date generated: 2020-11-11

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

##             low CRP    high CRP
## A1BG      1.0864505  2.93660576
## A1BG-AS1  0.2363048  0.81097593
## A1CF      0.6265346  0.20979938
## A2M      -1.1565132 -4.19066691
## A2M-AS1  -1.1830767 -3.99635746
## A2ML1    -0.3033644 -0.09097114

Here are some metrics about the input data profile:

Profile metrics
Profile metrics
num_genes_in_profile 21404
duplicated_genes_present 0
num_profile_genes_in_sets 8378
num_profile_genes_not_in_sets 13026
profile_pearson_correl 0.66054
profile_spearman_correl 0.61532

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt

Gene sets metrics
Gene sets metrics
num_genesets 2408
num_genesets_excluded 1045
num_genesets_included 1363

Gene sets by quadrant


Number of significant gene sets (FDR<0.05)= 639

Interactive enrichment scatterplot

All sets with FDR<0.05. Try hovering over the points.

Top N sets irrespective of FDR. Try hovering over the points.

A heatmap of S values for top results


A plot of effect size versus significance


Significance is the -log2(p.adjustMANOVA) and effect size is the s.dist which is the hypotenuse of the s scores.

Results table

Top N= 50 gene sets

set setSize pMANOVA p.adjustMANOVA s.dist s.low.CRP s.high.CRP p.low.CRP p.high.CRP
Neutrophil degranulation 456 0.00e+00 0.00e+00 0.770 0.4910 0.593 9.83e-73 0.00e+00
Innate Immune System 963 6.13e-91 4.18e-88 0.487 0.3190 0.368 1.70e-63 7.54e-84
Immune System 1885 2.77e-52 1.26e-49 0.264 0.1580 0.211 4.26e-30 4.62e-52
Membrane Trafficking 555 5.94e-44 2.02e-41 0.399 0.1940 0.349 5.33e-15 5.80e-45
Signal Transduction 1869 1.00e-35 2.74e-33 0.198 0.0903 0.176 1.01e-10 2.34e-36
Vesicle-mediated transport 644 3.04e-33 6.90e-31 0.347 0.2070 0.279 3.64e-19 1.28e-33
Metabolism 1758 1.90e-30 3.71e-28 0.197 0.1030 0.168 5.85e-13 1.29e-31
Metabolism of proteins 1706 1.53e-28 2.61e-26 0.191 0.0967 0.165 3.22e-11 1.16e-29
Post-translational protein modification 1183 2.92e-28 4.42e-26 0.215 0.0971 0.192 1.84e-08 7.00e-29
Hemostasis 542 1.80e-22 2.45e-20 0.319 0.2170 0.233 4.53e-18 1.78e-20
Platelet activation, signaling and aggregation 219 2.66e-22 3.30e-20 0.465 0.2520 0.390 1.25e-10 2.28e-23
Signaling by Receptor Tyrosine Kinases 408 7.11e-22 8.08e-20 0.327 0.1610 0.284 2.19e-08 6.76e-23
Signaling by Interleukins 385 1.98e-21 2.08e-19 0.359 0.2200 0.284 1.37e-13 1.03e-21
Metabolism of lipids 619 2.02e-20 1.97e-18 0.249 0.1130 0.222 1.62e-06 3.83e-21
Disease 1339 2.21e-19 2.01e-17 0.179 0.0971 0.151 2.52e-09 1.99e-20
Asparagine N-linked glycosylation 269 4.80e-18 4.09e-16 0.367 0.1870 0.316 1.32e-07 4.39e-19
Scavenging of heme from plasma 70 2.16e-17 1.73e-15 0.376 0.2500 -0.280 2.92e-04 5.05e-05
Response to elevated platelet cytosolic Ca2+ 108 8.50e-17 6.44e-15 0.599 0.3800 0.463 9.02e-12 8.21e-17
Toll-like Receptor Cascades 143 4.51e-16 3.11e-14 0.495 0.2860 0.404 3.68e-09 6.79e-17
Platelet degranulation 104 4.56e-16 3.11e-14 0.598 0.3830 0.459 1.42e-11 5.60e-16
Diseases of signal transduction by growth factor receptors and second messengers 339 7.52e-16 4.88e-14 0.300 0.1450 0.263 4.51e-06 8.91e-17
CD22 mediated BCR regulation 58 1.55e-15 9.58e-14 0.400 0.1970 -0.348 9.56e-03 4.59e-06
Creation of C4 and C2 activators 70 4.10e-15 2.43e-13 0.359 0.1740 -0.314 1.18e-02 5.41e-06
ER to Golgi Anterograde Transport 129 4.52e-15 2.51e-13 0.480 0.2420 0.414 1.99e-06 4.59e-16
Signaling by NOTCH 182 4.60e-15 2.51e-13 0.405 0.2060 0.349 1.67e-06 4.60e-16
Toll Like Receptor 4 (TLR4) Cascade 121 5.54e-15 2.90e-13 0.511 0.2830 0.425 7.62e-08 6.13e-16
Transport of small molecules 554 6.00e-15 3.03e-13 0.250 0.1540 0.196 5.35e-10 2.54e-15
Classical antibody-mediated complement activation 68 7.31e-15 3.56e-13 0.366 0.1610 -0.328 2.16e-02 2.87e-06
Binding and Uptake of Ligands by Scavenger Receptors 91 9.23e-15 4.34e-13 0.314 0.2800 -0.142 3.95e-06 1.90e-02
Interleukin-1 signaling 97 1.45e-14 6.57e-13 0.561 0.3090 0.468 1.50e-07 1.57e-15
FCGR activation 75 3.32e-14 1.43e-12 0.342 0.1430 -0.311 3.22e-02 3.24e-06
Initial triggering of complement 77 3.37e-14 1.43e-12 0.332 0.1580 -0.292 1.65e-02 9.18e-06
Role of LAT2/NTAL/LAB on calcium mobilization 73 4.31e-14 1.78e-12 0.329 0.2300 -0.236 6.84e-04 4.98e-04
MyD88:MAL(TIRAP) cascade initiated on plasma membrane 92 5.35e-14 1.97e-12 0.566 0.3150 0.470 1.75e-07 6.24e-15
Toll Like Receptor 2 (TLR2) Cascade 92 5.35e-14 1.97e-12 0.566 0.3150 0.470 1.75e-07 6.24e-15
Toll Like Receptor TLR1:TLR2 Cascade 92 5.35e-14 1.97e-12 0.566 0.3150 0.470 1.75e-07 6.24e-15
Toll Like Receptor TLR6:TLR2 Cascade 92 5.35e-14 1.97e-12 0.566 0.3150 0.470 1.75e-07 6.24e-15
Transport to the Golgi and subsequent modification 155 7.98e-14 2.86e-12 0.401 0.1810 0.358 9.86e-05 1.43e-14
Clathrin-mediated endocytosis 125 8.48e-14 2.96e-12 0.450 0.2080 0.399 6.07e-05 1.32e-14
Signaling by Rho GTPases 364 9.12e-14 3.11e-12 0.269 0.1290 0.236 2.29e-05 1.15e-14
Developmental Biology 726 1.61e-13 5.35e-12 0.179 0.0723 0.163 9.06e-04 6.48e-14
Interleukin-1 family signaling 124 4.75e-13 1.54e-11 0.459 0.2400 0.391 4.08e-06 4.94e-14
Antigen processing-Cross presentation 97 7.58e-13 2.40e-11 0.509 0.2580 0.438 1.08e-05 8.20e-14
RHO GTPase Effectors 248 1.12e-12 3.47e-11 0.319 0.1650 0.273 7.43e-06 1.19e-13
Regulation of Complement cascade 93 1.56e-12 4.61e-11 0.274 0.2030 -0.185 7.10e-04 2.09e-03
Complement cascade 97 1.56e-12 4.61e-11 0.269 0.2010 -0.179 6.33e-04 2.33e-03
Role of phospholipids in phagocytosis 87 3.18e-12 9.22e-11 0.290 0.1350 -0.257 3.01e-02 3.51e-05
Intra-Golgi and retrograde Golgi-to-ER traffic 179 7.30e-12 2.07e-10 0.351 0.1670 0.309 1.16e-04 1.00e-12
Signaling by WNT 253 9.98e-12 2.74e-10 0.283 0.1210 0.256 9.01e-04 2.45e-12
Class I MHC mediated antigen processing & presentation 347 1.00e-11 2.74e-10 0.236 0.0937 0.217 2.72e-03 4.12e-12


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pMANOVA p.adjustMANOVA s.dist s.low.CRP s.high.CRP p.low.CRP p.high.CRP
Neutrophil degranulation 456 1.26e-111 1.72e-108 0.77000 0.491000 5.93e-01 9.83e-73 2.07e-105
Innate Immune System 963 6.13e-91 4.18e-88 0.48700 0.319000 3.68e-01 1.70e-63 7.54e-84
Immune System 1885 2.77e-52 1.26e-49 0.26400 0.158000 2.11e-01 4.26e-30 4.62e-52
Membrane Trafficking 555 5.94e-44 2.02e-41 0.39900 0.194000 3.49e-01 5.33e-15 5.80e-45
Signal Transduction 1869 1.00e-35 2.74e-33 0.19800 0.090300 1.76e-01 1.01e-10 2.34e-36
Vesicle-mediated transport 644 3.04e-33 6.90e-31 0.34700 0.207000 2.79e-01 3.64e-19 1.28e-33
Metabolism 1758 1.90e-30 3.71e-28 0.19700 0.103000 1.68e-01 5.85e-13 1.29e-31
Metabolism of proteins 1706 1.53e-28 2.61e-26 0.19100 0.096700 1.65e-01 3.22e-11 1.16e-29
Post-translational protein modification 1183 2.92e-28 4.42e-26 0.21500 0.097100 1.92e-01 1.84e-08 7.00e-29
Hemostasis 542 1.80e-22 2.45e-20 0.31900 0.217000 2.33e-01 4.53e-18 1.78e-20
Platelet activation, signaling and aggregation 219 2.66e-22 3.30e-20 0.46500 0.252000 3.90e-01 1.25e-10 2.28e-23
Signaling by Receptor Tyrosine Kinases 408 7.11e-22 8.08e-20 0.32700 0.161000 2.84e-01 2.19e-08 6.76e-23
Signaling by Interleukins 385 1.98e-21 2.08e-19 0.35900 0.220000 2.84e-01 1.37e-13 1.03e-21
Metabolism of lipids 619 2.02e-20 1.97e-18 0.24900 0.113000 2.22e-01 1.62e-06 3.83e-21
Disease 1339 2.21e-19 2.01e-17 0.17900 0.097100 1.51e-01 2.52e-09 1.99e-20
Asparagine N-linked glycosylation 269 4.80e-18 4.09e-16 0.36700 0.187000 3.16e-01 1.32e-07 4.39e-19
Scavenging of heme from plasma 70 2.16e-17 1.73e-15 0.37600 0.250000 -2.80e-01 2.92e-04 5.05e-05
Response to elevated platelet cytosolic Ca2+ 108 8.50e-17 6.44e-15 0.59900 0.380000 4.63e-01 9.02e-12 8.21e-17
Toll-like Receptor Cascades 143 4.51e-16 3.11e-14 0.49500 0.286000 4.04e-01 3.68e-09 6.79e-17
Platelet degranulation 104 4.56e-16 3.11e-14 0.59800 0.383000 4.59e-01 1.42e-11 5.60e-16
Diseases of signal transduction by growth factor receptors and second messengers 339 7.52e-16 4.88e-14 0.30000 0.145000 2.63e-01 4.51e-06 8.91e-17
CD22 mediated BCR regulation 58 1.55e-15 9.58e-14 0.40000 0.197000 -3.48e-01 9.56e-03 4.59e-06
Creation of C4 and C2 activators 70 4.10e-15 2.43e-13 0.35900 0.174000 -3.14e-01 1.18e-02 5.41e-06
ER to Golgi Anterograde Transport 129 4.52e-15 2.51e-13 0.48000 0.242000 4.14e-01 1.99e-06 4.59e-16
Signaling by NOTCH 182 4.60e-15 2.51e-13 0.40500 0.206000 3.49e-01 1.67e-06 4.60e-16
Toll Like Receptor 4 (TLR4) Cascade 121 5.54e-15 2.90e-13 0.51100 0.283000 4.25e-01 7.62e-08 6.13e-16
Transport of small molecules 554 6.00e-15 3.03e-13 0.25000 0.154000 1.96e-01 5.35e-10 2.54e-15
Classical antibody-mediated complement activation 68 7.31e-15 3.56e-13 0.36600 0.161000 -3.28e-01 2.16e-02 2.87e-06
Binding and Uptake of Ligands by Scavenger Receptors 91 9.23e-15 4.34e-13 0.31400 0.280000 -1.42e-01 3.95e-06 1.90e-02
Interleukin-1 signaling 97 1.45e-14 6.57e-13 0.56100 0.309000 4.68e-01 1.50e-07 1.57e-15
FCGR activation 75 3.32e-14 1.43e-12 0.34200 0.143000 -3.11e-01 3.22e-02 3.24e-06
Initial triggering of complement 77 3.37e-14 1.43e-12 0.33200 0.158000 -2.92e-01 1.65e-02 9.18e-06
Role of LAT2/NTAL/LAB on calcium mobilization 73 4.31e-14 1.78e-12 0.32900 0.230000 -2.36e-01 6.84e-04 4.98e-04
MyD88:MAL(TIRAP) cascade initiated on plasma membrane 92 5.35e-14 1.97e-12 0.56600 0.315000 4.70e-01 1.75e-07 6.24e-15
Toll Like Receptor 2 (TLR2) Cascade 92 5.35e-14 1.97e-12 0.56600 0.315000 4.70e-01 1.75e-07 6.24e-15
Toll Like Receptor TLR1:TLR2 Cascade 92 5.35e-14 1.97e-12 0.56600 0.315000 4.70e-01 1.75e-07 6.24e-15
Toll Like Receptor TLR6:TLR2 Cascade 92 5.35e-14 1.97e-12 0.56600 0.315000 4.70e-01 1.75e-07 6.24e-15
Transport to the Golgi and subsequent modification 155 7.98e-14 2.86e-12 0.40100 0.181000 3.58e-01 9.86e-05 1.43e-14
Clathrin-mediated endocytosis 125 8.48e-14 2.96e-12 0.45000 0.208000 3.99e-01 6.07e-05 1.32e-14
Signaling by Rho GTPases 364 9.12e-14 3.11e-12 0.26900 0.129000 2.36e-01 2.29e-05 1.15e-14
Developmental Biology 726 1.61e-13 5.35e-12 0.17900 0.072300 1.63e-01 9.06e-04 6.48e-14
Interleukin-1 family signaling 124 4.75e-13 1.54e-11 0.45900 0.240000 3.91e-01 4.08e-06 4.94e-14
Antigen processing-Cross presentation 97 7.58e-13 2.40e-11 0.50900 0.258000 4.38e-01 1.08e-05 8.20e-14
RHO GTPase Effectors 248 1.12e-12 3.47e-11 0.31900 0.165000 2.73e-01 7.43e-06 1.19e-13
Regulation of Complement cascade 93 1.56e-12 4.61e-11 0.27400 0.203000 -1.85e-01 7.10e-04 2.09e-03
Complement cascade 97 1.56e-12 4.61e-11 0.26900 0.201000 -1.79e-01 6.33e-04 2.33e-03
Role of phospholipids in phagocytosis 87 3.18e-12 9.22e-11 0.29000 0.135000 -2.57e-01 3.01e-02 3.51e-05
Intra-Golgi and retrograde Golgi-to-ER traffic 179 7.30e-12 2.07e-10 0.35100 0.167000 3.09e-01 1.16e-04 1.00e-12
Signaling by WNT 253 9.98e-12 2.74e-10 0.28300 0.121000 2.56e-01 9.01e-04 2.45e-12
Class I MHC mediated antigen processing & presentation 347 1.00e-11 2.74e-10 0.23600 0.093700 2.17e-01 2.72e-03 4.12e-12
Toll Like Receptor 7/8 (TLR7/8) Cascade 89 1.30e-11 3.47e-10 0.52100 0.290000 4.33e-01 2.18e-06 1.63e-12
rRNA processing in the nucleus and cytosol 189 1.39e-11 3.64e-10 0.32800 -0.145000 -2.95e-01 5.89e-04 2.82e-12
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 87 1.44e-11 3.71e-10 0.52700 0.295000 4.37e-01 2.02e-06 1.85e-12
Programmed Cell Death 179 2.12e-11 5.28e-10 0.37000 0.215000 3.01e-01 7.04e-07 3.45e-12
Signaling by NTRKs 114 2.13e-11 5.28e-10 0.45400 0.250000 3.79e-01 3.88e-06 2.57e-12
MyD88 dependent cascade initiated on endosome 88 3.62e-11 8.80e-10 0.51200 0.282000 4.27e-01 4.63e-06 4.44e-12
Major pathway of rRNA processing in the nucleolus and cytosol 179 5.49e-11 1.31e-09 0.32700 -0.144000 -2.94e-01 8.97e-04 1.14e-11
Toll Like Receptor 9 (TLR9) Cascade 92 5.72e-11 1.34e-09 0.49900 0.280000 4.13e-01 3.48e-06 7.57e-12
Translocation of ZAP-70 to Immunological synapse 24 7.25e-11 1.67e-09 1.02000 -0.679000 -7.59e-01 8.22e-09 1.20e-10
Cellular responses to external stimuli 503 9.71e-11 2.20e-09 0.21100 0.116000 1.77e-01 9.00e-06 1.18e-11
RHO GTPases Activate WASPs and WAVEs 35 1.35e-10 3.02e-09 0.81700 0.502000 6.45e-01 2.79e-07 4.06e-11
EPH-Ephrin signaling 78 1.61e-10 3.53e-09 0.53700 0.315000 4.36e-01 1.52e-06 2.84e-11
MyD88 cascade initiated on plasma membrane 82 1.85e-10 3.89e-09 0.50600 0.271000 4.27e-01 2.15e-05 2.19e-11
Toll Like Receptor 10 (TLR10) Cascade 82 1.85e-10 3.89e-09 0.50600 0.271000 4.27e-01 2.15e-05 2.19e-11
Toll Like Receptor 5 (TLR5) Cascade 82 1.85e-10 3.89e-09 0.50600 0.271000 4.27e-01 2.15e-05 2.19e-11
COPI-mediated anterograde transport 78 2.53e-10 5.18e-09 0.50400 0.255000 4.35e-01 9.81e-05 3.06e-11
FCERI mediated Ca+2 mobilization 88 2.55e-10 5.18e-09 0.26000 0.136000 -2.21e-01 2.78e-02 3.34e-04
FCERI mediated MAPK activation 89 2.70e-10 5.39e-09 0.25800 0.221000 -1.33e-01 3.06e-04 3.02e-02
Infectious disease 773 2.73e-10 5.39e-09 0.17400 0.106000 1.38e-01 5.11e-07 7.52e-11
Signaling by NTRK1 (TRKA) 100 2.82e-10 5.48e-09 0.45100 0.237000 3.84e-01 4.17e-05 3.32e-11
Autophagy 123 3.51e-10 6.74e-09 0.42000 0.244000 3.42e-01 2.86e-06 5.90e-11
Cellular responses to stress 497 3.56e-10 6.75e-09 0.20600 0.113000 1.73e-01 1.71e-05 4.43e-11
rRNA processing 218 4.60e-10 8.59e-09 0.30900 -0.171000 -2.57e-01 1.37e-05 5.96e-11
Apoptosis 167 4.84e-10 8.92e-09 0.35700 0.207000 2.92e-01 4.01e-06 7.84e-11
Intracellular signaling by second messengers 271 5.16e-10 9.38e-09 0.23900 0.088400 2.22e-01 1.23e-02 2.91e-10
Golgi-to-ER retrograde transport 111 5.73e-10 1.03e-08 0.42200 0.222000 3.58e-01 5.20e-05 6.86e-11
ER-Phagosome pathway 82 5.95e-10 1.05e-08 0.46900 0.221000 4.14e-01 5.53e-04 9.00e-11
Rab regulation of trafficking 120 7.63e-10 1.33e-08 0.36600 0.148000 3.34e-01 4.99e-03 2.43e-10
Cellular response to hypoxia 71 1.53e-09 2.64e-08 0.49300 0.233000 4.35e-01 6.98e-04 2.31e-10
MyD88-independent TLR4 cascade 96 1.60e-09 2.69e-08 0.43900 0.227000 3.76e-01 1.22e-04 1.97e-10
TRIF(TICAM1)-mediated TLR4 signaling 96 1.60e-09 2.69e-08 0.43900 0.227000 3.76e-01 1.22e-04 1.97e-10
The citric acid (TCA) cycle and respiratory electron transport 172 2.28e-09 3.79e-08 0.31400 0.148000 2.77e-01 8.13e-04 3.49e-10
PIP3 activates AKT signaling 239 3.36e-09 5.51e-08 0.24700 0.095800 2.28e-01 1.08e-02 1.32e-09
PPARA activates gene expression 104 3.49e-09 5.66e-08 0.37700 0.152000 3.46e-01 7.52e-03 1.13e-09
Cargo recognition for clathrin-mediated endocytosis 88 4.01e-09 6.43e-08 0.42200 0.187000 3.79e-01 2.47e-03 8.01e-10
RHO GTPases activate PKNs 47 4.15e-09 6.57e-08 0.62000 0.332000 5.23e-01 8.24e-05 5.25e-10
Signaling by Nuclear Receptors 214 5.26e-09 8.24e-08 0.28900 0.153000 2.45e-01 1.17e-04 6.64e-10
RUNX1 regulates transcription of genes involved in differentiation of HSCs 82 6.85e-09 1.06e-07 0.46700 0.254000 3.91e-01 6.84e-05 9.03e-10
FCGR3A-mediated IL10 synthesis 98 8.66e-09 1.33e-07 0.22400 0.124000 -1.87e-01 3.37e-02 1.40e-03
Regulation of lipid metabolism by PPARalpha 106 8.95e-09 1.35e-07 0.35900 0.138000 3.32e-01 1.42e-02 3.61e-09
Amyloid fiber formation 51 1.27e-08 1.90e-07 0.60300 0.365000 4.80e-01 6.35e-06 3.05e-09
ROS and RNS production in phagocytes 31 1.32e-08 1.96e-07 0.79300 0.577000 5.45e-01 2.73e-08 1.53e-07
PCP/CE pathway 86 1.48e-08 2.16e-07 0.38900 0.145000 3.61e-01 2.01e-02 6.83e-09
TCF dependent signaling in response to WNT 165 1.56e-08 2.27e-07 0.28000 0.103000 2.60e-01 2.27e-02 7.76e-09
Metabolism of carbohydrates 241 1.94e-08 2.79e-07 0.22800 0.081000 2.13e-01 3.03e-02 1.14e-08
Cytokine Signaling in Immune system 733 2.08e-08 2.95e-07 0.15200 0.079500 1.29e-01 2.46e-04 2.71e-09
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 83 2.23e-08 3.13e-07 0.23700 0.134000 -1.96e-01 3.54e-02 2.07e-03
COPI-independent Golgi-to-ER retrograde traffic 33 2.25e-08 3.13e-07 0.72900 0.426000 5.92e-01 2.29e-05 4.03e-09
trans-Golgi Network Vesicle Budding 69 2.75e-08 3.79e-07 0.47700 0.243000 4.10e-01 4.71e-04 3.67e-09
COPII-mediated vesicle transport 65 2.79e-08 3.81e-07 0.49300 0.254000 4.23e-01 4.00e-04 3.70e-09
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 124 2.98e-08 4.03e-07 0.33900 0.152000 3.03e-01 3.52e-03 5.68e-09
Deubiquitination 240 3.64e-08 4.86e-07 0.24600 0.115000 2.18e-01 2.16e-03 5.99e-09
PD-1 signaling 28 3.99e-08 5.28e-07 0.80500 -0.535000 -6.02e-01 9.47e-07 3.51e-08
RAB GEFs exchange GTP for GDP on RABs 87 4.32e-08 5.66e-07 0.41900 0.213000 3.61e-01 6.05e-04 5.86e-09
ESR-mediated signaling 159 4.45e-08 5.78e-07 0.33000 0.200000 2.63e-01 1.36e-05 1.05e-08
Cell surface interactions at the vascular wall 172 5.16e-08 6.64e-07 0.22900 0.225000 4.18e-02 3.63e-07 3.44e-01
Detoxification of Reactive Oxygen Species 31 5.24e-08 6.67e-07 0.72800 0.417000 5.97e-01 5.93e-05 8.44e-09
CLEC7A (Dectin-1) signaling 96 5.48e-08 6.92e-07 0.40700 0.222000 3.41e-01 1.66e-04 7.64e-09
PTEN Regulation 138 6.97e-08 8.71e-07 0.29500 0.110000 2.73e-01 2.55e-02 2.96e-08
Regulation of actin dynamics for phagocytic cup formation 122 7.10e-08 8.80e-07 0.28400 0.275000 7.26e-02 1.59e-07 1.66e-01
Signaling by NOTCH4 78 7.97e-08 9.79e-07 0.42600 0.206000 3.73e-01 1.65e-03 1.20e-08
UCH proteinases 86 8.05e-08 9.80e-07 0.31900 0.059300 3.14e-01 3.42e-01 4.96e-07
C-type lectin receptors (CLRs) 128 9.15e-08 1.10e-06 0.35300 0.201000 2.90e-01 8.79e-05 1.46e-08
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 64 9.91e-08 1.18e-06 0.46600 0.223000 4.09e-01 2.03e-03 1.54e-08
Toll Like Receptor 3 (TLR3) Cascade 92 1.14e-07 1.35e-06 0.38400 0.181000 3.39e-01 2.71e-03 1.86e-08
Interleukin-4 and Interleukin-13 signaling 92 1.59e-07 1.87e-06 0.41400 0.334000 2.45e-01 3.19e-08 4.71e-05
tRNA processing in the mitochondrion 32 1.76e-07 2.05e-06 0.41000 -0.405000 6.65e-02 7.36e-05 5.15e-01
Macroautophagy 109 2.06e-07 2.37e-06 0.36900 0.205000 3.07e-01 2.14e-04 3.09e-08
Regulation of PTEN stability and activity 66 2.07e-07 2.37e-06 0.43500 0.192000 3.90e-01 7.10e-03 4.23e-08
Phosphorylation of CD3 and TCR zeta chains 27 2.11e-07 2.39e-06 0.78300 -0.564000 -5.42e-01 3.81e-07 1.07e-06
Defective CFTR causes cystic fibrosis 58 2.79e-07 3.15e-06 0.47800 0.235000 4.16e-01 2.00e-03 4.20e-08
MAP kinase activation 63 3.08e-07 3.44e-06 0.46100 0.231000 3.98e-01 1.51e-03 4.49e-08
Beta-catenin independent WNT signaling 136 4.08e-07 4.53e-06 0.30600 0.147000 2.68e-01 3.15e-03 6.53e-08
Post-translational protein phosphorylation 68 4.25e-07 4.63e-06 0.46100 0.264000 3.78e-01 1.62e-04 7.22e-08
EPHB-mediated forward signaling 32 4.26e-07 4.63e-06 0.70200 0.482000 5.11e-01 2.40e-06 5.70e-07
SARS-CoV Infections 140 4.28e-07 4.63e-06 0.27500 0.102000 2.56e-01 3.73e-02 1.77e-07
FLT3 Signaling 242 4.37e-07 4.68e-06 0.21700 0.089500 1.98e-01 1.65e-02 1.16e-07
Nervous system development 470 4.39e-07 4.68e-06 0.15500 0.062500 1.42e-01 2.02e-02 1.28e-07
Generation of second messenger molecules 38 4.43e-07 4.68e-06 0.63600 -0.406000 -4.89e-01 1.45e-05 1.82e-07
Axon guidance 451 4.60e-07 4.83e-06 0.16300 0.071100 1.46e-01 9.71e-03 9.82e-08
Respiratory electron transport 101 4.86e-07 5.06e-06 0.34300 0.153000 3.07e-01 7.94e-03 9.65e-08
MAP2K and MAPK activation 34 5.69e-07 5.88e-06 0.64700 0.374000 5.27e-01 1.57e-04 1.01e-07
FCGR3A-mediated phagocytosis 120 5.89e-07 5.95e-06 0.25500 0.250000 4.90e-02 2.26e-06 3.54e-01
Leishmania phagocytosis 120 5.89e-07 5.95e-06 0.25500 0.250000 4.90e-02 2.26e-06 3.54e-01
Parasite infection 120 5.89e-07 5.95e-06 0.25500 0.250000 4.90e-02 2.26e-06 3.54e-01
Pre-NOTCH Expression and Processing 65 6.05e-07 6.05e-06 0.44000 0.216000 3.83e-01 2.55e-03 9.27e-08
Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 53 6.09e-07 6.05e-06 0.49800 0.259000 4.25e-01 1.09e-03 8.79e-08
Neddylation 217 6.19e-07 6.12e-06 0.21800 0.080500 2.03e-01 4.10e-02 2.57e-07
Interleukin-17 signaling 68 6.70e-07 6.57e-06 0.42700 0.208000 3.73e-01 3.00e-03 1.05e-07
MAPK family signaling cascades 267 6.89e-07 6.71e-06 0.22100 0.114000 1.89e-01 1.29e-03 1.00e-07
MAPK1/MAPK3 signaling 233 7.58e-07 7.33e-06 0.22300 0.099300 2.00e-01 9.02e-03 1.52e-07
VEGFA-VEGFR2 Pathway 90 7.70e-07 7.39e-06 0.36800 0.178000 3.22e-01 3.61e-03 1.24e-07
IRAK4 deficiency (TLR2/4) 10 8.78e-07 8.31e-06 1.22000 0.845000 8.86e-01 3.74e-06 1.20e-06
MyD88 deficiency (TLR2/4) 10 8.78e-07 8.31e-06 1.22000 0.845000 8.86e-01 3.74e-06 1.20e-06
Signaling by BRAF and RAF fusions 57 9.29e-07 8.73e-06 0.50700 0.328000 3.87e-01 1.84e-05 4.28e-07
Transcriptional regulation of granulopoiesis 46 9.38e-07 8.75e-06 0.57100 0.403000 4.04e-01 2.21e-06 2.18e-06
ABC transporter disorders 69 1.04e-06 9.65e-06 0.41900 0.207000 3.65e-01 2.93e-03 1.61e-07
Phospholipid metabolism 184 1.17e-06 1.08e-05 0.26300 0.138000 2.23e-01 1.20e-03 1.73e-07
Cargo concentration in the ER 30 1.44e-06 1.32e-05 0.68100 0.423000 5.34e-01 6.09e-05 4.19e-07
Oncogenic MAPK signaling 73 1.58e-06 1.43e-05 0.43100 0.259000 3.45e-01 1.27e-04 3.54e-07
Fcgamma receptor (FCGR) dependent phagocytosis 146 1.58e-06 1.43e-05 0.24600 0.233000 7.84e-02 1.11e-06 1.02e-01
Hedgehog ligand biogenesis 58 1.59e-06 1.43e-05 0.46100 0.242000 3.92e-01 1.43e-03 2.38e-07
Cross-presentation of soluble exogenous antigens (endosomes) 47 1.71e-06 1.52e-05 0.51100 0.269000 4.34e-01 1.42e-03 2.56e-07
Chromatin modifying enzymes 217 1.75e-06 1.54e-05 0.13700 -0.041900 1.31e-01 2.87e-01 9.16e-04
Chromatin organization 217 1.75e-06 1.54e-05 0.13700 -0.041900 1.31e-01 2.87e-01 9.16e-04
RAB geranylgeranylation 61 1.95e-06 1.70e-05 0.46100 0.264000 3.77e-01 3.62e-04 3.41e-07
Transcriptional regulation of white adipocyte differentiation 77 1.97e-06 1.71e-05 0.33500 0.105000 3.18e-01 1.10e-01 1.41e-06
Hh mutants abrogate ligand secretion 54 2.00e-06 1.73e-05 0.47100 0.245000 4.03e-01 1.86e-03 3.01e-07
Leishmania infection 243 2.02e-06 1.73e-05 0.22200 0.191000 1.14e-01 3.05e-07 2.20e-03
HDACs deacetylate histones 47 2.10e-06 1.78e-05 0.47300 0.206000 4.25e-01 1.45e-02 4.54e-07
RAF/MAP kinase cascade 228 2.10e-06 1.78e-05 0.21100 0.087300 1.92e-01 2.32e-02 5.48e-07
Regulation of mRNA stability by proteins that bind AU-rich elements 87 2.15e-06 1.81e-05 0.39100 0.237000 3.12e-01 1.32e-04 5.06e-07
AUF1 (hnRNP D0) binds and destabilizes mRNA 53 2.28e-06 1.90e-05 0.47300 0.246000 4.05e-01 1.96e-03 3.44e-07
Regulation of ornithine decarboxylase (ODC) 49 2.32e-06 1.93e-05 0.50700 0.285000 4.19e-01 5.52e-04 3.84e-07
Degradation of DVL 54 2.36e-06 1.95e-05 0.45500 0.219000 3.99e-01 5.32e-03 3.92e-07
Iron uptake and transport 52 2.37e-06 1.95e-05 0.51600 0.385000 3.43e-01 1.57e-06 1.84e-05
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 78 2.39e-06 1.95e-05 0.40900 0.242000 3.29e-01 2.22e-04 4.88e-07
FCERI mediated NF-kB activation 136 2.60e-06 2.11e-05 0.21500 0.213000 2.58e-02 1.74e-05 6.04e-01
Smooth Muscle Contraction 30 2.63e-06 2.12e-05 0.64800 0.371000 5.32e-01 4.36e-04 4.62e-07
Antimicrobial peptides 33 2.72e-06 2.18e-05 0.62600 0.503000 3.73e-01 5.78e-07 2.08e-04
Endosomal Sorting Complex Required For Transport (ESCRT) 29 2.76e-06 2.20e-05 0.64000 0.339000 5.43e-01 1.56e-03 4.21e-07
Negative regulation of NOTCH4 signaling 54 3.14e-06 2.48e-05 0.45400 0.224000 3.95e-01 4.45e-03 5.04e-07
Transcriptional regulation by RUNX1 184 3.25e-06 2.56e-05 0.21800 0.074200 2.05e-01 8.24e-02 1.69e-06
DNA strand elongation 32 3.38e-06 2.65e-05 0.63100 -0.377000 -5.06e-01 2.23e-04 7.32e-07
Antigen processing: Ubiquitination & Proteasome degradation 286 3.40e-06 2.65e-05 0.16600 0.045900 1.59e-01 1.82e-01 3.58e-06
Degradation of GLI2 by the proteasome 56 3.79e-06 2.92e-05 0.45600 0.243000 3.86e-01 1.62e-03 5.86e-07
GLI3 is processed to GLI3R by the proteasome 56 3.79e-06 2.92e-05 0.45600 0.243000 3.86e-01 1.62e-03 5.86e-07
Regulation of activated PAK-2p34 by proteasome mediated degradation 48 3.81e-06 2.92e-05 0.48500 0.248000 4.17e-01 2.90e-03 5.90e-07
Degradation of GLI1 by the proteasome 57 3.87e-06 2.95e-05 0.44600 0.230000 3.82e-01 2.66e-03 5.98e-07
Signaling by MET 60 4.00e-06 3.03e-05 0.46300 0.287000 3.63e-01 1.19e-04 1.14e-06
Golgi Associated Vesicle Biogenesis 55 4.03e-06 3.04e-05 0.46600 0.260000 3.87e-01 8.66e-04 6.62e-07
Degradation of beta-catenin by the destruction complex 83 4.19e-06 3.12e-05 0.34800 0.153000 3.12e-01 1.59e-02 8.86e-07
Interferon alpha/beta signaling 57 4.21e-06 3.12e-05 0.42300 -0.377000 -1.92e-01 8.21e-07 1.23e-02
Senescence-Associated Secretory Phenotype (SASP) 66 4.21e-06 3.12e-05 0.38600 0.166000 3.49e-01 1.96e-02 9.59e-07
Integration of energy metabolism 86 4.32e-06 3.18e-05 0.38400 0.235000 3.04e-01 1.64e-04 1.10e-06
Signaling by VEGF 97 4.56e-06 3.34e-05 0.31600 0.134000 2.86e-01 2.21e-02 1.08e-06
Activation of NF-kappaB in B cells 65 4.60e-06 3.36e-05 0.40500 0.196000 3.54e-01 6.28e-03 7.73e-07
RNA Polymerase I Promoter Opening 19 4.75e-06 3.44e-05 0.81400 0.499000 6.43e-01 1.63e-04 1.24e-06
Generic Transcription Pathway 1078 4.82e-06 3.46e-05 0.10800 -0.088800 -6.19e-02 8.57e-07 6.01e-04
Budding and maturation of HIV virion 26 4.82e-06 3.46e-05 0.65100 0.331000 5.60e-01 3.46e-03 7.57e-07
Protein ubiquitination 72 4.98e-06 3.55e-05 0.41300 0.243000 3.33e-01 3.59e-04 1.01e-06
TBC/RABGAPs 45 5.00e-06 3.55e-05 0.39700 0.095000 3.85e-01 2.70e-01 7.65e-06
L1CAM interactions 83 5.12e-06 3.62e-05 0.37300 0.203000 3.13e-01 1.35e-03 8.17e-07
Signaling by high-kinase activity BRAF mutants 31 5.20e-06 3.65e-05 0.63000 0.376000 5.05e-01 2.88e-04 1.13e-06
rRNA modification in the nucleus and cytosol 59 5.77e-06 4.03e-05 0.40700 -0.180000 -3.65e-01 1.65e-02 1.21e-06
Vif-mediated degradation of APOBEC3G 52 6.37e-06 4.43e-05 0.45700 0.234000 3.92e-01 3.47e-03 1.01e-06
Dectin-1 mediated noncanonical NF-kB signaling 58 6.49e-06 4.49e-05 0.43300 0.223000 3.71e-01 3.31e-03 1.02e-06
Cellular Senescence 144 6.90e-06 4.75e-05 0.25900 0.114000 2.32e-01 1.85e-02 1.48e-06
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism 12 7.06e-06 4.81e-05 1.02000 0.656000 7.81e-01 8.39e-05 2.80e-06
alpha-linolenic acid (ALA) metabolism 12 7.06e-06 4.81e-05 1.02000 0.656000 7.81e-01 8.39e-05 2.80e-06
NIK-->noncanonical NF-kB signaling 57 7.40e-06 5.01e-05 0.44200 0.238000 3.72e-01 1.89e-03 1.18e-06
Signaling by RAF1 mutants 34 7.43e-06 5.01e-05 0.58900 0.345000 4.77e-01 4.96e-04 1.47e-06
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 52 8.37e-06 5.62e-05 0.44500 0.220000 3.87e-01 6.06e-03 1.39e-06
Regulation of TP53 Activity through Acetylation 29 8.63e-06 5.77e-05 0.40000 -0.400000 1.33e-02 1.92e-04 9.01e-01
Regulation of Apoptosis 51 9.67e-06 6.43e-05 0.46200 0.249000 3.89e-01 2.09e-03 1.56e-06
Insulin receptor recycling 21 1.06e-05 7.03e-05 0.76600 0.535000 5.49e-01 2.22e-05 1.32e-05
Activation of ATR in response to replication stress 36 1.08e-05 7.09e-05 0.55000 -0.301000 -4.60e-01 1.78e-03 1.78e-06
Diseases associated with the TLR signaling cascade 23 1.11e-05 7.23e-05 0.72500 0.476000 5.48e-01 7.78e-05 5.43e-06
Diseases of Immune System 23 1.11e-05 7.23e-05 0.72500 0.476000 5.48e-01 7.78e-05 5.43e-06
Regulation of TLR by endogenous ligand 11 1.12e-05 7.28e-05 1.05000 0.770000 7.20e-01 9.70e-06 3.51e-05
Paradoxical activation of RAF signaling by kinase inactive BRAF 38 1.15e-05 7.30e-05 0.54500 0.316000 4.44e-01 7.37e-04 2.20e-06
Signaling by RAS mutants 38 1.15e-05 7.30e-05 0.54500 0.316000 4.44e-01 7.37e-04 2.20e-06
Signaling by moderate kinase activity BRAF mutants 38 1.15e-05 7.30e-05 0.54500 0.316000 4.44e-01 7.37e-04 2.20e-06
Signaling downstream of RAS mutants 38 1.15e-05 7.30e-05 0.54500 0.316000 4.44e-01 7.37e-04 2.20e-06
Extracellular matrix organization 215 1.18e-05 7.47e-05 0.23700 0.152000 1.81e-01 1.22e-04 4.54e-06
Hedgehog 'on' state 74 1.26e-05 7.92e-05 0.36200 0.173000 3.18e-01 1.02e-02 2.24e-06
Ub-specific processing proteases 169 1.26e-05 7.92e-05 0.25700 0.147000 2.11e-01 1.01e-03 2.30e-06
The role of GTSE1 in G2/M progression after G2 checkpoint 58 1.33e-05 8.31e-05 0.41900 0.215000 3.60e-01 4.69e-03 2.17e-06
Fc epsilon receptor (FCERI) signaling 189 1.33e-05 8.31e-05 0.21100 0.194000 8.32e-02 4.04e-06 4.86e-02
Selenocysteine synthesis 91 1.36e-05 8.41e-05 0.35800 -0.223000 -2.80e-01 2.39e-04 3.94e-06
Glycerophospholipid biosynthesis 106 1.39e-05 8.60e-05 0.33800 0.234000 2.43e-01 3.09e-05 1.52e-05
Opioid Signalling 75 1.44e-05 8.82e-05 0.37800 0.209000 3.15e-01 1.71e-03 2.44e-06
RHO GTPases Activate NADPH Oxidases 21 1.52e-05 9.29e-05 0.73300 0.442000 5.84e-01 4.58e-04 3.52e-06
Glycosaminoglycan metabolism 92 1.53e-05 9.32e-05 0.24800 0.038200 2.45e-01 5.26e-01 4.75e-05
Activation of the pre-replicative complex 32 1.67e-05 1.01e-04 0.57500 -0.321000 -4.78e-01 1.69e-03 2.89e-06
EGFR downregulation 26 1.85e-05 1.12e-04 0.57200 0.240000 5.19e-01 3.39e-02 4.58e-06
Transferrin endocytosis and recycling 26 1.93e-05 1.16e-04 0.67000 0.457000 4.89e-01 5.48e-05 1.56e-05
Pausing and recovery of Tat-mediated HIV elongation 30 2.00e-05 1.19e-04 0.32500 -0.118000 3.03e-01 2.64e-01 4.10e-03
Tat-mediated HIV elongation arrest and recovery 30 2.00e-05 1.19e-04 0.32500 -0.118000 3.03e-01 2.64e-01 4.10e-03
Vpu mediated degradation of CD4 50 2.05e-05 1.22e-04 0.44500 0.232000 3.80e-01 4.52e-03 3.38e-06
Metabolism of polyamines 57 2.19e-05 1.29e-04 0.44200 0.276000 3.46e-01 3.18e-04 6.38e-06
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 50 2.44e-05 1.42e-04 0.44400 0.235000 3.77e-01 4.00e-03 4.05e-06
p53-Independent DNA Damage Response 50 2.44e-05 1.42e-04 0.44400 0.235000 3.77e-01 4.00e-03 4.05e-06
p53-Independent G1/S DNA damage checkpoint 50 2.44e-05 1.42e-04 0.44400 0.235000 3.77e-01 4.00e-03 4.05e-06
SARS-CoV-2 Infection 63 2.45e-05 1.42e-04 0.33600 0.110000 3.18e-01 1.32e-01 1.30e-05
Regulation of RUNX3 expression and activity 55 2.63e-05 1.52e-04 0.39200 0.170000 3.53e-01 2.90e-02 5.93e-06
Pre-NOTCH Processing in Golgi 18 2.80e-05 1.61e-04 0.52200 0.047900 5.19e-01 7.25e-01 1.36e-04
Ubiquitin-dependent degradation of Cyclin D 50 2.81e-05 1.61e-04 0.42800 0.209000 3.73e-01 1.05e-02 4.95e-06
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 72 2.89e-05 1.65e-04 0.34900 0.161000 3.09e-01 1.82e-02 5.64e-06
Nuclear Events (kinase and transcription factor activation) 53 2.93e-05 1.66e-04 0.38100 0.146000 3.52e-01 6.56e-02 9.45e-06
HIV elongation arrest and recovery 32 2.99e-05 1.68e-04 0.30800 -0.115000 2.85e-01 2.59e-01 5.25e-03
Pausing and recovery of HIV elongation 32 2.99e-05 1.68e-04 0.30800 -0.115000 2.85e-01 2.59e-01 5.25e-03
MAPK6/MAPK4 signaling 82 3.09e-05 1.73e-04 0.36400 0.230000 2.82e-01 3.14e-04 1.00e-05
Gene expression (Transcription) 1325 3.15e-05 1.76e-04 0.09340 -0.072000 -5.95e-02 1.09e-05 2.77e-04
Sealing of the nuclear envelope (NE) by ESCRT-III 25 3.17e-05 1.76e-04 0.52800 0.175000 4.98e-01 1.31e-01 1.60e-05
Erythrocytes take up carbon dioxide and release oxygen 11 3.19e-05 1.76e-04 1.00000 0.741000 6.77e-01 2.08e-05 1.02e-04
O2/CO2 exchange in erythrocytes 11 3.19e-05 1.76e-04 1.00000 0.741000 6.77e-01 2.08e-05 1.02e-04
HIV Infection 224 3.25e-05 1.79e-04 0.19600 0.088300 1.75e-01 2.28e-02 6.70e-06
Downstream signaling events of B Cell Receptor (BCR) 79 3.27e-05 1.79e-04 0.32900 0.149000 2.93e-01 2.19e-02 6.65e-06
GPVI-mediated activation cascade 31 3.29e-05 1.79e-04 0.41200 0.063200 4.07e-01 5.42e-01 8.70e-05
Oxidative Stress Induced Senescence 79 3.32e-05 1.80e-04 0.37100 0.240000 2.84e-01 2.31e-04 1.29e-05
Signal amplification 28 3.40e-05 1.84e-04 0.62700 0.464000 4.22e-01 2.16e-05 1.09e-04
HSP90 chaperone cycle for steroid hormone receptors (SHR) 36 3.45e-05 1.86e-04 0.53100 0.308000 4.33e-01 1.41e-03 6.76e-06
Pre-NOTCH Transcription and Translation 49 3.64e-05 1.95e-04 0.45200 0.257000 3.72e-01 1.85e-03 6.78e-06
Hyaluronan uptake and degradation 12 3.64e-05 1.95e-04 0.94100 0.591000 7.32e-01 3.93e-04 1.12e-05
Protein folding 90 3.93e-05 2.09e-04 0.29700 0.124000 2.69e-01 4.19e-02 9.89e-06
Transcriptional regulation by RUNX2 99 5.28e-05 2.79e-04 0.27300 0.107000 2.51e-01 6.46e-02 1.57e-05
Translocation of SLC2A4 (GLUT4) to the plasma membrane 48 5.29e-05 2.79e-04 0.44800 0.254000 3.69e-01 2.32e-03 9.94e-06
ABC-family proteins mediated transport 92 5.43e-05 2.86e-04 0.31400 0.165000 2.67e-01 6.13e-03 9.34e-06
XBP1(S) activates chaperone genes 47 5.47e-05 2.87e-04 0.35300 0.090400 3.41e-01 2.84e-01 5.16e-05
Metabolism of steroids 116 5.72e-05 2.99e-04 0.26000 0.113000 2.34e-01 3.49e-02 1.30e-05
IRE1alpha activates chaperones 49 5.77e-05 3.00e-04 0.34300 0.085100 3.32e-01 3.02e-01 5.79e-05
Adaptive Immune System 753 5.84e-05 3.03e-04 0.09470 0.031000 8.95e-02 1.48e-01 2.93e-05
Chaperonin-mediated protein folding 84 6.02e-05 3.11e-04 0.32200 0.163000 2.78e-01 9.84e-03 1.06e-05
Recycling pathway of L1 26 6.08e-05 3.13e-04 0.50700 0.174000 4.76e-01 1.24e-01 2.65e-05
Asymmetric localization of PCP proteins 60 6.21e-05 3.18e-04 0.34500 0.133000 3.19e-01 7.40e-02 1.95e-05
Peptide chain elongation 87 6.28e-05 3.21e-04 0.33900 -0.209000 -2.67e-01 7.58e-04 1.68e-05
SCF-beta-TrCP mediated degradation of Emi1 53 6.63e-05 3.37e-04 0.39500 0.189000 3.47e-01 1.76e-02 1.25e-05
Autodegradation of Cdh1 by Cdh1:APC/C 64 7.19e-05 3.63e-04 0.36800 0.190000 3.16e-01 8.57e-03 1.26e-05
Platelet Aggregation (Plug Formation) 28 7.19e-05 3.63e-04 0.57500 0.325000 4.75e-01 2.93e-03 1.35e-05
Eukaryotic Translation Elongation 92 7.43e-05 3.74e-04 0.32800 -0.204000 -2.56e-01 7.33e-04 2.12e-05
Degradation of AXIN 53 7.88e-05 3.95e-04 0.38900 0.183000 3.43e-01 2.13e-02 1.54e-05
APC/C:Cdc20 mediated degradation of Securin 66 7.95e-05 3.97e-04 0.35700 0.179000 3.09e-01 1.20e-02 1.42e-05
Estrogen-dependent gene expression 98 8.66e-05 4.31e-04 0.29900 0.159000 2.53e-01 6.47e-03 1.53e-05
RHO GTPases Activate ROCKs 18 8.93e-05 4.43e-04 0.66300 0.313000 5.85e-01 2.13e-02 1.74e-05
Signaling by NOTCH1 66 8.99e-05 4.44e-04 0.36500 0.197000 3.07e-01 5.71e-03 1.60e-05
Autodegradation of the E3 ubiquitin ligase COP1 49 9.07e-05 4.46e-04 0.40800 0.200000 3.55e-01 1.54e-02 1.67e-05
E3 ubiquitin ligases ubiquitinate target proteins 52 9.22e-05 4.52e-04 0.40400 0.210000 3.45e-01 8.87e-03 1.63e-05
Inhibition of DNA recombination at telomere 35 1.01e-04 4.91e-04 0.45100 0.186000 4.11e-01 5.63e-02 2.63e-05
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 11 1.02e-04 4.96e-04 0.84100 0.395000 7.42e-01 2.32e-02 2.01e-05
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 22 1.02e-04 4.96e-04 0.62400 0.333000 5.28e-01 6.91e-03 1.82e-05
Platelet homeostasis 67 1.03e-04 4.98e-04 0.35600 0.187000 3.03e-01 8.06e-03 1.83e-05
MTOR signalling 39 1.11e-04 5.35e-04 0.48400 0.285000 3.91e-01 2.05e-03 2.41e-05
Signaling by EGFR 45 1.13e-04 5.43e-04 0.40000 0.171000 3.61e-01 4.71e-02 2.73e-05
Complex I biogenesis 55 1.14e-04 5.43e-04 0.32800 0.102000 3.12e-01 1.91e-01 6.26e-05
Signaling by Hedgehog 119 1.17e-04 5.58e-04 0.24900 0.110000 2.23e-01 3.80e-02 2.61e-05
Platelet sensitization by LDL 16 1.20e-04 5.68e-04 0.67500 0.298000 6.06e-01 3.92e-02 2.69e-05
Eukaryotic Translation Termination 91 1.20e-04 5.68e-04 0.32300 -0.205000 -2.49e-01 7.40e-04 3.93e-05
Late endosomal microautophagy 29 1.23e-04 5.81e-04 0.53700 0.286000 4.55e-01 7.78e-03 2.21e-05
Signaling by Insulin receptor 59 1.25e-04 5.86e-04 0.40600 0.284000 2.90e-01 1.62e-04 1.19e-04
VLDLR internalisation and degradation 11 1.28e-04 6.00e-04 0.64200 0.095400 6.35e-01 5.84e-01 2.66e-04
DNA methylation 20 1.38e-04 6.42e-04 0.66800 0.395000 5.39e-01 2.21e-03 3.05e-05
Amino acids regulate mTORC1 50 1.38e-04 6.44e-04 0.41600 0.235000 3.43e-01 3.99e-03 2.68e-05
Sphingolipid metabolism 78 1.41e-04 6.55e-04 0.31800 0.158000 2.75e-01 1.56e-02 2.61e-05
RNA Polymerase II Transcription 1197 1.43e-04 6.59e-04 0.08470 -0.072300 -4.41e-02 2.57e-05 1.03e-02
Regulation of cholesterol biosynthesis by SREBP (SREBF) 55 1.46e-04 6.72e-04 0.34400 0.133000 3.18e-01 8.82e-02 4.55e-05
Regulation of RAS by GAPs 66 1.47e-04 6.74e-04 0.31700 0.126000 2.91e-01 7.69e-02 4.27e-05
Uptake and function of anthrax toxins 10 1.57e-04 7.16e-04 0.91500 0.505000 7.63e-01 5.68e-03 2.93e-05
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 51 1.69e-04 7.70e-04 0.42800 0.314000 2.90e-01 1.04e-04 3.36e-04
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 20 1.74e-04 7.90e-04 0.66000 0.392000 5.31e-01 2.42e-03 3.94e-05
Neurodegenerative Diseases 20 1.74e-04 7.90e-04 0.66000 0.392000 5.31e-01 2.42e-03 3.94e-05
Lysosome Vesicle Biogenesis 32 1.86e-04 8.38e-04 0.50200 0.270000 4.23e-01 8.18e-03 3.42e-05
Inflammasomes 20 1.93e-04 8.69e-04 0.63800 0.533000 3.49e-01 3.62e-05 6.81e-03
RHO GTPases activate PAKs 20 1.98e-04 8.89e-04 0.58700 0.260000 5.27e-01 4.44e-02 4.49e-05
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 181 2.01e-04 8.97e-04 0.18100 -0.062100 -1.70e-01 1.50e-01 8.33e-05
tRNA processing 136 2.02e-04 9.01e-04 0.25600 -0.161000 -1.99e-01 1.22e-03 6.13e-05
p130Cas linkage to MAPK signaling for integrins 11 2.21e-04 9.81e-04 0.90800 0.649000 6.35e-01 1.94e-04 2.66e-04
Viral mRNA Translation 87 2.22e-04 9.81e-04 0.31300 -0.187000 -2.51e-01 2.55e-03 5.18e-05
Advanced glycosylation endproduct receptor signaling 12 2.24e-04 9.88e-04 0.80900 0.432000 6.83e-01 9.49e-03 4.15e-05
CDK-mediated phosphorylation and removal of Cdc6 71 2.40e-04 1.05e-03 0.32800 0.171000 2.80e-01 1.29e-02 4.45e-05
N-glycan trimming in the ER and Calnexin/Calreticulin cycle 35 2.44e-04 1.07e-03 0.41600 0.157000 3.85e-01 1.09e-01 8.04e-05
Homologous DNA Pairing and Strand Exchange 42 2.53e-04 1.11e-03 0.42300 -0.217000 -3.63e-01 1.51e-02 4.73e-05
Influenza Viral RNA Transcription and Replication 134 2.59e-04 1.13e-03 0.25000 -0.148000 -2.01e-01 3.09e-03 5.90e-05
Notch-HLH transcription pathway 28 2.62e-04 1.14e-03 0.49700 0.231000 4.40e-01 3.44e-02 5.46e-05
Anti-inflammatory response favouring Leishmania parasite infection 167 2.96e-04 1.28e-03 0.11500 0.099700 -5.75e-02 2.62e-02 2.00e-01
Leishmania parasite growth and survival 167 2.96e-04 1.28e-03 0.11500 0.099700 -5.75e-02 2.62e-02 2.00e-01
Stabilization of p53 54 3.09e-04 1.33e-03 0.37300 0.199000 3.16e-01 1.16e-02 5.82e-05
TP53 Regulates Metabolic Genes 85 3.16e-04 1.35e-03 0.30200 0.168000 2.51e-01 7.32e-03 6.18e-05
Activation of HOX genes during differentiation 69 3.21e-04 1.37e-03 0.26000 0.062300 2.53e-01 3.71e-01 2.80e-04
Activation of anterior HOX genes in hindbrain development during early embryogenesis 69 3.21e-04 1.37e-03 0.26000 0.062300 2.53e-01 3.71e-01 2.80e-04
Synthesis of active ubiquitin: roles of E1 and E2 enzymes 30 3.38e-04 1.43e-03 0.53600 0.380000 3.78e-01 3.17e-04 3.37e-04
MHC class II antigen presentation 101 3.43e-04 1.45e-03 0.24500 0.098700 2.24e-01 8.66e-02 9.66e-05
SARS-CoV-1 Infection 47 3.48e-04 1.47e-03 0.31000 0.069200 3.02e-01 4.12e-01 3.38e-04
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75 3.48e-04 1.47e-03 0.31400 0.165000 2.66e-01 1.34e-02 6.59e-05
Collagen degradation 28 3.55e-04 1.49e-03 0.54000 0.331000 4.26e-01 2.45e-03 9.41e-05
Selenoamino acid metabolism 113 3.57e-04 1.49e-03 0.26000 -0.143000 -2.17e-01 8.43e-03 6.97e-05
RAF activation 32 3.57e-04 1.49e-03 0.45500 0.210000 4.04e-01 4.01e-02 7.66e-05
Sema4D in semaphorin signaling 22 3.76e-04 1.56e-03 0.47500 0.138000 4.55e-01 2.64e-01 2.23e-04
COPI-dependent Golgi-to-ER retrograde traffic 78 3.77e-04 1.56e-03 0.29200 0.135000 2.58e-01 3.89e-02 8.01e-05
M Phase 359 4.01e-04 1.65e-03 0.13500 0.061800 1.21e-01 4.43e-02 8.77e-05
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 93 4.02e-04 1.65e-03 0.28700 -0.164000 -2.36e-01 6.29e-03 8.33e-05
Infection with Mycobacterium tuberculosis 26 4.34e-04 1.78e-03 0.53500 0.297000 4.45e-01 8.74e-03 8.63e-05
Unwinding of DNA 12 4.41e-04 1.81e-03 0.83300 -0.582000 -5.95e-01 4.80e-04 3.55e-04
APC/C:Cdc20 mediated degradation of mitotic proteins 74 4.48e-04 1.82e-03 0.31200 0.167000 2.64e-01 1.30e-02 8.63e-05
Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71 4.48e-04 1.82e-03 0.32500 0.184000 2.68e-01 7.38e-03 9.15e-05
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72 4.50e-04 1.83e-03 0.32200 0.181000 2.67e-01 7.87e-03 9.12e-05
GRB2:SOS provides linkage to MAPK signaling for Integrins 12 4.56e-04 1.84e-03 0.82300 0.627000 5.33e-01 1.71e-04 1.39e-03
Negative regulation of MET activity 18 4.86e-04 1.96e-03 0.64700 0.374000 5.28e-01 6.04e-03 1.05e-04
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function 53 4.94e-04 1.98e-03 0.35500 0.175000 3.09e-01 2.75e-02 9.83e-05
Ion channel transport 133 5.02e-04 2.01e-03 0.23700 0.135000 1.95e-01 7.32e-03 1.05e-04
rRNA processing in the mitochondrion 29 5.07e-04 2.03e-03 0.33600 -0.336000 -1.04e-02 1.75e-03 9.22e-01
Transcriptional regulation by RUNX3 90 5.23e-04 2.08e-03 0.26300 0.119000 2.35e-01 5.11e-02 1.18e-04
Signal transduction by L1 20 5.68e-04 2.26e-03 0.59300 0.320000 4.99e-01 1.31e-02 1.12e-04
Semaphorin interactions 57 5.79e-04 2.29e-03 0.32900 0.150000 2.93e-01 4.96e-02 1.29e-04
Retrograde neurotrophin signalling 12 5.84e-04 2.31e-03 0.68200 0.269000 6.26e-01 1.06e-01 1.73e-04
Mitotic Anaphase 223 5.90e-04 2.32e-03 0.16200 0.067200 1.47e-01 8.36e-02 1.56e-04
Signalling to ERKs 31 5.93e-04 2.33e-03 0.49900 0.311000 3.90e-01 2.72e-03 1.73e-04
Energy dependent regulation of mTOR by LKB1-AMPK 27 6.57e-04 2.57e-03 0.50300 0.269000 4.26e-01 1.57e-02 1.29e-04
Telomere C-strand (Lagging Strand) Synthesis 34 6.69e-04 2.61e-03 0.47300 -0.297000 -3.68e-01 2.70e-03 2.04e-04
G-protein beta:gamma signalling 29 7.26e-04 2.83e-03 0.49200 0.277000 4.06e-01 9.91e-03 1.51e-04
Costimulation by the CD28 family 74 7.37e-04 2.86e-03 0.32000 -0.247000 -2.03e-01 2.39e-04 2.53e-03
Regulation of insulin secretion 60 7.52e-04 2.91e-03 0.36000 0.251000 2.58e-01 7.80e-04 5.51e-04
Presynaptic phase of homologous DNA pairing and strand exchange 39 7.73e-04 2.99e-03 0.39200 -0.181000 -3.48e-01 5.05e-02 1.71e-04
CDT1 association with the CDC6:ORC:origin complex 57 8.03e-04 3.09e-03 0.33700 0.174000 2.89e-01 2.33e-02 1.60e-04
Packaging Of Telomere Ends 20 8.41e-04 3.23e-03 0.56900 0.297000 4.86e-01 2.16e-02 1.68e-04
Hyaluronan metabolism 15 8.47e-04 3.24e-03 0.70200 0.446000 5.43e-01 2.80e-03 2.74e-04
Gap junction trafficking 13 8.55e-04 3.26e-03 0.66000 0.288000 5.94e-01 7.20e-02 2.08e-04
Response of Mtb to phagocytosis 22 8.56e-04 3.26e-03 0.55300 0.304000 4.62e-01 1.36e-02 1.75e-04
Regulation of RUNX2 expression and activity 66 8.78e-04 3.33e-03 0.30600 0.150000 2.66e-01 3.49e-02 1.81e-04
Extra-nuclear estrogen signaling 65 9.00e-04 3.41e-03 0.34000 0.251000 2.30e-01 4.77e-04 1.31e-03
Degradation of the extracellular matrix 78 9.03e-04 3.41e-03 0.29900 0.173000 2.43e-01 8.34e-03 2.01e-04
Integrin signaling 22 9.18e-04 3.45e-03 0.54700 0.296000 4.60e-01 1.62e-02 1.86e-04
SCF(Skp2)-mediated degradation of p27/p21 60 9.28e-04 3.49e-03 0.32500 0.167000 2.79e-01 2.56e-02 1.87e-04
Mitotic Metaphase and Anaphase 224 9.38e-04 3.51e-03 0.15600 0.064700 1.42e-01 9.52e-02 2.52e-04
Rho GTPase cycle 125 9.48e-04 3.54e-03 0.19700 0.068000 1.84e-01 1.89e-01 3.69e-04
Fatty acid metabolism 150 9.61e-04 3.58e-03 0.20600 0.107000 1.76e-01 2.36e-02 1.93e-04
activated TAK1 mediates p38 MAPK activation 19 9.67e-04 3.58e-03 0.58100 0.306000 4.94e-01 2.09e-02 1.95e-04
WNT5A-dependent internalization of FZD4 13 9.68e-04 3.58e-03 0.57800 0.165000 5.54e-01 3.02e-01 5.46e-04
Hedgehog 'off' state 91 9.82e-04 3.63e-03 0.23600 0.089200 2.18e-01 1.41e-01 3.18e-04
Diseases of carbohydrate metabolism 29 9.92e-04 3.65e-03 0.44400 0.203000 3.96e-01 5.89e-02 2.26e-04
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 13 9.94e-04 3.65e-03 0.66900 0.312000 5.92e-01 5.14e-02 2.19e-04
ADP signalling through P2Y purinoceptor 1 21 9.98e-04 3.65e-03 0.59100 0.445000 3.90e-01 4.16e-04 1.99e-03
Response of EIF2AK4 (GCN2) to amino acid deficiency 99 1.00e-03 3.66e-03 0.25800 -0.142000 -2.16e-01 1.48e-02 2.06e-04
Calnexin/calreticulin cycle 26 1.01e-03 3.68e-03 0.47200 0.219000 4.18e-01 5.33e-02 2.25e-04
Disorders of transmembrane transporters 144 1.02e-03 3.71e-03 0.21700 0.123000 1.78e-01 1.07e-02 2.20e-04
Cell recruitment (pro-inflammatory response) 22 1.08e-03 3.92e-03 0.55100 0.453000 3.13e-01 2.35e-04 1.10e-02
Purinergic signaling in leishmaniasis infection 22 1.08e-03 3.92e-03 0.55100 0.453000 3.13e-01 2.35e-04 1.10e-02
ERKs are inactivated 13 1.09e-03 3.94e-03 0.54500 0.121000 5.31e-01 4.49e-01 9.15e-04
p53-Dependent G1 DNA Damage Response 63 1.15e-03 4.11e-03 0.31300 0.161000 2.68e-01 2.74e-02 2.34e-04
p53-Dependent G1/S DNA damage checkpoint 63 1.15e-03 4.11e-03 0.31300 0.161000 2.68e-01 2.74e-02 2.34e-04
Metabolism of non-coding RNA 53 1.19e-03 4.23e-03 0.24600 -0.025600 -2.45e-01 7.48e-01 2.07e-03
snRNP Assembly 53 1.19e-03 4.23e-03 0.24600 -0.025600 -2.45e-01 7.48e-01 2.07e-03
mTORC1-mediated signalling 24 1.23e-03 4.36e-03 0.54900 0.384000 3.92e-01 1.13e-03 8.90e-04
ERK/MAPK targets 22 1.23e-03 4.36e-03 0.48800 0.205000 4.43e-01 9.63e-02 3.25e-04
DARPP-32 events 22 1.24e-03 4.38e-03 0.50100 0.228000 4.47e-01 6.45e-02 2.87e-04
Spry regulation of FGF signaling 16 1.29e-03 4.55e-03 0.59200 0.276000 5.23e-01 5.63e-02 2.88e-04
Platelet Adhesion to exposed collagen 13 1.31e-03 4.62e-03 0.72400 0.572000 4.43e-01 3.56e-04 5.66e-03
Metabolism of nucleotides 86 1.35e-03 4.75e-03 0.23600 0.219000 8.76e-02 4.53e-04 1.60e-01
Disassembly of the destruction complex and recruitment of AXIN to the membrane 29 1.38e-03 4.85e-03 0.38300 0.118000 3.65e-01 2.72e-01 6.70e-04
Signaling by TGF-beta Receptor Complex 72 1.39e-03 4.85e-03 0.25800 0.096800 2.39e-01 1.56e-01 4.56e-04
Fanconi Anemia Pathway 36 1.41e-03 4.92e-03 0.44300 -0.323000 -3.03e-01 8.11e-04 1.64e-03
tRNA modification in the nucleus and cytosol 43 1.42e-03 4.92e-03 0.29400 -0.066000 -2.87e-01 4.54e-01 1.14e-03
TAK1 activates NFkB by phosphorylation and activation of IKKs complex 27 1.43e-03 4.97e-03 0.46000 0.226000 4.01e-01 4.24e-02 3.06e-04
HDMs demethylate histones 22 1.45e-03 5.03e-03 0.32500 -0.044400 3.22e-01 7.19e-01 8.96e-03
G1/S DNA Damage Checkpoints 65 1.49e-03 5.13e-03 0.30900 0.169000 2.58e-01 1.85e-02 3.13e-04
p75 NTR receptor-mediated signalling 88 1.50e-03 5.15e-03 0.24100 0.102000 2.19e-01 9.72e-02 3.92e-04
The NLRP3 inflammasome 15 1.50e-03 5.15e-03 0.67700 0.515000 4.39e-01 5.56e-04 3.22e-03
tRNA processing in the nucleus 59 1.53e-03 5.24e-03 0.27900 -0.101000 -2.60e-01 1.81e-01 5.43e-04
Golgi Cisternae Pericentriolar Stack Reorganization 14 1.58e-03 5.41e-03 0.67900 0.399000 5.49e-01 9.69e-03 3.77e-04
RHO GTPases activate CIT 18 1.61e-03 5.48e-03 0.45500 0.109000 4.42e-01 4.24e-01 1.16e-03
Extension of Telomeres 51 1.76e-03 5.98e-03 0.36500 -0.247000 -2.69e-01 2.25e-03 8.90e-04
Signaling by Erythropoietin 24 1.78e-03 6.04e-03 0.46800 0.213000 4.16e-01 7.02e-02 4.18e-04
Dissolution of Fibrin Clot 12 1.84e-03 6.22e-03 0.75200 0.531000 5.33e-01 1.45e-03 1.40e-03
Formation of ATP by chemiosmotic coupling 18 1.89e-03 6.36e-03 0.54300 0.255000 4.79e-01 6.12e-02 4.28e-04
MAPK targets/ Nuclear events mediated by MAP kinases 31 1.89e-03 6.36e-03 0.42500 0.215000 3.67e-01 3.85e-02 4.02e-04
PI Metabolism 79 1.92e-03 6.42e-03 0.18600 0.007670 1.86e-01 9.06e-01 4.24e-03
Regulation of APC/C activators between G1/S and early anaphase 79 1.92e-03 6.42e-03 0.27200 0.146000 2.30e-01 2.51e-02 4.06e-04
Signaling by GPCR 534 1.93e-03 6.43e-03 0.09090 0.031300 8.53e-02 2.17e-01 7.46e-04
Nucleobase biosynthesis 13 1.93e-03 6.45e-03 0.41800 0.047300 -4.16e-01 7.68e-01 9.46e-03
Formation of a pool of free 40S subunits 99 1.98e-03 6.58e-03 0.24300 -0.130000 -2.05e-01 2.56e-02 4.19e-04
Interferon Signaling 177 1.99e-03 6.59e-03 0.18600 -0.153000 -1.05e-01 4.45e-04 1.55e-02
Aquaporin-mediated transport 38 2.08e-03 6.89e-03 0.41800 0.305000 2.86e-01 1.16e-03 2.26e-03
Resolution of AP sites via the multiple-nucleotide patch replacement pathway 24 2.09e-03 6.90e-03 0.50100 -0.285000 -4.12e-01 1.58e-02 4.70e-04
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane 22 2.11e-03 6.95e-03 0.47200 0.204000 4.26e-01 9.81e-02 5.43e-04
Factors involved in megakaryocyte development and platelet production 116 2.12e-03 6.95e-03 0.22500 0.124000 1.88e-01 2.15e-02 4.57e-04
Glycosphingolipid metabolism 36 2.13e-03 6.95e-03 0.33100 0.099600 3.16e-01 3.01e-01 1.04e-03
Protein localization 157 2.13e-03 6.95e-03 0.18000 0.081100 1.61e-01 7.96e-02 5.13e-04
Activation of gene expression by SREBF (SREBP) 42 2.13e-03 6.96e-03 0.32500 0.120000 3.02e-01 1.77e-01 7.19e-04
AKT phosphorylates targets in the cytosol 14 2.16e-03 7.02e-03 0.54100 0.176000 5.11e-01 2.54e-01 9.21e-04
Lagging Strand Synthesis 20 2.17e-03 7.03e-03 0.51800 -0.254000 -4.51e-01 4.97e-02 4.74e-04
Abortive elongation of HIV-1 transcript in the absence of Tat 23 2.22e-03 7.10e-03 0.28400 -0.088300 2.70e-01 4.64e-01 2.48e-02
Formation of RNA Pol II elongation complex 57 2.23e-03 7.10e-03 0.22600 0.024200 2.25e-01 7.52e-01 3.30e-03
RNA Polymerase II Transcription Elongation 57 2.23e-03 7.10e-03 0.22600 0.024200 2.25e-01 7.52e-01 3.30e-03
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 53 2.23e-03 7.10e-03 0.32600 0.171000 2.77e-01 3.08e-02 4.75e-04
Constitutive Signaling by NOTCH1 PEST Domain Mutants 53 2.23e-03 7.10e-03 0.32600 0.171000 2.77e-01 3.08e-02 4.75e-04
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 53 2.23e-03 7.10e-03 0.32600 0.171000 2.77e-01 3.08e-02 4.75e-04
Signaling by NOTCH1 PEST Domain Mutants in Cancer 53 2.23e-03 7.10e-03 0.32600 0.171000 2.77e-01 3.08e-02 4.75e-04
Signaling by NOTCH1 in Cancer 53 2.23e-03 7.10e-03 0.32600 0.171000 2.77e-01 3.08e-02 4.75e-04
Plasma lipoprotein assembly, remodeling, and clearance 52 2.27e-03 7.20e-03 0.31800 0.154000 2.79e-01 5.50e-02 5.04e-04
Neurotransmitter receptors and postsynaptic signal transmission 123 2.27e-03 7.21e-03 0.21800 0.121000 1.82e-01 2.02e-02 4.99e-04
Thrombin signalling through proteinase activated receptors (PARs) 27 2.29e-03 7.24e-03 0.48900 0.320000 3.69e-01 4.00e-03 8.92e-04
Thromboxane signalling through TP receptor 20 2.32e-03 7.29e-03 0.56300 0.436000 3.56e-01 7.37e-04 5.86e-03
APC/C-mediated degradation of cell cycle proteins 86 2.32e-03 7.29e-03 0.25300 0.130000 2.17e-01 3.77e-02 4.98e-04
Regulation of mitotic cell cycle 86 2.32e-03 7.29e-03 0.25300 0.130000 2.17e-01 3.77e-02 4.98e-04
Signaling by NOTCH3 42 2.36e-03 7.39e-03 0.30900 0.099300 2.93e-01 2.66e-01 1.03e-03
NOTCH1 Intracellular Domain Regulates Transcription 44 2.38e-03 7.44e-03 0.37600 0.231000 2.96e-01 7.89e-03 6.70e-04
Signaling by the B Cell Receptor (BCR) 161 2.47e-03 7.72e-03 0.15200 0.146000 4.21e-02 1.38e-03 3.57e-01
Signaling by Non-Receptor Tyrosine Kinases 47 2.59e-03 8.05e-03 0.34000 0.176000 2.91e-01 3.72e-02 5.59e-04
Signaling by PTK6 47 2.59e-03 8.05e-03 0.34000 0.176000 2.91e-01 3.72e-02 5.59e-04
Sema4D induced cell migration and growth-cone collapse 19 2.65e-03 8.20e-03 0.46800 0.167000 4.38e-01 2.08e-01 9.58e-04
Signaling by Leptin 10 2.94e-03 9.09e-03 0.78900 0.587000 5.27e-01 1.31e-03 3.91e-03
PLC beta mediated events 43 2.98e-03 9.20e-03 0.35400 0.188000 3.01e-01 3.33e-02 6.50e-04
Circadian Clock 67 3.13e-03 9.64e-03 0.23000 0.062900 2.21e-01 3.73e-01 1.74e-03
Interleukin-10 signaling 35 3.16e-03 9.71e-03 0.41500 0.320000 2.65e-01 1.06e-03 6.63e-03
Pentose phosphate pathway 13 3.27e-03 1.00e-02 0.67700 0.425000 5.26e-01 7.94e-03 1.01e-03
Resolution of Abasic Sites (AP sites) 37 3.27e-03 1.00e-02 0.40800 -0.283000 -2.94e-01 2.90e-03 1.95e-03
Influenza Infection 153 3.42e-03 1.04e-02 0.19500 -0.118000 -1.55e-01 1.17e-02 9.20e-04
G-protein mediated events 44 3.59e-03 1.09e-02 0.33400 0.163000 2.92e-01 6.07e-02 8.17e-04
ADP signalling through P2Y purinoceptor 12 18 3.60e-03 1.09e-02 0.56500 0.449000 3.43e-01 9.80e-04 1.18e-02
Transmission across Chemical Synapses 170 3.63e-03 1.10e-02 0.18600 0.117000 1.45e-01 8.33e-03 1.14e-03
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 36 3.64e-03 1.10e-02 0.40400 0.312000 2.58e-01 1.21e-03 7.43e-03
Cleavage of the damaged purine 24 3.69e-03 1.11e-02 0.44800 0.215000 3.93e-01 6.81e-02 8.54e-04
Depurination 24 3.69e-03 1.11e-02 0.44800 0.215000 3.93e-01 6.81e-02 8.54e-04
Recognition and association of DNA glycosylase with site containing an affected purine 24 3.69e-03 1.11e-02 0.44800 0.215000 3.93e-01 6.81e-02 8.54e-04
Regulation of PTEN gene transcription 59 3.84e-03 1.15e-02 0.24700 0.075400 2.35e-01 3.16e-01 1.78e-03
NOTCH4 Activation and Transmission of Signal to the Nucleus 10 3.92e-03 1.17e-02 0.69900 0.346000 6.07e-01 5.78e-02 8.88e-04
MET activates RAP1 and RAC1 10 4.02e-03 1.20e-02 0.76100 0.487000 5.85e-01 7.65e-03 1.37e-03
Interactions of Rev with host cellular proteins 37 4.06e-03 1.21e-02 0.32700 -0.121000 -3.04e-01 2.01e-01 1.37e-03
Cyclin E associated events during G1/S transition 83 4.07e-03 1.21e-02 0.23400 0.106000 2.09e-01 9.41e-02 1.01e-03
N-Glycan antennae elongation 13 4.13e-03 1.22e-02 0.38300 -0.378000 6.09e-02 1.82e-02 7.04e-01
GPCR downstream signalling 489 4.18e-03 1.24e-02 0.09110 0.034100 8.44e-02 1.96e-01 1.39e-03
Constitutive Signaling by AKT1 E17K in Cancer 26 4.24e-03 1.25e-02 0.26500 -0.053900 2.59e-01 6.34e-01 2.23e-02
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression 32 4.24e-03 1.25e-02 0.34800 0.126000 3.24e-01 2.18e-01 1.49e-03
Potential therapeutics for SARS 78 4.28e-03 1.26e-02 0.23800 0.104000 2.13e-01 1.12e-01 1.11e-03
Neuronal System 253 4.30e-03 1.26e-02 0.14100 0.073000 1.21e-01 4.56e-02 9.62e-04
Signaling by TGFB family members 91 4.35e-03 1.27e-02 0.24200 0.138000 1.99e-01 2.32e-02 1.03e-03
Interleukin-3, Interleukin-5 and GM-CSF signaling 40 4.40e-03 1.28e-02 0.34600 0.172000 3.01e-01 6.04e-02 1.00e-03
Beta-catenin phosphorylation cascade 17 4.40e-03 1.28e-02 0.48200 0.182000 4.46e-01 1.94e-01 1.44e-03
Glucagon signaling in metabolic regulation 27 4.50e-03 1.31e-02 0.46000 0.298000 3.50e-01 7.36e-03 1.64e-03
Vasopressin regulates renal water homeostasis via Aquaporins 34 4.56e-03 1.32e-02 0.41300 0.294000 2.91e-01 3.05e-03 3.30e-03
HCMV Infection 96 4.71e-03 1.36e-02 0.24300 0.156000 1.86e-01 8.23e-03 1.64e-03
Synthesis of PIPs at the plasma membrane 52 4.81e-03 1.39e-02 0.22400 0.027800 2.22e-01 7.29e-01 5.54e-03
Trafficking of GluR2-containing AMPA receptors 12 4.83e-03 1.39e-02 0.55400 0.191000 5.19e-01 2.52e-01 1.83e-03
CD28 dependent PI3K/Akt signaling 22 4.85e-03 1.39e-02 0.45400 -0.400000 -2.14e-01 1.16e-03 8.26e-02
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 113 4.86e-03 1.39e-02 0.22300 -0.144000 -1.71e-01 8.12e-03 1.72e-03
Nonsense-Mediated Decay (NMD) 113 4.86e-03 1.39e-02 0.22300 -0.144000 -1.71e-01 8.12e-03 1.72e-03
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15 5.03e-03 1.44e-02 0.60900 0.390000 4.68e-01 8.96e-03 1.72e-03
Signaling by WNT in cancer 30 5.11e-03 1.46e-02 0.22200 -0.095900 2.00e-01 3.63e-01 5.76e-02
Glycogen metabolism 23 5.14e-03 1.46e-02 0.44200 0.210000 3.89e-01 8.13e-02 1.23e-03
Citric acid cycle (TCA cycle) 22 5.38e-03 1.53e-02 0.37400 0.093500 3.63e-01 4.48e-01 3.24e-03
G beta:gamma signalling through CDC42 17 5.40e-03 1.53e-02 0.55500 0.448000 3.28e-01 1.39e-03 1.90e-02
Post-chaperonin tubulin folding pathway 19 5.49e-03 1.55e-02 0.36700 0.047600 3.64e-01 7.19e-01 5.99e-03
Selective autophagy 57 5.52e-03 1.55e-02 0.31400 0.216000 2.27e-01 4.70e-03 3.05e-03
Rev-mediated nuclear export of HIV RNA 35 5.52e-03 1.55e-02 0.33200 -0.129000 -3.06e-01 1.87e-01 1.74e-03
EPH-ephrin mediated repulsion of cells 39 5.57e-03 1.57e-02 0.33700 0.159000 2.97e-01 8.56e-02 1.35e-03
InlB-mediated entry of Listeria monocytogenes into host cell 12 5.70e-03 1.60e-02 0.65800 0.390000 5.30e-01 1.94e-02 1.48e-03
Unfolded Protein Response (UPR) 87 5.71e-03 1.60e-02 0.22600 0.108000 1.99e-01 8.15e-02 1.37e-03
Cyclin A:Cdk2-associated events at S phase entry 85 5.90e-03 1.65e-02 0.21400 0.085400 1.96e-01 1.73e-01 1.78e-03
HDR through Homologous Recombination (HRR) 66 5.92e-03 1.65e-02 0.26900 -0.143000 -2.28e-01 4.42e-02 1.36e-03
Prolonged ERK activation events 13 6.00e-03 1.67e-02 0.62100 0.354000 5.10e-01 2.70e-02 1.46e-03
NR1H2 and NR1H3-mediated signaling 38 6.03e-03 1.68e-02 0.26900 0.050800 2.64e-01 5.88e-01 4.84e-03
TGF-beta receptor signaling activates SMADs 32 6.08e-03 1.69e-02 0.32500 0.104000 3.08e-01 3.08e-01 2.58e-03
Death Receptor Signalling 131 6.12e-03 1.69e-02 0.18500 0.091200 1.61e-01 7.16e-02 1.44e-03
Growth hormone receptor signaling 20 6.20e-03 1.71e-02 0.52300 0.361000 3.78e-01 5.17e-03 3.41e-03
Assembly of the pre-replicative complex 66 6.21e-03 1.71e-02 0.25300 0.115000 2.25e-01 1.07e-01 1.58e-03
Activated NOTCH1 Transmits Signal to the Nucleus 27 6.24e-03 1.71e-02 0.34000 0.093900 3.27e-01 3.98e-01 3.26e-03
G-protein activation 23 6.57e-03 1.80e-02 0.47700 0.371000 2.99e-01 2.06e-03 1.30e-02
Mucopolysaccharidoses 11 6.64e-03 1.82e-02 0.61500 0.282000 5.47e-01 1.06e-01 1.68e-03
PCNA-Dependent Long Patch Base Excision Repair 21 6.84e-03 1.87e-02 0.46300 -0.237000 -3.98e-01 6.05e-02 1.60e-03
IKK complex recruitment mediated by RIP1 23 6.89e-03 1.88e-02 0.46900 0.284000 3.74e-01 1.84e-02 1.91e-03
Signaling by SCF-KIT 40 6.99e-03 1.90e-02 0.36600 0.254000 2.63e-01 5.39e-03 4.02e-03
NEP/NS2 Interacts with the Cellular Export Machinery 32 7.05e-03 1.92e-02 0.31300 -0.092100 -2.99e-01 3.67e-01 3.37e-03
SUMOylation of immune response proteins 11 7.14e-03 1.94e-02 0.52200 0.139000 5.03e-01 4.25e-01 3.88e-03
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 29 7.17e-03 1.94e-02 0.41800 0.257000 3.30e-01 1.67e-02 2.09e-03
Suppression of phagosomal maturation 12 7.24e-03 1.95e-02 0.51700 0.161000 4.92e-01 3.35e-01 3.19e-03
Mitochondrial biogenesis 88 7.30e-03 1.97e-02 0.24000 0.147000 1.89e-01 1.69e-02 2.12e-03
Effects of PIP2 hydrolysis 24 7.32e-03 1.97e-02 0.41700 -0.368000 -1.96e-01 1.82e-03 9.66e-02
GAB1 signalosome 14 7.36e-03 1.97e-02 0.55500 0.273000 4.83e-01 7.65e-02 1.76e-03
Regulation of TP53 Activity 152 7.37e-03 1.97e-02 0.13700 -0.133000 -3.17e-02 4.70e-03 5.00e-01
Assembly Of The HIV Virion 15 7.55e-03 2.02e-02 0.50500 0.212000 4.58e-01 1.54e-01 2.14e-03
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 32 7.60e-03 2.03e-02 0.40400 0.299000 2.72e-01 3.47e-03 7.65e-03
RNA Polymerase II Pre-transcription Events 78 7.73e-03 2.06e-02 0.19900 0.059100 1.90e-01 3.67e-01 3.63e-03
Intra-Golgi traffic 43 7.74e-03 2.06e-02 0.29800 0.126000 2.70e-01 1.54e-01 2.19e-03
Muscle contraction 135 7.75e-03 2.06e-02 0.17100 0.075400 1.54e-01 1.30e-01 2.07e-03
BBSome-mediated cargo-targeting to cilium 22 8.02e-03 2.12e-02 0.27200 0.050800 -2.68e-01 6.80e-01 2.98e-02
IRAK1 recruits IKK complex 10 8.10e-03 2.14e-02 0.68700 0.393000 5.64e-01 3.12e-02 2.02e-03
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 10 8.10e-03 2.14e-02 0.68700 0.393000 5.64e-01 3.12e-02 2.02e-03
G alpha (z) signalling events 36 8.29e-03 2.18e-02 0.37000 0.227000 2.92e-01 1.85e-02 2.42e-03
Gluconeogenesis 28 8.56e-03 2.25e-02 0.33300 0.104000 3.17e-01 3.41e-01 3.74e-03
Translation of structural proteins 28 8.61e-03 2.26e-02 0.23000 -0.065600 2.20e-01 5.48e-01 4.40e-02
Transcriptional Regulation by TP53 351 8.66e-03 2.27e-02 0.08400 0.013400 8.30e-02 6.67e-01 7.58e-03
Negative regulation of MAPK pathway 42 8.70e-03 2.27e-02 0.24600 0.045600 2.42e-01 6.09e-01 6.75e-03
Formation of HIV-1 elongation complex containing HIV-1 Tat 42 8.76e-03 2.27e-02 0.19800 -0.031200 1.96e-01 7.27e-01 2.81e-02
HIV Transcription Elongation 42 8.76e-03 2.27e-02 0.19800 -0.031200 1.96e-01 7.27e-01 2.81e-02
Tat-mediated elongation of the HIV-1 transcript 42 8.76e-03 2.27e-02 0.19800 -0.031200 1.96e-01 7.27e-01 2.81e-02
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 36 8.78e-03 2.28e-02 0.37500 0.250000 2.79e-01 9.50e-03 3.71e-03
Metabolism of Angiotensinogen to Angiotensins 11 8.86e-03 2.29e-02 0.61200 0.534000 3.00e-01 2.16e-03 8.52e-02
Regulated proteolysis of p75NTR 11 8.94e-03 2.31e-02 0.54700 0.194000 5.12e-01 2.66e-01 3.27e-03
Activation of Matrix Metalloproteinases 23 8.98e-03 2.31e-02 0.45500 0.365000 2.73e-01 2.47e-03 2.36e-02
Peptide hormone metabolism 49 9.38e-03 2.41e-02 0.27000 0.247000 1.10e-01 2.81e-03 1.83e-01
Formation of HIV elongation complex in the absence of HIV Tat 44 9.38e-03 2.41e-02 0.19100 -0.033200 1.88e-01 7.03e-01 3.11e-02
SIRT1 negatively regulates rRNA expression 24 9.93e-03 2.54e-02 0.43900 0.354000 2.60e-01 2.67e-03 2.73e-02
Apoptotic execution phase 45 1.00e-02 2.57e-02 0.31900 0.185000 2.59e-01 3.19e-02 2.61e-03
Transport of the SLBP independent Mature mRNA 35 1.02e-02 2.59e-02 0.25800 -0.038800 -2.55e-01 6.91e-01 9.00e-03
Activation of G protein gated Potassium channels 20 1.03e-02 2.61e-02 0.46700 0.390000 2.56e-01 2.51e-03 4.79e-02
G protein gated Potassium channels 20 1.03e-02 2.61e-02 0.46700 0.390000 2.56e-01 2.51e-03 4.79e-02
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 20 1.03e-02 2.61e-02 0.46700 0.390000 2.56e-01 2.51e-03 4.79e-02
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 16 1.06e-02 2.69e-02 0.36700 0.038000 3.65e-01 7.93e-01 1.14e-02
Heparan sulfate/heparin (HS-GAG) metabolism 37 1.07e-02 2.71e-02 0.21600 -0.016800 2.15e-01 8.60e-01 2.37e-02
Nucleobase catabolism 28 1.07e-02 2.71e-02 0.40000 0.327000 2.31e-01 2.77e-03 3.47e-02
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 32 1.08e-02 2.71e-02 0.26500 0.035100 2.62e-01 7.31e-01 1.02e-02
Formation of the cornified envelope 21 1.08e-02 2.73e-02 0.47400 0.368000 2.99e-01 3.53e-03 1.77e-02
Vpr-mediated nuclear import of PICs 34 1.09e-02 2.74e-02 0.29500 -0.092100 -2.80e-01 3.53e-01 4.72e-03
Cleavage of the damaged pyrimidine 29 1.11e-02 2.77e-02 0.35600 0.159000 3.19e-01 1.38e-01 2.99e-03
Depyrimidination 29 1.11e-02 2.77e-02 0.35600 0.159000 3.19e-01 1.38e-01 2.99e-03
Recognition and association of DNA glycosylase with site containing an affected pyrimidine 29 1.11e-02 2.77e-02 0.35600 0.159000 3.19e-01 1.38e-01 2.99e-03
Processive synthesis on the lagging strand 15 1.12e-02 2.79e-02 0.48600 -0.207000 -4.40e-01 1.65e-01 3.20e-03
Interleukin-12 family signaling 53 1.12e-02 2.79e-02 0.30200 0.212000 2.16e-01 7.53e-03 6.64e-03
ER Quality Control Compartment (ERQC) 21 1.14e-02 2.82e-02 0.44900 0.243000 3.77e-01 5.37e-02 2.79e-03
TNFs bind their physiological receptors 25 1.15e-02 2.85e-02 0.22400 0.097000 -2.02e-01 4.01e-01 8.11e-02
Formation of Fibrin Clot (Clotting Cascade) 26 1.16e-02 2.87e-02 0.43000 0.311000 2.97e-01 6.12e-03 8.80e-03
Transport of the SLBP Dependant Mature mRNA 36 1.16e-02 2.87e-02 0.23600 -0.014800 -2.35e-01 8.78e-01 1.45e-02
TNFR2 non-canonical NF-kB pathway 95 1.16e-02 2.87e-02 0.22300 0.170000 1.43e-01 4.10e-03 1.59e-02
Mitotic G2-G2/M phases 180 1.19e-02 2.92e-02 0.12700 0.039000 1.21e-01 3.67e-01 5.23e-03
Class C/3 (Metabotropic glutamate/pheromone receptors) 11 1.20e-02 2.94e-02 0.39800 0.016700 -3.98e-01 9.24e-01 2.23e-02
Pyruvate metabolism and Citric Acid (TCA) cycle 52 1.21e-02 2.96e-02 0.28500 0.157000 2.38e-01 5.05e-02 3.00e-03
GABA receptor activation 36 1.27e-02 3.10e-02 0.36000 0.242000 2.67e-01 1.19e-02 5.60e-03
HDR through Single Strand Annealing (SSA) 37 1.27e-02 3.11e-02 0.32600 -0.165000 -2.80e-01 8.17e-02 3.15e-03
Cristae formation 31 1.27e-02 3.11e-02 0.36800 0.205000 3.06e-01 4.85e-02 3.21e-03
Gap junction trafficking and regulation 15 1.28e-02 3.11e-02 0.48000 0.207000 4.34e-01 1.65e-01 3.64e-03
Endosomal/Vacuolar pathway 12 1.28e-02 3.11e-02 0.36500 -0.363000 3.86e-02 2.95e-02 8.17e-01
Diseases of programmed cell death 27 1.29e-02 3.12e-02 0.38400 0.199000 3.28e-01 7.39e-02 3.17e-03
Initiation of Nuclear Envelope (NE) Reformation 19 1.31e-02 3.18e-02 0.33300 0.040000 3.31e-01 7.63e-01 1.26e-02
HCMV Late Events 69 1.32e-02 3.18e-02 0.25800 0.168000 1.96e-01 1.57e-02 4.94e-03
Condensation of Prophase Chromosomes 29 1.33e-02 3.22e-02 0.38800 0.231000 3.11e-01 3.12e-02 3.72e-03
GRB2 events in EGFR signaling 10 1.35e-02 3.26e-02 0.67800 0.502000 4.56e-01 5.98e-03 1.25e-02
Synthesis of PC 23 1.36e-02 3.26e-02 0.44200 0.280000 3.42e-01 2.01e-02 4.52e-03
Plasma lipoprotein clearance 28 1.36e-02 3.27e-02 0.36900 0.184000 3.20e-01 9.23e-02 3.42e-03
RHO GTPases activate IQGAPs 11 1.38e-02 3.31e-02 0.60200 0.321000 5.09e-01 6.52e-02 3.43e-03
Membrane binding and targetting of GAG proteins 13 1.40e-02 3.34e-02 0.51700 0.231000 4.63e-01 1.50e-01 3.85e-03
Synthesis And Processing Of GAG, GAGPOL Polyproteins 13 1.40e-02 3.34e-02 0.51700 0.231000 4.63e-01 1.50e-01 3.85e-03
Nuclear import of Rev protein 34 1.41e-02 3.35e-02 0.29900 -0.109000 -2.78e-01 2.71e-01 4.97e-03
mRNA Splicing - Major Pathway 179 1.41e-02 3.35e-02 0.08440 -0.028900 7.93e-02 5.05e-01 6.71e-02
Export of Viral Ribonucleoproteins from Nucleus 33 1.43e-02 3.39e-02 0.27300 -0.064400 -2.65e-01 5.22e-01 8.40e-03
Base-Excision Repair, AP Site Formation 31 1.43e-02 3.39e-02 0.32700 0.137000 2.97e-01 1.87e-01 4.23e-03
Syndecan interactions 19 1.44e-02 3.41e-02 0.48200 0.375000 3.03e-01 4.68e-03 2.23e-02
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) 12 1.45e-02 3.43e-02 0.61500 0.416000 4.53e-01 1.26e-02 6.64e-03
Diseases of hemostasis 12 1.45e-02 3.43e-02 0.61500 0.416000 4.53e-01 1.26e-02 6.64e-03
Activation of GABAB receptors 31 1.46e-02 3.44e-02 0.38100 0.253000 2.85e-01 1.47e-02 6.03e-03
GABA B receptor activation 31 1.46e-02 3.44e-02 0.38100 0.253000 2.85e-01 1.47e-02 6.03e-03
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 11 1.48e-02 3.47e-02 0.57400 0.276000 5.04e-01 1.13e-01 3.83e-03
G beta:gamma signalling through PLC beta 17 1.49e-02 3.48e-02 0.50900 0.393000 3.24e-01 5.06e-03 2.07e-02
Presynaptic function of Kainate receptors 17 1.49e-02 3.48e-02 0.50900 0.393000 3.24e-01 5.06e-03 2.07e-02
Erythropoietin activates RAS 13 1.50e-02 3.50e-02 0.57800 0.360000 4.52e-01 2.45e-02 4.74e-03
DNA Damage/Telomere Stress Induced Senescence 44 1.50e-02 3.50e-02 0.26300 0.098000 2.44e-01 2.61e-01 5.16e-03
NS1 Mediated Effects on Host Pathways 40 1.52e-02 3.54e-02 0.30500 -0.153000 -2.64e-01 9.38e-02 3.85e-03
Phase 0 - rapid depolarisation 22 1.53e-02 3.56e-02 0.40000 -0.354000 -1.86e-01 4.07e-03 1.32e-01
SHC1 events in EGFR signaling 11 1.54e-02 3.56e-02 0.63800 0.432000 4.69e-01 1.30e-02 7.07e-03
RORA activates gene expression 18 1.54e-02 3.57e-02 0.39700 0.135000 3.74e-01 3.23e-01 6.01e-03
Integrin cell surface interactions 52 1.56e-02 3.61e-02 0.29300 0.217000 1.97e-01 6.86e-03 1.41e-02
Synthesis of Leukotrienes (LT) and Eoxins (EX) 15 1.58e-02 3.65e-02 0.33800 -0.000913 3.38e-01 9.95e-01 2.34e-02
Uptake and actions of bacterial toxins 27 1.61e-02 3.70e-02 0.39200 0.232000 3.16e-01 3.68e-02 4.49e-03
Signaling by ERBB4 44 1.61e-02 3.71e-02 0.31200 0.195000 2.44e-01 2.53e-02 5.15e-03
NOTCH3 Activation and Transmission of Signal to the Nucleus 23 1.62e-02 3.71e-02 0.33800 0.099800 3.23e-01 4.07e-01 7.41e-03
Response of EIF2AK1 (HRI) to heme deficiency 14 1.62e-02 3.72e-02 0.54100 0.439000 3.15e-01 4.41e-03 4.15e-02
Diseases associated with O-glycosylation of proteins 47 1.63e-02 3.72e-02 0.29600 -0.240000 -1.74e-01 4.49e-03 3.87e-02
MAP3K8 (TPL2)-dependent MAPK1/3 activation 16 1.66e-02 3.78e-02 0.44000 0.176000 4.03e-01 2.24e-01 5.24e-03
Purine ribonucleoside monophosphate biosynthesis 10 1.67e-02 3.81e-02 0.35100 0.113000 -3.32e-01 5.35e-01 6.88e-02
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 31 1.69e-02 3.84e-02 0.30200 -0.105000 -2.83e-01 3.10e-01 6.34e-03
Regulation of Glucokinase by Glucokinase Regulatory Protein 31 1.69e-02 3.84e-02 0.30200 -0.105000 -2.83e-01 3.10e-01 6.34e-03
Misspliced GSK3beta mutants stabilize beta-catenin 15 1.74e-02 3.92e-02 0.39000 0.086400 3.81e-01 5.62e-01 1.07e-02
S33 mutants of beta-catenin aren't phosphorylated 15 1.74e-02 3.92e-02 0.39000 0.086400 3.81e-01 5.62e-01 1.07e-02
S37 mutants of beta-catenin aren't phosphorylated 15 1.74e-02 3.92e-02 0.39000 0.086400 3.81e-01 5.62e-01 1.07e-02
S45 mutants of beta-catenin aren't phosphorylated 15 1.74e-02 3.92e-02 0.39000 0.086400 3.81e-01 5.62e-01 1.07e-02
T41 mutants of beta-catenin aren't phosphorylated 15 1.74e-02 3.92e-02 0.39000 0.086400 3.81e-01 5.62e-01 1.07e-02
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 15 1.74e-02 3.92e-02 0.39000 0.086400 3.81e-01 5.62e-01 1.07e-02
Regulation of IFNG signaling 14 1.74e-02 3.92e-02 0.50800 0.255000 4.39e-01 9.85e-02 4.47e-03
GTP hydrolysis and joining of the 60S ribosomal subunit 110 1.76e-02 3.94e-02 0.16400 -0.061900 -1.52e-01 2.62e-01 5.96e-03
G2/M Transition 178 1.77e-02 3.95e-02 0.11800 0.032600 1.14e-01 4.54e-01 8.75e-03
Glycogen breakdown (glycogenolysis) 13 1.78e-02 3.97e-02 0.52600 0.265000 4.54e-01 9.75e-02 4.56e-03
MET promotes cell motility 26 1.78e-02 3.98e-02 0.40900 0.286000 2.92e-01 1.15e-02 1.01e-02
B-WICH complex positively regulates rRNA expression 44 1.80e-02 4.01e-02 0.29300 0.247000 1.57e-01 4.61e-03 7.15e-02
Metabolism of amine-derived hormones 10 1.80e-02 4.01e-02 0.38000 0.046600 -3.78e-01 7.99e-01 3.87e-02
TRAF6 mediated NF-kB activation 23 1.83e-02 4.07e-02 0.37800 0.171000 3.37e-01 1.55e-01 5.08e-03
Sphingolipid de novo biosynthesis 42 1.86e-02 4.11e-02 0.31800 0.208000 2.40e-01 1.96e-02 7.17e-03
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 11 1.86e-02 4.11e-02 0.48500 0.149000 4.61e-01 3.92e-01 8.10e-03
G alpha (i) signalling events 243 1.93e-02 4.27e-02 0.12700 0.073800 1.04e-01 4.75e-02 5.28e-03
Peroxisomal protein import 57 1.96e-02 4.33e-02 0.25700 0.141000 2.14e-01 6.55e-02 5.11e-03
Interleukin-12 signaling 44 1.99e-02 4.36e-02 0.30900 0.208000 2.28e-01 1.68e-02 8.81e-03
Formation of the beta-catenin:TCF transactivating complex 46 1.99e-02 4.36e-02 0.27100 0.130000 2.38e-01 1.27e-01 5.30e-03
VxPx cargo-targeting to cilium 19 1.99e-02 4.36e-02 0.41000 0.184000 3.67e-01 1.66e-01 5.62e-03
Stimuli-sensing channels 72 1.99e-02 4.36e-02 0.24200 0.174000 1.68e-01 1.06e-02 1.35e-02
Retrograde transport at the Trans-Golgi-Network 49 1.99e-02 4.36e-02 0.26500 0.130000 2.31e-01 1.16e-01 5.24e-03
N-glycan antennae elongation in the medial/trans-Golgi 21 2.00e-02 4.37e-02 0.23800 -0.227000 7.33e-02 7.20e-02 5.61e-01
Prefoldin mediated transfer of substrate to CCT/TriC 26 2.03e-02 4.43e-02 0.39900 0.263000 3.00e-01 2.03e-02 8.02e-03
Negative regulation of FGFR1 signaling 24 2.05e-02 4.46e-02 0.37500 0.181000 3.28e-01 1.24e-01 5.43e-03
Negative regulation of FGFR3 signaling 20 2.05e-02 4.46e-02 0.41700 0.210000 3.60e-01 1.04e-01 5.34e-03
PKA activation in glucagon signalling 14 2.06e-02 4.47e-02 0.46000 0.186000 4.20e-01 2.28e-01 6.47e-03
ATF6 (ATF6-alpha) activates chaperones 12 2.07e-02 4.49e-02 0.58500 0.442000 3.85e-01 8.08e-03 2.11e-02
TP53 Regulates Transcription of DNA Repair Genes 61 2.11e-02 4.58e-02 0.14300 -0.139000 3.44e-02 6.11e-02 6.43e-01
mRNA Splicing 187 2.22e-02 4.79e-02 0.08050 -0.021200 7.77e-02 6.18e-01 6.69e-02
BMAL1:CLOCK,NPAS2 activates circadian gene expression 25 2.22e-02 4.79e-02 0.28500 0.052000 2.80e-01 6.53e-01 1.54e-02
HuR (ELAVL1) binds and stabilizes mRNA 10 2.24e-02 4.83e-02 0.61400 0.499000 3.57e-01 6.26e-03 5.08e-02
SUMOylation of intracellular receptors 25 2.26e-02 4.86e-02 0.29100 0.062300 2.84e-01 5.90e-01 1.39e-02
L13a-mediated translational silencing of Ceruloplasmin expression 109 2.28e-02 4.89e-02 0.16000 -0.060700 -1.48e-01 2.74e-01 7.77e-03
G beta:gamma signalling through PI3Kgamma 22 2.28e-02 4.89e-02 0.37100 0.162000 3.34e-01 1.90e-01 6.69e-03
Transport of bile salts and organic acids, metal ions and amine compounds 55 2.29e-02 4.89e-02 0.27100 0.183000 2.00e-01 1.87e-02 1.02e-02
ATF6 (ATF6-alpha) activates chaperone genes 10 2.29e-02 4.89e-02 0.63100 0.482000 4.06e-01 8.26e-03 2.62e-02
G beta:gamma signalling through BTK 15 2.31e-02 4.93e-02 0.50400 0.404000 3.01e-01 6.74e-03 4.38e-02
Butyrophilin (BTN) family interactions 10 2.38e-02 5.06e-02 0.63000 -0.475000 -4.13e-01 9.24e-03 2.37e-02
Signaling by EGFR in Cancer 22 2.42e-02 5.14e-02 0.42500 0.284000 3.17e-01 2.13e-02 1.02e-02
Ca-dependent events 29 2.42e-02 5.14e-02 0.31900 0.137000 2.88e-01 2.02e-01 7.23e-03
Interactions of Vpr with host cellular proteins 37 2.46e-02 5.21e-02 0.27300 -0.107000 -2.51e-01 2.59e-01 8.12e-03
Caspase activation via extrinsic apoptotic signalling pathway 25 2.50e-02 5.28e-02 0.39800 0.269000 2.93e-01 1.97e-02 1.13e-02
Metabolism of porphyrins 22 2.51e-02 5.30e-02 0.42200 0.278000 3.18e-01 2.41e-02 9.90e-03
Ion transport by P-type ATPases 43 2.54e-02 5.36e-02 0.14900 -0.117000 9.23e-02 1.85e-01 2.95e-01
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 79 2.56e-02 5.39e-02 0.21000 0.115000 1.76e-01 7.62e-02 6.85e-03
RNA polymerase II transcribes snRNA genes 72 2.60e-02 5.47e-02 0.19100 0.070900 1.78e-01 2.98e-01 9.17e-03
Nucleotide salvage 21 2.61e-02 5.49e-02 0.41800 0.249000 3.36e-01 4.86e-02 7.65e-03
TRAF6-mediated induction of TAK1 complex within TLR4 complex 16 2.63e-02 5.52e-02 0.48700 0.308000 3.78e-01 3.31e-02 8.92e-03
Formation of the Early Elongation Complex 33 2.70e-02 5.64e-02 0.20500 -0.012800 2.05e-01 8.99e-01 4.15e-02
Formation of the HIV-1 Early Elongation Complex 33 2.70e-02 5.64e-02 0.20500 -0.012800 2.05e-01 8.99e-01 4.15e-02
LDL clearance 17 2.71e-02 5.66e-02 0.47300 0.305000 3.61e-01 2.95e-02 9.86e-03
NGF-stimulated transcription 31 2.72e-02 5.67e-02 0.30700 0.135000 2.75e-01 1.93e-01 8.00e-03
Transport of Ribonucleoproteins into the Host Nucleus 32 2.76e-02 5.75e-02 0.27800 -0.095600 -2.61e-01 3.49e-01 1.06e-02
Removal of the Flap Intermediate 14 2.84e-02 5.91e-02 0.44300 -0.183000 -4.04e-01 2.35e-01 8.94e-03
Josephin domain DUBs 10 2.85e-02 5.91e-02 0.55100 0.262000 4.85e-01 1.51e-01 7.91e-03
Pyruvate metabolism 28 2.85e-02 5.91e-02 0.36700 0.278000 2.40e-01 1.10e-02 2.78e-02
Platelet calcium homeostasis 21 2.90e-02 6.00e-02 0.23900 -0.043600 2.35e-01 7.29e-01 6.19e-02
Mitotic Prophase 98 2.91e-02 6.01e-02 0.19600 0.129000 1.48e-01 2.76e-02 1.14e-02
Interferon gamma signaling 83 2.94e-02 6.07e-02 0.19100 -0.168000 -9.09e-02 8.20e-03 1.52e-01
NoRC negatively regulates rRNA expression 59 2.99e-02 6.15e-02 0.25200 0.169000 1.87e-01 2.48e-02 1.27e-02
Negative regulation of FGFR4 signaling 21 3.04e-02 6.25e-02 0.38600 0.195000 3.33e-01 1.22e-01 8.25e-03
Deadenylation of mRNA 22 3.06e-02 6.27e-02 0.34400 0.316000 1.34e-01 1.02e-02 2.75e-01
O-glycosylation of TSR domain-containing proteins 25 3.06e-02 6.28e-02 0.38500 -0.252000 -2.91e-01 2.94e-02 1.19e-02
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 36 3.09e-02 6.33e-02 0.18500 -0.026600 1.83e-01 7.82e-01 5.78e-02
Gastrin-CREB signalling pathway via PKC and MAPK 14 3.12e-02 6.37e-02 0.48500 0.265000 4.06e-01 8.56e-02 8.53e-03
FOXO-mediated transcription of cell death genes 16 3.12e-02 6.37e-02 0.43400 0.212000 3.79e-01 1.42e-01 8.63e-03
Signaling by FGFR1 in disease 30 3.14e-02 6.40e-02 0.33100 0.277000 1.81e-01 8.59e-03 8.64e-02
Separation of Sister Chromatids 167 3.15e-02 6.41e-02 0.13800 0.071600 1.18e-01 1.10e-01 8.55e-03
Polymerase switching on the C-strand of the telomere 26 3.15e-02 6.41e-02 0.37800 -0.259000 -2.76e-01 2.24e-02 1.50e-02
G alpha (q) signalling events 132 3.17e-02 6.44e-02 0.13000 0.039100 1.24e-01 4.38e-01 1.41e-02
Signaling by FGFR3 31 3.20e-02 6.47e-02 0.32700 0.182000 2.72e-01 8.01e-02 8.83e-03
Keratan sulfate biosynthesis 20 3.26e-02 6.60e-02 0.21700 -0.192000 1.01e-01 1.36e-01 4.36e-01
Regulation of signaling by CBL 18 3.28e-02 6.63e-02 0.38700 0.165000 3.50e-01 2.24e-01 1.01e-02
Common Pathway of Fibrin Clot Formation 14 3.29e-02 6.64e-02 0.49000 0.282000 4.01e-01 6.79e-02 9.40e-03
FOXO-mediated transcription 59 3.31e-02 6.67e-02 0.18900 0.053000 1.82e-01 4.82e-01 1.58e-02
AMER1 mutants destabilize the destruction complex 14 3.41e-02 6.80e-02 0.36000 0.067300 3.53e-01 6.63e-01 2.21e-02
APC truncation mutants have impaired AXIN binding 14 3.41e-02 6.80e-02 0.36000 0.067300 3.53e-01 6.63e-01 2.21e-02
AXIN missense mutants destabilize the destruction complex 14 3.41e-02 6.80e-02 0.36000 0.067300 3.53e-01 6.63e-01 2.21e-02
AXIN mutants destabilize the destruction complex, activating WNT signaling 14 3.41e-02 6.80e-02 0.36000 0.067300 3.53e-01 6.63e-01 2.21e-02
Truncations of AMER1 destabilize the destruction complex 14 3.41e-02 6.80e-02 0.36000 0.067300 3.53e-01 6.63e-01 2.21e-02
truncated APC mutants destabilize the destruction complex 14 3.41e-02 6.80e-02 0.36000 0.067300 3.53e-01 6.63e-01 2.21e-02
Signal regulatory protein family interactions 12 3.54e-02 7.05e-02 0.54400 0.360000 4.08e-01 3.08e-02 1.43e-02
Signaling by cytosolic FGFR1 fusion mutants 17 3.54e-02 7.05e-02 0.45600 0.347000 2.95e-01 1.33e-02 3.50e-02
Glycogen synthesis 13 3.61e-02 7.17e-02 0.48300 0.251000 4.13e-01 1.18e-01 9.95e-03
Collagen formation 64 3.66e-02 7.25e-02 0.20200 0.085700 1.83e-01 2.36e-01 1.14e-02
DAP12 interactions 39 3.69e-02 7.31e-02 0.25400 0.102000 2.32e-01 2.69e-01 1.21e-02
Frs2-mediated activation 11 3.70e-02 7.32e-02 0.52100 0.269000 4.47e-01 1.23e-01 1.03e-02
Activation of the AP-1 family of transcription factors 10 3.73e-02 7.36e-02 0.58600 0.454000 3.70e-01 1.29e-02 4.29e-02
RNA Polymerase I Promoter Escape 44 3.73e-02 7.36e-02 0.27500 0.221000 1.64e-01 1.14e-02 6.02e-02
Apoptotic factor-mediated response 18 3.74e-02 7.37e-02 0.44400 0.313000 3.14e-01 2.13e-02 2.11e-02
Interleukin-6 signaling 10 3.79e-02 7.45e-02 0.59200 0.437000 4.00e-01 1.68e-02 2.85e-02
Estrogen-dependent nuclear events downstream of ESR-membrane signaling 21 3.86e-02 7.57e-02 0.39400 0.232000 3.18e-01 6.52e-02 1.16e-02
Cap-dependent Translation Initiation 117 3.97e-02 7.77e-02 0.14400 -0.057100 -1.32e-01 2.86e-01 1.34e-02
Eukaryotic Translation Initiation 117 3.97e-02 7.77e-02 0.14400 -0.057100 -1.32e-01 2.86e-01 1.34e-02
Translation of Replicase and Assembly of the Replication Transcription Complex 12 3.98e-02 7.79e-02 0.53100 0.341000 4.07e-01 4.06e-02 1.46e-02
Regulation of localization of FOXO transcription factors 12 4.05e-02 7.92e-02 0.29400 -0.068800 2.86e-01 6.80e-01 8.63e-02
Class I peroxisomal membrane protein import 20 4.07e-02 7.94e-02 0.26400 -0.263000 -9.67e-03 4.14e-02 9.40e-01
Formation of tubulin folding intermediates by CCT/TriC 22 4.08e-02 7.95e-02 0.39400 0.264000 2.93e-01 3.24e-02 1.73e-02
Alpha-protein kinase 1 signaling pathway 11 4.15e-02 8.07e-02 0.55500 0.368000 4.16e-01 3.48e-02 1.70e-02
Nuclear Envelope (NE) Reassembly 69 4.22e-02 8.20e-02 0.17000 0.048500 1.63e-01 4.86e-01 1.96e-02
NOD1/2 Signaling Pathway 32 4.23e-02 8.21e-02 0.31700 0.192000 2.53e-01 5.97e-02 1.34e-02
Host Interactions of HIV factors 129 4.25e-02 8.24e-02 0.14600 0.071200 1.28e-01 1.63e-01 1.22e-02
DNA Damage Recognition in GG-NER 38 4.29e-02 8.29e-02 0.14600 -0.104000 1.02e-01 2.65e-01 2.77e-01
RIP-mediated NFkB activation via ZBP1 17 4.29e-02 8.29e-02 0.29400 0.027300 2.93e-01 8.46e-01 3.64e-02
FGFR1 mutant receptor activation 23 4.41e-02 8.50e-02 0.38100 0.281000 2.58e-01 1.96e-02 3.24e-02
RHO GTPases activate KTN1 11 4.42e-02 8.51e-02 0.55100 0.375000 4.05e-01 3.14e-02 2.01e-02
Signaling by FGFR4 31 4.50e-02 8.65e-02 0.32300 0.205000 2.50e-01 4.87e-02 1.58e-02
Cell junction organization 59 4.53e-02 8.69e-02 0.22900 0.186000 1.34e-01 1.37e-02 7.53e-02
Negative regulation of the PI3K/AKT network 86 4.67e-02 8.95e-02 0.16500 0.066700 1.51e-01 2.85e-01 1.56e-02
ZBP1(DAI) mediated induction of type I IFNs 20 4.72e-02 9.04e-02 0.27400 0.035000 2.72e-01 7.86e-01 3.55e-02
Keratan sulfate/keratin metabolism 25 4.73e-02 9.04e-02 0.21600 -0.015200 2.15e-01 8.95e-01 6.24e-02
Antigen Presentation: Folding, assembly and peptide loading of class I MHC 25 4.84e-02 9.23e-02 0.20500 -0.033400 2.02e-01 7.72e-01 8.04e-02
The role of Nef in HIV-1 replication and disease pathogenesis 28 4.94e-02 9.41e-02 0.30300 0.144000 2.67e-01 1.86e-01 1.46e-02
Cell-extracellular matrix interactions 14 4.95e-02 9.41e-02 0.46500 0.276000 3.74e-01 7.33e-02 1.54e-02
HDR through MMEJ (alt-NHEJ) 10 4.95e-02 9.41e-02 0.56700 -0.383000 -4.19e-01 3.62e-02 2.19e-02
Arachidonic acid metabolism 42 5.00e-02 9.49e-02 0.24100 0.106000 2.16e-01 2.33e-01 1.56e-02
Adenylate cyclase inhibitory pathway 11 5.03e-02 9.53e-02 0.33800 0.003620 3.38e-01 9.83e-01 5.23e-02
Orc1 removal from chromatin 69 5.13e-02 9.71e-02 0.19000 0.088000 1.69e-01 2.06e-01 1.55e-02
Formation of apoptosome 11 5.18e-02 9.78e-02 0.53400 0.351000 4.03e-01 4.39e-02 2.06e-02
Regulation of the apoptosome activity 11 5.18e-02 9.78e-02 0.53400 0.351000 4.03e-01 4.39e-02 2.06e-02
Cytosolic iron-sulfur cluster assembly 13 5.21e-02 9.83e-02 0.30700 -0.307000 3.92e-04 5.55e-02 9.98e-01
PKA activation 15 5.27e-02 9.92e-02 0.35600 0.108000 3.39e-01 4.67e-01 2.31e-02
Intraflagellar transport 39 5.51e-02 1.04e-01 0.27800 -0.173000 -2.17e-01 6.20e-02 1.89e-02
Intrinsic Pathway for Apoptosis 53 5.52e-02 1.04e-01 0.22900 0.127000 1.91e-01 1.10e-01 1.63e-02
NOTCH3 Intracellular Domain Regulates Transcription 20 5.56e-02 1.04e-01 0.30500 0.092800 2.91e-01 4.73e-01 2.44e-02
Meiotic synapsis 45 5.57e-02 1.04e-01 0.24700 0.135000 2.07e-01 1.18e-01 1.64e-02
Incretin synthesis, secretion, and inactivation 10 5.59e-02 1.04e-01 0.37500 0.372000 4.59e-02 4.16e-02 8.02e-01
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) 10 5.59e-02 1.04e-01 0.37500 0.372000 4.59e-02 4.16e-02 8.02e-01
Diseases associated with glycosylation precursor biosynthesis 18 5.59e-02 1.04e-01 0.39100 0.216000 3.26e-01 1.13e-01 1.65e-02
RMTs methylate histone arginines 37 5.60e-02 1.04e-01 0.14200 -0.088500 1.11e-01 3.51e-01 2.42e-01
Cell-Cell communication 88 5.62e-02 1.04e-01 0.18800 0.136000 1.30e-01 2.80e-02 3.47e-02
Metalloprotease DUBs 21 5.72e-02 1.06e-01 0.35100 0.179000 3.01e-01 1.56e-01 1.68e-02
AKT phosphorylates targets in the nucleus 10 5.73e-02 1.06e-01 0.30000 -0.289000 8.05e-02 1.14e-01 6.59e-01
Myogenesis 21 5.78e-02 1.07e-01 0.37200 0.224000 2.96e-01 7.52e-02 1.88e-02
Defective B3GALTL causes Peters-plus syndrome (PpS) 24 5.79e-02 1.07e-01 0.35400 -0.230000 -2.70e-01 5.15e-02 2.22e-02
Antiviral mechanism by IFN-stimulated genes 80 5.84e-02 1.08e-01 0.19400 -0.125000 -1.48e-01 5.24e-02 2.23e-02
DNA Repair 289 5.86e-02 1.08e-01 0.08700 -0.079500 -3.51e-02 2.00e-02 3.04e-01
G alpha (12/13) signalling events 68 5.92e-02 1.09e-01 0.20600 0.125000 1.64e-01 7.53e-02 1.94e-02
SLC-mediated transmembrane transport 178 5.93e-02 1.09e-01 0.12100 0.063100 1.03e-01 1.46e-01 1.74e-02
Inwardly rectifying K+ channels 24 5.94e-02 1.09e-01 0.32900 0.280000 1.73e-01 1.75e-02 1.42e-01
Cytochrome c-mediated apoptotic response 13 5.96e-02 1.09e-01 0.48300 0.333000 3.50e-01 3.78e-02 2.89e-02
Downregulation of TGF-beta receptor signaling 26 5.99e-02 1.10e-01 0.23000 0.028300 2.28e-01 8.03e-01 4.40e-02
Diseases of metabolism 185 6.08e-02 1.11e-01 0.07540 -0.006950 7.51e-02 8.71e-01 7.83e-02
Prostacyclin signalling through prostacyclin receptor 16 6.20e-02 1.13e-01 0.41800 0.337000 2.47e-01 1.97e-02 8.66e-02
Endogenous sterols 16 6.24e-02 1.14e-01 0.41800 0.250000 3.36e-01 8.36e-02 2.01e-02
Oncogene Induced Senescence 33 6.27e-02 1.14e-01 0.27300 0.136000 2.36e-01 1.76e-01 1.87e-02
Heme degradation 10 6.30e-02 1.15e-01 0.50600 0.267000 4.29e-01 1.43e-01 1.87e-02
Triglyceride catabolism 16 6.31e-02 1.15e-01 0.39100 0.195000 3.39e-01 1.77e-01 1.89e-02
Metabolism of steroid hormones 19 6.33e-02 1.15e-01 0.39200 0.256000 2.97e-01 5.37e-02 2.48e-02
Tight junction interactions 18 6.42e-02 1.16e-01 0.21300 0.200000 -7.29e-02 1.42e-01 5.92e-01
Laminin interactions 21 6.44e-02 1.17e-01 0.34100 0.295000 1.71e-01 1.93e-02 1.75e-01
Transcription of the HIV genome 67 6.53e-02 1.18e-01 0.14700 0.026400 1.45e-01 7.09e-01 4.06e-02
SRP-dependent cotranslational protein targeting to membrane 110 6.64e-02 1.20e-01 0.14800 -0.074000 -1.28e-01 1.80e-01 2.00e-02
Ion homeostasis 41 6.66e-02 1.20e-01 0.13300 -0.114000 6.90e-02 2.07e-01 4.45e-01
Leading Strand Synthesis 14 6.68e-02 1.20e-01 0.40400 -0.190000 -3.57e-01 2.19e-01 2.07e-02
Polymerase switching 14 6.68e-02 1.20e-01 0.40400 -0.190000 -3.57e-01 2.19e-01 2.07e-02
PINK1-PRKN Mediated Mitophagy 21 6.76e-02 1.21e-01 0.32500 0.290000 1.47e-01 2.15e-02 2.44e-01
Telomere C-strand synthesis initiation 13 6.78e-02 1.22e-01 0.47200 -0.343000 -3.24e-01 3.23e-02 4.30e-02
NF-kB is activated and signals survival 12 6.86e-02 1.23e-01 0.34000 0.055200 3.35e-01 7.41e-01 4.44e-02
Transcriptional Regulation by MECP2 47 6.91e-02 1.24e-01 0.17000 0.025200 1.68e-01 7.65e-01 4.65e-02
Apoptosis induced DNA fragmentation 10 7.03e-02 1.26e-01 0.48800 0.248000 4.21e-01 1.74e-01 2.13e-02
Activation of BAD and translocation to mitochondria 15 7.05e-02 1.26e-01 0.38500 0.179000 3.41e-01 2.31e-01 2.22e-02
Nuclear signaling by ERBB4 24 7.06e-02 1.26e-01 0.31600 0.162000 2.71e-01 1.70e-01 2.13e-02
Transport of Mature mRNA Derived from an Intronless Transcript 42 7.22e-02 1.28e-01 0.20700 -0.071000 -1.95e-01 4.26e-01 2.89e-02
Biotin transport and metabolism 11 7.30e-02 1.30e-01 0.50500 -0.370000 -3.44e-01 3.36e-02 4.81e-02
Cell death signalling via NRAGE, NRIF and NADE 69 7.34e-02 1.30e-01 0.16200 0.056900 1.52e-01 4.14e-01 2.88e-02
Nuclear Receptor transcription pathway 37 7.37e-02 1.31e-01 0.13900 -0.122000 6.62e-02 1.98e-01 4.86e-01
Formation of TC-NER Pre-Incision Complex 53 7.39e-02 1.31e-01 0.17200 0.045300 1.66e-01 5.69e-01 3.63e-02
tRNA Aminoacylation 42 7.52e-02 1.33e-01 0.20500 -0.069700 -1.93e-01 4.35e-01 3.04e-02
Olfactory Signaling Pathway 55 7.69e-02 1.36e-01 0.14100 0.141000 2.51e-03 7.11e-02 9.74e-01
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 17 7.76e-02 1.37e-01 0.40300 0.284000 2.86e-01 4.30e-02 4.14e-02
p75NTR signals via NF-kB 15 7.93e-02 1.40e-01 0.36600 0.158000 3.31e-01 2.91e-01 2.66e-02
Postmitotic nuclear pore complex (NPC) reformation 27 7.98e-02 1.40e-01 0.26200 -0.099900 -2.42e-01 3.69e-01 2.94e-02
Intrinsic Pathway of Fibrin Clot Formation 16 7.99e-02 1.40e-01 0.40700 0.313000 2.60e-01 3.00e-02 7.22e-02
Transport of vitamins, nucleosides, and related molecules 32 8.17e-02 1.43e-01 0.18200 0.003060 1.82e-01 9.76e-01 7.47e-02
Cell Cycle, Mitotic 500 8.35e-02 1.46e-01 0.04890 0.004740 4.87e-02 8.56e-01 6.26e-02
Late Phase of HIV Life Cycle 131 8.36e-02 1.46e-01 0.11800 0.044900 1.09e-01 3.75e-01 3.10e-02
Termination of translesion DNA synthesis 32 8.42e-02 1.47e-01 0.22400 -0.069200 -2.13e-01 4.98e-01 3.69e-02
Transport of Mature mRNAs Derived from Intronless Transcripts 43 8.56e-02 1.49e-01 0.18700 -0.050100 -1.80e-01 5.69e-01 4.14e-02
Interconversion of nucleotide di- and triphosphates 27 8.60e-02 1.50e-01 0.23000 0.223000 5.51e-02 4.48e-02 6.20e-01
HATs acetylate histones 93 8.61e-02 1.50e-01 0.08260 -0.053200 6.32e-02 3.75e-01 2.92e-01
Signaling by FGFR1 38 8.61e-02 1.50e-01 0.24300 0.126000 2.08e-01 1.77e-01 2.68e-02
Pyrimidine salvage 10 8.77e-02 1.52e-01 0.47200 0.247000 4.03e-01 1.77e-01 2.74e-02
Switching of origins to a post-replicative state 89 8.78e-02 1.52e-01 0.15500 0.075400 1.35e-01 2.19e-01 2.78e-02
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 18 8.84e-02 1.53e-01 0.34300 0.168000 2.99e-01 2.16e-01 2.80e-02
DNA Double Strand Break Response 47 8.94e-02 1.54e-01 0.14300 -0.004220 1.43e-01 9.60e-01 8.89e-02
CaM pathway 27 8.94e-02 1.54e-01 0.26100 0.106000 2.39e-01 3.40e-01 3.17e-02
Calmodulin induced events 27 8.94e-02 1.54e-01 0.26100 0.106000 2.39e-01 3.40e-01 3.17e-02
PRC2 methylates histones and DNA 29 8.95e-02 1.54e-01 0.29900 0.203000 2.19e-01 5.83e-02 4.10e-02
Glucose metabolism 83 9.07e-02 1.56e-01 0.16300 0.085600 1.39e-01 1.77e-01 2.84e-02
Negative epigenetic regulation of rRNA expression 62 9.10e-02 1.56e-01 0.20400 0.143000 1.46e-01 5.20e-02 4.65e-02
RET signaling 32 9.11e-02 1.56e-01 0.25300 0.121000 2.23e-01 2.37e-01 2.93e-02
SHC1 events in ERBB2 signaling 17 9.19e-02 1.57e-01 0.38600 0.292000 2.53e-01 3.74e-02 7.11e-02
EPHA-mediated growth cone collapse 13 9.24e-02 1.58e-01 0.37300 0.151000 3.41e-01 3.46e-01 3.30e-02
Chondroitin sulfate biosynthesis 12 9.26e-02 1.58e-01 0.39800 0.172000 3.58e-01 3.02e-01 3.16e-02
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 46 9.29e-02 1.59e-01 0.15200 0.009570 1.52e-01 9.11e-01 7.42e-02
Signaling by ERBB2 44 9.31e-02 1.59e-01 0.20700 0.088500 1.87e-01 3.10e-01 3.20e-02
Synthesis of substrates in N-glycan biosythesis 58 9.47e-02 1.61e-01 0.19800 0.111000 1.64e-01 1.42e-01 3.04e-02
RIPK1-mediated regulated necrosis 29 9.52e-02 1.62e-01 0.29300 0.191000 2.22e-01 7.52e-02 3.82e-02
Regulated Necrosis 29 9.52e-02 1.62e-01 0.29300 0.191000 2.22e-01 7.52e-02 3.82e-02
Regulation of necroptotic cell death 29 9.52e-02 1.62e-01 0.29300 0.191000 2.22e-01 7.52e-02 3.82e-02
Regulation of MECP2 expression and activity 28 9.67e-02 1.64e-01 0.19100 0.008330 1.91e-01 9.39e-01 8.01e-02
Metabolism of RNA 686 9.71e-02 1.64e-01 0.05790 -0.031900 -4.83e-02 1.54e-01 3.11e-02
TICAM1, RIP1-mediated IKK complex recruitment 19 9.71e-02 1.64e-01 0.32100 0.149000 2.84e-01 2.61e-01 3.19e-02
Ca2+ pathway 57 9.73e-02 1.64e-01 0.19800 0.165000 1.08e-01 3.11e-02 1.57e-01
Sialic acid metabolism 28 9.83e-02 1.66e-01 0.28900 0.172000 2.32e-01 1.16e-01 3.34e-02
Mitophagy 28 9.84e-02 1.66e-01 0.29000 0.231000 1.76e-01 3.42e-02 1.08e-01
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 26 9.85e-02 1.66e-01 0.29300 -0.163000 -2.43e-01 1.50e-01 3.17e-02
Carboxyterminal post-translational modifications of tubulin 26 9.98e-02 1.68e-01 0.23600 0.067600 2.26e-01 5.51e-01 4.63e-02
Surfactant metabolism 22 1.00e-01 1.68e-01 0.33600 0.240000 2.35e-01 5.18e-02 5.60e-02
Regulation of IFNA signaling 12 1.00e-01 1.68e-01 0.26600 -0.026200 2.65e-01 8.75e-01 1.12e-01
Elastic fibre formation 31 1.01e-01 1.69e-01 0.26400 0.142000 2.22e-01 1.72e-01 3.23e-02
TCR signaling 121 1.04e-01 1.75e-01 0.09820 0.015600 9.69e-02 7.67e-01 6.55e-02
Aggrephagy 21 1.06e-01 1.78e-01 0.32200 0.182000 2.66e-01 1.50e-01 3.49e-02
Pexophagy 11 1.07e-01 1.79e-01 0.42000 0.204000 3.67e-01 2.42e-01 3.50e-02
Nuclear Pore Complex (NPC) Disassembly 36 1.09e-01 1.81e-01 0.17400 -0.022000 -1.73e-01 8.19e-01 7.32e-02
Cytosolic sensors of pathogen-associated DNA 62 1.10e-01 1.82e-01 0.10300 -0.035400 9.67e-02 6.30e-01 1.88e-01
Keratinization 33 1.11e-01 1.84e-01 0.26800 0.196000 1.83e-01 5.18e-02 6.96e-02
Signaling by PDGFRA extracellular domain mutants 12 1.12e-01 1.86e-01 0.42200 0.347000 2.40e-01 3.73e-02 1.49e-01
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants 12 1.12e-01 1.86e-01 0.42200 0.347000 2.40e-01 3.73e-02 1.49e-01
NCAM1 interactions 23 1.12e-01 1.86e-01 0.23100 -0.050800 -2.26e-01 6.73e-01 6.10e-02
HIV Transcription Initiation 45 1.13e-01 1.86e-01 0.21500 0.117000 1.80e-01 1.73e-01 3.70e-02
RNA Polymerase II HIV Promoter Escape 45 1.13e-01 1.86e-01 0.21500 0.117000 1.80e-01 1.73e-01 3.70e-02
RNA Polymerase II Promoter Escape 45 1.13e-01 1.86e-01 0.21500 0.117000 1.80e-01 1.73e-01 3.70e-02
RNA Polymerase II Transcription Initiation 45 1.13e-01 1.86e-01 0.21500 0.117000 1.80e-01 1.73e-01 3.70e-02
RNA Polymerase II Transcription Initiation And Promoter Clearance 45 1.13e-01 1.86e-01 0.21500 0.117000 1.80e-01 1.73e-01 3.70e-02
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 45 1.13e-01 1.86e-01 0.21500 0.117000 1.80e-01 1.73e-01 3.70e-02
Glycogen storage diseases 13 1.13e-01 1.86e-01 0.38600 0.193000 3.34e-01 2.28e-01 3.71e-02
Caspase activation via Death Receptors in the presence of ligand 16 1.14e-01 1.86e-01 0.37400 0.295000 2.31e-01 4.13e-02 1.10e-01
Striated Muscle Contraction 24 1.14e-01 1.87e-01 0.28500 0.246000 1.45e-01 3.72e-02 2.18e-01
Signaling by FGFR in disease 50 1.15e-01 1.88e-01 0.21500 0.159000 1.45e-01 5.12e-02 7.63e-02
SUMOylation of RNA binding proteins 47 1.15e-01 1.88e-01 0.15600 -0.028000 -1.54e-01 7.40e-01 6.82e-02
Cilium Assembly 180 1.17e-01 1.91e-01 0.09780 -0.042300 -8.82e-02 3.28e-01 4.12e-02
Biological oxidations 132 1.18e-01 1.92e-01 0.13100 0.084300 1.00e-01 9.44e-02 4.67e-02
Disorders of Developmental Biology 12 1.19e-01 1.92e-01 0.28800 0.026100 2.87e-01 8.76e-01 8.55e-02
Disorders of Nervous System Development 12 1.19e-01 1.92e-01 0.28800 0.026100 2.87e-01 8.76e-01 8.55e-02
Loss of function of MECP2 in Rett syndrome 12 1.19e-01 1.92e-01 0.28800 0.026100 2.87e-01 8.76e-01 8.55e-02
Pervasive developmental disorders 12 1.19e-01 1.92e-01 0.28800 0.026100 2.87e-01 8.76e-01 8.55e-02
Acyl chain remodelling of PC 19 1.19e-01 1.93e-01 0.34700 0.236000 2.54e-01 7.53e-02 5.51e-02
HS-GAG biosynthesis 20 1.19e-01 1.93e-01 0.23400 0.037900 2.31e-01 7.69e-01 7.35e-02
CTLA4 inhibitory signaling 21 1.19e-01 1.93e-01 0.17700 -0.169000 5.21e-02 1.81e-01 6.79e-01
SUMOylation of transcription cofactors 44 1.20e-01 1.94e-01 0.13700 -0.008090 1.36e-01 9.26e-01 1.18e-01
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 19 1.22e-01 1.97e-01 0.16900 0.126000 -1.12e-01 3.40e-01 3.98e-01
Chaperone Mediated Autophagy 19 1.23e-01 1.97e-01 0.33500 0.267000 2.03e-01 4.38e-02 1.26e-01
Signaling by ERBB2 in Cancer 21 1.23e-01 1.97e-01 0.30600 0.258000 1.64e-01 4.06e-02 1.93e-01
MET activates RAS signaling 10 1.24e-01 1.99e-01 0.47100 0.355000 3.10e-01 5.19e-02 8.98e-02
Transcriptional Regulation by E2F6 34 1.25e-01 2.00e-01 0.19400 -0.052600 -1.86e-01 5.95e-01 6.01e-02
Translesion synthesis by REV1 16 1.28e-01 2.05e-01 0.36900 -0.242000 -2.78e-01 9.31e-02 5.38e-02
DDX58/IFIH1-mediated induction of interferon-alpha/beta 63 1.29e-01 2.06e-01 0.12500 0.014400 1.25e-01 8.43e-01 8.72e-02
Inositol phosphate metabolism 42 1.29e-01 2.07e-01 0.14300 0.001240 1.43e-01 9.89e-01 1.09e-01
Elevation of cytosolic Ca2+ levels 12 1.30e-01 2.08e-01 0.22500 -0.076600 2.11e-01 6.46e-01 2.05e-01
Interleukin-37 signaling 19 1.32e-01 2.10e-01 0.16600 -0.113000 1.21e-01 3.92e-01 3.62e-01
Scavenging by Class A Receptors 11 1.32e-01 2.10e-01 0.44400 0.299000 3.28e-01 8.60e-02 5.93e-02
GP1b-IX-V activation signalling 10 1.32e-01 2.10e-01 0.46200 0.297000 3.54e-01 1.04e-01 5.28e-02
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 18 1.32e-01 2.10e-01 0.34800 0.248000 2.44e-01 6.85e-02 7.32e-02
Signaling by Ligand-Responsive EGFR Variants in Cancer 18 1.32e-01 2.10e-01 0.34800 0.248000 2.44e-01 6.85e-02 7.32e-02
SUMOylation of DNA damage response and repair proteins 77 1.34e-01 2.13e-01 0.14200 -0.058200 -1.29e-01 3.78e-01 4.97e-02
Downregulation of ERBB2 signaling 24 1.36e-01 2.15e-01 0.24200 0.086500 2.26e-01 4.63e-01 5.52e-02
Regulation of TP53 Activity through Association with Co-factors 12 1.36e-01 2.16e-01 0.29400 -0.290000 -4.88e-02 8.24e-02 7.70e-01
GRB2 events in ERBB2 signaling 11 1.37e-01 2.16e-01 0.38700 0.344000 1.77e-01 4.79e-02 3.09e-01
Constitutive Signaling by EGFRvIII 14 1.37e-01 2.16e-01 0.38600 0.297000 2.46e-01 5.41e-02 1.12e-01
Signaling by EGFRvIII in Cancer 14 1.37e-01 2.16e-01 0.38600 0.297000 2.46e-01 5.41e-02 1.12e-01
MECP2 regulates neuronal receptors and channels 13 1.38e-01 2.18e-01 0.20100 -0.109000 1.69e-01 4.94e-01 2.93e-01
RAS processing 19 1.38e-01 2.18e-01 0.21600 0.013300 2.16e-01 9.20e-01 1.04e-01
RNA Pol II CTD phosphorylation and interaction with CE 27 1.39e-01 2.18e-01 0.20700 0.051200 2.01e-01 6.45e-01 7.07e-02
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 27 1.39e-01 2.18e-01 0.20700 0.051200 2.01e-01 6.45e-01 7.07e-02
SHC1 events in ERBB4 signaling 10 1.39e-01 2.19e-01 0.44000 0.360000 2.53e-01 4.85e-02 1.66e-01
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein 73 1.41e-01 2.21e-01 0.17000 0.123000 1.17e-01 6.86e-02 8.37e-02
Insulin receptor signalling cascade 39 1.42e-01 2.22e-01 0.23200 0.164000 1.65e-01 7.64e-02 7.52e-02
Activation of kainate receptors upon glutamate binding 25 1.43e-01 2.23e-01 0.28700 0.217000 1.89e-01 6.03e-02 1.03e-01
Association of TriC/CCT with target proteins during biosynthesis 37 1.45e-01 2.27e-01 0.14300 -0.006980 1.43e-01 9.41e-01 1.33e-01
SUMOylation of SUMOylation proteins 35 1.46e-01 2.28e-01 0.18700 -0.055700 -1.79e-01 5.68e-01 6.73e-02
Glycolysis 66 1.46e-01 2.28e-01 0.17600 0.132000 1.16e-01 6.30e-02 1.02e-01
Peroxisomal lipid metabolism 27 1.47e-01 2.28e-01 0.27700 0.199000 1.93e-01 7.41e-02 8.33e-02
Signaling by PDGF 44 1.47e-01 2.28e-01 0.21400 0.165000 1.36e-01 5.86e-02 1.18e-01
Diseases associated with glycosaminoglycan metabolism 25 1.47e-01 2.29e-01 0.15800 -0.035200 1.54e-01 7.60e-01 1.82e-01
Attenuation phase 23 1.48e-01 2.29e-01 0.29500 0.189000 2.27e-01 1.17e-01 5.93e-02
Defects in vitamin and cofactor metabolism 21 1.48e-01 2.29e-01 0.28500 -0.144000 -2.46e-01 2.52e-01 5.08e-02
Cholesterol biosynthesis 24 1.49e-01 2.31e-01 0.16600 -0.027300 1.63e-01 8.17e-01 1.66e-01
PERK regulates gene expression 31 1.50e-01 2.32e-01 0.17300 0.172000 2.17e-02 9.79e-02 8.35e-01
Metabolism of fat-soluble vitamins 28 1.51e-01 2.33e-01 0.23400 0.103000 2.10e-01 3.46e-01 5.47e-02
HIV Life Cycle 144 1.52e-01 2.34e-01 0.10000 0.040600 9.16e-02 4.01e-01 5.78e-02
Apoptotic cleavage of cellular proteins 34 1.52e-01 2.34e-01 0.22900 0.125000 1.92e-01 2.08e-01 5.25e-02
Synthesis of very long-chain fatty acyl-CoAs 21 1.53e-01 2.35e-01 0.30900 0.230000 2.07e-01 6.86e-02 1.00e-01
Mitochondrial iron-sulfur cluster biogenesis 13 1.58e-01 2.42e-01 0.38800 0.293000 2.55e-01 6.75e-02 1.11e-01
Potassium Channels 63 1.58e-01 2.42e-01 0.17600 0.135000 1.13e-01 6.41e-02 1.22e-01
Listeria monocytogenes entry into host cells 17 1.59e-01 2.43e-01 0.31000 0.156000 2.68e-01 2.66e-01 5.53e-02
Nucleotide Excision Repair 110 1.59e-01 2.43e-01 0.06660 -0.037200 5.53e-02 5.01e-01 3.17e-01
Retinoid metabolism and transport 24 1.62e-01 2.47e-01 0.23400 0.087800 2.17e-01 4.57e-01 6.53e-02
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol 16 1.62e-01 2.48e-01 0.34600 0.223000 2.65e-01 1.22e-01 6.69e-02
PI3K events in ERBB2 signaling 11 1.63e-01 2.48e-01 0.37200 0.330000 1.72e-01 5.84e-02 3.22e-01
Signaling by Hippo 18 1.66e-01 2.53e-01 0.32600 0.217000 2.44e-01 1.11e-01 7.32e-02
Collagen biosynthesis and modifying enzymes 46 1.68e-01 2.55e-01 0.13700 0.015100 1.36e-01 8.60e-01 1.11e-01
Translesion synthesis by POLI 17 1.69e-01 2.57e-01 0.32300 -0.190000 -2.62e-01 1.75e-01 6.19e-02
TP53 Regulates Transcription of Cell Death Genes 43 1.70e-01 2.59e-01 0.20000 0.165000 1.13e-01 6.09e-02 1.98e-01
mRNA Splicing - Minor Pathway 52 1.71e-01 2.59e-01 0.11500 -0.005920 1.15e-01 9.41e-01 1.51e-01
Diseases of glycosylation 106 1.72e-01 2.60e-01 0.07020 -0.065800 2.46e-02 2.42e-01 6.61e-01
Trafficking and processing of endosomal TLR 13 1.72e-01 2.61e-01 0.38100 0.256000 2.81e-01 1.10e-01 7.90e-02
Deactivation of the beta-catenin transactivating complex 36 1.74e-01 2.63e-01 0.11300 -0.064900 9.25e-02 5.00e-01 3.37e-01
RA biosynthesis pathway 13 1.75e-01 2.64e-01 0.34200 -0.298000 -1.66e-01 6.26e-02 2.99e-01
EGR2 and SOX10-mediated initiation of Schwann cell myelination 22 1.75e-01 2.64e-01 0.14300 -0.095100 1.06e-01 4.40e-01 3.87e-01
Folding of actin by CCT/TriC 10 1.76e-01 2.66e-01 0.35800 0.330000 1.38e-01 7.07e-02 4.51e-01
Cardiac conduction 86 1.77e-01 2.66e-01 0.07370 -0.063200 3.79e-02 3.11e-01 5.43e-01
Signaling by FGFR4 in disease 11 1.77e-01 2.66e-01 0.25200 0.252000 -5.66e-03 1.48e-01 9.74e-01
Interleukin-6 family signaling 18 1.79e-01 2.69e-01 0.30700 0.251000 1.77e-01 6.55e-02 1.93e-01
VEGFR2 mediated vascular permeability 26 1.80e-01 2.70e-01 0.14100 -0.046300 1.33e-01 6.83e-01 2.41e-01
Transport of Mature mRNA derived from an Intron-Containing Transcript 72 1.81e-01 2.72e-01 0.12600 -0.041800 -1.19e-01 5.40e-01 7.99e-02
Signaling by FGFR 69 1.81e-01 2.72e-01 0.12100 0.029600 1.17e-01 6.70e-01 9.31e-02
Mitochondrial tRNA aminoacylation 21 1.82e-01 2.72e-01 0.29300 -0.189000 -2.23e-01 1.33e-01 7.66e-02
Negative regulation of FGFR2 signaling 23 1.82e-01 2.72e-01 0.25500 0.125000 2.22e-01 2.98e-01 6.55e-02
Interleukin-15 signaling 14 1.82e-01 2.72e-01 0.36200 0.249000 2.62e-01 1.07e-01 8.95e-02
Synthesis of IP3 and IP4 in the cytosol 22 1.83e-01 2.72e-01 0.15600 -0.040900 1.51e-01 7.40e-01 2.20e-01
FRS-mediated FGFR3 signaling 11 1.84e-01 2.74e-01 0.33600 0.311000 1.29e-01 7.45e-02 4.59e-01
O-linked glycosylation of mucins 46 1.86e-01 2.77e-01 0.17900 0.088400 1.56e-01 3.00e-01 6.73e-02
Signaling by FGFR3 in disease 13 1.86e-01 2.77e-01 0.19800 0.189000 -6.14e-02 2.39e-01 7.02e-01
Signaling by FGFR3 point mutants in cancer 13 1.86e-01 2.77e-01 0.19800 0.189000 -6.14e-02 2.39e-01 7.02e-01
Cytosolic tRNA aminoacylation 24 1.88e-01 2.78e-01 0.13700 0.071900 -1.16e-01 5.42e-01 3.25e-01
Receptor Mediated Mitophagy 11 1.89e-01 2.79e-01 0.39700 0.250000 3.09e-01 1.50e-01 7.63e-02
Plasma lipoprotein remodeling 18 1.89e-01 2.79e-01 0.25200 0.086800 2.37e-01 5.24e-01 8.17e-02
Processive synthesis on the C-strand of the telomere 19 1.89e-01 2.80e-01 0.30400 -0.198000 -2.31e-01 1.36e-01 8.09e-02
Assembly and cell surface presentation of NMDA receptors 18 1.93e-01 2.86e-01 0.17600 0.031900 -1.73e-01 8.15e-01 2.03e-01
Biosynthesis of specialized proresolving mediators (SPMs) 16 1.95e-01 2.87e-01 0.32400 0.198000 2.56e-01 1.69e-01 7.61e-02
Downstream signal transduction 27 1.96e-01 2.89e-01 0.25400 0.168000 1.90e-01 1.31e-01 8.73e-02
ISG15 antiviral mechanism 72 1.97e-01 2.90e-01 0.15100 -0.089200 -1.22e-01 1.91e-01 7.45e-02
SUMOylation of chromatin organization proteins 57 1.98e-01 2.90e-01 0.11700 -0.013100 -1.16e-01 8.64e-01 1.29e-01
Resolution of D-Loop Structures 33 1.98e-01 2.91e-01 0.23000 -0.161000 -1.64e-01 1.09e-01 1.03e-01
PI3K/AKT Signaling in Cancer 80 1.98e-01 2.91e-01 0.12800 0.056500 1.15e-01 3.82e-01 7.56e-02
Signaling by ERBB2 KD Mutants 20 1.99e-01 2.91e-01 0.26300 0.231000 1.26e-01 7.33e-02 3.29e-01
Gap-filling DNA repair synthesis and ligation in GG-NER 25 2.00e-01 2.92e-01 0.25900 -0.163000 -2.01e-01 1.58e-01 8.15e-02
Mitotic Telophase/Cytokinesis 13 2.00e-01 2.92e-01 0.36100 0.233000 2.76e-01 1.46e-01 8.47e-02
Tie2 Signaling 16 2.00e-01 2.92e-01 0.32400 0.205000 2.51e-01 1.56e-01 8.19e-02
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 12 2.00e-01 2.92e-01 0.38000 0.277000 2.59e-01 9.65e-02 1.20e-01
Acyl chain remodelling of PI 10 2.00e-01 2.92e-01 0.41500 0.307000 2.79e-01 9.28e-02 1.26e-01
Rap1 signalling 13 2.02e-01 2.94e-01 0.35200 0.209000 2.83e-01 1.91e-01 7.71e-02
Depolymerisation of the Nuclear Lamina 15 2.03e-01 2.95e-01 0.30000 0.142000 2.65e-01 3.42e-01 7.57e-02
Downstream TCR signaling 100 2.04e-01 2.96e-01 0.10300 0.033400 9.76e-02 5.64e-01 9.18e-02
RNA Polymerase I Transcription Initiation 44 2.04e-01 2.96e-01 0.19600 -0.131000 -1.47e-01 1.34e-01 9.20e-02
DAG and IP3 signaling 33 2.06e-01 2.99e-01 0.17100 0.046300 1.65e-01 6.45e-01 1.02e-01
Beta-oxidation of very long chain fatty acids 10 2.06e-01 2.99e-01 0.39000 0.218000 3.24e-01 2.33e-01 7.64e-02
RNA Polymerase I Transcription Termination 27 2.07e-01 2.99e-01 0.13200 0.043400 -1.25e-01 6.97e-01 2.61e-01
Resolution of D-loop Structures through Holliday Junction Intermediates 32 2.07e-01 3.00e-01 0.22600 -0.142000 -1.76e-01 1.63e-01 8.51e-02
CD28 dependent Vav1 pathway 12 2.08e-01 3.00e-01 0.31800 0.289000 1.31e-01 8.25e-02 4.33e-01
Nitric oxide stimulates guanylate cyclase 14 2.08e-01 3.00e-01 0.30700 0.272000 1.44e-01 7.82e-02 3.52e-01
Formation of Senescence-Associated Heterochromatin Foci (SAHF) 13 2.08e-01 3.00e-01 0.23900 0.023700 2.38e-01 8.82e-01 1.38e-01
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 14 2.09e-01 3.00e-01 0.31200 -0.152000 -2.72e-01 3.26e-01 7.75e-02
Chondroitin sulfate/dermatan sulfate metabolism 38 2.10e-01 3.01e-01 0.13300 0.004400 1.33e-01 9.63e-01 1.55e-01
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 21 2.11e-01 3.03e-01 0.24200 0.104000 2.19e-01 4.12e-01 8.25e-02
Diseases of DNA repair 10 2.12e-01 3.04e-01 0.40600 -0.305000 -2.67e-01 9.44e-02 1.44e-01
SUMOylation of ubiquitinylation proteins 39 2.12e-01 3.04e-01 0.14900 -0.031500 -1.45e-01 7.33e-01 1.16e-01
Triglyceride metabolism 25 2.14e-01 3.07e-01 0.24200 0.132000 2.03e-01 2.52e-01 7.96e-02
Positive epigenetic regulation of rRNA expression 59 2.18e-01 3.12e-01 0.16700 0.118000 1.18e-01 1.17e-01 1.16e-01
ERBB2 Regulates Cell Motility 10 2.19e-01 3.13e-01 0.40400 0.278000 2.93e-01 1.28e-01 1.08e-01
PKA-mediated phosphorylation of CREB 17 2.20e-01 3.14e-01 0.25600 0.098200 2.36e-01 4.83e-01 9.17e-02
Acyl chain remodelling of PE 20 2.22e-01 3.16e-01 0.27300 0.223000 1.58e-01 8.47e-02 2.22e-01
Regulation of TP53 Expression and Degradation 36 2.23e-01 3.17e-01 0.10700 -0.094000 5.09e-02 3.29e-01 5.97e-01
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 59 2.23e-01 3.17e-01 0.08660 0.080900 -3.09e-02 2.82e-01 6.82e-01
FRS-mediated FGFR4 signaling 12 2.23e-01 3.17e-01 0.29300 0.275000 1.01e-01 9.85e-02 5.43e-01
Signaling by NTRK2 (TRKB) 20 2.25e-01 3.19e-01 0.25800 0.223000 1.31e-01 8.42e-02 3.12e-01
p38MAPK events 13 2.27e-01 3.22e-01 0.31800 0.160000 2.76e-01 3.19e-01 8.54e-02
NOTCH4 Intracellular Domain Regulates Transcription 17 2.27e-01 3.22e-01 0.16400 -0.048900 1.56e-01 7.27e-01 2.65e-01
TP53 Regulates Transcription of Cell Cycle Genes 47 2.28e-01 3.22e-01 0.13200 0.129000 2.80e-02 1.25e-01 7.40e-01
Signalling to RAS 18 2.29e-01 3.23e-01 0.29700 0.211000 2.10e-01 1.22e-01 1.24e-01
RNA Polymerase III Transcription Initiation From Type 1 Promoter 28 2.30e-01 3.25e-01 0.23000 -0.185000 -1.38e-01 9.09e-02 2.07e-01
Ovarian tumor domain proteases 37 2.30e-01 3.25e-01 0.12700 -0.001650 1.27e-01 9.86e-01 1.80e-01
Translation initiation complex formation 58 2.31e-01 3.25e-01 0.08250 0.070800 -4.24e-02 3.51e-01 5.76e-01
Heme biosynthesis 14 2.31e-01 3.25e-01 0.33600 0.241000 2.33e-01 1.18e-01 1.31e-01
Bile acid and bile salt metabolism 28 2.31e-01 3.25e-01 0.19400 0.071200 1.80e-01 5.14e-01 9.93e-02
Translesion synthesis by POLK 17 2.32e-01 3.26e-01 0.29500 -0.177000 -2.36e-01 2.07e-01 9.19e-02
IRAK2 mediated activation of TAK1 complex 10 2.36e-01 3.31e-01 0.33600 0.141000 3.05e-01 4.39e-01 9.51e-02
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12 2.36e-01 3.31e-01 0.18000 -0.092100 1.55e-01 5.81e-01 3.54e-01
Constitutive Signaling by NOTCH1 HD Domain Mutants 14 2.37e-01 3.32e-01 0.16300 -0.124000 1.05e-01 4.21e-01 4.96e-01
Signaling by NOTCH1 HD Domain Mutants in Cancer 14 2.37e-01 3.32e-01 0.16300 -0.124000 1.05e-01 4.21e-01 4.96e-01
NOTCH2 Activation and Transmission of Signal to the Nucleus 20 2.39e-01 3.34e-01 0.18400 0.018600 1.83e-01 8.86e-01 1.56e-01
Chemokine receptors bind chemokines 39 2.43e-01 3.39e-01 0.18900 -0.109000 -1.55e-01 2.39e-01 9.47e-02
Transcriptional regulation by small RNAs 63 2.44e-01 3.40e-01 0.15500 0.104000 1.15e-01 1.55e-01 1.14e-01
DNA Double-Strand Break Repair 135 2.44e-01 3.40e-01 0.10500 -0.080500 -6.78e-02 1.06e-01 1.74e-01
RNA Polymerase III Transcription Initiation From Type 2 Promoter 27 2.44e-01 3.40e-01 0.22400 -0.186000 -1.25e-01 9.38e-02 2.60e-01
Phase I - Functionalization of compounds 61 2.44e-01 3.40e-01 0.15700 0.104000 1.18e-01 1.61e-01 1.11e-01
Cell-cell junction organization 38 2.47e-01 3.43e-01 0.13100 0.130000 1.14e-02 1.65e-01 9.03e-01
Formation of the ternary complex, and subsequently, the 43S complex 51 2.48e-01 3.45e-01 0.10200 0.008230 -1.01e-01 9.19e-01 2.11e-01
RUNX2 regulates osteoblast differentiation 17 2.49e-01 3.45e-01 0.15700 -0.149000 5.07e-02 2.89e-01 7.18e-01
DAP12 signaling 28 2.51e-01 3.47e-01 0.11500 -0.060600 9.76e-02 5.79e-01 3.71e-01
Glutamate binding, activation of AMPA receptors and synaptic plasticity 20 2.51e-01 3.47e-01 0.19200 0.035200 1.89e-01 7.85e-01 1.44e-01
Trafficking of AMPA receptors 20 2.51e-01 3.47e-01 0.19200 0.035200 1.89e-01 7.85e-01 1.44e-01
p75NTR recruits signalling complexes 12 2.52e-01 3.48e-01 0.29900 0.126000 2.72e-01 4.51e-01 1.03e-01
RUNX2 regulates bone development 22 2.53e-01 3.50e-01 0.13700 -0.044500 1.30e-01 7.18e-01 2.93e-01
TNFR1-induced proapoptotic signaling 12 2.55e-01 3.51e-01 0.35000 -0.256000 -2.38e-01 1.24e-01 1.54e-01
CD209 (DC-SIGN) signaling 20 2.56e-01 3.52e-01 0.26000 0.152000 2.12e-01 2.40e-01 1.01e-01
HSF1-dependent transactivation 29 2.57e-01 3.53e-01 0.18800 0.075500 1.73e-01 4.82e-01 1.08e-01
Cell Cycle 622 2.60e-01 3.58e-01 0.02430 -0.013300 2.03e-02 5.71e-01 3.87e-01
Fatty acyl-CoA biosynthesis 33 2.62e-01 3.60e-01 0.20300 0.121000 1.62e-01 2.28e-01 1.06e-01
Meiotic recombination 38 2.63e-01 3.61e-01 0.19100 0.149000 1.19e-01 1.12e-01 2.03e-01
MASTL Facilitates Mitotic Progression 10 2.63e-01 3.61e-01 0.37900 0.271000 2.65e-01 1.38e-01 1.47e-01
Metabolic disorders of biological oxidation enzymes 23 2.68e-01 3.66e-01 0.20300 0.075400 1.89e-01 5.31e-01 1.17e-01
Plasma lipoprotein assembly 10 2.69e-01 3.67e-01 0.27800 0.069400 2.70e-01 7.04e-01 1.40e-01
Other interleukin signaling 18 2.70e-01 3.68e-01 0.15900 -0.024800 1.57e-01 8.56e-01 2.47e-01
Signaling by FGFR2 IIIa TM 18 2.70e-01 3.68e-01 0.20200 0.044300 1.97e-01 7.45e-01 1.47e-01
Dual Incision in GG-NER 41 2.72e-01 3.71e-01 0.16700 -0.082500 -1.45e-01 3.61e-01 1.07e-01
NRIF signals cell death from the nucleus 15 2.76e-01 3.76e-01 0.27000 0.128000 2.38e-01 3.90e-01 1.10e-01
Cargo trafficking to the periciliary membrane 47 2.77e-01 3.76e-01 0.12600 0.122000 2.96e-02 1.47e-01 7.25e-01
Regulation of HSF1-mediated heat shock response 79 2.79e-01 3.79e-01 0.06660 0.031500 -5.87e-02 6.28e-01 3.67e-01
Signaling by FGFR2 60 2.79e-01 3.79e-01 0.13800 0.068900 1.19e-01 3.56e-01 1.11e-01
TICAM1,TRAF6-dependent induction of TAK1 complex 11 2.81e-01 3.82e-01 0.34000 0.200000 2.74e-01 2.50e-01 1.15e-01
Regulation of TP53 Degradation 35 2.82e-01 3.82e-01 0.09650 -0.072000 6.43e-02 4.61e-01 5.10e-01
Peptide ligand-binding receptors 95 2.83e-01 3.83e-01 0.12000 0.086300 8.32e-02 1.46e-01 1.61e-01
Downstream signaling of activated FGFR3 16 2.84e-01 3.83e-01 0.23100 0.218000 7.76e-02 1.31e-01 5.91e-01
Ribosomal scanning and start codon recognition 58 2.84e-01 3.83e-01 0.07550 0.061400 -4.40e-02 4.19e-01 5.63e-01
Processing of Capped Intron-Containing Pre-mRNA 238 2.85e-01 3.84e-01 0.03740 -0.021600 3.05e-02 5.65e-01 4.18e-01
Carnitine metabolism 10 2.85e-01 3.84e-01 0.35200 0.204000 2.87e-01 2.65e-01 1.16e-01
RUNX3 regulates NOTCH signaling 14 2.87e-01 3.86e-01 0.24300 0.077700 2.30e-01 6.15e-01 1.36e-01
Interleukin-27 signaling 11 2.87e-01 3.86e-01 0.34400 0.216000 2.68e-01 2.15e-01 1.24e-01
Degradation of cysteine and homocysteine 12 2.89e-01 3.88e-01 0.21800 0.016700 2.17e-01 9.20e-01 1.93e-01
Synthesis of PIPs at the late endosome membrane 11 2.89e-01 3.88e-01 0.33400 0.272000 1.93e-01 1.18e-01 2.67e-01
Signaling by ERBB2 TMD/JMD mutants 17 2.89e-01 3.88e-01 0.25900 0.221000 1.36e-01 1.15e-01 3.30e-01
Glutathione conjugation 26 2.90e-01 3.88e-01 0.22600 0.153000 1.67e-01 1.78e-01 1.42e-01
Ephrin signaling 17 2.93e-01 3.93e-01 0.27200 0.167000 2.15e-01 2.34e-01 1.25e-01
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 11 2.97e-01 3.97e-01 0.17000 0.139000 -9.84e-02 4.25e-01 5.72e-01
Phase II - Conjugation of compounds 66 3.00e-01 4.01e-01 0.13700 0.085400 1.08e-01 2.30e-01 1.30e-01
Transcriptional activation of mitochondrial biogenesis 51 3.02e-01 4.04e-01 0.15300 0.088700 1.24e-01 2.73e-01 1.25e-01
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 43 3.03e-01 4.04e-01 0.12100 0.022000 1.19e-01 8.03e-01 1.75e-01
CD28 co-stimulation 33 3.03e-01 4.04e-01 0.12000 -0.120000 3.64e-03 2.32e-01 9.71e-01
Adrenaline,noradrenaline inhibits insulin secretion 24 3.04e-01 4.04e-01 0.22800 0.176000 1.45e-01 1.36e-01 2.18e-01
Signaling by NOTCH2 30 3.05e-01 4.06e-01 0.16600 0.058900 1.56e-01 5.77e-01 1.40e-01
mRNA decay by 3' to 5' exoribonuclease 16 3.07e-01 4.07e-01 0.23500 -0.092300 -2.16e-01 5.23e-01 1.35e-01
Metabolism of folate and pterines 16 3.08e-01 4.09e-01 0.26100 0.222000 1.37e-01 1.25e-01 3.43e-01
Tryptophan catabolism 12 3.09e-01 4.09e-01 0.30700 0.255000 1.71e-01 1.26e-01 3.04e-01
Cytosolic sulfonation of small molecules 18 3.11e-01 4.11e-01 0.18500 0.031900 1.82e-01 8.15e-01 1.82e-01
Downstream signaling of activated FGFR4 17 3.14e-01 4.16e-01 0.20800 0.198000 6.10e-02 1.57e-01 6.63e-01
Telomere Extension By Telomerase 23 3.16e-01 4.17e-01 0.16900 -0.165000 -3.87e-02 1.71e-01 7.48e-01
Metabolism of cofactors 19 3.20e-01 4.22e-01 0.23600 0.125000 2.00e-01 3.46e-01 1.31e-01
FRS-mediated FGFR2 signaling 14 3.20e-01 4.23e-01 0.15800 0.150000 -4.80e-02 3.31e-01 7.56e-01
Assembly of collagen fibrils and other multimeric structures 42 3.21e-01 4.23e-01 0.16900 0.110000 1.29e-01 2.17e-01 1.49e-01
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 17 3.23e-01 4.26e-01 0.17200 -0.010100 -1.72e-01 9.43e-01 2.20e-01
RNA Polymerase I Promoter Clearance 63 3.24e-01 4.26e-01 0.13600 0.085200 1.07e-01 2.42e-01 1.44e-01
RNA Polymerase I Transcription 63 3.24e-01 4.26e-01 0.13600 0.085200 1.07e-01 2.42e-01 1.44e-01
Metabolism of vitamins and cofactors 156 3.28e-01 4.30e-01 0.06980 0.023300 6.58e-02 6.16e-01 1.56e-01
Chromosome Maintenance 105 3.28e-01 4.30e-01 0.10700 -0.071500 -7.93e-02 2.06e-01 1.60e-01
G2/M Checkpoints 138 3.34e-01 4.37e-01 0.08550 0.044400 7.31e-02 3.68e-01 1.38e-01
Constitutive Signaling by Overexpressed ERBB2 11 3.40e-01 4.45e-01 0.32200 0.208000 2.45e-01 2.32e-01 1.59e-01
Assembly of active LPL and LIPC lipase complexes 10 3.41e-01 4.45e-01 0.27200 0.092800 2.55e-01 6.11e-01 1.62e-01
Mitochondrial calcium ion transport 22 3.42e-01 4.46e-01 0.21700 0.180000 1.21e-01 1.44e-01 3.25e-01
VEGFR2 mediated cell proliferation 18 3.42e-01 4.46e-01 0.24500 0.145000 1.97e-01 2.86e-01 1.47e-01
Recognition of DNA damage by PCNA-containing replication complex 30 3.45e-01 4.49e-01 0.17300 -0.080600 -1.53e-01 4.45e-01 1.47e-01
Defects in cobalamin (B12) metabolism 13 3.49e-01 4.55e-01 0.19800 -0.024000 -1.97e-01 8.81e-01 2.19e-01
RAF-independent MAPK1/3 activation 21 3.50e-01 4.55e-01 0.19700 0.081700 1.79e-01 5.17e-01 1.55e-01
Metabolism of nitric oxide: NOS3 activation and regulation 12 3.53e-01 4.59e-01 0.28900 0.160000 2.40e-01 3.37e-01 1.50e-01
ATF4 activates genes in response to endoplasmic reticulum stress 26 3.56e-01 4.63e-01 0.11200 0.107000 -3.04e-02 3.43e-01 7.88e-01
Removal of the Flap Intermediate from the C-strand 17 3.57e-01 4.63e-01 0.25500 -0.177000 -1.84e-01 2.07e-01 1.88e-01
MicroRNA (miRNA) biogenesis 24 3.57e-01 4.63e-01 0.14700 0.021200 1.45e-01 8.57e-01 2.18e-01
Insulin processing 20 3.59e-01 4.65e-01 0.23500 0.169000 1.63e-01 1.90e-01 2.07e-01
PKMTs methylate histone lysines 44 3.60e-01 4.66e-01 0.09800 -0.098000 3.52e-04 2.61e-01 9.97e-01
FRS-mediated FGFR1 signaling 14 3.61e-01 4.66e-01 0.24800 0.219000 1.16e-01 1.56e-01 4.52e-01
cGMP effects 12 3.61e-01 4.66e-01 0.30100 0.225000 2.00e-01 1.77e-01 2.31e-01
SLBP independent Processing of Histone Pre-mRNAs 10 3.64e-01 4.70e-01 0.16900 0.070300 -1.54e-01 7.00e-01 4.00e-01
HCMV Early Events 74 3.66e-01 4.72e-01 0.10800 0.094800 5.07e-02 1.58e-01 4.51e-01
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 14 3.67e-01 4.73e-01 0.25700 0.136000 2.18e-01 3.80e-01 1.57e-01
Synthesis of bile acids and bile salts 24 3.70e-01 4.76e-01 0.17600 0.069100 1.62e-01 5.58e-01 1.70e-01
Regulation of beta-cell development 19 3.70e-01 4.76e-01 0.14000 -0.013000 1.39e-01 9.22e-01 2.94e-01
Activation of NMDA receptors and postsynaptic events 58 3.71e-01 4.77e-01 0.13500 0.089100 1.01e-01 2.40e-01 1.82e-01
SUMOylation of transcription factors 16 3.72e-01 4.77e-01 0.23900 0.126000 2.03e-01 3.84e-01 1.59e-01
ECM proteoglycans 34 3.75e-01 4.80e-01 0.16800 0.094800 1.38e-01 3.39e-01 1.63e-01
ADORA2B mediated anti-inflammatory cytokines production 72 3.75e-01 4.80e-01 0.10800 0.050700 9.49e-02 4.57e-01 1.64e-01
MET activates PTK2 signaling 15 3.76e-01 4.80e-01 0.22400 0.204000 9.22e-02 1.71e-01 5.36e-01
Downstream signaling of activated FGFR2 19 3.76e-01 4.80e-01 0.12300 0.114000 -4.48e-02 3.89e-01 7.35e-01
Nonhomologous End-Joining (NHEJ) 42 3.79e-01 4.85e-01 0.15100 0.086800 1.23e-01 3.31e-01 1.66e-01
Mismatch Repair 15 3.80e-01 4.85e-01 0.23200 -0.106000 -2.06e-01 4.77e-01 1.67e-01
Cobalamin (Cbl, vitamin B12) transport and metabolism 17 3.82e-01 4.87e-01 0.19400 -0.062900 -1.84e-01 6.53e-01 1.90e-01
RNA Polymerase III Transcription Initiation 36 3.85e-01 4.90e-01 0.14900 -0.132000 -6.85e-02 1.70e-01 4.77e-01
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 11 3.87e-01 4.92e-01 0.15400 -0.136000 7.20e-02 4.35e-01 6.79e-01
NRAGE signals death through JNK 52 3.88e-01 4.92e-01 0.08060 -0.010800 7.99e-02 8.93e-01 3.19e-01
Gene Silencing by RNA 88 3.88e-01 4.92e-01 0.07930 0.077000 1.91e-02 2.12e-01 7.57e-01
Acyl chain remodelling of PG 11 3.88e-01 4.92e-01 0.30100 0.229000 1.95e-01 1.88e-01 2.62e-01
PECAM1 interactions 12 3.88e-01 4.92e-01 0.14200 -0.100000 1.01e-01 5.49e-01 5.44e-01
Dectin-2 family 19 3.95e-01 5.01e-01 0.21200 0.112000 1.81e-01 3.99e-01 1.73e-01
Signaling by PDGFR in disease 19 3.96e-01 5.01e-01 0.22800 0.171000 1.51e-01 1.98e-01 2.54e-01
Interleukin-2 family signaling 38 3.97e-01 5.01e-01 0.13000 0.045400 1.22e-01 6.28e-01 1.94e-01
Transport of Mature Transcript to Cytoplasm 81 3.97e-01 5.02e-01 0.09350 -0.038100 -8.54e-02 5.53e-01 1.84e-01
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 14 3.99e-01 5.03e-01 0.25300 -0.143000 -2.08e-01 3.55e-01 1.77e-01
Purine salvage 12 3.99e-01 5.03e-01 0.28700 0.202000 2.04e-01 2.25e-01 2.21e-01
Transcription-Coupled Nucleotide Excision Repair (TC-NER) 78 4.02e-01 5.07e-01 0.05490 -0.036300 4.12e-02 5.80e-01 5.29e-01
E2F mediated regulation of DNA replication 22 4.04e-01 5.08e-01 0.13800 -0.010900 -1.37e-01 9.29e-01 2.65e-01
Post NMDA receptor activation events 48 4.04e-01 5.08e-01 0.12500 0.057100 1.11e-01 4.94e-01 1.82e-01
A tetrasaccharide linker sequence is required for GAG synthesis 17 4.06e-01 5.09e-01 0.20000 -0.183000 -7.90e-02 1.91e-01 5.73e-01
Deposition of new CENPA-containing nucleosomes at the centromere 40 4.06e-01 5.09e-01 0.10100 0.101000 7.08e-03 2.69e-01 9.38e-01
Nucleosome assembly 40 4.06e-01 5.09e-01 0.10100 0.101000 7.08e-03 2.69e-01 9.38e-01
Signaling by ROBO receptors 198 4.08e-01 5.11e-01 0.03440 -0.027000 2.13e-02 5.12e-01 6.05e-01
Visual phototransduction 59 4.11e-01 5.15e-01 0.06320 -0.034800 5.28e-02 6.44e-01 4.83e-01
Vitamin B5 (pantothenate) metabolism 17 4.12e-01 5.15e-01 0.23400 0.151000 1.79e-01 2.81e-01 2.00e-01
Synthesis of PIPs at the Golgi membrane 16 4.14e-01 5.18e-01 0.16500 0.021700 1.63e-01 8.81e-01 2.58e-01
Downregulation of SMAD2/3:SMAD4 transcriptional activity 23 4.16e-01 5.18e-01 0.14100 0.024300 1.39e-01 8.40e-01 2.47e-01
Deadenylation-dependent mRNA decay 53 4.16e-01 5.18e-01 0.08560 0.085500 4.25e-03 2.82e-01 9.57e-01
Other semaphorin interactions 16 4.16e-01 5.18e-01 0.22400 0.117000 1.91e-01 4.20e-01 1.85e-01
Signaling by Retinoic Acid 31 4.16e-01 5.18e-01 0.09170 -0.031300 8.62e-02 7.63e-01 4.06e-01
Polo-like kinase mediated events 15 4.17e-01 5.18e-01 0.13600 -0.036100 1.31e-01 8.09e-01 3.81e-01
DNA Damage Bypass 47 4.19e-01 5.21e-01 0.09390 -0.009840 -9.34e-02 9.07e-01 2.68e-01
Non-integrin membrane-ECM interactions 37 4.20e-01 5.21e-01 0.15500 0.123000 9.54e-02 1.97e-01 3.16e-01
Nef mediated downregulation of MHC class I complex cell surface expression 10 4.26e-01 5.29e-01 0.22200 0.052800 2.16e-01 7.73e-01 2.37e-01
mRNA Capping 29 4.27e-01 5.29e-01 0.15500 0.069100 1.38e-01 5.19e-01 1.97e-01
Metabolism of amino acids and derivatives 323 4.28e-01 5.30e-01 0.03070 0.030400 -4.36e-03 3.48e-01 8.93e-01
Post-translational modification: synthesis of GPI-anchored proteins 56 4.29e-01 5.31e-01 0.08630 0.011200 8.56e-02 8.85e-01 2.68e-01
Homology Directed Repair 110 4.30e-01 5.32e-01 0.09110 -0.064600 -6.42e-02 2.42e-01 2.45e-01
ABC transporters in lipid homeostasis 14 4.37e-01 5.39e-01 0.25200 -0.176000 -1.81e-01 2.54e-01 2.41e-01
HS-GAG degradation 16 4.39e-01 5.41e-01 0.19200 0.070200 1.78e-01 6.27e-01 2.16e-01
Unblocking of NMDA receptors, glutamate binding and activation 12 4.39e-01 5.41e-01 0.26800 -0.171000 -2.07e-01 3.05e-01 2.15e-01
Constitutive Signaling by Aberrant PI3K in Cancer 53 4.44e-01 5.47e-01 0.09900 0.094400 2.96e-02 2.34e-01 7.09e-01
Sulfur amino acid metabolism 22 4.47e-01 5.49e-01 0.10100 -0.046200 8.93e-02 7.07e-01 4.68e-01
PI-3K cascade:FGFR2 12 4.47e-01 5.49e-01 0.13500 0.066200 -1.18e-01 6.91e-01 4.80e-01
Negative regulation of NMDA receptor-mediated neuronal transmission 14 4.48e-01 5.50e-01 0.24500 -0.157000 -1.89e-01 3.09e-01 2.22e-01
RHO GTPases Activate Formins 117 4.52e-01 5.55e-01 0.04590 -0.013200 4.40e-02 8.05e-01 4.11e-01
Translation 294 4.53e-01 5.55e-01 0.03070 0.005180 -3.02e-02 8.79e-01 3.73e-01
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 38 4.55e-01 5.57e-01 0.11200 -0.029300 -1.08e-01 7.55e-01 2.50e-01
RUNX3 regulates p14-ARF 10 4.55e-01 5.57e-01 0.20000 0.030800 1.98e-01 8.66e-01 2.79e-01
Activation of RAC1 11 4.61e-01 5.63e-01 0.27400 0.205000 1.82e-01 2.40e-01 2.95e-01
G1/S-Specific Transcription 29 4.64e-01 5.67e-01 0.11100 -0.010100 -1.11e-01 9.25e-01 3.02e-01
Activation of BH3-only proteins 30 4.65e-01 5.67e-01 0.12800 0.038500 1.22e-01 7.15e-01 2.47e-01
Interleukin receptor SHC signaling 23 4.67e-01 5.70e-01 0.15300 0.055100 1.43e-01 6.47e-01 2.36e-01
Signaling by ERBB2 ECD mutants 15 4.69e-01 5.71e-01 0.22000 0.183000 1.22e-01 2.19e-01 4.12e-01
Telomere Maintenance 80 4.70e-01 5.72e-01 0.06000 -0.059800 4.47e-03 3.55e-01 9.45e-01
Regulation of KIT signaling 15 4.74e-01 5.75e-01 0.15800 0.022400 1.56e-01 8.80e-01 2.94e-01
DNA Replication Pre-Initiation 82 4.74e-01 5.75e-01 0.08260 0.032400 7.59e-02 6.12e-01 2.35e-01
Glucagon-type ligand receptors 20 4.74e-01 5.75e-01 0.14600 0.142000 3.41e-02 2.70e-01 7.92e-01
Synthesis of IP2, IP, and Ins in the cytosol 13 4.74e-01 5.75e-01 0.20800 0.191000 8.30e-02 2.34e-01 6.04e-01
IRS-related events triggered by IGF1R 35 4.74e-01 5.75e-01 0.14200 0.119000 7.74e-02 2.22e-01 4.28e-01
PI-3K cascade:FGFR4 10 4.79e-01 5.80e-01 0.20500 0.200000 4.77e-02 2.74e-01 7.94e-01
HSF1 activation 26 4.80e-01 5.80e-01 0.17300 0.131000 1.12e-01 2.46e-01 3.22e-01
Regulation of TP53 Activity through Phosphorylation 88 4.89e-01 5.91e-01 0.09340 -0.062700 -6.92e-02 3.09e-01 2.62e-01
Molecules associated with elastic fibres 21 4.91e-01 5.92e-01 0.15000 0.047900 1.42e-01 7.04e-01 2.60e-01
G alpha (s) signalling events 137 4.91e-01 5.93e-01 0.07320 0.044800 5.78e-02 3.65e-01 2.43e-01
Maturation of nucleoprotein 10 4.92e-01 5.93e-01 0.22800 -0.211000 -8.77e-02 2.48e-01 6.31e-01
Downstream signaling of activated FGFR1 20 4.93e-01 5.94e-01 0.16000 0.148000 5.94e-02 2.51e-01 6.45e-01
Cohesin Loading onto Chromatin 10 4.93e-01 5.94e-01 0.26900 0.164000 2.13e-01 3.70e-01 2.43e-01
Metal ion SLC transporters 21 4.95e-01 5.95e-01 0.19000 0.136000 1.33e-01 2.82e-01 2.91e-01
RNA Polymerase III Chain Elongation 18 4.98e-01 5.98e-01 0.19600 -0.160000 -1.13e-01 2.41e-01 4.05e-01
Establishment of Sister Chromatid Cohesion 11 5.00e-01 5.99e-01 0.18500 0.182000 3.66e-02 2.97e-01 8.33e-01
NCAM signaling for neurite out-growth 43 5.01e-01 6.01e-01 0.09260 -0.017000 -9.10e-02 8.47e-01 3.02e-01
IGF1R signaling cascade 36 5.02e-01 6.01e-01 0.14200 0.109000 9.19e-02 2.60e-01 3.40e-01
Phase 2 - plateau phase 11 5.03e-01 6.02e-01 0.20600 -0.068700 -1.94e-01 6.93e-01 2.66e-01
SUMOylation of DNA replication proteins 46 5.06e-01 6.04e-01 0.11600 -0.058800 -9.95e-02 4.90e-01 2.43e-01
Downregulation of ERBB2:ERBB3 signaling 12 5.06e-01 6.04e-01 0.16700 0.021500 1.66e-01 8.97e-01 3.20e-01
SUMO E3 ligases SUMOylate target proteins 159 5.15e-01 6.15e-01 0.03640 -0.035000 9.73e-03 4.46e-01 8.32e-01
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) 12 5.16e-01 6.15e-01 0.23100 0.129000 1.91e-01 4.39e-01 2.51e-01
Amino acid transport across the plasma membrane 23 5.17e-01 6.15e-01 0.17400 0.133000 1.13e-01 2.71e-01 3.50e-01
Caspase-mediated cleavage of cytoskeletal proteins 12 5.17e-01 6.15e-01 0.14200 -0.014700 1.41e-01 9.30e-01 3.96e-01
Centrosome maturation 80 5.17e-01 6.15e-01 0.08210 -0.073500 -3.66e-02 2.56e-01 5.72e-01
Recruitment of mitotic centrosome proteins and complexes 80 5.17e-01 6.15e-01 0.08210 -0.073500 -3.66e-02 2.56e-01 5.72e-01
Cellular response to heat stress 93 5.20e-01 6.16e-01 0.04440 0.019500 -3.99e-02 7.45e-01 5.06e-01
Lewis blood group biosynthesis 13 5.20e-01 6.16e-01 0.12500 -0.120000 3.54e-02 4.54e-01 8.25e-01
Purine catabolism 16 5.20e-01 6.17e-01 0.19100 0.165000 9.57e-02 2.54e-01 5.08e-01
Epigenetic regulation of gene expression 100 5.25e-01 6.21e-01 0.08240 0.052400 6.35e-02 3.65e-01 2.72e-01
Lysine catabolism 11 5.26e-01 6.22e-01 0.15100 -0.007730 1.51e-01 9.65e-01 3.86e-01
Cyclin A/B1/B2 associated events during G2/M transition 24 5.27e-01 6.23e-01 0.14200 0.057200 1.30e-01 6.28e-01 2.70e-01
Miscellaneous transport and binding events 20 5.28e-01 6.24e-01 0.17900 0.105000 1.44e-01 4.14e-01 2.63e-01
Mitochondrial translation elongation 91 5.34e-01 6.30e-01 0.05440 0.001290 5.44e-02 9.83e-01 3.70e-01
Nephrin family interactions 18 5.35e-01 6.30e-01 0.13500 -0.133000 -2.26e-02 3.30e-01 8.68e-01
mitochondrial fatty acid beta-oxidation of saturated fatty acids 11 5.36e-01 6.31e-01 0.24700 0.176000 1.74e-01 3.13e-01 3.18e-01
Processing of SMDT1 15 5.37e-01 6.32e-01 0.17400 0.161000 6.68e-02 2.80e-01 6.54e-01
Synthesis of PE 12 5.37e-01 6.32e-01 0.18800 -0.063600 -1.77e-01 7.03e-01 2.89e-01
Signaling by BMP 21 5.39e-01 6.33e-01 0.09230 0.085300 -3.52e-02 4.99e-01 7.80e-01
O-linked glycosylation 81 5.42e-01 6.34e-01 0.07600 -0.069500 -3.08e-02 2.79e-01 6.32e-01
Base Excision Repair 58 5.42e-01 6.34e-01 0.07690 -0.075100 -1.65e-02 3.23e-01 8.28e-01
Recruitment of NuMA to mitotic centrosomes 79 5.42e-01 6.34e-01 0.08310 -0.072000 -4.15e-02 2.69e-01 5.23e-01
IRS-mediated signalling 34 5.42e-01 6.34e-01 0.12500 0.109000 6.08e-02 2.70e-01 5.39e-01
The phototransduction cascade 26 5.42e-01 6.34e-01 0.13400 -0.122000 -5.42e-02 2.80e-01 6.32e-01
Mitochondrial translation initiation 91 5.43e-01 6.34e-01 0.05660 0.005830 5.63e-02 9.23e-01 3.54e-01
Prolactin receptor signaling 11 5.43e-01 6.34e-01 0.18800 0.180000 5.62e-02 3.02e-01 7.47e-01
Regulation of pyruvate dehydrogenase (PDH) complex 15 5.48e-01 6.40e-01 0.20400 0.159000 1.28e-01 2.87e-01 3.89e-01
Long-term potentiation 14 5.51e-01 6.43e-01 0.17100 -0.058300 -1.60e-01 7.06e-01 2.99e-01
Biosynthesis of DHA-derived SPMs 14 5.55e-01 6.47e-01 0.20900 0.130000 1.63e-01 3.99e-01 2.91e-01
Signaling by Activin 10 5.59e-01 6.50e-01 0.14300 0.021400 -1.41e-01 9.07e-01 4.39e-01
Neurexins and neuroligins 35 5.61e-01 6.52e-01 0.10600 -0.099800 -3.54e-02 3.07e-01 7.17e-01
Interleukin-2 signaling 11 5.64e-01 6.55e-01 0.11700 -0.064900 9.78e-02 7.09e-01 5.75e-01
Gap-filling DNA repair synthesis and ligation in TC-NER 64 5.65e-01 6.56e-01 0.05080 -0.047000 1.94e-02 5.16e-01 7.88e-01
Gamma carboxylation, hypusine formation and arylsulfatase activation 34 5.65e-01 6.56e-01 0.09460 0.017400 9.30e-02 8.61e-01 3.48e-01
Protein methylation 15 5.67e-01 6.57e-01 0.18100 0.087700 1.58e-01 5.57e-01 2.88e-01
Mitochondrial protein import 64 5.68e-01 6.57e-01 0.09680 0.073700 6.28e-02 3.08e-01 3.85e-01
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 17 5.72e-01 6.62e-01 0.18800 0.134000 1.32e-01 3.39e-01 3.45e-01
SUMOylation 165 5.75e-01 6.64e-01 0.03550 -0.035400 3.20e-03 4.33e-01 9.44e-01
Mitotic G1 phase and G1/S transition 148 5.75e-01 6.64e-01 0.05350 0.021700 4.90e-02 6.49e-01 3.04e-01
Interleukin-20 family signaling 17 5.80e-01 6.69e-01 0.18600 0.129000 1.33e-01 3.56e-01 3.42e-01
Mitochondrial translation 97 5.81e-01 6.69e-01 0.06470 0.025200 5.95e-02 6.68e-01 3.11e-01
TNF signaling 43 5.83e-01 6.72e-01 0.07250 0.000548 7.25e-02 9.95e-01 4.11e-01
Repression of WNT target genes 14 5.84e-01 6.72e-01 0.17900 -0.159000 -8.25e-02 3.03e-01 5.93e-01
Transcriptional regulation of pluripotent stem cells 20 5.88e-01 6.76e-01 0.15500 0.079700 1.33e-01 5.37e-01 3.03e-01
NOTCH2 intracellular domain regulates transcription 11 5.89e-01 6.77e-01 0.22600 0.169000 1.50e-01 3.31e-01 3.88e-01
Acyl chain remodelling of PS 14 5.92e-01 6.79e-01 0.17500 0.156000 7.81e-02 3.11e-01 6.13e-01
Termination of O-glycan biosynthesis 16 5.92e-01 6.79e-01 0.09270 -0.075800 5.34e-02 6.00e-01 7.11e-01
Synaptic adhesion-like molecules 15 5.94e-01 6.81e-01 0.09840 -0.088300 4.34e-02 5.54e-01 7.71e-01
Protein-protein interactions at synapses 55 5.95e-01 6.81e-01 0.05900 -0.058700 6.15e-03 4.52e-01 9.37e-01
Regulation of FOXO transcriptional activity by acetylation 10 6.00e-01 6.86e-01 0.16400 0.029100 1.62e-01 8.73e-01 3.76e-01
AURKA Activation by TPX2 71 6.00e-01 6.86e-01 0.05450 -0.054500 3.48e-04 4.27e-01 9.96e-01
Condensation of Prometaphase Chromosomes 11 6.02e-01 6.87e-01 0.12100 -0.031800 1.16e-01 8.55e-01 5.04e-01
Cyclin D associated events in G1 47 6.03e-01 6.87e-01 0.09550 0.044700 8.44e-02 5.96e-01 3.17e-01
G1 Phase 47 6.03e-01 6.87e-01 0.09550 0.044700 8.44e-02 5.96e-01 3.17e-01
Reproduction 80 6.10e-01 6.95e-01 0.08130 0.060800 5.39e-02 3.47e-01 4.04e-01
Anchoring of the basal body to the plasma membrane 96 6.10e-01 6.95e-01 0.06740 -0.033300 -5.86e-02 5.73e-01 3.21e-01
Mitochondrial Fatty Acid Beta-Oxidation 36 6.11e-01 6.95e-01 0.07170 -0.006100 7.15e-02 9.50e-01 4.58e-01
Netrin-1 signaling 40 6.13e-01 6.97e-01 0.07610 0.007720 7.57e-02 9.33e-01 4.07e-01
Zinc transporters 14 6.14e-01 6.97e-01 0.19400 0.140000 1.34e-01 3.64e-01 3.87e-01
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 25 6.15e-01 6.98e-01 0.10300 0.020600 1.01e-01 8.58e-01 3.82e-01
Regulation of expression of SLITs and ROBOs 158 6.16e-01 6.99e-01 0.04320 -0.041600 -1.15e-02 3.66e-01 8.04e-01
Mitochondrial translation termination 91 6.19e-01 7.02e-01 0.05040 0.005710 5.01e-02 9.25e-01 4.09e-01
Phase 4 - resting membrane potential 10 6.21e-01 7.03e-01 0.21000 0.178000 1.11e-01 3.29e-01 5.45e-01
Synthesis, secretion, and deacylation of Ghrelin 11 6.21e-01 7.03e-01 0.10800 0.053500 -9.42e-02 7.59e-01 5.89e-01
Kinesins 39 6.28e-01 7.10e-01 0.06260 -0.061000 1.38e-02 5.09e-01 8.82e-01
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 37 6.29e-01 7.10e-01 0.11300 0.090200 6.81e-02 3.43e-01 4.74e-01
Regulation of innate immune responses to cytosolic DNA 14 6.35e-01 7.16e-01 0.09580 -0.087000 3.99e-02 5.73e-01 7.96e-01
Formation of Incision Complex in GG-NER 43 6.37e-01 7.19e-01 0.09870 0.083600 5.24e-02 3.43e-01 5.52e-01
SHC-mediated cascade:FGFR2 12 6.38e-01 7.19e-01 0.11000 0.026500 -1.06e-01 8.74e-01 5.23e-01
Nuclear Envelope Breakdown 53 6.40e-01 7.20e-01 0.06140 -0.003660 -6.13e-02 9.63e-01 4.40e-01
Nicotinamide salvaging 14 6.42e-01 7.22e-01 0.13900 -0.133000 -3.70e-02 3.87e-01 8.10e-01
Viral Messenger RNA Synthesis 44 6.43e-01 7.23e-01 0.10300 -0.068100 -7.77e-02 4.35e-01 3.72e-01
Pregnenolone biosynthesis 10 6.44e-01 7.24e-01 0.11800 -0.031000 1.14e-01 8.65e-01 5.34e-01
Aflatoxin activation and detoxification 14 6.57e-01 7.37e-01 0.17600 0.138000 1.09e-01 3.71e-01 4.79e-01
FGFR2 alternative splicing 25 6.57e-01 7.37e-01 0.10400 0.031900 9.92e-02 7.83e-01 3.91e-01
Glutamate Neurotransmitter Release Cycle 20 6.64e-01 7.43e-01 0.07490 0.035800 -6.58e-02 7.82e-01 6.11e-01
Ras activation upon Ca2+ influx through NMDA receptor 15 6.67e-01 7.46e-01 0.14300 -0.057700 -1.31e-01 6.99e-01 3.79e-01
Transcriptional Regulation by VENTX 38 6.67e-01 7.46e-01 0.06100 -0.060300 9.35e-03 5.20e-01 9.21e-01
Sema3A PAK dependent Axon repulsion 16 6.69e-01 7.47e-01 0.15400 0.130000 8.28e-02 3.70e-01 5.66e-01
Class A/1 (Rhodopsin-like receptors) 166 6.73e-01 7.51e-01 0.04280 0.017300 3.91e-02 7.01e-01 3.84e-01
PI-3K cascade:FGFR1 12 6.74e-01 7.51e-01 0.16400 0.147000 7.40e-02 3.79e-01 6.57e-01
Nicotinate metabolism 25 6.78e-01 7.55e-01 0.06430 -0.054100 3.48e-02 6.40e-01 7.63e-01
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion 14 6.80e-01 7.57e-01 0.09560 -0.093600 1.99e-02 5.44e-01 8.98e-01
RNA Polymerase III Transcription Initiation From Type 3 Promoter 28 6.81e-01 7.57e-01 0.11900 -0.093400 -7.41e-02 3.92e-01 4.97e-01
Regulation of TNFR1 signaling 34 6.82e-01 7.58e-01 0.07860 -0.077000 -1.59e-02 4.37e-01 8.72e-01
Cell Cycle Checkpoints 258 6.84e-01 7.60e-01 0.03830 0.022200 3.13e-02 5.40e-01 3.87e-01
Inactivation, recovery and regulation of the phototransduction cascade 25 6.85e-01 7.60e-01 0.09650 -0.092800 -2.66e-02 4.22e-01 8.18e-01
Meiosis 68 6.86e-01 7.60e-01 0.07740 0.054200 5.53e-02 4.39e-01 4.31e-01
CDC6 association with the ORC:origin complex 11 6.86e-01 7.60e-01 0.09390 0.062700 -6.99e-02 7.19e-01 6.88e-01
SHC-mediated cascade:FGFR4 10 6.89e-01 7.62e-01 0.16400 0.152000 6.11e-02 4.04e-01 7.38e-01
Processing and activation of SUMO 10 6.91e-01 7.64e-01 0.19700 0.151000 1.27e-01 4.08e-01 4.86e-01
mRNA decay by 5' to 3' exoribonuclease 15 6.92e-01 7.65e-01 0.07990 -0.063600 4.83e-02 6.70e-01 7.46e-01
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) 10 6.93e-01 7.65e-01 0.11900 0.006330 -1.19e-01 9.72e-01 5.14e-01
APC/C:Cdc20 mediated degradation of Cyclin B 24 7.01e-01 7.74e-01 0.12600 0.091300 8.70e-02 4.39e-01 4.61e-01
Neurotransmitter release cycle 38 7.02e-01 7.74e-01 0.07770 0.074000 2.38e-02 4.30e-01 8.00e-01
Cytochrome P450 - arranged by substrate type 32 7.03e-01 7.75e-01 0.10400 0.060500 8.51e-02 5.53e-01 4.05e-01
Transport of inorganic cations/anions and amino acids/oligopeptides 79 7.11e-01 7.82e-01 0.06380 0.034500 5.37e-02 5.96e-01 4.09e-01
Loss of Nlp from mitotic centrosomes 68 7.12e-01 7.82e-01 0.05660 -0.054000 -1.69e-02 4.41e-01 8.09e-01
Loss of proteins required for interphase microtubule organization from the centrosome 68 7.12e-01 7.82e-01 0.05660 -0.054000 -1.69e-02 4.41e-01 8.09e-01
Cellular hexose transport 15 7.13e-01 7.83e-01 0.12600 -0.045500 -1.18e-01 7.60e-01 4.30e-01
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 31 7.16e-01 7.86e-01 0.05880 -0.014500 5.70e-02 8.89e-01 5.83e-01
Translesion Synthesis by POLH 18 7.22e-01 7.91e-01 0.13100 -0.070400 -1.10e-01 6.05e-01 4.19e-01
Global Genome Nucleotide Excision Repair (GG-NER) 84 7.23e-01 7.92e-01 0.03400 -0.032100 1.13e-02 6.11e-01 8.58e-01
FOXO-mediated transcription of cell cycle genes 15 7.25e-01 7.94e-01 0.07670 -0.036100 6.77e-02 8.09e-01 6.50e-01
CLEC7A (Dectin-1) induces NFAT activation 11 7.26e-01 7.94e-01 0.09080 -0.082600 3.77e-02 6.35e-01 8.29e-01
SLC transporter disorders 75 7.29e-01 7.97e-01 0.04550 0.045100 5.72e-03 4.99e-01 9.32e-01
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation 10 7.32e-01 8.00e-01 0.13200 0.029100 1.29e-01 8.74e-01 4.79e-01
IL-6-type cytokine receptor ligand interactions 12 7.38e-01 8.05e-01 0.10300 0.103000 2.34e-04 5.38e-01 9.99e-01
Mitotic Prometaphase 184 7.42e-01 8.09e-01 0.04200 -0.029100 -3.02e-02 4.96e-01 4.80e-01
TRAF6 mediated IRF7 activation 15 7.45e-01 8.12e-01 0.11800 0.043100 1.10e-01 7.73e-01 4.61e-01
Blood group systems biosynthesis 17 7.46e-01 8.12e-01 0.13000 0.073600 1.07e-01 5.99e-01 4.46e-01
PI3K Cascade 30 7.48e-01 8.14e-01 0.10000 0.078100 6.32e-02 4.59e-01 5.49e-01
Synthesis of PA 32 7.49e-01 8.14e-01 0.08350 0.076000 3.45e-02 4.57e-01 7.36e-01
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 104 7.53e-01 8.18e-01 0.05370 -0.034400 -4.12e-02 5.44e-01 4.68e-01
Diseases associated with N-glycosylation of proteins 17 7.58e-01 8.23e-01 0.11800 0.056500 1.04e-01 6.87e-01 4.58e-01
Interleukin-7 signaling 21 7.60e-01 8.24e-01 0.11900 0.082200 8.55e-02 5.14e-01 4.98e-01
FGFR2 mutant receptor activation 22 7.60e-01 8.24e-01 0.05770 -0.030600 4.89e-02 8.04e-01 6.91e-01
G0 and Early G1 27 7.62e-01 8.25e-01 0.06210 0.061900 -4.16e-03 5.77e-01 9.70e-01
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 27 7.64e-01 8.27e-01 0.07080 0.010300 7.01e-02 9.26e-01 5.28e-01
Phosphorylation of the APC/C 20 7.67e-01 8.30e-01 0.10800 0.093800 5.27e-02 4.68e-01 6.83e-01
Lysosphingolipid and LPA receptors 11 7.76e-01 8.38e-01 0.09560 -0.095500 3.57e-03 5.83e-01 9.84e-01
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 23 7.86e-01 8.48e-01 0.07980 0.021400 7.69e-02 8.59e-01 5.23e-01
Regulation of PLK1 Activity at G2/M Transition 86 7.87e-01 8.48e-01 0.02870 -0.026800 1.02e-02 6.67e-01 8.70e-01
Regulation of TP53 Activity through Methylation 19 7.87e-01 8.48e-01 0.11300 -0.068200 -9.03e-02 6.07e-01 4.95e-01
KSRP (KHSRP) binds and destabilizes mRNA 17 7.89e-01 8.49e-01 0.06390 0.059400 -2.34e-02 6.71e-01 8.67e-01
Signaling by FGFR2 in disease 32 7.94e-01 8.55e-01 0.07890 0.069100 3.81e-02 4.99e-01 7.09e-01
TP53 Regulates Transcription of Death Receptors and Ligands 12 7.97e-01 8.57e-01 0.11800 0.109000 4.51e-02 5.14e-01 7.87e-01
Dual incision in TC-NER 65 7.98e-01 8.57e-01 0.03020 -0.017600 2.45e-02 8.06e-01 7.33e-01
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 17 7.98e-01 8.57e-01 0.08560 -0.017900 -8.37e-02 8.98e-01 5.50e-01
STING mediated induction of host immune responses 15 8.01e-01 8.59e-01 0.12500 0.083100 9.40e-02 5.77e-01 5.29e-01
Organelle biogenesis and maintenance 268 8.05e-01 8.61e-01 0.02050 0.020300 3.25e-03 5.68e-01 9.27e-01
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects 17 8.05e-01 8.61e-01 0.06260 -0.059800 1.87e-02 6.70e-01 8.94e-01
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) 17 8.05e-01 8.61e-01 0.06260 -0.059800 1.87e-02 6.70e-01 8.94e-01
SHC-mediated cascade:FGFR1 12 8.05e-01 8.61e-01 0.13700 0.107000 8.51e-02 5.21e-01 6.10e-01
Acetylcholine Neurotransmitter Release Cycle 11 8.09e-01 8.64e-01 0.13900 -0.081200 -1.13e-01 6.41e-01 5.18e-01
Inactivation of APC/C via direct inhibition of the APC/C complex 21 8.12e-01 8.66e-01 0.05370 0.049700 -2.03e-02 6.93e-01 8.72e-01
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 21 8.12e-01 8.66e-01 0.05370 0.049700 -2.03e-02 6.93e-01 8.72e-01
TP53 Regulates Transcription of Caspase Activators and Caspases 12 8.15e-01 8.69e-01 0.07060 0.025700 -6.58e-02 8.78e-01 6.93e-01
Serotonin Neurotransmitter Release Cycle 14 8.16e-01 8.69e-01 0.11000 -0.097800 -5.10e-02 5.26e-01 7.41e-01
Glyoxylate metabolism and glycine degradation 24 8.19e-01 8.72e-01 0.06530 0.064500 1.04e-02 5.85e-01 9.30e-01
G2/M DNA damage checkpoint 67 8.21e-01 8.73e-01 0.02870 0.012600 -2.58e-02 8.59e-01 7.15e-01
Transcription of E2F targets under negative control by DREAM complex 19 8.22e-01 8.73e-01 0.05980 0.059000 -9.69e-03 6.56e-01 9.42e-01
Voltage gated Potassium channels 24 8.27e-01 8.78e-01 0.05460 -0.004630 5.44e-02 9.69e-01 6.45e-01
Xenobiotics 11 8.29e-01 8.80e-01 0.08830 -0.006930 -8.80e-02 9.68e-01 6.13e-01
Fertilization 12 8.37e-01 8.87e-01 0.10800 0.097800 4.60e-02 5.58e-01 7.82e-01
Adherens junctions interactions 18 8.40e-01 8.90e-01 0.07550 0.018800 7.31e-02 8.90e-01 5.91e-01
GPCR ligand binding 231 8.42e-01 8.91e-01 0.02790 0.017500 2.18e-02 6.47e-01 5.69e-01
Regulation of RUNX1 Expression and Activity 18 8.43e-01 8.91e-01 0.08530 -0.077900 -3.49e-02 5.67e-01 7.97e-01
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 19 8.44e-01 8.91e-01 0.08880 -0.077000 -4.41e-02 5.61e-01 7.39e-01
Early Phase of HIV Life Cycle 14 8.44e-01 8.91e-01 0.10100 -0.047600 -8.94e-02 7.58e-01 5.63e-01
TRAF3-dependent IRF activation pathway 13 8.48e-01 8.95e-01 0.11700 0.080200 8.48e-02 6.17e-01 5.97e-01
Basigin interactions 22 8.49e-01 8.95e-01 0.08590 0.049900 6.99e-02 6.85e-01 5.70e-01
Dopamine Neurotransmitter Release Cycle 19 8.52e-01 8.98e-01 0.07490 -0.024200 -7.08e-02 8.55e-01 5.93e-01
Aberrant regulation of mitotic exit in cancer due to RB1 defects 20 8.53e-01 8.98e-01 0.08910 0.072000 5.25e-02 5.77e-01 6.84e-01
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 17 8.54e-01 8.98e-01 0.10000 -0.069700 -7.18e-02 6.19e-01 6.08e-01
GABA synthesis, release, reuptake and degradation 13 8.56e-01 8.99e-01 0.05850 0.023400 -5.37e-02 8.84e-01 7.38e-01
mRNA 3'-end processing 56 8.60e-01 9.04e-01 0.03580 0.003740 3.56e-02 9.61e-01 6.45e-01
Synthesis of PIPs at the early endosome membrane 16 8.62e-01 9.04e-01 0.07660 0.022200 7.33e-02 8.78e-01 6.12e-01
Class B/2 (Secretin family receptors) 55 8.68e-01 9.10e-01 0.04160 0.013600 3.93e-02 8.61e-01 6.14e-01
Glutamate and glutamine metabolism 12 8.71e-01 9.13e-01 0.07360 -0.007330 -7.33e-02 9.65e-01 6.60e-01
SUMOylation of DNA methylation proteins 16 8.76e-01 9.16e-01 0.05500 -0.054600 6.17e-03 7.05e-01 9.66e-01
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 91 8.76e-01 9.16e-01 0.03940 -0.029600 -2.60e-02 6.25e-01 6.69e-01
Amplification of signal from the kinetochores 91 8.76e-01 9.16e-01 0.03940 -0.029600 -2.60e-02 6.25e-01 6.69e-01
TRP channels 17 8.77e-01 9.16e-01 0.06600 -0.014700 -6.44e-02 9.16e-01 6.46e-01
WNT ligand biogenesis and trafficking 21 8.78e-01 9.16e-01 0.08120 0.061300 5.33e-02 6.27e-01 6.72e-01
RNA Polymerase II Transcription Termination 65 8.80e-01 9.18e-01 0.03960 0.017200 3.57e-02 8.10e-01 6.19e-01
Inhibition of replication initiation of damaged DNA by RB1/E2F1 13 8.81e-01 9.18e-01 0.07240 0.071100 1.36e-02 6.57e-01 9.32e-01
TICAM1-dependent activation of IRF3/IRF7 12 8.84e-01 9.21e-01 0.09790 0.052400 8.27e-02 7.53e-01 6.20e-01
CRMPs in Sema3A signaling 14 8.87e-01 9.23e-01 0.04760 -0.039600 2.64e-02 7.98e-01 8.64e-01
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14 8.92e-01 9.27e-01 0.06740 0.065900 1.43e-02 6.69e-01 9.26e-01
G1/S Transition 130 8.97e-01 9.32e-01 0.02380 0.007930 2.24e-02 8.76e-01 6.59e-01
Synthesis of glycosylphosphatidylinositol (GPI) 17 9.01e-01 9.35e-01 0.06850 -0.062600 -2.79e-02 6.55e-01 8.42e-01
APC-Cdc20 mediated degradation of Nek2A 26 9.01e-01 9.35e-01 0.05720 0.051200 2.55e-02 6.52e-01 8.22e-01
RNA Polymerase III Transcription Termination 23 9.14e-01 9.48e-01 0.03360 0.031200 -1.26e-02 7.96e-01 9.16e-01
Defective B3GAT3 causes JDSSDHD 11 9.20e-01 9.53e-01 0.04490 -0.038000 2.38e-02 8.27e-01 8.91e-01
Metabolism of water-soluble vitamins and cofactors 110 9.23e-01 9.55e-01 0.01370 -0.009480 9.88e-03 8.64e-01 8.58e-01
Processing of Intronless Pre-mRNAs 19 9.24e-01 9.55e-01 0.03920 -0.004180 3.90e-02 9.75e-01 7.69e-01
Signaling by NTRK3 (TRKC) 15 9.24e-01 9.55e-01 0.07030 0.059100 3.79e-02 6.92e-01 7.99e-01
Regulation of FZD by ubiquitination 15 9.26e-01 9.55e-01 0.03650 0.022200 -2.91e-02 8.82e-01 8.46e-01
Activation of SMO 13 9.26e-01 9.55e-01 0.04620 -0.005640 4.58e-02 9.72e-01 7.75e-01
Competing endogenous RNAs (ceRNAs) regulate PTEN translation 11 9.30e-01 9.59e-01 0.06210 -0.015400 -6.02e-02 9.30e-01 7.30e-01
Branched-chain amino acid catabolism 21 9.33e-01 9.61e-01 0.03040 0.013200 -2.74e-02 9.17e-01 8.28e-01
Receptor-type tyrosine-protein phosphatases 11 9.35e-01 9.63e-01 0.05190 0.051800 2.60e-03 7.66e-01 9.88e-01
Processing of Capped Intronless Pre-mRNA 28 9.38e-01 9.65e-01 0.04830 0.029600 3.82e-02 7.86e-01 7.27e-01
Defective EXT1 causes exostoses 1, TRPS2 and CHDS 10 9.44e-01 9.66e-01 0.03950 -0.033900 2.02e-02 8.53e-01 9.12e-01
Defective EXT2 causes exostoses 2 10 9.44e-01 9.66e-01 0.03950 -0.033900 2.02e-02 8.53e-01 9.12e-01
Defective B4GALT7 causes EDS, progeroid type 11 9.44e-01 9.66e-01 0.05560 -0.014100 -5.38e-02 9.36e-01 7.57e-01
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 14 9.44e-01 9.66e-01 0.05890 -0.027900 -5.19e-02 8.57e-01 7.37e-01
Signaling by KIT in disease 20 9.45e-01 9.66e-01 0.02930 0.009510 -2.77e-02 9.41e-01 8.30e-01
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants 20 9.45e-01 9.66e-01 0.02930 0.009510 -2.77e-02 9.41e-01 8.30e-01
Aberrant regulation of mitotic cell cycle due to RB1 defects 36 9.46e-01 9.66e-01 0.01990 -0.014400 1.37e-02 8.81e-01 8.87e-01
Diseases of mitotic cell cycle 36 9.46e-01 9.66e-01 0.01990 -0.014400 1.37e-02 8.81e-01 8.87e-01
CASP8 activity is inhibited 11 9.47e-01 9.66e-01 0.03580 0.025600 -2.49e-02 8.83e-01 8.86e-01
Dimerization of procaspase-8 11 9.47e-01 9.66e-01 0.03580 0.025600 -2.49e-02 8.83e-01 8.86e-01
Regulation by c-FLIP 11 9.47e-01 9.66e-01 0.03580 0.025600 -2.49e-02 8.83e-01 8.86e-01
TNFR1-induced NFkappaB signaling pathway 25 9.50e-01 9.68e-01 0.02530 -0.024300 6.94e-03 8.33e-01 9.52e-01
Mitotic Spindle Checkpoint 108 9.51e-01 9.68e-01 0.02140 -0.012300 -1.75e-02 8.25e-01 7.53e-01
RNA Polymerase III Abortive And Retractive Initiation 41 9.52e-01 9.68e-01 0.03330 -0.028400 -1.74e-02 7.53e-01 8.47e-01
RNA Polymerase III Transcription 41 9.52e-01 9.68e-01 0.03330 -0.028400 -1.74e-02 7.53e-01 8.47e-01
S Phase 160 9.54e-01 9.69e-01 0.01670 -0.014100 -8.96e-03 7.58e-01 8.45e-01
Eicosanoid ligand-binding receptors 13 9.54e-01 9.69e-01 0.04490 -0.009710 -4.38e-02 9.52e-01 7.85e-01
DCC mediated attractive signaling 13 9.56e-01 9.70e-01 0.04490 0.011200 4.35e-02 9.44e-01 7.86e-01
PIWI-interacting RNA (piRNA) biogenesis 24 9.57e-01 9.70e-01 0.04450 0.031500 3.15e-02 7.89e-01 7.90e-01
Negative regulators of DDX58/IFIH1 signaling 34 9.63e-01 9.76e-01 0.02110 -0.000391 2.11e-02 9.97e-01 8.31e-01
Interleukin-35 Signalling 12 9.71e-01 9.83e-01 0.04690 -0.040600 -2.35e-02 8.08e-01 8.88e-01
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 20 9.74e-01 9.85e-01 0.03470 0.029700 1.80e-02 8.18e-01 8.89e-01
Regulation of PTEN mRNA translation 13 9.75e-01 9.86e-01 0.03520 -0.010400 -3.36e-02 9.48e-01 8.34e-01
IRF3-mediated induction of type I IFN 12 9.76e-01 9.86e-01 0.03230 -0.004800 -3.20e-02 9.77e-01 8.48e-01
Interaction between L1 and Ankyrins 20 9.78e-01 9.87e-01 0.02780 -0.009700 -2.60e-02 9.40e-01 8.40e-01
Defective B3GALT6 causes EDSP2 and SEMDJL1 11 9.79e-01 9.88e-01 0.03040 -0.030200 -3.57e-03 8.62e-01 9.84e-01
EML4 and NUDC in mitotic spindle formation 95 9.80e-01 9.88e-01 0.01410 -0.012000 -7.33e-03 8.40e-01 9.02e-01
Methylation 12 9.81e-01 9.89e-01 0.02610 -0.026000 -1.03e-03 8.76e-01 9.95e-01
Processing of DNA double-strand break ends 71 9.82e-01 9.89e-01 0.01260 -0.003610 -1.20e-02 9.58e-01 8.61e-01
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 16 9.83e-01 9.89e-01 0.03240 -0.018300 -2.67e-02 8.99e-01 8.53e-01
Synthesis of DNA 118 9.84e-01 9.89e-01 0.01200 -0.007820 -9.03e-03 8.83e-01 8.65e-01
Norepinephrine Neurotransmitter Release Cycle 14 9.87e-01 9.91e-01 0.03160 0.023400 2.12e-02 8.80e-01 8.91e-01
Collagen chain trimerization 27 9.91e-01 9.95e-01 0.01090 0.001650 -1.07e-02 9.88e-01 9.23e-01
DNA Replication 125 9.92e-01 9.95e-01 0.00514 0.005140 -4.02e-05 9.21e-01 9.99e-01
Signaling by NODAL 13 9.94e-01 9.95e-01 0.01090 0.008480 -6.81e-03 9.58e-01 9.66e-01
Nucleotide-like (purinergic) receptors 13 9.95e-01 9.95e-01 0.01540 -0.015000 -3.44e-03 9.25e-01 9.83e-01
Glutathione synthesis and recycling 10 9.95e-01 9.95e-01 0.01320 -0.012700 3.30e-03 9.44e-01 9.86e-01
Resolution of Sister Chromatid Cohesion 104 9.99e-01 9.99e-01 0.00214 0.001830 1.10e-03 9.74e-01 9.85e-01


Detailed Gene set reports


Neutrophil degranulation

Neutrophil degranulation
metric value
setSize 456
pMANOVA 1.26e-111
p.adjustMANOVA 1.72e-108
s.dist 0.77
s.low.CRP 0.491
s.high.CRP 0.593
p.low.CRP 9.83e-73
p.high.CRP 2.07e-105




Top 20 genes
Gene low CRP high CRP
S100A9 10110 10116
SIRPA 10106 10119
IDH1 10122 10092
CTSA 10083 10131
MCEMP1 10086 10124
S100A12 10088 10121
RNASE2 10073 10107
CR1 10079 10078
CD93 10035 10122
S100A8 10041 10093
CREG1 10046 10059
MGST1 10098 9993
BST1 10108 9972
TIMP2 9988 10081
SERPINB1 10061 9986
ATP6V0A1 9995 10010
PYGL 10071 9926
PGAM1 9980 9987
GCA 10102 9849
HP 9925 10000

Click HERE to show all gene set members

All member genes
low CRP high CRP
A1BG 5929 5909
ABCA13 9410 -170
ACAA1 6662 9280
ACLY -3163 7024
ACTR10 8589 7569
ACTR1B -10279 -5884
ACTR2 8743 7962
ADAM10 9314 9481
ADAM8 -5458 6863
ADGRE3 -5376 2276
ADGRE5 -10651 4158
ADGRG3 3363 8936
AGA -7643 -940
AGL -3370 -1431
AGPAT2 9161 10022
ALAD 8384 9011
ALDH3B1 8834 9423
ALDOA 9625 9857
ALDOC -3 -2424
ALOX5 9516 9496
AMPD3 9213 9215
ANO6 9199 8127
ANPEP 9881 9819
ANXA2 8647 9102
AOC1 6446 7328
AP1M1 -3219 8558
AP2A2 3196 9217
APAF1 9873 9119
APEH -8617 5030
APRT -2805 -663
ARG1 9021 8594
ARHGAP9 -1609 8482
ARL8A 6964 9003
ARMC8 8306 5850
ARPC5 9301 9174
ARSA -218 5556
ARSB 8124 8067
ASAH1 9274 8880
ATAD3B -7970 -8653
ATG7 9062 8455
ATP11A 8506 9066
ATP11B 1885 6335
ATP6AP2 9221 7743
ATP6V0A1 9995 10010
ATP6V0C 9348 9734
ATP6V1D 9600 9482
ATP8A1 -9269 -10981
ATP8B4 7888 7537
AZU1 9483 1924
B2M -4257 -4660
B4GALT1 -4177 7099
BIN2 -7555 7878
BPI 9613 4607
BRI3 9055 9716
BST1 10108 9972
BST2 -8159 -3534
C3 -11179 -10489
C3AR1 8924 8181
C5AR1 9359 9709
C6orf120 5882 7163
CAB39 9181 8435
CAMP 9421 -389
CAND1 3497 -7234
CANT1 7020 8333
CAP1 8192 8530
CAPN1 7094 9770
CAT 9793 9327
CCT2 1978 -8922
CCT8 8723 5878
CD14 9551 9658
CD177 9810 2861
CD300A -10110 3601
CD33 9714 7077
CD36 10064 9814
CD44 8303 9047
CD47 -9758 -11025
CD53 5300 8871
CD55 9326 9842
CD58 6098 7272
CD59 4075 5772
CD63 8797 10079
CD68 8809 9128
CD93 10035 10122
CDA 9766 9792
CDK13 -9826 -1367
CEACAM1 8749 7909
CEACAM3 4583 7056
CEACAM6 8933 1336
CEACAM8 9111 1929
CEP290 2753 -10189
CFD 2998 2390
CFP 6744 8615
CHI3L1 4876 -2511
CHIT1 8764 5022
CKAP4 10101 9674
CLEC12A 6739 3764
CLEC4C -11151 -7325
CLEC4D 10004 9296
CLEC5A 9544 8477
CMTM6 8818 8010
CNN2 2919 7385
COMMD3 1068 -670
COMMD9 8869 7706
COPB1 8213 7283
COTL1 7691 8602
CPNE1 -7895 1521
CPNE3 7732 5446
CPPED1 9258 8367
CR1 10079 10078
CRACR2A -10740 -2401
CREG1 10046 10059
CRISP3 9520 5095
CRISPLD2 9508 9755
CSNK2B 1222 5287
CST3 1960 3081
CSTB 4302 7960
CTSA 10083 10131
CTSB 9526 10083
CTSC -7528 5285
CTSD 9620 10120
CTSG 9156 1689
CTSH 6991 6545
CTSS 9854 7280
CTSZ 8972 9860
CXCL1 4484 5698
CXCR1 2112 7643
CXCR2 4038 6148
CYB5R3 8185 9788
CYBA -48 8901
CYBB 9900 8910
CYFIP1 9724 9912
CYSTM1 9061 9479
DBNL 5107 8904
DDOST 459 8249
DDX3X 8543 6111
DEFA1 9407 3685
DEFA4 9471 3488
DEGS1 6718 6254
DERA 9044 8799
DGAT1 3473 6135
DIAPH1 -9216 4270
DNAJC13 9339 8451
DNAJC3 9077 8882
DNAJC5 8400 9628
DNASE1L1 7462 9707
DOCK2 6433 8942
DOK3 9913 9988
DPP7 -4737 -1700
DSC1 2498 -9997
DSN1 -8825 -8996
DSP -2099 -1252
DYNC1H1 -8881 -2533
DYNC1LI1 7894 6997
DYNLL1 6026 6499
DYNLT1 1870 5508
EEF1A1 53 -4688
EEF2 -2498 2707
ELANE 9880 4888
ENPP4 -10919 -4181
EPX 4309 -6896
ERP44 8740 6170
FABP5 4135 6969
FAF2 2326 6842
FCAR 9865 9508
FCER1G 6595 9147
FCGR2A 9414 9249
FCGR3B 4203 4625
FCN1 9889 9103
FGL2 8307 -4026
FGR 6254 9666
FOLR3 7933 7989
FPR1 9606 9929
FPR2 9572 9728
FRK 23 486
FRMPD3 -11030 -7462
FTH1 3543 5337
FTL 8704 9324
FUCA1 8013 8533
FUCA2 9577 7885
GAA 8448 8356
GALNS 6719 8385
GCA 10102 9849
GDI2 8206 7892
GGH 5742 6109
GHDC 4753 4443
GLA 8923 9083
GLB1 9091 9091
GLIPR1 9841 6015
GM2A 9396 9808
GMFG 7620 8986
GNS 9627 10060
GOLGA7 4113 4351
GPI 3712 6865
GPR84 9267 9312
GRN 9760 9908
GSDMD -1632 4125
GSN 9281 9397
GSTP1 -3317 2661
GUSB 2374 9501
GYG1 9474 9547
HBB 10013 8750
HEBP2 8767 8822
HEXB 9386 9202
HGSNAT 4689 2250
HK3 9953 9940
HLA-A -5067 570
HLA-B -1559 1570
HLA-C -2829 2125
HLA-H -8161 452
HMGB1 3876 -968
HMOX2 -10770 -8356
HP 9925 10000
HPSE 9514 8535
HRNR -7455 -5209
HSP90AA1 5309 410
HSP90AB1 2247 -6319
HSPA1A 8217 8368
HSPA1B 5673 7177
HSPA6 2686 7632
HSPA8 -8286 -8908
HUWE1 -8883 -3494
HVCN1 7539 4235
IDH1 10122 10092
IGF2R -1133 9240
ILF2 -2090 951
IMPDH1 9819 9891
IMPDH2 -3563 -10154
IQGAP1 7310 9366
IQGAP2 6198 7948
IST1 260 7296
ITGAL -10958 -4334
ITGAM 9846 10065
ITGAV 7467 6188
ITGAX 3250 8762
ITGB2 8042 10007
JUP -4305 -4960
KCMF1 7123 8439
KCNAB2 -9549 5424
KPNB1 -1223 3575
KRT1 6823 4687
LAIR1 -466 8850
LAMP1 1737 9127
LAMP2 9608 8999
LAMTOR1 9915 9919
LAMTOR2 3802 9208
LAMTOR3 9012 7104
LCN2 9447 6200
LGALS3 9602 8710
LILRB2 6423 9453
LILRB3 8958 9554
LPCAT1 -10952 2487
LRG1 6784 9458
LRRC7 -623 -1369
LTA4H 9933 9541
LTF 9374 3485
LYZ 9774 5791
MAGT1 574 3711
MAN2B1 7665 7139
MANBA 9330 6620
MAPK1 1052 9260
MAPK14 9907 9606
MCEMP1 10086 10124
METTL7A 8352 6827
MGAM 8661 9588
MGST1 10098 9993
MIF -4739 -1332
MLEC 1226 3680
MME -1752 1424
MMP25 6740 9386
MMP8 9818 1522
MMP9 9225 9700
MNDA 10027 9394
MOSPD2 9799 8045
MPO 9985 4616
MS4A3 8707 -2464
MVP 4779 8093
NAPRT 6522 8450
NBEAL2 2363 8445
NCKAP1L 3966 9566
NCSTN 9503 9869
NDUFC2 1951 7994
NEU1 9336 9571
NFAM1 9370 9863
NFKB1 7857 6377
NHLRC3 4253 1252
NIT2 -7855 -11064
NME2 2395 3054
NPC2 6632 5511
NRAS 7321 4878
OLFM4 9728 7424
OLR1 8411 -2056
ORM1 8665 8363
ORM2 -4938 149
ORMDL3 -9307 -7231
OSCAR 9651 9561
OSTF1 6441 8058
P2RX1 7223 9888
PA2G4 -997 -1395
PADI2 9767 9703
PAFAH1B2 7693 7761
PDAP1 -4620 8599
PDXK 9135 9342
PECAM1 8136 8308
PFKL -4964 514
PGAM1 9980 9987
PGLYRP1 8816 7750
PGM1 -2421 7047
PGM2 9878 9866
PGRMC1 9328 7693
PIGR 1807 -551
PKM 9904 9954
PLAC8 6624 9383
PLAU 1698 5458
PLAUR 8428 9009
PLD1 9826 9945
PLEKHO2 6392 9014
PNP 9167 8393
PPBP 7528 6376
PPIA -7248 -2108
PPIE -5515 -9064
PRCP 8403 8843
PRDX4 1893 563
PRDX6 9609 8969
PRKCD 9393 9642
PRTN3 9645 4535
PSAP 7519 7770
PSEN1 7889 8878
PSMA2 5830 5666
PSMA5 -2119 -3983
PSMB1 3915 4224
PSMB7 8034 9051
PSMC2 -2524 4517
PSMC3 -4971 4984
PSMD1 7679 7587
PSMD11 6914 6824
PSMD12 9011 5710
PSMD13 3157 7205
PSMD14 2891 3041
PSMD2 4352 8396
PSMD3 -2243 6367
PSMD6 8841 8304
PSMD7 6534 6147
PTAFR 9791 9983
PTGES2 -6197 -3780
PTPN6 -691 7862
PTPRB -9635 -4262
PTPRC -3326 4087
PTPRJ 4613 9148
PTPRN2 3436 5350
PTX3 8865 4044
PYCARD 8329 9425
PYGB -5192 3500
PYGL 10071 9926
QPCT 9809 9852
QSOX1 9451 10048
RAB10 9303 9477
RAB14 8215 7014
RAB18 9425 7287
RAB24 2905 6201
RAB27A 9164 8675
RAB31 9956 9895
RAB37 -11095 -6455
RAB3A 7816 8757
RAB3D 9596 9946
RAB44 4572 -693
RAB4B -7808 7089
RAB5B 3295 7820
RAB5C 7846 9422
RAB6A 8487 8616
RAB7A 8897 9367
RAB9B -5682 -4620
RAC1 9052 9614
RAP1A 8688 6973
RAP1B -2703 4941
RAP2B -6678 3725
RAP2C 426 5484
RETN 9209 9105
RHOA 8351 8888
RHOF -11160 -10418
RHOG 7549 9255
RNASE2 10073 10107
RNASE3 9238 6921
RNASET2 5158 6487
ROCK1 8315 7930
S100A11 9254 9466
S100A12 10088 10121
S100A8 10041 10093
S100A9 10110 10116
S100P 5927 9300
SCAMP1 7532 -1630
SDCBP 9944 9687
SELL 9694 9159
SERPINA1 9571 9817
SERPINB1 10061 9986
SERPINB10 9936 8636
SERPINB6 3579 7946
SIGLEC14 8633 4157
SIGLEC5 8330 8707
SIGLEC9 9722 10062
SIRPA 10106 10119
SIRPB1 7638 9107
SLC11A1 9129 9947
SLC15A4 -8597 6968
SLC27A2 6501 -6385
SLC2A3 9614 9612
SLC2A5 7731 -721
SLC44A2 -8609 5338
SLCO4C1 -10306 5158
SLPI 9291 3565
SNAP23 9586 8642
SNAP29 -1741 8902
SPTAN1 -10174 -8889
SRP14 4915 7324
STBD1 3893 5802
STING1 6507 4536
STK10 -10951 4288
STK11IP -6497 6947
STOM 1151 7088
SURF4 3781 8016
SVIP 4431 1345
SYNGR1 -8211 -736
TARM1 8354 4978
TBC1D10C -10716 -9378
TCIRG1 1085 9058
TCN1 8724 3700
TICAM2 9182 4768
TIMP2 9988 10081
TLR2 9930 9118
TMBIM1 6724 9228
TMC6 -8623 -9689
TMEM179B 821 1646
TMEM30A 9288 7807
TMEM63A -1958 -10069
TNFAIP6 8375 9294
TNFRSF1B 1146 8282
TOLLIP 8447 9165
TOM1 9299 9952
TRAPPC1 5277 9110
TRPM2 9480 9785
TSPAN14 -706 8468
TUBB -9096 -626
TUBB4B 6246 7789
TXNDC5 6834 -3539
TYROBP 6139 8494
UBR4 -6416 1703
UNC13D -1509 9298
VAMP8 2890 6767
VAPA 9732 9322
VAT1 9437 10049
VCL 7488 7955
VCP 3600 7754
VNN1 9174 9668
VPS35L 5526 7038
XRCC5 6475 5318
XRCC6 -2658 -1055
YPEL5 7863 6331



Innate Immune System

Innate Immune System
metric value
setSize 963
pMANOVA 6.13e-91
p.adjustMANOVA 4.18e-88
s.dist 0.487
s.low.CRP 0.319
s.high.CRP 0.368
p.low.CRP 1.7e-63
p.high.CRP 7.54e-84




Top 20 genes
Gene low CRP high CRP
S100A9 10110 10116
SIRPA 10106 10119
WASF1 10091 10132
IDH1 10122 10092
CTSA 10083 10131
MCEMP1 10086 10124
S100A12 10088 10121
RNASE2 10073 10107
CR1 10079 10078
CD93 10035 10122
S100A8 10041 10093
CREG1 10046 10059
MGST1 10098 9993
BST1 10108 9972
TIMP2 9988 10081
SERPINB1 10061 9986
CCR2 10062 9973
ATP6V0A1 9995 10010
PYGL 10071 9926
PGAM1 9980 9987

Click HERE to show all gene set members

All member genes
low CRP high CRP
A1BG 5929 5909
AAMP -5066 55
ABCA13 9410 -170
ABI1 6692 7709
ABI2 -7512 -9823
ABL1 -6354 4467
ACAA1 6662 9280
ACLY -3163 7024
ACTB 9310 9714
ACTG1 7674 9499
ACTR10 8589 7569
ACTR1B -10279 -5884
ACTR2 8743 7962
ACTR3 8622 7832
ADAM10 9314 9481
ADAM8 -5458 6863
ADGRE3 -5376 2276
ADGRE5 -10651 4158
ADGRG3 3363 8936
AGA -7643 -940
AGER -1839 3181
AGL -3370 -1431
AGPAT2 9161 10022
AHCYL1 6114 7566
AIM2 4180 -3050
ALAD 8384 9011
ALDH3B1 8834 9423
ALDOA 9625 9857
ALDOC -3 -2424
ALOX5 9516 9496
ALPK1 9935 8739
AMPD3 9213 9215
ANO6 9199 8127
ANPEP 9881 9819
ANXA2 8647 9102
AOC1 6446 7328
AP1M1 -3219 8558
AP2A2 3196 9217
APAF1 9873 9119
APEH -8617 5030
APP 9951 9504
APRT -2805 -663
ARG1 9021 8594
ARHGAP9 -1609 8482
ARL8A 6964 9003
ARMC8 8306 5850
ARPC1A 8875 9605
ARPC1B 9259 10026
ARPC2 5327 8212
ARPC3 8430 8946
ARPC4 4637 8915
ARPC5 9301 9174
ARSA -218 5556
ARSB 8124 8067
ASAH1 9274 8880
ATAD3B -7970 -8653
ATF1 7833 5463
ATF2 7002 164
ATG12 6218 -2966
ATG5 5545 637
ATG7 9062 8455
ATOX1 -3567 6465
ATP11A 8506 9066
ATP11B 1885 6335
ATP6AP2 9221 7743
ATP6V0A1 9995 10010
ATP6V0A2 -10623 -10379
ATP6V0B 8163 9396
ATP6V0C 9348 9734
ATP6V0D1 9444 9942
ATP6V0E1 8171 9289
ATP6V0E2 -8802 -11036
ATP6V1A 9857 9880
ATP6V1B2 9738 9281
ATP6V1C1 9888 8528
ATP6V1C2 2655 -3376
ATP6V1D 9600 9482
ATP6V1E1 8095 8397
ATP6V1E2 8322 4968
ATP6V1F 3461 6917
ATP6V1G1 5204 4277
ATP6V1G2 -4714 -10140
ATP6V1H 7942 8571
ATP7A -5957 3433
ATP8A1 -9269 -10981
ATP8B4 7888 7537
AZU1 9483 1924
B2M -4257 -4660
B4GALT1 -4177 7099
BAIAP2 2620 -682
BCL10 6467 6003
BCL2 6148 -7816
BCL2L1 9743 8443
BIN2 -7555 7878
BIRC2 8079 3449
BIRC3 -2270 -11079
BPI 9613 4607
BRI3 9055 9716
BRK1 5522 8298
BST1 10108 9972
BST2 -8159 -3534
BTK 7623 7870
BTRC -6845 -441
C1QA -49 7890
C1QB 6746 8930
C1QC 7805 9340
C1R -10393 -4020
C1S -6159 552
C2 6634 2959
C3 -11179 -10489
C3AR1 8924 8181
C4A 5060 4740
C4B 6359 2884
C4BPB 3624 -4862
C5 7727 2354
C5AR1 9359 9709
C5AR2 8198 8666
C6orf120 5882 7163
C8G -10839 -8035
CAB39 9181 8435
CALM1 -6645 1321
CAMP 9421 -389
CAND1 3497 -7234
CANT1 7020 8333
CAP1 8192 8530
CAPN1 7094 9770
CAPZA1 8666 8511
CAPZA2 9698 8474
CARD11 -11093 -10157
CARD9 7781 6520
CASP1 8236 2513
CASP10 -2054 -1105
CASP2 -2223 235
CASP4 5719 6185
CASP8 -10359 -8523
CASP9 5303 9133
CAT 9793 9327
CCR2 10062 9973
CCR6 -2172 -9131
CCT2 1978 -8922
CCT8 8723 5878
CD14 9551 9658
CD177 9810 2861
CD180 -749 281
CD19 -2992 -2929
CD209 -5894 -8203
CD247 -11271 -10327
CD300A -10110 3601
CD300E 8420 6279
CD300LB 9081 6385
CD33 9714 7077
CD36 10064 9814
CD3G -9054 -10504
CD4 3147 -5743
CD44 8303 9047
CD46 8744 5145
CD47 -9758 -11025
CD53 5300 8871
CD55 9326 9842
CD58 6098 7272
CD59 4075 5772
CD63 8797 10079
CD68 8809 9128
CD81 -10685 -3573
CD93 10035 10122
CDA 9766 9792
CDC34 8212 9329
CDC42 8498 7640
CDK13 -9826 -1367
CEACAM1 8749 7909
CEACAM3 4583 7056
CEACAM6 8933 1336
CEACAM8 9111 1929
CEP290 2753 -10189
CFB -3014 -2968
CFD 2998 2390
CFH -3147 -6338
CFL1 5851 9242
CFP 6744 8615
CGAS 7673 6354
CHI3L1 4876 -2511
CHIT1 8764 5022
CHUK 9198 7663
CKAP4 10101 9674
CLEC10A -5519 -3549
CLEC12A 6739 3764
CLEC4A 9522 7775
CLEC4C -11151 -7325
CLEC4D 10004 9296
CLEC4E 8952 8732
CLEC5A 9544 8477
CLEC6A 7472 6730
CLEC7A 9123 3695
CLU 9512 10102
CMTM6 8818 8010
CNN2 2919 7385
CNPY3 7458 8402
COMMD3 1068 -670
COMMD9 8869 7706
COPB1 8213 7283
COTL1 7691 8602
CPN2 8266 1159
CPNE1 -7895 1521
CPNE3 7732 5446
CPPED1 9258 8367
CR1 10079 10078
CR2 -1342 -3900
CRACR2A -10740 -2401
CRCP 910 6330
CREB1 4878 -3476
CREBBP -4951 6023
CREG1 10046 10059
CRISP3 9520 5095
CRISPLD2 9508 9755
CRK 9657 9429
CSNK2B 1222 5287
CST3 1960 3081
CSTB 4302 7960
CTNNB1 3201 7613
CTSA 10083 10131
CTSB 9526 10083
CTSC -7528 5285
CTSD 9620 10120
CTSG 9156 1689
CTSH 6991 6545
CTSK 7647 4123
CTSL -5538 5895
CTSS 9854 7280
CTSV -1271 -2930
CTSZ 8972 9860
CUL1 -2085 -10951
CXCL1 4484 5698
CXCR1 2112 7643
CXCR2 4038 6148
CYB5R3 8185 9788
CYBA -48 8901
CYBB 9900 8910
CYFIP1 9724 9912
CYFIP2 -10558 -4935
CYLD 2995 -11046
CYSTM1 9061 9479
DBNL 5107 8904
DDOST 459 8249
DDX3X 8543 6111
DDX41 -566 5152
DDX58 -10158 -10278
DEFA1 9407 3685
DEFA3 8772 3736
DEFA4 9471 3488
DEGS1 6718 6254
DERA 9044 8799
DGAT1 3473 6135
DHX36 562 -4982
DHX58 -9970 -10297
DHX9 2911 1989
DIAPH1 -9216 4270
DNAJC13 9339 8451
DNAJC3 9077 8882
DNAJC5 8400 9628
DNASE1L1 7462 9707
DNM1 6883 3239
DNM2 -6816 8202
DNM3 7927 7198
DOCK1 6941 8390
DOCK2 6433 8942
DOK3 9913 9988
DPP7 -4737 -1700
DSC1 2498 -9997
DSN1 -8825 -8996
DSP -2099 -1252
DTX4 1850 7305
DUSP3 9937 9647
DUSP4 -6630 -4192
DUSP6 7994 2589
DUSP7 -4748 387
DYNC1H1 -8881 -2533
DYNC1LI1 7894 6997
DYNLL1 6026 6499
DYNLT1 1870 5508
ECSIT 4110 5590
EEA1 8100 3526
EEF1A1 53 -4688
EEF2 -2498 2707
ELANE 9880 4888
ELK1 -355 3195
ELMO1 4243 7282
ELMO2 -9506 6592
ENPP4 -10919 -4181
EP300 4311 7552
EPPIN 3878 1579
EPX 4309 -6896
ERP44 8740 6170
FABP5 4135 6969
FADD -3611 7477
FAF2 2326 6842
FBXW11 4585 7364
FCAR 9865 9508
FCER1A -10921 -10940
FCER1G 6595 9147
FCGR1A 9965 9575
FCGR2A 9414 9249
FCGR3A -11272 -4672
FCGR3B 4203 4625
FCN1 9889 9103
FGL2 8307 -4026
FGR 6254 9666
FOLR3 7933 7989
FOS 6663 6569
FPR1 9606 9929
FPR2 9572 9728
FRK 23 486
FRMPD3 -11030 -7462
FTH1 3543 5337
FTL 8704 9324
FUCA1 8013 8533
FUCA2 9577 7885
FYN -10878 -6729
GAA 8448 8356
GAB2 7546 9347
GALNS 6719 8385
GCA 10102 9849
GDI2 8206 7892
GGH 5742 6109
GHDC 4753 4443
GLA 8923 9083
GLB1 9091 9091
GLIPR1 9841 6015
GM2A 9396 9808
GMFG 7620 8986
GNLY -11065 -6613
GNS 9627 10060
GOLGA7 4113 4351
GPI 3712 6865
GPR84 9267 9312
GRAP2 5425 4991
GRB2 9631 9985
GRN 9760 9908
GSDMD -1632 4125
GSN 9281 9397
GSTP1 -3317 2661
GUSB 2374 9501
GYG1 9474 9547
GZMM -11118 -8768
HBB 10013 8750
HCK 9286 9494
HEBP2 8767 8822
HERC5 -10767 -10994
HEXB 9386 9202
HGSNAT 4689 2250
HK3 9953 9940
HLA-A -5067 570
HLA-B -1559 1570
HLA-C -2829 2125
HLA-E -10409 2003
HLA-H -8161 452
HMGB1 3876 -968
HMOX2 -10770 -8356
HP 9925 10000
HPSE 9514 8535
HRAS -2248 -1932
HRNR -7455 -5209
HSP90AA1 5309 410
HSP90AB1 2247 -6319
HSP90B1 7042 372
HSPA1A 8217 8368
HSPA1B 5673 7177
HSPA6 2686 7632
HSPA8 -8286 -8908
HTN1 -1993 -3136
HUWE1 -8883 -3494
HVCN1 7539 4235
ICAM2 -10403 -10529
ICAM3 6434 8725
IDH1 10122 10092
IFI16 5821 -734
IFIH1 -6483 -10093
IGF2R -1133 9240
IGHE -498 -5753
IGHG1 -1124 -7111
IGHG2 -5587 -6004
IGHG3 -507 -4089
IGHG4 -4038 -5940
IGHV1-2 5956 -3146
IGHV1-46 3766 -2976
IGHV1-69 2354 -2328
IGHV2-5 4451 -1972
IGHV2-70 -3315 -2159
IGHV3-11 3518 -4591
IGHV3-13 799 -2451
IGHV3-23 6032 -5092
IGHV3-30 2500 -5193
IGHV3-33 98 -4138
IGHV3-48 3183 -4340
IGHV3-53 3131 -1786
IGHV3-7 4185 -3630
IGHV4-34 1144 -4007
IGHV4-39 3786 -6542
IGHV4-59 4532 -5870
IGKC 2773 -6437
IGKV1-12 725 -6674
IGKV1-16 6217 -5451
IGKV1-17 -241 -2794
IGKV1-33 5955 -6384
IGKV1-5 6127 -5162
IGKV1D-39 5018 -2677
IGKV2-28 1440 -6662
IGKV2-30 5205 -5349
IGKV2D-28 -7224 -2947
IGKV3-11 5548 -7167
IGKV3-15 3174 -4687
IGKV3-20 3704 -5021
IGKV3D-20 -1830 -4618
IGKV4-1 2812 -4988
IGKV5-2 5226 -2682
IGLC1 -2813 -6176
IGLC2 -258 -6539
IGLC3 -2958 -4378
IGLC7 -3403 -4490
IGLV1-36 3522 -5030
IGLV1-40 163 -5497
IGLV1-44 4742 -5791
IGLV1-47 231 -6633
IGLV1-51 1708 -6601
IGLV10-54 -5422 316
IGLV2-11 870 -3205
IGLV2-14 -5127 -8197
IGLV2-18 2015 -2963
IGLV2-23 2029 -4201
IGLV2-8 4818 -5256
IGLV3-1 -96 -5140
IGLV3-12 -7299 -6816
IGLV3-19 4006 -5611
IGLV3-21 -975 -6062
IGLV3-25 -942 -5485
IGLV3-27 -5365 -4834
IGLV4-69 1344 -2261
IGLV5-45 4194 -7364
IGLV6-57 1834 -5837
IGLV7-43 4854 -2823
IGLV7-46 2445 -3619
IGLV8-61 -3989 -5208
IKBKB -5276 -2118
IKBKE 387 6793
IKBKG -3058 7903
IL1B 7489 3385
ILF2 -2090 951
IMPDH1 9819 9891
IMPDH2 -3563 -10154
IQGAP1 7310 9366
IQGAP2 6198 7948
IRAK1 2444 7601
IRAK2 -11058 -2404
IRAK3 9660 9553
IRF3 -6904 -7151
IRF7 -8896 -5369
ISG15 -10543 -10488
IST1 260 7296
ITCH -2889 3792
ITGAL -10958 -4334
ITGAM 9846 10065
ITGAV 7467 6188
ITGAX 3250 8762
ITGB2 8042 10007
ITK -7038 -10924
ITLN1 -9302 -3066
ITPR1 -5546 -5368
ITPR2 6833 6418
ITPR3 -8438 -9066
JUN 2838 4810
JUP -4305 -4960
KCMF1 7123 8439
KCNAB2 -9549 5424
KIR2DS4 -10465 -3358
KLRC2 -10041 -6047
KLRD1 -11180 -7991
KLRK1 -11056 -10731
KPNB1 -1223 3575
KRAS 3789 4070
KRT1 6823 4687
LAIR1 -466 8850
LAMP1 1737 9127
LAMP2 9608 8999
LAMTOR1 9915 9919
LAMTOR2 3802 9208
LAMTOR3 9012 7104
LAT -9843 -10628
LAT2 8582 9705
LCK -10358 -10719
LCN2 9447 6200
LCP2 -2426 872
LEAP2 -3994 -3354
LGALS3 9602 8710
LGMN -3548 -2820
LILRB2 6423 9453
LILRB3 8958 9554
LIMK1 -2747 6617
LPCAT1 -10952 2487
LPO 8757 5426
LRG1 6784 9458
LRRC7 -623 -1369
LRRFIP1 6242 6811
LTA4H 9933 9541
LTF 9374 3485
LY86 9457 6684
LY96 9529 8995
LYN 7575 8379
LYZ 9774 5791
MAGT1 574 3711
MALT1 -1301 -11074
MAN2B1 7665 7139
MANBA 9330 6620
MAP2K1 9163 9879
MAP2K3 8978 9308
MAP2K4 6895 7431
MAP2K6 9435 9577
MAP2K7 -2754 4813
MAP3K1 5466 5938
MAP3K14 -10222 -9826
MAP3K7 1546 4274
MAP3K8 -7139 8928
MAPK1 1052 9260
MAPK10 6734 3872
MAPK11 7257 1843
MAPK12 1925 -1837
MAPK13 -8511 5595
MAPK14 9907 9606
MAPK3 8931 9626
MAPK7 -10125 5069
MAPK8 -1061 -9914
MAPK9 -6530 -1870
MAPKAPK2 -10572 6892
MAPKAPK3 7493 9250
MASP2 2089 -6883
MAVS 6465 9067
MCEMP1 10086 10124
MEF2A 9000 8162
MEF2C 6943 -2868
MEFV 9094 9246
METTL7A 8352 6827
MGAM 8661 9588
MGST1 10098 9993
MIF -4739 -1332
MLEC 1226 3680
MME -1752 1424
MMP25 6740 9386
MMP8 9818 1522
MMP9 9225 9700
MNDA 10027 9394
MOSPD2 9799 8045
MPO 9985 4616
MRE11 -4492 -8162
MS4A2 -5654 -10490
MS4A3 8707 -2464
MUC1 8159 7011
MUC12 -8506 -9690
MUC16 377 -5584
MUC20 -2625 -6328
MUC4 643 -4710
MUC5B -8416 -622
MUC6 -3460 -1745
MUCL1 -1878 -1414
MVP 4779 8093
MYD88 8651 8344
MYH9 1879 8348
MYO10 9409 9473
MYO1C 6395 2929
MYO5A 6789 7727
MYO9B 513 8592
NAPRT 6522 8450
NBEAL2 2363 8445
NCF1 8576 7083
NCF2 9748 9694
NCF4 9697 9856
NCK1 -9250 -9113
NCKAP1 6871 8168
NCKAP1L 3966 9566
NCKIPSD 957 1858
NCSTN 9503 9869
NDUFC2 1951 7994
NEU1 9336 9571
NF2 -9157 -819
NFAM1 9370 9863
NFATC1 -9648 -4795
NFATC2 -11185 -10445
NFATC3 -10822 -10053
NFKB1 7857 6377
NFKB2 3069 -1167
NFKBIA 6855 7374
NFKBIB -9679 5479
NHLRC3 4253 1252
NIT2 -7855 -11064
NKIRAS1 2619 689
NKIRAS2 9581 9936
NLRC3 -11019 -10784
NLRC4 9962 10003
NLRC5 -8425 -8806
NLRP1 -1438 -6109
NLRP3 9708 8944
NLRX1 3934 9137
NME2 2395 3054
NOD1 -10930 -10348
NOD2 9408 8613
NOS1 4727 -183
NOS3 5934 -5046
NPC2 6632 5511
NRAS 7321 4878
OLFM4 9728 7424
OLR1 8411 -2056
ORM1 8665 8363
ORM2 -4938 149
ORMDL3 -9307 -7231
OSCAR 9651 9561
OSTF1 6441 8058
OTUD5 -9093 2293
P2RX1 7223 9888
P2RX7 5741 3066
PA2G4 -997 -1395
PADI2 9767 9703
PAFAH1B2 7693 7761
PAK1 9711 7682
PAK2 9019 8433
PAK3 -1134 -4249
PANX1 6263 6597
PCBP2 6380 5411
PDAP1 -4620 8599
PDPK1 2392 7816
PDXK 9135 9342
PDZD11 -9036 -585
PECAM1 8136 8308
PELI1 9064 5690
PELI2 9242 9060
PELI3 5708 8764
PFKL -4964 514
PGAM1 9980 9987
PGLYRP1 8816 7750
PGLYRP2 -9721 3276
PGM1 -2421 7047
PGM2 9878 9866
PGRMC1 9328 7693
PI3 8550 -782
PIGR 1807 -551
PIK3C3 6605 573
PIK3CA 6889 4182
PIK3CB 9838 9248
PIK3R1 -7197 -8942
PIK3R2 2459 5820
PIK3R4 -267 -2209
PIN1 -9660 3728
PKM 9904 9954
PLA2G6 -10753 -10993
PLAC8 6624 9383
PLAU 1698 5458
PLAUR 8428 9009
PLCG1 -6360 -11043
PLCG2 -4618 6826
PLD1 9826 9945
PLD2 7087 7779
PLD3 8640 7098
PLD4 -11266 -11216
PLEKHO2 6392 9014
PLPP5 -4861 -6194
PNP 9167 8393
POLR1C -5223 -10095
POLR1D 8331 5916
POLR2E 6766 8343
POLR2F -2307 6746
POLR2H 653 -2264
POLR2K 1881 -1885
POLR2L 126 7246
POLR3A -8082 -1838
POLR3B -7085 -3891
POLR3C -238 -5145
POLR3D -9064 -10412
POLR3E -9777 -9560
POLR3F 3481 -7424
POLR3G -3249 -4541
POLR3GL -9923 -272
POLR3H -7488 -8017
POLR3K -815 -1133
PPBP 7528 6376
PPIA -7248 -2108
PPIE -5515 -9064
PPP2CA 8810 8328
PPP2CB 8482 7631
PPP2R1A -3087 6994
PPP2R1B 2503 437
PPP2R5D -6508 4985
PPP3CA 6208 7300
PPP3CB 8057 6833
PPP3R1 8998 8570
PRCP 8403 8843
PRDX4 1893 563
PRDX6 9609 8969
PRKACA 9885 10068
PRKACB -9852 -10936
PRKCD 9393 9642
PRKCE -10383 -2720
PRKCQ -10709 -10890
PRKCSH -3697 7582
PRKDC -8444 -7899
PROS1 9065 7937
PRTN3 9645 4535
PSAP 7519 7770
PSEN1 7889 8878
PSMA1 8278 7406
PSMA2 5830 5666
PSMA3 4646 -7621
PSMA4 3950 -1036
PSMA5 -2119 -3983
PSMA6 6893 5865
PSMA7 3550 8554
PSMB1 3915 4224
PSMB10 -7878 -1272
PSMB2 2664 4928
PSMB3 4971 8382
PSMB4 -3175 4911
PSMB5 6561 9138
PSMB6 1312 8784
PSMB7 8034 9051
PSMB8 -4481 75
PSMB9 -9105 -10433
PSMC1 6759 7782
PSMC2 -2524 4517
PSMC3 -4971 4984
PSMC4 -10757 -336
PSMC5 -3424 2764
PSMC6 8812 6000
PSMD1 7679 7587
PSMD10 2067 2450
PSMD11 6914 6824
PSMD12 9011 5710
PSMD13 3157 7205
PSMD14 2891 3041
PSMD2 4352 8396
PSMD3 -2243 6367
PSMD4 6858 9449
PSMD5 2770 4781
PSMD6 8841 8304
PSMD7 6534 6147
PSMD8 739 7117
PSMD9 3580 9001
PSME1 -7256 -7913
PSME2 -5548 -10355
PSME3 9120 8239
PSME4 -5205 -3127
PSMF1 6709 6770
PSTPIP1 4146 9452
PTAFR 9791 9983
PTGES2 -6197 -3780
PTK2 7786 3481
PTPN11 4691 6614
PTPN4 -10946 -10632
PTPN6 -691 7862
PTPRB -9635 -4262
PTPRC -3326 4087
PTPRJ 4613 9148
PTPRN2 3436 5350
PTX3 8865 4044
PYCARD 8329 9425
PYGB -5192 3500
PYGL 10071 9926
QPCT 9809 9852
QSOX1 9451 10048
RAB10 9303 9477
RAB14 8215 7014
RAB18 9425 7287
RAB24 2905 6201
RAB27A 9164 8675
RAB31 9956 9895
RAB37 -11095 -6455
RAB3A 7816 8757
RAB3D 9596 9946
RAB44 4572 -693
RAB4B -7808 7089
RAB5B 3295 7820
RAB5C 7846 9422
RAB6A 8487 8616
RAB7A 8897 9367
RAB9B -5682 -4620
RAC1 9052 9614
RAC2 -7677 6828
RAF1 8477 8327
RAP1A 8688 6973
RAP1B -2703 4941
RAP2B -6678 3725
RAP2C 426 5484
RASGRP1 -9849 -11029
RASGRP2 -7479 -7190
RASGRP4 9926 9901
RBSN -7312 339
RELA -7305 2739
RELB 3146 4566
RETN 9209 9105
RHOA 8351 8888
RHOF -11160 -10418
RHOG 7549 9255
RIPK1 -10879 -4699
RIPK2 1665 2297
RIPK3 -5133 7348
RNASE2 10073 10107
RNASE3 9238 6921
RNASE6 8782 6121
RNASET2 5158 6487
RNF125 -8706 -9750
RNF135 8493 9341
RNF216 -8194 -8556
ROCK1 8315 7930
RPS27A -3555 -7070
RPS6KA1 -105 9153
RPS6KA2 -5428 3882
RPS6KA3 2859 3437
RPS6KA5 -3980 -11177
S100A1 -7792 -5913
S100A11 9254 9466
S100A12 10088 10121
S100A8 10041 10093
S100A9 10110 10116
S100B -8212 -1271
S100P 5927 9300
SARM1 -10456 -10950
SCAMP1 7532 -1630
SDCBP 9944 9687
SELL 9694 9159
SEM1 993 5942
SERPINA1 9571 9817
SERPINB1 10061 9986
SERPINB10 9936 8636
SERPINB6 3579 7946
SERPING1 -6329 -10968
SHC1 -3416 5815
SIGIRR -9900 -8613
SIGLEC14 8633 4157
SIGLEC15 10015 9518
SIGLEC16 9890 9405
SIGLEC5 8330 8707
SIGLEC9 9722 10062
SIKE1 3865 -7566
SIRPA 10106 10119
SIRPB1 7638 9107
SKP1 8120 2700
SLC11A1 9129 9947
SLC15A4 -8597 6968
SLC27A2 6501 -6385
SLC2A3 9614 9612
SLC2A5 7731 -721
SLC44A2 -8609 5338
SLCO4C1 -10306 5158
SLPI 9291 3565
SNAP23 9586 8642
SNAP29 -1741 8902
SOCS1 -219 6051
SOS1 3534 -7412
SPTAN1 -10174 -8889
SRC -6857 -7229
SRP14 4915 7324
STAT6 2936 7753
STBD1 3893 5802
STING1 6507 4536
STK10 -10951 4288
STK11IP -6497 6947
STOM 1151 7088
SUGT1 7602 -482
SURF4 3781 8016
SVIP 4431 1345
SYK 9464 9848
SYNGR1 -8211 -736
TAB1 6623 5746
TAB2 9197 5726
TAB3 3912 3647
TANK 8959 7267
TARM1 8354 4978
TAX1BP1 7469 5996
TBC1D10C -10716 -9378
TBK1 5846 2973
TCIRG1 1085 9058
TCN1 8724 3700
TEC 8165 7953
TICAM1 6742 6552
TICAM2 9182 4768
TIFA 6543 4608
TIMP2 9988 10081
TIRAP 262 7730
TKFC 5127 5512
TLR1 9828 8868
TLR10 -122 -3607
TLR2 9930 9118
TLR3 -9935 -9836
TLR4 9494 9617
TLR5 9746 9721
TLR6 9634 9209
TLR7 8636 -4675
TLR8 9957 9871
TLR9 -10413 -138
TMBIM1 6724 9228
TMC6 -8623 -9689
TMEM179B 821 1646
TMEM30A 9288 7807
TMEM63A -1958 -10069
TNFAIP3 -10682 -6292
TNFAIP6 8375 9294
TNFRSF1B 1146 8282
TNIP2 -1490 7359
TOLLIP 8447 9165
TOM1 9299 9952
TRAF2 -9898 -9879
TRAF3 2694 -5265
TRAF6 -1767 2089
TRAPPC1 5277 9110
TREM1 5997 7651
TREX1 38 -316
TRIM21 1612 3394
TRIM25 8976 8487
TRIM32 -10314 -9171
TRIM56 -9020 -5699
TRPM2 9480 9785
TSPAN14 -706 8468
TUBB -9096 -626
TUBB4B 6246 7789
TXK -9905 -10778
TXN 8317 8729
TXNDC5 6834 -3539
TXNIP -9337 -6548
TYROBP 6139 8494
UBA3 9502 7030
UBA52 -1875 3023
UBA7 -5544 -5471
UBB 8251 6157
UBC -1915 5825
UBE2D1 9825 9491
UBE2D2 2673 5593
UBE2D3 9443 8783
UBE2K 8831 6196
UBE2L6 -8809 -9855
UBE2M 2776 9251
UBE2N 4087 2050
UBE2V1 6665 5995
UBR4 -6416 1703
UNC13D -1509 9298
UNC93B1 -1309 6224
VAMP8 2890 6767
VAPA 9732 9322
VAT1 9437 10049
VAV1 5553 8731
VAV2 -5033 -1339
VAV3 -6160 7203
VCL 7488 7955
VCP 3600 7754
VNN1 9174 9668
VPS35L 5526 7038
VRK3 -7245 5798
VTN -5291 730
WAS 8258 9323
WASF1 10091 10132
WASF2 7535 9576
WASF3 8142 7240
WASL 899 1391
WIPF1 -5700 3866
WIPF2 2722 7125
XRCC5 6475 5318
XRCC6 -2658 -1055
YES1 -11138 -8566
YPEL5 7863 6331
ZBP1 -11073 -10810



Immune System

Immune System
metric value
setSize 1885
pMANOVA 2.77e-52
p.adjustMANOVA 1.26e-49
s.dist 0.264
s.low.CRP 0.158
s.high.CRP 0.211
p.low.CRP 4.26e-30
p.high.CRP 4.62e-52




Top 20 genes
Gene low CRP high CRP
CSF2RA 10124 10140
S100A9 10110 10116
SIRPA 10106 10119
WASF1 10091 10132
IDH1 10122 10092
CTSA 10083 10131
MCEMP1 10086 10124
S100A12 10088 10121
RNASE2 10073 10107
CR1 10079 10078
CD93 10035 10122
S100A8 10041 10093
CREG1 10046 10059
VAMP7 10053 10044
MGST1 10098 9993
BST1 10108 9972
FBXO9 10081 9997
TIMP2 9988 10081
SERPINB1 10061 9986
CCR2 10062 9973

Click HERE to show all gene set members

All member genes
low CRP high CRP
A1BG 5929.0 5909.0
AAAS -8564.0 -4273.0
AAMP -5066.0 55.0
ABCA13 9410.0 -170.0
ABCE1 2287.0 -11103.0
ABHD17A -10947.0 -3689.0
ABHD17B -1880.0 2621.0
ABHD17C -8389.0 2084.0
ABI1 6692.0 7709.0
ABI2 -7512.0 -9823.0
ABL1 -6354.0 4467.0
ACAA1 6662.0 9280.0
ACLY -3163.0 7024.0
ACTB 9310.0 9714.0
ACTG1 7674.0 9499.0
ACTR10 8589.0 7569.0
ACTR1A -2833.0 8680.0
ACTR1B -10279.0 -5884.0
ACTR2 8743.0 7962.0
ACTR3 8622.0 7832.0
ADAM10 9314.0 9481.0
ADAM17 8058.0 9718.0
ADAM8 -5458.0 6863.0
ADAR -7526.0 -293.0
ADGRE3 -5376.0 2276.0
ADGRE5 -10651.0 4158.0
ADGRG3 3363.0 8936.0
AGA -7643.0 -940.0
AGER -1839.0 3181.0
AGL -3370.0 -1431.0
AGPAT2 9161.0 10022.0
AHCYL1 6114.0 7566.0
AIM2 4180.0 -3050.0
AIP -8999.0 2061.0
AKT1 -4794.0 6231.0
AKT2 -8391.0 5504.0
AKT3 -9616.0 -10833.0
ALAD 8384.0 9011.0
ALDH3B1 8834.0 9423.0
ALDOA 9625.0 9857.0
ALDOC -3.0 -2424.0
ALOX15 -6345.0 -9981.0
ALOX5 9516.0 9496.0
ALPK1 9935.0 8739.0
AMPD3 9213.0 9215.0
ANAPC1 -9718.0 -10978.0
ANAPC10 -4639.0 -2175.0
ANAPC11 3528.0 7783.0
ANAPC13 6822.0 1501.0
ANAPC2 -6824.0 -4561.0
ANAPC4 1210.0 -8491.0
ANAPC5 -8996.0 -8730.0
ANAPC7 -4282.0 -1578.0
ANGPT1 5647.0 1529.0
ANO6 9199.0 8127.0
ANPEP 9881.0 9819.0
ANXA1 8162.0 8222.0
ANXA2 8647.0 9102.0
AOC1 6446.0 7328.0
AP1B1 8214.0 9804.0
AP1G1 -1796.0 5288.0
AP1M1 -3219.0 8558.0
AP1M2 4764.0 1487.0
AP1S1 9235.0 9982.0
AP1S2 6862.0 -6065.0
AP1S3 -5309.0 -4187.0
AP2A1 -3194.0 9104.0
AP2A2 3196.0 9217.0
AP2B1 -9145.0 2444.0
AP2M1 7742.0 9334.0
AP2S1 7422.0 8877.0
APAF1 9873.0 9119.0
APBB1IP 9427.0 9201.0
APEH -8617.0 5030.0
APP 9951.0 9504.0
APRT -2805.0 -663.0
ARAF -5280.0 5379.0
AREG 4465.0 7165.0
AREL1 -2744.0 8240.0
ARF1 8465.0 9910.0
ARG1 9021.0 8594.0
ARHGAP9 -1609.0 8482.0
ARIH1 -1725.0 848.0
ARIH2 -10965.0 -8339.0
ARL2 -5078.0 2617.0
ARL8A 6964.0 9003.0
ARMC8 8306.0 5850.0
ARPC1A 8875.0 9605.0
ARPC1B 9259.0 10026.0
ARPC2 5327.0 8212.0
ARPC3 8430.0 8946.0
ARPC4 4637.0 8915.0
ARPC5 9301.0 9174.0
ARRB1 -4581.0 4541.0
ARRB2 7827.0 9274.0
ARSA -218.0 5556.0
ARSB 8124.0 8067.0
ASAH1 9274.0 8880.0
ASB1 -7632.0 6070.0
ASB13 3848.0 3880.0
ASB14 4303.0 -4544.0
ASB16 -8746.0 -2220.0
ASB2 -10926.0 -8940.0
ASB3 4105.0 1485.0
ASB4 -5055.0 -4525.0
ASB6 -7877.0 2463.0
ASB7 7450.0 6094.0
ASB8 823.0 6079.0
ASB9 4472.0 -207.0
ATAD3B -7970.0 -8653.0
ATF1 7833.0 5463.0
ATF2 7002.0 164.0
ATG12 6218.0 -2966.0
ATG5 5545.0 637.0
ATG7 9062.0 8455.0
ATOX1 -3567.0 6465.0
ATP11A 8506.0 9066.0
ATP11B 1885.0 6335.0
ATP6AP2 9221.0 7743.0
ATP6V0A1 9995.0 10010.0
ATP6V0A2 -10623.0 -10379.0
ATP6V0B 8163.0 9396.0
ATP6V0C 9348.0 9734.0
ATP6V0D1 9444.0 9942.0
ATP6V0E1 8171.0 9289.0
ATP6V0E2 -8802.0 -11036.0
ATP6V1A 9857.0 9880.0
ATP6V1B2 9738.0 9281.0
ATP6V1C1 9888.0 8528.0
ATP6V1C2 2655.0 -3376.0
ATP6V1D 9600.0 9482.0
ATP6V1E1 8095.0 8397.0
ATP6V1E2 8322.0 4968.0
ATP6V1F 3461.0 6917.0
ATP6V1G1 5204.0 4277.0
ATP6V1G2 -4714.0 -10140.0
ATP6V1H 7942.0 8571.0
ATP7A -5957.0 3433.0
ATP8A1 -9269.0 -10981.0
ATP8B4 7888.0 7537.0
AZU1 9483.0 1924.0
B2M -4257.0 -4660.0
B4GALT1 -4177.0 7099.0
BAIAP2 2620.0 -682.0
BATF 2430.0 7966.0
BCL10 6467.0 6003.0
BCL2 6148.0 -7816.0
BCL2L1 9743.0 8443.0
BCL6 9554.0 9844.0
BIN2 -7555.0 7878.0
BIRC2 8079.0 3449.0
BIRC3 -2270.0 -11079.0
BIRC5 2725.0 4169.0
BLK -5294.0 -3774.0
BLMH 3784.0 3710.0
BLNK -5690.0 -5869.0
BOLA2 1674.0 2264.0
BPI 9613.0 4607.0
BRAF 276.0 2552.0
BRAP 7133.0 5359.0
BRI3 9055.0 9716.0
BRK1 5522.0 8298.0
BRWD1 -2708.0 -9819.0
BST1 10108.0 9972.0
BST2 -8159.0 -3534.0
BTBD1 6622.0 1719.0
BTBD6 -7724.0 -284.0
BTK 7623.0 7870.0
BTLA -588.0 -4978.0
BTN1A1 4261.0 1130.0
BTN2A1 -6903.0 -5956.0
BTN2A2 -9802.0 -10033.0
BTN3A1 -11037.0 -11236.0
BTN3A2 -10593.0 -10503.0
BTN3A3 -10810.0 -11240.0
BTNL8 3327.0 7121.0
BTNL9 -3740.0 -4005.0
BTRC -6845.0 -441.0
C1QA -49.0 7890.0
C1QB 6746.0 8930.0
C1QC 7805.0 9340.0
C1R -10393.0 -4020.0
C1S -6159.0 552.0
C2 6634.0 2959.0
C3 -11179.0 -10489.0
C3AR1 8924.0 8181.0
C4A 5060.0 4740.0
C4B 6359.0 2884.0
C4BPB 3624.0 -4862.0
C5 7727.0 2354.0
C5AR1 9359.0 9709.0
C5AR2 8198.0 8666.0
C6orf120 5882.0 7163.0
C8G -10839.0 -8035.0
CA1 10107.0 9363.0
CAB39 9181.0 8435.0
CALM1 -6645.0 1321.0
CALR 6685.0 6374.0
CAMK2D -9328.0 -10857.0
CAMK2G -646.0 3153.0
CAMP 9421.0 -389.0
CAND1 3497.0 -7234.0
CANT1 7020.0 8333.0
CANX 6838.0 5751.0
CAP1 8192.0 8530.0
CAPN1 7094.0 9770.0
CAPZA1 8666.0 8511.0
CAPZA2 9698.0 8474.0
CAPZB 6100.0 8926.0
CARD11 -11093.0 -10157.0
CARD9 7781.0 6520.0
CASP1 8236.0 2513.0
CASP10 -2054.0 -1105.0
CASP2 -2223.0 235.0
CASP3 191.0 822.0
CASP4 5719.0 6185.0
CASP8 -10359.0 -8523.0
CASP9 5303.0 9133.0
CAT 9793.0 9327.0
CBL 6620.0 8302.0
CBLB -11028.0 -10771.0
CCL2 -10976.0 -11174.0
CCL3 -407.0 -3940.0
CCL4 -11246.0 -6076.0
CCL5 -10668.0 -6900.0
CCND1 -4303.0 -5618.0
CCNF -10194.0 -4195.0
CCR1 9641.0 9012.0
CCR2 10062.0 9973.0
CCR5 -9863.0 -5213.0
CCR6 -2172.0 -9131.0
CCT2 1978.0 -8922.0
CCT8 8723.0 5878.0
CD101 7939.0 2768.0
CD14 9551.0 9658.0
CD160 -11092.0 -8487.0
CD177 9810.0 2861.0
CD180 -749.0 281.0
CD19 -2992.0 -2929.0
CD1A -192.0 -2257.0
CD1C -10681.0 -11235.0
CD1D 8110.0 7717.0
CD200 2256.0 -2190.0
CD200R1 1691.0 -10378.0
CD209 -5894.0 -8203.0
CD22 -3032.0 -4243.0
CD226 -9173.0 -4728.0
CD247 -11271.0 -10327.0
CD27 -3732.0 -9874.0
CD274 -426.0 -8571.0
CD28 -2082.0 -11208.0
CD300A -10110.0 3601.0
CD300C 9411.0 9522.0
CD300E 8420.0 6279.0
CD300LB 9081.0 6385.0
CD300LD 7744.0 6226.0
CD300LF 7312.0 6554.0
CD33 9714.0 7077.0
CD34 -8887.0 -7362.0
CD36 10064.0 9814.0
CD3D -9569.0 -10471.0
CD3E -8133.0 -10695.0
CD3G -9054.0 -10504.0
CD4 3147.0 -5743.0
CD40 -2370.0 -4320.0
CD40LG -4477.0 -10964.0
CD44 8303.0 9047.0
CD46 8744.0 5145.0
CD47 -9758.0 -11025.0
CD53 5300.0 8871.0
CD55 9326.0 9842.0
CD58 6098.0 7272.0
CD59 4075.0 5772.0
CD63 8797.0 10079.0
CD68 8809.0 9128.0
CD70 -1764.0 -6295.0
CD74 -9610.0 -9737.0
CD79A -3264.0 -4267.0
CD79B -6240.0 -6157.0
CD80 -2297.0 -7693.0
CD81 -10685.0 -3573.0
CD86 5511.0 -1419.0
CD8A -9329.0 -8697.0
CD8B -1890.0 -9880.0
CD93 10035.0 10122.0
CD96 -10459.0 -11121.0
CD99 6282.0 9411.0
CDA 9766.0 9792.0
CDC16 -858.0 -5118.0
CDC20 -74.0 5136.0
CDC23 -7178.0 -9273.0
CDC26 3465.0 3689.0
CDC27 1988.0 -5.0
CDC34 8212.0 9329.0
CDC42 8498.0 7640.0
CDH1 -10697.0 -8067.0
CDK13 -9826.0 -1367.0
CDKN1A 3621.0 5190.0
CEACAM1 8749.0 7909.0
CEACAM3 4583.0 7056.0
CEACAM6 8933.0 1336.0
CEACAM8 9111.0 1929.0
CEBPD 8134.0 9779.0
CENPE -3467.0 886.0
CEP290 2753.0 -10189.0
CFB -3014.0 -2968.0
CFD 2998.0 2390.0
CFH -3147.0 -6338.0
CFL1 5851.0 9242.0
CFP 6744.0 8615.0
CGAS 7673.0 6354.0
CHI3L1 4876.0 -2511.0
CHIT1 8764.0 5022.0
CHUK 9198.0 7663.0
CIITA -6172.0 -8589.0
CISH 9673.0 299.0
CKAP4 10101.0 9674.0
CLCF1 -10024.0 -9873.0
CLEC10A -5519.0 -3549.0
CLEC12A 6739.0 3764.0
CLEC2B -6615.0 -7885.0
CLEC2D -10661.0 -11213.0
CLEC4A 9522.0 7775.0
CLEC4C -11151.0 -7325.0
CLEC4D 10004.0 9296.0
CLEC4E 8952.0 8732.0
CLEC4G 6323.0 7841.0
CLEC5A 9544.0 8477.0
CLEC6A 7472.0 6730.0
CLEC7A 9123.0 3695.0
CLTA 8416.0 8998.0
CLTC 9376.0 9720.0
CLU 9512.0 10102.0
CMTM6 8818.0 8010.0
CNKSR1 2877.0 -8713.0
CNKSR2 786.0 -5158.0
CNN2 2919.0 7385.0
CNPY3 7458.0 8402.0
CNTF 7371.0 3797.0
COL1A2 5690.0 684.0
COLEC12 -5943.0 -2495.0
COMMD3 1068.0 -670.0
COMMD9 8869.0 7706.0
COPB1 8213.0 7283.0
COTL1 7691.0 8602.0
CPN2 8266.0 1159.0
CPNE1 -7895.0 1521.0
CPNE3 7732.0 5446.0
CPPED1 9258.0 8367.0
CR1 10079.0 10078.0
CR2 -1342.0 -3900.0
CRACR2A -10740.0 -2401.0
CRCP 910.0 6330.0
CREB1 4878.0 -3476.0
CREBBP -4951.0 6023.0
CREG1 10046.0 10059.0
CRISP3 9520.0 5095.0
CRISPLD2 9508.0 9755.0
CRK 9657.0 9429.0
CRKL 1263.0 5754.0
CRLF1 5043.0 -3947.0
CRTAM -9277.0 -8814.0
CSF1 196.0 -1673.0
CSF1R -7485.0 3452.0
CSF2RA 10124.0 10140.0
CSF2RB 7899.0 7940.0
CSF3R 9184.0 9098.0
CSK -5436.0 7707.0
CSNK2B 1222.0 5287.0
CST3 1960.0 3081.0
CSTB 4302.0 7960.0
CTF1 -3543.0 6324.0
CTLA4 -8325.0 -10298.0
CTNNB1 3201.0 7613.0
CTSA 10083.0 10131.0
CTSB 9526.0 10083.0
CTSC -7528.0 5285.0
CTSD 9620.0 10120.0
CTSF -10487.0 -10487.0
CTSG 9156.0 1689.0
CTSH 6991.0 6545.0
CTSK 7647.0 4123.0
CTSL -5538.0 5895.0
CTSO -7682.0 -10092.0
CTSS 9854.0 7280.0
CTSV -1271.0 -2930.0
CTSZ 8972.0 9860.0
CUL1 -2085.0 -10951.0
CUL2 6801.0 1682.0
CUL3 7151.0 7368.0
CUL5 7502.0 -2980.0
CUL7 -8296.0 2248.0
CXCL1 4484.0 5698.0
CXCL10 5012.0 -11168.0
CXCL2 6689.0 5198.0
CXCL8 3332.0 -907.0
CXCR1 2112.0 7643.0
CXCR2 4038.0 6148.0
CYB5R3 8185.0 9788.0
CYBA -48.0 8901.0
CYBB 9900.0 8910.0
CYFIP1 9724.0 9912.0
CYFIP2 -10558.0 -4935.0
CYLD 2995.0 -11046.0
CYSTM1 9061.0 9479.0
DAB2IP -8411.0 661.0
DAPP1 9222.0 3322.0
DBNL 5107.0 8904.0
DCTN1 -5984.0 7873.0
DCTN2 8504.0 10012.0
DCTN3 325.0 7904.0
DCTN4 7967.0 9572.0
DCTN5 -7505.0 664.0
DCTN6 7871.0 7759.0
DDOST 459.0 8249.0
DDX3X 8543.0 6111.0
DDX41 -566.0 5152.0
DDX58 -10158.0 -10278.0
DEFA1 9407.0 3685.0
DEFA3 8772.0 3736.0
DEFA4 9471.0 3488.0
DEGS1 6718.0 6254.0
DERA 9044.0 8799.0
DET1 -2495.0 -9884.0
DGAT1 3473.0 6135.0
DHX36 562.0 -4982.0
DHX58 -9970.0 -10297.0
DHX9 2911.0 1989.0
DIAPH1 -9216.0 4270.0
DLG1 -295.0 -8414.0
DLG2 -6786.0 -3319.0
DLG3 -10680.0 -10374.0
DLG4 9905.0 8876.0
DNAJC13 9339.0 8451.0
DNAJC3 9077.0 8882.0
DNAJC5 8400.0 9628.0
DNASE1L1 7462.0 9707.0
DNM1 6883.0 3239.0
DNM2 -6816.0 8202.0
DNM3 7927.0 7198.0
DOCK1 6941.0 8390.0
DOCK2 6433.0 8942.0
DOK3 9913.0 9988.0
DPP7 -4737.0 -1700.0
DSC1 2498.0 -9997.0
DSN1 -8825.0 -8996.0
DSP -2099.0 -1252.0
DTX3L 1603.0 -4629.0
DTX4 1850.0 7305.0
DUSP1 4796.0 7997.0
DUSP10 -2707.0 823.0
DUSP16 -4867.0 -5937.0
DUSP2 -10179.0 -6646.0
DUSP3 9937.0 9647.0
DUSP4 -6630.0 -4192.0
DUSP5 -11052.0 -10044.0
DUSP6 7994.0 2589.0
DUSP7 -4748.0 387.0
DUSP8 -10417.0 -9519.0
DYNC1H1 -8881.0 -2533.0
DYNC1I1 7141.0 2722.0
DYNC1I2 8160.0 8196.0
DYNC1LI1 7894.0 6997.0
DYNC1LI2 3494.0 5636.0
DYNLL1 6026.0 6499.0
DYNLL2 -6325.0 -225.0
DYNLT1 1870.0 5508.0
DZIP3 -6745.0 -10932.0
EBI3 -8315.0 6258.0
ECSIT 4110.0 5590.0
EDA 7843.0 -6000.0
EDA2R 8754.0 -7290.0
EDAR -945.0 -9109.0
EDARADD -8365.0 -10129.0
EEA1 8100.0 3526.0
EEF1A1 53.0 -4688.0
EEF2 -2498.0 2707.0
EGF 9244.0 8355.0
EGR1 5173.0 2023.0
EIF2AK2 -8667.0 -6637.0
EIF4A1 8316.0 7635.0
EIF4A2 -4054.0 -10820.0
EIF4A3 7867.0 7462.0
EIF4E 7143.0 4489.0
EIF4E2 8172.0 7181.0
EIF4E3 8714.0 7363.0
EIF4G1 6261.0 9336.0
EIF4G2 7667.0 6879.0
EIF4G3 7434.0 9521.0
ELANE 9880.0 4888.0
ELK1 -355.0 3195.0
ELMO1 4243.0 7282.0
ELMO2 -9506.0 6592.0
ELOB 4867.0 8716.0
ELOC 6598.0 8484.0
ENAH -3230.0 -1566.0
ENPP4 -10919.0 -4181.0
EP300 4311.0 7552.0
EPPIN 3878.0 1579.0
EPX 4309.0 -6896.0
ERAP1 -3226.0 -6281.0
ERAP2 -2069.0 -5352.0
ERBB2 -11251.0 -9287.0
ERBB3 3021.0 -1481.0
EREG -837.0 3226.0
ERP44 8740.0 6170.0
EVL -10613.0 -11193.0
F13A1 9955.0 8516.0
FABP5 4135.0 6969.0
FADD -3611.0 7477.0
FAF2 2326.0 6842.0
FASLG -11268.0 -10430.0
FBXL12 -4301.0 2284.0
FBXL13 2462.0 5869.0
FBXL14 -6789.0 -2829.0
FBXL15 1462.0 6096.0
FBXL16 2754.0 -10861.0
FBXL18 -5426.0 6339.0
FBXL19 7149.0 9883.0
FBXL20 6138.0 5443.0
FBXL22 -8336.0 -7072.0
FBXL3 2372.0 1555.0
FBXL4 8476.0 5165.0
FBXL5 10052.0 9713.0
FBXL8 6606.0 3297.0
FBXO10 -9543.0 -2014.0
FBXO11 8518.0 6652.0
FBXO15 -57.0 -1454.0
FBXO17 6660.0 2069.0
FBXO2 -8087.0 -5594.0
FBXO21 -8475.0 -8331.0
FBXO22 4093.0 -5449.0
FBXO27 -4715.0 -3768.0
FBXO30 5887.0 4626.0
FBXO31 -10431.0 -10713.0
FBXO32 -9356.0 -10029.0
FBXO4 -7804.0 -11129.0
FBXO40 -216.0 3482.0
FBXO41 -3899.0 1696.0
FBXO44 -7880.0 -8023.0
FBXO6 -7080.0 1208.0
FBXO7 9298.0 6606.0
FBXO9 10081.0 9997.0
FBXW11 4585.0 7364.0
FBXW12 -7896.0 -6549.0
FBXW2 544.0 8055.0
FBXW4 -10467.0 -8565.0
FBXW5 -9273.0 5091.0
FBXW7 -5277.0 -3657.0
FBXW8 -9427.0 -6871.0
FBXW9 -10047.0 -416.0
FCAR 9865.0 9508.0
FCER1A -10921.0 -10940.0
FCER1G 6595.0 9147.0
FCER2 -951.0 -3382.0
FCGR1A 9965.0 9575.0
FCGR1B 9834.0 9178.0
FCGR2A 9414.0 9249.0
FCGR2B 901.0 2592.0
FCGR3A -11272.0 -4672.0
FCGR3B 4203.0 4625.0
FCN1 9889.0 9103.0
FGF2 5967.0 3177.0
FGF22 -5885.0 -8493.0
FGF23 -3924.0 -7953.0
FGF7 158.0 -5338.0
FGF9 -8383.0 -6950.0
FGFR1 -8719.0 -822.0
FGFR2 -10068.0 -10229.0
FGFR4 -1760.0 -2742.0
FGL2 8307.0 -4026.0
FGR 6254.0 9666.0
FKBP1A 9920.0 8990.0
FLNA -8145.0 4196.0
FLNB -8575.0 4325.0
FLT3 3904.0 8334.0
FLT3LG -415.0 -11122.0
FN1 10003.0 6211.0
FNTA -147.0 -3320.0
FNTB 7121.0 6362.0
FOLR3 7933.0 7989.0
FOS 6663.0 6569.0
FOXO1 -4402.0 -9319.0
FOXO3 8202.0 9854.0
FPR1 9606.0 9929.0
FPR2 9572.0 9728.0
FRK 23.0 486.0
FRMPD3 -11030.0 -7462.0
FRS2 1765.0 -3137.0
FRS3 8041.0 7694.0
FSCN1 8821.0 8081.0
FTH1 3543.0 5337.0
FTL 8704.0 9324.0
FUCA1 8013.0 8533.0
FUCA2 9577.0 7885.0
FYN -10878.0 -6729.0
FZR1 -7787.0 2875.0
GAA 8448.0 8356.0
GAB1 7926.0 5272.0
GAB2 7546.0 9347.0
GALNS 6719.0 8385.0
GAN 203.0 -1098.0
GATA3 -10441.0 -11237.0
GBP1 -1678.0 -10987.0
GBP2 -1398.0 -7840.0
GBP3 -3205.0 -9116.0
GBP4 -8748.0 -11207.0
GBP5 -8155.0 -10959.0
GBP6 -4475.0 3267.0
GCA 10102.0 9849.0
GDI2 8206.0 7892.0
GFRA2 -9183.0 -5056.0
GGH 5742.0 6109.0
GHDC 4753.0 4443.0
GHR 2063.0 -1273.0
GLA 8923.0 9083.0
GLB1 9091.0 9091.0
GLIPR1 9841.0 6015.0
GLMN -2858.0 -11010.0
GM2A 9396.0 9808.0
GMFG 7620.0 8986.0
GNLY -11065.0 -6613.0
GNS 9627.0 10060.0
GOLGA7 4113.0 4351.0
GPI 3712.0 6865.0
GPR84 9267.0 9312.0
GRAP2 5425.0 4991.0
GRB2 9631.0 9985.0
GRIN2D 5414.0 6550.0
GRN 9760.0 9908.0
GSDMD -1632.0 4125.0
GSN 9281.0 9397.0
GSTO1 9193.0 9858.0
GSTP1 -3317.0 2661.0
GUSB 2374.0 9501.0
GYG1 9474.0 9547.0
GZMM -11118.0 -8768.0
H3C15 5262.5 7402.5
HACE1 -2041.0 -5105.0
HAVCR2 -5218.0 8217.0
HBB 10013.0 8750.0
HBEGF 5089.0 5189.0
HCK 9286.0 9494.0
HCST -10217.0 2226.0
HEBP2 8767.0 8822.0
HECTD1 -2628.0 226.0
HECTD2 -9466.0 -6054.0
HECTD3 -7244.0 4993.0
HECW2 -2797.0 5962.0
HERC1 -8668.0 -6166.0
HERC2 -10344.0 -6770.0
HERC3 -1108.0 2890.0
HERC4 8554.0 4015.0
HERC5 -10767.0 -10994.0
HERC6 -10910.0 -10777.0
HEXB 9386.0 9202.0
HGF 9753.0 8929.0
HGSNAT 4689.0 2250.0
HIF1A 7330.0 7808.0
HK3 9953.0 9940.0
HLA-A -5067.0 570.0
HLA-B -1559.0 1570.0
HLA-C -2829.0 2125.0
HLA-DMA -7081.0 -8794.0
HLA-DMB -4781.0 -8921.0
HLA-DOA -10202.0 -10292.0
HLA-DOB -848.0 -5512.0
HLA-DPA1 -10849.0 -11186.0
HLA-DPB1 -10870.0 -11007.0
HLA-DQA1 -10079.0 -10935.0
HLA-DQA2 -5389.0 -3691.0
HLA-DQB1 -3551.0 -6072.0
HLA-DQB2 -7564.0 -8924.0
HLA-DRA -10267.0 -10796.0
HLA-DRB1 -5355.0 -7118.0
HLA-DRB5 -3678.0 -4235.0
HLA-E -10409.0 2003.0
HLA-F -10598.0 -7440.0
HLA-G -5051.0 159.0
HLA-H -8161.0 452.0
HMGB1 3876.0 -968.0
HMOX1 6942.0 9285.0
HMOX2 -10770.0 -8356.0
HNRNPA2B1 3618.0 4420.0
HNRNPDL -7295.0 -10631.0
HNRNPF -334.0 5326.0
HP 9925.0 10000.0
HPSE 9514.0 8535.0
HRAS -2248.0 -1932.0
HRNR -7455.0 -5209.0
HSP90AA1 5309.0 410.0
HSP90AB1 2247.0 -6319.0
HSP90B1 7042.0 372.0
HSPA1A 8217.0 8368.0
HSPA1B 5673.0 7177.0
HSPA5 8070.0 6713.0
HSPA6 2686.0 7632.0
HSPA8 -8286.0 -8908.0
HSPA9 -3418.0 -7548.0
HTN1 -1993.0 -3136.0
HUWE1 -8883.0 -3494.0
HVCN1 7539.0 4235.0
ICAM1 8336.0 6278.0
ICAM2 -10403.0 -10529.0
ICAM3 6434.0 8725.0
ICAM4 -5897.0 3920.0
ICAM5 6337.0 8803.0
ICMT -3792.0 2455.0
ICOS 1302.0 -10781.0
ICOSLG -215.0 -6953.0
IDH1 10122.0 10092.0
IFI16 5821.0 -734.0
IFI27 4065.0 976.0
IFI30 7703.0 8325.0
IFI35 -5334.0 -3032.0
IFI6 -10955.0 -9419.0
IFIH1 -6483.0 -10093.0
IFIT1 -11050.0 -11015.0
IFIT2 -10433.0 -10888.0
IFIT3 -10171.0 -10608.0
IFIT5 -8873.0 -9728.0
IFITM1 -9049.0 -2712.0
IFITM2 -4186.0 7568.0
IFITM3 -5556.0 1879.0
IFNAR1 9272.0 8485.0
IFNAR2 4783.0 8002.0
IFNG -9241.0 -7900.0
IFNGR1 9796.0 9778.0
IFNGR2 9736.0 9781.0
IFNLR1 -8009.0 -6857.0
IGF2R -1133.0 9240.0
IGHD -2028.0 -4193.0
IGHE -498.0 -5753.0
IGHG1 -1124.0 -7111.0
IGHG2 -5587.0 -6004.0
IGHG3 -507.0 -4089.0
IGHG4 -4038.0 -5940.0
IGHM 1890.0 -2470.0
IGHV1-2 5956.0 -3146.0
IGHV1-46 3766.0 -2976.0
IGHV1-69 2354.0 -2328.0
IGHV2-5 4451.0 -1972.0
IGHV2-70 -3315.0 -2159.0
IGHV3-11 3518.0 -4591.0
IGHV3-13 799.0 -2451.0
IGHV3-23 6032.0 -5092.0
IGHV3-30 2500.0 -5193.0
IGHV3-33 98.0 -4138.0
IGHV3-48 3183.0 -4340.0
IGHV3-53 3131.0 -1786.0
IGHV3-7 4185.0 -3630.0
IGHV4-34 1144.0 -4007.0
IGHV4-39 3786.0 -6542.0
IGHV4-59 4532.0 -5870.0
IGKC 2773.0 -6437.0
IGKV1-12 725.0 -6674.0
IGKV1-16 6217.0 -5451.0
IGKV1-17 -241.0 -2794.0
IGKV1-33 5955.0 -6384.0
IGKV1-5 6127.0 -5162.0
IGKV1D-39 5018.0 -2677.0
IGKV2-28 1440.0 -6662.0
IGKV2-30 5205.0 -5349.0
IGKV2D-28 -7224.0 -2947.0
IGKV3-11 5548.0 -7167.0
IGKV3-15 3174.0 -4687.0
IGKV3-20 3704.0 -5021.0
IGKV3D-20 -1830.0 -4618.0
IGKV4-1 2812.0 -4988.0
IGKV5-2 5226.0 -2682.0
IGLC1 -2813.0 -6176.0
IGLC2 -258.0 -6539.0
IGLC3 -2958.0 -4378.0
IGLC7 -3403.0 -4490.0
IGLV1-36 3522.0 -5030.0
IGLV1-40 163.0 -5497.0
IGLV1-44 4742.0 -5791.0
IGLV1-47 231.0 -6633.0
IGLV1-51 1708.0 -6601.0
IGLV10-54 -5422.0 316.0
IGLV2-11 870.0 -3205.0
IGLV2-14 -5127.0 -8197.0
IGLV2-18 2015.0 -2963.0
IGLV2-23 2029.0 -4201.0
IGLV2-8 4818.0 -5256.0
IGLV3-1 -96.0 -5140.0
IGLV3-12 -7299.0 -6816.0
IGLV3-19 4006.0 -5611.0
IGLV3-21 -975.0 -6062.0
IGLV3-25 -942.0 -5485.0
IGLV3-27 -5365.0 -4834.0
IGLV4-69 1344.0 -2261.0
IGLV5-45 4194.0 -7364.0
IGLV6-57 1834.0 -5837.0
IGLV7-43 4854.0 -2823.0
IGLV7-46 2445.0 -3619.0
IGLV8-61 -3989.0 -5208.0
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IKBKE 387.0 6793.0
IKBKG -3058.0 7903.0
IL10 9734.0 9799.0
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IL10RB 9501.0 9838.0
IL11RA -2776.0 -10746.0
IL12A 1034.0 -8967.0
IL12RB1 -10847.0 -9741.0
IL12RB2 -10883.0 -10308.0
IL13RA1 7666.0 4703.0
IL15 2367.0 -5668.0
IL15RA 4842.0 2414.0
IL16 -10494.0 -2458.0
IL17C -9039.0 -2080.0
IL17RA 9776.0 9824.0
IL17RB -3232.0 -5301.0
IL17RC -915.0 2324.0
IL17RE -3917.0 -4902.0
IL18 8340.0 7387.0
IL18BP -8737.0 -8962.0
IL18R1 -10880.0 5790.0
IL18RAP -11230.0 5060.0
IL19 5979.0 7746.0
IL1B 7489.0 3385.0
IL1R1 9455.0 9194.0
IL1R2 6574.0 9865.0
IL1RAP 3294.0 7375.0
IL1RL1 8858.0 -1567.0
IL1RN 10087.0 9470.0
IL20RB -5244.0 -8058.0
IL21R -11003.0 -10453.0
IL23A -695.0 -11027.0
IL24 -9185.0 -9782.0
IL27 5136.0 8604.0
IL27RA -88.0 4685.0
IL2RA 1007.0 -8826.0
IL2RB -11256.0 -10415.0
IL2RG -10931.0 -9531.0
IL31RA -3367.0 -6695.0
IL32 -8378.0 -9542.0
IL33 -438.0 931.0
IL3RA -10088.0 -10505.0
IL4 -7559.0 -9214.0
IL4R 5715.0 7951.0
IL5RA -8551.0 -10227.0
IL6R 9360.0 8189.0
IL6ST 7914.0 1855.0
IL7 -7208.0 -6964.0
IL7R -4956.0 -11140.0
IL9R -9017.0 -11233.0
ILF2 -2090.0 951.0
IMPDH1 9819.0 9891.0
IMPDH2 -3563.0 -10154.0
INPP5D -10797.0 4515.0
INPPL1 9638.0 9488.0
IP6K2 -10624.0 -3756.0
IQGAP1 7310.0 9366.0
IQGAP2 6198.0 7948.0
IRAK1 2444.0 7601.0
IRAK2 -11058.0 -2404.0
IRAK3 9660.0 9553.0
IRF1 -6320.0 -7043.0
IRF2 6124.0 6880.0
IRF3 -6904.0 -7151.0
IRF4 -202.0 -9788.0
IRF5 7377.0 6623.0
IRF6 -8666.0 -7887.0
IRF7 -8896.0 -5369.0
IRF8 -1809.0 3992.0
IRF9 -9889.0 -8276.0
IRS1 6140.0 8.0
IRS2 8141.0 9618.0
ISG15 -10543.0 -10488.0
ISG20 -10247.0 -8970.0
IST1 260.0 7296.0
ITCH -2889.0 3792.0
ITGA2B 9720.0 9409.0
ITGA4 -6795.0 -10195.0
ITGAL -10958.0 -4334.0
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ITGAV 7467.0 6188.0
ITGAX 3250.0 8762.0
ITGB1 3360.0 -108.0
ITGB2 8042.0 10007.0
ITGB3 9450.0 8690.0
ITGB5 7729.0 7327.0
ITGB7 -10871.0 -10368.0
ITK -7038.0 -10924.0
ITLN1 -9302.0 -3066.0
ITPR1 -5546.0 -5368.0
ITPR2 6833.0 6418.0
ITPR3 -8438.0 -9066.0
JAK1 -10669.0 -4353.0
JAK2 7618.0 374.0
JAK3 8703.0 8585.0
JAML 9043.0 8108.0
JUN 2838.0 4810.0
JUNB 5989.0 7459.0
JUP -4305.0 -4960.0
KBTBD6 -1477.0 2862.0
KBTBD7 3626.0 6975.0
KBTBD8 -1867.0 -3245.0
KCMF1 7123.0 8439.0
KCNAB2 -9549.0 5424.0
KCTD6 4870.0 5068.0
KCTD7 -9176.0 -10293.0
KEAP1 -3358.0 7274.0
KIF11 -140.0 1030.0
KIF15 -4399.0 -3471.0
KIF18A -5118.0 -1862.0
KIF20A 5368.0 4706.0
KIF22 -10995.0 -11246.0
KIF23 8000.0 4957.0
KIF26A -155.0 -6527.0
KIF2A 2515.0 -1329.0
KIF2C 2032.0 104.0
KIF3A -9378.0 -11000.0
KIF3B 3757.0 4323.0
KIF3C 7590.0 9010.0
KIF4A -1703.0 4331.0
KIF5A -7037.0 -7903.0
KIF5B 9540.0 8103.0
KIF5C -2924.0 -10718.0
KIFAP3 -8849.0 -4476.0
KIR2DL1 -10831.0 -5591.0
KIR2DL3 -11106.0 -3807.0
KIR2DL4 -10253.0 794.0
KIR2DS4 -10465.0 -3358.0
KIR3DL1 -11099.0 -6211.0
KIR3DL2 -10723.0 -8112.0
KIT -10872.0 -8011.0
KL 9145.0 9846.0
KLC1 1745.0 7386.0
KLC2 -6674.0 -7322.0
KLC3 8390.0 7398.0
KLC4 -9223.0 -3527.0
KLHL11 -2734.0 -5716.0
KLHL2 9929.0 9615.0
KLHL20 -9314.0 -9256.0
KLHL21 663.0 6548.0
KLHL22 -10423.0 -8088.0
KLHL25 -9206.0 -9406.0
KLHL3 -8309.0 -11239.0
KLHL42 -4575.0 -7103.0
KLHL5 9255.0 2537.0
KLHL9 1973.0 2194.0
KLRB1 -11161.0 -10828.0
KLRC1 -10415.0 -7558.0
KLRC2 -10041.0 -6047.0
KLRD1 -11180.0 -7991.0
KLRF1 -11255.0 -9969.0
KLRG1 -10234.0 -9322.0
KLRK1 -11056.0 -10731.0
KPNA1 4214.0 1618.0
KPNA2 -7397.0 -3307.0
KPNA3 4907.0 248.0
KPNA4 4184.0 4979.0
KPNA5 -6929.0 -11243.0
KPNB1 -1223.0 3575.0
KRAS 3789.0 4070.0
KRT1 6823.0 4687.0
KSR1 326.0 5540.0
KSR2 -3767.0 -1942.0
LAG3 -8785.0 -8611.0
LAIR1 -466.0 8850.0
LAIR2 -9925.0 -5819.0
LAMA5 565.0 -2964.0
LAMP1 1737.0 9127.0
LAMP2 9608.0 8999.0
LAMTOR1 9915.0 9919.0
LAMTOR2 3802.0 9208.0
LAMTOR3 9012.0 7104.0
LAT -9843.0 -10628.0
LAT2 8582.0 9705.0
LCK -10358.0 -10719.0
LCN2 9447.0 6200.0
LCP1 8415.0 8905.0
LCP2 -2426.0 872.0
LEAP2 -3994.0 -3354.0
LGALS3 9602.0 8710.0
LGALS9 2565.0 3635.0
LGMN -3548.0 -2820.0
LILRA1 8877.0 7696.0
LILRA2 9649.0 9523.0
LILRA4 -11199.0 -8907.0
LILRA5 8716.0 9941.0
LILRA6 9761.0 9744.0
LILRB1 7054.0 7665.0
LILRB2 6423.0 9453.0
LILRB3 8958.0 9554.0
LILRB4 8656.0 9836.0
LILRB5 5944.0 8840.0
LIMK1 -2747.0 6617.0
LMNB1 9994.0 9773.0
LMO7 -3935.0 -10042.0
LNPEP -8634.0 -6784.0
LNX1 7669.0 -9609.0
LONRF1 1750.0 5533.0
LPCAT1 -10952.0 2487.0
LPO 8757.0 5426.0
LRG1 6784.0 9458.0
LRR1 -7801.0 -3939.0
LRRC41 5384.0 8643.0
LRRC7 -623.0 -1369.0
LRRFIP1 6242.0 6811.0
LRSAM1 -1526.0 6741.0
LTA 2960.0 -10805.0
LTA4H 9933.0 9541.0
LTB -1343.0 -9611.0
LTBR 9868.0 9916.0
LTF 9374.0 3485.0
LTN1 4330.0 -4383.0
LY86 9457.0 6684.0
LY96 9529.0 8995.0
LYN 7575.0 8379.0
LYPLA1 9192.0 8174.0
LYZ 9774.0 5791.0
MADCAM1 -936.0 4452.0
MAGT1 574.0 3711.0
MALT1 -1301.0 -11074.0
MAN2B1 7665.0 7139.0
MANBA 9330.0 6620.0
MAOA 9886.0 9426.0
MAP2K1 9163.0 9879.0
MAP2K2 185.0 8452.0
MAP2K3 8978.0 9308.0
MAP2K4 6895.0 7431.0
MAP2K6 9435.0 9577.0
MAP2K7 -2754.0 4813.0
MAP3K1 5466.0 5938.0
MAP3K11 6025.0 8985.0
MAP3K14 -10222.0 -9826.0
MAP3K3 8280.0 9287.0
MAP3K7 1546.0 4274.0
MAP3K8 -7139.0 8928.0
MAPK1 1052.0 9260.0
MAPK10 6734.0 3872.0
MAPK11 7257.0 1843.0
MAPK12 1925.0 -1837.0
MAPK13 -8511.0 5595.0
MAPK14 9907.0 9606.0
MAPK3 8931.0 9626.0
MAPK7 -10125.0 5069.0
MAPK8 -1061.0 -9914.0
MAPK9 -6530.0 -1870.0
MAPKAP1 2536.0 5925.0
MAPKAPK2 -10572.0 6892.0
MAPKAPK3 7493.0 9250.0
MARK3 9434.0 9486.0
MASP2 2089.0 -6883.0
MAVS 6465.0 9067.0
MCEMP1 10086.0 10124.0
MCL1 7723.0 7150.0
MEF2A 9000.0 8162.0
MEF2C 6943.0 -2868.0
MEFV 9094.0 9246.0
METTL7A 8352.0 6827.0
MEX3C -11104.0 -8577.0
MGAM 8661.0 9588.0
MGRN1 1713.0 6976.0
MGST1 10098.0 9993.0
MIB2 -10461.0 -7734.0
MICA -2722.0 -4839.0
MICB -454.0 4384.0
MIF -4739.0 -1332.0
MKRN1 9789.0 8565.0
MLEC 1226.0 3680.0
MLST8 -3991.0 2978.0
MME -1752.0 1424.0
MMP1 9240.0 6657.0
MMP25 6740.0 9386.0
MMP8 9818.0 1522.0
MMP9 9225.0 9700.0
MNDA 10027.0 9394.0
MOSPD2 9799.0 8045.0
MPO 9985.0 4616.0
MRAS -10710.0 298.0
MRC1 -6259.0 4719.0
MRC2 4574.0 -2049.0
MRE11 -4492.0 -8162.0
MS4A2 -5654.0 -10490.0
MS4A3 8707.0 -2464.0
MSN -4366.0 7815.0
MT2A -8984.0 -2940.0
MTAP 3191.0 -6757.0
MTOR -10419.0 -3248.0
MUC1 8159.0 7011.0
MUC12 -8506.0 -9690.0
MUC16 377.0 -5584.0
MUC20 -2625.0 -6328.0
MUC4 643.0 -4710.0
MUC5B -8416.0 -622.0
MUC6 -3460.0 -1745.0
MUCL1 -1878.0 -1414.0
MVP 4779.0 8093.0
MX1 -10700.0 -10788.0
MX2 -6184.0 -3158.0
MYC 8429.0 -2186.0
MYD88 8651.0 8344.0
MYH9 1879.0 8348.0
MYLIP -4440.0 -1671.0
MYO10 9409.0 9473.0
MYO1C 6395.0 2929.0
MYO5A 6789.0 7727.0
MYO9B 513.0 8592.0
NANOG 5462.0 317.0
NAPRT 6522.0 8450.0
NBEAL2 2363.0 8445.0
NCAM1 -11155.0 -5990.0
NCF1 8576.0 7083.0
NCF2 9748.0 9694.0
NCF4 9697.0 9856.0
NCK1 -9250.0 -9113.0
NCKAP1 6871.0 8168.0
NCKAP1L 3966.0 9566.0
NCKIPSD 957.0 1858.0
NCR1 -11274.0 -9812.0
NCR3 -10684.0 -6944.0
NCR3LG1 -10509.0 -10334.0
NCSTN 9503.0 9869.0
NDC1 -9151.0 -11223.0
NDN 3640.0 4458.0
NDUFC2 1951.0 7994.0
NECTIN2 6708.0 9898.0
NEDD4 -884.0 7132.0
NEDD4L 8246.0 8260.0
NEFL 2738.0 -8726.0
NEU1 9336.0 9571.0
NF1 -1234.0 4267.0
NF2 -9157.0 -819.0
NFAM1 9370.0 9863.0
NFATC1 -9648.0 -4795.0
NFATC2 -11185.0 -10445.0
NFATC3 -10822.0 -10053.0
NFKB1 7857.0 6377.0
NFKB2 3069.0 -1167.0
NFKBIA 6855.0 7374.0
NFKBIB -9679.0 5479.0
NFKBIE 1816.0 -5102.0
NHLRC3 4253.0 1252.0
NIT2 -7855.0 -11064.0
NKIRAS1 2619.0 689.0
NKIRAS2 9581.0 9936.0
NLRC3 -11019.0 -10784.0
NLRC4 9962.0 10003.0
NLRC5 -8425.0 -8806.0
NLRP1 -1438.0 -6109.0
NLRP3 9708.0 8944.0
NLRX1 3934.0 9137.0
NME2 2395.0 3054.0
NOD1 -10930.0 -10348.0
NOD2 9408.0 8613.0
NOS1 4727.0 -183.0
NOS3 5934.0 -5046.0
NPC2 6632.0 5511.0
NPDC1 7696.0 -3669.0
NPEPPS 9087.0 8223.0
NRAS 7321.0 4878.0
NRG1 8713.0 914.0
NRG4 1196.0 -3291.0
NUP107 -4463.0 -10317.0
NUP133 -4339.0 -4616.0
NUP153 -7195.0 -2408.0
NUP155 -4644.0 -9292.0
NUP160 -2518.0 -10020.0
NUP188 -9467.0 -9810.0
NUP205 -8533.0 -9667.0
NUP210 -10480.0 -5943.0
NUP214 8588.0 8152.0
NUP35 -4281.0 -10256.0
NUP37 3188.0 3613.0
NUP42 1567.0 -5400.0
NUP43 -55.0 -10161.0
NUP50 6614.0 4617.0
NUP54 2794.0 -9194.0
NUP58 9637.0 9212.0
NUP62 3053.0 1921.0
NUP85 1119.0 -2732.0
NUP88 -7116.0 -10078.0
NUP93 -9095.0 -8944.0
NUP98 208.0 4310.0
OAS1 -7996.0 -7280.0
OAS2 -10893.0 -10641.0
OAS3 -10655.0 -11056.0
OASL -10486.0 -7346.0
OLFM4 9728.0 7424.0
OLR1 8411.0 -2056.0
OPRD1 -4129.0 -3347.0
OPRM1 4355.0 1404.0
ORAI1 -9219.0 -1368.0
ORAI2 775.0 6855.0
ORM1 8665.0 8363.0
ORM2 -4938.0 149.0
ORMDL3 -9307.0 -7231.0
OSBPL1A -7890.0 -3076.0
OSCAR 9651.0 9561.0
OSM 7132.0 8038.0
OSMR -2892.0 -63.0
OSTF1 6441.0 8058.0
OTUD5 -9093.0 2293.0
P2RX1 7223.0 9888.0
P2RX7 5741.0 3066.0
P4HB 6474.0 9641.0
PA2G4 -997.0 -1395.0
PADI2 9767.0 9703.0
PAFAH1B2 7693.0 7761.0
PAG1 2942.0 5215.0
PAK1 9711.0 7682.0
PAK2 9019.0 8433.0
PAK3 -1134.0 -4249.0
PANX1 6263.0 6597.0
PAQR3 -1798.0 -2543.0
PCBP2 6380.0 5411.0
PDAP1 -4620.0 8599.0
PDCD1 -7403.0 -5037.0
PDCD1LG2 1843.0 -4094.0
PDCD4 -7921.0 -11050.0
PDE12 -4881.0 -2573.0
PDE3B -7149.0 -10938.0
PDE6D 2041.0 6166.0
PDGFA 6115.0 5392.0
PDGFB -4645.0 -8897.0
PDGFRA 2481.0 6753.0
PDGFRB -11134.0 -5992.0
PDIA3 2037.0 4838.0
PDPK1 2392.0 7816.0
PDXK 9135.0 9342.0
PDZD11 -9036.0 -585.0
PEA15 -3644.0 -5134.0
PEBP1 -8004.0 -10339.0
PECAM1 8136.0 8308.0
PELI1 9064.0 5690.0
PELI2 9242.0 9060.0
PELI3 5708.0 8764.0
PFKL -4964.0 514.0
PGAM1 9980.0 9987.0
PGLYRP1 8816.0 7750.0
PGLYRP2 -9721.0 3276.0
PGM1 -2421.0 7047.0
PGM2 9878.0 9866.0
PGRMC1 9328.0 7693.0
PHB -4398.0 564.0
PI3 8550.0 -782.0
PIANP 691.0 -1251.0
PIAS1 9212.0 7268.0
PIGR 1807.0 -551.0
PIK3AP1 6149.0 8581.0
PIK3C3 6605.0 573.0
PIK3CA 6889.0 4182.0
PIK3CB 9838.0 9248.0
PIK3CD 82.0 7288.0
PIK3R1 -7197.0 -8942.0
PIK3R2 2459.0 5820.0
PIK3R3 -11107.0 -8159.0
PIK3R4 -267.0 -2209.0
PILRA 6470.0 7619.0
PILRB -10165.0 -9335.0
PIM1 9420.0 7031.0
PIN1 -9660.0 3728.0
PITPNA 6122.0 7384.0
PJA1 -8316.0 -7296.0
PJA2 7725.0 7785.0
PKM 9904.0 9954.0
PLA2G6 -10753.0 -10993.0
PLAC8 6624.0 9383.0
PLAU 1698.0 5458.0
PLAUR 8428.0 9009.0
PLCG1 -6360.0 -11043.0
PLCG2 -4618.0 6826.0
PLD1 9826.0 9945.0
PLD2 7087.0 7779.0
PLD3 8640.0 7098.0
PLD4 -11266.0 -11216.0
PLEKHO2 6392.0 9014.0
PLPP5 -4861.0 -6194.0
PML -6449.0 -6720.0
PNP 9167.0 8393.0
POLR1C -5223.0 -10095.0
POLR1D 8331.0 5916.0
POLR2E 6766.0 8343.0
POLR2F -2307.0 6746.0
POLR2H 653.0 -2264.0
POLR2K 1881.0 -1885.0
POLR2L 126.0 7246.0
POLR3A -8082.0 -1838.0
POLR3B -7085.0 -3891.0
POLR3C -238.0 -5145.0
POLR3D -9064.0 -10412.0
POLR3E -9777.0 -9560.0
POLR3F 3481.0 -7424.0
POLR3G -3249.0 -4541.0
POLR3GL -9923.0 -272.0
POLR3H -7488.0 -8017.0
POLR3K -815.0 -1133.0
POM121 -8969.0 -3230.0
POM121C -9525.0 -1010.0
POMC 1489.0 3391.0
POU2F1 -609.0 2898.0
PPBP 7528.0 6376.0
PPIA -7248.0 -2108.0
PPIE -5515.0 -9064.0
PPL -5435.0 3144.0
PPM1B 2858.0 6457.0
PPP1CB 8657.0 6666.0
PPP1CC 9200.0 4868.0
PPP2CA 8810.0 8328.0
PPP2CB 8482.0 7631.0
PPP2R1A -3087.0 6994.0
PPP2R1B 2503.0 437.0
PPP2R5A -903.0 6957.0
PPP2R5B 5288.0 7952.0
PPP2R5C -10420.0 -7112.0
PPP2R5D -6508.0 4985.0
PPP2R5E 715.0 540.0
PPP3CA 6208.0 7300.0
PPP3CB 8057.0 6833.0
PPP3R1 8998.0 8570.0
PPP5C -9397.0 -2360.0
PRCP 8403.0 8843.0
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PRDX6 9609.0 8969.0
PRKACA 9885.0 10068.0
PRKACB -9852.0 -10936.0
PRKCB 5395.0 8378.0
PRKCD 9393.0 9642.0
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PRKCQ -10709.0 -10890.0
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PRLR -4989.0 -9976.0
PROS1 9065.0 7937.0
PRR5 -11173.0 -8620.0
PRTN3 9645.0 4535.0
PSAP 7519.0 7770.0
PSEN1 7889.0 8878.0
PSMA1 8278.0 7406.0
PSMA2 5830.0 5666.0
PSMA3 4646.0 -7621.0
PSMA4 3950.0 -1036.0
PSMA5 -2119.0 -3983.0
PSMA6 6893.0 5865.0
PSMA7 3550.0 8554.0
PSMB1 3915.0 4224.0
PSMB10 -7878.0 -1272.0
PSMB2 2664.0 4928.0
PSMB3 4971.0 8382.0
PSMB4 -3175.0 4911.0
PSMB5 6561.0 9138.0
PSMB6 1312.0 8784.0
PSMB7 8034.0 9051.0
PSMB8 -4481.0 75.0
PSMB9 -9105.0 -10433.0
PSMC1 6759.0 7782.0
PSMC2 -2524.0 4517.0
PSMC3 -4971.0 4984.0
PSMC4 -10757.0 -336.0
PSMC5 -3424.0 2764.0
PSMC6 8812.0 6000.0
PSMD1 7679.0 7587.0
PSMD10 2067.0 2450.0
PSMD11 6914.0 6824.0
PSMD12 9011.0 5710.0
PSMD13 3157.0 7205.0
PSMD14 2891.0 3041.0
PSMD2 4352.0 8396.0
PSMD3 -2243.0 6367.0
PSMD4 6858.0 9449.0
PSMD5 2770.0 4781.0
PSMD6 8841.0 8304.0
PSMD7 6534.0 6147.0
PSMD8 739.0 7117.0
PSMD9 3580.0 9001.0
PSME1 -7256.0 -7913.0
PSME2 -5548.0 -10355.0
PSME3 9120.0 8239.0
PSME4 -5205.0 -3127.0
PSMF1 6709.0 6770.0
PSPN 6438.0 2245.0
PSTPIP1 4146.0 9452.0
PTAFR 9791.0 9983.0
PTEN 9191.0 8752.0
PTGES2 -6197.0 -3780.0
PTGS2 6044.0 3823.0
PTK2 7786.0 3481.0
PTK2B 2270.0 9537.0
PTPN1 -8327.0 7695.0
PTPN11 4691.0 6614.0
PTPN12 7921.0 9275.0
PTPN13 -9422.0 -7282.0
PTPN14 444.0 -2588.0
PTPN18 -1694.0 8540.0
PTPN2 7776.0 8909.0
PTPN20 2731.0 -4226.0
PTPN22 -8401.0 2469.0
PTPN23 -4984.0 2588.0
PTPN3 -742.0 873.0
PTPN4 -10946.0 -10632.0
PTPN6 -691.0 7862.0
PTPN7 -10607.0 -6009.0
PTPN9 -2214.0 8622.0
PTPRA -10794.0 3851.0
PTPRB -9635.0 -4262.0
PTPRC -3326.0 4087.0
PTPRJ 4613.0 9148.0
PTPRN2 3436.0 5350.0
PTX3 8865.0 4044.0
PVR 9468.0 9391.0
PYCARD 8329.0 9425.0
PYGB -5192.0 3500.0
PYGL 10071.0 9926.0
QPCT 9809.0 9852.0
QSOX1 9451.0 10048.0
RAB10 9303.0 9477.0
RAB14 8215.0 7014.0
RAB18 9425.0 7287.0
RAB24 2905.0 6201.0
RAB27A 9164.0 8675.0
RAB31 9956.0 9895.0
RAB37 -11095.0 -6455.0
RAB3A 7816.0 8757.0
RAB3D 9596.0 9946.0
RAB44 4572.0 -693.0
RAB4B -7808.0 7089.0
RAB5B 3295.0 7820.0
RAB5C 7846.0 9422.0
RAB6A 8487.0 8616.0
RAB7A 8897.0 9367.0
RAB9B -5682.0 -4620.0
RAC1 9052.0 9614.0
RAC2 -7677.0 6828.0
RACGAP1 3340.0 3770.0
RAE1 4777.0 6291.0
RAF1 8477.0 8327.0
RAG1 -10678.0 -8094.0
RALA 7124.0 1151.0
RALGDS -11080.0 -10024.0
RANBP2 4453.0 -2222.0
RANBP9 3568.0 6133.0
RAP1A 8688.0 6973.0
RAP1B -2703.0 4941.0
RAP1GAP 10118.0 7895.0
RAP2B -6678.0 3725.0
RAP2C 426.0 5484.0
RAPGEF1 -10851.0 -864.0
RAPGEF2 6349.0 7882.0
RAPGEF3 1224.0 -2066.0
RASA1 4308.0 2428.0
RASA2 -7280.0 -1511.0
RASA3 -10301.0 -9692.0
RASA4 -10075.0 -10354.0
RASAL1 1927.0 -1545.0
RASAL2 2199.0 20.0
RASAL3 -10844.0 -9650.0
RASGEF1A -10612.0 1500.0
RASGRF1 -5249.0 -2699.0
RASGRF2 -4591.0 -10584.0
RASGRP1 -9849.0 -11029.0
RASGRP2 -7479.0 -7190.0
RASGRP3 -4981.0 -8320.0
RASGRP4 9926.0 9901.0
RBBP6 7135.0 -3752.0
RBCK1 -4700.0 4686.0
RBSN -7312.0 339.0
RBX1 1418.0 4877.0
RCE1 -3787.0 -2010.0
RCHY1 8112.0 5797.0
REL 2568.0 4765.0
RELA -7305.0 2739.0
RELB 3146.0 4566.0
RET -10107.0 -2874.0
RETN 9209.0 9105.0
RGL1 7936.0 8025.0
RGL2 4873.0 9252.0
RGL3 8964.0 5107.0
RHOA 8351.0 8888.0
RHOF -11160.0 -10418.0
RHOG 7549.0 9255.0
RHOU 7924.0 9743.0
RICTOR -3978.0 -9726.0
RILP 9327.0 8347.0
RIPK1 -10879.0 -4699.0
RIPK2 1665.0 2297.0
RIPK3 -5133.0 7348.0
RLIM 5748.0 5413.0
RNASE2 10073.0 10107.0
RNASE3 9238.0 6921.0
RNASE6 8782.0 6121.0
RNASEL 7610.0 8612.0
RNASET2 5158.0 6487.0
RNF111 6509.0 6215.0
RNF114 6745.0 2760.0
RNF115 -9065.0 -5995.0
RNF123 3943.0 8163.0
RNF125 -8706.0 -9750.0
RNF126 -9628.0 -7680.0
RNF130 8891.0 9015.0
RNF135 8493.0 9341.0
RNF138 8936.0 2161.0
RNF14 3011.0 5025.0
RNF144B 8927.0 8721.0
RNF19A -8656.0 -6854.0
RNF19B 7545.0 6682.0
RNF213 -10439.0 -9870.0
RNF216 -8194.0 -8556.0
RNF217 9908.0 7097.0
RNF220 -9365.0 739.0
RNF25 -8613.0 -1512.0
RNF34 -7739.0 -719.0
RNF4 -10891.0 -3374.0
RNF41 8699.0 9075.0
RNF6 5905.0 3868.0
RNF7 6703.0 8617.0
ROCK1 8315.0 7930.0
RORA -10511.0 -10952.0
RORC -6496.0 -10569.0
RPLP0 3127.0 -1531.0
RPS27A -3555.0 -7070.0
RPS6KA1 -105.0 9153.0
RPS6KA2 -5428.0 3882.0
RPS6KA3 2859.0 3437.0
RPS6KA5 -3980.0 -11177.0
RSAD2 -10804.0 -10793.0
S100A1 -7792.0 -5913.0
S100A11 9254.0 9466.0
S100A12 10088.0 10121.0
S100A8 10041.0 10093.0
S100A9 10110.0 10116.0
S100B -8212.0 -1271.0
S100P 5927.0 9300.0
S1PR1 -10750.0 -4787.0
SAMHD1 7413.0 6999.0
SAR1B 8795.0 5984.0
SARM1 -10456.0 -10950.0
SCAMP1 7532.0 -1630.0
SDCBP 9944.0 9687.0
SEC13 2125.0 6861.0
SEC22B 8663.0 4943.0
SEC23A 8776.0 6905.0
SEC24A 8318.0 7788.0
SEC24B 1663.0 5398.0
SEC24C -9662.0 3561.0
SEC24D 8017.0 8795.0
SEC31A 1743.0 2474.0
SEC61A1 5496.0 7020.0
SEC61A2 -8826.0 -9671.0
SEC61B 4953.0 8362.0
SEC61G 7533.0 3614.0
SEH1L 7189.0 -8511.0
SELL 9694.0 9159.0
SEM1 993.0 5942.0
SERPINA1 9571.0 9817.0
SERPINB1 10061.0 9986.0
SERPINB10 9936.0 8636.0
SERPINB2 10012.0 9937.0
SERPINB6 3579.0 7946.0
SERPING1 -6329.0 -10968.0
SH2B1 -6398.0 -6874.0
SH2D1A -10772.0 -11062.0
SH2D1B -11242.0 -10874.0
SH3KBP1 4345.0 7311.0
SH3RF1 -7501.0 -1839.0
SHC1 -3416.0 5815.0
SHC3 9229.0 -1001.0
SHOC2 8573.0 7262.0
SIAH1 -5833.0 454.0
SIAH2 9783.0 8092.0
SIGIRR -9900.0 -8613.0
SIGLEC1 -11014.0 -10562.0
SIGLEC10 3815.0 8466.0
SIGLEC11 8094.0 7943.0
SIGLEC12 -2137.0 4739.0
SIGLEC14 8633.0 4157.0
SIGLEC15 10015.0 9518.0
SIGLEC16 9890.0 9405.0
SIGLEC5 8330.0 8707.0
SIGLEC6 -8702.0 -7931.0
SIGLEC7 4975.0 9740.0
SIGLEC8 -5623.0 -5546.0
SIGLEC9 9722.0 10062.0
SIKE1 3865.0 -7566.0
SIPA1 -9197.0 7184.0
SIRPA 10106.0 10119.0
SIRPB1 7638.0 9107.0
SKP1 8120.0 2700.0
SKP2 -2615.0 -7161.0
SLAMF6 -11132.0 -10363.0
SLAMF7 -11007.0 -9711.0
SLC11A1 9129.0 9947.0
SLC15A4 -8597.0 6968.0
SLC27A2 6501.0 -6385.0
SLC2A3 9614.0 9612.0
SLC2A5 7731.0 -721.0
SLC44A2 -8609.0 5338.0
SLCO4C1 -10306.0 5158.0
SLPI 9291.0 3565.0
SMAD3 -10084.0 -10081.0
SMARCA4 -2731.0 7803.0
SMURF1 -9318.0 2452.0
SMURF2 -9128.0 -7045.0
SNAP23 9586.0 8642.0
SNAP29 -1741.0 8902.0
SNRPA1 -7002.0 -9934.0
SOCS1 -219.0 6051.0
SOCS2 4901.0 -4080.0
SOCS3 9830.0 10110.0
SOCS5 6009.0 2808.0
SOD1 -1389.0 -3334.0
SOD2 4529.0 4854.0
SOS1 3534.0 -7412.0
SOS2 9141.0 8628.0
SP100 5494.0 4353.0
SPRED1 -7983.0 -6504.0
SPRED2 -404.0 8453.0
SPRED3 -6894.0 -4695.0
SPSB1 -2844.0 4000.0
SPSB2 -9283.0 1413.0
SPTA1 9470.0 6216.0
SPTAN1 -10174.0 -8889.0
SPTB 9958.0 9302.0
SPTBN1 -6572.0 -6164.0
SPTBN2 -5447.0 -3871.0
SPTBN5 -7557.0 -461.0
SQSTM1 4693.0 4549.0
SRC -6857.0 -7229.0
SRP14 4915.0 7324.0
STAT1 -7385.0 -11118.0
STAT2 -5116.0 -9909.0
STAT3 8512.0 8606.0
STAT4 -11142.0 -11112.0
STAT5A 6437.0 7973.0
STAT5B 4758.0 7433.0
STAT6 2936.0 7753.0
STBD1 3893.0 5802.0
STIM1 -9148.0 7796.0
STING1 6507.0 4536.0
STK10 -10951.0 4288.0
STK11IP -6497.0 6947.0
STOM 1151.0 7088.0
STUB1 -7516.0 3468.0
STX1A -9454.0 1322.0
STX3 9343.0 8695.0
STX4 -7285.0 5736.0
STXBP2 9017.0 9835.0
SUGT1 7602.0 -482.0
SUMO1 7968.0 6798.0
SURF4 3781.0 8016.0
SVIP 4431.0 1345.0
SYK 9464.0 9848.0
SYNGAP1 -6138.0 -8178.0
SYNGR1 -8211.0 -736.0
TAB1 6623.0 5746.0
TAB2 9197.0 5726.0
TAB3 3912.0 3647.0
TALDO1 10039.0 9995.0
TANK 8959.0 7267.0
TAP1 -8207.0 -9297.0
TAP2 -9895.0 -10077.0
TAPBP -5450.0 4788.0
TARM1 8354.0 4978.0
TAX1BP1 7469.0 5996.0
TBC1D10C -10716.0 -9378.0
TBK1 5846.0 2973.0
TCIRG1 1085.0 9058.0
TCN1 8724.0 3700.0
TCP1 7677.0 2853.0
TEC 8165.0 7953.0
TGFA 7935.0 9686.0
TGFB1 -2566.0 6745.0
THEM4 -5349.0 -11202.0
THOP1 -8479.0 -6598.0
TICAM1 6742.0 6552.0
TICAM2 9182.0 4768.0
TIFA 6543.0 4608.0
TIMP1 6136.0 9944.0
TIMP2 9988.0 10081.0
TIRAP 262.0 7730.0
TKFC 5127.0 5512.0
TLN1 7865.0 9661.0
TLR1 9828.0 8868.0
TLR10 -122.0 -3607.0
TLR2 9930.0 9118.0
TLR3 -9935.0 -9836.0
TLR4 9494.0 9617.0
TLR5 9746.0 9721.0
TLR6 9634.0 9209.0
TLR7 8636.0 -4675.0
TLR8 9957.0 9871.0
TLR9 -10413.0 -138.0
TMBIM1 6724.0 9228.0
TMC6 -8623.0 -9689.0
TMEM179B 821.0 1646.0
TMEM30A 9288.0 7807.0
TMEM63A -1958.0 -10069.0
TNF -3598.0 -6316.0
TNFAIP3 -10682.0 -6292.0
TNFAIP6 8375.0 9294.0
TNFRSF11A -9851.0 -3380.0
TNFRSF12A 3257.0 8290.0
TNFRSF13B -2994.0 -364.0
TNFRSF13C -3350.0 -3167.0
TNFRSF14 -7323.0 -3106.0
TNFRSF17 5446.0 -9209.0
TNFRSF18 -7259.0 -6691.0
TNFRSF1A 9563.0 9913.0
TNFRSF1B 1146.0 8282.0
TNFRSF25 -3579.0 -11215.0
TNFRSF4 730.0 -8796.0
TNFRSF8 500.0 7169.0
TNFRSF9 -1897.0 2038.0
TNFSF11 -2935.0 -3107.0
TNFSF12 7555.0 7452.0
TNFSF13 8727.0 8849.0
TNFSF13B 8900.0 6912.0
TNFSF14 -8242.0 4622.0
TNFSF15 5556.0 -4557.0
TNFSF4 2025.0 3937.0
TNFSF8 6615.0 -9459.0
TNFSF9 -8249.0 -3555.0
TNIP2 -1490.0 7359.0
TOLLIP 8447.0 9165.0
TOM1 9299.0 9952.0
TP53 -7284.0 -8934.0
TPP2 1634.0 -9998.0
TPR -1066.0 -7983.0
TRAC -7973.0 -11179.0
TRAF2 -9898.0 -9879.0
TRAF3 2694.0 -5265.0
TRAF6 -1767.0 2089.0
TRAF7 6671.0 9722.0
TRAIP -10021.0 -9806.0
TRAPPC1 5277.0 9110.0
TRAT1 5825.0 -10715.0
TRAV19 -7386.0 -9425.0
TRAV29DV5 -4800.0 -10814.0
TRAV8-4 -7363.0 -7382.0
TRBC1 -10647.0 -10844.0
TRBV12-3 -9339.0 -9872.0
TRBV7-9 -8541.0 -8307.0
TREM1 5997.0 7651.0
TREML1 8438.0 8514.0
TREML2 -1045.0 7503.0
TREML4 4884.0 6470.0
TREX1 38.0 -316.0
TRIB3 -7572.0 -1651.0
TRIM10 7218.0 7509.0
TRIM11 -8090.0 2058.0
TRIM14 -9775.0 -1041.0
TRIM17 -10645.0 -4791.0
TRIM2 1204.0 -6786.0
TRIM21 1612.0 3394.0
TRIM22 -7977.0 -8915.0
TRIM25 8976.0 8487.0
TRIM26 -10208.0 -2311.0
TRIM3 -3515.0 1137.0
TRIM32 -10314.0 -9171.0
TRIM34 7503.0 4812.0
TRIM35 -9092.0 -6277.0
TRIM36 -5451.0 -4846.0
TRIM37 -4576.0 -5985.0
TRIM38 5925.0 2170.0
TRIM39 -10551.0 -4566.0
TRIM4 4607.0 2467.0
TRIM41 -7799.0 6954.0
TRIM45 -4293.0 -6836.0
TRIM46 1677.0 -10496.0
TRIM5 -6406.0 -3703.0
TRIM56 -9020.0 -5699.0
TRIM6 190.0 1152.0
TRIM62 -10126.0 -6044.0
TRIM68 -10633.0 -9534.0
TRIM69 -6071.0 -8400.0
TRIM71 9234.0 9601.0
TRIM8 8123.0 9263.0
TRIM9 263.0 1863.0
TRIP12 5055.0 8104.0
TRPC1 -2448.0 -10832.0
TRPM2 9480.0 9785.0
TSPAN14 -706.0 8468.0
TUBB -9096.0 -626.0
TUBB4B 6246.0 7789.0
TXK -9905.0 -10778.0
TXLNA 1637.0 -298.0
TXN 8317.0 8729.0
TXNDC5 6834.0 -3539.0
TXNIP -9337.0 -6548.0
TYK2 4430.0 8605.0
TYROBP 6139.0 8494.0
UBA1 2505.0 8454.0
UBA3 9502.0 7030.0
UBA5 2339.0 -9858.0
UBA52 -1875.0 3023.0
UBA6 4933.0 3279.0
UBA7 -5544.0 -5471.0
UBAC1 8616.0 8637.0
UBB 8251.0 6157.0
UBC -1915.0 5825.0
UBE2A 7726.0 8032.0
UBE2B 8648.0 6410.0
UBE2C 3717.0 5687.0
UBE2D1 9825.0 9491.0
UBE2D2 2673.0 5593.0
UBE2D3 9443.0 8783.0
UBE2D4 -5562.0 -10226.0
UBE2E1 8528.0 6289.0
UBE2E2 6610.0 -195.0
UBE2E3 5727.0 5064.0
UBE2F 960.0 8586.0
UBE2G1 3646.0 5958.0
UBE2G2 719.0 -9159.0
UBE2H 7660.0 8041.0
UBE2J1 10056.0 9062.0
UBE2J2 7098.0 9468.0
UBE2K 8831.0 6196.0
UBE2L3 7416.0 7794.0
UBE2L6 -8809.0 -9855.0
UBE2M 2776.0 9251.0
UBE2N 4087.0 2050.0
UBE2O 3953.0 2699.0
UBE2Q1 2002.0 6541.0
UBE2Q2 -8213.0 -9964.0
UBE2R2 8380.0 9338.0
UBE2S 3693.0 5680.0
UBE2V1 6665.0 5995.0
UBE2V2 6427.0 1996.0
UBE2W 9632.0 7147.0
UBE2Z -9598.0 -6520.0
UBE3A 5897.0 2802.0
UBE3B -1608.0 4236.0
UBE3C 7039.0 6246.0
UBE3D -7298.0 -9854.0
UBE4A 2454.0 2894.0
UBOX5 -8909.0 4492.0
UBR1 -5289.0 -1585.0
UBR2 3389.0 5400.0
UBR4 -6416.0 1703.0
UFL1 -708.0 -6987.0
ULBP3 -719.0 -437.0
UNC13D -1509.0 9298.0
UNC93B1 -1309.0 6224.0
UNKL -4160.0 292.0
USP18 -10888.0 -10755.0
VAMP2 -9677.0 -10779.0
VAMP3 9204.0 8284.0
VAMP7 10053.0 10044.0
VAMP8 2890.0 6767.0
VAPA 9732.0 9322.0
VASP 7010.0 8703.0
VAT1 9437.0 10049.0
VAV1 5553.0 8731.0
VAV2 -5033.0 -1339.0
VAV3 -6160.0 7203.0
VCL 7488.0 7955.0
VCP 3600.0 7754.0
VEGFA 8464.0 8215.0
VHL -212.0 6007.0
VIM 9794.0 10020.0
VNN1 9174.0 9668.0
VPS35L 5526.0 7038.0
VRK3 -7245.0 5798.0
VTN -5291.0 730.0
VWF 6949.0 7780.0
WAS 8258.0 9323.0
WASF1 10091.0 10132.0
WASF2 7535.0 9576.0
WASF3 8142.0 7240.0
WASL 899.0 1391.0
WDR83 -3139.0 6345.0
WIPF1 -5700.0 3866.0
WIPF2 2722.0 7125.0
WSB1 8808.0 8048.0
WWP1 813.0 -10536.0
XAF1 -9652.0 -10960.0
XRCC5 6475.0 5318.0
XRCC6 -2658.0 -1055.0
YES1 -11138.0 -8566.0
YPEL5 7863.0 6331.0
YWHAB 8274.0 6101.0
YWHAZ 5165.0 5861.0
ZAP70 -10889.0 -10373.0
ZBP1 -11073.0 -10810.0
ZBTB16 -9729.0 5951.0
ZDHHC9 9626.0 9089.0
ZEB1 -2926.0 -6551.0
ZNRF1 8449.0 8470.0
ZNRF2 -598.0 2800.0



Membrane Trafficking

Membrane Trafficking
metric value
setSize 555
pMANOVA 5.94e-44
p.adjustMANOVA 2.02e-41
s.dist 0.399
s.low.CRP 0.194
s.high.CRP 0.349
p.low.CRP 5.33e-15
p.high.CRP 5.8e-45




Top 20 genes
Gene low CRP high CRP
F5 10084 10070
RAB13 10014 10088
VAMP7 10053 10044
RAB32 10006 10036
PLIN3 9856 10099
RAB31 9956 9895
GNS 9627 10060
YWHAG 9658 9994
PLA2G4A 9622 10024
GRB2 9631 9985
ITSN1 9969 9600
AGFG1 10023 9542
TBC1D2 9498 9999
SBF2 9757 9727
APP 9951 9504
SERPINA1 9571 9817
ARF4 9859 9444
YWHAE 9721 9563
SPTB 9958 9302
SORT1 10022 9241

Click HERE to show all gene set members

All member genes
low CRP high CRP
AAK1 -9118 -5763
ACBD3 7444 5845
ACTR10 8589 7569
ACTR1A -2833 8680
ACTR2 8743 7962
ACTR3 8622 7832
ADRB2 -11122 -7027
AGFG1 10023 9542
AGPAT3 6352 4771
AKT1 -4794 6231
AKT2 -8391 5504
AKT3 -9616 -10833
ALS2 3063 3862
ALS2CL -75 -10424
AMPH 6181 9351
ANK1 9797 8626
ANK3 3262 -7407
ANKRD27 -8124 4217
ANKRD28 -5795 -3898
AP1B1 8214 9804
AP1G1 -1796 5288
AP1G2 -3962 -4194
AP1M1 -3219 8558
AP1M2 4764 1487
AP1S1 9235 9982
AP1S2 6862 -6065
AP1S3 -5309 -4187
AP2A1 -3194 9104
AP2A2 3196 9217
AP2B1 -9145 2444
AP2M1 7742 9334
AP2S1 7422 8877
AP3B1 8649 9145
AP3S1 8709 7921
AP4B1 -7534 -3574
AP4E1 8480 5988
AP4M1 -6697 3666
AP4S1 3407 -6525
APP 9951 9504
ARCN1 4082 6402
AREG 4465 7165
ARF1 8465 9910
ARF3 5651 9049
ARF4 9859 9444
ARF5 5736 9180
ARF6 -2986 3785
ARFGAP1 -6136 2991
ARFGAP2 -8987 2096
ARFGAP3 -6040 5157
ARFIP2 -2956 -529
ARFRP1 -8821 -1241
ARL1 433 -3992
ARPC1A 8875 9605
ARPC2 5327 8212
ARPC3 8430 8946
ARPC4 4637 8915
ARPC5 9301 9174
ARRB1 -4581 4541
ARRB2 7827 9274
ASPSCR1 -3774 -3855
AVPR2 1919 -154
BET1 7030 -4395
BET1L -7832 -2582
BICD1 -8225 -5006
BICD2 8006 9959
BIN1 -9734 -10132
BLOC1S1 5994 9870
BLOC1S3 -9500 -3067
BLOC1S4 -9130 -2048
BLOC1S6 8956 6373
BNIP1 -3293 -5463
C2CD5 455 -7716
CALM1 -6645 1321
CAPZA1 8666 8511
CAPZA2 9698 8474
CAPZB 6100 8926
CBL 6620 8302
CCZ1 1286 5422
CCZ1B -932 2308
CD3D -9569 -10471
CD3G -9054 -10504
CD4 3147 -5743
CD55 9326 9842
CD59 4075 5772
CENPE -3467 886
CHM 3845 3159
CHML 5118 -3431
CHMP2A 8348 9510
CHMP2B 7436 5296
CHMP3 8980 8782
CHMP4A -1130 4862
CHMP4B 8338 9679
CHMP5 5879 5138
CHMP6 -6653 8292
CHMP7 -4593 -8038
CLINT1 -2323 4581
CLTA 8416 8998
CLTB -2857 8274
CLTC 9376 9720
CLTCL1 10011 9218
CNIH1 9316 7116
CNIH2 701 601
CNIH3 -8173 -6989
COG1 -10399 -10838
COG2 -1210 -5915
COG3 3891 -5333
COG4 -4813 2002
COG5 1617 -3368
COG6 1512 -6280
COG7 2191 6149
COG8 -2814 2839
COL7A1 3993 7683
COPA 7617 9591
COPB1 8213 7283
COPB2 8531 8034
COPE 365 8719
COPG1 2542 9195
COPG2 7905 8313
COPS2 8864 5037
COPS3 7364 5716
COPS4 1748 2715
COPS5 3882 5135
COPS6 -3920 4485
COPS7A 1707 8090
COPS7B -9179 -6481
COPS8 -1206 -8494
COPZ1 2549 5017
COPZ2 -9229 -9247
CPD 8389 9739
CSNK1D -10030 6117
CTSC -7528 5285
CTSZ 8972 9860
CTTN 7016 6516
CUX1 8954 9964
CYTH1 -11020 -10918
CYTH2 -5796 4527
CYTH3 -10332 -415
CYTH4 -3373 7558
DAB2 3735 9712
DCTN1 -5984 7873
DCTN2 8504 10012
DCTN3 325 7904
DCTN4 7967 9572
DCTN5 -7505 664
DCTN6 7871 7759
DENND1A 7886 8109
DENND1B -8424 -6268
DENND1C -8451 -2822
DENND2A -6339 -7276
DENND2C 3782 6386
DENND2D -11035 -10741
DENND3 7518 8410
DENND4A 78 -5656
DENND4B -3397 6083
DENND4C -3825 -6581
DENND5A 8536 7893
DENND5B 461 -5154
DENND6A -1706 1438
DENND6B 4313 3006
DNAJC6 6237 4061
DNASE2 6443 7266
DNM1 6883 3239
DNM2 -6816 8202
DNM3 7927 7198
DTNBP1 -4743 4629
DVL2 -10305 -7147
DYNC1H1 -8881 -2533
DYNC1I1 7141 2722
DYNC1I2 8160 8196
DYNC1LI1 7894 6997
DYNC1LI2 3494 5636
DYNLL1 6026 6499
DYNLL2 -6325 -225
EGF 9244 8355
EPN1 5120 9372
EPN2 -6096 -1735
EPS15 6185 4175
EPS15L1 -8354 6665
EREG -837 3226
EXOC1 7856 5981
EXOC2 -4967 -5340
EXOC3 -1111 6579
EXOC4 3396 7066
EXOC5 7495 3245
EXOC6 9570 9004
EXOC7 -5279 7572
EXOC8 -3430 2362
F5 10084 10070
F8 7498 7167
FCHO1 -3203 -76
FCHO2 8546 8432
FNBP1 -6673 3651
FNBP1L 9365 8493
FTH1 3543 5337
FTL 8704 9324
FZD4 -10858 -7985
GABARAP 8114 8339
GABARAPL2 9716 9166
GAK -5204 6408
GALNT1 7249 6590
GALNT2 8571 9697
GAPVD1 7396 7396
GBF1 -8933 1807
GCC1 -1592 4456
GCC2 2224 -8694
GDI1 2059 7275
GDI2 8206 7892
GGA1 -964 3744
GGA2 -8234 -3297
GGA3 509 5673
GJB6 -2646 5614
GJC1 -382 1106
GJC2 1419 2222
GJD3 8186 8611
GNS 9627 10060
GOLGA1 -8499 4971
GOLGA2 -878 8019
GOLGA4 -783 -4010
GOLGA5 6321 5485
GOLGB1 -242 -5768
GOLIM4 1630 7798
GORASP1 7651 6560
GOSR1 -4021 2971
GOSR2 -2437 1468
GPS1 -8718 1571
GRB2 9631 9985
GRK2 757 7818
GRK3 8742 6150
HBEGF 5089 5189
HGS -381 6840
HIP1 5859 9044
HIP1R -8953 -9087
HPS1 1337 7264
HPS4 -9603 -9743
HSPA8 -8286 -8908
IGF2R -1133 9240
IL7R -4956 -11140
ITSN1 9969 9600
ITSN2 7119 5093
KDELR1 9552 9681
KDELR2 8771 7531
KDELR3 2255 -3318
KIAA0319 -1650 3716
KIF11 -140 1030
KIF13B 1563 7357
KIF15 -4399 -3471
KIF16B 4416 3004
KIF18A -5118 -1862
KIF18B -3932 1641
KIF19 -10944 -8869
KIF1B 8577 8548
KIF1C 6981 8811
KIF20A 5368 4706
KIF20B -962 -8226
KIF21A -10337 -10254
KIF21B -10698 -135
KIF22 -10995 -11246
KIF23 8000 4957
KIF26A -155 -6527
KIF26B -10618 -9336
KIF27 5469 1812
KIF28P -7127 -4560
KIF2A 2515 -1329
KIF2C 2032 104
KIF3A -9378 -11000
KIF3B 3757 4323
KIF3C 7590 9010
KIF4A -1703 4331
KIF5A -7037 -7903
KIF5B 9540 8103
KIF5C -2924 -10718
KIF6 2741 806
KIF9 -1185 6392
KIFAP3 -8849 -4476
KIFC1 -3213 1241
KIFC2 -900 -938
KLC1 1745 7386
KLC2 -6674 -7322
KLC3 8390 7398
KLC4 -9223 -3527
LDLR 2463 6531
LDLRAP1 -668 -10304
LMAN1 -1255 -10522
LMAN2 2397 8522
LMAN2L 7675 6680
LNPEP -8634 -6784
LRP2 964 1845
M6PR -7566 -3638
MADD -10731 -7647
MAN1A1 4965 9297
MAN1A2 -1459 -993
MAN1C1 1436 -8761
MAN2A1 5542 -2948
MAN2A2 1864 8354
MAP1LC3B 7597 8663
MCFD2 7963 7485
MIA2 6640 5566
MIA3 3397 -6425
MON1A -8311 2318
MON1B 111 8054
MVB12A 6023 8501
MVB12B 2755 6228
MYH9 1879 8348
MYO1C 6395 2929
MYO5A 6789 7727
MYO6 -10507 -8938
NAA30 -5891 -7939
NAA35 -9061 -9861
NAA38 3081 9471
NAPA -2447 3305
NAPB -291 -2004
NAPG 7409 3591
NBAS 1380 1565
NECAP1 5273 2539
NECAP2 2916 4382
NEDD8 -156 8587
NSF 8895 9680
OCRL 7540 6631
OPTN -10447 -9518
PACSIN1 -11257 -11175
PACSIN2 8024 8785
PAFAH1B1 -336 6894
PAFAH1B2 7693 7761
PAFAH1B3 5824 4526
PICALM 9406 9673
PIK3C2A 1258 -5821
PIP5K1C -4447 6435
PLA2G4A 9622 10024
PLA2G6 -10753 -10993
PLIN3 9856 10099
POLG -10578 -1697
PPP6C 8559 6316
PPP6R1 -5320 7658
PPP6R3 3008 3925
PREB -1638 8142
PRKAB1 253 2895
PRKAB2 -3794 -7488
PRKAG1 1272 7037
PRKAG2 7892 7
PUM1 205 5294
RAB10 9303 9477
RAB11A 9786 8252
RAB11B -3172 6936
RAB12 5316 -2681
RAB13 10014 10088
RAB14 8215 7014
RAB18 9425 7287
RAB1A 9700 9407
RAB1B 5676 9455
RAB21 7222 6309
RAB27A 9164 8675
RAB27B -847 4689
RAB30 -7367 -8558
RAB31 9956 9895
RAB32 10006 10036
RAB33A -10854 -5029
RAB33B 8756 6897
RAB35 -6982 6352
RAB36 651 6588
RAB38 -10061 -3007
RAB39A 8587 6613
RAB39B -9791 -9905
RAB3A 7816 8757
RAB3GAP1 8630 5252
RAB3GAP2 4746 4797
RAB3IP 6917 2082
RAB41 -20 -4213
RAB43 4478 7506
RAB4A 9473 7027
RAB5A 8478 6815
RAB5B 3295 7820
RAB5C 7846 9422
RAB6A 8487 8616
RAB6B 6925 6712
RAB7A 8897 9367
RAB7B -7654 2220
RAB8A 540 5295
RAB8B 6227 7055
RAB9A 2889 5200
RAB9B -5682 -4620
RABEP1 -9142 -9849
RABEPK -1567 7092
RABGAP1 4102 2968
RABGEF1 8434 7639
RAC1 9052 9614
RACGAP1 3340 3770
RALA 7124 1151
RALGAPA2 9257 9433
RALGAPB -4707 -1027
REPS1 -7182 -2813
REPS2 7607 8723
RGP1 -2026 6446
RHOBTB3 -11228 -2363
RHOQ 9504 6692
RIC1 7981 6900
RIN1 5337 8446
RIN2 9710 8688
RINL -10942 -2982
RINT1 1211 -10524
RPS27A -3555 -7070
SAR1B 8795 5984
SBF1 -10462 -5210
SBF2 9757 9727
SCARB2 7273 5044
SCFD1 4551 3924
SCOC 7819 -5600
SEC13 2125 6861
SEC16A -2929 6748
SEC16B -1454 1213
SEC22A 374 -4424
SEC22B 8663 4943
SEC22C -2377 -1611
SEC23A 8776 6905
SEC23IP 5231 -574
SEC24A 8318 7788
SEC24B 1663 5398
SEC24C -9662 3561
SEC24D 8017 8795
SEC31A 1743 2474
SERPINA1 9571 9817
SFN -918 1127
SH3D19 1556 -4586
SH3GL1 4634 8807
SH3KBP1 4345 7311
SLC2A8 -10538 -9148
SNAP23 9586 8642
SNAP29 -1741 8902
SNAPIN 6576 8237
SNF8 2113 7859
SNX18 -1909 8980
SNX2 9104 7671
SNX5 -3170 -276
SNX9 -1545 1119
SORT1 10022 9241
SPTA1 9470 6216
SPTAN1 -10174 -8889
SPTB 9958 9302
SPTBN1 -6572 -6164
SPTBN2 -5447 -3871
SPTBN5 -7557 -461
SRC -6857 -7229
STAM 3046 2017
STAM2 8115 5912
STON1 3492 2681
STON2 2975 4565
STX10 9426 9350
STX16 5855 4189
STX17 -4480 -10772
STX18 566 6529
STX4 -7285 5736
STX5 3566 8258
STX6 7335 9578
STXBP3 9347 6785
SURF4 3781 8016
SYNJ1 5518 6949
SYNJ2 -6592 -7005
SYS1 -2469 2886
SYT1 6818 4381
SYT11 -10523 504
SYT2 -9931 3980
SYTL1 -9643 -7469
TBC1D1 4645 8191
TBC1D10A -11008 -7682
TBC1D10B 5776 9261
TBC1D10C -10716 -9378
TBC1D13 -8268 6866
TBC1D14 9253 9633
TBC1D15 8643 1524
TBC1D16 -2932 6664
TBC1D17 -8174 -5848
TBC1D2 9498 9999
TBC1D20 -6556 3818
TBC1D24 3703 4341
TBC1D25 -10571 1633
TBC1D3 498 -353
TBC1D4 -2031 -11212
TBC1D7 5088 7715
TBC1D8B 1187 1823
TF 1794 1244
TFG 8930 6725
TFRC 2181 1526
TGFA 7935 9686
TGOLN2 8606 9683
TJP1 -1182 -6918
TMED10 35 2168
TMED2 6426 6360
TMED3 -2098 4751
TMED7 9038 7918
TMED9 917 9007
TMEM115 31 6881
TMF1 5973 2223
TOR1A 7721 8423
TOR1B -8940 1768
TPD52 -6451 -8296
TPD52L1 -5873 -1009
TRAPPC1 5277 9110
TRAPPC10 -10478 -2812
TRAPPC11 8029 4815
TRAPPC12 4595 7519
TRAPPC13 4365 -4316
TRAPPC2 -8890 -5344
TRAPPC2L -350 -932
TRAPPC3 6827 7922
TRAPPC4 -7161 -2663
TRAPPC5 4081 6280
TRAPPC6A -7665 -10218
TRAPPC6B 6230 4019
TRAPPC8 7266 7046
TRAPPC9 921 7473
TRIP10 6573 1072
TRIP11 5087 -2116
TSC1 1502 -1612
TSC2 -4535 2859
TSG101 8461 7757
TXNDC5 6834 -3539
UBA52 -1875 3023
UBAP1 9074 9269
UBB 8251 6157
UBC -1915 5825
UBQLN1 5050 5353
UBQLN2 7704 5498
ULK1 1924 8728
USE1 1304 2460
USO1 6916 3905
USP6NL 8168 3185
VAMP2 -9677 -10779
VAMP3 9204 8284
VAMP4 7662 1445
VAMP7 10053 10044
VAMP8 2890 6767
VPS25 4731 8821
VPS28 388 6727
VPS36 2419 -7295
VPS37A 7815 6346
VPS37B -9566 6955
VPS37C 8342 8556
VPS45 6527 1884
VPS4A -5744 4778
VPS4B 5540 5495
VPS51 -8466 -1916
VPS52 -4410 -725
VPS53 -4323 2773
VPS54 9119 6993
VTA1 7807 5732
VTI1A -2998 7207
WASL 899 1391
YIPF6 7611 5809
YKT6 -3724 6818
YWHAB 8274 6101
YWHAE 9721 9563
YWHAG 9658 9994
YWHAH 9519 9189
YWHAQ -9021 -1643
YWHAZ 5165 5861
ZW10 5778 -752



Signal Transduction

Signal Transduction
metric value
setSize 1869
pMANOVA 1e-35
p.adjustMANOVA 2.74e-33
s.dist 0.198
s.low.CRP 0.0903
s.high.CRP 0.176
p.low.CRP 1.01e-10
p.high.CRP 2.34e-36




Top 20 genes
Gene low CRP high CRP
CSF2RA 10124 10140
PPARG 10111 10137
FZD5 10104 10128
S100A9 10110 10116
WASF1 10091 10132
GRB10 10103 10040
S100A8 10041 10093
PLB1 9997 10127
HRH2 10051 10037
XK 10092 9984
NUMB 10040 10006
CCR2 10062 9973
ATP6V0A1 9995 10010
GPER1 9928 10058
GNA15 9871 10112
EDNRB 9839 10139
PRKACA 9885 10068
SOCS3 9830 10110
LAMTOR1 9915 9919
RASGRP4 9926 9901

Click HERE to show all gene set members

All member genes
low CRP high CRP
A2M -7113.0 -9795.0
AAMP -5066.0 55.0
AATF -5754.0 6732.0
ABCA1 5566.0 7323.0
ABCG1 -7719.0 -6299.0
ABCG8 4588.0 3009.0
ABHD12 -10925.0 -3678.0
ABHD17A -10947.0 -3689.0
ABHD17B -1880.0 2621.0
ABHD17C -8389.0 2084.0
ABHD6 -8766.0 1990.0
ABI1 6692.0 7709.0
ABI2 -7512.0 -9823.0
ABL1 -6354.0 4467.0
ABR -802.0 8322.0
ACKR2 3285.0 1420.0
ACKR3 -11034.0 -2011.0
ACKR4 -7964.0 -4634.0
ACTA2 -1750.0 1138.0
ACTB 9310.0 9714.0
ACTG1 7674.0 9499.0
ACTR2 8743.0 7962.0
ACTR3 8622.0 7832.0
ACVR1B 9048.0 9961.0
ACVR1C 3243.0 -10245.0
ACVR2A -7204.0 -11003.0
ACVR2B -6617.0 -10642.0
ACVRL1 6791.0 9440.0
ADAM10 9314.0 9481.0
ADAM12 -3869.0 -4837.0
ADAM17 8058.0 9718.0
ADAP1 5460.0 8684.0
ADCY2 -4785.0 -910.0
ADCY3 8645.0 9780.0
ADCY4 4042.0 6126.0
ADCY5 -8988.0 -4426.0
ADCY6 -4846.0 651.0
ADCY7 -8603.0 2306.0
ADCY9 -3025.0 2535.0
ADGRE1 8802.0 9385.0
ADGRE2 6813.0 7659.0
ADGRE3 -5376.0 2276.0
ADGRE5 -10651.0 4158.0
ADM 8460.0 10101.0
ADM2 9195.0 4133.0
ADORA1 -7638.0 -9174.0
ADORA2A -4195.0 4298.0
ADORA2B 8620.0 9622.0
ADORA3 3488.0 6285.0
ADRA2A -416.0 4269.0
ADRB1 -9979.0 -3157.0
ADRB2 -11122.0 -7027.0
AGO1 2933.0 7911.0
AGO2 2783.0 4361.0
AGO3 5298.0 -2808.0
AGO4 9771.0 9580.0
AGRN -9794.0 -10649.0
AHCTF1 -1588.0 -103.0
AHCYL1 6114.0 7566.0
AKAP13 -5210.0 6504.0
AKR1C1 6158.0 -2806.0
AKR1C3 -11152.0 -8047.0
AKT1 -4794.0 6231.0
AKT1S1 8045.0 8241.0
AKT2 -8391.0 5504.0
AKT3 -9616.0 -10833.0
ALDH1A1 -8855.0 -11230.0
ALDH1A2 8646.0 9539.0
ALDH8A1 -5800.0 -6446.0
AMER1 -9251.0 -9464.0
AMH -2795.0 -4702.0
AMOT -11186.0 -9811.0
AMOTL1 -180.0 8087.0
ANGPT1 5647.0 1529.0
ANOS1 4787.0 4405.0
ANXA1 8162.0 8222.0
AP2A1 -3194.0 9104.0
AP2A2 3196.0 9217.0
AP2B1 -9145.0 2444.0
AP2M1 7742.0 9334.0
AP2S1 7422.0 8877.0
APBB1IP 9427.0 9201.0
APC 3083.0 3959.0
APH1A -3379.0 6321.0
APH1B 6306.0 6678.0
APOA2 2715.0 7325.0
APOE -5022.0 1771.0
APOM -106.0 1435.0
APP 9951.0 9504.0
AR 5214.0 4808.0
ARAF -5280.0 5379.0
ARAP1 5889.0 9116.0
ARAP2 -10793.0 -9493.0
ARAP3 8166.0 8842.0
AREG 4465.0 7165.0
ARF6 -2986.0 3785.0
ARHGAP1 -6103.0 7166.0
ARHGAP10 -7030.0 -6799.0
ARHGAP11A -974.0 3630.0
ARHGAP11B -8078.0 -4887.0
ARHGAP12 -5976.0 -5138.0
ARHGAP15 2604.0 228.0
ARHGAP17 -1419.0 -6569.0
ARHGAP18 9413.0 9465.0
ARHGAP19 7045.0 8536.0
ARHGAP21 6417.0 5320.0
ARHGAP22 4519.0 933.0
ARHGAP23 5840.0 6406.0
ARHGAP24 9246.0 7161.0
ARHGAP25 -10783.0 -521.0
ARHGAP26 7037.0 9592.0
ARHGAP27 -2132.0 7974.0
ARHGAP28 4513.0 2360.0
ARHGAP29 8334.0 8767.0
ARHGAP30 -4879.0 7113.0
ARHGAP31 6008.0 5748.0
ARHGAP32 6102.0 1745.0
ARHGAP33 -4849.0 -4707.0
ARHGAP35 -6993.0 1378.0
ARHGAP39 -5234.0 -7094.0
ARHGAP4 -6109.0 5209.0
ARHGAP42 -6566.0 -6230.0
ARHGAP44 2879.0 -666.0
ARHGAP5 3110.0 -10804.0
ARHGAP6 8128.0 8211.0
ARHGAP8 -11053.0 -10525.0
ARHGAP9 -1609.0 8482.0
ARHGDIA -2208.0 7927.0
ARHGDIB 7840.0 9497.0
ARHGEF1 -7319.0 -1527.0
ARHGEF10 -1806.0 -3987.0
ARHGEF10L 2548.0 -8075.0
ARHGEF11 9867.0 9882.0
ARHGEF12 -213.0 4295.0
ARHGEF17 6839.0 7119.0
ARHGEF18 -8526.0 -2076.0
ARHGEF19 -7958.0 -7166.0
ARHGEF2 1813.0 8144.0
ARHGEF25 -10967.0 -11041.0
ARHGEF26 -935.0 -4211.0
ARHGEF3 -10835.0 -9026.0
ARHGEF35 -2738.0 -4268.0
ARHGEF38 -5101.0 -2757.0
ARHGEF39 -9494.0 -9574.0
ARHGEF4 3629.0 -8573.0
ARHGEF40 8982.0 9475.0
ARHGEF5 -3592.0 -6792.0
ARHGEF6 4831.0 2908.0
ARHGEF7 -7925.0 1165.0
ARHGEF9 -10987.0 -10693.0
ARL2 -5078.0 2617.0
ARL4C -11241.0 -10094.0
ARPC1A 8875.0 9605.0
ARPC1B 9259.0 10026.0
ARPC2 5327.0 8212.0
ARPC3 8430.0 8946.0
ARPC4 4637.0 8915.0
ARPC5 9301.0 9174.0
ARRB1 -4581.0 4541.0
ARRB2 7827.0 9274.0
ASH2L 2845.0 6972.0
ATF1 7833.0 5463.0
ATF2 7002.0 164.0
ATN1 1214.0 594.0
ATP2A1 -4808.0 -3244.0
ATP2A2 8393.0 8341.0
ATP2A3 -9252.0 3112.0
ATP6AP1 2039.0 9790.0
ATP6V0A1 9995.0 10010.0
ATP6V0A2 -10623.0 -10379.0
ATP6V0B 8163.0 9396.0
ATP6V0C 9348.0 9734.0
ATP6V0D1 9444.0 9942.0
ATP6V0E1 8171.0 9289.0
ATP6V0E2 -8802.0 -11036.0
ATP6V1A 9857.0 9880.0
ATP6V1B2 9738.0 9281.0
ATP6V1C1 9888.0 8528.0
ATP6V1C2 2655.0 -3376.0
ATP6V1D 9600.0 9482.0
ATP6V1E1 8095.0 8397.0
ATP6V1E2 8322.0 4968.0
ATP6V1F 3461.0 6917.0
ATP6V1G1 5204.0 4277.0
ATP6V1G2 -4714.0 -10140.0
ATP6V1H 7942.0 8571.0
AURKB -4097.0 3408.0
AVPR1A 4473.0 3102.0
AVPR2 1919.0 -154.0
AXIN1 -10901.0 -2157.0
AXIN2 1014.0 -9374.0
AXL -11042.0 -10904.0
B4GALT1 -4177.0 7099.0
B9D2 8167.0 8798.0
BAD 1009.0 8765.0
BAG4 9013.0 9084.0
BAIAP2 2620.0 -682.0
BAMBI 8230.0 9181.0
BAX 4717.0 7227.0
BCL2 6148.0 -7816.0
BCL2L1 9743.0 8443.0
BCL2L11 8059.0 7998.0
BCL9 -2052.0 216.0
BCL9L -10522.0 -10404.0
BCO2 -9464.0 -5280.0
BCR -10286.0 261.0
BEX3 9172.0 7521.0
BIRC2 8079.0 3449.0
BIRC3 -2270.0 -11079.0
BIRC5 2725.0 4169.0
BMI1 -3862.0 -8689.0
BMPR1A -2831.0 -7715.0
BMPR2 2688.0 4304.0
BRAF 276.0 2552.0
BRAP 7133.0 5359.0
BRK1 5522.0 8298.0
BTK 7623.0 7870.0
BTRC -6845.0 -441.0
BUB1 5839.0 1925.0
BUB1B 3929.0 2104.0
BUB3 -7777.0 -10711.0
C3 -11179.0 -10489.0
C3AR1 8924.0 8181.0
C5 7727.0 2354.0
C5AR1 9359.0 9709.0
C5AR2 8198.0 8666.0
CAB39 9181.0 8435.0
CAB39L -4270.0 2711.0
CALCRL 8032.0 3879.0
CALM1 -6645.0 1321.0
CAMK2D -9328.0 -10857.0
CAMK2G -646.0 3153.0
CAMK4 246.0 -11195.0
CAMKK1 -184.0 7978.0
CAMKK2 8367.0 8768.0
CAMKMT 6048.0 -981.0
CARM1 9361.0 9442.0
CASP10 -2054.0 -1105.0
CASP2 -2223.0 235.0
CASP3 191.0 822.0
CASP8 -10359.0 -8523.0
CASP9 5303.0 9133.0
CASR -8364.0 -2828.0
CAV1 2492.0 1598.0
CAV2 7317.0 3827.0
CBFB 3639.0 2677.0
CBL 6620.0 8302.0
CBX2 -6781.0 -1304.0
CBX4 -7121.0 4998.0
CBX6 -2238.0 6533.0
CBX8 6588.0 5926.0
CBY1 -3580.0 -9677.0
CCDC88C -11013.0 -9133.0
CCL2 -10976.0 -11174.0
CCL28 -5861.0 -10884.0
CCL3 -407.0 -3940.0
CCL4 -11246.0 -6076.0
CCL5 -10668.0 -6900.0
CCNC 7860.0 -2135.0
CCND1 -4303.0 -5618.0
CCND3 -1611.0 8856.0
CCNE1 -8303.0 -11081.0
CCNK -3547.0 4337.0
CCNT1 -8231.0 -6368.0
CCNT2 770.0 -5045.0
CCR1 9641.0 9012.0
CCR10 2169.0 -2645.0
CCR2 10062.0 9973.0
CCR3 -6436.0 -10634.0
CCR4 -6598.0 -10476.0
CCR5 -9863.0 -5213.0
CCR6 -2172.0 -9131.0
CCR7 -276.0 -8948.0
CCR8 257.0 -9745.0
CCR9 6946.0 -2728.0
CCRL2 6084.0 8426.0
CD19 -2992.0 -2929.0
CD28 -2082.0 -11208.0
CD55 9326.0 9842.0
CD80 -2297.0 -7693.0
CD86 5511.0 -1419.0
CDC14A -2089.0 -10848.0
CDC14B 6650.0 -647.0
CDC20 -74.0 5136.0
CDC37 -4604.0 7006.0
CDC42 8498.0 7640.0
CDC42EP2 5485.0 6295.0
CDC42EP3 9829.0 8861.0
CDC73 5065.0 5233.0
CDCA8 -4836.0 412.0
CDH1 -10697.0 -8067.0
CDK1 4994.0 -360.0
CDK2 -5388.0 -2127.0
CDK4 -9596.0 -8845.0
CDK5 8395.0 9380.0
CDK5R1 -8396.0 3375.0
CDK8 -3688.0 1375.0
CDK9 -10657.0 5444.0
CDKN1A 3621.0 5190.0
CDKN1B -9926.0 -2672.0
CDKN2B 9493.0 9288.0
CDON -432.0 -9157.0
CENPA 3195.0 4228.0
CENPC -8807.0 -11097.0
CENPE -3467.0 886.0
CENPF -1889.0 3258.0
CENPH -3269.0 -8735.0
CENPI -2474.0 -2641.0
CENPK -2160.0 -9816.0
CENPL -10630.0 -8812.0
CENPM 1385.0 -7204.0
CENPN 4436.0 -1101.0
CENPO -10840.0 3129.0
CENPP -10848.0 -8710.0
CENPQ -911.0 -6285.0
CENPT -7579.0 -8354.0
CENPU -4192.0 -6597.0
CETP 7648.0 906.0
CFL1 5851.0 9242.0
CFLAR 7562.0 8281.0
CGN 7428.0 1125.0
CHD1 5133.0 -914.0
CHD3 -9446.0 -6383.0
CHD4 -8254.0 587.0
CHD8 -7984.0 4518.0
CHEK1 3978.0 -4829.0
CHN1 -1913.0 -7969.0
CHN2 5740.0 4836.0
CHRM5 -3179.0 -6573.0
CHUK 9198.0 7663.0
CILP -6679.0 -8991.0
CIT -7580.0 -2898.0
CKAP5 -6411.0 -2392.0
CLASP1 -9685.0 4156.0
CLASP2 2388.0 -1797.0
CLIP1 9515.0 8973.0
CLIP3 -4961.0 -10196.0
CLTA 8416.0 8998.0
CLTB -2857.0 8274.0
CLTC 9376.0 9720.0
CMKLR1 -11178.0 -3714.0
CNGB1 -1442.0 2608.0
CNKSR1 2877.0 -8713.0
CNKSR2 786.0 -5158.0
CNOT6L -9225.0 -9702.0
CNR1 1170.0 5303.0
CNR2 -8096.0 -5492.0
COL4A2 1717.0 838.0
COL4A3 -2340.0 -3206.0
COL4A4 611.0 -3693.0
COL6A1 5798.0 -5980.0
COL6A2 -10166.0 -7673.0
COL6A3 8421.0 3878.0
COL9A2 -10833.0 -5976.0
COL9A3 8252.0 4215.0
CPT1A 2381.0 6786.0
CPT1B -3067.0 -4000.0
CRABP2 -1649.0 -553.0
CREB1 4878.0 -3476.0
CREBBP -4951.0 6023.0
CRHBP 3873.0 4469.0
CRHR2 -7107.0 -2145.0
CRK 9657.0 9429.0
CRKL 1263.0 5754.0
CSF2RA 10124.0 10140.0
CSF2RB 7899.0 7940.0
CSK -5436.0 7707.0
CSNK1A1 8062.0 8483.0
CSNK1E -9947.0 -6531.0
CSNK1G2 -8130.0 4845.0
CSNK2A1 3192.0 8248.0
CSNK2A2 6050.0 7886.0
CSNK2B 1222.0 5287.0
CTBP1 -10319.0 2597.0
CTBP2 -8332.0 7583.0
CTNNA1 9646.0 10004.0
CTNNB1 3201.0 7613.0
CTNNBIP1 5853.0 8471.0
CTNND1 -4159.0 -7796.0
CTSD 9620.0 10120.0
CTTN 7016.0 6516.0
CUL1 -2085.0 -10951.0
CUL3 7151.0 7368.0
CUL5 7502.0 -2980.0
CX3CR1 -11009.0 -5262.0
CXCL1 4484.0 5698.0
CXCL10 5012.0 -11168.0
CXCL16 4033.0 9186.0
CXCL2 6689.0 5198.0
CXCL3 6020.0 4595.0
CXCL5 6317.0 3547.0
CXCL8 3332.0 -907.0
CXCL9 -3755.0 -11185.0
CXCR1 2112.0 7643.0
CXCR2 4038.0 6148.0
CXCR3 -9894.0 -10611.0
CXCR4 -3561.0 1966.0
CXCR5 -9360.0 -7361.0
CXCR6 -10552.0 -9466.0
CXXC4 -10472.0 -2258.0
CXXC5 -10302.0 -1836.0
CYBA -48.0 8901.0
CYBB 9900.0 8910.0
CYFIP1 9724.0 9912.0
CYFIP2 -10558.0 -4935.0
CYLD 2995.0 -11046.0
CYP4V2 -7850.0 -8445.0
CYSLTR1 2180.0 -8322.0
CYSLTR2 -2968.0 -8588.0
DAAM1 4929.0 3983.0
DAB2IP -8411.0 661.0
DACT1 7172.0 -2602.0
DAGLA -8692.0 -5866.0
DAGLB 3835.0 7615.0
DDX5 -8723.0 -7926.0
DEPDC1B 554.0 2004.0
DEPDC7 3901.0 -483.0
DERL2 4947.0 3337.0
DGKA 938.0 -9831.0
DGKD -9920.0 4546.0
DGKE -6514.0 -10998.0
DGKG 9648.0 7271.0
DGKH 4599.0 -5466.0
DGKK -10223.0 -7890.0
DGKQ -10016.0 -3011.0
DGKZ -9529.0 626.0
DHRS3 -11021.0 -9755.0
DHRS4 2830.0 4785.0
DHRS9 -1371.0 6282.0
DIAPH1 -9216.0 4270.0
DIAPH2 9067.0 9290.0
DIAPH3 6644.0 3344.0
DISP2 -4470.0 -6374.0
DLAT -430.0 -1295.0
DLC1 6410.0 9330.0
DLD 8131.0 7489.0
DLG1 -295.0 -8414.0
DLG2 -6786.0 -3319.0
DLG3 -10680.0 -10374.0
DLG4 9905.0 8876.0
DLGAP5 1242.0 3313.0
DLL1 -10099.0 -11006.0
DNAJB1 -8313.0 -1336.0
DNAL4 -697.0 5475.0
DNM1 6883.0 3239.0
DNM2 -6816.0 8202.0
DNM3 7927.0 7198.0
DOCK1 6941.0 8390.0
DOCK3 4726.0 -6915.0
DOCK7 3907.0 -3094.0
DOK1 5984.0 9447.0
DRAP1 -10374.0 264.0
DRD4 -10391.0 -7514.0
DSN1 -8825.0 -8996.0
DTX1 3485.0 -5093.0
DTX2 4632.0 8118.0
DTX4 1850.0 7305.0
DUSP1 4796.0 7997.0
DUSP10 -2707.0 823.0
DUSP16 -4867.0 -5937.0
DUSP2 -10179.0 -6646.0
DUSP3 9937.0 9647.0
DUSP4 -6630.0 -4192.0
DUSP5 -11052.0 -10044.0
DUSP6 7994.0 2589.0
DUSP7 -4748.0 387.0
DUSP8 -10417.0 -9519.0
DVL1 -1093.0 1894.0
DVL2 -10305.0 -7147.0
DVL3 -4437.0 8389.0
DYNC1H1 -8881.0 -2533.0
DYNC1I1 7141.0 2722.0
DYNC1I2 8160.0 8196.0
DYNC1LI1 7894.0 6997.0
DYNC1LI2 3494.0 5636.0
DYNC2H1 -8029.0 -5464.0
DYNLL1 6026.0 6499.0
DYNLL2 -6325.0 -225.0
E2F1 6782.0 6864.0
E2F3 4978.0 7309.0
E2F4 4494.0 7032.0
E2F5 -6261.0 -7227.0
EBAG9 -4619.0 -8811.0
ECE1 8272.0 8754.0
ECT2 7940.0 4902.0
EDN1 -4104.0 -9415.0
EDNRB 9839.0 10139.0
EED -4507.0 -6867.0
EEF2K -8518.0 -9729.0
EEPD1 6884.0 6469.0
EFCAB7 3252.0 -7082.0
EGF 9244.0 8355.0
EGR1 5173.0 2023.0
EGR2 2394.0 -4615.0
EGR3 -4151.0 868.0
EIF4B 4716.0 810.0
EIF4E 7143.0 4489.0
EIF4EBP1 6564.0 6276.0
EIF4G1 6261.0 9336.0
ELF3 1642.0 558.0
ELK1 -355.0 3195.0
ELMO1 4243.0 7282.0
ELMO2 -9506.0 6592.0
EP300 4311.0 7552.0
EPAS1 5959.0 8551.0
EPN1 5120.0 9372.0
EPOR 4687.0 8221.0
EPS15 6185.0 4175.0
EPS15L1 -8354.0 6665.0
ERBB2 -11251.0 -9287.0
ERBB3 3021.0 -1481.0
ERBIN 2164.0 -118.0
ERCC6L 2328.0 -1028.0
EREG -837.0 3226.0
ERLEC1 157.0 2344.0
ESR1 -6046.0 -8495.0
ESR2 -4206.0 -10115.0
ESRP2 -8071.0 -7011.0
ETV4 -2457.0 -2843.0
EVC -3360.0 2134.0
EVC2 -4717.0 -5141.0
EVL -10613.0 -11193.0
EZH2 -4248.0 -9643.0
F11R 8751.0 8489.0
F2R -10754.0 -3588.0
F2RL1 9505.0 8185.0
F2RL2 -5786.0 -419.0
F2RL3 3013.0 6077.0
FABP5 4135.0 6969.0
FADD -3611.0 7477.0
FAM13A 9663.0 5971.0
FAM13B -7815.0 -7976.0
FAS 6240.0 3017.0
FASLG -11268.0 -10430.0
FASN -3242.0 1451.0
FBXW7 -5277.0 -3657.0
FCER2 -951.0 -3382.0
FER 7034.0 -631.0
FES 9556.0 9967.0
FFAR2 6047.0 7588.0
FFAR3 2956.0 7295.0
FFAR4 6510.0 1912.0
FGD2 1340.0 6311.0
FGD3 -6445.0 5799.0
FGD4 9557.0 9414.0
FGF2 5967.0 3177.0
FGF22 -5885.0 -8493.0
FGF23 -3924.0 -7953.0
FGF7 158.0 -5338.0
FGF9 -8383.0 -6950.0
FGFBP2 -11279.0 -7748.0
FGFBP3 -9187.0 -6361.0
FGFR1 -8719.0 -822.0
FGFR2 -10068.0 -10229.0
FGFR4 -1760.0 -2742.0
FGFRL1 -10743.0 -8876.0
FKBP1A 9920.0 8990.0
FKBP4 3798.0 1107.0
FKBP5 9309.0 9774.0
FLNA -8145.0 4196.0
FLRT2 -2433.0 -3327.0
FLT1 3447.0 7527.0
FLT3 3904.0 8334.0
FLT3LG -415.0 -11122.0
FLT4 -5969.0 -7884.0
FMNL1 -7128.0 6527.0
FMNL2 -9177.0 -556.0
FMNL3 -11025.0 -9852.0
FN1 10003.0 6211.0
FNTA -147.0 -3320.0
FNTB 7121.0 6362.0
FOS 6663.0 6569.0
FOSB 339.0 1402.0
FOSL1 9842.0 8662.0
FOXO1 -4402.0 -9319.0
FOXO3 8202.0 9854.0
FOXO4 -615.0 8296.0
FOXO6 -9309.0 -1189.0
FPR1 9606.0 9929.0
FPR2 9572.0 9728.0
FPR3 -10790.0 -10402.0
FRAT1 8396.0 9480.0
FRAT2 9692.0 9464.0
FRK 23.0 486.0
FRS2 1765.0 -3137.0
FRS3 8041.0 7694.0
FSTL1 9009.0 8495.0
FSTL3 9845.0 9861.0
FURIN 8111.0 10053.0
FUZ -3700.0 2966.0
FYN -10878.0 -6729.0
FZD1 -468.0 5900.0
FZD2 6675.0 7410.0
FZD3 -374.0 -7373.0
FZD4 -10858.0 -7985.0
FZD5 10104.0 10128.0
FZD6 -304.0 -7933.0
FZD7 -3752.0 -6423.0
FZD8 -9255.0 -2577.0
GAB1 7926.0 5272.0
GAB2 7546.0 9347.0
GABBR1 3026.0 -4023.0
GABRB3 -5615.0 199.0
GABRG2 5684.0 -1211.0
GALNT3 -9370.0 4339.0
GALR1 488.0 329.0
GAS1 -10328.0 -5050.0
GAS8 7375.0 3661.0
GATA3 -10441.0 -11237.0
GATAD2A -6815.0 5314.0
GATAD2B -7514.0 2232.0
GDI1 2059.0 7275.0
GDI2 8206.0 7892.0
GFAP 8363.0 6022.0
GFRA2 -9183.0 -5056.0
GGA3 509.0 5673.0
GHRL -9172.0 -6917.0
GHSR -4838.0 -6948.0
GIPR -10351.0 -11192.0
GLI1 884.0 3509.0
GMIP 3917.0 9152.0
GNA11 5883.0 2815.0
GNA12 4000.0 3840.0
GNA13 5622.0 6234.0
GNA15 9871.0 10112.0
GNAI1 6562.0 2097.0
GNAI2 5861.0 9258.0
GNAI3 9178.0 7726.0
GNAL -9967.0 -1541.0
GNAO1 -10349.0 -6203.0
GNAQ 10007.0 8976.0
GNAS 8297.0 8173.0
GNAT1 3420.0 -509.0
GNAT2 6387.0 7579.0
GNAZ 2560.0 3945.0
GNB1 6908.0 9175.0
GNB2 6587.0 9064.0
GNB3 7806.0 -8406.0
GNB4 9340.0 6537.0
GNB5 6182.0 -475.0
GNG10 9939.0 9753.0
GNG11 8239.0 6403.0
GNG2 -10761.0 192.0
GNG3 4993.0 -794.0
GNG4 414.0 -2445.0
GNG5 8894.0 9403.0
GNG7 -2881.0 -4054.0
GNG8 4092.0 4604.0
GNGT2 -11227.0 -6988.0
GNRH1 -6034.0 -7752.0
GNRHR2 -9288.0 -5290.0
GOLGA7 4113.0 4351.0
GOPC -3131.0 -9251.0
GPAM -4790.0 -9067.0
GPBAR1 -4023.0 -5612.0
GPC1 -6229.0 -1709.0
GPC2 736.0 -5447.0
GPC4 -2862.0 -5115.0
GPER1 9928.0 10058.0
GPNMB -1281.0 108.0
GPR132 -9153.0 3707.0
GPR15 -3654.0 -9482.0
GPR150 -8487.0 -10216.0
GPR161 -2001.0 -5408.0
GPR18 -9943.0 -10723.0
GPR183 -8817.0 -11234.0
GPR20 -10975.0 -8440.0
GPR25 -10718.0 -6125.0
GPR27 9670.0 9900.0
GPR35 4904.0 8113.0
GPR37L1 4655.0 5864.0
GPR55 -8148.0 -9912.0
GPR65 -1776.0 5806.0
GPR68 -11172.0 -9471.0
GPR83 -4291.0 1630.0
GPR84 9267.0 9312.0
GPS2 -6562.0 2341.0
GPSM1 -6090.0 -4182.0
GPSM2 7359.0 4289.0
GPSM3 2700.0 7869.0
GRAP -5044.0 -10478.0
GRAP2 5425.0 4991.0
GRB10 10103.0 10040.0
GRB2 9631.0 9985.0
GREB1 -6806.0 -4928.0
GREM2 7483.0 -3242.0
GRIN2D 5414.0 6550.0
GRK2 757.0 7818.0
GRK3 8742.0 6150.0
GRK4 -2940.0 4755.0
GRK5 -2973.0 1597.0
GRK6 -758.0 7667.0
GRK7 -8005.0 -3035.0
GRM2 -9939.0 -9829.0
GRM6 -660.0 -1013.0
GRPR 6442.0 -363.0
GSK3A 5279.0 8683.0
GSK3B 6119.0 7526.0
GTF2A1 5229.0 2440.0
GTF2A2 8093.0 6862.0
GTF2F1 -3109.0 7342.0
GTF2F2 4728.0 6017.0
GUCA1B -5335.0 -2927.0
GUCY2D -11029.0 -251.0
GZMB -11253.0 -9712.0
H2AC20 -790.0 6112.0
H2AC6 8700.0 8169.0
H2AJ 8999.0 10117.0
H2AZ1 1779.0 7321.0
H2AZ2 -4042.0 2210.0
H2BC11 8424.0 8288.0
H2BC12 9066.0 9812.0
H2BC15 3036.0 6455.0
H2BC17 7882.0 7312.0
H2BC21 9852.0 9656.0
H2BC4 7156.0 7805.0
H2BC5 7596.0 8773.0
H2BC9 7965.0 4715.0
H2BU1 -6349.0 -3895.0
H3-3A 9297.0 9034.0
H3C15 5262.5 7402.5
HBEGF 5089.0 5189.0
HCAR1 -406.0 921.0
HCAR2 4709.0 3930.0
HCAR3 -1470.0 2234.0
HDAC1 -3835.0 3708.0
HDAC10 -489.0 4165.0
HDAC11 804.0 5759.0
HDAC2 8973.0 3999.0
HDAC3 1719.0 6319.0
HDAC4 9329.0 9546.0
HDAC5 3359.0 5480.0
HDAC6 -7766.0 -5123.0
HDAC7 4750.0 7247.0
HDAC8 3980.0 4023.0
HDAC9 6738.0 -815.0
HEBP1 8791.0 8531.0
HES1 -10141.0 -3420.0
HGF 9753.0 8929.0
HGS -381.0 6840.0
HHAT -6205.0 -8610.0
HIF1A 7330.0 7808.0
HNRNPA1 -2581.0 -3943.0
HNRNPF -334.0 5326.0
HNRNPH1 983.0 -9561.0
HNRNPM 2401.0 6565.0
HRAS -2248.0 -1932.0
HRH2 10051.0 10037.0
HRH4 -2897.0 -4883.0
HSD17B1 6487.0 3122.0
HSP90AA1 5309.0 410.0
HSP90AB1 2247.0 -6319.0
HSPB1 906.0 2714.0
HSPG2 -7219.0 -5674.0
HTR6 -288.0 -6092.0
HTR7 -774.0 -2330.0
ICMT -3792.0 2455.0
ICOS 1302.0 -10781.0
ID1 -4474.0 7580.0
ID2 -11205.0 -1959.0
ID3 -8695.0 -7195.0
IER3 8774.0 7369.0
IFT122 3729.0 5952.0
IFT140 -1268.0 -3851.0
IFT172 -8733.0 -9399.0
IFT52 -1672.0 495.0
IFT57 -4411.0 -53.0
IFT88 -2178.0 -167.0
IGF1R 4264.0 6294.0
IKBKB -5276.0 -2118.0
IKBKG -3058.0 7903.0
IKZF1 -9076.0 -2554.0
IL1RAP 3294.0 7375.0
IL1RL1 8858.0 -1567.0
IL2RA 1007.0 -8826.0
IL2RB -11256.0 -10415.0
IL2RG -10931.0 -9531.0
IL33 -438.0 931.0
IL3RA -10088.0 -10505.0
IL5RA -8551.0 -10227.0
IL6R 9360.0 8189.0
IL6ST 7914.0 1855.0
INCENP -9437.0 323.0
INHBA 6428.0 2006.0
INPP5B -5371.0 -4931.0
INSL3 7991.0 6252.0
INSR 9014.0 8953.0
INTU -3002.0 -3430.0
IQCE 8341.0 9603.0
IQGAP1 7310.0 9366.0
IQGAP2 6198.0 7948.0
IQGAP3 3938.0 3957.0
IRAK1 2444.0 7601.0
IRS1 6140.0 8.0
IRS2 8141.0 9618.0
ITCH -2889.0 3792.0
ITGA2 8852.0 -28.0
ITGA2B 9720.0 9409.0
ITGA3 -6696.0 -9714.0
ITGAV 7467.0 6188.0
ITGB1 3360.0 -108.0
ITGB3 9450.0 8690.0
ITGB3BP -458.0 -8029.0
ITPR1 -5546.0 -5368.0
ITPR2 6833.0 6418.0
ITPR3 -8438.0 -9066.0
ITSN1 9969.0 9600.0
JAG1 9550.0 8956.0
JAG2 -10015.0 -8085.0
JAK1 -10669.0 -4353.0
JAK2 7618.0 374.0
JAK3 8703.0 8585.0
JUN 2838.0 4810.0
JUNB 5989.0 7459.0
JUND 69.0 2516.0
JUP -4305.0 -4960.0
KALRN 999.0 -4389.0
KANK1 3022.0 -7617.0
KAT2A -6742.0 -10405.0
KAT2B 116.0 -1532.0
KAT5 -7070.0 4899.0
KBTBD7 3626.0 6975.0
KCTD6 4870.0 5068.0
KDM1A -6245.0 -6064.0
KDM1B 6297.0 4922.0
KDM3A -9927.0 -11194.0
KDM4A -5855.0 4280.0
KDM4B 6479.0 8890.0
KDM4C -9638.0 -6288.0
KEL -294.0 7064.0
KHDRBS1 3041.0 3910.0
KHDRBS2 875.0 -4956.0
KIDINS220 6851.0 7729.0
KIF14 1714.0 3512.0
KIF18A -5118.0 -1862.0
KIF2A 2515.0 -1329.0
KIF2C 2032.0 104.0
KIF3A -9378.0 -11000.0
KIF5A -7037.0 -7903.0
KIF5B 9540.0 8103.0
KIF7 -10924.0 -6861.0
KISS1R 6584.0 -4556.0
KIT -10872.0 -8011.0
KL 9145.0 9846.0
KLC1 1745.0 7386.0
KLC2 -6674.0 -7322.0
KLC3 8390.0 7398.0
KLC4 -9223.0 -3527.0
KLHL12 4669.0 8766.0
KLK2 7104.0 1104.0
KMT2D -2369.0 5062.0
KNL1 -1431.0 -91.0
KNTC1 -224.0 -8592.0
KPNA2 -7397.0 -3307.0
KRAS 3789.0 4070.0
KREMEN1 8950.0 9970.0
KREMEN2 -6004.0 4016.0
KSR1 326.0 5540.0
KSR2 -3767.0 -1942.0
KTN1 7536.0 1922.0
LAMA1 1937.0 -1809.0
LAMA2 -10568.0 -6239.0
LAMA4 -5156.0 597.0
LAMA5 565.0 -2964.0
LAMB1 2797.0 7716.0
LAMB2 3126.0 -317.0
LAMB3 4293.0 8192.0
LAMC1 9628.0 10118.0
LAMC3 1290.0 -4227.0
LAMTOR1 9915.0 9919.0
LAMTOR2 3802.0 9208.0
LAMTOR3 9012.0 7104.0
LAMTOR4 -3016.0 6293.0
LAMTOR5 8466.0 9035.0
LAT -9843.0 -10628.0
LATS1 5074.0 -2853.0
LATS2 1342.0 8964.0
LCK -10358.0 -10719.0
LDLR 2463.0 6531.0
LEF1 4722.0 -10841.0
LEO1 6728.0 -1045.0
LEPR 7286.0 6904.0
LFNG -9497.0 -3283.0
LGR4 3548.0 2777.0
LGR6 -11188.0 -9867.0
LIMK1 -2747.0 6617.0
LIMK2 8349.0 8299.0
LIN7B -5596.0 -560.0
LINC01139 995.0 -4888.0
LPAR1 8087.0 4987.0
LPAR2 141.0 7467.0
LPAR3 355.0 -8005.0
LPAR5 -10903.0 -6736.0
LPAR6 7225.0 -7603.0
LPL -2018.0 4002.0
LRIG1 -3916.0 -10887.0
LRP1 9226.0 9878.0
LRP10 -513.0 8129.0
LRP12 6551.0 7062.0
LRP2 964.0 1845.0
LRP5 5683.0 4611.0
LRP6 3999.0 -1401.0
LRP8 -1100.0 5967.0
LRRC7 -623.0 -1369.0
LRRK2 9228.0 7329.0
LTB4R 8063.0 9751.0
LTB4R2 -3129.0 2954.0
LYL1 8718.0 8646.0
LYN 7575.0 8379.0
LYPLA1 9192.0 8174.0
MAD1L1 -7936.0 -748.0
MAD2L1 -1797.0 -8340.0
MADD -10731.0 -7647.0
MAF1 2263.0 6749.0
MAGED1 -10798.0 -11115.0
MAML1 -81.0 7084.0
MAML2 3788.0 -1483.0
MAML3 9463.0 9534.0
MAMLD1 -532.0 -6686.0
MAP2K1 9163.0 9879.0
MAP2K2 185.0 8452.0
MAP2K5 3641.0 4561.0
MAP3K11 6025.0 8985.0
MAP3K7 1546.0 4274.0
MAPK1 1052.0 9260.0
MAPK11 7257.0 1843.0
MAPK12 1925.0 -1837.0
MAPK13 -8511.0 5595.0
MAPK14 9907.0 9606.0
MAPK3 8931.0 9626.0
MAPK6 8801.0 8000.0
MAPK7 -10125.0 5069.0
MAPK8 -1061.0 -9914.0
MAPKAP1 2536.0 5925.0
MAPKAPK2 -10572.0 6892.0
MAPKAPK3 7493.0 9250.0
MAPKAPK5 121.0 -9279.0
MAPRE1 8382.0 7653.0
MARK3 9434.0 9486.0
MATK -11258.0 -9057.0
MBD3 -247.0 1576.0
MC1R -10590.0 -8703.0
MCF2 -3103.0 3888.0
MCF2L 1063.0 -9438.0
MCHR1 -3531.0 -4084.0
MDK -1527.0 -3362.0
MDM2 7204.0 3892.0
MECOM -10094.0 4468.0
MED1 -2730.0 -1762.0
MEF2A 9000.0 8162.0
MEF2C 6943.0 -2868.0
MEF2D -9268.0 3542.0
MEMO1 9615.0 8983.0
MEN1 -8589.0 -4575.0
METAP1 119.0 -6911.0
METAP2 4623.0 -1070.0
MFNG -7860.0 -990.0
MGLL 8873.0 7773.0
MIB1 3219.0 -3926.0
MIB2 -10461.0 -7734.0
MIR25 -9988.0 -7465.0
MIS12 -6139.0 -10061.0
MKNK1 8618.0 8672.0
MKRN1 9789.0 8565.0
MKS1 -8185.0 -8681.0
MLST8 -3991.0 2978.0
MMP7 5686.0 3331.0
MMP9 9225.0 9700.0
MOB1A 9302.0 8383.0
MOB1B 9745.0 5254.0
MOV10 -10256.0 -10510.0
MRAS -10710.0 298.0
MRTFA 7793.0 9266.0
MST1 -4917.0 3393.0
MST1R -6825.0 -2819.0
MT-RNR2 -373.0 3642.0
MTA1 -550.0 -1521.0
MTA2 -10115.0 863.0
MTA3 -7862.0 -7132.0
MTMR4 -1239.0 4307.0
MTOR -10419.0 -3248.0
MUC20 -2625.0 -6328.0
MXD4 -10907.0 -6100.0
MYB 6506.0 -1852.0
MYC 8429.0 -2186.0
MYD88 8651.0 8344.0
MYH10 -7101.0 3044.0
MYH11 1903.0 -4778.0
MYH9 1879.0 8348.0
MYL12B -2612.0 6816.0
MYL6 6786.0 9643.0
MYL9 9640.0 7741.0
MYLIP -4440.0 -1671.0
MYLK 8091.0 6661.0
MYO7A 9906.0 9829.0
MYO9A -6991.0 -7861.0
MYO9B 513.0 8592.0
NAB1 7194.0 -445.0
NAB2 -9246.0 -7768.0
NAPEPLD 3207.0 -8341.0
NBEA 3872.0 -2283.0
NCAM1 -11155.0 -5990.0
NCBP1 1766.0 -6055.0
NCBP2 3719.0 -10143.0
NCF1 8576.0 7083.0
NCF2 9748.0 9694.0
NCF4 9697.0 9856.0
NCK1 -9250.0 -9113.0
NCK2 4176.0 5976.0
NCKAP1 6871.0 8168.0
NCKAP1L 3966.0 9566.0
NCKIPSD 957.0 1858.0
NCOA1 -1753.0 6268.0
NCOA2 -4443.0 3788.0
NCOA3 3630.0 4256.0
NCOR1 3309.0 7790.0
NCOR2 4843.0 9646.0
NCSTN 9503.0 9869.0
NDC80 -4016.0 -9035.0
NDE1 2098.0 4048.0
NDEL1 5664.0 8515.0
NEDD4 -884.0 7132.0
NEDD4L 8246.0 8260.0
NEDD8 -156.0 8587.0
NEFL 2738.0 -8726.0
NELFB -8446.0 5056.0
NET1 -5084.0 -7146.0
NEURL1 -11174.0 -6488.0
NEURL1B -9540.0 2352.0
NF1 -1234.0 4267.0
NF2 -9157.0 -819.0
NFATC1 -9648.0 -4795.0
NFKB1 7857.0 6377.0
NFKBIA 6855.0 7374.0
NGFR -8252.0 -253.0
NLK 3383.0 3944.0
NLN 9350.0 5207.0
NMB -819.0 -186.0
NMT1 -372.0 6750.0
NMT2 -9645.0 -11173.0
NMUR1 -11233.0 -8303.0
NOG -5498.0 -10961.0
NOS3 5934.0 -5046.0
NOTCH1 -6446.0 6708.0
NOTCH2 4412.0 6414.0
NOTCH3 -744.0 9587.0
NOTCH4 -10586.0 1602.0
NOXA1 -2600.0 -5589.0
NPFFR1 7739.0 1031.0
NPHP4 1332.0 2912.0
NR1H2 4003.0 8448.0
NR1H3 -8939.0 2196.0
NR3C1 -5002.0 2698.0
NR4A1 -7773.0 -6467.0
NRAS 7321.0 4878.0
NRG1 8713.0 914.0
NRG4 1196.0 -3291.0
NRIP1 4155.0 5430.0
NRP1 -9711.0 -5356.0
NRP2 -1597.0 -4081.0
NSL1 6939.0 5555.0
NSMAF 2937.0 116.0
NTRK1 -3499.0 -8157.0
NTSR1 8769.0 9862.0
NUDC -2705.0 2609.0
NUF2 -4390.0 -3313.0
NUMB 10040.0 10006.0
NUP107 -4463.0 -10317.0
NUP133 -4339.0 -4616.0
NUP160 -2518.0 -10020.0
NUP37 3188.0 3613.0
NUP43 -55.0 -10161.0
NUP85 1119.0 -2732.0
NUP98 208.0 4310.0
OBSCN -1198.0 -8212.0
OCRL 7540.0 6631.0
OFD1 -7870.0 -10733.0
OMG 8768.0 8562.0
OPHN1 -2899.0 180.0
OPN3 6364.0 6274.0
OPRD1 -4129.0 -3347.0
OPRL1 6785.0 8660.0
OPRM1 4355.0 1404.0
OR10A6 4492.0 -3575.0
OR10AC1 1316.0 -465.0
OR10G3 2769.0 3768.0
OR10H5 -2609.0 -1196.0
OR14J1 -2959.0 -3935.0
OR14L1P 5747.0 -1078.0
OR1A1 1727.0 -4379.0
OR1D2 4461.0 28.0
OR1I1 5038.0 -669.0
OR1M1 -4370.0 -1044.0
OR2A1 -1759.0 -7150.0
OR2A5 -4138.0 -2195.0
OR2A7 475.0 -8792.0
OR2AT4 4350.0 -1996.0
OR2B11 6656.0 5212.0
OR2C3 2540.0 3670.0
OR2G6 7961.0 -710.0
OR2H2 6582.0 337.0
OR2I1P -675.0 -9645.0
OR2L2 3611.0 6098.0
OR2M3 5707.0 44.0
OR2M4 7869.0 -2427.0
OR2T33 6228.0 5339.0
OR2V2 7984.0 1006.0
OR2W3 9815.0 7826.0
OR4D1 -7657.0 -9944.0
OR4D9 -3439.0 1042.0
OR4E1 -1848.0 -2391.0
OR4K17 2139.0 -1182.0
OR51L1 2799.0 2674.0
OR52A1 -4246.0 4552.0
OR52K1 8195.0 6076.0
OR52N4 -5918.0 -9268.0
OR56A1 3949.0 0.0
OR5A1 -1418.0 -749.0
OR5A2 -3642.0 -5573.0
OR5AN1 -557.0 -4236.0
OR5AS1 -6464.0 -4749.0
OR5AU1 -1690.0 2917.0
OR6C75 7479.0 3084.0
OR6Y1 -1041.0 -3138.0
OR7A17 -6635.0 -1026.0
OR7A5 -4946.0 -762.0
OR7C1 1931.0 2656.0
OR7D2 -629.0 -1376.0
OR8A1 7043.0 1569.0
OS9 8889.0 9708.0
OTUD3 -6891.0 -9799.0
OTUD7B -11017.0 -9453.0
OTULIN 3200.0 -288.0
OXER1 4959.0 7690.0
OXTR -3961.0 1222.0
P2RY1 800.0 9467.0
P2RY10 -10031.0 -10839.0
P2RY11 -10046.0 -8647.0
P2RY12 5843.0 4889.0
P2RY13 9100.0 7999.0
P2RY14 -9835.0 -11100.0
P2RY2 6847.0 6014.0
P2RY6 -9778.0 -8963.0
P4HB 6474.0 9641.0
PAFAH1B1 -336.0 6894.0
PAG1 2942.0 5215.0
PAK1 9711.0 7682.0
PAK2 9019.0 8433.0
PAK3 -1134.0 -4249.0
PAQR3 -1798.0 -2543.0
PARD3 7352.0 7983.0
PARD6A -1188.0 1317.0
PARP1 -10438.0 -8545.0
PBX1 1959.0 6243.0
PCP2 -4638.0 1512.0
PCSK5 6394.0 4664.0
PCSK6 9717.0 9061.0
PDE11A 4522.0 3010.0
PDE1B 3331.0 7142.0
PDE2A -4524.0 1659.0
PDE3A 7578.0 6655.0
PDE3B -7149.0 -10938.0
PDE4A -8856.0 2962.0
PDE4B 2046.0 -7803.0
PDE4C 8368.0 5193.0
PDE4D -8377.0 3702.0
PDE6A 5612.0 -5655.0
PDE6B -9215.0 -10116.0
PDE6D 2041.0 6166.0
PDE6G -9811.0 4921.0
PDE7A -6106.0 -10178.0
PDE7B -649.0 -1193.0
PDE8A -7173.0 -4046.0
PDE8B -9837.0 -2013.0
PDGFA 6115.0 5392.0
PDGFB -4645.0 -8897.0
PDGFC 1293.0 6752.0
PDGFD -11225.0 -8372.0
PDGFRA 2481.0 6753.0
PDGFRB -11134.0 -5992.0
PDHA1 -4916.0 117.0
PDHB 6533.0 3960.0
PDHX 7203.0 3502.0
PDK1 8540.0 1574.0
PDK2 -9124.0 -4346.0
PDK3 1125.0 4803.0
PDK4 7304.0 6115.0
PDPK1 2392.0 7816.0
PEA15 -3644.0 -5134.0
PEBP1 -8004.0 -10339.0
PELP1 -7852.0 -9443.0
PF4 6097.0 6609.0
PFN1 -5663.0 7801.0
PFN2 5971.0 -5360.0
PGF -8745.0 -1426.0
PHB -4398.0 564.0
PHC1 -5034.0 -8115.0
PHC2 8426.0 9918.0
PHC3 -3083.0 -7777.0
PHLPP1 -8074.0 6183.0
PHLPP2 -10345.0 -10633.0
PIK3AP1 6149.0 8581.0
PIK3C3 6605.0 573.0
PIK3CA 6889.0 4182.0
PIK3CB 9838.0 9248.0
PIK3CD 82.0 7288.0
PIK3CG -9742.0 5545.0
PIK3R1 -7197.0 -8942.0
PIK3R2 2459.0 5820.0
PIK3R3 -11107.0 -8159.0
PIK3R4 -267.0 -2209.0
PIK3R5 -9700.0 3911.0
PIK3R6 8267.0 7206.0
PIN1 -9660.0 3728.0
PIP4K2A -8599.0 2837.0
PIP4K2B -7642.0 -3179.0
PIP4K2C -10764.0 -5694.0
PIP5K1A 6224.0 6407.0
PIP5K1B 5094.0 7192.0
PIP5K1C -4447.0 6435.0
PKN1 -10294.0 5192.0
PKN2 6764.0 -3104.0
PKN3 -6719.0 -1067.0
PLA2G4A 9622.0 10024.0
PLAT 6118.0 -4882.0
PLB1 9997.0 10127.0
PLCB1 1989.0 1657.0
PLCB2 2249.0 5858.0
PLCB3 8806.0 9909.0
PLCG1 -6360.0 -11043.0
PLCG2 -4618.0 6826.0
PLEKHG2 6397.0 8532.0
PLEKHG5 142.0 -10045.0
PLG 1277.0 -2998.0
PLIN1 -6629.0 -678.0
PLK1 -235.0 4265.0
PLPPR2 9355.0 9299.0
PLPPR3 6234.0 396.0
PLTP 1710.0 9224.0
PLXNB1 4183.0 6269.0
PLXND1 6191.0 8701.0
PMEPA1 -1501.0 -4407.0
PMF1 3040.0 4375.0
PML -6449.0 -6720.0
PNOC -2675.0 -3969.0
POFUT1 -435.0 3675.0
POGLUT1 -5394.0 -7044.0
POLR2A -8726.0 2901.0
POLR2B -1034.0 188.0
POLR2C -2183.0 3527.0
POLR2D 3401.0 -4083.0
POLR2E 6766.0 8343.0
POLR2F -2307.0 6746.0
POLR2G -5778.0 6576.0
POLR2H 653.0 -2264.0
POLR2I -2123.0 2695.0
POLR2J 4448.0 7822.0
POLR2K 1881.0 -1885.0
POLR2L 126.0 7246.0
POMC 1489.0 3391.0
PORCN -9834.0 -6886.0
POU2F1 -609.0 2898.0
PPARD -2381.0 -5446.0
PPARG 10111.0 10137.0
PPBP 7528.0 6376.0
PPEF1 4819.0 -3021.0
PPID 7689.0 3714.0
PPM1A 8485.0 8676.0
PPP1CA -5695.0 6595.0
PPP1CB 8657.0 6666.0
PPP1CC 9200.0 4868.0
PPP1R12A 5601.0 6368.0
PPP1R12B -4326.0 4036.0
PPP1R14A 7499.0 7460.0
PPP1R15A 6448.0 5992.0
PPP2CA 8810.0 8328.0
PPP2CB 8482.0 7631.0
PPP2R1A -3087.0 6994.0
PPP2R1B 2503.0 437.0
PPP2R5A -903.0 6957.0
PPP2R5B 5288.0 7952.0
PPP2R5C -10420.0 -7112.0
PPP2R5D -6508.0 4985.0
PPP2R5E 715.0 540.0
PPP3CA 6208.0 7300.0
PPP3CB 8057.0 6833.0
PPP3CC -10915.0 -10544.0
PPP3R1 8998.0 8570.0
PPP5C -9397.0 -2360.0
PRC1 -5431.0 2601.0
PRDM4 -9286.0 -5366.0
PREX1 -6574.0 8855.0
PRICKLE1 6870.0 800.0
PRKAA1 1212.0 2036.0
PRKAB1 253.0 2895.0
PRKAB2 -3794.0 -7488.0
PRKACA 9885.0 10068.0
PRKACB -9852.0 -10936.0
PRKAG1 1272.0 7037.0
PRKAG2 7892.0 7.0
PRKAR1A 8455.0 9570.0
PRKAR1B 8879.0 7874.0
PRKAR2A 3755.0 7093.0
PRKAR2B 7943.0 7189.0
PRKCA 2473.0 1229.0
PRKCB 5395.0 8378.0
PRKCD 9393.0 9642.0
PRKCE -10383.0 -2720.0
PRKCH -11170.0 -10819.0
PRKCI 6134.0 -2289.0
PRKCQ -10709.0 -10890.0
PRKCZ -10855.0 -7708.0
PRKG1 8854.0 5968.0
PRKG2 -7602.0 -7604.0
PRKX -5579.0 -9049.0
PRMT1 -8095.0 -6184.0
PROK2 8056.0 9295.0
PRR5 -11173.0 -8620.0
PSAP 7519.0 7770.0
PSEN1 7889.0 8878.0
PSEN2 -5169.0 -5867.0
PSENEN 2692.0 7551.0
PSMA1 8278.0 7406.0
PSMA2 5830.0 5666.0
PSMA3 4646.0 -7621.0
PSMA4 3950.0 -1036.0
PSMA5 -2119.0 -3983.0
PSMA6 6893.0 5865.0
PSMA7 3550.0 8554.0
PSMB1 3915.0 4224.0
PSMB10 -7878.0 -1272.0
PSMB2 2664.0 4928.0
PSMB3 4971.0 8382.0
PSMB4 -3175.0 4911.0
PSMB5 6561.0 9138.0
PSMB6 1312.0 8784.0
PSMB7 8034.0 9051.0
PSMB8 -4481.0 75.0
PSMB9 -9105.0 -10433.0
PSMC1 6759.0 7782.0
PSMC2 -2524.0 4517.0
PSMC3 -4971.0 4984.0
PSMC4 -10757.0 -336.0
PSMC5 -3424.0 2764.0
PSMC6 8812.0 6000.0
PSMD1 7679.0 7587.0
PSMD10 2067.0 2450.0
PSMD11 6914.0 6824.0
PSMD12 9011.0 5710.0
PSMD13 3157.0 7205.0
PSMD14 2891.0 3041.0
PSMD2 4352.0 8396.0
PSMD3 -2243.0 6367.0
PSMD4 6858.0 9449.0
PSMD5 2770.0 4781.0
PSMD6 8841.0 8304.0
PSMD7 6534.0 6147.0
PSMD8 739.0 7117.0
PSMD9 3580.0 9001.0
PSME1 -7256.0 -7913.0
PSME2 -5548.0 -10355.0
PSME3 9120.0 8239.0
PSME4 -5205.0 -3127.0
PSMF1 6709.0 6770.0
PSPN 6438.0 2245.0
PTAFR 9791.0 9983.0
PTBP1 -3207.0 2729.0
PTCH1 -11110.0 -8984.0
PTCH2 -2301.0 -4344.0
PTCRA 8101.0 8187.0
PTEN 9191.0 8752.0
PTENP1 -2788.0 -4938.0
PTGDR -11236.0 -8923.0
PTGDR2 -10713.0 -10663.0
PTGER2 -1945.0 2934.0
PTGER3 8710.0 1304.0
PTGER4 -10608.0 -8098.0
PTGES3 8385.0 2175.0
PTGFR 9467.0 8601.0
PTGIR -8467.0 -6760.0
PTK2 7786.0 3481.0
PTK2B 2270.0 9537.0
PTK6 6593.0 5974.0
PTPN1 -8327.0 7695.0
PTPN11 4691.0 6614.0
PTPN12 7921.0 9275.0
PTPN18 -1694.0 8540.0
PTPN2 7776.0 8909.0
PTPN3 -742.0 873.0
PTPN6 -691.0 7862.0
PTPN7 -10607.0 -6009.0
PTPRA -10794.0 3851.0
PTPRJ 4613.0 9148.0
PTPRK -5308.0 -7004.0
PTPRO 4554.0 2333.0
PTPRS -11226.0 -9306.0
PTPRU -4519.0 -979.0
PXN -5634.0 8031.0
PYGO2 -9829.0 -8073.0
QRFP -3657.0 3536.0
RAB4A 9473.0 7027.0
RAB4B -7808.0 7089.0
RAB6A 8487.0 8616.0
RAC1 9052.0 9614.0
RAC2 -7677.0 6828.0
RAC3 -4395.0 -1033.0
RACGAP1 3340.0 3770.0
RACK1 293.0 1632.0
RAD21 3724.0 1987.0
RAF1 8477.0 8327.0
RAG1 -10678.0 -8094.0
RALA 7124.0 1151.0
RALB 9150.0 8771.0
RALBP1 6092.0 7629.0
RALGDS -11080.0 -10024.0
RAMP1 -10784.0 851.0
RANBP10 2888.0 3405.0
RANBP2 4453.0 -2222.0
RANBP9 3568.0 6133.0
RANGAP1 -10259.0 -9220.0
RAP1A 8688.0 6973.0
RAP1B -2703.0 4941.0
RAPGEF1 -10851.0 -864.0
RAPGEF2 6349.0 7882.0
RAPGEF3 1224.0 -2066.0
RARA -356.0 8119.0
RARG -1415.0 -3798.0
RASA1 4308.0 2428.0
RASA2 -7280.0 -1511.0
RASA3 -10301.0 -9692.0
RASA4 -10075.0 -10354.0
RASAL1 1927.0 -1545.0
RASAL2 2199.0 20.0
RASAL3 -10844.0 -9650.0
RASGEF1A -10612.0 1500.0
RASGRF1 -5249.0 -2699.0
RASGRF2 -4591.0 -10584.0
RASGRP1 -9849.0 -11029.0
RASGRP2 -7479.0 -7190.0
RASGRP3 -4981.0 -8320.0
RASGRP4 9926.0 9901.0
RBBP4 4016.0 -1020.0
RBBP5 4931.0 173.0
RBBP7 -10846.0 -9848.0
RBCK1 -4700.0 4686.0
RBFOX2 -7423.0 -5065.0
RBL1 -6879.0 -8773.0
RBPJ 9652.0 9125.0
RBX1 1418.0 4877.0
RCC2 -6741.0 -781.0
RCE1 -3787.0 -2010.0
RCOR1 9795.0 9655.0
RCVRN -820.0 5399.0
RDH10 -7462.0 242.0
RDH11 8205.0 6140.0
RDH13 -9122.0 -8119.0
RDH14 -6385.0 -8364.0
RDH16 -8167.0 -6628.0
RDH5 670.0 1182.0
REEP2 -6392.0 -2253.0
REEP3 9207.0 6263.0
REEP4 7784.0 9356.0
REEP5 8670.0 7858.0
REEP6 -9198.0 -8793.0
RELA -7305.0 2739.0
REST 534.0 1614.0
RET -10107.0 -2874.0
RETSAT -342.0 2405.0
RFNG 7041.0 8287.0
RGL1 7936.0 8025.0
RGL2 4873.0 9252.0
RGL3 8964.0 5107.0
RGR -1629.0 4770.0
RGS1 -2046.0 -7721.0
RGS10 7095.0 4207.0
RGS12 -10040.0 -9146.0
RGS14 6170.0 7437.0
RGS16 9903.0 1829.0
RGS17 2809.0 3533.0
RGS18 8905.0 6197.0
RGS19 5767.0 8525.0
RGS2 7298.0 8198.0
RGS3 -10555.0 5468.0
RGS5 -2997.0 -4806.0
RGS6 6835.0 6389.0
RGS9 -10609.0 -4448.0
RHEB 8786.0 7416.0
RHOA 8351.0 8888.0
RHOB -4807.0 3859.0
RHOBTB1 9208.0 7887.0
RHOBTB2 -8154.0 -1237.0
RHOC -11158.0 -4627.0
RHOF -11160.0 -10418.0
RHOG 7549.0 9255.0
RHOH -6870.0 -9730.0
RHOQ 9504.0 6692.0
RHOT1 10010.0 9811.0
RHOT2 -6252.0 -2090.0
RHOU 7924.0 9743.0
RHPN1 2265.0 -8079.0
RHPN2 -2702.0 -4003.0
RICTOR -3978.0 -9726.0
RING1 -6720.0 548.0
RIPK1 -10879.0 -4699.0
RIPK2 1665.0 2297.0
RIT1 9696.0 9723.0
RLN2 -3997.0 -8672.0
RLN3 -3200.0 7456.0
RNF111 6509.0 6215.0
RNF146 8442.0 9760.0
RNF2 5589.0 3400.0
RNF31 -9748.0 -5634.0
RNF41 8699.0 9075.0
RNF43 -9524.0 -11210.0
ROCK1 8315.0 7930.0
ROCK2 7628.0 6719.0
ROR1 2411.0 -2323.0
RPGRIP1L -3201.0 -10534.0
RPS27 -9041.0 -7909.0
RPS27A -3555.0 -7070.0
RPS6 -1613.0 -5951.0
RPS6KA1 -105.0 9153.0
RPS6KA2 -5428.0 3882.0
RPS6KA3 2859.0 3437.0
RPS6KA5 -3980.0 -11177.0
RPS6KB1 6780.0 -7046.0
RPS6KB2 -4855.0 4416.0
RPTOR -10162.0 -5989.0
RRAGA -920.0 7747.0
RRAGB 5841.0 -2648.0
RRAGC 6727.0 4618.0
RRAGD 9588.0 8860.0
RRH 576.0 -7474.0
RTKN -11144.0 -10917.0
RTN4 9617.0 9853.0
RTP4 -9692.0 -9215.0
RTP5 -8694.0 -4394.0
RUNX1 7796.0 7867.0
RUNX3 -11261.0 -9989.0
RUVBL1 -5940.0 -5741.0
RXFP2 9389.0 5911.0
RXFP4 176.0 -3623.0
RXRA 6327.0 8932.0
RXRB -7622.0 2709.0
RYK -835.0 -9020.0
S100A8 10041.0 10093.0
S100A9 10110.0 10116.0
S100B -8212.0 -1271.0
S1PR1 -10750.0 -4787.0
S1PR2 -10260.0 -9397.0
S1PR3 9261.0 3085.0
S1PR4 -7834.0 6506.0
S1PR5 -11278.0 -8550.0
SAG 170.0 1178.0
SALL4 -8382.0 -2248.0
SAV1 2674.0 720.0
SCAI -420.0 -7606.0
SCD 6578.0 3616.0
SCMH1 2787.0 -7207.0
SCRIB -8867.0 2824.0
SCT -10916.0 -9122.0
SCUBE2 -3619.0 -4721.0
SDC2 7232.0 4710.0
SDC3 3723.0 2630.0
SDC4 6516.0 7115.0
SEC13 2125.0 6861.0
SEH1L 7189.0 -8511.0
SEL1L 7157.0 7252.0
SEM1 993.0 5942.0
SEPTIN7 -3959.0 1036.0
SERPINE1 7839.0 8101.0
SFN -918.0 1127.0
SFPQ 8031.0 -220.0
SGK1 8717.0 2303.0
SGO1 -7321.0 -4581.0
SGO2 285.0 -3804.0
SH2B1 -6398.0 -6874.0
SH2B2 4083.0 9454.0
SH2B3 3129.0 4903.0
SH2D2A -11211.0 -10672.0
SH3GL1 4634.0 8807.0
SH3KBP1 4345.0 7311.0
SHARPIN -1147.0 7585.0
SHB -4316.0 7281.0
SHC1 -3416.0 5815.0
SHC3 9229.0 -1001.0
SHOC2 8573.0 7262.0
SIRT6 2567.0 8277.0
SKA1 4635.0 1882.0
SKA2 -7953.0 -5579.0
SKI -9589.0 -8552.0
SKIL -3992.0 1308.0
SKP1 8120.0 2700.0
SLC24A1 -9823.0 -8533.0
SLC38A9 3444.0 4290.0
SMAD1 7656.0 9731.0
SMAD2 5238.0 5871.0
SMAD3 -10084.0 -10081.0
SMAD4 -3009.0 -6696.0
SMAD5 -1081.0 -3858.0
SMAD6 8386.0 8091.0
SMAD7 -11234.0 -5230.0
SMAD9 5071.0 -8439.0
SMARCA4 -2731.0 7803.0
SMC1A -2815.0 3295.0
SMC3 6086.0 -4018.0
SMPD2 -7187.0 6202.0
SMPD3 -11070.0 -10458.0
SMURF1 -9318.0 2452.0
SMURF2 -9128.0 -7045.0
SNAI1 8579.0 9257.0
SNW1 6824.0 5161.0
SNX3 9914.0 9837.0
SOCS1 -219.0 6051.0
SOCS3 9830.0 10110.0
SOCS6 8906.0 9207.0
SORCS3 -926.0 -7702.0
SOS1 3534.0 -7412.0
SOS2 9141.0 8628.0
SOX13 -10748.0 -8557.0
SOX4 5490.0 5191.0
SOX6 8955.0 3557.0
SOX7 2991.0 -6140.0
SP1 8282.0 9168.0
SPARC 9073.0 7195.0
SPC24 -1637.0 3696.0
SPDL1 -8869.0 -10380.0
SPHK1 8030.0 8271.0
SPINT1 9479.0 8293.0
SPINT2 8182.0 8874.0
SPOP 6033.0 367.0
SPOPL 9428.0 8504.0
SPPL2A 8242.0 7334.0
SPPL2B -3106.0 -3652.0
SPRED1 -7983.0 -6504.0
SPRED2 -404.0 8453.0
SPRED3 -6894.0 -4695.0
SPRY1 -6300.0 4904.0
SPRY2 -10148.0 1940.0
SPTA1 9470.0 6216.0
SPTAN1 -10174.0 -8889.0
SPTB 9958.0 9302.0
SPTBN1 -6572.0 -6164.0
SPTBN2 -5447.0 -3871.0
SPTBN5 -7557.0 -461.0
SQSTM1 4693.0 4549.0
SRC -6857.0 -7229.0
SREBF1 8758.0 5979.0
SRF 4035.0 7760.0
SRGAP1 6525.0 7219.0
SRGAP2 4493.0 7351.0
SRGAP3 -4761.0 -4198.0
SSTR2 4041.0 460.0
SSTR3 -7134.0 -9333.0
ST3GAL3 2775.0 828.0
ST3GAL4 -9921.0 7993.0
ST3GAL6 9317.0 5155.0
STAG1 -6902.0 -2525.0
STAG2 7287.0 5015.0
STAM 3046.0 2017.0
STAM2 8115.0 5912.0
STAP2 1543.0 -6936.0
STARD13 -2011.0 5301.0
STARD8 848.0 4743.0
STAT1 -7385.0 -11118.0
STAT3 8512.0 8606.0
STAT5A 6437.0 7973.0
STAT5B 4758.0 7433.0
STAT6 2936.0 7753.0
STK11 -70.0 4172.0
STK3 9764.0 9192.0
STK4 -3783.0 2631.0
STMN1 -6650.0 -7184.0
STRADA -2271.0 4569.0
STRADB 9990.0 7814.0
STRAP 7901.0 6716.0
STRN 215.0 5171.0
STUB1 -7516.0 3468.0
SUCNR1 9422.0 4078.0
SUFU 7750.0 9766.0
SUZ12 4539.0 -3535.0
SYDE2 7572.0 -7169.0
SYK 9464.0 9848.0
SYNGAP1 -6138.0 -8178.0
SYVN1 734.0 2029.0
TAB1 6623.0 5746.0
TAB2 9197.0 5726.0
TAB3 3912.0 3647.0
TACC3 10034.0 9583.0
TACR2 -3169.0 3656.0
TAGAP -10622.0 -11214.0
TAOK1 5604.0 6063.0
TAS1R3 2681.0 -2430.0
TAS2R14 5608.0 -1571.0
TAS2R20 441.0 -5135.0
TAS2R3 825.0 -5793.0
TAS2R30 192.0 -4431.0
TAS2R4 -907.0 -7649.0
TAS2R5 2711.0 -8268.0
TAX1BP1 7469.0 5996.0
TAX1BP3 8203.0 8751.0
TBL1X 8359.0 8499.0
TBL1XR1 4714.0 4779.0
TBP -1224.0 -8870.0
TBXA2R 6830.0 4756.0
TCF12 -1570.0 891.0
TCF4 -6491.0 -2021.0
TCF7 -2790.0 -11149.0
TCF7L1 -1964.0 2145.0
TCF7L2 -10402.0 -1302.0
TCIRG1 1085.0 9058.0
TEC 8165.0 7953.0
TERT 8288.0 -4814.0
TF 1794.0 1244.0
TFDP1 9824.0 8225.0
TFDP2 -11249.0 -10144.0
TGFA 7935.0 9686.0
TGFB1 -2566.0 6745.0
TGFBR1 -7960.0 3224.0
TGFBR2 -5037.0 6173.0
TGIF1 -8193.0 -5874.0
TGIF2 -2787.0 -8961.0
THBS1 1778.0 8102.0
THBS3 8361.0 6974.0
THBS4 -5938.0 -7645.0
THEM4 -5349.0 -11202.0
TIA1 4573.0 -6920.0
TIAL1 5514.0 -4583.0
TIAM1 5732.0 -809.0
TIAM2 -10122.0 -8001.0
TJP1 -1182.0 -6918.0
TJP2 4701.0 4505.0
TLE1 -10867.0 400.0
TLE2 3990.0 -9885.0
TLE3 6965.0 9696.0
TLE4 2341.0 8265.0
TLE5 -10837.0 -9839.0
TLN1 7865.0 9661.0
TLR9 -10413.0 -138.0
TMED2 6426.0 6360.0
TMED5 8987.0 6292.0
TNF -3598.0 -6316.0
TNFAIP3 -10682.0 -6292.0
TNFRSF10A 6128.0 171.0
TNFRSF10B 9578.0 8036.0
TNFRSF10D 10021.0 8559.0
TNFRSF1A 9563.0 9913.0
TNFSF10 8687.0 -264.0
TNKS -7769.0 -6024.0
TNKS2 604.0 1179.0
TNRC6A -831.0 -4972.0
TNRC6B -4840.0 -2293.0
TNRC6C -10738.0 -9183.0
TNS3 9978.0 9419.0
TNS4 -6130.0 2655.0
TP53 -7284.0 -8934.0
TPH1 -2180.0 -9746.0
TRADD 4485.0 -2275.0
TRAF1 -9861.0 -11077.0
TRAF2 -9898.0 -9879.0
TRAF6 -1767.0 2089.0
TRAT1 5825.0 -10715.0
TRIB1 7599.0 8026.0
TRIB3 -7572.0 -1651.0
TRIM27 9047.0 8593.0
TRIM33 -7370.0 -6772.0
TRIO -2029.0 3636.0
TRIP10 6573.0 1072.0
TRPC3 -9747.0 -5879.0
TRPC6 -4419.0 130.0
TRRAP -7730.0 -2671.0
TSC1 1502.0 -1612.0
TSC2 -4535.0 2859.0
TSHR 5881.0 -42.0
TTC21B -7826.0 -9922.0
TULP3 -10055.0 -10214.0
TYK2 4430.0 8605.0
UBA52 -1875.0 3023.0
UBB 8251.0 6157.0
UBC -1915.0 5825.0
UBE2D1 9825.0 9491.0
UBE2D3 9443.0 8783.0
UBE2M 2776.0 9251.0
UCHL5 -1550.0 -6617.0
UCN -3909.0 -2780.0
UHMK1 -2704.0 -1741.0
USF1 2491.0 6308.0
USF2 -25.0 8256.0
USP13 -4013.0 -5427.0
USP15 8878.0 4964.0
USP21 -4240.0 -4963.0
USP34 -268.0 385.0
USP4 7420.0 8819.0
USP7 5480.0 7173.0
USP8 8542.0 6497.0
USP9X 4318.0 6232.0
UTS2 -6607.0 -1059.0
UTS2B -8806.0 -1322.0
VAPA 9732.0 9322.0
VAV1 5553.0 8731.0
VAV2 -5033.0 -1339.0
VAV3 -6160.0 7203.0
VCL 7488.0 7955.0
VCP 3600.0 7754.0
VEGFA 8464.0 8215.0
VEGFB -7685.0 -5963.0
VIPR1 -2635.0 -5038.0
VIPR2 -11038.0 -10105.0
VPS26A 7873.0 6528.0
VPS29 5940.0 2690.0
VPS35 8235.0 6328.0
VRK3 -7245.0 5798.0
VWF 6949.0 7780.0
WAS 8258.0 9323.0
WASF1 10091.0 10132.0
WASF2 7535.0 9576.0
WASF3 8142.0 7240.0
WASL 899.0 1391.0
WDR19 1535.0 -7871.0
WDR35 -8752.0 -8605.0
WDR83 -3139.0 6345.0
WIPF1 -5700.0 3866.0
WIPF2 2722.0 7125.0
WLS 9595.0 7423.0
WNT1 -7238.0 -8407.0
WNT10A -6531.0 -8450.0
WNT10B -9917.0 -7977.0
WNT11 9481.0 9830.0
WNT16 -6468.0 -3003.0
WNT2B -3933.0 -2393.0
WNT3 -6507.0 -2617.0
WNT4 -5401.0 -2168.0
WNT5B -1354.0 1462.0
WNT6 6264.0 5014.0
WNT7A 1684.0 -10965.0
WNT8B -803.0 -2558.0
WNT9A -4952.0 -3203.0
WNT9B -3400.0 3438.0
WWC1 2740.0 953.0
WWOX -10530.0 -7862.0
WWP1 813.0 -10536.0
WWP2 6396.0 8805.0
WWTR1 -6909.0 -4483.0
XCL1 -10078.0 -6162.0
XCL2 -9995.0 -9937.0
XCR1 -10303.0 5149.0
XIAP 2120.0 1654.0
XK 10092.0 9984.0
XPO1 6563.0 -3235.0
YBX1 -3216.0 5187.0
YES1 -11138.0 -8566.0
YWHAB 8274.0 6101.0
YWHAE 9721.0 9563.0
YWHAG 9658.0 9994.0
YWHAH 9519.0 9189.0
YWHAQ -9021.0 -1643.0
YWHAZ 5165.0 5861.0
YY1 -627.0 3060.0
ZDHHC21 2487.0 -7571.0
ZDHHC7 9610.0 8503.0
ZDHHC9 9626.0 9089.0
ZFYVE16 8981.0 7642.0
ZFYVE9 -4592.0 -7944.0
ZNF217 3452.0 4654.0
ZNRF3 3239.0 -4029.0
ZRANB1 4893.0 3821.0
ZW10 5778.0 -752.0
ZWILCH -9080.0 -10492.0
ZWINT -1751.0 -5219.0



Vesicle-mediated transport

Vesicle-mediated transport
metric value
setSize 644
pMANOVA 3.04e-33
p.adjustMANOVA 6.9e-31
s.dist 0.347
s.low.CRP 0.207
s.high.CRP 0.279
p.low.CRP 3.64e-19
p.high.CRP 1.28e-33




Top 20 genes
Gene low CRP high CRP
STAB1 10077 10111
F5 10084 10070
RAB13 10014 10088
VAMP7 10053 10044
CD163 10038 10038
RAB32 10006 10036
PLIN3 9856 10099
HP 9925 10000
CD36 10064 9814
RAB31 9956 9895
GNS 9627 10060
YWHAG 9658 9994
PLA2G4A 9622 10024
GRB2 9631 9985
ITSN1 9969 9600
AGFG1 10023 9542
TBC1D2 9498 9999
SBF2 9757 9727
APP 9951 9504
SERPINA1 9571 9817

Click HERE to show all gene set members

All member genes
low CRP high CRP
AAK1 -9118 -5763
ACBD3 7444 5845
ACTR10 8589 7569
ACTR1A -2833 8680
ACTR2 8743 7962
ACTR3 8622 7832
ADRB2 -11122 -7027
AGFG1 10023 9542
AGPAT3 6352 4771
AKT1 -4794 6231
AKT2 -8391 5504
AKT3 -9616 -10833
ALB 1254 3551
ALS2 3063 3862
ALS2CL -75 -10424
AMPH 6181 9351
ANK1 9797 8626
ANK3 3262 -7407
ANKRD27 -8124 4217
ANKRD28 -5795 -3898
AP1B1 8214 9804
AP1G1 -1796 5288
AP1G2 -3962 -4194
AP1M1 -3219 8558
AP1M2 4764 1487
AP1S1 9235 9982
AP1S2 6862 -6065
AP1S3 -5309 -4187
AP2A1 -3194 9104
AP2A2 3196 9217
AP2B1 -9145 2444
AP2M1 7742 9334
AP2S1 7422 8877
AP3B1 8649 9145
AP3S1 8709 7921
AP4B1 -7534 -3574
AP4E1 8480 5988
AP4M1 -6697 3666
AP4S1 3407 -6525
APOE -5022 1771
APOL1 -7427 -4732
APP 9951 9504
ARCN1 4082 6402
AREG 4465 7165
ARF1 8465 9910
ARF3 5651 9049
ARF4 9859 9444
ARF5 5736 9180
ARF6 -2986 3785
ARFGAP1 -6136 2991
ARFGAP2 -8987 2096
ARFGAP3 -6040 5157
ARFIP2 -2956 -529
ARFRP1 -8821 -1241
ARL1 433 -3992
ARPC1A 8875 9605
ARPC2 5327 8212
ARPC3 8430 8946
ARPC4 4637 8915
ARPC5 9301 9174
ARRB1 -4581 4541
ARRB2 7827 9274
ASPSCR1 -3774 -3855
AVPR2 1919 -154
BET1 7030 -4395
BET1L -7832 -2582
BICD1 -8225 -5006
BICD2 8006 9959
BIN1 -9734 -10132
BLOC1S1 5994 9870
BLOC1S3 -9500 -3067
BLOC1S4 -9130 -2048
BLOC1S6 8956 6373
BNIP1 -3293 -5463
C2CD5 455 -7716
CALM1 -6645 1321
CALR 6685 6374
CAPZA1 8666 8511
CAPZA2 9698 8474
CAPZB 6100 8926
CBL 6620 8302
CCZ1 1286 5422
CCZ1B -932 2308
CD163 10038 10038
CD36 10064 9814
CD3D -9569 -10471
CD3G -9054 -10504
CD4 3147 -5743
CD55 9326 9842
CD59 4075 5772
CENPE -3467 886
CHM 3845 3159
CHML 5118 -3431
CHMP2A 8348 9510
CHMP2B 7436 5296
CHMP3 8980 8782
CHMP4A -1130 4862
CHMP4B 8338 9679
CHMP5 5879 5138
CHMP6 -6653 8292
CHMP7 -4593 -8038
CLINT1 -2323 4581
CLTA 8416 8998
CLTB -2857 8274
CLTC 9376 9720
CLTCL1 10011 9218
CNIH1 9316 7116
CNIH2 701 601
CNIH3 -8173 -6989
COG1 -10399 -10838
COG2 -1210 -5915
COG3 3891 -5333
COG4 -4813 2002
COG5 1617 -3368
COG6 1512 -6280
COG7 2191 6149
COG8 -2814 2839
COL1A2 5690 684
COL4A2 1717 838
COL7A1 3993 7683
COLEC12 -5943 -2495
COPA 7617 9591
COPB1 8213 7283
COPB2 8531 8034
COPE 365 8719
COPG1 2542 9195
COPG2 7905 8313
COPS2 8864 5037
COPS3 7364 5716
COPS4 1748 2715
COPS5 3882 5135
COPS6 -3920 4485
COPS7A 1707 8090
COPS7B -9179 -6481
COPS8 -1206 -8494
COPZ1 2549 5017
COPZ2 -9229 -9247
CPD 8389 9739
CSNK1D -10030 6117
CTSC -7528 5285
CTSZ 8972 9860
CTTN 7016 6516
CUX1 8954 9964
CYTH1 -11020 -10918
CYTH2 -5796 4527
CYTH3 -10332 -415
CYTH4 -3373 7558
DAB2 3735 9712
DCTN1 -5984 7873
DCTN2 8504 10012
DCTN3 325 7904
DCTN4 7967 9572
DCTN5 -7505 664
DCTN6 7871 7759
DENND1A 7886 8109
DENND1B -8424 -6268
DENND1C -8451 -2822
DENND2A -6339 -7276
DENND2C 3782 6386
DENND2D -11035 -10741
DENND3 7518 8410
DENND4A 78 -5656
DENND4B -3397 6083
DENND4C -3825 -6581
DENND5A 8536 7893
DENND5B 461 -5154
DENND6A -1706 1438
DENND6B 4313 3006
DNAJC6 6237 4061
DNASE2 6443 7266
DNM1 6883 3239
DNM2 -6816 8202
DNM3 7927 7198
DTNBP1 -4743 4629
DVL2 -10305 -7147
DYNC1H1 -8881 -2533
DYNC1I1 7141 2722
DYNC1I2 8160 8196
DYNC1LI1 7894 6997
DYNC1LI2 3494 5636
DYNLL1 6026 6499
DYNLL2 -6325 -225
EGF 9244 8355
EPN1 5120 9372
EPN2 -6096 -1735
EPS15 6185 4175
EPS15L1 -8354 6665
EREG -837 3226
EXOC1 7856 5981
EXOC2 -4967 -5340
EXOC3 -1111 6579
EXOC4 3396 7066
EXOC5 7495 3245
EXOC6 9570 9004
EXOC7 -5279 7572
EXOC8 -3430 2362
F5 10084 10070
F8 7498 7167
FCHO1 -3203 -76
FCHO2 8546 8432
FNBP1 -6673 3651
FNBP1L 9365 8493
FTH1 3543 5337
FTL 8704 9324
FZD4 -10858 -7985
GABARAP 8114 8339
GABARAPL2 9716 9166
GAK -5204 6408
GALNT1 7249 6590
GALNT2 8571 9697
GAPVD1 7396 7396
GBF1 -8933 1807
GCC1 -1592 4456
GCC2 2224 -8694
GDI1 2059 7275
GDI2 8206 7892
GGA1 -964 3744
GGA2 -8234 -3297
GGA3 509 5673
GJB6 -2646 5614
GJC1 -382 1106
GJC2 1419 2222
GJD3 8186 8611
GNS 9627 10060
GOLGA1 -8499 4971
GOLGA2 -878 8019
GOLGA4 -783 -4010
GOLGA5 6321 5485
GOLGB1 -242 -5768
GOLIM4 1630 7798
GORASP1 7651 6560
GOSR1 -4021 2971
GOSR2 -2437 1468
GPS1 -8718 1571
GRB2 9631 9985
GRK2 757 7818
GRK3 8742 6150
HBA1 10009 8734
HBB 10013 8750
HBEGF 5089 5189
HGS -381 6840
HIP1 5859 9044
HIP1R -8953 -9087
HP 9925 10000
HPS1 1337 7264
HPS4 -9603 -9743
HPX 477 -1968
HSP90AA1 5309 410
HSP90B1 7042 372
HSPA8 -8286 -8908
HSPH1 -1504 -8662
HYOU1 -6582 2512
IGF2R -1133 9240
IGHA1 4926 -5918
IGHA2 2335 -2345
IGHV1-2 5956 -3146
IGHV1-46 3766 -2976
IGHV1-69 2354 -2328
IGHV2-5 4451 -1972
IGHV2-70 -3315 -2159
IGHV3-11 3518 -4591
IGHV3-13 799 -2451
IGHV3-23 6032 -5092
IGHV3-30 2500 -5193
IGHV3-33 98 -4138
IGHV3-48 3183 -4340
IGHV3-53 3131 -1786
IGHV3-7 4185 -3630
IGHV4-34 1144 -4007
IGHV4-39 3786 -6542
IGHV4-59 4532 -5870
IGKC 2773 -6437
IGKV1-12 725 -6674
IGKV1-16 6217 -5451
IGKV1-17 -241 -2794
IGKV1-33 5955 -6384
IGKV1-5 6127 -5162
IGKV1D-39 5018 -2677
IGKV2-28 1440 -6662
IGKV2-30 5205 -5349
IGKV2D-28 -7224 -2947
IGKV3-11 5548 -7167
IGKV3-15 3174 -4687
IGKV3-20 3704 -5021
IGKV3D-20 -1830 -4618
IGKV4-1 2812 -4988
IGKV5-2 5226 -2682
IGLC1 -2813 -6176
IGLC2 -258 -6539
IGLC3 -2958 -4378
IGLC7 -3403 -4490
IGLV1-36 3522 -5030
IGLV1-40 163 -5497
IGLV1-44 4742 -5791
IGLV1-47 231 -6633
IGLV1-51 1708 -6601
IGLV10-54 -5422 316
IGLV2-11 870 -3205
IGLV2-14 -5127 -8197
IGLV2-18 2015 -2963
IGLV2-23 2029 -4201
IGLV2-8 4818 -5256
IGLV3-1 -96 -5140
IGLV3-12 -7299 -6816
IGLV3-19 4006 -5611
IGLV3-21 -975 -6062
IGLV3-25 -942 -5485
IGLV3-27 -5365 -4834
IGLV4-69 1344 -2261
IGLV5-45 4194 -7364
IGLV6-57 1834 -5837
IGLV7-43 4854 -2823
IGLV7-46 2445 -3619
IGLV8-61 -3989 -5208
IL7R -4956 -11140
ITSN1 9969 9600
ITSN2 7119 5093
JCHAIN 4874 -8700
KDELR1 9552 9681
KDELR2 8771 7531
KDELR3 2255 -3318
KIAA0319 -1650 3716
KIF11 -140 1030
KIF13B 1563 7357
KIF15 -4399 -3471
KIF16B 4416 3004
KIF18A -5118 -1862
KIF18B -3932 1641
KIF19 -10944 -8869
KIF1B 8577 8548
KIF1C 6981 8811
KIF20A 5368 4706
KIF20B -962 -8226
KIF21A -10337 -10254
KIF21B -10698 -135
KIF22 -10995 -11246
KIF23 8000 4957
KIF26A -155 -6527
KIF26B -10618 -9336
KIF27 5469 1812
KIF28P -7127 -4560
KIF2A 2515 -1329
KIF2C 2032 104
KIF3A -9378 -11000
KIF3B 3757 4323
KIF3C 7590 9010
KIF4A -1703 4331
KIF5A -7037 -7903
KIF5B 9540 8103
KIF5C -2924 -10718
KIF6 2741 806
KIF9 -1185 6392
KIFAP3 -8849 -4476
KIFC1 -3213 1241
KIFC2 -900 -938
KLC1 1745 7386
KLC2 -6674 -7322
KLC3 8390 7398
KLC4 -9223 -3527
LDLR 2463 6531
LDLRAP1 -668 -10304
LMAN1 -1255 -10522
LMAN2 2397 8522
LMAN2L 7675 6680
LNPEP -8634 -6784
LRP1 9226 9878
LRP2 964 1845
M6PR -7566 -3638
MADD -10731 -7647
MAN1A1 4965 9297
MAN1A2 -1459 -993
MAN1C1 1436 -8761
MAN2A1 5542 -2948
MAN2A2 1864 8354
MAP1LC3B 7597 8663
MARCO 6219 9851
MCFD2 7963 7485
MIA2 6640 5566
MIA3 3397 -6425
MON1A -8311 2318
MON1B 111 8054
MSR1 -528 1494
MVB12A 6023 8501
MVB12B 2755 6228
MYH9 1879 8348
MYO1C 6395 2929
MYO5A 6789 7727
MYO6 -10507 -8938
NAA30 -5891 -7939
NAA35 -9061 -9861
NAA38 3081 9471
NAPA -2447 3305
NAPB -291 -2004
NAPG 7409 3591
NBAS 1380 1565
NECAP1 5273 2539
NECAP2 2916 4382
NEDD8 -156 8587
NSF 8895 9680
OCRL 7540 6631
OPTN -10447 -9518
PACSIN1 -11257 -11175
PACSIN2 8024 8785
PAFAH1B1 -336 6894
PAFAH1B2 7693 7761
PAFAH1B3 5824 4526
PICALM 9406 9673
PIK3C2A 1258 -5821
PIP5K1C -4447 6435
PLA2G4A 9622 10024
PLA2G6 -10753 -10993
PLIN3 9856 10099
POLG -10578 -1697
PPP6C 8559 6316
PPP6R1 -5320 7658
PPP6R3 3008 3925
PREB -1638 8142
PRKAB1 253 2895
PRKAB2 -3794 -7488
PRKAG1 1272 7037
PRKAG2 7892 7
PUM1 205 5294
RAB10 9303 9477
RAB11A 9786 8252
RAB11B -3172 6936
RAB12 5316 -2681
RAB13 10014 10088
RAB14 8215 7014
RAB18 9425 7287
RAB1A 9700 9407
RAB1B 5676 9455
RAB21 7222 6309
RAB27A 9164 8675
RAB27B -847 4689
RAB30 -7367 -8558
RAB31 9956 9895
RAB32 10006 10036
RAB33A -10854 -5029
RAB33B 8756 6897
RAB35 -6982 6352
RAB36 651 6588
RAB38 -10061 -3007
RAB39A 8587 6613
RAB39B -9791 -9905
RAB3A 7816 8757
RAB3GAP1 8630 5252
RAB3GAP2 4746 4797
RAB3IP 6917 2082
RAB41 -20 -4213
RAB43 4478 7506
RAB4A 9473 7027
RAB5A 8478 6815
RAB5B 3295 7820
RAB5C 7846 9422
RAB6A 8487 8616
RAB6B 6925 6712
RAB7A 8897 9367
RAB7B -7654 2220
RAB8A 540 5295
RAB8B 6227 7055
RAB9A 2889 5200
RAB9B -5682 -4620
RABEP1 -9142 -9849
RABEPK -1567 7092
RABGAP1 4102 2968
RABGEF1 8434 7639
RAC1 9052 9614
RACGAP1 3340 3770
RALA 7124 1151
RALGAPA2 9257 9433
RALGAPB -4707 -1027
REPS1 -7182 -2813
REPS2 7607 8723
RGP1 -2026 6446
RHOBTB3 -11228 -2363
RHOQ 9504 6692
RIC1 7981 6900
RIN1 5337 8446
RIN2 9710 8688
RINL -10942 -2982
RINT1 1211 -10524
RPS27A -3555 -7070
SAR1B 8795 5984
SBF1 -10462 -5210
SBF2 9757 9727
SCARB1 7210 6035
SCARB2 7273 5044
SCARF1 6500 -1228
SCFD1 4551 3924
SCGB3A2 718 -1063
SCOC 7819 -5600
SEC13 2125 6861
SEC16A -2929 6748
SEC16B -1454 1213
SEC22A 374 -4424
SEC22B 8663 4943
SEC22C -2377 -1611
SEC23A 8776 6905
SEC23IP 5231 -574
SEC24A 8318 7788
SEC24B 1663 5398
SEC24C -9662 3561
SEC24D 8017 8795
SEC31A 1743 2474
SERPINA1 9571 9817
SFN -918 1127
SH3D19 1556 -4586
SH3GL1 4634 8807
SH3KBP1 4345 7311
SLC2A8 -10538 -9148
SNAP23 9586 8642
SNAP29 -1741 8902
SNAPIN 6576 8237
SNF8 2113 7859
SNX18 -1909 8980
SNX2 9104 7671
SNX5 -3170 -276
SNX9 -1545 1119
SORT1 10022 9241
SPARC 9073 7195
SPTA1 9470 6216
SPTAN1 -10174 -8889
SPTB 9958 9302
SPTBN1 -6572 -6164
SPTBN2 -5447 -3871
SPTBN5 -7557 -461
SRC -6857 -7229
SSC5D -3756 -4645
STAB1 10077 10111
STAB2 7035 5388
STAM 3046 2017
STAM2 8115 5912
STON1 3492 2681
STON2 2975 4565
STX10 9426 9350
STX16 5855 4189
STX17 -4480 -10772
STX18 566 6529
STX4 -7285 5736
STX5 3566 8258
STX6 7335 9578
STXBP3 9347 6785
SURF4 3781 8016
SYNJ1 5518 6949
SYNJ2 -6592 -7005
SYS1 -2469 2886
SYT1 6818 4381
SYT11 -10523 504
SYT2 -9931 3980
SYTL1 -9643 -7469
TBC1D1 4645 8191
TBC1D10A -11008 -7682
TBC1D10B 5776 9261
TBC1D10C -10716 -9378
TBC1D13 -8268 6866
TBC1D14 9253 9633
TBC1D15 8643 1524
TBC1D16 -2932 6664
TBC1D17 -8174 -5848
TBC1D2 9498 9999
TBC1D20 -6556 3818
TBC1D24 3703 4341
TBC1D25 -10571 1633
TBC1D3 498 -353
TBC1D4 -2031 -11212
TBC1D7 5088 7715
TBC1D8B 1187 1823
TF 1794 1244
TFG 8930 6725
TFRC 2181 1526
TGFA 7935 9686
TGOLN2 8606 9683
TJP1 -1182 -6918
TMED10 35 2168
TMED2 6426 6360
TMED3 -2098 4751
TMED7 9038 7918
TMED9 917 9007
TMEM115 31 6881
TMF1 5973 2223
TOR1A 7721 8423
TOR1B -8940 1768
TPD52 -6451 -8296
TPD52L1 -5873 -1009
TRAPPC1 5277 9110
TRAPPC10 -10478 -2812
TRAPPC11 8029 4815
TRAPPC12 4595 7519
TRAPPC13 4365 -4316
TRAPPC2 -8890 -5344
TRAPPC2L -350 -932
TRAPPC3 6827 7922
TRAPPC4 -7161 -2663
TRAPPC5 4081 6280
TRAPPC6A -7665 -10218
TRAPPC6B 6230 4019
TRAPPC8 7266 7046
TRAPPC9 921 7473
TRIP10 6573 1072
TRIP11 5087 -2116
TSC1 1502 -1612
TSC2 -4535 2859
TSG101 8461 7757
TXNDC5 6834 -3539
UBA52 -1875 3023
UBAP1 9074 9269
UBB 8251 6157
UBC -1915 5825
UBQLN1 5050 5353
UBQLN2 7704 5498
ULK1 1924 8728
USE1 1304 2460
USO1 6916 3905
USP6NL 8168 3185
VAMP2 -9677 -10779
VAMP3 9204 8284
VAMP4 7662 1445
VAMP7 10053 10044
VAMP8 2890 6767
VPS25 4731 8821
VPS28 388 6727
VPS36 2419 -7295
VPS37A 7815 6346
VPS37B -9566 6955
VPS37C 8342 8556
VPS45 6527 1884
VPS4A -5744 4778
VPS4B 5540 5495
VPS51 -8466 -1916
VPS52 -4410 -725
VPS53 -4323 2773
VPS54 9119 6993
VTA1 7807 5732
VTI1A -2998 7207
WASL 899 1391
YIPF6 7611 5809
YKT6 -3724 6818
YWHAB 8274 6101
YWHAE 9721 9563
YWHAG 9658 9994
YWHAH 9519 9189
YWHAQ -9021 -1643
YWHAZ 5165 5861
ZW10 5778 -752



Metabolism

Metabolism
metric value
setSize 1758
pMANOVA 1.9e-30
p.adjustMANOVA 3.71e-28
s.dist 0.197
s.low.CRP 0.103
s.high.CRP 0.168
p.low.CRP 5.85e-13
p.high.CRP 1.29e-31




Top 20 genes
Gene low CRP high CRP
PLBD1 10121 10138
PPARG 10111 10137
IDH1 10122 10092
CTSA 10083 10131
VCAN 10068 10125
IMPA2 10054 10113
PGD 10065 10089
PLB1 9997 10127
MGST1 10098 9993
DSE 9981 10103
BST1 10108 9972
TALDO1 10039 9995
CYP1B1 9899 10133
FAH 9973 10055
NMNAT2 9877 10130
PYGL 10071 9926
HADHB 10016 9979
GNA15 9871 10112
SLC25A37 10069 9899
PGAM1 9980 9987

Click HERE to show all gene set members

All member genes
low CRP high CRP
AAAS -8564 -4273
AACS -33 2141
AANAT -3281 1887
AASDHPPT 5030 -1866
AASS -5465 -9001
ABCA1 5566 7323
ABCB1 -11223 -9699
ABCB4 -1968 -4715
ABCB7 6690 -2967
ABCC1 686 2817
ABCC2 -1995 -911
ABCC3 5573 6872
ABCC5 1929 3348
ABCD1 6353 8582
ABCD4 -7007 -5916
ABCG2 -3030 1489
ABHD10 -1104 -5660
ABHD14B -8414 -7333
ABHD3 8545 6951
ABHD4 1373 8133
ABHD5 8602 8289
ABO 5974 1562
ACAA1 6662 9280
ACAA2 -1985 5348
ACACA 2977 6128
ACACB -6144 -9025
ACAD10 6343 5354
ACAD11 -5270 -10034
ACAD8 -6164 -796
ACAD9 152 1175
ACADL -1862 401
ACADM 7350 -3486
ACADS -4002 6806
ACADSB -4064 -10700
ACADVL 8805 8687
ACAT1 8245 4817
ACAT2 3136 -2924
ACBD4 -905 -3679
ACBD5 -7062 2964
ACBD6 -10077 -8638
ACBD7 5590 2323
ACER1 -1818 -8868
ACER2 5652 616
ACER3 9987 9382
ACLY -3163 7024
ACMSD 171 -3124
ACO2 -1456 5857
ACOT1 -7451 -1398
ACOT11 -4357 1862
ACOT13 6638 5659
ACOT2 -10662 -4993
ACOT4 -9703 -8244
ACOT7 -7000 678
ACOT8 6370 8924
ACOT9 4296 6690
ACOX1 9598 9253
ACOX2 8876 10071
ACOX3 1446 7517
ACOXL 6296 4342
ACP5 -1864 -702
ACP6 -4193 -2114
ACSBG1 -3996 1079
ACSF2 -10503 -8147
ACSF3 -2418 2062
ACSL1 9679 9692
ACSL3 8319 8132
ACSL4 9543 9115
ACSL5 -9738 -6853
ACSL6 5399 -8643
ACSM1 -7115 -8617
ACSM2A 1199 6808
ACSM2B 2766 -4024
ACSM3 -857 -6921
ACSM6 -700 5531
ACSS1 -10966 -9892
ACSS2 10095 9745
ACSS3 8598 9213
ACY1 -1118 -3475
ACY3 -5566 -8124
ADA -11159 -9413
ADAL -6780 -10573
ADCY2 -4785 -910
ADCY3 8645 9780
ADCY4 4042 6126
ADCY5 -8988 -4426
ADCY6 -4846 651
ADCY7 -8603 2306
ADCY9 -3025 2535
ADH1B 2909 -511
ADH5 -8052 -3672
ADHFE1 -3954 -3951
ADI1 7614 6399
ADIPOR1 10024 9730
ADIPOR2 -2709 7718
ADK 4255 -4736
ADO -869 69
ADPGK 6628 6763
ADPRM -2154 -9429
ADRA2A -416 4269
ADSL 8290 4286
AFMID 3024 7339
AGK -9841 -11206
AGL -3370 -1431
AGMAT 3795 -8093
AGPAT1 7745 9088
AGPAT2 9161 10022
AGPAT3 6352 4771
AGPAT4 -10357 -2707
AGPAT5 -1021 -9192
AGPS 8149 4749
AGRN -9794 -10649
AHCY -3099 3265
AHCYL1 6114 7566
AHR 9187 6903
AHRR -7879 -1783
AIMP1 6869 -8285
AIMP2 445 524
AIP -8999 2061
AK1 -6604 -8234
AK2 7579 1607
AK4 9604 9701
AK5 -8614 -10507
AK6 973 -3045
AK9 -687 1416
AKAP5 -11075 -11060
AKR1A1 -613 3270
AKR1B1 -10733 -10509
AKR1B15 7018 1575
AKR1C1 6158 -2806
AKR1C2 1132 -7880
AKR1C3 -11152 -8047
AKR7A2 -4590 4580
AKR7L 5066 -3528
AKT1 -4794 6231
ALAD 8384 9011
ALAS1 8849 7669
ALAS2 10119 8809
ALB 1254 3551
ALDH18A1 -10069 -8253
ALDH1A1 -8855 -11230
ALDH1B1 -9371 -8062
ALDH1L2 4444 5745
ALDH2 8896 8283
ALDH3A2 6046 457
ALDH3B1 8834 9423
ALDH4A1 9532 9906
ALDH6A1 3677 5816
ALDH7A1 1013 1729
ALDH9A1 2404 3617
ALDOA 9625 9857
ALDOB -5354 82
ALDOC -3 -2424
ALOX12 8526 7700
ALOX12B -5522 -6022
ALOX15 -6345 -9981
ALOX15B 9448 7656
ALOX5 9516 9496
ALOX5AP 4064 8312
AMACR -10395 -976
AMD1 7813 2044
AMDHD1 -2115 -1497
AMN 2539 -5736
AMPD2 3286 6238
AMPD3 9213 9215
AMT -5040 -5324
ANGPTL4 -7923 824
AOC1 6446 7328
AOC2 7544 6118
AOC3 1818 4459
APIP 6874 4793
APOA2 2715 7325
APOE -5022 1771
APOM -106 1435
APRT -2805 -663
ARF1 8465 9910
ARF3 5651 9049
ARG1 9021 8594
ARG2 5619 6557
ARNT 7974 9384
ARNTL -10595 821
ARSA -218 5556
ARSB 8124 8067
ARSD 8118 8210
ARSG -5202 -1774
ARSJ -1176 -6399
ARSK -8263 -10357
ARV1 -1109 -1377
AS3MT -2216 -7695
ASAH1 9274 8880
ASAH2 -7550 -7763
ASL -3833 8534
ASNS -2039 -9431
ASPA 4246 -1136
ASRGL1 5854 5273
ATIC -4273 -10792
ATP5F1A 7733 6192
ATP5F1B 6073 6672
ATP5F1C 8324 6069
ATP5F1D -1280 4939
ATP5F1E 4521 7444
ATP5MC1 -2478 -7018
ATP5MC2 -1240 4528
ATP5MC3 4018 6907
ATP5ME -5675 6020
ATP5MF 3962 7981
ATP5MG 2821 7078
ATP5PB 7378 7967
ATP5PD 8539 7454
ATP5PF 5530 7183
ATP5PO 6041 4761
AUH -6628 3142
AZIN1 7913 6989
AZIN2 -7731 -11012
B3GALNT1 1825 6391
B3GALT1 476 -5571
B3GALT2 -834 -6197
B3GALT4 -8624 8374
B3GALT6 -6286 -359
B3GAT1 -10805 -5919
B3GAT2 6544 -7311
B3GAT3 -7211 2864
B3GNT2 5152 5953
B3GNT4 -8399 -9205
B3GNT7 -11219 -9428
B4GALNT2 -601 2343
B4GALT1 -4177 7099
B4GALT2 -7253 -2349
B4GALT3 -9162 -7981
B4GALT4 -9971 3971
B4GALT5 8862 9469
B4GALT6 -10936 -1047
B4GALT7 -4388 -6269
B4GAT1 -4385 -4229
BCAT1 7240 8921
BCAT2 -3842 -127
BCKDHA 1687 7800
BCKDHB -2298 -11092
BCKDK 9069 9725
BCO2 -9464 -5280
BDH1 -4059 -10697
BDH2 -8089 -10646
BLVRA 8890 4419
BLVRB 10008 9667
BMX 6882 9193
BPGM 9916 8430
BPHL -6831 -6622
BPNT1 -788 765
BRIP1 -8997 -10362
BSG 9373 9841
BST1 10108 9972
BTD -10400 -10724
CA1 10107 9363
CA13 7069 -1227
CA14 -7358 -2385
CA2 3967 3723
CA4 6753 9451
CA5B -8031 -9187
CA6 6303 -7159
CACNA1A -1070 -2879
CACNA1C -10151 -8799
CACNA1D 7066 2211
CACNA1E 7550 9054
CACNA2D2 -11060 -8835
CACNB2 -931 -6046
CACNB3 -359 1459
CAD -3235 -8762
CALM1 -6645 1321
CARM1 9361 9442
CARNMT1 -3897 -10008
CARNS1 -9588 -8496
CAV1 2492 1598
CBR1 1382 2892
CBR3 -1116 -10579
CBR4 961 -557
CBS -2287 7563
CCNC 7860 -2135
CD320 -9568 -7192
CD36 10064 9814
CD38 -10468 -10636
CD44 8303 9047
CDA 9766 9792
CDIPT 2094 7603
CDK19 6602 9278
CDK8 -3688 1375
CDS1 -529 -2994
CDS2 4323 8193
CEMIP -552 -9225
CEPT1 5983 -21
CERK -9345 843
CERS2 9130 9519
CERS3 2778 -4286
CERS4 -8028 -2091
CERS5 -7630 2065
CERS6 7455 5780
CERT1 9201 7883
CES1 10060 8572
CES2 2680 8786
CES3 -9501 -5359
CHAC2 792 -8116
CHD9 -4184 -2634
CHDH -4234 -717
CHKA 5698 6720
CHKB -3896 -1236
CHP1 9390 10098
CHPF -9547 -7418
CHPF2 6189 8421
CHPT1 9431 9184
CHST11 -909 7025
CHST12 -11243 -10751
CHST13 4790 8077
CHST14 -8319 4910
CHST15 9356 9443
CHST2 -11200 -1641
CHST5 -4196 631
CHST6 -784 -5074
CHST7 -9815 -4055
CHSY1 9045 8148
CIAO1 -8326 -4319
CIAO2B -3692 4729
CIAO3 -7563 600
CIAPIN1 -6999 -3757
CKB -11224 -7664
CKMT2 85 -6994
CLOCK -568 -7717
CMBL 8225 5599
CMPK1 6497 -3690
CNDP2 -4413 -2079
COASY 4792 9050
COMT 8187 8862
COQ10A -9781 -10192
COQ10B 5268 3825
COQ2 8170 7439
COQ3 -6671 -9086
COQ5 3745 7401
COQ6 -8755 -10621
COQ7 4553 5323
COQ9 -8539 -3566
COX10 -2044 -3674
COX11 -6868 -10699
COX14 -128 -367
COX15 7821 9027
COX16 6393 -2523
COX18 1784 -5108
COX19 -120 -5762
COX20 5486 -7788
COX4I1 3114 5078
COX5A 4760 7110
COX5B 2640 7972
COX6A1 -2950 7217
COX6B1 -115 7257
COX6C 968 1847
COX7A2L 8157 8161
COX7B -1007 6181
COX7C -1263 2447
COX8A 1001 8573
CPNE1 -7895 1521
CPNE3 7732 5446
CPNE7 -5324 -5968
CPOX 4509 -236
CPS1 -518 -2771
CPT1A 2381 6786
CPT1B -3067 -4000
CPT2 4442 8015
CPTP -2928 5586
CRAT 9280 9619
CREBBP -4951 6023
CRLS1 9938 8963
CROT -9474 -10996
CRYL1 2895 6387
CRYM 2246 8564
CS 4625 4523
CSAD 7055 8029
CSGALNACT1 3577 4219
CSGALNACT2 9419 8257
CSNK1G2 -8130 4845
CSNK2A1 3192 8248
CSNK2A2 6050 7886
CSNK2B 1222 5287
CSPG4 -5789 -2201
CTH -4832 -7719
CTPS1 -6274 -8536
CTPS2 4109 2550
CTRC -10799 -6135
CTSA 10083 10131
CUBN -446 -9567
CYB5A -274 -5346
CYB5B -10191 -6156
CYB5R3 8185 9788
CYC1 -4993 5801
CYCS 1400 -430
CYP1A2 -3599 1804
CYP1B1 9899 10133
CYP27A1 5365 3927
CYP2A6 -5336 -9006
CYP2C9 -1455 5957
CYP2D6 -5583 -8281
CYP2E1 -7402 -10555
CYP2R1 -9982 -6118
CYP2S1 -3167 -3060
CYP2U1 -10449 -10397
CYP3A43 2561 1049
CYP3A5 7531 -8926
CYP46A1 3429 -1761
CYP4F12 338 -4966
CYP4F22 -11214 -10272
CYP4F3 5306 6371
CYP4F8 -3981 186
CYP4V2 -7850 -8445
CYP51A1 7585 6990
CYP7B1 -4766 -2364
CYSLTR2 -2968 -8588
D2HGDH -4036 -4999
DARS1 7862 -2087
DBH -5056 -10427
DBI -1941 8632
DBT 2429 -6393
DCK -4075 -6767
DCTD -6860 -7246
DCTPP1 469 -404
DCXR -2729 2118
DDAH2 -1955 9328
DDHD1 -7729 -11016
DDHD2 -8127 -11095
DDO -1624 -3782
DECR1 6381 5874
DECR2 -34 2009
DEGS1 6718 6254
DEGS2 -10766 -7572
DERA 9044 8799
DGAT1 3473 6135
DGAT2 9319 9775
DGUOK -1299 4811
DHCR24 -6328 4423
DHCR7 1111 7390
DHFR 5872 5438
DHFR2 -4726 960
DHODH 42 -5669
DHRS7B 6356 8607
DHTKD1 3149 6628
DIO1 4371 -5489
DLAT -430 -1295
DLD 8131 7489
DLST -10329 300
DMAC2L -738 -7513
DNM2 -6816 8202
DNPH1 853 -2545
DPEP2 -4986 -926
DPEP3 -4594 -1297
DPYD 9749 9511
DSE 9981 10103
DSEL 4695 -5498
DTYMK -6669 -7826
DUOX1 -9681 -9527
DUT -1529 -4503
EBP -10781 -9206
ECHS1 1217 -1164
ECI1 -39 1998
ECI2 -9181 -10495
ECSIT 4110 5590
EEF1E1 -1005 -726
EEFSEC -9411 -5255
EHHADH 6611 6676
ELOVL1 2831 8404
ELOVL3 9817 8219
ELOVL4 -1358 -9048
ELOVL5 6808 6251
ELOVL6 -11059 -5972
ELOVL7 9219 7532
ENO1 9509 9247
ENO2 136 -9523
ENO3 -7820 -3755
ENOPH1 -8239 -6776
ENPP1 -9912 -5673
ENPP2 -222 2421
ENPP3 -3566 -10865
ENPP6 -972 727
ENTPD1 9534 8418
ENTPD4 -2121 -6681
ENTPD5 -991 -5130
ENTPD6 1608 -4742
ENTPD7 8308 8286
EP300 4311 7552
EPHX1 -5866 -9043
EPHX2 -1489 -11090
EPM2A -6163 -10075
EPRS1 4117 -3805
ERCC2 -795 5496
ESD 8928 5297
ESRRA 740 8079
ESYT1 -10789 -10656
ESYT2 -10180 -9316
ETFA 9418 8802
ETFB 6243 9120
ETFDH 9068 8381
ETHE1 8174 9459
ETNK1 5034 -2684
ETNK2 -9067 -6126
EXT1 5199 8182
EXT2 -6708 2518
FA2H 713 -4597
FAAH -2227 -5779
FAAH2 5259 -9362
FABP2 -2791 5054
FABP3 -8776 -7846
FABP5 4135 6969
FADS1 7716 8547
FADS2 -5372 3556
FAH 9973 10055
FAHD1 -1698 2361
FAM120B -1528 3105
FAR1 9850 8567
FAR2 10026 8691
FASN -3242 1451
FAU -5297 2810
FBP1 1389 9150
FDFT1 4112 8461
FDPS -1169 7584
FDX1 5786 1343
FDX2 -4897 -2162
FDXR 8050 3941
FECH 8800 5914
FH 1279 4122
FHL2 3293 4988
FIG4 9442 9960
FITM1 -6458 -3216
FITM2 2033 -6705
FLAD1 -9170 -2302
FLVCR1 -5808 -6526
FMO3 -1277 477
FOLR2 2768 -6707
FPGS -9870 -7370
FTCD 631 -8537
FUT1 8830 2443
FUT10 -3620 -4521
FUT11 -11147 -8561
FUT2 -6692 -8273
FUT4 8662 6704
FUT7 6880 9286
FXN -5780 -11067
G0S2 3165 1605
G6PC 5527 6482
G6PC3 -1222 5674
G6PD 8451 9963
GAA 8448 8356
GADL1 -18 342
GALC 7644 9719
GALE -3883 7600
GALK1 7917 9843
GALT -3830 -9697
GAMT -2239 -7568
GAPDH 9533 10074
GART -2276 -559
GATM -8442 -4076
GBA 8941 9735
GBA2 -5705 6458
GBE1 9173 8295
GCAT -1338 3752
GCDH -5792 2251
GCH1 -5676 -5013
GCHFR -3482 6857
GCK 1371 1141
GCLC -9821 -9262
GCLM -2840 6348
GCSH -5721 -6671
GDA 5411 209
GDE1 9232 8896
GDPD1 -7013 -524
GDPD3 6200 6580
GDPD5 -9141 -9606
GGCT 3687 -8176
GGPS1 5672 -3243
GGT1 8068 10073
GGT5 -6888 1713
GGT7 -4415 -8609
GK 9560 9415
GLA 8923 9083
GLB1 9091 9091
GLB1L 4424 2509
GLCE 9780 8377
GLDC 7316 -6266
GLIPR1 9841 6015
GLO1 647 -2916
GLRX 8489 8386
GLRX5 9772 7929
GLS -4689 -11229
GLS2 -2257 -7597
GLTP 6336 9890
GLUD1 6960 5370
GLUL 9002 9855
GLYAT 6250 3775
GLYCTK -9418 2911
GM2A 9396 9808
GMPR 9884 7932
GMPR2 1667 8907
GMPS -352 -3659
GNA11 5883 2815
GNA15 9871 10112
GNAI1 6562 2097
GNAI2 5861 9258
GNAQ 10007 8976
GNAS 8297 8173
GNB1 6908 9175
GNB2 6587 9064
GNB3 7806 -8406
GNB4 9340 6537
GNB5 6182 -475
GNG10 9939 9753
GNG11 8239 6403
GNG2 -10761 192
GNG3 4993 -794
GNG4 414 -2445
GNG5 8894 9403
GNG7 -2881 -4054
GNG8 4092 4604
GNGT2 -11227 -6988
GNMT 1558 2679
GNPAT 8372 6492
GNPDA1 9028 8774
GNPDA2 3391 -10448
GNS 9627 10060
GOT1 -9859 -8576
GOT2 -6850 -6878
GPAM -4790 -9067
GPAT2 -4992 -3853
GPAT3 8990 8251
GPAT4 -7656 7009
GPC1 -6229 -1709
GPC2 736 -5447
GPC4 -2862 -5115
GPCPD1 9553 8702
GPD1 -6288 -5099
GPD1L -7900 -8240
GPD2 8788 7751
GPHN -3866 -5388
GPI 3712 6865
GPS2 -6562 2341
GPT -7548 -8237
GPT2 3594 -1225
GPX1 9948 9589
GPX2 -4296 -1665
GPX4 3416 5814
GRHL1 -520 903
GRHPR -3353 3169
GSR 9580 9896
GSS -1339 2936
GSTA4 -9686 -5181
GSTK1 4449 -2605
GSTM1 -371 -72
GSTM2 -6597 -9649
GSTM3 3759 -4086
GSTM4 1189 1508
GSTM5 5977 3341
GSTO1 9193 9858
GSTO2 -7734 585
GSTP1 -3317 2661
GSTZ1 1734 6805
GUK1 2851 6227
GUSB 2374 9501
GYG1 9474 9547
GYS1 6988 7692
HAAO 9377 8099
HACD1 6205 4226
HACD2 3078 -2009
HACD3 -5333 -9766
HACD4 8287 6869
HACL1 -7200 -10652
HADH -8975 -10276
HADHA 8951 9801
HADHB 10016 9979
HAGH 4797 5573
HAL 8792 7565
HAS3 -7457 -2746
HDAC3 1719 6319
HDC 1112 -9441
HELZ2 -10464 -4663
HEXA 1650 2356
HEXB 9386 9202
HGD 1273 -131
HIBADH -4149 -6416
HIBCH 3603 -4123
HILPDA 4029 -2557
HK1 9170 9877
HK2 9564 10015
HK3 9953 9940
HLCS -10615 -8779
HMBS 8105 4914
HMGCL -183 7666
HMGCR 8736 8314
HMGCS1 -1269 -202
HMMR 1918 3372
HMOX1 6942 9285
HMOX2 -10770 -8356
HNMT 9535 7944
HPD 7429 7844
HPGD 5710 7919
HPRT1 7653 6119
HPSE 9514 8535
HS2ST1 4883 4379
HS3ST1 -5748 -2038
HS3ST2 707 2008
HS3ST3A1 -10675 -1285
HS3ST3B1 -10996 -2117
HS6ST1 -6509 7236
HSCB 2111 4371
HSD11B2 3975 4314
HSD17B1 6487 3122
HSD17B10 -1197 6037
HSD17B11 9269 7792
HSD17B12 8715 6838
HSD17B13 5139 5393
HSD17B2 207 4487
HSD17B4 9821 8748
HSD17B7 -2996 -10046
HSD17B8 -8758 -9338
HSD3B7 9875 10077
HSP90AA1 5309 410
HSP90AB1 2247 -6319
HSPG2 -7219 -5674
HTD2 4062 1001
HYAL1 888 4763
HYAL2 8387 9968
HYAL3 7507 4690
HYKK 5134 -7047
IARS1 -8945 -10625
IDH1 10122 10092
IDH2 -9305 2570
IDH3A -3606 -7589
IDH3B -2843 1337
IDH3G -1561 5206
IDI1 7412 7340
IDO1 -6837 -10712
IDO2 1622 -7350
IDS -7576 1999
IDUA -3629 -5066
IL4I1 -8058 -9173
IMPA1 2872 -1259
IMPA2 10054 10113
IMPDH1 9819 9891
IMPDH2 -3563 -10154
INMT 6458 -500
INPP1 -7915 3099
INPP4A -10541 -2748
INPP4B 2225 -11160
INPP5A 6792 7143
INPP5B -5371 -4931
INPP5D -10797 4515
INPP5E -2606 -9106
INPP5F -4077 -3372
INPP5K -7690 2475
INPPL1 9638 9488
INSIG1 -10932 -4568
INSIG2 7642 6198
IP6K1 -5639 6493
IP6K2 -10624 -3756
IPMK 9071 8040
IPPK -6068 5542
IQGAP1 7310 9366
ISCA1 8555 5358
ISCA2 3570 6901
ISCU -132 -319
ISYNA1 3321 -6308
ITPA -8858 -3293
ITPK1 1166 8412
ITPKB -10410 -8863
ITPKC 7219 9925
ITPR1 -5546 -5368
ITPR2 6833 6418
ITPR3 -8438 -9066
IVD -10945 -10288
IYD 6285 -3433
KARS1 1343 -4436
KCNB1 2984 2691
KCNG2 9574 10135
KCNJ11 -2546 -3545
KDSR 5554 -8807
KHK -6419 -4987
KMO -2360 -6755
KPNB1 -1223 3575
KYAT1 -571 -3381
KYAT3 6796 4355
KYNU 8053 7265
L2HGDH -3046 -9787
LARS1 8144 -9014
LBR 8953 8145
LCLAT1 2876 -770
LDHA 9587 8779
LDHAL6A -4503 -603
LDHB -1088 -10946
LDLR 2463 6531
LGMN -3548 -2820
LHPP 2376 219
LIAS 3306 -7154
LIPE -6752 -7655
LIPH -806 5104
LIPT1 -5367 -10939
LIPT2 -4191 -7084
LMBRD1 8148 6388
LPCAT1 -10952 2487
LPCAT2 9661 8661
LPCAT3 8263 9435
LPCAT4 -6623 -6856
LPGAT1 9154 8941
LPIN1 -9710 -9564
LPIN2 -2883 -5257
LPIN3 2760 -7145
LPL -2018 4002
LRP1 9226 9878
LRP10 -513 8129
LRP12 6551 7062
LRP2 964 1845
LRP8 -1100 5967
LRPPRC 570 -10454
LSS -10074 -7255
LTA4H 9933 9541
LTC4S -7039 2930
LYPLA1 9192 8174
LYRM4 -1017 -5927
LYVE1 8853 9498
MAN2B1 7665 7139
MAN2B2 -2053 5998
MAN2C1 -1511 -2870
MANBA 9330 6620
MAOA 9886 9426
MAOB 9713 8352
MAPKAPK2 -10572 6892
MARCKS -8068 309
MARS1 -5741 1098
MAT2A 3079 -4712
MAT2B -6654 -7646
MBOAT1 6932 5567
MBOAT2 9585 8220
MBOAT7 8301 9221
MBTPS1 1704 4208
MBTPS2 2221 584
MCAT 3071 6616
MCCC1 -4948 -7307
MCCC2 -7378 -10977
MCEE -318 -4292
MDH1 3388 2543
MDH2 -875 5729
ME1 9337 9516
ME2 9057 6477
ME3 -9562 -8105
MECR -5607 -5047
MED1 -2730 -1762
MED10 -5268 -7090
MED11 -5849 3435
MED12 -6426 4924
MED13 3230 3171
MED13L 5428 7259
MED14 -1391 1994
MED15 -9816 -5112
MED16 1626 7040
MED17 6659 2906
MED18 -3248 7029
MED19 4205 3722
MED20 4514 8084
MED21 2129 -7223
MED22 -1721 5575
MED23 -4613 -4897
MED24 -9186 -918
MED25 4853 7553
MED26 -5273 7174
MED27 -10124 -2305
MED28 2447 -1143
MED29 -9108 -967
MED30 -7460 -966
MED31 7152 -877
MED4 5576 3120
MED6 5195 -1751
MED7 1493 1153
MED8 7164 8014
MED9 -9724 -1868
MFSD2A 3282 -3810
MGLL 8873 7773
MGST1 10098 9993
MGST2 9282 9032
MGST3 8283 6230
MID1IP1 2483 4553
MIGA1 4402 -9507
MIGA2 -7400 -1345
MINPP1 -3813 1723
MIOX 1875 -2390
MLX 7548 9495
MLXIPL 6755 7894
MLYCD -8982 -5715
MMAA -7883 -9948
MMAB -6760 -7369
MMACHC -439 -6769
MMADHC 6035 6340
MMS19 -7671 -4309
MMUT 5151 3819
MOCOS 6125 2347
MOCS1 -10192 -831
MOCS2 100 -9585
MOCS3 -8576 -1711
MOGAT3 -5876 663
MORC2 -4157 -8774
MPC1 2651 -1040
MPC2 3432 5101
MPST 5978 9245
MRI1 -3204 -4509
MSMO1 3451 2480
MT-ATP6 -6161 1833
MT-ATP8 -8699 3719
MT-CO1 575 1906
MT-CO2 -1994 1965
MT-CO3 -1724 2140
MT-CYB -2748 -78
MT-ND1 -3881 -1394
MT-ND2 -6369 -3767
MT-ND3 -4723 -1060
MT-ND4 1457 1379
MT-ND5 -3288 283
MT-ND6 2811 366
MTAP 3191 -6757
MTF1 9635 9358
MTHFD1 -5578 -10905
MTHFD1L 5289 -960
MTHFD2 8787 8970
MTHFD2L 6927 2394
MTHFR 3128 6262
MTHFS 8224 9097
MTM1 9605 4142
MTMR1 -8862 357
MTMR10 8590 8475
MTMR12 -6255 2780
MTMR14 7743 8920
MTMR2 2 -1144
MTMR3 9216 9859
MTMR4 -1239 4307
MTMR6 8965 7813
MTMR7 -1669 -2653
MTMR8 -8236 -7927
MTMR9 4316 1779
MTR -9160 -11143
MTRR -620 3303
MVD -10176 2670
MVK -10455 -1828
N6AMT1 -6371 -10827
NAALAD2 6172 -8133
NADK 7764 8279
NADK2 -4292 -5028
NADSYN1 -4128 5826
NAGLU -9789 2532
NAGS -6221 6180
NAMPT 6071 8156
NAPRT 6522 8450
NAT1 8234 6530
NAT8L -11074 -8454
NAXD -7518 -3914
NAXE -4685 58
NCOA1 -1753 6268
NCOA2 -4443 3788
NCOA3 3630 4256
NCOA6 1381 7728
NCOR1 3309 7790
NCOR2 4843 9646
NDC1 -9151 -11223
NDOR1 1646 3966
NDST1 8496 9006
NDST2 7188 8498
NDUFA1 687 7917
NDUFA10 -5314 -4275
NDUFA11 -3202 3950
NDUFA12 -2153 565
NDUFA13 -3024 6982
NDUFA2 742 6906
NDUFA3 -6059 4507
NDUFA4 4653 7646
NDUFA5 4598 -5814
NDUFA6 4008 6572
NDUFA7 490 7471
NDUFA8 6307 4716
NDUFA9 -8914 -3000
NDUFAB1 7789 5216
NDUFAF1 8607 8609
NDUFAF2 3829 2032
NDUFAF3 5144 7907
NDUFAF4 -2156 -10818
NDUFAF5 -8081 -6902
NDUFAF6 3362 -4662
NDUFAF7 184 3856
NDUFB1 5797 9160
NDUFB10 3663 6774
NDUFB11 -1387 2753
NDUFB2 -8409 1299
NDUFB3 7747 9233
NDUFB4 3456 5084
NDUFB5 6803 3064
NDUFB6 3065 5013
NDUFB7 -3596 5174
NDUFB8 -3877 3981
NDUFB9 7171 9130
NDUFC1 1585 7243
NDUFC2 1951 7994
NDUFS1 5966 7204
NDUFS2 2756 7134
NDUFS3 -3624 3634
NDUFS4 5763 3776
NDUFS5 3517 7380
NDUFS6 -475 6671
NDUFS7 -3336 4665
NDUFS8 -3148 2931
NDUFV1 -10123 -8972
NDUFV2 6284 3782
NDUFV3 6951 5409
NEU1 9336 9571
NEU3 -1390 -1896
NFS1 2075 7621
NFYA 3506 4239
NFYB -726 -10664
NFYC 6238 8722
NHLRC1 -8568 -610
NME1 2317 2026
NME2 2395 3054
NME3 -3887 1742
NME4 5756 5118
NMNAT1 9482 10033
NMNAT2 9877 10130
NMNAT3 -6101 694
NMRAL1 -10214 -1057
NMRK1 112 -3517
NNT 2682 5607
NOS3 5934 -5046
NOSIP 123 -7764
NPAS2 3422 -335
NQO1 -3007 -1149
NQO2 9379 8979
NR1D1 -5157 -8776
NR1H2 4003 8448
NR1H3 -8939 2196
NRF1 -10463 -30
NSDHL 897 5839
NT5C -10218 -4283
NT5C1B -2355 -9145
NT5C2 9270 9172
NT5C3A 7678 3210
NT5E -2269 -7078
NT5M 6357 6624
NUBP1 2823 5380
NUBP2 -9134 -5144
NUBPL -8291 -10942
NUDT1 -8951 3346
NUDT11 -10658 -6168
NUDT12 3042 -3026
NUDT13 2331 -6558
NUDT15 8562 -6932
NUDT16 9089 9729
NUDT18 -5124 6005
NUDT19 5969 7625
NUDT3 6863 6507
NUDT4 8948 7160
NUDT5 -1107 -745
NUDT7 3319 956
NUDT9 7708 4428
NUP107 -4463 -10317
NUP133 -4339 -4616
NUP153 -7195 -2408
NUP155 -4644 -9292
NUP160 -2518 -10020
NUP188 -9467 -9810
NUP205 -8533 -9667
NUP210 -10480 -5943
NUP214 8588 8152
NUP35 -4281 -10256
NUP37 3188 3613
NUP42 1567 -5400
NUP43 -55 -10161
NUP50 6614 4617
NUP54 2794 -9194
NUP58 9637 9212
NUP62 3053 1921
NUP85 1119 -2732
NUP88 -7116 -10078
NUP93 -9095 -8944
NUP98 208 4310
OAT 9400 9173
OAZ1 9446 9881
OAZ2 9433 9082
OAZ3 1510 -6113
OCRL 7540 6631
ODC1 5919 2879
OGDH -4891 6549
OPLAH 10032 9930
ORMDL1 -647 -5722
ORMDL2 -1137 7315
ORMDL3 -9307 -7231
OSBP -4943 1320
OSBPL10 764 -3626
OSBPL1A -7890 -3076
OSBPL2 -9184 6634
OSBPL3 -10108 -10957
OSBPL5 -11168 -8140
OSBPL6 7361 3374
OSBPL7 -9913 -10464
OSBPL8 8564 6575
OSBPL9 6176 6694
OXCT1 -8779 -10705
OXCT2 173 -2803
PAICS 6998 -9059
PANK1 3275 -1021
PANK2 8902 7971
PANK3 6511 2041
PANK4 -9550 -2144
PAOX -9708 -7914
PAPSS1 9369 9581
PAPSS2 -10676 2940
PARP10 -9335 -4173
PARP14 -8685 -10901
PARP16 -10582 -9753
PARP4 13 6081
PARP6 -4204 -3339
PARP8 -6730 -6159
PARP9 1298 -3808
PC 9686 9800
PCBD1 5109 8138
PCCA -5749 -6966
PCCB -7266 -3557
PCK2 -6122 2900
PCTP 9909 9764
PCYT1A 4565 7128
PCYT1B 8218 8793
PCYT2 -10691 -6884
PDHA1 -4916 117
PDHB 6533 3960
PDHX 7203 3502
PDK1 8540 1574
PDK2 -9124 -4346
PDK3 1125 4803
PDK4 7304 6115
PDP1 2704 -5372
PDP2 -8972 -9565
PDPR -6968 -5062
PDSS1 7333 7901
PDSS2 7117 6922
PDXK 9135 9342
PDZD11 -9036 -585
PECR 9763 9101
PEMT 6341 2345
PEX11A -10460 -2960
PFAS -7982 -10250
PFKFB1 -7223 -6744
PFKFB2 -9116 8194
PFKFB3 7624 9236
PFKFB4 9668 9897
PFKL -4964 514
PFKM 4047 -1416
PFKP -6877 899
PGAM1 9980 9987
PGD 10065 10089
PGK1 9349 8950
PGLS 2615 7428
PGM1 -2421 7047
PGM2 9878 9866
PGM2L1 -960 3787
PGP -4288 3583
PGS1 9084 9373
PHGDH 3743 2995
PHKA2 8133 9490
PHKB 9693 9132
PHKG1 -7098 -6724
PHKG2 -58 3328
PHOSPHO1 -3118 4072
PHYH 1932 -3057
PHYKPL 4952 7575
PI4K2A -10792 2983
PI4K2B -7633 -10842
PI4KA -7058 2288
PI4KB -6243 778
PIAS4 -1432 8309
PIK3C2A 1258 -5821
PIK3C2B -9423 -10059
PIK3C2G 692 2494
PIK3C3 6605 573
PIK3CA 6889 4182
PIK3CB 9838 9248
PIK3CD 82 7288
PIK3CG -9742 5545
PIK3R1 -7197 -8942
PIK3R2 2459 5820
PIK3R3 -11107 -8159
PIK3R4 -267 -2209
PIK3R5 -9700 3911
PIK3R6 8267 7206
PIKFYVE 4628 3510
PIP4K2A -8599 2837
PIP4K2B -7642 -3179
PIP4K2C -10764 -5694
PIP5K1A 6224 6407
PIP5K1B 5094 7192
PIP5K1C -4447 6435
PIPOX -7738 -4039
PISD 9461 9362
PITPNB 14 -5378
PITPNM1 -3031 7875
PITPNM2 -6691 -2278
PITPNM3 -3701 -2129
PKM 9904 9954
PLA2G10 996 -4331
PLA2G12A 8347 5019
PLA2G15 8284 9631
PLA2G2D -3039 -4555
PLA2G4A 9622 10024
PLA2G4B -1937 -7077
PLA2G4C -1895 -3087
PLA2G4D 2605 422
PLA2G6 -10753 -10993
PLA2R1 2526 3806
PLAAT1 7523 6061
PLAAT2 4649 -1451
PLAAT3 -10520 -2397
PLAAT4 -10969 -11040
PLB1 9997 10127
PLBD1 10121 10138
PLCB1 1989 1657
PLCB2 2249 5858
PLCB3 8806 9909
PLCD1 -8899 -5500
PLCD3 9756 9938
PLCD4 -6501 -10426
PLCE1 64 -7794
PLCG1 -6360 -11043
PLCG2 -4618 6826
PLCH1 -4360 3907
PLCH2 -10230 -11120
PLD1 9826 9945
PLD2 7087 7779
PLD3 8640 7098
PLD4 -11266 -11216
PLD6 3638 -7258
PLEKHA1 -10730 -11019
PLEKHA2 -5997 2173
PLEKHA3 -5088 -1720
PLEKHA4 -1073 2011
PLEKHA5 -5362 -2954
PLEKHA6 -2691 -787
PLEKHA8 2578 -3278
PLIN1 -6629 -678
PLIN2 6368 9669
PLIN3 9856 10099
PLPP1 6735 -9356
PLPP2 5168 193
PLPP3 6276 9462
PLPP6 -9831 -6651
PM20D1 -6198 -9635
PMVK -1803 5434
PNMT -4884 1572
PNP 9167 8393
PNPLA2 9239 9613
PNPLA4 -5903 430
PNPLA6 -1244 8600
PNPLA7 -1935 -7059
PNPLA8 9265 7482
PNPO -3471 -4515
PODXL2 -8866 -6684
POLD1 609 1677
POM121 -8969 -3230
POM121C -9525 -1010
POMC 1489 3391
PON2 -4434 -4773
POR 6049 9478
PPA1 7407 -715
PPA2 3091 2489
PPARA -791 2682
PPARD -2381 -5446
PPARG 10111 10137
PPARGC1A 7923 1692
PPARGC1B -2475 -4269
PPAT -2697 -11066
PPCDC -6659 2645
PPCS 7337 6049
PPIP5K1 -9114 -9386
PPIP5K2 8325 5657
PPM1K -9336 -10615
PPM1L -9625 3554
PPOX -9620 -9769
PPP1CA -5695 6595
PPP1CB 8657 6666
PPP1CC 9200 4868
PPP2CA 8810 8328
PPP2CB 8482 7631
PPP2R1A -3087 6994
PPP2R1B 2503 437
PPP2R5D -6508 4985
PPT1 9946 8681
PPT2 -10048 -9076
PRELP 3029 -3227
PRKAB2 -3794 -7488
PRKACA 9885 10068
PRKACB -9852 -10936
PRKAG2 7892 7
PRKAR1A 8455 9570
PRKAR1B 8879 7874
PRKAR2A 3755 7093
PRKAR2B 7943 7189
PRKCA 2473 1229
PRKD2 -10545 -3285
PRKD3 1523 2383
PRKG2 -7602 -7604
PRODH -7166 -8955
PRPS1 -10387 -10439
PRPS2 8155 2205
PRSS1 -9026 -8646
PRXL2B 728 -6849
PSAP 7519 7770
PSAT1 8012 6463
PSMA1 8278 7406
PSMA2 5830 5666
PSMA3 4646 -7621
PSMA4 3950 -1036
PSMA5 -2119 -3983
PSMA6 6893 5865
PSMA7 3550 8554
PSMB1 3915 4224
PSMB10 -7878 -1272
PSMB2 2664 4928
PSMB3 4971 8382
PSMB4 -3175 4911
PSMB5 6561 9138
PSMB6 1312 8784
PSMB7 8034 9051
PSMB8 -4481 75
PSMB9 -9105 -10433
PSMC1 6759 7782
PSMC2 -2524 4517
PSMC3 -4971 4984
PSMC4 -10757 -336
PSMC5 -3424 2764
PSMC6 8812 6000
PSMD1 7679 7587
PSMD10 2067 2450
PSMD11 6914 6824
PSMD12 9011 5710
PSMD13 3157 7205
PSMD14 2891 3041
PSMD2 4352 8396
PSMD3 -2243 6367
PSMD4 6858 9449
PSMD5 2770 4781
PSMD6 8841 8304
PSMD7 6534 6147
PSMD8 739 7117
PSMD9 3580 9001
PSME1 -7256 -7913
PSME2 -5548 -10355
PSME3 9120 8239
PSME4 -5205 -3127
PSMF1 6709 6770
PSPH 7084 6594
PSTK -6683 -9506
PTDSS1 8097 6669
PTDSS2 6491 6099
PTEN 9191 8752
PTGDS -10836 -6070
PTGES -5184 6141
PTGES2 -6197 -3780
PTGES3 8385 2175
PTGR1 9237 9969
PTGR2 2097 1589
PTGS1 9559 8597
PTGS2 6044 3823
PTPMT1 2320 2876
PTPN13 -9422 -7282
PTS 1039 -2197
PUDP 9843 7809
PXMP2 -941 4791
PYCR1 9294 5464
PYCR2 -6278 1740
PYGB -5192 3500
PYGL 10071 9926
PYGM -2970 -4197
QARS1 -4041 2620
QDPR -3796 -3344
QPRT -10904 -9973
RAB14 8215 7014
RAB4A 9473 7027
RAB5A 8478 6815
RAE1 4777 6291
RAN -2391 -4763
RANBP2 4453 -2222
RAP1A 8688 6973
RAPGEF3 1224 -2066
RARS1 1042 -3848
RBKS -7050 1601
RDH11 8205 6140
RETSAT -342 2405
RFK 7072 2157
RGL1 7936 8025
RHCE 7738 5055
RHD 5210 3212
RIDA 8574 3783
RIMKLA -4718 -113
RIMKLB -7095 -10269
RNLS 677 5127
RORA -10511 -10952
RPE -569 4180
RPIA 4409 1808
RPL10 -5353 -4722
RPL10A -1883 -6533
RPL11 -1931 -5590
RPL12 -4453 -5830
RPL13 -1749 -2925
RPL13A -5236 -7060
RPL14 -3538 -6408
RPL15 2144 -270
RPL17 -2803 -4216
RPL18 -2407 -4107
RPL18A -4338 -4740
RPL19 -5605 -4047
RPL21 -2408 -6412
RPL22 1616 -5576
RPL22L1 3994 -3396
RPL23 -353 -2321
RPL23A -4695 -9373
RPL24 -3568 -4504
RPL26 -4494 -4767
RPL26L1 6548 7865
RPL27 -3684 -361
RPL27A -5814 -4093
RPL28 -2567 614
RPL29 -2138 -1913
RPL3 -6886 -7461
RPL30 -5225 -5596
RPL31 -2656 -3267
RPL32 -3094 -6607
RPL34 -2097 -7114
RPL35 -8453 -5007
RPL35A -2671 -5323
RPL36 -6761 -2662
RPL36A -5740 -5975
RPL36AL -1773 1920
RPL37 -8529 -2184
RPL37A -5802 -727
RPL38 -7075 -2793
RPL39 -983 -3231
RPL39L -10310 -4203
RPL4 2174 -3722
RPL41 -7404 -3692
RPL5 2979 -5487
RPL6 3510 -3949
RPL7 3811 -2799
RPL7A -2851 -1500
RPL8 -4534 1780
RPL9 -167 -2256
RPLP0 3127 -1531
RPLP1 -2483 2491
RPLP2 -7230 -4974
RPS10 -5228 -3784
RPS11 -7652 -3921
RPS12 -4698 -5458
RPS13 3315 -2060
RPS14 -6862 -2786
RPS15 -4712 -988
RPS15A -3464 -4486
RPS16 -3811 -3249
RPS17 -6899 -3309
RPS18 -6859 -6415
RPS19 -5797 -5539
RPS2 -6072 -1316
RPS20 -6536 -7674
RPS21 -4436 -2455
RPS23 -1921 -5872
RPS24 3926 -838
RPS25 -1359 -6741
RPS26 -1177 -1112
RPS27 -9041 -7909
RPS27A -3555 -7070
RPS27L 5307 1458
RPS28 -5391 -2679
RPS29 -8497 -5396
RPS3 -4098 -4595
RPS3A 3428 -6271
RPS4X -1869 -6447
RPS4Y1 5773 -56
RPS5 -4290 -4473
RPS6 -1613 -5951
RPS7 -1789 -4131
RPS8 2338 -2478
RPS9 3357 6145
RPSA -2286 -5572
RRM1 -5539 -10594
RRM2 1990 -1776
RRM2B 9101 6108
RTEL1 -8739 1791
RUFY1 6901 6963
RXRA 6327 8932
RXRB -7622 2709
SACM1L -8224 -5336
SAMD8 9137 7361
SAMHD1 7413 6999
SAR1B 8795 5984
SARDH -5678 -9727
SARS1 -7170 -134
SAT1 5084 5743
SBF1 -10462 -5210
SBF2 9757 9727
SC5D 3897 -4878
SCAP -6407 344
SCD 6578 3616
SCD5 -10066 -2380
SCLY -3206 -7232
SCO1 -5473 -7347
SCO2 1689 -5906
SCP2 6933 4053
SDC2 7232 4710
SDC3 3723 2630
SDC4 6516 7115
SDHA -7274 -801
SDHB 5535 8589
SDHC 8009 8911
SDHD 8418 6412
SDS -8923 -1542
SDSL -4231 5010
SEC13 2125 6861
SEC23A 8776 6905
SEC24A 8318 7788
SEC24B 1663 5398
SEC24C -9662 3561
SEC24D 8017 8795
SECISBP2 -3771 -10997
SEH1L 7189 -8511
SELENOI -4666 -10648
SEM1 993 5942
SEPHS2 6318 8603
SEPSECS -6441 -10823
SERINC1 6193 5918
SERINC2 9032 9321
SERINC3 3583 7986
SERINC4 2806 -2518
SERINC5 3637 -7064
SGMS1 9171 9489
SGMS2 9876 9677
SGPL1 -5878 6696
SGPP1 -11051 -9436
SGPP2 -4526 -8818
SGSH 6255 6622
SHMT1 -2256 774
SHMT2 -8103 -1490
SHPK -2824 521
SIN3A -9037 -7770
SIN3B -4559 -1682
SLC10A1 4523 -3989
SLC16A1 7992 3127
SLC16A3 7685 9834
SLC16A8 -6480 3682
SLC19A1 9283 9332
SLC19A2 -3481 -2334
SLC19A3 -5301 566
SLC22A1 -2572 6250
SLC22A5 8129 6640
SLC23A1 1430 -5632
SLC23A2 -4985 -414
SLC25A1 -843 6264
SLC25A10 -9533 -7148
SLC25A11 2728 8568
SLC25A12 -6088 -358
SLC25A13 1053 210
SLC25A14 373 -5018
SLC25A15 -9254 -4120
SLC25A16 6226 -962
SLC25A17 -7117 -9512
SLC25A19 5200 1293
SLC25A20 -6402 7153
SLC25A21 5477 -2778
SLC25A27 4811 -7088
SLC25A28 -4944 297
SLC25A32 3908 -9796
SLC25A37 10069 9899
SLC25A44 6490 8342
SLC26A1 -4438 -7156
SLC26A2 -2767 -643
SLC27A1 9371 8373
SLC27A2 6501 -6385
SLC27A3 -3668 1756
SLC27A5 -5914 -8
SLC2A1 -11011 -6196
SLC2A3 9614 9612
SLC35B2 -9784 -6175
SLC35B3 7339 5568
SLC35D1 -5746 -4085
SLC35D2 8843 7622
SLC36A4 8563 7899
SLC37A1 -6350 -1812
SLC37A2 1956 3314
SLC37A4 -5208 -4132
SLC3A2 200 6877
SLC44A1 9313 9124
SLC44A2 -8609 5338
SLC44A5 -358 -4399
SLC46A1 589 2726
SLC52A1 1504 -8046
SLC52A2 -8504 712
SLC5A5 4358 -8309
SLC5A6 -1016 -4649
SLC6A12 5563 3015
SLC6A8 9954 8846
SLC7A5 -2245 4782
SLC9A1 3224 9393
SLCO2B1 8444 8881
SMARCD3 9870 8230
SMOX 4775 7991
SMPD1 -9838 5204
SMPD2 -7187 6202
SMPD3 -11070 -10458
SMPD4 -10327 -8352
SMS 9397 5103
SORD 9477 8949
SP1 8282 9168
SPHK1 8030 8271
SPHK2 -5524 6361
SPNS2 5814 5993
SPR 7379 7833
SPTLC1 9241 8962
SPTLC2 9108 9317
SPTLC3 3877 675
SPTSSA 7995 3610
SPTSSB -10164 -4445
SQLE -2471 5367
SRD5A1 9492 7352
SRD5A3 3417 4347
SREBF1 8758 5979
SREBF2 5424 7541
SRM 451 -7384
SRR 1257 -3435
ST3GAL1 -6884 -3859
ST3GAL2 7832 9657
ST3GAL3 2775 828
ST3GAL4 -9921 7993
ST3GAL6 9317 5155
ST6GALNAC6 -10863 -9916
STAB2 7035 5388
STAR -3804 76
STARD10 5224 5133
STARD3 -7867 7146
STARD3NL 6126 8112
STARD4 -448 -3799
STARD5 -10081 3667
STARD7 5361 4192
STK11 -70 4172
STS 1348 5281
STX1A -9454 1322
STXBP1 603 -7996
SUCLA2 9607 5920
SUCLG1 6101 6256
SUCLG2 -763 -4755
SULT1A1 7707 8712
SULT1A2 -207 -4052
SULT1A3 4142 4659
SULT1A4 6409 5670
SULT1B1 9897 10014
SULT1C2 1027 -1456
SULT2B1 -4343 -7662
SUMF1 9162 9651
SUMF2 -10998 -8612
SUMO2 6089 5153
SUOX -4061 7493
SURF1 1537 4399
SYNJ1 5518 6949
SYNJ2 -6592 -7005
SYT5 4099 6191
TACO1 1415 5941
TALDO1 10039 9995
TAZ 406 5258
TBL1X 8359 8499
TBL1XR1 4714 4779
TBXAS1 9105 9461
TCN1 8724 3700
TCN2 9169 9144
TECR -8480 -6099
TECRL -2441 2970
TGS1 -141 -4762
THEM4 -5349 -11202
THEM5 -6790 -7616
THRAP3 -3609 3263
THTPA -7396 860
TIAM2 -10122 -8001
TIMMDC1 7612 6926
TK1 486 5978
TK2 9726 9813
TKFC 5127 5512
TKT 9790 9907
TM7SF2 -7355 -4373
TMEM126B -2793 -7417
TMEM86B 1635 4473
TMLHE 7205 8685
TNFAIP8 4860 -1256
TNFAIP8L1 -9011 -7251
TNFAIP8L2 4641 6495
TNFRSF21 -11248 -7530
TPH1 -2180 -9746
TPH2 2016 3522
TPI1 3487 7979
TPK1 -4767 -289
TPMT 5197 4466
TPO 7263 -6039
TPR -1066 -7983
TPST1 9124 9903
TPST2 -8995 8264
TRAP1 -7465 -10079
TRIB3 -7572 -1651
TRMT112 -4210 3619
TSPO 9681 9965
TSPOAP1 -10988 -7555
TST 7774 8272
TSTD1 -7709 -6353
TTPA -838 3345
TXN 8317 8729
TXN2 101 6323
TXNRD1 8327 8699
TYMP 4150 3100
TYMS 4782 -1548
UBA52 -1875 3023
UBB 8251 6157
UBC -1915 5825
UBE2I -4201 2754
UBIAD1 -6009 -9842
UCK1 -5393 7218
UCK2 -10727 -2882
UCKL1 -2117 -5654
UCP2 -6588 4309
UCP3 -8598 -8396
UGCG 2716 5849
UGDH 5868 3938
UGP2 9020 6649
UGT1A1 -1062 2528
UGT2B11 24 -8896
UGT8 -3604 -4150
UMPS -4083 -9494
UPB1 1986 7222
UPP1 8940 9096
UQCR10 -3040 6629
UQCR11 4762 8027
UQCRB 4393 4494
UQCRC1 6287 8827
UQCRC2 8613 4784
UQCRFS1 5452 7178
UQCRH 7911 8678
UQCRQ -608 4630
UROD -606 6562
UROS -8670 -9640
UST -10604 -10167
VAC14 -6990 4152
VAMP2 -9677 -10779
VAPA 9732 9322
VAPB 5092 2395
VCAN 10068 10125
VDAC1 6643 4063
VDR 7908 9387
VKORC1 7116 6773
VKORC1L1 5659 4491
VNN1 9174 9668
VNN2 9583 9574
WASL 899 1391
XYLB -8542 -8092
XYLT1 -10080 -536
XYLT2 -7281 -133
ZDHHC21 2487 -7571



Metabolism of proteins

Metabolism of proteins
metric value
setSize 1706
pMANOVA 1.53e-28
p.adjustMANOVA 2.61e-26
s.dist 0.191
s.low.CRP 0.0967
s.high.CRP 0.165
p.low.CRP 3.22e-11
p.high.CRP 1.16e-29




Top 20 genes
Gene low CRP high CRP
CSF2RA 10124 10140
ADAMTS2 10123 10126
PPARG 10111 10137
FAM20A 10078 10142
CTSA 10083 10131
VCAN 10068 10125
NPL 10063 10123
F5 10084 10070
ASGR2 10000 10129
RAB13 10014 10088
BST1 10108 9972
FBXO9 10081 9997
RAB32 10006 10036
KIF13A 9932 10069
SOCS3 9830 10110
RAB31 9956 9895
RHOT1 10010 9811
XRN2 9895 9902
FAM20C 9723 10066
CKAP4 10101 9674

Click HERE to show all gene set members

All member genes
low CRP high CRP
AAAS -8564.0 -4273.0
AARS1 -3033.0 -7175.0
AARS2 -10032.0 -9696.0
ABCA3 -10824.0 -8696.0
ACADVL 8805.0 8687.0
ACE 2264.0 -10895.0
ACTB 9310.0 9714.0
ACTL6A -1737.0 -5002.0
ACTR10 8589.0 7569.0
ACTR1A -2833.0 8680.0
ACTR5 -9698.0 -8731.0
ACTR8 -8619.0 1129.0
ADAM10 9314.0 9481.0
ADAMTS1 -11098.0 -5754.0
ADAMTS10 -10752.0 -8150.0
ADAMTS13 -3300.0 -3397.0
ADAMTS14 -10382.0 -1142.0
ADAMTS16 -5113.0 -7987.0
ADAMTS17 1930.0 -5706.0
ADAMTS2 10123.0 10126.0
ADAMTS4 -10045.0 -8251.0
ADAMTS5 4721.0 -5392.0
ADAMTS6 -6097.0 -5389.0
ADAMTSL3 2431.0 443.0
ADAMTSL4 7713.0 8020.0
ADAMTSL5 462.0 -10240.0
ADD1 -5862.0 7957.0
ADORA2A -4195.0 4298.0
ADORA2B 8620.0 9622.0
ADRA2A -416.0 4269.0
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AGBL5 6194.0 3218.0
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ALB 1254.0 3551.0
ALG1 -9753.0 -1781.0
ALG10 -6726.0 -6482.0
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ANKRD28 -5795.0 -3898.0
ANKRD9 8481.0 8619.0
ANO8 6301.0 6525.0
ANPEP 9881.0 9819.0
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APC 3083.0 3959.0
APEH -8617.0 5030.0
APH1A -3379.0 6321.0
APH1B 6306.0 6678.0
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AR 5214.0 4808.0
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ARF3 5651.0 9049.0
ARF4 9859.0 9444.0
ARF5 5736.0 9180.0
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ARL2 -5078.0 2617.0
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ARSJ -1176.0 -6399.0
ARSK -8263.0 -10357.0
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ASB6 -7877.0 2463.0
ASB7 7450.0 6094.0
ASB8 823.0 6079.0
ASB9 4472.0 -207.0
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ASGR2 10000.0 10129.0
ASNS -2039.0 -9431.0
ASXL1 -6957.0 -9295.0
ASXL2 -1697.0 3477.0
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ATF4 7241.0 6281.0
ATF6 8612.0 9198.0
ATP6AP2 9221.0 7743.0
ATP6V0D1 9444.0 9942.0
ATXN3 5521.0 599.0
ATXN7 6293.0 -3592.0
AURKA -542.0 4483.0
AURKAIP1 1685.0 7421.0
AURKB -4097.0 3408.0
AXIN1 -10901.0 -2157.0
AXIN2 1014.0 -9374.0
B2M -4257.0 -4660.0
B3GALNT2 765.0 622.0
B3GLCT -10606.0 -8784.0
B3GNT2 5152.0 5953.0
B3GNT4 -8399.0 -9205.0
B3GNT5 10030.0 8205.0
B3GNT7 -11219.0 -9428.0
B3GNT8 9251.0 9421.0
B3GNT9 4813.0 -5292.0
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B4GALT2 -7253.0 -2349.0
B4GALT3 -9162.0 -7981.0
B4GALT4 -9971.0 3971.0
B4GALT5 8862.0 9469.0
B4GALT6 -10936.0 -1047.0
B4GAT1 -4385.0 -4229.0
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BACE1 7754.0 1681.0
BAP1 -8830.0 5447.0
BARD1 -8030.0 184.0
BCL10 6467.0 6003.0
BECN1 6040.0 6760.0
BET1 7030.0 -4395.0
BET1L -7832.0 -2582.0
BGLAP 819.0 -1590.0
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BIRC3 -2270.0 -11079.0
BIRC5 2725.0 4169.0
BLM -2847.0 -3960.0
BMI1 -3862.0 -8689.0
BRCA1 8071.0 6505.0
BRCC3 7957.0 6103.0
BST1 10108.0 9972.0
BTBD1 6622.0 1719.0
BTBD6 -7724.0 -284.0
BTRC -6845.0 -441.0
C1GALT1 1726.0 -3586.0
C1GALT1C1 8882.0 8311.0
C3 -11179.0 -10489.0
C4A 5060.0 4740.0
CALB1 3370.0 -5190.0
CALM1 -6645.0 1321.0
CALR 6685.0 6374.0
CALU 9106.0 7766.0
CAMKMT 6048.0 -981.0
CAND1 3497.0 -7234.0
CANX 6838.0 5751.0
CAPZA1 8666.0 8511.0
CAPZA2 9698.0 8474.0
CAPZB 6100.0 8926.0
CARS1 3060.0 8714.0
CARS2 7226.0 7860.0
CASP8AP2 -565.0 -10849.0
CBX2 -6781.0 -1304.0
CBX4 -7121.0 4998.0
CBX5 -4225.0 -8724.0
CBX8 6588.0 5926.0
CCDC22 1981.0 8158.0
CCDC59 3299.0 -5203.0
CCDC8 6938.0 -2578.0
CCL2 -10976.0 -11174.0
CCNA1 1826.0 474.0
CCNA2 1795.0 1560.0
CCNE1 -8303.0 -11081.0
CCNE2 6498.0 5473.0
CCNF -10194.0 -4195.0
CCP110 5497.0 1580.0
CCT2 1978.0 -8922.0
CCT3 -1967.0 394.0
CCT4 5187.0 393.0
CCT5 8265.0 6849.0
CCT6A 5343.0 -532.0
CCT6B -10405.0 -8293.0
CCT7 -4580.0 811.0
CCT8 8723.0 5878.0
CD109 5339.0 4477.0
CD52 -5003.0 -406.0
CD55 9326.0 9842.0
CD59 4075.0 5772.0
CDC20 -74.0 5136.0
CDC25A 3970.0 2814.0
CDC34 8212.0 9329.0
CDC73 5065.0 5233.0
CDCA8 -4836.0 412.0
CDK1 4994.0 -360.0
CDKN2A -3659.0 -3958.0
CEBPB 4182.0 9158.0
CEBPG 7398.0 5292.0
CES1 10060.0 8572.0
CETN2 6907.0 5515.0
CFP 6744.0 8615.0
CHCHD1 5844.0 8369.0
CHD3 -9446.0 -6383.0
CHM 3845.0 3159.0
CHML 5118.0 -3431.0
CHST10 -11043.0 -8384.0
CHST8 2634.0 6673.0
CISH 9673.0 299.0
CKAP4 10101.0 9674.0
CLSPN 4958.0 3125.0
CMAS 9548.0 8906.0
CNIH1 9316.0 7116.0
CNIH2 701.0 601.0
CNIH3 -8173.0 -6989.0
COG1 -10399.0 -10838.0
COG2 -1210.0 -5915.0
COG3 3891.0 -5333.0
COG4 -4813.0 2002.0
COG5 1617.0 -3368.0
COG6 1512.0 -6280.0
COG7 2191.0 6149.0
COG8 -2814.0 2839.0
COL7A1 3993.0 7683.0
COMMD1 6175.0 5987.0
COMMD10 7526.0 3203.0
COMMD2 5023.0 3219.0
COMMD3 1068.0 -670.0
COMMD4 -7833.0 871.0
COMMD5 3387.0 6513.0
COMMD6 942.0 -555.0
COMMD7 979.0 6845.0
COMMD8 8929.0 6796.0
COMMD9 8869.0 7706.0
COPA 7617.0 9591.0
COPB1 8213.0 7283.0
COPB2 8531.0 8034.0
COPE 365.0 8719.0
COPG1 2542.0 9195.0
COPG2 7905.0 8313.0
COPS2 8864.0 5037.0
COPS3 7364.0 5716.0
COPS4 1748.0 2715.0
COPS5 3882.0 5135.0
COPS6 -3920.0 4485.0
COPS7A 1707.0 8090.0
COPS7B -9179.0 -6481.0
COPS8 -1206.0 -8494.0
COPZ1 2549.0 5017.0
COPZ2 -9229.0 -9247.0
CP -4947.0 388.0
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CPM 7659.0 7193.0
CREB3 -8108.0 1395.0
CREB3L2 -3363.0 1265.0
CREB3L4 -10251.0 -4851.0
CREBBP -4951.0 6023.0
CREBRF 6853.0 -3322.0
CRHR2 -7107.0 -2145.0
CSF1 196.0 -1673.0
CSF2RA 10124.0 10140.0
CSF2RB 7899.0 7940.0
CSNK1D -10030.0 6117.0
CSNK2A1 3192.0 8248.0
CSNK2A2 6050.0 7886.0
CSNK2B 1222.0 5287.0
CST3 1960.0 3081.0
CTBP1 -10319.0 2597.0
CTDSP2 3312.0 7159.0
CTNNB1 3201.0 7613.0
CTR9 2564.0 4136.0
CTSA 10083.0 10131.0
CTSC -7528.0 5285.0
CTSD 9620.0 10120.0
CTSG 9156.0 1689.0
CTSH 6991.0 6545.0
CTSZ 8972.0 9860.0
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CUL2 6801.0 1682.0
CUL3 7151.0 7368.0
CUL4A 417.0 -2398.0
CUL4B 4392.0 3352.0
CUL5 7502.0 -2980.0
CUL7 -8296.0 2248.0
CUL9 -6452.0 -2962.0
CXCL8 3332.0 -907.0
CXXC1 -3011.0 1008.0
CYLD 2995.0 -11046.0
DAD1 5534.0 6325.0
DAG1 -8464.0 -2147.0
DAP3 1459.0 96.0
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DARS2 -6880.0 579.0
DAXX -10506.0 -3361.0
DCAF10 6518.0 5106.0
DCAF11 -9260.0 2252.0
DCAF13 -3380.0 -2910.0
DCAF16 -7938.0 -10787.0
DCAF17 -6900.0 -10369.0
DCAF4 -7031.0 -10627.0
DCAF5 -10760.0 -125.0
DCAF6 8820.0 8847.0
DCAF7 -4647.0 2263.0
DCAF8 -8640.0 -7396.0
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DCTN1 -5984.0 7873.0
DCTN2 8504.0 10012.0
DCTN3 325.0 7904.0
DCTN4 7967.0 9572.0
DCTN5 -7505.0 664.0
DCTN6 7871.0 7759.0
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DCUN1D3 1597.0 5396.0
DCUN1D4 3074.0 -10782.0
DCUN1D5 3584.0 1371.0
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DDB1 -2944.0 5557.0
DDB2 -9012.0 -10384.0
DDIT3 4098.0 5390.0
DDOST 459.0 8249.0
DDX11 -4069.0 -5527.0
DDX17 -2678.0 -5554.0
DDX5 -8723.0 -7926.0
DDX58 -10158.0 -10278.0
DERL1 -8912.0 -3885.0
DERL2 4947.0 3337.0
DHDDS -7112.0 3558.0
DHPS -2392.0 3110.0
DIS3 4126.0 -5938.0
DNAJB11 7184.0 5394.0
DNAJB9 4812.0 -169.0
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DNAJC3 9077.0 8882.0
DNMT1 -10726.0 -10916.0
DNMT3A -3948.0 -310.0
DNMT3B 5487.0 4173.0
DOHH -3151.0 1163.0
DOLK -6603.0 967.0
DOLPP1 3438.0 3524.0
DPAGT1 6056.0 1306.0
DPH1 -8051.0 -10630.0
DPH2 -7140.0 -9731.0
DPH3 9097.0 7392.0
DPH5 3102.0 395.0
DPH6 -967.0 -8206.0
DPH7 -9088.0 -8668.0
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DTL 2723.0 -661.0
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DYNC1I1 7141.0 2722.0
DYNC1I2 8160.0 8196.0
DYNC1LI1 7894.0 6997.0
DYNC1LI2 3494.0 5636.0
DYNLL1 6026.0 6499.0
DYNLL2 -6325.0 -225.0
EARS2 -10226.0 -10050.0
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EDEM2 8210.0 9514.0
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EIF5A 1424.0 1809.0
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ELOB 4867.0 8716.0
ELOC 6598.0 8484.0
ENAM 731.0 -2171.0
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EP300 4311.0 7552.0
EPAS1 5959.0 8551.0
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ERAL1 -6124.0 -257.0
ERCC8 2277.0 4188.0
ERN1 -10049.0 -5399.0
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ESR1 -6046.0 -8495.0
ETF1 8721.0 7223.0
ETFB 6243.0 9120.0
ETFBKMT 5689.0 1933.0
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F8 7498.0 7167.0
FAM20A 10078.0 10142.0
FAM20C 9723.0 10066.0
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FARSA -3958.0 4883.0
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FAU -5297.0 2810.0
FBN1 5230.0 4463.0
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FBXL13 2462.0 5869.0
FBXL14 -6789.0 -2829.0
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FBXO32 -9356.0 -10029.0
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FBXO44 -7880.0 -8023.0
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FBXW9 -10047.0 -416.0
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FEM1C 5709.0 4915.0
FFAR4 6510.0 1912.0
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FKBP8 9424.0 8644.0
FKBP9 8370.0 9041.0
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FN3K 6996.0 2744.0
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FOLR2 2768.0 -6707.0
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FOXK2 -2626.0 6074.0
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FPGT 8997.0 6942.0
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FURIN 8111.0 10053.0
FUT8 -7539.0 -7706.0
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GALNT11 -4476.0 780.0
GALNT12 -4955.0 -9921.0
GALNT14 8541.0 9404.0
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GALNT2 8571.0 9697.0
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GALNT9 -2617.0 -10483.0
GAN 203.0 -1098.0
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GAS6 6462.0 9517.0
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GATA6 -10906.0 -9307.0
GBA 8941.0 9735.0
GBF1 -8933.0 1807.0
GCNT1 8143.0 9126.0
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GGCX 4204.0 6743.0
GHRL -9172.0 -6917.0
GLB1 9091.0 9091.0
GMDS 4877.0 5289.0
GMPPA 1299.0 5440.0
GMPPB -7578.0 -3166.0
GNAI1 6562.0 2097.0
GNAI2 5861.0 9258.0
GNAI3 9178.0 7726.0
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GNB3 7806.0 -8406.0
GNB4 9340.0 6537.0
GNB5 6182.0 -475.0
GNE -484.0 -3839.0
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GNG8 4092.0 4604.0
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GNPNAT1 4439.0 -10903.0
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GOLM1 -6550.0 -4069.0
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GPS1 -8718.0 1571.0
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GSN 9281.0 9397.0
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GZMH -10934.0 -6246.0
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H2AW -10705.0 -7332.0
H2AZ1 1779.0 7321.0
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H2BC15 3036.0 6455.0
H2BC17 7882.0 7312.0
H2BC18 4771.0 8130.0
H2BC21 9852.0 9656.0
H2BC4 7156.0 7805.0
H2BC5 7596.0 8773.0
H2BC9 7965.0 4715.0
H2BU1 -6349.0 -3895.0
H3-3A 9297.0 9034.0
H3C15 5262.5 7402.5
HARS1 -6476.0 -4433.0
HARS2 -8183.0 -2570.0
HCFC1 1469.0 5667.0
HDAC1 -3835.0 3708.0
HDAC2 8973.0 3999.0
HDAC3 1719.0 6319.0
HDAC4 9329.0 9546.0
HDAC7 4750.0 7247.0
HDGF 7934.0 7771.0
HERC2 -10344.0 -6770.0
HERPUD1 8560.0 6924.0
HGS -381.0 6840.0
HIC1 -11023.0 -899.0
HIF1A 7330.0 7808.0
HIF3A -7283.0 927.0
HIPK2 -4431.0 8857.0
HLA-A -5067.0 570.0
HLA-B -1559.0 1570.0
HLTF -4927.0 -10182.0
HNRNPC 5157.0 7435.0
HNRNPK 7811.0 7654.0
HSP90B1 7042.0 372.0
HSPA5 8070.0 6713.0
HSPA8 -8286.0 -8908.0
HSPG2 -7219.0 -5674.0
HYOU1 -6582.0 2512.0
IARS1 -8945.0 -10625.0
IARS2 7584.0 5525.0
ICMT -3792.0 2455.0
IDE 8765.0 6765.0
IFIH1 -6483.0 -10093.0
IGFALS -9847.0 -6727.0
IGFBP2 9224.0 9782.0
IGFBP3 -8608.0 -8989.0
IGFBP4 -8033.0 -4877.0
IGFBP6 -5890.0 3738.0
IGFBP7 -5162.0 9129.0
IKBKE 387.0 6793.0
IKBKG -3058.0 7903.0
IL33 -438.0 931.0
INCENP -9437.0 323.0
ING2 5186.0 4738.0
INHBA 6428.0 2006.0
INO80 -9571.0 -1988.0
INO80B -9043.0 3286.0
INO80C 8592.0 5840.0
INO80D -4577.0 -3233.0
INO80E -8182.0 -4991.0
ITIH2 -9205.0 -3427.0
ITM2B 7772.0 5420.0
JOSD1 -8246.0 4503.0
JOSD2 4043.0 9627.0
KARS1 1343.0 -4436.0
KAT2A -6742.0 -10405.0
KAT2B 116.0 -1532.0
KBTBD6 -1477.0 2862.0
KBTBD7 3626.0 6975.0
KBTBD8 -1867.0 -3245.0
KCTD6 4870.0 5068.0
KCTD7 -9176.0 -10293.0
KDELR1 9552.0 9681.0
KDELR2 8771.0 7531.0
KDELR3 2255.0 -3318.0
KDM1B 6297.0 4922.0
KEAP1 -3358.0 7274.0
KHSRP 3052.0 4134.0
KIF13A 9932.0 10069.0
KIF5A -7037.0 -7903.0
KIF5B 9540.0 8103.0
KIF5C -2924.0 -10718.0
KIFC3 -10689.0 7291.0
KIN 3382.0 4220.0
KLF4 -1078.0 1442.0
KLHDC3 -1942.0 6306.0
KLHL11 -2734.0 -5716.0
KLHL2 9929.0 9615.0
KLHL20 -9314.0 -9256.0
KLHL21 663.0 6548.0
KLHL22 -10423.0 -8088.0
KLHL25 -9206.0 -9406.0
KLHL3 -8309.0 -11239.0
KLHL42 -4575.0 -7103.0
KLHL5 9255.0 2537.0
KLHL9 1973.0 2194.0
KLK1 -7316.0 -7453.0
KLK2 7104.0 1104.0
KTN1 7536.0 1922.0
L3MBTL2 -9641.0 -6612.0
LAMB1 2797.0 7716.0
LAMB2 3126.0 -317.0
LAMC1 9628.0 10118.0
LARGE1 -4555.0 -5687.0
LARGE2 2566.0 -5756.0
LARS1 8144.0 -9014.0
LARS2 -8769.0 -2878.0
LEO1 6728.0 -1045.0
LGALS1 8011.0 10042.0
LMAN1 -1255.0 -10522.0
LMAN2 2397.0 8522.0
LMAN2L 7675.0 6680.0
LMCD1 -8235.0 -8932.0
LMNA 1706.0 5027.0
LMO7 -3935.0 -10042.0
LONP2 -3890.0 -3747.0
LRR1 -7801.0 -3939.0
LRRC41 5384.0 8643.0
LSAMP 2156.0 1709.0
LTBP1 9092.0 8408.0
LTF 9374.0 3485.0
LY6E -10979.0 -10846.0
LYPD2 -11077.0 -6235.0
LYPD3 -6190.0 -6500.0
LYPD5 -6874.0 -3793.0
LYZ 9774.0 5791.0
MAGT1 574.0 3711.0
MAN1A1 4965.0 9297.0
MAN1A2 -1459.0 -993.0
MAN1B1 -7203.0 -495.0
MAN1C1 1436.0 -8761.0
MAN2A1 5542.0 -2948.0
MAN2A2 1864.0 8354.0
MANEA 6711.0 -5721.0
MAP3K7 1546.0 4274.0
MARCHF6 -3247.0 -1277.0
MARS1 -5741.0 1098.0
MARS2 -9047.0 -9576.0
MAT2B -6654.0 -7646.0
MAVS 6465.0 9067.0
MBD1 -1461.0 4147.0
MBD5 -3573.0 4398.0
MBD6 7308.0 8746.0
MBOAT4 -2505.0 -9193.0
MBTPS1 1704.0 4208.0
MBTPS2 2221.0 584.0
MCFD2 7963.0 7485.0
MCRS1 -9376.0 -1787.0
MDC1 -10561.0 -10461.0
MDGA1 -4452.0 -3553.0
MDM2 7204.0 3892.0
MDM4 4169.0 -2541.0
MELTF 2745.0 8465.0
MEN1 -8589.0 -4575.0
METTL21A 4851.0 4496.0
METTL22 -1028.0 7942.0
MFGE8 -535.0 4090.0
MGAT1 2229.0 8361.0
MGAT2 -5319.0 4067.0
MGAT3 2892.0 -5080.0
MGAT4A -3305.0 -4301.0
MGAT4B 9276.0 9187.0
MGAT4C 3599.0 -4032.0
MGAT5 -5440.0 -102.0
MIA2 6640.0 5566.0
MIA3 3397.0 -6425.0
MITF 9802.0 9484.0
MLEC 1226.0 3680.0
MME -1752.0 1424.0
MMP1 9240.0 6657.0
MOGS -5970.0 1434.0
MPDU1 7358.0 8337.0
MPI -6079.0 -9414.0
MRPL1 3175.0 -6887.0
MRPL10 -10121.0 -1505.0
MRPL11 -5974.0 125.0
MRPL12 1038.0 4117.0
MRPL13 5873.0 2381.0
MRPL14 -1506.0 -1353.0
MRPL15 2099.0 2057.0
MRPL16 2012.0 3234.0
MRPL17 -9033.0 -7459.0
MRPL18 5360.0 1663.0
MRPL19 6570.0 -1633.0
MRPL2 -8217.0 -2832.0
MRPL20 -208.0 1749.0
MRPL21 -1405.0 2519.0
MRPL22 887.0 2963.0
MRPL23 5233.0 8121.0
MRPL24 -5500.0 -3815.0
MRPL27 -3690.0 -156.0
MRPL28 1880.0 9161.0
MRPL3 2733.0 -230.0
MRPL30 7313.0 5306.0
MRPL32 -3191.0 -8101.0
MRPL33 7510.0 7515.0
MRPL34 -4997.0 2298.0
MRPL35 2383.0 -4337.0
MRPL36 -2598.0 4380.0
MRPL37 -1988.0 5181.0
MRPL38 -4941.0 -3834.0
MRPL39 -4161.0 -9581.0
MRPL4 -1925.0 -117.0
MRPL40 -8641.0 227.0
MRPL41 -1426.0 84.0
MRPL42 6309.0 -9825.0
MRPL43 -6701.0 1298.0
MRPL44 5420.0 5142.0
MRPL45 7197.0 1331.0
MRPL46 -3390.0 -7627.0
MRPL47 6626.0 3338.0
MRPL48 3529.0 -3329.0
MRPL49 -9785.0 -3850.0
MRPL50 2110.0 -9508.0
MRPL51 1812.0 6253.0
MRPL52 2573.0 4992.0
MRPL53 594.0 7564.0
MRPL54 -5806.0 1715.0
MRPL55 -7828.0 -2019.0
MRPL57 -1571.0 596.0
MRPL58 5600.0 4186.0
MRPL9 -10010.0 -6273.0
MRPS10 8207.0 3624.0
MRPS11 -4396.0 4586.0
MRPS12 -6744.0 839.0
MRPS14 2359.0 -5168.0
MRPS15 -2496.0 3891.0
MRPS16 4015.0 5274.0
MRPS17 -206.0 -5302.0
MRPS18A -2110.0 2708.0
MRPS18B -8080.0 -7607.0
MRPS18C 1575.0 1282.0
MRPS2 -5942.0 -3499.0
MRPS21 -8716.0 -5244.0
MRPS22 5190.0 1467.0
MRPS23 2552.0 2605.0
MRPS24 -1884.0 4564.0
MRPS25 -1296.0 -10530.0
MRPS26 -7761.0 -2101.0
MRPS27 -1262.0 -7779.0
MRPS28 3816.0 1261.0
MRPS30 -94.0 -6935.0
MRPS31 -1141.0 -3315.0
MRPS33 -3512.0 -8728.0
MRPS34 103.0 5384.0
MRPS35 6911.0 1635.0
MRPS36 8406.0 6931.0
MRPS5 5371.0 5756.0
MRPS6 -8797.0 -9055.0
MRPS7 3421.0 3484.0
MRPS9 -8990.0 -8936.0
MRRF -3559.0 -8215.0
MRTFA 7793.0 9266.0
MSLN -8481.0 3943.0
MSRA 4144.0 8166.0
MSRB1 9735.0 9746.0
MSRB2 9375.0 9544.0
MSRB3 8439.0 6436.0
MT-RNR1 -1023.0 1206.0
MT-RNR2 -373.0 3642.0
MT-TV -9270.0 940.0
MTA1 -550.0 -1521.0
MTFMT -772.0 4767.0
MTIF2 5695.0 -1438.0
MTIF3 5805.0 2380.0
MTRF1L 7068.0 4745.0
MUC1 8159.0 7011.0
MUC12 -8506.0 -9690.0
MUC16 377.0 -5584.0
MUC20 -2625.0 -6328.0
MUC4 643.0 -4710.0
MUC5B -8416.0 -622.0
MUC6 -3460.0 -1745.0
MUCL1 -1878.0 -1414.0
MUL1 -4019.0 5276.0
MVD -10176.0 2670.0
MXRA8 -5732.0 -6638.0
MYC 8429.0 -2186.0
MYDGF 5166.0 8583.0
MYO5A 6789.0 7727.0
MYSM1 -2988.0 -7508.0
N6AMT1 -6371.0 -10827.0
NAE1 -6037.0 -10474.0
NAGK 6329.0 2553.0
NANP -8562.0 -6438.0
NANS 8296.0 8165.0
NAPA -2447.0 3305.0
NAPB -291.0 -2004.0
NAPG 7409.0 3591.0
NAPSA -5395.0 -1785.0
NARS1 9107.0 3543.0
NARS2 -134.0 -9409.0
NAT8B -8358.0 693.0
NCOA1 -1753.0 6268.0
NCOA2 -4443.0 3788.0
NCOR2 4843.0 9646.0
NCSTN 9503.0 9869.0
NDC1 -9151.0 -11223.0
NEDD8 -156.0 8587.0
NEGR1 1134.0 2142.0
NEU1 9336.0 9571.0
NEU3 -1390.0 -1896.0
NEURL2 -6006.0 -329.0
NFKB2 3069.0 -1167.0
NFKBIA 6855.0 7374.0
NFRKB -4887.0 950.0
NFYA 3506.0 4239.0
NFYB -726.0 -10664.0
NFYC 6238.0 8722.0
NGLY1 -86.0 -2388.0
NICN1 -5684.0 1539.0
NLRP3 9708.0 8944.0
NOD1 -10930.0 -10348.0
NOD2 9408.0 8613.0
NOP56 -8057.0 -10682.0
NOP58 3298.0 -10545.0
NPL 10063.0 10123.0
NPM1 306.0 -10502.0
NPPA -3401.0 1108.0
NR1H2 4003.0 8448.0
NR1H3 -8939.0 2196.0
NR2C1 -5368.0 -9461.0
NR3C1 -5002.0 2698.0
NR3C2 -6020.0 -10768.0
NR4A2 -4347.0 3.0
NRIP1 4155.0 5430.0
NRN1 8397.0 9179.0
NRN1L -7189.0 -5742.0
NSF 8895.0 9680.0
NSMCE1 4738.0 7075.0
NSMCE2 5069.0 6823.0
NSMCE3 -10366.0 -8394.0
NSMCE4A -9103.0 -9613.0
NTNG2 -2845.0 6248.0
NUB1 -10205.0 -10007.0
NUCB1 8538.0 9717.0
NUDT14 -3679.0 -4528.0
NUP107 -4463.0 -10317.0
NUP133 -4339.0 -4616.0
NUP153 -7195.0 -2408.0
NUP155 -4644.0 -9292.0
NUP160 -2518.0 -10020.0
NUP188 -9467.0 -9810.0
NUP205 -8533.0 -9667.0
NUP210 -10480.0 -5943.0
NUP214 8588.0 8152.0
NUP35 -4281.0 -10256.0
NUP37 3188.0 3613.0
NUP42 1567.0 -5400.0
NUP43 -55.0 -10161.0
NUP50 6614.0 4617.0
NUP54 2794.0 -9194.0
NUP58 9637.0 9212.0
NUP62 3053.0 1921.0
NUP85 1119.0 -2732.0
NUP88 -7116.0 -10078.0
NUP93 -9095.0 -8944.0
NUP98 208.0 4310.0
NUS1 9194.0 7298.0
OBSL1 -10027.0 2453.0
OGT -3036.0 -7273.0
OS9 8889.0 9708.0
OTUB1 -5323.0 4596.0
OTUB2 44.0 -533.0
OTUD3 -6891.0 -9799.0
OTUD5 -9093.0 2293.0
OTUD7A -10002.0 -9866.0
OTUD7B -11017.0 -9453.0
OTULIN 3200.0 -288.0
OXA1L 8084.0 4963.0
P2RY2 6847.0 6014.0
P4HB 6474.0 9641.0
PABPC1 8362.0 4524.0
PAF1 -5217.0 5851.0
PAPPA 1497.0 -5053.0
PARK7 4896.0 7394.0
PARN -1817.0 -1800.0
PARP1 -10438.0 -8545.0
PARS2 -7381.0 -2505.0
PCGF2 -3955.0 -2094.0
PCMT1 9643.0 8873.0
PCNA 613.0 -5415.0
PDCL 30.0 363.0
PDIA3 2037.0 4838.0
PDIA5 8861.0 7320.0
PDIA6 7671.0 5364.0
PEX10 -9614.0 1012.0
PEX12 -6667.0 -7170.0
PEX13 4317.0 285.0
PEX14 -9676.0 6797.0
PEX2 287.0 4591.0
PEX5 -1877.0 5897.0
PFDN1 -3048.0 5708.0
PFDN2 -2364.0 3655.0
PFDN4 5450.0 -294.0
PFDN5 1751.0 4700.0
PFDN6 -6156.0 2506.0
PGA3 8937.0 6702.0
PGA4 7635.0 7133.0
PGA5 7621.0 8062.0
PGAP1 7057.0 -10862.0
PGM3 7906.0 -5172.0
PHC1 -5034.0 -8115.0
PHC2 8426.0 9918.0
PHC3 -3083.0 -7777.0
PIAS1 9212.0 7268.0
PIAS2 -2649.0 -6975.0
PIAS3 -3766.0 1150.0
PIAS4 -1432.0 8309.0
PIGA -995.0 -6961.0
PIGB 2518.0 4698.0
PIGC 1841.0 -303.0
PIGF 8088.0 7114.0
PIGG -6117.0 -6858.0
PIGH -8202.0 -6648.0
PIGK -4713.0 -3776.0
PIGL -9453.0 -10803.0
PIGM 4550.0 -642.0
PIGN 3457.0 3051.0
PIGO -9860.0 -3302.0
PIGP 2426.0 -5745.0
PIGQ -2492.0 4360.0
PIGS 1889.0 8350.0
PIGT -5131.0 3913.0
PIGU -227.0 -8489.0
PIGV -7824.0 3121.0
PIGW -9044.0 -10468.0
PIGX 8092.0 4615.0
PIGZ -2842.0 5053.0
PLA2G4B -1937.0 -7077.0
PLA2G7 1500.0 -7694.0
PLAUR 8428.0 9009.0
PLG 1277.0 -2998.0
PML -6449.0 -6720.0
PMM1 -3254.0 6102.0
PMM2 7431.0 -439.0
PNPLA2 9239.0 9613.0
POFUT2 -8902.0 -9091.0
POLB 410.0 -7278.0
POM121 -8969.0 -3230.0
POM121C -9525.0 -1010.0
POMC 1489.0 3391.0
POMGNT1 -10525.0 -9638.0
POMGNT2 -8918.0 2070.0
POMK -4122.0 302.0
POMT1 -3743.0 -8982.0
POMT2 -619.0 2396.0
PPA1 7407.0 -715.0
PPA2 3091.0 2489.0
PPARA -791.0 2682.0
PPARG 10111.0 10137.0
PPARGC1A 7923.0 1692.0
PPP2R5B 5288.0 7952.0
PPP6C 8559.0 6316.0
PPP6R1 -5320.0 7658.0
PPP6R3 3008.0 3925.0
PREB -1638.0 8142.0
PRKCSH -3697.0 7582.0
PRKDC -8444.0 -7899.0
PRMT3 7417.0 -1287.0
PROC -10857.0 -3490.0
PROS1 9065.0 7937.0
PROZ 174.0 -4404.0
PRSS21 759.0 -836.0
PRSS23 -11252.0 -8805.0
PSENEN 2692.0 7551.0
PSMA1 8278.0 7406.0
PSMA2 5830.0 5666.0
PSMA3 4646.0 -7621.0
PSMA4 3950.0 -1036.0
PSMA5 -2119.0 -3983.0
PSMA6 6893.0 5865.0
PSMA7 3550.0 8554.0
PSMB1 3915.0 4224.0
PSMB10 -7878.0 -1272.0
PSMB2 2664.0 4928.0
PSMB3 4971.0 8382.0
PSMB4 -3175.0 4911.0
PSMB5 6561.0 9138.0
PSMB6 1312.0 8784.0
PSMB7 8034.0 9051.0
PSMB8 -4481.0 75.0
PSMB9 -9105.0 -10433.0
PSMC1 6759.0 7782.0
PSMC2 -2524.0 4517.0
PSMC3 -4971.0 4984.0
PSMC4 -10757.0 -336.0
PSMC5 -3424.0 2764.0
PSMC6 8812.0 6000.0
PSMD1 7679.0 7587.0
PSMD10 2067.0 2450.0
PSMD11 6914.0 6824.0
PSMD12 9011.0 5710.0
PSMD13 3157.0 7205.0
PSMD14 2891.0 3041.0
PSMD2 4352.0 8396.0
PSMD3 -2243.0 6367.0
PSMD4 6858.0 9449.0
PSMD5 2770.0 4781.0
PSMD6 8841.0 8304.0
PSMD7 6534.0 6147.0
PSMD8 739.0 7117.0
PSMD9 3580.0 9001.0
PSME1 -7256.0 -7913.0
PSME2 -5548.0 -10355.0
PSME3 9120.0 8239.0
PSME4 -5205.0 -3127.0
PSMF1 6709.0 6770.0
PTCD3 -6656.0 -8529.0
PTEN 9191.0 8752.0
PTP4A2 714.0 3952.0
PTRH2 9404.0 1694.0
PUM2 2582.0 -1706.0
QARS1 -4041.0 2620.0
QSOX1 9451.0 10048.0
RAB10 9303.0 9477.0
RAB11A 9786.0 8252.0
RAB11B -3172.0 6936.0
RAB12 5316.0 -2681.0
RAB13 10014.0 10088.0
RAB14 8215.0 7014.0
RAB15 -6713.0 -3173.0
RAB18 9425.0 7287.0
RAB19 -4588.0 4873.0
RAB1A 9700.0 9407.0
RAB1B 5676.0 9455.0
RAB20 8490.0 9234.0
RAB21 7222.0 6309.0
RAB22A -3504.0 -1333.0
RAB23 4069.0 39.0
RAB24 2905.0 6201.0
RAB26 2250.0 -7181.0
RAB27A 9164.0 8675.0
RAB27B -847.0 4689.0
RAB29 -10737.0 -4912.0
RAB2A 9085.0 9113.0
RAB2B -5115.0 -7189.0
RAB30 -7367.0 -8558.0
RAB31 9956.0 9895.0
RAB32 10006.0 10036.0
RAB33A -10854.0 -5029.0
RAB33B 8756.0 6897.0
RAB34 8570.0 9028.0
RAB35 -6982.0 6352.0
RAB36 651.0 6588.0
RAB37 -11095.0 -6455.0
RAB38 -10061.0 -3007.0
RAB39A 8587.0 6613.0
RAB39B -9791.0 -9905.0
RAB3A 7816.0 8757.0
RAB3B -3348.0 -1420.0
RAB3D 9596.0 9946.0
RAB40B -8198.0 -11061.0
RAB40C 6619.0 9309.0
RAB41 -20.0 -4213.0
RAB42 -2106.0 5881.0
RAB43 4478.0 7506.0
RAB44 4572.0 -693.0
RAB4A 9473.0 7027.0
RAB4B -7808.0 7089.0
RAB5A 8478.0 6815.0
RAB5B 3295.0 7820.0
RAB5C 7846.0 9422.0
RAB6A 8487.0 8616.0
RAB6B 6925.0 6712.0
RAB7A 8897.0 9367.0
RAB7B -7654.0 2220.0
RAB8A 540.0 5295.0
RAB8B 6227.0 7055.0
RAB9A 2889.0 5200.0
RAB9B -5682.0 -4620.0
RABGGTA -5925.0 1157.0
RABGGTB 5217.0 -8376.0
RAD18 -9629.0 -11080.0
RAD21 3724.0 1987.0
RAD23A 7262.0 6302.0
RAD23B 9180.0 9565.0
RAD52 3180.0 -1444.0
RAE1 4777.0 6291.0
RANBP2 4453.0 -2222.0
RANGAP1 -10259.0 -9220.0
RARA -356.0 8119.0
RARS1 1042.0 -3848.0
RARS2 4034.0 -713.0
RBBP5 4931.0 173.0
RBBP7 -10846.0 -9848.0
RBX1 1418.0 4877.0
RCE1 -3787.0 -2010.0
RCN1 -7373.0 -9138.0
RECK 146.0 -9535.0
RELA -7305.0 2739.0
RENBP 6011.0 7767.0
RFT1 7279.0 3586.0
RGS6 6835.0 6389.0
RGS9 -10609.0 -4448.0
RHOA 8351.0 8888.0
RHOT1 10010.0 9811.0
RING1 -6720.0 548.0
RIPK1 -10879.0 -4699.0
RIPK2 1665.0 2297.0
RNF103 -5944.0 2.0
RNF123 3943.0 8163.0
RNF135 8493.0 9341.0
RNF139 1735.0 3515.0
RNF144A -8522.0 -10220.0
RNF146 8442.0 9760.0
RNF152 5182.0 2967.0
RNF168 -8794.0 648.0
RNF181 3911.0 7149.0
RNF185 3476.0 7488.0
RNF2 5589.0 3400.0
RNF20 5931.0 6804.0
RNF40 363.0 8641.0
RNF5 -8439.0 -1294.0
RNF7 6703.0 8617.0
RORA -10511.0 -10952.0
RPA1 -10457.0 -9792.0
RPL10 -5353.0 -4722.0
RPL10A -1883.0 -6533.0
RPL11 -1931.0 -5590.0
RPL12 -4453.0 -5830.0
RPL13 -1749.0 -2925.0
RPL13A -5236.0 -7060.0
RPL14 -3538.0 -6408.0
RPL15 2144.0 -270.0
RPL17 -2803.0 -4216.0
RPL18 -2407.0 -4107.0
RPL18A -4338.0 -4740.0
RPL19 -5605.0 -4047.0
RPL21 -2408.0 -6412.0
RPL22 1616.0 -5576.0
RPL22L1 3994.0 -3396.0
RPL23 -353.0 -2321.0
RPL23A -4695.0 -9373.0
RPL24 -3568.0 -4504.0
RPL26 -4494.0 -4767.0
RPL26L1 6548.0 7865.0
RPL27 -3684.0 -361.0
RPL27A -5814.0 -4093.0
RPL28 -2567.0 614.0
RPL29 -2138.0 -1913.0
RPL3 -6886.0 -7461.0
RPL30 -5225.0 -5596.0
RPL31 -2656.0 -3267.0
RPL32 -3094.0 -6607.0
RPL34 -2097.0 -7114.0
RPL35 -8453.0 -5007.0
RPL35A -2671.0 -5323.0
RPL36 -6761.0 -2662.0
RPL36A -5740.0 -5975.0
RPL36AL -1773.0 1920.0
RPL37 -8529.0 -2184.0
RPL37A -5802.0 -727.0
RPL38 -7075.0 -2793.0
RPL39 -983.0 -3231.0
RPL39L -10310.0 -4203.0
RPL4 2174.0 -3722.0
RPL41 -7404.0 -3692.0
RPL5 2979.0 -5487.0
RPL6 3510.0 -3949.0
RPL7 3811.0 -2799.0
RPL7A -2851.0 -1500.0
RPL8 -4534.0 1780.0
RPL9 -167.0 -2256.0
RPLP0 3127.0 -1531.0
RPLP1 -2483.0 2491.0
RPLP2 -7230.0 -4974.0
RPN1 7629.0 8737.0
RPN2 5890.0 7636.0
RPS10 -5228.0 -3784.0
RPS11 -7652.0 -3921.0
RPS12 -4698.0 -5458.0
RPS13 3315.0 -2060.0
RPS14 -6862.0 -2786.0
RPS15 -4712.0 -988.0
RPS15A -3464.0 -4486.0
RPS16 -3811.0 -3249.0
RPS17 -6899.0 -3309.0
RPS18 -6859.0 -6415.0
RPS19 -5797.0 -5539.0
RPS2 -6072.0 -1316.0
RPS20 -6536.0 -7674.0
RPS21 -4436.0 -2455.0
RPS23 -1921.0 -5872.0
RPS24 3926.0 -838.0
RPS25 -1359.0 -6741.0
RPS26 -1177.0 -1112.0
RPS27 -9041.0 -7909.0
RPS27A -3555.0 -7070.0
RPS27L 5307.0 1458.0
RPS28 -5391.0 -2679.0
RPS29 -8497.0 -5396.0
RPS3 -4098.0 -4595.0
RPS3A 3428.0 -6271.0
RPS4X -1869.0 -6447.0
RPS4Y1 5773.0 -56.0
RPS5 -4290.0 -4473.0
RPS6 -1613.0 -5951.0
RPS7 -1789.0 -4131.0
RPS8 2338.0 -2478.0
RPS9 3357.0 6145.0
RPSA -2286.0 -5572.0
RRAGA -920.0 7747.0
RTF1 1518.0 4233.0
RTN4RL1 5909.0 -639.0
RTN4RL2 4129.0 8407.0
RUVBL1 -5940.0 -5741.0
RWDD3 5206.0 -1627.0
RXRA 6327.0 8932.0
SAE1 -9557.0 -1648.0
SAFB 638.0 4869.0
SAR1B 8795.0 5984.0
SARS1 -7170.0 -134.0
SARS2 -10197.0 -7574.0
SATB1 -455.0 -8786.0
SATB2 8345.0 6299.0
SBSPON -553.0 -8704.0
SCFD1 4551.0 3924.0
SCMH1 2787.0 -7207.0
SDC2 7232.0 4710.0
SEC11A 8033.0 8529.0
SEC11C -1541.0 -8468.0
SEC13 2125.0 6861.0
SEC16A -2929.0 6748.0
SEC16B -1454.0 1213.0
SEC22A 374.0 -4424.0
SEC22B 8663.0 4943.0
SEC22C -2377.0 -1611.0
SEC23A 8776.0 6905.0
SEC23IP 5231.0 -574.0
SEC24A 8318.0 7788.0
SEC24B 1663.0 5398.0
SEC24C -9662.0 3561.0
SEC24D 8017.0 8795.0
SEC31A 1743.0 2474.0
SEC61A1 5496.0 7020.0
SEC61A2 -8826.0 -9671.0
SEC61B 4953.0 8362.0
SEC61G 7533.0 3614.0
SEH1L 7189.0 -8511.0
SEL1L 7157.0 7252.0
SELENOS -4119.0 1116.0
SEM1 993.0 5942.0
SEMA5A -7754.0 -9477.0
SEMA5B -1476.0 3843.0
SENP1 -8006.0 -3664.0
SENP2 5008.0 4389.0
SENP5 -824.0 -5825.0
SENP8 7374.0 893.0
SERP1 8966.0 8960.0
SERPINA1 9571.0 9817.0
SERPINA10 4955.0 3958.0
SERPIND1 -5478.0 -489.0
SFTPB 4839.0 633.0
SFTPD -11105.0 -7143.0
SHC1 -3416.0 5815.0
SHISA5 -7800.0 3831.0
SHPRH -4011.0 -8036.0
SIAH1 -5833.0 454.0
SIAH2 9783.0 8092.0
SIN3A -9037.0 -7770.0
SKIV2L -7829.0 2289.0
SKP1 8120.0 2700.0
SKP2 -2615.0 -7161.0
SLC17A5 3558.0 5793.0
SLC30A5 4019.0 -2234.0
SLC30A6 3288.0 356.0
SLC30A7 2244.0 -5266.0
SLC34A1 -6058.0 865.0
SLC34A2 6195.0 -1412.0
SLC35A1 9102.0 6415.0
SLC35C1 1561.0 3694.0
SMAD1 7656.0 9731.0
SMAD2 5238.0 5871.0
SMAD3 -10084.0 -10081.0
SMAD4 -3009.0 -6696.0
SMAD7 -11234.0 -5230.0
SMC1A -2815.0 3295.0
SMC3 6086.0 -4018.0
SMC5 3643.0 -9046.0
SMC6 729.0 -4517.0
SMURF2 -9128.0 -7045.0
SNCA 10059.0 9505.0
SNX3 9914.0 9837.0
SOCS2 4901.0 -4080.0
SOCS3 9830.0 10110.0
SOCS5 6009.0 2808.0
SOCS6 8906.0 9207.0
SORL1 2295.0 7377.0
SP100 5494.0 4353.0
SP3 7059.0 5694.0
SPCS1 2056.0 4128.0
SPCS2 5751.0 2672.0
SPCS3 7915.0 3192.0
SPHK1 8030.0 8271.0
SPON1 -5400.0 -9627.0
SPON2 -11244.0 -8318.0
SPRN -7133.0 -9252.0
SPSB1 -2844.0 4000.0
SPSB2 -9283.0 1413.0
SPSB3 -8986.0 -388.0
SPTA1 9470.0 6216.0
SPTAN1 -10174.0 -8889.0
SPTB 9958.0 9302.0
SPTBN1 -6572.0 -6164.0
SPTBN2 -5447.0 -3871.0
SPTBN5 -7557.0 -461.0
SRD5A3 3417.0 4347.0
SRP14 4915.0 7324.0
SRP19 7471.0 3529.0
SRP54 8621.0 6071.0
SRP68 2507.0 3406.0
SRP72 3037.0 -1290.0
SRP9 7258.0 3646.0
SRPRA -2427.0 6646.0
SRPRB -4484.0 -7853.0
SSR1 8551.0 6078.0
SSR2 1479.0 3995.0
SSR3 7595.0 5737.0
SSR4 -490.0 4890.0
ST3GAL1 -6884.0 -3859.0
ST3GAL2 7832.0 9657.0
ST3GAL3 2775.0 828.0
ST3GAL4 -9921.0 7993.0
ST3GAL5 -8483.0 -10211.0
ST3GAL6 9317.0 5155.0
ST6GAL1 -10673.0 -10107.0
ST6GAL2 -6498.0 1859.0
ST6GALNAC1 1128.0 -7500.0
ST6GALNAC2 6233.0 7200.0
ST6GALNAC3 8893.0 9823.0
ST6GALNAC4 -4762.0 1735.0
ST6GALNAC6 -10863.0 -9916.0
ST8SIA1 160.0 -9368.0
ST8SIA4 9016.0 8665.0
ST8SIA5 317.0 2482.0
ST8SIA6 -10982.0 -6606.0
STAG1 -6902.0 -2525.0
STAG2 7287.0 5015.0
STAM 3046.0 2017.0
STAM2 8115.0 5912.0
STAMBP -1020.0 4263.0
STAMBPL1 -5729.0 -9607.0
STAT3 8512.0 8606.0
STS 1348.0 5281.0
STT3A 3820.0 5008.0
STX17 -4480.0 -10772.0
STX1A -9454.0 1322.0
STX5 3566.0 8258.0
SUDS3 6591.0 4895.0
SULT1A3 4142.0 4659.0
SUMF1 9162.0 9651.0
SUMF2 -10998.0 -8612.0
SUMO1 7968.0 6798.0
SUMO2 6089.0 5153.0
SUMO3 6805.0 7483.0
SUZ12 4539.0 -3535.0
SYVN1 734.0 2029.0
TAB1 6623.0 5746.0
TADA2B 4725.0 7618.0
TADA3 -1163.0 9039.0
TAF10 2322.0 8682.0
TAF9B 6761.0 -6403.0
TARS1 4791.0 3011.0
TARS2 -10229.0 -8135.0
TATDN2 -9899.0 -3340.0
TBC1D20 -6556.0 3818.0
TBCA 5661.0 5870.0
TBCB -7971.0 6771.0
TBCC -10293.0 -4108.0
TBCD -9289.0 -5231.0
TBCE -3383.0 256.0
TCF7L2 -10402.0 -1302.0
TCP1 7677.0 2853.0
TDG 8035.0 6656.0
TECTA -8588.0 -1298.0
TF 1794.0 1244.0
TFG 8930.0 6725.0
TFPT 1573.0 7442.0
TGFA 7935.0 9686.0
TGFB1 -2566.0 6745.0
TGFBI 9472.0 7853.0
TGFBR1 -7960.0 3224.0
TGFBR2 -5037.0 6173.0
TGOLN2 8606.0 9683.0
THBS1 1778.0 8102.0
THRA -9647.0 -866.0
THRB -1682.0 3605.0
THSD1 -3671.0 -6837.0
THSD4 -4394.0 -1859.0
THSD7A -6799.0 -6728.0
TIMP1 6136.0 9944.0
TLN1 7865.0 9661.0
TMED10 35.0 2168.0
TMED2 6426.0 6360.0
TMED3 -2098.0 4751.0
TMED7 9038.0 7918.0
TMED9 917.0 9007.0
TMEM115 31.0 6881.0
TMEM129 345.0 5404.0
TMEM132A 6765.0 4841.0
TNC -1334.0 -4015.0
TNFAIP3 -10682.0 -6292.0
TNIP1 6944.0 9401.0
TNIP2 -1490.0 7359.0
TNIP3 -8226.0 -6253.0
TNKS -7769.0 -6024.0
TNKS2 604.0 1179.0
TOMM20 6504.0 -4519.0
TOMM70 -2701.0 -7580.0
TOP1 9095.0 7736.0
TOP2A 2516.0 2007.0
TOP2B 1474.0 -1831.0
TOPORS 4682.0 2877.0
TP53 -7284.0 -8934.0
TP53BP1 -7310.0 -9882.0
TPGS1 -2382.0 6645.0
TPGS2 -4317.0 -763.0
TPP1 9439.0 9395.0
TPR -1066.0 -7983.0
TPST1 9124.0 9903.0
TPST2 -8995.0 8264.0
TRAF2 -9898.0 -9879.0
TRAF3 2694.0 -5265.0
TRAF6 -1767.0 2089.0
TRAM1 1953.0 -3908.0
TRAPPC1 5277.0 9110.0
TRAPPC10 -10478.0 -2812.0
TRAPPC2 -8890.0 -5344.0
TRAPPC2L -350.0 -932.0
TRAPPC3 6827.0 7922.0
TRAPPC4 -7161.0 -2663.0
TRAPPC5 4081.0 6280.0
TRAPPC6A -7665.0 -10218.0
TRAPPC6B 6230.0 4019.0
TRAPPC9 921.0 7473.0
TRIM13 -969.0 -1503.0
TRIM25 8976.0 8487.0
TRIM27 9047.0 8593.0
TRIM28 -4783.0 -1562.0
TRMT112 -4210.0 3619.0
TRRAP -7730.0 -2671.0
TSFM 3808.0 1942.0
TSPAN14 -706.0 8468.0
TSPAN15 483.0 -2580.0
TSPAN33 7193.0 6475.0
TSPAN5 2115.0 971.0
TSPYL2 -7470.0 -10801.0
TSTA3 6432.0 6332.0
TTF1 4199.0 -954.0
TTL 1207.0 -3562.0
TTLL1 -6316.0 -4940.0
TTLL11 -4397.0 -2844.0
TTLL12 2186.0 6431.0
TTLL13P -10308.0 -2008.0
TTLL3 -6915.0 1425.0
TTLL4 9103.0 7623.0
TTLL5 -7569.0 481.0
TTLL7 8840.0 5402.0
TUBA1A 6178.0 7845.0
TUBA1B 1572.0 6394.0
TUBA1C 7082.0 7744.0
TUBA3D -4511.0 -9736.0
TUBA4A 652.0 7677.0
TUBA4B -4789.0 3660.0
TUBA8 8044.0 7112.0
TUBB1 6239.0 6225.0
TUBB2A 8108.0 9349.0
TUBB3 -1306.0 3835.0
TUBB4A -6145.0 -8199.0
TUBB4B 6246.0 7789.0
TUBB6 1680.0 7491.0
TUFM 738.0 6006.0
TULP4 -4979.0 -1281.0
TXN 8317.0 8729.0
UAP1 -10828.0 -9681.0
UBA1 2505.0 8454.0
UBA2 1891.0 -5813.0
UBA3 9502.0 7030.0
UBA52 -1875.0 3023.0
UBA6 4933.0 3279.0
UBB 8251.0 6157.0
UBC -1915.0 5825.0
UBE2A 7726.0 8032.0
UBE2B 8648.0 6410.0
UBE2C 3717.0 5687.0
UBE2D1 9825.0 9491.0
UBE2D2 2673.0 5593.0
UBE2D3 9443.0 8783.0
UBE2E1 8528.0 6289.0
UBE2E3 5727.0 5064.0
UBE2F 960.0 8586.0
UBE2G1 3646.0 5958.0
UBE2G2 719.0 -9159.0
UBE2H 7660.0 8041.0
UBE2I -4201.0 2754.0
UBE2J2 7098.0 9468.0
UBE2K 8831.0 6196.0
UBE2L3 7416.0 7794.0
UBE2L6 -8809.0 -9855.0
UBE2M 2776.0 9251.0
UBE2N 4087.0 2050.0
UBE2Q2 -8213.0 -9964.0
UBE2R2 8380.0 9338.0
UBE2S 3693.0 5680.0
UBE2T -2666.0 -8388.0
UBE2V2 6427.0 1996.0
UBE2W 9632.0 7147.0
UBE2Z -9598.0 -6520.0
UBXN1 -7382.0 5180.0
UBXN7 2090.0 2374.0
UCHL3 6245.0 65.0
UCHL5 -1550.0 -6617.0
UCN -3909.0 -2780.0
UGGT1 2808.0 6596.0
UGGT2 7847.0 4069.0
UHRF2 -3722.0 -9636.0
UIMC1 9820.0 9822.0
USO1 6916.0 3905.0
USP10 8963.0 7208.0
USP11 -11165.0 -10441.0
USP12 8366.0 3679.0
USP13 -4013.0 -5427.0
USP14 -4406.0 -2591.0
USP15 8878.0 4964.0
USP16 1399.0 -8582.0
USP18 -10888.0 -10755.0
USP19 -8276.0 4372.0
USP20 -9609.0 -9844.0
USP21 -4240.0 -4963.0
USP22 5113.0 8715.0
USP24 -10050.0 -8289.0
USP25 5730.0 -1016.0
USP28 -11213.0 -9807.0
USP3 9151.0 9670.0
USP30 -296.0 2849.0
USP33 5005.0 -1397.0
USP34 -268.0 385.0
USP37 -7125.0 -9304.0
USP4 7420.0 8819.0
USP42 -10240.0 -7493.0
USP44 -2233.0 -7057.0
USP47 -3965.0 -1174.0
USP48 8881.0 3072.0
USP49 3927.0 2920.0
USP5 -7696.0 -412.0
USP7 5480.0 7173.0
USP8 8542.0 6497.0
USP9X 4318.0 6232.0
VAMP2 -9677.0 -10779.0
VARS1 -6690.0 -2776.0
VARS2 -2964.0 -4784.0
VBP1 8653.0 3493.0
VCAN 10068.0 10125.0
VCP 3600.0 7754.0
VCPIP1 -736.0 1057.0
VCPKMT 1560.0 696.0
VDAC1 6643.0 4063.0
VDAC2 8674.0 7660.0
VDAC3 463.0 1981.0
VDR 7908.0 9387.0
VHL -212.0 6007.0
VNN1 9174.0 9668.0
VNN2 9583.0 9574.0
VNN3 5862.0 5923.0
WAC 380.0 7136.0
WARS1 -2995.0 -8082.0
WARS2 5383.0 -6229.0
WDR20 -5900.0 2686.0
WDR48 -7124.0 -9778.0
WDR5 671.0 2111.0
WDR61 4426.0 -254.0
WDTC1 -5027.0 8434.0
WFS1 -9892.0 -5570.0
WIPI1 4798.0 7847.0
WRAP53 -9279.0 -4651.0
WRN -8612.0 -11220.0
WSB1 8808.0 8048.0
WSB2 7454.0 8057.0
XBP1 -4949.0 1223.0
XPC -9936.0 -8260.0
XPNPEP2 -11086.0 -9756.0
XRCC4 7049.0 7016.0
XRN2 9895.0 9902.0
YARS1 -8870.0 781.0
YARS2 3217.0 -2856.0
YIF1A -2326.0 2448.0
YKT6 -3724.0 6818.0
YOD1 8515.0 7196.0
YY1 -627.0 3060.0
ZBED1 -403.0 8068.0
ZBTB16 -9729.0 5951.0
ZBTB17 -8793.0 6169.0
ZDHHC2 7463.0 4572.0
ZNF131 -5951.0 -9975.0
ZNF350 -5482.0 -95.0
ZRANB1 4893.0 3821.0



Post-translational protein modification

Post-translational protein modification
metric value
setSize 1183
pMANOVA 2.92e-28
p.adjustMANOVA 4.42e-26
s.dist 0.215
s.low.CRP 0.0971
s.high.CRP 0.192
p.low.CRP 1.84e-08
p.high.CRP 7e-29




Top 20 genes
Gene low CRP high CRP
ADAMTS2 10123 10126
PPARG 10111 10137
FAM20A 10078 10142
CTSA 10083 10131
VCAN 10068 10125
NPL 10063 10123
F5 10084 10070
ASGR2 10000 10129
RAB13 10014 10088
BST1 10108 9972
FBXO9 10081 9997
RAB32 10006 10036
SOCS3 9830 10110
RAB31 9956 9895
RHOT1 10010 9811
FAM20C 9723 10066
CKAP4 10101 9674
FBXL5 10052 9713
SNX3 9914 9837
LAMC1 9628 10118

Click HERE to show all gene set members

All member genes
low CRP high CRP
AAAS -8564 -4273
ACTB 9310 9714
ACTL6A -1737 -5002
ACTR10 8589 7569
ACTR1A -2833 8680
ACTR5 -9698 -8731
ACTR8 -8619 1129
ADAM10 9314 9481
ADAMTS1 -11098 -5754
ADAMTS10 -10752 -8150
ADAMTS13 -3300 -3397
ADAMTS14 -10382 -1142
ADAMTS16 -5113 -7987
ADAMTS17 1930 -5706
ADAMTS2 10123 10126
ADAMTS4 -10045 -8251
ADAMTS5 4721 -5392
ADAMTS6 -6097 -5389
ADAMTSL3 2431 443
ADAMTSL4 7713 8020
ADAMTSL5 462 -10240
ADRB2 -11122 -7027
ADRM1 -4693 6271
AGBL2 -6515 -8090
AGBL3 -3436 -9749
AGBL5 6194 3218
AGTPBP1 8935 8653
ALB 1254 3551
ALG1 -9753 -1781
ALG10 -6726 -6482
ALG10B 1984 -9722
ALG11 -3019 -1403
ALG12 -787 4333
ALG13 -1043 -8422
ALG14 7527 5733
ALG2 3111 -119
ALG3 2590 -813
ALG5 4020 -1165
ALG6 5735 527
ALG8 4756 -5192
ALG9 -6685 -8829
ALPL 8116 9417
AMDHD2 -10278 -6693
AMFR 8281 7316
ANK1 9797 8626
ANK3 3262 -7407
ANKRD28 -5795 -3898
ANKRD9 8481 8619
ANO8 6301 6525
APC 3083 3959
APLP2 9601 10056
APOA2 2715 7325
APOE -5022 1771
APOL1 -7427 -4732
APP 9951 9504
AR 5214 4808
ARCN1 4082 6402
AREG 4465 7165
ARF1 8465 9910
ARF3 5651 9049
ARF4 9859 9444
ARF5 5736 9180
ARFGAP1 -6136 2991
ARFGAP2 -8987 2096
ARFGAP3 -6040 5157
ARRB1 -4581 4541
ARRB2 7827 9274
ARSA -218 5556
ARSB 8124 8067
ARSD 8118 8210
ARSG -5202 -1774
ARSJ -1176 -6399
ARSK -8263 -10357
ASB1 -7632 6070
ASB13 3848 3880
ASB14 4303 -4544
ASB16 -8746 -2220
ASB2 -10926 -8940
ASB3 4105 1485
ASB4 -5055 -4525
ASB6 -7877 2463
ASB7 7450 6094
ASB8 823 6079
ASB9 4472 -207
ASGR1 9847 9456
ASGR2 10000 10129
ASXL1 -6957 -9295
ASXL2 -1697 3477
ATXN3 5521 599
ATXN7 6293 -3592
AURKA -542 4483
AURKB -4097 3408
AXIN1 -10901 -2157
AXIN2 1014 -9374
B3GALNT2 765 622
B3GLCT -10606 -8784
B3GNT2 5152 5953
B3GNT4 -8399 -9205
B3GNT5 10030 8205
B3GNT7 -11219 -9428
B3GNT8 9251 9421
B3GNT9 4813 -5292
B3GNTL1 6 7067
B4GALNT2 -601 2343
B4GALT1 -4177 7099
B4GALT2 -7253 -2349
B4GALT3 -9162 -7981
B4GALT4 -9971 3971
B4GALT5 8862 9469
B4GALT6 -10936 -1047
B4GAT1 -4385 -4229
BABAM1 -6080 3440
BAP1 -8830 5447
BARD1 -8030 184
BCL10 6467 6003
BECN1 6040 6760
BET1 7030 -4395
BET1L -7832 -2582
BGLAP 819 -1590
BIRC2 8079 3449
BIRC3 -2270 -11079
BIRC5 2725 4169
BLM -2847 -3960
BMI1 -3862 -8689
BRCA1 8071 6505
BRCC3 7957 6103
BST1 10108 9972
BTBD1 6622 1719
BTBD6 -7724 -284
BTRC -6845 -441
C1GALT1 1726 -3586
C1GALT1C1 8882 8311
C3 -11179 -10489
C4A 5060 4740
CALM1 -6645 1321
CALR 6685 6374
CALU 9106 7766
CAMKMT 6048 -981
CAND1 3497 -7234
CANX 6838 5751
CAPZA1 8666 8511
CAPZA2 9698 8474
CAPZB 6100 8926
CASP8AP2 -565 -10849
CBX2 -6781 -1304
CBX4 -7121 4998
CBX5 -4225 -8724
CBX8 6588 5926
CCDC22 1981 8158
CCDC8 6938 -2578
CCNA1 1826 474
CCNA2 1795 1560
CCNF -10194 -4195
CCP110 5497 1580
CD109 5339 4477
CD52 -5003 -406
CD55 9326 9842
CD59 4075 5772
CDC20 -74 5136
CDC25A 3970 2814
CDC34 8212 9329
CDC73 5065 5233
CDCA8 -4836 412
CDK1 4994 -360
CDKN2A -3659 -3958
CETN2 6907 5515
CFP 6744 8615
CHD3 -9446 -6383
CHM 3845 3159
CHML 5118 -3431
CHST10 -11043 -8384
CHST8 2634 6673
CISH 9673 299
CKAP4 10101 9674
CLSPN 4958 3125
CMAS 9548 8906
CNIH1 9316 7116
CNIH2 701 601
CNIH3 -8173 -6989
COG1 -10399 -10838
COG2 -1210 -5915
COG3 3891 -5333
COG4 -4813 2002
COG5 1617 -3368
COG6 1512 -6280
COG7 2191 6149
COG8 -2814 2839
COL7A1 3993 7683
COMMD1 6175 5987
COMMD10 7526 3203
COMMD2 5023 3219
COMMD3 1068 -670
COMMD4 -7833 871
COMMD5 3387 6513
COMMD6 942 -555
COMMD7 979 6845
COMMD8 8929 6796
COMMD9 8869 7706
COPA 7617 9591
COPB1 8213 7283
COPB2 8531 8034
COPE 365 8719
COPG1 2542 9195
COPG2 7905 8313
COPS2 8864 5037
COPS3 7364 5716
COPS4 1748 2715
COPS5 3882 5135
COPS6 -3920 4485
COPS7A 1707 8090
COPS7B -9179 -6481
COPS8 -1206 -8494
COPZ1 2549 5017
COPZ2 -9229 -9247
CP -4947 388
CPM 7659 7193
CREBBP -4951 6023
CSF1 196 -1673
CSNK1D -10030 6117
CST3 1960 3081
CTBP1 -10319 2597
CTR9 2564 4136
CTSA 10083 10131
CTSC -7528 5285
CTSZ 8972 9860
CUL1 -2085 -10951
CUL2 6801 1682
CUL3 7151 7368
CUL4A 417 -2398
CUL4B 4392 3352
CUL5 7502 -2980
CUL7 -8296 2248
CUL9 -6452 -2962
CYLD 2995 -11046
DAD1 5534 6325
DAG1 -8464 -2147
DAXX -10506 -3361
DCAF10 6518 5106
DCAF11 -9260 2252
DCAF13 -3380 -2910
DCAF16 -7938 -10787
DCAF17 -6900 -10369
DCAF4 -7031 -10627
DCAF5 -10760 -125
DCAF6 8820 8847
DCAF7 -4647 2263
DCAF8 -8640 -7396
DCTN1 -5984 7873
DCTN2 8504 10012
DCTN3 325 7904
DCTN4 7967 9572
DCTN5 -7505 664
DCTN6 7871 7759
DCUN1D1 8986 5618
DCUN1D2 -2636 -3009
DCUN1D3 1597 5396
DCUN1D4 3074 -10782
DCUN1D5 3584 1371
DDA1 -6241 6337
DDB1 -2944 5557
DDB2 -9012 -10384
DDOST 459 8249
DDX17 -2678 -5554
DDX5 -8723 -7926
DDX58 -10158 -10278
DERL1 -8912 -3885
DERL2 4947 3337
DHDDS -7112 3558
DHPS -2392 3110
DNAJC24 -3885 -10535
DNAJC3 9077 8882
DNMT1 -10726 -10916
DNMT3A -3948 -310
DNMT3B 5487 4173
DOHH -3151 1163
DOLK -6603 967
DOLPP1 3438 3524
DPAGT1 6056 1306
DPH1 -8051 -10630
DPH2 -7140 -9731
DPH3 9097 7392
DPH5 3102 395
DPH6 -967 -8206
DPH7 -9088 -8668
DPM1 3623 1708
DPM2 4659 5141
DPM3 -3178 5487
DTL 2723 -661
DYNC1H1 -8881 -2533
DYNC1I1 7141 2722
DYNC1I2 8160 8196
DYNC1LI1 7894 6997
DYNC1LI2 3494 5636
DYNLL1 6026 6499
DYNLL2 -6325 -225
EDEM1 3521 253
EDEM2 8210 9514
EDEM3 9762 8422
EEF1A1 53 -4688
EEF2 -2498 2707
EEF2KMT -8913 -5991
EID3 -10177 -10260
EIF5A 1424 1809
EIF5A2 -10605 -9068
ELOB 4867 8716
ELOC 6598 8484
ENAM 731 -2171
ENGASE -5841 -6317
EP300 4311 7552
EPAS1 5959 8551
ERCC8 2277 4188
ESR1 -6046 -8495
ETFB 6243 9120
ETFBKMT 5689 1933
F5 10084 10070
F8 7498 7167
FAM20A 10078 10142
FAM20C 9723 10066
FBN1 5230 4463
FBXL12 -4301 2284
FBXL13 2462 5869
FBXL14 -6789 -2829
FBXL15 1462 6096
FBXL16 2754 -10861
FBXL18 -5426 6339
FBXL19 7149 9883
FBXL20 6138 5443
FBXL22 -8336 -7072
FBXL3 2372 1555
FBXL4 8476 5165
FBXL5 10052 9713
FBXL8 6606 3297
FBXO10 -9543 -2014
FBXO11 8518 6652
FBXO15 -57 -1454
FBXO17 6660 2069
FBXO2 -8087 -5594
FBXO21 -8475 -8331
FBXO22 4093 -5449
FBXO27 -4715 -3768
FBXO30 5887 4626
FBXO31 -10431 -10713
FBXO32 -9356 -10029
FBXO4 -7804 -11129
FBXO40 -216 3482
FBXO41 -3899 1696
FBXO44 -7880 -8023
FBXO6 -7080 1208
FBXO7 9298 6606
FBXO9 10081 9997
FBXW11 4585 7364
FBXW12 -7896 -6549
FBXW2 544 8055
FBXW4 -10467 -8565
FBXW5 -9273 5091
FBXW7 -5277 -3657
FBXW8 -9427 -6871
FBXW9 -10047 -416
FCGR3B 4203 4625
FCSK -1802 4404
FEM1A -4359 4720
FEM1B 6843 4121
FEM1C 5709 4915
FGF23 -3924 -7953
FKBP8 9424 8644
FN1 10003 6211
FN3K 6996 2744
FN3KRP -8874 -9906
FOLR2 2768 -6707
FOXK1 -7786 -1031
FOXK2 -2626 6074
FOXO4 -615 8296
FPGT 8997 6942
FSTL1 9009 8495
FSTL3 9845 9861
FUCA1 8013 8533
FUCA2 9577 7885
FUOM -3125 -3604
FURIN 8111 10053
FUT8 -7539 -7706
GALNT1 7249 6590
GALNT10 -10147 3215
GALNT11 -4476 780
GALNT12 -4955 -9921
GALNT14 8541 9404
GALNT15 -933 1061
GALNT16 1320 1110
GALNT2 8571 9697
GALNT3 -9370 4339
GALNT4 7705 7292
GALNT5 -1520 -429
GALNT6 291 420
GALNT7 8901 9243
GALNT8 -1857 -7569
GALNT9 -2617 -10483
GAN 203 -1098
GANAB -8512 4203
GAS6 6462 9517
GATA3 -10441 -11237
GBF1 -8933 1807
GCNT1 8143 9126
GCNT3 6315 4814
GCNT4 -1533 -11256
GCNT7 1274 3358
GFPT1 -24 -5649
GFPT2 -9716 -7397
GGCX 4204 6743
GLB1 9091 9091
GMDS 4877 5289
GMPPA 1299 5440
GMPPB -7578 -3166
GNE -484 -3839
GNPNAT1 4439 -10903
GOLGA2 -878 8019
GOLGB1 -242 -5768
GOLM1 -6550 -4069
GORASP1 7651 6560
GOSR1 -4021 2971
GOSR2 -2437 1468
GPAA1 -2080 8059
GPLD1 -8412 -4818
GPS1 -8718 1571
H2AC11 7852 7819
H2AC20 -790 6112
H2AC6 8700 8169
H2AW -10705 -7332
H2BC11 8424 8288
H2BC12 9066 9812
H2BC15 3036 6455
H2BC17 7882 7312
H2BC18 4771 8130
H2BC21 9852 9656
H2BC4 7156 7805
H2BC5 7596 8773
H2BC9 7965 4715
H2BU1 -6349 -3895
HCFC1 1469 5667
HDAC1 -3835 3708
HDAC2 8973 3999
HDAC4 9329 9546
HDAC7 4750 7247
HERC2 -10344 -6770
HGS -381 6840
HIC1 -11023 -899
HIF1A 7330 7808
HIF3A -7283 927
HIPK2 -4431 8857
HLA-A -5067 570
HLA-B -1559 1570
HLTF -4927 -10182
HNRNPC 5157 7435
HNRNPK 7811 7654
HSP90B1 7042 372
HSPA8 -8286 -8908
ICMT -3792 2455
IDE 8765 6765
IFIH1 -6483 -10093
IGFBP3 -8608 -8989
IGFBP4 -8033 -4877
IGFBP7 -5162 9129
IKBKE 387 6793
IKBKG -3058 7903
IL33 -438 931
INCENP -9437 323
ING2 5186 4738
INO80 -9571 -1988
INO80B -9043 3286
INO80C 8592 5840
INO80D -4577 -3233
INO80E -8182 -4991
ITIH2 -9205 -3427
JOSD1 -8246 4503
JOSD2 4043 9627
KAT2A -6742 -10405
KAT2B 116 -1532
KBTBD6 -1477 2862
KBTBD7 3626 6975
KBTBD8 -1867 -3245
KCTD6 4870 5068
KCTD7 -9176 -10293
KDELR1 9552 9681
KDELR2 8771 7531
KDELR3 2255 -3318
KDM1B 6297 4922
KEAP1 -3358 7274
KIN 3382 4220
KLHL11 -2734 -5716
KLHL2 9929 9615
KLHL20 -9314 -9256
KLHL21 663 6548
KLHL22 -10423 -8088
KLHL25 -9206 -9406
KLHL3 -8309 -11239
KLHL42 -4575 -7103
KLHL5 9255 2537
KLHL9 1973 2194
KTN1 7536 1922
L3MBTL2 -9641 -6612
LAMB1 2797 7716
LAMB2 3126 -317
LAMC1 9628 10118
LARGE1 -4555 -5687
LARGE2 2566 -5756
LEO1 6728 -1045
LGALS1 8011 10042
LMAN1 -1255 -10522
LMAN2 2397 8522
LMAN2L 7675 6680
LMO7 -3935 -10042
LRR1 -7801 -3939
LRRC41 5384 8643
LSAMP 2156 1709
LTBP1 9092 8408
LY6E -10979 -10846
LYPD2 -11077 -6235
LYPD3 -6190 -6500
LYPD5 -6874 -3793
MAGT1 574 3711
MAN1A1 4965 9297
MAN1A2 -1459 -993
MAN1B1 -7203 -495
MAN1C1 1436 -8761
MAN2A1 5542 -2948
MAN2A2 1864 8354
MANEA 6711 -5721
MAP3K7 1546 4274
MARCHF6 -3247 -1277
MAT2B -6654 -7646
MAVS 6465 9067
MBD1 -1461 4147
MBD5 -3573 4398
MBD6 7308 8746
MBTPS1 1704 4208
MCFD2 7963 7485
MCRS1 -9376 -1787
MDC1 -10561 -10461
MDGA1 -4452 -3553
MDM2 7204 3892
MDM4 4169 -2541
MELTF 2745 8465
MEN1 -8589 -4575
METTL21A 4851 4496
METTL22 -1028 7942
MFGE8 -535 4090
MGAT1 2229 8361
MGAT2 -5319 4067
MGAT3 2892 -5080
MGAT4A -3305 -4301
MGAT4B 9276 9187
MGAT4C 3599 -4032
MGAT5 -5440 -102
MIA2 6640 5566
MIA3 3397 -6425
MITF 9802 9484
MLEC 1226 3680
MOGS -5970 1434
MPDU1 7358 8337
MPI -6079 -9414
MRTFA 7793 9266
MSLN -8481 3943
MTA1 -550 -1521
MUC1 8159 7011
MUC12 -8506 -9690
MUC16 377 -5584
MUC20 -2625 -6328
MUC4 643 -4710
MUC5B -8416 -622
MUC6 -3460 -1745
MUCL1 -1878 -1414
MUL1 -4019 5276
MVD -10176 2670
MXRA8 -5732 -6638
MYC 8429 -2186
MYSM1 -2988 -7508
NAE1 -6037 -10474
NAGK 6329 2553
NANP -8562 -6438
NANS 8296 8165
NAPA -2447 3305
NAPB -291 -2004
NAPG 7409 3591
NCOA1 -1753 6268
NCOA2 -4443 3788
NCOR2 4843 9646
NDC1 -9151 -11223
NEDD8 -156 8587
NEGR1 1134 2142
NEU1 9336 9571
NEU3 -1390 -1896
NEURL2 -6006 -329
NFKB2 3069 -1167
NFKBIA 6855 7374
NFRKB -4887 950
NGLY1 -86 -2388
NICN1 -5684 1539
NLRP3 9708 8944
NOD1 -10930 -10348
NOD2 9408 8613
NOP58 3298 -10545
NPL 10063 10123
NPM1 306 -10502
NR1H2 4003 8448
NR1H3 -8939 2196
NR2C1 -5368 -9461
NR3C1 -5002 2698
NR3C2 -6020 -10768
NR4A2 -4347 3
NRIP1 4155 5430
NRN1 8397 9179
NRN1L -7189 -5742
NSF 8895 9680
NSMCE1 4738 7075
NSMCE2 5069 6823
NSMCE3 -10366 -8394
NSMCE4A -9103 -9613
NTNG2 -2845 6248
NUB1 -10205 -10007
NUCB1 8538 9717
NUDT14 -3679 -4528
NUP107 -4463 -10317
NUP133 -4339 -4616
NUP153 -7195 -2408
NUP155 -4644 -9292
NUP160 -2518 -10020
NUP188 -9467 -9810
NUP205 -8533 -9667
NUP210 -10480 -5943
NUP214 8588 8152
NUP35 -4281 -10256
NUP37 3188 3613
NUP42 1567 -5400
NUP43 -55 -10161
NUP50 6614 4617
NUP54 2794 -9194
NUP58 9637 9212
NUP62 3053 1921
NUP85 1119 -2732
NUP88 -7116 -10078
NUP93 -9095 -8944
NUP98 208 4310
NUS1 9194 7298
OBSL1 -10027 2453
OGT -3036 -7273
OS9 8889 9708
OTUB1 -5323 4596
OTUB2 44 -533
OTUD3 -6891 -9799
OTUD5 -9093 2293
OTUD7A -10002 -9866
OTUD7B -11017 -9453
OTULIN 3200 -288
P4HB 6474 9641
PAF1 -5217 5851
PARK7 4896 7394
PARP1 -10438 -8545
PCGF2 -3955 -2094
PCNA 613 -5415
PDIA3 2037 4838
PDIA6 7671 5364
PEX10 -9614 1012
PEX12 -6667 -7170
PEX13 4317 285
PEX14 -9676 6797
PEX2 287 4591
PEX5 -1877 5897
PGAP1 7057 -10862
PGM3 7906 -5172
PHC1 -5034 -8115
PHC2 8426 9918
PHC3 -3083 -7777
PIAS1 9212 7268
PIAS2 -2649 -6975
PIAS3 -3766 1150
PIAS4 -1432 8309
PIGA -995 -6961
PIGB 2518 4698
PIGC 1841 -303
PIGF 8088 7114
PIGG -6117 -6858
PIGH -8202 -6648
PIGK -4713 -3776
PIGL -9453 -10803
PIGM 4550 -642
PIGN 3457 3051
PIGO -9860 -3302
PIGP 2426 -5745
PIGQ -2492 4360
PIGS 1889 8350
PIGT -5131 3913
PIGU -227 -8489
PIGV -7824 3121
PIGW -9044 -10468
PIGX 8092 4615
PIGZ -2842 5053
PLAUR 8428 9009
PML -6449 -6720
PMM1 -3254 6102
PMM2 7431 -439
PNPLA2 9239 9613
POFUT2 -8902 -9091
POLB 410 -7278
POM121 -8969 -3230
POM121C -9525 -1010
POMGNT1 -10525 -9638
POMGNT2 -8918 2070
POMK -4122 302
POMT1 -3743 -8982
POMT2 -619 2396
PPARA -791 2682
PPARG 10111 10137
PPARGC1A 7923 1692
PPP6C 8559 6316
PPP6R1 -5320 7658
PPP6R3 3008 3925
PREB -1638 8142
PRKCSH -3697 7582
PRKDC -8444 -7899
PRMT3 7417 -1287
PROC -10857 -3490
PROS1 9065 7937
PROZ 174 -4404
PRSS21 759 -836
PRSS23 -11252 -8805
PSMA1 8278 7406
PSMA2 5830 5666
PSMA3 4646 -7621
PSMA4 3950 -1036
PSMA5 -2119 -3983
PSMA6 6893 5865
PSMA7 3550 8554
PSMB1 3915 4224
PSMB10 -7878 -1272
PSMB2 2664 4928
PSMB3 4971 8382
PSMB4 -3175 4911
PSMB5 6561 9138
PSMB6 1312 8784
PSMB7 8034 9051
PSMB8 -4481 75
PSMB9 -9105 -10433
PSMC1 6759 7782
PSMC2 -2524 4517
PSMC3 -4971 4984
PSMC4 -10757 -336
PSMC5 -3424 2764
PSMC6 8812 6000
PSMD1 7679 7587
PSMD10 2067 2450
PSMD11 6914 6824
PSMD12 9011 5710
PSMD13 3157 7205
PSMD14 2891 3041
PSMD2 4352 8396
PSMD3 -2243 6367
PSMD4 6858 9449
PSMD5 2770 4781
PSMD6 8841 8304
PSMD7 6534 6147
PSMD8 739 7117
PSMD9 3580 9001
PSME1 -7256 -7913
PSME2 -5548 -10355
PSME3 9120 8239
PSME4 -5205 -3127
PSMF1 6709 6770
PTEN 9191 8752
PTP4A2 714 3952
PTRH2 9404 1694
PUM2 2582 -1706
QSOX1 9451 10048
RAB10 9303 9477
RAB11A 9786 8252
RAB11B -3172 6936
RAB12 5316 -2681
RAB13 10014 10088
RAB14 8215 7014
RAB15 -6713 -3173
RAB18 9425 7287
RAB19 -4588 4873
RAB1A 9700 9407
RAB1B 5676 9455
RAB20 8490 9234
RAB21 7222 6309
RAB22A -3504 -1333
RAB23 4069 39
RAB24 2905 6201
RAB26 2250 -7181
RAB27A 9164 8675
RAB27B -847 4689
RAB29 -10737 -4912
RAB2A 9085 9113
RAB2B -5115 -7189
RAB30 -7367 -8558
RAB31 9956 9895
RAB32 10006 10036
RAB33A -10854 -5029
RAB33B 8756 6897
RAB34 8570 9028
RAB35 -6982 6352
RAB36 651 6588
RAB37 -11095 -6455
RAB38 -10061 -3007
RAB39A 8587 6613
RAB39B -9791 -9905
RAB3A 7816 8757
RAB3B -3348 -1420
RAB3D 9596 9946
RAB40B -8198 -11061
RAB40C 6619 9309
RAB41 -20 -4213
RAB42 -2106 5881
RAB43 4478 7506
RAB44 4572 -693
RAB4A 9473 7027
RAB4B -7808 7089
RAB5A 8478 6815
RAB5B 3295 7820
RAB5C 7846 9422
RAB6A 8487 8616
RAB6B 6925 6712
RAB7A 8897 9367
RAB7B -7654 2220
RAB8A 540 5295
RAB8B 6227 7055
RAB9A 2889 5200
RAB9B -5682 -4620
RABGGTA -5925 1157
RABGGTB 5217 -8376
RAD18 -9629 -11080
RAD21 3724 1987
RAD23A 7262 6302
RAD23B 9180 9565
RAD52 3180 -1444
RAE1 4777 6291
RANBP2 4453 -2222
RANGAP1 -10259 -9220
RARA -356 8119
RBBP5 4931 173
RBBP7 -10846 -9848
RBX1 1418 4877
RCE1 -3787 -2010
RCN1 -7373 -9138
RECK 146 -9535
RELA -7305 2739
RENBP 6011 7767
RFT1 7279 3586
RHOA 8351 8888
RHOT1 10010 9811
RING1 -6720 548
RIPK1 -10879 -4699
RIPK2 1665 2297
RNF103 -5944 2
RNF123 3943 8163
RNF135 8493 9341
RNF139 1735 3515
RNF144A -8522 -10220
RNF146 8442 9760
RNF152 5182 2967
RNF168 -8794 648
RNF181 3911 7149
RNF185 3476 7488
RNF2 5589 3400
RNF20 5931 6804
RNF40 363 8641
RNF5 -8439 -1294
RNF7 6703 8617
RORA -10511 -10952
RPA1 -10457 -9792
RPN1 7629 8737
RPN2 5890 7636
RPS2 -6072 -1316
RPS27A -3555 -7070
RRAGA -920 7747
RTF1 1518 4233
RTN4RL1 5909 -639
RTN4RL2 4129 8407
RUVBL1 -5940 -5741
RWDD3 5206 -1627
RXRA 6327 8932
SAE1 -9557 -1648
SAFB 638 4869
SAR1B 8795 5984
SATB1 -455 -8786
SATB2 8345 6299
SBSPON -553 -8704
SCFD1 4551 3924
SCMH1 2787 -7207
SDC2 7232 4710
SEC13 2125 6861
SEC16A -2929 6748
SEC16B -1454 1213
SEC22A 374 -4424
SEC22B 8663 4943
SEC22C -2377 -1611
SEC23A 8776 6905
SEC23IP 5231 -574
SEC24A 8318 7788
SEC24B 1663 5398
SEC24C -9662 3561
SEC24D 8017 8795
SEC31A 1743 2474
SEH1L 7189 -8511
SEL1L 7157 7252
SELENOS -4119 1116
SEM1 993 5942
SEMA5A -7754 -9477
SEMA5B -1476 3843
SENP1 -8006 -3664
SENP2 5008 4389
SENP5 -824 -5825
SENP8 7374 893
SERPINA1 9571 9817
SERPINA10 4955 3958
SERPIND1 -5478 -489
SHISA5 -7800 3831
SHPRH -4011 -8036
SIAH2 9783 8092
SIN3A -9037 -7770
SKP1 8120 2700
SKP2 -2615 -7161
SLC17A5 3558 5793
SLC35A1 9102 6415
SLC35C1 1561 3694
SMAD1 7656 9731
SMAD2 5238 5871
SMAD3 -10084 -10081
SMAD4 -3009 -6696
SMAD7 -11234 -5230
SMC1A -2815 3295
SMC3 6086 -4018
SMC5 3643 -9046
SMC6 729 -4517
SMURF2 -9128 -7045
SNX3 9914 9837
SOCS2 4901 -4080
SOCS3 9830 10110
SOCS5 6009 2808
SOCS6 8906 9207
SP100 5494 4353
SP3 7059 5694
SPON1 -5400 -9627
SPON2 -11244 -8318
SPRN -7133 -9252
SPSB1 -2844 4000
SPSB2 -9283 1413
SPSB3 -8986 -388
SPTA1 9470 6216
SPTAN1 -10174 -8889
SPTB 9958 9302
SPTBN1 -6572 -6164
SPTBN2 -5447 -3871
SPTBN5 -7557 -461
SRD5A3 3417 4347
ST3GAL1 -6884 -3859
ST3GAL2 7832 9657
ST3GAL3 2775 828
ST3GAL4 -9921 7993
ST3GAL5 -8483 -10211
ST3GAL6 9317 5155
ST6GAL1 -10673 -10107
ST6GAL2 -6498 1859
ST6GALNAC1 1128 -7500
ST6GALNAC2 6233 7200
ST6GALNAC3 8893 9823
ST6GALNAC4 -4762 1735
ST6GALNAC6 -10863 -9916
ST8SIA1 160 -9368
ST8SIA4 9016 8665
ST8SIA5 317 2482
ST8SIA6 -10982 -6606
STAG1 -6902 -2525
STAG2 7287 5015
STAM 3046 2017
STAM2 8115 5912
STAMBP -1020 4263
STAMBPL1 -5729 -9607
STS 1348 5281
STT3A 3820 5008
STX17 -4480 -10772
STX5 3566 8258
SUDS3 6591 4895
SUMF1 9162 9651
SUMF2 -10998 -8612
SUMO1 7968 6798
SUMO2 6089 5153
SUMO3 6805 7483
SUZ12 4539 -3535
SYVN1 734 2029
TAB1 6623 5746
TADA2B 4725 7618
TADA3 -1163 9039
TAF10 2322 8682
TAF9B 6761 -6403
TBC1D20 -6556 3818
TDG 8035 6656
TECTA -8588 -1298
TF 1794 1244
TFG 8930 6725
TFPT 1573 7442
TGFA 7935 9686
TGFB1 -2566 6745
TGFBR1 -7960 3224
TGFBR2 -5037 6173
TGOLN2 8606 9683
THBS1 1778 8102
THRA -9647 -866
THRB -1682 3605
THSD1 -3671 -6837
THSD4 -4394 -1859
THSD7A -6799 -6728
TIMP1 6136 9944
TMED10 35 2168
TMED2 6426 6360
TMED3 -2098 4751
TMED7 9038 7918
TMED9 917 9007
TMEM115 31 6881
TMEM129 345 5404
TMEM132A 6765 4841
TNC -1334 -4015
TNFAIP3 -10682 -6292
TNIP1 6944 9401
TNIP2 -1490 7359
TNIP3 -8226 -6253
TNKS -7769 -6024
TNKS2 604 1179
TOMM20 6504 -4519
TOMM70 -2701 -7580
TOP1 9095 7736
TOP2A 2516 2007
TOP2B 1474 -1831
TOPORS 4682 2877
TP53 -7284 -8934
TP53BP1 -7310 -9882
TPGS1 -2382 6645
TPGS2 -4317 -763
TPR -1066 -7983
TPST1 9124 9903
TPST2 -8995 8264
TRAF2 -9898 -9879
TRAF3 2694 -5265
TRAF6 -1767 2089
TRAPPC1 5277 9110
TRAPPC10 -10478 -2812
TRAPPC2 -8890 -5344
TRAPPC2L -350 -932
TRAPPC3 6827 7922
TRAPPC4 -7161 -2663
TRAPPC5 4081 6280
TRAPPC6A -7665 -10218
TRAPPC6B 6230 4019
TRAPPC9 921 7473
TRIM13 -969 -1503
TRIM25 8976 8487
TRIM27 9047 8593
TRIM28 -4783 -1562
TRRAP -7730 -2671
TSTA3 6432 6332
TTL 1207 -3562
TTLL1 -6316 -4940
TTLL11 -4397 -2844
TTLL12 2186 6431
TTLL13P -10308 -2008
TTLL3 -6915 1425
TTLL4 9103 7623
TTLL5 -7569 481
TTLL7 8840 5402
TUBA1A 6178 7845
TUBA1B 1572 6394
TUBA1C 7082 7744
TUBA3D -4511 -9736
TUBB1 6239 6225
TUBB2A 8108 9349
TUBB3 -1306 3835
TUBB4A -6145 -8199
TUBB4B 6246 7789
TUBB6 1680 7491
TULP4 -4979 -1281
UAP1 -10828 -9681
UBA1 2505 8454
UBA2 1891 -5813
UBA3 9502 7030
UBA52 -1875 3023
UBA6 4933 3279
UBB 8251 6157
UBC -1915 5825
UBE2A 7726 8032
UBE2B 8648 6410
UBE2C 3717 5687
UBE2D1 9825 9491
UBE2D2 2673 5593
UBE2D3 9443 8783
UBE2E1 8528 6289
UBE2E3 5727 5064
UBE2F 960 8586
UBE2G1 3646 5958
UBE2G2 719 -9159
UBE2H 7660 8041
UBE2I -4201 2754
UBE2J2 7098 9468
UBE2K 8831 6196
UBE2L3 7416 7794
UBE2M 2776 9251
UBE2N 4087 2050
UBE2Q2 -8213 -9964
UBE2R2 8380 9338
UBE2S 3693 5680
UBE2T -2666 -8388
UBE2V2 6427 1996
UBE2W 9632 7147
UBE2Z -9598 -6520
UBXN1 -7382 5180
UBXN7 2090 2374
UCHL3 6245 65
UCHL5 -1550 -6617
UGGT1 2808 6596
UGGT2 7847 4069
UHRF2 -3722 -9636
UIMC1 9820 9822
USO1 6916 3905
USP10 8963 7208
USP11 -11165 -10441
USP12 8366 3679
USP13 -4013 -5427
USP14 -4406 -2591
USP15 8878 4964
USP16 1399 -8582
USP18 -10888 -10755
USP19 -8276 4372
USP20 -9609 -9844
USP21 -4240 -4963
USP22 5113 8715
USP24 -10050 -8289
USP25 5730 -1016
USP28 -11213 -9807
USP3 9151 9670
USP30 -296 2849
USP33 5005 -1397
USP34 -268 385
USP37 -7125 -9304
USP4 7420 8819
USP42 -10240 -7493
USP44 -2233 -7057
USP47 -3965 -1174
USP48 8881 3072
USP49 3927 2920
USP5 -7696 -412
USP7 5480 7173
USP8 8542 6497
USP9X 4318 6232
VCAN 10068 10125
VCP 3600 7754
VCPIP1 -736 1057
VCPKMT 1560 696
VDAC1 6643 4063
VDAC2 8674 7660
VDAC3 463 1981
VDR 7908 9387
VHL -212 6007
VNN1 9174 9668
VNN2 9583 9574
VNN3 5862 5923
WAC 380 7136
WDR20 -5900 2686
WDR48 -7124 -9778
WDR5 671 2111
WDR61 4426 -254
WDTC1 -5027 8434
WFS1 -9892 -5570
WRN -8612 -11220
WSB1 8808 8048
WSB2 7454 8057
XPC -9936 -8260
XPNPEP2 -11086 -9756
XRCC4 7049 7016
YKT6 -3724 6818
YOD1 8515 7196
YY1 -627 3060
ZBED1 -403 8068
ZBTB16 -9729 5951
ZNF131 -5951 -9975
ZNF350 -5482 -95
ZRANB1 4893 3821



Hemostasis

Hemostasis
metric value
setSize 542
pMANOVA 1.8e-22
p.adjustMANOVA 2.45e-20
s.dist 0.319
s.low.CRP 0.217
s.high.CRP 0.233
p.low.CRP 4.53e-18
p.high.CRP 1.78e-20




Top 20 genes
Gene low CRP high CRP
SIRPA 10106 10119
F12 10075 10096
F5 10084 10070
CYB5R1 9974 10035
NFE2 9979 10025
MAFG 10057 9928
GNA15 9871 10112
PRKACA 9885 10068
SERPINB2 10012 9937
ITGAM 9846 10065
CD36 10064 9814
GNG10 9939 9753
APLP2 9601 10056
PLA2G4A 9622 10024
GRB2 9631 9985
CLU 9512 10102
LHFPL2 9961 9629
MAPK14 9907 9606
QSOX1 9451 10048
ALDOA 9625 9857

Click HERE to show all gene set members

All member genes
low CRP high CRP
A1BG 5929.0 5909.0
A2M -7113.0 -9795.0
AAMP -5066.0 55.0
ABCC4 8425.0 7787.0
ABHD12 -10925.0 -3678.0
ABHD6 -8766.0 1990.0
ABL1 -6354.0 4467.0
ACTN1 9831.0 9585.0
ACTN4 -8606.0 8331.0
ADRA2A -416.0 4269.0
AK3 3805.0 293.0
AKAP1 -6703.0 -10750.0
AKAP10 8441.0 7768.0
AKT1 -4794.0 6231.0
ALB 1254.0 3551.0
ALDOA 9625.0 9857.0
ANGPT1 5647.0 1529.0
ANGPT2 -3015.0 -3425.0
ANGPT4 -7067.0 -1718.0
ANXA2 8647.0 9102.0
ANXA5 8914.0 8338.0
APBB1IP 9427.0 9201.0
APLP2 9601.0 10056.0
APOOL 5334.0 925.0
APP 9951.0 9504.0
ARRB1 -4581.0 4541.0
ARRB2 7827.0 9274.0
ATP1B1 -8715.0 -6224.0
ATP1B2 7770.0 5919.0
ATP1B3 -6365.0 2479.0
ATP2A1 -4808.0 -3244.0
ATP2A2 8393.0 8341.0
ATP2A3 -9252.0 3112.0
ATP2B1 -1673.0 -8000.0
ATP2B4 -10512.0 2227.0
BRPF3 -9358.0 -1215.0
BSG 9373.0 9841.0
C1QBP 3448.0 -906.0
CABLES1 -10654.0 -3980.0
CABLES2 -7456.0 -4892.0
CALM1 -6645.0 1321.0
CALU 9106.0 7766.0
CAP1 8192.0 8530.0
CAPZA1 8666.0 8511.0
CAPZA2 9698.0 8474.0
CAPZB 6100.0 8926.0
CARMIL1 -3253.0 -4453.0
CAV1 2492.0 1598.0
CBX5 -4225.0 -8724.0
CD109 5339.0 4477.0
CD177 9810.0 2861.0
CD2 -10446.0 -10590.0
CD244 -10734.0 -2835.0
CD36 10064.0 9814.0
CD44 8303.0 9047.0
CD47 -9758.0 -11025.0
CD48 1364.0 2569.0
CD58 6098.0 7272.0
CD63 8797.0 10079.0
CD74 -9610.0 -9737.0
CD84 6137.0 3333.0
CD9 9005.0 4476.0
CD99 6282.0 9411.0
CD99L2 4320.0 9759.0
CDC37L1 -228.0 -8385.0
CDC42 8498.0 7640.0
CDK2 -5388.0 -2127.0
CDK5 8395.0 9380.0
CEACAM1 8749.0 7909.0
CEACAM3 4583.0 7056.0
CEACAM6 8933.0 1336.0
CEACAM8 9111.0 1929.0
CENPE -3467.0 886.0
CFD 2998.0 2390.0
CFL1 5851.0 9242.0
CHID1 -2802.0 4694.0
CLEC1B 9832.0 8778.0
CLEC3B 8445.0 9345.0
CLU 9512.0 10102.0
CRK 9657.0 9429.0
CSK -5436.0 7707.0
CTSW -11085.0 -6320.0
CYB5R1 9974.0 10035.0
DAGLA -8692.0 -5866.0
DAGLB 3835.0 7615.0
DGKA 938.0 -9831.0
DGKD -9920.0 4546.0
DGKE -6514.0 -10998.0
DGKG 9648.0 7271.0
DGKH 4599.0 -5466.0
DGKK -10223.0 -7890.0
DGKQ -10016.0 -3011.0
DGKZ -9529.0 626.0
DOCK1 6941.0 8390.0
DOCK10 -4467.0 -10371.0
DOCK11 1877.0 4960.0
DOCK2 6433.0 8942.0
DOCK3 4726.0 -6915.0
DOCK4 7138.0 8517.0
DOCK5 7001.0 8497.0
DOCK6 3406.0 2473.0
DOCK7 3907.0 -3094.0
DOCK8 5584.0 6744.0
DOCK9 -6113.0 -10722.0
DOK2 -8963.0 4141.0
ECM1 6130.0 5365.0
EGF 9244.0 8355.0
EHD1 -7742.0 6425.0
EHD2 2628.0 7679.0
EHD3 4713.0 5570.0
ENDOD1 4364.0 3483.0
ESAM 8313.0 8096.0
F11R 8751.0 8489.0
F12 10075.0 10096.0
F13A1 9955.0 8516.0
F2R -10754.0 -3588.0
F2RL2 -5786.0 -419.0
F2RL3 3013.0 6077.0
F5 10084.0 10070.0
F8 7498.0 7167.0
FAM3C -7438.0 -8642.0
FCER1G 6595.0 9147.0
FERMT3 9331.0 9956.0
FGR 6254.0 9666.0
FLNA -8145.0 4196.0
FN1 10003.0 6211.0
FYN -10878.0 -6729.0
GAS6 6462.0 9517.0
GATA1 8650.0 9092.0
GATA2 -5266.0 -9369.0
GATA3 -10441.0 -11237.0
GATA6 -10906.0 -9307.0
GLG1 -6537.0 4671.0
GNA11 5883.0 2815.0
GNA12 4000.0 3840.0
GNA13 5622.0 6234.0
GNA15 9871.0 10112.0
GNAI1 6562.0 2097.0
GNAI2 5861.0 9258.0
GNAI3 9178.0 7726.0
GNAQ 10007.0 8976.0
GNAS 8297.0 8173.0
GNB1 6908.0 9175.0
GNB2 6587.0 9064.0
GNB3 7806.0 -8406.0
GNB4 9340.0 6537.0
GNB5 6182.0 -475.0
GNG10 9939.0 9753.0
GNG11 8239.0 6403.0
GNG2 -10761.0 192.0
GNG3 4993.0 -794.0
GNG4 414.0 -2445.0
GNG5 8894.0 9403.0
GNG7 -2881.0 -4054.0
GNG8 4092.0 4604.0
GNGT2 -11227.0 -6988.0
GP1BA 6335.0 6875.0
GP1BB 7053.0 8670.0
GP5 6641.0 -1822.0
GP6 7137.0 7699.0
GP9 7524.0 8518.0
GPC1 -6229.0 -1709.0
GRB14 3895.0 1183.0
GRB2 9631.0 9985.0
GTPBP2 1314.0 8197.0
GYPA 9185.0 7017.0
GYPB 9811.0 6933.0
GYPC 7971.0 6686.0
H3-3A 9297.0 9034.0
H3C15 5262.5 7402.5
HABP4 -5318.0 -10970.0
HBB 10013.0 8750.0
HBD 10072.0 9071.0
HBG1 9704.0 7230.0
HBG2 9860.0 7710.0
HDAC1 -3835.0 3708.0
HDAC2 8973.0 3999.0
HGF 9753.0 8929.0
HMG20B 2325.0 6041.0
HRAS -2248.0 -1932.0
HSPA5 8070.0 6713.0
IGHA1 4926.0 -5918.0
IGHA2 2335.0 -2345.0
IGHM 1890.0 -2470.0
IGHV1-2 5956.0 -3146.0
IGHV1-46 3766.0 -2976.0
IGHV1-69 2354.0 -2328.0
IGHV2-5 4451.0 -1972.0
IGHV2-70 -3315.0 -2159.0
IGHV3-11 3518.0 -4591.0
IGHV3-13 799.0 -2451.0
IGHV3-23 6032.0 -5092.0
IGHV3-30 2500.0 -5193.0
IGHV3-33 98.0 -4138.0
IGHV3-48 3183.0 -4340.0
IGHV3-53 3131.0 -1786.0
IGHV3-7 4185.0 -3630.0
IGHV4-34 1144.0 -4007.0
IGHV4-39 3786.0 -6542.0
IGHV4-59 4532.0 -5870.0
IGKC 2773.0 -6437.0
IGKV1-12 725.0 -6674.0
IGKV1-16 6217.0 -5451.0
IGKV1-17 -241.0 -2794.0
IGKV1-33 5955.0 -6384.0
IGKV1-5 6127.0 -5162.0
IGKV1D-39 5018.0 -2677.0
IGKV2-28 1440.0 -6662.0
IGKV2-30 5205.0 -5349.0
IGKV2D-28 -7224.0 -2947.0
IGKV3-11 5548.0 -7167.0
IGKV3-15 3174.0 -4687.0
IGKV3-20 3704.0 -5021.0
IGKV3D-20 -1830.0 -4618.0
IGKV4-1 2812.0 -4988.0
IGKV5-2 5226.0 -2682.0
IGLC1 -2813.0 -6176.0
IGLC2 -258.0 -6539.0
IGLC3 -2958.0 -4378.0
IGLC7 -3403.0 -4490.0
IGLV1-36 3522.0 -5030.0
IGLV1-40 163.0 -5497.0
IGLV1-44 4742.0 -5791.0
IGLV1-47 231.0 -6633.0
IGLV1-51 1708.0 -6601.0
IGLV10-54 -5422.0 316.0
IGLV2-11 870.0 -3205.0
IGLV2-14 -5127.0 -8197.0
IGLV2-18 2015.0 -2963.0
IGLV2-23 2029.0 -4201.0
IGLV2-8 4818.0 -5256.0
IGLV3-1 -96.0 -5140.0
IGLV3-12 -7299.0 -6816.0
IGLV3-19 4006.0 -5611.0
IGLV3-21 -975.0 -6062.0
IGLV3-25 -942.0 -5485.0
IGLV3-27 -5365.0 -4834.0
IGLV4-69 1344.0 -2261.0
IGLV5-45 4194.0 -7364.0
IGLV6-57 1834.0 -5837.0
IGLV7-43 4854.0 -2823.0
IGLV7-46 2445.0 -3619.0
IGLV8-61 -3989.0 -5208.0
INPP5D -10797.0 4515.0
IRF1 -6320.0 -7043.0
IRF2 6124.0 6880.0
ITGA1 9674.0 8579.0
ITGA10 5196.0 -2609.0
ITGA2 8852.0 -28.0
ITGA2B 9720.0 9409.0
ITGA3 -6696.0 -9714.0
ITGA4 -6795.0 -10195.0
ITGA5 6141.0 8618.0
ITGA6 3096.0 -8137.0
ITGAL -10958.0 -4334.0
ITGAM 9846.0 10065.0
ITGAV 7467.0 6188.0
ITGAX 3250.0 8762.0
ITGB1 3360.0 -108.0
ITGB2 8042.0 10007.0
ITGB3 9450.0 8690.0
ITIH3 598.0 -3824.0
ITIH4 -5812.0 -4898.0
ITPK1 1166.0 8412.0
ITPR1 -5546.0 -5368.0
ITPR2 6833.0 6418.0
ITPR3 -8438.0 -9066.0
JAK2 7618.0 374.0
JAM2 5523.0 -1757.0
JAM3 8836.0 5202.0
JAML 9043.0 8108.0
JCHAIN 4874.0 -8700.0
JMJD1C 7211.0 1437.0
KCNMA1 179.0 7498.0
KCNMB1 556.0 21.0
KCNMB3 4277.0 3244.0
KCNMB4 8339.0 6467.0
KDM1A -6245.0 -6064.0
KIF11 -140.0 1030.0
KIF13B 1563.0 7357.0
KIF15 -4399.0 -3471.0
KIF16B 4416.0 3004.0
KIF18A -5118.0 -1862.0
KIF18B -3932.0 1641.0
KIF19 -10944.0 -8869.0
KIF1B 8577.0 8548.0
KIF1C 6981.0 8811.0
KIF20A 5368.0 4706.0
KIF20B -962.0 -8226.0
KIF21A -10337.0 -10254.0
KIF21B -10698.0 -135.0
KIF22 -10995.0 -11246.0
KIF23 8000.0 4957.0
KIF26A -155.0 -6527.0
KIF26B -10618.0 -9336.0
KIF27 5469.0 1812.0
KIF28P -7127.0 -4560.0
KIF2A 2515.0 -1329.0
KIF2C 2032.0 104.0
KIF3A -9378.0 -11000.0
KIF3B 3757.0 4323.0
KIF3C 7590.0 9010.0
KIF4A -1703.0 4331.0
KIF5A -7037.0 -7903.0
KIF5B 9540.0 8103.0
KIF5C -2924.0 -10718.0
KIF6 2741.0 806.0
KIF9 -1185.0 6392.0
KIFAP3 -8849.0 -4476.0
KIFC1 -3213.0 1241.0
KIFC2 -900.0 -938.0
KLC1 1745.0 7386.0
KLC2 -6674.0 -7322.0
KLC3 8390.0 7398.0
KLC4 -9223.0 -3527.0
KLKB1 -3621.0 -9856.0
KRAS 3789.0 4070.0
L1CAM -1885.0 -5908.0
LAMP2 9608.0 8999.0
LAT -9843.0 -10628.0
LCK -10358.0 -10719.0
LCP2 -2426.0 872.0
LGALS3BP -5766.0 -10889.0
LHFPL2 9961.0 9629.0
LRP8 -1100.0 5967.0
LY6G6F 8519.0 8935.0
LYN 7575.0 8379.0
MAFF -7391.0 2653.0
MAFG 10057.0 9928.0
MAFK -5857.0 4438.0
MAGED2 -7650.0 1289.0
MANF 2669.0 2863.0
MAPK1 1052.0 9260.0
MAPK14 9907.0 9606.0
MAPK3 8931.0 9626.0
MERTK 7486.0 8872.0
MFN1 -1159.0 -3472.0
MFN2 1532.0 8255.0
MGLL 8873.0 7773.0
MICAL1 -41.0 8052.0
MIF -4739.0 -1332.0
MMP1 9240.0 6657.0
MMRN1 8473.0 8262.0
MPL -3027.0 4040.0
MYB 6506.0 -1852.0
NFE2 9979.0 10025.0
NHLRC2 -1125.0 -8298.0
NOS1 4727.0 -183.0
NOS3 5934.0 -5046.0
NRAS 7321.0 4878.0
OLA1 8253.0 3668.0
OLR1 8411.0 -2056.0
ORAI1 -9219.0 -1368.0
ORAI2 775.0 6855.0
ORM1 8665.0 8363.0
ORM2 -4938.0 149.0
P2RX1 7223.0 9888.0
P2RX4 7118.0 8994.0
P2RX5 2066.0 -1071.0
P2RX7 5741.0 3066.0
P2RY1 800.0 9467.0
P2RY12 5843.0 4889.0
PAFAH2 -11207.0 -9408.0
PCYOX1L 1442.0 -1806.0
PDE11A 4522.0 3010.0
PDE1B 3331.0 7142.0
PDE2A -4524.0 1659.0
PDE5A 7907.0 6484.0
PDE9A 1670.0 -9626.0
PDGFA 6115.0 5392.0
PDGFB -4645.0 -8897.0
PDPK1 2392.0 7816.0
PECAM1 8136.0 8308.0
PF4 6097.0 6609.0
PF4V1 -4280.0 3516.0
PFN1 -5663.0 7801.0
PHACTR2 4871.0 5821.0
PHF21A 9412.0 10047.0
PICK1 -7615.0 5643.0
PIK3CA 6889.0 4182.0
PIK3CB 9838.0 9248.0
PIK3CG -9742.0 5545.0
PIK3R1 -7197.0 -8942.0
PIK3R2 2459.0 5820.0
PIK3R3 -11107.0 -8159.0
PIK3R5 -9700.0 3911.0
PIK3R6 8267.0 7206.0
PLA2G4A 9622.0 10024.0
PLAT 6118.0 -4882.0
PLAU 1698.0 5458.0
PLAUR 8428.0 9009.0
PLCG1 -6360.0 -11043.0
PLCG2 -4618.0 6826.0
PLEK -7872.0 4766.0
PLG 1277.0 -2998.0
PPBP 7528.0 6376.0
PPIA -7248.0 -2108.0
PPIL2 -10280.0 -3054.0
PPP2CA 8810.0 8328.0
PPP2CB 8482.0 7631.0
PPP2R1A -3087.0 6994.0
PPP2R1B 2503.0 437.0
PPP2R5A -903.0 6957.0
PPP2R5B 5288.0 7952.0
PPP2R5C -10420.0 -7112.0
PPP2R5D -6508.0 4985.0
PPP2R5E 715.0 540.0
PRCP 8403.0 8843.0
PRKACA 9885.0 10068.0
PRKACB -9852.0 -10936.0
PRKAR1A 8455.0 9570.0
PRKAR1B 8879.0 7874.0
PRKAR2A 3755.0 7093.0
PRKAR2B 7943.0 7189.0
PRKCA 2473.0 1229.0
PRKCB 5395.0 8378.0
PRKCD 9393.0 9642.0
PRKCE -10383.0 -2720.0
PRKCH -11170.0 -10819.0
PRKCQ -10709.0 -10890.0
PRKCZ -10855.0 -7708.0
PRKG1 8854.0 5968.0
PRKG2 -7602.0 -7604.0
PROC -10857.0 -3490.0
PROCR -10182.0 -8277.0
PROS1 9065.0 7937.0
PRTN3 9645.0 4535.0
PSAP 7519.0 7770.0
PTGIR -8467.0 -6760.0
PTK2 7786.0 3481.0
PTPN1 -8327.0 7695.0
PTPN11 4691.0 6614.0
PTPN6 -691.0 7862.0
QSOX1 9451.0 10048.0
RAB27B -847.0 4689.0
RAB5A 8478.0 6815.0
RAC1 9052.0 9614.0
RAC2 -7677.0 6828.0
RACGAP1 3340.0 3770.0
RAD51B 4090.0 5955.0
RAD51C -4243.0 -6595.0
RAF1 8477.0 8327.0
RAP1A 8688.0 6973.0
RAP1B -2703.0 4941.0
RAPGEF3 1224.0 -2066.0
RASGRP1 -9849.0 -11029.0
RASGRP2 -7479.0 -7190.0
RBSN -7312.0 339.0
RCOR1 9795.0 9655.0
RHOA 8351.0 8888.0
RHOB -4807.0 3859.0
RHOG 7549.0 9255.0
S100A10 6664.0 7533.0
SCCPDH 8175.0 8195.0
SDC2 7232.0 4710.0
SDC3 3723.0 2630.0
SDC4 6516.0 7115.0
SELENOP -361.0 -9226.0
SELL 9694.0 9159.0
SELP 9499.0 8610.0
SELPLG -8513.0 7091.0
SERPINA1 9571.0 9817.0
SERPINB2 10012.0 9937.0
SERPINB6 3579.0 7946.0
SERPINB8 9836.0 9348.0
SERPIND1 -5478.0 -489.0
SERPINE1 7839.0 8101.0
SERPINE2 4786.0 6914.0
SERPINF2 -7666.0 -3830.0
SERPING1 -6329.0 -10968.0
SH2B1 -6398.0 -6874.0
SH2B2 4083.0 9454.0
SH2B3 3129.0 4903.0
SHC1 -3416.0 5815.0
SIN3A -9037.0 -7770.0
SIRPA 10106.0 10119.0
SIRPG -1621.0 -11085.0
SLC16A1 7992.0 3127.0
SLC16A3 7685.0 9834.0
SLC16A8 -6480.0 3682.0
SLC3A2 200.0 6877.0
SLC7A11 -6301.0 -3656.0
SLC7A5 -2245.0 4782.0
SLC7A6 2433.0 -8284.0
SLC7A7 7699.0 7341.0
SLC7A8 5188.0 -110.0
SLC8A1 9278.0 8733.0
SLC8A3 4564.0 690.0
SOD1 -1389.0 -3334.0
SOS1 3534.0 -7412.0
SPARC 9073.0 7195.0
SPN -11273.0 -10692.0
SRC -6857.0 -7229.0
SRGN 9312.0 9121.0
SRI 5491.0 7505.0
STIM1 -9148.0 7796.0
STX4 -7285.0 5736.0
STXBP2 9017.0 9835.0
STXBP3 9347.0 6785.0
SYK 9464.0 9848.0
SYTL4 8201.0 9013.0
TAGLN2 7953.0 7664.0
TBXA2R 6830.0 4756.0
TEX264 -10026.0 -2139.0
TF 1794.0 1244.0
TFPI -2186.0 -1679.0
TGFB1 -2566.0 6745.0
TGFB2 -8959.0 -4641.0
TGFB3 -7945.0 -6237.0
THBD 8726.0 9905.0
THBS1 1778.0 8102.0
TIMP1 6136.0 9944.0
TLN1 7865.0 9661.0
TMSB4X 6454.0 6825.0
TMX3 5784.0 -2953.0
TNFRSF10A 6128.0 171.0
TNFRSF10B 9578.0 8036.0
TNFRSF10D 10021.0 8559.0
TOR4A 8491.0 9893.0
TP53 -7284.0 -8934.0
TREM1 5997.0 7651.0
TRPC3 -9747.0 -5879.0
TRPC6 -4419.0 130.0
TSPAN7 7804.0 6540.0
TTN 1884.0 1350.0
TUBA4A 652.0 7677.0
VAV1 5553.0 8731.0
VAV2 -5033.0 -1339.0
VAV3 -6160.0 7203.0
VCL 7488.0 7955.0
VEGFA 8464.0 8215.0
VEGFB -7685.0 -5963.0
VPREB3 2631.0 -1523.0
VPS45 6527.0 1884.0
VTI1B 9177.0 8851.0
VWF 6949.0 7780.0
WDR1 -1705.0 8441.0
WEE1 -9903.0 -6012.0
YES1 -11138.0 -8566.0
YWHAZ 5165.0 5861.0
ZFPM1 -10935.0 -3498.0
ZFPM2 -7442.0 -7843.0



Platelet activation, signaling and aggregation

Platelet activation, signaling and aggregation
metric value
setSize 219
pMANOVA 2.66e-22
p.adjustMANOVA 3.3e-20
s.dist 0.465
s.low.CRP 0.252
s.high.CRP 0.39
p.low.CRP 1.25e-10
p.high.CRP 2.28e-23




Top 20 genes
Gene low CRP high CRP
F5 10084 10070
CYB5R1 9974 10035
GNA15 9871 10112
CD36 10064 9814
GNG10 9939 9753
APLP2 9601 10056
PLA2G4A 9622 10024
GRB2 9631 9985
CLU 9512 10102
LHFPL2 9961 9629
MAPK14 9907 9606
QSOX1 9451 10048
ALDOA 9625 9857
APP 9951 9504
ACTN1 9831 9585
SERPINA1 9571 9817
SYK 9464 9848
FERMT3 9331 9956
ITGA2B 9720 9409
CRK 9657 9429

Click HERE to show all gene set members

All member genes
low CRP high CRP
A1BG 5929 5909
A2M -7113 -9795
AAMP -5066 55
ABCC4 8425 7787
ABHD12 -10925 -3678
ABHD6 -8766 1990
ACTN1 9831 9585
ACTN4 -8606 8331
ADRA2A -416 4269
AKT1 -4794 6231
ALB 1254 3551
ALDOA 9625 9857
ANXA5 8914 8338
APBB1IP 9427 9201
APLP2 9601 10056
APOOL 5334 925
APP 9951 9504
ARRB1 -4581 4541
ARRB2 7827 9274
BRPF3 -9358 -1215
CALM1 -6645 1321
CALU 9106 7766
CAP1 8192 8530
CD109 5339 4477
CD36 10064 9814
CD63 8797 10079
CD9 9005 4476
CDC37L1 -228 -8385
CDC42 8498 7640
CFD 2998 2390
CFL1 5851 9242
CHID1 -2802 4694
CLEC1B 9832 8778
CLEC3B 8445 9345
CLU 9512 10102
CRK 9657 9429
CSK -5436 7707
CTSW -11085 -6320
CYB5R1 9974 10035
DAGLA -8692 -5866
DAGLB 3835 7615
DGKA 938 -9831
DGKD -9920 4546
DGKE -6514 -10998
DGKG 9648 7271
DGKH 4599 -5466
DGKK -10223 -7890
DGKQ -10016 -3011
DGKZ -9529 626
ECM1 6130 5365
EGF 9244 8355
ENDOD1 4364 3483
F13A1 9955 8516
F2R -10754 -3588
F2RL2 -5786 -419
F2RL3 3013 6077
F5 10084 10070
F8 7498 7167
FAM3C -7438 -8642
FCER1G 6595 9147
FERMT3 9331 9956
FLNA -8145 4196
FN1 10003 6211
FYN -10878 -6729
GAS6 6462 9517
GNA11 5883 2815
GNA12 4000 3840
GNA13 5622 6234
GNA15 9871 10112
GNAI1 6562 2097
GNAI2 5861 9258
GNAI3 9178 7726
GNAQ 10007 8976
GNB1 6908 9175
GNB2 6587 9064
GNB3 7806 -8406
GNB4 9340 6537
GNB5 6182 -475
GNG10 9939 9753
GNG11 8239 6403
GNG2 -10761 192
GNG3 4993 -794
GNG4 414 -2445
GNG5 8894 9403
GNG7 -2881 -4054
GNG8 4092 4604
GNGT2 -11227 -6988
GP1BA 6335 6875
GP1BB 7053 8670
GP5 6641 -1822
GP6 7137 7699
GP9 7524 8518
GRB2 9631 9985
GTPBP2 1314 8197
HABP4 -5318 -10970
HGF 9753 8929
HSPA5 8070 6713
ITGA2B 9720 9409
ITGB3 9450 8690
ITIH3 598 -3824
ITIH4 -5812 -4898
ITPR1 -5546 -5368
ITPR2 6833 6418
ITPR3 -8438 -9066
LAMP2 9608 8999
LAT -9843 -10628
LCK -10358 -10719
LCP2 -2426 872
LGALS3BP -5766 -10889
LHFPL2 9961 9629
LY6G6F 8519 8935
LYN 7575 8379
MAGED2 -7650 1289
MANF 2669 2863
MAPK1 1052 9260
MAPK14 9907 9606
MAPK3 8931 9626
MGLL 8873 7773
MMRN1 8473 8262
MPL -3027 4040
NHLRC2 -1125 -8298
OLA1 8253 3668
ORM1 8665 8363
ORM2 -4938 149
P2RY1 800 9467
P2RY12 5843 4889
PCYOX1L 1442 -1806
PDGFA 6115 5392
PDGFB -4645 -8897
PDPK1 2392 7816
PECAM1 8136 8308
PF4 6097 6609
PFN1 -5663 7801
PHACTR2 4871 5821
PIK3CA 6889 4182
PIK3CB 9838 9248
PIK3CG -9742 5545
PIK3R1 -7197 -8942
PIK3R2 2459 5820
PIK3R3 -11107 -8159
PIK3R5 -9700 3911
PIK3R6 8267 7206
PLA2G4A 9622 10024
PLCG2 -4618 6826
PLEK -7872 4766
PLG 1277 -2998
PPBP 7528 6376
PPIA -7248 -2108
PRKCA 2473 1229
PRKCB 5395 8378
PRKCD 9393 9642
PRKCE -10383 -2720
PRKCH -11170 -10819
PRKCQ -10709 -10890
PRKCZ -10855 -7708
PROS1 9065 7937
PSAP 7519 7770
PTK2 7786 3481
PTPN1 -8327 7695
PTPN11 4691 6614
PTPN6 -691 7862
QSOX1 9451 10048
RAB27B -847 4689
RAC1 9052 9614
RAC2 -7677 6828
RAF1 8477 8327
RAP1A 8688 6973
RAP1B -2703 4941
RAPGEF3 1224 -2066
RASGRP1 -9849 -11029
RASGRP2 -7479 -7190
RHOA 8351 8888
RHOB -4807 3859
RHOG 7549 9255
SCCPDH 8175 8195
SELENOP -361 -9226
SELP 9499 8610
SERPINA1 9571 9817
SERPINE1 7839 8101
SERPINF2 -7666 -3830
SERPING1 -6329 -10968
SHC1 -3416 5815
SOD1 -1389 -3334
SOS1 3534 -7412
SPARC 9073 7195
SRC -6857 -7229
SRGN 9312 9121
STX4 -7285 5736
STXBP2 9017 9835
STXBP3 9347 6785
SYK 9464 9848
SYTL4 8201 9013
TAGLN2 7953 7664
TBXA2R 6830 4756
TEX264 -10026 -2139
TF 1794 1244
TGFB1 -2566 6745
TGFB2 -8959 -4641
TGFB3 -7945 -6237
THBS1 1778 8102
TIMP1 6136 9944
TLN1 7865 9661
TMSB4X 6454 6825
TMX3 5784 -2953
TOR4A 8491 9893
TRPC3 -9747 -5879
TRPC6 -4419 130
TTN 1884 1350
TUBA4A 652 7677
VAV1 5553 8731
VAV2 -5033 -1339
VAV3 -6160 7203
VCL 7488 7955
VEGFA 8464 8215
VEGFB -7685 -5963
VTI1B 9177 8851
VWF 6949 7780
WDR1 -1705 8441
YWHAZ 5165 5861



Signaling by Receptor Tyrosine Kinases

Signaling by Receptor Tyrosine Kinases
metric value
setSize 408
pMANOVA 7.11e-22
p.adjustMANOVA 8.08e-20
s.dist 0.327
s.low.CRP 0.161
s.high.CRP 0.284
p.low.CRP 2.19e-08
p.high.CRP 6.76e-23




Top 20 genes
Gene low CRP high CRP
WASF1 10091 10132
GRB10 10103 10040
ATP6V0A1 9995 10010
PRKACA 9885 10068
LAMC1 9628 10118
ATP6V1A 9857 9880
CTNNA1 9646 10004
CYFIP1 9724 9912
GRB2 9631 9985
DUSP3 9937 9647
NCF4 9697 9856
FES 9556 9967
MAPK14 9907 9606
NCF2 9748 9694
RIT1 9696 9723
TNS3 9978 9419
ATP6V0D1 9444 9942
NCSTN 9503 9869
CLTC 9376 9720
CRK 9657 9429

Click HERE to show all gene set members

All member genes
low CRP high CRP
AAMP -5066 55
ABI1 6692 7709
ABI2 -7512 -9823
ADAM10 9314 9481
ADAM12 -3869 -4837
ADAM17 8058 9718
ADAP1 5460 8684
ADORA2A -4195 4298
AHCYL1 6114 7566
AKT1 -4794 6231
AKT2 -8391 5504
AKT3 -9616 -10833
ANOS1 4787 4405
AP2A1 -3194 9104
AP2A2 3196 9217
AP2B1 -9145 2444
AP2M1 7742 9334
AP2S1 7422 8877
APH1A -3379 6321
APH1B 6306 6678
APOE -5022 1771
AREG 4465 7165
ARF6 -2986 3785
ARHGEF7 -7925 1165
ATF1 7833 5463
ATF2 7002 164
ATP6AP1 2039 9790
ATP6V0A1 9995 10010
ATP6V0A2 -10623 -10379
ATP6V0B 8163 9396
ATP6V0C 9348 9734
ATP6V0D1 9444 9942
ATP6V0E1 8171 9289
ATP6V0E2 -8802 -11036
ATP6V1A 9857 9880
ATP6V1B2 9738 9281
ATP6V1C1 9888 8528
ATP6V1C2 2655 -3376
ATP6V1D 9600 9482
ATP6V1E1 8095 8397
ATP6V1E2 8322 4968
ATP6V1F 3461 6917
ATP6V1G1 5204 4277
ATP6V1G2 -4714 -10140
ATP6V1H 7942 8571
AXL -11042 -10904
BAIAP2 2620 -682
BAX 4717 7227
BRAF 276 2552
BRK1 5522 8298
CALM1 -6645 1321
CAV1 2492 1598
CBL 6620 8302
CDC37 -4604 7006
CDC42 8498 7640
CDK5 8395 9380
CDK5R1 -8396 3375
CHD4 -8254 587
CHEK1 3978 -4829
CILP -6679 -8991
CLTA 8416 8998
CLTC 9376 9720
COL4A2 1717 838
COL4A3 -2340 -3206
COL4A4 611 -3693
COL6A1 5798 -5980
COL6A2 -10166 -7673
COL6A3 8421 3878
COL9A2 -10833 -5976
COL9A3 8252 4215
CREB1 4878 -3476
CRK 9657 9429
CRKL 1263 5754
CSK -5436 7707
CTNNA1 9646 10004
CTNNB1 3201 7613
CTNND1 -4159 -7796
CUL5 7502 -2980
CYBA -48 8901
CYBB 9900 8910
CYFIP1 9724 9912
CYFIP2 -10558 -4935
DIAPH1 -9216 4270
DLG4 9905 8876
DNAL4 -697 5475
DNM1 6883 3239
DNM2 -6816 8202
DNM3 7927 7198
DOCK1 6941 8390
DOCK3 4726 -6915
DOCK7 3907 -3094
DUSP3 9937 9647
DUSP4 -6630 -4192
DUSP6 7994 2589
DUSP7 -4748 387
EGF 9244 8355
EGR1 5173 2023
EGR2 2394 -4615
EGR3 -4151 868
ELK1 -355 3195
ELMO1 4243 7282
ELMO2 -9506 6592
EP300 4311 7552
EPN1 5120 9372
EPS15 6185 4175
EPS15L1 -8354 6665
ERBB2 -11251 -9287
ERBB3 3021 -1481
ERBIN 2164 -118
EREG -837 3226
ESR1 -6046 -8495
ESRP2 -8071 -7011
FER 7034 -631
FES 9556 9967
FGF2 5967 3177
FGF22 -5885 -8493
FGF23 -3924 -7953
FGF7 158 -5338
FGF9 -8383 -6950
FGFBP2 -11279 -7748
FGFBP3 -9187 -6361
FGFR1 -8719 -822
FGFR2 -10068 -10229
FGFR4 -1760 -2742
FGFRL1 -10743 -8876
FLRT2 -2433 -3327
FLT1 3447 7527
FLT3 3904 8334
FLT3LG -415 -11122
FLT4 -5969 -7884
FOS 6663 6569
FOSB 339 1402
FOSL1 9842 8662
FRS2 1765 -3137
FRS3 8041 7694
FURIN 8111 10053
FYN -10878 -6729
GAB1 7926 5272
GAB2 7546 9347
GABRB3 -5615 199
GABRG2 5684 -1211
GALNT3 -9370 4339
GFAP 8363 6022
GGA3 509 5673
GRAP -5044 -10478
GRAP2 5425 4991
GRB10 10103 10040
GRB2 9631 9985
GTF2F1 -3109 7342
GTF2F2 4728 6017
HBEGF 5089 5189
HGF 9753 8929
HGS -381 6840
HNRNPA1 -2581 -3943
HNRNPF -334 5326
HNRNPH1 983 -9561
HNRNPM 2401 6565
HRAS -2248 -1932
HSP90AA1 5309 410
HSPB1 906 2714
ID1 -4474 7580
ID2 -11205 -1959
ID3 -8695 -7195
IGF1R 4264 6294
INSR 9014 8953
IRS1 6140 8
IRS2 8141 9618
ITCH -2889 3792
ITGA2 8852 -28
ITGA3 -6696 -9714
ITGAV 7467 6188
ITGB1 3360 -108
ITGB3 9450 8690
ITPR1 -5546 -5368
ITPR2 6833 6418
ITPR3 -8438 -9066
JAK2 7618 374
JUNB 5989 7459
JUND 69 2516
JUP -4305 -4960
KIDINS220 6851 7729
KIT -10872 -8011
KL 9145 9846
KRAS 3789 4070
LAMA1 1937 -1809
LAMA2 -10568 -6239
LAMA4 -5156 597
LAMA5 565 -2964
LAMB1 2797 7716
LAMB2 3126 -317
LAMB3 4293 8192
LAMC1 9628 10118
LAMC3 1290 -4227
LCK -10358 -10719
LRIG1 -3916 -10887
LYL1 8718 8646
LYN 7575 8379
MAP2K1 9163 9879
MAP2K2 185 8452
MAP2K5 3641 4561
MAPK1 1052 9260
MAPK11 7257 1843
MAPK12 1925 -1837
MAPK13 -8511 5595
MAPK14 9907 9606
MAPK3 8931 9626
MAPK7 -10125 5069
MAPKAP1 2536 5925
MAPKAPK2 -10572 6892
MAPKAPK3 7493 9250
MATK -11258 -9057
MEF2A 9000 8162
MEF2C 6943 -2868
MEF2D -9268 3542
MEMO1 9615 8983
MKNK1 8618 8672
MLST8 -3991 2978
MMP9 9225 9700
MST1 -4917 3393
MST1R -6825 -2819
MTOR -10419 -3248
MUC20 -2625 -6328
MXD4 -10907 -6100
NAB1 7194 -445
NAB2 -9246 -7768
NCBP1 1766 -6055
NCBP2 3719 -10143
NCF1 8576 7083
NCF2 9748 9694
NCF4 9697 9856
NCK1 -9250 -9113
NCK2 4176 5976
NCKAP1 6871 8168
NCKAP1L 3966 9566
NCOR1 3309 7790
NCSTN 9503 9869
NEDD4 -884 7132
NELFB -8446 5056
NOS3 5934 -5046
NRAS 7321 4878
NRG1 8713 914
NRG4 1196 -3291
NRP1 -9711 -5356
NRP2 -1597 -4081
NTRK1 -3499 -8157
PAG1 2942 5215
PAK1 9711 7682
PAK2 9019 8433
PAK3 -1134 -4249
PCSK5 6394 4664
PCSK6 9717 9061
PDE3B -7149 -10938
PDGFA 6115 5392
PDGFB -4645 -8897
PDGFC 1293 6752
PDGFD -11225 -8372
PDGFRA 2481 6753
PDGFRB -11134 -5992
PDPK1 2392 7816
PGF -8745 -1426
PIK3C3 6605 573
PIK3CA 6889 4182
PIK3CB 9838 9248
PIK3R1 -7197 -8942
PIK3R2 2459 5820
PIK3R3 -11107 -8159
PIK3R4 -267 -2209
PLAT 6118 -4882
PLCG1 -6360 -11043
PLG 1277 -2998
POLR2A -8726 2901
POLR2B -1034 188
POLR2C -2183 3527
POLR2D 3401 -4083
POLR2E 6766 8343
POLR2F -2307 6746
POLR2G -5778 6576
POLR2H 653 -2264
POLR2I -2123 2695
POLR2J 4448 7822
POLR2K 1881 -1885
POLR2L 126 7246
PPP2CA 8810 8328
PPP2CB 8482 7631
PPP2R1A -3087 6994
PPP2R1B 2503 437
PPP2R5D -6508 4985
PRKACA 9885 10068
PRKACB -9852 -10936
PRKCA 2473 1229
PRKCB 5395 8378
PRKCD 9393 9642
PRKCE -10383 -2720
PRKCZ -10855 -7708
PRR5 -11173 -8620
PSEN1 7889 8878
PSEN2 -5169 -5867
PSENEN 2692 7551
PTBP1 -3207 2729
PTK2 7786 3481
PTK2B 2270 9537
PTK6 6593 5974
PTPN1 -8327 7695
PTPN11 4691 6614
PTPN12 7921 9275
PTPN18 -1694 8540
PTPN2 7776 8909
PTPN3 -742 873
PTPN6 -691 7862
PTPRJ 4613 9148
PTPRK -5308 -7004
PTPRO 4554 2333
PTPRS -11226 -9306
PTPRU -4519 -979
PXN -5634 8031
RAB4A 9473 7027
RAB4B -7808 7089
RAC1 9052 9614
RALA 7124 1151
RALB 9150 8771
RALGDS -11080 -10024
RANBP10 2888 3405
RANBP9 3568 6133
RAP1A 8688 6973
RAP1B -2703 4941
RAPGEF1 -10851 -864
RASA1 4308 2428
RBFOX2 -7423 -5065
REST 534 1614
RHOA 8351 8888
RICTOR -3978 -9726
RIT1 9696 9723
RNF41 8699 9075
ROCK1 8315 7930
ROCK2 7628 6719
RPS27A -3555 -7070
RPS6KA1 -105 9153
RPS6KA2 -5428 3882
RPS6KA3 2859 3437
RPS6KA5 -3980 -11177
S100B -8212 -1271
SGK1 8717 2303
SH2B2 4083 9454
SH2B3 3129 4903
SH2D2A -11211 -10672
SH3GL1 4634 8807
SH3KBP1 4345 7311
SHB -4316 7281
SHC1 -3416 5815
SHC3 9229 -1001
SOCS1 -219 6051
SOCS6 8906 9207
SOS1 3534 -7412
SPARC 9073 7195
SPHK1 8030 8271
SPINT1 9479 8293
SPINT2 8182 8874
SPRED1 -7983 -6504
SPRED2 -404 8453
SPRY1 -6300 4904
SPRY2 -10148 1940
SRC -6857 -7229
SRF 4035 7760
STAM 3046 2017
STAM2 8115 5912
STAT1 -7385 -11118
STAT3 8512 8606
STAT5A 6437 7973
STAT5B 4758 7433
STAT6 2936 7753
STMN1 -6650 -7184
STUB1 -7516 3468
TAB2 9197 5726
TCF12 -1570 891
TCIRG1 1085 9058
TEC 8165 7953
TF 1794 1244
TGFA 7935 9686
THBS1 1778 8102
THBS3 8361 6974
THBS4 -5938 -7645
THEM4 -5349 -11202
TIA1 4573 -6920
TIAL1 5514 -4583
TIAM1 5732 -809
TLR9 -10413 -138
TNS3 9978 9419
TNS4 -6130 2655
TPH1 -2180 -9746
TRIB1 7599 8026
TRIB3 -7572 -1651
UBA52 -1875 3023
UBB 8251 6157
UBC -1915 5825
USP8 8542 6497
VAV1 5553 8731
VAV2 -5033 -1339
VAV3 -6160 7203
VEGFA 8464 8215
VEGFB -7685 -5963
VRK3 -7245 5798
WASF1 10091 10132
WASF2 7535 9576
WASF3 8142 7240
WWOX -10530 -7862
WWP1 813 -10536
YES1 -11138 -8566
YWHAB 8274 6101



Signaling by Interleukins

Signaling by Interleukins
metric value
setSize 385
pMANOVA 1.98e-21
p.adjustMANOVA 2.08e-19
s.dist 0.359
s.low.CRP 0.22
s.high.CRP 0.284
p.low.CRP 1.37e-13
p.high.CRP 1.03e-21




Top 20 genes
Gene low CRP high CRP
CSF2RA 10124 10140
S100A12 10088 10121
VAMP7 10053 10044
CCR2 10062 9973
TALDO1 10039 9995
PRKACA 9885 10068
SERPINB2 10012 9937
SOCS3 9830 10110
ITGAM 9846 10065
CD36 10064 9814
VIM 9794 10020
PTAFR 9791 9983
LMNB1 9994 9773
GRB2 9631 9985
IL17RA 9776 9824
DUSP3 9937 9647
IL1RN 10087 9470
IL10 9734 9799
FPR1 9606 9929
NKIRAS2 9581 9936

Click HERE to show all gene set members

All member genes
low CRP high CRP
AGER -1839.0 3181.0
AIP -8999.0 2061.0
AKT1 -4794.0 6231.0
ALOX15 -6345.0 -9981.0
ALOX5 9516.0 9496.0
ANXA1 8162.0 8222.0
ANXA2 8647.0 9102.0
APP 9951.0 9504.0
ARF1 8465.0 9910.0
ATF1 7833.0 5463.0
ATF2 7002.0 164.0
BATF 2430.0 7966.0
BCL2 6148.0 -7816.0
BCL2L1 9743.0 8443.0
BCL6 9554.0 9844.0
BIRC5 2725.0 4169.0
BLNK -5690.0 -5869.0
BOLA2 1674.0 2264.0
BRWD1 -2708.0 -9819.0
BTRC -6845.0 -441.0
CA1 10107.0 9363.0
CANX 6838.0 5751.0
CAPZA1 8666.0 8511.0
CASP1 8236.0 2513.0
CASP3 191.0 822.0
CBL 6620.0 8302.0
CCL2 -10976.0 -11174.0
CCL3 -407.0 -3940.0
CCL4 -11246.0 -6076.0
CCL5 -10668.0 -6900.0
CCND1 -4303.0 -5618.0
CCR1 9641.0 9012.0
CCR2 10062.0 9973.0
CCR5 -9863.0 -5213.0
CD36 10064.0 9814.0
CD4 3147.0 -5743.0
CD80 -2297.0 -7693.0
CD86 5511.0 -1419.0
CDC42 8498.0 7640.0
CDKN1A 3621.0 5190.0
CEBPD 8134.0 9779.0
CFL1 5851.0 9242.0
CHUK 9198.0 7663.0
CISH 9673.0 299.0
CLCF1 -10024.0 -9873.0
CNN2 2919.0 7385.0
CNTF 7371.0 3797.0
COL1A2 5690.0 684.0
CREB1 4878.0 -3476.0
CRK 9657.0 9429.0
CRKL 1263.0 5754.0
CRLF1 5043.0 -3947.0
CSF1 196.0 -1673.0
CSF1R -7485.0 3452.0
CSF2RA 10124.0 10140.0
CSF2RB 7899.0 7940.0
CSF3R 9184.0 9098.0
CTF1 -3543.0 6324.0
CTSG 9156.0 1689.0
CUL1 -2085.0 -10951.0
CXCL1 4484.0 5698.0
CXCL10 5012.0 -11168.0
CXCL2 6689.0 5198.0
CXCL8 3332.0 -907.0
DUSP3 9937.0 9647.0
DUSP4 -6630.0 -4192.0
DUSP6 7994.0 2589.0
DUSP7 -4748.0 387.0
EBI3 -8315.0 6258.0
ELK1 -355.0 3195.0
F13A1 9955.0 8516.0
FASLG -11268.0 -10430.0
FBXW11 4585.0 7364.0
FCER2 -951.0 -3382.0
FGF2 5967.0 3177.0
FN1 10003.0 6211.0
FOS 6663.0 6569.0
FOXO1 -4402.0 -9319.0
FOXO3 8202.0 9854.0
FPR1 9606.0 9929.0
FSCN1 8821.0 8081.0
FYN -10878.0 -6729.0
GAB2 7546.0 9347.0
GATA3 -10441.0 -11237.0
GRB2 9631.0 9985.0
GSTO1 9193.0 9858.0
H3C15 5262.5 7402.5
HAVCR2 -5218.0 8217.0
HCK 9286.0 9494.0
HGF 9753.0 8929.0
HIF1A 7330.0 7808.0
HMGB1 3876.0 -968.0
HMOX1 6942.0 9285.0
HNRNPA2B1 3618.0 4420.0
HNRNPDL -7295.0 -10631.0
HNRNPF -334.0 5326.0
HSP90AA1 5309.0 410.0
HSP90B1 7042.0 372.0
HSPA8 -8286.0 -8908.0
HSPA9 -3418.0 -7548.0
ICAM1 8336.0 6278.0
IFNG -9241.0 -7900.0
IFNLR1 -8009.0 -6857.0
IGHE -498.0 -5753.0
IGHG1 -1124.0 -7111.0
IGHG4 -4038.0 -5940.0
IKBKB -5276.0 -2118.0
IKBKG -3058.0 7903.0
IL10 9734.0 9799.0
IL10RA -10639.0 -5422.0
IL10RB 9501.0 9838.0
IL11RA -2776.0 -10746.0
IL12A 1034.0 -8967.0
IL12RB1 -10847.0 -9741.0
IL12RB2 -10883.0 -10308.0
IL13RA1 7666.0 4703.0
IL15 2367.0 -5668.0
IL15RA 4842.0 2414.0
IL16 -10494.0 -2458.0
IL17C -9039.0 -2080.0
IL17RA 9776.0 9824.0
IL17RB -3232.0 -5301.0
IL17RC -915.0 2324.0
IL17RE -3917.0 -4902.0
IL18 8340.0 7387.0
IL18BP -8737.0 -8962.0
IL18R1 -10880.0 5790.0
IL18RAP -11230.0 5060.0
IL19 5979.0 7746.0
IL1B 7489.0 3385.0
IL1R1 9455.0 9194.0
IL1R2 6574.0 9865.0
IL1RAP 3294.0 7375.0
IL1RL1 8858.0 -1567.0
IL1RN 10087.0 9470.0
IL20RB -5244.0 -8058.0
IL21R -11003.0 -10453.0
IL23A -695.0 -11027.0
IL24 -9185.0 -9782.0
IL27 5136.0 8604.0
IL27RA -88.0 4685.0
IL2RA 1007.0 -8826.0
IL2RB -11256.0 -10415.0
IL2RG -10931.0 -9531.0
IL31RA -3367.0 -6695.0
IL32 -8378.0 -9542.0
IL33 -438.0 931.0
IL3RA -10088.0 -10505.0
IL4 -7559.0 -9214.0
IL4R 5715.0 7951.0
IL5RA -8551.0 -10227.0
IL6R 9360.0 8189.0
IL6ST 7914.0 1855.0
IL7 -7208.0 -6964.0
IL7R -4956.0 -11140.0
IL9R -9017.0 -11233.0
INPP5D -10797.0 4515.0
INPPL1 9638.0 9488.0
IRAK1 2444.0 7601.0
IRAK2 -11058.0 -2404.0
IRAK3 9660.0 9553.0
IRF4 -202.0 -9788.0
IRS1 6140.0 8.0
IRS2 8141.0 9618.0
ITGAM 9846.0 10065.0
ITGAX 3250.0 8762.0
ITGB1 3360.0 -108.0
ITGB2 8042.0 10007.0
JAK1 -10669.0 -4353.0
JAK2 7618.0 374.0
JAK3 8703.0 8585.0
JUN 2838.0 4810.0
JUNB 5989.0 7459.0
LAMA5 565.0 -2964.0
LCK -10358.0 -10719.0
LCN2 9447.0 6200.0
LCP1 8415.0 8905.0
LGALS9 2565.0 3635.0
LMNB1 9994.0 9773.0
LYN 7575.0 8379.0
MAOA 9886.0 9426.0
MAP2K1 9163.0 9879.0
MAP2K3 8978.0 9308.0
MAP2K4 6895.0 7431.0
MAP2K6 9435.0 9577.0
MAP2K7 -2754.0 4813.0
MAP3K3 8280.0 9287.0
MAP3K7 1546.0 4274.0
MAP3K8 -7139.0 8928.0
MAPK1 1052.0 9260.0
MAPK10 6734.0 3872.0
MAPK11 7257.0 1843.0
MAPK14 9907.0 9606.0
MAPK3 8931.0 9626.0
MAPK7 -10125.0 5069.0
MAPK8 -1061.0 -9914.0
MAPK9 -6530.0 -1870.0
MAPKAPK2 -10572.0 6892.0
MAPKAPK3 7493.0 9250.0
MCL1 7723.0 7150.0
MEF2A 9000.0 8162.0
MEF2C 6943.0 -2868.0
MIF -4739.0 -1332.0
MMP1 9240.0 6657.0
MMP9 9225.0 9700.0
MSN -4366.0 7815.0
MTAP 3191.0 -6757.0
MUC1 8159.0 7011.0
MYC 8429.0 -2186.0
MYD88 8651.0 8344.0
NANOG 5462.0 317.0
NDN 3640.0 4458.0
NFKB1 7857.0 6377.0
NFKB2 3069.0 -1167.0
NFKBIA 6855.0 7374.0
NFKBIB -9679.0 5479.0
NKIRAS1 2619.0 689.0
NKIRAS2 9581.0 9936.0
NOD1 -10930.0 -10348.0
NOD2 9408.0 8613.0
OPRD1 -4129.0 -3347.0
OPRM1 4355.0 1404.0
OSM 7132.0 8038.0
OSMR -2892.0 -63.0
P4HB 6474.0 9641.0
PAK2 9019.0 8433.0
PDCD4 -7921.0 -11050.0
PELI1 9064.0 5690.0
PELI2 9242.0 9060.0
PELI3 5708.0 8764.0
PIK3CA 6889.0 4182.0
PIK3CB 9838.0 9248.0
PIK3CD 82.0 7288.0
PIK3R1 -7197.0 -8942.0
PIK3R2 2459.0 5820.0
PIK3R3 -11107.0 -8159.0
PIM1 9420.0 7031.0
PITPNA 6122.0 7384.0
POMC 1489.0 3391.0
POU2F1 -609.0 2898.0
PPIA -7248.0 -2108.0
PPP2CA 8810.0 8328.0
PPP2CB 8482.0 7631.0
PPP2R1A -3087.0 6994.0
PPP2R1B 2503.0 437.0
PPP2R5D -6508.0 4985.0
PRKACA 9885.0 10068.0
PRTN3 9645.0 4535.0
PSMA1 8278.0 7406.0
PSMA2 5830.0 5666.0
PSMA3 4646.0 -7621.0
PSMA4 3950.0 -1036.0
PSMA5 -2119.0 -3983.0
PSMA6 6893.0 5865.0
PSMA7 3550.0 8554.0
PSMB1 3915.0 4224.0
PSMB10 -7878.0 -1272.0
PSMB2 2664.0 4928.0
PSMB3 4971.0 8382.0
PSMB4 -3175.0 4911.0
PSMB5 6561.0 9138.0
PSMB6 1312.0 8784.0
PSMB7 8034.0 9051.0
PSMB8 -4481.0 75.0
PSMB9 -9105.0 -10433.0
PSMC1 6759.0 7782.0
PSMC2 -2524.0 4517.0
PSMC3 -4971.0 4984.0
PSMC4 -10757.0 -336.0
PSMC5 -3424.0 2764.0
PSMC6 8812.0 6000.0
PSMD1 7679.0 7587.0
PSMD10 2067.0 2450.0
PSMD11 6914.0 6824.0
PSMD12 9011.0 5710.0
PSMD13 3157.0 7205.0
PSMD14 2891.0 3041.0
PSMD2 4352.0 8396.0
PSMD3 -2243.0 6367.0
PSMD4 6858.0 9449.0
PSMD5 2770.0 4781.0
PSMD6 8841.0 8304.0
PSMD7 6534.0 6147.0
PSMD8 739.0 7117.0
PSMD9 3580.0 9001.0
PSME1 -7256.0 -7913.0
PSME2 -5548.0 -10355.0
PSME3 9120.0 8239.0
PSME4 -5205.0 -3127.0
PSMF1 6709.0 6770.0
PTAFR 9791.0 9983.0
PTGS2 6044.0 3823.0
PTK2B 2270.0 9537.0
PTPN11 4691.0 6614.0
PTPN12 7921.0 9275.0
PTPN13 -9422.0 -7282.0
PTPN14 444.0 -2588.0
PTPN18 -1694.0 8540.0
PTPN2 7776.0 8909.0
PTPN20 2731.0 -4226.0
PTPN23 -4984.0 2588.0
PTPN4 -10946.0 -10632.0
PTPN6 -691.0 7862.0
PTPN7 -10607.0 -6009.0
PTPN9 -2214.0 8622.0
RAG1 -10678.0 -8094.0
RALA 7124.0 1151.0
RAP1B -2703.0 4941.0
RAPGEF1 -10851.0 -864.0
RBX1 1418.0 4877.0
RELA -7305.0 2739.0
RHOU 7924.0 9743.0
RIPK2 1665.0 2297.0
RORA -10511.0 -10952.0
RORC -6496.0 -10569.0
RPLP0 3127.0 -1531.0
RPS27A -3555.0 -7070.0
RPS6KA1 -105.0 9153.0
RPS6KA2 -5428.0 3882.0
RPS6KA3 2859.0 3437.0
RPS6KA5 -3980.0 -11177.0
S100A12 10088.0 10121.0
S100B -8212.0 -1271.0
S1PR1 -10750.0 -4787.0
SEM1 993.0 5942.0
SERPINB2 10012.0 9937.0
SHC1 -3416.0 5815.0
SIGIRR -9900.0 -8613.0
SKP1 8120.0 2700.0
SMAD3 -10084.0 -10081.0
SMARCA4 -2731.0 7803.0
SNRPA1 -7002.0 -9934.0
SOCS1 -219.0 6051.0
SOCS2 4901.0 -4080.0
SOCS3 9830.0 10110.0
SOCS5 6009.0 2808.0
SOD1 -1389.0 -3334.0
SOD2 4529.0 4854.0
SOS1 3534.0 -7412.0
SOS2 9141.0 8628.0
SQSTM1 4693.0 4549.0
STAT1 -7385.0 -11118.0
STAT2 -5116.0 -9909.0
STAT3 8512.0 8606.0
STAT4 -11142.0 -11112.0
STAT5A 6437.0 7973.0
STAT5B 4758.0 7433.0
STAT6 2936.0 7753.0
STX1A -9454.0 1322.0
STX3 9343.0 8695.0
STX4 -7285.0 5736.0
STXBP2 9017.0 9835.0
SYK 9464.0 9848.0
TAB1 6623.0 5746.0
TAB2 9197.0 5726.0
TAB3 3912.0 3647.0
TALDO1 10039.0 9995.0
TBK1 5846.0 2973.0
TCP1 7677.0 2853.0
TEC 8165.0 7953.0
TGFB1 -2566.0 6745.0
TIMP1 6136.0 9944.0
TNF -3598.0 -6316.0
TNFRSF1A 9563.0 9913.0
TNFRSF1B 1146.0 8282.0
TNIP2 -1490.0 7359.0
TOLLIP 8447.0 9165.0
TP53 -7284.0 -8934.0
TRAF6 -1767.0 2089.0
TXLNA 1637.0 -298.0
TYK2 4430.0 8605.0
UBA52 -1875.0 3023.0
UBB 8251.0 6157.0
UBC -1915.0 5825.0
UBE2N 4087.0 2050.0
UBE2V1 6665.0 5995.0
VAMP2 -9677.0 -10779.0
VAMP7 10053.0 10044.0
VAV1 5553.0 8731.0
VEGFA 8464.0 8215.0
VIM 9794.0 10020.0
VRK3 -7245.0 5798.0
YES1 -11138.0 -8566.0
YWHAZ 5165.0 5861.0
ZEB1 -2926.0 -6551.0



Metabolism of lipids

Metabolism of lipids
metric value
setSize 619
pMANOVA 2.02e-20
p.adjustMANOVA 1.97e-18
s.dist 0.249
s.low.CRP 0.113
s.high.CRP 0.222
p.low.CRP 1.62e-06
p.high.CRP 3.83e-21




Top 20 genes
Gene low CRP high CRP
PLBD1 10121 10138
PPARG 10111 10137
CTSA 10083 10131
PLB1 9997 10127
CYP1B1 9899 10133
HADHB 10016 9979
PLIN3 9856 10099
PRKACA 9885 10068
HSD3B7 9875 10077
CD36 10064 9814
PLD1 9826 9945
PCTP 9909 9764
TSPO 9681 9965
PLA2G4A 9622 10024
SGMS2 9876 9677
GPX1 9948 9589
SBF2 9757 9727
LTA4H 9933 9541
FIG4 9442 9960
ACSL1 9679 9692

Click HERE to show all gene set members

All member genes
low CRP high CRP
AACS -33 2141
ABCA1 5566 7323
ABCB4 -1968 -4715
ABCC1 686 2817
ABCC3 5573 6872
ABCD1 6353 8582
ABHD3 8545 6951
ABHD4 1373 8133
ABHD5 8602 8289
ACAA1 6662 9280
ACAA2 -1985 5348
ACACA 2977 6128
ACACB -6144 -9025
ACAD10 6343 5354
ACAD11 -5270 -10034
ACADL -1862 401
ACADM 7350 -3486
ACADS -4002 6806
ACADVL 8805 8687
ACAT1 8245 4817
ACAT2 3136 -2924
ACBD4 -905 -3679
ACBD5 -7062 2964
ACBD6 -10077 -8638
ACBD7 5590 2323
ACER1 -1818 -8868
ACER2 5652 616
ACER3 9987 9382
ACLY -3163 7024
ACOT1 -7451 -1398
ACOT11 -4357 1862
ACOT13 6638 5659
ACOT2 -10662 -4993
ACOT4 -9703 -8244
ACOT7 -7000 678
ACOT8 6370 8924
ACOT9 4296 6690
ACOX1 9598 9253
ACOX2 8876 10071
ACOX3 1446 7517
ACOXL 6296 4342
ACP6 -4193 -2114
ACSBG1 -3996 1079
ACSF2 -10503 -8147
ACSF3 -2418 2062
ACSL1 9679 9692
ACSL3 8319 8132
ACSL4 9543 9115
ACSL5 -9738 -6853
ACSL6 5399 -8643
ACSM3 -857 -6921
ACSM6 -700 5531
ACSS3 8598 9213
AGK -9841 -11206
AGPAT1 7745 9088
AGPAT2 9161 10022
AGPAT3 6352 4771
AGPAT4 -10357 -2707
AGPAT5 -1021 -9192
AGPS 8149 4749
AHR 9187 6903
AHRR -7879 -1783
AKR1B1 -10733 -10509
AKR1B15 7018 1575
AKR1C1 6158 -2806
AKR1C2 1132 -7880
AKR1C3 -11152 -8047
ALAS1 8849 7669
ALB 1254 3551
ALDH3A2 6046 457
ALDH3B1 8834 9423
ALOX12 8526 7700
ALOX12B -5522 -6022
ALOX15 -6345 -9981
ALOX15B 9448 7656
ALOX5 9516 9496
ALOX5AP 4064 8312
AMACR -10395 -976
ANGPTL4 -7923 824
APOA2 2715 7325
ARF1 8465 9910
ARF3 5651 9049
ARNT 7974 9384
ARNTL -10595 821
ARSA -218 5556
ARSB 8124 8067
ARSD 8118 8210
ARSG -5202 -1774
ARSJ -1176 -6399
ARSK -8263 -10357
ARV1 -1109 -1377
ASAH1 9274 8880
ASAH2 -7550 -7763
B3GALNT1 1825 6391
BDH1 -4059 -10697
BDH2 -8089 -10646
BMX 6882 9193
CARM1 9361 9442
CAV1 2492 1598
CBR1 1382 2892
CBR4 961 -557
CCNC 7860 -2135
CD36 10064 9814
CDIPT 2094 7603
CDK19 6602 9278
CDK8 -3688 1375
CDS1 -529 -2994
CDS2 4323 8193
CEPT1 5983 -21
CERK -9345 843
CERS2 9130 9519
CERS3 2778 -4286
CERS4 -8028 -2091
CERS5 -7630 2065
CERS6 7455 5780
CERT1 9201 7883
CHD9 -4184 -2634
CHKA 5698 6720
CHKB -3896 -1236
CHPT1 9431 9184
CLOCK -568 -7717
CPNE1 -7895 1521
CPNE3 7732 5446
CPNE7 -5324 -5968
CPT1A 2381 6786
CPT1B -3067 -4000
CPT2 4442 8015
CPTP -2928 5586
CRAT 9280 9619
CREBBP -4951 6023
CRLS1 9938 8963
CROT -9474 -10996
CSNK1G2 -8130 4845
CSNK2A1 3192 8248
CSNK2A2 6050 7886
CSNK2B 1222 5287
CTSA 10083 10131
CUBN -446 -9567
CYP1A2 -3599 1804
CYP1B1 9899 10133
CYP27A1 5365 3927
CYP2C9 -1455 5957
CYP2D6 -5583 -8281
CYP2E1 -7402 -10555
CYP2R1 -9982 -6118
CYP2U1 -10449 -10397
CYP46A1 3429 -1761
CYP4F22 -11214 -10272
CYP4F3 5306 6371
CYP4F8 -3981 186
CYP51A1 7585 6990
CYP7B1 -4766 -2364
DBI -1941 8632
DDHD1 -7729 -11016
DDHD2 -8127 -11095
DECR1 6381 5874
DECR2 -34 2009
DEGS1 6718 6254
DEGS2 -10766 -7572
DGAT1 3473 6135
DGAT2 9319 9775
DHCR24 -6328 4423
DHCR7 1111 7390
DHRS7B 6356 8607
DPEP2 -4986 -926
DPEP3 -4594 -1297
EBP -10781 -9206
ECHS1 1217 -1164
ECI1 -39 1998
ECI2 -9181 -10495
EHHADH 6611 6676
ELOVL1 2831 8404
ELOVL3 9817 8219
ELOVL4 -1358 -9048
ELOVL5 6808 6251
ELOVL6 -11059 -5972
ELOVL7 9219 7532
ENPP6 -972 727
EP300 4311 7552
EPHX2 -1489 -11090
ESRRA 740 8079
ESYT1 -10789 -10656
ESYT2 -10180 -9316
ETNK1 5034 -2684
ETNK2 -9067 -6126
FA2H 713 -4597
FAAH -2227 -5779
FAAH2 5259 -9362
FABP2 -2791 5054
FABP3 -8776 -7846
FABP5 4135 6969
FADS1 7716 8547
FADS2 -5372 3556
FAM120B -1528 3105
FAR1 9850 8567
FAR2 10026 8691
FASN -3242 1451
FDFT1 4112 8461
FDPS -1169 7584
FDX1 5786 1343
FDX2 -4897 -2162
FDXR 8050 3941
FHL2 3293 4988
FIG4 9442 9960
FITM1 -6458 -3216
FITM2 2033 -6705
G0S2 3165 1605
GALC 7644 9719
GBA 8941 9735
GBA2 -5705 6458
GDE1 9232 8896
GDPD1 -7013 -524
GDPD3 6200 6580
GDPD5 -9141 -9606
GGPS1 5672 -3243
GGT1 8068 10073
GGT5 -6888 1713
GK 9560 9415
GLA 8923 9083
GLB1 9091 9091
GLB1L 4424 2509
GLIPR1 9841 6015
GLTP 6336 9890
GM2A 9396 9808
GNPAT 8372 6492
GPAM -4790 -9067
GPAT2 -4992 -3853
GPAT3 8990 8251
GPAT4 -7656 7009
GPCPD1 9553 8702
GPD1 -6288 -5099
GPD1L -7900 -8240
GPD2 8788 7751
GPS2 -6562 2341
GPX1 9948 9589
GPX2 -4296 -1665
GPX4 3416 5814
GRHL1 -520 903
GSTM4 1189 1508
HACD1 6205 4226
HACD2 3078 -2009
HACD3 -5333 -9766
HACD4 8287 6869
HACL1 -7200 -10652
HADH -8975 -10276
HADHA 8951 9801
HADHB 10016 9979
HDAC3 1719 6319
HELZ2 -10464 -4663
HEXA 1650 2356
HEXB 9386 9202
HILPDA 4029 -2557
HMGCL -183 7666
HMGCR 8736 8314
HMGCS1 -1269 -202
HPGD 5710 7919
HSD11B2 3975 4314
HSD17B1 6487 3122
HSD17B11 9269 7792
HSD17B12 8715 6838
HSD17B13 5139 5393
HSD17B2 207 4487
HSD17B4 9821 8748
HSD17B7 -2996 -10046
HSD17B8 -8758 -9338
HSD3B7 9875 10077
HTD2 4062 1001
IDI1 7412 7340
INPP4A -10541 -2748
INPP4B 2225 -11160
INPP5D -10797 4515
INPP5E -2606 -9106
INPP5F -4077 -3372
INPP5K -7690 2475
INPPL1 9638 9488
INSIG1 -10932 -4568
INSIG2 7642 6198
KDSR 5554 -8807
KPNB1 -1223 3575
LBR 8953 8145
LCLAT1 2876 -770
LGMN -3548 -2820
LIPE -6752 -7655
LIPH -806 5104
LPCAT1 -10952 2487
LPCAT2 9661 8661
LPCAT3 8263 9435
LPCAT4 -6623 -6856
LPGAT1 9154 8941
LPIN1 -9710 -9564
LPIN2 -2883 -5257
LPIN3 2760 -7145
LRP2 964 1845
LSS -10074 -7255
LTA4H 9933 9541
LTC4S -7039 2930
MAPKAPK2 -10572 6892
MBOAT1 6932 5567
MBOAT2 9585 8220
MBOAT7 8301 9221
MBTPS1 1704 4208
MBTPS2 2221 584
MCAT 3071 6616
MCEE -318 -4292
ME1 9337 9516
MECR -5607 -5047
MED1 -2730 -1762
MED10 -5268 -7090
MED11 -5849 3435
MED12 -6426 4924
MED13 3230 3171
MED13L 5428 7259
MED14 -1391 1994
MED15 -9816 -5112
MED16 1626 7040
MED17 6659 2906
MED18 -3248 7029
MED19 4205 3722
MED20 4514 8084
MED21 2129 -7223
MED22 -1721 5575
MED23 -4613 -4897
MED24 -9186 -918
MED25 4853 7553
MED26 -5273 7174
MED27 -10124 -2305
MED28 2447 -1143
MED29 -9108 -967
MED30 -7460 -966
MED31 7152 -877
MED4 5576 3120
MED6 5195 -1751
MED7 1493 1153
MED8 7164 8014
MED9 -9724 -1868
MFSD2A 3282 -3810
MGLL 8873 7773
MID1IP1 2483 4553
MIGA1 4402 -9507
MIGA2 -7400 -1345
MLYCD -8982 -5715
MMAA -7883 -9948
MMUT 5151 3819
MOGAT3 -5876 663
MORC2 -4157 -8774
MSMO1 3451 2480
MTF1 9635 9358
MTM1 9605 4142
MTMR1 -8862 357
MTMR10 8590 8475
MTMR12 -6255 2780
MTMR14 7743 8920
MTMR2 2 -1144
MTMR3 9216 9859
MTMR4 -1239 4307
MTMR6 8965 7813
MTMR7 -1669 -2653
MTMR8 -8236 -7927
MTMR9 4316 1779
MVD -10176 2670
MVK -10455 -1828
NCOA1 -1753 6268
NCOA2 -4443 3788
NCOA3 3630 4256
NCOA6 1381 7728
NCOR1 3309 7790
NCOR2 4843 9646
NDUFAB1 7789 5216
NEU1 9336 9571
NEU3 -1390 -1896
NFYA 3506 4239
NFYB -726 -10664
NFYC 6238 8722
NPAS2 3422 -335
NR1D1 -5157 -8776
NR1H2 4003 8448
NR1H3 -8939 2196
NRF1 -10463 -30
NSDHL 897 5839
NUDT19 5969 7625
NUDT7 3319 956
OCRL 7540 6631
ORMDL1 -647 -5722
ORMDL2 -1137 7315
ORMDL3 -9307 -7231
OSBP -4943 1320
OSBPL10 764 -3626
OSBPL1A -7890 -3076
OSBPL2 -9184 6634
OSBPL3 -10108 -10957
OSBPL5 -11168 -8140
OSBPL6 7361 3374
OSBPL7 -9913 -10464
OSBPL8 8564 6575
OSBPL9 6176 6694
OXCT1 -8779 -10705
OXCT2 173 -2803
PCCA -5749 -6966
PCCB -7266 -3557
PCTP 9909 9764
PCYT1A 4565 7128
PCYT1B 8218 8793
PCYT2 -10691 -6884
PECR 9763 9101
PEMT 6341 2345
PEX11A -10460 -2960
PGS1 9084 9373
PHOSPHO1 -3118 4072
PHYH 1932 -3057
PI4K2A -10792 2983
PI4K2B -7633 -10842
PI4KA -7058 2288
PI4KB -6243 778
PIAS4 -1432 8309
PIK3C2A 1258 -5821
PIK3C2B -9423 -10059
PIK3C2G 692 2494
PIK3C3 6605 573
PIK3CA 6889 4182
PIK3CB 9838 9248
PIK3CD 82 7288
PIK3CG -9742 5545
PIK3R1 -7197 -8942
PIK3R2 2459 5820
PIK3R3 -11107 -8159
PIK3R4 -267 -2209
PIK3R5 -9700 3911
PIK3R6 8267 7206
PIKFYVE 4628 3510
PIP4K2A -8599 2837
PIP4K2B -7642 -3179
PIP4K2C -10764 -5694
PIP5K1A 6224 6407
PIP5K1B 5094 7192
PIP5K1C -4447 6435
PISD 9461 9362
PITPNB 14 -5378
PITPNM1 -3031 7875
PITPNM2 -6691 -2278
PITPNM3 -3701 -2129
PLA2G10 996 -4331
PLA2G12A 8347 5019
PLA2G15 8284 9631
PLA2G2D -3039 -4555
PLA2G4A 9622 10024
PLA2G4B -1937 -7077
PLA2G4C -1895 -3087
PLA2G4D 2605 422
PLA2G6 -10753 -10993
PLA2R1 2526 3806
PLAAT1 7523 6061
PLAAT2 4649 -1451
PLAAT3 -10520 -2397
PLAAT4 -10969 -11040
PLB1 9997 10127
PLBD1 10121 10138
PLD1 9826 9945
PLD2 7087 7779
PLD3 8640 7098
PLD4 -11266 -11216
PLD6 3638 -7258
PLEKHA1 -10730 -11019
PLEKHA2 -5997 2173
PLEKHA3 -5088 -1720
PLEKHA4 -1073 2011
PLEKHA5 -5362 -2954
PLEKHA6 -2691 -787
PLEKHA8 2578 -3278
PLIN1 -6629 -678
PLIN2 6368 9669
PLIN3 9856 10099
PLPP1 6735 -9356
PLPP2 5168 193
PLPP3 6276 9462
PLPP6 -9831 -6651
PMVK -1803 5434
PNPLA2 9239 9613
PNPLA4 -5903 430
PNPLA6 -1244 8600
PNPLA7 -1935 -7059
PNPLA8 9265 7482
POMC 1489 3391
PON2 -4434 -4773
PPARA -791 2682
PPARD -2381 -5446
PPARG 10111 10137
PPARGC1A 7923 1692
PPARGC1B -2475 -4269
PPM1L -9625 3554
PPP1CA -5695 6595
PPP1CB 8657 6666
PPP1CC 9200 4868
PPT1 9946 8681
PPT2 -10048 -9076
PRKAB2 -3794 -7488
PRKACA 9885 10068
PRKACB -9852 -10936
PRKAG2 7892 7
PRKD2 -10545 -3285
PRKD3 1523 2383
PRXL2B 728 -6849
PSAP 7519 7770
PTDSS1 8097 6669
PTDSS2 6491 6099
PTEN 9191 8752
PTGDS -10836 -6070
PTGES -5184 6141
PTGES2 -6197 -3780
PTGES3 8385 2175
PTGR1 9237 9969
PTGR2 2097 1589
PTGS1 9559 8597
PTGS2 6044 3823
PTPMT1 2320 2876
PTPN13 -9422 -7282
RAB14 8215 7014
RAB4A 9473 7027
RAB5A 8478 6815
RAN -2391 -4763
RGL1 7936 8025
RORA -10511 -10952
RUFY1 6901 6963
RXRA 6327 8932
RXRB -7622 2709
SACM1L -8224 -5336
SAMD8 9137 7361
SAR1B 8795 5984
SBF1 -10462 -5210
SBF2 9757 9727
SC5D 3897 -4878
SCAP -6407 344
SCD 6578 3616
SCD5 -10066 -2380
SCP2 6933 4053
SEC23A 8776 6905
SEC24A 8318 7788
SEC24B 1663 5398
SEC24C -9662 3561
SEC24D 8017 8795
SELENOI -4666 -10648
SGMS1 9171 9489
SGMS2 9876 9677
SGPL1 -5878 6696
SGPP1 -11051 -9436
SGPP2 -4526 -8818
SIN3A -9037 -7770
SIN3B -4559 -1682
SLC10A1 4523 -3989
SLC22A5 8129 6640
SLC25A1 -843 6264
SLC25A17 -7117 -9512
SLC25A20 -6402 7153
SLC27A1 9371 8373
SLC27A2 6501 -6385
SLC27A3 -3668 1756
SLC27A5 -5914 -8
SLC44A1 9313 9124
SLC44A2 -8609 5338
SLC44A5 -358 -4399
SMARCD3 9870 8230
SMPD1 -9838 5204
SMPD2 -7187 6202
SMPD3 -11070 -10458
SMPD4 -10327 -8352
SP1 8282 9168
SPHK1 8030 8271
SPHK2 -5524 6361
SPNS2 5814 5993
SPTLC1 9241 8962
SPTLC2 9108 9317
SPTLC3 3877 675
SPTSSA 7995 3610
SPTSSB -10164 -4445
SQLE -2471 5367
SRD5A1 9492 7352
SRD5A3 3417 4347
SREBF1 8758 5979
SREBF2 5424 7541
STAR -3804 76
STARD10 5224 5133
STARD3 -7867 7146
STARD3NL 6126 8112
STARD4 -448 -3799
STARD5 -10081 3667
STARD7 5361 4192
STS 1348 5281
SUMF1 9162 9651
SUMF2 -10998 -8612
SUMO2 6089 5153
SYNJ1 5518 6949
SYNJ2 -6592 -7005
TAZ 406 5258
TBL1X 8359 8499
TBL1XR1 4714 4779
TBXAS1 9105 9461
TECR -8480 -6099
TECRL -2441 2970
TGS1 -141 -4762
THEM4 -5349 -11202
THEM5 -6790 -7616
THRAP3 -3609 3263
TIAM2 -10122 -8001
TM7SF2 -7355 -4373
TMEM86B 1635 4473
TNFAIP8 4860 -1256
TNFAIP8L1 -9011 -7251
TNFAIP8L2 4641 6495
TNFRSF21 -11248 -7530
TRIB3 -7572 -1651
TSPO 9681 9965
TSPOAP1 -10988 -7555
TXNRD1 8327 8699
UBE2I -4201 2754
UGCG 2716 5849
UGT8 -3604 -4150
VAC14 -6990 4152
VAPA 9732 9322
VAPB 5092 2395
VDR 7908 9387



Disease

Disease
metric value
setSize 1339
pMANOVA 2.21e-19
p.adjustMANOVA 2.01e-17
s.dist 0.179
s.low.CRP 0.0971
s.high.CRP 0.151
p.low.CRP 2.52e-09
p.high.CRP 1.99e-20




Top 20 genes
Gene low CRP high CRP
CSF2RA 10124 10140
ADAMTS2 10123 10126
FZD5 10104 10128
WASF1 10091 10132
IDH1 10122 10092
CTSA 10083 10131
VCAN 10068 10125
F12 10075 10096
HRH2 10051 10037
CD163 10038 10038
TALDO1 10039 9995
CYP1B1 9899 10133
OPLAH 10032 9930
PRKACA 9885 10068
CD36 10064 9814
LMNB1 9994 9773
IMPDH1 9819 9891
GNG10 9939 9753
GNS 9627 10060
CYFIP1 9724 9912

Click HERE to show all gene set members

All member genes
low CRP high CRP
AAAS -8564.0 -4273.0
ABCA1 5566.0 7323.0
ABCA3 -10824.0 -8696.0
ABCB4 -1968.0 -4715.0
ABCB6 8402.0 6175.0
ABCC2 -1995.0 -911.0
ABCC6 8075.0 4650.0
ABCC9 -7760.0 -1242.0
ABCD1 6353.0 8582.0
ABCD4 -7007.0 -5916.0
ABCG8 4588.0 3009.0
ABI1 6692.0 7709.0
ABI2 -7512.0 -9823.0
ABL1 -6354.0 4467.0
ACACA 2977.0 6128.0
ACTB 9310.0 9714.0
ACTG1 7674.0 9499.0
ACTR2 8743.0 7962.0
ACTR3 8622.0 7832.0
ACY1 -1118.0 -3475.0
ADAM10 9314.0 9481.0
ADAM17 8058.0 9718.0
ADAMTS1 -11098.0 -5754.0
ADAMTS10 -10752.0 -8150.0
ADAMTS13 -3300.0 -3397.0
ADAMTS14 -10382.0 -1142.0
ADAMTS16 -5113.0 -7987.0
ADAMTS17 1930.0 -5706.0
ADAMTS2 10123.0 10126.0
ADAMTS4 -10045.0 -8251.0
ADAMTS5 4721.0 -5392.0
ADAMTS6 -6097.0 -5389.0
ADAMTSL3 2431.0 443.0
ADAMTSL4 7713.0 8020.0
ADAMTSL5 462.0 -10240.0
ADCY2 -4785.0 -910.0
ADCY3 8645.0 9780.0
ADCY4 4042.0 6126.0
ADCY5 -8988.0 -4426.0
ADCY6 -4846.0 651.0
ADCY7 -8603.0 2306.0
ADCY9 -3025.0 2535.0
ADM 8460.0 10101.0
ADM2 9195.0 4133.0
ADORA2A -4195.0 4298.0
ADORA2B 8620.0 9622.0
ADRB1 -9979.0 -3157.0
ADRB2 -11122.0 -7027.0
AGGF1 6052.0 6971.0
AGK -9841.0 -11206.0
AGRN -9794.0 -10649.0
AGTRAP 9096.0 9556.0
AHCY -3099.0 3265.0
AHCYL1 6114.0 7566.0
AKAP9 2530.0 -6270.0
AKT1 -4794.0 6231.0
AKT1S1 8045.0 8241.0
AKT2 -8391.0 5504.0
AKT3 -9616.0 -10833.0
ALDOB -5354.0 82.0
ALG1 -9753.0 -1781.0
ALG11 -3019.0 -1403.0
ALG12 -787.0 4333.0
ALG13 -1043.0 -8422.0
ALG14 7527.0 5733.0
ALG2 3111.0 -119.0
ALG3 2590.0 -813.0
ALG6 5735.0 527.0
ALG8 4756.0 -5192.0
ALG9 -6685.0 -8829.0
AMER1 -9251.0 -9464.0
AMN 2539.0 -5736.0
ANAPC1 -9718.0 -10978.0
ANAPC10 -4639.0 -2175.0
ANAPC11 3528.0 7783.0
ANAPC15 9024.0 9609.0
ANAPC16 2266.0 -1817.0
ANAPC2 -6824.0 -4561.0
ANAPC4 1210.0 -8491.0
ANAPC5 -8996.0 -8730.0
ANAPC7 -4282.0 -1578.0
ANTXR2 7254.0 7992.0
AP1B1 8214.0 9804.0
AP1G1 -1796.0 5288.0
AP1M1 -3219.0 8558.0
AP1M2 4764.0 1487.0
AP1S1 9235.0 9982.0
AP1S2 6862.0 -6065.0
AP1S3 -5309.0 -4187.0
AP2A1 -3194.0 9104.0
AP2A2 3196.0 9217.0
AP2B1 -9145.0 2444.0
AP2M1 7742.0 9334.0
AP2S1 7422.0 8877.0
AP3B1 8649.0 9145.0
APBB1IP 9427.0 9201.0
APC 3083.0 3959.0
APH1A -3379.0 6321.0
APH1B 6306.0 6678.0
APOBEC3G -10981.0 -8824.0
APP 9951.0 9504.0
ARAF -5280.0 5379.0
AREG 4465.0 7165.0
ARF1 8465.0 9910.0
ARID4A 6304.0 2957.0
ARID4B -93.0 379.0
ARPC1A 8875.0 9605.0
ARPC1B 9259.0 10026.0
ARPC2 5327.0 8212.0
ARPC3 8430.0 8946.0
ARPC4 4637.0 8915.0
ARPC5 9301.0 9174.0
ARRB1 -4581.0 4541.0
ARRB2 7827.0 9274.0
ARSB 8124.0 8067.0
ATG7 9062.0 8455.0
ATP1A1 -1628.0 4842.0
ATP1A3 -10997.0 -7709.0
ATP1A4 -752.0 1945.0
ATP1B1 -8715.0 -6224.0
ATP1B2 7770.0 5919.0
ATP1B3 -6365.0 2479.0
ATP6V1H 7942.0 8571.0
AVPR1A 4473.0 3102.0
AVPR2 1919.0 -154.0
AXIN1 -10901.0 -2157.0
B2M -4257.0 -4660.0
B3GALT6 -6286.0 -359.0
B3GAT3 -7211.0 2864.0
B3GLCT -10606.0 -8784.0
B4GALT1 -4177.0 7099.0
B4GALT7 -4388.0 -6269.0
B4GAT1 -4385.0 -4229.0
BAD 1009.0 8765.0
BAG4 9013.0 9084.0
BAIAP2 2620.0 -682.0
BANF1 -5981.0 -803.0
BCL2L11 8059.0 7998.0
BCR -10286.0 261.0
BECN1 6040.0 6760.0
BIN2 -7555.0 7878.0
BRAF 276.0 2552.0
BRAP 7133.0 5359.0
BRD4 1769.0 8436.0
BRK1 5522.0 8298.0
BRMS1 -761.0 7440.0
BSG 9373.0 9841.0
BTD -10400.0 -10724.0
BTK 7623.0 7870.0
BTRC -6845.0 -441.0
C1GALT1 1726.0 -3586.0
C1GALT1C1 8882.0 8311.0
C1QBP 3448.0 -906.0
C3 -11179.0 -10489.0
C3AR1 8924.0 8181.0
CALCRL 8032.0 3879.0
CALM1 -6645.0 1321.0
CALR 6685.0 6374.0
CAMK2D -9328.0 -10857.0
CAMK2G -646.0 3153.0
CAMK4 246.0 -11195.0
CANX 6838.0 5751.0
CAPN1 7094.0 9770.0
CAPN2 -829.0 2369.0
CAPNS1 5468.0 8812.0
CASP1 8236.0 2513.0
CASP8 -10359.0 -8523.0
CASP9 5303.0 9133.0
CAST 8617.0 8824.0
CBL 6620.0 8302.0
CBLL1 -6075.0 -6513.0
CBX1 4880.0 5492.0
CCNC 7860.0 -2135.0
CCND1 -4303.0 -5618.0
CCND2 -9485.0 -10588.0
CCND3 -1611.0 8856.0
CCNE1 -8303.0 -11081.0
CCNE2 6498.0 5473.0
CCNH 4815.0 497.0
CCNK -3547.0 4337.0
CCNT1 -8231.0 -6368.0
CCNT2 770.0 -5045.0
CCR5 -9863.0 -5213.0
CD14 9551.0 9658.0
CD163 10038.0 10038.0
CD19 -2992.0 -2929.0
CD247 -11271.0 -10327.0
CD28 -2082.0 -11208.0
CD320 -9568.0 -7192.0
CD36 10064.0 9814.0
CD3G -9054.0 -10504.0
CD4 3147.0 -5743.0
CD80 -2297.0 -7693.0
CD86 5511.0 -1419.0
CD8B -1890.0 -9880.0
CD9 9005.0 4476.0
CDC16 -858.0 -5118.0
CDC23 -7178.0 -9273.0
CDC25A 3970.0 2814.0
CDC25B -10025.0 -11135.0
CDC26 3465.0 3689.0
CDC27 1988.0 -5.0
CDC37 -4604.0 7006.0
CDC42 8498.0 7640.0
CDH1 -10697.0 -8067.0
CDK2 -5388.0 -2127.0
CDK4 -9596.0 -8845.0
CDK5 8395.0 9380.0
CDK5R1 -8396.0 3375.0
CDK6 2472.0 -7898.0
CDK7 6075.0 5416.0
CDK8 -3688.0 1375.0
CDK9 -10657.0 5444.0
CDKN1A 3621.0 5190.0
CDKN1B -9926.0 -2672.0
CDKN1C -11201.0 -7265.0
CDKN2A -3659.0 -3958.0
CEBPD 8134.0 9779.0
CFP 6744.0 8615.0
CHD3 -9446.0 -6383.0
CHD4 -8254.0 587.0
CHMP1A -1421.0 7595.0
CHMP2A 8348.0 9510.0
CHMP2B 7436.0 5296.0
CHMP3 8980.0 8782.0
CHMP4A -1130.0 4862.0
CHMP4B 8338.0 9679.0
CHMP5 5879.0 5138.0
CHMP6 -6653.0 8292.0
CHMP7 -4593.0 -8038.0
CHST14 -8319.0 4910.0
CHST6 -784.0 -5074.0
CHSY1 9045.0 8148.0
CHUK 9198.0 7663.0
CLCN6 4520.0 2014.0
CLTA 8416.0 8998.0
CLTC 9376.0 9720.0
CNKSR1 2877.0 -8713.0
CNKSR2 786.0 -5158.0
CNTRL 120.0 -7228.0
COMT 8187.0 8862.0
CORO1A -5520.0 7058.0
CP -4947.0 388.0
CPSF4 -9344.0 -4421.0
CPSF6 4443.0 -8013.0
CRBN 1035.0 -5173.0
CREB1 4878.0 -3476.0
CREBBP -4951.0 6023.0
CRHR2 -7107.0 -2145.0
CRK 9657.0 9429.0
CSF2RA 10124.0 10140.0
CSF2RB 7899.0 7940.0
CSK -5436.0 7707.0
CSNK1A1 8062.0 8483.0
CSPG4 -5789.0 -2201.0
CTBP1 -10319.0 2597.0
CTBP2 -8332.0 7583.0
CTDP1 -5483.0 8151.0
CTNNB1 3201.0 7613.0
CTNND1 -4159.0 -7796.0
CTSA 10083.0 10131.0
CTSG 9156.0 1689.0
CTSL -5538.0 5895.0
CUBN -446.0 -9567.0
CUL1 -2085.0 -10951.0
CUL5 7502.0 -2980.0
CUX1 8954.0 9964.0
CXCR4 -3561.0 1966.0
CYBA -48.0 8901.0
CYFIP1 9724.0 9912.0
CYFIP2 -10558.0 -4935.0
CYP1B1 9899.0 10133.0
CYP27A1 5365.0 3927.0
CYP2R1 -9982.0 -6118.0
CYP2U1 -10449.0 -10397.0
CYP4F22 -11214.0 -10272.0
CYP7B1 -4766.0 -2364.0
CYSLTR1 2180.0 -8322.0
CYSLTR2 -2968.0 -8588.0
DAD1 5534.0 6325.0
DAG1 -8464.0 -2147.0
DAXX -10506.0 -3361.0
DBP -9793.0 -9412.0
DCXR -2729.0 2118.0
DDOST 459.0 8249.0
DDX5 -8723.0 -7926.0
DERL1 -8912.0 -3885.0
DERL2 4947.0 3337.0
DERL3 -8166.0 -4909.0
DHDDS -7112.0 3558.0
DLL1 -10099.0 -11006.0
DNAJC3 9077.0 8882.0
DOCK1 6941.0 8390.0
DOCK2 6433.0 8942.0
DOLK -6603.0 967.0
DPAGT1 6056.0 1306.0
DPEP2 -4986.0 -926.0
DPEP3 -4594.0 -1297.0
DPM1 3623.0 1708.0
DPM2 4659.0 5141.0
DPM3 -3178.0 5487.0
DUSP10 -2707.0 823.0
DUSP16 -4867.0 -5937.0
DUSP6 7994.0 2589.0
DUSP7 -4748.0 387.0
DUSP8 -10417.0 -9519.0
DUT -1529.0 -4503.0
DVL1 -1093.0 1894.0
DVL2 -10305.0 -7147.0
DVL3 -4437.0 8389.0
DYNC1H1 -8881.0 -2533.0
DYNC1I1 7141.0 2722.0
DYNC1I2 8160.0 8196.0
DYNC1LI1 7894.0 6997.0
DYNC1LI2 3494.0 5636.0
DYNLL1 6026.0 6499.0
DYNLL2 -6325.0 -225.0
E2F1 6782.0 6864.0
E2F2 6717.0 9388.0
E2F3 4978.0 7309.0
EDEM2 8210.0 9514.0
EED -4507.0 -6867.0
EEF2 -2498.0 2707.0
EGF 9244.0 8355.0
EIF2AK2 -8667.0 -6637.0
ELK1 -355.0 3195.0
ELL -4094.0 6433.0
ELMO1 4243.0 7282.0
ELMO2 -9506.0 6592.0
ELOA 8918.0 6756.0
ELOB 4867.0 8716.0
ELOC 6598.0 8484.0
ENO1 9509.0 9247.0
ENTPD1 9534.0 8418.0
ENTPD5 -991.0 -5130.0
EP300 4311.0 7552.0
EPM2A -6163.0 -10075.0
EPS15 6185.0 4175.0
ERBB2 -11251.0 -9287.0
ERBB3 3021.0 -1481.0
ERBIN 2164.0 -118.0
ERCC2 -795.0 5496.0
ERCC3 -9412.0 -2515.0
EREG -837.0 3226.0
ERLEC1 157.0 2344.0
ERLIN1 9781.0 9270.0
ERLIN2 8632.0 9807.0
ESR1 -6046.0 -8495.0
ESR2 -4206.0 -10115.0
ETV6 6776.0 5766.0
EXT1 5199.0 8182.0
EXT2 -6708.0 2518.0
EZH2 -4248.0 -9643.0
F12 10075.0 10096.0
F8 7498.0 7167.0
FADD -3611.0 7477.0
FAM114A2 5550.0 5072.0
FAM131B -7635.0 2425.0
FASLG -11268.0 -10430.0
FAU -5297.0 2810.0
FBXW7 -5277.0 -3657.0
FCGR1A 9965.0 9575.0
FCGR2A 9414.0 9249.0
FCGR3A -11272.0 -4672.0
FDX1 5786.0 1343.0
FDX2 -4897.0 -2162.0
FDXR 8050.0 3941.0
FEN1 -9669.0 -7661.0
FGF2 5967.0 3177.0
FGF22 -5885.0 -8493.0
FGF23 -3924.0 -7953.0
FGF7 158.0 -5338.0
FGF9 -8383.0 -6950.0
FGFR1 -8719.0 -822.0
FGFR1OP2 9863.0 6214.0
FGFR2 -10068.0 -10229.0
FGFR4 -1760.0 -2742.0
FGR 6254.0 9666.0
FIP1L1 -8488.0 -1467.0
FKBP1A 9920.0 8990.0
FKBP4 3798.0 1107.0
FMO3 -1277.0 477.0
FN1 10003.0 6211.0
FOXO1 -4402.0 -9319.0
FOXO3 8202.0 9854.0
FOXO4 -615.0 8296.0
FOXO6 -9309.0 -1189.0
FRS2 1765.0 -3137.0
FURIN 8111.0 10053.0
FUT8 -7539.0 -7706.0
FXR1 7067.0 5963.0
FXYD1 -6959.0 -3100.0
FXYD2 -384.0 -5695.0
FXYD3 -9980.0 -4578.0
FXYD6 8916.0 6736.0
FXYD7 -1051.0 -9615.0
FYN -10878.0 -6729.0
FZD4 -10858.0 -7985.0
FZD5 10104.0 10128.0
FZD6 -304.0 -7933.0
FZD7 -3752.0 -6423.0
FZD8 -9255.0 -2577.0
FZR1 -7787.0 2875.0
G6PC 5527.0 6482.0
G6PC3 -1222.0 5674.0
GAA 8448.0 8356.0
GAB1 7926.0 5272.0
GAB2 7546.0 9347.0
GALE -3883.0 7600.0
GALK1 7917.0 9843.0
GALNS 6719.0 8385.0
GALNT1 7249.0 6590.0
GALNT12 -4955.0 -9921.0
GALNT3 -9370.0 4339.0
GALT -3830.0 -9697.0
GANAB -8512.0 4203.0
GATAD2A -6815.0 5314.0
GATAD2B -7514.0 2232.0
GBE1 9173.0 8295.0
GCK 1371.0 1141.0
GCLC -9821.0 -9262.0
GCLM -2840.0 6348.0
GFPT1 -24.0 -5649.0
GGCX 4204.0 6743.0
GGT1 8068.0 10073.0
GGT5 -6888.0 1713.0
GIPR -10351.0 -11192.0
GLB1 9091.0 9091.0
GNAI1 6562.0 2097.0
GNAI2 5861.0 9258.0
GNAI3 9178.0 7726.0
GNAS 8297.0 8173.0
GNAZ 2560.0 3945.0
GNB1 6908.0 9175.0
GNB2 6587.0 9064.0
GNB3 7806.0 -8406.0
GNB4 9340.0 6537.0
GNB5 6182.0 -475.0
GNE -484.0 -3839.0
GNG10 9939.0 9753.0
GNG11 8239.0 6403.0
GNG2 -10761.0 192.0
GNG3 4993.0 -794.0
GNG4 414.0 -2445.0
GNG5 8894.0 9403.0
GNG7 -2881.0 -4054.0
GNG8 4092.0 4604.0
GNGT2 -11227.0 -6988.0
GNS 9627.0 10060.0
GOLGA2 -878.0 8019.0
GOLGA4 -783.0 -4010.0
GP1BA 6335.0 6875.0
GP1BB 7053.0 8670.0
GP5 6641.0 -1822.0
GP9 7524.0 8518.0
GPBAR1 -4023.0 -5612.0
GPC1 -6229.0 -1709.0
GPC2 736.0 -5447.0
GPC4 -2862.0 -5115.0
GPR15 -3654.0 -9482.0
GPR150 -8487.0 -10216.0
GPR20 -10975.0 -8440.0
GPR25 -10718.0 -6125.0
GPR27 9670.0 9900.0
GPR83 -4291.0 1630.0
GPR84 9267.0 9312.0
GPS2 -6562.0 2341.0
GRB2 9631.0 9985.0
GRSF1 8626.0 3839.0
GSK3A 5279.0 8683.0
GSK3B 6119.0 7526.0
GSS -1339.0 2936.0
GTF2A1 5229.0 2440.0
GTF2A2 8093.0 6862.0
GTF2B 5252.0 3578.0
GTF2E1 -940.0 4124.0
GTF2E2 1859.0 7023.0
GTF2F1 -3109.0 7342.0
GTF2F2 4728.0 6017.0
GTF2H1 6811.0 -4922.0
GTF2H2 4209.0 2786.0
GTF2H3 5560.0 -3551.0
GTF2H4 -5759.0 702.0
GTF2H5 7246.0 2946.0
GUCY2C 9823.0 9320.0
GUSB 2374.0 9501.0
GYG1 9474.0 9547.0
GYS1 6988.0 7692.0
H2AC11 7852.0 7819.0
H2AC20 -790.0 6112.0
H2AC6 8700.0 8169.0
H2AW -10705.0 -7332.0
H2BC11 8424.0 8288.0
H2BC12 9066.0 9812.0
H2BC15 3036.0 6455.0
H2BC17 7882.0 7312.0
H2BC18 4771.0 8130.0
H2BC21 9852.0 9656.0
H2BC4 7156.0 7805.0
H2BC5 7596.0 8773.0
H2BC9 7965.0 4715.0
H2BU1 -6349.0 -3895.0
H3C15 5262.5 7402.5
HBEGF 5089.0 5189.0
HCK 9286.0 9494.0
HDAC1 -3835.0 3708.0
HDAC10 -489.0 4165.0
HDAC11 804.0 5759.0
HDAC2 8973.0 3999.0
HDAC3 1719.0 6319.0
HDAC4 9329.0 9546.0
HDAC5 3359.0 5480.0
HDAC6 -7766.0 -5123.0
HDAC7 4750.0 7247.0
HDAC8 3980.0 4023.0
HDAC9 6738.0 -815.0
HES1 -10141.0 -3420.0
HEXA 1650.0 2356.0
HEXB 9386.0 9202.0
HGF 9753.0 8929.0
HGS -381.0 6840.0
HGSNAT 4689.0 2250.0
HHAT -6205.0 -8610.0
HK1 9170.0 9877.0
HLA-A -5067.0 570.0
HLCS -10615.0 -8779.0
HMG20B 2325.0 6041.0
HMGA1 2219.0 954.0
HNRNPK 7811.0 7654.0
HRAS -2248.0 -1932.0
HRH2 10051.0 10037.0
HSP90AA1 5309.0 410.0
HSP90AB1 2247.0 -6319.0
HSPA1A 8217.0 8368.0
HSPG2 -7219.0 -5674.0
HTR6 -288.0 -6092.0
HTR7 -774.0 -2330.0
HYAL1 888.0 4763.0
ICOS 1302.0 -10781.0
IDH1 10122.0 10092.0
IDS -7576.0 1999.0
IDUA -3629.0 -5066.0
IFNAR1 9272.0 8485.0
IFNAR2 4783.0 8002.0
IFNGR1 9796.0 9778.0
IFNGR2 9736.0 9781.0
IGHG1 -1124.0 -7111.0
IGHG2 -5587.0 -6004.0
IGHG3 -507.0 -4089.0
IGHG4 -4038.0 -5940.0
IGHV1-2 5956.0 -3146.0
IGHV1-46 3766.0 -2976.0
IGHV1-69 2354.0 -2328.0
IGHV2-5 4451.0 -1972.0
IGHV2-70 -3315.0 -2159.0
IGHV3-11 3518.0 -4591.0
IGHV3-13 799.0 -2451.0
IGHV3-23 6032.0 -5092.0
IGHV3-30 2500.0 -5193.0
IGHV3-33 98.0 -4138.0
IGHV3-48 3183.0 -4340.0
IGHV3-53 3131.0 -1786.0
IGHV3-7 4185.0 -3630.0
IGHV4-34 1144.0 -4007.0
IGHV4-39 3786.0 -6542.0
IGHV4-59 4532.0 -5870.0
IGKC 2773.0 -6437.0
IGKV1-12 725.0 -6674.0
IGKV1-16 6217.0 -5451.0
IGKV1-17 -241.0 -2794.0
IGKV1-33 5955.0 -6384.0
IGKV1-5 6127.0 -5162.0
IGKV1D-39 5018.0 -2677.0
IGKV2-28 1440.0 -6662.0
IGKV2-30 5205.0 -5349.0
IGKV2D-28 -7224.0 -2947.0
IGKV3-11 5548.0 -7167.0
IGKV3-15 3174.0 -4687.0
IGKV3-20 3704.0 -5021.0
IGKV3D-20 -1830.0 -4618.0
IGKV4-1 2812.0 -4988.0
IGKV5-2 5226.0 -2682.0
IGLC1 -2813.0 -6176.0
IGLC2 -258.0 -6539.0
IGLC3 -2958.0 -4378.0
IGLC7 -3403.0 -4490.0
IGLV1-36 3522.0 -5030.0
IGLV1-40 163.0 -5497.0
IGLV1-44 4742.0 -5791.0
IGLV1-47 231.0 -6633.0
IGLV1-51 1708.0 -6601.0
IGLV10-54 -5422.0 316.0
IGLV2-11 870.0 -3205.0
IGLV2-14 -5127.0 -8197.0
IGLV2-18 2015.0 -2963.0
IGLV2-23 2029.0 -4201.0
IGLV2-8 4818.0 -5256.0
IGLV3-1 -96.0 -5140.0
IGLV3-12 -7299.0 -6816.0
IGLV3-19 4006.0 -5611.0
IGLV3-21 -975.0 -6062.0
IGLV3-25 -942.0 -5485.0
IGLV3-27 -5365.0 -4834.0
IGLV4-69 1344.0 -2261.0
IGLV5-45 4194.0 -7364.0
IGLV6-57 1834.0 -5837.0
IGLV7-43 4854.0 -2823.0
IGLV7-46 2445.0 -3619.0
IGLV8-61 -3989.0 -5208.0
IKBKB -5276.0 -2118.0
IKBKG -3058.0 7903.0
IL10 9734.0 9799.0
IL18 8340.0 7387.0
IL1B 7489.0 3385.0
IL1R1 9455.0 9194.0
IL6R 9360.0 8189.0
IMPDH1 9819.0 9891.0
IMPDH2 -3563.0 -10154.0
INSL3 7991.0 6252.0
IPO5 -2034.0 -10616.0
IQGAP1 7310.0 9366.0
IRS1 6140.0 8.0
IRS2 8141.0 9618.0
ISG15 -10543.0 -10488.0
ITGA2B 9720.0 9409.0
ITGA4 -6795.0 -10195.0
ITGB1 3360.0 -108.0
ITGB3 9450.0 8690.0
ITPR1 -5546.0 -5368.0
ITPR2 6833.0 6418.0
ITPR3 -8438.0 -9066.0
JAG1 9550.0 8956.0
JAG2 -10015.0 -8085.0
JAK1 -10669.0 -4353.0
JAK2 7618.0 374.0
JAK3 8703.0 8585.0
JUN 2838.0 4810.0
KANK1 3022.0 -7617.0
KAT2A -6742.0 -10405.0
KAT2B 116.0 -1532.0
KCNJ11 -2546.0 -3545.0
KDM1A -6245.0 -6064.0
KDM7A 8052.0 6799.0
KHK -6419.0 -4987.0
KIAA1549 7040.0 2139.0
KIT -10872.0 -8011.0
KL 9145.0 9846.0
KLKB1 -3621.0 -9856.0
KPNA1 4214.0 1618.0
KPNA2 -7397.0 -3307.0
KPNA3 4907.0 248.0
KPNA4 4184.0 4979.0
KPNA5 -6929.0 -11243.0
KPNB1 -1223.0 3575.0
KRAS 3789.0 4070.0
KREMEN1 8950.0 9970.0
KREMEN2 -6004.0 4016.0
KSR1 326.0 5540.0
KSR2 -3767.0 -1942.0
LARGE1 -4555.0 -5687.0
LCK -10358.0 -10719.0
LFNG -9497.0 -3283.0
LIG1 -6335.0 -10666.0
LIG4 6390.0 5361.0
LMBRD1 8148.0 6388.0
LMNA 1706.0 5027.0
LMNB1 9994.0 9773.0
LRP5 5683.0 4611.0
LRP6 3999.0 -1401.0
LRRFIP1 6242.0 6811.0
LTF 9374.0 3485.0
LY96 9529.0 8995.0
LYN 7575.0 8379.0
MAGT1 574.0 3711.0
MAML1 -81.0 7084.0
MAML2 3788.0 -1483.0
MAML3 9463.0 9534.0
MAMLD1 -532.0 -6686.0
MAN1B1 -7203.0 -495.0
MAN2A1 5542.0 -2948.0
MAOA 9886.0 9426.0
MAP1LC3B 7597.0 8663.0
MAP2K1 9163.0 9879.0
MAP2K2 185.0 8452.0
MAP2K3 8978.0 9308.0
MAP2K4 6895.0 7431.0
MAP2K6 9435.0 9577.0
MAP2K7 -2754.0 4813.0
MAP3K11 6025.0 8985.0
MAPK1 1052.0 9260.0
MAPK14 9907.0 9606.0
MAPK3 8931.0 9626.0
MAPK8 -1061.0 -9914.0
MAPKAP1 2536.0 5925.0
MARK3 9434.0 9486.0
MBD3 -247.0 1576.0
MC1R -10590.0 -8703.0
MCCC1 -4948.0 -7307.0
MCCC2 -7378.0 -10977.0
MDM2 7204.0 3892.0
MECP2 -10579.0 -5423.0
MEFV 9094.0 9246.0
MGAT1 2229.0 8361.0
MGAT2 -5319.0 4067.0
MGAT4A -3305.0 -4301.0
MGAT4B 9276.0 9187.0
MGAT4C 3599.0 -4032.0
MGAT5 -5440.0 -102.0
MIB1 3219.0 -3926.0
MIB2 -10461.0 -7734.0
MLH1 -6822.0 -1914.0
MLST8 -3991.0 2978.0
MMAA -7883.0 -9948.0
MMAB -6760.0 -7369.0
MMACHC -439.0 -6769.0
MMADHC 6035.0 6340.0
MMUT 5151.0 3819.0
MNAT1 -7347.0 -6614.0
MOGS -5970.0 1434.0
MPDU1 7358.0 8337.0
MPI -6079.0 -9414.0
MPRIP -9471.0 -9503.0
MRAS -10710.0 298.0
MRC1 -6259.0 4719.0
MSH2 -7268.0 -9966.0
MSH3 5093.0 7212.0
MSH6 3793.0 -2370.0
MTA1 -550.0 -1521.0
MTA2 -10115.0 863.0
MTA3 -7862.0 -7132.0
MTOR -10419.0 -3248.0
MTR -9160.0 -11143.0
MTRR -620.0 3303.0
MUC1 8159.0 7011.0
MUC12 -8506.0 -9690.0
MUC16 377.0 -5584.0
MUC20 -2625.0 -6328.0
MUC4 643.0 -4710.0
MUC5B -8416.0 -622.0
MUC6 -3460.0 -1745.0
MUCL1 -1878.0 -1414.0
MUTYH -9035.0 -9233.0
MVB12A 6023.0 8501.0
MVB12B 2755.0 6228.0
MYC 8429.0 -2186.0
MYD88 8651.0 8344.0
MYH9 1879.0 8348.0
MYO10 9409.0 9473.0
MYO18A -8578.0 2221.0
MYO1C 6395.0 2929.0
MYO5A 6789.0 7727.0
MYO9B 513.0 8592.0
NAGLU -9789.0 2532.0
NAPEPLD 3207.0 -8341.0
NCBP1 1766.0 -6055.0
NCBP2 3719.0 -10143.0
NCK1 -9250.0 -9113.0
NCKAP1 6871.0 8168.0
NCKAP1L 3966.0 9566.0
NCKIPSD 957.0 1858.0
NCOR1 3309.0 7790.0
NCOR2 4843.0 9646.0
NCSTN 9503.0 9869.0
NDC1 -9151.0 -11223.0
NEDD4L 8246.0 8260.0
NEIL1 -9117.0 -4853.0
NEIL3 1308.0 1620.0
NELFA -2921.0 -970.0
NELFB -8446.0 5056.0
NELFCD -3646.0 -4090.0
NELFE -4877.0 6342.0
NEU1 9336.0 9571.0
NEURL1 -11174.0 -6488.0
NEURL1B -9540.0 2352.0
NF1 -1234.0 4267.0
NFKB1 7857.0 6377.0
NFKB2 3069.0 -1167.0
NFKBIA 6855.0 7374.0
NHLRC1 -8568.0 -610.0
NLRP3 9708.0 8944.0
NMT1 -372.0 6750.0
NMT2 -9645.0 -11173.0
NOTCH1 -6446.0 6708.0
NOTCH2 4412.0 6414.0
NOTCH3 -744.0 9587.0
NOTCH4 -10586.0 1602.0
NOXA1 -2600.0 -5589.0
NPM1 306.0 -10502.0
NR3C1 -5002.0 2698.0
NR4A1 -7773.0 -6467.0
NRAS 7321.0 4878.0
NRG1 8713.0 914.0
NRG4 1196.0 -3291.0
NT5E -2269.0 -7078.0
NTHL1 -7967.0 -4842.0
NUP107 -4463.0 -10317.0
NUP133 -4339.0 -4616.0
NUP153 -7195.0 -2408.0
NUP155 -4644.0 -9292.0
NUP160 -2518.0 -10020.0
NUP188 -9467.0 -9810.0
NUP205 -8533.0 -9667.0
NUP210 -10480.0 -5943.0
NUP214 8588.0 8152.0
NUP35 -4281.0 -10256.0
NUP37 3188.0 3613.0
NUP42 1567.0 -5400.0
NUP43 -55.0 -10161.0
NUP50 6614.0 4617.0
NUP54 2794.0 -9194.0
NUP58 9637.0 9212.0
NUP62 3053.0 1921.0
NUP85 1119.0 -2732.0
NUP88 -7116.0 -10078.0
NUP93 -9095.0 -8944.0
NUP98 208.0 4310.0
NUS1 9194.0 7298.0
OGG1 -6768.0 -5403.0
OPLAH 10032.0 9930.0
OS9 8889.0 9708.0
P2RX4 7118.0 8994.0
P2RX7 5741.0 3066.0
P2RY11 -10046.0 -8647.0
PABPN1 -3570.0 2770.0
PACS1 -9558.0 -3284.0
PAK2 9019.0 8433.0
PAPSS1 9369.0 9581.0
PAPSS2 -10676.0 2940.0
PARP1 -10438.0 -8545.0
PARP10 -9335.0 -4173.0
PARP14 -8685.0 -10901.0
PARP16 -10582.0 -9753.0
PARP4 13.0 6081.0
PARP6 -4204.0 -3339.0
PARP8 -6730.0 -6159.0
PARP9 1298.0 -3808.0
PC 9686.0 9800.0
PCCA -5749.0 -6966.0
PCCB -7266.0 -3557.0
PDCD1 -7403.0 -5037.0
PDCD6IP 7627.0 7201.0
PDGFA 6115.0 5392.0
PDGFB -4645.0 -8897.0
PDGFRA 2481.0 6753.0
PDGFRB -11134.0 -5992.0
PDPK1 2392.0 7816.0
PDZD3 -1284.0 4430.0
PEBP1 -8004.0 -10339.0
PGK1 9349.0 8950.0
PGM1 -2421.0 7047.0
PHB -4398.0 564.0
PHF21A 9412.0 10047.0
PIK3AP1 6149.0 8581.0
PIK3C3 6605.0 573.0
PIK3CA 6889.0 4182.0
PIK3CB 9838.0 9248.0
PIK3CD 82.0 7288.0
PIK3R1 -7197.0 -8942.0
PIK3R2 2459.0 5820.0
PIK3R3 -11107.0 -8159.0
PIK3R4 -267.0 -2209.0
PLCG1 -6360.0 -11043.0
PLCG2 -4618.0 6826.0
PLK2 -4874.0 -658.0
PML -6449.0 -6720.0
PMM2 7431.0 -439.0
PMS2 -1668.0 -4409.0
POLR2A -8726.0 2901.0
POLR2B -1034.0 188.0
POLR2C -2183.0 3527.0
POLR2D 3401.0 -4083.0
POLR2E 6766.0 8343.0
POLR2F -2307.0 6746.0
POLR2G -5778.0 6576.0
POLR2H 653.0 -2264.0
POLR2I -2123.0 2695.0
POLR2J 4448.0 7822.0
POLR2K 1881.0 -1885.0
POLR2L 126.0 7246.0
POM121 -8969.0 -3230.0
POM121C -9525.0 -1010.0
POMC 1489.0 3391.0
POMGNT1 -10525.0 -9638.0
POMT1 -3743.0 -8982.0
POMT2 -619.0 2396.0
PORCN -9834.0 -6886.0
PPIA -7248.0 -2108.0
PPP1CB 8657.0 6666.0
PPP1CC 9200.0 4868.0
PPP2CA 8810.0 8328.0
PPP2CB 8482.0 7631.0
PPP2R1A -3087.0 6994.0
PPP2R1B 2503.0 437.0
PPP2R5A -903.0 6957.0
PPP2R5B 5288.0 7952.0
PPP2R5C -10420.0 -7112.0
PPP2R5D -6508.0 4985.0
PPP2R5E 715.0 540.0
PRDX1 8521.0 6488.0
PRDX2 6558.0 2663.0
PRELP 3029.0 -3227.0
PRKACA 9885.0 10068.0
PRKACB -9852.0 -10936.0
PRKAR1A 8455.0 9570.0
PRKAR1B 8879.0 7874.0
PRKAR2A 3755.0 7093.0
PRKAR2B 7943.0 7189.0
PRKCSH -3697.0 7582.0
PRKX -5579.0 -9049.0
PRR5 -11173.0 -8620.0
PSEN1 7889.0 8878.0
PSEN2 -5169.0 -5867.0
PSENEN 2692.0 7551.0
PSIP1 607.0 -10197.0
PSMA1 8278.0 7406.0
PSMA2 5830.0 5666.0
PSMA3 4646.0 -7621.0
PSMA4 3950.0 -1036.0
PSMA5 -2119.0 -3983.0
PSMA6 6893.0 5865.0
PSMA7 3550.0 8554.0
PSMB1 3915.0 4224.0
PSMB10 -7878.0 -1272.0
PSMB2 2664.0 4928.0
PSMB3 4971.0 8382.0
PSMB4 -3175.0 4911.0
PSMB5 6561.0 9138.0
PSMB6 1312.0 8784.0
PSMB7 8034.0 9051.0
PSMB8 -4481.0 75.0
PSMB9 -9105.0 -10433.0
PSMC1 6759.0 7782.0
PSMC2 -2524.0 4517.0
PSMC3 -4971.0 4984.0
PSMC4 -10757.0 -336.0
PSMC5 -3424.0 2764.0
PSMC6 8812.0 6000.0
PSMD1 7679.0 7587.0
PSMD10 2067.0 2450.0
PSMD11 6914.0 6824.0
PSMD12 9011.0 5710.0
PSMD13 3157.0 7205.0
PSMD14 2891.0 3041.0
PSMD2 4352.0 8396.0
PSMD3 -2243.0 6367.0
PSMD4 6858.0 9449.0
PSMD5 2770.0 4781.0
PSMD6 8841.0 8304.0
PSMD7 6534.0 6147.0
PSMD8 739.0 7117.0
PSMD9 3580.0 9001.0
PSME1 -7256.0 -7913.0
PSME2 -5548.0 -10355.0
PSME3 9120.0 8239.0
PSME4 -5205.0 -3127.0
PSMF1 6709.0 6770.0
PSTPIP1 4146.0 9452.0
PTEN 9191.0 8752.0
PTGDR -11236.0 -8923.0
PTGER2 -1945.0 2934.0
PTGER4 -10608.0 -8098.0
PTGES3 8385.0 2175.0
PTGIR -8467.0 -6760.0
PTK2 7786.0 3481.0
PTPN11 4691.0 6614.0
PTPN12 7921.0 9275.0
PYCARD 8329.0 9425.0
QKI 9569.0 9736.0
RAB5A 8478.0 6815.0
RAB7A 8897.0 9367.0
RAC1 9052.0 9614.0
RAC2 -7677.0 6828.0
RAE1 4777.0 6291.0
RAF1 8477.0 8327.0
RAMP1 -10784.0 851.0
RAN -2391.0 -4763.0
RANBP1 -6384.0 -8275.0
RANBP2 4453.0 -2222.0
RANGAP1 -10259.0 -9220.0
RAP1A 8688.0 6973.0
RAP1B -2703.0 4941.0
RB1 9490.0 8828.0
RBBP4 4016.0 -1020.0
RBBP7 -10846.0 -9848.0
RBPJ 9652.0 9125.0
RBX1 1418.0 4877.0
RCC1 -1801.0 3857.0
RCOR1 9795.0 9655.0
RDH5 670.0 1182.0
RELA -7305.0 2739.0
REST 534.0 1614.0
RFT1 7279.0 3586.0
RHBDF2 -6081.0 7719.0
RHOG 7549.0 9255.0
RICTOR -3978.0 -9726.0
RIPK1 -10879.0 -4699.0
RLN2 -3997.0 -8672.0
RLN3 -3200.0 7456.0
RNF185 3476.0 7488.0
RNF213 -10439.0 -9870.0
RNF43 -9524.0 -11210.0
RNF5 -8439.0 -1294.0
RNGTT 4100.0 3117.0
RNMT -5165.0 -10609.0
ROCK1 8315.0 7930.0
ROCK2 7628.0 6719.0
RPIA 4409.0 1808.0
RPL10 -5353.0 -4722.0
RPL10A -1883.0 -6533.0
RPL11 -1931.0 -5590.0
RPL12 -4453.0 -5830.0
RPL13 -1749.0 -2925.0
RPL13A -5236.0 -7060.0
RPL14 -3538.0 -6408.0
RPL15 2144.0 -270.0
RPL17 -2803.0 -4216.0
RPL18 -2407.0 -4107.0
RPL18A -4338.0 -4740.0
RPL19 -5605.0 -4047.0
RPL21 -2408.0 -6412.0
RPL22 1616.0 -5576.0
RPL22L1 3994.0 -3396.0
RPL23 -353.0 -2321.0
RPL23A -4695.0 -9373.0
RPL24 -3568.0 -4504.0
RPL26 -4494.0 -4767.0
RPL26L1 6548.0 7865.0
RPL27 -3684.0 -361.0
RPL27A -5814.0 -4093.0
RPL28 -2567.0 614.0
RPL29 -2138.0 -1913.0
RPL3 -6886.0 -7461.0
RPL30 -5225.0 -5596.0
RPL31 -2656.0 -3267.0
RPL32 -3094.0 -6607.0
RPL34 -2097.0 -7114.0
RPL35 -8453.0 -5007.0
RPL35A -2671.0 -5323.0
RPL36 -6761.0 -2662.0
RPL36A -5740.0 -5975.0
RPL36AL -1773.0 1920.0
RPL37 -8529.0 -2184.0
RPL37A -5802.0 -727.0
RPL38 -7075.0 -2793.0
RPL39 -983.0 -3231.0
RPL39L -10310.0 -4203.0
RPL4 2174.0 -3722.0
RPL41 -7404.0 -3692.0
RPL5 2979.0 -5487.0
RPL6 3510.0 -3949.0
RPL7 3811.0 -2799.0
RPL7A -2851.0 -1500.0
RPL8 -4534.0 1780.0
RPL9 -167.0 -2256.0
RPLP0 3127.0 -1531.0
RPLP1 -2483.0 2491.0
RPLP2 -7230.0 -4974.0
RPN1 7629.0 8737.0
RPN2 5890.0 7636.0
RPS10 -5228.0 -3784.0
RPS11 -7652.0 -3921.0
RPS12 -4698.0 -5458.0
RPS13 3315.0 -2060.0
RPS14 -6862.0 -2786.0
RPS15 -4712.0 -988.0
RPS15A -3464.0 -4486.0
RPS16 -3811.0 -3249.0
RPS17 -6899.0 -3309.0
RPS18 -6859.0 -6415.0
RPS19 -5797.0 -5539.0
RPS2 -6072.0 -1316.0
RPS20 -6536.0 -7674.0
RPS21 -4436.0 -2455.0
RPS23 -1921.0 -5872.0
RPS24 3926.0 -838.0
RPS25 -1359.0 -6741.0
RPS26 -1177.0 -1112.0
RPS27 -9041.0 -7909.0
RPS27A -3555.0 -7070.0
RPS27L 5307.0 1458.0
RPS28 -5391.0 -2679.0
RPS29 -8497.0 -5396.0
RPS3 -4098.0 -4595.0
RPS3A 3428.0 -6271.0
RPS4X -1869.0 -6447.0
RPS4Y1 5773.0 -56.0
RPS5 -4290.0 -4473.0
RPS6 -1613.0 -5951.0
RPS6KB2 -4855.0 4416.0
RPS7 -1789.0 -4131.0
RPS8 2338.0 -2478.0
RPS9 3357.0 6145.0
RPSA -2286.0 -5572.0
RXFP2 9389.0 5911.0
S1PR1 -10750.0 -4787.0
SAP18 3103.0 5947.0
SAP30 8514.0 8741.0
SAP30L -280.0 6304.0
SBSPON -553.0 -8704.0
SCT -10916.0 -9122.0
SDC2 7232.0 4710.0
SDC3 3723.0 2630.0
SDC4 6516.0 7115.0
SEC13 2125.0 6861.0
SEH1L 7189.0 -8511.0
SEL1L 7157.0 7252.0
SEM1 993.0 5942.0
SEMA5A -7754.0 -9477.0
SEMA5B -1476.0 3843.0
SERPING1 -6329.0 -10968.0
SFPQ 8031.0 -220.0
SFTPB 4839.0 633.0
SFTPD -11105.0 -7143.0
SGSH 6255.0 6622.0
SH3GL1 4634.0 8807.0
SH3KBP1 4345.0 7311.0
SHC1 -3416.0 5815.0
SHOC2 8573.0 7262.0
SIGMAR1 -6432.0 -4538.0
SIN3A -9037.0 -7770.0
SKP1 8120.0 2700.0
SKP2 -2615.0 -7161.0
SLC11A2 3408.0 211.0
SLC12A1 5311.0 1287.0
SLC12A3 -11066.0 -7173.0
SLC12A6 8049.0 8895.0
SLC16A1 7992.0 3127.0
SLC17A5 3558.0 5793.0
SLC1A3 9671.0 9889.0
SLC20A2 -10973.0 -5662.0
SLC22A18 3118.0 4851.0
SLC22A5 8129.0 6640.0
SLC24A1 -9823.0 -8533.0
SLC24A4 8871.0 7763.0
SLC25A4 -9712.0 -10587.0
SLC25A5 -2120.0 2904.0
SLC25A6 1188.0 8323.0
SLC26A2 -2767.0 -643.0
SLC27A4 -5321.0 5621.0
SLC29A3 1184.0 6100.0
SLC2A1 -11011.0 -6196.0
SLC2A10 -4010.0 -4079.0
SLC2A9 9391.0 5291.0
SLC33A1 1768.0 -1430.0
SLC34A1 -6058.0 865.0
SLC34A2 6195.0 -1412.0
SLC34A3 -7246.0 -5460.0
SLC35A1 9102.0 6415.0
SLC35A2 -8815.0 6460.0
SLC35A3 -474.0 -9691.0
SLC35C1 1561.0 3694.0
SLC35D1 -5746.0 -4085.0
SLC36A2 -6167.0 1367.0
SLC37A4 -5208.0 -4132.0
SLC39A4 3879.0 5035.0
SLC3A1 -8293.0 -6078.0
SLC3A2 200.0 6877.0
SLC40A1 9430.0 7018.0
SLC4A1 10074.0 8897.0
SLC4A4 -11006.0 -8671.0
SLC5A2 666.0 -5529.0
SLC5A5 4358.0 -8309.0
SLC6A20 -5383.0 -3251.0
SLC7A7 7699.0 7341.0
SLC9A6 2707.0 5538.0
SLC9A9 7672.0 7876.0
SMAD2 5238.0 5871.0
SMAD3 -10084.0 -10081.0
SMAD4 -3009.0 -6696.0
SND1 -82.0 6307.0
SNF8 2113.0 7859.0
SNW1 6824.0 5161.0
SOD2 4529.0 4854.0
SOS1 3534.0 -7412.0
SPON1 -5400.0 -9627.0
SPON2 -11244.0 -8318.0
SPRED1 -7983.0 -6504.0
SPRED2 -404.0 8453.0
SPRED3 -6894.0 -4695.0
SRC -6857.0 -7229.0
SRD5A3 3417.0 4347.0
SSRP1 -9188.0 -7998.0
ST3GAL1 -6884.0 -3859.0
ST3GAL2 7832.0 9657.0
ST3GAL3 2775.0 828.0
ST3GAL4 -9921.0 7993.0
ST6GAL1 -10673.0 -10107.0
ST6GALNAC2 6233.0 7200.0
ST6GALNAC3 8893.0 9823.0
ST6GALNAC4 -4762.0 1735.0
STAM 3046.0 2017.0
STAM2 8115.0 5912.0
STAT1 -7385.0 -11118.0
STAT2 -5116.0 -9909.0
STAT3 8512.0 8606.0
STAT5A 6437.0 7973.0
STAT5B 4758.0 7433.0
STRN 215.0 5171.0
STT3A 3820.0 5008.0
STX1A -9454.0 1322.0
STX1B 2007.0 -4381.0
SUDS3 6591.0 4895.0
SUGT1 7602.0 -482.0
SUMO1 7968.0 6798.0
SUPT16H -8035.0 -9349.0
SUPT4H1 -3945.0 5159.0
SUPT5H -7894.0 -1035.0
SUZ12 4539.0 -3535.0
SV2A -8001.0 -10175.0
SV2B 7.0 -1906.0
SV2C 1160.0 -3759.0
SYK 9464.0 9848.0
SYT1 6818.0 4381.0
SYT2 -9931.0 3980.0
SYVN1 734.0 2029.0
TAF1 -7966.0 -4835.0
TAF10 2322.0 8682.0
TAF11 -704.0 -1109.0
TAF12 7812.0 8713.0
TAF13 7701.0 7806.0
TAF15 -8799.0 -1577.0
TAF2 -4065.0 -3670.0
TAF3 4012.0 -2596.0
TAF4 -3572.0 1348.0
TAF4B 2362.0 -8920.0
TAF5 2036.0 -3946.0
TAF6 -9400.0 -1340.0
TAF7 -1675.0 3464.0
TAF9 7182.0 -980.0
TAF9B 6761.0 -6403.0
TALDO1 10039.0 9995.0
TBK1 5846.0 2973.0
TBL1X 8359.0 8499.0
TBL1XR1 4714.0 4779.0
TBP -1224.0 -8870.0
TBXAS1 9105.0 9461.0
TCEA1 5155.0 -1614.0
TCF7L2 -10402.0 -1302.0
TCN2 9169.0 9144.0
TENT4A -6785.0 -10789.0
TFDP1 9824.0 8225.0
TFDP2 -11249.0 -10144.0
TGFA 7935.0 9686.0
TGFB1 -2566.0 6745.0
TGFBR1 -7960.0 3224.0
TGFBR2 -5037.0 6173.0
THBS1 1778.0 8102.0
THSD1 -3671.0 -6837.0
THSD4 -4394.0 -1859.0
THSD7A -6799.0 -6728.0
TICAM1 6742.0 6552.0
TIRAP 262.0 7730.0
TLN1 7865.0 9661.0
TLR1 9828.0 8868.0
TLR10 -122.0 -3607.0
TLR2 9930.0 9118.0
TLR3 -9935.0 -9836.0
TLR4 9494.0 9617.0
TLR5 9746.0 9721.0
TLR6 9634.0 9209.0
TLR7 8636.0 -4675.0
TLR9 -10413.0 -138.0
TNKS -7769.0 -6024.0
TNKS2 604.0 1179.0
TPMT 5197.0 4466.0
TPR -1066.0 -7983.0
TPST1 9124.0 9903.0
TPST2 -8995.0 8264.0
TRADD 4485.0 -2275.0
TRAF2 -9898.0 -9879.0
TRAF3 2694.0 -5265.0
TRAK1 4501.0 6029.0
TRAT1 5825.0 -10715.0
TRIM24 7340.0 2782.0
TRIM27 9047.0 8593.0
TRIM28 -4783.0 -1562.0
TSC2 -4535.0 2859.0
TSG101 8461.0 7757.0
TSHR 5881.0 -42.0
TUBB -9096.0 -626.0
TXN 8317.0 8729.0
TXNIP -9337.0 -6548.0
TXNRD1 8327.0 8699.0
TYK2 4430.0 8605.0
UBA52 -1875.0 3023.0
UBAP1 9074.0 9269.0
UBB 8251.0 6157.0
UBC -1915.0 5825.0
UBE2C 3717.0 5687.0
UBE2D1 9825.0 9491.0
UBE2E1 8528.0 6289.0
UBE2I -4201.0 2754.0
UBE2S 3693.0 5680.0
UGT1A1 -1062.0 2528.0
UNC93B1 -1309.0 6224.0
UVRAG -3806.0 -6609.0
VAMP1 -5776.0 -7557.0
VAMP2 -9677.0 -10779.0
VAV1 5553.0 8731.0
VAV2 -5033.0 -1339.0
VAV3 -6160.0 7203.0
VCAN 10068.0 10125.0
VCL 7488.0 7955.0
VCP 3600.0 7754.0
VEGFA 8464.0 8215.0
VHL -212.0 6007.0
VIPR1 -2635.0 -5038.0
VIPR2 -11038.0 -10105.0
VPS25 4731.0 8821.0
VPS28 388.0 6727.0
VPS33B -9608.0 4599.0
VPS36 2419.0 -7295.0
VPS37A 7815.0 6346.0
VPS37B -9566.0 6955.0
VPS37C 8342.0 8556.0
VPS4A -5744.0 4778.0
VPS4B 5540.0 5495.0
VTA1 7807.0 5732.0
VWF 6949.0 7780.0
WAS 8258.0 9323.0
WASF1 10091.0 10132.0
WASF2 7535.0 9576.0
WASF3 8142.0 7240.0
WASL 899.0 1391.0
WDR48 -7124.0 -9778.0
WIPF1 -5700.0 3866.0
WIPF2 2722.0 7125.0
XPO1 6563.0 -3235.0
XRCC4 7049.0 7016.0
XRCC5 6475.0 5318.0
XRCC6 -2658.0 -1055.0
YES1 -11138.0 -8566.0
YWHAB 8274.0 6101.0
YWHAE 9721.0 9563.0
ZBP1 -11073.0 -10810.0
ZC3HAV1 -5479.0 -8568.0
ZCRB1 2608.0 386.0
ZFYVE9 -4592.0 -7944.0
ZMYM2 5946.0 3690.0



Asparagine N-linked glycosylation

Asparagine N-linked glycosylation
metric value
setSize 269
pMANOVA 4.8e-18
p.adjustMANOVA 4.09e-16
s.dist 0.367
s.low.CRP 0.187
s.high.CRP 0.316
p.low.CRP 1.32e-07
p.high.CRP 4.39e-19




Top 20 genes
Gene low CRP high CRP
CTSA 10083 10131
NPL 10063 10123
F5 10084 10070
ASGR2 10000 10129
SERPINA1 9571 9817
ASGR1 9847 9456
ARF4 9859 9444
SPTB 9958 9302
KDELR1 9552 9681
CD55 9326 9842
RAB1A 9700 9407
NEU1 9336 9571
CTSZ 8972 9860
RAD23B 9180 9565
ST6GALNAC3 8893 9823
OS9 8889 9708
NSF 8895 9680
MGAT4B 9276 9187
DCTN2 8504 10012
CMAS 9548 8906

Click HERE to show all gene set members

All member genes
low CRP high CRP
ACTR10 8589 7569
ACTR1A -2833 8680
ALG1 -9753 -1781
ALG10 -6726 -6482
ALG10B 1984 -9722
ALG11 -3019 -1403
ALG12 -787 4333
ALG13 -1043 -8422
ALG14 7527 5733
ALG2 3111 -119
ALG3 2590 -813
ALG5 4020 -1165
ALG6 5735 527
ALG8 4756 -5192
ALG9 -6685 -8829
AMDHD2 -10278 -6693
AMFR 8281 7316
ANK1 9797 8626
ANK3 3262 -7407
ANKRD28 -5795 -3898
ARCN1 4082 6402
AREG 4465 7165
ARF1 8465 9910
ARF3 5651 9049
ARF4 9859 9444
ARF5 5736 9180
ARFGAP1 -6136 2991
ARFGAP2 -8987 2096
ARFGAP3 -6040 5157
ASGR1 9847 9456
ASGR2 10000 10129
B4GALNT2 -601 2343
B4GALT1 -4177 7099
B4GALT2 -7253 -2349
B4GALT3 -9162 -7981
B4GALT4 -9971 3971
B4GALT5 8862 9469
B4GALT6 -10936 -1047
BET1 7030 -4395
BET1L -7832 -2582
CALR 6685 6374
CANX 6838 5751
CAPZA1 8666 8511
CAPZA2 9698 8474
CAPZB 6100 8926
CD55 9326 9842
CD59 4075 5772
CHST10 -11043 -8384
CHST8 2634 6673
CMAS 9548 8906
CNIH1 9316 7116
CNIH2 701 601
CNIH3 -8173 -6989
COG1 -10399 -10838
COG2 -1210 -5915
COG3 3891 -5333
COG4 -4813 2002
COG5 1617 -3368
COG6 1512 -6280
COG7 2191 6149
COG8 -2814 2839
COL7A1 3993 7683
COPA 7617 9591
COPB1 8213 7283
COPB2 8531 8034
COPE 365 8719
COPG1 2542 9195
COPG2 7905 8313
COPZ1 2549 5017
COPZ2 -9229 -9247
CSNK1D -10030 6117
CTSA 10083 10131
CTSC -7528 5285
CTSZ 8972 9860
DAD1 5534 6325
DCTN1 -5984 7873
DCTN2 8504 10012
DCTN3 325 7904
DCTN4 7967 9572
DCTN5 -7505 664
DCTN6 7871 7759
DDOST 459 8249
DERL1 -8912 -3885
DERL2 4947 3337
DHDDS -7112 3558
DOLK -6603 967
DOLPP1 3438 3524
DPAGT1 6056 1306
DPM1 3623 1708
DPM2 4659 5141
DPM3 -3178 5487
DYNC1H1 -8881 -2533
DYNC1I1 7141 2722
DYNC1I2 8160 8196
DYNC1LI1 7894 6997
DYNC1LI2 3494 5636
DYNLL1 6026 6499
DYNLL2 -6325 -225
EDEM1 3521 253
EDEM2 8210 9514
EDEM3 9762 8422
ENGASE -5841 -6317
F5 10084 10070
F8 7498 7167
FCSK -1802 4404
FPGT 8997 6942
FUCA1 8013 8533
FUOM -3125 -3604
FUT8 -7539 -7706
GANAB -8512 4203
GBF1 -8933 1807
GFPT1 -24 -5649
GFPT2 -9716 -7397
GLB1 9091 9091
GMDS 4877 5289
GMPPA 1299 5440
GMPPB -7578 -3166
GNE -484 -3839
GNPNAT1 4439 -10903
GOLGA2 -878 8019
GOLGB1 -242 -5768
GORASP1 7651 6560
GOSR1 -4021 2971
GOSR2 -2437 1468
KDELR1 9552 9681
KDELR2 8771 7531
KDELR3 2255 -3318
LMAN1 -1255 -10522
LMAN2 2397 8522
LMAN2L 7675 6680
MAGT1 574 3711
MAN1A1 4965 9297
MAN1A2 -1459 -993
MAN1B1 -7203 -495
MAN1C1 1436 -8761
MAN2A1 5542 -2948
MAN2A2 1864 8354
MANEA 6711 -5721
MARCHF6 -3247 -1277
MCFD2 7963 7485
MGAT1 2229 8361
MGAT2 -5319 4067
MGAT3 2892 -5080
MGAT4A -3305 -4301
MGAT4B 9276 9187
MGAT4C 3599 -4032
MGAT5 -5440 -102
MIA2 6640 5566
MIA3 3397 -6425
MLEC 1226 3680
MOGS -5970 1434
MPDU1 7358 8337
MPI -6079 -9414
MVD -10176 2670
NAGK 6329 2553
NANP -8562 -6438
NANS 8296 8165
NAPA -2447 3305
NAPB -291 -2004
NAPG 7409 3591
NEU1 9336 9571
NEU3 -1390 -1896
NGLY1 -86 -2388
NPL 10063 10123
NSF 8895 9680
NUDT14 -3679 -4528
NUS1 9194 7298
OS9 8889 9708
PDIA3 2037 4838
PGM3 7906 -5172
PMM1 -3254 6102
PMM2 7431 -439
PPP6C 8559 6316
PPP6R1 -5320 7658
PPP6R3 3008 3925
PREB -1638 8142
PRKCSH -3697 7582
PSMC1 6759 7782
RAB1A 9700 9407
RAB1B 5676 9455
RAD23B 9180 9565
RENBP 6011 7767
RFT1 7279 3586
RNF103 -5944 2
RNF139 1735 3515
RNF185 3476 7488
RNF5 -8439 -1294
RPN1 7629 8737
RPN2 5890 7636
RPS27A -3555 -7070
SAR1B 8795 5984
SCFD1 4551 3924
SEC13 2125 6861
SEC16A -2929 6748
SEC16B -1454 1213
SEC22A 374 -4424
SEC22B 8663 4943
SEC22C -2377 -1611
SEC23A 8776 6905
SEC23IP 5231 -574
SEC24A 8318 7788
SEC24B 1663 5398
SEC24C -9662 3561
SEC24D 8017 8795
SEC31A 1743 2474
SEL1L 7157 7252
SERPINA1 9571 9817
SLC17A5 3558 5793
SLC35A1 9102 6415
SLC35C1 1561 3694
SPTA1 9470 6216
SPTAN1 -10174 -8889
SPTB 9958 9302
SPTBN1 -6572 -6164
SPTBN2 -5447 -3871
SPTBN5 -7557 -461
SRD5A3 3417 4347
ST3GAL1 -6884 -3859
ST3GAL2 7832 9657
ST3GAL3 2775 828
ST3GAL4 -9921 7993
ST3GAL5 -8483 -10211
ST3GAL6 9317 5155
ST6GAL1 -10673 -10107
ST6GAL2 -6498 1859
ST6GALNAC1 1128 -7500
ST6GALNAC2 6233 7200
ST6GALNAC3 8893 9823
ST6GALNAC4 -4762 1735
ST6GALNAC6 -10863 -9916
ST8SIA1 160 -9368
ST8SIA4 9016 8665
ST8SIA5 317 2482
ST8SIA6 -10982 -6606
STT3A 3820 5008
STX17 -4480 -10772
STX5 3566 8258
SYVN1 734 2029
TBC1D20 -6556 3818
TFG 8930 6725
TGFA 7935 9686
TMED10 35 2168
TMED2 6426 6360
TMED3 -2098 4751
TMED7 9038 7918
TMED9 917 9007
TMEM115 31 6881
TRAPPC1 5277 9110
TRAPPC10 -10478 -2812
TRAPPC2 -8890 -5344
TRAPPC2L -350 -932
TRAPPC3 6827 7922
TRAPPC4 -7161 -2663
TRAPPC5 4081 6280
TRAPPC6A -7665 -10218
TRAPPC6B 6230 4019
TRAPPC9 921 7473
TRIM13 -969 -1503
TSTA3 6432 6332
UAP1 -10828 -9681
UBA52 -1875 3023
UBB 8251 6157
UBC -1915 5825
UBXN1 -7382 5180
UGGT1 2808 6596
UGGT2 7847 4069
USO1 6916 3905
VCP 3600 7754
YKT6 -3724 6818



Scavenging of heme from plasma

Scavenging of heme from plasma
metric value
setSize 70
pMANOVA 2.16e-17
p.adjustMANOVA 1.73e-15
s.dist 0.376
s.low.CRP 0.25
s.high.CRP -0.28
p.low.CRP 0.000292
p.high.CRP 5.05e-05




Top 20 genes
Gene low CRP high CRP
JCHAIN 4874 -8700
IGKV3-11 5548 -7167
IGKV1-33 5955 -6384
IGKV1-16 6217 -5451
IGKV1-5 6127 -5162
IGLV5-45 4194 -7364
IGHV3-23 6032 -5092
IGHA1 4926 -5918
IGKV2-30 5205 -5349
IGLV1-44 4742 -5791
IGHV4-59 4532 -5870
IGLV2-8 4818 -5256
IGHV4-39 3786 -6542
IGLV3-19 4006 -5611
IGHV1-2 5956 -3146
IGKV3-20 3704 -5021
IGKC 2773 -6437
IGLV1-36 3522 -5030
IGHV3-11 3518 -4591
IGHV3-7 4185 -3630

Click HERE to show all gene set members

All member genes
low CRP high CRP
ALB 1254 3551
APOL1 -7427 -4732
CD163 10038 10038
HBA1 10009 8734
HBB 10013 8750
HP 9925 10000
HPX 477 -1968
IGHA1 4926 -5918
IGHA2 2335 -2345
IGHV1-2 5956 -3146
IGHV1-46 3766 -2976
IGHV1-69 2354 -2328
IGHV2-5 4451 -1972
IGHV2-70 -3315 -2159
IGHV3-11 3518 -4591
IGHV3-13 799 -2451
IGHV3-23 6032 -5092
IGHV3-30 2500 -5193
IGHV3-33 98 -4138
IGHV3-48 3183 -4340
IGHV3-53 3131 -1786
IGHV3-7 4185 -3630
IGHV4-34 1144 -4007
IGHV4-39 3786 -6542
IGHV4-59 4532 -5870
IGKC 2773 -6437
IGKV1-12 725 -6674
IGKV1-16 6217 -5451
IGKV1-17 -241 -2794
IGKV1-33 5955 -6384
IGKV1-5 6127 -5162
IGKV1D-39 5018 -2677
IGKV2-28 1440 -6662
IGKV2-30 5205 -5349
IGKV2D-28 -7224 -2947
IGKV3-11 5548 -7167
IGKV3-15 3174 -4687
IGKV3-20 3704 -5021
IGKV3D-20 -1830 -4618
IGKV4-1 2812 -4988
IGKV5-2 5226 -2682
IGLC1 -2813 -6176
IGLC2 -258 -6539
IGLC3 -2958 -4378
IGLC7 -3403 -4490
IGLV1-36 3522 -5030
IGLV1-40 163 -5497
IGLV1-44 4742 -5791
IGLV1-47 231 -6633
IGLV1-51 1708 -6601
IGLV10-54 -5422 316
IGLV2-11 870 -3205
IGLV2-14 -5127 -8197
IGLV2-18 2015 -2963
IGLV2-23 2029 -4201
IGLV2-8 4818 -5256
IGLV3-1 -96 -5140
IGLV3-12 -7299 -6816
IGLV3-19 4006 -5611
IGLV3-21 -975 -6062
IGLV3-25 -942 -5485
IGLV3-27 -5365 -4834
IGLV4-69 1344 -2261
IGLV5-45 4194 -7364
IGLV6-57 1834 -5837
IGLV7-43 4854 -2823
IGLV7-46 2445 -3619
IGLV8-61 -3989 -5208
JCHAIN 4874 -8700
LRP1 9226 9878



Response to elevated platelet cytosolic Ca2+

Response to elevated platelet cytosolic Ca2+
metric value
setSize 108
pMANOVA 8.5e-17
p.adjustMANOVA 6.44e-15
s.dist 0.599
s.low.CRP 0.38
s.high.CRP 0.463
p.low.CRP 9.02e-12
p.high.CRP 8.21e-17




Top 20 genes
Gene low CRP high CRP
F5 10084 10070
CYB5R1 9974 10035
CD36 10064 9814
APLP2 9601 10056
CLU 9512 10102
LHFPL2 9961 9629
QSOX1 9451 10048
ALDOA 9625 9857
APP 9951 9504
ACTN1 9831 9585
SERPINA1 9571 9817
FERMT3 9331 9956
ITGA2B 9720 9409
STXBP2 9017 9835
CD63 8797 10079
HGF 9753 8929
LAMP2 9608 8999
SRGN 9312 9121
F13A1 9955 8516
TOR4A 8491 9893

Click HERE to show all gene set members

All member genes
low CRP high CRP
A1BG 5929 5909
A2M -7113 -9795
ABCC4 8425 7787
ACTN1 9831 9585
ACTN4 -8606 8331
ALB 1254 3551
ALDOA 9625 9857
ANXA5 8914 8338
APLP2 9601 10056
APOOL 5334 925
APP 9951 9504
BRPF3 -9358 -1215
CALM1 -6645 1321
CALU 9106 7766
CAP1 8192 8530
CD109 5339 4477
CD36 10064 9814
CD63 8797 10079
CD9 9005 4476
CDC37L1 -228 -8385
CFD 2998 2390
CFL1 5851 9242
CHID1 -2802 4694
CLEC3B 8445 9345
CLU 9512 10102
CTSW -11085 -6320
CYB5R1 9974 10035
ECM1 6130 5365
EGF 9244 8355
ENDOD1 4364 3483
F13A1 9955 8516
F5 10084 10070
F8 7498 7167
FAM3C -7438 -8642
FERMT3 9331 9956
FLNA -8145 4196
FN1 10003 6211
GAS6 6462 9517
GTPBP2 1314 8197
HABP4 -5318 -10970
HGF 9753 8929
HSPA5 8070 6713
ITGA2B 9720 9409
ITGB3 9450 8690
ITIH3 598 -3824
ITIH4 -5812 -4898
LAMP2 9608 8999
LGALS3BP -5766 -10889
LHFPL2 9961 9629
LY6G6F 8519 8935
MAGED2 -7650 1289
MANF 2669 2863
MMRN1 8473 8262
NHLRC2 -1125 -8298
OLA1 8253 3668
ORM1 8665 8363
ORM2 -4938 149
PCYOX1L 1442 -1806
PDGFA 6115 5392
PDGFB -4645 -8897
PECAM1 8136 8308
PF4 6097 6609
PFN1 -5663 7801
PHACTR2 4871 5821
PLEK -7872 4766
PLG 1277 -2998
PPBP 7528 6376
PPIA -7248 -2108
PRKCA 2473 1229
PRKCB 5395 8378
PROS1 9065 7937
PSAP 7519 7770
QSOX1 9451 10048
RAB27B -847 4689
SCCPDH 8175 8195
SELENOP -361 -9226
SELP 9499 8610
SERPINA1 9571 9817
SERPINE1 7839 8101
SERPINF2 -7666 -3830
SERPING1 -6329 -10968
SOD1 -1389 -3334
SPARC 9073 7195
SRGN 9312 9121
STX4 -7285 5736
STXBP2 9017 9835
STXBP3 9347 6785
SYTL4 8201 9013
TAGLN2 7953 7664
TEX264 -10026 -2139
TF 1794 1244
TGFB1 -2566 6745
TGFB2 -8959 -4641
TGFB3 -7945 -6237
THBS1 1778 8102
TIMP1 6136 9944
TLN1 7865 9661
TMSB4X 6454 6825
TMX3 5784 -2953
TOR4A 8491 9893
TTN 1884 1350
TUBA4A 652 7677
VCL 7488 7955
VEGFA 8464 8215
VEGFB -7685 -5963
VTI1B 9177 8851
VWF 6949 7780
WDR1 -1705 8441



Toll-like Receptor Cascades

Toll-like Receptor Cascades
metric value
setSize 143
pMANOVA 4.51e-16
p.adjustMANOVA 3.11e-14
s.dist 0.495
s.low.CRP 0.286
s.high.CRP 0.404
p.low.CRP 3.68e-09
p.high.CRP 6.79e-17




Top 20 genes
Gene low CRP high CRP
S100A9 10110 10116
S100A12 10088 10121
S100A8 10041 10093
ITGAM 9846 10065
CD36 10064 9814
TLR8 9957 9871
CTSB 9526 10083
DUSP3 9937 9647
NKIRAS2 9581 9936
MAPK14 9907 9606
TLR5 9746 9721
APP 9951 9504
UBE2D1 9825 9491
IRAK3 9660 9553
CD14 9551 9658
TLR4 9494 9617
TLR2 9930 9118
MAP2K1 9163 9879
MAP2K6 9435 9577
TLR6 9634 9209

Click HERE to show all gene set members

All member genes
low CRP high CRP
AGER -1839 3181
APP 9951 9504
ATF1 7833 5463
ATF2 7002 164
BIRC2 8079 3449
BIRC3 -2270 -11079
BPI 9613 4607
BTK 7623 7870
BTRC -6845 -441
CASP8 -10359 -8523
CD14 9551 9658
CD180 -749 281
CD36 10064 9814
CHUK 9198 7663
CNPY3 7458 8402
CREB1 4878 -3476
CTSB 9526 10083
CTSK 7647 4123
CTSL -5538 5895
CTSS 9854 7280
CTSV -1271 -2930
CUL1 -2085 -10951
DNM1 6883 3239
DNM2 -6816 8202
DNM3 7927 7198
DUSP3 9937 9647
DUSP4 -6630 -4192
DUSP6 7994 2589
DUSP7 -4748 387
ECSIT 4110 5590
EEA1 8100 3526
ELK1 -355 3195
FADD -3611 7477
FBXW11 4585 7364
FOS 6663 6569
HMGB1 3876 -968
HSP90B1 7042 372
IKBKB -5276 -2118
IKBKE 387 6793
IKBKG -3058 7903
IRAK1 2444 7601
IRAK2 -11058 -2404
IRAK3 9660 9553
IRF3 -6904 -7151
IRF7 -8896 -5369
ITGAM 9846 10065
ITGB2 8042 10007
JUN 2838 4810
LGMN -3548 -2820
LY86 9457 6684
LY96 9529 8995
MAP2K1 9163 9879
MAP2K3 8978 9308
MAP2K4 6895 7431
MAP2K6 9435 9577
MAP2K7 -2754 4813
MAP3K1 5466 5938
MAP3K7 1546 4274
MAP3K8 -7139 8928
MAPK1 1052 9260
MAPK10 6734 3872
MAPK11 7257 1843
MAPK14 9907 9606
MAPK3 8931 9626
MAPK7 -10125 5069
MAPK8 -1061 -9914
MAPK9 -6530 -1870
MAPKAPK2 -10572 6892
MAPKAPK3 7493 9250
MEF2A 9000 8162
MEF2C 6943 -2868
MYD88 8651 8344
NFKB1 7857 6377
NFKB2 3069 -1167
NFKBIA 6855 7374
NFKBIB -9679 5479
NKIRAS1 2619 689
NKIRAS2 9581 9936
NOD1 -10930 -10348
NOD2 9408 8613
PELI1 9064 5690
PELI2 9242 9060
PELI3 5708 8764
PIK3C3 6605 573
PIK3R4 -267 -2209
PLCG2 -4618 6826
PPP2CA 8810 8328
PPP2CB 8482 7631
PPP2R1A -3087 6994
PPP2R1B 2503 437
PPP2R5D -6508 4985
PTPN11 4691 6614
PTPN4 -10946 -10632
RBSN -7312 339
RELA -7305 2739
RIPK1 -10879 -4699
RIPK2 1665 2297
RIPK3 -5133 7348
RPS27A -3555 -7070
RPS6KA1 -105 9153
RPS6KA2 -5428 3882
RPS6KA3 2859 3437
RPS6KA5 -3980 -11177
S100A1 -7792 -5913
S100A12 10088 10121
S100A8 10041 10093
S100A9 10110 10116
S100B -8212 -1271
SARM1 -10456 -10950
SIGIRR -9900 -8613
SKP1 8120 2700
SOCS1 -219 6051
TAB1 6623 5746
TAB2 9197 5726
TAB3 3912 3647
TANK 8959 7267
TBK1 5846 2973
TICAM1 6742 6552
TICAM2 9182 4768
TIRAP 262 7730
TLR1 9828 8868
TLR10 -122 -3607
TLR2 9930 9118
TLR3 -9935 -9836
TLR4 9494 9617
TLR5 9746 9721
TLR6 9634 9209
TLR7 8636 -4675
TLR8 9957 9871
TLR9 -10413 -138
TNIP2 -1490 7359
TRAF3 2694 -5265
TRAF6 -1767 2089
UBA52 -1875 3023
UBB 8251 6157
UBC -1915 5825
UBE2D1 9825 9491
UBE2D2 2673 5593
UBE2D3 9443 8783
UBE2N 4087 2050
UBE2V1 6665 5995
UNC93B1 -1309 6224
VRK3 -7245 5798



Platelet degranulation

Platelet degranulation
metric value
setSize 104
pMANOVA 4.56e-16
p.adjustMANOVA 3.11e-14
s.dist 0.598
s.low.CRP 0.383
s.high.CRP 0.459
p.low.CRP 1.42e-11
p.high.CRP 5.6e-16




Top 20 genes
Gene low CRP high CRP
F5 10084 10070
CYB5R1 9974 10035
CD36 10064 9814
APLP2 9601 10056
CLU 9512 10102
LHFPL2 9961 9629
QSOX1 9451 10048
ALDOA 9625 9857
APP 9951 9504
ACTN1 9831 9585
SERPINA1 9571 9817
FERMT3 9331 9956
ITGA2B 9720 9409
STXBP2 9017 9835
CD63 8797 10079
HGF 9753 8929
LAMP2 9608 8999
SRGN 9312 9121
F13A1 9955 8516
TOR4A 8491 9893

Click HERE to show all gene set members

All member genes
low CRP high CRP
A1BG 5929 5909
A2M -7113 -9795
ABCC4 8425 7787
ACTN1 9831 9585
ACTN4 -8606 8331
ALB 1254 3551
ALDOA 9625 9857
ANXA5 8914 8338
APLP2 9601 10056
APOOL 5334 925
APP 9951 9504
BRPF3 -9358 -1215
CALM1 -6645 1321
CALU 9106 7766
CAP1 8192 8530
CD109 5339 4477
CD36 10064 9814
CD63 8797 10079
CD9 9005 4476
CDC37L1 -228 -8385
CFD 2998 2390
CFL1 5851 9242
CHID1 -2802 4694
CLEC3B 8445 9345
CLU 9512 10102
CTSW -11085 -6320
CYB5R1 9974 10035
ECM1 6130 5365
EGF 9244 8355
ENDOD1 4364 3483
F13A1 9955 8516
F5 10084 10070
F8 7498 7167
FAM3C -7438 -8642
FERMT3 9331 9956
FLNA -8145 4196
FN1 10003 6211
GAS6 6462 9517
GTPBP2 1314 8197
HABP4 -5318 -10970
HGF 9753 8929
HSPA5 8070 6713
ITGA2B 9720 9409
ITGB3 9450 8690
ITIH3 598 -3824
ITIH4 -5812 -4898
LAMP2 9608 8999
LGALS3BP -5766 -10889
LHFPL2 9961 9629
LY6G6F 8519 8935
MAGED2 -7650 1289
MANF 2669 2863
MMRN1 8473 8262
NHLRC2 -1125 -8298
OLA1 8253 3668
ORM1 8665 8363
ORM2 -4938 149
PCYOX1L 1442 -1806
PDGFA 6115 5392
PDGFB -4645 -8897
PECAM1 8136 8308
PF4 6097 6609
PFN1 -5663 7801
PHACTR2 4871 5821
PLEK -7872 4766
PLG 1277 -2998
PPBP 7528 6376
PPIA -7248 -2108
PROS1 9065 7937
PSAP 7519 7770
QSOX1 9451 10048
RAB27B -847 4689
SCCPDH 8175 8195
SELENOP -361 -9226
SELP 9499 8610
SERPINA1 9571 9817
SERPINE1 7839 8101
SERPINF2 -7666 -3830
SERPING1 -6329 -10968
SOD1 -1389 -3334
SPARC 9073 7195
SRGN 9312 9121
STXBP2 9017 9835
SYTL4 8201 9013
TAGLN2 7953 7664
TEX264 -10026 -2139
TF 1794 1244
TGFB1 -2566 6745
TGFB2 -8959 -4641
TGFB3 -7945 -6237
THBS1 1778 8102
TIMP1 6136 9944
TLN1 7865 9661
TMSB4X 6454 6825
TMX3 5784 -2953
TOR4A 8491 9893
TTN 1884 1350
TUBA4A 652 7677
VCL 7488 7955
VEGFA 8464 8215
VEGFB -7685 -5963
VTI1B 9177 8851
VWF 6949 7780
WDR1 -1705 8441



Diseases of signal transduction by growth factor receptors and second messengers

Diseases of signal transduction by growth factor receptors and second messengers
metric value
setSize 339
pMANOVA 7.52e-16
p.adjustMANOVA 4.88e-14
s.dist 0.3
s.low.CRP 0.145
s.high.CRP 0.263
p.low.CRP 4.51e-06
p.high.CRP 8.91e-17




Top 20 genes
Gene low CRP high CRP
FZD5 10104 10128
GRB2 9631 9985
NCSTN 9503 9869
QKI 9569 9736
ITGA2B 9720 9409
PIK3CB 9838 9248
MAP2K1 9163 9879
MAML3 9463 9534
KL 9145 9846
PAPSS1 9369 9581
MARK3 9434 9486
KREMEN1 8950 9970
CUX1 8954 9964
FKBP1A 9920 8990
HDAC4 9329 9546
ADAM10 9314 9481
RBPJ 9652 9125
HGF 9753 8929
RAC1 9052 9614
AGTRAP 9096 9556

Click HERE to show all gene set members

All member genes
low CRP high CRP
ADAM10 9314 9481
ADAM17 8058 9718
AGGF1 6052 6971
AGK -9841 -11206
AGTRAP 9096 9556
AKAP9 2530 -6270
AKT1 -4794 6231
AKT1S1 8045 8241
AKT2 -8391 5504
AKT3 -9616 -10833
AMER1 -9251 -9464
AP3B1 8649 9145
APBB1IP 9427 9201
APC 3083 3959
APH1A -3379 6321
APH1B 6306 6678
ARAF -5280 5379
AREG 4465 7165
ARRB1 -4581 4541
ARRB2 7827 9274
ATG7 9062 8455
AXIN1 -10901 -2157
BAD 1009 8765
BAG4 9013 9084
BCL2L11 8059 7998
BCR -10286 261
BIN2 -7555 7878
BRAF 276 2552
BRAP 7133 5359
CALM1 -6645 1321
CAMK2D -9328 -10857
CAMK2G -646 3153
CASP9 5303 9133
CBL 6620 8302
CCNC 7860 -2135
CD19 -2992 -2929
CD28 -2082 -11208
CD80 -2297 -7693
CD86 5511 -1419
CDC37 -4604 7006
CDK8 -3688 1375
CDKN1A 3621 5190
CDKN1B -9926 -2672
CHUK 9198 7663
CLCN6 4520 2014
CNKSR1 2877 -8713
CNKSR2 786 -5158
CNTRL 120 -7228
CPSF6 4443 -8013
CREB1 4878 -3476
CREBBP -4951 6023
CSK -5436 7707
CSNK1A1 8062 8483
CTBP1 -10319 2597
CTBP2 -8332 7583
CTNNB1 3201 7613
CUL1 -2085 -10951
CUX1 8954 9964
DERL2 4947 3337
DLL1 -10099 -11006
DUSP10 -2707 823
DUSP16 -4867 -5937
DUSP6 7994 2589
DUSP7 -4748 387
DUSP8 -10417 -9519
EGF 9244 8355
EP300 4311 7552
ERBB2 -11251 -9287
ERBB3 3021 -1481
ERBIN 2164 -118
EREG -837 3226
ERLEC1 157 2344
ERLIN2 8632 9807
ESR1 -6046 -8495
ESR2 -4206 -10115
ETV6 6776 5766
FAM114A2 5550 5072
FAM131B -7635 2425
FBXW7 -5277 -3657
FGF2 5967 3177
FGF22 -5885 -8493
FGF23 -3924 -7953
FGF7 158 -5338
FGF9 -8383 -6950
FGFR1 -8719 -822
FGFR1OP2 9863 6214
FGFR2 -10068 -10229
FGFR4 -1760 -2742
FIP1L1 -8488 -1467
FKBP1A 9920 8990
FN1 10003 6211
FOXO1 -4402 -9319
FOXO3 8202 9854
FOXO4 -615 8296
FOXO6 -9309 -1189
FRS2 1765 -3137
FXR1 7067 5963
FYN -10878 -6729
FZD4 -10858 -7985
FZD5 10104 10128
FZD6 -304 -7933
FZD8 -9255 -2577
GAB1 7926 5272
GAB2 7546 9347
GOLGA4 -783 -4010
GRB2 9631 9985
GSK3A 5279 8683
GSK3B 6119 7526
GTF2F1 -3109 7342
GTF2F2 4728 6017
HBEGF 5089 5189
HDAC1 -3835 3708
HDAC10 -489 4165
HDAC11 804 5759
HDAC2 8973 3999
HDAC3 1719 6319
HDAC4 9329 9546
HDAC5 3359 5480
HDAC6 -7766 -5123
HDAC7 4750 7247
HDAC8 3980 4023
HDAC9 6738 -815
HES1 -10141 -3420
HGF 9753 8929
HHAT -6205 -8610
HRAS -2248 -1932
HSP90AA1 5309 410
ICOS 1302 -10781
IQGAP1 7310 9366
IRS1 6140 8
IRS2 8141 9618
ITGA2B 9720 9409
ITGB3 9450 8690
JAG1 9550 8956
JAG2 -10015 -8085
JAK2 7618 374
KANK1 3022 -7617
KAT2A -6742 -10405
KAT2B 116 -1532
KDM7A 8052 6799
KIAA1549 7040 2139
KIT -10872 -8011
KL 9145 9846
KRAS 3789 4070
KREMEN1 8950 9970
KREMEN2 -6004 4016
KSR1 326 5540
KSR2 -3767 -1942
LCK -10358 -10719
LMNA 1706 5027
LRP5 5683 4611
LRP6 3999 -1401
LRRFIP1 6242 6811
LYN 7575 8379
MAML1 -81 7084
MAML2 3788 -1483
MAML3 9463 9534
MAMLD1 -532 -6686
MAP2K1 9163 9879
MAP2K2 185 8452
MAP3K11 6025 8985
MAPK1 1052 9260
MAPK3 8931 9626
MAPKAP1 2536 5925
MARK3 9434 9486
MDM2 7204 3892
MIB1 3219 -3926
MIB2 -10461 -7734
MLST8 -3991 2978
MPRIP -9471 -9503
MRAS -10710 298
MTOR -10419 -3248
MYC 8429 -2186
MYO18A -8578 2221
NCBP1 1766 -6055
NCBP2 3719 -10143
NCOR1 3309 7790
NCOR2 4843 9646
NCSTN 9503 9869
NEURL1 -11174 -6488
NEURL1B -9540 2352
NF1 -1234 4267
NOTCH1 -6446 6708
NR4A1 -7773 -6467
NRAS 7321 4878
NRG1 8713 914
NRG4 1196 -3291
OS9 8889 9708
PAPSS1 9369 9581
PDGFA 6115 5392
PDGFB -4645 -8897
PDGFRA 2481 6753
PDGFRB -11134 -5992
PDPK1 2392 7816
PEBP1 -8004 -10339
PHB -4398 564
PIK3AP1 6149 8581
PIK3CA 6889 4182
PIK3CB 9838 9248
PIK3CD 82 7288
PIK3R1 -7197 -8942
PIK3R2 2459 5820
PIK3R3 -11107 -8159
PLCG1 -6360 -11043
POLR2A -8726 2901
POLR2B -1034 188
POLR2C -2183 3527
POLR2D 3401 -4083
POLR2E 6766 8343
POLR2F -2307 6746
POLR2G -5778 6576
POLR2H 653 -2264
POLR2I -2123 2695
POLR2J 4448 7822
POLR2K 1881 -1885
POLR2L 126 7246
PORCN -9834 -6886
PPP1CB 8657 6666
PPP1CC 9200 4868
PPP2CA 8810 8328
PPP2CB 8482 7631
PPP2R1A -3087 6994
PPP2R1B 2503 437
PPP2R5A -903 6957
PPP2R5B 5288 7952
PPP2R5C -10420 -7112
PPP2R5D -6508 4985
PPP2R5E 715 540
PRR5 -11173 -8620
PSEN1 7889 8878
PSEN2 -5169 -5867
PSENEN 2692 7551
PSMA1 8278 7406
PSMA2 5830 5666
PSMA3 4646 -7621
PSMA4 3950 -1036
PSMA5 -2119 -3983
PSMA6 6893 5865
PSMA7 3550 8554
PSMB1 3915 4224
PSMB10 -7878 -1272
PSMB2 2664 4928
PSMB3 4971 8382
PSMB4 -3175 4911
PSMB5 6561 9138
PSMB6 1312 8784
PSMB7 8034 9051
PSMB8 -4481 75
PSMB9 -9105 -10433
PSMC1 6759 7782
PSMC2 -2524 4517
PSMC3 -4971 4984
PSMC4 -10757 -336
PSMC5 -3424 2764
PSMC6 8812 6000
PSMD1 7679 7587
PSMD10 2067 2450
PSMD11 6914 6824
PSMD12 9011 5710
PSMD13 3157 7205
PSMD14 2891 3041
PSMD2 4352 8396
PSMD3 -2243 6367
PSMD4 6858 9449
PSMD5 2770 4781
PSMD6 8841 8304
PSMD7 6534 6147
PSMD8 739 7117
PSMD9 3580 9001
PSME1 -7256 -7913
PSME2 -5548 -10355
PSME3 9120 8239
PSME4 -5205 -3127
PSMF1 6709 6770
PTEN 9191 8752
PTPN11 4691 6614
PTPN12 7921 9275
QKI 9569 9736
RAC1 9052 9614
RAC2 -7677 6828
RAF1 8477 8327
RAP1A 8688 6973
RAP1B -2703 4941
RBPJ 9652 9125
RBX1 1418 4877
RHOG 7549 9255
RICTOR -3978 -9726
RNF43 -9524 -11210
RPS27A -3555 -7070
RPS6KB2 -4855 4416
SEL1L 7157 7252
SEM1 993 5942
SHC1 -3416 5815
SHOC2 8573 7262
SKP1 8120 2700
SMAD2 5238 5871
SMAD3 -10084 -10081
SMAD4 -3009 -6696
SND1 -82 6307
SNW1 6824 5161
SOS1 3534 -7412
SPRED1 -7983 -6504
SPRED2 -404 8453
SPRED3 -6894 -4695
SRC -6857 -7229
STAT1 -7385 -11118
STAT3 8512 8606
STAT5A 6437 7973
STAT5B 4758 7433
STRN 215 5171
SYVN1 734 2029
TBL1X 8359 8499
TBL1XR1 4714 4779
TCF7L2 -10402 -1302
TENT4A -6785 -10789
TGFA 7935 9686
TGFB1 -2566 6745
TGFBR1 -7960 3224
TGFBR2 -5037 6173
TLN1 7865 9661
TNKS -7769 -6024
TNKS2 604 1179
TRAK1 4501 6029
TRAT1 5825 -10715
TRIM24 7340 2782
TSC2 -4535 2859
UBA52 -1875 3023
UBB 8251 6157
UBC -1915 5825
VAV1 5553 8731
VCL 7488 7955
VCP 3600 7754
VWF 6949 7780
WDR48 -7124 -9778
YES1 -11138 -8566
YWHAB 8274 6101
ZC3HAV1 -5479 -8568
ZFYVE9 -4592 -7944
ZMYM2 5946 3690



CD22 mediated BCR regulation

CD22 mediated BCR regulation
metric value
setSize 58
pMANOVA 1.55e-15
p.adjustMANOVA 9.58e-14
s.dist 0.4
s.low.CRP 0.197
s.high.CRP -0.348
p.low.CRP 0.00956
p.high.CRP 4.59e-06




Top 20 genes
Gene low CRP high CRP
IGKV3-11 5548 -7167
IGKV1-33 5955 -6384
IGKV1-16 6217 -5451
IGKV1-5 6127 -5162
IGHV3-23 6032 -5092
IGKV2-30 5205 -5349
IGLV1-44 4742 -5791
IGHV4-59 4532 -5870
IGLV2-8 4818 -5256
IGHV4-39 3786 -6542
IGLV3-19 4006 -5611
IGHV1-2 5956 -3146
IGKV3-20 3704 -5021
IGKC 2773 -6437
IGHV3-11 3518 -4591
IGHV3-7 4185 -3630
IGKV3-15 3174 -4687
IGKV4-1 2812 -4988
IGKV5-2 5226 -2682
IGHV3-48 3183 -4340

Click HERE to show all gene set members

All member genes
low CRP high CRP
CD22 -3032 -4243
CD79A -3264 -4267
CD79B -6240 -6157
IGHD -2028 -4193
IGHM 1890 -2470
IGHV1-2 5956 -3146
IGHV1-46 3766 -2976
IGHV1-69 2354 -2328
IGHV2-5 4451 -1972
IGHV2-70 -3315 -2159
IGHV3-11 3518 -4591
IGHV3-13 799 -2451
IGHV3-23 6032 -5092
IGHV3-30 2500 -5193
IGHV3-33 98 -4138
IGHV3-48 3183 -4340
IGHV3-53 3131 -1786
IGHV3-7 4185 -3630
IGHV4-34 1144 -4007
IGHV4-39 3786 -6542
IGHV4-59 4532 -5870
IGKC 2773 -6437
IGKV1-12 725 -6674
IGKV1-16 6217 -5451
IGKV1-17 -241 -2794
IGKV1-33 5955 -6384
IGKV1-5 6127 -5162
IGKV1D-39 5018 -2677
IGKV2-28 1440 -6662
IGKV2-30 5205 -5349
IGKV2D-28 -7224 -2947
IGKV3-11 5548 -7167
IGKV3-15 3174 -4687
IGKV3-20 3704 -5021
IGKV3D-20 -1830 -4618
IGKV4-1 2812 -4988
IGKV5-2 5226 -2682
IGLC1 -2813 -6176
IGLC2 -258 -6539
IGLC3 -2958 -4378
IGLC7 -3403 -4490
IGLV1-40 163 -5497
IGLV1-44 4742 -5791
IGLV1-47 231 -6633
IGLV1-51 1708 -6601
IGLV2-11 870 -3205
IGLV2-14 -5127 -8197
IGLV2-23 2029 -4201
IGLV2-8 4818 -5256
IGLV3-1 -96 -5140
IGLV3-19 4006 -5611
IGLV3-21 -975 -6062
IGLV3-25 -942 -5485
IGLV3-27 -5365 -4834
IGLV6-57 1834 -5837
IGLV7-43 4854 -2823
LYN 7575 8379
PTPN6 -691 7862



Creation of C4 and C2 activators

Creation of C4 and C2 activators
metric value
setSize 70
pMANOVA 4.1e-15
p.adjustMANOVA 2.43e-13
s.dist 0.359
s.low.CRP 0.174
s.high.CRP -0.314
p.low.CRP 0.0118
p.high.CRP 5.41e-06




Top 20 genes
Gene low CRP high CRP
IGKV3-11 5548 -7167
IGKV1-33 5955 -6384
IGKV1-16 6217 -5451
IGKV1-5 6127 -5162
IGLV5-45 4194 -7364
IGHV3-23 6032 -5092
IGKV2-30 5205 -5349
IGLV1-44 4742 -5791
IGHV4-59 4532 -5870
IGLV2-8 4818 -5256
IGHV4-39 3786 -6542
IGLV3-19 4006 -5611
IGHV1-2 5956 -3146
IGKV3-20 3704 -5021
IGKC 2773 -6437
IGLV1-36 3522 -5030
IGHV3-11 3518 -4591
IGHV3-7 4185 -3630
IGKV3-15 3174 -4687
MASP2 2089 -6883

Click HERE to show all gene set members

All member genes
low CRP high CRP
C1QA -49 7890
C1QB 6746 8930
C1QC 7805 9340
C1R -10393 -4020
C1S -6159 552
FCN1 9889 9103
IGHG1 -1124 -7111
IGHG2 -5587 -6004
IGHG3 -507 -4089
IGHG4 -4038 -5940
IGHV1-2 5956 -3146
IGHV1-46 3766 -2976
IGHV1-69 2354 -2328
IGHV2-5 4451 -1972
IGHV2-70 -3315 -2159
IGHV3-11 3518 -4591
IGHV3-13 799 -2451
IGHV3-23 6032 -5092
IGHV3-30 2500 -5193
IGHV3-33 98 -4138
IGHV3-48 3183 -4340
IGHV3-53 3131 -1786
IGHV3-7 4185 -3630
IGHV4-34 1144 -4007
IGHV4-39 3786 -6542
IGHV4-59 4532 -5870
IGKC 2773 -6437
IGKV1-12 725 -6674
IGKV1-16 6217 -5451
IGKV1-17 -241 -2794
IGKV1-33 5955 -6384
IGKV1-5 6127 -5162
IGKV1D-39 5018 -2677
IGKV2-28 1440 -6662
IGKV2-30 5205 -5349
IGKV2D-28 -7224 -2947
IGKV3-11 5548 -7167
IGKV3-15 3174 -4687
IGKV3-20 3704 -5021
IGKV3D-20 -1830 -4618
IGKV4-1 2812 -4988
IGKV5-2 5226 -2682
IGLC1 -2813 -6176
IGLC2 -258 -6539
IGLC3 -2958 -4378
IGLC7 -3403 -4490
IGLV1-36 3522 -5030
IGLV1-40 163 -5497
IGLV1-44 4742 -5791
IGLV1-47 231 -6633
IGLV1-51 1708 -6601
IGLV10-54 -5422 316
IGLV2-11 870 -3205
IGLV2-14 -5127 -8197
IGLV2-18 2015 -2963
IGLV2-23 2029 -4201
IGLV2-8 4818 -5256
IGLV3-1 -96 -5140
IGLV3-12 -7299 -6816
IGLV3-19 4006 -5611
IGLV3-21 -975 -6062
IGLV3-25 -942 -5485
IGLV3-27 -5365 -4834
IGLV4-69 1344 -2261
IGLV5-45 4194 -7364
IGLV6-57 1834 -5837
IGLV7-43 4854 -2823
IGLV7-46 2445 -3619
IGLV8-61 -3989 -5208
MASP2 2089 -6883



ER to Golgi Anterograde Transport

ER to Golgi Anterograde Transport
metric value
setSize 129
pMANOVA 4.52e-15
p.adjustMANOVA 2.51e-13
s.dist 0.48
s.low.CRP 0.242
s.high.CRP 0.414
p.low.CRP 1.99e-06
p.high.CRP 4.59e-16




Top 20 genes
Gene low CRP high CRP
F5 10084 10070
SERPINA1 9571 9817
ARF4 9859 9444
SPTB 9958 9302
KDELR1 9552 9681
CD55 9326 9842
RAB1A 9700 9407
CTSZ 8972 9860
NSF 8895 9680
DCTN2 8504 10012
ANK1 9797 8626
ARF1 8465 9910
CAPZA2 9698 8474
TGFA 7935 9686
DCTN4 7967 9572
CAPZA1 8666 8511
COPA 7617 9591
TMED7 9038 7918
SEC24D 8017 8795
COPB2 8531 8034

Click HERE to show all gene set members

All member genes
low CRP high CRP
ACTR10 8589 7569
ACTR1A -2833 8680
ANK1 9797 8626
ANK3 3262 -7407
ANKRD28 -5795 -3898
ARCN1 4082 6402
AREG 4465 7165
ARF1 8465 9910
ARF3 5651 9049
ARF4 9859 9444
ARF5 5736 9180
ARFGAP1 -6136 2991
ARFGAP2 -8987 2096
ARFGAP3 -6040 5157
BET1 7030 -4395
BET1L -7832 -2582
CAPZA1 8666 8511
CAPZA2 9698 8474
CAPZB 6100 8926
CD55 9326 9842
CD59 4075 5772
CNIH1 9316 7116
CNIH2 701 601
CNIH3 -8173 -6989
COG1 -10399 -10838
COG2 -1210 -5915
COG3 3891 -5333
COG4 -4813 2002
COG5 1617 -3368
COG6 1512 -6280
COG7 2191 6149
COG8 -2814 2839
COL7A1 3993 7683
COPA 7617 9591
COPB1 8213 7283
COPB2 8531 8034
COPE 365 8719
COPG1 2542 9195
COPG2 7905 8313
COPZ1 2549 5017
COPZ2 -9229 -9247
CSNK1D -10030 6117
CTSC -7528 5285
CTSZ 8972 9860
DCTN1 -5984 7873
DCTN2 8504 10012
DCTN3 325 7904
DCTN4 7967 9572
DCTN5 -7505 664
DCTN6 7871 7759
DYNC1H1 -8881 -2533
DYNC1I1 7141 2722
DYNC1I2 8160 8196
DYNC1LI1 7894 6997
DYNC1LI2 3494 5636
DYNLL1 6026 6499
DYNLL2 -6325 -225
F5 10084 10070
F8 7498 7167
GBF1 -8933 1807
GOLGA2 -878 8019
GOLGB1 -242 -5768
GORASP1 7651 6560
GOSR1 -4021 2971
GOSR2 -2437 1468
KDELR1 9552 9681
KDELR2 8771 7531
KDELR3 2255 -3318
LMAN1 -1255 -10522
LMAN2 2397 8522
LMAN2L 7675 6680
MCFD2 7963 7485
MIA2 6640 5566
MIA3 3397 -6425
NAPA -2447 3305
NAPB -291 -2004
NAPG 7409 3591
NSF 8895 9680
PPP6C 8559 6316
PPP6R1 -5320 7658
PPP6R3 3008 3925
PREB -1638 8142
RAB1A 9700 9407
RAB1B 5676 9455
SAR1B 8795 5984
SCFD1 4551 3924
SEC13 2125 6861
SEC16A -2929 6748
SEC16B -1454 1213
SEC22A 374 -4424
SEC22B 8663 4943
SEC22C -2377 -1611
SEC23A 8776 6905
SEC23IP 5231 -574
SEC24A 8318 7788
SEC24B 1663 5398
SEC24C -9662 3561
SEC24D 8017 8795
SEC31A 1743 2474
SERPINA1 9571 9817
SPTA1 9470 6216
SPTAN1 -10174 -8889
SPTB 9958 9302
SPTBN1 -6572 -6164
SPTBN2 -5447 -3871
SPTBN5 -7557 -461
STX17 -4480 -10772
STX5 3566 8258
TBC1D20 -6556 3818
TFG 8930 6725
TGFA 7935 9686
TMED10 35 2168
TMED2 6426 6360
TMED3 -2098 4751
TMED7 9038 7918
TMED9 917 9007
TMEM115 31 6881
TRAPPC1 5277 9110
TRAPPC10 -10478 -2812
TRAPPC2 -8890 -5344
TRAPPC2L -350 -932
TRAPPC3 6827 7922
TRAPPC4 -7161 -2663
TRAPPC5 4081 6280
TRAPPC6A -7665 -10218
TRAPPC6B 6230 4019
TRAPPC9 921 7473
USO1 6916 3905
YKT6 -3724 6818



Signaling by NOTCH

Signaling by NOTCH
metric value
setSize 182
pMANOVA 4.6e-15
p.adjustMANOVA 2.51e-13
s.dist 0.405
s.low.CRP 0.206
s.high.CRP 0.349
p.low.CRP 1.67e-06
p.high.CRP 4.6e-16




Top 20 genes
Gene low CRP high CRP
NUMB 10040 10006
TACC3 10034 9583
H2BC21 9852 9656
NCSTN 9503 9869
AGO4 9771 9580
H2AJ 8999 10117
MAML3 9463 9534
HDAC4 9329 9546
H2BC12 9066 9812
ADAM10 9314 9481
RBPJ 9652 9125
JAG1 9550 8956
H3-3A 9297 9034
FURIN 8111 10053
TFDP1 9824 8225
ADAM17 8058 9718
EGF 9244 8355
PSME3 9120 8239
PSMD6 8841 8304
RAB6A 8487 8616

Click HERE to show all gene set members

All member genes
low CRP high CRP
ACTA2 -1750.0 1138.0
ADAM10 9314.0 9481.0
ADAM17 8058.0 9718.0
AGO1 2933.0 7911.0
AGO2 2783.0 4361.0
AGO3 5298.0 -2808.0
AGO4 9771.0 9580.0
AKT1 -4794.0 6231.0
APH1A -3379.0 6321.0
APH1B 6306.0 6678.0
ARRB1 -4581.0 4541.0
ARRB2 7827.0 9274.0
ATP2A1 -4808.0 -3244.0
ATP2A2 8393.0 8341.0
ATP2A3 -9252.0 3112.0
B4GALT1 -4177.0 7099.0
CCNC 7860.0 -2135.0
CCND1 -4303.0 -5618.0
CDK8 -3688.0 1375.0
CREB1 4878.0 -3476.0
CREBBP -4951.0 6023.0
CUL1 -2085.0 -10951.0
DLGAP5 1242.0 3313.0
DLL1 -10099.0 -11006.0
DTX1 3485.0 -5093.0
DTX2 4632.0 8118.0
DTX4 1850.0 7305.0
E2F1 6782.0 6864.0
E2F3 4978.0 7309.0
EGF 9244.0 8355.0
ELF3 1642.0 558.0
EP300 4311.0 7552.0
FBXW7 -5277.0 -3657.0
FCER2 -951.0 -3382.0
FLT4 -5969.0 -7884.0
FURIN 8111.0 10053.0
GZMB -11253.0 -9712.0
H2AC20 -790.0 6112.0
H2AC6 8700.0 8169.0
H2AJ 8999.0 10117.0
H2AZ1 1779.0 7321.0
H2AZ2 -4042.0 2210.0
H2BC11 8424.0 8288.0
H2BC12 9066.0 9812.0
H2BC15 3036.0 6455.0
H2BC17 7882.0 7312.0
H2BC21 9852.0 9656.0
H2BC4 7156.0 7805.0
H2BC5 7596.0 8773.0
H2BC9 7965.0 4715.0
H2BU1 -6349.0 -3895.0
H3-3A 9297.0 9034.0
H3C15 5262.5 7402.5
HDAC1 -3835.0 3708.0
HDAC10 -489.0 4165.0
HDAC11 804.0 5759.0
HDAC2 8973.0 3999.0
HDAC3 1719.0 6319.0
HDAC4 9329.0 9546.0
HDAC5 3359.0 5480.0
HDAC6 -7766.0 -5123.0
HDAC7 4750.0 7247.0
HDAC8 3980.0 4023.0
HDAC9 6738.0 -815.0
HES1 -10141.0 -3420.0
HIF1A 7330.0 7808.0
IKZF1 -9076.0 -2554.0
ITCH -2889.0 3792.0
JAG1 9550.0 8956.0
JAG2 -10015.0 -8085.0
JUN 2838.0 4810.0
KAT2A -6742.0 -10405.0
KAT2B 116.0 -1532.0
LFNG -9497.0 -3283.0
MAML1 -81.0 7084.0
MAML2 3788.0 -1483.0
MAML3 9463.0 9534.0
MAMLD1 -532.0 -6686.0
MDK -1527.0 -3362.0
MFNG -7860.0 -990.0
MIB1 3219.0 -3926.0
MIB2 -10461.0 -7734.0
MOV10 -10256.0 -10510.0
MYC 8429.0 -2186.0
NBEA 3872.0 -2283.0
NCOR1 3309.0 7790.0
NCOR2 4843.0 9646.0
NCSTN 9503.0 9869.0
NEURL1 -11174.0 -6488.0
NEURL1B -9540.0 2352.0
NOTCH1 -6446.0 6708.0
NOTCH2 4412.0 6414.0
NOTCH3 -744.0 9587.0
NOTCH4 -10586.0 1602.0
NUMB 10040.0 10006.0
PBX1 1959.0 6243.0
PLXND1 6191.0 8701.0
POFUT1 -435.0 3675.0
POGLUT1 -5394.0 -7044.0
PRKCI 6134.0 -2289.0
PSEN1 7889.0 8878.0
PSEN2 -5169.0 -5867.0
PSENEN 2692.0 7551.0
PSMA1 8278.0 7406.0
PSMA2 5830.0 5666.0
PSMA3 4646.0 -7621.0
PSMA4 3950.0 -1036.0
PSMA5 -2119.0 -3983.0
PSMA6 6893.0 5865.0
PSMA7 3550.0 8554.0
PSMB1 3915.0 4224.0
PSMB10 -7878.0 -1272.0
PSMB2 2664.0 4928.0
PSMB3 4971.0 8382.0
PSMB4 -3175.0 4911.0
PSMB5 6561.0 9138.0
PSMB6 1312.0 8784.0
PSMB7 8034.0 9051.0
PSMB8 -4481.0 75.0
PSMB9 -9105.0 -10433.0
PSMC1 6759.0 7782.0
PSMC2 -2524.0 4517.0
PSMC3 -4971.0 4984.0
PSMC4 -10757.0 -336.0
PSMC5 -3424.0 2764.0
PSMC6 8812.0 6000.0
PSMD1 7679.0 7587.0
PSMD10 2067.0 2450.0
PSMD11 6914.0 6824.0
PSMD12 9011.0 5710.0
PSMD13 3157.0 7205.0
PSMD14 2891.0 3041.0
PSMD2 4352.0 8396.0
PSMD3 -2243.0 6367.0
PSMD4 6858.0 9449.0
PSMD5 2770.0 4781.0
PSMD6 8841.0 8304.0
PSMD7 6534.0 6147.0
PSMD8 739.0 7117.0
PSMD9 3580.0 9001.0
PSME1 -7256.0 -7913.0
PSME2 -5548.0 -10355.0
PSME3 9120.0 8239.0
PSMF1 6709.0 6770.0
PTCRA 8101.0 8187.0
RAB6A 8487.0 8616.0
RBPJ 9652.0 9125.0
RBX1 1418.0 4877.0
RFNG 7041.0 8287.0
RPS27A -3555.0 -7070.0
RUNX1 7796.0 7867.0
SEL1L 7157.0 7252.0
SEM1 993.0 5942.0
SIRT6 2567.0 8277.0
SKP1 8120.0 2700.0
SMAD3 -10084.0 -10081.0
SNW1 6824.0 5161.0
ST3GAL3 2775.0 828.0
ST3GAL4 -9921.0 7993.0
ST3GAL6 9317.0 5155.0
STAT1 -7385.0 -11118.0
TACC3 10034.0 9583.0
TBL1X 8359.0 8499.0
TBL1XR1 4714.0 4779.0
TFDP1 9824.0 8225.0
TFDP2 -11249.0 -10144.0
TLE1 -10867.0 400.0
TLE2 3990.0 -9885.0
TLE3 6965.0 9696.0
TLE4 2341.0 8265.0
TMED2 6426.0 6360.0
TNRC6A -831.0 -4972.0
TNRC6B -4840.0 -2293.0
TNRC6C -10738.0 -9183.0
TP53 -7284.0 -8934.0
UBA52 -1875.0 3023.0
UBB 8251.0 6157.0
UBC -1915.0 5825.0
WWC1 2740.0 953.0
WWP2 6396.0 8805.0
YBX1 -3216.0 5187.0
YWHAZ 5165.0 5861.0



Toll Like Receptor 4 (TLR4) Cascade

Toll Like Receptor 4 (TLR4) Cascade
metric value
setSize 121
pMANOVA 5.54e-15
p.adjustMANOVA 2.9e-13
s.dist 0.511
s.low.CRP 0.283
s.high.CRP 0.425
p.low.CRP 7.62e-08
p.high.CRP 6.13e-16




Top 20 genes
Gene low CRP high CRP
S100A12 10088 10121
ITGAM 9846 10065
CD36 10064 9814
DUSP3 9937 9647
NKIRAS2 9581 9936
MAPK14 9907 9606
APP 9951 9504
UBE2D1 9825 9491
IRAK3 9660 9553
CD14 9551 9658
TLR4 9494 9617
TLR2 9930 9118
MAP2K1 9163 9879
MAP2K6 9435 9577
TLR6 9634 9209
TLR1 9828 8868
MAPK3 8931 9626
LY96 9529 8995
PELI2 9242 9060
MAP2K3 8978 9308

Click HERE to show all gene set members

All member genes
low CRP high CRP
AGER -1839 3181
APP 9951 9504
ATF1 7833 5463
ATF2 7002 164
BIRC2 8079 3449
BIRC3 -2270 -11079
BPI 9613 4607
BTK 7623 7870
BTRC -6845 -441
CASP8 -10359 -8523
CD14 9551 9658
CD180 -749 281
CD36 10064 9814
CHUK 9198 7663
CREB1 4878 -3476
CUL1 -2085 -10951
DNM1 6883 3239
DNM2 -6816 8202
DNM3 7927 7198
DUSP3 9937 9647
DUSP4 -6630 -4192
DUSP6 7994 2589
DUSP7 -4748 387
ECSIT 4110 5590
ELK1 -355 3195
FADD -3611 7477
FBXW11 4585 7364
FOS 6663 6569
HMGB1 3876 -968
IKBKB -5276 -2118
IKBKE 387 6793
IKBKG -3058 7903
IRAK1 2444 7601
IRAK2 -11058 -2404
IRAK3 9660 9553
IRF3 -6904 -7151
IRF7 -8896 -5369
ITGAM 9846 10065
ITGB2 8042 10007
JUN 2838 4810
LY86 9457 6684
LY96 9529 8995
MAP2K1 9163 9879
MAP2K3 8978 9308
MAP2K4 6895 7431
MAP2K6 9435 9577
MAP2K7 -2754 4813
MAP3K1 5466 5938
MAP3K7 1546 4274
MAP3K8 -7139 8928
MAPK1 1052 9260
MAPK10 6734 3872
MAPK11 7257 1843
MAPK14 9907 9606
MAPK3 8931 9626
MAPK7 -10125 5069
MAPK8 -1061 -9914
MAPK9 -6530 -1870
MAPKAPK2 -10572 6892
MAPKAPK3 7493 9250
MEF2A 9000 8162
MEF2C 6943 -2868
MYD88 8651 8344
NFKB1 7857 6377
NFKB2 3069 -1167
NFKBIA 6855 7374
NFKBIB -9679 5479
NKIRAS1 2619 689
NKIRAS2 9581 9936
NOD1 -10930 -10348
NOD2 9408 8613
PELI1 9064 5690
PELI2 9242 9060
PELI3 5708 8764
PLCG2 -4618 6826
PPP2CA 8810 8328
PPP2CB 8482 7631
PPP2R1A -3087 6994
PPP2R1B 2503 437
PPP2R5D -6508 4985
PTPN11 4691 6614
PTPN4 -10946 -10632
RELA -7305 2739
RIPK1 -10879 -4699
RIPK2 1665 2297
RIPK3 -5133 7348
RPS27A -3555 -7070
RPS6KA1 -105 9153
RPS6KA2 -5428 3882
RPS6KA3 2859 3437
RPS6KA5 -3980 -11177
S100A12 10088 10121
S100B -8212 -1271
SARM1 -10456 -10950
SIGIRR -9900 -8613
SKP1 8120 2700
SOCS1 -219 6051
TAB1 6623 5746
TAB2 9197 5726
TAB3 3912 3647
TANK 8959 7267
TBK1 5846 2973
TICAM1 6742 6552
TICAM2 9182 4768
TIRAP 262 7730
TLR1 9828 8868
TLR2 9930 9118
TLR4 9494 9617
TLR6 9634 9209
TNIP2 -1490 7359
TRAF3 2694 -5265
TRAF6 -1767 2089
UBA52 -1875 3023
UBB 8251 6157
UBC -1915 5825
UBE2D1 9825 9491
UBE2D2 2673 5593
UBE2D3 9443 8783
UBE2N 4087 2050
UBE2V1 6665 5995
VRK3 -7245 5798



Transport of small molecules

Transport of small molecules
metric value
setSize 554
pMANOVA 6e-15
p.adjustMANOVA 3.03e-13
s.dist 0.25
s.low.CRP 0.154
s.high.CRP 0.196
p.low.CRP 5.35e-10
p.high.CRP 2.54e-15




Top 20 genes
Gene low CRP high CRP
MICU1 10005 10032
ASPH 10044 9989
CYB5R1 9974 10035
ATP6V0A1 9995 10010
PRKACA 9885 10068
FBXL5 10052 9713
ATP6V1A 9857 9880
GNG10 9939 9753
ANO10 9759 9887
SLC36A1 9603 10029
SLC1A3 9671 9889
CA1 10107 9363
TRPV4 9655 9798
MCU 10020 9438
ATP6V0D1 9444 9942
TRPM2 9480 9785
SLC2A3 9614 9612
BSG 9373 9841
SLC22A4 9718 9483
AQP9 9134 10041

Click HERE to show all gene set members

All member genes
low CRP high CRP
A2M -7113 -9795
ABCA1 5566 7323
ABCA10 -7352 -8191
ABCA2 -10984 -4176
ABCA3 -10824 -8696
ABCA5 -2102 -9305
ABCA6 -2645 -2268
ABCA7 947 3947
ABCA9 1122 -1518
ABCB1 -11223 -9699
ABCB10 5595 6961
ABCB4 -1968 -4715
ABCB6 8402 6175
ABCB7 6690 -2967
ABCB8 -861 846
ABCB9 4732 -5876
ABCC1 686 2817
ABCC10 -8751 1068
ABCC2 -1995 -911
ABCC3 5573 6872
ABCC4 8425 7787
ABCC5 1929 3348
ABCC6 8075 4650
ABCC9 -7760 -1242
ABCD1 6353 8582
ABCD2 -3715 -11096
ABCD3 6391 5067
ABCF1 -8740 -5720
ABCG1 -7719 -6299
ABCG2 -3030 1489
ABCG8 4588 3009
ACO1 503 -8616
ADCY2 -4785 -910
ADCY3 8645 9780
ADCY4 4042 6126
ADCY5 -8988 -4426
ADCY6 -4846 651
ADCY7 -8603 2306
ADCY9 -3025 2535
ADD1 -5862 7957
ADD2 -1794 -5132
ADD3 3544 3968
AFG3L2 -6199 -9227
AHCYL2 4690 368
AKAP1 -6703 -10750
ALAD 8384 9011
ALB 1254 3551
AMN 2539 -5736
ANGPTL4 -7923 824
ANKH -9468 -10925
ANO10 9759 9887
ANO5 7903 2752
ANO6 9199 8127
ANO7 7565 -7642
ANO8 6301 6525
ANO9 -2087 -10728
AP2A1 -3194 9104
AP2A2 3196 9217
AP2B1 -9145 2444
AP2M1 7742 9334
AP2S1 7422 8877
APOA2 2715 7325
APOBR 2559 8870
APOE -5022 1771
AQP1 8407 7513
AQP10 7215 8700
AQP11 5506 -6191
AQP3 -3533 -11123
AQP7 -7159 -4368
AQP9 9134 10041
ARL2 -5078 2617
ARL2BP -632 -4418
ASIC1 -897 -3801
ASIC3 835 -9272
ASPH 10044 9989
ATP10A -11002 -10737
ATP10B 7756 -438
ATP10D 4920 2259
ATP11A 8506 9066
ATP11B 1885 6335
ATP11C 4979 3355
ATP13A1 -4351 -3131
ATP13A2 -8295 6577
ATP13A4 -5313 -7790
ATP1A1 -1628 4842
ATP1A3 -10997 -7709
ATP1A4 -752 1945
ATP1B1 -8715 -6224
ATP1B2 7770 5919
ATP1B3 -6365 2479
ATP2A1 -4808 -3244
ATP2A2 8393 8341
ATP2A3 -9252 3112
ATP2B1 -1673 -8000
ATP2B4 -10512 2227
ATP2C1 2958 6179
ATP2C2 6778 7461
ATP6AP1 2039 9790
ATP6V0A1 9995 10010
ATP6V0A2 -10623 -10379
ATP6V0B 8163 9396
ATP6V0C 9348 9734
ATP6V0D1 9444 9942
ATP6V0E1 8171 9289
ATP6V0E2 -8802 -11036
ATP6V1A 9857 9880
ATP6V1B2 9738 9281
ATP6V1C1 9888 8528
ATP6V1C2 2655 -3376
ATP6V1D 9600 9482
ATP6V1E1 8095 8397
ATP6V1E2 8322 4968
ATP6V1F 3461 6917
ATP6V1G1 5204 4277
ATP6V1G2 -4714 -10140
ATP6V1H 7942 8571
ATP7A -5957 3433
ATP7B 6812 7681
ATP8A1 -9269 -10981
ATP8A2 1403 -6704
ATP8B1 -1091 -5907
ATP8B2 -4710 -11034
ATP8B3 227 6637
ATP8B4 7888 7537
ATP9A -10751 7197
ATP9B -158 7725
AVPR2 1919 -154
BEST1 7982 8056
BEST2 7074 1086
BEST3 7447 7131
BEST4 -3229 -9156
BMP1 -7547 3598
BSG 9373 9841
BSND 4290 5437
CA1 10107 9363
CA2 3967 3723
CA4 6753 9451
CALM1 -6645 1321
CAMK2D -9328 -10857
CAMK2G -646 3153
CAND1 3497 -7234
CES3 -9501 -5359
CETP 7648 906
CLCN1 971 5688
CLCN2 -3747 1774
CLCN3 7695 7837
CLCN4 6355 5007
CLCN5 9018 5830
CLCN6 4520 2014
CLCN7 1865 2568
CLIC2 -8491 -3257
CLTA 8416 8998
CLTC 9376 9720
CP -4947 388
CTNS 2545 8440
CUBN -446 -9567
CUL1 -2085 -10951
CUTC -3554 5647
CYB5R1 9974 10035
CYB5R2 9250 8814
CYB5R4 9323 8621
CYB5RL -7036 -10449
CYBRD1 7494 5244
DERL1 -8912 -3885
DERL2 4947 3337
DERL3 -8166 -4909
DMTN 9922 8657
EIF2S1 7895 2992
EIF2S2 8600 5536
EIF2S3 8904 6013
EMB 8216 7393
ERLEC1 157 2344
ERLIN1 9781 9270
ERLIN2 8632 9807
FBXL5 10052 9713
FKBP1B 5975 8039
FLVCR1 -5808 -6526
FTH1 3543 5337
FTL 8704 9324
FURIN 8111 10053
FXYD1 -6959 -3100
FXYD2 -384 -5695
FXYD3 -9980 -4578
FXYD6 8916 6736
FXYD7 -1051 -9615
GLRX3 6063 -2744
GNAS 8297 8173
GNB1 6908 9175
GNB2 6587 9064
GNB3 7806 -8406
GNB4 9340 6537
GNB5 6182 -475
GNG10 9939 9753
GNG11 8239 6403
GNG2 -10761 192
GNG3 4993 -794
GNG4 414 -2445
GNG5 8894 9403
GNG7 -2881 -4054
GNG8 4092 4604
GNGT2 -11227 -6988
HBA1 10009 8734
HBB 10013 8750
HDLBP 6586 9343
HFE 10047 7215
HMOX1 6942 9285
HMOX2 -10770 -8356
IREB2 6581 5640
KCNJ11 -2546 -3545
LCAT -1035 112
LCN12 -10547 -6968
LCN15 6603 -4207
LCN2 9447 6200
LDLR 2463 6531
LDLRAP1 -668 -10304
LETM1 -7946 1396
LIPA 8548 5901
LIPC -1245 2212
LIPG 2603 -2762
LMF1 -5477 -8928
LMF2 -7328 -4959
LPL -2018 4002
LRRC8A -10336 -760
LRRC8B 7153 1702
LRRC8C 7148 -2443
LRRC8D 8333 3881
LSR 2813 -8994
MAGT1 574 3711
MBTPS1 1704 4208
MBTPS2 2221 584
MCOLN1 6111 8804
MCOLN2 -9600 -10429
MCOLN3 5352 -9129
MCU 10020 9438
MCUB 6013 -4771
MFSD4B 784 -4179
MICU1 10005 10032
MICU2 -994 990
MICU3 -509 -8211
MMGT1 8569 6908
MRS2 2918 -6149
MYLIP -4440 -1671
MYO5B -6423 -8111
NCEH1 9765 8961
NEDD4L 8246 8260
NEDD8 -156 8587
NIPA1 -9840 -8930
NIPA2 315 5867
NIPAL1 3101 3779
NIPAL2 3117 1538
NIPAL3 -5419 -10130
NIPAL4 -2736 1066
NPC1 -11209 -7468
NPC2 6632 5511
NR1H2 4003 8448
NR1H3 -8939 2196
OS9 8889 9708
OSTM1 7343 7263
P4HB 6474 9641
PARL 8755 9806
PCSK5 6394 4664
PCSK6 9717 9061
PDZD11 -9036 -585
PEX19 337 7251
PEX3 -8841 -11221
PHB -4398 564
PHB2 -3335 2761
PLTP 1710 9224
PMPCA -968 -5040
PMPCB 4611 -1325
PRKACA 9885 10068
PRKACB -9852 -10936
PRKAR1A 8455 9570
PRKAR1B 8879 7874
PRKAR2A 3755 7093
PRKAR2B 7943 7189
PSMA1 8278 7406
PSMA2 5830 5666
PSMA3 4646 -7621
PSMA4 3950 -1036
PSMA5 -2119 -3983
PSMA6 6893 5865
PSMA7 3550 8554
PSMB1 3915 4224
PSMB10 -7878 -1272
PSMB2 2664 4928
PSMB3 4971 8382
PSMB4 -3175 4911
PSMB5 6561 9138
PSMB6 1312 8784
PSMB7 8034 9051
PSMB8 -4481 75
PSMB9 -9105 -10433
PSMC1 6759 7782
PSMC2 -2524 4517
PSMC3 -4971 4984
PSMC4 -10757 -336
PSMC5 -3424 2764
PSMC6 8812 6000
PSMD1 7679 7587
PSMD10 2067 2450
PSMD11 6914 6824
PSMD12 9011 5710
PSMD13 3157 7205
PSMD14 2891 3041
PSMD2 4352 8396
PSMD3 -2243 6367
PSMD4 6858 9449
PSMD5 2770 4781
PSMD6 8841 8304
PSMD7 6534 6147
PSMD8 739 7117
PSMD9 3580 9001
PSME1 -7256 -7913
PSME2 -5548 -10355
PSME3 9120 8239
PSME4 -5205 -3127
PSMF1 6709 6770
RAB11A 9786 8252
RAB11FIP2 8534 3310
RAF1 8477 8327
RNF185 3476 7488
RNF5 -8439 -1294
RPS27A -3555 -7070
RSC1A1 3785 390
RUNX1 7796 7867
RYR1 -7935 -1799
RYR2 4903 7593
RYR3 -6590 -9544
SAR1B 8795 5984
SCARB1 7210 6035
SCNN1A -7948 3665
SCNN1D -775 -6625
SEL1L 7157 7252
SEM1 993 5942
SGK1 8717 2303
SGK2 -5387 -5325
SGK3 9971 5723
SKP1 8120 2700
SLC11A1 9129 9947
SLC11A2 3408 211
SLC12A1 5311 1287
SLC12A2 -7210 -10523
SLC12A3 -11066 -7173
SLC12A4 -205 4089
SLC12A6 8049 8895
SLC12A7 -3382 -817
SLC13A3 -10762 -7483
SLC13A4 1661 -3627
SLC13A5 2839 -2730
SLC14A1 -6548 -5268
SLC14A2 -3727 -2374
SLC15A2 4216 3940
SLC15A3 8196 9400
SLC15A4 -8597 6968
SLC16A1 7992 3127
SLC16A10 4849 -9439
SLC16A3 7685 9834
SLC16A7 6212 5286
SLC16A8 -6480 3682
SLC17A5 3558 5793
SLC17A7 415 1260
SLC18A1 -10097 -10310
SLC18A2 4005 -935
SLC1A2 -2025 528
SLC1A3 9671 9889
SLC1A4 -9395 -9098
SLC1A5 7029 6558
SLC1A6 5588 -3984
SLC1A7 -10898 -4673
SLC20A1 -8929 -9775
SLC20A2 -10973 -5662
SLC22A1 -2572 6250
SLC22A15 9487 9659
SLC22A16 7319 4886
SLC22A17 4778 -6347
SLC22A18 3118 4851
SLC22A4 9718 9483
SLC22A5 8129 6640
SLC24A1 -9823 -8533
SLC24A2 7606 4390
SLC24A3 7346 5290
SLC24A4 8871 7763
SLC25A10 -9533 -7148
SLC25A18 106 3849
SLC25A22 -2556 -5545
SLC25A26 -10145 -11197
SLC25A29 1266 3359
SLC25A4 -9712 -10587
SLC25A5 -2120 2904
SLC25A6 1188 8323
SLC26A1 -4438 -7156
SLC26A11 -4333 -6304
SLC26A2 -2767 -643
SLC26A6 7512 9359
SLC27A1 9371 8373
SLC27A4 -5321 5621
SLC28A2 5453 -4178
SLC28A3 3399 6847
SLC29A1 -6224 4388
SLC29A2 -3858 -10264
SLC29A3 1184 6100
SLC29A4 -5956 583
SLC2A1 -11011 -6196
SLC2A10 -4010 -4079
SLC2A11 -2101 -6357
SLC2A12 -3084 -5337
SLC2A13 3423 3470
SLC2A14 590 7158
SLC2A3 9614 9612
SLC2A6 -5791 45
SLC2A8 -10538 -9148
SLC2A9 9391 5291
SLC30A1 8984 8371
SLC30A2 -2211 897
SLC30A5 4019 -2234
SLC30A6 3288 356
SLC30A7 2244 -5266
SLC31A1 9575 9377
SLC33A1 1768 -1430
SLC34A1 -6058 865
SLC34A2 6195 -1412
SLC34A3 -7246 -5460
SLC35A1 9102 6415
SLC35A2 -8815 6460
SLC35A3 -474 -9691
SLC35B2 -9784 -6175
SLC35B3 7339 5568
SLC35B4 -1247 5097
SLC35C1 1561 3694
SLC35D1 -5746 -4085
SLC35D2 8843 7622
SLC36A1 9603 10029
SLC36A2 -6167 1367
SLC36A4 8563 7899
SLC38A1 -9343 -10151
SLC38A2 8443 5615
SLC38A5 -3625 -4088
SLC39A1 7841 9638
SLC39A10 -6232 -9463
SLC39A14 -1615 -5823
SLC39A3 -2007 6305
SLC39A4 3879 5035
SLC39A5 -2687 -6244
SLC39A6 -2294 -6278
SLC39A7 -6602 7846
SLC39A8 6310 9040
SLC3A1 -8293 -6078
SLC3A2 200 6877
SLC40A1 9430 7018
SLC41A1 -9944 -9767
SLC41A2 -11229 -11224
SLC43A1 -5734 -1137
SLC43A2 8127 8975
SLC44A1 9313 9124
SLC44A2 -8609 5338
SLC44A5 -358 -4399
SLC45A3 1265 -9112
SLC46A1 589 2726
SLC47A1 -7291 999
SLC47A2 -4175 -5958
SLC4A1 10074 8897
SLC4A10 -6861 -8208
SLC4A2 6807 8584
SLC4A3 -11221 -10667
SLC4A4 -11006 -8671
SLC4A5 5877 -8685
SLC4A7 -9115 -11094
SLC4A8 -10063 -7433
SLC50A1 6405 3626
SLC5A10 -1989 -10501
SLC5A11 -628 -1330
SLC5A12 4480 -955
SLC5A2 666 -5529
SLC5A3 -8472 -9832
SLC5A5 4358 -8309
SLC5A6 -1016 -4649
SLC5A9 -6157 7420
SLC66A1 -780 6697
SLC6A1 -1952 -324
SLC6A12 5563 3015
SLC6A20 -5383 -3251
SLC6A6 9214 9582
SLC6A9 9676 5765
SLC7A1 -2351 -5269
SLC7A11 -6301 -3656
SLC7A5 -2245 4782
SLC7A6 2433 -8284
SLC7A7 7699 7341
SLC7A8 5188 -110
SLC8A1 9278 8733
SLC8A3 4564 690
SLC8B1 6747 8813
SLC9A1 3224 9393
SLC9A3 -986 -9168
SLC9A5 -6333 -6395
SLC9A6 2707 5538
SLC9A7 -7071 -4854
SLC9A8 -7606 6915
SLC9A9 7672 7876
SLC9B1 -1636 -6010
SLC9B2 -9079 -10099
SLCO2B1 8444 8881
SLCO3A1 8468 9073
SLCO4A1 4460 4319
SLCO4C1 -10306 5158
SMDT1 -174 1484
SOAT1 8985 8730
SOAT2 3957 -4998
SPG7 -8333 -10338
SRI 5491 7505
STEAP3 1711 7554
STOM 1151 7088
STOML2 -4910 237
TCIRG1 1085 9058
TF 1794 1244
TFR2 -8721 -7475
TFRC 2181 1526
TPCN1 9203 3539
TPCN2 5713 7828
TRPC1 -2448 -10832
TRPC3 -9747 -5879
TRPC4AP -6506 5324
TRPC6 -4419 130
TRPM2 9480 9785
TRPM3 1786 659
TRPM4 8778 5730
TRPM6 -2890 4649
TRPM7 183 -7309
TRPV1 -902 -10436
TRPV2 -10779 2209
TRPV3 -10616 -6801
TRPV4 9655 9798
TRPV6 4072 -7490
TSC22D3 -6050 5999
TTYH1 -5959 2122
TTYH2 -5424 -2107
TTYH3 3631 9210
UBA52 -1875 3023
UBB 8251 6157
UBC -1915 5825
UNC79 -696 7436
UNC80 -6025 2485
VCP 3600 7754
VDAC1 6643 4063
VDAC2 8674 7660
VDAC3 463 1981
VLDLR -9564 1877
WNK1 1792 6919
WNK2 1347 1603
WNK3 771 -5698
WWP1 813 -10536
YME1L1 7609 5930
ZDHHC8 -2251 -1730



Classical antibody-mediated complement activation

Classical antibody-mediated complement activation
metric value
setSize 68
pMANOVA 7.31e-15
p.adjustMANOVA 3.56e-13
s.dist 0.366
s.low.CRP 0.161
s.high.CRP -0.328
p.low.CRP 0.0216
p.high.CRP 2.87e-06




Top 20 genes
Gene low CRP high CRP
IGKV3-11 5548 -7167
IGKV1-33 5955 -6384
IGKV1-16 6217 -5451
IGKV1-5 6127 -5162
IGLV5-45 4194 -7364
IGHV3-23 6032 -5092
IGKV2-30 5205 -5349
IGLV1-44 4742 -5791
IGHV4-59 4532 -5870
IGLV2-8 4818 -5256
IGHV4-39 3786 -6542
IGLV3-19 4006 -5611
IGHV1-2 5956 -3146
IGKV3-20 3704 -5021
IGKC 2773 -6437
IGLV1-36 3522 -5030
IGHV3-11 3518 -4591
IGHV3-7 4185 -3630
IGKV3-15 3174 -4687
IGKV4-1 2812 -4988

Click HERE to show all gene set members

All member genes
low CRP high CRP
C1QA -49 7890
C1QB 6746 8930
C1QC 7805 9340
C1R -10393 -4020
C1S -6159 552
IGHG1 -1124 -7111
IGHG2 -5587 -6004
IGHG3 -507 -4089
IGHG4 -4038 -5940
IGHV1-2 5956 -3146
IGHV1-46 3766 -2976
IGHV1-69 2354 -2328
IGHV2-5 4451 -1972
IGHV2-70 -3315 -2159
IGHV3-11 3518 -4591
IGHV3-13 799 -2451
IGHV3-23 6032 -5092
IGHV3-30 2500 -5193
IGHV3-33 98 -4138
IGHV3-48 3183 -4340
IGHV3-53 3131 -1786
IGHV3-7 4185 -3630
IGHV4-34 1144 -4007
IGHV4-39 3786 -6542
IGHV4-59 4532 -5870
IGKC 2773 -6437
IGKV1-12 725 -6674
IGKV1-16 6217 -5451
IGKV1-17 -241 -2794
IGKV1-33 5955 -6384
IGKV1-5 6127 -5162
IGKV1D-39 5018 -2677
IGKV2-28 1440 -6662
IGKV2-30 5205 -5349
IGKV2D-28 -7224 -2947
IGKV3-11 5548 -7167
IGKV3-15 3174 -4687
IGKV3-20 3704 -5021
IGKV3D-20 -1830 -4618
IGKV4-1 2812 -4988
IGKV5-2 5226 -2682
IGLC1 -2813 -6176
IGLC2 -258 -6539
IGLC3 -2958 -4378
IGLC7 -3403 -4490
IGLV1-36 3522 -5030
IGLV1-40 163 -5497
IGLV1-44 4742 -5791
IGLV1-47 231 -6633
IGLV1-51 1708 -6601
IGLV10-54 -5422 316
IGLV2-11 870 -3205
IGLV2-14 -5127 -8197
IGLV2-18 2015 -2963
IGLV2-23 2029 -4201
IGLV2-8 4818 -5256
IGLV3-1 -96 -5140
IGLV3-12 -7299 -6816
IGLV3-19 4006 -5611
IGLV3-21 -975 -6062
IGLV3-25 -942 -5485
IGLV3-27 -5365 -4834
IGLV4-69 1344 -2261
IGLV5-45 4194 -7364
IGLV6-57 1834 -5837
IGLV7-43 4854 -2823
IGLV7-46 2445 -3619
IGLV8-61 -3989 -5208



Binding and Uptake of Ligands by Scavenger Receptors

Binding and Uptake of Ligands by Scavenger Receptors
metric value
setSize 91
pMANOVA 9.23e-15
p.adjustMANOVA 4.34e-13
s.dist 0.314
s.low.CRP 0.28
s.high.CRP -0.142
p.low.CRP 3.95e-06
p.high.CRP 0.019




Top 20 genes
Gene low CRP high CRP
JCHAIN 4874 -8700
IGKV3-11 5548 -7167
IGKV1-33 5955 -6384
IGKV1-16 6217 -5451
IGKV1-5 6127 -5162
IGLV5-45 4194 -7364
IGHV3-23 6032 -5092
IGHA1 4926 -5918
IGKV2-30 5205 -5349
IGLV1-44 4742 -5791
IGHV4-59 4532 -5870
IGLV2-8 4818 -5256
IGHV4-39 3786 -6542
IGLV3-19 4006 -5611
IGHV1-2 5956 -3146
IGKV3-20 3704 -5021
IGKC 2773 -6437
IGLV1-36 3522 -5030
IGHV3-11 3518 -4591
IGHV3-7 4185 -3630

Click HERE to show all gene set members

All member genes
low CRP high CRP
ALB 1254 3551
APOE -5022 1771
APOL1 -7427 -4732
CALR 6685 6374
CD163 10038 10038
CD36 10064 9814
COL1A2 5690 684
COL4A2 1717 838
COLEC12 -5943 -2495
FTH1 3543 5337
FTL 8704 9324
HBA1 10009 8734
HBB 10013 8750
HP 9925 10000
HPX 477 -1968
HSP90AA1 5309 410
HSP90B1 7042 372
HSPH1 -1504 -8662
HYOU1 -6582 2512
IGHA1 4926 -5918
IGHA2 2335 -2345
IGHV1-2 5956 -3146
IGHV1-46 3766 -2976
IGHV1-69 2354 -2328
IGHV2-5 4451 -1972
IGHV2-70 -3315 -2159
IGHV3-11 3518 -4591
IGHV3-13 799 -2451
IGHV3-23 6032 -5092
IGHV3-30 2500 -5193
IGHV3-33 98 -4138
IGHV3-48 3183 -4340
IGHV3-53 3131 -1786
IGHV3-7 4185 -3630
IGHV4-34 1144 -4007
IGHV4-39 3786 -6542
IGHV4-59 4532 -5870
IGKC 2773 -6437
IGKV1-12 725 -6674
IGKV1-16 6217 -5451
IGKV1-17 -241 -2794
IGKV1-33 5955 -6384
IGKV1-5 6127 -5162
IGKV1D-39 5018 -2677
IGKV2-28 1440 -6662
IGKV2-30 5205 -5349
IGKV2D-28 -7224 -2947
IGKV3-11 5548 -7167
IGKV3-15 3174 -4687
IGKV3-20 3704 -5021
IGKV3D-20 -1830 -4618
IGKV4-1 2812 -4988
IGKV5-2 5226 -2682
IGLC1 -2813 -6176
IGLC2 -258 -6539
IGLC3 -2958 -4378
IGLC7 -3403 -4490
IGLV1-36 3522 -5030
IGLV1-40 163 -5497
IGLV1-44 4742 -5791
IGLV1-47 231 -6633
IGLV1-51 1708 -6601
IGLV10-54 -5422 316
IGLV2-11 870 -3205
IGLV2-14 -5127 -8197
IGLV2-18 2015 -2963
IGLV2-23 2029 -4201
IGLV2-8 4818 -5256
IGLV3-1 -96 -5140
IGLV3-12 -7299 -6816
IGLV3-19 4006 -5611
IGLV3-21 -975 -6062
IGLV3-25 -942 -5485
IGLV3-27 -5365 -4834
IGLV4-69 1344 -2261
IGLV5-45 4194 -7364
IGLV6-57 1834 -5837
IGLV7-43 4854 -2823
IGLV7-46 2445 -3619
IGLV8-61 -3989 -5208
JCHAIN 4874 -8700
LRP1 9226 9878
MARCO 6219 9851
MSR1 -528 1494
SCARB1 7210 6035
SCARF1 6500 -1228
SCGB3A2 718 -1063
SPARC 9073 7195
SSC5D -3756 -4645
STAB1 10077 10111
STAB2 7035 5388



Interleukin-1 signaling

Interleukin-1 signaling
metric value
setSize 97
pMANOVA 1.45e-14
p.adjustMANOVA 6.57e-13
s.dist 0.561
s.low.CRP 0.309
s.high.CRP 0.468
p.low.CRP 1.5e-07
p.high.CRP 1.57e-15




Top 20 genes
Gene low CRP high CRP
S100A12 10088 10121
IL1RN 10087 9470
NKIRAS2 9581 9936
APP 9951 9504
IRAK3 9660 9553
MAP2K1 9163 9879
MAP2K6 9435 9577
IL1R1 9455 9194
PELI2 9242 9060
NOD2 9408 8613
TOLLIP 8447 9165
MAP3K3 8280 9287
PSME3 9120 8239
PSMD6 8841 8304
PSMB7 8034 9051
MYD88 8651 8344
CHUK 9198 7663
IL1R2 6574 9865
PSMD4 6858 9449
PSMA1 8278 7406

Click HERE to show all gene set members

All member genes
low CRP high CRP
AGER -1839 3181
APP 9951 9504
BTRC -6845 -441
CHUK 9198 7663
CUL1 -2085 -10951
FBXW11 4585 7364
HMGB1 3876 -968
IKBKB -5276 -2118
IKBKG -3058 7903
IL1B 7489 3385
IL1R1 9455 9194
IL1R2 6574 9865
IL1RAP 3294 7375
IL1RN 10087 9470
IRAK1 2444 7601
IRAK2 -11058 -2404
IRAK3 9660 9553
MAP2K1 9163 9879
MAP2K4 6895 7431
MAP2K6 9435 9577
MAP3K3 8280 9287
MAP3K7 1546 4274
MAP3K8 -7139 8928
MYD88 8651 8344
NFKB1 7857 6377
NFKB2 3069 -1167
NFKBIA 6855 7374
NFKBIB -9679 5479
NKIRAS1 2619 689
NKIRAS2 9581 9936
NOD1 -10930 -10348
NOD2 9408 8613
PELI1 9064 5690
PELI2 9242 9060
PELI3 5708 8764
PSMA1 8278 7406
PSMA2 5830 5666
PSMA3 4646 -7621
PSMA4 3950 -1036
PSMA5 -2119 -3983
PSMA6 6893 5865
PSMA7 3550 8554
PSMB1 3915 4224
PSMB10 -7878 -1272
PSMB2 2664 4928
PSMB3 4971 8382
PSMB4 -3175 4911
PSMB5 6561 9138
PSMB6 1312 8784
PSMB7 8034 9051
PSMB8 -4481 75
PSMB9 -9105 -10433
PSMC1 6759 7782
PSMC2 -2524 4517
PSMC3 -4971 4984
PSMC4 -10757 -336
PSMC5 -3424 2764
PSMC6 8812 6000
PSMD1 7679 7587
PSMD10 2067 2450
PSMD11 6914 6824
PSMD12 9011 5710
PSMD13 3157 7205
PSMD14 2891 3041
PSMD2 4352 8396
PSMD3 -2243 6367
PSMD4 6858 9449
PSMD5 2770 4781
PSMD6 8841 8304
PSMD7 6534 6147
PSMD8 739 7117
PSMD9 3580 9001
PSME1 -7256 -7913
PSME2 -5548 -10355
PSME3 9120 8239
PSME4 -5205 -3127
PSMF1 6709 6770
RBX1 1418 4877
RELA -7305 2739
RIPK2 1665 2297
RPS27A -3555 -7070
S100A12 10088 10121
S100B -8212 -1271
SEM1 993 5942
SKP1 8120 2700
SQSTM1 4693 4549
TAB1 6623 5746
TAB2 9197 5726
TAB3 3912 3647
TNIP2 -1490 7359
TOLLIP 8447 9165
TRAF6 -1767 2089
UBA52 -1875 3023
UBB 8251 6157
UBC -1915 5825
UBE2N 4087 2050
UBE2V1 6665 5995



FCGR activation

FCGR activation
metric value
setSize 75
pMANOVA 3.32e-14
p.adjustMANOVA 1.43e-12
s.dist 0.342
s.low.CRP 0.143
s.high.CRP -0.311
p.low.CRP 0.0322
p.high.CRP 3.24e-06




Top 20 genes
Gene low CRP high CRP
IGKV3-11 5548 -7167
IGKV1-33 5955 -6384
IGKV1-16 6217 -5451
IGKV1-5 6127 -5162
IGLV5-45 4194 -7364
IGHV3-23 6032 -5092
IGKV2-30 5205 -5349
IGLV1-44 4742 -5791
IGHV4-59 4532 -5870
IGLV2-8 4818 -5256
IGHV4-39 3786 -6542
IGLV3-19 4006 -5611
IGHV1-2 5956 -3146
IGKV3-20 3704 -5021
IGKC 2773 -6437
IGLV1-36 3522 -5030
IGHV3-11 3518 -4591
IGHV3-7 4185 -3630
IGKV3-15 3174 -4687
IGKV4-1 2812 -4988

Click HERE to show all gene set members

All member genes
low CRP high CRP
CD247 -11271 -10327
CD3G -9054 -10504
FCGR1A 9965 9575
FCGR2A 9414 9249
FCGR3A -11272 -4672
FGR 6254 9666
FYN -10878 -6729
HCK 9286 9494
IGHG1 -1124 -7111
IGHG2 -5587 -6004
IGHG3 -507 -4089
IGHG4 -4038 -5940
IGHV1-2 5956 -3146
IGHV1-46 3766 -2976
IGHV1-69 2354 -2328
IGHV2-5 4451 -1972
IGHV2-70 -3315 -2159
IGHV3-11 3518 -4591
IGHV3-13 799 -2451
IGHV3-23 6032 -5092
IGHV3-30 2500 -5193
IGHV3-33 98 -4138
IGHV3-48 3183 -4340
IGHV3-53 3131 -1786
IGHV3-7 4185 -3630
IGHV4-34 1144 -4007
IGHV4-39 3786 -6542
IGHV4-59 4532 -5870
IGKC 2773 -6437
IGKV1-12 725 -6674
IGKV1-16 6217 -5451
IGKV1-17 -241 -2794
IGKV1-33 5955 -6384
IGKV1-5 6127 -5162
IGKV1D-39 5018 -2677
IGKV2-28 1440 -6662
IGKV2-30 5205 -5349
IGKV2D-28 -7224 -2947
IGKV3-11 5548 -7167
IGKV3-15 3174 -4687
IGKV3-20 3704 -5021
IGKV3D-20 -1830 -4618
IGKV4-1 2812 -4988
IGKV5-2 5226 -2682
IGLC1 -2813 -6176
IGLC2 -258 -6539
IGLC3 -2958 -4378
IGLC7 -3403 -4490
IGLV1-36 3522 -5030
IGLV1-40 163 -5497
IGLV1-44 4742 -5791
IGLV1-47 231 -6633
IGLV1-51 1708 -6601
IGLV10-54 -5422 316
IGLV2-11 870 -3205
IGLV2-14 -5127 -8197
IGLV2-18 2015 -2963
IGLV2-23 2029 -4201
IGLV2-8 4818 -5256
IGLV3-1 -96 -5140
IGLV3-12 -7299 -6816
IGLV3-19 4006 -5611
IGLV3-21 -975 -6062
IGLV3-25 -942 -5485
IGLV3-27 -5365 -4834
IGLV4-69 1344 -2261
IGLV5-45 4194 -7364
IGLV6-57 1834 -5837
IGLV7-43 4854 -2823
IGLV7-46 2445 -3619
IGLV8-61 -3989 -5208
LYN 7575 8379
SRC -6857 -7229
SYK 9464 9848
YES1 -11138 -8566



Initial triggering of complement

Initial triggering of complement
metric value
setSize 77
pMANOVA 3.37e-14
p.adjustMANOVA 1.43e-12
s.dist 0.332
s.low.CRP 0.158
s.high.CRP -0.292
p.low.CRP 0.0165
p.high.CRP 9.18e-06




Top 20 genes
Gene low CRP high CRP
IGKV3-11 5548 -7167
IGKV1-33 5955 -6384
IGKV1-16 6217 -5451
IGKV1-5 6127 -5162
IGLV5-45 4194 -7364
IGHV3-23 6032 -5092
IGKV2-30 5205 -5349
IGLV1-44 4742 -5791
IGHV4-59 4532 -5870
IGLV2-8 4818 -5256
IGHV4-39 3786 -6542
IGLV3-19 4006 -5611
IGHV1-2 5956 -3146
IGKV3-20 3704 -5021
IGKC 2773 -6437
IGLV1-36 3522 -5030
IGHV3-11 3518 -4591
IGHV3-7 4185 -3630
IGKV3-15 3174 -4687
MASP2 2089 -6883

Click HERE to show all gene set members

All member genes
low CRP high CRP
C1QA -49 7890
C1QB 6746 8930
C1QC 7805 9340
C1R -10393 -4020
C1S -6159 552
C2 6634 2959
C3 -11179 -10489
C4A 5060 4740
C4B 6359 2884
CFB -3014 -2968
CFD 2998 2390
FCN1 9889 9103
GZMM -11118 -8768
IGHG1 -1124 -7111
IGHG2 -5587 -6004
IGHG3 -507 -4089
IGHG4 -4038 -5940
IGHV1-2 5956 -3146
IGHV1-46 3766 -2976
IGHV1-69 2354 -2328
IGHV2-5 4451 -1972
IGHV2-70 -3315 -2159
IGHV3-11 3518 -4591
IGHV3-13 799 -2451
IGHV3-23 6032 -5092
IGHV3-30 2500 -5193
IGHV3-33 98 -4138
IGHV3-48 3183 -4340
IGHV3-53 3131 -1786
IGHV3-7 4185 -3630
IGHV4-34 1144 -4007
IGHV4-39 3786 -6542
IGHV4-59 4532 -5870
IGKC 2773 -6437
IGKV1-12 725 -6674
IGKV1-16 6217 -5451
IGKV1-17 -241 -2794
IGKV1-33 5955 -6384
IGKV1-5 6127 -5162
IGKV1D-39 5018 -2677
IGKV2-28 1440 -6662
IGKV2-30 5205 -5349
IGKV2D-28 -7224 -2947
IGKV3-11 5548 -7167
IGKV3-15 3174 -4687
IGKV3-20 3704 -5021
IGKV3D-20 -1830 -4618
IGKV4-1 2812 -4988
IGKV5-2 5226 -2682
IGLC1 -2813 -6176
IGLC2 -258 -6539
IGLC3 -2958 -4378
IGLC7 -3403 -4490
IGLV1-36 3522 -5030
IGLV1-40 163 -5497
IGLV1-44 4742 -5791
IGLV1-47 231 -6633
IGLV1-51 1708 -6601
IGLV10-54 -5422 316
IGLV2-11 870 -3205
IGLV2-14 -5127 -8197
IGLV2-18 2015 -2963
IGLV2-23 2029 -4201
IGLV2-8 4818 -5256
IGLV3-1 -96 -5140
IGLV3-12 -7299 -6816
IGLV3-19 4006 -5611
IGLV3-21 -975 -6062
IGLV3-25 -942 -5485
IGLV3-27 -5365 -4834
IGLV4-69 1344 -2261
IGLV5-45 4194 -7364
IGLV6-57 1834 -5837
IGLV7-43 4854 -2823
IGLV7-46 2445 -3619
IGLV8-61 -3989 -5208
MASP2 2089 -6883



Role of LAT2/NTAL/LAB on calcium mobilization

Role of LAT2/NTAL/LAB on calcium mobilization
metric value
setSize 73
pMANOVA 4.31e-14
p.adjustMANOVA 1.78e-12
s.dist 0.329
s.low.CRP 0.23
s.high.CRP -0.236
p.low.CRP 0.000684
p.high.CRP 0.000498




Top 20 genes
Gene low CRP high CRP
IGKV3-11 5548 -7167
IGKV1-33 5955 -6384
IGKV1-16 6217 -5451
IGKV1-5 6127 -5162
IGLV5-45 4194 -7364
IGHV3-23 6032 -5092
IGKV2-30 5205 -5349
IGLV1-44 4742 -5791
IGHV4-59 4532 -5870
SOS1 3534 -7412
IGLV2-8 4818 -5256
IGHV4-39 3786 -6542
IGLV3-19 4006 -5611
IGHV1-2 5956 -3146
IGKV3-20 3704 -5021
IGKC 2773 -6437
IGLV1-36 3522 -5030
IGHV3-11 3518 -4591
IGHV3-7 4185 -3630
IGKV3-15 3174 -4687

Click HERE to show all gene set members

All member genes
low CRP high CRP
FYN -10878 -6729
GAB2 7546 9347
GRB2 9631 9985
IGHE -498 -5753
IGHV1-2 5956 -3146
IGHV1-46 3766 -2976
IGHV1-69 2354 -2328
IGHV2-5 4451 -1972
IGHV2-70 -3315 -2159
IGHV3-11 3518 -4591
IGHV3-13 799 -2451
IGHV3-23 6032 -5092
IGHV3-30 2500 -5193
IGHV3-33 98 -4138
IGHV3-48 3183 -4340
IGHV3-53 3131 -1786
IGHV3-7 4185 -3630
IGHV4-34 1144 -4007
IGHV4-39 3786 -6542
IGHV4-59 4532 -5870
IGKC 2773 -6437
IGKV1-12 725 -6674
IGKV1-16 6217 -5451
IGKV1-17 -241 -2794
IGKV1-33 5955 -6384
IGKV1-5 6127 -5162
IGKV1D-39 5018 -2677
IGKV2-28 1440 -6662
IGKV2-30 5205 -5349
IGKV2D-28 -7224 -2947
IGKV3-11 5548 -7167
IGKV3-15 3174 -4687
IGKV3-20 3704 -5021
IGKV3D-20 -1830 -4618
IGKV4-1 2812 -4988
IGKV5-2 5226 -2682
IGLC1 -2813 -6176
IGLC2 -258 -6539
IGLC3 -2958 -4378
IGLC7 -3403 -4490
IGLV1-36 3522 -5030
IGLV1-40 163 -5497
IGLV1-44 4742 -5791
IGLV1-47 231 -6633
IGLV1-51 1708 -6601
IGLV10-54 -5422 316
IGLV2-11 870 -3205
IGLV2-14 -5127 -8197
IGLV2-18 2015 -2963
IGLV2-23 2029 -4201
IGLV2-8 4818 -5256
IGLV3-1 -96 -5140
IGLV3-12 -7299 -6816
IGLV3-19 4006 -5611
IGLV3-21 -975 -6062
IGLV3-25 -942 -5485
IGLV3-27 -5365 -4834
IGLV4-69 1344 -2261
IGLV5-45 4194 -7364
IGLV6-57 1834 -5837
IGLV7-43 4854 -2823
IGLV7-46 2445 -3619
IGLV8-61 -3989 -5208
LAT2 8582 9705
LYN 7575 8379
PDPK1 2392 7816
PIK3CA 6889 4182
PIK3CB 9838 9248
PIK3R1 -7197 -8942
PIK3R2 2459 5820
SHC1 -3416 5815
SOS1 3534 -7412
SYK 9464 9848



MyD88:MAL(TIRAP) cascade initiated on plasma membrane

MyD88:MAL(TIRAP) cascade initiated on plasma membrane
metric value
setSize 92
pMANOVA 5.35e-14
p.adjustMANOVA 1.97e-12
s.dist 0.566
s.low.CRP 0.315
s.high.CRP 0.47
p.low.CRP 1.75e-07
p.high.CRP 6.24e-15




Top 20 genes
Gene low CRP high CRP
S100A12 10088 10121
CD36 10064 9814
DUSP3 9937 9647
NKIRAS2 9581 9936
MAPK14 9907 9606
APP 9951 9504
IRAK3 9660 9553
CD14 9551 9658
TLR4 9494 9617
TLR2 9930 9118
MAP2K1 9163 9879
MAP2K6 9435 9577
TLR6 9634 9209
TLR1 9828 8868
MAPK3 8931 9626
LY96 9529 8995
PELI2 9242 9060
MAP2K3 8978 9308
NOD2 9408 8613
MEF2A 9000 8162

Click HERE to show all gene set members

All member genes
low CRP high CRP
AGER -1839 3181
APP 9951 9504
ATF1 7833 5463
ATF2 7002 164
BTK 7623 7870
BTRC -6845 -441
CD14 9551 9658
CD36 10064 9814
CHUK 9198 7663
CREB1 4878 -3476
CUL1 -2085 -10951
DUSP3 9937 9647
DUSP4 -6630 -4192
DUSP6 7994 2589
DUSP7 -4748 387
ECSIT 4110 5590
ELK1 -355 3195
FBXW11 4585 7364
FOS 6663 6569
HMGB1 3876 -968
IKBKB -5276 -2118
IKBKG -3058 7903
IRAK1 2444 7601
IRAK2 -11058 -2404
IRAK3 9660 9553
JUN 2838 4810
LY96 9529 8995
MAP2K1 9163 9879
MAP2K3 8978 9308
MAP2K4 6895 7431
MAP2K6 9435 9577
MAP2K7 -2754 4813
MAP3K1 5466 5938
MAP3K7 1546 4274
MAP3K8 -7139 8928
MAPK1 1052 9260
MAPK10 6734 3872
MAPK11 7257 1843
MAPK14 9907 9606
MAPK3 8931 9626
MAPK7 -10125 5069
MAPK8 -1061 -9914
MAPK9 -6530 -1870
MAPKAPK2 -10572 6892
MAPKAPK3 7493 9250
MEF2A 9000 8162
MEF2C 6943 -2868
MYD88 8651 8344
NFKB1 7857 6377
NFKB2 3069 -1167
NFKBIA 6855 7374
NFKBIB -9679 5479
NKIRAS1 2619 689
NKIRAS2 9581 9936
NOD1 -10930 -10348
NOD2 9408 8613
PELI1 9064 5690
PELI2 9242 9060
PELI3 5708 8764
PPP2CA 8810 8328
PPP2CB 8482 7631
PPP2R1A -3087 6994
PPP2R1B 2503 437
PPP2R5D -6508 4985
RELA -7305 2739
RIPK2 1665 2297
RPS27A -3555 -7070
RPS6KA1 -105 9153
RPS6KA2 -5428 3882
RPS6KA3 2859 3437
RPS6KA5 -3980 -11177
S100A12 10088 10121
S100B -8212 -1271
SIGIRR -9900 -8613
SKP1 8120 2700
SOCS1 -219 6051
TAB1 6623 5746
TAB2 9197 5726
TAB3 3912 3647
TIRAP 262 7730
TLR1 9828 8868
TLR2 9930 9118
TLR4 9494 9617
TLR6 9634 9209
TNIP2 -1490 7359
TRAF6 -1767 2089
UBA52 -1875 3023
UBB 8251 6157
UBC -1915 5825
UBE2N 4087 2050
UBE2V1 6665 5995
VRK3 -7245 5798



Toll Like Receptor 2 (TLR2) Cascade

Toll Like Receptor 2 (TLR2) Cascade
metric value
setSize 92
pMANOVA 5.35e-14
p.adjustMANOVA 1.97e-12
s.dist 0.566
s.low.CRP 0.315
s.high.CRP 0.47
p.low.CRP 1.75e-07
p.high.CRP 6.24e-15




Top 20 genes
Gene low CRP high CRP
S100A12 10088 10121
CD36 10064 9814
DUSP3 9937 9647
NKIRAS2 9581 9936
MAPK14 9907 9606
APP 9951 9504
IRAK3 9660 9553
CD14 9551 9658
TLR4 9494 9617
TLR2 9930 9118
MAP2K1 9163 9879
MAP2K6 9435 9577
TLR6 9634 9209
TLR1 9828 8868
MAPK3 8931 9626
LY96 9529 8995
PELI2 9242 9060
MAP2K3 8978 9308
NOD2 9408 8613
MEF2A 9000 8162

Click HERE to show all gene set members

All member genes
low CRP high CRP
AGER -1839 3181
APP 9951 9504
ATF1 7833 5463
ATF2 7002 164
BTK 7623 7870
BTRC -6845 -441
CD14 9551 9658
CD36 10064 9814
CHUK 9198 7663
CREB1 4878 -3476
CUL1 -2085 -10951
DUSP3 9937 9647
DUSP4 -6630 -4192
DUSP6 7994 2589
DUSP7 -4748 387
ECSIT 4110 5590
ELK1 -355 3195
FBXW11 4585 7364
FOS 6663 6569
HMGB1 3876 -968
IKBKB -5276 -2118
IKBKG -3058 7903
IRAK1 2444 7601
IRAK2 -11058 -2404
IRAK3 9660 9553
JUN 2838 4810
LY96 9529 8995
MAP2K1 9163 9879
MAP2K3 8978 9308
MAP2K4 6895 7431
MAP2K6 9435 9577
MAP2K7 -2754 4813
MAP3K1 5466 5938
MAP3K7 1546 4274
MAP3K8 -7139 8928
MAPK1 1052 9260
MAPK10 6734 3872
MAPK11 7257 1843
MAPK14 9907 9606
MAPK3 8931 9626
MAPK7 -10125 5069
MAPK8 -1061 -9914
MAPK9 -6530 -1870
MAPKAPK2 -10572 6892
MAPKAPK3 7493 9250
MEF2A 9000 8162
MEF2C 6943 -2868
MYD88 8651 8344
NFKB1 7857 6377
NFKB2 3069 -1167
NFKBIA 6855 7374
NFKBIB -9679 5479
NKIRAS1 2619 689
NKIRAS2 9581 9936
NOD1 -10930 -10348
NOD2 9408 8613
PELI1 9064 5690
PELI2 9242 9060
PELI3 5708 8764
PPP2CA 8810 8328
PPP2CB 8482 7631
PPP2R1A -3087 6994
PPP2R1B 2503 437
PPP2R5D -6508 4985
RELA -7305 2739
RIPK2 1665 2297
RPS27A -3555 -7070
RPS6KA1 -105 9153
RPS6KA2 -5428 3882
RPS6KA3 2859 3437
RPS6KA5 -3980 -11177
S100A12 10088 10121
S100B -8212 -1271
SIGIRR -9900 -8613
SKP1 8120 2700
SOCS1 -219 6051
TAB1 6623 5746
TAB2 9197 5726
TAB3 3912 3647
TIRAP 262 7730
TLR1 9828 8868
TLR2 9930 9118
TLR4 9494 9617
TLR6 9634 9209
TNIP2 -1490 7359
TRAF6 -1767 2089
UBA52 -1875 3023
UBB 8251 6157
UBC -1915 5825
UBE2N 4087 2050
UBE2V1 6665 5995
VRK3 -7245 5798



Toll Like Receptor TLR1:TLR2 Cascade

Toll Like Receptor TLR1:TLR2 Cascade
metric value
setSize 92
pMANOVA 5.35e-14
p.adjustMANOVA 1.97e-12
s.dist 0.566
s.low.CRP 0.315
s.high.CRP 0.47
p.low.CRP 1.75e-07
p.high.CRP 6.24e-15




Top 20 genes
Gene low CRP high CRP
S100A12 10088 10121
CD36 10064 9814
DUSP3 9937 9647
NKIRAS2 9581 9936
MAPK14 9907 9606
APP 9951 9504
IRAK3 9660 9553
CD14 9551 9658
TLR4 9494 9617
TLR2 9930 9118
MAP2K1 9163 9879
MAP2K6 9435 9577
TLR6 9634 9209
TLR1 9828 8868
MAPK3 8931 9626
LY96 9529 8995
PELI2 9242 9060
MAP2K3 8978 9308
NOD2 9408 8613
MEF2A 9000 8162

Click HERE to show all gene set members

All member genes
low CRP high CRP
AGER -1839 3181
APP 9951 9504
ATF1 7833 5463
ATF2 7002 164
BTK 7623 7870
BTRC -6845 -441
CD14 9551 9658
CD36 10064 9814
CHUK 9198 7663
CREB1 4878 -3476
CUL1 -2085 -10951
DUSP3 9937 9647
DUSP4 -6630 -4192
DUSP6 7994 2589
DUSP7 -4748 387
ECSIT 4110 5590
ELK1 -355 3195
FBXW11 4585 7364
FOS 6663 6569
HMGB1 3876 -968
IKBKB -5276 -2118
IKBKG -3058 7903
IRAK1 2444 7601
IRAK2 -11058 -2404
IRAK3 9660 9553
JUN 2838 4810
LY96 9529 8995
MAP2K1 9163 9879
MAP2K3 8978 9308
MAP2K4 6895 7431
MAP2K6 9435 9577
MAP2K7 -2754 4813
MAP3K1 5466 5938
MAP3K7 1546 4274
MAP3K8 -7139 8928
MAPK1 1052 9260
MAPK10 6734 3872
MAPK11 7257 1843
MAPK14 9907 9606
MAPK3 8931 9626
MAPK7 -10125 5069
MAPK8 -1061 -9914
MAPK9 -6530 -1870
MAPKAPK2 -10572 6892
MAPKAPK3 7493 9250
MEF2A 9000 8162
MEF2C 6943 -2868
MYD88 8651 8344
NFKB1 7857 6377
NFKB2 3069 -1167
NFKBIA 6855 7374
NFKBIB -9679 5479
NKIRAS1 2619 689
NKIRAS2 9581 9936
NOD1 -10930 -10348
NOD2 9408 8613
PELI1 9064 5690
PELI2 9242 9060
PELI3 5708 8764
PPP2CA 8810 8328
PPP2CB 8482 7631
PPP2R1A -3087 6994
PPP2R1B 2503 437
PPP2R5D -6508 4985
RELA -7305 2739
RIPK2 1665 2297
RPS27A -3555 -7070
RPS6KA1 -105 9153
RPS6KA2 -5428 3882
RPS6KA3 2859 3437
RPS6KA5 -3980 -11177
S100A12 10088 10121
S100B -8212 -1271
SIGIRR -9900 -8613
SKP1 8120 2700
SOCS1 -219 6051
TAB1 6623 5746
TAB2 9197 5726
TAB3 3912 3647
TIRAP 262 7730
TLR1 9828 8868
TLR2 9930 9118
TLR4 9494 9617
TLR6 9634 9209
TNIP2 -1490 7359
TRAF6 -1767 2089
UBA52 -1875 3023
UBB 8251 6157
UBC -1915 5825
UBE2N 4087 2050
UBE2V1 6665 5995
VRK3 -7245 5798



Toll Like Receptor TLR6:TLR2 Cascade

Toll Like Receptor TLR6:TLR2 Cascade
metric value
setSize 92
pMANOVA 5.35e-14
p.adjustMANOVA 1.97e-12
s.dist 0.566
s.low.CRP 0.315
s.high.CRP 0.47
p.low.CRP 1.75e-07
p.high.CRP 6.24e-15




Top 20 genes
Gene low CRP high CRP
S100A12 10088 10121
CD36 10064 9814
DUSP3 9937 9647
NKIRAS2 9581 9936
MAPK14 9907 9606
APP 9951 9504
IRAK3 9660 9553
CD14 9551 9658
TLR4 9494 9617
TLR2 9930 9118
MAP2K1 9163 9879
MAP2K6 9435 9577
TLR6 9634 9209
TLR1 9828 8868
MAPK3 8931 9626
LY96 9529 8995
PELI2 9242 9060
MAP2K3 8978 9308
NOD2 9408 8613
MEF2A 9000 8162

Click HERE to show all gene set members

All member genes
low CRP high CRP
AGER -1839 3181
APP 9951 9504
ATF1 7833 5463
ATF2 7002 164
BTK 7623 7870
BTRC -6845 -441
CD14 9551 9658
CD36 10064 9814
CHUK 9198 7663
CREB1 4878 -3476
CUL1 -2085 -10951
DUSP3 9937 9647
DUSP4 -6630 -4192
DUSP6 7994 2589
DUSP7 -4748 387
ECSIT 4110 5590
ELK1 -355 3195
FBXW11 4585 7364
FOS 6663 6569
HMGB1 3876 -968
IKBKB -5276 -2118
IKBKG -3058 7903
IRAK1 2444 7601
IRAK2 -11058 -2404
IRAK3 9660 9553
JUN 2838 4810
LY96 9529 8995
MAP2K1 9163 9879
MAP2K3 8978 9308
MAP2K4 6895 7431
MAP2K6 9435 9577
MAP2K7 -2754 4813
MAP3K1 5466 5938
MAP3K7 1546 4274
MAP3K8 -7139 8928
MAPK1 1052 9260
MAPK10 6734 3872
MAPK11 7257 1843
MAPK14 9907 9606
MAPK3 8931 9626
MAPK7 -10125 5069
MAPK8 -1061 -9914
MAPK9 -6530 -1870
MAPKAPK2 -10572 6892
MAPKAPK3 7493 9250
MEF2A 9000 8162
MEF2C 6943 -2868
MYD88 8651 8344
NFKB1 7857 6377
NFKB2 3069 -1167
NFKBIA 6855 7374
NFKBIB -9679 5479
NKIRAS1 2619 689
NKIRAS2 9581 9936
NOD1 -10930 -10348
NOD2 9408 8613
PELI1 9064 5690
PELI2 9242 9060
PELI3 5708 8764
PPP2CA 8810 8328
PPP2CB 8482 7631
PPP2R1A -3087 6994
PPP2R1B 2503 437
PPP2R5D -6508 4985
RELA -7305 2739
RIPK2 1665 2297
RPS27A -3555 -7070
RPS6KA1 -105 9153
RPS6KA2 -5428 3882
RPS6KA3 2859 3437
RPS6KA5 -3980 -11177
S100A12 10088 10121
S100B -8212 -1271
SIGIRR -9900 -8613
SKP1 8120 2700
SOCS1 -219 6051
TAB1 6623 5746
TAB2 9197 5726
TAB3 3912 3647
TIRAP 262 7730
TLR1 9828 8868
TLR2 9930 9118
TLR4 9494 9617
TLR6 9634 9209
TNIP2 -1490 7359
TRAF6 -1767 2089
UBA52 -1875 3023
UBB 8251 6157
UBC -1915 5825
UBE2N 4087 2050
UBE2V1 6665 5995
VRK3 -7245 5798



Transport to the Golgi and subsequent modification

Transport to the Golgi and subsequent modification
metric value
setSize 155
pMANOVA 7.98e-14
p.adjustMANOVA 2.86e-12
s.dist 0.401
s.low.CRP 0.181
s.high.CRP 0.358
p.low.CRP 9.86e-05
p.high.CRP 1.43e-14




Top 20 genes
Gene low CRP high CRP
F5 10084 10070
SERPINA1 9571 9817
ARF4 9859 9444
SPTB 9958 9302
KDELR1 9552 9681
CD55 9326 9842
RAB1A 9700 9407
CTSZ 8972 9860
NSF 8895 9680
MGAT4B 9276 9187
DCTN2 8504 10012
ANK1 9797 8626
B4GALT5 8862 9469
ARF1 8465 9910
CAPZA2 9698 8474
TGFA 7935 9686
DCTN4 7967 9572
CAPZA1 8666 8511
COPA 7617 9591
TMED7 9038 7918

Click HERE to show all gene set members

All member genes
low CRP high CRP
ACTR10 8589 7569
ACTR1A -2833 8680
ANK1 9797 8626
ANK3 3262 -7407
ANKRD28 -5795 -3898
ARCN1 4082 6402
AREG 4465 7165
ARF1 8465 9910
ARF3 5651 9049
ARF4 9859 9444
ARF5 5736 9180
ARFGAP1 -6136 2991
ARFGAP2 -8987 2096
ARFGAP3 -6040 5157
B4GALT1 -4177 7099
B4GALT2 -7253 -2349
B4GALT3 -9162 -7981
B4GALT4 -9971 3971
B4GALT5 8862 9469
B4GALT6 -10936 -1047
BET1 7030 -4395
BET1L -7832 -2582
CAPZA1 8666 8511
CAPZA2 9698 8474
CAPZB 6100 8926
CD55 9326 9842
CD59 4075 5772
CHST10 -11043 -8384
CHST8 2634 6673
CNIH1 9316 7116
CNIH2 701 601
CNIH3 -8173 -6989
COG1 -10399 -10838
COG2 -1210 -5915
COG3 3891 -5333
COG4 -4813 2002
COG5 1617 -3368
COG6 1512 -6280
COG7 2191 6149
COG8 -2814 2839
COL7A1 3993 7683
COPA 7617 9591
COPB1 8213 7283
COPB2 8531 8034
COPE 365 8719
COPG1 2542 9195
COPG2 7905 8313
COPZ1 2549 5017
COPZ2 -9229 -9247
CSNK1D -10030 6117
CTSC -7528 5285
CTSZ 8972 9860
DCTN1 -5984 7873
DCTN2 8504 10012
DCTN3 325 7904
DCTN4 7967 9572
DCTN5 -7505 664
DCTN6 7871 7759
DYNC1H1 -8881 -2533
DYNC1I1 7141 2722
DYNC1I2 8160 8196
DYNC1LI1 7894 6997
DYNC1LI2 3494 5636
DYNLL1 6026 6499
DYNLL2 -6325 -225
F5 10084 10070
F8 7498 7167
FUCA1 8013 8533
FUT8 -7539 -7706
GBF1 -8933 1807
GOLGA2 -878 8019
GOLGB1 -242 -5768
GORASP1 7651 6560
GOSR1 -4021 2971
GOSR2 -2437 1468
KDELR1 9552 9681
KDELR2 8771 7531
KDELR3 2255 -3318
LMAN1 -1255 -10522
LMAN2 2397 8522
LMAN2L 7675 6680
MAN1A1 4965 9297
MAN1A2 -1459 -993
MAN1C1 1436 -8761
MAN2A1 5542 -2948
MAN2A2 1864 8354
MANEA 6711 -5721
MCFD2 7963 7485
MGAT1 2229 8361
MGAT2 -5319 4067
MGAT3 2892 -5080
MGAT4A -3305 -4301
MGAT4B 9276 9187
MGAT4C 3599 -4032
MGAT5 -5440 -102
MIA2 6640 5566
MIA3 3397 -6425
NAPA -2447 3305
NAPB -291 -2004
NAPG 7409 3591
NSF 8895 9680
PPP6C 8559 6316
PPP6R1 -5320 7658
PPP6R3 3008 3925
PREB -1638 8142
RAB1A 9700 9407
RAB1B 5676 9455
SAR1B 8795 5984
SCFD1 4551 3924
SEC13 2125 6861
SEC16A -2929 6748
SEC16B -1454 1213
SEC22A 374 -4424
SEC22B 8663 4943
SEC22C -2377 -1611
SEC23A 8776 6905
SEC23IP 5231 -574
SEC24A 8318 7788
SEC24B 1663 5398
SEC24C -9662 3561
SEC24D 8017 8795
SEC31A 1743 2474
SERPINA1 9571 9817
SPTA1 9470 6216
SPTAN1 -10174 -8889
SPTB 9958 9302
SPTBN1 -6572 -6164
SPTBN2 -5447 -3871
SPTBN5 -7557 -461
ST3GAL4 -9921 7993
ST6GAL1 -10673 -10107
ST8SIA6 -10982 -6606
STX17 -4480 -10772
STX5 3566 8258
TBC1D20 -6556 3818
TFG 8930 6725
TGFA 7935 9686
TMED10 35 2168
TMED2 6426 6360
TMED3 -2098 4751
TMED7 9038 7918
TMED9 917 9007
TMEM115 31 6881
TRAPPC1 5277 9110
TRAPPC10 -10478 -2812
TRAPPC2 -8890 -5344
TRAPPC2L -350 -932
TRAPPC3 6827 7922
TRAPPC4 -7161 -2663
TRAPPC5 4081 6280
TRAPPC6A -7665 -10218
TRAPPC6B 6230 4019
TRAPPC9 921 7473
USO1 6916 3905
YKT6 -3724 6818



Clathrin-mediated endocytosis

Clathrin-mediated endocytosis
metric value
setSize 125
pMANOVA 8.48e-14
p.adjustMANOVA 2.96e-12
s.dist 0.45
s.low.CRP 0.208
s.high.CRP 0.399
p.low.CRP 6.07e-05
p.high.CRP 1.32e-14




Top 20 genes
Gene low CRP high CRP
VAMP7 10053 10044
GRB2 9631 9985
ITSN1 9969 9600
AGFG1 10023 9542
CLTCL1 10011 9218
CLTC 9376 9720
PICALM 9406 9673
ARPC5 9301 9174
ARPC1A 8875 9605
TGOLN2 8606 9683
FNBP1L 9365 8493
EGF 9244 8355
TGFA 7935 9686
VAMP3 9204 8284
CLTA 8416 8998
ARPC3 8430 8946
RAB5C 7846 9422
ARRB2 7827 9274
AP2M1 7742 9334
FCHO2 8546 8432

Click HERE to show all gene set members

All member genes
low CRP high CRP
AAK1 -9118 -5763
ACTR2 8743 7962
ACTR3 8622 7832
ADRB2 -11122 -7027
AGFG1 10023 9542
AMPH 6181 9351
AP2A1 -3194 9104
AP2A2 3196 9217
AP2B1 -9145 2444
AP2M1 7742 9334
AP2S1 7422 8877
AREG 4465 7165
ARF6 -2986 3785
ARFGAP1 -6136 2991
ARPC1A 8875 9605
ARPC2 5327 8212
ARPC3 8430 8946
ARPC4 4637 8915
ARPC5 9301 9174
ARRB1 -4581 4541
ARRB2 7827 9274
AVPR2 1919 -154
BIN1 -9734 -10132
CBL 6620 8302
CD3D -9569 -10471
CD3G -9054 -10504
CD4 3147 -5743
CLTA 8416 8998
CLTB -2857 8274
CLTC 9376 9720
CLTCL1 10011 9218
COPS2 8864 5037
COPS3 7364 5716
COPS4 1748 2715
COPS5 3882 5135
COPS6 -3920 4485
COPS7A 1707 8090
COPS7B -9179 -6481
COPS8 -1206 -8494
CTTN 7016 6516
DAB2 3735 9712
DNAJC6 6237 4061
DNM1 6883 3239
DNM2 -6816 8202
DNM3 7927 7198
DVL2 -10305 -7147
EGF 9244 8355
EPN1 5120 9372
EPN2 -6096 -1735
EPS15 6185 4175
EPS15L1 -8354 6665
EREG -837 3226
FCHO1 -3203 -76
FCHO2 8546 8432
FNBP1 -6673 3651
FNBP1L 9365 8493
FZD4 -10858 -7985
GAK -5204 6408
GAPVD1 7396 7396
GPS1 -8718 1571
GRB2 9631 9985
GRK2 757 7818
GRK3 8742 6150
HBEGF 5089 5189
HGS -381 6840
HIP1 5859 9044
HIP1R -8953 -9087
HSPA8 -8286 -8908
IGF2R -1133 9240
IL7R -4956 -11140
ITSN1 9969 9600
ITSN2 7119 5093
KIAA0319 -1650 3716
LDLR 2463 6531
LDLRAP1 -668 -10304
LRP2 964 1845
M6PR -7566 -3638
NECAP1 5273 2539
NECAP2 2916 4382
NEDD8 -156 8587
OCRL 7540 6631
PACSIN1 -11257 -11175
PACSIN2 8024 8785
PICALM 9406 9673
PIK3C2A 1258 -5821
PIP5K1C -4447 6435
RAB5A 8478 6815
RAB5B 3295 7820
RAB5C 7846 9422
REPS1 -7182 -2813
REPS2 7607 8723
RPS27A -3555 -7070
SCARB2 7273 5044
SH3GL1 4634 8807
SH3KBP1 4345 7311
SLC2A8 -10538 -9148
SNX18 -1909 8980
SNX9 -1545 1119
STAM 3046 2017
STAM2 8115 5912
STON1 3492 2681
STON2 2975 4565
SYNJ1 5518 6949
SYNJ2 -6592 -7005
SYT1 6818 4381
SYT11 -10523 504
SYT2 -9931 3980
TF 1794 1244
TFRC 2181 1526
TGFA 7935 9686
TGOLN2 8606 9683
TOR1A 7721 8423
TOR1B -8940 1768
TRIP10 6573 1072
UBA52 -1875 3023
UBB 8251 6157
UBC -1915 5825
UBQLN1 5050 5353
UBQLN2 7704 5498
VAMP2 -9677 -10779
VAMP3 9204 8284
VAMP4 7662 1445
VAMP7 10053 10044
VAMP8 2890 6767
WASL 899 1391



Signaling by Rho GTPases

Signaling by Rho GTPases
metric value
setSize 364
pMANOVA 9.12e-14
p.adjustMANOVA 3.11e-12
s.dist 0.269
s.low.CRP 0.129
s.high.CRP 0.236
p.low.CRP 2.29e-05
p.high.CRP 1.15e-14




Top 20 genes
Gene low CRP high CRP
S100A9 10110 10116
WASF1 10091 10132
S100A8 10041 10093
RHOT1 10010 9811
ARHGEF11 9867 9882
YWHAG 9658 9994
CTNNA1 9646 10004
CYFIP1 9724 9912
GRB2 9631 9985
ITSN1 9969 9600
NCF4 9697 9856
MAPK14 9907 9606
H2BC21 9852 9656
NCF2 9748 9694
YWHAE 9721 9563
ARPC1B 9259 10026
H2AJ 8999 10117
PRKCD 9393 9642
ACTB 9310 9714
FGD4 9557 9414

Click HERE to show all gene set members

All member genes
low CRP high CRP
A2M -7113.0 -9795.0
ABI1 6692.0 7709.0
ABI2 -7512.0 -9823.0
ABL1 -6354.0 4467.0
ABR -802.0 8322.0
ACTB 9310.0 9714.0
ACTG1 7674.0 9499.0
ACTR2 8743.0 7962.0
ACTR3 8622.0 7832.0
AHCTF1 -1588.0 -103.0
AKAP13 -5210.0 6504.0
AR 5214.0 4808.0
ARAP1 5889.0 9116.0
ARAP2 -10793.0 -9493.0
ARAP3 8166.0 8842.0
ARHGAP1 -6103.0 7166.0
ARHGAP10 -7030.0 -6799.0
ARHGAP11A -974.0 3630.0
ARHGAP11B -8078.0 -4887.0
ARHGAP12 -5976.0 -5138.0
ARHGAP15 2604.0 228.0
ARHGAP17 -1419.0 -6569.0
ARHGAP18 9413.0 9465.0
ARHGAP19 7045.0 8536.0
ARHGAP21 6417.0 5320.0
ARHGAP22 4519.0 933.0
ARHGAP23 5840.0 6406.0
ARHGAP24 9246.0 7161.0
ARHGAP25 -10783.0 -521.0
ARHGAP26 7037.0 9592.0
ARHGAP27 -2132.0 7974.0
ARHGAP28 4513.0 2360.0
ARHGAP29 8334.0 8767.0
ARHGAP30 -4879.0 7113.0
ARHGAP31 6008.0 5748.0
ARHGAP32 6102.0 1745.0
ARHGAP33 -4849.0 -4707.0
ARHGAP35 -6993.0 1378.0
ARHGAP39 -5234.0 -7094.0
ARHGAP4 -6109.0 5209.0
ARHGAP42 -6566.0 -6230.0
ARHGAP44 2879.0 -666.0
ARHGAP5 3110.0 -10804.0
ARHGAP6 8128.0 8211.0
ARHGAP8 -11053.0 -10525.0
ARHGAP9 -1609.0 8482.0
ARHGDIA -2208.0 7927.0
ARHGDIB 7840.0 9497.0
ARHGEF1 -7319.0 -1527.0
ARHGEF10 -1806.0 -3987.0
ARHGEF10L 2548.0 -8075.0
ARHGEF11 9867.0 9882.0
ARHGEF12 -213.0 4295.0
ARHGEF17 6839.0 7119.0
ARHGEF18 -8526.0 -2076.0
ARHGEF19 -7958.0 -7166.0
ARHGEF2 1813.0 8144.0
ARHGEF26 -935.0 -4211.0
ARHGEF3 -10835.0 -9026.0
ARHGEF35 -2738.0 -4268.0
ARHGEF38 -5101.0 -2757.0
ARHGEF39 -9494.0 -9574.0
ARHGEF4 3629.0 -8573.0
ARHGEF40 8982.0 9475.0
ARHGEF5 -3592.0 -6792.0
ARHGEF6 4831.0 2908.0
ARHGEF7 -7925.0 1165.0
ARHGEF9 -10987.0 -10693.0
ARPC1A 8875.0 9605.0
ARPC1B 9259.0 10026.0
ARPC2 5327.0 8212.0
ARPC3 8430.0 8946.0
ARPC4 4637.0 8915.0
ARPC5 9301.0 9174.0
AURKB -4097.0 3408.0
B9D2 8167.0 8798.0
BAIAP2 2620.0 -682.0
BCR -10286.0 261.0
BIRC5 2725.0 4169.0
BRK1 5522.0 8298.0
BTK 7623.0 7870.0
BUB1 5839.0 1925.0
BUB1B 3929.0 2104.0
BUB3 -7777.0 -10711.0
CALM1 -6645.0 1321.0
CDC20 -74.0 5136.0
CDC42 8498.0 7640.0
CDCA8 -4836.0 412.0
CDH1 -10697.0 -8067.0
CDKN1B -9926.0 -2672.0
CENPA 3195.0 4228.0
CENPC -8807.0 -11097.0
CENPE -3467.0 886.0
CENPF -1889.0 3258.0
CENPH -3269.0 -8735.0
CENPI -2474.0 -2641.0
CENPK -2160.0 -9816.0
CENPL -10630.0 -8812.0
CENPM 1385.0 -7204.0
CENPN 4436.0 -1101.0
CENPO -10840.0 3129.0
CENPP -10848.0 -8710.0
CENPQ -911.0 -6285.0
CENPT -7579.0 -8354.0
CENPU -4192.0 -6597.0
CFL1 5851.0 9242.0
CHN1 -1913.0 -7969.0
CHN2 5740.0 4836.0
CIT -7580.0 -2898.0
CKAP5 -6411.0 -2392.0
CLASP1 -9685.0 4156.0
CLASP2 2388.0 -1797.0
CLIP1 9515.0 8973.0
CTNNA1 9646.0 10004.0
CTNNB1 3201.0 7613.0
CTTN 7016.0 6516.0
CYBA -48.0 8901.0
CYBB 9900.0 8910.0
CYFIP1 9724.0 9912.0
CYFIP2 -10558.0 -4935.0
DAAM1 4929.0 3983.0
DEPDC1B 554.0 2004.0
DEPDC7 3901.0 -483.0
DIAPH1 -9216.0 4270.0
DIAPH2 9067.0 9290.0
DIAPH3 6644.0 3344.0
DLC1 6410.0 9330.0
DLG4 9905.0 8876.0
DSN1 -8825.0 -8996.0
DVL1 -1093.0 1894.0
DVL2 -10305.0 -7147.0
DVL3 -4437.0 8389.0
DYNC1H1 -8881.0 -2533.0
DYNC1I1 7141.0 2722.0
DYNC1I2 8160.0 8196.0
DYNC1LI1 7894.0 6997.0
DYNC1LI2 3494.0 5636.0
DYNLL1 6026.0 6499.0
DYNLL2 -6325.0 -225.0
ECT2 7940.0 4902.0
ERCC6L 2328.0 -1028.0
EVL -10613.0 -11193.0
FAM13A 9663.0 5971.0
FAM13B -7815.0 -7976.0
FGD2 1340.0 6311.0
FGD3 -6445.0 5799.0
FGD4 9557.0 9414.0
FLNA -8145.0 4196.0
FMNL1 -7128.0 6527.0
FMNL2 -9177.0 -556.0
FMNL3 -11025.0 -9852.0
GDI1 2059.0 7275.0
GDI2 8206.0 7892.0
GMIP 3917.0 9152.0
GNA13 5622.0 6234.0
GOPC -3131.0 -9251.0
GRB2 9631.0 9985.0
H2AC20 -790.0 6112.0
H2AC6 8700.0 8169.0
H2AJ 8999.0 10117.0
H2AZ1 1779.0 7321.0
H2AZ2 -4042.0 2210.0
H2BC11 8424.0 8288.0
H2BC12 9066.0 9812.0
H2BC15 3036.0 6455.0
H2BC17 7882.0 7312.0
H2BC21 9852.0 9656.0
H2BC4 7156.0 7805.0
H2BC5 7596.0 8773.0
H2BC9 7965.0 4715.0
H2BU1 -6349.0 -3895.0
H3-3A 9297.0 9034.0
H3C15 5262.5 7402.5
INCENP -9437.0 323.0
INPP5B -5371.0 -4931.0
IQGAP1 7310.0 9366.0
IQGAP2 6198.0 7948.0
IQGAP3 3938.0 3957.0
ITGB1 3360.0 -108.0
ITGB3BP -458.0 -8029.0
ITSN1 9969.0 9600.0
KALRN 999.0 -4389.0
KDM1A -6245.0 -6064.0
KDM4C -9638.0 -6288.0
KIF14 1714.0 3512.0
KIF18A -5118.0 -1862.0
KIF2A 2515.0 -1329.0
KIF2C 2032.0 104.0
KIF5A -7037.0 -7903.0
KIF5B 9540.0 8103.0
KLC1 1745.0 7386.0
KLC2 -6674.0 -7322.0
KLC3 8390.0 7398.0
KLC4 -9223.0 -3527.0
KLK2 7104.0 1104.0
KNL1 -1431.0 -91.0
KNTC1 -224.0 -8592.0
KTN1 7536.0 1922.0
LIMK1 -2747.0 6617.0
LIMK2 8349.0 8299.0
LIN7B -5596.0 -560.0
MAD1L1 -7936.0 -748.0
MAD2L1 -1797.0 -8340.0
MAPK1 1052.0 9260.0
MAPK11 7257.0 1843.0
MAPK14 9907.0 9606.0
MAPK3 8931.0 9626.0
MAPRE1 8382.0 7653.0
MCF2 -3103.0 3888.0
MCF2L 1063.0 -9438.0
MEN1 -8589.0 -4575.0
MIS12 -6139.0 -10061.0
MRTFA 7793.0 9266.0
MYH10 -7101.0 3044.0
MYH11 1903.0 -4778.0
MYH9 1879.0 8348.0
MYL12B -2612.0 6816.0
MYL6 6786.0 9643.0
MYL9 9640.0 7741.0
MYLK 8091.0 6661.0
MYO9A -6991.0 -7861.0
MYO9B 513.0 8592.0
NCF1 8576.0 7083.0
NCF2 9748.0 9694.0
NCF4 9697.0 9856.0
NCK1 -9250.0 -9113.0
NCKAP1 6871.0 8168.0
NCKAP1L 3966.0 9566.0
NCKIPSD 957.0 1858.0
NCOA2 -4443.0 3788.0
NDC80 -4016.0 -9035.0
NDE1 2098.0 4048.0
NDEL1 5664.0 8515.0
NET1 -5084.0 -7146.0
NF2 -9157.0 -819.0
NOXA1 -2600.0 -5589.0
NSL1 6939.0 5555.0
NUDC -2705.0 2609.0
NUF2 -4390.0 -3313.0
NUP107 -4463.0 -10317.0
NUP133 -4339.0 -4616.0
NUP160 -2518.0 -10020.0
NUP37 3188.0 3613.0
NUP43 -55.0 -10161.0
NUP85 1119.0 -2732.0
NUP98 208.0 4310.0
OBSCN -1198.0 -8212.0
OCRL 7540.0 6631.0
OPHN1 -2899.0 180.0
PAFAH1B1 -336.0 6894.0
PAK1 9711.0 7682.0
PAK2 9019.0 8433.0
PAK3 -1134.0 -4249.0
PDPK1 2392.0 7816.0
PFN1 -5663.0 7801.0
PFN2 5971.0 -5360.0
PIK3C3 6605.0 573.0
PIK3R2 2459.0 5820.0
PIK3R4 -267.0 -2209.0
PIN1 -9660.0 3728.0
PKN1 -10294.0 5192.0
PKN2 6764.0 -3104.0
PKN3 -6719.0 -1067.0
PLEKHG2 6397.0 8532.0
PLEKHG5 142.0 -10045.0
PLK1 -235.0 4265.0
PMF1 3040.0 4375.0
PPP1CB 8657.0 6666.0
PPP1CC 9200.0 4868.0
PPP1R12A 5601.0 6368.0
PPP1R12B -4326.0 4036.0
PPP1R14A 7499.0 7460.0
PPP2CA 8810.0 8328.0
PPP2CB 8482.0 7631.0
PPP2R1A -3087.0 6994.0
PPP2R1B 2503.0 437.0
PPP2R5A -903.0 6957.0
PPP2R5B 5288.0 7952.0
PPP2R5C -10420.0 -7112.0
PPP2R5D -6508.0 4985.0
PPP2R5E 715.0 540.0
PRC1 -5431.0 2601.0
PREX1 -6574.0 8855.0
PRKCA 2473.0 1229.0
PRKCB 5395.0 8378.0
PRKCD 9393.0 9642.0
PRKCZ -10855.0 -7708.0
PTK2 7786.0 3481.0
RAC1 9052.0 9614.0
RAC2 -7677.0 6828.0
RAC3 -4395.0 -1033.0
RACGAP1 3340.0 3770.0
RALBP1 6092.0 7629.0
RANBP2 4453.0 -2222.0
RANGAP1 -10259.0 -9220.0
RASGRF2 -4591.0 -10584.0
RCC2 -6741.0 -781.0
RHOA 8351.0 8888.0
RHOB -4807.0 3859.0
RHOBTB1 9208.0 7887.0
RHOBTB2 -8154.0 -1237.0
RHOC -11158.0 -4627.0
RHOF -11160.0 -10418.0
RHOG 7549.0 9255.0
RHOH -6870.0 -9730.0
RHOQ 9504.0 6692.0
RHOT1 10010.0 9811.0
RHOT2 -6252.0 -2090.0
RHOU 7924.0 9743.0
RHPN1 2265.0 -8079.0
RHPN2 -2702.0 -4003.0
ROCK1 8315.0 7930.0
ROCK2 7628.0 6719.0
RPS27 -9041.0 -7909.0
RTKN -11144.0 -10917.0
S100A8 10041.0 10093.0
S100A9 10110.0 10116.0
SCAI -420.0 -7606.0
SEC13 2125.0 6861.0
SEH1L 7189.0 -8511.0
SFN -918.0 1127.0
SGO1 -7321.0 -4581.0
SGO2 285.0 -3804.0
SKA1 4635.0 1882.0
SKA2 -7953.0 -5579.0
SOS1 3534.0 -7412.0
SOS2 9141.0 8628.0
SPC24 -1637.0 3696.0
SPDL1 -8869.0 -10380.0
SRC -6857.0 -7229.0
SRF 4035.0 7760.0
SRGAP1 6525.0 7219.0
SRGAP2 4493.0 7351.0
SRGAP3 -4761.0 -4198.0
STARD13 -2011.0 5301.0
STARD8 848.0 4743.0
SYDE2 7572.0 -7169.0
TAGAP -10622.0 -11214.0
TAOK1 5604.0 6063.0
TAX1BP3 8203.0 8751.0
TIAM1 5732.0 -809.0
TIAM2 -10122.0 -8001.0
TRIO -2029.0 3636.0
TRIP10 6573.0 1072.0
VAV1 5553.0 8731.0
VAV2 -5033.0 -1339.0
VAV3 -6160.0 7203.0
WAS 8258.0 9323.0
WASF1 10091.0 10132.0
WASF2 7535.0 9576.0
WASF3 8142.0 7240.0
WASL 899.0 1391.0
WIPF1 -5700.0 3866.0
WIPF2 2722.0 7125.0
XPO1 6563.0 -3235.0
YWHAB 8274.0 6101.0
YWHAE 9721.0 9563.0
YWHAG 9658.0 9994.0
YWHAH 9519.0 9189.0
YWHAQ -9021.0 -1643.0
YWHAZ 5165.0 5861.0
ZW10 5778.0 -752.0
ZWILCH -9080.0 -10492.0
ZWINT -1751.0 -5219.0



Developmental Biology

Developmental Biology
metric value
setSize 726
pMANOVA 1.61e-13
p.adjustMANOVA 5.35e-12
s.dist 0.179
s.low.CRP 0.0723
s.high.CRP 0.163
p.low.CRP 0.000906
p.high.CRP 6.48e-14




Top 20 genes
Gene low CRP high CRP
PPARG 10111 10137
GRB10 10103 10040
NUMB 10040 10006
PRKACA 9885 10068
CD36 10064 9814
ST14 10019 9752
ARHGEF11 9867 9882
LAMC1 9628 10118
DSC2 9739 9923
CTNNA1 9646 10004
SDCBP 9944 9687
GRB2 9631 9985
ALCAM 9621 9950
ITSN1 9969 9600
FES 9556 9967
MAPK14 9907 9606
H2BC21 9852 9656
NCSTN 9503 9869
PLXNC1 9678 9690
ZNF467 9518 9772

Click HERE to show all gene set members

All member genes
low CRP high CRP
ABL1 -6354.0 4467.0
ABL2 5121.0 4415.0
ABLIM1 -4928.0 -10710.0
ABLIM2 -8230.0 -8500.0
ABLIM3 9567.0 8720.0
ACTB 9310.0 9714.0
ACTG1 7674.0 9499.0
ACTR2 8743.0 7962.0
ACTR3 8622.0 7832.0
ACVR1B 9048.0 9961.0
ACVR1C 3243.0 -10245.0
ACVR2A -7204.0 -11003.0
ACVR2B -6617.0 -10642.0
ADAM10 9314.0 9481.0
ADAM11 -8710.0 -6749.0
ADAM22 -9347.0 -9920.0
ADAM23 -4315.0 -10372.0
ADGRG6 -9475.0 -8018.0
ADGRV1 4934.0 3570.0
AGAP2 -10865.0 1136.0
AGRN -9794.0 -10649.0
AJUBA -1981.0 -8712.0
AKAP5 -11075.0 -11060.0
AKT1 -4794.0 6231.0
AKT2 -8391.0 5504.0
AKT3 -9616.0 -10833.0
ALCAM 9621.0 9950.0
ANGPTL4 -7923.0 824.0
ANK1 9797.0 8626.0
ANK3 3262.0 -7407.0
AP2A1 -3194.0 9104.0
AP2A2 3196.0 9217.0
AP2B1 -9145.0 2444.0
AP2M1 7742.0 9334.0
AP2S1 7422.0 8877.0
APH1A -3379.0 6321.0
APH1B 6306.0 6678.0
ARHGAP35 -6993.0 1378.0
ARHGAP39 -5234.0 -7094.0
ARHGEF11 9867.0 9882.0
ARHGEF12 -213.0 4295.0
ARHGEF28 -10356.0 -6123.0
ARHGEF7 -7925.0 1165.0
ARPC1A 8875.0 9605.0
ARPC1B 9259.0 10026.0
ARPC2 5327.0 8212.0
ARPC3 8430.0 8946.0
ARPC4 4637.0 8915.0
ARPC5 9301.0 9174.0
ASH2L 2845.0 6972.0
BNIP2 9872.0 8411.0
CACNA1C -10151.0 -8799.0
CACNA1D 7066.0 2211.0
CACNA1H -4197.0 -9600.0
CACNA1I 4970.0 -9152.0
CACNB1 -9825.0 -8459.0
CACNB2 -931.0 -6046.0
CACNB3 -359.0 1459.0
CACNB4 1752.0 -8441.0
CACNG8 -6881.0 -7478.0
CAP1 8192.0 8530.0
CAPN1 7094.0 9770.0
CAPNS1 5468.0 8812.0
CARM1 9361.0 9442.0
CASC3 -6012.0 6784.0
CBFB 3639.0 2677.0
CCNC 7860.0 -2135.0
CCND3 -1611.0 8856.0
CD24 8072.0 1764.0
CD36 10064.0 9814.0
CD72 -5736.0 -3306.0
CDC42 8498.0 7640.0
CDH4 -5064.0 -4840.0
CDK19 6602.0 9278.0
CDK2 -5388.0 -2127.0
CDK4 -9596.0 -8845.0
CDK5 8395.0 9380.0
CDK5R1 -8396.0 3375.0
CDK8 -3688.0 1375.0
CDKN1A 3621.0 5190.0
CDON -432.0 -9157.0
CEBPA 7798.0 9188.0
CEBPB 4182.0 9158.0
CEBPD 8134.0 9779.0
CEBPE 9405.0 6890.0
CFL1 5851.0 9242.0
CHD9 -4184.0 -2634.0
CHL1 -5907.0 -3090.0
CLASP1 -9685.0 4156.0
CLASP2 2388.0 -1797.0
CLTA 8416.0 8998.0
CLTB -2857.0 8274.0
CLTC 9376.0 9720.0
CLTCL1 10011.0 9218.0
CNOT6 5568.0 5436.0
CNTN2 -7275.0 3012.0
CNTNAP1 -910.0 -6344.0
COL4A2 1717.0 838.0
COL4A3 -2340.0 -3206.0
COL4A4 611.0 -3693.0
COL6A1 5798.0 -5980.0
COL6A2 -10166.0 -7673.0
COL6A3 8421.0 3878.0
COL9A2 -10833.0 -5976.0
COL9A3 8252.0 4215.0
CREB1 4878.0 -3476.0
CREBBP -4951.0 6023.0
CRMP1 -3102.0 793.0
CSF3R 9184.0 9098.0
CSNK2A1 3192.0 8248.0
CSNK2A2 6050.0 7886.0
CSNK2B 1222.0 5287.0
CSTA 9816.0 9065.0
CTCF -6589.0 -6463.0
CTNNA1 9646.0 10004.0
CTNNB1 3201.0 7613.0
CUL2 6801.0 1682.0
CXCR4 -3561.0 1966.0
CYP51A1 7585.0 6990.0
DAB1 -4277.0 -10941.0
DAG1 -8464.0 -2147.0
DEK 7282.0 955.0
DLG1 -295.0 -8414.0
DLG3 -10680.0 -10374.0
DLG4 9905.0 8876.0
DNM1 6883.0 3239.0
DNM2 -6816.0 8202.0
DNM3 7927.0 7198.0
DOCK1 6941.0 8390.0
DOK1 5984.0 9447.0
DOK2 -8963.0 4141.0
DOK4 -5798.0 4901.0
DOK6 -5672.0 -7235.0
DPPA4 -3708.0 380.0
DPYSL2 9075.0 8993.0
DPYSL4 -1716.0 -7739.0
DRAP1 -10374.0 264.0
DSC1 2498.0 -9997.0
DSC2 9739.0 9923.0
DSP -2099.0 -1252.0
E2F1 6782.0 6864.0
EBF1 -1954.0 -6085.0
EED -4507.0 -6867.0
EFNA1 6312.0 1360.0
EFNA3 -5772.0 -6586.0
EFNA4 6979.0 6434.0
EFNA5 -10204.0 -4406.0
EFNB1 -10577.0 -5714.0
EGR2 2394.0 -4615.0
EIF4A3 7867.0 7462.0
EIF4G1 6261.0 9336.0
ELOB 4867.0 8716.0
ELOC 6598.0 8484.0
ENAH -3230.0 -1566.0
EOMES -11115.0 -9186.0
EP300 4311.0 7552.0
EPAS1 5959.0 8551.0
EPHA1 1116.0 -7965.0
EPHA2 -11259.0 -9827.0
EPHA4 -9580.0 -11031.0
EPHB1 -10575.0 -6014.0
EPHB2 8557.0 2660.0
EPHB3 9306.0 8635.0
EPHB4 8949.0 3326.0
EPHB6 3977.0 -679.0
ERBB2 -11251.0 -9287.0
ETF1 8721.0 7223.0
EVL -10613.0 -11193.0
EVPL 2613.0 -2052.0
EZH2 -4248.0 -9643.0
EZR -11094.0 -6256.0
FAM120B -1528.0 3105.0
FARP2 -3116.0 -8946.0
FAU -5297.0 2810.0
FES 9556.0 9967.0
FGF2 5967.0 3177.0
FGFR1 -8719.0 -822.0
FLI1 -1019.0 7856.0
FOXO1 -4402.0 -9319.0
FOXO3 8202.0 9854.0
FOXP1 -4435.0 -8213.0
FRS2 1765.0 -3137.0
FURIN 8111.0 10053.0
FYN -10878.0 -6729.0
GAB1 7926.0 5272.0
GAB2 7546.0 9347.0
GATA2 -5266.0 -9369.0
GATA6 -10906.0 -9307.0
GCK 1371.0 1141.0
GFI1 -11137.0 -7988.0
GFRA2 -9183.0 -5056.0
GIT1 -9746.0 -4400.0
GPC1 -6229.0 -1709.0
GRB10 10103.0 10040.0
GRB2 9631.0 9985.0
GSK3B 6119.0 7526.0
GSPT1 9380.0 4598.0
GSPT2 -8427.0 -8216.0
H2AC20 -790.0 6112.0
H2AC6 8700.0 8169.0
H2AJ 8999.0 10117.0
H2AZ1 1779.0 7321.0
H2AZ2 -4042.0 2210.0
H2BC11 8424.0 8288.0
H2BC12 9066.0 9812.0
H2BC15 3036.0 6455.0
H2BC17 7882.0 7312.0
H2BC21 9852.0 9656.0
H2BC4 7156.0 7805.0
H2BC5 7596.0 8773.0
H2BC9 7965.0 4715.0
H2BU1 -6349.0 -3895.0
H3-3A 9297.0 9034.0
H3C15 5262.5 7402.5
HDAC2 8973.0 3999.0
HDAC3 1719.0 6319.0
HELZ2 -10464.0 -4663.0
HES1 -10141.0 -3420.0
HHEX 8016.0 7831.0
HIF3A -7283.0 927.0
HMGCR 8736.0 8314.0
HOXA1 -10211.0 -4310.0
HOXA3 -9367.0 -3084.0
HOXB2 -8531.0 -7446.0
HOXB3 -9299.0 -9624.0
HOXB4 -10702.0 -7573.0
HOXC4 -10650.0 -7016.0
HRAS -2248.0 -1932.0
HSP90AA1 5309.0 410.0
HSP90AB1 2247.0 -6319.0
HSPA8 -8286.0 -8908.0
IL6R 9360.0 8189.0
IRS2 8141.0 9618.0
ITGA1 9674.0 8579.0
ITGA10 5196.0 -2609.0
ITGA2 8852.0 -28.0
ITGA2B 9720.0 9409.0
ITGA5 6141.0 8618.0
ITGA9 8784.0 6204.0
ITGAV 7467.0 6188.0
ITGB1 3360.0 -108.0
ITGB3 9450.0 8690.0
ITSN1 9969.0 9600.0
JUN 2838.0 4810.0
JUP -4305.0 -4960.0
KALRN 999.0 -4389.0
KAT2A -6742.0 -10405.0
KAT2B 116.0 -1532.0
KAZN 3987.0 6564.0
KDM6A -3419.0 5092.0
KIF4A -1703.0 4331.0
KLF4 -1078.0 1442.0
KLF5 7000.0 4085.0
KLK14 2908.0 -3018.0
KMT2A -7831.0 -9216.0
KMT2C -769.0 1736.0
KMT2D -2369.0 5062.0
KRAS 3789.0 4070.0
KRT1 6823.0 4687.0
KRT10 -1627.0 3073.0
KRT15 -6750.0 -7375.0
KRT18 -4275.0 -2612.0
KRT23 5942.0 6691.0
KRT5 -11153.0 -9242.0
KRT7 4826.0 6483.0
KRT72 -3847.0 -6835.0
KRT73 -4336.0 -6335.0
KRT8 -187.0 2355.0
KRT80 3000.0 7556.0
KRTAP5-1 -8927.0 -7949.0
L1CAM -1885.0 -5908.0
LAMA1 1937.0 -1809.0
LAMA2 -10568.0 -6239.0
LAMB1 2797.0 7716.0
LAMC1 9628.0 10118.0
LDB1 -9483.0 -4542.0
LEF1 4722.0 -10841.0
LEFTY1 -6425.0 -1725.0
LGI2 8572.0 5131.0
LGI4 -2719.0 -2568.0
LHX4 -4253.0 -7171.0
LIMK1 -2747.0 6617.0
LIMK2 8349.0 8299.0
LIN28A 3714.0 434.0
LIPN 679.0 7124.0
LPL -2018.0 4002.0
LYN 7575.0 8379.0
LYPLA2 -251.0 8654.0
MAFB 8323.0 8486.0
MAGOH -2342.0 3842.0
MAGOHB -1581.0 -9521.0
MAML1 -81.0 7084.0
MAML2 3788.0 -1483.0
MAML3 9463.0 9534.0
MAMLD1 -532.0 -6686.0
MAP2K1 9163.0 9879.0
MAP2K2 185.0 8452.0
MAP2K6 9435.0 9577.0
MAPK1 1052.0 9260.0
MAPK11 7257.0 1843.0
MAPK12 1925.0 -1837.0
MAPK13 -8511.0 5595.0
MAPK14 9907.0 9606.0
MAPK3 8931.0 9626.0
MAPK7 -10125.0 5069.0
MAPK8 -1061.0 -9914.0
MBP -9968.0 959.0
MED1 -2730.0 -1762.0
MED10 -5268.0 -7090.0
MED11 -5849.0 3435.0
MED12 -6426.0 4924.0
MED13 3230.0 3171.0
MED13L 5428.0 7259.0
MED14 -1391.0 1994.0
MED15 -9816.0 -5112.0
MED16 1626.0 7040.0
MED17 6659.0 2906.0
MED18 -3248.0 7029.0
MED19 4205.0 3722.0
MED20 4514.0 8084.0
MED21 2129.0 -7223.0
MED22 -1721.0 5575.0
MED23 -4613.0 -4897.0
MED24 -9186.0 -918.0
MED25 4853.0 7553.0
MED26 -5273.0 7174.0
MED27 -10124.0 -2305.0
MED28 2447.0 -1143.0
MED29 -9108.0 -967.0
MED30 -7460.0 -966.0
MED31 7152.0 -877.0
MED4 5576.0 3120.0
MED6 5195.0 -1751.0
MED7 1493.0 1153.0
MED8 7164.0 8014.0
MED9 -9724.0 -1868.0
MEF2A 9000.0 8162.0
MEF2B 7261.0 6219.0
MEF2C 6943.0 -2868.0
MEF2D -9268.0 3542.0
MEIS1 -6626.0 808.0
MMP9 9225.0 9700.0
MPZ 5213.0 8837.0
MSN -4366.0 7815.0
MYB 6506.0 -1852.0
MYC 8429.0 -2186.0
MYH10 -7101.0 3044.0
MYH11 1903.0 -4778.0
MYH9 1879.0 8348.0
MYL12A 5517.0 7412.0
MYL12B -2612.0 6816.0
MYL6 6786.0 9643.0
MYL9 9640.0 7741.0
MYO10 9409.0 9473.0
MYO9B 513.0 8592.0
NAB1 7194.0 -445.0
NAB2 -9246.0 -7768.0
NANOG 5462.0 317.0
NCAM1 -11155.0 -5990.0
NCBP1 1766.0 -6055.0
NCBP2 3719.0 -10143.0
NCK1 -9250.0 -9113.0
NCK2 4176.0 5976.0
NCOA1 -1753.0 6268.0
NCOA2 -4443.0 3788.0
NCOA3 3630.0 4256.0
NCOA6 1381.0 7728.0
NCOR1 3309.0 7790.0
NCOR2 4843.0 9646.0
NCSTN 9503.0 9869.0
NELL2 -5567.0 -11253.0
NEO1 -10312.0 -6091.0
NFKB1 7857.0 6377.0
NODAL -6175.0 -2893.0
NOTCH1 -6446.0 6708.0
NR6A1 8944.0 8922.0
NRAS 7321.0 4878.0
NRCAM 3909.0 -4264.0
NRP1 -9711.0 -5356.0
NRP2 -1597.0 -4081.0
NTN1 -6523.0 -1814.0
NTN3 -2517.0 1886.0
NTN4 -8477.0 -6391.0
NUMB 10040.0 10006.0
ONECUT1 1868.0 3240.0
ONECUT3 5096.0 -6028.0
PABPC1 8362.0 4524.0
PAGR1 357.0 7005.0
PAK1 9711.0 7682.0
PAK2 9019.0 8433.0
PAK3 -1134.0 -4249.0
PAK4 -5379.0 2021.0
PAK6 -11089.0 -6507.0
PAXIP1 188.0 -8959.0
PBX1 1959.0 6243.0
PCGF2 -3955.0 -2094.0
PCSK6 9717.0 9061.0
PDLIM7 9040.0 9528.0
PERP -6680.0 -9891.0
PFN1 -5663.0 7801.0
PFN2 5971.0 -5360.0
PI3 8550.0 -782.0
PIAS2 -2649.0 -6975.0
PIK3CA 6889.0 4182.0
PIK3CB 9838.0 9248.0
PIK3CD 82.0 7288.0
PIK3R1 -7197.0 -8942.0
PIK3R2 2459.0 5820.0
PIK3R3 -11107.0 -8159.0
PIP5K1C -4447.0 6435.0
PITPNA 6122.0 7384.0
PKNOX1 -9178.0 1412.0
PKP2 5219.0 6139.0
PKP4 5362.0 2981.0
PLCG1 -6360.0 -11043.0
PLIN1 -6629.0 -678.0
PLXNA1 -4542.0 -7632.0
PLXNA2 6094.0 8143.0
PLXNA3 -808.0 -9446.0
PLXNA4 -10098.0 -9511.0
PLXNB1 4183.0 6269.0
PLXNB3 9445.0 9527.0
PLXNC1 9678.0 9690.0
PLXND1 6191.0 8701.0
PML -6449.0 -6720.0
PMP22 -8796.0 -1405.0
POLR2A -8726.0 2901.0
POLR2B -1034.0 188.0
POLR2C -2183.0 3527.0
POLR2D 3401.0 -4083.0
POLR2E 6766.0 8343.0
POLR2F -2307.0 6746.0
POLR2G -5778.0 6576.0
POLR2H 653.0 -2264.0
POLR2I -2123.0 2695.0
POLR2J 4448.0 7822.0
POLR2K 1881.0 -1885.0
POLR2L 126.0 7246.0
POU5F1 -3823.0 3078.0
PPARA -791.0 2682.0
PPARG 10111.0 10137.0
PPARGC1A 7923.0 1692.0
PPL -5435.0 3144.0
PPP3CB 8057.0 6833.0
PRKACA 9885.0 10068.0
PRKACB -9852.0 -10936.0
PRKAR2A 3755.0 7093.0
PRKCA 2473.0 1229.0
PRKCQ -10709.0 -10890.0
PRNP 6403.0 3832.0
PRSS8 -2258.0 1231.0
PRX -7273.0 -846.0
PSEN1 7889.0 8878.0
PSEN2 -5169.0 -5867.0
PSENEN 2692.0 7551.0
PSMA1 8278.0 7406.0
PSMA2 5830.0 5666.0
PSMA3 4646.0 -7621.0
PSMA4 3950.0 -1036.0
PSMA5 -2119.0 -3983.0
PSMA6 6893.0 5865.0
PSMA7 3550.0 8554.0
PSMB1 3915.0 4224.0
PSMB10 -7878.0 -1272.0
PSMB2 2664.0 4928.0
PSMB3 4971.0 8382.0
PSMB4 -3175.0 4911.0
PSMB5 6561.0 9138.0
PSMB6 1312.0 8784.0
PSMB7 8034.0 9051.0
PSMB8 -4481.0 75.0
PSMB9 -9105.0 -10433.0
PSMC1 6759.0 7782.0
PSMC2 -2524.0 4517.0
PSMC3 -4971.0 4984.0
PSMC4 -10757.0 -336.0
PSMC5 -3424.0 2764.0
PSMC6 8812.0 6000.0
PSMD1 7679.0 7587.0
PSMD10 2067.0 2450.0
PSMD11 6914.0 6824.0
PSMD12 9011.0 5710.0
PSMD13 3157.0 7205.0
PSMD14 2891.0 3041.0
PSMD2 4352.0 8396.0
PSMD3 -2243.0 6367.0
PSMD4 6858.0 9449.0
PSMD5 2770.0 4781.0
PSMD6 8841.0 8304.0
PSMD7 6534.0 6147.0
PSMD8 739.0 7117.0
PSMD9 3580.0 9001.0
PSME1 -7256.0 -7913.0
PSME2 -5548.0 -10355.0
PSME3 9120.0 8239.0
PSME4 -5205.0 -3127.0
PSMF1 6709.0 6770.0
PSPN 6438.0 2245.0
PTK2 7786.0 3481.0
PTPN11 4691.0 6614.0
PTPRA -10794.0 3851.0
PTPRC -3326.0 4087.0
RAC1 9052.0 9614.0
RANBP9 3568.0 6133.0
RAP1GAP 10118.0 7895.0
RARA -356.0 8119.0
RARG -1415.0 -3798.0
RASA1 4308.0 2428.0
RBBP4 4016.0 -1020.0
RBBP5 4931.0 173.0
RBBP7 -10846.0 -9848.0
RBM8A -8943.0 -463.0
RBPJ 9652.0 9125.0
RBX1 1418.0 4877.0
RDX 8947.0 8952.0
RELA -7305.0 2739.0
RELN -9664.0 4875.0
RET -10107.0 -2874.0
RGMA 8099.0 7880.0
RGMB 4862.0 -8328.0
RHOA 8351.0 8888.0
RHOB -4807.0 3859.0
RHOC -11158.0 -4627.0
RND1 -1747.0 -757.0
RNPS1 -9956.0 -5868.0
ROBO1 -43.0 212.0
ROBO3 -9341.0 -9311.0
ROCK1 8315.0 7930.0
ROCK2 7628.0 6719.0
RPL10 -5353.0 -4722.0
RPL10A -1883.0 -6533.0
RPL11 -1931.0 -5590.0
RPL12 -4453.0 -5830.0
RPL13 -1749.0 -2925.0
RPL13A -5236.0 -7060.0
RPL14 -3538.0 -6408.0
RPL15 2144.0 -270.0
RPL17 -2803.0 -4216.0
RPL18 -2407.0 -4107.0
RPL18A -4338.0 -4740.0
RPL19 -5605.0 -4047.0
RPL21 -2408.0 -6412.0
RPL22 1616.0 -5576.0
RPL22L1 3994.0 -3396.0
RPL23 -353.0 -2321.0
RPL23A -4695.0 -9373.0
RPL24 -3568.0 -4504.0
RPL26 -4494.0 -4767.0
RPL26L1 6548.0 7865.0
RPL27 -3684.0 -361.0
RPL27A -5814.0 -4093.0
RPL28 -2567.0 614.0
RPL29 -2138.0 -1913.0
RPL3 -6886.0 -7461.0
RPL30 -5225.0 -5596.0
RPL31 -2656.0 -3267.0
RPL32 -3094.0 -6607.0
RPL34 -2097.0 -7114.0
RPL35 -8453.0 -5007.0
RPL35A -2671.0 -5323.0
RPL36 -6761.0 -2662.0
RPL36A -5740.0 -5975.0
RPL36AL -1773.0 1920.0
RPL37 -8529.0 -2184.0
RPL37A -5802.0 -727.0
RPL38 -7075.0 -2793.0
RPL39 -983.0 -3231.0
RPL39L -10310.0 -4203.0
RPL4 2174.0 -3722.0
RPL41 -7404.0 -3692.0
RPL5 2979.0 -5487.0
RPL6 3510.0 -3949.0
RPL7 3811.0 -2799.0
RPL7A -2851.0 -1500.0
RPL8 -4534.0 1780.0
RPL9 -167.0 -2256.0
RPLP0 3127.0 -1531.0
RPLP1 -2483.0 2491.0
RPLP2 -7230.0 -4974.0
RPS10 -5228.0 -3784.0
RPS11 -7652.0 -3921.0
RPS12 -4698.0 -5458.0
RPS13 3315.0 -2060.0
RPS14 -6862.0 -2786.0
RPS15 -4712.0 -988.0
RPS15A -3464.0 -4486.0
RPS16 -3811.0 -3249.0
RPS17 -6899.0 -3309.0
RPS18 -6859.0 -6415.0
RPS19 -5797.0 -5539.0
RPS2 -6072.0 -1316.0
RPS20 -6536.0 -7674.0
RPS21 -4436.0 -2455.0
RPS23 -1921.0 -5872.0
RPS24 3926.0 -838.0
RPS25 -1359.0 -6741.0
RPS26 -1177.0 -1112.0
RPS27 -9041.0 -7909.0
RPS27A -3555.0 -7070.0
RPS27L 5307.0 1458.0
RPS28 -5391.0 -2679.0
RPS29 -8497.0 -5396.0
RPS3 -4098.0 -4595.0
RPS3A 3428.0 -6271.0
RPS4X -1869.0 -6447.0
RPS4Y1 5773.0 -56.0
RPS5 -4290.0 -4473.0
RPS6 -1613.0 -5951.0
RPS6KA1 -105.0 9153.0
RPS6KA2 -5428.0 3882.0
RPS6KA3 2859.0 3437.0
RPS6KA4 37.0 3324.0
RPS6KA5 -3980.0 -11177.0
RPS6KA6 -4679.0 -4228.0
RPS7 -1789.0 -4131.0
RPS8 2338.0 -2478.0
RPS9 3357.0 6145.0
RPSA -2286.0 -5572.0
RRAS -5315.0 5342.0
RUNX1 7796.0 7867.0
RXRA 6327.0 8932.0
SALL4 -8382.0 -2248.0
SCD5 -10066.0 -2380.0
SCN1B 1896.0 7235.0
SCN2A 4998.0 2549.0
SCN2B 2511.0 845.0
SCN3A -1644.0 -1779.0
SCN3B -5343.0 -6093.0
SCN4A -3952.0 -5258.0
SCN5A -453.0 5075.0
SCN7A -4945.0 -5474.0
SCN8A -5545.0 -2922.0
SCN9A -5909.0 1891.0
SDC2 7232.0 4710.0
SDCBP 9944.0 9687.0
SEM1 993.0 5942.0
SEMA3A -3998.0 -5644.0
SEMA4A 9573.0 9599.0
SEMA4D -2346.0 -627.0
SEMA5A -7754.0 -9477.0
SEMA6A -6066.0 -6800.0
SEMA7A -9585.0 -5587.0
SH3KBP1 4345.0 7311.0
SHANK3 -8348.0 -6498.0
SHC1 -3416.0 5815.0
SHC3 9229.0 -1001.0
SHTN1 9752.0 7050.0
SIAH1 -5833.0 454.0
SIAH2 9783.0 8092.0
SLIT1 -816.0 7188.0
SLIT3 -4033.0 2188.0
SMAD2 5238.0 5871.0
SMAD3 -10084.0 -10081.0
SMAD4 -3009.0 -6696.0
SMARCA4 -2731.0 7803.0
SMARCD3 9870.0 8230.0
SNW1 6824.0 5161.0
SOS1 3534.0 -7412.0
SOS2 9141.0 8628.0
SOX10 -3857.0 -5196.0
SPAG9 4251.0 6027.0
SPI1 8925.0 9551.0
SPTA1 9470.0 6216.0
SPTAN1 -10174.0 -8889.0
SPTB 9958.0 9302.0
SPTBN1 -6572.0 -6164.0
SPTBN2 -5447.0 -3871.0
SPTBN5 -7557.0 -461.0
SRC -6857.0 -7229.0
SREBF1 8758.0 5979.0
SREBF2 5424.0 7541.0
SRGAP1 6525.0 7219.0
SRGAP2 4493.0 7351.0
SRGAP3 -4761.0 -4198.0
ST14 10019.0 9752.0
ST8SIA4 9016.0 8665.0
STAT3 8512.0 8606.0
STX1A -9454.0 1322.0
STX1B 2007.0 -4381.0
SUZ12 4539.0 -3535.0
TAL1 7521.0 6960.0
TBL1X 8359.0 8499.0
TBL1XR1 4714.0 4779.0
TCF12 -1570.0 891.0
TCF3 -6954.0 -4308.0
TCF4 -6491.0 -2021.0
TFDP1 9824.0 8225.0
TFDP2 -11249.0 -10144.0
TGFB1 -2566.0 6745.0
TGM1 -573.0 -6264.0
TGS1 -141.0 -4762.0
THRAP3 -3609.0 3263.0
TIAM1 5732.0 -809.0
TLN1 7865.0 9661.0
TNF -3598.0 -6316.0
TRIO -2029.0 3636.0
TRPC1 -2448.0 -10832.0
TRPC3 -9747.0 -5879.0
TRPC6 -4419.0 130.0
TSC22D1 4346.0 5116.0
TYROBP 6139.0 8494.0
UBA52 -1875.0 3023.0
UBB 8251.0 6157.0
UBC -1915.0 5825.0
UNC5A 7830.0 9203.0
UNC5B 1281.0 3970.0
UPF2 2672.0 1146.0
UPF3A -7689.0 -8218.0
UPF3B -6089.0 -6826.0
USP33 5005.0 -1397.0
UTRN -10596.0 -9572.0
VASP 7010.0 8703.0
VAV2 -5033.0 -1339.0
VAV3 -6160.0 7203.0
VLDLR -9564.0 1877.0
WASL 899.0 1391.0
WDR5 671.0 2111.0
WNT1 -7238.0 -8407.0
WNT10B -9917.0 -7977.0
WWTR1 -6909.0 -4483.0
YES1 -11138.0 -8566.0
YY1 -627.0 3060.0
ZNF335 -8981.0 -3118.0
ZNF467 9518.0 9772.0
ZNF638 7938.0 2667.0
ZSWIM8 -5707.0 8065.0



Interleukin-1 family signaling

Interleukin-1 family signaling
metric value
setSize 124
pMANOVA 4.75e-13
p.adjustMANOVA 1.54e-11
s.dist 0.459
s.low.CRP 0.24
s.high.CRP 0.391
p.low.CRP 4.08e-06
p.high.CRP 4.94e-14




Top 20 genes
Gene low CRP high CRP
S100A12 10088 10121
IL1RN 10087 9470
NKIRAS2 9581 9936
APP 9951 9504
IRAK3 9660 9553
MAP2K1 9163 9879
ALOX5 9516 9496
MAP2K6 9435 9577
IL1R1 9455 9194
PELI2 9242 9060
NOD2 9408 8613
TOLLIP 8447 9165
MAP3K3 8280 9287
PSME3 9120 8239
PTPN12 7921 9275
PSMD6 8841 8304
STAT3 8512 8606
PSMB7 8034 9051
MYD88 8651 8344
CHUK 9198 7663

Click HERE to show all gene set members

All member genes
low CRP high CRP
AGER -1839 3181
ALOX5 9516 9496
APP 9951 9504
BTRC -6845 -441
CASP1 8236 2513
CHUK 9198 7663
CTSG 9156 1689
CUL1 -2085 -10951
FBXW11 4585 7364
HMGB1 3876 -968
IKBKB -5276 -2118
IKBKG -3058 7903
IL18 8340 7387
IL18BP -8737 -8962
IL18R1 -10880 5790
IL18RAP -11230 5060
IL1B 7489 3385
IL1R1 9455 9194
IL1R2 6574 9865
IL1RAP 3294 7375
IL1RL1 8858 -1567
IL1RN 10087 9470
IL33 -438 931
IL4 -7559 -9214
IRAK1 2444 7601
IRAK2 -11058 -2404
IRAK3 9660 9553
MAP2K1 9163 9879
MAP2K4 6895 7431
MAP2K6 9435 9577
MAP3K3 8280 9287
MAP3K7 1546 4274
MAP3K8 -7139 8928
MAPK8 -1061 -9914
MYD88 8651 8344
NFKB1 7857 6377
NFKB2 3069 -1167
NFKBIA 6855 7374
NFKBIB -9679 5479
NKIRAS1 2619 689
NKIRAS2 9581 9936
NOD1 -10930 -10348
NOD2 9408 8613
PELI1 9064 5690
PELI2 9242 9060
PELI3 5708 8764
PSMA1 8278 7406
PSMA2 5830 5666
PSMA3 4646 -7621
PSMA4 3950 -1036
PSMA5 -2119 -3983
PSMA6 6893 5865
PSMA7 3550 8554
PSMB1 3915 4224
PSMB10 -7878 -1272
PSMB2 2664 4928
PSMB3 4971 8382
PSMB4 -3175 4911
PSMB5 6561 9138
PSMB6 1312 8784
PSMB7 8034 9051
PSMB8 -4481 75
PSMB9 -9105 -10433
PSMC1 6759 7782
PSMC2 -2524 4517
PSMC3 -4971 4984
PSMC4 -10757 -336
PSMC5 -3424 2764
PSMC6 8812 6000
PSMD1 7679 7587
PSMD10 2067 2450
PSMD11 6914 6824
PSMD12 9011 5710
PSMD13 3157 7205
PSMD14 2891 3041
PSMD2 4352 8396
PSMD3 -2243 6367
PSMD4 6858 9449
PSMD5 2770 4781
PSMD6 8841 8304
PSMD7 6534 6147
PSMD8 739 7117
PSMD9 3580 9001
PSME1 -7256 -7913
PSME2 -5548 -10355
PSME3 9120 8239
PSME4 -5205 -3127
PSMF1 6709 6770
PTPN11 4691 6614
PTPN12 7921 9275
PTPN13 -9422 -7282
PTPN14 444 -2588
PTPN18 -1694 8540
PTPN2 7776 8909
PTPN20 2731 -4226
PTPN23 -4984 2588
PTPN4 -10946 -10632
PTPN6 -691 7862
PTPN7 -10607 -6009
PTPN9 -2214 8622
RBX1 1418 4877
RELA -7305 2739
RIPK2 1665 2297
RPS27A -3555 -7070
S100A12 10088 10121
S100B -8212 -1271
SEM1 993 5942
SIGIRR -9900 -8613
SKP1 8120 2700
SMAD3 -10084 -10081
SQSTM1 4693 4549
STAT3 8512 8606
TAB1 6623 5746
TAB2 9197 5726
TAB3 3912 3647
TBK1 5846 2973
TNIP2 -1490 7359
TOLLIP 8447 9165
TRAF6 -1767 2089
UBA52 -1875 3023
UBB 8251 6157
UBC -1915 5825
UBE2N 4087 2050
UBE2V1 6665 5995



Antigen processing-Cross presentation

Antigen processing-Cross presentation
metric value
setSize 97
pMANOVA 7.58e-13
p.adjustMANOVA 2.4e-11
s.dist 0.509
s.low.CRP 0.258
s.high.CRP 0.438
p.low.CRP 1.08e-05
p.high.CRP 8.2e-14




Top 20 genes
Gene low CRP high CRP
CD36 10064 9814
NCF4 9697 9856
FCGR1A 9965 9575
NCF2 9748 9694
CD14 9551 9658
TLR4 9494 9617
TLR2 9930 9118
FCGR1B 9834 9178
TLR6 9634 9209
CYBB 9900 8910
TLR1 9828 8868
LY96 9529 8995
SNAP23 9586 8642
VAMP3 9204 8284
PSME3 9120 8239
PSMD6 8841 8304
PSMB7 8034 9051
MYD88 8651 8344
CTSS 9854 7280
CHUK 9198 7663

Click HERE to show all gene set members

All member genes
low CRP high CRP
B2M -4257 -4660
BTK 7623 7870
CALR 6685 6374
CD14 9551 9658
CD36 10064 9814
CHUK 9198 7663
CTSL -5538 5895
CTSS 9854 7280
CTSV -1271 -2930
CYBA -48 8901
CYBB 9900 8910
FCGR1A 9965 9575
FCGR1B 9834 9178
HLA-A -5067 570
HLA-B -1559 1570
HLA-C -2829 2125
HLA-E -10409 2003
HLA-F -10598 -7440
HLA-G -5051 159
HLA-H -8161 452
IKBKB -5276 -2118
IKBKG -3058 7903
ITGAV 7467 6188
ITGB5 7729 7327
LNPEP -8634 -6784
LY96 9529 8995
MRC1 -6259 4719
MRC2 4574 -2049
MYD88 8651 8344
NCF1 8576 7083
NCF2 9748 9694
NCF4 9697 9856
PDIA3 2037 4838
PSMA1 8278 7406
PSMA2 5830 5666
PSMA3 4646 -7621
PSMA4 3950 -1036
PSMA5 -2119 -3983
PSMA6 6893 5865
PSMA7 3550 8554
PSMB1 3915 4224
PSMB10 -7878 -1272
PSMB2 2664 4928
PSMB3 4971 8382
PSMB4 -3175 4911
PSMB5 6561 9138
PSMB6 1312 8784
PSMB7 8034 9051
PSMB8 -4481 75
PSMB9 -9105 -10433
PSMC1 6759 7782
PSMC2 -2524 4517
PSMC3 -4971 4984
PSMC4 -10757 -336
PSMC5 -3424 2764
PSMC6 8812 6000
PSMD1 7679 7587
PSMD10 2067 2450
PSMD11 6914 6824
PSMD12 9011 5710
PSMD13 3157 7205
PSMD14 2891 3041
PSMD2 4352 8396
PSMD3 -2243 6367
PSMD4 6858 9449
PSMD5 2770 4781
PSMD6 8841 8304
PSMD7 6534 6147
PSMD8 739 7117
PSMD9 3580 9001
PSME1 -7256 -7913
PSME2 -5548 -10355
PSME3 9120 8239
PSME4 -5205 -3127
PSMF1 6709 6770
RPS27A -3555 -7070
SEC22B 8663 4943
SEC61A1 5496 7020
SEC61A2 -8826 -9671
SEC61B 4953 8362
SEC61G 7533 3614
SEM1 993 5942
SNAP23 9586 8642
STX4 -7285 5736
TAP1 -8207 -9297
TAP2 -9895 -10077
TAPBP -5450 4788
TIRAP 262 7730
TLR1 9828 8868
TLR2 9930 9118
TLR4 9494 9617
TLR6 9634 9209
UBA52 -1875 3023
UBB 8251 6157
UBC -1915 5825
VAMP3 9204 8284
VAMP8 2890 6767



RHO GTPase Effectors

RHO GTPase Effectors
metric value
setSize 248
pMANOVA 1.12e-12
p.adjustMANOVA 3.47e-11
s.dist 0.319
s.low.CRP 0.165
s.high.CRP 0.273
p.low.CRP 7.43e-06
p.high.CRP 1.19e-13




Top 20 genes
Gene low CRP high CRP
S100A9 10110 10116
WASF1 10091 10132
S100A8 10041 10093
YWHAG 9658 9994
CTNNA1 9646 10004
CYFIP1 9724 9912
GRB2 9631 9985
NCF4 9697 9856
MAPK14 9907 9606
H2BC21 9852 9656
NCF2 9748 9694
YWHAE 9721 9563
ARPC1B 9259 10026
H2AJ 8999 10117
PRKCD 9393 9642
ACTB 9310 9714
H2BC12 9066 9812
CYBB 9900 8910
DLG4 9905 8876
YWHAH 9519 9189

Click HERE to show all gene set members

All member genes
low CRP high CRP
ABI1 6692.0 7709.0
ABI2 -7512.0 -9823.0
ABL1 -6354.0 4467.0
ACTB 9310.0 9714.0
ACTG1 7674.0 9499.0
ACTR2 8743.0 7962.0
ACTR3 8622.0 7832.0
AHCTF1 -1588.0 -103.0
AR 5214.0 4808.0
ARPC1A 8875.0 9605.0
ARPC1B 9259.0 10026.0
ARPC2 5327.0 8212.0
ARPC3 8430.0 8946.0
ARPC4 4637.0 8915.0
ARPC5 9301.0 9174.0
AURKB -4097.0 3408.0
B9D2 8167.0 8798.0
BAIAP2 2620.0 -682.0
BIRC5 2725.0 4169.0
BRK1 5522.0 8298.0
BTK 7623.0 7870.0
BUB1 5839.0 1925.0
BUB1B 3929.0 2104.0
BUB3 -7777.0 -10711.0
CALM1 -6645.0 1321.0
CDC20 -74.0 5136.0
CDC42 8498.0 7640.0
CDCA8 -4836.0 412.0
CDH1 -10697.0 -8067.0
CDKN1B -9926.0 -2672.0
CENPA 3195.0 4228.0
CENPC -8807.0 -11097.0
CENPE -3467.0 886.0
CENPF -1889.0 3258.0
CENPH -3269.0 -8735.0
CENPI -2474.0 -2641.0
CENPK -2160.0 -9816.0
CENPL -10630.0 -8812.0
CENPM 1385.0 -7204.0
CENPN 4436.0 -1101.0
CENPO -10840.0 3129.0
CENPP -10848.0 -8710.0
CENPQ -911.0 -6285.0
CENPT -7579.0 -8354.0
CENPU -4192.0 -6597.0
CFL1 5851.0 9242.0
CIT -7580.0 -2898.0
CKAP5 -6411.0 -2392.0
CLASP1 -9685.0 4156.0
CLASP2 2388.0 -1797.0
CLIP1 9515.0 8973.0
CTNNA1 9646.0 10004.0
CTNNB1 3201.0 7613.0
CTTN 7016.0 6516.0
CYBA -48.0 8901.0
CYBB 9900.0 8910.0
CYFIP1 9724.0 9912.0
CYFIP2 -10558.0 -4935.0
DAAM1 4929.0 3983.0
DIAPH1 -9216.0 4270.0
DIAPH2 9067.0 9290.0
DIAPH3 6644.0 3344.0
DLG4 9905.0 8876.0
DSN1 -8825.0 -8996.0
DVL1 -1093.0 1894.0
DVL2 -10305.0 -7147.0
DVL3 -4437.0 8389.0
DYNC1H1 -8881.0 -2533.0
DYNC1I1 7141.0 2722.0
DYNC1I2 8160.0 8196.0
DYNC1LI1 7894.0 6997.0
DYNC1LI2 3494.0 5636.0
DYNLL1 6026.0 6499.0
DYNLL2 -6325.0 -225.0
ERCC6L 2328.0 -1028.0
EVL -10613.0 -11193.0
FLNA -8145.0 4196.0
FMNL1 -7128.0 6527.0
FMNL2 -9177.0 -556.0
FMNL3 -11025.0 -9852.0
GOPC -3131.0 -9251.0
GRB2 9631.0 9985.0
H2AC20 -790.0 6112.0
H2AC6 8700.0 8169.0
H2AJ 8999.0 10117.0
H2AZ1 1779.0 7321.0
H2AZ2 -4042.0 2210.0
H2BC11 8424.0 8288.0
H2BC12 9066.0 9812.0
H2BC15 3036.0 6455.0
H2BC17 7882.0 7312.0
H2BC21 9852.0 9656.0
H2BC4 7156.0 7805.0
H2BC5 7596.0 8773.0
H2BC9 7965.0 4715.0
H2BU1 -6349.0 -3895.0
H3-3A 9297.0 9034.0
H3C15 5262.5 7402.5
INCENP -9437.0 323.0
IQGAP1 7310.0 9366.0
IQGAP2 6198.0 7948.0
IQGAP3 3938.0 3957.0
ITGB1 3360.0 -108.0
ITGB3BP -458.0 -8029.0
KDM1A -6245.0 -6064.0
KDM4C -9638.0 -6288.0
KIF14 1714.0 3512.0
KIF18A -5118.0 -1862.0
KIF2A 2515.0 -1329.0
KIF2C 2032.0 104.0
KIF5A -7037.0 -7903.0
KIF5B 9540.0 8103.0
KLC1 1745.0 7386.0
KLC2 -6674.0 -7322.0
KLC3 8390.0 7398.0
KLC4 -9223.0 -3527.0
KLK2 7104.0 1104.0
KNL1 -1431.0 -91.0
KNTC1 -224.0 -8592.0
KTN1 7536.0 1922.0
LIMK1 -2747.0 6617.0
LIMK2 8349.0 8299.0
LIN7B -5596.0 -560.0
MAD1L1 -7936.0 -748.0
MAD2L1 -1797.0 -8340.0
MAPK1 1052.0 9260.0
MAPK11 7257.0 1843.0
MAPK14 9907.0 9606.0
MAPK3 8931.0 9626.0
MAPRE1 8382.0 7653.0
MEN1 -8589.0 -4575.0
MIS12 -6139.0 -10061.0
MRTFA 7793.0 9266.0
MYH10 -7101.0 3044.0
MYH11 1903.0 -4778.0
MYH9 1879.0 8348.0
MYL12B -2612.0 6816.0
MYL6 6786.0 9643.0
MYL9 9640.0 7741.0
MYLK 8091.0 6661.0
NCF1 8576.0 7083.0
NCF2 9748.0 9694.0
NCF4 9697.0 9856.0
NCK1 -9250.0 -9113.0
NCKAP1 6871.0 8168.0
NCKAP1L 3966.0 9566.0
NCKIPSD 957.0 1858.0
NCOA2 -4443.0 3788.0
NDC80 -4016.0 -9035.0
NDE1 2098.0 4048.0
NDEL1 5664.0 8515.0
NF2 -9157.0 -819.0
NOXA1 -2600.0 -5589.0
NSL1 6939.0 5555.0
NUDC -2705.0 2609.0
NUF2 -4390.0 -3313.0
NUP107 -4463.0 -10317.0
NUP133 -4339.0 -4616.0
NUP160 -2518.0 -10020.0
NUP37 3188.0 3613.0
NUP43 -55.0 -10161.0
NUP85 1119.0 -2732.0
NUP98 208.0 4310.0
PAFAH1B1 -336.0 6894.0
PAK1 9711.0 7682.0
PAK2 9019.0 8433.0
PAK3 -1134.0 -4249.0
PDPK1 2392.0 7816.0
PFN1 -5663.0 7801.0
PFN2 5971.0 -5360.0
PIK3C3 6605.0 573.0
PIK3R4 -267.0 -2209.0
PIN1 -9660.0 3728.0
PKN1 -10294.0 5192.0
PKN2 6764.0 -3104.0
PKN3 -6719.0 -1067.0
PLK1 -235.0 4265.0
PMF1 3040.0 4375.0
PPP1CB 8657.0 6666.0
PPP1CC 9200.0 4868.0
PPP1R12A 5601.0 6368.0
PPP1R12B -4326.0 4036.0
PPP1R14A 7499.0 7460.0
PPP2CA 8810.0 8328.0
PPP2CB 8482.0 7631.0
PPP2R1A -3087.0 6994.0
PPP2R1B 2503.0 437.0
PPP2R5A -903.0 6957.0
PPP2R5B 5288.0 7952.0
PPP2R5C -10420.0 -7112.0
PPP2R5D -6508.0 4985.0
PPP2R5E 715.0 540.0
PRC1 -5431.0 2601.0
PRKCA 2473.0 1229.0
PRKCB 5395.0 8378.0
PRKCD 9393.0 9642.0
PRKCZ -10855.0 -7708.0
PTK2 7786.0 3481.0
RAC1 9052.0 9614.0
RAC2 -7677.0 6828.0
RANBP2 4453.0 -2222.0
RANGAP1 -10259.0 -9220.0
RCC2 -6741.0 -781.0
RHOA 8351.0 8888.0
RHOB -4807.0 3859.0
RHOC -11158.0 -4627.0
RHOG 7549.0 9255.0
RHOQ 9504.0 6692.0
RHPN1 2265.0 -8079.0
RHPN2 -2702.0 -4003.0
ROCK1 8315.0 7930.0
ROCK2 7628.0 6719.0
RPS27 -9041.0 -7909.0
RTKN -11144.0 -10917.0
S100A8 10041.0 10093.0
S100A9 10110.0 10116.0
SCAI -420.0 -7606.0
SEC13 2125.0 6861.0
SEH1L 7189.0 -8511.0
SFN -918.0 1127.0
SGO1 -7321.0 -4581.0
SGO2 285.0 -3804.0
SKA1 4635.0 1882.0
SKA2 -7953.0 -5579.0
SPC24 -1637.0 3696.0
SPDL1 -8869.0 -10380.0
SRC -6857.0 -7229.0
SRF 4035.0 7760.0
SRGAP2 4493.0 7351.0
TAOK1 5604.0 6063.0
TAX1BP3 8203.0 8751.0
WAS 8258.0 9323.0
WASF1 10091.0 10132.0
WASF2 7535.0 9576.0
WASF3 8142.0 7240.0
WASL 899.0 1391.0
WIPF1 -5700.0 3866.0
WIPF2 2722.0 7125.0
XPO1 6563.0 -3235.0
YWHAB 8274.0 6101.0
YWHAE 9721.0 9563.0
YWHAG 9658.0 9994.0
YWHAH 9519.0 9189.0
YWHAQ -9021.0 -1643.0
YWHAZ 5165.0 5861.0
ZW10 5778.0 -752.0
ZWILCH -9080.0 -10492.0
ZWINT -1751.0 -5219.0



Regulation of Complement cascade

Regulation of Complement cascade
metric value
setSize 93
pMANOVA 1.56e-12
p.adjustMANOVA 4.61e-11
s.dist 0.274
s.low.CRP 0.203
s.high.CRP -0.185
p.low.CRP 0.00071
p.high.CRP 0.00209




Top 20 genes
Gene low CRP high CRP
IGKV3-11 5548 -7167
IGKV1-33 5955 -6384
IGKV1-16 6217 -5451
IGKV1-5 6127 -5162
IGLV5-45 4194 -7364
IGHV3-23 6032 -5092
IGKV2-30 5205 -5349
IGLV1-44 4742 -5791
IGHV4-59 4532 -5870
IGLV2-8 4818 -5256
IGHV4-39 3786 -6542
IGLV3-19 4006 -5611
IGHV1-2 5956 -3146
IGKV3-20 3704 -5021
IGKC 2773 -6437
IGLV1-36 3522 -5030
C4BPB 3624 -4862
IGHV3-11 3518 -4591
IGHV3-7 4185 -3630
IGKV3-15 3174 -4687

Click HERE to show all gene set members

All member genes
low CRP high CRP
C1QA -49 7890
C1QB 6746 8930
C1QC 7805 9340
C1R -10393 -4020
C1S -6159 552
C2 6634 2959
C3 -11179 -10489
C3AR1 8924 8181
C4A 5060 4740
C4B 6359 2884
C4BPB 3624 -4862
C5 7727 2354
C5AR1 9359 9709
C5AR2 8198 8666
C8G -10839 -8035
CD19 -2992 -2929
CD46 8744 5145
CD55 9326 9842
CD59 4075 5772
CD81 -10685 -3573
CFB -3014 -2968
CFH -3147 -6338
CLU 9512 10102
CPN2 8266 1159
CR1 10079 10078
CR2 -1342 -3900
ELANE 9880 4888
IGHG1 -1124 -7111
IGHG2 -5587 -6004
IGHG3 -507 -4089
IGHG4 -4038 -5940
IGHV1-2 5956 -3146
IGHV1-46 3766 -2976
IGHV1-69 2354 -2328
IGHV2-5 4451 -1972
IGHV2-70 -3315 -2159
IGHV3-11 3518 -4591
IGHV3-13 799 -2451
IGHV3-23 6032 -5092
IGHV3-30 2500 -5193
IGHV3-33 98 -4138
IGHV3-48 3183 -4340
IGHV3-53 3131 -1786
IGHV3-7 4185 -3630
IGHV4-34 1144 -4007
IGHV4-39 3786 -6542
IGHV4-59 4532 -5870
IGKC 2773 -6437
IGKV1-12 725 -6674
IGKV1-16 6217 -5451
IGKV1-17 -241 -2794
IGKV1-33 5955 -6384
IGKV1-5 6127 -5162
IGKV1D-39 5018 -2677
IGKV2-28 1440 -6662
IGKV2-30 5205 -5349
IGKV2D-28 -7224 -2947
IGKV3-11 5548 -7167
IGKV3-15 3174 -4687
IGKV3-20 3704 -5021
IGKV3D-20 -1830 -4618
IGKV4-1 2812 -4988
IGKV5-2 5226 -2682
IGLC1 -2813 -6176
IGLC2 -258 -6539
IGLC3 -2958 -4378
IGLC7 -3403 -4490
IGLV1-36 3522 -5030
IGLV1-40 163 -5497
IGLV1-44 4742 -5791
IGLV1-47 231 -6633
IGLV1-51 1708 -6601
IGLV10-54 -5422 316
IGLV2-11 870 -3205
IGLV2-14 -5127 -8197
IGLV2-18 2015 -2963
IGLV2-23 2029 -4201
IGLV2-8 4818 -5256
IGLV3-1 -96 -5140
IGLV3-12 -7299 -6816
IGLV3-19 4006 -5611
IGLV3-21 -975 -6062
IGLV3-25 -942 -5485
IGLV3-27 -5365 -4834
IGLV4-69 1344 -2261
IGLV5-45 4194 -7364
IGLV6-57 1834 -5837
IGLV7-43 4854 -2823
IGLV7-46 2445 -3619
IGLV8-61 -3989 -5208
PROS1 9065 7937
SERPING1 -6329 -10968
VTN -5291 730



Complement cascade

Complement cascade
metric value
setSize 97
pMANOVA 1.56e-12
p.adjustMANOVA 4.61e-11
s.dist 0.269
s.low.CRP 0.201
s.high.CRP -0.179
p.low.CRP 0.000633
p.high.CRP 0.00233




Top 20 genes
Gene low CRP high CRP
IGKV3-11 5548 -7167
IGKV1-33 5955 -6384
IGKV1-16 6217 -5451
IGKV1-5 6127 -5162
IGLV5-45 4194 -7364
IGHV3-23 6032 -5092
IGKV2-30 5205 -5349
IGLV1-44 4742 -5791
IGHV4-59 4532 -5870
IGLV2-8 4818 -5256
IGHV4-39 3786 -6542
IGLV3-19 4006 -5611
IGHV1-2 5956 -3146
IGKV3-20 3704 -5021
IGKC 2773 -6437
IGLV1-36 3522 -5030
C4BPB 3624 -4862
IGHV3-11 3518 -4591
IGHV3-7 4185 -3630
IGKV3-15 3174 -4687

Click HERE to show all gene set members

All member genes
low CRP high CRP
C1QA -49 7890
C1QB 6746 8930
C1QC 7805 9340
C1R -10393 -4020
C1S -6159 552
C2 6634 2959
C3 -11179 -10489
C3AR1 8924 8181
C4A 5060 4740
C4B 6359 2884
C4BPB 3624 -4862
C5 7727 2354
C5AR1 9359 9709
C5AR2 8198 8666
C8G -10839 -8035
CD19 -2992 -2929
CD46 8744 5145
CD55 9326 9842
CD59 4075 5772
CD81 -10685 -3573
CFB -3014 -2968
CFD 2998 2390
CFH -3147 -6338
CLU 9512 10102
CPN2 8266 1159
CR1 10079 10078
CR2 -1342 -3900
ELANE 9880 4888
FCN1 9889 9103
GZMM -11118 -8768
IGHG1 -1124 -7111
IGHG2 -5587 -6004
IGHG3 -507 -4089
IGHG4 -4038 -5940
IGHV1-2 5956 -3146
IGHV1-46 3766 -2976
IGHV1-69 2354 -2328
IGHV2-5 4451 -1972
IGHV2-70 -3315 -2159
IGHV3-11 3518 -4591
IGHV3-13 799 -2451
IGHV3-23 6032 -5092
IGHV3-30 2500 -5193
IGHV3-33 98 -4138
IGHV3-48 3183 -4340
IGHV3-53 3131 -1786
IGHV3-7 4185 -3630
IGHV4-34 1144 -4007
IGHV4-39 3786 -6542
IGHV4-59 4532 -5870
IGKC 2773 -6437
IGKV1-12 725 -6674
IGKV1-16 6217 -5451
IGKV1-17 -241 -2794
IGKV1-33 5955 -6384
IGKV1-5 6127 -5162
IGKV1D-39 5018 -2677
IGKV2-28 1440 -6662
IGKV2-30 5205 -5349
IGKV2D-28 -7224 -2947
IGKV3-11 5548 -7167
IGKV3-15 3174 -4687
IGKV3-20 3704 -5021
IGKV3D-20 -1830 -4618
IGKV4-1 2812 -4988
IGKV5-2 5226 -2682
IGLC1 -2813 -6176
IGLC2 -258 -6539
IGLC3 -2958 -4378
IGLC7 -3403 -4490
IGLV1-36 3522 -5030
IGLV1-40 163 -5497
IGLV1-44 4742 -5791
IGLV1-47 231 -6633
IGLV1-51 1708 -6601
IGLV10-54 -5422 316
IGLV2-11 870 -3205
IGLV2-14 -5127 -8197
IGLV2-18 2015 -2963
IGLV2-23 2029 -4201
IGLV2-8 4818 -5256
IGLV3-1 -96 -5140
IGLV3-12 -7299 -6816
IGLV3-19 4006 -5611
IGLV3-21 -975 -6062
IGLV3-25 -942 -5485
IGLV3-27 -5365 -4834
IGLV4-69 1344 -2261
IGLV5-45 4194 -7364
IGLV6-57 1834 -5837
IGLV7-43 4854 -2823
IGLV7-46 2445 -3619
IGLV8-61 -3989 -5208
MASP2 2089 -6883
PROS1 9065 7937
SERPING1 -6329 -10968
VTN -5291 730



Role of phospholipids in phagocytosis

Role of phospholipids in phagocytosis
metric value
setSize 87
pMANOVA 3.18e-12
p.adjustMANOVA 9.22e-11
s.dist 0.29
s.low.CRP 0.135
s.high.CRP -0.257
p.low.CRP 0.0301
p.high.CRP 3.51e-05




Top 20 genes
Gene low CRP high CRP
IGKV3-11 5548 -7167
IGKV1-33 5955 -6384
IGKV1-16 6217 -5451
IGKV1-5 6127 -5162
IGLV5-45 4194 -7364
IGHV3-23 6032 -5092
IGKV2-30 5205 -5349
IGLV1-44 4742 -5791
IGHV4-59 4532 -5870
IGLV2-8 4818 -5256
IGHV4-39 3786 -6542
IGLV3-19 4006 -5611
IGHV1-2 5956 -3146
IGKV3-20 3704 -5021
IGKC 2773 -6437
IGLV1-36 3522 -5030
IGHV3-11 3518 -4591
IGHV3-7 4185 -3630
IGKV3-15 3174 -4687
IGKV4-1 2812 -4988

Click HERE to show all gene set members

All member genes
low CRP high CRP
AHCYL1 6114 7566
CD247 -11271 -10327
CD3G -9054 -10504
FCGR1A 9965 9575
FCGR2A 9414 9249
FCGR3A -11272 -4672
IGHG1 -1124 -7111
IGHG2 -5587 -6004
IGHG3 -507 -4089
IGHG4 -4038 -5940
IGHV1-2 5956 -3146
IGHV1-46 3766 -2976
IGHV1-69 2354 -2328
IGHV2-5 4451 -1972
IGHV2-70 -3315 -2159
IGHV3-11 3518 -4591
IGHV3-13 799 -2451
IGHV3-23 6032 -5092
IGHV3-30 2500 -5193
IGHV3-33 98 -4138
IGHV3-48 3183 -4340
IGHV3-53 3131 -1786
IGHV3-7 4185 -3630
IGHV4-34 1144 -4007
IGHV4-39 3786 -6542
IGHV4-59 4532 -5870
IGKC 2773 -6437
IGKV1-12 725 -6674
IGKV1-16 6217 -5451
IGKV1-17 -241 -2794
IGKV1-33 5955 -6384
IGKV1-5 6127 -5162
IGKV1D-39 5018 -2677
IGKV2-28 1440 -6662
IGKV2-30 5205 -5349
IGKV2D-28 -7224 -2947
IGKV3-11 5548 -7167
IGKV3-15 3174 -4687
IGKV3-20 3704 -5021
IGKV3D-20 -1830 -4618
IGKV4-1 2812 -4988
IGKV5-2 5226 -2682
IGLC1 -2813 -6176
IGLC2 -258 -6539
IGLC3 -2958 -4378
IGLC7 -3403 -4490
IGLV1-36 3522 -5030
IGLV1-40 163 -5497
IGLV1-44 4742 -5791
IGLV1-47 231 -6633
IGLV1-51 1708 -6601
IGLV10-54 -5422 316
IGLV2-11 870 -3205
IGLV2-14 -5127 -8197
IGLV2-18 2015 -2963
IGLV2-23 2029 -4201
IGLV2-8 4818 -5256
IGLV3-1 -96 -5140
IGLV3-12 -7299 -6816
IGLV3-19 4006 -5611
IGLV3-21 -975 -6062
IGLV3-25 -942 -5485
IGLV3-27 -5365 -4834
IGLV4-69 1344 -2261
IGLV5-45 4194 -7364
IGLV6-57 1834 -5837
IGLV7-43 4854 -2823
IGLV7-46 2445 -3619
IGLV8-61 -3989 -5208
ITPR1 -5546 -5368
ITPR2 6833 6418
ITPR3 -8438 -9066
PIK3CA 6889 4182
PIK3CB 9838 9248
PIK3R1 -7197 -8942
PIK3R2 2459 5820
PLA2G6 -10753 -10993
PLCG1 -6360 -11043
PLCG2 -4618 6826
PLD1 9826 9945
PLD2 7087 7779
PLD3 8640 7098
PLD4 -11266 -11216
PLPP5 -4861 -6194
PRKCD 9393 9642
PRKCE -10383 -2720
SYK 9464 9848



Intra-Golgi and retrograde Golgi-to-ER traffic

Intra-Golgi and retrograde Golgi-to-ER traffic
metric value
setSize 179
pMANOVA 7.3e-12
p.adjustMANOVA 2.07e-10
s.dist 0.351
s.low.CRP 0.167
s.high.CRP 0.309
p.low.CRP 0.000116
p.high.CRP 1e-12




Top 20 genes
Gene low CRP high CRP
PLIN3 9856 10099
PLA2G4A 9622 10024
ARF4 9859 9444
KDELR1 9552 9681
RAB1A 9700 9407
CUX1 8954 9964
STX10 9426 9350
NSF 8895 9680
DCTN2 8504 10012
ARF1 8465 9910
TGOLN2 8606 9683
GALNT2 8571 9697
CAPZA2 9698 8474
BICD2 8006 9959
KIF5B 9540 8103
DCTN4 7967 9572
VAMP3 9204 8284
CAPZA1 8666 8511
KIF1B 8577 8548
RAB6A 8487 8616

Click HERE to show all gene set members

All member genes
low CRP high CRP
ACTR10 8589 7569
ACTR1A -2833 8680
AGPAT3 6352 4771
ARCN1 4082 6402
ARF1 8465 9910
ARF3 5651 9049
ARF4 9859 9444
ARF5 5736 9180
ARFGAP1 -6136 2991
ARFGAP2 -8987 2096
ARFGAP3 -6040 5157
ARFIP2 -2956 -529
ARFRP1 -8821 -1241
ARL1 433 -3992
BET1L -7832 -2582
BICD1 -8225 -5006
BICD2 8006 9959
BNIP1 -3293 -5463
CAPZA1 8666 8511
CAPZA2 9698 8474
CAPZB 6100 8926
CENPE -3467 886
COG1 -10399 -10838
COG2 -1210 -5915
COG3 3891 -5333
COG4 -4813 2002
COG5 1617 -3368
COG6 1512 -6280
COG7 2191 6149
COG8 -2814 2839
COPA 7617 9591
COPB1 8213 7283
COPB2 8531 8034
COPE 365 8719
COPG1 2542 9195
COPG2 7905 8313
COPZ1 2549 5017
COPZ2 -9229 -9247
CUX1 8954 9964
CYTH1 -11020 -10918
CYTH2 -5796 4527
CYTH3 -10332 -415
CYTH4 -3373 7558
DCTN1 -5984 7873
DCTN2 8504 10012
DCTN3 325 7904
DCTN4 7967 9572
DCTN5 -7505 664
DCTN6 7871 7759
DYNC1H1 -8881 -2533
DYNC1I1 7141 2722
DYNC1I2 8160 8196
DYNC1LI1 7894 6997
DYNC1LI2 3494 5636
DYNLL1 6026 6499
DYNLL2 -6325 -225
GALNT1 7249 6590
GALNT2 8571 9697
GBF1 -8933 1807
GCC1 -1592 4456
GCC2 2224 -8694
GOLGA1 -8499 4971
GOLGA4 -783 -4010
GOLGA5 6321 5485
GOLIM4 1630 7798
GOSR1 -4021 2971
GOSR2 -2437 1468
IGF2R -1133 9240
KDELR1 9552 9681
KDELR2 8771 7531
KDELR3 2255 -3318
KIF11 -140 1030
KIF13B 1563 7357
KIF15 -4399 -3471
KIF16B 4416 3004
KIF18A -5118 -1862
KIF18B -3932 1641
KIF19 -10944 -8869
KIF1B 8577 8548
KIF1C 6981 8811
KIF20A 5368 4706
KIF20B -962 -8226
KIF21A -10337 -10254
KIF21B -10698 -135
KIF22 -10995 -11246
KIF23 8000 4957
KIF26A -155 -6527
KIF26B -10618 -9336
KIF27 5469 1812
KIF28P -7127 -4560
KIF2A 2515 -1329
KIF2C 2032 104
KIF3A -9378 -11000
KIF3B 3757 4323
KIF3C 7590 9010
KIF4A -1703 4331
KIF5A -7037 -7903
KIF5B 9540 8103
KIF5C -2924 -10718
KIF6 2741 806
KIF9 -1185 6392
KIFAP3 -8849 -4476
KIFC1 -3213 1241
KIFC2 -900 -938
KLC1 1745 7386
KLC2 -6674 -7322
KLC3 8390 7398
KLC4 -9223 -3527
M6PR -7566 -3638
MAN1A1 4965 9297
MAN1A2 -1459 -993
MAN1C1 1436 -8761
MAN2A1 5542 -2948
MAN2A2 1864 8354
NAA30 -5891 -7939
NAA35 -9061 -9861
NAA38 3081 9471
NAPA -2447 3305
NAPB -291 -2004
NAPG 7409 3591
NBAS 1380 1565
NSF 8895 9680
PAFAH1B1 -336 6894
PAFAH1B2 7693 7761
PAFAH1B3 5824 4526
PLA2G4A 9622 10024
PLA2G6 -10753 -10993
PLIN3 9856 10099
RAB18 9425 7287
RAB1A 9700 9407
RAB1B 5676 9455
RAB30 -7367 -8558
RAB33B 8756 6897
RAB36 651 6588
RAB39A 8587 6613
RAB3GAP1 8630 5252
RAB3GAP2 4746 4797
RAB41 -20 -4213
RAB43 4478 7506
RAB6A 8487 8616
RAB6B 6925 6712
RAB9A 2889 5200
RAB9B -5682 -4620
RABEPK -1567 7092
RACGAP1 3340 3770
RGP1 -2026 6446
RHOBTB3 -11228 -2363
RIC1 7981 6900
RINT1 1211 -10524
SCOC 7819 -5600
SEC22B 8663 4943
SNAP29 -1741 8902
STX10 9426 9350
STX16 5855 4189
STX18 566 6529
STX5 3566 8258
STX6 7335 9578
SURF4 3781 8016
SYS1 -2469 2886
TGOLN2 8606 9683
TMED10 35 2168
TMED2 6426 6360
TMED3 -2098 4751
TMED7 9038 7918
TMED9 917 9007
TMF1 5973 2223
TRIP11 5087 -2116
USE1 1304 2460
USP6NL 8168 3185
VAMP3 9204 8284
VAMP4 7662 1445
VPS45 6527 1884
VPS51 -8466 -1916
VPS52 -4410 -725
VPS53 -4323 2773
VPS54 9119 6993
VTI1A -2998 7207
YKT6 -3724 6818
ZW10 5778 -752



Signaling by WNT

Signaling by WNT
metric value
setSize 253
pMANOVA 9.98e-12
p.adjustMANOVA 2.74e-10
s.dist 0.283
s.low.CRP 0.121
s.high.CRP 0.256
p.low.CRP 0.000901
p.high.CRP 2.45e-12




Top 20 genes
Gene low CRP high CRP
FZD5 10104 10128
SNX3 9914 9837
GNG10 9939 9753
H2BC21 9852 9656
AGO4 9771 9580
WNT11 9481 9830
FRAT2 9692 9464
CLTC 9376 9720
H2AJ 8999 10117
KREMEN1 8950 9970
H2BC12 9066 9812
PLCB3 8806 9909
RAC1 9052 9614
H3-3A 9297 9034
GNG5 8894 9403
RNF146 8442 9760
FRAT1 8396 9480
PPP3R1 8998 8570
CLTA 8416 8998
PSME3 9120 8239

Click HERE to show all gene set members

All member genes
low CRP high CRP
AGO1 2933.0 7911.0
AGO2 2783.0 4361.0
AGO3 5298.0 -2808.0
AGO4 9771.0 9580.0
AKT1 -4794.0 6231.0
AKT2 -8391.0 5504.0
AMER1 -9251.0 -9464.0
AP2A1 -3194.0 9104.0
AP2A2 3196.0 9217.0
AP2B1 -9145.0 2444.0
AP2M1 7742.0 9334.0
AP2S1 7422.0 8877.0
APC 3083.0 3959.0
ARRB2 7827.0 9274.0
ASH2L 2845.0 6972.0
AXIN1 -10901.0 -2157.0
AXIN2 1014.0 -9374.0
BCL9 -2052.0 216.0
BCL9L -10522.0 -10404.0
BTRC -6845.0 -441.0
CALM1 -6645.0 1321.0
CAV1 2492.0 1598.0
CBY1 -3580.0 -9677.0
CCDC88C -11013.0 -9133.0
CDC73 5065.0 5233.0
CHD8 -7984.0 4518.0
CLTA 8416.0 8998.0
CLTB -2857.0 8274.0
CLTC 9376.0 9720.0
CREBBP -4951.0 6023.0
CSNK1A1 8062.0 8483.0
CSNK1E -9947.0 -6531.0
CSNK1G2 -8130.0 4845.0
CSNK2A1 3192.0 8248.0
CSNK2A2 6050.0 7886.0
CSNK2B 1222.0 5287.0
CTBP1 -10319.0 2597.0
CTBP2 -8332.0 7583.0
CTNNB1 3201.0 7613.0
CTNNBIP1 5853.0 8471.0
CUL1 -2085.0 -10951.0
CUL3 7151.0 7368.0
CXXC4 -10472.0 -2258.0
DAAM1 4929.0 3983.0
DACT1 7172.0 -2602.0
DVL1 -1093.0 1894.0
DVL2 -10305.0 -7147.0
DVL3 -4437.0 8389.0
EP300 4311.0 7552.0
FRAT1 8396.0 9480.0
FRAT2 9692.0 9464.0
FZD1 -468.0 5900.0
FZD2 6675.0 7410.0
FZD3 -374.0 -7373.0
FZD4 -10858.0 -7985.0
FZD5 10104.0 10128.0
FZD6 -304.0 -7933.0
FZD7 -3752.0 -6423.0
FZD8 -9255.0 -2577.0
GNAO1 -10349.0 -6203.0
GNAT2 6387.0 7579.0
GNB1 6908.0 9175.0
GNB2 6587.0 9064.0
GNB3 7806.0 -8406.0
GNB4 9340.0 6537.0
GNB5 6182.0 -475.0
GNG10 9939.0 9753.0
GNG11 8239.0 6403.0
GNG2 -10761.0 192.0
GNG3 4993.0 -794.0
GNG4 414.0 -2445.0
GNG5 8894.0 9403.0
GNG7 -2881.0 -4054.0
GNG8 4092.0 4604.0
GNGT2 -11227.0 -6988.0
GSK3B 6119.0 7526.0
H2AC20 -790.0 6112.0
H2AC6 8700.0 8169.0
H2AJ 8999.0 10117.0
H2AZ1 1779.0 7321.0
H2AZ2 -4042.0 2210.0
H2BC11 8424.0 8288.0
H2BC12 9066.0 9812.0
H2BC15 3036.0 6455.0
H2BC17 7882.0 7312.0
H2BC21 9852.0 9656.0
H2BC4 7156.0 7805.0
H2BC5 7596.0 8773.0
H2BC9 7965.0 4715.0
H2BU1 -6349.0 -3895.0
H3-3A 9297.0 9034.0
H3C15 5262.5 7402.5
HDAC1 -3835.0 3708.0
ITPR1 -5546.0 -5368.0
ITPR2 6833.0 6418.0
ITPR3 -8438.0 -9066.0
KAT5 -7070.0 4899.0
KLHL12 4669.0 8766.0
KMT2D -2369.0 5062.0
KRAS 3789.0 4070.0
KREMEN1 8950.0 9970.0
KREMEN2 -6004.0 4016.0
LEF1 4722.0 -10841.0
LEO1 6728.0 -1045.0
LGR4 3548.0 2777.0
LGR6 -11188.0 -9867.0
LRP5 5683.0 4611.0
LRP6 3999.0 -1401.0
MAP3K7 1546.0 4274.0
MEN1 -8589.0 -4575.0
MOV10 -10256.0 -10510.0
MYC 8429.0 -2186.0
NFATC1 -9648.0 -4795.0
NLK 3383.0 3944.0
PARD6A -1188.0 1317.0
PDE6A 5612.0 -5655.0
PDE6B -9215.0 -10116.0
PDE6G -9811.0 4921.0
PFN1 -5663.0 7801.0
PIP5K1B 5094.0 7192.0
PLCB1 1989.0 1657.0
PLCB2 2249.0 5858.0
PLCB3 8806.0 9909.0
PORCN -9834.0 -6886.0
PPP2CA 8810.0 8328.0
PPP2CB 8482.0 7631.0
PPP2R1A -3087.0 6994.0
PPP2R1B 2503.0 437.0
PPP2R5A -903.0 6957.0
PPP2R5B 5288.0 7952.0
PPP2R5C -10420.0 -7112.0
PPP2R5D -6508.0 4985.0
PPP2R5E 715.0 540.0
PPP3CA 6208.0 7300.0
PPP3CB 8057.0 6833.0
PPP3R1 8998.0 8570.0
PRICKLE1 6870.0 800.0
PRKCA 2473.0 1229.0
PRKCB 5395.0 8378.0
PRKG1 8854.0 5968.0
PRKG2 -7602.0 -7604.0
PSMA1 8278.0 7406.0
PSMA2 5830.0 5666.0
PSMA3 4646.0 -7621.0
PSMA4 3950.0 -1036.0
PSMA5 -2119.0 -3983.0
PSMA6 6893.0 5865.0
PSMA7 3550.0 8554.0
PSMB1 3915.0 4224.0
PSMB10 -7878.0 -1272.0
PSMB2 2664.0 4928.0
PSMB3 4971.0 8382.0
PSMB4 -3175.0 4911.0
PSMB5 6561.0 9138.0
PSMB6 1312.0 8784.0
PSMB7 8034.0 9051.0
PSMB8 -4481.0 75.0
PSMB9 -9105.0 -10433.0
PSMC1 6759.0 7782.0
PSMC2 -2524.0 4517.0
PSMC3 -4971.0 4984.0
PSMC4 -10757.0 -336.0
PSMC5 -3424.0 2764.0
PSMC6 8812.0 6000.0
PSMD1 7679.0 7587.0
PSMD10 2067.0 2450.0
PSMD11 6914.0 6824.0
PSMD12 9011.0 5710.0
PSMD13 3157.0 7205.0
PSMD14 2891.0 3041.0
PSMD2 4352.0 8396.0
PSMD3 -2243.0 6367.0
PSMD4 6858.0 9449.0
PSMD5 2770.0 4781.0
PSMD6 8841.0 8304.0
PSMD7 6534.0 6147.0
PSMD8 739.0 7117.0
PSMD9 3580.0 9001.0
PSME1 -7256.0 -7913.0
PSME2 -5548.0 -10355.0
PSME3 9120.0 8239.0
PSME4 -5205.0 -3127.0
PSMF1 6709.0 6770.0
PYGO2 -9829.0 -8073.0
RAC1 9052.0 9614.0
RAC2 -7677.0 6828.0
RAC3 -4395.0 -1033.0
RBBP5 4931.0 173.0
RBX1 1418.0 4877.0
RHOA 8351.0 8888.0
RNF146 8442.0 9760.0
RNF43 -9524.0 -11210.0
ROR1 2411.0 -2323.0
RPS27A -3555.0 -7070.0
RUNX3 -11261.0 -9989.0
RUVBL1 -5940.0 -5741.0
RYK -835.0 -9020.0
SCRIB -8867.0 2824.0
SEM1 993.0 5942.0
SKP1 8120.0 2700.0
SMARCA4 -2731.0 7803.0
SMURF1 -9318.0 2452.0
SMURF2 -9128.0 -7045.0
SNX3 9914.0 9837.0
SOX13 -10748.0 -8557.0
SOX4 5490.0 5191.0
SOX6 8955.0 3557.0
SOX7 2991.0 -6140.0
TCF4 -6491.0 -2021.0
TCF7 -2790.0 -11149.0
TCF7L1 -1964.0 2145.0
TCF7L2 -10402.0 -1302.0
TERT 8288.0 -4814.0
TLE1 -10867.0 400.0
TLE2 3990.0 -9885.0
TLE3 6965.0 9696.0
TLE4 2341.0 8265.0
TLE5 -10837.0 -9839.0
TMED5 8987.0 6292.0
TNKS -7769.0 -6024.0
TNKS2 604.0 1179.0
TNRC6A -831.0 -4972.0
TNRC6B -4840.0 -2293.0
TNRC6C -10738.0 -9183.0
TRRAP -7730.0 -2671.0
UBA52 -1875.0 3023.0
UBB 8251.0 6157.0
UBC -1915.0 5825.0
USP34 -268.0 385.0
USP8 8542.0 6497.0
VPS26A 7873.0 6528.0
VPS29 5940.0 2690.0
VPS35 8235.0 6328.0
WLS 9595.0 7423.0
WNT1 -7238.0 -8407.0
WNT10A -6531.0 -8450.0
WNT10B -9917.0 -7977.0
WNT11 9481.0 9830.0
WNT16 -6468.0 -3003.0
WNT2B -3933.0 -2393.0
WNT3 -6507.0 -2617.0
WNT4 -5401.0 -2168.0
WNT5B -1354.0 1462.0
WNT6 6264.0 5014.0
WNT7A 1684.0 -10965.0
WNT8B -803.0 -2558.0
WNT9A -4952.0 -3203.0
WNT9B -3400.0 3438.0
XIAP 2120.0 1654.0
XPO1 6563.0 -3235.0
YWHAZ 5165.0 5861.0
ZNRF3 3239.0 -4029.0
ZRANB1 4893.0 3821.0



Class I MHC mediated antigen processing & presentation

Class I MHC mediated antigen processing & presentation
metric value
setSize 347
pMANOVA 1e-11
p.adjustMANOVA 2.74e-10
s.dist 0.236
s.low.CRP 0.0937
s.high.CRP 0.217
p.low.CRP 0.00272
p.high.CRP 4.12e-12




Top 20 genes
Gene low CRP high CRP
FBXO9 10081 9997
SOCS3 9830 10110
CD36 10064 9814
FBXL5 10052 9713
NCF4 9697 9856
KLHL2 9929 9615
FCGR1A 9965 9575
NCF2 9748 9694
UBE2D1 9825 9491
CD14 9551 9658
TLR4 9494 9617
UBE2J1 10056 9062
TLR2 9930 9118
FCGR1B 9834 9178
TLR6 9634 9209
TRIM71 9234 9601
CYBB 9900 8910
TLR1 9828 8868
LY96 9529 8995
MKRN1 9789 8565

Click HERE to show all gene set members

All member genes
low CRP high CRP
ANAPC1 -9718 -10978
ANAPC10 -4639 -2175
ANAPC11 3528 7783
ANAPC13 6822 1501
ANAPC2 -6824 -4561
ANAPC4 1210 -8491
ANAPC5 -8996 -8730
ANAPC7 -4282 -1578
AREL1 -2744 8240
ARIH2 -10965 -8339
ASB1 -7632 6070
ASB13 3848 3880
ASB14 4303 -4544
ASB16 -8746 -2220
ASB2 -10926 -8940
ASB3 4105 1485
ASB4 -5055 -4525
ASB6 -7877 2463
ASB7 7450 6094
ASB8 823 6079
ASB9 4472 -207
ATG7 9062 8455
B2M -4257 -4660
BLMH 3784 3710
BTBD1 6622 1719
BTBD6 -7724 -284
BTK 7623 7870
BTRC -6845 -441
CALR 6685 6374
CANX 6838 5751
CBLB -11028 -10771
CCNF -10194 -4195
CD14 9551 9658
CD36 10064 9814
CDC16 -858 -5118
CDC20 -74 5136
CDC23 -7178 -9273
CDC26 3465 3689
CDC27 1988 -5
CDC34 8212 9329
CHUK 9198 7663
CTSL -5538 5895
CTSS 9854 7280
CTSV -1271 -2930
CUL1 -2085 -10951
CUL2 6801 1682
CUL3 7151 7368
CUL5 7502 -2980
CUL7 -8296 2248
CYBA -48 8901
CYBB 9900 8910
DET1 -2495 -9884
DTX3L 1603 -4629
DZIP3 -6745 -10932
ELOB 4867 8716
ELOC 6598 8484
ERAP1 -3226 -6281
ERAP2 -2069 -5352
FBXL12 -4301 2284
FBXL13 2462 5869
FBXL14 -6789 -2829
FBXL15 1462 6096
FBXL16 2754 -10861
FBXL18 -5426 6339
FBXL19 7149 9883
FBXL20 6138 5443
FBXL22 -8336 -7072
FBXL3 2372 1555
FBXL4 8476 5165
FBXL5 10052 9713
FBXL8 6606 3297
FBXO10 -9543 -2014
FBXO11 8518 6652
FBXO15 -57 -1454
FBXO17 6660 2069
FBXO2 -8087 -5594
FBXO21 -8475 -8331
FBXO22 4093 -5449
FBXO27 -4715 -3768
FBXO30 5887 4626
FBXO31 -10431 -10713
FBXO32 -9356 -10029
FBXO4 -7804 -11129
FBXO40 -216 3482
FBXO41 -3899 1696
FBXO44 -7880 -8023
FBXO6 -7080 1208
FBXO7 9298 6606
FBXO9 10081 9997
FBXW11 4585 7364
FBXW12 -7896 -6549
FBXW2 544 8055
FBXW4 -10467 -8565
FBXW5 -9273 5091
FBXW7 -5277 -3657
FBXW8 -9427 -6871
FBXW9 -10047 -416
FCGR1A 9965 9575
FCGR1B 9834 9178
FZR1 -7787 2875
GAN 203 -1098
GLMN -2858 -11010
HACE1 -2041 -5105
HECTD1 -2628 226
HECTD2 -9466 -6054
HECTD3 -7244 4993
HECW2 -2797 5962
HERC1 -8668 -6166
HERC2 -10344 -6770
HERC3 -1108 2890
HERC4 8554 4015
HERC5 -10767 -10994
HERC6 -10910 -10777
HLA-A -5067 570
HLA-B -1559 1570
HLA-C -2829 2125
HLA-E -10409 2003
HLA-F -10598 -7440
HLA-G -5051 159
HLA-H -8161 452
HSPA5 8070 6713
HUWE1 -8883 -3494
IKBKB -5276 -2118
IKBKG -3058 7903
ITCH -2889 3792
ITGAV 7467 6188
ITGB5 7729 7327
KBTBD6 -1477 2862
KBTBD7 3626 6975
KBTBD8 -1867 -3245
KCTD6 4870 5068
KCTD7 -9176 -10293
KEAP1 -3358 7274
KLHL11 -2734 -5716
KLHL2 9929 9615
KLHL20 -9314 -9256
KLHL21 663 6548
KLHL22 -10423 -8088
KLHL25 -9206 -9406
KLHL3 -8309 -11239
KLHL42 -4575 -7103
KLHL5 9255 2537
KLHL9 1973 2194
LMO7 -3935 -10042
LNPEP -8634 -6784
LNX1 7669 -9609
LONRF1 1750 5533
LRR1 -7801 -3939
LRRC41 5384 8643
LRSAM1 -1526 6741
LTN1 4330 -4383
LY96 9529 8995
MEX3C -11104 -8577
MGRN1 1713 6976
MIB2 -10461 -7734
MKRN1 9789 8565
MRC1 -6259 4719
MRC2 4574 -2049
MYD88 8651 8344
MYLIP -4440 -1671
NCF1 8576 7083
NCF2 9748 9694
NCF4 9697 9856
NEDD4 -884 7132
NEDD4L 8246 8260
NPEPPS 9087 8223
PDIA3 2037 4838
PJA1 -8316 -7296
PJA2 7725 7785
PSMA1 8278 7406
PSMA2 5830 5666
PSMA3 4646 -7621
PSMA4 3950 -1036
PSMA5 -2119 -3983
PSMA6 6893 5865
PSMA7 3550 8554
PSMB1 3915 4224
PSMB10 -7878 -1272
PSMB2 2664 4928
PSMB3 4971 8382
PSMB4 -3175 4911
PSMB5 6561 9138
PSMB6 1312 8784
PSMB7 8034 9051
PSMB8 -4481 75
PSMB9 -9105 -10433
PSMC1 6759 7782
PSMC2 -2524 4517
PSMC3 -4971 4984
PSMC4 -10757 -336
PSMC5 -3424 2764
PSMC6 8812 6000
PSMD1 7679 7587
PSMD10 2067 2450
PSMD11 6914 6824
PSMD12 9011 5710
PSMD13 3157 7205
PSMD14 2891 3041
PSMD2 4352 8396
PSMD3 -2243 6367
PSMD4 6858 9449
PSMD5 2770 4781
PSMD6 8841 8304
PSMD7 6534 6147
PSMD8 739 7117
PSMD9 3580 9001
PSME1 -7256 -7913
PSME2 -5548 -10355
PSME3 9120 8239
PSME4 -5205 -3127
PSMF1 6709 6770
RBBP6 7135 -3752
RBCK1 -4700 4686
RBX1 1418 4877
RCHY1 8112 5797
RLIM 5748 5413
RNF111 6509 6215
RNF114 6745 2760
RNF115 -9065 -5995
RNF123 3943 8163
RNF126 -9628 -7680
RNF130 8891 9015
RNF138 8936 2161
RNF14 3011 5025
RNF144B 8927 8721
RNF19A -8656 -6854
RNF19B 7545 6682
RNF213 -10439 -9870
RNF217 9908 7097
RNF220 -9365 739
RNF25 -8613 -1512
RNF34 -7739 -719
RNF4 -10891 -3374
RNF41 8699 9075
RNF6 5905 3868
RNF7 6703 8617
RPS27A -3555 -7070
SAR1B 8795 5984
SEC13 2125 6861
SEC22B 8663 4943
SEC23A 8776 6905
SEC24A 8318 7788
SEC24B 1663 5398
SEC24C -9662 3561
SEC24D 8017 8795
SEC31A 1743 2474
SEC61A1 5496 7020
SEC61A2 -8826 -9671
SEC61B 4953 8362
SEC61G 7533 3614
SEM1 993 5942
SH3RF1 -7501 -1839
SIAH1 -5833 454
SIAH2 9783 8092
SKP1 8120 2700
SKP2 -2615 -7161
SMURF1 -9318 2452
SMURF2 -9128 -7045
SNAP23 9586 8642
SOCS1 -219 6051
SOCS3 9830 10110
SPSB1 -2844 4000
SPSB2 -9283 1413
STUB1 -7516 3468
STX4 -7285 5736
TAP1 -8207 -9297
TAP2 -9895 -10077
TAPBP -5450 4788
THOP1 -8479 -6598
TIRAP 262 7730
TLR1 9828 8868
TLR2 9930 9118
TLR4 9494 9617
TLR6 9634 9209
TPP2 1634 -9998
TRAF7 6671 9722
TRAIP -10021 -9806
TRIM11 -8090 2058
TRIM21 1612 3394
TRIM32 -10314 -9171
TRIM36 -5451 -4846
TRIM37 -4576 -5985
TRIM39 -10551 -4566
TRIM4 4607 2467
TRIM41 -7799 6954
TRIM69 -6071 -8400
TRIM71 9234 9601
TRIM9 263 1863
TRIP12 5055 8104
UBA1 2505 8454
UBA3 9502 7030
UBA5 2339 -9858
UBA52 -1875 3023
UBA6 4933 3279
UBA7 -5544 -5471
UBAC1 8616 8637
UBB 8251 6157
UBC -1915 5825
UBE2A 7726 8032
UBE2B 8648 6410
UBE2C 3717 5687
UBE2D1 9825 9491
UBE2D2 2673 5593
UBE2D3 9443 8783
UBE2D4 -5562 -10226
UBE2E1 8528 6289
UBE2E2 6610 -195
UBE2E3 5727 5064
UBE2F 960 8586
UBE2G1 3646 5958
UBE2G2 719 -9159
UBE2H 7660 8041
UBE2J1 10056 9062
UBE2J2 7098 9468
UBE2K 8831 6196
UBE2L3 7416 7794
UBE2L6 -8809 -9855
UBE2M 2776 9251
UBE2N 4087 2050
UBE2O 3953 2699
UBE2Q1 2002 6541
UBE2Q2 -8213 -9964
UBE2R2 8380 9338
UBE2S 3693 5680
UBE2V1 6665 5995
UBE2V2 6427 1996
UBE2W 9632 7147
UBE2Z -9598 -6520
UBE3A 5897 2802
UBE3B -1608 4236
UBE3C 7039 6246
UBE3D -7298 -9854
UBE4A 2454 2894
UBOX5 -8909 4492
UBR1 -5289 -1585
UBR2 3389 5400
UBR4 -6416 1703
UFL1 -708 -6987
UNKL -4160 292
VAMP3 9204 8284
VAMP8 2890 6767
VHL -212 6007
WSB1 8808 8048
WWP1 813 -10536
ZBTB16 -9729 5951
ZNRF1 8449 8470
ZNRF2 -598 2800



Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.0.3 (2020-10-10)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 18.04.5 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.7.1
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.7.1
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.1.0               GGally_2.0.0               
##  [3] beeswarm_0.2.3              gtools_3.8.2               
##  [5] echarts4r_0.3.3             eulerr_6.1.0               
##  [7] mitch_1.2.2                 MASS_7.3-53                
##  [9] fgsea_1.16.0                gplots_3.1.0               
## [11] DESeq2_1.30.0               SummarizedExperiment_1.20.0
## [13] Biobase_2.50.0              MatrixGenerics_1.2.0       
## [15] matrixStats_0.57.0          GenomicRanges_1.42.0       
## [17] GenomeInfoDb_1.26.0         IRanges_2.24.0             
## [19] S4Vectors_0.28.0            BiocGenerics_0.36.0        
## [21] reshape2_1.4.4              forcats_0.5.0              
## [23] stringr_1.4.0               dplyr_1.0.2                
## [25] purrr_0.3.4                 readr_1.4.0                
## [27] tidyr_1.1.2                 tibble_3.0.4               
## [29] ggplot2_3.3.2               tidyverse_1.3.0            
## 
## loaded via a namespace (and not attached):
##  [1] colorspace_2.0-0       ellipsis_0.3.1         rprojroot_1.3-2       
##  [4] XVector_0.30.0         fs_1.5.0               rstudioapi_0.12       
##  [7] farver_2.0.3           bit64_4.0.5            AnnotationDbi_1.52.0  
## [10] fansi_0.4.1            lubridate_1.7.9        xml2_1.3.2            
## [13] splines_4.0.3          geneplotter_1.68.0     knitr_1.30            
## [16] polyclip_1.10-0        jsonlite_1.7.1         broom_0.7.2           
## [19] annotate_1.68.0        dbplyr_2.0.0           shiny_1.5.0           
## [22] compiler_4.0.3         httr_1.4.2             backports_1.2.0       
## [25] assertthat_0.2.1       Matrix_1.2-18          fastmap_1.0.1         
## [28] cli_2.1.0              later_1.1.0.1          htmltools_0.5.0       
## [31] tools_4.0.3            gtable_0.3.0           glue_1.4.2            
## [34] GenomeInfoDbData_1.2.4 fastmatch_1.1-0        Rcpp_1.0.5            
## [37] cellranger_1.1.0       vctrs_0.3.4            polylabelr_0.2.0      
## [40] xfun_0.19              ps_1.4.0               testthat_3.0.0        
## [43] rvest_0.3.6            mime_0.9               lifecycle_0.2.0       
## [46] XML_3.99-0.5           zlibbioc_1.36.0        scales_1.1.1          
## [49] hms_0.5.3              promises_1.1.1         RColorBrewer_1.1-2    
## [52] yaml_2.2.1             memoise_1.1.0          gridExtra_2.3         
## [55] reshape_0.8.8          stringi_1.5.3          RSQLite_2.2.1         
## [58] highr_0.8              genefilter_1.72.0      desc_1.2.0            
## [61] caTools_1.18.0         BiocParallel_1.24.1    rlang_0.4.8           
## [64] pkgconfig_2.0.3        bitops_1.0-6           evaluate_0.14         
## [67] lattice_0.20-41        labeling_0.4.2         htmlwidgets_1.5.2     
## [70] bit_4.0.4              tidyselect_1.1.0       plyr_1.8.6            
## [73] magrittr_1.5           R6_2.5.0               generics_0.1.0        
## [76] DelayedArray_0.16.0    DBI_1.1.0              pillar_1.4.6          
## [79] haven_2.3.1            withr_2.3.0            survival_3.2-7        
## [82] RCurl_1.98-1.2         modelr_0.1.8           crayon_1.3.4          
## [85] KernSmooth_2.23-18     rmarkdown_2.5          locfit_1.5-9.4        
## [88] grid_4.0.3             readxl_1.3.1           data.table_1.13.2     
## [91] blob_1.2.1             reprex_0.3.0           digest_0.6.27         
## [94] xtable_1.8-4           httpuv_1.5.4           munsell_0.5.0

END of report