USE1 -3189
KIF16B -3205
CD59 -3215
KIF15 -3250
KLC2 -3299
ARL1 -3337
BET1L -3403
RAB4A -3411
AP2B1 -3690
RAB33A -3731
LNPEP -3755
RAB6B -3798
SH3D19 -3800
COG3 -3840
GOLGA4 -3948
VPS36 -3954
MIA3 -3981
KIF11 -4054
GJB6 -4155
GOLGB1 -4180
TXNDC5 -4205
PRKAB2 -4214
CHML -4221
HPS4 -4226
RABEP1 -4244
CTTN -4321
PAFAH1B3 -4377
ARFRP1 -4510
SLC2A8 -4567
RAB9B -4668
BNIP1 -4852
CD4 -4882
DVL2 -4905
SEC22C -4952
TRIP10 -4971
DENND4C -5121
CALM1 -5150
DENND1B -5178
PLA2G6 -5218
KIFAP3 -5269
BET1 -5288
TBC1D15 -5322
COG1 -5406
GCC2 -5428
RINL -5487
COG6 -5508
SRC -5527
EXOC2 -5595
ANKRD28 -5772
CYTH3 -5975
ANK3 -5980
SBF1 -6038
YWHAQ -6039
GOSR1 -6194
MAN1A2 -6257
COPZ2 -6311
CNIH3 -6337
KIF26B -6414
KIF28P -6568
DENND5B -6724
AAK1 -6772
TMED10 -6868
ADRB2 -6879
NAA35 -7044
BLOC1S4 -7101
SEC22A -7145
TRAPPC2 -7210
VAMP2 -7244
KIF5A -7265
TBC1D10C -7271
KIF20B -7321
AP1M2 -7416
STX17 -7461
MYO6 -7690
AP1S2 -7941
RALA -7942
TRAPPC6A -8005
DYNLL2 -8015
CYTH1 -8122
COPS8 -8134
KIF21A -8147
BIN1 -8338
SCOC -8353
KIF2A -8455
VPS51 -8516
HIP1R -8643
SPTBN1 -8685
RINT1 -8687
RPS27A -8722
CD3D -8747
AKT3 -8761
KIF22 -8858
RHOBTB3 -8939
KIF3A -8957
RAB30 -8962
PACSIN1 -8985
LMAN1 -8999
CD3G -9125
OPTN -9165
HSPA8 -9166
NAA30 -9177
CHMP7 -9399
RAB39B -9422
DENND2D -9502
SPTAN1 -9516
TBC1D4 -9523
ALS2CL -9549
TPD52 -9559
SYNJ2 -9603
MAN1C1 -9615
LDLRAP1 -9809
KIF5C -9849
IL7R -9876


Ribosomal scanning and start codon recognition

Ribosomal scanning and start codon recognition
1015
set Ribosomal scanning and start codon recognition
setSize 58
pANOVA 1.1e-12
s.dist -0.54
p.adjustANOVA 4.39e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS2 -9635
EIF4A2 -9355
RPS3A -9257
RPS6 -9170
EIF3B -8874
RPS3 -8856
RPS25 -8832
RPS27A -8722
RPS5 -8698
EIF3E -8600
RPS20 -8476
RPS12 -8401
EIF1AX -8394
RPS14 -8337
RPS23 -8334
EIF4B -8328
RPS27 -8260
RPS7 -8047
RPS15A -7912
EIF3L -7766

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS2 -9635
EIF4A2 -9355
RPS3A -9257
RPS6 -9170
EIF3B -8874
RPS3 -8856
RPS25 -8832
RPS27A -8722
RPS5 -8698
EIF3E -8600
RPS20 -8476
RPS12 -8401
EIF1AX -8394
RPS14 -8337
RPS23 -8334
EIF4B -8328
RPS27 -8260
RPS7 -8047
RPS15A -7912
EIF3L -7766
RPS4X -7636
RPS10 -7629
RPS16 -7617
RPS13 -7375
RPS18 -7288
RPS8 -7161
RPS17 -7134
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPS28 -6429
EIF3J -6001
EIF3H -5894
EIF3M -5620
RPS19 -5616
RPS26 -5524
RPS15 -5342
RPS24 -5310
RPSA -4559
EIF3D -4337
EIF3C -3750
EIF3F -3748
EIF2S1 -3350
EIF3I -2671
EIF3G -1676
EIF3A -1537
FAU -1029
EIF5 -416
EIF3K -298
EIF2S2 297
EIF2S3 1308
RPS4Y1 1461
EIF4E 2104
RPS9 2392
RPS27L 2784
EIF4A1 5928
EIF4H 7435
EIF4G1 9922


Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S

Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
49
set Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
setSize 59
pANOVA 2.07e-12
s.dist -0.529
p.adjustANOVA 8.07e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS2 -9635
EIF4A2 -9355
RPS3A -9257
RPS6 -9170
EIF3B -8874
RPS3 -8856
RPS25 -8832
RPS27A -8722
RPS5 -8698
EIF3E -8600
RPS20 -8476
RPS12 -8401
EIF1AX -8394
RPS14 -8337
RPS23 -8334
EIF4B -8328
RPS27 -8260
RPS7 -8047
RPS15A -7912
EIF3L -7766

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS2 -9635
EIF4A2 -9355
RPS3A -9257
RPS6 -9170
EIF3B -8874
RPS3 -8856
RPS25 -8832
RPS27A -8722
RPS5 -8698
EIF3E -8600
RPS20 -8476
RPS12 -8401
EIF1AX -8394
RPS14 -8337
RPS23 -8334
EIF4B -8328
RPS27 -8260
RPS7 -8047
RPS15A -7912
EIF3L -7766
RPS4X -7636
RPS10 -7629
RPS16 -7617
RPS13 -7375
RPS18 -7288
RPS8 -7161
RPS17 -7134
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPS28 -6429
EIF3J -6001
EIF3H -5894
EIF3M -5620
RPS19 -5616
RPS26 -5524
RPS15 -5342
RPS24 -5310
RPSA -4559
EIF3D -4337
EIF3C -3750
EIF3F -3748
PABPC1 -3482
EIF2S1 -3350
EIF3I -2671
EIF3G -1676
EIF3A -1537
FAU -1029
EIF3K -298
EIF2S2 297
EIF2S3 1308
RPS4Y1 1461
EIF4E 2104
RPS9 2392
RPS27L 2784
EIF4EBP1 5335
EIF4A1 5928
EIF4H 7435
EIF4G1 9922


Signaling by ROBO receptors

Signaling by ROBO receptors
1130
set Signaling by ROBO receptors
setSize 199
pANOVA 8.42e-11
s.dist -0.267
p.adjustANOVA 3.19e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
NELL2 -9798
PRKACB -9741
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
ROBO3 -9256
PFN2 -9186
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
NCK1 -8821
RPL21 -8773
RPS27A -8722
RPS5 -8698

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NELL2 -9798
PRKACB -9741
RPL3 -9701
RPS2 -9635
RPL14 -9390
RPL23A -9382
RPL5 -9359
RPS3A -9257
ROBO3 -9256
PFN2 -9186
RPS6 -9170
RPL7 -9134
RPL4 -9065
RPL22 -8915
RPS3 -8856
RPS25 -8832
NCK1 -8821
RPL21 -8773
RPS27A -8722
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
EVL -8581
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
AKAP5 -8403
RPS12 -8401
RPS14 -8337
GSPT2 -8336
RPS23 -8334
RPL10 -8318
RPS27 -8260
RPLP2 -8255
NCBP2 -8212
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
UPF3A -7835
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
RPL35 -7710
RPL26 -7648
RPS4X -7636
RPS10 -7629
RPL24 -7626
PSMB9 -7625
RPS16 -7617
RPL18A -7609
PAK6 -7582
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
RPL7A -7296
RPS18 -7288
NCK2 -7245
RPS8 -7161
RPS17 -7134
RNPS1 -7032
RPL19 -7006
RPL23 -6933
RPS29 -6791
RPS11 -6742
RPS21 -6706
RPL37 -6660
RPL38 -6589
GSPT1 -6576
RPS28 -6429
PSME1 -6399
PSMA5 -6362
RPL36 -6343
RPL8 -6274
RPL27 -6068
RPL41 -6065
PSMC5 -5909
RPL39 -5790
PRKCA -5667
RPS19 -5616
RPL13 -5550
SRC -5527
RPS26 -5524
RPS15 -5342
RPS24 -5310
RPL37A -4774
CLASP2 -4711
PSMD10 -4578
RPSA -4559
PSMA3 -4338
RPL36AL -4148
MAGOHB -4045
RPLP1 -3887
PSME2 -3570
PABPC1 -3482
SOS1 -3263
LDB1 -3194
UPF3B -3065
RBM8A -2980
UBB -2442
CXCR4 -2277
PSMA2 -2032
PSMB1 -1960
RPL28 -1952
MAGOH -1931
USP33 -1781
ABL2 -1656
UBA52 -1437
NCBP1 -1125
PSME4 -1087
FAU -1029
EIF4A3 -915
NTN1 -826
PAK3 -533
ARHGAP39 -406
PSMB10 -372
UPF2 -229
LHX4 -150
PSMA4 -118
RPL39L -69
PSMD14 225
CUL2 443
ROBO1 510
GPC1 894
PSMF1 1056
CLASP1 1310
PSMC4 1389
RPS4Y1 1461
PSMD7 1547
PAK4 1988
PSMC3 2182
PPP3CB 2367
RPS9 2392
DAG1 2432
SLIT3 2533
RPS27L 2784
PRKAR2A 2979
PSMA1 3451
PSMC6 3483
RBX1 3691
PSMB4 3707
PSMD13 3770
ABL1 4039
PSMD3 4177
PSMA6 4263
ETF1 4300
PSMC2 4457
PSMB2 4680
SRGAP3 4783
UBC 4874
PSMB8 5433
PSMD8 5474
NRP1 5491
PSMD2 5544
RPL3L 5700
PSMD12 5714
PSMC1 5778
PAK2 5789
PSMD5 6029
RPL26L1 6187
PSMD1 6354
PSME3 6605
ENAH 6964
PSMD11 7057
CASC3 7085
CDC42 7337
ELOB 7511
ELOC 7671
SEM1 7739
PSMB7 7941
CAP1 8422
PFN1 8600
PSMB5 8625
PSMA7 8719
PSMD6 8745
RHOA 8752
SOS2 8927
PSMD9 9005
PSMB6 9262
SRGAP1 9634
SLIT1 9684
VASP 9774
PSMB3 9902
EIF4G1 9922
PSMD4 10295
ZSWIM8 10415
PAK1 10704
RAC1 10907
SRGAP2 11133
MYO9B 11181
PRKACA 11578


Cell Cycle

Cell Cycle
153
set Cell Cycle
setSize 623
pANOVA 8.8e-11
s.dist -0.152
p.adjustANOVA 3.24e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
CDC14A -9861
NPM1 -9836
DKC1 -9835
NDC1 -9817
MCM3 -9769
POLD2 -9742
RBL2 -9700
POLA1 -9660
RPA1 -9657
NUP35 -9626
MIS18A -9606
AJUBA -9543
CEP76 -9542
TUBB4A -9524
STN1 -9499
CDC25B -9481
BUB3 -9475
RAD1 -9471
TFDP2 -9444
NUP88 -9430

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CDC14A -9861.0
NPM1 -9836.0
DKC1 -9835.0
NDC1 -9817.0
MCM3 -9769.0
POLD2 -9742.0
RBL2 -9700.0
POLA1 -9660.0
RPA1 -9657.0
NUP35 -9626.0
MIS18A -9606.0
AJUBA -9543.0
CEP76 -9542.0
TUBB4A -9524.0
STN1 -9499.0
CDC25B -9481.0
BUB3 -9475.0
RAD1 -9471.0
TFDP2 -9444.0
NUP88 -9430.0
MYC -9418.0
CHMP7 -9399.0
ANAPC1 -9394.0
SPDL1 -9307.0
MCM6 -9297.0
CCND2 -9246.0
CENPH -9233.0
FBXO5 -9228.0
OPTN -9165.0
HSP90AB1 -9152.0
WRN -9097.0
OFD1 -9086.0
MIS12 -9038.0
CEP78 -8971.0
POLE3 -8924.0
CUL1 -8878.0
NCAPD3 -8857.0
NUP107 -8801.0
SEH1L -8792.0
CHTF18 -8785.0
MLH3 -8776.0
AKT3 -8761.0
CEP72 -8753.0
ITGB3BP -8742.0
RPS27A -8722.0
NUP160 -8699.0
RFC3 -8694.0
LIG1 -8618.0
TP53 -8613.0
HAUS3 -8547.0
CEP57 -8544.0
CDK4 -8539.0
MAD2L1 -8491.0
DBF4 -8484.0
TUBG2 -8465.0
KIF2A -8455.0
CEP70 -8423.0
ODF2 -8342.0
CENPM -8299.0
PRIM1 -8268.0
RPS27 -8260.0
VRK1 -8230.0
RANGAP1 -8224.0
GINS4 -8200.0
POLR2D -8160.0
ORC2 -8097.0
ORC5 -8089.0
CDC23 -8076.0
RPA3 -8069.0
DYNLL2 -8015.0
CTC1 -8006.0
LIN9 -8001.0
PPP2R2D -7986.0
SET -7950.0
SHQ1 -7860.0
RUVBL1 -7856.0
NUP43 -7792.0
RAD17 -7742.0
RFC4 -7736.0
MCM7 -7720.0
CENPQ -7689.0
PPP2R5C -7679.0
DSCC1 -7671.0
E2F6 -7656.0
NUP155 -7633.0
MCM4 -7627.0
PSMB9 -7625.0
SFI1 -7605.0
RAN -7577.0
ORC3 -7568.0
MCM2 -7557.0
CSNK1E -7527.0
ATM -7513.0
HAUS6 -7511.0
CDKN1B -7508.0
MZT2A -7471.0
NINL -7404.0
BORA -7395.0
SYNE2 -7382.0
RBBP7 -7322.0
NCAPH2 -7314.0
NUP188 -7295.0
SMC2 -7215.0
ANAPC16 -7186.0
PCBP4 -7141.0
FEN1 -7122.0
HAUS5 -7120.0
TUBA3D -7118.0
NUP205 -7051.0
PLK4 -7001.0
BTRC -6984.0
MDC1 -6961.0
CENPJ -6905.0
MZT1 -6883.0
PCNA -6841.0
PRKAR2B -6807.0
SGO2 -6783.0
MCM10 -6777.0
RBL1 -6718.0
GAR1 -6696.0
TP53BP1 -6695.0
LPIN2 -6679.0
POLE2 -6659.0
STAG1 -6554.0
ESCO1 -6521.0
PSME1 -6399.0
SUN2 -6393.0
NDC80 -6377.0
PSMA5 -6362.0
GORASP2 -6358.0
PPP2R5E -6283.0
H2BC9 -6264.0
RAD21 -6258.0
PCNT -6252.0
BRIP1 -6240.0
POLA2 -6222.0
CEP290 -6203.0
CENPC -6141.0
MCM8 -6138.0
TERT -6124.0
SMARCA5 -6114.0
ARPP19 -6085.0
POM121C -6074.0
YWHAQ -6039.0
CHEK1 -6036.0
ZWINT -6019.0
MCPH1 -5944.0
PSMC5 -5909.0
H2AZ2 -5901.0
PHF20 -5876.0
POT1 -5841.0
TYMS -5813.0
BUB1B -5801.0
SKP1 -5791.0
PPP2R3B -5780.0
BUB1 -5773.0
ANKRD28 -5772.0
CENPT -5770.0
SMC3 -5758.0
NHP2 -5747.0
RRM2 -5738.0
ORC4 -5692.0
NUP133 -5674.0
PRKCA -5667.0
PRIM2 -5653.0
MNAT1 -5650.0
CDC45 -5643.0
CDK1 -5568.0
SRC -5527.0
TUBGCP6 -5515.0
RFC1 -5493.0
LIN52 -5480.0
CDC6 -5479.0
LPIN1 -5449.0
CENPL -5433.0
SMC4 -5416.0
NUP54 -5340.0
E2F5 -5304.0
LMNA -5294.0
TUBB -5289.0
AHCTF1 -5169.0
ORC1 -5158.0
NEK7 -5144.0
EMD -5130.0
POLR2B -5111.0
EML4 -5100.0
HSP90AA1 -5083.0
RAD9A -5073.0
ZWILCH -5036.0
CDK5RAP2 -5035.0
RHNO1 -4965.0
MRE11 -4960.0
TERF2 -4926.0
TUBB1 -4868.0
MYBL2 -4826.0
HERC2 -4759.0
WEE1 -4746.0
TUBGCP5 -4715.0
CLASP2 -4711.0
RBBP4 -4658.0
CENPK -4642.0
CDK6 -4636.0
RPA2 -4620.0
PDS5A -4597.0
PSMD10 -4578.0
DIDO1 -4566.0
MZT2B -4548.0
MAX -4483.0
NUP153 -4433.0
BLM -4432.0
KNTC1 -4400.0
CENPN -4391.0
SUN1 -4385.0
NUP210 -4373.0
PSMA3 -4338.0
BANF1 -4324.0
EXO1 -4293.0
ALMS1 -4279.0
NUF2 -4277.0
NUDC -4267.0
NCAPH -4213.0
XPO1 -4204.0
SYCE1 -4146.0
CEP131 -4139.0
TPR -4127.0
TOP2A -4125.0
WRAP53 -4086.0
RAD50 -4065.0
LCMT1 -4047.0
CDT1 -4032.0
CC2D1B -4029.0
DNA2 -4017.0
ATRX -4015.0
GINS3 -3998.0
RFC5 -3986.0
SYCE2 -3975.0
ACD -3963.0
AKAP9 -3928.0
ANAPC5 -3910.0
POLR2K -3902.0
CDCA5 -3870.0
PHLDA1 -3863.0
LEMD3 -3858.0
TERF1 -3813.0
LIN54 -3805.0
CCND1 -3717.0
CDK2 -3694.0
DAXX -3631.0
CKS1B -3620.0
POLR2H -3611.0
PSME2 -3570.0
TNPO1 -3493.0
HMMR -3479.0
SKA2 -3420.0
DSN1 -3386.0
GINS2 -3279.0
LPIN3 -3221.0
BRCA2 -3186.0
NUP93 -3163.0
UBE2N -3154.0
RANBP2 -3109.0
RCC1 -3085.0
DYRK1A -3079.0
RSF1 -2933.0
PPP2R1B -2904.0
TUBGCP4 -2883.0
ZW10 -2813.0
CCNE1 -2791.0
ATR -2784.0
CEP41 -2740.0
CENPU -2720.0
NUP42 -2718.0
SMC1B -2687.0
CDCA8 -2626.0
CENPA -2615.0
TUBA8 -2569.0
POLR2C -2566.0
FOXM1 -2561.0
CDC27 -2558.0
CDC25A -2547.0
CCNB1 -2524.0
TPX2 -2523.0
NCAPG -2509.0
UBB -2442.0
STAG2 -2436.0
UBE2V2 -2394.0
NME7 -2347.0
CETN2 -2342.0
CEP135 -2331.0
POM121 -2295.0
CCNA1 -2231.0
PDS5B -2230.0
H2BU1 -2206.0
CEP250 -2187.0
ANAPC2 -2172.0
CENPF -2144.0
UBE2C -2114.0
ESCO2 -2104.0
PSMA2 -2032.0
PSMB1 -1960.0
CDC20 -1938.0
TOPBP1 -1834.0
H2AC6 -1829.0
NSD2 -1745.0
CCNA2 -1727.0
NUP85 -1717.0
RAD51 -1636.0
CDC16 -1623.0
POLR2I -1599.0
ATRIP -1520.0
HAUS7 -1485.0
POLE -1479.0
VPS4A -1442.0
UBA52 -1437.0
NUP37 -1424.0
KIF20A -1419.0
WAPL -1381.0
PPP2R2A -1333.0
PCM1 -1329.0
NUP50 -1242.0
NEDD1 -1240.0
POLE4 -1186.0
PPP6C -1168.0
TERF2IP -1108.0
PSME4 -1087.0
CNTRL -1047.0
DYNC1H1 -1040.0
HJURP -980.0
GINS1 -976.0
MSH4 -967.0
GTSE1 -888.0
CABLES1 -831.0
CKAP5 -824.0
HAUS8 -804.0
SMC1A -662.0
YWHAZ -647.0
INCENP -614.0
ESPL1 -556.0
BARD1 -534.0
SKP2 -520.0
CHTF8 -503.0
CHMP2B -392.0
PKMYT1 -382.0
PSMB10 -372.0
BIRC5 -333.0
PPP6R3 -249.0
CLSPN -178.0
PSMA4 -118.0
NCAPG2 -117.0
USO1 -110.0
KPNB1 -109.0
E2F1 -108.0
NUMA1 -102.0
CDC26 6.0
PMF1 52.0
KIF18A 102.0
SPC24 111.0
HAUS2 112.0
CCP110 126.0
RNF168 130.0
ANAPC10 141.0
NUP98 175.0
RNF8 199.0
SYCP2 214.0
PSMD14 225.0
UBE2E1 291.0
NEK2 345.0
NUP62 395.0
BLZF1 483.0
H2BC15 524.0
UBE2I 587.0
AAAS 627.0
POLD1 646.0
NBN 709.0
BABAM1 735.0
AURKB 781.0
VRK2 793.0
CDC7 815.0
PRDM9 821.0
NEK9 870.0
ANAPC4 875.0
HAUS1 943.0
TUBG1 982.0
REC8 1021.0
TEN1 1027.0
PSMF1 1056.0
NCAPD2 1097.0
KIF2C 1104.0
DYNC1I1 1191.0
NIPBL 1196.0
CENPI 1203.0
FBXW11 1218.0
MDM4 1276.0
MCM5 1277.0
CDC25C 1278.0
CEP192 1304.0
CLASP1 1310.0
SYNE1 1370.0
PSMC4 1389.0
PSMD7 1547.0
PIF1 1616.0
FZR1 1793.0
CENPE 1952.0
YWHAB 2038.0
PTTG1 2074.0
KAT5 2121.0
PSMC3 2182.0
KNL1 2231.0
TK1 2257.0
UBE2S 2306.0
HUS1 2327.0
CDK11B 2328.0
HDAC1 2347.0
RUVBL2 2364.0
FKBP6 2430.0
PPME1 2469.0
GSK3B 2520.0
PPP2R5D 2555.0
SFN 2567.0
TUBA4B 2576.0
SSNA1 2600.0
MLH1 2650.0
MSH5 2658.0
MIS18BP1 2725.0
CHEK2 2738.0
ANAPC7 2814.0
PPP1CB 2847.0
PPP1CC 2943.0
H2AZ1 2960.0
PLK1 2972.0
TUBA1C 3008.0
CENPP 3032.0
HSPA2 3048.0
SKA1 3064.0
CDKN1A 3132.0
SPAST 3167.0
DYNLL1 3185.0
AURKA 3271.0
H2BC11 3290.0
FKBPL 3318.0
ANKLE2 3334.0
MAD1L1 3435.0
POLR2L 3450.0
PSMA1 3451.0
PSMC6 3483.0
CEP164 3597.0
SUMO1 3612.0
BRCC3 3628.0
SGO1 3635.0
MAPRE1 3656.0
RBX1 3691.0
CCNE2 3704.0
PSMB4 3707.0
PAFAH1B1 3738.0
PSMD13 3770.0
JAK2 3783.0
H2BC17 3795.0
PHF8 3823.0
CCNB2 3892.0
RAB8A 3907.0
TUBA4A 3909.0
ABL1 4039.0
ERCC6L 4040.0
PSMD3 4177.0
H2BC4 4239.0
PSMA6 4263.0
CSNK2A2 4323.0
TFDP1 4357.0
H2BC5 4435.0
PPP1R12A 4439.0
PSMC2 4457.0
ANAPC11 4464.0
RAD51C 4501.0
PSMC3IP 4521.0
CDKN2A 4560.0
PPP2R1A 4593.0
RMI2 4605.0
NDE1 4671.0
PSMB2 4680.0
CDKN2D 4820.0
RFC2 4835.0
RCC2 4844.0
UBC 4874.0
PPP2CA 4882.0
CDK7 4908.0
RAE1 5040.0
KIF23 5122.0
BRCA1 5214.0
CDK11A 5232.0
POLR2E 5238.0
GMNN 5280.0
LIN37 5346.0
PPP2CB 5377.0
LBR 5389.0
AKT2 5390.0
PSMB8 5433.0
E2F4 5439.0
PSMD8 5474.0
DHFR 5520.0
MDM2 5532.0
PSMD2 5544.0
POLR2G 5695.0
PSMD12 5714.0
DYNC1I2 5729.0
POLR2F 5738.0
PSMC1 5778.0
CENPO 5838.0
RBBP8 5902.0
TINF2 5948.0
MASTL 5976.0
PSMD5 6029.0
H2BC12 6101.0
AKT1 6133.0
TAOK1 6148.0
H2BC21 6180.0
PSMD1 6354.0
POLR2A 6387.0
ENSA 6452.0
CSNK2B 6563.0
CEP63 6566.0
CDKN2C 6579.0
TUBB4B 6583.0
OIP5 6593.0
PSME3 6605.0
H3C15 6611.5
TUBA1B 6662.0
STAG3 6680.0
CHMP4A 6691.0
CHMP6 6694.0
E2F3 6700.0
CHMP3 6707.0
SEC13 6793.0
CENPW 6896.0
RMI1 7005.0
PSMD11 7057.0
PPP1R12B 7089.0
PRKCB 7102.0
CCNH 7145.0
RTEL1 7274.0
CEP152 7449.0
ZNF385A 7452.0
CSNK1D 7458.0
PPP2R5A 7512.0
FBXL18 7571.0
CNEP1R1 7586.0
H3-3A 7624.0
NUP58 7628.0
IST1 7650.0
TUBA1A 7690.0
SEM1 7739.0
CTDNEP1 7768.0
TUBGCP2 7795.0
DYNC1LI1 7881.0
DCTN3 7885.0
PSMB7 7941.0
POLR2J 7983.0
CSNK2A1 7984.0
RAB2A 8033.0
DYNC1LI2 8092.0
YWHAH 8129.0
GOLGA2 8366.0
MAU2 8374.0
NEK6 8427.0
ORC6 8542.0
LEMD2 8556.0
YWHAE 8584.0
NSL1 8609.0
PSMB5 8625.0
RAD9B 8706.0
PSMA7 8719.0
SIRT2 8720.0
SDCCAG8 8730.0
TMPO 8743.0
PSMD6 8745.0
B9D2 8773.0
H2AC20 8783.0
TUBGCP3 8804.0
EP300 8816.0
TOP3A 8956.0
PTK6 8980.0
PSMD9 9005.0
PIAS4 9149.0
UBE2D1 9204.0
DCTN1 9214.0
SYCP1 9247.0
CDKN2B 9248.0
PSMB6 9262.0
TUBB6 9304.0
RAB1B 9447.0
CCND3 9462.0
NDEL1 9493.0
TUBB3 9545.0
MAPK3 9636.0
RB1 9765.0
HDAC8 9800.0
UIMC1 9837.0
YWHAG 9892.0
PSMB3 9902.0
RAB1A 9919.0
ANAPC15 9931.0
ACTR1A 10067.0
NUP214 10124.0
KMT5A 10179.0
PSMD4 10295.0
TUBB2A 10298.0
POLD4 10344.0
DCTN2 10458.0
CDKN1C 10502.0
PPP2R5B 10579.0
CHMP4B 10624.0
CHMP2A 10625.0
CLIP1 10667.0
NOP10 10793.0
MAPK1 10847.0
LYN 10893.0
GORASP1 10996.0
LMNB1 11079.0
E2F2 11246.0
HAUS4 11267.0
POLD3 11274.0
SYCP3 11298.0
PRKACA 11578.0
H2AJ 11606.0


tRNA processing

tRNA processing
1359
set tRNA processing
setSize 134
pANOVA 1.13e-09
s.dist -0.305
p.adjustANOVA 4.06e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
NDC1 -9817
MT-TP -9673
NUP35 -9626
RPP40 -9619
ALKBH8 -9608
NUP88 -9430
TRMT11 -9107
TYW1 -9075
METTL1 -8884
PUS7 -8881
TP53RK -8827
NUP107 -8801
SEH1L -8792
NUP160 -8699
TRMT10C -8270
TSEN54 -8093
TYW3 -7825
NUP43 -7792
TRMT61B -7694
NUP155 -7633

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NDC1 -9817
MT-TP -9673
NUP35 -9626
RPP40 -9619
ALKBH8 -9608
NUP88 -9430
TRMT11 -9107
TYW1 -9075
METTL1 -8884
PUS7 -8881
TP53RK -8827
NUP107 -8801
SEH1L -8792
NUP160 -8699
TRMT10C -8270
TSEN54 -8093
TYW3 -7825
NUP43 -7792
TRMT61B -7694
NUP155 -7633
RPP25 -7624
RAN -7577
LCMT2 -7516
QTRT1 -7397
NUP188 -7295
TRMT13 -7202
RPP30 -7173
TPRKB -7143
TSEN15 -7067
TSEN2 -7057
NUP205 -7051
TRMT61A -7025
EPRS1 -6849
MT-ND2 -6727
RPP38 -6534
MT-RNR1 -6484
XPOT -6407
ADAT2 -6386
THG1L -6318
POM121C -6074
MT-ND1 -5852
DDX1 -5751
NUP133 -5674
MTO1 -5635
FAM98B -5439
CDKAL1 -5422
NUP54 -5340
LAGE3 -5316
POP5 -5173
PUS1 -5165
THADA -5123
C2orf49 -4992
TRMT5 -4833
POP1 -4584
GTPBP3 -4453
NUP153 -4433
NUP210 -4373
MT-CO3 -4247
OSGEP -4189
CTU2 -4179
TPR -4127
WDR4 -3834
RTRAF -3817
FTSJ1 -3726
ELAC2 -3686
PRORP -3614
TRMT1 -3450
MT-ND6 -3405
MT-ND5 -3188
NUP93 -3163
RANBP2 -3109
MT-ND3 -2969
TRMT44 -2946
CSTF2 -2788
NUP42 -2718
TRNT1 -2576
RPP14 -2433
CPSF4 -2319
POM121 -2295
TRMU -2286
MT-CYB -2095
ADAT1 -1762
NUP85 -1717
TRIT1 -1701
NUP37 -1424
NUP50 -1242
TRMT12 -949
POP4 -441
TRMT112 -370
RPP21 -200
MT-RNR2 -141
MT-ATP6 36
NUP98 175
PUS3 349
NUP62 395
MT-CO1 507
TYW5 618
AAAS 627
MT-CO2 729
RTCB 848
URM1 899
POP7 963
MT-TF 1008
MT-TS1 1223
MT-ATP8 1944
NSUN6 2287
QTRT2 3042
MT-ND4L 3155
MT-TE 3244
MT-TY 3249
CTU1 3335
TRDMT1 3457
CLP1 3627
MT-TA 3873
MT-TV 4515
MT-TN 4608
CPSF1 4828
MT-TL1 5025
RAE1 5040
NSUN2 5093
TRMT6 5486
MT-TC 5567
MT-ND4 5850
DUS2 6141
HSD17B10 6466
SEC13 6793
ADAT3 6884
TRMT10A 7232
TSEN34 7554
NUP58 7628
ZBTB8OS 9012
NUP214 10124
RPPH1 11164
TRMT9B 11352


Metabolism of amino acids and derivatives

Metabolism of amino acids and derivatives
637
set Metabolism of amino acids and derivatives
setSize 324
pANOVA 1.23e-09
s.dist -0.196
p.adjustANOVA 4.29e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
GLS -9763
RPL3 -9701
RPS2 -9635
SARDH -9609
CARNMT1 -9536
SRM -9476
BCKDHB -9431
RIMKLB -9401
RPL14 -9390
RPL23A -9382
RPL5 -9359
ENOPH1 -9288
RPS3A -9257
GAMT -9243
DBH -9200
RPS6 -9170
RPL7 -9134
ALDH18A1 -9111
AZIN2 -9093
RPL4 -9065

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GLS -9763
RPL3 -9701
RPS2 -9635
SARDH -9609
CARNMT1 -9536
SRM -9476
BCKDHB -9431
RIMKLB -9401
RPL14 -9390
RPL23A -9382
RPL5 -9359
ENOPH1 -9288
RPS3A -9257
GAMT -9243
DBH -9200
RPS6 -9170
RPL7 -9134
ALDH18A1 -9111
AZIN2 -9093
RPL4 -9065
AASS -9048
RPL22 -8915
LARS1 -8879
SERINC5 -8869
RPS3 -8856
RPS25 -8832
RPL21 -8773
IL4I1 -8741
PPM1K -8728
RPS27A -8722
GLS2 -8711
IARS1 -8710
RPS5 -8698
RPLP0 -8691
RPL12 -8689
RPL13A -8688
ACADSB -8656
LIPT1 -8557
RPL6 -8498
RPL34 -8489
RPS20 -8476
RPL17 -8462
RPL27A -8420
RPS12 -8401
MTR -8347
RPS14 -8337
RPS23 -8334
RPL10 -8318
RPS27 -8260
RPLP2 -8255
SLC5A5 -8146
RPL36A -8130
RPS7 -8047
RPL35A -8046
RPL10A -7989
RPL29 -7954
RPL11 -7928
RPL32 -7914
RPS15A -7912
HDC -7874
RPL22L1 -7828
RPL30 -7783
RPL18 -7781
RPL35 -7710
LIPT2 -7666
RPL26 -7648
KARS1 -7645
RPS4X -7636
RPS10 -7629
RPL24 -7626
PSMB9 -7625
RPS16 -7617
RPL18A -7609
RPL31 -7521
RPL9 -7451
RPL15 -7380
RPS13 -7375
GOT2 -7352
RPL7A -7296
RPS18 -7288
SRR -7275
GLDC -7239
RPS8 -7161
RPS17 -7134
IDO1 -7100
SEPSECS -7064
RPL19 -7006
CARNS1 -6964
ODC1 -6952
RPL23 -6933
FTCD -6907
EPRS1 -6849
RPS29 -6791
DARS1 -6758
RPS11 -6742
RPS21 -6706
IVD -6704
HGD -6701
MCCC1 -6687
RPL37 -6660
RPL38 -6589
MTAP -6466
SLC25A10 -6451
RPS28 -6429
SARS1 -6425
PSME1 -6399
PSMA5 -6362
MCCC2 -6350
RPL36 -6343
TPO -6330
RPL8 -6274
ASNS -6196
NAALAD2 -6143
TSTD1 -6139
SLC25A15 -6115
SECISBP2 -6069
RPL27 -6068
RPL41 -6065
PSMC5 -5909
GCDH -5903
ADO -5897
SCLY -5892
AGMAT -5871
RPL39 -5790
RPS19 -5616
NQO1 -5594
TPH1 -5593
RPL13 -5550
RPS26 -5524
RPS15 -5342
RPS24 -5310
EEFSEC -5238
HYKK -5170
AIMP1 -5088
ECHS1 -5038
SERINC4 -4973
PAOX -4912
CKMT2 -4873
RPL37A -4774
PSMD10 -4578
RPSA -4559
PNMT -4452
PSMA3 -4338
DUOX1 -4314
PYCR2 -4312
GCAT -4290
RPL36AL -4148
DBT -4122
GOT1 -4033
RPLP1 -3887
ACAT1 -3857
IDO2 -3724
PSME2 -3570
DLAT -3559
DIO1 -3369
NDUFAB1 -3353
GPT -3326
AMD1 -3233
PSTK -3075
QARS1 -3062
AMT -2938
HIBADH -2864
AHCY -2734
AIMP2 -2623
LIAS -2591
PDHA1 -2478
DLST -2268
OAZ3 -2262
ALDH9A1 -2258
PYCR1 -2248
CTH -2211
PSMA2 -2032
KYAT1 -1982
PSMB1 -1960
RPL28 -1952
INMT -1946
SMS -1933
PHGDH -1637
ASRGL1 -1635
PDHB -1542
UBA52 -1437
GATM -1400
KYAT3 -1271
PDHX -1200
SLC25A12 -1156
RARS1 -1110
PSME4 -1087
FAU -1029
AMDHD1 -688
SLC7A5 -634
NMRAL1 -600
PSMB10 -372
GCSH -266
BCAT2 -167
SHMT1 -133
PSMA4 -118
RPL39L -69
PSMD14 225
SERINC1 447
GRHPR 527
DDO 614
MRI1 650
QDPR 664
ACMSD 867
GLUD1 886
RIDA 966
AZIN1 1024
PSMF1 1056
ALDH6A1 1240
PRODH 1274
PSMC4 1389
RPS4Y1 1461
PSMD7 1547
ALDH7A1 1576
HIBCH 1859
RIMKLA 2107
ASPA 2109
PSMC3 2182
EEF1E1 2209
RPS9 2392
SLC44A1 2702
KMO 2766
RPS27L 2784
MTRR 2810
IYD 2968
CKB 3074
TST 3427
PSMA1 3451
SLC6A8 3456
PSMC6 3483
SMOX 3640
PSMB4 3707
ADI1 3762
PSMD13 3770
ACAD8 4168
PSMD3 4177
SLC25A13 4207
SLC25A21 4230
PXMP2 4245
PSMA6 4263
PSMC2 4457
PSMB2 4680
MPST 4929
TXN2 5240
PSPH 5275
SDS 5340
PSMB8 5433
PSMD8 5474
PSMD2 5544
SERINC3 5648
RPL3L 5700
PSMD12 5714
PSMC1 5778
APIP 5931
AANAT 6005
PSMD5 6029
NAGS 6115
RPL26L1 6187
ARG2 6273
PSMD1 6354
HSD17B10 6466
AUH 6519
PSME3 6605
BCKDHA 6607
SLC6A12 6849
GADL1 6870
DLD 7032
PSMD11 7057
GPT2 7118
SLC3A2 7229
SEPHS2 7242
TPH2 7294
GNMT 7343
SEM1 7739
PSMB7 7941
HNMT 8194
TXNRD1 8216
SLC36A4 8324
OAT 8382
PSAT1 8484
HAL 8579
DHTKD1 8620
PSMB5 8625
PSMA7 8719
PSMD6 8745
OGDH 8941
PSMD9 9005
ARG1 9013
PIPOX 9031
OAZ1 9164
HAAO 9229
PSMB6 9262
CRYM 9288
PAPSS1 9661
MARS1 9700
SDSL 9739
SLC25A44 9744
FAH 9762
ETHE1 9773
PSMB3 9902
CKM 9978
TMLHE 10056
SERINC2 10128
KYNU 10203
HPD 10222
PSMD4 10295
SAT1 10483
CSAD 10707
ALDH4A1 10756
GSR 10772
PCBD1 10783
PHYKPL 10806
CBSL 10872
CBS 10976
OAZ2 11004
CHDH 11095
GSTZ1 11135
BCKDK 11137
ASL 11143
BCAT1 11221
GLUL 11386
SUOX 11678
AFMID 11725
PAPSS2 11736


Processing of Capped Intron-Containing Pre-mRNA

Processing of Capped Intron-Containing Pre-mRNA
853
set Processing of Capped Intron-Containing Pre-mRNA
setSize 238
pANOVA 6.69e-09
s.dist -0.218
p.adjustANOVA 2.28e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
NDC1 -9817
THOC3 -9796
NUP35 -9626
NUP88 -9430
RBMX -9321
HSPA8 -9166
HNRNPA0 -9015
GCFC2 -8941
SNRPN -8838
NUP107 -8801
SEH1L -8792
SF3B3 -8790
NUP160 -8699
WBP11 -8686
NUDT21 -8636
NXT1 -8554
PRPF19 -8548
SNRNP40 -8492
NCBP2 -8212
POLR2D -8160

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NDC1 -9817
THOC3 -9796
NUP35 -9626
NUP88 -9430
RBMX -9321
HSPA8 -9166
HNRNPA0 -9015
GCFC2 -8941
SNRPN -8838
NUP107 -8801
SEH1L -8792
SF3B3 -8790
NUP160 -8699
WBP11 -8686
NUDT21 -8636
NXT1 -8554
PRPF19 -8548
SNRNP40 -8492
NCBP2 -8212
POLR2D -8160
LSM5 -8094
SRSF5 -7996
SNU13 -7987
HNRNPR -7882
SRSF11 -7838
NUP43 -7792
SRSF10 -7755
PPIH -7717
NUP155 -7633
FYTTD1 -7487
HNRNPA1 -7469
CSTF1 -7377
NUP188 -7295
HNRNPA3 -7261
PPIL1 -7166
PRPF6 -7127
SRSF6 -7099
NUP205 -7051
RNPS1 -7032
SNRPE -6979
SF3A3 -6863
PLRG1 -6780
SNRPF -6725
SF3B1 -6469
PRPF8 -6374
RBM17 -6331
PDCD7 -6173
POM121C -6074
SNRNP200 -6070
ELAVL1 -5954
SF3A1 -5895
BCAS2 -5731
LSM4 -5680
NUP133 -5674
SNRNP48 -5596
DHX9 -5556
SRSF3 -5528
LSM7 -5504
PPWD1 -5498
SNRNP70 -5483
NUP54 -5340
POLR2B -5111
SF3A2 -5104
SRSF2 -5095
PPIE -5064
THOC1 -5006
SNRPA1 -4867
SLBP -4830
LSM8 -4763
SNRPD2 -4757
MTREX -4734
SRSF7 -4657
HNRNPH1 -4617
U2SURP -4531
DHX15 -4502
NUP153 -4433
SNRPD3 -4404
NUP210 -4373
PTBP1 -4302
TPR -4127
CSTF2T -4089
CWC22 -4076
MAGOHB -4045
FIP1L1 -3955
POLR2K -3902
DDX5 -3820
PPIL4 -3815
ZC3H11A -3770
SNRPD1 -3757
POLR2H -3611
CRNKL1 -3606
SNRPB -3546
ALYREF -3518
PRPF38A -3334
METTL14 -3289
SRRT -3284
NUP93 -3163
RANBP2 -3109
SRSF1 -3108
UPF3B -3065
RBM8A -2980
CHERP -2861
METTL3 -2808
CSTF2 -2788
NUP42 -2718
POLR2C -2566
PPIL3 -2544
HNRNPD -2497
SNRPB2 -2429
LSM2 -2392
DDX42 -2376
CPSF4 -2319
PQBP1 -2305
POM121 -2295
PCBP2 -2170
PRPF31 -2159
DNAJC8 -2118
SRRM1 -2111
MAGOH -1931
SLU7 -1726
NUP85 -1717
POLR2I -1599
CCAR1 -1587
RNPC3 -1544
ZCRB1 -1532
ISY1 -1477
CHTOP -1452
NUP37 -1424
THOC2 -1413
DHX16 -1369
PRPF3 -1341
PUF60 -1289
HNRNPF -1277
NUP50 -1242
SNRNP27 -1210
NCBP1 -1125
SF1 -1103
HNRNPUL1 -917
EIF4A3 -915
CWC27 -901
HNRNPU -781
PHF5A -696
DDX39A -651
SNRPC -613
XAB2 -562
WTAP -501
YBX1 -423
PRPF40A -396
FUS -263
WDR33 -253
LSM3 21
NUP98 175
TRA2B 372
NUP62 395
THOC6 473
CWC15 544
USP39 611
AAAS 627
SNRNP25 671
SF3B5 672
DDX46 825
U2AF2 883
SYF2 941
U2AF1L4 985
DHX38 1001
RBM22 1158
AQR 1282
CDC5L 1283
THOC7 1391
SNW1 1506
ZRSR2 1562
RBM5 1791
SMNDC1 1892
SARNP 1972
DDX39B 2041
PAPOLA 2096
EIF4E 2104
WBP4 2342
PCF11 2498
PABPN1 2573
SF3B2 2587
HNRNPK 2644
SF3B6 2791
PPIL6 2992
PRPF4 3084
SRRM2 3184
HNRNPM 3201
HNRNPC 3313
CDC40 3360
SNRPA 3417
POLR2L 3450
CWC25 3513
CLP1 3627
TFIP11 3706
U2AF1 3739
SNRPG 3835
SF3B4 3986
GPKOW 4101
PRCC 4237
SART1 4376
SYMPK 4502
CTNNBL1 4575
CPSF2 4583
CPSF1 4828
CPSF7 4872
RAE1 5040
PCBP1 5106
POLR2E 5238
GTF2F2 5263
LSM6 5419
BUD31 5489
GTF2F1 5494
GLE1 5575
POLR2G 5695
POLR2F 5738
HNRNPL 5742
DDX23 6081
CSTF3 6324
HNRNPA2B1 6339
POLR2A 6387
TXNL4A 6590
CPSF3 6658
HNRNPH2 6735
SUGP1 6788
SEC13 6793
SRSF4 7078
CASC3 7085
NUP58 7628
POLR2J 7983
NXF1 8049
SNRNP35 8105
EFTUD2 8476
CD2BP2 9074
SRSF9 9246
POLDIP3 10060
THOC5 10063
NUP214 10124
ZMAT5 10301


CD22 mediated BCR regulation

CD22 mediated BCR regulation
121
set CD22 mediated BCR regulation
setSize 59
pANOVA 6.94e-09
s.dist -0.436
p.adjustANOVA 2.31e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
IGKV3-11 -9443
IGLV6-57 -8979
CD79A -8733
IGLV2-14 -8599
IGHV3-33 -8574
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
IGKV3-15 -7683
IGHV1-69 -7589
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
CD79B -7082
CD22 -6705
IGHV3-53 -6692
IGHV4-34 -6614
IGHV2-5 -6583
IGHV3-48 -5881

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IGKV3-11 -9443
IGLV6-57 -8979
CD79A -8733
IGLV2-14 -8599
IGHV3-33 -8574
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
IGKV3-15 -7683
IGHV1-69 -7589
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
CD79B -7082
CD22 -6705
IGHV3-53 -6692
IGHV4-34 -6614
IGHV2-5 -6583
IGHV3-48 -5881
IGLC7 -5764
IGLV3-27 -5637
IGHV3-23 -5636
IGHV1-2 -5526
IGLV1-51 -5296
IGKC -5232
IGHV3-7 -5228
IGHD -5224
IGHM -5149
IGLC2 -5138
IGKV3-20 -5082
IGKV1-33 -4953
IGHV4-39 -4884
IGHV3-30 -4685
IGLV1-47 -4485
IGKV1-12 -4392
IGKV2-28 -4281
IGLC1 -4280
IGHV2-70 -4223
IGHV3-11 -3626
IGHV1-46 -3558
IGLV1-40 -3024
IGKV2-30 -2958
IGKV1-17 -2929
IGHV4-59 -2340
IGLV3-25 -1935
IGHV3-13 -1600
IGLV1-44 -1090
IGKV2D-28 -728
IGLC3 -403
IGKV3D-20 -305
IGLV2-23 1244
IGKV5-2 3051
IGLV2-11 3601
IGKV1D-39 3771
IGLV7-43 7123
IGKV1-39 9771
LYN 10893
PTPN6 11254


Activation of the pre-replicative complex

Activation of the pre-replicative complex
50
set Activation of the pre-replicative complex
setSize 32
pANOVA 1.2e-08
s.dist -0.582
p.adjustANOVA 3.89e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
MCM3 -9769
POLA1 -9660
RPA1 -9657
MCM6 -9297
POLE3 -8924
DBF4 -8484
PRIM1 -8268
ORC2 -8097
ORC5 -8089
RPA3 -8069
MCM7 -7720
MCM4 -7627
ORC3 -7568
MCM2 -7557
MCM10 -6777
POLE2 -6659
POLA2 -6222
MCM8 -6138
ORC4 -5692
PRIM2 -5653

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MCM3 -9769
POLA1 -9660
RPA1 -9657
MCM6 -9297
POLE3 -8924
DBF4 -8484
PRIM1 -8268
ORC2 -8097
ORC5 -8089
RPA3 -8069
MCM7 -7720
MCM4 -7627
ORC3 -7568
MCM2 -7557
MCM10 -6777
POLE2 -6659
POLA2 -6222
MCM8 -6138
ORC4 -5692
PRIM2 -5653
CDC45 -5643
CDC6 -5479
ORC1 -5158
RPA2 -4620
CDT1 -4032
CDK2 -3694
POLE -1479
POLE4 -1186
CDC7 815
MCM5 1277
GMNN 5280
ORC6 8542


Translocation of ZAP-70 to Immunological synapse

Translocation of ZAP-70 to Immunological synapse
1278
set Translocation of ZAP-70 to Immunological synapse
setSize 24
pANOVA 1.86e-08
s.dist -0.663
p.adjustANOVA 5.9e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
TRBV12-3 -9724
CD247 -9497
LCK -9485
HLA-DQA2 -9407
TRAV19 -9396
CD3E -9378
TRAC -9330
CD3G -9125
HLA-DQB2 -9021
CD3D -8747
TRBC1 -8666
ZAP70 -8662
TRAV29DV5 -8326
TRAV8-4 -7607
HLA-DPB1 -7109
TRBV7-9 -6741
HLA-DRA -6613
HLA-DPA1 -5854
CD4 -4882
HLA-DQA1 -1465

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TRBV12-3 -9724
CD247 -9497
LCK -9485
HLA-DQA2 -9407
TRAV19 -9396
CD3E -9378
TRAC -9330
CD3G -9125
HLA-DQB2 -9021
CD3D -8747
TRBC1 -8666
ZAP70 -8662
TRAV29DV5 -8326
TRAV8-4 -7607
HLA-DPB1 -7109
TRBV7-9 -6741
HLA-DRA -6613
HLA-DPA1 -5854
CD4 -4882
HLA-DQA1 -1465
HLA-DRB5 -1119
HLA-DRB1 1353
HLA-DQB1 3660
PTPN22 5604


Scavenging of heme from plasma

Scavenging of heme from plasma
1056
set Scavenging of heme from plasma
setSize 71
pANOVA 2.01e-08
s.dist -0.385
p.adjustANOVA 6.23e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
IGKV3-11 -9443
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
IGKV3-15 -7683
JCHAIN -7676
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
IGLV7-46 -6955
IGHV3-53 -6692
IGHV4-34 -6614

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IGKV3-11 -9443
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
IGKV3-15 -7683
JCHAIN -7676
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
IGLV7-46 -6955
IGHV3-53 -6692
IGHV4-34 -6614
IGHV2-5 -6583
IGHV3-48 -5881
IGLC7 -5764
IGLV3-27 -5637
IGHV3-23 -5636
IGLV8-61 -5601
IGHV1-2 -5526
IGLV1-51 -5296
IGHA1 -5247
IGKC -5232
IGHV3-7 -5228
IGLC2 -5138
IGKV3-20 -5082
IGKV1-33 -4953
IGHV4-39 -4884
IGHV3-30 -4685
IGLV1-47 -4485
IGKV1-12 -4392
IGKV2-28 -4281
IGLC1 -4280
IGHV2-70 -4223
IGHV3-11 -3626
IGHV1-46 -3558
IGLV4-69 -3305
IGLV1-40 -3024
IGKV2-30 -2958
IGKV1-17 -2929
HPX -2463
IGHV4-59 -2340
IGLV1-36 -2214
IGHA2 -2084
IGLV3-25 -1935
IGHV3-13 -1600
IGLV1-44 -1090
HBA1 -867
IGKV2D-28 -728
IGLC3 -403
IGKV3D-20 -305
IGLV10-54 -276
HBB -79
IGLV2-23 1244
APOL1 1736
IGKV5-2 3051
IGLV2-11 3601
IGKV1D-39 3771
IGLV7-43 7123
ALB 9450
IGKV1-39 9771
LRP1 11120
CD163 11297
HP 11572


Classical antibody-mediated complement activation

Classical antibody-mediated complement activation
188
set Classical antibody-mediated complement activation
setSize 69
pANOVA 2.98e-08
s.dist -0.386
p.adjustANOVA 9.02e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
IGKV3-11 -9443
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
IGKV3-15 -7683
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
IGLV7-46 -6955
IGHV3-53 -6692
IGHV4-34 -6614
IGHV2-5 -6583

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IGKV3-11 -9443
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
IGKV3-15 -7683
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
IGLV7-46 -6955
IGHV3-53 -6692
IGHV4-34 -6614
IGHV2-5 -6583
IGHV3-48 -5881
IGLC7 -5764
IGLV3-27 -5637
IGHV3-23 -5636
IGLV8-61 -5601
IGHV1-2 -5526
IGLV1-51 -5296
IGKC -5232
IGHV3-7 -5228
IGLC2 -5138
IGKV3-20 -5082
IGKV1-33 -4953
IGHV4-39 -4884
IGHV3-30 -4685
IGLV1-47 -4485
IGKV1-12 -4392
IGKV2-28 -4281
IGLC1 -4280
IGHV2-70 -4223
IGHG3 -4128
IGHV3-11 -3626
IGHV1-46 -3558
IGLV4-69 -3305
IGHG2 -3113
IGLV1-40 -3024
IGKV2-30 -2958
IGKV1-17 -2929
IGHV4-59 -2340
IGLV1-36 -2214
IGLV3-25 -1935
IGHV3-13 -1600
IGHG1 -1504
IGLV1-44 -1090
IGHG4 -760
IGKV2D-28 -728
IGLC3 -403
IGKV3D-20 -305
IGLV10-54 -276
IGLV2-23 1244
C1S 2813
IGKV5-2 3051
IGLV2-11 3601
IGKV1D-39 3771
C1R 4413
IGLV7-43 7123
IGKV1-39 9771
C1QA 11453
C1QC 11693
C1QB 11723


Cell Cycle, Mitotic

Cell Cycle, Mitotic
155
set Cell Cycle, Mitotic
setSize 501
pANOVA 4.02e-08
s.dist -0.143
p.adjustANOVA 1.19e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
CDC14A -9861
NDC1 -9817
MCM3 -9769
POLD2 -9742
RBL2 -9700
POLA1 -9660
RPA1 -9657
NUP35 -9626
AJUBA -9543
CEP76 -9542
TUBB4A -9524
CDC25B -9481
BUB3 -9475
TFDP2 -9444
NUP88 -9430
MYC -9418
CHMP7 -9399
ANAPC1 -9394
SPDL1 -9307
MCM6 -9297

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CDC14A -9861.0
NDC1 -9817.0
MCM3 -9769.0
POLD2 -9742.0
RBL2 -9700.0
POLA1 -9660.0
RPA1 -9657.0
NUP35 -9626.0
AJUBA -9543.0
CEP76 -9542.0
TUBB4A -9524.0
CDC25B -9481.0
BUB3 -9475.0
TFDP2 -9444.0
NUP88 -9430.0
MYC -9418.0
CHMP7 -9399.0
ANAPC1 -9394.0
SPDL1 -9307.0
MCM6 -9297.0
CCND2 -9246.0
CENPH -9233.0
FBXO5 -9228.0
OPTN -9165.0
HSP90AB1 -9152.0
OFD1 -9086.0
MIS12 -9038.0
CEP78 -8971.0
POLE3 -8924.0
CUL1 -8878.0
NCAPD3 -8857.0
NUP107 -8801.0
SEH1L -8792.0
AKT3 -8761.0
CEP72 -8753.0
ITGB3BP -8742.0
RPS27A -8722.0
NUP160 -8699.0
RFC3 -8694.0
LIG1 -8618.0
TP53 -8613.0
HAUS3 -8547.0
CEP57 -8544.0
CDK4 -8539.0
MAD2L1 -8491.0
DBF4 -8484.0
TUBG2 -8465.0
KIF2A -8455.0
CEP70 -8423.0
ODF2 -8342.0
CENPM -8299.0
PRIM1 -8268.0
RPS27 -8260.0
VRK1 -8230.0
RANGAP1 -8224.0
GINS4 -8200.0
ORC2 -8097.0
ORC5 -8089.0
CDC23 -8076.0
RPA3 -8069.0
DYNLL2 -8015.0
LIN9 -8001.0
PPP2R2D -7986.0
SET -7950.0
NUP43 -7792.0
RFC4 -7736.0
MCM7 -7720.0
CENPQ -7689.0
PPP2R5C -7679.0
E2F6 -7656.0
NUP155 -7633.0
MCM4 -7627.0
PSMB9 -7625.0
SFI1 -7605.0
RAN -7577.0
ORC3 -7568.0
MCM2 -7557.0
CSNK1E -7527.0
HAUS6 -7511.0
CDKN1B -7508.0
MZT2A -7471.0
NINL -7404.0
BORA -7395.0
NCAPH2 -7314.0
NUP188 -7295.0
SMC2 -7215.0
ANAPC16 -7186.0
FEN1 -7122.0
HAUS5 -7120.0
TUBA3D -7118.0
NUP205 -7051.0
PLK4 -7001.0
BTRC -6984.0
CENPJ -6905.0
MZT1 -6883.0
PCNA -6841.0
PRKAR2B -6807.0
SGO2 -6783.0
MCM10 -6777.0
RBL1 -6718.0
LPIN2 -6679.0
POLE2 -6659.0
STAG1 -6554.0
ESCO1 -6521.0
PSME1 -6399.0
NDC80 -6377.0
PSMA5 -6362.0
GORASP2 -6358.0
PPP2R5E -6283.0
H2BC9 -6264.0
RAD21 -6258.0
PCNT -6252.0
POLA2 -6222.0
CEP290 -6203.0
CENPC -6141.0
MCM8 -6138.0
ARPP19 -6085.0
POM121C -6074.0
ZWINT -6019.0
MCPH1 -5944.0
PSMC5 -5909.0
H2AZ2 -5901.0
TYMS -5813.0
BUB1B -5801.0
SKP1 -5791.0
PPP2R3B -5780.0
BUB1 -5773.0
CENPT -5770.0
SMC3 -5758.0
RRM2 -5738.0
ORC4 -5692.0
NUP133 -5674.0
PRKCA -5667.0
PRIM2 -5653.0
MNAT1 -5650.0
CDC45 -5643.0
CDK1 -5568.0
SRC -5527.0
TUBGCP6 -5515.0
RFC1 -5493.0
LIN52 -5480.0
CDC6 -5479.0
LPIN1 -5449.0
CENPL -5433.0
SMC4 -5416.0
NUP54 -5340.0
E2F5 -5304.0
LMNA -5294.0
TUBB -5289.0
AHCTF1 -5169.0
ORC1 -5158.0
NEK7 -5144.0
EMD -5130.0
EML4 -5100.0
HSP90AA1 -5083.0
ZWILCH -5036.0
CDK5RAP2 -5035.0
TUBB1 -4868.0
MYBL2 -4826.0
WEE1 -4746.0
TUBGCP5 -4715.0
CLASP2 -4711.0
RBBP4 -4658.0
CENPK -4642.0
CDK6 -4636.0
RPA2 -4620.0
PDS5A -4597.0
PSMD10 -4578.0
MZT2B -4548.0
MAX -4483.0
NUP153 -4433.0
KNTC1 -4400.0
CENPN -4391.0
NUP210 -4373.0
PSMA3 -4338.0
BANF1 -4324.0
ALMS1 -4279.0
NUF2 -4277.0
NUDC -4267.0
NCAPH -4213.0
XPO1 -4204.0
CEP131 -4139.0
TPR -4127.0
TOP2A -4125.0
LCMT1 -4047.0
CDT1 -4032.0
CC2D1B -4029.0
DNA2 -4017.0
GINS3 -3998.0
RFC5 -3986.0
AKAP9 -3928.0
ANAPC5 -3910.0
CDCA5 -3870.0
PHLDA1 -3863.0
LEMD3 -3858.0
LIN54 -3805.0
CCND1 -3717.0
CDK2 -3694.0
CKS1B -3620.0
PSME2 -3570.0
TNPO1 -3493.0
HMMR -3479.0
SKA2 -3420.0
DSN1 -3386.0
GINS2 -3279.0
LPIN3 -3221.0
NUP93 -3163.0
RANBP2 -3109.0
RCC1 -3085.0
DYRK1A -3079.0
PPP2R1B -2904.0
TUBGCP4 -2883.0
ZW10 -2813.0
CCNE1 -2791.0
CEP41 -2740.0
CENPU -2720.0
NUP42 -2718.0
CDCA8 -2626.0
CENPA -2615.0
TUBA8 -2569.0
FOXM1 -2561.0
CDC27 -2558.0
CDC25A -2547.0
CCNB1 -2524.0
TPX2 -2523.0
NCAPG -2509.0
UBB -2442.0
STAG2 -2436.0
NME7 -2347.0
CETN2 -2342.0
CEP135 -2331.0
POM121 -2295.0
CCNA1 -2231.0
PDS5B -2230.0
H2BU1 -2206.0
CEP250 -2187.0
ANAPC2 -2172.0
CENPF -2144.0
UBE2C -2114.0
ESCO2 -2104.0
PSMA2 -2032.0
PSMB1 -1960.0
CDC20 -1938.0
H2AC6 -1829.0
CCNA2 -1727.0
NUP85 -1717.0
CDC16 -1623.0
HAUS7 -1485.0
POLE -1479.0
VPS4A -1442.0
UBA52 -1437.0
NUP37 -1424.0
KIF20A -1419.0
WAPL -1381.0
PPP2R2A -1333.0
PCM1 -1329.0
NUP50 -1242.0
NEDD1 -1240.0
POLE4 -1186.0
PSME4 -1087.0
CNTRL -1047.0
DYNC1H1 -1040.0
GINS1 -976.0
GTSE1 -888.0
CABLES1 -831.0
CKAP5 -824.0
HAUS8 -804.0
SMC1A -662.0
INCENP -614.0
ESPL1 -556.0
SKP2 -520.0
CHMP2B -392.0
PKMYT1 -382.0
PSMB10 -372.0
BIRC5 -333.0
PSMA4 -118.0
NCAPG2 -117.0
USO1 -110.0
KPNB1 -109.0
E2F1 -108.0
NUMA1 -102.0
CDC26 6.0
PMF1 52.0
KIF18A 102.0
SPC24 111.0
HAUS2 112.0
CCP110 126.0
ANAPC10 141.0
NUP98 175.0
PSMD14 225.0
UBE2E1 291.0
NEK2 345.0
NUP62 395.0
BLZF1 483.0
H2BC15 524.0
UBE2I 587.0
AAAS 627.0
POLD1 646.0
AURKB 781.0
VRK2 793.0
CDC7 815.0
NEK9 870.0
ANAPC4 875.0
HAUS1 943.0
TUBG1 982.0
PSMF1 1056.0
NCAPD2 1097.0
KIF2C 1104.0
DYNC1I1 1191.0
NIPBL 1196.0
CENPI 1203.0
FBXW11 1218.0
MCM5 1277.0
CDC25C 1278.0
CEP192 1304.0
CLASP1 1310.0
PSMC4 1389.0
PSMD7 1547.0
FZR1 1793.0
CENPE 1952.0
PTTG1 2074.0
PSMC3 2182.0
KNL1 2231.0
TK1 2257.0
UBE2S 2306.0
CDK11B 2328.0
HDAC1 2347.0
PPME1 2469.0
GSK3B 2520.0
PPP2R5D 2555.0
TUBA4B 2576.0
SSNA1 2600.0
ANAPC7 2814.0
PPP1CB 2847.0
PPP1CC 2943.0
H2AZ1 2960.0
PLK1 2972.0
TUBA1C 3008.0
CENPP 3032.0
SKA1 3064.0
CDKN1A 3132.0
SPAST 3167.0
DYNLL1 3185.0
AURKA 3271.0
H2BC11 3290.0
FKBPL 3318.0
ANKLE2 3334.0
MAD1L1 3435.0
PSMA1 3451.0
PSMC6 3483.0
CEP164 3597.0
SUMO1 3612.0
SGO1 3635.0
MAPRE1 3656.0
RBX1 3691.0
CCNE2 3704.0
PSMB4 3707.0
PAFAH1B1 3738.0
PSMD13 3770.0
JAK2 3783.0
H2BC17 3795.0
PHF8 3823.0
CCNB2 3892.0
RAB8A 3907.0
TUBA4A 3909.0
ABL1 4039.0
ERCC6L 4040.0
PSMD3 4177.0
H2BC4 4239.0
PSMA6 4263.0
CSNK2A2 4323.0
TFDP1 4357.0
H2BC5 4435.0
PPP1R12A 4439.0
PSMC2 4457.0
ANAPC11 4464.0
CDKN2A 4560.0
PPP2R1A 4593.0
NDE1 4671.0
PSMB2 4680.0
CDKN2D 4820.0
RFC2 4835.0
RCC2 4844.0
UBC 4874.0
PPP2CA 4882.0
CDK7 4908.0
RAE1 5040.0
KIF23 5122.0
CDK11A 5232.0
GMNN 5280.0
LIN37 5346.0
PPP2CB 5377.0
LBR 5389.0
AKT2 5390.0
PSMB8 5433.0
E2F4 5439.0
PSMD8 5474.0
DHFR 5520.0
PSMD2 5544.0
PSMD12 5714.0
DYNC1I2 5729.0
PSMC1 5778.0
CENPO 5838.0
MASTL 5976.0
PSMD5 6029.0
H2BC12 6101.0
AKT1 6133.0
TAOK1 6148.0
H2BC21 6180.0
PSMD1 6354.0
ENSA 6452.0
CSNK2B 6563.0
CEP63 6566.0
CDKN2C 6579.0
TUBB4B 6583.0
PSME3 6605.0
H3C15 6611.5
TUBA1B 6662.0
CHMP4A 6691.0
CHMP6 6694.0
E2F3 6700.0
CHMP3 6707.0
SEC13 6793.0
PSMD11 7057.0
PPP1R12B 7089.0
PRKCB 7102.0
CCNH 7145.0
CEP152 7449.0
CSNK1D 7458.0
PPP2R5A 7512.0
FBXL18 7571.0
CNEP1R1 7586.0
H3-3A 7624.0
NUP58 7628.0
IST1 7650.0
TUBA1A 7690.0
SEM1 7739.0
CTDNEP1 7768.0
TUBGCP2 7795.0
DYNC1LI1 7881.0
DCTN3 7885.0
PSMB7 7941.0
CSNK2A1 7984.0
RAB2A 8033.0
DYNC1LI2 8092.0
GOLGA2 8366.0
MAU2 8374.0
NEK6 8427.0
ORC6 8542.0
LEMD2 8556.0
YWHAE 8584.0
NSL1 8609.0
PSMB5 8625.0
PSMA7 8719.0
SIRT2 8720.0
SDCCAG8 8730.0
TMPO 8743.0
PSMD6 8745.0
B9D2 8773.0
H2AC20 8783.0
TUBGCP3 8804.0
EP300 8816.0
PTK6 8980.0
PSMD9 9005.0
UBE2D1 9204.0
DCTN1 9214.0
CDKN2B 9248.0
PSMB6 9262.0
TUBB6 9304.0
RAB1B 9447.0
CCND3 9462.0
NDEL1 9493.0
TUBB3 9545.0
MAPK3 9636.0
RB1 9765.0
HDAC8 9800.0
YWHAG 9892.0
PSMB3 9902.0
RAB1A 9919.0
ANAPC15 9931.0
ACTR1A 10067.0
NUP214 10124.0
KMT5A 10179.0
PSMD4 10295.0
TUBB2A 10298.0
POLD4 10344.0
DCTN2 10458.0
CDKN1C 10502.0
PPP2R5B 10579.0
CHMP4B 10624.0
CHMP2A 10625.0
CLIP1 10667.0
MAPK1 10847.0
LYN 10893.0
GORASP1 10996.0
LMNB1 11079.0
E2F2 11246.0
HAUS4 11267.0
POLD3 11274.0
PRKACA 11578.0
H2AJ 11606.0


Immune System

Immune System
518
set Immune System
setSize 1892
pANOVA 4.2e-08
s.dist 0.0762
p.adjustANOVA 1.22e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
LILRB2 11743
SLC11A1 11742
P2RX1 11737
SIGLEC10 11729
OSCAR 11726
C1QB 11723
MAPKAPK3 11720
DOK3 11717
NCSTN 11715
TCIRG1 11708
AP2A1 11707
LILRA6 11705
HK3 11695
C1QC 11693
DNASE1L1 11691
SERPINA1 11685
TRIM71 11679
ANPEP 11677
LILRB4 11658
LILRB5 11651

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
LILRB2 11743.0
SLC11A1 11742.0
P2RX1 11737.0
SIGLEC10 11729.0
OSCAR 11726.0
C1QB 11723.0
MAPKAPK3 11720.0
DOK3 11717.0
NCSTN 11715.0
TCIRG1 11708.0
AP2A1 11707.0
LILRA6 11705.0
HK3 11695.0
C1QC 11693.0
DNASE1L1 11691.0
SERPINA1 11685.0
TRIM71 11679.0
ANPEP 11677.0
LILRB4 11658.0
LILRB5 11651.0
MAP3K8 11646.0
CSF2RA 11643.0
C3AR1 11629.0
RGL3 11626.0
MYD88 11614.0
LILRA5 11613.0
FGR 11610.0
LILRB1 11607.0
SIRPA 11601.0
GNS 11592.0
IL27 11586.0
ITGAX 11581.0
IFNGR2 11580.0
PRKACA 11578.0
ACAA1 11576.0
C2 11573.0
HP 11572.0
IDH1 11571.0
CLEC4G 11570.0
RASGRP4 11568.0
STXBP2 11551.0
CD63 11550.0
QSOX1 11547.0
CD300C 11546.0
FBXL19 11544.0
PVR 11541.0
RNASE2 11535.0
BCL6 11526.0
FBXO9 11524.0
HMOX1 11521.0
WASF1 11510.0
PRKCD 11506.0
FCER1G 11505.0
PTK2B 11504.0
NOD2 11501.0
ICAM5 11496.0
SIGLEC9 11493.0
TIMP1 11482.0
MOSPD2 11479.0
LAIR1 11472.0
FCGR1B 11468.0
ATP6V0A1 11467.0
IL1R2 11458.0
CD300E 11454.0
C1QA 11453.0
CTSD 11452.0
RNF135 11446.0
CTSB 11445.0
CR1 11436.0
GUSB 11435.0
S100A9 11432.0
RHOU 11427.0
SIGLEC16 11421.0
ADAM17 11419.0
HCK 11416.0
ASAH1 11411.0
NEU1 11402.0
NCKAP1L 11401.0
AGPAT2 11396.0
TREML4 11394.0
IFI30 11387.0
PTPN9 11383.0
BTK 11379.0
LTBR 11375.0
CD36 11354.0
RIPK3 11344.0
NLRC4 11341.0
TNFAIP6 11338.0
IMPDH1 11335.0
VNN1 11333.0
ALDH3B1 11330.0
FPR1 11322.0
TIMP2 11318.0
S100A8 11315.0
PECAM1 11314.0
MCEMP1 11306.0
PGAM1 11305.0
ITGAM 11288.0
BRI3 11285.0
ATP6V0D1 11283.0
NKIRAS2 11282.0
PLAC8 11276.0
UNC13D 11268.0
LILRA1 11264.0
MRAS 11257.0
FCGR1A 11256.0
PTPN6 11254.0
WAS 11238.0
GM2A 11237.0
NECTIN2 11224.0
CTSL 11213.0
ARPC1A 11206.0
PTPN18 11205.0
INPPL1 11200.0
TNFRSF1A 11197.0
CASP9 11191.0
TYK2 11189.0
NFAM1 11188.0
MYO10 11182.0
MYO9B 11181.0
CDA 11180.0
ANXA2 11174.0
IRAK3 11172.0
TRPM2 11170.0
TRAF7 11166.0
VIM 11159.0
ALOX5 11153.0
KSR1 11126.0
MEFV 11122.0
MMP2 11121.0
CYFIP1 11117.0
TNFRSF8 11115.0
C5AR1 11109.0
TNFSF13 11107.0
CD177 11101.0
IL17RA 11099.0
PYCARD 11094.0
RNF144B 11087.0
GRN 11084.0
IL1RN 11083.0
LMNB1 11079.0
S100A11 11078.0
S100A12 11077.0
RASAL2 11073.0
GLA 11064.0
LTA4H 11060.0
C4BPA 11057.0
FCGR3A 11056.0
LGALS9 11053.0
CRISPLD2 11052.0
IL10RB 11050.0
VAT1 11042.0
NCF2 11041.0
PELI3 11036.0
CFB 11024.0
TNFRSF1B 11022.0
ARRB2 11021.0
UNC93B1 11011.0
COTL1 11009.0
TLR5 10992.0
STAT6 10986.0
MARK3 10983.0
CD68 10980.0
PLEKHO2 10971.0
ITGB2 10970.0
NLRX1 10967.0
ARPC1B 10956.0
AP1B1 10946.0
RPS6KA1 10944.0
ALDOA 10937.0
SERPINB1 10935.0
GRB2 10925.0
CSTB 10924.0
ALPK1 10916.0
TOM1 10915.0
RAC1 10907.0
RAB10 10903.0
TRIM25 10901.0
LYN 10893.0
LRRC41 10885.0
PADI2 10877.0
SIGLEC7 10875.0
NCF4 10873.0
PSEN1 10871.0
ATP6V0C 10858.0
TRIM8 10856.0
MAPK1 10847.0
GLB1 10846.0
PSTPIP1 10845.0
AP1S1 10842.0
DLG4 10839.0
WSB1 10835.0
PLAUR 10834.0
SERPINB2 10828.0
TEC 10815.0
KLHL2 10814.0
CD93 10813.0
TLR8 10804.0
FPR2 10794.0
LAT2 10791.0
LILRA2 10790.0
PYGL 10789.0
MAP3K11 10785.0
ATP11A 10784.0
CTSZ 10773.0
CSF1R 10769.0
TLR2 10761.0
PTAFR 10758.0
TYROBP 10755.0
GCA 10753.0
CD55 10741.0
RGL1 10736.0
PIK3AP1 10723.0
RNF41 10711.0
PAK1 10704.0
NBEAL2 10699.0
MAP3K3 10696.0
RAPGEF3 10694.0
ARHGAP9 10674.0
CD300A 10650.0
MX2 10647.0
MMP25 10645.0
NAPRT 10642.0
SOCS3 10637.0
RHOG 10634.0
CYBA 10617.0
PILRA 10610.0
RAB24 10600.0
TSPAN14 10591.0
RGL2 10580.0
PPP2R5B 10579.0
CLU 10561.0
SIGLEC15 10557.0
C5AR2 10548.0
PKM 10547.0
LILRB3 10546.0
CD14 10542.0
EIF4G3 10534.0
PLD1 10520.0
RETN 10519.0
CTSA 10517.0
CEACAM3 10514.0
CPPED1 10512.0
ATP6V0B 10507.0
SPRED2 10481.0
JAML 10470.0
MAPK14 10466.0
IL1R1 10462.0
DCTN2 10458.0
ALAD 10444.0
ADGRG3 10443.0
AP2A2 10434.0
PTPN2 10427.0
BIN2 10421.0
ACTB 10419.0
TALDO1 10411.0
IFI27 10409.0
QPCT 10407.0
ARSB 10406.0
CLEC6A 10404.0
STK11IP 10391.0
IFNGR1 10380.0
PLCG2 10376.0
PLD2 10367.0
HAVCR2 10363.0
ARF1 10356.0
FCGR2A 10355.0
FTL 10348.0
SEC24D 10340.0
MAPK7 10339.0
MMP9 10322.0
HGF 10314.0
CSK 10310.0
PSMD4 10295.0
MAP2K6 10292.0
GYG1 10290.0
HPSE 10288.0
RNASEL 10286.0
BST1 10273.0
WASF2 10259.0
CD53 10254.0
MAP2K1 10244.0
CAPN1 10238.0
DOCK2 10229.0
GAB2 10228.0
RAB4B 10224.0
MAPK10 10215.0
GSTO1 10199.0
RAB5C 10197.0
CYBB 10196.0
GPR84 10194.0
CEBPD 10187.0
RAB3D 10172.0
RNF123 10169.0
UBAC1 10155.0
IL10 10154.0
VAV1 10149.0
AP1M1 10145.0
NUP214 10124.0
RET 10112.0
MGRN1 10105.0
CKAP4 10088.0
SYK 10086.0
RAPGEF2 10085.0
IGF2R 10077.0
TRIM41 10074.0
MGST1 10069.0
ACTR1A 10067.0
ARPC5 10048.0
CD58 10047.0
RAB31 10045.0
LRSAM1 10040.0
PPL 10037.0
PSAP 10019.0
FGFR1 10016.0
LY96 10002.0
RBCK1 9994.0
IFITM3 9970.0
GRIN2D 9962.0
LCP1 9951.0
CFP 9950.0
ICAM4 9941.0
TGFA 9932.0
FBXW2 9923.0
EIF4G1 9922.0
CSF3R 9916.0
HSPA6 9912.0
PSMB3 9902.0
DNAJC5 9897.0
GSN 9887.0
SAMHD1 9876.0
LAMTOR1 9855.0
ELMO2 9846.0
IL4R 9836.0
UBE2A 9832.0
RAF1 9820.0
CYB5R3 9808.0
VASP 9774.0
IGKV1-39 9771.0
MAP2K3 9766.0
FLT3 9764.0
APBB1IP 9763.0
MGAM 9760.0
GALNS 9756.0
PTPN1 9752.0
SLC2A3 9751.0
DNM2 9736.0
PDAP1 9730.0
GAB1 9727.0
ATP6V1D 9706.0
ATP6V1B2 9701.0
SLC15A4 9689.0
CFL1 9683.0
CLEC4D 9682.0
ADGRE5 9681.0
CARD9 9678.0
DERA 9675.0
UBA3 9647.0
ACLY 9642.0
DNAJC13 9641.0
MYO5A 9640.0
TICAM1 9637.0
MAPK3 9636.0
IFITM2 9612.0
ARSA 9608.0
VAMP7 9561.0
DBNL 9555.0
MICB 9553.0
GMFG 9547.0
PGM2 9542.0
SDCBP 9536.0
LRG1 9534.0
CTSC 9524.0
UBE2R2 9521.0
UBA1 9518.0
AP2S1 9504.0
AREL1 9496.0
CCR2 9487.0
ARPC3 9484.0
EBI3 9483.0
CYSTM1 9471.0
DCTN4 9451.0
S100P 9448.0
P4HB 9433.0
PTPRJ 9428.0
CAT 9425.0
AMPD3 9412.0
KIR2DL3 9401.0
CRK 9373.0
TLR4 9355.0
CLTC 9346.0
CD33 9340.0
SIGLEC12 9334.0
MNDA 9331.0
ASB1 9329.0
NEDD4L 9328.0
DCTN6 9325.0
FOLR3 9323.0
IRS2 9312.0
LAMTOR2 9311.0
TNFSF12 9307.0
RAB7A 9295.0
LGALS3 9294.0
HECTD3 9275.0
PRKCE 9268.0
PSMB6 9262.0
LIMK1 9261.0
TMBIM1 9252.0
KIR2DL4 9236.0
ARL8A 9235.0
TRIM34 9231.0
ARPC4 9223.0
DCTN1 9214.0
ARPC2 9212.0
LONRF1 9210.0
SERPINB6 9209.0
UBE2D1 9204.0
FCN1 9194.0
VPS35L 9180.0
STX3 9174.0
FBXL5 9166.0
MVP 9155.0
P2RX7 9153.0
FBXO6 9143.0
ADAM10 9130.0
STAT5A 9106.0
DTX4 9053.0
DUSP3 9049.0
SP100 9018.0
ARG1 9013.0
FCAR 9011.0
PSMD9 9005.0
COMMD9 9004.0
KL 9001.0
IQGAP1 8998.0
RNF130 8992.0
MSN 8930.0
SOS2 8927.0
TLN1 8909.0
IKBKG 8902.0
IQGAP2 8896.0
NLRP3 8894.0
TRAPPC1 8880.0
HECW2 8864.0
RASGRF1 8849.0
SELL 8826.0
EP300 8816.0
ATP6V1C1 8809.0
RNASET2 8806.0
STIM1 8775.0
CBL 8765.0
RHOA 8752.0
TLR1 8749.0
MEF2A 8747.0
PSMD6 8745.0
JAK3 8721.0
PSMA7 8719.0
FRS3 8680.0
TREML2 8674.0
TXN 8653.0
MAOA 8643.0
SPRED1 8630.0
IKBKE 8629.0
IRF7 8626.0
PSMB5 8625.0
TANK 8608.0
LAMP1 8606.0
PNP 8604.0
CAPZB 8593.0
SNAP29 8589.0
SOD2 8563.0
PITPNA 8561.0
ACTG1 8547.0
DOCK1 8538.0
ATP6V1A 8486.0
CD44 8470.0
FBXO40 8461.0
NEDD4 8443.0
CAP1 8422.0
IFNAR2 8363.0
CCR1 8334.0
FKBP1A 8329.0
UBE3B 8317.0
ATP6V0E1 8302.0
OASL 8297.0
DNAJC3 8291.0
STAT3 8289.0
REL 8271.0
GAA 8265.0
PDGFRA 8251.0
TRIP12 8230.0
BTNL8 8212.0
PGLYRP2 8211.0
RILP 8209.0
CD1D 8207.0
CLEC4E 8196.0
IL17C 8186.0
STX4 8182.0
LRRFIP1 8161.0
EIF4E3 8149.0
VAPA 8135.0
CTNNB1 8119.0
ITGAV 8115.0
CNPY3 8102.0
DYNC1LI2 8092.0
IFNAR1 8080.0
IFI35 8075.0
RNF7 8055.0
CD300LF 8051.0
MANBA 8050.0
TRIM21 8042.0
CAPZA1 8032.0
IRF8 8023.0
MUC1 8020.0
VAMP3 8012.0
CAPZA2 7999.0
INPP5D 7960.0
KLC1 7957.0
PSMB7 7941.0
SHC1 7938.0
RAB27A 7933.0
CLEC4A 7903.0
DCTN3 7885.0
DYNC1LI1 7881.0
NCKAP1 7871.0
CREG1 7822.0
ASB4 7815.0
RNF182 7810.0
TOLLIP 7802.0
SEM1 7739.0
TREM1 7737.0
AGER 7730.0
MUC6 7695.0
CLTA 7680.0
NOS1 7676.0
CANT1 7672.0
ELOC 7671.0
CDC34 7669.0
HIF1A 7668.0
CMTM6 7664.0
ABI1 7663.0
PDXK 7660.0
IRF2 7653.0
IST1 7650.0
IRAK1 7649.0
TLR6 7631.0
NUP58 7628.0
IL19 7614.0
UBE2J2 7605.0
ATP6V1E1 7588.0
NPEPPS 7587.0
CUL7 7584.0
RAB6A 7579.0
PRCP 7572.0
FBXL18 7571.0
FBXL13 7563.0
NPC2 7560.0
PTPRC 7546.0
WDR83 7538.0
UBE2F 7529.0
PPP2R5A 7512.0
ELOB 7511.0
CD46 7504.0
UBE2J1 7495.0
CTSK 7494.0
DYNLT1 7489.0
NCF1 7481.0
VAV2 7476.0
DDOST 7465.0
NFKBIB 7438.0
POU2F1 7429.0
TRIM6 7415.0
METTL7A 7399.0
PANX1 7397.0
KCNAB2 7393.0
LAMP2 7357.0
ACTR2 7352.0
CDC42 7337.0
AP2M1 7323.0
PTEN 7321.0
PTPN23 7305.0
STK10 7292.0
TNFSF13B 7272.0
IL27RA 7256.0
IRF5 7255.0
MAPK13 7251.0
CSF2RB 7244.0
CTSS 7190.0
CHUK 7179.0
TNFSF9 7175.0
IGLV7-43 7123.0
TRIM38 7120.0
MUC16 7106.0
PRKCB 7102.0
SEC24C 7065.0
PSMD11 7057.0
NHLRC3 7045.0
SIRPB1 7036.0
RELB 7028.0
RAP1A 7021.0
ROCK1 7020.0
TRIM9 7001.0
IL18 6992.0
ENAH 6964.0
SEC24A 6928.0
HEXB 6925.0
SIPA1 6881.0
TNIP2 6869.0
TIRAP 6862.0
EIF4E2 6838.0
SEC13 6793.0
UBR2 6786.0
NDUFC2 6785.0
FOXO3 6773.0
CTSH 6758.0
RASA1 6726.0
MAN2B1 6709.0
HSPA1A 6708.0
WIPF2 6706.0
ITLN1 6703.0
MUC5B 6697.0
FLNB 6668.0
MRC1 6666.0
SOCS1 6664.0
ACTR3 6644.0
VRK3 6628.0
H3C15 6611.5
PSME3 6605.0
OSTF1 6599.0
ATOX1 6597.0
TUBB4B 6583.0
CSNK2B 6563.0
YPEL5 6553.0
PIGR 6544.0
FBXL20 6542.0
FUCA2 6509.0
PIK3CD 6507.0
FUCA1 6504.0
MAPKAPK2 6495.0
NFASC 6488.0
FABP5 6480.0
SPSB2 6459.0
PLD3 6403.0
UBE2D3 6400.0
SIGLEC11 6390.0
FTH1 6366.0
KIF5B 6360.0
PSMD1 6354.0
ERAP2 6340.0
HNRNPA2B1 6339.0
MYH9 6290.0
PIK3R2 6269.0
TNFRSF12A 6255.0
SIGLEC5 6250.0
CASP1 6238.0
KCTD6 6231.0
COPB1 6181.0
ERBB3 6166.0
ASB14 6139.0
PJA2 6137.0
ITPR2 6136.0
AKT1 6133.0
CLEC7A 6117.0
PIK3CB 6109.0
ATG7 6077.0
CASP4 6041.0
PSMD5 6029.0
APAF1 6024.0
CXCR1 6006.0
ADAM8 5994.0
ORAI2 5982.0
PRDX4 5952.0
MAVS 5950.0
KEAP1 5943.0
EIF4A1 5928.0
CAB39 5909.0
ZDHHC9 5887.0
SMARCA4 5879.0
ARRB1 5865.0
FLNA 5854.0
DNM1 5834.0
PAK2 5789.0
GLIPR1 5779.0
PSMC1 5778.0
RNF19B 5769.0
PDPK1 5768.0
CLEC5A 5765.0
IL15RA 5741.0
POLR2F 5738.0
DYNC1I2 5729.0
FADD 5721.0
ARAF 5720.0
PSMD12 5714.0
PRKCSH 5698.0
UBOX5 5691.0
RNASE6 5684.0
HEBP2 5680.0
VAV3 5645.0
FBXO41 5643.0
PTPN22 5604.0
CREBBP 5593.0
PDE6D 5582.0
TICAM2 5572.0
NF1 5568.0
RACGAP1 5554.0
PSMD2 5544.0
TBK1 5538.0
UBE2L3 5518.0
IL1RAP 5514.0
C4B 5483.0
PSMD8 5474.0
SPTBN5 5455.0
DGAT1 5440.0
PSMB8 5433.0
TKFC 5424.0
TRIM26 5402.0
CD300LD 5392.0
AKT2 5390.0
PPP2CB 5377.0
RAP1B 5363.0
RNF217 5321.0
OPRD1 5286.0
ICAM3 5285.0
GDI2 5257.0
POLR2E 5238.0
LPCAT1 5222.0
IKBKB 5156.0
ATP6V1F 5145.0
UBE4A 5137.0
SURF4 5135.0
KIF23 5122.0
CNN2 5113.0
GBP6 5111.0
B4GALT1 5109.0
TAB3 5102.0
RAC2 5082.0
MAP2K2 5079.0
ASB6 5074.0
SPRED3 5073.0
RAP2C 5053.0
ATP6V1H 5047.0
RAE1 5040.0
FBXO11 5018.0
SRP14 5005.0
BOLA2 4983.0
DUSP1 4970.0
CALR 4966.0
RAB5B 4935.0
ZBTB16 4930.0
ICAM1 4889.0
PPP2CA 4882.0
UBC 4874.0
CD99 4846.0
UBE2H 4795.0
C5 4786.0
PGM1 4743.0
CNTF 4687.0
PSMB2 4680.0
GPI 4667.0
TRIM5 4662.0
TARM1 4634.0
ATP11B 4630.0
PPP2R1A 4593.0
MAP3K1 4584.0
MAP2K4 4579.0
PIAS1 4569.0
ORM2 4551.0
SAR1B 4545.0
TMEM30A 4528.0
SEC61B 4523.0
ANAPC11 4464.0
STAT5B 4460.0
PSMC2 4457.0
APEH 4454.0
CGAS 4448.0
HSPA1B 4429.0
C1R 4413.0
SEC24B 4410.0
KIF3B 4392.0
OTUD5 4370.0
RAB18 4366.0
SNAP23 4343.0
CASP10 4326.0
CEACAM1 4318.0
OAS1 4294.0
KIF3C 4286.0
GSDMD 4284.0
VCP 4271.0
PSMA6 4263.0
VAMP8 4250.0
FRK 4243.0
ACTR10 4228.0
PTPN12 4198.0
PSMD3 4177.0
VEGFA 4174.0
PDCD1LG2 4134.0
FAF2 4132.0
STAT2 4121.0
AHCYL1 4099.0
BCL10 4090.0
RNF114 4069.0
KCMF1 4047.0
ABL1 4039.0
ATF1 4020.0
IL33 4019.0
CASP3 4013.0
TAPBP 4012.0
SEC61A1 3976.0
PDZD11 3960.0
CD300LB 3957.0
NFKBIA 3946.0
UBE2M 3919.0
DUSP5 3898.0
SERPINB10 3849.0
RAPGEF1 3848.0
FBXW5 3834.0
AP1G1 3828.0
TRIM3 3808.0
LY86 3800.0
PPM1B 3791.0
JAK2 3783.0
HVCN1 3781.0
IGKV1D-39 3771.0
PSMD13 3770.0
LEAP2 3767.0
TRIM17 3722.0
PSMB4 3707.0
RBX1 3691.0
BTN2A1 3689.0
BATF 3664.0
HLA-DQB1 3660.0
SUMO1 3612.0
IGLV2-11 3601.0
DLG2 3575.0
CST3 3572.0
ADAR 3524.0
UBA6 3493.0
PSMC6 3483.0
ORM1 3469.0
ANXA1 3452.0
PSMA1 3451.0
POLR2L 3450.0
SPTB 3448.0
STOM 3437.0
FBXL15 3433.0
TAX1BP1 3407.0
UBE2W 3340.0
LYPLA1 3333.0
APP 3315.0
PIM1 3292.0
PELI2 3259.0
VTN 3250.0
KLC3 3246.0
IL6R 3203.0
DYNLL1 3185.0
GHDC 3169.0
HERC4 3151.0
HERC3 3144.0
CDKN1A 3132.0
SMURF1 3123.0
HLA-C 3114.0
KRAS 3113.0
IL17RB 3105.0
CLEC4C 3103.0
SLCO4C1 3100.0
ECSIT 3063.0
IGKV5-2 3051.0
MCL1 2999.0
TNFSF14 2998.0
UBE2Q1 2996.0
ERP44 2957.0
PPP1CC 2943.0
RAB14 2942.0
NLRC5 2931.0
IL15 2899.0
ITGAL 2879.0
PDIA3 2874.0
PTPN11 2859.0
PPP1CB 2847.0
UBR4 2841.0
CXCL2 2835.0
RLIM 2826.0
ANAPC7 2814.0
C1S 2813.0
PIK3R3 2799.0
LAMA5 2789.0
UBE2K 2757.0
PDGFRB 2740.0
MAP3K7 2721.0
BRAP 2707.0
GGH 2692.0
CRCP 2663.0
FBXO15 2646.0
FBXL4 2633.0
COL1A2 2609.0
DDX41 2607.0
DSP 2606.0
CLEC12A 2566.0
ASB8 2565.0
FCER2 2563.0
PPP2R5D 2555.0
SPSB1 2539.0
PML 2526.0
NANOG 2509.0
HSPA5 2508.0
IFI6 2505.0
HECTD2 2501.0
ATP7A 2494.0
MKRN1 2474.0
EPPIN 2443.0
CD86 2386.0
OSMR 2372.0
PLAU 2369.0
PPP3CB 2367.0
DIAPH1 2357.0
PAFAH1B2 2356.0
HTN1 2343.0
TRIM14 2339.0
SHOC2 2336.0
MAPKAP1 2319.0
HLA-B 2308.0
UBE2S 2306.0
KBTBD7 2300.0
FBXO27 2289.0
CPN2 2284.0
IRF9 2281.0
CFD 2249.0
MADCAM1 2244.0
IFI16 2208.0
IL18R1 2191.0
PSMC3 2182.0
SEC22B 2167.0
TXLNA 2160.0
TAB1 2158.0
UNKL 2140.0
CTF1 2122.0
EIF4E 2104.0
LAMTOR3 2053.0
TNFRSF14 2048.0
TRIM36 2044.0
YWHAB 2038.0
LPO 2037.0
SEC31A 2016.0
PGLYRP1 1994.0
CENPE 1952.0
IP6K2 1934.0
ITGA2B 1927.0
ATP6AP2 1907.0
C3 1898.0
ITCH 1890.0
PELI1 1876.0
AIM2 1862.0
POLR3K 1842.0
SEC23A 1838.0
NRAS 1826.0
FZR1 1793.0
C4A 1786.0
AP1S3 1783.0
GSTP1 1776.0
MAPK12 1731.0
COMMD3 1730.0
IL18RAP 1682.0
CUL3 1679.0
SH3KBP1 1675.0
SIAH1 1614.0
ATP8B4 1600.0
RNF111 1594.0
SPTA1 1589.0
IL10RA 1577.0
PSMD7 1547.0
TREX1 1531.0
UBE2G1 1526.0
PDGFA 1502.0
UBA7 1496.0
CXCR2 1488.0
FGF23 1439.0
EIF4G2 1421.0
RANBP9 1414.0
JUNB 1397.0
FCGR2B 1390.0
PSMC4 1389.0
A1BG 1362.0
HLA-DRB1 1353.0
NF2 1346.0
HCST 1343.0
DTX3L 1336.0
NFKB2 1272.0
RASAL1 1266.0
CLCF1 1263.0
IGLV2-23 1244.0
OPRM1 1233.0
RAB3A 1226.0
FBXW11 1218.0
VCL 1210.0
RCE1 1209.0
CAMK2G 1201.0
DYNC1I1 1191.0
POLR3C 1189.0
PFKL 1186.0
FBXO22 1174.0
MTOR 1162.0
IL31RA 1134.0
SIAH2 1121.0
KIF2C 1104.0
MAP2K7 1099.0
TRIM22 1069.0
PSMF1 1056.0
RNASE3 1013.0
DUSP10 1006.0
RAP2B 1004.0
TMEM179B 986.0
POLR1D 983.0
BST2 980.0
PRKG1 933.0
AREG 932.0
TNFRSF11A 930.0
GAN 926.0
TREML1 901.0
S100A1 892.0
ANAPC4 875.0
C6orf120 822.0
IL18BP 817.0
POLR3A 782.0
PTPN14 770.0
RIPK2 769.0
CISH 756.0
PLPP5 750.0
RNF14 749.0
UBE2E3 718.0
NOD1 699.0
TNFRSF9 698.0
STX1A 642.0
AAAS 627.0
VHL 591.0
PTPN3 566.0
SPTBN2 565.0
RIPK1 553.0
CD101 551.0
KIR3DL1 521.0
ULBP3 517.0
LCP2 514.0
FBXL12 489.0
CA1 470.0
CD200 463.0
HECTD1 462.0
DAPP1 450.0
CUL2 443.0
RNF25 430.0
EIF2AK2 426.0
BRAF 421.0
EREG 410.0
OSM 405.0
NUP62 395.0
CD40 394.0
MMP8 336.0
PAG1 322.0
PPP3R1 308.0
C8G 292.0
UBE2E1 291.0
EGF 238.0
MLST8 236.0
PSMD14 225.0
PIN1 202.0
CRLF1 192.0
ARMC8 184.0
NUP98 175.0
UBE3C 142.0
ANAPC10 141.0
SIGLEC14 129.0
MT2A 107.0
KIF18A 102.0
MAGT1 71.0
PTPN20 60.0
CXCL1 35.0
SLC44A2 34.0
CDK13 32.0
UBE2B 30.0
SH3RF1 26.0
CDC26 6.0
OLFM4 -31.0
RCHY1 -45.0
ANO6 -52.0
PEA15 -54.0
AIP -76.0
HBB -79.0
KPNB1 -109.0
PSMA4 -118.0
PSPN -145.0
FBXO7 -211.0
CPNE3 -215.0
SUGT1 -227.0
CRKL -238.0
DNM3 -250.0
CCT8 -260.0
MAPK11 -273.0
IGLV10-54 -276.0
ASB16 -292.0
RAP1GAP -297.0
BCL2L1 -300.0
ARL2 -303.0
IGKV3D-20 -305.0
MASP2 -330.0
BIRC5 -333.0
FNTB -357.0
PSMB10 -372.0
VWF -373.0
DEGS1 -381.0
MUC12 -387.0
HBEGF -398.0
NME2 -399.0
IGLC3 -403.0
PPP3CA -429.0
STBD1 -458.0
STING1 -472.0
KLHL42 -504.0
SKP2 -520.0
PAK3 -533.0
TRIM11 -569.0
CTSV -594.0
TGFB1 -615.0
YWHAZ -647.0
POMC -667.0
NRG4 -681.0
KPNA4 -701.0
IGKV2D-28 -728.0
FBXO17 -729.0
BTNL9 -733.0
LRRC7 -743.0
FBXW9 -745.0
MICA -759.0
IGHG4 -760.0
LYZ -787.0
CD70 -822.0
PRDX6 -823.0
ICMT -830.0
PTPRA -863.0
DCTN5 -898.0
EIF4A3 -915.0
NDN -925.0
KLHL21 -932.0
TNFSF4 -940.0
PROS1 -948.0
SLPI -957.0
FBXL8 -998.0
PTX3 -1006.0
IL13RA1 -1012.0
KSR2 -1021.0
DYNC1H1 -1040.0
MUCL1 -1043.0
EEA1 -1079.0
PSME4 -1087.0
IGLV1-44 -1090.0
TAP2 -1094.0
TNFRSF13C -1102.0
UBR1 -1115.0
HLA-DRB5 -1119.0
TRIM10 -1129.0
FSCN1 -1130.0
PIK3CA -1131.0
CPNE1 -1135.0
GFRA2 -1149.0
ADGRE3 -1159.0
RASGEF1A -1177.0
KLC4 -1189.0
BAIAP2 -1231.0
NUP50 -1242.0
HNRNPF -1277.0
CANX -1278.0
IL17RC -1293.0
HLA-H -1311.0
DEFA1 -1338.0
TRAF6 -1353.0
CRACR2A -1363.0
TRIB3 -1365.0
WASL -1370.0
TNFAIP3 -1377.0
FBXO30 -1391.0
KIR2DL1 -1395.0
CLEC10A -1396.0
ELMO1 -1412.0
KIF20A -1419.0
NUP37 -1424.0
UBA52 -1437.0
JUN -1440.0
HLA-DQA1 -1465.0
IGHG1 -1504.0
LAIR2 -1555.0
TRIM62 -1567.0
NPDC1 -1573.0
C4BPB -1592.0
IGHV3-13 -1600.0
CDC16 -1623.0
DDX3X -1650.0
HUWE1 -1658.0
PPP5C -1699.0
DEFA3 -1715.0
NUP85 -1717.0
RPS6KA2 -1720.0
MME -1743.0
FN1 -1748.0
BIRC2 -1798.0
KBTBD8 -1854.0
NLRP1 -1858.0
ASB13 -1888.0
PTPRB -1899.0
EPX -1916.0
RNF115 -1917.0
F13A1 -1925.0
KIF4A -1930.0
IGLV3-25 -1935.0
CDC20 -1938.0
PSMB1 -1960.0
FBXW7 -1985.0
BRK1 -2011.0
PSMA2 -2032.0
TLR9 -2033.0
FGF22 -2040.0
OSBPL1A -2043.0
HACE1 -2045.0
JUP -2056.0
ATP6V1C2 -2065.0
POLR3GL -2090.0
UBE2C -2114.0
GHR -2157.0
SYNGR1 -2163.0
NFKB1 -2166.0
PCBP2 -2170.0
ANAPC2 -2172.0
IGLV1-36 -2214.0
HLA-F -2235.0
CNKSR2 -2256.0
ZNRF1 -2283.0
POM121 -2295.0
ASB3 -2302.0
LAG3 -2316.0
SEC61G -2328.0
IGHV4-59 -2340.0
PAQR3 -2356.0
PI3 -2357.0
STUB1 -2360.0
AGL -2364.0
PTPRN2 -2372.0
UBE2V2 -2394.0
CXCL8 -2431.0
NFKBIE -2432.0
UBB -2442.0
MMP1 -2443.0
RNF6 -2457.0
HLA-E -2458.0
KIF26A -2475.0
ARIH1 -2476.0
XRCC5 -2484.0
CUL5 -2538.0
CDC27 -2558.0
RELA -2563.0
MRC2 -2568.0
UBE2E2 -2589.0
GBP2 -2594.0
FCGR3B -2630.0
DUSP4 -2651.0
CHIT1 -2666.0
EPGN -2690.0
NUP42 -2718.0
ERAP1 -2722.0
CDH1 -2771.0
UBE2D2 -2828.0
TRIM56 -2840.0
HERC1 -2856.0
ITGB3 -2871.0
IL1RL1 -2872.0
MYO1C -2881.0
RNF34 -2887.0
PPP2R1B -2904.0
SIGLEC1 -2907.0
IL6ST -2926.0
IGKV1-17 -2929.0
CIITA -2953.0
IGKV2-30 -2958.0
LILRA4 -3023.0
IGLV1-40 -3024.0
XAF1 -3033.0
PYGB -3068.0
SH2B1 -3096.0
CASP2 -3098.0
SQSTM1 -3105.0
RANBP2 -3109.0
IGHG2 -3113.0
HRAS -3116.0
SOCS2 -3131.0
SLC2A5 -3147.0
HLA-DMA -3148.0
IRF3 -3150.0
UBE2N -3154.0
NUP93 -3163.0
DUSP6 -3175.0
DUSP7 -3183.0
CD59 -3215.0
ASB7 -3224.0
DEFA4 -3234.0
HLA-G -3238.0
PDE12 -3246.0
KIF15 -3250.0
DHX58 -3255.0
SEC61A2 -3262.0
SOS1 -3263.0
KBTBD6 -3285.0
PIK3C3 -3291.0
RNF213 -3297.0
KLC2 -3299.0
IGLV4-69 -3305.0
AAMP -3318.0
PTGES2 -3328.0
PTK2 -3332.0
KLHL11 -3335.0
EDA2R -3372.0
FNTA -3378.0
DSN1 -3386.0
UBE2V1 -3427.0
TIFA -3429.0
RPS6KA3 -3451.0
PILRB -3453.0
THOP1 -3487.0
UBE2O -3495.0
HRNR -3513.0
MIB2 -3519.0
KLHL9 -3528.0
TAB2 -3529.0
WIPF1 -3530.0
IGHV1-46 -3558.0
PSME2 -3570.0
HGSNAT -3596.0
PTPN7 -3608.0
POLR2H -3611.0
FBXO44 -3624.0
IGHV3-11 -3626.0
MLEC -3628.0
S100B -3661.0
AOC1 -3663.0
AP2B1 -3690.0
ITGB5 -3701.0
HLA-DOB -3713.0
CCND1 -3717.0
FGFR2 -3732.0
CREB1 -3751.0
UFL1 -3754.0
LNPEP -3755.0
PGRMC1 -3760.0
CD209 -3788.0
SOCS5 -3789.0
MEF2C -3791.0
ITPR1 -3809.0
FOS -3812.0
BLMH -3814.0
RNF220 -3818.0
KPNA2 -3851.0
IL4 -3901.0
POLR2K -3902.0
ANAPC5 -3910.0
TRIM69 -3915.0
CD19 -3919.0
UBE3A -3930.0
FBXW12 -3961.0
DHX36 -3988.0
FGL2 -4013.0
IL7 -4028.0
LTN1 -4050.0
KIF11 -4054.0
ILF2 -4055.0
IL12RB1 -4073.0
ANGPT1 -4083.0
TPR -4127.0
IGHG3 -4128.0
NCR3 -4141.0
DPP7 -4153.0
FRS2 -4166.0
IFITM1 -4191.0
KIR2DS4 -4195.0
TXNDC5 -4205.0
IGHV2-70 -4223.0
RASA2 -4255.0
BTN1A1 -4262.0
KPNA3 -4263.0
RBBP6 -4274.0
KPNA1 -4278.0
IGLC1 -4280.0
IGKV2-28 -4281.0
FBXO10 -4325.0
PSMA3 -4338.0
RSAD2 -4369.0
CD1A -4372.0
NUP210 -4373.0
IGKV1-12 -4392.0
UBA5 -4394.0
PIK3R4 -4411.0
NUP153 -4433.0
TLR7 -4434.0
ATP6V1G1 -4463.0
KIR3DL2 -4472.0
IGLV1-47 -4485.0
ABHD17C -4491.0
HSP90B1 -4493.0
TXNIP -4515.0
RNF4 -4522.0
NFATC1 -4523.0
RBSN -4545.0
PPIA -4561.0
PSMD10 -4578.0
CCNF -4581.0
ANAPC13 -4582.0
SHC2 -4611.0
BTBD1 -4647.0
RAB9B -4668.0
TRIM37 -4672.0
RASGRP2 -4683.0
IGHV3-30 -4685.0
TMC6 -4698.0
TNFSF15 -4730.0
TNF -4731.0
HERC2 -4759.0
GOLGA7 -4761.0
CYFIP2 -4772.0
CD180 -4809.0
ITGB1 -4850.0
CD81 -4851.0
SNRPA1 -4867.0
SIKE1 -4878.0
BTLA -4879.0
CD4 -4882.0
IGHV4-39 -4884.0
LCN2 -4914.0
KLRC2 -4927.0
ATP6V0A2 -4935.0
ATF2 -4941.0
FBXL3 -4948.0
IGKV1-33 -4953.0
MRE11 -4960.0
POLR3B -4975.0
SIGLEC8 -5019.0
CSF1 -5020.0
ACTR1B -5027.0
PPIE -5064.0
IGKV3-20 -5082.0
HSP90AA1 -5083.0
CEACAM6 -5119.0
ICOSLG -5124.0
IGLC2 -5138.0
IGHM -5149.0
CALM1 -5150.0
TRAF3 -5198.0
TRIM39 -5206.0
CASP8 -5208.0
ENPP4 -5217.0
PLA2G6 -5218.0
IGHD -5224.0
IGHV3-7 -5228.0
IGKC -5232.0
PRKDC -5261.0
KIFAP3 -5269.0
IL16 -5282.0
TCP1 -5286.0
TUBB -5289.0
IGLV1-51 -5296.0
ATG5 -5297.0
DET1 -5321.0
RNF19A -5325.0
PRLR -5338.0
MX1 -5339.0
NUP54 -5340.0
FBXO2 -5352.0
COLEC12 -5383.0
ZNRF2 -5396.0
HLA-A -5456.0
ASB9 -5468.0
CRISP3 -5472.0
DUSP8 -5474.0
BTN2A2 -5521.0
IGHV1-2 -5526.0
SRC -5527.0
FGFR4 -5531.0
PA2G4 -5544.0
TAP1 -5549.0
CHI3L1 -5551.0
DHX9 -5556.0
ATG12 -5591.0
CD8B -5592.0
IGLV8-61 -5601.0
IL20RB -5608.0
SIGIRR -5612.0
IGHV3-23 -5636.0
IGLV3-27 -5637.0
YES1 -5662.0
NUP133 -5674.0
CTSG -5681.0
ASB2 -5702.0
PPBP -5719.0
ITPR3 -5727.0
IGLC7 -5764.0
IRF1 -5779.0
KLHL20 -5781.0
SKP1 -5791.0
IFIH1 -5792.0
USP18 -5796.0
CCR5 -5824.0
HLA-DMB -5833.0
RAB44 -5839.0
ATP6V1E2 -5845.0
HLA-DPA1 -5854.0
SOD1 -5860.0
PTPN13 -5867.0
IGHV3-48 -5881.0
RICTOR -5883.0
PSMC5 -5909.0
LRR1 -5916.0
MAPK9 -5918.0
BTN3A1 -5922.0
CR2 -5934.0
AGA -5943.0
CD74 -5947.0
IFNG -5957.0
RASGRP3 -5976.0
MS4A3 -5983.0
FBXW8 -5993.0
FBXL22 -6026.0
ELANE -6034.0
UBE2Z -6061.0
ABCA13 -6063.0
FBXL14 -6067.0
POM121C -6074.0
ALDOC -6087.0
OLR1 -6122.0
CLEC2B -6125.0
IGHE -6130.0
RNF126 -6188.0
ATAD3B -6192.0
CEP290 -6203.0
IL17RE -6208.0
SLAMF7 -6215.0
TCN1 -6219.0
GRAP2 -6236.0
IL1B -6271.0
IL12A -6273.0
TNFSF11 -6280.0
ABHD17A -6281.0
PPP2R5E -6283.0
IFIT3 -6286.0
RAB37 -6287.0
ZBP1 -6305.0
CCL4 -6310.0
APRT -6333.0
PSMA5 -6362.0
PRTN3 -6370.0
PSME1 -6399.0
UBE2D4 -6409.0
BRWD1 -6422.0
POLR3F -6436.0
CTLA4 -6445.0
MTAP -6466.0
KLHL13 -6472.0
WASF3 -6482.0
CEACAM8 -6488.0
CNKSR1 -6492.0
BLNK -6523.0
LTF -6540.0
ISG20 -6579.0
IGHV2-5 -6583.0
KLHL5 -6587.0
IL3RA -6591.0
HLA-DRA -6613.0
IGHV4-34 -6614.0
FYN -6619.0
DLG1 -6621.0
MUC20 -6632.0
ABHD17B -6671.0
IRAK2 -6676.0
IGHV3-53 -6692.0
SMAD3 -6699.0
CD22 -6705.0
IRS1 -6714.0
TRAF2 -6717.0
UBE2L6 -6722.0
UBE3D -6740.0
TRBV7-9 -6741.0
FBXO21 -6775.0
IFNLR1 -6776.0
TLR10 -6794.0
IL2RA -6803.0
ISG15 -6814.0
MIF -6822.0
NOS3 -6838.0
GBP3 -6848.0
EGR1 -6878.0
GBP1 -6908.0
IL21R -6918.0
RASA4 -6928.0
BCL2 -6938.0
RASAL3 -6941.0
KLRG1 -6948.0
IGLV7-46 -6955.0
ELK1 -6971.0
DUSP2 -6972.0
SYNGAP1 -6982.0
BTRC -6984.0
NCKIPSD -6991.0
POLR3E -6993.0
IL11RA -7002.0
IRF4 -7023.0
FRMPD3 -7031.0
SERPING1 -7047.0
NUP205 -7051.0
PHB -7069.0
EEF2 -7073.0
CD79B -7082.0
TRIM46 -7104.0
HLA-DPB1 -7109.0
BPI -7115.0
IRF6 -7132.0
FBXW4 -7135.0
ORAI1 -7149.0
RALGDS -7168.0
MAP3K14 -7171.0
CXCL10 -7177.0
OAS2 -7204.0
CAND1 -7207.0
AZU1 -7221.0
RPS6KA5 -7223.0
TRAIP -7227.0
OAS3 -7230.0
VAMP2 -7244.0
SHC3 -7255.0
KIF5A -7265.0
TBC1D10C -7271.0
SLC27A2 -7272.0
CTSO -7276.0
RNF216 -7294.0
NUP188 -7295.0
IGKV4-1 -7302.0
KRT1 -7308.0
B2M -7346.0
IGLV3-19 -7358.0
TRIM45 -7361.0
TMEM63A -7364.0
IGKV1-5 -7365.0
SVIP -7384.0
FGF2 -7401.0
AP1M2 -7416.0
CD274 -7428.0
ARIH2 -7444.0
IGLV2-8 -7468.0
CD8A -7501.0
MUC4 -7504.0
MYLIP -7517.0
NCAM1 -7535.0
IGLV3-12 -7540.0
PRKG2 -7544.0
KPNA5 -7556.0
SARM1 -7566.0
IGHV1-69 -7589.0
BTN3A3 -7596.0
TRAV8-4 -7607.0
BTBD6 -7613.0
PSMB9 -7625.0
NIT2 -7632.0
NUP155 -7633.0
CAMP -7637.0
KLRK1 -7644.0
SCAMP1 -7668.0
PPP2R5C -7679.0
IGKV3-15 -7683.0
HMGB1 -7684.0
TRIM68 -7697.0
KLRD1 -7719.0
CD226 -7762.0
XRCC6 -7770.0
NUP43 -7792.0
POLR1C -7797.0
ABI2 -7811.0
NKIRAS1 -7813.0
TRIM4 -7821.0
S1PR1 -7833.0
HNRNPDL -7836.0
ITGB7 -7855.0
POLR3G -7858.0
PIANP -7863.0
CCL5 -7923.0
GZMM -7924.0
HERC5 -7927.0
TPP2 -7940.0
AP1S2 -7941.0
RALA -7942.0
KLHL22 -7945.0
MPO -7958.0
ITGA4 -7966.0
PDCD1 -7990.0
BLK -7991.0
TRPC1 -7994.0
TNFRSF17 -7998.0
DYNLL2 -8015.0
EDARADD -8023.0
ATP6V1G2 -8049.0
MS4A2 -8050.0
UBE2G2 -8057.0
CD80 -8067.0
CDC23 -8076.0
FGF7 -8090.0
JAK1 -8098.0
NCR3LG1 -8113.0
MAPK8 -8128.0
CRTAM -8148.0
DDX58 -8149.0
IGLV3-1 -8150.0
IL9R -8158.0
ORMDL3 -8162.0
IL2RG -8168.0
DAB2IP -8176.0
GLMN -8191.0
NFATC3 -8193.0
POLR3D -8194.0
TRIM2 -8223.0
SMURF2 -8254.0
CD47 -8257.0
ZEB1 -8311.0
RAG1 -8312.0
TRAV29DV5 -8326.0
IGLV3-21 -8327.0
IGKV1-16 -8350.0
ATP6V0E2 -8351.0
KCTD7 -8365.0
IFIT1 -8377.0
IFIT2 -8415.0
LGMN -8451.0
RNF138 -8452.0
KIF2A -8455.0
PLCG1 -8497.0
IL5RA -8505.0
IGHV3-33 -8574.0
EVL -8581.0
IGLV2-14 -8599.0
TNFRSF13B -8601.0
TP53 -8613.0
IL12RB2 -8661.0
ZAP70 -8662.0
TRBC1 -8666.0
SPTBN1 -8685.0
RPLP0 -8691.0
NUP160 -8699.0
FGF9 -8705.0
CLEC2D -8716.0
RPS27A -8722.0
KLRC1 -8730.0
CD79A -8733.0
CD3D -8747.0
IFIT5 -8748.0
BTN3A2 -8750.0
DUSP16 -8751.0
LNX1 -8755.0
EDA -8759.0
AKT3 -8761.0
ERBB2 -8774.0
IGLV2-18 -8778.0
LTA -8783.0
SEH1L -8792.0
NUP107 -8801.0
NCK1 -8821.0
HERC6 -8828.0
PTGS2 -8841.0
NLRC3 -8850.0
KIF22 -8858.0
CUL1 -8878.0
LMO7 -8894.0
SLAMF6 -8918.0
HLA-DOA -8929.0
FASLG -8936.0
TNFRSF4 -8948.0
IGLV5-45 -8955.0
KIF3A -8957.0
IGLV6-57 -8979.0
PRR5 -9001.0
DZIP3 -9019.0
HLA-DQB2 -9021.0
RHOF -9031.0
CARD11 -9047.0
NRG1 -9069.0
CBLB -9078.0
FBXO4 -9121.0
CD160 -9124.0
CD3G -9125.0
PDE3B -9128.0
HSP90AB1 -9152.0
LAT -9159.0
HSPA8 -9166.0
GNLY -9182.0
CCL3 -9190.0
ALOX15 -9193.0
TRIM35 -9209.0
HMOX2 -9212.0
IL32 -9229.0
ITK -9231.0
FCER1A -9235.0
NEFL -9236.0
TNFSF8 -9241.0
STAT4 -9273.0
IL24 -9274.0
EDAR -9284.0
RASGRF2 -9300.0
TRIM32 -9302.0
DSC1 -9305.0
PIK3R1 -9306.0
UBE2Q2 -9313.0
CD34 -9323.0
TNFRSF18 -9325.0
TRAC -9330.0
GBP4 -9342.0
EIF4A2 -9355.0
CD3E -9378.0
CD40LG -9383.0
EEF1A1 -9389.0
ANAPC1 -9394.0
TRAV19 -9396.0
ICOS -9398.0
STAT1 -9404.0
NCR1 -9406.0
HLA-DQA2 -9407.0
LTB -9415.0
PDCD4 -9417.0
MYC -9418.0
NUP88 -9430.0
IGKV3-11 -9443.0
CAMK2D -9460.0
RNF125 -9466.0
FLT3LG -9470.0
PTPN4 -9478.0
CYLD -9484.0
LCK -9485.0
POLR3H -9488.0
HSPA9 -9492.0
TLR3 -9494.0
CD247 -9497.0
ATP8A1 -9501.0
SPTAN1 -9516.0
RASGRP1 -9519.0
CFH -9525.0
GBP5 -9526.0
KLHL25 -9528.0
TRAT1 -9546.0
TXK -9555.0
MEX3C -9561.0
DLG3 -9574.0
GATA3 -9575.0
PEBP1 -9578.0
KLHL3 -9584.0
RORA -9585.0
FBXO32 -9595.0
IL23A -9600.0
PLD4 -9601.0
KLRF1 -9605.0
MALT1 -9614.0
THEM4 -9622.0
ICAM2 -9623.0
WWP1 -9624.0
NUP35 -9626.0
CD200R1 -9627.0
RASA3 -9629.0
PRKCQ -9643.0
CTSF -9652.0
IL2RB -9654.0
CCT2 -9661.0
PJA1 -9662.0
NFATC2 -9680.0
SH2D1B -9688.0
ABCE1 -9698.0
FBXO31 -9707.0
TNFRSF25 -9711.0
BIRC3 -9718.0
TRBV12-3 -9724.0
FBXL16 -9728.0
PRKACB -9741.0
FOXO1 -9743.0
CD96 -9792.0
PDGFB -9807.0
CD27 -9814.0
NDC1 -9817.0
SIGLEC6 -9821.0
KLRB1 -9834.0
KIT -9844.0
SH2D1A -9847.0
IMPDH2 -9848.0
KIF5C -9849.0
CD1C -9851.0
CD28 -9875.0
IL7R -9876.0
CCR6 -9877.0
RORC -9883.0


FCGR activation

FCGR activation
361
set FCGR activation
setSize 76
pANOVA 5.44e-08
s.dist -0.361
p.adjustANOVA 1.54e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
CD247 -9497
IGKV3-11 -9443
CD3G -9125
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
IGKV3-15 -7683
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
IGLV7-46 -6955
IGHV3-53 -6692

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CD247 -9497
IGKV3-11 -9443
CD3G -9125
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
IGKV3-15 -7683
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
IGLV7-46 -6955
IGHV3-53 -6692
FYN -6619
IGHV4-34 -6614
IGHV2-5 -6583
IGHV3-48 -5881
IGLC7 -5764
YES1 -5662
IGLV3-27 -5637
IGHV3-23 -5636
IGLV8-61 -5601
SRC -5527
IGHV1-2 -5526
IGLV1-51 -5296
IGKC -5232
IGHV3-7 -5228
IGLC2 -5138
IGKV3-20 -5082
IGKV1-33 -4953
IGHV4-39 -4884
IGHV3-30 -4685
IGLV1-47 -4485
IGKV1-12 -4392
IGKV2-28 -4281
IGLC1 -4280
IGHV2-70 -4223
IGHG3 -4128
IGHV3-11 -3626
IGHV1-46 -3558
IGLV4-69 -3305
IGHG2 -3113
IGLV1-40 -3024
IGKV2-30 -2958
IGKV1-17 -2929
IGHV4-59 -2340
IGLV1-36 -2214
IGLV3-25 -1935
IGHV3-13 -1600
IGHG1 -1504
IGLV1-44 -1090
IGHG4 -760
IGKV2D-28 -728
IGLC3 -403
IGKV3D-20 -305
IGLV10-54 -276
IGLV2-23 1244
IGKV5-2 3051
IGLV2-11 3601
IGKV1D-39 3771
IGLV7-43 7123
IGKV1-39 9771
SYK 10086
FCGR2A 10355
LYN 10893
FCGR3A 11056
FCGR1A 11256
HCK 11416
FGR 11610


FCERI mediated Ca+2 mobilization

FCERI mediated Ca+2 mobilization
358
set FCERI mediated Ca+2 mobilization
setSize 89
pANOVA 5.89e-08
s.dist -0.332
p.adjustANOVA 1.64e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
NFATC2 -9680
TXK -9555
IGKV3-11 -9443
ITK -9231
LAT -9159
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
PLCG1 -8497
IGKV1-16 -8350
IGLV3-21 -8327
NFATC3 -8193
IGLV3-1 -8150
IGKV3-15 -7683
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NFATC2 -9680
TXK -9555
IGKV3-11 -9443
ITK -9231
LAT -9159
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
PLCG1 -8497
IGKV1-16 -8350
IGLV3-21 -8327
NFATC3 -8193
IGLV3-1 -8150
IGKV3-15 -7683
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
IGLV7-46 -6955
IGHV3-53 -6692
IGHV4-34 -6614
IGHV2-5 -6583
GRAP2 -6236
IGHE -6130
IGHV3-48 -5881
IGLC7 -5764
ITPR3 -5727
IGLV3-27 -5637
IGHV3-23 -5636
IGLV8-61 -5601
IGHV1-2 -5526
IGLV1-51 -5296
IGKC -5232
IGHV3-7 -5228
CALM1 -5150
IGLC2 -5138
IGKV3-20 -5082
IGKV1-33 -4953
IGHV4-39 -4884
IGHV3-30 -4685
NFATC1 -4523
IGLV1-47 -4485
IGKV1-12 -4392
IGKV2-28 -4281
IGLC1 -4280
IGHV2-70 -4223
ITPR1 -3809
IGHV3-11 -3626
IGHV1-46 -3558
IGLV4-69 -3305
SOS1 -3263
IGLV1-40 -3024
IGKV2-30 -2958
IGKV1-17 -2929
IGHV4-59 -2340
IGLV1-36 -2214
IGLV3-25 -1935
IGHV3-13 -1600
IGLV1-44 -1090
IGKV2D-28 -728
PPP3CA -429
IGLC3 -403
IGKV3D-20 -305
IGLV10-54 -276
PPP3R1 308
LCP2 514
IGLV2-23 1244
PPP3CB 2367
IGKV5-2 3051
IGLV2-11 3601
IGKV1D-39 3771
AHCYL1 4099
VAV3 5645
ITPR2 6136
IGLV7-43 7123
VAV2 7476
SHC1 7938
IGKV1-39 9771
SYK 10086
VAV1 10149
PLCG2 10376
TEC 10815
LYN 10893
GRB2 10925
BTK 11379


Creation of C4 and C2 activators

Creation of C4 and C2 activators
216
set Creation of C4 and C2 activators
setSize 71
pANOVA 9.77e-08
s.dist -0.366
p.adjustANOVA 2.66e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
IGKV3-11 -9443
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
IGKV3-15 -7683
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
IGLV7-46 -6955
IGHV3-53 -6692
IGHV4-34 -6614
IGHV2-5 -6583

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IGKV3-11 -9443
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
IGKV3-15 -7683
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
IGLV7-46 -6955
IGHV3-53 -6692
IGHV4-34 -6614
IGHV2-5 -6583
IGHV3-48 -5881
IGLC7 -5764
IGLV3-27 -5637
IGHV3-23 -5636
IGLV8-61 -5601
IGHV1-2 -5526
IGLV1-51 -5296
IGKC -5232
IGHV3-7 -5228
IGLC2 -5138
IGKV3-20 -5082
IGKV1-33 -4953
IGHV4-39 -4884
IGHV3-30 -4685
IGLV1-47 -4485
IGKV1-12 -4392
IGKV2-28 -4281
IGLC1 -4280
IGHV2-70 -4223
IGHG3 -4128
IGHV3-11 -3626
IGHV1-46 -3558
IGLV4-69 -3305
IGHG2 -3113
IGLV1-40 -3024
IGKV2-30 -2958
IGKV1-17 -2929
IGHV4-59 -2340
IGLV1-36 -2214
IGLV3-25 -1935
IGHV3-13 -1600
IGHG1 -1504
IGLV1-44 -1090
IGHG4 -760
IGKV2D-28 -728
IGLC3 -403
MASP2 -330
IGKV3D-20 -305
IGLV10-54 -276
IGLV2-23 1244
C1S 2813
IGKV5-2 3051
IGLV2-11 3601
IGKV1D-39 3771
C1R 4413
IGLV7-43 7123
FCN1 9194
IGKV1-39 9771
C1QA 11453
C1QC 11693
C1QB 11723


Extension of Telomeres

Extension of Telomeres
354
set Extension of Telomeres
setSize 51
pANOVA 1.09e-07
s.dist -0.43
p.adjustANOVA 2.87e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
DKC1 -9835
POLD2 -9742
POLA1 -9660
RPA1 -9657
STN1 -9499
WRN -9097
CHTF18 -8785
RFC3 -8694
LIG1 -8618
PRIM1 -8268
RPA3 -8069
CTC1 -8006
SHQ1 -7860
RUVBL1 -7856
RFC4 -7736
DSCC1 -7671
FEN1 -7122
PCNA -6841
GAR1 -6696
POLA2 -6222

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DKC1 -9835
POLD2 -9742
POLA1 -9660
RPA1 -9657
STN1 -9499
WRN -9097
CHTF18 -8785
RFC3 -8694
LIG1 -8618
PRIM1 -8268
RPA3 -8069
CTC1 -8006
SHQ1 -7860
RUVBL1 -7856
RFC4 -7736
DSCC1 -7671
FEN1 -7122
PCNA -6841
GAR1 -6696
POLA2 -6222
TERT -6124
POT1 -5841
ANKRD28 -5772
NHP2 -5747
PRIM2 -5653
RFC1 -5493
TERF2 -4926
RPA2 -4620
BLM -4432
WRAP53 -4086
DNA2 -4017
RFC5 -3986
ACD -3963
TERF1 -3813
CDK2 -3694
CCNA1 -2231
CCNA2 -1727
PPP6C -1168
TERF2IP -1108
CHTF8 -503
PPP6R3 -249
POLD1 646
TEN1 1027
PIF1 1616
RUVBL2 2364
RFC2 4835
TINF2 5948
RTEL1 7274
POLD4 10344
NOP10 10793
POLD3 11274


Metabolism of non-coding RNA

Metabolism of non-coding RNA
644
set Metabolism of non-coding RNA
setSize 53
pANOVA 1.11e-07
s.dist -0.421
p.adjustANOVA 2.87e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
NDC1 -9817
GEMIN4 -9746
NUP35 -9626
NUP88 -9430
DDX20 -9102
NUP107 -8801
SEH1L -8792
NUP160 -8699
PHAX -8612
NCBP2 -8212
NUP43 -7792
NUP155 -7633
GEMIN5 -7299
NUP188 -7295
NUP205 -7051
SNRPE -6979
WDR77 -6973
SNRPF -6725
GEMIN8 -6108
POM121C -6074

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NDC1 -9817
GEMIN4 -9746
NUP35 -9626
NUP88 -9430
DDX20 -9102
NUP107 -8801
SEH1L -8792
NUP160 -8699
PHAX -8612
NCBP2 -8212
NUP43 -7792
NUP155 -7633
GEMIN5 -7299
NUP188 -7295
NUP205 -7051
SNRPE -6979
WDR77 -6973
SNRPF -6725
GEMIN8 -6108
POM121C -6074
CLNS1A -5864
NUP133 -5674
TGS1 -5399
NUP54 -5340
SNRPD2 -4757
SMN1 -4719
NUP153 -4433
SNRPD3 -4404
NUP210 -4373
TPR -4127
SNRPD1 -3757
SNRPB -3546
NUP93 -3163
RANBP2 -3109
GEMIN6 -2834
NUP42 -2718
POM121 -2295
NUP85 -1717
NUP37 -1424
NUP50 -1242
NCBP1 -1125
GEMIN2 -805
NUP98 175
NUP62 395
AAAS 627
PRMT5 1768
SNRPG 3835
GEMIN7 4800
SNUPN 4907
RAE1 5040
SEC13 6793
NUP58 7628
NUP214 10124


snRNP Assembly

snRNP Assembly
1356
set snRNP Assembly
setSize 53
pANOVA 1.11e-07
s.dist -0.421
p.adjustANOVA 2.87e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
NDC1 -9817
GEMIN4 -9746
NUP35 -9626
NUP88 -9430
DDX20 -9102
NUP107 -8801
SEH1L -8792
NUP160 -8699
PHAX -8612
NCBP2 -8212
NUP43 -7792
NUP155 -7633
GEMIN5 -7299
NUP188 -7295
NUP205 -7051
SNRPE -6979
WDR77 -6973
SNRPF -6725
GEMIN8 -6108
POM121C -6074

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NDC1 -9817
GEMIN4 -9746
NUP35 -9626
NUP88 -9430
DDX20 -9102
NUP107 -8801
SEH1L -8792
NUP160 -8699
PHAX -8612
NCBP2 -8212
NUP43 -7792
NUP155 -7633
GEMIN5 -7299
NUP188 -7295
NUP205 -7051
SNRPE -6979
WDR77 -6973
SNRPF -6725
GEMIN8 -6108
POM121C -6074
CLNS1A -5864
NUP133 -5674
TGS1 -5399
NUP54 -5340
SNRPD2 -4757
SMN1 -4719
NUP153 -4433
SNRPD3 -4404
NUP210 -4373
TPR -4127
SNRPD1 -3757
SNRPB -3546
NUP93 -3163
RANBP2 -3109
GEMIN6 -2834
NUP42 -2718
POM121 -2295
NUP85 -1717
NUP37 -1424
NUP50 -1242
NCBP1 -1125
GEMIN2 -805
NUP98 175
NUP62 395
AAAS 627
PRMT5 1768
SNRPG 3835
GEMIN7 4800
SNUPN 4907
RAE1 5040
SEC13 6793
NUP58 7628
NUP214 10124


DNA strand elongation

DNA strand elongation
245
set DNA strand elongation
setSize 32
pANOVA 1.35e-07
s.dist -0.538
p.adjustANOVA 3.4e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
MCM3 -9769
POLD2 -9742
POLA1 -9660
RPA1 -9657
MCM6 -9297
RFC3 -8694
LIG1 -8618
PRIM1 -8268
GINS4 -8200
RPA3 -8069
RFC4 -7736
MCM7 -7720
MCM4 -7627
MCM2 -7557
FEN1 -7122
PCNA -6841
POLA2 -6222
MCM8 -6138
PRIM2 -5653
CDC45 -5643

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MCM3 -9769
POLD2 -9742
POLA1 -9660
RPA1 -9657
MCM6 -9297
RFC3 -8694
LIG1 -8618
PRIM1 -8268
GINS4 -8200
RPA3 -8069
RFC4 -7736
MCM7 -7720
MCM4 -7627
MCM2 -7557
FEN1 -7122
PCNA -6841
POLA2 -6222
MCM8 -6138
PRIM2 -5653
CDC45 -5643
RFC1 -5493
RPA2 -4620
DNA2 -4017
GINS3 -3998
RFC5 -3986
GINS2 -3279
GINS1 -976
POLD1 646
MCM5 1277
RFC2 4835
POLD4 10344
POLD3 11274


Activation of ATR in response to replication stress

Activation of ATR in response to replication stress
33
set Activation of ATR in response to replication stress
setSize 37
pANOVA 1.91e-07
s.dist -0.495
p.adjustANOVA 4.72e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
MCM3 -9769
RPA1 -9657
RAD1 -9471
MCM6 -9297
RFC3 -8694
DBF4 -8484
ORC2 -8097
ORC5 -8089
RPA3 -8069
RAD17 -7742
RFC4 -7736
MCM7 -7720
MCM4 -7627
ORC3 -7568
MCM2 -7557
MCM10 -6777
MCM8 -6138
CHEK1 -6036
ORC4 -5692
CDC45 -5643

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MCM3 -9769
RPA1 -9657
RAD1 -9471
MCM6 -9297
RFC3 -8694
DBF4 -8484
ORC2 -8097
ORC5 -8089
RPA3 -8069
RAD17 -7742
RFC4 -7736
MCM7 -7720
MCM4 -7627
ORC3 -7568
MCM2 -7557
MCM10 -6777
MCM8 -6138
CHEK1 -6036
ORC4 -5692
CDC45 -5643
CDC6 -5479
ORC1 -5158
RAD9A -5073
RPA2 -4620
RFC5 -3986
CDK2 -3694
ATR -2784
CDC25A -2547
ATRIP -1520
CLSPN -178
CDC7 815
MCM5 1277
CDC25C 1278
HUS1 2327
RFC2 4835
ORC6 8542
RAD9B 8706


Role of LAT2/NTAL/LAB on calcium mobilization

Role of LAT2/NTAL/LAB on calcium mobilization
1016
set Role of LAT2/NTAL/LAB on calcium mobilization
setSize 74
pANOVA 4.04e-07
s.dist -0.341
p.adjustANOVA 9.84e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
IGKV3-11 -9443
PIK3R1 -9306
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
IGKV3-15 -7683
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
IGLV7-46 -6955
IGHV3-53 -6692
FYN -6619

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IGKV3-11 -9443
PIK3R1 -9306
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
IGKV3-15 -7683
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
IGLV7-46 -6955
IGHV3-53 -6692
FYN -6619
IGHV4-34 -6614
IGHV2-5 -6583
IGHE -6130
IGHV3-48 -5881
IGLC7 -5764
IGLV3-27 -5637
IGHV3-23 -5636
IGLV8-61 -5601
IGHV1-2 -5526
IGLV1-51 -5296
IGKC -5232
IGHV3-7 -5228
IGLC2 -5138
IGKV3-20 -5082
IGKV1-33 -4953
IGHV4-39 -4884
IGHV3-30 -4685
IGLV1-47 -4485
IGKV1-12 -4392
IGKV2-28 -4281
IGLC1 -4280
IGHV2-70 -4223
IGHV3-11 -3626
IGHV1-46 -3558
IGLV4-69 -3305
SOS1 -3263
IGLV1-40 -3024
IGKV2-30 -2958
IGKV1-17 -2929
IGHV4-59 -2340
IGLV1-36 -2214
IGLV3-25 -1935
IGHV3-13 -1600
PIK3CA -1131
IGLV1-44 -1090
IGKV2D-28 -728
IGLC3 -403
IGKV3D-20 -305
IGLV10-54 -276
IGLV2-23 1244
IGKV5-2 3051
IGLV2-11 3601
IGKV1D-39 3771
PDPK1 5768
PIK3CB 6109
PIK3R2 6269
IGLV7-43 7123
SHC1 7938
IGKV1-39 9771
SYK 10086
GAB2 10228
LAT2 10791
LYN 10893
GRB2 10925


Chromosome Maintenance

Chromosome Maintenance
179
set Chromosome Maintenance
setSize 105
pANOVA 5.23e-07
s.dist -0.283
p.adjustANOVA 1.25e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
NPM1 -9836
DKC1 -9835
POLD2 -9742
POLA1 -9660
RPA1 -9657
MIS18A -9606
STN1 -9499
CENPH -9233
WRN -9097
CHTF18 -8785
ITGB3BP -8742
RFC3 -8694
LIG1 -8618
CENPM -8299
PRIM1 -8268
POLR2D -8160
RPA3 -8069
CTC1 -8006
SHQ1 -7860
RUVBL1 -7856

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NPM1 -9836
DKC1 -9835
POLD2 -9742
POLA1 -9660
RPA1 -9657
MIS18A -9606
STN1 -9499
CENPH -9233
WRN -9097
CHTF18 -8785
ITGB3BP -8742
RFC3 -8694
LIG1 -8618
CENPM -8299
PRIM1 -8268
POLR2D -8160
RPA3 -8069
CTC1 -8006
SHQ1 -7860
RUVBL1 -7856
RFC4 -7736
CENPQ -7689
DSCC1 -7671
RBBP7 -7322
FEN1 -7122
PCNA -6841
GAR1 -6696
H2BC9 -6264
POLA2 -6222
CENPC -6141
TERT -6124
SMARCA5 -6114
H2AZ2 -5901
POT1 -5841
ANKRD28 -5772
CENPT -5770
NHP2 -5747
PRIM2 -5653
RFC1 -5493
CENPL -5433
POLR2B -5111
TERF2 -4926
RBBP4 -4658
CENPK -4642
RPA2 -4620
BLM -4432
CENPN -4391
WRAP53 -4086
DNA2 -4017
ATRX -4015
RFC5 -3986
ACD -3963
POLR2K -3902
TERF1 -3813
CDK2 -3694
DAXX -3631
POLR2H -3611
RSF1 -2933
CENPU -2720
CENPA -2615
POLR2C -2566
CCNA1 -2231
H2BU1 -2206
H2AC6 -1829
CCNA2 -1727
POLR2I -1599
PPP6C -1168
TERF2IP -1108
HJURP -980
CHTF8 -503
PPP6R3 -249
H2BC15 524
POLD1 646
TEN1 1027
CENPI 1203
PIF1 1616
KNL1 2231
RUVBL2 2364
MIS18BP1 2725
H2AZ1 2960
CENPP 3032
H2BC11 3290
POLR2L 3450
H2BC17 3795
H2BC4 4239
H2BC5 4435
RFC2 4835
POLR2E 5238
POLR2G 5695
POLR2F 5738
CENPO 5838
TINF2 5948
H2BC12 6101
H2BC21 6180
POLR2A 6387
OIP5 6593
CENPW 6896
RTEL1 7274
H3-3A 7624
POLR2J 7983
H2AC20 8783
POLD4 10344
NOP10 10793
POLD3 11274
H2AJ 11606


Metabolism of lipids

Metabolism of lipids
642
set Metabolism of lipids
setSize 626
pANOVA 7.53e-07
s.dist 0.116
p.adjustANOVA 1.77e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
PLBD1 11732
GGT1 11721
TNFAIP8L3 11716
HSD3B7 11681
CYP19A1 11666
VDR 11663
PLA2G15 11650
PPARG 11631
TBXAS1 11623
PLB1 11615
ACOX2 11603
PRKACA 11578
ACAA1 11576
PLIN3 11513
GBA 11490
ASAH1 11411
NEU1 11402
AGPAT2 11396
NCOR2 11380
SBF2 11367

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PLBD1 11732
GGT1 11721
TNFAIP8L3 11716
HSD3B7 11681
CYP19A1 11666
VDR 11663
PLA2G15 11650
PPARG 11631
TBXAS1 11623
PLB1 11615
ACOX2 11603
PRKACA 11578
ACAA1 11576
PLIN3 11513
GBA 11490
ASAH1 11411
NEU1 11402
AGPAT2 11396
NCOR2 11380
SBF2 11367
CD36 11354
ALDH3B1 11330
CYP4F8 11319
PTGR1 11262
GALC 11253
CYP1B1 11248
PISD 11239
GM2A 11237
ACOT9 11230
OLAH 11223
NFYC 11209
INPPL1 11200
TSPO 11171
ALOX5 11153
PITPNM1 11147
CPT2 11145
DHRS7B 11112
GLA 11064
LTA4H 11060
PPT1 11019
MTMR3 10965
ME1 10923
DGAT2 10895
PIK3R6 10890
LPCAT3 10888
FIG4 10857
GLB1 10846
ACOT8 10812
ACSL1 10810
ESRRA 10775
RGL1 10736
PNPLA6 10720
HMGCL 10573
PGS1 10550
MBOAT7 10535
AGPAT4 10530
PLD1 10520
CTSA 10517
SPHK1 10467
SLC25A20 10448
HADHB 10423
ARSB 10406
ACADVL 10394
PLD2 10367
ARF1 10356
SEC24D 10340
APOA2 10312
RXRA 10309
ELOVL1 10305
FADS1 10296
CARM1 10294
CHKA 10281
PLIN2 10280
SRD5A3 10266
LPCAT2 10256
SYNJ1 10251
SGMS2 10239
ACSS3 10234
SRD5A1 10214
DHCR24 10202
PNPLA2 10177
ACAD10 10170
ACOX3 10110
ABHD3 10025
PSAP 10019
PLA2R1 9987
GK 9954
PLA2G4A 9943
DBI 9933
SQLE 9920
MTF1 9903
ACSL4 9884
GLTP 9871
ACER3 9862
ABHD5 9838
DECR1 9806
GPCPD1 9781
OCRL 9709
HACD1 9705
HSD17B4 9667
ACLY 9642
SLC10A2 9631
ELOVL3 9628
FAR1 9626
SLC22A5 9621
ARSA 9608
ANGPTL4 9601
MTMR14 9588
SGPL1 9540
GBA2 9520
SREBF2 9474
ALB 9450
BMX 9422
NR1H2 9385
PLPP3 9343
NCOA6 9341
AGPAT3 9335
PTGES 9282
ORMDL2 9228
SLC44A5 9170
PIAS4 9149
CYP1A2 9123
ABCC3 9051
CDK19 9006
ARNT 9003
STARD3 8910
SPTLC1 8868
SUMF1 8865
MED25 8855
STAR 8828
EP300 8816
EHHADH 8699
ARF3 8602
SMARCD3 8576
FAR2 8541
MBTPS1 8506
ACOX1 8434
HSD11B2 8276
GPD2 8261
ACOT13 8253
TXNRD1 8216
MED8 8164
VAPA 8135
SP1 8056
ACADS 8015
OSBPL2 8006
CSNK2A1 7984
ACACA 7976
INPP5D 7960
LPGAT1 7886
FAM120B 7868
PHOSPHO1 7864
GNPAT 7851
MED20 7833
ABCC1 7821
MED13L 7752
SPHK2 7744
B3GALNT1 7718
PCTP 7682
ALOX5AP 7665
FDFT1 7639
SGMS1 7585
INPP5F 7562
HDAC3 7484
GDE1 7454
SPTLC2 7440
GDPD3 7434
MBOAT1 7374
SMPD2 7372
PTEN 7321
MED18 7308
STS 7289
CYP51A1 7250
FDPS 7240
LRP2 7216
GLB1L 7193
CYP2C9 7142
PIP5K1C 7137
CHPT1 7083
SEC24C 7065
CRAT 6976
GPAT4 6968
PIK3R5 6963
PECR 6943
SEC24A 6928
HEXB 6925
HPGD 6924
GSTM4 6857
ACAA2 6853
TECRL 6844
MBOAT2 6817
GGT5 6798
MTMR10 6797
SLC25A1 6742
CERT1 6718
ACSL3 6699
VAC14 6654
FABP2 6650
PLEKHA4 6624
PI4K2A 6573
CSNK2B 6563
PCYT1A 6533
PIK3CD 6507
MED19 6500
MAPKAPK2 6495
FABP5 6480
ARSD 6436
PLD3 6403
STARD5 6389
PIK3CG 6350
GPX2 6305
PIK3R2 6269
TAZ 6217
ACBD7 6172
ABCD1 6135
PIP5K1B 6118
MOGAT3 6114
PIK3CB 6109
NUDT19 6104
ALAS1 6092
HMGCR 6061
FDXR 6027
NCOA3 6012
INSIG1 6009
ACOT1 5960
CERS2 5958
CPT1A 5921
NCOR1 5849
SLC27A1 5809
GLIPR1 5779
STARD4 5761
PMVK 5667
FADS2 5662
HSD17B2 5602
ACADL 5599
CREBBP 5593
IDI1 5566
CERS5 5565
ACOXL 5562
MED11 5475
NR1H3 5458
DGAT1 5440
SAMD8 5427
CERS3 5413
LBR 5389
ABCA1 5327
ACSF3 5311
ACOT11 5283
SLC27A5 5244
PPP1CA 5239
LPCAT1 5222
ACHE 5184
MTMR4 5076
GPX1 5066
CSNK1G2 5052
MED12 5009
PNPLA8 4985
GPAT3 4900
STARD3NL 4784
TMEM86B 4762
MTMR6 4681
ACSF2 4559
SAR1B 4545
SEC24B 4410
CDS2 4384
HSD17B13 4364
LIPH 4339
GPAT2 4334
PTPMT1 4332
CSNK2A2 4323
NCOA2 4313
SLC27A3 4310
CDIPT 4290
ARNTL 4270
ALOX15B 4225
MTMR7 4212
PCYT1B 4192
ABHD4 4114
RXRB 4044
PTGR2 4015
CHKB 4008
PIK3C2G 3967
DHCR7 3934
OSBPL9 3917
ENPP6 3895
AGPAT1 3865
FHL2 3842
CYP4F22 3837
INSIG2 3806
RAB5A 3708
CDK8 3675
DPEP2 3646
TBL1X 3644
MMUT 3606
ARV1 3603
CPT1B 3580
STARD7 3569
PLIN1 3541
PIKFYVE 3494
PPM1L 3475
CRLS1 3412
AHRR 3378
TNFAIP8L2 3297
PI4KB 3280
NSDHL 3256
PPARGC1B 3227
HSD17B11 3171
PLPP2 3145
PLA2G4D 3128
PPP1CC 2943
RAB14 2942
PIP5K1A 2891
OSBPL8 2868
CYP4F3 2865
HTD2 2862
PPP1CB 2847
SIN3B 2807
PIK3R3 2799
PI4KA 2752
SCD 2719
SLC44A1 2702
GPS2 2679
PEX11A 2665
MED24 2654
HSD17B12 2614
AHR 2519
NUDT7 2499
MED26 2492
MTMR9 2484
PTDSS2 2463
THRAP3 2381
ELOVL5 2295
GPD1 2270
HADHA 2215
HELZ2 2199
PRKD3 2166
ACBD5 2154
CERS6 2026
MED16 2006
INPP4A 1957
UGCG 1870
SEC23A 1838
HACD4 1751
NCOA1 1719
RUFY1 1664
MED14 1629
AACS 1545
ACSM6 1542
MVD 1475
AKR1C1 1452
TBL1XR1 1405
CYP27A1 1404
PLEKHA6 1400
PRKD2 1342
MTM1 1316
TIAM2 1228
CEPT1 1199
MCAT 1143
FITM1 1110
SLC10A1 1103
GPX4 1096
MLYCD 1084
MCEE 1072
CYP46A1 976
PPARA 838
PITPNM3 834
SCD5 767
FABP3 733
SPTLC3 728
INPP5K 648
NFYA 629
CPNE7 617
MED28 603
UBE2I 587
ASAH2 509
PIP4K2C 477
ALOX12 452
MED23 403
MED15 383
DEGS2 332
CBR4 299
AGPS 189
CHD9 159
ALDH3A2 149
DPEP3 74
SLC44A2 34
MED27 -50
SPNS2 -88
KPNB1 -109
PLEKHA2 -120
NEU3 -139
CPNE3 -215
AKR1B15 -216
MSMO1 -261
MED4 -312
PNPLA4 -342
DEGS1 -381
DECR2 -402
HILPDA -426
HEXA -442
PTDSS1 -451
PLAAT2 -465
CBR1 -489
MED7 -535
HSD17B1 -560
ORMDL1 -570
G0S2 -637
PLEKHA5 -653
POMC -667
PIK3C2A -690
SREBF1 -751
OXCT2 -806
LPCAT4 -874
LTC4S -942
CPTP -943
ECI1 -1005
MID1IP1 -1039
OSBPL5 -1082
PPARGC1A -1095
TNFRSF21 -1106
PIK3CA -1131
CPNE1 -1135
PTGS1 -1218
SUMO2 -1222
ACBD4 -1238
SMPD1 -1245
PRKAG2 -1248
CYP7B1 -1296
TRIB3 -1365
ACSL5 -1429
FA2H -1493
SC5D -1554
GDPD1 -1563
ACSBG1 -1570
STARD10 -1646
HMGCS1 -1692
SCP2 -1758
MTMR12 -1965
PEMT -1971
MED31 -1991
MED22 -2030
OSBPL1A -2043
CYP2R1 -2101
ACAD11 -2205
FDX2 -2219
SGPP1 -2239
MED9 -2378
PLEKHA8 -2385
MECR -2419
PNPLA7 -2531
MVK -2549
PLA2G4C -2609
SCAP -2643
OSBPL6 -2711
FDX1 -2797
MTMR8 -2809
AKR1C2 -2830
PHYH -2835
ACBD6 -2897
MBTPS2 -2996
ABCB4 -3042
UGT8 -3063
LPIN3 -3221
PIK3C3 -3291
PLAAT3 -3319
PTGES2 -3328
NDUFAB1 -3353
CLOCK -3387
PCCA -3394
ETNK1 -3399
RAB4A -3411
MTMR1 -3412
ELOVL7 -3469
MED21 -3470
AMACR -3568
PON2 -3576
NPAS2 -3613
PLEKHA3 -3618
MED13 -3648
PTGDS -3658
MGLL -3689
CAV1 -3722
PLA2G2D -3749
NRF1 -3790
ACAT1 -3857
OSBP -3884
PITPNM2 -3905
MFSD2A -3939
LCLAT1 -4107
MED29 -4118
MED1 -4211
PRKAB2 -4214
PLA2G10 -4307
PTGES3 -4326
ALOX12B -4341
PIK3R4 -4411
SMPD4 -4435
CERS4 -4436
TM7SF2 -4654
GGPS1 -4847
ACOT2 -4870
INPP5E -4968
ECHS1 -5038
MIGA2 -5102
ACER2 -5109
OSBPL7 -5159
GDPD5 -5164
ARSG -5175
VAPB -5205
PLA2G6 -5218
HSD17B7 -5257
ELOVL6 -5270
HSD17B8 -5324
ACADM -5375
TGS1 -5399
DDHD1 -5419
LPIN1 -5449
ACACB -5540
ARSJ -5583
EBP -5588
PLAAT1 -5626
AKR1C3 -5675
MED17 -5686
MED30 -5762
PTPN13 -5867
PITPNB -5877
MTMR2 -5898
PCCB -5905
PIP4K2A -5911
PLPP6 -5987
TNFAIP8L1 -5990
SBF1 -6038
PLA2G4B -6050
ETNK2 -6234
CDS1 -6290
SPTSSA -6313
HACD2 -6316
SMPD3 -6354
SGPP2 -6462
CUBN -6516
LSS -6535
SUMF2 -6604
MMAA -6672
LPIN2 -6679
CYP2D6 -6681
FASN -6745
ACP6 -6806
TSPOAP1 -6834
GRHL1 -6837
ACOT4 -6846
CYP2J2 -6877
PLA2G12A -6906
PCYT2 -6914
MED6 -6963
ACOT7 -6970
TECR -7046
AGK -7086
CCNC -7102
ACER1 -7124
SLC27A2 -7272
FAAH -7318
ACSM3 -7334
PPARD -7353
PPT2 -7431
PIP4K2B -7436
MED10 -7505
PLPP1 -7523
RAN -7577
OSBPL10 -7706
SACM1L -7708
CERK -7750
FITM2 -7798
SLC25A17 -7846
MIGA1 -8025
GPAM -8085
SELENOI -8101
MORC2 -8151
ORMDL3 -8162
GPD1L -8170
CYP27B1 -8188
LIPE -8197
ACAT2 -8218
PRXL2B -8392
SPTSSB -8407
OSBPL3 -8411
LGMN -8451
BDH2 -8531
HADH -8583
THEM5 -8623
PIK3C2B -8804
DDHD2 -8806
PTGS2 -8841
ESYT2 -8853
SIN3A -8913
HACL1 -8940
TNFAIP8 -9158
ALOX15 -9193
CYP2U1 -9194
BDH1 -9296
PIK3R1 -9306
ECI2 -9315
NR1D1 -9318
ESYT1 -9319
PLAAT4 -9335
PI4K2B -9377
HACD3 -9416
FAAH2 -9423
CYP2E1 -9427
CROT -9462
AKR1B1 -9480
OXCT1 -9510
AGPAT5 -9535
ACSL6 -9557
RORA -9585
PLD6 -9599
PLD4 -9601
SYNJ2 -9603
THEM4 -9622
ARSK -9656
NFYB -9659
PLEKHA1 -9709
KDSR -9733
PRKACB -9741
INPP4B -9752
EPHX2 -9770
ELOVL4 -9859


Telomere C-strand (Lagging Strand) Synthesis

Telomere C-strand (Lagging Strand) Synthesis
1219
set Telomere C-strand (Lagging Strand) Synthesis
setSize 34
pANOVA 7.85e-07
s.dist -0.489
p.adjustANOVA 1.81e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
POLD2 -9742
POLA1 -9660
RPA1 -9657
STN1 -9499
WRN -9097
CHTF18 -8785
RFC3 -8694
LIG1 -8618
PRIM1 -8268
RPA3 -8069
CTC1 -8006
RFC4 -7736
DSCC1 -7671
FEN1 -7122
PCNA -6841
POLA2 -6222
POT1 -5841
PRIM2 -5653
RFC1 -5493
TERF2 -4926

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
POLD2 -9742
POLA1 -9660
RPA1 -9657
STN1 -9499
WRN -9097
CHTF18 -8785
RFC3 -8694
LIG1 -8618
PRIM1 -8268
RPA3 -8069
CTC1 -8006
RFC4 -7736
DSCC1 -7671
FEN1 -7122
PCNA -6841
POLA2 -6222
POT1 -5841
PRIM2 -5653
RFC1 -5493
TERF2 -4926
RPA2 -4620
BLM -4432
DNA2 -4017
RFC5 -3986
ACD -3963
TERF1 -3813
TERF2IP -1108
CHTF8 -503
POLD1 646
TEN1 1027
RFC2 4835
TINF2 5948
POLD4 10344
POLD3 11274


Antigen activates B Cell Receptor (BCR) leading to generation of second messengers

Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
72
set Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
setSize 84
pANOVA 9.73e-07
s.dist -0.309
p.adjustANOVA 2.21e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
IGKV3-11 -9443
PIK3R1 -9306
IGLV6-57 -8979
NCK1 -8821
CD79A -8733
IGLV2-14 -8599
IGHV3-33 -8574
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
TRPC1 -7994
BLK -7991
IGKV3-15 -7683
IGHV1-69 -7589
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
ORAI1 -7149
CD79B -7082

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IGKV3-11 -9443
PIK3R1 -9306
IGLV6-57 -8979
NCK1 -8821
CD79A -8733
IGLV2-14 -8599
IGHV3-33 -8574
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
TRPC1 -7994
BLK -7991
IGKV3-15 -7683
IGHV1-69 -7589
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
ORAI1 -7149
CD79B -7082
CD22 -6705
IGHV3-53 -6692
FYN -6619
IGHV4-34 -6614
IGHV2-5 -6583
BLNK -6523
IGHV3-48 -5881
IGLC7 -5764
ITPR3 -5727
IGLV3-27 -5637
IGHV3-23 -5636
IGHV1-2 -5526
IGLV1-51 -5296
IGKC -5232
IGHV3-7 -5228
IGHD -5224
CALM1 -5150
IGHM -5149
IGLC2 -5138
IGKV3-20 -5082
IGKV1-33 -4953
IGHV4-39 -4884
IGHV3-30 -4685
IGLV1-47 -4485
IGKV1-12 -4392
IGKV2-28 -4281
IGLC1 -4280
IGHV2-70 -4223
CD19 -3919
ITPR1 -3809
IGHV3-11 -3626
IGHV1-46 -3558
SOS1 -3263
IGLV1-40 -3024
IGKV2-30 -2958
IGKV1-17 -2929
IGHV4-59 -2340
IGLV3-25 -1935
IGHV3-13 -1600
IGLV1-44 -1090
IGKV2D-28 -728
IGLC3 -403
IGKV3D-20 -305
DAPP1 450
IGLV2-23 1244
SH3KBP1 1675
IGKV5-2 3051
IGLV2-11 3601
IGKV1D-39 3771
AHCYL1 4099
ORAI2 5982
ITPR2 6136
PIK3CD 6507
IGLV7-43 7123
STIM1 8775
IGKV1-39 9771
SYK 10086
VAV1 10149
PLCG2 10376
PIK3AP1 10723
LYN 10893
GRB2 10925
PTPN6 11254
BTK 11379


Role of phospholipids in phagocytosis

Role of phospholipids in phagocytosis
1017
set Role of phospholipids in phagocytosis
setSize 88
pANOVA 1.17e-06
s.dist -0.3
p.adjustANOVA 2.61e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
PLD4 -9601
CD247 -9497
IGKV3-11 -9443
PIK3R1 -9306
CD3G -9125
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
PLCG1 -8497
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
IGKV3-15 -7683
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PLD4 -9601
CD247 -9497
IGKV3-11 -9443
PIK3R1 -9306
CD3G -9125
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
PLCG1 -8497
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
IGKV3-15 -7683
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
IGLV7-46 -6955
IGHV3-53 -6692
IGHV4-34 -6614
IGHV2-5 -6583
IGHV3-48 -5881
IGLC7 -5764
ITPR3 -5727
IGLV3-27 -5637
IGHV3-23 -5636
IGLV8-61 -5601
IGHV1-2 -5526
IGLV1-51 -5296
IGKC -5232
IGHV3-7 -5228
PLA2G6 -5218
IGLC2 -5138
IGKV3-20 -5082
IGKV1-33 -4953
IGHV4-39 -4884
IGHV3-30 -4685
IGLV1-47 -4485
IGKV1-12 -4392
IGKV2-28 -4281
IGLC1 -4280
IGHV2-70 -4223
IGHG3 -4128
ITPR1 -3809
IGHV3-11 -3626
IGHV1-46 -3558
IGLV4-69 -3305
IGHG2 -3113
IGLV1-40 -3024
IGKV2-30 -2958
IGKV1-17 -2929
IGHV4-59 -2340
IGLV1-36 -2214
IGLV3-25 -1935
IGHV3-13 -1600
IGHG1 -1504
PIK3CA -1131
IGLV1-44 -1090
IGHG4 -760
IGKV2D-28 -728
IGLC3 -403
IGKV3D-20 -305
IGLV10-54 -276
PLPP5 750
IGLV2-23 1244
IGKV5-2 3051
IGLV2-11 3601
IGKV1D-39 3771
AHCYL1 4099
PIK3CB 6109
ITPR2 6136
PIK3R2 6269
PLD3 6403
IGLV7-43 7123
PRKCE 9268
IGKV1-39 9771
SYK 10086
FCGR2A 10355
PLD2 10367
PLCG2 10376
PLD1 10520
FCGR3A 11056
FCGR1A 11256
PRKCD 11506


Vesicle-mediated transport

Vesicle-mediated transport
1312
set Vesicle-mediated transport
setSize 648
pANOVA 1.24e-06
s.dist 0.112
p.adjustANOVA 2.72e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
MARCO 11713
AP2A1 11707
STAB1 11698
RIN1 11696
SERPINA1 11685
F5 11617
GNS 11592
HP 11572
PLIN3 11513
COG7 11491
AMPH 11449
ULK1 11434
SBF2 11367
CD36 11354
BLOC1S1 11348
COPG1 11346
CUX1 11328
CD163 11297
ARPC1A 11206
LRP1 11120

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MARCO 11713
AP2A1 11707
STAB1 11698
RIN1 11696
SERPINA1 11685
F5 11617
GNS 11592
HP 11572
PLIN3 11513
COG7 11491
AMPH 11449
ULK1 11434
SBF2 11367
CD36 11354
BLOC1S1 11348
COPG1 11346
CUX1 11328
CD163 11297
ARPC1A 11206
LRP1 11120
DENND3 11092
RIN2 11027
ARRB2 11021
GORASP1 10996
EPN1 10994
AP1B1 10946
ITSN1 10929
GRB2 10925
RAC1 10907
RAB10 10903
SNX18 10894
DAB2 10889
RAB39A 10887
GJD3 10882
TBC1D2 10859
STX10 10849
AP1S1 10842
VPS37C 10801
GRK3 10799
CTSZ 10773
CD55 10741
SCARB2 10644
CHMP2A 10625
CHMP4B 10624
TBC1D14 10488
VPS25 10487
DCTN2 10458
AP2A2 10434
CYTH4 10395
ARF1 10356
RAB13 10352
FTL 10348
SEC24D 10340
GGA1 10328
GALNT2 10321
PREB 10297
SYNJ1 10251
RAB5C 10197
COL7A1 10174
KIF1C 10156
AP1M1 10145
IGF2R 10077
MAN1A1 10070
ACTR1A 10067
AP4M1 10058
ARPC5 10048
RAB31 10045
RAB32 10038
DENND5A 10034
SORT1 10018
TBC1D10B 9956
PLA2G4A 9943
CPD 9940
HGS 9939
TGFA 9932
RAB1A 9919
MON1B 9913
YWHAG 9892
EXOC1 9891
NSF 9858
HIP1 9850
COPA 9848
TBC1D1 9842
RALGAPA2 9821
PICALM 9814
IGKV1-39 9771
DNM2 9736
TGOLN2 9729
GOLIM4 9711
OCRL 9709
MVB12A 9695
CHMP5 9670
MYO5A 9640
KIF1B 9632
GGA3 9615
TMED9 9614
ARF5 9584
KDELR1 9578
LDLR 9568
VAMP7 9561
TRAPPC12 9530
CTSC 9524
SNX2 9523
MAN2A2 9508
AP2S1 9504
ARPC3 9484
DCTN4 9451
ALB 9450
RAB1B 9447
GRK2 9446
DENND4B 9426
CLTC 9346
UBAP1 9339
AGPAT3 9335
GAK 9326
DCTN6 9325
SEC16B 9315
SH3GL1 9314
AGFG1 9305
RAB7A 9295
NAA38 9238
ARPC4 9223
DCTN1 9214
ARPC2 9212
SCGB3A2 9181
ARF4 9156
EXOC6 9137
EXOC7 9098
PRKAB1 9059
COG4 9044
CLTCL1 9020
LMAN2 8931
TRAPPC1 8880
PACSIN2 8869
CCZ1 8831
REPS2 8795
COPE 8787
NAPG 8778
CBL 8765
HPS1 8755
COPS7A 8689
COPG2 8671
BICD2 8632
SNAPIN 8619
ARF3 8602
CAPZB 8593
SNAP29 8589
YWHAE 8584
RIC1 8493
SNF8 8478
NAPA 8477
ALS2 8433
NEDD8 8396
GOLGA2 8366
VPS53 8331
GOLGA1 8280
CLTB 8275
DENND1A 8266
STX4 8182
YWHAH 8129
DYNC1LI2 8092
STX5 8070
CAPZA1 8032
VAMP3 8012
CAPZA2 7999
KLC1 7957
GABARAP 7950
RAB27A 7933
SCFD1 7929
PPP6R1 7922
DCTN3 7885
DYNC1LI1 7881
TFG 7873
SEC16A 7812
RAB36 7803
VTI1A 7757
CLTA 7680
RAB7B 7637
TOR1B 7635
RAB6A 7579
TOR1A 7549
CSNK1D 7458
ACTR2 7352
AP2M1 7323
PRKAG1 7316
MVB12B 7291
EXOC3 7224
LRP2 7216
EPS15L1 7199
PIP5K1C 7137
IGLV7-43 7123
SYT11 7091
SEC24C 7065
TRAPPC3 7024
SEC24A 6928
FCHO2 6921
STXBP3 6903
TRAPPC11 6868
SEC13 6793
DNASE2 6747
ARFGAP2 6724
COPB2 6710
CHMP3 6707
CHMP6 6694
CHMP4A 6691
STX18 6681
ACTR3 6644
COL4A2 6618
VPS37B 6524
GDI1 6479
YKT6 6467
FTH1 6366
KIF5B 6360
CNIH2 6334
MYH9 6290
GBF1 6282
COPB1 6181
AKT1 6133
SNX5 6119
SYT2 6082
ARFGAP1 6078
ITSN2 6016
KIF13B 6004
KIF6 5970
VPS52 5896
GJC1 5867
ARRB1 5865
AVPR2 5844
DNM1 5834
GAPVD1 5827
VPS37A 5731
DYNC1I2 5729
TBC1D24 5666
TSG101 5627
RACGAP1 5554
RABEPK 5549
STAB2 5526
SPTBN5 5455
TBC1D7 5417
AP3B1 5406
AKT2 5390
STX6 5374
GDI2 5257
YIPF6 5187
SURF4 5135
KIF23 5122
RHOQ 5105
TBC1D16 5070
CALR 4966
KDELR2 4945
RAB5B 4935
TJP1 4924
RAB35 4902
TRAPPC8 4901
UBC 4874
RAB8B 4792
F8 4773
CCZ1B 4768
STAM2 4752
GOLGA5 4747
TSC2 4664
REPS1 4640
TRAPPC5 4592
SAR1B 4545
RABGEF1 4500
VPS45 4436
SEC24B 4410
PUM1 4404
KIF3B 4392
DENND2C 4372
RAB18 4366
SNAP23 4343
MIA2 4301
KIF3C 4286
VAMP8 4250
ACTR10 4228
SYT1 4178
RABGAP1 4163
CYTH2 4110
FNBP1L 4083
RAB8A 3907
NECAP1 3901
TMEM115 3887
TBC1D13 3874
USP6NL 3870
GABARAPL2 3855
EPS15 3853
AP1G1 3828
TF 3776
IGKV1D-39 3771
TMED3 3759
PAFAH1B1 3738
RAB5A 3708
MAP1LC3B 3686
NAPB 3641
DENND1C 3637
TPD52L1 3634
IGLV2-11 3601
RAB11B 3598
KIF9 3582
EXOC4 3461
SPTB 3448
ARFGAP3 3442
GGA2 3422
MADD 3395
APP 3315
RAB3GAP2 3311
RGP1 3262
MSR1 3252
KLC3 3246
DYNLL1 3185
TBC1D8B 3146
AP3S1 3106
COPS5 3077
IGKV5-2 3051
TFRC 3047
TSC1 3041
FZD4 3002
RAB14 2942
COPZ1 2925
KIF18B 2844
SNX9 2815
AP4E1 2808
GOSR2 2697
RAB43 2624
GALNT1 2613
COL1A2 2609
RAB3GAP1 2608
SFN 2567
TRAPPC13 2482
DENND6B 2457
GJC2 2387
PAFAH1B2 2356
SEC22B 2167
CFTR 2137
TBC1D3 2123
ANKRD27 2095
TRAPPC2L 2058
YWHAB 2038
SEC31A 2016
RAB21 2011
CENPE 1952
STX16 1904
SEC23A 1838
KIFC2 1820
AP1S3 1783
VTA1 1763
APOL1 1736
TBC1D20 1725
ARCN1 1716
SH3KBP1 1675
LMAN2L 1671
VPS54 1639
SPTA1 1589
TRAPPC9 1554
RAB41 1492
RAB11A 1334
AP4B1 1250
IGLV2-23 1244
APOE 1230
RAB3A 1226
DYNC1I1 1191
CLINT1 1115
KIF2C 1104
KIAA0319 1066
TMED2 965
AREG 932
MON1A 905
COPS6 898
VPS28 893
DNAJC6 888
KIF19 826
DENND6A 816
KDELR3 810
RAB38 764
ANK1 741
COG5 706
MCFD2 660
SPTBN2 565
EXOC8 537
AP1G2 471
TRAPPC10 441
EREG 410
KIF27 249
COPS7B 246
EGF 238
KIF18A 102
STON1 7
VAMP4 -18
HBB -79
USO1 -110
SCARB1 -168
FCHO1 -228
PPP6R3 -249
DNM3 -250
IGLV10-54 -276
IGKV3D-20 -305
NECAP2 -326
ASPSCR1 -351
CHMP2B -392
HBEGF -398
IGLC3 -403
TBC1D25 -415
TRAPPC6B -434
POLG -445
TMF1 -467
KIF21B -476
COPS2 -505
ACBD3 -610
UBQLN1 -627
VPS4B -630
RAB3IL1 -640
YWHAZ -647
RALGAPB -650
RAB12 -684
PIK3C2A -690
IGKV2D-28 -728
COPS3 -762
TBC1D10A -766
ARF6 -848
HBA1 -867
DCTN5 -898
NBAS -985
DYNC1H1 -1040
IGLV1-44 -1090
UBQLN2 -1116
EPN2 -1150
PPP6C -1168
KLC4 -1189
RAB33B -1199
PRKAG2 -1248
RAB3IP -1300
TRAPPC4 -1304
TMED7 -1318
COG8 -1340
WASL -1370
TBC1D17 -1399
KIF20A -1419
UBA52 -1437
VPS4A -1442
BLOC1S6 -1527
HYOU1 -1539
IGHV3-13 -1600
GPS1 -1667
FNBP1 -1683
C2CD5 -1853
SEC23IP -1883
AP4S1 -1900
KIF4A -1930
IGLV3-25 -1935
ARFIP2 -2077
IGHA2 -2084
IGLV1-36 -2214
IGHV4-59 -2340
BLOC1S3 -2366
GCC1 -2396
UBB -2442
CHM -2462
HPX -2463
KIF26A -2475
BICD1 -2480
STAM -2492
SYTL1 -2519
EPGN -2690
M6PR -2706
COPS4 -2709
ZW10 -2813
EXOC5 -2814
MYO1C -2881
TRIP11 -2915
IGKV1-17 -2929
COG2 -2945
IGKV2-30 -2958
KIFC1 -2979
DENND4A -2989
IGLV1-40 -3024
RAB9A -3056
DTNBP1 -3111
MAN2A1 -3130
RAB27B -3133
STON2 -3139
SYS1 -3149
CNIH1 -3155
DENND2A -3181
USE1 -3189
KIF16B -3205
CD59 -3215
KIF15 -3250
KLC2 -3299
IGLV4-69 -3305
ARL1 -3337
BET1L -3403
RAB4A -3411
SSC5D -3539
IGHV1-46 -3558
IGHV3-11 -3626
AP2B1 -3690
RAB33A -3731
LNPEP -3755
RAB6B -3798
SH3D19 -3800
COG3 -3840
GOLGA4 -3948
VPS36 -3954
MIA3 -3981
KIF11 -4054
GJB6 -4155
GOLGB1 -4180
TXNDC5 -4205
PRKAB2 -4214
CHML -4221
IGHV2-70 -4223
HPS4 -4226
RABEP1 -4244
IGLC1 -4280
IGKV2-28 -4281
CTTN -4321
PAFAH1B3 -4377
IGKV1-12 -4392
SPARC -4397
IGLV1-47 -4485
HSP90B1 -4493
ARFRP1 -4510
SCARF1 -4517
SLC2A8 -4567
RAB9B -4668
IGHV3-30 -4685
BNIP1 -4852
CD4 -4882
IGHV4-39 -4884
DVL2 -4905
SEC22C -4952
IGKV1-33 -4953
TRIP10 -4971
IGKV3-20 -5082
HSP90AA1 -5083
DENND4C -5121
IGLC2 -5138
CALM1 -5150
DENND1B -5178
PLA2G6 -5218
IGHV3-7 -5228
IGKC -5232
IGHA1 -5247
KIFAP3 -5269
BET1 -5288
IGLV1-51 -5296
TBC1D15 -5322
COLEC12 -5383
COG1 -5406
GCC2 -5428
RINL -5487
COG6 -5508
IGHV1-2 -5526
SRC -5527
EXOC2 -5595
IGLV8-61 -5601
IGHV3-23 -5636
IGLV3-27 -5637
IGLC7 -5764
ANKRD28 -5772
IGHV3-48 -5881
CYTH3 -5975
ANK3 -5980
SBF1 -6038
YWHAQ -6039
GOSR1 -6194
MAN1A2 -6257
COPZ2 -6311
CNIH3 -6337
KIF26B -6414
KIF28P -6568
IGHV2-5 -6583
IGHV4-34 -6614
IGHV3-53 -6692
DENND5B -6724
AAK1 -6772
TMED10 -6868
ADRB2 -6879
IGLV7-46 -6955
NAA35 -7044
BLOC1S4 -7101
SEC22A -7145
TRAPPC2 -7210
VAMP2 -7244
KIF5A -7265
TBC1D10C -7271
IGKV4-1 -7302
KIF20B -7321
IGLV3-19 -7358
IGKV1-5 -7365
AP1M2 -7416
STX17 -7461
IGLV2-8 -7468
HSPH1 -7472
IGLV3-12 -7540
IGHV1-69 -7589
JCHAIN -7676
IGKV3-15 -7683
MYO6 -7690
AP1S2 -7941
RALA -7942
TRAPPC6A -8005
DYNLL2 -8015
CYTH1 -8122
COPS8 -8134
KIF21A -8147
IGLV3-1 -8150
IGLV3-21 -8327
BIN1 -8338
IGKV1-16 -8350
SCOC -8353
KIF2A -8455
VPS51 -8516
IGHV3-33 -8574
IGLV2-14 -8599
HIP1R -8643
SPTBN1 -8685
RINT1 -8687
RPS27A -8722
CD3D -8747
AKT3 -8761
IGLV2-18 -8778
KIF22 -8858
RHOBTB3 -8939
IGLV5-45 -8955
KIF3A -8957
RAB30 -8962
IGLV6-57 -8979
PACSIN1 -8985
LMAN1 -8999
CD3G -9125
OPTN -9165
HSPA8 -9166
NAA30 -9177
CHMP7 -9399
RAB39B -9422
IGKV3-11 -9443
DENND2D -9502
SPTAN1 -9516
TBC1D4 -9523
ALS2CL -9549
TPD52 -9559
SYNJ2 -9603
MAN1C1 -9615
LDLRAP1 -9809
KIF5C -9849
IL7R -9876


Generation of second messenger molecules

Generation of second messenger molecules
444
set Generation of second messenger molecules
setSize 38
pANOVA 1.37e-06
s.dist -0.453
p.adjustANOVA 2.92e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
TRBV12-3 -9724
CD247 -9497
LCK -9485
HLA-DQA2 -9407
TRAV19 -9396
CD3E -9378
TRAC -9330
ITK -9231
LAT -9159
CD3G -9125
HLA-DQB2 -9021
NCK1 -8821
CD3D -8747
TRBC1 -8666
ZAP70 -8662
EVL -8581
PLCG1 -8497
TRAV29DV5 -8326
TRAV8-4 -7607
HLA-DPB1 -7109

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TRBV12-3 -9724
CD247 -9497
LCK -9485
HLA-DQA2 -9407
TRAV19 -9396
CD3E -9378
TRAC -9330
ITK -9231
LAT -9159
CD3G -9125
HLA-DQB2 -9021
NCK1 -8821
CD3D -8747
TRBC1 -8666
ZAP70 -8662
EVL -8581
PLCG1 -8497
TRAV29DV5 -8326
TRAV8-4 -7607
HLA-DPB1 -7109
TRBV7-9 -6741
HLA-DRA -6613
GRAP2 -6236
HLA-DPA1 -5854
CD4 -4882
HLA-DQA1 -1465
HLA-DRB5 -1119
PAK3 -533
LCP2 514
CD101 551
HLA-DRB1 1353
HLA-DQB1 3660
PAK2 5789
ENAH 6964
VASP 9774
PLCG2 10376
PAK1 10704
WAS 11238


PD-1 signaling

PD-1 signaling
778
set PD-1 signaling
setSize 28
pANOVA 1.37e-06
s.dist -0.527
p.adjustANOVA 2.92e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
TRBV12-3 -9724
CD247 -9497
LCK -9485
HLA-DQA2 -9407
TRAV19 -9396
CD3E -9378
TRAC -9330
CD3G -9125
HLA-DQB2 -9021
CD3D -8747
TRBC1 -8666
TRAV29DV5 -8326
PDCD1 -7990
TRAV8-4 -7607
CD274 -7428
HLA-DPB1 -7109
TRBV7-9 -6741
HLA-DRA -6613
HLA-DPA1 -5854
CD4 -4882

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TRBV12-3 -9724
CD247 -9497
LCK -9485
HLA-DQA2 -9407
TRAV19 -9396
CD3E -9378
TRAC -9330
CD3G -9125
HLA-DQB2 -9021
CD3D -8747
TRBC1 -8666
TRAV29DV5 -8326
PDCD1 -7990
TRAV8-4 -7607
CD274 -7428
HLA-DPB1 -7109
TRBV7-9 -6741
HLA-DRA -6613
HLA-DPA1 -5854
CD4 -4882
HLA-DQA1 -1465
HLA-DRB5 -1119
HLA-DRB1 1353
PTPN11 2859
HLA-DQB1 3660
PDCD1LG2 4134
CSK 10310
PTPN6 11254


mRNA Splicing - Major Pathway

mRNA Splicing - Major Pathway
1336
set mRNA Splicing - Major Pathway
setSize 179
pANOVA 1.67e-06
s.dist -0.208
p.adjustANOVA 3.49e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
RBMX -9321
HSPA8 -9166
HNRNPA0 -9015
GCFC2 -8941
SNRPN -8838
SF3B3 -8790
WBP11 -8686
NUDT21 -8636
PRPF19 -8548
SNRNP40 -8492
NCBP2 -8212
POLR2D -8160
LSM5 -8094
SRSF5 -7996
SNU13 -7987
HNRNPR -7882
SRSF11 -7838
SRSF10 -7755
PPIH -7717
HNRNPA1 -7469

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RBMX -9321
HSPA8 -9166
HNRNPA0 -9015
GCFC2 -8941
SNRPN -8838
SF3B3 -8790
WBP11 -8686
NUDT21 -8636
PRPF19 -8548
SNRNP40 -8492
NCBP2 -8212
POLR2D -8160
LSM5 -8094
SRSF5 -7996
SNU13 -7987
HNRNPR -7882
SRSF11 -7838
SRSF10 -7755
PPIH -7717
HNRNPA1 -7469
CSTF1 -7377
HNRNPA3 -7261
PPIL1 -7166
PRPF6 -7127
SRSF6 -7099
RNPS1 -7032
SNRPE -6979
SF3A3 -6863
PLRG1 -6780
SNRPF -6725
SF3B1 -6469
PRPF8 -6374
RBM17 -6331
SNRNP200 -6070
ELAVL1 -5954
SF3A1 -5895
BCAS2 -5731
LSM4 -5680
DHX9 -5556
SRSF3 -5528
LSM7 -5504
PPWD1 -5498
SNRNP70 -5483
POLR2B -5111
SF3A2 -5104
SRSF2 -5095
PPIE -5064
SNRPA1 -4867
LSM8 -4763
SNRPD2 -4757
MTREX -4734
SRSF7 -4657
HNRNPH1 -4617
U2SURP -4531
DHX15 -4502
SNRPD3 -4404
PTBP1 -4302
CSTF2T -4089
CWC22 -4076
MAGOHB -4045
FIP1L1 -3955
POLR2K -3902
DDX5 -3820
PPIL4 -3815
SNRPD1 -3757
POLR2H -3611
CRNKL1 -3606
SNRPB -3546
ALYREF -3518
PRPF38A -3334
SRRT -3284
SRSF1 -3108
UPF3B -3065
RBM8A -2980
CHERP -2861
CSTF2 -2788
POLR2C -2566
PPIL3 -2544
HNRNPD -2497
SNRPB2 -2429
LSM2 -2392
DDX42 -2376
CPSF4 -2319
PQBP1 -2305
PCBP2 -2170
PRPF31 -2159
DNAJC8 -2118
SRRM1 -2111
MAGOH -1931
SLU7 -1726
POLR2I -1599
CCAR1 -1587
ISY1 -1477
DHX16 -1369
PRPF3 -1341
PUF60 -1289
HNRNPF -1277
SNRNP27 -1210
NCBP1 -1125
SF1 -1103
HNRNPUL1 -917
EIF4A3 -915
CWC27 -901
HNRNPU -781
PHF5A -696
SNRPC -613
XAB2 -562
YBX1 -423
PRPF40A -396
FUS -263
WDR33 -253
LSM3 21
TRA2B 372
CWC15 544
USP39 611
SF3B5 672
DDX46 825
U2AF2 883
SYF2 941
U2AF1L4 985
DHX38 1001
RBM22 1158
AQR 1282
CDC5L 1283
SNW1 1506
RBM5 1791
SMNDC1 1892
PAPOLA 2096
WBP4 2342
PCF11 2498
PABPN1 2573
SF3B2 2587
HNRNPK 2644
SF3B6 2791
PPIL6 2992
PRPF4 3084
SRRM2 3184
HNRNPM 3201
HNRNPC 3313
CDC40 3360
SNRPA 3417
POLR2L 3450
CWC25 3513
CLP1 3627
TFIP11 3706
U2AF1 3739
SNRPG 3835
SF3B4 3986
GPKOW 4101
PRCC 4237
SART1 4376
SYMPK 4502
CTNNBL1 4575
CPSF2 4583
CPSF1 4828
CPSF7 4872
PCBP1 5106
POLR2E 5238
GTF2F2 5263
LSM6 5419
BUD31 5489
GTF2F1 5494
POLR2G 5695
POLR2F 5738
HNRNPL 5742
DDX23 6081
CSTF3 6324
HNRNPA2B1 6339
POLR2A 6387
TXNL4A 6590
CPSF3 6658
HNRNPH2 6735
SUGP1 6788
SRSF4 7078
CASC3 7085
POLR2J 7983
EFTUD2 8476
CD2BP2 9074
SRSF9 9246


tRNA processing in the nucleus

tRNA processing in the nucleus
1361
set tRNA processing in the nucleus
setSize 59
pANOVA 1.89e-06
s.dist -0.359
p.adjustANOVA 3.9e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
NDC1 -9817
NUP35 -9626
RPP40 -9619
NUP88 -9430
NUP107 -8801
SEH1L -8792
NUP160 -8699
TSEN54 -8093
NUP43 -7792
NUP155 -7633
RPP25 -7624
RAN -7577
NUP188 -7295
RPP30 -7173
TSEN15 -7067
TSEN2 -7057
NUP205 -7051
RPP38 -6534
XPOT -6407
POM121C -6074

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NDC1 -9817
NUP35 -9626
RPP40 -9619
NUP88 -9430
NUP107 -8801
SEH1L -8792
NUP160 -8699
TSEN54 -8093
NUP43 -7792
NUP155 -7633
RPP25 -7624
RAN -7577
NUP188 -7295
RPP30 -7173
TSEN15 -7067
TSEN2 -7057
NUP205 -7051
RPP38 -6534
XPOT -6407
POM121C -6074
DDX1 -5751
NUP133 -5674
FAM98B -5439
NUP54 -5340
POP5 -5173
C2orf49 -4992
POP1 -4584
NUP153 -4433
NUP210 -4373
TPR -4127
RTRAF -3817
ELAC2 -3686
NUP93 -3163
RANBP2 -3109
CSTF2 -2788
NUP42 -2718
TRNT1 -2576
RPP14 -2433
CPSF4 -2319
POM121 -2295
NUP85 -1717
NUP37 -1424
NUP50 -1242
POP4 -441
RPP21 -200
NUP98 175
NUP62 395
AAAS 627
RTCB 848
POP7 963
CLP1 3627
CPSF1 4828
RAE1 5040
SEC13 6793
TSEN34 7554
NUP58 7628
ZBTB8OS 9012
NUP214 10124
RPPH1 11164


ER to Golgi Anterograde Transport

ER to Golgi Anterograde Transport
326
set ER to Golgi Anterograde Transport
setSize 129
pANOVA 2.04e-06
s.dist 0.242
p.adjustANOVA 4.16e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
SERPINA1 11685
F5 11617
COG7 11491
COPG1 11346
GORASP1 10996
CTSZ 10773
CD55 10741
DCTN2 10458
ARF1 10356
SEC24D 10340
PREB 10297
COL7A1 10174
ACTR1A 10067
TGFA 9932
RAB1A 9919
NSF 9858
COPA 9848
TMED9 9614
ARF5 9584
KDELR1 9578

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SERPINA1 11685
F5 11617
COG7 11491
COPG1 11346
GORASP1 10996
CTSZ 10773
CD55 10741
DCTN2 10458
ARF1 10356
SEC24D 10340
PREB 10297
COL7A1 10174
ACTR1A 10067
TGFA 9932
RAB1A 9919
NSF 9858
COPA 9848
TMED9 9614
ARF5 9584
KDELR1 9578
CTSC 9524
DCTN4 9451
RAB1B 9447
DCTN6 9325
SEC16B 9315
DCTN1 9214
ARF4 9156
COG4 9044
LMAN2 8931
TRAPPC1 8880
COPE 8787
NAPG 8778
COPG2 8671
ARF3 8602
CAPZB 8593
NAPA 8477
GOLGA2 8366
DYNC1LI2 8092
STX5 8070
CAPZA1 8032
CAPZA2 7999
SCFD1 7929
PPP6R1 7922
DCTN3 7885
DYNC1LI1 7881
TFG 7873
SEC16A 7812
CSNK1D 7458
SEC24C 7065
TRAPPC3 7024
SEC24A 6928
SEC13 6793
ARFGAP2 6724
COPB2 6710
YKT6 6467
CNIH2 6334
GBF1 6282
COPB1 6181
ARFGAP1 6078
DYNC1I2 5729
SPTBN5 5455
KDELR2 4945
F8 4773
TRAPPC5 4592
SAR1B 4545
SEC24B 4410
MIA2 4301
ACTR10 4228
TMEM115 3887
TMED3 3759
NAPB 3641
SPTB 3448
ARFGAP3 3442
DYNLL1 3185
COPZ1 2925
GOSR2 2697
SEC22B 2167
TRAPPC2L 2058
SEC31A 2016
SEC23A 1838
TBC1D20 1725
ARCN1 1716
LMAN2L 1671
SPTA1 1589
TRAPPC9 1554
DYNC1I1 1191
TMED2 965
AREG 932
KDELR3 810
ANK1 741
COG5 706
MCFD2 660
SPTBN2 565
TRAPPC10 441
USO1 -110
PPP6R3 -249
TRAPPC6B -434
DCTN5 -898
DYNC1H1 -1040
PPP6C -1168
TRAPPC4 -1304
TMED7 -1318
COG8 -1340
SEC23IP -1883
COG2 -2945
CNIH1 -3155
CD59 -3215
BET1L -3403
COG3 -3840
MIA3 -3981
GOLGB1 -4180
SEC22C -4952
BET1 -5288
COG1 -5406
COG6 -5508
ANKRD28 -5772
ANK3 -5980
GOSR1 -6194
COPZ2 -6311
CNIH3 -6337
TMED10 -6868
SEC22A -7145
TRAPPC2 -7210
STX17 -7461
TRAPPC6A -8005
DYNLL2 -8015
SPTBN1 -8685
LMAN1 -8999
SPTAN1 -9516


Initial triggering of complement

Initial triggering of complement
532
set Initial triggering of complement
setSize 78
pANOVA 2.23e-06
s.dist -0.31
p.adjustANOVA 4.48e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
IGKV3-11 -9443
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
GZMM -7924
IGKV3-15 -7683
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
IGLV7-46 -6955
IGHV3-53 -6692
IGHV4-34 -6614

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IGKV3-11 -9443
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
GZMM -7924
IGKV3-15 -7683
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
IGLV7-46 -6955
IGHV3-53 -6692
IGHV4-34 -6614
IGHV2-5 -6583
IGHV3-48 -5881
IGLC7 -5764
IGLV3-27 -5637
IGHV3-23 -5636
IGLV8-61 -5601
IGHV1-2 -5526
IGLV1-51 -5296
IGKC -5232
IGHV3-7 -5228
IGLC2 -5138
IGKV3-20 -5082
IGKV1-33 -4953
IGHV4-39 -4884
IGHV3-30 -4685
IGLV1-47 -4485
IGKV1-12 -4392
IGKV2-28 -4281
IGLC1 -4280
IGHV2-70 -4223
IGHG3 -4128
IGHV3-11 -3626
IGHV1-46 -3558
IGLV4-69 -3305
IGHG2 -3113
IGLV1-40 -3024
IGKV2-30 -2958
IGKV1-17 -2929
IGHV4-59 -2340
IGLV1-36 -2214
IGLV3-25 -1935
IGHV3-13 -1600
IGHG1 -1504
IGLV1-44 -1090
IGHG4 -760
IGKV2D-28 -728
IGLC3 -403
MASP2 -330
IGKV3D-20 -305
IGLV10-54 -276
IGLV2-23 1244
C4A 1786
C3 1898
CFD 2249
C1S 2813
IGKV5-2 3051
IGLV2-11 3601
IGKV1D-39 3771
C1R 4413
C4B 5483
IGLV7-43 7123
FCN1 9194
IGKV1-39 9771
CFB 11024
C1QA 11453
C2 11573
C1QC 11693
C1QB 11723


mRNA Splicing

mRNA Splicing
1335
set mRNA Splicing
setSize 187
pANOVA 2.51e-06
s.dist -0.2
p.adjustANOVA 4.96e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
RBMX -9321
HSPA8 -9166
HNRNPA0 -9015
GCFC2 -8941
SNRPN -8838
SF3B3 -8790
WBP11 -8686
NUDT21 -8636
PRPF19 -8548
SNRNP40 -8492
NCBP2 -8212
POLR2D -8160
LSM5 -8094
SRSF5 -7996
SNU13 -7987
HNRNPR -7882
SRSF11 -7838
SRSF10 -7755
PPIH -7717
HNRNPA1 -7469

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RBMX -9321
HSPA8 -9166
HNRNPA0 -9015
GCFC2 -8941
SNRPN -8838
SF3B3 -8790
WBP11 -8686
NUDT21 -8636
PRPF19 -8548
SNRNP40 -8492
NCBP2 -8212
POLR2D -8160
LSM5 -8094
SRSF5 -7996
SNU13 -7987
HNRNPR -7882
SRSF11 -7838
SRSF10 -7755
PPIH -7717
HNRNPA1 -7469
CSTF1 -7377
HNRNPA3 -7261
PPIL1 -7166
PRPF6 -7127
SRSF6 -7099
RNPS1 -7032
SNRPE -6979
SF3A3 -6863
PLRG1 -6780
SNRPF -6725
SF3B1 -6469
PRPF8 -6374
RBM17 -6331
PDCD7 -6173
SNRNP200 -6070
ELAVL1 -5954
SF3A1 -5895
BCAS2 -5731
LSM4 -5680
SNRNP48 -5596
DHX9 -5556
SRSF3 -5528
LSM7 -5504
PPWD1 -5498
SNRNP70 -5483
POLR2B -5111
SF3A2 -5104
SRSF2 -5095
PPIE -5064
SNRPA1 -4867
LSM8 -4763
SNRPD2 -4757
MTREX -4734
SRSF7 -4657
HNRNPH1 -4617
U2SURP -4531
DHX15 -4502
SNRPD3 -4404
PTBP1 -4302
CSTF2T -4089
CWC22 -4076
MAGOHB -4045
FIP1L1 -3955
POLR2K -3902
DDX5 -3820
PPIL4 -3815
SNRPD1 -3757
POLR2H -3611
CRNKL1 -3606
SNRPB -3546
ALYREF -3518
PRPF38A -3334
SRRT -3284
SRSF1 -3108
UPF3B -3065
RBM8A -2980
CHERP -2861
CSTF2 -2788
POLR2C -2566
PPIL3 -2544
HNRNPD -2497
SNRPB2 -2429
LSM2 -2392
DDX42 -2376
CPSF4 -2319
PQBP1 -2305
PCBP2 -2170
PRPF31 -2159
DNAJC8 -2118
SRRM1 -2111
MAGOH -1931
SLU7 -1726
POLR2I -1599
CCAR1 -1587
RNPC3 -1544
ZCRB1 -1532
ISY1 -1477
DHX16 -1369
PRPF3 -1341
PUF60 -1289
HNRNPF -1277
SNRNP27 -1210
NCBP1 -1125
SF1 -1103
HNRNPUL1 -917
EIF4A3 -915
CWC27 -901
HNRNPU -781
PHF5A -696
SNRPC -613
XAB2 -562
YBX1 -423
PRPF40A -396
FUS -263
WDR33 -253
LSM3 21
TRA2B 372
CWC15 544
USP39 611
SNRNP25 671
SF3B5 672
DDX46 825
U2AF2 883
SYF2 941
U2AF1L4 985
DHX38 1001
RBM22 1158
AQR 1282
CDC5L 1283
SNW1 1506
ZRSR2 1562
RBM5 1791
SMNDC1 1892
PAPOLA 2096
WBP4 2342
PCF11 2498
PABPN1 2573
SF3B2 2587
HNRNPK 2644
SF3B6 2791
PPIL6 2992
PRPF4 3084
SRRM2 3184
HNRNPM 3201
HNRNPC 3313
CDC40 3360
SNRPA 3417
POLR2L 3450
CWC25 3513
CLP1 3627
TFIP11 3706
U2AF1 3739
SNRPG 3835
SF3B4 3986
GPKOW 4101
PRCC 4237
SART1 4376
SYMPK 4502
CTNNBL1 4575
CPSF2 4583
CPSF1 4828
CPSF7 4872
PCBP1 5106
POLR2E 5238
GTF2F2 5263
LSM6 5419
BUD31 5489
GTF2F1 5494
POLR2G 5695
POLR2F 5738
HNRNPL 5742
DDX23 6081
CSTF3 6324
HNRNPA2B1 6339
POLR2A 6387
TXNL4A 6590
CPSF3 6658
HNRNPH2 6735
SUGP1 6788
SRSF4 7078
CASC3 7085
POLR2J 7983
SNRNP35 8105
EFTUD2 8476
CD2BP2 9074
SRSF9 9246
ZMAT5 10301


Mitotic Prometaphase

Mitotic Prometaphase
677
set Mitotic Prometaphase
setSize 184
pANOVA 2.79e-06
s.dist -0.2
p.adjustANOVA 5.44e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
CEP76 -9542
TUBB4A -9524
BUB3 -9475
SPDL1 -9307
CENPH -9233
OFD1 -9086
MIS12 -9038
CEP78 -8971
NUP107 -8801
SEH1L -8792
CEP72 -8753
ITGB3BP -8742
NUP160 -8699
HAUS3 -8547
CEP57 -8544
MAD2L1 -8491
TUBG2 -8465
KIF2A -8455
CEP70 -8423
ODF2 -8342

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CEP76 -9542
TUBB4A -9524
BUB3 -9475
SPDL1 -9307
CENPH -9233
OFD1 -9086
MIS12 -9038
CEP78 -8971
NUP107 -8801
SEH1L -8792
CEP72 -8753
ITGB3BP -8742
NUP160 -8699
HAUS3 -8547
CEP57 -8544
MAD2L1 -8491
TUBG2 -8465
KIF2A -8455
CEP70 -8423
ODF2 -8342
CENPM -8299
RPS27 -8260
RANGAP1 -8224
DYNLL2 -8015
NUP43 -7792
CENPQ -7689
PPP2R5C -7679
SFI1 -7605
CSNK1E -7527
HAUS6 -7511
MZT2A -7471
NINL -7404
SMC2 -7215
HAUS5 -7120
PLK4 -7001
CENPJ -6905
MZT1 -6883
PRKAR2B -6807
SGO2 -6783
STAG1 -6554
NDC80 -6377
PPP2R5E -6283
RAD21 -6258
PCNT -6252
CEP290 -6203
CENPC -6141
ZWINT -6019
BUB1B -5801
BUB1 -5773
CENPT -5770
SMC3 -5758
NUP133 -5674
CDK1 -5568
TUBGCP6 -5515
CENPL -5433
SMC4 -5416
TUBB -5289
AHCTF1 -5169
NEK7 -5144
EML4 -5100
HSP90AA1 -5083
ZWILCH -5036
CDK5RAP2 -5035
TUBGCP5 -4715
CLASP2 -4711
CENPK -4642
PDS5A -4597
MZT2B -4548
KNTC1 -4400
CENPN -4391
ALMS1 -4279
NUF2 -4277
NUDC -4267
NCAPH -4213
XPO1 -4204
CEP131 -4139
AKAP9 -3928
CDCA5 -3870
SKA2 -3420
DSN1 -3386
RANBP2 -3109
PPP2R1B -2904
TUBGCP4 -2883
ZW10 -2813
CEP41 -2740
CENPU -2720
CDCA8 -2626
CENPA -2615
CCNB1 -2524
NCAPG -2509
STAG2 -2436
NME7 -2347
CETN2 -2342
CEP135 -2331
PDS5B -2230
CEP250 -2187
CENPF -2144
CDC20 -1938
NUP85 -1717
HAUS7 -1485
NUP37 -1424
WAPL -1381
PCM1 -1329
NEDD1 -1240
CNTRL -1047
DYNC1H1 -1040
CKAP5 -824
HAUS8 -804
SMC1A -662
INCENP -614
BIRC5 -333
NUMA1 -102
PMF1 52
KIF18A 102
SPC24 111
HAUS2 112
CCP110 126
NUP98 175
NEK2 345
AURKB 781
NEK9 870
HAUS1 943
TUBG1 982
NCAPD2 1097
KIF2C 1104
DYNC1I1 1191
CENPI 1203
CEP192 1304
CLASP1 1310
CENPE 1952
KNL1 2231
PPP2R5D 2555
SSNA1 2600
PPP1CC 2943
PLK1 2972
CENPP 3032
SKA1 3064
DYNLL1 3185
MAD1L1 3435
CEP164 3597
SGO1 3635
MAPRE1 3656
PAFAH1B1 3738
CCNB2 3892
TUBA4A 3909
ERCC6L 4040
CSNK2A2 4323
PPP2R1A 4593
NDE1 4671
RCC2 4844
PPP2CA 4882
PPP2CB 5377
DYNC1I2 5729
CENPO 5838
TAOK1 6148
CSNK2B 6563
CEP63 6566
TUBB4B 6583
SEC13 6793
CEP152 7449
CSNK1D 7458
PPP2R5A 7512
TUBA1A 7690
TUBGCP2 7795
DYNC1LI1 7881
DCTN3 7885
CSNK2A1 7984
DYNC1LI2 8092
NEK6 8427
YWHAE 8584
NSL1 8609
SDCCAG8 8730
B9D2 8773
TUBGCP3 8804
DCTN1 9214
NDEL1 9493
HDAC8 9800
YWHAG 9892
ACTR1A 10067
DCTN2 10458
PPP2R5B 10579
CLIP1 10667
HAUS4 11267
PRKACA 11578


Interactions of Vpr with host cellular proteins

Interactions of Vpr with host cellular proteins
546
set Interactions of Vpr with host cellular proteins
setSize 37
pANOVA 3.55e-06
s.dist -0.44
p.adjustANOVA 6.81e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
NDC1 -9817
NUP35 -9626
NUP88 -9430
PSIP1 -8864
NUP107 -8801
SEH1L -8792
NUP160 -8699
HMGA1 -8468
NUP43 -7792
NUP155 -7633
SLC25A4 -7576
NUP188 -7295
NUP205 -7051
POM121C -6074
NUP133 -5674
SLC25A6 -5581
NUP54 -5340
NUP153 -4433
NUP210 -4373
BANF1 -4324

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NDC1 -9817
NUP35 -9626
NUP88 -9430
PSIP1 -8864
NUP107 -8801
SEH1L -8792
NUP160 -8699
HMGA1 -8468
NUP43 -7792
NUP155 -7633
SLC25A4 -7576
NUP188 -7295
NUP205 -7051
POM121C -6074
NUP133 -5674
SLC25A6 -5581
NUP54 -5340
NUP153 -4433
NUP210 -4373
BANF1 -4324
KPNA1 -4278
TPR -4127
NUP93 -3163
RANBP2 -3109
NUP42 -2718
SLC25A5 -2499
POM121 -2295
NUP85 -1717
NUP37 -1424
NUP50 -1242
NUP98 175
NUP62 395
AAAS 627
RAE1 5040
SEC13 6793
NUP58 7628
NUP214 10124


FCGR3A-mediated IL10 synthesis

FCGR3A-mediated IL10 synthesis
362
set FCGR3A-mediated IL10 synthesis
setSize 99
pANOVA 3.84e-06
s.dist -0.269
p.adjustANOVA 7.27e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
PRKACB -9741
CD247 -9497
IGKV3-11 -9443
CD3G -9125
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
PLCG1 -8497
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
PRKX -7747
IGKV3-15 -7683
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PRKACB -9741
CD247 -9497
IGKV3-11 -9443
CD3G -9125
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
PLCG1 -8497
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
PRKX -7747
IGKV3-15 -7683
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
IGLV7-46 -6955
PRKAR2B -6807
IGHV3-53 -6692
FYN -6619
IGHV4-34 -6614
IGHV2-5 -6583
IGHV3-48 -5881
IGLC7 -5764
ITPR3 -5727
YES1 -5662
IGLV3-27 -5637
IGHV3-23 -5636
IGLV8-61 -5601
SRC -5527
IGHV1-2 -5526
IGLV1-51 -5296
IGKC -5232
IGHV3-7 -5228
CALM1 -5150
IGLC2 -5138
IGKV3-20 -5082
IGKV1-33 -4953
IGHV4-39 -4884
IGHV3-30 -4685
IGLV1-47 -4485
IGKV1-12 -4392
IGKV2-28 -4281
IGLC1 -4280
IGHV2-70 -4223
IGHG3 -4128
ITPR1 -3809
CREB1 -3751
IGHV3-11 -3626
IGHV1-46 -3558
ADCY9 -3346
IGLV4-69 -3305
IGHG2 -3113
IGLV1-40 -3024
ADCY6 -3011
IGKV2-30 -2958
IGKV1-17 -2929
IGHV4-59 -2340
IGLV1-36 -2214
IGLV3-25 -1935
ADCY5 -1841
IGHV3-13 -1600
IGHG1 -1504
IGLV1-44 -1090
IGHG4 -760
IGKV2D-28 -728
IGLC3 -403
IGKV3D-20 -305
IGLV10-54 -276
IGLV2-23 1244
PRKAR1B 2590
PRKAR2A 2979
IGKV5-2 3051
ADCY2 3583
IGLV2-11 3601
IGKV1D-39 3771
AHCYL1 4099
ITPR2 6136
IGLV7-43 7123
ADCY7 8054
ADCY4 8875
IGKV1-39 9771
PRKAR1A 9782
SYK 10086
IL10 10154
FCGR2A 10355
PLCG2 10376
LYN 10893
FCGR3A 11056
FCGR1A 11256
HCK 11416
PRKACA 11578
FGR 11610
ADCY3 11662


Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
519
set Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
setSize 182
pANOVA 4.09e-06
s.dist -0.198
p.adjustANOVA 7.55e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
CD1C -9851
SH2D1A -9847
KLRB1 -9834
SIGLEC6 -9821
CD96 -9792
TRBV12-3 -9724
SH2D1B -9688
CD200R1 -9627
ICAM2 -9623
KLRF1 -9605
CD247 -9497
IGKV3-11 -9443
NCR1 -9406
TRAV19 -9396
CD40LG -9383
CD3E -9378
TRAC -9330
CD34 -9323
CD3G -9125
CD160 -9124

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CD1C -9851
SH2D1A -9847
KLRB1 -9834
SIGLEC6 -9821
CD96 -9792
TRBV12-3 -9724
SH2D1B -9688
CD200R1 -9627
ICAM2 -9623
KLRF1 -9605
CD247 -9497
IGKV3-11 -9443
NCR1 -9406
TRAV19 -9396
CD40LG -9383
CD3E -9378
TRAC -9330
CD34 -9323
CD3G -9125
CD160 -9124
IGLV6-57 -8979
IGLV5-45 -8955
SLAMF6 -8918
IGLV2-18 -8778
CD3D -8747
KLRC1 -8730
CLEC2D -8716
TRBC1 -8666
IGLV2-14 -8599
IGHV3-33 -8574
IGKV1-16 -8350
IGLV3-21 -8327
TRAV29DV5 -8326
IGLV3-1 -8150
CRTAM -8148
NCR3LG1 -8113
ITGA4 -7966
PIANP -7863
ITGB7 -7855
CD226 -7762
KLRD1 -7719
IGKV3-15 -7683
KLRK1 -7644
TRAV8-4 -7607
IGHV1-69 -7589
IGLV3-12 -7540
CD8A -7501
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
B2M -7346
IGKV4-1 -7302
IGLV7-46 -6955
KLRG1 -6948
TRBV7-9 -6741
CD22 -6705
IGHV3-53 -6692
IGHV4-34 -6614
IGHV2-5 -6583
SLAMF7 -6215
CLEC2B -6125
IGHV3-48 -5881
IGLC7 -5764
IGLV3-27 -5637
IGHV3-23 -5636
IGLV8-61 -5601
CD8B -5592
IGHV1-2 -5526
HLA-A -5456
COLEC12 -5383
IGLV1-51 -5296
IGKC -5232
IGHV3-7 -5228
IGLC2 -5138
IGKV3-20 -5082
SIGLEC8 -5019
IGKV1-33 -4953
IGHV4-39 -4884
CD81 -4851
ITGB1 -4850
IGHV3-30 -4685
IGLV1-47 -4485
KIR3DL2 -4472
IGKV1-12 -4392
CD1A -4372
IGKV2-28 -4281
IGLC1 -4280
IGHV2-70 -4223
IFITM1 -4191
NCR3 -4141
CD19 -3919
IGHV3-11 -3626
IGHV1-46 -3558
PILRB -3453
IGLV4-69 -3305
HLA-G -3238
IGLV1-40 -3024
LILRA4 -3023
IGKV2-30 -2958
IGKV1-17 -2929
SIGLEC1 -2907
CDH1 -2771
HLA-E -2458
IGHV4-59 -2340
HLA-F -2235
IGLV1-36 -2214
IGLV3-25 -1935
IGHV3-13 -1600
NPDC1 -1573
LAIR2 -1555
KIR2DL1 -1395
HLA-H -1311
IGLV1-44 -1090
MICA -759
IGKV2D-28 -728
IGLC3 -403
IGKV3D-20 -305
IGLV10-54 -276
CD40 394
CD200 463
ULBP3 517
KIR3DL1 521
TREML1 901
IGLV2-23 1244
HCST 1343
FCGR2B 1390
C3 1898
MADCAM1 2244
HLA-B 2308
ITGAL 2879
IGKV5-2 3051
HLA-C 3114
IGLV2-11 3601
IGKV1D-39 3771
CD300LB 3957
CD99 4846
ICAM1 4889
ICAM3 5285
CD300LD 5392
SIGLEC5 6250
SIGLEC11 6390
IGLV7-43 7123
TREM1 7737
CD300LF 8051
CD1D 8207
TREML2 8674
SELL 8826
KIR2DL4 9236
SIGLEC12 9334
CD33 9340
KIR2DL3 9401
MICB 9553
IGKV1-39 9771
ICAM4 9941
JAML 10470
LILRB3 10546
PILRA 10610
CD300A 10650
TYROBP 10755
LILRA2 10790
SIGLEC7 10875
ITGB2 10970
FCGR3A 11056
NECTIN2 11224
FCGR1A 11256
LILRA1 11264
TREML4 11394
CD300E 11454
LAIR1 11472
SIGLEC9 11493
ICAM5 11496
PVR 11541
CD300C 11546
CLEC4G 11570
LILRB1 11607
LILRA5 11613
LILRB5 11651
LILRB4 11658
LILRA6 11705
OSCAR 11726
SIGLEC10 11729
LILRB2 11743


Post-translational protein phosphorylation

Post-translational protein phosphorylation
841
set Post-translational protein phosphorylation
setSize 70
pANOVA 4.1e-06
s.dist 0.318
p.adjustANOVA 7.55e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
FAM20A 11746
SERPINA1 11685
LGALS1 11621
F5 11617
LAMC1 11585
QSOX1 11547
PCSK9 11538
TIMP1 11482
FSTL3 11400
LAMB1 11317
VCAN 11287
FAM20C 11139
APLP2 11071
IGFBP7 10909
TMEM132A 10607
NUCB1 10433
GAS6 10432
APOA2 10312
PNPLA2 10177
CKAP4 10088

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FAM20A 11746
SERPINA1 11685
LGALS1 11621
F5 11617
LAMC1 11585
QSOX1 11547
PCSK9 11538
TIMP1 11482
FSTL3 11400
LAMB1 11317
VCAN 11287
FAM20C 11139
APLP2 11071
IGFBP7 10909
TMEM132A 10607
NUCB1 10433
GAS6 10432
APOA2 10312
PNPLA2 10177
CKAP4 10088
TGOLN2 9729
MELTF 9482
ALB 9450
P4HB 9433
ADAM10 9130
SERPIND1 8628
MBTPS1 8506
CP 8474
CALU 8310
DNAJC3 8291
ITIH2 8063
PROC 7786
ANO8 6828
SHISA5 6722
FUCA2 6509
SERPINA10 6256
PRKCSH 5698
MSLN 5574
TF 3776
CST3 3572
APP 3315
TNC 3001
ENAM 2889
LAMB2 2581
C3 1898
C4A 1786
APOL1 1736
PDIA6 1471
FGF23 1439
APOE 1230
IGFBP4 1179
SDC2 231
KTN1 -374
GOLM1 -1349
FN1 -1748
FBN1 -2384
FSTL1 -3115
LTBP1 -3123
MFGE8 -3307
MEN1 -3826
MIA3 -3981
HSP90B1 -4493
CSF1 -5020
RCN1 -6230
MXRA8 -6680
BMP4 -8222
WFS1 -8508
PRSS23 -8529
MGAT4A -9187
IGFBP3 -9434


Interactions of Rev with host cellular proteins

Interactions of Rev with host cellular proteins
545
set Interactions of Rev with host cellular proteins
setSize 37
pANOVA 4.77e-06
s.dist -0.435
p.adjustANOVA 8.66e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
NPM1 -9836
NDC1 -9817
NUP35 -9626
NUP88 -9430
NUP107 -8801
SEH1L -8792
NUP160 -8699
RANGAP1 -8224
NUP43 -7792
NUP155 -7633
RAN -7577
NUP188 -7295
NUP205 -7051
RANBP1 -6221
POM121C -6074
NUP133 -5674
NUP54 -5340
NUP153 -4433
NUP210 -4373
XPO1 -4204

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NPM1 -9836
NDC1 -9817
NUP35 -9626
NUP88 -9430
NUP107 -8801
SEH1L -8792
NUP160 -8699
RANGAP1 -8224
NUP43 -7792
NUP155 -7633
RAN -7577
NUP188 -7295
NUP205 -7051
RANBP1 -6221
POM121C -6074
NUP133 -5674
NUP54 -5340
NUP153 -4433
NUP210 -4373
XPO1 -4204
TPR -4127
NUP93 -3163
RANBP2 -3109
RCC1 -3085
NUP42 -2718
POM121 -2295
NUP85 -1717
NUP37 -1424
NUP50 -1242
KPNB1 -109
NUP98 175
NUP62 395
AAAS 627
RAE1 5040
SEC13 6793
NUP58 7628
NUP214 10124


S Phase

S Phase
1018
set S Phase
setSize 160
pANOVA 5.65e-06
s.dist -0.208
p.adjustANOVA 0.000101



Top enriched genes

Top 20 genes
GeneID Gene Rank
MCM3 -9769
POLD2 -9742
RBL2 -9700
POLA1 -9660
RPA1 -9657
CDC25B -9481
TFDP2 -9444
MYC -9418
ANAPC1 -9394
MCM6 -9297
POLE3 -8924
CUL1 -8878
AKT3 -8761
RPS27A -8722
RFC3 -8694
LIG1 -8618
CDK4 -8539
PRIM1 -8268
GINS4 -8200
ORC2 -8097

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MCM3 -9769
POLD2 -9742
RBL2 -9700
POLA1 -9660
RPA1 -9657
CDC25B -9481
TFDP2 -9444
MYC -9418
ANAPC1 -9394
MCM6 -9297
POLE3 -8924
CUL1 -8878
AKT3 -8761
RPS27A -8722
RFC3 -8694
LIG1 -8618
CDK4 -8539
PRIM1 -8268
GINS4 -8200
ORC2 -8097
ORC5 -8089
CDC23 -8076
RPA3 -8069
LIN9 -8001
RFC4 -7736
MCM7 -7720
MCM4 -7627
PSMB9 -7625
ORC3 -7568
MCM2 -7557
CDKN1B -7508
ANAPC16 -7186
FEN1 -7122
PCNA -6841
POLE2 -6659
STAG1 -6554
ESCO1 -6521
PSME1 -6399
PSMA5 -6362
RAD21 -6258
POLA2 -6222
MCM8 -6138
PSMC5 -5909
SKP1 -5791
SMC3 -5758
ORC4 -5692
PRIM2 -5653
MNAT1 -5650
CDC45 -5643
RFC1 -5493
LIN52 -5480
CDC6 -5479
E2F5 -5304
ORC1 -5158
WEE1 -4746
RBBP4 -4658
RPA2 -4620
PDS5A -4597
PSMD10 -4578
MAX -4483
PSMA3 -4338
CDT1 -4032
DNA2 -4017
GINS3 -3998
RFC5 -3986
ANAPC5 -3910
CDCA5 -3870
LIN54 -3805
CCND1 -3717
CDK2 -3694
CKS1B -3620
PSME2 -3570
GINS2 -3279
CCNE1 -2791
CDC27 -2558
CDC25A -2547
UBB -2442
STAG2 -2436
CCNA1 -2231
PDS5B -2230
ANAPC2 -2172
UBE2C -2114
ESCO2 -2104
PSMA2 -2032
PSMB1 -1960
CCNA2 -1727
CDC16 -1623
POLE -1479
UBA52 -1437
WAPL -1381
POLE4 -1186
PSME4 -1087
GINS1 -976
CABLES1 -831
SMC1A -662
SKP2 -520
PSMB10 -372
PSMA4 -118
E2F1 -108
CDC26 6
ANAPC10 141
PSMD14 225
UBE2E1 291
POLD1 646
ANAPC4 875
PSMF1 1056
MCM5 1277
PSMC4 1389
PSMD7 1547
FZR1 1793
PSMC3 2182
UBE2S 2306
GSK3B 2520
ANAPC7 2814
CDKN1A 3132
PSMA1 3451
PSMC6 3483
RBX1 3691
CCNE2 3704
PSMB4 3707
PSMD13 3770
PSMD3 4177
PSMA6 4263
TFDP1 4357
PSMC2 4457
ANAPC11 4464
PSMB2 4680
RFC2 4835
UBC 4874
CDK7 4908
LIN37 5346
AKT2 5390
PSMB8 5433
E2F4 5439
PSMD8 5474
PSMD2 5544
PSMD12 5714
PSMC1 5778
PSMD5 6029
AKT1 6133
PSMD1 6354
PSME3 6605
PSMD11 7057
CCNH 7145
SEM1 7739
PSMB7 7941
ORC6 8542
PSMB5 8625
PSMA7 8719
PSMD6 8745
PTK6 8980
PSMD9 9005
UBE2D1 9204
PSMB6 9262
RB1 9765
PSMB3 9902
ANAPC15 9931
PSMD4 10295
POLD4 10344
POLD3 11274


Mitochondrial translation elongation

Mitochondrial translation elongation
669
set Mitochondrial translation elongation
setSize 91
pANOVA 6.17e-06
s.dist -0.274
p.adjustANOVA 0.000109



Top enriched genes

Top 20 genes
GeneID Gene Rank
GFM1 -9259
MRPS30 -9238
MRPS6 -9227
MRPS33 -8868
MRPL50 -8779
MRPS18B -8387
MRPS27 -8372
MRPL17 -7946
MRPS25 -7801
MRPL46 -7776
MRPS17 -7515
MRPL49 -7488
MRPL24 -7374
MRPL48 -7205
MRPL3 -6766
MRPL38 -6536
MT-RNR1 -6484
MRPL1 -6477
MRPS9 -6468
MRPS14 -6456

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GFM1 -9259
MRPS30 -9238
MRPS6 -9227
MRPS33 -8868
MRPL50 -8779
MRPS18B -8387
MRPS27 -8372
MRPL17 -7946
MRPS25 -7801
MRPL46 -7776
MRPS17 -7515
MRPL49 -7488
MRPL24 -7374
MRPL48 -7205
MRPL3 -6766
MRPL38 -6536
MT-RNR1 -6484
MRPL1 -6477
MRPS9 -6468
MRPS14 -6456
MRPL35 -6300
MRPL45 -6248
MRPS2 -6123
MRPL9 -5999
DAP3 -5995
MRPL32 -5558
MRPL42 -5308
MRPL54 -5211
MRPL11 -5071
MRPS7 -5007
PTCD3 -4586
MRPL14 -4414
MRPL39 -4366
MRPS12 -4356
MRPL30 -4147
MRPS31 -4116
MRPL19 -4110
MRPS28 -3921
MRPL34 -3892
MRPL43 -3700
MRPL55 -3601
TSFM -3472
MRPL12 -3417
MRPL15 -3362
MRPS10 -3348
MRPS35 -3044
MRPL41 -2920
MRPS21 -2793
MRPL57 -2601
MRPS22 -2326
MRPL37 -2251
MRPS26 -2022
GADD45GIP1 -1746
MRPS23 -1564
MRPL47 -1448
MRPL58 -1009
MRPS34 -978
MRPL2 -971
MRPL27 -697
MRPS16 -360
MT-RNR2 -141
MRPL18 194
MRPL40 273
MRPS18C 334
MRPS15 1207
MRPL21 1215
MRPS36 1368
MRPL13 1696
MRPL20 1881
MRPL22 1912
MRPL44 2241
MRPL36 2321
MRPS18A 2478
MRPS24 2522
MRPL4 2604
ERAL1 3081
MRPL16 3317
MRPL51 4065
OXA1L 4368
MT-TV 4515
MRPS11 4616
MRPL33 4926
MRPL10 5324
AURKAIP1 5462
MRPS5 5888
CHCHD1 6111
TUFM 6200
MRPL23 6696
MRPL53 7456
MRPL52 8490
MRPL28 10313


IRAK4 deficiency (TLR2/4)

IRAK4 deficiency (TLR2/4)
512
set IRAK4 deficiency (TLR2/4)
setSize 10
pANOVA 6.62e-06
s.dist 0.823
p.adjustANOVA 0.000114



Top enriched genes

Top 20 genes
GeneID Gene Rank
MYD88 11614
BTK 11379
CD36 11354
TLR2 10761
CD14 10542
LY96 10002
TLR4 9355
TLR1 8749
TLR6 7631
TIRAP 6862

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MYD88 11614
BTK 11379
CD36 11354
TLR2 10761
CD14 10542
LY96 10002
TLR4 9355
TLR1 8749
TLR6 7631
TIRAP 6862


MyD88 deficiency (TLR2/4)

MyD88 deficiency (TLR2/4)
685
set MyD88 deficiency (TLR2/4)
setSize 10
pANOVA 6.62e-06
s.dist 0.823
p.adjustANOVA 0.000114



Top enriched genes

Top 20 genes
GeneID Gene Rank
MYD88 11614
BTK 11379
CD36 11354
TLR2 10761
CD14 10542
LY96 10002
TLR4 9355
TLR1 8749
TLR6 7631
TIRAP 6862

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MYD88 11614
BTK 11379
CD36 11354
TLR2 10761
CD14 10542
LY96 10002
TLR4 9355
TLR1 8749
TLR6 7631
TIRAP 6862


DNA Repair

DNA Repair
241
set DNA Repair
setSize 289
pANOVA 6.78e-06
s.dist -0.154
p.adjustANOVA 0.000116



Top enriched genes

Top 20 genes
GeneID Gene Rank
UNG -9850
POLD2 -9742
RAD18 -9712
APEX1 -9705
APBB1 -9682
RPA1 -9657
RAD1 -9471
TDP1 -9439
ALKBH3 -9214
PARP1 -9133
WRN -9097
POLE3 -8924
FANCE -8897
XPA -8840
FANCD2 -8817
PALB2 -8731
RPS27A -8722
FANCF -8703
RFC3 -8694
ALKBH2 -8644

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
UNG -9850
POLD2 -9742
RAD18 -9712
APEX1 -9705
APBB1 -9682
RPA1 -9657
RAD1 -9471
TDP1 -9439
ALKBH3 -9214
PARP1 -9133
WRN -9097
POLE3 -8924
FANCE -8897
XPA -8840
FANCD2 -8817
PALB2 -8731
RPS27A -8722
FANCF -8703
RFC3 -8694
ALKBH2 -8644
LIG1 -8618
TP53 -8613
PRPF19 -8548
GEN1 -8219
POLR2D -8160
COPS8 -8134
MAPK8 -8128
RPA3 -8069
HMGN1 -8031
WDR48 -8004
GTF2H3 -7969
RUVBL1 -7856
PAXIP1 -7809
XRCC6 -7770
RAD17 -7742
RFC4 -7736
USP1 -7662
ATM -7513
TCEA1 -7475
MSH2 -7399
FANCM -7344
CHD1L -7306
YY1 -7301
REV1 -7246
GTF2H1 -7185
FEN1 -7122
UBE2T -7093
FANCI -7036
MDC1 -6961
NEIL2 -6950
PCNA -6841
ISG15 -6814
ERCC6 -6781
UBE2L6 -6722
TP53BP1 -6695
POLE2 -6659
FTO -6557
DTL -6528
ERCC5 -6515
H2BC9 -6264
BRIP1 -6240
SMARCA5 -6114
EME1 -6089
USP43 -6037
CHEK1 -6036
H2AZ2 -5901
ZNF830 -5861
POT1 -5841
MNAT1 -5650
DCLRE1A -5533
POLH -5512
RFC1 -5493
FANCB -5424
PARP2 -5385
PRKDC -5261
ACTL6A -5233
MUTYH -5226
POLQ -5114
POLR2B -5111
RAD9A -5073
PPIE -5064
RHNO1 -4965
MRE11 -4960
TERF2 -4926
ACTR5 -4911
INO80E -4789
HERC2 -4759
XPC -4743
USP45 -4725
MSH6 -4708
RPA2 -4620
RNF4 -4522
BLM -4432
NHEJ1 -4383
POLB -4374
XRCC2 -4368
EXO1 -4293
REV3L -4275
FANCL -4177
NEIL3 -4097
RAD51D -4074
RAD50 -4065
PMS2 -4051
DNA2 -4017
RFC5 -3986
ACD -3963
POLR2K -3902
ASCC3 -3894
KPNA2 -3851
RIF1 -3821
TERF1 -3813
FANCG -3752
NEIL1 -3744
CDK2 -3694
POLR2H -3611
BRCA2 -3186
UBE2N -3154
ALKBH5 -3081
ATR -2784
PCLAF -2750
BAZ1B -2724
COPS4 -2709
POLR2C -2566
XRCC3 -2550
XRCC5 -2484
UBB -2442
MSH3 -2416
UBE2V2 -2394
CETN2 -2342
CUL4B -2310
CCNA1 -2231
H2BU1 -2206
ACTR8 -2193
LIG3 -1849
TOPBP1 -1834
H2AC6 -1829
NSD2 -1745
NTHL1 -1736
CCNA2 -1727
TIPIN -1712
PPP5C -1699
GPS1 -1667
RAD51 -1636
POLR2I -1599
ATRIP -1520
POLE -1479
ISY1 -1477
UBA52 -1437
SUMO2 -1222
POLE4 -1186
TERF2IP -1108
INO80D -893
COPS3 -762
TIMELESS -663
GTF2H5 -649
XAB2 -562
CUL4A -561
BARD1 -534
COPS2 -505
SPRTN -461
CLSPN -178
INO80 -49
RCHY1 -45
UBE2B 30
OGG1 43
PARG 84
RNF168 130
RNF8 199
COPS7B 246
XRCC1 380
FAAP24 459
POLM 476
H2BC15 524
UBE2I 587
POLD1 646
FANCC 704
NBN 709
BABAM1 735
GTF2H2 765
DDB1 830
COPS6 898
MGMT 958
USP10 992
PNKP 1052
INO80B 1173
AQR 1282
FAAP20 1290
UBA7 1496
RNF111 1594
ERCC4 1817
RAD51AP1 2077
FAN1 2090
USP7 2097
KAT5 2121
DCLRE1C 2280
GTF2H4 2296
HUS1 2327
FAAP100 2596
MLH1 2650
PPP4R2 2683
RAD23A 2691
ERCC1 2734
CHEK2 2738
POLI 2898
H2AZ1 2960
COPS5 3077
NFRKB 3162
H2BC11 3290
POLR2L 3450
TDG 3593
SUMO1 3612
BRCC3 3628
RBX1 3691
UVSSA 3782
H2BC17 3795
MCRS1 3876
ABL1 4039
TDP2 4046
H2BC4 4239
VCP 4271
BAP1 4304
POLN 4391
INO80C 4422
H2BC5 4435
RAD51C 4501
PIAS1 4569
RMI2 4605
RFC2 4835
UBC 4874
CDK7 4908
ERCC8 4958
DDB2 5186
BRCA1 5214
ELL 5225
POLR2E 5238
ERCC3 5421
SLX4 5466
EME2 5626
POLR2G 5695
POLR2F 5738
RBBP8 5902
TINF2 5948
H2BC12 6101
XRCC4 6153
H2BC21 6180
PIAS3 6361
POLR2A 6387
ASCC2 6510
MBD4 6633
KDM4A 6728
SLX1A 7003
RMI1 7005
POLK 7101
CCNH 7145
SUMO3 7223
DCLRE1B 7248
POLL 7252
ASCC1 7266
RTEL1 7274
MUS81 7283
FANCA 7890
POLR2J 7983
ERCC2 8166
RAD52 8167
SPIDR 8189
EYA3 8248
COPS7A 8689
RAD9B 8706
RAD23B 8738
H2AC20 8783
EP300 8816
MPG 8856
TOP3A 8956
LIG4 8990
PIAS4 9149
MAD2L2 9187
SIRT6 9277
TFPT 9359
UIMC1 9837
KDM4B 9857
NPLOC4 9952
RAD51B 10142
PPP4C 10188
POLD4 10344
ACTB 10419
TRIM25 10901
POLD3 11274
SMUG1 11388
H2AJ 11606


Binding and Uptake of Ligands by Scavenger Receptors

Binding and Uptake of Ligands by Scavenger Receptors
107
set Binding and Uptake of Ligands by Scavenger Receptors
setSize 92
pANOVA 8.56e-06
s.dist -0.268
p.adjustANOVA 0.000144



Top enriched genes

Top 20 genes
GeneID Gene Rank
IGKV3-11 -9443
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
IGKV3-15 -7683
JCHAIN -7676
IGHV1-69 -7589
IGLV3-12 -7540
HSPH1 -7472
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
IGLV7-46 -6955
IGHV3-53 -6692

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IGKV3-11 -9443
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
IGKV3-15 -7683
JCHAIN -7676
IGHV1-69 -7589
IGLV3-12 -7540
HSPH1 -7472
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
IGLV7-46 -6955
IGHV3-53 -6692
IGHV4-34 -6614
IGHV2-5 -6583
IGHV3-48 -5881
IGLC7 -5764
IGLV3-27 -5637
IGHV3-23 -5636
IGLV8-61 -5601
IGHV1-2 -5526
COLEC12 -5383
IGLV1-51 -5296
IGHA1 -5247
IGKC -5232
IGHV3-7 -5228
IGLC2 -5138
HSP90AA1 -5083
IGKV3-20 -5082
IGKV1-33 -4953
IGHV4-39 -4884
IGHV3-30 -4685
SCARF1 -4517
HSP90B1 -4493
IGLV1-47 -4485
SPARC -4397
IGKV1-12 -4392
IGKV2-28 -4281
IGLC1 -4280
IGHV2-70 -4223
IGHV3-11 -3626
IGHV1-46 -3558
SSC5D -3539
IGLV4-69 -3305
IGLV1-40 -3024
IGKV2-30 -2958
IGKV1-17 -2929
HPX -2463
IGHV4-59 -2340
IGLV1-36 -2214
IGHA2 -2084
IGLV3-25 -1935
IGHV3-13 -1600
HYOU1 -1539
IGLV1-44 -1090
HBA1 -867
IGKV2D-28 -728
IGLC3 -403
IGKV3D-20 -305
IGLV10-54 -276
SCARB1 -168
HBB -79
APOE 1230
IGLV2-23 1244
APOL1 1736
COL1A2 2609
IGKV5-2 3051
MSR1 3252
IGLV2-11 3601
IGKV1D-39 3771
CALR 4966
STAB2 5526
FTH1 6366
COL4A2 6618
IGLV7-43 7123
SCGB3A2 9181
ALB 9450
IGKV1-39 9771
FTL 10348
LRP1 11120
CD163 11297
CD36 11354
HP 11572
STAB1 11698
MARCO 11713


Rev-mediated nuclear export of HIV RNA

Rev-mediated nuclear export of HIV RNA
1013
set Rev-mediated nuclear export of HIV RNA
setSize 35
pANOVA 1.17e-05
s.dist -0.428
p.adjustANOVA 0.000193



Top enriched genes

Top 20 genes
GeneID Gene Rank
NDC1 -9817
NUP35 -9626
NUP88 -9430
NUP107 -8801
SEH1L -8792
NUP160 -8699
RANGAP1 -8224
NUP43 -7792
NUP155 -7633
RAN -7577
NUP188 -7295
NUP205 -7051
RANBP1 -6221
POM121C -6074
NUP133 -5674
NUP54 -5340
NUP153 -4433
NUP210 -4373
XPO1 -4204
TPR -4127

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NDC1 -9817
NUP35 -9626
NUP88 -9430
NUP107 -8801
SEH1L -8792
NUP160 -8699
RANGAP1 -8224
NUP43 -7792
NUP155 -7633
RAN -7577
NUP188 -7295
NUP205 -7051
RANBP1 -6221
POM121C -6074
NUP133 -5674
NUP54 -5340
NUP153 -4433
NUP210 -4373
XPO1 -4204
TPR -4127
NUP93 -3163
RANBP2 -3109
RCC1 -3085
NUP42 -2718
POM121 -2295
NUP85 -1717
NUP37 -1424
NUP50 -1242
NUP98 175
NUP62 395
AAAS 627
RAE1 5040
SEC13 6793
NUP58 7628
NUP214 10124


Mitochondrial translation termination

Mitochondrial translation termination
671
set Mitochondrial translation termination
setSize 91
pANOVA 1.17e-05
s.dist -0.266
p.adjustANOVA 0.000193



Top enriched genes

Top 20 genes
GeneID Gene Rank
MRPS30 -9238
MRPS6 -9227
MRPS33 -8868
MRPL50 -8779
MRPS18B -8387
MRPS27 -8372
MRPL17 -7946
MRPS25 -7801
MRPL46 -7776
MRPS17 -7515
MRPL49 -7488
MRPL24 -7374
MRPL48 -7205
MRPL3 -6766
MRPL38 -6536
MT-RNR1 -6484
MRPL1 -6477
MRPS9 -6468
MRPS14 -6456
MRPL35 -6300

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MRPS30 -9238
MRPS6 -9227
MRPS33 -8868
MRPL50 -8779
MRPS18B -8387
MRPS27 -8372
MRPL17 -7946
MRPS25 -7801
MRPL46 -7776
MRPS17 -7515
MRPL49 -7488
MRPL24 -7374
MRPL48 -7205
MRPL3 -6766
MRPL38 -6536
MT-RNR1 -6484
MRPL1 -6477
MRPS9 -6468
MRPS14 -6456
MRPL35 -6300
MRPL45 -6248
MRPS2 -6123
MRPL9 -5999
DAP3 -5995
MRPL32 -5558
MRPL42 -5308
MRPL54 -5211
MRPL11 -5071
MRPS7 -5007
PTCD3 -4586
MRPL14 -4414
MRPL39 -4366
MRPS12 -4356
MRPL30 -4147
MRPS31 -4116
MRPL19 -4110
MRPS28 -3921
MRPL34 -3892
MRPL43 -3700
MRPL55 -3601
MRPL12 -3417
MRPL15 -3362
MRPS10 -3348
MRPS35 -3044
MRPL41 -2920
MRPS21 -2793
MRPL57 -2601
MRRF -2404
MRPS22 -2326
MRPL37 -2251
MRPS26 -2022
GADD45GIP1 -1746
MRPS23 -1564
MRPL47 -1448
MRPL58 -1009
MRPS34 -978
MRPL2 -971
MRPL27 -697
GFM2 -362
MRPS16 -360
MT-RNR2 -141
MRPL18 194
MRPL40 273
MRPS18C 334
MRPS15 1207
MRPL21 1215
MRPS36 1368
MRPL13 1696
MRPL20 1881
MRPL22 1912
MRPL44 2241
MRPL36 2321
MRPS18A 2478
MRPS24 2522
MRPL4 2604
ERAL1 3081
MRPL16 3317
MRPL51 4065
OXA1L 4368
MTRF1L 4426
MT-TV 4515
MRPS11 4616
MRPL33 4926
MRPL10 5324
AURKAIP1 5462
MRPS5 5888
CHCHD1 6111
MRPL23 6696
MRPL53 7456
MRPL52 8490
MRPL28 10313


Clathrin-mediated endocytosis

Clathrin-mediated endocytosis
189
set Clathrin-mediated endocytosis
setSize 127
pANOVA 1.21e-05
s.dist 0.225
p.adjustANOVA 0.000196



Top enriched genes

Top 20 genes
GeneID Gene Rank
AP2A1 11707
AMPH 11449
ARPC1A 11206
ARRB2 11021
EPN1 10994
ITSN1 10929
GRB2 10925
SNX18 10894
DAB2 10889
GRK3 10799
SCARB2 10644
AP2A2 10434
SYNJ1 10251
RAB5C 10197
IGF2R 10077
ARPC5 10048
HGS 9939
TGFA 9932
HIP1 9850
PICALM 9814

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AP2A1 11707
AMPH 11449
ARPC1A 11206
ARRB2 11021
EPN1 10994
ITSN1 10929
GRB2 10925
SNX18 10894
DAB2 10889
GRK3 10799
SCARB2 10644
AP2A2 10434
SYNJ1 10251
RAB5C 10197
IGF2R 10077
ARPC5 10048
HGS 9939
TGFA 9932
HIP1 9850
PICALM 9814
DNM2 9736
TGOLN2 9729
OCRL 9709
LDLR 9568
VAMP7 9561
AP2S1 9504
ARPC3 9484
GRK2 9446
CLTC 9346
GAK 9326
SH3GL1 9314
AGFG1 9305
ARPC4 9223
ARPC2 9212
CLTCL1 9020
PACSIN2 8869
REPS2 8795
CBL 8765
COPS7A 8689
NEDD8 8396
CLTB 8275
VAMP3 8012
CLTA 7680
TOR1B 7635
TOR1A 7549
ACTR2 7352
AP2M1 7323
LRP2 7216
EPS15L1 7199
PIP5K1C 7137
SYT11 7091
FCHO2 6921
ACTR3 6644
SYT2 6082
ARFGAP1 6078
ITSN2 6016
ARRB1 5865
AVPR2 5844
DNM1 5834
GAPVD1 5827
RAB5B 4935
UBC 4874
STAM2 4752
REPS1 4640
VAMP8 4250
SYT1 4178
FNBP1L 4083
NECAP1 3901
EPS15 3853
TF 3776
RAB5A 3708
COPS5 3077
TFRC 3047
FZD4 3002
SNX9 2815
CFTR 2137
SH3KBP1 1675
KIAA0319 1066
AREG 932
COPS6 898
DNAJC6 888
EREG 410
COPS7B 246
EGF 238
STON1 7
VAMP4 -18
FCHO1 -228
DNM3 -250
NECAP2 -326
HBEGF -398
COPS2 -505
UBQLN1 -627
PIK3C2A -690
COPS3 -762
ARF6 -848
UBQLN2 -1116
EPN2 -1150
WASL -1370
UBA52 -1437
GPS1 -1667
FNBP1 -1683
UBB -2442
STAM -2492
EPGN -2690
M6PR -2706
COPS4 -2709
STON2 -3139
AP2B1 -3690
CTTN -4321
SLC2A8 -4567
CD4 -4882
DVL2 -4905
TRIP10 -4971
AAK1 -6772
ADRB2 -6879
VAMP2 -7244
COPS8 -8134
BIN1 -8338
HIP1R -8643
RPS27A -8722
CD3D -8747
PACSIN1 -8985
CD3G -9125
HSPA8 -9166
SYNJ2 -9603
LDLRAP1 -9809
IL7R -9876


EPH-Ephrin signaling

EPH-Ephrin signaling
321
set EPH-Ephrin signaling
setSize 79
pANOVA 1.22e-05
s.dist 0.285
p.adjustANOVA 0.000196



Top enriched genes

Top 20 genes
GeneID Gene Rank
NCSTN 11715
AP2A1 11707
ARPC1A 11206
MMP2 11121
ARPC1B 10956
ITSN1 10929
RAC1 10907
LYN 10893
PSEN1 10871
PAK1 10704
AP2A2 10434
ACTB 10419
MMP9 10322
ARPC5 10048
MYL6 10033
PSENEN 9844
CFL1 9683
SDCBP 9536
AP2S1 9504
ARPC3 9484

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NCSTN 11715
AP2A1 11707
ARPC1A 11206
MMP2 11121
ARPC1B 10956
ITSN1 10929
RAC1 10907
LYN 10893
PSEN1 10871
PAK1 10704
AP2A2 10434
ACTB 10419
MMP9 10322
ARPC5 10048
MYL6 10033
PSENEN 9844
CFL1 9683
SDCBP 9536
AP2S1 9504
ARPC3 9484
CLTC 9346
LIMK1 9261
ARPC4 9223
ARPC2 9212
APH1B 9199
ADAM10 9130
CLTCL1 9020
RHOA 8752
ACTG1 8547
CLTB 8275
LIMK2 8172
CLTA 7680
EPHB3 7574
VAV2 7476
ACTR2 7352
CDC42 7337
AP2M1 7323
MYH10 7202
ROCK1 7020
RASA1 6726
ACTR3 6644
MYH9 6290
DNM1 5834
PAK2 5789
VAV3 5645
ROCK2 5519
MYL12B 4733
EFNA4 4670
APH1A 2205
EPHB2 1756
MYL12A 1747
ARHGEF7 1382
EPHB4 1117
SDC2 231
PAK3 -533
ARHGEF28 -546
EPHB1 -566
MYH11 -619
WASL -1370
TIAM1 -2299
EFNA3 -2380
HRAS -3116
PTK2 -3332
PSEN2 -3426
EPHA2 -3550
AP2B1 -3690
MYL9 -4572
GIT1 -4872
EFNA1 -4924
EFNB1 -5152
SRC -5527
YES1 -5662
EFNA5 -6361
FYN -6619
NCK2 -7245
EPHB6 -7369
KALRN -8904
EPHA1 -9348
EPHA4 -9863


Mitochondrial translation

Mitochondrial translation
668
set Mitochondrial translation
setSize 97
pANOVA 1.26e-05
s.dist -0.257
p.adjustANOVA 0.000199



Top enriched genes

Top 20 genes
GeneID Gene Rank
GFM1 -9259
MRPS30 -9238
MRPS6 -9227
MRPS33 -8868
MRPL50 -8779
MRPS18B -8387
MRPS27 -8372
MRPL17 -7946
MRPS25 -7801
MRPL46 -7776
MRPS17 -7515
MRPL49 -7488
MRPL24 -7374
MRPL48 -7205
MRPL3 -6766
MRPL38 -6536
MT-RNR1 -6484
MRPL1 -6477
MRPS9 -6468
MRPS14 -6456

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GFM1 -9259
MRPS30 -9238
MRPS6 -9227
MRPS33 -8868
MRPL50 -8779
MRPS18B -8387
MRPS27 -8372
MRPL17 -7946
MRPS25 -7801
MRPL46 -7776
MRPS17 -7515
MRPL49 -7488
MRPL24 -7374
MRPL48 -7205
MRPL3 -6766
MRPL38 -6536
MT-RNR1 -6484
MRPL1 -6477
MRPS9 -6468
MRPS14 -6456
MRPL35 -6300
MRPL45 -6248
MRPS2 -6123
MRPL9 -5999
DAP3 -5995
MRPL32 -5558
MRPL42 -5308
MRPL54 -5211
MRPL11 -5071
MRPS7 -5007
PTCD3 -4586
MRPL14 -4414
MRPL39 -4366
MRPS12 -4356
MRPL30 -4147
MRPS31 -4116
MRPL19 -4110
MRPS28 -3921
MRPL34 -3892
MRPL43 -3700
MRPL55 -3601
TSFM -3472
MRPL12 -3417
MRPL15 -3362
MRPS10 -3348
MRPS35 -3044
MRPL41 -2920
MRPS21 -2793
MRPL57 -2601
MRRF -2404
MRPS22 -2326
MRPL37 -2251
MRPS26 -2022
GADD45GIP1 -1746
MRPS23 -1564
MRPL47 -1448
MRPL58 -1009
MRPS34 -978
MRPL2 -971
MRPL27 -697
GFM2 -362
MRPS16 -360
MT-RNR2 -141
MTFMT 190
MRPL18 194
MRPL40 273
MRPS18C 334
MTIF2 475
MRPS15 1207
MRPL21 1215
MRPS36 1368
MRPL13 1696
MRPL20 1881
MRPL22 1912
MRPL44 2241
MRPL36 2321
MRPS18A 2478
MRPS24 2522
MRPL4 2604
ERAL1 3081
MRPL16 3317
MTIF3 3990
MRPL51 4065
OXA1L 4368
MTRF1L 4426
MT-TV 4515
MRPS11 4616
MRPL33 4926
MRPL10 5324
AURKAIP1 5462
MRPS5 5888
CHCHD1 6111
TUFM 6200
MRPL23 6696
MRPL53 7456
MRPL52 8490
MRPL28 10313


Mitochondrial translation initiation

Mitochondrial translation initiation
670
set Mitochondrial translation initiation
setSize 91
pANOVA 1.48e-05
s.dist -0.263
p.adjustANOVA 0.000231



Top enriched genes

Top 20 genes
GeneID Gene Rank
MRPS30 -9238
MRPS6 -9227
MRPS33 -8868
MRPL50 -8779
MRPS18B -8387
MRPS27 -8372
MRPL17 -7946
MRPS25 -7801
MRPL46 -7776
MRPS17 -7515
MRPL49 -7488
MRPL24 -7374
MRPL48 -7205
MRPL3 -6766
MRPL38 -6536
MT-RNR1 -6484
MRPL1 -6477
MRPS9 -6468
MRPS14 -6456
MRPL35 -6300

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MRPS30 -9238
MRPS6 -9227
MRPS33 -8868
MRPL50 -8779
MRPS18B -8387
MRPS27 -8372
MRPL17 -7946
MRPS25 -7801
MRPL46 -7776
MRPS17 -7515
MRPL49 -7488
MRPL24 -7374
MRPL48 -7205
MRPL3 -6766
MRPL38 -6536
MT-RNR1 -6484
MRPL1 -6477
MRPS9 -6468
MRPS14 -6456
MRPL35 -6300
MRPL45 -6248
MRPS2 -6123
MRPL9 -5999
DAP3 -5995
MRPL32 -5558
MRPL42 -5308
MRPL54 -5211
MRPL11 -5071
MRPS7 -5007
PTCD3 -4586
MRPL14 -4414
MRPL39 -4366
MRPS12 -4356
MRPL30 -4147
MRPS31 -4116
MRPL19 -4110
MRPS28 -3921
MRPL34 -3892
MRPL43 -3700
MRPL55 -3601
MRPL12 -3417
MRPL15 -3362
MRPS10 -3348
MRPS35 -3044
MRPL41 -2920
MRPS21 -2793
MRPL57 -2601
MRPS22 -2326
MRPL37 -2251
MRPS26 -2022
GADD45GIP1 -1746
MRPS23 -1564
MRPL47 -1448
MRPL58 -1009
MRPS34 -978
MRPL2 -971
MRPL27 -697
MRPS16 -360
MT-RNR2 -141
MTFMT 190
MRPL18 194
MRPL40 273
MRPS18C 334
MTIF2 475
MRPS15 1207
MRPL21 1215
MRPS36 1368
MRPL13 1696
MRPL20 1881
MRPL22 1912
MRPL44 2241
MRPL36 2321
MRPS18A 2478
MRPS24 2522
MRPL4 2604
ERAL1 3081
MRPL16 3317
MTIF3 3990
MRPL51 4065
OXA1L 4368
MT-TV 4515
MRPS11 4616
MRPL33 4926
MRPL10 5324
AURKAIP1 5462
MRPS5 5888
CHCHD1 6111
MRPL23 6696
MRPL53 7456
MRPL52 8490
MRPL28 10313


Vpr-mediated nuclear import of PICs

Vpr-mediated nuclear import of PICs
1319
set Vpr-mediated nuclear import of PICs
setSize 34
pANOVA 1.5e-05
s.dist -0.429
p.adjustANOVA 0.000232



Top enriched genes

Top 20 genes
GeneID Gene Rank
NDC1 -9817
NUP35 -9626
NUP88 -9430
PSIP1 -8864
NUP107 -8801
SEH1L -8792
NUP160 -8699
HMGA1 -8468
NUP43 -7792
NUP155 -7633
NUP188 -7295
NUP205 -7051
POM121C -6074
NUP133 -5674
NUP54 -5340
NUP153 -4433
NUP210 -4373
BANF1 -4324
KPNA1 -4278
TPR -4127

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NDC1 -9817
NUP35 -9626
NUP88 -9430
PSIP1 -8864
NUP107 -8801
SEH1L -8792
NUP160 -8699
HMGA1 -8468
NUP43 -7792
NUP155 -7633
NUP188 -7295
NUP205 -7051
POM121C -6074
NUP133 -5674
NUP54 -5340
NUP153 -4433
NUP210 -4373
BANF1 -4324
KPNA1 -4278
TPR -4127
NUP93 -3163
RANBP2 -3109
NUP42 -2718
POM121 -2295
NUP85 -1717
NUP37 -1424
NUP50 -1242
NUP98 175
NUP62 395
AAAS 627
RAE1 5040
SEC13 6793
NUP58 7628
NUP214 10124


Antigen processing-Cross presentation

Antigen processing-Cross presentation
73
set Antigen processing-Cross presentation
setSize 97
pANOVA 1.74e-05
s.dist 0.252
p.adjustANOVA 0.000266



Top enriched genes

Top 20 genes
GeneID Gene Rank
MYD88 11614
FCGR1B 11468
BTK 11379
CD36 11354
FCGR1A 11256
CTSL 11213
NCF2 11041
NCF4 10873
TLR2 10761
CYBA 10617
CD14 10542
PSMD4 10295
CYBB 10196
LY96 10002
PSMB3 9902
TLR4 9355
PSMB6 9262
PSMD9 9005
IKBKG 8902
TLR1 8749

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MYD88 11614
FCGR1B 11468
BTK 11379
CD36 11354
FCGR1A 11256
CTSL 11213
NCF2 11041
NCF4 10873
TLR2 10761
CYBA 10617
CD14 10542
PSMD4 10295
CYBB 10196
LY96 10002
PSMB3 9902
TLR4 9355
PSMB6 9262
PSMD9 9005
IKBKG 8902
TLR1 8749
PSMD6 8745
PSMA7 8719
PSMB5 8625
STX4 8182
ITGAV 8115
VAMP3 8012
PSMB7 7941
SEM1 7739
TLR6 7631
NCF1 7481
CTSS 7190
CHUK 7179
PSMD11 7057
TIRAP 6862
MRC1 6666
PSME3 6605
PSMD1 6354
PSMD5 6029
PSMC1 5778
PSMD12 5714
PSMD2 5544
PSMD8 5474
PSMB8 5433
IKBKB 5156
CALR 4966
UBC 4874
PSMB2 4680
SEC61B 4523
PSMC2 4457
SNAP23 4343
PSMA6 4263
VAMP8 4250
PSMD3 4177
TAPBP 4012
SEC61A1 3976
PSMD13 3770
PSMB4 3707
PSMC6 3483
PSMA1 3451
HLA-C 3114
PDIA3 2874
HLA-B 2308
PSMC3 2182
SEC22B 2167
PSMD7 1547
PSMC4 1389
PSMF1 1056
PSMD14 225
PSMA4 -118
PSMB10 -372
CTSV -594
PSME4 -1087
TAP2 -1094
HLA-H -1311
UBA52 -1437
PSMB1 -1960
PSMA2 -2032
HLA-F -2235
SEC61G -2328
UBB -2442
HLA-E -2458
MRC2 -2568
HLA-G -3238
SEC61A2 -3262
PSME2 -3570
ITGB5 -3701
LNPEP -3755
PSMA3 -4338
PSMD10 -4578
HLA-A -5456
TAP1 -5549
PSMC5 -5909
PSMA5 -6362
PSME1 -6399
B2M -7346
PSMB9 -7625
RPS27A -8722


Phosphorylation of CD3 and TCR zeta chains

Phosphorylation of CD3 and TCR zeta chains
820
set Phosphorylation of CD3 and TCR zeta chains
setSize 27
pANOVA 1.96e-05
s.dist -0.475
p.adjustANOVA 0.000296



Top enriched genes

Top 20 genes
GeneID Gene Rank
TRBV12-3 -9724
CD247 -9497
LCK -9485
HLA-DQA2 -9407
TRAV19 -9396
CD3E -9378
TRAC -9330
CD3G -9125
HLA-DQB2 -9021
CD3D -8747
TRBC1 -8666
TRAV29DV5 -8326
TRAV8-4 -7607
HLA-DPB1 -7109
TRBV7-9 -6741
HLA-DRA -6613
HLA-DPA1 -5854
CD4 -4882
HLA-DQA1 -1465
HLA-DRB5 -1119

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TRBV12-3 -9724
CD247 -9497
LCK -9485
HLA-DQA2 -9407
TRAV19 -9396
CD3E -9378
TRAC -9330
CD3G -9125
HLA-DQB2 -9021
CD3D -8747
TRBC1 -8666
TRAV29DV5 -8326
TRAV8-4 -7607
HLA-DPB1 -7109
TRBV7-9 -6741
HLA-DRA -6613
HLA-DPA1 -5854
CD4 -4882
HLA-DQA1 -1465
HLA-DRB5 -1119
PAG1 322
HLA-DRB1 1353
HLA-DQB1 3660
PTPN22 5604
PTPRC 7546
PTPRJ 9428
CSK 10310


RHO GTPases Activate WASPs and WAVEs

RHO GTPases Activate WASPs and WAVEs
888
set RHO GTPases Activate WASPs and WAVEs
setSize 35
pANOVA 2.11e-05
s.dist 0.415
p.adjustANOVA 0.000316



Top enriched genes

Top 20 genes
GeneID Gene Rank
WASF1 11510
NCKAP1L 11401
BTK 11379
WAS 11238
ARPC1A 11206
CYFIP1 11117
ARPC1B 10956
GRB2 10925
RAC1 10907
MAPK1 10847
ACTB 10419
WASF2 10259
ARPC5 10048
MAPK3 9636
ARPC3 9484
ARPC4 9223
ARPC2 9212
ACTG1 8547
NCKAP1 7871
ABI1 7663

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
WASF1 11510
NCKAP1L 11401
BTK 11379
WAS 11238
ARPC1A 11206
CYFIP1 11117
ARPC1B 10956
GRB2 10925
RAC1 10907
MAPK1 10847
ACTB 10419
WASF2 10259
ARPC5 10048
MAPK3 9636
ARPC3 9484
ARPC4 9223
ARPC2 9212
ACTG1 8547
NCKAP1 7871
ABI1 7663
ACTR2 7352
CDC42 7337
WIPF2 6706
ACTR3 6644
ABL1 4039
BAIAP2 -1231
WASL -1370
BRK1 -2011
PTK2 -3332
WIPF1 -3530
CYFIP2 -4772
WASF3 -6482
NCKIPSD -6991
ABI2 -7811
NCK1 -8821


trans-Golgi Network Vesicle Budding

trans-Golgi Network Vesicle Budding
1362
set trans-Golgi Network Vesicle Budding
setSize 69
pANOVA 2.39e-05
s.dist 0.294
p.adjustANOVA 0.000353



Top enriched genes

Top 20 genes
GeneID Gene Rank
GNS 11592
BLOC1S1 11348
AP1B1 10946
AP1S1 10842
CTSZ 10773
CHMP2A 10625
ARF1 10356
FTL 10348
RAB5C 10197
AP1M1 10145
IGF2R 10077
AP4M1 10058
SORT1 10018
CPD 9940
HGS 9939
PICALM 9814
DNM2 9736
TGOLN2 9729
OCRL 9709
VAMP7 9561

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GNS 11592
BLOC1S1 11348
AP1B1 10946
AP1S1 10842
CTSZ 10773
CHMP2A 10625
ARF1 10356
FTL 10348
RAB5C 10197
AP1M1 10145
IGF2R 10077
AP4M1 10058
SORT1 10018
CPD 9940
HGS 9939
PICALM 9814
DNM2 9736
TGOLN2 9729
OCRL 9709
VAMP7 9561
SNX2 9523
CLTC 9346
GAK 9326
SNAPIN 8619
NAPA 8477
CLTB 8275
STX4 8182
CLTA 7680
DNASE2 6747
FTH1 6366
GBF1 6282
SNX5 6119
ARRB1 5865
AP3B1 5406
YIPF6 5187
PUM1 4404
SNAP23 4343
VAMP8 4250
NECAP1 3901
AP1G1 3828
TPD52L1 3634
APP 3315
TBC1D8B 3146
AP3S1 3106
TFRC 3047
SNX9 2815
AP4E1 2808
AP1S3 1783
AP4B1 1250
CLINT1 1115
DNAJC6 888
AP1G2 471
ACBD3 -610
PIK3C2A -690
BLOC1S6 -1527
AP4S1 -1900
BLOC1S3 -2366
M6PR -2706
DTNBP1 -3111
SH3D19 -3800
GOLGB1 -4180
TXNDC5 -4205
BLOC1S4 -7101
VAMP2 -7244
AP1M2 -7416
AP1S2 -7941
HIP1R -8643
HSPA8 -9166
TPD52 -9559


Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)

Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
956
set Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
setSize 81
pANOVA 2.53e-05
s.dist 0.271
p.adjustANOVA 0.000371



Top enriched genes

Top 20 genes
GeneID Gene Rank
FAM20A 11746
SERPINA1 11685
LGALS1 11621
F5 11617
LAMC1 11585
QSOX1 11547
PCSK9 11538
TIMP1 11482
FSTL3 11400
LAMB1 11317
VCAN 11287
FAM20C 11139
MMP2 11121
APLP2 11071
IGFBP7 10909
TMEM132A 10607
NUCB1 10433
GAS6 10432
APOA2 10312
PNPLA2 10177

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FAM20A 11746
SERPINA1 11685
LGALS1 11621
F5 11617
LAMC1 11585
QSOX1 11547
PCSK9 11538
TIMP1 11482
FSTL3 11400
LAMB1 11317
VCAN 11287
FAM20C 11139
MMP2 11121
APLP2 11071
IGFBP7 10909
TMEM132A 10607
NUCB1 10433
GAS6 10432
APOA2 10312
PNPLA2 10177
CKAP4 10088
IGFBP6 9936
TGOLN2 9729
MELTF 9482
ALB 9450
P4HB 9433
ADAM10 9130
SERPIND1 8628
MBTPS1 8506
CP 8474
CALU 8310
DNAJC3 8291
ITIH2 8063
PROC 7786
ANO8 6828
SHISA5 6722
FUCA2 6509
SERPINA10 6256
PRKCSH 5698
MSLN 5574
KLK2 4937
IGFALS 4627
TF 3776
CST3 3572
APP 3315
TNC 3001
ENAM 2889
LAMB2 2581
C3 1898
C4A 1786
APOL1 1736
PDIA6 1471
FGF23 1439
PLG 1297
APOE 1230
IGFBP2 1222
IGFBP4 1179
SDC2 231
KTN1 -374
GOLM1 -1349
FN1 -1748
FBN1 -2384
MMP1 -2443
FSTL1 -3115
LTBP1 -3123
GZMH -3208
MFGE8 -3307
MEN1 -3826
MIA3 -3981
HSP90B1 -4493
CSF1 -5020
CTSG -5681
RCN1 -6230
MXRA8 -6680
PAPPA -7434
KLK1 -8106
BMP4 -8222
WFS1 -8508
PRSS23 -8529
MGAT4A -9187
IGFBP3 -9434


FCERI mediated MAPK activation

FCERI mediated MAPK activation
359
set FCERI mediated MAPK activation
setSize 90
pANOVA 2.82e-05
s.dist -0.255
p.adjustANOVA 0.000409



Top enriched genes

Top 20 genes
GeneID Gene Rank
IGKV3-11 -9443
LAT -9159
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
PLCG1 -8497
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
MAPK8 -8128
IGKV3-15 -7683
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
IGLV7-46 -6955

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IGKV3-11 -9443
LAT -9159
IGLV6-57 -8979
IGLV5-45 -8955
IGLV2-18 -8778
IGLV2-14 -8599
IGHV3-33 -8574
PLCG1 -8497
IGKV1-16 -8350
IGLV3-21 -8327
IGLV3-1 -8150
MAPK8 -8128
IGKV3-15 -7683
IGHV1-69 -7589
IGLV3-12 -7540
IGLV2-8 -7468
IGKV1-5 -7365
IGLV3-19 -7358
IGKV4-1 -7302
IGLV7-46 -6955
IGHV3-53 -6692
IGHV4-34 -6614
IGHV2-5 -6583
GRAP2 -6236
IGHE -6130
MAPK9 -5918
IGHV3-48 -5881
IGLC7 -5764
IGLV3-27 -5637
IGHV3-23 -5636
IGLV8-61 -5601
IGHV1-2 -5526
IGLV1-51 -5296
IGKC -5232
IGHV3-7 -5228
IGLC2 -5138
IGKV3-20 -5082
IGKV1-33 -4953
IGHV4-39 -4884
IGHV3-30 -4685
IGLV1-47 -4485
IGKV1-12 -4392
IGKV2-28 -4281
IGLC1 -4280
IGHV2-70 -4223
FOS -3812
IGHV3-11 -3626
IGHV1-46 -3558
IGLV4-69 -3305
SOS1 -3263
HRAS -3116
IGLV1-40 -3024
IGKV2-30 -2958
IGKV1-17 -2929
IGHV4-59 -2340
IGLV1-36 -2214
IGLV3-25 -1935
IGHV3-13 -1600
JUN -1440
IGLV1-44 -1090
IGKV2D-28 -728
IGLC3 -403
IGKV3D-20 -305
IGLV10-54 -276
LCP2 514
MAP2K7 1099
IGLV2-23 1244
NRAS 1826
IGKV5-2 3051
KRAS 3113
IGLV2-11 3601
IGKV1D-39 3771
MAP2K4 4579
MAP3K1 4584
VAV3 5645
PAK2 5789
IGLV7-43 7123
VAV2 7476
SHC1 7938
MAPK3 9636
IGKV1-39 9771
SYK 10086
VAV1 10149
MAPK10 10215
PLCG2 10376
PAK1 10704
MAPK1 10847
LYN 10893
RAC1 10907
GRB2 10925


Nuclear import of Rev protein

Nuclear import of Rev protein
752
set Nuclear import of Rev protein
setSize 34
pANOVA 2.89e-05
s.dist -0.414
p.adjustANOVA 0.000414



Top enriched genes

Top 20 genes
GeneID Gene Rank
NPM1 -9836
NDC1 -9817
NUP35 -9626
NUP88 -9430
NUP107 -8801
SEH1L -8792
NUP160 -8699
NUP43 -7792
NUP155 -7633
RAN -7577
NUP188 -7295
NUP205 -7051
POM121C -6074
NUP133 -5674
NUP54 -5340
NUP153 -4433
NUP210 -4373
TPR -4127
NUP93 -3163
RANBP2 -3109

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NPM1 -9836
NDC1 -9817
NUP35 -9626
NUP88 -9430
NUP107 -8801
SEH1L -8792
NUP160 -8699
NUP43 -7792
NUP155 -7633
RAN -7577
NUP188 -7295
NUP205 -7051
POM121C -6074
NUP133 -5674
NUP54 -5340
NUP153 -4433
NUP210 -4373
TPR -4127
NUP93 -3163
RANBP2 -3109
RCC1 -3085
NUP42 -2718
POM121 -2295
NUP85 -1717
NUP37 -1424
NUP50 -1242
KPNB1 -109
NUP98 175
NUP62 395
AAAS 627
RAE1 5040
SEC13 6793
NUP58 7628
NUP214 10124


Detoxification of Reactive Oxygen Species

Detoxification of Reactive Oxygen Species
277
set Detoxification of Reactive Oxygen Species
setSize 32
pANOVA 3.05e-05
s.dist 0.426
p.adjustANOVA 0.000433



Top enriched genes

Top 20 genes
GeneID Gene Rank
NCF2 11041
NCF4 10873
GSR 10772
PRDX3 10709
CYBA 10617
CYBB 10196
P4HB 9433
CAT 9425
GPX3 9342
PRDX5 8681
TXN 8653
SOD2 8563
TXNRD1 8216
NOX4 8004
NOX5 7998
TXNRD2 7888
NCF1 7481
ATOX1 6597
ERO1A 6518
GPX2 6305

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NCF2 11041
NCF4 10873
GSR 10772
PRDX3 10709
CYBA 10617
CYBB 10196
P4HB 9433
CAT 9425
GPX3 9342
PRDX5 8681
TXN 8653
SOD2 8563
TXNRD1 8216
NOX4 8004
NOX5 7998
TXNRD2 7888
NCF1 7481
ATOX1 6597
ERO1A 6518
GPX2 6305
PRDX1 5934
TXN2 5240
GPX1 5066
ATP7A 2494
CCS 2233
NUDT2 1834
GSTP1 1776
PRDX6 -823
PRDX2 -4140
CYCS -4630
SOD1 -5860
GPX7 -9452


COPI-mediated anterograde transport

COPI-mediated anterograde transport
132
set COPI-mediated anterograde transport
setSize 78
pANOVA 3.17e-05
s.dist 0.272
p.adjustANOVA 0.000445



Top enriched genes

Top 20 genes
GeneID Gene Rank
COG7 11491
COPG1 11346
GORASP1 10996
CD55 10741
DCTN2 10458
ARF1 10356
ACTR1A 10067
RAB1A 9919
NSF 9858
COPA 9848
TMED9 9614
ARF5 9584
KDELR1 9578
DCTN4 9451
RAB1B 9447
DCTN6 9325
DCTN1 9214
ARF4 9156
COG4 9044
COPE 8787

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
COG7 11491
COPG1 11346
GORASP1 10996
CD55 10741
DCTN2 10458
ARF1 10356
ACTR1A 10067
RAB1A 9919
NSF 9858
COPA 9848
TMED9 9614
ARF5 9584
KDELR1 9578
DCTN4 9451
RAB1B 9447
DCTN6 9325
DCTN1 9214
ARF4 9156
COG4 9044
COPE 8787
NAPG 8778
COPG2 8671
ARF3 8602
CAPZB 8593
NAPA 8477
GOLGA2 8366
DYNC1LI2 8092
STX5 8070
CAPZA1 8032
CAPZA2 7999
DCTN3 7885
DYNC1LI1 7881
ARFGAP2 6724
COPB2 6710
YKT6 6467
GBF1 6282
COPB1 6181
ARFGAP1 6078
DYNC1I2 5729
SPTBN5 5455
KDELR2 4945
ACTR10 4228
TMEM115 3887
TMED3 3759
NAPB 3641
SPTB 3448
ARFGAP3 3442
DYNLL1 3185
COPZ1 2925
GOSR2 2697
ARCN1 1716
SPTA1 1589
DYNC1I1 1191
TMED2 965
KDELR3 810
ANK1 741
COG5 706
SPTBN2 565
USO1 -110
DCTN5 -898
DYNC1H1 -1040
TMED7 -1318
COG8 -1340
COG2 -2945
CD59 -3215
BET1L -3403
COG3 -3840
GOLGB1 -4180
BET1 -5288
COG1 -5406
COG6 -5508
ANK3 -5980
GOSR1 -6194
COPZ2 -6311
TMED10 -6868
DYNLL2 -8015
SPTBN1 -8685
SPTAN1 -9516


NS1 Mediated Effects on Host Pathways

NS1 Mediated Effects on Host Pathways
712
set NS1 Mediated Effects on Host Pathways
setSize 40
pANOVA 3.22e-05
s.dist -0.38
p.adjustANOVA 0.000448



Top enriched genes

Top 20 genes
GeneID Gene Rank
NDC1 -9817
NUP35 -9626
NUP88 -9430
NUP107 -8801
SEH1L -8792
NUP160 -8699
NUP43 -7792
NUP155 -7633
KPNA5 -7556
NUP188 -7295
NUP205 -7051
ISG15 -6814
POM121C -6074
NUP133 -5674
NUP54 -5340
NUP153 -4433
NUP210 -4373
KPNA1 -4278
KPNA3 -4263
TPR -4127

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NDC1 -9817
NUP35 -9626
NUP88 -9430
NUP107 -8801
SEH1L -8792
NUP160 -8699
NUP43 -7792
NUP155 -7633
KPNA5 -7556
NUP188 -7295
NUP205 -7051
ISG15 -6814
POM121C -6074
NUP133 -5674
NUP54 -5340
NUP153 -4433
NUP210 -4373
KPNA1 -4278
KPNA3 -4263
TPR -4127
KPNA2 -3851
NUP93 -3163
RANBP2 -3109
NUP42 -2718
CPSF4 -2319
POM121 -2295
NUP85 -1717
NUP37 -1424
NUP50 -1242
KPNA4 -701
KPNB1 -109
NUP98 175
NUP62 395
EIF2AK2 426
AAAS 627
PABPN1 2573
RAE1 5040
SEC13 6793
NUP58 7628
NUP214 10124


Signaling by Receptor Tyrosine Kinases

Signaling by Receptor Tyrosine Kinases
1131
set Signaling by Receptor Tyrosine Kinases
setSize 414
pANOVA 3.9e-05
s.dist 0.118
p.adjustANOVA 0.000536



Top enriched genes

Top 20 genes
GeneID Gene Rank
MAPKAPK3 11720
NCSTN 11715
TCIRG1 11708
AP2A1 11707
SH2B2 11620
GRB10 11589
LAMC1 11585
CTNNA1 11582
PRKACA 11578
ATP6AP1 11518
WASF1 11510
PRKCD 11506
PTK2B 11504
ATP6V0A1 11467
FLT1 11450
ADAM17 11419
CDK5 11415
NCKAP1L 11401
LAMB1 11317
FES 11299

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MAPKAPK3 11720
NCSTN 11715
TCIRG1 11708
AP2A1 11707
SH2B2 11620
GRB10 11589
LAMC1 11585
CTNNA1 11582
PRKACA 11578
ATP6AP1 11518
WASF1 11510
PRKCD 11506
PTK2B 11504
ATP6V0A1 11467
FLT1 11450
ADAM17 11419
CDK5 11415
NCKAP1L 11401
LAMB1 11317
FES 11299
ATP6V0D1 11283
PTPN6 11254
PTPN18 11205
CYFIP1 11117
NCF2 11041
PTPRO 11020
EPN1 10994
STAT6 10986
RPS6KA1 10944
GRB2 10925
RAC1 10907
LYN 10893
NCF4 10873
PSEN1 10871
ATP6V0C 10858
MAPK1 10847
DLG4 10839
TEC 10815
RNF41 10711
PAK1 10704
ID2 10672
CYBA 10617
ADAP1 10588
ATP6V0B 10507
SPRED2 10481
SPHK1 10467
MAPK14 10466
AP2A2 10434
PTPN2 10427
MAPK7 10339
MMP9 10322
HGF 10314
FURIN 10311
CSK 10310
WASF2 10259
THBS3 10258
MAP2K1 10244
GAB2 10228
RAB4B 10224
RIT1 10201
CYBB 10196
VAV1 10149
TNS3 10109
CDH5 10039
FGFR1 10016
HGS 9939
TGFA 9932
ELMO2 9846
PSENEN 9844
MKNK1 9829
SPINT1 9778
FLT3 9764
PTPN1 9752
DNM2 9736
GAB1 9727
ATP6V1D 9706
ATP6V1B2 9701
MAPK3 9636
GGA3 9615
AP2S1 9504
LYL1 9490
RALB 9488
PTPRJ 9428
CRK 9373
SH2B3 9368
CLTC 9346
SH3GL1 9314
IRS2 9312
INSR 9283
ANOS1 9278
PRKCE 9268
APH1B 9199
ADAM10 9130
STAT5A 9106
BAX 9079
DUSP3 9049
KL 9001
PTK6 8980
EP300 8816
ATP6V1C1 8809
CBL 8765
RHOA 8752
MEF2A 8747
FRS3 8680
SPRED1 8630
DOCK1 8538
PXN 8537
ATP6V1A 8486
NEDD4 8443
ATP6V0E1 8302
STAT3 8289
PDGFRA 8251
CTNNB1 8119
ITGAV 8115
POLR2J 7983
SHC1 7938
NCKAP1 7871
SOCS6 7813
SHB 7785
COL9A3 7774
CLTA 7680
ABI1 7663
ATP6V1E1 7588
MEMO1 7551
NCF1 7481
VAV2 7476
PTPRU 7411
KIDINS220 7361
MST1 7348
CDC42 7337
AP2M1 7323
COL6A3 7276
MAPK13 7251
EPS15L1 7199
PRKCB 7102
RAP1A 7021
ROCK1 7020
SRF 6879
TRIB1 6781
RASA1 6726
SOCS1 6664
VRK3 6628
COL4A2 6618
USP8 6529
MAPKAPK2 6495
POLR2A 6387
FOSL1 6275
PIK3R2 6269
ERBB3 6166
ITPR2 6136
AKT1 6133
PIK3CB 6109
HPN 6059
GABRB3 6023
NCOR1 5849
DNM1 5834
PAK2 5789
PDPK1 5768
POLR2F 5738
POLR2G 5695
VAV3 5645
PCSK5 5618
SPINT2 5557
LAMA1 5521
ROCK2 5519
GTF2F1 5494
NRP1 5491
MEF2D 5425
AKT2 5390
PPP2CB 5377
RAP1B 5363
CDC37 5325
GTF2F2 5263
POLR2E 5238
ATP6V1F 5145
NTRK3 5134
MAP2K2 5079
ATP6V1H 5047
TNS4 4891
PPP2CA 4882
UBC 4874
MAP2K5 4867
ESRP2 4785
STAM2 4752
PPP2R1A 4593
NAB1 4586
PDGFC 4543
GALNT3 4481
STAT5B 4460
CTNND1 4266
PTPN12 4198
VEGFA 4174
AHCYL1 4099
ATF1 4020
RANBP10 3936
EPS15 3853
RAPGEF1 3848
JAK2 3783
TF 3776
ID1 3596
POLR2L 3450
GFAP 3341
LAMB3 3302
HNRNPM 3201
KRAS 3113
LAMA4 3107
VEGFC 2920
PTPN11 2859
PIK3R3 2799
LAMA5 2789
PDGFRB 2740
LAMB2 2581
GABRG2 2556
PPP2R5D 2555
DIAPH1 2357
MAPKAP1 2319
FLRT2 2238
APH1A 2205
YWHAB 2038
ITCH 1890
NRAS 1826
MAPK12 1731
SH3KBP1 1675
TCF12 1625
PDGFA 1502
FGF23 1439
RANBP9 1414
JUNB 1397
ARHGEF7 1382
PLG 1297
APOE 1230
MTOR 1162
COL9A2 1090
EGR3 1036
FGFRL1 970
AREG 932
THBS1 710
PTPN3 566
NELFB 490
BRAF 421
EREG 410
PAG1 322
EGF 238
MLST8 236
PCSK6 51
FGFBP3 -172
CRKL -238
DNM3 -250
MAPK11 -273
FER -304
HBEGF -398
MST1R -468
PAK3 -533
PGF -599
DNAL4 -616
NRG4 -681
IGF1R -685
AXL -788
ARF6 -848
NAB2 -877
NCBP1 -1125
PIK3CA -1131
PLAT -1179
BAIAP2 -1231
HNRNPF -1277
TRIB3 -1365
ELMO1 -1412
UBA52 -1437
POLR2I -1599
RPS6KA2 -1720
REST -1750
TIA1 -2004
BRK1 -2011
HSPB1 -2023
TLR9 -2033
FGF22 -2040
JUP -2056
ATP6V1C2 -2065
TIAM1 -2299
STUB1 -2360
EGR2 -2386
ADORA2A -2389
UBB -2442
COL4A3 -2471
STAM -2492
CUL5 -2538
FOSB -2552
POLR2C -2566
DUSP4 -2651
EPGN -2690
DOCK7 -2815
ITGB3 -2871
PPP2R1B -2904
TIAL1 -2918
MXD4 -2968
HRAS -3116
COL4A4 -3164
DUSP6 -3175
DUSP7 -3183
SOS1 -3263
PIK3C3 -3291
AAMP -3318
PTK2 -3332
RAB4A -3411
PSEN2 -3426
RPS6KA3 -3451
SPRY2 -3503
TAB2 -3529
CHD4 -3602
POLR2H -3611
S100B -3661
AP2B1 -3690
CAV1 -3722
FGFR2 -3732
CREB1 -3751
MEF2C -3791
ITPR1 -3809
FOS -3812
ERBIN -3881
POLR2K -3902
JUND -4061
FRS2 -4166
PTBP1 -4302
SPARC -4397
PIK3R4 -4411
CDK5R1 -4421
ATP6V1G1 -4463
SHC2 -4611
HNRNPH1 -4617
CYFIP2 -4772
ITGB1 -4850
ESR1 -4853
ATP6V0A2 -4935
ATF2 -4941
PTPRS -5011
HSP90AA1 -5083
POLR2B -5111
CALM1 -5150
ID3 -5210
SGK1 -5363
FLT4 -5370
SRC -5527
FGFR4 -5531
TPH1 -5593
YES1 -5662
PRKCA -5667
ITPR3 -5727
ATP6V1E2 -5845
RICTOR -5883
CHEK1 -6036
ITGA2 -6200
GRAP2 -6236
SH2D2A -6243
DOCK3 -6402
WASF3 -6482
PRKCZ -6483
FYN -6619
MUC20 -6632
LAMA2 -6698
IRS1 -6714
CILP -6767
NOS3 -6838
NRP2 -6855
EGR1 -6878
ELK1 -6971
THBS4 -6990
RALGDS -7168
RPS6KA5 -7223
NCK2 -7245
SHC3 -7255
SPRY1 -7280
FGF2 -7401
NTRK1 -7460
HNRNPA1 -7469
ITGA3 -7485
WWOX -7721
ABI2 -7811
RALA -7942
COL6A1 -8045
ATP6V1G2 -8049
FGF7 -8090
FGFBP2 -8104
POLR2D -8160
NCBP2 -8212
ATP6V0E2 -8351
PLCG1 -8497
STMN1 -8651
FGF9 -8705
RPS27A -8722
PDGFD -8723
PTPRK -8736
AKT3 -8761
ERBB2 -8774
NCK1 -8821
RBFOX2 -8945
PRR5 -9001
NRG1 -9069
MATK -9109
PDE3B -9128
COL6A2 -9201
PIK3R1 -9306
VEGFB -9310
LRIG1 -9376
STAT1 -9404
FLT3LG -9470
LCK -9485
LAMC3 -9573
THEM4 -9622
WWP1 -9624
PRKACB -9741
PDGFB -9807
ADAM12 -9819
KIT -9844
GRAP -9868


SUMOylation

SUMOylation
1043
set SUMOylation
setSize 165
pANOVA 5.95e-05
s.dist -0.181
p.adjustANOVA 0.000807



Top enriched genes

Top 20 genes
GeneID Gene Rank
NPM1 -9836
NDC1 -9817
NR3C2 -9761
RPA1 -9657
NUP35 -9626
RORA -9585
NUP88 -9430
NOP58 -9366
DNMT1 -9203
PARP1 -9133
WRN -9097
SATB1 -9006
EID3 -8972
SIN3A -8913
ZNF131 -8847
NUP107 -8801
SEH1L -8792
BMI1 -8707
NUP160 -8699
TP53 -8613

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NPM1 -9836
NDC1 -9817
NR3C2 -9761
RPA1 -9657
NUP35 -9626
RORA -9585
NUP88 -9430
NOP58 -9366
DNMT1 -9203
PARP1 -9133
WRN -9097
SATB1 -9006
EID3 -8972
SIN3A -8913
ZNF131 -8847
NUP107 -8801
SEH1L -8792
BMI1 -8707
NUP160 -8699
TP53 -8613
NSMCE3 -8524
CASP8AP2 -8373
UBA2 -8263
SAE1 -8251
SCMH1 -8236
RANGAP1 -8224
TRIM28 -7995
NUP43 -7792
NUP155 -7633
NUP188 -7295
CBX5 -7291
HDAC2 -7259
NUP205 -7051
CHD3 -7016
MDC1 -6961
PCNA -6841
PHC1 -6810
L3MBTL2 -6802
TP53BP1 -6695
STAG1 -6554
TOP2B -6452
THRA -6404
NSMCE4A -6327
RAD21 -6258
SUZ12 -6160
POM121C -6074
THRB -5858
SMC3 -5758
NUP133 -5674
NR2C1 -5634
NUP54 -5340
SMC5 -5331
UHRF2 -4899
ESR1 -4853
HERC2 -4759
XPC -4743
NR4A2 -4739
DNMT3A -4737
NUP153 -4433
BLM -4432
NUP210 -4373
SENP1 -4351
TPR -4127
TOP2A -4125
NR3C1 -4034
DDX5 -3820
DAXX -3631
PHC3 -3455
NUP93 -3163
TOPORS -3121
RANBP2 -3109
NUP42 -2718
CDCA8 -2626
RELA -2563
ZNF350 -2515
STAG2 -2436
CETN2 -2342
POM121 -2295
RNF2 -2168
HIC1 -1984
RWDD3 -1904
CBX2 -1835
SENP5 -1760
NUP85 -1717
MTA1 -1577
NUP37 -1424
PIAS2 -1274
NUP50 -1242
SUMO2 -1222
PPARGC1A -1095
RING1 -731
DDX17 -717
SMC1A -662
INCENP -614
ING2 -428
BIRC5 -333
RNF168 130
NUP98 175
NUP62 395
UBE2I 587
VHL 591
AAAS 627
AURKB 781
PPARA 838
SMC6 891
NSMCE2 968
ZBED1 1241
PCGF2 1249
NFKB2 1272
NRIP1 1494
NCOA1 1719
SAFB 1922
SENP2 1946
HDAC1 2347
CTBP1 2394
CBX8 2485
PARK7 2507
PML 2526
HNRNPK 2644
AURKA 3271
DNMT3B 3281
HNRNPC 3313
TOP1 3549
TDG 3593
NSMCE1 3594
SUMO1 3612
NFKBIA 3946
SP3 3964
NCOA2 4313
CDKN2A 4560
PIAS1 4569
AR 4651
CBX4 4754
RAE1 5040
BRCA1 5214
HDAC7 5441
NR1H3 5458
MDM2 5532
CREBBP 5593
MBD1 5656
XRCC4 6153
PIAS3 6361
SEC13 6793
SUMO3 7223
NUP58 7628
HIPK2 8076
RAD52 8167
MITF 8358
IKBKE 8629
EP300 8816
IKBKG 8902
SP100 9018
PIAS4 9149
NR1H2 9385
NUP214 10124
TRIM27 10133
RXRA 10309
HDAC4 10451
SATB2 10563
MRTFA 11149
PHC2 11185
RARA 11226
NCOR2 11380
PPARG 11631
VDR 11663


Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.0.3 (2020-10-10)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 20.04.2 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.9.0
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.9.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.2.0               GGally_2.1.1               
##  [3] beeswarm_0.3.1              gtools_3.8.2               
##  [5] echarts4r_0.4.0             topconfects_1.6.0          
##  [7] limma_3.46.0                eulerr_6.1.0               
##  [9] mitch_1.2.2                 MASS_7.3-53.1              
## [11] fgsea_1.16.0                gplots_3.1.1               
## [13] DESeq2_1.30.0               SummarizedExperiment_1.20.0
## [15] Biobase_2.50.0              MatrixGenerics_1.2.0       
## [17] matrixStats_0.58.0          GenomicRanges_1.42.0       
## [19] GenomeInfoDb_1.26.0         IRanges_2.24.0             
## [21] S4Vectors_0.28.0            BiocGenerics_0.36.0        
## [23] reshape2_1.4.4              forcats_0.5.1              
## [25] stringr_1.4.0               dplyr_1.0.5                
## [27] purrr_0.3.4                 readr_1.4.0                
## [29] tidyr_1.1.3                 tibble_3.1.0               
## [31] ggplot2_3.3.3               tidyverse_1.3.0            
## [33] zoo_1.8-9                  
## 
## loaded via a namespace (and not attached):
##   [1] colorspace_2.0-0       ellipsis_0.3.1         rprojroot_2.0.2       
##   [4] XVector_0.30.0         fs_1.5.0               rstudioapi_0.13       
##   [7] farver_2.1.0           bit64_4.0.5            AnnotationDbi_1.52.0  
##  [10] fansi_0.4.2            lubridate_1.7.10       xml2_1.3.2            
##  [13] splines_4.0.3          cachem_1.0.4           geneplotter_1.68.0    
##  [16] knitr_1.31             polyclip_1.10-0        jsonlite_1.7.2        
##  [19] broom_0.7.5            annotate_1.68.0        dbplyr_2.1.0          
##  [22] shiny_1.6.0            compiler_4.0.3         httr_1.4.2            
##  [25] backports_1.2.1        assertthat_0.2.1       Matrix_1.3-2          
##  [28] fastmap_1.1.0          cli_2.3.1              later_1.1.0.1         
##  [31] htmltools_0.5.1.1      tools_4.0.3            gtable_0.3.0          
##  [34] glue_1.4.2             GenomeInfoDbData_1.2.4 fastmatch_1.1-0       
##  [37] Rcpp_1.0.6             cellranger_1.1.0       jquerylib_0.1.3       
##  [40] vctrs_0.3.6            polylabelr_0.2.0       xfun_0.22             
##  [43] ps_1.6.0               testthat_3.0.2         rvest_1.0.0           
##  [46] mime_0.10              lifecycle_1.0.0        XML_3.99-0.6          
##  [49] zlibbioc_1.36.0        scales_1.1.1           promises_1.2.0.1      
##  [52] hms_1.0.0              RColorBrewer_1.1-2     yaml_2.2.1            
##  [55] memoise_2.0.0          gridExtra_2.3          sass_0.3.1            
##  [58] reshape_0.8.8          stringi_1.5.3          RSQLite_2.2.4         
##  [61] highr_0.8              genefilter_1.72.0      desc_1.3.0            
##  [64] caTools_1.18.1         BiocParallel_1.24.1    rlang_0.4.10          
##  [67] pkgconfig_2.0.3        bitops_1.0-6           evaluate_0.14         
##  [70] lattice_0.20-41        labeling_0.4.2         htmlwidgets_1.5.3     
##  [73] bit_4.0.4              tidyselect_1.1.0       plyr_1.8.6            
##  [76] magrittr_2.0.1         R6_2.5.0               generics_0.1.0        
##  [79] DelayedArray_0.16.0    DBI_1.1.1              pillar_1.5.1          
##  [82] haven_2.3.1            withr_2.4.1            survival_3.2-10       
##  [85] RCurl_1.98-1.3         modelr_0.1.8           crayon_1.4.1          
##  [88] KernSmooth_2.23-18     utf8_1.2.1             rmarkdown_2.7         
##  [91] locfit_1.5-9.4         grid_4.0.3             readxl_1.3.1          
##  [94] data.table_1.14.0      blob_1.2.1             reprex_1.0.0          
##  [97] digest_0.6.27          xtable_1.8-4           httpuv_1.5.5          
## [100] munsell_0.5.0          bslib_0.2.4

END of report