Mitch Report

date generated: 2021-04-20

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

##                   x
## A1BG      2.6192564
## A1BG-AS1  0.5230655
## A1CF      0.5526173
## A2M      -3.3389616
## A2M-AS1  -3.1580711
## A2ML1    -0.3535245

Here are some metrics about the input data profile:

Profile metrics

	Profile metrics
num_genesets	2408
num_genes_in_profile	21907
duplicated_genes_present	0
num_profile_genes_in_sets	8450
num_profile_genes_not_in_sets	13457

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt

Gene sets metrics

	Gene sets metrics
num_genesets	2408
num_genesets_excluded	1042
num_genesets_included	1366

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 100 gene sets

set	setSize	pANOVA	s.dist	p.adjustANOVA
Neutrophil degranulation	457	0.00e+00	0.5870	2.00e-100
Innate Immune System	967	5.85e-84	0.3670	3.99e-81
Immune System	1893	3.24e-46	0.1980	1.48e-43
Membrane Trafficking	559	5.33e-36	0.3090	1.82e-33
Vesicle-mediated transport	650	1.64e-31	0.2680	4.49e-29
Signal Transduction	1894	7.04e-28	0.1520	1.60e-25
Hemostasis	549	9.70e-23	0.2450	1.89e-20
Metabolism	1772	1.65e-22	0.1400	2.81e-20
Platelet activation, signaling and aggregation	221	1.35e-20	0.3630	2.05e-18
Signaling by Receptor Tyrosine Kinases	414	1.68e-20	0.2660	2.29e-18
Signaling by Interleukins	386	1.71e-19	0.2680	2.12e-17
Metabolism of proteins	1718	2.21e-19	0.1310	2.52e-17
Post-translational protein modification	1193	6.81e-19	0.1520	7.16e-17
Response to elevated platelet cytosolic Ca2+	110	1.25e-16	0.4570	1.22e-14
Platelet degranulation	106	5.81e-16	0.4550	5.29e-14
Toll-like Receptor Cascades	143	2.29e-15	0.3840	1.96e-13
Disease	1355	2.72e-15	0.1280	2.18e-13
Asparagine N-linked glycosylation	269	5.32e-15	0.2770	4.03e-13
Metabolism of lipids	626	6.70e-15	0.1820	4.81e-13
Transport of small molecules	561	1.57e-14	0.1900	1.07e-12
Toll Like Receptor 4 (TLR4) Cascade	121	3.21e-14	0.3990	2.09e-12
rRNA processing	219	2.40e-13	-0.2870	1.49e-11
ER to Golgi Anterograde Transport	129	2.87e-13	0.3720	1.53e-11
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	92	3.03e-13	0.4400	1.53e-11
Toll Like Receptor 2 (TLR2) Cascade	92	3.03e-13	0.4400	1.53e-11
Toll Like Receptor TLR1:TLR2 Cascade	92	3.03e-13	0.4400	1.53e-11
Toll Like Receptor TLR6:TLR2 Cascade	92	3.03e-13	0.4400	1.53e-11
rRNA processing in the nucleus and cytosol	190	3.58e-13	-0.3060	1.75e-11
Signaling by NOTCH	183	3.84e-13	0.3110	1.81e-11
Interleukin-1 signaling	98	5.37e-13	0.4220	2.45e-11
Diseases of signal transduction by growth factor receptors and second messengers	342	6.05e-13	0.2260	2.67e-11
Major pathway of rRNA processing in the nucleolus and cytosol	180	1.68e-12	-0.3050	7.18e-11
Clathrin-mediated endocytosis	127	3.15e-12	0.3580	1.30e-10
Signaling by Rho GTPases	367	4.57e-12	0.2100	1.84e-10
Interleukin-1 family signaling	125	8.55e-12	0.3530	3.34e-10
Signaling by NTRKs	116	9.74e-12	0.3660	3.69e-10
Transport to the Golgi and subsequent modification	155	1.60e-11	0.3130	5.89e-10
Antigen processing-Cross presentation	98	1.88e-11	0.3920	6.76e-10
RHO GTPase Effectors	250	2.78e-11	0.2440	9.74e-10
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	87	3.99e-11	0.4090	1.36e-09
Toll Like Receptor 7/8 (TLR7/8) Cascade	89	4.41e-11	0.4040	1.47e-09
MyD88 dependent cascade initiated on endosome	88	1.16e-10	0.3970	3.77e-09
Programmed Cell Death	180	1.26e-10	0.2780	3.99e-09
Signaling by NTRK1 (TRKA)	101	1.31e-10	0.3700	4.07e-09
Toll Like Receptor 9 (TLR9) Cascade	92	2.03e-10	0.3830	6.16e-09
Translocation of ZAP-70 to Immunological synapse	24	2.81e-10	-0.7440	8.34e-09
RHO GTPases Activate WASPs and WAVEs	35	4.57e-10	0.6090	1.33e-08
Intra-Golgi and retrograde Golgi-to-ER traffic	179	5.04e-10	0.2690	1.39e-08
Gene expression (Transcription)	1332	5.27e-10	-0.1010	1.39e-08
MyD88 cascade initiated on plasma membrane	82	5.31e-10	0.3970	1.39e-08
Toll Like Receptor 10 (TLR10) Cascade	82	5.31e-10	0.3970	1.39e-08
Toll Like Receptor 5 (TLR5) Cascade	82	5.31e-10	0.3970	1.39e-08
Developmental Biology	732	1.07e-09	0.1320	2.75e-08
Golgi-to-ER retrograde transport	111	1.79e-09	0.3300	4.53e-08
COPI-mediated anterograde transport	78	1.90e-09	0.3930	4.72e-08
Autophagy	124	2.12e-09	0.3110	5.17e-08
Apoptosis	168	2.16e-09	0.2680	5.17e-08
EPH-Ephrin signaling	79	2.31e-09	0.3890	5.45e-08
Amyloid fiber formation	51	2.44e-09	0.4830	5.64e-08
Signaling by WNT	254	4.05e-09	0.2140	9.22e-08
RHO GTPases activate PKNs	48	6.95e-09	0.4830	1.56e-07
MyD88-independent TLR4 cascade	96	7.99e-09	0.3410	1.73e-07
TRIF(TICAM1)-mediated TLR4 signaling	96	7.99e-09	0.3410	1.73e-07
ROS and RNS production in phagocytes	31	8.23e-09	0.5980	1.76e-07
Infectious disease	777	1.03e-08	0.1210	2.18e-07
Generic Transcription Pathway	1085	1.09e-08	-0.1030	2.25e-07
Cellular responses to external stimuli	506	1.91e-08	0.1460	3.89e-07
COPI-independent Golgi-to-ER retrograde traffic	33	2.11e-08	0.5630	4.24e-07
ER-Phagosome pathway	83	2.17e-08	0.3550	4.30e-07
Class I MHC mediated antigen processing & presentation	350	2.99e-08	0.1720	5.84e-07
Cellular response to hypoxia	72	3.43e-08	0.3760	6.61e-07
Detoxification of Reactive Oxygen Species	32	3.64e-08	0.5620	6.90e-07
Cargo recognition for clathrin-mediated endocytosis	90	4.34e-08	0.3340	8.11e-07
Signaling by Nuclear Receptors	217	5.11e-08	0.2150	9.42e-07
COPII-mediated vesicle transport	65	5.29e-08	0.3900	9.56e-07
RUNX1 regulates transcription of genes involved in differentiation of HSCs	83	5.32e-08	0.3450	9.56e-07
Cellular responses to stress	500	5.60e-08	0.1420	9.82e-07
The citric acid (TCA) cycle and respiratory electron transport	172	5.61e-08	0.2400	9.82e-07
trans-Golgi Network Vesicle Budding	69	9.29e-08	0.3720	1.61e-06
ESR-mediated signaling	161	1.07e-07	0.2430	1.83e-06
PD-1 signaling	28	1.11e-07	-0.5790	1.87e-06
rRNA modification in the nucleus and cytosol	59	1.39e-07	-0.3960	2.32e-06
RAB GEFs exchange GTP for GDP on RABs	88	1.51e-07	0.3240	2.49e-06
Rab regulation of trafficking	121	1.59e-07	0.2760	2.59e-06
MAP2K and MAPK activation	34	1.81e-07	0.5170	2.91e-06
tRNA processing	136	2.88e-07	-0.2550	4.58e-06
Post-translational protein phosphorylation	70	2.94e-07	0.3540	4.62e-06
CLEC7A (Dectin-1) signaling	97	3.16e-07	0.3000	4.91e-06
DNA strand elongation	32	3.21e-07	-0.5220	4.92e-06
Signaling by BRAF and RAF fusions	57	3.30e-07	0.3910	4.99e-06
Intracellular signaling by second messengers	273	3.32e-07	0.1790	4.99e-06
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	124	3.67e-07	0.2640	5.45e-06
C-type lectin receptors (CLRs)	129	3.78e-07	0.2590	5.55e-06
RNA Polymerase II Transcription	1204	4.09e-07	-0.0867	5.95e-06
VEGFA-VEGFR2 Pathway	92	4.27e-07	0.3050	6.14e-06
MAP kinase activation	63	4.52e-07	0.3670	6.44e-06
PIP3 activates AKT signaling	241	6.02e-07	0.1870	8.47e-06
Toll Like Receptor 3 (TLR3) Cascade	92	6.70e-07	0.3000	9.34e-06
Signaling by NOTCH4	79	6.95e-07	0.3230	9.58e-06
Signaling by MET	61	7.13e-07	0.3670	9.74e-06

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
Neutrophil degranulation	457	0.00e+00	5.87e-01	2.00e-100
Innate Immune System	967	5.85e-84	3.67e-01	3.99e-81
Immune System	1893	3.24e-46	1.98e-01	1.48e-43
Membrane Trafficking	559	5.33e-36	3.09e-01	1.82e-33
Vesicle-mediated transport	650	1.64e-31	2.68e-01	4.49e-29
Signal Transduction	1894	7.04e-28	1.52e-01	1.60e-25
Hemostasis	549	9.70e-23	2.45e-01	1.89e-20
Metabolism	1772	1.65e-22	1.40e-01	2.81e-20
Platelet activation, signaling and aggregation	221	1.35e-20	3.63e-01	2.05e-18
Signaling by Receptor Tyrosine Kinases	414	1.68e-20	2.66e-01	2.29e-18
Signaling by Interleukins	386	1.71e-19	2.68e-01	2.12e-17
Metabolism of proteins	1718	2.21e-19	1.31e-01	2.52e-17
Post-translational protein modification	1193	6.81e-19	1.52e-01	7.16e-17
Response to elevated platelet cytosolic Ca2+	110	1.25e-16	4.57e-01	1.22e-14
Platelet degranulation	106	5.81e-16	4.55e-01	5.29e-14
Toll-like Receptor Cascades	143	2.29e-15	3.84e-01	1.96e-13
Disease	1355	2.72e-15	1.28e-01	2.18e-13
Asparagine N-linked glycosylation	269	5.32e-15	2.77e-01	4.03e-13
Metabolism of lipids	626	6.70e-15	1.82e-01	4.81e-13
Transport of small molecules	561	1.57e-14	1.90e-01	1.07e-12
Toll Like Receptor 4 (TLR4) Cascade	121	3.21e-14	3.99e-01	2.09e-12
rRNA processing	219	2.40e-13	-2.87e-01	1.49e-11
ER to Golgi Anterograde Transport	129	2.87e-13	3.72e-01	1.53e-11
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	92	3.03e-13	4.40e-01	1.53e-11
Toll Like Receptor 2 (TLR2) Cascade	92	3.03e-13	4.40e-01	1.53e-11
Toll Like Receptor TLR1:TLR2 Cascade	92	3.03e-13	4.40e-01	1.53e-11
Toll Like Receptor TLR6:TLR2 Cascade	92	3.03e-13	4.40e-01	1.53e-11
rRNA processing in the nucleus and cytosol	190	3.58e-13	-3.06e-01	1.75e-11
Signaling by NOTCH	183	3.84e-13	3.11e-01	1.81e-11
Interleukin-1 signaling	98	5.37e-13	4.22e-01	2.45e-11
Diseases of signal transduction by growth factor receptors and second messengers	342	6.05e-13	2.26e-01	2.67e-11
Major pathway of rRNA processing in the nucleolus and cytosol	180	1.68e-12	-3.05e-01	7.18e-11
Clathrin-mediated endocytosis	127	3.15e-12	3.58e-01	1.30e-10
Signaling by Rho GTPases	367	4.57e-12	2.10e-01	1.84e-10
Interleukin-1 family signaling	125	8.55e-12	3.53e-01	3.34e-10
Signaling by NTRKs	116	9.74e-12	3.66e-01	3.69e-10
Transport to the Golgi and subsequent modification	155	1.60e-11	3.13e-01	5.89e-10
Antigen processing-Cross presentation	98	1.88e-11	3.92e-01	6.76e-10
RHO GTPase Effectors	250	2.78e-11	2.44e-01	9.74e-10
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	87	3.99e-11	4.09e-01	1.36e-09
Toll Like Receptor 7/8 (TLR7/8) Cascade	89	4.41e-11	4.04e-01	1.47e-09
MyD88 dependent cascade initiated on endosome	88	1.16e-10	3.97e-01	3.77e-09
Programmed Cell Death	180	1.26e-10	2.78e-01	3.99e-09
Signaling by NTRK1 (TRKA)	101	1.31e-10	3.70e-01	4.07e-09
Toll Like Receptor 9 (TLR9) Cascade	92	2.03e-10	3.83e-01	6.16e-09
Translocation of ZAP-70 to Immunological synapse	24	2.81e-10	-7.44e-01	8.34e-09
RHO GTPases Activate WASPs and WAVEs	35	4.57e-10	6.09e-01	1.33e-08
Intra-Golgi and retrograde Golgi-to-ER traffic	179	5.04e-10	2.69e-01	1.39e-08
Gene expression (Transcription)	1332	5.27e-10	-1.01e-01	1.39e-08
MyD88 cascade initiated on plasma membrane	82	5.31e-10	3.97e-01	1.39e-08
Toll Like Receptor 10 (TLR10) Cascade	82	5.31e-10	3.97e-01	1.39e-08
Toll Like Receptor 5 (TLR5) Cascade	82	5.31e-10	3.97e-01	1.39e-08
Developmental Biology	732	1.07e-09	1.32e-01	2.75e-08
Golgi-to-ER retrograde transport	111	1.79e-09	3.30e-01	4.53e-08
COPI-mediated anterograde transport	78	1.90e-09	3.93e-01	4.72e-08
Autophagy	124	2.12e-09	3.11e-01	5.17e-08
Apoptosis	168	2.16e-09	2.68e-01	5.17e-08
EPH-Ephrin signaling	79	2.31e-09	3.89e-01	5.45e-08
Amyloid fiber formation	51	2.44e-09	4.83e-01	5.64e-08
Signaling by WNT	254	4.05e-09	2.14e-01	9.22e-08
RHO GTPases activate PKNs	48	6.95e-09	4.83e-01	1.56e-07
MyD88-independent TLR4 cascade	96	7.99e-09	3.41e-01	1.73e-07
TRIF(TICAM1)-mediated TLR4 signaling	96	7.99e-09	3.41e-01	1.73e-07
ROS and RNS production in phagocytes	31	8.23e-09	5.98e-01	1.76e-07
Infectious disease	777	1.03e-08	1.21e-01	2.18e-07
Generic Transcription Pathway	1085	1.09e-08	-1.03e-01	2.25e-07
Cellular responses to external stimuli	506	1.91e-08	1.46e-01	3.89e-07
COPI-independent Golgi-to-ER retrograde traffic	33	2.11e-08	5.63e-01	4.24e-07
ER-Phagosome pathway	83	2.17e-08	3.55e-01	4.30e-07
Class I MHC mediated antigen processing & presentation	350	2.99e-08	1.72e-01	5.84e-07
Cellular response to hypoxia	72	3.43e-08	3.76e-01	6.61e-07
Detoxification of Reactive Oxygen Species	32	3.64e-08	5.62e-01	6.90e-07
Cargo recognition for clathrin-mediated endocytosis	90	4.34e-08	3.34e-01	8.11e-07
Signaling by Nuclear Receptors	217	5.11e-08	2.15e-01	9.42e-07
COPII-mediated vesicle transport	65	5.29e-08	3.90e-01	9.56e-07
RUNX1 regulates transcription of genes involved in differentiation of HSCs	83	5.32e-08	3.45e-01	9.56e-07
Cellular responses to stress	500	5.60e-08	1.42e-01	9.82e-07
The citric acid (TCA) cycle and respiratory electron transport	172	5.61e-08	2.40e-01	9.82e-07
trans-Golgi Network Vesicle Budding	69	9.29e-08	3.72e-01	1.61e-06
ESR-mediated signaling	161	1.07e-07	2.43e-01	1.83e-06
PD-1 signaling	28	1.11e-07	-5.79e-01	1.87e-06
rRNA modification in the nucleus and cytosol	59	1.39e-07	-3.96e-01	2.32e-06
RAB GEFs exchange GTP for GDP on RABs	88	1.51e-07	3.24e-01	2.49e-06
Rab regulation of trafficking	121	1.59e-07	2.76e-01	2.59e-06
MAP2K and MAPK activation	34	1.81e-07	5.17e-01	2.91e-06
tRNA processing	136	2.88e-07	-2.55e-01	4.58e-06
Post-translational protein phosphorylation	70	2.94e-07	3.54e-01	4.62e-06
CLEC7A (Dectin-1) signaling	97	3.16e-07	3.00e-01	4.91e-06
DNA strand elongation	32	3.21e-07	-5.22e-01	4.92e-06
Signaling by BRAF and RAF fusions	57	3.30e-07	3.91e-01	4.99e-06
Intracellular signaling by second messengers	273	3.32e-07	1.79e-01	4.99e-06
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	124	3.67e-07	2.64e-01	5.45e-06
C-type lectin receptors (CLRs)	129	3.78e-07	2.59e-01	5.55e-06
RNA Polymerase II Transcription	1204	4.09e-07	-8.67e-02	5.95e-06
VEGFA-VEGFR2 Pathway	92	4.27e-07	3.05e-01	6.14e-06
MAP kinase activation	63	4.52e-07	3.67e-01	6.44e-06
PIP3 activates AKT signaling	241	6.02e-07	1.87e-01	8.47e-06
Toll Like Receptor 3 (TLR3) Cascade	92	6.70e-07	3.00e-01	9.34e-06
Signaling by NOTCH4	79	6.95e-07	3.23e-01	9.58e-06
Signaling by MET	61	7.13e-07	3.67e-01	9.74e-06
Generation of second messenger molecules	38	7.20e-07	-4.64e-01	9.74e-06
Cargo concentration in the ER	30	7.76e-07	5.21e-01	1.03e-05
Oncogenic MAPK signaling	73	7.76e-07	3.34e-01	1.03e-05
Macroautophagy	110	7.88e-07	2.72e-01	1.03e-05
EPHB-mediated forward signaling	32	7.98e-07	5.04e-01	1.03e-05
Cytokine Signaling in Immune system	736	8.01e-07	1.07e-01	1.03e-05
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	65	8.07e-07	3.54e-01	1.03e-05
IRAK4 deficiency (TLR2/4)	10	8.37e-07	8.99e-01	1.05e-05
MyD88 deficiency (TLR2/4)	10	8.37e-07	8.99e-01	1.05e-05
Transcriptional regulation of granulopoiesis	46	8.63e-07	4.19e-01	1.07e-05
Selenocysteine synthesis	92	8.72e-07	-2.97e-01	1.07e-05
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	80	9.74e-07	3.17e-01	1.19e-05
Pre-NOTCH Expression and Processing	65	1.18e-06	3.48e-01	1.43e-05
Endosomal Sorting Complex Required For Transport (ESCRT)	29	1.25e-06	5.20e-01	1.49e-05
L1CAM interactions	85	1.26e-06	3.04e-01	1.49e-05
Phosphorylation of CD3 and TCR zeta chains	27	1.38e-06	-5.37e-01	1.62e-05
Interleukin-17 signaling	68	1.45e-06	3.38e-01	1.69e-05
RAB geranylgeranylation	61	1.46e-06	3.57e-01	1.69e-05
Signaling by high-kinase activity BRAF mutants	31	1.54e-06	4.99e-01	1.77e-05
PPARA activates gene expression	104	1.84e-06	2.71e-01	2.09e-05
PCP/CE pathway	87	1.87e-06	2.96e-01	2.10e-05
Smooth Muscle Contraction	31	1.87e-06	4.95e-01	2.10e-05
Signaling by RAF1 mutants	34	1.94e-06	4.72e-01	2.16e-05
Extracellular matrix organization	219	2.25e-06	1.85e-01	2.48e-05
Golgi Associated Vesicle Biogenesis	55	2.33e-06	3.68e-01	2.55e-05
Activation of the pre-replicative complex	32	2.43e-06	-4.81e-01	2.63e-05
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism	12	2.46e-06	7.85e-01	2.63e-05
alpha-linolenic acid (ALA) metabolism	12	2.46e-06	7.85e-01	2.63e-05
Hh mutants that don’t undergo autocatalytic processing are degraded by ERAD	54	2.48e-06	3.70e-01	2.63e-05
Defective CFTR causes cystic fibrosis	60	2.57e-06	3.51e-01	2.71e-05
Iron uptake and transport	52	2.62e-06	3.77e-01	2.72e-05
MAPK family signaling cascades	270	2.63e-06	1.66e-01	2.72e-05
Protein ubiquitination	72	3.07e-06	3.18e-01	3.15e-05
TCF dependent signaling in response to WNT	166	3.21e-06	2.09e-01	3.27e-05
Signaling by VEGF	100	3.27e-06	2.69e-01	3.28e-05
Regulation of PTEN stability and activity	67	3.28e-06	3.29e-01	3.28e-05
RNA Polymerase I Promoter Opening	19	3.29e-06	6.16e-01	3.28e-05
Budding and maturation of HIV virion	26	3.45e-06	5.26e-01	3.41e-05
Respiratory electron transport	101	3.58e-06	2.67e-01	3.52e-05
Interleukin-4 and Interleukin-13 signaling	92	3.68e-06	2.79e-01	3.59e-05
Deubiquitination	242	3.70e-06	1.73e-01	3.59e-05
Integration of energy metabolism	86	3.84e-06	2.88e-01	3.65e-05
Paradoxical activation of RAF signaling by kinase inactive BRAF	38	3.90e-06	4.33e-01	3.65e-05
Signaling by RAS mutants	38	3.90e-06	4.33e-01	3.65e-05
Signaling by moderate kinase activity BRAF mutants	38	3.90e-06	4.33e-01	3.65e-05
Signaling downstream of RAS mutants	38	3.90e-06	4.33e-01	3.65e-05
Regulation of mRNA stability by proteins that bind AU-rich elements	88	3.93e-06	2.85e-01	3.65e-05
Beta-catenin independent WNT signaling	137	4.52e-06	2.27e-01	4.17e-05
Antimicrobial peptides	33	4.93e-06	4.59e-01	4.52e-05
Regulation of lipid metabolism by PPARalpha	106	5.54e-06	2.55e-01	5.04e-05
Cross-presentation of soluble exogenous antigens (endosomes)	48	5.62e-06	3.79e-01	5.08e-05
Hedgehog ligand biogenesis	59	5.69e-06	3.41e-01	5.11e-05
Peptide chain elongation	88	5.95e-06	-2.79e-01	5.31e-05
Insulin receptor recycling	21	6.43e-06	5.69e-01	5.70e-05
Eukaryotic Translation Elongation	93	6.47e-06	-2.71e-01	5.70e-05
Regulation of ornithine decarboxylase (ODC)	50	6.72e-06	3.68e-01	5.89e-05
Hh mutants abrogate ligand secretion	55	6.85e-06	3.51e-01	5.96e-05
Transferrin endocytosis and recycling	26	6.92e-06	5.09e-01	5.98e-05
Negative regulation of NOTCH4 signaling	54	7.02e-06	3.53e-01	6.03e-05
Influenza Viral RNA Transcription and Replication	135	7.53e-06	-2.23e-01	6.43e-05
ABC transporter disorders	71	7.90e-06	3.07e-01	6.70e-05
MAPK1/MAPK3 signaling	236	8.18e-06	1.69e-01	6.90e-05
Activation of ATR in response to replication stress	37	8.43e-06	-4.23e-01	7.06e-05
AUF1 (hnRNP D0) binds and destabilizes mRNA	54	8.71e-06	3.50e-01	7.23e-05
Diseases associated with the TLR signaling cascade	23	8.79e-06	5.35e-01	7.23e-05
Diseases of Immune System	23	8.79e-06	5.35e-01	7.23e-05
Hyaluronan uptake and degradation	12	8.85e-06	7.41e-01	7.24e-05
RHO GTPases Activate NADPH Oxidases	21	9.01e-06	5.60e-01	7.33e-05
Degradation of DVL	55	1.03e-05	3.44e-01	8.34e-05
Metabolism of carbohydrates	244	1.10e-05	1.63e-01	8.84e-05
Phospholipid metabolism	185	1.23e-05	1.86e-01	9.85e-05
Platelet Aggregation (Plug Formation)	28	1.27e-05	4.77e-01	1.00e-04
FLT3 Signaling	245	1.28e-05	1.62e-01	1.00e-04
Degradation of GLI2 by the proteasome	57	1.28e-05	3.34e-01	1.00e-04
Axon guidance	457	1.28e-05	1.19e-01	1.00e-04
PTEN Regulation	139	1.30e-05	2.14e-01	1.01e-04
Eukaryotic Translation Termination	92	1.32e-05	-2.63e-01	1.02e-04
Regulation of activated PAK-2p34 by proteasome mediated degradation	49	1.37e-05	3.59e-01	1.05e-04
Degradation of GLI1 by the proteasome	58	1.42e-05	3.29e-01	1.08e-04
Opioid Signalling	75	1.55e-05	2.89e-01	1.17e-04
Vif-mediated degradation of APOBEC3G	53	1.73e-05	3.41e-01	1.31e-04
Regulation of TLR by endogenous ligand	11	1.93e-05	7.44e-01	1.45e-04
Pre-NOTCH Transcription and Translation	49	1.95e-05	3.53e-01	1.46e-04
NIK–>noncanonical NF-kB signaling	58	1.99e-05	3.24e-01	1.47e-04
HDACs deacetylate histones	47	2.04e-05	3.59e-01	1.51e-04
Regulation of Apoptosis	52	2.18e-05	3.40e-01	1.60e-04
Nervous system development	476	2.40e-05	1.13e-01	1.75e-04
Dectin-1 mediated noncanonical NF-kB signaling	59	2.42e-05	3.18e-01	1.76e-04
Viral mRNA Translation	88	2.47e-05	-2.60e-01	1.79e-04
Senescence-Associated Secretory Phenotype (SASP)	66	2.52e-05	3.00e-01	1.81e-04
The role of GTSE1 in G2/M progression after G2 checkpoint	59	2.58e-05	3.17e-01	1.85e-04
HSP90 chaperone cycle for steroid hormone receptors (SHR)	36	2.62e-05	4.05e-01	1.86e-04
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	53	2.62e-05	3.34e-01	1.86e-04
GLI3 is processed to GLI3R by the proteasome	58	2.78e-05	3.18e-01	1.96e-04
Glycerophospholipid biosynthesis	106	2.89e-05	2.35e-01	2.02e-04
Selenoamino acid metabolism	114	2.96e-05	-2.26e-01	2.06e-04
MAPK6/MAPK4 signaling	83	3.05e-05	2.65e-01	2.11e-04
RAF/MAP kinase cascade	231	3.18e-05	1.59e-01	2.20e-04
Oxidative Stress Induced Senescence	79	3.24e-05	2.70e-01	2.22e-04
EGFR downregulation	27	3.34e-05	4.61e-01	2.28e-04
Metabolism of polyamines	58	3.35e-05	3.15e-01	2.28e-04
Activation of NF-kappaB in B cells	66	3.57e-05	2.94e-01	2.41e-04
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer’s disease models	21	4.10e-05	5.17e-01	2.74e-04
Neurodegenerative Diseases	21	4.10e-05	5.17e-01	2.74e-04
Neddylation	219	4.38e-05	1.60e-01	2.92e-04
Translocation of SLC2A4 (GLUT4) to the plasma membrane	48	4.45e-05	3.41e-01	2.95e-04
SARS-CoV Infections	140	4.53e-05	2.00e-01	2.99e-04
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	94	4.84e-05	-2.42e-01	3.18e-04
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	51	4.97e-05	3.28e-01	3.22e-04
p53-Independent DNA Damage Response	51	4.97e-05	3.28e-01	3.22e-04
p53-Independent G1/S DNA damage checkpoint	51	4.97e-05	3.28e-01	3.22e-04
Leishmania infection	245	5.06e-05	1.50e-01	3.26e-04
Nuclear Events (kinase and transcription factor activation)	53	5.25e-05	3.21e-01	3.37e-04
Signal amplification	28	5.41e-05	4.41e-01	3.45e-04
E3 ubiquitin ligases ubiquitinate target proteins	52	5.50e-05	3.23e-01	3.50e-04
Ub-specific processing proteases	171	5.65e-05	1.78e-01	3.57e-04
Late endosomal microautophagy	30	6.00e-05	4.23e-01	3.78e-04
Vpu mediated degradation of CD4	51	6.08e-05	3.25e-01	3.81e-04
MTOR signalling	39	6.11e-05	3.71e-01	3.81e-04
DNA methylation	20	6.16e-05	5.17e-01	3.82e-04
Degradation of beta-catenin by the destruction complex	84	6.67e-05	2.52e-01	4.12e-04
Cellular Senescence	144	6.80e-05	1.92e-01	4.19e-04
RHO GTPases Activate ROCKs	18	6.85e-05	5.42e-01	4.20e-04
Infection with Mycobacterium tuberculosis	26	7.20e-05	4.50e-01	4.39e-04
Lysosome Vesicle Biogenesis	32	7.32e-05	4.05e-01	4.44e-04
Homologous DNA Pairing and Strand Exchange	42	7.63e-05	-3.53e-01	4.61e-04
Metabolism of RNA	688	7.82e-05	-8.83e-02	4.70e-04
Regulation of RUNX3 expression and activity	55	8.07e-05	3.07e-01	4.84e-04
Signaling by EGFR	46	8.37e-05	3.35e-01	4.98e-04
Signaling by Insulin receptor	59	8.38e-05	2.96e-01	4.98e-04
Signalling to ERKs	32	8.47e-05	4.01e-01	5.01e-04
Erythrocytes take up carbon dioxide and release oxygen	11	9.46e-05	6.80e-01	5.53e-04
O2/CO2 exchange in erythrocytes	11	9.46e-05	6.80e-01	5.53e-04
Advanced glycosylation endproduct receptor signaling	12	9.48e-05	6.51e-01	5.53e-04
Telomere C-strand (Lagging Strand) Synthesis	34	9.64e-05	-3.86e-01	5.60e-04
Ubiquitin-dependent degradation of Cyclin D	51	1.02e-04	3.15e-01	5.88e-04
Hedgehog ‘on’ state	76	1.08e-04	2.57e-01	6.23e-04
Negative regulation of MET activity	18	1.11e-04	5.26e-01	6.39e-04
Uptake and function of anthrax toxins	10	1.14e-04	7.05e-01	6.52e-04
tRNA processing in the nucleus	59	1.15e-04	-2.90e-01	6.52e-04
Amino acids regulate mTORC1	50	1.16e-04	3.15e-01	6.57e-04
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	11	1.17e-04	6.71e-01	6.58e-04
Ion channel transport	135	1.22e-04	1.92e-01	6.84e-04
Influenza Infection	154	1.22e-04	-1.79e-01	6.84e-04
Extension of Telomeres	51	1.26e-04	-3.10e-01	7.00e-04
Platelet sensitization by LDL	16	1.28e-04	5.53e-01	7.08e-04
Autodegradation of Cdh1 by Cdh1:APC/C	64	1.28e-04	2.77e-01	7.08e-04
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	22	1.29e-04	4.72e-01	7.08e-04
Unwinding of DNA	12	1.32e-04	-6.37e-01	7.22e-04
p130Cas linkage to MAPK signaling for integrins	11	1.32e-04	6.65e-01	7.22e-04
Estrogen-dependent gene expression	99	1.33e-04	2.22e-01	7.22e-04
Transcriptional regulation of white adipocyte differentiation	77	1.36e-04	2.51e-01	7.37e-04
Signaling by NOTCH1	67	1.37e-04	2.69e-01	7.37e-04
Response of EIF2AK4 (GCN2) to amino acid deficiency	100	1.46e-04	-2.20e-01	7.84e-04
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	24	1.57e-04	-4.46e-01	8.44e-04
ABC-family proteins mediated transport	94	1.66e-04	2.25e-01	8.84e-04
Recycling pathway of L1	26	1.68e-04	4.26e-01	8.92e-04
RHO GTPases activate PAKs	20	1.70e-04	4.86e-01	9.02e-04
Platelet homeostasis	69	1.71e-04	2.62e-01	9.02e-04
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	73	1.73e-04	2.54e-01	9.11e-04
Notch-HLH transcription pathway	28	1.86e-04	4.08e-01	9.71e-04
Sealing of the nuclear envelope (NE) by ESCRT-III	25	1.86e-04	4.32e-01	9.72e-04
Response of Mtb to phagocytosis	22	1.91e-04	4.59e-01	9.90e-04
Integrin signaling	22	2.08e-04	4.57e-01	1.08e-03
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	30	2.11e-04	3.91e-01	1.09e-03
Hyaluronan metabolism	15	2.20e-04	5.51e-01	1.13e-03
Interferon alpha/beta signaling	57	2.25e-04	-2.82e-01	1.15e-03
SARS-CoV-2 Infection	63	2.35e-04	2.68e-01	1.20e-03
Fanconi Anemia Pathway	36	2.43e-04	-3.53e-01	1.24e-03
Resolution of Abasic Sites (AP sites)	37	2.48e-04	-3.48e-01	1.25e-03
Autodegradation of the E3 ubiquitin ligase COP1	50	2.53e-04	2.99e-01	1.27e-03
APC/C:Cdc20 mediated degradation of Securin	67	2.63e-04	2.58e-01	1.32e-03
SCF-beta-TrCP mediated degradation of Emi1	54	2.64e-04	2.87e-01	1.32e-03
Chaperonin-mediated protein folding	84	2.68e-04	2.30e-01	1.34e-03
Sphingolipid metabolism	78	2.72e-04	2.38e-01	1.35e-03
UCH proteinases	87	2.83e-04	2.25e-01	1.40e-03
Downstream signaling events of B Cell Receptor (BCR)	80	2.96e-04	2.34e-01	1.46e-03
Collagen degradation	28	3.05e-04	3.94e-01	1.50e-03
MHC class II antigen presentation	101	3.09e-04	2.08e-01	1.51e-03
RAF activation	32	3.35e-04	3.66e-01	1.64e-03
Metabolism of steroids	120	3.42e-04	1.89e-01	1.66e-03
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	51	3.51e-04	2.89e-01	1.70e-03
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	114	3.56e-04	-1.94e-01	1.71e-03
Nonsense-Mediated Decay (NMD)	114	3.56e-04	-1.94e-01	1.71e-03
Golgi Cisternae Pericentriolar Stack Reorganization	14	3.65e-04	5.50e-01	1.75e-03
TP53 Regulates Metabolic Genes	85	3.76e-04	2.23e-01	1.80e-03
Formation of a pool of free 40S subunits	100	3.77e-04	-2.06e-01	1.80e-03
Interferon Signaling	177	3.85e-04	-1.55e-01	1.82e-03
Presynaptic phase of homologous DNA pairing and strand exchange	39	4.00e-04	-3.28e-01	1.89e-03
Inhibition of DNA recombination at telomere	35	4.21e-04	3.44e-01	1.98e-03
COPI-dependent Golgi-to-ER retrograde traffic	78	4.28e-04	2.31e-01	2.01e-03
G-protein beta:gamma signalling	29	4.44e-04	3.77e-01	2.08e-03
Transcriptional regulation by RUNX1	185	4.54e-04	1.49e-01	2.12e-03
Lagging Strand Synthesis	20	4.63e-04	-4.52e-01	2.15e-03
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	76	4.70e-04	2.32e-01	2.18e-03
Degradation of AXIN	54	4.87e-04	2.74e-01	2.25e-03
GRB2:SOS provides linkage to MAPK signaling for Integrins	12	4.97e-04	5.80e-01	2.29e-03
Energy dependent regulation of mTOR by LKB1-AMPK	27	5.03e-04	3.87e-01	2.31e-03
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases	13	5.15e-04	5.56e-01	2.35e-03
Packaging Of Telomere Ends	20	5.17e-04	4.48e-01	2.35e-03
Stabilization of p53	55	5.37e-04	2.70e-01	2.43e-03
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	73	5.49e-04	2.34e-01	2.48e-03
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	72	5.71e-04	2.35e-01	2.57e-03
activated TAK1 mediates p38 MAPK activation	19	5.78e-04	4.56e-01	2.60e-03
APC/C:Cdc20 mediated degradation of mitotic proteins	75	5.83e-04	2.30e-01	2.60e-03
CDK-mediated phosphorylation and removal of Cdc6	72	5.83e-04	2.34e-01	2.60e-03
Interactions of Rev with host cellular proteins	37	5.97e-04	-3.26e-01	2.65e-03
Rev-mediated nuclear export of HIV RNA	35	6.35e-04	-3.34e-01	2.82e-03
Degradation of the extracellular matrix	78	6.48e-04	2.23e-01	2.86e-03
Protein folding	90	6.57e-04	2.08e-01	2.90e-03
Regulation of RAS by GAPs	67	6.68e-04	2.40e-01	2.93e-03
Dissolution of Fibrin Clot	12	6.70e-04	5.67e-01	2.93e-03
Regulation of insulin secretion	60	6.70e-04	2.54e-01	2.93e-03
Retrograde neurotrophin signalling	12	6.74e-04	5.67e-01	2.93e-03
Signal transduction by L1	20	6.81e-04	4.39e-01	2.95e-03
MAPK targets/ Nuclear events mediated by MAP kinases	31	7.33e-04	3.50e-01	3.17e-03
mTORC1-mediated signalling	24	7.53e-04	3.97e-01	3.25e-03
Transmission across Chemical Synapses	172	7.60e-04	1.49e-01	3.26e-03
TBC/RABGAPs	45	7.61e-04	2.90e-01	3.26e-03
Adaptive Immune System	757	7.74e-04	7.18e-02	3.30e-03
Plasma lipoprotein assembly, remodeling, and clearance	53	8.47e-04	2.65e-01	3.59e-03
PCNA-Dependent Long Patch Base Excision Repair	21	8.48e-04	-4.21e-01	3.59e-03
NS1 Mediated Effects on Host Pathways	40	8.53e-04	-3.05e-01	3.59e-03
Signaling by Non-Receptor Tyrosine Kinases	48	8.53e-04	2.78e-01	3.59e-03
Signaling by PTK6	48	8.53e-04	2.78e-01	3.59e-03
Asymmetric localization of PCP proteins	61	8.66e-04	2.47e-01	3.63e-03
Costimulation by the CD28 family	74	8.86e-04	-2.23e-01	3.70e-03
Factors involved in megakaryocyte development and platelet production	117	8.93e-04	1.78e-01	3.71e-03
ERK/MAPK targets	22	8.93e-04	4.09e-01	3.71e-03
p75 NTR receptor-mediated signalling	89	9.07e-04	2.03e-01	3.76e-03
XBP1(S) activates chaperone genes	47	9.11e-04	2.80e-01	3.76e-03
HIV Infection	225	9.21e-04	1.28e-01	3.79e-03
Semaphorin interactions	57	9.23e-04	2.54e-01	3.79e-03
Extra-nuclear estrogen signaling	66	9.28e-04	2.36e-01	3.79e-03
SCF(Skp2)-mediated degradation of p27/p21	60	9.73e-04	2.46e-01	3.97e-03
Spry regulation of FGF signaling	16	9.96e-04	4.75e-01	4.05e-03
Transcriptional regulation by RUNX3	90	1.01e-03	2.01e-01	4.08e-03
Antigen processing: Ubiquitination & Proteasome degradation	289	1.01e-03	1.12e-01	4.10e-03
Neurotransmitter receptors and postsynaptic signal transmission	124	1.06e-03	1.70e-01	4.26e-03
DARPP-32 events	22	1.08e-03	4.02e-01	4.34e-03
Growth hormone receptor signaling	20	1.10e-03	4.21e-01	4.41e-03
Signaling by Hedgehog	121	1.10e-03	1.72e-01	4.41e-03
IRE1alpha activates chaperones	49	1.13e-03	2.69e-01	4.49e-03
Transcriptional regulation by RUNX2	103	1.14e-03	1.86e-01	4.52e-03
HDR through Homologous Recombination (HRR)	66	1.15e-03	-2.31e-01	4.56e-03
Gap junction trafficking	14	1.16e-03	5.01e-01	4.58e-03
Fatty acid metabolism	153	1.16e-03	1.52e-01	4.58e-03
CDT1 association with the CDC6:ORC:origin complex	58	1.18e-03	2.46e-01	4.64e-03
Neuronal System	259	1.19e-03	1.17e-01	4.67e-03
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	53	1.21e-03	2.57e-01	4.71e-03
Complex I biogenesis	55	1.21e-03	2.52e-01	4.72e-03
Calnexin/calreticulin cycle	26	1.22e-03	3.66e-01	4.75e-03
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	35	1.23e-03	3.16e-01	4.77e-03
ADP signalling through P2Y purinoceptor 1	21	1.25e-03	4.07e-01	4.82e-03
Metabolism of non-coding RNA	53	1.35e-03	-2.54e-01	5.18e-03
snRNP Assembly	53	1.35e-03	-2.54e-01	5.18e-03
Signaling by Erythropoietin	24	1.35e-03	3.78e-01	5.18e-03
Thrombin signalling through proteinase activated receptors (PARs)	27	1.42e-03	3.55e-01	5.41e-03
NOTCH1 Intracellular Domain Regulates Transcription	45	1.45e-03	2.74e-01	5.52e-03
GPVI-mediated activation cascade	31	1.48e-03	3.30e-01	5.63e-03
Regulation of cholesterol biosynthesis by SREBP (SREBF)	55	1.56e-03	2.47e-01	5.89e-03
Rho GTPase cycle	126	1.57e-03	1.63e-01	5.91e-03
GAB1 signalosome	15	1.59e-03	4.71e-01	5.97e-03
InlB-mediated entry of Listeria monocytogenes into host cell	12	1.61e-03	5.26e-01	6.05e-03
NEP/NS2 Interacts with the Cellular Export Machinery	32	1.67e-03	-3.21e-01	6.23e-03
Disorders of transmembrane transporters	148	1.67e-03	1.50e-01	6.23e-03
Formation of ATP by chemiosmotic coupling	18	1.67e-03	4.28e-01	6.23e-03
Regulation of RUNX2 expression and activity	67	1.71e-03	2.22e-01	6.33e-03
Aquaporin-mediated transport	38	1.72e-03	2.94e-01	6.37e-03
Platelet Adhesion to exposed collagen	13	1.76e-03	5.01e-01	6.49e-03
Fc epsilon receptor (FCERI) signaling	191	1.77e-03	1.31e-01	6.51e-03
G1/S DNA Damage Checkpoints	66	1.79e-03	2.22e-01	6.56e-03
Regulation of actin dynamics for phagocytic cup formation	123	1.85e-03	1.62e-01	6.78e-03
Diseases of carbohydrate metabolism	29	1.86e-03	3.34e-01	6.80e-03
Vpr-mediated nuclear import of PICs	34	1.87e-03	-3.08e-01	6.80e-03
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	182	1.89e-03	-1.34e-01	6.83e-03
p53-Dependent G1 DNA Damage Response	64	1.89e-03	2.25e-01	6.83e-03
p53-Dependent G1/S DNA damage checkpoint	64	1.89e-03	2.25e-01	6.83e-03
tRNA modification in the nucleus and cytosol	43	1.92e-03	-2.73e-01	6.90e-03
Inflammasomes	20	1.92e-03	4.01e-01	6.90e-03
Signaling by Leptin	10	1.97e-03	5.65e-01	7.07e-03
Sema4D in semaphorin signaling	22	2.00e-03	3.80e-01	7.17e-03
Nuclear import of Rev protein	34	2.04e-03	-3.06e-01	7.26e-03
PLC beta mediated events	43	2.09e-03	2.71e-01	7.43e-03
Fcgamma receptor (FCGR) dependent phagocytosis	147	2.11e-03	1.47e-01	7.48e-03
Signaling by GPCR	545	2.12e-03	7.69e-02	7.51e-03
The NLRP3 inflammasome	15	2.13e-03	4.58e-01	7.51e-03
VLDLR internalisation and degradation	12	2.16e-03	5.11e-01	7.59e-03
Pentose phosphate pathway	13	2.26e-03	4.89e-01	7.94e-03
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	15	2.30e-03	4.55e-01	8.05e-03
TAK1 activates NFkB by phosphorylation and activation of IKKs complex	27	2.38e-03	3.38e-01	8.30e-03
Pre-NOTCH Processing in Golgi	18	2.51e-03	4.11e-01	8.75e-03
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	54	2.55e-03	2.37e-01	8.78e-03
Constitutive Signaling by NOTCH1 PEST Domain Mutants	54	2.55e-03	2.37e-01	8.78e-03
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	54	2.55e-03	2.37e-01	8.78e-03
Signaling by NOTCH1 PEST Domain Mutants in Cancer	54	2.55e-03	2.37e-01	8.78e-03
Signaling by NOTCH1 in Cancer	54	2.55e-03	2.37e-01	8.78e-03
Glucagon signaling in metabolic regulation	27	2.63e-03	3.34e-01	9.01e-03
GPCR downstream signalling	500	2.69e-03	7.84e-02	9.22e-03
Interactions of Vpr with host cellular proteins	37	2.75e-03	-2.84e-01	9.31e-03
Cleavage of the damaged purine	24	2.75e-03	3.53e-01	9.31e-03
Depurination	24	2.75e-03	3.53e-01	9.31e-03
Recognition and association of DNA glycosylase with site containing an affected purine	24	2.75e-03	3.53e-01	9.31e-03
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	22	2.81e-03	3.68e-01	9.49e-03
Regulation of APC/C activators between G1/S and early anaphase	80	2.83e-03	1.93e-01	9.54e-03
Signaling by TGFB family members	91	2.84e-03	1.81e-01	9.57e-03
Glycogen metabolism	23	2.91e-03	3.59e-01	9.78e-03
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding	29	2.94e-03	3.19e-01	9.83e-03
IKK complex recruitment mediated by RIP1	23	2.99e-03	3.58e-01	9.98e-03
Formation of the cornified envelope	21	3.06e-03	3.73e-01	1.02e-02
Vasopressin regulates renal water homeostasis via Aquaporins	34	3.22e-03	2.92e-01	1.07e-02
Mitotic Anaphase	224	3.35e-03	1.14e-01	1.11e-02
IRAK1 recruits IKK complex	10	3.46e-03	5.34e-01	1.14e-02
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	10	3.46e-03	5.34e-01	1.14e-02
Cell recruitment (pro-inflammatory response)	22	3.47e-03	3.60e-01	1.14e-02
Purinergic signaling in leishmaniasis infection	22	3.47e-03	3.60e-01	1.14e-02
Death Receptor Signalling	132	3.50e-03	1.47e-01	1.15e-02
APC/C-mediated degradation of cell cycle proteins	87	3.52e-03	1.81e-01	1.15e-02
Regulation of mitotic cell cycle	87	3.52e-03	1.81e-01	1.15e-02
HDR through Single Strand Annealing (SSA)	37	3.61e-03	-2.76e-01	1.17e-02
G-protein mediated events	44	3.65e-03	2.53e-01	1.18e-02
MET activates RAP1 and RAC1	10	3.66e-03	5.31e-01	1.19e-02
Thromboxane signalling through TP receptor	20	3.68e-03	3.75e-01	1.19e-02
SARS-CoV-1 Infection	47	3.74e-03	2.44e-01	1.20e-02
Selective autophagy	58	3.80e-03	2.20e-01	1.22e-02
M Phase	360	3.81e-03	8.88e-02	1.22e-02
NOTCH4 Activation and Transmission of Signal to the Nucleus	10	3.85e-03	5.28e-01	1.23e-02
Processive synthesis on the lagging strand	15	3.88e-03	-4.31e-01	1.24e-02
SHC1 events in EGFR signaling	12	3.92e-03	4.81e-01	1.25e-02
G alpha (z) signalling events	36	4.07e-03	2.77e-01	1.29e-02
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS)	12	4.12e-03	4.78e-01	1.30e-02
Diseases of hemostasis	12	4.12e-03	4.78e-01	1.30e-02
Signaling by EGFR in Cancer	23	4.22e-03	3.45e-01	1.33e-02
Antiviral mechanism by IFN-stimulated genes	80	4.28e-03	-1.85e-01	1.35e-02
Signaling by TGF-beta Receptor Complex	72	4.29e-03	1.95e-01	1.35e-02
Signaling by ERBB4	44	4.37e-03	2.48e-01	1.37e-02
Sema4D induced cell migration and growth-cone collapse	19	4.48e-03	3.77e-01	1.40e-02
G alpha (i) signalling events	245	4.53e-03	1.05e-01	1.41e-02
Condensation of Prophase Chromosomes	29	4.54e-03	3.04e-01	1.41e-02
Export of Viral Ribonucleoproteins from Nucleus	33	4.60e-03	-2.85e-01	1.43e-02
Plasma lipoprotein clearance	29	4.75e-03	3.03e-01	1.47e-02
Prolonged ERK activation events	13	4.76e-03	4.52e-01	1.47e-02
Apoptotic execution phase	45	4.77e-03	2.43e-01	1.47e-02
Trafficking of GluR2-containing AMPA receptors	12	4.79e-03	4.70e-01	1.48e-02
Mitotic Metaphase and Anaphase	225	4.82e-03	1.09e-01	1.48e-02
Disassembly of the destruction complex and recruitment of AXIN to the membrane	29	4.82e-03	3.02e-01	1.48e-02
Transport of Ribonucleoproteins into the Host Nucleus	32	4.86e-03	-2.88e-01	1.49e-02
Muscle contraction	136	4.93e-03	1.40e-01	1.50e-02
WNT5A-dependent internalization of FZD4	13	5.02e-03	4.49e-01	1.53e-02
Assembly Of The HIV Virion	15	5.09e-03	4.18e-01	1.54e-02
Diseases of programmed cell death	28	5.10e-03	3.06e-01	1.54e-02
LDL clearance	18	5.19e-03	3.81e-01	1.57e-02
Transport of Mature mRNA Derived from an Intronless Transcript	42	5.36e-03	-2.48e-01	1.61e-02
Cell surface interactions at the vascular wall	174	5.36e-03	1.22e-01	1.61e-02
Membrane binding and targetting of GAG proteins	13	5.40e-03	4.46e-01	1.62e-02
Synthesis And Processing Of GAG, GAGPOL Polyproteins	13	5.40e-03	4.46e-01	1.62e-02
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	36	5.50e-03	2.67e-01	1.64e-02
Cyclin E associated events during G1/S transition	83	5.53e-03	1.76e-01	1.65e-02
AKT phosphorylates targets in the cytosol	14	5.54e-03	4.28e-01	1.65e-02
ADP signalling through P2Y purinoceptor 12	18	5.56e-03	3.77e-01	1.65e-02
Transport of the SLBP independent Mature mRNA	35	5.65e-03	-2.70e-01	1.67e-02
Interleukin-10 signaling	35	5.66e-03	2.70e-01	1.67e-02
Uptake and actions of bacterial toxins	27	5.68e-03	3.07e-01	1.68e-02
Unfolded Protein Response (UPR)	87	5.84e-03	1.71e-01	1.72e-02
Glycosaminoglycan metabolism	94	5.91e-03	1.64e-01	1.74e-02
GRB2 events in EGFR signaling	11	6.02e-03	4.78e-01	1.77e-02
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	11	6.19e-03	4.77e-01	1.81e-02
Intraflagellar transport	39	6.22e-03	-2.53e-01	1.82e-02
Activation of HOX genes during differentiation	69	6.52e-03	1.89e-01	1.89e-02
Activation of anterior HOX genes in hindbrain development during early embryogenesis	69	6.52e-03	1.89e-01	1.89e-02
Transport of bile salts and organic acids, metal ions and amine compounds	55	6.53e-03	2.12e-01	1.89e-02
RHO GTPases activate CIT	18	6.61e-03	3.70e-01	1.91e-02
G-protein activation	23	6.68e-03	3.27e-01	1.93e-02
ERKs are inactivated	13	6.71e-03	4.34e-01	1.93e-02
tRNA Aminoacylation	42	6.78e-03	-2.41e-01	1.95e-02
Stimuli-sensing channels	74	6.87e-03	1.82e-01	1.97e-02
Mitochondrial biogenesis	88	7.05e-03	1.66e-01	2.02e-02
GABA receptor activation	36	7.11e-03	2.59e-01	2.03e-02
Signaling by SCF-KIT	40	7.17e-03	2.46e-01	2.05e-02
Polymerase switching on the C-strand of the telomere	26	7.19e-03	-3.05e-01	2.05e-02
Synthesis of PC	23	7.24e-03	3.23e-01	2.05e-02
Activation of Matrix Metalloproteinases	23	7.33e-03	3.23e-01	2.08e-02
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	80	7.44e-03	1.73e-01	2.10e-02
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	32	7.55e-03	2.73e-01	2.13e-02
Interleukin-12 family signaling	53	7.67e-03	2.12e-01	2.16e-02
Syndecan interactions	19	7.70e-03	3.53e-01	2.17e-02
Gastrin-CREB signalling pathway via PKC and MAPK	14	7.84e-03	4.10e-01	2.20e-02
Activation of gene expression by SREBF (SREBP)	42	7.92e-03	2.37e-01	2.22e-02
TGF-beta receptor signaling activates SMADs	32	7.94e-03	2.71e-01	2.22e-02
ER Quality Control Compartment (ERQC)	21	7.99e-03	3.34e-01	2.23e-02
Erythropoietin activates RAS	13	8.13e-03	4.24e-01	2.26e-02
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	32	8.22e-03	-2.70e-01	2.28e-02
Regulation of Glucokinase by Glucokinase Regulatory Protein	32	8.22e-03	-2.70e-01	2.28e-02
GTP hydrolysis and joining of the 60S ribosomal subunit	111	8.23e-03	-1.45e-01	2.28e-02
Caspase activation via extrinsic apoptotic signalling pathway	25	8.38e-03	3.05e-01	2.31e-02
Glycosphingolipid metabolism	36	8.40e-03	2.54e-01	2.31e-02
Signaling by FGFR3	31	8.41e-03	2.73e-01	2.31e-02
Suppression of phagosomal maturation	12	8.51e-03	4.39e-01	2.34e-02
Negative regulation of FGFR3 signaling	20	8.81e-03	3.38e-01	2.41e-02
Hedgehog ‘off’ state	93	8.83e-03	1.57e-01	2.41e-02
Mucopolysaccharidoses	11	8.83e-03	4.56e-01	2.41e-02
Interleukin-3, Interleukin-5 and GM-CSF signaling	40	8.86e-03	2.39e-01	2.41e-02
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	36	8.91e-03	2.52e-01	2.42e-02
Activation of GABAB receptors	31	8.98e-03	2.71e-01	2.43e-02
GABA B receptor activation	31	8.98e-03	2.71e-01	2.43e-02
MET promotes cell motility	26	9.05e-03	2.96e-01	2.44e-02
Beta-catenin phosphorylation cascade	17	9.11e-03	3.65e-01	2.46e-02
Integrin cell surface interactions	52	9.18e-03	2.09e-01	2.47e-02
Effects of PIP2 hydrolysis	24	9.24e-03	-3.07e-01	2.48e-02
FCGR3A-mediated phagocytosis	121	9.35e-03	1.37e-01	2.50e-02
Leishmania phagocytosis	121	9.35e-03	1.37e-01	2.50e-02
Parasite infection	121	9.35e-03	1.37e-01	2.50e-02
Intra-Golgi traffic	43	9.48e-03	2.29e-01	2.52e-02
Collagen formation	66	9.52e-03	1.85e-01	2.53e-02
Transport of Mature mRNAs Derived from Intronless Transcripts	43	9.62e-03	-2.28e-01	2.55e-02
Removal of the Flap Intermediate	14	9.82e-03	-3.99e-01	2.60e-02
Josephin domain DUBs	10	9.89e-03	4.71e-01	2.61e-02
Assembly of the pre-replicative complex	67	9.99e-03	1.82e-01	2.63e-02
Endogenous sterols	17	1.00e-02	3.61e-01	2.64e-02
Glycogen breakdown (glycogenolysis)	13	1.01e-02	4.12e-01	2.65e-02
G beta:gamma signalling through CDC42	17	1.02e-02	3.60e-01	2.67e-02
Regulation of IFNG signaling	14	1.04e-02	3.96e-01	2.71e-02
Prefoldin mediated transfer of substrate to CCT/TriC	26	1.04e-02	2.90e-01	2.71e-02
Cleavage of the damaged pyrimidine	29	1.04e-02	2.75e-01	2.71e-02
Depyrimidination	29	1.04e-02	2.75e-01	2.71e-02
Recognition and association of DNA glycosylase with site containing an affected pyrimidine	29	1.04e-02	2.75e-01	2.71e-02
L13a-mediated translational silencing of Ceruloplasmin expression	110	1.05e-02	-1.41e-01	2.73e-02
TNFR2 non-canonical NF-kB pathway	96	1.06e-02	1.51e-01	2.74e-02
HCMV Infection	96	1.07e-02	1.51e-01	2.75e-02
Protein localization	157	1.07e-02	1.18e-01	2.75e-02
Gap junction trafficking and regulation	16	1.08e-02	3.68e-01	2.76e-02
Transport of the SLBP Dependant Mature mRNA	36	1.08e-02	-2.46e-01	2.76e-02
Cristae formation	31	1.08e-02	2.65e-01	2.77e-02
Cyclin A:Cdk2-associated events at S phase entry	85	1.09e-02	1.60e-01	2.79e-02
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	11	1.09e-02	4.43e-01	2.79e-02
Signaling by NOTCH3	43	1.11e-02	2.24e-01	2.83e-02
MAP3K8 (TPL2)-dependent MAPK1/3 activation	16	1.11e-02	3.67e-01	2.83e-02
Negative regulation of FGFR1 signaling	24	1.12e-02	2.99e-01	2.83e-02
Formation of Fibrin Clot (Clotting Cascade)	26	1.12e-02	2.87e-01	2.84e-02
TRAF6-mediated induction of TAK1 complex within TLR4 complex	16	1.15e-02	3.65e-01	2.90e-02
Metabolism of porphyrins	22	1.15e-02	3.11e-01	2.90e-02
Biotin transport and metabolism	11	1.16e-02	-4.40e-01	2.91e-02
Glycogen synthesis	13	1.16e-02	4.04e-01	2.92e-02
Sphingolipid de novo biosynthesis	42	1.19e-02	2.24e-01	2.97e-02
Pyruvate metabolism and Citric Acid (TCA) cycle	52	1.19e-02	2.02e-01	2.97e-02
Alpha-protein kinase 1 signaling pathway	11	1.19e-02	4.38e-01	2.98e-02
Nucleotide salvage	21	1.20e-02	3.17e-01	3.00e-02
ATF6 (ATF6-alpha) activates chaperones	12	1.23e-02	4.17e-01	3.07e-02
RHO GTPases activate IQGAPs	11	1.26e-02	4.34e-01	3.13e-02
Formation of the beta-catenin:TCF transactivating complex	46	1.26e-02	2.13e-01	3.13e-02
Negative regulation of FGFR4 signaling	21	1.27e-02	3.14e-01	3.15e-02
Signaling by FGFR4	31	1.28e-02	2.58e-01	3.16e-02
Metabolism of steroid hormones	21	1.32e-02	3.12e-01	3.27e-02
Circadian Clock	67	1.37e-02	1.74e-01	3.37e-02
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	22	1.37e-02	3.03e-01	3.38e-02
Mitochondrial tRNA aminoacylation	21	1.39e-02	-3.10e-01	3.41e-02
VxPx cargo-targeting to cilium	19	1.40e-02	3.25e-01	3.44e-02
Signal regulatory protein family interactions	12	1.44e-02	4.08e-01	3.52e-02
ATF6 (ATF6-alpha) activates chaperone genes	10	1.44e-02	4.47e-01	3.52e-02
G beta:gamma signalling through PLC beta	17	1.48e-02	3.41e-01	3.61e-02
SUMOylation of DNA damage response and repair proteins	77	1.48e-02	-1.61e-01	3.62e-02
Base-Excision Repair, AP Site Formation	31	1.50e-02	2.52e-01	3.63e-02
Cap-dependent Translation Initiation	118	1.50e-02	-1.30e-01	3.63e-02
Eukaryotic Translation Initiation	118	1.50e-02	-1.30e-01	3.63e-02
EPH-ephrin mediated repulsion of cells	40	1.52e-02	2.22e-01	3.67e-02
HCMV Late Events	69	1.53e-02	1.69e-01	3.70e-02
Interleukin-12 signaling	44	1.54e-02	2.11e-01	3.72e-02
Activated NOTCH1 Transmits Signal to the Nucleus	27	1.58e-02	2.68e-01	3.79e-02
SRP-dependent cotranslational protein targeting to membrane	111	1.62e-02	-1.32e-01	3.89e-02
O-glycosylation of TSR domain-containing proteins	26	1.63e-02	-2.72e-01	3.91e-02
CD28 dependent PI3K/Akt signaling	22	1.64e-02	-2.96e-01	3.91e-02
NGF-stimulated transcription	31	1.64e-02	2.49e-01	3.91e-02
Regulated proteolysis of p75NTR	11	1.65e-02	4.18e-01	3.92e-02
G alpha (12/13) signalling events	69	1.67e-02	1.67e-01	3.98e-02
Response of EIF2AK1 (HRI) to heme deficiency	14	1.68e-02	3.69e-01	4.00e-02
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	32	1.70e-02	2.44e-01	4.04e-02
DNA Repair	289	1.71e-02	-8.15e-02	4.04e-02
Peroxisomal protein import	57	1.71e-02	1.83e-01	4.04e-02
Cell-Cell communication	89	1.71e-02	1.46e-01	4.04e-02
Cell-extracellular matrix interactions	14	1.73e-02	3.68e-01	4.06e-02
SIRT1 negatively regulates rRNA expression	24	1.78e-02	2.79e-01	4.19e-02
RNA Polymerase III Transcription Initiation From Type 1 Promoter	28	1.78e-02	-2.59e-01	4.19e-02
Presynaptic function of Kainate receptors	18	1.80e-02	3.22e-01	4.22e-02
Leading Strand Synthesis	14	1.83e-02	-3.64e-01	4.27e-02
Polymerase switching	14	1.83e-02	-3.64e-01	4.27e-02
Postmitotic nuclear pore complex (NPC) reformation	27	1.83e-02	-2.62e-01	4.27e-02
SUMOylation of immune response proteins	11	1.84e-02	4.11e-01	4.27e-02
SLC-mediated transmembrane transport	180	1.84e-02	1.02e-01	4.27e-02
Cell junction organization	60	1.85e-02	1.76e-01	4.28e-02
Formation of tubulin folding intermediates by CCT/TriC	22	1.87e-02	2.90e-01	4.33e-02
HDR through MMEJ (alt-NHEJ)	10	1.89e-02	-4.29e-01	4.37e-02
G beta:gamma signalling through PI3Kgamma	22	1.93e-02	2.88e-01	4.46e-02
Potential therapeutics for SARS	78	1.94e-02	1.53e-01	4.47e-02
Translation of Replicase and Assembly of the Replication Transcription Complex	12	1.98e-02	3.88e-01	4.56e-02
Keratinization	33	2.01e-02	2.34e-01	4.62e-02
Activation of G protein gated Potassium channels	20	2.03e-02	3.00e-01	4.63e-02
G protein gated Potassium channels	20	2.03e-02	3.00e-01	4.63e-02
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	20	2.03e-02	3.00e-01	4.63e-02
Diseases associated with O-glycosylation of proteins	48	2.04e-02	-1.93e-01	4.66e-02
Butyrophilin (BTN) family interactions	10	2.05e-02	-4.23e-01	4.67e-02
Apoptotic factor-mediated response	18	2.10e-02	3.14e-01	4.77e-02
Ca-dependent events	29	2.11e-02	2.47e-01	4.79e-02
FOXO-mediated transcription of cell death genes	16	2.16e-02	3.32e-01	4.89e-02
RORA activates gene expression	18	2.17e-02	3.12e-01	4.91e-02
Regulation of PTEN gene transcription	59	2.23e-02	1.72e-01	5.03e-02
Cilium Assembly	180	2.26e-02	-9.85e-02	5.10e-02
RNA Polymerase I Transcription Initiation	44	2.27e-02	-1.98e-01	5.12e-02
Transport of Mature mRNA derived from an Intron-Containing Transcript	72	2.30e-02	-1.55e-01	5.17e-02
Interferon gamma signaling	83	2.32e-02	-1.44e-01	5.21e-02
Nucleobase catabolism	28	2.33e-02	2.48e-01	5.21e-02
TRAF6 mediated NF-kB activation	23	2.38e-02	2.72e-01	5.32e-02
Negative regulation of the PI3K/AKT network	87	2.39e-02	1.40e-01	5.34e-02
Oncogene Induced Senescence	33	2.40e-02	2.27e-01	5.35e-02
Metabolism of Angiotensinogen to Angiotensins	11	2.43e-02	3.92e-01	5.40e-02
HuR (ELAVL1) binds and stabilizes mRNA	10	2.45e-02	4.11e-01	5.44e-02
Telomere C-strand synthesis initiation	13	2.45e-02	-3.60e-01	5.44e-02
PKA activation in glucagon signalling	14	2.47e-02	3.47e-01	5.46e-02
Pyruvate metabolism	28	2.48e-02	2.45e-01	5.49e-02
RHO GTPases activate KTN1	11	2.49e-02	3.91e-01	5.50e-02
RNA Polymerase III Transcription Initiation From Type 2 Promoter	27	2.59e-02	-2.48e-01	5.70e-02
ISG15 antiviral mechanism	72	2.60e-02	-1.52e-01	5.73e-02
Gluconeogenesis	28	2.62e-02	2.43e-01	5.75e-02
Nucleobase biosynthesis	13	2.64e-02	-3.56e-01	5.80e-02
NOD1/2 Signaling Pathway	32	2.68e-02	2.26e-01	5.86e-02
Heme degradation	10	2.73e-02	4.03e-01	5.97e-02
Formation of apoptosome	11	2.75e-02	3.84e-01	5.98e-02
Regulation of the apoptosome activity	11	2.75e-02	3.84e-01	5.98e-02
Triglyceride catabolism	16	2.79e-02	3.17e-01	6.07e-02
Interleukin-6 signaling	10	2.81e-02	4.01e-01	6.11e-02
NOTCH3 Activation and Transmission of Signal to the Nucleus	23	2.83e-02	2.64e-01	6.13e-02
DNA Damage/Telomere Stress Induced Senescence	44	2.85e-02	1.91e-01	6.17e-02
Citric acid cycle (TCA cycle)	22	2.86e-02	2.70e-01	6.19e-02
NoRC negatively regulates rRNA expression	59	2.92e-02	1.64e-01	6.31e-02
Arachidonic acid metabolism	43	2.93e-02	1.92e-01	6.31e-02
Regulation of TP53 Activity	152	2.96e-02	-1.02e-01	6.37e-02
Common Pathway of Fibrin Clot Formation	14	2.97e-02	3.36e-01	6.39e-02
Frs2-mediated activation	11	3.00e-02	3.78e-01	6.43e-02
G beta:gamma signalling through BTK	15	3.01e-02	3.23e-01	6.44e-02
Negative regulation of MAPK pathway	42	3.02e-02	1.93e-01	6.46e-02
SUMOylation of SUMOylation proteins	35	3.02e-02	-2.12e-01	6.46e-02
Defective B3GALTL causes Peters-plus syndrome (PpS)	25	3.08e-02	-2.50e-01	6.55e-02
RIPK1-mediated regulated necrosis	29	3.09e-02	2.32e-01	6.55e-02
Regulated Necrosis	29	3.09e-02	2.32e-01	6.55e-02
Regulation of necroptotic cell death	29	3.09e-02	2.32e-01	6.55e-02
Myogenesis	21	3.11e-02	2.72e-01	6.59e-02
Peptide hormone metabolism	50	3.13e-02	1.76e-01	6.61e-02
Retrograde transport at the Trans-Golgi-Network	49	3.17e-02	1.77e-01	6.69e-02
SUMOylation of RNA binding proteins	47	3.20e-02	-1.81e-01	6.74e-02
Activation of the AP-1 family of transcription factors	10	3.25e-02	3.90e-01	6.85e-02
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	26	3.26e-02	-2.42e-01	6.85e-02
Signalling to RAS	19	3.27e-02	2.83e-01	6.86e-02
Diseases associated with glycosylation precursor biosynthesis	18	3.27e-02	2.91e-01	6.86e-02
Cytochrome c-mediated apoptotic response	13	3.33e-02	3.41e-01	6.96e-02
Metalloprotease DUBs	21	3.33e-02	2.68e-01	6.96e-02
Cell death signalling via NRAGE, NRIF and NADE	70	3.34e-02	1.47e-01	6.97e-02
Signaling by FGFR1	38	3.40e-02	1.99e-01	7.08e-02
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	16	3.42e-02	3.06e-01	7.11e-02
Post-chaperonin tubulin folding pathway	19	3.43e-02	2.80e-01	7.12e-02
FCGR activation	76	3.45e-02	-1.40e-01	7.14e-02
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon	17	3.50e-02	2.95e-01	7.25e-02
Transcriptional Regulation by E2F6	34	3.52e-02	-2.09e-01	7.27e-02
FCERI mediated NF-kB activation	138	3.53e-02	1.04e-01	7.29e-02
Transport of Mature Transcript to Cytoplasm	81	3.56e-02	-1.35e-01	7.34e-02
The role of Nef in HIV-1 replication and disease pathogenesis	28	3.58e-02	2.29e-01	7.37e-02
DAP12 interactions	39	3.59e-02	1.94e-01	7.38e-02
NR1H2 and NR1H3-mediated signaling	39	3.61e-02	1.94e-01	7.41e-02
Mitotic G2-G2/M phases	182	3.62e-02	9.00e-02	7.41e-02
Separation of Sister Chromatids	168	3.62e-02	9.36e-02	7.41e-02
Activation of BAD and translocation to mitochondria	15	3.69e-02	3.11e-01	7.53e-02
Apoptosis induced DNA fragmentation	10	3.79e-02	3.79e-01	7.73e-02
Nuclear signaling by ERBB4	24	3.90e-02	2.43e-01	7.94e-02
FGFR1 mutant receptor activation	23	3.91e-02	2.48e-01	7.96e-02
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	18	3.97e-02	2.80e-01	8.05e-02
Signaling by Ligand-Responsive EGFR Variants in Cancer	18	3.97e-02	2.80e-01	8.05e-02
Signaling by cytosolic FGFR1 fusion mutants	17	4.00e-02	2.88e-01	8.10e-02
Pexophagy	11	4.02e-02	3.57e-01	8.13e-02
Intrinsic Pathway for Apoptosis	53	4.03e-02	1.63e-01	8.14e-02
Translesion synthesis by REV1	16	4.13e-02	-2.95e-01	8.32e-02
DNA Double-Strand Break Repair	135	4.22e-02	-1.01e-01	8.50e-02
Defects in vitamin and cofactor metabolism	21	4.23e-02	-2.56e-01	8.50e-02
Mitotic Prophase	98	4.33e-02	1.18e-01	8.69e-02
Termination of translesion DNA synthesis	32	4.40e-02	-2.06e-01	8.81e-02
RNA Polymerase II Pre-transcription Events	78	4.41e-02	1.32e-01	8.81e-02
Meiotic synapsis	45	4.48e-02	1.73e-01	8.95e-02
SHC1 events in ERBB2 signaling	17	4.54e-02	2.80e-01	9.04e-02
Diseases of DNA repair	10	4.55e-02	-3.65e-01	9.04e-02
B-WICH complex positively regulates rRNA expression	44	4.55e-02	1.74e-01	9.04e-02
HDMs demethylate histones	22	4.64e-02	2.45e-01	9.20e-02
Biosynthesis of specialized proresolving mediators (SPMs)	16	4.64e-02	2.88e-01	9.20e-02
Aggrephagy	22	4.66e-02	2.45e-01	9.23e-02
Biological oxidations	137	4.75e-02	9.81e-02	9.39e-02
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	14	4.78e-02	-3.06e-01	9.42e-02
Surfactant metabolism	22	4.79e-02	2.44e-01	9.42e-02
Formation of RNA Pol II elongation complex	57	4.80e-02	1.51e-01	9.42e-02
RNA Polymerase II Transcription Elongation	57	4.80e-02	1.51e-01	9.42e-02
Elastic fibre formation	32	4.85e-02	2.01e-01	9.53e-02
p75NTR signals via NF-kB	15	4.88e-02	2.94e-01	9.57e-02
GP1b-IX-V activation signalling	10	5.04e-02	3.57e-01	9.86e-02
MET activates RAS signaling	10	5.12e-02	3.56e-01	1.00e-01
RET signaling	32	5.21e-02	1.98e-01	1.02e-01
Initiation of Nuclear Envelope (NE) Reformation	19	5.27e-02	2.57e-01	1.03e-01
Misspliced GSK3beta mutants stabilize beta-catenin	15	5.33e-02	2.88e-01	1.03e-01
S33 mutants of beta-catenin aren’t phosphorylated	15	5.33e-02	2.88e-01	1.03e-01
S37 mutants of beta-catenin aren’t phosphorylated	15	5.33e-02	2.88e-01	1.03e-01
S45 mutants of beta-catenin aren’t phosphorylated	15	5.33e-02	2.88e-01	1.03e-01
T41 mutants of beta-catenin aren’t phosphorylated	15	5.33e-02	2.88e-01	1.03e-01
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex	15	5.33e-02	2.88e-01	1.03e-01
Sialic acid metabolism	28	5.34e-02	2.11e-01	1.03e-01
Nuclear Pore Complex (NPC) Disassembly	36	5.36e-02	-1.86e-01	1.03e-01
Signaling by ERBB2	44	5.38e-02	1.68e-01	1.04e-01
Gap-filling DNA repair synthesis and ligation in GG-NER	25	5.39e-02	-2.23e-01	1.04e-01
Laminin interactions	21	5.43e-02	2.43e-01	1.04e-01
SUMOylation of ubiquitinylation proteins	39	5.48e-02	-1.78e-01	1.05e-01
G2/M Transition	180	5.50e-02	8.29e-02	1.05e-01
Regulation of signaling by CBL	18	5.52e-02	2.61e-01	1.05e-01
Processive synthesis on the C-strand of the telomere	19	5.52e-02	-2.54e-01	1.05e-01
Metabolism of fat-soluble vitamins	28	5.67e-02	2.08e-01	1.08e-01
Orc1 removal from chromatin	70	5.76e-02	1.31e-01	1.10e-01
Synthesis of Leukotrienes (LT) and Eoxins (EX)	15	5.77e-02	2.83e-01	1.10e-01
TNFR1-induced proapoptotic signaling	12	5.78e-02	-3.16e-01	1.10e-01
Trafficking and processing of endosomal TLR	13	5.88e-02	3.03e-01	1.11e-01
Pyrimidine salvage	10	5.91e-02	3.45e-01	1.12e-01
Chromosome Maintenance	105	5.92e-02	-1.07e-01	1.12e-01
Rap1 signalling	13	5.95e-02	3.02e-01	1.12e-01
Classical antibody-mediated complement activation	69	5.97e-02	-1.31e-01	1.13e-01
RNA Polymerase I Promoter Escape	44	6.00e-02	1.64e-01	1.13e-01
Glycogen storage diseases	13	6.01e-02	3.01e-01	1.13e-01
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	13	6.05e-02	3.01e-01	1.13e-01
Signaling by the B Cell Receptor (BCR)	163	6.05e-02	8.52e-02	1.13e-01
TICAM1, RIP1-mediated IKK complex recruitment	19	6.09e-02	2.48e-01	1.14e-01
Constitutive Signaling by EGFRvIII	14	6.17e-02	2.88e-01	1.15e-01
Signaling by EGFRvIII in Cancer	14	6.17e-02	2.88e-01	1.15e-01
Intrinsic Pathway of Fibrin Clot Formation	16	6.18e-02	2.70e-01	1.15e-01
p38MAPK events	13	6.19e-02	2.99e-01	1.15e-01
Translesion synthesis by POLI	17	6.22e-02	-2.61e-01	1.16e-01
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	33	6.33e-02	1.87e-01	1.18e-01
Downregulation of ERBB2 signaling	24	6.39e-02	2.18e-01	1.18e-01
G alpha (q) signalling events	134	6.48e-02	9.24e-02	1.20e-01
Phase 0 - rapid depolarisation	22	6.53e-02	-2.27e-01	1.21e-01
SUMOylation of chromatin organization proteins	57	6.56e-02	-1.41e-01	1.21e-01
Signaling by FGFR1 in disease	30	6.60e-02	1.94e-01	1.22e-01
FOXO-mediated transcription	59	6.72e-02	1.38e-01	1.24e-01
Regulation of TP53 Activity through Acetylation	29	6.76e-02	-1.96e-01	1.24e-01
SHC1 events in ERBB4 signaling	10	6.80e-02	3.33e-01	1.25e-01
Prostacyclin signalling through prostacyclin receptor	16	6.82e-02	2.63e-01	1.25e-01
Dual Incision in GG-NER	41	6.86e-02	-1.64e-01	1.26e-01
Tie2 Signaling	16	7.05e-02	2.61e-01	1.29e-01
Caspase activation via Death Receptors in the presence of ligand	16	7.20e-02	2.60e-01	1.32e-01
CaM pathway	27	7.26e-02	2.00e-01	1.32e-01
Calmodulin induced events	27	7.26e-02	2.00e-01	1.32e-01
EPHA-mediated growth cone collapse	13	7.31e-02	2.87e-01	1.33e-01
PKA activation	15	7.31e-02	2.67e-01	1.33e-01
PRC2 methylates histones and DNA	29	7.36e-02	1.92e-01	1.33e-01
Retinoid metabolism and transport	24	7.37e-02	2.11e-01	1.34e-01
Chondroitin sulfate biosynthesis	12	7.62e-02	2.96e-01	1.38e-01
Negative regulation of FGFR2 signaling	23	7.66e-02	2.13e-01	1.38e-01
RNA Polymerase III Transcription Initiation	36	7.66e-02	-1.71e-01	1.38e-01
Insulin receptor signalling cascade	39	7.68e-02	1.64e-01	1.38e-01
SUMOylation of intracellular receptors	26	7.68e-02	2.00e-01	1.38e-01
Acyl chain remodelling of PC	19	7.71e-02	2.34e-01	1.38e-01
BMAL1:CLOCK,NPAS2 activates circadian gene expression	25	7.71e-02	2.04e-01	1.38e-01
Striated Muscle Contraction	24	7.76e-02	2.08e-01	1.39e-01
Inwardly rectifying K+ channels	24	7.79e-02	2.08e-01	1.40e-01
Resolution of D-Loop Structures	33	7.85e-02	-1.77e-01	1.40e-01
Apoptotic cleavage of cellular proteins	34	7.85e-02	1.74e-01	1.40e-01
Metabolism of nucleotides	86	7.90e-02	1.10e-01	1.41e-01
Transcriptional Regulation by MECP2	47	8.13e-02	1.47e-01	1.45e-01
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	18	8.14e-02	2.37e-01	1.45e-01
Signaling by Hippo	18	8.17e-02	2.37e-01	1.45e-01
ERBB2 Regulates Cell Motility	10	8.23e-02	3.17e-01	1.46e-01
Listeria monocytogenes entry into host cells	17	8.25e-02	2.43e-01	1.46e-01
CD22 mediated BCR regulation	59	8.26e-02	-1.31e-01	1.46e-01
Signaling by ERBB2 in Cancer	21	8.27e-02	2.19e-01	1.46e-01
Attenuation phase	23	8.28e-02	2.09e-01	1.46e-01
Creation of C4 and C2 activators	71	8.33e-02	-1.19e-01	1.47e-01
Signaling by PDGFRA extracellular domain mutants	12	8.43e-02	2.88e-01	1.48e-01
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants	12	8.43e-02	2.88e-01	1.48e-01
Mitotic Telophase/Cytokinesis	13	8.47e-02	2.76e-01	1.49e-01
PI Metabolism	80	8.53e-02	1.11e-01	1.50e-01
Translesion synthesis by POLK	17	8.56e-02	-2.41e-01	1.50e-01
Glucose metabolism	84	8.62e-02	1.08e-01	1.51e-01
Role of phospholipids in phagocytosis	88	8.64e-02	-1.06e-01	1.51e-01
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	16	8.67e-02	2.47e-01	1.51e-01
Initial triggering of complement	78	8.68e-02	-1.12e-01	1.51e-01
Downregulation of TGF-beta receptor signaling	26	8.73e-02	1.94e-01	1.52e-01
Synthesis of substrates in N-glycan biosythesis	58	8.82e-02	1.29e-01	1.53e-01
Resolution of D-loop Structures through Holliday Junction Intermediates	32	8.89e-02	-1.74e-01	1.54e-01
Synthesis of PIPs at the plasma membrane	52	8.98e-02	1.36e-01	1.56e-01
Mitophagy	28	8.99e-02	1.85e-01	1.56e-01
Negative epigenetic regulation of rRNA expression	62	9.09e-02	1.24e-01	1.57e-01
SUMOylation of DNA replication proteins	46	9.14e-02	-1.44e-01	1.58e-01
Collagen biosynthesis and modifying enzymes	48	9.20e-02	1.41e-01	1.59e-01
Nuclear Envelope (NE) Reassembly	69	9.41e-02	1.17e-01	1.62e-01
AMER1 mutants destabilize the destruction complex	14	9.52e-02	2.58e-01	1.63e-01
APC truncation mutants have impaired AXIN binding	14	9.52e-02	2.58e-01	1.63e-01
AXIN missense mutants destabilize the destruction complex	14	9.52e-02	2.58e-01	1.63e-01
AXIN mutants destabilize the destruction complex, activating WNT signaling	14	9.52e-02	2.58e-01	1.63e-01
Truncations of AMER1 destabilize the destruction complex	14	9.52e-02	2.58e-01	1.63e-01
truncated APC mutants destabilize the destruction complex	14	9.52e-02	2.58e-01	1.63e-01
Signaling by FGFR in disease	50	9.53e-02	1.36e-01	1.63e-01
Receptor Mediated Mitophagy	11	9.58e-02	2.90e-01	1.63e-01
Chaperone Mediated Autophagy	20	9.61e-02	2.15e-01	1.64e-01
Acyl chain remodelling of PI	10	9.74e-02	3.03e-01	1.65e-01
NOTCH3 Intracellular Domain Regulates Transcription	21	9.74e-02	2.09e-01	1.65e-01
Metabolism of nitric oxide: NOS3 activation and regulation	12	9.79e-02	2.76e-01	1.66e-01
Potassium Channels	64	9.86e-02	1.19e-01	1.67e-01
Plasma lipoprotein remodeling	18	9.94e-02	2.24e-01	1.68e-01
HIV Transcription Initiation	45	9.99e-02	1.42e-01	1.68e-01
RNA Polymerase II HIV Promoter Escape	45	9.99e-02	1.42e-01	1.68e-01
RNA Polymerase II Promoter Escape	45	9.99e-02	1.42e-01	1.68e-01
RNA Polymerase II Transcription Initiation	45	9.99e-02	1.42e-01	1.68e-01
RNA Polymerase II Transcription Initiation And Promoter Clearance	45	9.99e-02	1.42e-01	1.68e-01
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	45	9.99e-02	1.42e-01	1.68e-01
RNA polymerase II transcribes snRNA genes	72	1.01e-01	1.12e-01	1.69e-01
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	14	1.01e-01	-2.53e-01	1.69e-01
Chemokine receptors bind chemokines	39	1.03e-01	-1.51e-01	1.73e-01
Triglyceride metabolism	25	1.05e-01	1.87e-01	1.75e-01
Mismatch Repair	15	1.06e-01	-2.41e-01	1.77e-01
Switching of origins to a post-replicative state	90	1.07e-01	9.84e-02	1.78e-01
Homology Directed Repair	110	1.07e-01	-8.89e-02	1.79e-01
mRNA decay by 3’ to 5’ exoribonuclease	16	1.07e-01	-2.32e-01	1.79e-01
TICAM1,TRAF6-dependent induction of TAK1 complex	11	1.08e-01	2.80e-01	1.79e-01
Activation of kainate receptors upon glutamate binding	26	1.08e-01	1.82e-01	1.79e-01
PI3K/AKT Signaling in Cancer	81	1.08e-01	1.03e-01	1.79e-01
Insulin processing	21	1.09e-01	2.02e-01	1.81e-01
Pausing and recovery of Tat-mediated HIV elongation	30	1.10e-01	1.69e-01	1.81e-01
Tat-mediated HIV elongation arrest and recovery	30	1.10e-01	1.69e-01	1.81e-01
Translation	295	1.10e-01	-5.41e-02	1.81e-01
MASTL Facilitates Mitotic Progression	10	1.10e-01	2.92e-01	1.82e-01
NF-kB is activated and signals survival	12	1.11e-01	2.66e-01	1.82e-01
Mitochondrial iron-sulfur cluster biogenesis	13	1.11e-01	2.55e-01	1.83e-01
Signaling by PDGF	44	1.12e-01	1.39e-01	1.83e-01
Host Interactions of HIV factors	130	1.12e-01	8.07e-02	1.83e-01
Interleukin-27 signaling	11	1.12e-01	2.77e-01	1.83e-01
BBSome-mediated cargo-targeting to cilium	22	1.14e-01	-1.94e-01	1.87e-01
Heme biosynthesis	14	1.15e-01	2.43e-01	1.89e-01
Scavenging by Class A Receptors	12	1.18e-01	2.61e-01	1.92e-01
HIV elongation arrest and recovery	32	1.18e-01	1.60e-01	1.92e-01
Pausing and recovery of HIV elongation	32	1.18e-01	1.60e-01	1.92e-01
Glutathione conjugation	26	1.18e-01	1.77e-01	1.92e-01
Peroxisomal lipid metabolism	27	1.19e-01	1.74e-01	1.92e-01
Recognition of DNA damage by PCNA-containing replication complex	30	1.19e-01	-1.65e-01	1.92e-01
Depolymerisation of the Nuclear Lamina	15	1.19e-01	2.32e-01	1.93e-01
Class C/3 (Metabotropic glutamate/pheromone receptors)	11	1.19e-01	-2.71e-01	1.93e-01
Assembly of collagen fibrils and other multimeric structures	42	1.20e-01	1.39e-01	1.93e-01
TP53 Regulates Transcription of Cell Death Genes	43	1.20e-01	1.37e-01	1.94e-01
O-linked glycosylation of mucins	47	1.21e-01	1.31e-01	1.95e-01
Fatty acyl-CoA biosynthesis	35	1.21e-01	1.51e-01	1.95e-01
Interleukin-15 signaling	14	1.22e-01	2.38e-01	1.97e-01
Carnitine metabolism	10	1.23e-01	2.82e-01	1.98e-01
Phase I - Functionalization of compounds	65	1.24e-01	1.10e-01	1.99e-01
Removal of the Flap Intermediate from the C-strand	17	1.25e-01	-2.15e-01	2.01e-01
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	21	1.26e-01	1.93e-01	2.02e-01
Beta-oxidation of very long chain fatty acids	10	1.28e-01	2.78e-01	2.04e-01
Interleukin-6 family signaling	18	1.30e-01	2.06e-01	2.08e-01
Glycolysis	67	1.32e-01	1.06e-01	2.10e-01
Phase II - Conjugation of compounds	67	1.34e-01	1.06e-01	2.13e-01
rRNA processing in the mitochondrion	29	1.34e-01	-1.61e-01	2.14e-01
Regulation of TP53 Activity through Phosphorylation	88	1.35e-01	-9.21e-02	2.15e-01
PINK1-PRKN Mediated Mitophagy	21	1.35e-01	1.88e-01	2.15e-01
p75NTR recruits signalling complexes	12	1.36e-01	2.49e-01	2.15e-01
Carboxyterminal post-translational modifications of tubulin	27	1.37e-01	1.65e-01	2.18e-01
NCAM1 interactions	23	1.39e-01	-1.78e-01	2.19e-01
ZBP1(DAI) mediated induction of type I IFNs	20	1.39e-01	1.91e-01	2.20e-01
Transport of vitamins, nucleosides, and related molecules	33	1.41e-01	1.48e-01	2.22e-01
Viral Messenger RNA Synthesis	44	1.42e-01	-1.28e-01	2.24e-01
Downstream signal transduction	27	1.42e-01	1.63e-01	2.24e-01
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	14	1.44e-01	2.26e-01	2.26e-01
NRIF signals cell death from the nucleus	15	1.45e-01	2.18e-01	2.27e-01
cGMP effects	12	1.45e-01	2.43e-01	2.28e-01
Acyl chain remodelling of PE	20	1.45e-01	1.88e-01	2.28e-01
Purine ribonucleoside monophosphate biosynthesis	10	1.47e-01	-2.65e-01	2.30e-01
Peptide ligand-binding receptors	97	1.47e-01	8.52e-02	2.30e-01
Bile acid and bile salt metabolism	28	1.49e-01	1.58e-01	2.32e-01
Metabolism of cofactors	19	1.49e-01	1.91e-01	2.32e-01
CD209 (DC-SIGN) signaling	20	1.50e-01	1.86e-01	2.33e-01
Ca2+ pathway	57	1.50e-01	1.10e-01	2.33e-01
Signaling by ERBB2 KD Mutants	20	1.50e-01	1.86e-01	2.33e-01
RA biosynthesis pathway	13	1.50e-01	-2.30e-01	2.33e-01
PI3K events in ERBB2 signaling	11	1.53e-01	2.49e-01	2.37e-01
Constitutive Signaling by AKT1 E17K in Cancer	26	1.55e-01	1.61e-01	2.40e-01
Amine ligand-binding receptors	10	1.55e-01	-2.60e-01	2.40e-01
Constitutive Signaling by Overexpressed ERBB2	11	1.55e-01	2.48e-01	2.40e-01
tRNA processing in the mitochondrion	32	1.55e-01	-1.45e-01	2.40e-01
Synthesis of very long-chain fatty acyl-CoAs	22	1.56e-01	1.75e-01	2.41e-01
GRB2 events in ERBB2 signaling	11	1.58e-01	2.46e-01	2.43e-01
RIP-mediated NFkB activation via ZBP1	17	1.60e-01	1.97e-01	2.46e-01
Formation of TC-NER Pre-Incision Complex	53	1.61e-01	1.11e-01	2.47e-01
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	73	1.62e-01	9.47e-02	2.49e-01
IRAK2 mediated activation of TAK1 complex	10	1.62e-01	2.55e-01	2.49e-01
TCR signaling	122	1.65e-01	7.28e-02	2.52e-01
Signaling by FGFR2	60	1.65e-01	1.04e-01	2.53e-01
RNA Polymerase III Chain Elongation	18	1.66e-01	-1.89e-01	2.53e-01
Metabolic disorders of biological oxidation enzymes	26	1.68e-01	1.56e-01	2.57e-01
Activation of NMDA receptors and postsynaptic events	58	1.69e-01	1.04e-01	2.58e-01
G alpha (s) signalling events	143	1.69e-01	6.66e-02	2.58e-01
Signaling by ERBB2 TMD/JMD mutants	17	1.72e-01	1.91e-01	2.62e-01
Tryptophan catabolism	12	1.75e-01	2.26e-01	2.66e-01
PKA-mediated phosphorylation of CREB	17	1.80e-01	1.88e-01	2.74e-01
Transcriptional Regulation by TP53	352	1.82e-01	4.14e-02	2.77e-01
Signaling by FGFR	69	1.85e-01	9.23e-02	2.81e-01
RUNX3 regulates NOTCH signaling	14	1.85e-01	2.05e-01	2.81e-01
ABC transporters in lipid homeostasis	14	1.86e-01	-2.04e-01	2.81e-01
HS-GAG biosynthesis	20	1.88e-01	1.70e-01	2.85e-01
Abortive elongation of HIV-1 transcript in the absence of Tat	23	1.92e-01	1.57e-01	2.90e-01
Meiotic recombination	38	1.94e-01	1.22e-01	2.92e-01
Plasma lipoprotein assembly	10	1.97e-01	2.36e-01	2.96e-01
Biosynthesis of DHA-derived SPMs	14	1.97e-01	1.99e-01	2.97e-01
Signaling by PDGFR in disease	19	2.02e-01	1.69e-01	3.03e-01
Translation of structural proteins	28	2.02e-01	1.39e-01	3.03e-01
Glutamate binding, activation of AMPA receptors and synaptic plasticity	20	2.05e-01	1.64e-01	3.07e-01
Trafficking of AMPA receptors	20	2.05e-01	1.64e-01	3.07e-01
Purine salvage	12	2.06e-01	2.11e-01	3.08e-01
RNA Pol II CTD phosphorylation and interaction with CE	27	2.08e-01	1.40e-01	3.10e-01
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	27	2.08e-01	1.40e-01	3.10e-01
Formation of the Early Elongation Complex	33	2.09e-01	1.26e-01	3.11e-01
Formation of the HIV-1 Early Elongation Complex	33	2.09e-01	1.26e-01	3.11e-01
Deadenylation of mRNA	22	2.09e-01	1.55e-01	3.11e-01
Adenylate cyclase inhibitory pathway	11	2.10e-01	2.19e-01	3.11e-01
Regulation of MECP2 expression and activity	28	2.10e-01	1.37e-01	3.12e-01
Cobalamin (Cbl, vitamin B12) transport and metabolism	17	2.11e-01	-1.75e-01	3.13e-01
Late Phase of HIV Life Cycle	131	2.13e-01	6.30e-02	3.16e-01
Nitric oxide stimulates guanylate cyclase	15	2.14e-01	1.85e-01	3.17e-01
Negative regulation of NMDA receptor-mediated neuronal transmission	14	2.14e-01	-1.92e-01	3.17e-01
Positive epigenetic regulation of rRNA expression	59	2.16e-01	9.31e-02	3.19e-01
Downstream TCR signaling	101	2.16e-01	7.12e-02	3.19e-01
Heparan sulfate/heparin (HS-GAG) metabolism	37	2.18e-01	1.17e-01	3.22e-01
Transcriptional activation of mitochondrial biogenesis	51	2.20e-01	9.92e-02	3.24e-01
Synthesis of bile acids and bile salts	24	2.21e-01	1.44e-01	3.24e-01
Dectin-2 family	19	2.22e-01	1.62e-01	3.26e-01
Adrenaline,noradrenaline inhibits insulin secretion	24	2.22e-01	1.44e-01	3.26e-01
Regulation of HSF1-mediated heat shock response	79	2.22e-01	-7.94e-02	3.26e-01
VEGFR2 mediated cell proliferation	18	2.23e-01	1.66e-01	3.26e-01
FCERI mediated Ca+2 mobilization	89	2.26e-01	-7.42e-02	3.31e-01
Cyclin A/B1/B2 associated events during G2/M transition	25	2.27e-01	1.40e-01	3.31e-01
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	18	2.27e-01	1.64e-01	3.32e-01
Transcription of the HIV genome	67	2.28e-01	8.51e-02	3.33e-01
Formation of HIV-1 elongation complex containing HIV-1 Tat	42	2.32e-01	1.07e-01	3.37e-01
HIV Transcription Elongation	42	2.32e-01	1.07e-01	3.37e-01
Tat-mediated elongation of the HIV-1 transcript	42	2.32e-01	1.07e-01	3.37e-01
ECM proteoglycans	35	2.32e-01	1.17e-01	3.37e-01
Synthesis of PIPs at the late endosome membrane	11	2.32e-01	2.08e-01	3.37e-01
FCGR3A-mediated IL10 synthesis	99	2.34e-01	-6.92e-02	3.39e-01
Chromatin modifying enzymes	218	2.34e-01	4.67e-02	3.39e-01
Chromatin organization	218	2.34e-01	4.67e-02	3.39e-01
Post NMDA receptor activation events	48	2.36e-01	9.88e-02	3.41e-01
Non-integrin membrane-ECM interactions	37	2.38e-01	1.12e-01	3.43e-01
Formation of HIV elongation complex in the absence of HIV Tat	44	2.38e-01	1.03e-01	3.43e-01
DAG and IP3 signaling	33	2.39e-01	1.18e-01	3.44e-01
Unblocking of NMDA receptors, glutamate binding and activation	12	2.42e-01	-1.95e-01	3.47e-01
Recruitment of NuMA to mitotic centrosomes	79	2.44e-01	-7.58e-02	3.50e-01
SUMOylation	166	2.45e-01	-5.23e-02	3.52e-01
Cytosolic iron-sulfur cluster assembly	13	2.46e-01	-1.86e-01	3.53e-01
Nuclear Envelope Breakdown	53	2.46e-01	-9.20e-02	3.53e-01
RAF-independent MAPK1/3 activation	21	2.47e-01	1.46e-01	3.53e-01
Signaling by NTRK2 (TRKB)	20	2.47e-01	1.50e-01	3.53e-01
Anchoring of the basal body to the plasma membrane	96	2.48e-01	-6.82e-02	3.54e-01
RNA Polymerase III Transcription Initiation From Type 3 Promoter	28	2.48e-01	-1.26e-01	3.54e-01
HSF1-dependent transactivation	29	2.49e-01	1.24e-01	3.54e-01
Other semaphorin interactions	16	2.52e-01	1.65e-01	3.59e-01
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	38	2.54e-01	-1.07e-01	3.61e-01
Miscellaneous transport and binding events	20	2.54e-01	1.47e-01	3.61e-01
Cellular response to heat stress	93	2.59e-01	-6.78e-02	3.67e-01
Assembly of active LPL and LIPC lipase complexes	10	2.60e-01	2.06e-01	3.68e-01
ADORA2B mediated anti-inflammatory cytokines production	73	2.62e-01	7.60e-02	3.71e-01
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	104	2.63e-01	-6.36e-02	3.71e-01
A tetrasaccharide linker sequence is required for GAG synthesis	17	2.65e-01	-1.56e-01	3.75e-01
Regulation of IFNA signaling	12	2.67e-01	1.85e-01	3.76e-01
Centrosome maturation	80	2.68e-01	-7.17e-02	3.76e-01
Recruitment of mitotic centrosome proteins and complexes	80	2.68e-01	-7.17e-02	3.76e-01
Signaling by NOTCH2	30	2.68e-01	1.17e-01	3.76e-01
G2/M Checkpoints	140	2.68e-01	5.42e-02	3.77e-01
Regulation of localization of FOXO transcription factors	12	2.71e-01	1.84e-01	3.80e-01
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	46	2.74e-01	9.31e-02	3.85e-01
Disorders of Developmental Biology	12	2.76e-01	1.82e-01	3.86e-01
Disorders of Nervous System Development	12	2.76e-01	1.82e-01	3.86e-01
Loss of function of MECP2 in Rett syndrome	12	2.76e-01	1.82e-01	3.86e-01
Pervasive developmental disorders	12	2.76e-01	1.82e-01	3.86e-01
Cytosolic tRNA aminoacylation	24	2.78e-01	-1.28e-01	3.88e-01
FRS-mediated FGFR3 signaling	11	2.78e-01	1.89e-01	3.88e-01
Synthesis of PE	12	2.79e-01	-1.81e-01	3.88e-01
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	25	2.80e-01	1.25e-01	3.89e-01
Amino acid transport across the plasma membrane	24	2.81e-01	1.27e-01	3.90e-01
Blood group systems biosynthesis	17	2.81e-01	1.51e-01	3.90e-01
DNA Damage Bypass	47	2.82e-01	-9.07e-02	3.91e-01
Mitotic Prometaphase	184	2.83e-01	-4.59e-02	3.92e-01
Cohesin Loading onto Chromatin	10	2.84e-01	1.96e-01	3.93e-01
Phase 2 - plateau phase	11	2.86e-01	-1.86e-01	3.95e-01
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	12	2.87e-01	1.77e-01	3.97e-01
Metal ion SLC transporters	21	2.88e-01	1.34e-01	3.98e-01
Olfactory Signaling Pathway	60	2.89e-01	7.91e-02	3.99e-01
RNA Polymerase I Transcription Termination	27	2.90e-01	-1.18e-01	4.00e-01
Keratan sulfate/keratin metabolism	27	2.91e-01	1.17e-01	4.01e-01
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	17	2.93e-01	-1.47e-01	4.03e-01
Signaling by FGFR2 IIIa TM	18	2.95e-01	1.43e-01	4.05e-01
Aflatoxin activation and detoxification	14	2.99e-01	1.60e-01	4.09e-01
Metabolism of amine-derived hormones	10	2.99e-01	-1.90e-01	4.09e-01
Telomere Extension By Telomerase	23	3.01e-01	-1.24e-01	4.12e-01
NRAGE signals death through JNK	53	3.03e-01	8.19e-02	4.13e-01
Signaling by ERBB2 ECD mutants	15	3.03e-01	1.54e-01	4.13e-01
Defects in cobalamin (B12) metabolism	13	3.03e-01	-1.65e-01	4.14e-01
Transcriptional regulation by small RNAs	63	3.04e-01	7.49e-02	4.14e-01
Vitamin B5 (pantothenate) metabolism	17	3.05e-01	1.44e-01	4.15e-01
VEGFR2 mediated vascular permeability	27	3.08e-01	1.13e-01	4.19e-01
CD28 dependent Vav1 pathway	12	3.08e-01	1.70e-01	4.19e-01
Acyl chain remodelling of PG	11	3.12e-01	1.76e-01	4.23e-01
RNA Polymerase III Abortive And Retractive Initiation	41	3.15e-01	-9.06e-02	4.27e-01
RNA Polymerase III Transcription	41	3.15e-01	-9.06e-02	4.27e-01
Formation of the ternary complex, and subsequently, the 43S complex	51	3.16e-01	-8.11e-02	4.28e-01
Interleukin-2 family signaling	38	3.19e-01	9.35e-02	4.31e-01
IGF1R signaling cascade	36	3.24e-01	9.49e-02	4.38e-01
HS-GAG degradation	16	3.25e-01	1.42e-01	4.38e-01
MET activates PTK2 signaling	15	3.25e-01	1.47e-01	4.38e-01
NCAM signaling for neurite out-growth	43	3.26e-01	-8.66e-02	4.39e-01
Transcriptional regulation of pluripotent stem cells	20	3.26e-01	1.27e-01	4.39e-01
Metabolism of folate and pterines	16	3.26e-01	1.42e-01	4.39e-01
Diseases of metabolism	190	3.27e-01	4.12e-02	4.39e-01
Cytochrome P450 - arranged by substrate type	36	3.28e-01	9.43e-02	4.40e-01
E2F mediated regulation of DNA replication	22	3.32e-01	-1.20e-01	4.45e-01
RAS processing	19	3.32e-01	1.28e-01	4.45e-01
SUMO E3 ligases SUMOylate target proteins	160	3.33e-01	-4.44e-02	4.45e-01
Polo-like kinase mediated events	16	3.33e-01	1.40e-01	4.45e-01
Early Phase of HIV Life Cycle	14	3.34e-01	-1.49e-01	4.46e-01
NOTCH2 Activation and Transmission of Signal to the Nucleus	20	3.35e-01	1.25e-01	4.47e-01
Nonhomologous End-Joining (NHEJ)	42	3.36e-01	8.58e-02	4.47e-01
Repression of WNT target genes	14	3.36e-01	-1.48e-01	4.47e-01
Inositol phosphate metabolism	42	3.38e-01	8.54e-02	4.50e-01
Platelet calcium homeostasis	22	3.38e-01	1.18e-01	4.50e-01
HIV Life Cycle	144	3.39e-01	4.61e-02	4.50e-01
DNA Double Strand Break Response	47	3.40e-01	8.05e-02	4.50e-01
FRS-mediated FGFR4 signaling	12	3.40e-01	1.59e-01	4.51e-01
Nef mediated downregulation of MHC class I complex cell surface expression	10	3.41e-01	1.74e-01	4.51e-01
Scavenging of heme from plasma	71	3.41e-01	-6.53e-02	4.51e-01
RNA Polymerase I Promoter Clearance	63	3.43e-01	6.91e-02	4.52e-01
RNA Polymerase I Transcription	63	3.43e-01	6.91e-02	4.52e-01
mitochondrial fatty acid beta-oxidation of saturated fatty acids	11	3.45e-01	1.64e-01	4.55e-01
Downstream signaling of activated FGFR3	16	3.48e-01	1.35e-01	4.59e-01
Class I peroxisomal membrane protein import	20	3.49e-01	-1.21e-01	4.59e-01
Activation of RAC1	11	3.49e-01	1.63e-01	4.59e-01
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	84	3.51e-01	-5.89e-02	4.61e-01
FRS-mediated FGFR1 signaling	14	3.52e-01	1.44e-01	4.61e-01
Regulation of beta-cell development	19	3.52e-01	1.23e-01	4.61e-01
Downregulation of ERBB2:ERBB3 signaling	12	3.53e-01	1.55e-01	4.62e-01
The phototransduction cascade	26	3.54e-01	-1.05e-01	4.63e-01
Regulation of expression of SLITs and ROBOs	161	3.55e-01	-4.22e-02	4.64e-01
Maturation of nucleoprotein	10	3.55e-01	-1.69e-01	4.64e-01
Translesion Synthesis by POLH	18	3.56e-01	-1.26e-01	4.64e-01
Degradation of cysteine and homocysteine	12	3.57e-01	1.54e-01	4.65e-01
SUMOylation of transcription factors	16	3.57e-01	1.33e-01	4.65e-01
PKMTs methylate histone lysines	45	3.58e-01	-7.92e-02	4.65e-01
Cytosolic sulfonation of small molecules	18	3.58e-01	1.25e-01	4.65e-01
DDX58/IFIH1-mediated induction of interferon-alpha/beta	63	3.59e-01	6.68e-02	4.66e-01
Ephrin signaling	18	3.62e-01	1.24e-01	4.70e-01
Molecules associated with elastic fibres	22	3.63e-01	1.12e-01	4.71e-01
Processing of Capped Intron-Containing Pre-mRNA	238	3.66e-01	-3.40e-02	4.73e-01
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	36	3.69e-01	8.65e-02	4.78e-01
Regulation of TP53 Activity through Methylation	19	3.70e-01	-1.19e-01	4.78e-01
Incretin synthesis, secretion, and inactivation	10	3.71e-01	1.63e-01	4.78e-01
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	10	3.71e-01	1.63e-01	4.78e-01
Interconversion of nucleotide di- and triphosphates	27	3.75e-01	9.87e-02	4.83e-01
Protein methylation	15	3.83e-01	1.30e-01	4.93e-01
Chondroitin sulfate/dermatan sulfate metabolism	38	3.91e-01	8.04e-02	5.03e-01
Zinc transporters	14	3.93e-01	1.32e-01	5.05e-01
NOTCH2 intracellular domain regulates transcription	11	3.95e-01	1.48e-01	5.07e-01
IRS-related events triggered by IGF1R	35	3.95e-01	8.30e-02	5.07e-01
mRNA Capping	29	3.97e-01	9.08e-02	5.09e-01
Downstream signaling of activated FGFR4	17	4.02e-01	1.17e-01	5.14e-01
Long-term potentiation	14	4.04e-01	-1.29e-01	5.16e-01
Interleukin receptor SHC signaling	23	4.04e-01	1.00e-01	5.16e-01
Base Excision Repair	58	4.05e-01	-6.32e-02	5.16e-01
Mitochondrial calcium ion transport	22	4.05e-01	1.03e-01	5.16e-01
Transport of inorganic cations/anions and amino acids/oligopeptides	80	4.08e-01	5.35e-02	5.19e-01
Diseases associated with glycosaminoglycan metabolism	26	4.08e-01	9.38e-02	5.19e-01
Regulation of TP53 Activity through Association with Co-factors	12	4.09e-01	-1.38e-01	5.20e-01
SLBP independent Processing of Histone Pre-mRNAs	10	4.10e-01	-1.51e-01	5.20e-01
Adherens junctions interactions	19	4.11e-01	1.09e-01	5.22e-01
HSF1 activation	26	4.12e-01	9.30e-02	5.23e-01
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	13	4.21e-01	1.29e-01	5.34e-01
Activation of BH3-only proteins	30	4.22e-01	8.48e-02	5.34e-01
Post-translational modification: synthesis of GPI-anchored proteins	57	4.25e-01	6.11e-02	5.37e-01
Cell Cycle, Mitotic	502	4.26e-01	2.07e-02	5.38e-01
O-linked glycosylation	83	4.27e-01	-5.05e-02	5.39e-01
Assembly and cell surface presentation of NMDA receptors	18	4.29e-01	-1.08e-01	5.41e-01
Cholesterol biosynthesis	24	4.30e-01	9.30e-02	5.41e-01
Interleukin-20 family signaling	17	4.30e-01	1.11e-01	5.41e-01
Neurotransmitter release cycle	39	4.31e-01	7.29e-02	5.41e-01
Cell-cell junction organization	39	4.31e-01	7.29e-02	5.41e-01
Signaling by WNT in cancer	30	4.31e-01	8.30e-02	5.41e-01
Cyclin D associated events in G1	47	4.33e-01	6.61e-02	5.43e-01
G1 Phase	47	4.33e-01	6.61e-02	5.43e-01
RUNX2 regulates osteoblast differentiation	19	4.36e-01	-1.03e-01	5.45e-01
Class A/1 (Rhodopsin-like receptors)	169	4.36e-01	3.47e-02	5.45e-01
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	37	4.36e-01	7.39e-02	5.45e-01
Signaling by Activin	10	4.40e-01	-1.41e-01	5.49e-01
G1/S-Specific Transcription	29	4.40e-01	-8.28e-02	5.49e-01
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	23	4.43e-01	9.25e-02	5.52e-01
Constitutive Signaling by Aberrant PI3K in Cancer	54	4.44e-01	6.02e-02	5.53e-01
S Phase	161	4.47e-01	-3.48e-02	5.56e-01
Ovarian tumor domain proteases	37	4.53e-01	7.13e-02	5.63e-01
Folding of actin by CCT/TriC	10	4.53e-01	1.37e-01	5.63e-01
Regulation of pyruvate dehydrogenase (PDH) complex	15	4.56e-01	1.11e-01	5.66e-01
Synthesis of IP3 and IP4 in the cytosol	22	4.56e-01	9.17e-02	5.66e-01
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	10	4.57e-01	1.36e-01	5.66e-01
SUMOylation of transcription cofactors	44	4.59e-01	6.45e-02	5.68e-01
Downstream signaling of activated FGFR1	20	4.62e-01	9.49e-02	5.72e-01
Phase 4 - resting membrane potential	10	4.63e-01	1.34e-01	5.72e-01
Role of LAT2/NTAL/LAB on calcium mobilization	74	4.69e-01	-4.87e-02	5.79e-01
Ras activation upon Ca2+ influx through NMDA receptor	15	4.70e-01	-1.08e-01	5.79e-01
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	43	4.72e-01	6.34e-02	5.81e-01
TP53 Regulates Transcription of Cell Cycle Genes	48	4.74e-01	5.97e-02	5.83e-01
Metabolism of vitamins and cofactors	156	4.76e-01	3.31e-02	5.85e-01
The canonical retinoid cycle in rods (twilight vision)	10	4.76e-01	1.30e-01	5.85e-01
APC/C:Cdc20 mediated degradation of Cyclin B	24	4.76e-01	8.40e-02	5.85e-01
MECP2 regulates neuronal receptors and channels	13	4.78e-01	1.14e-01	5.87e-01
Mitotic G1 phase and G1/S transition	148	4.86e-01	3.32e-02	5.94e-01
TNFs bind their physiological receptors	25	4.86e-01	-8.06e-02	5.94e-01
Global Genome Nucleotide Excision Repair (GG-NER)	84	4.86e-01	-4.40e-02	5.94e-01
Cellular hexose transport	15	4.86e-01	-1.04e-01	5.94e-01
DNA Replication Pre-Initiation	83	4.87e-01	4.42e-02	5.94e-01
Telomere Maintenance	80	4.88e-01	-4.48e-02	5.96e-01
Downregulation of SMAD2/3:SMAD4 transcriptional activity	23	4.90e-01	8.31e-02	5.96e-01
Loss of Nlp from mitotic centrosomes	68	4.90e-01	-4.84e-02	5.96e-01
Loss of proteins required for interphase microtubule organization from the centrosome	68	4.90e-01	-4.84e-02	5.96e-01
Reproduction	80	4.93e-01	4.43e-02	5.99e-01
RUNX3 regulates p14-ARF	10	4.97e-01	1.24e-01	6.04e-01
Synthesis of DNA	119	5.06e-01	-3.53e-02	6.14e-01
IRS-mediated signalling	34	5.09e-01	6.55e-02	6.16e-01
Regulation of KIT signaling	15	5.12e-01	9.79e-02	6.20e-01
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	25	5.13e-01	7.56e-02	6.21e-01
SHC-mediated cascade:FGFR4	10	5.17e-01	1.18e-01	6.25e-01
SHC-mediated cascade:FGFR1	12	5.19e-01	1.07e-01	6.27e-01
TP53 Regulates Transcription of DNA Repair Genes	61	5.20e-01	-4.76e-02	6.27e-01
Inactivation, recovery and regulation of the phototransduction cascade	25	5.22e-01	-7.40e-02	6.29e-01
Regulation of FOXO transcriptional activity by acetylation	10	5.27e-01	1.16e-01	6.35e-01
Processing of Intronless Pre-mRNAs	19	5.28e-01	-8.37e-02	6.35e-01
Nicotinamide salvaging	14	5.31e-01	-9.67e-02	6.38e-01
Metabolism of water-soluble vitamins and cofactors	110	5.37e-01	-3.41e-02	6.44e-01
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	91	5.38e-01	-3.74e-02	6.44e-01
Amplification of signal from the kinetochores	91	5.38e-01	-3.74e-02	6.44e-01
Transcriptional Regulation by VENTX	38	5.38e-01	-5.77e-02	6.44e-01
Interleukin-7 signaling	21	5.38e-01	7.76e-02	6.44e-01
Nephrin family interactions	18	5.40e-01	-8.33e-02	6.46e-01
Purine catabolism	16	5.42e-01	8.80e-02	6.48e-01
Caspase-mediated cleavage of cytoskeletal proteins	12	5.47e-01	1.01e-01	6.53e-01
Regulation of TNFR1 signaling	34	5.47e-01	-5.97e-02	6.53e-01
STING mediated induction of host immune responses	15	5.48e-01	8.96e-02	6.53e-01
N-Glycan antennae elongation	13	5.54e-01	-9.48e-02	6.60e-01
MicroRNA (miRNA) biogenesis	24	5.54e-01	6.97e-02	6.60e-01
Acetylcholine Neurotransmitter Release Cycle	11	5.55e-01	-1.03e-01	6.60e-01
mRNA Splicing - Minor Pathway	52	5.56e-01	4.72e-02	6.61e-01
Acyl chain remodelling of PS	14	5.59e-01	9.02e-02	6.63e-01
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	17	5.60e-01	-8.16e-02	6.64e-01
Glutamate and glutamine metabolism	12	5.61e-01	-9.69e-02	6.65e-01
Cargo trafficking to the periciliary membrane	47	5.63e-01	4.88e-02	6.66e-01
PI-3K cascade:FGFR1	12	5.63e-01	9.63e-02	6.66e-01
Endosomal/Vacuolar pathway	12	5.63e-01	-9.63e-02	6.66e-01
PI-3K cascade:FGFR4	10	5.65e-01	1.05e-01	6.67e-01
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	17	5.71e-01	-7.93e-02	6.74e-01
Condensation of Prometaphase Chromosomes	11	5.73e-01	9.81e-02	6.76e-01
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	19	5.78e-01	-7.36e-02	6.81e-01
Mitotic Spindle Checkpoint	108	5.80e-01	-3.08e-02	6.82e-01
FGFR2 alternative splicing	25	5.82e-01	6.37e-02	6.84e-01
TRP channels	19	5.83e-01	-7.28e-02	6.85e-01
PERK regulates gene expression	31	5.86e-01	5.66e-02	6.87e-01
Synthesis of glycosylphosphatidylinositol (GPI)	17	5.89e-01	-7.56e-02	6.91e-01
PI3K Cascade	30	5.90e-01	5.69e-02	6.91e-01
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	27	5.92e-01	5.96e-02	6.93e-01
GPCR ligand binding	235	5.92e-01	2.03e-02	6.93e-01
Meiosis	68	5.93e-01	3.75e-02	6.93e-01
Sema3A PAK dependent Axon repulsion	16	5.96e-01	7.66e-02	6.95e-01
Regulation of RUNX1 Expression and Activity	18	5.97e-01	-7.20e-02	6.96e-01
Basigin interactions	23	6.01e-01	6.31e-02	7.00e-01
Gamma carboxylation, hypusine formation and arylsulfatase activation	34	6.03e-01	5.15e-02	7.02e-01
Synthesis of IP2, IP, and Ins in the cytosol	13	6.04e-01	8.31e-02	7.03e-01
Lysine catabolism	11	6.10e-01	8.87e-02	7.09e-01
WNT ligand biogenesis and trafficking	21	6.10e-01	6.42e-02	7.09e-01
Elevation of cytosolic Ca2+ levels	13	6.11e-01	8.15e-02	7.09e-01
Association of TriC/CCT with target proteins during biosynthesis	37	6.11e-01	4.83e-02	7.09e-01
Ion transport by P-type ATPases	43	6.12e-01	4.47e-02	7.09e-01
Signaling by NTRK3 (TRKC)	16	6.13e-01	7.29e-02	7.10e-01
CD28 co-stimulation	33	6.17e-01	-5.03e-02	7.13e-01
Fertilization	12	6.19e-01	8.29e-02	7.15e-01
Cytosolic sensors of pathogen-associated DNA	62	6.19e-01	3.65e-02	7.15e-01
Mitochondrial protein import	64	6.19e-01	3.59e-02	7.15e-01
Neurexins and neuroligins	37	6.21e-01	-4.70e-02	7.16e-01
mRNA 3’-end processing	56	6.29e-01	-3.73e-02	7.25e-01
Interleukin-37 signaling	19	6.31e-01	6.36e-02	7.26e-01
Prolactin receptor signaling	11	6.33e-01	8.30e-02	7.28e-01
Netrin-1 signaling	40	6.38e-01	4.30e-02	7.33e-01
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	11	6.43e-01	-8.08e-02	7.38e-01
Cell Cycle Checkpoints	260	6.48e-01	1.65e-02	7.43e-01
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)	10	6.50e-01	-8.28e-02	7.45e-01
TICAM1-dependent activation of IRF3/IRF7	12	6.52e-01	7.51e-02	7.47e-01
TP53 Regulates Transcription of Death Receptors and Ligands	12	6.55e-01	7.46e-02	7.49e-01
Formation of Incision Complex in GG-NER	43	6.56e-01	3.93e-02	7.50e-01
Branched-chain amino acid catabolism	21	6.58e-01	-5.57e-02	7.52e-01
TRAF6 mediated IRF7 activation	15	6.59e-01	6.59e-02	7.52e-01
Processing of DNA double-strand break ends	71	6.59e-01	-3.03e-02	7.52e-01
Epigenetic regulation of gene expression	100	6.61e-01	2.54e-02	7.53e-01
Processing of Capped Intronless Pre-mRNA	28	6.63e-01	-4.76e-02	7.55e-01
DNA Replication	126	6.64e-01	-2.24e-02	7.55e-01
Visual phototransduction	60	6.65e-01	3.23e-02	7.56e-01
AURKA Activation by TPX2	71	6.66e-01	-2.96e-02	7.56e-01
Competing endogenous RNAs (ceRNAs) regulate PTEN translation	11	6.66e-01	-7.51e-02	7.56e-01
NOTCH4 Intracellular Domain Regulates Transcription	18	6.67e-01	5.87e-02	7.56e-01
Signaling by FGFR2 in disease	32	6.67e-01	4.39e-02	7.56e-01
Diseases associated with N-glycosylation of proteins	17	6.85e-01	5.69e-02	7.75e-01
G2/M DNA damage checkpoint	68	6.86e-01	-2.84e-02	7.75e-01
Other interleukin signaling	18	6.95e-01	5.34e-02	7.84e-01
RNA Polymerase II Transcription Termination	65	6.95e-01	-2.81e-02	7.84e-01
Gap-filling DNA repair synthesis and ligation in TC-NER	64	6.95e-01	-2.84e-02	7.84e-01
Establishment of Sister Chromatid Cohesion	11	6.97e-01	6.78e-02	7.86e-01
DAP12 signaling	28	6.98e-01	4.23e-02	7.87e-01
Xenobiotics	12	7.03e-01	-6.35e-02	7.91e-01
Signaling by FGFR4 in disease	11	7.05e-01	6.59e-02	7.93e-01
RHO GTPases Activate Formins	117	7.09e-01	2.00e-02	7.96e-01
Binding and Uptake of Ligands by Scavenger Receptors	93	7.09e-01	2.24e-02	7.96e-01
Deactivation of the beta-catenin transactivating complex	36	7.10e-01	3.58e-02	7.96e-01
TP53 Regulates Transcription of Caspase Activators and Caspases	12	7.13e-01	-6.13e-02	7.99e-01
Regulation of Complement cascade	95	7.15e-01	-2.17e-02	8.00e-01
Complement cascade	99	7.15e-01	-2.12e-02	8.00e-01
Synthesis, secretion, and deacylation of Ghrelin	11	7.16e-01	-6.33e-02	8.01e-01
Synthesis of PIPs at the Golgi membrane	16	7.21e-01	5.16e-02	8.05e-01
Phosphorylation of the APC/C	20	7.21e-01	4.61e-02	8.05e-01
Pregnenolone biosynthesis	10	7.23e-01	6.47e-02	8.06e-01
Regulation of PTEN mRNA translation	13	7.23e-01	-5.67e-02	8.06e-01
Receptor-type tyrosine-protein phosphatases	12	7.24e-01	5.89e-02	8.06e-01
RNA Polymerase III Transcription Termination	23	7.25e-01	-4.24e-02	8.06e-01
Processing of SMDT1	15	7.30e-01	5.14e-02	8.12e-01
TNF signaling	43	7.31e-01	3.03e-02	8.12e-01
Glucagon-type ligand receptors	20	7.32e-01	4.42e-02	8.12e-01
Processing and activation of SUMO	10	7.35e-01	6.17e-02	8.15e-01
Cell Cycle	624	7.42e-01	-7.73e-03	8.22e-01
Aberrant regulation of mitotic cell cycle due to RB1 defects	36	7.45e-01	-3.13e-02	8.24e-01
Diseases of mitotic cell cycle	36	7.45e-01	-3.13e-02	8.24e-01
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	20	7.45e-01	-4.20e-02	8.24e-01
Organelle biogenesis and maintenance	268	7.48e-01	-1.14e-02	8.26e-01
Eicosanoid ligand-binding receptors	13	7.48e-01	-5.14e-02	8.26e-01
PI-3K cascade:FGFR2	12	7.50e-01	-5.32e-02	8.26e-01
TNFR1-induced NFkappaB signaling pathway	25	7.50e-01	-3.68e-02	8.26e-01
EML4 and NUDC in mitotic spindle formation	95	7.52e-01	-1.87e-02	8.28e-01
Sulfur amino acid metabolism	22	7.53e-01	3.88e-02	8.28e-01
Signaling by KIT in disease	20	7.56e-01	-4.01e-02	8.30e-01
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	20	7.56e-01	-4.01e-02	8.30e-01
Glutamate Neurotransmitter Release Cycle	20	7.57e-01	-4.00e-02	8.30e-01
Ribosomal scanning and start codon recognition	58	7.59e-01	-2.33e-02	8.32e-01
Signaling by NODAL	13	7.62e-01	-4.86e-02	8.34e-01
TRAF3-dependent IRF activation pathway	13	7.63e-01	4.82e-02	8.36e-01
Signaling by Retinoic Acid	31	7.73e-01	3.00e-02	8.45e-01
Mitochondrial Fatty Acid Beta-Oxidation	36	7.77e-01	2.73e-02	8.49e-01
PIWI-interacting RNA (piRNA) biogenesis	24	7.81e-01	3.28e-02	8.53e-01
Class B/2 (Secretin family receptors)	56	7.84e-01	2.11e-02	8.56e-01
SUMOylation of DNA methylation proteins	16	7.86e-01	-3.91e-02	8.57e-01
HATs acetylate histones	93	7.88e-01	-1.61e-02	8.58e-01
HCMV Early Events	74	7.91e-01	1.78e-02	8.61e-01
Norepinephrine Neurotransmitter Release Cycle	14	7.92e-01	4.07e-02	8.61e-01
Signaling by ROBO receptors	201	7.93e-01	-1.07e-02	8.62e-01
FCERI mediated MAPK activation	90	7.97e-01	1.57e-02	8.65e-01
Voltage gated Potassium channels	25	7.97e-01	2.97e-02	8.65e-01
Deposition of new CENPA-containing nucleosomes at the centromere	40	8.00e-01	2.32e-02	8.66e-01
Nucleosome assembly	40	8.00e-01	2.32e-02	8.66e-01
SHC-mediated cascade:FGFR2	12	8.01e-01	-4.21e-02	8.66e-01
Termination of O-glycan biosynthesis	16	8.02e-01	3.63e-02	8.66e-01
Defective B4GALT7 causes EDS, progeroid type	11	8.02e-01	-4.37e-02	8.66e-01
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	12	8.02e-01	4.18e-02	8.66e-01
Lewis blood group biosynthesis	13	8.04e-01	3.97e-02	8.68e-01
Translation initiation complex formation	58	8.09e-01	-1.83e-02	8.73e-01
IL-6-type cytokine receptor ligand interactions	12	8.11e-01	3.98e-02	8.74e-01
Dual incision in TC-NER	65	8.15e-01	-1.67e-02	8.78e-01
CDC6 association with the ORC:origin complex	11	8.20e-01	-3.95e-02	8.82e-01
Interleukin-2 signaling	11	8.25e-01	3.84e-02	8.87e-01
Inactivation of APC/C via direct inhibition of the APC/C complex	21	8.32e-01	-2.68e-02	8.92e-01
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	21	8.32e-01	-2.68e-02	8.92e-01
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects	17	8.34e-01	-2.94e-02	8.93e-01
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	17	8.34e-01	-2.94e-02	8.93e-01
APC-Cdc20 mediated degradation of Nek2A	26	8.37e-01	2.34e-02	8.96e-01
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	14	8.38e-01	-3.16e-02	8.96e-01
CLEC7A (Dectin-1) induces NFAT activation	11	8.40e-01	-3.52e-02	8.97e-01
N-glycan antennae elongation in the medial/trans-Golgi	21	8.40e-01	-2.54e-02	8.97e-01
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	11	8.42e-01	3.47e-02	8.99e-01
IRF3-mediated induction of type I IFN	12	8.44e-01	-3.29e-02	8.99e-01
Nucleotide-like (purinergic) receptors	13	8.44e-01	3.15e-02	8.99e-01
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	14	8.45e-01	-3.02e-02	9.00e-01
Diseases of glycosylation	108	8.47e-01	-1.07e-02	9.01e-01
Synthesis of PA	32	8.50e-01	1.94e-02	9.01e-01
Metabolism of amino acids and derivatives	326	8.50e-01	-6.08e-03	9.01e-01
Interaction between L1 and Ankyrins	22	8.50e-01	2.33e-02	9.01e-01
Serotonin Neurotransmitter Release Cycle	15	8.50e-01	2.81e-02	9.01e-01
FGFR2 mutant receptor activation	22	8.51e-01	2.31e-02	9.01e-01
G0 and Early G1	27	8.52e-01	2.08e-02	9.01e-01
Regulation of PLK1 Activity at G2/M Transition	86	8.52e-01	-1.16e-02	9.01e-01
GABA synthesis, release, reuptake and degradation	13	8.52e-01	-2.98e-02	9.01e-01
Constitutive Signaling by NOTCH1 HD Domain Mutants	14	8.54e-01	2.85e-02	9.01e-01
Signaling by NOTCH1 HD Domain Mutants in Cancer	14	8.54e-01	2.85e-02	9.01e-01
Vitamin D (calciferol) metabolism	10	8.57e-01	3.29e-02	9.04e-01
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	16	8.58e-01	-2.59e-02	9.04e-01
Activation of SMO	13	8.65e-01	2.73e-02	9.10e-01
EGR2 and SOX10-mediated initiation of Schwann cell myelination	22	8.65e-01	2.10e-02	9.10e-01
Mitochondrial translation termination	91	8.68e-01	-1.01e-02	9.13e-01
KSRP (KHSRP) binds and destabilizes mRNA	17	8.69e-01	-2.32e-02	9.13e-01
RUNX2 regulates bone development	24	8.75e-01	-1.85e-02	9.19e-01
Mitochondrial translation elongation	91	8.78e-01	-9.27e-03	9.22e-01
Signaling by BMP	21	8.81e-01	-1.89e-02	9.23e-01
Nucleotide Excision Repair	110	8.85e-01	-8.00e-03	9.27e-01
Negative regulators of DDX58/IFIH1 signaling	34	8.90e-01	-1.37e-02	9.32e-01
Interleukin-35 Signalling	12	8.91e-01	-2.29e-02	9.32e-01
Regulation of TP53 Expression and Degradation	36	8.93e-01	-1.30e-02	9.33e-01
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	14	8.98e-01	1.99e-02	9.37e-01
Regulation of innate immune responses to cytosolic DNA	14	8.99e-01	1.96e-02	9.38e-01
Methylation	12	8.99e-01	-2.11e-02	9.38e-01
Downstream signaling of activated FGFR2	19	9.03e-01	1.62e-02	9.41e-01
Keratan sulfate biosynthesis	22	9.04e-01	-1.49e-02	9.41e-01
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	20	9.08e-01	-1.50e-02	9.43e-01
Aberrant regulation of mitotic exit in cancer due to RB1 defects	20	9.08e-01	1.49e-02	9.43e-01
Signaling by FGFR3 in disease	13	9.08e-01	1.84e-02	9.43e-01
Signaling by FGFR3 point mutants in cancer	13	9.08e-01	1.84e-02	9.43e-01
G1/S Transition	130	9.10e-01	5.77e-03	9.43e-01
Defective B3GALT6 causes EDSP2 and SEMDJL1	11	9.10e-01	-1.97e-02	9.43e-01
Deadenylation-dependent mRNA decay	53	9.16e-01	-8.41e-03	9.48e-01
DNA Damage Recognition in GG-NER	38	9.16e-01	-9.86e-03	9.48e-01
CTLA4 inhibitory signaling	21	9.19e-01	-1.29e-02	9.50e-01
CRMPs in Sema3A signaling	14	9.19e-01	-1.56e-02	9.50e-01
FRS-mediated FGFR2 signaling	14	9.20e-01	1.56e-02	9.50e-01
Nicotinate metabolism	25	9.21e-01	-1.15e-02	9.50e-01
Resolution of Sister Chromatid Cohesion	104	9.23e-01	-5.49e-03	9.52e-01
Cardiac conduction	86	9.24e-01	5.96e-03	9.52e-01
Transcription of E2F targets under negative control by DREAM complex	19	9.26e-01	1.23e-02	9.53e-01
Anti-inflammatory response favouring Leishmania parasite infection	169	9.27e-01	4.07e-03	9.53e-01
Leishmania parasite growth and survival	169	9.27e-01	4.07e-03	9.53e-01
Transcription-Coupled Nucleotide Excision Repair (TC-NER)	78	9.29e-01	-5.87e-03	9.53e-01
Dopamine Neurotransmitter Release Cycle	20	9.29e-01	1.15e-02	9.53e-01
Lysosphingolipid and LPA receptors	11	9.30e-01	-1.52e-02	9.54e-01
AKT phosphorylates targets in the nucleus	10	9.31e-01	-1.58e-02	9.54e-01
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	59	9.33e-01	-6.36e-03	9.55e-01
FOXO-mediated transcription of cell cycle genes	15	9.36e-01	1.19e-02	9.58e-01
RMTs methylate histone arginines	37	9.37e-01	7.53e-03	9.58e-01
Mitochondrial translation	97	9.40e-01	4.40e-03	9.61e-01
Mitochondrial translation initiation	91	9.42e-01	-4.45e-03	9.61e-01
Defective EXT1 causes exostoses 1, TRPS2 and CHDS	10	9.44e-01	1.29e-02	9.62e-01
Defective EXT2 causes exostoses 2	10	9.44e-01	1.29e-02	9.62e-01
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	31	9.50e-01	6.49e-03	9.67e-01
Regulation of TP53 Degradation	35	9.51e-01	6.03e-03	9.67e-01
SLC transporter disorders	77	9.52e-01	3.97e-03	9.67e-01
mRNA decay by 5’ to 3’ exoribonuclease	15	9.54e-01	-8.64e-03	9.67e-01
Synthesis of PIPs at the early endosome membrane	16	9.54e-01	-8.25e-03	9.67e-01
CASP8 activity is inhibited	11	9.55e-01	-9.91e-03	9.67e-01
Dimerization of procaspase-8	11	9.55e-01	-9.91e-03	9.67e-01
Regulation by c-FLIP	11	9.55e-01	-9.91e-03	9.67e-01
Regulation of FZD by ubiquitination	15	9.56e-01	-8.14e-03	9.68e-01
Tight junction interactions	18	9.57e-01	7.28e-03	9.68e-01
mRNA Splicing - Major Pathway	179	9.58e-01	-2.29e-03	9.68e-01
Collagen chain trimerization	27	9.60e-01	5.54e-03	9.70e-01
PECAM1 interactions	12	9.62e-01	-7.90e-03	9.71e-01
Kinesins	39	9.64e-01	4.16e-03	9.73e-01
Defective B3GAT3 causes JDSSDHD	11	9.69e-01	-6.88e-03	9.76e-01
Inhibition of replication initiation of damaged DNA by RB1/E2F1	13	9.72e-01	5.64e-03	9.79e-01
ATF4 activates genes in response to endoplasmic reticulum stress	26	9.78e-01	-3.15e-03	9.84e-01
Synaptic adhesion-like molecules	15	9.79e-01	3.89e-03	9.85e-01
mRNA Splicing	187	9.80e-01	1.05e-03	9.85e-01
Protein-protein interactions at synapses	58	9.88e-01	1.16e-03	9.92e-01
DCC mediated attractive signaling	13	9.92e-01	1.61e-03	9.96e-01
Glyoxylate metabolism and glycine degradation	24	9.93e-01	-1.02e-03	9.96e-01
Nuclear Receptor transcription pathway	38	9.93e-01	-7.77e-04	9.96e-01
Gene Silencing by RNA	88	9.96e-01	3.02e-04	9.98e-01
Glutathione synthesis and recycling	10	9.99e-01	-2.37e-04	1.00e+00
Ion homeostasis	41	1.00e+00	-1.34e-05	1.00e+00

---

Detailed Gene set reports

Neutrophil degranulation

Neutrophil degranulation

	737
set	Neutrophil degranulation
setSize	457
pANOVA	1.32e-103
s.dist	0.587
p.adjustANOVA	1.8e-100

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A9	9516
S100A12	9515
CTSA	9514
SIRPA	9510
IDH1	9507
RNASE2	9506
MCEMP1	9504
S100A8	9503
CD93	9496
CR1	9486
CREG1	9483
MGST1	9482
BST1	9480
TIMP2	9458
HP	9454
CD36	9444
GCA	9436
PGAM1	9435
SERPINB1	9434
CTSD	9433

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A9	9516
S100A12	9515
CTSA	9514
SIRPA	9510
IDH1	9507
RNASE2	9506
MCEMP1	9504
S100A8	9503
CD93	9496
CR1	9486
CREG1	9483
MGST1	9482
BST1	9480
TIMP2	9458
HP	9454
CD36	9444
GCA	9436
PGAM1	9435
SERPINB1	9434
CTSD	9433
ATP6V0A1	9423
PYGL	9417
LAMTOR1	9411
ITGAM	9398
PKM	9391
DOK3	9388
HK3	9385
SIGLEC9	9383
CKAP4	9370
CTSB	9364
GNS	9360
RAB31	9356
PTAFR	9355
ANPEP	9350
PGM2	9344
QPCT	9327
SDCBP	9311
CDA	9310
GRN	9308
PLD1	9306
QSOX1	9298
FPR1	9295
IMPDH1	9294
CD63	9287
MNDA	9277
VAT1	9276
CYFIP1	9265
LTA4H	9261
PADI2	9257
AGPAT2	9256
ALDOA	9249
MMP8	9232
RAB3D	9207
TOM1	9200
NCSTN	9186
CLEC4D	9185
SLC11A1	9169
SERPINA1	9168
CD55	9145
GPR84	9133
C5AR1	9129
ATP6V0C	9127
CAT	9123
FCN1	9113
FCAR	9111
CRISPLD2	9106
MAPK14	9104
TLR2	9103
TRPM2	9102
CD14	9097
FPR2	9095
VNN1	9092
NFAM1	9086
CYSTM1	9077
OSCAR	9068
GM2A	9059
HBB	9054
MGAM	9050
ATP6V1D	9047
VAPA	9033
CYBB	9031
NEU1	9029
SLC2A3	9021
BRI3	9017
APAF1	9015
GYG1	9013
PRKCD	9008
ALOX5	9001
RETN	8998
CTSZ	8975
S100A11	8946
ITGB2	8942
PRDX6	8937
SERPINB10	8933
RAB10	8926
SELL	8912
CYB5R3	8903
LILRB3	8871
FCGR2A	8845
RAC1	8793
ADAM10	8791
LAMP2	8786
HEXB	8776
ARG1	8759
LGALS3	8752
GSN	8749
RAB7A	8742
TNFAIP6	8738
AMPD3	8732
GLB1	8725
OLFM4	8724
ARPC5	8686
DNAJC5	8679
LRG1	8674
FTL	8665
ALDH3B1	8663
RAB5C	8655
PYCARD	8638
PDXK	8635
DNASE1L1	8632
SNAP23	8628
TOLLIP	8572
GLA	8570
CAPN1	8563
ANXA2	8544
CD68	8533
ASAH1	8529
MMP25	8515
ALAD	8514
DERA	8500
RHOG	8487
PSMB7	8485
FGR	8478
HPSE	8476
CLEC5A	8473
PLAC8	8452
P2RX1	8436
DNAJC3	8435
CEACAM1	8429
PLAUR	8424
PNP	8419
RAB27A	8411
HEBP2	8398
ATP11A	8394
CTSS	8372
TMBIM1	8361
CPPED1	8357
CD44	8333
S100P	8331
RHOA	8319
FUCA2	8304
ACAA1	8292
CAB39	8276
DNAJC13	8263
GMFG	8259
MOSPD2	8252
ARL8A	8249
PRCP	8218
ADGRG3	8204
SIGLEC5	8161
IQGAP1	8152
RAB6A	8148
ATG7	8134
RAB3A	8133
FCER1G	8131
CAP1	8111
HSPA1A	8071
CD33	8069
PLEKHO2	8059
LILRB2	8057
ANO6	8048
TMEM30A	8036
ATP6AP2	8034
C3AR1	8012
ORM1	7971
GAA	7968
COMMD9	7967
PSEN1	7961
COTL1	7933
PGLYRP1	7910
CMTM6	7891
CD53	7884
ACTR2	7870
KCMF1	7869
PECAM1	7855
PSMD6	7846
SIRPB1	7843
TRAPPC1	7806
RAB18	7801
PGRMC1	7795
PTPRJ	7783
LCN2	7755
DBNL	7749
GLIPR1	7739
DOCK2	7725
GUSB	7723
CANT1	7707
NCKAP1L	7673
LAMP1	7631
UNC13D	7607
ACTR10	7605
LAMTOR3	7574
ARSB	7572
LAMTOR2	7567
CRISP3	7552
TYROBP	7539
MAPK1	7493
ROCK1	7489
RNASE3	7471
FOLR3	7451
CFP	7445
MPO	7437
OSTF1	7426
NAPRT	7412
PSMD2	7411
FUCA1	7408
MANBA	7386
ITGAX	7337
VCL	7328
COPB1	7321
ELANE	7320
RAP1A	7305
GDI2	7282
AP2A2	7257
PSMD1	7241
TUBB4B	7240
LYZ	7213
TCIRG1	7188
LAIR1	7184
IGF2R	7149
PSAP	7145
GALNS	7102
RAB14	7095
NBEAL2	7086
SURF4	7058
MVP	7053
TSPAN14	6971
ATP8B4	6970
PAFAH1B2	6942
DYNC1LI1	6941
DDOST	6931
CYBA	6922
METTL7A	6920
ERP44	6905
CSTB	6904
VCP	6886
MAN2B1	6878
CXCR1	6864
CEACAM3	6838
PRTN3	6762
AP1M1	6711
STOM	6704
RAB5B	6690
YPEL5	6684
BPI	6666
CD58	6647
CNN2	6645
DDX3X	6614
IQGAP2	6599
PSMD12	6556
CCT8	6552
HSPA6	6514
AOC1	6509
HSPA1B	6470
ARMC8	6398
SNAP29	6390
CTSH	6360
TICAM2	6335
SRP14	6320
LTF	6306
GPI	6284
NFKB1	6277
ARHGAP9	6256
PSMD11	6231
GGH	6205
C6orf120	6192
TCN1	6182
DEGS1	6169
VPS35L	6118
ITGAV	6106
PTPN6	6096
NDUFC2	6093
ATP11B	6064
DEFA1	6061
DEFA4	6057
TNFRSF1B	6045
PPBP	6042
FABP5	6021
CHIT1	6012
PSMD7	5963
DYNLL1	5952
PSMD13	5948
RNASET2	5922
PDAP1	5908
CPNE3	5872
IST1	5862
CXCR2	5861
CD59	5859
SERPINB6	5854
PGM1	5843
CXCL1	5824
PTX3	5797
BIN2	5745
ADAM8	5634
A1BG	5559
FAF2	5554
STBD1	5544
AZU1	5507
NPC2	5458
XRCC5	5384
NRAS	5363
RAB24	5354
PSMA2	5339
TARM1	5307
DGAT1	5306
SLPI	5298
VAMP8	5218
PTPRN2	5183
ACLY	5159
CTSG	5115
SIGLEC14	5087
CEACAM8	4956
HVCN1	4912
PLAU	4903
FTH1	4902
STING1	4791
CAMP	4785
ABCA13	4768
PSMD3	4618
RAP2C	4599
KRT1	4537
CLEC12A	4535
CEACAM6	4509
DYNLT1	4450
FCGR3B	4313
B4GALT1	4292
GHDC	4158
GOLGA7	4055
CSNK2B	3969
SLC15A4	3724
STK11IP	3586
ARSA	3486
PSMB1	3374
SLCO4C1	3212
RAP1B	3206
RAB4B	3137
SLC44A2	2700
MAGT1	2613
PSMD14	2611
PSMC2	2598
OLR1	2486
CD177	2457
KPNB1	2430
MS4A3	2361
CTSC	2326
MLEC	2322
PTPRC	2240
CST3	2206
SLC2A5	2044
SVIP	2035
CFD	1984
PSMC3	1976
GSDMD	1955
SCAMP1	1868
HGSNAT	1867
NME2	1850
MMP9	1690
HSP90AA1	1326
NHLRC3	1276
HLA-C	1018
APEH	997
MME	916
NFASC	866
FGL2	675
HLA-B	649
RAB44	573
PYGB	492
TMEM179B	449
ADGRE3	408
TXNDC5	393
EEF2	306
GSTP1	135
FRK	-24
KCNAB2	-101
PRDX4	-144
HMGB1	-252
PIGR	-487
CHI3L1	-650
RAP2B	-771
DIAPH1	-854
COMMD3	-1363
DSP	-1812
LRRC7	-1966
ILF2	-1979
UBR4	-2086
CD300A	-2133
ORM2	-2564
ADGRE5	-2571
HLA-A	-2573
APRT	-2766
AGL	-3136
PFKL	-3277
CPNE1	-3397
ALDOC	-3438
SLC27A2	-3831
MIF	-3863
HLA-H	-3889
STK10	-3898
PA2G4	-3916
XRCC6	-4471
DPP7	-4586
SYNGR1	-4629
AGA	-4632
EPX	-4838
EEF1A1	-5087
JUP	-5353
PSMA5	-6053
RAB9B	-6552
CAND1	-6554
PPIA	-6766
HSP90AB1	-6863
B2M	-6920
PTGES2	-6926
DSC1	-6927
TUBB	-6956
HRNR	-7349
BST2	-7385
LPCAT1	-7428
PTPRB	-7607
DYNC1H1	-7685
HUWE1	-7977
CDK13	-8392
CCT2	-8825
PPIE	-9002
CRACR2A	-9069
TMEM63A	-9137
CEP290	-9182
ENPP4	-9583
IMPDH2	-9916
ORMDL3	-9997
ATAD3B	-10079
ACTR1B	-10514
TMC6	-10606
DSN1	-10773
ITGAL	-10847
HSPA8	-10922
SPTAN1	-11426
FRMPD3	-11469
NIT2	-11695
RAB37	-11793
CLEC4C	-11809
HMOX2	-11819
ATP8A1	-11842
TBC1D10C	-11861
CD47	-12114
C3	-12262
RHOF	-12344

---

Innate Immune System

Innate Immune System

	537
set	Innate Immune System
setSize	967
pANOVA	5.85e-84
s.dist	0.367
p.adjustANOVA	3.99e-81

Top enriched genes

Top 20 genes

GeneID	Gene Rank
WASF1	9520
S100A9	9516
S100A12	9515
CTSA	9514
SIRPA	9510
IDH1	9507
RNASE2	9506
MCEMP1	9504
S100A8	9503
CD93	9496
CR1	9486
CREG1	9483
MGST1	9482
BST1	9480
TIMP2	9458
HP	9454
CCR2	9449
CD36	9444
GCA	9436
PGAM1	9435

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
WASF1	9520
S100A9	9516
S100A12	9515
CTSA	9514
SIRPA	9510
IDH1	9507
RNASE2	9506
MCEMP1	9504
S100A8	9503
CD93	9496
CR1	9486
CREG1	9483
MGST1	9482
BST1	9480
TIMP2	9458
HP	9454
CCR2	9449
CD36	9444
GCA	9436
PGAM1	9435
SERPINB1	9434
CTSD	9433
PRKACA	9429
ATP6V0A1	9423
PYGL	9417
LAMTOR1	9411
NLRC4	9406
ITGAM	9398
PKM	9391
DOK3	9388
HK3	9385
SIGLEC9	9383
CLU	9371
CKAP4	9370
CTSB	9364
GNS	9360
RASGRP4	9359
RAB31	9356
PTAFR	9355
NKIRAS2	9353
ANPEP	9350
SIGLEC15	9348
PGM2	9344
TLR8	9343
QPCT	9327
FCGR1A	9323
SDCBP	9311
CDA	9310
GRN	9308
PLD1	9306
GRB2	9304
ATP6V1A	9302
QSOX1	9298
FPR1	9295
IMPDH1	9294
CD63	9287
DUSP3	9280
MNDA	9277
VAT1	9276
NCF4	9268
CYFIP1	9265
LTA4H	9261
ARPC1B	9259
PADI2	9257
AGPAT2	9256
ALDOA	9249
ATP6V0D1	9245
MMP8	9232
RAB3D	9207
TLR5	9201
TOM1	9200
NCF2	9190
UBE2D1	9187
NCSTN	9186
CLEC4D	9185
APP	9177
SLC11A1	9169
SERPINA1	9168
SIGLEC16	9164
CD55	9145
GPR84	9133
C5AR1	9129
ATP6V0C	9127
CAT	9123
FCN1	9113
FCAR	9111
IRAK3	9107
CRISPLD2	9106
MAPK14	9104
TLR2	9103
TRPM2	9102
CD14	9097
FPR2	9095
VNN1	9092
NFAM1	9086
CYSTM1	9077
SYK	9076
OSCAR	9068
MAP2K1	9063
GM2A	9059
ATP6V1B2	9057
HBB	9054
MGAM	9050
ATP6V1D	9047
PIK3CB	9038
VAPA	9033
CYBB	9031
NEU1	9029
SLC2A3	9021
BRI3	9017
TLR4	9016
APAF1	9015
GYG1	9013
ACTB	9011
PRKCD	9008
ALOX5	9001
RETN	8998
HCK	8976
CTSZ	8975
MAPK3	8953
S100A11	8946
ITGB2	8942
PRDX6	8937
SERPINB10	8933
TLR1	8932
RAB10	8926
MYO10	8918
SELL	8912
CRK	8906
CYB5R3	8903
NLRP3	8901
ARPC1A	8894
MAP2K6	8887
LILRB3	8871
FCGR2A	8845
TLR6	8840
LAT2	8799
LY96	8795
RAC1	8793
ADAM10	8791
LAMP2	8786
HEXB	8776
ARG1	8759
LGALS3	8752
C1QC	8750
GSN	8749
MAP2K3	8748
ALPK1	8745
RAB7A	8742
TNFAIP6	8738
AMPD3	8732
GLB1	8725
OLFM4	8724
BCL2L1	8700
ARPC5	8686
DNAJC5	8679
LRG1	8674
FTL	8665
ALDH3B1	8663
RAB5C	8655
UBE2D3	8640
PYCARD	8638
PDXK	8635
DNASE1L1	8632
SNAP23	8628
CDC34	8611
MEFV	8605
ATP6V0B	8598
CAPZA2	8597
ATP6V0E1	8596
TOLLIP	8572
GLA	8570
CAPN1	8563
ACTG1	8562
WAS	8560
RNF135	8556
ANXA2	8544
ATP6V1C1	8539
CD68	8533
ASAH1	8529
MMP25	8515
ALAD	8514
DERA	8500
RHOG	8487
PSMB7	8485
FGR	8478
HPSE	8476
CLEC5A	8473
PLAC8	8452
NOD2	8442
P2RX1	8436
DNAJC3	8435
CEACAM1	8429
PLAUR	8424
PNP	8419
RAB27A	8411
PSMD4	8402
HEBP2	8398
ATP11A	8394
MAPKAPK3	8382
CTSS	8372
WASF2	8369
TMBIM1	8361
CPPED1	8357
C1QB	8337
CD44	8333
S100P	8331
CLEC4E	8324
RHOA	8319
PELI2	8314
FUCA2	8304
ACAA1	8292
TXN	8285
ARPC3	8277
CAB39	8276
DNAJC13	8263
CLEC4A	8260
GMFG	8259
MOSPD2	8252
PSME3	8251
ARL8A	8249
PPP2CA	8234
PAK1	8230
TRIM25	8226
PRCP	8218
ADGRG3	8204
C5AR2	8187
CFL1	8186
PAK2	8185
PPP3R1	8175
SIGLEC5	8161
IQGAP1	8152
RAB6A	8148
MYD88	8136
CAPZA1	8135
ATG7	8134
RAB3A	8133
FCER1G	8131
CAP1	8111
PSMB5	8101
GAB2	8099
HSPA1A	8071
CD33	8069
ATP6V1H	8064
PLEKHO2	8059
LILRB2	8057
ANO6	8048
TMEM30A	8036
ATP6V1E1	8035
ATP6AP2	8034
C3AR1	8012
MEF2A	8009
ORM1	7971
GAA	7968
COMMD9	7967
CHUK	7966
PSEN1	7961
COTL1	7933
PGLYRP1	7910
VAV1	7896
CMTM6	7891
CD53	7884
RAF1	7879
ACTR2	7870
KCMF1	7869
PECAM1	7855
PSMD6	7846
SIRPB1	7843
PSTPIP1	7841
NLRX1	7826
ACTR3	7818
LYN	7809
ICAM3	7808
TRAPPC1	7806
RAB18	7801
PGRMC1	7795
PTPRJ	7783
UBA3	7767
CNPY3	7761
PROS1	7758
LCN2	7755
DBNL	7749
GLIPR1	7739
DOCK2	7725
GUSB	7723
PELI3	7716
PPP2CB	7712
CANT1	7707
RPS6KA1	7695
CASP9	7685
NCKAP1L	7673
LY86	7667
LAMP1	7631
PSMD9	7620
UNC13D	7607
ACTR10	7605
LAMTOR3	7574
ARSB	7572
LAMTOR2	7567
POLR2E	7563
CRISP3	7552
TEC	7549
TYROBP	7539
CDC42	7537
ARPC4	7516
TANK	7502
MAPK1	7493
ROCK1	7489
UBE2M	7477
RNASE3	7471
NCKAP1	7462
FOLR3	7451
CFP	7445
MPO	7437
OSTF1	7426
NAPRT	7412
PSMD2	7411
FUCA1	7408
ARPC2	7390
MANBA	7386
PLD3	7364
ITGAX	7337
NCF1	7334
PSMA1	7329
VCL	7328
COPB1	7321
ELANE	7320
DOCK1	7314
RAP1A	7305
GDI2	7282
AP2A2	7257
PSMD1	7241
TUBB4B	7240
LYZ	7213
BTK	7206
TCIRG1	7188
CD300LB	7186
LAIR1	7184
PLD2	7180
PSMB3	7171
IGF2R	7149
PSAP	7145
MAVS	7124
GALNS	7102
PSMA7	7096
RAB14	7095
NBEAL2	7086
ABI1	7082
SURF4	7058
MVP	7053
DNM3	7045
BRK1	7032
PSMC1	7021
TREM1	7009
PPP3CB	7005
TSPAN14	6971
ATP8B4	6970
TAB2	6964
PAFAH1B2	6942
DYNC1LI1	6941
DDOST	6931
CYBA	6922
METTL7A	6920
ERP44	6905
CSTB	6904
VCP	6886
UBE2K	6884
MAN2B1	6878
MAP2K4	6866
CXCR1	6864
CEACAM3	6838
RNASE6	6837
PSMB6	6813
WASF3	6808
NFKBIA	6807
PRTN3	6762
CD300E	6742
CLEC6A	6730
PELI1	6715
AP1M1	6711
STOM	6704
MYO5A	6693
RAB5B	6690
MYH9	6685
YPEL5	6684
BPI	6666
PSMF1	6659
CARD9	6648
CD58	6647
CNN2	6645
UBB	6639
PSMC6	6635
C1QA	6626
DDX3X	6614
IQGAP2	6599
MUC1	6573
POLR1D	6566
PSMD12	6556
CCT8	6552
HSPA6	6514
AOC1	6509
LPO	6502
HSPA1B	6470
AHCYL1	6456
CGAS	6444
MYO9B	6424
CTNNB1	6408
ARMC8	6398
SNAP29	6390
CTSH	6360
TICAM2	6335
SRP14	6320
TICAM1	6307
LTF	6306
LRRFIP1	6302
GPI	6284
NFKB1	6277
PANX1	6267
ELMO1	6258
ARHGAP9	6256
PSMD11	6231
PPP3CA	6217
GGH	6205
FBXW11	6196
C6orf120	6192
TCN1	6182
DEGS1	6169
MAP3K8	6160
DTX4	6156
PDPK1	6136
IRAK1	6131
EP300	6129
VPS35L	6118
ITGAV	6106
PTPN6	6096
NDUFC2	6093
DNM2	6089
ATP11B	6064
DEFA1	6061
DEFA4	6057
TNFRSF1B	6045
PPBP	6042
TAX1BP1	6031
FABP5	6021
CHIT1	6012
PSMA6	5970
PSMD7	5963
DYNLL1	5952
PSMD13	5948
RNASET2	5922
CASP4	5919
PDAP1	5908
STAT6	5884
ATP6V1F	5878
CPNE3	5872
IST1	5862
CXCR2	5861
CD59	5859
SERPINB6	5854
CD46	5851
BCL10	5849
PGM1	5843
ITPR2	5842
CXCL1	5824
PTX3	5797
PSMD8	5757
BIN2	5745
ATP6V1E2	5730
WIPF2	5713
ATF1	5706
TAB1	5681
FADD	5641
TIRAP	5640
UBE2V1	5637
ADAM8	5634
CLEC7A	5608
A1BG	5559
FAF2	5554
TNIP2	5552
STBD1	5544
AZU1	5507
FOS	5460
NPC2	5458
DEFA3	5385
XRCC5	5384
IKBKG	5377
NRAS	5363
RAB24	5354
PSMA2	5339
PTPN11	5314
TARM1	5307
DGAT1	5306
POLR2L	5305
SLPI	5298
TKFC	5285
PCBP2	5283
PRKCSH	5220
VAMP8	5218
PTPRN2	5183
RAC2	5163
ACLY	5159
MAP3K1	5121
CTSG	5115
SIGLEC14	5087
CTSK	5059
TIFA	5046
PIK3R2	5010
PLCG2	5006
CEACAM8	4956
ECSIT	4918
HVCN1	4912
PLAU	4903
FTH1	4902
VAV3	4894
CRCP	4826
IL1B	4807
STING1	4791
CAMP	4785
ABCA13	4768
C4BPA	4735
IKBKE	4715
BIRC2	4692
GRAP2	4690
LIMK1	4679
UBE2D2	4657
EEA1	4641
PIK3CA	4629
PSMD3	4618
POLR2F	4604
RAP2C	4599
PPP2R1A	4589
KRT1	4537
CLEC12A	4535
CEACAM6	4509
C4A	4466
PTK2	4462
DYNLT1	4450
UBC	4439
ELMO2	4397
DUSP6	4357
SEM1	4348
ATOX1	4338
MAPK10	4325
FCGR3B	4313
B4GALT1	4292
SKP1	4287
CTSL	4231
CASP1	4224
RIPK3	4217
UNC93B1	4170
SHC1	4161
GHDC	4158
CPN2	4118
PSMB2	4084
GOLGA7	4055
MAPKAPK2	4054
CSNK2B	3969
C5	3954
SOCS1	3947
ATP6V1G1	3931
C2	3925
C4B	3922
MAPK13	3865
MAPK11	3826
SLC15A4	3724
JUN	3722
RELB	3721
KRAS	3702
DNM1	3587
STK11IP	3586
ARSA	3486
P2RX7	3475
PSMD5	3426
DDX41	3424
CREBBP	3423
PSMB1	3374
MYO1C	3310
TBK1	3229
SLCO4C1	3212
RAP1B	3206
TAB3	3160
RAB4B	3137
RPS6KA2	3087
PI3	3023
RPS6KA3	2973
SLC44A2	2700
MAGT1	2613
PSMD14	2611
PSMC2	2598
PSMB4	2523
OLR1	2486
CD177	2457
KPNB1	2430
TRIM21	2428
PPP2R5D	2421
MAP3K7	2395
MS4A3	2361
CTSC	2326
MLEC	2322
EPPIN	2251
PTPRC	2240
CST3	2206
ATF2	2085
HSP90B1	2059
SLC2A5	2044
SVIP	2035
CFD	1984
PSMC3	1976
GSDMD	1955
UBE2N	1936
SCAMP1	1868
HGSNAT	1867
NME2	1850
MMP9	1690
MAP2K7	1654
PIK3C3	1619
PSMD10	1559
SUGT1	1544
ATG5	1398
NOS1	1365
HSP90AA1	1326
ITCH	1318
AGER	1294
VRK3	1281
NHLRC3	1276
UBA52	1121
ELK1	1040
RIPK2	1025
DHX9	1019
HLA-C	1018
APEH	997
MME	916
NFASC	866
ATP7A	694
FGL2	675
HLA-B	649
RAB44	573
WIPF1	569
PYGB	492
TMEM179B	449
ADGRE3	408
TXNDC5	393
NKIRAS1	375
IGHV1-2	360
NCKIPSD	328
EEF2	306
WASL	299
IGHV2-5	230
ABL1	226
GSTP1	135
IFI16	105
IGHV3-53	103
FRK	-24
KCNAB2	-101
PRDX4	-144
NFKBIB	-152
BAIAP2	-215
TRAF6	-229
PPP2R1B	-241
HMGB1	-252
MEF2C	-293
IGHV3-7	-441
PIGR	-487
CD180	-600
PSMA4	-616
IGHV1-46	-618
TLR7	-625
CHI3L1	-650
IGHV3-48	-668
ATG12	-770
RAP2B	-771
IGKV3-11	-781
DIAPH1	-854
PSMC5	-863
IGKV1-39	-989
IGLV7-46	-1016
MAPK12	-1074
LCP2	-1156
NFKB2	-1165
IGKV1-5	-1184
TREX1	-1198
IGLV2-8	-1294
IGKV5-2	-1298
IGHV3-23	-1317
MAPK7	-1337
COMMD3	-1363
CREB1	-1378
IGHV3-13	-1443
IGLV2-18	-1524
IGKV1-16	-1528
IGLV4-69	-1559
IGKV1D-39	-1574
AIM2	-1718
POLR2K	-1783
RELA	-1803
DSP	-1812
IGHV1-69	-1822
IGLV10-54	-1884
LRRC7	-1966
ILF2	-1979
IGLV1-36	-2030
IGKV2-30	-2045
VTN	-2046
NOS3	-2059
CALM1	-2081
UBR4	-2086
IGLV7-43	-2089
IGLV3-19	-2111
CD300A	-2133
IGHV3-11	-2134
MUCL1	-2211
ATP6V1C2	-2219
PGLYRP2	-2281
IGKV3-15	-2297
C1S	-2420
IGKV1-33	-2424
C4BPB	-2452
POLR3K	-2467
CASP2	-2471
IGHV3-30	-2484
IGKV4-1	-2532
ORM2	-2564
ADGRE5	-2571
HLA-A	-2573
APRT	-2766
IGKV1-17	-2871
IGLV2-23	-2878
IGLV6-57	-2885
IGHV4-59	-2892
IGLV2-11	-2905
POLR2H	-2942
TLR10	-2961
MUC6	-2977
IGHV3-33	-2988
IGHV4-34	-3016
CTSV	-3036
PSMB8	-3076
IGKV3-20	-3085
AGL	-3136
IGHV2-70	-3138
PIN1	-3188
MUC4	-3191
DUSP7	-3211
IGLV1-44	-3258
PFKL	-3277
HRAS	-3382
CPNE1	-3397
ALDOC	-3438
CASP10	-3446
HTN1	-3453
IGHG3	-3481
CFB	-3518
AAMP	-3636
SLC27A2	-3831
CD19	-3843
MIF	-3863
HLA-H	-3889
IGKV3D-20	-3894
STK10	-3898
PA2G4	-3916
VAV2	-4055
PIK3R4	-4062
MUC16	-4104
IGLV3-1	-4159
PAK3	-4184
CR2	-4340
HLA-E	-4415
IGKC	-4428
XRCC6	-4471
RBSN	-4542
IGHV4-39	-4582
DPP7	-4586
MUC5B	-4613
SYNGR1	-4629
AGA	-4632
LGMN	-4644
LEAP2	-4703
BCL2	-4704
IGLV3-21	-4735
IGLV1-40	-4788
EPX	-4838
BTRC	-4924
IGLV3-25	-4933
IGLV1-51	-4956
EEF1A1	-5087
IGHE	-5123
OTUD5	-5132
POLR3F	-5191
DHX36	-5245
IGLC7	-5281
PSMA3	-5285
CLEC10A	-5299
JUP	-5353
MASP2	-5358
IKBKB	-5386
POLR3G	-5401
CD4	-5406
IGLV8-61	-5427
IGKV1-12	-5446
S100B	-5457
IGLC3	-5477
IGLC2	-5510
CFH	-5562
TRAF3	-5576
IGKV2D-28	-5634
SOS1	-5700
PSMB10	-5735
IGKV2-28	-5808
IGLV5-45	-5869
IGLV3-27	-5874
MUC20	-5962
TLR9	-5999
IGLV1-47	-6018
PSMA5	-6053
PSME4	-6087
IGLC1	-6157
IGHG1	-6201
DUSP4	-6287
PDZD11	-6288
NLRP1	-6332
NF2	-6540
RAB9B	-6552
CAND1	-6554
PPIA	-6766
HSP90AB1	-6863
ITLN1	-6873
IGHG4	-6911
B2M	-6920
PTGES2	-6926
DSC1	-6927
RPS27A	-6938
TUBB	-6956
SIKE1	-7060
MAPK9	-7068
IGHG2	-7250
POLR3A	-7324
HRNR	-7349
POLR3B	-7356
IGLV3-12	-7358
BST2	-7385
POLR3C	-7421
LPCAT1	-7428
PLPP5	-7430
POLR3GL	-7481
UBA7	-7558
PSMA8	-7606
PTPRB	-7607
ITPR1	-7629
DYNC1H1	-7685
CCR6	-7862
MRE11	-7923
HUWE1	-7977
PRKCE	-8001
S100A1	-8108
IGLV2-14	-8345
CDK13	-8392
KIR2DS4	-8405
IRF3	-8517
RASGRP2	-8529
IRF7	-8657
TRIM56	-8736
SRC	-8820
CCT2	-8825
PPIE	-9002
CRACR2A	-9069
PSMC4	-9127
TMEM63A	-9137
CD209	-9143
NFATC1	-9147
CEP290	-9182
CD81	-9227
CYLD	-9359
MAPK8	-9428
PIK3R1	-9505
ATP6V1G2	-9515
IRAK2	-9548
KLRC2	-9578
ENPP4	-9583
TXNIP	-9600
C1R	-9669
IMPDH2	-9916
PSME1	-9991
ORMDL3	-9997
ATAD3B	-10079
PRKDC	-10219
ITPR3	-10308
POLR3H	-10310
NLRC5	-10323
PSME2	-10336
CYFIP2	-10367
ACTR1B	-10514
RNF216	-10540
TMC6	-10606
MUC12	-10704
SIGIRR	-10752
DSN1	-10773
ITGAL	-10847
POLR1C	-10899
ABI2	-10915
MALT1	-10920
HSPA8	-10922
TNFAIP3	-10950
RIPK1	-11074
MS4A2	-11106
PLCG1	-11120
BIRC3	-11125
RNF125	-11190
SERPING1	-11197
ITK	-11223
UBE2L6	-11293
PSMB9	-11324
CUL1	-11330
IFIH1	-11332
CASP8	-11336
POLR3E	-11383
SPTAN1	-11426
GNLY	-11428
NCK1	-11454
FRMPD3	-11469
TRIM32	-11493
TLR3	-11525
CD3G	-11526
ATP6V0E2	-11555
RPS6KA5	-11594
C8G	-11641
FYN	-11675
TXK	-11676
LAT	-11694
NIT2	-11695
MAP3K14	-11702
TRAF2	-11746
POLR3D	-11777
RAB37	-11793
CLEC4C	-11809
HMOX2	-11819
DHX58	-11824
LCK	-11838
GZMM	-11840
ATP8A1	-11842
TBC1D10C	-11861
DDX58	-11950
PRKACB	-11959
RASGRP1	-11974
FCGR3A	-12005
ICAM2	-12026
ISG15	-12032
FCER1A	-12046
KLRD1	-12062
CD47	-12114
PLA2G6	-12122
PRKCQ	-12127
SARM1	-12134
YES1	-12142
CARD11	-12160
NFATC3	-12177
NLRC3	-12203
ATP6V0A2	-12211
PTPN4	-12220
HERC5	-12225
C3	-12262
NOD1	-12263
NFATC2	-12294
KLRK1	-12309
ZBP1	-12325
RHOF	-12344
CD247	-12345
PLD4	-12365

---

Immune System

Immune System

	520
set	Immune System
setSize	1893
pANOVA	3.24e-46
s.dist	0.198
p.adjustANOVA	1.48e-43

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CSF2RA	9526
WASF1	9520
S100A9	9516
S100A12	9515
CTSA	9514
SIRPA	9510
IDH1	9507
RNASE2	9506
MCEMP1	9504
S100A8	9503
VAMP7	9499
CD93	9496
CR1	9486
CREG1	9483
MGST1	9482
BST1	9480
SOCS3	9476
TIMP2	9458
TALDO1	9456
HP	9454

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CSF2RA	9526.0
WASF1	9520.0
S100A9	9516.0
S100A12	9515.0
CTSA	9514.0
SIRPA	9510.0
IDH1	9507.0
RNASE2	9506.0
MCEMP1	9504.0
S100A8	9503.0
VAMP7	9499.0
CD93	9496.0
CR1	9486.0
CREG1	9483.0
MGST1	9482.0
BST1	9480.0
SOCS3	9476.0
TIMP2	9458.0
TALDO1	9456.0
HP	9454.0
CCR2	9449.0
CD36	9444.0
SERPINB2	9438.0
GCA	9436.0
PGAM1	9435.0
SERPINB1	9434.0
CTSD	9433.0
PRKACA	9429.0
ATP6V0A1	9423.0
PYGL	9417.0
FBXO9	9416.0
LAMTOR1	9411.0
FBXL5	9410.0
NLRC4	9406.0
ITGAM	9398.0
LTBR	9395.0
VIM	9394.0
PKM	9391.0
DOK3	9388.0
HK3	9385.0
SIGLEC9	9383.0
IL1RN	9381.0
CA1	9380.0
CLU	9371.0
CKAP4	9370.0
CTSB	9364.0
GNS	9360.0
RASGRP4	9359.0
RAB31	9356.0
PTAFR	9355.0
NKIRAS2	9353.0
ANPEP	9350.0
SIGLEC15	9348.0
MAOA	9346.0
LMNB1	9345.0
PGM2	9344.0
TLR8	9343.0
QPCT	9327.0
FCGR1A	9323.0
SDCBP	9311.0
CDA	9310.0
GRN	9308.0
PLD1	9306.0
GRB2	9304.0
ATP6V1A	9302.0
QSOX1	9298.0
FPR1	9295.0
IMPDH1	9294.0
CD63	9287.0
AP1S1	9286.0
DUSP3	9280.0
MNDA	9277.0
VAT1	9276.0
IFNGR1	9273.0
IL10	9272.0
TNFRSF1A	9270.0
NCF4	9268.0
CYFIP1	9265.0
LTA4H	9261.0
ARPC1B	9259.0
PADI2	9257.0
AGPAT2	9256.0
LILRA6	9250.0
ALDOA	9249.0
ATP6V0D1	9245.0
IFNGR2	9238.0
MMP8	9232.0
RAB3D	9207.0
TLR5	9201.0
TOM1	9200.0
IL17RA	9194.0
NCF2	9190.0
IL1R2	9188.0
UBE2D1	9187.0
NCSTN	9186.0
CLEC4D	9185.0
APP	9177.0
BCL6	9175.0
KLHL2	9174.0
UBE2J1	9170.0
SLC11A1	9169.0
SERPINA1	9168.0
SIGLEC16	9164.0
IL10RB	9163.0
DCTN2	9157.0
SPTB	9154.0
CD55	9145.0
GPR84	9133.0
C5AR1	9129.0
ATP6V0C	9127.0
CAT	9123.0
FCN1	9113.0
FCAR	9111.0
IRAK3	9107.0
CRISPLD2	9106.0
MAPK14	9104.0
TLR2	9103.0
TRPM2	9102.0
CD14	9097.0
FPR2	9095.0
VNN1	9092.0
NFAM1	9086.0
GSTO1	9084.0
LILRA5	9081.0
CYSTM1	9077.0
SYK	9076.0
OSCAR	9068.0
LILRA2	9066.0
ARF1	9064.0
MAP2K1	9063.0
GM2A	9059.0
ATP6V1B2	9057.0
FKBP1A	9056.0
HBB	9054.0
FCGR1B	9053.0
MGAM	9050.0
ATP6V1D	9047.0
PIK3CB	9038.0
RAP1GAP	9037.0
STXBP2	9035.0
VAPA	9033.0
CYBB	9031.0
NEU1	9029.0
INPPL1	9028.0
SLC2A3	9021.0
BRI3	9017.0
TLR4	9016.0
APAF1	9015.0
GYG1	9013.0
ACTB	9011.0
PRKCD	9008.0
DLG4	9007.0
ALOX5	9001.0
CLTC	9000.0
RETN	8998.0
LILRB4	8977.0
HCK	8976.0
CTSZ	8975.0
CD300C	8972.0
KL	8963.0
PVR	8954.0
MAPK3	8953.0
S100A11	8946.0
ITGB2	8942.0
PRDX6	8937.0
SERPINB10	8933.0
TLR1	8932.0
RAB10	8926.0
MYO10	8918.0
IL1R1	8917.0
SELL	8912.0
CRK	8906.0
CYB5R3	8903.0
NLRP3	8901.0
ARPC1A	8894.0
ITGA2B	8893.0
TGFA	8889.0
MAP2K6	8887.0
F13A1	8876.0
ZDHHC9	8872.0
LILRB3	8871.0
TRIM71	8867.0
CCR1	8865.0
HGF	8863.0
FCGR2A	8845.0
TLR6	8840.0
NUP58	8820.0
MKRN1	8817.0
CEBPD	8816.0
LAT2	8799.0
LY96	8795.0
RHOU	8794.0
RAC1	8793.0
ADAM10	8791.0
LAMP2	8786.0
HEXB	8776.0
ARG1	8759.0
LGALS3	8752.0
C1QC	8750.0
GSN	8749.0
MAP2K3	8748.0
ALPK1	8745.0
APBB1IP	8744.0
RAB7A	8742.0
TNFAIP6	8738.0
AMPD3	8732.0
AP1B1	8730.0
GLB1	8725.0
OLFM4	8724.0
BCL2L1	8700.0
MARK3	8697.0
CSF3R	8687.0
ARPC5	8686.0
FOXO3	8682.0
DNAJC5	8679.0
TIMP1	8677.0
LRG1	8674.0
FTL	8665.0
ALDH3B1	8663.0
RAB5C	8655.0
UBE2D3	8640.0
PYCARD	8638.0
PDXK	8635.0
DNASE1L1	8632.0
SNAP23	8628.0
AP2M1	8627.0
FBXL19	8620.0
TRAF7	8612.0
CDC34	8611.0
MEFV	8605.0
ATP6V0B	8598.0
CAPZA2	8597.0
ATP6V0E1	8596.0
SIAH2	8578.0
TOLLIP	8572.0
GLA	8570.0
IRS2	8569.0
CAPN1	8563.0
ACTG1	8562.0
WAS	8560.0
RNF135	8556.0
UBE2R2	8548.0
ANXA2	8544.0
ATP6V1C1	8539.0
CD68	8533.0
ASAH1	8529.0
TLN1	8525.0
MMP25	8515.0
ALAD	8514.0
RNF130	8510.0
DERA	8500.0
STX3	8492.0
ARRB2	8490.0
RHOG	8487.0
PSMB7	8485.0
FGR	8478.0
HPSE	8476.0
CLEC5A	8473.0
MAP3K3	8471.0
PTEN	8460.0
PLAC8	8452.0
NOD2	8442.0
P4HB	8440.0
P2RX1	8436.0
DNAJC3	8435.0
CEACAM1	8429.0
PLAUR	8424.0
PNP	8419.0
IFNAR1	8413.0
RAB27A	8411.0
TRIM8	8403.0
PSMD4	8402.0
EIF4G3	8400.0
HEBP2	8398.0
ATP11A	8394.0
RNF41	8389.0
DCTN4	8387.0
MAPKAPK3	8382.0
LCP1	8381.0
RILP	8377.0
CLTA	8376.0
CTSS	8372.0
TNFSF13	8370.0
WASF2	8369.0
RNF217	8367.0
RNF144B	8364.0
TMBIM1	8361.0
CPPED1	8357.0
UBAC1	8353.0
C1QB	8337.0
CD44	8333.0
S100P	8331.0
CD99	8326.0
CLEC4E	8324.0
RHOA	8319.0
PELI2	8314.0
KIF3C	8306.0
FUCA2	8304.0
SOS2	8299.0
ACAA1	8292.0
ITGB3	8291.0
TXN	8285.0
FN1	8284.0
HMOX1	8278.0
ARPC3	8277.0
CAB39	8276.0
UBE2J2	8268.0
DNAJC13	8263.0
CLEC4A	8260.0
GMFG	8259.0
MOSPD2	8252.0
PSME3	8251.0
ARL8A	8249.0
KIF5B	8239.0
PPP2CA	8234.0
PAK1	8230.0
TRIM25	8226.0
VAMP3	8222.0
JAK3	8219.0
PRCP	8218.0
ADGRG3	8204.0
C5AR2	8187.0
CFL1	8186.0
PAK2	8185.0
EGF	8179.0
PPP3R1	8175.0
SIGLEC5	8161.0
IQGAP1	8152.0
PTPN12	8151.0
RAB6A	8148.0
LYPLA1	8143.0
MYD88	8136.0
CAPZA1	8135.0
ATG7	8134.0
RAB3A	8133.0
IL6R	8132.0
FCER1G	8131.0
NECTIN2	8124.0
SEC24D	8115.0
CAP1	8111.0
ADAM17	8110.0
JAML	8107.0
PSMB5	8101.0
GAB2	8099.0
STAT3	8098.0
HSPA1A	8071.0
CD33	8069.0
ATP6V1H	8064.0
PLEKHO2	8059.0
LILRB2	8057.0
ANO6	8048.0
TMEM30A	8036.0
ATP6V1E1	8035.0
ATP6AP2	8034.0
EIF4G1	8031.0
VASP	8027.0
AP2S1	8026.0
CAPZB	8015.0
C3AR1	8012.0
MEF2A	8009.0
ORM1	7971.0
GAA	7968.0
COMMD9	7967.0
CHUK	7966.0
PSEN1	7961.0
ICAM5	7936.0
PTK2B	7935.0
COTL1	7933.0
UBE2W	7929.0
NUP214	7921.0
RNF7	7913.0
PGLYRP1	7910.0
SIGLEC7	7897.0
VAV1	7896.0
CMTM6	7891.0
CD53	7884.0
RAF1	7879.0
NEDD4L	7875.0
ACTR2	7870.0
KCMF1	7869.0
TREML1	7868.0
WSB1	7862.0
PECAM1	7855.0
PSMD6	7846.0
SIRPB1	7843.0
ANXA1	7842.0
PSTPIP1	7841.0
NLRX1	7826.0
ACTR3	7818.0
PIK3AP1	7811.0
LYN	7809.0
ICAM3	7808.0
TRAPPC1	7806.0
RAB18	7801.0
RNASEL	7797.0
PGRMC1	7795.0
FSCN1	7794.0
LILRA1	7792.0
PTPRJ	7783.0
OSM	7780.0
UBA3	7767.0
CNPY3	7761.0
PROS1	7758.0
LCN2	7755.0
DBNL	7749.0
GLIPR1	7739.0
DYNC1I2	7735.0
DOCK2	7725.0
GUSB	7723.0
PELI3	7716.0
PPP2CB	7712.0
CANT1	7707.0
PIM1	7704.0
RPS6KA1	7695.0
IFI30	7687.0
NPEPPS	7686.0
CASP9	7685.0
ZNRF1	7675.0
NCKAP1L	7673.0
LY86	7667.0
UBE2H	7663.0
CSF2RB	7661.0
SEC24A	7660.0
RGL1	7647.0
LAMP1	7631.0
MAP3K11	7626.0
PSMD9	7620.0
PTPN2	7615.0
LILRB5	7608.0
UNC13D	7607.0
ACTR10	7605.0
SPTA1	7595.0
EIF4A1	7590.0
LAMTOR3	7574.0
ARSB	7572.0
LAMTOR2	7567.0
EIF4E3	7566.0
POLR2E	7563.0
UBE2L3	7561.0
CRISP3	7552.0
TEC	7549.0
TYROBP	7539.0
CDC42	7537.0
RGL2	7520.0
ELOC	7519.0
ARPC4	7516.0
LRRC41	7515.0
TANK	7502.0
FBXO7	7498.0
MAPK1	7493.0
ROCK1	7489.0
PJA2	7486.0
ELOB	7482.0
CBL	7480.0
UBE2M	7477.0
RNASE3	7471.0
VEGFA	7467.0
NCKAP1	7462.0
SIGLEC11	7456.0
FOLR3	7451.0
CFP	7445.0
MPO	7437.0
HIF1A	7436.0
OSTF1	7426.0
CD1D	7417.0
NAPRT	7412.0
PSMD2	7411.0
FUCA1	7408.0
ARPC2	7390.0
MANBA	7386.0
IL18	7381.0
KLC3	7377.0
EIF4E2	7373.0
PLD3	7364.0
PIAS1	7361.0
IL4R	7358.0
TNFSF12	7349.0
FRS3	7343.0
UBE2F	7341.0
ITGAX	7337.0
SEC23A	7335.0
NCF1	7334.0
SHOC2	7333.0
PSMA1	7329.0
VCL	7328.0
COPB1	7321.0
ELANE	7320.0
DOCK1	7314.0
RNF182	7310.0
UBE2A	7309.0
RAP1A	7305.0
DCTN6	7300.0
LILRB1	7287.0
GDI2	7282.0
EIF4A3	7273.0
AP2A2	7257.0
PSMD1	7241.0
TUBB4B	7240.0
TNFSF13B	7238.0
LYZ	7213.0
BTK	7206.0
FLT3	7196.0
CLEC4G	7195.0
TCIRG1	7188.0
CD300LB	7186.0
LAIR1	7184.0
PLD2	7180.0
PSMB3	7171.0
SIGLEC10	7158.0
IL1RAP	7150.0
IGF2R	7149.0
PSAP	7145.0
MCL1	7133.0
MAVS	7124.0
IL27	7120.0
PILRA	7112.0
GALNS	7102.0
PRKCB	7097.0
PSMA7	7096.0
RAB14	7095.0
UBA1	7089.0
TYK2	7087.0
NBEAL2	7086.0
TRIM10	7084.0
ABI1	7082.0
PPP1CB	7064.0
SURF4	7058.0
MVP	7053.0
DNM3	7045.0
BRK1	7032.0
HSPA5	7029.0
PSMC1	7021.0
SEC61B	7013.0
TREM1	7009.0
PPP3CB	7005.0
UBE2B	7003.0
ACTR1A	7002.0
TSPAN14	6971.0
ATP8B4	6970.0
STAT5A	6965.0
TAB2	6964.0
DUSP1	6950.0
PAFAH1B2	6942.0
DYNC1LI1	6941.0
SPRED2	6936.0
DDOST	6931.0
TNFRSF12A	6928.0
STAT5B	6925.0
ITGB5	6923.0
CYBA	6922.0
TRIP12	6921.0
METTL7A	6920.0
EIF4G2	6918.0
ERP44	6905.0
CSTB	6904.0
PRKG1	6901.0
MMP1	6891.0
SUMO1	6889.0
VCP	6886.0
UBE2K	6884.0
MAN2B1	6878.0
RAPGEF2	6867.0
MAP2K4	6866.0
CXCR1	6864.0
CEACAM3	6838.0
RNASE6	6837.0
AP2A1	6832.0
CUL3	6821.0
PITPNA	6820.0
PSMB6	6813.0
WASF3	6808.0
NFKBIA	6807.0
JUNB	6806.0
RNF123	6802.0
MAP2K2	6794.0
PPP2R5B	6774.0
RNF19B	6764.0
PRTN3	6762.0
UBE2E1	6759.0
IL19	6757.0
CD300E	6742.0
CLEC6A	6730.0
PELI1	6715.0
PTPN9	6712.0
AP1M1	6711.0
ICAM1	6705.0
STOM	6704.0
H3C15	6699.5
FBXO11	6698.0
MYO5A	6693.0
RAB5B	6690.0
CD300LD	6686.0
MYH9	6685.0
YPEL5	6684.0
BPI	6666.0
IFNAR2	6665.0
PSMF1	6659.0
CD300LF	6658.0
CARD9	6648.0
CD58	6647.0
CNN2	6645.0
VWF	6641.0
UBB	6639.0
BTNL8	6638.0
PSMC6	6635.0
C1QA	6626.0
DDX3X	6614.0
IQGAP2	6599.0
MUC1	6573.0
POLR1D	6566.0
FBXW2	6560.0
PSMD12	6556.0
CCT8	6552.0
HSPA6	6514.0
AOC1	6509.0
LPO	6502.0
IRF5	6499.0
SAR1B	6479.0
HSPA1B	6470.0
AREL1	6465.0
AHCYL1	6456.0
TREML2	6454.0
SEC61A1	6449.0
CGAS	6444.0
IRF2	6427.0
MYO9B	6424.0
TREML4	6422.0
CTNNB1	6408.0
ARMC8	6398.0
SAMHD1	6397.0
SNAP29	6390.0
BATF	6386.0
YWHAB	6385.0
KBTBD7	6376.0
RCHY1	6374.0
CTSH	6360.0
CALR	6340.0
TICAM2	6335.0
PPP1CC	6330.0
SRP14	6320.0
TICAM1	6307.0
LTF	6306.0
LRRFIP1	6302.0
GPI	6284.0
UBE3C	6282.0
NFKB1	6277.0
PANX1	6267.0
ELMO1	6258.0
ARHGAP9	6256.0
PSMD11	6231.0
ASB7	6221.0
PPP3CA	6217.0
GGH	6205.0
NEDD4	6201.0
FBXW11	6196.0
C6orf120	6192.0
TCN1	6182.0
SH3KBP1	6173.0
DEGS1	6169.0
ANAPC11	6161.0
MAP3K8	6160.0
DTX4	6156.0
RGL3	6150.0
PTPN18	6149.0
PDPK1	6136.0
IRAK1	6131.0
EP300	6129.0
VPS35L	6118.0
ITGAV	6106.0
PTPN6	6096.0
NDUFC2	6093.0
DNM2	6089.0
FNTB	6081.0
ATP11B	6064.0
DEFA1	6061.0
DEFA4	6057.0
PIK3CD	6046.0
TNFRSF1B	6045.0
PPBP	6042.0
TAX1BP1	6031.0
FABP5	6021.0
CHIT1	6012.0
ORAI2	6010.0
DCTN3	5994.0
AREG	5977.0
PSMA6	5970.0
PSMD7	5963.0
DYNLL1	5952.0
PSMD13	5948.0
RNASET2	5922.0
CASP4	5919.0
PDAP1	5908.0
PPP2R5A	5897.0
STAT6	5884.0
IFITM2	5880.0
ATP6V1F	5878.0
SEC22B	5873.0
CPNE3	5872.0
IST1	5862.0
CXCR2	5861.0
CD59	5859.0
PDGFRA	5858.0
SERPINB6	5854.0
CD46	5851.0
BCL10	5849.0
PGM1	5843.0
ITPR2	5842.0
GRIN2D	5841.0
CXCL1	5824.0
RANBP9	5813.0
PTX3	5797.0
MGRN1	5794.0
UBE2Q1	5780.0
PSMD8	5757.0
RNF111	5749.0
SEC13	5748.0
BIN2	5745.0
ATP6V1E2	5730.0
PTPN1	5722.0
WIPF2	5713.0
ATF1	5706.0
TAB1	5681.0
GAB1	5679.0
PPM1B	5655.0
FADD	5641.0
TIRAP	5640.0
UBE2V1	5637.0
ADAM8	5634.0
YWHAZ	5624.0
CLEC7A	5608.0
A1BG	5559.0
FAF2	5554.0
TNIP2	5552.0
STBD1	5544.0
FBXL13	5534.0
CANX	5528.0
MSN	5524.0
KLC1	5523.0
KIF23	5510.0
AZU1	5507.0
TNFRSF8	5504.0
FBXL4	5496.0
DAPP1	5474.0
RLIM	5462.0
FOS	5460.0
NPC2	5458.0
CXCL2	5412.0
BRAP	5387.0
DEFA3	5385.0
XRCC5	5384.0
IKBKG	5377.0
NRAS	5363.0
RAB24	5354.0
PSMA2	5339.0
IL13RA1	5336.0
PTPN11	5314.0
TARM1	5307.0
DGAT1	5306.0
POLR2L	5305.0
SLPI	5298.0
PDGFA	5293.0
TKFC	5285.0
PCBP2	5283.0
PAG1	5268.0
TRIM34	5261.0
PDE6D	5250.0
PRKCSH	5220.0
CSK	5219.0
VAMP8	5218.0
PTPRN2	5183.0
RAE1	5164.0
RAC2	5163.0
ACLY	5159.0
TGFB1	5153.0
MAP3K1	5121.0
CTSG	5115.0
KLHL5	5105.0
UBE2C	5101.0
KIF20A	5096.0
SIGLEC14	5087.0
DCTN1	5078.0
CTSK	5059.0
MAPKAP1	5057.0
KLHL21	5054.0
TIFA	5046.0
HBEGF	5013.0
PIK3R2	5010.0
PLCG2	5006.0
UBE2E3	5005.0
KPNA4	4957.0
CEACAM8	4956.0
UBE2G1	4921.0
ECSIT	4918.0
CISH	4915.0
HVCN1	4912.0
PLAU	4903.0
FTH1	4902.0
KEAP1	4898.0
HERC4	4895.0
VAV3	4894.0
ASB8	4884.0
HECW2	4860.0
CNTF	4845.0
FBXL20	4844.0
LRSAM1	4831.0
CRCP	4826.0
EIF4E	4813.0
IL1B	4807.0
STING1	4791.0
CAMP	4785.0
ABCA13	4768.0
PTGS2	4753.0
UBE2S	4746.0
C4BPA	4735.0
SMARCA4	4733.0
IKBKE	4715.0
SEC61G	4708.0
BIRC2	4692.0
GRAP2	4690.0
FBXO30	4683.0
LIMK1	4679.0
UBE2D2	4657.0
EEA1	4641.0
HAVCR2	4630.0
PIK3CA	4629.0
PSMD3	4618.0
POLR2F	4604.0
RAP2C	4599.0
PPP2R1A	4589.0
LONRF1	4539.0
KRT1	4537.0
CLEC12A	4535.0
NUP50	4521.0
CDKN1A	4511.0
CEACAM6	4509.0
FBXL15	4499.0
C4A	4466.0
PTK2	4462.0
DYNLT1	4450.0
UBC	4439.0
ELMO2	4397.0
SOD2	4390.0
RNF138	4382.0
KCTD6	4371.0
RNF14	4363.0
DUSP6	4357.0
SEM1	4348.0
ATOX1	4338.0
MAPK10	4325.0
SP100	4314.0
FCGR3B	4313.0
B4GALT1	4292.0
SKP1	4287.0
DYNC1LI2	4273.0
CTF1	4260.0
CTSL	4231.0
CASP1	4224.0
RIPK3	4217.0
DYNC1I1	4187.0
SHC2	4183.0
UNC93B1	4170.0
KSR1	4167.0
SHC1	4161.0
GHDC	4158.0
CD101	4146.0
PDIA3	4128.0
CPN2	4118.0
UBR2	4099.0
PSMB2	4084.0
SQSTM1	4081.0
GOLGA7	4055.0
MAPKAPK2	4054.0
IL6ST	4025.0
FBXL8	4021.0
SIPA1	4012.0
CDC20	3998.0
IL18R1	3994.0
AP1G1	3987.0
SHC3	3974.0
CSNK2B	3969.0
NDN	3968.0
CRKL	3966.0
C5	3954.0
SOCS1	3947.0
RNF6	3943.0
STIM1	3938.0
RBX1	3934.0
ATP6V1G1	3931.0
HNRNPF	3929.0
C2	3925.0
C4B	3922.0
FGF2	3920.0
MAPK13	3865.0
EBI3	3833.0
MAPK11	3826.0
SIGLEC12	3770.0
NRG1	3750.0
KIF3B	3740.0
BIRC5	3738.0
SLC15A4	3724.0
JUN	3722.0
RELB	3721.0
WDR83	3718.0
KRAS	3702.0
VHL	3674.0
TCP1	3660.0
AKT1	3614.0
SEC24B	3608.0
DNM1	3587.0
STK11IP	3586.0
KIF4A	3585.0
REL	3527.0
ARSA	3486.0
P2RX7	3475.0
FBXO17	3474.0
IL27RA	3441.0
UBA6	3438.0
PSMD5	3426.0
DDX41	3424.0
CREBBP	3423.0
HNRNPA2B1	3380.0
PSMB1	3374.0
ASB13	3324.0
ASB1	3319.0
MYO1C	3310.0
FBXL18	3309.0
TNFSF4	3271.0
TBK1	3229.0
SLCO4C1	3212.0
RAP1B	3206.0
SOCS5	3184.0
IL1RL1	3175.0
TAB3	3160.0
RAB4B	3137.0
EGR1	3124.0
MRC1	3109.0
NUP98	3101.0
RPS6KA2	3087.0
NUP37	3074.0
NF1	3036.0
PI3	3023.0
BLMH	3017.0
LGALS9	3016.0
TAPBP	3010.0
RNF114	2998.0
UBE3A	2978.0
RPS6KA3	2973.0
PSPN	2969.0
CDC26	2923.0
ANAPC13	2921.0
UBE2V2	2902.0
POMC	2855.0
RACGAP1	2848.0
KBTBD6	2724.0
RALA	2710.0
SLC44A2	2700.0
JAK2	2691.0
EPGN	2662.0
ARAF	2644.0
IRF8	2617.0
MAGT1	2613.0
PSMD14	2611.0
PSMC2	2598.0
IL15RA	2585.0
ANGPT1	2562.0
CUL2	2526.0
PSMB4	2523.0
OLR1	2486.0
COL1A2	2469.0
CD177	2457.0
TRIM38	2449.0
TNFSF14	2443.0
KPNB1	2430.0
TRIM21	2428.0
TRIM41	2424.0
PPP2R5D	2421.0
MAP3K7	2395.0
SPSB1	2374.0
FBXO40	2368.0
MS4A3	2361.0
MICB	2355.0
CTSC	2326.0
MLEC	2322.0
MYC	2304.0
BTBD1	2263.0
EPPIN	2251.0
PTPRC	2240.0
RBCK1	2214.0
CST3	2206.0
MADCAM1	2165.0
OPRM1	2161.0
UBE2O	2123.0
RASA1	2106.0
TRIM4	2088.0
ATF2	2085.0
BTN1A1	2068.0
HSP90B1	2059.0
SLC2A5	2044.0
NANOG	2038.0
SVIP	2035.0
ICAM4	2006.0
ARRB1	1998.0
CFD	1984.0
PSMC3	1976.0
UBE4A	1970.0
GSDMD	1955.0
UBE2N	1936.0
CAMK2G	1921.0
UBE3B	1890.0
EREG	1888.0
SCAMP1	1868.0
HGSNAT	1867.0
NME2	1850.0
GBP6	1836.0
AP1M2	1832.0
UBE2E2	1779.0
FLNB	1747.0
TRIM9	1746.0
IRS1	1741.0
CXCL8	1729.0
MMP9	1690.0
PPL	1679.0
MAP2K7	1654.0
FCGR2B	1649.0
PIK3C3	1619.0
ASB9	1587.0
PSMD10	1559.0
SUGT1	1544.0
POU2F1	1537.0
NPDC1	1409.0
ATG5	1398.0
NOS1	1365.0
KLHL9	1353.0
HSP90AA1	1326.0
ASB3	1325.0
ITCH	1318.0
BRAF	1308.0
KPNA1	1296.0
AGER	1294.0
VRK3	1281.0
NHLRC3	1276.0
BOLA2	1257.0
HECTD3	1201.0
UBA52	1121.0
SEC31A	1099.0
ELK1	1040.0
RIPK2	1025.0
DHX9	1019.0
HLA-C	1018.0
HERC3	1012.0
FBXL3	1005.0
APEH	997.0
KPNA3	923.0
MME	916.0
NFASC	866.0
CUL5	834.0
IL18RAP	823.0
KIF11	787.0
NUP62	769.0
KIF2C	726.0
KLHL13	702.0
ATP7A	694.0
ZBTB16	689.0
FGL2	675.0
HLA-B	649.0
ZNRF2	633.0
STX4	606.0
RAB44	573.0
WIPF1	569.0
TNFRSF9	566.0
PYGB	492.0
FLNA	483.0
TRIM6	456.0
TMEM179B	449.0
IL33	445.0
AKT2	433.0
ADGRE3	408.0
CSF1R	394.0
TXNDC5	393.0
MLST8	376.0
NKIRAS1	375.0
IGHV1-2	360.0
CENPE	332.0
NCKIPSD	328.0
EEF2	306.0
WASL	299.0
FBXW5	265.0
IGHV2-5	230.0
ABL1	226.0
IL17RC	193.0
GSTP1	135.0
IFI16	105.0
IGHV3-53	103.0
RASAL2	79.0
CD86	-14.0
FRK	-24.0
ABHD17B	-35.0
PTPN3	-85.0
ITGB1	-94.0
KCNAB2	-101.0
PRDX4	-144.0
NFKBIB	-152.0
EDA	-156.0
MRC2	-165.0
BAIAP2	-215.0
IFI27	-223.0
TRAF6	-229.0
PPP2R1B	-241.0
HMGB1	-252.0
MEF2C	-293.0
IFITM3	-359.0
IGHV3-7	-441.0
ERBB3	-472.0
GHR	-479.0
PIGR	-487.0
ARL2	-565.0
CD180	-600.0
PSMA4	-616.0
IGHV1-46	-618.0
TLR7	-625.0
CASP3	-632.0
CHI3L1	-650.0
CDC27	-651.0
FBXO41	-657.0
IGHV3-48	-668.0
PPP2R5E	-680.0
PIANP	-751.0
ATG12	-770.0
RAP2B	-771.0
IGKV3-11	-781.0
ICMT	-786.0
RANBP2	-820.0
DIAPH1	-854.0
PSMC5	-863.0
IGKV1-39	-989.0
RPLP0	-1000.0
IGLV7-46	-1016.0
TNFSF15	-1028.0
STUB1	-1032.0
RASAL1	-1060.0
KIF2A	-1069.0
MAPK12	-1074.0
UBOX5	-1092.0
RBBP6	-1125.0
ULBP3	-1147.0
LCP2	-1156.0
NFKB2	-1165.0
IGKV1-5	-1184.0
PTPN23	-1186.0
TREX1	-1198.0
PTPN22	-1208.0
TNFRSF13B	-1257.0
TRIM3	-1268.0
FBXO15	-1269.0
IGLV2-8	-1294.0
IGKV5-2	-1298.0
IGHV3-23	-1317.0
FBXL12	-1321.0
MAPK7	-1337.0
COMMD3	-1363.0
CREB1	-1378.0
GAN	-1414.0
IGHV3-13	-1443.0
CRLF1	-1508.0
IGLV2-18	-1524.0
IGKV1-16	-1528.0
IGLV4-69	-1559.0
IGKV1D-39	-1574.0
OSMR	-1577.0
DUSP10	-1650.0
AIM2	-1718.0
POLR2K	-1783.0
RELA	-1803.0
DSP	-1812.0
IGHV1-69	-1822.0
TXLNA	-1846.0
NRG4	-1875.0
IGLV10-54	-1884.0
LRRC7	-1966.0
ILF2	-1979.0
EDA2R	-1997.0
IGLV1-36	-2030.0
ABHD17C	-2037.0
IGKV2-30	-2045.0
VTN	-2046.0
NOS3	-2059.0
CSF1	-2061.0
CD200	-2065.0
CALM1	-2081.0
UBR4	-2086.0
IGLV7-43	-2089.0
IGLV3-19	-2111.0
CD300A	-2133.0
IGHV3-11	-2134.0
ASB14	-2170.0
IGHM	-2190.0
MUCL1	-2211.0
ATP6V1C2	-2219.0
FZR1	-2233.0
AP1S2	-2261.0
ARIH1	-2279.0
PGLYRP2	-2281.0
IGKV3-15	-2297.0
FBXO6	-2300.0
UNKL	-2338.0
PTPN14	-2386.0
C1S	-2420.0
IGKV1-33	-2424.0
C4BPB	-2452.0
HLA-G	-2457.0
POLR3K	-2467.0
CASP2	-2471.0
IGHV3-30	-2484.0
HECTD1	-2490.0
IGKV4-1	-2532.0
SOCS2	-2538.0
ORM2	-2564.0
SEC24C	-2569.0
ADGRE5	-2571.0
HLA-A	-2573.0
SMURF1	-2591.0
CD1A	-2596.0
LTN1	-2597.0
ENAH	-2707.0
AP2B1	-2709.0
KIF18A	-2742.0
ASB6	-2763.0
APRT	-2766.0
IGKV1-17	-2871.0
IGLV2-23	-2878.0
IGLV6-57	-2885.0
IGHV4-59	-2892.0
IGLV2-11	-2905.0
RAPGEF3	-2911.0
POLR2H	-2942.0
TLR10	-2961.0
MUC6	-2977.0
IGHV3-33	-2988.0
PHB	-2995.0
SIAH1	-3000.0
IGHV4-34	-3016.0
CCL3	-3027.0
CTSV	-3036.0
NUP85	-3049.0
PSMB8	-3076.0
IGKV3-20	-3085.0
AGL	-3136.0
IGHV2-70	-3138.0
PIN1	-3188.0
MUC4	-3191.0
DUSP7	-3211.0
KIF15	-3249.0
IGLV1-44	-3258.0
LAMA5	-3263.0
PFKL	-3277.0
FGFR4	-3293.0
PDCD1LG2	-3326.0
CUL7	-3334.0
KSR2	-3361.0
HRAS	-3382.0
CPNE1	-3397.0
TNFSF11	-3409.0
FRS2	-3433.0
ALDOC	-3438.0
ADAR	-3442.0
CASP10	-3446.0
HTN1	-3453.0
IGHG3	-3481.0
CFB	-3518.0
SPTBN5	-3531.0
AIP	-3566.0
AAMP	-3636.0
TRIM11	-3671.0
FBXO22	-3709.0
PTPN20	-3783.0
DAB2IP	-3826.0
SLC27A2	-3831.0
CD19	-3843.0
MIF	-3863.0
PAQR3	-3864.0
HLA-H	-3889.0
IGKV3D-20	-3894.0
STK10	-3898.0
PA2G4	-3916.0
DYNLL2	-3980.0
MYLIP	-3991.0
SPSB2	-4034.0
INPP5D	-4038.0
STX1A	-4052.0
VAV2	-4055.0
PIK3R4	-4062.0
DCTN5	-4086.0
MUC16	-4104.0
RASGRF1	-4123.0
IGLV3-1	-4159.0
PAK3	-4184.0
KBTBD8	-4224.0
FCER2	-4230.0
FGF7	-4247.0
TNFRSF17	-4308.0
RASA2	-4320.0
CR2	-4340.0
COLEC12	-4367.0
IGHD	-4407.0
HLA-E	-4415.0
IGKC	-4428.0
XRCC6	-4471.0
TNFRSF13C	-4479.0
RBSN	-4542.0
TRIM2	-4562.0
IGHV4-39	-4582.0
DPP7	-4586.0
MUC5B	-4613.0
PTPRA	-4626.0
SYNGR1	-4629.0
AGA	-4632.0
LGMN	-4644.0
RCE1	-4674.0
LEAP2	-4703.0
BCL2	-4704.0
UBR1	-4734.0
IGLV3-21	-4735.0
CNKSR2	-4781.0
OPRD1	-4782.0
IGLV1-40	-4788.0
CD22	-4791.0
LNX1	-4796.0
HLA-DQA2	-4806.0
EPX	-4838.0
SOD1	-4862.0
BTRC	-4924.0
KIF26A	-4925.0
IGLV3-25	-4933.0
IGLV1-51	-4956.0
HLA-DRB5	-4971.0
CD40	-4995.0
ANAPC10	-5000.0
IL15	-5043.0
BTNL9	-5071.0
FBXO27	-5074.0
EEF1A1	-5087.0
IGHE	-5123.0
SPTBN2	-5129.0
OTUD5	-5132.0
SH3RF1	-5151.0
CD79A	-5158.0
HCST	-5160.0
HLA-DOB	-5177.0
ANAPC7	-5181.0
POLR3F	-5191.0
BTBD6	-5202.0
MICA	-5227.0
DHX36	-5245.0
IGLC7	-5281.0
PSMA3	-5285.0
CLEC10A	-5299.0
ERAP2	-5338.0
FGFR1	-5352.0
JUP	-5353.0
MASP2	-5358.0
NFKBIE	-5377.0
IKBKB	-5386.0
BLK	-5388.0
DTX3L	-5393.0
POLR3G	-5401.0
CD4	-5406.0
IL17RE	-5421.0
NEFL	-5425.0
IGLV8-61	-5427.0
IGKV1-12	-5446.0
S100B	-5457.0
IGLC3	-5477.0
IGLC2	-5510.0
AP1S3	-5522.0
CFH	-5562.0
NUP42	-5564.0
TRAF3	-5576.0
ASB4	-5604.0
BTLA	-5625.0
IGKV2D-28	-5634.0
MX2	-5647.0
IFI35	-5670.0
SOS1	-5700.0
RASGEF1A	-5704.0
DLG2	-5717.0
FNTA	-5724.0
PSMB10	-5735.0
MTAP	-5790.0
IGKV2-28	-5808.0
OSBPL1A	-5816.0
TRIB3	-5843.0
HACE1	-5851.0
IGLV5-45	-5869.0
IGLV3-27	-5874.0
MUC20	-5962.0
KIR2DL4	-5995.0
TLR9	-5999.0
IGLV1-47	-6018.0
PSMA5	-6053.0
SEH1L	-6069.0
CDC16	-6071.0
PSME4	-6087.0
TNFSF9	-6091.0
FBXL14	-6145.0
RNF34	-6150.0
IGLC1	-6157.0
MRAS	-6172.0
IGHG1	-6201.0
IFITM1	-6264.0
KLHL11	-6286.0
DUSP4	-6287.0
PDZD11	-6288.0
PDE12	-6298.0
RNF220	-6303.0
NUP153	-6321.0
NLRP1	-6332.0
CD70	-6370.0
HLA-DQB1	-6416.0
FBXO10	-6427.0
TNFRSF14	-6445.0
IL17RB	-6506.0
NF2	-6540.0
RAB9B	-6552.0
CAND1	-6554.0
FBXW7	-6600.0
FGF23	-6622.0
IL17C	-6641.0
ANAPC4	-6644.0
FBXL16	-6648.0
DUSP16	-6655.0
TNFRSF4	-6657.0
ASB16	-6665.0
TRIM36	-6670.0
UFL1	-6680.0
EDAR	-6693.0
TRIM14	-6730.0
SIGLEC8	-6747.0
PPIA	-6766.0
PDCD1	-6792.0
PEA15	-6825.0
SPRED3	-6835.0
CD80	-6841.0
ICOSLG	-6859.0
HSP90AB1	-6863.0
ITLN1	-6873.0
KPNA2	-6910.0
IGHG4	-6911.0
B2M	-6920.0
PTGES2	-6926.0
DSC1	-6927.0
RPS27A	-6938.0
TUBB	-6956.0
CCND1	-6970.0
TRIM5	-6975.0
MT2A	-6990.0
TPR	-7028.0
SIKE1	-7060.0
MAPK9	-7068.0
TNFSF8	-7086.0
CNKSR1	-7089.0
ORAI1	-7096.0
GBP2	-7142.0
IL2RA	-7161.0
POM121C	-7188.0
BLNK	-7227.0
IGHG2	-7250.0
TRAV8-4	-7261.0
RNF25	-7289.0
TNF	-7308.0
POLR3A	-7324.0
HRNR	-7349.0
POLR3B	-7356.0
IGLV3-12	-7358.0
FBXW9	-7360.0
ERAP1	-7370.0
BST2	-7385.0
ANAPC2	-7407.0
POLR3C	-7421.0
LPCAT1	-7428.0
PLPP5	-7430.0
CD79B	-7443.0
PPP5C	-7462.0
ZEB1	-7466.0
POLR3GL	-7481.0
TRAT1	-7535.0
UBA7	-7558.0
CD274	-7563.0
PSMA8	-7606.0
PTPRB	-7607.0
ITPR1	-7629.0
IL31RA	-7636.0
LRR1	-7643.0
DYNC1H1	-7685.0
TRIM45	-7697.0
TNFRSF18	-7726.0
NUP133	-7762.0
SPTBN1	-7764.0
IL12A	-7823.0
RET	-7856.0
CCR6	-7862.0
MRE11	-7923.0
TRIM46	-7951.0
HUWE1	-7977.0
PRKCE	-8001.0
TNFRSF11A	-8033.0
UBE2G2	-8035.0
HLA-DRB1	-8075.0
S100A1	-8108.0
CD226	-8138.0
CXCL10	-8160.0
CD8B	-8188.0
SKP2	-8279.0
POM121	-8299.0
UBA5	-8300.0
FBXO2	-8324.0
DLG1	-8336.0
IGLV2-14	-8345.0
FBXW12	-8358.0
KLHL42	-8367.0
KLC4	-8376.0
AAAS	-8389.0
BTN2A1	-8390.0
CDK13	-8392.0
KIR2DS4	-8405.0
LTB	-8406.0
PRKG2	-8477.0
NUP54	-8479.0
TRIM37	-8494.0
IRF1	-8510.0
IRF3	-8517.0
RASGRP2	-8529.0
IL7	-8554.0
RORC	-8573.0
PDGFB	-8577.0
FGF22	-8607.0
KIFAP3	-8619.0
LAIR2	-8627.0
SPRED1	-8639.0
IRF7	-8657.0
SH2B1	-8670.0
GFRA2	-8689.0
PML	-8693.0
TRIM56	-8736.0
FGF9	-8761.0
IFNLR1	-8808.0
SRC	-8820.0
CCT2	-8825.0
CCR5	-8861.0
KIF5C	-8865.0
KIF5A	-8869.0
CLEC2B	-8920.0
IL20RB	-8921.0
IRF4	-8967.0
CD34	-8972.0
TPP2	-8977.0
GBP3	-8979.0
PPIE	-9002.0
HECTD2	-9020.0
KLC2	-9059.0
CRACR2A	-9069.0
TRIM26	-9081.0
EIF2AK2	-9116.0
PSMC4	-9127.0
TMEM63A	-9137.0
SYNGAP1	-9140.0
CD209	-9143.0
NFATC1	-9147.0
KIR2DL3	-9153.0
CEP290	-9182.0
DET1	-9199.0
FBXL22	-9210.0
S1PR1	-9211.0
BRWD1	-9221.0
CD81	-9227.0
CCNF	-9262.0
SIGLEC6	-9283.0
HERC1	-9297.0
CYLD	-9359.0
DUSP2	-9373.0
HLA-DQB2	-9401.0
RASGRP3	-9414.0
CD200R1	-9422.0
MAPK8	-9428.0
ICOS	-9434.0
THOP1	-9447.0
FOXO1	-9465.0
CIITA	-9470.0
PIK3R1	-9505.0
HLA-DMB	-9507.0
ATP6V1G2	-9515.0
NUP43	-9517.0
IRF6	-9518.0
TRBV7-9	-9539.0
IRAK2	-9548.0
OAS1	-9574.0
KLRC2	-9578.0
ENPP4	-9583.0
TRIM69	-9591.0
TXNIP	-9600.0
PJA1	-9611.0
LNPEP	-9618.0
FBXO44	-9627.0
C1R	-9669.0
RICTOR	-9670.0
GBP1	-9672.0
TRAV29DV5	-9673.0
TRIM35	-9697.0
LMO7	-9709.0
IL16	-9726.0
TRPC1	-9736.0
IL11RA	-9753.0
MTOR	-9767.0
RNF115	-9777.0
HSPA9	-9780.0
CD27	-9812.0
RAPGEF1	-9826.0
LTA	-9851.0
HLA-DMA	-9886.0
FLT3LG	-9894.0
TRAV19	-9915.0
IMPDH2	-9916.0
PTPN13	-9962.0
PSME1	-9991.0
ORMDL3	-9997.0
FBXW8	-10013.0
SNRPA1	-10023.0
ATAD3B	-10079.0
WWP1	-10106.0
IL32	-10122.0
TRIM17	-10141.0
RASGRF2	-10175.0
RNF19A	-10197.0
CD28	-10202.0
PRKDC	-10219.0
NUP155	-10233.0
IFNG	-10277.0
LAG3	-10294.0
ITPR3	-10308.0
POLR3H	-10310.0
NLRC5	-10323.0
PSME2	-10336.0
SMURF2	-10340.0
CTLA4	-10363.0
CYFIP2	-10367.0
CD40LG	-10384.0
IL4	-10399.0
PRLR	-10410.0
NUP107	-10421.0
TRBV12-3	-10436.0
TRIM39	-10438.0
CD8A	-10476.0
ACTR1B	-10514.0
IL23A	-10538.0
RNF216	-10540.0
RNF126	-10545.0
IL7R	-10546.0
CRTAM	-10549.0
NUP160	-10557.0
IL18BP	-10561.0
TNFRSF25	-10588.0
IL10RA	-10594.0
TMC6	-10606.0
FBXO32	-10607.0
NUP35	-10611.0
STAT2	-10637.0
IP6K2	-10651.0
HERC2	-10658.0
TRIM62	-10661.0
KLHL25	-10671.0
ABHD17A	-10672.0
ALOX15	-10676.0
MUC12	-10704.0
NUP210	-10726.0
ABCE1	-10729.0
SIGIRR	-10752.0
DSN1	-10773.0
UBE3D	-10777.0
TAP1	-10787.0
FBXO21	-10790.0
SEC61A2	-10798.0
OASL	-10836.0
KLRC1	-10837.0
ITGAL	-10847.0
TRIM22	-10849.0
KIR2DL1	-10859.0
PTPN7	-10868.0
TP53	-10893.0
POLR1C	-10899.0
UBE2Z	-10912.0
ABI2	-10915.0
MALT1	-10920.0
HSPA8	-10922.0
EDARADD	-10943.0
TNFAIP3	-10950.0
JAK1	-10955.0
ANAPC5	-10967.0
CCL5	-10985.0
KIT	-11004.0
IL24	-11009.0
DZIP3	-11017.0
NCR3	-11035.0
ITGA4	-11043.0
GBP5	-11062.0
THEM4	-11069.0
MIB2	-11073.0
RIPK1	-11074.0
GLMN	-11075.0
MS4A2	-11106.0
PLCG1	-11120.0
BIRC3	-11125.0
HLA-F	-11138.0
CLCF1	-11150.0
IRF9	-11154.0
EIF4A2	-11157.0
RNF125	-11190.0
SERPING1	-11197.0
UBE2D4	-11203.0
RASA4	-11206.0
IL5RA	-11211.0
ITK	-11223.0
HNRNPDL	-11232.0
KLRG1	-11238.0
PPP2R5C	-11265.0
PEBP1	-11270.0
IFIT5	-11287.0
UBE2L6	-11293.0
CD3E	-11302.0
CDC23	-11304.0
NUP205	-11321.0
PDE3B	-11322.0
PSMB9	-11324.0
PILRB	-11325.0
CUL1	-11330.0
IFIH1	-11332.0
CASP8	-11336.0
CTSO	-11366.0
POLR3E	-11383.0
KIR3DL1	-11385.0
NUP88	-11397.0
CD3D	-11401.0
KLHL22	-11407.0
CD74	-11419.0
KIR3DL2	-11420.0
SPTAN1	-11426.0
GNLY	-11428.0
RAG1	-11432.0
NCK1	-11454.0
RNF4	-11467.0
FRMPD3	-11469.0
TRAC	-11482.0
KLHL20	-11483.0
TRIM32	-11493.0
CDH1	-11500.0
TLR3	-11525.0
CD3G	-11526.0
PDGFRB	-11545.0
KCTD7	-11546.0
CTSF	-11553.0
UBE2Q2	-11554.0
ATP6V0E2	-11555.0
RPS6KA5	-11594.0
ISG20	-11609.0
TRAIP	-11615.0
NUP93	-11620.0
NUP188	-11624.0
KLHL3	-11635.0
DUSP8	-11639.0
C8G	-11641.0
FYN	-11675.0
TXK	-11676.0
LAT	-11694.0
NIT2	-11695.0
MAP3K14	-11702.0
NCAM1	-11706.0
STAT1	-11727.0
BTN2A2	-11730.0
SMAD3	-11745.0
TRAF2	-11746.0
FBXW4	-11757.0
POLR3D	-11777.0
VAMP2	-11779.0
FGFR2	-11785.0
RAB37	-11793.0
TAP2	-11807.0
CLEC4C	-11809.0
HLA-DOA	-11812.0
CAMK2D	-11816.0
HMOX2	-11819.0
RASA3	-11820.0
PDCD4	-11822.0
DHX58	-11824.0
CD160	-11835.0
LCK	-11838.0
GZMM	-11840.0
ATP8A1	-11842.0
FBXO4	-11843.0
GBP4	-11848.0
AKT3	-11849.0
TBC1D10C	-11861.0
IFI6	-11882.0
KPNA5	-11893.0
RNF213	-11905.0
DLG3	-11922.0
NCR3LG1	-11944.0
BTN3A2	-11945.0
ZAP70	-11949.0
DDX58	-11950.0
FBXO31	-11953.0
PRKACB	-11959.0
ANAPC1	-11962.0
KIF3A	-11972.0
RASGRP1	-11974.0
CCL4	-11976.0
ASB2	-11978.0
RORA	-11979.0
PRR5	-11985.0
TRIM68	-11989.0
HLA-DQA1	-11992.0
IL12RB2	-11994.0
FCGR3A	-12005.0
TRBC1	-12006.0
HLA-DRA	-12009.0
RASAL3	-12014.0
PIK3R3	-12015.0
ICAM2	-12026.0
ISG15	-12032.0
IFIT3	-12037.0
FCER1A	-12046.0
IL2RG	-12050.0
IL3RA	-12057.0
KLRD1	-12062.0
XAF1	-12073.0
ARIH2	-12090.0
LILRA4	-12092.0
CD96	-12097.0
IFIT2	-12108.0
CD47	-12114.0
IL12RB1	-12115.0
PLA2G6	-12122.0
PRKCQ	-12127.0
SLAMF7	-12130.0
OAS2	-12131.0
SARM1	-12134.0
MX1	-12138.0
RALGDS	-12140.0
YES1	-12142.0
MEX3C	-12144.0
CD1C	-12147.0
CARD11	-12160.0
SH2D1A	-12167.0
NDC1	-12173.0
NFATC3	-12177.0
IL9R	-12179.0
SIGLEC1	-12182.0
ITGB7	-12187.0
OAS3	-12188.0
GATA3	-12191.0
SLAMF6	-12193.0
NLRC3	-12203.0
HERC6	-12205.0
EVL	-12207.0
ATP6V0A2	-12211.0
USP18	-12214.0
PTPN4	-12220.0
HERC5	-12225.0
DUSP5	-12227.0
RSAD2	-12233.0
HLA-DPB1	-12248.0
IL21R	-12256.0
C3	-12262.0
NOD1	-12263.0
KLRB1	-12265.0
CLEC2D	-12275.0
NFATC2	-12294.0
CBLB	-12303.0
KLRK1	-12309.0
HLA-DPA1	-12316.0
IFIT1	-12318.0
ERBB2	-12320.0
ZBP1	-12325.0
STAT4	-12336.0
BTN3A3	-12339.0
CCL2	-12341.0
KLRF1	-12343.0
RHOF	-12344.0
CD247	-12345.0
IL2RB	-12347.0
KIF22	-12358.0
SH2D1B	-12360.0
BTN3A1	-12362.0
PLD4	-12365.0
NCR1	-12370.0
FASLG	-12371.0

---

Membrane Trafficking

Membrane Trafficking

	632
set	Membrane Trafficking
setSize	559
pANOVA	5.33e-36
s.dist	0.309
p.adjustANOVA	1.82e-33

Top enriched genes

Top 20 genes

GeneID	Gene Rank
VAMP7	9499
F5	9485
RAB32	9463
RAB13	9440
PLIN3	9437
GNS	9360
RAB31	9356
GRB2	9304
TBC1D2	9301
ITSN1	9289
AP1S1	9286
YWHAG	9264
AGFG1	9211
ARF4	9191
PLA2G4A	9180
APP	9177
SORT1	9171
SERPINA1	9168
DCTN2	9157
SPTB	9154

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
VAMP7	9499
F5	9485
RAB32	9463
RAB13	9440
PLIN3	9437
GNS	9360
RAB31	9356
GRB2	9304
TBC1D2	9301
ITSN1	9289
AP1S1	9286
YWHAG	9264
AGFG1	9211
ARF4	9191
PLA2G4A	9180
APP	9177
SORT1	9171
SERPINA1	9168
DCTN2	9157
SPTB	9154
CD55	9145
KDELR1	9142
SBF2	9078
ARF1	9064
RAB1A	9052
YWHAE	9045
GABARAPL2	9044
PICALM	9022
RAB3IL1	9005
CLTC	9000
CUX1	8986
CTSZ	8975
CLTCL1	8965
RAB10	8926
STX10	8921
TBC1D14	8897
ARPC1A	8894
TGFA	8889
CHMP4B	8866
GALNT2	8843
NSF	8829
CPD	8824
RALGAPA2	8804
RAC1	8793
CHMP2A	8780
ANK1	8771
EXOC6	8762
BICD2	8746
RAB7A	8742
AP1B1	8730
TGOLN2	8714
UBAP1	8701
RAB11A	8688
ARPC5	8686
FTL	8665
RAB5C	8655
YWHAH	8649
BLOC1S1	8630
SNAP23	8628
AP2M1	8627
CAPZA2	8597
FNBP1L	8551
AMPH	8532
ARRB2	8490
RAB27A	8411
DCTN4	8387
CLTA	8376
COPA	8366
AP3B1	8365
RIN2	8355
CHMP3	8349
RAB1B	8313
KIF3C	8306
ARPC3	8277
HIP1	8258
KIF5B	8239
VAMP3	8222
KIF1B	8184
EGF	8179
REPS2	8154
RAB6A	8148
CAPZA1	8135
RAB3A	8133
PACSIN2	8123
SEC24D	8115
DAB2	8112
TBC1D10B	8078
EPN1	8045
MAP1LC3B	8043
TOR1A	8033
AP2S1	8026
CAPZB	8015
VPS37C	8010
GJD3	7996
TMED7	7950
RAB4A	7941
DENND3	7938
MAN1A1	7927
STX6	7906
GABARAP	7904
COPB2	7902
ARF5	7885
AP3S1	7874
ACTR2	7870
SNX2	7861
ACTR3	7818
FCHO2	7807
TRAPPC1	7806
RAB18	7801
KIF1C	7799
TSG101	7786
CNIH1	7779
DENND5A	7736
DYNC1I2	7735
ARF3	7732
KDELR2	7728
SEC24A	7660
VPS25	7638
SH3GL1	7625
ACTR10	7605
RIN1	7602
SPTA1	7595
COPG2	7594
VPS54	7568
ARPC4	7516
RHOQ	7511
COPG1	7509
CBL	7480
RABGEF1	7466
SNAPIN	7443
DENND1A	7441
NAA38	7435
STXBP3	7424
MVB12A	7400
ARPC2	7390
KLC3	7377
SEC23A	7335
COPB1	7321
DCTN6	7300
GDI2	7282
RAB33B	7267
AP2A2	7257
TMED9	7167
STX5	7166
TFG	7160
IGF2R	7149
ULK1	7125
TRAPPC3	7114
RAB39A	7113
RAB5A	7103
MCFD2	7099
RAB14	7095
LMAN2	7080
SURF4	7058
DNM3	7045
TBC1D1	7034
F8	7022
SNX18	7017
ACTR1A	7002
PAFAH1B2	6942
DYNC1LI1	6941
LMAN2L	6937
COPE	6896
AP2A1	6832
RIC1	6824
PPP6C	6819
BLOC1S6	6815
GAPVD1	6799
DNASE2	6745
TRAPPC8	6735
AP1M1	6711
MYO5A	6693
RAB5B	6690
MYH9	6685
UBB	6639
MAN2A2	6625
MON1B	6612
GORASP1	6606
GRK3	6593
COPS7A	6590
RAB8B	6529
GALNT1	6508
NEDD8	6482
SAR1B	6479
VPS37A	6467
TBC1D7	6452
OCRL	6442
RAB43	6433
AP4E1	6419
SNAP29	6390
YWHAB	6385
PREB	6368
TRAPPC12	6310
COL7A1	6304
SYNJ1	6296
GOLGA2	6203
VTA1	6185
LDLR	6183
SH3KBP1	6173
RAB21	6165
STAM2	6159
COPS2	6139
DNM2	6089
CYTH4	6085
CLTB	6084
GRK2	6068
RAB6B	6053
TMED2	6052
COPS3	6005
KIF13B	5998
DCTN3	5994
AREG	5977
SNF8	5973
DYNLL1	5952
UBQLN2	5939
CTTN	5930
DENND2C	5898
SEC22B	5873
CD59	5859
YIPF6	5857
ACBD3	5816
RAB3GAP1	5768
SEC13	5748
GDI1	5739
CHMP2B	5714
EXOC1	5670
RAB36	5636
YWHAZ	5624
HPS1	5605
EXOC4	5591
ARCN1	5580
MIA2	5574
KLC1	5523
KIF23	5510
TMEM115	5508
CHMP6	5499
PRKAG1	5476
PAFAH1B1	5470
TRAPPC9	5333
GOLGA5	5322
TRAPPC11	5319
VTI1A	5302
GOLIM4	5271
PPP6R1	5263
SCARB2	5255
VAMP8	5218
VPS4B	5212
YKT6	5205
TRAPPC5	5191
MVB12B	5175
UBQLN1	5108
KIF20A	5096
DCTN1	5078
ITSN2	5060
SYT1	5056
HBEGF	5013
CHMP5	4943
EXOC7	4924
FTH1	4902
AGPAT3	4809
GJB6	4761
EXOC3	4724
STX18	4648
DNAJC6	4640
SEC16A	4619
RGP1	4538
HGS	4513
UBC	4439
RABEPK	4434
USP6NL	4433
RAB3GAP2	4429
PAFAH1B3	4417
RAB11B	4402
COPS5	4361
DYNC1LI2	4273
COG7	4269
KIF9	4253
CCZ1	4242
VPS28	4199
DYNC1I1	4187
USO1	4154
TRAPPC6B	4147
EXOC5	4141
NAPG	4139
EPS15	4138
RAB9A	4088
COPZ1	4035
AP1G1	3987
RAB35	3981
VPS37B	3908
RAB8A	3880
GGA3	3816
CLINT1	3815
TBC1D13	3782
KIF3B	3740
STX16	3717
ARFGAP3	3714
TBC1D15	3665
EPS15L1	3655
AKT1	3614
SEC24B	3608
DNM1	3587
KIF4A	3585
STON2	3569
SCFD1	3525
PIP5K1C	3419
TBC1D16	3409
NECAP2	3387
RAB27B	3386
MYO1C	3310
PPP6R3	3261
PUM1	3250
RAB3IP	3237
TBC1D24	3200
VAMP4	3191
ALS2	3176
KIAA0319	3163
DENND4B	3139
DENND6B	2993
RACGAP1	2848
KIF16B	2785
GCC1	2730
TMED3	2720
RALA	2710
EPGN	2662
STON1	2574
GAK	2570
KIF27	2549
TMF1	2535
VPS45	2496
CFTR	2416
GOLGA1	2415
CHMP4A	2400
CSNK1D	2390
TRIP10	2343
CTSC	2326
GGA1	2310
CHM	2273
NECAP1	2220
RABGAP1	2052
PRKAG2	2015
ARRB1	1998
EREG	1888
AP1M2	1832
COPS4	1776
COPS6	1637
SFN	1615
TFRC	1524
NAPA	1432
TBC1D8B	1417
ARF6	1377
LRP2	1307
PRKAB1	1302
STAM	1285
KIF6	1147
UBA52	1121
TF	1102
SEC31A	1099
GJC2	1083
DTNBP1	1014
CCZ1B	990
USE1	938
KIF11	787
VPS4A	784
KIF2C	726
CNIH2	654
STX4	606
GJC1	518
SYT2	461
CYTH2	442
AKT2	433
TXNDC5	393
SYS1	386
CENPE	332
SEC16B	330
TMED10	323
WASL	299
AVPR2	291
NBAS	208
ANKRD27	186
AP4M1	138
ZW10	31
EXOC8	-1
COG4	-6
TBC1D20	-18
TBC1D3	-66
KIF18B	-143
GOSR1	-182
KIFC1	-249
FNBP1	-311
VPS53	-341
COG8	-346
SNX9	-430
SEC23IP	-468
DENND6A	-562
TRIP11	-579
BET1	-594
TSC2	-804
RAB12	-856
SCOC	-885
KIF2A	-1069
MAN2A1	-1349
GOSR2	-1456
CHML	-1515
RAB7B	-1531
KIFC2	-1642
ARFGAP1	-1942
MAN1A2	-2055
CALM1	-2081
KDELR3	-2117
TSC1	-2118
TOR1B	-2136
AP1S2	-2261
TRAPPC2L	-2299
FCHO1	-2392
TRAPPC13	-2479
SEC24C	-2569
AP2B1	-2709
KIF18A	-2742
NAPB	-2780
MON1A	-2910
ARFIP2	-3197
KIF15	-3249
COG5	-3259
SNX5	-3305
SPTBN5	-3531
TPD52L1	-3542
VPS52	-3619
RAB41	-3974
DYNLL2	-3980
SH3D19	-4011
GOLGA4	-4064
DCTN5	-4086
EPN2	-4100
RALGAPB	-4138
SEC22C	-4248
DENND5B	-4249
GBF1	-4290
GPS1	-4517
ANK3	-4919
KIF26A	-4925
GJA3	-4935
SEC22A	-5052
ARL1	-5063
SPTBN2	-5129
ASPSCR1	-5154
PIK3C2A	-5194
GOLGB1	-5370
CD4	-5406
COG3	-5426
AP1S3	-5522
DENND4A	-5540
AP1G2	-5590
AP4S1	-5731
ARFGAP2	-5786
COG6	-5811
MIA3	-6245
ANKRD28	-6250
TJP1	-6374
RAB9B	-6552
VPS51	-6584
GGA2	-6587
KIF21B	-6702
TRAPPC4	-6712
SYT11	-6763
KIF28P	-6770
MAN1C1	-6804
VPS36	-6848
RPS27A	-6938
REPS1	-7137
AP4B1	-7235
YWHAQ	-7340
BICD1	-7365
TBC1D25	-7372
DENND1C	-7377
BET1L	-7405
BLOC1S4	-7493
ARFRP1	-7561
C2CD5	-7570
DENND4C	-7574
BNIP1	-7588
DYNC1H1	-7685
GCC2	-7725
SPTBN1	-7764
EXOC2	-7780
KIF20B	-7822
COG2	-7917
PRKAB2	-8172
CYTH3	-8200
ALS2CL	-8315
DENND2A	-8355
KLC4	-8376
SYNJ2	-8511
M6PR	-8519
KIFAP3	-8619
BLOC1S3	-8703
TRAPPC2	-8704
RAB38	-8714
TBC1D17	-8716
COPS8	-8755
CHMP7	-8802
SRC	-8820
KIF5C	-8865
KIF5A	-8869
CNIH3	-9011
KLC2	-9059
AAK1	-9190
DENND1B	-9284
LDLRAP1	-9326
TRAPPC10	-9369
LNPEP	-9618
TPD52	-9644
NAA30	-9696
COPS7B	-9775
RAB30	-9844
POLG	-9889
SYTL1	-10104
RINT1	-10112
RINL	-10326
SBF1	-10530
IL7R	-10546
HIP1R	-10615
LMAN1	-10630
TBC1D4	-10754
COPZ2	-10863
TRAPPC6A	-10917
HSPA8	-10922
RAB33A	-10940
STX17	-11006
DVL2	-11152
RHOBTB3	-11172
CD3D	-11401
MYO6	-11410
BIN1	-11411
SPTAN1	-11426
NAA35	-11524
CD3G	-11526
RAB39B	-11529
HPS4	-11558
FZD4	-11650
KIF26B	-11663
KIF19	-11733
SLC2A8	-11749
RABEP1	-11754
OPTN	-11766
VAMP2	-11779
KIF21A	-11837
AKT3	-11849
TBC1D10C	-11861
ADRB2	-11892
MADD	-11899
KIF3A	-11972
TBC1D10A	-12025
PLA2G6	-12122
COG1	-12125
DENND2D	-12293
CYTH1	-12314
KIF22	-12358
PACSIN1	-12374

---

Vesicle-mediated transport

Vesicle-mediated transport

	1314
set	Vesicle-mediated transport
setSize	650
pANOVA	1.64e-31
s.dist	0.268
p.adjustANOVA	4.49e-29

Top enriched genes

Top 20 genes

GeneID	Gene Rank
VAMP7	9499
STAB1	9495
F5	9485
RAB32	9463
CD163	9462
HP	9454
CD36	9444
RAB13	9440
PLIN3	9437
GNS	9360
RAB31	9356
GRB2	9304
TBC1D2	9301
ITSN1	9289
AP1S1	9286
YWHAG	9264
AGFG1	9211
ARF4	9191
PLA2G4A	9180
APP	9177

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
VAMP7	9499
STAB1	9495
F5	9485
RAB32	9463
CD163	9462
HP	9454
CD36	9444
RAB13	9440
PLIN3	9437
GNS	9360
RAB31	9356
GRB2	9304
TBC1D2	9301
ITSN1	9289
AP1S1	9286
YWHAG	9264
AGFG1	9211
ARF4	9191
PLA2G4A	9180
APP	9177
SORT1	9171
SERPINA1	9168
DCTN2	9157
SPTB	9154
CD55	9145
KDELR1	9142
LRP1	9080
SBF2	9078
ARF1	9064
HBB	9054
RAB1A	9052
YWHAE	9045
GABARAPL2	9044
PICALM	9022
RAB3IL1	9005
CLTC	9000
HBA1	8990
CUX1	8986
CTSZ	8975
CLTCL1	8965
RAB10	8926
STX10	8921
TBC1D14	8897
ARPC1A	8894
TGFA	8889
CHMP4B	8866
GALNT2	8843
NSF	8829
CPD	8824
RALGAPA2	8804
RAC1	8793
CHMP2A	8780
ANK1	8771
EXOC6	8762
BICD2	8746
RAB7A	8742
AP1B1	8730
TGOLN2	8714
UBAP1	8701
RAB11A	8688
ARPC5	8686
FTL	8665
RAB5C	8655
YWHAH	8649
BLOC1S1	8630
SNAP23	8628
AP2M1	8627
CAPZA2	8597
FNBP1L	8551
AMPH	8532
ARRB2	8490
RAB27A	8411
DCTN4	8387
CLTA	8376
COPA	8366
AP3B1	8365
RIN2	8355
CHMP3	8349
MARCO	8329
RAB1B	8313
KIF3C	8306
ARPC3	8277
HIP1	8258
KIF5B	8239
VAMP3	8222
KIF1B	8184
EGF	8179
REPS2	8154
RAB6A	8148
CAPZA1	8135
RAB3A	8133
PACSIN2	8123
SEC24D	8115
DAB2	8112
TBC1D10B	8078
EPN1	8045
MAP1LC3B	8043
TOR1A	8033
AP2S1	8026
CAPZB	8015
VPS37C	8010
GJD3	7996
TMED7	7950
RAB4A	7941
DENND3	7938
MAN1A1	7927
STX6	7906
GABARAP	7904
COPB2	7902
ARF5	7885
AP3S1	7874
ACTR2	7870
SNX2	7861
ACTR3	7818
FCHO2	7807
TRAPPC1	7806
RAB18	7801
KIF1C	7799
TSG101	7786
CNIH1	7779
DENND5A	7736
DYNC1I2	7735
ARF3	7732
KDELR2	7728
SEC24A	7660
VPS25	7638
SH3GL1	7625
ACTR10	7605
RIN1	7602
SPTA1	7595
COPG2	7594
VPS54	7568
ARPC4	7516
RHOQ	7511
COPG1	7509
CBL	7480
RABGEF1	7466
SNAPIN	7443
DENND1A	7441
NAA38	7435
STXBP3	7424
MVB12A	7400
ARPC2	7390
KLC3	7377
SPARC	7339
SEC23A	7335
COPB1	7321
DCTN6	7300
GDI2	7282
RAB33B	7267
AP2A2	7257
TMED9	7167
STX5	7166
TFG	7160
IGF2R	7149
ULK1	7125
TRAPPC3	7114
RAB39A	7113
RAB5A	7103
MCFD2	7099
RAB14	7095
LMAN2	7080
SURF4	7058
DNM3	7045
TBC1D1	7034
F8	7022
SNX18	7017
ACTR1A	7002
PAFAH1B2	6942
DYNC1LI1	6941
LMAN2L	6937
COPE	6896
AP2A1	6832
RIC1	6824
PPP6C	6819
BLOC1S6	6815
GAPVD1	6799
DNASE2	6745
TRAPPC8	6735
AP1M1	6711
MYO5A	6693
RAB5B	6690
MYH9	6685
UBB	6639
MAN2A2	6625
MON1B	6612
GORASP1	6606
GRK3	6593
COPS7A	6590
RAB8B	6529
GALNT1	6508
NEDD8	6482
SAR1B	6479
VPS37A	6467
TBC1D7	6452
OCRL	6442
RAB43	6433
AP4E1	6419
SNAP29	6390
YWHAB	6385
PREB	6368
CALR	6340
TRAPPC12	6310
COL7A1	6304
SYNJ1	6296
GOLGA2	6203
VTA1	6185
LDLR	6183
SH3KBP1	6173
RAB21	6165
STAM2	6159
COPS2	6139
DNM2	6089
CYTH4	6085
CLTB	6084
GRK2	6068
RAB6B	6053
TMED2	6052
COPS3	6005
KIF13B	5998
DCTN3	5994
AREG	5977
SNF8	5973
SCARB1	5962
DYNLL1	5952
UBQLN2	5939
CTTN	5930
DENND2C	5898
SEC22B	5873
CD59	5859
YIPF6	5857
ACBD3	5816
RAB3GAP1	5768
SEC13	5748
GDI1	5739
CHMP2B	5714
EXOC1	5670
RAB36	5636
YWHAZ	5624
HPS1	5605
EXOC4	5591
ARCN1	5580
MIA2	5574
STAB2	5569
KLC1	5523
KIF23	5510
TMEM115	5508
CHMP6	5499
PRKAG1	5476
PAFAH1B1	5470
TRAPPC9	5333
GOLGA5	5322
TRAPPC11	5319
VTI1A	5302
GOLIM4	5271
PPP6R1	5263
SCARB2	5255
VAMP8	5218
VPS4B	5212
YKT6	5205
TRAPPC5	5191
MVB12B	5175
UBQLN1	5108
KIF20A	5096
DCTN1	5078
ITSN2	5060
SYT1	5056
HBEGF	5013
CHMP5	4943
EXOC7	4924
FTH1	4902
AGPAT3	4809
GJB6	4761
EXOC3	4724
STX18	4648
DNAJC6	4640
SEC16A	4619
RGP1	4538
HGS	4513
UBC	4439
RABEPK	4434
USP6NL	4433
RAB3GAP2	4429
PAFAH1B3	4417
RAB11B	4402
COPS5	4361
DYNC1LI2	4273
COG7	4269
KIF9	4253
CCZ1	4242
VPS28	4199
DYNC1I1	4187
USO1	4154
TRAPPC6B	4147
EXOC5	4141
NAPG	4139
EPS15	4138
RAB9A	4088
COPZ1	4035
AP1G1	3987
RAB35	3981
VPS37B	3908
RAB8A	3880
GGA3	3816
CLINT1	3815
TBC1D13	3782
KIF3B	3740
STX16	3717
ARFGAP3	3714
ALB	3668
TBC1D15	3665
EPS15L1	3655
AKT1	3614
SEC24B	3608
DNM1	3587
KIF4A	3585
STON2	3569
SCFD1	3525
PIP5K1C	3419
TBC1D16	3409
NECAP2	3387
RAB27B	3386
MYO1C	3310
PPP6R3	3261
PUM1	3250
RAB3IP	3237
TBC1D24	3200
VAMP4	3191
ALS2	3176
KIAA0319	3163
DENND4B	3139
DENND6B	2993
RACGAP1	2848
KIF16B	2785
GCC1	2730
TMED3	2720
RALA	2710
EPGN	2662
STON1	2574
GAK	2570
KIF27	2549
TMF1	2535
VPS45	2496
COL1A2	2469
CFTR	2416
GOLGA1	2415
CHMP4A	2400
CSNK1D	2390
TRIP10	2343
CTSC	2326
GGA1	2310
CHM	2273
NECAP1	2220
HSP90B1	2059
RABGAP1	2052
PRKAG2	2015
ARRB1	1998
EREG	1888
AP1M2	1832
COPS4	1776
COPS6	1637
SFN	1615
TFRC	1524
NAPA	1432
TBC1D8B	1417
ARF6	1377
HSP90AA1	1326
LRP2	1307
PRKAB1	1302
STAM	1285
KIF6	1147
UBA52	1121
TF	1102
SEC31A	1099
GJC2	1083
DTNBP1	1014
CCZ1B	990
COL4A2	970
USE1	938
KIF11	787
VPS4A	784
MSR1	772
SCARF1	745
KIF2C	726
CNIH2	654
STX4	606
GJC1	518
SYT2	461
CYTH2	442
AKT2	433
TXNDC5	393
SYS1	386
IGHV1-2	360
CENPE	332
SEC16B	330
TMED10	323
WASL	299
AVPR2	291
IGHV2-5	230
APOE	218
NBAS	208
ANKRD27	186
AP4M1	138
IGHV3-53	103
ZW10	31
EXOC8	-1
COG4	-6
TBC1D20	-18
TBC1D3	-66
HYOU1	-113
KIF18B	-143
GOSR1	-182
KIFC1	-249
FNBP1	-311
VPS53	-341
COG8	-346
SNX9	-430
IGHV3-7	-441
SEC23IP	-468
DENND6A	-562
TRIP11	-579
BET1	-594
IGHV1-46	-618
IGHV3-48	-668
IGKV3-11	-781
TSC2	-804
RAB12	-856
SCOC	-885
IGKV1-39	-989
IGLV7-46	-1016
KIF2A	-1069
SCGB3A2	-1154
IGKV1-5	-1184
HPX	-1199
IGHA2	-1274
IGLV2-8	-1294
IGKV5-2	-1298
IGHV3-23	-1317
MAN2A1	-1349
IGHV3-13	-1443
GOSR2	-1456
CHML	-1515
IGLV2-18	-1524
IGKV1-16	-1528
RAB7B	-1531
IGLV4-69	-1559
IGKV1D-39	-1574
KIFC2	-1642
IGHV1-69	-1822
IGLV10-54	-1884
ARFGAP1	-1942
IGLV1-36	-2030
IGKV2-30	-2045
MAN1A2	-2055
CALM1	-2081
IGLV7-43	-2089
IGLV3-19	-2111
KDELR3	-2117
TSC1	-2118
IGHV3-11	-2134
TOR1B	-2136
AP1S2	-2261
IGHA1	-2291
IGKV3-15	-2297
TRAPPC2L	-2299
FCHO1	-2392
IGKV1-33	-2424
TRAPPC13	-2479
IGHV3-30	-2484
IGKV4-1	-2532
SEC24C	-2569
AP2B1	-2709
KIF18A	-2742
NAPB	-2780
IGKV1-17	-2871
IGLV2-23	-2878
IGLV6-57	-2885
IGHV4-59	-2892
IGLV2-11	-2905
MON1A	-2910
IGHV3-33	-2988
IGHV4-34	-3016
IGKV3-20	-3085
IGHV2-70	-3138
ARFIP2	-3197
KIF15	-3249
IGLV1-44	-3258
COG5	-3259
SNX5	-3305
SPTBN5	-3531
TPD52L1	-3542
VPS52	-3619
IGKV3D-20	-3894
RAB41	-3974
DYNLL2	-3980
SH3D19	-4011
GOLGA4	-4064
DCTN5	-4086
EPN2	-4100
RALGAPB	-4138
IGLV3-1	-4159
JCHAIN	-4240
SEC22C	-4248
DENND5B	-4249
GBF1	-4290
COLEC12	-4367
IGKC	-4428
GPS1	-4517
IGHV4-39	-4582
IGLV3-21	-4735
IGLV1-40	-4788
ANK3	-4919
KIF26A	-4925
IGLV3-25	-4933
GJA3	-4935
IGLV1-51	-4956
SEC22A	-5052
ARL1	-5063
SPTBN2	-5129
ASPSCR1	-5154
PIK3C2A	-5194
IGLC7	-5281
GOLGB1	-5370
CD4	-5406
COG3	-5426
IGLV8-61	-5427
IGKV1-12	-5446
IGLC3	-5477
IGLC2	-5510
AP1S3	-5522
DENND4A	-5540
AP1G2	-5590
SSC5D	-5595
IGKV2D-28	-5634
AP4S1	-5731
ARFGAP2	-5786
IGKV2-28	-5808
COG6	-5811
IGLV5-45	-5869
IGLV3-27	-5874
IGLV1-47	-6018
IGLC1	-6157
MIA3	-6245
ANKRD28	-6250
TJP1	-6374
RAB9B	-6552
VPS51	-6584
GGA2	-6587
KIF21B	-6702
TRAPPC4	-6712
SYT11	-6763
KIF28P	-6770
MAN1C1	-6804
VPS36	-6848
RPS27A	-6938
REPS1	-7137
AP4B1	-7235
YWHAQ	-7340
IGLV3-12	-7358
BICD1	-7365
TBC1D25	-7372
DENND1C	-7377
BET1L	-7405
BLOC1S4	-7493
ARFRP1	-7561
C2CD5	-7570
DENND4C	-7574
BNIP1	-7588
APOL1	-7657
DYNC1H1	-7685
GCC2	-7725
SPTBN1	-7764
EXOC2	-7780
KIF20B	-7822
COG2	-7917
PRKAB2	-8172
CYTH3	-8200
ALS2CL	-8315
IGLV2-14	-8345
DENND2A	-8355
KLC4	-8376
SYNJ2	-8511
M6PR	-8519
KIFAP3	-8619
BLOC1S3	-8703
TRAPPC2	-8704
RAB38	-8714
TBC1D17	-8716
COPS8	-8755
CHMP7	-8802
SRC	-8820
KIF5C	-8865
KIF5A	-8869
CNIH3	-9011
KLC2	-9059
AAK1	-9190
DENND1B	-9284
LDLRAP1	-9326
TRAPPC10	-9369
HSPH1	-9407
LNPEP	-9618
TPD52	-9644
NAA30	-9696
COPS7B	-9775
RAB30	-9844
POLG	-9889
SYTL1	-10104
RINT1	-10112
RINL	-10326
SBF1	-10530
IL7R	-10546
HIP1R	-10615
LMAN1	-10630
TBC1D4	-10754
COPZ2	-10863
TRAPPC6A	-10917
HSPA8	-10922
RAB33A	-10940
STX17	-11006
DVL2	-11152
RHOBTB3	-11172
CD3D	-11401
MYO6	-11410
BIN1	-11411
SPTAN1	-11426
NAA35	-11524
CD3G	-11526
RAB39B	-11529
HPS4	-11558
FZD4	-11650
KIF26B	-11663
KIF19	-11733
SLC2A8	-11749
RABEP1	-11754
OPTN	-11766
VAMP2	-11779
KIF21A	-11837
AKT3	-11849
TBC1D10C	-11861
ADRB2	-11892
MADD	-11899
KIF3A	-11972
TBC1D10A	-12025
SCARA5	-12055
PLA2G6	-12122
COG1	-12125
DENND2D	-12293
CYTH1	-12314
KIF22	-12358
PACSIN1	-12374

---

Signal Transduction

Signal Transduction

	1071
set	Signal Transduction
setSize	1894
pANOVA	7.04e-28
s.dist	0.152
p.adjustANOVA	1.6e-25

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CSF2RA	9526
PPARG	9522
WASF1	9520
S100A9	9516
FZD5	9513
EDNRB	9512
S100A8	9503
PLB1	9490
SOCS3	9476
GPER1	9475
XK	9468
HRH2	9466
GNA15	9452
CCR2	9449
GRB10	9439
CTSD	9433
PRKACA	9429
ATP6V0A1	9423
NUMB	9414
LAMTOR1	9411

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CSF2RA	9526.0
PPARG	9522.0
WASF1	9520.0
S100A9	9516.0
FZD5	9513.0
EDNRB	9512.0
S100A8	9503.0
PLB1	9490.0
SOCS3	9476.0
GPER1	9475.0
XK	9468.0
HRH2	9466.0
GNA15	9452.0
CCR2	9449.0
GRB10	9439.0
CTSD	9433.0
PRKACA	9429.0
ATP6V0A1	9423.0
NUMB	9414.0
LAMTOR1	9411.0
LAMC1	9387.0
ADM	9378.0
H2AJ	9374.0
RHOT1	9367.0
MYO7A	9361.0
RASGRP4	9359.0
PTAFR	9355.0
GNG10	9349.0
CTNNA1	9341.0
GPR27	9340.0
TACC3	9331.0
SNX3	9326.0
ARHGEF11	9305.0
GRB2	9304.0
ATP6V1A	9302.0
FPR1	9295.0
FSTL3	9290.0
ITSN1	9289.0
H2BC21	9283.0
DUSP3	9280.0
TNFRSF1A	9270.0
NCF4	9268.0
CYFIP1	9265.0
YWHAG	9264.0
TNS3	9262.0
ARPC1B	9259.0
ATP6V0D1	9245.0
FES	9237.0
WNT11	9215.0
NCF2	9190.0
UBE2D1	9187.0
NCSTN	9186.0
PLA2G4A	9180.0
APP	9177.0
RTN4	9159.0
SPTB	9154.0
KREMEN1	9149.0
CD55	9145.0
ACVR1B	9135.0
GPR84	9133.0
C5AR1	9129.0
ATP6V0C	9127.0
RIT1	9121.0
MAPK14	9104.0
FRAT2	9096.0
FPR2	9095.0
FKBP5	9091.0
LRP1	9080.0
SYK	9076.0
FURIN	9075.0
RCOR1	9073.0
TNFRSF10D	9072.0
AGO4	9070.0
MAP2K1	9063.0
ATP6V1B2	9057.0
FKBP1A	9056.0
H2BC12	9051.0
ATP6V1D	9047.0
YWHAE	9045.0
PHC2	9043.0
PIK3CB	9038.0
VAPA	9033.0
CYBB	9031.0
CARM1	9020.0
ACTB	9011.0
PRKCD	9008.0
DLG4	9007.0
CLTC	9000.0
STK3	8995.0
GNAQ	8993.0
ADCY3	8984.0
KL	8963.0
HDAC4	8960.0
MAML3	8957.0
MAPK3	8953.0
FGD4	8948.0
PLCB3	8916.0
ALDH1A2	8914.0
CRK	8906.0
OS9	8898.0
ARPC1A	8894.0
ITGA2B	8893.0
TGFA	8889.0
CDC42EP3	8880.0
ZDHHC9	8872.0
PLPPR2	8868.0
CCR1	8865.0
HGF	8863.0
ARHGAP18	8852.0
MEMO1	8847.0
CDKN2B	8836.0
MKRN1	8817.0
GNG5	8815.0
PROK2	8806.0
NTSR1	8805.0
RHOU	8794.0
RAC1	8793.0
ADAM10	8791.0
FOSL1	8788.0
LTB4R	8787.0
STRADB	8773.0
RBPJ	8770.0
RRAGD	8753.0
APBB1IP	8744.0
JAG1	8743.0
PCSK6	8740.0
ARHGEF40	8723.0
SUFU	8718.0
ADGRE1	8715.0
FRAT1	8712.0
BCL2L1	8700.0
MARK3	8697.0
RNF146	8696.0
ARPC5	8686.0
FOXO3	8682.0
H3-3A	8661.0
YWHAH	8649.0
SNAI1	8645.0
UBE2D3	8640.0
ARHGDIB	8639.0
ZDHHC7	8636.0
IQCE	8634.0
AP2M1	8627.0
CDK5	8616.0
CDH5	8613.0
PRKAR1A	8607.0
ATP6V0B	8598.0
ATP6V0E1	8596.0
MYL6	8576.0
IRS2	8569.0
ACTG1	8562.0
WAS	8560.0
TLE3	8558.0
SOCS6	8557.0
CLIP1	8540.0
ATP6V1C1	8539.0
TLN1	8525.0
DIAPH2	8523.0
ACVRL1	8519.0
SMAD1	8511.0
LAMTOR5	8498.0
F2RL1	8495.0
ARRB2	8490.0
DLC1	8488.0
RHOG	8487.0
PSMB7	8485.0
OR2W3	8484.0
TFDP1	8470.0
PTEN	8460.0
SPINT1	8446.0
P4HB	8440.0
ADORA2B	8437.0
RALB	8414.0
BAMBI	8405.0
PSMD4	8402.0
RNF41	8389.0
PTGFR	8385.0
SPOPL	8384.0
MAPKAPK3	8382.0
CLTA	8376.0
REEP4	8375.0
WASF2	8369.0
ARHGAP26	8368.0
MRTFA	8350.0
BAG4	8328.0
TNFRSF10B	8321.0
RHOA	8319.0
SOS2	8299.0
GNB1	8294.0
ITGB3	8291.0
FN1	8284.0
INSR	8282.0
ARPC3	8277.0
CAB39	8276.0
OMG	8272.0
ECE1	8271.0
TAX1BP3	8262.0
PSME3	8251.0
MOB1A	8240.0
KIF5B	8239.0
PPP2CA	8234.0
HEBP1	8232.0
PAK1	8230.0
ARAP3	8225.0
LYL1	8221.0
JAK3	8219.0
SPINT2	8206.0
PPM1A	8200.0
SP1	8193.0
C5AR2	8187.0
CFL1	8186.0
PAK2	8185.0
EGF	8179.0
PPP3R1	8175.0
MKNK1	8170.0
B9D2	8168.0
ATP6AP1	8160.0
IQGAP1	8152.0
PTPN12	8151.0
RAB6A	8148.0
LYPLA1	8143.0
TRIM27	8142.0
GNB2	8141.0
MYD88	8136.0
IL6R	8132.0
CAMKK2	8125.0
ADAM17	8110.0
WLS	8104.0
PSMB5	8101.0
GAB2	8099.0
STAT3	8098.0
ARHGAP29	8084.0
GNAI2	8075.0
LIMK2	8074.0
ATP6V1H	8064.0
F11R	8058.0
EPN1	8045.0
ATP2A2	8038.0
ATP6V1E1	8035.0
EIF4G1	8031.0
AP2S1	8026.0
DOK1	8022.0
P2RY13	8016.0
WWP2	8013.0
C3AR1	8012.0
MEF2A	8009.0
H2BC5	8003.0
REEP5	7989.0
NCOR2	7985.0
CHUK	7966.0
PSEN1	7961.0
DGKG	7958.0
GNAI3	7953.0
RHOBTB1	7943.0
RAB4A	7941.0
PTK2B	7935.0
H2AC6	7934.0
PRKAR1B	7918.0
H2BC11	7912.0
KDM4B	7911.0
GNAS	7909.0
FSTL1	7908.0
MAPK6	7903.0
NOTCH3	7899.0
VAV1	7896.0
TBL1X	7887.0
EPAS1	7886.0
RAF1	7879.0
NEDD4L	7875.0
ACTR2	7870.0
OPRL1	7866.0
AKT1S1	7865.0
GMIP	7856.0
P2RY1	7852.0
PSMD6	7846.0
ANXA1	7842.0
SMAD6	7835.0
ACTR3	7818.0
ARAP1	7817.0
USP4	7812.0
PIK3AP1	7811.0
LYN	7809.0
PTPRJ	7783.0
CSNK1A1	7766.0
GSK3A	7760.0
ARHGAP19	7756.0
DYNC1I2	7735.0
RGS19	7734.0
PPP2CB	7712.0
MYL9	7703.0
RPS6KA1	7695.0
MGLL	7694.0
BEX3	7689.0
CASP9	7685.0
NCKAP1L	7673.0
RHEB	7669.0
CSF2RB	7661.0
MAPRE1	7658.0
SPHK1	7657.0
LRRK2	7654.0
ZFYVE16	7649.0
RGL1	7647.0
TRIB1	7643.0
NDEL1	7627.0
MAP3K11	7626.0
SH3GL1	7625.0
TFF3	7621.0
PSMD9	7620.0
PTPN2	7615.0
CFLAR	7610.0
SH2B2	7609.0
SPTA1	7595.0
RGS2	7577.0
LAMTOR3	7574.0
CTNNBIP1	7569.0
LAMTOR2	7567.0
POLR2E	7563.0
ADAP1	7557.0
TEC	7549.0
CDC42	7537.0
RUNX1	7529.0
ARHGAP24	7523.0
RGL2	7520.0
ARPC4	7516.0
RHOQ	7511.0
PTCRA	7507.0
LAMB3	7497.0
RXRA	7495.0
MAPK1	7493.0
ROCK1	7489.0
CCND3	7487.0
SERPINE1	7483.0
CBL	7480.0
UBE2M	7477.0
PLXND1	7475.0
VEGFA	7467.0
IER3	7463.0
NCKAP1	7462.0
HIF1A	7436.0
ARHGAP6	7433.0
KLHL12	7429.0
NR1H2	7415.0
PSMD2	7411.0
PLEKHG2	7395.0
FAM13A	7392.0
ARPC2	7390.0
H2BC4	7389.0
BCL2L11	7384.0
KLC3	7377.0
CXCL16	7375.0
FRS3	7343.0
SPARC	7339.0
PLTP	7338.0
GNB4	7336.0
NCF1	7334.0
SHOC2	7333.0
PSMA1	7329.0
VCL	7328.0
DOCK1	7314.0
RAP1A	7305.0
DLD	7303.0
H2BC17	7285.0
GDI2	7282.0
PIK3R6	7270.0
AP2A2	7257.0
SPPL2A	7250.0
PSMD1	7241.0
ADGRE2	7236.0
RFNG	7233.0
OXER1	7229.0
EPOR	7223.0
MOB1B	7207.0
BTK	7206.0
FLT3	7196.0
FFAR2	7193.0
RXFP2	7189.0
TCIRG1	7188.0
PSMB3	7171.0
IL1RAP	7150.0
PSAP	7145.0
PRKCB	7097.0
PSMA7	7096.0
TYK2	7087.0
ABI1	7082.0
SRF	7079.0
CCRL2	7073.0
LRP10	7070.0
KIDINS220	7069.0
GTF2A2	7066.0
PPP1CB	7064.0
DNM3	7045.0
PARD3	7040.0
THBS3	7037.0
BRK1	7032.0
PSMC1	7021.0
REEP3	7016.0
PPP3CB	7005.0
GPR35	6986.0
TMED5	6984.0
RGS18	6972.0
STAT5A	6965.0
TAB2	6964.0
DUSP1	6950.0
RGS14	6948.0
DYNC1LI1	6941.0
SPRED2	6936.0
STAT5B	6925.0
CYBA	6922.0
GPSM3	6912.0
VEGFC	6906.0
PRKG1	6901.0
BAD	6892.0
VCP	6886.0
RAPGEF2	6867.0
CXCR1	6864.0
TLE4	6854.0
ARHGEF17	6852.0
SEL1L	6847.0
PPP1R14A	6839.0
AP2A1	6832.0
CUL3	6821.0
PSMB6	6813.0
WASF3	6808.0
NFKBIA	6807.0
JUNB	6806.0
STRAP	6805.0
RALBP1	6796.0
MAP2K2	6794.0
FLT1	6793.0
NLN	6785.0
PPP2R5B	6774.0
DTX2	6754.0
SRGAP1	6744.0
PRKAR2B	6741.0
GFAP	6713.0
ST3GAL6	6701.0
H3C15	6699.5
MYH9	6685.0
GNAT2	6683.0
POLR2J	6671.0
VPS35	6668.0
PSMF1	6659.0
E2F3	6650.0
VWF	6641.0
UBB	6639.0
SDC4	6637.0
PSMC6	6635.0
GSK3B	6634.0
VPS26A	6632.0
MYLK	6618.0
IQGAP2	6599.0
RGS16	6598.0
INSL3	6594.0
GRK3	6593.0
GRK6	6587.0
PSMD12	6556.0
ARHGEF2	6546.0
SREBF1	6539.0
GNG11	6495.0
LEPR	6485.0
NEDD8	6482.0
RDH11	6466.0
FZD2	6462.0
AHCYL1	6456.0
FFAR3	6455.0
PIP5K1B	6450.0
OCRL	6442.0
USF2	6440.0
RARA	6429.0
MYO9B	6424.0
USP8	6418.0
PREX1	6414.0
CTNNB1	6408.0
FOXO4	6391.0
CSNK2A2	6388.0
YWHAB	6385.0
KBTBD7	6376.0
PDE3A	6353.0
E2F1	6343.0
PPP1CC	6330.0
USP7	6323.0
LRP12	6321.0
CAMKK1	6317.0
OR52K1	6313.0
E2F4	6300.0
APH1B	6280.0
NFKB1	6277.0
ABR	6260.0
ELMO1	6258.0
ARHGAP9	6256.0
EEPD1	6251.0
RRAGA	6244.0
DHRS9	6236.0
PSMD11	6231.0
PXN	6230.0
PPP3CA	6217.0
SIRT6	6214.0
NEDD4	6201.0
CSNK2A1	6199.0
LDLR	6183.0
SH3KBP1	6173.0
SRGAP2	6171.0
PRKAR2A	6166.0
STAM2	6159.0
DTX4	6156.0
RGL3	6150.0
PTPN18	6149.0
USP15	6148.0
ROCK2	6138.0
PDPK1	6136.0
IRAK1	6131.0
EP300	6129.0
LATS2	6128.0
HDAC7	6122.0
PIP5K1A	6110.0
ABCA1	6109.0
ITGAV	6106.0
ARHGDIA	6104.0
ARHGEF37	6100.0
PTPN6	6096.0
DNM2	6089.0
RGS6	6086.0
CLTB	6084.0
FNTB	6081.0
EIF4EBP1	6072.0
GRK2	6068.0
TMED2	6052.0
PPP1R12A	6050.0
PIK3CD	6046.0
PPBP	6042.0
H2AZ1	6036.0
RLN3	6033.0
LPAR2	6032.0
TAX1BP1	6031.0
SHB	6026.0
FABP5	6021.0
ASH2L	6001.0
IGF1R	5990.0
PDGFC	5986.0
PPP1R15A	5981.0
AREG	5977.0
PSMA6	5970.0
LAMB1	5966.0
P2RY2	5965.0
PSMD7	5963.0
AMOTL1	5960.0
PTK6	5956.0
PDK4	5953.0
DYNLL1	5952.0
THBS1	5951.0
PSMD13	5948.0
OPN3	5942.0
CTTN	5930.0
BAX	5916.0
SUCNR1	5905.0
SHARPIN	5902.0
PPP2R5A	5897.0
NCOR1	5887.0
STAT6	5884.0
ADM2	5881.0
APOA2	5879.0
ATP6V1F	5878.0
PDE1B	5874.0
CXCR2	5861.0
PDGFRA	5858.0
ITPR2	5842.0
GRIN2D	5841.0
GNA13	5836.0
ARHGAP27	5830.0
CXCL1	5824.0
DAGLB	5820.0
RANBP9	5813.0
ADORA3	5799.0
ST3GAL4	5781.0
KEL	5775.0
OR2L2	5770.0
PSMD8	5757.0
RNF111	5749.0
SEC13	5748.0
PDE4C	5741.0
GDI1	5739.0
PSENEN	5735.0
CDC42EP2	5731.0
ATP6V1E2	5730.0
MAF1	5723.0
PTPN1	5722.0
WIPF2	5713.0
PF4	5707.0
ATF1	5706.0
LPAR1	5694.0
TAB1	5681.0
GAB1	5679.0
SOX6	5665.0
DVL3	5656.0
AGO1	5654.0
FADD	5641.0
PLXNB1	5639.0
YWHAZ	5624.0
ARHGAP23	5618.0
ECT2	5570.0
KLC1	5523.0
ARHGAP31	5501.0
HDAC2	5482.0
PRKAG1	5476.0
PAFAH1B1	5470.0
USP9X	5464.0
OR2B11	5463.0
FOS	5460.0
PFN1	5459.0
CBX8	5448.0
GTF2F2	5434.0
OR2T33	5429.0
TAOK1	5420.0
CXCL2	5412.0
NSL1	5408.0
MAML1	5404.0
SDC2	5397.0
H2BC9	5394.0
BRAP	5387.0
IKBKG	5377.0
NRAS	5363.0
PSMA2	5339.0
S1PR3	5323.0
PTPN11	5314.0
H2BC15	5312.0
POLR2L	5305.0
STAG2	5301.0
PDGFA	5293.0
NOTCH2	5272.0
ADCY4	5270.0
PAG1	5268.0
PDE6D	5250.0
CALCRL	5232.0
CSK	5219.0
SNW1	5201.0
HNRNPM	5195.0
RAC2	5163.0
TGFB1	5153.0
TBXA2R	5148.0
GPR37L1	5140.0
COL9A3	5126.0
PBX1	5098.0
MYL12B	5088.0
CPT1A	5077.0
KDM1B	5073.0
MAPKAP1	5057.0
COL6A3	5053.0
ARHGAP30	5039.0
ARHGAP21	5032.0
CDC73	5020.0
HBEGF	5013.0
PIK3R2	5010.0
PLCG2	5006.0
H2AC20	4972.0
CDC25C	4969.0
RRAGC	4954.0
GTF2F1	4951.0
CHN2	4938.0
NCK2	4934.0
ID1	4927.0
SMAD2	4905.0
VAV3	4894.0
WNT6	4864.0
PCSK5	4863.0
CXCL3	4851.0
SOX4	4850.0
AR	4840.0
USF1	4829.0
P2RY12	4821.0
EIF4E	4813.0
CNR1	4795.0
F2RL3	4773.0
HDAC11	4756.0
SMARCA4	4733.0
HDAC5	4710.0
NOTCH1	4704.0
PPID	4695.0
BIRC2	4692.0
GRAP2	4690.0
LIMK1	4679.0
HDAC3	4673.0
PLCB2	4665.0
GPSM2	4658.0
RGS10	4637.0
PIK3CA	4629.0
IFT122	4625.0
PSMD3	4618.0
ARHGAP1	4613.0
NRIP1	4609.0
POLR2F	4604.0
SGK1	4595.0
PPP2R1A	4589.0
FGD2	4576.0
LRP8	4568.0
TBL1XR1	4556.0
CAV2	4516.0
HGS	4513.0
CDKN1A	4511.0
GAS8	4496.0
FZD1	4492.0
NCOA1	4483.0
HCAR2	4477.0
PTK2	4462.0
LAMTOR4	4441.0
UBC	4439.0
AATF	4427.0
S1PR4	4425.0
OR6C75	4424.0
ELMO2	4397.0
DIAPH3	4379.0
KCTD6	4371.0
PTGER3	4360.0
DUSP6	4357.0
SEM1	4348.0
NMT1	4328.0
MDM2	4312.0
GNG8	4296.0
B4GALT1	4292.0
LRP5	4289.0
SKP1	4287.0
PDHX	4282.0
DYNC1LI2	4273.0
PDK1	4249.0
PDHB	4233.0
GPR65	4232.0
DYNC1I1	4187.0
SHC2	4183.0
ITGA2	4168.0
KSR1	4167.0
CRHBP	4166.0
CENPA	4162.0
SHC1	4161.0
FMNL1	4150.0
TJP2	4142.0
EPS15	4138.0
APH1A	4133.0
PTGES3	4125.0
CDC37	4096.0
PSMB2	4084.0
SQSTM1	4081.0
CTBP2	4080.0
PPP1CA	4069.0
GOLGA7	4055.0
MAPKAPK2	4054.0
RCVRN	4036.0
CBX6	4033.0
SCD	4026.0
IL6ST	4025.0
CDC20	3998.0
SHC3	3974.0
CSNK2B	3969.0
CRKL	3966.0
C5	3954.0
SOCS1	3947.0
MAP2K5	3940.0
RBX1	3934.0
ATP6V1G1	3931.0
HNRNPF	3929.0
FGF2	3920.0
MMP7	3918.0
TGFBR2	3914.0
STARD8	3913.0
SH2B3	3910.0
CXCL5	3899.0
MAPK13	3865.0
MAPK11	3826.0
ANOS1	3822.0
GGA3	3816.0
DHRS4	3786.0
OR2V2	3755.0
NRG1	3750.0
BIRC5	3738.0
ZRANB1	3730.0
JUN	3722.0
WDR83	3718.0
FAS	3712.0
KRAS	3702.0
STRN	3695.0
PHLPP1	3658.0
EPS15L1	3655.0
HSD17B1	3654.0
AKT1	3614.0
CGN	3591.0
DNM1	3587.0
NPFFR1	3564.0
NCOA3	3522.0
RNF2	3513.0
POLR2G	3508.0
DAAM1	3466.0
OR10G3	3447.0
RGR	3440.0
BMPR2	3427.0
PSMD5	3426.0
CREBBP	3423.0
PIP5K1C	3419.0
OR2C3	3415.0
FFAR4	3410.0
FGD3	3408.0
NLK	3405.0
RLBP1	3401.0
DNAL4	3398.0
AKAP13	3393.0
PSMB1	3374.0
IQGAP3	3370.0
GNA12	3367.0
PMF1	3364.0
KTN1	3363.0
BUB1	3362.0
KIF14	3352.0
PDE11A	3331.0
GNAI1	3329.0
ADORA2A	3293.0
OR8A1	3283.0
GNA11	3259.0
PDK3	3252.0
APC	3240.0
ZNF217	3232.0
INHBA	3227.0
RAP1B	3206.0
KMT2D	3203.0
IL1RL1	3175.0
ARHGEF12	3166.0
TAB3	3160.0
VPS29	3151.0
RAB4B	3137.0
RGS17	3134.0
EGR1	3124.0
DLGAP5	3106.0
NUP98	3101.0
YBX1	3097.0
TNFSF10	3093.0
AVPR1A	3091.0
RPS6KA2	3087.0
HDAC8	3079.0
STARD13	3078.0
GATAD2A	3075.0
NUP37	3074.0
NTRK3	3068.0
ABCG8	3056.0
DERL2	3041.0
NF1	3036.0
KLK2	3029.0
CETP	3003.0
PLK1	3002.0
BUB1B	2997.0
AGO2	2995.0
GLI1	2991.0
RPS6KA3	2973.0
PSPN	2969.0
MTMR4	2951.0
GNAZ	2909.0
LGR4	2883.0
CCNK	2877.0
KHDRBS1	2861.0
POMC	2855.0
RAMP3	2854.0
RACGAP1	2848.0
ARHGAP28	2835.0
OR7D4	2812.0
SLC38A9	2807.0
OR2G6	2743.0
CENPF	2723.0
GTF2A1	2713.0
RALA	2710.0
JAK2	2691.0
EPGN	2662.0
SKA1	2649.0
ARAF	2644.0
ARHGAP32	2642.0
HPN	2625.0
PSMD14	2611.0
SDC3	2599.0
PSMC2	2598.0
NDE1	2594.0
ANGPT1	2562.0
RANBP10	2553.0
LPL	2545.0
PLPPR3	2540.0
PSMB4	2523.0
PTPRO	2501.0
SMPD2	2476.0
OR52A1	2461.0
ARHGEF6	2453.0
OR51L1	2440.0
PPP2R5D	2421.0
CFTR	2416.0
OR2H2	2406.0
MAP3K7	2395.0
GREM2	2392.0
GRPR	2385.0
OR7C1	2378.0
OR2M4	2367.0
TRIP10	2343.0
STRADA	2330.0
SPC24	2306.0
MYC	2304.0
SPRY1	2302.0
STK11	2289.0
PRICKLE1	2283.0
HDAC10	2280.0
ADRA2A	2271.0
SFPQ	2253.0
CBX4	2222.0
RBCK1	2214.0
OPRM1	2161.0
CCR9	2157.0
GRK4	2147.0
MT-RNR2	2112.0
RASA1	2106.0
ATF2	2085.0
CBFB	2078.0
POFUT1	2056.0
TSHR	2051.0
MCF2	2018.0
PRKAG2	2015.0
ARRB1	1998.0
WNT9B	1992.0
PSMC3	1976.0
CAV1	1969.0
HCAR3	1965.0
CAMK2G	1921.0
EREG	1888.0
CCNC	1877.0
HSPB1	1863.0
ACKR2	1860.0
PIK3CG	1833.0
CNGB1	1822.0
TRIO	1820.0
TNFRSF10A	1815.0
GALNT3	1805.0
PPP1R12B	1775.0
DEPDC1B	1774.0
FER	1761.0
OR2M3	1744.0
IRS1	1741.0
CXCL8	1729.0
RAD21	1709.0
MMP9	1690.0
MECOM	1687.0
CDC14B	1678.0
OR5AU1	1664.0
ARHGAP11A	1642.0
PIK3C3	1619.0
POLR2C	1616.0
SFN	1615.0
RGS3	1612.0
NPHP4	1607.0
ARHGAP22	1595.0
TGFBR1	1585.0
PSMD10	1559.0
JUND	1549.0
CDK1	1540.0
POU2F1	1537.0
PTGER2	1463.0
QRFP	1452.0
OR1D2	1418.0
XIAP	1407.0
ARF6	1377.0
FOSB	1368.0
TACR2	1363.0
HDAC9	1359.0
NAB1	1342.0
TERT	1341.0
HSP90AA1	1326.0
PRKAA1	1322.0
ITCH	1318.0
KAT5	1314.0
BRAF	1308.0
LRP2	1307.0
PRKAB1	1302.0
STAM	1285.0
VRK3	1281.0
SSTR2	1275.0
RHOB	1254.0
DACT1	1252.0
EIF4B	1247.0
OR14L1P	1243.0
PDE4D	1217.0
OR56A1	1212.0
ARHGAP4	1204.0
PLCB1	1197.0
WWC1	1180.0
SPOP	1151.0
OR1I1	1136.0
PRKCA	1132.0
UBA52	1121.0
TF	1102.0
NCOA2	1092.0
ELK1	1040.0
RBBP5	1037.0
RIPK2	1025.0
SAG	998.0
GABRG2	996.0
SYVN1	992.0
PRC1	980.0
COL4A2	970.0
GNG3	890.0
CSNK1G2	887.0
GNAT1	877.0
REST	865.0
MST1	849.0
AURKB	846.0
CUL5	834.0
FKBP4	832.0
ELF3	828.0
FUZ	803.0
EVC	780.0
KIF2C	726.0
DEPDC7	725.0
RPS6KB2	700.0
ERLEC1	698.0
SAV1	679.0
MYH10	653.0
TIAM1	651.0
SMC1A	613.0
CHD8	604.0
RDH5	591.0
HDAC1	587.0
LRP6	577.0
WIPF1	569.0
CAMKMT	550.0
YY1	537.0
GNB5	512.0
NR3C1	511.0
ST3GAL3	505.0
LAMB2	501.0
RETSAT	498.0
FLNA	483.0
AKR1C1	473.0
IL33	445.0
TAS2R14	440.0
AKT2	433.0
APOM	429.0
ADGRE3	408.0
POLR2I	396.0
LTB4R2	384.0
MLST8	376.0
NELFB	374.0
CENPE	332.0
NCKIPSD	328.0
KREMEN2	316.0
MYB	302.0
WASL	299.0
AVPR2	291.0
TCF7L1	275.0
ARHGAP15	272.0
ATN1	234.0
ABL1	226.0
APOE	218.0
ADCY9	123.0
GALR1	122.0
RACK1	119.0
KISS1R	107.0
TNS4	100.0
PKN2	98.0
RASAL2	79.0
CHD1	69.0
EGR3	44.0
LEO1	39.0
ZW10	31.0
CENPN	20.0
DVL1	0.0
CD86	-14.0
KDM4A	-20.0
FRK	-24.0
ABHD17B	-35.0
CXCR4	-45.0
HCAR1	-49.0
WNT5B	-61.0
PTPN3	-85.0
ITGB1	-94.0
PRKCI	-138.0
OR10AC1	-155.0
PTBP1	-205.0
BAIAP2	-215.0
STK4	-220.0
TRAF6	-229.0
PARD6A	-239.0
PPP2R1B	-241.0
OR2AT4	-242.0
MEF2C	-293.0
OR4K17	-339.0
METAP2	-343.0
ERCC6L	-415.0
APOD	-426.0
ACTA2	-429.0
GPR132	-446.0
ERBB3	-472.0
ARHGAP44	-483.0
TNKS2	-499.0
DGKD	-501.0
CAB39L	-519.0
MBD3	-528.0
TRADD	-556.0
ARL2	-565.0
ERBIN	-574.0
KNL1	-581.0
MAML2	-582.0
CLASP1	-588.0
PSMA4	-616.0
CASP3	-632.0
OR4D9	-638.0
GPNMB	-672.0
PPP2R5E	-680.0
OTULIN	-683.0
FASN	-690.0
NBEA	-703.0
NUDC	-709.0
RRAGB	-713.0
SKIL	-725.0
GPR83	-743.0
XCR1	-749.0
ICMT	-786.0
OXTR	-791.0
TSC2	-804.0
PDE2A	-808.0
CCR10	-810.0
RANBP2	-820.0
SYDE2	-845.0
DIAPH1	-854.0
PSMC5	-863.0
CORT	-886.0
GPS2	-889.0
ATP2A3	-914.0
GRK5	-919.0
USP34	-944.0
OR7G2	-970.0
AGO3	-1011.0
STUB1	-1032.0
LAMA1	-1044.0
RASAL1	-1060.0
PPEF1	-1061.0
KIF2A	-1069.0
MAPK12	-1074.0
CDK5R1	-1089.0
OPHN1	-1158.0
NMB	-1160.0
XPO1	-1185.0
PDE6G	-1189.0
BCL9	-1190.0
REEP1	-1191.0
H2AZ2	-1209.0
TAS1R3	-1224.0
GRM6	-1228.0
TCF12	-1233.0
PLAT	-1242.0
OR5A1	-1282.0
NSMAF	-1303.0
MAPK7	-1337.0
CREB1	-1378.0
OR10A6	-1385.0
EGR2	-1435.0
CRABP2	-1447.0
OR7D2	-1582.0
SEPTIN7	-1594.0
IFT52	-1596.0
COL6A1	-1605.0
ADCY6	-1608.0
AHCTF1	-1644.0
DUSP10	-1650.0
SRMS	-1710.0
PCP2	-1714.0
GATAD2B	-1759.0
POLR2K	-1783.0
RELA	-1803.0
IFT57	-1811.0
LATS1	-1825.0
CDCA8	-1838.0
PDE7B	-1841.0
RBBP4	-1870.0
NRG4	-1875.0
TRPC6	-1935.0
ZNRF3	-1963.0
LRRC7	-1966.0
CDK8	-1971.0
SMC3	-1975.0
PLG	-1977.0
GABRB3	-1992.0
LAMC3	-2016.0
ABHD17C	-2037.0
NOS3	-2059.0
CALM1	-2081.0
TSC1	-2118.0
OR10H5	-2146.0
CLASP2	-2151.0
GNG4	-2154.0
IFT88	-2201.0
PDE6A	-2204.0
PKN1	-2208.0
ATP6V1C2	-2219.0
LAMA4	-2252.0
OR7A5	-2276.0
TIAL1	-2282.0
F2RL2	-2284.0
PIK3R5	-2304.0
PFN2	-2339.0
GABBR1	-2363.0
PIP4K2A	-2365.0
DOCK7	-2369.0
ROR1	-2376.0
GNB3	-2397.0
SUZ12	-2409.0
KAT2B	-2414.0
HTR7	-2438.0
CASP2	-2471.0
CHEK1	-2481.0
POLR2B	-2523.0
ADGRE5	-2571.0
NEURL1B	-2586.0
SMURF1	-2591.0
SOX7	-2675.0
AP2B1	-2709.0
OR1C1	-2716.0
PTPRU	-2724.0
KIF18A	-2742.0
OR1M1	-2746.0
RXFP4	-2801.0
ABHD6	-2829.0
WNT8B	-2841.0
SCRIB	-2849.0
OR4E1	-2862.0
ADCY2	-2896.0
RAPGEF3	-2911.0
OR6Y1	-2926.0
POLR2H	-2942.0
PHB	-2995.0
MIB1	-2998.0
MTA1	-3005.0
CCL3	-3027.0
NUP85	-3049.0
PSMB8	-3076.0
POLR2A	-3092.0
MEF2D	-3094.0
CENPI	-3162.0
DGKH	-3178.0
PIN1	-3188.0
DUSP7	-3211.0
OR7A17	-3221.0
RAC3	-3262.0
LAMA5	-3263.0
OR1A1	-3272.0
RXRB	-3276.0
ADCY7	-3286.0
FGFR4	-3293.0
NGFR	-3331.0
DTX1	-3340.0
ARHGAP35	-3359.0
KSR2	-3361.0
HRAS	-3382.0
ETV4	-3386.0
FRS2	-3433.0
CASP10	-3446.0
SGO2	-3480.0
RPS6KB1	-3493.0
PDE4A	-3520.0
MYH11	-3522.0
DLAT	-3526.0
SPTBN5	-3531.0
OR2A5	-3544.0
LPAR6	-3569.0
UTS2	-3581.0
NR1H3	-3597.0
AAMP	-3636.0
FLRT2	-3656.0
KALRN	-3692.0
MDK	-3714.0
LIN7B	-3725.0
COL4A4	-3759.0
TAS2R30	-3784.0
PLIN1	-3785.0
PKN3	-3793.0
DAB2IP	-3826.0
TCF4	-3836.0
CD19	-3843.0
ARHGEF4	-3861.0
PAQR3	-3864.0
UHMK1	-3877.0
COL4A3	-3896.0
LINC01139	-3904.0
ARHGEF38	-3906.0
CDK9	-3927.0
WNT2B	-3938.0
OR6K3	-3942.0
PMEPA1	-3963.0
KANK1	-3964.0
ARHGEF26	-3971.0
DYNLL2	-3980.0
MYLIP	-3991.0
ARHGEF10	-4015.0
POLR2D	-4024.0
MED1	-4036.0
VAV2	-4055.0
INTU	-4059.0
PIK3R4	-4062.0
RING1	-4063.0
OR5AN1	-4095.0
RASGRF1	-4123.0
PAK3	-4184.0
FCER2	-4230.0
FGF7	-4247.0
UCN	-4278.0
GPC2	-4280.0
NRP2	-4282.0
NUF2	-4301.0
RASA2	-4320.0
TAS2R20	-4326.0
AMH	-4383.0
WNT9A	-4397.0
IFT140	-4423.0
FMNL2	-4424.0
HTR6	-4426.0
WNT4	-4485.0
CHD4	-4515.0
TNRC6B	-4518.0
ARHGEF35	-4533.0
PDHA1	-4581.0
ARHGEF7	-4583.0
CPT1B	-4584.0
MCHR1	-4598.0
SPRY2	-4603.0
CBX2	-4617.0
PTPRA	-4626.0
GPC1	-4627.0
DOCK3	-4640.0
RHPN2	-4650.0
SMAD5	-4651.0
RDH10	-4665.0
ATP2A1	-4667.0
RCE1	-4674.0
WNT3	-4684.0
SPPL2B	-4688.0
BCL2	-4704.0
PTCH2	-4708.0
OR14J1	-4716.0
GPC4	-4730.0
ZWINT	-4742.0
ADAM12	-4744.0
TAS2R3	-4767.0
CNKSR2	-4781.0
OPRD1	-4782.0
PNOC	-4890.0
GUCA1B	-4897.0
WNT16	-4921.0
BTRC	-4924.0
HRH1	-4934.0
MAD1L1	-4981.0
CDK2	-5006.0
RGS5	-5029.0
SMAD9	-5040.0
CIT	-5064.0
CRHR2	-5119.0
SPTBN2	-5129.0
CENPO	-5135.0
RCC2	-5148.0
RARG	-5153.0
GNG7	-5198.0
CCNT2	-5205.0
NOTCH4	-5229.0
KHDRBS2	-5270.0
PTENP1	-5280.0
PSMA3	-5285.0
REEP2	-5289.0
RGS1	-5296.0
RHPN1	-5327.0
TIA1	-5344.0
FGFR1	-5352.0
JUP	-5353.0
CENPM	-5376.0
IKBKB	-5386.0
EFCAB7	-5419.0
NEFL	-5425.0
S100B	-5457.0
NOXA1	-5464.0
ARHGAP33	-5517.0
GPR161	-5538.0
RHOT2	-5546.0
RHOBTB2	-5551.0
ARHGEF1	-5559.0
MAMLD1	-5584.0
TNRC6A	-5613.0
MST1R	-5615.0
DNAJB1	-5672.0
SRGAP3	-5675.0
DGKZ	-5681.0
SOS1	-5700.0
SCUBE2	-5701.0
RASGEF1A	-5704.0
DLG2	-5717.0
FNTA	-5724.0
PSMB10	-5735.0
GPSM1	-5766.0
STAP2	-5775.0
PGF	-5814.0
SCMH1	-5839.0
TRIB3	-5843.0
NCBP1	-5853.0
HRH4	-5875.0
HNRNPA1	-5924.0
TAS2R5	-5926.0
INCENP	-5956.0
MUC20	-5962.0
TLR9	-5999.0
MFNG	-6008.0
EVC2	-6012.0
OR5A2	-6014.0
SORCS3	-6044.0
PSMA5	-6053.0
SEH1L	-6069.0
PSME4	-6087.0
SALL4	-6112.0
WWTR1	-6131.0
VIPR1	-6156.0
RPS6	-6160.0
UTS2B	-6163.0
MRAS	-6172.0
TCF7L2	-6185.0
CKAP5	-6246.0
LPAR3	-6276.0
DUSP4	-6287.0
ARHGEF10L	-6295.0
STAG1	-6347.0
CENPQ	-6366.0
FOXO6	-6367.0
TJP1	-6374.0
PPARD	-6394.0
CHRM5	-6404.0
ZDHHC21	-6453.0
CTBP1	-6456.0
RRH	-6491.0
FZD7	-6508.0
FZD6	-6525.0
NF2	-6540.0
H2BU1	-6555.0
FBXW7	-6600.0
FGF23	-6622.0
GPR15	-6636.0
OR2A7	-6650.0
DUSP16	-6655.0
CENPU	-6692.0
OR2A1	-6705.0
SGO1	-6715.0
TRRAP	-6722.0
OBSCN	-6727.0
USP13	-6737.0
NR4A1	-6756.0
CASR	-6767.0
GRK7	-6773.0
OR5AS1	-6779.0
ARHGEF18	-6799.0
PEA15	-6825.0
SPRED3	-6835.0
CD80	-6841.0
PDE8B	-6846.0
HSP90AB1	-6863.0
KPNA2	-6910.0
GREB1	-6937.0
RPS27A	-6938.0
TLE1	-6942.0
ARHGEF5	-6944.0
PDE8A	-6957.0
CCND1	-6970.0
USP21	-6972.0
INPP5B	-7024.0
CXXC5	-7037.0
DRAP1	-7046.0
BCR	-7071.0
CNKSR1	-7089.0
GNAL	-7090.0
ALDH8A1	-7123.0
ACKR4	-7128.0
TAS2R4	-7129.0
GPBAR1	-7132.0
FZD8	-7138.0
DISP2	-7144.0
IL2RA	-7161.0
NAPEPLD	-7168.0
FZD3	-7186.0
FLT4	-7216.0
ACVR1C	-7219.0
PTPRK	-7262.0
RBFOX2	-7280.0
TNF	-7308.0
MTA2	-7317.0
YWHAQ	-7340.0
RTP5	-7388.0
NET1	-7419.0
PDE4B	-7429.0
TLE2	-7449.0
PPP5C	-7462.0
WDR19	-7511.0
TRAT1	-7535.0
ARHGAP12	-7547.0
PSMA8	-7606.0
ARHGAP42	-7608.0
ITGB3BP	-7621.0
ITPR1	-7629.0
CCR8	-7641.0
CCR7	-7649.0
EDN3	-7653.0
CNR2	-7662.0
ADRB1	-7674.0
CYSLTR1	-7675.0
DYNC1H1	-7685.0
GHSR	-7695.0
IKZF1	-7704.0
PSEN2	-7718.0
NUP133	-7762.0
SPTBN1	-7764.0
HSPG2	-7779.0
PIP4K2B	-7788.0
ARHGAP11B	-7789.0
GNG2	-7795.0
CHN1	-7833.0
ZFYVE9	-7848.0
RET	-7856.0
UCHL5	-7861.0
CCR6	-7862.0
SCAI	-7879.0
ARHGAP17	-7888.0
KNTC1	-7897.0
GLI3	-7910.0
VEGFB	-7929.0
HNRNPH1	-7932.0
MAD2L1	-7944.0
DYNC2H1	-7947.0
ABCG1	-7961.0
WNT7A	-7966.0
DGKA	-7980.0
PRKCE	-8001.0
RAMP1	-8039.0
PDK2	-8047.0
LEF1	-8076.0
CXXC4	-8078.0
OR2I1P	-8104.0
DGKQ	-8149.0
PHC3	-8152.0
AXIN2	-8154.0
CXCL10	-8160.0
ARHGAP39	-8166.0
PRKAB2	-8172.0
CDON	-8176.0
NTRK1	-8193.0
CDKN1B	-8207.0
ADCY5	-8235.0
HES1	-8266.0
METAP1	-8295.0
CENPK	-8334.0
BMPR1A	-8335.0
DLG1	-8336.0
HDAC6	-8337.0
SMAD4	-8351.0
MAPKAPK5	-8364.0
LFNG	-8372.0
KLC4	-8376.0
THBS4	-8396.0
PHC1	-8402.0
CTNND1	-8403.0
ARHGAP25	-8441.0
PRKG2	-8477.0
GNRH1	-8483.0
RASGRP2	-8529.0
MEN1	-8538.0
E2F5	-8568.0
MCF2L	-8571.0
PDGFB	-8577.0
DAGLA	-8578.0
GNRHR2	-8582.0
RDH16	-8604.0
FGF22	-8607.0
RUVBL1	-8612.0
CENPH	-8633.0
RLN2	-8636.0
SPRED1	-8639.0
TPH1	-8640.0
STMN1	-8663.0
SH2B1	-8670.0
TGIF1	-8682.0
GFRA2	-8689.0
ESRP2	-8691.0
PML	-8693.0
NRP1	-8717.0
TNKS	-8738.0
BCO2	-8744.0
PLEKHG5	-8758.0
FGF9	-8761.0
ARHGEF19	-8776.0
SRC	-8820.0
TRIM33	-8823.0
GPR55	-8827.0
ARHGAP10	-8847.0
CCR5	-8861.0
KIF5A	-8869.0
CILP	-8873.0
ARHGAP5	-8885.0
ADORA1	-8946.0
GUCY2D	-8954.0
CYSLTR2	-8970.0
SKA2	-8999.0
WNT1	-9014.0
KLC2	-9059.0
POGLUT1	-9094.0
ESR1	-9122.0
PTGIR	-9126.0
PSMC4	-9127.0
SYNGAP1	-9140.0
NFATC1	-9147.0
NDC80	-9165.0
TBP	-9167.0
S1PR1	-9211.0
PRMT1	-9229.0
EDN1	-9248.0
ESR2	-9250.0
XCL1	-9270.0
FGFBP3	-9275.0
CYP4V2	-9298.0
HHAT	-9301.0
TRPC3	-9343.0
RYK	-9346.0
EED	-9348.0
CYLD	-9359.0
DUSP2	-9373.0
GAS1	-9378.0
RASGRP3	-9414.0
MAPK8	-9428.0
KDM1A	-9430.0
MTA3	-9433.0
ICOS	-9434.0
GHRL	-9461.0
FOXO1	-9465.0
CCNT1	-9469.0
PIK3R1	-9505.0
ATP6V1G2	-9515.0
NUP43	-9517.0
NCBP2	-9558.0
MYO9A	-9588.0
CENPT	-9606.0
ID3	-9614.0
RGS9	-9636.0
OR52N4	-9656.0
RICTOR	-9670.0
OR4D1	-9690.0
CXCR5	-9727.0
CHD3	-9737.0
EZH2	-9741.0
F2R	-9750.0
HEY2	-9752.0
RPS27	-9756.0
MTOR	-9767.0
COL9A2	-9770.0
ACKR3	-9771.0
NOG	-9796.0
RAPGEF1	-9826.0
BMI1	-9829.0
GOPC	-9831.0
DDX5	-9843.0
WNT10A	-9848.0
A2M	-9870.0
FLT3LG	-9894.0
CCR4	-9900.0
LAMA2	-9911.0
WNT10B	-9917.0
GNAO1	-9936.0
GPR150	-9942.0
CLIP3	-9943.0
CAMK4	-9956.0
RBL1	-9959.0
PSME1	-9991.0
SSTR3	-10021.0
PORCN	-10074.0
CBY1	-10077.0
TGIF2	-10105.0
WWP1	-10106.0
CDC14A	-10119.0
PRDM4	-10148.0
TCF7	-10173.0
RASGRF2	-10175.0
EBAG9	-10187.0
RNF31	-10192.0
REEP6	-10201.0
CD28	-10202.0
COL6A2	-10206.0
GPAM	-10241.0
AXIN1	-10285.0
CSNK1E	-10298.0
RPGRIP1L	-10301.0
ITPR3	-10308.0
DGKK	-10314.0
GRAP	-10321.0
PSME2	-10336.0
SMURF2	-10340.0
MIR25	-10350.0
CYFIP2	-10367.0
LRIG1	-10389.0
RDH14	-10397.0
NAB2	-10400.0
ABHD12	-10401.0
NUP107	-10421.0
PRKX	-10428.0
WDR35	-10457.0
RPTOR	-10464.0
FAM13B	-10519.0
NUP160	-10557.0
ACVR2B	-10569.0
CXCL9	-10574.0
RDH13	-10602.0
CX3CR1	-10624.0
RHOH	-10626.0
MKS1	-10634.0
ABHD17A	-10672.0
GPR25	-10677.0
IFT172	-10736.0
KDM4C	-10749.0
ITGA3	-10750.0
OTUD3	-10763.0
KAT2A	-10771.0
DSN1	-10773.0
DRD4	-10808.0
ARHGEF39	-10833.0
XCL2	-10854.0
PTPN7	-10868.0
PDE7A	-10882.0
TP53	-10893.0
MIS12	-10903.0
P2RY11	-10907.0
ABI2	-10915.0
PELP1	-10928.0
TNFAIP3	-10950.0
JAK1	-10955.0
P2RY6	-10964.0
ID2	-10969.0
TIAM2	-10979.0
CCL5	-10985.0
KIT	-11004.0
JAG2	-11044.0
SLC24A1	-11057.0
THEM4	-11069.0
MIB2	-11073.0
RIPK1	-11074.0
WWOX	-11085.0
CCL28	-11088.0
EEF2K	-11089.0
CCR3	-11109.0
LPAR5	-11110.0
SKI	-11113.0
PLCG1	-11120.0
BIRC3	-11125.0
DVL2	-11152.0
RGS12	-11170.0
TTC21B	-11179.0
CXCR6	-11180.0
MC1R	-11184.0
RASA4	-11206.0
IL5RA	-11211.0
CNOT6L	-11248.0
CDK4	-11256.0
PPP2R5C	-11265.0
PEBP1	-11270.0
GRM2	-11275.0
SOX13	-11280.0
MXD4	-11285.0
OFD1	-11296.0
AMER1	-11301.0
PDE3B	-11322.0
PSMB9	-11324.0
PYGO2	-11326.0
CUL1	-11330.0
CASP8	-11336.0
ACVR2A	-11338.0
RHOC	-11360.0
PIP4K2C	-11371.0
PDE6B	-11387.0
DGKE	-11390.0
SPTAN1	-11426.0
RAG1	-11432.0
NCK1	-11454.0
RTP4	-11457.0
CDH1	-11500.0
S1PR2	-11503.0
KIF7	-11533.0
SPDL1	-11534.0
PDGFRB	-11545.0
ATP6V0E2	-11555.0
CMKLR1	-11560.0
RPS6KA5	-11594.0
CXCR3	-11603.0
PRKCZ	-11629.0
NEURL1	-11633.0
DUSP8	-11639.0
FZD4	-11650.0
FYN	-11675.0
LAT	-11694.0
GPR20	-11696.0
PTGER4	-11697.0
NCAM1	-11706.0
CCNE1	-11707.0
BUB3	-11709.0
RANGAP1	-11722.0
ZWILCH	-11724.0
STAT1	-11727.0
SMAD3	-11745.0
TRAF2	-11746.0
PARP1	-11764.0
ALDH1A1	-11765.0
AGRN	-11770.0
FGFRL1	-11778.0
CENPL	-11782.0
FGFR2	-11785.0
GPR183	-11803.0
CENPP	-11814.0
CAMK2D	-11816.0
RASA3	-11820.0
TNRC6C	-11828.0
TULP3	-11833.0
LCK	-11838.0
AKT3	-11849.0
SMAD7	-11872.0
DLL1	-11885.0
SCT	-11886.0
GPR18	-11887.0
CENPC	-11888.0
ADRB2	-11892.0
MADD	-11899.0
DLG3	-11922.0
P2RY10	-11926.0
PTCH1	-11936.0
P2RY14	-11940.0
TRAF1	-11947.0
PHLPP2	-11948.0
TLE5	-11957.0
PRKACB	-11959.0
KIF3A	-11972.0
RASGRP1	-11974.0
CCL4	-11976.0
BCL9L	-11981.0
ARAP2	-11984.0
PRR5	-11985.0
MOV10	-11991.0
RASAL3	-12014.0
PIK3R3	-12015.0
PTGDR	-12021.0
ARHGEF3	-12022.0
NMT2	-12035.0
CCDC88C	-12041.0
IL2RG	-12050.0
IL3RA	-12057.0
DHRS3	-12084.0
GNGT2	-12086.0
FMNL3	-12087.0
OTUD7B	-12095.0
GIPR	-12100.0
KDM3A	-12102.0
AKR1C3	-12104.0
FPR3	-12116.0
RNF43	-12121.0
PPP3CC	-12126.0
PRKCQ	-12127.0
PTGDR2	-12132.0
RALGDS	-12140.0
YES1	-12142.0
VIPR2	-12153.0
GPR68	-12154.0
RBBP7	-12155.0
GATA3	-12191.0
EVL	-12207.0
ATP6V0A2	-12211.0
ARHGEF25	-12219.0
AMOT	-12223.0
NMUR1	-12226.0
DUSP5	-12227.0
SMPD3	-12234.0
FGFBP2	-12244.0
PDGFD	-12247.0
RTKN	-12249.0
MATK	-12255.0
C3	-12262.0
ARHGAP8	-12284.0
TAGAP	-12285.0
LGR6	-12286.0
PTPRS	-12291.0
MAGED1	-12295.0
ARL4C	-12296.0
ARHGEF9	-12299.0
S1PR5	-12315.0
ERBB2	-12320.0
PRKCH	-12324.0
AXL	-12331.0
CCL2	-12341.0
RHOF	-12344.0
IL2RB	-12347.0
RUNX3	-12352.0
SH2D2A	-12359.0
GZMB	-12361.0
TFDP2	-12364.0
FASLG	-12371.0

---

Hemostasis

Hemostasis

	497
set	Hemostasis
setSize	549
pANOVA	9.7e-23
s.dist	0.245
p.adjustANOVA	1.89e-20

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SIRPA	9510
F12	9492
F5	9485
CYB5R1	9460
GNA15	9452
CD36	9444
SERPINB2	9438
NFE2	9431
PRKACA	9429
MAFG	9407
ITGAM	9398
CLU	9371
GNG10	9349
APLP2	9347
GRB2	9304
QSOX1	9298
CD63	9287
HBE1	9275
ALDOA	9249
LHFPL2	9224

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SIRPA	9510.0
F12	9492.0
F5	9485.0
CYB5R1	9460.0
GNA15	9452.0
CD36	9444.0
SERPINB2	9438.0
NFE2	9431.0
PRKACA	9429.0
MAFG	9407.0
ITGAM	9398.0
CLU	9371.0
GNG10	9349.0
APLP2	9347.0
GRB2	9304.0
QSOX1	9298.0
CD63	9287.0
HBE1	9275.0
ALDOA	9249.0
LHFPL2	9224.0
FERMT3	9223.0
PHF21A	9216.0
SERPINB8	9205.0
PLA2G4A	9180.0
APP	9177.0
BSG	9172.0
SERPINA1	9168.0
MAPK14	9104.0
HBD	9100.0
ACTN1	9094.0
THBD	9082.0
SYK	9076.0
RCOR1	9073.0
TNFRSF10D	9072.0
HBB	9054.0
PIK3CB	9038.0
STXBP2	9035.0
PRKCD	9008.0
GNAQ	8993.0
MAPK3	8953.0
ITGB2	8942.0
CLEC1B	8931.0
SELL	8912.0
CRK	8906.0
ITGA2B	8893.0
F13A1	8876.0
HGF	8863.0
TOR4A	8861.0
VTI1B	8850.0
GNG5	8815.0
RAC1	8793.0
LAMP2	8786.0
SLC16A3	8783.0
SRGN	8761.0
APBB1IP	8744.0
ITGA1	8729.0
HBG2	8722.0
TIMP1	8677.0
H3-3A	8661.0
CDK5	8616.0
PRKAR1A	8607.0
CAPZA2	8597.0
ANXA2	8544.0
TLN1	8525.0
ARRB2	8490.0
RHOG	8487.0
CLEC3B	8480.0
FGR	8478.0
SELP	8457.0
SLC8A1	8444.0
P2RX1	8436.0
CEACAM1	8429.0
PLAUR	8424.0
GATA1	8410.0
CD44	8333.0
CD99	8326.0
TNFRSF10B	8321.0
RHOA	8319.0
KIF3C	8306.0
GNB1	8294.0
ITGB3	8291.0
FN1	8284.0
MERTK	8257.0
SYTL4	8256.0
KIF5B	8239.0
PPP2CA	8234.0
PRCP	8218.0
ANXA5	8210.0
CFL1	8186.0
KIF1B	8184.0
EGF	8179.0
HBG1	8157.0
GNB2	8141.0
CAPZA1	8135.0
FCER1G	8131.0
CAP1	8111.0
GYPB	8109.0
JAML	8107.0
GNAI2	8075.0
GAS6	8063.0
F11R	8058.0
ATP2A2	8038.0
LY6G6F	8023.0
CAPZB	8015.0
ORM1	7971.0
DGKG	7958.0
GNAI3	7953.0
PRKAR1B	7918.0
GNAS	7909.0
VAV1	7896.0
CALU	7894.0
RAF1	7879.0
PECAM1	7855.0
P2RY1	7852.0
GYPA	7820.0
LYN	7809.0
KIF1C	7799.0
CD99L2	7793.0
SCCPDH	7787.0
PROS1	7758.0
DOCK2	7725.0
MMRN1	7714.0
PPP2CB	7712.0
MGLL	7694.0
DOCK4	7692.0
ITGA5	7659.0
P2RX4	7630.0
SH2B2	7609.0
CDC42	7537.0
ESAM	7531.0
DOCK5	7524.0
GP9	7506.0
MAPK1	7493.0
SERPINE1	7483.0
GP1BB	7470.0
VEGFA	7467.0
ABCC4	7434.0
STXBP3	7424.0
KLC3	7377.0
TAGLN2	7367.0
AKAP10	7344.0
SPARC	7339.0
ITGAX	7337.0
GNB4	7336.0
VCL	7328.0
DOCK1	7314.0
RAP1A	7305.0
PIK3R6	7270.0
PSAP	7145.0
SLC7A7	7123.0
RAB5A	7103.0
PRKCB	7097.0
HSPA5	7029.0
GYPC	7027.0
F8	7022.0
TREM1	7009.0
WDR1	6976.0
VEGFC	6906.0
PRKG1	6901.0
MMP1	6891.0
S100A10	6860.0
ITPK1	6851.0
CEACAM3	6838.0
KCNMB4	6825.0
GP6	6818.0
KCNMA1	6787.0
PPP2R5B	6774.0
PRTN3	6762.0
MFN2	6750.0
PRKAR2B	6741.0
H3C15	6699.5
PDE5A	6678.0
CD58	6647.0
VWF	6641.0
SDC4	6637.0
SRI	6554.0
GNG11	6495.0
TUBA4A	6484.0
TSPAN7	6469.0
SERPINE2	6451.0
IRF2	6427.0
ATP1B2	6378.0
GTPBP2	6331.0
TMSB4X	6295.0
JAM3	6294.0
GP1BA	6279.0
EHD2	6167.0
PRKAR2A	6166.0
PDPK1	6136.0
ITGAV	6106.0
PTPN6	6096.0
MICAL1	6071.0
PPBP	6042.0
DOCK8	6028.0
ORAI2	6010.0
KIF13B	5998.0
THBS1	5951.0
CD9	5940.0
PPP2R5A	5897.0
PDE1B	5874.0
SERPINB6	5854.0
ITPR2	5842.0
GNA13	5836.0
DAGLB	5820.0
PTPN1	5722.0
PF4	5707.0
YWHAZ	5624.0
A1BG	5559.0
KLC1	5523.0
KIF23	5510.0
HDAC2	5482.0
PFN1	5459.0
PHACTR2	5410.0
SDC2	5397.0
NRAS	5363.0
RAD51B	5318.0
PTPN11	5314.0
PDGFA	5293.0
SLC3A2	5222.0
CSK	5219.0
ECM1	5176.0
RAC2	5163.0
TGFB1	5153.0
TBXA2R	5148.0
KIF20A	5096.0
ACTN4	5049.0
PIK3R2	5010.0
PLCG2	5006.0
CEACAM8	4956.0
OLA1	4914.0
EHD3	4904.0
PLAU	4903.0
VAV3	4894.0
HMG20B	4839.0
P2RY12	4821.0
F2RL3	4773.0
PIK3CA	4629.0
PPP2R1A	4589.0
LRP8	4568.0
CEACAM6	4509.0
PTK2	4462.0
SLC16A1	4455.0
EHD1	4358.0
CD109	4316.0
SELPLG	4301.0
GNG8	4296.0
KIF9	4253.0
ITGA2	4168.0
SHC1	4161.0
STIM1	3938.0
SH2B3	3910.0
DOCK11	3876.0
KIF3B	3740.0
KRAS	3702.0
ALB	3668.0
AKT1	3614.0
PICK1	3594.0
KIF4A	3585.0
P2RX7	3475.0
CD84	3425.0
RAB27B	3386.0
GNA12	3367.0
ENDOD1	3361.0
KCNMB3	3343.0
PDE11A	3331.0
GNAI1	3329.0
TIMP3	3296.0
GNA11	3259.0
RAP1B	3206.0
JMJD1C	3192.0
SLC7A5	3012.0
RACGAP1	2848.0
CHID1	2811.0
KIF16B	2785.0
JAK2	2691.0
MPL	2634.0
SDC3	2599.0
ANGPT1	2562.0
MANF	2550.0
KIF27	2549.0
DOCK6	2531.0
VPS45	2496.0
OLR1	2486.0
CD177	2457.0
PPP2R5D	2421.0
ADRA2A	2271.0
PLEK	1999.0
ARRB1	1998.0
CFD	1984.0
CAV1	1969.0
SLC7A8	1916.0
SLC8A3	1886.0
PIK3CG	1833.0
TNFRSF10A	1815.0
GRB14	1730.0
APOOL	1609.0
SLC16A8	1608.0
CD48	1493.0
NOS1	1365.0
GP5	1295.0
RHOB	1254.0
PF4V1	1211.0
TTN	1195.0
KIF6	1147.0
PRKCA	1132.0
TF	1102.0
MAFK	901.0
GNG3	890.0
KIF11	787.0
KIF2C	726.0
SLC7A9	622.0
STX4	606.0
HDAC1	587.0
GNB5	512.0
FLNA	483.0
MAFF	426.0
IGHV1-2	360.0
CENPE	332.0
MYB	302.0
JAM2	243.0
IGHV2-5	230.0
ABL1	226.0
AK3	164.0
IGHV3-53	103.0
ITGB1	-94.0
KIF18B	-143.0
PPP2R1B	-241.0
KIFC1	-249.0
GLG1	-319.0
ITGA10	-322.0
P2RX5	-435.0
IGHV3-7	-441.0
KCNMB1	-464.0
DGKD	-501.0
IGHV1-46	-618.0
IGHV3-48	-668.0
PPP2R5E	-680.0
TMX3	-775.0
IGKV3-11	-781.0
PDE2A	-808.0
C1QBP	-822.0
ATP2A3	-914.0
DOK2	-952.0
IGKV1-39	-989.0
IGLV7-46	-1016.0
KIF2A	-1069.0
VPREB3	-1146.0
LCP2	-1156.0
IGKV1-5	-1184.0
PLAT	-1242.0
IGHA2	-1274.0
IGLV2-8	-1294.0
IGKV5-2	-1298.0
IGHV3-23	-1317.0
ATP1B3	-1347.0
IGHV3-13	-1443.0
IGLV2-18	-1524.0
IGKV1-16	-1528.0
IGLV4-69	-1559.0
IGKV1D-39	-1574.0
KIFC2	-1642.0
IGHV1-69	-1822.0
IGLV10-54	-1884.0
TRPC6	-1935.0
PLG	-1977.0
PCYOX1L	-2009.0
IGLV1-36	-2030.0
IGKV2-30	-2045.0
NOS3	-2059.0
CALM1	-2081.0
IGLV7-43	-2089.0
IGLV3-19	-2111.0
IGHV3-11	-2134.0
GNG4	-2154.0
IGHM	-2190.0
F2RL2	-2284.0
IGHA1	-2291.0
IGKV3-15	-2297.0
PIK3R5	-2304.0
DOCK7	-2369.0
GNB3	-2397.0
IGKV1-33	-2424.0
IGHV3-30	-2484.0
IGKV4-1	-2532.0
ORM2	-2564.0
MAGED2	-2687.0
SERPIND1	-2722.0
KIF18A	-2742.0
TFPI	-2818.0
ABHD6	-2829.0
IGKV1-17	-2871.0
IGLV2-23	-2878.0
IGLV6-57	-2885.0
IGHV4-59	-2892.0
IGLV2-11	-2905.0
RAPGEF3	-2911.0
IGHV3-33	-2988.0
IGHV4-34	-3016.0
ITIH3	-3017.0
IGKV3-20	-3085.0
IGHV2-70	-3138.0
DGKH	-3178.0
KIF15	-3249.0
IGLV1-44	-3258.0
HRAS	-3382.0
AAMP	-3636.0
MIF	-3863.0
IGKV3D-20	-3894.0
ANGPT2	-3990.0
INPP5D	-4038.0
VAV2	-4055.0
IGLV3-1	-4159.0
JCHAIN	-4240.0
ANGPT4	-4384.0
IGKC	-4428.0
RBSN	-4542.0
IGHV4-39	-4582.0
GPC1	-4627.0
DOCK3	-4640.0
ATP2A1	-4667.0
IGLV3-21	-4735.0
IGLV1-40	-4788.0
SOD1	-4862.0
KIF26A	-4925.0
IGLV3-25	-4933.0
IGLV1-51	-4956.0
MFN1	-4966.0
CDK2	-5006.0
ATP2B4	-5030.0
GUCY1B2	-5054.0
ITGA6	-5094.0
GNG7	-5198.0
IGLC7	-5281.0
IGLV8-61	-5427.0
IGKV1-12	-5446.0
IGLC3	-5477.0
CARMIL1	-5482.0
IGLC2	-5510.0
P2RX6	-5541.0
IGKV2D-28	-5634.0
DGKZ	-5681.0
SOS1	-5700.0
SLC7A11	-5719.0
IGKV2-28	-5808.0
IGLV5-45	-5869.0
IGLV3-27	-5874.0
IGLV1-47	-6018.0
IGLC1	-6157.0
ITIH4	-6208.0
L1CAM	-6358.0
SERPINF2	-6574.0
BRPF3	-6615.0
SLC7A6	-6690.0
KIF21B	-6702.0
PPIA	-6766.0
KIF28P	-6770.0
ORAI1	-7096.0
IGLV3-12	-7358.0
TGFB2	-7492.0
PDE9A	-7584.0
ITPR1	-7629.0
SELENOP	-7771.0
GNG2	-7795.0
RAD51C	-7807.0
KIF20B	-7822.0
NHLRC2	-7835.0
TGFB3	-7891.0
VEGFB	-7929.0
DGKA	-7980.0
PRKCE	-8001.0
CABLES2	-8110.0
DGKQ	-8149.0
ATP2B1	-8286.0
IGLV2-14	-8345.0
TEX264	-8366.0
KLC4	-8376.0
CDC37L1	-8470.0
PRKG2	-8477.0
IRF1	-8510.0
RASGRP2	-8529.0
PDGFB	-8577.0
DAGLA	-8578.0
KIFAP3	-8619.0
SH2B1	-8670.0
SRC	-8820.0
KIF5C	-8865.0
KIF5A	-8869.0
KLKB1	-9019.0
KLC2	-9059.0
ATP1B1	-9118.0
PTGIR	-9126.0
WEE1	-9145.0
CD244	-9216.0
CBX5	-9272.0
CABLES1	-9302.0
TRPC3	-9343.0
ZFPM2	-9423.0
KDM1A	-9430.0
PIK3R1	-9505.0
F2R	-9750.0
PPIL2	-9793.0
GATA2	-9800.0
A2M	-9870.0
SIRPG	-9884.0
FAM3C	-10062.0
PROC	-10098.0
ZFPM1	-10195.0
ITPR3	-10308.0
DGKK	-10314.0
ABHD12	-10401.0
SIN3A	-10493.0
DOCK9	-10708.0
DOCK10	-10728.0
ITGA3	-10750.0
PROCR	-10802.0
ITGAL	-10847.0
TP53	-10893.0
HABP4	-10921.0
ITGA4	-11043.0
CTSW	-11117.0
PLCG1	-11120.0
SERPING1	-11197.0
PPP2R5C	-11265.0
DGKE	-11390.0
CD74	-11419.0
AKAP1	-11442.0
LGALS3BP	-11459.0
PRKCZ	-11629.0
KIF26B	-11663.0
FYN	-11675.0
LAT	-11694.0
KIF19	-11733.0
CD2	-11805.0
KIF21A	-11837.0
LCK	-11838.0
GATA6	-11928.0
PRKACB	-11959.0
KIF3A	-11972.0
RASGRP1	-11974.0
PIK3R3	-12015.0
GNGT2	-12086.0
CD47	-12114.0
PRKCQ	-12127.0
YES1	-12142.0
GATA3	-12191.0
PAFAH2	-12322.0
PRKCH	-12324.0
KIF22	-12358.0
SPN	-12375.0

---

Metabolism

Metabolism

	635
set	Metabolism
setSize	1772
pANOVA	1.65e-22
s.dist	0.14
p.adjustANOVA	2.81e-20

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PPARG	9522
PLBD1	9521
CTSA	9514
IDH1	9507
VCAN	9505
CYP1B1	9502
NMNAT2	9500
CYP19A1	9497
IMPA2	9493
PLB1	9490
MGST1	9482
PGD	9481
BST1	9480
DSE	9479
FAH	9459
TALDO1	9456
KCNG2	9455
GNA15	9452
HADHB	9450
CD36	9444

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PPARG	9522
PLBD1	9521
CTSA	9514
IDH1	9507
VCAN	9505
CYP1B1	9502
NMNAT2	9500
CYP19A1	9497
IMPA2	9493
PLB1	9490
MGST1	9482
PGD	9481
BST1	9480
DSE	9479
FAH	9459
TALDO1	9456
KCNG2	9455
GNA15	9452
HADHB	9450
CD36	9444
HSD3B7	9441
PLIN3	9437
PGAM1	9435
ACSS2	9430
PRKACA	9429
GGT1	9426
PYGL	9417
SLC25A37	9415
SULT1B1	9409
PKM	9391
ADIPOR1	9390
HK3	9385
CA1	9380
BLVRB	9379
PCTP	9376
ACOX2	9373
GAPDH	9368
GNS	9360
PLCD3	9352
TSPO	9351
GNG10	9349
MAOA	9346
PGM2	9344
TKT	9342
OPLAH	9330
TNFAIP8L3	9316
GPX1	9314
CDA	9310
PLD1	9306
IMPDH1	9294
ALDH4A1	9281
PFKFB4	9271
HK2	9266
PC	9263
LTA4H	9261
CHP1	9258
AGPAT2	9256
TPST1	9251
ALDOA	9249
GSR	9235
TK2	9234
NMNAT1	9228
OAZ1	9221
ACSL1	9217
SGMS2	9213
ALAS2	9196
CES1	9192
OLAH	9184
PLA2G4A	9180
BSG	9172
DPYD	9166
ACER3	9165
DGAT2	9158
VNN2	9153
PTGR1	9126
CRLS1	9116
FIG4	9115
CERS2	9108
VNN1	9092
HYAL2	9088
GSTO1	9084
LRP1	9080
SBF2	9078
HK1	9071
MTMR3	9069
ARF1	9064
AK4	9062
GM2A	9059
PIK3CB	9038
SLC6A8	9036
VAPA	9033
NEU1	9029
INPPL1	9028
SLC2A3	9021
CARM1	9020
GYG1	9013
BCKDK	9010
GLUL	9006
G6PD	9004
PAPSS1	9003
ALOX5	9001
LYVE1	8999
GNAQ	8993
SUMF1	8991
ADCY3	8984
GK	8973
GBA	8969
PPT1	8950
PNPLA2	8939
BPGM	8935
MTF1	8925
NUDT16	8923
CRAT	8920
PLCB3	8916
PISD	8908
CHST15	8905
CYB5R3	8903
ME1	8892
ENO1	8890
TBXAS1	8862
ACOX1	8859
HSD17B4	8858
CHPT1	8846
GALK1	8842
B4GALT5	8830
SLC19A1	8822
NUP58	8820
ITPKC	8818
GNG5	8815
OAT	8814
OAZ2	8810
PHKB	8809
FAR2	8808
ACSL4	8802
SLC16A3	8783
SGMS1	8782
HEXB	8776
ARG1	8759
FAR1	8754
PLA2G15	8747
PECR	8739
GLCE	8735
SERINC2	8733
AMPD3	8732
GLB1	8725
TCN2	8721
SORD	8716
GCKR	8713
ELOVL3	8710
MGST2	8706
ETHE1	8705
HADHA	8694
PGK1	8672
ST3GAL2	8669
SMARCD3	8668
BMX	8664
ALDH3B1	8663
ETFA	8658
PFKFB3	8656
PGS1	8654
GDE1	8642
LDHA	8637
PDXK	8635
MAOB	8626
NT5C2	8617
LPCAT3	8609
PRKAR1A	8607
LPCAT2	8606
PUDP	8603
UPP1	8593
SPTLC1	8588
GLRX5	8581
NQO2	8575
LPGAT1	8574
GLA	8570
CACNA1E	8552
SPTLC2	8547
ACSS3	8546
GNPDA1	8541
MBOAT7	8536
ASAH1	8529
GPCPD1	8527
SLC44A1	8526
PHKA2	8524
ALAD	8514
GMPR	8509
DERA	8500
MLX	8497
PSMB7	8485
GLTP	8477
HPSE	8476
PTGS1	8467
PTEN	8460
MTHFS	8455
POR	8454
SLCO2B1	8450
GALC	8443
NDUFB3	8430
FUT7	8428
ALOX15B	8427
PNP	8419
PSMD4	8402
SDHC	8390
MBOAT2	8362
ENTPD1	8360
VDR	8348
CD44	8333
HNMT	8317
SLC27A1	8305
GNB1	8294
ACAA1	8292
ACADVL	8290
TXN	8285
HMOX1	8278
COMT	8273
MTHFD2	8267
PLIN2	8261
PSME3	8251
NDUFB9	8237
PPP2CA	8234
CSGALNACT2	8228
SP1	8193
TXNRD1	8192
HAAO	8183
GPAT3	8177
NDUFAF1	8167
AGPAT1	8158
NDST1	8156
IQGAP1	8152
LYPLA1	8143
GNB2	8141
GBE1	8137
CHSY1	8116
SEC24D	8115
LBR	8102
PSMB5	8101
ALDH2	8095
HMGCR	8094
COX15	8082
GNAI2	8075
UQCRH	8073
ETFDH	8052
ARNT	8047
MTMR14	8032
ACOT8	8018
IPMK	8014
HSD17B11	8008
ENTPD7	8002
NCOR2	7985
BCAT1	7970
SLC9A1	7969
GAA	7968
MTMR10	7964
PLPP3	7955
SRD5A1	7951
PFKFB2	7946
RAB4A	7941
DDAH2	7939
GLRX	7932
NUP214	7921
PRKAR1B	7918
ABHD5	7915
GNAS	7909
NDST2	7892
CERT1	7889
TBL1X	7887
ALOX5AP	7881
MTMR6	7878
SLC35D2	7872
UQCRC1	7859
PCYT1B	7858
MPST	7854
PSMD6	7846
ACSL3	7840
ALAS1	7804
CHPF2	7803
NADK	7774
HAL	7762
TST	7744
GLIPR1	7739
ARF3	7732
GUSB	7723
COX7A2L	7719
PPP2CB	7712
TMLHE	7710
PNPLA8	7709
ELOVL7	7706
FADS1	7699
MGLL	7694
ETFB	7688
COASY	7672
GMPR2	7668
SLC25A44	7662
SEC24A	7660
SPHK1	7657
SLC36A4	7655
NFYC	7653
SEPHS2	7651
RGL1	7647
ATP5PD	7637
DHRS7B	7629
SULT1A1	7624
PSMD9	7620
PDSS1	7619
CDK19	7618
SAMD8	7614
HPD	7593
SDHB	7587
PANK2	7583
NDUFB1	7578
ARSB	7572
CRYM	7565
ALOX12	7559
SUCLA2	7558
GPD2	7555
ATP5PB	7551
MED8	7535
NAMPT	7525
MLXIPL	7517
RXRA	7495
AHR	7479
NUDT4	7423
CKM	7420
HPGD	7416
NR1H2	7415
NAPRT	7412
PSMD2	7411
MANBA	7386
STARD3NL	7374
FDFT1	7372
ARSD	7365
PLD3	7364
ABCD1	7346
GNB4	7336
SEC23A	7335
FBP1	7330
PSMA1	7329
FUT4	7307
RAP1A	7305
DLD	7303
UGP2	7284
SLC25A11	7278
G0S2	7272
PIK3R6	7270
COQ2	7254
IDI1	7247
PSMD1	7241
HSD17B12	7181
PLD2	7180
RPL26L1	7176
PSMB3	7171
SPR	7165
GYS1	7157
PSAP	7145
CSAD	7121
AZIN1	7119
RAB5A	7103
EXT1	7098
PSMA7	7096
RAB14	7095
PCBD1	7093
ELOVL1	7088
LRP10	7070
PPP1CB	7064
PSMC1	7021
NDUFAF3	6981
SDHD	6963
OSBPL8	6960
CBS	6946
ABHD3	6943
KYNU	6934
SLC22A5	6929
ME2	6915
UQCR11	6907
FECH	6882
INPP5A	6880
MAN2B1	6878
HACD4	6870
PNPLA6	6863
ITPK1	6851
CYP51A1	6844
TIMMDC1	6822
PCYT1A	6816
PSMB6	6813
RRM2B	6798
PYCR1	6789
TPI1	6786
PTDSS1	6778
UPB1	6772
GNPAT	6753
MED20	6743
PRKAR2B	6741
VKORC1	6728
PDSS2	6723
NAT1	6718
ST3GAL6	6701
SREBF2	6695
ATP5F1C	6687
DHCR7	6676
PSMF1	6659
UBB	6639
SDC4	6637
PSMC6	6635
COX8A	6611
SMS	6610
MGST3	6607
LMBRD1	6582
PSAT1	6580
CDS2	6557
PSMD12	6556
SERINC3	6548
SREBF1	6539
CPT2	6538
ATP5MF	6519
AOC1	6509
ADI1	6500
ATP5F1B	6497
GNG11	6495
NUDT19	6494
SAR1B	6479
RDH11	6466
ESD	6464
NDUFA4	6459
AHCYL1	6456
PIP5K1B	6450
OCRL	6442
ATP5F1A	6441
CMBL	6437
INSIG2	6430
ABHD4	6425
OSBPL9	6404
PSPH	6403
AOC2	6402
RUFY1	6399
SAMHD1	6397
CSNK2A2	6388
ATP5PF	6373
HPRT1	6371
NDUFS1	6348
CES2	6341
SMOX	6332
PPP1CC	6330
CHST13	6326
UQCRFS1	6325
LRP12	6321
SYNJ1	6296
MMADHC	6291
ISCA1	6287
GPI	6284
CYP4F3	6259
UGCG	6247
PSMD11	6231
DBI	6227
CDIPT	6222
MED25	6209
COX5B	6207
CSNK2A1	6199
MTM1	6198
LDLR	6183
TCN1	6182
NDUFS5	6178
DEGS1	6169
COX5A	6168
PRKAR2A	6166
PPIP5K2	6151
PPCS	6144
ATP5F1E	6142
EHHADH	6140
EP300	6129
PIP5K1A	6110
ABCA1	6109
NDUFC2	6093
BCKDHA	6091
DNM2	6089
NDUFS2	6080
PGLS	6079
MED13L	6077
CHKA	6073
PIK3CD	6046
GDPD3	6027
FABP5	6021
ELOVL5	6011
NDUFA6	6009
ACOX3	5995
PSMA6	5970
ORMDL2	5967
PSMD7	5963
SUCLG1	5961
NT5M	5959
PDK4	5953
PSMD13	5948
ESRRA	5943
SGSH	5912
AFMID	5910
ATP5MC3	5906
NCOR1	5887
APOA2	5879
CPNE3	5872
B3GNT2	5868
PTDSS2	5867
UQCRC2	5852
PHYKPL	5845
PGM1	5843
ITPR2	5842
ASL	5839
ISCA2	5823
HMBS	5822
NDUFB10	5812
CERS6	5795
PITPNM1	5791
SERINC1	5786
ST3GAL4	5781
NCOA6	5773
BLVRA	5763
NDUFAB1	5759
PSMD8	5757
SEC13	5748
TPST2	5725
NDUFA1	5718
ABCC3	5717
NUDT3	5716
SPNS2	5710
PLA2G12A	5705
PLAAT1	5692
TNFAIP8L2	5671
COX6B1	5667
COQ5	5633
ARG2	5626
NDUFA7	5623
RHCE	5621
B3GALNT1	5619
ADPGK	5602
STAB2	5569
G6PC	5568
GLUD1	5567
DHTKD1	5562
SYT5	5548
SLC35B3	5546
ACAT1	5542
ATP5MG	5512
MBOAT1	5500
AGPS	5495
SULT1A4	5483
MCAT	5450
ACOT9	5446
ACSM2A	5445
GSTZ1	5438
GUK1	5436
ACOT13	5423
RPS9	5421
AMPD2	5418
SDC2	5397
GCLM	5391
SUOX	5380
GCHFR	5356
HMGCL	5349
NDUFC1	5343
PSMA2	5339
FDPS	5335
B3GALT4	5332
SAT1	5327
RIDA	5326
ACACA	5315
DECR1	5313
DGAT1	5306
TKFC	5285
MED16	5278
ADCY4	5270
NUDT9	5244
HYAL3	5229
SLC3A2	5222
NDUFV3	5214
NME4	5208
ALDH1L2	5196
NFS1	5188
PIAS4	5184
DHFR	5167
RAE1	5164
ACLY	5159
GPX4	5150
OSBPL2	5117
HAGH	5104
PTGES	5102
COX6A1	5095
ADSL	5085
CPT1A	5077
CYP2C9	5042
MTHFR	5031
GALE	5026
ADIPOR2	5016
PIK3R2	5010
PLCG2	5006
ASRGL1	4994
CRYL1	4975
NDUFA2	4966
APIP	4962
SUMO2	4961
UROD	4960
SLC25A1	4955
ECSIT	4918
FUT1	4899
UCK1	4856
CHST11	4824
ACAD10	4823
AGPAT3	4809
STARD10	4808
NDUFA8	4804
ATP5PO	4794
FDXR	4766
PTGS2	4753
ACOXL	4749
HSD17B13	4718
SLC22A1	4716
COQ7	4706
HDAC3	4673
PLCB2	4665
SPTSSA	4652
TXN2	4651
TK1	4644
PIK3CA	4629
PSMD3	4618
KYAT3	4615
NSDHL	4594
PPP2R1A	4589
LRP8	4568
TBL1XR1	4556
MPC2	4555
NDUFB4	4553
HACD1	4548
FHL2	4524
HS6ST1	4523
NUP50	4521
RPL3L	4503
NUBP1	4501
NCOA1	4483
COX7B	4465
STS	4459
SLC16A1	4455
SCP2	4454
UBC	4439
NT5C3A	4437
TPMT	4422
OSBPL6	4419
NNT	4407
TACO1	4406
MED18	4396
MED26	4395
UQCR10	4378
PARP4	4362
SEM1	4348
VDAC1	4347
ACADS	4297
GNG8	4296
B4GALT1	4292
NDUFV2	4288
PDHX	4282
MAN2B2	4281
VKORC1L1	4256
GLYAT	4252
PDK1	4249
NDUFA13	4244
PDHB	4233
NDUFB6	4218
SQLE	4211
ACO2	4209
MDH2	4207
COX4I1	4191
HSD17B10	4182
GPAT4	4177
HYAL1	4164
NDUFS6	4155
OGDH	4136
PTGES3	4125
GSTM5	4119
CSGALNACT1	4102
HSD17B2	4085
PSMB2	4084
SULT1A3	4082
PPP1CA	4069
AOC3	4067
UGDH	4065
MAPKAPK2	4054
SCD	4026
IP6K1	4023
COQ10B	3989
PPARGC1A	3988
NDUFS4	3986
SRD5A3	3971
CSNK2B	3969
ALDH6A1	3964
SLC25A20	3958
G6PC3	3915
NDUFB5	3892
CYP27A1	3877
HSD11B2	3838
UQCRB	3834
ACSM6	3832
PLA2R1	3812
HMMR	3808
FABP2	3805
MED22	3802
MMUT	3791
RNLS	3723
MID1IP1	3706
HS2ST1	3691
CS	3688
ALB	3668
HSD17B1	3654
CPTP	3651
AKT1	3614
SEC24B	3608
AMD1	3599
CACNA1D	3582
CA2	3570
PRPS2	3562
NUDT18	3553
ERCC2	3547
LIPH	3546
AKR1B15	3541
MTHFD2L	3536
SURF1	3532
NCOA3	3522
NFYA	3506
RHD	3505
ARSA	3486
MOCOS	3461
PXMP2	3436
PSMD5	3426
CREBBP	3423
ACAA2	3421
PIP5K1C	3419
SLC6A12	3414
STARD7	3407
NADSYN1	3392
PSMB1	3374
RFK	3348
STARD3	3342
SGPL1	3332
GNAI1	3329
PGM2L1	3328
PMVK	3317
ACBD7	3315
IDH3G	3314
PHGDH	3301
IPPK	3279
ODC1	3266
GNA11	3259
PDK3	3252
MED19	3243
MED4	3215
PIKFYVE	3187
TMEM86B	3138
PEMT	3103
NUP98	3101
MED17	3084
TYMP	3083
TPH2	3082
NUP37	3074
CYC1	3047
NAGS	3032
SLC7A5	3012
GLB1L	2992
PANK3	2980
GBA2	2974
ATP5F1D	2968
MBTPS1	2966
UQCRQ	2960
ATP5MC2	2956
MTMR4	2951
PHOSPHO1	2944
HSCB	2935
ALDH9A1	2884
FH	2879
POMC	2855
SPHK2	2827
CA4	2826
DGUOK	2820
KCNB1	2784
TAZ	2754
NDUFAF7	2726
ABO	2725
SLC44A2	2700
DHCR24	2694
ATP5ME	2664
PSMD14	2611
SDC3	2599
PSMC2	2598
RPE	2589
AKR7A2	2568
MSMO1	2557
LPL	2545
MED13	2533
PSMB4	2523
ABCC5	2477
SMPD2	2476
NDOR1	2458
GLYATL2	2451
KPNB1	2430
PPP2R5D	2421
AK2	2414
SLC37A2	2350
CTPS2	2345
NDUFB7	2292
STK11	2289
ADRA2A	2271
GCAT	2234
TTPA	2230
PTPMT1	2213
VAPB	2194
PLPP2	2186
CIAO2B	2179
PLCH1	2174
INMT	2172
NDUFAF2	2133
NDUFS7	2118
PPA2	2096
SDSL	2091
ACER2	2074
RPS27L	2061
CBR1	2037
MED12	2034
GNMT	2027
PRKAG2	2015
MDH1	1995
MTRR	1994
PSMC3	1976
CAV1	1969
PPA1	1934
ENPP2	1925
GDA	1908
SLC46A1	1882
CCNC	1877
SPTLC3	1857
FDX1	1854
NME2	1850
PIK3CG	1833
SLC25A19	1785
NME1	1742
PIK3C2G	1737
UGT1A1	1670
PHKG2	1631
PIK3C3	1619
SLC16A8	1608
PSMD10	1559
HS3ST2	1510
CYP3A43	1492
FADS2	1486
MED31	1462
NDUFA11	1458
MTMR9	1453
AKR1A1	1447
RPIA	1441
HSP90AA1	1326
LRP2	1307
TECRL	1306
HEXA	1261
PTGR2	1238
CA13	1227
PLCB1	1197
GCK	1193
HTD2	1183
GSTM4	1181
NDUFB11	1172
CHST14	1138
PRKCA	1132
SMPD1	1129
CEPT1	1127
UBA52	1121
PRKD3	1104
NCOA2	1092
NUDT7	1086
B4GALNT2	1079
DARS1	1069
PLA2G4D	1068
ALDH7A1	1060
GRHPR	1030
NDUFB8	965
UCP2	913
GNG3	890
CSNK1G2	887
NDUFS3	884
MT-ND4	840
PLEKHA4	838
ALDH3A2	833
PPARA	813
DECR2	783
NUP62	769
TRMT112	738
GSS	715
NPAS2	712
COX6C	706
MT-CO1	684
ABCC1	576
COX7C	564
ADH1B	519
GNB5	512
ST3GAL3	505
NDUFA3	503
RETSAT	498
PYGB	492
ECI1	486
AKR1C1	473
AHCY	466
MT-ND6	459
TYMS	458
PGP	437
APOM	429
ASPA	427
RPS4Y1	424
B4GALT4	391
THRAP3	388
MTHFD1L	371
CACNB3	370
AACS	351
SLC25A16	348
GLDC	318
SLC25A21	305
WASL	299
AK9	259
MED7	224
APOE	218
POLD1	204
PANK1	195
FAHD1	174
TPO	148
GSTP1	135
COX16	132
ADCY9	123
QARS1	86
MBTPS2	83
NDUFS8	81
MT-CO2	48
MT-CO3	40
CYP1A2	38
RPL36AL	32
RPLP1	19
LHPP	11
FAM120B	-8
AANAT	-41
ENPP6	-56
FMOD	-59
ABCG2	-77
VAC14	-124
GSTM1	-140
GADL1	-171
LCLAT1	-177
RRM2	-183
MED14	-203
HGD	-235
PPP2R1B	-241
IYD	-255
RPS24	-263
DCXR	-290
PPCDC	-292
ACSF3	-347
LTC4S	-353
FAU	-362
FMO3	-371
SLC25A13	-412
AASDHPPT	-458
TNFAIP8	-460
GRHL1	-492
PLAAT2	-544
MED11	-560
CYP46A1	-580
PSMA4	-616
CPOX	-639
NME3	-652
PCK2	-685
IMPA1	-687
FASN	-690
GGT5	-695
SHMT1	-717
ACADL	-726
UBE2I	-764
SLC27A3	-798
RANBP2	-820
ACOT11	-823
MED6	-842
PSMC5	-863
ACAD9	-879
GPS2	-889
PNMT	-916
CYP4F8	-925
RPL15	-963
AIMP2	-988
RPLP0	-1000
PFKM	-1014
GGPS1	-1066
BPNT1	-1073
MINPP1	-1095
MPC1	-1097
SULT1C2	-1102
RPL8	-1187
AUH	-1196
AKR7L	-1205
SERINC4	-1223
ACSBG1	-1236
CBR4	-1239
STAR	-1244
ACBD5	-1284
CHST5	-1306
ACADM	-1308
CYCS	-1334
PLEKHA2	-1351
ETNK1	-1401
EXT2	-1405
MED28	-1429
RPS26	-1430
MOGAT3	-1460
RPL28	-1462
MIOX	-1466
COX14	-1496
IDH3B	-1504
CMPK1	-1520
GPT2	-1542
HILPDA	-1566
ADCY6	-1608
RPL22L1	-1619
GSTK1	-1620
INPP1	-1654
DCTPP1	-1664
MTMR12	-1677
HACD2	-1711
DSEL	-1727
NDUFA12	-1728
PRELP	-1738
MARCKS	-1739
PLEKHA6	-1745
RPS13	-1749
NUDT12	-1752
SLC10A1	-1762
ADO	-1804
CHDH	-1816
ISCU	-1833
ABCB7	-1842
GSTM3	-1867
RPL9	-1872
SLC19A3	-1900
ACP5	-1920
RPL7	-1955
CDK8	-1971
HMGCS1	-1972
PTS	-1981
INPP5K	-2034
NOS3	-2059
EEF1E1	-2072
B3GAT2	-2076
ABCC2	-2079
CALM1	-2081
RIMKLA	-2082
RPS8	-2083
MT-ATP6	-2096
DHFR2	-2143
GNG4	-2154
MT-ND5	-2166
MTMR2	-2216
AMDHD1	-2226
MT-CYB	-2254
ECHS1	-2265
PIK3R5	-2304
MFSD2A	-2309
OXCT2	-2322
ADK	-2326
NDUFAF6	-2331
ACSM2B	-2360
PIP4K2A	-2365
GCDH	-2370
GNB3	-2397
ALDOB	-2431
ACMSD	-2493
PYCR2	-2496
SHPK	-2528
CERS5	-2540
LDHAL6A	-2551
SEC24C	-2569
MARS1	-2588
PI4KA	-2601
IDS	-2621
NMNAT3	-2629
OSBP	-2645
CYP4F12	-2701
DPEP2	-2705
ARV1	-2720
SLC25A28	-2721
APRT	-2766
PAPSS2	-2810
CERS3	-2840
CA6	-2843
PLA2G4C	-2845
DNPH1	-2846
RPL27	-2855
HIBCH	-2884
SLC26A2	-2893
DPEP3	-2894
ADCY2	-2896
RAPGEF3	-2911
B3GAT3	-2928
STARD5	-2943
BCAT2	-2962
NUDT15	-2973
DIO1	-2981
AK6	-2996
RPL39	-3006
NUP85	-3049
MT-ATP8	-3067
PSMB8	-3076
PLEKHA8	-3080
IDH2	-3102
NQO1	-3115
CPS1	-3132
AGL	-3136
RBKS	-3142
GSTO2	-3175
EPRS1	-3185
NAXE	-3187
SRR	-3203
PHYH	-3231
SLC23A2	-3248
CACNA1A	-3256
RXRB	-3276
PFKL	-3277
TPK1	-3279
ADCY7	-3286
ACOT7	-3289
RPL23	-3314
CHKB	-3319
PNPLA4	-3322
RPL6	-3354
NUDT1	-3379
MTMR1	-3383
CDS1	-3388
CPNE1	-3397
PITPNM3	-3420
RPL13	-3431
ALDOC	-3438
PPM1L	-3445
ANGPTL4	-3469
HYKK	-3495
THTPA	-3512
PFKP	-3517
DLAT	-3526
SLC44A5	-3527
GPX2	-3533
NUDT5	-3557
MTMR7	-3565
AIP	-3566
GART	-3567
NMRK1	-3570
OSBPL10	-3580
RPL4	-3582
NR1H3	-3597
RPL29	-3611
SLC27A5	-3614
MT-ND1	-3616
PLA2G10	-3617
MT-ND3	-3649
SERINC5	-3658
RPL7A	-3665
RPS15	-3673
NAALAD2	-3680
SC5D	-3695
ACAT2	-3713
GLO1	-3721
CYP3A5	-3761
PLIN1	-3785
ACP6	-3790
MAN2C1	-3805
CYP27B1	-3807
CYP24A1	-3820
SLC27A2	-3831
NEU3	-3833
PLD6	-3870
GLYCTK	-3936
RPL37A	-3946
FA2H	-3949
B3GNT3	-4017
MED1	-4036
INPP5D	-4038
SULT1A2	-4046
STX1A	-4052
PIK3R4	-4062
RPS21	-4079
STARD4	-4084
KCNJ11	-4105
SLC19A2	-4110
B3GALT1	-4134
KYAT1	-4140
CYP2S1	-4149
KDSR	-4187
SCAP	-4189
SIN3B	-4205
PDP1	-4260
DDO	-4276
GPC2	-4280
CYP7B1	-4294
HS3ST1	-4307
SLC23A1	-4335
CHST6	-4347
SCO2	-4351
SLC25A27	-4356
MAT2A	-4359
AMN	-4361
ISYNA1	-4370
PARP9	-4400
NDUFB2	-4446
OAZ3	-4447
PI4KB	-4465
B3GALT6	-4474
RTEL1	-4476
RPS2	-4499
ACBD4	-4503
ACAD8	-4520
RPL31	-4541
CSPG4	-4549
GDPD1	-4554
PDHA1	-4581
CPT1B	-4584
CHD9	-4585
ACY1	-4587
B3GALT2	-4595
ACOT1	-4622
GPC1	-4627
SLC25A14	-4642
LGMN	-4644
RPS16	-4669
RPS3A	-4694
RPS28	-4713
NDUFA5	-4723
MCEE	-4724
XYLT2	-4727
RPL5	-4728
GPC4	-4730
RPL22	-4740
SLC25A12	-4760
NAGLU	-4761
CIAO3	-4772
ARSG	-4773
PYGM	-4777
RARS1	-4794
ENTPD6	-4804
CNDP2	-4820
PITPNM2	-4822
INPP5F	-4865
SHMT2	-4893
FAAH2	-4912
QDPR	-4955
PARP6	-4959
PLEKHA5	-4963
RPS7	-4968
GPAT2	-4997
COX20	-5018
FDX2	-5019
PPARGC1B	-5047
PLEKHA3	-5068
RPL18	-5080
FAAH	-5096
SLC52A2	-5125
PIK3C2A	-5194
GNG7	-5198
ADHFE1	-5216
UGT8	-5219
CERK	-5241
PSMA3	-5285
RPL36	-5287
SLC5A5	-5330
FOLR2	-5337
CERS4	-5342
PAICS	-5367
CA14	-5373
KARS1	-5382
GMPS	-5430
RPL17	-5431
ABCB4	-5440
TGS1	-5441
NUDT13	-5444
RPS14	-5463
MED30	-5484
DBT	-5509
FUT10	-5523
CYB5A	-5527
LPIN3	-5536
ARSJ	-5542
NUP42	-5564
SDHA	-5579
HSD17B3	-5592
AGMAT	-5600
NHLRC1	-5628
SLC5A6	-5629
DHODH	-5633
B4GAT1	-5642
RPS5	-5691
PLPP1	-5711
PSMB10	-5735
RPS15A	-5742
D2HGDH	-5760
AHRR	-5763
PLA2G2D	-5777
SUCLG2	-5783
MTAP	-5790
RPS10	-5793
RPL24	-5799
OSBPL1A	-5816
SLC37A1	-5819
IDUA	-5830
RPL38	-5840
TRIB3	-5843
MVD	-5850
COX10	-5873
CKMT2	-5893
AIMP1	-5902
PRXL2B	-5905
SARS1	-5909
ACSL6	-5913
RPS3	-5914
MED21	-5937
MIGA2	-5952
ORMDL1	-5954
NT5E	-5964
IDO2	-5968
LIAS	-5976
UCKL1	-5984
RPS12	-5987
LYRM4	-6003
CACNB2	-6006
RPL35A	-6015
FTCD	-6024
B4GALT2	-6034
DUT	-6046
FITM2	-6050
PSMA5	-6053
STXBP1	-6059
SEH1L	-6069
RPL18A	-6070
PSME4	-6087
COX18	-6126
PON2	-6147
RPS6	-6160
ENTPD5	-6179
HAS3	-6197
MRI1	-6213
FITM1	-6244
RPS17	-6247
RPL27A	-6257
AKR1C2	-6258
RPL11	-6261
RPL19	-6281
RPS4X	-6285
PDZD11	-6288
RPS23	-6292
SDS	-6313
NUP153	-6321
RPSA	-6323
SLC37A4	-6333
AMT	-6359
RPS25	-6365
RPL37	-6375
PPARD	-6394
PNPO	-6419
LARS1	-6428
ENTPD4	-6452
ZDHHC21	-6453
RPL21	-6458
GGCT	-6517
RPL10	-6534
ABHD10	-6541
MT-ND2	-6560
RPL26	-6612
PI4K2A	-6666
KMO	-6673
PLA2G4B	-6679
RPL10A	-6686
SLC52A1	-6687
PLAAT3	-6706
RPL32	-6709
RPL14	-6710
MOCS3	-6731
ELOVL4	-6768
MED23	-6787
RAN	-6791
RPL34	-6802
PLCE1	-6806
ARNTL	-6811
PIPOX	-6812
NOSIP	-6827
CHAC2	-6837
GATM	-6852
HSP90AB1	-6863
RPL41	-6866
MMACHC	-6876
PNPLA7	-6877
AS3MT	-6880
COX19	-6882
GPD1	-6895
SLC35D1	-6904
NMRAL1	-6922
PTGES2	-6926
LPIN2	-6935
RPS27A	-6938
RPS19	-6965
AMACR	-6980
NDUFA10	-6994
ENO3	-7018
RPL30	-7020
INPP5B	-7024
TPR	-7028
GPHN	-7047
PITPNB	-7049
RPL12	-7053
GAMT	-7054
CPNE7	-7075
RPLP2	-7087
NADK2	-7146
SRM	-7175
POM121C	-7188
KHK	-7193
RPS11	-7243
CYP2J2	-7268
DMAC2L	-7274
MIGA1	-7300
PDPR	-7326
MOCS1	-7346
MECR	-7348
B4GALT7	-7367
ALOX12B	-7374
RPL36A	-7376
MED24	-7387
ACSM3	-7398
XYLT1	-7401
CEMIP	-7418
LPCAT1	-7428
GCH1	-7439
ST3GAL1	-7442
CLOCK	-7460
TM7SF2	-7470
CUBN	-7513
PSMA8	-7606
ATP5MC1	-7616
ITPR1	-7629
GLS2	-7702
SULT2B1	-7719
RPS18	-7744
SCD5	-7756
NUP133	-7762
NAXD	-7769
ACY3	-7770
HSPG2	-7779
PIP4K2B	-7788
GNG2	-7795
ACER1	-7850
MMS19	-7874
CIAPIN1	-7893
UGT2B11	-7930
RPS29	-7940
PCCB	-7976
MED29	-7985
PDK2	-8047
ADH5	-8056
LIPT2	-8065
RPL35	-8092
HS3ST3A1	-8096
COQ9	-8169
PRKAB2	-8172
SLC26A1	-8174
CTH	-8181
NT5C1B	-8182
NRF1	-8183
TSTD1	-8195
RPL13A	-8212
HDC	-8229
ADCY5	-8235
SCLY	-8248
THEM5	-8249
GCSH	-8292
POM121	-8299
CYP2D6	-8301
MVK	-8305
FLVCR1	-8306
ASNS	-8316
TMEM126B	-8346
ITPA	-8350
INPP5E	-8363
AAAS	-8389
PFKFB1	-8393
FLAD1	-8399
PARP10	-8400
PARP8	-8409
GSTA4	-8414
ABCD4	-8420
CBR3	-8424
PHKG1	-8428
LPCAT4	-8430
HIBADH	-8435
HS3ST3B1	-8469
PRKG2	-8477
NUP54	-8479
ENO2	-8498
SYNJ2	-8511
SLC25A15	-8540
RPL3	-8561
AGPAT4	-8576
MED10	-8579
GGT7	-8598
PANK4	-8608
TPH1	-8640
PCCA	-8664
GNPDA2	-8678
PLCD1	-8685
BPHL	-8708
DCK	-8733
BCO2	-8744
GPT	-8754
ADPRM	-8782
B4GALT6	-8785
CHST7	-8793
RPL39L	-8805
MED9	-8812
PEX11A	-8816
SPTSSB	-8818
PRKD2	-8834
NDUFA9	-8864
RPS20	-8886
INPP4B	-8893
DLST	-8906
CES3	-8917
CYP2A6	-8965
CYSLTR2	-8970
MCCC1	-8976
NR1D1	-8980
SARDH	-9008
HELZ2	-9045
MMAB	-9046
HSD17B7	-9066
DBH	-9067
ETNK2	-9115
PSMC4	-9127
MED27	-9191
GALT	-9201
ASAH2	-9218
PRODH	-9223
AK1	-9234
SACM1L	-9235
LIPE	-9245
IDH3A	-9280
CYP4V2	-9298
PODXL2	-9309
MOCS2	-9331
SGPP2	-9332
NT5C	-9361
CYP2E1	-9363
DTYMK	-9425
TECR	-9426
NUBP2	-9439
COQ3	-9453
FUT2	-9498
NDUFAF5	-9499
PIK3R1	-9505
NUP43	-9517
ACSM1	-9529
SLC25A32	-9560
RPL23A	-9567
MLYCD	-9599
INPP4A	-9634
MORC2	-9637
AASS	-9645
IDO1	-9680
ENPP1	-9700
CD320	-9704
RPS27	-9756
CAD	-9762
MED15	-9778
GOT2	-9804
ABHD14B	-9811
SCO1	-9819
GSTM2	-9892
L2HGDH	-9902
PM20D1	-9905
EPHX1	-9912
IMPDH2	-9916
CYP2R1	-9918
AGPAT5	-9925
TNFAIP8L1	-9931
LDHB	-9933
ACACB	-9957
PTPN13	-9962
NFYB	-9964
CIAO1	-9982
PSME1	-9991
ORMDL3	-9997
AK5	-10019
MTMR8	-10026
EEFSEC	-10030
ME3	-10048
NDUFAF4	-10063
LRPPRC	-10081
ACOT2	-10127
CTPS1	-10133
UCK2	-10134
IL4I1	-10164
DCTD	-10167
XYLB	-10178
EPHX2	-10186
PSTK	-10190
ACAD11	-10194
UCP3	-10214
FABP3	-10221
SLC35B2	-10225
B3GNT4	-10231
NUP155	-10233
SLC25A10	-10239
GPAM	-10241
ENOPH1	-10278
ITPR3	-10308
SECISBP2	-10334
PSME2	-10336
MAT2B	-10365
CHPF	-10383
PLPP6	-10392
ACADSB	-10412
BDH1	-10419
NUP107	-10421
UMPS	-10474
GPD1L	-10479
PRSS1	-10480
SIN3A	-10493
ACSL5	-10518
SBF1	-10530
CARNS1	-10534
NUP160	-10557
UBIAD1	-10558
SLC25A17	-10559
LSS	-10583
NUP35	-10611
INSIG1	-10636
FPGS	-10644
IP6K2	-10651
ALOX15	-10676
CARNMT1	-10722
HSD17B8	-10724
NUP210	-10726
B3GAT1	-10732
ACOT4	-10733
CA5B	-10735
GDPD5	-10745
EPM2A	-10751
B4GALT3	-10759
TRAP1	-10796
SELENOI	-10809
NUDT11	-10835
RIMKLB	-10844
HACD3	-10864
PAOX	-10870
CACNA1C	-10875
ALDH1B1	-10876
PTGDS	-10886
ENPP3	-10948
TIAM2	-10979
PPIP5K1	-10998
PFAS	-11033
DEGS2	-11048
DUOX1	-11054
PLCD4	-11061
THEM4	-11069
ACBD6	-11092
ALDH18A1	-11103
RRM1	-11119
PLCG1	-11120
CTRC	-11123
PPAT	-11159
ARSK	-11166
CYB5B	-11192
ATIC	-11196
AZIN2	-11224
CHST2	-11228
PDP2	-11231
ADAL	-11234
SLC2A1	-11236
PPOX	-11262
ACSF2	-11266
PIK3C2B	-11281
SEPSECS	-11289
LIPT1	-11308
N6AMT1	-11314
NUP205	-11321
PSMB9	-11324
PPT2	-11340
PCYT2	-11345
PIP4K2C	-11371
BCKDHB	-11373
NUP88	-11397
COQ10A	-11405
HADH	-11421
LPIN1	-11437
MTHFD1	-11451
NDUFV1	-11466
ELOVL6	-11474
MMAA	-11476
BDH2	-11480
UROS	-11504
ITPKB	-11506
FXN	-11511
COX11	-11539
BRIP1	-11605
TSPOAP1	-11608
DDHD1	-11616
NUP93	-11620
NUP188	-11624
NUBPL	-11628
ESYT2	-11660
GCLC	-11691
OXCT1	-11698
HLCS	-11710
GOT1	-11715
COQ6	-11716
UST	-11728
OSBPL7	-11742
SMPD4	-11747
HACL1	-11751
ALDH1A1	-11765
ECI2	-11768
AGRN	-11770
VAMP2	-11779
DDHD2	-11818
HMOX2	-11819
PARP16	-11830
PLCH2	-11831
CACNA2D2	-11844
PPM1K	-11852
MCCC2	-11857
GLS	-11862
PARP14	-11869
IARS1	-11897
AKR1B1	-11917
PRKACB	-11959
OSBPL3	-11960
CD38	-11970
CROT	-11973
RORA	-11979
PI4K2B	-11980
MTR	-11996
NAT8L	-11999
CYP2U1	-12000
PIK3R3	-12015
EBP	-12029
SUMF2	-12038
ACSS1	-12065
CKB	-12070
PRPS1	-12077
ST6GALNAC6	-12085
GNGT2	-12086
AKR1C3	-12104
QPRT	-12106
AGK	-12120
PLA2G6	-12122
PLEKHA1	-12149
BTD	-12170
NDC1	-12173
OSBPL5	-12194
FUT11	-12201
SGPP1	-12210
ABCB1	-12224
PLAAT4	-12230
SMPD3	-12234
ESYT1	-12237
TNFRSF21	-12254
IVD	-12260
CYP4F22	-12271
ADA	-12297
B3GNT7	-12298
AKAP5	-12326
PLD4	-12365
CHST12	-12372

---

Platelet activation, signaling and aggregation

Platelet activation, signaling and aggregation

	830
set	Platelet activation, signaling and aggregation
setSize	221
pANOVA	1.35e-20
s.dist	0.363
p.adjustANOVA	2.05e-18

Top enriched genes

Top 20 genes

GeneID	Gene Rank
F5	9485
CYB5R1	9460
GNA15	9452
CD36	9444
CLU	9371
GNG10	9349
APLP2	9347
GRB2	9304
QSOX1	9298
CD63	9287
ALDOA	9249
LHFPL2	9224
FERMT3	9223
PLA2G4A	9180
APP	9177
SERPINA1	9168
MAPK14	9104
ACTN1	9094
SYK	9076
PIK3CB	9038

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
F5	9485
CYB5R1	9460
GNA15	9452
CD36	9444
CLU	9371
GNG10	9349
APLP2	9347
GRB2	9304
QSOX1	9298
CD63	9287
ALDOA	9249
LHFPL2	9224
FERMT3	9223
PLA2G4A	9180
APP	9177
SERPINA1	9168
MAPK14	9104
ACTN1	9094
SYK	9076
PIK3CB	9038
STXBP2	9035
PRKCD	9008
GNAQ	8993
MAPK3	8953
CLEC1B	8931
CRK	8906
ITGA2B	8893
F13A1	8876
HGF	8863
TOR4A	8861
VTI1B	8850
GNG5	8815
RAC1	8793
LAMP2	8786
SRGN	8761
APBB1IP	8744
TIMP1	8677
TLN1	8525
ARRB2	8490
RHOG	8487
CLEC3B	8480
SELP	8457
RHOA	8319
GNB1	8294
ITGB3	8291
FN1	8284
SYTL4	8256
ANXA5	8210
CFL1	8186
EGF	8179
GNB2	8141
FCER1G	8131
CAP1	8111
GNAI2	8075
GAS6	8063
LY6G6F	8023
ORM1	7971
DGKG	7958
GNAI3	7953
VAV1	7896
CALU	7894
RAF1	7879
PECAM1	7855
P2RY1	7852
LYN	7809
SCCPDH	7787
PROS1	7758
MMRN1	7714
MGLL	7694
CDC42	7537
GP9	7506
MAPK1	7493
SERPINE1	7483
GP1BB	7470
VEGFA	7467
ABCC4	7434
STXBP3	7424
TAGLN2	7367
SPARC	7339
GNB4	7336
VCL	7328
RAP1A	7305
PIK3R6	7270
PSAP	7145
PRKCB	7097
HSPA5	7029
F8	7022
WDR1	6976
VEGFC	6906
GP6	6818
VWF	6641
GNG11	6495
TUBA4A	6484
GTPBP2	6331
TMSB4X	6295
GP1BA	6279
PDPK1	6136
PTPN6	6096
PPBP	6042
THBS1	5951
CD9	5940
ITPR2	5842
GNA13	5836
DAGLB	5820
PTPN1	5722
PF4	5707
YWHAZ	5624
A1BG	5559
PFN1	5459
PHACTR2	5410
PTPN11	5314
PDGFA	5293
CSK	5219
ECM1	5176
RAC2	5163
TGFB1	5153
TBXA2R	5148
ACTN4	5049
PIK3R2	5010
PLCG2	5006
OLA1	4914
VAV3	4894
P2RY12	4821
F2RL3	4773
PIK3CA	4629
PTK2	4462
CD109	4316
GNG8	4296
SHC1	4161
ALB	3668
AKT1	3614
RAB27B	3386
GNA12	3367
ENDOD1	3361
GNAI1	3329
TIMP3	3296
GNA11	3259
RAP1B	3206
CHID1	2811
MPL	2634
MANF	2550
ADRA2A	2271
PLEK	1999
ARRB1	1998
CFD	1984
PIK3CG	1833
APOOL	1609
GP5	1295
RHOB	1254
TTN	1195
PRKCA	1132
TF	1102
GNG3	890
STX4	606
GNB5	512
FLNA	483
DGKD	-501
TMX3	-775
LCP2	-1156
TRPC6	-1935
PLG	-1977
PCYOX1L	-2009
CALM1	-2081
GNG4	-2154
F2RL2	-2284
PIK3R5	-2304
GNB3	-2397
ORM2	-2564
MAGED2	-2687
ABHD6	-2829
RAPGEF3	-2911
ITIH3	-3017
DGKH	-3178
AAMP	-3636
VAV2	-4055
SOD1	-4862
GNG7	-5198
DGKZ	-5681
SOS1	-5700
ITIH4	-6208
SERPINF2	-6574
BRPF3	-6615
PPIA	-6766
TGFB2	-7492
ITPR1	-7629
SELENOP	-7771
GNG2	-7795
NHLRC2	-7835
TGFB3	-7891
VEGFB	-7929
DGKA	-7980
PRKCE	-8001
DGKQ	-8149
TEX264	-8366
CDC37L1	-8470
RASGRP2	-8529
PDGFB	-8577
DAGLA	-8578
SRC	-8820
TRPC3	-9343
PIK3R1	-9505
F2R	-9750
A2M	-9870
FAM3C	-10062
ITPR3	-10308
DGKK	-10314
ABHD12	-10401
HABP4	-10921
CTSW	-11117
SERPING1	-11197
DGKE	-11390
LGALS3BP	-11459
PRKCZ	-11629
FYN	-11675
LAT	-11694
LCK	-11838
RASGRP1	-11974
PIK3R3	-12015
GNGT2	-12086
PRKCQ	-12127
PRKCH	-12324

---

Signaling by Receptor Tyrosine Kinases

Signaling by Receptor Tyrosine Kinases

	1133
set	Signaling by Receptor Tyrosine Kinases
setSize	414
pANOVA	1.68e-20
s.dist	0.266
p.adjustANOVA	2.29e-18

Top enriched genes

Top 20 genes

GeneID	Gene Rank
WASF1	9520
GRB10	9439
PRKACA	9429
ATP6V0A1	9423
LAMC1	9387
CTNNA1	9341
GRB2	9304
ATP6V1A	9302
DUSP3	9280
NCF4	9268
CYFIP1	9265
TNS3	9262
ATP6V0D1	9245
FES	9237
NCF2	9190
NCSTN	9186
ATP6V0C	9127
RIT1	9121
MAPK14	9104
FURIN	9075

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
WASF1	9520
GRB10	9439
PRKACA	9429
ATP6V0A1	9423
LAMC1	9387
CTNNA1	9341
GRB2	9304
ATP6V1A	9302
DUSP3	9280
NCF4	9268
CYFIP1	9265
TNS3	9262
ATP6V0D1	9245
FES	9237
NCF2	9190
NCSTN	9186
ATP6V0C	9127
RIT1	9121
MAPK14	9104
FURIN	9075
MAP2K1	9063
ATP6V1B2	9057
ATP6V1D	9047
PIK3CB	9038
CYBB	9031
PRKCD	9008
DLG4	9007
CLTC	9000
KL	8963
MAPK3	8953
CRK	8906
TGFA	8889
HGF	8863
MEMO1	8847
RAC1	8793
ADAM10	8791
FOSL1	8788
PCSK6	8740
AP2M1	8627
CDK5	8616
CDH5	8613
ATP6V0B	8598
ATP6V0E1	8596
IRS2	8569
SOCS6	8557
ATP6V1C1	8539
SPINT1	8446
RALB	8414
RNF41	8389
MAPKAPK3	8382
CLTA	8376
WASF2	8369
RHOA	8319
ITGB3	8291
INSR	8282
PPP2CA	8234
PAK1	8230
LYL1	8221
SPINT2	8206
PAK2	8185
EGF	8179
MKNK1	8170
ATP6AP1	8160
PTPN12	8151
ADAM17	8110
GAB2	8099
STAT3	8098
ATP6V1H	8064
EPN1	8045
ATP6V1E1	8035
AP2S1	8026
MEF2A	8009
PSEN1	7961
RAB4A	7941
PTK2B	7935
VAV1	7896
LYN	7809
PTPRJ	7783
PPP2CB	7712
RPS6KA1	7695
NCKAP1L	7673
SPHK1	7657
TRIB1	7643
SH3GL1	7625
PTPN2	7615
SH2B2	7609
POLR2E	7563
ADAP1	7557
TEC	7549
CDC42	7537
LAMB3	7497
MAPK1	7493
ROCK1	7489
CBL	7480
VEGFA	7467
NCKAP1	7462
FRS3	7343
SPARC	7339
NCF1	7334
DOCK1	7314
RAP1A	7305
AP2A2	7257
FLT3	7196
TCIRG1	7188
PRKCB	7097
ABI1	7082
SRF	7079
KIDINS220	7069
DNM3	7045
THBS3	7037
BRK1	7032
STAT5A	6965
TAB2	6964
SPRED2	6936
STAT5B	6925
CYBA	6922
VEGFC	6906
AP2A1	6832
WASF3	6808
JUNB	6806
MAP2K2	6794
FLT1	6793
GFAP	6713
POLR2J	6671
UBB	6639
AHCYL1	6456
USP8	6418
CTNNB1	6408
YWHAB	6385
APH1B	6280
ELMO1	6258
PXN	6230
NEDD4	6201
SH3KBP1	6173
STAM2	6159
PTPN18	6149
ROCK2	6138
PDPK1	6136
EP300	6129
ITGAV	6106
PTPN6	6096
DNM2	6089
SHB	6026
IGF1R	5990
PDGFC	5986
AREG	5977
LAMB1	5966
PTK6	5956
THBS1	5951
BAX	5916
NCOR1	5887
STAT6	5884
ATP6V1F	5878
PDGFRA	5858
ITPR2	5842
RANBP9	5813
PSENEN	5735
ATP6V1E2	5730
PTPN1	5722
ATF1	5706
GAB1	5679
FOS	5460
GTF2F2	5434
NRAS	5363
PTPN11	5314
POLR2L	5305
PDGFA	5293
PAG1	5268
CSK	5219
HNRNPM	5195
COL9A3	5126
MAPKAP1	5057
COL6A3	5053
HBEGF	5013
PIK3R2	5010
GTF2F1	4951
NCK2	4934
ID1	4927
VAV3	4894
PCSK5	4863
GRAP2	4690
PIK3CA	4629
POLR2F	4604
SGK1	4595
PPP2R1A	4589
HGS	4513
PTK2	4462
UBC	4439
ELMO2	4397
DUSP6	4357
SHC2	4183
ITGA2	4168
SHC1	4161
EPS15	4138
APH1A	4133
CDC37	4096
MAPKAPK2	4054
SHC3	3974
CRKL	3966
SOCS1	3947
MAP2K5	3940
ATP6V1G1	3931
HNRNPF	3929
FGF2	3920
SH2B3	3910
MAPK13	3865
MAPK11	3826
ANOS1	3822
GGA3	3816
NRG1	3750
KRAS	3702
EPS15L1	3655
AKT1	3614
DNM1	3587
POLR2G	3508
DNAL4	3398
ADORA2A	3293
RAP1B	3206
RAB4B	3137
EGR1	3124
RPS6KA2	3087
NTRK3	3068
RPS6KA3	2973
RALA	2710
JAK2	2691
EPGN	2662
HPN	2625
RANBP10	2553
PTPRO	2501
PPP2R5D	2421
SPRY1	2302
RASA1	2106
ATF2	2085
CAV1	1969
EREG	1888
HSPB1	1863
GALNT3	1805
FER	1761
IRS1	1741
MMP9	1690
PIK3C3	1619
POLR2C	1616
JUND	1549
ARF6	1377
FOSB	1368
NAB1	1342
HSP90AA1	1326
ITCH	1318
BRAF	1308
STAM	1285
VRK3	1281
PRKCA	1132
UBA52	1121
TF	1102
ELK1	1040
GABRG2	996
COL4A2	970
REST	865
MST1	849
CUL5	834
TIAM1	651
LAMB2	501
AKT2	433
POLR2I	396
MLST8	376
NELFB	374
APOE	218
TNS4	100
EGR3	44
PTPN3	-85
ITGB1	-94
PTBP1	-205
BAIAP2	-215
PPP2R1B	-241
MEF2C	-293
ERBB3	-472
ERBIN	-574
DIAPH1	-854
STUB1	-1032
LAMA1	-1044
MAPK12	-1074
CDK5R1	-1089
TCF12	-1233
PLAT	-1242
MAPK7	-1337
CREB1	-1378
EGR2	-1435
COL6A1	-1605
POLR2K	-1783
NRG4	-1875
PLG	-1977
GABRB3	-1992
LAMC3	-2016
NOS3	-2059
CALM1	-2081
ATP6V1C2	-2219
LAMA4	-2252
TIAL1	-2282
DOCK7	-2369
CHEK1	-2481
POLR2B	-2523
AP2B1	-2709
PTPRU	-2724
POLR2H	-2942
POLR2A	-3092
MEF2D	-3094
DUSP7	-3211
LAMA5	-3263
FGFR4	-3293
HRAS	-3382
FRS2	-3433
AAMP	-3636
FLRT2	-3656
COL4A4	-3759
COL4A3	-3896
POLR2D	-4024
VAV2	-4055
PIK3R4	-4062
PAK3	-4184
FGF7	-4247
NRP2	-4282
CHD4	-4515
ARHGEF7	-4583
SPRY2	-4603
DOCK3	-4640
ADAM12	-4744
TIA1	-5344
FGFR1	-5352
JUP	-5353
S100B	-5457
MST1R	-5615
SOS1	-5700
PGF	-5814
TRIB3	-5843
NCBP1	-5853
HNRNPA1	-5924
MUC20	-5962
TLR9	-5999
DUSP4	-6287
FGF23	-6622
RPS27A	-6938
FLT4	-7216
PTPRK	-7262
RBFOX2	-7280
ITPR1	-7629
PSEN2	-7718
VEGFB	-7929
HNRNPH1	-7932
PRKCE	-8001
NTRK1	-8193
THBS4	-8396
CTNND1	-8403
PDGFB	-8577
FGF22	-8607
SPRED1	-8639
TPH1	-8640
STMN1	-8663
ESRP2	-8691
NRP1	-8717
FGF9	-8761
SRC	-8820
CILP	-8873
ESR1	-9122
FGFBP3	-9275
PIK3R1	-9505
ATP6V1G2	-9515
NCBP2	-9558
ID3	-9614
RICTOR	-9670
MTOR	-9767
COL9A2	-9770
RAPGEF1	-9826
FLT3LG	-9894
LAMA2	-9911
WWP1	-10106
COL6A2	-10206
ITPR3	-10308
GRAP	-10321
CYFIP2	-10367
LRIG1	-10389
NAB2	-10400
ITGA3	-10750
ABI2	-10915
ID2	-10969
KIT	-11004
THEM4	-11069
WWOX	-11085
PLCG1	-11120
MXD4	-11285
PDE3B	-11322
NCK1	-11454
PDGFRB	-11545
ATP6V0E2	-11555
RPS6KA5	-11594
PRKCZ	-11629
FYN	-11675
STAT1	-11727
FGFRL1	-11778
FGFR2	-11785
LCK	-11838
AKT3	-11849
PRKACB	-11959
PRR5	-11985
PIK3R3	-12015
RALGDS	-12140
YES1	-12142
ATP6V0A2	-12211
FGFBP2	-12244
PDGFD	-12247
MATK	-12255
PTPRS	-12291
ERBB2	-12320
AXL	-12331
SH2D2A	-12359

---

Signaling by Interleukins

Signaling by Interleukins

	1104
set	Signaling by Interleukins
setSize	386
pANOVA	1.71e-19
s.dist	0.268
p.adjustANOVA	2.12e-17

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CSF2RA	9526
S100A12	9515
VAMP7	9499
SOCS3	9476
TALDO1	9456
CCR2	9449
CD36	9444
SERPINB2	9438
PRKACA	9429
ITGAM	9398
VIM	9394
IL1RN	9381
CA1	9380
PTAFR	9355
NKIRAS2	9353
MAOA	9346
LMNB1	9345
GRB2	9304
FPR1	9295
DUSP3	9280

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CSF2RA	9526.0
S100A12	9515.0
VAMP7	9499.0
SOCS3	9476.0
TALDO1	9456.0
CCR2	9449.0
CD36	9444.0
SERPINB2	9438.0
PRKACA	9429.0
ITGAM	9398.0
VIM	9394.0
IL1RN	9381.0
CA1	9380.0
PTAFR	9355.0
NKIRAS2	9353.0
MAOA	9346.0
LMNB1	9345.0
GRB2	9304.0
FPR1	9295.0
DUSP3	9280.0
IL10	9272.0
TNFRSF1A	9270.0
IL17RA	9194.0
IL1R2	9188.0
APP	9177.0
BCL6	9175.0
IL10RB	9163.0
IRAK3	9107.0
MAPK14	9104.0
GSTO1	9084.0
SYK	9076.0
ARF1	9064.0
MAP2K1	9063.0
PIK3CB	9038.0
STXBP2	9035.0
INPPL1	9028.0
ALOX5	9001.0
HCK	8976.0
MAPK3	8953.0
ITGB2	8942.0
IL1R1	8917.0
CRK	8906.0
MAP2K6	8887.0
F13A1	8876.0
CCR1	8865.0
HGF	8863.0
CEBPD	8816.0
RHOU	8794.0
MAP2K3	8748.0
BCL2L1	8700.0
CSF3R	8687.0
FOXO3	8682.0
TIMP1	8677.0
TOLLIP	8572.0
IRS2	8569.0
ANXA2	8544.0
STX3	8492.0
PSMB7	8485.0
MAP3K3	8471.0
NOD2	8442.0
P4HB	8440.0
PSMD4	8402.0
MAPKAPK3	8382.0
LCP1	8381.0
PELI2	8314.0
SOS2	8299.0
FN1	8284.0
HMOX1	8278.0
PSME3	8251.0
PPP2CA	8234.0
JAK3	8219.0
CFL1	8186.0
PAK2	8185.0
PTPN12	8151.0
MYD88	8136.0
CAPZA1	8135.0
IL6R	8132.0
PSMB5	8101.0
GAB2	8099.0
STAT3	8098.0
MEF2A	8009.0
CHUK	7966.0
PTK2B	7935.0
VAV1	7896.0
PSMD6	7846.0
ANXA1	7842.0
LYN	7809.0
FSCN1	7794.0
OSM	7780.0
LCN2	7755.0
PELI3	7716.0
PPP2CB	7712.0
PIM1	7704.0
RPS6KA1	7695.0
CSF2RB	7661.0
PSMD9	7620.0
PTPN2	7615.0
TEC	7549.0
CDC42	7537.0
MAPK1	7493.0
CBL	7480.0
VEGFA	7467.0
HIF1A	7436.0
PSMD2	7411.0
IL18	7381.0
IL4R	7358.0
ITGAX	7337.0
PSMA1	7329.0
PSMD1	7241.0
PSMB3	7171.0
IL1RAP	7150.0
MCL1	7133.0
IL27	7120.0
PSMA7	7096.0
TYK2	7087.0
PSMC1	7021.0
STAT5A	6965.0
TAB2	6964.0
STAT5B	6925.0
MMP1	6891.0
MAP2K4	6866.0
PITPNA	6820.0
PSMB6	6813.0
NFKBIA	6807.0
JUNB	6806.0
PRTN3	6762.0
IL19	6757.0
PELI1	6715.0
PTPN9	6712.0
ICAM1	6705.0
H3C15	6699.5
PSMF1	6659.0
CNN2	6645.0
UBB	6639.0
PSMC6	6635.0
MUC1	6573.0
PSMD12	6556.0
BATF	6386.0
NFKB1	6277.0
PSMD11	6231.0
FBXW11	6196.0
MAP3K8	6160.0
PTPN18	6149.0
IRAK1	6131.0
PTPN6	6096.0
PIK3CD	6046.0
TNFRSF1B	6045.0
PSMA6	5970.0
PSMD7	5963.0
PSMD13	5948.0
STAT6	5884.0
CXCL1	5824.0
PSMD8	5757.0
ATF1	5706.0
TAB1	5681.0
UBE2V1	5637.0
YWHAZ	5624.0
TNIP2	5552.0
CANX	5528.0
MSN	5524.0
FOS	5460.0
CXCL2	5412.0
IKBKG	5377.0
PSMA2	5339.0
IL13RA1	5336.0
PTPN11	5314.0
TGFB1	5153.0
CTSG	5115.0
PIK3R2	5010.0
CISH	4915.0
CNTF	4845.0
IL1B	4807.0
PTGS2	4753.0
SMARCA4	4733.0
HAVCR2	4630.0
PIK3CA	4629.0
PSMD3	4618.0
PPP2R1A	4589.0
CDKN1A	4511.0
UBC	4439.0
SOD2	4390.0
DUSP6	4357.0
SEM1	4348.0
MAPK10	4325.0
SKP1	4287.0
CTF1	4260.0
CASP1	4224.0
SHC1	4161.0
PSMB2	4084.0
SQSTM1	4081.0
MAPKAPK2	4054.0
IL6ST	4025.0
IL18R1	3994.0
NDN	3968.0
CRKL	3966.0
SOCS1	3947.0
RBX1	3934.0
HNRNPF	3929.0
FGF2	3920.0
EBI3	3833.0
MAPK11	3826.0
BIRC5	3738.0
JUN	3722.0
TCP1	3660.0
AKT1	3614.0
IL27RA	3441.0
PSMD5	3426.0
HNRNPA2B1	3380.0
PSMB1	3374.0
TBK1	3229.0
RAP1B	3206.0
SOCS5	3184.0
IL1RL1	3175.0
TAB3	3160.0
RPS6KA2	3087.0
LGALS9	3016.0
RPS6KA3	2973.0
POMC	2855.0
RALA	2710.0
JAK2	2691.0
PSMD14	2611.0
PSMC2	2598.0
IL15RA	2585.0
PSMB4	2523.0
COL1A2	2469.0
PPP2R5D	2421.0
MAP3K7	2395.0
MYC	2304.0
OPRM1	2161.0
ATF2	2085.0
HSP90B1	2059.0
NANOG	2038.0
PSMC3	1976.0
UBE2N	1936.0
IRS1	1741.0
CXCL8	1729.0
MMP9	1690.0
MAP2K7	1654.0
PSMD10	1559.0
POU2F1	1537.0
HSP90AA1	1326.0
AGER	1294.0
VRK3	1281.0
BOLA2	1257.0
UBA52	1121.0
ELK1	1040.0
RIPK2	1025.0
IL18RAP	823.0
STX4	606.0
IL33	445.0
CSF1R	394.0
NKIRAS1	375.0
IL17RC	193.0
CD86	-14.0
ITGB1	-94.0
NFKBIB	-152.0
TRAF6	-229.0
PPP2R1B	-241.0
HMGB1	-252.0
MEF2C	-293.0
PSMA4	-616.0
CASP3	-632.0
PSMC5	-863.0
RPLP0	-1000.0
NFKB2	-1165.0
PTPN23	-1186.0
MAPK7	-1337.0
CREB1	-1378.0
CRLF1	-1508.0
OSMR	-1577.0
RELA	-1803.0
TXLNA	-1846.0
CSF1	-2061.0
PTPN14	-2386.0
SOCS2	-2538.0
CCL3	-3027.0
PSMB8	-3076.0
DUSP7	-3211.0
LAMA5	-3263.0
AIP	-3566.0
PTPN20	-3783.0
MIF	-3863.0
INPP5D	-4038.0
STX1A	-4052.0
FCER2	-4230.0
BCL2	-4704.0
OPRD1	-4782.0
SOD1	-4862.0
BTRC	-4924.0
IL15	-5043.0
IGHE	-5123.0
PSMA3	-5285.0
IKBKB	-5386.0
CD4	-5406.0
IL17RE	-5421.0
S100B	-5457.0
SOS1	-5700.0
PSMB10	-5735.0
MTAP	-5790.0
PSMA5	-6053.0
PSME4	-6087.0
IGHG1	-6201.0
DUSP4	-6287.0
IL17RB	-6506.0
IL17C	-6641.0
PPIA	-6766.0
CD80	-6841.0
IGHG4	-6911.0
RPS27A	-6938.0
CCND1	-6970.0
MAPK9	-7068.0
IL2RA	-7161.0
BLNK	-7227.0
TNF	-7308.0
ZEB1	-7466.0
PSMA8	-7606.0
IL31RA	-7636.0
IL12A	-7823.0
CXCL10	-8160.0
IL7	-8554.0
RORC	-8573.0
IFNLR1	-8808.0
CCR5	-8861.0
IL20RB	-8921.0
IRF4	-8967.0
PSMC4	-9127.0
S1PR1	-9211.0
BRWD1	-9221.0
MAPK8	-9428.0
FOXO1	-9465.0
PIK3R1	-9505.0
IRAK2	-9548.0
IL16	-9726.0
IL11RA	-9753.0
HSPA9	-9780.0
RAPGEF1	-9826.0
PTPN13	-9962.0
PSME1	-9991.0
SNRPA1	-10023.0
IL32	-10122.0
IFNG	-10277.0
PSME2	-10336.0
IL4	-10399.0
IL23A	-10538.0
IL7R	-10546.0
IL18BP	-10561.0
IL10RA	-10594.0
STAT2	-10637.0
ALOX15	-10676.0
SIGIRR	-10752.0
PTPN7	-10868.0
TP53	-10893.0
HSPA8	-10922.0
JAK1	-10955.0
CCL5	-10985.0
IL24	-11009.0
CLCF1	-11150.0
IL5RA	-11211.0
HNRNPDL	-11232.0
PSMB9	-11324.0
CUL1	-11330.0
RAG1	-11432.0
RPS6KA5	-11594.0
FYN	-11675.0
STAT1	-11727.0
SMAD3	-11745.0
VAMP2	-11779.0
PDCD4	-11822.0
LCK	-11838.0
CCL4	-11976.0
RORA	-11979.0
IL12RB2	-11994.0
PIK3R3	-12015.0
IL2RG	-12050.0
IL3RA	-12057.0
IL12RB1	-12115.0
YES1	-12142.0
IL9R	-12179.0
GATA3	-12191.0
PTPN4	-12220.0
IL21R	-12256.0
NOD1	-12263.0
STAT4	-12336.0
CCL2	-12341.0
IL2RB	-12347.0
FASLG	-12371.0

---

Metabolism of proteins

Metabolism of proteins

	650
set	Metabolism of proteins
setSize	1718
pANOVA	2.21e-19
s.dist	0.131
p.adjustANOVA	2.52e-17

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CSF2RA	9526
ADAMTS2	9525
FAM20A	9524
PPARG	9522
CTSA	9514
VCAN	9505
NPL	9498
ASGR2	9487
F5	9485
BST1	9480
SOCS3	9476
RAB32	9463
RAB13	9440
CTSD	9433
FAM20C	9421
CPE	9420
FBXO9	9416
KIF13A	9413
FBXL5	9410
XRN2	9400

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CSF2RA	9526.0
ADAMTS2	9525.0
FAM20A	9524.0
PPARG	9522.0
CTSA	9514.0
VCAN	9505.0
NPL	9498.0
ASGR2	9487.0
F5	9485.0
BST1	9480.0
SOCS3	9476.0
RAB32	9463.0
RAB13	9440.0
CTSD	9433.0
FAM20C	9421.0
CPE	9420.0
FBXO9	9416.0
KIF13A	9413.0
FBXL5	9410.0
XRN2	9400.0
LAMC1	9387.0
CKAP4	9370.0
RHOT1	9367.0
RAB31	9356.0
SNCA	9354.0
ANPEP	9350.0
GNG10	9349.0
APLP2	9347.0
SNX3	9326.0
QSOX1	9298.0
FSTL3	9290.0
H2BC21	9283.0
TPST1	9251.0
MSRB1	9247.0
ATP6V0D1	9245.0
ASGR1	9212.0
PCSK9	9208.0
RAB3D	9207.0
UIMC1	9202.0
MITF	9193.0
CES1	9192.0
ARF4	9191.0
UBE2D1	9187.0
NCSTN	9186.0
APP	9177.0
KLHL2	9174.0
SERPINA1	9168.0
DCTN2	9157.0
SPTB	9154.0
VNN2	9153.0
CD55	9145.0
KDELR1	9142.0
ST6GALNAC3	9134.0
VNN1	9092.0
FURIN	9075.0
MSRB2	9067.0
ARF1	9064.0
RAB1A	9052.0
H2BC12	9051.0
PHC2	9043.0
LGALS1	9032.0
NEU1	9029.0
ACTB	9011.0
SUMF1	8991.0
CTSZ	8975.0
GBA	8969.0
HDAC4	8960.0
ALPL	8947.0
B3GNT8	8945.0
ERO1A	8943.0
PNPLA2	8939.0
TPP1	8936.0
RAB10	8926.0
NLRP3	8901.0
OS9	8898.0
TGFA	8889.0
RAD23B	8886.0
NUCB1	8883.0
IGFBP2	8856.0
GALNT14	8844.0
GALNT2	8843.0
CMAS	8839.0
B4GALT5	8830.0
NSF	8829.0
NUP58	8820.0
GNG5	8815.0
ADAM10	8791.0
ADAMTS3	8785.0
PCMT1	8779.0
ANK1	8771.0
EXOC6	8762.0
GSN	8749.0
RAB7A	8742.0
GLB1	8725.0
TGOLN2	8714.0
EDEM2	8704.0
USP3	8699.0
RNF146	8696.0
RAB11A	8688.0
TIMP1	8677.0
MGAT4B	8675.0
ST3GAL2	8669.0
B3GNT5	8666.0
H3-3A	8661.0
TUBB2A	8659.0
RAB5C	8655.0
UBE2D3	8640.0
FBXL19	8620.0
CDC34	8611.0
RAB2A	8604.0
CAPZA2	8597.0
FKBP8	8579.0
SIAH2	8578.0
NRN1	8565.0
SOCS6	8557.0
RNF135	8556.0
UBE2R2	8548.0
SERP1	8543.0
EDEM3	8538.0
TLN1	8525.0
SMAD1	8511.0
ARRB2	8490.0
PSMB7	8485.0
FKBP9	8475.0
ATF6	8464.0
PTEN	8460.0
NOD2	8442.0
P4HB	8440.0
ADORA2B	8437.0
DNAJC3	8435.0
PLAUR	8424.0
RAB34	8420.0
RAB27A	8411.0
PSMD4	8402.0
DCTN4	8387.0
GCNT1	8379.0
TNIP1	8378.0
COPA	8366.0
RAB20	8351.0
MRTFA	8350.0
VDR	8348.0
DCAF6	8336.0
AGTPBP1	8330.0
RHOA	8319.0
RAB1B	8313.0
FUCA2	8304.0
GNB1	8294.0
ACADVL	8290.0
TXN	8285.0
FN1	8284.0
UBE2J2	8268.0
PSME3	8251.0
KIF5B	8239.0
ST8SIA4	8236.0
TRIM25	8226.0
GALNT7	8224.0
RAB40C	8215.0
TGFBI	8211.0
C1GALT1C1	8153.0
RAB6A	8148.0
TRIM27	8142.0
GNB2	8141.0
CAPZA1	8135.0
RAB3A	8133.0
SEC24D	8115.0
PSMB5	8101.0
STAT3	8098.0
ANKRD9	8085.0
GNAI2	8075.0
GAS6	8063.0
ATP6AP2	8034.0
EIF4G1	8031.0
RPN1	8024.0
CAPZB	8015.0
H2BC5	8003.0
CEBPB	7997.0
NCOR2	7985.0
COMMD9	7967.0
LTBP1	7962.0
NANS	7957.0
GNAI3	7953.0
TMED7	7950.0
RAB4A	7941.0
H2AC6	7934.0
JOSD2	7931.0
UBE2W	7929.0
MAN1A1	7927.0
NUP214	7921.0
SEC11A	7920.0
RNF7	7913.0
H2BC11	7912.0
FSTL1	7908.0
COPB2	7902.0
TTLL4	7901.0
CALU	7894.0
EPAS1	7886.0
ARF5	7885.0
NUS1	7864.0
WSB1	7862.0
VDAC2	7857.0
PSMD6	7846.0
DPH3	7837.0
USP4	7812.0
TRAPPC1	7806.0
RAB18	7801.0
CNIH1	7779.0
UBA3	7767.0
GSK3A	7760.0
PROS1	7758.0
MPDU1	7751.0
EIF4H	7750.0
WSB2	7743.0
DYNC1I2	7735.0
ARF3	7732.0
KDELR2	7728.0
ETFB	7688.0
UBE2H	7663.0
CSF2RB	7661.0
SEC24A	7660.0
SPHK1	7657.0
NFYC	7653.0
TOP1	7645.0
MBD6	7623.0
PSMD9	7620.0
ACTR10	7605.0
EXOSC4	7600.0
SPTA1	7595.0
COPG2	7594.0
EIF4A1	7590.0
PDIA5	7581.0
ARSB	7572.0
UBE2L3	7561.0
H2BC18	7547.0
USP10	7542.0
YOD1	7533.0
ADAMTSL4	7530.0
HNRNPK	7522.0
ELOC	7519.0
LRRC41	7515.0
H2AC11	7513.0
MRPL28	7510.0
COPG1	7509.0
PGA3	7501.0
FBXO7	7498.0
RXRA	7495.0
ELOB	7482.0
PGA5	7478.0
UBE2M	7477.0
CFP	7445.0
HIF1A	7436.0
ETF1	7419.0
NR1H2	7415.0
PSMD2	7411.0
FUCA1	7408.0
H2BC4	7389.0
MSRA	7382.0
ARSD	7365.0
AMFR	7363.0
PIAS1	7361.0
TADA3	7356.0
COMMD8	7353.0
UBE2F	7341.0
GNB4	7336.0
SEC23A	7335.0
PSMA1	7329.0
COPB1	7321.0
TUBA1A	7313.0
UBE2A	7309.0
MYDGF	7308.0
DCTN6	7300.0
CARS1	7297.0
H2BC17	7285.0
WIPI1	7277.0
RAB33B	7267.0
FPGT	7264.0
HDGF	7262.0
PSMD1	7241.0
TUBB4B	7240.0
SLC35A1	7225.0
CCT5	7220.0
MRPS36	7215.0
LYZ	7213.0
TUBA1C	7198.0
MELTF	7197.0
CARS2	7177.0
RPL26L1	7176.0
PSMB3	7171.0
TMED9	7167.0
STX5	7166.0
TFG	7160.0
RPN2	7140.0
CHCHD1	7129.0
MAVS	7124.0
TRAPPC3	7114.0
RAB39A	7113.0
TAF10	7110.0
RAB5A	7103.0
MCFD2	7099.0
PSMA7	7096.0
RAB14	7095.0
UBA1	7089.0
LMAN2	7080.0
HERPUD1	7077.0
GALNT4	7072.0
IDE	7051.0
CPM	7044.0
SUMO3	7042.0
PIGS	7033.0
HSPA5	7029.0
F8	7022.0
PSMC1	7021.0
SEC61B	7013.0
UBE2B	7003.0
ACTR1A	7002.0
MRPL23	6995.0
MRPL33	6993.0
GARS1	6990.0
TSPAN14	6971.0
TADA2B	6952.0
DYNC1LI1	6941.0
LMAN2L	6937.0
TUBA8	6933.0
DDOST	6931.0
RTN4RL2	6898.0
COPE	6896.0
MMP1	6891.0
SUMO1	6889.0
VCP	6886.0
UBE2K	6884.0
SEL1L	6847.0
PGA4	6836.0
CUL3	6821.0
PPP6C	6819.0
PSMB6	6813.0
NFKBIA	6807.0
DCP2	6804.0
RNF123	6802.0
SATB2	6781.0
WDTC1	6779.0
PPP2R5B	6774.0
UBE2E1	6759.0
XRCC4	6758.0
EIF2S3	6747.0
ST6GALNAC2	6746.0
ST3GAL6	6701.0
H3C15	6699.5
FBXO11	6698.0
MYO5A	6693.0
RAB5B	6690.0
GNAT2	6683.0
TDG	6672.0
PSMF1	6659.0
USP22	6652.0
MSRB3	6649.0
UBB	6639.0
PSMC6	6635.0
RNF40	6628.0
MAN2A2	6625.0
GORASP1	6606.0
PIGF	6597.0
SRP54	6591.0
COPS7A	6590.0
SSR1	6588.0
RENBP	6585.0
MUC1	6573.0
FBXW2	6560.0
PSMD12	6556.0
CCT8	6552.0
IGFBP7	6545.0
CCDC22	6533.0
SORL1	6530.0
RAB8B	6529.0
DCUN1D1	6523.0
BECN1	6516.0
RAD23A	6512.0
GALNT1	6508.0
GNG11	6495.0
RNF185	6491.0
TUBA4A	6484.0
NEDD8	6482.0
SAR1B	6479.0
GSPT1	6475.0
SEC61A1	6449.0
RAB43	6433.0
RARA	6429.0
PARK7	6421.0
USP8	6418.0
CTNNB1	6408.0
FOXO4	6391.0
CSNK2A2	6388.0
KBTBD7	6376.0
PREB	6368.0
CTSH	6360.0
CALR	6340.0
USP7	6323.0
SRP14	6320.0
LTF	6306.0
COL7A1	6304.0
APH1B	6280.0
TTLL7	6266.0
MGAT1	6257.0
BRCA1	6248.0
RRAGA	6244.0
TSTA3	6241.0
INO80C	6240.0
HNRNPC	6239.0
ATF4	6237.0
PSMD11	6231.0
ASB7	6221.0
GOLGA2	6203.0
CSNK2A1	6199.0
FBXW11	6196.0
EIF2S2	6175.0
TSPAN33	6170.0
RAB21	6165.0
STAM2	6159.0
USP15	6148.0
BRCC3	6145.0
COPS2	6139.0
EP300	6129.0
HDAC7	6122.0
ANO8	6099.0
RGS6	6086.0
HIPK2	6078.0
AURKAIP1	6074.0
EIF4EBP1	6072.0
NSMCE1	6056.0
RAB6B	6053.0
TMED2	6052.0
H2AZ1	6036.0
RNF181	6022.0
ZBED1	6017.0
COPS3	6005.0
DCTN3	5994.0
GPAA1	5992.0
ITM2B	5982.0
AREG	5977.0
PSMA6	5970.0
MRPL53	5968.0
LAMB1	5966.0
P2RY2	5965.0
PSMD7	5963.0
VNN3	5958.0
DYNLL1	5952.0
THBS1	5951.0
PSMD13	5948.0
SSR3	5935.0
CHST8	5900.0
DAD1	5895.0
PDIA6	5882.0
APOA2	5879.0
SEC22B	5873.0
COMMD1	5871.0
B3GNT2	5868.0
NSMCE2	5864.0
CD59	5859.0
BCL10	5849.0
IARS2	5821.0
ST3GAL4	5781.0
PSMD8	5757.0
SEC13	5748.0
ALG14	5746.0
PSENEN	5735.0
RNF20	5727.0
TPST2	5725.0
ADD1	5704.0
DNAJB11	5691.0
TUBB6	5685.0
TAB1	5681.0
EXOC1	5670.0
CETN2	5642.0
RAB36	5636.0
NTNG2	5601.0
EXOC4	5591.0
CTDSP2	5586.0
ARCN1	5580.0
OXA1L	5578.0
MIA2	5574.0
EXTL3	5561.0
TNIP2	5552.0
FBXL13	5534.0
CANX	5528.0
B3GNTL1	5520.0
TUBA1B	5509.0
TMEM115	5508.0
COMMD5	5497.0
FBXL4	5496.0
SP3	5490.0
TUBB1	5488.0
HDAC2	5482.0
AP3M1	5469.0
CEBPG	5466.0
USP9X	5464.0
CBX8	5448.0
RPS9	5421.0
NARS1	5415.0
PIGX	5399.0
SDC2	5397.0
H2BC9	5394.0
IKBKG	5377.0
RAB24	5354.0
TTLL12	5353.0
PABPC1	5351.0
MRPL30	5347.0
PSMA2	5339.0
TRAPPC9	5333.0
H2BC15	5312.0
TFPT	5309.0
STAG2	5301.0
WAC	5267.0
PPP6R1	5263.0
ZDHHC2	5254.0
TMEM132A	5245.0
VBP1	5239.0
GGCX	5237.0
TBCA	5235.0
COMMD7	5226.0
PRKCSH	5220.0
YKT6	5205.0
TRAPPC5	5191.0
PIAS4	5184.0
RAE1	5164.0
FEM1C	5160.0
METTL22	5157.0
TGFB1	5153.0
MTRF1L	5149.0
CCNE2	5143.0
CTSG	5115.0
KLHL5	5105.0
UBE2C	5101.0
UGGT1	5082.0
DCTN1	5078.0
KDM1B	5073.0
SRPRA	5058.0
KLHL21	5054.0
CDC73	5020.0
UBE2E3	5005.0
GCNT3	4996.0
SLC17A5	4989.0
USP12	4974.0
H2AC20	4972.0
SUMO2	4961.0
GMDS	4937.0
EXOC7	4924.0
DCAF10	4922.0
UBE2G1	4921.0
CISH	4915.0
DDIT3	4906.0
SMAD2	4905.0
KEAP1	4898.0
UGGT2	4897.0
ASB8	4884.0
MRPS5	4861.0
MRPL51	4848.0
FBXL20	4844.0
AR	4840.0
FBN1	4836.0
EIF4E	4813.0
MRPS10	4810.0
UBE2S	4746.0
AOPEP	4739.0
EIF3H	4729.0
EXOC3	4724.0
DPM2	4721.0
IKBKE	4715.0
SEC61G	4708.0
EIF3I	4700.0
BIRC2	4692.0
FBXO30	4683.0
HDAC3	4673.0
UBE2D2	4657.0
SEC16A	4619.0
PSMD3	4618.0
NRIP1	4609.0
PTRH2	4601.0
EIF3M	4580.0
MRPL44	4552.0
SUDS3	4526.0
NUP50	4521.0
HGS	4513.0
RPL3L	4503.0
FBXL15	4499.0
TUFM	4494.0
NCOA1	4483.0
C4A	4466.0
STS	4459.0
MRPS16	4452.0
SRP9	4444.0
UBC	4439.0
TPGS1	4435.0
FEM1B	4426.0
ING2	4415.0
RAB11B	4402.0
USP48	4399.0
KLHDC3	4392.0
KCTD6	4371.0
SPCS3	4370.0
COPS5	4361.0
SEM1	4348.0
VDAC1	4347.0
DCUN1D3	4333.0
CD109	4316.0
SP100	4314.0
FCGR3B	4313.0
MDM2	4312.0
RFT1	4309.0
RAB19	4300.0
GNG8	4296.0
DNMT3B	4294.0
B4GALT1	4292.0
SKP1	4287.0
SRP19	4280.0
EIF2S1	4279.0
COMMD10	4274.0
DYNC1LI2	4273.0
COG7	4269.0
HCFC1	4254.0
PEX5	4225.0
DYNC1I1	4187.0
PMM1	4176.0
SHC1	4161.0
USO1	4154.0
TRAPPC6B	4147.0
EXOC5	4141.0
NAPG	4139.0
APH1A	4133.0
PDIA3	4128.0
STT3A	4095.0
RAB9A	4088.0
PSMB2	4084.0
SULT1A3	4082.0
MRPL47	4077.0
MRPL58	4049.0
COPZ1	4035.0
SENP2	4030.0
FBXL8	4021.0
CDC20	3998.0
PPARGC1A	3988.0
RAB35	3981.0
SRD5A3	3971.0
CSNK2B	3969.0
TMEM129	3961.0
ADRM1	3953.0
RBX1	3934.0
RAB42	3932.0
TGFBR2	3914.0
GFM2	3905.0
SERPINA10	3902.0
LMNA	3887.0
GMPPA	3886.0
RAB8A	3880.0
OTOA	3867.0
MRPS34	3820.0
GGA3	3816.0
FN3K	3813.0
BIRC5	3738.0
ZRANB1	3730.0
ARFGAP3	3714.0
MRPL52	3707.0
VHL	3674.0
ALB	3668.0
PFDN5	3664.0
TCP1	3660.0
CLSPN	3640.0
BACE1	3609.0
SEC24B	3608.0
PFDN1	3598.0
PIGB	3580.0
MFGE8	3534.0
RTF1	3526.0
SCFD1	3525.0
KIN	3521.0
AGBL5	3518.0
RNF2	3513.0
METTL21A	3509.0
NFYA	3506.0
ARSA	3486.0
PAF1	3478.0
FBXO17	3474.0
MTFMT	3460.0
UBA6	3438.0
PSMD5	3426.0
CREBBP	3423.0
FFAR4	3410.0
RAB27B	3386.0
PSMB1	3374.0
KTN1	3363.0
FOXK2	3358.0
CTR9	3344.0
AURKA	3330.0
GNAI1	3329.0
ASB13	3324.0
ASB1	3319.0
FBXL18	3309.0
ADORA2A	3293.0
RNF152	3269.0
PPP6R3	3261.0
EIF2B2	3260.0
TUBB3	3242.0
APC	3240.0
INHBA	3227.0
SPCS2	3211.0
MRPL37	3208.0
COMMD2	3198.0
SOCS5	3184.0
NAGK	3158.0
ERCC8	3154.0
RAB4B	3137.0
SSR4	3135.0
DDA1	3127.0
PEX14	3125.0
MRPL13	3120.0
NUP98	3101.0
SENP8	3086.0
NUP37	3074.0
DDB1	3060.0
DERL2	3041.0
KLK2	3029.0
PIGZ	3026.0
SPCS1	3021.0
MBTPS1	2966.0
MUL1	2961.0
PEX2	2946.0
TARS1	2926.0
CDC25A	2911.0
GNAZ	2909.0
UBE2V2	2902.0
DOLPP1	2858.0
POMC	2855.0
TOPORS	2830.0
SSR2	2818.0
CUL4B	2802.0
MRPS35	2793.0
MTIF3	2791.0
TOP2A	2778.0
MRPS24	2777.0
TBCB	2776.0
ETFBKMT	2766.0
MRPS7	2753.0
SLC35C1	2750.0
MRPL45	2735.0
KBTBD6	2724.0
TMED3	2720.0
KHSRP	2714.0
EIF2B4	2707.0
SEMA5B	2706.0
ALG12	2659.0
RNF139	2627.0
EIF3D	2624.0
SAFB	2615.0
MAGT1	2613.0
USP49	2612.0
PSMD14	2611.0
PSMC2	2598.0
MBD5	2592.0
EIF3L	2579.0
DPM3	2577.0
PTP4A2	2561.0
MRPL12	2529.0
GCNT7	2527.0
CUL2	2526.0
PSMB4	2523.0
CFTR	2416.0
MAP3K7	2395.0
CSNK1D	2390.0
SPSB1	2374.0
FBXO40	2368.0
CTSC	2326.0
MLEC	2322.0
GGA1	2310.0
MYC	2304.0
CHM	2273.0
ADRA2A	2271.0
BTBD1	2263.0
CBX4	2222.0
CST3	2206.0
EIF5	2175.0
DPAGT1	2163.0
EIF3A	2145.0
MRPL18	2144.0
IGFBP6	2143.0
MT-RNR2	2112.0
PPA2	2096.0
RPS27L	2061.0
HSP90B1	2059.0
CCP110	2050.0
MRPL16	2042.0
MRPL36	2032.0
MBD1	2028.0
SRP68	2014.0
ARRB1	1998.0
PSMC3	1976.0
TUBA4B	1967.0
UCHL3	1959.0
LSAMP	1958.0
FCSK	1950.0
FEM1A	1947.0
UBE2N	1936.0
PPA1	1934.0
EIF3E	1915.0
EIF3J	1898.0
UBXN1	1892.0
FARSA	1876.0
ASXL2	1856.0
PIGN	1847.0
GALNT3	1805.0
MRPS22	1788.0
PIGQ	1782.0
COPS4	1776.0
MRPL22	1773.0
ZBTB17	1763.0
SFTPB	1754.0
CXCL8	1729.0
RAD21	1709.0
MRPS23	1699.0
GADD45GIP1	1697.0
PRMT3	1695.0
CCNA2	1685.0
ST8SIA5	1668.0
ALG6	1653.0
COPS6	1637.0
MGAT2	1633.0
STAMBP	1611.0
ATXN3	1601.0
ASB9	1587.0
TGFBR1	1585.0
DPM1	1567.0
PSMD10	1559.0
UBXN7	1556.0
CDK1	1540.0
KIFC3	1513.0
MRPS15	1487.0
EIF3K	1478.0
MRPS28	1464.0
NEGR1	1459.0
TSFM	1444.0
NAPA	1432.0
THRB	1429.0
MRPL15	1403.0
CCDC8	1402.0
OTUB1	1400.0
PMM2	1394.0
MRPS11	1391.0
KLHL9	1353.0
RTN4RL1	1345.0
ASB3	1325.0
STAM	1285.0
SHISA5	1269.0
SLC34A2	1253.0
EIF4B	1247.0
PFDN4	1163.0
BAP1	1126.0
UBA52	1121.0
TF	1102.0
SEC31A	1099.0
NCOA2	1092.0
PFDN2	1091.0
EIF1AX	1090.0
B4GALNT2	1079.0
DARS1	1069.0
RAB23	1046.0
RBBP5	1037.0
TSPAN5	1028.0
RIPK2	1025.0
FBXL3	1005.0
APEH	997.0
SYVN1	992.0
EIF3F	977.0
PIGT	952.0
MME	916.0
GNG3	890.0
EIF3G	878.0
GNAT1	877.0
DCUN1D5	861.0
USP30	856.0
ADAMTSL3	855.0
AURKB	846.0
CUL5	834.0
DNAJB9	820.0
PPARA	813.0
MRPL21	810.0
GALNT16	790.0
NUP62	769.0
MRPS18A	744.0
TRMT112	738.0
KLHL13	702.0
ZBTB16	689.0
CNIH2	654.0
HLA-B	649.0
POMT2	624.0
SMC1A	613.0
HDAC1	587.0
CCNA1	585.0
RAB44	573.0
PEX13	571.0
EIF5A	553.0
CAMKMT	550.0
YY1	537.0
CCT4	531.0
DHPS	525.0
GNB5	512.0
NR3C1	511.0
EXOSC3	509.0
ST3GAL3	505.0
LAMB2	501.0
MRPL19	452.0
IL33	445.0
VDAC3	436.0
DTL	428.0
RPS4Y1	424.0
B4GALT4	391.0
VCPKMT	334.0
SEC16B	330.0
TMED10	323.0
DPH5	315.0
EEF2	306.0
EIF3C	287.0
FBXW5	265.0
JOSD1	227.0
APOE	218.0
GALNT15	190.0
MRPS18C	181.0
USP25	173.0
KLF4	157.0
WDR5	155.0
QARS1	86.0
MBTPS2	83.0
WDR61	77.0
PIGM	62.0
LEO1	39.0
RPL36AL	32.0
RPLP1	19.0
EXOC8	-1.0
SLC30A6	-3.0
COG4	-6.0
TBC1D20	-18.0
B3GALNT2	-28.0
HYOU1	-113.0
EDEM1	-114.0
GOSR1	-182.0
CREBRF	-188.0
YIF1A	-225.0
TRAF6	-229.0
RWDD3	-238.0
RPS24	-263.0
VCPIP1	-268.0
MT-RNR1	-300.0
TTF1	-328.0
COG8	-346.0
FAU	-362.0
MRPL20	-411.0
EIF2B1	-414.0
USP19	-456.0
SEC23IP	-468.0
TNKS2	-499.0
ARL2	-565.0
PRSS21	-577.0
NPPA	-584.0
BET1	-594.0
PSMA4	-616.0
ST6GALNAC4	-629.0
CCT6A	-642.0
FBXO41	-657.0
OTULIN	-683.0
MANEA	-699.0
ALG5	-708.0
UBE2I	-764.0
ICMT	-786.0
RARS2	-790.0
GALNT6	-806.0
MTIF2	-809.0
EEF1D	-811.0
RANBP2	-820.0
USP33	-821.0
RAB12	-856.0
PSMC5	-863.0
BABAM1	-897.0
PGM3	-906.0
USP34	-944.0
RPL15	-963.0
OTUB2	-980.0
GANAB	-986.0
AIMP2	-988.0
MRPL3	-990.0
EXOSC1	-991.0
RPLP0	-1000.0
MRPL34	-1004.0
RAD52	-1021.0
WDR20	-1033.0
COMMD6	-1053.0
CREB3L2	-1143.0
GALNT5	-1162.0
NFKB2	-1165.0
TTLL2	-1171.0
RPL8	-1187.0
MDM4	-1230.0
ALG2	-1259.0
ALG3	-1263.0
FBXO15	-1269.0
DAP3	-1301.0
FBXL12	-1321.0
PDCL	-1328.0
MRPL41	-1345.0
MAN2A1	-1349.0
PIAS3	-1358.0
COMMD3	-1363.0
EEF1G	-1383.0
GAN	-1414.0
RPS26	-1430.0
GOSR2	-1456.0
PIGC	-1461.0
RPL28	-1462.0
BGLAP	-1473.0
SRP72	-1491.0
CHML	-1515.0
RAB7B	-1531.0
MRPL57	-1540.0
ST6GAL2	-1541.0
CP	-1561.0
XBP1	-1579.0
NR4A2	-1601.0
SLC34A1	-1602.0
RPL22L1	-1619.0
DOHH	-1655.0
DCAF7	-1721.0
RPS13	-1749.0
RELA	-1803.0
PIGV	-1810.0
NICN1	-1831.0
CDCA8	-1838.0
RPL9	-1872.0
TSPAN15	-1876.0
MRPL4	-1883.0
POMK	-1918.0
EEF1A1P5	-1925.0
SELENOS	-1930.0
ARFGAP1	-1942.0
INO80B	-1954.0
RPL7	-1955.0
MRPL54	-1962.0
SMC3	-1975.0
PLG	-1977.0
ATXN7	-1983.0
PUM2	-2007.0
MAN1A2	-2055.0
CSF1	-2061.0
EEF1E1	-2072.0
CALM1	-2081.0
RPS8	-2083.0
MGAT4C	-2109.0
KDELR3	-2117.0
GNG4	-2154.0
CXXC1	-2167.0
ASB14	-2170.0
MSLN	-2192.0
MUCL1	-2211.0
DHDDS	-2236.0
PFDN6	-2247.0
TRIM13	-2263.0
TRAPPC2L	-2299.0
FBXO6	-2300.0
TTLL3	-2342.0
ENAM	-2373.0
MGAT3	-2391.0
GNB3	-2397.0
CCT3	-2404.0
SUZ12	-2409.0
KAT2B	-2414.0
DCAF11	-2444.0
SLC30A5	-2461.0
RABGGTA	-2462.0
MRPL43	-2517.0
HIF3A	-2519.0
SOCS2	-2538.0
CD52	-2561.0
SEC24C	-2569.0
HLA-A	-2573.0
MARS1	-2588.0
TAF9B	-2599.0
MRPL14	-2647.0
RAB3B	-2698.0
SERPIND1	-2722.0
TOP2B	-2731.0
TOMM20	-2743.0
MRPL48	-2762.0
ASB6	-2763.0
NAPB	-2780.0
CALB1	-2832.0
RPL27	-2855.0
NFRKB	-2874.0
MUC6	-2977.0
SIAH1	-3000.0
MTA1	-3005.0
RPL39	-3006.0
B3GNT9	-3033.0
DNMT3A	-3039.0
NUP85	-3049.0
MOGS	-3051.0
MGAT5	-3072.0
MRPL27	-3073.0
PSMB8	-3076.0
NEURL2	-3097.0
CCT7	-3100.0
GALNT11	-3148.0
TPGS2	-3167.0
EPRS1	-3185.0
MUC4	-3191.0
COG5	-3259.0
RPL23	-3314.0
CUL7	-3334.0
TBCE	-3336.0
GALNT10	-3341.0
RPL6	-3354.0
OBSL1	-3404.0
SKIV2L	-3414.0
BARD1	-3419.0
RPL13	-3431.0
ADAMTS5	-3479.0
ZNF350	-3507.0
SPTBN5	-3531.0
THSD4	-3560.0
RPL4	-3582.0
DARS2	-3589.0
ALG11	-3593.0
NR1H3	-3597.0
RPL29	-3611.0
MRPS12	-3618.0
ALG8	-3635.0
DOLK	-3639.0
MT-TV	-3652.0
RPL7A	-3665.0
RPS15	-3673.0
MARCHF6	-3678.0
NGLY1	-3686.0
FBXO22	-3709.0
PAPPA	-3791.0
ADAMTS17	-3827.0
NEU3	-3833.0
PROZ	-3872.0
CCDC59	-3900.0
NAT8B	-3939.0
RPL37A	-3946.0
MRPL11	-3948.0
USP47	-3954.0
RAB41	-3974.0
DYNLL2	-3980.0
B3GNT3	-4017.0
SPSB2	-4034.0
TNC	-4039.0
STX1A	-4052.0
RING1	-4063.0
TULP4	-4065.0
RPS21	-4079.0
BMP4	-4081.0
DCTN5	-4086.0
MUC16	-4104.0
POMGNT2	-4115.0
TTLL5	-4116.0
PCGF2	-4135.0
TTL	-4136.0
YARS2	-4147.0
NAPSA	-4183.0
RAB22A	-4208.0
KBTBD8	-4224.0
SEC22C	-4248.0
ARFGEF2	-4255.0
CREB3	-4257.0
EEF1B2	-4261.0
SMC6	-4277.0
UCN	-4278.0
MDGA1	-4285.0
GBF1	-4290.0
C1GALT1	-4297.0
DIS3	-4322.0
RNF168	-4331.0
ADAMTS13	-4374.0
NR1I2	-4435.0
RAB26	-4448.0
SLC30A7	-4455.0
RPS2	-4499.0
GPS1	-4517.0
RNF103	-4536.0
RPL31	-4541.0
EXOSC5	-4577.0
MRPL35	-4593.0
MUC5B	-4613.0
CBX2	-4617.0
COMMD4	-4618.0
ERAL1	-4628.0
TRAM1	-4636.0
EIF5B	-4637.0
RPS16	-4669.0
RCE1	-4674.0
BLM	-4690.0
RPS3A	-4694.0
RPS28	-4713.0
RPL5	-4728.0
RPL22	-4740.0
ARSG	-4773.0
LARGE2	-4786.0
RARS1	-4794.0
WARS2	-4809.0
CUL4A	-4810.0
DCUN1D2	-4811.0
MAN1B1	-4871.0
ACTR8	-4894.0
ANK3	-4919.0
BTRC	-4924.0
MRPS31	-4932.0
MRPS14	-4958.0
RPS7	-4968.0
SEC22A	-5052.0
TRIM28	-5056.0
FOXK1	-5059.0
FBXO27	-5074.0
RPL18	-5080.0
EEF1A1	-5087.0
CRHR2	-5119.0
SPTBN2	-5129.0
OTUD5	-5132.0
EEF1A2	-5166.0
PIGP	-5179.0
FUOM	-5190.0
GNE	-5192.0
GNG7	-5198.0
BTBD6	-5202.0
PARN	-5224.0
INO80D	-5234.0
CDKN2A	-5236.0
RABGGTB	-5240.0
USP14	-5246.0
TTLL11	-5257.0
TECTA	-5268.0
PSMA3	-5285.0
GFM1	-5286.0
RPL36	-5287.0
ST6GALNAC1	-5314.0
FOLR2	-5337.0
GOLGB1	-5370.0
KARS1	-5382.0
COG3	-5426.0
RPL17	-5431.0
RPS14	-5463.0
RAB15	-5520.0
ARSJ	-5542.0
NUP42	-5564.0
DCAF13	-5572.0
TRAF3	-5576.0
ASB4	-5604.0
MRPS17	-5606.0
PLA2G7	-5617.0
B4GAT1	-5642.0
MRPL1	-5678.0
MGAT4A	-5680.0
MRPL40	-5682.0
RPS5	-5691.0
PSMB10	-5735.0
RPS15A	-5742.0
LONP2	-5755.0
ARFGAP2	-5786.0
RPS10	-5793.0
RPL24	-5799.0
COG6	-5811.0
SCMH1	-5839.0
RPL38	-5840.0
MVD	-5850.0
MRPL55	-5885.0
AIMP1	-5902.0
SARS1	-5909.0
LARGE1	-5910.0
RPS3	-5914.0
INCENP	-5956.0
MUC20	-5962.0
PCNA	-5969.0
RPS12	-5987.0
YARS1	-5991.0
PIGK	-5994.0
RPL35A	-6015.0
SPSB3	-6020.0
B4GALT2	-6034.0
PSMA5	-6053.0
USP5	-6068.0
SEH1L	-6069.0
RPL18A	-6070.0
PSME4	-6087.0
NUDT14	-6100.0
CUL9	-6106.0
VARS2	-6119.0
FBXL14	-6145.0
RPS6	-6160.0
TCF7L2	-6185.0
ACE	-6215.0
DDX11	-6222.0
MRPS26	-6240.0
MIA3	-6245.0
RPS17	-6247.0
ANKRD28	-6250.0
RPL27A	-6257.0
RPL11	-6261.0
DDX17	-6274.0
RPL19	-6281.0
RPS4X	-6285.0
KLHL11	-6286.0
RPS23	-6292.0
MRPL24	-6300.0
NUP153	-6321.0
RPSA	-6323.0
STAG1	-6347.0
RPS25	-6365.0
RPL37	-6375.0
LYPD5	-6380.0
THRA	-6387.0
RNF5	-6413.0
FBXO10	-6427.0
LARS1	-6428.0
CTBP1	-6456.0
RPL21	-6458.0
GFPT1	-6462.0
UBA2	-6489.0
RPL10	-6534.0
RAB9B	-6552.0
CAND1	-6554.0
H2BU1	-6555.0
PEX10	-6570.0
GGA2	-6587.0
MRPL38	-6596.0
FBXW7	-6600.0
RPL26	-6612.0
FGF23	-6622.0
PARS2	-6637.0
FBXL16	-6648.0
ASB16	-6665.0
PLA2G4B	-6679.0
RPL10A	-6686.0
SENP5	-6689.0
RPL32	-6709.0
RPL14	-6710.0
TRAPPC4	-6712.0
ADAMTS14	-6719.0
TRRAP	-6722.0
USP13	-6737.0
RPL34	-6802.0
MAN1C1	-6804.0
ITIH2	-6820.0
GOLM1	-6842.0
MRPS2	-6844.0
RPL41	-6866.0
B2M	-6920.0
RPS27A	-6938.0
RPS19	-6965.0
USP21	-6972.0
RPL30	-7020.0
TPR	-7028.0
RPL12	-7053.0
ADAMTS6	-7055.0
SMC5	-7084.0
RPLP2	-7087.0
OGT	-7119.0
DPP4	-7125.0
CPA3	-7164.0
POM121C	-7188.0
PIGA	-7195.0
RPS11	-7243.0
MRPL2	-7263.0
THSD1	-7288.0
LYPD3	-7315.0
VARS1	-7323.0
GMPPB	-7332.0
FBXW9	-7360.0
RPL36A	-7376.0
DAG1	-7379.0
MYSM1	-7386.0
BET1L	-7405.0
ST3GAL1	-7442.0
MRPL42	-7464.0
ACTL6A	-7468.0
MXRA8	-7477.0
PIAS2	-7496.0
GPLD1	-7524.0
POLB	-7537.0
NRN1L	-7549.0
ENGASE	-7552.0
WARS1	-7572.0
IGFBP4	-7582.0
PSMA8	-7606.0
TTLL1	-7612.0
LRR1	-7643.0
ALG13	-7645.0
APOL1	-7657.0
DYNC1H1	-7685.0
HARS2	-7708.0
GALNT9	-7716.0
RPS18	-7744.0
USP44	-7754.0
NUP133	-7762.0
SPTBN1	-7764.0
HSPG2	-7779.0
EXOC2	-7780.0
GNG2	-7795.0
UCHL5	-7861.0
GALNT8	-7869.0
SATB1	-7905.0
COG2	-7917.0
USP16	-7920.0
RPS29	-7940.0
ST8SIA1	-7949.0
INO80E	-7964.0
SENP1	-7970.0
PIGG	-8008.0
SBSPON	-8022.0
UBE2G2	-8035.0
EIF3B	-8059.0
ALG10	-8061.0
KLK1	-8081.0
RPL35	-8092.0
PHC3	-8152.0
AXIN2	-8154.0
RPL13A	-8212.0
EIF2B3	-8218.0
ALG10B	-8242.0
MCRS1	-8262.0
MRPL10	-8268.0
SKP2	-8279.0
SAE1	-8283.0
FARSB	-8294.0
POM121	-8299.0
HARS1	-8314.0
ASNS	-8316.0
ADAMTSL5	-8317.0
FBXO2	-8324.0
RECK	-8343.0
SMAD4	-8351.0
FBXW12	-8358.0
KLHL42	-8367.0
SHPRH	-8381.0
ADAMTS16	-8387.0
AAAS	-8389.0
PHC1	-8402.0
MRPS30	-8413.0
DPH6	-8472.0
NUP54	-8479.0
TNIP3	-8502.0
TTLL13P	-8507.0
MBOAT4	-8515.0
LARS2	-8516.0
MRPL50	-8537.0
MEN1	-8538.0
TOMM70	-8541.0
RPL3	-8561.0
THSD7A	-8596.0
RUVBL1	-8612.0
FKBP14	-8631.0
POMT1	-8665.0
PML	-8693.0
TRAPPC2	-8704.0
UBE2T	-8710.0
RAB38	-8714.0
INO80	-8723.0
MRPS21	-8725.0
TNKS	-8738.0
PEX12	-8753.0
COPS8	-8755.0
B4GALT6	-8785.0
PGAP1	-8788.0
ALG1	-8792.0
RPL39L	-8805.0
AARS1	-8809.0
PIGO	-8810.0
CCT2	-8825.0
KIF5C	-8865.0
FARS2	-8867.0
KIF5A	-8869.0
RPS20	-8886.0
MRPL46	-8897.0
DERL1	-8963.0
RAB2B	-8982.0
MRPS27	-9001.0
SEC11C	-9006.0
CNIH3	-9011.0
MRPL32	-9109.0
ESR1	-9122.0
PSMC4	-9127.0
TUBB4A	-9162.0
MRRF	-9198.0
PIGU	-9200.0
FBXL22	-9210.0
AGBL2	-9212.0
NARS2	-9260.0
CCNF	-9262.0
CBX5	-9272.0
WRAP53	-9335.0
CYLD	-9359.0
TATDN2	-9360.0
TRAPPC10	-9369.0
AGBL3	-9406.0
SRPRB	-9415.0
PIGH	-9444.0
NANP	-9448.0
TBCD	-9449.0
IGFBP3	-9455.0
MRPS33	-9456.0
GHRL	-9461.0
SEMA5A	-9495.0
ERN1	-9501.0
NUP43	-9517.0
NPM1	-9532.0
RPL23A	-9567.0
MRPL49	-9604.0
FBXO44	-9627.0
RGS9	-9636.0
GNPNAT1	-9662.0
DCAF5	-9664.0
ATF3	-9677.0
LMO7	-9709.0
GFPT2	-9713.0
CHD3	-9737.0
CREB3L4	-9751.0
FUT8	-9755.0
RPS27	-9756.0
ALG9	-9766.0
WFS1	-9774.0
COPS7B	-9775.0
EIF2B5	-9809.0
BMI1	-9829.0
EXOSC6	-9839.0
DDX5	-9843.0
RAB30	-9844.0
EEF2KMT	-9857.0
GALNT12	-9866.0
DCAF8	-9875.0
NR2C1	-9913.0
MRPS25	-9932.0
GNAO1	-9936.0
UHRF2	-9937.0
SPRN	-9939.0
TUBA3D	-9947.0
NOP58	-9951.0
NFYB	-9964.0
PSME1	-9991.0
IGFALS	-9994.0
DCUN1D4	-10001.0
FBXW8	-10013.0
TBCC	-10066.0
PROC	-10098.0
RAB29	-10185.0
USP37	-10210.0
PRKDC	-10219.0
B3GNT4	-10231.0
NUP155	-10233.0
HIC1	-10249.0
EXOSC9	-10250.0
CASP8AP2	-10254.0
SPON1	-10262.0
AXIN1	-10285.0
ASXL1	-10309.0
PSME2	-10336.0
SMURF2	-10340.0
MAT2B	-10365.0
GSPT2	-10403.0
NUP107	-10421.0
PTCD3	-10452.0
LMCD1	-10468.0
MRPL39	-10483.0
SIN3A	-10493.0
NUP160	-10557.0
SARS2	-10572.0
DAXX	-10575.0
AMDHD2	-10584.0
POFUT2	-10597.0
FBXO32	-10607.0
NUP35	-10611.0
STAMBPL1	-10617.0
NR3C2	-10625.0
LMAN1	-10630.0
EXOSC7	-10631.0
MRPS18B	-10642.0
HERC2	-10658.0
KLHL25	-10671.0
MUC12	-10704.0
NUP210	-10726.0
MRPL9	-10743.0
DNAJC24	-10746.0
B4GALT3	-10759.0
MPI	-10760.0
OTUD3	-10763.0
HLTF	-10765.0
RCN1	-10766.0
L3MBTL2	-10770.0
KAT2A	-10771.0
DPH7	-10779.0
FBXO21	-10790.0
SEC61A2	-10798.0
ERO1B	-10822.0
GZMH	-10827.0
ADAMTS4	-10829.0
MRPL17	-10860.0
COPZ2	-10863.0
TP53	-10893.0
UBE2Z	-10912.0
TRAPPC6A	-10917.0
HSPA8	-10922.0
NAE1	-10931.0
RAB33A	-10940.0
TNFAIP3	-10950.0
MRPS6	-10988.0
TP53BP1	-10992.0
GCNT4	-10997.0
DPH2	-11005.0
STX17	-11006.0
LYPD2	-11013.0
ADAMTS10	-11036.0
OTUD7A	-11041.0
EXOSC2	-11072.0
RIPK1	-11074.0
MRPS9	-11102.0
BIRC3	-11125.0
EXTL2	-11129.0
EIF4A2	-11157.0
RNF144A	-11164.0
ARSK	-11166.0
NSMCE4A	-11187.0
ACTR5	-11217.0
FN3KRP	-11220.0
CCT6B	-11278.0
EIF2AK3	-11279.0
ZNF131	-11283.0
UBE2L6	-11293.0
USP24	-11306.0
DCAF4	-11310.0
N6AMT1	-11314.0
NUP205	-11321.0
PSMB9	-11324.0
CUL1	-11330.0
IFIH1	-11332.0
DPH1	-11342.0
DCAF17	-11365.0
USP42	-11367.0
TSPYL2	-11374.0
RAB40B	-11375.0
NUP88	-11397.0
H2AW	-11403.0
KLHL22	-11407.0
SPTAN1	-11426.0
ADAMTS1	-11438.0
MARS2	-11449.0
XPC	-11450.0
EXOSC8	-11456.0
KLHL20	-11483.0
USP20	-11488.0
ST8SIA6	-11516.0
RAB39B	-11529.0
DDB2	-11530.0
SFTPD	-11535.0
KCTD7	-11546.0
UBE2Q2	-11554.0
WDR48	-11565.0
ST3GAL5	-11568.0
NUP93	-11620.0
NUP188	-11624.0
KLHL3	-11635.0
TARS2	-11669.0
CCNE1	-11707.0
PIGL	-11711.0
DCAF16	-11717.0
RANGAP1	-11722.0
PIGW	-11723.0
EIF5A2	-11741.0
SMAD3	-11745.0
TRAF2	-11746.0
NSMCE3	-11748.0
NOP56	-11750.0
ABCA3	-11756.0
FBXW4	-11757.0
B3GLCT	-11758.0
PARP1	-11764.0
VAMP2	-11779.0
RAB37	-11793.0
AARS2	-11821.0
CHST10	-11841.0
FBXO4	-11843.0
EID3	-11870.0
SMAD7	-11872.0
ADRB2	-11892.0
IARS1	-11897.0
RAD18	-11916.0
GATA6	-11928.0
POMGNT1	-11937.0
DDX58	-11950.0
FBXO31	-11953.0
ASB2	-11978.0
RORA	-11979.0
NUB1	-11986.0
RPA1	-12004.0
SUMF2	-12038.0
WRN	-12047.0
ST6GAL1	-12052.0
MDC1	-12059.0
EARS2	-12069.0
ST6GALNAC6	-12085.0
GNGT2	-12086.0
OTUD7B	-12095.0
COG1	-12125.0
XPNPEP2	-12151.0
RBBP7	-12155.0
UAP1	-12166.0
NDC1	-12173.0
GATA3	-12191.0
USP18	-12214.0
DNMT1	-12257.0
C3	-12262.0
NOD1	-12263.0
LY6E	-12264.0
SPON2	-12276.0
PRSS23	-12288.0
B3GNT7	-12298.0
USP28	-12317.0
USP11	-12333.0
CCL2	-12341.0

---

Post-translational protein modification

Post-translational protein modification

	842
set	Post-translational protein modification
setSize	1193
pANOVA	6.81e-19
s.dist	0.152
p.adjustANOVA	7.16e-17

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ADAMTS2	9525
FAM20A	9524
PPARG	9522
CTSA	9514
VCAN	9505
NPL	9498
ASGR2	9487
F5	9485
BST1	9480
SOCS3	9476
RAB32	9463
RAB13	9440
FAM20C	9421
FBXO9	9416
FBXL5	9410
LAMC1	9387
CKAP4	9370
RHOT1	9367
RAB31	9356
APLP2	9347

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ADAMTS2	9525
FAM20A	9524
PPARG	9522
CTSA	9514
VCAN	9505
NPL	9498
ASGR2	9487
F5	9485
BST1	9480
SOCS3	9476
RAB32	9463
RAB13	9440
FAM20C	9421
FBXO9	9416
FBXL5	9410
LAMC1	9387
CKAP4	9370
RHOT1	9367
RAB31	9356
APLP2	9347
SNX3	9326
QSOX1	9298
FSTL3	9290
H2BC21	9283
TPST1	9251
ASGR1	9212
PCSK9	9208
RAB3D	9207
UIMC1	9202
MITF	9193
ARF4	9191
UBE2D1	9187
APP	9177
KLHL2	9174
SERPINA1	9168
DCTN2	9157
SPTB	9154
VNN2	9153
CD55	9145
KDELR1	9142
ST6GALNAC3	9134
VNN1	9092
FURIN	9075
ARF1	9064
RAB1A	9052
H2BC12	9051
PHC2	9043
LGALS1	9032
NEU1	9029
ACTB	9011
SUMF1	8991
CTSZ	8975
HDAC4	8960
ALPL	8947
B3GNT8	8945
PNPLA2	8939
RAB10	8926
NLRP3	8901
OS9	8898
TGFA	8889
RAD23B	8886
NUCB1	8883
GALNT14	8844
GALNT2	8843
CMAS	8839
B4GALT5	8830
NSF	8829
NUP58	8820
ADAM10	8791
ADAMTS3	8785
ANK1	8771
RAB7A	8742
GLB1	8725
TGOLN2	8714
EDEM2	8704
USP3	8699
RNF146	8696
RAB11A	8688
TIMP1	8677
MGAT4B	8675
ST3GAL2	8669
B3GNT5	8666
TUBB2A	8659
RAB5C	8655
UBE2D3	8640
FBXL19	8620
CDC34	8611
RAB2A	8604
CAPZA2	8597
FKBP8	8579
SIAH2	8578
NRN1	8565
SOCS6	8557
RNF135	8556
UBE2R2	8548
EDEM3	8538
SMAD1	8511
ARRB2	8490
PSMB7	8485
PTEN	8460
NOD2	8442
P4HB	8440
DNAJC3	8435
PLAUR	8424
RAB34	8420
RAB27A	8411
PSMD4	8402
DCTN4	8387
GCNT1	8379
TNIP1	8378
COPA	8366
RAB20	8351
MRTFA	8350
VDR	8348
DCAF6	8336
AGTPBP1	8330
RHOA	8319
RAB1B	8313
FUCA2	8304
FN1	8284
UBE2J2	8268
PSME3	8251
ST8SIA4	8236
TRIM25	8226
GALNT7	8224
RAB40C	8215
C1GALT1C1	8153
RAB6A	8148
TRIM27	8142
CAPZA1	8135
RAB3A	8133
SEC24D	8115
PSMB5	8101
ANKRD9	8085
GAS6	8063
RPN1	8024
CAPZB	8015
H2BC5	8003
NCOR2	7985
COMMD9	7967
LTBP1	7962
NANS	7957
TMED7	7950
RAB4A	7941
H2AC6	7934
JOSD2	7931
UBE2W	7929
MAN1A1	7927
NUP214	7921
RNF7	7913
H2BC11	7912
FSTL1	7908
COPB2	7902
TTLL4	7901
CALU	7894
EPAS1	7886
ARF5	7885
NUS1	7864
WSB1	7862
VDAC2	7857
PSMD6	7846
DPH3	7837
USP4	7812
TRAPPC1	7806
RAB18	7801
CNIH1	7779
UBA3	7767
PROS1	7758
MPDU1	7751
WSB2	7743
DYNC1I2	7735
ARF3	7732
KDELR2	7728
ETFB	7688
UBE2H	7663
SEC24A	7660
TOP1	7645
MBD6	7623
PSMD9	7620
ACTR10	7605
SPTA1	7595
COPG2	7594
ARSB	7572
UBE2L3	7561
H2BC18	7547
USP10	7542
YOD1	7533
ADAMTSL4	7530
HNRNPK	7522
ELOC	7519
LRRC41	7515
H2AC11	7513
COPG1	7509
FBXO7	7498
RXRA	7495
ELOB	7482
UBE2M	7477
CFP	7445
HIF1A	7436
NR1H2	7415
PSMD2	7411
FUCA1	7408
H2BC4	7389
ARSD	7365
AMFR	7363
PIAS1	7361
TADA3	7356
COMMD8	7353
UBE2F	7341
SEC23A	7335
PSMA1	7329
COPB1	7321
TUBA1A	7313
UBE2A	7309
DCTN6	7300
H2BC17	7285
RAB33B	7267
FPGT	7264
PSMD1	7241
TUBB4B	7240
SLC35A1	7225
TUBA1C	7198
MELTF	7197
PSMB3	7171
TMED9	7167
STX5	7166
TFG	7160
RPN2	7140
MAVS	7124
TRAPPC3	7114
RAB39A	7113
TAF10	7110
RAB5A	7103
MCFD2	7099
PSMA7	7096
RAB14	7095
UBA1	7089
LMAN2	7080
GALNT4	7072
IDE	7051
CPM	7044
SUMO3	7042
PIGS	7033
F8	7022
PSMC1	7021
UBE2B	7003
ACTR1A	7002
TADA2B	6952
DYNC1LI1	6941
LMAN2L	6937
DDOST	6931
RTN4RL2	6898
COPE	6896
SUMO1	6889
VCP	6886
UBE2K	6884
SEL1L	6847
CUL3	6821
PPP6C	6819
PSMB6	6813
NFKBIA	6807
RNF123	6802
SATB2	6781
WDTC1	6779
UBE2E1	6759
XRCC4	6758
ST6GALNAC2	6746
ST3GAL6	6701
FBXO11	6698
RAB5B	6690
TDG	6672
PSMF1	6659
USP22	6652
UBB	6639
PSMC6	6635
RNF40	6628
MAN2A2	6625
GORASP1	6606
PIGF	6597
COPS7A	6590
RENBP	6585
MUC1	6573
FBXW2	6560
PSMD12	6556
IGFBP7	6545
CCDC22	6533
RAB8B	6529
DCUN1D1	6523
BECN1	6516
RAD23A	6512
GALNT1	6508
RNF185	6491
NEDD8	6482
SAR1B	6479
RAB43	6433
RARA	6429
PARK7	6421
USP8	6418
FOXO4	6391
KBTBD7	6376
PREB	6368
CALR	6340
USP7	6323
COL7A1	6304
TTLL7	6266
MGAT1	6257
BRCA1	6248
RRAGA	6244
TSTA3	6241
INO80C	6240
HNRNPC	6239
PSMD11	6231
ASB7	6221
GOLGA2	6203
FBXW11	6196
RAB21	6165
STAM2	6159
USP15	6148
BRCC3	6145
COPS2	6139
EP300	6129
HDAC7	6122
ANO8	6099
HIPK2	6078
NSMCE1	6056
RAB6B	6053
TMED2	6052
RNF181	6022
ZBED1	6017
COPS3	6005
DCTN3	5994
GPAA1	5992
AREG	5977
PSMA6	5970
LAMB1	5966
PSMD7	5963
VNN3	5958
DYNLL1	5952
THBS1	5951
PSMD13	5948
CHST8	5900
DAD1	5895
PDIA6	5882
APOA2	5879
SEC22B	5873
COMMD1	5871
B3GNT2	5868
NSMCE2	5864
CD59	5859
BCL10	5849
ST3GAL4	5781
PSMD8	5757
SEC13	5748
ALG14	5746
RNF20	5727
TPST2	5725
TUBB6	5685
TAB1	5681
CETN2	5642
RAB36	5636
NTNG2	5601
ARCN1	5580
MIA2	5574
TNIP2	5552
FBXL13	5534
CANX	5528
B3GNTL1	5520
TUBA1B	5509
TMEM115	5508
COMMD5	5497
FBXL4	5496
SP3	5490
TUBB1	5488
HDAC2	5482
USP9X	5464
CBX8	5448
PIGX	5399
SDC2	5397
H2BC9	5394
IKBKG	5377
RAB24	5354
TTLL12	5353
PSMA2	5339
TRAPPC9	5333
H2BC15	5312
TFPT	5309
STAG2	5301
WAC	5267
PPP6R1	5263
TMEM132A	5245
GGCX	5237
COMMD7	5226
PRKCSH	5220
YKT6	5205
TRAPPC5	5191
PIAS4	5184
RAE1	5164
FEM1C	5160
METTL22	5157
TGFB1	5153
KLHL5	5105
UBE2C	5101
UGGT1	5082
DCTN1	5078
KDM1B	5073
KLHL21	5054
CDC73	5020
UBE2E3	5005
GCNT3	4996
SLC17A5	4989
USP12	4974
H2AC20	4972
SUMO2	4961
GMDS	4937
DCAF10	4922
UBE2G1	4921
CISH	4915
SMAD2	4905
KEAP1	4898
UGGT2	4897
ASB8	4884
FBXL20	4844
AR	4840
FBN1	4836
UBE2S	4746
DPM2	4721
IKBKE	4715
BIRC2	4692
FBXO30	4683
UBE2D2	4657
SEC16A	4619
PSMD3	4618
NRIP1	4609
PTRH2	4601
SUDS3	4526
NUP50	4521
HGS	4513
FBXL15	4499
NCOA1	4483
C4A	4466
STS	4459
UBC	4439
TPGS1	4435
FEM1B	4426
ING2	4415
RAB11B	4402
USP48	4399
KCTD6	4371
COPS5	4361
SEM1	4348
VDAC1	4347
DCUN1D3	4333
CD109	4316
SP100	4314
FCGR3B	4313
MDM2	4312
RFT1	4309
RAB19	4300
DNMT3B	4294
B4GALT1	4292
SKP1	4287
COMMD10	4274
DYNC1LI2	4273
COG7	4269
HCFC1	4254
PEX5	4225
DYNC1I1	4187
PMM1	4176
USO1	4154
TRAPPC6B	4147
NAPG	4139
PDIA3	4128
STT3A	4095
RAB9A	4088
PSMB2	4084
COPZ1	4035
SENP2	4030
FBXL8	4021
CDC20	3998
PPARGC1A	3988
RAB35	3981
SRD5A3	3971
TMEM129	3961
ADRM1	3953
RBX1	3934
RAB42	3932
TGFBR2	3914
SERPINA10	3902
GMPPA	3886
RAB8A	3880
OTOA	3867
FN3K	3813
BIRC5	3738
ZRANB1	3730
ARFGAP3	3714
VHL	3674
ALB	3668
CLSPN	3640
SEC24B	3608
PIGB	3580
MFGE8	3534
RTF1	3526
SCFD1	3525
KIN	3521
AGBL5	3518
RNF2	3513
METTL21A	3509
ARSA	3486
PAF1	3478
FBXO17	3474
UBA6	3438
PSMD5	3426
CREBBP	3423
RAB27B	3386
PSMB1	3374
KTN1	3363
FOXK2	3358
CTR9	3344
AURKA	3330
ASB13	3324
ASB1	3319
FBXL18	3309
RNF152	3269
PPP6R3	3261
TUBB3	3242
APC	3240
COMMD2	3198
SOCS5	3184
NAGK	3158
ERCC8	3154
RAB4B	3137
DDA1	3127
PEX14	3125
NUP98	3101
SENP8	3086
NUP37	3074
DDB1	3060
DERL2	3041
PIGZ	3026
MBTPS1	2966
MUL1	2961
PEX2	2946
CDC25A	2911
UBE2V2	2902
DOLPP1	2858
TOPORS	2830
CUL4B	2802
TOP2A	2778
ETFBKMT	2766
SLC35C1	2750
KBTBD6	2724
TMED3	2720
SEMA5B	2706
ALG12	2659
RNF139	2627
SAFB	2615
MAGT1	2613
USP49	2612
PSMD14	2611
PSMC2	2598
MBD5	2592
DPM3	2577
PTP4A2	2561
GCNT7	2527
CUL2	2526
PSMB4	2523
CFTR	2416
MAP3K7	2395
CSNK1D	2390
SPSB1	2374
FBXO40	2368
CTSC	2326
MLEC	2322
MYC	2304
CHM	2273
BTBD1	2263
CBX4	2222
CST3	2206
DPAGT1	2163
HSP90B1	2059
CCP110	2050
MBD1	2028
ARRB1	1998
PSMC3	1976
UCHL3	1959
LSAMP	1958
FCSK	1950
FEM1A	1947
UBE2N	1936
UBXN1	1892
ASXL2	1856
PIGN	1847
GALNT3	1805
PIGQ	1782
COPS4	1776
RAD21	1709
PRMT3	1695
CCNA2	1685
ST8SIA5	1668
ALG6	1653
COPS6	1637
MGAT2	1633
STAMBP	1611
ATXN3	1601
ASB9	1587
TGFBR1	1585
DPM1	1567
PSMD10	1559
UBXN7	1556
CDK1	1540
NEGR1	1459
NAPA	1432
THRB	1429
CCDC8	1402
OTUB1	1400
PMM2	1394
KLHL9	1353
RTN4RL1	1345
ASB3	1325
STAM	1285
SHISA5	1269
BAP1	1126
UBA52	1121
TF	1102
SEC31A	1099
NCOA2	1092
B4GALNT2	1079
RAB23	1046
RBBP5	1037
RIPK2	1025
FBXL3	1005
SYVN1	992
PIGT	952
DCUN1D5	861
USP30	856
ADAMTSL3	855
AURKB	846
CUL5	834
PPARA	813
GALNT16	790
NUP62	769
KLHL13	702
ZBTB16	689
CNIH2	654
HLA-B	649
POMT2	624
SMC1A	613
HDAC1	587
CCNA1	585
RAB44	573
PEX13	571
EIF5A	553
CAMKMT	550
YY1	537
DHPS	525
NR3C1	511
ST3GAL3	505
LAMB2	501
IL33	445
VDAC3	436
DTL	428
B4GALT4	391
VCPKMT	334
SEC16B	330
TMED10	323
DPH5	315
EEF2	306
FBXW5	265
JOSD1	227
APOE	218
GALNT15	190
USP25	173
WDR5	155
WDR61	77
PIGM	62
LEO1	39
COG4	-6
TBC1D20	-18
B3GALNT2	-28
EDEM1	-114
GOSR1	-182
TRAF6	-229
RWDD3	-238
VCPIP1	-268
COG8	-346
USP19	-456
SEC23IP	-468
TNKS2	-499
PRSS21	-577
BET1	-594
PSMA4	-616
ST6GALNAC4	-629
FBXO41	-657
OTULIN	-683
MANEA	-699
ALG5	-708
UBE2I	-764
ICMT	-786
GALNT6	-806
RANBP2	-820
USP33	-821
RAB12	-856
PSMC5	-863
BABAM1	-897
PGM3	-906
USP34	-944
OTUB2	-980
GANAB	-986
RAD52	-1021
WDR20	-1033
COMMD6	-1053
GALNT5	-1162
NFKB2	-1165
TTLL2	-1171
MDM4	-1230
ALG2	-1259
ALG3	-1263
FBXO15	-1269
FBXL12	-1321
MAN2A1	-1349
PIAS3	-1358
COMMD3	-1363
GAN	-1414
GOSR2	-1456
PIGC	-1461
BGLAP	-1473
CHML	-1515
RAB7B	-1531
ST6GAL2	-1541
CP	-1561
NR4A2	-1601
DOHH	-1655
DCAF7	-1721
RELA	-1803
PIGV	-1810
NICN1	-1831
CDCA8	-1838
POMK	-1918
SELENOS	-1930
ARFGAP1	-1942
INO80B	-1954
SMC3	-1975
ATXN7	-1983
PUM2	-2007
MAN1A2	-2055
CSF1	-2061
CALM1	-2081
MGAT4C	-2109
KDELR3	-2117
ASB14	-2170
MSLN	-2192
MUCL1	-2211
DHDDS	-2236
TRIM13	-2263
TRAPPC2L	-2299
FBXO6	-2300
TTLL3	-2342
ENAM	-2373
MGAT3	-2391
SUZ12	-2409
KAT2B	-2414
DCAF11	-2444
RABGGTA	-2462
HIF3A	-2519
SOCS2	-2538
CD52	-2561
SEC24C	-2569
HLA-A	-2573
TAF9B	-2599
RAB3B	-2698
SERPIND1	-2722
TOP2B	-2731
TOMM20	-2743
ASB6	-2763
NAPB	-2780
NFRKB	-2874
MUC6	-2977
MTA1	-3005
B3GNT9	-3033
DNMT3A	-3039
NUP85	-3049
MOGS	-3051
MGAT5	-3072
PSMB8	-3076
NEURL2	-3097
GALNT11	-3148
TPGS2	-3167
MUC4	-3191
COG5	-3259
CUL7	-3334
GALNT10	-3341
OBSL1	-3404
BARD1	-3419
ADAMTS5	-3479
ZNF350	-3507
SPTBN5	-3531
THSD4	-3560
ALG11	-3593
NR1H3	-3597
ALG8	-3635
DOLK	-3639
MARCHF6	-3678
NGLY1	-3686
FBXO22	-3709
ADAMTS17	-3827
NEU3	-3833
PROZ	-3872
USP47	-3954
RAB41	-3974
DYNLL2	-3980
B3GNT3	-4017
SPSB2	-4034
TNC	-4039
RING1	-4063
TULP4	-4065
BMP4	-4081
DCTN5	-4086
MUC16	-4104
POMGNT2	-4115
TTLL5	-4116
PCGF2	-4135
TTL	-4136
RAB22A	-4208
KBTBD8	-4224
SEC22C	-4248
SMC6	-4277
MDGA1	-4285
GBF1	-4290
C1GALT1	-4297
RNF168	-4331
ADAMTS13	-4374
NR1I2	-4435
RAB26	-4448
RPS2	-4499
GPS1	-4517
RNF103	-4536
MUC5B	-4613
CBX2	-4617
COMMD4	-4618
RCE1	-4674
BLM	-4690
ARSG	-4773
LARGE2	-4786
CUL4A	-4810
DCUN1D2	-4811
MAN1B1	-4871
ACTR8	-4894
ANK3	-4919
BTRC	-4924
SEC22A	-5052
TRIM28	-5056
FOXK1	-5059
FBXO27	-5074
EEF1A1	-5087
SPTBN2	-5129
OTUD5	-5132
PIGP	-5179
FUOM	-5190
GNE	-5192
BTBD6	-5202
INO80D	-5234
CDKN2A	-5236
RABGGTB	-5240
USP14	-5246
TTLL11	-5257
TECTA	-5268
PSMA3	-5285
ST6GALNAC1	-5314
FOLR2	-5337
GOLGB1	-5370
COG3	-5426
RAB15	-5520
ARSJ	-5542
NUP42	-5564
DCAF13	-5572
TRAF3	-5576
ASB4	-5604
B4GAT1	-5642
MGAT4A	-5680
PSMB10	-5735
ARFGAP2	-5786
COG6	-5811
SCMH1	-5839
MVD	-5850
LARGE1	-5910
INCENP	-5956
MUC20	-5962
PCNA	-5969
PIGK	-5994
SPSB3	-6020
B4GALT2	-6034
PSMA5	-6053
USP5	-6068
SEH1L	-6069
PSME4	-6087
NUDT14	-6100
CUL9	-6106
FBXL14	-6145
MIA3	-6245
ANKRD28	-6250
DDX17	-6274
KLHL11	-6286
NUP153	-6321
STAG1	-6347
LYPD5	-6380
THRA	-6387
RNF5	-6413
FBXO10	-6427
CTBP1	-6456
GFPT1	-6462
UBA2	-6489
RAB9B	-6552
CAND1	-6554
H2BU1	-6555
PEX10	-6570
FBXW7	-6600
FGF23	-6622
FBXL16	-6648
ASB16	-6665
SENP5	-6689
TRAPPC4	-6712
ADAMTS14	-6719
TRRAP	-6722
USP13	-6737
MAN1C1	-6804
ITIH2	-6820
GOLM1	-6842
RPS27A	-6938
USP21	-6972
TPR	-7028
ADAMTS6	-7055
SMC5	-7084
OGT	-7119
POM121C	-7188
PIGA	-7195
THSD1	-7288
LYPD3	-7315
GMPPB	-7332
FBXW9	-7360
DAG1	-7379
MYSM1	-7386
BET1L	-7405
ST3GAL1	-7442
ACTL6A	-7468
MXRA8	-7477
PIAS2	-7496
GPLD1	-7524
POLB	-7537
NRN1L	-7549
ENGASE	-7552
IGFBP4	-7582
PSMA8	-7606
TTLL1	-7612
LRR1	-7643
ALG13	-7645
APOL1	-7657
DYNC1H1	-7685
GALNT9	-7716
USP44	-7754
NUP133	-7762
SPTBN1	-7764
UCHL5	-7861
GALNT8	-7869
SATB1	-7905
COG2	-7917
USP16	-7920
ST8SIA1	-7949
INO80E	-7964
SENP1	-7970
PIGG	-8008
SBSPON	-8022
UBE2G2	-8035
ALG10	-8061
PHC3	-8152
AXIN2	-8154
ALG10B	-8242
MCRS1	-8262
SKP2	-8279
SAE1	-8283
POM121	-8299
ADAMTSL5	-8317
FBXO2	-8324
RECK	-8343
SMAD4	-8351
FBXW12	-8358
KLHL42	-8367
SHPRH	-8381
ADAMTS16	-8387
AAAS	-8389
PHC1	-8402
DPH6	-8472
NUP54	-8479
TNIP3	-8502
TTLL13P	-8507
MEN1	-8538
TOMM70	-8541
THSD7A	-8596
RUVBL1	-8612
POMT1	-8665
PML	-8693
TRAPPC2	-8704
UBE2T	-8710
RAB38	-8714
INO80	-8723
TNKS	-8738
PEX12	-8753
COPS8	-8755
B4GALT6	-8785
PGAP1	-8788
ALG1	-8792
PIGO	-8810
DERL1	-8963
RAB2B	-8982
CNIH3	-9011
ESR1	-9122
PSMC4	-9127
TUBB4A	-9162
PIGU	-9200
FBXL22	-9210
AGBL2	-9212
CCNF	-9262
CBX5	-9272
CYLD	-9359
TRAPPC10	-9369
AGBL3	-9406
PIGH	-9444
NANP	-9448
IGFBP3	-9455
SEMA5A	-9495
NUP43	-9517
NPM1	-9532
FBXO44	-9627
GNPNAT1	-9662
DCAF5	-9664
LMO7	-9709
GFPT2	-9713
CHD3	-9737
FUT8	-9755
ALG9	-9766
WFS1	-9774
COPS7B	-9775
BMI1	-9829
DDX5	-9843
RAB30	-9844
EEF2KMT	-9857
GALNT12	-9866
DCAF8	-9875
NR2C1	-9913
UHRF2	-9937
SPRN	-9939
TUBA3D	-9947
NOP58	-9951
PSME1	-9991
DCUN1D4	-10001
FBXW8	-10013
PROC	-10098
RAB29	-10185
USP37	-10210
PRKDC	-10219
B3GNT4	-10231
NUP155	-10233
HIC1	-10249
CASP8AP2	-10254
SPON1	-10262
AXIN1	-10285
ASXL1	-10309
PSME2	-10336
SMURF2	-10340
MAT2B	-10365
NUP107	-10421
SIN3A	-10493
NUP160	-10557
DAXX	-10575
AMDHD2	-10584
POFUT2	-10597
FBXO32	-10607
NUP35	-10611
STAMBPL1	-10617
NR3C2	-10625
LMAN1	-10630
HERC2	-10658
KLHL25	-10671
MUC12	-10704
NUP210	-10726
DNAJC24	-10746
B4GALT3	-10759
MPI	-10760
OTUD3	-10763
HLTF	-10765
RCN1	-10766
L3MBTL2	-10770
KAT2A	-10771
DPH7	-10779
FBXO21	-10790
ADAMTS4	-10829
COPZ2	-10863
TP53	-10893
UBE2Z	-10912
TRAPPC6A	-10917
HSPA8	-10922
NAE1	-10931
RAB33A	-10940
TNFAIP3	-10950
TP53BP1	-10992
GCNT4	-10997
DPH2	-11005
STX17	-11006
LYPD2	-11013
ADAMTS10	-11036
OTUD7A	-11041
RIPK1	-11074
BIRC3	-11125
RNF144A	-11164
ARSK	-11166
NSMCE4A	-11187
ACTR5	-11217
FN3KRP	-11220
ZNF131	-11283
USP24	-11306
DCAF4	-11310
NUP205	-11321
PSMB9	-11324
CUL1	-11330
IFIH1	-11332
DPH1	-11342
DCAF17	-11365
USP42	-11367
RAB40B	-11375
NUP88	-11397
H2AW	-11403
KLHL22	-11407
SPTAN1	-11426
ADAMTS1	-11438
XPC	-11450
KLHL20	-11483
USP20	-11488
ST8SIA6	-11516
RAB39B	-11529
DDB2	-11530
KCTD7	-11546
UBE2Q2	-11554
WDR48	-11565
ST3GAL5	-11568
NUP93	-11620
NUP188	-11624
KLHL3	-11635
PIGL	-11711
DCAF16	-11717
RANGAP1	-11722
PIGW	-11723
EIF5A2	-11741
SMAD3	-11745
TRAF2	-11746
NSMCE3	-11748
FBXW4	-11757
B3GLCT	-11758
PARP1	-11764
RAB37	-11793
CHST10	-11841
FBXO4	-11843
EID3	-11870
SMAD7	-11872
ADRB2	-11892
RAD18	-11916
POMGNT1	-11937
DDX58	-11950
FBXO31	-11953
ASB2	-11978
RORA	-11979
NUB1	-11986
RPA1	-12004
SUMF2	-12038
WRN	-12047
ST6GAL1	-12052
MDC1	-12059
ST6GALNAC6	-12085
OTUD7B	-12095
COG1	-12125
XPNPEP2	-12151
RBBP7	-12155
UAP1	-12166
NDC1	-12173
GATA3	-12191
USP18	-12214
DNMT1	-12257
C3	-12262
NOD1	-12263
LY6E	-12264
SPON2	-12276
PRSS23	-12288
B3GNT7	-12298
USP28	-12317
USP11	-12333

---

Response to elevated platelet cytosolic Ca2+

Response to elevated platelet cytosolic Ca2+

	1011
set	Response to elevated platelet cytosolic Ca2+
setSize	110
pANOVA	1.25e-16
s.dist	0.457
p.adjustANOVA	1.22e-14

Top enriched genes

Top 20 genes

GeneID	Gene Rank
F5	9485
CYB5R1	9460
CD36	9444
CLU	9371
APLP2	9347
QSOX1	9298
CD63	9287
ALDOA	9249
LHFPL2	9224
FERMT3	9223
APP	9177
SERPINA1	9168
ACTN1	9094
STXBP2	9035
ITGA2B	8893
F13A1	8876
HGF	8863
TOR4A	8861
VTI1B	8850
LAMP2	8786

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
F5	9485
CYB5R1	9460
CD36	9444
CLU	9371
APLP2	9347
QSOX1	9298
CD63	9287
ALDOA	9249
LHFPL2	9224
FERMT3	9223
APP	9177
SERPINA1	9168
ACTN1	9094
STXBP2	9035
ITGA2B	8893
F13A1	8876
HGF	8863
TOR4A	8861
VTI1B	8850
LAMP2	8786
SRGN	8761
TIMP1	8677
TLN1	8525
CLEC3B	8480
SELP	8457
ITGB3	8291
FN1	8284
SYTL4	8256
ANXA5	8210
CFL1	8186
EGF	8179
CAP1	8111
GAS6	8063
LY6G6F	8023
ORM1	7971
CALU	7894
PECAM1	7855
SCCPDH	7787
PROS1	7758
MMRN1	7714
SERPINE1	7483
VEGFA	7467
ABCC4	7434
STXBP3	7424
TAGLN2	7367
SPARC	7339
VCL	7328
PSAP	7145
PRKCB	7097
HSPA5	7029
F8	7022
WDR1	6976
VEGFC	6906
VWF	6641
TUBA4A	6484
GTPBP2	6331
TMSB4X	6295
PPBP	6042
THBS1	5951
CD9	5940
PF4	5707
A1BG	5559
PFN1	5459
PHACTR2	5410
PDGFA	5293
ECM1	5176
TGFB1	5153
ACTN4	5049
OLA1	4914
CD109	4316
ALB	3668
RAB27B	3386
ENDOD1	3361
TIMP3	3296
CHID1	2811
MANF	2550
PLEK	1999
CFD	1984
APOOL	1609
TTN	1195
PRKCA	1132
TF	1102
STX4	606
FLNA	483
TMX3	-775
PLG	-1977
PCYOX1L	-2009
CALM1	-2081
ORM2	-2564
MAGED2	-2687
ITIH3	-3017
SOD1	-4862
ITIH4	-6208
SERPINF2	-6574
BRPF3	-6615
PPIA	-6766
TGFB2	-7492
SELENOP	-7771
NHLRC2	-7835
TGFB3	-7891
VEGFB	-7929
TEX264	-8366
CDC37L1	-8470
PDGFB	-8577
A2M	-9870
FAM3C	-10062
HABP4	-10921
CTSW	-11117
SERPING1	-11197
LGALS3BP	-11459

---

Platelet degranulation

Platelet degranulation

	832
set	Platelet degranulation
setSize	106
pANOVA	5.81e-16
s.dist	0.455
p.adjustANOVA	5.29e-14

Top enriched genes

Top 20 genes

GeneID	Gene Rank
F5	9485
CYB5R1	9460
CD36	9444
CLU	9371
APLP2	9347
QSOX1	9298
CD63	9287
ALDOA	9249
LHFPL2	9224
FERMT3	9223
APP	9177
SERPINA1	9168
ACTN1	9094
STXBP2	9035
ITGA2B	8893
F13A1	8876
HGF	8863
TOR4A	8861
VTI1B	8850
LAMP2	8786

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
F5	9485
CYB5R1	9460
CD36	9444
CLU	9371
APLP2	9347
QSOX1	9298
CD63	9287
ALDOA	9249
LHFPL2	9224
FERMT3	9223
APP	9177
SERPINA1	9168
ACTN1	9094
STXBP2	9035
ITGA2B	8893
F13A1	8876
HGF	8863
TOR4A	8861
VTI1B	8850
LAMP2	8786
SRGN	8761
TIMP1	8677
TLN1	8525
CLEC3B	8480
SELP	8457
ITGB3	8291
FN1	8284
SYTL4	8256
ANXA5	8210
CFL1	8186
EGF	8179
CAP1	8111
GAS6	8063
LY6G6F	8023
ORM1	7971
CALU	7894
PECAM1	7855
SCCPDH	7787
PROS1	7758
MMRN1	7714
SERPINE1	7483
VEGFA	7467
ABCC4	7434
TAGLN2	7367
SPARC	7339
VCL	7328
PSAP	7145
HSPA5	7029
F8	7022
WDR1	6976
VEGFC	6906
VWF	6641
TUBA4A	6484
GTPBP2	6331
TMSB4X	6295
PPBP	6042
THBS1	5951
CD9	5940
PF4	5707
A1BG	5559
PFN1	5459
PHACTR2	5410
PDGFA	5293
ECM1	5176
TGFB1	5153
ACTN4	5049
OLA1	4914
CD109	4316
ALB	3668
RAB27B	3386
ENDOD1	3361
TIMP3	3296
CHID1	2811
MANF	2550
PLEK	1999
CFD	1984
APOOL	1609
TTN	1195
TF	1102
FLNA	483
TMX3	-775
PLG	-1977
PCYOX1L	-2009
CALM1	-2081
ORM2	-2564
MAGED2	-2687
ITIH3	-3017
SOD1	-4862
ITIH4	-6208
SERPINF2	-6574
BRPF3	-6615
PPIA	-6766
TGFB2	-7492
SELENOP	-7771
NHLRC2	-7835
TGFB3	-7891
VEGFB	-7929
TEX264	-8366
CDC37L1	-8470
PDGFB	-8577
A2M	-9870
FAM3C	-10062
HABP4	-10921
CTSW	-11117
SERPING1	-11197
LGALS3BP	-11459

---

Toll-like Receptor Cascades

Toll-like Receptor Cascades

	1247
set	Toll-like Receptor Cascades
setSize	143
pANOVA	2.29e-15
s.dist	0.384
p.adjustANOVA	1.96e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A9	9516
S100A12	9515
S100A8	9503
CD36	9444
ITGAM	9398
CTSB	9364
NKIRAS2	9353
TLR8	9343
DUSP3	9280
TLR5	9201
UBE2D1	9187
APP	9177
IRAK3	9107
MAPK14	9104
TLR2	9103
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
ITGB2	8942

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A9	9516
S100A12	9515
S100A8	9503
CD36	9444
ITGAM	9398
CTSB	9364
NKIRAS2	9353
TLR8	9343
DUSP3	9280
TLR5	9201
UBE2D1	9187
APP	9177
IRAK3	9107
MAPK14	9104
TLR2	9103
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
ITGB2	8942
TLR1	8932
MAP2K6	8887
TLR6	8840
LY96	8795
MAP2K3	8748
UBE2D3	8640
NOD2	8442
MAPKAPK3	8382
CTSS	8372
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966
CNPY3	7761
PELI3	7716
PPP2CB	7712
RPS6KA1	7695
LY86	7667
TANK	7502
MAPK1	7493
BTK	7206
DNM3	7045
TAB2	6964
MAP2K4	6866
NFKBIA	6807
PELI1	6715
BPI	6666
UBB	6639
TICAM2	6335
TICAM1	6307
NFKB1	6277
FBXW11	6196
MAP3K8	6160
IRAK1	6131
DNM2	6089
ATF1	5706
TAB1	5681
FADD	5641
TIRAP	5640
UBE2V1	5637
TNIP2	5552
FOS	5460
IKBKG	5377
PTPN11	5314
MAP3K1	5121
CTSK	5059
PLCG2	5006
ECSIT	4918
IKBKE	4715
BIRC2	4692
UBE2D2	4657
EEA1	4641
PPP2R1A	4589
UBC	4439
DUSP6	4357
MAPK10	4325
SKP1	4287
CTSL	4231
RIPK3	4217
UNC93B1	4170
MAPKAPK2	4054
SOCS1	3947
MAPK11	3826
JUN	3722
DNM1	3587
TBK1	3229
TAB3	3160
RPS6KA2	3087
RPS6KA3	2973
PPP2R5D	2421
MAP3K7	2395
ATF2	2085
HSP90B1	2059
UBE2N	1936
MAP2K7	1654
PIK3C3	1619
AGER	1294
VRK3	1281
UBA52	1121
ELK1	1040
RIPK2	1025
NKIRAS1	375
NFKBIB	-152
TRAF6	-229
PPP2R1B	-241
HMGB1	-252
MEF2C	-293
CD180	-600
TLR7	-625
NFKB2	-1165
MAPK7	-1337
CREB1	-1378
RELA	-1803
TLR10	-2961
CTSV	-3036
DUSP7	-3211
PIK3R4	-4062
RBSN	-4542
LGMN	-4644
BTRC	-4924
IKBKB	-5386
S100B	-5457
TRAF3	-5576
TLR9	-5999
DUSP4	-6287
RPS27A	-6938
MAPK9	-7068
S100A1	-8108
IRF3	-8517
IRF7	-8657
MAPK8	-9428
IRAK2	-9548
SIGIRR	-10752
RIPK1	-11074
BIRC3	-11125
CUL1	-11330
CASP8	-11336
TLR3	-11525
RPS6KA5	-11594
SARM1	-12134
PTPN4	-12220
NOD1	-12263

---

Disease

Disease

	284
set	Disease
setSize	1355
pANOVA	2.72e-15
s.dist	0.128
p.adjustANOVA	2.18e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CSF2RA	9526
ADAMTS2	9525
WASF1	9520
CTSA	9514
FZD5	9513
IDH1	9507
VCAN	9505
CYP1B1	9502
CYP19A1	9497
F12	9492
HRH2	9466
CD163	9462
TALDO1	9456
CD36	9444
PRKACA	9429
GGT1	9426
SLC1A3	9389
ADM	9378
GNS	9360
GNG10	9349

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CSF2RA	9526.0
ADAMTS2	9525.0
WASF1	9520.0
CTSA	9514.0
FZD5	9513.0
IDH1	9507.0
VCAN	9505.0
CYP1B1	9502.0
CYP19A1	9497.0
F12	9492.0
HRH2	9466.0
CD163	9462.0
TALDO1	9456.0
CD36	9444.0
PRKACA	9429.0
GGT1	9426.0
SLC1A3	9389.0
ADM	9378.0
GNS	9360.0
GNG10	9349.0
MAOA	9346.0
LMNB1	9345.0
GPR27	9340.0
OPLAH	9330.0
FCGR1A	9323.0
GRB2	9304.0
IMPDH1	9294.0
AP1S1	9286.0
H2BC21	9283.0
IFNGR1	9273.0
IL10	9272.0
CYFIP1	9265.0
PC	9263.0
ARPC1B	9259.0
TPST1	9251.0
IFNGR2	9238.0
PHF21A	9216.0
TLR5	9201.0
UBE2D1	9187.0
NCSTN	9186.0
APP	9177.0
BSG	9172.0
KREMEN1	9149.0
SLC4A1	9141.0
ST6GALNAC3	9134.0
GPR84	9133.0
GUCY2C	9122.0
MAPK14	9104.0
TLR2	9103.0
CD14	9097.0
SYK	9076.0
FURIN	9075.0
RCOR1	9073.0
HK1	9071.0
ARF1	9064.0
MAP2K1	9063.0
FKBP1A	9056.0
H2BC12	9051.0
YWHAE	9045.0
PIK3CB	9038.0
NEU1	9029.0
TLR4	9016.0
GYG1	9013.0
ACTB	9011.0
PAPSS1	9003.0
CLTC	9000.0
QKI	8996.0
CUX1	8986.0
ADCY3	8984.0
HCK	8976.0
ANAPC15	8968.0
KL	8963.0
HDAC4	8960.0
MAML3	8957.0
AGTRAP	8956.0
MAPK3	8953.0
TLR1	8932.0
ERLIN2	8928.0
MYO10	8918.0
IL1R1	8917.0
CRK	8906.0
NLRP3	8901.0
OS9	8898.0
ARPC1A	8894.0
ITGA2B	8893.0
ENO1	8890.0
TGFA	8889.0
MAP2K6	8887.0
ERLIN1	8869.0
CHMP4B	8866.0
HGF	8863.0
TBXAS1	8862.0
FCGR2A	8845.0
GALK1	8842.0
TLR6	8840.0
NUP58	8820.0
CEBPD	8816.0
GNG5	8815.0
LY96	8795.0
RAC1	8793.0
ADAM10	8791.0
ADAMTS3	8785.0
CHMP2A	8780.0
HEXB	8776.0
RBPJ	8770.0
MAP2K3	8748.0
APBB1IP	8744.0
JAG1	8743.0
RAB7A	8742.0
AP1B1	8730.0
GLB1	8725.0
TCN2	8721.0
GCKR	8713.0
RB1	8707.0
EDEM2	8704.0
UBAP1	8701.0
MARK3	8697.0
ARPC5	8686.0
FOXO3	8682.0
MGAT4B	8675.0
PGK1	8672.0
ST3GAL2	8669.0
PYCARD	8638.0
AP2M1	8627.0
CDK5	8616.0
PRKAR1A	8607.0
MEFV	8605.0
E2F2	8601.0
IRS2	8569.0
CAPN1	8563.0
ACTG1	8562.0
WAS	8560.0
TLN1	8525.0
ARRB2	8490.0
RHOG	8487.0
PSMB7	8485.0
FGR	8478.0
TFDP1	8470.0
PTEN	8460.0
ADORA2B	8437.0
DNAJC3	8435.0
IFNAR1	8413.0
PSMD4	8402.0
CLTA	8376.0
WASF2	8369.0
AP3B1	8365.0
ENTPD1	8360.0
CHMP3	8349.0
BAG4	8328.0
SAP30	8303.0
GNB1	8294.0
ITGB3	8291.0
TXN	8285.0
FN1	8284.0
ARPC3	8277.0
COMT	8273.0
PSME3	8251.0
PPP2CA	8234.0
JAK3	8219.0
TXNRD1	8192.0
PAK2	8185.0
EGF	8179.0
CAST	8164.0
C1GALT1C1	8153.0
IQGAP1	8152.0
PTPN12	8151.0
TRIM27	8142.0
GNB2	8141.0
GBE1	8137.0
MYD88	8136.0
ATG7	8134.0
IL6R	8132.0
CHSY1	8116.0
ADAM17	8110.0
PSMB5	8101.0
GAB2	8099.0
STAT3	8098.0
SLC12A6	8097.0
GNAI2	8075.0
HSPA1A	8071.0
ATP6V1H	8064.0
MAP1LC3B	8043.0
AP2S1	8026.0
RPN1	8024.0
C3AR1	8012.0
VPS37C	8010.0
H2BC5	8003.0
NCOR2	7985.0
TAF12	7977.0
GAA	7968.0
CHUK	7966.0
PSEN1	7961.0
GNAI3	7953.0
H2AC6	7934.0
NUP214	7921.0
PRKAR1B	7918.0
H2BC11	7912.0
GNAS	7909.0
NOTCH3	7899.0
VAV1	7896.0
TBL1X	7887.0
RAF1	7879.0
NEDD4L	7875.0
ACTR2	7870.0
AKT1S1	7865.0
NUS1	7864.0
PSMD6	7846.0
PSTPIP1	7841.0
FGFR1OP2	7834.0
ACTR3	7818.0
PIK3AP1	7811.0
LYN	7809.0
SLC24A4	7789.0
TSG101	7786.0
CSNK1A1	7766.0
GSK3A	7760.0
MPDU1	7751.0
DYNC1I2	7735.0
CAPNS1	7729.0
DOCK2	7725.0
GUSB	7723.0
PPP2CB	7712.0
SLC40A1	7696.0
CASP9	7685.0
NCKAP1L	7673.0
CSF2RB	7661.0
VPS25	7638.0
P2RX4	7630.0
MAP3K11	7626.0
SH3GL1	7625.0
PSMD9	7620.0
ARSB	7572.0
POLR2E	7563.0
H2BC18	7547.0
CDC42	7537.0
ADAMTSL4	7530.0
HNRNPK	7522.0
ELOC	7519.0
ARPC4	7516.0
H2AC11	7513.0
GP9	7506.0
SLC9A9	7500.0
MAPK1	7493.0
ROCK1	7489.0
CCND3	7487.0
ELOB	7482.0
CBL	7480.0
GP1BB	7470.0
VEGFA	7467.0
NCKAP1	7462.0
CFP	7445.0
PSMD2	7411.0
MVB12A	7400.0
FXYD6	7391.0
ARPC2	7390.0
H2BC4	7389.0
BCL2L11	7384.0
IL18	7381.0
ABCD1	7346.0
GNB4	7336.0
SHOC2	7333.0
ANTXR2	7331.0
PSMA1	7329.0
VCL	7328.0
DOCK1	7314.0
ELOA	7312.0
RAP1A	7305.0
H2BC17	7285.0
AP2A2	7257.0
PSMD1	7241.0
SLC35A1	7225.0
TAF13	7217.0
BTK	7206.0
RXFP2	7189.0
RPL26L1	7176.0
PSMB3	7171.0
GYS1	7157.0
RPN2	7140.0
SLC7A7	7123.0
TAF10	7110.0
RAB5A	7103.0
GALNS	7102.0
EXT1	7098.0
PSMA7	7096.0
TYK2	7087.0
ABI1	7082.0
GTF2A2	7066.0
PPP1CB	7064.0
BRK1	7032.0
PRDX1	7030.0
F8	7022.0
PSMC1	7021.0
STAT5A	6965.0
DYNC1LI1	6941.0
SPRED2	6936.0
DDOST	6931.0
SLC22A5	6929.0
STAT5B	6925.0
CYBA	6922.0
BAD	6892.0
SUMO1	6889.0
VCP	6886.0
MAP2K4	6866.0
KDM7A	6855.0
SEL1L	6847.0
SLC2A9	6834.0
AP2A1	6832.0
PSMB6	6813.0
WASF3	6808.0
NFKBIA	6807.0
MAP2K2	6794.0
PPP2R5B	6774.0
UBE2E1	6759.0
XRCC4	6758.0
ST6GALNAC2	6746.0
PRKAR2B	6741.0
AP1M1	6711.0
H3C15	6699.5
MYO5A	6693.0
MYH9	6685.0
POLR2J	6671.0
IFNAR2	6665.0
PSMF1	6659.0
E2F3	6650.0
VWF	6641.0
UBB	6639.0
SDC4	6637.0
PSMC6	6635.0
GSK3B	6634.0
INSL3	6594.0
LMBRD1	6582.0
MUC1	6573.0
PSMD12	6556.0
PDCD6IP	6528.0
BECN1	6516.0
GALNT1	6508.0
GNG11	6495.0
RNF185	6491.0
VPS37A	6467.0
AHCYL1	6456.0
MYO9B	6424.0
CTNNB1	6408.0
ABCB6	6405.0
FOXO4	6391.0
YWHAB	6385.0
ATP1B2	6378.0
E2F1	6343.0
CALR	6340.0
PPP1CC	6330.0
TICAM1	6307.0
LTF	6306.0
LRRFIP1	6302.0
MMADHC	6291.0
APH1B	6280.0
GP1BA	6279.0
NFKB1	6277.0
SLC25A6	6264.0
ELMO1	6258.0
MGAT1	6257.0
PSMD11	6231.0
GOLGA2	6203.0
AGGF1	6191.0
VTA1	6185.0
CTDP1	6180.0
SH3KBP1	6173.0
PRKAR2A	6166.0
ANAPC11	6161.0
STAM2	6159.0
ROCK2	6138.0
PDPK1	6136.0
EP300	6129.0
HDAC7	6122.0
ABCA1	6109.0
PIK3CD	6046.0
RLN3	6033.0
AREG	5977.0
SNF8	5973.0
PSMA6	5970.0
PSMD7	5963.0
DYNLL1	5952.0
THBS1	5951.0
PSMD13	5948.0
CD9	5940.0
SGSH	5912.0
PPP2R5A	5897.0
DAD1	5895.0
BRD4	5892.0
NCOR1	5887.0
ADM2	5881.0
PDGFRA	5858.0
PGM1	5843.0
ITPR2	5842.0
MSH3	5834.0
ST3GAL4	5781.0
GTF2E2	5767.0
PSMD8	5757.0
CHMP1A	5756.0
SEC13	5748.0
ALG14	5746.0
BIN2	5745.0
PSENEN	5735.0
TPST2	5725.0
CHMP2B	5714.0
WIPF2	5713.0
GAB1	5679.0
DVL3	5656.0
FADD	5641.0
TIRAP	5640.0
ABCC6	5615.0
G6PC	5568.0
CANX	5528.0
CHMP6	5499.0
HDAC2	5482.0
BRMS1	5456.0
ETV6	5443.0
GTF2F2	5434.0
RPS9	5421.0
MAML1	5404.0
SDC2	5397.0
H2BC9	5394.0
GCLM	5391.0
BRAP	5387.0
XRCC5	5384.0
IKBKG	5377.0
NRAS	5363.0
PSMA2	5339.0
LIG4	5316.0
ACACA	5315.0
PTPN11	5314.0
H2BC15	5312.0
FXR1	5308.0
POLR2L	5305.0
PDGFA	5293.0
NOTCH2	5272.0
ADCY4	5270.0
GGCX	5237.0
CALCRL	5232.0
SLC3A2	5222.0
PRKCSH	5220.0
CSK	5219.0
VPS4B	5212.0
CDK7	5211.0
SNW1	5201.0
SAP30L	5199.0
SLC29A3	5197.0
CORO1A	5178.0
MVB12B	5175.0
GRSF1	5169.0
RAE1	5164.0
RAC2	5163.0
TGFB1	5153.0
CCNE2	5143.0
CTSG	5115.0
UBE2C	5101.0
MAPKAP1	5057.0
SYT1	5056.0
GALE	5026.0
TRAK1	5022.0
HBEGF	5013.0
PIK3R2	5010.0
ELL	5009.0
PLCG2	5006.0
SAP18	5004.0
SLC17A5	4989.0
H2AC20	4972.0
CDC25C	4969.0
FAM114A2	4963.0
KPNA4	4957.0
GTF2F1	4951.0
CHMP5	4943.0
SMAD2	4905.0
VAV3	4894.0
HMG20B	4839.0
IL1B	4807.0
SLC9A6	4781.0
FDXR	4766.0
HDAC11	4756.0
CBX1	4751.0
UBE2S	4746.0
DPM2	4721.0
HDAC5	4710.0
NOTCH1	4704.0
HDAC3	4673.0
PIK3CA	4629.0
PSMD3	4618.0
POLR2F	4604.0
PPP2R1A	4589.0
TBL1XR1	4556.0
SUDS3	4526.0
NUP50	4521.0
HGS	4513.0
CDKN1A	4511.0
RPL3L	4503.0
SLC39A4	4464.0
PTK2	4462.0
SLC16A1	4455.0
UBC	4439.0
TPMT	4422.0
ELMO2	4397.0
SOD2	4390.0
PARP4	4362.0
DUSP6	4357.0
SEM1	4348.0
NMT1	4328.0
MDM2	4312.0
RFT1	4309.0
GNG8	4296.0
B4GALT1	4292.0
LRP5	4289.0
SKP1	4287.0
DYNC1LI2	4273.0
CTSL	4231.0
CASP1	4224.0
VPS28	4199.0
RHBDF2	4197.0
DYNC1I1	4187.0
UNC93B1	4170.0
KSR1	4167.0
HYAL1	4164.0
SHC1	4161.0
EPS15	4138.0
APH1A	4133.0
PTGES3	4125.0
SLC22A18	4112.0
CDC37	4096.0
STT3A	4095.0
PSMB2	4084.0
CTBP2	4080.0
PDZD3	4005.0
AP1G1	3987.0
SRD5A3	3971.0
RBX1	3934.0
FGF2	3920.0
G6PC3	3915.0
TGFBR2	3914.0
VPS37B	3908.0
LMNA	3887.0
CYP27A1	3877.0
GTF2H5	3874.0
NELFE	3860.0
SND1	3849.0
TRIM24	3806.0
MMUT	3791.0
ARID4A	3763.0
NRG1	3750.0
JUN	3722.0
KRAS	3702.0
STRN	3695.0
VHL	3674.0
KIAA1549	3618.0
AKT1	3614.0
ERCC2	3547.0
GTF2B	3515.0
POLR2G	3508.0
P2RX7	3475.0
PRDX2	3428.0
PSMD5	3426.0
CREBBP	3423.0
RLBP1	3401.0
PSMB1	3374.0
ZMYM2	3368.0
GNAI1	3329.0
MYO1C	3310.0
ADORA2A	3293.0
SLC35A2	3255.0
APC	3240.0
TBK1	3229.0
RAP1B	3206.0
MRC1	3109.0
NUP98	3101.0
AVPR1A	3091.0
RNGTT	3088.0
HDAC8	3079.0
GATAD2A	3075.0
NUP37	3074.0
ABCG8	3056.0
DERL2	3041.0
NF1	3036.0
GTF2H2	2984.0
CDC26	2923.0
CDC25A	2911.0
GNAZ	2909.0
SUPT4H1	2890.0
CCNK	2877.0
SLC12A1	2870.0
POMC	2855.0
RAMP3	2854.0
ATP1A1	2813.0
SLC35C1	2750.0
GTF2A1	2713.0
SEMA5B	2706.0
JAK2	2691.0
EPGN	2662.0
ALG12	2659.0
ARAF	2644.0
MAGT1	2613.0
PSMD14	2611.0
SDC3	2599.0
PSMC2	2598.0
DPM3	2577.0
PSMB4	2523.0
SLC27A4	2479.0
KPNB1	2430.0
PPP2R5D	2421.0
CFTR	2416.0
CHMP4A	2400.0
MYC	2304.0
GTF2E1	2287.0
HDAC10	2280.0
SFPQ	2253.0
CLCN6	2232.0
DPAGT1	2163.0
TAF7	2139.0
RPS27L	2061.0
TSHR	2051.0
ARRB1	1998.0
MTRR	1994.0
PSMC3	1976.0
CAMK2G	1921.0
EREG	1888.0
CCNC	1877.0
HGSNAT	1867.0
FDX1	1854.0
AP1M2	1832.0
GALNT3	1805.0
RCC1	1766.0
SFTPB	1754.0
IRS1	1741.0
UGT1A1	1670.0
MAP2K7	1654.0
ALG6	1653.0
MGAT2	1633.0
PIK3C3	1619.0
POLR2C	1616.0
TGFBR1	1585.0
DPM1	1567.0
PSMD10	1559.0
SUGT1	1544.0
PTGER2	1463.0
RPIA	1441.0
PMM2	1394.0
HDAC9	1359.0
HSP90AA1	1326.0
BRAF	1308.0
KPNA1	1296.0
GP5	1295.0
STAM	1285.0
HEXA	1261.0
SLC34A2	1253.0
TAF9	1250.0
NEIL3	1194.0
GCK	1193.0
CHST14	1138.0
UBA52	1121.0
CAPN2	1064.0
ELK1	1040.0
SYVN1	992.0
KPNA3	923.0
ATP1A4	922.0
GNG3	890.0
REST	865.0
ADAMTSL3	855.0
CUL5	834.0
FKBP4	832.0
SLC25A5	826.0
VPS4A	784.0
CCNH	774.0
NUP62	769.0
GSS	715.0
RPS6KB2	700.0
ERLEC1	698.0
POMT2	624.0
SLC7A9	622.0
RDH5	591.0
HDAC1	587.0
LRP6	577.0
WIPF1	569.0
GNB5	512.0
NR3C1	511.0
ST3GAL3	505.0
ZCRB1	487.0
AHCY	466.0
SYT2	461.0
AKT2	433.0
RPS4Y1	424.0
POLR2I	396.0
MLST8	376.0
NELFB	374.0
IGHV1-2	360.0
NCKIPSD	328.0
KREMEN2	316.0
EEF2	306.0
WASL	299.0
AVPR2	291.0
SLC11A2	260.0
IGHV2-5	230.0
ABL1	226.0
ADCY9	123.0
HMGA1	117.0
IGHV3-53	103.0
RPL36AL	32.0
RPLP1	19.0
DVL1	0.0
CD86	-14.0
ARID4B	-27.0
CXCR4	-45.0
FMOD	-59.0
ITGB1	-94.0
BAIAP2	-215.0
PPP2R1B	-241.0
RPS24	-263.0
DCXR	-290.0
FAU	-362.0
FMO3	-371.0
IGHV3-7	-441.0
ERBB3	-472.0
TNKS2	-499.0
PABPN1	-526.0
MBD3	-528.0
TRADD	-556.0
ERBIN	-574.0
MAML2	-582.0
PSMA4	-616.0
IGHV1-46	-618.0
TLR7	-625.0
ST6GALNAC4	-629.0
CDC27	-651.0
IGHV3-48	-668.0
PPP2R5E	-680.0
GGT5	-695.0
FAM131B	-734.0
GPR83	-743.0
UBE2I	-764.0
IGKV3-11	-781.0
TSC2	-804.0
RANBP2	-820.0
C1QBP	-822.0
PSMC5	-863.0
GPS2	-889.0
TCEA1	-943.0
RPL15	-963.0
GANAB	-986.0
IGKV1-39	-989.0
RPLP0	-1000.0
IGLV7-46	-1016.0
CDK5R1	-1089.0
NFKB2	-1165.0
IGKV1-5	-1184.0
XPO1	-1185.0
RPL8	-1187.0
ALG2	-1259.0
ALG3	-1263.0
IGLV2-8	-1294.0
IGKV5-2	-1298.0
SLC36A2	-1307.0
IGHV3-23	-1317.0
ATP1B3	-1347.0
MAN2A1	-1349.0
CREB1	-1378.0
EXT2	-1405.0
RPS26	-1430.0
IGHV3-13	-1443.0
RPL28	-1462.0
IGLV2-18	-1524.0
IGKV1-16	-1528.0
IGLV4-69	-1559.0
CP	-1561.0
IGKV1D-39	-1574.0
SLC34A1	-1602.0
ADCY6	-1608.0
RPL22L1	-1619.0
DUSP10	-1650.0
TAF4	-1698.0
PRELP	-1738.0
RPS13	-1749.0
GATAD2B	-1759.0
POLR2K	-1783.0
RELA	-1803.0
IGHV1-69	-1822.0
TAF3	-1850.0
SV2B	-1857.0
RBBP4	-1870.0
RPL9	-1872.0
NRG4	-1875.0
IGLV10-54	-1884.0
RPL7	-1955.0
CDK8	-1971.0
IGLV1-36	-2030.0
IGKV2-30	-2045.0
ABCC2	-2079.0
CALM1	-2081.0
RPS8	-2083.0
IGLV7-43	-2089.0
VPS33B	-2091.0
MGAT4C	-2109.0
IGLV3-19	-2111.0
ANAPC16	-2123.0
IGHV3-11	-2134.0
SLC33A1	-2142.0
GNG4	-2154.0
MSH6	-2180.0
MUCL1	-2211.0
FZR1	-2233.0
GTF2H3	-2235.0
DHDDS	-2236.0
AP1S2	-2261.0
IGKV3-15	-2297.0
GNB3	-2397.0
SUZ12	-2409.0
KAT2B	-2414.0
IGKV1-33	-2424.0
ALDOB	-2431.0
HTR7	-2438.0
IGHV3-30	-2484.0
POLR2B	-2523.0
IGKV4-1	-2532.0
HLA-A	-2573.0
NEURL1B	-2586.0
TAF9B	-2599.0
IDS	-2621.0
DPEP2	-2705.0
AP2B1	-2709.0
PLK2	-2748.0
PAPSS2	-2810.0
RPL27	-2855.0
IGKV1-17	-2871.0
IGLV2-23	-2878.0
IGLV6-57	-2885.0
IGHV4-59	-2892.0
SLC26A2	-2893.0
DPEP3	-2894.0
ADCY2	-2896.0
IGLV2-11	-2905.0
GTF2H1	-2913.0
GTF2H4	-2916.0
B3GAT3	-2928.0
TAF11	-2938.0
POLR2H	-2942.0
STX1B	-2952.0
TLR10	-2961.0
MUC6	-2977.0
SV2C	-2979.0
IGHV3-33	-2988.0
PHB	-2995.0
MIB1	-2998.0
MTA1	-3005.0
RPL39	-3006.0
IGHV4-34	-3016.0
NUP85	-3049.0
MOGS	-3051.0
MGAT5	-3072.0
PSMB8	-3076.0
IGKV3-20	-3085.0
POLR2A	-3092.0
IGHV2-70	-3138.0
MUC4	-3191.0
DUSP7	-3211.0
IGLV1-44	-3258.0
ADCY7	-3286.0
FGFR4	-3293.0
RPL23	-3314.0
RPL6	-3354.0
KSR2	-3361.0
HRAS	-3382.0
RPL13	-3431.0
FRS2	-3433.0
ADAMTS5	-3479.0
IGHG3	-3481.0
THSD4	-3560.0
RPL4	-3582.0
ALG11	-3593.0
RPL29	-3611.0
ALG8	-3635.0
DOLK	-3639.0
RPL7A	-3665.0
RPS15	-3673.0
CYP27B1	-3807.0
CYP24A1	-3820.0
ADAMTS17	-3827.0
CD19	-3843.0
NELFA	-3886.0
IGKV3D-20	-3894.0
CDK9	-3927.0
RPL37A	-3946.0
KANK1	-3964.0
MYO18A	-3970.0
DYNLL2	-3980.0
POLR2D	-4024.0
STX1A	-4052.0
VAV2	-4055.0
PIK3R4	-4062.0
GOLGA4	-4064.0
RPS21	-4079.0
MUC16	-4104.0
KCNJ11	-4105.0
IGLV3-1	-4159.0
FGF7	-4247.0
GPC2	-4280.0
CYP7B1	-4294.0
C1GALT1	-4297.0
CHST6	-4347.0
AMN	-4361.0
ADAMTS13	-4374.0
PARP9	-4400.0
HTR6	-4426.0
IGKC	-4428.0
XRCC6	-4471.0
B3GALT6	-4474.0
RPS2	-4499.0
TAF5	-4514.0
CHD4	-4515.0
RPL31	-4541.0
CSPG4	-4549.0
IGHV4-39	-4582.0
ACY1	-4587.0
MUC5B	-4613.0
GPC1	-4627.0
RPS16	-4669.0
RPS3A	-4694.0
RPS28	-4713.0
SLC5A2	-4725.0
RPL5	-4728.0
GPC4	-4730.0
IGLV3-21	-4735.0
RPL22	-4740.0
ABCC9	-4745.0
BANF1	-4752.0
NAGLU	-4761.0
CNKSR2	-4781.0
IGLV1-40	-4788.0
MAN1B1	-4871.0
BTRC	-4924.0
IGLV3-25	-4933.0
IGLV1-51	-4956.0
PARP6	-4959.0
RPS7	-4968.0
ANAPC10	-5000.0
CDK2	-5006.0
FDX2	-5019.0
AKAP9	-5020.0
TRIM28	-5056.0
RPL18	-5080.0
CRHR2	-5119.0
ANAPC7	-5181.0
GNE	-5192.0
GNG7	-5198.0
CCNT2	-5205.0
NOTCH4	-5229.0
CDKN2A	-5236.0
SLC6A20	-5271.0
IGLC7	-5281.0
PSMA3	-5285.0
RPL36	-5287.0
SLC5A5	-5330.0
FGFR1	-5352.0
IKBKB	-5386.0
CD4	-5406.0
IGLV8-61	-5427.0
FXYD1	-5429.0
RPL17	-5431.0
ABCB4	-5440.0
IGKV1-12	-5446.0
RPS14	-5463.0
NOXA1	-5464.0
IGLC3	-5477.0
SLC2A10	-5478.0
IGLC2	-5510.0
PMS2	-5514.0
AP1S3	-5522.0
NUP42	-5564.0
TRAF3	-5576.0
MAMLD1	-5584.0
NHLRC1	-5628.0
IGKV2D-28	-5634.0
B4GAT1	-5642.0
MGAT4A	-5680.0
RPS5	-5691.0
SOS1	-5700.0
PSMB10	-5735.0
RPS15A	-5742.0
FXYD2	-5748.0
RPS10	-5793.0
RPL24	-5799.0
IGKV2-28	-5808.0
IDUA	-5830.0
RPL38	-5840.0
NCBP1	-5853.0
IGLV5-45	-5869.0
IGLV3-27	-5874.0
LARGE1	-5910.0
RPS3	-5914.0
TAF2	-5945.0
MUC20	-5962.0
NT5E	-5964.0
RPS12	-5987.0
TLR9	-5999.0
RPL35A	-6015.0
IGLV1-47	-6018.0
DUT	-6046.0
PSMA5	-6053.0
SEH1L	-6069.0
RPL18A	-6070.0
CDC16	-6071.0
PSME4	-6087.0
CPSF6	-6137.0
VIPR1	-6156.0
IGLC1	-6157.0
RPS6	-6160.0
MRAS	-6172.0
ENTPD5	-6179.0
TCF7L2	-6185.0
CRBN	-6190.0
IGHG1	-6201.0
RPS17	-6247.0
RPL27A	-6257.0
RPL11	-6261.0
NELFCD	-6277.0
RPL19	-6281.0
RPS4X	-6285.0
RPS23	-6292.0
NUP153	-6321.0
RPSA	-6323.0
SLC37A4	-6333.0
RPS25	-6365.0
FOXO6	-6367.0
RPL37	-6375.0
RNF5	-6413.0
TAF15	-6454.0
CTBP1	-6456.0
RPL21	-6458.0
GFPT1	-6462.0
CDK6	-6465.0
FZD7	-6508.0
FZD6	-6525.0
RPL10	-6534.0
H2BU1	-6555.0
FBXW7	-6600.0
RPL26	-6612.0
FGF23	-6622.0
GPR15	-6636.0
CNTRL	-6639.0
ANAPC4	-6644.0
DUSP16	-6655.0
RPL10A	-6686.0
RPL32	-6709.0
RPL14	-6710.0
SUPT5H	-6716.0
ADAMTS14	-6719.0
NR4A1	-6756.0
PPIA	-6766.0
RAN	-6791.0
PDCD1	-6792.0
RPL34	-6802.0
SPRED3	-6835.0
CD80	-6841.0
VPS36	-6848.0
HSP90AB1	-6863.0
RPL41	-6866.0
MLH1	-6872.0
MMACHC	-6876.0
SLC35D1	-6904.0
KPNA2	-6910.0
IGHG4	-6911.0
B2M	-6920.0
RPS27A	-6938.0
TUBB	-6956.0
RPS19	-6965.0
CCND1	-6970.0
RPL30	-7020.0
TPR	-7028.0
RPL12	-7053.0
ADAMTS6	-7055.0
BCR	-7071.0
RPLP2	-7087.0
CNKSR1	-7089.0
GPBAR1	-7132.0
FZD8	-7138.0
NAPEPLD	-7168.0
POM121C	-7188.0
KHK	-7193.0
FXYD7	-7230.0
RPS11	-7243.0
IGHG2	-7250.0
THSD1	-7288.0
MTA2	-7317.0
SLC34A3	-7335.0
TAF6	-7352.0
IGLV3-12	-7358.0
B4GALT7	-7367.0
RPL36A	-7376.0
DAG1	-7379.0
ANAPC2	-7407.0
ST3GAL1	-7442.0
DERL3	-7467.0
CUBN	-7513.0
TRAT1	-7535.0
PSMA8	-7606.0
ITPR1	-7629.0
ALG13	-7645.0
ADRB1	-7674.0
CYSLTR1	-7675.0
DYNC1H1	-7685.0
PSEN2	-7718.0
SIGMAR1	-7732.0
RPS18	-7744.0
NUP133	-7762.0
HSPG2	-7779.0
ERCC3	-7783.0
GNG2	-7795.0
ZFYVE9	-7848.0
OGG1	-7915.0
FIP1L1	-7928.0
RPS29	-7940.0
PCCB	-7976.0
SBSPON	-8022.0
RAMP1	-8039.0
TAF4B	-8069.0
RPL35	-8092.0
NTHL1	-8134.0
NEIL1	-8179.0
CD8B	-8188.0
CDKN1B	-8207.0
RPL13A	-8212.0
ADCY5	-8235.0
HES1	-8266.0
SKP2	-8279.0
POM121	-8299.0
SLC3A1	-8302.0
ADAMTSL5	-8317.0
HDAC6	-8337.0
IGLV2-14	-8345.0
SMAD4	-8351.0
LFNG	-8372.0
ADAMTS16	-8387.0
AAAS	-8389.0
PARP10	-8400.0
CTNND1	-8403.0
PARP8	-8409.0
ABCD4	-8420.0
TAF1	-8476.0
NUP54	-8479.0
PACS1	-8486.0
RPL3	-8561.0
PDGFB	-8577.0
THSD7A	-8596.0
FGF22	-8607.0
CBLL1	-8620.0
VAMP1	-8625.0
RLN2	-8636.0
SPRED1	-8639.0
PCCA	-8664.0
POMT1	-8665.0
MNAT1	-8687.0
PML	-8693.0
TNKS	-8738.0
FGF9	-8761.0
ALG1	-8792.0
CHMP7	-8802.0
RPL39L	-8805.0
SRC	-8820.0
CCR5	-8861.0
RPS20	-8886.0
DERL1	-8963.0
CYSLTR2	-8970.0
MCCC1	-8976.0
FXYD3	-8981.0
KLKB1	-9019.0
UVRAG	-9024.0
MMAB	-9046.0
EIF2AK2	-9116.0
ATP1B1	-9118.0
ESR1	-9122.0
PTGIR	-9126.0
PSMC4	-9127.0
TBP	-9167.0
GALT	-9201.0
S1PR1	-9211.0
ESR2	-9250.0
HHAT	-9301.0
SLC35A3	-9305.0
EED	-9348.0
CPSF4	-9416.0
MAPK8	-9428.0
KDM1A	-9430.0
MTA3	-9433.0
ICOS	-9434.0
FOXO1	-9465.0
CCNT1	-9469.0
SEMA5A	-9495.0
PIK3R1	-9505.0
NUP43	-9517.0
NPM1	-9532.0
NCBP2	-9558.0
RPL23A	-9567.0
TXNIP	-9600.0
RANBP1	-9657.0
RICTOR	-9670.0
CD320	-9704.0
CHD3	-9737.0
EZH2	-9741.0
PSIP1	-9743.0
HEY2	-9752.0
FUT8	-9755.0
RPS27	-9756.0
ALG9	-9766.0
MTOR	-9767.0
DDX5	-9843.0
GALNT12	-9866.0
IMPDH2	-9916.0
CYP2R1	-9918.0
GPR150	-9942.0
CAMK4	-9956.0
PSME1	-9991.0
ZC3HAV1	-10064.0
PORCN	-10074.0
CD28	-10202.0
NUP155	-10233.0
SPON1	-10262.0
AXIN1	-10285.0
ITPR3	-10308.0
PSME2	-10336.0
CYFIP2	-10367.0
NUP107	-10421.0
PRKX	-10428.0
SIN3A	-10493.0
NUP160	-10557.0
DAXX	-10575.0
IPO5	-10591.0
FEN1	-10593.0
NUP35	-10611.0
STAT2	-10637.0
GPR25	-10677.0
MUC12	-10704.0
NUP210	-10726.0
EPM2A	-10751.0
MPI	-10760.0
KAT2A	-10771.0
ADAMTS4	-10829.0
MECP2	-10855.0
SV2A	-10890.0
P2RY11	-10907.0
ABI2	-10915.0
JAK1	-10955.0
MPRIP	-10959.0
ANAPC5	-10967.0
KIT	-11004.0
MUTYH	-11016.0
ADAMTS10	-11036.0
ITGA4	-11043.0
JAG2	-11044.0
LIG1	-11053.0
SLC24A1	-11057.0
MIB2	-11073.0
RIPK1	-11074.0
RNMT	-11086.0
PLCG1	-11120.0
DVL2	-11152.0
SSRP1	-11162.0
TENT4A	-11168.0
MC1R	-11184.0
SERPING1	-11197.0
SLC2A1	-11236.0
CDK4	-11256.0
PPP2R5C	-11265.0
PEBP1	-11270.0
AMER1	-11301.0
CDC23	-11304.0
NUP205	-11321.0
PSMB9	-11324.0
CUL1	-11330.0
CASP8	-11336.0
SLC12A3	-11355.0
SUPT16H	-11359.0
NUP88	-11397.0
H2AW	-11403.0
ADAMTS1	-11438.0
DBP	-11441.0
NCK1	-11454.0
MMAA	-11476.0
MSH2	-11484.0
CDH1	-11500.0
TLR3	-11525.0
CD3G	-11526.0
SFTPD	-11535.0
ATP1A3	-11543.0
PDGFRB	-11545.0
WDR48	-11565.0
NUP93	-11620.0
NUP188	-11624.0
NEURL1	-11633.0
DUSP8	-11639.0
FZD4	-11650.0
FYN	-11675.0
GCLC	-11691.0
GPR20	-11696.0
PTGER4	-11697.0
CCNE1	-11707.0
HLCS	-11710.0
RANGAP1	-11722.0
STAT1	-11727.0
CCND2	-11734.0
SLC4A4	-11735.0
SMAD3	-11745.0
TRAF2	-11746.0
ABCA3	-11756.0
B3GLCT	-11758.0
PARP1	-11764.0
AGRN	-11770.0
VAMP2	-11779.0
FGFR2	-11785.0
CAMK2D	-11816.0
SLC20A2	-11823.0
PARP16	-11830.0
LCK	-11838.0
AKT3	-11849.0
MCCC2	-11857.0
SLC25A4	-11858.0
PARP14	-11869.0
DLL1	-11885.0
SCT	-11886.0
ADRB2	-11892.0
KPNA5	-11893.0
RNF213	-11905.0
CDKN1C	-11931.0
POMGNT1	-11937.0
PRKACB	-11959.0
ANAPC1	-11962.0
APOBEC3G	-11967.0
PRR5	-11985.0
MTR	-11996.0
CYP2U1	-12000.0
FCGR3A	-12005.0
PIK3R3	-12015.0
CDC25B	-12017.0
PTGDR	-12021.0
ISG15	-12032.0
NMT2	-12035.0
ST6GAL1	-12052.0
GNGT2	-12086.0
GIPR	-12100.0
AGK	-12120.0
RNF43	-12121.0
YES1	-12142.0
VIPR2	-12153.0
RBBP7	-12155.0
BTD	-12170.0
NDC1	-12173.0
C3	-12262.0
CYP4F22	-12271.0
SPON2	-12276.0
ERBB2	-12320.0
ZBP1	-12325.0
CD247	-12345.0
TFDP2	-12364.0
FASLG	-12371.0

---

Asparagine N-linked glycosylation

Asparagine N-linked glycosylation

	86
set	Asparagine N-linked glycosylation
setSize	269
pANOVA	5.32e-15
s.dist	0.277
p.adjustANOVA	4.03e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CTSA	9514
NPL	9498
ASGR2	9487
F5	9485
ASGR1	9212
ARF4	9191
SERPINA1	9168
DCTN2	9157
SPTB	9154
CD55	9145
KDELR1	9142
ST6GALNAC3	9134
ARF1	9064
RAB1A	9052
NEU1	9029
CTSZ	8975
OS9	8898
TGFA	8889
RAD23B	8886
CMAS	8839

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CTSA	9514
NPL	9498
ASGR2	9487
F5	9485
ASGR1	9212
ARF4	9191
SERPINA1	9168
DCTN2	9157
SPTB	9154
CD55	9145
KDELR1	9142
ST6GALNAC3	9134
ARF1	9064
RAB1A	9052
NEU1	9029
CTSZ	8975
OS9	8898
TGFA	8889
RAD23B	8886
CMAS	8839
B4GALT5	8830
NSF	8829
ANK1	8771
GLB1	8725
EDEM2	8704
MGAT4B	8675
ST3GAL2	8669
CAPZA2	8597
EDEM3	8538
DCTN4	8387
COPA	8366
RAB1B	8313
ST8SIA4	8236
CAPZA1	8135
SEC24D	8115
RPN1	8024
CAPZB	8015
NANS	7957
TMED7	7950
MAN1A1	7927
COPB2	7902
ARF5	7885
NUS1	7864
TRAPPC1	7806
CNIH1	7779
MPDU1	7751
DYNC1I2	7735
ARF3	7732
KDELR2	7728
SEC24A	7660
ACTR10	7605
SPTA1	7595
COPG2	7594
COPG1	7509
FUCA1	7408
AMFR	7363
SEC23A	7335
COPB1	7321
DCTN6	7300
FPGT	7264
SLC35A1	7225
TMED9	7167
STX5	7166
TFG	7160
RPN2	7140
TRAPPC3	7114
MCFD2	7099
LMAN2	7080
F8	7022
PSMC1	7021
ACTR1A	7002
DYNC1LI1	6941
LMAN2L	6937
DDOST	6931
COPE	6896
VCP	6886
SEL1L	6847
PPP6C	6819
ST6GALNAC2	6746
ST3GAL6	6701
UBB	6639
MAN2A2	6625
GORASP1	6606
RENBP	6585
RNF185	6491
SAR1B	6479
PREB	6368
CALR	6340
COL7A1	6304
MGAT1	6257
TSTA3	6241
GOLGA2	6203
TMED2	6052
DCTN3	5994
AREG	5977
DYNLL1	5952
CHST8	5900
DAD1	5895
SEC22B	5873
CD59	5859
ST3GAL4	5781
SEC13	5748
ALG14	5746
ARCN1	5580
MIA2	5574
CANX	5528
TMEM115	5508
TRAPPC9	5333
PPP6R1	5263
PRKCSH	5220
YKT6	5205
TRAPPC5	5191
UGGT1	5082
DCTN1	5078
SLC17A5	4989
GMDS	4937
UGGT2	4897
DPM2	4721
SEC16A	4619
UBC	4439
RFT1	4309
B4GALT1	4292
DYNC1LI2	4273
COG7	4269
DYNC1I1	4187
PMM1	4176
USO1	4154
TRAPPC6B	4147
NAPG	4139
PDIA3	4128
STT3A	4095
COPZ1	4035
SRD5A3	3971
GMPPA	3886
ARFGAP3	3714
SEC24B	3608
SCFD1	3525
PPP6R3	3261
NAGK	3158
DERL2	3041
DOLPP1	2858
SLC35C1	2750
TMED3	2720
ALG12	2659
RNF139	2627
MAGT1	2613
DPM3	2577
CSNK1D	2390
CTSC	2326
MLEC	2322
DPAGT1	2163
FCSK	1950
UBXN1	1892
ST8SIA5	1668
ALG6	1653
MGAT2	1633
DPM1	1567
NAPA	1432
PMM2	1394
UBA52	1121
SEC31A	1099
B4GALNT2	1079
SYVN1	992
CNIH2	654
ST3GAL3	505
B4GALT4	391
SEC16B	330
TMED10	323
COG4	-6
TBC1D20	-18
EDEM1	-114
GOSR1	-182
COG8	-346
SEC23IP	-468
BET1	-594
ST6GALNAC4	-629
MANEA	-699
ALG5	-708
PGM3	-906
GANAB	-986
ALG2	-1259
ALG3	-1263
MAN2A1	-1349
GOSR2	-1456
ST6GAL2	-1541
ARFGAP1	-1942
MAN1A2	-2055
MGAT4C	-2109
KDELR3	-2117
DHDDS	-2236
TRIM13	-2263
TRAPPC2L	-2299
MGAT3	-2391
SEC24C	-2569
NAPB	-2780
MOGS	-3051
MGAT5	-3072
COG5	-3259
SPTBN5	-3531
ALG11	-3593
ALG8	-3635
DOLK	-3639
MARCHF6	-3678
NGLY1	-3686
NEU3	-3833
DYNLL2	-3980
DCTN5	-4086
SEC22C	-4248
GBF1	-4290
RNF103	-4536
MAN1B1	-4871
ANK3	-4919
SEC22A	-5052
SPTBN2	-5129
FUOM	-5190
GNE	-5192
ST6GALNAC1	-5314
GOLGB1	-5370
COG3	-5426
MGAT4A	-5680
ARFGAP2	-5786
COG6	-5811
MVD	-5850
B4GALT2	-6034
NUDT14	-6100
MIA3	-6245
ANKRD28	-6250
RNF5	-6413
GFPT1	-6462
TRAPPC4	-6712
MAN1C1	-6804
RPS27A	-6938
GMPPB	-7332
BET1L	-7405
ST3GAL1	-7442
ENGASE	-7552
ALG13	-7645
DYNC1H1	-7685
SPTBN1	-7764
COG2	-7917
ST8SIA1	-7949
ALG10	-8061
ALG10B	-8242
TRAPPC2	-8704
B4GALT6	-8785
ALG1	-8792
DERL1	-8963
CNIH3	-9011
TRAPPC10	-9369
NANP	-9448
GNPNAT1	-9662
GFPT2	-9713
FUT8	-9755
ALG9	-9766
AMDHD2	-10584
LMAN1	-10630
B4GALT3	-10759
MPI	-10760
COPZ2	-10863
TRAPPC6A	-10917
STX17	-11006
SPTAN1	-11426
ST8SIA6	-11516
ST3GAL5	-11568
CHST10	-11841
ST6GAL1	-12052
ST6GALNAC6	-12085
COG1	-12125
UAP1	-12166

---

Metabolism of lipids

Metabolism of lipids

	644
set	Metabolism of lipids
setSize	626
pANOVA	6.7e-15
s.dist	0.182
p.adjustANOVA	4.81e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PPARG	9522
PLBD1	9521
CTSA	9514
CYP1B1	9502
CYP19A1	9497
PLB1	9490
HADHB	9450
CD36	9444
HSD3B7	9441
PLIN3	9437
PRKACA	9429
GGT1	9426
PCTP	9376
ACOX2	9373
TSPO	9351
TNFAIP8L3	9316
GPX1	9314
PLD1	9306
LTA4H	9261
AGPAT2	9256

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PPARG	9522
PLBD1	9521
CTSA	9514
CYP1B1	9502
CYP19A1	9497
PLB1	9490
HADHB	9450
CD36	9444
HSD3B7	9441
PLIN3	9437
PRKACA	9429
GGT1	9426
PCTP	9376
ACOX2	9373
TSPO	9351
TNFAIP8L3	9316
GPX1	9314
PLD1	9306
LTA4H	9261
AGPAT2	9256
ACSL1	9217
SGMS2	9213
OLAH	9184
PLA2G4A	9180
ACER3	9165
DGAT2	9158
PTGR1	9126
CRLS1	9116
FIG4	9115
CERS2	9108
SBF2	9078
MTMR3	9069
ARF1	9064
GM2A	9059
PIK3CB	9038
VAPA	9033
NEU1	9029
INPPL1	9028
CARM1	9020
ALOX5	9001
SUMF1	8991
GK	8973
GBA	8969
PPT1	8950
PNPLA2	8939
MTF1	8925
CRAT	8920
PISD	8908
ME1	8892
TBXAS1	8862
ACOX1	8859
HSD17B4	8858
CHPT1	8846
FAR2	8808
ACSL4	8802
SGMS1	8782
HEXB	8776
FAR1	8754
PLA2G15	8747
PECR	8739
GLB1	8725
ELOVL3	8710
HADHA	8694
SMARCD3	8668
BMX	8664
ALDH3B1	8663
PGS1	8654
GDE1	8642
LPCAT3	8609
LPCAT2	8606
SPTLC1	8588
LPGAT1	8574
GLA	8570
SPTLC2	8547
ACSS3	8546
MBOAT7	8536
ASAH1	8529
GPCPD1	8527
SLC44A1	8526
GLTP	8477
PTGS1	8467
PTEN	8460
GALC	8443
ALOX15B	8427
MBOAT2	8362
VDR	8348
SLC27A1	8305
ACAA1	8292
ACADVL	8290
PLIN2	8261
SP1	8193
TXNRD1	8192
GPAT3	8177
AGPAT1	8158
SEC24D	8115
LBR	8102
HMGCR	8094
ARNT	8047
MTMR14	8032
ACOT8	8018
HSD17B11	8008
NCOR2	7985
MTMR10	7964
PLPP3	7955
SRD5A1	7951
RAB4A	7941
ABHD5	7915
CERT1	7889
TBL1X	7887
ALOX5AP	7881
MTMR6	7878
PCYT1B	7858
ACSL3	7840
ALAS1	7804
GLIPR1	7739
ARF3	7732
PNPLA8	7709
ELOVL7	7706
FADS1	7699
MGLL	7694
SEC24A	7660
SPHK1	7657
NFYC	7653
RGL1	7647
DHRS7B	7629
CDK19	7618
SAMD8	7614
ARSB	7572
ALOX12	7559
GPD2	7555
MED8	7535
RXRA	7495
AHR	7479
HPGD	7416
NR1H2	7415
STARD3NL	7374
FDFT1	7372
ARSD	7365
PLD3	7364
ABCD1	7346
SEC23A	7335
G0S2	7272
PIK3R6	7270
IDI1	7247
HSD17B12	7181
PLD2	7180
PSAP	7145
RAB5A	7103
RAB14	7095
ELOVL1	7088
PPP1CB	7064
OSBPL8	6960
ABHD3	6943
SLC22A5	6929
HACD4	6870
PNPLA6	6863
CYP51A1	6844
PCYT1A	6816
PTDSS1	6778
GNPAT	6753
MED20	6743
SREBF2	6695
DHCR7	6676
CDS2	6557
SREBF1	6539
CPT2	6538
NUDT19	6494
SAR1B	6479
PIP5K1B	6450
OCRL	6442
INSIG2	6430
ABHD4	6425
OSBPL9	6404
RUFY1	6399
CSNK2A2	6388
PPP1CC	6330
SYNJ1	6296
CYP4F3	6259
UGCG	6247
DBI	6227
CDIPT	6222
MED25	6209
CSNK2A1	6199
MTM1	6198
DEGS1	6169
EHHADH	6140
EP300	6129
PIP5K1A	6110
ABCA1	6109
MED13L	6077
CHKA	6073
PIK3CD	6046
GDPD3	6027
FABP5	6021
ELOVL5	6011
ACOX3	5995
ORMDL2	5967
ESRRA	5943
NCOR1	5887
APOA2	5879
CPNE3	5872
PTDSS2	5867
CERS6	5795
PITPNM1	5791
NCOA6	5773
NDUFAB1	5759
ABCC3	5717
SPNS2	5710
PLA2G12A	5705
PLAAT1	5692
TNFAIP8L2	5671
B3GALNT1	5619
ACAT1	5542
MBOAT1	5500
AGPS	5495
MCAT	5450
ACOT9	5446
ACOT13	5423
HMGCL	5349
FDPS	5335
ACACA	5315
DECR1	5313
DGAT1	5306
MED16	5278
PIAS4	5184
ACLY	5159
GPX4	5150
OSBPL2	5117
PTGES	5102
CPT1A	5077
CYP2C9	5042
PIK3R2	5010
SUMO2	4961
SLC25A1	4955
ACAD10	4823
AGPAT3	4809
STARD10	4808
FDXR	4766
PTGS2	4753
ACOXL	4749
HSD17B13	4718
HDAC3	4673
SPTSSA	4652
PIK3CA	4629
NSDHL	4594
TBL1XR1	4556
HACD1	4548
FHL2	4524
NCOA1	4483
STS	4459
SCP2	4454
OSBPL6	4419
MED18	4396
MED26	4395
ACADS	4297
SQLE	4211
GPAT4	4177
PTGES3	4125
HSD17B2	4085
PPP1CA	4069
MAPKAPK2	4054
SCD	4026
PPARGC1A	3988
SRD5A3	3971
CSNK2B	3969
SLC25A20	3958
CYP27A1	3877
HSD11B2	3838
ACSM6	3832
PLA2R1	3812
FABP2	3805
MED22	3802
MMUT	3791
MID1IP1	3706
ALB	3668
HSD17B1	3654
CPTP	3651
SEC24B	3608
LIPH	3546
AKR1B15	3541
NCOA3	3522
NFYA	3506
ARSA	3486
CREBBP	3423
ACAA2	3421
PIP5K1C	3419
STARD7	3407
STARD3	3342
SGPL1	3332
PMVK	3317
ACBD7	3315
MED19	3243
MED4	3215
PIKFYVE	3187
TMEM86B	3138
PEMT	3103
MED17	3084
GLB1L	2992
GBA2	2974
MBTPS1	2966
MTMR4	2951
PHOSPHO1	2944
POMC	2855
SPHK2	2827
TAZ	2754
SLC44A2	2700
DHCR24	2694
MSMO1	2557
MED13	2533
SMPD2	2476
KPNB1	2430
PTPMT1	2213
VAPB	2194
PLPP2	2186
ACER2	2074
CBR1	2037
MED12	2034
PRKAG2	2015
CAV1	1969
CCNC	1877
SPTLC3	1857
FDX1	1854
PIK3CG	1833
PIK3C2G	1737
PIK3C3	1619
FADS2	1486
MED31	1462
MTMR9	1453
LRP2	1307
TECRL	1306
HEXA	1261
PTGR2	1238
HTD2	1183
GSTM4	1181
SMPD1	1129
CEPT1	1127
PRKD3	1104
NCOA2	1092
NUDT7	1086
PLA2G4D	1068
CSNK1G2	887
PLEKHA4	838
ALDH3A2	833
PPARA	813
DECR2	783
NPAS2	712
ABCC1	576
ECI1	486
AKR1C1	473
THRAP3	388
AACS	351
MED7	224
MBTPS2	83
CYP1A2	38
FAM120B	-8
ENPP6	-56
VAC14	-124
LCLAT1	-177
MED14	-203
ACSF3	-347
LTC4S	-353
TNFAIP8	-460
GRHL1	-492
PLAAT2	-544
MED11	-560
CYP46A1	-580
FASN	-690
GGT5	-695
ACADL	-726
UBE2I	-764
SLC27A3	-798
ACOT11	-823
MED6	-842
GPS2	-889
CYP4F8	-925
GGPS1	-1066
ACSBG1	-1236
CBR4	-1239
STAR	-1244
ACBD5	-1284
ACADM	-1308
PLEKHA2	-1351
ETNK1	-1401
MED28	-1429
MOGAT3	-1460
HILPDA	-1566
MTMR12	-1677
HACD2	-1711
PLEKHA6	-1745
SLC10A1	-1762
CDK8	-1971
HMGCS1	-1972
INPP5K	-2034
MTMR2	-2216
ECHS1	-2265
PIK3R5	-2304
MFSD2A	-2309
OXCT2	-2322
PIP4K2A	-2365
CERS5	-2540
SEC24C	-2569
PI4KA	-2601
OSBP	-2645
DPEP2	-2705
ARV1	-2720
CERS3	-2840
PLA2G4C	-2845
DPEP3	-2894
STARD5	-2943
PLEKHA8	-3080
PHYH	-3231
RXRB	-3276
ACOT7	-3289
CHKB	-3319
PNPLA4	-3322
MTMR1	-3383
CDS1	-3388
CPNE1	-3397
PITPNM3	-3420
PPM1L	-3445
ANGPTL4	-3469
SLC44A5	-3527
GPX2	-3533
MTMR7	-3565
OSBPL10	-3580
NR1H3	-3597
SLC27A5	-3614
PLA2G10	-3617
SC5D	-3695
ACAT2	-3713
PLIN1	-3785
ACP6	-3790
CYP27B1	-3807
CYP24A1	-3820
SLC27A2	-3831
NEU3	-3833
PLD6	-3870
FA2H	-3949
MED1	-4036
INPP5D	-4038
PIK3R4	-4062
STARD4	-4084
KDSR	-4187
SCAP	-4189
SIN3B	-4205
CYP7B1	-4294
PI4KB	-4465
ACBD4	-4503
GDPD1	-4554
CPT1B	-4584
CHD9	-4585
ACOT1	-4622
LGMN	-4644
MCEE	-4724
ARSG	-4773
PITPNM2	-4822
INPP5F	-4865
FAAH2	-4912
PLEKHA5	-4963
GPAT2	-4997
FDX2	-5019
PPARGC1B	-5047
PLEKHA3	-5068
FAAH	-5096
PIK3C2A	-5194
UGT8	-5219
CERK	-5241
CERS4	-5342
ABCB4	-5440
TGS1	-5441
MED30	-5484
LPIN3	-5536
ARSJ	-5542
HSD17B3	-5592
PLPP1	-5711
AHRR	-5763
PLA2G2D	-5777
OSBPL1A	-5816
TRIB3	-5843
MVD	-5850
PRXL2B	-5905
ACSL6	-5913
MED21	-5937
MIGA2	-5952
ORMDL1	-5954
FITM2	-6050
PON2	-6147
FITM1	-6244
AKR1C2	-6258
PPARD	-6394
PI4K2A	-6666
PLA2G4B	-6679
PLAAT3	-6706
ELOVL4	-6768
MED23	-6787
RAN	-6791
ARNTL	-6811
PNPLA7	-6877
GPD1	-6895
PTGES2	-6926
LPIN2	-6935
AMACR	-6980
PITPNB	-7049
CPNE7	-7075
CYP2J2	-7268
MIGA1	-7300
MECR	-7348
ALOX12B	-7374
MED24	-7387
ACSM3	-7398
LPCAT1	-7428
CLOCK	-7460
TM7SF2	-7470
CUBN	-7513
SCD5	-7756
PIP4K2B	-7788
ACER1	-7850
PCCB	-7976
MED29	-7985
PRKAB2	-8172
NRF1	-8183
THEM5	-8249
CYP2D6	-8301
MVK	-8305
INPP5E	-8363
LPCAT4	-8430
SYNJ2	-8511
AGPAT4	-8576
MED10	-8579
PCCA	-8664
MED9	-8812
PEX11A	-8816
SPTSSB	-8818
PRKD2	-8834
INPP4B	-8893
NR1D1	-8980
HELZ2	-9045
HSD17B7	-9066
ETNK2	-9115
MED27	-9191
ASAH2	-9218
SACM1L	-9235
LIPE	-9245
SGPP2	-9332
CYP2E1	-9363
TECR	-9426
PIK3R1	-9505
MLYCD	-9599
INPP4A	-9634
MORC2	-9637
MED15	-9778
CYP2R1	-9918
AGPAT5	-9925
TNFAIP8L1	-9931
ACACB	-9957
PTPN13	-9962
NFYB	-9964
ORMDL3	-9997
MTMR8	-10026
ACOT2	-10127
EPHX2	-10186
ACAD11	-10194
FABP3	-10221
GPAM	-10241
PLPP6	-10392
BDH1	-10419
GPD1L	-10479
SIN3A	-10493
ACSL5	-10518
SBF1	-10530
SLC25A17	-10559
LSS	-10583
INSIG1	-10636
ALOX15	-10676
HSD17B8	-10724
ACOT4	-10733
GDPD5	-10745
SELENOI	-10809
HACD3	-10864
PTGDS	-10886
TIAM2	-10979
DEGS2	-11048
THEM4	-11069
ACBD6	-11092
ARSK	-11166
ACSF2	-11266
PIK3C2B	-11281
PPT2	-11340
PCYT2	-11345
PIP4K2C	-11371
HADH	-11421
LPIN1	-11437
ELOVL6	-11474
MMAA	-11476
BDH2	-11480
TSPOAP1	-11608
DDHD1	-11616
ESYT2	-11660
OXCT1	-11698
OSBPL7	-11742
SMPD4	-11747
HACL1	-11751
ECI2	-11768
DDHD2	-11818
AKR1B1	-11917
PRKACB	-11959
OSBPL3	-11960
CROT	-11973
RORA	-11979
PI4K2B	-11980
CYP2U1	-12000
PIK3R3	-12015
EBP	-12029
SUMF2	-12038
AKR1C3	-12104
AGK	-12120
PLA2G6	-12122
PLEKHA1	-12149
OSBPL5	-12194
SGPP1	-12210
PLAAT4	-12230
SMPD3	-12234
ESYT1	-12237
TNFRSF21	-12254
CYP4F22	-12271
PLD4	-12365

---

Transport of small molecules

Transport of small molecules

	1290
set	Transport of small molecules
setSize	561
pANOVA	1.57e-14
s.dist	0.19
p.adjustANOVA	1.07e-12

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MICU1	9473
CYB5R1	9460
PRKACA	9429
ATP6V0A1	9423
FBXL5	9410
ASPH	9399
SLC1A3	9389
CA1	9380
GNG10	9349
MCU	9320
ATP6V1A	9302
SLC36A1	9292
AQP9	9282
TRPV4	9269
ANO10	9254
ATP6V0D1	9245
PCSK9	9208
BSG	9172
SLC11A1	9169
SLC4A1	9141

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MICU1	9473
CYB5R1	9460
PRKACA	9429
ATP6V0A1	9423
FBXL5	9410
ASPH	9399
SLC1A3	9389
CA1	9380
GNG10	9349
MCU	9320
ATP6V1A	9302
SLC36A1	9292
AQP9	9282
TRPV4	9269
ANO10	9254
ATP6V0D1	9245
PCSK9	9208
BSG	9172
SLC11A1	9169
SLC4A1	9141
ATP6V0C	9127
SLC22A4	9124
TRPM2	9102
FURIN	9075
ATP6V1B2	9057
HBB	9054
ATP6V1D	9047
SLC2A3	9021
CLTC	9000
HBA1	8990
ADCY3	8984
PARL	8958
ERLIN2	8928
DMTN	8924
NCEH1	8922
SLC6A6	8907
OS9	8898
SLC31A1	8874
ERLIN1	8869
SLC22A15	8855
GNG5	8815
SLC16A3	8783
HFE	8777
PCSK6	8740
SLC39A1	8736
RAB11A	8688
FTL	8665
AP2M1	8627
PRKAR1A	8607
CYB5R2	8600
ATP6V0B	8598
ATP6V0E1	8596
ATP6V1C1	8539
SLC44A1	8526
SLC15A3	8517
ALAD	8514
PSMB7	8485
SLCO2B1	8450
SLC8A1	8444
P4HB	8440
CYB5R4	8421
PSMD4	8402
ATP11A	8394
CLTA	8376
SLC39A8	8339
SLCO3A1	8338
SLC27A1	8305
GNB1	8294
HMOX1	8278
PSME3	8251
SOAT1	8231
ATP6AP1	8160
GNB2	8141
SLC43A2	8105
PSMB5	8101
SLC12A6	8097
ATP6V1H	8064
ANO6	8048
ATP2A2	8038
ATP6V1E1	8035
AP2S1	8026
SLC26A6	7982
SLC30A1	7974
SLC9A1	7969
PRKAR1B	7918
GNAS	7909
RAF1	7879
NEDD4L	7875
SLC35D2	7872
VDAC2	7857
PSMD6	7846
SLC24A4	7789
LCN2	7755
SLC8B1	7746
MCOLN1	7740
HDLBP	7702
SLC40A1	7696
BEST1	7678
SLC36A4	7655
SGK3	7646
PSMD9	7620
RUNX1	7529
ATP2C2	7512
SLC9A9	7500
AQP1	7476
SLC4A2	7458
SLC6A9	7452
ABCC4	7434
NR1H2	7415
PSMD2	7411
FXYD6	7391
APOBR	7351
ABCD1	7346
PLTP	7338
GNB4	7336
PSMA1	7329
AQP10	7294
CLCN3	7261
AP2A2	7257
PSMD1	7241
SLC35A1	7225
EMB	7219
TCIRG1	7188
PSMB3	7171
FKBP1B	7154
SLC7A7	7123
TTYH3	7122
PSMA7	7096
MMGT1	7078
OSTM1	7036
BEST3	7024
PSMC1	7021
ATP8B4	6970
SLC22A5	6929
VCP	6886
SEL1L	6847
SLC2A9	6834
AP2A1	6832
CTNS	6817
PSMB6	6813
ATP7B	6800
CLCN5	6792
TPCN2	6751
EIF2S3	6747
PRKAR2B	6741
STOM	6704
TRPM4	6679
PSMF1	6659
UBB	6639
PSMC6	6635
PSMD12	6556
SRI	6554
LIPA	6505
GNG11	6495
RNF185	6491
NEDD8	6482
SAR1B	6479
SLC1A5	6476
ABCB6	6405
RYR2	6400
ATP1B2	6378
SLC28A3	6309
SLC38A2	6297
SLC25A6	6264
PSMD11	6231
LDLR	6183
EIF2S2	6175
PRKAR2A	6166
SLC2A14	6117
ABCA1	6109
ANO8	6099
YME1L1	6069
ATP11B	6064
ABCB10	6018
STEAP3	5996
PSMA6	5970
PSMD7	5963
SCARB1	5962
PSMD13	5948
APOA2	5879
ATP6V1F	5878
PSMD8	5757
PEX19	5750
ATP6V1E2	5730
ABCC3	5717
ADD1	5704
CYBRD1	5661
ABCC6	5615
ATP9B	5614
SLC35B3	5546
SLC24A3	5480
NPC2	5458
BSND	5426
UNC79	5414
SLC24A2	5374
SLC22A16	5373
PSMA2	5339
ADCY4	5270
IREB2	5231
WNK1	5224
SLC3A2	5222
TPCN1	5221
SLC29A3	5197
ATP9A	5106
SLC16A7	5083
SLCO4A1	5037
CLCN4	5036
SLC9A8	5001
LRRC8D	4999
SLC17A5	4989
SLC66A1	4965
ABCD3	4933
SLC5A9	4930
FTH1	4902
SLC39A7	4879
ATP2C1	4865
PCSK5	4863
RAB11FIP2	4818
SLC9A6	4781
SLC22A1	4716
ATP8B3	4711
CLCN1	4687
PSMD3	4618
SGK1	4595
TRPM6	4515
SLC39A3	4505
SLC39A4	4464
ANO5	4463
SLC16A1	4455
UBC	4439
SEM1	4348
VDAC1	4347
GNG8	4296
SKP1	4287
EIF2S1	4279
NIPA2	4203
SLC22A18	4112
PSMB2	4084
CUTC	3944
ATP6V1G1	3931
ADD3	3735
SLC15A4	3724
SLC50A1	3692
TSC22D3	3680
ALB	3668
CA2	3570
SLC15A2	3556
SLC35B4	3472
PSMD5	3426
SLC6A12	3414
PSMB1	3374
NIPAL1	3335
SLC35A2	3255
SLCO4C1	3212
ATP13A2	3194
ATP11C	3159
LRRC8B	3157
BEST2	3141
ABCA7	3077
ABCG8	3056
DERL2	3041
SLC7A5	3012
CETP	3003
SLC2A13	2987
MBTPS1	2966
SLC12A1	2870
SLC12A4	2845
CA4	2826
SLC25A18	2815
ATP1A1	2813
ATP10B	2755
SLC35C1	2750
SLC44A2	2700
MAGT1	2613
PSMD14	2611
PSMC2	2598
SLC25A29	2580
LPL	2545
PSMB4	2523
SLC27A4	2479
ABCC5	2477
ATP10D	2433
CFTR	2416
CLCN6	2232
PSMC3	1976
CLCN7	1943
CAMK2G	1921
SLC7A8	1916
SLC8A3	1886
SLC46A1	1882
NIPAL2	1795
WNK2	1613
SLC16A8	1608
PSMD10	1559
TFRC	1524
SLC29A1	1428
TRPC4AP	1263
SLC34A2	1253
RSC1A1	1209
UBA52	1121
TF	1102
ATP1A4	922
SLC17A7	919
GNG3	890
SLC5A12	836
SLC25A5	826
TRPM3	797
ERLEC1	698
ATP7A	694
LIPC	625
SLC7A9	622
LRRC8C	594
ABCC1	576
GNB5	512
VDAC3	436
AHCYL2	425
AVPR2	291
SLC18A2	286
BMP1	268
SLC11A2	260
SMDT1	254
APOE	218
ADCY9	123
LCN15	93
MBTPS2	83
SLC30A6	-3
ABCG2	-77
PHB2	-166
SLC28A2	-181
SCNN1A	-222
NIPAL4	-379
APOD	-426
SLC30A2	-444
ARL2	-565
UNC80	-568
PSMA4	-616
SLC1A2	-728
PMPCB	-803
CLCN2	-812
MICU2	-817
PSMC5	-863
LCAT	-884
TTYH1	-893
ATP2A3	-914
SLC6A1	-949
LIPG	-1012
SLC1A6	-1034
ABCB8	-1115
SLC36A2	-1307
ATP1B3	-1347
SLC5A11	-1350
SLC13A5	-1420
GLRX3	-1479
CP	-1561
SLC34A1	-1602
ADCY6	-1608
ABCA9	-1819
ABCB7	-1842
TRPC6	-1935
ABCC2	-2079
CALM1	-2081
SLC33A1	-2142
GNG4	-2154
ATP6V1C2	-2219
ABCB9	-2228
AQP11	-2381
GNB3	-2397
ANO7	-2410
SLC12A7	-2422
TRPM8	-2445
SLC30A5	-2461
SLC29A4	-2485
ABCA6	-2612
SLC2A6	-2676
SLC22A17	-2703
AP2B1	-2709
SOAT2	-2861
SLC26A2	-2893
ADCY2	-2896
SLC13A4	-2986
PHB	-2995
MFSD4B	-3031
PSMB8	-3076
SLC47A1	-3233
ADCY7	-3286
ASIC1	-3426
ZDHHC8	-3451
ANGPTL4	-3469
MCUB	-3477
TRPM5	-3491
SLC44A5	-3527
NR1H3	-3597
MYLIP	-3991
STOML2	-4000
SLC14A2	-4001
KCNJ11	-4105
AMN	-4361
VLDLR	-4385
SLC30A7	-4455
TTYH2	-4458
LETM1	-4573
SLC43A1	-4611
ATP2A1	-4667
MCOLN3	-4692
SLC16A10	-4715
SLC5A2	-4725
ABCC9	-4745
ATP8A2	-4798
TRPV6	-4904
ABCC10	-4930
ATP2B4	-5030
ATP8B1	-5033
SLC4A5	-5062
GNG7	-5198
WNK3	-5232
SLC6A20	-5271
PSMA3	-5285
SLC5A5	-5330
FXYD1	-5429
ABCB4	-5440
TRPV2	-5458
SLC2A10	-5478
RYR1	-5495
ATP13A1	-5530
ADD2	-5586
SLC5A6	-5629
SCNN1D	-5715
SLC7A11	-5719
PSMB10	-5735
FXYD2	-5748
SLC38A5	-5797
SLC2A12	-5930
PSMA5	-6053
SLC9B1	-6075
PSME4	-6087
PMPCA	-6127
PDZD11	-6288
AQP7	-6377
SGK2	-6388
RNF5	-6413
SLC39A5	-6434
SLC7A1	-6472
SLC25A22	-6553
CAND1	-6554
MRS2	-6620
SLC7A6	-6690
ARL2BP	-6734
SLC14A1	-6749
SLC47A2	-6833
SLC39A14	-6854
SLC35D1	-6904
CLIC2	-6930
RPS27A	-6938
SLC2A11	-7005
SLC9A7	-7073
ASIC3	-7185
FXYD7	-7230
MICU3	-7286
LSR	-7320
SLC34A3	-7335
SLC26A11	-7413
TRPM7	-7431
DERL3	-7467
CUBN	-7513
PSMA8	-7606
SLC4A10	-7713
SLC39A6	-7717
SLC45A3	-7791
GNG2	-7795
SLC9A5	-7799
ATP13A4	-7878
ABCG1	-7961
LMF2	-8018
LRRC8A	-8132
SLC26A1	-8174
ADCY5	-8235
ATP2B1	-8286
SLC3A1	-8302
FLVCR1	-8306
SLC9A3	-8347
ACO1	-8450
ABCA5	-8681
BEST4	-8728
CES3	-8917
DERL1	-8963
FXYD3	-8981
ABCA10	-9007
ATP1B1	-9118
PSMC4	-9127
ANO9	-9130
MYO5B	-9138
LMF1	-9157
SLC35A3	-9305
LDLRAP1	-9326
TRPC3	-9343
SLC5A10	-9419
ATP6V1G2	-9515
ABCF1	-9531
TRPV1	-9543
SLC1A7	-9612
SLC29A2	-9723
TRPC1	-9736
AQP3	-9760
TFR2	-9789
A2M	-9870
RYR3	-9953
PSME1	-9991
SLC4A8	-10101
WWP1	-10106
SLC35B2	-10225
SLC25A10	-10239
SLC39A10	-10306
NIPAL3	-10316
PSME2	-10336
ABCA2	-10376
SPG7	-10555
CYB5RL	-10762
AFG3L2	-10807
ATP8B2	-10811
LCN12	-10869
TRPV3	-10996
SLC24A1	-11057
SLC13A3	-11108
ABCD2	-11160
SLC1A4	-11174
SLC5A3	-11186
SLC2A1	-11236
NIPA1	-11316
PSMB9	-11324
CUL1	-11330
SLC12A2	-11346
SLC12A3	-11355
SLC9B2	-11358
SLC38A1	-11417
SLC20A1	-11418
AKAP1	-11442
SLC41A1	-11497
ATP1A3	-11543
ATP6V0E2	-11555
MCOLN2	-11638
SLC18A1	-11684
SLC4A4	-11735
SLC2A8	-11749
ABCA3	-11756
CAMK2D	-11816
HMOX2	-11819
SLC20A2	-11823
ATP8A1	-11842
SLC25A4	-11858
ANKH	-11883
SLC4A7	-11915
PRKACB	-11959
PEX3	-12083
GNGT2	-12086
ATP6V0A2	-12211
NPC1	-12217
ATP10A	-12218
ABCB1	-12224
SLC25A26	-12252
SLC4A3	-12321
SLC41A2	-12379

---

Toll Like Receptor 4 (TLR4) Cascade

Toll Like Receptor 4 (TLR4) Cascade

	1241
set	Toll Like Receptor 4 (TLR4) Cascade
setSize	121
pANOVA	3.21e-14
s.dist	0.399
p.adjustANOVA	2.09e-12

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A12	9515
CD36	9444
ITGAM	9398
NKIRAS2	9353
DUSP3	9280
UBE2D1	9187
APP	9177
IRAK3	9107
MAPK14	9104
TLR2	9103
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
ITGB2	8942
TLR1	8932
MAP2K6	8887
TLR6	8840
LY96	8795
MAP2K3	8748

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A12	9515
CD36	9444
ITGAM	9398
NKIRAS2	9353
DUSP3	9280
UBE2D1	9187
APP	9177
IRAK3	9107
MAPK14	9104
TLR2	9103
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
ITGB2	8942
TLR1	8932
MAP2K6	8887
TLR6	8840
LY96	8795
MAP2K3	8748
UBE2D3	8640
NOD2	8442
MAPKAPK3	8382
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966
PELI3	7716
PPP2CB	7712
RPS6KA1	7695
LY86	7667
TANK	7502
MAPK1	7493
BTK	7206
DNM3	7045
TAB2	6964
MAP2K4	6866
NFKBIA	6807
PELI1	6715
BPI	6666
UBB	6639
TICAM2	6335
TICAM1	6307
NFKB1	6277
FBXW11	6196
MAP3K8	6160
IRAK1	6131
DNM2	6089
ATF1	5706
TAB1	5681
FADD	5641
TIRAP	5640
UBE2V1	5637
TNIP2	5552
FOS	5460
IKBKG	5377
PTPN11	5314
MAP3K1	5121
PLCG2	5006
ECSIT	4918
IKBKE	4715
BIRC2	4692
UBE2D2	4657
PPP2R1A	4589
UBC	4439
DUSP6	4357
MAPK10	4325
SKP1	4287
RIPK3	4217
MAPKAPK2	4054
SOCS1	3947
MAPK11	3826
JUN	3722
DNM1	3587
TBK1	3229
TAB3	3160
RPS6KA2	3087
RPS6KA3	2973
PPP2R5D	2421
MAP3K7	2395
ATF2	2085
UBE2N	1936
MAP2K7	1654
AGER	1294
VRK3	1281
UBA52	1121
ELK1	1040
RIPK2	1025
NKIRAS1	375
NFKBIB	-152
TRAF6	-229
PPP2R1B	-241
HMGB1	-252
MEF2C	-293
CD180	-600
NFKB2	-1165
MAPK7	-1337
CREB1	-1378
RELA	-1803
DUSP7	-3211
BTRC	-4924
IKBKB	-5386
S100B	-5457
TRAF3	-5576
DUSP4	-6287
RPS27A	-6938
MAPK9	-7068
IRF3	-8517
IRF7	-8657
MAPK8	-9428
IRAK2	-9548
SIGIRR	-10752
RIPK1	-11074
BIRC3	-11125
CUL1	-11330
CASP8	-11336
RPS6KA5	-11594
SARM1	-12134
PTPN4	-12220
NOD1	-12263

---

rRNA processing

rRNA processing

	1356
set	rRNA processing
setSize	219
pANOVA	2.4e-13
s.dist	-0.287
p.adjustANOVA	1.49e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LAS1L	-12267
NAT10	-11952
ELAC2	-11761
NOP56	-11750
RBM28	-11671
BMS1	-11670
DKC1	-11637
PDCD11	-11518
UTP4	-11494
EXOSC8	-11456
EXOSC10	-11379
TFB1M	-11344
DDX47	-11299
EXOSC2	-11072
IMP4	-10976
WDR46	-10970
PELP1	-10928
NOL6	-10908
MTERF4	-10891
NOP14	-10866

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LAS1L	-12267
NAT10	-11952
ELAC2	-11761
NOP56	-11750
RBM28	-11671
BMS1	-11670
DKC1	-11637
PDCD11	-11518
UTP4	-11494
EXOSC8	-11456
EXOSC10	-11379
TFB1M	-11344
DDX47	-11299
EXOSC2	-11072
IMP4	-10976
WDR46	-10970
PELP1	-10928
NOL6	-10908
MTERF4	-10891
NOP14	-10866
EXOSC7	-10631
UTP15	-10603
UTP20	-10529
MRM1	-10517
NOL11	-10471
HEATR1	-10345
NOB1	-10320
CSNK1E	-10298
EXOSC9	-10250
NOL9	-10224
EMG1	-10189
FBL	-10188
RRP9	-10080
NOP2	-9952
NOP58	-9951
WDR75	-9921
EXOSC6	-9839
THUMPD1	-9802
TEX10	-9765
RPS27	-9756
TSR1	-9731
RPL23A	-9567
IMP3	-9459
NCL	-9269
RPS20	-8886
RPL39L	-8805
KRR1	-8623
RPL3	-8561
GNL3	-8489
DHX37	-8267
RPP25	-8247
RPL13A	-8212
RPP30	-8101
RPL35	-8092
DIMT1	-7988
RPS29	-7940
MPHOSPH10	-7790
RPS18	-7744
WDR43	-7687
MRM3	-7522
RPL36A	-7376
RPS11	-7243
MT-TL2	-7170
RPLP2	-7087
RPP38	-7076
RPL12	-7053
RPL30	-7020
RPS19	-6965
GAR1	-6941
RPS27A	-6938
SNU13	-6871
RPL41	-6866
PNO1	-6861
RPL34	-6802
RPL14	-6710
RPL32	-6709
RPL10A	-6686
WDR3	-6619
RPL26	-6612
MT-ND2	-6560
RPL10	-6534
RPL21	-6458
RPL37	-6375
RPS25	-6365
RPSA	-6323
RPS23	-6292
RPS4X	-6285
RPL19	-6281
RPL11	-6261
RPL27A	-6257
RPS17	-6247
RPS6	-6160
RPL18A	-6070
RPL35A	-6015
RPS12	-5987
RPS3	-5914
NIP7	-5876
RPL38	-5840
RPL24	-5799
RPS10	-5793
RPS15A	-5742
RPS5	-5691
DCAF13	-5572
NOC4L	-5483
RPS14	-5463
RPL17	-5431
RPP21	-5355
RPL36	-5287
BOP1	-5212
RPL18	-5080
RPS7	-4968
RPP40	-4835
NSUN4	-4799
RPL22	-4740
RPL5	-4728
RPS28	-4713
RPS3A	-4694
RPS16	-4669
EXOSC5	-4577
RPL31	-4541
UTP6	-4507
RPS2	-4499
TRMT10C	-4481
BYSL	-4461
DIS3	-4322
LTV1	-4296
EBNA1BP2	-4097
RPS21	-4079
FTSJ3	-4022
RPL37A	-3946
WDR36	-3945
RIOK1	-3814
RPS15	-3673
RPL7A	-3665
MT-TV	-3652
MT-ND3	-3649
MT-ND1	-3616
RPL29	-3611
RPL4	-3582
NHP2	-3471
TBL3	-3437
RPL13	-3431
RPL6	-3354
RPL23	-3314
RRP1	-3084
MT-ATP8	-3067
RPL39	-3006
MT-TL1	-2976
UTP3	-2903
RPL27	-2855
RRP7A	-2806
MT-TF	-2754
MTREX	-2638
SNORD3A	-2539
WDR18	-2310
MT-CYB	-2254
MT-ND5	-2166
MT-ATP6	-2096
RPS8	-2083
UTP14C	-2073
PES1	-2033
MT-ND4L	-2023
RPL7	-1955
RPL9	-1872
UTP14A	-1821
RPS13	-1749
RRP36	-1672
RPL22L1	-1619
MT-TM	-1516
RPL28	-1462
RPS26	-1430
PWP2	-1207
RPL8	-1187
RPLP0	-1000
EXOSC1	-991
RPL15	-963
RCL1	-757
FAU	-362
MT-RNR1	-300
RPS24	-263
RPLP1	19
RPL36AL	32
MT-CO3	40
MT-CO2	48
RPS4Y1	424
DDX52	454
EXOSC3	509
MT-CO1	684
TRMT112	738
MT-ND4	840
RIOK2	934
UBA52	1121
MRM2	1460
RPS27L	2061
MT-RNR2	2112
MPHOSPH6	2181
CSNK1D	2390
SENP3	2994
RPP14	3005
DDX21	3113
PRORP	3390
C1D	3516
ISG20L2	3775
TSR3	3846
HSD17B10	4182
FCF1	4472
RPL3L	4503
UTP11	4631
DDX49	4872
NOL12	4944
UTP18	5114
WDR12	5217
RPS9	5421
ERI1	5541
RPL26L1	7176
EXOSC4	7600
NOP10	8332
RIOK3	8765
XRN2	9400

---

ER to Golgi Anterograde Transport

ER to Golgi Anterograde Transport

	328
set	ER to Golgi Anterograde Transport
setSize	129
pANOVA	2.87e-13
s.dist	0.372
p.adjustANOVA	1.53e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
F5	9485
ARF4	9191
SERPINA1	9168
DCTN2	9157
SPTB	9154
CD55	9145
KDELR1	9142
ARF1	9064
RAB1A	9052
CTSZ	8975
TGFA	8889
NSF	8829
ANK1	8771
CAPZA2	8597
DCTN4	8387
COPA	8366
RAB1B	8313
CAPZA1	8135
SEC24D	8115
CAPZB	8015

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
F5	9485
ARF4	9191
SERPINA1	9168
DCTN2	9157
SPTB	9154
CD55	9145
KDELR1	9142
ARF1	9064
RAB1A	9052
CTSZ	8975
TGFA	8889
NSF	8829
ANK1	8771
CAPZA2	8597
DCTN4	8387
COPA	8366
RAB1B	8313
CAPZA1	8135
SEC24D	8115
CAPZB	8015
TMED7	7950
COPB2	7902
ARF5	7885
TRAPPC1	7806
CNIH1	7779
DYNC1I2	7735
ARF3	7732
KDELR2	7728
SEC24A	7660
ACTR10	7605
SPTA1	7595
COPG2	7594
COPG1	7509
SEC23A	7335
COPB1	7321
DCTN6	7300
TMED9	7167
STX5	7166
TFG	7160
TRAPPC3	7114
MCFD2	7099
LMAN2	7080
F8	7022
ACTR1A	7002
DYNC1LI1	6941
LMAN2L	6937
COPE	6896
PPP6C	6819
GORASP1	6606
SAR1B	6479
PREB	6368
COL7A1	6304
GOLGA2	6203
TMED2	6052
DCTN3	5994
AREG	5977
DYNLL1	5952
SEC22B	5873
CD59	5859
SEC13	5748
ARCN1	5580
MIA2	5574
TMEM115	5508
TRAPPC9	5333
PPP6R1	5263
YKT6	5205
TRAPPC5	5191
DCTN1	5078
SEC16A	4619
DYNC1LI2	4273
COG7	4269
DYNC1I1	4187
USO1	4154
TRAPPC6B	4147
NAPG	4139
COPZ1	4035
ARFGAP3	3714
SEC24B	3608
SCFD1	3525
PPP6R3	3261
TMED3	2720
CSNK1D	2390
CTSC	2326
NAPA	1432
SEC31A	1099
CNIH2	654
SEC16B	330
TMED10	323
COG4	-6
TBC1D20	-18
GOSR1	-182
COG8	-346
SEC23IP	-468
BET1	-594
GOSR2	-1456
ARFGAP1	-1942
KDELR3	-2117
TRAPPC2L	-2299
SEC24C	-2569
NAPB	-2780
COG5	-3259
SPTBN5	-3531
DYNLL2	-3980
DCTN5	-4086
SEC22C	-4248
GBF1	-4290
ANK3	-4919
SEC22A	-5052
SPTBN2	-5129
GOLGB1	-5370
COG3	-5426
ARFGAP2	-5786
COG6	-5811
MIA3	-6245
ANKRD28	-6250
TRAPPC4	-6712
BET1L	-7405
DYNC1H1	-7685
SPTBN1	-7764
COG2	-7917
TRAPPC2	-8704
CNIH3	-9011
TRAPPC10	-9369
LMAN1	-10630
COPZ2	-10863
TRAPPC6A	-10917
STX17	-11006
SPTAN1	-11426
COG1	-12125

---

MyD88:MAL(TIRAP) cascade initiated on plasma membrane

MyD88:MAL(TIRAP) cascade initiated on plasma membrane

	690
set	MyD88:MAL(TIRAP) cascade initiated on plasma membrane
setSize	92
pANOVA	3.03e-13
s.dist	0.44
p.adjustANOVA	1.53e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A12	9515
CD36	9444
NKIRAS2	9353
DUSP3	9280
APP	9177
IRAK3	9107
MAPK14	9104
TLR2	9103
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
TLR1	8932
MAP2K6	8887
TLR6	8840
LY96	8795
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A12	9515
CD36	9444
NKIRAS2	9353
DUSP3	9280
APP	9177
IRAK3	9107
MAPK14	9104
TLR2	9103
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
TLR1	8932
MAP2K6	8887
TLR6	8840
LY96	8795
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966
PELI3	7716
PPP2CB	7712
RPS6KA1	7695
MAPK1	7493
BTK	7206
TAB2	6964
MAP2K4	6866
NFKBIA	6807
PELI1	6715
UBB	6639
NFKB1	6277
FBXW11	6196
MAP3K8	6160
IRAK1	6131
ATF1	5706
TAB1	5681
TIRAP	5640
UBE2V1	5637
TNIP2	5552
FOS	5460
IKBKG	5377
MAP3K1	5121
ECSIT	4918
PPP2R1A	4589
UBC	4439
DUSP6	4357
MAPK10	4325
SKP1	4287
MAPKAPK2	4054
SOCS1	3947
MAPK11	3826
JUN	3722
TAB3	3160
RPS6KA2	3087
RPS6KA3	2973
PPP2R5D	2421
MAP3K7	2395
ATF2	2085
UBE2N	1936
MAP2K7	1654
AGER	1294
VRK3	1281
UBA52	1121
ELK1	1040
RIPK2	1025
NKIRAS1	375
NFKBIB	-152
TRAF6	-229
PPP2R1B	-241
HMGB1	-252
MEF2C	-293
NFKB2	-1165
MAPK7	-1337
CREB1	-1378
RELA	-1803
DUSP7	-3211
BTRC	-4924
IKBKB	-5386
S100B	-5457
DUSP4	-6287
RPS27A	-6938
MAPK9	-7068
MAPK8	-9428
IRAK2	-9548
SIGIRR	-10752
CUL1	-11330
RPS6KA5	-11594
NOD1	-12263

---

Toll Like Receptor 2 (TLR2) Cascade

Toll Like Receptor 2 (TLR2) Cascade

	1239
set	Toll Like Receptor 2 (TLR2) Cascade
setSize	92
pANOVA	3.03e-13
s.dist	0.44
p.adjustANOVA	1.53e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A12	9515
CD36	9444
NKIRAS2	9353
DUSP3	9280
APP	9177
IRAK3	9107
MAPK14	9104
TLR2	9103
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
TLR1	8932
MAP2K6	8887
TLR6	8840
LY96	8795
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A12	9515
CD36	9444
NKIRAS2	9353
DUSP3	9280
APP	9177
IRAK3	9107
MAPK14	9104
TLR2	9103
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
TLR1	8932
MAP2K6	8887
TLR6	8840
LY96	8795
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966
PELI3	7716
PPP2CB	7712
RPS6KA1	7695
MAPK1	7493
BTK	7206
TAB2	6964
MAP2K4	6866
NFKBIA	6807
PELI1	6715
UBB	6639
NFKB1	6277
FBXW11	6196
MAP3K8	6160
IRAK1	6131
ATF1	5706
TAB1	5681
TIRAP	5640
UBE2V1	5637
TNIP2	5552
FOS	5460
IKBKG	5377
MAP3K1	5121
ECSIT	4918
PPP2R1A	4589
UBC	4439
DUSP6	4357
MAPK10	4325
SKP1	4287
MAPKAPK2	4054
SOCS1	3947
MAPK11	3826
JUN	3722
TAB3	3160
RPS6KA2	3087
RPS6KA3	2973
PPP2R5D	2421
MAP3K7	2395
ATF2	2085
UBE2N	1936
MAP2K7	1654
AGER	1294
VRK3	1281
UBA52	1121
ELK1	1040
RIPK2	1025
NKIRAS1	375
NFKBIB	-152
TRAF6	-229
PPP2R1B	-241
HMGB1	-252
MEF2C	-293
NFKB2	-1165
MAPK7	-1337
CREB1	-1378
RELA	-1803
DUSP7	-3211
BTRC	-4924
IKBKB	-5386
S100B	-5457
DUSP4	-6287
RPS27A	-6938
MAPK9	-7068
MAPK8	-9428
IRAK2	-9548
SIGIRR	-10752
CUL1	-11330
RPS6KA5	-11594
NOD1	-12263

---

Toll Like Receptor TLR1:TLR2 Cascade

Toll Like Receptor TLR1:TLR2 Cascade

	1245
set	Toll Like Receptor TLR1:TLR2 Cascade
setSize	92
pANOVA	3.03e-13
s.dist	0.44
p.adjustANOVA	1.53e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A12	9515
CD36	9444
NKIRAS2	9353
DUSP3	9280
APP	9177
IRAK3	9107
MAPK14	9104
TLR2	9103
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
TLR1	8932
MAP2K6	8887
TLR6	8840
LY96	8795
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A12	9515
CD36	9444
NKIRAS2	9353
DUSP3	9280
APP	9177
IRAK3	9107
MAPK14	9104
TLR2	9103
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
TLR1	8932
MAP2K6	8887
TLR6	8840
LY96	8795
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966
PELI3	7716
PPP2CB	7712
RPS6KA1	7695
MAPK1	7493
BTK	7206
TAB2	6964
MAP2K4	6866
NFKBIA	6807
PELI1	6715
UBB	6639
NFKB1	6277
FBXW11	6196
MAP3K8	6160
IRAK1	6131
ATF1	5706
TAB1	5681
TIRAP	5640
UBE2V1	5637
TNIP2	5552
FOS	5460
IKBKG	5377
MAP3K1	5121
ECSIT	4918
PPP2R1A	4589
UBC	4439
DUSP6	4357
MAPK10	4325
SKP1	4287
MAPKAPK2	4054
SOCS1	3947
MAPK11	3826
JUN	3722
TAB3	3160
RPS6KA2	3087
RPS6KA3	2973
PPP2R5D	2421
MAP3K7	2395
ATF2	2085
UBE2N	1936
MAP2K7	1654
AGER	1294
VRK3	1281
UBA52	1121
ELK1	1040
RIPK2	1025
NKIRAS1	375
NFKBIB	-152
TRAF6	-229
PPP2R1B	-241
HMGB1	-252
MEF2C	-293
NFKB2	-1165
MAPK7	-1337
CREB1	-1378
RELA	-1803
DUSP7	-3211
BTRC	-4924
IKBKB	-5386
S100B	-5457
DUSP4	-6287
RPS27A	-6938
MAPK9	-7068
MAPK8	-9428
IRAK2	-9548
SIGIRR	-10752
CUL1	-11330
RPS6KA5	-11594
NOD1	-12263

---

Toll Like Receptor TLR6:TLR2 Cascade

Toll Like Receptor TLR6:TLR2 Cascade

	1246
set	Toll Like Receptor TLR6:TLR2 Cascade
setSize	92
pANOVA	3.03e-13
s.dist	0.44
p.adjustANOVA	1.53e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A12	9515
CD36	9444
NKIRAS2	9353
DUSP3	9280
APP	9177
IRAK3	9107
MAPK14	9104
TLR2	9103
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
TLR1	8932
MAP2K6	8887
TLR6	8840
LY96	8795
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A12	9515
CD36	9444
NKIRAS2	9353
DUSP3	9280
APP	9177
IRAK3	9107
MAPK14	9104
TLR2	9103
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
TLR1	8932
MAP2K6	8887
TLR6	8840
LY96	8795
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966
PELI3	7716
PPP2CB	7712
RPS6KA1	7695
MAPK1	7493
BTK	7206
TAB2	6964
MAP2K4	6866
NFKBIA	6807
PELI1	6715
UBB	6639
NFKB1	6277
FBXW11	6196
MAP3K8	6160
IRAK1	6131
ATF1	5706
TAB1	5681
TIRAP	5640
UBE2V1	5637
TNIP2	5552
FOS	5460
IKBKG	5377
MAP3K1	5121
ECSIT	4918
PPP2R1A	4589
UBC	4439
DUSP6	4357
MAPK10	4325
SKP1	4287
MAPKAPK2	4054
SOCS1	3947
MAPK11	3826
JUN	3722
TAB3	3160
RPS6KA2	3087
RPS6KA3	2973
PPP2R5D	2421
MAP3K7	2395
ATF2	2085
UBE2N	1936
MAP2K7	1654
AGER	1294
VRK3	1281
UBA52	1121
ELK1	1040
RIPK2	1025
NKIRAS1	375
NFKBIB	-152
TRAF6	-229
PPP2R1B	-241
HMGB1	-252
MEF2C	-293
NFKB2	-1165
MAPK7	-1337
CREB1	-1378
RELA	-1803
DUSP7	-3211
BTRC	-4924
IKBKB	-5386
S100B	-5457
DUSP4	-6287
RPS27A	-6938
MAPK9	-7068
MAPK8	-9428
IRAK2	-9548
SIGIRR	-10752
CUL1	-11330
RPS6KA5	-11594
NOD1	-12263

---

rRNA processing in the nucleus and cytosol

rRNA processing in the nucleus and cytosol

	1358
set	rRNA processing in the nucleus and cytosol
setSize	190
pANOVA	3.58e-13
s.dist	-0.306
p.adjustANOVA	1.75e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LAS1L	-12267
NAT10	-11952
NOP56	-11750
RBM28	-11671
BMS1	-11670
DKC1	-11637
PDCD11	-11518
UTP4	-11494
EXOSC8	-11456
EXOSC10	-11379
DDX47	-11299
EXOSC2	-11072
IMP4	-10976
WDR46	-10970
PELP1	-10928
NOL6	-10908
NOP14	-10866
EXOSC7	-10631
UTP15	-10603
UTP20	-10529

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LAS1L	-12267
NAT10	-11952
NOP56	-11750
RBM28	-11671
BMS1	-11670
DKC1	-11637
PDCD11	-11518
UTP4	-11494
EXOSC8	-11456
EXOSC10	-11379
DDX47	-11299
EXOSC2	-11072
IMP4	-10976
WDR46	-10970
PELP1	-10928
NOL6	-10908
NOP14	-10866
EXOSC7	-10631
UTP15	-10603
UTP20	-10529
NOL11	-10471
HEATR1	-10345
NOB1	-10320
CSNK1E	-10298
EXOSC9	-10250
NOL9	-10224
EMG1	-10189
FBL	-10188
RRP9	-10080
NOP2	-9952
NOP58	-9951
WDR75	-9921
EXOSC6	-9839
THUMPD1	-9802
TEX10	-9765
RPS27	-9756
TSR1	-9731
RPL23A	-9567
IMP3	-9459
NCL	-9269
RPS20	-8886
RPL39L	-8805
KRR1	-8623
RPL3	-8561
GNL3	-8489
DHX37	-8267
RPP25	-8247
RPL13A	-8212
RPP30	-8101
RPL35	-8092
DIMT1	-7988
RPS29	-7940
MPHOSPH10	-7790
RPS18	-7744
WDR43	-7687
RPL36A	-7376
RPS11	-7243
RPLP2	-7087
RPP38	-7076
RPL12	-7053
RPL30	-7020
RPS19	-6965
GAR1	-6941
RPS27A	-6938
SNU13	-6871
RPL41	-6866
PNO1	-6861
RPL34	-6802
RPL14	-6710
RPL32	-6709
RPL10A	-6686
WDR3	-6619
RPL26	-6612
RPL10	-6534
RPL21	-6458
RPL37	-6375
RPS25	-6365
RPSA	-6323
RPS23	-6292
RPS4X	-6285
RPL19	-6281
RPL11	-6261
RPL27A	-6257
RPS17	-6247
RPS6	-6160
RPL18A	-6070
RPL35A	-6015
RPS12	-5987
RPS3	-5914
NIP7	-5876
RPL38	-5840
RPL24	-5799
RPS10	-5793
RPS15A	-5742
RPS5	-5691
DCAF13	-5572
NOC4L	-5483
RPS14	-5463
RPL17	-5431
RPP21	-5355
RPL36	-5287
BOP1	-5212
RPL18	-5080
RPS7	-4968
RPP40	-4835
RPL22	-4740
RPL5	-4728
RPS28	-4713
RPS3A	-4694
RPS16	-4669
EXOSC5	-4577
RPL31	-4541
UTP6	-4507
RPS2	-4499
BYSL	-4461
DIS3	-4322
LTV1	-4296
EBNA1BP2	-4097
RPS21	-4079
FTSJ3	-4022
RPL37A	-3946
WDR36	-3945
RIOK1	-3814
RPS15	-3673
RPL7A	-3665
RPL29	-3611
RPL4	-3582
NHP2	-3471
TBL3	-3437
RPL13	-3431
RPL6	-3354
RPL23	-3314
RRP1	-3084
RPL39	-3006
UTP3	-2903
RPL27	-2855
RRP7A	-2806
MTREX	-2638
SNORD3A	-2539
WDR18	-2310
RPS8	-2083
UTP14C	-2073
PES1	-2033
RPL7	-1955
RPL9	-1872
UTP14A	-1821
RPS13	-1749
RRP36	-1672
RPL22L1	-1619
RPL28	-1462
RPS26	-1430
PWP2	-1207
RPL8	-1187
RPLP0	-1000
EXOSC1	-991
RPL15	-963
RCL1	-757
FAU	-362
RPS24	-263
RPLP1	19
RPL36AL	32
RPS4Y1	424
DDX52	454
EXOSC3	509
TRMT112	738
RIOK2	934
UBA52	1121
RPS27L	2061
MPHOSPH6	2181
CSNK1D	2390
SENP3	2994
RPP14	3005
DDX21	3113
C1D	3516
ISG20L2	3775
TSR3	3846
FCF1	4472
RPL3L	4503
UTP11	4631
DDX49	4872
NOL12	4944
UTP18	5114
WDR12	5217
RPS9	5421
ERI1	5541
RPL26L1	7176
EXOSC4	7600
NOP10	8332
RIOK3	8765
XRN2	9400

---

Signaling by NOTCH

Signaling by NOTCH

	1110
set	Signaling by NOTCH
setSize	183
pANOVA	3.84e-13
s.dist	0.311
p.adjustANOVA	1.81e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NUMB	9414
H2AJ	9374
TACC3	9331
H2BC21	9283
NCSTN	9186
FURIN	9075
AGO4	9070
H2BC12	9051
HDAC4	8960
MAML3	8957
ADAM10	8791
RBPJ	8770
JAG1	8743
H3-3A	8661
TLE3	8558
ARRB2	8490
PSMB7	8485
TFDP1	8470
PSMD4	8402
PSME3	8251

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NUMB	9414.0
H2AJ	9374.0
TACC3	9331.0
H2BC21	9283.0
NCSTN	9186.0
FURIN	9075.0
AGO4	9070.0
H2BC12	9051.0
HDAC4	8960.0
MAML3	8957.0
ADAM10	8791.0
RBPJ	8770.0
JAG1	8743.0
H3-3A	8661.0
TLE3	8558.0
ARRB2	8490.0
PSMB7	8485.0
TFDP1	8470.0
PSMD4	8402.0
PSME3	8251.0
EGF	8179.0
RAB6A	8148.0
ADAM17	8110.0
PSMB5	8101.0
ATP2A2	8038.0
WWP2	8013.0
H2BC5	8003.0
NCOR2	7985.0
PSEN1	7961.0
H2AC6	7934.0
H2BC11	7912.0
NOTCH3	7899.0
TBL1X	7887.0
PSMD6	7846.0
PSMD9	7620.0
RUNX1	7529.0
PTCRA	7507.0
PLXND1	7475.0
HIF1A	7436.0
PSMD2	7411.0
H2BC4	7389.0
PSMA1	7329.0
H2BC17	7285.0
PSMD1	7241.0
RFNG	7233.0
PSMB3	7171.0
PSMA7	7096.0
PSMC1	7021.0
TLE4	6854.0
SEL1L	6847.0
PSMB6	6813.0
DTX2	6754.0
ST3GAL6	6701.0
H3C15	6699.5
PSMF1	6659.0
E2F3	6650.0
UBB	6639.0
PSMC6	6635.0
PSMD12	6556.0
E2F1	6343.0
APH1B	6280.0
PSMD11	6231.0
SIRT6	6214.0
DTX4	6156.0
EP300	6129.0
HDAC7	6122.0
TMED2	6052.0
H2AZ1	6036.0
PSMA6	5970.0
PSMD7	5963.0
PSMD13	5948.0
NCOR1	5887.0
ST3GAL4	5781.0
PSMD8	5757.0
PSENEN	5735.0
AGO1	5654.0
YWHAZ	5624.0
HDAC2	5482.0
MAML1	5404.0
H2BC9	5394.0
PSMA2	5339.0
H2BC15	5312.0
NOTCH2	5272.0
SNW1	5201.0
PBX1	5098.0
H2AC20	4972.0
HDAC11	4756.0
HDAC5	4710.0
NOTCH1	4704.0
HDAC3	4673.0
PSMD3	4618.0
TBL1XR1	4556.0
UBC	4439.0
SEM1	4348.0
B4GALT1	4292.0
SKP1	4287.0
APH1A	4133.0
PSMB2	4084.0
RBX1	3934.0
JUN	3722.0
AKT1	3614.0
PSMD5	3426.0
CREBBP	3423.0
PSMB1	3374.0
DLGAP5	3106.0
YBX1	3097.0
HDAC8	3079.0
AGO2	2995.0
PSMD14	2611.0
PSMC2	2598.0
PSMB4	2523.0
MYC	2304.0
HDAC10	2280.0
POFUT1	2056.0
ARRB1	1998.0
PSMC3	1976.0
CCNC	1877.0
PSMD10	1559.0
HDAC9	1359.0
ITCH	1318.0
WWC1	1180.0
UBA52	1121.0
ELF3	828.0
HDAC1	587.0
ST3GAL3	505.0
PRKCI	-138.0
ACTA2	-429.0
MAML2	-582.0
PSMA4	-616.0
NBEA	-703.0
PSMC5	-863.0
ATP2A3	-914.0
AGO3	-1011.0
H2AZ2	-1209.0
CREB1	-1378.0
CDK8	-1971.0
KAT2B	-2414.0
NEURL1B	-2586.0
MIB1	-2998.0
PSMB8	-3076.0
DTX1	-3340.0
MDK	-3714.0
FCER2	-4230.0
TNRC6B	-4518.0
ATP2A1	-4667.0
NOTCH4	-5229.0
PSMA3	-5285.0
MAMLD1	-5584.0
TNRC6A	-5613.0
PSMB10	-5735.0
MFNG	-6008.0
PSMA5	-6053.0
H2BU1	-6555.0
FBXW7	-6600.0
RPS27A	-6938.0
TLE1	-6942.0
CCND1	-6970.0
FLT4	-7216.0
TLE2	-7449.0
IKZF1	-7704.0
PSEN2	-7718.0
HES1	-8266.0
HDAC6	-8337.0
LFNG	-8372.0
POGLUT1	-9094.0
PSMC4	-9127.0
HEY2	-9752.0
PSME1	-9991.0
PSME2	-10336.0
KAT2A	-10771.0
TP53	-10893.0
JAG2	-11044.0
MIB2	-11073.0
PSMB9	-11324.0
CUL1	-11330.0
NEURL1	-11633.0
STAT1	-11727.0
SMAD3	-11745.0
TNRC6C	-11828.0
DLL1	-11885.0
MOV10	-11991.0
GZMB	-12361.0
TFDP2	-12364.0

---

Interleukin-1 signaling

Interleukin-1 signaling

	555
set	Interleukin-1 signaling
setSize	98
pANOVA	5.37e-13
s.dist	0.422
p.adjustANOVA	2.45e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A12	9515
IL1RN	9381
NKIRAS2	9353
IL1R2	9188
APP	9177
IRAK3	9107
MAP2K1	9063
IL1R1	8917
MAP2K6	8887
TOLLIP	8572
PSMB7	8485
MAP3K3	8471
NOD2	8442
PSMD4	8402
PELI2	8314
PSME3	8251
MYD88	8136
PSMB5	8101
CHUK	7966
PSMD6	7846

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A12	9515
IL1RN	9381
NKIRAS2	9353
IL1R2	9188
APP	9177
IRAK3	9107
MAP2K1	9063
IL1R1	8917
MAP2K6	8887
TOLLIP	8572
PSMB7	8485
MAP3K3	8471
NOD2	8442
PSMD4	8402
PELI2	8314
PSME3	8251
MYD88	8136
PSMB5	8101
CHUK	7966
PSMD6	7846
PELI3	7716
PSMD9	7620
PSMD2	7411
PSMA1	7329
PSMD1	7241
PSMB3	7171
IL1RAP	7150
PSMA7	7096
PSMC1	7021
TAB2	6964
MAP2K4	6866
PSMB6	6813
NFKBIA	6807
PELI1	6715
PSMF1	6659
UBB	6639
PSMC6	6635
PSMD12	6556
NFKB1	6277
PSMD11	6231
FBXW11	6196
MAP3K8	6160
IRAK1	6131
PSMA6	5970
PSMD7	5963
PSMD13	5948
PSMD8	5757
TAB1	5681
UBE2V1	5637
TNIP2	5552
IKBKG	5377
PSMA2	5339
IL1B	4807
PSMD3	4618
UBC	4439
SEM1	4348
SKP1	4287
PSMB2	4084
SQSTM1	4081
RBX1	3934
PSMD5	3426
PSMB1	3374
TAB3	3160
PSMD14	2611
PSMC2	2598
PSMB4	2523
MAP3K7	2395
PSMC3	1976
UBE2N	1936
PSMD10	1559
AGER	1294
UBA52	1121
RIPK2	1025
NKIRAS1	375
NFKBIB	-152
TRAF6	-229
HMGB1	-252
PSMA4	-616
PSMC5	-863
NFKB2	-1165
RELA	-1803
PSMB8	-3076
BTRC	-4924
PSMA3	-5285
IKBKB	-5386
S100B	-5457
PSMB10	-5735
PSMA5	-6053
PSME4	-6087
RPS27A	-6938
PSMA8	-7606
PSMC4	-9127
IRAK2	-9548
PSME1	-9991
PSME2	-10336
PSMB9	-11324
CUL1	-11330
NOD1	-12263

---

Diseases of signal transduction by growth factor receptors and second messengers

Diseases of signal transduction by growth factor receptors and second messengers

	298
set	Diseases of signal transduction by growth factor receptors and second messengers
setSize	342
pANOVA	6.05e-13
s.dist	0.226
p.adjustANOVA	2.67e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FZD5	9513
GRB2	9304
NCSTN	9186
KREMEN1	9149
MAP2K1	9063
FKBP1A	9056
PIK3CB	9038
PAPSS1	9003
QKI	8996
CUX1	8986
KL	8963
HDAC4	8960
MAML3	8957
AGTRAP	8956
MAPK3	8953
ERLIN2	8928
OS9	8898
ITGA2B	8893
TGFA	8889
HGF	8863

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FZD5	9513
GRB2	9304
NCSTN	9186
KREMEN1	9149
MAP2K1	9063
FKBP1A	9056
PIK3CB	9038
PAPSS1	9003
QKI	8996
CUX1	8986
KL	8963
HDAC4	8960
MAML3	8957
AGTRAP	8956
MAPK3	8953
ERLIN2	8928
OS9	8898
ITGA2B	8893
TGFA	8889
HGF	8863
RAC1	8793
ADAM10	8791
RBPJ	8770
APBB1IP	8744
JAG1	8743
MARK3	8697
FOXO3	8682
IRS2	8569
TLN1	8525
ARRB2	8490
RHOG	8487
PSMB7	8485
PTEN	8460
PSMD4	8402
AP3B1	8365
BAG4	8328
ITGB3	8291
FN1	8284
PSME3	8251
PPP2CA	8234
EGF	8179
IQGAP1	8152
PTPN12	8151
ATG7	8134
ADAM17	8110
PSMB5	8101
GAB2	8099
STAT3	8098
NCOR2	7985
CHUK	7966
PSEN1	7961
VAV1	7896
TBL1X	7887
RAF1	7879
AKT1S1	7865
PSMD6	7846
FGFR1OP2	7834
PIK3AP1	7811
LYN	7809
CSNK1A1	7766
GSK3A	7760
PPP2CB	7712
CASP9	7685
MAP3K11	7626
PSMD9	7620
POLR2E	7563
MAPK1	7493
CBL	7480
PSMD2	7411
BCL2L11	7384
SHOC2	7333
PSMA1	7329
VCL	7328
RAP1A	7305
PSMD1	7241
PSMB3	7171
PSMA7	7096
PPP1CB	7064
PSMC1	7021
STAT5A	6965
SPRED2	6936
STAT5B	6925
BAD	6892
VCP	6886
KDM7A	6855
SEL1L	6847
PSMB6	6813
MAP2K2	6794
PPP2R5B	6774
POLR2J	6671
PSMF1	6659
VWF	6641
UBB	6639
PSMC6	6635
GSK3B	6634
PSMD12	6556
CTNNB1	6408
FOXO4	6391
YWHAB	6385
PPP1CC	6330
LRRFIP1	6302
APH1B	6280
PSMD11	6231
AGGF1	6191
PDPK1	6136
EP300	6129
HDAC7	6122
PIK3CD	6046
AREG	5977
PSMA6	5970
PSMD7	5963
PSMD13	5948
PPP2R5A	5897
NCOR1	5887
PDGFRA	5858
PSMD8	5757
BIN2	5745
PSENEN	5735
GAB1	5679
HDAC2	5482
ETV6	5443
GTF2F2	5434
MAML1	5404
BRAP	5387
NRAS	5363
PSMA2	5339
PTPN11	5314
FXR1	5308
POLR2L	5305
PDGFA	5293
CSK	5219
SNW1	5201
RAC2	5163
TGFB1	5153
MAPKAP1	5057
TRAK1	5022
HBEGF	5013
PIK3R2	5010
FAM114A2	4963
GTF2F1	4951
SMAD2	4905
HDAC11	4756
HDAC5	4710
NOTCH1	4704
HDAC3	4673
PIK3CA	4629
PSMD3	4618
POLR2F	4604
PPP2R1A	4589
TBL1XR1	4556
CDKN1A	4511
UBC	4439
DUSP6	4357
SEM1	4348
MDM2	4312
LRP5	4289
SKP1	4287
KSR1	4167
SHC1	4161
APH1A	4133
CDC37	4096
PSMB2	4084
CTBP2	4080
RBX1	3934
FGF2	3920
TGFBR2	3914
LMNA	3887
SND1	3849
TRIM24	3806
NRG1	3750
KRAS	3702
STRN	3695
KIAA1549	3618
AKT1	3614
POLR2G	3508
PSMD5	3426
CREBBP	3423
PSMB1	3374
ZMYM2	3368
APC	3240
RAP1B	3206
HDAC8	3079
DERL2	3041
NF1	3036
JAK2	2691
EPGN	2662
ARAF	2644
PSMD14	2611
PSMC2	2598
PSMB4	2523
PPP2R5D	2421
MYC	2304
HDAC10	2280
CLCN6	2232
ARRB1	1998
PSMC3	1976
CAMK2G	1921
EREG	1888
CCNC	1877
IRS1	1741
POLR2C	1616
TGFBR1	1585
PSMD10	1559
HDAC9	1359
HSP90AA1	1326
BRAF	1308
UBA52	1121
SYVN1	992
RPS6KB2	700
ERLEC1	698
HDAC1	587
LRP6	577
AKT2	433
POLR2I	396
MLST8	376
KREMEN2	316
CD86	-14
PPP2R1B	-241
ERBB3	-472
TNKS2	-499
ERBIN	-574
MAML2	-582
PSMA4	-616
PPP2R5E	-680
FAM131B	-734
TSC2	-804
PSMC5	-863
CREB1	-1378
DUSP10	-1650
POLR2K	-1783
NRG4	-1875
CDK8	-1971
CALM1	-2081
KAT2B	-2414
POLR2B	-2523
NEURL1B	-2586
POLR2H	-2942
PHB	-2995
MIB1	-2998
PSMB8	-3076
POLR2A	-3092
DUSP7	-3211
FGFR4	-3293
KSR2	-3361
HRAS	-3382
FRS2	-3433
CD19	-3843
KANK1	-3964
MYO18A	-3970
POLR2D	-4024
GOLGA4	-4064
FGF7	-4247
CNKSR2	-4781
AKAP9	-5020
PSMA3	-5285
FGFR1	-5352
MAMLD1	-5584
SOS1	-5700
PSMB10	-5735
NCBP1	-5853
PSMA5	-6053
PSME4	-6087
CPSF6	-6137
MRAS	-6172
TCF7L2	-6185
FOXO6	-6367
CTBP1	-6456
FZD6	-6525
FBXW7	-6600
FGF23	-6622
CNTRL	-6639
DUSP16	-6655
NR4A1	-6756
SPRED3	-6835
CD80	-6841
RPS27A	-6938
BCR	-7071
CNKSR1	-7089
FZD8	-7138
TRAT1	-7535
PSMA8	-7606
PSEN2	-7718
ZFYVE9	-7848
FIP1L1	-7928
CDKN1B	-8207
HES1	-8266
HDAC6	-8337
SMAD4	-8351
PDGFB	-8577
FGF22	-8607
SPRED1	-8639
TNKS	-8738
FGF9	-8761
SRC	-8820
ESR1	-9122
PSMC4	-9127
ESR2	-9250
HHAT	-9301
ICOS	-9434
FOXO1	-9465
PIK3R1	-9505
NCBP2	-9558
RICTOR	-9670
HEY2	-9752
MTOR	-9767
PSME1	-9991
ZC3HAV1	-10064
PORCN	-10074
CD28	-10202
AXIN1	-10285
PSME2	-10336
KAT2A	-10771
MPRIP	-10959
KIT	-11004
JAG2	-11044
MIB2	-11073
PLCG1	-11120
TENT4A	-11168
PPP2R5C	-11265
PEBP1	-11270
AMER1	-11301
PSMB9	-11324
CUL1	-11330
PDGFRB	-11545
WDR48	-11565
NEURL1	-11633
DUSP8	-11639
FZD4	-11650
FYN	-11675
STAT1	-11727
SMAD3	-11745
FGFR2	-11785
CAMK2D	-11816
LCK	-11838
AKT3	-11849
DLL1	-11885
PRR5	-11985
PIK3R3	-12015
AGK	-12120
RNF43	-12121
YES1	-12142
ERBB2	-12320

---

Major pathway of rRNA processing in the nucleolus and cytosol

Major pathway of rRNA processing in the nucleolus and cytosol

	627
set	Major pathway of rRNA processing in the nucleolus and cytosol
setSize	180
pANOVA	1.68e-12
s.dist	-0.305
p.adjustANOVA	7.18e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LAS1L	-12267
NOP56	-11750
RBM28	-11671
BMS1	-11670
PDCD11	-11518
UTP4	-11494
EXOSC8	-11456
EXOSC10	-11379
DDX47	-11299
EXOSC2	-11072
IMP4	-10976
WDR46	-10970
PELP1	-10928
NOL6	-10908
NOP14	-10866
EXOSC7	-10631
UTP15	-10603
UTP20	-10529
NOL11	-10471
HEATR1	-10345

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LAS1L	-12267
NOP56	-11750
RBM28	-11671
BMS1	-11670
PDCD11	-11518
UTP4	-11494
EXOSC8	-11456
EXOSC10	-11379
DDX47	-11299
EXOSC2	-11072
IMP4	-10976
WDR46	-10970
PELP1	-10928
NOL6	-10908
NOP14	-10866
EXOSC7	-10631
UTP15	-10603
UTP20	-10529
NOL11	-10471
HEATR1	-10345
NOB1	-10320
CSNK1E	-10298
EXOSC9	-10250
NOL9	-10224
EMG1	-10189
FBL	-10188
RRP9	-10080
NOP58	-9951
WDR75	-9921
EXOSC6	-9839
TEX10	-9765
RPS27	-9756
TSR1	-9731
RPL23A	-9567
IMP3	-9459
NCL	-9269
RPS20	-8886
RPL39L	-8805
KRR1	-8623
RPL3	-8561
GNL3	-8489
DHX37	-8267
RPP25	-8247
RPL13A	-8212
RPP30	-8101
RPL35	-8092
RPS29	-7940
MPHOSPH10	-7790
RPS18	-7744
WDR43	-7687
RPL36A	-7376
RPS11	-7243
RPLP2	-7087
RPP38	-7076
RPL12	-7053
RPL30	-7020
RPS19	-6965
RPS27A	-6938
SNU13	-6871
RPL41	-6866
PNO1	-6861
RPL34	-6802
RPL14	-6710
RPL32	-6709
RPL10A	-6686
WDR3	-6619
RPL26	-6612
RPL10	-6534
RPL21	-6458
RPL37	-6375
RPS25	-6365
RPSA	-6323
RPS23	-6292
RPS4X	-6285
RPL19	-6281
RPL11	-6261
RPL27A	-6257
RPS17	-6247
RPS6	-6160
RPL18A	-6070
RPL35A	-6015
RPS12	-5987
RPS3	-5914
NIP7	-5876
RPL38	-5840
RPL24	-5799
RPS10	-5793
RPS15A	-5742
RPS5	-5691
DCAF13	-5572
NOC4L	-5483
RPS14	-5463
RPL17	-5431
RPP21	-5355
RPL36	-5287
BOP1	-5212
RPL18	-5080
RPS7	-4968
RPP40	-4835
RPL22	-4740
RPL5	-4728
RPS28	-4713
RPS3A	-4694
RPS16	-4669
EXOSC5	-4577
RPL31	-4541
UTP6	-4507
RPS2	-4499
BYSL	-4461
DIS3	-4322
LTV1	-4296
EBNA1BP2	-4097
RPS21	-4079
FTSJ3	-4022
RPL37A	-3946
WDR36	-3945
RIOK1	-3814
RPS15	-3673
RPL7A	-3665
RPL29	-3611
RPL4	-3582
TBL3	-3437
RPL13	-3431
RPL6	-3354
RPL23	-3314
RRP1	-3084
RPL39	-3006
UTP3	-2903
RPL27	-2855
RRP7A	-2806
MTREX	-2638
SNORD3A	-2539
WDR18	-2310
RPS8	-2083
UTP14C	-2073
PES1	-2033
RPL7	-1955
RPL9	-1872
UTP14A	-1821
RPS13	-1749
RRP36	-1672
RPL22L1	-1619
RPL28	-1462
RPS26	-1430
PWP2	-1207
RPL8	-1187
RPLP0	-1000
EXOSC1	-991
RPL15	-963
RCL1	-757
FAU	-362
RPS24	-263
RPLP1	19
RPL36AL	32
RPS4Y1	424
DDX52	454
EXOSC3	509
RIOK2	934
UBA52	1121
RPS27L	2061
MPHOSPH6	2181
CSNK1D	2390
SENP3	2994
RPP14	3005
DDX21	3113
C1D	3516
ISG20L2	3775
FCF1	4472
RPL3L	4503
UTP11	4631
DDX49	4872
NOL12	4944
UTP18	5114
WDR12	5217
RPS9	5421
ERI1	5541
RPL26L1	7176
EXOSC4	7600
RIOK3	8765
XRN2	9400

---

Clathrin-mediated endocytosis

Clathrin-mediated endocytosis

	191
set	Clathrin-mediated endocytosis
setSize	127
pANOVA	3.15e-12
s.dist	0.358
p.adjustANOVA	1.3e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
VAMP7	9499
GRB2	9304
ITSN1	9289
AGFG1	9211
PICALM	9022
CLTC	9000
CLTCL1	8965
ARPC1A	8894
TGFA	8889
TGOLN2	8714
ARPC5	8686
RAB5C	8655
AP2M1	8627
FNBP1L	8551
AMPH	8532
ARRB2	8490
CLTA	8376
ARPC3	8277
HIP1	8258
VAMP3	8222

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
VAMP7	9499
GRB2	9304
ITSN1	9289
AGFG1	9211
PICALM	9022
CLTC	9000
CLTCL1	8965
ARPC1A	8894
TGFA	8889
TGOLN2	8714
ARPC5	8686
RAB5C	8655
AP2M1	8627
FNBP1L	8551
AMPH	8532
ARRB2	8490
CLTA	8376
ARPC3	8277
HIP1	8258
VAMP3	8222
EGF	8179
REPS2	8154
PACSIN2	8123
DAB2	8112
EPN1	8045
TOR1A	8033
AP2S1	8026
ACTR2	7870
ACTR3	7818
FCHO2	7807
SH3GL1	7625
ARPC4	7516
CBL	7480
ARPC2	7390
AP2A2	7257
IGF2R	7149
RAB5A	7103
DNM3	7045
SNX18	7017
AP2A1	6832
GAPVD1	6799
RAB5B	6690
UBB	6639
GRK3	6593
COPS7A	6590
NEDD8	6482
OCRL	6442
SYNJ1	6296
LDLR	6183
SH3KBP1	6173
STAM2	6159
COPS2	6139
DNM2	6089
CLTB	6084
GRK2	6068
COPS3	6005
AREG	5977
UBQLN2	5939
CTTN	5930
SCARB2	5255
VAMP8	5218
UBQLN1	5108
ITSN2	5060
SYT1	5056
HBEGF	5013
DNAJC6	4640
HGS	4513
UBC	4439
COPS5	4361
EPS15	4138
EPS15L1	3655
DNM1	3587
STON2	3569
PIP5K1C	3419
NECAP2	3387
VAMP4	3191
KIAA0319	3163
EPGN	2662
STON1	2574
GAK	2570
CFTR	2416
TRIP10	2343
NECAP1	2220
ARRB1	1998
EREG	1888
COPS4	1776
COPS6	1637
TFRC	1524
ARF6	1377
LRP2	1307
STAM	1285
UBA52	1121
TF	1102
SYT2	461
WASL	299
AVPR2	291
FNBP1	-311
SNX9	-430
ARFGAP1	-1942
TOR1B	-2136
FCHO1	-2392
AP2B1	-2709
EPN2	-4100
GPS1	-4517
PIK3C2A	-5194
CD4	-5406
SYT11	-6763
RPS27A	-6938
REPS1	-7137
SYNJ2	-8511
M6PR	-8519
COPS8	-8755
AAK1	-9190
LDLRAP1	-9326
COPS7B	-9775
IL7R	-10546
HIP1R	-10615
HSPA8	-10922
DVL2	-11152
CD3D	-11401
BIN1	-11411
CD3G	-11526
FZD4	-11650
SLC2A8	-11749
VAMP2	-11779
ADRB2	-11892
PACSIN1	-12374

---

Signaling by Rho GTPases

Signaling by Rho GTPases

	1135
set	Signaling by Rho GTPases
setSize	367
pANOVA	4.57e-12
s.dist	0.21
p.adjustANOVA	1.84e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
WASF1	9520
S100A9	9516
S100A8	9503
H2AJ	9374
RHOT1	9367
CTNNA1	9341
ARHGEF11	9305
GRB2	9304
ITSN1	9289
H2BC21	9283
NCF4	9268
CYFIP1	9265
YWHAG	9264
ARPC1B	9259
NCF2	9190
MAPK14	9104
H2BC12	9051
YWHAE	9045
CYBB	9031
ACTB	9011

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
WASF1	9520.0
S100A9	9516.0
S100A8	9503.0
H2AJ	9374.0
RHOT1	9367.0
CTNNA1	9341.0
ARHGEF11	9305.0
GRB2	9304.0
ITSN1	9289.0
H2BC21	9283.0
NCF4	9268.0
CYFIP1	9265.0
YWHAG	9264.0
ARPC1B	9259.0
NCF2	9190.0
MAPK14	9104.0
H2BC12	9051.0
YWHAE	9045.0
CYBB	9031.0
ACTB	9011.0
PRKCD	9008.0
DLG4	9007.0
MAPK3	8953.0
FGD4	8948.0
ARPC1A	8894.0
ARHGAP18	8852.0
RHOU	8794.0
RAC1	8793.0
ARHGEF40	8723.0
ARPC5	8686.0
H3-3A	8661.0
YWHAH	8649.0
ARHGDIB	8639.0
MYL6	8576.0
ACTG1	8562.0
WAS	8560.0
CLIP1	8540.0
DIAPH2	8523.0
DLC1	8488.0
RHOG	8487.0
WASF2	8369.0
ARHGAP26	8368.0
MRTFA	8350.0
RHOA	8319.0
SOS2	8299.0
ARPC3	8277.0
TAX1BP3	8262.0
KIF5B	8239.0
PPP2CA	8234.0
PAK1	8230.0
ARAP3	8225.0
CFL1	8186.0
PAK2	8185.0
B9D2	8168.0
IQGAP1	8152.0
ARHGAP29	8084.0
LIMK2	8074.0
H2BC5	8003.0
RHOBTB1	7943.0
H2AC6	7934.0
H2BC11	7912.0
VAV1	7896.0
ACTR2	7870.0
GMIP	7856.0
ACTR3	7818.0
ARAP1	7817.0
ARHGAP19	7756.0
DYNC1I2	7735.0
PPP2CB	7712.0
MYL9	7703.0
NCKAP1L	7673.0
MAPRE1	7658.0
NDEL1	7627.0
CDC42	7537.0
ARHGAP24	7523.0
ARPC4	7516.0
RHOQ	7511.0
MAPK1	7493.0
ROCK1	7489.0
NCKAP1	7462.0
ARHGAP6	7433.0
PLEKHG2	7395.0
FAM13A	7392.0
ARPC2	7390.0
H2BC4	7389.0
KLC3	7377.0
NCF1	7334.0
H2BC17	7285.0
GDI2	7282.0
BTK	7206.0
PRKCB	7097.0
ABI1	7082.0
SRF	7079.0
PPP1CB	7064.0
BRK1	7032.0
DYNC1LI1	6941.0
CYBA	6922.0
ARHGEF17	6852.0
PPP1R14A	6839.0
WASF3	6808.0
RALBP1	6796.0
PPP2R5B	6774.0
SRGAP1	6744.0
H3C15	6699.5
MYH9	6685.0
MYLK	6618.0
IQGAP2	6599.0
ARHGEF2	6546.0
OCRL	6442.0
MYO9B	6424.0
PREX1	6414.0
CTNNB1	6408.0
YWHAB	6385.0
PPP1CC	6330.0
ABR	6260.0
ARHGAP9	6256.0
SRGAP2	6171.0
ROCK2	6138.0
PDPK1	6136.0
ARHGDIA	6104.0
ARHGEF37	6100.0
PPP1R12A	6050.0
H2AZ1	6036.0
DYNLL1	5952.0
CTTN	5930.0
PPP2R5A	5897.0
GNA13	5836.0
ARHGAP27	5830.0
SEC13	5748.0
GDI1	5739.0
WIPF2	5713.0
DVL3	5656.0
YWHAZ	5624.0
ARHGAP23	5618.0
ECT2	5570.0
KLC1	5523.0
ARHGAP31	5501.0
PAFAH1B1	5470.0
PFN1	5459.0
TAOK1	5420.0
NSL1	5408.0
H2BC9	5394.0
H2BC15	5312.0
RAC2	5163.0
MYL12B	5088.0
ARHGAP30	5039.0
ARHGAP21	5032.0
PIK3R2	5010.0
H2AC20	4972.0
CDC25C	4969.0
CHN2	4938.0
VAV3	4894.0
AR	4840.0
LIMK1	4679.0
ARHGAP1	4613.0
PPP2R1A	4589.0
FGD2	4576.0
PTK2	4462.0
DIAPH3	4379.0
DYNC1LI2	4273.0
DYNC1I1	4187.0
CENPA	4162.0
FMNL1	4150.0
CDC20	3998.0
STARD8	3913.0
MAPK11	3826.0
BIRC5	3738.0
DAAM1	3466.0
FGD3	3408.0
AKAP13	3393.0
IQGAP3	3370.0
PMF1	3364.0
KTN1	3363.0
BUB1	3362.0
KIF14	3352.0
ARHGEF12	3166.0
NUP98	3101.0
STARD13	3078.0
NUP37	3074.0
KLK2	3029.0
PLK1	3002.0
BUB1B	2997.0
RACGAP1	2848.0
ARHGAP28	2835.0
CENPF	2723.0
SKA1	2649.0
ARHGAP32	2642.0
NDE1	2594.0
ARHGEF6	2453.0
PPP2R5D	2421.0
CFTR	2416.0
TRIP10	2343.0
SPC24	2306.0
MCF2	2018.0
TRIO	1820.0
PPP1R12B	1775.0
DEPDC1B	1774.0
ARHGAP11A	1642.0
PIK3C3	1619.0
SFN	1615.0
ARHGAP22	1595.0
RHOB	1254.0
ARHGAP4	1204.0
PRKCA	1132.0
NCOA2	1092.0
PRC1	980.0
AURKB	846.0
KIF2C	726.0
DEPDC7	725.0
MYH10	653.0
TIAM1	651.0
WIPF1	569.0
FLNA	483.0
CENPE	332.0
NCKIPSD	328.0
WASL	299.0
ARHGAP15	272.0
ABL1	226.0
PKN2	98.0
ZW10	31.0
CENPN	20.0
DVL1	0.0
ITGB1	-94.0
BAIAP2	-215.0
PPP2R1B	-241.0
ERCC6L	-415.0
ARHGAP44	-483.0
KNL1	-581.0
CLASP1	-588.0
PPP2R5E	-680.0
NUDC	-709.0
RANBP2	-820.0
SYDE2	-845.0
DIAPH1	-854.0
KIF2A	-1069.0
OPHN1	-1158.0
XPO1	-1185.0
H2AZ2	-1209.0
AHCTF1	-1644.0
CDCA8	-1838.0
CALM1	-2081.0
CLASP2	-2151.0
PKN1	-2208.0
PFN2	-2339.0
KIF18A	-2742.0
NUP85	-3049.0
CENPI	-3162.0
PIN1	-3188.0
RAC3	-3262.0
ARHGAP35	-3359.0
SGO2	-3480.0
MYH11	-3522.0
KALRN	-3692.0
LIN7B	-3725.0
PKN3	-3793.0
ARHGEF4	-3861.0
ARHGEF38	-3906.0
ARHGEF26	-3971.0
DYNLL2	-3980.0
ARHGEF10	-4015.0
VAV2	-4055.0
PIK3R4	-4062.0
PAK3	-4184.0
NUF2	-4301.0
FMNL2	-4424.0
ARHGEF35	-4533.0
ARHGEF7	-4583.0
RHPN2	-4650.0
ZWINT	-4742.0
MAD1L1	-4981.0
CIT	-5064.0
CENPO	-5135.0
RCC2	-5148.0
RHPN1	-5327.0
CENPM	-5376.0
NOXA1	-5464.0
ARHGAP33	-5517.0
RHOT2	-5546.0
RHOBTB2	-5551.0
ARHGEF1	-5559.0
SRGAP3	-5675.0
SOS1	-5700.0
INCENP	-5956.0
SEH1L	-6069.0
CKAP5	-6246.0
ARHGEF10L	-6295.0
CENPQ	-6366.0
NF2	-6540.0
H2BU1	-6555.0
CENPU	-6692.0
SGO1	-6715.0
OBSCN	-6727.0
ARHGEF18	-6799.0
ARHGEF5	-6944.0
INPP5B	-7024.0
BCR	-7071.0
YWHAQ	-7340.0
NET1	-7419.0
ARHGAP12	-7547.0
ARHGAP42	-7608.0
ITGB3BP	-7621.0
DYNC1H1	-7685.0
NUP133	-7762.0
ARHGAP11B	-7789.0
CHN1	-7833.0
SCAI	-7879.0
ARHGAP17	-7888.0
KNTC1	-7897.0
MAD2L1	-7944.0
ARHGAP39	-8166.0
CDKN1B	-8207.0
CENPK	-8334.0
KLC4	-8376.0
ARHGAP25	-8441.0
MEN1	-8538.0
MCF2L	-8571.0
CENPH	-8633.0
PLEKHG5	-8758.0
ARHGEF19	-8776.0
SRC	-8820.0
ARHGAP10	-8847.0
KIF5A	-8869.0
ARHGAP5	-8885.0
SKA2	-8999.0
KLC2	-9059.0
NDC80	-9165.0
KDM1A	-9430.0
NUP43	-9517.0
MYO9A	-9588.0
CENPT	-9606.0
RPS27	-9756.0
GOPC	-9831.0
A2M	-9870.0
RASGRF2	-10175.0
CYFIP2	-10367.0
NUP107	-10421.0
FAM13B	-10519.0
NUP160	-10557.0
RHOH	-10626.0
KDM4C	-10749.0
DSN1	-10773.0
ARHGEF39	-10833.0
MIS12	-10903.0
ABI2	-10915.0
TIAM2	-10979.0
DVL2	-11152.0
PPP2R5C	-11265.0
RHOC	-11360.0
NCK1	-11454.0
CDH1	-11500.0
SPDL1	-11534.0
PRKCZ	-11629.0
BUB3	-11709.0
RANGAP1	-11722.0
ZWILCH	-11724.0
CENPL	-11782.0
CENPP	-11814.0
CENPC	-11888.0
ARAP2	-11984.0
ARHGEF3	-12022.0
FMNL3	-12087.0
EVL	-12207.0
RTKN	-12249.0
ARHGAP8	-12284.0
TAGAP	-12285.0
ARHGEF9	-12299.0
RHOF	-12344.0

---

Interleukin-1 family signaling

Interleukin-1 family signaling

	554
set	Interleukin-1 family signaling
setSize	125
pANOVA	8.55e-12
s.dist	0.353
p.adjustANOVA	3.34e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A12	9515
IL1RN	9381
NKIRAS2	9353
IL1R2	9188
APP	9177
IRAK3	9107
MAP2K1	9063
ALOX5	9001
IL1R1	8917
MAP2K6	8887
TOLLIP	8572
PSMB7	8485
MAP3K3	8471
NOD2	8442
PSMD4	8402
PELI2	8314
PSME3	8251
PTPN12	8151
MYD88	8136
PSMB5	8101

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A12	9515
IL1RN	9381
NKIRAS2	9353
IL1R2	9188
APP	9177
IRAK3	9107
MAP2K1	9063
ALOX5	9001
IL1R1	8917
MAP2K6	8887
TOLLIP	8572
PSMB7	8485
MAP3K3	8471
NOD2	8442
PSMD4	8402
PELI2	8314
PSME3	8251
PTPN12	8151
MYD88	8136
PSMB5	8101
STAT3	8098
CHUK	7966
PSMD6	7846
PELI3	7716
PSMD9	7620
PTPN2	7615
PSMD2	7411
IL18	7381
PSMA1	7329
PSMD1	7241
PSMB3	7171
IL1RAP	7150
PSMA7	7096
PSMC1	7021
TAB2	6964
MAP2K4	6866
PSMB6	6813
NFKBIA	6807
PELI1	6715
PTPN9	6712
PSMF1	6659
UBB	6639
PSMC6	6635
PSMD12	6556
NFKB1	6277
PSMD11	6231
FBXW11	6196
MAP3K8	6160
PTPN18	6149
IRAK1	6131
PTPN6	6096
PSMA6	5970
PSMD7	5963
PSMD13	5948
PSMD8	5757
TAB1	5681
UBE2V1	5637
TNIP2	5552
IKBKG	5377
PSMA2	5339
PTPN11	5314
CTSG	5115
IL1B	4807
PSMD3	4618
UBC	4439
SEM1	4348
SKP1	4287
CASP1	4224
PSMB2	4084
SQSTM1	4081
IL18R1	3994
RBX1	3934
PSMD5	3426
PSMB1	3374
TBK1	3229
IL1RL1	3175
TAB3	3160
PSMD14	2611
PSMC2	2598
PSMB4	2523
MAP3K7	2395
PSMC3	1976
UBE2N	1936
PSMD10	1559
AGER	1294
UBA52	1121
RIPK2	1025
IL18RAP	823
IL33	445
NKIRAS1	375
NFKBIB	-152
TRAF6	-229
HMGB1	-252
PSMA4	-616
PSMC5	-863
NFKB2	-1165
PTPN23	-1186
RELA	-1803
PTPN14	-2386
PSMB8	-3076
PTPN20	-3783
BTRC	-4924
PSMA3	-5285
IKBKB	-5386
S100B	-5457
PSMB10	-5735
PSMA5	-6053
PSME4	-6087
RPS27A	-6938
PSMA8	-7606
PSMC4	-9127
MAPK8	-9428
IRAK2	-9548
PTPN13	-9962
PSME1	-9991
PSME2	-10336
IL4	-10399
IL18BP	-10561
SIGIRR	-10752
PTPN7	-10868
PSMB9	-11324
CUL1	-11330
SMAD3	-11745
PTPN4	-12220
NOD1	-12263

---

Signaling by NTRKs

Signaling by NTRKs

	1122
set	Signaling by NTRKs
setSize	116
pANOVA	9.74e-12
s.dist	0.366
p.adjustANOVA	3.69e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GRB2	9304
DUSP3	9280
RIT1	9121
MAPK14	9104
FURIN	9075
MAP2K1	9063
PIK3CB	9038
CLTC	9000
MAPK3	8953
CRK	8906
RAC1	8793
FOSL1	8788
PCSK6	8740
AP2M1	8627
CDK5	8616
IRS2	8569
RALB	8414
MAPKAPK3	8382
CLTA	8376
RHOA	8319

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GRB2	9304
DUSP3	9280
RIT1	9121
MAPK14	9104
FURIN	9075
MAP2K1	9063
PIK3CB	9038
CLTC	9000
MAPK3	8953
CRK	8906
RAC1	8793
FOSL1	8788
PCSK6	8740
AP2M1	8627
CDK5	8616
IRS2	8569
RALB	8414
MAPKAPK3	8382
CLTA	8376
RHOA	8319
PPP2CA	8234
LYL1	8221
STAT3	8098
AP2S1	8026
MEF2A	8009
PPP2CB	7712
RPS6KA1	7695
TRIB1	7643
MAPK1	7493
FRS3	7343
RAP1A	7305
AP2A2	7257
SRF	7079
KIDINS220	7069
DNM3	7045
AP2A1	6832
JUNB	6806
MAP2K2	6794
YWHAB	6385
EP300	6129
DNM2	6089
BAX	5916
ATF1	5706
GAB1	5679
FOS	5460
NRAS	5363
PTPN11	5314
PIK3R2	5010
ID1	4927
PCSK5	4863
PIK3CA	4629
SGK1	4595
PPP2R1A	4589
DUSP6	4357
SHC2	4183
SHC1	4161
MAPKAPK2	4054
SHC3	3974
CRKL	3966
MAP2K5	3940
MAPK13	3865
MAPK11	3826
KRAS	3702
DNM1	3587
DNAL4	3398
ADORA2A	3293
EGR1	3124
RPS6KA2	3087
NTRK3	3068
RPS6KA3	2973
RALA	2710
PTPRO	2501
PPP2R5D	2421
ATF2	2085
IRS1	1741
JUND	1549
FOSB	1368
NAB1	1342
BRAF	1308
VRK3	1281
TF	1102
ELK1	1040
REST	865
TIAM1	651
NELFB	374
EGR3	44
PPP2R1B	-241
MEF2C	-293
MAPK12	-1074
CDK5R1	-1089
TCF12	-1233
MAPK7	-1337
CREB1	-1378
EGR2	-1435
AP2B1	-2709
MEF2D	-3094
DUSP7	-3211
HRAS	-3382
FRS2	-3433
CHD4	-4515
DOCK3	-4640
SOS1	-5700
DUSP4	-6287
NTRK1	-8193
TPH1	-8640
SRC	-8820
PIK3R1	-9505
ID3	-9614
RAPGEF1	-9826
NAB2	-10400
ID2	-10969
PLCG1	-11120
RPS6KA5	-11594
FYN	-11675
RALGDS	-12140
PTPRS	-12291

---

Transport to the Golgi and subsequent modification

Transport to the Golgi and subsequent modification

	1294
set	Transport to the Golgi and subsequent modification
setSize	155
pANOVA	1.6e-11
s.dist	0.313
p.adjustANOVA	5.89e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
F5	9485
ARF4	9191
SERPINA1	9168
DCTN2	9157
SPTB	9154
CD55	9145
KDELR1	9142
ARF1	9064
RAB1A	9052
CTSZ	8975
TGFA	8889
B4GALT5	8830
NSF	8829
ANK1	8771
MGAT4B	8675
CAPZA2	8597
DCTN4	8387
COPA	8366
RAB1B	8313
CAPZA1	8135

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
F5	9485
ARF4	9191
SERPINA1	9168
DCTN2	9157
SPTB	9154
CD55	9145
KDELR1	9142
ARF1	9064
RAB1A	9052
CTSZ	8975
TGFA	8889
B4GALT5	8830
NSF	8829
ANK1	8771
MGAT4B	8675
CAPZA2	8597
DCTN4	8387
COPA	8366
RAB1B	8313
CAPZA1	8135
SEC24D	8115
CAPZB	8015
TMED7	7950
MAN1A1	7927
COPB2	7902
ARF5	7885
TRAPPC1	7806
CNIH1	7779
DYNC1I2	7735
ARF3	7732
KDELR2	7728
SEC24A	7660
ACTR10	7605
SPTA1	7595
COPG2	7594
COPG1	7509
FUCA1	7408
SEC23A	7335
COPB1	7321
DCTN6	7300
TMED9	7167
STX5	7166
TFG	7160
TRAPPC3	7114
MCFD2	7099
LMAN2	7080
F8	7022
ACTR1A	7002
DYNC1LI1	6941
LMAN2L	6937
COPE	6896
PPP6C	6819
MAN2A2	6625
GORASP1	6606
SAR1B	6479
PREB	6368
COL7A1	6304
MGAT1	6257
GOLGA2	6203
TMED2	6052
DCTN3	5994
AREG	5977
DYNLL1	5952
CHST8	5900
SEC22B	5873
CD59	5859
ST3GAL4	5781
SEC13	5748
ARCN1	5580
MIA2	5574
TMEM115	5508
TRAPPC9	5333
PPP6R1	5263
YKT6	5205
TRAPPC5	5191
DCTN1	5078
SEC16A	4619
B4GALT1	4292
DYNC1LI2	4273
COG7	4269
DYNC1I1	4187
USO1	4154
TRAPPC6B	4147
NAPG	4139
COPZ1	4035
ARFGAP3	3714
SEC24B	3608
SCFD1	3525
PPP6R3	3261
TMED3	2720
CSNK1D	2390
CTSC	2326
MGAT2	1633
NAPA	1432
SEC31A	1099
CNIH2	654
B4GALT4	391
SEC16B	330
TMED10	323
COG4	-6
TBC1D20	-18
GOSR1	-182
COG8	-346
SEC23IP	-468
BET1	-594
MANEA	-699
MAN2A1	-1349
GOSR2	-1456
ARFGAP1	-1942
MAN1A2	-2055
MGAT4C	-2109
KDELR3	-2117
TRAPPC2L	-2299
MGAT3	-2391
SEC24C	-2569
NAPB	-2780
MGAT5	-3072
COG5	-3259
SPTBN5	-3531
DYNLL2	-3980
DCTN5	-4086
SEC22C	-4248
GBF1	-4290
ANK3	-4919
SEC22A	-5052
SPTBN2	-5129
GOLGB1	-5370
COG3	-5426
MGAT4A	-5680
ARFGAP2	-5786
COG6	-5811
B4GALT2	-6034
MIA3	-6245
ANKRD28	-6250
TRAPPC4	-6712
MAN1C1	-6804
BET1L	-7405
DYNC1H1	-7685
SPTBN1	-7764
COG2	-7917
TRAPPC2	-8704
B4GALT6	-8785
CNIH3	-9011
TRAPPC10	-9369
FUT8	-9755
LMAN1	-10630
B4GALT3	-10759
COPZ2	-10863
TRAPPC6A	-10917
STX17	-11006
SPTAN1	-11426
ST8SIA6	-11516
CHST10	-11841
ST6GAL1	-12052
COG1	-12125

---

Antigen processing-Cross presentation

Antigen processing-Cross presentation

	75
set	Antigen processing-Cross presentation
setSize	98
pANOVA	1.88e-11
s.dist	0.392
p.adjustANOVA	6.76e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CD36	9444
FCGR1A	9323
NCF4	9268
NCF2	9190
TLR2	9103
CD14	9097
FCGR1B	9053
CYBB	9031
TLR4	9016
TLR1	8932
TLR6	8840
LY96	8795
SNAP23	8628
PSMB7	8485
PSMD4	8402
CTSS	8372
PSME3	8251
VAMP3	8222
MYD88	8136
PSMB5	8101

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CD36	9444
FCGR1A	9323
NCF4	9268
NCF2	9190
TLR2	9103
CD14	9097
FCGR1B	9053
CYBB	9031
TLR4	9016
TLR1	8932
TLR6	8840
LY96	8795
SNAP23	8628
PSMB7	8485
PSMD4	8402
CTSS	8372
PSME3	8251
VAMP3	8222
MYD88	8136
PSMB5	8101
CHUK	7966
PSMD6	7846
PSMD9	7620
PSMD2	7411
NCF1	7334
PSMA1	7329
PSMD1	7241
BTK	7206
PSMB3	7171
PSMA7	7096
PSMC1	7021
SEC61B	7013
ITGB5	6923
CYBA	6922
PSMB6	6813
PSMF1	6659
UBB	6639
PSMC6	6635
PSMD12	6556
SEC61A1	6449
CALR	6340
PSMD11	6231
ITGAV	6106
PSMA6	5970
PSMD7	5963
PSMD13	5948
SEC22B	5873
PSMD8	5757
TIRAP	5640
IKBKG	5377
PSMA2	5339
VAMP8	5218
SEC61G	4708
PSMD3	4618
UBC	4439
SEM1	4348
CTSL	4231
PDIA3	4128
PSMB2	4084
PSMD5	3426
PSMB1	3374
MRC1	3109
TAPBP	3010
PSMD14	2611
PSMC2	2598
PSMB4	2523
PSMC3	1976
PSMD10	1559
UBA52	1121
HLA-C	1018
HLA-B	649
STX4	606
MRC2	-165
PSMA4	-616
PSMC5	-863
HLA-G	-2457
HLA-A	-2573
CTSV	-3036
PSMB8	-3076
HLA-H	-3889
HLA-E	-4415
PSMA3	-5285
IKBKB	-5386
PSMB10	-5735
PSMA5	-6053
PSME4	-6087
B2M	-6920
RPS27A	-6938
PSMA8	-7606
PSMC4	-9127
LNPEP	-9618
PSME1	-9991
PSME2	-10336
TAP1	-10787
SEC61A2	-10798
HLA-F	-11138
PSMB9	-11324
TAP2	-11807

---

RHO GTPase Effectors

RHO GTPase Effectors

	886
set	RHO GTPase Effectors
setSize	250
pANOVA	2.78e-11
s.dist	0.244
p.adjustANOVA	9.74e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
WASF1	9520
S100A9	9516
S100A8	9503
H2AJ	9374
CTNNA1	9341
GRB2	9304
H2BC21	9283
NCF4	9268
CYFIP1	9265
YWHAG	9264
ARPC1B	9259
NCF2	9190
MAPK14	9104
H2BC12	9051
YWHAE	9045
CYBB	9031
ACTB	9011
PRKCD	9008
DLG4	9007
MAPK3	8953

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
WASF1	9520.0
S100A9	9516.0
S100A8	9503.0
H2AJ	9374.0
CTNNA1	9341.0
GRB2	9304.0
H2BC21	9283.0
NCF4	9268.0
CYFIP1	9265.0
YWHAG	9264.0
ARPC1B	9259.0
NCF2	9190.0
MAPK14	9104.0
H2BC12	9051.0
YWHAE	9045.0
CYBB	9031.0
ACTB	9011.0
PRKCD	9008.0
DLG4	9007.0
MAPK3	8953.0
ARPC1A	8894.0
RAC1	8793.0
ARPC5	8686.0
H3-3A	8661.0
YWHAH	8649.0
MYL6	8576.0
ACTG1	8562.0
WAS	8560.0
CLIP1	8540.0
DIAPH2	8523.0
RHOG	8487.0
WASF2	8369.0
MRTFA	8350.0
RHOA	8319.0
ARPC3	8277.0
TAX1BP3	8262.0
KIF5B	8239.0
PPP2CA	8234.0
PAK1	8230.0
CFL1	8186.0
PAK2	8185.0
B9D2	8168.0
IQGAP1	8152.0
LIMK2	8074.0
H2BC5	8003.0
H2AC6	7934.0
H2BC11	7912.0
ACTR2	7870.0
ACTR3	7818.0
DYNC1I2	7735.0
PPP2CB	7712.0
MYL9	7703.0
NCKAP1L	7673.0
MAPRE1	7658.0
NDEL1	7627.0
CDC42	7537.0
ARPC4	7516.0
RHOQ	7511.0
MAPK1	7493.0
ROCK1	7489.0
NCKAP1	7462.0
ARPC2	7390.0
H2BC4	7389.0
KLC3	7377.0
NCF1	7334.0
H2BC17	7285.0
BTK	7206.0
PRKCB	7097.0
ABI1	7082.0
SRF	7079.0
PPP1CB	7064.0
BRK1	7032.0
DYNC1LI1	6941.0
CYBA	6922.0
PPP1R14A	6839.0
WASF3	6808.0
PPP2R5B	6774.0
H3C15	6699.5
MYH9	6685.0
MYLK	6618.0
IQGAP2	6599.0
CTNNB1	6408.0
YWHAB	6385.0
PPP1CC	6330.0
SRGAP2	6171.0
ROCK2	6138.0
PDPK1	6136.0
PPP1R12A	6050.0
H2AZ1	6036.0
DYNLL1	5952.0
CTTN	5930.0
PPP2R5A	5897.0
SEC13	5748.0
WIPF2	5713.0
DVL3	5656.0
YWHAZ	5624.0
KLC1	5523.0
PAFAH1B1	5470.0
PFN1	5459.0
TAOK1	5420.0
NSL1	5408.0
H2BC9	5394.0
H2BC15	5312.0
RAC2	5163.0
MYL12B	5088.0
H2AC20	4972.0
CDC25C	4969.0
AR	4840.0
LIMK1	4679.0
PPP2R1A	4589.0
PTK2	4462.0
DIAPH3	4379.0
DYNC1LI2	4273.0
DYNC1I1	4187.0
CENPA	4162.0
FMNL1	4150.0
CDC20	3998.0
MAPK11	3826.0
BIRC5	3738.0
DAAM1	3466.0
IQGAP3	3370.0
PMF1	3364.0
KTN1	3363.0
BUB1	3362.0
KIF14	3352.0
NUP98	3101.0
NUP37	3074.0
KLK2	3029.0
PLK1	3002.0
BUB1B	2997.0
CENPF	2723.0
SKA1	2649.0
NDE1	2594.0
PPP2R5D	2421.0
CFTR	2416.0
SPC24	2306.0
PPP1R12B	1775.0
PIK3C3	1619.0
SFN	1615.0
RHOB	1254.0
PRKCA	1132.0
NCOA2	1092.0
PRC1	980.0
AURKB	846.0
KIF2C	726.0
MYH10	653.0
WIPF1	569.0
FLNA	483.0
CENPE	332.0
NCKIPSD	328.0
WASL	299.0
ABL1	226.0
PKN2	98.0
ZW10	31.0
CENPN	20.0
DVL1	0.0
ITGB1	-94.0
BAIAP2	-215.0
PPP2R1B	-241.0
ERCC6L	-415.0
KNL1	-581.0
CLASP1	-588.0
PPP2R5E	-680.0
NUDC	-709.0
RANBP2	-820.0
DIAPH1	-854.0
KIF2A	-1069.0
XPO1	-1185.0
H2AZ2	-1209.0
AHCTF1	-1644.0
CDCA8	-1838.0
CALM1	-2081.0
CLASP2	-2151.0
PKN1	-2208.0
PFN2	-2339.0
KIF18A	-2742.0
NUP85	-3049.0
CENPI	-3162.0
PIN1	-3188.0
SGO2	-3480.0
MYH11	-3522.0
LIN7B	-3725.0
PKN3	-3793.0
DYNLL2	-3980.0
PIK3R4	-4062.0
PAK3	-4184.0
NUF2	-4301.0
FMNL2	-4424.0
RHPN2	-4650.0
ZWINT	-4742.0
MAD1L1	-4981.0
CIT	-5064.0
CENPO	-5135.0
RCC2	-5148.0
RHPN1	-5327.0
CENPM	-5376.0
NOXA1	-5464.0
INCENP	-5956.0
SEH1L	-6069.0
CKAP5	-6246.0
CENPQ	-6366.0
NF2	-6540.0
H2BU1	-6555.0
CENPU	-6692.0
SGO1	-6715.0
YWHAQ	-7340.0
ITGB3BP	-7621.0
DYNC1H1	-7685.0
NUP133	-7762.0
SCAI	-7879.0
KNTC1	-7897.0
MAD2L1	-7944.0
CDKN1B	-8207.0
CENPK	-8334.0
KLC4	-8376.0
MEN1	-8538.0
CENPH	-8633.0
SRC	-8820.0
KIF5A	-8869.0
SKA2	-8999.0
KLC2	-9059.0
NDC80	-9165.0
KDM1A	-9430.0
NUP43	-9517.0
CENPT	-9606.0
RPS27	-9756.0
GOPC	-9831.0
CYFIP2	-10367.0
NUP107	-10421.0
NUP160	-10557.0
KDM4C	-10749.0
DSN1	-10773.0
MIS12	-10903.0
ABI2	-10915.0
DVL2	-11152.0
PPP2R5C	-11265.0
RHOC	-11360.0
NCK1	-11454.0
CDH1	-11500.0
SPDL1	-11534.0
PRKCZ	-11629.0
BUB3	-11709.0
RANGAP1	-11722.0
ZWILCH	-11724.0
CENPL	-11782.0
CENPP	-11814.0
CENPC	-11888.0
FMNL3	-12087.0
EVL	-12207.0
RTKN	-12249.0

---

TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation

TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation

	1215
set	TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
setSize	87
pANOVA	3.99e-11
s.dist	0.409
p.adjustANOVA	1.36e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
DUSP3	9280
APP	9177
MAPK14	9104
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
MAP2K6	8887
LY96	8795
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966
PELI3	7716

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
DUSP3	9280
APP	9177
MAPK14	9104
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
MAP2K6	8887
LY96	8795
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966
PELI3	7716
PPP2CB	7712
RPS6KA1	7695
MAPK1	7493
TAB2	6964
MAP2K4	6866
NFKBIA	6807
PELI1	6715
UBB	6639
TICAM2	6335
TICAM1	6307
NFKB1	6277
FBXW11	6196
MAP3K8	6160
IRAK1	6131
ATF1	5706
TAB1	5681
UBE2V1	5637
TNIP2	5552
FOS	5460
IKBKG	5377
MAP3K1	5121
ECSIT	4918
PPP2R1A	4589
UBC	4439
DUSP6	4357
MAPK10	4325
SKP1	4287
MAPKAPK2	4054
MAPK11	3826
JUN	3722
TAB3	3160
RPS6KA2	3087
RPS6KA3	2973
PPP2R5D	2421
MAP3K7	2395
ATF2	2085
UBE2N	1936
MAP2K7	1654
AGER	1294
VRK3	1281
UBA52	1121
ELK1	1040
RIPK2	1025
NKIRAS1	375
NFKBIB	-152
TRAF6	-229
PPP2R1B	-241
HMGB1	-252
MEF2C	-293
TLR7	-625
NFKB2	-1165
MAPK7	-1337
CREB1	-1378
RELA	-1803
DUSP7	-3211
BTRC	-4924
IKBKB	-5386
S100B	-5457
TLR9	-5999
DUSP4	-6287
RPS27A	-6938
MAPK9	-7068
MAPK8	-9428
IRAK2	-9548
CUL1	-11330
RPS6KA5	-11594
NOD1	-12263

---

Toll Like Receptor 7/8 (TLR7/8) Cascade

Toll Like Receptor 7/8 (TLR7/8) Cascade

	1243
set	Toll Like Receptor 7/8 (TLR7/8) Cascade
setSize	89
pANOVA	4.41e-11
s.dist	0.404
p.adjustANOVA	1.47e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
TLR8	9343
DUSP3	9280
APP	9177
MAPK14	9104
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
MAP2K6	8887
LY96	8795
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
TLR8	9343
DUSP3	9280
APP	9177
MAPK14	9104
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
MAP2K6	8887
LY96	8795
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966
PELI3	7716
PPP2CB	7712
RPS6KA1	7695
MAPK1	7493
TAB2	6964
MAP2K4	6866
NFKBIA	6807
PELI1	6715
UBB	6639
TICAM2	6335
TICAM1	6307
NFKB1	6277
FBXW11	6196
MAP3K8	6160
IRAK1	6131
ATF1	5706
TAB1	5681
UBE2V1	5637
TNIP2	5552
FOS	5460
IKBKG	5377
MAP3K1	5121
ECSIT	4918
PPP2R1A	4589
UBC	4439
DUSP6	4357
MAPK10	4325
SKP1	4287
MAPKAPK2	4054
MAPK11	3826
JUN	3722
TAB3	3160
RPS6KA2	3087
RPS6KA3	2973
PPP2R5D	2421
MAP3K7	2395
ATF2	2085
UBE2N	1936
MAP2K7	1654
AGER	1294
VRK3	1281
UBA52	1121
ELK1	1040
RIPK2	1025
NKIRAS1	375
NFKBIB	-152
TRAF6	-229
PPP2R1B	-241
HMGB1	-252
MEF2C	-293
TLR7	-625
NFKB2	-1165
MAPK7	-1337
CREB1	-1378
RELA	-1803
DUSP7	-3211
BTRC	-4924
IKBKB	-5386
S100B	-5457
TLR9	-5999
DUSP4	-6287
RPS27A	-6938
MAPK9	-7068
IRF7	-8657
MAPK8	-9428
IRAK2	-9548
CUL1	-11330
RPS6KA5	-11594
NOD1	-12263

---

MyD88 dependent cascade initiated on endosome

MyD88 dependent cascade initiated on endosome

	688
set	MyD88 dependent cascade initiated on endosome
setSize	88
pANOVA	1.16e-10
s.dist	0.397
p.adjustANOVA	3.77e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
DUSP3	9280
APP	9177
MAPK14	9104
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
MAP2K6	8887
LY96	8795
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966
PELI3	7716

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
DUSP3	9280
APP	9177
MAPK14	9104
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
MAP2K6	8887
LY96	8795
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966
PELI3	7716
PPP2CB	7712
RPS6KA1	7695
MAPK1	7493
TAB2	6964
MAP2K4	6866
NFKBIA	6807
PELI1	6715
UBB	6639
TICAM2	6335
TICAM1	6307
NFKB1	6277
FBXW11	6196
MAP3K8	6160
IRAK1	6131
ATF1	5706
TAB1	5681
UBE2V1	5637
TNIP2	5552
FOS	5460
IKBKG	5377
MAP3K1	5121
ECSIT	4918
PPP2R1A	4589
UBC	4439
DUSP6	4357
MAPK10	4325
SKP1	4287
MAPKAPK2	4054
MAPK11	3826
JUN	3722
TAB3	3160
RPS6KA2	3087
RPS6KA3	2973
PPP2R5D	2421
MAP3K7	2395
ATF2	2085
UBE2N	1936
MAP2K7	1654
AGER	1294
VRK3	1281
UBA52	1121
ELK1	1040
RIPK2	1025
NKIRAS1	375
NFKBIB	-152
TRAF6	-229
PPP2R1B	-241
HMGB1	-252
MEF2C	-293
TLR7	-625
NFKB2	-1165
MAPK7	-1337
CREB1	-1378
RELA	-1803
DUSP7	-3211
BTRC	-4924
IKBKB	-5386
S100B	-5457
TLR9	-5999
DUSP4	-6287
RPS27A	-6938
MAPK9	-7068
IRF7	-8657
MAPK8	-9428
IRAK2	-9548
CUL1	-11330
RPS6KA5	-11594
NOD1	-12263

---

Programmed Cell Death

Programmed Cell Death

	862
set	Programmed Cell Death
setSize	180
pANOVA	1.26e-10
s.dist	0.278
p.adjustANOVA	3.99e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H1-2	9491
VIM	9394
LMNB1	9345
SDCBP	9311
YWHAG	9264
CD14	9097
YWHAE	9045
TLR4	9016
APAF1	9015
PRKCD	9008
FLOT1	8959
MAPK3	8953
LY96	8795
GSN	8749
BCL2L1	8700
HMGB2	8671
BMX	8664
YWHAH	8649
PSMB7	8485
TFDP1	8470

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H1-2	9491
VIM	9394
LMNB1	9345
SDCBP	9311
YWHAG	9264
CD14	9097
YWHAE	9045
TLR4	9016
APAF1	9015
PRKCD	9008
FLOT1	8959
MAPK3	8953
LY96	8795
GSN	8749
BCL2L1	8700
HMGB2	8671
BMX	8664
YWHAH	8649
PSMB7	8485
TFDP1	8470
FLOT2	8415
PSMD4	8402
UNC5A	8399
TNFRSF10B	8321
PSME3	8251
PAK2	8185
PPP3R1	8175
PSMB5	8101
STAT3	8098
PSMD6	7846
DBNL	7749
CASP9	7685
PSMD9	7620
CFLAR	7610
MAPK1	7493
H1-0	7492
ROCK1	7489
PSMD2	7411
BCL2L11	7384
PSMA1	7329
MLKL	7316
PSMD1	7241
DAPK2	7237
PSMB3	7171
PSMA7	7096
PSMC1	7021
DAPK1	6924
BAD	6892
PSMB6	6813
PELI1	6715
SEPTIN4	6703
PSMF1	6659
UBB	6639
PSMC6	6635
BCAP31	6565
PSMD12	6556
PDCD6IP	6528
STK24	6487
CTNNB1	6408
YWHAB	6385
E2F1	6343
TICAM2	6335
TICAM1	6307
PSMD11	6231
BID	6020
PSMA6	5970
PSMD7	5963
DYNLL1	5952
PSMD13	5948
BAX	5916
PSMD8	5757
ADD1	5704
FADD	5641
YWHAZ	5624
TP53BP2	5532
PSMA2	5339
APIP	4962
CARD8	4726
BIRC2	4692
PLEC	4633
PSMD3	4618
DAPK3	4514
PTK2	4462
UBC	4439
BMF	4375
SEM1	4348
NMT1	4328
RIPK3	4217
TJP2	4142
CDC37	4096
PSMB2	4084
LMNA	3887
FAS	3712
CLSPN	3640
AKT1	3614
PSMD5	3426
PSMB1	3374
DFFA	3371
APC	3240
TNFSF10	3093
DNM1L	3015
OMA1	2947
UNC5B	2809
OPA1	2740
PSMD14	2611
PSMC2	2598
PSMB4	2523
KPNB1	2430
H1-4	2207
UACA	2159
PSMC3	1976
TNFRSF10A	1815
SFN	1615
PSMD10	1559
XIAP	1407
HSP90AA1	1326
KPNA1	1296
UBA52	1121
ACIN1	862
AKT2	433
APPL1	336
CASP7	55
HMGB1	-252
BAK1	-309
TRADD	-556
PSMA4	-616
CASP3	-632
C1QBP	-822
PSMC5	-863
STUB1	-1032
CYCS	-1334
DSP	-1812
OCLN	-2327
CASP6	-2831
PSMB8	-3076
DYNLL2	-3980
BCL2	-4704
TP73	-4754
CDKN2A	-5236
PSMA3	-5285
MAPT	-5437
FNTA	-5724
PSMB10	-5735
PSMA5	-6053
PSME4	-6087
TJP1	-6374
DIABLO	-6393
DFFB	-6836
RPS27A	-6938
OGT	-7119
YWHAQ	-7340
PSMA8	-7606
BBC3	-7864
SATB1	-7905
AVEN	-8133
GAS2	-8542
ARHGAP10	-8847
PSMC4	-9127
MAPK8	-9428
PSME1	-9991
PSME2	-10336
TP63	-10842
STK26	-10888
TP53	-10893
PMAIP1	-10986
RIPK1	-11074
BIRC3	-11125
PSMB9	-11324
CASP8	-11336
SPTAN1	-11426
CDH1	-11500
PPP1R13B	-11636
TRAF2	-11746
AKT3	-11849
PPP3CC	-12126
PRKCQ	-12127
MAGED1	-12295
GZMB	-12361
TFDP2	-12364
FASLG	-12371

---

Signaling by NTRK1 (TRKA)

Signaling by NTRK1 (TRKA)

	1119
set	Signaling by NTRK1 (TRKA)
setSize	101
pANOVA	1.31e-10
s.dist	0.37
p.adjustANOVA	4.07e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GRB2	9304
DUSP3	9280
RIT1	9121
MAPK14	9104
MAP2K1	9063
PIK3CB	9038
CLTC	9000
MAPK3	8953
CRK	8906
FOSL1	8788
AP2M1	8627
CDK5	8616
IRS2	8569
RALB	8414
MAPKAPK3	8382
CLTA	8376
RHOA	8319
PPP2CA	8234
LYL1	8221
STAT3	8098

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GRB2	9304
DUSP3	9280
RIT1	9121
MAPK14	9104
MAP2K1	9063
PIK3CB	9038
CLTC	9000
MAPK3	8953
CRK	8906
FOSL1	8788
AP2M1	8627
CDK5	8616
IRS2	8569
RALB	8414
MAPKAPK3	8382
CLTA	8376
RHOA	8319
PPP2CA	8234
LYL1	8221
STAT3	8098
AP2S1	8026
MEF2A	8009
PPP2CB	7712
RPS6KA1	7695
TRIB1	7643
MAPK1	7493
RAP1A	7305
AP2A2	7257
SRF	7079
KIDINS220	7069
DNM3	7045
AP2A1	6832
JUNB	6806
MAP2K2	6794
YWHAB	6385
EP300	6129
DNM2	6089
ATF1	5706
FOS	5460
NRAS	5363
PIK3R2	5010
ID1	4927
PIK3CA	4629
SGK1	4595
PPP2R1A	4589
DUSP6	4357
SHC2	4183
SHC1	4161
MAPKAPK2	4054
SHC3	3974
CRKL	3966
MAP2K5	3940
MAPK13	3865
MAPK11	3826
KRAS	3702
DNM1	3587
DNAL4	3398
ADORA2A	3293
EGR1	3124
RPS6KA2	3087
RPS6KA3	2973
RALA	2710
PPP2R5D	2421
ATF2	2085
IRS1	1741
JUND	1549
FOSB	1368
NAB1	1342
BRAF	1308
VRK3	1281
TF	1102
ELK1	1040
REST	865
EGR3	44
PPP2R1B	-241
MEF2C	-293
MAPK12	-1074
CDK5R1	-1089
TCF12	-1233
MAPK7	-1337
CREB1	-1378
EGR2	-1435
AP2B1	-2709
MEF2D	-3094
DUSP7	-3211
HRAS	-3382
FRS2	-3433
CHD4	-4515
SOS1	-5700
DUSP4	-6287
NTRK1	-8193
TPH1	-8640
SRC	-8820
PIK3R1	-9505
ID3	-9614
RAPGEF1	-9826
NAB2	-10400
ID2	-10969
PLCG1	-11120
RPS6KA5	-11594
RALGDS	-12140

---

Toll Like Receptor 9 (TLR9) Cascade

Toll Like Receptor 9 (TLR9) Cascade

	1244
set	Toll Like Receptor 9 (TLR9) Cascade
setSize	92
pANOVA	2.03e-10
s.dist	0.383
p.adjustANOVA	6.16e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
DUSP3	9280
APP	9177
MAPK14	9104
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
MAP2K6	8887
LY96	8795
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966
PELI3	7716

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
DUSP3	9280
APP	9177
MAPK14	9104
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
MAP2K6	8887
LY96	8795
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966
PELI3	7716
PPP2CB	7712
RPS6KA1	7695
MAPK1	7493
TAB2	6964
MAP2K4	6866
NFKBIA	6807
PELI1	6715
UBB	6639
TICAM2	6335
TICAM1	6307
NFKB1	6277
FBXW11	6196
MAP3K8	6160
IRAK1	6131
ATF1	5706
TAB1	5681
UBE2V1	5637
TNIP2	5552
FOS	5460
IKBKG	5377
MAP3K1	5121
ECSIT	4918
EEA1	4641
PPP2R1A	4589
UBC	4439
DUSP6	4357
MAPK10	4325
SKP1	4287
MAPKAPK2	4054
MAPK11	3826
JUN	3722
TAB3	3160
RPS6KA2	3087
RPS6KA3	2973
PPP2R5D	2421
MAP3K7	2395
ATF2	2085
UBE2N	1936
MAP2K7	1654
PIK3C3	1619
AGER	1294
VRK3	1281
UBA52	1121
ELK1	1040
RIPK2	1025
NKIRAS1	375
NFKBIB	-152
TRAF6	-229
PPP2R1B	-241
HMGB1	-252
MEF2C	-293
TLR7	-625
NFKB2	-1165
MAPK7	-1337
CREB1	-1378
RELA	-1803
DUSP7	-3211
PIK3R4	-4062
RBSN	-4542
BTRC	-4924
IKBKB	-5386
S100B	-5457
TLR9	-5999
DUSP4	-6287
RPS27A	-6938
MAPK9	-7068
IRF7	-8657
MAPK8	-9428
IRAK2	-9548
CUL1	-11330
RPS6KA5	-11594
NOD1	-12263

---

Translocation of ZAP-70 to Immunological synapse

Translocation of ZAP-70 to Immunological synapse

	1280
set	Translocation of ZAP-70 to Immunological synapse
setSize	24
pANOVA	2.81e-10
s.dist	-0.744
p.adjustANOVA	8.34e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CD247	-12345
HLA-DPA1	-12316
HLA-DPB1	-12248
HLA-DRA	-12009
TRBC1	-12006
HLA-DQA1	-11992
ZAP70	-11949
LCK	-11838
CD3G	-11526
TRAC	-11482
CD3D	-11401
CD3E	-11302
TRBV12-3	-10436
TRAV19	-9915
TRAV29DV5	-9673
TRBV7-9	-9539
HLA-DQB2	-9401
HLA-DRB1	-8075
TRAV8-4	-7261
HLA-DQB1	-6416

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CD247	-12345
HLA-DPA1	-12316
HLA-DPB1	-12248
HLA-DRA	-12009
TRBC1	-12006
HLA-DQA1	-11992
ZAP70	-11949
LCK	-11838
CD3G	-11526
TRAC	-11482
CD3D	-11401
CD3E	-11302
TRBV12-3	-10436
TRAV19	-9915
TRAV29DV5	-9673
TRBV7-9	-9539
HLA-DQB2	-9401
HLA-DRB1	-8075
TRAV8-4	-7261
HLA-DQB1	-6416
CD4	-5406
HLA-DRB5	-4971
HLA-DQA2	-4806
PTPN22	-1208

---

RHO GTPases Activate WASPs and WAVEs

RHO GTPases Activate WASPs and WAVEs

	890
set	RHO GTPases Activate WASPs and WAVEs
setSize	35
pANOVA	4.57e-10
s.dist	0.609
p.adjustANOVA	1.33e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
WASF1	9520
GRB2	9304
CYFIP1	9265
ARPC1B	9259
ACTB	9011
MAPK3	8953
ARPC1A	8894
RAC1	8793
ARPC5	8686
ACTG1	8562
WAS	8560
WASF2	8369
ARPC3	8277
ACTR2	7870
ACTR3	7818
NCKAP1L	7673
CDC42	7537
ARPC4	7516
MAPK1	7493
NCKAP1	7462

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
WASF1	9520
GRB2	9304
CYFIP1	9265
ARPC1B	9259
ACTB	9011
MAPK3	8953
ARPC1A	8894
RAC1	8793
ARPC5	8686
ACTG1	8562
WAS	8560
WASF2	8369
ARPC3	8277
ACTR2	7870
ACTR3	7818
NCKAP1L	7673
CDC42	7537
ARPC4	7516
MAPK1	7493
NCKAP1	7462
ARPC2	7390
BTK	7206
ABI1	7082
BRK1	7032
WASF3	6808
WIPF2	5713
PTK2	4462
WIPF1	569
NCKIPSD	328
WASL	299
ABL1	226
BAIAP2	-215
CYFIP2	-10367
ABI2	-10915
NCK1	-11454

---

Intra-Golgi and retrograde Golgi-to-ER traffic

Intra-Golgi and retrograde Golgi-to-ER traffic

	572
set	Intra-Golgi and retrograde Golgi-to-ER traffic
setSize	179
pANOVA	5.04e-10
s.dist	0.269
p.adjustANOVA	1.39e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PLIN3	9437
ARF4	9191
PLA2G4A	9180
DCTN2	9157
KDELR1	9142
ARF1	9064
RAB1A	9052
CUX1	8986
STX10	8921
GALNT2	8843
NSF	8829
BICD2	8746
TGOLN2	8714
CAPZA2	8597
DCTN4	8387
COPA	8366
RAB1B	8313
KIF3C	8306
KIF5B	8239
VAMP3	8222

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PLIN3	9437
ARF4	9191
PLA2G4A	9180
DCTN2	9157
KDELR1	9142
ARF1	9064
RAB1A	9052
CUX1	8986
STX10	8921
GALNT2	8843
NSF	8829
BICD2	8746
TGOLN2	8714
CAPZA2	8597
DCTN4	8387
COPA	8366
RAB1B	8313
KIF3C	8306
KIF5B	8239
VAMP3	8222
KIF1B	8184
RAB6A	8148
CAPZA1	8135
CAPZB	8015
TMED7	7950
MAN1A1	7927
STX6	7906
COPB2	7902
ARF5	7885
RAB18	7801
KIF1C	7799
DYNC1I2	7735
ARF3	7732
KDELR2	7728
ACTR10	7605
COPG2	7594
VPS54	7568
COPG1	7509
NAA38	7435
KLC3	7377
COPB1	7321
DCTN6	7300
RAB33B	7267
TMED9	7167
STX5	7166
IGF2R	7149
RAB39A	7113
SURF4	7058
ACTR1A	7002
PAFAH1B2	6942
DYNC1LI1	6941
COPE	6896
RIC1	6824
MAN2A2	6625
GALNT1	6508
RAB43	6433
SNAP29	6390
CYTH4	6085
RAB6B	6053
TMED2	6052
KIF13B	5998
DCTN3	5994
DYNLL1	5952
SEC22B	5873
RAB3GAP1	5768
RAB36	5636
ARCN1	5580
KLC1	5523
KIF23	5510
PAFAH1B1	5470
GOLGA5	5322
VTI1A	5302
GOLIM4	5271
YKT6	5205
KIF20A	5096
DCTN1	5078
AGPAT3	4809
STX18	4648
RGP1	4538
RABEPK	4434
USP6NL	4433
RAB3GAP2	4429
PAFAH1B3	4417
DYNC1LI2	4273
COG7	4269
KIF9	4253
DYNC1I1	4187
NAPG	4139
RAB9A	4088
COPZ1	4035
KIF3B	3740
STX16	3717
ARFGAP3	3714
KIF4A	3585
VAMP4	3191
RACGAP1	2848
KIF16B	2785
GCC1	2730
TMED3	2720
KIF27	2549
TMF1	2535
VPS45	2496
GOLGA1	2415
NAPA	1432
KIF6	1147
USE1	938
KIF11	787
KIF2C	726
CYTH2	442
SYS1	386
CENPE	332
TMED10	323
NBAS	208
ZW10	31
COG4	-6
KIF18B	-143
GOSR1	-182
KIFC1	-249
VPS53	-341
COG8	-346
TRIP11	-579
SCOC	-885
KIF2A	-1069
MAN2A1	-1349
GOSR2	-1456
KIFC2	-1642
ARFGAP1	-1942
MAN1A2	-2055
KDELR3	-2117
KIF18A	-2742
NAPB	-2780
ARFIP2	-3197
KIF15	-3249
COG5	-3259
VPS52	-3619
RAB41	-3974
DYNLL2	-3980
GOLGA4	-4064
DCTN5	-4086
GBF1	-4290
KIF26A	-4925
ARL1	-5063
COG3	-5426
ARFGAP2	-5786
COG6	-5811
RAB9B	-6552
VPS51	-6584
KIF21B	-6702
KIF28P	-6770
MAN1C1	-6804
BICD1	-7365
BET1L	-7405
ARFRP1	-7561
BNIP1	-7588
DYNC1H1	-7685
GCC2	-7725
KIF20B	-7822
COG2	-7917
CYTH3	-8200
KLC4	-8376
M6PR	-8519
KIFAP3	-8619
KIF5C	-8865
KIF5A	-8869
KLC2	-9059
NAA30	-9696
RAB30	-9844
RINT1	-10112
COPZ2	-10863
RHOBTB3	-11172
NAA35	-11524
KIF26B	-11663
KIF19	-11733
KIF21A	-11837
KIF3A	-11972
PLA2G6	-12122
COG1	-12125
CYTH1	-12314
KIF22	-12358

---

Gene expression (Transcription)

Gene expression (Transcription)

	445
set	Gene expression (Transcription)
setSize	1332
pANOVA	5.27e-10
s.dist	-0.101
p.adjustANOVA	1.39e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FASLG	-12371
TFDP2	-12364
RUNX3	-12352
ERBB2	-12320
SUV39H1	-12319
NFATC2	-12294
DNMT1	-12257
ZNF599	-12232
PTPN4	-12220
RAD1	-12206
MYBL1	-12195
GATA3	-12191
NDC1	-12173
ZNF287	-12168
ZNF3	-12165
RBBP7	-12155
YES1	-12142
PRKCQ	-12127
AUTS2	-12089
ZNF530	-12068

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FASLG	-12371.0
TFDP2	-12364.0
RUNX3	-12352.0
ERBB2	-12320.0
SUV39H1	-12319.0
NFATC2	-12294.0
DNMT1	-12257.0
ZNF599	-12232.0
PTPN4	-12220.0
RAD1	-12206.0
MYBL1	-12195.0
GATA3	-12191.0
NDC1	-12173.0
ZNF287	-12168.0
ZNF3	-12165.0
RBBP7	-12155.0
YES1	-12142.0
PRKCQ	-12127.0
AUTS2	-12089.0
ZNF530	-12068.0
MDC1	-12059.0
WRN	-12047.0
TP53RK	-12040.0
PHF19	-12016.0
ZNF74	-12012.0
RPA1	-12004.0
MOV10	-11991.0
PRR5	-11985.0
RORA	-11979.0
ANAPC1	-11962.0
ZNF461	-11956.0
FANCI	-11927.0
ZNF33B	-11911.0
ZNF549	-11908.0
ZNF250	-11889.0
DLL1	-11885.0
SMAD7	-11872.0
GLS	-11862.0
NUAK1	-11853.0
AKT3	-11849.0
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MDM4	-1230.0
H2AZ2	-1209.0
CDK5R1	-1089.0
STUB1	-1032.0
ZNF627	-1022.0
AGO3	-1011.0
INTS5	-1001.0
ZNF562	-962.0
TCEA1	-943.0
ZNF565	-941.0
GPS2	-889.0
PSMC5	-863.0
MED6	-842.0
RANBP2	-820.0
SNAPC4	-815.0
TSC2	-804.0
TSN	-800.0
FKBP6	-789.0
UBE2I	-764.0
BRF2	-745.0
SKIL	-725.0
MOBP	-714.0
RRAGB	-713.0
PCGF6	-689.0
ZNF558	-678.0
CDC27	-651.0
PSMA4	-616.0
NPPA	-584.0
MAML2	-582.0
MBD3	-528.0
PABPN1	-526.0
ZNF716	-489.0
TTF1	-328.0
MEF2C	-293.0
PPP2R1B	-241.0
MED14	-203.0
RRM2	-183.0
ZNF587	-164.0
ZNF200	-154.0
HUS1	-145.0
ZNF222	-84.0
ZNF347	-31.0
ARID4B	-27.0
BRD7	-10.0
LEO1	39.0
MT-CO3	40.0
MT-CO2	48.0
KMT2C	63.0
WDR61	77.0
COX16	132.0
WDR5	155.0
KLF4	157.0
UHRF1	170.0
INTS12	172.0
APOE	218.0
MED7	224.0
ABL1	226.0
TCF7L1	275.0
ZNF100	276.0
TRIAP1	281.0
MYB	302.0
CSTF3	309.0
ZNF776	367.0
NFIB	369.0
NELFB	374.0
MLST8	376.0
CSF1R	394.0
POLR2I	396.0
PPP1R13L	399.0
AKT2	433.0
PLAGL1	446.0
CCNB1	467.0
NR3C1	511.0
YY1	537.0
SNAPC1	549.0
COX7C	564.0
CCNA1	585.0
HDAC1	587.0
ELL3	621.0
SNRPE	628.0
CLDN5	650.0
MT-CO1	684.0
BANP	687.0
COX6C	706.0
SETD1B	736.0
INTS1	766.0
NUP62	769.0
CCNH	774.0
KAT6A	794.0
PPARA	813.0
AURKB	846.0
THOC2	911.0
RBBP5	1037.0
ZNF429	1053.0
MAGOH	1054.0
UBA52	1121.0
RPRD1B	1159.0
KMT2B	1179.0
GCK	1193.0
TAF9	1250.0
U2AF1	1287.0
PRKAB1	1302.0
KAT5	1314.0
ITCH	1318.0
ZNF394	1319.0
PRKAA1	1322.0
HSP90AA1	1326.0
ZKSCAN5	1336.0
HDAC9	1359.0
AFF4	1369.0
THRB	1429.0
MED31	1462.0
POU2F1	1537.0
CDK1	1540.0
TPX2	1551.0
PSMD10	1559.0
ATXN3	1601.0
SFN	1615.0
POLR2C	1616.0
ELF1	1630.0
SNRPG	1646.0
SNRPD3	1675.0
CCNA2	1685.0
KCTD15	1758.0
TNFRSF10A	1815.0
PVALB	1839.0
NR1I3	1855.0
CCNC	1877.0
CAMK2G	1921.0
ZNF658B	1948.0
ZNF613	1957.0
CAV1	1969.0
PSMC3	1976.0
PRKAG2	2015.0
MED12	2034.0
CBFB	2078.0
ATF2	2085.0
CNOT11	2102.0
TAF7	2139.0
OPRM1	2161.0
ZKSCAN1	2166.0
CBX4	2222.0
NBN	2267.0
CHM	2273.0
HDAC10	2280.0
GTF2E1	2287.0
STK11	2289.0
MYC	2304.0
SARNP	2436.0
SRSF1	2514.0
PSMB4	2523.0
MED13	2533.0
PSMC2	2598.0
MYBL2	2601.0
ELF2	2606.0
PSMD14	2611.0
DEK	2676.0
GTF2A1	2713.0
SLU7	2727.0
NRBP1	2786.0
SLC38A9	2807.0
POMC	2855.0
E2F8	2856.0
ZNF471	2869.0
CCNK	2877.0
ZNF586	2878.0
SUPT4H1	2890.0
CDC26	2923.0
ZNF770	2964.0
GTF2H2	2984.0
AGO2	2995.0
VENTX	3057.0
NUP37	3074.0
GATAD2A	3075.0
HDAC8	3079.0
MED17	3084.0
RNGTT	3088.0
RAD9B	3090.0
NUP98	3101.0
BTG2	3111.0
DDX21	3113.0
KMT2D	3203.0
HTT	3209.0
MED4	3215.0
THOC6	3225.0
MYO1C	3310.0
SESN2	3311.0
AURKA	3330.0
ZNF445	3333.0
CTR9	3344.0
PSMB1	3374.0
CPSF7	3391.0
CREBBP	3423.0
PSMD5	3426.0
PRDX2	3428.0
PAF1	3478.0
ZNF189	3487.0
NFYA	3506.0
POLR2G	3508.0
RNF2	3513.0
GTF2B	3515.0
RTF1	3526.0
ZNF205	3530.0
SURF1	3532.0
ERCC2	3547.0
SSU72	3574.0
PRMT5	3600.0
AKT1	3614.0
TAF8	3620.0
U2AF2	3663.0
KRAS	3702.0
FAS	3712.0
JUN	3722.0
ZNF668	3725.0
BIRC5	3738.0
ZNF667	3739.0
DPY30	3757.0
SRSF4	3814.0
MAPK11	3826.0
TMEM219	3845.0
NELFE	3860.0
GTF2H5	3874.0
ZNF354A	3889.0
PIWIL4	3916.0
RBX1	3934.0
ZNF747	3949.0
CSNK2B	3969.0
PPARGC1A	3988.0
ZNF333	4007.0
CBX6	4033.0
PSMB2	4084.0
COX4I1	4191.0
CASP1	4224.0
CTSL	4231.0
MAX	4243.0
POU2F2	4251.0
TSNAX	4264.0
SKP1	4287.0
INTS10	4291.0
DNMT3B	4294.0
MDM2	4312.0
SEM1	4348.0
KCTD6	4371.0
SOD2	4390.0
MED26	4395.0
TACO1	4406.0
ING2	4415.0
UBC	4439.0
LAMTOR4	4441.0
COX7B	4465.0
CDKN1A	4511.0
NUP50	4521.0
SUDS3	4526.0
TBL1XR1	4556.0
RPRD1A	4573.0
IPO8	4588.0
PPP2R1A	4589.0
SGK1	4595.0
POLR2F	4604.0
PSMD3	4618.0
NDRG1	4647.0
HDAC3	4673.0
ZNF552	4685.0
ZNF20	4697.0
NOTCH1	4704.0
HDAC5	4710.0
SMARCA4	4733.0
UBE2S	4746.0
ZNF774	4747.0
HDAC11	4756.0
CNOT6	4799.0
DLX6	4817.0
CBX3	4825.0
CRCP	4826.0
ARID1A	4830.0
AR	4840.0
CCNG1	4881.0
ZNF282	4892.0
SMAD2	4905.0
DDIT3	4906.0
RFC2	4948.0
GTF2F1	4951.0
RRAGC	4954.0
CDC25C	4969.0
H2AC20	4972.0
NR2F6	4984.0
SAP18	5004.0
ELL	5009.0
CDC73	5020.0
SNAPC2	5038.0
ZNF775	5041.0
MAPKAP1	5057.0
CTSK	5059.0
COX6A1	5095.0
UBE2C	5101.0
GPRIN1	5131.0
CCNE2	5143.0
TGFB1	5153.0
RAE1	5164.0
SAP30L	5199.0
SNW1	5201.0
CDK7	5211.0
CRADD	5216.0
CASC3	5242.0
NFIX	5243.0
NOTCH2	5272.0
MED16	5278.0
POLR2L	5305.0
H2BC15	5312.0
PTPN11	5314.0
CNOT3	5320.0
SLBP	5337.0
PSMA2	5339.0
H2BC9	5394.0
MAML1	5404.0
ALYREF	5432.0
GTF2F2	5434.0
CBX8	5448.0
FOS	5460.0
USP9X	5464.0
PRKAG1	5476.0
HDAC2	5482.0
TP53BP2	5532.0
EAF1	5533.0
RYBP	5535.0
PBRM1	5566.0
G6PC	5568.0
YWHAZ	5624.0
AGO1	5654.0
COX6B1	5667.0
INTS6	5673.0
PF4	5707.0
PTPN1	5722.0
KDM5B	5736.0
SEC13	5748.0
RNF111	5749.0
PSMD8	5757.0
GTF2E2	5767.0
PRELID1	5790.0
HIPK1	5855.0
NCOR1	5887.0
IWS1	5894.0
BAX	5916.0
ESRRA	5943.0
PSMD13	5948.0
ZNF213	5950.0
THBS1	5951.0
PSMD7	5963.0
PSMA6	5970.0
STEAP3	5996.0
ASH2L	6001.0
ZNF385A	6014.0
BID	6020.0
H2AZ1	6036.0
HIPK2	6078.0
HDAC7	6122.0
EP300	6129.0
IRAK1	6131.0
PDPK1	6136.0
ANAPC11	6161.0
COX5A	6168.0
CTDP1	6180.0
CSNK2A1	6199.0
TIGAR	6204.0
COX5B	6207.0
MED25	6209.0
PSMD11	6231.0
INTS3	6232.0
RRAGA	6244.0
BRCA1	6248.0
NFKB1	6277.0
GP1BA	6279.0
GPI	6284.0
THOC7	6293.0
E2F4	6300.0
USP7	6323.0
LSM10	6338.0
E2F1	6343.0
YWHAB	6385.0
CSNK2A2	6388.0
FOXO4	6391.0
CTNNB1	6408.0
RARA	6429.0
CITED2	6457.0
TP53INP1	6458.0
NDUFA4	6459.0
TAL1	6518.0
SREBF1	6539.0
PSMD12	6556.0
POLR1D	6566.0
MBD2	6581.0
CLP1	6589.0
CPSF3	6602.0
EAF2	6605.0
COX8A	6611.0
CCNG2	6629.0
GSK3B	6634.0
PSMC6	6635.0
UBB	6639.0
PSMF1	6659.0
POLR2J	6671.0
TDG	6672.0
PLK3	6680.0
ZNF230	6689.0
H3C15	6699.5
TWIST2	6721.0
MED20	6743.0
UBE2E1	6759.0
SATB2	6781.0
RRM2B	6798.0
CDC40	6801.0
JUNB	6806.0
PSMB6	6813.0
SUMO1	6889.0
ZNF710	6900.0
SMARCD2	6914.0
RMI1	6947.0
GTF3C6	6962.0
PSMC1	7021.0
PRDX1	7030.0
GTF2A2	7066.0
PSMA7	7096.0
PRKCB	7097.0
TAF10	7110.0
PAPOLA	7153.0
PSMB3	7171.0
ZNF267	7203.0
TAF13	7217.0
THOC5	7235.0
PSMD1	7241.0
JARID2	7243.0
ZNF143	7265.0
POLDIP3	7269.0
EIF4A3	7273.0
H2BC17	7285.0
ELOA	7312.0
PSMA1	7329.0
BCL2L11	7384.0
H2BC4	7389.0
PSMD2	7411.0
NR1H2	7415.0
SRSF9	7422.0
ZFHX3	7425.0
VEGFA	7467.0
ELOB	7482.0
SERPINE1	7483.0
CCND3	7487.0
MAPK1	7493.0
RXRA	7495.0
ELOC	7519.0
RUNX1	7529.0
MED8	7535.0
POLR2E	7563.0
LAMTOR2	7567.0
ZNF746	7573.0
LAMTOR3	7574.0
PSMD9	7620.0
NFYC	7653.0
ITGA5	7659.0
RHEB	7669.0
MYL9	7703.0
PPP2CB	7712.0
COX7A2L	7719.0
PPM1D	7810.0
MLLT1	7825.0
ELL2	7828.0
SMAD6	7835.0
CPSF2	7838.0
CITED4	7844.0
PSMD6	7846.0
NEDD4L	7875.0
TBL1X	7887.0
NOTCH3	7899.0
TET3	7905.0
H2BC11	7912.0
NUP214	7921.0
H2AC6	7934.0
TNFRSF10C	7960.0
TOP3A	7973.0
TAF12	7977.0
NCOR2	7985.0
CEBPB	7997.0
NABP1	8001.0
H2BC5	8003.0
KMT5A	8005.0
NRBF2	8076.0
INTS8	8079.0
TET2	8081.0
PSMB5	8101.0
LBR	8102.0
NFIA	8117.0
TXNRD1	8192.0
SP1	8193.0
PPM1A	8200.0
CNOT8	8227.0
PPP2CA	8234.0
DICER1	8238.0
PSME3	8251.0
TXN	8285.0
SAP30	8303.0
LMO2	8307.0
TNFRSF10B	8321.0
VDR	8348.0
PSMD4	8402.0
GATA1	8410.0
PTEN	8460.0
TFDP1	8470.0
PSMB7	8485.0
NFIC	8486.0
LAMTOR5	8498.0
SMAD1	8511.0
PRDX5	8531.0
NR6A1	8553.0
ARID3A	8584.0
CDK5	8616.0
UBE2D3	8640.0
YWHAH	8649.0
H3-3A	8661.0
SMARCD3	8668.0
FOXO3	8682.0
RB1	8707.0
JAG1	8743.0
LGALS3	8752.0
RRAGD	8753.0
RBPJ	8770.0
NUP58	8820.0
CDKN2B	8836.0
MAP2K6	8887.0
TGFA	8889.0
SPI1	8891.0
ITGA2B	8893.0
PINK1	8941.0
MAPK3	8953.0
MAML3	8957.0
HDAC4	8960.0
ANAPC15	8968.0
TP53I3	8979.0
RETN	8998.0
ZNF697	9002.0
G6PD	9004.0
ACTB	9011.0
APAF1	9015.0
CARM1	9020.0
SLC2A3	9021.0
PHC2	9043.0
YWHAE	9045.0
H2BC12	9051.0
AGO4	9070.0
TNFRSF10D	9072.0
GADD45A	9083.0
FKBP5	9091.0
MAPK14	9104.0
CAT	9123.0
BCL6	9175.0
UBE2D1	9187.0
GSR	9235.0
YWHAG	9264.0
H2BC21	9283.0
BNIP3L	9329.0
H2AJ	9374.0
NLRC4	9406.0
LAMTOR1	9411.0
PRKACA	9429.0
NFE2	9431.0
SOCS3	9476.0
CR1	9486.0
TDRD9	9519.0
PPARG	9522.0

---

MyD88 cascade initiated on plasma membrane

MyD88 cascade initiated on plasma membrane

	686
set	MyD88 cascade initiated on plasma membrane
setSize	82
pANOVA	5.31e-10
s.dist	0.397
p.adjustANOVA	1.39e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
DUSP3	9280
TLR5	9201
APP	9177
MAPK14	9104
MAP2K1	9063
MAPK3	8953
MAP2K6	8887
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966
PELI3	7716
PPP2CB	7712
RPS6KA1	7695

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
DUSP3	9280
TLR5	9201
APP	9177
MAPK14	9104
MAP2K1	9063
MAPK3	8953
MAP2K6	8887
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966
PELI3	7716
PPP2CB	7712
RPS6KA1	7695
MAPK1	7493
TAB2	6964
MAP2K4	6866
NFKBIA	6807
PELI1	6715
UBB	6639
NFKB1	6277
FBXW11	6196
MAP3K8	6160
IRAK1	6131
ATF1	5706
TAB1	5681
UBE2V1	5637
TNIP2	5552
FOS	5460
IKBKG	5377
MAP3K1	5121
ECSIT	4918
PPP2R1A	4589
UBC	4439
DUSP6	4357
MAPK10	4325
SKP1	4287
MAPKAPK2	4054
MAPK11	3826
JUN	3722
TAB3	3160
RPS6KA2	3087
RPS6KA3	2973
PPP2R5D	2421
MAP3K7	2395
ATF2	2085
UBE2N	1936
MAP2K7	1654
AGER	1294
VRK3	1281
UBA52	1121
ELK1	1040
RIPK2	1025
NKIRAS1	375
NFKBIB	-152
TRAF6	-229
PPP2R1B	-241
HMGB1	-252
MEF2C	-293
NFKB2	-1165
MAPK7	-1337
CREB1	-1378
RELA	-1803
TLR10	-2961
DUSP7	-3211
BTRC	-4924
IKBKB	-5386
S100B	-5457
DUSP4	-6287
RPS27A	-6938
MAPK9	-7068
MAPK8	-9428
IRAK2	-9548
CUL1	-11330
RPS6KA5	-11594
NOD1	-12263

---

Toll Like Receptor 10 (TLR10) Cascade

Toll Like Receptor 10 (TLR10) Cascade

	1238
set	Toll Like Receptor 10 (TLR10) Cascade
setSize	82
pANOVA	5.31e-10
s.dist	0.397
p.adjustANOVA	1.39e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
DUSP3	9280
TLR5	9201
APP	9177
MAPK14	9104
MAP2K1	9063
MAPK3	8953
MAP2K6	8887
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966
PELI3	7716
PPP2CB	7712
RPS6KA1	7695

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
DUSP3	9280
TLR5	9201
APP	9177
MAPK14	9104
MAP2K1	9063
MAPK3	8953
MAP2K6	8887
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966
PELI3	7716
PPP2CB	7712
RPS6KA1	7695
MAPK1	7493
TAB2	6964
MAP2K4	6866
NFKBIA	6807
PELI1	6715
UBB	6639
NFKB1	6277
FBXW11	6196
MAP3K8	6160
IRAK1	6131
ATF1	5706
TAB1	5681
UBE2V1	5637
TNIP2	5552
FOS	5460
IKBKG	5377
MAP3K1	5121
ECSIT	4918
PPP2R1A	4589
UBC	4439
DUSP6	4357
MAPK10	4325
SKP1	4287
MAPKAPK2	4054
MAPK11	3826
JUN	3722
TAB3	3160
RPS6KA2	3087
RPS6KA3	2973
PPP2R5D	2421
MAP3K7	2395
ATF2	2085
UBE2N	1936
MAP2K7	1654
AGER	1294
VRK3	1281
UBA52	1121
ELK1	1040
RIPK2	1025
NKIRAS1	375
NFKBIB	-152
TRAF6	-229
PPP2R1B	-241
HMGB1	-252
MEF2C	-293
NFKB2	-1165
MAPK7	-1337
CREB1	-1378
RELA	-1803
TLR10	-2961
DUSP7	-3211
BTRC	-4924
IKBKB	-5386
S100B	-5457
DUSP4	-6287
RPS27A	-6938
MAPK9	-7068
MAPK8	-9428
IRAK2	-9548
CUL1	-11330
RPS6KA5	-11594
NOD1	-12263

---

Toll Like Receptor 5 (TLR5) Cascade

Toll Like Receptor 5 (TLR5) Cascade

	1242
set	Toll Like Receptor 5 (TLR5) Cascade
setSize	82
pANOVA	5.31e-10
s.dist	0.397
p.adjustANOVA	1.39e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
DUSP3	9280
TLR5	9201
APP	9177
MAPK14	9104
MAP2K1	9063
MAPK3	8953
MAP2K6	8887
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966
PELI3	7716
PPP2CB	7712
RPS6KA1	7695

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
DUSP3	9280
TLR5	9201
APP	9177
MAPK14	9104
MAP2K1	9063
MAPK3	8953
MAP2K6	8887
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PELI2	8314
PPP2CA	8234
MYD88	8136
MEF2A	8009
CHUK	7966
PELI3	7716
PPP2CB	7712
RPS6KA1	7695
MAPK1	7493
TAB2	6964
MAP2K4	6866
NFKBIA	6807
PELI1	6715
UBB	6639
NFKB1	6277
FBXW11	6196
MAP3K8	6160
IRAK1	6131
ATF1	5706
TAB1	5681
UBE2V1	5637
TNIP2	5552
FOS	5460
IKBKG	5377
MAP3K1	5121
ECSIT	4918
PPP2R1A	4589
UBC	4439
DUSP6	4357
MAPK10	4325
SKP1	4287
MAPKAPK2	4054
MAPK11	3826
JUN	3722
TAB3	3160
RPS6KA2	3087
RPS6KA3	2973
PPP2R5D	2421
MAP3K7	2395
ATF2	2085
UBE2N	1936
MAP2K7	1654
AGER	1294
VRK3	1281
UBA52	1121
ELK1	1040
RIPK2	1025
NKIRAS1	375
NFKBIB	-152
TRAF6	-229
PPP2R1B	-241
HMGB1	-252
MEF2C	-293
NFKB2	-1165
MAPK7	-1337
CREB1	-1378
RELA	-1803
TLR10	-2961
DUSP7	-3211
BTRC	-4924
IKBKB	-5386
S100B	-5457
DUSP4	-6287
RPS27A	-6938
MAPK9	-7068
MAPK8	-9428
IRAK2	-9548
CUL1	-11330
RPS6KA5	-11594
NOD1	-12263

---

Developmental Biology

Developmental Biology

	281
set	Developmental Biology
setSize	732
pANOVA	1.07e-09
s.dist	0.132
p.adjustANOVA	2.75e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PPARG	9522
CD36	9444
GRB10	9439
PRKACA	9429
NUMB	9414
LAMC1	9387
H2AJ	9374
ST14	9372
CTNNA1	9341
SDCBP	9311
ARHGEF11	9305
GRB2	9304
ITSN1	9289
DSC2	9288
H2BC21	9283
ARPC1B	9259
FES	9237
ALCAM	9230
NCSTN	9186
PLXNC1	9160

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PPARG	9522.0
CD36	9444.0
GRB10	9439.0
PRKACA	9429.0
NUMB	9414.0
LAMC1	9387.0
H2AJ	9374.0
ST14	9372.0
CTNNA1	9341.0
SDCBP	9311.0
ARHGEF11	9305.0
GRB2	9304.0
ITSN1	9289.0
DSC2	9288.0
H2BC21	9283.0
ARPC1B	9259.0
FES	9237.0
ALCAM	9230.0
NCSTN	9186.0
PLXNC1	9160.0
SPTB	9154.0
ACVR1B	9135.0
ZNF467	9118.0
MAPK14	9104.0
FURIN	9075.0
MAP2K1	9063.0
SEMA4A	9060.0
H2BC12	9051.0
CSTA	9039.0
PIK3CB	9038.0
RAP1GAP	9037.0
CARM1	9020.0
ACTB	9011.0
DLG4	9007.0
CLTC	9000.0
CLTCL1	8965.0
MAML3	8957.0
MAPK3	8953.0
MYO10	8918.0
PLXNB3	8915.0
PDLIM7	8911.0
ARPC1A	8894.0
ITGA2B	8893.0
SPI1	8891.0
MAP2K6	8887.0
CEBPD	8816.0
RAC1	8793.0
ADAM10	8791.0
ANK1	8771.0
RBPJ	8770.0
PCSK6	8740.0
ITGA1	8729.0
CSF3R	8687.0
ARPC5	8686.0
FOXO3	8682.0
SMARCD3	8668.0
H3-3A	8661.0
AP2M1	8627.0
BNIP2	8621.0
CDK5	8616.0
SIAH2	8578.0
MYL6	8576.0
IRS2	8569.0
CAPN1	8563.0
ACTG1	8562.0
NR6A1	8553.0
TLN1	8525.0
PSMB7	8485.0
EPHB3	8479.0
TFDP1	8470.0
PSMD4	8402.0
UNC5A	8399.0
CLTA	8376.0
ABLIM3	8354.0
RHOA	8319.0
SOS2	8299.0
CEBPA	8296.0
ITGB3	8291.0
ARPC3	8277.0
PSME3	8251.0
ST8SIA4	8236.0
PAK1	8230.0
CFL1	8186.0
PAK2	8185.0
DPYSL2	8145.0
IL6R	8132.0
CAP1	8111.0
PSMB5	8101.0
GAB2	8099.0
STAT3	8098.0
HMGCR	8094.0
LIMK2	8074.0
SHTN1	8040.0
EIF4G1	8031.0
VASP	8027.0
AP2S1	8026.0
DOK1	8022.0
RDX	8021.0
MEF2A	8009.0
H2BC5	8003.0
CEBPB	7997.0
MAFB	7991.0
NCOR2	7985.0
PSEN1	7961.0
H2AC6	7934.0
H2BC11	7912.0
TBL1X	7887.0
EPAS1	7886.0
ACTR2	7870.0
PSMD6	7846.0
MPZ	7832.0
ACTR3	7818.0
LYN	7809.0
CAPNS1	7729.0
MYL9	7703.0
RPS6KA1	7695.0
ITGA5	7659.0
PSMD9	7620.0
CDK19	7618.0
SPTA1	7595.0
POLR2E	7563.0
TYROBP	7539.0
CDC42	7537.0
MED8	7535.0
RUNX1	7529.0
ELOC	7519.0
ARPC4	7516.0
RXRA	7495.0
MAPK1	7493.0
ROCK1	7489.0
CCND3	7487.0
ELOB	7482.0
PLXND1	7475.0
ETF1	7419.0
PSMD2	7411.0
ARPC2	7390.0
H2BC4	7389.0
CEBPE	7378.0
PSMA1	7329.0
RGMA	7322.0
DOCK1	7314.0
H2BC17	7285.0
HHEX	7283.0
EIF4A3	7273.0
AP2A2	7257.0
PSMD1	7241.0
RPL26L1	7176.0
PSMB3	7171.0
PSMA7	7096.0
DNM3	7045.0
PSMC1	7021.0
PPP3CB	7005.0
PLXNA2	6977.0
ITGA9	6940.0
MYL12A	6899.0
LYPLA2	6848.0
CYP51A1	6844.0
AP2A1	6832.0
PITPNA	6820.0
PSMB6	6813.0
MAP2K2	6794.0
SRGAP1	6744.0
MED20	6743.0
KRT23	6702.0
H3C15	6699.5
SREBF2	6695.0
MYH9	6685.0
POLR2J	6671.0
PSMF1	6659.0
UBB	6639.0
PSMC6	6635.0
GSK3B	6634.0
PSMD12	6556.0
KAZN	6541.0
SREBF1	6539.0
TAL1	6518.0
GSPT1	6475.0
RARA	6429.0
MYO9B	6424.0
KRT80	6411.0
CTNNB1	6408.0
CSNK2A2	6388.0
E2F1	6343.0
APH1B	6280.0
NFKB1	6277.0
PSMD11	6231.0
MED25	6209.0
CSNK2A1	6199.0
SH3KBP1	6173.0
SRGAP2	6171.0
PRKAR2A	6166.0
LGI2	6163.0
ROCK2	6138.0
EFNA4	6133.0
EP300	6129.0
ITGAV	6106.0
LIPN	6095.0
DNM2	6089.0
CLTB	6084.0
MED13L	6077.0
PIK3CD	6046.0
MEF2B	6041.0
H2AZ1	6036.0
ASH2L	6001.0
PSMA6	5970.0
LAMB1	5966.0
PSMD7	5963.0
PSMD13	5948.0
KRT7	5889.0
NCOR1	5887.0
RANBP9	5813.0
NCOA6	5773.0
PSMD8	5757.0
PSENEN	5735.0
GAB1	5679.0
PKP2	5678.0
SCN1B	5668.0
PLXNB1	5639.0
FLI1	5555.0
MSN	5524.0
HDAC2	5482.0
PFN1	5459.0
RPS9	5421.0
MAML1	5404.0
SDC2	5397.0
H2BC9	5394.0
NRAS	5363.0
PABPC1	5351.0
PSMA2	5339.0
ZSWIM8	5329.0
PTPN11	5314.0
H2BC15	5312.0
POLR2L	5305.0
MED16	5278.0
PAGR1	5276.0
CASC3	5242.0
EPHB4	5203.0
SNW1	5201.0
TGFB1	5153.0
SCN5A	5137.0
COL9A3	5126.0
PBX1	5098.0
MYL12B	5088.0
COL6A3	5053.0
KLF5	5051.0
PIK3R2	5010.0
H2AC20	4972.0
NCK2	4934.0
SMAD2	4905.0
VAV3	4894.0
SPAG9	4803.0
CNOT6	4799.0
SLIT1	4769.0
SMARCA4	4733.0
NOTCH1	4704.0
LIMK1	4679.0
HDAC3	4673.0
PIK3CA	4629.0
PSMD3	4618.0
POLR2F	4604.0
TBL1XR1	4556.0
TSC22D1	4541.0
KRT1	4537.0
CDKN1A	4511.0
RPL3L	4503.0
NCOA1	4483.0
PTK2	4462.0
UBC	4439.0
MED18	4396.0
MED26	4395.0
EPHB2	4355.0
SEM1	4348.0
ABL2	4346.0
PRNP	4250.0
CD24	4185.0
ITGA2	4168.0
SHC1	4161.0
APH1A	4133.0
PSMB2	4084.0
PPARGC1A	3988.0
SHC3	3974.0
CSNK2B	3969.0
RBX1	3934.0
FGF2	3920.0
MAPK13	3865.0
ZNF638	3852.0
MAPK11	3826.0
MED22	3802.0
JUN	3722.0
ADGRV1	3708.0
KRAS	3702.0
KDM6A	3633.0
AKT1	3614.0
DNM1	3587.0
KIF4A	3585.0
CACNA1D	3582.0
RRAS	3575.0
NCOA3	3522.0
POLR2G	3508.0
PSMD5	3426.0
CREBBP	3423.0
PIP5K1C	3419.0
PSMB1	3374.0
MED19	3243.0
MED4	3215.0
KMT2D	3203.0
SCN2A	3185.0
ARHGEF12	3166.0
RPS6KA2	3087.0
MED17	3084.0
PKP4	3044.0
PI3	3023.0
RPS6KA3	2973.0
PSPN	2969.0
EFNA1	2933.0
UNC5B	2809.0
DOK4	2804.0
DEK	2676.0
PSMD14	2611.0
PSMC2	2598.0
LPL	2545.0
MED13	2533.0
CUL2	2526.0
PSMB4	2523.0
ONECUT1	2493.0
KCNQ3	2380.0
MYC	2304.0
PTPRC	2240.0
RASA1	2106.0
CBFB	2078.0
RPS27L	2061.0
NANOG	2038.0
MED12	2034.0
RPS6KA4	1987.0
PSMC3	1976.0
CCNC	1877.0
TRIO	1820.0
POU5F1	1756.0
MMP9	1690.0
PPL	1679.0
POLR2C	1616.0
KRT8	1580.0
PSMD10	1559.0
MED31	1462.0
SCN2B	1401.0
NAB1	1342.0
HSP90AA1	1326.0
RHOB	1254.0
LIN28A	1233.0
RELN	1203.0
GCK	1193.0
PRKCA	1132.0
UBA52	1121.0
NCOA2	1092.0
MAGOH	1054.0
RBBP5	1037.0
KRT10	1031.0
COL4A2	970.0
UPF2	964.0
NFASC	866.0
PPARA	813.0
MYH10	653.0
TIAM1	651.0
YY1	537.0
NTN3	478.0
AKT2	433.0
RPS4Y1	424.0
MSI1	402.0
POLR2I	396.0
THRAP3	388.0
CACNB3	370.0
MYB	302.0
WASL	299.0
SLIT3	296.0
ABL1	226.0
MED7	224.0
EPHB6	175.0
KLF4	157.0
WDR5	155.0
KMT2C	63.0
RPL36AL	32.0
RPLP1	19.0
FAM120B	-8.0
CXCR4	-45.0
ITGB1	-94.0
ROBO1	-195.0
MED14	-203.0
RPS24	-263.0
MEF2C	-293.0
ITGA10	-322.0
CNTN2	-344.0
FAU	-362.0
PRSS8	-364.0
EVPL	-473.0
SCN9A	-530.0
MED11	-560.0
MAML2	-582.0
CRMP1	-583.0
CLASP1	-588.0
PSMA4	-616.0
USP33	-821.0
MED6	-842.0
PSMC5	-863.0
DOK2	-952.0
RPL15	-963.0
RPLP0	-1000.0
LAMA1	-1044.0
MAPK12	-1074.0
CDK5R1	-1089.0
RPL8	-1187.0
H2AZ2	-1209.0
TCF12	-1233.0
MAPK7	-1337.0
CREB1	-1378.0
MED28	-1429.0
RPS26	-1430.0
EGR2	-1435.0
RPL28	-1462.0
PAK4	-1475.0
KLK14	-1488.0
RND1	-1545.0
DPPA4	-1564.0
COL6A1	-1605.0
RPL22L1	-1619.0
RPS13	-1749.0
POLR2K	-1783.0
RELA	-1803.0
DSP	-1812.0
RBBP4	-1870.0
RPL9	-1872.0
TRPC6	-1935.0
RPL7	-1955.0
CDK8	-1971.0
RPS8	-2083.0
MEIS1	-2102.0
CLASP2	-2151.0
SCN3A	-2293.0
PFN2	-2339.0
SUZ12	-2409.0
KAT2B	-2414.0
HIF3A	-2519.0
POLR2B	-2523.0
PKNOX1	-2660.0
ENAH	-2707.0
AP2B1	-2709.0
SEMA4D	-2830.0
ONECUT3	-2852.0
RPL27	-2855.0
POLR2H	-2942.0
STX1B	-2952.0
SIAH1	-3000.0
RPL39	-3006.0
PSMB8	-3076.0
POLR2A	-3092.0
MEF2D	-3094.0
RPL23	-3314.0
RPL6	-3354.0
LGI4	-3358.0
ARHGAP35	-3359.0
HRAS	-3382.0
RPL13	-3431.0
FRS2	-3433.0
ANGPTL4	-3469.0
NRCAM	-3496.0
MYH11	-3522.0
SPTBN5	-3531.0
RPL4	-3582.0
RPL29	-3611.0
RPL7A	-3665.0
RPS15	-3673.0
KALRN	-3692.0
COL4A4	-3759.0
PLIN1	-3785.0
TCF4	-3836.0
COL4A3	-3896.0
RPL37A	-3946.0
POLR2D	-4024.0
MED1	-4036.0
STX1A	-4052.0
VAV2	-4055.0
RPS21	-4079.0
PCGF2	-4135.0
PAK3	-4184.0
PRX	-4225.0
NRP2	-4282.0
CACNA1I	-4311.0
LEFTY1	-4360.0
VLDLR	-4385.0
KRT18	-4390.0
RPS2	-4499.0
RPL31	-4541.0
ARHGEF7	-4583.0
CHD9	-4585.0
PTPRA	-4626.0
GPC1	-4627.0
NTN1	-4654.0
RPS16	-4669.0
RPS3A	-4694.0
RPS28	-4713.0
RPL5	-4728.0
RPL22	-4740.0
RGMB	-4805.0
KRT73	-4826.0
SCN8A	-4836.0
ANK3	-4919.0
CD72	-4949.0
EBF1	-4954.0
RPS7	-4968.0
CDK2	-5006.0
KRT72	-5021.0
RPL18	-5080.0
EPHA1	-5111.0
CNTNAP1	-5116.0
CHL1	-5122.0
SPTBN2	-5129.0
RARG	-5153.0
PSMA3	-5285.0
RPL36	-5287.0
FGFR1	-5352.0
JUP	-5353.0
NODAL	-5372.0
RPS6KA6	-5394.0
RPL17	-5431.0
TGS1	-5441.0
RPS14	-5463.0
MED30	-5484.0
PMP22	-5556.0
MAMLD1	-5584.0
TGM1	-5651.0
SRGAP3	-5675.0
RPS5	-5691.0
SOS1	-5700.0
SOX10	-5721.0
PSMB10	-5735.0
RPS15A	-5742.0
CACNB4	-5768.0
AGAP2	-5788.0
RPS10	-5793.0
RPL24	-5799.0
RPL38	-5840.0
MBP	-5848.0
NCBP1	-5853.0
SEMA3A	-5854.0
RPS3	-5914.0
MED21	-5937.0
RPS12	-5987.0
CACNB2	-6006.0
RPL35A	-6015.0
SCN4A	-6037.0
PSMA5	-6053.0
RPL18A	-6070.0
PSME4	-6087.0
CDH4	-6111.0
SALL4	-6112.0
WWTR1	-6131.0
RPS6	-6160.0
EFNB2	-6182.0
RPS17	-6247.0
RPL27A	-6257.0
RPL11	-6261.0
RPL19	-6281.0
RPS4X	-6285.0
RPS23	-6292.0
RPSA	-6323.0
DPYSL4	-6331.0
L1CAM	-6358.0
RPS25	-6365.0
RPL37	-6375.0
RPL21	-6458.0
RPL10	-6534.0
H2BU1	-6555.0
RPL26	-6612.0
RPL10A	-6686.0
RPL32	-6709.0
RPL14	-6710.0
MED23	-6787.0
RPL34	-6802.0
SCN7A	-6803.0
SCN3B	-6831.0
HSP90AB1	-6863.0
RPL41	-6866.0
DSC1	-6927.0
RPS27A	-6938.0
RPS19	-6965.0
RPL30	-7020.0
DRAP1	-7046.0
RPL12	-7053.0
RPLP2	-7087.0
TCF3	-7215.0
ACVR1C	-7219.0
RPS11	-7243.0
TNF	-7308.0
RPL36A	-7376.0
DAG1	-7379.0
MED24	-7387.0
RBM8A	-7393.0
LHX4	-7452.0
PIAS2	-7496.0
PSMA8	-7606.0
PSEN2	-7718.0
RPS18	-7744.0
SCD5	-7756.0
SPTBN1	-7764.0
HOXA3	-7794.0
ZNF335	-7813.0
RET	-7856.0
AJUBA	-7927.0
RPS29	-7940.0
MED29	-7985.0
EFNA3	-8004.0
SEMA6A	-8016.0
LEF1	-8076.0
RPL35	-8092.0
DOK6	-8120.0
NTN4	-8121.0
PLXNA3	-8145.0
ARHGAP39	-8166.0
CDON	-8176.0
RPL13A	-8212.0
HES1	-8266.0
UPF3B	-8288.0
SHANK3	-8296.0
DLG1	-8336.0
SMAD4	-8351.0
PLXNA1	-8506.0
RPL3	-8561.0
MED10	-8579.0
FOXP1	-8600.0
CACNG8	-8680.0
GFRA2	-8689.0
PML	-8693.0
NRP1	-8717.0
CACNA1H	-8721.0
ADAM23	-8734.0
RPL39L	-8805.0
KRT15	-8811.0
MED9	-8812.0
SRC	-8820.0
RPS20	-8886.0
DAB1	-8895.0
EFNA5	-8908.0
SEMA7A	-8986.0
PAXIP1	-8990.0
WNT1	-9014.0
HELZ2	-9045.0
ADAM11	-9112.0
PSMC4	-9127.0
MED27	-9191.0
HOXA1	-9232.0
CTCF	-9253.0
MAGOHB	-9327.0
TRPC3	-9343.0
EED	-9348.0
HOXB2	-9357.0
MAPK8	-9428.0
FOXO1	-9465.0
GIT1	-9471.0
KRTAP5-1	-9478.0
SEMA5A	-9495.0
PIK3R1	-9505.0
NCBP2	-9558.0
RPL23A	-9567.0
FARP2	-9602.0
TRPC1	-9736.0
EZH2	-9741.0
RPS27	-9756.0
COL9A2	-9770.0
MED15	-9778.0
NEO1	-9779.0
GATA2	-9800.0
UPF3A	-9834.0
ABLIM2	-9868.0
LAMA2	-9911.0
WNT10B	-9917.0
PERP	-9973.0
PSME1	-9991.0
EPHB1	-10082.0
ADGRG6	-10172.0
COL6A2	-10206.0
ARHGEF28	-10288.0
LDB1	-10303.0
ROBO3	-10328.0
PSME2	-10336.0
NAB2	-10400.0
GSPT2	-10403.0
ABLIM1	-10430.0
HOXC4	-10441.0
ACVR2B	-10569.0
KMT2A	-10725.0
KAT2A	-10771.0
EFNB1	-10819.0
CACNB1	-10848.0
CACNA1C	-10875.0
HSPA8	-10922.0
HOXB3	-10958.0
NELL2	-11079.0
PLXNA4	-11083.0
PLCG1	-11120.0
ADAM22	-11181.0
HOXB4	-11215.0
CDK4	-11256.0
PSMB9	-11324.0
ACVR2A	-11338.0
RHOC	-11360.0
SPTAN1	-11426.0
RNPS1	-11427.0
EPHA4	-11431.0
NCK1	-11454.0
PAK6	-11505.0
RPS6KA5	-11594.0
FYN	-11675.0
NCAM1	-11706.0
SMAD3	-11745.0
EZR	-11769.0
AGRN	-11770.0
AKT3	-11849.0
UTRN	-11895.0
DLG3	-11922.0
GATA6	-11928.0
PRKACB	-11959.0
GFI1	-11968.0
PIK3R3	-12015.0
EOMES	-12053.0
PRKCQ	-12127.0
YES1	-12142.0
RBBP7	-12155.0
KRT5	-12189.0
EVL	-12207.0
ERBB2	-12320.0
AKAP5	-12326.0
EPHA2	-12356.0
TFDP2	-12364.0

---

Golgi-to-ER retrograde transport

Golgi-to-ER retrograde transport

	470
set	Golgi-to-ER retrograde transport
setSize	111
pANOVA	1.79e-09
s.dist	0.33
p.adjustANOVA	4.53e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ARF4	9191
PLA2G4A	9180
DCTN2	9157
KDELR1	9142
ARF1	9064
RAB1A	9052
GALNT2	8843
NSF	8829
BICD2	8746
CAPZA2	8597
DCTN4	8387
COPA	8366
RAB1B	8313
KIF3C	8306
KIF5B	8239
KIF1B	8184
RAB6A	8148
CAPZA1	8135
CAPZB	8015
TMED7	7950

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ARF4	9191
PLA2G4A	9180
DCTN2	9157
KDELR1	9142
ARF1	9064
RAB1A	9052
GALNT2	8843
NSF	8829
BICD2	8746
CAPZA2	8597
DCTN4	8387
COPA	8366
RAB1B	8313
KIF3C	8306
KIF5B	8239
KIF1B	8184
RAB6A	8148
CAPZA1	8135
CAPZB	8015
TMED7	7950
COPB2	7902
ARF5	7885
RAB18	7801
KIF1C	7799
DYNC1I2	7735
ARF3	7732
KDELR2	7728
ACTR10	7605
COPG2	7594
COPG1	7509
KLC3	7377
COPB1	7321
DCTN6	7300
TMED9	7167
SURF4	7058
ACTR1A	7002
PAFAH1B2	6942
DYNC1LI1	6941
COPE	6896
GALNT1	6508
RAB6B	6053
TMED2	6052
KIF13B	5998
DCTN3	5994
DYNLL1	5952
SEC22B	5873
RAB3GAP1	5768
ARCN1	5580
KLC1	5523
KIF23	5510
PAFAH1B1	5470
KIF20A	5096
DCTN1	5078
AGPAT3	4809
STX18	4648
RAB3GAP2	4429
PAFAH1B3	4417
DYNC1LI2	4273
KIF9	4253
DYNC1I1	4187
NAPG	4139
COPZ1	4035
KIF3B	3740
ARFGAP3	3714
KIF4A	3585
RACGAP1	2848
KIF16B	2785
TMED3	2720
KIF27	2549
NAPA	1432
KIF6	1147
USE1	938
KIF11	787
KIF2C	726
CENPE	332
TMED10	323
NBAS	208
ZW10	31
KIF18B	-143
KIFC1	-249
KIF2A	-1069
KIFC2	-1642
ARFGAP1	-1942
KDELR3	-2117
KIF18A	-2742
NAPB	-2780
KIF15	-3249
DYNLL2	-3980
DCTN5	-4086
GBF1	-4290
KIF26A	-4925
ARFGAP2	-5786
KIF21B	-6702
KIF28P	-6770
BICD1	-7365
BNIP1	-7588
DYNC1H1	-7685
KIF20B	-7822
KLC4	-8376
KIFAP3	-8619
KIF5C	-8865
KIF5A	-8869
KLC2	-9059
RINT1	-10112
COPZ2	-10863
KIF26B	-11663
KIF19	-11733
KIF21A	-11837
KIF3A	-11972
PLA2G6	-12122
KIF22	-12358

---

COPI-mediated anterograde transport

COPI-mediated anterograde transport

	134
set	COPI-mediated anterograde transport
setSize	78
pANOVA	1.9e-09
s.dist	0.393
p.adjustANOVA	4.72e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ARF4	9191
DCTN2	9157
SPTB	9154
CD55	9145
KDELR1	9142
ARF1	9064
RAB1A	9052
NSF	8829
ANK1	8771
CAPZA2	8597
DCTN4	8387
COPA	8366
RAB1B	8313
CAPZA1	8135
CAPZB	8015
TMED7	7950
COPB2	7902
ARF5	7885
DYNC1I2	7735
ARF3	7732

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ARF4	9191
DCTN2	9157
SPTB	9154
CD55	9145
KDELR1	9142
ARF1	9064
RAB1A	9052
NSF	8829
ANK1	8771
CAPZA2	8597
DCTN4	8387
COPA	8366
RAB1B	8313
CAPZA1	8135
CAPZB	8015
TMED7	7950
COPB2	7902
ARF5	7885
DYNC1I2	7735
ARF3	7732
KDELR2	7728
ACTR10	7605
SPTA1	7595
COPG2	7594
COPG1	7509
COPB1	7321
DCTN6	7300
TMED9	7167
STX5	7166
ACTR1A	7002
DYNC1LI1	6941
COPE	6896
GORASP1	6606
GOLGA2	6203
TMED2	6052
DCTN3	5994
DYNLL1	5952
CD59	5859
ARCN1	5580
TMEM115	5508
YKT6	5205
DCTN1	5078
DYNC1LI2	4273
COG7	4269
DYNC1I1	4187
USO1	4154
NAPG	4139
COPZ1	4035
ARFGAP3	3714
TMED3	2720
NAPA	1432
TMED10	323
COG4	-6
GOSR1	-182
COG8	-346
BET1	-594
GOSR2	-1456
ARFGAP1	-1942
KDELR3	-2117
NAPB	-2780
COG5	-3259
SPTBN5	-3531
DYNLL2	-3980
DCTN5	-4086
GBF1	-4290
ANK3	-4919
SPTBN2	-5129
GOLGB1	-5370
COG3	-5426
ARFGAP2	-5786
COG6	-5811
BET1L	-7405
DYNC1H1	-7685
SPTBN1	-7764
COG2	-7917
COPZ2	-10863
SPTAN1	-11426
COG1	-12125

---

Autophagy

Autophagy

	97
set	Autophagy
setSize	124
pANOVA	2.12e-09
s.dist	0.311
p.adjustANOVA	5.17e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RNASE1	9467
PLIN3	9437
LAMTOR1	9411
MTMR3	9069
HBB	9054
GABARAPL2	9044
PINK1	8941
CHMP4B	8866
LAMP2	8786
CHMP2A	8780
RRAGD	8753
UBAP1	8701
LAMTOR5	8498
CHMP3	8349
ATG3	8293
PLIN2	8261
ATG7	8134
NBR1	8119
MAP1LC3B	8043
MTMR14	8032

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RNASE1	9467
PLIN3	9437
LAMTOR1	9411
MTMR3	9069
HBB	9054
GABARAPL2	9044
PINK1	8941
CHMP4B	8866
LAMP2	8786
CHMP2A	8780
RRAGD	8753
UBAP1	8701
LAMTOR5	8498
CHMP3	8349
ATG3	8293
PLIN2	8261
ATG7	8134
NBR1	8119
MAP1LC3B	8043
MTMR14	8032
VPS37C	8010
GABARAP	7904
EPAS1	7886
TSG101	7786
DYNC1I2	7735
RHEB	7669
LAMTOR3	7574
LAMTOR2	7567
MVB12A	7400
WIPI1	7277
ULK1	7125
MAP1LC3A	7094
DYNC1LI1	6941
VCP	6886
MFN2	6750
GFAP	6713
UBB	6639
BECN1	6516
VPS37A	6467
PARK7	6421
CSNK2A2	6388
RRAGA	6244
CSNK2A1	6199
ATG9A	6067
HSF1	6063
DYNLL1	5952
CHMP2B	5714
UBE2V1	5637
ATG10	5553
CHMP6	5499
PRKAG1	5476
WIPI2	5330
MVB12B	5175
RRAGC	4954
RB1CC1	4946
ATG4C	4607
LAMTOR4	4441
UBC	4439
VDAC1	4347
DYNC1LI2	4273
PEX5	4225
VPS28	4199
DYNC1I1	4187
SQSTM1	4081
CSNK2B	3969
VPS37B	3908
ATG101	3754
TOMM22	3403
WDR45	2925
SLC38A9	2807
CFTR	2416
CHMP4A	2400
TOMM6	2323
PRKAG2	2015
UBE2N	1936
PIK3C3	1619
WDR45B	1590
ATG5	1398
HSP90AA1	1326
PRKAA1	1322
PRKAB1	1302
UBA52	1121
USP30	856
ATG4A	666
ATG13	640
MLST8	376
RRAGB	-713
ATG12	-770
TSC2	-804
TOMM5	-1539
TSC1	-2118
IFT88	-2201
GABARAPL1	-2419
TOMM20	-2743
ARL13B	-3064
ATG4B	-3468
DYNLL2	-3980
PIK3R4	-4062
ATG4D	-4386
MFN1	-4966
TOMM7	-4975
EEF1A1	-5087
PGAM5	-5356
FUNDC1	-6036
MTERF3	-6856
HSP90AB1	-6863
RPS27A	-6938
DYNC1H1	-7685
TOMM40	-7967
PRKAB2	-8172
AMBRA1	-8186
HDAC6	-8337
TOMM70	-8541
CHMP7	-8802
SRC	-8820
UVRAG	-9024
MTOR	-9767
ATG9B	-9906
RPTOR	-10464
HSPA8	-10922
ATM	-11148
ATG14	-11847
ATG16L1	-11966
PCNT	-12169

---

Apoptosis

Apoptosis

	79
set	Apoptosis
setSize	168
pANOVA	2.16e-09
s.dist	0.268
p.adjustANOVA	5.17e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H1-2	9491
VIM	9394
LMNB1	9345
YWHAG	9264
CD14	9097
YWHAE	9045
TLR4	9016
APAF1	9015
PRKCD	9008
MAPK3	8953
LY96	8795
GSN	8749
BCL2L1	8700
HMGB2	8671
BMX	8664
YWHAH	8649
PSMB7	8485
TFDP1	8470
PSMD4	8402
UNC5A	8399

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H1-2	9491
VIM	9394
LMNB1	9345
YWHAG	9264
CD14	9097
YWHAE	9045
TLR4	9016
APAF1	9015
PRKCD	9008
MAPK3	8953
LY96	8795
GSN	8749
BCL2L1	8700
HMGB2	8671
BMX	8664
YWHAH	8649
PSMB7	8485
TFDP1	8470
PSMD4	8402
UNC5A	8399
TNFRSF10B	8321
PSME3	8251
PAK2	8185
PPP3R1	8175
PSMB5	8101
STAT3	8098
PSMD6	7846
DBNL	7749
CASP9	7685
PSMD9	7620
CFLAR	7610
MAPK1	7493
H1-0	7492
ROCK1	7489
PSMD2	7411
BCL2L11	7384
PSMA1	7329
PSMD1	7241
DAPK2	7237
PSMB3	7171
PSMA7	7096
PSMC1	7021
DAPK1	6924
BAD	6892
PSMB6	6813
SEPTIN4	6703
PSMF1	6659
UBB	6639
PSMC6	6635
BCAP31	6565
PSMD12	6556
STK24	6487
CTNNB1	6408
YWHAB	6385
E2F1	6343
TICAM2	6335
TICAM1	6307
PSMD11	6231
BID	6020
PSMA6	5970
PSMD7	5963
DYNLL1	5952
PSMD13	5948
BAX	5916
PSMD8	5757
ADD1	5704
FADD	5641
YWHAZ	5624
TP53BP2	5532
PSMA2	5339
APIP	4962
CARD8	4726
BIRC2	4692
PLEC	4633
PSMD3	4618
DAPK3	4514
PTK2	4462
UBC	4439
BMF	4375
SEM1	4348
NMT1	4328
TJP2	4142
PSMB2	4084
LMNA	3887
FAS	3712
CLSPN	3640
AKT1	3614
PSMD5	3426
PSMB1	3374
DFFA	3371
APC	3240
TNFSF10	3093
DNM1L	3015
OMA1	2947
UNC5B	2809
OPA1	2740
PSMD14	2611
PSMC2	2598
PSMB4	2523
KPNB1	2430
H1-4	2207
UACA	2159
PSMC3	1976
TNFRSF10A	1815
SFN	1615
PSMD10	1559
XIAP	1407
KPNA1	1296
UBA52	1121
ACIN1	862
AKT2	433
APPL1	336
CASP7	55
HMGB1	-252
BAK1	-309
TRADD	-556
PSMA4	-616
CASP3	-632
C1QBP	-822
PSMC5	-863
CYCS	-1334
DSP	-1812
OCLN	-2327
CASP6	-2831
PSMB8	-3076
DYNLL2	-3980
BCL2	-4704
TP73	-4754
CDKN2A	-5236
PSMA3	-5285
MAPT	-5437
FNTA	-5724
PSMB10	-5735
PSMA5	-6053
PSME4	-6087
TJP1	-6374
DIABLO	-6393
DFFB	-6836
RPS27A	-6938
YWHAQ	-7340
PSMA8	-7606
BBC3	-7864
SATB1	-7905
AVEN	-8133
GAS2	-8542
ARHGAP10	-8847
PSMC4	-9127
MAPK8	-9428
PSME1	-9991
PSME2	-10336
TP63	-10842
STK26	-10888
TP53	-10893
PMAIP1	-10986
RIPK1	-11074
PSMB9	-11324
CASP8	-11336
SPTAN1	-11426
CDH1	-11500
PPP1R13B	-11636
TRAF2	-11746
AKT3	-11849
PPP3CC	-12126
PRKCQ	-12127
MAGED1	-12295
GZMB	-12361
TFDP2	-12364
FASLG	-12371

---

EPH-Ephrin signaling

EPH-Ephrin signaling

	323
set	EPH-Ephrin signaling
setSize	79
pANOVA	2.31e-09
s.dist	0.389
p.adjustANOVA	5.45e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SDCBP	9311
ITSN1	9289
ARPC1B	9259
NCSTN	9186
ACTB	9011
CLTC	9000
CLTCL1	8965
ARPC1A	8894
RAC1	8793
ADAM10	8791
ARPC5	8686
AP2M1	8627
MYL6	8576
ACTG1	8562
EPHB3	8479
CLTA	8376
RHOA	8319
ARPC3	8277
PAK1	8230
CFL1	8186

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SDCBP	9311
ITSN1	9289
ARPC1B	9259
NCSTN	9186
ACTB	9011
CLTC	9000
CLTCL1	8965
ARPC1A	8894
RAC1	8793
ADAM10	8791
ARPC5	8686
AP2M1	8627
MYL6	8576
ACTG1	8562
EPHB3	8479
CLTA	8376
RHOA	8319
ARPC3	8277
PAK1	8230
CFL1	8186
PAK2	8185
LIMK2	8074
AP2S1	8026
PSEN1	7961
ACTR2	7870
ACTR3	7818
LYN	7809
MYL9	7703
CDC42	7537
ARPC4	7516
ROCK1	7489
ARPC2	7390
AP2A2	7257
MYL12A	6899
AP2A1	6832
MYH9	6685
APH1B	6280
ROCK2	6138
EFNA4	6133
CLTB	6084
PSENEN	5735
SDC2	5397
EPHB4	5203
MYL12B	5088
NCK2	4934
VAV3	4894
LIMK1	4679
PTK2	4462
EPHB2	4355
APH1A	4133
DNM1	3587
EFNA1	2933
RASA1	2106
MMP9	1690
MYH10	653
TIAM1	651
WASL	299
EPHB6	175
AP2B1	-2709
HRAS	-3382
MYH11	-3522
KALRN	-3692
VAV2	-4055
PAK3	-4184
ARHGEF7	-4583
EPHA1	-5111
EFNB2	-6182
PSEN2	-7718
EFNA3	-8004
SRC	-8820
EFNA5	-8908
GIT1	-9471
EPHB1	-10082
ARHGEF28	-10288
EFNB1	-10819
EPHA4	-11431
FYN	-11675
YES1	-12142
EPHA2	-12356

---

Amyloid fiber formation

Amyloid fiber formation

	70
set	Amyloid fiber formation
setSize	51
pANOVA	2.44e-09
s.dist	0.483
p.adjustANOVA	5.64e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SNCA	9354.0
H2BC21	9283.0
NCSTN	9186.0
APP	9177.0
FURIN	9075.0
H2BC12	9051.0
ADAM10	8791.0
GSN	8749.0
H3-3A	8661.0
SIAH2	8578.0
TGFBI	8211.0
H2BC5	8003.0
H2AC6	7934.0
H2BC11	7912.0
H2BC4	7389.0
H2BC17	7285.0
LYZ	7213.0
TSPAN14	6971.0
H3C15	6699.5
UBB	6639.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SNCA	9354.0
H2BC21	9283.0
NCSTN	9186.0
APP	9177.0
FURIN	9075.0
H2BC12	9051.0
ADAM10	8791.0
GSN	8749.0
H3-3A	8661.0
SIAH2	8578.0
TGFBI	8211.0
H2BC5	8003.0
H2AC6	7934.0
H2BC11	7912.0
H2BC4	7389.0
H2BC17	7285.0
LYZ	7213.0
TSPAN14	6971.0
H3C15	6699.5
UBB	6639.0
SORL1	6530.0
LTF	6306.0
APH1B	6280.0
TSPAN33	6170.0
H2AZ1	6036.0
ITM2B	5982.0
PSENEN	5735.0
USP9X	5464.0
H2BC9	5394.0
H2BC15	5312.0
H2AC20	4972.0
UBC	4439.0
APH1A	4133.0
GGA3	3816.0
BACE1	3609.0
MFGE8	3534.0
GGA1	2310.0
CST3	2206.0
UBA52	1121.0
TSPAN5	1028.0
NPPA	-584.0
TSPAN15	-1876.0
CALB1	-2832.0
SIAH1	-3000.0
NAT8B	-3939.0
H2BU1	-6555.0
GGA2	-6587.0
B2M	-6920.0
RPS27A	-6938.0
HSPG2	-7779.0
UBE2L6	-11293.0

---

Signaling by WNT

Signaling by WNT

	1141
set	Signaling by WNT
setSize	254
pANOVA	4.05e-09
s.dist	0.214
p.adjustANOVA	9.22e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FZD5	9513
H2AJ	9374
GNG10	9349
SNX3	9326
H2BC21	9283
WNT11	9215
KREMEN1	9149
FRAT2	9096
AGO4	9070
H2BC12	9051
CLTC	9000
PLCB3	8916
GNG5	8815
RAC1	8793
FRAT1	8712
RNF146	8696
H3-3A	8661
AP2M1	8627
TLE3	8558
ARRB2	8490

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FZD5	9513.0
H2AJ	9374.0
GNG10	9349.0
SNX3	9326.0
H2BC21	9283.0
WNT11	9215.0
KREMEN1	9149.0
FRAT2	9096.0
AGO4	9070.0
H2BC12	9051.0
CLTC	9000.0
PLCB3	8916.0
GNG5	8815.0
RAC1	8793.0
FRAT1	8712.0
RNF146	8696.0
H3-3A	8661.0
AP2M1	8627.0
TLE3	8558.0
ARRB2	8490.0
PSMB7	8485.0
PSMD4	8402.0
CLTA	8376.0
RHOA	8319.0
GNB1	8294.0
PSME3	8251.0
PPP2CA	8234.0
PPP3R1	8175.0
GNB2	8141.0
WLS	8104.0
PSMB5	8101.0
AP2S1	8026.0
H2BC5	8003.0
H2AC6	7934.0
H2BC11	7912.0
PSMD6	7846.0
CSNK1A1	7766.0
PPP2CB	7712.0
PSMD9	7620.0
CTNNBIP1	7569.0
KLHL12	7429.0
PSMD2	7411.0
H2BC4	7389.0
GNB4	7336.0
PSMA1	7329.0
H2BC17	7285.0
AP2A2	7257.0
PSMD1	7241.0
PSMB3	7171.0
PRKCB	7097.0
PSMA7	7096.0
PSMC1	7021.0
PPP3CB	7005.0
TMED5	6984.0
PRKG1	6901.0
TLE4	6854.0
AP2A1	6832.0
CUL3	6821.0
PSMB6	6813.0
PPP2R5B	6774.0
H3C15	6699.5
GNAT2	6683.0
VPS35	6668.0
PSMF1	6659.0
UBB	6639.0
PSMC6	6635.0
GSK3B	6634.0
VPS26A	6632.0
PSMD12	6556.0
GNG11	6495.0
FZD2	6462.0
PIP5K1B	6450.0
USP8	6418.0
CTNNB1	6408.0
CSNK2A2	6388.0
PSMD11	6231.0
PPP3CA	6217.0
CSNK2A1	6199.0
EP300	6129.0
CLTB	6084.0
H2AZ1	6036.0
ASH2L	6001.0
PSMA6	5970.0
PSMD7	5963.0
PSMD13	5948.0
PPP2R5A	5897.0
ITPR2	5842.0
PSMD8	5757.0
SOX6	5665.0
DVL3	5656.0
AGO1	5654.0
YWHAZ	5624.0
PFN1	5459.0
H2BC9	5394.0
PSMA2	5339.0
H2BC15	5312.0
RAC2	5163.0
CDC73	5020.0
H2AC20	4972.0
WNT6	4864.0
SOX4	4850.0
SMARCA4	4733.0
PLCB2	4665.0
PSMD3	4618.0
PPP2R1A	4589.0
FZD1	4492.0
UBC	4439.0
SEM1	4348.0
GNG8	4296.0
LRP5	4289.0
SKP1	4287.0
PSMB2	4084.0
CTBP2	4080.0
CSNK2B	3969.0
RBX1	3934.0
ZRANB1	3730.0
KRAS	3702.0
AKT1	3614.0
DAAM1	3466.0
PSMD5	3426.0
CREBBP	3423.0
NLK	3405.0
PSMB1	3374.0
APC	3240.0
KMT2D	3203.0
VPS29	3151.0
AGO2	2995.0
LGR4	2883.0
PSMD14	2611.0
PSMC2	2598.0
PSMB4	2523.0
PPP2R5D	2421.0
MAP3K7	2395.0
MYC	2304.0
PRICKLE1	2283.0
WNT9B	1992.0
PSMC3	1976.0
CAV1	1969.0
PSMD10	1559.0
XIAP	1407.0
TERT	1341.0
KAT5	1314.0
DACT1	1252.0
PLCB1	1197.0
PRKCA	1132.0
UBA52	1121.0
RBBP5	1037.0
GNG3	890.0
CSNK1G2	887.0
CHD8	604.0
HDAC1	587.0
LRP6	577.0
GNB5	512.0
AKT2	433.0
KREMEN2	316.0
TCF7L1	275.0
LEO1	39.0
DVL1	0.0
WNT5B	-61.0
PARD6A	-239.0
PPP2R1B	-241.0
TNKS2	-499.0
PSMA4	-616.0
PPP2R5E	-680.0
PSMC5	-863.0
USP34	-944.0
AGO3	-1011.0
XPO1	-1185.0
PDE6G	-1189.0
BCL9	-1190.0
H2AZ2	-1209.0
ZNRF3	-1963.0
CALM1	-2081.0
GNG4	-2154.0
PDE6A	-2204.0
ROR1	-2376.0
GNB3	-2397.0
SMURF1	-2591.0
SOX7	-2675.0
AP2B1	-2709.0
WNT8B	-2841.0
SCRIB	-2849.0
PSMB8	-3076.0
RAC3	-3262.0
TCF4	-3836.0
WNT2B	-3938.0
WNT9A	-4397.0
WNT4	-4485.0
TNRC6B	-4518.0
WNT3	-4684.0
WNT16	-4921.0
BTRC	-4924.0
GNG7	-5198.0
PSMA3	-5285.0
TNRC6A	-5613.0
PSMB10	-5735.0
PSMA5	-6053.0
PSME4	-6087.0
TCF7L2	-6185.0
CTBP1	-6456.0
FZD7	-6508.0
FZD6	-6525.0
H2BU1	-6555.0
TRRAP	-6722.0
RPS27A	-6938.0
TLE1	-6942.0
FZD8	-7138.0
FZD3	-7186.0
TLE2	-7449.0
PSMA8	-7606.0
ITPR1	-7629.0
GNG2	-7795.0
WNT7A	-7966.0
LEF1	-8076.0
CXXC4	-8078.0
AXIN2	-8154.0
PRKG2	-8477.0
MEN1	-8538.0
RUVBL1	-8612.0
TNKS	-8738.0
WNT1	-9014.0
PSMC4	-9127.0
NFATC1	-9147.0
RYK	-9346.0
WNT10A	-9848.0
WNT10B	-9917.0
GNAO1	-9936.0
PSME1	-9991.0
PORCN	-10074.0
CBY1	-10077.0
TCF7	-10173.0
AXIN1	-10285.0
CSNK1E	-10298.0
ITPR3	-10308.0
PSME2	-10336.0
SMURF2	-10340.0
DVL2	-11152.0
PPP2R5C	-11265.0
SOX13	-11280.0
AMER1	-11301.0
PSMB9	-11324.0
PYGO2	-11326.0
CUL1	-11330.0
PDE6B	-11387.0
FZD4	-11650.0
TNRC6C	-11828.0
TLE5	-11957.0
BCL9L	-11981.0
MOV10	-11991.0
CCDC88C	-12041.0
GNGT2	-12086.0
RNF43	-12121.0
LGR6	-12286.0
RUNX3	-12352.0

---

RHO GTPases activate PKNs

RHO GTPases activate PKNs

	895
set	RHO GTPases activate PKNs
setSize	48
pANOVA	6.95e-09
s.dist	0.483
p.adjustANOVA	1.56e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AJ	9374.0
H2BC21	9283.0
YWHAG	9264.0
H2BC12	9051.0
YWHAE	9045.0
RAC1	8793.0
H3-3A	8661.0
YWHAH	8649.0
MYL6	8576.0
RHOA	8319.0
PAK1	8230.0
H2BC5	8003.0
H2AC6	7934.0
H2BC11	7912.0
MYL9	7703.0
H2BC4	7389.0
H2BC17	7285.0
PPP1CB	7064.0
PPP1R14A	6839.0
H3C15	6699.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AJ	9374.0
H2BC21	9283.0
YWHAG	9264.0
H2BC12	9051.0
YWHAE	9045.0
RAC1	8793.0
H3-3A	8661.0
YWHAH	8649.0
MYL6	8576.0
RHOA	8319.0
PAK1	8230.0
H2BC5	8003.0
H2AC6	7934.0
H2BC11	7912.0
MYL9	7703.0
H2BC4	7389.0
H2BC17	7285.0
PPP1CB	7064.0
PPP1R14A	6839.0
H3C15	6699.5
MYH9	6685.0
YWHAB	6385.0
PDPK1	6136.0
PPP1R12A	6050.0
H2AZ1	6036.0
YWHAZ	5624.0
H2BC9	5394.0
H2BC15	5312.0
MYL12B	5088.0
H2AC20	4972.0
CDC25C	4969.0
AR	4840.0
KLK2	3029.0
PPP1R12B	1775.0
SFN	1615.0
RHOB	1254.0
NCOA2	1092.0
MYH10	653.0
PKN2	98.0
H2AZ2	-1209.0
PKN1	-2208.0
MYH11	-3522.0
PKN3	-3793.0
H2BU1	-6555.0
YWHAQ	-7340.0
KDM1A	-9430.0
KDM4C	-10749.0
RHOC	-11360.0

---

MyD88-independent TLR4 cascade

MyD88-independent TLR4 cascade

	689
set	MyD88-independent TLR4 cascade
setSize	96
pANOVA	7.99e-09
s.dist	0.341
p.adjustANOVA	1.73e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
DUSP3	9280
UBE2D1	9187
APP	9177
MAPK14	9104
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
MAP2K6	8887
LY96	8795
MAP2K3	8748
UBE2D3	8640
NOD2	8442
MAPKAPK3	8382
PPP2CA	8234
MEF2A	8009
CHUK	7966
PPP2CB	7712

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
DUSP3	9280
UBE2D1	9187
APP	9177
MAPK14	9104
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
MAP2K6	8887
LY96	8795
MAP2K3	8748
UBE2D3	8640
NOD2	8442
MAPKAPK3	8382
PPP2CA	8234
MEF2A	8009
CHUK	7966
PPP2CB	7712
RPS6KA1	7695
TANK	7502
MAPK1	7493
TAB2	6964
MAP2K4	6866
NFKBIA	6807
UBB	6639
TICAM2	6335
TICAM1	6307
NFKB1	6277
FBXW11	6196
MAP3K8	6160
IRAK1	6131
ATF1	5706
TAB1	5681
FADD	5641
UBE2V1	5637
TNIP2	5552
FOS	5460
IKBKG	5377
PTPN11	5314
IKBKE	4715
BIRC2	4692
UBE2D2	4657
PPP2R1A	4589
UBC	4439
DUSP6	4357
MAPK10	4325
SKP1	4287
RIPK3	4217
MAPKAPK2	4054
MAPK11	3826
JUN	3722
TBK1	3229
TAB3	3160
RPS6KA2	3087
RPS6KA3	2973
PPP2R5D	2421
MAP3K7	2395
ATF2	2085
UBE2N	1936
MAP2K7	1654
AGER	1294
VRK3	1281
UBA52	1121
ELK1	1040
RIPK2	1025
NKIRAS1	375
NFKBIB	-152
TRAF6	-229
PPP2R1B	-241
HMGB1	-252
MEF2C	-293
NFKB2	-1165
MAPK7	-1337
CREB1	-1378
RELA	-1803
DUSP7	-3211
BTRC	-4924
IKBKB	-5386
S100B	-5457
TRAF3	-5576
DUSP4	-6287
RPS27A	-6938
MAPK9	-7068
IRF3	-8517
IRF7	-8657
MAPK8	-9428
IRAK2	-9548
RIPK1	-11074
BIRC3	-11125
CUL1	-11330
CASP8	-11336
RPS6KA5	-11594
SARM1	-12134
NOD1	-12263

---

TRIF(TICAM1)-mediated TLR4 signaling

TRIF(TICAM1)-mediated TLR4 signaling

	1217
set	TRIF(TICAM1)-mediated TLR4 signaling
setSize	96
pANOVA	7.99e-09
s.dist	0.341
p.adjustANOVA	1.73e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
DUSP3	9280
UBE2D1	9187
APP	9177
MAPK14	9104
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
MAP2K6	8887
LY96	8795
MAP2K3	8748
UBE2D3	8640
NOD2	8442
MAPKAPK3	8382
PPP2CA	8234
MEF2A	8009
CHUK	7966
PPP2CB	7712

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
DUSP3	9280
UBE2D1	9187
APP	9177
MAPK14	9104
CD14	9097
MAP2K1	9063
TLR4	9016
MAPK3	8953
MAP2K6	8887
LY96	8795
MAP2K3	8748
UBE2D3	8640
NOD2	8442
MAPKAPK3	8382
PPP2CA	8234
MEF2A	8009
CHUK	7966
PPP2CB	7712
RPS6KA1	7695
TANK	7502
MAPK1	7493
TAB2	6964
MAP2K4	6866
NFKBIA	6807
UBB	6639
TICAM2	6335
TICAM1	6307
NFKB1	6277
FBXW11	6196
MAP3K8	6160
IRAK1	6131
ATF1	5706
TAB1	5681
FADD	5641
UBE2V1	5637
TNIP2	5552
FOS	5460
IKBKG	5377
PTPN11	5314
IKBKE	4715
BIRC2	4692
UBE2D2	4657
PPP2R1A	4589
UBC	4439
DUSP6	4357
MAPK10	4325
SKP1	4287
RIPK3	4217
MAPKAPK2	4054
MAPK11	3826
JUN	3722
TBK1	3229
TAB3	3160
RPS6KA2	3087
RPS6KA3	2973
PPP2R5D	2421
MAP3K7	2395
ATF2	2085
UBE2N	1936
MAP2K7	1654
AGER	1294
VRK3	1281
UBA52	1121
ELK1	1040
RIPK2	1025
NKIRAS1	375
NFKBIB	-152
TRAF6	-229
PPP2R1B	-241
HMGB1	-252
MEF2C	-293
NFKB2	-1165
MAPK7	-1337
CREB1	-1378
RELA	-1803
DUSP7	-3211
BTRC	-4924
IKBKB	-5386
S100B	-5457
TRAF3	-5576
DUSP4	-6287
RPS27A	-6938
MAPK9	-7068
IRF3	-8517
IRF7	-8657
MAPK8	-9428
IRAK2	-9548
RIPK1	-11074
BIRC3	-11125
CUL1	-11330
CASP8	-11336
RPS6KA5	-11594
SARM1	-12134
NOD1	-12263

---

ROS and RNS production in phagocytes

ROS and RNS production in phagocytes

	926
set	ROS and RNS production in phagocytes
setSize	31
pANOVA	8.23e-09
s.dist	0.598
p.adjustANOVA	1.76e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ATP6V0A1	9423
ATP6V1A	9302
NCF4	9268
ATP6V0D1	9245
NCF2	9190
SLC11A1	9169
ATP6V0C	9127
ATP6V1B2	9057
ATP6V1D	9047
CYBB	9031
ATP6V0B	8598
ATP6V0E1	8596
ATP6V1C1	8539
ATP6V1H	8064
ATP6V1E1	8035
MPO	7437
NCF1	7334
TCIRG1	7188
CYBA	6922
LPO	6502

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ATP6V0A1	9423
ATP6V1A	9302
NCF4	9268
ATP6V0D1	9245
NCF2	9190
SLC11A1	9169
ATP6V0C	9127
ATP6V1B2	9057
ATP6V1D	9047
CYBB	9031
ATP6V0B	8598
ATP6V0E1	8596
ATP6V1C1	8539
ATP6V1H	8064
ATP6V1E1	8035
MPO	7437
NCF1	7334
TCIRG1	7188
CYBA	6922
LPO	6502
ATP6V1F	5878
ATP6V1E2	5730
RAC2	5163
HVCN1	4912
ATP6V1G1	3931
NOS1	1365
NOS3	-2059
ATP6V1C2	-2219
ATP6V1G2	-9515
ATP6V0E2	-11555
ATP6V0A2	-12211

---

Infectious disease

Infectious disease

	526
set	Infectious disease
setSize	777
pANOVA	1.03e-08
s.dist	0.121
p.adjustANOVA	2.18e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
WASF1	9520
HRH2	9466
CD163	9462
PRKACA	9429
GGT1	9426
ADM	9378
GNG10	9349
GPR27	9340
FCGR1A	9323
GRB2	9304
IMPDH1	9294
AP1S1	9286
H2BC21	9283
IFNGR1	9273
IL10	9272
CYFIP1	9265
ARPC1B	9259
IFNGR2	9238
PHF21A	9216
ST6GALNAC3	9134

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
WASF1	9520.0
HRH2	9466.0
CD163	9462.0
PRKACA	9429.0
GGT1	9426.0
ADM	9378.0
GNG10	9349.0
GPR27	9340.0
FCGR1A	9323.0
GRB2	9304.0
IMPDH1	9294.0
AP1S1	9286.0
H2BC21	9283.0
IFNGR1	9273.0
IL10	9272.0
CYFIP1	9265.0
ARPC1B	9259.0
IFNGR2	9238.0
PHF21A	9216.0
ST6GALNAC3	9134.0
GPR84	9133.0
GUCY2C	9122.0
MAPK14	9104.0
TLR2	9103.0
SYK	9076.0
FURIN	9075.0
RCOR1	9073.0
ARF1	9064.0
MAP2K1	9063.0
FKBP1A	9056.0
H2BC12	9051.0
ACTB	9011.0
CLTC	9000.0
ADCY3	8984.0
HCK	8976.0
MAPK3	8953.0
MYO10	8918.0
IL1R1	8917.0
CRK	8906.0
NLRP3	8901.0
ARPC1A	8894.0
ENO1	8890.0
MAP2K6	8887.0
CHMP4B	8866.0
FCGR2A	8845.0
NUP58	8820.0
CEBPD	8816.0
GNG5	8815.0
RAC1	8793.0
CHMP2A	8780.0
MAP2K3	8748.0
RAB7A	8742.0
AP1B1	8730.0
RB1	8707.0
EDEM2	8704.0
UBAP1	8701.0
ARPC5	8686.0
MGAT4B	8675.0
PGK1	8672.0
ST3GAL2	8669.0
PYCARD	8638.0
AP2M1	8627.0
PRKAR1A	8607.0
MEFV	8605.0
ACTG1	8562.0
WAS	8560.0
PSMB7	8485.0
FGR	8478.0
ADORA2B	8437.0
DNAJC3	8435.0
IFNAR1	8413.0
PSMD4	8402.0
CLTA	8376.0
WASF2	8369.0
ENTPD1	8360.0
CHMP3	8349.0
SAP30	8303.0
GNB1	8294.0
TXN	8285.0
ARPC3	8277.0
COMT	8273.0
PSME3	8251.0
JAK3	8219.0
TXNRD1	8192.0
PAK2	8185.0
TRIM27	8142.0
GNB2	8141.0
IL6R	8132.0
ADAM17	8110.0
PSMB5	8101.0
GNAI2	8075.0
HSPA1A	8071.0
ATP6V1H	8064.0
MAP1LC3B	8043.0
AP2S1	8026.0
RPN1	8024.0
C3AR1	8012.0
VPS37C	8010.0
H2BC5	8003.0
NCOR2	7985.0
TAF12	7977.0
GNAI3	7953.0
H2AC6	7934.0
NUP214	7921.0
PRKAR1B	7918.0
H2BC11	7912.0
GNAS	7909.0
VAV1	7896.0
TBL1X	7887.0
NEDD4L	7875.0
ACTR2	7870.0
PSMD6	7846.0
PSTPIP1	7841.0
ACTR3	7818.0
LYN	7809.0
TSG101	7786.0
GSK3A	7760.0
DYNC1I2	7735.0
DOCK2	7725.0
NCKAP1L	7673.0
VPS25	7638.0
P2RX4	7630.0
SH3GL1	7625.0
PSMD9	7620.0
POLR2E	7563.0
H2BC18	7547.0
CDC42	7537.0
HNRNPK	7522.0
ELOC	7519.0
ARPC4	7516.0
H2AC11	7513.0
MAPK1	7493.0
ROCK1	7489.0
ELOB	7482.0
CBL	7480.0
VEGFA	7467.0
NCKAP1	7462.0
PSMD2	7411.0
MVB12A	7400.0
FXYD6	7391.0
ARPC2	7390.0
H2BC4	7389.0
IL18	7381.0
GNB4	7336.0
ANTXR2	7331.0
PSMA1	7329.0
DOCK1	7314.0
ELOA	7312.0
H2BC17	7285.0
AP2A2	7257.0
PSMD1	7241.0
TAF13	7217.0
BTK	7206.0
RXFP2	7189.0
RPL26L1	7176.0
PSMB3	7171.0
RPN2	7140.0
TAF10	7110.0
RAB5A	7103.0
PSMA7	7096.0
TYK2	7087.0
ABI1	7082.0
GTF2A2	7066.0
BRK1	7032.0
PSMC1	7021.0
DYNC1LI1	6941.0
DDOST	6931.0
CYBA	6922.0
SUMO1	6889.0
VCP	6886.0
MAP2K4	6866.0
AP2A1	6832.0
PSMB6	6813.0
WASF3	6808.0
MAP2K2	6794.0
XRCC4	6758.0
ST6GALNAC2	6746.0
PRKAR2B	6741.0
AP1M1	6711.0
H3C15	6699.5
MYO5A	6693.0
MYH9	6685.0
POLR2J	6671.0
IFNAR2	6665.0
PSMF1	6659.0
UBB	6639.0
PSMC6	6635.0
GSK3B	6634.0
INSL3	6594.0
PSMD12	6556.0
PDCD6IP	6528.0
BECN1	6516.0
GALNT1	6508.0
GNG11	6495.0
VPS37A	6467.0
AHCYL1	6456.0
MYO9B	6424.0
CTNNB1	6408.0
ATP1B2	6378.0
CALR	6340.0
LTF	6306.0
NFKB1	6277.0
SLC25A6	6264.0
ELMO1	6258.0
MGAT1	6257.0
PSMD11	6231.0
VTA1	6185.0
CTDP1	6180.0
SH3KBP1	6173.0
PRKAR2A	6166.0
STAM2	6159.0
ROCK2	6138.0
RLN3	6033.0
SNF8	5973.0
PSMA6	5970.0
PSMD7	5963.0
DYNLL1	5952.0
PSMD13	5948.0
CD9	5940.0
DAD1	5895.0
BRD4	5892.0
NCOR1	5887.0
ADM2	5881.0
ITPR2	5842.0
ST3GAL4	5781.0
GTF2E2	5767.0
PSMD8	5757.0
CHMP1A	5756.0
SEC13	5748.0
CHMP2B	5714.0
WIPF2	5713.0
DVL3	5656.0
CANX	5528.0
CHMP6	5499.0
HDAC2	5482.0
BRMS1	5456.0
GTF2F2	5434.0
RPS9	5421.0
H2BC9	5394.0
XRCC5	5384.0
PSMA2	5339.0
LIG4	5316.0
H2BC15	5312.0
POLR2L	5305.0
ADCY4	5270.0
CALCRL	5232.0
PRKCSH	5220.0
VPS4B	5212.0
CDK7	5211.0
SAP30L	5199.0
CORO1A	5178.0
MVB12B	5175.0
GRSF1	5169.0
RAE1	5164.0
TGFB1	5153.0
CTSG	5115.0
SYT1	5056.0
HBEGF	5013.0
ELL	5009.0
PLCG2	5006.0
SAP18	5004.0
H2AC20	4972.0
KPNA4	4957.0
GTF2F1	4951.0
CHMP5	4943.0
VAV3	4894.0
HMG20B	4839.0
IL1B	4807.0
CBX1	4751.0
HDAC3	4673.0
PSMD3	4618.0
POLR2F	4604.0
TBL1XR1	4556.0
SUDS3	4526.0
NUP50	4521.0
HGS	4513.0
RPL3L	4503.0
PTK2	4462.0
UBC	4439.0
ELMO2	4397.0
PARP4	4362.0
SEM1	4348.0
NMT1	4328.0
GNG8	4296.0
SKP1	4287.0
DYNC1LI2	4273.0
CTSL	4231.0
CASP1	4224.0
VPS28	4199.0
RHBDF2	4197.0
DYNC1I1	4187.0
EPS15	4138.0
PTGES3	4125.0
STT3A	4095.0
PSMB2	4084.0
PDZD3	4005.0
AP1G1	3987.0
RBX1	3934.0
VPS37B	3908.0
GTF2H5	3874.0
NELFE	3860.0
ARID4A	3763.0
JUN	3722.0
VHL	3674.0
ERCC2	3547.0
GTF2B	3515.0
POLR2G	3508.0
P2RX7	3475.0
PSMD5	3426.0
PSMB1	3374.0
GNAI1	3329.0
MYO1C	3310.0
ADORA2A	3293.0
TBK1	3229.0
MRC1	3109.0
NUP98	3101.0
RNGTT	3088.0
GATAD2A	3075.0
NUP37	3074.0
GTF2H2	2984.0
GNAZ	2909.0
SUPT4H1	2890.0
CCNK	2877.0
POMC	2855.0
RAMP3	2854.0
ATP1A1	2813.0
GTF2A1	2713.0
JAK2	2691.0
MAGT1	2613.0
PSMD14	2611.0
PSMC2	2598.0
PSMB4	2523.0
KPNB1	2430.0
CHMP4A	2400.0
GTF2E1	2287.0
SFPQ	2253.0
TAF7	2139.0
RPS27L	2061.0
TSHR	2051.0
PSMC3	1976.0
AP1M2	1832.0
RCC1	1766.0
IRS1	1741.0
MAP2K7	1654.0
MGAT2	1633.0
PIK3C3	1619.0
POLR2C	1616.0
PSMD10	1559.0
SUGT1	1544.0
PTGER2	1463.0
HSP90AA1	1326.0
KPNA1	1296.0
STAM	1285.0
TAF9	1250.0
UBA52	1121.0
ELK1	1040.0
KPNA3	923.0
ATP1A4	922.0
GNG3	890.0
REST	865.0
CUL5	834.0
FKBP4	832.0
SLC25A5	826.0
VPS4A	784.0
CCNH	774.0
NUP62	769.0
HDAC1	587.0
WIPF1	569.0
GNB5	512.0
NR3C1	511.0
ST3GAL3	505.0
ZCRB1	487.0
SYT2	461.0
RPS4Y1	424.0
POLR2I	396.0
NELFB	374.0
IGHV1-2	360.0
NCKIPSD	328.0
EEF2	306.0
WASL	299.0
AVPR2	291.0
IGHV2-5	230.0
ABL1	226.0
ADCY9	123.0
HMGA1	117.0
IGHV3-53	103.0
RPL36AL	32.0
RPLP1	19.0
DVL1	0.0
ARID4B	-27.0
CXCR4	-45.0
ITGB1	-94.0
BAIAP2	-215.0
RPS24	-263.0
FAU	-362.0
IGHV3-7	-441.0
PABPN1	-526.0
MBD3	-528.0
PSMA4	-616.0
IGHV1-46	-618.0
TLR7	-625.0
ST6GALNAC4	-629.0
IGHV3-48	-668.0
GGT5	-695.0
GPR83	-743.0
UBE2I	-764.0
IGKV3-11	-781.0
RANBP2	-820.0
PSMC5	-863.0
GPS2	-889.0
TCEA1	-943.0
RPL15	-963.0
GANAB	-986.0
IGKV1-39	-989.0
RPLP0	-1000.0
IGLV7-46	-1016.0
NFKB2	-1165.0
IGKV1-5	-1184.0
XPO1	-1185.0
RPL8	-1187.0
IGLV2-8	-1294.0
IGKV5-2	-1298.0
IGHV3-23	-1317.0
ATP1B3	-1347.0
MAN2A1	-1349.0
CREB1	-1378.0
RPS26	-1430.0
IGHV3-13	-1443.0
RPL28	-1462.0
IGLV2-18	-1524.0
IGKV1-16	-1528.0
IGLV4-69	-1559.0
IGKV1D-39	-1574.0
ADCY6	-1608.0
RPL22L1	-1619.0
TAF4	-1698.0
RPS13	-1749.0
GATAD2B	-1759.0
POLR2K	-1783.0
RELA	-1803.0
IGHV1-69	-1822.0
TAF3	-1850.0
SV2B	-1857.0
RBBP4	-1870.0
RPL9	-1872.0
IGLV10-54	-1884.0
RPL7	-1955.0
IGLV1-36	-2030.0
IGKV2-30	-2045.0
CALM1	-2081.0
RPS8	-2083.0
IGLV7-43	-2089.0
VPS33B	-2091.0
MGAT4C	-2109.0
IGLV3-19	-2111.0
IGHV3-11	-2134.0
GNG4	-2154.0
GTF2H3	-2235.0
AP1S2	-2261.0
IGKV3-15	-2297.0
GNB3	-2397.0
SUZ12	-2409.0
IGKV1-33	-2424.0
HTR7	-2438.0
IGHV3-30	-2484.0
POLR2B	-2523.0
IGKV4-1	-2532.0
HLA-A	-2573.0
TAF9B	-2599.0
DPEP2	-2705.0
AP2B1	-2709.0
PLK2	-2748.0
RPL27	-2855.0
IGKV1-17	-2871.0
IGLV2-23	-2878.0
IGLV6-57	-2885.0
IGHV4-59	-2892.0
DPEP3	-2894.0
ADCY2	-2896.0
IGLV2-11	-2905.0
GTF2H1	-2913.0
GTF2H4	-2916.0
TAF11	-2938.0
POLR2H	-2942.0
STX1B	-2952.0
SV2C	-2979.0
IGHV3-33	-2988.0
MTA1	-3005.0
RPL39	-3006.0
IGHV4-34	-3016.0
NUP85	-3049.0
MOGS	-3051.0
MGAT5	-3072.0
PSMB8	-3076.0
IGKV3-20	-3085.0
POLR2A	-3092.0
IGHV2-70	-3138.0
IGLV1-44	-3258.0
ADCY7	-3286.0
RPL23	-3314.0
RPL6	-3354.0
RPL13	-3431.0
IGHG3	-3481.0
RPL4	-3582.0
RPL29	-3611.0
RPL7A	-3665.0
RPS15	-3673.0
NELFA	-3886.0
IGKV3D-20	-3894.0
CDK9	-3927.0
RPL37A	-3946.0
DYNLL2	-3980.0
POLR2D	-4024.0
STX1A	-4052.0
VAV2	-4055.0
PIK3R4	-4062.0
RPS21	-4079.0
IGLV3-1	-4159.0
PARP9	-4400.0
HTR6	-4426.0
IGKC	-4428.0
XRCC6	-4471.0
RPS2	-4499.0
TAF5	-4514.0
CHD4	-4515.0
RPL31	-4541.0
IGHV4-39	-4582.0
RPS16	-4669.0
RPS3A	-4694.0
RPS28	-4713.0
RPL5	-4728.0
IGLV3-21	-4735.0
RPL22	-4740.0
BANF1	-4752.0
IGLV1-40	-4788.0
MAN1B1	-4871.0
BTRC	-4924.0
IGLV3-25	-4933.0
IGLV1-51	-4956.0
PARP6	-4959.0
RPS7	-4968.0
TRIM28	-5056.0
RPL18	-5080.0
CRHR2	-5119.0
GNG7	-5198.0
CCNT2	-5205.0
IGLC7	-5281.0
PSMA3	-5285.0
RPL36	-5287.0
CD4	-5406.0
IGLV8-61	-5427.0
FXYD1	-5429.0
RPL17	-5431.0
IGKV1-12	-5446.0
RPS14	-5463.0
NOXA1	-5464.0
IGLC3	-5477.0
IGLC2	-5510.0
AP1S3	-5522.0
NUP42	-5564.0
IGKV2D-28	-5634.0
MGAT4A	-5680.0
RPS5	-5691.0
PSMB10	-5735.0
RPS15A	-5742.0
FXYD2	-5748.0
RPS10	-5793.0
RPL24	-5799.0
IGKV2-28	-5808.0
RPL38	-5840.0
NCBP1	-5853.0
IGLV5-45	-5869.0
IGLV3-27	-5874.0
RPS3	-5914.0
TAF2	-5945.0
NT5E	-5964.0
RPS12	-5987.0
TLR9	-5999.0
RPL35A	-6015.0
IGLV1-47	-6018.0
DUT	-6046.0
PSMA5	-6053.0
SEH1L	-6069.0
RPL18A	-6070.0
PSME4	-6087.0
VIPR1	-6156.0
IGLC1	-6157.0
RPS6	-6160.0
ENTPD5	-6179.0
CRBN	-6190.0
IGHG1	-6201.0
RPS17	-6247.0
RPL27A	-6257.0
RPL11	-6261.0
NELFCD	-6277.0
RPL19	-6281.0
RPS4X	-6285.0
RPS23	-6292.0
NUP153	-6321.0
RPSA	-6323.0
RPS25	-6365.0
RPL37	-6375.0
TAF15	-6454.0
RPL21	-6458.0
FZD7	-6508.0
RPL10	-6534.0
H2BU1	-6555.0
RPL26	-6612.0
GPR15	-6636.0
DUSP16	-6655.0
RPL10A	-6686.0
RPL32	-6709.0
RPL14	-6710.0
SUPT5H	-6716.0
PPIA	-6766.0
RAN	-6791.0
PDCD1	-6792.0
RPL34	-6802.0
VPS36	-6848.0
HSP90AB1	-6863.0
RPL41	-6866.0
KPNA2	-6910.0
IGHG4	-6911.0
B2M	-6920.0
RPS27A	-6938.0
TUBB	-6956.0
RPS19	-6965.0
RPL30	-7020.0
TPR	-7028.0
RPL12	-7053.0
RPLP2	-7087.0
GPBAR1	-7132.0
POM121C	-7188.0
FXYD7	-7230.0
RPS11	-7243.0
IGHG2	-7250.0
MTA2	-7317.0
TAF6	-7352.0
IGLV3-12	-7358.0
RPL36A	-7376.0
ST3GAL1	-7442.0
PSMA8	-7606.0
ITPR1	-7629.0
ADRB1	-7674.0
CYSLTR1	-7675.0
DYNC1H1	-7685.0
SIGMAR1	-7732.0
RPS18	-7744.0
NUP133	-7762.0
ERCC3	-7783.0
GNG2	-7795.0
RPS29	-7940.0
RAMP1	-8039.0
TAF4B	-8069.0
RPL35	-8092.0
CD8B	-8188.0
RPL13A	-8212.0
ADCY5	-8235.0
POM121	-8299.0
IGLV2-14	-8345.0
AAAS	-8389.0
PARP10	-8400.0
CTNND1	-8403.0
PARP8	-8409.0
TAF1	-8476.0
NUP54	-8479.0
PACS1	-8486.0
RPL3	-8561.0
CBLL1	-8620.0
VAMP1	-8625.0
RLN2	-8636.0
MNAT1	-8687.0
PML	-8693.0
CHMP7	-8802.0
RPL39L	-8805.0
SRC	-8820.0
CCR5	-8861.0
RPS20	-8886.0
CYSLTR2	-8970.0
FXYD3	-8981.0
UVRAG	-9024.0
EIF2AK2	-9116.0
ATP1B1	-9118.0
PTGIR	-9126.0
PSMC4	-9127.0
TBP	-9167.0
S1PR1	-9211.0
EED	-9348.0
CPSF4	-9416.0
MAPK8	-9428.0
KDM1A	-9430.0
MTA3	-9433.0
CCNT1	-9469.0
NUP43	-9517.0
NPM1	-9532.0
NCBP2	-9558.0
RPL23A	-9567.0
TXNIP	-9600.0
RANBP1	-9657.0
CHD3	-9737.0
EZH2	-9741.0
PSIP1	-9743.0
FUT8	-9755.0
RPS27	-9756.0
DDX5	-9843.0
IMPDH2	-9916.0
GPR150	-9942.0
PSME1	-9991.0
CD28	-10202.0
NUP155	-10233.0
ITPR3	-10308.0
PSME2	-10336.0
CYFIP2	-10367.0
NUP107	-10421.0
PRKX	-10428.0
NUP160	-10557.0
DAXX	-10575.0
IPO5	-10591.0
FEN1	-10593.0
NUP35	-10611.0
STAT2	-10637.0
GPR25	-10677.0
NUP210	-10726.0
SV2A	-10890.0
P2RY11	-10907.0
ABI2	-10915.0
JAK1	-10955.0
ITGA4	-11043.0
LIG1	-11053.0
RIPK1	-11074.0
RNMT	-11086.0
PLCG1	-11120.0
DVL2	-11152.0
SSRP1	-11162.0
MC1R	-11184.0
NUP205	-11321.0
PSMB9	-11324.0
SUPT16H	-11359.0
NUP88	-11397.0
H2AW	-11403.0
DBP	-11441.0
NCK1	-11454.0
CDH1	-11500.0
CD3G	-11526.0
ATP1A3	-11543.0
NUP93	-11620.0
NUP188	-11624.0
FYN	-11675.0
GPR20	-11696.0
PTGER4	-11697.0
RANGAP1	-11722.0
PARP1	-11764.0
VAMP2	-11779.0
PARP16	-11830.0
LCK	-11838.0
SLC25A4	-11858.0
PARP14	-11869.0
SCT	-11886.0
ADRB2	-11892.0
KPNA5	-11893.0
RNF213	-11905.0
PRKACB	-11959.0
APOBEC3G	-11967.0
FCGR3A	-12005.0
PTGDR	-12021.0
ISG15	-12032.0
NMT2	-12035.0
ST6GAL1	-12052.0
GNGT2	-12086.0
GIPR	-12100.0
YES1	-12142.0
VIPR2	-12153.0
RBBP7	-12155.0
NDC1	-12173.0
C3	-12262.0
ZBP1	-12325.0
CD247	-12345.0

---

Generic Transcription Pathway

Generic Transcription Pathway

	447
set	Generic Transcription Pathway
setSize	1085
pANOVA	1.09e-08
s.dist	-0.103
p.adjustANOVA	2.25e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FASLG	-12371
TFDP2	-12364
RUNX3	-12352
ERBB2	-12320
NFATC2	-12294
ZNF599	-12232
PTPN4	-12220
RAD1	-12206
GATA3	-12191
ZNF287	-12168
ZNF3	-12165
RBBP7	-12155
YES1	-12142
PRKCQ	-12127
AUTS2	-12089
ZNF530	-12068
MDC1	-12059
WRN	-12047
TP53RK	-12040
ZNF74	-12012

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FASLG	-12371.0
TFDP2	-12364.0
RUNX3	-12352.0
ERBB2	-12320.0
NFATC2	-12294.0
ZNF599	-12232.0
PTPN4	-12220.0
RAD1	-12206.0
GATA3	-12191.0
ZNF287	-12168.0
ZNF3	-12165.0
RBBP7	-12155.0
YES1	-12142.0
PRKCQ	-12127.0
AUTS2	-12089.0
ZNF530	-12068.0
MDC1	-12059.0
WRN	-12047.0
TP53RK	-12040.0
ZNF74	-12012.0
RPA1	-12004.0
MOV10	-11991.0
PRR5	-11985.0
RORA	-11979.0
ANAPC1	-11962.0
ZNF461	-11956.0
FANCI	-11927.0
ZNF33B	-11911.0
ZNF549	-11908.0
ZNF250	-11889.0
DLL1	-11885.0
SMAD7	-11872.0
GLS	-11862.0
NUAK1	-11853.0
AKT3	-11849.0
ZNF70	-11832.0
TNRC6C	-11828.0
CAMK2D	-11816.0
ZNF43	-11813.0
ZNF682	-11811.0
ZNF500	-11806.0
DYRK2	-11799.0
DGCR8	-11798.0
ZNF286A	-11794.0
ZNF571	-11792.0
ZNF607	-11784.0
PARP1	-11764.0
SMAD3	-11745.0
CCND2	-11734.0
ZNF620	-11732.0
STAT1	-11727.0
RFC5	-11712.0
CCNE1	-11707.0
ZNF736	-11692.0
ZNF696	-11688.0
SMARCD1	-11679.0
ZNF568	-11661.0
ZNF554	-11652.0
PPP1R13B	-11636.0
BRIP1	-11605.0
ZNF337	-11599.0
NR2C2AP	-11589.0
ZNF724	-11586.0
ZNF517	-11582.0
ZNF570	-11569.0
FANCC	-11548.0
COX11	-11539.0
DDB2	-11530.0
ZNF569	-11521.0
ZNF235	-11519.0
ATRIP	-11486.0
MSH2	-11484.0
ZNF566	-11481.0
ZNF496	-11478.0
JMY	-11472.0
ZNF707	-11464.0
ZNF30	-11462.0
KRBOX4	-11452.0
ZNF419	-11446.0
ZNF740	-11444.0
RAD9A	-11435.0
ZNF136	-11433.0
FANCD2	-11424.0
RAD51D	-11415.0
CENPJ	-11406.0
ZNF773	-11396.0
PIP4K2C	-11371.0
ZNF138	-11364.0
SUPT16H	-11359.0
ZNF211	-11357.0
ZNF551	-11356.0
ZNF202	-11351.0
ZNF510	-11341.0
CUL1	-11330.0
PSMB9	-11324.0
ZNF600	-11320.0
CDC23	-11304.0
ZNF383	-11291.0
ZNF660	-11282.0
PPP2R5C	-11265.0
CDK4	-11256.0
CNOT6L	-11248.0
ZKSCAN8	-11246.0
ZNF528	-11244.0
ZNF248	-11241.0
ZNF649	-11216.0
ZNF354C	-11213.0
ZNF14	-11212.0
ZNF343	-11182.0
ZFP30	-11171.0
RUNX2	-11163.0
SSRP1	-11162.0
ATM	-11148.0
ZNF75D	-11137.0
ZNF550	-11136.0
ZNF584	-11134.0
ZNF133	-11128.0
SKI	-11113.0
ZNF519	-11101.0
ZNF540	-11097.0
WWOX	-11085.0
ZNF77	-11084.0
PLXNA4	-11083.0
ZNF184	-11077.0
PCBP4	-11063.0
ZNF548	-11049.0
ITGA4	-11043.0
ZIK1	-11040.0
ZNF19	-11034.0
ZNF678	-11020.0
ZNF621	-11018.0
KIT	-11004.0
BRD1	-10991.0
PMAIP1	-10986.0
ZNF324B	-10972.0
ANAPC5	-10967.0
ZNF226	-10966.0
ZNF432	-10951.0
ZNF703	-10910.0
ZNF441	-10905.0
TP53	-10893.0
ZNF10	-10857.0
MECP2	-10855.0
ITGAL	-10847.0
TP63	-10842.0
ZNF302	-10830.0
KAT2A	-10771.0
L3MBTL2	-10770.0
KMT2A	-10725.0
ZNF257	-10712.0
RFC4	-10702.0
ZNF23	-10692.0
ZNF180	-10670.0
ATAD2	-10660.0
ZNF253	-10652.0
PRMT6	-10628.0
NR3C2	-10625.0
FBXO32	-10607.0
ZNF585B	-10598.0
ZNF266	-10587.0
DAXX	-10575.0
ZNF563	-10567.0
ZFP1	-10563.0
ZNF790	-10520.0
MAF	-10499.0
SIN3A	-10493.0
ZNF420	-10490.0
RFC3	-10489.0
ZNF675	-10478.0
ZNF529	-10469.0
RPTOR	-10464.0
ZNF544	-10460.0
ZNF749	-10456.0
ZNF473	-10444.0
SMYD2	-10431.0
ZNF595	-10393.0
CTLA4	-10363.0
ATR	-10354.0
ZNF92	-10349.0
SMURF2	-10340.0
PSME2	-10336.0
ZNF112	-10327.0
NR1D2	-10325.0
RAD17	-10307.0
LDB1	-10303.0
ZNF778	-10297.0
ZNF680	-10286.0
AXIN1	-10285.0
IFNG	-10277.0
ZNF446	-10274.0
GPAM	-10241.0
ZNF799	-10216.0
ZFPM1	-10195.0
TCF7	-10173.0
ZFP14	-10160.0
ZNF212	-10128.0
WWP1	-10106.0
TGIF2	-10105.0
ZNF737	-10092.0
LRPPRC	-10081.0
ING5	-10037.0
ZNF626	-10014.0
PSME1	-9991.0
ZNF224	-9977.0
PERP	-9973.0
NFYB	-9964.0
RBL1	-9959.0
CAMK4	-9956.0
NOP2	-9952.0
MGA	-9948.0
ZNF436	-9945.0
EPC1	-9926.0
NR2C1	-9913.0
ZNF26	-9910.0
ZNF45	-9897.0
ZNF483	-9883.0
ZNF324	-9879.0
ZNF596	-9874.0
ZNF708	-9864.0
ZNF573	-9862.0
ZNF582	-9837.0
BMI1	-9829.0
ZNF664	-9828.0
SCO1	-9819.0
ZNF227	-9818.0
ZNF485	-9810.0
ZNF263	-9806.0
GATA2	-9800.0
MED15	-9778.0
MTOR	-9767.0
HEY2	-9752.0
EZH2	-9741.0
CHD3	-9737.0
ZNF157	-9718.0
ZNF583	-9711.0
ZNF311	-9705.0
BRD2	-9688.0
RICTOR	-9670.0
ZNF704	-9660.0
ZNF793	-9654.0
ZNF597	-9642.0
ZNF431	-9641.0
ZNF470	-9630.0
ZFP90	-9613.0
TXNIP	-9600.0
ZNF354B	-9598.0
ZNF684	-9580.0
ZNF614	-9572.0
ZNF689	-9559.0
NPM1	-9532.0
ZNF484	-9525.0
ZSCAN25	-9513.0
ZFP69	-9488.0
CCNT1	-9469.0
FOXO1	-9465.0
IGFBP3	-9455.0
ZNF506	-9443.0
ZNF41	-9405.0
ZNF17	-9349.0
EED	-9348.0
TRPC3	-9343.0
ZNF767P	-9339.0
ZNF625	-9336.0
ZNF606	-9322.0
CBX5	-9272.0
ESR2	-9250.0
PRMT1	-9229.0
MED27	-9191.0
TBP	-9167.0
ZNF141	-9154.0
ZNF677	-9144.0
PSMC4	-9127.0
ESR1	-9122.0
ZNF727	-9121.0
ZNF782	-9113.0
ZNF738	-9086.0
ZNF709	-9071.0
ZNF699	-9037.0
ZNF317	-9010.0
ZNF439	-9000.0
ZNF160	-8989.0
ZNF567	-8988.0
NR1D1	-8980.0
SESN1	-8962.0
ZNF721	-8922.0
RPA3	-8911.0
ZNF416	-8903.0
ZNF681	-8899.0
SMARCC1	-8880.0
SIRT3	-8857.0
PRDM1	-8856.0
ZNF792	-8839.0
TRIM33	-8823.0
SRC	-8820.0
ZNF433	-8780.0
ZNF79	-8769.0
ZNF140	-8760.0
ZNF619	-8735.0
ZNF440	-8730.0
AIFM2	-8727.0
ZNF717	-8709.0
ZNF331	-8698.0
PML	-8693.0
EHMT1	-8692.0
MNAT1	-8687.0
TGIF1	-8682.0
ZNF274	-8667.0
NR2C2	-8630.0
MED10	-8579.0
RORC	-8573.0
E2F5	-8568.0
EHMT2	-8558.0
MEN1	-8538.0
ZFP37	-8513.0
FOXP3	-8503.0
ZNF234	-8487.0
ZNF300	-8481.0
TAF1	-8476.0
ZNF559	-8467.0
L3MBTL1	-8461.0
PHC1	-8402.0
CDK13	-8392.0
MAPKAPK5	-8364.0
SMAD4	-8351.0
HDAC6	-8337.0
SKP2	-8279.0
HES1	-8266.0
CDKN1B	-8207.0
PRKAB2	-8172.0
PHC3	-8152.0
ZKSCAN3	-8126.0
MEAF6	-8105.0
LEF1	-8076.0
TAF4B	-8069.0
ZNF720	-8041.0
ZNF665	-7990.0
ZNF175	-7950.0
MRE11	-7923.0
GLI3	-7910.0
ZNF726	-7889.0
ZNF641	-7885.0
ZNF688	-7872.0
BBC3	-7864.0
CDC7	-7855.0
ZNF135	-7853.0
ZNF521	-7834.0
ZNF12	-7825.0
RGCC	-7821.0
ZNF585A	-7814.0
ZNF671	-7797.0
PIP4K2B	-7788.0
ERCC3	-7783.0
ZNF75A	-7752.0
RBL2	-7743.0
ZNF382	-7731.0
TNFRSF18	-7726.0
GLS2	-7702.0
ZNF702P	-7701.0
ZNF771	-7686.0
ZNF2	-7673.0
ZNF320	-7647.0
ZNF273	-7623.0
PSMA8	-7606.0
ZNF577	-7605.0
ZNF418	-7559.0
ZNF791	-7534.0
RBM14	-7497.0
ACTL6A	-7468.0
ZNF264	-7412.0
ANAPC2	-7407.0
MED24	-7387.0
YAF2	-7378.0
RAD50	-7373.0
TAF6	-7352.0
YWHAQ	-7340.0
MTA2	-7317.0
ZNF711	-7253.0
ZNF195	-7249.0
BRPF1	-7218.0
TCF3	-7215.0
IL2RA	-7161.0
GAMT	-7054.0
ZNF785	-7032.0
ZNF777	-6997.0
CCND1	-6970.0
RPS27A	-6938.0
ZNF764	-6912.0
ZNF786	-6907.0
ZNF223	-6903.0
ZNF425	-6900.0
ZNF268	-6887.0
COX19	-6882.0
MLH1	-6872.0
ZFP28	-6824.0
MED23	-6787.0
NR4A1	-6756.0
SUPT5H	-6716.0
PIDD1	-6647.0
ANAPC4	-6644.0
ZNF33A	-6630.0
ZNF691	-6627.0
BRPF3	-6615.0
ZKSCAN7	-6609.0
FBXW7	-6600.0
GAD2	-6585.0
ZNF415	-6564.0
H2BU1	-6555.0
CDK6	-6465.0
ZNF480	-6459.0
TAF15	-6454.0
RHNO1	-6437.0
PPARD	-6394.0
THRA	-6387.0
ZNF616	-6382.0
TJP1	-6374.0
FOXO6	-6367.0
ZNF208	-6363.0
RPA2	-6306.0
NELFCD	-6277.0
TFAP2E	-6266.0
AGRP	-6243.0
ZNF169	-6234.0
ZNF442	-6204.0
TCF7L2	-6185.0
ZNF610	-6184.0
RNF34	-6150.0
WWTR1	-6131.0
COX18	-6126.0
KRBA1	-6098.0
PSME4	-6087.0
KMT2E	-6073.0
CDC16	-6071.0
PSMA5	-6053.0
ZNF706	-6049.0
ZNF493	-6035.0
ZNF557	-5971.0
PCNA	-5969.0
ZNF662	-5963.0
ZNF154	-5946.0
TAF2	-5945.0
ZNF543	-5942.0
ZNF398	-5842.0
SCMH1	-5839.0
NOC2L	-5831.0
ZNF761	-5813.0
E2F7	-5780.0
SETD1A	-5744.0
PSMB10	-5735.0
ZNF713	-5668.0
ZNF514	-5664.0
ZNF718	-5657.0
ZNF101	-5614.0
TNRC6A	-5613.0
MAMLD1	-5584.0
ZNF658	-5581.0
ZNF34	-5577.0
ZFP69B	-5558.0
ZNF71	-5533.0
ZNF589	-5519.0
PMS2	-5514.0
ARID1B	-5504.0
TNKS1BP1	-5490.0
MED30	-5484.0
ZNF25	-5459.0
ZNF417	-5416.0
BLK	-5388.0
ZNF99	-5349.0
ZNF615	-5323.0
ZNF547	-5291.0
PSMA3	-5285.0
RABGGTB	-5240.0
ZNF285	-5239.0
CDKN2A	-5236.0
ZNF37A	-5230.0
NOTCH4	-5229.0
CCNT2	-5205.0
BTG1	-5201.0
ANAPC7	-5181.0
ZKSCAN4	-5161.0
RARG	-5153.0
ZNF443	-5146.0
RBBP8	-5105.0
NR4A3	-5082.0
TRIM28	-5056.0
PPARGC1B	-5047.0
COX20	-5018.0
ZNF155	-5014.0
CDK2	-5006.0
ANAPC10	-5000.0
E2F6	-4979.0
SOCS4	-4974.0
ZNF124	-4952.0
ZNF430	-4837.0
ZNF546	-4802.0
TP73	-4754.0
ZNF692	-4722.0
ZNF700	-4710.0
BLM	-4690.0
ZNF611	-4678.0
ZNF492	-4623.0
CBX2	-4617.0
ZNF564	-4519.0
TNRC6B	-4518.0
CHD4	-4515.0
TAF5	-4514.0
ZNF460	-4477.0
NR1I2	-4435.0
ZNF197	-4430.0
ZNF426	-4382.0
SCO2	-4351.0
CHEK2	-4350.0
SMARCE1	-4315.0
ZNF561	-4292.0
CNOT1	-4265.0
SIN3B	-4205.0
SIRT1	-4197.0
SMARCC2	-4137.0
PCGF2	-4135.0
RING1	-4063.0
RMI2	-4050.0
ZNF486	-4043.0
MED1	-4036.0
POLR2D	-4024.0
ARID2	-3932.0
ZNF233	-3931.0
CDK9	-3927.0
YEATS4	-3919.0
NELFA	-3886.0
CNOT7	-3880.0
SMARCB1	-3869.0
PRELID3A	-3832.0
TEAD2	-3774.0
ZNF334	-3744.0
ZSCAN32	-3733.0
ZNF215	-3708.0
PAX5	-3638.0
NR1H3	-3597.0
ZNF676	-3587.0
ZNF701	-3558.0
SESN3	-3546.0
GPX2	-3533.0
ZNF350	-3507.0
ZNF655	-3460.0
ZNF556	-3455.0
TOPBP1	-3450.0
CASP10	-3446.0
BARD1	-3419.0
BCL2L14	-3367.0
PCGF5	-3312.0
ZNF714	-3298.0
ZNF624	-3294.0
RXRB	-3276.0
UXT	-3252.0
PIN1	-3188.0
ZFP2	-3134.0
ZNF221	-3101.0
POLR2A	-3092.0
PSMB8	-3076.0
ZNF670	-3075.0
CTSV	-3036.0
POLR2H	-2942.0
TAF11	-2938.0
GTF2H4	-2916.0
GTF2H1	-2913.0
DNA2	-2858.0
CASP6	-2831.0
HIVEP3	-2798.0
RAD51	-2767.0
PLK2	-2748.0
ZNF555	-2741.0
SMARCA2	-2737.0
CNOT10	-2718.0
TTC5	-2650.0
ZNF490	-2630.0
ABCA6	-2612.0
TAF9B	-2599.0
SMURF1	-2591.0
ZNF605	-2576.0
ZNF18	-2548.0
POLR2B	-2523.0
ZNF772	-2509.0
CHEK1	-2481.0
CASP2	-2471.0
RABGGTA	-2462.0
KAT2B	-2414.0
SUZ12	-2409.0
DDIT4	-2395.0
PIP4K2A	-2365.0
H19	-2361.0
ZNF860	-2350.0
OCLN	-2327.0
GTF2H3	-2235.0
FZR1	-2233.0
ZNF839	-2202.0
ANAPC16	-2123.0
TSC1	-2118.0
CNOT2	-2090.0
CALM1	-2081.0
CDK8	-1971.0
PHF20	-1921.0
KCTD1	-1890.0
RBBP4	-1870.0
HSPD1	-1860.0
TAF3	-1850.0
RELA	-1803.0
POLR2K	-1783.0
GATAD2B	-1759.0
NR2F1	-1717.0
ZNF468	-1709.0
TAF4	-1698.0
RFFL	-1683.0
ZNF669	-1660.0
ZNF28	-1618.0
NR4A2	-1601.0
EXO1	-1586.0
COX14	-1496.0
BGLAP	-1473.0
CREB1	-1378.0
CDK12	-1356.0
ZNF750	-1354.0
CYCS	-1334.0
CNOT4	-1286.0
SETD9	-1240.0
TCF12	-1233.0
MDM4	-1230.0
H2AZ2	-1209.0
CDK5R1	-1089.0
STUB1	-1032.0
ZNF627	-1022.0
AGO3	-1011.0
ZNF562	-962.0
TCEA1	-943.0
ZNF565	-941.0
GPS2	-889.0
PSMC5	-863.0
MED6	-842.0
TSC2	-804.0
UBE2I	-764.0
SKIL	-725.0
MOBP	-714.0
RRAGB	-713.0
PCGF6	-689.0
ZNF558	-678.0
CDC27	-651.0
PSMA4	-616.0
NPPA	-584.0
MAML2	-582.0
MBD3	-528.0
ZNF716	-489.0
MEF2C	-293.0
PPP2R1B	-241.0
MED14	-203.0
RRM2	-183.0
ZNF587	-164.0
ZNF200	-154.0
HUS1	-145.0
ZNF222	-84.0
ZNF347	-31.0
BRD7	-10.0
MT-CO3	40.0
MT-CO2	48.0
KMT2C	63.0
COX16	132.0
WDR5	155.0
KLF4	157.0
APOE	218.0
MED7	224.0
ABL1	226.0
TCF7L1	275.0
ZNF100	276.0
TRIAP1	281.0
MYB	302.0
ZNF776	367.0
NELFB	374.0
MLST8	376.0
CSF1R	394.0
POLR2I	396.0
PPP1R13L	399.0
AKT2	433.0
PLAGL1	446.0
CCNB1	467.0
NR3C1	511.0
YY1	537.0
COX7C	564.0
CCNA1	585.0
HDAC1	587.0
CLDN5	650.0
MT-CO1	684.0
BANP	687.0
COX6C	706.0
SETD1B	736.0
CCNH	774.0
KAT6A	794.0
PPARA	813.0
AURKB	846.0
RBBP5	1037.0
ZNF429	1053.0
UBA52	1121.0
KMT2B	1179.0
GCK	1193.0
TAF9	1250.0
PRKAB1	1302.0
KAT5	1314.0
ITCH	1318.0
ZNF394	1319.0
PRKAA1	1322.0
ZKSCAN5	1336.0
HDAC9	1359.0
THRB	1429.0
MED31	1462.0
CDK1	1540.0
TPX2	1551.0
PSMD10	1559.0
ATXN3	1601.0
SFN	1615.0
POLR2C	1616.0
ELF1	1630.0
CCNA2	1685.0
KCTD15	1758.0
TNFRSF10A	1815.0
PVALB	1839.0
NR1I3	1855.0
CCNC	1877.0
CAMK2G	1921.0
ZNF658B	1948.0
ZNF613	1957.0
CAV1	1969.0
PSMC3	1976.0
PRKAG2	2015.0
MED12	2034.0
CBFB	2078.0
ATF2	2085.0
CNOT11	2102.0
TAF7	2139.0
OPRM1	2161.0
ZKSCAN1	2166.0
CBX4	2222.0
NBN	2267.0
CHM	2273.0
HDAC10	2280.0
STK11	2289.0
MYC	2304.0
PSMB4	2523.0
MED13	2533.0
PSMC2	2598.0
MYBL2	2601.0
ELF2	2606.0
PSMD14	2611.0
DEK	2676.0
NRBP1	2786.0
SLC38A9	2807.0
POMC	2855.0
E2F8	2856.0
ZNF471	2869.0
CCNK	2877.0
ZNF586	2878.0
SUPT4H1	2890.0
CDC26	2923.0
ZNF770	2964.0
GTF2H2	2984.0
AGO2	2995.0
VENTX	3057.0
GATAD2A	3075.0
HDAC8	3079.0
MED17	3084.0
RAD9B	3090.0
BTG2	3111.0
KMT2D	3203.0
HTT	3209.0
MED4	3215.0
SESN2	3311.0
AURKA	3330.0
ZNF445	3333.0
PSMB1	3374.0
CREBBP	3423.0
PSMD5	3426.0
PRDX2	3428.0
ZNF189	3487.0
NFYA	3506.0
POLR2G	3508.0
RNF2	3513.0
ZNF205	3530.0
SURF1	3532.0
ERCC2	3547.0
PRMT5	3600.0
AKT1	3614.0
KRAS	3702.0
FAS	3712.0
JUN	3722.0
ZNF668	3725.0
BIRC5	3738.0
ZNF667	3739.0
DPY30	3757.0
MAPK11	3826.0
TMEM219	3845.0
NELFE	3860.0
GTF2H5	3874.0
ZNF354A	3889.0
RBX1	3934.0
ZNF747	3949.0
CSNK2B	3969.0
PPARGC1A	3988.0
ZNF333	4007.0
CBX6	4033.0
PSMB2	4084.0
COX4I1	4191.0
CASP1	4224.0
CTSL	4231.0
MAX	4243.0
SKP1	4287.0
MDM2	4312.0
SEM1	4348.0
KCTD6	4371.0
SOD2	4390.0
MED26	4395.0
TACO1	4406.0
ING2	4415.0
UBC	4439.0
LAMTOR4	4441.0
COX7B	4465.0
CDKN1A	4511.0
TBL1XR1	4556.0
PPP2R1A	4589.0
SGK1	4595.0
POLR2F	4604.0
PSMD3	4618.0
NDRG1	4647.0
HDAC3	4673.0
ZNF552	4685.0
ZNF20	4697.0
NOTCH1	4704.0
HDAC5	4710.0
SMARCA4	4733.0
UBE2S	4746.0
ZNF774	4747.0
HDAC11	4756.0
CNOT6	4799.0
DLX6	4817.0
CBX3	4825.0
ARID1A	4830.0
AR	4840.0
CCNG1	4881.0
ZNF282	4892.0
SMAD2	4905.0
DDIT3	4906.0
RFC2	4948.0
GTF2F1	4951.0
RRAGC	4954.0
CDC25C	4969.0
H2AC20	4972.0
NR2F6	4984.0
ELL	5009.0
ZNF775	5041.0
MAPKAP1	5057.0
CTSK	5059.0
COX6A1	5095.0
UBE2C	5101.0
GPRIN1	5131.0
CCNE2	5143.0
TGFB1	5153.0
SNW1	5201.0
CDK7	5211.0
CRADD	5216.0
NOTCH2	5272.0
MED16	5278.0
POLR2L	5305.0
H2BC15	5312.0
PTPN11	5314.0
CNOT3	5320.0
PSMA2	5339.0
H2BC9	5394.0
MAML1	5404.0
GTF2F2	5434.0
CBX8	5448.0
FOS	5460.0
USP9X	5464.0
PRKAG1	5476.0
HDAC2	5482.0
TP53BP2	5532.0
RYBP	5535.0
PBRM1	5566.0
G6PC	5568.0
YWHAZ	5624.0
AGO1	5654.0
COX6B1	5667.0
PF4	5707.0
PTPN1	5722.0
KDM5B	5736.0
RNF111	5749.0
PSMD8	5757.0
PRELID1	5790.0
HIPK1	5855.0
NCOR1	5887.0
BAX	5916.0
ESRRA	5943.0
PSMD13	5948.0
ZNF213	5950.0
THBS1	5951.0
PSMD7	5963.0
PSMA6	5970.0
STEAP3	5996.0
ASH2L	6001.0
ZNF385A	6014.0
BID	6020.0
H2AZ1	6036.0
HIPK2	6078.0
HDAC7	6122.0
EP300	6129.0
IRAK1	6131.0
PDPK1	6136.0
ANAPC11	6161.0
COX5A	6168.0
CTDP1	6180.0
CSNK2A1	6199.0
TIGAR	6204.0
COX5B	6207.0
MED25	6209.0
PSMD11	6231.0
RRAGA	6244.0
BRCA1	6248.0
NFKB1	6277.0
GP1BA	6279.0
GPI	6284.0
E2F4	6300.0
USP7	6323.0
E2F1	6343.0
YWHAB	6385.0
CSNK2A2	6388.0
FOXO4	6391.0
CTNNB1	6408.0
RARA	6429.0
CITED2	6457.0
TP53INP1	6458.0
NDUFA4	6459.0
TAL1	6518.0
SREBF1	6539.0
PSMD12	6556.0
COX8A	6611.0
CCNG2	6629.0
GSK3B	6634.0
PSMC6	6635.0
UBB	6639.0
PSMF1	6659.0
POLR2J	6671.0
PLK3	6680.0
ZNF230	6689.0
H3C15	6699.5
TWIST2	6721.0
MED20	6743.0
UBE2E1	6759.0
SATB2	6781.0
RRM2B	6798.0
JUNB	6806.0
PSMB6	6813.0
SUMO1	6889.0
ZNF710	6900.0
SMARCD2	6914.0
RMI1	6947.0
PSMC1	7021.0
PRDX1	7030.0
PSMA7	7096.0
PRKCB	7097.0
TAF10	7110.0
PSMB3	7171.0
ZNF267	7203.0
TAF13	7217.0
PSMD1	7241.0
H2BC17	7285.0
ELOA	7312.0
PSMA1	7329.0
BCL2L11	7384.0
H2BC4	7389.0
PSMD2	7411.0
NR1H2	7415.0
ZFHX3	7425.0
VEGFA	7467.0
ELOB	7482.0
SERPINE1	7483.0
CCND3	7487.0
MAPK1	7493.0
RXRA	7495.0
ELOC	7519.0
RUNX1	7529.0
MED8	7535.0
POLR2E	7563.0
LAMTOR2	7567.0
ZNF746	7573.0
LAMTOR3	7574.0
PSMD9	7620.0
NFYC	7653.0
ITGA5	7659.0
RHEB	7669.0
MYL9	7703.0
PPP2CB	7712.0
COX7A2L	7719.0
PPM1D	7810.0
SMAD6	7835.0
CITED4	7844.0
PSMD6	7846.0
NEDD4L	7875.0
TBL1X	7887.0
NOTCH3	7899.0
H2BC11	7912.0
H2AC6	7934.0
TNFRSF10C	7960.0
TOP3A	7973.0
TAF12	7977.0
NCOR2	7985.0
CEBPB	7997.0
H2BC5	8003.0
KMT5A	8005.0
NRBF2	8076.0
PSMB5	8101.0
LBR	8102.0
TXNRD1	8192.0
SP1	8193.0
PPM1A	8200.0
CNOT8	8227.0
PPP2CA	8234.0
PSME3	8251.0
TXN	8285.0
LMO2	8307.0
TNFRSF10B	8321.0
VDR	8348.0
PSMD4	8402.0
GATA1	8410.0
PTEN	8460.0
TFDP1	8470.0
PSMB7	8485.0
LAMTOR5	8498.0
SMAD1	8511.0
PRDX5	8531.0
NR6A1	8553.0
ARID3A	8584.0
CDK5	8616.0
UBE2D3	8640.0
YWHAH	8649.0
H3-3A	8661.0
SMARCD3	8668.0
FOXO3	8682.0
RB1	8707.0
JAG1	8743.0
LGALS3	8752.0
RRAGD	8753.0
RBPJ	8770.0
CDKN2B	8836.0
MAP2K6	8887.0
TGFA	8889.0
SPI1	8891.0
ITGA2B	8893.0
PINK1	8941.0
MAPK3	8953.0
MAML3	8957.0
HDAC4	8960.0
ANAPC15	8968.0
TP53I3	8979.0
RETN	8998.0
ZNF697	9002.0
G6PD	9004.0
APAF1	9015.0
CARM1	9020.0
SLC2A3	9021.0
PHC2	9043.0
YWHAE	9045.0
H2BC12	9051.0
AGO4	9070.0
TNFRSF10D	9072.0
GADD45A	9083.0
FKBP5	9091.0
MAPK14	9104.0
CAT	9123.0
BCL6	9175.0
UBE2D1	9187.0
GSR	9235.0
YWHAG	9264.0
H2BC21	9283.0
BNIP3L	9329.0
H2AJ	9374.0
NLRC4	9406.0
LAMTOR1	9411.0
PRKACA	9429.0
NFE2	9431.0
SOCS3	9476.0
CR1	9486.0
PPARG	9522.0

---

Cellular responses to external stimuli

Cellular responses to external stimuli

	169
set	Cellular responses to external stimuli
setSize	506
pANOVA	1.91e-08
s.dist	0.146
p.adjustANOVA	3.89e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H1-2	9491
GRB10	9439
LAMTOR1	9411
H2AJ	9374
PRDX3	9366
LMNB1	9345
GPX1	9314
ATP6V1A	9302
H2BC21	9283
NCF4	9268
ATP6V0D1	9245
GSR	9235
NCF2	9190
UBE2D1	9187
DCTN2	9157
ATP6V0C	9127
CAT	9123
MAPK14	9104
FKBP5	9091
AGO4	9070

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H1-2	9491.0
GRB10	9439.0
LAMTOR1	9411.0
H2AJ	9374.0
PRDX3	9366.0
LMNB1	9345.0
GPX1	9314.0
ATP6V1A	9302.0
H2BC21	9283.0
NCF4	9268.0
ATP6V0D1	9245.0
GSR	9235.0
NCF2	9190.0
UBE2D1	9187.0
DCTN2	9157.0
ATP6V0C	9127.0
CAT	9123.0
MAPK14	9104.0
FKBP5	9091.0
AGO4	9070.0
ATP6V1B2	9057.0
H2BC12	9051.0
ATP6V1D	9047.0
YWHAE	9045.0
PHC2	9043.0
CYBB	9031.0
ANAPC15	8968.0
MAPK3	8953.0
ERO1A	8943.0
PRDX6	8937.0
MTF1	8925.0
MAP2K6	8887.0
CDKN2B	8836.0
NUP58	8820.0
RRAGD	8753.0
MAP2K3	8748.0
RB1	8707.0
H3-3A	8661.0
UBE2D3	8640.0
E2F2	8601.0
ATP6V0B	8598.0
CAPZA2	8597.0
ATP6V0E1	8596.0
KDM6B	8577.0
ATP6V1C1	8539.0
PRDX5	8531.0
LAMTOR5	8498.0
PSMB7	8485.0
EIF2AK1	8482.0
TFDP1	8470.0
P4HB	8440.0
MAP4K4	8425.0
PSMD4	8402.0
DCTN4	8387.0
MAPKAPK3	8382.0
BAG4	8328.0
TXN	8285.0
PSME3	8251.0
SP1	8193.0
TXNRD1	8192.0
HSBP1	8173.0
CAPZA1	8135.0
PSMB5	8101.0
STAT3	8098.0
ETS2	8092.0
HSPA1A	8071.0
DNAJB6	8066.0
ATP6V1H	8064.0
ARNT	8047.0
ATP6V1E1	8035.0
CAPZB	8015.0
H2BC5	8003.0
CEBPB	7997.0
H2AC6	7934.0
NUP214	7921.0
H2BC11	7912.0
EPAS1	7886.0
AKT1S1	7865.0
CDKN2D	7853.0
PSMD6	7846.0
CSRP1	7829.0
DYNC1I2	7735.0
DNAJC7	7701.0
RPS6KA1	7695.0
MAP3K5	7682.0
RHEB	7669.0
MT1F	7632.0
PSMD9	7620.0
ACTR10	7605.0
LAMTOR3	7574.0
LAMTOR2	7567.0
TXNRD2	7526.0
ELOC	7519.0
MAPK1	7493.0
H1-0	7492.0
ELOB	7482.0
VEGFA	7467.0
HIF1A	7436.0
PSMD2	7411.0
HIGD1A	7394.0
H2BC4	7389.0
BMT2	7350.0
NCF1	7334.0
PSMA1	7329.0
DCTN6	7300.0
H2BC17	7285.0
PSMD1	7241.0
TCIRG1	7188.0
RPL26L1	7176.0
PSMB3	7171.0
PSMA7	7096.0
HSPA2	7081.0
PRDX1	7030.0
HSPA5	7029.0
PSMC1	7021.0
ACTR1A	7002.0
DYNC1LI1	6941.0
CYBA	6922.0
VCP	6886.0
MAP2K4	6866.0
PSMB6	6813.0
CDKN2C	6811.0
UBE2E1	6759.0
EIF2S3	6747.0
H3C15	6699.5
PSMF1	6659.0
E2F3	6650.0
UBB	6639.0
PSMC6	6635.0
GSK3B	6634.0
EGLN1	6604.0
PSMD12	6556.0
IGFBP7	6545.0
HSPA6	6514.0
HSPA1B	6470.0
CITED2	6457.0
BAG1	6396.0
E2F1	6343.0
NFKB1	6277.0
KPTN	6265.0
RRAGA	6244.0
ATF4	6237.0
PSMD11	6231.0
EIF2S2	6175.0
ANAPC11	6161.0
EP300	6129.0
HSF1	6063.0
H2AZ1	6036.0
DCTN3	5994.0
PPP1R15A	5981.0
PSMA6	5970.0
PSMD7	5963.0
DYNLL1	5952.0
PSMD13	5948.0
ATP6V1F	5878.0
PSMD8	5757.0
SEC13	5748.0
ATP6V1E2	5730.0
AGO1	5654.0
FNIP1	5603.0
DNAJA2	5589.0
CEBPG	5466.0
FOS	5460.0
MT1X	5452.0
CBX8	5448.0
DNAJA1	5425.0
RPS9	5421.0
H2BC9	5394.0
UBN1	5358.0
HSPA4	5350.0
PSMA2	5339.0
H2BC15	5312.0
RAE1	5164.0
CCNE2	5143.0
UBE2C	5101.0
DCTN1	5078.0
TERF2IP	5040.0
H2AC20	4972.0
RRAGC	4954.0
ID1	4927.0
DDIT3	4906.0
AR	4840.0
UBE2S	4746.0
UBE2D2	4657.0
TXN2	4651.0
PSMD3	4618.0
TINF2	4592.0
NUP50	4521.0
CDKN1A	4511.0
NPRL3	4510.0
RPL3L	4503.0
LAMTOR4	4441.0
UBC	4439.0
ERF	4400.0
SOD2	4390.0
SEM1	4348.0
ATOX1	4338.0
MAPK10	4325.0
MDM2	4312.0
EIF2S1	4279.0
DYNC1LI2	4273.0
DYNC1I1	4187.0
PTGES3	4125.0
PSMB2	4084.0
MAPKAPK2	4054.0
CBX6	4033.0
RBX1	3934.0
ATP6V1G1	3931.0
MAPK11	3826.0
JUN	3722.0
MINK1	3687.0
VHL	3674.0
FLCN	3622.0
EGLN2	3578.0
RNF2	3513.0
PRDX2	3428.0
PSMD5	3426.0
CREBBP	3423.0
MIOS	3378.0
PSMB1	3374.0
DEDD2	3327.0
SESN2	3311.0
HSPA1L	3102.0
NUP98	3101.0
RPS6KA2	3087.0
NUP37	3074.0
VENTX	3057.0
NUDT2	2988.0
RPS6KA3	2973.0
CDC26	2923.0
SLC38A9	2807.0
RPS19BP1	2709.0
PSMD14	2611.0
PSMC2	2598.0
CUL2	2526.0
PSMB4	2523.0
NBN	2267.0
HSPA12B	2254.0
CBX4	2222.0
H1-4	2207.0
MRPL18	2144.0
ATF2	2085.0
RPS27L	2061.0
PSMC3	1976.0
CAMK2G	1921.0
CXCL8	1729.0
CCNA2	1685.0
MAP2K7	1654.0
PSMD10	1559.0
CCS	1538.0
HSP90AA1	1326.0
KAT5	1314.0
NOX5	1175.0
WDR24	1150.0
UBA52	1121.0
NOX4	1114.0
FKBP4	832.0
NUP62	769.0
ATP7A	694.0
GPX3	680.0
CCNA1	585.0
NR3C1	511.0
RPS4Y1	424.0
MLST8	376.0
GSTP1	135.0
HMGA1	117.0
DEPDC5	102.0
EIF2AK4	41.0
RPL36AL	32.0
RPLP1	19.0
HIKESHI	-103.0
RPS24	-263.0
FAU	-362.0
MT1E	-432.0
EGLN3	-437.0
PSMA4	-616.0
CDC27	-651.0
RRAGB	-713.0
RANBP2	-820.0
PSMC5	-863.0
DNAJA4	-881.0
RPL15	-963.0
RPLP0	-1000.0
AGO3	-1011.0
HSPA13	-1157.0
RPL8	-1187.0
H2AZ2	-1209.0
MDM4	-1230.0
ST13	-1254.0
CYCS	-1334.0
MAPK7	-1337.0
RPS26	-1430.0
RPL28	-1462.0
RPL22L1	-1619.0
RPS13	-1749.0
HSPA12A	-1760.0
RELA	-1803.0
RBBP4	-1870.0
RPL9	-1872.0
RPL7	-1955.0
RPS8	-2083.0
STIP1	-2094.0
ANAPC16	-2123.0
ATP6V1C2	-2219.0
FZR1	-2233.0
SUZ12	-2409.0
HIF3A	-2519.0
RPL27	-2855.0
FNIP2	-2881.0
HSPA4L	-2948.0
RPL39	-3006.0
NUP85	-3049.0
PSMB8	-3076.0
BAG3	-3170.0
IMPACT	-3210.0
RPL23	-3314.0
RPL6	-3354.0
RPL13	-3431.0
GPX2	-3533.0
RPL4	-3582.0
TERF1	-3601.0
RPL29	-3611.0
RPL7A	-3665.0
RPS15	-3673.0
RPL37A	-3946.0
DYNLL2	-3980.0
RING1	-4063.0
RPS21	-4079.0
DCTN5	-4086.0
SIRT1	-4197.0
POT1	-4355.0
TERF2	-4464.0
RPS2	-4499.0
HIF1AN	-4510.0
TNRC6B	-4518.0
RPL31	-4541.0
CBX2	-4617.0
RPS16	-4669.0
RPS3A	-4694.0
RPS28	-4713.0
RPL5	-4728.0
RPL22	-4740.0
SOD1	-4862.0
BAG5	-4887.0
DNAJC2	-4961.0
RPS7	-4968.0
ANAPC10	-5000.0
CDK2	-5006.0
RPL18	-5080.0
EEF1A1	-5087.0
ANAPC7	-5181.0
CDKN2A	-5236.0
PSMA3	-5285.0
RPL36	-5287.0
ATF5	-5305.0
SZT2	-5322.0
RPL17	-5431.0
RPS14	-5463.0
NUP42	-5564.0
TNRC6A	-5613.0
DNAJB1	-5672.0
RPS5	-5691.0
PSMB10	-5735.0
RPS15A	-5742.0
RPS10	-5793.0
RPL24	-5799.0
SCMH1	-5839.0
RPL38	-5840.0
TRIB3	-5843.0
RPS3	-5914.0
RPS12	-5987.0
RPL35A	-6015.0
PSMA5	-6053.0
SEH1L	-6069.0
RPL18A	-6070.0
CDC16	-6071.0
PSME4	-6087.0
RPS6	-6160.0
RPS17	-6247.0
RPL27A	-6257.0
RPL11	-6261.0
RPL19	-6281.0
RPS4X	-6285.0
RPS23	-6292.0
RPA2	-6306.0
NUP153	-6321.0
RPSA	-6323.0
RPS25	-6365.0
RPL37	-6375.0
RPL21	-6458.0
CDK6	-6465.0
RLN1	-6482.0
RPL10	-6534.0
EP400	-6550.0
H2BU1	-6555.0
RPL26	-6612.0
ANAPC4	-6644.0
RPL10A	-6686.0
RPL32	-6709.0
RPL14	-6710.0
RPL34	-6802.0
HSP90AB1	-6863.0
RPL41	-6866.0
RPS27A	-6938.0
RPS19	-6965.0
MT2A	-6990.0
RPL30	-7020.0
TPR	-7028.0
RPL12	-7053.0
MAPK9	-7068.0
RPLP2	-7087.0
POM121C	-7188.0
WTIP	-7208.0
RPS11	-7243.0
RAD50	-7373.0
RPL36A	-7376.0
ANAPC2	-7407.0
PSMA8	-7606.0
DYNC1H1	-7685.0
RPS18	-7744.0
NUP133	-7762.0
ACD	-7800.0
MRE11	-7923.0
AJUBA	-7927.0
RPS29	-7940.0
BAG2	-7997.0
RPL35	-8092.0
PHC3	-8152.0
CDKN1B	-8207.0
RPL13A	-8212.0
HSPA7	-8236.0
POM121	-8299.0
ASNS	-8316.0
HDAC6	-8337.0
MAPKAPK5	-8364.0
AAAS	-8389.0
PHC1	-8402.0
NUP54	-8479.0
EHMT2	-8558.0
RPL3	-8561.0
EHMT1	-8692.0
RPL39L	-8805.0
SH3BP4	-8881.0
RPS20	-8886.0
GPX7	-8901.0
RPA3	-8911.0
SESN1	-8962.0
PSMC4	-9127.0
WDR59	-9240.0
EED	-9348.0
HSPA14	-9380.0
HSPH1	-9407.0
MAPK8	-9428.0
ATP6V1G2	-9515.0
NUP43	-9517.0
RPL23A	-9567.0
HIRA	-9628.0
ATF3	-9677.0
EZH2	-9741.0
RPS27	-9756.0
MTOR	-9767.0
HSPA9	-9780.0
ASF1A	-9781.0
BMI1	-9829.0
PSME1	-9991.0
SERPINH1	-10121.0
CCAR2	-10156.0
NUP155	-10233.0
PSME2	-10336.0
ATR	-10354.0
GCN1	-10372.0
NUP107	-10421.0
RPTOR	-10464.0
NUP160	-10557.0
CABIN1	-10590.0
NUP35	-10611.0
NR3C2	-10625.0
ITFG2	-10719.0
NUP210	-10726.0
LIMD1	-10791.0
TP53	-10893.0
HSPA8	-10922.0
C12orf66	-10960.0
ANAPC5	-10967.0
ATM	-11148.0
CDK4	-11256.0
CDC23	-11304.0
NUP205	-11321.0
PSMB9	-11324.0
ETS1	-11386.0
NUP88	-11397.0
ATP6V0E2	-11555.0
NPRL2	-11604.0
NUP93	-11620.0
NUP188	-11624.0
TNIK	-11674.0
CCNE1	-11707.0
CAMK2D	-11816.0
TNRC6C	-11828.0
ANAPC1	-11962.0
MOV10	-11991.0
RPA1	-12004.0
RBBP7	-12155.0
NDC1	-12173.0
TNFRSF21	-12254.0
TFDP2	-12364.0

---

COPI-independent Golgi-to-ER retrograde traffic

COPI-independent Golgi-to-ER retrograde traffic

	133
set	COPI-independent Golgi-to-ER retrograde traffic
setSize	33
pANOVA	2.11e-08
s.dist	0.563
p.adjustANOVA	4.24e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PLA2G4A	9180
DCTN2	9157
GALNT2	8843
BICD2	8746
CAPZA2	8597
DCTN4	8387
RAB6A	8148
CAPZA1	8135
CAPZB	8015
RAB18	7801
DYNC1I2	7735
ACTR10	7605
DCTN6	7300
ACTR1A	7002
PAFAH1B2	6942
DYNC1LI1	6941
GALNT1	6508
RAB6B	6053
DCTN3	5994
DYNLL1	5952

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PLA2G4A	9180
DCTN2	9157
GALNT2	8843
BICD2	8746
CAPZA2	8597
DCTN4	8387
RAB6A	8148
CAPZA1	8135
CAPZB	8015
RAB18	7801
DYNC1I2	7735
ACTR10	7605
DCTN6	7300
ACTR1A	7002
PAFAH1B2	6942
DYNC1LI1	6941
GALNT1	6508
RAB6B	6053
DCTN3	5994
DYNLL1	5952
RAB3GAP1	5768
PAFAH1B1	5470
DCTN1	5078
AGPAT3	4809
RAB3GAP2	4429
PAFAH1B3	4417
DYNC1LI2	4273
DYNC1I1	4187
DYNLL2	-3980
DCTN5	-4086
BICD1	-7365
DYNC1H1	-7685
PLA2G6	-12122

---

ER-Phagosome pathway

ER-Phagosome pathway

	329
set	ER-Phagosome pathway
setSize	83
pANOVA	2.17e-08
s.dist	0.355
p.adjustANOVA	4.3e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CD36	9444
TLR2	9103
CD14	9097
TLR4	9016
TLR1	8932
TLR6	8840
LY96	8795
SNAP23	8628
PSMB7	8485
PSMD4	8402
PSME3	8251
VAMP3	8222
MYD88	8136
PSMB5	8101
CHUK	7966
PSMD6	7846
PSMD9	7620
PSMD2	7411
PSMA1	7329
PSMD1	7241

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CD36	9444
TLR2	9103
CD14	9097
TLR4	9016
TLR1	8932
TLR6	8840
LY96	8795
SNAP23	8628
PSMB7	8485
PSMD4	8402
PSME3	8251
VAMP3	8222
MYD88	8136
PSMB5	8101
CHUK	7966
PSMD6	7846
PSMD9	7620
PSMD2	7411
PSMA1	7329
PSMD1	7241
BTK	7206
PSMB3	7171
PSMA7	7096
PSMC1	7021
SEC61B	7013
PSMB6	6813
PSMF1	6659
UBB	6639
PSMC6	6635
PSMD12	6556
SEC61A1	6449
CALR	6340
PSMD11	6231
PSMA6	5970
PSMD7	5963
PSMD13	5948
SEC22B	5873
PSMD8	5757
TIRAP	5640
IKBKG	5377
PSMA2	5339
VAMP8	5218
SEC61G	4708
PSMD3	4618
UBC	4439
SEM1	4348
PDIA3	4128
PSMB2	4084
PSMD5	3426
PSMB1	3374
TAPBP	3010
PSMD14	2611
PSMC2	2598
PSMB4	2523
PSMC3	1976
PSMD10	1559
UBA52	1121
HLA-C	1018
HLA-B	649
STX4	606
PSMA4	-616
PSMC5	-863
HLA-G	-2457
HLA-A	-2573
PSMB8	-3076
HLA-H	-3889
HLA-E	-4415
PSMA3	-5285
IKBKB	-5386
PSMB10	-5735
PSMA5	-6053
PSME4	-6087
B2M	-6920
RPS27A	-6938
PSMA8	-7606
PSMC4	-9127
PSME1	-9991
PSME2	-10336
TAP1	-10787
SEC61A2	-10798
HLA-F	-11138
PSMB9	-11324
TAP2	-11807

---

Class I MHC mediated antigen processing & presentation

Class I MHC mediated antigen processing & presentation

	188
set	Class I MHC mediated antigen processing & presentation
setSize	350
pANOVA	2.99e-08
s.dist	0.172
p.adjustANOVA	5.84e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SOCS3	9476
CD36	9444
FBXO9	9416
FBXL5	9410
FCGR1A	9323
NCF4	9268
NCF2	9190
UBE2D1	9187
KLHL2	9174
UBE2J1	9170
TLR2	9103
CD14	9097
FCGR1B	9053
CYBB	9031
TLR4	9016
TLR1	8932
TRIM71	8867
TLR6	8840
MKRN1	8817
LY96	8795

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SOCS3	9476
CD36	9444
FBXO9	9416
FBXL5	9410
FCGR1A	9323
NCF4	9268
NCF2	9190
UBE2D1	9187
KLHL2	9174
UBE2J1	9170
TLR2	9103
CD14	9097
FCGR1B	9053
CYBB	9031
TLR4	9016
TLR1	8932
TRIM71	8867
TLR6	8840
MKRN1	8817
LY96	8795
UBE2D3	8640
SNAP23	8628
FBXL19	8620
TRAF7	8612
CDC34	8611
SIAH2	8578
UBE2R2	8548
RNF130	8510
PSMB7	8485
PSMD4	8402
RNF41	8389
CTSS	8372
RNF217	8367
RNF144B	8364
UBAC1	8353
UBE2J2	8268
PSME3	8251
VAMP3	8222
MYD88	8136
ATG7	8134
SEC24D	8115
PSMB5	8101
CHUK	7966
UBE2W	7929
RNF7	7913
NEDD4L	7875
WSB1	7862
PSMD6	7846
UBA3	7767
NPEPPS	7686
ZNRF1	7675
UBE2H	7663
SEC24A	7660
PSMD9	7620
UBE2L3	7561
ELOC	7519
LRRC41	7515
FBXO7	7498
PJA2	7486
ELOB	7482
UBE2M	7477
PSMD2	7411
UBE2F	7341
SEC23A	7335
NCF1	7334
PSMA1	7329
RNF182	7310
UBE2A	7309
PSMD1	7241
BTK	7206
PSMB3	7171
PSMA7	7096
UBA1	7089
HSPA5	7029
PSMC1	7021
SEC61B	7013
UBE2B	7003
ITGB5	6923
CYBA	6922
TRIP12	6921
UBE2K	6884
CUL3	6821
PSMB6	6813
RNF123	6802
RNF19B	6764
UBE2E1	6759
FBXO11	6698
PSMF1	6659
UBB	6639
PSMC6	6635
FBXW2	6560
PSMD12	6556
SAR1B	6479
AREL1	6465
SEC61A1	6449
KBTBD7	6376
RCHY1	6374
CALR	6340
UBE3C	6282
PSMD11	6231
ASB7	6221
NEDD4	6201
FBXW11	6196
ANAPC11	6161
ITGAV	6106
PSMA6	5970
PSMD7	5963
PSMD13	5948
SEC22B	5873
MGRN1	5794
UBE2Q1	5780
PSMD8	5757
RNF111	5749
SEC13	5748
TIRAP	5640
UBE2V1	5637
FBXL13	5534
CANX	5528
FBXL4	5496
RLIM	5462
IKBKG	5377
PSMA2	5339
VAMP8	5218
KLHL5	5105
UBE2C	5101
KLHL21	5054
UBE2E3	5005
UBE2G1	4921
KEAP1	4898
HERC4	4895
ASB8	4884
HECW2	4860
FBXL20	4844
LRSAM1	4831
UBE2S	4746
SEC61G	4708
FBXO30	4683
UBE2D2	4657
PSMD3	4618
LONRF1	4539
FBXL15	4499
UBC	4439
RNF138	4382
KCTD6	4371
RNF14	4363
SEM1	4348
SKP1	4287
CTSL	4231
PDIA3	4128
UBR2	4099
PSMB2	4084
FBXL8	4021
CDC20	3998
SOCS1	3947
RNF6	3943
RBX1	3934
VHL	3674
SEC24B	3608
FBXO17	3474
UBA6	3438
PSMD5	3426
PSMB1	3374
ASB13	3324
ASB1	3319
FBXL18	3309
MRC1	3109
BLMH	3017
TAPBP	3010
RNF114	2998
UBE3A	2978
CDC26	2923
ANAPC13	2921
UBE2V2	2902
KBTBD6	2724
PSMD14	2611
PSMC2	2598
CUL2	2526
PSMB4	2523
TRIM21	2428
TRIM41	2424
SPSB1	2374
FBXO40	2368
BTBD1	2263
RBCK1	2214
UBE2O	2123
TRIM4	2088
PSMC3	1976
UBE4A	1970
UBE2N	1936
UBE3B	1890
UBE2E2	1779
TRIM9	1746
ASB9	1587
PSMD10	1559
KLHL9	1353
ASB3	1325
ITCH	1318
HECTD3	1201
UBA52	1121
SEC31A	1099
HLA-C	1018
HERC3	1012
FBXL3	1005
CUL5	834
KLHL13	702
ZBTB16	689
HLA-B	649
ZNRF2	633
STX4	606
FBXW5	265
MRC2	-165
PSMA4	-616
CDC27	-651
FBXO41	-657
PSMC5	-863
STUB1	-1032
UBOX5	-1092
RBBP6	-1125
FBXO15	-1269
FBXL12	-1321
GAN	-1414
UBR4	-2086
ASB14	-2170
FZR1	-2233
FBXO6	-2300
UNKL	-2338
HLA-G	-2457
HECTD1	-2490
SEC24C	-2569
HLA-A	-2573
SMURF1	-2591
LTN1	-2597
ASB6	-2763
SIAH1	-3000
CTSV	-3036
PSMB8	-3076
CUL7	-3334
TRIM11	-3671
FBXO22	-3709
HLA-H	-3889
MYLIP	-3991
SPSB2	-4034
KBTBD8	-4224
HLA-E	-4415
UBR1	-4734
LNX1	-4796
BTRC	-4924
ANAPC10	-5000
FBXO27	-5074
SH3RF1	-5151
ANAPC7	-5181
BTBD6	-5202
PSMA3	-5285
ERAP2	-5338
IKBKB	-5386
DTX3L	-5393
ASB4	-5604
PSMB10	-5735
HACE1	-5851
PSMA5	-6053
CDC16	-6071
PSME4	-6087
FBXL14	-6145
RNF34	-6150
KLHL11	-6286
RNF220	-6303
FBXO10	-6427
FBXW7	-6600
ANAPC4	-6644
FBXL16	-6648
ASB16	-6665
TRIM36	-6670
UFL1	-6680
B2M	-6920
RPS27A	-6938
RNF25	-7289
FBXW9	-7360
ERAP1	-7370
ANAPC2	-7407
UBA7	-7558
PSMA8	-7606
LRR1	-7643
HUWE1	-7977
UBE2G2	-8035
SKP2	-8279
UBA5	-8300
FBXO2	-8324
FBXW12	-8358
KLHL42	-8367
TRIM37	-8494
TPP2	-8977
HECTD2	-9020
PSMC4	-9127
DET1	-9199
FBXL22	-9210
CCNF	-9262
HERC1	-9297
THOP1	-9447
TRIM69	-9591
PJA1	-9611
LNPEP	-9618
FBXO44	-9627
LMO7	-9709
RNF115	-9777
PSME1	-9991
FBXW8	-10013
WWP1	-10106
RNF19A	-10197
PSME2	-10336
SMURF2	-10340
TRIM39	-10438
RNF126	-10545
FBXO32	-10607
HERC2	-10658
KLHL25	-10671
UBE3D	-10777
TAP1	-10787
FBXO21	-10790
SEC61A2	-10798
UBE2Z	-10912
ANAPC5	-10967
DZIP3	-11017
MIB2	-11073
GLMN	-11075
HLA-F	-11138
UBE2D4	-11203
UBE2L6	-11293
CDC23	-11304
PSMB9	-11324
CUL1	-11330
KLHL22	-11407
RNF4	-11467
KLHL20	-11483
TRIM32	-11493
KCTD7	-11546
UBE2Q2	-11554
TRAIP	-11615
KLHL3	-11635
FBXW4	-11757
TAP2	-11807
FBXO4	-11843
RNF213	-11905
FBXO31	-11953
ANAPC1	-11962
ASB2	-11978
ARIH2	-12090
MEX3C	-12144
HERC6	-12205
HERC5	-12225
CBLB	-12303

---

Cellular response to hypoxia

Cellular response to hypoxia

	168
set	Cellular response to hypoxia
setSize	72
pANOVA	3.43e-08
s.dist	0.376
p.adjustANOVA	6.61e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UBE2D1	9187
UBE2D3	8640
PSMB7	8485
PSMD4	8402
PSME3	8251
PSMB5	8101
ARNT	8047
EPAS1	7886
PSMD6	7846
PSMD9	7620
ELOC	7519
ELOB	7482
VEGFA	7467
HIF1A	7436
PSMD2	7411
HIGD1A	7394
PSMA1	7329
PSMD1	7241
PSMB3	7171
PSMA7	7096

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UBE2D1	9187
UBE2D3	8640
PSMB7	8485
PSMD4	8402
PSME3	8251
PSMB5	8101
ARNT	8047
EPAS1	7886
PSMD6	7846
PSMD9	7620
ELOC	7519
ELOB	7482
VEGFA	7467
HIF1A	7436
PSMD2	7411
HIGD1A	7394
PSMA1	7329
PSMD1	7241
PSMB3	7171
PSMA7	7096
PSMC1	7021
PSMB6	6813
PSMF1	6659
UBB	6639
PSMC6	6635
EGLN1	6604
PSMD12	6556
CITED2	6457
PSMD11	6231
EP300	6129
PSMA6	5970
PSMD7	5963
PSMD13	5948
PSMD8	5757
PSMA2	5339
UBE2D2	4657
PSMD3	4618
UBC	4439
SEM1	4348
PSMB2	4084
RBX1	3934
VHL	3674
EGLN2	3578
PSMD5	3426
CREBBP	3423
PSMB1	3374
PSMD14	2611
PSMC2	2598
CUL2	2526
PSMB4	2523
PSMC3	1976
PSMD10	1559
UBA52	1121
EGLN3	-437
PSMA4	-616
PSMC5	-863
HIF3A	-2519
PSMB8	-3076
HIF1AN	-4510
PSMA3	-5285
PSMB10	-5735
PSMA5	-6053
PSME4	-6087
RPS27A	-6938
WTIP	-7208
PSMA8	-7606
AJUBA	-7927
PSMC4	-9127
PSME1	-9991
PSME2	-10336
LIMD1	-10791
PSMB9	-11324

---

Detoxification of Reactive Oxygen Species

Detoxification of Reactive Oxygen Species

	279
set	Detoxification of Reactive Oxygen Species
setSize	32
pANOVA	3.64e-08
s.dist	0.562
p.adjustANOVA	6.9e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PRDX3	9366
GPX1	9314
NCF4	9268
GSR	9235
NCF2	9190
CAT	9123
CYBB	9031
ERO1A	8943
PRDX6	8937
PRDX5	8531
P4HB	8440
TXN	8285
TXNRD1	8192
TXNRD2	7526
NCF1	7334
PRDX1	7030
CYBA	6922
TXN2	4651
SOD2	4390
ATOX1	4338

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PRDX3	9366
GPX1	9314
NCF4	9268
GSR	9235
NCF2	9190
CAT	9123
CYBB	9031
ERO1A	8943
PRDX6	8937
PRDX5	8531
P4HB	8440
TXN	8285
TXNRD1	8192
TXNRD2	7526
NCF1	7334
PRDX1	7030
CYBA	6922
TXN2	4651
SOD2	4390
ATOX1	4338
PRDX2	3428
NUDT2	2988
CCS	1538
NOX5	1175
NOX4	1114
ATP7A	694
GPX3	680
GSTP1	135
CYCS	-1334
GPX2	-3533
SOD1	-4862
GPX7	-8901

---

Cargo recognition for clathrin-mediated endocytosis

Cargo recognition for clathrin-mediated endocytosis

	148
set	Cargo recognition for clathrin-mediated endocytosis
setSize	90
pANOVA	4.34e-08
s.dist	0.334
p.adjustANOVA	8.11e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
VAMP7	9499
GRB2	9304
ITSN1	9289
AGFG1	9211
PICALM	9022
CLTC	9000
CLTCL1	8965
TGFA	8889
TGOLN2	8714
AP2M1	8627
ARRB2	8490
CLTA	8376
VAMP3	8222
EGF	8179
REPS2	8154
DAB2	8112
EPN1	8045
TOR1A	8033
AP2S1	8026
FCHO2	7807

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
VAMP7	9499
GRB2	9304
ITSN1	9289
AGFG1	9211
PICALM	9022
CLTC	9000
CLTCL1	8965
TGFA	8889
TGOLN2	8714
AP2M1	8627
ARRB2	8490
CLTA	8376
VAMP3	8222
EGF	8179
REPS2	8154
DAB2	8112
EPN1	8045
TOR1A	8033
AP2S1	8026
FCHO2	7807
SH3GL1	7625
CBL	7480
AP2A2	7257
IGF2R	7149
AP2A1	6832
UBB	6639
GRK3	6593
COPS7A	6590
NEDD8	6482
LDLR	6183
SH3KBP1	6173
STAM2	6159
COPS2	6139
CLTB	6084
GRK2	6068
COPS3	6005
AREG	5977
UBQLN2	5939
SCARB2	5255
VAMP8	5218
UBQLN1	5108
ITSN2	5060
SYT1	5056
HBEGF	5013
HGS	4513
UBC	4439
COPS5	4361
EPS15	4138
EPS15L1	3655
STON2	3569
NECAP2	3387
VAMP4	3191
KIAA0319	3163
EPGN	2662
STON1	2574
CFTR	2416
NECAP1	2220
ARRB1	1998
EREG	1888
COPS4	1776
COPS6	1637
TFRC	1524
LRP2	1307
STAM	1285
UBA52	1121
TF	1102
SYT2	461
AVPR2	291
TOR1B	-2136
FCHO1	-2392
AP2B1	-2709
EPN2	-4100
GPS1	-4517
CD4	-5406
SYT11	-6763
RPS27A	-6938
REPS1	-7137
M6PR	-8519
COPS8	-8755
AAK1	-9190
LDLRAP1	-9326
COPS7B	-9775
IL7R	-10546
DVL2	-11152
CD3D	-11401
CD3G	-11526
FZD4	-11650
SLC2A8	-11749
VAMP2	-11779
ADRB2	-11892

---

Signaling by Nuclear Receptors

Signaling by Nuclear Receptors

	1124
set	Signaling by Nuclear Receptors
setSize	217
pANOVA	5.11e-08
s.dist	0.215
p.adjustANOVA	9.42e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CTSD	9433
H2AJ	9374
GNG10	9349
H2BC21	9283
FKBP5	9091
AGO4	9070
H2BC12	9051
CARM1	9020
MAPK3	8953
ALDH1A2	8914
TGFA	8889
GNG5	8815
FOXO3	8682
H3-3A	8661
ZDHHC7	8636
TLE3	8558
GNB1	8294
SP1	8193
EGF	8179
GNB2	8141

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CTSD	9433.0
H2AJ	9374.0
GNG10	9349.0
H2BC21	9283.0
FKBP5	9091.0
AGO4	9070.0
H2BC12	9051.0
CARM1	9020.0
MAPK3	8953.0
ALDH1A2	8914.0
TGFA	8889.0
GNG5	8815.0
FOXO3	8682.0
H3-3A	8661.0
ZDHHC7	8636.0
TLE3	8558.0
GNB1	8294.0
SP1	8193.0
EGF	8179.0
GNB2	8141.0
GNAI2	8075.0
H2BC5	8003.0
NCOR2	7985.0
GNAI3	7953.0
H2AC6	7934.0
H2BC11	7912.0
KDM4B	7911.0
TBL1X	7887.0
SPHK1	7657.0
TFF3	7621.0
POLR2E	7563.0
RUNX1	7529.0
RXRA	7495.0
MAPK1	7493.0
NR1H2	7415.0
H2BC4	7389.0
PLTP	7338.0
GNB4	7336.0
DLD	7303.0
H2BC17	7285.0
SRF	7079.0
GTF2A2	7066.0
H3C15	6699.5
POLR2J	6671.0
SREBF1	6539.0
GNG11	6495.0
RDH11	6466.0
USF2	6440.0
RARA	6429.0
EEPD1	6251.0
DHRS9	6236.0
PDPK1	6136.0
EP300	6129.0
ABCA1	6109.0
H2AZ1	6036.0
FABP5	6021.0
IGF1R	5990.0
AREG	5977.0
PDK4	5953.0
NCOR1	5887.0
AGO1	5654.0
FOS	5460.0
GTF2F2	5434.0
H2BC9	5394.0
NRAS	5363.0
S1PR3	5323.0
H2BC15	5312.0
POLR2L	5305.0
STAG2	5301.0
CPT1A	5077.0
KDM1B	5073.0
HBEGF	5013.0
PIK3R2	5010.0
H2AC20	4972.0
GTF2F1	4951.0
USF1	4829.0
PPID	4695.0
HDAC3	4673.0
PIK3CA	4629.0
NRIP1	4609.0
POLR2F	4604.0
TBL1XR1	4556.0
CAV2	4516.0
NCOA1	4483.0
PTK2	4462.0
KCTD6	4371.0
GNG8	4296.0
PDHX	4282.0
PDK1	4249.0
PDHB	4233.0
SHC1	4161.0
PTGES3	4125.0
SCD	4026.0
MMP7	3918.0
DHRS4	3786.0
JUN	3722.0
KRAS	3702.0
STRN	3695.0
AKT1	3614.0
NCOA3	3522.0
POLR2G	3508.0
CREBBP	3423.0
GNAI1	3329.0
PDK3	3252.0
ZNF217	3232.0
ABCG8	3056.0
CETP	3003.0
AGO2	2995.0
GTF2A1	2713.0
EPGN	2662.0
MYC	2304.0
ATF2	2085.0
CBFB	2078.0
CAV1	1969.0
EREG	1888.0
RAD21	1709.0
MMP9	1690.0
POLR2C	1616.0
JUND	1549.0
POU2F1	1537.0
FOSB	1368.0
HSP90AA1	1326.0
KAT5	1314.0
NCOA2	1092.0
ELK1	1040.0
GNG3	890.0
FKBP4	832.0
SMC1A	613.0
RDH5	591.0
HDAC1	587.0
YY1	537.0
GNB5	512.0
AKT2	433.0
POLR2I	396.0
MYB	302.0
APOE	218.0
CHD1	69.0
KDM4A	-20.0
APOD	-426.0
FASN	-690.0
GPS2	-889.0
AGO3	-1011.0
XPO1	-1185.0
H2AZ2	-1209.0
CREB1	-1378.0
CRABP2	-1447.0
POLR2K	-1783.0
SMC3	-1975.0
NOS3	-2059.0
CALM1	-2081.0
GNG4	-2154.0
GNB3	-2397.0
KAT2B	-2414.0
POLR2B	-2523.0
POLR2H	-2942.0
POLR2A	-3092.0
RXRB	-3276.0
HRAS	-3382.0
DLAT	-3526.0
NR1H3	-3597.0
PLIN1	-3785.0
UHMK1	-3877.0
CDK9	-3927.0
KANK1	-3964.0
MYLIP	-3991.0
POLR2D	-4024.0
MED1	-4036.0
TNRC6B	-4518.0
PDHA1	-4581.0
CPT1B	-4584.0
RDH10	-4665.0
BCL2	-4704.0
RARG	-5153.0
GNG7	-5198.0
TNRC6A	-5613.0
STAG1	-6347.0
PPARD	-6394.0
ZDHHC21	-6453.0
H2BU1	-6555.0
HSP90AB1	-6863.0
KPNA2	-6910.0
GREB1	-6937.0
CCND1	-6970.0
CXXC5	-7037.0
ALDH8A1	-7123.0
PPP5C	-7462.0
GNG2	-7795.0
ABCG1	-7961.0
PDK2	-8047.0
CDKN1B	-8207.0
RDH16	-8604.0
SRC	-8820.0
ESR1	-9122.0
TBP	-9167.0
PRMT1	-9229.0
ESR2	-9250.0
KDM1A	-9430.0
CCNT1	-9469.0
PIK3R1	-9505.0
DDX5	-9843.0
EBAG9	-10187.0
GPAM	-10241.0
AXIN1	-10285.0
RDH14	-10397.0
RDH13	-10602.0
PRKCZ	-11629.0
ALDH1A1	-11765.0
TNRC6C	-11828.0
AKT3	-11849.0
MOV10	-11991.0
PIK3R3	-12015.0
DHRS3	-12084.0
GNGT2	-12086.0
KDM3A	-12102.0
AKR1C3	-12104.0
GATA3	-12191.0
ARL4C	-12296.0

---

COPII-mediated vesicle transport

COPII-mediated vesicle transport

	135
set	COPII-mediated vesicle transport
setSize	65
pANOVA	5.29e-08
s.dist	0.39
p.adjustANOVA	9.56e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
F5	9485
SERPINA1	9168
RAB1A	9052
CTSZ	8975
TGFA	8889
NSF	8829
RAB1B	8313
SEC24D	8115
TRAPPC1	7806
CNIH1	7779
SEC24A	7660
SEC23A	7335
STX5	7166
TFG	7160
TRAPPC3	7114
MCFD2	7099
LMAN2	7080
F8	7022
LMAN2L	6937
PPP6C	6819

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
F5	9485
SERPINA1	9168
RAB1A	9052
CTSZ	8975
TGFA	8889
NSF	8829
RAB1B	8313
SEC24D	8115
TRAPPC1	7806
CNIH1	7779
SEC24A	7660
SEC23A	7335
STX5	7166
TFG	7160
TRAPPC3	7114
MCFD2	7099
LMAN2	7080
F8	7022
LMAN2L	6937
PPP6C	6819
GORASP1	6606
SAR1B	6479
PREB	6368
COL7A1	6304
GOLGA2	6203
TMED2	6052
AREG	5977
SEC22B	5873
CD59	5859
SEC13	5748
TRAPPC9	5333
PPP6R1	5263
YKT6	5205
TRAPPC5	5191
SEC16A	4619
USO1	4154
TRAPPC6B	4147
NAPG	4139
SEC24B	3608
SCFD1	3525
PPP6R3	3261
CSNK1D	2390
CTSC	2326
NAPA	1432
SEC31A	1099
CNIH2	654
SEC16B	330
TMED10	323
TBC1D20	-18
SEC23IP	-468
BET1	-594
GOSR2	-1456
TRAPPC2L	-2299
SEC24C	-2569
NAPB	-2780
SEC22C	-4248
SEC22A	-5052
ANKRD28	-6250
TRAPPC4	-6712
TRAPPC2	-8704
CNIH3	-9011
TRAPPC10	-9369
LMAN1	-10630
TRAPPC6A	-10917
STX17	-11006

---

RUNX1 regulates transcription of genes involved in differentiation of HSCs

RUNX1 regulates transcription of genes involved in differentiation of HSCs

	929
set	RUNX1 regulates transcription of genes involved in differentiation of HSCs
setSize	83
pANOVA	5.32e-08
s.dist	0.345
p.adjustANOVA	9.56e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AJ	9374
H2BC21	9283
H2BC12	9051
SPI1	8891
H3-3A	8661
PSMB7	8485
GATA1	8410
PSMD4	8402
LMO2	8307
PSME3	8251
PSMB5	8101
H2BC5	8003
H2AC6	7934
H2BC11	7912
PSMD6	7846
PSMD9	7620
RUNX1	7529
PSMD2	7411
H2BC4	7389
PSMA1	7329

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AJ	9374.0
H2BC21	9283.0
H2BC12	9051.0
SPI1	8891.0
H3-3A	8661.0
PSMB7	8485.0
GATA1	8410.0
PSMD4	8402.0
LMO2	8307.0
PSME3	8251.0
PSMB5	8101.0
H2BC5	8003.0
H2AC6	7934.0
H2BC11	7912.0
PSMD6	7846.0
PSMD9	7620.0
RUNX1	7529.0
PSMD2	7411.0
H2BC4	7389.0
PSMA1	7329.0
H2BC17	7285.0
PSMD1	7241.0
PSMB3	7171.0
PSMA7	7096.0
PSMC1	7021.0
PSMB6	6813.0
H3C15	6699.5
PSMF1	6659.0
UBB	6639.0
PSMC6	6635.0
PSMD12	6556.0
TAL1	6518.0
PSMD11	6231.0
H2AZ1	6036.0
PSMA6	5970.0
PSMD7	5963.0
PSMD13	5948.0
PSMD8	5757.0
H2BC9	5394.0
PSMA2	5339.0
H2BC15	5312.0
CDK7	5211.0
H2AC20	4972.0
PSMD3	4618.0
UBC	4439.0
SEM1	4348.0
PSMB2	4084.0
PSMD5	3426.0
PSMB1	3374.0
PSMD14	2611.0
PSMC2	2598.0
PSMB4	2523.0
CBFB	2078.0
PSMC3	1976.0
PSMD10	1559.0
ITCH	1318.0
UBA52	1121.0
CCNH	774.0
MYB	302.0
ABL1	226.0
PSMA4	-616.0
PSMC5	-863.0
H2AZ2	-1209.0
TCF12	-1233.0
PSMB8	-3076.0
TP73	-4754.0
PSMA3	-5285.0
PSMB10	-5735.0
PSMA5	-6053.0
PSME4	-6087.0
H2BU1	-6555.0
RPS27A	-6938.0
TCF3	-7215.0
PSMA8	-7606.0
MNAT1	-8687.0
PSMC4	-9127.0
GATA2	-9800.0
PSME1	-9991.0
LDB1	-10303.0
PSME2	-10336.0
KMT2A	-10725.0
PSMB9	-11324.0
GATA3	-12191.0

---

Cellular responses to stress

Cellular responses to stress

	170
set	Cellular responses to stress
setSize	500
pANOVA	5.6e-08
s.dist	0.142
p.adjustANOVA	9.82e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H1-2	9491
GRB10	9439
LAMTOR1	9411
H2AJ	9374
PRDX3	9366
LMNB1	9345
GPX1	9314
ATP6V1A	9302
H2BC21	9283
NCF4	9268
ATP6V0D1	9245
GSR	9235
NCF2	9190
UBE2D1	9187
DCTN2	9157
ATP6V0C	9127
CAT	9123
MAPK14	9104
FKBP5	9091
AGO4	9070

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H1-2	9491.0
GRB10	9439.0
LAMTOR1	9411.0
H2AJ	9374.0
PRDX3	9366.0
LMNB1	9345.0
GPX1	9314.0
ATP6V1A	9302.0
H2BC21	9283.0
NCF4	9268.0
ATP6V0D1	9245.0
GSR	9235.0
NCF2	9190.0
UBE2D1	9187.0
DCTN2	9157.0
ATP6V0C	9127.0
CAT	9123.0
MAPK14	9104.0
FKBP5	9091.0
AGO4	9070.0
ATP6V1B2	9057.0
H2BC12	9051.0
ATP6V1D	9047.0
YWHAE	9045.0
PHC2	9043.0
CYBB	9031.0
ANAPC15	8968.0
MAPK3	8953.0
ERO1A	8943.0
PRDX6	8937.0
MAP2K6	8887.0
CDKN2B	8836.0
NUP58	8820.0
RRAGD	8753.0
MAP2K3	8748.0
RB1	8707.0
H3-3A	8661.0
UBE2D3	8640.0
E2F2	8601.0
ATP6V0B	8598.0
CAPZA2	8597.0
ATP6V0E1	8596.0
KDM6B	8577.0
ATP6V1C1	8539.0
PRDX5	8531.0
LAMTOR5	8498.0
PSMB7	8485.0
EIF2AK1	8482.0
TFDP1	8470.0
P4HB	8440.0
MAP4K4	8425.0
PSMD4	8402.0
DCTN4	8387.0
MAPKAPK3	8382.0
BAG4	8328.0
TXN	8285.0
PSME3	8251.0
SP1	8193.0
TXNRD1	8192.0
HSBP1	8173.0
CAPZA1	8135.0
PSMB5	8101.0
STAT3	8098.0
ETS2	8092.0
HSPA1A	8071.0
DNAJB6	8066.0
ATP6V1H	8064.0
ARNT	8047.0
ATP6V1E1	8035.0
CAPZB	8015.0
H2BC5	8003.0
CEBPB	7997.0
H2AC6	7934.0
NUP214	7921.0
H2BC11	7912.0
EPAS1	7886.0
AKT1S1	7865.0
CDKN2D	7853.0
PSMD6	7846.0
DYNC1I2	7735.0
DNAJC7	7701.0
RPS6KA1	7695.0
MAP3K5	7682.0
RHEB	7669.0
PSMD9	7620.0
ACTR10	7605.0
LAMTOR3	7574.0
LAMTOR2	7567.0
TXNRD2	7526.0
ELOC	7519.0
MAPK1	7493.0
H1-0	7492.0
ELOB	7482.0
VEGFA	7467.0
HIF1A	7436.0
PSMD2	7411.0
HIGD1A	7394.0
H2BC4	7389.0
BMT2	7350.0
NCF1	7334.0
PSMA1	7329.0
DCTN6	7300.0
H2BC17	7285.0
PSMD1	7241.0
TCIRG1	7188.0
RPL26L1	7176.0
PSMB3	7171.0
PSMA7	7096.0
HSPA2	7081.0
PRDX1	7030.0
HSPA5	7029.0
PSMC1	7021.0
ACTR1A	7002.0
DYNC1LI1	6941.0
CYBA	6922.0
VCP	6886.0
MAP2K4	6866.0
PSMB6	6813.0
CDKN2C	6811.0
UBE2E1	6759.0
EIF2S3	6747.0
H3C15	6699.5
PSMF1	6659.0
E2F3	6650.0
UBB	6639.0
PSMC6	6635.0
GSK3B	6634.0
EGLN1	6604.0
PSMD12	6556.0
IGFBP7	6545.0
HSPA6	6514.0
HSPA1B	6470.0
CITED2	6457.0
BAG1	6396.0
E2F1	6343.0
NFKB1	6277.0
KPTN	6265.0
RRAGA	6244.0
ATF4	6237.0
PSMD11	6231.0
EIF2S2	6175.0
ANAPC11	6161.0
EP300	6129.0
HSF1	6063.0
H2AZ1	6036.0
DCTN3	5994.0
PPP1R15A	5981.0
PSMA6	5970.0
PSMD7	5963.0
DYNLL1	5952.0
PSMD13	5948.0
ATP6V1F	5878.0
PSMD8	5757.0
SEC13	5748.0
ATP6V1E2	5730.0
AGO1	5654.0
FNIP1	5603.0
DNAJA2	5589.0
CEBPG	5466.0
FOS	5460.0
CBX8	5448.0
DNAJA1	5425.0
RPS9	5421.0
H2BC9	5394.0
UBN1	5358.0
HSPA4	5350.0
PSMA2	5339.0
H2BC15	5312.0
RAE1	5164.0
CCNE2	5143.0
UBE2C	5101.0
DCTN1	5078.0
TERF2IP	5040.0
H2AC20	4972.0
RRAGC	4954.0
ID1	4927.0
DDIT3	4906.0
AR	4840.0
UBE2S	4746.0
UBE2D2	4657.0
TXN2	4651.0
PSMD3	4618.0
TINF2	4592.0
NUP50	4521.0
CDKN1A	4511.0
NPRL3	4510.0
RPL3L	4503.0
LAMTOR4	4441.0
UBC	4439.0
ERF	4400.0
SOD2	4390.0
SEM1	4348.0
ATOX1	4338.0
MAPK10	4325.0
MDM2	4312.0
EIF2S1	4279.0
DYNC1LI2	4273.0
DYNC1I1	4187.0
PTGES3	4125.0
PSMB2	4084.0
MAPKAPK2	4054.0
CBX6	4033.0
RBX1	3934.0
ATP6V1G1	3931.0
MAPK11	3826.0
JUN	3722.0
MINK1	3687.0
VHL	3674.0
FLCN	3622.0
EGLN2	3578.0
RNF2	3513.0
PRDX2	3428.0
PSMD5	3426.0
CREBBP	3423.0
MIOS	3378.0
PSMB1	3374.0
DEDD2	3327.0
SESN2	3311.0
HSPA1L	3102.0
NUP98	3101.0
RPS6KA2	3087.0
NUP37	3074.0
VENTX	3057.0
NUDT2	2988.0
RPS6KA3	2973.0
CDC26	2923.0
SLC38A9	2807.0
RPS19BP1	2709.0
PSMD14	2611.0
PSMC2	2598.0
CUL2	2526.0
PSMB4	2523.0
NBN	2267.0
HSPA12B	2254.0
CBX4	2222.0
H1-4	2207.0
MRPL18	2144.0
ATF2	2085.0
RPS27L	2061.0
PSMC3	1976.0
CAMK2G	1921.0
CXCL8	1729.0
CCNA2	1685.0
MAP2K7	1654.0
PSMD10	1559.0
CCS	1538.0
HSP90AA1	1326.0
KAT5	1314.0
NOX5	1175.0
WDR24	1150.0
UBA52	1121.0
NOX4	1114.0
FKBP4	832.0
NUP62	769.0
ATP7A	694.0
GPX3	680.0
CCNA1	585.0
NR3C1	511.0
RPS4Y1	424.0
MLST8	376.0
GSTP1	135.0
HMGA1	117.0
DEPDC5	102.0
EIF2AK4	41.0
RPL36AL	32.0
RPLP1	19.0
HIKESHI	-103.0
RPS24	-263.0
FAU	-362.0
EGLN3	-437.0
PSMA4	-616.0
CDC27	-651.0
RRAGB	-713.0
RANBP2	-820.0
PSMC5	-863.0
DNAJA4	-881.0
RPL15	-963.0
RPLP0	-1000.0
AGO3	-1011.0
HSPA13	-1157.0
RPL8	-1187.0
H2AZ2	-1209.0
MDM4	-1230.0
ST13	-1254.0
CYCS	-1334.0
MAPK7	-1337.0
RPS26	-1430.0
RPL28	-1462.0
RPL22L1	-1619.0
RPS13	-1749.0
HSPA12A	-1760.0
RELA	-1803.0
RBBP4	-1870.0
RPL9	-1872.0
RPL7	-1955.0
RPS8	-2083.0
STIP1	-2094.0
ANAPC16	-2123.0
ATP6V1C2	-2219.0
FZR1	-2233.0
SUZ12	-2409.0
HIF3A	-2519.0
RPL27	-2855.0
FNIP2	-2881.0
HSPA4L	-2948.0
RPL39	-3006.0
NUP85	-3049.0
PSMB8	-3076.0
BAG3	-3170.0
IMPACT	-3210.0
RPL23	-3314.0
RPL6	-3354.0
RPL13	-3431.0
GPX2	-3533.0
RPL4	-3582.0
TERF1	-3601.0
RPL29	-3611.0
RPL7A	-3665.0
RPS15	-3673.0
RPL37A	-3946.0
DYNLL2	-3980.0
RING1	-4063.0
RPS21	-4079.0
DCTN5	-4086.0
SIRT1	-4197.0
POT1	-4355.0
TERF2	-4464.0
RPS2	-4499.0
HIF1AN	-4510.0
TNRC6B	-4518.0
RPL31	-4541.0
CBX2	-4617.0
RPS16	-4669.0
RPS3A	-4694.0
RPS28	-4713.0
RPL5	-4728.0
RPL22	-4740.0
SOD1	-4862.0
BAG5	-4887.0
DNAJC2	-4961.0
RPS7	-4968.0
ANAPC10	-5000.0
CDK2	-5006.0
RPL18	-5080.0
EEF1A1	-5087.0
ANAPC7	-5181.0
CDKN2A	-5236.0
PSMA3	-5285.0
RPL36	-5287.0
ATF5	-5305.0
SZT2	-5322.0
RPL17	-5431.0
RPS14	-5463.0
NUP42	-5564.0
TNRC6A	-5613.0
DNAJB1	-5672.0
RPS5	-5691.0
PSMB10	-5735.0
RPS15A	-5742.0
RPS10	-5793.0
RPL24	-5799.0
SCMH1	-5839.0
RPL38	-5840.0
TRIB3	-5843.0
RPS3	-5914.0
RPS12	-5987.0
RPL35A	-6015.0
PSMA5	-6053.0
SEH1L	-6069.0
RPL18A	-6070.0
CDC16	-6071.0
PSME4	-6087.0
RPS6	-6160.0
RPS17	-6247.0
RPL27A	-6257.0
RPL11	-6261.0
RPL19	-6281.0
RPS4X	-6285.0
RPS23	-6292.0
RPA2	-6306.0
NUP153	-6321.0
RPSA	-6323.0
RPS25	-6365.0
RPL37	-6375.0
RPL21	-6458.0
CDK6	-6465.0
RLN1	-6482.0
RPL10	-6534.0
EP400	-6550.0
H2BU1	-6555.0
RPL26	-6612.0
ANAPC4	-6644.0
RPL10A	-6686.0
RPL32	-6709.0
RPL14	-6710.0
RPL34	-6802.0
HSP90AB1	-6863.0
RPL41	-6866.0
RPS27A	-6938.0
RPS19	-6965.0
RPL30	-7020.0
TPR	-7028.0
RPL12	-7053.0
MAPK9	-7068.0
RPLP2	-7087.0
POM121C	-7188.0
WTIP	-7208.0
RPS11	-7243.0
RAD50	-7373.0
RPL36A	-7376.0
ANAPC2	-7407.0
PSMA8	-7606.0
DYNC1H1	-7685.0
RPS18	-7744.0
NUP133	-7762.0
ACD	-7800.0
MRE11	-7923.0
AJUBA	-7927.0
RPS29	-7940.0
BAG2	-7997.0
RPL35	-8092.0
PHC3	-8152.0
CDKN1B	-8207.0
RPL13A	-8212.0
HSPA7	-8236.0
POM121	-8299.0
ASNS	-8316.0
HDAC6	-8337.0
MAPKAPK5	-8364.0
AAAS	-8389.0
PHC1	-8402.0
NUP54	-8479.0
EHMT2	-8558.0
RPL3	-8561.0
EHMT1	-8692.0
RPL39L	-8805.0
SH3BP4	-8881.0
RPS20	-8886.0
GPX7	-8901.0
RPA3	-8911.0
SESN1	-8962.0
PSMC4	-9127.0
WDR59	-9240.0
EED	-9348.0
HSPA14	-9380.0
HSPH1	-9407.0
MAPK8	-9428.0
ATP6V1G2	-9515.0
NUP43	-9517.0
RPL23A	-9567.0
HIRA	-9628.0
ATF3	-9677.0
EZH2	-9741.0
RPS27	-9756.0
MTOR	-9767.0
HSPA9	-9780.0
ASF1A	-9781.0
BMI1	-9829.0
PSME1	-9991.0
SERPINH1	-10121.0
CCAR2	-10156.0
NUP155	-10233.0
PSME2	-10336.0
ATR	-10354.0
GCN1	-10372.0
NUP107	-10421.0
RPTOR	-10464.0
NUP160	-10557.0
CABIN1	-10590.0
NUP35	-10611.0
NR3C2	-10625.0
ITFG2	-10719.0
NUP210	-10726.0
LIMD1	-10791.0
TP53	-10893.0
HSPA8	-10922.0
C12orf66	-10960.0
ANAPC5	-10967.0
ATM	-11148.0
CDK4	-11256.0
CDC23	-11304.0
NUP205	-11321.0
PSMB9	-11324.0
ETS1	-11386.0
NUP88	-11397.0
ATP6V0E2	-11555.0
NPRL2	-11604.0
NUP93	-11620.0
NUP188	-11624.0
TNIK	-11674.0
CCNE1	-11707.0
CAMK2D	-11816.0
TNRC6C	-11828.0
ANAPC1	-11962.0
MOV10	-11991.0
RPA1	-12004.0
RBBP7	-12155.0
NDC1	-12173.0
TNFRSF21	-12254.0
TFDP2	-12364.0

---

The citric acid (TCA) cycle and respiratory electron transport

The citric acid (TCA) cycle and respiratory electron transport

	1230
set	The citric acid (TCA) cycle and respiratory electron transport
setSize	172
pANOVA	5.61e-08
s.dist	0.24
p.adjustANOVA	9.82e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BSG	9172
ME1	8892
SLC16A3	8783
ETFA	8658
LDHA	8637
NDUFB3	8430
SDHC	8390
NDUFB9	8237
NDUFAF1	8167
UQCRH	8073
ETFDH	8052
UQCRC1	7859
COX7A2L	7719
ETFB	7688
ATP5PD	7637
SDHB	7587
NDUFB1	7578
SUCLA2	7558
ATP5PB	7551
RXRA	7495

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BSG	9172
ME1	8892
SLC16A3	8783
ETFA	8658
LDHA	8637
NDUFB3	8430
SDHC	8390
NDUFB9	8237
NDUFAF1	8167
UQCRH	8073
ETFDH	8052
UQCRC1	7859
COX7A2L	7719
ETFB	7688
ATP5PD	7637
SDHB	7587
NDUFB1	7578
SUCLA2	7558
ATP5PB	7551
RXRA	7495
DLD	7303
NDUFAF3	6981
SDHD	6963
ME2	6915
UQCR11	6907
TIMMDC1	6822
ATP5F1C	6687
COX8A	6611
ATP5MF	6519
ATP5F1B	6497
NDUFA4	6459
ATP5F1A	6441
ATP5PF	6373
NDUFS1	6348
UQCRFS1	6325
COX5B	6207
NDUFS5	6178
COX5A	6168
ATP5F1E	6142
NDUFC2	6093
NDUFS2	6080
NDUFA6	6009
SUCLG1	5961
PDK4	5953
ATP5MC3	5906
UQCRC2	5852
NDUFB10	5812
NDUFAB1	5759
NDUFA1	5718
COX6B1	5667
NDUFA7	5623
ATP5MG	5512
GSTZ1	5438
NDUFC1	5343
NDUFV3	5214
HAGH	5104
COX6A1	5095
NDUFA2	4966
ECSIT	4918
NDUFA8	4804
ATP5PO	4794
MPC2	4555
NDUFB4	4553
COX7B	4465
SLC16A1	4455
NNT	4407
TACO1	4406
UQCR10	4378
VDAC1	4347
NDUFV2	4288
PDHX	4282
PDK1	4249
NDUFA13	4244
PDHB	4233
NDUFB6	4218
ACO2	4209
MDH2	4207
COX4I1	4191
NDUFS6	4155
OGDH	4136
COQ10B	3989
NDUFS4	3986
NDUFB5	3892
UQCRB	3834
CS	3688
SURF1	3532
IDH3G	3314
PDK3	3252
CYC1	3047
ATP5F1D	2968
UQCRQ	2960
ATP5MC2	2956
FH	2879
NDUFAF7	2726
ATP5ME	2664
NDUFB7	2292
NDUFAF2	2133
NDUFS7	2118
SLC16A8	1608
NDUFA11	1458
NDUFB11	1172
NDUFB8	965
UCP2	913
NDUFS3	884
MT-ND4	840
COX6C	706
MT-CO1	684
COX7C	564
NDUFA3	503
MT-ND6	459
FAHD1	174
COX16	132
NDUFS8	81
MT-CO2	48
MT-CO3	40
ACAD9	-879
MPC1	-1097
CYCS	-1334
COX14	-1496
IDH3B	-1504
NDUFA12	-1728
MT-ATP6	-2096
MT-ND5	-2166
MT-CYB	-2254
NDUFAF6	-2331
LDHAL6A	-2551
MT-ATP8	-3067
IDH2	-3102
DLAT	-3526
MT-ND1	-3616
MT-ND3	-3649
GLO1	-3721
PDP1	-4260
SCO2	-4351
SLC25A27	-4356
NDUFB2	-4446
PDHA1	-4581
SLC25A14	-4642
NDUFA5	-4723
COX20	-5018
ADHFE1	-5216
SDHA	-5579
D2HGDH	-5760
SUCLG2	-5783
COX18	-6126
PPARD	-6394
MT-ND2	-6560
COX19	-6882
NDUFA10	-6994
DMAC2L	-7274
PDPR	-7326
ATP5MC1	-7616
PDK2	-8047
TMEM126B	-8346
NDUFA9	-8864
DLST	-8906
IDH3A	-9280
NDUFAF5	-9499
SCO1	-9819
L2HGDH	-9902
PM20D1	-9905
LDHB	-9933
ME3	-10048
NDUFAF4	-10063
LRPPRC	-10081
UCP3	-10214
TRAP1	-10796
PDP2	-11231
COQ10A	-11405
NDUFV1	-11466
COX11	-11539
NUBPL	-11628

---

trans-Golgi Network Vesicle Budding

trans-Golgi Network Vesicle Budding

	1365
set	trans-Golgi Network Vesicle Budding
setSize	69
pANOVA	9.29e-08
s.dist	0.372
p.adjustANOVA	1.61e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
VAMP7	9499
GNS	9360
AP1S1	9286
APP	9177
SORT1	9171
ARF1	9064
PICALM	9022
CLTC	9000
CTSZ	8975
CPD	8824
CHMP2A	8780
AP1B1	8730
TGOLN2	8714
FTL	8665
RAB5C	8655
BLOC1S1	8630
SNAP23	8628
CLTA	8376
AP3B1	8365
AP3S1	7874

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
VAMP7	9499
GNS	9360
AP1S1	9286
APP	9177
SORT1	9171
ARF1	9064
PICALM	9022
CLTC	9000
CTSZ	8975
CPD	8824
CHMP2A	8780
AP1B1	8730
TGOLN2	8714
FTL	8665
RAB5C	8655
BLOC1S1	8630
SNAP23	8628
CLTA	8376
AP3B1	8365
AP3S1	7874
SNX2	7861
SNAPIN	7443
IGF2R	7149
BLOC1S6	6815
DNASE2	6745
AP1M1	6711
OCRL	6442
AP4E1	6419
DNM2	6089
CLTB	6084
YIPF6	5857
ACBD3	5816
VAMP8	5218
FTH1	4902
DNAJC6	4640
HGS	4513
AP1G1	3987
CLINT1	3815
PUM1	3250
GAK	2570
NECAP1	2220
ARRB1	1998
AP1M2	1832
TFRC	1524
NAPA	1432
TBC1D8B	1417
DTNBP1	1014
STX4	606
TXNDC5	393
AP4M1	138
SNX9	-430
AP1S2	-2261
SNX5	-3305
TPD52L1	-3542
SH3D19	-4011
GBF1	-4290
PIK3C2A	-5194
GOLGB1	-5370
AP1S3	-5522
AP1G2	-5590
AP4S1	-5731
AP4B1	-7235
BLOC1S4	-7493
M6PR	-8519
BLOC1S3	-8703
TPD52	-9644
HIP1R	-10615
HSPA8	-10922
VAMP2	-11779

---

ESR-mediated signaling

ESR-mediated signaling

	334
set	ESR-mediated signaling
setSize	161
pANOVA	1.07e-07
s.dist	0.243
p.adjustANOVA	1.83e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CTSD	9433
H2AJ	9374
GNG10	9349
H2BC21	9283
FKBP5	9091
AGO4	9070
H2BC12	9051
CARM1	9020
MAPK3	8953
TGFA	8889
GNG5	8815
FOXO3	8682
H3-3A	8661
ZDHHC7	8636
TLE3	8558
GNB1	8294
SP1	8193
EGF	8179
GNB2	8141
GNAI2	8075

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CTSD	9433.0
H2AJ	9374.0
GNG10	9349.0
H2BC21	9283.0
FKBP5	9091.0
AGO4	9070.0
H2BC12	9051.0
CARM1	9020.0
MAPK3	8953.0
TGFA	8889.0
GNG5	8815.0
FOXO3	8682.0
H3-3A	8661.0
ZDHHC7	8636.0
TLE3	8558.0
GNB1	8294.0
SP1	8193.0
EGF	8179.0
GNB2	8141.0
GNAI2	8075.0
H2BC5	8003.0
GNAI3	7953.0
H2AC6	7934.0
H2BC11	7912.0
KDM4B	7911.0
SPHK1	7657.0
TFF3	7621.0
POLR2E	7563.0
RUNX1	7529.0
MAPK1	7493.0
H2BC4	7389.0
GNB4	7336.0
H2BC17	7285.0
SRF	7079.0
GTF2A2	7066.0
H3C15	6699.5
POLR2J	6671.0
GNG11	6495.0
USF2	6440.0
PDPK1	6136.0
EP300	6129.0
H2AZ1	6036.0
IGF1R	5990.0
AREG	5977.0
AGO1	5654.0
FOS	5460.0
GTF2F2	5434.0
H2BC9	5394.0
NRAS	5363.0
S1PR3	5323.0
H2BC15	5312.0
POLR2L	5305.0
STAG2	5301.0
HBEGF	5013.0
PIK3R2	5010.0
H2AC20	4972.0
GTF2F1	4951.0
USF1	4829.0
PPID	4695.0
PIK3CA	4629.0
NRIP1	4609.0
POLR2F	4604.0
CAV2	4516.0
NCOA1	4483.0
PTK2	4462.0
KCTD6	4371.0
GNG8	4296.0
SHC1	4161.0
PTGES3	4125.0
MMP7	3918.0
JUN	3722.0
KRAS	3702.0
STRN	3695.0
AKT1	3614.0
NCOA3	3522.0
POLR2G	3508.0
CREBBP	3423.0
GNAI1	3329.0
ZNF217	3232.0
AGO2	2995.0
GTF2A1	2713.0
EPGN	2662.0
MYC	2304.0
ATF2	2085.0
CBFB	2078.0
CAV1	1969.0
EREG	1888.0
RAD21	1709.0
MMP9	1690.0
POLR2C	1616.0
JUND	1549.0
POU2F1	1537.0
FOSB	1368.0
HSP90AA1	1326.0
KAT5	1314.0
NCOA2	1092.0
ELK1	1040.0
GNG3	890.0
FKBP4	832.0
SMC1A	613.0
HDAC1	587.0
YY1	537.0
GNB5	512.0
AKT2	433.0
POLR2I	396.0
MYB	302.0
CHD1	69.0
AGO3	-1011.0
XPO1	-1185.0
H2AZ2	-1209.0
CREB1	-1378.0
POLR2K	-1783.0
SMC3	-1975.0
NOS3	-2059.0
CALM1	-2081.0
GNG4	-2154.0
GNB3	-2397.0
KAT2B	-2414.0
POLR2B	-2523.0
POLR2H	-2942.0
POLR2A	-3092.0
HRAS	-3382.0
UHMK1	-3877.0
CDK9	-3927.0
KANK1	-3964.0
POLR2D	-4024.0
MED1	-4036.0
TNRC6B	-4518.0
BCL2	-4704.0
GNG7	-5198.0
TNRC6A	-5613.0
STAG1	-6347.0
ZDHHC21	-6453.0
H2BU1	-6555.0
HSP90AB1	-6863.0
KPNA2	-6910.0
GREB1	-6937.0
CCND1	-6970.0
CXXC5	-7037.0
PPP5C	-7462.0
GNG2	-7795.0
CDKN1B	-8207.0
SRC	-8820.0
ESR1	-9122.0
TBP	-9167.0
PRMT1	-9229.0
ESR2	-9250.0
KDM1A	-9430.0
CCNT1	-9469.0
PIK3R1	-9505.0
DDX5	-9843.0
EBAG9	-10187.0
GPAM	-10241.0
AXIN1	-10285.0
PRKCZ	-11629.0
TNRC6C	-11828.0
AKT3	-11849.0
MOV10	-11991.0
PIK3R3	-12015.0
GNGT2	-12086.0
GATA3	-12191.0

---

PD-1 signaling

PD-1 signaling

	780
set	PD-1 signaling
setSize	28
pANOVA	1.11e-07
s.dist	-0.579
p.adjustANOVA	1.87e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CD247	-12345
HLA-DPA1	-12316
HLA-DPB1	-12248
HLA-DRA	-12009
TRBC1	-12006
HLA-DQA1	-11992
LCK	-11838
CD3G	-11526
TRAC	-11482
CD3D	-11401
CD3E	-11302
TRBV12-3	-10436
TRAV19	-9915
TRAV29DV5	-9673
TRBV7-9	-9539
HLA-DQB2	-9401
HLA-DRB1	-8075
CD274	-7563
TRAV8-4	-7261
PDCD1	-6792

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CD247	-12345
HLA-DPA1	-12316
HLA-DPB1	-12248
HLA-DRA	-12009
TRBC1	-12006
HLA-DQA1	-11992
LCK	-11838
CD3G	-11526
TRAC	-11482
CD3D	-11401
CD3E	-11302
TRBV12-3	-10436
TRAV19	-9915
TRAV29DV5	-9673
TRBV7-9	-9539
HLA-DQB2	-9401
HLA-DRB1	-8075
CD274	-7563
TRAV8-4	-7261
PDCD1	-6792
HLA-DQB1	-6416
CD4	-5406
HLA-DRB5	-4971
HLA-DQA2	-4806
PDCD1LG2	-3326
CSK	5219
PTPN11	5314
PTPN6	6096

---

rRNA modification in the nucleus and cytosol

rRNA modification in the nucleus and cytosol

	1355
set	rRNA modification in the nucleus and cytosol
setSize	59
pANOVA	1.39e-07
s.dist	-0.396
p.adjustANOVA	2.32e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NAT10	-11952
NOP56	-11750
BMS1	-11670
DKC1	-11637
PDCD11	-11518
UTP4	-11494
DDX47	-11299
IMP4	-10976
WDR46	-10970
NOL6	-10908
NOP14	-10866
UTP15	-10603
UTP20	-10529
NOL11	-10471
HEATR1	-10345
EMG1	-10189
FBL	-10188
RRP9	-10080
NOP2	-9952
NOP58	-9951

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NAT10	-11952
NOP56	-11750
BMS1	-11670
DKC1	-11637
PDCD11	-11518
UTP4	-11494
DDX47	-11299
IMP4	-10976
WDR46	-10970
NOL6	-10908
NOP14	-10866
UTP15	-10603
UTP20	-10529
NOL11	-10471
HEATR1	-10345
EMG1	-10189
FBL	-10188
RRP9	-10080
NOP2	-9952
NOP58	-9951
WDR75	-9921
THUMPD1	-9802
IMP3	-9459
KRR1	-8623
DHX37	-8267
DIMT1	-7988
MPHOSPH10	-7790
WDR43	-7687
GAR1	-6941
SNU13	-6871
PNO1	-6861
WDR3	-6619
RPS6	-6160
DCAF13	-5572
NOC4L	-5483
RPS14	-5463
RPS7	-4968
UTP6	-4507
RPS2	-4499
WDR36	-3945
NHP2	-3471
TBL3	-3437
UTP3	-2903
RRP7A	-2806
SNORD3A	-2539
UTP14C	-2073
UTP14A	-1821
RRP36	-1672
PWP2	-1207
RCL1	-757
DDX52	454
TRMT112	738
TSR3	3846
FCF1	4472
UTP11	4631
DDX49	4872
UTP18	5114
RPS9	5421
NOP10	8332

---

RAB GEFs exchange GTP for GDP on RABs

RAB GEFs exchange GTP for GDP on RABs

	879
set	RAB GEFs exchange GTP for GDP on RABs
setSize	88
pANOVA	1.51e-07
s.dist	0.324
p.adjustANOVA	2.49e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RAB32	9463
RAB13	9440
RAB31	9356
SBF2	9078
RAB1A	9052
YWHAE	9045
RAB3IL1	9005
RAB10	8926
RAB7A	8742
RAB5C	8655
RAB27A	8411
RIN2	8355
RAB1B	8313
RAB6A	8148
RAB3A	8133
DENND3	7938
TRAPPC1	7806
RAB18	7801
DENND5A	7736
RIN1	7602

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RAB32	9463
RAB13	9440
RAB31	9356
SBF2	9078
RAB1A	9052
YWHAE	9045
RAB3IL1	9005
RAB10	8926
RAB7A	8742
RAB5C	8655
RAB27A	8411
RIN2	8355
RAB1B	8313
RAB6A	8148
RAB3A	8133
DENND3	7938
TRAPPC1	7806
RAB18	7801
DENND5A	7736
RIN1	7602
RABGEF1	7466
DENND1A	7441
GDI2	7282
ULK1	7125
TRAPPC3	7114
RAB39A	7113
RAB5A	7103
RAB14	7095
RIC1	6824
GAPVD1	6799
TRAPPC8	6735
RAB5B	6690
MON1B	6612
RAB8B	6529
TRAPPC12	6310
RAB21	6165
RAB6B	6053
DENND2C	5898
RAB3GAP1	5768
GDI1	5739
HPS1	5605
TRAPPC9	5333
TRAPPC11	5319
TRAPPC5	5191
RGP1	4538
RAB3GAP2	4429
CCZ1	4242
TRAPPC6B	4147
RAB9A	4088
RAB35	3981
RAB8A	3880
AKT1	3614
RAB27B	3386
RAB3IP	3237
ALS2	3176
DENND4B	3139
DENND6B	2993
CHM	2273
CCZ1B	990
AKT2	433
ANKRD27	186
DENND6A	-562
RAB12	-856
CHML	-1515
RAB7B	-1531
TRAPPC2L	-2299
TRAPPC13	-2479
MON1A	-2910
DENND5B	-4249
DENND4A	-5540
RAB9B	-6552
TRAPPC4	-6712
DENND1C	-7377
DENND4C	-7574
ALS2CL	-8315
DENND2A	-8355
TRAPPC2	-8704
RAB38	-8714
DENND1B	-9284
TRAPPC10	-9369
RINL	-10326
SBF1	-10530
TRAPPC6A	-10917
RAB39B	-11529
HPS4	-11558
AKT3	-11849
MADD	-11899
DENND2D	-12293

---

Rab regulation of trafficking

Rab regulation of trafficking

	934
set	Rab regulation of trafficking
setSize	121
pANOVA	1.59e-07
s.dist	0.276
p.adjustANOVA	2.59e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RAB32	9463
RAB13	9440
RAB31	9356
TBC1D2	9301
SBF2	9078
RAB1A	9052
YWHAE	9045
GABARAPL2	9044
RAB3IL1	9005
RAB10	8926
TBC1D14	8897
RAB7A	8742
RAB11A	8688
RAB5C	8655
RAB27A	8411
RIN2	8355
RAB1B	8313
RAB6A	8148
RAB3A	8133
TBC1D10B	8078

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RAB32	9463
RAB13	9440
RAB31	9356
TBC1D2	9301
SBF2	9078
RAB1A	9052
YWHAE	9045
GABARAPL2	9044
RAB3IL1	9005
RAB10	8926
TBC1D14	8897
RAB7A	8742
RAB11A	8688
RAB5C	8655
RAB27A	8411
RIN2	8355
RAB1B	8313
RAB6A	8148
RAB3A	8133
TBC1D10B	8078
MAP1LC3B	8043
RAB4A	7941
DENND3	7938
GABARAP	7904
TRAPPC1	7806
RAB18	7801
DENND5A	7736
RIN1	7602
RABGEF1	7466
DENND1A	7441
GDI2	7282
RAB33B	7267
ULK1	7125
TRAPPC3	7114
RAB39A	7113
RAB5A	7103
RAB14	7095
RIC1	6824
GAPVD1	6799
TRAPPC8	6735
RAB5B	6690
MON1B	6612
RAB8B	6529
TBC1D7	6452
TRAPPC12	6310
RAB21	6165
RAB6B	6053
DENND2C	5898
RAB3GAP1	5768
GDI1	5739
HPS1	5605
TRAPPC9	5333
TRAPPC11	5319
TRAPPC5	5191
RGP1	4538
RAB3GAP2	4429
RAB11B	4402
CCZ1	4242
TRAPPC6B	4147
RAB9A	4088
RAB35	3981
RAB8A	3880
GGA3	3816
TBC1D13	3782
TBC1D15	3665
AKT1	3614
TBC1D16	3409
RAB27B	3386
RAB3IP	3237
TBC1D24	3200
ALS2	3176
DENND4B	3139
DENND6B	2993
GGA1	2310
CHM	2273
RABGAP1	2052
ARF6	1377
CCZ1B	990
AKT2	433
ANKRD27	186
TBC1D20	-18
TBC1D3	-66
DENND6A	-562
TSC2	-804
RAB12	-856
CHML	-1515
RAB7B	-1531
TSC1	-2118
TRAPPC2L	-2299
TRAPPC13	-2479
MON1A	-2910
DENND5B	-4249
DENND4A	-5540
RAB9B	-6552
GGA2	-6587
TRAPPC4	-6712
TBC1D25	-7372
DENND1C	-7377
DENND4C	-7574
ALS2CL	-8315
DENND2A	-8355
TRAPPC2	-8704
RAB38	-8714
TBC1D17	-8716
DENND1B	-9284
TRAPPC10	-9369
POLG	-9889
SYTL1	-10104
RINL	-10326
SBF1	-10530
TRAPPC6A	-10917
RAB33A	-10940
RAB39B	-11529
HPS4	-11558
RABEP1	-11754
OPTN	-11766
AKT3	-11849
TBC1D10C	-11861
MADD	-11899
TBC1D10A	-12025
DENND2D	-12293

---

MAP2K and MAPK activation

MAP2K and MAPK activation

	612
set	MAP2K and MAPK activation
setSize	34
pANOVA	1.81e-07
s.dist	0.517
p.adjustANOVA	2.91e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MAP2K1	9063
MAPK3	8953
ITGA2B	8893
APBB1IP	8744
MARK3	8697
TLN1	8525
ARRB2	8490
ITGB3	8291
FN1	8284
IQGAP1	8152
RAF1	7879
LAMTOR3	7574
LAMTOR2	7567
MAPK1	7493
VCL	7328
RAP1A	7305
MAP2K2	6794
VWF	6641
YWHAB	6385
NRAS	5363

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MAP2K1	9063
MAPK3	8953
ITGA2B	8893
APBB1IP	8744
MARK3	8697
TLN1	8525
ARRB2	8490
ITGB3	8291
FN1	8284
IQGAP1	8152
RAF1	7879
LAMTOR3	7574
LAMTOR2	7567
MAPK1	7493
VCL	7328
RAP1A	7305
MAP2K2	6794
VWF	6641
YWHAB	6385
NRAS	5363
CSK	5219
KSR1	4167
WDR83	3718
KRAS	3702
RAP1B	3206
ARAF	2644
ARRB1	1998
BRAF	1308
KSR2	-3361
HRAS	-3382
CNKSR2	-4781
CNKSR1	-7089
SRC	-8820
PEBP1	-11270

---

tRNA processing

tRNA processing

	1362
set	tRNA processing
setSize	136
pANOVA	2.88e-07
s.dist	-0.255
p.adjustANOVA	4.58e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MT-TP	-12349
TSEN54	-12272
NDC1	-12173
TP53RK	-12040
THADA	-11763
ELAC2	-11761
NUP188	-11624
NUP93	-11620
ALKBH8	-11614
NUP88	-11397
NUP205	-11321
TRMT11	-11243
TSEN2	-10933
NUP210	-10726
LCMT2	-10707
NUP35	-10611
NUP160	-10557
THG1L	-10487
NUP107	-10421
NUP155	-10233

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MT-TP	-12349
TSEN54	-12272
NDC1	-12173
TP53RK	-12040
THADA	-11763
ELAC2	-11761
NUP188	-11624
NUP93	-11620
ALKBH8	-11614
NUP88	-11397
NUP205	-11321
TRMT11	-11243
TSEN2	-10933
NUP210	-10726
LCMT2	-10707
NUP35	-10611
NUP160	-10557
THG1L	-10487
NUP107	-10421
NUP155	-10233
WDR4	-10005
TRMT13	-9983
ADAT2	-9944
TSEN15	-9901
POP5	-9676
QTRT1	-9595
TRMT61A	-9554
NUP43	-9517
CPSF4	-9416
TRMU	-9261
TYW1	-9203
ADAT1	-9178
CDKAL1	-9175
CTU2	-8961
FTSJ1	-8550
NUP54	-8479
AAAS	-8389
MTO1	-8384
TYW3	-8331
POM121	-8299
RPP25	-8247
FAM98B	-8222
RPP30	-8101
TRMT61B	-7979
NUP133	-7762
NSUN6	-7729
TRNT1	-7551
GTPBP3	-7252
POM121C	-7188
MT-TL2	-7170
METTL1	-7148
RPP38	-7076
TPR	-7028
TRMT44	-6885
OSGEP	-6794
RAN	-6791
MT-TE	-6588
MT-ND2	-6560
CSTF2	-6444
PUS1	-6392
NUP153	-6321
SEH1L	-6069
C2orf49	-5807
NUP42	-5564
PUS7	-5462
MT-TY	-5442
RPP21	-5355
TPRKB	-5218
RPP40	-4835
MT-TN	-4771
MT-TC	-4522
TRMT10C	-4481
POP1	-4049
MT-TA	-3981
CPSF1	-3813
POP4	-3797
MT-TV	-3652
MT-ND3	-3649
MT-ND1	-3616
TRMT1	-3444
EPRS1	-3185
MT-ATP8	-3067
NUP85	-3049
MT-TL1	-2976
MT-TS1	-2975
DDX1	-2786
MT-TF	-2754
XPOT	-2715
MT-CYB	-2254
MT-ND5	-2166
MT-ATP6	-2096
MT-ND4L	-2023
NSUN2	-1892
LAGE3	-1809
MT-TM	-1516
RTCB	-1471
TYW5	-1212
URM1	-1142
RANBP2	-820
TRMT12	-321
MT-RNR1	-300
MT-CO3	40
MT-CO2	48
RPPH1	88
MT-ND6	459
MT-CO1	684
TRMT112	738
TRIT1	758
NUP62	769
MT-ND4	840
TRDMT1	912
ADAT3	1101
TRMT5	1218
MT-RNR2	2112
QTRT2	2329
RPP14	3005
NUP37	3074
NUP98	3101
PRORP	3390
DUS2	3467
PUS3	3643
POP7	4149
RTRAF	4178
HSD17B10	4182
ZBTB8OS	4258
NUP50	4521
CTU1	4623
RAE1	5164
TRMT6	5698
SEC13	5748
CLP1	6589
TRMT10A	6869
TSEN34	7508
TRMT9B	7722
NUP214	7921
NUP58	8820

---

Post-translational protein phosphorylation

Post-translational protein phosphorylation

	843
set	Post-translational protein phosphorylation
setSize	70
pANOVA	2.94e-07
s.dist	0.354
p.adjustANOVA	4.62e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FAM20A	9524
VCAN	9505
F5	9485
FAM20C	9421
LAMC1	9387
CKAP4	9370
APLP2	9347
QSOX1	9298
FSTL3	9290
PCSK9	9208
APP	9177
SERPINA1	9168
LGALS1	9032
PNPLA2	8939
NUCB1	8883
ADAM10	8791
TGOLN2	8714
TIMP1	8677
P4HB	8440
DNAJC3	8435

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FAM20A	9524
VCAN	9505
F5	9485
FAM20C	9421
LAMC1	9387
CKAP4	9370
APLP2	9347
QSOX1	9298
FSTL3	9290
PCSK9	9208
APP	9177
SERPINA1	9168
LGALS1	9032
PNPLA2	8939
NUCB1	8883
ADAM10	8791
TGOLN2	8714
TIMP1	8677
P4HB	8440
DNAJC3	8435
FUCA2	8304
FN1	8284
GAS6	8063
LTBP1	7962
FSTL1	7908
CALU	7894
MELTF	7197
IGFBP7	6545
ANO8	6099
LAMB1	5966
PDIA6	5882
APOA2	5879
SDC2	5397
TMEM132A	5245
PRKCSH	5220
FBN1	4836
C4A	4466
SERPINA10	3902
ALB	3668
MFGE8	3534
KTN1	3363
MBTPS1	2966
CST3	2206
HSP90B1	2059
SHISA5	1269
TF	1102
LAMB2	501
APOE	218
CP	-1561
CSF1	-2061
MSLN	-2192
ENAM	-2373
SERPIND1	-2722
TNC	-4039
BMP4	-4081
MGAT4A	-5680
MIA3	-6245
FGF23	-6622
ITIH2	-6820
GOLM1	-6842
MXRA8	-7477
IGFBP4	-7582
APOL1	-7657
MEN1	-8538
IGFBP3	-9455
WFS1	-9774
PROC	-10098
RCN1	-10766
C3	-12262
PRSS23	-12288

---

CLEC7A (Dectin-1) signaling

CLEC7A (Dectin-1) signaling

	131
set	CLEC7A (Dectin-1) signaling
setSize	97
pANOVA	3.16e-07
s.dist	0.3
p.adjustANOVA	4.91e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UBE2D1	9187
SYK	9076
PRKCD	9008
PYCARD	8638
CDC34	8611
PSMB7	8485
PSMD4	8402
PSME3	8251
PPP3R1	8175
PSMB5	8101
CHUK	7966
PSMD6	7846
UBA3	7767
PSMD9	7620
UBE2M	7477
PSMD2	7411
PSMA1	7329
PSMD1	7241
PSMB3	7171
PSMA7	7096

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UBE2D1	9187
SYK	9076
PRKCD	9008
PYCARD	8638
CDC34	8611
PSMB7	8485
PSMD4	8402
PSME3	8251
PPP3R1	8175
PSMB5	8101
CHUK	7966
PSMD6	7846
UBA3	7767
PSMD9	7620
UBE2M	7477
PSMD2	7411
PSMA1	7329
PSMD1	7241
PSMB3	7171
PSMA7	7096
PSMC1	7021
PPP3CB	7005
TAB2	6964
PSMB6	6813
NFKBIA	6807
PSMF1	6659
CARD9	6648
UBB	6639
PSMC6	6635
PSMD12	6556
AHCYL1	6456
NFKB1	6277
PSMD11	6231
PPP3CA	6217
FBXW11	6196
PDPK1	6136
PSMA6	5970
PSMD7	5963
PSMD13	5948
BCL10	5849
ITPR2	5842
PSMD8	5757
TAB1	5681
UBE2V1	5637
CLEC7A	5608
IKBKG	5377
PSMA2	5339
PLCG2	5006
IL1B	4807
UBE2D2	4657
PSMD3	4618
UBC	4439
SEM1	4348
SKP1	4287
PSMB2	4084
RELB	3721
PSMD5	3426
PSMB1	3374
TAB3	3160
PSMD14	2611
PSMC2	2598
PSMB4	2523
MAP3K7	2395
PSMC3	1976
UBE2N	1936
PSMD10	1559
UBA52	1121
TRAF6	-229
PSMA4	-616
PSMC5	-863
NFKB2	-1165
RELA	-1803
CALM1	-2081
PSMB8	-3076
BTRC	-4924
PSMA3	-5285
IKBKB	-5386
PSMB10	-5735
PSMA5	-6053
PSME4	-6087
RPS27A	-6938
PSMA8	-7606
ITPR1	-7629
SRC	-8820
PSMC4	-9127
NFATC1	-9147
PSME1	-9991
ITPR3	-10308
PSME2	-10336
MALT1	-10920
PSMB9	-11324
CUL1	-11330
CASP8	-11336
MAP3K14	-11702
CARD11	-12160
NFATC3	-12177
NFATC2	-12294

---

DNA strand elongation

DNA strand elongation

	247
set	DNA strand elongation
setSize	32
pANOVA	3.21e-07
s.dist	-0.522
p.adjustANOVA	4.92e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MCM3	-12200
POLA1	-12150
MCM7	-12129
RPA1	-12004
RFC5	-11712
POLA2	-11575
LIG1	-11053
MCM8	-10944
RFC4	-10702
FEN1	-10593
GINS3	-10508
RFC3	-10489
POLD2	-10351
GINS4	-10236
PRIM1	-10191
MCM6	-9715
RPA3	-8911
MCM4	-8701
RFC1	-7437
MCM5	-7292

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MCM3	-12200
POLA1	-12150
MCM7	-12129
RPA1	-12004
RFC5	-11712
POLA2	-11575
LIG1	-11053
MCM8	-10944
RFC4	-10702
FEN1	-10593
GINS3	-10508
RFC3	-10489
POLD2	-10351
GINS4	-10236
PRIM1	-10191
MCM6	-9715
RPA3	-8911
MCM4	-8701
RFC1	-7437
MCM5	-7292
MCM2	-7223
RPA2	-6306
PCNA	-5969
PRIM2	-5575
GINS2	-4815
GINS1	-4401
DNA2	-2858
CDC45	-2659
POLD1	204
RFC2	4948
POLD4	6336
POLD3	8885

---

Signaling by BRAF and RAF fusions

Signaling by BRAF and RAF fusions

	1077
set	Signaling by BRAF and RAF fusions
setSize	57
pANOVA	3.3e-07
s.dist	0.391
p.adjustANOVA	4.99e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MAP2K1	9063
PAPSS1	9003
QKI	8996
AGTRAP	8956
MAPK3	8953
ITGA2B	8893
APBB1IP	8744
MARK3	8697
TLN1	8525
ARRB2	8490
AP3B1	8365
ITGB3	8291
FN1	8284
IQGAP1	8152
ATG7	8134
RAF1	7879
MAPK1	7493
BCL2L11	7384
VCL	7328
RAP1A	7305

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MAP2K1	9063
PAPSS1	9003
QKI	8996
AGTRAP	8956
MAPK3	8953
ITGA2B	8893
APBB1IP	8744
MARK3	8697
TLN1	8525
ARRB2	8490
AP3B1	8365
ITGB3	8291
FN1	8284
IQGAP1	8152
ATG7	8134
RAF1	7879
MAPK1	7493
BCL2L11	7384
VCL	7328
RAP1A	7305
KDM7A	6855
MAP2K2	6794
VWF	6641
YWHAB	6385
AGGF1	6191
NRAS	5363
FXR1	5308
CSK	5219
TRAK1	5022
FAM114A2	4963
KSR1	4167
LMNA	3887
SND1	3849
TRIM24	3806
KRAS	3702
KIAA1549	3618
RAP1B	3206
JAK2	2691
ARAF	2644
CLCN6	2232
ARRB1	1998
CAMK2G	1921
BRAF	1308
FAM131B	-734
CALM1	-2081
KSR2	-3361
HRAS	-3382
CNKSR2	-4781
AKAP9	-5020
CNKSR1	-7089
SRC	-8820
ZC3HAV1	-10064
MPRIP	-10959
TENT4A	-11168
PEBP1	-11270
CAMK2D	-11816
AGK	-12120

---

Intracellular signaling by second messengers

Intracellular signaling by second messengers

	574
set	Intracellular signaling by second messengers
setSize	273
pANOVA	3.32e-07
s.dist	0.179
p.adjustANOVA	4.99e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PPARG	9522
PRKACA	9429
LAMTOR1	9411
GRB2	9304
RCOR1	9073
AGO4	9070
PHC2	9043
PIK3CB	9038
VAPA	9033
PRKCD	9008
ADCY3	8984
KL	8963
MAPK3	8953
TGFA	8889
HGF	8863
MKRN1	8817
RAC1	8793
RRAGD	8753
RNF146	8696
FOXO3	8682

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PPARG	9522
PRKACA	9429
LAMTOR1	9411
GRB2	9304
RCOR1	9073
AGO4	9070
PHC2	9043
PIK3CB	9038
VAPA	9033
PRKCD	9008
ADCY3	8984
KL	8963
MAPK3	8953
TGFA	8889
HGF	8863
MKRN1	8817
RAC1	8793
RRAGD	8753
RNF146	8696
FOXO3	8682
SNAI1	8645
PRKAR1A	8607
IRS2	8569
LAMTOR5	8498
RHOG	8487
PSMB7	8485
PTEN	8460
PSMD4	8402
INSR	8282
PSME3	8251
PPP2CA	8234
EGF	8179
TRIM27	8142
MYD88	8136
CAMKK2	8125
PSMB5	8101
WWP2	8013
CHUK	7966
PRKAR1B	7918
VAV1	7896
AKT1S1	7865
PSMD6	7846
PIK3AP1	7811
GSK3A	7760
PPP2CB	7712
CASP9	7685
RHEB	7669
PSMD9	7620
LAMTOR3	7574
LAMTOR2	7567
MAPK1	7493
IER3	7463
PSMD2	7411
PSMA1	7329
PSMD1	7241
PSMB3	7171
IL1RAP	7150
PSMA7	7096
PSMC1	7021
BAD	6892
PSMB6	6813
PPP2R5B	6774
PRKAR2B	6741
PSMF1	6659
UBB	6639
PSMC6	6635
GSK3B	6634
PSMD12	6556
AHCYL1	6456
PIP5K1B	6450
FOXO4	6391
CSNK2A2	6388
USP7	6323
CAMKK1	6317
RRAGA	6244
PSMD11	6231
NEDD4	6201
CSNK2A1	6199
PRKAR2A	6166
PDPK1	6136
IRAK1	6131
HDAC7	6122
PIP5K1A	6110
GRK2	6068
PIK3CD	6046
AREG	5977
PSMA6	5970
PSMD7	5963
PSMD13	5948
PPP2R5A	5897
PDE1B	5874
PDGFRA	5858
ITPR2	5842
PSMD8	5757
MAF1	5723
GAB1	5679
AGO1	5654
HDAC2	5482
CBX8	5448
PSMA2	5339
PTPN11	5314
PDGFA	5293
ADCY4	5270
RAC2	5163
MAPKAP1	5057
HBEGF	5013
PIK3R2	5010
RRAGC	4954
HDAC5	4710
HDAC3	4673
PIK3CA	4629
PSMD3	4618
PPP2R1A	4589
CDKN1A	4511
LAMTOR4	4441
UBC	4439
SEM1	4348
MDM2	4312
PSMB2	4084
CBX6	4033
CSNK2B	3969
FGF2	3920
NRG1	3750
JUN	3722
STRN	3695
PHLPP1	3658
AKT1	3614
RNF2	3513
PSMD5	3426
PIP5K1C	3419
PSMB1	3374
IL1RL1	3175
EGR1	3124
GATAD2A	3075
AGO2	2995
SLC38A9	2807
EPGN	2662
PSMD14	2611
PSMC2	2598
PSMB4	2523
PPP2R5D	2421
CBX4	2222
ATF2	2085
PSMC3	1976
CAMK2G	1921
EREG	1888
IRS1	1741
MECOM	1687
PSMD10	1559
XIAP	1407
PRKCA	1132
UBA52	1121
REST	865
RPS6KB2	700
HDAC1	587
IL33	445
AKT2	433
MLST8	376
ATN1	234
ADCY9	123
CD86	-14
FRK	-24
TRAF6	-229
PPP2R1B	-241
ERBB3	-472
TNKS2	-499
MBD3	-528
PSMA4	-616
PPP2R5E	-680
NBEA	-703
RRAGB	-713
TSC2	-804
PSMC5	-863
AGO3	-1011
STUB1	-1032
CREB1	-1378
ADCY6	-1608
GATAD2B	-1759
RBBP4	-1870
NRG4	-1875
CALM1	-2081
PIP4K2A	-2365
SUZ12	-2409
ADCY2	-2896
MTA1	-3005
PSMB8	-3076
ADCY7	-3286
FGFR4	-3293
FRS2	-3433
CD19	-3843
RING1	-4063
FGF7	-4247
CHD4	-4515
TNRC6B	-4518
CBX2	-4617
PTENP1	-5280
PSMA3	-5285
FGFR1	-5352
TNRC6A	-5613
PSMB10	-5735
SCMH1	-5839
TRIB3	-5843
PSMA5	-6053
PSME4	-6087
SALL4	-6112
FOXO6	-6367
FGF23	-6622
USP13	-6737
NR4A1	-6756
CD80	-6841
KPNA2	-6910
RPS27A	-6938
MTA2	-7317
TRAT1	-7535
PSMA8	-7606
ITPR1	-7629
PIP4K2B	-7788
PRKCE	-8001
PHC3	-8152
CDKN1B	-8207
ADCY5	-8235
PHC1	-8402
PDGFB	-8577
FGF22	-8607
PML	-8693
TNKS	-8738
FGF9	-8761
SRC	-8820
ESR1	-9122
PSMC4	-9127
ESR2	-9250
EED	-9348
KDM1A	-9430
MTA3	-9433
ICOS	-9434
FOXO1	-9465
PIK3R1	-9505
RICTOR	-9670
CHD3	-9737
EZH2	-9741
MTOR	-9767
BMI1	-9829
CAMK4	-9956
PSME1	-9991
CD28	-10202
ITPR3	-10308
PSME2	-10336
MIR25	-10350
PRKX	-10428
RPTOR	-10464
OTUD3	-10763
TP53	-10893
KIT	-11004
THEM4	-11069
PLCG1	-11120
CNOT6L	-11248
PPP2R5C	-11265
PSMB9	-11324
PIP4K2C	-11371
PDGFRB	-11545
FYN	-11675
FGFR2	-11785
CAMK2D	-11816
TNRC6C	-11828
LCK	-11838
AKT3	-11849
PHLPP2	-11948
PRKACB	-11959
PRR5	-11985
MOV10	-11991
PIK3R3	-12015
RBBP7	-12155
ERBB2	-12320

---

Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

	1007
set	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
setSize	124
pANOVA	3.67e-07
s.dist	0.264
p.adjustANOVA	5.45e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ETFA	8658
NDUFB3	8430
SDHC	8390
NDUFB9	8237
NDUFAF1	8167
UQCRH	8073
ETFDH	8052
UQCRC1	7859
COX7A2L	7719
ETFB	7688
ATP5PD	7637
SDHB	7587
NDUFB1	7578
ATP5PB	7551
NDUFAF3	6981
SDHD	6963
UQCR11	6907
TIMMDC1	6822
ATP5F1C	6687
COX8A	6611

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ETFA	8658
NDUFB3	8430
SDHC	8390
NDUFB9	8237
NDUFAF1	8167
UQCRH	8073
ETFDH	8052
UQCRC1	7859
COX7A2L	7719
ETFB	7688
ATP5PD	7637
SDHB	7587
NDUFB1	7578
ATP5PB	7551
NDUFAF3	6981
SDHD	6963
UQCR11	6907
TIMMDC1	6822
ATP5F1C	6687
COX8A	6611
ATP5MF	6519
ATP5F1B	6497
NDUFA4	6459
ATP5F1A	6441
ATP5PF	6373
NDUFS1	6348
UQCRFS1	6325
COX5B	6207
NDUFS5	6178
COX5A	6168
ATP5F1E	6142
NDUFC2	6093
NDUFS2	6080
NDUFA6	6009
ATP5MC3	5906
UQCRC2	5852
NDUFB10	5812
NDUFAB1	5759
NDUFA1	5718
COX6B1	5667
NDUFA7	5623
ATP5MG	5512
NDUFC1	5343
NDUFV3	5214
COX6A1	5095
NDUFA2	4966
ECSIT	4918
NDUFA8	4804
ATP5PO	4794
NDUFB4	4553
COX7B	4465
TACO1	4406
UQCR10	4378
NDUFV2	4288
NDUFA13	4244
NDUFB6	4218
COX4I1	4191
NDUFS6	4155
COQ10B	3989
NDUFS4	3986
NDUFB5	3892
UQCRB	3834
SURF1	3532
CYC1	3047
ATP5F1D	2968
UQCRQ	2960
ATP5MC2	2956
NDUFAF7	2726
ATP5ME	2664
NDUFB7	2292
NDUFAF2	2133
NDUFS7	2118
NDUFA11	1458
NDUFB11	1172
NDUFB8	965
UCP2	913
NDUFS3	884
MT-ND4	840
COX6C	706
MT-CO1	684
COX7C	564
NDUFA3	503
MT-ND6	459
COX16	132
NDUFS8	81
MT-CO2	48
MT-CO3	40
ACAD9	-879
CYCS	-1334
COX14	-1496
NDUFA12	-1728
MT-ATP6	-2096
MT-ND5	-2166
MT-CYB	-2254
NDUFAF6	-2331
MT-ATP8	-3067
MT-ND1	-3616
MT-ND3	-3649
SCO2	-4351
SLC25A27	-4356
NDUFB2	-4446
SLC25A14	-4642
NDUFA5	-4723
COX20	-5018
SDHA	-5579
COX18	-6126
MT-ND2	-6560
COX19	-6882
NDUFA10	-6994
DMAC2L	-7274
ATP5MC1	-7616
TMEM126B	-8346
NDUFA9	-8864
NDUFAF5	-9499
SCO1	-9819
PM20D1	-9905
NDUFAF4	-10063
LRPPRC	-10081
UCP3	-10214
TRAP1	-10796
COQ10A	-11405
NDUFV1	-11466
COX11	-11539
NUBPL	-11628

---

C-type lectin receptors (CLRs)

C-type lectin receptors (CLRs)

	120
set	C-type lectin receptors (CLRs)
setSize	129
pANOVA	3.78e-07
s.dist	0.259
p.adjustANOVA	5.55e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PRKACA	9429
UBE2D1	9187
CLEC4D	9185
SYK	9076
PRKCD	9008
PYCARD	8638
CDC34	8611
PSMB7	8485
PSMD4	8402
CLEC4E	8324
CLEC4A	8260
PSME3	8251
PAK1	8230
PAK2	8185
PPP3R1	8175
FCER1G	8131
PSMB5	8101
CHUK	7966
RAF1	7879
PSMD6	7846

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PRKACA	9429
UBE2D1	9187
CLEC4D	9185
SYK	9076
PRKCD	9008
PYCARD	8638
CDC34	8611
PSMB7	8485
PSMD4	8402
CLEC4E	8324
CLEC4A	8260
PSME3	8251
PAK1	8230
PAK2	8185
PPP3R1	8175
FCER1G	8131
PSMB5	8101
CHUK	7966
RAF1	7879
PSMD6	7846
LYN	7809
ICAM3	7808
UBA3	7767
PSMD9	7620
UBE2M	7477
PSMD2	7411
PSMA1	7329
PSMD1	7241
PSMB3	7171
PSMA7	7096
PSMC1	7021
PPP3CB	7005
TAB2	6964
PSMB6	6813
NFKBIA	6807
CLEC6A	6730
PSMF1	6659
CARD9	6648
UBB	6639
PSMC6	6635
MUC1	6573
PSMD12	6556
AHCYL1	6456
NFKB1	6277
PSMD11	6231
PPP3CA	6217
FBXW11	6196
PDPK1	6136
EP300	6129
PSMA6	5970
PSMD7	5963
PSMD13	5948
BCL10	5849
ITPR2	5842
PSMD8	5757
TAB1	5681
UBE2V1	5637
CLEC7A	5608
IKBKG	5377
NRAS	5363
PSMA2	5339
PLCG2	5006
IL1B	4807
UBE2D2	4657
PSMD3	4618
UBC	4439
SEM1	4348
SKP1	4287
PSMB2	4084
RELB	3721
KRAS	3702
PSMD5	3426
CREBBP	3423
PSMB1	3374
TAB3	3160
PSMD14	2611
PSMC2	2598
PSMB4	2523
MAP3K7	2395
PSMC3	1976
UBE2N	1936
PSMD10	1559
UBA52	1121
TRAF6	-229
PSMA4	-616
PSMC5	-863
NFKB2	-1165
RELA	-1803
CALM1	-2081
MUCL1	-2211
MUC6	-2977
PSMB8	-3076
MUC4	-3191
HRAS	-3382
MUC16	-4104
PAK3	-4184
MUC5B	-4613
BTRC	-4924
PSMA3	-5285
CLEC10A	-5299
IKBKB	-5386
PSMB10	-5735
MUC20	-5962
PSMA5	-6053
PSME4	-6087
RPS27A	-6938
PSMA8	-7606
ITPR1	-7629
SRC	-8820
PSMC4	-9127
CD209	-9143
NFATC1	-9147
PSME1	-9991
ITPR3	-10308
PSME2	-10336
MUC12	-10704
MALT1	-10920
PSMB9	-11324
CUL1	-11330
CASP8	-11336
RPS6KA5	-11594
FYN	-11675
MAP3K14	-11702
CLEC4C	-11809
PRKACB	-11959
ICAM2	-12026
CARD11	-12160
NFATC3	-12177
NFATC2	-12294

---

RNA Polymerase II Transcription

RNA Polymerase II Transcription

	910
set	RNA Polymerase II Transcription
setSize	1204
pANOVA	4.09e-07
s.dist	-0.0867
p.adjustANOVA	5.95e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FASLG	-12371
TFDP2	-12364
RUNX3	-12352
ERBB2	-12320
NFATC2	-12294
ZNF599	-12232
PTPN4	-12220
RAD1	-12206
GATA3	-12191
ZNF287	-12168
ZNF3	-12165
RBBP7	-12155
YES1	-12142
PRKCQ	-12127
AUTS2	-12089
ZNF530	-12068
MDC1	-12059
WRN	-12047
TP53RK	-12040
ZNF74	-12012

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FASLG	-12371.0
TFDP2	-12364.0
RUNX3	-12352.0
ERBB2	-12320.0
NFATC2	-12294.0
ZNF599	-12232.0
PTPN4	-12220.0
RAD1	-12206.0
GATA3	-12191.0
ZNF287	-12168.0
ZNF3	-12165.0
RBBP7	-12155.0
YES1	-12142.0
PRKCQ	-12127.0
AUTS2	-12089.0
ZNF530	-12068.0
MDC1	-12059.0
WRN	-12047.0
TP53RK	-12040.0
ZNF74	-12012.0
RPA1	-12004.0
MOV10	-11991.0
PRR5	-11985.0
RORA	-11979.0
ANAPC1	-11962.0
ZNF461	-11956.0
FANCI	-11927.0
ZNF33B	-11911.0
ZNF549	-11908.0
ZNF250	-11889.0
DLL1	-11885.0
SMAD7	-11872.0
GLS	-11862.0
NUAK1	-11853.0
AKT3	-11849.0
ZNF70	-11832.0
TNRC6C	-11828.0
CAMK2D	-11816.0
ZNF43	-11813.0
ZNF682	-11811.0
ZNF500	-11806.0
DYRK2	-11799.0
DGCR8	-11798.0
ZNF286A	-11794.0
ZNF571	-11792.0
ZNF607	-11784.0
PARP1	-11764.0
SMAD3	-11745.0
CCND2	-11734.0
ZNF620	-11732.0
STAT1	-11727.0
RFC5	-11712.0
CCNE1	-11707.0
ZNF736	-11692.0
ZNF696	-11688.0
SMARCD1	-11679.0
ZNF568	-11661.0
ZNF554	-11652.0
PPP1R13B	-11636.0
BRIP1	-11605.0
ZNF337	-11599.0
NR2C2AP	-11589.0
ZNF724	-11586.0
ZNF517	-11582.0
ZNF570	-11569.0
FANCC	-11548.0
COX11	-11539.0
DDB2	-11530.0
ZNF569	-11521.0
ZNF235	-11519.0
ATRIP	-11486.0
MSH2	-11484.0
ZNF566	-11481.0
ZNF496	-11478.0
JMY	-11472.0
ZNF707	-11464.0
ZNF30	-11462.0
KRBOX4	-11452.0
ZNF419	-11446.0
ZNF740	-11444.0
RAD9A	-11435.0
ZNF136	-11433.0
RNPS1	-11427.0
FANCD2	-11424.0
RAD51D	-11415.0
CENPJ	-11406.0
ZNF773	-11396.0
PIP4K2C	-11371.0
ZNF138	-11364.0
SUPT16H	-11359.0
ZNF211	-11357.0
ZNF551	-11356.0
ZNF202	-11351.0
ZNF510	-11341.0
CUL1	-11330.0
PSMB9	-11324.0
ZNF600	-11320.0
CDC23	-11304.0
ZNF383	-11291.0
ZNF660	-11282.0
PPP2R5C	-11265.0
CDK4	-11256.0
CNOT6L	-11248.0
ZKSCAN8	-11246.0
ZNF528	-11244.0
ZNF248	-11241.0
ZNF649	-11216.0
ZNF354C	-11213.0
ZNF14	-11212.0
ZNF343	-11182.0
ZFP30	-11171.0
RUNX2	-11163.0
SSRP1	-11162.0
ATM	-11148.0
ZNF75D	-11137.0
ZNF550	-11136.0
ZNF584	-11134.0
ZNF133	-11128.0
SKI	-11113.0
ZNF519	-11101.0
ZNF540	-11097.0
RNMT	-11086.0
WWOX	-11085.0
ZNF77	-11084.0
PLXNA4	-11083.0
ZNF184	-11077.0
SRSF5	-11067.0
PCBP4	-11063.0
ZNF548	-11049.0
ITGA4	-11043.0
ZIK1	-11040.0
ZNF19	-11034.0
ZNF678	-11020.0
ZNF621	-11018.0
KIT	-11004.0
BRD1	-10991.0
PMAIP1	-10986.0
ZNF324B	-10972.0
ANAPC5	-10967.0
ZNF226	-10966.0
ZNF432	-10951.0
ZNF703	-10910.0
ZNF441	-10905.0
TP53	-10893.0
ZNF10	-10857.0
MECP2	-10855.0
ITGAL	-10847.0
TP63	-10842.0
ZNF302	-10830.0
KAT2A	-10771.0
L3MBTL2	-10770.0
KMT2A	-10725.0
ZNF257	-10712.0
RFC4	-10702.0
ZNF23	-10692.0
ZNF180	-10670.0
ATAD2	-10660.0
ZNF253	-10652.0
PRMT6	-10628.0
NR3C2	-10625.0
FBXO32	-10607.0
ZNF585B	-10598.0
ZNF266	-10587.0
DAXX	-10575.0
ZNF563	-10567.0
ZFP1	-10563.0
ZNF790	-10520.0
MAF	-10499.0
SIN3A	-10493.0
ZNF420	-10490.0
RFC3	-10489.0
ZNF675	-10478.0
ZNF529	-10469.0
RPTOR	-10464.0
ZNF544	-10460.0
ZNF749	-10456.0
ZNF473	-10444.0
SMYD2	-10431.0
LSM11	-10415.0
ZNF595	-10393.0
CTLA4	-10363.0
ATR	-10354.0
ZNF92	-10349.0
SMURF2	-10340.0
PSME2	-10336.0
ZNF112	-10327.0
NR1D2	-10325.0
RAD17	-10307.0
LDB1	-10303.0
ZNF778	-10297.0
ZNF680	-10286.0
AXIN1	-10285.0
IFNG	-10277.0
ZNF446	-10274.0
GPAM	-10241.0
THOC1	-10238.0
ZNF799	-10216.0
ZFPM1	-10195.0
TCF7	-10173.0
ZFP14	-10160.0
ZNF212	-10128.0
WWP1	-10106.0
TGIF2	-10105.0
ZNF737	-10092.0
ZC3H8	-10090.0
LRPPRC	-10081.0
ING5	-10037.0
MLLT3	-10022.0
ZNF626	-10014.0
SRSF11	-10002.0
PSME1	-9991.0
ZNF224	-9977.0
PERP	-9973.0
NFYB	-9964.0
RBL1	-9959.0
CAMK4	-9956.0
NOP2	-9952.0
MGA	-9948.0
ZNF436	-9945.0
EPC1	-9926.0
NR2C1	-9913.0
ZNF26	-9910.0
ZNF45	-9897.0
ZNF483	-9883.0
ZNF324	-9879.0
ZNF596	-9874.0
ZNF708	-9864.0
ZNF573	-9862.0
ZNF582	-9837.0
BMI1	-9829.0
ZNF664	-9828.0
SCO1	-9819.0
ZNF227	-9818.0
ZNF485	-9810.0
ZNF263	-9806.0
GATA2	-9800.0
MED15	-9778.0
MTOR	-9767.0
HEY2	-9752.0
EZH2	-9741.0
CHD3	-9737.0
ZNF157	-9718.0
ZNF583	-9711.0
ZNF311	-9705.0
BRD2	-9688.0
RICTOR	-9670.0
ZNF704	-9660.0
ZNF793	-9654.0
ZNF597	-9642.0
ZNF431	-9641.0
ZNF470	-9630.0
ZFP90	-9613.0
TXNIP	-9600.0
ZNF354B	-9598.0
ZNF684	-9580.0
ZNF614	-9572.0
ZNF689	-9559.0
NCBP2	-9558.0
NPM1	-9532.0
ZNF484	-9525.0
ZSCAN25	-9513.0
ZFP69	-9488.0
CCNT1	-9469.0
FOXO1	-9465.0
IGFBP3	-9455.0
ZNF506	-9443.0
CPSF4	-9416.0
ZNF41	-9405.0
ZNF17	-9349.0
EED	-9348.0
TRPC3	-9343.0
ZNF767P	-9339.0
ZNF625	-9336.0
MAGOHB	-9327.0
ZNF606	-9322.0
INTS4	-9307.0
CBX5	-9272.0
ESR2	-9250.0
PRMT1	-9229.0
MED27	-9191.0
TBP	-9167.0
ZNF141	-9154.0
ZNF677	-9144.0
PSMC4	-9127.0
ESR1	-9122.0
ZNF727	-9121.0
ZNF782	-9113.0
ZNF738	-9086.0
ZNF709	-9071.0
ZNF699	-9037.0
ZNF317	-9010.0
ZNF439	-9000.0
ZNF160	-8989.0
ZNF567	-8988.0
NR1D1	-8980.0
SESN1	-8962.0
ICE2	-8945.0
RPAP2	-8928.0
ZNF721	-8922.0
RPA3	-8911.0
ZNF416	-8903.0
ZNF681	-8899.0
SRSF7	-8892.0
SMARCC1	-8880.0
SIRT3	-8857.0
PRDM1	-8856.0
ZNF792	-8839.0
TRIM33	-8823.0
SRC	-8820.0
ZNF433	-8780.0
ZNF79	-8769.0
ZNF140	-8760.0
ZNF619	-8735.0
ZNF440	-8730.0
AIFM2	-8727.0
ZNF717	-8709.0
ZNF331	-8698.0
PML	-8693.0
EHMT1	-8692.0
MNAT1	-8687.0
TGIF1	-8682.0
ZNF274	-8667.0
NR2C2	-8630.0
MED10	-8579.0
RORC	-8573.0
E2F5	-8568.0
EHMT2	-8558.0
MEN1	-8538.0
ZFP37	-8513.0
FOXP3	-8503.0
ZNF234	-8487.0
ZNF300	-8481.0
TAF1	-8476.0
ZNF559	-8467.0
L3MBTL1	-8461.0
PHC1	-8402.0
CDK13	-8392.0
ICE1	-8382.0
MAPKAPK5	-8364.0
SNAPC3	-8359.0
SMAD4	-8351.0
HDAC6	-8337.0
UPF3B	-8288.0
SKP2	-8279.0
HES1	-8266.0
CDKN1B	-8207.0
PRKAB2	-8172.0
PHC3	-8152.0
ZKSCAN3	-8126.0
MEAF6	-8105.0
LEF1	-8076.0
TAF4B	-8069.0
ZNF720	-8041.0
ZNF665	-7990.0
ZNF175	-7950.0
THOC3	-7934.0
FIP1L1	-7928.0
MRE11	-7923.0
GLI3	-7910.0
INTS7	-7902.0
ZNF726	-7889.0
ZNF641	-7885.0
ZNF688	-7872.0
BBC3	-7864.0
CDC7	-7855.0
ZNF135	-7853.0
ZNF521	-7834.0
ZNF12	-7825.0
RGCC	-7821.0
ZNF585A	-7814.0
ZNF671	-7797.0
PIP4K2B	-7788.0
ERCC3	-7783.0
ZNF75A	-7752.0
RBL2	-7743.0
ZNF382	-7731.0
TNFRSF18	-7726.0
WDR33	-7715.0
GLS2	-7702.0
ZNF702P	-7701.0
ZNF771	-7686.0
ZNF2	-7673.0
ZNF320	-7647.0
ZNF273	-7623.0
PSMA8	-7606.0
ZNF577	-7605.0
ZNF418	-7559.0
ZNF791	-7534.0
RBM14	-7497.0
ACTL6A	-7468.0
ZNF264	-7412.0
ANAPC2	-7407.0
RBM8A	-7393.0
MED24	-7387.0
YAF2	-7378.0
RAD50	-7373.0
TAF6	-7352.0
YWHAQ	-7340.0
MTA2	-7317.0
ZNF711	-7253.0
ZNF195	-7249.0
NABP2	-7240.0
BRPF1	-7218.0
TCF3	-7215.0
IL2RA	-7161.0
GAMT	-7054.0
ZNF785	-7032.0
ZNF777	-6997.0
CCND1	-6970.0
RPS27A	-6938.0
ZNF764	-6912.0
ZNF786	-6907.0
ZNF223	-6903.0
ZNF425	-6900.0
ZNF268	-6887.0
COX19	-6882.0
MLH1	-6872.0
ZFP28	-6824.0
MED23	-6787.0
NR4A1	-6756.0
SUPT5H	-6716.0
PIDD1	-6647.0
ANAPC4	-6644.0
ZNF33A	-6630.0
ZNF691	-6627.0
BRPF3	-6615.0
ZKSCAN7	-6609.0
FBXW7	-6600.0
GAD2	-6585.0
ZNF415	-6564.0
H2BU1	-6555.0
DDX39A	-6544.0
INTS9	-6543.0
CDK6	-6465.0
ZNF480	-6459.0
TAF15	-6454.0
CSTF2	-6444.0
RHNO1	-6437.0
SUPT6H	-6407.0
SRSF2	-6396.0
PPARD	-6394.0
THRA	-6387.0
ZNF616	-6382.0
TJP1	-6374.0
FOXO6	-6367.0
ZNF208	-6363.0
RPA2	-6306.0
NELFCD	-6277.0
TFAP2E	-6266.0
AGRP	-6243.0
ZNF169	-6234.0
ZNF442	-6204.0
TCF7L2	-6185.0
ZNF610	-6184.0
CSTF2T	-6171.0
RNF34	-6150.0
WWTR1	-6131.0
SYMPK	-6129.0
COX18	-6126.0
CSTF1	-6113.0
KRBA1	-6098.0
PSME4	-6087.0
KMT2E	-6073.0
CDC16	-6071.0
PSMA5	-6053.0
ZNF706	-6049.0
ZNF493	-6035.0
ZNF557	-5971.0
PCNA	-5969.0
ZNF662	-5963.0
ZNF154	-5946.0
TAF2	-5945.0
ZNF543	-5942.0
NCBP1	-5853.0
ZNF398	-5842.0
SCMH1	-5839.0
NOC2L	-5831.0
ZNF761	-5813.0
FYTTD1	-5794.0
E2F7	-5780.0
SETD1A	-5744.0
PSMB10	-5735.0
ZNF713	-5668.0
ZNF514	-5664.0
ZNF718	-5657.0
ZNF101	-5614.0
TNRC6A	-5613.0
MAMLD1	-5584.0
ZNF658	-5581.0
ZNF34	-5577.0
ZFP69B	-5558.0
ZNF71	-5533.0
ZNF589	-5519.0
PMS2	-5514.0
ARID1B	-5504.0
TNKS1BP1	-5490.0
MED30	-5484.0
ZNF25	-5459.0
ZNF417	-5416.0
SRSF6	-5402.0
BLK	-5388.0
ZNF99	-5349.0
ZNF615	-5323.0
ZNF547	-5291.0
PSMA3	-5285.0
PHAX	-5261.0
SRRT	-5248.0
RABGGTB	-5240.0
ZNF285	-5239.0
CDKN2A	-5236.0
ZNF37A	-5230.0
NOTCH4	-5229.0
CCNT2	-5205.0
BTG1	-5201.0
ANAPC7	-5181.0
ZKSCAN4	-5161.0
RARG	-5153.0
ZNF443	-5146.0
RBBP8	-5105.0
NR4A3	-5082.0
TRIM28	-5056.0
SRRM1	-5050.0
PPARGC1B	-5047.0
COX20	-5018.0
ZNF155	-5014.0
CDK2	-5006.0
ANAPC10	-5000.0
E2F6	-4979.0
SOCS4	-4974.0
ZNF124	-4952.0
ZNF430	-4837.0
ZNF546	-4802.0
TP73	-4754.0
ZNF692	-4722.0
ZNF700	-4710.0
BLM	-4690.0
ZNF611	-4678.0
ZNF492	-4623.0
DHX38	-4620.0
CBX2	-4617.0
ZNF564	-4519.0
TNRC6B	-4518.0
CHD4	-4515.0
TAF5	-4514.0
RPRD2	-4513.0
ZNF460	-4477.0
NR1I2	-4435.0
ZNF197	-4430.0
ZNF426	-4382.0
SCO2	-4351.0
CHEK2	-4350.0
SMARCE1	-4315.0
U2AF1L4	-4295.0
ZNF561	-4292.0
CNOT1	-4265.0
DDX39B	-4243.0
SIN3B	-4205.0
SIRT1	-4197.0
SMARCC2	-4137.0
PCGF2	-4135.0
RING1	-4063.0
RMI2	-4050.0
ZNF486	-4043.0
MED1	-4036.0
POLR2D	-4024.0
ARID2	-3932.0
ZNF233	-3931.0
CDK9	-3927.0
YEATS4	-3919.0
NELFA	-3886.0
CNOT7	-3880.0
SMARCB1	-3869.0
PRELID3A	-3832.0
CPSF1	-3813.0
SNAPC5	-3794.0
TEAD2	-3774.0
ZNF334	-3744.0
ZSCAN32	-3733.0
ZNF215	-3708.0
NUDT21	-3702.0
PAX5	-3638.0
NR1H3	-3597.0
ZNF676	-3587.0
ZNF701	-3558.0
SESN3	-3546.0
GPX2	-3533.0
ZNF350	-3507.0
ZNF655	-3460.0
ZNF556	-3455.0
TOPBP1	-3450.0
CASP10	-3446.0
BARD1	-3419.0
BCL2L14	-3367.0
PCGF5	-3312.0
ZNF714	-3298.0
ZNF624	-3294.0
RXRB	-3276.0
UXT	-3252.0
PIN1	-3188.0
ZFP2	-3134.0
ZNF221	-3101.0
POLR2A	-3092.0
PSMB8	-3076.0
ZNF670	-3075.0
CTSV	-3036.0
PCF11	-3032.0
POLR2H	-2942.0
TAF11	-2938.0
GTF2H4	-2916.0
GTF2H1	-2913.0
DNA2	-2858.0
CASP6	-2831.0
HIVEP3	-2798.0
RAD51	-2767.0
PLK2	-2748.0
ZNF555	-2741.0
SMARCA2	-2737.0
CNOT10	-2718.0
TTC5	-2650.0
ZNF490	-2630.0
ABCA6	-2612.0
TAF9B	-2599.0
SMURF1	-2591.0
ZNF605	-2576.0
ZNF18	-2548.0
POLR2B	-2523.0
ZNF772	-2509.0
CHEK1	-2481.0
CASP2	-2471.0
RABGGTA	-2462.0
KAT2B	-2414.0
SUZ12	-2409.0
SNRPB	-2400.0
DDIT4	-2395.0
SNRPF	-2377.0
PIP4K2A	-2365.0
H19	-2361.0
ZNF860	-2350.0
OCLN	-2327.0
SRSF3	-2292.0
GTF2H3	-2235.0
FZR1	-2233.0
ZC3H11A	-2210.0
ZNF839	-2202.0
ANAPC16	-2123.0
TSC1	-2118.0
CNOT2	-2090.0
CALM1	-2081.0
CDK8	-1971.0
INTS2	-1936.0
PHF20	-1921.0
KCTD1	-1890.0
RBBP4	-1870.0
HSPD1	-1860.0
TAF3	-1850.0
RELA	-1803.0
POLR2K	-1783.0
GATAD2B	-1759.0
NR2F1	-1717.0
ZNF468	-1709.0
TAF4	-1698.0
RNU1-1	-1690.5
RFFL	-1683.0
ZNF669	-1660.0
ZNF28	-1618.0
NR4A2	-1601.0
EXO1	-1586.0
COX14	-1496.0
BGLAP	-1473.0
CHTOP	-1387.0
CREB1	-1378.0
CDK12	-1356.0
ZNF750	-1354.0
CYCS	-1334.0
CNOT4	-1286.0
SETD9	-1240.0
TCF12	-1233.0
MDM4	-1230.0
H2AZ2	-1209.0
CDK5R1	-1089.0
STUB1	-1032.0
ZNF627	-1022.0
AGO3	-1011.0
INTS5	-1001.0
ZNF562	-962.0
TCEA1	-943.0
ZNF565	-941.0
GPS2	-889.0
PSMC5	-863.0
MED6	-842.0
SNAPC4	-815.0
TSC2	-804.0
UBE2I	-764.0
SKIL	-725.0
MOBP	-714.0
RRAGB	-713.0
PCGF6	-689.0
ZNF558	-678.0
CDC27	-651.0
PSMA4	-616.0
NPPA	-584.0
MAML2	-582.0
MBD3	-528.0
PABPN1	-526.0
ZNF716	-489.0
MEF2C	-293.0
PPP2R1B	-241.0
MED14	-203.0
RRM2	-183.0
ZNF587	-164.0
ZNF200	-154.0
HUS1	-145.0
ZNF222	-84.0
ZNF347	-31.0
BRD7	-10.0
LEO1	39.0
MT-CO3	40.0
MT-CO2	48.0
KMT2C	63.0
WDR61	77.0
COX16	132.0
WDR5	155.0
KLF4	157.0
INTS12	172.0
APOE	218.0
MED7	224.0
ABL1	226.0
TCF7L1	275.0
ZNF100	276.0
TRIAP1	281.0
MYB	302.0
CSTF3	309.0
ZNF776	367.0
NELFB	374.0
MLST8	376.0
CSF1R	394.0
POLR2I	396.0
PPP1R13L	399.0
AKT2	433.0
PLAGL1	446.0
CCNB1	467.0
NR3C1	511.0
YY1	537.0
SNAPC1	549.0
COX7C	564.0
CCNA1	585.0
HDAC1	587.0
ELL3	621.0
SNRPE	628.0
CLDN5	650.0
MT-CO1	684.0
BANP	687.0
COX6C	706.0
SETD1B	736.0
INTS1	766.0
CCNH	774.0
KAT6A	794.0
PPARA	813.0
AURKB	846.0
THOC2	911.0
RBBP5	1037.0
ZNF429	1053.0
MAGOH	1054.0
UBA52	1121.0
RPRD1B	1159.0
KMT2B	1179.0
GCK	1193.0
TAF9	1250.0
U2AF1	1287.0
PRKAB1	1302.0
KAT5	1314.0
ITCH	1318.0
ZNF394	1319.0
PRKAA1	1322.0
ZKSCAN5	1336.0
HDAC9	1359.0
AFF4	1369.0
THRB	1429.0
MED31	1462.0
POU2F1	1537.0
CDK1	1540.0
TPX2	1551.0
PSMD10	1559.0
ATXN3	1601.0
SFN	1615.0
POLR2C	1616.0
ELF1	1630.0
SNRPG	1646.0
SNRPD3	1675.0
CCNA2	1685.0
KCTD15	1758.0
TNFRSF10A	1815.0
PVALB	1839.0
NR1I3	1855.0
CCNC	1877.0
CAMK2G	1921.0
ZNF658B	1948.0
ZNF613	1957.0
CAV1	1969.0
PSMC3	1976.0
PRKAG2	2015.0
MED12	2034.0
CBFB	2078.0
ATF2	2085.0
CNOT11	2102.0
TAF7	2139.0
OPRM1	2161.0
ZKSCAN1	2166.0
CBX4	2222.0
NBN	2267.0
CHM	2273.0
HDAC10	2280.0
GTF2E1	2287.0
STK11	2289.0
MYC	2304.0
SARNP	2436.0
SRSF1	2514.0
PSMB4	2523.0
MED13	2533.0
PSMC2	2598.0
MYBL2	2601.0
ELF2	2606.0
PSMD14	2611.0
DEK	2676.0
GTF2A1	2713.0
SLU7	2727.0
NRBP1	2786.0
SLC38A9	2807.0
POMC	2855.0
E2F8	2856.0
ZNF471	2869.0
CCNK	2877.0
ZNF586	2878.0
SUPT4H1	2890.0
CDC26	2923.0
ZNF770	2964.0
GTF2H2	2984.0
AGO2	2995.0
VENTX	3057.0
GATAD2A	3075.0
HDAC8	3079.0
MED17	3084.0
RNGTT	3088.0
RAD9B	3090.0
BTG2	3111.0
KMT2D	3203.0
HTT	3209.0
MED4	3215.0
THOC6	3225.0
SESN2	3311.0
AURKA	3330.0
ZNF445	3333.0
CTR9	3344.0
PSMB1	3374.0
CPSF7	3391.0
CREBBP	3423.0
PSMD5	3426.0
PRDX2	3428.0
PAF1	3478.0
ZNF189	3487.0
NFYA	3506.0
POLR2G	3508.0
RNF2	3513.0
GTF2B	3515.0
RTF1	3526.0
ZNF205	3530.0
SURF1	3532.0
ERCC2	3547.0
SSU72	3574.0
PRMT5	3600.0
AKT1	3614.0
TAF8	3620.0
U2AF2	3663.0
KRAS	3702.0
FAS	3712.0
JUN	3722.0
ZNF668	3725.0
BIRC5	3738.0
ZNF667	3739.0
DPY30	3757.0
SRSF4	3814.0
MAPK11	3826.0
TMEM219	3845.0
NELFE	3860.0
GTF2H5	3874.0
ZNF354A	3889.0
RBX1	3934.0
ZNF747	3949.0
CSNK2B	3969.0
PPARGC1A	3988.0
ZNF333	4007.0
CBX6	4033.0
PSMB2	4084.0
COX4I1	4191.0
CASP1	4224.0
CTSL	4231.0
MAX	4243.0
POU2F2	4251.0
SKP1	4287.0
INTS10	4291.0
MDM2	4312.0
SEM1	4348.0
KCTD6	4371.0
SOD2	4390.0
MED26	4395.0
TACO1	4406.0
ING2	4415.0
UBC	4439.0
LAMTOR4	4441.0
COX7B	4465.0
CDKN1A	4511.0
TBL1XR1	4556.0
RPRD1A	4573.0
PPP2R1A	4589.0
SGK1	4595.0
POLR2F	4604.0
PSMD3	4618.0
NDRG1	4647.0
HDAC3	4673.0
ZNF552	4685.0
ZNF20	4697.0
NOTCH1	4704.0
HDAC5	4710.0
SMARCA4	4733.0
UBE2S	4746.0
ZNF774	4747.0
HDAC11	4756.0
CNOT6	4799.0
DLX6	4817.0
CBX3	4825.0
ARID1A	4830.0
AR	4840.0
CCNG1	4881.0
ZNF282	4892.0
SMAD2	4905.0
DDIT3	4906.0
RFC2	4948.0
GTF2F1	4951.0
RRAGC	4954.0
CDC25C	4969.0
H2AC20	4972.0
NR2F6	4984.0
ELL	5009.0
CDC73	5020.0
SNAPC2	5038.0
ZNF775	5041.0
MAPKAP1	5057.0
CTSK	5059.0
COX6A1	5095.0
UBE2C	5101.0
GPRIN1	5131.0
CCNE2	5143.0
TGFB1	5153.0
SNW1	5201.0
CDK7	5211.0
CRADD	5216.0
CASC3	5242.0
NOTCH2	5272.0
MED16	5278.0
POLR2L	5305.0
H2BC15	5312.0
PTPN11	5314.0
CNOT3	5320.0
SLBP	5337.0
PSMA2	5339.0
H2BC9	5394.0
MAML1	5404.0
ALYREF	5432.0
GTF2F2	5434.0
CBX8	5448.0
FOS	5460.0
USP9X	5464.0
PRKAG1	5476.0
HDAC2	5482.0
TP53BP2	5532.0
EAF1	5533.0
RYBP	5535.0
PBRM1	5566.0
G6PC	5568.0
YWHAZ	5624.0
AGO1	5654.0
COX6B1	5667.0
INTS6	5673.0
PF4	5707.0
PTPN1	5722.0
KDM5B	5736.0
RNF111	5749.0
PSMD8	5757.0
GTF2E2	5767.0
PRELID1	5790.0
HIPK1	5855.0
NCOR1	5887.0
IWS1	5894.0
BAX	5916.0
ESRRA	5943.0
PSMD13	5948.0
ZNF213	5950.0
THBS1	5951.0
PSMD7	5963.0
PSMA6	5970.0
STEAP3	5996.0
ASH2L	6001.0
ZNF385A	6014.0
BID	6020.0
H2AZ1	6036.0
HIPK2	6078.0
HDAC7	6122.0
EP300	6129.0
IRAK1	6131.0
PDPK1	6136.0
ANAPC11	6161.0
COX5A	6168.0
CTDP1	6180.0
CSNK2A1	6199.0
TIGAR	6204.0
COX5B	6207.0
MED25	6209.0
PSMD11	6231.0
INTS3	6232.0
RRAGA	6244.0
BRCA1	6248.0
NFKB1	6277.0
GP1BA	6279.0
GPI	6284.0
THOC7	6293.0
E2F4	6300.0
USP7	6323.0
LSM10	6338.0
E2F1	6343.0
YWHAB	6385.0
CSNK2A2	6388.0
FOXO4	6391.0
CTNNB1	6408.0
RARA	6429.0
CITED2	6457.0
TP53INP1	6458.0
NDUFA4	6459.0
TAL1	6518.0
SREBF1	6539.0
PSMD12	6556.0
CLP1	6589.0
CPSF3	6602.0
EAF2	6605.0
COX8A	6611.0
CCNG2	6629.0
GSK3B	6634.0
PSMC6	6635.0
UBB	6639.0
PSMF1	6659.0
POLR2J	6671.0
PLK3	6680.0
ZNF230	6689.0
H3C15	6699.5
TWIST2	6721.0
MED20	6743.0
UBE2E1	6759.0
SATB2	6781.0
RRM2B	6798.0
CDC40	6801.0
JUNB	6806.0
PSMB6	6813.0
SUMO1	6889.0
ZNF710	6900.0
SMARCD2	6914.0
RMI1	6947.0
PSMC1	7021.0
PRDX1	7030.0
GTF2A2	7066.0
PSMA7	7096.0
PRKCB	7097.0
TAF10	7110.0
PAPOLA	7153.0
PSMB3	7171.0
ZNF267	7203.0
TAF13	7217.0
THOC5	7235.0
PSMD1	7241.0
ZNF143	7265.0
POLDIP3	7269.0
EIF4A3	7273.0
H2BC17	7285.0
ELOA	7312.0
PSMA1	7329.0
BCL2L11	7384.0
H2BC4	7389.0
PSMD2	7411.0
NR1H2	7415.0
SRSF9	7422.0
ZFHX3	7425.0
VEGFA	7467.0
ELOB	7482.0
SERPINE1	7483.0
CCND3	7487.0
MAPK1	7493.0
RXRA	7495.0
ELOC	7519.0
RUNX1	7529.0
MED8	7535.0
POLR2E	7563.0
LAMTOR2	7567.0
ZNF746	7573.0
LAMTOR3	7574.0
PSMD9	7620.0
NFYC	7653.0
ITGA5	7659.0
RHEB	7669.0
MYL9	7703.0
PPP2CB	7712.0
COX7A2L	7719.0
PPM1D	7810.0
MLLT1	7825.0
ELL2	7828.0
SMAD6	7835.0
CPSF2	7838.0
CITED4	7844.0
PSMD6	7846.0
NEDD4L	7875.0
TBL1X	7887.0
NOTCH3	7899.0
H2BC11	7912.0
H2AC6	7934.0
TNFRSF10C	7960.0
TOP3A	7973.0
TAF12	7977.0
NCOR2	7985.0
CEBPB	7997.0
NABP1	8001.0
H2BC5	8003.0
KMT5A	8005.0
NRBF2	8076.0
INTS8	8079.0
PSMB5	8101.0
LBR	8102.0
TXNRD1	8192.0
SP1	8193.0
PPM1A	8200.0
CNOT8	8227.0
PPP2CA	8234.0
PSME3	8251.0
TXN	8285.0
LMO2	8307.0
TNFRSF10B	8321.0
VDR	8348.0
PSMD4	8402.0
GATA1	8410.0
PTEN	8460.0
TFDP1	8470.0
PSMB7	8485.0
LAMTOR5	8498.0
SMAD1	8511.0
PRDX5	8531.0
NR6A1	8553.0
ARID3A	8584.0
CDK5	8616.0
UBE2D3	8640.0
YWHAH	8649.0
H3-3A	8661.0
SMARCD3	8668.0
FOXO3	8682.0
RB1	8707.0
JAG1	8743.0
LGALS3	8752.0
RRAGD	8753.0
RBPJ	8770.0
CDKN2B	8836.0
MAP2K6	8887.0
TGFA	8889.0
SPI1	8891.0
ITGA2B	8893.0
PINK1	8941.0
MAPK3	8953.0
MAML3	8957.0
HDAC4	8960.0
ANAPC15	8968.0
TP53I3	8979.0
RETN	8998.0
ZNF697	9002.0
G6PD	9004.0
APAF1	9015.0
CARM1	9020.0
SLC2A3	9021.0
PHC2	9043.0
YWHAE	9045.0
H2BC12	9051.0
AGO4	9070.0
TNFRSF10D	9072.0
GADD45A	9083.0
FKBP5	9091.0
MAPK14	9104.0
CAT	9123.0
BCL6	9175.0
UBE2D1	9187.0
GSR	9235.0
YWHAG	9264.0
H2BC21	9283.0
BNIP3L	9329.0
H2AJ	9374.0
NLRC4	9406.0
LAMTOR1	9411.0
PRKACA	9429.0
NFE2	9431.0
SOCS3	9476.0
CR1	9486.0
PPARG	9522.0

---

VEGFA-VEGFR2 Pathway

VEGFA-VEGFR2 Pathway

	1309
set	VEGFA-VEGFR2 Pathway
setSize	92
pANOVA	4.27e-07
s.dist	0.305
p.adjustANOVA	6.14e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
WASF1	9520
PRKACA	9429
CTNNA1	9341
NCF4	9268
CYFIP1	9265
NCF2	9190
MAPK14	9104
PIK3CB	9038
CYBB	9031
PRKCD	9008
CRK	8906
RAC1	8793
CDH5	8613
MAPKAPK3	8382
WASF2	8369
RHOA	8319
ITGB3	8291
PAK1	8230
PAK2	8185
PTK2B	7935

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
WASF1	9520
PRKACA	9429
CTNNA1	9341
NCF4	9268
CYFIP1	9265
NCF2	9190
MAPK14	9104
PIK3CB	9038
CYBB	9031
PRKCD	9008
CRK	8906
RAC1	8793
CDH5	8613
MAPKAPK3	8382
WASF2	8369
RHOA	8319
ITGB3	8291
PAK1	8230
PAK2	8185
PTK2B	7935
VAV1	7896
NCKAP1L	7673
SPHK1	7657
CDC42	7537
ROCK1	7489
VEGFA	7467
NCKAP1	7462
NCF1	7334
DOCK1	7314
PRKCB	7097
ABI1	7082
BRK1	7032
CYBA	6922
WASF3	6808
AHCYL1	6456
CTNNB1	6408
ELMO1	6258
PXN	6230
ROCK2	6138
PDPK1	6136
ITGAV	6106
SHB	6026
ITPR2	5842
NRAS	5363
MAPKAP1	5057
PIK3R2	5010
NCK2	4934
VAV3	4894
PIK3CA	4629
PTK2	4462
ELMO2	4397
SHC2	4183
MAPKAPK2	4054
MAPK13	3865
MAPK11	3826
KRAS	3702
AKT1	3614
RASA1	2106
CAV1	1969
HSPB1	1863
HSP90AA1	1326
PRKCA	1132
AKT2	433
MLST8	376
BAIAP2	-215
MAPK12	-1074
NOS3	-2059
CALM1	-2081
HRAS	-3382
VAV2	-4055
PAK3	-4184
JUP	-5353
TRIB3	-5843
ITPR1	-7629
CTNND1	-8403
SRC	-8820
PIK3R1	-9505
RICTOR	-9670
MTOR	-9767
ITPR3	-10308
CYFIP2	-10367
ABI2	-10915
THEM4	-11069
PLCG1	-11120
NCK1	-11454
PRKCZ	-11629
FYN	-11675
AKT3	-11849
PRKACB	-11959
PRR5	-11985
AXL	-12331
SH2D2A	-12359

---

MAP kinase activation

MAP kinase activation

	611
set	MAP kinase activation
setSize	63
pANOVA	4.52e-07
s.dist	0.367
p.adjustANOVA	6.44e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
DUSP3	9280
MAPK14	9104
MAP2K1	9063
MAPK3	8953
MAP2K6	8887
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PPP2CA	8234
MEF2A	8009
CHUK	7966
PPP2CB	7712
RPS6KA1	7695
MAPK1	7493
TAB2	6964
MAP2K4	6866
UBB	6639
NFKB1	6277
FBXW11	6196
MAP3K8	6160

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
DUSP3	9280
MAPK14	9104
MAP2K1	9063
MAPK3	8953
MAP2K6	8887
MAP2K3	8748
NOD2	8442
MAPKAPK3	8382
PPP2CA	8234
MEF2A	8009
CHUK	7966
PPP2CB	7712
RPS6KA1	7695
MAPK1	7493
TAB2	6964
MAP2K4	6866
UBB	6639
NFKB1	6277
FBXW11	6196
MAP3K8	6160
IRAK1	6131
ATF1	5706
TAB1	5681
UBE2V1	5637
TNIP2	5552
FOS	5460
IKBKG	5377
PPP2R1A	4589
UBC	4439
DUSP6	4357
MAPK10	4325
SKP1	4287
MAPKAPK2	4054
MAPK11	3826
JUN	3722
TAB3	3160
RPS6KA2	3087
RPS6KA3	2973
PPP2R5D	2421
MAP3K7	2395
ATF2	2085
UBE2N	1936
MAP2K7	1654
VRK3	1281
UBA52	1121
ELK1	1040
RIPK2	1025
TRAF6	-229
PPP2R1B	-241
MEF2C	-293
MAPK7	-1337
CREB1	-1378
DUSP7	-3211
BTRC	-4924
IKBKB	-5386
DUSP4	-6287
RPS27A	-6938
MAPK9	-7068
MAPK8	-9428
IRAK2	-9548
CUL1	-11330
RPS6KA5	-11594
NOD1	-12263

---

PIP3 activates AKT signaling

PIP3 activates AKT signaling

	792
set	PIP3 activates AKT signaling
setSize	241
pANOVA	6.02e-07
s.dist	0.187
p.adjustANOVA	8.47e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PPARG	9522
LAMTOR1	9411
GRB2	9304
RCOR1	9073
AGO4	9070
PHC2	9043
PIK3CB	9038
VAPA	9033
KL	8963
MAPK3	8953
TGFA	8889
HGF	8863
MKRN1	8817
RAC1	8793
RRAGD	8753
RNF146	8696
FOXO3	8682
SNAI1	8645
IRS2	8569
LAMTOR5	8498

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PPARG	9522
LAMTOR1	9411
GRB2	9304
RCOR1	9073
AGO4	9070
PHC2	9043
PIK3CB	9038
VAPA	9033
KL	8963
MAPK3	8953
TGFA	8889
HGF	8863
MKRN1	8817
RAC1	8793
RRAGD	8753
RNF146	8696
FOXO3	8682
SNAI1	8645
IRS2	8569
LAMTOR5	8498
RHOG	8487
PSMB7	8485
PTEN	8460
PSMD4	8402
INSR	8282
PSME3	8251
PPP2CA	8234
EGF	8179
TRIM27	8142
MYD88	8136
PSMB5	8101
WWP2	8013
CHUK	7966
VAV1	7896
AKT1S1	7865
PSMD6	7846
PIK3AP1	7811
GSK3A	7760
PPP2CB	7712
CASP9	7685
RHEB	7669
PSMD9	7620
LAMTOR3	7574
LAMTOR2	7567
MAPK1	7493
IER3	7463
PSMD2	7411
PSMA1	7329
PSMD1	7241
PSMB3	7171
IL1RAP	7150
PSMA7	7096
PSMC1	7021
BAD	6892
PSMB6	6813
PPP2R5B	6774
PSMF1	6659
UBB	6639
PSMC6	6635
GSK3B	6634
PSMD12	6556
PIP5K1B	6450
FOXO4	6391
CSNK2A2	6388
USP7	6323
RRAGA	6244
PSMD11	6231
NEDD4	6201
CSNK2A1	6199
PDPK1	6136
IRAK1	6131
HDAC7	6122
PIP5K1A	6110
PIK3CD	6046
AREG	5977
PSMA6	5970
PSMD7	5963
PSMD13	5948
PPP2R5A	5897
PDGFRA	5858
PSMD8	5757
MAF1	5723
GAB1	5679
AGO1	5654
HDAC2	5482
CBX8	5448
PSMA2	5339
PTPN11	5314
PDGFA	5293
RAC2	5163
MAPKAP1	5057
HBEGF	5013
PIK3R2	5010
RRAGC	4954
HDAC5	4710
HDAC3	4673
PIK3CA	4629
PSMD3	4618
PPP2R1A	4589
CDKN1A	4511
LAMTOR4	4441
UBC	4439
SEM1	4348
MDM2	4312
PSMB2	4084
CBX6	4033
CSNK2B	3969
FGF2	3920
NRG1	3750
JUN	3722
STRN	3695
PHLPP1	3658
AKT1	3614
RNF2	3513
PSMD5	3426
PIP5K1C	3419
PSMB1	3374
IL1RL1	3175
EGR1	3124
GATAD2A	3075
AGO2	2995
SLC38A9	2807
EPGN	2662
PSMD14	2611
PSMC2	2598
PSMB4	2523
PPP2R5D	2421
CBX4	2222
ATF2	2085
PSMC3	1976
EREG	1888
IRS1	1741
MECOM	1687
PSMD10	1559
XIAP	1407
UBA52	1121
REST	865
RPS6KB2	700
HDAC1	587
IL33	445
AKT2	433
MLST8	376
ATN1	234
CD86	-14
FRK	-24
TRAF6	-229
PPP2R1B	-241
ERBB3	-472
TNKS2	-499
MBD3	-528
PSMA4	-616
PPP2R5E	-680
RRAGB	-713
TSC2	-804
PSMC5	-863
AGO3	-1011
STUB1	-1032
CREB1	-1378
GATAD2B	-1759
RBBP4	-1870
NRG4	-1875
PIP4K2A	-2365
SUZ12	-2409
MTA1	-3005
PSMB8	-3076
FGFR4	-3293
FRS2	-3433
CD19	-3843
RING1	-4063
FGF7	-4247
CHD4	-4515
TNRC6B	-4518
CBX2	-4617
PTENP1	-5280
PSMA3	-5285
FGFR1	-5352
TNRC6A	-5613
PSMB10	-5735
SCMH1	-5839
TRIB3	-5843
PSMA5	-6053
PSME4	-6087
SALL4	-6112
FOXO6	-6367
FGF23	-6622
USP13	-6737
NR4A1	-6756
CD80	-6841
RPS27A	-6938
MTA2	-7317
TRAT1	-7535
PSMA8	-7606
PIP4K2B	-7788
PHC3	-8152
CDKN1B	-8207
PHC1	-8402
PDGFB	-8577
FGF22	-8607
PML	-8693
TNKS	-8738
FGF9	-8761
SRC	-8820
ESR1	-9122
PSMC4	-9127
ESR2	-9250
EED	-9348
KDM1A	-9430
MTA3	-9433
ICOS	-9434
FOXO1	-9465
PIK3R1	-9505
RICTOR	-9670
CHD3	-9737
EZH2	-9741
MTOR	-9767
BMI1	-9829
PSME1	-9991
CD28	-10202
PSME2	-10336
MIR25	-10350
RPTOR	-10464
OTUD3	-10763
TP53	-10893
KIT	-11004
THEM4	-11069
CNOT6L	-11248
PPP2R5C	-11265
PSMB9	-11324
PIP4K2C	-11371
PDGFRB	-11545
FYN	-11675
FGFR2	-11785
TNRC6C	-11828
LCK	-11838
AKT3	-11849
PHLPP2	-11948
PRR5	-11985
MOV10	-11991
PIK3R3	-12015
RBBP7	-12155
ERBB2	-12320

---

Toll Like Receptor 3 (TLR3) Cascade

Toll Like Receptor 3 (TLR3) Cascade

	1240
set	Toll Like Receptor 3 (TLR3) Cascade
setSize	92
pANOVA	6.7e-07
s.dist	0.3
p.adjustANOVA	9.34e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
DUSP3	9280
UBE2D1	9187
APP	9177
MAPK14	9104
MAP2K1	9063
MAPK3	8953
MAP2K6	8887
MAP2K3	8748
UBE2D3	8640
NOD2	8442
MAPKAPK3	8382
PPP2CA	8234
MEF2A	8009
CHUK	7966
PPP2CB	7712
RPS6KA1	7695
TANK	7502
MAPK1	7493

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A12	9515
NKIRAS2	9353
DUSP3	9280
UBE2D1	9187
APP	9177
MAPK14	9104
MAP2K1	9063
MAPK3	8953
MAP2K6	8887
MAP2K3	8748
UBE2D3	8640
NOD2	8442
MAPKAPK3	8382
PPP2CA	8234
MEF2A	8009
CHUK	7966
PPP2CB	7712
RPS6KA1	7695
TANK	7502
MAPK1	7493
TAB2	6964
MAP2K4	6866
NFKBIA	6807
UBB	6639
TICAM1	6307
NFKB1	6277
FBXW11	6196
MAP3K8	6160
IRAK1	6131
ATF1	5706
TAB1	5681
FADD	5641
UBE2V1	5637
TNIP2	5552
FOS	5460
IKBKG	5377
IKBKE	4715
BIRC2	4692
UBE2D2	4657
PPP2R1A	4589
UBC	4439
DUSP6	4357
MAPK10	4325
SKP1	4287
RIPK3	4217
MAPKAPK2	4054
MAPK11	3826
JUN	3722
TBK1	3229
TAB3	3160
RPS6KA2	3087
RPS6KA3	2973
PPP2R5D	2421
MAP3K7	2395
ATF2	2085
UBE2N	1936
MAP2K7	1654
AGER	1294
VRK3	1281
UBA52	1121
ELK1	1040
RIPK2	1025
NKIRAS1	375
NFKBIB	-152
TRAF6	-229
PPP2R1B	-241
HMGB1	-252
MEF2C	-293
NFKB2	-1165
MAPK7	-1337
CREB1	-1378
RELA	-1803
DUSP7	-3211
BTRC	-4924
IKBKB	-5386
S100B	-5457
TRAF3	-5576
DUSP4	-6287
RPS27A	-6938
MAPK9	-7068
IRF3	-8517
IRF7	-8657
MAPK8	-9428
IRAK2	-9548
RIPK1	-11074
BIRC3	-11125
CUL1	-11330
CASP8	-11336
TLR3	-11525
RPS6KA5	-11594
SARM1	-12134
NOD1	-12263

---

Signaling by NOTCH4

Signaling by NOTCH4

	1118
set	Signaling by NOTCH4
setSize	79
pANOVA	6.95e-07
s.dist	0.323
p.adjustANOVA	9.58e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TACC3	9331
NCSTN	9186
MAML3	8957
ADAM10	8791
RBPJ	8770
JAG1	8743
PSMB7	8485
PSMD4	8402
PSME3	8251
PSMB5	8101
PSEN1	7961
PSMD6	7846
PSMD9	7620
PSMD2	7411
PSMA1	7329
PSMD1	7241
PSMB3	7171
PSMA7	7096
PSMC1	7021
PSMB6	6813

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TACC3	9331
NCSTN	9186
MAML3	8957
ADAM10	8791
RBPJ	8770
JAG1	8743
PSMB7	8485
PSMD4	8402
PSME3	8251
PSMB5	8101
PSEN1	7961
PSMD6	7846
PSMD9	7620
PSMD2	7411
PSMA1	7329
PSMD1	7241
PSMB3	7171
PSMA7	7096
PSMC1	7021
PSMB6	6813
PSMF1	6659
UBB	6639
PSMC6	6635
PSMD12	6556
APH1B	6280
PSMD11	6231
EP300	6129
PSMA6	5970
PSMD7	5963
PSMD13	5948
PSMD8	5757
PSENEN	5735
YWHAZ	5624
MAML1	5404
PSMA2	5339
NOTCH2	5272
SNW1	5201
NOTCH1	4704
PSMD3	4618
UBC	4439
SEM1	4348
SKP1	4287
APH1A	4133
PSMB2	4084
RBX1	3934
AKT1	3614
PSMD5	3426
CREBBP	3423
PSMB1	3374
PSMD14	2611
PSMC2	2598
PSMB4	2523
PSMC3	1976
PSMD10	1559
UBA52	1121
ACTA2	-429
MAML2	-582
PSMA4	-616
PSMC5	-863
KAT2B	-2414
PSMB8	-3076
NOTCH4	-5229
PSMA3	-5285
MAMLD1	-5584
PSMB10	-5735
PSMA5	-6053
FBXW7	-6600
RPS27A	-6938
FLT4	-7216
PSEN2	-7718
HES1	-8266
PSMC4	-9127
HEY2	-9752
PSME1	-9991
PSME2	-10336
KAT2A	-10771
PSMB9	-11324
CUL1	-11330
SMAD3	-11745

---

Signaling by MET

Signaling by MET

	1108
set	Signaling by MET
setSize	61
pANOVA	7.13e-07
s.dist	0.367
p.adjustANOVA	9.74e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LAMC1	9387
GRB2	9304
TNS3	9262
CRK	8906
HGF	8863
RAC1	8793
SPINT1	8446
SPINT2	8206
STAT3	8098
RAB4A	7941
PTPRJ	7783
SH3GL1	7625
PTPN2	7615
LAMB3	7497
CBL	7480
RAP1A	7305
UBB	6639
USP8	6418
SH3KBP1	6173
STAM2	6159

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LAMC1	9387
GRB2	9304
TNS3	9262
CRK	8906
HGF	8863
RAC1	8793
SPINT1	8446
SPINT2	8206
STAT3	8098
RAB4A	7941
PTPRJ	7783
SH3GL1	7625
PTPN2	7615
LAMB3	7497
CBL	7480
RAP1A	7305
UBB	6639
USP8	6418
SH3KBP1	6173
STAM2	6159
LAMB1	5966
RANBP9	5813
PTPN1	5722
GAB1	5679
NRAS	5363
PTPN11	5314
PIK3CA	4629
HGS	4513
PTK2	4462
UBC	4439
ITGA2	4168
SHC1	4161
EPS15	4138
CRKL	3966
GGA3	3816
KRAS	3702
RAP1B	3206
RAB4B	3137
HPN	2625
RANBP10	2553
ARF6	1377
STAM	1285
UBA52	1121
LAMB2	501
TNS4	100
ITGB1	-94
LAMA1	-1044
LAMC3	-2016
LAMA4	-2252
DOCK7	-2369
LAMA5	-3263
HRAS	-3382
SOS1	-5700
MUC20	-5962
RPS27A	-6938
SRC	-8820
PIK3R1	-9505
RAPGEF1	-9826
LAMA2	-9911
LRIG1	-10389
ITGA3	-10750

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.0.3 (2020-10-10)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 20.04.2 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.9.0
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.9.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.2.0               GGally_2.1.1               
##  [3] beeswarm_0.3.1              gtools_3.8.2               
##  [5] echarts4r_0.4.0             topconfects_1.6.0          
##  [7] limma_3.46.0                eulerr_6.1.0               
##  [9] mitch_1.2.2                 MASS_7.3-53.1              
## [11] fgsea_1.16.0                gplots_3.1.1               
## [13] DESeq2_1.30.0               SummarizedExperiment_1.20.0
## [15] Biobase_2.50.0              MatrixGenerics_1.2.0       
## [17] matrixStats_0.58.0          GenomicRanges_1.42.0       
## [19] GenomeInfoDb_1.26.0         IRanges_2.24.0             
## [21] S4Vectors_0.28.0            BiocGenerics_0.36.0        
## [23] reshape2_1.4.4              forcats_0.5.1              
## [25] stringr_1.4.0               dplyr_1.0.5                
## [27] purrr_0.3.4                 readr_1.4.0                
## [29] tidyr_1.1.3                 tibble_3.1.0               
## [31] ggplot2_3.3.3               tidyverse_1.3.0            
## [33] zoo_1.8-9                  
## 
## loaded via a namespace (and not attached):
##   [1] colorspace_2.0-0       ellipsis_0.3.1         rprojroot_2.0.2       
##   [4] XVector_0.30.0         fs_1.5.0               rstudioapi_0.13       
##   [7] farver_2.1.0           bit64_4.0.5            AnnotationDbi_1.52.0  
##  [10] fansi_0.4.2            lubridate_1.7.10       xml2_1.3.2            
##  [13] splines_4.0.3          cachem_1.0.4           geneplotter_1.68.0    
##  [16] knitr_1.31             polyclip_1.10-0        jsonlite_1.7.2        
##  [19] broom_0.7.5            annotate_1.68.0        dbplyr_2.1.0          
##  [22] shiny_1.6.0            compiler_4.0.3         httr_1.4.2            
##  [25] backports_1.2.1        assertthat_0.2.1       Matrix_1.3-2          
##  [28] fastmap_1.1.0          cli_2.3.1              later_1.1.0.1         
##  [31] htmltools_0.5.1.1      tools_4.0.3            gtable_0.3.0          
##  [34] glue_1.4.2             GenomeInfoDbData_1.2.4 fastmatch_1.1-0       
##  [37] Rcpp_1.0.6             cellranger_1.1.0       jquerylib_0.1.3       
##  [40] vctrs_0.3.6            polylabelr_0.2.0       xfun_0.22             
##  [43] ps_1.6.0               testthat_3.0.2         rvest_1.0.0           
##  [46] mime_0.10              lifecycle_1.0.0        XML_3.99-0.6          
##  [49] zlibbioc_1.36.0        scales_1.1.1           promises_1.2.0.1      
##  [52] hms_1.0.0              RColorBrewer_1.1-2     yaml_2.2.1            
##  [55] memoise_2.0.0          gridExtra_2.3          sass_0.3.1            
##  [58] reshape_0.8.8          stringi_1.5.3          RSQLite_2.2.4         
##  [61] highr_0.8              genefilter_1.72.0      desc_1.3.0            
##  [64] caTools_1.18.1         BiocParallel_1.24.1    rlang_0.4.10          
##  [67] pkgconfig_2.0.3        bitops_1.0-6           evaluate_0.14         
##  [70] lattice_0.20-41        labeling_0.4.2         htmlwidgets_1.5.3     
##  [73] bit_4.0.4              tidyselect_1.1.0       plyr_1.8.6            
##  [76] magrittr_2.0.1         R6_2.5.0               generics_0.1.0        
##  [79] DelayedArray_0.16.0    DBI_1.1.1              pillar_1.5.1          
##  [82] haven_2.3.1            withr_2.4.1            survival_3.2-10       
##  [85] RCurl_1.98-1.3         modelr_0.1.8           crayon_1.4.1          
##  [88] KernSmooth_2.23-18     utf8_1.2.1             rmarkdown_2.7         
##  [91] locfit_1.5-9.4         grid_4.0.3             readxl_1.3.1          
##  [94] data.table_1.14.0      blob_1.2.1             reprex_1.0.0          
##  [97] digest_0.6.27          xtable_1.8-4           httpuv_1.5.5          
## [100] munsell_0.5.0          bslib_0.2.4

END of report