date generated: 2020-09-10

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

##                   x
## A1BG     -0.3065476
## A1BG-AS1  0.2667380
## A1CF     -0.1889397
## A2M      -0.4487032
## A2M-AS1  -0.9062206
## A2ML1     1.1221162

Here are some metrics about the input data profile:

Profile metrics
Profile metrics
num_genesets 2400
num_genes_in_profile 21631
duplicated_genes_present 0
num_profile_genes_in_sets 8419
num_profile_genes_not_in_sets 13212

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt

Gene sets metrics
Gene sets metrics
num_genesets 2400
num_genesets_excluded 1039
num_genesets_included 1361

Differential pathway expression


Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 100 gene sets

set setSize pANOVA s.dist p.adjustANOVA
Neutrophil degranulation 458 3.16e-61 0.449 4.30e-58
rRNA processing in the nucleus and cytosol 190 7.19e-52 -0.636 4.89e-49
rRNA processing 217 2.08e-51 -0.593 9.44e-49
Major pathway of rRNA processing in the nucleolus and cytosol 180 6.06e-50 -0.641 2.06e-47
Innate Immune System 967 2.26e-44 0.265 6.16e-42
Translation 295 9.42e-40 -0.446 2.14e-37
Metabolism of RNA 685 1.65e-39 -0.294 3.21e-37
Formation of a pool of free 40S subunits 100 4.05e-38 -0.746 6.88e-36
Eukaryotic Translation Elongation 93 1.44e-37 -0.767 2.18e-35
Peptide chain elongation 88 5.06e-36 -0.771 6.88e-34
Selenocysteine synthesis 92 1.36e-35 -0.750 1.68e-33
L13a-mediated translational silencing of Ceruloplasmin expression 110 7.55e-35 -0.678 8.56e-33
GTP hydrolysis and joining of the 60S ribosomal subunit 111 1.11e-34 -0.674 1.16e-32
Eukaryotic Translation Termination 92 3.30e-34 -0.734 3.21e-32
Viral mRNA Translation 88 6.76e-34 -0.747 6.14e-32
Cap-dependent Translation Initiation 118 2.65e-33 -0.640 2.12e-31
Eukaryotic Translation Initiation 118 2.65e-33 -0.640 2.12e-31
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 94 1.58e-32 -0.708 1.20e-30
Response of EIF2AK4 (GCN2) to amino acid deficiency 100 3.17e-31 -0.672 2.27e-29
Influenza Viral RNA Transcription and Replication 135 5.44e-31 -0.576 3.70e-29
Selenoamino acid metabolism 114 2.44e-30 -0.620 1.58e-28
Membrane Trafficking 558 2.21e-28 0.273 1.37e-26
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 114 1.63e-27 -0.588 9.23e-26
Nonsense-Mediated Decay (NMD) 114 1.63e-27 -0.588 9.23e-26
Immune System 1893 2.18e-27 0.150 1.19e-25
Influenza Infection 154 4.36e-27 -0.503 2.28e-25
SRP-dependent cotranslational protein targeting to membrane 111 1.23e-26 -0.586 6.19e-25
Vesicle-mediated transport 648 2.00e-20 0.213 9.72e-19
Signal Transduction 1882 2.53e-19 0.125 1.19e-17
Regulation of expression of SLITs and ROBOs 159 6.82e-17 -0.383 3.09e-15
Formation of the ternary complex, and subsequently, the 43S complex 51 1.92e-16 -0.665 8.41e-15
Metabolism of lipids 625 5.63e-15 0.183 2.40e-13
rRNA modification in the nucleus and cytosol 59 5.93e-15 -0.587 2.45e-13
Gene expression (Transcription) 1326 1.11e-14 -0.126 4.43e-13
Translation initiation complex formation 58 1.23e-14 -0.585 4.80e-13
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 59 2.93e-14 -0.572 1.11e-12
Ribosomal scanning and start codon recognition 58 3.26e-14 -0.576 1.20e-12
Platelet activation, signaling and aggregation 221 1.64e-13 0.288 5.86e-12
Signaling by Receptor Tyrosine Kinases 414 8.43e-13 0.205 2.94e-11
tRNA processing 134 8.34e-12 -0.342 2.83e-10
Signaling by ROBO receptors 199 8.54e-12 -0.281 2.83e-10
Metabolism of amino acids and derivatives 324 9.44e-12 -0.220 3.06e-10
ER to Golgi Anterograde Transport 129 1.91e-11 0.342 6.05e-10
Transport to the Golgi and subsequent modification 155 3.74e-10 0.291 1.16e-08
Hemostasis 548 3.99e-10 0.156 1.21e-08
Asparagine N-linked glycosylation 269 4.67e-10 0.221 1.38e-08
Generic Transcription Pathway 1077 5.38e-10 -0.112 1.56e-08
RNA Polymerase II Transcription 1196 7.42e-10 -0.106 2.10e-08
Signaling by Interleukins 385 7.78e-10 0.183 2.16e-08
Mitochondrial translation elongation 91 8.68e-10 -0.372 2.32e-08
Clathrin-mediated endocytosis 127 8.71e-10 0.315 2.32e-08
Post-translational protein modification 1190 1.08e-09 0.105 2.83e-08
Translocation of ZAP-70 to Immunological synapse 24 1.98e-09 -0.707 5.09e-08
Signaling by Rho GTPases 367 2.45e-09 0.181 6.19e-08
Mitochondrial translation 97 2.66e-09 -0.350 6.59e-08
Activation of the pre-replicative complex 32 2.71e-09 -0.607 6.59e-08
Mitochondrial translation termination 91 3.55e-09 -0.358 8.47e-08
Mitochondrial translation initiation 91 3.68e-09 -0.358 8.63e-08
EPH-Ephrin signaling 79 2.09e-08 0.365 4.82e-07
COPI-mediated anterograde transport 78 2.88e-08 0.363 6.53e-07
RHO GTPases Activate WASPs and WAVEs 35 3.78e-08 0.537 8.44e-07
DNA strand elongation 32 4.60e-08 -0.558 1.01e-06
Rab regulation of trafficking 121 4.86e-08 0.287 1.05e-06
PPARA activates gene expression 104 5.50e-08 0.308 1.17e-06
Metabolism of non-coding RNA 53 6.30e-08 -0.429 1.30e-06
snRNP Assembly 53 6.30e-08 -0.429 1.30e-06
RHO GTPase Effectors 250 7.74e-08 0.197 1.57e-06
Toll-like Receptor Cascades 143 1.03e-07 0.258 2.05e-06
Transport of small molecules 557 1.08e-07 0.132 2.12e-06
Processing of Capped Intron-Containing Pre-mRNA 238 1.29e-07 -0.199 2.51e-06
Regulation of lipid metabolism by PPARalpha 106 1.33e-07 0.296 2.56e-06
Intra-Golgi and retrograde Golgi-to-ER traffic 179 1.62e-07 0.227 3.06e-06
Activation of ATR in response to replication stress 37 2.01e-07 -0.494 3.75e-06
PD-1 signaling 28 2.24e-07 -0.565 4.12e-06
Golgi-to-ER retrograde transport 111 2.50e-07 0.283 4.54e-06
Toll Like Receptor 4 (TLR4) Cascade 121 2.61e-07 0.271 4.67e-06
Generation of second messenger molecules 38 2.64e-07 -0.482 4.67e-06
Response to elevated platelet cytosolic Ca2+ 110 2.85e-07 0.283 4.96e-06
RAB GEFs exchange GTP for GDP on RABs 88 3.07e-07 0.316 5.28e-06
RHO GTPases activate PKNs 48 3.53e-07 0.425 6.00e-06
Diseases of signal transduction by growth factor receptors and second messengers 340 5.72e-07 0.158 9.60e-06
Signaling by NOTCH 182 6.06e-07 0.214 1.01e-05
Telomere C-strand (Lagging Strand) Synthesis 34 6.34e-07 -0.493 1.04e-05
Platelet degranulation 106 7.37e-07 0.278 1.19e-05
Post-translational protein phosphorylation 70 7.43e-07 0.342 1.19e-05
Extension of Telomeres 51 9.09e-07 -0.397 1.44e-05
tRNA processing in the nucleus 59 9.95e-07 -0.368 1.56e-05
COPII-mediated vesicle transport 65 1.07e-06 0.350 1.66e-05
Signaling by NTRKs 116 1.18e-06 0.261 1.81e-05
MyD88:MAL(TIRAP) cascade initiated on plasma membrane 92 1.56e-06 0.290 2.28e-05
Toll Like Receptor 2 (TLR2) Cascade 92 1.56e-06 0.290 2.28e-05
Toll Like Receptor TLR1:TLR2 Cascade 92 1.56e-06 0.290 2.28e-05
Toll Like Receptor TLR6:TLR2 Cascade 92 1.56e-06 0.290 2.28e-05
Cargo recognition for clathrin-mediated endocytosis 90 2.04e-06 0.290 2.95e-05
IRAK4 deficiency (TLR2/4) 10 2.19e-06 0.864 3.11e-05
MyD88 deficiency (TLR2/4) 10 2.19e-06 0.864 3.11e-05
trans-Golgi Network Vesicle Budding 69 3.01e-06 0.325 4.22e-05
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 81 3.26e-06 0.299 4.53e-05
EPHB-mediated forward signaling 32 4.14e-06 0.470 5.69e-05
tRNA modification in the nucleus and cytosol 43 5.03e-06 -0.402 6.85e-05


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pANOVA s.dist p.adjustANOVA
Neutrophil degranulation 458 3.16e-61 0.449000 4.30e-58
rRNA processing in the nucleus and cytosol 190 7.19e-52 -0.636000 4.89e-49
rRNA processing 217 2.08e-51 -0.593000 9.44e-49
Major pathway of rRNA processing in the nucleolus and cytosol 180 6.06e-50 -0.641000 2.06e-47
Innate Immune System 967 2.26e-44 0.265000 6.16e-42
Translation 295 9.42e-40 -0.446000 2.14e-37
Metabolism of RNA 685 1.65e-39 -0.294000 3.21e-37
Formation of a pool of free 40S subunits 100 4.05e-38 -0.746000 6.88e-36
Eukaryotic Translation Elongation 93 1.44e-37 -0.767000 2.18e-35
Peptide chain elongation 88 5.06e-36 -0.771000 6.88e-34
Selenocysteine synthesis 92 1.36e-35 -0.750000 1.68e-33
L13a-mediated translational silencing of Ceruloplasmin expression 110 7.55e-35 -0.678000 8.56e-33
GTP hydrolysis and joining of the 60S ribosomal subunit 111 1.11e-34 -0.674000 1.16e-32
Eukaryotic Translation Termination 92 3.30e-34 -0.734000 3.21e-32
Viral mRNA Translation 88 6.76e-34 -0.747000 6.14e-32
Cap-dependent Translation Initiation 118 2.65e-33 -0.640000 2.12e-31
Eukaryotic Translation Initiation 118 2.65e-33 -0.640000 2.12e-31
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 94 1.58e-32 -0.708000 1.20e-30
Response of EIF2AK4 (GCN2) to amino acid deficiency 100 3.17e-31 -0.672000 2.27e-29
Influenza Viral RNA Transcription and Replication 135 5.44e-31 -0.576000 3.70e-29
Selenoamino acid metabolism 114 2.44e-30 -0.620000 1.58e-28
Membrane Trafficking 558 2.21e-28 0.273000 1.37e-26
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 114 1.63e-27 -0.588000 9.23e-26
Nonsense-Mediated Decay (NMD) 114 1.63e-27 -0.588000 9.23e-26
Immune System 1893 2.18e-27 0.150000 1.19e-25
Influenza Infection 154 4.36e-27 -0.503000 2.28e-25
SRP-dependent cotranslational protein targeting to membrane 111 1.23e-26 -0.586000 6.19e-25
Vesicle-mediated transport 648 2.00e-20 0.213000 9.72e-19
Signal Transduction 1882 2.53e-19 0.125000 1.19e-17
Regulation of expression of SLITs and ROBOs 159 6.82e-17 -0.383000 3.09e-15
Formation of the ternary complex, and subsequently, the 43S complex 51 1.92e-16 -0.665000 8.41e-15
Metabolism of lipids 625 5.63e-15 0.183000 2.40e-13
rRNA modification in the nucleus and cytosol 59 5.93e-15 -0.587000 2.45e-13
Gene expression (Transcription) 1326 1.11e-14 -0.126000 4.43e-13
Translation initiation complex formation 58 1.23e-14 -0.585000 4.80e-13
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 59 2.93e-14 -0.572000 1.11e-12
Ribosomal scanning and start codon recognition 58 3.26e-14 -0.576000 1.20e-12
Platelet activation, signaling and aggregation 221 1.64e-13 0.288000 5.86e-12
Signaling by Receptor Tyrosine Kinases 414 8.43e-13 0.205000 2.94e-11
tRNA processing 134 8.34e-12 -0.342000 2.83e-10
Signaling by ROBO receptors 199 8.54e-12 -0.281000 2.83e-10
Metabolism of amino acids and derivatives 324 9.44e-12 -0.220000 3.06e-10
ER to Golgi Anterograde Transport 129 1.91e-11 0.342000 6.05e-10
Transport to the Golgi and subsequent modification 155 3.74e-10 0.291000 1.16e-08
Hemostasis 548 3.99e-10 0.156000 1.21e-08
Asparagine N-linked glycosylation 269 4.67e-10 0.221000 1.38e-08
Generic Transcription Pathway 1077 5.38e-10 -0.112000 1.56e-08
RNA Polymerase II Transcription 1196 7.42e-10 -0.106000 2.10e-08
Signaling by Interleukins 385 7.78e-10 0.183000 2.16e-08
Mitochondrial translation elongation 91 8.68e-10 -0.372000 2.32e-08
Clathrin-mediated endocytosis 127 8.71e-10 0.315000 2.32e-08
Post-translational protein modification 1190 1.08e-09 0.105000 2.83e-08
Translocation of ZAP-70 to Immunological synapse 24 1.98e-09 -0.707000 5.09e-08
Signaling by Rho GTPases 367 2.45e-09 0.181000 6.19e-08
Mitochondrial translation 97 2.66e-09 -0.350000 6.59e-08
Activation of the pre-replicative complex 32 2.71e-09 -0.607000 6.59e-08
Mitochondrial translation termination 91 3.55e-09 -0.358000 8.47e-08
Mitochondrial translation initiation 91 3.68e-09 -0.358000 8.63e-08
EPH-Ephrin signaling 79 2.09e-08 0.365000 4.82e-07
COPI-mediated anterograde transport 78 2.88e-08 0.363000 6.53e-07
RHO GTPases Activate WASPs and WAVEs 35 3.78e-08 0.537000 8.44e-07
DNA strand elongation 32 4.60e-08 -0.558000 1.01e-06
Rab regulation of trafficking 121 4.86e-08 0.287000 1.05e-06
PPARA activates gene expression 104 5.50e-08 0.308000 1.17e-06
Metabolism of non-coding RNA 53 6.30e-08 -0.429000 1.30e-06
snRNP Assembly 53 6.30e-08 -0.429000 1.30e-06
RHO GTPase Effectors 250 7.74e-08 0.197000 1.57e-06
Toll-like Receptor Cascades 143 1.03e-07 0.258000 2.05e-06
Transport of small molecules 557 1.08e-07 0.132000 2.12e-06
Processing of Capped Intron-Containing Pre-mRNA 238 1.29e-07 -0.199000 2.51e-06
Regulation of lipid metabolism by PPARalpha 106 1.33e-07 0.296000 2.56e-06
Intra-Golgi and retrograde Golgi-to-ER traffic 179 1.62e-07 0.227000 3.06e-06
Activation of ATR in response to replication stress 37 2.01e-07 -0.494000 3.75e-06
PD-1 signaling 28 2.24e-07 -0.565000 4.12e-06
Golgi-to-ER retrograde transport 111 2.50e-07 0.283000 4.54e-06
Toll Like Receptor 4 (TLR4) Cascade 121 2.61e-07 0.271000 4.67e-06
Generation of second messenger molecules 38 2.64e-07 -0.482000 4.67e-06
Response to elevated platelet cytosolic Ca2+ 110 2.85e-07 0.283000 4.96e-06
RAB GEFs exchange GTP for GDP on RABs 88 3.07e-07 0.316000 5.28e-06
RHO GTPases activate PKNs 48 3.53e-07 0.425000 6.00e-06
Diseases of signal transduction by growth factor receptors and second messengers 340 5.72e-07 0.158000 9.60e-06
Signaling by NOTCH 182 6.06e-07 0.214000 1.01e-05
Telomere C-strand (Lagging Strand) Synthesis 34 6.34e-07 -0.493000 1.04e-05
Platelet degranulation 106 7.37e-07 0.278000 1.19e-05
Post-translational protein phosphorylation 70 7.43e-07 0.342000 1.19e-05
Extension of Telomeres 51 9.09e-07 -0.397000 1.44e-05
tRNA processing in the nucleus 59 9.95e-07 -0.368000 1.56e-05
COPII-mediated vesicle transport 65 1.07e-06 0.350000 1.66e-05
Signaling by NTRKs 116 1.18e-06 0.261000 1.81e-05
MyD88:MAL(TIRAP) cascade initiated on plasma membrane 92 1.56e-06 0.290000 2.28e-05
Toll Like Receptor 2 (TLR2) Cascade 92 1.56e-06 0.290000 2.28e-05
Toll Like Receptor TLR1:TLR2 Cascade 92 1.56e-06 0.290000 2.28e-05
Toll Like Receptor TLR6:TLR2 Cascade 92 1.56e-06 0.290000 2.28e-05
Cargo recognition for clathrin-mediated endocytosis 90 2.04e-06 0.290000 2.95e-05
IRAK4 deficiency (TLR2/4) 10 2.19e-06 0.864000 3.11e-05
MyD88 deficiency (TLR2/4) 10 2.19e-06 0.864000 3.11e-05
trans-Golgi Network Vesicle Budding 69 3.01e-06 0.325000 4.22e-05
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 81 3.26e-06 0.299000 4.53e-05
EPHB-mediated forward signaling 32 4.14e-06 0.470000 5.69e-05
tRNA modification in the nucleus and cytosol 43 5.03e-06 -0.402000 6.85e-05
COPI-independent Golgi-to-ER retrograde traffic 33 5.41e-06 0.457000 7.29e-05
RHO GTPases Activate ROCKs 18 6.30e-06 0.615000 8.41e-05
Antigen processing-Cross presentation 97 6.61e-06 0.265000 8.74e-05
Signaling by NTRK1 (TRKA) 101 7.13e-06 0.258000 9.33e-05
Phosphorylation of CD3 and TCR zeta chains 27 1.07e-05 -0.489000 1.38e-04
Pre-NOTCH Expression and Processing 65 1.10e-05 0.315000 1.41e-04
Regulation of cholesterol biosynthesis by SREBP (SREBF) 55 1.17e-05 0.342000 1.47e-04
Resolution of AP sites via the multiple-nucleotide patch replacement pathway 24 1.17e-05 -0.517000 1.47e-04
L1CAM interactions 85 1.25e-05 0.274000 1.56e-04
Metabolism of steroids 119 1.42e-05 0.230000 1.76e-04
Phospholipid metabolism 186 1.46e-05 0.184000 1.79e-04
Cargo concentration in the ER 30 1.48e-05 0.457000 1.79e-04
GPVI-mediated activation cascade 31 1.49e-05 0.449000 1.79e-04
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism 12 1.52e-05 0.721000 1.79e-04
alpha-linolenic acid (ALA) metabolism 12 1.52e-05 0.721000 1.79e-04
Signaling by GPCR 536 1.59e-05 0.109000 1.86e-04
mRNA Splicing 187 1.64e-05 -0.183000 1.90e-04
Interleukin-1 family signaling 124 1.75e-05 0.223000 2.02e-04
mRNA Splicing - Major Pathway 179 2.01e-05 -0.185000 2.30e-04
Lagging Strand Synthesis 20 2.12e-05 -0.549000 2.41e-04
tRNA Aminoacylation 42 2.27e-05 -0.378000 2.56e-04
VEGFA-VEGFR2 Pathway 92 2.49e-05 0.254000 2.77e-04
Detoxification of Reactive Oxygen Species 32 2.51e-05 0.430000 2.77e-04
PCNA-Dependent Long Patch Base Excision Repair 21 2.52e-05 -0.531000 2.77e-04
Degradation of the extracellular matrix 78 3.14e-05 0.273000 3.42e-04
Interactions of Vpr with host cellular proteins 37 3.43e-05 -0.394000 3.70e-04
Mitochondrial protein import 64 3.50e-05 -0.299000 3.75e-04
Integration of energy metabolism 86 3.88e-05 0.257000 4.10e-04
MyD88 dependent cascade initiated on endosome 89 3.92e-05 0.252000 4.10e-04
Toll Like Receptor 7/8 (TLR7/8) Cascade 89 3.92e-05 0.252000 4.10e-04
RNA Polymerase I Transcription Initiation 47 3.98e-05 -0.346000 4.14e-04
Resolution of Abasic Sites (AP sites) 37 4.22e-05 -0.389000 4.35e-04
Interleukin-1 signaling 97 4.38e-05 0.240000 4.46e-04
RAB geranylgeranylation 60 4.39e-05 0.305000 4.46e-04
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 88 4.58e-05 0.251000 4.62e-04
Signaling by WNT 253 4.93e-05 0.148000 4.94e-04
Chromosome Maintenance 105 5.30e-05 -0.228000 5.26e-04
Transcriptional regulation of white adipocyte differentiation 77 5.40e-05 0.266000 5.33e-04
MAP2K and MAPK activation 34 5.66e-05 0.399000 5.54e-04
Interactions of Rev with host cellular proteins 37 6.52e-05 -0.379000 6.34e-04
CD22 mediated BCR regulation 59 7.14e-05 -0.299000 6.89e-04
Rev-mediated nuclear export of HIV RNA 35 7.89e-05 -0.386000 7.55e-04
Diseases associated with the TLR signaling cascade 23 7.99e-05 0.475000 7.55e-04
Diseases of Immune System 23 7.99e-05 0.475000 7.55e-04
Interleukin-3, Interleukin-5 and GM-CSF signaling 40 8.08e-05 0.360000 7.58e-04
Toll Like Receptor 9 (TLR9) Cascade 93 8.40e-05 0.236000 7.83e-04
Signaling by VEGF 100 8.60e-05 0.227000 7.96e-04
Signaling by MET 61 1.02e-04 0.288000 9.39e-04
Platelet sensitization by LDL 16 1.04e-04 0.560000 9.47e-04
Signal transduction by L1 20 1.05e-04 0.501000 9.53e-04
BBSome-mediated cargo-targeting to cilium 22 1.14e-04 -0.475000 1.02e-03
Signaling by Erythropoietin 24 1.26e-04 0.452000 1.13e-03
Class I MHC mediated antigen processing & presentation 349 1.35e-04 0.119000 1.19e-03
Intraflagellar transport 39 1.35e-04 -0.353000 1.19e-03
GPCR downstream signalling 494 1.40e-04 0.100000 1.23e-03
Sema4D in semaphorin signaling 22 1.52e-04 0.466000 1.32e-03
Semaphorin interactions 57 1.53e-04 0.290000 1.32e-03
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 11 1.55e-04 0.659000 1.33e-03
Vpr-mediated nuclear import of PICs 34 1.62e-04 -0.374000 1.38e-03
Pre-NOTCH Transcription and Translation 49 1.82e-04 0.309000 1.55e-03
Golgi Associated Vesicle Biogenesis 55 1.83e-04 0.292000 1.55e-03
TBC/RABGAPs 45 1.90e-04 0.322000 1.59e-03
Processive synthesis on the lagging strand 15 2.00e-04 -0.555000 1.67e-03
Signaling by high-kinase activity BRAF mutants 31 2.02e-04 0.386000 1.68e-03
RHO GTPases Activate NADPH Oxidases 21 2.04e-04 0.468000 1.68e-03
MyD88-independent TLR4 cascade 96 2.10e-04 0.219000 1.72e-03
TRIF(TICAM1)-mediated TLR4 signaling 96 2.10e-04 0.219000 1.72e-03
S Phase 160 2.31e-04 -0.169000 1.88e-03
Regulation of TLR by endogenous ligand 11 2.34e-04 0.641000 1.88e-03
Neuronal System 258 2.50e-04 0.132000 2.00e-03
Transport of Mature mRNA derived from an Intron-Containing Transcript 72 2.57e-04 -0.249000 2.03e-03
Recycling pathway of L1 26 2.57e-04 0.414000 2.03e-03
Metabolism of carbohydrates 244 2.62e-04 0.136000 2.05e-03
Signaling by RAF1 mutants 34 2.62e-04 0.362000 2.05e-03
Oncogenic MAPK signaling 73 2.75e-04 0.246000 2.14e-03
Activation of gene expression by SREBF (SREBP) 42 2.86e-04 0.323000 2.21e-03
Nucleobase biosynthesis 13 2.88e-04 -0.581000 2.22e-03
Polymerase switching on the C-strand of the telomere 26 2.94e-04 -0.410000 2.25e-03
Programmed Cell Death 169 3.05e-04 0.161000 2.32e-03
RHO GTPases activate CIT 18 3.25e-04 0.489000 2.45e-03
Metabolism 1768 3.32e-04 0.051400 2.50e-03
Cytokine Signaling in Immune system 735 3.43e-04 0.077600 2.56e-03
Nuclear import of Rev protein 34 3.66e-04 -0.353000 2.72e-03
Extracellular matrix organization 219 3.70e-04 0.140000 2.74e-03
Classical antibody-mediated complement activation 69 3.73e-04 -0.248000 2.74e-03
G-protein beta:gamma signalling 29 3.86e-04 0.381000 2.79e-03
MyD88 cascade initiated on plasma membrane 82 3.87e-04 0.227000 2.79e-03
Toll Like Receptor 10 (TLR10) Cascade 82 3.87e-04 0.227000 2.79e-03
Toll Like Receptor 5 (TLR5) Cascade 82 3.87e-04 0.227000 2.79e-03
Rho GTPase cycle 126 4.00e-04 0.183000 2.87e-03
ROS and RNS production in phagocytes 31 4.06e-04 0.367000 2.89e-03
Pre-NOTCH Processing in Golgi 18 4.08e-04 0.481000 2.89e-03
Collagen degradation 29 4.12e-04 0.379000 2.90e-03
Apoptosis 166 4.19e-04 0.159000 2.94e-03
DNA Repair 289 4.35e-04 -0.120000 3.04e-03
FCGR activation 76 4.56e-04 -0.233000 3.17e-03
Intracellular signaling by second messengers 271 4.61e-04 0.124000 3.18e-03
Smooth Muscle Contraction 31 4.74e-04 0.363000 3.25e-03
Endosomal Sorting Complex Required For Transport (ESCRT) 29 4.77e-04 0.375000 3.25e-03
NEP/NS2 Interacts with the Cellular Export Machinery 32 4.77e-04 -0.357000 3.25e-03
Signaling by BRAF and RAF fusions 57 4.86e-04 0.267000 3.29e-03
Muscle contraction 141 4.92e-04 0.170000 3.31e-03
Ion channel transport 133 5.22e-04 0.174000 3.50e-03
RHO GTPases activate PAKs 20 5.38e-04 0.447000 3.59e-03
ER-Phagosome pathway 82 5.52e-04 0.221000 3.66e-03
Scavenging of heme from plasma 71 5.61e-04 -0.237000 3.69e-03
Creation of C4 and C2 activators 71 5.62e-04 -0.237000 3.69e-03
Hyaluronan uptake and degradation 12 5.72e-04 0.574000 3.74e-03
Sema4D induced cell migration and growth-cone collapse 19 5.82e-04 0.456000 3.79e-03
Unwinding of DNA 12 5.97e-04 -0.572000 3.87e-03
Transport of Mature Transcript to Cytoplasm 81 6.35e-04 -0.220000 4.06e-03
Removal of the Flap Intermediate 14 6.35e-04 -0.527000 4.06e-03
Platelet homeostasis 69 6.38e-04 0.238000 4.06e-03
Gap junction trafficking 13 6.40e-04 0.547000 4.06e-03
VLDLR internalisation and degradation 12 6.42e-04 0.569000 4.06e-03
Opioid Signalling 75 6.72e-04 0.227000 4.22e-03
Paradoxical activation of RAF signaling by kinase inactive BRAF 38 6.83e-04 0.318000 4.22e-03
Signaling by RAS mutants 38 6.83e-04 0.318000 4.22e-03
Signaling by moderate kinase activity BRAF mutants 38 6.83e-04 0.318000 4.22e-03
Signaling downstream of RAS mutants 38 6.83e-04 0.318000 4.22e-03
Postmitotic nuclear pore complex (NPC) reformation 27 6.85e-04 -0.377000 4.22e-03
Cilium Assembly 181 6.95e-04 -0.146000 4.24e-03
Recognition of DNA damage by PCNA-containing replication complex 30 6.95e-04 -0.358000 4.24e-03
Sphingolipid metabolism 77 7.38e-04 0.222000 4.49e-03
Synthesis of DNA 118 7.45e-04 -0.180000 4.51e-03
Uptake and function of anthrax toxins 10 8.17e-04 0.611000 4.92e-03
Cellular response to hypoxia 71 8.35e-04 0.229000 5.01e-03
Synthesis of Leukotrienes (LT) and Eoxins (EX) 15 8.51e-04 0.497000 5.08e-03
Dual Incision in GG-NER 41 8.66e-04 -0.301000 5.14e-03
Plasma lipoprotein assembly, remodeling, and clearance 53 8.83e-04 0.264000 5.21e-03
Transmission across Chemical Synapses 172 8.85e-04 0.147000 5.21e-03
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 13 9.51e-04 0.529000 5.58e-03
Gap-filling DNA repair synthesis and ligation in GG-NER 25 9.91e-04 -0.380000 5.79e-03
MET activates RAP1 and RAC1 10 1.02e-03 0.600000 5.89e-03
Amyloid fiber formation 51 1.02e-03 0.266000 5.89e-03
SUMOylation of DNA damage response and repair proteins 77 1.05e-03 -0.216000 6.05e-03
Transport of the SLBP Dependant Mature mRNA 36 1.09e-03 -0.315000 6.22e-03
Termination of translesion DNA synthesis 32 1.09e-03 -0.334000 6.22e-03
HDR through Homologous Recombination (HRR) 66 1.12e-03 -0.232000 6.36e-03
PIP3 activates AKT signaling 239 1.12e-03 0.122000 6.36e-03
Sealing of the nuclear envelope (NE) by ESCRT-III 25 1.13e-03 0.376000 6.37e-03
Homologous DNA Pairing and Strand Exchange 42 1.16e-03 -0.290000 6.52e-03
Budding and maturation of HIV virion 26 1.18e-03 0.367000 6.60e-03
WNT5A-dependent internalization of FZD4 13 1.18e-03 0.519000 6.60e-03
RNA Polymerase I Transcription Termination 30 1.23e-03 -0.341000 6.81e-03
Transferrin endocytosis and recycling 26 1.25e-03 0.365000 6.94e-03
Deubiquitination 241 1.27e-03 0.121000 6.99e-03
Advanced glycosylation endproduct receptor signaling 12 1.28e-03 0.537000 7.01e-03
Transport of the SLBP independent Mature mRNA 35 1.28e-03 -0.314000 7.01e-03
Glycerophospholipid biosynthesis 107 1.29e-03 0.180000 7.01e-03
Integrin signaling 22 1.34e-03 0.395000 7.29e-03
MHC class II antigen presentation 101 1.39e-03 0.184000 7.46e-03
Export of Viral Ribonucleoproteins from Nucleus 33 1.39e-03 -0.322000 7.46e-03
COPI-dependent Golgi-to-ER retrograde traffic 78 1.44e-03 0.209000 7.73e-03
NS1 Mediated Effects on Host Pathways 40 1.45e-03 -0.291000 7.73e-03
Insulin receptor recycling 21 1.49e-03 0.400000 7.93e-03
DNA Replication 125 1.50e-03 -0.164000 7.95e-03
Prolonged ERK activation events 13 1.51e-03 0.508000 7.99e-03
XBP1(S) activates chaperone genes 47 1.53e-03 0.267000 8.06e-03
Translocation of SLC2A4 (GLUT4) to the plasma membrane 48 1.54e-03 0.264000 8.06e-03
SUMOylation of RNA binding proteins 47 1.56e-03 -0.267000 8.14e-03
FCERI mediated Ca+2 mobilization 89 1.57e-03 -0.194000 8.15e-03
Erythrocytes take up carbon dioxide and release oxygen 12 1.58e-03 0.527000 8.15e-03
O2/CO2 exchange in erythrocytes 12 1.58e-03 0.527000 8.15e-03
SARS-CoV Infections 83 1.69e-03 0.199000 8.68e-03
Transcriptional regulation of granulopoiesis 46 1.73e-03 0.267000 8.87e-03
NOTCH4 Activation and Transmission of Signal to the Nucleus 10 1.74e-03 0.572000 8.87e-03
Notch-HLH transcription pathway 28 1.79e-03 0.341000 9.07e-03
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 11 1.79e-03 0.544000 9.07e-03
Erythropoietin activates RAS 13 1.81e-03 0.500000 9.12e-03
IRE1alpha activates chaperones 49 1.82e-03 0.257000 9.13e-03
Platelet Aggregation (Plug Formation) 28 1.83e-03 0.340000 9.18e-03
RAF activation 32 1.97e-03 0.316000 9.83e-03
SUMOylation of chromatin organization proteins 57 2.03e-03 -0.236000 1.01e-02
Golgi Cisternae Pericentriolar Stack Reorganization 14 2.08e-03 0.475000 1.03e-02
Autophagy 124 2.10e-03 0.160000 1.03e-02
Neurotransmitter receptors and postsynaptic signal transmission 123 2.10e-03 0.161000 1.03e-02
Costimulation by the CD28 family 74 2.14e-03 -0.206000 1.05e-02
Retrograde neurotrophin signalling 12 2.17e-03 0.511000 1.06e-02
G1/S Transition 130 2.21e-03 -0.155000 1.07e-02
Translesion synthesis by REV1 16 2.21e-03 -0.442000 1.07e-02
RNA Polymerase I Promoter Opening 19 2.22e-03 0.405000 1.07e-02
Cell Cycle 624 2.23e-03 -0.071700 1.07e-02
Fanconi Anemia Pathway 36 2.26e-03 -0.294000 1.08e-02
Signaling by NOTCH4 78 2.27e-03 0.200000 1.08e-02
Presynaptic phase of homologous DNA pairing and strand exchange 39 2.28e-03 -0.282000 1.08e-02
Toll Like Receptor 3 (TLR3) Cascade 92 2.29e-03 0.184000 1.08e-02
Cytosolic tRNA aminoacylation 24 2.30e-03 -0.359000 1.09e-02
Transport of Ribonucleoproteins into the Host Nucleus 32 2.36e-03 -0.311000 1.11e-02
Role of phospholipids in phagocytosis 88 2.40e-03 -0.187000 1.13e-02
Initial triggering of complement 78 2.43e-03 -0.199000 1.14e-02
Lysosome Vesicle Biogenesis 32 2.44e-03 0.310000 1.14e-02
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 21 2.48e-03 0.381000 1.15e-02
Neurodegenerative Diseases 21 2.48e-03 0.381000 1.15e-02
Glycosphingolipid metabolism 36 2.50e-03 0.291000 1.15e-02
Signalling to ERKs 32 2.54e-03 0.308000 1.17e-02
Glycosaminoglycan metabolism 94 2.57e-03 0.180000 1.18e-02
Negative regulation of MET activity 18 2.58e-03 0.410000 1.18e-02
BMAL1:CLOCK,NPAS2 activates circadian gene expression 25 2.61e-03 0.348000 1.19e-02
GABA receptor activation 35 2.73e-03 0.293000 1.24e-02
Hyaluronan metabolism 15 2.74e-03 0.447000 1.24e-02
Mitochondrial tRNA aminoacylation 21 2.83e-03 -0.376000 1.27e-02
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 22 2.99e-03 0.366000 1.34e-02
HDMs demethylate histones 22 3.02e-03 0.365000 1.35e-02
Regulation of signaling by CBL 18 3.09e-03 0.403000 1.38e-02
PCP/CE pathway 86 3.24e-03 0.184000 1.44e-02
Beta-catenin independent WNT signaling 136 3.27e-03 0.146000 1.45e-02
Leading Strand Synthesis 14 3.29e-03 -0.454000 1.45e-02
Polymerase switching 14 3.29e-03 -0.454000 1.45e-02
Translesion synthesis by POLI 17 3.35e-03 -0.411000 1.47e-02
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 182 3.37e-03 -0.126000 1.47e-02
Amino acids regulate mTORC1 50 3.38e-03 0.240000 1.47e-02
Telomere Maintenance 80 3.48e-03 -0.189000 1.51e-02
TCF dependent signaling in response to WNT 165 3.49e-03 0.132000 1.51e-02
VxPx cargo-targeting to cilium 19 3.50e-03 0.387000 1.51e-02
Telomere C-strand synthesis initiation 13 3.50e-03 -0.468000 1.51e-02
Role of LAT2/NTAL/LAB on calcium mobilization 74 3.66e-03 -0.195000 1.57e-02
RORA activates gene expression 18 3.76e-03 0.394000 1.61e-02
EPH-ephrin mediated repulsion of cells 40 3.78e-03 0.265000 1.61e-02
Regulation of insulin secretion 60 3.85e-03 0.216000 1.64e-02
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 11 3.87e-03 -0.503000 1.64e-02
Transport of Mature mRNAs Derived from Intronless Transcripts 43 3.88e-03 -0.255000 1.64e-02
Intra-Golgi traffic 43 4.02e-03 0.253000 1.70e-02
SUMOylation of SUMOylation proteins 35 4.04e-03 -0.281000 1.70e-02
Processive synthesis on the C-strand of the telomere 19 4.06e-03 -0.381000 1.70e-02
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 84 4.09e-03 -0.181000 1.71e-02
Energy dependent regulation of mTOR by LKB1-AMPK 27 4.14e-03 0.319000 1.72e-02
Signal amplification 28 4.16e-03 0.313000 1.72e-02
Organelle biogenesis and maintenance 269 4.21e-03 -0.101000 1.74e-02
SLBP independent Processing of Histone Pre-mRNAs 10 4.33e-03 -0.521000 1.78e-02
Gap junction trafficking and regulation 15 4.41e-03 0.425000 1.81e-02
MAP kinase activation 63 4.44e-03 0.207000 1.82e-02
Transport of Mature mRNA Derived from an Intronless Transcript 42 4.56e-03 -0.253000 1.87e-02
Transcriptional Regulation by E2F6 34 4.63e-03 -0.281000 1.89e-02
AKT phosphorylates targets in the cytosol 14 4.65e-03 0.437000 1.89e-02
Regulation of HSF1-mediated heat shock response 79 4.76e-03 -0.184000 1.93e-02
RNA Polymerase III Transcription Initiation From Type 1 Promoter 28 4.96e-03 -0.307000 2.00e-02
Global Genome Nucleotide Excision Repair (GG-NER) 84 5.21e-03 -0.176000 2.10e-02
Purine ribonucleoside monophosphate biosynthesis 10 5.45e-03 -0.507000 2.19e-02
Cellular response to heat stress 93 5.53e-03 -0.166000 2.22e-02
Transcription-Coupled Nucleotide Excision Repair (TC-NER) 78 5.57e-03 -0.182000 2.22e-02
PI Metabolism 80 5.58e-03 0.179000 2.22e-02
Thrombin signalling through proteinase activated receptors (PARs) 27 5.61e-03 0.308000 2.23e-02
Transport of bile salts and organic acids, metal ions and amine compounds 55 5.70e-03 0.215000 2.25e-02
Translesion synthesis by POLK 17 5.73e-03 -0.387000 2.26e-02
Nuclear Events (kinase and transcription factor activation) 53 5.86e-03 0.219000 2.31e-02
Growth hormone receptor signaling 20 5.93e-03 0.355000 2.32e-02
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 32 6.07e-03 -0.280000 2.37e-02
Regulation of Glucokinase by Glucokinase Regulatory Protein 32 6.07e-03 -0.280000 2.37e-02
Regulation of PTEN stability and activity 66 6.11e-03 0.195000 2.38e-02
Regulation of IFNG signaling 14 6.27e-03 0.422000 2.43e-02
Gap-filling DNA repair synthesis and ligation in TC-NER 64 6.34e-03 -0.197000 2.45e-02
Activation of GABAB receptors 30 6.39e-03 0.288000 2.46e-02
GABA B receptor activation 30 6.39e-03 0.288000 2.46e-02
Signaling by NOTCH1 66 6.51e-03 0.194000 2.50e-02
Interleukin-17 signaling 68 6.57e-03 0.191000 2.51e-02
Nucleotide Excision Repair 110 6.75e-03 -0.150000 2.57e-02
HDACs deacetylate histones 47 6.77e-03 0.228000 2.57e-02
RHO GTPases activate IQGAPs 11 6.80e-03 0.471000 2.58e-02
Signaling by Nuclear Receptors 218 6.89e-03 0.106000 2.61e-02
Signaling by Insulin receptor 59 6.91e-03 0.203000 2.61e-02
RUNX1 regulates transcription of genes involved in differentiation of HSCs 82 6.97e-03 0.172000 2.62e-02
Signaling by SCF-KIT 40 7.14e-03 0.246000 2.68e-02
Factors involved in megakaryocyte development and platelet production 116 7.17e-03 0.145000 2.68e-02
C-type lectin receptors (CLRs) 128 7.55e-03 0.137000 2.81e-02
Deadenylation-dependent mRNA decay 53 7.56e-03 -0.212000 2.81e-02
mRNA decay by 3' to 5' exoribonuclease 16 7.70e-03 -0.385000 2.86e-02
Dual incision in TC-NER 65 7.74e-03 -0.191000 2.86e-02
DNA Damage Bypass 47 7.76e-03 -0.224000 2.86e-02
Late endosomal microautophagy 30 7.81e-03 0.281000 2.87e-02
Synthesis of PIPs at the plasma membrane 52 7.99e-03 0.213000 2.93e-02
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 64 8.16e-03 0.191000 2.99e-02
G beta:gamma signalling through PI3Kgamma 22 8.21e-03 0.326000 3.00e-02
Trafficking of GluR2-containing AMPA receptors 12 8.28e-03 0.440000 3.01e-02
RNA Polymerase II Transcription Termination 65 8.32e-03 -0.189000 3.02e-02
Cellular Senescence 144 8.71e-03 0.127000 3.15e-02
Synthesis of PC 24 8.72e-03 0.309000 3.15e-02
Heme degradation 10 8.89e-03 0.478000 3.20e-02
Beta-catenin phosphorylation cascade 17 9.56e-03 0.363000 3.43e-02
EGFR downregulation 27 9.76e-03 0.287000 3.49e-02
ADP signalling through P2Y purinoceptor 1 21 9.78e-03 0.326000 3.49e-02
Leishmania infection 245 1.01e-02 0.095500 3.58e-02
Oxidative Stress Induced Senescence 79 1.01e-02 0.167000 3.59e-02
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 11 1.02e-02 0.447000 3.63e-02
activated TAK1 mediates p38 MAPK activation 19 1.03e-02 0.340000 3.65e-02
RNA Polymerase III Transcription Initiation From Type 2 Promoter 27 1.04e-02 -0.285000 3.68e-02
mRNA Splicing - Minor Pathway 52 1.05e-02 -0.205000 3.69e-02
Frs2-mediated activation 11 1.05e-02 0.445000 3.69e-02
Signaling by NOTCH3 42 1.05e-02 0.228000 3.69e-02
G alpha (s) signalling events 141 1.07e-02 0.124000 3.74e-02
Regulated proteolysis of p75NTR 11 1.09e-02 0.443000 3.78e-02
Fatty acid metabolism 152 1.09e-02 0.120000 3.78e-02
Diseases of programmed cell death 23 1.09e-02 0.307000 3.78e-02
Disease 1299 1.13e-02 0.041900 3.89e-02
Spry regulation of FGF signaling 16 1.13e-02 0.366000 3.90e-02
HDR through Single Strand Annealing (SSA) 37 1.16e-02 -0.240000 3.97e-02
rRNA processing in the mitochondrion 27 1.17e-02 -0.280000 4.00e-02
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 33 1.17e-02 0.253000 4.00e-02
ERKs are inactivated 13 1.17e-02 0.404000 4.00e-02
Nuclear Pore Complex (NPC) Disassembly 36 1.18e-02 -0.242000 4.02e-02
G1/S-Specific Transcription 29 1.20e-02 -0.269000 4.07e-02
Mucopolysaccharidoses 11 1.22e-02 0.437000 4.12e-02
Caspase activation via extrinsic apoptotic signalling pathway 25 1.26e-02 0.288000 4.24e-02
Viral Messenger RNA Synthesis 44 1.26e-02 -0.217000 4.25e-02
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 14 1.27e-02 -0.385000 4.25e-02
Apoptotic execution phase 45 1.29e-02 0.214000 4.33e-02
Interleukin-4 and Interleukin-13 signaling 92 1.30e-02 0.150000 4.33e-02
PTEN Regulation 138 1.30e-02 0.122000 4.34e-02
LDL clearance 18 1.31e-02 0.338000 4.36e-02
FCGR3A-mediated IL10 synthesis 99 1.34e-02 -0.144000 4.45e-02
Collagen formation 66 1.36e-02 0.176000 4.50e-02
DNA methylation 20 1.37e-02 0.318000 4.53e-02
MTOR signalling 38 1.39e-02 0.231000 4.58e-02
G alpha (12/13) signalling events 69 1.46e-02 0.170000 4.79e-02
ESR-mediated signaling 162 1.46e-02 0.111000 4.80e-02
FOXO-mediated transcription of cell death genes 16 1.50e-02 0.351000 4.91e-02
Dissolution of Fibrin Clot 12 1.51e-02 0.405000 4.93e-02
FLT3 Signaling 244 1.52e-02 0.090200 4.96e-02
TNFs bind their physiological receptors 25 1.53e-02 -0.280000 4.98e-02
NR1H2 and NR1H3-mediated signaling 39 1.54e-02 0.224000 5.00e-02
MAPK family signaling cascades 269 1.56e-02 0.085700 5.03e-02
Removal of the Flap Intermediate from the C-strand 17 1.56e-02 -0.339000 5.03e-02
Signaling by EGFR 46 1.61e-02 0.205000 5.18e-02
p75 NTR receptor-mediated signalling 89 1.61e-02 0.148000 5.18e-02
Senescence-Associated Secretory Phenotype (SASP) 66 1.64e-02 0.171000 5.25e-02
Aquaporin-mediated transport 37 1.64e-02 0.228000 5.25e-02
Hedgehog ligand biogenesis 58 1.65e-02 0.182000 5.27e-02
Regulation of TP53 Activity 151 1.68e-02 -0.113000 5.33e-02
Glucagon signaling in metabolic regulation 27 1.72e-02 0.265000 5.46e-02
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function 53 1.74e-02 0.189000 5.51e-02
Binding and Uptake of Ligands by Scavenger Receptors 92 1.75e-02 -0.143000 5.52e-02
PLC beta mediated events 43 1.76e-02 0.209000 5.55e-02
Mismatch Repair 15 1.78e-02 -0.353000 5.60e-02
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 32 1.81e-02 0.241000 5.68e-02
RNA Polymerase III Chain Elongation 18 1.82e-02 -0.322000 5.69e-02
G-protein mediated events 44 1.86e-02 0.205000 5.80e-02
Interleukin-10 signaling 34 1.86e-02 0.233000 5.80e-02
Early Phase of HIV Life Cycle 14 1.88e-02 -0.363000 5.84e-02
Chemokine receptors bind chemokines 37 1.89e-02 -0.223000 5.86e-02
O-linked glycosylation of mucins 47 1.90e-02 0.198000 5.86e-02
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 38 1.93e-02 -0.219000 5.96e-02
SLC-mediated transmembrane transport 180 1.98e-02 0.101000 6.09e-02
Glycogen breakdown (glycogenolysis) 13 1.99e-02 0.373000 6.13e-02
Activated NOTCH1 Transmits Signal to the Nucleus 27 2.00e-02 0.259000 6.14e-02
Iron uptake and transport 52 2.03e-02 0.186000 6.20e-02
Plasma lipoprotein clearance 29 2.04e-02 0.249000 6.21e-02
HSP90 chaperone cycle for steroid hormone receptors (SHR) 36 2.04e-02 0.223000 6.22e-02
Pentose phosphate pathway 13 2.07e-02 0.370000 6.30e-02
Defective CFTR causes cystic fibrosis 59 2.11e-02 0.174000 6.41e-02
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 14 2.13e-02 -0.355000 6.43e-02
SUMOylation 165 2.19e-02 -0.103000 6.62e-02
Chondroitin sulfate biosynthesis 12 2.22e-02 0.381000 6.68e-02
Response of Mtb to phagocytosis 22 2.24e-02 0.281000 6.72e-02
Developmental Biology 727 2.27e-02 0.049600 6.80e-02
MET promotes cell motility 26 2.28e-02 0.258000 6.82e-02
Cross-presentation of soluble exogenous antigens (endosomes) 47 2.30e-02 0.192000 6.85e-02
MAPK1/MAPK3 signaling 235 2.31e-02 0.086000 6.88e-02
DARPP-32 events 22 2.31e-02 0.280000 6.88e-02
Macroautophagy 110 2.33e-02 0.125000 6.92e-02
Transcriptional regulation by RUNX2 101 2.37e-02 0.130000 7.00e-02
Base Excision Repair 58 2.39e-02 -0.171000 7.07e-02
G alpha (i) signalling events 244 2.46e-02 0.083600 7.23e-02
RET signaling 32 2.46e-02 0.230000 7.23e-02
DAP12 interactions 39 2.47e-02 0.208000 7.23e-02
Infection with Mycobacterium tuberculosis 26 2.48e-02 0.254000 7.25e-02
Stimuli-sensing channels 73 2.55e-02 0.151000 7.44e-02
SARS-CoV-1 Infection 47 2.58e-02 0.188000 7.52e-02
RNA Polymerase III Transcription Initiation 36 2.61e-02 -0.214000 7.58e-02
SUMOylation of DNA replication proteins 46 2.61e-02 -0.190000 7.58e-02
Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 53 2.66e-02 0.176000 7.70e-02
Potential therapeutics for SARS 36 2.67e-02 0.213000 7.72e-02
Vasopressin regulates renal water homeostasis via Aquaporins 34 2.68e-02 0.219000 7.74e-02
Diseases of carbohydrate metabolism 29 2.70e-02 0.237000 7.77e-02
Protein folding 90 2.73e-02 0.135000 7.84e-02
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 51 2.79e-02 0.178000 7.98e-02
Chaperonin-mediated protein folding 84 2.83e-02 0.138000 8.08e-02
UCH proteinases 86 2.86e-02 0.137000 8.15e-02
Oncogene Induced Senescence 33 2.87e-02 0.220000 8.15e-02
Carboxyterminal post-translational modifications of tubulin 26 2.87e-02 0.248000 8.15e-02
DNA Double-Strand Break Repair 135 2.98e-02 -0.108000 8.46e-02
IRAK1 recruits IKK complex 10 3.02e-02 0.396000 8.52e-02
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 10 3.02e-02 0.396000 8.52e-02
ISG15 antiviral mechanism 72 3.02e-02 -0.148000 8.52e-02
Dectin-2 family 19 3.03e-02 0.287000 8.53e-02
Hedgehog 'on' state 75 3.07e-02 0.144000 8.60e-02
G alpha (z) signalling events 36 3.07e-02 0.208000 8.60e-02
p130Cas linkage to MAPK signaling for integrins 11 3.09e-02 0.376000 8.65e-02
Death Receptor Signalling 132 3.10e-02 0.109000 8.66e-02
Complement cascade 99 3.13e-02 -0.125000 8.70e-02
NOTCH3 Intracellular Domain Regulates Transcription 20 3.15e-02 0.278000 8.75e-02
Potassium Channels 63 3.16e-02 0.157000 8.77e-02
Post-chaperonin tubulin folding pathway 19 3.18e-02 0.285000 8.79e-02
SUMOylation of ubiquitinylation proteins 39 3.19e-02 -0.199000 8.80e-02
Calnexin/calreticulin cycle 26 3.21e-02 0.243000 8.84e-02
Disassembly of the destruction complex and recruitment of AXIN to the membrane 29 3.27e-02 0.229000 8.98e-02
Translesion Synthesis by POLH 18 3.30e-02 -0.290000 9.06e-02
Bile acid and bile salt metabolism 29 3.33e-02 0.228000 9.12e-02
InlB-mediated entry of Listeria monocytogenes into host cell 12 3.35e-02 0.354000 9.15e-02
ERK/MAPK targets 22 3.40e-02 0.261000 9.29e-02
Regulation of Complement cascade 95 3.42e-02 -0.126000 9.32e-02
Transcriptional regulation by RUNX3 90 3.44e-02 0.129000 9.34e-02
SUMO E3 ligases SUMOylate target proteins 159 3.45e-02 -0.097200 9.35e-02
Glycogen metabolism 23 3.46e-02 0.255000 9.36e-02
Mitotic G1 phase and G1/S transition 148 3.50e-02 -0.100000 9.45e-02
RAF/MAP kinase cascade 230 3.61e-02 0.080200 9.73e-02
G beta:gamma signalling through CDC42 17 3.62e-02 0.293000 9.75e-02
Signaling by Leptin 10 3.66e-02 0.382000 9.82e-02
CLEC7A (Dectin-1) signaling 96 3.67e-02 0.123000 9.82e-02
Plasma lipoprotein remodeling 18 3.77e-02 0.283000 1.01e-01
Hh mutants abrogate ligand secretion 54 3.84e-02 0.163000 1.02e-01
Adaptive Immune System 756 3.94e-02 0.044000 1.05e-01
Regulation of IFNA signaling 12 4.03e-02 0.342000 1.07e-01
Mitotic Prometaphase 185 4.05e-02 -0.087400 1.07e-01
EPHA-mediated growth cone collapse 13 4.09e-02 0.327000 1.08e-01
Signal regulatory protein family interactions 12 4.17e-02 0.340000 1.10e-01
Homology Directed Repair 110 4.17e-02 -0.112000 1.10e-01
RNA Polymerase III Abortive And Retractive Initiation 41 4.19e-02 -0.184000 1.10e-01
RNA Polymerase III Transcription 41 4.19e-02 -0.184000 1.10e-01
ADP signalling through P2Y purinoceptor 12 18 4.24e-02 0.276000 1.11e-01
Regulation of ornithine decarboxylase (ODC) 49 4.24e-02 0.168000 1.11e-01
ABC transporter disorders 70 4.25e-02 0.140000 1.11e-01
Gluconeogenesis 28 4.27e-02 0.221000 1.11e-01
PINK1-PRKN Mediated Mitophagy 21 4.29e-02 -0.255000 1.12e-01
RNA Polymerase III Transcription Termination 23 4.30e-02 -0.244000 1.12e-01
Gastrin-CREB signalling pathway via PKC and MAPK 14 4.34e-02 0.312000 1.13e-01
Activation of Matrix Metalloproteinases 23 4.37e-02 0.243000 1.13e-01
Antiviral mechanism by IFN-stimulated genes 80 4.44e-02 -0.130000 1.15e-01
Metabolism of steroid hormones 20 4.50e-02 0.259000 1.16e-01
DNA Replication Pre-Initiation 82 4.52e-02 -0.128000 1.16e-01
Ub-specific processing proteases 170 4.52e-02 0.089000 1.16e-01
Interleukin-2 family signaling 38 4.53e-02 0.188000 1.16e-01
Defects in vitamin and cofactor metabolism 21 4.55e-02 -0.252000 1.16e-01
Arachidonic acid metabolism 43 4.58e-02 0.176000 1.17e-01
G-protein activation 23 4.60e-02 0.240000 1.17e-01
Activation of G protein gated Potassium channels 19 4.62e-02 0.264000 1.17e-01
G protein gated Potassium channels 19 4.62e-02 0.264000 1.17e-01
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 19 4.62e-02 0.264000 1.17e-01
PKA activation in glucagon signalling 14 4.67e-02 0.307000 1.18e-01
Signaling by FGFR1 38 4.70e-02 0.186000 1.19e-01
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 53 4.74e-02 0.157000 1.19e-01
Constitutive Signaling by NOTCH1 PEST Domain Mutants 53 4.74e-02 0.157000 1.19e-01
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 53 4.74e-02 0.157000 1.19e-01
Signaling by NOTCH1 PEST Domain Mutants in Cancer 53 4.74e-02 0.157000 1.19e-01
Signaling by NOTCH1 in Cancer 53 4.74e-02 0.157000 1.19e-01
GAB1 signalosome 15 4.79e-02 0.295000 1.19e-01
Diseases of DNA repair 10 4.87e-02 -0.360000 1.21e-01
Folding of actin by CCT/TriC 10 4.90e-02 -0.360000 1.22e-01
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 80 4.92e-02 0.127000 1.22e-01
Presynaptic function of Kainate receptors 18 5.03e-02 0.266000 1.25e-01
Metabolism of amine-derived hormones 10 5.10e-02 -0.356000 1.26e-01
Interleukin receptor SHC signaling 23 5.11e-02 0.235000 1.26e-01
Metabolism of porphyrins 22 5.21e-02 0.239000 1.28e-01
Olfactory Signaling Pathway 58 5.21e-02 0.147000 1.28e-01
Cell Cycle, Mitotic 502 5.21e-02 -0.050600 1.28e-01
G alpha (q) signalling events 131 5.23e-02 0.098200 1.28e-01
N-glycan trimming in the ER and Calnexin/Calreticulin cycle 35 5.23e-02 0.190000 1.28e-01
Misspliced GSK3beta mutants stabilize beta-catenin 15 5.30e-02 0.289000 1.28e-01
S33 mutants of beta-catenin aren't phosphorylated 15 5.30e-02 0.289000 1.28e-01
S37 mutants of beta-catenin aren't phosphorylated 15 5.30e-02 0.289000 1.28e-01
S45 mutants of beta-catenin aren't phosphorylated 15 5.30e-02 0.289000 1.28e-01
T41 mutants of beta-catenin aren't phosphorylated 15 5.30e-02 0.289000 1.28e-01
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 15 5.30e-02 0.289000 1.28e-01
RNA Polymerase III Transcription Initiation From Type 3 Promoter 28 5.36e-02 -0.211000 1.30e-01
Common Pathway of Fibrin Clot Formation 14 5.37e-02 0.298000 1.30e-01
Negative regulation of FGFR1 signaling 24 5.51e-02 0.226000 1.33e-01
IKK complex recruitment mediated by RIP1 23 5.52e-02 0.231000 1.33e-01
Apoptotic cleavage of cellular proteins 34 5.54e-02 0.190000 1.33e-01
Constitutive Signaling by AKT1 E17K in Cancer 25 5.55e-02 0.221000 1.33e-01
Activation of HOX genes during differentiation 68 5.56e-02 0.134000 1.33e-01
Activation of anterior HOX genes in hindbrain development during early embryogenesis 68 5.56e-02 0.134000 1.33e-01
GRB2:SOS provides linkage to MAPK signaling for Integrins 12 5.56e-02 0.319000 1.33e-01
FCERI mediated MAPK activation 90 5.57e-02 -0.117000 1.33e-01
Myogenesis 21 5.60e-02 0.241000 1.33e-01
Degradation of DVL 54 5.61e-02 0.150000 1.33e-01
Interconversion of nucleotide di- and triphosphates 27 5.78e-02 -0.211000 1.37e-01
Formation of the cornified envelope 21 5.84e-02 0.239000 1.38e-01
Interleukin-6 signaling 10 5.85e-02 0.346000 1.38e-01
Fcgamma receptor (FCGR) dependent phagocytosis 147 5.88e-02 0.090300 1.38e-01
Retinoid metabolism and transport 24 5.91e-02 0.223000 1.39e-01
Adenylate cyclase inhibitory pathway 11 5.99e-02 0.328000 1.41e-01
Degradation of beta-catenin by the destruction complex 83 6.01e-02 0.119000 1.41e-01
Uptake and actions of bacterial toxins 27 6.02e-02 0.209000 1.41e-01
Transcriptional regulation by RUNX1 184 6.06e-02 0.080200 1.41e-01
Signaling by Non-Receptor Tyrosine Kinases 48 6.06e-02 0.157000 1.41e-01
Signaling by PTK6 48 6.06e-02 0.157000 1.41e-01
Cell Cycle Checkpoints 259 6.16e-02 -0.067500 1.43e-01
Thromboxane signalling through TP receptor 20 6.17e-02 0.241000 1.43e-01
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) 12 6.18e-02 0.311000 1.43e-01
Diseases of hemostasis 12 6.18e-02 0.311000 1.43e-01
Transcription of E2F targets under negative control by DREAM complex 19 6.32e-02 -0.246000 1.46e-01
Beta-oxidation of very long chain fatty acids 10 6.34e-02 0.339000 1.46e-01
Surfactant metabolism 21 6.35e-02 0.234000 1.46e-01
Degradation of GLI1 by the proteasome 57 6.35e-02 0.142000 1.46e-01
G beta:gamma signalling through BTK 15 6.41e-02 0.276000 1.47e-01
Regulation of TP53 Activity through Phosphorylation 88 6.46e-02 -0.114000 1.48e-01
Regulation of activated PAK-2p34 by proteasome mediated degradation 48 6.53e-02 0.154000 1.49e-01
NOTCH4 Intracellular Domain Regulates Transcription 17 6.77e-02 0.256000 1.54e-01
G beta:gamma signalling through PLC beta 17 6.83e-02 0.255000 1.55e-01
MAPK targets/ Nuclear events mediated by MAP kinases 31 6.84e-02 0.189000 1.55e-01
RUNX3 regulates NOTCH signaling 14 6.92e-02 0.281000 1.57e-01
Nuclear Envelope Breakdown 53 6.95e-02 -0.144000 1.57e-01
mRNA 3'-end processing 56 6.95e-02 -0.140000 1.57e-01
Negative regulation of NOTCH4 signaling 54 7.02e-02 0.142000 1.58e-01
TRAF6 mediated NF-kB activation 23 7.03e-02 0.218000 1.58e-01
Peroxisomal protein import 57 7.04e-02 0.139000 1.58e-01
NOTCH3 Activation and Transmission of Signal to the Nucleus 23 7.05e-02 0.218000 1.58e-01
Packaging Of Telomere Ends 20 7.06e-02 0.234000 1.58e-01
Regulation of FZD by ubiquitination 15 7.17e-02 -0.269000 1.60e-01
Extra-nuclear estrogen signaling 67 7.23e-02 0.127000 1.62e-01
HDR through MMEJ (alt-NHEJ) 10 7.32e-02 -0.327000 1.63e-01
Ca-dependent events 29 7.34e-02 0.192000 1.63e-01
The NLRP3 inflammasome 15 7.36e-02 0.267000 1.64e-01
Sphingolipid de novo biosynthesis 41 7.38e-02 0.161000 1.64e-01
Endogenous sterols 17 7.45e-02 0.250000 1.65e-01
Protein ubiquitination 72 7.48e-02 0.121000 1.66e-01
Pyrimidine salvage 10 7.49e-02 0.325000 1.66e-01
TAK1 activates NFkB by phosphorylation and activation of IKKs complex 27 7.52e-02 0.198000 1.66e-01
Gene Silencing by RNA 87 7.73e-02 -0.110000 1.70e-01
Cell death signalling via NRAGE, NRIF and NADE 70 7.76e-02 0.122000 1.71e-01
E2F mediated regulation of DNA replication 22 7.79e-02 -0.217000 1.71e-01
Vif-mediated degradation of APOBEC3G 52 7.88e-02 0.141000 1.72e-01
Nucleotide salvage 21 7.88e-02 0.222000 1.72e-01
RHO GTPases activate KTN1 11 7.89e-02 0.306000 1.72e-01
Sialic acid metabolism 28 7.95e-02 0.191000 1.73e-01
Negative regulation of the PI3K/AKT network 87 7.98e-02 0.109000 1.74e-01
Rap1 signalling 13 8.18e-02 0.279000 1.78e-01
Suppression of phagosomal maturation 12 8.26e-02 0.289000 1.79e-01
MAPK6/MAPK4 signaling 82 8.26e-02 0.111000 1.79e-01
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15 8.29e-02 0.259000 1.79e-01
Processing of Capped Intronless Pre-mRNA 28 8.38e-02 -0.189000 1.81e-01
Cardiac conduction 92 8.40e-02 0.104000 1.81e-01
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 14 8.42e-02 0.267000 1.81e-01
Triglyceride catabolism 16 8.46e-02 0.249000 1.82e-01
Circadian Clock 67 8.49e-02 0.122000 1.82e-01
Inactivation of APC/C via direct inhibition of the APC/C complex 21 8.68e-02 -0.216000 1.86e-01
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 21 8.68e-02 -0.216000 1.86e-01
FCERI mediated NF-kB activation 137 8.72e-02 -0.084600 1.86e-01
ZBP1(DAI) mediated induction of type I IFNs 20 8.78e-02 0.220000 1.87e-01
TP53 Regulates Metabolic Genes 84 8.83e-02 0.108000 1.88e-01
Elastic fibre formation 32 9.00e-02 0.173000 1.91e-01
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol 16 9.01e-02 0.245000 1.91e-01
Retrograde transport at the Trans-Golgi-Network 49 9.02e-02 0.140000 1.91e-01
APC-Cdc20 mediated degradation of Nek2A 26 9.07e-02 -0.192000 1.92e-01
Formation of Incision Complex in GG-NER 43 9.14e-02 -0.149000 1.93e-01
ATF6 (ATF6-alpha) activates chaperones 12 9.25e-02 0.281000 1.95e-01
Assembly of collagen fibrils and other multimeric structures 42 9.28e-02 0.150000 1.95e-01
GPCR ligand binding 229 9.37e-02 0.064300 1.97e-01
Regulation of RAS by GAPs 66 9.41e-02 0.119000 1.98e-01
Degradation of GLI2 by the proteasome 56 9.69e-02 0.128000 2.03e-01
Epigenetic regulation of gene expression 103 9.73e-02 -0.094600 2.04e-01
Activation of NF-kappaB in B cells 65 9.75e-02 0.119000 2.04e-01
Signaling by TGF-beta Receptor Complex 72 9.86e-02 0.113000 2.06e-01
G0 and Early G1 27 9.91e-02 -0.183000 2.07e-01
RIP-mediated NFkB activation via ZBP1 17 9.98e-02 0.231000 2.08e-01
Signaling by cytosolic FGFR1 fusion mutants 18 1.01e-01 0.224000 2.09e-01
FGFR1 mutant receptor activation 24 1.01e-01 0.194000 2.09e-01
RUNX2 regulates bone development 23 1.01e-01 0.198000 2.09e-01
Signaling by FGFR3 31 1.01e-01 0.170000 2.09e-01
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12 1.01e-01 0.273000 2.09e-01
Assembly Of The HIV Virion 15 1.01e-01 0.244000 2.09e-01
Biotin transport and metabolism 11 1.02e-01 -0.285000 2.09e-01
Acyl chain remodelling of PC 19 1.02e-01 0.217000 2.09e-01
Antigen processing: Ubiquitination & Proteasome degradation 288 1.03e-01 0.055800 2.12e-01
Long-term potentiation 14 1.04e-01 -0.251000 2.13e-01
Glutamate and glutamine metabolism 12 1.04e-01 -0.271000 2.13e-01
Membrane binding and targetting of GAG proteins 13 1.05e-01 0.260000 2.13e-01
Synthesis And Processing Of GAG, GAGPOL Polyproteins 13 1.05e-01 0.260000 2.13e-01
SUMOylation of immune response proteins 11 1.05e-01 0.283000 2.13e-01
Inositol phosphate metabolism 42 1.05e-01 0.145000 2.13e-01
Scavenging by Class A Receptors 11 1.05e-01 0.282000 2.13e-01
ER Quality Control Compartment (ERQC) 21 1.06e-01 0.204000 2.13e-01
AMER1 mutants destabilize the destruction complex 14 1.06e-01 0.250000 2.13e-01
APC truncation mutants have impaired AXIN binding 14 1.06e-01 0.250000 2.13e-01
AXIN missense mutants destabilize the destruction complex 14 1.06e-01 0.250000 2.13e-01
AXIN mutants destabilize the destruction complex, activating WNT signaling 14 1.06e-01 0.250000 2.13e-01
Truncations of AMER1 destabilize the destruction complex 14 1.06e-01 0.250000 2.13e-01
truncated APC mutants destabilize the destruction complex 14 1.06e-01 0.250000 2.13e-01
RNA Polymerase I Promoter Clearance 66 1.06e-01 -0.115000 2.13e-01
RNA Polymerase I Transcription 66 1.06e-01 -0.115000 2.13e-01
Unfolded Protein Response (UPR) 86 1.07e-01 0.101000 2.13e-01
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 52 1.07e-01 0.129000 2.14e-01
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 104 1.07e-01 -0.091400 2.14e-01
MET activates RAS signaling 10 1.08e-01 0.294000 2.15e-01
Signaling by WNT in cancer 30 1.08e-01 0.169000 2.15e-01
PIWI-interacting RNA (piRNA) biogenesis 23 1.09e-01 -0.193000 2.16e-01
Signaling by Hedgehog 120 1.09e-01 0.084800 2.16e-01
Diseases associated with glycosylation precursor biosynthesis 18 1.09e-01 0.218000 2.16e-01
Regulation of Apoptosis 51 1.10e-01 0.129000 2.17e-01
NOD1/2 Signaling Pathway 32 1.10e-01 0.163000 2.17e-01
E3 ubiquitin ligases ubiquitinate target proteins 52 1.10e-01 0.128000 2.18e-01
Adherens junctions interactions 18 1.11e-01 0.217000 2.19e-01
SHC1 events in EGFR signaling 12 1.11e-01 0.265000 2.19e-01
Regulation of RUNX3 expression and activity 55 1.11e-01 0.124000 2.19e-01
Signaling by Hippo 18 1.12e-01 0.216000 2.19e-01
CD28 dependent PI3K/Akt signaling 22 1.13e-01 -0.195000 2.21e-01
SUMOylation of intracellular receptors 25 1.14e-01 0.182000 2.24e-01
Interleukin-15 signaling 14 1.15e-01 0.243000 2.24e-01
Glutamate binding, activation of AMPA receptors and synaptic plasticity 20 1.15e-01 0.203000 2.24e-01
Trafficking of AMPA receptors 20 1.15e-01 0.203000 2.24e-01
ATF6 (ATF6-alpha) activates chaperone genes 10 1.15e-01 0.288000 2.24e-01
Interleukin-37 signaling 19 1.16e-01 0.208000 2.26e-01
Inflammasomes 20 1.17e-01 0.203000 2.26e-01
Negative regulation of MAPK pathway 42 1.17e-01 0.140000 2.26e-01
Formation of Fibrin Clot (Clotting Cascade) 26 1.18e-01 0.177000 2.28e-01
Assembly and cell surface presentation of NMDA receptors 18 1.19e-01 -0.212000 2.30e-01
Metabolism of fat-soluble vitamins 28 1.20e-01 0.170000 2.31e-01
Apoptosis induced DNA fragmentation 10 1.20e-01 0.284000 2.31e-01
Interleukin-12 family signaling 53 1.20e-01 0.123000 2.31e-01
Telomere Extension By Telomerase 23 1.20e-01 -0.187000 2.31e-01
Condensation of Prophase Chromosomes 29 1.20e-01 0.167000 2.31e-01
Plasma lipoprotein assembly 10 1.21e-01 0.283000 2.31e-01
Antigen Presentation: Folding, assembly and peptide loading of class I MHC 25 1.23e-01 0.178000 2.35e-01
Formation of the beta-catenin:TCF transactivating complex 46 1.23e-01 0.131000 2.35e-01
Downstream signal transduction 27 1.23e-01 0.171000 2.35e-01
Peptide ligand-binding receptors 92 1.24e-01 0.092800 2.36e-01
AUF1 (hnRNP D0) binds and destabilizes mRNA 53 1.25e-01 0.122000 2.37e-01
Metalloprotease DUBs 21 1.25e-01 0.193000 2.37e-01
Negative regulation of FGFR3 signaling 20 1.25e-01 0.198000 2.37e-01
Mitotic Spindle Checkpoint 108 1.26e-01 -0.085300 2.38e-01
Mitophagy 28 1.28e-01 -0.166000 2.42e-01
Listeria monocytogenes entry into host cells 17 1.29e-01 0.213000 2.43e-01
Anchoring of the basal body to the plasma membrane 97 1.29e-01 -0.089100 2.43e-01
The role of GTSE1 in G2/M progression after G2 checkpoint 58 1.29e-01 0.115000 2.43e-01
Cholesterol biosynthesis 24 1.30e-01 0.179000 2.44e-01
NOTCH1 Intracellular Domain Regulates Transcription 44 1.30e-01 0.132000 2.45e-01
tRNA processing in the mitochondrion 30 1.31e-01 -0.159000 2.45e-01
mTORC1-mediated signalling 23 1.31e-01 0.182000 2.45e-01
Metabolism of nucleotides 86 1.32e-01 -0.094000 2.46e-01
Initiation of Nuclear Envelope (NE) Reformation 19 1.33e-01 0.199000 2.47e-01
NOTCH2 intracellular domain regulates transcription 11 1.33e-01 0.262000 2.48e-01
DNA Damage/Telomere Stress Induced Senescence 44 1.34e-01 0.131000 2.50e-01
Triglyceride metabolism 25 1.35e-01 0.173000 2.50e-01
Striated Muscle Contraction 23 1.37e-01 0.179000 2.55e-01
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 36 1.39e-01 0.142000 2.58e-01
Positive epigenetic regulation of rRNA expression 62 1.39e-01 -0.109000 2.58e-01
NCAM1 interactions 23 1.40e-01 -0.178000 2.59e-01
Assembly of active LPL and LIPC lipase complexes 10 1.43e-01 0.267000 2.64e-01
Biosynthesis of specialized proresolving mediators (SPMs) 16 1.43e-01 0.211000 2.64e-01
Asymmetric localization of PCP proteins 60 1.44e-01 0.109000 2.66e-01
Mitochondrial calcium ion transport 22 1.45e-01 -0.179000 2.67e-01
Effects of PIP2 hydrolysis 24 1.45e-01 -0.172000 2.67e-01
FOXO-mediated transcription 58 1.47e-01 0.110000 2.69e-01
Translation of Replicase and Assembly of the Replication Transcription Complex 12 1.47e-01 0.242000 2.69e-01
FGFR2 mutant receptor activation 22 1.47e-01 -0.178000 2.69e-01
GLI3 is processed to GLI3R by the proteasome 57 1.48e-01 0.111000 2.69e-01
Signaling by PDGF 44 1.48e-01 0.126000 2.69e-01
Platelet calcium homeostasis 21 1.48e-01 0.182000 2.69e-01
Tight junction interactions 18 1.48e-01 -0.197000 2.70e-01
Regulation of actin dynamics for phagocytic cup formation 123 1.49e-01 0.075300 2.71e-01
Ubiquitin-dependent degradation of Cyclin D 50 1.50e-01 0.118000 2.72e-01
Synthesis of bile acids and bile salts 24 1.50e-01 0.170000 2.72e-01
HIV Life Cycle 144 1.51e-01 -0.069400 2.73e-01
TRAF6 mediated IRF7 activation 15 1.52e-01 0.213000 2.75e-01
Inwardly rectifying K+ channels 23 1.53e-01 0.172000 2.75e-01
Interleukin-12 signaling 44 1.54e-01 0.124000 2.77e-01
Glycogen synthesis 13 1.54e-01 0.228000 2.77e-01
Collagen biosynthesis and modifying enzymes 48 1.55e-01 0.119000 2.78e-01
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 17 1.55e-01 -0.199000 2.78e-01
Activation of BAD and translocation to mitochondria 15 1.56e-01 0.212000 2.78e-01
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 50 1.56e-01 0.116000 2.78e-01
p53-Independent DNA Damage Response 50 1.56e-01 0.116000 2.78e-01
p53-Independent G1/S DNA damage checkpoint 50 1.56e-01 0.116000 2.78e-01
Degradation of AXIN 53 1.56e-01 0.113000 2.78e-01
Cleavage of the damaged purine 24 1.57e-01 0.167000 2.79e-01
Depurination 24 1.57e-01 0.167000 2.79e-01
Recognition and association of DNA glycosylase with site containing an affected purine 24 1.57e-01 0.167000 2.79e-01
Defects in cobalamin (B12) metabolism 13 1.57e-01 -0.227000 2.79e-01
Cytochrome c-mediated apoptotic response 13 1.58e-01 0.226000 2.79e-01
Interleukin-27 signaling 11 1.58e-01 0.246000 2.79e-01
VEGFR2 mediated vascular permeability 27 1.58e-01 0.157000 2.79e-01
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20 1.59e-01 -0.182000 2.80e-01
Recruitment of NuMA to mitotic centrosomes 80 1.61e-01 -0.090700 2.83e-01
Downstream TCR signaling 100 1.63e-01 -0.080700 2.87e-01
NGF-stimulated transcription 31 1.64e-01 0.144000 2.89e-01
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 17 1.65e-01 -0.194000 2.90e-01
KSRP (KHSRP) binds and destabilizes mRNA 17 1.66e-01 -0.194000 2.91e-01
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 16 1.68e-01 -0.199000 2.95e-01
EGR2 and SOX10-mediated initiation of Schwann cell myelination 22 1.70e-01 0.169000 2.97e-01
Formation of TC-NER Pre-Incision Complex 53 1.70e-01 -0.109000 2.97e-01
Caspase activation via Death Receptors in the presence of ligand 16 1.70e-01 0.198000 2.97e-01
NIK-->noncanonical NF-kB signaling 57 1.71e-01 0.105000 2.97e-01
Fatty acyl-CoA biosynthesis 34 1.73e-01 0.135000 3.01e-01
Regulation of mRNA stability by proteins that bind AU-rich elements 87 1.74e-01 0.084300 3.03e-01
Processing of SMDT1 15 1.75e-01 -0.202000 3.03e-01
Host Interactions of HIV factors 129 1.75e-01 -0.069200 3.03e-01
Insulin processing 21 1.76e-01 0.170000 3.05e-01
Signaling by TGFB family members 91 1.78e-01 0.081800 3.07e-01
Class A/1 (Rhodopsin-like receptors) 162 1.78e-01 0.061300 3.08e-01
HuR (ELAVL1) binds and stabilizes mRNA 10 1.78e-01 0.246000 3.08e-01
Regulation of TP53 Activity through Acetylation 29 1.80e-01 -0.144000 3.09e-01
Dectin-1 mediated noncanonical NF-kB signaling 58 1.80e-01 0.102000 3.09e-01
Protein localization 157 1.80e-01 -0.062000 3.09e-01
Signaling by FGFR1 in disease 31 1.81e-01 0.139000 3.09e-01
A tetrasaccharide linker sequence is required for GAG synthesis 17 1.81e-01 -0.188000 3.09e-01
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 17 1.85e-01 0.186000 3.16e-01
Centrosome maturation 81 1.85e-01 -0.085200 3.16e-01
Recruitment of mitotic centrosome proteins and complexes 81 1.85e-01 -0.085200 3.16e-01
PKA activation 15 1.86e-01 0.197000 3.17e-01
RUNX3 regulates p14-ARF 10 1.86e-01 0.241000 3.17e-01
Butyrophilin (BTN) family interactions 10 1.86e-01 -0.241000 3.17e-01
TRAF6-mediated induction of TAK1 complex within TLR4 complex 16 1.86e-01 0.191000 3.17e-01
TGF-beta receptor signaling activates SMADs 32 1.87e-01 0.135000 3.17e-01
Neddylation 218 1.87e-01 0.051800 3.17e-01
Metabolism of polyamines 57 1.88e-01 0.101000 3.17e-01
Ion transport by P-type ATPases 42 1.88e-01 0.117000 3.18e-01
Negative regulation of FGFR4 signaling 21 1.88e-01 0.166000 3.18e-01
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 72 1.88e-01 0.089600 3.18e-01
Prostacyclin signalling through prostacyclin receptor 16 1.89e-01 0.190000 3.18e-01
Formation of Senescence-Associated Heterochromatin Foci (SAHF) 13 1.89e-01 0.210000 3.18e-01
Formation of apoptosome 11 1.90e-01 0.228000 3.20e-01
Regulation of the apoptosome activity 11 1.90e-01 0.228000 3.20e-01
Signaling by the B Cell Receptor (BCR) 162 1.92e-01 -0.059400 3.22e-01
Cytosolic iron-sulfur cluster assembly 13 1.92e-01 -0.209000 3.22e-01
Estrogen-dependent gene expression 99 1.93e-01 0.075700 3.23e-01
Transcriptional regulation of pluripotent stem cells 19 1.94e-01 0.172000 3.24e-01
NRAGE signals death through JNK 53 1.94e-01 0.103000 3.24e-01
ABC-family proteins mediated transport 93 1.96e-01 0.077600 3.26e-01
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane 22 1.96e-01 0.159000 3.26e-01
Processing of DNA double-strand break ends 71 1.98e-01 -0.088400 3.28e-01
Signaling by NOTCH2 30 1.98e-01 0.136000 3.29e-01
Peroxisomal lipid metabolism 27 1.99e-01 0.143000 3.30e-01
Platelet Adhesion to exposed collagen 13 2.01e-01 0.205000 3.33e-01
The role of Nef in HIV-1 replication and disease pathogenesis 28 2.04e-01 0.139000 3.37e-01
APC/C:Cdc20 mediated degradation of Cyclin B 24 2.05e-01 -0.150000 3.37e-01
Transport of vitamins, nucleosides, and related molecules 33 2.05e-01 0.128000 3.37e-01
Inhibition of DNA recombination at telomere 35 2.05e-01 0.124000 3.37e-01
Signaling by ERBB4 44 2.09e-01 0.110000 3.43e-01
Signaling by FGFR4 31 2.09e-01 0.130000 3.43e-01
Keratinization 32 2.10e-01 0.128000 3.45e-01
HCMV Early Events 74 2.11e-01 -0.084100 3.46e-01
CaM pathway 27 2.12e-01 0.139000 3.47e-01
Calmodulin induced events 27 2.12e-01 0.139000 3.47e-01
Signaling by FGFR2 in disease 32 2.12e-01 -0.127000 3.47e-01
Regulation of beta-cell development 19 2.13e-01 0.165000 3.48e-01
TP53 Regulates Transcription of DNA Repair Genes 61 2.14e-01 -0.092000 3.49e-01
Regulation of TP53 Activity through Methylation 19 2.16e-01 -0.164000 3.51e-01
G2/M Checkpoints 139 2.17e-01 -0.060600 3.53e-01
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 20 2.17e-01 -0.159000 3.53e-01
GRB2 events in EGFR signaling 11 2.17e-01 0.215000 3.53e-01
Cell-extracellular matrix interactions 14 2.21e-01 0.189000 3.58e-01
Glutathione conjugation 26 2.21e-01 0.139000 3.58e-01
Interleukin-6 family signaling 18 2.24e-01 0.166000 3.62e-01
SUMOylation of DNA methylation proteins 16 2.24e-01 -0.176000 3.62e-01
Insulin receptor signalling cascade 39 2.25e-01 0.112000 3.63e-01
Autodegradation of the E3 ubiquitin ligase COP1 49 2.26e-01 0.099900 3.65e-01
Glycogen storage diseases 13 2.27e-01 0.194000 3.65e-01
Josephin domain DUBs 10 2.27e-01 0.220000 3.65e-01
Synthesis of PIPs at the Golgi membrane 16 2.28e-01 0.174000 3.66e-01
FCGR3A-mediated phagocytosis 121 2.31e-01 0.063000 3.70e-01
Leishmania phagocytosis 121 2.31e-01 0.063000 3.70e-01
Parasite infection 121 2.31e-01 0.063000 3.70e-01
Heparan sulfate/heparin (HS-GAG) metabolism 37 2.32e-01 0.114000 3.70e-01
Trafficking and processing of endosomal TLR 13 2.33e-01 0.191000 3.72e-01
Glyoxylate metabolism and glycine degradation 24 2.34e-01 -0.140000 3.73e-01
Diseases of metabolism 190 2.35e-01 0.050000 3.74e-01
FGFR2 alternative splicing 25 2.36e-01 -0.137000 3.75e-01
Tie2 Signaling 16 2.38e-01 0.171000 3.77e-01
Activation of kainate receptors upon glutamate binding 26 2.39e-01 0.134000 3.78e-01
Vpu mediated degradation of CD4 50 2.39e-01 0.096200 3.79e-01
Citric acid cycle (TCA cycle) 22 2.40e-01 0.145000 3.79e-01
Synthesis of IP3 and IP4 in the cytosol 22 2.40e-01 0.145000 3.79e-01
The phototransduction cascade 25 2.40e-01 -0.136000 3.79e-01
Regulation of MECP2 expression and activity 28 2.42e-01 0.128000 3.82e-01
mRNA decay by 5' to 3' exoribonuclease 15 2.45e-01 -0.174000 3.85e-01
MAP3K8 (TPL2)-dependent MAPK1/3 activation 16 2.46e-01 0.168000 3.87e-01
Cobalamin (Cbl, vitamin B12) transport and metabolism 16 2.46e-01 -0.167000 3.87e-01
HCMV Late Events 69 2.46e-01 0.080700 3.87e-01
Transcriptional Regulation by MECP2 47 2.48e-01 0.097400 3.89e-01
Signaling by PDGFRA extracellular domain mutants 12 2.49e-01 0.192000 3.89e-01
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants 12 2.49e-01 0.192000 3.89e-01
Nicotinate metabolism 25 2.49e-01 0.133000 3.89e-01
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 91 2.52e-01 -0.069500 3.92e-01
Amplification of signal from the kinetochores 91 2.52e-01 -0.069500 3.92e-01
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 17 2.52e-01 -0.161000 3.92e-01
ECM proteoglycans 35 2.53e-01 0.112000 3.93e-01
Integrin cell surface interactions 52 2.53e-01 0.091600 3.93e-01
ADORA2B mediated anti-inflammatory cytokines production 73 2.57e-01 0.076800 3.98e-01
Ca2+ pathway 57 2.57e-01 0.086800 3.98e-01
Cellular responses to stress 499 2.59e-01 -0.029500 4.01e-01
DAG and IP3 signaling 33 2.60e-01 0.113000 4.02e-01
Deposition of new CENPA-containing nucleosomes at the centromere 40 2.60e-01 -0.103000 4.02e-01
Nucleosome assembly 40 2.60e-01 -0.103000 4.02e-01
Translation of structural proteins 28 2.61e-01 0.123000 4.03e-01
Glucose metabolism 84 2.66e-01 0.070200 4.09e-01
Keratan sulfate/keratin metabolism 27 2.66e-01 0.124000 4.09e-01
Stabilization of p53 54 2.66e-01 0.087400 4.09e-01
Metabolic disorders of biological oxidation enzymes 25 2.68e-01 0.128000 4.11e-01
Regulation of localization of FOXO transcription factors 11 2.69e-01 0.192000 4.12e-01
Ovarian tumor domain proteases 37 2.69e-01 0.105000 4.12e-01
Meiotic synapsis 45 2.70e-01 0.095000 4.13e-01
Adrenaline,noradrenaline inhibits insulin secretion 24 2.71e-01 0.130000 4.14e-01
Intrinsic Pathway of Fibrin Clot Formation 16 2.73e-01 0.158000 4.17e-01
Switching of origins to a post-replicative state 89 2.76e-01 -0.066900 4.20e-01
Resolution of Sister Chromatid Cohesion 104 2.77e-01 -0.061700 4.22e-01
Vitamin B5 (pantothenate) metabolism 17 2.77e-01 0.152000 4.22e-01
PI-3K cascade:FGFR2 12 2.78e-01 -0.181000 4.22e-01
Synthesis of IP2, IP, and Ins in the cytosol 13 2.80e-01 0.173000 4.25e-01
Cytochrome P450 - arranged by substrate type 34 2.81e-01 0.107000 4.25e-01
Cell-Cell communication 87 2.84e-01 0.066400 4.30e-01
Phase I - Functionalization of compounds 63 2.85e-01 0.077900 4.31e-01
DNA Damage Recognition in GG-NER 38 2.86e-01 -0.100000 4.31e-01
Carnitine metabolism 10 2.86e-01 0.195000 4.31e-01
Cleavage of the damaged pyrimidine 29 2.87e-01 0.114000 4.31e-01
Depyrimidination 29 2.87e-01 0.114000 4.31e-01
Recognition and association of DNA glycosylase with site containing an affected pyrimidine 29 2.87e-01 0.114000 4.31e-01
Downstream signaling events of B Cell Receptor (BCR) 79 2.89e-01 0.069000 4.34e-01
SHC1 events in ERBB2 signaling 17 2.89e-01 0.148000 4.34e-01
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 26 2.90e-01 -0.120000 4.34e-01
Synthesis of active ubiquitin: roles of E1 and E2 enzymes 30 2.90e-01 0.112000 4.34e-01
ATF4 activates genes in response to endoplasmic reticulum stress 25 2.90e-01 -0.122000 4.34e-01
Phosphorylation of the APC/C 20 2.92e-01 -0.136000 4.37e-01
Interleukin-20 family signaling 17 2.93e-01 0.147000 4.37e-01
Activation of the AP-1 family of transcription factors 10 2.97e-01 0.191000 4.42e-01
TICAM1, RIP1-mediated IKK complex recruitment 19 2.99e-01 0.138000 4.44e-01
G2/M DNA damage checkpoint 68 2.99e-01 -0.072900 4.44e-01
PERK regulates gene expression 30 3.00e-01 -0.109000 4.46e-01
HS-GAG biosynthesis 20 3.02e-01 0.133000 4.48e-01
Cell recruitment (pro-inflammatory response) 22 3.03e-01 0.127000 4.49e-01
Purinergic signaling in leishmaniasis infection 22 3.03e-01 0.127000 4.49e-01
SCF-beta-TrCP mediated degradation of Emi1 53 3.04e-01 0.081700 4.49e-01
Intrinsic Pathway for Apoptosis 52 3.06e-01 0.082000 4.53e-01
Metabolism of vitamins and cofactors 155 3.07e-01 0.047500 4.53e-01
PI3K/AKT Signaling in Cancer 80 3.08e-01 0.065900 4.54e-01
Synthesis of PIPs at the late endosome membrane 11 3.09e-01 0.177000 4.54e-01
Constitutive Signaling by EGFRvIII 14 3.09e-01 0.157000 4.54e-01
Signaling by EGFRvIII in Cancer 14 3.09e-01 0.157000 4.54e-01
HSF1 activation 26 3.10e-01 -0.115000 4.54e-01
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 36 3.10e-01 0.097800 4.54e-01
IRF3-mediated induction of type I IFN 12 3.11e-01 -0.169000 4.55e-01
CD209 (DC-SIGN) signaling 20 3.12e-01 0.131000 4.56e-01
Interferon Signaling 177 3.12e-01 -0.044000 4.56e-01
p53-Dependent G1 DNA Damage Response 63 3.13e-01 0.073600 4.56e-01
p53-Dependent G1/S DNA damage checkpoint 63 3.13e-01 0.073600 4.56e-01
TRAF3-dependent IRF activation pathway 13 3.15e-01 0.161000 4.60e-01
Synaptic adhesion-like molecules 14 3.17e-01 0.154000 4.62e-01
Post-translational modification: synthesis of GPI-anchored proteins 57 3.19e-01 0.076300 4.64e-01
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 18 3.21e-01 0.135000 4.66e-01
EML4 and NUDC in mitotic spindle formation 95 3.21e-01 -0.058900 4.66e-01
Disorders of developmental biology 12 3.23e-01 0.165000 4.67e-01
Loss of function of MECP2 in Rett syndrome 12 3.23e-01 0.165000 4.67e-01
Pervasive developmental disorders 12 3.23e-01 0.165000 4.67e-01
Apoptotic factor-mediated response 18 3.23e-01 0.134000 4.67e-01
p38MAPK events 13 3.26e-01 0.157000 4.70e-01
TCR signaling 121 3.28e-01 -0.051500 4.73e-01
Base-Excision Repair, AP Site Formation 31 3.29e-01 0.101000 4.74e-01
Other semaphorin interactions 16 3.31e-01 0.141000 4.76e-01
Regulation of KIT signaling 15 3.32e-01 0.145000 4.78e-01
Nucleobase catabolism 28 3.37e-01 0.105000 4.84e-01
Class B/2 (Secretin family receptors) 56 3.38e-01 0.074000 4.85e-01
Acyl chain remodelling of PI 10 3.38e-01 0.175000 4.85e-01
Cell junction organization 59 3.40e-01 0.071800 4.87e-01
Inactivation, recovery and regulation of the phototransduction cascade 24 3.40e-01 -0.112000 4.87e-01
RA biosynthesis pathway 13 3.41e-01 -0.153000 4.87e-01
Cytosolic sulfonation of small molecules 19 3.42e-01 0.126000 4.87e-01
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13 3.43e-01 0.152000 4.87e-01
Constitutive Signaling by Overexpressed ERBB2 11 3.43e-01 0.165000 4.87e-01
Resolution of D-loop Structures through Holliday Junction Intermediates 32 3.43e-01 -0.096900 4.87e-01
Regulation of PLK1 Activity at G2/M Transition 87 3.43e-01 -0.058800 4.88e-01
Cristae formation 31 3.44e-01 -0.098100 4.89e-01
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 27 3.47e-01 -0.104000 4.92e-01
RNA polymerase II transcribes snRNA genes 72 3.48e-01 0.064000 4.93e-01
APC/C:Cdc20 mediated degradation of Securin 66 3.48e-01 0.066700 4.93e-01
Regulation of TP53 Activity through Association with Co-factors 11 3.49e-01 -0.163000 4.93e-01
Metabolism of proteins 1715 3.50e-01 0.013600 4.93e-01
ABC transporters in lipid homeostasis 14 3.51e-01 -0.144000 4.96e-01
Transcriptional Regulation by TP53 351 3.52e-01 -0.028900 4.96e-01
Peptide hormone metabolism 51 3.52e-01 0.075300 4.96e-01
Disorders of transmembrane transporters 147 3.53e-01 0.044400 4.96e-01
Regulation of PTEN gene transcription 59 3.54e-01 0.069800 4.97e-01
RUNX2 regulates osteoblast differentiation 18 3.56e-01 0.126000 5.00e-01
O-glycosylation of TSR domain-containing proteins 27 3.57e-01 -0.102000 5.01e-01
Phase 4 - resting membrane potential 10 3.60e-01 0.167000 5.05e-01
RNA Polymerase I Promoter Escape 47 3.62e-01 -0.076900 5.06e-01
Deadenylation of mRNA 22 3.63e-01 -0.112000 5.08e-01
Biological oxidations 136 3.64e-01 0.045100 5.08e-01
NCAM signaling for neurite out-growth 43 3.65e-01 -0.079900 5.08e-01
DAP12 signaling 28 3.65e-01 0.098900 5.08e-01
Synthesis of substrates in N-glycan biosythesis 58 3.66e-01 0.068700 5.08e-01
Voltage gated Potassium channels 25 3.66e-01 0.105000 5.08e-01
Protein methylation 15 3.66e-01 -0.135000 5.08e-01
Synthesis, secretion, and deacylation of Ghrelin 12 3.67e-01 -0.150000 5.09e-01
Signaling by FGFR3 in disease 13 3.69e-01 -0.144000 5.11e-01
Signaling by FGFR3 point mutants in cancer 13 3.69e-01 -0.144000 5.11e-01
Metabolism of Angiotensinogen to Angiotensins 11 3.71e-01 0.156000 5.13e-01
Signaling by Activin 10 3.72e-01 -0.163000 5.14e-01
Chromatin modifying enzymes 217 3.72e-01 0.035100 5.14e-01
Chromatin organization 217 3.72e-01 0.035100 5.14e-01
Negative regulation of NMDA receptor-mediated neuronal transmission 14 3.73e-01 -0.137000 5.14e-01
DDX58/IFIH1-mediated induction of interferon-alpha/beta 63 3.74e-01 0.064700 5.15e-01
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 11 3.77e-01 -0.154000 5.19e-01
Negative epigenetic regulation of rRNA expression 65 3.78e-01 -0.063200 5.19e-01
VEGFR2 mediated cell proliferation 18 3.79e-01 0.120000 5.20e-01
Regulation of RUNX2 expression and activity 66 3.79e-01 0.062600 5.20e-01
Defective B3GALT6 causes EDSP2 and SEMDJL1 11 3.80e-01 -0.153000 5.20e-01
Caspase-mediated cleavage of cytoskeletal proteins 12 3.81e-01 0.146000 5.21e-01
Cellular responses to external stimuli 505 3.81e-01 -0.022800 5.21e-01
Regulation of TP53 Expression and Degradation 36 3.86e-01 -0.083500 5.27e-01
SCF(Skp2)-mediated degradation of p27/p21 60 3.87e-01 0.064600 5.27e-01
Regulation of FOXO transcriptional activity by acetylation 10 3.87e-01 0.158000 5.28e-01
Transport of inorganic cations/anions and amino acids/oligopeptides 79 3.89e-01 0.056100 5.29e-01
Establishment of Sister Chromatid Cohesion 11 3.89e-01 -0.150000 5.29e-01
Signaling by EGFR in Cancer 23 3.89e-01 0.104000 5.29e-01
SHC-mediated cascade:FGFR2 12 3.93e-01 -0.142000 5.33e-01
G1/S DNA Damage Checkpoints 65 3.94e-01 0.061100 5.34e-01
Signaling by ERBB2 44 3.95e-01 0.074200 5.34e-01
Autodegradation of Cdh1 by Cdh1:APC/C 64 3.95e-01 0.061500 5.34e-01
Pyruvate metabolism and Citric Acid (TCA) cycle 52 3.97e-01 0.068000 5.36e-01
Signaling by PDGFR in disease 19 3.98e-01 0.112000 5.37e-01
Infectious disease 723 3.99e-01 -0.018400 5.38e-01
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion 14 4.03e-01 0.129000 5.42e-01
Late Phase of HIV Life Cycle 131 4.03e-01 -0.042300 5.43e-01
Defective B4GALT7 causes EDS, progeroid type 11 4.03e-01 -0.145000 5.43e-01
Metal ion SLC transporters 21 4.05e-01 0.105000 5.44e-01
Depolymerisation of the Nuclear Lamina 15 4.05e-01 0.124000 5.44e-01
WNT ligand biogenesis and trafficking 21 4.07e-01 0.105000 5.45e-01
SIRT1 negatively regulates rRNA expression 24 4.07e-01 0.097700 5.46e-01
CDK-mediated phosphorylation and removal of Cdc6 71 4.11e-01 0.056500 5.49e-01
Other interleukin signaling 18 4.13e-01 0.111000 5.52e-01
Response of EIF2AK1 (HRI) to heme deficiency 14 4.15e-01 0.126000 5.54e-01
Class I peroxisomal membrane protein import 20 4.17e-01 -0.105000 5.56e-01
Acetylcholine Neurotransmitter Release Cycle 11 4.21e-01 -0.140000 5.61e-01
HCMV Infection 96 4.23e-01 0.047300 5.64e-01
Nuclear signaling by ERBB4 24 4.25e-01 0.094200 5.65e-01
cGMP effects 13 4.25e-01 0.128000 5.65e-01
CRMPs in Sema3A signaling 14 4.26e-01 0.123000 5.66e-01
Negative regulation of FGFR2 signaling 23 4.26e-01 0.095800 5.66e-01
Neurotransmitter release cycle 39 4.27e-01 0.073500 5.66e-01
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 16 4.30e-01 0.114000 5.69e-01
mRNA Capping 29 4.31e-01 -0.084600 5.69e-01
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 124 4.32e-01 -0.040800 5.71e-01
TNFR1-induced proapoptotic signaling 12 4.32e-01 -0.131000 5.71e-01
Glycolysis 67 4.33e-01 0.055300 5.72e-01
Unblocking of NMDA receptors, glutamate binding and activation 12 4.36e-01 -0.130000 5.74e-01
PECAM1 interactions 12 4.39e-01 0.129000 5.77e-01
GP1b-IX-V activation signalling 10 4.42e-01 0.140000 5.81e-01
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression 32 4.43e-01 0.078400 5.81e-01
Synthesis of PIPs at the early endosome membrane 16 4.44e-01 0.110000 5.83e-01
Resolution of D-Loop Structures 33 4.44e-01 -0.076900 5.83e-01
Estrogen-dependent nuclear events downstream of ESR-membrane signaling 22 4.45e-01 0.094000 5.83e-01
Loss of Nlp from mitotic centrosomes 69 4.46e-01 -0.053100 5.83e-01
Loss of proteins required for interphase microtubule organization from the centrosome 69 4.46e-01 -0.053100 5.83e-01
Lysine catabolism 11 4.47e-01 0.132000 5.83e-01
Phase II - Conjugation of compounds 68 4.47e-01 0.053300 5.83e-01
HATs acetylate histones 93 4.47e-01 -0.045600 5.83e-01
Signalling to RAS 19 4.48e-01 0.101000 5.83e-01
Acyl chain remodelling of PG 11 4.49e-01 0.132000 5.84e-01
Regulation of innate immune responses to cytosolic DNA 14 4.51e-01 -0.116000 5.85e-01
Regulation of TP53 Degradation 35 4.51e-01 -0.073700 5.85e-01
Aberrant regulation of mitotic exit in cancer due to RB1 defects 20 4.51e-01 -0.097300 5.85e-01
Mitotic Prophase 98 4.52e-01 0.044000 5.85e-01
CDC6 association with the ORC:origin complex 11 4.53e-01 -0.131000 5.86e-01
Regulation of TNFR1 signaling 32 4.53e-01 -0.076600 5.86e-01
Xenobiotics 11 4.56e-01 -0.130000 5.90e-01
The canonical retinoid cycle in rods (twilight vision) 10 4.57e-01 0.136000 5.91e-01
NOTCH2 Activation and Transmission of Signal to the Nucleus 20 4.60e-01 0.095500 5.93e-01
Alpha-protein kinase 1 signaling pathway 11 4.62e-01 0.128000 5.96e-01
Biosynthesis of DHA-derived SPMs 14 4.63e-01 0.113000 5.97e-01
Ras activation upon Ca2+ influx through NMDA receptor 15 4.70e-01 -0.108000 6.04e-01
Repression of WNT target genes 14 4.70e-01 -0.112000 6.04e-01
B-WICH complex positively regulates rRNA expression 47 4.71e-01 -0.060800 6.05e-01
Degradation of cysteine and homocysteine 12 4.73e-01 0.120000 6.07e-01
Negative regulators of DDX58/IFIH1 signaling 34 4.75e-01 -0.070700 6.09e-01
Tryptophan catabolism 12 4.76e-01 0.119000 6.09e-01
Nephrin family interactions 17 4.76e-01 -0.099800 6.09e-01
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75 4.77e-01 0.047500 6.09e-01
PRC2 methylates histones and DNA 29 4.83e-01 0.075200 6.17e-01
Collagen chain trimerization 27 4.85e-01 -0.077600 6.19e-01
Cargo trafficking to the periciliary membrane 47 4.86e-01 -0.058700 6.19e-01
Branched-chain amino acid catabolism 21 4.86e-01 -0.087700 6.19e-01
FRS-mediated FGFR2 signaling 14 4.87e-01 -0.107000 6.19e-01
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 36 4.88e-01 0.066800 6.20e-01
Purine catabolism 16 4.92e-01 -0.099200 6.25e-01
Signaling by FGFR2 IIIa TM 18 4.93e-01 -0.093400 6.25e-01
Defective B3GALTL causes Peters-plus syndrome (PpS) 26 4.94e-01 -0.077400 6.26e-01
Metabolism of cofactors 19 4.95e-01 0.090500 6.26e-01
Cellular hexose transport 15 4.97e-01 -0.101000 6.28e-01
PKA-mediated phosphorylation of CREB 17 4.98e-01 0.095000 6.28e-01
Pyruvate metabolism 28 4.98e-01 0.074100 6.28e-01
Methylation 12 4.99e-01 -0.113000 6.29e-01
Orc1 removal from chromatin 69 4.99e-01 -0.047100 6.29e-01
Elevation of cytosolic Ca2+ levels 12 5.00e-01 0.112000 6.30e-01
Synthesis of very long-chain fatty acyl-CoAs 21 5.04e-01 0.084200 6.34e-01
Defective B3GAT3 causes JDSSDHD 11 5.05e-01 -0.116000 6.35e-01
RAF-independent MAPK1/3 activation 21 5.09e-01 0.083200 6.39e-01
Activation of SMO 13 5.09e-01 0.106000 6.39e-01
TP53 Regulates Transcription of Caspase Activators and Caspases 11 5.10e-01 -0.115000 6.39e-01
SLC transporter disorders 77 5.13e-01 -0.043100 6.42e-01
Laminin interactions 21 5.15e-01 0.082000 6.45e-01
Ion homeostasis 40 5.18e-01 0.059000 6.48e-01
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 43 5.21e-01 0.056500 6.51e-01
Downstream signaling of activated FGFR2 19 5.22e-01 -0.084800 6.51e-01
Signaling by NTRK2 (TRKB) 20 5.23e-01 0.082500 6.52e-01
Hedgehog 'off' state 92 5.28e-01 0.038100 6.57e-01
NF-kB is activated and signals survival 12 5.30e-01 0.105000 6.58e-01
APC/C:Cdc20 mediated degradation of mitotic proteins 74 5.30e-01 0.042200 6.58e-01
p75NTR signals via NF-kB 15 5.31e-01 0.093500 6.58e-01
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects 17 5.31e-01 0.087800 6.58e-01
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) 17 5.31e-01 0.087800 6.58e-01
Anti-inflammatory response favouring Leishmania parasite infection 169 5.34e-01 -0.027700 6.61e-01
Leishmania parasite growth and survival 169 5.34e-01 -0.027700 6.61e-01
Termination of O-glycan biosynthesis 16 5.39e-01 0.088700 6.66e-01
Processing and activation of SUMO 10 5.39e-01 -0.112000 6.66e-01
TNFR2 non-canonical NF-kB pathway 95 5.43e-01 -0.036100 6.70e-01
Respiratory electron transport 101 5.48e-01 -0.034600 6.76e-01
Receptor Mediated Mitophagy 11 5.49e-01 0.104000 6.76e-01
Heme biosynthesis 14 5.51e-01 0.091900 6.79e-01
Acyl chain remodelling of PE 20 5.54e-01 0.076400 6.82e-01
Formation of RNA Pol II elongation complex 57 5.58e-01 0.044900 6.84e-01
RNA Polymerase II Transcription Elongation 57 5.58e-01 0.044900 6.84e-01
CDT1 association with the CDC6:ORC:origin complex 57 5.58e-01 0.044800 6.84e-01
Transcriptional regulation by small RNAs 63 5.62e-01 -0.042300 6.88e-01
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72 5.65e-01 0.039200 6.92e-01
Basigin interactions 23 5.68e-01 -0.068800 6.94e-01
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 18 5.69e-01 0.077500 6.94e-01
Signaling by Ligand-Responsive EGFR Variants in Cancer 18 5.69e-01 0.077500 6.94e-01
O-linked glycosylation 84 5.69e-01 0.035900 6.94e-01
Competing endogenous RNAs (ceRNAs) regulate PTEN translation 11 5.75e-01 0.097600 7.01e-01
FRS-mediated FGFR1 signaling 14 5.77e-01 0.086100 7.02e-01
SUMOylation of transcription factors 16 5.79e-01 0.080200 7.04e-01
Regulation of necroptotic cell death 14 5.80e-01 -0.085400 7.05e-01
Mitotic Telophase/Cytokinesis 13 5.83e-01 0.088000 7.08e-01
MicroRNA (miRNA) biogenesis 24 5.85e-01 -0.064400 7.09e-01
AURKA Activation by TPX2 72 5.90e-01 -0.036700 7.15e-01
TP53 Regulates Transcription of Cell Cycle Genes 48 5.90e-01 -0.044900 7.15e-01
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation 10 5.93e-01 -0.097500 7.17e-01
Pexophagy 11 5.94e-01 0.092800 7.17e-01
MASTL Facilitates Mitotic Progression 10 5.95e-01 0.097100 7.17e-01
Defective EXT1 causes exostoses 1, TRPS2 and CHDS 10 5.95e-01 -0.097000 7.17e-01
Defective EXT2 causes exostoses 2 10 5.95e-01 -0.097000 7.17e-01
Zinc transporters 14 5.95e-01 0.082000 7.17e-01
Regulation of PTEN mRNA translation 13 5.96e-01 0.084800 7.18e-01
DCC mediated attractive signaling 13 6.00e-01 -0.084000 7.22e-01
RMTs methylate histone arginines 37 6.02e-01 -0.049600 7.23e-01
Downregulation of SMAD2/3:SMAD4 transcriptional activity 23 6.04e-01 0.062500 7.25e-01
Cell surface interactions at the vascular wall 174 6.11e-01 -0.022400 7.32e-01
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 18 6.11e-01 -0.069200 7.32e-01
Molecules associated with elastic fibres 22 6.12e-01 0.062500 7.32e-01
Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71 6.13e-01 0.034800 7.33e-01
Transcriptional activation of mitochondrial biogenesis 51 6.13e-01 0.040900 7.33e-01
SHC-mediated cascade:FGFR1 12 6.18e-01 0.083200 7.37e-01
Visual phototransduction 59 6.18e-01 0.037600 7.37e-01
Condensation of Prometaphase Chromosomes 11 6.18e-01 0.086800 7.37e-01
Nonhomologous End-Joining (NHEJ) 42 6.21e-01 0.044100 7.39e-01
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 23 6.21e-01 0.059500 7.39e-01
Endosomal/Vacuolar pathway 12 6.22e-01 -0.082100 7.39e-01
Transcription of the HIV genome 67 6.23e-01 -0.034800 7.39e-01
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 21 6.24e-01 0.061900 7.40e-01
PI-3K cascade:FGFR4 10 6.25e-01 -0.089200 7.41e-01
CD28 dependent Vav1 pathway 12 6.27e-01 0.081100 7.42e-01
Nicotinamide salvaging 14 6.31e-01 0.074200 7.46e-01
Pregnenolone biosynthesis 10 6.36e-01 0.086500 7.52e-01
Chondroitin sulfate/dermatan sulfate metabolism 38 6.42e-01 0.043500 7.58e-01
NRIF signals cell death from the nucleus 15 6.43e-01 0.069200 7.58e-01
CLEC7A (Dectin-1) induces NFAT activation 11 6.46e-01 -0.080100 7.61e-01
Interleukin-2 signaling 11 6.49e-01 0.079200 7.65e-01
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 31 6.51e-01 -0.047000 7.66e-01
Post NMDA receptor activation events 48 6.51e-01 0.037700 7.66e-01
RNA Pol II CTD phosphorylation and interaction with CE 27 6.52e-01 -0.050100 7.66e-01
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 27 6.52e-01 -0.050100 7.66e-01
Synthesis of PE 12 6.53e-01 -0.075000 7.66e-01
Neurexins and neuroligins 37 6.56e-01 -0.042300 7.69e-01
TP53 Regulates Transcription of Cell Death Genes 42 6.57e-01 0.039600 7.69e-01
Prefoldin mediated transfer of substrate to CCT/TriC 26 6.59e-01 -0.050000 7.70e-01
RAS processing 19 6.60e-01 -0.058400 7.70e-01
NoRC negatively regulates rRNA expression 62 6.60e-01 -0.032300 7.70e-01
GABA synthesis, release, reuptake and degradation 13 6.61e-01 -0.070300 7.70e-01
Downstream signaling of activated FGFR1 20 6.61e-01 0.056700 7.70e-01
Eicosanoid ligand-binding receptors 13 6.61e-01 -0.070200 7.70e-01
Netrin-1 signaling 40 6.61e-01 0.040000 7.70e-01
TRP channels 17 6.63e-01 0.061000 7.71e-01
Interleukin-7 signaling 21 6.64e-01 0.054800 7.71e-01
Diseases associated with O-glycosylation of proteins 49 6.67e-01 -0.035500 7.75e-01
Inhibition of replication initiation of damaged DNA by RB1/E2F1 13 6.70e-01 -0.068200 7.76e-01
Aflatoxin activation and detoxification 14 6.70e-01 0.065700 7.76e-01
Ephrin signaling 17 6.72e-01 0.059300 7.76e-01
Sema3A PAK dependent Axon repulsion 16 6.73e-01 0.060900 7.76e-01
HIV elongation arrest and recovery 32 6.73e-01 0.043100 7.76e-01
Pausing and recovery of HIV elongation 32 6.73e-01 0.043100 7.76e-01
Cyclin D associated events in G1 47 6.73e-01 0.035500 7.76e-01
G1 Phase 47 6.73e-01 0.035500 7.76e-01
Activation of RAC1 11 6.74e-01 0.073200 7.76e-01
Signaling by FGFR 69 6.74e-01 0.029300 7.76e-01
p75NTR recruits signalling complexes 12 6.77e-01 0.069400 7.79e-01
Mitochondrial Fatty Acid Beta-Oxidation 36 6.80e-01 -0.039700 7.82e-01
ERBB2 Regulates Cell Motility 10 6.82e-01 0.074900 7.83e-01
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 46 6.84e-01 0.034700 7.85e-01
Synthesis of glycosylphosphatidylinositol (GPI) 17 6.84e-01 -0.057000 7.85e-01
Diseases associated with glycosaminoglycan metabolism 26 6.86e-01 0.045800 7.86e-01
Gamma carboxylation, hypusine formation and arylsulfatase activation 34 6.89e-01 -0.039700 7.89e-01
Signaling by FGFR in disease 51 6.94e-01 0.031900 7.93e-01
The citric acid (TCA) cycle and respiratory electron transport 172 6.94e-01 -0.017400 7.93e-01
HIV Transcription Initiation 45 6.99e-01 -0.033300 7.93e-01
RNA Polymerase II HIV Promoter Escape 45 6.99e-01 -0.033300 7.93e-01
RNA Polymerase II Promoter Escape 45 6.99e-01 -0.033300 7.93e-01
RNA Polymerase II Transcription Initiation 45 6.99e-01 -0.033300 7.93e-01
RNA Polymerase II Transcription Initiation And Promoter Clearance 45 6.99e-01 -0.033300 7.93e-01
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 45 6.99e-01 -0.033300 7.93e-01
Formation of HIV-1 elongation complex containing HIV-1 Tat 42 6.99e-01 -0.034500 7.93e-01
HIV Transcription Elongation 42 6.99e-01 -0.034500 7.93e-01
Tat-mediated elongation of the HIV-1 transcript 42 6.99e-01 -0.034500 7.93e-01
IGF1R signaling cascade 36 7.01e-01 0.037000 7.94e-01
Signaling by BMP 21 7.03e-01 -0.048000 7.96e-01
Transcriptional Regulation by VENTX 38 7.04e-01 -0.035600 7.96e-01
Polo-like kinase mediated events 16 7.05e-01 0.054700 7.97e-01
SHC1 events in ERBB4 signaling 10 7.06e-01 0.068800 7.97e-01
Aberrant regulation of mitotic cell cycle due to RB1 defects 36 7.07e-01 -0.036200 7.97e-01
Diseases of mitotic cell cycle 36 7.07e-01 -0.036200 7.97e-01
Nuclear Envelope (NE) Reassembly 69 7.08e-01 0.026100 7.98e-01
Complex I biogenesis 55 7.09e-01 -0.029100 7.98e-01
Metabolism of folate and pterines 16 7.13e-01 0.053100 8.02e-01
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein 73 7.22e-01 0.024100 8.11e-01
TICAM1,TRAF6-dependent induction of TAK1 complex 11 7.23e-01 0.061700 8.12e-01
Cyclin A/B1/B2 associated events during G2/M transition 25 7.30e-01 0.039800 8.20e-01
Formation of the Early Elongation Complex 33 7.34e-01 -0.034200 8.22e-01
Formation of the HIV-1 Early Elongation Complex 33 7.34e-01 -0.034200 8.22e-01
Phase 2 - plateau phase 18 7.35e-01 0.046100 8.23e-01
Processing of Intronless Pre-mRNAs 19 7.36e-01 -0.044700 8.23e-01
Mitotic Anaphase 223 7.37e-01 0.013100 8.23e-01
mitochondrial fatty acid beta-oxidation of saturated fatty acids 11 7.40e-01 -0.057800 8.26e-01
Diseases associated with N-glycosylation of proteins 17 7.42e-01 -0.046200 8.27e-01
DNA Double Strand Break Response 47 7.43e-01 0.027700 8.27e-01
Signaling by FGFR4 in disease 11 7.43e-01 -0.057100 8.27e-01
Interferon alpha/beta signaling 57 7.47e-01 0.024700 8.31e-01
Diseases of glycosylation 109 7.47e-01 0.017900 8.31e-01
Fc epsilon receptor (FCERI) signaling 190 7.48e-01 -0.013500 8.31e-01
Separation of Sister Chromatids 167 7.49e-01 -0.014400 8.31e-01
Metabolism of nitric oxide: NOS3 activation and regulation 12 7.51e-01 0.052900 8.33e-01
Amino acid transport across the plasma membrane 23 7.54e-01 0.037700 8.36e-01
Dopamine Neurotransmitter Release Cycle 20 7.55e-01 -0.040400 8.36e-01
Signaling by NODAL 13 7.59e-01 -0.049200 8.39e-01
Interferon gamma signaling 83 7.59e-01 -0.019400 8.39e-01
RNA Polymerase II Pre-transcription Events 78 7.60e-01 0.020000 8.39e-01
Downregulation of TGF-beta receptor signaling 26 7.65e-01 0.033900 8.44e-01
Keratan sulfate biosynthesis 22 7.65e-01 0.036700 8.44e-01
Signaling by ERBB2 ECD mutants 15 7.68e-01 0.044000 8.46e-01
Prolactin receptor signaling 11 7.68e-01 -0.051300 8.46e-01
Constitutive Signaling by NOTCH1 HD Domain Mutants 14 7.71e-01 0.044900 8.48e-01
Signaling by NOTCH1 HD Domain Mutants in Cancer 14 7.71e-01 0.044900 8.48e-01
Nitric oxide stimulates guanylate cyclase 16 7.72e-01 0.041900 8.48e-01
PKMTs methylate histone lysines 44 7.72e-01 -0.025200 8.48e-01
M Phase 360 7.73e-01 0.008860 8.48e-01
N-glycan antennae elongation in the medial/trans-Golgi 21 7.75e-01 0.036000 8.49e-01
Meiotic recombination 38 7.76e-01 0.026700 8.49e-01
Protein-protein interactions at synapses 57 7.76e-01 0.021800 8.49e-01
RIPK1-mediated regulated necrosis 16 7.79e-01 0.040600 8.50e-01
Regulated Necrosis 16 7.79e-01 0.040600 8.50e-01
Downregulation of ERBB2:ERBB3 signaling 12 7.81e-01 -0.046400 8.52e-01
Signaling by FGFR2 60 7.84e-01 -0.020400 8.55e-01
Maturation of nucleoprotein 10 7.86e-01 0.049500 8.57e-01
PI-3K cascade:FGFR1 12 7.88e-01 0.044900 8.58e-01
Constitutive Signaling by Aberrant PI3K in Cancer 54 7.97e-01 -0.020300 8.66e-01
Pausing and recovery of Tat-mediated HIV elongation 30 7.97e-01 0.027100 8.66e-01
Tat-mediated HIV elongation arrest and recovery 30 7.97e-01 0.027100 8.66e-01
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 18 7.98e-01 0.034900 8.66e-01
Interleukin-35 Signalling 12 8.12e-01 -0.039600 8.80e-01
Activation of BH3-only proteins 29 8.13e-01 0.025400 8.80e-01
SHC-mediated cascade:FGFR4 10 8.13e-01 -0.043200 8.80e-01
Activation of NMDA receptors and postsynaptic events 58 8.13e-01 0.017900 8.80e-01
Cytosolic sensors of pathogen-associated DNA 62 8.16e-01 -0.017100 8.82e-01
TP53 Regulates Transcription of Death Receptors and Ligands 11 8.16e-01 -0.040500 8.82e-01
Formation of HIV elongation complex in the absence of HIV Tat 44 8.18e-01 -0.020100 8.82e-01
Chaperone Mediated Autophagy 20 8.19e-01 -0.029600 8.83e-01
Mitotic Metaphase and Anaphase 224 8.20e-01 0.008840 8.83e-01
Purine salvage 12 8.21e-01 0.037800 8.84e-01
HIV Infection 224 8.23e-01 -0.008660 8.86e-01
Cyclin E associated events during G1/S transition 83 8.25e-01 0.014000 8.86e-01
Signaling by Retinoic Acid 31 8.25e-01 -0.022900 8.86e-01
Formation of ATP by chemiosmotic coupling 18 8.29e-01 0.029500 8.89e-01
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 24 8.29e-01 0.025400 8.89e-01
Glutamate Neurotransmitter Release Cycle 20 8.30e-01 -0.027700 8.89e-01
Glutathione synthesis and recycling 10 8.39e-01 -0.037100 8.99e-01
Synthesis of PA 32 8.44e-01 0.020100 9.03e-01
Acyl chain remodelling of PS 14 8.46e-01 0.030000 9.03e-01
Blood group systems biosynthesis 17 8.47e-01 0.027100 9.03e-01
CASP8 activity is inhibited 11 8.47e-01 -0.033500 9.03e-01
Dimerization of procaspase-8 11 8.47e-01 -0.033500 9.03e-01
Regulation by c-FLIP 11 8.47e-01 -0.033500 9.03e-01
IRAK2 mediated activation of TAK1 complex 10 8.51e-01 0.034400 9.06e-01
Nef mediated downregulation of MHC class I complex cell surface expression 10 8.52e-01 -0.034000 9.07e-01
PI3K events in ERBB2 signaling 11 8.53e-01 -0.032300 9.07e-01
Metabolism of water-soluble vitamins and cofactors 109 8.54e-01 0.010200 9.08e-01
HS-GAG degradation 16 8.55e-01 0.026300 9.08e-01
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 13 8.56e-01 -0.029000 9.08e-01
Signaling by ERBB2 TMD/JMD mutants 17 8.57e-01 -0.025200 9.08e-01
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 37 8.57e-01 0.017100 9.08e-01
Mitochondrial iron-sulfur cluster biogenesis 13 8.59e-01 -0.028500 9.08e-01
Lewis blood group biosynthesis 13 8.59e-01 0.028500 9.08e-01
Syndecan interactions 19 8.60e-01 0.023300 9.09e-01
GRB2 events in ERBB2 signaling 11 8.61e-01 -0.030600 9.09e-01
Sulfur amino acid metabolism 23 8.61e-01 0.021000 9.09e-01
Phase 0 - rapid depolarisation 28 8.64e-01 -0.018700 9.11e-01
Meiosis 68 8.65e-01 -0.011900 9.11e-01
Serotonin Neurotransmitter Release Cycle 15 8.67e-01 0.025000 9.13e-01
MECP2 regulates neuronal receptors and channels 13 8.68e-01 0.026600 9.13e-01
Signaling by ERBB2 KD Mutants 20 8.69e-01 -0.021400 9.13e-01
Selective autophagy 58 8.71e-01 -0.012400 9.14e-01
Fertilization 12 8.77e-01 0.025800 9.20e-01
APC/C-mediated degradation of cell cycle proteins 86 8.79e-01 0.009490 9.21e-01
Regulation of mitotic cell cycle 86 8.79e-01 0.009490 9.21e-01
Formation of tubulin folding intermediates by CCT/TriC 22 8.80e-01 0.018600 9.21e-01
IRS-related events triggered by IGF1R 35 8.82e-01 0.014500 9.22e-01
Antimicrobial peptides 33 8.83e-01 0.014900 9.23e-01
G2/M Transition 180 8.88e-01 -0.006060 9.28e-01
Downstream signaling of activated FGFR4 17 8.89e-01 -0.019600 9.28e-01
TNF signaling 42 8.92e-01 0.012200 9.30e-01
FRS-mediated FGFR3 signaling 11 8.94e-01 0.023200 9.31e-01
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) 12 8.95e-01 -0.022000 9.31e-01
Axon guidance 455 8.96e-01 -0.003570 9.31e-01
Glucagon-type ligand receptors 20 8.96e-01 0.016800 9.31e-01
Aggrephagy 22 8.97e-01 0.016000 9.31e-01
Mitochondrial biogenesis 88 8.97e-01 -0.008020 9.31e-01
Miscellaneous transport and binding events 20 8.99e-01 0.016400 9.33e-01
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) 10 9.05e-01 0.021700 9.38e-01
Regulation of RUNX1 Expression and Activity 18 9.09e-01 0.015600 9.41e-01
FRS-mediated FGFR4 signaling 12 9.10e-01 -0.018800 9.42e-01
Cell-cell junction organization 38 9.11e-01 0.010500 9.42e-01
FOXO-mediated transcription of cell cycle genes 15 9.14e-01 -0.016200 9.43e-01
Signaling by NTRK3 (TRKC) 16 9.14e-01 -0.015600 9.43e-01
STING mediated induction of host immune responses 15 9.14e-01 -0.016000 9.43e-01
Downregulation of ERBB2 signaling 24 9.19e-01 -0.011900 9.47e-01
N-Glycan antennae elongation 13 9.20e-01 0.016000 9.47e-01
Class C/3 (Metabotropic glutamate/pheromone receptors) 12 9.20e-01 -0.016700 9.47e-01
Assembly of the pre-replicative complex 66 9.21e-01 0.007080 9.47e-01
MET activates PTK2 signaling 15 9.22e-01 0.014600 9.48e-01
Reproduction 80 9.23e-01 -0.006240 9.48e-01
Cyclin A:Cdk2-associated events at S phase entry 85 9.24e-01 0.005970 9.49e-01
RHO GTPases Activate Formins 117 9.27e-01 0.004880 9.51e-01
Signaling by ERBB2 in Cancer 21 9.32e-01 0.010800 9.55e-01
CTLA4 inhibitory signaling 21 9.34e-01 0.010500 9.56e-01
Norepinephrine Neurotransmitter Release Cycle 14 9.44e-01 -0.010800 9.66e-01
Deactivation of the beta-catenin transactivating complex 36 9.46e-01 0.006500 9.67e-01
Non-integrin membrane-ECM interactions 37 9.46e-01 0.006400 9.67e-01
Downstream signaling of activated FGFR3 16 9.49e-01 0.009200 9.68e-01
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 29 9.49e-01 0.006810 9.68e-01
Receptor-type tyrosine-protein phosphatases 12 9.50e-01 0.010500 9.68e-01
Lysosphingolipid and LPA receptors 11 9.56e-01 -0.009620 9.74e-01
Attenuation phase 23 9.58e-01 0.006360 9.75e-01
HSF1-dependent transactivation 29 9.59e-01 -0.005520 9.75e-01
IL-6-type cytokine receptor ligand interactions 12 9.61e-01 0.008150 9.77e-01
Kinesins 39 9.64e-01 0.004220 9.79e-01
Interaction between L1 and Ankyrins 22 9.65e-01 0.005380 9.80e-01
Cohesin Loading onto Chromatin 10 9.67e-01 0.007580 9.81e-01
TICAM1-dependent activation of IRF3/IRF7 12 9.69e-01 -0.006580 9.81e-01
Mitotic G2-G2/M phases 182 9.70e-01 0.001630 9.82e-01
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14 9.70e-01 -0.005800 9.82e-01
SUMOylation of transcription cofactors 44 9.72e-01 0.003100 9.82e-01
Signaling by KIT in disease 20 9.74e-01 0.004280 9.82e-01
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants 20 9.74e-01 0.004280 9.82e-01
TNFR1-induced NFkappaB signaling pathway 25 9.74e-01 -0.003800 9.82e-01
CD28 co-stimulation 33 9.77e-01 -0.002840 9.85e-01
PI3K Cascade 30 9.78e-01 -0.002900 9.85e-01
Regulation of APC/C activators between G1/S and early anaphase 79 9.80e-01 -0.001670 9.85e-01
Nervous system development 474 9.80e-01 0.000685 9.85e-01
IRS-mediated signalling 34 9.83e-01 -0.002090 9.88e-01
Association of TriC/CCT with target proteins during biosynthesis 37 9.90e-01 -0.001170 9.93e-01
Abortive elongation of HIV-1 transcript in the absence of Tat 23 9.90e-01 0.001450 9.93e-01
Nuclear Receptor transcription pathway 36 9.90e-01 0.001150 9.93e-01
Regulation of pyruvate dehydrogenase (PDH) complex 15 9.95e-01 -0.000919 9.97e-01
Nucleotide-like (purinergic) receptors 12 9.96e-01 0.000917 9.97e-01
Incretin synthesis, secretion, and inactivation 10 9.99e-01 -0.000241 9.99e-01
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) 10 9.99e-01 -0.000241 9.99e-01


Detailed Gene set reports



Neutrophil degranulation

Neutrophil degranulation
734
set Neutrophil degranulation
setSize 458
pANOVA 3.16e-61
s.dist 0.449
p.adjustANOVA 4.3e-58



Top enriched genes

Top 20 genes
GeneID Gene Rank
SLC11A1 11464
NCSTN 11452
DOK3 11443
P2RX1 11442
LILRB2 11437
HK3 11430
OSCAR 11425
IDH1 11418
SIRPA 11414
GNS 11410
SERPINA1 11407
CR1 11401
DNASE1L1 11385
SIGLEC9 11381
QSOX1 11369
CD63 11355
MCEMP1 11349
FGR 11323
HP 11312
NCKAP1L 11304

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SLC11A1 11464
NCSTN 11452
DOK3 11443
P2RX1 11442
LILRB2 11437
HK3 11430
OSCAR 11425
IDH1 11418
SIRPA 11414
GNS 11410
SERPINA1 11407
CR1 11401
DNASE1L1 11385
SIGLEC9 11381
QSOX1 11369
CD63 11355
MCEMP1 11349
FGR 11323
HP 11312
NCKAP1L 11304
IMPDH1 11303
CTSD 11297
C3AR1 11294
ATP6V0A1 11283
LAIR1 11276
ITGAM 11269
UNC13D 11266
CTSB 11250
ITGAX 11231
ANPEP 11227
FPR1 11221
FCER1G 11216
TIMP2 11214
S100A12 11206
MAPK1 11193
RNASE2 11192
S100A8 11184
ALOX5 11178
GUSB 11175
PRKCD 11168
TCIRG1 11138
TRPM2 11134
PGAM1 11128
PLAC8 11120
MAPK14 11115
PLD1 11091
NEU1 11082
SERPINB1 11081
ACAA1 11076
CD177 11068
ALDH3B1 11063
C5AR1 11061
MMP25 11057
AGPAT2 11054
PLEKHO2 11053
ADGRG3 11019
VNN1 11000
GCA 10999
ATP6V0C 10995
VAT1 10971
BRI3 10962
RAB10 10956
PYGL 10952
MGAM 10950
CD36 10947
CD93 10937
MOSPD2 10933
CEACAM3 10932
MMP9 10920
CD55 10914
S100A11 10910
NFAM1 10890
FPR2 10883
GYG1 10873
ALDOA 10868
ITGB2 10861
CDA 10859
GM2A 10846
CTSA 10842
GRN 10837
CKAP4 10819
CRISPLD2 10814
ASAH1 10796
ATP11A 10791
LRG1 10785
CYB5R3 10775
TSPAN14 10759
NBEAL2 10743
RETN 10732
SLC2A3 10714
ANXA2 10704
QPCT 10700
SLC15A4 10684
RAB3D 10677
RAB31 10661
BST1 10647
RHOG 10635
GPR84 10632
RAC1 10624
S100A9 10613
CYSTM1 10605
GLA 10595
TOM1 10594
CAPN1 10570
GSN 10558
TNFAIP6 10555
CD68 10546
LTA4H 10541
PYCARD 10540
TLR2 10535
PKM 10523
IGF2R 10494
PLAUR 10490
FCGR2A 10470
ALAD 10449
PTPN6 10446
LILRB3 10433
PSEN1 10429
CYFIP1 10420
PECAM1 10414
CLEC4D 10398
PGM2 10380
DNAJC5 10371
CD300A 10362
PTPRJ 10340
COTL1 10333
CD53 10308
ACLY 10268
PADI2 10252
AP2A2 10223
FCAR 10219
GLB1 10217
TMBIM1 10197
PTAFR 10188
AMPD3 10183
CYBA 10173
DOCK2 10155
NAPRT 10133
RAB7A 10115
CAT 10103
ARPC5 10102
FTL 10101
TNFRSF1B 10079
ARG1 10061
ARL8A 10056
ARSB 10041
IQGAP1 10037
ADAM10 9992
CPPED1 9991
ATP6V1D 9982
SELL 9974
RAB6A 9958
SDCBP 9947
CTSZ 9943
CAP1 9934
DNAJC13 9921
S100P 9918
RAB5C 9864
MGST1 9847
DNAJC3 9831
DBNL 9815
BIN2 9720
LAMP1 9712
ARHGAP9 9702
CD58 9688
TOLLIP 9682
HSPA6 9675
CYBB 9660
TYROBP 9637
VAPA 9635
RAB24 9634
RAB27A 9628
AP1M1 9595
CSTB 9479
CD14 9466
GMFG 9443
RHOA 9401
CAB39 9379
DERA 9344
HSPA1A 9341
CXCR1 9335
VPS35L 9320
CTSC 9276
LAMTOR1 9265
CANT1 9259
CD44 9255
SIGLEC5 9235
LGALS3 9180
SNAP29 9157
CNN2 9140
TRAPPC1 9087
CEACAM1 9052
GALNS 9046
LAMP2 9034
PDAP1 9011
IST1 8994
STK10 8992
CMTM6 8960
ADAM8 8938
ADGRE5 8937
ACTR2 8895
PSAP 8894
MNDA 8892
CFP 8875
STK11IP 8872
HPSE 8832
APAF1 8822
HSPA1B 8806
MMP8 8706
ROCK1 8695
CREG1 8692
GAA 8625
MVP 8603
HEBP2 8559
ATP11B 8523
PRCP 8518
CLEC5A 8487
SLCO4C1 8486
DDOST 8464
PSMB7 8460
ARSA 8456
RAB4B 8449
TUBB4B 8440
IQGAP2 8437
KCMF1 8403
OSTF1 8338
SURF4 8306
DYNC1LI1 8276
PDXK 8267
RAB5B 8258
PSMD1 8184
PSMD2 8139
PNP 8043
PTPRC 8021
LAMTOR2 8006
COPB1 7997
STOM 7990
RNASET2 7961
FCN1 7954
FABP5 7903
ITGAV 7847
VCP 7804
PSMD11 7775
B4GALT1 7763
LPCAT1 7696
HEXB 7695
MANBA 7689
OLFM4 7638
RAP2C 7598
FAF2 7588
SNAP23 7530
RAP1A 7335
PSMD6 7307
YPEL5 7288
PGM1 7238
GGH 7233
COMMD9 7156
SIRPB1 7136
DIAPH1 7128
GPI 7117
CXCL1 7072
RAB18 7038
TMEM30A 7030
RAP1B 6962
GDI2 6949
CD33 6932
DYNLT1 6926
FTH1 6883
C6orf120 6840
PSMD12 6820
CXCR2 6720
METTL7A 6718
HBB 6697
UBR4 6594
CTSS 6504
FUCA1 6469
KCNAB2 6369
PIGR 6337
RAB3A 6284
VCL 6193
LRMP 6184
ATG7 6082
FUCA2 6028
PAFAH1B2 5996
NDUFC2 5943
ACTR10 5886
CSNK2B 5876
MAN2B1 5768
STBD1 5663
SIGLEC14 5662
SERPINB10 5629
KPNB1 5604
RAB14 5469
LAMTOR3 5383
SERPINB6 5280
ATP8B4 5252
SLC44A2 5180
DGAT1 5173
PRDX6 5085
SRP14 5022
NHLRC3 5010
CTSH 4985
APEH 4945
ATP6AP2 4915
PGLYRP1 4910
NRAS 4907
PTPRN2 4854
ERP44 4818
GLIPR1 4675
ARMC8 4598
PSMC2 4543
NFASC 4356
MAGT1 4339
PSMD3 4297
TICAM2 4262
CD59 4252
TARM1 3952
RAP2B 3915
PLAU 3907
PSMD13 3766
ITGAL 3647
ANO6 3404
NPC2 3326
DEGS1 3135
CPNE3 2985
HLA-C 2969
NFKB1 2860
FOLR3 2736
FRK 2672
AOC1 2506
CLEC12A 2330
LCN2 2300
CLEC4C 2219
CDK13 2118
PSMD7 2084
ORM1 2075
GHDC 1853
XRCC5 1832
CST3 1747
DYNC1H1 1705
DDX3X 1692
PTX3 1567
DYNLL1 1530
CRISP3 1416
FCGR3B 1391
ADGRE3 1240
HUWE1 1218
CRACR2A 1215
PSMD14 941
PSMC3 916
SYNGR1 852
MLEC 796
MME 695
ORM2 565
CFD 461
GSDMD 370
AGL 316
STING1 94
GOLGA7 14
PGRMC1 -59
HLA-B -98
VAMP8 -139
HVCN1 -250
ENPP4 -308
LRRC7 -340
RNASE3 -371
PYGB -418
FRMPD3 -550
DSP -573
HGSNAT -737
GSTP1 -759
BST2 -782
NME2 -791
PRDX4 -834
RAB37 -1057
LYZ -1067
A1BG -1468
CPNE1 -1632
TMEM179B -1671
TUBB -1675
TCN1 -1708
CHIT1 -1890
PPBP -1960
TXNDC5 -2141
COMMD3 -2657
JUP -2668
HLA-H -2741
CCT8 -2751
PSMA2 -2823
SVIP -3052
SLPI -3392
C3 -3394
RAB44 -3423
PFKL -3512
PSMB1 -3610
HSP90AA1 -4016
RAB9B -4177
PTPRB -4321
ILF2 -4378
LTF -4464
EPX -4781
HRNR -5086
PA2G4 -5255
KRT1 -5265
DSN1 -5307
BPI -5410
PTGES2 -5466
ALDOC -5613
CHI3L1 -5761
ACTR1B -5952
HLA-A -5985
DPP7 -6012
FGL2 -6015
ORMDL3 -6182
SLC27A2 -6278
EEF2 -6279
PPIE -6341
SLC2A5 -6479
PPIA -6498
TMC6 -6551
HMGB1 -6699
ABCA13 -6934
B2M -6943
MS4A3 -7001
CAND1 -7058
MIF -7102
SCAMP1 -7313
PSMA5 -7476
CEACAM8 -7546
APRT -7580
TBC1D10C -7608
OLR1 -7621
AGA -7674
DEFA1 -7680
DEFA4 -7723
TMEM63A -7978
XRCC6 -8146
CEP290 -8156
MPO -8263
CEACAM6 -8277
ATAD3B -8354
ELANE -8371
CAMP -8417
RHOF -8679
HMOX2 -8794
HSPA8 -9129
NIT2 -9152
CD47 -9164
HSP90AB1 -9172
ATP8A1 -9218
PRTN3 -9350
AZU1 -9380
SPTAN1 -9461
CTSG -9503
DSC1 -9630
EEF1A1 -9751
CCT2 -10024
IMPDH2 -10126


rRNA processing in the nucleus and cytosol

rRNA processing in the nucleus and cytosol
1353
set rRNA processing in the nucleus and cytosol
setSize 190
pANOVA 7.19e-52
s.dist -0.636
p.adjustANOVA 4.89e-49



Top enriched genes

Top 20 genes
GeneID Gene Rank
DKC1 -10139
RPP40 -10069
NOP58 -10031
RPL23A -9979
GNL3 -9960
RPL3 -9957
FBL -9942
NOL11 -9932
RPL5 -9881
RPS3A -9834
NAT10 -9828
WDR75 -9823
THUMPD1 -9782
RPL7 -9765
EXOSC2 -9753
TSR1 -9724
RPS27A -9723
UTP4 -9700
RPS6 -9699
RPL14 -9698

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DKC1 -10139
RPP40 -10069
NOP58 -10031
RPL23A -9979
GNL3 -9960
RPL3 -9957
FBL -9942
NOL11 -9932
RPL5 -9881
RPS3A -9834
NAT10 -9828
WDR75 -9823
THUMPD1 -9782
RPL7 -9765
EXOSC2 -9753
TSR1 -9724
RPS27A -9723
UTP4 -9700
RPS6 -9699
RPL14 -9698
LAS1L -9679
RPS25 -9664
RPL22 -9659
DIMT1 -9652
NOP14 -9641
BMS1 -9626
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
NOP56 -9444
RPS20 -9413
RPL13A -9402
WDR43 -9395
RPS23 -9387
EXOSC8 -9379
RPL32 -9345
NCL -9336
DDX47 -9334
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
UTP15 -9156
RPL11 -9117
RPL17 -9116
WDR46 -9056
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
TEX10 -8915
RPL36A -8909
NOB1 -8908
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
MPHOSPH10 -8840
EXOSC9 -8793
NOL9 -8786
RPL31 -8769
EMG1 -8744
RPS13 -8724
RPL26 -8706
RPP25 -8688
RPS4X -8648
RPP30 -8640
RPS29 -8637
RPL39 -8635
RPL29 -8621
UTP6 -8616
RRP9 -8598
RPS16 -8579
RPS14 -8541
SNU13 -8495
RPS10 -8494
EXOSC7 -8473
EXOSC5 -8394
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
NOP2 -8307
RPL7A -8286
RPS17 -8281
PELP1 -8232
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
RPS28 -8083
RIOK2 -8079
PNO1 -8004
RPS11 -7975
RPL38 -7968
EBNA1BP2 -7916
RPL37 -7861
NOL6 -7834
RPL27 -7810
RPS19 -7806
NIP7 -7779
KRR1 -7720
RCL1 -7690
RPP38 -7683
RPL13 -7671
DCAF13 -7564
RPL41 -7561
RPL36 -7493
EXOSC6 -7458
UTP20 -7427
GAR1 -7407
HEATR1 -7278
IMP4 -7155
PES1 -7148
LTV1 -7119
WDR3 -7016
IMP3 -6912
RPL37A -6833
EXOSC10 -6829
RPL9 -6821
RPS24 -6818
RPS15 -6703
RPL36AL -6646
RPSA -6629
BOP1 -6593
PDCD11 -6547
NHP2 -6535
CSNK1E -6526
RPL8 -6101
RPLP1 -6018
RBM28 -5712
PWP2 -5423
RRP7A -5246
WDR36 -5072
BYSL -4898
RIOK1 -4858
UTP3 -4821
DHX37 -4742
MTREX -4495
RPP21 -4260
DIS3 -4140
RPL28 -3873
WDR18 -3817
FAU -3618
UBA52 -3490
UTP14A -3323
MPHOSPH6 -3194
RRP1 -3051
UTP14C -2415
TRMT112 -2296
RPP14 -2204
RPL39L -1661
FTSJ3 -1199
DDX21 -1198
RPS26 -1154
WDR12 -731
RPS27L -496
EXOSC1 -493
RRP36 -395
C1D -325
EXOSC3 -40
UTP11 -37
SENP3 78
RPS4Y1 331
FCF1 453
TBL3 739
TSR3 1498
NOC4L 1606
DDX52 1795
RPS9 1841
ISG20L2 3150
UTP18 3850
DDX49 4083
NOL12 4277
RPL3L 5150
RPL26L1 6001
ERI1 6679
RIOK3 7088
CSNK1D 8475
EXOSC4 10040
XRN2 10267
NOP10 10379
SNORD3A 10596


rRNA processing

rRNA processing
1351
set rRNA processing
setSize 217
pANOVA 2.08e-51
s.dist -0.593
p.adjustANOVA 9.44e-49



Top enriched genes

Top 20 genes
GeneID Gene Rank
DKC1 -10139
RPP40 -10069
NOP58 -10031
RPL23A -9979
GNL3 -9960
RPL3 -9957
FBL -9942
NOL11 -9932
MTERF4 -9917
RPL5 -9881
RPS3A -9834
NAT10 -9828
WDR75 -9823
THUMPD1 -9782
RPL7 -9765
EXOSC2 -9753
TSR1 -9724
RPS27A -9723
UTP4 -9700
RPS6 -9699

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DKC1 -10139
RPP40 -10069
NOP58 -10031
RPL23A -9979
GNL3 -9960
RPL3 -9957
FBL -9942
NOL11 -9932
MTERF4 -9917
RPL5 -9881
RPS3A -9834
NAT10 -9828
WDR75 -9823
THUMPD1 -9782
RPL7 -9765
EXOSC2 -9753
TSR1 -9724
RPS27A -9723
UTP4 -9700
RPS6 -9699
RPL14 -9698
LAS1L -9679
RPS25 -9664
RPL22 -9659
DIMT1 -9652
NOP14 -9641
BMS1 -9626
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
NOP56 -9444
RPS20 -9413
RPL13A -9402
WDR43 -9395
RPS23 -9387
EXOSC8 -9379
RPL32 -9345
NCL -9336
DDX47 -9334
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
UTP15 -9156
RPL11 -9117
RPL17 -9116
WDR46 -9056
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
TEX10 -8915
RPL36A -8909
NOB1 -8908
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
MPHOSPH10 -8840
EXOSC9 -8793
NOL9 -8786
RPL31 -8769
EMG1 -8744
RPS13 -8724
RPL26 -8706
RPP25 -8688
RPS4X -8648
RPP30 -8640
RPS29 -8637
RPL39 -8635
RPL29 -8621
UTP6 -8616
RRP9 -8598
RPS16 -8579
RPS14 -8541
MRM1 -8526
SNU13 -8495
RPS10 -8494
EXOSC7 -8473
EXOSC5 -8394
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
NOP2 -8307
TRMT10C -8306
RPL7A -8286
RPS17 -8281
PELP1 -8232
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
RPS28 -8083
RIOK2 -8079
PNO1 -8004
RPS11 -7975
RPL38 -7968
EBNA1BP2 -7916
RPL37 -7861
NOL6 -7834
RPL27 -7810
RPS19 -7806
NIP7 -7779
KRR1 -7720
RCL1 -7690
RPP38 -7683
RPL13 -7671
DCAF13 -7564
RPL41 -7561
RPL36 -7493
EXOSC6 -7458
UTP20 -7427
GAR1 -7407
HEATR1 -7278
IMP4 -7155
PES1 -7148
LTV1 -7119
WDR3 -7016
IMP3 -6912
TFB1M -6859
RPL37A -6833
EXOSC10 -6829
RPL9 -6821
RPS24 -6818
RPS15 -6703
RPL36AL -6646
RPSA -6629
BOP1 -6593
PDCD11 -6547
NHP2 -6535
CSNK1E -6526
RPL8 -6101
MT-ND2 -6095
RPLP1 -6018
RBM28 -5712
MRM3 -5709
MT-ND3 -5522
PWP2 -5423
ELAC2 -5385
RRP7A -5246
MRM2 -5169
MT-CO3 -5157
MT-RNR1 -5094
MT-ND1 -5075
WDR36 -5072
BYSL -4898
RIOK1 -4858
UTP3 -4821
DHX37 -4742
MTREX -4495
RPP21 -4260
DIS3 -4140
RPL28 -3873
WDR18 -3817
FAU -3618
UBA52 -3490
UTP14A -3323
MPHOSPH6 -3194
RRP1 -3051
MT-CO2 -2523
UTP14C -2415
TRMT112 -2296
RPP14 -2204
MT-ATP6 -2202
MT-CYB -2032
PRORP -1720
RPL39L -1661
FTSJ3 -1199
DDX21 -1198
RPS26 -1154
MT-ND5 -931
WDR12 -731
RPS27L -496
EXOSC1 -493
MT-CO1 -454
MT-RNR2 -408
RRP36 -395
C1D -325
EXOSC3 -40
UTP11 -37
SENP3 78
MT-ATP8 189
RPS4Y1 331
FCF1 453
TBL3 739
TSR3 1498
NOC4L 1606
DDX52 1795
RPS9 1841
MT-ND4L 2323
NSUN4 2338
MT-TF 2765
HSD17B10 2981
ISG20L2 3150
MT-TV 3363
UTP18 3850
DDX49 4083
NOL12 4277
MT-ND4 4493
MT-TL1 4517
RPL3L 5150
RPL26L1 6001
ERI1 6679
RIOK3 7088
CSNK1D 8475
EXOSC4 10040
XRN2 10267
NOP10 10379
SNORD3A 10596


Major pathway of rRNA processing in the nucleolus and cytosol

Major pathway of rRNA processing in the nucleolus and cytosol
624
set Major pathway of rRNA processing in the nucleolus and cytosol
setSize 180
pANOVA 6.06e-50
s.dist -0.641
p.adjustANOVA 2.06e-47



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPP40 -10069
NOP58 -10031
RPL23A -9979
GNL3 -9960
RPL3 -9957
FBL -9942
NOL11 -9932
RPL5 -9881
RPS3A -9834
WDR75 -9823
RPL7 -9765
EXOSC2 -9753
TSR1 -9724
RPS27A -9723
UTP4 -9700
RPS6 -9699
RPL14 -9698
LAS1L -9679
RPS25 -9664
RPL22 -9659

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPP40 -10069
NOP58 -10031
RPL23A -9979
GNL3 -9960
RPL3 -9957
FBL -9942
NOL11 -9932
RPL5 -9881
RPS3A -9834
WDR75 -9823
RPL7 -9765
EXOSC2 -9753
TSR1 -9724
RPS27A -9723
UTP4 -9700
RPS6 -9699
RPL14 -9698
LAS1L -9679
RPS25 -9664
RPL22 -9659
NOP14 -9641
BMS1 -9626
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
NOP56 -9444
RPS20 -9413
RPL13A -9402
WDR43 -9395
RPS23 -9387
EXOSC8 -9379
RPL32 -9345
NCL -9336
DDX47 -9334
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
UTP15 -9156
RPL11 -9117
RPL17 -9116
WDR46 -9056
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
TEX10 -8915
RPL36A -8909
NOB1 -8908
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
MPHOSPH10 -8840
EXOSC9 -8793
NOL9 -8786
RPL31 -8769
EMG1 -8744
RPS13 -8724
RPL26 -8706
RPP25 -8688
RPS4X -8648
RPP30 -8640
RPS29 -8637
RPL39 -8635
RPL29 -8621
UTP6 -8616
RRP9 -8598
RPS16 -8579
RPS14 -8541
SNU13 -8495
RPS10 -8494
EXOSC7 -8473
EXOSC5 -8394
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
PELP1 -8232
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
RPS28 -8083
RIOK2 -8079
PNO1 -8004
RPS11 -7975
RPL38 -7968
EBNA1BP2 -7916
RPL37 -7861
NOL6 -7834
RPL27 -7810
RPS19 -7806
NIP7 -7779
KRR1 -7720
RCL1 -7690
RPP38 -7683
RPL13 -7671
DCAF13 -7564
RPL41 -7561
RPL36 -7493
EXOSC6 -7458
UTP20 -7427
HEATR1 -7278
IMP4 -7155
PES1 -7148
LTV1 -7119
WDR3 -7016
IMP3 -6912
RPL37A -6833
EXOSC10 -6829
RPL9 -6821
RPS24 -6818
RPS15 -6703
RPL36AL -6646
RPSA -6629
BOP1 -6593
PDCD11 -6547
CSNK1E -6526
RPL8 -6101
RPLP1 -6018
RBM28 -5712
PWP2 -5423
RRP7A -5246
WDR36 -5072
BYSL -4898
RIOK1 -4858
UTP3 -4821
DHX37 -4742
MTREX -4495
RPP21 -4260
DIS3 -4140
RPL28 -3873
WDR18 -3817
FAU -3618
UBA52 -3490
UTP14A -3323
MPHOSPH6 -3194
RRP1 -3051
UTP14C -2415
RPP14 -2204
RPL39L -1661
FTSJ3 -1199
DDX21 -1198
RPS26 -1154
WDR12 -731
RPS27L -496
EXOSC1 -493
RRP36 -395
C1D -325
EXOSC3 -40
UTP11 -37
SENP3 78
RPS4Y1 331
FCF1 453
TBL3 739
NOC4L 1606
DDX52 1795
RPS9 1841
ISG20L2 3150
UTP18 3850
DDX49 4083
NOL12 4277
RPL3L 5150
RPL26L1 6001
ERI1 6679
RIOK3 7088
CSNK1D 8475
EXOSC4 10040
XRN2 10267
SNORD3A 10596


Innate Immune System

Innate Immune System
534
set Innate Immune System
setSize 967
pANOVA 2.26e-44
s.dist 0.265
p.adjustANOVA 6.16e-42



Top enriched genes

Top 20 genes
GeneID Gene Rank
SLC11A1 11464
NCSTN 11452
C1QC 11448
C1QB 11445
DOK3 11443
P2RX1 11442
LILRB2 11437
HK3 11430
OSCAR 11425
IDH1 11418
SIRPA 11414
GNS 11410
SERPINA1 11407
CR1 11401
DNASE1L1 11385
SIGLEC9 11381
QSOX1 11369
PRKACA 11363
CD63 11355
MYO10 11353

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SLC11A1 11464
NCSTN 11452
C1QC 11448
C1QB 11445
DOK3 11443
P2RX1 11442
LILRB2 11437
HK3 11430
OSCAR 11425
IDH1 11418
SIRPA 11414
GNS 11410
SERPINA1 11407
CR1 11401
DNASE1L1 11385
SIGLEC9 11381
QSOX1 11369
PRKACA 11363
CD63 11355
MYO10 11353
MCEMP1 11349
RASGRP4 11346
MYD88 11331
WASF1 11328
FGR 11323
C1QA 11320
HP 11312
NCKAP1L 11304
IMPDH1 11303
CTSD 11297
C3AR1 11294
MAP3K8 11291
ATP6V0A1 11283
LAIR1 11276
ITGAM 11269
UNC13D 11266
CTSB 11250
MAPKAPK3 11249
NLRC4 11239
ITGAX 11231
ANPEP 11227
FPR1 11221
FCER1G 11216
TIMP2 11214
S100A12 11206
HCK 11202
MAPK1 11193
RNASE2 11192
TLR5 11191
CASP9 11186
S100A8 11184
ALOX5 11178
GUSB 11175
PRKCD 11168
TCIRG1 11138
TRPM2 11134
PGAM1 11128
PLAC8 11120
MAPK14 11115
RPS6KA1 11103
PLD1 11091
TRIM25 11088
NEU1 11082
SERPINB1 11081
NKIRAS2 11077
ACAA1 11076
CD177 11068
ALDH3B1 11063
C5AR1 11061
MMP25 11057
AGPAT2 11054
PLEKHO2 11053
MEFV 11043
ADGRG3 11019
ATP6V0D1 11016
RIPK3 11013
VNN1 11000
GCA 10999
ATP6V0C 10995
RNF135 10992
ARPC1A 10981
VAT1 10971
BRI3 10962
MAP2K6 10958
RAB10 10956
PYGL 10952
MGAM 10950
CD36 10947
CD93 10937
MOSPD2 10933
CEACAM3 10932
MMP9 10920
CD55 10914
S100A11 10910
IRAK3 10909
NFAM1 10890
FPR2 10883
GYG1 10873
ALDOA 10868
ITGB2 10861
CDA 10859
BTK 10849
TLR8 10847
GM2A 10846
CTSA 10842
GRN 10837
ALPK1 10833
MYO9B 10832
CKAP4 10819
NLRX1 10815
CRISPLD2 10814
NCF4 10813
CLU 10812
LYN 10810
WASF2 10807
ASAH1 10796
NCF2 10793
ATP11A 10791
LRG1 10785
ARPC1B 10781
WAS 10777
CYB5R3 10775
TSPAN14 10759
NBEAL2 10743
GRB2 10733
RETN 10732
SLC2A3 10714
ANXA2 10704
QPCT 10700
C2 10689
SLC15A4 10684
RAB3D 10677
C5AR2 10670
RAB31 10661
LAT2 10657
BST1 10647
RHOG 10635
GPR84 10632
RAC1 10624
CD300E 10618
SIGLEC16 10616
S100A9 10613
ACTB 10606
CYSTM1 10605
GLA 10595
TOM1 10594
CAPN1 10570
GSN 10558
TNFAIP6 10555
CD68 10546
LTA4H 10541
PYCARD 10540
TLR2 10535
GAB2 10528
UNC93B1 10526
PKM 10523
IGF2R 10494
PLAUR 10490
FCGR2A 10470
PSTPIP1 10451
ALAD 10449
PTPN6 10446
LILRB3 10433
PSEN1 10429
CYFIP1 10420
PECAM1 10414
CLEC4D 10398
CRK 10387
PGM2 10380
MAP2K3 10377
DNM2 10373
DNAJC5 10371
CD300A 10362
PTPRJ 10340
COTL1 10333
CD53 10308
CTSL 10288
ACLY 10268
SYK 10256
PADI2 10252
PLCG2 10244
VAV1 10226
AP2A2 10223
FCAR 10219
GLB1 10217
TMBIM1 10197
SIGLEC15 10194
ELMO2 10190
PTAFR 10188
AMPD3 10183
CYBA 10173
DOCK2 10155
MAP2K1 10148
NAPRT 10133
RAB7A 10115
CAT 10103
ARPC5 10102
FTL 10101
PSMD4 10088
TNFRSF1B 10079
ARG1 10061
TLR1 10059
ARL8A 10056
PAK1 10043
ARSB 10041
IQGAP1 10037
MAPK7 10035
ADAM10 9992
CPPED1 9991
NOD2 9983
ATP6V1D 9982
SELL 9974
RAB6A 9958
SDCBP 9947
CTSZ 9943
CAP1 9934
DNAJC13 9921
S100P 9918
IGLV7-43 9914
ATP6V1C1 9900
MEF2A 9891
RAB5C 9864
STAT6 9852
MGST1 9847
CDC34 9836
DNAJC3 9831
DBNL 9815
CFL1 9794
EP300 9789
TEC 9787
ATP6V0B 9782
MAPK3 9750
BIN2 9720
LAMP1 9712
ARHGAP9 9702
CD58 9688
RAF1 9686
TOLLIP 9682
ACTG1 9678
HSPA6 9675
CTNNB1 9670
CYBB 9660
MAPK13 9645
TYROBP 9637
VAPA 9635
RAB24 9634
RAB27A 9628
CCR2 9605
AP1M1 9595
ARPC4 9592
IGKV1-39 9590
TLR4 9549
MYO5A 9548
SHC1 9541
ATP6V1A 9534
CAPZA1 9530
CSTB 9479
CD14 9466
GMFG 9443
IKBKG 9441
ATP6V1B2 9436
RHOA 9401
CAB39 9379
FCGR3A 9377
ABI1 9373
DERA 9344
HSPA1A 9341
CXCR1 9335
LY96 9322
VPS35L 9320
UBE2D1 9286
CTSC 9276
TXN 9268
LAMTOR1 9265
CANT1 9259
CD44 9255
SIGLEC5 9235
MYH9 9224
LGALS3 9180
SNAP29 9157
CNN2 9140
PIK3CB 9126
DTX4 9123
PELI3 9118
TRAPPC1 9087
TLR6 9070
CEACAM1 9052
GALNS 9046
PAK2 9042
LAMP2 9034
ARPC2 9016
PDAP1 9011
IST1 8994
STK10 8992
CMTM6 8960
NLRP3 8955
ADAM8 8938
ADGRE5 8937
ACTR2 8895
PSAP 8894
MNDA 8892
PLD2 8890
TICAM1 8878
CFP 8875
ACTR3 8873
STK11IP 8872
NCKAP1 8861
TIRAP 8858
MAPKAPK2 8852
MAPK10 8849
HPSE 8832
APAF1 8822
HSPA1B 8806
LRRFIP1 8804
FADD 8785
PSMD9 8766
ARPC3 8726
CHUK 8723
PSME3 8716
PDPK1 8710
MMP8 8706
WIPF2 8699
ROCK1 8695
CREG1 8692
UBE2D3 8641
GAA 8625
MVP 8603
TANK 8576
HEBP2 8559
ATP11B 8523
FCGR1A 8520
PRCP 8518
DUSP3 8510
CLEC5A 8487
SLCO4C1 8486
DDOST 8464
PSMB7 8460
ARSA 8456
RAB4B 8449
TUBB4B 8440
IQGAP2 8437
ATP6V0E1 8417
VAV3 8413
KCMF1 8403
CLEC4E 8358
CDC42 8342
OSTF1 8338
SURF4 8306
DYNC1LI1 8276
PDXK 8267
PSMB5 8265
IKBKE 8263
RAB5B 8258
PANX1 8253
RAC2 8237
CAPZA2 8225
ATP6V1E1 8198
PRKCE 8190
PSMD1 8184
CREBBP 8143
PSMD2 8139
MAVS 8131
LIMK1 8062
PNP 8043
PTPRC 8021
LAMTOR2 8006
PSMB3 8005
COPB1 7997
STOM 7990
IRAK1 7970
RNASET2 7961
FCN1 7954
PGLYRP2 7911
CLEC6A 7906
FABP5 7903
ITGAV 7847
PSMA7 7840
TREM1 7815
TNIP2 7810
VCP 7804
C4B 7784
CARD9 7777
PSMD11 7775
B4GALT1 7763
MAP2K4 7754
UBA3 7741
ITPR2 7716
LPCAT1 7696
HEXB 7695
MANBA 7689
PSMD5 7646
OLFM4 7638
RAP2C 7598
DOCK1 7594
FAF2 7588
CNPY3 7565
SNAP23 7530
CFB 7474
PPP2CB 7451
UBE2M 7401
PSMB6 7399
BCL10 7391
RAP1A 7335
CLEC4A 7313
PSMD6 7307
YPEL5 7288
NCF1 7245
CRCP 7239
PGM1 7238
GGH 7233
VRK3 7206
COMMD9 7156
SIRPB1 7136
DIAPH1 7128
GPI 7117
AHCYL1 7116
ATP6V1H 7104
CXCL1 7072
RAB18 7038
TMEM30A 7030
RAP1B 6962
GDI2 6949
CD33 6932
DYNLT1 6926
FTH1 6883
NFKBIB 6845
CASP4 6841
C6orf120 6840
PRKCSH 6831
PSMD12 6820
PPP2CA 6806
ITCH 6755
IGLV10-54 6741
CXCR2 6720
METTL7A 6718
HBB 6697
CGAS 6692
TAB3 6655
RNASE6 6610
PPP2R5D 6601
UBR4 6594
CD46 6547
PTPN11 6524
ATOX1 6512
PIK3R2 6511
CTSS 6504
FUCA1 6469
C4BPA 6442
MUC5B 6394
KCNAB2 6369
PLD3 6346
PIGR 6337
MUC16 6329
MAP3K1 6286
RAB3A 6284
APP 6245
ICAM3 6195
VCL 6193
LRMP 6184
PELI2 6164
UBC 6135
KRAS 6132
ABL1 6127
PPP3CB 6126
ATG7 6082
FUCA2 6028
DNM1 5998
PAFAH1B2 5996
ATP7A 5970
NDUFC2 5943
ACTR10 5886
CSNK2B 5876
MAN2B1 5768
PSMD8 5687
STBD1 5663
SIGLEC14 5662
SERPINB10 5629
FBXW11 5621
KPNB1 5604
PPP3R1 5564
RAB14 5469
NFKBIA 5457
ELMO1 5455
LAMTOR3 5383
CTSK 5320
SERPINB6 5280
TAX1BP1 5257
ATP8B4 5252
PSMA6 5209
PPP2R1A 5189
SLC44A2 5180
DGAT1 5173
UBE2K 5166
POLR2E 5109
PRDX6 5085
SRP14 5022
NHLRC3 5010
CTSH 4985
TKFC 4982
BCL2L1 4964
PSMC6 4959
APEH 4945
PDZD11 4944
ATP6AP2 4915
PGLYRP1 4910
NRAS 4907
AGER 4895
CD300LB 4879
TBK1 4856
PTPRN2 4854
PSMC1 4827
ERP44 4818
PELI1 4802
C1R 4765
TRIM21 4745
IGKV5-2 4704
SOCS1 4688
GLIPR1 4675
TRAF6 4673
C5 4661
OTUD5 4604
CLEC7A 4602
ARMC8 4598
PSMC2 4543
MUC1 4458
IGLV2-11 4439
RPS6KA2 4384
NFASC 4356
MAGT1 4339
PSMD3 4297
TICAM2 4262
PSMF1 4259
POLR2F 4256
CD59 4252
PROS1 4191
ITLN1 4168
NF2 4139
IRF7 4132
MAP3K7 4043
NOS1 4024
TARM1 3952
IGLC3 3928
RAP2B 3915
PLAU 3907
ATP6V1F 3811
PSMD13 3766
LCP2 3759
P2RX7 3740
IGKV1D-39 3734
ITGAL 3647
PPP3CA 3538
DNM3 3523
SEM1 3454
ANO6 3404
NPC2 3326
C1S 3306
WASL 3297
HTN1 3261
POLR3A 3224
RIPK1 3206
WIPF1 3137
DEGS1 3135
JUN 3122
PSMA1 3111
C4A 3032
CPNE3 2985
HLA-C 2969
CASP1 2896
NFKB1 2860
FOS 2787
VAV2 2755
FOLR3 2736
BIRC2 2697
FRK 2672
ATF1 2556
LPO 2539
MUC6 2538
AOC1 2506
DDX41 2414
RELB 2367
CLEC12A 2330
ECSIT 2321
LCN2 2300
CLEC4C 2219
EPPIN 2149
PIK3CA 2133
CDK13 2118
PSMD7 2084
ORM1 2075
HLA-E 2060
IGKV1-17 2037
CASP2 2017
POLR2L 2016
TAB2 1975
GHDC 1853
XRCC5 1832
PSME4 1818
PSMB2 1760
IKBKB 1759
VTN 1756
TAB1 1754
CST3 1747
DYNC1H1 1705
POLR1D 1703
DDX3X 1692
IFI16 1590
PTX3 1567
MAP2K7 1550
DYNLL1 1530
CRISP3 1416
FCGR3B 1391
ADGRE3 1240
HUWE1 1218
CRACR2A 1215
RBSN 1171
LY86 1163
UBB 1026
CASP10 1005
PSMD14 941
PSMC3 916
SYNGR1 852
MLEC 796
MME 695
RPS6KA3 649
PSMB4 642
IGHV1-46 618
PSMC4 605
PIN1 577
ORM2 565
CFD 461
PTK2 388
GSDMD 370
AGL 316
PCBP2 240
TREX1 144
STING1 94
PPP2R1B 89
GOLGA7 14
TLR9 -36
PGRMC1 -59
HLA-B -98
IGHV1-69 -113
VAMP8 -139
LEAP2 -163
EEA1 -171
RELA -204
HVCN1 -250
ENPP4 -308
LRRC7 -340
RNASE3 -371
IGLV1-44 -417
PYGB -418
PSMB8 -438
FRMPD3 -550
DSP -573
AIM2 -585
ATF2 -657
S100A1 -688
HGSNAT -737
GSTP1 -759
CYFIP2 -775
BST2 -782
NME2 -791
UBE2D2 -801
PRDX4 -834
IGKV2D-28 -844
MYO1C -962
IGHG1 -1043
RAB37 -1057
LYZ -1067
IGHG2 -1078
IGHV3-30 -1129
KLRC2 -1182
CALM1 -1245
UBE2V1 -1252
MAPK12 -1261
S100B -1351
WASF3 -1364
IGLV1-40 -1411
CPN2 -1422
NLRC5 -1423
A1BG -1468
IGKV2-28 -1472
IGKV3D-20 -1473
TIFA -1479
CPNE1 -1632
TMEM179B -1671
TUBB -1675
IGLV1-47 -1695
TCN1 -1708
PIK3C3 -1718
IGKV2-30 -1785
HSP90B1 -1788
IGLV3-27 -1836
MUC12 -1866
BAIAP2 -1877
CHIT1 -1890
PPBP -1960
KLRD1 -1984
POLR3K -2014
IGKV3-20 -2065
UBE2N -2071
GRAP2 -2088
PIK3R4 -2097
DUSP4 -2116
TXNDC5 -2141
IGKV1-12 -2196
IGHG4 -2238
TNFAIP3 -2285
RIPK2 -2451
DUSP7 -2452
IGHV3-11 -2459
PSMD10 -2515
BRK1 -2561
IGLV1-36 -2563
COMMD3 -2657
POLR3GL -2666
JUP -2668
HLA-H -2741
CCT8 -2751
PSMA4 -2764
POLR3B -2765
IGHV2-70 -2783
IRAK2 -2799
PSMA2 -2823
TRIM56 -2843
YES1 -2846
IGLV2-23 -2848
ATP6V1C2 -2926
IGLC7 -2940
SOS1 -2983
IGHV3-23 -2995
UBA7 -3029
IGLV3-25 -3048
SVIP -3052
DUSP6 -3055
IGHV2-5 -3063
IGHV4-39 -3179
SUGT1 -3240
IL1B -3269
ATG5 -3311
SLPI -3392
C3 -3394
RAB44 -3423
KIR2DS4 -3474
PLPP5 -3477
UBA52 -3490
PFKL -3512
NFKB2 -3527
MASP2 -3571
MUCL1 -3608
PSMB1 -3610
C8G -3626
CD81 -3627
NOD1 -3652
ITPR1 -3676
NCKIPSD -3692
IGLV4-69 -3702
CTSV -3775
DHX9 -3778
IGKV1-5 -3791
IGHV4-59 -3832
CLEC10A -3847
IGLC1 -3870
DHX58 -3871
ATP6V1E2 -3894
IGKC -3956
CREB1 -3977
HSP90AA1 -4016
PSMB10 -4050
PRKDC -4064
IGHV3-13 -4159
RAB9B -4177
DHX36 -4199
BTRC -4212
IGHG3 -4311
PTPRB -4321
ILF2 -4378
GNLY -4390
C4BPB -4446
POLR3C -4461
LTF -4464
IGLV8-61 -4469
IGHV3-7 -4523
PSMC5 -4553
CD19 -4586
CD209 -4595
MAPK11 -4641
IGLC2 -4647
ATP6V1G1 -4775
EPX -4781
CASP8 -4824
NLRP1 -4847
POLR2K -4907
SIKE1 -5045
IGHV3-53 -5054
TXNIP -5058
ISG15 -5074
HRNR -5086
IGKV1-33 -5088
IGLV2-8 -5148
FYN -5211
PA2G4 -5255
KRT1 -5265
HRAS -5273
DSN1 -5307
IGHV1-2 -5353
BPI -5410
MAPK9 -5454
PTGES2 -5466
MUC4 -5589
ALDOC -5613
IGLV7-46 -5638
IGLV1-51 -5706
CHI3L1 -5761
PI3 -5828
ELK1 -5884
PAK3 -5908
ATG12 -5923
ACTR1B -5952
ZBP1 -5983
HLA-A -5985
CD180 -6005
DPP7 -6012
FGL2 -6015
MEF2C -6025
IGLV3-12 -6030
RASGRP2 -6127
ITPR3 -6139
NFATC1 -6177
ORMDL3 -6182
POLR2H -6200
NKIRAS1 -6234
IGHV3-48 -6262
TLR7 -6272
SLC27A2 -6278
EEF2 -6279
IGKV3-15 -6284
SKP1 -6297
AAMP -6320
IGLV6-57 -6338
PPIE -6341
IGLV3-1 -6354
SRC -6396
IGHV4-34 -6414
PSMA3 -6433
DEFA3 -6439
SLC2A5 -6479
PPIA -6498
CR2 -6534
TMC6 -6551
KLRK1 -6555
ATP6V0A2 -6587
IGLV5-45 -6611
NFATC3 -6650
IGHE -6665
MRE11 -6668
HMGB1 -6699
CFH -6709
IRF3 -6721
HERC5 -6774
SIGIRR -6838
CD4 -6881
IGKV1-16 -6894
ABCA13 -6934
B2M -6943
BCL2 -6977
MUC20 -6993
MS4A3 -7001
RNF216 -7008
CAND1 -7058
TLR10 -7067
MIF -7102
POLR3G -7146
GZMM -7149
PLA2G6 -7168
NOS3 -7169
IGLV2-14 -7284
SCAMP1 -7313
IGKV4-1 -7319
PSME2 -7327
IGLV3-19 -7364
TLR3 -7411
TRAF2 -7465
PSMA5 -7476
IFIH1 -7494
DDX58 -7512
TRAF3 -7539
CEACAM8 -7546
APRT -7580
TBC1D10C -7608
SERPING1 -7610
OLR1 -7621
AGA -7674
DEFA1 -7680
LGMN -7705
DEFA4 -7723
UBE2L6 -7739
POLR3F -7749
PSME1 -7778
TMEM63A -7978
IGLV2-18 -8002
CD3G -8111
XRCC6 -8146
CEP290 -8156
ABI2 -8174
TRIM32 -8252
MPO -8263
CEACAM6 -8277
SARM1 -8283
IGHV3-33 -8309
MS4A2 -8347
ATAD3B -8354
IGLV3-21 -8363
ELANE -8371
PTPN4 -8389
CAMP -8417
PSMB9 -8503
NFATC2 -8513
NLRC3 -8550
POLR3E -8594
MAP3K14 -8618
RHOF -8679
CARD11 -8722
CD247 -8741
HMOX2 -8794
PIK3R1 -8831
MAPK8 -8929
NCK1 -8975
POLR3D -9004
HSPA8 -9129
POLR1C -9141
ATP6V1G2 -9143
NIT2 -9152
CD47 -9164
HSP90AB1 -9172
ATP8A1 -9218
PRTN3 -9350
AZU1 -9380
RPS6KA5 -9386
RASGRP1 -9394
PLCG1 -9412
CUL1 -9420
PRKCQ -9424
IGKV3-11 -9449
ATP6V0E2 -9456
SPTAN1 -9461
FCER1A -9468
LAT -9470
CTSG -9503
LCK -9556
ICAM2 -9588
TXK -9627
DSC1 -9630
ITK -9674
POLR3H -9693
RPS27A -9723
EEF1A1 -9751
RNF125 -9797
PRKACB -9863
CYLD -9961
CCT2 -10024
BIRC3 -10039
MALT1 -10050
CCR6 -10108
PLD4 -10109
IMPDH2 -10126


Translation

Translation
1266
set Translation
setSize 295
pANOVA 9.42e-40
s.dist -0.446
p.adjustANOVA 2.14e-37



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
MRPS6 -9838
RPS3A -9834
RPL7 -9765
EEF1A1 -9751
NARS2 -9738
EEF1B2 -9732
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
LARS1 -9637
EIF4A2 -9593
RPS2 -9591
FARS2 -9569
RPL4 -9549
EIF3B -9526

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
MRPS6 -9838
RPS3A -9834
RPL7 -9765
EEF1A1 -9751
NARS2 -9738
EEF1B2 -9732
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
LARS1 -9637
EIF4A2 -9593
RPS2 -9591
FARS2 -9569
RPL4 -9549
EIF3B -9526
RPL21 -9511
RPL34 -9492
GFM1 -9467
MRPS33 -9440
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
MRPL50 -9302
RPS3 -9298
EEF1G -9293
RPL35A -9291
N6AMT1 -9282
MRPS25 -9279
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
MRPS27 -9147
RPL11 -9117
RPL17 -9116
EIF3E -9049
RPL27A -9048
RPS5 -9042
RPL10 -9031
IARS1 -8999
RPL30 -8930
RPL10A -8928
MRPS9 -8917
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
MRPL48 -8859
RPL31 -8769
RPS13 -8724
RPL26 -8706
MRPL24 -8692
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
FARSB -8580
RPS16 -8579
EARS2 -8562
RPS14 -8541
RPS10 -8494
MRPL46 -8479
EIF1AX -8383
KARS1 -8380
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
MRPS30 -8262
EIF3L -8255
AARS2 -8248
RPL22L1 -8202
EIF4B -8190
RPL35 -8183
RPL15 -8169
MRPS18B -8125
RPS28 -8083
MRPL17 -8047
GSPT2 -7995
MRPL32 -7992
AIMP1 -7990
RPS11 -7975
RPL38 -7968
MARS2 -7955
MRPL39 -7936
SARS2 -7925
RPL37 -7861
RPL27 -7810
RPS19 -7806
RPL13 -7671
WARS2 -7615
MRPL1 -7594
RPL41 -7561
SRPRB -7520
MRPL38 -7496
RPL36 -7493
MRPS2 -7237
MRPL42 -7224
MRPL9 -7188
EIF3H -7091
DAP3 -7087
MRPL45 -6990
DARS1 -6939
MRPS17 -6909
EIF5B -6867
RPL37A -6833
HARS1 -6831
RPL9 -6821
RPS24 -6818
EIF3M -6817
AARS1 -6785
MRPL14 -6728
MRPS14 -6718
RPS15 -6703
MRPS7 -6677
EIF2B3 -6649
RPL36AL -6646
RPSA -6629
PTCD3 -6500
TRAM1 -6480
EIF3J -6448
EPRS1 -6350
MRPS21 -6319
EEF2 -6279
LARS2 -6268
MRPS28 -6255
RPL8 -6101
TSFM -6082
SEC11C -6046
SARS1 -6044
RPLP1 -6018
PPA1 -5970
MRPL35 -5957
MRPL3 -5916
EEF1A1P5 -5877
EEF1D -5664
MRPS12 -5654
MRPL49 -5619
MRPL54 -5616
EIF2B5 -5580
MRRF -5487
MRPL11 -5474
MRPS26 -5430
SEC61A2 -5333
EIF3F -5200
EIF3D -5158
MT-RNR1 -5094
MRPL57 -5039
YARS2 -5018
MRPL34 -4765
EIF3C -4716
MRPL43 -4449
MRPL27 -4262
MRPS23 -4230
MRPL19 -4123
VARS1 -4083
MRPL58 -3985
RARS1 -3944
RPL28 -3873
MRPS31 -3868
MRPL12 -3819
RARS2 -3810
QARS1 -3758
WARS1 -3717
VARS2 -3646
FAU -3618
SRP72 -3562
MRPL55 -3524
UBA52 -3490
MRPL41 -3438
SRP9 -3414
AIMP2 -3343
MRPS35 -3315
MRPL18 -3314
EEF1A2 -3246
SEC61G -3152
MTIF2 -3020
PABPC1 -2991
MRPL40 -2981
MRPL15 -2975
SSR2 -2917
GADD45GIP1 -2813
EIF3G -2746
MRPS10 -2725
EEF1E1 -2716
EIF3I -2580
MRPL21 -2473
PPA2 -2453
MRPL2 -2449
MRPL30 -2421
MRPS22 -2388
EIF3K -2369
TRMT112 -2296
EIF2B1 -2228
MRPS34 -2208
MRPS18C -2145
MRPL47 -2119
GSPT1 -2025
MRPL4 -1924
MRPL16 -1832
SPCS1 -1700
RPL39L -1661
EIF2S1 -1649
MRPL20 -1647
IARS2 -1595
ERAL1 -1389
EIF3A -1276
NARS1 -1189
RPS26 -1154
SPCS2 -977
MRPS15 -924
SRP19 -625
FARSA -514
RPS27L -496
MRPS36 -492
MRPL22 -462
MT-RNR2 -408
MRPL13 -237
MRPL37 177
MTIF3 221
RPS4Y1 331
MRPS16 350
EIF2S2 554
SRP68 787
TARS2 801
PARS2 910
MRPS24 1048
SSR1 1143
SSR4 1294
MRPS18A 1407
GFM2 1540
MRPL36 1646
EIF4E 1661
YARS1 1707
TARS1 1786
OXA1L 1825
RPS9 1841
MRPL44 1847
SPCS3 1967
MRPS11 2087
MRPS5 2484
EIF2S3 2500
SSR3 2510
MRPL51 2595
MRPL33 2637
HARS2 2776
EIF4EBP1 2825
EIF5 2937
DARS2 2971
MT-TV 3363
TUFM 3457
CHCHD1 3643
MRPL52 4004
MRPL10 4156
EIF2B4 4294
SEC61B 4322
MTFMT 4587
MRPL23 4865
APEH 4945
SRP14 5022
RPL3L 5150
MTRF1L 5386
EIF4A1 5541
AURKAIP1 5758
RPL26L1 6001
MRPL53 6626
SEC11A 6634
GARS1 6727
ETF1 6835
RPN1 7151
MARS1 7358
SEC61A1 7486
EIF2B2 7498
EIF4H 7768
SRP54 7912
SRPRA 8301
DDOST 8464
CARS2 8664
RPN2 8874
MRPL28 9785
EIF4G1 10506
CARS1 10656


Metabolism of RNA

Metabolism of RNA
634
set Metabolism of RNA
setSize 685
pANOVA 1.65e-39
s.dist -0.294
p.adjustANOVA 3.21e-37



Top enriched genes

Top 20 genes
GeneID Gene Rank
DKC1 -10139
NDC1 -10077
MT-TP -10070
RPP40 -10069
NOP58 -10031
RPL23A -9979
ALKBH8 -9977
GNL3 -9960
RPL3 -9957
FBL -9942
NOL11 -9932
MTERF4 -9917
RPL5 -9881
RPS3A -9834
RBMX -9832
NAT10 -9828
WDR75 -9823
METTL1 -9815
THUMPD1 -9782
THOC3 -9772

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DKC1 -10139
NDC1 -10077
MT-TP -10070
RPP40 -10069
NOP58 -10031
RPL23A -9979
ALKBH8 -9977
GNL3 -9960
RPL3 -9957
FBL -9942
NOL11 -9932
MTERF4 -9917
RPL5 -9881
RPS3A -9834
RBMX -9832
NAT10 -9828
WDR75 -9823
METTL1 -9815
THUMPD1 -9782
THOC3 -9772
RPL7 -9765
EXOSC2 -9753
NUP35 -9726
TSR1 -9724
RPS27A -9723
GCFC2 -9707
UTP4 -9700
RPS6 -9699
RPL14 -9698
LAS1L -9679
NUP88 -9668
RPS25 -9664
RPL22 -9659
GEMIN4 -9658
DIMT1 -9652
NOP14 -9641
NCBP2 -9631
BMS1 -9626
EIF4A2 -9593
RPS2 -9591
SEH1L -9574
RPL4 -9549
RPL21 -9511
TRMT11 -9508
RPL34 -9492
NOP56 -9444
RPS20 -9413
RPL13A -9402
WDR43 -9395
RPS23 -9387
ZNF473 -9381
EXOSC8 -9379
TYW1 -9363
MYC -9357
RPL32 -9345
QTRT1 -9338
NCL -9336
DDX47 -9334
RPL6 -9309
RPS3 -9298
RPL35A -9291
SRSF5 -9275
RPS12 -9270
TRMT61B -9259
PUS7 -9235
RPLP0 -9227
TYW3 -9215
LSM5 -9206
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
UTP15 -9156
DDX20 -9146
HSPA8 -9129
RPL11 -9117
RPL17 -9116
LSM11 -9085
WDR46 -9056
RPL27A -9048
RPS5 -9042
WDR77 -9040
RPL10 -9031
PPIH -9028
SRSF11 -9002
RPL30 -8930
RPL10A -8928
TEX10 -8915
RPL36A -8909
NOB1 -8908
RPL24 -8901
RPL18A -8896
CNOT7 -8894
RPS15A -8883
DCP1B -8881
RPL18 -8863
RPS8 -8861
MPHOSPH10 -8840
SRSF10 -8821
UPF3A -8795
EXOSC9 -8793
NOL9 -8786
TSEN2 -8784
RPL31 -8769
EMG1 -8744
SNRNP40 -8734
RPS13 -8724
RPL26 -8706
NXT1 -8699
HNRNPA3 -8697
RPP25 -8688
SNRPF -8687
TRMT13 -8669
RPS4X -8648
RPP30 -8640
RPS29 -8637
RPL39 -8635
RPL29 -8621
UTP6 -8616
RRP9 -8598
RPS16 -8579
SRSF6 -8576
SNRPE -8564
SF3A3 -8563
SNRPN -8556
RPS14 -8541
GTF2H3 -8537
MRM1 -8526
SF3B3 -8519
TSEN15 -8515
PSMB9 -8503
SNU13 -8495
RPS10 -8494
RAN -8475
HNRNPA0 -8474
EXOSC7 -8473
HNRNPR -8443
TNKS1BP1 -8421
EXOSC5 -8394
RPL23 -8373
NUP43 -8368
NUP160 -8357
RPL19 -8338
RPS21 -8330
CNOT6L -8322
RPS18 -8321
NOP2 -8307
TRMT10C -8306
RPL7A -8286
NUP107 -8285
RPS17 -8281
PELP1 -8232
RBM17 -8218
GTF2H1 -8203
RPL22L1 -8202
EIF4B -8190
RPL35 -8183
RPL15 -8169
PHAX -8164
HNRNPA1 -8155
WBP11 -8149
PRPF19 -8121
RPS28 -8083
RIOK2 -8079
RNPS1 -8030
PNO1 -8004
OSGEP -7996
GSPT2 -7995
LSM7 -7987
RPS11 -7975
RPL38 -7968
NUP188 -7953
THOC1 -7949
EBNA1BP2 -7916
TP53RK -7907
RPL37 -7861
LSM4 -7839
POP5 -7837
TPRKB -7836
NOL6 -7834
RPL27 -7810
RPS19 -7806
NUDT21 -7791
SET -7783
NIP7 -7779
PSME1 -7778
KRR1 -7720
SNRNP70 -7713
TSEN54 -7696
RCL1 -7690
RPP38 -7683
RPL13 -7671
PUS1 -7669
CLNS1A -7640
ADAT2 -7613
RNMT -7569
DCAF13 -7564
RPL41 -7561
GTPBP3 -7547
SNRPD2 -7545
NUP205 -7516
RPL36 -7493
LSM8 -7483
PSMA5 -7476
EXOSC6 -7458
UTP20 -7427
GAR1 -7407
THG1L -7403
PPWD1 -7374
GEMIN8 -7368
PPIL1 -7334
PSME2 -7327
HNRNPH1 -7320
HEATR1 -7278
SF3B1 -7276
CSTF1 -7266
SNRPA1 -7256
SRSF7 -7229
TTC37 -7177
PLRG1 -7159
IMP4 -7155
PES1 -7148
NUP54 -7131
LTV1 -7119
TRMT61A -7077
NUP155 -7061
MTO1 -7022
WDR3 -7016
IMP3 -6912
TFB1M -6859
POLR2D -6856
RPL37A -6833
EXOSC10 -6829
RPL9 -6821
RPS24 -6818
DDX1 -6788
MAGOHB -6726
THADA -6715
SNRPD1 -6705
RPS15 -6703
FYTTD1 -6647
RPL36AL -6646
RPSA -6629
DDX5 -6600
BOP1 -6593
PDCD11 -6547
NHP2 -6535
CSNK1E -6526
NUP93 -6458
PSMA3 -6433
TRMT1 -6407
LCMT2 -6376
SNRPD3 -6352
EPRS1 -6350
PPIE -6341
MNAT1 -6327
PRPF6 -6242
POLR2H -6200
SRSF2 -6188
METTL3 -6122
RPL8 -6101
MT-ND2 -6095
RPLP1 -6018
BCAS2 -5975
CDKAL1 -5902
UPF3B -5843
PDCD7 -5777
SF3A2 -5775
RBM28 -5712
MRM3 -5709
SRRT -5701
XPOT -5659
POP1 -5627
FAM98B -5622
SRSF3 -5550
TRNT1 -5539
MT-ND3 -5522
APOBEC2 -5509
PPIL3 -5431
PWP2 -5423
ELAC2 -5385
LAGE3 -5360
TRIT1 -5352
NUP133 -5346
TRMU -5295
RRP7A -5246
FTSJ1 -5188
TRMT44 -5173
MRM2 -5169
TRMT5 -5160
MT-CO3 -5157
NT5C3B -5144
WDR4 -5100
MT-RNR1 -5094
MT-ND1 -5075
WDR36 -5072
C2orf49 -4997
SNRNP200 -4953
POLR2K -4907
BYSL -4898
DHX15 -4896
RIOK1 -4858
DCP1A -4839
PRPF31 -4832
CTU2 -4830
UTP3 -4821
RTRAF -4768
PAIP1 -4755
DHX37 -4742
PQBP1 -4696
MAGOH -4678
MAPK11 -4641
PSMC5 -4553
GEMIN6 -4524
U2SURP -4521
SNRNP48 -4519
MTREX -4495
APOBEC3H -4368
TGS1 -4316
GEMIN5 -4269
RPP21 -4260
SNRPB -4187
DIS3 -4140
PSMB10 -4050
NUP42 -4045
CPSF4 -4025
RNPC3 -4007
NUP210 -3949
PARN -3946
POLR2I -3929
SMN1 -3889
RPL28 -3873
FUS -3863
PRPF8 -3849
TRA2B -3839
PRPF3 -3837
HNRNPD -3823
WDR18 -3817
DHX9 -3778
H19 -3763
DDX39A -3754
TPR -3744
PNRC2 -3729
SUPT5H -3672
FAU -3618
PSMB1 -3610
CCAR1 -3543
UBA52 -3490
LSM3 -3478
CWC22 -3466
NUP85 -3427
POLR2B -3384
GEMIN2 -3379
SNRPB2 -3333
AAAS -3332
UTP14A -3323
XPO1 -3214
MPHOSPH6 -3194
ELAVL1 -3119
RRP1 -3051
SNRPC -3044
PABPC1 -2991
EDC4 -2950
PTBP1 -2842
MT-ND6 -2833
PSMA2 -2823
SLBP -2817
PSMA4 -2764
CNOT10 -2678
ADARB1 -2646
THOC2 -2624
PPIL4 -2614
CNOT2 -2544
THOC6 -2527
MT-CO2 -2523
PSMD10 -2515
ZCRB1 -2492
UTP14C -2415
NUP62 -2410
PRKCA -2408
WDR61 -2390
DNAJC8 -2315
METTL14 -2300
TRMT112 -2296
NUP37 -2275
ZRSR2 -2212
RPP14 -2204
MT-ATP6 -2202
ALYREF -2176
SRRM1 -2172
XRN1 -2167
U2AF1L4 -2154
CWC15 -2120
MT-CYB -2032
GSPT1 -2025
ZC3H11A -2004
SNRNP25 -1995
TRMT12 -1884
CHERP -1876
FIP1L1 -1860
PABPN1 -1789
PUF60 -1760
URM1 -1729
PRORP -1720
POM121C -1710
GTF2H5 -1698
RPL39L -1661
PHF5A -1599
SRSF1 -1573
HSPB1 -1544
RBM8A -1499
POP7 -1436
ADAT1 -1317
APOBEC3C -1287
FTSJ3 -1199
DDX21 -1198
RPS26 -1154
RANBP2 -1141
SF3B5 -997
DDX39B -960
NCBP1 -942
MT-ND5 -931
A1CF -907
CSTF2T -904
PAN2 -899
CSTF2 -856
TRDMT1 -835
GTF2H4 -803
MT-TS1 -757
WDR12 -731
SARNP -641
CPSF1 -561
HBS1L -509
RPS27L -496
POLR2C -494
EXOSC1 -493
SMG1 -489
SMG6 -480
WDR33 -474
RTCB -467
MT-CO1 -454
PSMB8 -438
MT-RNR2 -408
RRP36 -395
C1D -325
PRPF38A -184
POM121 -142
DDX6 -136
SNRPA -44
EXOSC3 -40
UTP11 -37
LSM2 -5
GEMIN7 9
POP4 56
SENP3 78
NSUN6 84
SF3A1 86
CWC27 110
MT-ATP8 189
PCBP2 240
NUP153 254
DDX46 256
RPS4Y1 331
PRPF40A 336
THOC7 348
SLU7 354
XAB2 437
FCF1 453
U2AF2 483
SNRPG 560
PSMC4 605
PSMB4 642
RBM5 643
SF1 726
TBL3 739
ISY1 828
PSMC3 916
PSMD14 941
UBB 1026
SRRM2 1039
SYF2 1107
SYMPK 1165
PUS3 1168
KHSRP 1173
CHTOP 1241
NSUN2 1256
UPF2 1281
HNRNPF 1319
LSM1 1325
CNOT11 1459
TYW5 1485
TSR3 1498
HNRNPU 1501
EIF4A3 1507
PRMT5 1582
SNUPN 1602
NOC4L 1606
CRNKL1 1611
EIF4E 1661
PSMB2 1760
PPP2R2A 1788
DDX52 1795
PSME4 1818
DDX42 1823
RPS9 1841
DCPS 1987
POLR2L 2016
CCNH 2048
PSMD7 2084
SNRNP27 2142
DHX16 2202
MT-ND4L 2323
NSUN4 2338
YBX1 2418
TNPO1 2429
PAN3 2462
GPRC5A 2518
QTRT2 2548
WTAP 2606
NUP50 2638
MT-TC 2702
MT-TF 2765
CNOT8 2767
SMNDC1 2779
DUS2 2832
MT-TE 2931
AQR 2936
HSD17B10 2981
MT-TA 2997
CNOT4 3043
HNRNPA2B1 3074
PSMA1 3111
ISG20L2 3150
RBM22 3157
PCF11 3209
GTF2H2 3309
SNW1 3347
MT-TV 3363
MT-TN 3398
ERCC3 3424
SF3B2 3446
SF3B6 3448
SEM1 3454
HNRNPUL1 3467
SF3B4 3527
CSTF3 3626
PSMD13 3766
UTP18 3850
WBP4 3912
CTNNBL1 3970
ZBTB8OS 4008
SKIV2L 4029
RNGTT 4041
DDX49 4083
CDK7 4155
POLR2G 4175
USP39 4209
CNOT1 4249
POLR2F 4256
PSMF1 4259
HNRNPC 4266
NOL12 4277
CDC5L 4279
PSMD3 4297
LSM6 4446
MT-ND4 4493
IGF2BP3 4509
MT-TL1 4517
HNRNPM 4537
PSMC2 4543
TFIP11 4590
PRPF4 4659
YWHAB 4721
PSMC1 4827
SMG5 4864
DHX38 4887
DDX23 4899
PSMC6 4959
SMG8 4994
RAE1 5007
CDC40 5078
CWC25 5092
POLR2E 5109
RPL3L 5150
HNRNPL 5152
PPP2R1A 5189
YWHAZ 5202
PSMA6 5209
ADAT3 5211
PRCC 5229
CTU1 5266
PAPOLA 5344
MT-TY 5373
ZFP36 5429
PPIL6 5450
HNRNPK 5529
ENPP2 5530
EIF4A1 5541
IGF2BP2 5542
CLP1 5591
POLR2J 5598
PSMD8 5687
TXNL4A 5755
NXF1 5811
BUD31 5855
NUP98 5874
SNRNP35 5878
CPSF7 5894
RPL26L1 6001
UBC 6135
GPKOW 6169
GTF2F2 6257
SMG9 6262
EDC3 6343
U2AF1 6360
LSM10 6472
AKT1 6498
ERCC2 6621
ERI1 6679
SART1 6691
GTF2F1 6738
PPP2CA 6806
PSMD12 6820
ETF1 6835
TRMT10A 6917
DCP2 6946
SRSF4 7085
RIOK3 7088
CPSF2 7191
ADAR 7212
CNOT6 7242
PSMD6 7307
CPSF3 7310
SUGP1 7370
PSMB6 7399
SEC13 7506
PSMD5 7646
PCBP1 7665
PSMD11 7775
PSMA7 7840
POLR2A 7852
CD2BP2 8001
PSMB3 8005
HNRNPH2 8018
PSMD2 8139
PSMD1 8184
TRMT6 8246
PSMB5 8265
EFTUD2 8455
APOBEC3B 8459
PSMB7 8460
CSNK1D 8475
ZFP36L1 8478
CNOT3 8550
ZMAT5 8694
SRSF9 8713
PSME3 8716
PSMD9 8766
MAPKAPK2 8852
UPF1 9103
GLE1 9246
CD44 9255
HSPA1A 9341
TSEN34 9433
NUP58 9577
CASC3 9610
EXOSC4 10040
PSMD4 10088
PATL1 10094
TNFSF13 10100
NUP214 10131
ANP32A 10170
POLDIP3 10182
XRN2 10267
THOC5 10316
SMG7 10376
NOP10 10379
RPPH1 10428
EIF4G1 10506
SNORD3A 10596
ACTB 10606
APOBEC3A 10987
TRMT9B 11020
MAPK14 11115
PRKCD 11168


Formation of a pool of free 40S subunits

Formation of a pool of free 40S subunits
391
set Formation of a pool of free 40S subunits
setSize 100
pANOVA 4.05e-38
s.dist -0.746
p.adjustANOVA 6.88e-36



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
RPS2 -9591
RPL4 -9549
EIF3B -9526
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
RPS2 -9591
RPL4 -9549
EIF3B -9526
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
EIF3E -9049
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
RPS16 -8579
RPS14 -8541
RPS10 -8494
EIF1AX -8383
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
EIF3L -8255
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
RPS28 -8083
RPS11 -7975
RPL38 -7968
RPL37 -7861
RPL27 -7810
RPS19 -7806
RPL13 -7671
RPL41 -7561
RPL36 -7493
EIF3H -7091
RPL37A -6833
RPL9 -6821
RPS24 -6818
EIF3M -6817
RPS15 -6703
RPL36AL -6646
RPSA -6629
EIF3J -6448
RPL8 -6101
RPLP1 -6018
EIF3F -5200
EIF3D -5158
EIF3C -4716
RPL28 -3873
FAU -3618
UBA52 -3490
EIF3G -2746
EIF3I -2580
EIF3K -2369
RPL39L -1661
EIF3A -1276
RPS26 -1154
RPS27L -496
RPS4Y1 331
RPS9 1841
RPL3L 5150
RPL26L1 6001


Eukaryotic Translation Elongation

Eukaryotic Translation Elongation
349
set Eukaryotic Translation Elongation
setSize 93
pANOVA 1.44e-37
s.dist -0.767
p.adjustANOVA 2.18e-35



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
EEF1A1 -9751
EEF1B2 -9732
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
EEF1A1 -9751
EEF1B2 -9732
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
EEF1G -9293
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
RPS16 -8579
RPS14 -8541
RPS10 -8494
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
RPS28 -8083
RPS11 -7975
RPL38 -7968
RPL37 -7861
RPL27 -7810
RPS19 -7806
RPL13 -7671
RPL41 -7561
RPL36 -7493
RPL37A -6833
RPL9 -6821
RPS24 -6818
RPS15 -6703
RPL36AL -6646
RPSA -6629
EEF2 -6279
RPL8 -6101
RPLP1 -6018
EEF1A1P5 -5877
EEF1D -5664
RPL28 -3873
FAU -3618
UBA52 -3490
EEF1A2 -3246
RPL39L -1661
RPS26 -1154
RPS27L -496
RPS4Y1 331
RPS9 1841
RPL3L 5150
RPL26L1 6001


Peptide chain elongation

Peptide chain elongation
806
set Peptide chain elongation
setSize 88
pANOVA 5.06e-36
s.dist -0.771
p.adjustANOVA 6.88e-34



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
EEF1A1 -9751
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
EEF1A1 -9751
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
RPS16 -8579
RPS14 -8541
RPS10 -8494
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
RPS28 -8083
RPS11 -7975
RPL38 -7968
RPL37 -7861
RPL27 -7810
RPS19 -7806
RPL13 -7671
RPL41 -7561
RPL36 -7493
RPL37A -6833
RPL9 -6821
RPS24 -6818
RPS15 -6703
RPL36AL -6646
RPSA -6629
EEF2 -6279
RPL8 -6101
RPLP1 -6018
RPL28 -3873
FAU -3618
UBA52 -3490
RPL39L -1661
RPS26 -1154
RPS27L -496
RPS4Y1 331
RPS9 1841
RPL3L 5150
RPL26L1 6001


Selenocysteine synthesis

Selenocysteine synthesis
1058
set Selenocysteine synthesis
setSize 92
pANOVA 1.36e-35
s.dist -0.75
p.adjustANOVA 1.68e-33



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
RPS16 -8579
RPS14 -8541
RPS10 -8494
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
RPS28 -8083
RPS11 -7975
RPL38 -7968
SEPSECS -7958
RPL37 -7861
RPL27 -7810
RPS19 -7806
RPL13 -7671
RPL41 -7561
RPL36 -7493
SECISBP2 -6992
RPL37A -6833
RPL9 -6821
RPS24 -6818
RPS15 -6703
RPL36AL -6646
RPSA -6629
EEFSEC -6493
RPL8 -6101
SARS1 -6044
RPLP1 -6018
PSTK -5710
RPL28 -3873
FAU -3618
UBA52 -3490
RPL39L -1661
RPS26 -1154
RPS27L -496
RPS4Y1 331
RPS9 1841
RPL3L 5150
RPL26L1 6001
SEPHS2 8084


L13a-mediated translational silencing of Ceruloplasmin expression

L13a-mediated translational silencing of Ceruloplasmin expression
587
set L13a-mediated translational silencing of Ceruloplasmin expression
setSize 110
pANOVA 7.55e-35
s.dist -0.678
p.adjustANOVA 8.56e-33



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
EIF4A2 -9593
RPS2 -9591
RPL4 -9549
EIF3B -9526
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
EIF4A2 -9593
RPS2 -9591
RPL4 -9549
EIF3B -9526
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
EIF3E -9049
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
RPS16 -8579
RPS14 -8541
RPS10 -8494
EIF1AX -8383
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
EIF3L -8255
RPL22L1 -8202
EIF4B -8190
RPL35 -8183
RPL15 -8169
RPS28 -8083
RPS11 -7975
RPL38 -7968
RPL37 -7861
RPL27 -7810
RPS19 -7806
RPL13 -7671
RPL41 -7561
RPL36 -7493
EIF3H -7091
RPL37A -6833
RPL9 -6821
RPS24 -6818
EIF3M -6817
RPS15 -6703
RPL36AL -6646
RPSA -6629
EIF3J -6448
RPL8 -6101
RPLP1 -6018
EIF3F -5200
EIF3D -5158
EIF3C -4716
RPL28 -3873
FAU -3618
UBA52 -3490
PABPC1 -2991
EIF3G -2746
EIF3I -2580
EIF3K -2369
RPL39L -1661
EIF2S1 -1649
EIF3A -1276
RPS26 -1154
RPS27L -496
RPS4Y1 331
EIF2S2 554
EIF4E 1661
RPS9 1841
EIF2S3 2500
RPL3L 5150
EIF4A1 5541
RPL26L1 6001
EIF4H 7768
EIF4G1 10506


GTP hydrolysis and joining of the 60S ribosomal subunit

GTP hydrolysis and joining of the 60S ribosomal subunit
433
set GTP hydrolysis and joining of the 60S ribosomal subunit
setSize 111
pANOVA 1.11e-34
s.dist -0.674
p.adjustANOVA 1.16e-32



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
EIF4A2 -9593
RPS2 -9591
RPL4 -9549
EIF3B -9526
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
EIF4A2 -9593
RPS2 -9591
RPL4 -9549
EIF3B -9526
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
EIF3E -9049
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
RPS16 -8579
RPS14 -8541
RPS10 -8494
EIF1AX -8383
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
EIF3L -8255
RPL22L1 -8202
EIF4B -8190
RPL35 -8183
RPL15 -8169
RPS28 -8083
RPS11 -7975
RPL38 -7968
RPL37 -7861
RPL27 -7810
RPS19 -7806
RPL13 -7671
RPL41 -7561
RPL36 -7493
EIF3H -7091
EIF5B -6867
RPL37A -6833
RPL9 -6821
RPS24 -6818
EIF3M -6817
RPS15 -6703
RPL36AL -6646
RPSA -6629
EIF3J -6448
RPL8 -6101
RPLP1 -6018
EIF3F -5200
EIF3D -5158
EIF3C -4716
RPL28 -3873
FAU -3618
UBA52 -3490
EIF3G -2746
EIF3I -2580
EIF3K -2369
RPL39L -1661
EIF2S1 -1649
EIF3A -1276
RPS26 -1154
RPS27L -496
RPS4Y1 331
EIF2S2 554
EIF4E 1661
RPS9 1841
EIF2S3 2500
EIF5 2937
RPL3L 5150
EIF4A1 5541
RPL26L1 6001
EIF4H 7768
EIF4G1 10506


Eukaryotic Translation Termination

Eukaryotic Translation Termination
351
set Eukaryotic Translation Termination
setSize 92
pANOVA 3.3e-34
s.dist -0.734
p.adjustANOVA 3.21e-32



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
RPL35A -9291
N6AMT1 -9282
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
RPS16 -8579
RPS14 -8541
RPS10 -8494
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
RPS28 -8083
GSPT2 -7995
RPS11 -7975
RPL38 -7968
RPL37 -7861
RPL27 -7810
RPS19 -7806
RPL13 -7671
RPL41 -7561
RPL36 -7493
RPL37A -6833
RPL9 -6821
RPS24 -6818
RPS15 -6703
RPL36AL -6646
RPSA -6629
RPL8 -6101
RPLP1 -6018
RPL28 -3873
FAU -3618
UBA52 -3490
TRMT112 -2296
GSPT1 -2025
RPL39L -1661
RPS26 -1154
RPS27L -496
RPS4Y1 331
RPS9 1841
APEH 4945
RPL3L 5150
RPL26L1 6001
ETF1 6835


Viral mRNA Translation

Viral mRNA Translation
1313
set Viral mRNA Translation
setSize 88
pANOVA 6.76e-34
s.dist -0.747
p.adjustANOVA 6.14e-32



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
RPS16 -8579
RPS14 -8541
RPS10 -8494
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
RPS28 -8083
RPS11 -7975
RPL38 -7968
RPL37 -7861
RPL27 -7810
RPS19 -7806
RPL13 -7671
RPL41 -7561
RPL36 -7493
RPL37A -6833
RPL9 -6821
RPS24 -6818
RPS15 -6703
RPL36AL -6646
RPSA -6629
RPL8 -6101
RPLP1 -6018
RPL28 -3873
FAU -3618
UBA52 -3490
GRSF1 -2923
RPL39L -1661
RPS26 -1154
RPS27L -496
RPS4Y1 331
RPS9 1841
RPL3L 5150
RPL26L1 6001
DNAJC3 9831


Cap-dependent Translation Initiation

Cap-dependent Translation Initiation
142
set Cap-dependent Translation Initiation
setSize 118
pANOVA 2.65e-33
s.dist -0.64
p.adjustANOVA 2.12e-31



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
EIF4A2 -9593
RPS2 -9591
RPL4 -9549
EIF3B -9526
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
EIF4A2 -9593
RPS2 -9591
RPL4 -9549
EIF3B -9526
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
EIF3E -9049
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
RPS16 -8579
RPS14 -8541
RPS10 -8494
EIF1AX -8383
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
EIF3L -8255
RPL22L1 -8202
EIF4B -8190
RPL35 -8183
RPL15 -8169
RPS28 -8083
RPS11 -7975
RPL38 -7968
RPL37 -7861
RPL27 -7810
RPS19 -7806
RPL13 -7671
RPL41 -7561
RPL36 -7493
EIF3H -7091
EIF5B -6867
RPL37A -6833
RPL9 -6821
RPS24 -6818
EIF3M -6817
RPS15 -6703
EIF2B3 -6649
RPL36AL -6646
RPSA -6629
EIF3J -6448
RPL8 -6101
RPLP1 -6018
EIF2B5 -5580
EIF3F -5200
EIF3D -5158
EIF3C -4716
RPL28 -3873
FAU -3618
UBA52 -3490
PABPC1 -2991
EIF3G -2746
EIF3I -2580
EIF3K -2369
EIF2B1 -2228
RPL39L -1661
EIF2S1 -1649
EIF3A -1276
RPS26 -1154
RPS27L -496
RPS4Y1 331
EIF2S2 554
EIF4E 1661
RPS9 1841
EIF2S3 2500
EIF4EBP1 2825
EIF5 2937
EIF2B4 4294
RPL3L 5150
EIF4A1 5541
RPL26L1 6001
EIF2B2 7498
EIF4H 7768
EIF4G1 10506


Eukaryotic Translation Initiation

Eukaryotic Translation Initiation
350
set Eukaryotic Translation Initiation
setSize 118
pANOVA 2.65e-33
s.dist -0.64
p.adjustANOVA 2.12e-31



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
EIF4A2 -9593
RPS2 -9591
RPL4 -9549
EIF3B -9526
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
EIF4A2 -9593
RPS2 -9591
RPL4 -9549
EIF3B -9526
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
EIF3E -9049
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
RPS16 -8579
RPS14 -8541
RPS10 -8494
EIF1AX -8383
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
EIF3L -8255
RPL22L1 -8202
EIF4B -8190
RPL35 -8183
RPL15 -8169
RPS28 -8083
RPS11 -7975
RPL38 -7968
RPL37 -7861
RPL27 -7810
RPS19 -7806
RPL13 -7671
RPL41 -7561
RPL36 -7493
EIF3H -7091
EIF5B -6867
RPL37A -6833
RPL9 -6821
RPS24 -6818
EIF3M -6817
RPS15 -6703
EIF2B3 -6649
RPL36AL -6646
RPSA -6629
EIF3J -6448
RPL8 -6101
RPLP1 -6018
EIF2B5 -5580
EIF3F -5200
EIF3D -5158
EIF3C -4716
RPL28 -3873
FAU -3618
UBA52 -3490
PABPC1 -2991
EIF3G -2746
EIF3I -2580
EIF3K -2369
EIF2B1 -2228
RPL39L -1661
EIF2S1 -1649
EIF3A -1276
RPS26 -1154
RPS27L -496
RPS4Y1 331
EIF2S2 554
EIF4E 1661
RPS9 1841
EIF2S3 2500
EIF4EBP1 2825
EIF5 2937
EIF2B4 4294
RPL3L 5150
EIF4A1 5541
RPL26L1 6001
EIF2B2 7498
EIF4H 7768
EIF4G1 10506


Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
742
set Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
setSize 94
pANOVA 1.58e-32
s.dist -0.708
p.adjustANOVA 1.2e-30



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
NCBP2 -9631
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
NCBP2 -9631
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
RPS16 -8579
RPS14 -8541
RPS10 -8494
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
RPS28 -8083
GSPT2 -7995
RPS11 -7975
RPL38 -7968
RPL37 -7861
RPL27 -7810
RPS19 -7806
RPL13 -7671
RPL41 -7561
RPL36 -7493
RPL37A -6833
RPL9 -6821
RPS24 -6818
RPS15 -6703
RPL36AL -6646
RPSA -6629
RPL8 -6101
RPLP1 -6018
RPL28 -3873
FAU -3618
UBA52 -3490
PABPC1 -2991
GSPT1 -2025
RPL39L -1661
RPS26 -1154
NCBP1 -942
RPS27L -496
RPS4Y1 331
RPS9 1841
RPL3L 5150
RPL26L1 6001
ETF1 6835
UPF1 9103
EIF4G1 10506


Response of EIF2AK4 (GCN2) to amino acid deficiency

Response of EIF2AK4 (GCN2) to amino acid deficiency
1006
set Response of EIF2AK4 (GCN2) to amino acid deficiency
setSize 100
pANOVA 3.17e-31
s.dist -0.672
p.adjustANOVA 2.27e-29



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
RPS16 -8579
RPS14 -8541
RPS10 -8494
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
RPS28 -8083
RPS11 -7975
RPL38 -7968
RPL37 -7861
RPL27 -7810
RPS19 -7806
ASNS -7772
RPL13 -7671
RPL41 -7561
RPL36 -7493
RPL37A -6833
RPL9 -6821
RPS24 -6818
RPS15 -6703
RPL36AL -6646
RPSA -6629
RPL8 -6101
RPLP1 -6018
GCN1 -5625
IMPACT -5597
ATF3 -4287
RPL28 -3873
FAU -3618
UBA52 -3490
RPL39L -1661
EIF2AK4 -1656
EIF2S1 -1649
RPS26 -1154
ATF2 -657
RPS27L -496
ATF4 -54
RPS4Y1 331
EIF2S2 554
RPS9 1841
TRIB3 2492
EIF2S3 2500
CEBPG 4210
RPL3L 5150
RPL26L1 6001
DDIT3 6480
CEBPB 11136


Influenza Viral RNA Transcription and Replication

Influenza Viral RNA Transcription and Replication
526
set Influenza Viral RNA Transcription and Replication
setSize 135
pANOVA 5.44e-31
s.dist -0.576
p.adjustANOVA 3.7e-29



Top enriched genes

Top 20 genes
GeneID Gene Rank
IPO5 -10129
NDC1 -10077
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
NUP35 -9726
RPS27A -9723
RPS6 -9699
RPL14 -9698
NUP88 -9668
RPS25 -9664
RPL22 -9659
RPS2 -9591
SEH1L -9574
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IPO5 -10129
NDC1 -10077
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
NUP35 -9726
RPS27A -9723
RPS6 -9699
RPL14 -9698
NUP88 -9668
RPS25 -9664
RPL22 -9659
RPS2 -9591
SEH1L -9574
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
RPS16 -8579
RPS14 -8541
RPS10 -8494
PARP1 -8391
RPL23 -8373
NUP43 -8368
NUP160 -8357
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
NUP107 -8285
RPS17 -8281
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
RPS28 -8083
RPS11 -7975
RPL38 -7968
NUP188 -7953
RPL37 -7861
RPL27 -7810
RPS19 -7806
RPL13 -7671
RPL41 -7561
NUP205 -7516
RPL36 -7493
NUP54 -7131
NUP155 -7061
POLR2D -6856
RPL37A -6833
RPL9 -6821
RPS24 -6818
RPS15 -6703
RPL36AL -6646
RPSA -6629
NUP93 -6458
POLR2H -6200
RPL8 -6101
RPLP1 -6018
NUP133 -5346
POLR2K -4907
NUP42 -4045
HSP90AA1 -4016
NUP210 -3949
POLR2I -3929
RPL28 -3873
TPR -3744
FAU -3618
UBA52 -3490
NUP85 -3427
POLR2B -3384
AAAS -3332
GRSF1 -2923
NUP62 -2410
NUP37 -2275
POM121C -1710
RPL39L -1661
RPS26 -1154
RANBP2 -1141
RPS27L -496
POLR2C -494
POM121 -142
NUP153 254
RPS4Y1 331
RPS9 1841
POLR2L 2016
NUP50 2638
POLR2G 4175
POLR2F 4256
RAE1 5007
POLR2E 5109
RPL3L 5150
POLR2J 5598
NUP98 5874
RPL26L1 6001
GTF2F2 6257
GTF2F1 6738
SEC13 7506
POLR2A 7852
NUP58 9577
DNAJC3 9831
NUP214 10131


Selenoamino acid metabolism

Selenoamino acid metabolism
1057
set Selenoamino acid metabolism
setSize 114
pANOVA 2.44e-30
s.dist -0.62
p.adjustANOVA 1.58e-28



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
LARS1 -9637
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
LARS1 -9637
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
RPL27A -9048
RPS5 -9042
RPL10 -9031
IARS1 -8999
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
RPS16 -8579
RPS14 -8541
RPS10 -8494
KARS1 -8380
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
RPS28 -8083
AIMP1 -7990
RPS11 -7975
RPL38 -7968
SEPSECS -7958
RPL37 -7861
RPL27 -7810
RPS19 -7806
RPL13 -7671
SCLY -7645
RPL41 -7561
RPL36 -7493
SECISBP2 -6992
DARS1 -6939
RPL37A -6833
RPL9 -6821
RPS24 -6818
RPS15 -6703
RPL36AL -6646
RPSA -6629
EEFSEC -6493
EPRS1 -6350
RPL8 -6101
SARS1 -6044
RPLP1 -6018
PSTK -5710
RARS1 -3944
RPL28 -3873
QARS1 -3758
FAU -3618
UBA52 -3490
AIMP2 -3343
EEF1E1 -2716
AHCY -2510
RPL39L -1661
RPS26 -1154
CTH -637
RPS27L -496
INMT -384
RPS4Y1 331
RPS9 1841
GNMT 2920
RPL3L 5150
RPL26L1 6001
HNMT 6423
MARS1 7358
SEPHS2 8084
TXNRD1 9890
PAPSS1 10336
GSR 11051
CBS 11232
PAPSS2 11267


Membrane Trafficking

Membrane Trafficking
629
set Membrane Trafficking
setSize 558
pANOVA 2.21e-28
s.dist 0.273
p.adjustANOVA 1.37e-26



Top enriched genes

Top 20 genes
GeneID Gene Rank
F5 11434
GNS 11410
SERPINA1 11407
PLIN3 11351
AP2A1 11340
CUX1 11300
AMPH 11248
SNX18 11203
RIN1 11169
ULK1 11151
COPG1 11142
SBF2 11135
TBC1D14 11112
VAMP7 11110
DENND3 11024
TGFA 10983
ARPC1A 10981
RAB10 10956
CD55 10914
GALNT2 10885

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
F5 11434
GNS 11410
SERPINA1 11407
PLIN3 11351
AP2A1 11340
CUX1 11300
AMPH 11248
SNX18 11203
RIN1 11169
ULK1 11151
COPG1 11142
SBF2 11135
TBC1D14 11112
VAMP7 11110
DENND3 11024
TGFA 10983
ARPC1A 10981
RAB10 10956
CD55 10914
GALNT2 10885
AP1B1 10872
MAN1A1 10830
SEC24D 10803
BLOC1S1 10801
TBC1D2 10799
RIN2 10772
ITSN1 10737
GRB2 10733
CPD 10712
EPN1 10697
ARRB2 10688
DCTN4 10682
RAB31 10661
DAB2 10645
LDLR 10634
RAB32 10626
RAC1 10624
RAB13 10611
ARF1 10610
RALGAPA2 10588
GJD3 10584
SYNJ1 10567
COPA 10521
HIP1 10519
AGFG1 10514
IGF2R 10494
SORT1 10465
KIF1B 10454
YWHAG 10453
CYTH4 10450
MON1B 10423
TBC1D10B 10419
DCTN2 10412
VPS37C 10402
DNM2 10373
PREB 10364
UBAP1 10354
ACTR1A 10310
TGOLN2 10307
CLTC 10304
PACSIN2 10295
MAN2A2 10274
RAB39A 10255
EXOC6 10253
PICALM 10243
STX10 10228
AP1S1 10225
AP2A2 10223
CHMP2A 10205
TBC1D1 10161
CHMP4B 10154
RAB7A 10115
ARPC5 10102
FTL 10101
REPS2 10081
RAB1B 10055
YWHAH 10050
CHMP5 10034
COG7 9987
RAB1A 9971
RAB6A 9958
CTSZ 9943
CBL 9903
NSF 9870
RAB5C 9864
DENND5A 9804
PLA2G4A 9803
TRAPPC12 9770
BICD2 9707
GRK3 9662
SCARB2 9643
GORASP1 9633
SH3GL1 9632
RAB27A 9628
KDELR1 9613
AP1M1 9595
ARPC4 9592
EXOC7 9580
CAPZB 9575
DCTN1 9558
MYO5A 9548
CAPZA1 9530
KIF1C 9483
LMAN2 9480
ARF3 9465
SEC16A 9460
VPS25 9447
SEC24A 9414
GOLGA2 9412
GRK2 9386
KIF3C 9374
ARF4 9348
OCRL 9323
HGS 9317
VAMP3 9311
VTI1A 9303
CTSC 9276
MYH9 9224
GAK 9209
CLTCL1 9201
TOR1B 9184
PPP6R1 9179
SNAP29 9157
GOLIM4 9092
TRAPPC1 9087
GOLGA1 9075
ARPC2 9016
SEC24C 8993
YWHAE 8971
DENND4B 8934
SEC16B 8899
COPB2 8898
ACTR2 8895
KLC1 8888
ACTR3 8873
RAB3IL1 8870
HPS1 8846
GAPVD1 8844
TOR1A 8807
AP2M1 8799
VPS37A 8762
MVB12B 8734
ARPC3 8726
COPS7A 8712
COPG2 8709
VPS37B 8615
CHMP3 8606
STX5 8547
GGA3 8491
CSNK1D 8475
EPS15L1 8461
KIF13B 8431
NAA38 8425
COG4 8402
RAB36 8383
ARF5 8313
SURF4 8306
DYNC1LI1 8276
RAB5B 8258
EXOC1 8238
COPE 8230
CAPZA2 8225
MIA2 8200
KIF5B 8197
TBC1D13 8195
SYT2 8154
TFG 8124
RABGEF1 8058
AP2S1 8045
TMED9 8028
F8 8026
MAP1LC3B 8019
COPB1 7997
COL7A1 7971
CLTB 7968
AGPAT3 7932
KIAA0319 7910
TSG101 7901
PAFAH1B1 7857
AP3B1 7854
SNAPIN 7826
CHMP6 7813
PRKAG1 7805
GDI1 7789
PIP5K1C 7742
RAB8B 7739
STX6 7734
TRAPPC8 7708
SPTB 7702
GBF1 7683
RIC1 7660
DENND2C 7658
DYNC1LI2 7644
YKT6 7621
NEDD8 7558
DCTN6 7540
SNAP23 7530
GABARAPL2 7529
RAB35 7522
GOLGA5 7519
NAPG 7516
TRAPPC11 7513
SEC13 7506
FNBP1L 7449
ALS2 7445
STAM2 7431
ARFGAP3 7424
AP4M1 7364
RGP1 7355
SEC24B 7352
PUM1 7329
EXOC3 7328
AP1G1 7318
FCHO2 7311
DENND1A 7260
STXBP3 7210
CLTA 7164
RAB5A 7154
PRKAB1 7148
SEC23A 7129
GGA1 7102
GABARAP 7075
TBC1D7 7042
RAB18 7038
STX4 7026
MVB12A 6984
ARCN1 6965
GDI2 6949
SAR1B 6893
FTH1 6883
RAB43 6846
SYT11 6842
YIPF6 6839
KIF9 6805
DYNC1I2 6705
NAPA 6660
DCTN3 6625
RAB11A 6617
RAB3GAP2 6599
ITSN2 6557
TRAPPC9 6548
AKT1 6498
GALNT1 6495
SNX2 6471
EXOC4 6466
KLC3 6451
RABEPK 6419
STX18 6405
KDELR2 6387
VPS53 6373
SCFD1 6297
RAB3A 6284
SEC22B 6272
APP 6245
ANKRD27 6228
RAB21 6196
TMEM115 6183
UBC 6135
RAB7B 6060
EPS15 6059
AP3S1 6030
DNM1 5998
PAFAH1B2 5996
GOSR2 5986
CENPE 5930
NECAP1 5923
TBC1D8B 5919
RACGAP1 5897
ACTR10 5886
SH3KBP1 5885
EXOC8 5853
CCZ1 5832
KIF18B 5806
RABGAP1 5785
DNASE2 5689
ANK1 5655
TBC1D16 5645
TBC1D24 5578
CLINT1 5548
UBQLN2 5531
RAB8A 5522
AKT2 5502
RAB14 5469
SYT1 5438
CCZ1B 5430
SNF8 5420
KIF3B 5396
UBQLN1 5365
TMED2 5345
EGF 5267
YWHAZ 5202
RAB3GAP1 5167
MCFD2 5134
KIF27 5112
RAB33B 5028
AP4E1 5016
STX16 4979
KIF21B 4976
GJC1 4969
VPS4B 4920
FNBP1 4869
VPS54 4853
TFRC 4842
SPTBN5 4732
YWHAB 4721
KIF4A 4526
TRAPPC3 4443
SEC31A 4346
ARFGAP2 4331
TSC2 4311
LRP2 4295
KIF23 4278
CD59 4252
CNIH2 4186
SPTA1 4063
TMED7 3978
GCC1 3975
RAB11B 3969
ARRB1 3956
TBC1D20 3947
VTA1 3940
KIF20A 3824
PPP6R3 3723
COPS5 3579
GJB6 3533
DNM3 3523
FZD4 3498
CHMP4A 3465
AVPR2 3452
TMED3 3420
WASL 3297
VPS52 3262
TRAPPC5 3257
NAPB 3180
MADD 3143
CFTR 3091
CHMP2B 3087
CYTH2 3016
ARF6 3007
ARFGAP1 2978
AP2B1 2910
DYNC1I1 2879
EPN2 2846
TPD52L1 2819
RHOQ 2797
DNAJC6 2611
TRAPPC10 2565
USO1 2424
AREG 2386
DENND1C 2358
COG5 2352
KIF6 2255
TBC1D25 2205
PPP6C 2138
RALGAPB 2083
HBEGF 2064
KIF2C 2011
ACBD3 1983
SNX9 1918
SFN 1840
DYNC1H1 1705
LMAN2L 1586
DYNLL1 1530
RAB41 1488
TMF1 1460
NBAS 1441
TSC1 1403
SNX5 1377
DENND6A 1376
TRAPPC6B 1327
COPS3 1310
TF 1246
CHM 1115
POLG 1085
UBB 1026
KIF19 1011
STON1 956
COPS2 934
STAM 907
KDELR3 869
RAB27B 774
SEC23IP 737
MON1A 707
DENND6B 706
RAB33A 620
VAMP4 607
TBC1D3 561
EXOC5 550
BLOC1S3 547
KIF11 545
CTTN 514
COPZ1 412
COG8 406
USP6NL 325
DCTN5 297
KIFC1 288
VPS4A 169
VAMP8 -139
REPS1 -150
SPTBN2 -220
EREG -249
TJP1 -300
VPS45 -382
KIF18A -394
KIF26A -414
TRAPPC13 -481
RAB3IP -569
AP4B1 -603
ZW10 -627
STON2 -635
GJC2 -694
VPS28 -758
MYO1C -962
FCHO1 -1148
LNPEP -1165
EPGN -1241
COPS6 -1242
CALM1 -1245
GGA2 -1297
RINL -1455
PIK3C2A -1501
KIF15 -1564
BET1L -1574
RAB4A -1669
RAB9A -1713
RAB6B -1849
TRAPPC2L -1855
AP1S3 -1882
PRKAG2 -1916
SYS1 -2040
RAB12 -2139
TXNDC5 -2141
BLOC1S6 -2146
COG3 -2175
BICD1 -2303
GPS1 -2376
TRAPPC4 -2490
DENND4A -2494
CNIH1 -2698
TRIP11 -2705
COPS4 -2731
ARL1 -2770
GOSR1 -3080
ADRB2 -3128
KIFC2 -3136
SEC22C -3143
DENND1B -3163
SBF1 -3176
TBC1D15 -3245
RAB38 -3316
AAK1 -3358
DTNBP1 -3372
AP1G2 -3387
C2CD5 -3422
UBA52 -3490
MYO6 -3522
GOLGA4 -3561
RHOBTB3 -3616
DENND2A -3622
MIA3 -3686
COPS7B -3712
NECAP2 -3755
DENND4C -3756
TBC1D10A -3790
KIFAP3 -3831
GOLGB1 -4004
MAN2A1 -4015
ARFIP2 -4029
PAFAH1B3 -4044
MAN1A2 -4146
RAB9B -4177
AP4S1 -4191
KLC4 -4248
CYTH3 -4278
TBC1D17 -4327
KIF28P -4361
TMED10 -4413
CNIH3 -4435
VPS36 -4497
ARFRP1 -4525
EXOC2 -4563
RABEP1 -4568
KIF16B -4619
YWHAQ -4624
SYTL1 -4650
M6PR -4860
DYNLL2 -4904
CHML -4951
USE1 -5115
KLC2 -5453
PRKAB2 -5520
COG2 -5554
DVL2 -5637
ANKRD28 -5681
COPZ2 -5974
DENND5B -6013
TRIP10 -6094
ASPSCR1 -6098
SH3D19 -6131
BLOC1S4 -6160
BNIP1 -6184
SLC2A8 -6202
AP1M2 -6253
BET1 -6342
RALA -6392
SRC -6396
GCC2 -6501
HPS4 -6635
COG6 -6645
NAA35 -6750
KIF21A -6834
KIF2A -6844
CD4 -6881
KIF5A -6961
TRAPPC2 -7043
COG1 -7045
PLA2G6 -7168
KIF20B -7260
KIF26B -7360
NAA30 -7523
TBC1D10C -7608
ANK3 -7751
SEC22A -7808
STX17 -8013
CD3G -8111
SPTBN1 -8138
VPS51 -8242
CD3D -8297
RAB39B -8372
OPTN -8400
LMAN1 -8522
HIP1R -8608
RAB30 -8666
VAMP2 -8673
TPD52 -8806
AKT3 -8810
COPS8 -8830
AP1S2 -8979
RINT1 -8985
CYTH1 -9019
CHMP7 -9039
SCOC -9113
HSPA8 -9129
BIN1 -9243
SYNJ2 -9322
DENND2D -9419
KIF3A -9438
SPTAN1 -9461
TRAPPC6A -9543
PACSIN1 -9553
RPS27A -9723
KIF22 -9850
MAN1C1 -9944
LDLRAP1 -10002
ALS2CL -10013
TBC1D4 -10097
KIF5C -10128
IL7R -10153


Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
741
set Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
setSize 114
pANOVA 1.63e-27
s.dist -0.588
p.adjustANOVA 9.23e-26



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
NCBP2 -9631
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
NCBP2 -9631
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
UPF3A -8795
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
RPS16 -8579
RPS14 -8541
RPS10 -8494
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
RPS28 -8083
RNPS1 -8030
GSPT2 -7995
RPS11 -7975
RPL38 -7968
RPL37 -7861
RPL27 -7810
RPS19 -7806
RPL13 -7671
RPL41 -7561
RPL36 -7493
RPL37A -6833
RPL9 -6821
RPS24 -6818
MAGOHB -6726
RPS15 -6703
RPL36AL -6646
RPSA -6629
RPL8 -6101
RPLP1 -6018
UPF3B -5843
DCP1A -4839
MAGOH -4678
RPL28 -3873
PNRC2 -3729
FAU -3618
UBA52 -3490
PABPC1 -2991
GSPT1 -2025
RPL39L -1661
RBM8A -1499
RPS26 -1154
NCBP1 -942
RPS27L -496
SMG1 -489
SMG6 -480
RPS4Y1 331
UPF2 1281
EIF4A3 1507
PPP2R2A 1788
RPS9 1841
SMG5 4864
SMG8 4994
RPL3L 5150
PPP2R1A 5189
RPL26L1 6001
SMG9 6262
PPP2CA 6806
ETF1 6835
UPF1 9103
CASC3 9610
SMG7 10376
EIF4G1 10506


Nonsense-Mediated Decay (NMD)

Nonsense-Mediated Decay (NMD)
743
set Nonsense-Mediated Decay (NMD)
setSize 114
pANOVA 1.63e-27
s.dist -0.588
p.adjustANOVA 9.23e-26



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
NCBP2 -9631
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
NCBP2 -9631
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
UPF3A -8795
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
RPS16 -8579
RPS14 -8541
RPS10 -8494
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
RPS28 -8083
RNPS1 -8030
GSPT2 -7995
RPS11 -7975
RPL38 -7968
RPL37 -7861
RPL27 -7810
RPS19 -7806
RPL13 -7671
RPL41 -7561
RPL36 -7493
RPL37A -6833
RPL9 -6821
RPS24 -6818
MAGOHB -6726
RPS15 -6703
RPL36AL -6646
RPSA -6629
RPL8 -6101
RPLP1 -6018
UPF3B -5843
DCP1A -4839
MAGOH -4678
RPL28 -3873
PNRC2 -3729
FAU -3618
UBA52 -3490
PABPC1 -2991
GSPT1 -2025
RPL39L -1661
RBM8A -1499
RPS26 -1154
NCBP1 -942
RPS27L -496
SMG1 -489
SMG6 -480
RPS4Y1 331
UPF2 1281
EIF4A3 1507
PPP2R2A 1788
RPS9 1841
SMG5 4864
SMG8 4994
RPL3L 5150
PPP2R1A 5189
RPL26L1 6001
SMG9 6262
PPP2CA 6806
ETF1 6835
UPF1 9103
CASC3 9610
SMG7 10376
EIF4G1 10506


Immune System

Immune System
517
set Immune System
setSize 1893
pANOVA 2.18e-27
s.dist 0.15
p.adjustANOVA 1.19e-25



Top enriched genes

Top 20 genes
GeneID Gene Rank
SLC11A1 11464
CSF2RA 11457
TRIM71 11456
NCSTN 11452
C1QC 11448
C1QB 11445
DOK3 11443
P2RX1 11442
LILRB2 11437
HK3 11430
OSCAR 11425
LILRA6 11421
IL1R2 11419
IDH1 11418
SIRPA 11414
GNS 11410
LILRA5 11408
SERPINA1 11407
CR1 11401
DNASE1L1 11385

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All member genes
GeneID Gene Rank
SLC11A1 11464.0
CSF2RA 11457.0
TRIM71 11456.0
NCSTN 11452.0
C1QC 11448.0
C1QB 11445.0
DOK3 11443.0
P2RX1 11442.0
LILRB2 11437.0
HK3 11430.0
OSCAR 11425.0
LILRA6 11421.0
IL1R2 11419.0
IDH1 11418.0
SIRPA 11414.0
GNS 11410.0
LILRA5 11408.0
SERPINA1 11407.0
CR1 11401.0
DNASE1L1 11385.0
SIGLEC9 11381.0
QSOX1 11369.0
PRKACA 11363.0
LILRB5 11361.0
CD63 11355.0
MYO10 11353.0
MCEMP1 11349.0
LILRB4 11348.0
RASGRP4 11346.0
AP2A1 11340.0
CD300C 11335.0
SIGLEC10 11334.0
MYD88 11331.0
WASF1 11328.0
BCL6 11324.0
FGR 11323.0
C1QA 11320.0
HP 11312.0
NCKAP1L 11304.0
IMPDH1 11303.0
CTSD 11297.0
C3AR1 11294.0
MAP3K8 11291.0
STXBP2 11285.0
ATP6V0A1 11283.0
RHOU 11282.0
LAIR1 11276.0
TIMP1 11275.0
ITGAM 11269.0
UNC13D 11266.0
IFNGR2 11265.0
ICAM5 11254.0
CTSB 11250.0
MAPKAPK3 11249.0
NLRC4 11239.0
ITGAX 11231.0
ANPEP 11227.0
FPR1 11221.0
FBXO9 11219.0
FCER1G 11216.0
TIMP2 11214.0
S100A12 11206.0
HCK 11202.0
MAPK1 11193.0
RNASE2 11192.0
TLR5 11191.0
CASP9 11186.0
PTK2B 11185.0
S100A8 11184.0
ALOX5 11178.0
GUSB 11175.0
PRKCD 11168.0
MMP2 11162.0
KLHL2 11154.0
IL10 11149.0
IL17RA 11148.0
TCIRG1 11138.0
TRPM2 11134.0
PGAM1 11128.0
IL10RB 11122.0
PLAC8 11120.0
MAPK14 11115.0
VAMP7 11110.0
RPS6KA1 11103.0
IFI27 11095.0
PLD1 11091.0
TRIM25 11088.0
NEU1 11082.0
SERPINB1 11081.0
NKIRAS2 11077.0
ACAA1 11076.0
PTPN9 11075.0
CD177 11068.0
ALDH3B1 11063.0
C5AR1 11061.0
MMP25 11057.0
AGPAT2 11054.0
PLEKHO2 11053.0
MEFV 11043.0
HMOX1 11030.0
ADGRG3 11019.0
ATP6V0D1 11016.0
RIPK3 11013.0
VNN1 11000.0
GCA 10999.0
VIM 10996.0
ATP6V0C 10995.0
RNF135 10992.0
TNFRSF1A 10988.0
TGFA 10983.0
ARPC1A 10981.0
IL27 10978.0
EIF4G3 10977.0
FBXL19 10975.0
VAT1 10971.0
ADAM17 10964.0
BRI3 10962.0
MAP2K6 10958.0
RAB10 10956.0
PYGL 10952.0
MGAM 10950.0
CD36 10947.0
CD93 10937.0
MOSPD2 10933.0
CEACAM3 10932.0
PVR 10924.0
MMP9 10920.0
LMNB1 10917.0
PTPN18 10915.0
CD55 10914.0
S100A11 10910.0
IRAK3 10909.0
NFAM1 10890.0
FPR2 10883.0
PIK3AP1 10882.0
LTBR 10880.0
MX2 10877.0
IL1RN 10874.0
GYG1 10873.0
AP1B1 10872.0
ALDOA 10868.0
ITGB2 10861.0
CDA 10859.0
TREML4 10857.0
RGL3 10853.0
TRAF7 10851.0
BTK 10849.0
CLEC4G 10848.0
TLR8 10847.0
GM2A 10846.0
WSB1 10845.0
CTSA 10842.0
GRN 10837.0
ALPK1 10833.0
MYO9B 10832.0
LILRB1 10829.0
TYK2 10828.0
SOCS3 10826.0
CKAP4 10819.0
RNASEL 10818.0
NLRX1 10815.0
CRISPLD2 10814.0
NCF4 10813.0
CLU 10812.0
LYN 10810.0
WASF2 10807.0
SEC24D 10803.0
ASAH1 10796.0
NCF2 10793.0
IL1R1 10792.0
ATP11A 10791.0
MARK3 10787.0
LRG1 10785.0
ARPC1B 10781.0
INPPL1 10780.0
WAS 10777.0
CYB5R3 10775.0
TSPAN14 10759.0
RGL1 10752.0
NBEAL2 10743.0
GRB2 10733.0
RETN 10732.0
SLC2A3 10714.0
SERPINB2 10710.0
ANXA2 10704.0
TRIM8 10701.0
QPCT 10700.0
C2 10689.0
ARRB2 10688.0
SLC15A4 10684.0
DCTN4 10682.0
RAB3D 10677.0
C5AR2 10670.0
RAB31 10661.0
LAT2 10657.0
BST1 10647.0
RHOG 10635.0
GPR84 10632.0
IFNGR1 10627.0
RAC1 10624.0
PTPN1 10623.0
APBB1IP 10622.0
CD300E 10618.0
SIGLEC16 10616.0
S100A9 10613.0
ARF1 10610.0
ACTB 10606.0
CYSTM1 10605.0
GLA 10595.0
TOM1 10594.0
LRRC41 10583.0
KSR1 10576.0
CAPN1 10570.0
AREL1 10569.0
GSN 10558.0
TNFAIP6 10555.0
CD68 10546.0
CEBPD 10543.0
LTA4H 10541.0
PYCARD 10540.0
TLR2 10535.0
GAB2 10528.0
UNC93B1 10526.0
PKM 10523.0
EIF4G1 10506.0
SPRED2 10499.0
IGF2R 10494.0
LILRA2 10491.0
PLAUR 10490.0
CSF3R 10480.0
FCGR2A 10470.0
IFITM2 10469.0
LILRA1 10456.0
PSTPIP1 10451.0
ALAD 10449.0
PTPN6 10446.0
MAP3K3 10435.0
LILRB3 10433.0
PSEN1 10429.0
PITPNA 10422.0
CYFIP1 10420.0
HGF 10417.0
HAVCR2 10416.0
PECAM1 10414.0
DCTN2 10412.0
CLEC4D 10398.0
TALDO1 10395.0
CRK 10387.0
PGM2 10380.0
MAP2K3 10377.0
MAP3K11 10375.0
DNM2 10373.0
IL4R 10372.0
DNAJC5 10371.0
FBXW2 10370.0
UBE2R2 10366.0
CD300A 10362.0
ASB1 10342.0
PTPRJ 10340.0
COTL1 10333.0
LCP1 10315.0
IFI30 10311.0
ACTR1A 10310.0
CD53 10308.0
CLTC 10304.0
CTSL 10288.0
VASP 10286.0
RNF41 10276.0
ACLY 10268.0
SYK 10256.0
PADI2 10252.0
KIR2DL3 10251.0
PLCG2 10244.0
VAV1 10226.0
AP1S1 10225.0
AP2A2 10223.0
RNF144B 10221.0
FCAR 10219.0
GLB1 10217.0
RAPGEF2 10206.0
TMBIM1 10197.0
SIGLEC15 10194.0
TLN1 10191.0
ELMO2 10190.0
PTAFR 10188.0
STX3 10186.0
AMPD3 10183.0
CYBA 10173.0
STIM1 10169.0
DOCK2 10155.0
NECTIN2 10150.0
MAP2K1 10148.0
NAPRT 10133.0
NUP214 10131.0
RAB7A 10115.0
CAT 10103.0
ARPC5 10102.0
FTL 10101.0
TNFSF13 10100.0
P4HB 10093.0
PSMD4 10088.0
FBXL5 10086.0
TNFRSF1B 10079.0
ARG1 10061.0
TLR1 10059.0
ARL8A 10056.0
PAK1 10043.0
ARSB 10041.0
IQGAP1 10037.0
MAPK7 10035.0
PDGFRA 10015.0
ADAM10 9992.0
CPPED1 9991.0
SIGLEC7 9990.0
NOD2 9983.0
ATP6V1D 9982.0
SELL 9974.0
TRIP12 9970.0
RAB6A 9958.0
LGALS9 9955.0
UBE2F 9951.0
SDCBP 9947.0
CTSZ 9943.0
CAP1 9934.0
RNF123 9932.0
DNAJC13 9921.0
S100P 9918.0
MSN 9917.0
IGLV7-43 9914.0
PPP2R5B 9913.0
RGL2 9912.0
CBL 9903.0
ATP6V1C1 9900.0
JAK3 9899.0
MEF2A 9891.0
RAB5C 9864.0
STAT6 9852.0
MGST1 9847.0
LRSAM1 9843.0
CDC34 9836.0
DNAJC3 9831.0
PPP2R5A 9827.0
UBA1 9819.0
DBNL 9815.0
TREML2 9814.0
DLG4 9813.0
FOXO3 9800.0
CFL1 9794.0
EP300 9789.0
TEC 9787.0
ATP6V0B 9782.0
MAOA 9761.0
MAPK3 9750.0
SOS2 9744.0
TNFRSF8 9741.0
STAT3 9739.0
BIN2 9720.0
BTNL8 9715.0
LAMP1 9712.0
IFNAR1 9706.0
ARHGAP9 9702.0
CD58 9688.0
RAF1 9686.0
TOLLIP 9682.0
ACTG1 9678.0
NEDD4 9677.0
HSPA6 9675.0
MGRN1 9672.0
CTNNB1 9670.0
CYBB 9660.0
MAPK13 9645.0
TYROBP 9637.0
VAPA 9635.0
RAB24 9634.0
GRIN2D 9631.0
RAB27A 9628.0
CSF1R 9627.0
FLT3 9618.0
MRAS 9617.0
HECW2 9607.0
CCR2 9605.0
AP1M1 9595.0
ARPC4 9592.0
IGKV1-39 9590.0
EIF4E3 9578.0
NUP58 9577.0
CAPZB 9575.0
FBXL18 9559.0
DCTN1 9558.0
TLR4 9549.0
MYO5A 9548.0
PTEN 9545.0
SHC1 9541.0
ATP6V1A 9534.0
CAPZA1 9530.0
PPL 9517.0
JAML 9516.0
KL 9509.0
ZDHHC9 9508.0
CCR1 9507.0
CSTB 9479.0
EBI3 9478.0
UBE2J1 9476.0
CD14 9466.0
GMFG 9443.0
IKBKG 9441.0
ATP6V1B2 9436.0
IRS2 9427.0
CSF2RB 9423.0
SEC24A 9414.0
HECTD3 9408.0
RHOA 9401.0
CSK 9400.0
CAB39 9379.0
FCGR3A 9377.0
KIF3C 9374.0
ABI1 9373.0
UBE2A 9364.0
RNF182 9350.0
DERA 9344.0
HSPA1A 9341.0
CXCR1 9335.0
TRIM41 9327.0
LY96 9322.0
VPS35L 9320.0
RILP 9316.0
VAMP3 9311.0
UBE2D1 9286.0
SP100 9281.0
CTSC 9276.0
TXN 9268.0
LAMTOR1 9265.0
CANT1 9259.0
CD44 9255.0
MICB 9248.0
IFNAR2 9244.0
SIGLEC5 9235.0
MYH9 9224.0
TNFRSF12A 9200.0
GSTO1 9188.0
LGALS3 9180.0
PTPN2 9173.0
SNAP29 9157.0
CNN2 9140.0
PIK3CB 9126.0
DTX4 9123.0
PELI3 9118.0
RAPGEF3 9100.0
NEDD4L 9088.0
TRAPPC1 9087.0
UBE2H 9080.0
PILRA 9071.0
TLR6 9070.0
SAMHD1 9062.0
CEACAM1 9052.0
GALNS 9046.0
PAK2 9042.0
LAMP2 9034.0
INPP5D 9020.0
ARPC2 9016.0
PDAP1 9011.0
HIF1A 9002.0
IST1 8994.0
SEC24C 8993.0
STK10 8992.0
FBXL13 8980.0
CMTM6 8960.0
PIK3CD 8956.0
NLRP3 8955.0
IL1RAP 8946.0
ADAM8 8938.0
ADGRE5 8937.0
H3C15 8929.5
ACTR2 8895.0
PSAP 8894.0
MNDA 8892.0
PLD2 8890.0
KLC1 8888.0
TICAM1 8878.0
CFP 8875.0
ACTR3 8873.0
STK11IP 8872.0
NCKAP1 8861.0
TIRAP 8858.0
MAPKAPK2 8852.0
MAPK10 8849.0
LONRF1 8847.0
HPSE 8832.0
FKBP1A 8827.0
APAF1 8822.0
HSPA1B 8806.0
LRRFIP1 8804.0
AP2M1 8799.0
FADD 8785.0
PSMD9 8766.0
STAT5B 8742.0
ARPC3 8726.0
CHUK 8723.0
PSME3 8716.0
PDPK1 8710.0
MMP8 8706.0
UBAC1 8704.0
WIPF2 8699.0
ROCK1 8695.0
CREG1 8692.0
CD300LD 8680.0
RNF130 8679.0
GAB1 8670.0
UBE2D3 8641.0
PJA2 8626.0
GAA 8625.0
TNFSF14 8623.0
MVP 8603.0
SIPA1 8599.0
TRIM34 8585.0
PRKCB 8577.0
TANK 8576.0
HEBP2 8559.0
ATP11B 8523.0
FCGR1A 8520.0
PRCP 8518.0
DUSP3 8510.0
NPEPPS 8507.0
OSM 8499.0
CLEC5A 8487.0
SLCO4C1 8486.0
RBCK1 8466.0
DDOST 8464.0
PSMB7 8460.0
ARSA 8456.0
RAB4B 8449.0
TUBB4B 8440.0
IQGAP2 8437.0
ATP6V0E1 8417.0
IL19 8416.0
VAV3 8413.0
KCMF1 8403.0
CLEC4E 8358.0
ORAI2 8345.0
CDC42 8342.0
OSTF1 8338.0
FLNA 8318.0
SURF4 8306.0
IRF2 8298.0
DYNC1LI1 8276.0
TNFSF12 8273.0
PDXK 8267.0
PSMB5 8265.0
IKBKE 8263.0
RAB5B 8258.0
PANX1 8253.0
RAC2 8237.0
CAPZA2 8225.0
CA1 8217.0
ATP6V1E1 8198.0
KIF5B 8197.0
TRIM9 8191.0
PRKCE 8190.0
PSMD1 8184.0
NF1 8146.0
CREBBP 8143.0
PSMD2 8139.0
MAVS 8131.0
FBXO11 8126.0
IFITM3 8102.0
CD300LF 8077.0
MRC1 8063.0
LIMK1 8062.0
AP2S1 8045.0
PNP 8043.0
PTPRC 8021.0
LAMTOR2 8006.0
PSMB3 8005.0
KEAP1 7998.0
COPB1 7997.0
STOM 7990.0
IRAK1 7970.0
RNASET2 7961.0
FCN1 7954.0
FLNB 7929.0
PGLYRP2 7911.0
CLEC6A 7906.0
FABP5 7903.0
SMARCA4 7879.0
SIGLEC12 7871.0
POU2F1 7849.0
ITGAV 7847.0
PSMA7 7840.0
STAT5A 7833.0
DUSP1 7831.0
TREM1 7815.0
TNIP2 7810.0
VCP 7804.0
C4B 7784.0
CARD9 7777.0
FBXL20 7776.0
PSMD11 7775.0
B4GALT1 7763.0
PPM1B 7761.0
MAP2K4 7754.0
UBR2 7749.0
UBA3 7741.0
PTPN12 7724.0
ITPR2 7716.0
CALR 7713.0
SPTB 7702.0
FRS3 7701.0
LPCAT1 7696.0
HEXB 7695.0
MANBA 7689.0
IL18R1 7674.0
RET 7671.0
KBTBD7 7650.0
PSMD5 7646.0
DYNC1LI2 7644.0
OLFM4 7638.0
RAP2C 7598.0
DOCK1 7594.0
FAF2 7588.0
CNPY3 7565.0
DCTN6 7540.0
IL6R 7534.0
SNAP23 7530.0
SEC13 7506.0
TNFSF13B 7501.0
SEC61A1 7486.0
CFB 7474.0
RNF7 7458.0
PPP2CB 7451.0
CD1D 7448.0
ELOB 7435.0
PIM1 7419.0
REL 7415.0
RAP1GAP 7405.0
UBE2M 7401.0
PSMB6 7399.0
BCL10 7391.0
ITGA2B 7387.0
FBXO40 7369.0
ICAM4 7365.0
SEC24B 7352.0
RLIM 7346.0
RAP1A 7335.0
UBE2L3 7330.0
AP1G1 7318.0
RASGRF1 7314.0
CLEC4A 7313.0
TRIM5 7312.0
PSMD6 7307.0
YPEL5 7288.0
SOD2 7284.0
UBE2J2 7267.0
JUNB 7257.0
NCF1 7245.0
CRCP 7239.0
PGM1 7238.0
GGH 7233.0
MAP2K2 7222.0
ADAR 7212.0
IL18RAP 7209.0
VRK3 7206.0
CLTA 7164.0
PTPN23 7161.0
COMMD9 7156.0
SIAH2 7137.0
SIRPB1 7136.0
SEC23A 7129.0
DIAPH1 7128.0
GPI 7117.0
AHCYL1 7116.0
ATP6V1H 7104.0
CXCL1 7072.0
UBE3B 7047.0
RAB18 7038.0
TMEM30A 7030.0
HSPA5 7027.0
STX4 7026.0
RNF111 7005.0
PIAS1 6991.0
LYPLA1 6982.0
ELOC 6974.0
PTPN22 6966.0
RAP1B 6962.0
IRF5 6956.0
GDI2 6949.0
RANBP9 6938.0
CD33 6932.0
DYNLT1 6926.0
ZBTB16 6902.0
SAR1B 6893.0
FTH1 6883.0
OASL 6859.0
NFKBIB 6845.0
CASP4 6841.0
C6orf120 6840.0
RNF19B 6836.0
PRKCSH 6831.0
PSMD12 6820.0
PPP2CA 6806.0
ASB4 6804.0
FCGR1B 6799.0
PDGFRB 6793.0
TAPBP 6757.0
ITCH 6755.0
PPP1CB 6745.0
IGLV10-54 6741.0
CXCR2 6720.0
METTL7A 6718.0
DYNC1I2 6705.0
HBB 6697.0
CGAS 6692.0
CTF1 6678.0
EIF4G2 6666.0
TAB3 6655.0
DCTN3 6625.0
RNASE6 6610.0
FGFR1 6607.0
PPP2R5D 6601.0
UBR4 6594.0
MKRN1 6583.0
CD46 6547.0
PTPN11 6524.0
ATOX1 6512.0
PIK3R2 6511.0
CTSS 6504.0
AKT1 6498.0
SMURF1 6481.0
KIR2DL4 6476.0
FUCA1 6469.0
KLC3 6451.0
C4BPA 6442.0
MUC5B 6394.0
TRIM6 6370.0
KCNAB2 6369.0
HERC3 6350.0
PLD3 6346.0
PIGR 6337.0
MUC16 6329.0
UBE4A 6293.0
MAP3K1 6286.0
RAB3A 6284.0
SEC22B 6272.0
RASA1 6250.0
APP 6245.0
BRAP 6218.0
MCL1 6210.0
CUL3 6200.0
ICAM3 6195.0
VCL 6193.0
LRMP 6184.0
PELI2 6164.0
UBC 6135.0
KRAS 6132.0
ABL1 6127.0
PPP3CB 6126.0
SHOC2 6108.0
ARAF 6089.0
ATG7 6082.0
UBE2W 6055.0
PAG1 6054.0
TRIM14 6031.0
FUCA2 6028.0
DNM1 5998.0
PAFAH1B2 5996.0
RASAL2 5992.0
CUL7 5972.0
ATP7A 5970.0
NDUFC2 5943.0
WDR83 5940.0
CENPE 5930.0
RACGAP1 5897.0
ASB8 5895.0
ACTR10 5886.0
SH3KBP1 5885.0
CSNK2B 5876.0
NUP98 5874.0
CD99 5848.0
MAN2B1 5768.0
IL27RA 5756.0
FBXL4 5725.0
KPNA4 5698.0
PSMD8 5687.0
OPRD1 5678.0
STBD1 5663.0
SIGLEC14 5662.0
VEGFA 5648.0
UBE3C 5633.0
SERPINB10 5629.0
FBXW11 5621.0
KPNB1 5604.0
EIF2AK2 5594.0
IL18 5580.0
UBE2Q1 5579.0
PPP3R1 5564.0
EIF4A1 5541.0
CDKN1A 5537.0
TGFB1 5504.0
AKT2 5502.0
RAB14 5469.0
NFKBIA 5457.0
ELMO1 5455.0
FBXW5 5443.0
KCTD6 5411.0
KIF3B 5396.0
LAMTOR3 5383.0
PDGFA 5341.0
CTSK 5320.0
EIF4E2 5295.0
SERPINB6 5280.0
EGF 5267.0
TAX1BP1 5257.0
ATP8B4 5252.0
CRKL 5250.0
ANXA1 5228.0
GBP6 5223.0
PSMA6 5209.0
YWHAZ 5202.0
PPP2R1A 5189.0
SLC44A2 5180.0
TRIM10 5177.0
DGAT1 5173.0
UBE2K 5166.0
RNF14 5141.0
POLR2E 5109.0
RAPGEF1 5102.0
UBOX5 5090.0
PRDX6 5085.0
IFI6 5040.0
FBXO6 5033.0
SRP14 5022.0
ASB6 5017.0
NHLRC3 5010.0
RAE1 5007.0
CTSH 4985.0
ERAP2 4984.0
TKFC 4982.0
UBA6 4974.0
BCL2L1 4964.0
PSMC6 4959.0
PTPRA 4955.0
TREML1 4952.0
APEH 4945.0
PDZD11 4944.0
ATP6AP2 4915.0
PGLYRP1 4910.0
NRAS 4907.0
PDE6D 4902.0
AGER 4895.0
CD300LB 4879.0
TBK1 4856.0
PTPRN2 4854.0
PSMC1 4827.0
ERP44 4818.0
PELI1 4802.0
UBE2S 4773.0
C1R 4765.0
TRIM21 4745.0
SPTBN5 4732.0
YWHAB 4721.0
IGKV5-2 4704.0
TRIM38 4697.0
SOCS1 4688.0
GLIPR1 4675.0
TRAF6 4673.0
CDC20 4670.0
C5 4661.0
OTUD5 4604.0
CLEC7A 4602.0
ARMC8 4598.0
MAPKAP1 4588.0
PSMC2 4543.0
BIRC5 4541.0
KIF4A 4526.0
MUC1 4458.0
IGLV2-11 4439.0
RNF217 4431.0
HERC4 4429.0
JAK2 4428.0
CASP3 4426.0
FBXO30 4415.0
IRF8 4385.0
RPS6KA2 4384.0
BRAF 4367.0
SIGLEC1 4365.0
NFASC 4356.0
SEC31A 4346.0
MAGT1 4339.0
SEC61B 4322.0
FBXO7 4309.0
SPSB2 4305.0
PSMD3 4297.0
KIF23 4278.0
TICAM2 4262.0
KLHL21 4260.0
PSMF1 4259.0
POLR2F 4256.0
CD59 4252.0
PROS1 4191.0
SIGLEC11 4180.0
ITLN1 4168.0
NF2 4139.0
IRF7 4132.0
PDIA3 4101.0
UBE2B 4086.0
SPTA1 4063.0
SUMO1 4061.0
BATF 4052.0
MAP3K7 4043.0
NOS1 4024.0
IL17C 3994.0
FZR1 3967.0
RBX1 3957.0
ARRB1 3956.0
TARM1 3952.0
UBE2G1 3951.0
IGLC3 3928.0
RAP2B 3915.0
PLAU 3907.0
ANAPC11 3904.0
TNFRSF9 3887.0
VWF 3870.0
POMC 3862.0
TRIM26 3844.0
KIF20A 3824.0
BOLA2 3823.0
ATP6V1F 3811.0
IL33 3789.0
PSMD13 3766.0
LCP2 3759.0
MMP1 3753.0
P2RX7 3740.0
IGKV1D-39 3734.0
CXCL2 3656.0
ITGAL 3647.0
ENAH 3578.0
UBE2C 3555.0
STX1A 3540.0
PPP3CA 3538.0
SPRED1 3532.0
RCHY1 3528.0
KLHL9 3525.0
DNM3 3523.0
IFI35 3478.0
KIR3DL1 3471.0
SEM1 3454.0
ANO6 3404.0
NANOG 3382.0
OSBPL1A 3364.0
CANX 3332.0
NPC2 3326.0
C1S 3306.0
WASL 3297.0
HTN1 3261.0
POLR3A 3224.0
RIPK1 3206.0
RASGEF1A 3199.0
DTX3L 3140.0
WIPF1 3137.0
DEGS1 3135.0
JUN 3122.0
PSMA1 3111.0
FSCN1 3098.0
TXLNA 3083.0
HNRNPA2B1 3074.0
ABHD17C 3057.0
C4A 3032.0
ITGB5 2998.0
CPNE3 2985.0
HLA-C 2969.0
ITGB3 2944.0
AP2B1 2910.0
CASP1 2896.0
DYNC1I1 2879.0
SIAH1 2866.0
NFKB1 2860.0
TNFSF9 2810.0
SPSB1 2791.0
FOS 2787.0
SH3RF1 2766.0
VAV2 2755.0
FOLR3 2736.0
COL1A2 2707.0
TRIM36 2706.0
BIRC2 2697.0
PIK3R3 2676.0
PRKG1 2673.0
FRK 2672.0
TNFRSF11A 2671.0
NUP50 2638.0
VHL 2627.0
RNF114 2590.0
ATF1 2556.0
GAN 2551.0
FBXO41 2546.0
LPO 2539.0
MUC6 2538.0
CAMK2G 2528.0
AOC1 2506.0
TRIB3 2492.0
KBTBD6 2491.0
ASB7 2446.0
DDX41 2414.0
AREG 2386.0
RELB 2367.0
IL1RL1 2334.0
CLEC12A 2330.0
NDN 2322.0
ECSIT 2321.0
LCN2 2300.0
CLEC4C 2219.0
HECTD1 2173.0
EPPIN 2149.0
PIK3CA 2133.0
CDK13 2118.0
SPRED3 2117.0
OSMR 2089.0
PSMD7 2084.0
ORM1 2075.0
HBEGF 2064.0
HLA-E 2060.0
IGKV1-17 2037.0
CASP2 2017.0
POLR2L 2016.0
KIF2C 2011.0
UBR1 1994.0
TAB2 1975.0
OAS1 1937.0
UNKL 1936.0
FNTB 1909.0
GHDC 1853.0
XRCC5 1832.0
PSME4 1818.0
IRF9 1810.0
MTOR 1777.0
PSMB2 1760.0
IKBKB 1759.0
VTN 1756.0
TAB1 1754.0
CST3 1747.0
ULBP3 1706.0
DYNC1H1 1705.0
POLR1D 1703.0
DDX3X 1692.0
DLG2 1666.0
EIF4E 1661.0
FBXL15 1627.0
MT2A 1595.0
IFI16 1590.0
HLA-G 1578.0
PTX3 1567.0
MAP2K7 1550.0
DYNLL1 1530.0
EIF4A3 1507.0
IL13RA1 1505.0
F13A1 1493.0
FCER2 1492.0
CRISP3 1416.0
FCGR3B 1391.0
TRIM11 1357.0
HNRNPF 1319.0
ADGRE3 1240.0
HUWE1 1218.0
CRACR2A 1215.0
BTN2A1 1201.0
RBSN 1171.0
LY86 1163.0
ICAM1 1122.0
ARIH1 1077.0
UBB 1026.0
CASP10 1005.0
PSMD14 941.0
PSMC3 916.0
FBXO15 898.0
MADCAM1 879.0
RASA2 864.0
SYNGR1 852.0
MLEC 796.0
LAMA5 751.0
HLA-DRB5 748.0
MME 695.0
RPS6KA3 649.0
PSMB4 642.0
IGHV1-46 618.0
PSMC4 605.0
ERBB3 599.0
PIN1 577.0
ORM2 565.0
KIF11 545.0
PPP1CC 519.0
GHR 518.0
PTPN14 506.0
ANAPC7 498.0
CFD 461.0
FCGR2B 446.0
PTGS2 444.0
OPRM1 433.0
PTK2 388.0
ZNRF1 372.0
GSDMD 370.0
FBXL12 328.0
AGL 316.0
TNFSF4 299.0
DCTN5 297.0
SOCS5 292.0
CDC27 283.0
PDCD1LG2 273.0
HERC1 265.0
NUP153 254.0
PCBP2 240.0
KSR2 229.0
HCST 202.0
PTPN3 190.0
TREX1 144.0
ICMT 133.0
STING1 94.0
PPP2R1B 89.0
GOLGA7 14.0
TLR9 -36.0
CUL2 -38.0
PGRMC1 -59.0
HLA-B -98.0
IGHV1-69 -113.0
RNF34 -115.0
TRIM3 -118.0
VAMP8 -139.0
POM121 -142.0
LEAP2 -163.0
EEA1 -171.0
CSF1 -182.0
IL6ST -192.0
RELA -204.0
SPTBN2 -220.0
FBXO27 -222.0
ASB14 -229.0
FBXO17 -234.0
EREG -249.0
HVCN1 -250.0
CD200 -269.0
TRIM17 -285.0
CDH1 -307.0
ENPP4 -308.0
FBXL3 -315.0
HLA-DRB1 -334.0
LRRC7 -340.0
MICA -341.0
RNF6 -360.0
RNASE3 -371.0
IP6K2 -386.0
KIF18A -394.0
KIF26A -414.0
IGLV1-44 -417.0
PYGB -418.0
BTN1A1 -435.0
PSMB8 -438.0
KIR3DL2 -440.0
TRIM62 -442.0
KIR2DL1 -459.0
CISH -483.0
CLCF1 -518.0
FRMPD3 -550.0
ASB13 -571.0
DSP -573.0
AIM2 -585.0
PDE12 -609.0
PTPN7 -645.0
ATF2 -657.0
RASAL1 -658.0
S100A1 -688.0
FBXW9 -691.0
HGSNAT -737.0
RSAD2 -739.0
IL17RB -754.0
GSTP1 -759.0
CYFIP2 -775.0
BST2 -782.0
NME2 -791.0
UBE2D2 -801.0
LAIR2 -805.0
PML -815.0
PRDX4 -834.0
IGKV2D-28 -844.0
IL3RA -895.0
IFITM1 -937.0
IL15RA -946.0
IFNG -958.0
MYO1C -962.0
DUSP10 -973.0
BTNL9 -993.0
UBE2E3 -1020.0
IGHG1 -1043.0
RAB37 -1057.0
MLST8 -1064.0
LYZ -1067.0
IGHG2 -1078.0
CD101 -1089.0
IL10RA -1108.0
UBE2O -1117.0
IGHV3-30 -1129.0
RANBP2 -1141.0
FRS2 -1144.0
LNPEP -1165.0
KLRC2 -1182.0
EPGN -1241.0
CALM1 -1245.0
CCR5 -1251.0
UBE2V1 -1252.0
MAPK12 -1261.0
KPNA1 -1312.0
FBXW7 -1315.0
TNF -1341.0
S100B -1351.0
GFRA2 -1359.0
WASF3 -1364.0
DUSP5 -1402.0
CNTF -1403.0
IGLV1-40 -1411.0
CCNF -1413.0
CPN2 -1422.0
NLRC5 -1423.0
AIP -1433.0
FBXO22 -1440.0
A1BG -1468.0
RNF25 -1470.0
IGKV2-28 -1472.0
IGKV3D-20 -1473.0
TIFA -1479.0
PSPN -1490.0
USP18 -1497.0
MX1 -1518.0
TRIM22 -1548.0
RNF4 -1555.0
KIF15 -1564.0
CD86 -1606.0
CPNE1 -1632.0
TMEM179B -1671.0
TUBB -1675.0
PTPN20 -1692.0
IGLV1-47 -1695.0
HECTD2 -1702.0
TCN1 -1708.0
POM121C -1710.0
PIK3C3 -1718.0
CDC26 -1744.0
KBTBD8 -1765.0
IGKV2-30 -1785.0
HSP90B1 -1788.0
ANAPC10 -1816.0
FN1 -1829.0
IGLV3-27 -1836.0
TNFRSF13C -1841.0
UBE3A -1850.0
MUC12 -1866.0
BAIAP2 -1877.0
AP1S3 -1882.0
CHIT1 -1890.0
SKP2 -1895.0
FGF23 -1952.0
PPBP -1960.0
KPNA3 -1964.0
KLRD1 -1984.0
PAQR3 -2011.0
POLR3K -2014.0
RNF19A -2015.0
SQSTM1 -2046.0
ASB3 -2060.0
IGKV3-20 -2065.0
UBE2N -2071.0
IL18BP -2072.0
GRAP2 -2088.0
PIK3R4 -2097.0
LTN1 -2108.0
IL16 -2114.0
DUSP4 -2116.0
TXNDC5 -2141.0
LAG3 -2169.0
IL4 -2190.0
UBE2V2 -2193.0
IGKV1-12 -2196.0
CRLF1 -2210.0
DAPP1 -2214.0
IGHG4 -2238.0
KLHL42 -2261.0
NUP37 -2275.0
TNFAIP3 -2285.0
BLMH -2286.0
ASB16 -2287.0
IGHM -2289.0
RNF213 -2395.0
NUP62 -2410.0
TNFRSF14 -2428.0
RIPK2 -2451.0
DUSP7 -2452.0
ZNRF2 -2457.0
IGHV3-11 -2459.0
PSMD10 -2515.0
FNTA -2524.0
KPNA2 -2535.0
BRK1 -2561.0
IGLV1-36 -2563.0
FBXO10 -2581.0
PPP2R5E -2595.0
KLHL11 -2610.0
COMMD3 -2657.0
POLR3GL -2666.0
JUP -2668.0
STUB1 -2688.0
ANAPC4 -2692.0
HLA-H -2741.0
BTBD1 -2747.0
CCT8 -2751.0
HACE1 -2752.0
PSMA4 -2764.0
POLR3B -2765.0
IGHV2-70 -2783.0
IRAK2 -2799.0
TRIM37 -2821.0
PSMA2 -2823.0
CD70 -2824.0
TRIM56 -2843.0
YES1 -2846.0
IGLV2-23 -2848.0
CUL5 -2872.0
DUSP8 -2914.0
ATP6V1C2 -2926.0
IGLC7 -2940.0
SOS1 -2983.0
UBE2E1 -2985.0
IGHV3-23 -2995.0
UBA7 -3029.0
FBXL8 -3037.0
IGLV3-25 -3048.0
SVIP -3052.0
CD40 -3053.0
DUSP6 -3055.0
IGHV2-5 -3063.0
ITGB1 -3073.0
SEC61G -3152.0
CCL4 -3160.0
SOCS2 -3165.0
IGHV4-39 -3179.0
ARL2 -3181.0
RNF220 -3197.0
SUGT1 -3240.0
IL15 -3244.0
IL1B -3269.0
CXCL8 -3280.0
UFL1 -3281.0
RCE1 -3302.0
ATG5 -3311.0
AAAS -3332.0
SLPI -3392.0
C3 -3394.0
DAB2IP -3400.0
RAB44 -3423.0
NUP85 -3427.0
KLRC1 -3443.0
PPP5C -3445.0
MRC2 -3464.0
KIR2DS4 -3474.0
PLPP5 -3477.0
TRIM39 -3482.0
FBXW12 -3487.0
UBA52 -3490.0
STAT2 -3493.0
PFKL -3512.0
NFKB2 -3527.0
HERC2 -3535.0
MASP2 -3571.0
MUCL1 -3608.0
PSMB1 -3610.0
C8G -3626.0
CD81 -3627.0
CD1A -3638.0
NOD1 -3652.0
NRG4 -3673.0
ITPR1 -3676.0
NCKIPSD -3692.0
IGLV4-69 -3702.0
TPR -3744.0
IFIT1 -3747.0
TRIM4 -3753.0
CTSV -3775.0
DHX9 -3778.0
IGKV1-5 -3791.0
CCND1 -3813.0
ANAPC2 -3830.0
KIFAP3 -3831.0
IGHV4-59 -3832.0
CLEC10A -3847.0
IGLC1 -3870.0
DHX58 -3871.0
FGF22 -3881.0
ATP6V1E2 -3894.0
NUP210 -3949.0
IGKC -3956.0
CD226 -3960.0
CREB1 -3977.0
EGR1 -4009.0
HSP90AA1 -4016.0
IL31RA -4022.0
TAP2 -4042.0
NUP42 -4045.0
PSMB10 -4050.0
PRKDC -4064.0
RNF115 -4077.0
CDC16 -4089.0
ABHD17A -4101.0
KLHL13 -4118.0
IGHV3-13 -4159.0
S1PR1 -4161.0
RAB9B -4177.0
DHX36 -4199.0
BTRC -4212.0
FBXW8 -4215.0
ABHD17B -4235.0
TCP1 -4240.0
KLC4 -4248.0
BLK -4300.0
IGHG3 -4311.0
PTPRB -4321.0
IL17RC -4347.0
ILF2 -4378.0
GNLY -4390.0
SHC2 -4426.0
C4BPB -4446.0
HLA-DQB1 -4459.0
POLR3C -4461.0
LTF -4464.0
CNKSR2 -4467.0
IGLV8-61 -4469.0
PILRB -4472.0
BTLA -4498.0
KLHL20 -4513.0
IGHV3-7 -4523.0
FGFR4 -4539.0
IFIT3 -4542.0
PSMC5 -4553.0
CD19 -4586.0
OAS3 -4589.0
CD209 -4595.0
CCL5 -4627.0
MAPK11 -4641.0
IGLC2 -4647.0
MIB2 -4725.0
TRAV8-4 -4769.0
ATP6V1G1 -4775.0
EPX -4781.0
ASB2 -4806.0
CASP8 -4824.0
NLRP1 -4847.0
OAS2 -4882.0
FBXL14 -4884.0
MYLIP -4888.0
DYNLL2 -4904.0
POLR2K -4907.0
SIGLEC8 -4925.0
DET1 -4978.0
ASB9 -5007.0
TNFSF15 -5017.0
SIKE1 -5045.0
IGHV3-53 -5054.0
TXNIP -5058.0
ISG15 -5074.0
HRNR -5086.0
IGKV1-33 -5088.0
NCAM1 -5143.0
IGLV2-8 -5148.0
IL12RB1 -5165.0
PPP2R5C -5198.0
FYN -5211.0
NCR3 -5222.0
PA2G4 -5255.0
SLAMF7 -5257.0
PEA15 -5261.0
RICTOR -5264.0
KRT1 -5265.0
HRAS -5273.0
BTBD6 -5304.0
DSN1 -5307.0
XAF1 -5315.0
SEC61A2 -5333.0
NUP133 -5346.0
IGHV1-2 -5353.0
KLRG1 -5396.0
BPI -5410.0
NFKBIE -5439.0
ANAPC13 -5444.0
ANGPT1 -5449.0
KLC2 -5453.0
MAPK9 -5454.0
PTGES2 -5466.0
UBE2E2 -5475.0
FBXO2 -5482.0
SH2B1 -5489.0
PRLR -5500.0
TRIM69 -5508.0
HLA-F -5511.0
PDCD1 -5516.0
RBBP6 -5525.0
MUC4 -5589.0
ALDOC -5613.0
CD8A -5617.0
IGLV7-46 -5638.0
LRR1 -5690.0
IGHD -5698.0
IGLV1-51 -5706.0
IFNLR1 -5734.0
HLA-DOB -5756.0
CHI3L1 -5761.0
ORAI1 -5790.0
BRWD1 -5820.0
PI3 -5828.0
FGFR2 -5834.0
SMURF2 -5858.0
ELK1 -5884.0
THOP1 -5895.0
IL7 -5901.0
PAK3 -5908.0
ATG12 -5923.0
DLG1 -5924.0
IRF1 -5925.0
ACTR1B -5952.0
ZBP1 -5983.0
HLA-A -5985.0
CD180 -6005.0
DPP7 -6012.0
FGL2 -6015.0
MEF2C -6025.0
IGLV3-12 -6030.0
IRS1 -6033.0
PTPN13 -6043.0
RASGRP2 -6127.0
ITPR3 -6139.0
ERBB2 -6142.0
FBXL22 -6147.0
NFATC1 -6177.0
ORMDL3 -6182.0
NPDC1 -6187.0
POLR2H -6200.0
EDA2R -6203.0
RAG1 -6228.0
ICOSLG -6229.0
FGF2 -6231.0
IFIT5 -6232.0
NKIRAS1 -6234.0
AP1M2 -6253.0
JAK1 -6261.0
IGHV3-48 -6262.0
TLR7 -6272.0
SLC27A2 -6278.0
EEF2 -6279.0
IGKV3-15 -6284.0
BLNK -6294.0
SKP1 -6297.0
PHB -6317.0
AAMP -6320.0
RASAL3 -6333.0
IGLV6-57 -6338.0
PPIE -6341.0
IGLV3-1 -6354.0
HLA-DQA1 -6389.0
RALA -6392.0
SRC -6396.0
IGHV4-34 -6414.0
PSMA3 -6433.0
DEFA3 -6439.0
GBP2 -6451.0
NUP93 -6458.0
SLC2A5 -6479.0
TRAIP -6492.0
PPIA -6498.0
CR2 -6534.0
TMC6 -6551.0
KLRK1 -6555.0
FBXO44 -6558.0
TAP1 -6582.0
ATP6V0A2 -6587.0
MTAP -6590.0
UBA5 -6606.0
IGLV5-45 -6611.0
TRIM35 -6612.0
SHC3 -6615.0
ERAP1 -6626.0
NFATC3 -6650.0
TNFSF11 -6653.0
IGHE -6665.0
MRE11 -6668.0
HMGB1 -6699.0
CFH -6709.0
IRF3 -6721.0
RASGRP3 -6748.0
HERC5 -6774.0
PRR5 -6787.0
SIGIRR -6838.0
KIF2A -6844.0
TRIM68 -6853.0
CD4 -6881.0
FBXO21 -6888.0
IGKV1-16 -6894.0
IL20RB -6905.0
ABCA13 -6934.0
B2M -6943.0
CRTAM -6946.0
UBE2Z -6951.0
KIF5A -6961.0
BCL2 -6977.0
MUC20 -6993.0
MS4A3 -7001.0
RNF216 -7008.0
ZEB1 -7028.0
CAND1 -7058.0
NUP155 -7061.0
TLR10 -7067.0
LILRA4 -7084.0
BTN3A1 -7089.0
CD79A -7093.0
FBXW4 -7094.0
MIF -7102.0
TRIM45 -7110.0
NUP54 -7131.0
ISG20 -7136.0
POLR3G -7146.0
GZMM -7149.0
PLA2G6 -7168.0
NOS3 -7169.0
FASLG -7230.0
NRG1 -7233.0
CD22 -7244.0
IFIT2 -7247.0
SNRPA1 -7256.0
IGLV2-14 -7284.0
SCAMP1 -7313.0
IGKV4-1 -7319.0
PSME2 -7327.0
FGF7 -7330.0
CIITA -7357.0
IGLV3-19 -7364.0
NCR1 -7382.0
NCR3LG1 -7401.0
TLR3 -7411.0
SOD1 -7420.0
RALGDS -7432.0
DUSP2 -7443.0
TRAF2 -7465.0
IL21R -7467.0
PSMA5 -7476.0
ANAPC5 -7485.0
COLEC12 -7487.0
IFIH1 -7494.0
DDX58 -7512.0
NUP205 -7516.0
RASA4 -7530.0
CD8B -7536.0
TRAF3 -7539.0
CLEC2B -7542.0
CEACAM8 -7546.0
APRT -7580.0
MEX3C -7586.0
RNF138 -7589.0
HLA-DMA -7607.0
TBC1D10C -7608.0
SERPING1 -7610.0
OLR1 -7621.0
ITGA4 -7628.0
AGA -7674.0
DEFA1 -7680.0
IL2RA -7681.0
IL12A -7688.0
LGMN -7705.0
IL2RG -7711.0
TNFRSF17 -7718.0
DEFA4 -7723.0
UBE2L6 -7739.0
POLR3F -7749.0
PSME1 -7778.0
IRF6 -7787.0
SYNGAP1 -7809.0
TNFRSF13B -7833.0
KLHL5 -7844.0
SMAD3 -7868.0
IL17RE -7873.0
CD274 -7895.0
ARIH2 -7941.0
NUP188 -7953.0
SLAMF6 -7954.0
TMEM63A -7978.0
CD34 -7979.0
UBE2D4 -7998.0
IGLV2-18 -8002.0
IRF4 -8063.0
CD79B -8065.0
BTN2A2 -8089.0
CD3G -8111.0
UBE3D -8120.0
SPTBN1 -8138.0
HERC6 -8142.0
HLA-DOA -8145.0
XRCC6 -8146.0
ITGB7 -8150.0
CEP290 -8156.0
ABI2 -8174.0
RNF126 -8201.0
DUSP16 -8213.0
CD80 -8215.0
HLA-DPA1 -8217.0
CNKSR1 -8238.0
DLG3 -8241.0
IL5RA -8245.0
TRIM32 -8252.0
MPO -8263.0
KLHL22 -8266.0
CEACAM6 -8277.0
SARM1 -8283.0
NUP107 -8285.0
CD3D -8297.0
TRBV7-9 -8303.0
CCL3 -8305.0
IGHV3-33 -8309.0
EDA -8314.0
CD74 -8337.0
MS4A2 -8347.0
ATAD3B -8354.0
NUP160 -8357.0
IGLV3-21 -8363.0
NUP43 -8368.0
ELANE -8371.0
PTPN4 -8389.0
HLA-DPB1 -8397.0
CBLB -8415.0
CAMP -8417.0
IL12RB2 -8465.0
FGF9 -8476.0
PSMB9 -8503.0
NFATC2 -8513.0
KCTD7 -8523.0
NLRC3 -8550.0
LNX1 -8590.0
POLR3E -8594.0
GBP3 -8605.0
TRPC1 -8607.0
MAP3K14 -8618.0
CTSO -8626.0
VAMP2 -8673.0
CDC23 -8677.0
RHOF -8679.0
CTLA4 -8684.0
CARD11 -8722.0
TPP2 -8735.0
CD247 -8741.0
HLA-DMB -8751.0
ZAP70 -8755.0
EDARADD -8773.0
HLA-DQA2 -8774.0
HMOX2 -8794.0
PRKG2 -8799.0
AKT3 -8810.0
STAT4 -8814.0
KLRF1 -8819.0
PIK3R1 -8831.0
MAPK8 -8929.0
TRIM46 -8945.0
CD160 -8951.0
NCK1 -8975.0
IL32 -8976.0
AP1S2 -8979.0
BTN3A3 -8997.0
POLR3D -9004.0
HLA-DRA -9006.0
PJA1 -9012.0
HNRNPDL -9013.0
KPNA5 -9017.0
IL11RA -9023.0
PIANP -9041.0
HSPA8 -9129.0
POLR1C -9141.0
ATP6V1G2 -9143.0
GBP1 -9145.0
NIT2 -9152.0
PDE3B -9157.0
CD47 -9164.0
TP53 -9170.0
HSP90AB1 -9172.0
NEFL -9178.0
RORA -9193.0
KLHL25 -9211.0
ATP8A1 -9218.0
RPLP0 -9227.0
CLEC2D -9237.0
TRAV19 -9248.0
CD3E -9249.0
TRAV29DV5 -9278.0
GLMN -9292.0
TRBC1 -9303.0
RASA3 -9306.0
PRTN3 -9350.0
MYC -9357.0
EDAR -9371.0
TRIM2 -9376.0
AZU1 -9380.0
RPS6KA5 -9386.0
RASGRP1 -9394.0
TNFRSF18 -9397.0
PLCG1 -9412.0
CUL1 -9420.0
PRKCQ -9424.0
KIF3A -9438.0
STAT1 -9448.0
IGKV3-11 -9449.0
ATP6V0E2 -9456.0
SPTAN1 -9461.0
FCER1A -9468.0
LAT -9470.0
ALOX15 -9484.0
TNFRSF4 -9489.0
CTSG -9503.0
UBE2Q2 -9504.0
LTA -9512.0
GBP5 -9519.0
IL24 -9522.0
UBE2G2 -9540.0
LCK -9556.0
EVL -9560.0
PDGFB -9562.0
RASGRF2 -9563.0
SEH1L -9574.0
ICAM2 -9588.0
EIF4A2 -9593.0
LMO7 -9595.0
SIGLEC6 -9617.0
TXK -9627.0
DSC1 -9630.0
IL2RB -9646.0
HLA-DQB2 -9656.0
NUP88 -9668.0
ITK -9674.0
POLR3H -9693.0
FBXO32 -9702.0
TRAC -9703.0
RPS27A -9723.0
FBXO31 -9725.0
NUP35 -9726.0
FOXO1 -9731.0
GBP4 -9739.0
HSPA9 -9747.0
EEF1A1 -9751.0
TNFSF8 -9764.0
LTB -9791.0
BTN3A2 -9794.0
RNF125 -9797.0
CTSF -9824.0
FBXO4 -9825.0
ANAPC1 -9829.0
PEBP1 -9843.0
KIF22 -9850.0
PRKACB -9863.0
CAMK2D -9907.0
DZIP3 -9919.0
CD200R1 -9922.0
SH2D1B -9928.0
CD27 -9935.0
PDCD4 -9947.0
ICOS -9952.0
CD40LG -9953.0
CYLD -9961.0
TRBV12-3 -9971.0
SH2D1A -9973.0
WWP1 -9985.0
IL9R -9991.0
IL23A -9994.0
CCT2 -10024.0
KLHL3 -10032.0
BIRC3 -10039.0
TRAT1 -10049.0
MALT1 -10050.0
CD96 -10058.0
CXCL10 -10060.0
GATA3 -10071.0
ABCE1 -10073.0
NDC1 -10077.0
FLT3LG -10078.0
THEM4 -10102.0
KLRB1 -10104.0
FBXL16 -10105.0
CCR6 -10108.0
PLD4 -10109.0
KIT -10114.0
TNFRSF25 -10123.0
IMPDH2 -10126.0
KIF5C -10128.0
CD1C -10141.0
IL7R -10153.0
CD28 -10159.0
RORC -10162.0


Influenza Infection

Influenza Infection
525
set Influenza Infection
setSize 154
pANOVA 4.36e-27
s.dist -0.503
p.adjustANOVA 2.28e-25



Top enriched genes

Top 20 genes
GeneID Gene Rank
IPO5 -10129
NDC1 -10077
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
NUP35 -9726
RPS27A -9723
RPS6 -9699
RPL14 -9698
NUP88 -9668
RPS25 -9664
RPL22 -9659
RPS2 -9591
SEH1L -9574
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IPO5 -10129
NDC1 -10077
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
NUP35 -9726
RPS27A -9723
RPS6 -9699
RPL14 -9698
NUP88 -9668
RPS25 -9664
RPL22 -9659
RPS2 -9591
SEH1L -9574
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
RPL27A -9048
RPS5 -9042
RPL10 -9031
KPNA5 -9017
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
RPS16 -8579
RPS14 -8541
RPS10 -8494
RAN -8475
PARP1 -8391
RPL23 -8373
NUP43 -8368
NUP160 -8357
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
NUP107 -8285
RPS17 -8281
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
RPS28 -8083
RPS11 -7975
RPL38 -7968
NUP188 -7953
RPL37 -7861
RPL27 -7810
RPS19 -7806
RPL13 -7671
RPL41 -7561
NUP205 -7516
RPL36 -7493
NUP54 -7131
NUP155 -7061
POLR2D -6856
RPL37A -6833
RPL9 -6821
RPS24 -6818
RPS15 -6703
RPL36AL -6646
RPSA -6629
NUP93 -6458
POLR2H -6200
RPL8 -6101
RPLP1 -6018
SLC25A6 -5588
NUP133 -5346
ISG15 -5074
POLR2K -4907
NUP42 -4045
CPSF4 -4025
HSP90AA1 -4016
NUP210 -3949
POLR2I -3929
RPL28 -3873
TPR -3744
FAU -3618
UBA52 -3490
NUP85 -3427
POLR2B -3384
AAAS -3332
XPO1 -3214
GRSF1 -2923
KPNA2 -2535
NUP62 -2410
NUP37 -2275
KPNA3 -1964
PABPN1 -1789
POM121C -1710
RPL39L -1661
KPNA1 -1312
RPS26 -1154
RANBP2 -1141
RPS27L -496
POLR2C -494
POM121 -142
NUP153 254
RPS4Y1 331
RPS9 1841
POLR2L 2016
NUP50 2638
CANX 3332
POLR2G 4175
POLR2F 4256
RAE1 5007
POLR2E 5109
RPL3L 5150
TGFB1 5504
EIF2AK2 5594
POLR2J 5598
KPNB1 5604
KPNA4 5698
NUP98 5874
RPL26L1 6001
GTF2F2 6257
GTF2F1 6738
CLTA 7164
SEC13 7506
CALR 7713
POLR2A 7852
HSPA1A 9341
NUP58 9577
DNAJC3 9831
NUP214 10131
CLTC 10304


SRP-dependent cotranslational protein targeting to membrane

SRP-dependent cotranslational protein targeting to membrane
1038
set SRP-dependent cotranslational protein targeting to membrane
setSize 111
pANOVA 1.23e-26
s.dist -0.586
p.adjustANOVA 6.19e-25



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
RPS16 -8579
RPS14 -8541
RPS10 -8494
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
RPS28 -8083
RPS11 -7975
RPL38 -7968
RPL37 -7861
RPL27 -7810
RPS19 -7806
RPL13 -7671
RPL41 -7561
SRPRB -7520
RPL36 -7493
RPL37A -6833
RPL9 -6821
RPS24 -6818
RPS15 -6703
RPL36AL -6646
RPSA -6629
TRAM1 -6480
RPL8 -6101
SEC11C -6046
RPLP1 -6018
SEC61A2 -5333
RPL28 -3873
FAU -3618
SRP72 -3562
UBA52 -3490
SRP9 -3414
SEC61G -3152
SSR2 -2917
SPCS1 -1700
RPL39L -1661
RPS26 -1154
SPCS2 -977
SRP19 -625
RPS27L -496
RPS4Y1 331
SRP68 787
SSR1 1143
SSR4 1294
RPS9 1841
SPCS3 1967
SSR3 2510
SEC61B 4322
SRP14 5022
RPL3L 5150
RPL26L1 6001
SEC11A 6634
RPN1 7151
SEC61A1 7486
SRP54 7912
SRPRA 8301
DDOST 8464
RPN2 8874


Vesicle-mediated transport

Vesicle-mediated transport
1310
set Vesicle-mediated transport
setSize 648
pANOVA 2e-20
s.dist 0.213
p.adjustANOVA 9.72e-19



Top enriched genes

Top 20 genes
GeneID Gene Rank
STAB1 11455
F5 11434
GNS 11410
SERPINA1 11407
MARCO 11380
PLIN3 11351
AP2A1 11340
CD163 11316
HP 11312
CUX1 11300
AMPH 11248
SNX18 11203
RIN1 11169
ULK1 11151
COPG1 11142
SBF2 11135
TBC1D14 11112
VAMP7 11110
DENND3 11024
TGFA 10983

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
STAB1 11455
F5 11434
GNS 11410
SERPINA1 11407
MARCO 11380
PLIN3 11351
AP2A1 11340
CD163 11316
HP 11312
CUX1 11300
AMPH 11248
SNX18 11203
RIN1 11169
ULK1 11151
COPG1 11142
SBF2 11135
TBC1D14 11112
VAMP7 11110
DENND3 11024
TGFA 10983
ARPC1A 10981
RAB10 10956
CD36 10947
CD55 10914
GALNT2 10885
AP1B1 10872
MAN1A1 10830
SEC24D 10803
BLOC1S1 10801
TBC1D2 10799
LRP1 10795
RIN2 10772
ITSN1 10737
GRB2 10733
CPD 10712
EPN1 10697
ARRB2 10688
DCTN4 10682
RAB31 10661
DAB2 10645
LDLR 10634
RAB32 10626
RAC1 10624
RAB13 10611
ARF1 10610
RALGAPA2 10588
GJD3 10584
SYNJ1 10567
COPA 10521
HIP1 10519
AGFG1 10514
IGF2R 10494
SORT1 10465
KIF1B 10454
YWHAG 10453
CYTH4 10450
MON1B 10423
TBC1D10B 10419
DCTN2 10412
VPS37C 10402
DNM2 10373
PREB 10364
UBAP1 10354
ACTR1A 10310
TGOLN2 10307
CLTC 10304
PACSIN2 10295
MAN2A2 10274
RAB39A 10255
EXOC6 10253
PICALM 10243
STX10 10228
AP1S1 10225
AP2A2 10223
CHMP2A 10205
TBC1D1 10161
CHMP4B 10154
RAB7A 10115
ARPC5 10102
FTL 10101
REPS2 10081
RAB1B 10055
YWHAH 10050
CHMP5 10034
COG7 9987
RAB1A 9971
RAB6A 9958
CTSZ 9943
IGLV7-43 9914
CBL 9903
NSF 9870
RAB5C 9864
DENND5A 9804
PLA2G4A 9803
TRAPPC12 9770
BICD2 9707
GRK3 9662
SCARB2 9643
GORASP1 9633
SH3GL1 9632
RAB27A 9628
KDELR1 9613
AP1M1 9595
ARPC4 9592
IGKV1-39 9590
EXOC7 9580
CAPZB 9575
DCTN1 9558
MYO5A 9548
CAPZA1 9530
KIF1C 9483
LMAN2 9480
ARF3 9465
SEC16A 9460
VPS25 9447
SEC24A 9414
GOLGA2 9412
GRK2 9386
KIF3C 9374
ARF4 9348
OCRL 9323
HGS 9317
VAMP3 9311
VTI1A 9303
CTSC 9276
MYH9 9224
GAK 9209
CLTCL1 9201
TOR1B 9184
PPP6R1 9179
SNAP29 9157
GOLIM4 9092
TRAPPC1 9087
GOLGA1 9075
ARPC2 9016
SEC24C 8993
YWHAE 8971
DENND4B 8934
SEC16B 8899
COPB2 8898
ACTR2 8895
KLC1 8888
ACTR3 8873
RAB3IL1 8870
HPS1 8846
GAPVD1 8844
TOR1A 8807
AP2M1 8799
VPS37A 8762
MVB12B 8734
ARPC3 8726
COPS7A 8712
COPG2 8709
ALB 8630
VPS37B 8615
CHMP3 8606
STX5 8547
GGA3 8491
CSNK1D 8475
EPS15L1 8461
KIF13B 8431
NAA38 8425
COG4 8402
RAB36 8383
ARF5 8313
SURF4 8306
DYNC1LI1 8276
RAB5B 8258
EXOC1 8238
COPE 8230
CAPZA2 8225
MIA2 8200
KIF5B 8197
TBC1D13 8195
SYT2 8154
TFG 8124
RABGEF1 8058
AP2S1 8045
TMED9 8028
F8 8026
MAP1LC3B 8019
COPB1 7997
COL7A1 7971
CLTB 7968
AGPAT3 7932
KIAA0319 7910
TSG101 7901
PAFAH1B1 7857
AP3B1 7854
SNAPIN 7826
CHMP6 7813
PRKAG1 7805
GDI1 7789
PIP5K1C 7742
RAB8B 7739
STX6 7734
CALR 7713
TRAPPC8 7708
SPTB 7702
GBF1 7683
RIC1 7660
DENND2C 7658
DYNC1LI2 7644
YKT6 7621
NEDD8 7558
DCTN6 7540
SNAP23 7530
GABARAPL2 7529
RAB35 7522
GOLGA5 7519
NAPG 7516
TRAPPC11 7513
SEC13 7506
FNBP1L 7449
ALS2 7445
STAM2 7431
ARFGAP3 7424
AP4M1 7364
RGP1 7355
SEC24B 7352
PUM1 7329
EXOC3 7328
AP1G1 7318
FCHO2 7311
DENND1A 7260
STXBP3 7210
CLTA 7164
RAB5A 7154
PRKAB1 7148
SEC23A 7129
GGA1 7102
GABARAP 7075
TBC1D7 7042
RAB18 7038
STX4 7026
MVB12A 6984
ARCN1 6965
GDI2 6949
SAR1B 6893
FTH1 6883
RAB43 6846
SYT11 6842
YIPF6 6839
KIF9 6805
IGLV10-54 6741
DYNC1I2 6705
HBB 6697
NAPA 6660
DCTN3 6625
RAB11A 6617
RAB3GAP2 6599
ITSN2 6557
TRAPPC9 6548
AKT1 6498
GALNT1 6495
SNX2 6471
EXOC4 6466
KLC3 6451
RABEPK 6419
STX18 6405
KDELR2 6387
VPS53 6373
SCFD1 6297
RAB3A 6284
SEC22B 6272
APP 6245
HBA1 6237
ANKRD27 6228
RAB21 6196
TMEM115 6183
UBC 6135
RAB7B 6060
EPS15 6059
AP3S1 6030
DNM1 5998
PAFAH1B2 5996
GOSR2 5986
CENPE 5930
NECAP1 5923
TBC1D8B 5919
RACGAP1 5897
ACTR10 5886
SH3KBP1 5885
EXOC8 5853
CCZ1 5832
KIF18B 5806
RABGAP1 5785
DNASE2 5689
ANK1 5655
TBC1D16 5645
TBC1D24 5578
CLINT1 5548
UBQLN2 5531
RAB8A 5522
AKT2 5502
RAB14 5469
SYT1 5438
CCZ1B 5430
SNF8 5420
KIF3B 5396
UBQLN1 5365
TMED2 5345
EGF 5267
YWHAZ 5202
RAB3GAP1 5167
MCFD2 5134
KIF27 5112
RAB33B 5028
AP4E1 5016
STX16 4979
KIF21B 4976
GJC1 4969
VPS4B 4920
FNBP1 4869
VPS54 4853
TFRC 4842
SPTBN5 4732
YWHAB 4721
IGKV5-2 4704
KIF4A 4526
TRAPPC3 4443
IGLV2-11 4439
SEC31A 4346
ARFGAP2 4331
TSC2 4311
LRP2 4295
KIF23 4278
CD59 4252
CNIH2 4186
SPTA1 4063
SCGB3A2 4042
HYOU1 4037
TMED7 3978
GCC1 3975
RAB11B 3969
ARRB1 3956
TBC1D20 3947
VTA1 3940
IGLC3 3928
KIF20A 3824
IGKV1D-39 3734
PPP6R3 3723
COPS5 3579
GJB6 3533
DNM3 3523
STAB2 3499
FZD4 3498
CHMP4A 3465
AVPR2 3452
TMED3 3420
WASL 3297
VPS52 3262
TRAPPC5 3257
NAPB 3180
MADD 3143
CFTR 3091
CHMP2B 3087
COL4A2 3049
CYTH2 3016
ARF6 3007
ARFGAP1 2978
AP2B1 2910
DYNC1I1 2879
EPN2 2846
TPD52L1 2819
RHOQ 2797
COL1A2 2707
DNAJC6 2611
TRAPPC10 2565
APOE 2448
USO1 2424
AREG 2386
DENND1C 2358
COG5 2352
KIF6 2255
TBC1D25 2205
PPP6C 2138
RALGAPB 2083
HBEGF 2064
IGKV1-17 2037
KIF2C 2011
ACBD3 1983
SNX9 1918
SFN 1840
DYNC1H1 1705
MSR1 1663
LMAN2L 1586
DYNLL1 1530
RAB41 1488
TMF1 1460
NBAS 1441
TSC1 1403
SNX5 1377
DENND6A 1376
TRAPPC6B 1327
COPS3 1310
TF 1246
CHM 1115
POLG 1085
UBB 1026
KIF19 1011
STON1 956
COPS2 934
STAM 907
KDELR3 869
RAB27B 774
SEC23IP 737
MON1A 707
DENND6B 706
RAB33A 620
IGHV1-46 618
VAMP4 607
TBC1D3 561
EXOC5 550
BLOC1S3 547
KIF11 545
CTTN 514
COPZ1 412
COG8 406
USP6NL 325
DCTN5 297
KIFC1 288
SCARB1 284
VPS4A 169
IGHV1-69 -113
VAMP8 -139
REPS1 -150
SPTBN2 -220
EREG -249
TJP1 -300
VPS45 -382
KIF18A -394
KIF26A -414
IGLV1-44 -417
TRAPPC13 -481
RAB3IP -569
AP4B1 -603
ZW10 -627
STON2 -635
GJC2 -694
VPS28 -758
IGKV2D-28 -844
MYO1C -962
SPARC -1002
IGHV3-30 -1129
FCHO1 -1148
LNPEP -1165
EPGN -1241
COPS6 -1242
CALM1 -1245
SSC5D -1267
GGA2 -1297
IGLV1-40 -1411
RINL -1455
IGKV2-28 -1472
IGKV3D-20 -1473
PIK3C2A -1501
KIF15 -1564
BET1L -1574
HPX -1586
IGHA2 -1596
RAB4A -1669
IGLV1-47 -1695
RAB9A -1713
IGKV2-30 -1785
HSP90B1 -1788
IGLV3-27 -1836
RAB6B -1849
TRAPPC2L -1855
AP1S3 -1882
PRKAG2 -1916
SYS1 -2040
IGKV3-20 -2065
RAB12 -2139
TXNDC5 -2141
BLOC1S6 -2146
COG3 -2175
IGKV1-12 -2196
BICD1 -2303
GPS1 -2376
IGHV3-11 -2459
TRAPPC4 -2490
DENND4A -2494
IGLV1-36 -2563
CNIH1 -2698
TRIP11 -2705
COPS4 -2731
ARL1 -2770
IGHV2-70 -2783
IGLV2-23 -2848
IGLC7 -2940
IGHV3-23 -2995
IGLV3-25 -3048
IGHV2-5 -3063
GOSR1 -3080
ADRB2 -3128
KIFC2 -3136
SEC22C -3143
DENND1B -3163
SBF1 -3176
IGHV4-39 -3179
TBC1D15 -3245
RAB38 -3316
APOL1 -3354
AAK1 -3358
DTNBP1 -3372
AP1G2 -3387
C2CD5 -3422
UBA52 -3490
MYO6 -3522
GOLGA4 -3561
RHOBTB3 -3616
DENND2A -3622
MIA3 -3686
IGLV4-69 -3702
COPS7B -3712
NECAP2 -3755
DENND4C -3756
IGHA1 -3787
TBC1D10A -3790
IGKV1-5 -3791
KIFAP3 -3831
IGHV4-59 -3832
IGLC1 -3870
IGKC -3956
GOLGB1 -4004
MAN2A1 -4015
HSP90AA1 -4016
SCARF1 -4027
ARFIP2 -4029
PAFAH1B3 -4044
MAN1A2 -4146
IGHV3-13 -4159
RAB9B -4177
AP4S1 -4191
KLC4 -4248
CYTH3 -4278
TBC1D17 -4327
KIF28P -4361
TMED10 -4413
CNIH3 -4435
IGLV8-61 -4469
VPS36 -4497
IGHV3-7 -4523
ARFRP1 -4525
EXOC2 -4563
RABEP1 -4568
KIF16B -4619
YWHAQ -4624
IGLC2 -4647
SYTL1 -4650
M6PR -4860
DYNLL2 -4904
CHML -4951
IGHV3-53 -5054
IGKV1-33 -5088
USE1 -5115
IGLV2-8 -5148
IGHV1-2 -5353
KLC2 -5453
PRKAB2 -5520
COG2 -5554
DVL2 -5637
IGLV7-46 -5638
ANKRD28 -5681
IGLV1-51 -5706
COPZ2 -5974
DENND5B -6013
IGLV3-12 -6030
TRIP10 -6094
ASPSCR1 -6098
SH3D19 -6131
BLOC1S4 -6160
BNIP1 -6184
SLC2A8 -6202
AP1M2 -6253
IGHV3-48 -6262
IGKV3-15 -6284
IGLV6-57 -6338
BET1 -6342
IGLV3-1 -6354
RALA -6392
SRC -6396
IGHV4-34 -6414
GCC2 -6501
IGLV5-45 -6611
HPS4 -6635
COG6 -6645
JCHAIN -6676
NAA35 -6750
KIF21A -6834
KIF2A -6844
CD4 -6881
IGKV1-16 -6894
KIF5A -6961
TRAPPC2 -7043
COG1 -7045
PLA2G6 -7168
KIF20B -7260
IGLV2-14 -7284
IGKV4-1 -7319
KIF26B -7360
IGLV3-19 -7364
COLEC12 -7487
NAA30 -7523
TBC1D10C -7608
ANK3 -7751
HSPH1 -7758
SEC22A -7808
IGLV2-18 -8002
STX17 -8013
CD3G -8111
SPTBN1 -8138
VPS51 -8242
CD3D -8297
IGHV3-33 -8309
IGLV3-21 -8363
RAB39B -8372
OPTN -8400
LMAN1 -8522
HIP1R -8608
RAB30 -8666
VAMP2 -8673
TPD52 -8806
AKT3 -8810
COPS8 -8830
AP1S2 -8979
RINT1 -8985
CYTH1 -9019
CHMP7 -9039
SCOC -9113
HSPA8 -9129
BIN1 -9243
SYNJ2 -9322
DENND2D -9419
KIF3A -9438
IGKV3-11 -9449
SPTAN1 -9461
TRAPPC6A -9543
PACSIN1 -9553
RPS27A -9723
KIF22 -9850
MAN1C1 -9944
LDLRAP1 -10002
ALS2CL -10013
TBC1D4 -10097
KIF5C -10128
IL7R -10153


Signal Transduction

Signal Transduction
1067
set Signal Transduction
setSize 1882
pANOVA 2.53e-19
s.dist 0.125
p.adjustANOVA 1.19e-17



Top enriched genes

Top 20 genes
GeneID Gene Rank
CSF2RA 11457
PLB1 11453
NCSTN 11452
PPARG 11451
H2AJ 11447
ADM 11444
FZD5 11440
GRB10 11433
HRH2 11427
EDNRB 11422
NOTCH3 11420
ARHGEF11 11412
SMAD1 11403
SH2B2 11393
NUMB 11392
P2RY1 11378
GPER1 11368
ACVR1B 11364
PRKACA 11363
GPR27 11347

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CSF2RA 11457.0
PLB1 11453.0
NCSTN 11452.0
PPARG 11451.0
H2AJ 11447.0
ADM 11444.0
FZD5 11440.0
GRB10 11433.0
HRH2 11427.0
EDNRB 11422.0
NOTCH3 11420.0
ARHGEF11 11412.0
SMAD1 11403.0
SH2B2 11393.0
NUMB 11392.0
P2RY1 11378.0
GPER1 11368.0
ACVR1B 11364.0
PRKACA 11363.0
GPR27 11347.0
RASGRP4 11346.0
LAMC1 11344.0
WNT11 11342.0
ATP6AP1 11341.0
AP2A1 11340.0
GMIP 11339.0
MYD88 11331.0
WASF1 11328.0
CTNNA1 11326.0
PLCB3 11314.0
NCKAP1L 11304.0
CTSD 11297.0
C3AR1 11294.0
ATP6V0A1 11283.0
RHOU 11282.0
DLC1 11274.0
ALDH1A2 11272.0
ABR 11251.0
MAPKAPK3 11249.0
ACVRL1 11242.0
EPAS1 11229.0
TLE3 11222.0
FPR1 11221.0
FSTL3 11218.0
NCOR2 11217.0
MAPK1 11193.0
CASP9 11186.0
PTK2B 11185.0
S100A8 11184.0
ADGRE1 11183.0
LTB4R 11176.0
PRKCD 11168.0
MMP2 11162.0
FLT1 11152.0
PHC2 11145.0
TCIRG1 11138.0
SUFU 11132.0
PLEKHG2 11117.0
MAPK14 11115.0
ADCY3 11111.0
OPRL1 11107.0
ARHGAP29 11104.0
RPS6KA1 11103.0
RHOT1 11096.0
KREMEN1 11087.0
ARHGAP26 11079.0
C5AR1 11061.0
ADGRE2 11039.0
RTN4 11038.0
ATP6V0D1 11016.0
ATP6V0C 10995.0
ARHGAP27 10993.0
TNFRSF1A 10988.0
TGFA 10983.0
ARPC1A 10981.0
PROK2 10979.0
FKBP5 10974.0
FES 10973.0
ADAM17 10964.0
OS9 10951.0
FMNL2 10945.0
RNF146 10941.0
MMP9 10920.0
PTPN18 10915.0
CD55 10914.0
GNA15 10907.0
FURIN 10905.0
HDAC4 10884.0
FPR2 10883.0
PIK3AP1 10882.0
RGL3 10853.0
BTK 10849.0
MECOM 10834.0
MYO9B 10832.0
TYK2 10828.0
SOCS3 10826.0
MRTFA 10825.0
NCF4 10813.0
ECE1 10811.0
LYN 10810.0
SMAD6 10809.0
RARA 10808.0
WASF2 10807.0
LRP1 10795.0
NCF2 10793.0
MARK3 10787.0
WWP2 10784.0
PREX1 10783.0
ARPC1B 10781.0
SRGAP2 10779.0
WAS 10777.0
TCF7L2 10773.0
OMG 10769.0
TAS2R40 10762.0
RGL1 10752.0
FRAT2 10745.0
ARAP1 10740.0
ITSN1 10737.0
GRB2 10733.0
GNG5 10721.0
MYO7A 10707.0
USP4 10702.0
EPN1 10697.0
RIT1 10696.0
ARRB2 10688.0
PLXND1 10671.0
C5AR2 10670.0
CFLAR 10655.0
CTBP2 10652.0
MAML3 10651.0
CLIP1 10646.0
CAMKK2 10644.0
RHOG 10635.0
LDLR 10634.0
GPR84 10632.0
CDK5 10628.0
RAC1 10624.0
PTPN1 10623.0
APBB1IP 10622.0
S100A9 10613.0
PLPPR2 10607.0
ACTB 10606.0
RCOR1 10600.0
KSR1 10576.0
BAMBI 10550.0
AGO4 10537.0
FGD4 10532.0
RUNX1 10531.0
GAB2 10528.0
PRKAR1A 10510.0
EIF4G1 10506.0
FGD2 10505.0
SPRED2 10499.0
CCND3 10476.0
FRAT1 10472.0
TJP2 10458.0
CAMKK1 10455.0
YWHAG 10453.0
ARHGAP1 10447.0
PTPN6 10446.0
DVL3 10441.0
KDM4B 10436.0
PSEN1 10429.0
ARHGEF40 10425.0
CYFIP1 10420.0
HGF 10417.0
EPOR 10409.0
SNX3 10408.0
DOK1 10406.0
NDEL1 10403.0
GNB1 10392.0
LPL 10391.0
CRK 10387.0
TLE4 10384.0
MAP3K11 10375.0
DNM2 10373.0
ATP2A2 10359.0
PDE1B 10346.0
PTPRJ 10340.0
DAGLB 10338.0
SHB 10331.0
MKNK1 10325.0
TRIM27 10324.0
KLHL12 10318.0
ARHGAP24 10317.0
CARM1 10313.0
CLTC 10304.0
NOTCH4 10293.0
GNB2 10282.0
RNF41 10276.0
KEL 10275.0
CXCL16 10265.0
GNAI2 10264.0
SYK 10256.0
PLCG2 10244.0
VAV1 10226.0
AP2A2 10223.0
ST3GAL4 10218.0
APOD 10209.0
RAPGEF2 10206.0
LPAR2 10193.0
TLN1 10191.0
ELMO2 10190.0
PTAFR 10188.0
MYL6 10185.0
RBPJ 10176.0
CYBA 10173.0
ARAP3 10157.0
MAP2K1 10148.0
PXN 10135.0
RALB 10104.0
ARPC5 10102.0
P4HB 10093.0
ADAP1 10090.0
PSMD4 10088.0
RGS19 10074.0
RXRA 10073.0
GNG10 10071.0
CDH5 10065.0
IQCE 10057.0
YWHAH 10050.0
ARHGDIB 10049.0
MAML1 10046.0
PAK1 10043.0
IQGAP1 10037.0
MAPK7 10035.0
PIK3R6 10025.0
LRP10 10024.0
PDGFRA 10015.0
SRGAP1 9993.0
ADAM10 9992.0
ATP6V1D 9982.0
GSK3A 9979.0
CDC42EP3 9964.0
LYL1 9959.0
RAB6A 9958.0
TNS3 9957.0
SNAI1 9938.0
REEP4 9928.0
PPP2R5B 9913.0
RGL2 9912.0
CBL 9903.0
ATP6V1C1 9900.0
JAK3 9899.0
MEF2A 9891.0
LAMB1 9873.0
GNAQ 9871.0
STAT6 9852.0
ARHGAP19 9828.0
PPP2R5A 9827.0
DLG4 9813.0
PLA2G4A 9803.0
FOXO3 9800.0
ARHGEF2 9798.0
CFL1 9794.0
EP300 9789.0
TEC 9787.0
ATP6V0B 9782.0
MAPK3 9750.0
SOS2 9744.0
STAT3 9739.0
CCRL2 9733.0
PLTP 9710.0
STK3 9709.0
CNGB1 9705.0
ARHGAP9 9702.0
SP1 9699.0
H2BC21 9690.0
LIMK2 9689.0
APOA2 9687.0
RAF1 9686.0
ACTG1 9678.0
NEDD4 9677.0
CTNNB1 9670.0
BAG4 9667.0
GRK3 9662.0
CYBB 9660.0
LRP8 9649.0
MAPK13 9645.0
DIAPH2 9644.0
VAPA 9635.0
SH3GL1 9632.0
GRIN2D 9631.0
FLT3 9618.0
MRAS 9617.0
RLBP1 9608.0
CCR2 9605.0
ARPC4 9592.0
PTEN 9545.0
SHC1 9541.0
ATP6V1A 9534.0
NTSR1 9525.0
NR1H2 9521.0
KL 9509.0
ZDHHC9 9508.0
CCR1 9507.0
NOTCH1 9499.0
OR2C3 9494.0
MOB1A 9475.0
APH1B 9474.0
ID2 9463.0
IKBKG 9441.0
ATP6V1B2 9436.0
IRS2 9427.0
CSF2RB 9423.0
RHOA 9401.0
CSK 9400.0
INSR 9393.0
GRK2 9386.0
SPHK1 9380.0
CAB39 9379.0
ABI1 9373.0
E2F3 9367.0
WNT9B 9346.0
KIDINS220 9339.0
CXCR1 9335.0
OCRL 9323.0
HGS 9317.0
UBE2D1 9286.0
H2BC12 9280.0
LAMTOR1 9265.0
PTK6 9263.0
FMNL1 9262.0
SRF 9254.0
MYH9 9224.0
NEURL1 9207.0
FOXO4 9205.0
ADORA2B 9202.0
GNAT2 9195.0
TACC3 9187.0
PTPN2 9173.0
RGS3 9172.0
ZFYVE16 9147.0
BCL2L11 9144.0
PIK3CG 9128.0
PIK3CB 9126.0
DTX4 9123.0
RAPGEF3 9100.0
SPPL2A 9097.0
NEDD4L 9088.0
DTX2 9081.0
RGR 9055.0
PTPRO 9048.0
PDE8B 9045.0
PAK2 9042.0
TAX1BP3 9041.0
CSNK2A1 9040.0
RRAGA 9038.0
GPR37L1 9031.0
ARPC2 9016.0
NMT1 9007.0
HIF1A 9002.0
FFAR2 8986.0
H3-3A 8985.0
ARHGAP18 8978.0
ADCY4 8974.0
YWHAE 8971.0
ARHGEF17 8963.0
PIK3CD 8956.0
IL1RAP 8946.0
TNFRSF10B 8944.0
ADGRE5 8937.0
CDKN2B 8931.0
H3C15 8929.5
FZD1 8927.0
AMOTL1 8926.0
H2BC4 8925.0
ARHGAP30 8914.0
PPM1A 8912.0
ACTR2 8895.0
PSAP 8894.0
H2AC20 8893.0
LAMTOR5 8889.0
KLC1 8888.0
OXER1 8883.0
ACTR3 8873.0
KMT2D 8863.0
NCKAP1 8861.0
FGD3 8856.0
ASH2L 8855.0
MAPKAPK2 8852.0
FKBP1A 8827.0
GRK6 8816.0
AGO1 8810.0
AP2M1 8799.0
GALNT3 8797.0
LAMB3 8786.0
FADD 8785.0
GPR35 8778.0
SPINT1 8770.0
PSMD9 8766.0
CNR1 8753.0
STAT5B 8742.0
P2RY13 8741.0
RLN3 8732.0
CDC42EP2 8731.0
ARPC3 8726.0
CHUK 8723.0
B9D2 8721.0
PSME3 8716.0
PDPK1 8710.0
WIPF2 8699.0
ROCK1 8695.0
TFDP1 8682.0
GAB1 8670.0
KDM4A 8649.0
UBE2D3 8641.0
PDGFC 8634.0
MYH10 8632.0
PIP5K1B 8592.0
XCR1 8581.0
AKAP13 8579.0
PRKCB 8577.0
TACR2 8565.0
DHRS9 8558.0
KDM1B 8552.0
OR7A5 8530.0
DUSP3 8510.0
GGA3 8491.0
PPP1R12B 8489.0
RBCK1 8466.0
EPS15L1 8461.0
PSMB7 8460.0
F2RL1 8457.0
RAB4B 8449.0
IQGAP2 8437.0
OR52A1 8426.0
ATP6V0E1 8417.0
VAV3 8413.0
TRIB1 8411.0
AKT1S1 8410.0
NOTCH2 8400.0
PFN1 8397.0
ZDHHC7 8380.0
OR7C1 8361.0
GNAI3 8344.0
CDC42 8342.0
MAPK6 8326.0
FLNA 8318.0
HPN 8299.0
DYNC1LI1 8276.0
CSNK1A1 8266.0
PSMB5 8265.0
RRAGD 8243.0
OR2L2 8241.0
JAG1 8240.0
RAC2 8237.0
DGKG 8235.0
EVC 8213.0
ATP6V1E1 8198.0
KIF5B 8197.0
PRKCE 8190.0
PSMD1 8184.0
RGS2 8179.0
NCOA3 8176.0
ID1 8155.0
NCOR1 8153.0
XK 8147.0
NF1 8146.0
CREBBP 8143.0
PSMD2 8139.0
RGS14 8115.0
SHARPIN 8107.0
SOCS6 8074.0
ARHGDIA 8065.0
LIMK1 8062.0
AP2S1 8045.0
CCNK 8038.0
LAMTOR2 8006.0
PSMB3 8005.0
TAOK1 7977.0
LATS2 7972.0
IRAK1 7970.0
CLTB 7968.0
THBS3 7964.0
RHOB 7921.0
FAM13A 7917.0
GPSM2 7909.0
FABP5 7903.0
NCOA2 7898.0
MAPRE1 7885.0
SEL1L 7883.0
SMARCA4 7879.0
OR7A17 7862.0
PAFAH1B1 7857.0
POLR2A 7852.0
POU2F1 7849.0
ITGAV 7847.0
TMED5 7841.0
PSMA7 7840.0
FOSL1 7839.0
STAT5A 7833.0
DUSP1 7831.0
COL6A3 7824.0
GLI1 7808.0
PRKAG1 7805.0
VCP 7804.0
PPP1R12A 7801.0
OR10H5 7799.0
GDI1 7789.0
CHD8 7787.0
PSMD11 7775.0
SPOPL 7771.0
PHLPP1 7765.0
TBL1X 7764.0
B4GALT1 7763.0
PIP5K1C 7742.0
STARD8 7731.0
OR52K1 7725.0
PTPN12 7724.0
ITPR2 7716.0
SPTB 7702.0
FRS3 7701.0
RET 7671.0
MTMR4 7666.0
S1PR4 7664.0
STRADA 7659.0
KBTBD7 7650.0
GPSM3 7649.0
PSMD5 7646.0
DYNC1LI2 7644.0
COL9A3 7628.0
AATF 7612.0
DOCK1 7594.0
WNT3 7587.0
DLD 7581.0
PIK3R5 7579.0
PLCB2 7562.0
NEDD8 7558.0
HES1 7535.0
IL6R 7534.0
POFUT1 7528.0
SIRT6 7515.0
SEC13 7506.0
ARHGAP23 7484.0
PTPRU 7478.0
MEMO1 7465.0
PPP2CB 7451.0
CBX4 7438.0
STAM2 7431.0
PRKAR2A 7426.0
MCF2 7407.0
ARHGEF37 7406.0
UBE2M 7401.0
PSMB6 7399.0
ADCY7 7390.0
HDAC7 7388.0
ITGA2B 7387.0
PDE4A 7372.0
CSNK2A2 7341.0
RAP1A 7335.0
RASGRF1 7314.0
ARHGAP28 7309.0
PSMD6 7307.0
BAD 7263.0
JUNB 7257.0
NCF1 7245.0
BMPR2 7236.0
RALBP1 7224.0
MAP2K2 7222.0
VRK3 7206.0
USP8 7180.0
SPINT2 7173.0
CLTA 7164.0
PRKAB1 7148.0
GSK3B 7147.0
DIAPH1 7128.0
AHCYL1 7116.0
ATP6V1H 7104.0
MEF2D 7093.0
PSENEN 7091.0
STRN 7079.0
GNB4 7078.0
CXCL1 7072.0
OR2T33 7071.0
GPR65 7037.0
NGFR 7009.0
RNF111 7005.0
CLASP1 6986.0
LYPLA1 6982.0
RAP1B 6962.0
GDI2 6949.0
RANBP9 6938.0
IGF1R 6913.0
TNFRSF10D 6912.0
GATAD2A 6890.0
NCOA1 6885.0
ADM2 6884.0
NSL1 6874.0
DGKD 6870.0
SKIL 6851.0
PSMD12 6820.0
E2F1 6818.0
SCD 6815.0
USF1 6812.0
PPP2CA 6806.0
PDGFRB 6793.0
VPS35 6773.0
P2RY2 6771.0
H2BC5 6759.0
ITCH 6755.0
PPP1CB 6745.0
GTF2F1 6738.0
CXCR2 6720.0
DYNC1I2 6705.0
SH2B3 6700.0
SOX4 6690.0
CENPO 6682.0
CTNNBIP1 6674.0
ABHD6 6665.0
TAB3 6655.0
AR 6643.0
IER3 6632.0
ROCK2 6611.0
FGFR1 6607.0
PPP2R5D 6601.0
MKRN1 6583.0
ARHGAP44 6572.0
HEBP1 6552.0
ACKR3 6528.0
PTPN11 6524.0
PIK3R2 6511.0
ABCA1 6506.0
AKT1 6498.0
SMURF1 6481.0
KLC3 6451.0
GABRB3 6447.0
OR10G3 6434.0
PARD3 6422.0
ACKR2 6403.0
OXGR1 6399.0
GPR83 6364.0
USP9X 6344.0
SAG 6334.0
PKN1 6333.0
TNS4 6321.0
SMAD2 6291.0
NLN 6276.0
USP7 6259.0
GTF2F2 6257.0
RASA1 6250.0
APP 6245.0
HDAC8 6235.0
CDC73 6229.0
PIP5K1A 6224.0
NRP1 6221.0
BRAP 6218.0
ANOS1 6211.0
ADORA3 6204.0
CUL3 6200.0
VCL 6193.0
H2BC17 6188.0
VPS26A 6176.0
FFAR3 6167.0
ARHGAP31 6165.0
OR5A1 6162.0
PDE4C 6151.0
PDK4 6148.0
UBC 6135.0
KRAS 6132.0
ABL1 6127.0
PPP3CB 6126.0
H2BC11 6121.0
CDC37 6119.0
SHOC2 6108.0
PCSK5 6103.0
ARAF 6089.0
AGO2 6087.0
LRRK2 6086.0
GPR20 6069.0
EPS15 6059.0
PAG1 6054.0
MDM2 6043.0
CRHBP 6036.0
USF2 6027.0
PTGFR 6017.0
LAMTOR4 6002.0
DNM1 5998.0
RASAL2 5992.0
GATAD2B 5985.0
GNAS 5944.0
WDR83 5940.0
CENPE 5930.0
STRADB 5916.0
IFT122 5913.0
WWTR1 5902.0
RACGAP1 5897.0
SH3KBP1 5885.0
NLK 5881.0
PPP1CA 5880.0
CSNK2B 5876.0
NUP98 5874.0
BEX3 5862.0
MST1 5836.0
OR51L1 5803.0
TGFBR2 5802.0
CDC25C 5800.0
RXFP2 5770.0
SDC4 5724.0
KIF14 5707.0
MYL12B 5703.0
SYVN1 5702.0
PSMD8 5687.0
OPRD1 5678.0
ZNF217 5674.0
F2RL2 5667.0
PRKAR1B 5653.0
VEGFA 5648.0
CDK9 5620.0
POLR2J 5598.0
VEGFC 5567.0
PPP3R1 5564.0
CHN2 5539.0
CDKN1A 5537.0
TGFB1 5504.0
AKT2 5502.0
OR2B11 5488.0
SLC38A9 5485.0
PDE8A 5482.0
HDAC11 5471.0
GPR132 5460.0
NFKBIA 5457.0
ELMO1 5455.0
BAX 5446.0
H2AC6 5440.0
HDAC3 5437.0
KCTD6 5411.0
PLXNB1 5405.0
PLK1 5400.0
ARHGAP11B 5391.0
LAMTOR3 5383.0
GFAP 5346.0
TMED2 5345.0
PDGFA 5341.0
GNA13 5302.0
EGF 5267.0
CBX6 5259.0
TAX1BP1 5257.0
CRKL 5250.0
CAV2 5249.0
MC1R 5246.0
DRD4 5243.0
CRHR2 5235.0
CPT1A 5231.0
ANXA1 5228.0
PDK3 5227.0
E2F4 5213.0
PSMA6 5209.0
YWHAZ 5202.0
PPP2R1A 5189.0
FZD2 5116.0
POLR2E 5109.0
RAPGEF1 5102.0
OR2W3 5077.0
LTB4R2 5031.0
APC 5030.0
OR2AT4 5021.0
SERPINE1 5005.0
OR6Y1 4990.0
KREMEN2 4978.0
TGFBR1 4966.0
BCL2L1 4964.0
PSMC6 4959.0
PTPRA 4955.0
RETSAT 4940.0
NRAS 4907.0
UTS2 4904.0
PDE6D 4902.0
ZRANB1 4897.0
CXCL3 4877.0
RANBP10 4868.0
TBL1XR1 4852.0
PCSK6 4846.0
TRIO 4828.0
PSMC1 4827.0
OR1M1 4816.0
RHOBTB1 4769.0
SPTBN5 4732.0
YWHAB 4721.0
DLGAP5 4705.0
SOCS1 4688.0
TRAF6 4673.0
CDC20 4670.0
C5 4661.0
PDE6G 4656.0
SCUBE2 4649.0
THBS1 4645.0
RHOC 4639.0
MAPKAP1 4588.0
KLK2 4578.0
CENPF 4564.0
SMC1A 4551.0
PSMC2 4543.0
BIRC5 4541.0
TBXA2R 4539.0
HNRNPM 4537.0
PBX1 4529.0
ARHGAP4 4490.0
PTCRA 4488.0
GNG3 4481.0
REEP5 4480.0
OPN3 4474.0
OR4D9 4465.0
CX3CR1 4448.0
NDE1 4430.0
JAK2 4428.0
CASP3 4426.0
RHEB 4425.0
OR8A1 4412.0
SSTR2 4394.0
STARD13 4392.0
RPS6KA2 4384.0
H2AZ1 4378.0
BRAF 4367.0
ARHGAP6 4353.0
CDK8 4340.0
ECT2 4330.0
GNG8 4328.0
TSC2 4311.0
PSMD3 4297.0
LRP2 4295.0
WNT2B 4289.0
GRM6 4280.0
ADORA2A 4267.0
PSMF1 4259.0
POLR2F 4256.0
LRP12 4248.0
INSL3 4182.0
POLR2G 4175.0
ARHGEF12 4165.0
MAF1 4163.0
GUCY2D 4154.0
NF2 4139.0
OR5AU1 4128.0
SMPD2 4121.0
RFNG 4095.0
TCF4 4088.0
NPFFR1 4087.0
SRMS 4071.0
SPTA1 4063.0
WNT4 4058.0
MAP3K7 4043.0
ATP2A1 3981.0
SUCNR1 3964.0
OR6C75 3963.0
RBX1 3957.0
ARRB1 3956.0
QRFP 3955.0
GALR1 3939.0
RXFP4 3938.0
CSNK1G2 3936.0
OR5AS1 3917.0
PDE4D 3911.0
AKR1C1 3910.0
INCENP 3884.0
SPRY2 3882.0
VWF 3870.0
POMC 3862.0
USP15 3819.0
SOX6 3816.0
ATP6V1F 3811.0
IL33 3789.0
TCF7L1 3775.0
PSMD13 3766.0
F11R 3762.0
NRIP1 3702.0
OR2A5 3677.0
CXCL2 3656.0
ATP2A3 3651.0
F2RL3 3631.0
DEPDC1B 3627.0
RCVRN 3616.0
OXTR 3597.0
PRICKLE1 3576.0
VPS29 3562.0
KAT5 3557.0
RDH16 3544.0
PPP3CA 3538.0
SPRED1 3532.0
CETP 3531.0
DNM3 3523.0
TNKS2 3514.0
FZD4 3498.0
SEM1 3454.0
SKA1 3453.0
AVPR2 3452.0
RCC2 3388.0
ERCC6L 3386.0
HDAC5 3369.0
ARHGAP11A 3359.0
SNW1 3347.0
TSHR 3315.0
CALCRL 3305.0
WASL 3297.0
TIAM2 3254.0
ST3GAL6 3223.0
RIPK1 3206.0
RASGEF1A 3199.0
OR7D4 3168.0
MADD 3143.0
WIPF1 3137.0
GNG2 3124.0
JUN 3122.0
PSMA1 3111.0
CIT 3097.0
CFTR 3091.0
KNL1 3066.0
ABHD17C 3057.0
COL4A2 3049.0
ARF6 3007.0
ARHGAP25 3004.0
INTU 2989.0
NTRK3 2984.0
GREB1 2958.0
ITGB3 2944.0
AP2B1 2910.0
ARHGEF6 2908.0
CTBP1 2903.0
DRAP1 2901.0
PKN3 2892.0
CMKLR1 2883.0
CASR 2882.0
DYNC1I1 2879.0
MTA2 2877.0
CKAP5 2872.0
NFKB1 2860.0
RXRB 2848.0
RPS6KB2 2842.0
EIF4EBP1 2825.0
RHOQ 2797.0
FOS 2787.0
F2R 2762.0
VAV2 2755.0
SPC24 2754.0
RDH11 2740.0
PDE2A 2733.0
SCRIB 2722.0
BIRC2 2697.0
SGO1 2692.0
PIK3R3 2676.0
PRKG1 2673.0
FRK 2672.0
TFF3 2663.0
CBX8 2624.0
P2RY12 2608.0
HCAR3 2573.0
APH1A 2563.0
ATF1 2556.0
AGO3 2552.0
GPS2 2541.0
PCP2 2540.0
CAMK2G 2528.0
TRIB3 2492.0
GNG4 2481.0
PDE11A 2479.0
H2BC15 2474.0
CTNND1 2473.0
PPP1R15A 2469.0
CENPA 2464.0
ADCY2 2455.0
BCO2 2453.0
APOE 2448.0
HDAC10 2431.0
SRGAP3 2421.0
YBX1 2418.0
PRKAA1 2409.0
PRC1 2399.0
MOB1B 2393.0
AREG 2386.0
TCF12 2381.0
CHRM5 2366.0
NAB1 2340.0
IL1RL1 2334.0
SDC2 2325.0
FFAR4 2304.0
SREBF1 2292.0
MAP2K5 2256.0
STAG2 2247.0
CAV1 2229.0
ROR1 2194.0
OR2B6 2185.0
WNT5B 2169.0
GTF2A2 2140.0
LAMA4 2136.0
PIK3CA 2133.0
PTENP1 2128.0
SPRED3 2117.0
OR1D2 2108.0
CXXC4 2085.0
PSMD7 2084.0
OR5A2 2070.0
HBEGF 2064.0
KAT2B 2054.0
STK4 2051.0
CASP2 2017.0
POLR2L 2016.0
KIF2C 2011.0
PTGER2 1998.0
REEP1 1996.0
MGLL 1993.0
TRPC6 1988.0
AURKB 1985.0
STRAP 1981.0
REEP3 1977.0
TAB2 1975.0
RGS17 1940.0
MYL9 1931.0
FSTL1 1916.0
FNTB 1909.0
GNAT1 1893.0
MAD1L1 1882.0
RDH5 1861.0
OR2H2 1855.0
SFN 1840.0
PLIN1 1830.0
PSME4 1818.0
EGR3 1815.0
NELFB 1812.0
LEPR 1797.0
GABRG2 1791.0
MTOR 1777.0
WLS 1764.0
PSMB2 1760.0
IKBKB 1759.0
TAB1 1754.0
RRAGC 1745.0
COL9A2 1737.0
WNT9A 1709.0
DYNC1H1 1705.0
TAS2R14 1698.0
DLG2 1666.0
EIF4E 1661.0
UTS2B 1644.0
ELF3 1557.0
FUZ 1537.0
DYNLL1 1530.0
BCR 1529.0
REST 1524.0
GNGT2 1513.0
LAMA1 1497.0
MMP7 1494.0
FCER2 1492.0
OR2M3 1475.0
PGF 1432.0
WNT6 1409.0
OR2V2 1408.0
TSC1 1403.0
CDK5R1 1363.0
OR14J1 1336.0
GUCA1B 1331.0
HNRNPF 1319.0
ARHGEF1 1282.0
MYLK 1267.0
FAS 1260.0
NPHP4 1250.0
TF 1246.0
ADGRE3 1240.0
RDH13 1227.0
LFNG 1213.0
USP34 1199.0
PDE3A 1158.0
RGS6 1148.0
PIP4K2C 1118.0
IQGAP3 1051.0
ESRP2 1043.0
FLRT2 1038.0
UBB 1026.0
OR4E1 1023.0
NR3C1 1021.0
ADRA2A 1007.0
CASP10 1005.0
BUB1 1004.0
RGS18 979.0
ARHGAP21 976.0
NR1H3 954.0
ERLEC1 946.0
PSMD14 941.0
GNAL 939.0
OR2G6 938.0
PSMC3 916.0
STAM 907.0
RGS12 902.0
LPAR1 894.0
OR10A6 891.0
RASA2 864.0
HCAR2 859.0
RGS9 839.0
TAS2R20 765.0
LAMA5 751.0
PDE7B 747.0
CENPP 687.0
EVC2 686.0
RTP5 663.0
HDAC1 650.0
RPS6KA3 649.0
PSMB4 642.0
OR4K17 634.0
HSD17B1 623.0
PSMC4 605.0
ERBB3 599.0
GNAI1 579.0
PIN1 577.0
SDC3 564.0
PPP1CC 519.0
CTTN 514.0
EEPD1 511.0
CBFB 503.0
HCAR1 481.0
OPRM1 433.0
PKN2 418.0
PTK2 388.0
PIP4K2A 379.0
GAS8 368.0
XIAP 365.0
ADCY6 363.0
TAS2R3 319.0
TNRC6A 318.0
CDCA8 310.0
OR56A1 306.0
TNRC6B 301.0
H2BU1 298.0
OPHN1 294.0
CHD4 290.0
RHPN2 262.0
RNF2 248.0
HDAC6 243.0
KSR2 229.0
PLG 218.0
LPAR5 217.0
ABCG8 214.0
OR1I1 213.0
DACT1 206.0
PTPN3 190.0
ICMT 133.0
OR14L1P 91.0
PPP2R1B 89.0
ERBIN 87.0
SMAD7 52.0
DERL2 50.0
TNKS 15.0
GOLGA7 14.0
ADRB1 3.0
TNFSF10 2.0
TLR9 -36.0
LAMB2 -47.0
CHD1 -50.0
ARHGEF26 -56.0
CAB39L -66.0
RNF31 -95.0
GABBR1 -102.0
ACTA2 -159.0
IL6ST -192.0
RELA -204.0
PDHX -213.0
SPTBN2 -220.0
STK11 -238.0
AHCTF1 -241.0
EREG -249.0
CENPI -272.0
TLE1 -278.0
TJP1 -300.0
CDH1 -307.0
LRRC7 -340.0
KIF18A -394.0
MT-RNR2 -408.0
PSMB8 -438.0
TRIM33 -473.0
ARHGEF7 -477.0
TAS2R30 -490.0
POLR2C -494.0
SEPTIN7 -557.0
OTULIN -565.0
AXL -591.0
CPT1B -612.0
ZW10 -627.0
CCNT2 -632.0
PTPN7 -645.0
MCHR1 -651.0
ATF2 -657.0
RASAL1 -658.0
FER -690.0
REEP2 -742.0
DNAL4 -764.0
CYFIP2 -775.0
LEO1 -778.0
FGFRL1 -781.0
PMF1 -800.0
PML -815.0
GNA12 -817.0
OR5AN1 -854.0
PDK1 -862.0
GNAO1 -863.0
ARHGAP12 -877.0
IL3RA -895.0
LIN7B -933.0
NCBP1 -942.0
DIAPH3 -961.0
MED1 -971.0
DUSP10 -973.0
ATN1 -975.0
SPARC -1002.0
ARHGEF38 -1061.0
MLST8 -1064.0
DGKQ -1073.0
RBBP5 -1075.0
TRRAP -1100.0
RPTOR -1137.0
RANBP2 -1141.0
FRS2 -1144.0
CENPN -1151.0
CGN -1192.0
GTF2A1 -1202.0
IKZF1 -1225.0
CXCR4 -1239.0
EPGN -1241.0
CALM1 -1245.0
CCR5 -1251.0
MAPK12 -1261.0
SPRY1 -1274.0
TAS1R3 -1306.0
FBXW7 -1315.0
DHRS4 -1336.0
TNF -1341.0
SOX13 -1342.0
S100B -1351.0
GFRA2 -1359.0
WASF3 -1364.0
APOM -1386.0
IFT57 -1391.0
DUSP5 -1402.0
ADCY5 -1417.0
USP13 -1429.0
PRKAR2B -1442.0
KHDRBS1 -1443.0
COL4A4 -1448.0
PSPN -1490.0
GNRH1 -1528.0
HSPB1 -1544.0
CD86 -1606.0
GRK4 -1625.0
ARHGAP33 -1659.0
RAB4A -1669.0
PPID -1685.0
GRM2 -1714.0
PIK3C3 -1718.0
HRH4 -1724.0
INPP5B -1747.0
FASN -1777.0
COL4A3 -1796.0
FGFBP2 -1815.0
FN1 -1829.0
UHMK1 -1859.0
DLAT -1870.0
BAIAP2 -1877.0
PRKAG2 -1916.0
CLASP2 -1947.0
FGF23 -1952.0
PPBP -1960.0
NUF2 -1978.0
GPR161 -1982.0
PAQR3 -2011.0
SQSTM1 -2046.0
GRAP2 -2088.0
PIK3R4 -2097.0
S1PR5 -2104.0
DUSP4 -2116.0
PF4 -2122.0
A2M -2133.0
WWC1 -2138.0
RGS5 -2161.0
INHBA -2173.0
ARHGAP35 -2201.0
FOSB -2206.0
AVPR1A -2221.0
WNT8B -2225.0
RHOT2 -2229.0
MYH11 -2243.0
NUP37 -2275.0
JUND -2283.0
TNFAIP3 -2285.0
KTN1 -2306.0
LATS1 -2310.0
DGKZ -2312.0
BCL9 -2351.0
DGKH -2353.0
PHC3 -2377.0
PTGER3 -2397.0
MYO9A -2406.0
PRKCA -2408.0
RIPK2 -2451.0
DUSP7 -2452.0
RAMP1 -2465.0
NEURL1B -2466.0
GNRHR2 -2474.0
PDHB -2499.0
ALDH8A1 -2503.0
PSMD10 -2515.0
FNTA -2524.0
KPNA2 -2535.0
BRK1 -2561.0
OR52N4 -2575.0
CDK1 -2593.0
PPP2R5E -2595.0
ARHGEF10 -2615.0
FLT4 -2628.0
PTCH1 -2645.0
RAC3 -2651.0
RRAGB -2658.0
JUP -2668.0
NR4A1 -2672.0
GNAZ -2679.0
STUB1 -2688.0
OR7D2 -2723.0
HTR7 -2724.0
NSMAF -2735.0
PLPPR3 -2755.0
PSMA4 -2764.0
BUB1B -2766.0
GNA11 -2784.0
TNFRSF10A -2801.0
PSMA2 -2823.0
OR2M4 -2828.0
PTBP1 -2842.0
YES1 -2846.0
ADCY9 -2860.0
CUL5 -2872.0
GPBAR1 -2886.0
S1PR3 -2889.0
NCK2 -2908.0
DUSP8 -2914.0
DEPDC7 -2922.0
ATP6V1C2 -2926.0
CBX2 -2958.0
UCN -2962.0
FGFBP3 -2969.0
SOS1 -2983.0
AXIN1 -2986.0
CRABP2 -2987.0
ESR1 -3021.0
GPNMB -3026.0
IFT88 -3034.0
DUSP6 -3055.0
ARHGEF18 -3061.0
ITGB1 -3073.0
OR10AC1 -3075.0
CDKN1B -3127.0
ADRB2 -3128.0
ARAP2 -3156.0
CCL4 -3160.0
KIF7 -3174.0
ARL2 -3181.0
DAAM1 -3188.0
RAD21 -3191.0
TAS2R4 -3207.0
XPO1 -3214.0
SMAD5 -3215.0
SAV1 -3250.0
CXCL8 -3280.0
MST1R -3290.0
RCE1 -3302.0
GPC1 -3369.0
KDM4C -3380.0
POLR2B -3384.0
RGS10 -3391.0
C3 -3394.0
DAB2IP -3400.0
PDE6A -3411.0
PPP1R14A -3415.0
LAMA2 -3418.0
NUP85 -3427.0
ARHGAP22 -3431.0
GAS1 -3435.0
PPP5C -3445.0
UBA52 -3490.0
IFT52 -3507.0
GRK5 -3511.0
TIAM1 -3517.0
ARHGAP8 -3552.0
NMUR1 -3555.0
PTCH2 -3576.0
PSMB1 -3610.0
CDK2 -3614.0
PDHA1 -3634.0
SMAD4 -3639.0
HSPG2 -3657.0
NRG4 -3673.0
VIPR2 -3674.0
ITPR1 -3676.0
RARG -3682.0
CCNE1 -3688.0
NCKIPSD -3692.0
ITGA2 -3700.0
RING1 -3707.0
MXD4 -3719.0
PTGER4 -3724.0
GPR25 -3734.0
GZMB -3740.0
TIA1 -3757.0
EZH2 -3766.0
NTRK1 -3793.0
CCND1 -3813.0
USP21 -3859.0
LRP5 -3864.0
CCNT1 -3880.0
FGF22 -3881.0
ATP6V1E2 -3894.0
GNG11 -3895.0
POLR2I -3929.0
OR1A1 -3932.0
AMH -3947.0
SKI -3963.0
NAB2 -3964.0
CREB1 -3977.0
EGR1 -4009.0
HSP90AA1 -4016.0
PSMB10 -4050.0
STAG1 -4051.0
DOCK7 -4084.0
METAP2 -4086.0
ABHD17A -4101.0
ID3 -4133.0
SPOP -4141.0
ARHGAP39 -4144.0
S1PR1 -4161.0
DISP2 -4164.0
BTRC -4212.0
ABHD17B -4235.0
KLC4 -4248.0
SALL4 -4294.0
RDH10 -4306.0
CENPL -4320.0
WNT10A -4336.0
LINC01139 -4345.0
SFPQ -4358.0
SPPL2B -4389.0
SHC2 -4426.0
MTA1 -4442.0
ZWINT -4458.0
CNKSR2 -4467.0
MYB -4488.0
TIAL1 -4501.0
CENPU -4507.0
PPEF1 -4518.0
FGFR4 -4539.0
PSMC5 -4553.0
PLCB1 -4559.0
CD19 -4586.0
CCDC88C -4600.0
YWHAQ -4624.0
DAGLA -4626.0
CCL5 -4627.0
P2RY6 -4636.0
DVL1 -4637.0
LGR4 -4638.0
MAPK11 -4641.0
ZWILCH -4661.0
PARD6A -4681.0
NUDC -4710.0
MIB2 -4725.0
ATP6V1G1 -4775.0
TERT -4776.0
MDK -4787.0
PTGES3 -4805.0
ADAM12 -4810.0
CASP8 -4824.0
ABHD12 -4829.0
NMB -4855.0
GNB5 -4864.0
ARHGEF35 -4866.0
WDR35 -4883.0
MYLIP -4888.0
AKR1C3 -4889.0
DYNLL2 -4904.0
POLR2K -4907.0
NOXA1 -4914.0
KHDRBS2 -4927.0
FKBP4 -4937.0
MAMLD1 -4969.0
EDN1 -5002.0
PNOC -5016.0
SSTR3 -5020.0
CNR2 -5060.0
ARHGAP15 -5079.0
TRPC3 -5092.0
WNT10B -5109.0
HHAT -5136.0
YY1 -5142.0
NCAM1 -5143.0
ZNRF3 -5166.0
PPP2R5C -5198.0
POGLUT1 -5202.0
LGR6 -5208.0
CENPC -5210.0
FYN -5211.0
PTGDR2 -5227.0
ST3GAL3 -5250.0
PEA15 -5261.0
RICTOR -5264.0
RTP4 -5266.0
MIB1 -5272.0
HRAS -5273.0
JAG2 -5287.0
DOCK3 -5299.0
DSN1 -5307.0
SUZ12 -5320.0
GPSM1 -5339.0
NUP133 -5346.0
PRKCI -5349.0
MEN1 -5364.0
PRDM4 -5370.0
PDGFD -5417.0
ANGPT1 -5449.0
KLC2 -5453.0
STAP2 -5456.0
NAPEPLD -5471.0
SKA2 -5481.0
IFT172 -5486.0
SH2B1 -5489.0
SGO2 -5502.0
PRKAB2 -5520.0
LPAR3 -5541.0
WNT1 -5571.0
DNAJB1 -5574.0
H2AZ2 -5576.0
RBBP4 -5599.0
OR2A1 -5626.0
DVL2 -5637.0
BMPR1A -5641.0
ARHGEF9 -5671.0
ARHGEF39 -5711.0
H2BC9 -5728.0
FZD7 -5729.0
AGRN -5730.0
PTGDR -5739.0
OTUD3 -5750.0
OTUD7B -5751.0
GRPR -5774.0
TBP -5776.0
GHRL -5816.0
FGFR2 -5834.0
SMURF2 -5858.0
XCL2 -5876.0
GNG7 -5880.0
ELK1 -5884.0
PAK3 -5908.0
CDC14B -5922.0
DLG1 -5924.0
DYNC2H1 -5932.0
SCAI -5942.0
MBD3 -5950.0
MOV10 -5956.0
FZD3 -5964.0
GPR68 -5969.0
TPH1 -5977.0
NDC80 -5999.0
PRKCZ -6016.0
MEF2C -6025.0
IRS1 -6033.0
GPC2 -6039.0
PDK2 -6050.0
PTPRS -6062.0
RGS1 -6076.0
S1PR2 -6086.0
SMC3 -6091.0
TRIP10 -6094.0
GNB3 -6125.0
PORCN -6126.0
RASGRP2 -6127.0
ITPR3 -6139.0
ERBB2 -6142.0
CHEK1 -6143.0
CDON -6145.0
FZD8 -6149.0
FAM13B -6151.0
NFATC1 -6177.0
PLAT -6194.0
PIP4K2B -6196.0
POLR2H -6200.0
RAG1 -6228.0
FGF2 -6231.0
SH2D2A -6241.0
MAPKAPK5 -6258.0
JAK1 -6261.0
SGK1 -6264.0
SKP1 -6297.0
RPS6KB1 -6316.0
PHB -6317.0
AAMP -6320.0
RASAL3 -6333.0
TTC21B -6366.0
PTGIR -6377.0
RALA -6392.0
PSEN2 -6393.0
SRC -6396.0
CXXC5 -6431.0
PSMA3 -6433.0
SCT -6447.0
KNTC1 -6520.0
CHD3 -6523.0
CSNK1E -6526.0
ARHGAP17 -6549.0
ZDHHC21 -6561.0
ATP6V0A2 -6587.0
DDX5 -6600.0
EGR2 -6603.0
SHC3 -6615.0
EFCAB7 -6619.0
NBEA -6636.0
RBFOX2 -6652.0
CYP4V2 -6662.0
CENPK -6671.0
E2F5 -6685.0
RACK1 -6689.0
CAMKMT -6707.0
SMPD3 -6708.0
RUNX3 -6737.0
RASGRP3 -6748.0
CCR8 -6752.0
CXCL5 -6756.0
PRR5 -6787.0
EED -6816.0
KIF2A -6844.0
POLR2D -6856.0
SLC24A1 -6865.0
HDAC2 -6871.0
CILP -6897.0
ARHGAP10 -6902.0
TGIF1 -6918.0
CCNC -6937.0
KIF5A -6961.0
BCL2 -6977.0
MUC20 -6993.0
CENPQ -7019.0
OR2I1P -7064.0
RBL1 -7071.0
FPR3 -7103.0
EEF2K -7105.0
MAML2 -7122.0
ARHGAP42 -7129.0
MTA3 -7142.0
RHOBTB2 -7166.0
NOS3 -7169.0
FASLG -7230.0
LRP6 -7232.0
NRG1 -7233.0
MCF2L -7236.0
TNRC6C -7302.0
RGS16 -7308.0
KDM1A -7314.0
CENPT -7317.0
HNRNPH1 -7320.0
PSME2 -7327.0
FGF7 -7330.0
TRADD -7336.0
MKS1 -7391.0
VIPR1 -7404.0
KISS1R -7425.0
RALGDS -7432.0
ARHGAP32 -7436.0
DUSP2 -7443.0
XCL1 -7448.0
COL6A2 -7450.0
WNT16 -7459.0
TRAF2 -7465.0
PSMA5 -7476.0
GOPC -7500.0
RASA4 -7530.0
RAMP3 -7587.0
MFNG -7604.0
GIPR -7641.0
NET1 -7666.0
STMN1 -7679.0
IL2RA -7681.0
MAD2L1 -7701.0
IL2RG -7711.0
ESR2 -7755.0
CYSLTR1 -7761.0
SORCS3 -7776.0
PSME1 -7778.0
CYSLTR2 -7793.0
PDE4B -7796.0
SYNGAP1 -7809.0
GPC4 -7831.0
METAP1 -7855.0
SMAD3 -7868.0
WDR19 -7885.0
CXCR5 -7898.0
UCHL5 -7902.0
PPARD -7903.0
MATK -7917.0
MIR25 -7926.0
PMEPA1 -7984.0
CCR9 -7989.0
NRP2 -8032.0
KALRN -8077.0
FMNL3 -8078.0
SMAD9 -8084.0
ABCG1 -8093.0
RUVBL1 -8098.0
CLIP3 -8124.0
LAMC3 -8137.0
SPTBN1 -8138.0
HNRNPA1 -8155.0
BCL9L -8159.0
DLL1 -8167.0
ABI2 -8174.0
EIF4B -8190.0
TAS2R5 -8211.0
DUSP16 -8213.0
CD80 -8215.0
PELP1 -8232.0
CNKSR1 -8238.0
DLG3 -8241.0
IL5RA -8245.0
ITGB3BP -8253.0
ITGA3 -8259.0
CCR10 -8280.0
NUP107 -8285.0
EBAG9 -8302.0
CCL3 -8305.0
GPAM -8319.0
CNOT6L -8322.0
THBS4 -8348.0
BMI1 -8355.0
NUP160 -8357.0
NUP43 -8368.0
RBBP7 -8382.0
ARHGEF3 -8386.0
PRMT1 -8388.0
PARP1 -8391.0
TFDP2 -8396.0
IFT140 -8401.0
TULP3 -8418.0
FZD6 -8438.0
CBY1 -8454.0
PYGO2 -8455.0
ARHGEF5 -8463.0
FGF9 -8476.0
CENPM -8484.0
DTX1 -8499.0
PSMB9 -8503.0
HTR6 -8521.0
ARL4C -8524.0
AXIN2 -8546.0
OR4D1 -8552.0
CHN1 -8566.0
PHC1 -8578.0
OR2A7 -8591.0
RANGAP1 -8592.0
OBSCN -8610.0
CCR3 -8617.0
COL6A1 -8623.0
DGKE -8629.0
AMER1 -8632.0
GLI3 -8649.0
MIS12 -8664.0
RHOF -8679.0
HDAC9 -8695.0
P2RY11 -8701.0
RPGRIP1L -8703.0
TGIF2 -8725.0
PDE6B -8727.0
AMOT -8757.0
TRAF1 -8760.0
ARHGEF19 -8770.0
ARHGEF10L -8789.0
PRKG2 -8799.0
AKT3 -8810.0
DGKA -8817.0
LPAR6 -8825.0
PIK3R1 -8831.0
CXCR3 -8838.0
MAPK8 -8929.0
SCMH1 -8966.0
NCK1 -8975.0
CXCL9 -9044.0
KAT2A -9063.0
PPP3CC -9067.0
DHRS3 -9073.0
WWOX -9080.0
RNF43 -9119.0
CDK4 -9130.0
PTPRK -9142.0
ATP6V1G2 -9143.0
PFN2 -9148.0
ARHGEF4 -9155.0
PDE3B -9157.0
CXCR6 -9159.0
TP53 -9170.0
HSP90AB1 -9172.0
RPS27 -9175.0
NEFL -9178.0
ACVR2B -9219.0
RHOH -9236.0
PRKX -9245.0
P2RY14 -9268.0
CENPH -9281.0
RASA3 -9306.0
RLN2 -9331.0
MYC -9357.0
RPS6KA5 -9386.0
RHPN1 -9389.0
RASGRP1 -9394.0
KANK1 -9399.0
RYK -9411.0
PLCG1 -9412.0
CUL1 -9420.0
PRKCQ -9424.0
KIF3A -9438.0
STAT1 -9448.0
OFD1 -9455.0
ATP6V0E2 -9456.0
SPTAN1 -9461.0
LAT -9470.0
VEGFB -9481.0
GPR15 -9491.0
CCR7 -9494.0
SPDL1 -9495.0
CCR4 -9533.0
SYDE2 -9555.0
LCK -9556.0
EVL -9560.0
PDGFB -9562.0
RASGRF2 -9563.0
SEH1L -9574.0
PDE7A -9584.0
SOX7 -9587.0
PRKCH -9600.0
BUB3 -9608.0
PLEKHG5 -9612.0
NCBP2 -9631.0
PHLPP2 -9640.0
IL2RB -9646.0
RPS6 -9699.0
RPS27A -9723.0
FOXO1 -9731.0
ZFYVE9 -9740.0
P2RY10 -9786.0
GPR18 -9804.0
MAGED1 -9821.0
TLE5 -9833.0
PEBP1 -9843.0
PRKACB -9863.0
CCL28 -9867.0
GPR150 -9869.0
GREM2 -9884.0
ARHGAP5 -9887.0
RDH14 -9902.0
KDM3A -9906.0
CAMK2D -9907.0
TLE2 -9911.0
DGKK -9915.0
NMT2 -9920.0
ICOS -9952.0
CYLD -9961.0
NOG -9965.0
ACVR2A -9974.0
ACVR1C -9984.0
WWP1 -9985.0
REEP6 -9988.0
LRIG1 -9995.0
TAGAP -10011.0
LEF1 -10027.0
BIRC3 -10039.0
RTKN -10047.0
TRAT1 -10049.0
CXCL10 -10060.0
GATA3 -10071.0
FLT3LG -10078.0
GPR183 -10091.0
GRAP -10095.0
THEM4 -10102.0
ARHGEF25 -10103.0
CCR6 -10108.0
KIT -10114.0
CAMK4 -10131.0
GPR55 -10132.0
ALDH1A1 -10134.0
TCF7 -10143.0
CDC14A -10145.0
WNT7A -10154.0
CD28 -10159.0


Regulation of expression of SLITs and ROBOs

Regulation of expression of SLITs and ROBOs
979
set Regulation of expression of SLITs and ROBOs
setSize 159
pANOVA 6.82e-17
s.dist -0.383
p.adjustANOVA 3.09e-15



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
ROBO3 -9694
RPS25 -9664
RPL22 -9659
NCBP2 -9631
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
ROBO3 -9694
RPS25 -9664
RPL22 -9659
NCBP2 -9631
RPS2 -9591
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
RPL27A -9048
RPS5 -9042
RPL10 -9031
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
UPF3A -8795
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
RPL29 -8621
RPS16 -8579
RPS14 -8541
PSMB9 -8503
RPS10 -8494
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
RPS28 -8083
RNPS1 -8030
GSPT2 -7995
RPS11 -7975
RPL38 -7968
RPL37 -7861
RPL27 -7810
RPS19 -7806
PSME1 -7778
RPL13 -7671
RPL41 -7561
RPL36 -7493
PSMA5 -7476
PSME2 -7327
RPL37A -6833
RPL9 -6821
RPS24 -6818
MAGOHB -6726
RPS15 -6703
RPL36AL -6646
RPSA -6629
PSMA3 -6433
RPL8 -6101
RPLP1 -6018
UPF3B -5843
LDB1 -4826
MAGOH -4678
PSMC5 -4553
PSMB10 -4050
RPL28 -3873
FAU -3618
PSMB1 -3610
UBA52 -3490
PABPC1 -2991
PSMA2 -2823
PSMA4 -2764
PSMD10 -2515
USP33 -2081
GSPT1 -2025
RPL39L -1661
RBM8A -1499
RPS26 -1154
NCBP1 -942
LHX4 -539
RPS27L -496
PSMB8 -438
CUL2 -38
DAG1 261
RPS4Y1 331
PSMC4 605
PSMB4 642
PSMC3 916
PSMD14 941
ROBO1 973
UBB 1026
UPF2 1281
EIF4A3 1507
PSMB2 1760
PSME4 1818
RPS9 1841
PSMD7 2084
PSMA1 3111
SEM1 3454
PSMD13 3766
RBX1 3957
PSMF1 4259
PSMD3 4297
PSMC2 4543
PSMC1 4827
PSMC6 4959
RPL3L 5150
PSMA6 5209
PSMD8 5687
RPL26L1 6001
UBC 6135
PSMD12 6820
ETF1 6835
ELOC 6974
PSMD6 7307
PSMB6 7399
ELOB 7435
PSMD5 7646
PSMD11 7775
PSMA7 7840
PSMB3 8005
PSMD2 8139
PSMD1 8184
PSMB5 8265
PSMB7 8460
SLIT1 8535
PSME3 8716
PSMD9 8766
CASC3 9610
PSMD4 10088
ZSWIM8 10300
EIF4G1 10506


Formation of the ternary complex, and subsequently, the 43S complex

Formation of the ternary complex, and subsequently, the 43S complex
397
set Formation of the ternary complex, and subsequently, the 43S complex
setSize 51
pANOVA 1.92e-16
s.dist -0.665
p.adjustANOVA 8.41e-15



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS3A -9834
RPS27A -9723
RPS6 -9699
RPS25 -9664
RPS2 -9591
EIF3B -9526
RPS20 -9413
RPS23 -9387
RPS3 -9298
RPS12 -9270
RPS27 -9175
RPS7 -9165
EIF3E -9049
RPS5 -9042
RPS15A -8883
RPS8 -8861
RPS13 -8724
RPS4X -8648
RPS29 -8637
RPS16 -8579

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS3A -9834
RPS27A -9723
RPS6 -9699
RPS25 -9664
RPS2 -9591
EIF3B -9526
RPS20 -9413
RPS23 -9387
RPS3 -9298
RPS12 -9270
RPS27 -9175
RPS7 -9165
EIF3E -9049
RPS5 -9042
RPS15A -8883
RPS8 -8861
RPS13 -8724
RPS4X -8648
RPS29 -8637
RPS16 -8579
RPS14 -8541
RPS10 -8494
EIF1AX -8383
RPS21 -8330
RPS18 -8321
RPS17 -8281
EIF3L -8255
RPS28 -8083
RPS11 -7975
RPS19 -7806
EIF3H -7091
RPS24 -6818
EIF3M -6817
RPS15 -6703
RPSA -6629
EIF3J -6448
EIF3F -5200
EIF3D -5158
EIF3C -4716
FAU -3618
EIF3G -2746
EIF3I -2580
EIF3K -2369
EIF2S1 -1649
EIF3A -1276
RPS26 -1154
RPS27L -496
RPS4Y1 331
EIF2S2 554
RPS9 1841
EIF2S3 2500


Metabolism of lipids

Metabolism of lipids
641
set Metabolism of lipids
setSize 625
pANOVA 5.63e-15
s.dist 0.183
p.adjustANOVA 2.4e-13



Top enriched genes

Top 20 genes
GeneID Gene Rank
PLBD1 11462
TNFAIP8L3 11461
GGT1 11459
PLB1 11453
PPARG 11451
ACOX2 11389
VDR 11370
PRKACA 11363
HSD3B7 11352
PLIN3 11351
CYP19A1 11333
GBA 11321
OLAH 11317
NCOR2 11217
CYP1B1 11182
TBXAS1 11179
ALOX5 11178
DGAT2 11173
MTMR3 11166
PLA2G15 11163

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PLBD1 11462
TNFAIP8L3 11461
GGT1 11459
PLB1 11453
PPARG 11451
ACOX2 11389
VDR 11370
PRKACA 11363
HSD3B7 11352
PLIN3 11351
CYP19A1 11333
GBA 11321
OLAH 11317
NCOR2 11217
CYP1B1 11182
TBXAS1 11179
ALOX5 11178
DGAT2 11173
MTMR3 11166
PLA2G15 11163
SBF2 11135
GALC 11109
ACSL1 11102
PLD1 11091
NEU1 11082
ACAA1 11076
ALDH3B1 11063
AGPAT2 11054
PGS1 10960
CD36 10947
CPT2 10925
PISD 10908
FADS1 10870
PTGR1 10862
GM2A 10846
CTSA 10842
LPCAT3 10827
ACOT8 10822
SEC24D 10803
ASAH1 10796
INPPL1 10780
PITPNM1 10765
RGL1 10752
MBOAT7 10742
TSPO 10650
PNPLA6 10643
BMX 10642
MTF1 10630
ARF1 10610
GLA 10595
SYNJ1 10567
ME1 10563
CYP4F8 10561
LTA4H 10541
FIG4 10489
NFYC 10461
GLTP 10432
ACSL4 10426
ACOX3 10360
ACER3 10352
PPT1 10327
NCOA6 10326
PNPLA2 10314
CARM1 10313
SQLE 10297
LPCAT2 10290
DHCR24 10280
ACOX1 10277
ACLY 10268
ARNT 10231
GLB1 10217
PLPP3 10216
ACSS3 10139
SUMF1 10121
HADHB 10113
RXRA 10073
ARSB 10041
PIK3R6 10025
DHRS7B 9980
ABHD5 9941
SGMS2 9919
TXNRD1 9890
ALOX5AP 9860
GK 9850
SREBF2 9844
ELOVL1 9841
CHPT1 9824
HMGCL 9821
PLIN2 9820
PLA2G4A 9803
EP300 9789
GPCPD1 9781
SGPL1 9740
CDK19 9729
SP1 9699
APOA2 9687
VAPA 9635
LPGAT1 9625
ACACA 9620
MBOAT2 9614
SPTLC2 9556
ACOT9 9554
ELOVL3 9553
PTEN 9545
NR1H2 9521
OSBPL2 9487
HPGD 9484
PECR 9472
ARF3 9465
FAR2 9451
PCYT1A 9450
MED13L 9444
FDFT1 9429
SEC24A 9414
CHKA 9404
SGMS1 9391
FAM120B 9384
FAR1 9382
SPHK1 9380
PTGES 9372
SPTLC1 9343
OCRL 9323
GBA2 9313
CYP51A1 9307
MTMR10 9300
PCTP 9236
IDI1 9233
ESRRA 9192
SLC25A20 9152
PIK3CG 9128
PIK3CB 9126
HMGCR 9117
ABHD3 9102
PHOSPHO1 9099
GPD2 9098
DHCR7 9064
CSNK2A1 9040
INPP5D 9020
SEC24C 8993
EHHADH 8968
PIK3CD 8956
PIAS4 8952
HSD17B4 8942
ACSL3 8896
PSAP 8894
PLD2 8890
MAPKAPK2 8852
STS 8843
ACAD10 8835
LBR 8834
CYP2C9 8833
CERT1 8831
ORMDL2 8759
MED20 8757
MED8 8643
ALB 8630
GDE1 8624
CRAT 8611
SRD5A1 8609
PIP5K1B 8592
B3GALNT1 8574
MED18 8563
ARSA 8456
GPAT3 8450
CERS2 8442
ALAS1 8407
MTMR14 8341
HACD1 8328
GPAT4 8292
ACOT13 8275
SLC10A2 8208
NCOA3 8176
NCOR1 8153
CREBBP 8143
MED25 8136
DBI 8125
ACADVL 8108
ABHD4 8047
MTMR6 8023
SAMD8 8012
ABCD1 7994
STARD3 7939
AGPAT3 7932
FABP5 7903
NCOA2 7898
CDS2 7856
NUDT19 7850
CYP4F3 7797
CYP1A2 7792
ARSD 7786
STARD5 7780
TBL1X 7764
OSBPL9 7755
PLA2R1 7747
PIP5K1C 7742
MED12 7718
SMARCD3 7698
LPCAT1 7696
HEXB 7695
GDPD3 7690
MTMR4 7666
PIK3R5 7579
ACHE 7553
AGPAT4 7542
UGCG 7482
AGPAT1 7471
HSD17B2 7409
SEC24B 7352
STARD3NL 7350
CSNK2A2 7341
PCYT1B 7276
SLC22A5 7274
ACOXL 7268
FADS2 7216
CRLS1 7193
FHL2 7159
RAB5A 7154
SEC23A 7129
ALOX15B 7127
PI4K2A 7125
ABCC3 7122
FABP2 7090
SPHK2 7067
TECRL 6989
DECR1 6978
GPX1 6961
SRD5A3 6925
ARNTL 6905
SAR1B 6893
NCOA1 6885
MBOAT1 6826
SLC25A1 6824
SCD 6815
HELZ2 6747
PPP1CB 6745
INSIG2 6701
NFYA 6667
VAC14 6616
ANGPTL4 6584
TMEM86B 6582
PNPLA8 6573
MED26 6537
STAR 6515
PIK3R2 6511
ABCA1 6506
MBTPS1 6492
SLC44A1 6488
OSBPL8 6483
ALOX12 6474
SMPD1 6417
PLD3 6346
FDPS 6299
PIP5K1A 6224
LIPH 5978
SLC27A1 5937
PPP1CA 5880
CSNK2B 5876
GNPAT 5765
INSIG1 5740
PLAAT2 5734
ELOVL5 5665
MED14 5610
KPNB1 5604
HSD11B2 5570
RAB14 5469
NSDHL 5461
HDAC3 5437
ABCC1 5410
ACBD5 5330
ACADS 5273
HTD2 5255
CPT1A 5231
GGT5 5204
SLC44A2 5180
DGAT1 5173
CDIPT 5123
PI4KA 4989
GSTM4 4951
SLC44A5 4884
PPARA 4862
TBL1XR1 4852
ACADL 4831
CERS6 4794
PPM1L 4767
MTMR9 4758
PIKFYVE 4728
CYP4F22 4727
HADHA 4715
GLIPR1 4675
INPP4A 4672
THRAP3 4646
MSMO1 4597
HSD17B11 4556
ACOT1 4485
MMUT 4382
STARD4 4366
CDK8 4340
HSD17B12 4318
PTGS1 4306
LRP2 4295
HACD4 4285
TAZ 4224
ACOT11 4190
ACAA2 4179
MED16 4162
ACBD7 4124
SMPD2 4121
GPX4 3999
MTMR12 3942
CSNK1G2 3936
CPTP 3933
AKR1C1 3910
HSD17B13 3901
PMVK 3864
POMC 3862
PLEKHA4 3822
RUFY1 3750
TNFAIP8L2 3688
MOGAT3 3614
PLEKHA6 3589
CERS5 3547
GPX2 3367
OSBPL1A 3364
PI4KB 3345
ARV1 3288
TIAM2 3254
ACSF3 3246
GLB1L 3217
CERS3 3213
MED11 3182
AGPS 3174
DEGS1 3135
MVD 3037
MVK 2992
CPNE3 2985
PTDSS2 2977
RXRB 2848
ACSM6 2747
PLEKHA2 2715
GPAT2 2684
MED22 2682
PIK3R3 2676
SCD5 2659
NUDT7 2574
GPS2 2541
SLC27A3 2521
FDXR 2505
TRIB3 2492
SREBF1 2292
PLA2G4D 2282
INPP5F 2254
STARD7 2241
CAV1 2229
DPEP2 2213
PIK3CA 2133
INPP5K 2072
SIN3B 2071
PRKD2 2014
MGLL 1993
MED23 1915
DPEP3 1876
PLIN1 1830
OSBP 1625
CYP7B1 1593
MTMR7 1541
HMGCS1 1443
MLYCD 1339
ASAH2 1238
MED24 1185
OSBPL6 1180
MED7 1178
AHR 1155
PIK3C2G 1144
PIP4K2C 1118
PRKD3 1059
MTM1 987
SLC27A5 971
NR1H3 954
FA2H 888
MID1IP1 870
MTMR1 632
MED13 630
HSD17B1 623
PEX11A 600
PPP1CC 519
PTPMT1 516
AACS 485
MED28 479
PTGS2 444
SC5D 441
PIP4K2A 379
CHKB 375
OXCT2 276
ENPP6 267
ARSG 247
PTGR2 152
STARD10 118
MBTPS2 112
CHD9 97
DEGS2 92
CEPT1 29
G0S2 17
MCAT -23
PPARGC1B -31
CBR4 -64
AKR1B15 -78
NRF1 -105
PLEKHA5 -131
SPTLC3 -158
PLA2G2D -265
HILPDA -510
NEU3 -511
VAPB -541
AMACR -556
PITPNM3 -568
CYP46A1 -583
CPT1B -612
LTC4S -624
GDPD1 -696
PITPNM2 -787
OSBPL5 -830
MED15 -911
SLC10A1 -944
MED1 -971
CBR1 -1044
ELOVL7 -1079
ETNK1 -1197
TNFRSF21 -1215
AHRR -1354
LCLAT1 -1384
ALDH3A2 -1453
ABCB4 -1460
MED9 -1496
PIK3C2A -1501
PTDSS1 -1529
ACSF2 -1572
ACSBG1 -1613
CPNE1 -1632
SUMO2 -1665
RAB4A -1669
PIK3C3 -1718
PPARGC1A -1762
ALOX12B -1769
FASN -1777
DECR2 -1824
MED19 -1831
ACAT1 -1835
ETNK2 -1853
UGT8 -1881
FITM1 -1897
GRHL1 -1905
PRKAG2 -1916
PLEKHA3 -1951
HEXA -1967
SCP2 -1980
NPAS2 -1986
FABP3 -2016
PIK3R4 -2097
SCAP -2217
PLAAT1 -2233
MED4 -2264
MCEE -2321
UBE2I -2356
PLPP2 -2373
PNPLA4 -2431
MED31 -2514
CYP2R1 -2532
GPD1 -2540
CYP27A1 -2606
MED17 -2648
ACER2 -2656
ELOVL6 -2691
PLEKHA8 -2709
MED30 -2845
SGPP1 -2870
ACSL5 -2964
MED27 -2978
PEMT -3022
MED21 -3045
PLAAT3 -3108
SPTSSA -3146
ECI1 -3149
SBF1 -3176
MTMR2 -3228
CDS1 -3232
LPIN3 -3276
PHYH -3554
MIGA2 -3595
PLA2G12A -3642
FDX2 -3645
MECR -3685
MED29 -3703
MTMR8 -3710
ACOT2 -3885
ORMDL1 -3898
PLA2G10 -3943
FDX1 -4167
ACP6 -4203
CERS4 -4243
TGS1 -4316
PNPLA7 -4407
NDUFAB1 -4616
ACOT4 -4737
AKR1C2 -4762
ACOT7 -4794
PTGES3 -4805
OSBPL10 -4872
PTGDS -4875
AKR1C3 -4889
ACBD4 -4932
ACBD6 -4933
PITPNB -4948
CLOCK -5087
SACM1L -5181
CPNE7 -5225
LPIN2 -5259
LSS -5301
PTGES2 -5466
PLPP6 -5472
PCCA -5495
PRKAB2 -5520
PCCB -5533
ACAD11 -5598
PLA2G4C -5649
LPCAT4 -5657
ACACB -5738
THEM5 -5745
PCYT2 -5747
TSPOAP1 -5749
GGPS1 -5852
GDPD5 -5937
PTPN13 -6043
CERK -6072
ARSJ -6097
LPIN1 -6134
PON2 -6138
ORMDL3 -6182
PIP4K2B -6196
HACD2 -6269
SLC27A2 -6278
PPT2 -6473
MFSD2A -6655
SMPD3 -6708
MED6 -6714
EBP -6764
SMPD4 -6771
ECHS1 -6827
MMAA -6835
ACAT2 -6884
CCNC -6937
TM7SF2 -7109
PLA2G6 -7168
CYP2J2 -7201
INPP5E -7239
ACADM -7323
OSBPL7 -7363
HSD17B8 -7412
FITM2 -7433
CYP2D6 -7481
CYP2U1 -7617
HSD17B7 -7639
DDHD1 -7662
LGMN -7705
SIN3A -7740
GPD1L -7794
SPTSSB -7818
PPARD -7903
BDH2 -7961
PLA2G4B -7971
SGPP2 -8015
SUMF2 -8041
LIPE -8128
ACER1 -8208
CUBN -8222
SELENOI -8239
TECR -8287
GPAM -8319
MORC2 -8366
FAAH -8414
MIGA1 -8433
ACSM3 -8447
RAN -8475
CYP27B1 -8534
MED10 -8535
TNFAIP8L1 -8554
OSBPL3 -8569
AGK -8639
PIK3R1 -8831
PRXL2B -8870
PLPP1 -8968
PIK3C2B -9076
SLC25A17 -9128
HADH -9191
RORA -9193
NR1D1 -9199
ESYT2 -9244
TNFAIP8 -9265
SYNJ2 -9322
CROT -9329
AGPAT5 -9340
DDHD2 -9460
ALOX15 -9484
PI4K2B -9565
HACL1 -9575
OXCT1 -9611
BDH1 -9616
HACD3 -9619
ESYT1 -9643
ECI2 -9676
PLAAT4 -9716
PLD6 -9733
CYP2E1 -9766
ACSL6 -9807
PRKACB -9863
AKR1B1 -9879
PLEKHA1 -9941
FAAH2 -9959
ARSK -10007
ELOVL4 -10029
NFYB -10059
KDSR -10061
EPHX2 -10075
THEM4 -10102
PLD4 -10109
INPP4B -10116


rRNA modification in the nucleus and cytosol

rRNA modification in the nucleus and cytosol
1350
set rRNA modification in the nucleus and cytosol
setSize 59
pANOVA 5.93e-15
s.dist -0.587
p.adjustANOVA 2.45e-13



Top enriched genes

Top 20 genes
GeneID Gene Rank
DKC1 -10139
NOP58 -10031
FBL -9942
NOL11 -9932
NAT10 -9828
WDR75 -9823
THUMPD1 -9782
UTP4 -9700
RPS6 -9699
DIMT1 -9652
NOP14 -9641
BMS1 -9626
RPS2 -9591
NOP56 -9444
WDR43 -9395
DDX47 -9334
RPS7 -9165
UTP15 -9156
WDR46 -9056
MPHOSPH10 -8840

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DKC1 -10139
NOP58 -10031
FBL -9942
NOL11 -9932
NAT10 -9828
WDR75 -9823
THUMPD1 -9782
UTP4 -9700
RPS6 -9699
DIMT1 -9652
NOP14 -9641
BMS1 -9626
RPS2 -9591
NOP56 -9444
WDR43 -9395
DDX47 -9334
RPS7 -9165
UTP15 -9156
WDR46 -9056
MPHOSPH10 -8840
EMG1 -8744
UTP6 -8616
RRP9 -8598
RPS14 -8541
SNU13 -8495
NOP2 -8307
PNO1 -8004
NOL6 -7834
KRR1 -7720
RCL1 -7690
DCAF13 -7564
UTP20 -7427
GAR1 -7407
HEATR1 -7278
IMP4 -7155
WDR3 -7016
IMP3 -6912
PDCD11 -6547
NHP2 -6535
PWP2 -5423
RRP7A -5246
WDR36 -5072
UTP3 -4821
DHX37 -4742
UTP14A -3323
UTP14C -2415
TRMT112 -2296
RRP36 -395
UTP11 -37
FCF1 453
TBL3 739
TSR3 1498
NOC4L 1606
DDX52 1795
RPS9 1841
UTP18 3850
DDX49 4083
NOP10 10379
SNORD3A 10596


Gene expression (Transcription)

Gene expression (Transcription)
442
set Gene expression (Transcription)
setSize 1326
pANOVA 1.11e-14
s.dist -0.126
p.adjustANOVA 4.43e-13



Top enriched genes

Top 20 genes
GeneID Gene Rank
RORC -10162
TCF7 -10143
CAMK4 -10131
NPM1 -10121
KIT -10114
GLS -10099
NDC1 -10077
ZNF33B -10074
GATA3 -10071
NFYB -10059
LEF1 -10027
ZNF420 -10020
PMAIP1 -9993
WWP1 -9985
LRPPRC -9966
ZC3H8 -9937
POLR1E -9921
RGCC -9908
CAMK2D -9907
RAD1 -9896

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RORC -10162.0
TCF7 -10143.0
CAMK4 -10131.0
NPM1 -10121.0
KIT -10114.0
GLS -10099.0
NDC1 -10077.0
ZNF33B -10074.0
GATA3 -10071.0
NFYB -10059.0
LEF1 -10027.0
ZNF420 -10020.0
PMAIP1 -9993.0
WWP1 -9985.0
LRPPRC -9966.0
ZC3H8 -9937.0
POLR1E -9921.0
RGCC -9908.0
CAMK2D -9907.0
RAD1 -9896.0
ZNF530 -9862.0
ING5 -9861.0
PRKRA -9857.0
ZNF136 -9839.0
ANAPC1 -9829.0
NR3C2 -9803.0
RPA1 -9799.0
ZNF287 -9796.0
ZNF549 -9781.0
SUPT16H -9777.0
THOC3 -9772.0
ZNF551 -9768.0
HSPD1 -9754.0
DYRK2 -9741.0
PLD6 -9733.0
FOXO1 -9731.0
MYBBP1A -9730.0
NUP35 -9726.0
RPS27A -9723.0
ZIK1 -9720.0
FBXO32 -9702.0
POLR3H -9693.0
ZNF302 -9688.0
RRN3 -9673.0
NUP88 -9668.0
MLLT3 -9657.0
ZNF566 -9650.0
NCBP2 -9631.0
DNMT1 -9624.0
ZNF208 -9592.0
SEH1L -9574.0
ZNF337 -9551.0
RUNX2 -9531.0
NR1D2 -9530.0
ZNF711 -9525.0
ZNF485 -9524.0
WRN -9501.0
ZNF286A -9480.0
SUV39H1 -9457.0
STAT1 -9448.0
TFAM -9446.0
SSRP1 -9439.0
ZNF138 -9435.0
PRKCQ -9424.0
CUL1 -9420.0
NR2C2AP -9415.0
RFC3 -9405.0
ZNF202 -9404.0
TNFRSF18 -9397.0
ZNF473 -9381.0
PERP -9367.0
TFB2M -9362.0
MYC -9357.0
RBL2 -9335.0
ZNF681 -9332.0
ZNF517 -9328.0
FANCD2 -9324.0
ZNF548 -9316.0
ZNF30 -9308.0
ZNF599 -9307.0
SRSF5 -9275.0
ZNF567 -9273.0
GAMT -9258.0
ZFP28 -9238.0
RPA3 -9220.0
NR1D1 -9199.0
ZNF14 -9195.0
RORA -9193.0
ZNF354C -9174.0
TP53 -9170.0
POLR1C -9141.0
CDK4 -9130.0
ZNF74 -9105.0
ZNF544 -9096.0
PCGF5 -9089.0
COX11 -9087.0
LSM11 -9085.0
WWOX -9080.0
GTF3A -9078.0
KAT2A -9063.0
ZNF331 -9055.0
ZNF696 -9045.0
POLR3D -9004.0
SRSF11 -9002.0
ZNF354B -8996.0
CCND2 -8971.0
SCMH1 -8966.0
ZNF248 -8934.0
RFC4 -8897.0
CNOT7 -8894.0
CENPJ -8890.0
E2F6 -8869.0
ZNF583 -8867.0
ZNF540 -8856.0
AKT3 -8810.0
ZNF554 -8803.0
POLR1B -8779.0
PLXNA4 -8763.0
TAF4B -8747.0
ZNF432 -8729.0
TGIF2 -8725.0
ZNF563 -8723.0
HDAC9 -8695.0
SNRPF -8687.0
CTLA4 -8684.0
ZNF559 -8682.0
CDC23 -8677.0
TWISTNB -8662.0
PHF1 -8654.0
GLI3 -8649.0
POLR3E -8594.0
ZFP1 -8589.0
PHC1 -8578.0
SRSF6 -8576.0
SNRPE -8564.0
ZNF431 -8542.0
GTF2H3 -8537.0
MED10 -8535.0
DGCR8 -8517.0
ZNF675 -8514.0
NFATC2 -8513.0
ZNF112 -8507.0
PSMB9 -8503.0
ZNF419 -8501.0
RAD17 -8493.0
RAN -8475.0
ZNF43 -8456.0
JMY -8442.0
ZNF263 -8441.0
ZNF671 -8440.0
EPC1 -8428.0
TNKS1BP1 -8421.0
ZNF664 -8410.0
YEATS4 -8405.0
TFDP2 -8396.0
ZNF212 -8395.0
PARP1 -8391.0
PTPN4 -8389.0
PRMT1 -8388.0
ZNF568 -8387.0
RBBP7 -8382.0
NUP43 -8368.0
ZNF773 -8360.0
NUP160 -8357.0
L3MBTL2 -8356.0
BMI1 -8355.0
CNOT6L -8322.0
GPAM -8319.0
POLRMT -8313.0
ZNF529 -8312.0
ZNF211 -8310.0
NOP2 -8307.0
FANCI -8301.0
NUP107 -8285.0
ZNF749 -8279.0
ZNF253 -8261.0
UBTF -8247.0
KRBOX4 -8221.0
ZNF184 -8219.0
GTF2H1 -8203.0
SSB -8196.0
DLL1 -8167.0
PHAX -8164.0
XPO5 -8113.0
TET1 -8108.0
ZNF430 -8107.0
ZNF721 -8104.0
ZNF75A -8090.0
TAF1A -8068.0
TAF9B -8058.0
TAF1D -8048.0
RNPS1 -8030.0
ZNF461 -8022.0
ZNF180 -8011.0
GLS2 -8010.0
ATM -7980.0
ZNF383 -7970.0
ZNF740 -7969.0
ICE2 -7963.0
NUP188 -7953.0
THOC1 -7949.0
ZNF793 -7943.0
ZNF235 -7939.0
TP53RK -7907.0
PPARD -7903.0
ZNF266 -7894.0
ZNF550 -7888.0
ZNF570 -7883.0
SMAD3 -7868.0
ZNF682 -7849.0
ZNF761 -7840.0
CASP6 -7832.0
ZNF446 -7827.0
ZNF416 -7817.0
ZNF300 -7805.0
MEAF6 -7803.0
NUDT21 -7791.0
PSME1 -7778.0
ESR2 -7755.0
ZNF23 -7752.0
ZNF571 -7750.0
POLR3F -7749.0
SIN3A -7740.0
IGFBP3 -7733.0
ZNF678 -7727.0
PIWIL2 -7721.0
ZNF519 -7686.0
TRIM28 -7684.0
IL2RA -7681.0
SMYD2 -7670.0
ITGA4 -7628.0
COX20 -7626.0
PCBP4 -7623.0
PRMT6 -7588.0
COX16 -7578.0
ZNF439 -7576.0
RFC5 -7574.0
RNMT -7569.0
ZNF582 -7563.0
SIRT1 -7544.0
ZNF480 -7534.0
NUP205 -7516.0
ANAPC5 -7485.0
ZNF726 -7482.0
PSMA5 -7476.0
ZNF101 -7475.0
PPP1R13B -7472.0
ZNF792 -7466.0
RAD9A -7462.0
ZFP37 -7456.0
BRIP1 -7428.0
ZNF528 -7422.0
ZSCAN25 -7416.0
ACTL6A -7372.0
BCL2L14 -7358.0
ANAPC16 -7346.0
PSME2 -7327.0
KRBA1 -7316.0
TNRC6C -7302.0
ZNF514 -7289.0
SF3B1 -7276.0
CSTF1 -7266.0
ZNF727 -7257.0
NR2C1 -7255.0
ZNF226 -7240.0
FASLG -7230.0
SRSF7 -7229.0
ZFP2 -7226.0
MDC1 -7222.0
ZNF483 -7220.0
ZNF649 -7212.0
POLR3G -7146.0
MTA3 -7142.0
NUP54 -7131.0
MSH2 -7130.0
MAML2 -7122.0
ZNF257 -7118.0
PCNA -7101.0
RBL1 -7071.0
NUP155 -7061.0
CD3EAP -7055.0
ZNF141 -7054.0
ZNF597 -7046.0
ZNF343 -7036.0
RABGGTB -7020.0
ZNF737 -6994.0
ZNF662 -6969.0
TDRKH -6945.0
CCNC -6937.0
TGIF1 -6918.0
ZNF706 -6913.0
TDRD6 -6904.0
ZNF10 -6889.0
HDAC2 -6871.0
ZNF140 -6857.0
POLR2D -6856.0
ZNF157 -6825.0
EED -6816.0
GTF3C4 -6810.0
ZNF707 -6802.0
ZNF614 -6794.0
PRR5 -6787.0
ZNF3 -6744.0
RUNX3 -6737.0
MAGOHB -6726.0
ZNF616 -6716.0
MED6 -6714.0
E2F5 -6685.0
TDRD12 -6674.0
MRE11 -6668.0
FYTTD1 -6647.0
CBX5 -6643.0
ZNF470 -6614.0
ZNF26 -6613.0
KMT2A -6588.0
ZNF708 -6581.0
ZNF736 -6571.0
RHNO1 -6539.0
CHD3 -6523.0
ERCC6 -6508.0
UXT -6504.0
GATA2 -6470.0
CCNG1 -6462.0
NUP93 -6458.0
TCEA1 -6441.0
PSMA3 -6433.0
ZNF17 -6429.0
ZNF606 -6404.0
SRC -6396.0
ZFP69 -6391.0
ZNF680 -6386.0
ZNF677 -6358.0
SNRPD3 -6352.0
MNAT1 -6327.0
DNA2 -6307.0
SKP1 -6297.0
ZFP90 -6295.0
ZKSCAN8 -6292.0
AEBP2 -6285.0
ZNF771 -6283.0
ZNF799 -6276.0
SGK1 -6264.0
MAPKAPK5 -6258.0
ZNF738 -6246.0
ZNF506 -6235.0
POLR2H -6200.0
ZNF135 -6198.0
PIP4K2B -6196.0
SRSF2 -6188.0
ZNF584 -6175.0
CHEK1 -6143.0
ERBB2 -6142.0
PIDD1 -6109.0
BTG1 -6108.0
ZNF12 -6071.0
ZNF274 -6041.0
TRIAP1 -6036.0
MEF2C -6025.0
MYBL1 -6024.0
ZNF510 -6017.0
ZNF415 -6008.0
ZNF175 -5991.0
DROSHA -5976.0
ZNF154 -5972.0
ZNF317 -5967.0
ZNF496 -5965.0
BRD1 -5958.0
MOV10 -5956.0
MBD3 -5950.0
ZNF772 -5933.0
SETD1A -5910.0
PVALB -5879.0
TAF5 -5865.0
SMURF2 -5858.0
ZNF790 -5845.0
UPF3B -5843.0
ZNF782 -5838.0
ZNF285 -5804.0
INTS5 -5803.0
MGA -5799.0
ZNF234 -5788.0
TBP -5776.0
PPP1R13L -5769.0
ZFP30 -5763.0
ZNF777 -5753.0
ZNF224 -5735.0
H2BC9 -5728.0
RAD51D -5721.0
SRRT -5701.0
SCO1 -5653.0
SESN1 -5650.0
MTF2 -5639.0
ZNF223 -5631.0
ZNF786 -5630.0
ZNF600 -5624.0
RBBP4 -5599.0
H2AZ2 -5576.0
MAF -5558.0
SRSF3 -5550.0
ZNF596 -5548.0
PRKAB2 -5520.0
TSN -5497.0
TAF3 -5461.0
ZNF577 -5437.0
FOXP3 -5412.0
BTG2 -5374.0
ZNF273 -5371.0
MEN1 -5364.0
SMARCD1 -5357.0
NUP133 -5346.0
ATR -5340.0
SUZ12 -5320.0
COX14 -5300.0
E2F7 -5283.0
RICTOR -5264.0
COX6C -5236.0
PHF20 -5199.0
PPP2R5C -5198.0
TCF3 -5184.0
ZNF92 -5177.0
MT-CO3 -5157.0
BLM -5151.0
YY1 -5142.0
TAF9 -5099.0
TRPC3 -5092.0
ZNF33A -5085.0
BRF2 -5077.0
ZNF133 -5063.0
TXNIP -5058.0
ZNF417 -5015.0
AUTS2 -4988.0
ZNF569 -4986.0
SESN3 -4984.0
ZNF607 -4976.0
MAMLD1 -4969.0
ZNF493 -4959.0
ZNF709 -4926.0
ZNF692 -4918.0
POLR2K -4907.0
ZSCAN32 -4901.0
SMARCA5 -4893.0
ZNF860 -4892.0
COX19 -4881.0
ZNF227 -4873.0
NELFCD -4863.0
TP73 -4859.0
TAF15 -4857.0
ZNF658 -4856.0
ZNF605 -4845.0
CDK6 -4840.0
LDB1 -4826.0
ZNF573 -4817.0
RPA2 -4811.0
MTERF1 -4778.0
ZNF334 -4743.0
ZNF620 -4741.0
ICE1 -4727.0
COX7C -4688.0
MAGOH -4678.0
TTC5 -4664.0
ZNF785 -4652.0
SNAPC1 -4648.0
MAPK11 -4641.0
AIFM2 -4640.0
YWHAQ -4624.0
ZNF626 -4612.0
SETD9 -4610.0
ZNF2 -4566.0
ZNF433 -4558.0
PSMC5 -4553.0
ZNF268 -4552.0
VENTX -4549.0
TARBP2 -4537.0
ATAD2 -4527.0
ZFP14 -4515.0
ZNF767P -4494.0
CDC7 -4493.0
MYB -4488.0
ZFPM1 -4486.0
INTS4 -4485.0
POLR3C -4461.0
CYCS -4456.0
MTA1 -4442.0
ZNF233 -4440.0
ZNF585B -4432.0
ZNF500 -4424.0
ZNF492 -4394.0
SMARCC1 -4387.0
COX18 -4373.0
BLK -4300.0
YAF2 -4258.0
THRB -4237.0
ZNF543 -4233.0
ZNF70 -4218.0
ZNF441 -4195.0
SNRPB -4187.0
ZNF75D -4153.0
POLR1A -4152.0
PMS2 -4151.0
ZNF440 -4147.0
ZNF37A -4117.0
CDC16 -4089.0
PSMB10 -4050.0
NUP42 -4045.0
PRDX2 -4039.0
CPSF4 -4025.0
HSP90AA1 -4016.0
ZNF425 -4008.0
ZNF625 -3979.0
CREB1 -3977.0
PRDM1 -3968.0
SKI -3963.0
ZNF484 -3957.0
NUP210 -3949.0
POLR2I -3929.0
ZNF45 -3920.0
ZNF688 -3901.0
GTF3C2 -3893.0
CCNT1 -3880.0
ZNF621 -3874.0
ANAPC2 -3830.0
SCO2 -3829.0
CCND1 -3813.0
RRP8 -3795.0
CTSV -3775.0
EZH2 -3766.0
H19 -3763.0
DDX39A -3754.0
TPR -3744.0
NR2F6 -3738.0
RING1 -3707.0
CCNE1 -3688.0
ZNF703 -3683.0
RARG -3682.0
SUPT5H -3672.0
ZNF382 -3661.0
MECP2 -3660.0
SMAD4 -3639.0
PAX5 -3632.0
CDK2 -3614.0
PSMB1 -3610.0
ATRIP -3603.0
BDP1 -3597.0
ZNF19 -3587.0
RAD51 -3583.0
ZNF610 -3580.0
UBA52 -3490.0
ZNF324 -3489.0
ZNF250 -3486.0
ZNF521 -3453.0
TTF1 -3437.0
NUP85 -3427.0
ZNF670 -3401.0
DEK -3397.0
POLR2B -3384.0
AAAS -3332.0
ZNF546 -3301.0
TACO1 -3299.0
ZNF486 -3296.0
ZNF714 -3288.0
ZNF564 -3260.0
RAD50 -3254.0
ZNF324B -3252.0
ZNF689 -3229.0
ZNF595 -3227.0
SMARCE1 -3212.0
CDKN1B -3127.0
NFIX -3067.0
ESR1 -3021.0
SOCS4 -2988.0
AXIN1 -2986.0
UBE2E1 -2985.0
MED27 -2978.0
CBX2 -2958.0
ZNF557 -2919.0
EXO1 -2916.0
RPAP2 -2876.0
TAF1B -2851.0
YES1 -2846.0
MED30 -2845.0
PSMA2 -2823.0
NELFA -2822.0
SLBP -2817.0
TNFRSF10A -2801.0
ZNF561 -2797.0
ZNF418 -2796.0
RPRD2 -2788.0
ZNRD1 -2771.0
POLR3B -2765.0
PSMA4 -2764.0
ZNF77 -2710.0
ANAPC4 -2692.0
STUB1 -2688.0
SMARCB1 -2683.0
CNOT10 -2678.0
NR4A1 -2672.0
EHMT2 -2671.0
POLR3GL -2666.0
RRAGB -2658.0
MED17 -2648.0
HENMT1 -2630.0
THOC2 -2624.0
CDK1 -2593.0
ZNF558 -2569.0
NFIB -2552.0
CNOT2 -2544.0
THOC6 -2527.0
MT-CO2 -2523.0
PSMD10 -2515.0
MED31 -2514.0
RRM2 -2442.0
NUP62 -2410.0
WDR61 -2390.0
PHC3 -2377.0
UBE2I -2356.0
NUAK1 -2339.0
SIRT3 -2325.0
NUP37 -2275.0
MED4 -2264.0
WDR5 -2237.0
ZNF791 -2198.0
ALYREF -2176.0
SRRM1 -2172.0
U2AF1L4 -2154.0
DAXX -2153.0
PF4 -2122.0
ZNF264 -2113.0
INTS9 -2090.0
ZNF585A -2053.0
DNMT3A -2045.0
POLR3K -2014.0
THRA -2010.0
ZC3H11A -2004.0
ZNF169 -1961.0
NR4A3 -1943.0
ZNF160 -1941.0
BRD7 -1932.0
PRKAG2 -1916.0
ZNF436 -1909.0
SKP2 -1895.0
CLDN5 -1869.0
FIP1L1 -1860.0
ANAPC10 -1816.0
ZNF724 -1814.0
PABPN1 -1789.0
PPARGC1A -1762.0
CDC26 -1744.0
ZNF720 -1737.0
ING2 -1723.0
NR2C2 -1712.0
POM121C -1710.0
GTF2H5 -1698.0
ZNF717 -1691.0
BRF1 -1688.0
ZNF684 -1667.0
ZNF624 -1616.0
BBC3 -1611.0
ZNF665 -1605.0
ZNF221 -1593.0
SRSF1 -1573.0
ZNF41 -1570.0
GTF3C3 -1554.0
L3MBTL1 -1539.0
ZNF676 -1527.0
RBM14 -1512.0
RBM8A -1499.0
NR4A2 -1447.0
FBXW7 -1315.0
ZNF100 -1250.0
CALM1 -1245.0
GTF2A1 -1202.0
DDX21 -1198.0
ZNF565 -1174.0
ZNF34 -1172.0
MYBL2 -1171.0
RANBP2 -1141.0
RPTOR -1137.0
ZNF547 -1122.0
ZNF667 -1090.0
PCGF6 -1085.0
RBBP5 -1075.0
ZNF426 -1066.0
MLST8 -1064.0
DDB2 -1024.0
NOC2L -998.0
ZNF99 -982.0
MED1 -971.0
MYO1C -962.0
DDX39B -960.0
IFNG -958.0
TMEM219 -957.0
NCBP1 -942.0
ZNF197 -922.0
MED15 -911.0
CSTF2T -904.0
TFAP2E -902.0
CHEK2 -865.0
SNAPC5 -861.0
CSTF2 -856.0
ZNF195 -841.0
PML -815.0
GTF2H4 -803.0
LEO1 -778.0
ZNF71 -753.0
ATXN3 -673.0
ZNF589 -659.0
ATF2 -657.0
ZNF713 -656.0
SARNP -641.0
CCNT2 -632.0
ZNF700 -598.0
CPSF1 -561.0
POLR2C -494.0
WDR33 -474.0
TRIM33 -473.0
FANCC -455.0
MT-CO1 -454.0
PSMB8 -438.0
ZNF615 -407.0
DPY30 -319.0
TAF1 -304.0
TJP1 -300.0
COX4I1 -286.0
RMI2 -282.0
ZNF770 -273.0
ELF1 -271.0
STK11 -238.0
BRD2 -209.0
RELA -204.0
ZNF627 -194.0
PCGF2 -177.0
SNAPC4 -160.0
MAX -145.0
POM121 -142.0
RNF34 -115.0
PPARGC1B -31.0
BAZ1B -4.0
INTS10 37.0
TAF1C 45.0
CDKN2A 48.0
SMAD7 52.0
ARID4B 62.0
PPP2R1B 89.0
TAF11 95.0
BGLAP 197.0
HDAC6 243.0
RNF2 248.0
NUP153 254.0
CDC27 283.0
CHD4 290.0
H2BU1 298.0
TNRC6B 301.0
OCLN 304.0
TNRC6A 318.0
THOC7 348.0
SLU7 354.0
PIP4K2A 379.0
TOPBP1 397.0
ZNF350 404.0
OPRM1 433.0
U2AF2 483.0
ANAPC7 498.0
GTF3C5 501.0
CBFB 503.0
ZNF155 509.0
KMT2E 515.0
ZNF655 517.0
PLK2 549.0
SNRPG 560.0
PIN1 577.0
ARID1B 588.0
PSMC4 605.0
ZNF222 626.0
MED13 630.0
PSMB4 642.0
HDAC1 650.0
ZNF699 661.0
ZNF442 703.0
ZNF764 733.0
CCNB1 735.0
ZNF747 780.0
TAF6 791.0
PIWIL4 814.0
SAP30BP 840.0
ZNF398 863.0
GAD2 875.0
E2F8 895.0
PSMC3 916.0
PSMD14 941.0
NR1H3 954.0
CITED4 960.0
ZNF562 990.0
CASP10 1005.0
NR3C1 1021.0
UBB 1026.0
ZNF189 1034.0
KLF4 1084.0
CHM 1115.0
PIP4K2C 1118.0
ZNF716 1137.0
TSNAX 1151.0
GTF2B 1157.0
SYMPK 1165.0
MED7 1178.0
MED24 1185.0
MLH1 1189.0
CHTOP 1241.0
BRPF3 1249.0
FAS 1260.0
ZNF200 1270.0
ZNF124 1333.0
MDM4 1356.0
CDK5R1 1363.0
PRELID3A 1364.0
ZNF619 1399.0
TSC1 1403.0
ZNF443 1414.0
CNOT11 1459.0
TAF4 1471.0
NBN 1482.0
EIF4A3 1507.0
SAP18 1549.0
PRMT5 1582.0
ZNF641 1585.0
RPRD1A 1598.0
CTR9 1610.0
ZNF776 1623.0
NABP2 1635.0
ZNF750 1680.0
POLR1D 1703.0
ZNF778 1729.0
ZKSCAN4 1738.0
RRAGC 1745.0
INTS7 1753.0
PSMB2 1760.0
MTOR 1777.0
ZKSCAN3 1789.0
NELFB 1812.0
PSME4 1818.0
SFN 1840.0
SMARCA2 1856.0
CCNA2 1863.0
MED23 1915.0
MYL9 1931.0
AURKB 1985.0
GTF3C6 1991.0
POLR2L 2016.0
CASP2 2017.0
ZNF660 2023.0
CCNH 2048.0
KAT2B 2054.0
SIN3B 2071.0
PSMD7 2084.0
RABGGTA 2092.0
BRPF1 2098.0
CDK13 2118.0
GTF2A2 2140.0
ZNF691 2191.0
POU2F2 2197.0
FKBP6 2224.0
CAV1 2229.0
AGRP 2238.0
SREBF1 2292.0
ZNF658B 2299.0
CBX3 2333.0
ZNF669 2359.0
TCF12 2381.0
PRKAA1 2409.0
HDAC10 2431.0
GTF2E1 2433.0
APOE 2448.0
H2BC15 2474.0
CAMK2G 2528.0
GPS2 2541.0
AGO3 2552.0
ZNF587 2582.0
CBX8 2624.0
NUP50 2638.0
ZNF429 2657.0
HIVEP3 2666.0
ZNF79 2726.0
ZNF556 2729.0
CNOT8 2767.0
FOS 2787.0
RXRB 2848.0
NFKB1 2860.0
MTA2 2877.0
CASP1 2896.0
BANP 2945.0
SUDS3 3040.0
CNOT4 3043.0
INTS12 3065.0
ZNF25 3085.0
RRM2B 3109.0
TAF2 3110.0
PSMA1 3111.0
JUN 3122.0
TAL1 3132.0
EHMT1 3155.0
BCDIN3D 3166.0
COX5A 3171.0
TAF7 3179.0
PCF11 3209.0
POLR3A 3224.0
SUPT4H1 3268.0
ZNF668 3291.0
UHRF1 3301.0
GTF2H2 3309.0
ZNF320 3311.0
GCK 3322.0
SNW1 3347.0
SURF1 3355.0
GPX2 3367.0
HDAC5 3369.0
ERCC3 3424.0
RFFL 3429.0
INTS2 3437.0
SEM1 3454.0
CRADD 3517.0
UBE2C 3555.0
KAT5 3557.0
CCNE2 3568.0
ZKSCAN1 3585.0
ARID2 3609.0
CSTF3 3626.0
ZNF555 3636.0
MOBP 3646.0
ITGAL 3647.0
ZNF611 3658.0
DNMT3B 3720.0
ELOA 3736.0
PSMD13 3766.0
TCF7L1 3775.0
ZNF394 3785.0
PRDX1 3802.0
POMC 3862.0
ANAPC11 3904.0
ZNF347 3913.0
NPPA 3921.0
SNAPC3 3923.0
RTF1 3926.0
RBX1 3957.0
FZR1 3967.0
COX7A2L 3979.0
RNGTT 4041.0
SUMO1 4061.0
INTS8 4109.0
GP1BA 4136.0
ZNF215 4137.0
DDIT4 4138.0
CDK7 4155.0
MED16 4162.0
POLR2G 4175.0
ZNF701 4187.0
ZNF839 4197.0
HUS1 4236.0
CNOT1 4249.0
BARD1 4253.0
POLR2F 4256.0
PSMF1 4259.0
PSMD3 4297.0
TSC2 4311.0
CDK8 4340.0
H2AZ1 4378.0
TPX2 4403.0
NDUFA4 4421.0
RHEB 4425.0
COX7B 4513.0
BIRC5 4541.0
PSMC2 4543.0
KAT6A 4584.0
MAPKAP1 4588.0
THBS1 4645.0
ZNF718 4650.0
BNIP3L 4710.0
YWHAB 4721.0
INTS6 4729.0
TDG 4742.0
UBE2S 4773.0
AFF4 4808.0
PSMC1 4827.0
ELL2 4850.0
TBL1XR1 4852.0
ZNF471 4855.0
PPARA 4862.0
ZNF586 4863.0
ZNF20 4882.0
DHX38 4887.0
ZFP69B 4901.0
ZNF490 4930.0
PSMC6 4959.0
ZNF205 4960.0
ZNF385A 5003.0
SERPINE1 5005.0
RAE1 5007.0
COX5B 5048.0
SSU72 5062.0
GPRIN1 5069.0
PAF1 5073.0
CDC40 5078.0
EAF2 5079.0
POLR2E 5109.0
ZNF775 5111.0
PHF19 5188.0
PPP2R1A 5189.0
YWHAZ 5202.0
PSMA6 5209.0
E2F4 5213.0
CBX6 5259.0
CTSK 5320.0
PAPOLA 5344.0
LAMTOR3 5383.0
RPRD1B 5395.0
KCTD6 5411.0
SUPT6H 5421.0
HDAC3 5437.0
H2AC6 5440.0
BAX 5446.0
HDAC11 5471.0
RFC2 5478.0
SLC38A9 5485.0
TEAD2 5487.0
ELL3 5492.0
AKT2 5502.0
TGFB1 5504.0
ZNF460 5515.0
CDKN1A 5537.0
CLP1 5591.0
POLR2J 5598.0
MED14 5610.0
CDK9 5620.0
VEGFA 5648.0
PSMD8 5687.0
KCTD1 5799.0
CDC25C 5800.0
ZNF613 5823.0
ZNF354A 5856.0
SMARCC2 5869.0
NUP98 5874.0
CSNK2B 5876.0
COX6A1 5884.0
CPSF7 5894.0
WWTR1 5902.0
CDK12 5907.0
PBRM1 5917.0
NR1I3 5969.0
GATAD2B 5985.0
TAF8 5995.0
LAMTOR4 6002.0
MDM2 6043.0
AGO2 6087.0
H2BC11 6121.0
ABL1 6127.0
KRAS 6132.0
ZNF143 6133.0
UBC 6135.0
ZNF697 6137.0
ZNF702P 6149.0
SAP30L 6155.0
H2BC17 6188.0
GTF3C1 6207.0
CDC73 6229.0
HDAC8 6235.0
GTF2F2 6257.0
USP7 6259.0
SMAD2 6291.0
USP9X 6344.0
U2AF1 6360.0
RBBP8 6377.0
KMT2C 6410.0
INTS1 6441.0
LSM10 6472.0
DDIT3 6480.0
SMURF1 6481.0
AKT1 6498.0
ZFHX3 6518.0
PTPN11 6524.0
MED26 6537.0
TIGAR 6589.0
RAD9B 6597.0
RYBP 6609.0
ERCC2 6621.0
IPO8 6633.0
AR 6643.0
NFYA 6667.0
AURKA 6693.0
NELFE 6710.0
ZNF774 6717.0
GTF2F1 6738.0
ITCH 6755.0
H2BC5 6759.0
PPP2CA 6806.0
E2F1 6818.0
PSMD12 6820.0
SKIL 6851.0
TP53INP1 6853.0
PLK3 6889.0
GATAD2A 6890.0
ZKSCAN7 6896.0
TNFRSF10D 6912.0
ELOC 6974.0
GTF2E2 6979.0
CCNA1 7002.0
RNF111 7005.0
BRCA1 7032.0
G6PC 7036.0
SRSF4 7085.0
PRELID1 7109.0
GPI 7117.0
GSK3B 7147.0
PRKAB1 7148.0
CPSF2 7191.0
EAF1 7231.0
CRCP 7239.0
CNOT6 7242.0
JUNB 7257.0
SOD2 7284.0
PSMD6 7307.0
CPSF3 7310.0
CSNK2A2 7341.0
ITGA2B 7387.0
HDAC7 7388.0
PSMB6 7399.0
NRBP1 7428.0
ELOB 7435.0
CBX4 7438.0
PPP2CB 7451.0
ELF2 7487.0
ABCA6 7495.0
PLAGL1 7496.0
SEC13 7506.0
HES1 7535.0
BID 7544.0
PPM1D 7552.0
SETD1B 7555.0
SNAPC2 7561.0
MBD2 7618.0
PSMD5 7646.0
KCTD15 7676.0
SMARCD3 7698.0
MED12 7718.0
TBL1X 7764.0
PSMD11 7775.0
PRKAG1 7805.0
PSMA7 7840.0
POU2F1 7849.0
POLR2A 7852.0
ZKSCAN5 7864.0
SMARCA4 7879.0
KMT2B 7908.0
IRAK1 7970.0
PSMB3 8005.0
LAMTOR2 8006.0
COX6B1 8031.0
CCNK 8038.0
ZNF552 8044.0
COX8A 8092.0
MED25 8136.0
PSMD2 8139.0
CREBBP 8143.0
NCOR1 8153.0
PSMD1 8184.0
ELL 8187.0
ZNF333 8189.0
ZNF267 8220.0
JAG1 8240.0
RRAGD 8243.0
ZNF18 8255.0
BAZ2A 8261.0
PSMB5 8265.0
ANAPC15 8323.0
SMARCD2 8363.0
NOTCH2 8400.0
NFIA 8405.0
PSMB7 8460.0
CITED2 8503.0
HIPK1 8544.0
CNOT3 8550.0
PRKCB 8577.0
UBE2D3 8641.0
MED8 8643.0
ZNF468 8676.0
TFDP1 8682.0
PDPK1 8710.0
SRSF9 8713.0
PSME3 8716.0
TAF13 8718.0
IWS1 8736.0
ZNF282 8738.0
MED20 8757.0
PSMD9 8766.0
AGO1 8810.0
APAF1 8822.0
LBR 8834.0
TAF12 8850.0
ASH2L 8855.0
KMT2D 8863.0
LAMTOR5 8889.0
H2AC20 8893.0
ZNF28 8904.0
PPM1A 8912.0
H2BC4 8925.0
H3C15 8929.5
CDKN2B 8931.0
TNFRSF10B 8944.0
ZNF230 8954.0
YWHAE 8971.0
H3-3A 8985.0
NR6A1 9008.0
RMI1 9032.0
RRAGA 9038.0
CSNK2A1 9040.0
NRBF2 9084.0
SAP130 9086.0
NEDD4L 9088.0
TP53BP2 9121.0
TNFRSF10C 9127.0
BCL2L11 9144.0
LGALS3 9180.0
ESRRA 9192.0
FOXO4 9205.0
JARID2 9206.0
ZNF445 9223.0
SATB2 9256.0
LAMTOR1 9265.0
PRDX5 9267.0
TXN 9268.0
H2BC12 9280.0
UBE2D1 9286.0
CTDP1 9289.0
CCNG2 9366.0
SAP30 9383.0
KDM5B 9406.0
TAF10 9419.0
NOTCH1 9499.0
NR1H2 9521.0
GATA1 9542.0
PTEN 9545.0
ARID1A 9567.0
NUP58 9577.0
TET2 9589.0
CASC3 9610.0
CSF1R 9627.0
ZNF213 9638.0
CTNNB1 9670.0
HTT 9679.0
TOP3A 9684.0
H2BC21 9690.0
SP1 9699.0
MAPK3 9750.0
SESN2 9768.0
LMO2 9776.0
STEAP3 9786.0
EP300 9789.0
TET3 9792.0
FOXO3 9800.0
INTS3 9830.0
RB1 9839.0
ITGA5 9848.0
TXNRD1 9890.0
NDRG1 10027.0
MAML1 10046.0
YWHAH 10050.0
DICER1 10051.0
HIPK2 10064.0
RXRA 10073.0
DLX6 10075.0
ARID3A 10084.0
PSMD4 10088.0
CAT 10103.0
NUP214 10131.0
RBPJ 10176.0
POLDIP3 10182.0
ZNF746 10212.0
CTSL 10288.0
NOTCH4 10293.0
CARM1 10313.0
THOC5 10316.0
MLLT1 10332.0
TWIST2 10353.0
YWHAG 10453.0
KMT5A 10459.0
NFYC 10461.0
CCND3 10476.0
RUNX1 10531.0
PINK1 10533.0
AGO4 10537.0
NABP1 10575.0
ACTB 10606.0
ZNF710 10617.0
PTPN1 10623.0
CDK5 10628.0
MAML3 10651.0
NFIC 10664.0
SLC2A3 10714.0
RETN 10732.0
TCF7L2 10773.0
RARA 10808.0
SMAD6 10809.0
SOCS3 10826.0
HDAC4 10884.0
G6PD 10948.0
MAP2K6 10958.0
FKBP5 10974.0
TGFA 10983.0
GSR 11051.0
GADD45A 11089.0
MAPK14 11115.0
CEBPB 11136.0
PHC2 11145.0
MAPK1 11193.0
RNU1-1 11197.5
NCOR2 11217.0
SPI1 11223.0
NLRC4 11239.0
NFE2 11293.0
BCL6 11324.0
TDRD9 11360.0
PRKACA 11363.0
VDR 11370.0
CR1 11401.0
SMAD1 11403.0
NOTCH3 11420.0
TP53I3 11439.0
H2AJ 11447.0
PPARG 11451.0


Translation initiation complex formation

Translation initiation complex formation
1267
set Translation initiation complex formation
setSize 58
pANOVA 1.23e-14
s.dist -0.585
p.adjustANOVA 4.8e-13



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS3A -9834
RPS27A -9723
RPS6 -9699
RPS25 -9664
EIF4A2 -9593
RPS2 -9591
EIF3B -9526
RPS20 -9413
RPS23 -9387
RPS3 -9298
RPS12 -9270
RPS27 -9175
RPS7 -9165
EIF3E -9049
RPS5 -9042
RPS15A -8883
RPS8 -8861
RPS13 -8724
RPS4X -8648
RPS29 -8637

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS3A -9834
RPS27A -9723
RPS6 -9699
RPS25 -9664
EIF4A2 -9593
RPS2 -9591
EIF3B -9526
RPS20 -9413
RPS23 -9387
RPS3 -9298
RPS12 -9270
RPS27 -9175
RPS7 -9165
EIF3E -9049
RPS5 -9042
RPS15A -8883
RPS8 -8861
RPS13 -8724
RPS4X -8648
RPS29 -8637
RPS16 -8579
RPS14 -8541
RPS10 -8494
EIF1AX -8383
RPS21 -8330
RPS18 -8321
RPS17 -8281
EIF3L -8255
EIF4B -8190
RPS28 -8083
RPS11 -7975
RPS19 -7806
EIF3H -7091
RPS24 -6818
EIF3M -6817
RPS15 -6703
RPSA -6629
EIF3J -6448
EIF3F -5200
EIF3D -5158
EIF3C -4716
FAU -3618
PABPC1 -2991
EIF3G -2746
EIF3I -2580
EIF3K -2369
EIF2S1 -1649
EIF3A -1276
RPS26 -1154
RPS27L -496
RPS4Y1 331
EIF2S2 554
EIF4E 1661
RPS9 1841
EIF2S3 2500
EIF4A1 5541
EIF4H 7768
EIF4G1 10506


Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S

Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
49
set Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
setSize 59
pANOVA 2.93e-14
s.dist -0.572
p.adjustANOVA 1.11e-12



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS3A -9834
RPS27A -9723
RPS6 -9699
RPS25 -9664
EIF4A2 -9593
RPS2 -9591
EIF3B -9526
RPS20 -9413
RPS23 -9387
RPS3 -9298
RPS12 -9270
RPS27 -9175
RPS7 -9165
EIF3E -9049
RPS5 -9042
RPS15A -8883
RPS8 -8861
RPS13 -8724
RPS4X -8648
RPS29 -8637

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS3A -9834
RPS27A -9723
RPS6 -9699
RPS25 -9664
EIF4A2 -9593
RPS2 -9591
EIF3B -9526
RPS20 -9413
RPS23 -9387
RPS3 -9298
RPS12 -9270
RPS27 -9175
RPS7 -9165
EIF3E -9049
RPS5 -9042
RPS15A -8883
RPS8 -8861
RPS13 -8724
RPS4X -8648
RPS29 -8637
RPS16 -8579
RPS14 -8541
RPS10 -8494
EIF1AX -8383
RPS21 -8330
RPS18 -8321
RPS17 -8281
EIF3L -8255
EIF4B -8190
RPS28 -8083
RPS11 -7975
RPS19 -7806
EIF3H -7091
RPS24 -6818
EIF3M -6817
RPS15 -6703
RPSA -6629
EIF3J -6448
EIF3F -5200
EIF3D -5158
EIF3C -4716
FAU -3618
PABPC1 -2991
EIF3G -2746
EIF3I -2580
EIF3K -2369
EIF2S1 -1649
EIF3A -1276
RPS26 -1154
RPS27L -496
RPS4Y1 331
EIF2S2 554
EIF4E 1661
RPS9 1841
EIF2S3 2500
EIF4EBP1 2825
EIF4A1 5541
EIF4H 7768
EIF4G1 10506


Ribosomal scanning and start codon recognition

Ribosomal scanning and start codon recognition
1014
set Ribosomal scanning and start codon recognition
setSize 58
pANOVA 3.26e-14
s.dist -0.576
p.adjustANOVA 1.2e-12



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS3A -9834
RPS27A -9723
RPS6 -9699
RPS25 -9664
EIF4A2 -9593
RPS2 -9591
EIF3B -9526
RPS20 -9413
RPS23 -9387
RPS3 -9298
RPS12 -9270
RPS27 -9175
RPS7 -9165
EIF3E -9049
RPS5 -9042
RPS15A -8883
RPS8 -8861
RPS13 -8724
RPS4X -8648
RPS29 -8637

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS3A -9834
RPS27A -9723
RPS6 -9699
RPS25 -9664
EIF4A2 -9593
RPS2 -9591
EIF3B -9526
RPS20 -9413
RPS23 -9387
RPS3 -9298
RPS12 -9270
RPS27 -9175
RPS7 -9165
EIF3E -9049
RPS5 -9042
RPS15A -8883
RPS8 -8861
RPS13 -8724
RPS4X -8648
RPS29 -8637
RPS16 -8579
RPS14 -8541
RPS10 -8494
EIF1AX -8383
RPS21 -8330
RPS18 -8321
RPS17 -8281
EIF3L -8255
EIF4B -8190
RPS28 -8083
RPS11 -7975
RPS19 -7806
EIF3H -7091
RPS24 -6818
EIF3M -6817
RPS15 -6703
RPSA -6629
EIF3J -6448
EIF3F -5200
EIF3D -5158
EIF3C -4716
FAU -3618
EIF3G -2746
EIF3I -2580
EIF3K -2369
EIF2S1 -1649
EIF3A -1276
RPS26 -1154
RPS27L -496
RPS4Y1 331
EIF2S2 554
EIF4E 1661
RPS9 1841
EIF2S3 2500
EIF5 2937
EIF4A1 5541
EIF4H 7768
EIF4G1 10506


Platelet activation, signaling and aggregation

Platelet activation, signaling and aggregation
827
set Platelet activation, signaling and aggregation
setSize 221
pANOVA 1.64e-13
s.dist 0.288
p.adjustANOVA 5.86e-12



Top enriched genes

Top 20 genes
GeneID Gene Rank
F5 11434
SERPINA1 11407
P2RY1 11378
QSOX1 11369
CD63 11355
STXBP2 11285
TIMP1 11275
FCER1G 11216
MAPK1 11193
GTPBP2 11180
PRKCD 11168
MAPK14 11115
CYB5R1 11052
TOR4A 11002
FERMT3 10998
CD36 10947
APLP2 10928
GNA15 10907
ALDOA 10868
CLU 10812

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
F5 11434
SERPINA1 11407
P2RY1 11378
QSOX1 11369
CD63 11355
STXBP2 11285
TIMP1 11275
FCER1G 11216
MAPK1 11193
GTPBP2 11180
PRKCD 11168
MAPK14 11115
CYB5R1 11052
TOR4A 11002
FERMT3 10998
CD36 10947
APLP2 10928
GNA15 10907
ALDOA 10868
CLU 10812
LYN 10810
GRB2 10733
GNG5 10721
ARRB2 10688
RHOG 10635
RAC1 10624
PTPN1 10623
APBB1IP 10622
PTPN6 10446
HGF 10417
PECAM1 10414
GNB1 10392
CRK 10387
DAGLB 10338
SCCPDH 10298
GNB2 10282
GNAI2 10264
SYK 10256
PLCG2 10244
ACTN4 10230
VAV1 10226
TLN1 10191
GNG10 10071
PIK3R6 10025
LHFPL2 9956
CAP1 9934
GAS6 9901
SRGN 9887
GNAQ 9871
WDR1 9868
ACTN1 9811
PLA2G4A 9803
CFL1 9794
MAPK3 9750
RAF1 9686
SHC1 9541
RHOA 9401
CSK 9400
ANXA5 9269
PIK3CG 9128
PIK3CB 9126
RAPGEF3 9100
CALU 9049
LAMP2 9034
VTI1B 8933
PSAP 8894
PDPK1 8710
ALB 8630
PRKCB 8577
VAV3 8413
PFN1 8397
CLEC1B 8373
GNAI3 8344
CDC42 8342
FLNA 8318
RAC2 8237
DGKG 8235
PRKCE 8190
TUBA4A 8035
F8 8026
RHOB 7921
ITPR2 7716
SYTL4 7697
PIK3R5 7579
CLEC3B 7525
ITGA2B 7387
RAP1A 7335
STXBP3 7210
GNB4 7078
HSPA5 7027
STX4 7026
RAP1B 6962
DGKD 6870
ABHD6 6665
PTPN11 6524
PIK3R2 6511
AKT1 6498
APP 6245
VCL 6193
GP1BB 6153
CD109 6110
ECM1 6098
TTN 6088
TGFB2 6083
CD9 5818
F2RL2 5667
GP9 5664
GP6 5660
VEGFA 5648
VEGFC 5567
TGFB1 5504
SELP 5380
PDGFA 5341
GNA13 5302
EGF 5267
YWHAZ 5202
SERPINE1 5005
PLEK 4699
THBS1 4645
TBXA2R 4539
GNG3 4481
GNG8 4328
PROS1 4191
GP1BA 4136
ARRB1 3956
VWF 3870
LCP2 3759
PHACTR2 3743
F2RL3 3631
MMRN1 3618
TIMP3 3154
GNG2 3124
ITGB3 2944
LY6G6F 2813
F2R 2762
VAV2 2755
PIK3R3 2676
P2RY12 2608
TAGLN2 2525
GNG4 2481
PIK3CA 2133
MPL 2081
ORM1 2075
MGLL 1993
TRPC6 1988
MAGED2 1652
ABCC4 1639
GNGT2 1513
F13A1 1493
BRPF3 1249
TF 1246
ADRA2A 1007
CHID1 786
RAB27B 774
GNAI1 579
ORM2 565
CFD 461
MANF 445
PTK2 388
PLG 218
PCYOX1L -458
GNA12 -817
TMSB4X -850
APOOL -867
SPARC -1002
DGKQ -1073
CALM1 -1245
SERPINF2 -1375
ENDOD1 -1464
A1BG -1468
FN1 -1829
PPBP -1960
PF4 -2122
A2M -2133
DGKZ -2312
DGKH -2353
PRKCA -2408
CTSW -2441
GNA11 -2784
ITIH4 -2921
SOS1 -2983
TMX3 -3613
ITPR1 -3676
GNG11 -3895
TEX264 -4024
DAGLA -4626
NHLRC2 -4700
ABHD12 -4829
GNB5 -4864
TRPC3 -5092
FYN -5211
OLA1 -5737
GNG7 -5880
PRKCZ -6016
GP5 -6093
GNB3 -6125
RASGRP2 -6127
ITPR3 -6139
AAMP -6320
SRC -6396
PPIA -6498
SELENOP -6746
TGFB3 -6903
ITIH3 -7066
CDC37L1 -7116
LGALS3BP -7405
SOD1 -7420
SERPING1 -7610
DGKE -8629
DGKA -8817
PIK3R1 -8831
FAM3C -9260
RASGRP1 -9394
PRKCQ -9424
LAT -9470
VEGFB -9481
LCK -9556
PDGFB -9562
PRKCH -9600
DGKK -9915
HABP4 -10030


Signaling by Receptor Tyrosine Kinases

Signaling by Receptor Tyrosine Kinases
1129
set Signaling by Receptor Tyrosine Kinases
setSize 414
pANOVA 8.43e-13
s.dist 0.205
p.adjustANOVA 2.94e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
NCSTN 11452
GRB10 11433
SH2B2 11393
PRKACA 11363
LAMC1 11344
ATP6AP1 11341
AP2A1 11340
WASF1 11328
CTNNA1 11326
NCKAP1L 11304
ATP6V0A1 11283
MAPKAPK3 11249
MAPK1 11193
PTK2B 11185
PRKCD 11168
FLT1 11152
TCIRG1 11138
MAPK14 11115
RPS6KA1 11103
ATP6V0D1 11016

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NCSTN 11452
GRB10 11433
SH2B2 11393
PRKACA 11363
LAMC1 11344
ATP6AP1 11341
AP2A1 11340
WASF1 11328
CTNNA1 11326
NCKAP1L 11304
ATP6V0A1 11283
MAPKAPK3 11249
MAPK1 11193
PTK2B 11185
PRKCD 11168
FLT1 11152
TCIRG1 11138
MAPK14 11115
RPS6KA1 11103
ATP6V0D1 11016
ATP6V0C 10995
TGFA 10983
FES 10973
ADAM17 10964
MMP9 10920
PTPN18 10915
FURIN 10905
NCF4 10813
LYN 10810
WASF2 10807
NCF2 10793
GRB2 10733
EPN1 10697
RIT1 10696
CDK5 10628
RAC1 10624
PTPN1 10623
GAB2 10528
SPRED2 10499
PTPN6 10446
PSEN1 10429
CYFIP1 10420
HGF 10417
CRK 10387
DNM2 10373
PTPRJ 10340
SHB 10331
MKNK1 10325
CLTC 10304
RNF41 10276
VAV1 10226
AP2A2 10223
ELMO2 10190
CYBA 10173
MAP2K1 10148
PXN 10135
RALB 10104
ADAP1 10090
CDH5 10065
PAK1 10043
MAPK7 10035
PDGFRA 10015
ADAM10 9992
ATP6V1D 9982
LYL1 9959
TNS3 9957
CBL 9903
ATP6V1C1 9900
MEF2A 9891
LAMB1 9873
STAT6 9852
DLG4 9813
EP300 9789
TEC 9787
ATP6V0B 9782
MAPK3 9750
STAT3 9739
NEDD4 9677
CTNNB1 9670
CYBB 9660
MAPK13 9645
SH3GL1 9632
FLT3 9618
SHC1 9541
ATP6V1A 9534
KL 9509
APH1B 9474
ID2 9463
ATP6V1B2 9436
IRS2 9427
RHOA 9401
CSK 9400
INSR 9393
SPHK1 9380
ABI1 9373
KIDINS220 9339
HGS 9317
PTK6 9263
SRF 9254
PTPN2 9173
PIK3CB 9126
PTPRO 9048
PAK2 9042
NCKAP1 8861
MAPKAPK2 8852
AP2M1 8799
GALNT3 8797
LAMB3 8786
SPINT1 8770
STAT5B 8742
PDPK1 8710
ROCK1 8695
GAB1 8670
PDGFC 8634
PRKCB 8577
DUSP3 8510
GGA3 8491
EPS15L1 8461
RAB4B 8449
ATP6V0E1 8417
VAV3 8413
TRIB1 8411
CDC42 8342
HPN 8299
ATP6V1E1 8198
PRKCE 8190
ID1 8155
NCOR1 8153
SOCS6 8074
AP2S1 8045
THBS3 7964
POLR2A 7852
ITGAV 7847
FOSL1 7839
STAT5A 7833
COL6A3 7824
PTPN12 7724
ITPR2 7716
FRS3 7701
COL9A3 7628
DOCK1 7594
PTPRU 7478
MEMO1 7465
PPP2CB 7451
STAM2 7431
RAP1A 7335
JUNB 7257
NCF1 7245
MAP2K2 7222
VRK3 7206
USP8 7180
SPINT2 7173
CLTA 7164
DIAPH1 7128
AHCYL1 7116
ATP6V1H 7104
MEF2D 7093
PSENEN 7091
RAP1B 6962
RANBP9 6938
IGF1R 6913
PPP2CA 6806
PDGFRB 6793
ITCH 6755
GTF2F1 6738
SH2B3 6700
ROCK2 6611
FGFR1 6607
PPP2R5D 6601
PTPN11 6524
PIK3R2 6511
AKT1 6498
GABRB3 6447
TNS4 6321
GTF2F2 6257
RASA1 6250
NRP1 6221
ANOS1 6211
UBC 6135
KRAS 6132
CDC37 6119
PCSK5 6103
EPS15 6059
PAG1 6054
DNM1 5998
SH3KBP1 5885
MST1 5836
VEGFA 5648
POLR2J 5598
VEGFC 5567
AKT2 5502
ELMO1 5455
BAX 5446
GFAP 5346
PDGFA 5341
EGF 5267
CRKL 5250
PPP2R1A 5189
POLR2E 5109
RAPGEF1 5102
NRAS 4907
RANBP10 4868
PCSK6 4846
YWHAB 4721
SOCS1 4688
THBS1 4645
MAPKAP1 4588
HNRNPM 4537
JAK2 4428
RPS6KA2 4384
BRAF 4367
ADORA2A 4267
POLR2F 4256
POLR2G 4175
SPRY2 3882
ATP6V1F 3811
SPRED1 3532
DNM3 3523
COL4A2 3049
ARF6 3007
NTRK3 2984
ITGB3 2944
AP2B1 2910
FOS 2787
VAV2 2755
PIK3R3 2676
APH1A 2563
ATF1 2556
TRIB3 2492
CTNND1 2473
APOE 2448
AREG 2386
TCF12 2381
NAB1 2340
MAP2K5 2256
CAV1 2229
LAMA4 2136
PIK3CA 2133
HBEGF 2064
POLR2L 2016
TAB2 1975
EGR3 1815
NELFB 1812
GABRG2 1791
MTOR 1777
COL9A2 1737
REST 1524
LAMA1 1497
PGF 1432
CDK5R1 1363
HNRNPF 1319
TF 1246
ESRP2 1043
FLRT2 1038
UBB 1026
STAM 907
LAMA5 751
RPS6KA3 649
ERBB3 599
PTK2 388
CHD4 290
PLG 218
PTPN3 190
PPP2R1B 89
ERBIN 87
TLR9 -36
LAMB2 -47
EREG -249
ARHGEF7 -477
POLR2C -494
AXL -591
ATF2 -657
FER -690
DNAL4 -764
CYFIP2 -775
FGFRL1 -781
NCBP1 -942
SPARC -1002
MLST8 -1064
FRS2 -1144
EPGN -1241
CALM1 -1245
MAPK12 -1261
SPRY1 -1274
S100B -1351
WASF3 -1364
COL4A4 -1448
HSPB1 -1544
RAB4A -1669
PIK3C3 -1718
COL4A3 -1796
FGFBP2 -1815
BAIAP2 -1877
FGF23 -1952
GRAP2 -2088
PIK3R4 -2097
DUSP4 -2116
FOSB -2206
JUND -2283
PRKCA -2408
DUSP7 -2452
BRK1 -2561
FLT4 -2628
JUP -2668
STUB1 -2688
PTBP1 -2842
YES1 -2846
CUL5 -2872
NCK2 -2908
ATP6V1C2 -2926
FGFBP3 -2969
SOS1 -2983
ESR1 -3021
DUSP6 -3055
ITGB1 -3073
MST1R -3290
POLR2B -3384
LAMA2 -3418
UBA52 -3490
TIAM1 -3517
NRG4 -3673
ITPR1 -3676
ITGA2 -3700
MXD4 -3719
TIA1 -3757
NTRK1 -3793
FGF22 -3881
ATP6V1E2 -3894
POLR2I -3929
NAB2 -3964
CREB1 -3977
EGR1 -4009
HSP90AA1 -4016
DOCK7 -4084
ID3 -4133
SHC2 -4426
TIAL1 -4501
FGFR4 -4539
MAPK11 -4641
ATP6V1G1 -4775
ADAM12 -4810
POLR2K -4907
FYN -5211
RICTOR -5264
HRAS -5273
DOCK3 -5299
PDGFD -5417
FGFR2 -5834
ELK1 -5884
PAK3 -5908
TPH1 -5977
PRKCZ -6016
MEF2C -6025
IRS1 -6033
PTPRS -6062
ITPR3 -6139
ERBB2 -6142
CHEK1 -6143
PLAT -6194
POLR2H -6200
FGF2 -6231
SH2D2A -6241
SGK1 -6264
AAMP -6320
RALA -6392
PSEN2 -6393
SRC -6396
ATP6V0A2 -6587
EGR2 -6603
SHC3 -6615
RBFOX2 -6652
PRR5 -6787
POLR2D -6856
CILP -6897
MUC20 -6993
NOS3 -7169
NRG1 -7233
HNRNPH1 -7320
FGF7 -7330
RALGDS -7432
COL6A2 -7450
STMN1 -7679
MATK -7917
NRP2 -8032
LAMC3 -8137
HNRNPA1 -8155
ABI2 -8174
ITGA3 -8259
THBS4 -8348
FGF9 -8476
COL6A1 -8623
AKT3 -8810
PIK3R1 -8831
NCK1 -8975
WWOX -9080
PTPRK -9142
ATP6V1G2 -9143
PDE3B -9157
RPS6KA5 -9386
PLCG1 -9412
STAT1 -9448
ATP6V0E2 -9456
VEGFB -9481
LCK -9556
PDGFB -9562
NCBP2 -9631
RPS27A -9723
PRKACB -9863
WWP1 -9985
LRIG1 -9995
FLT3LG -10078
GRAP -10095
THEM4 -10102
KIT -10114


tRNA processing

tRNA processing
1357
set tRNA processing
setSize 134
pANOVA 8.34e-12
s.dist -0.342
p.adjustANOVA 2.83e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
NDC1 -10077
MT-TP -10070
RPP40 -10069
ALKBH8 -9977
METTL1 -9815
NUP35 -9726
NUP88 -9668
SEH1L -9574
TRMT11 -9508
TYW1 -9363
QTRT1 -9338
TRMT61B -9259
PUS7 -9235
TYW3 -9215
TSEN2 -8784
RPP25 -8688
TRMT13 -8669
RPP30 -8640
TSEN15 -8515
RAN -8475

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NDC1 -10077
MT-TP -10070
RPP40 -10069
ALKBH8 -9977
METTL1 -9815
NUP35 -9726
NUP88 -9668
SEH1L -9574
TRMT11 -9508
TYW1 -9363
QTRT1 -9338
TRMT61B -9259
PUS7 -9235
TYW3 -9215
TSEN2 -8784
RPP25 -8688
TRMT13 -8669
RPP30 -8640
TSEN15 -8515
RAN -8475
NUP43 -8368
NUP160 -8357
TRMT10C -8306
NUP107 -8285
OSGEP -7996
NUP188 -7953
TP53RK -7907
POP5 -7837
TPRKB -7836
TSEN54 -7696
RPP38 -7683
PUS1 -7669
ADAT2 -7613
GTPBP3 -7547
NUP205 -7516
THG1L -7403
NUP54 -7131
TRMT61A -7077
NUP155 -7061
MTO1 -7022
DDX1 -6788
THADA -6715
NUP93 -6458
TRMT1 -6407
LCMT2 -6376
EPRS1 -6350
MT-ND2 -6095
CDKAL1 -5902
XPOT -5659
POP1 -5627
FAM98B -5622
TRNT1 -5539
MT-ND3 -5522
ELAC2 -5385
LAGE3 -5360
TRIT1 -5352
NUP133 -5346
TRMU -5295
FTSJ1 -5188
TRMT44 -5173
TRMT5 -5160
MT-CO3 -5157
WDR4 -5100
MT-RNR1 -5094
MT-ND1 -5075
C2orf49 -4997
CTU2 -4830
RTRAF -4768
RPP21 -4260
NUP42 -4045
CPSF4 -4025
NUP210 -3949
TPR -3744
NUP85 -3427
AAAS -3332
MT-ND6 -2833
MT-CO2 -2523
NUP62 -2410
TRMT112 -2296
NUP37 -2275
RPP14 -2204
MT-ATP6 -2202
MT-CYB -2032
TRMT12 -1884
URM1 -1729
PRORP -1720
POM121C -1710
POP7 -1436
ADAT1 -1317
RANBP2 -1141
MT-ND5 -931
CSTF2 -856
TRDMT1 -835
MT-TS1 -757
CPSF1 -561
RTCB -467
MT-CO1 -454
MT-RNR2 -408
POM121 -142
POP4 56
NSUN6 84
MT-ATP8 189
NUP153 254
PUS3 1168
NSUN2 1256
TYW5 1485
MT-ND4L 2323
QTRT2 2548
NUP50 2638
MT-TC 2702
MT-TF 2765
DUS2 2832
MT-TE 2931
HSD17B10 2981
MT-TA 2997
MT-TV 3363
MT-TN 3398
ZBTB8OS 4008
MT-ND4 4493
MT-TL1 4517
RAE1 5007
ADAT3 5211
CTU1 5266
MT-TY 5373
CLP1 5591
NUP98 5874
TRMT10A 6917
SEC13 7506
TRMT6 8246
TSEN34 9433
NUP58 9577
NUP214 10131
RPPH1 10428
TRMT9B 11020


Signaling by ROBO receptors

Signaling by ROBO receptors
1128
set Signaling by ROBO receptors
setSize 199
pANOVA 8.54e-12
s.dist -0.281
p.adjustANOVA 2.83e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
NELL2 -10152
RPL23A -9979
RPL3 -9957
RPL5 -9881
PRKACB -9863
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
ROBO3 -9694
RPS25 -9664
RPL22 -9659
NCBP2 -9631
RPS2 -9591
EVL -9560
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NELL2 -10152
RPL23A -9979
RPL3 -9957
RPL5 -9881
PRKACB -9863
RPS3A -9834
RPL7 -9765
RPS27A -9723
RPS6 -9699
RPL14 -9698
ROBO3 -9694
RPS25 -9664
RPL22 -9659
NCBP2 -9631
RPS2 -9591
EVL -9560
RPL4 -9549
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
RPL32 -9345
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
PFN2 -9148
RPL11 -9117
RPL17 -9116
RPL27A -9048
RPS5 -9042
RPL10 -9031
NCK1 -8975
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
UPF3A -8795
RPL31 -8769
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
AKAP5 -8634
RPL29 -8621
RPS16 -8579
RPS14 -8541
PSMB9 -8503
RPS10 -8494
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
RPS28 -8083
RNPS1 -8030
GSPT2 -7995
RPS11 -7975
RPL38 -7968
RPL37 -7861
RPL27 -7810
RPS19 -7806
PSME1 -7778
RPL13 -7671
RPL41 -7561
RPL36 -7493
PSMA5 -7476
PSME2 -7327
RPL37A -6833
RPL9 -6821
RPS24 -6818
MAGOHB -6726
RPS15 -6703
RPL36AL -6646
RPSA -6629
PSMA3 -6433
SRC -6396
RPL8 -6101
RPLP1 -6018
PAK3 -5908
UPF3B -5843
LDB1 -4826
MAGOH -4678
PSMC5 -4553
ARHGAP39 -4144
PSMB10 -4050
RPL28 -3873
FAU -3618
PSMB1 -3610
UBA52 -3490
GPC1 -3369
PAK6 -3356
PABPC1 -2991
SOS1 -2983
NCK2 -2908
PSMA2 -2823
PSMA4 -2764
PSMD10 -2515
PRKCA -2408
USP33 -2081
GSPT1 -2025
CLASP2 -1947
RPL39L -1661
NTN1 -1643
RBM8A -1499
CXCR4 -1239
RPS26 -1154
NCBP1 -942
LHX4 -539
RPS27L -496
PSMB8 -438
PAK4 -406
CUL2 -38
DAG1 261
RPS4Y1 331
PSMC4 605
PSMB4 642
PSMC3 916
PSMD14 941
ROBO1 973
UBB 1026
UPF2 1281
EIF4A3 1507
PSMB2 1760
PSME4 1818
RPS9 1841
PSMD7 2084
SRGAP3 2421
PSMA1 3111
SLIT3 3414
SEM1 3454
ENAH 3578
PSMD13 3766
RBX1 3957
ABL2 4134
PSMF1 4259
PSMD3 4297
PSMC2 4543
PSMC1 4827
PSMC6 4959
RPL3L 5150
PSMA6 5209
PSMD8 5687
RPL26L1 6001
PPP3CB 6126
ABL1 6127
UBC 6135
NRP1 6221
PSMD12 6820
ETF1 6835
ELOC 6974
CLASP1 6986
PSMD6 7307
PSMB6 7399
PRKAR2A 7426
ELOB 7435
PSMD5 7646
PSMD11 7775
PSMA7 7840
PSMB3 8005
PSMD2 8139
PSMD1 8184
PSMB5 8265
CDC42 8342
PFN1 8397
PSMB7 8460
SLIT1 8535
PSME3 8716
PSMD9 8766
PAK2 9042
RHOA 9401
CASC3 9610
SOS2 9744
CAP1 9934
SRGAP1 9993
PAK1 10043
PSMD4 10088
VASP 10286
ZSWIM8 10300
EIF4G1 10506
RAC1 10624
SRGAP2 10779
MYO9B 10832
PRKACA 11363


Metabolism of amino acids and derivatives

Metabolism of amino acids and derivatives
636
set Metabolism of amino acids and derivatives
setSize 324
pANOVA 9.44e-12
s.dist -0.22
p.adjustANOVA 3.06e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
GLS -10099
SARDH -10052
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
DBH -9778
RPL7 -9765
SRM -9746
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
BCKDHB -9648
LARS1 -9637
RPS2 -9591
IL4I1 -9567
RPL4 -9549
AZIN2 -9536

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GLS -10099
SARDH -10052
RPL23A -9979
RPL3 -9957
RPL5 -9881
RPS3A -9834
DBH -9778
RPL7 -9765
SRM -9746
RPS27A -9723
RPS6 -9699
RPL14 -9698
RPS25 -9664
RPL22 -9659
BCKDHB -9648
LARS1 -9637
RPS2 -9591
IL4I1 -9567
RPL4 -9549
AZIN2 -9536
IDO1 -9528
RIMKLB -9515
RPL21 -9511
RPL34 -9492
RPS20 -9413
RPL13A -9402
RPS23 -9387
LIPT1 -9372
RPL32 -9345
ENOPH1 -9320
RPL6 -9309
RPS3 -9298
RPL35A -9291
RPS12 -9270
GAMT -9258
RPLP0 -9227
RPL12 -9177
RPS27 -9175
RPS7 -9165
RPLP2 -9163
RPL11 -9117
RPL17 -9116
SERINC5 -9110
CARNMT1 -9074
PPM1K -9062
RPL27A -9048
RPS5 -9042
RPL10 -9031
IARS1 -8999
ALDH18A1 -8956
RPL30 -8930
RPL10A -8928
RPL36A -8909
RPL24 -8901
RPL18A -8896
RPS15A -8883
RPL18 -8863
RPS8 -8861
RPL31 -8769
SLC5A5 -8748
RPS13 -8724
RPL26 -8706
RPS4X -8648
RPS29 -8637
RPL39 -8635
ACADSB -8628
RPL29 -8621
RPS16 -8579
RPS14 -8541
PSMB9 -8503
RPS10 -8494
MTR -8432
KARS1 -8380
RPL23 -8373
RPL19 -8338
RPS21 -8330
RPS18 -8321
RPL7A -8286
RPS17 -8281
MCCC2 -8250
RPL22L1 -8202
RPL35 -8183
RPL15 -8169
TSTD1 -8143
AGMAT -8105
RPS28 -8083
AASS -8059
GLS2 -8010
AIMP1 -7990
RPS11 -7975
RPL38 -7968
MCCC1 -7959
SEPSECS -7958
SLC25A10 -7923
RPL37 -7861
RPL27 -7810
RPS19 -7806
PSME1 -7778
ASNS -7772
GOT2 -7738
HDC -7734
RPL13 -7671
SCLY -7645
RPL41 -7561
RPL36 -7493
PSMA5 -7476
PSME2 -7327
LIPT2 -7207
FTCD -7191
GLDC -7164
SECISBP2 -6992
DARS1 -6939
IVD -6935
NAALAD2 -6925
RPL37A -6833
ECHS1 -6827
RPL9 -6821
CARNS1 -6820
RPS24 -6818
GCDH -6784
RPS15 -6703
RPL36AL -6646
RPSA -6629
MTAP -6590
EEFSEC -6493
SRR -6437
PSMA3 -6433
TPO -6390
EPRS1 -6350
PAOX -6280
HGD -6170
LIAS -6141
RPL8 -6101
CKMT2 -6100
SARS1 -6044
RPLP1 -6018
TPH1 -5977
DUOX1 -5968
PSTK -5710
NQO1 -5705
IDO2 -5605
HYKK -5506
OAZ3 -5122
HIBADH -4931
GOT1 -4852
GPT -4834
AMT -4728
NDUFAB1 -4616
PSMC5 -4553
PYCR2 -4482
KYAT1 -4406
SERINC4 -4293
PSMB10 -4050
SLC25A15 -4035
DIO1 -4000
RARS1 -3944
RPL28 -3873
QARS1 -3758
PDHA1 -3634
FAU -3618
PSMB1 -3610
MRI1 -3570
AMDHD1 -3546
UBA52 -3490
AIMP2 -3343
GCSH -3198
GATM -3135
ODC1 -3122
KMO -2968
DBT -2941
AMD1 -2877
PSMA2 -2823
PSMA4 -2764
EEF1E1 -2716
NMRAL1 -2539
PSMD10 -2515
AHCY -2510
PDHB -2499
DLST -2278
DLAT -1870
ACAT1 -1835
ADO -1745
RPL39L -1661
ACMSD -1541
GCAT -1446
RPS26 -1154
BCAT2 -1099
SLC25A12 -1081
KYAT3 -1013
SLC25A13 -840
PRODH -833
PNMT -794
SMS -776
CTH -637
RPS27L -496
PSMB8 -438
SLC25A21 -423
INMT -384
RIDA -303
ASRGL1 -248
PDHX -213
HIBCH -70
IYD 22
RPS4Y1 331
SLC6A12 334
SHMT1 504
PSMC4 605
PSMB4 642
APIP 804
QDPR 887
RIMKLA 904
PSMC3 916
PSMD14 941
GLUD1 1127
CKB 1468
DDO 1575
PSMB2 1760
PSME4 1818
RPS9 1841
GRHPR 1970
PXMP2 1972
ALDH9A1 2030
ASPA 2080
PSMD7 2084
PYCR1 2475
ADI1 2478
TXN2 2614
GNMT 2920
HSD17B10 2981
PSMA1 3111
SEM1 3454
ACAD8 3470
ARG2 3654
PSMD13 3766
ALDH7A1 4032
ALDH6A1 4067
PSMF1 4259
PSMD3 4297
TPH2 4323
PSMC2 4543
TST 4568
AUH 4771
PSMC1 4827
SERINC1 4871
NAGS 4938
PSMC6 4959
SLC7A5 5072
RPL3L 5150
PSMA6 5209
AANAT 5309
GPT2 5355
PIPOX 5412
SDS 5616
PSMD8 5687
GADL1 5942
RPL26L1 6001
AZIN1 6420
HNMT 6423
SLC44A1 6488
SDSL 6596
MPST 6726
MTRR 6728
SMOX 6816
PSMD12 6820
PHGDH 6935
SLC3A2 7012
BCKDHA 7235
PSMD6 7307
MARS1 7358
PSMB6 7399
DLD 7581
PSMD5 7646
PSMD11 7775
KYNU 7788
PSMA7 7840
PSPH 7893
SLC6A8 7966
PSMB3 8005
SEPHS2 8084
PSMD2 8139
PSMD1 8184
PSMB5 8265
HAAO 8357
PSMB7 8460
ETHE1 8616
SERINC3 8631
PSME3 8716
SLC36A4 8717
OGDH 8751
PSMD9 8766
HAL 9029
PCBD1 9082
CKM 9161
SAT1 9171
CHDH 9390
DHTKD1 9518
OAZ1 9713
PSAT1 9730
PHYKPL 9859
TXNRD1 9890
CSAD 9906
SERINC2 10023
ARG1 10061
PSMD4 10088
GSTZ1 10096
OAT 10162
HPD 10179
PAPSS1 10336
CRYM 10349
OAZ2 10400
ASL 10407
TMLHE 10440
BCAT1 10485
SLC25A44 10614
FAH 10731
BCKDK 10789
CBSL 10916
ALDH4A1 11032
GSR 11051
SUOX 11174
CBS 11232
GLUL 11243
PAPSS2 11267
AFMID 11362


ER to Golgi Anterograde Transport

ER to Golgi Anterograde Transport
325
set ER to Golgi Anterograde Transport
setSize 129
pANOVA 1.91e-11
s.dist 0.342
p.adjustANOVA 6.05e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
F5 11434
SERPINA1 11407
COPG1 11142
TGFA 10983
CD55 10914
SEC24D 10803
DCTN4 10682
ARF1 10610
COPA 10521
DCTN2 10412
PREB 10364
ACTR1A 10310
RAB1B 10055
COG7 9987
RAB1A 9971
CTSZ 9943
NSF 9870
GORASP1 9633
KDELR1 9613
CAPZB 9575

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
F5 11434
SERPINA1 11407
COPG1 11142
TGFA 10983
CD55 10914
SEC24D 10803
DCTN4 10682
ARF1 10610
COPA 10521
DCTN2 10412
PREB 10364
ACTR1A 10310
RAB1B 10055
COG7 9987
RAB1A 9971
CTSZ 9943
NSF 9870
GORASP1 9633
KDELR1 9613
CAPZB 9575
DCTN1 9558
CAPZA1 9530
LMAN2 9480
ARF3 9465
SEC16A 9460
SEC24A 9414
GOLGA2 9412
ARF4 9348
CTSC 9276
PPP6R1 9179
TRAPPC1 9087
SEC24C 8993
SEC16B 8899
COPB2 8898
COPG2 8709
STX5 8547
CSNK1D 8475
COG4 8402
ARF5 8313
DYNC1LI1 8276
COPE 8230
CAPZA2 8225
MIA2 8200
TFG 8124
TMED9 8028
F8 8026
COPB1 7997
COL7A1 7971
SPTB 7702
GBF1 7683
DYNC1LI2 7644
YKT6 7621
DCTN6 7540
NAPG 7516
SEC13 7506
ARFGAP3 7424
SEC24B 7352
SEC23A 7129
ARCN1 6965
SAR1B 6893
DYNC1I2 6705
NAPA 6660
DCTN3 6625
TRAPPC9 6548
KDELR2 6387
SCFD1 6297
SEC22B 6272
TMEM115 6183
GOSR2 5986
ACTR10 5886
ANK1 5655
TMED2 5345
MCFD2 5134
SPTBN5 4732
TRAPPC3 4443
SEC31A 4346
ARFGAP2 4331
CD59 4252
CNIH2 4186
SPTA1 4063
TMED7 3978
TBC1D20 3947
PPP6R3 3723
TMED3 3420
TRAPPC5 3257
NAPB 3180
ARFGAP1 2978
DYNC1I1 2879
TRAPPC10 2565
USO1 2424
AREG 2386
COG5 2352
PPP6C 2138
DYNC1H1 1705
LMAN2L 1586
DYNLL1 1530
TRAPPC6B 1327
KDELR3 869
SEC23IP 737
COPZ1 412
COG8 406
DCTN5 297
SPTBN2 -220
BET1L -1574
TRAPPC2L -1855
COG3 -2175
TRAPPC4 -2490
CNIH1 -2698
GOSR1 -3080
SEC22C -3143
MIA3 -3686
GOLGB1 -4004
TMED10 -4413
CNIH3 -4435
DYNLL2 -4904
COG2 -5554
ANKRD28 -5681
COPZ2 -5974
BET1 -6342
COG6 -6645
TRAPPC2 -7043
COG1 -7045
ANK3 -7751
SEC22A -7808
STX17 -8013
SPTBN1 -8138
LMAN1 -8522
SPTAN1 -9461
TRAPPC6A -9543


Transport to the Golgi and subsequent modification

Transport to the Golgi and subsequent modification
1290
set Transport to the Golgi and subsequent modification
setSize 155
pANOVA 3.74e-10
s.dist 0.291
p.adjustANOVA 1.16e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
F5 11434
SERPINA1 11407
B4GALT5 11150
COPG1 11142
TGFA 10983
CD55 10914
MAN1A1 10830
SEC24D 10803
DCTN4 10682
ARF1 10610
COPA 10521
DCTN2 10412
PREB 10364
ACTR1A 10310
MAN2A2 10274
ST3GAL4 10218
RAB1B 10055
COG7 9987
RAB1A 9971
CTSZ 9943

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
F5 11434
SERPINA1 11407
B4GALT5 11150
COPG1 11142
TGFA 10983
CD55 10914
MAN1A1 10830
SEC24D 10803
DCTN4 10682
ARF1 10610
COPA 10521
DCTN2 10412
PREB 10364
ACTR1A 10310
MAN2A2 10274
ST3GAL4 10218
RAB1B 10055
COG7 9987
RAB1A 9971
CTSZ 9943
NSF 9870
GORASP1 9633
KDELR1 9613
CAPZB 9575
DCTN1 9558
CHST8 9536
CAPZA1 9530
LMAN2 9480
ARF3 9465
SEC16A 9460
SEC24A 9414
GOLGA2 9412
ARF4 9348
CTSC 9276
PPP6R1 9179
TRAPPC1 9087
SEC24C 8993
SEC16B 8899
COPB2 8898
COPG2 8709
STX5 8547
CSNK1D 8475
COG4 8402
ARF5 8313
DYNC1LI1 8276
COPE 8230
CAPZA2 8225
MIA2 8200
TFG 8124
TMED9 8028
F8 8026
COPB1 7997
COL7A1 7971
MGAT4B 7889
B4GALT1 7763
SPTB 7702
GBF1 7683
DYNC1LI2 7644
YKT6 7621
DCTN6 7540
NAPG 7516
SEC13 7506
MGAT1 7476
ARFGAP3 7424
SEC24B 7352
SEC23A 7129
ARCN1 6965
SAR1B 6893
DYNC1I2 6705
NAPA 6660
DCTN3 6625
TRAPPC9 6548
FUCA1 6469
KDELR2 6387
B4GALT4 6368
SCFD1 6297
SEC22B 6272
TMEM115 6183
GOSR2 5986
ACTR10 5886
ANK1 5655
TMED2 5345
MCFD2 5134
SPTBN5 4732
TRAPPC3 4443
SEC31A 4346
ARFGAP2 4331
CD59 4252
B4GALT6 4216
CNIH2 4186
SPTA1 4063
MGAT2 4055
TMED7 3978
TBC1D20 3947
PPP6R3 3723
TMED3 3420
TRAPPC5 3257
NAPB 3180
ARFGAP1 2978
DYNC1I1 2879
TRAPPC10 2565
USO1 2424
AREG 2386
COG5 2352
PPP6C 2138
DYNC1H1 1705
LMAN2L 1586
DYNLL1 1530
MANEA 1515
TRAPPC6B 1327
KDELR3 869
SEC23IP 737
COPZ1 412
COG8 406
DCTN5 297
SPTBN2 -220
BET1L -1574
B4GALT2 -1790
TRAPPC2L -1855
COG3 -2175
TRAPPC4 -2490
CNIH1 -2698
GOSR1 -3080
SEC22C -3143
MGAT4C -3553
CHST10 -3667
MIA3 -3686
GOLGB1 -4004
MAN2A1 -4015
MAN1A2 -4146
TMED10 -4413
CNIH3 -4435
ST8SIA6 -4572
DYNLL2 -4904
FUT8 -5277
MGAT5 -5546
COG2 -5554
ANKRD28 -5681
B4GALT3 -5794
COPZ2 -5974
MGAT3 -6227
BET1 -6342
COG6 -6645
TRAPPC2 -7043
COG1 -7045
MGAT4A -7072
ANK3 -7751
SEC22A -7808
STX17 -8013
SPTBN1 -8138
LMAN1 -8522
ST6GAL1 -8538
SPTAN1 -9461
TRAPPC6A -9543
MAN1C1 -9944


Hemostasis

Hemostasis
494
set Hemostasis
setSize 548
pANOVA 3.99e-10
s.dist 0.156
p.adjustANOVA 1.21e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
P2RX1 11442
F5 11434
PHF21A 11432
F12 11417
SIRPA 11414
SERPINA1 11407
THBD 11404
SH2B2 11393
P2RY1 11378
QSOX1 11369
PRKACA 11363
CD63 11355
MERTK 11332
FGR 11323
NFE2 11293
STXBP2 11285
TIMP1 11275
ITGAM 11269
SLC16A3 11262
ITGAX 11231

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
P2RX1 11442.0
F5 11434.0
PHF21A 11432.0
F12 11417.0
SIRPA 11414.0
SERPINA1 11407.0
THBD 11404.0
SH2B2 11393.0
P2RY1 11378.0
QSOX1 11369.0
PRKACA 11363.0
CD63 11355.0
MERTK 11332.0
FGR 11323.0
NFE2 11293.0
STXBP2 11285.0
TIMP1 11275.0
ITGAM 11269.0
SLC16A3 11262.0
ITGAX 11231.0
FCER1G 11216.0
SLC8A1 11210.0
MAPK1 11193.0
GTPBP2 11180.0
PRKCD 11168.0
MAPK14 11115.0
DOCK5 11090.0
CD177 11068.0
CYB5R1 11052.0
MICAL1 11046.0
TOR4A 11002.0
FERMT3 10998.0
CD36 10947.0
CEACAM3 10932.0
APLP2 10928.0
GNA15 10907.0
ALDOA 10868.0
ITGB2 10861.0
MRVI1 10860.0
CLU 10812.0
LYN 10810.0
KCNMA1 10805.0
GRB2 10733.0
GNG5 10721.0
DOCK4 10715.0
SERPINB2 10710.0
ANXA2 10704.0
ARRB2 10688.0
RHOG 10635.0
CDK5 10628.0
RAC1 10624.0
PTPN1 10623.0
APBB1IP 10622.0
RCOR1 10600.0
MAFG 10542.0
PRKAR1A 10510.0
PLAUR 10490.0
KIF1B 10454.0
PTPN6 10446.0
HGF 10417.0
PECAM1 10414.0
GNB1 10392.0
CRK 10387.0
ATP2A2 10359.0
PDE1B 10346.0
DAGLB 10338.0
ITPK1 10323.0
SCCPDH 10298.0
GNB2 10282.0
GNAI2 10264.0
SYK 10256.0
PLCG2 10244.0
ACTN4 10230.0
VAV1 10226.0
TLN1 10191.0
STIM1 10169.0
DOCK2 10155.0
CD99L2 10108.0
GNG10 10071.0
BSG 10030.0
PIK3R6 10025.0
SELL 9974.0
LHFPL2 9956.0
CAP1 9934.0
IGLV7-43 9914.0
PPP2R5B 9913.0
GAS6 9901.0
SRGN 9887.0
GNAQ 9871.0
WDR1 9868.0
ITGA5 9848.0
PPP2R5A 9827.0
ACTN1 9811.0
PLA2G4A 9803.0
CFL1 9794.0
RAD51B 9755.0
MAPK3 9750.0
CD58 9688.0
RAF1 9686.0
LRP8 9649.0
DOCK8 9616.0
IGKV1-39 9590.0
CAPZB 9575.0
GATA1 9542.0
SHC1 9541.0
CAPZA1 9530.0
JAML 9516.0
ITGA1 9515.0
KIF1C 9483.0
RHOA 9401.0
CSK 9400.0
KIF3C 9374.0
ANXA5 9269.0
CD44 9255.0
SLC7A7 9251.0
SERPINB8 9228.0
PIK3CG 9128.0
PIK3CB 9126.0
RAPGEF3 9100.0
CEACAM1 9052.0
CALU 9049.0
LAMP2 9034.0
INPP5D 9020.0
H3-3A 8985.0
TNFRSF10B 8944.0
AKAP10 8939.0
VTI1B 8933.0
H3C15 8929.5
PSAP 8894.0
KLC1 8888.0
SELPLG 8865.0
PDPK1 8710.0
HBG2 8677.0
ALB 8630.0
PRKCB 8577.0
PRCP 8518.0
KIF13B 8431.0
VAV3 8413.0
MFN2 8399.0
PFN1 8397.0
CLEC1B 8373.0
ORAI2 8345.0
GNAI3 8344.0
CDC42 8342.0
FLNA 8318.0
IRF2 8298.0
RAC2 8237.0
DGKG 8235.0
CAPZA2 8225.0
KIF5B 8197.0
PRKCE 8190.0
EHD2 8070.0
TUBA4A 8035.0
F8 8026.0
EHD1 7942.0
RHOB 7921.0
P2RX4 7897.0
ITGAV 7847.0
SRI 7820.0
TREM1 7815.0
ATP2B4 7814.0
DOCK11 7762.0
ITPR2 7716.0
SYTL4 7697.0
DOCK1 7594.0
PIK3R5 7579.0
CLEC3B 7525.0
SERPIND1 7470.0
PPP2CB 7451.0
PRKAR2A 7426.0
ITGA2B 7387.0
RAP1A 7335.0
STXBP3 7210.0
RAB5A 7154.0
DOCK6 7123.0
CD84 7112.0
SERPINE2 7081.0
GNB4 7078.0
HSPA5 7027.0
STX4 7026.0
SLC3A2 7012.0
RAP1B 6962.0
TNFRSF10D 6912.0
DGKD 6870.0
PPP2CA 6806.0
KIF9 6805.0
IGLV10-54 6741.0
PICK1 6735.0
SH2B3 6700.0
HBB 6697.0
ABHD6 6665.0
PPP2R5D 6601.0
GYPC 6561.0
PTPN11 6524.0
PIK3R2 6511.0
AKT1 6498.0
KLC3 6451.0
ATP1B3 6301.0
APP 6245.0
VCL 6193.0
GP1BB 6153.0
KRAS 6132.0
ABL1 6127.0
CD109 6110.0
ECM1 6098.0
TTN 6088.0
TGFB2 6083.0
GNAS 5944.0
CENPE 5930.0
RACGAP1 5897.0
CD99 5848.0
CD9 5818.0
KIF18B 5806.0
SDC4 5724.0
F2RL2 5667.0
GP9 5664.0
GP6 5660.0
PRKAR1B 5653.0
VEGFA 5648.0
VEGFC 5567.0
TGFB1 5504.0
KIF3B 5396.0
SELP 5380.0
PDGFA 5341.0
S100A10 5328.0
GNA13 5302.0
SERPINB6 5280.0
EGF 5267.0
YWHAZ 5202.0
PPP2R1A 5189.0
KIF27 5112.0
SLC7A5 5072.0
HBD 5065.0
TSPAN7 5060.0
SERPINE1 5005.0
KIF21B 4976.0
NRAS 4907.0
TFPI 4875.0
SLC16A8 4815.0
MAFK 4786.0
IGKV5-2 4704.0
PLEK 4699.0
THBS1 4645.0
PF4V1 4548.0
TBXA2R 4539.0
KIF4A 4526.0
GNG3 4481.0
IGLV2-11 4439.0
JAK2 4428.0
GNG8 4328.0
GLG1 4326.0
KIF23 4278.0
PROS1 4191.0
ESAM 4171.0
GP1BA 4136.0
KCNMB3 4084.0
NOS1 4024.0
GYPA 4020.0
ATP2A1 3981.0
ARRB1 3956.0
IGLC3 3928.0
PLAU 3907.0
VWF 3870.0
GYPB 3865.0
KIF20A 3824.0
DOK2 3810.0
F11R 3762.0
LCP2 3759.0
MMP1 3753.0
PHACTR2 3743.0
P2RX7 3740.0
IGKV1D-39 3734.0
ATP2A3 3651.0
ITGAL 3647.0
F2RL3 3631.0
MMRN1 3618.0
PROC 3380.0
TIMP3 3154.0
GNG2 3124.0
KCNMB1 3105.0
ANGPT2 3039.0
ITGB3 2944.0
LY6G6F 2813.0
F2R 2762.0
VAV2 2755.0
PDE2A 2733.0
HBE1 2683.0
PIK3R3 2676.0
PRKG1 2673.0
P2RY12 2608.0
ANGPT4 2529.0
TAGLN2 2525.0
GNG4 2481.0
PDE11A 2479.0
HMG20B 2387.0
SDC2 2325.0
KIF6 2255.0
CAV1 2229.0
PIK3CA 2133.0
MPL 2081.0
HBG1 2078.0
ORM1 2075.0
IGKV1-17 2037.0
KIF2C 2011.0
MGLL 1993.0
TRPC6 1988.0
MAFF 1944.0
RAD51C 1762.0
PDE5A 1677.0
MAGED2 1652.0
ABCC4 1639.0
GNGT2 1513.0
F13A1 1493.0
CABLES1 1373.0
BRPF3 1249.0
TF 1246.0
RBSN 1171.0
EHD3 1032.0
KIF19 1011.0
ADRA2A 1007.0
CHID1 786.0
RAB27B 774.0
ATP1B2 710.0
HDAC1 650.0
IGHV1-46 618.0
GNAI1 579.0
ORM2 565.0
SDC3 564.0
KIF11 545.0
CFD 461.0
MANF 445.0
PTK2 388.0
KIFC1 288.0
PLG 218.0
PPP2R1B 89.0
IGHV1-69 -113.0
VPREB3 -333.0
JMJD1C -365.0
JAM2 -368.0
VPS45 -382.0
KIF18A -394.0
KIF26A -414.0
IGLV1-44 -417.0
PCYOX1L -458.0
CABLES2 -634.0
CD48 -714.0
GNA12 -817.0
IGKV2D-28 -844.0
TMSB4X -850.0
APOOL -867.0
SPARC -1002.0
DGKQ -1073.0
SLC7A9 -1094.0
IGHV3-30 -1129.0
CALM1 -1245.0
KCNMB4 -1367.0
SERPINF2 -1375.0
IGLV1-40 -1411.0
PPIL2 -1415.0
PRKAR2B -1442.0
ENDOD1 -1464.0
A1BG -1468.0
IGKV2-28 -1472.0
IGKV3D-20 -1473.0
SLC16A1 -1491.0
KIF15 -1564.0
IGHA2 -1596.0
ITGA10 -1674.0
IGLV1-47 -1695.0
IGKV2-30 -1785.0
FN1 -1829.0
IGLV3-27 -1836.0
SLC7A11 -1956.0
PPBP -1960.0
IGKV3-20 -2065.0
PF4 -2122.0
A2M -2133.0
IGKV1-12 -2196.0
IGHM -2289.0
DGKZ -2312.0
DGKH -2353.0
PRKCA -2408.0
CTSW -2441.0
IGHV3-11 -2459.0
GRB14 -2517.0
IGLV1-36 -2563.0
PPP2R5E -2595.0
IGHV2-70 -2783.0
GNA11 -2784.0
TNFRSF10A -2801.0
YES1 -2846.0
IGLV2-23 -2848.0
ITIH4 -2921.0
IGLC7 -2940.0
SOS1 -2983.0
IGHV3-23 -2995.0
IGLV3-25 -3048.0
IGHV2-5 -3063.0
CD244 -3072.0
ITGB1 -3073.0
MFN1 -3088.0
L1CAM -3125.0
KIFC2 -3136.0
JAM3 -3168.0
IGHV4-39 -3179.0
AK3 -3205.0
GPC1 -3369.0
CARMIL1 -3463.0
TMX3 -3613.0
CDK2 -3614.0
ITPR1 -3676.0
WEE1 -3696.0
ITGA2 -3700.0
IGLV4-69 -3702.0
IGHA1 -3787.0
IGKV1-5 -3791.0
KIFAP3 -3831.0
IGHV4-59 -3832.0
IGLC1 -3870.0
GNG11 -3895.0
IGKC -3956.0
TEX264 -4024.0
DOCK7 -4084.0
IGHV3-13 -4159.0
KLC4 -4248.0
KIF28P -4361.0
IGLV8-61 -4469.0
ZFPM1 -4486.0
MYB -4488.0
IGHV3-7 -4523.0
SLC8A3 -4584.0
KIF16B -4619.0
DAGLA -4626.0
IGLC2 -4647.0
NHLRC2 -4700.0
ABHD12 -4829.0
GNB5 -4864.0
ZFPM2 -5051.0
IGHV3-53 -5054.0
IGKV1-33 -5088.0
TRPC3 -5092.0
IGLV2-8 -5148.0
PPP2R5C -5198.0
FYN -5211.0
PAFAH2 -5224.0
SLC7A8 -5233.0
HRAS -5273.0
DOCK3 -5299.0
IGHV1-2 -5353.0
ANGPT1 -5449.0
KLC2 -5453.0
SH2B1 -5489.0
GUCY1B2 -5595.0
IGLV7-46 -5638.0
IGLV1-51 -5706.0
OLA1 -5737.0
ORAI1 -5790.0
GNG7 -5880.0
IRF1 -5925.0
PRKCZ -6016.0
IGLV3-12 -6030.0
GP5 -6093.0
ATP1B1 -6117.0
GNB3 -6125.0
RASGRP2 -6127.0
ITPR3 -6139.0
PLAT -6194.0
IGHV3-48 -6262.0
IGKV3-15 -6284.0
ATP2B1 -6310.0
AAMP -6320.0
IGLV6-57 -6338.0
IGLV3-1 -6354.0
PTGIR -6377.0
SRC -6396.0
IGHV4-34 -6414.0
GATA2 -6470.0
PPIA -6498.0
IGLV5-45 -6611.0
CBX5 -6643.0
JCHAIN -6676.0
SPN -6680.0
SELENOP -6746.0
KIF21A -6834.0
KIF2A -6844.0
HDAC2 -6871.0
IGKV1-16 -6894.0
TGFB3 -6903.0
KIF5A -6961.0
ITIH3 -7066.0
MIF -7102.0
CDC37L1 -7116.0
KLKB1 -7165.0
NOS3 -7169.0
PROCR -7182.0
KIF20B -7260.0
IGLV2-14 -7284.0
KDM1A -7314.0
IGKV4-1 -7319.0
KIF26B -7360.0
IGLV3-19 -7364.0
LGALS3BP -7405.0
SOD1 -7420.0
CEACAM8 -7546.0
SERPING1 -7610.0
OLR1 -7621.0
ITGA4 -7628.0
SIN3A -7740.0
IGLV2-18 -8002.0
SLC7A6 -8043.0
P2RX5 -8188.0
ITGA3 -8259.0
CEACAM6 -8277.0
IGHV3-33 -8309.0
CD74 -8337.0
IGLV3-21 -8363.0
PDE9A -8487.0
DGKE -8629.0
DOCK10 -8766.0
PRKG2 -8799.0
DGKA -8817.0
PIK3R1 -8831.0
C1QBP -9093.0
CD2 -9111.0
CD47 -9164.0
TP53 -9170.0
FAM3C -9260.0
PRTN3 -9350.0
RASGRP1 -9394.0
PLCG1 -9412.0
PRKCQ -9424.0
KIF3A -9438.0
IGKV3-11 -9449.0
LAT -9470.0
VEGFB -9481.0
ITGA6 -9532.0
LCK -9556.0
PDGFB -9562.0
PRKCH -9600.0
DOCK9 -9811.0
KIF22 -9850.0
PRKACB -9863.0
AKAP1 -9870.0
DGKK -9915.0
HABP4 -10030.0
GATA3 -10071.0
KIF5C -10128.0
SIRPG -10144.0


Asparagine N-linked glycosylation

Asparagine N-linked glycosylation
84
set Asparagine N-linked glycosylation
setSize 269
pANOVA 4.67e-10
s.dist 0.221
p.adjustANOVA 1.38e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
F5 11434
NPL 11416
SERPINA1 11407
B4GALT5 11150
COPG1 11142
ASGR2 11123
NEU1 11082
ST6GALNAC3 11069
ST3GAL2 11056
TGFA 10983
OS9 10951
CD55 10914
CTSA 10842
MAN1A1 10830
SEC24D 10803
DCTN4 10682
ARF1 10610
COPA 10521
EDEM2 10457
DCTN2 10412

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
F5 11434
NPL 11416
SERPINA1 11407
B4GALT5 11150
COPG1 11142
ASGR2 11123
NEU1 11082
ST6GALNAC3 11069
ST3GAL2 11056
TGFA 10983
OS9 10951
CD55 10914
CTSA 10842
MAN1A1 10830
SEC24D 10803
DCTN4 10682
ARF1 10610
COPA 10521
EDEM2 10457
DCTN2 10412
PREB 10364
ACTR1A 10310
MAN2A2 10274
ST3GAL4 10218
GLB1 10217
RAD23B 10127
RAB1B 10055
COG7 9987
RAB1A 9971
CTSZ 9943
NSF 9870
GORASP1 9633
KDELR1 9613
CAPZB 9575
DCTN1 9558
CHST8 9536
MPDU1 9532
CAPZA1 9530
LMAN2 9480
ARF3 9465
SEC16A 9460
SEC24A 9414
GOLGA2 9412
ARF4 9348
UGGT2 9278
CTSC 9276
PPP6R1 9179
NANS 9176
TRAPPC1 9087
ST8SIA4 9069
SEC24C 8993
SEC16B 8899
COPB2 8898
RPN2 8874
COPG2 8709
CMAS 8693
STX5 8547
DHDDS 8480
CSNK1D 8475
DDOST 8464
RENBP 8438
COG4 8402
ARF5 8313
DYNC1LI1 8276
COPE 8230
CAPZA2 8225
RNF185 8206
MIA2 8200
TFG 8124
TMED9 8028
F8 8026
ST6GALNAC2 8010
COPB1 7997
PMM1 7991
COL7A1 7971
ASGR1 7956
MGAT4B 7889
SEL1L 7883
VCP 7804
B4GALT1 7763
CALR 7713
SPTB 7702
GBF1 7683
DYNC1LI2 7644
YKT6 7621
DCTN6 7540
GMPPA 7523
NAPG 7516
SEC13 7506
MGAT1 7476
ARFGAP3 7424
SEC24B 7352
FPGT 7315
EDEM3 7305
RPN1 7151
SEC23A 7129
UGGT1 7118
ST8SIA5 7003
ARCN1 6965
SRD5A3 6925
SAR1B 6893
PRKCSH 6831
DYNC1I2 6705
NAPA 6660
DCTN3 6625
TRAPPC9 6548
FUCA1 6469
B4GALNT2 6427
KDELR2 6387
B4GALT4 6368
SCFD1 6297
AMFR 6296
SEC22B 6272
TMEM115 6183
UBC 6135
GOSR2 5986
ACTR10 5886
NUS1 5849
ALG12 5750
SYVN1 5702
ANK1 5655
TMED2 5345
MCFD2 5134
SLC35C1 5026
PSMC1 4827
SPTBN5 4732
ALG14 4622
TRAPPC3 4443
SEC31A 4346
MAGT1 4339
ARFGAP2 4331
SLC17A5 4301
CD59 4252
B4GALT6 4216
CNIH2 4186
PDIA3 4101
TSTA3 4081
SPTA1 4063
MGAT2 4055
TMED7 3978
TBC1D20 3947
PPP6R3 3723
DPM2 3619
FCSK 3513
ST6GALNAC4 3458
TMED3 3420
CANX 3332
TRAPPC5 3257
GANAB 3230
ST3GAL6 3223
NAPB 3180
MVD 3037
ARFGAP1 2978
STT3A 2891
DYNC1I1 2879
UBXN1 2648
GMPPB 2632
TRAPPC10 2565
USO1 2424
AREG 2386
COG5 2352
GMDS 2239
ST6GAL2 2226
PPP6C 2138
SLC35A1 2052
DAD1 1941
DYNC1H1 1705
LMAN2L 1586
DYNLL1 1530
MANEA 1515
TRAPPC6B 1327
UBB 1026
KDELR3 869
DOLK 844
MLEC 796
MARCHF6 740
SEC23IP 737
ALG1 491
COPZ1 412
COG8 406
TRIM13 367
DPM3 335
DCTN5 297
DERL2 50
RNF103 -101
SPTBN2 -220
RFT1 -227
ALG10 -316
NEU3 -511
MAN1B1 -683
ALG6 -798
NGLY1 -846
DPAGT1 -1022
NANP -1263
DPM1 -1376
BET1L -1574
DOLPP1 -1706
ALG2 -1755
B4GALT2 -1790
TRAPPC2L -1855
RNF139 -1918
MOGS -1931
EDEM1 -1934
COG3 -2175
TRAPPC4 -2490
CNIH1 -2698
ALG11 -2911
GOSR1 -3080
GNE -3093
SEC22C -3143
ALG13 -3317
AMDHD2 -3410
UBA52 -3490
MGAT4C -3553
CHST10 -3667
MIA3 -3686
RNF5 -3693
GFPT1 -3965
GOLGB1 -4004
MAN2A1 -4015
MAN1A2 -4146
TMED10 -4413
CNIH3 -4435
ALG3 -4562
ST8SIA6 -4572
FUOM -4628
PGM3 -4706
DYNLL2 -4904
NAGK -5108
ST3GAL5 -5223
ST3GAL3 -5250
FUT8 -5277
ALG8 -5338
ST6GALNAC6 -5407
ALG5 -5433
PMM2 -5443
MGAT5 -5546
COG2 -5554
NUDT14 -5651
ANKRD28 -5681
GFPT2 -5748
B4GALT3 -5794
ST3GAL1 -5904
COPZ2 -5974
MGAT3 -6227
BET1 -6342
DERL1 -6490
COG6 -6645
TRAPPC2 -7043
COG1 -7045
ALG9 -7052
MGAT4A -7072
ALG10B -7293
UAP1 -7325
ENGASE -7636
ANK3 -7751
SEC22A -7808
ST6GALNAC1 -7918
STX17 -8013
SPTBN1 -8138
LMAN1 -8522
ST6GAL1 -8538
MPI -8555
ST8SIA1 -9250
SPTAN1 -9461
TRAPPC6A -9543
RPS27A -9723
MAN1C1 -9944
GNPNAT1 -10125


Generic Transcription Pathway

Generic Transcription Pathway
444
set Generic Transcription Pathway
setSize 1077
pANOVA 5.38e-10
s.dist -0.112
p.adjustANOVA 1.56e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
RORC -10162
TCF7 -10143
CAMK4 -10131
NPM1 -10121
KIT -10114
GLS -10099
ZNF33B -10074
GATA3 -10071
NFYB -10059
LEF1 -10027
ZNF420 -10020
PMAIP1 -9993
WWP1 -9985
LRPPRC -9966
RGCC -9908
CAMK2D -9907
RAD1 -9896
ZNF530 -9862
ING5 -9861
ZNF136 -9839

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RORC -10162.0
TCF7 -10143.0
CAMK4 -10131.0
NPM1 -10121.0
KIT -10114.0
GLS -10099.0
ZNF33B -10074.0
GATA3 -10071.0
NFYB -10059.0
LEF1 -10027.0
ZNF420 -10020.0
PMAIP1 -9993.0
WWP1 -9985.0
LRPPRC -9966.0
RGCC -9908.0
CAMK2D -9907.0
RAD1 -9896.0
ZNF530 -9862.0
ING5 -9861.0
ZNF136 -9839.0
ANAPC1 -9829.0
NR3C2 -9803.0
RPA1 -9799.0
ZNF287 -9796.0
ZNF549 -9781.0
SUPT16H -9777.0
ZNF551 -9768.0
HSPD1 -9754.0
DYRK2 -9741.0
FOXO1 -9731.0
RPS27A -9723.0
ZIK1 -9720.0
FBXO32 -9702.0
ZNF302 -9688.0
ZNF566 -9650.0
ZNF208 -9592.0
ZNF337 -9551.0
RUNX2 -9531.0
NR1D2 -9530.0
ZNF711 -9525.0
ZNF485 -9524.0
WRN -9501.0
ZNF286A -9480.0
STAT1 -9448.0
SSRP1 -9439.0
ZNF138 -9435.0
PRKCQ -9424.0
CUL1 -9420.0
NR2C2AP -9415.0
RFC3 -9405.0
ZNF202 -9404.0
TNFRSF18 -9397.0
ZNF473 -9381.0
PERP -9367.0
MYC -9357.0
RBL2 -9335.0
ZNF681 -9332.0
ZNF517 -9328.0
FANCD2 -9324.0
ZNF548 -9316.0
ZNF30 -9308.0
ZNF599 -9307.0
ZNF567 -9273.0
GAMT -9258.0
ZFP28 -9238.0
RPA3 -9220.0
NR1D1 -9199.0
ZNF14 -9195.0
RORA -9193.0
ZNF354C -9174.0
TP53 -9170.0
CDK4 -9130.0
ZNF74 -9105.0
ZNF544 -9096.0
PCGF5 -9089.0
COX11 -9087.0
WWOX -9080.0
KAT2A -9063.0
ZNF331 -9055.0
ZNF696 -9045.0
ZNF354B -8996.0
CCND2 -8971.0
SCMH1 -8966.0
ZNF248 -8934.0
RFC4 -8897.0
CNOT7 -8894.0
CENPJ -8890.0
E2F6 -8869.0
ZNF583 -8867.0
ZNF540 -8856.0
AKT3 -8810.0
ZNF554 -8803.0
PLXNA4 -8763.0
TAF4B -8747.0
ZNF432 -8729.0
TGIF2 -8725.0
ZNF563 -8723.0
HDAC9 -8695.0
CTLA4 -8684.0
ZNF559 -8682.0
CDC23 -8677.0
GLI3 -8649.0
ZFP1 -8589.0
PHC1 -8578.0
ZNF431 -8542.0
GTF2H3 -8537.0
MED10 -8535.0
DGCR8 -8517.0
ZNF675 -8514.0
NFATC2 -8513.0
ZNF112 -8507.0
PSMB9 -8503.0
ZNF419 -8501.0
RAD17 -8493.0
ZNF43 -8456.0
JMY -8442.0
ZNF263 -8441.0
ZNF671 -8440.0
EPC1 -8428.0
TNKS1BP1 -8421.0
ZNF664 -8410.0
YEATS4 -8405.0
TFDP2 -8396.0
ZNF212 -8395.0
PARP1 -8391.0
PTPN4 -8389.0
PRMT1 -8388.0
ZNF568 -8387.0
RBBP7 -8382.0
ZNF773 -8360.0
L3MBTL2 -8356.0
BMI1 -8355.0
CNOT6L -8322.0
GPAM -8319.0
ZNF529 -8312.0
ZNF211 -8310.0
NOP2 -8307.0
FANCI -8301.0
ZNF749 -8279.0
ZNF253 -8261.0
KRBOX4 -8221.0
ZNF184 -8219.0
GTF2H1 -8203.0
DLL1 -8167.0
ZNF430 -8107.0
ZNF721 -8104.0
ZNF75A -8090.0
TAF9B -8058.0
ZNF461 -8022.0
ZNF180 -8011.0
GLS2 -8010.0
ATM -7980.0
ZNF383 -7970.0
ZNF740 -7969.0
ZNF793 -7943.0
ZNF235 -7939.0
TP53RK -7907.0
PPARD -7903.0
ZNF266 -7894.0
ZNF550 -7888.0
ZNF570 -7883.0
SMAD3 -7868.0
ZNF682 -7849.0
ZNF761 -7840.0
CASP6 -7832.0
ZNF446 -7827.0
ZNF416 -7817.0
ZNF300 -7805.0
MEAF6 -7803.0
PSME1 -7778.0
ESR2 -7755.0
ZNF23 -7752.0
ZNF571 -7750.0
SIN3A -7740.0
IGFBP3 -7733.0
ZNF678 -7727.0
ZNF519 -7686.0
TRIM28 -7684.0
IL2RA -7681.0
SMYD2 -7670.0
ITGA4 -7628.0
COX20 -7626.0
PCBP4 -7623.0
PRMT6 -7588.0
COX16 -7578.0
ZNF439 -7576.0
RFC5 -7574.0
ZNF582 -7563.0
SIRT1 -7544.0
ZNF480 -7534.0
ANAPC5 -7485.0
ZNF726 -7482.0
PSMA5 -7476.0
ZNF101 -7475.0
PPP1R13B -7472.0
ZNF792 -7466.0
RAD9A -7462.0
ZFP37 -7456.0
BRIP1 -7428.0
ZNF528 -7422.0
ZSCAN25 -7416.0
ACTL6A -7372.0
BCL2L14 -7358.0
ANAPC16 -7346.0
PSME2 -7327.0
KRBA1 -7316.0
TNRC6C -7302.0
ZNF514 -7289.0
ZNF727 -7257.0
NR2C1 -7255.0
ZNF226 -7240.0
FASLG -7230.0
ZFP2 -7226.0
MDC1 -7222.0
ZNF483 -7220.0
ZNF649 -7212.0
MSH2 -7130.0
MAML2 -7122.0
ZNF257 -7118.0
PCNA -7101.0
RBL1 -7071.0
ZNF141 -7054.0
ZNF597 -7046.0
ZNF343 -7036.0
RABGGTB -7020.0
ZNF737 -6994.0
ZNF662 -6969.0
CCNC -6937.0
TGIF1 -6918.0
ZNF706 -6913.0
ZNF10 -6889.0
HDAC2 -6871.0
ZNF140 -6857.0
POLR2D -6856.0
ZNF157 -6825.0
EED -6816.0
ZNF707 -6802.0
ZNF614 -6794.0
PRR5 -6787.0
ZNF3 -6744.0
RUNX3 -6737.0
ZNF616 -6716.0
MED6 -6714.0
E2F5 -6685.0
MRE11 -6668.0
CBX5 -6643.0
ZNF470 -6614.0
ZNF26 -6613.0
KMT2A -6588.0
ZNF708 -6581.0
ZNF736 -6571.0
RHNO1 -6539.0
CHD3 -6523.0
UXT -6504.0
GATA2 -6470.0
CCNG1 -6462.0
TCEA1 -6441.0
PSMA3 -6433.0
ZNF17 -6429.0
ZNF606 -6404.0
SRC -6396.0
ZFP69 -6391.0
ZNF680 -6386.0
ZNF677 -6358.0
MNAT1 -6327.0
DNA2 -6307.0
SKP1 -6297.0
ZFP90 -6295.0
ZKSCAN8 -6292.0
ZNF771 -6283.0
ZNF799 -6276.0
SGK1 -6264.0
MAPKAPK5 -6258.0
ZNF738 -6246.0
ZNF506 -6235.0
POLR2H -6200.0
ZNF135 -6198.0
PIP4K2B -6196.0
ZNF584 -6175.0
CHEK1 -6143.0
ERBB2 -6142.0
PIDD1 -6109.0
BTG1 -6108.0
ZNF12 -6071.0
ZNF274 -6041.0
TRIAP1 -6036.0
MEF2C -6025.0
ZNF510 -6017.0
ZNF415 -6008.0
ZNF175 -5991.0
ZNF154 -5972.0
ZNF317 -5967.0
ZNF496 -5965.0
BRD1 -5958.0
MOV10 -5956.0
MBD3 -5950.0
ZNF772 -5933.0
SETD1A -5910.0
PVALB -5879.0
TAF5 -5865.0
SMURF2 -5858.0
ZNF790 -5845.0
ZNF782 -5838.0
ZNF285 -5804.0
MGA -5799.0
ZNF234 -5788.0
TBP -5776.0
PPP1R13L -5769.0
ZFP30 -5763.0
ZNF777 -5753.0
ZNF224 -5735.0
H2BC9 -5728.0
RAD51D -5721.0
SCO1 -5653.0
SESN1 -5650.0
ZNF223 -5631.0
ZNF786 -5630.0
ZNF600 -5624.0
RBBP4 -5599.0
H2AZ2 -5576.0
MAF -5558.0
ZNF596 -5548.0
PRKAB2 -5520.0
TAF3 -5461.0
ZNF577 -5437.0
FOXP3 -5412.0
BTG2 -5374.0
ZNF273 -5371.0
MEN1 -5364.0
SMARCD1 -5357.0
ATR -5340.0
SUZ12 -5320.0
COX14 -5300.0
E2F7 -5283.0
RICTOR -5264.0
COX6C -5236.0
PHF20 -5199.0
PPP2R5C -5198.0
TCF3 -5184.0
ZNF92 -5177.0
MT-CO3 -5157.0
BLM -5151.0
YY1 -5142.0
TAF9 -5099.0
TRPC3 -5092.0
ZNF33A -5085.0
ZNF133 -5063.0
TXNIP -5058.0
ZNF417 -5015.0
AUTS2 -4988.0
ZNF569 -4986.0
SESN3 -4984.0
ZNF607 -4976.0
MAMLD1 -4969.0
ZNF493 -4959.0
ZNF709 -4926.0
ZNF692 -4918.0
POLR2K -4907.0
ZSCAN32 -4901.0
ZNF860 -4892.0
COX19 -4881.0
ZNF227 -4873.0
NELFCD -4863.0
TP73 -4859.0
TAF15 -4857.0
ZNF658 -4856.0
ZNF605 -4845.0
CDK6 -4840.0
LDB1 -4826.0
ZNF573 -4817.0
RPA2 -4811.0
ZNF334 -4743.0
ZNF620 -4741.0
COX7C -4688.0
TTC5 -4664.0
ZNF785 -4652.0
MAPK11 -4641.0
AIFM2 -4640.0
YWHAQ -4624.0
ZNF626 -4612.0
SETD9 -4610.0
ZNF2 -4566.0
ZNF433 -4558.0
PSMC5 -4553.0
ZNF268 -4552.0
VENTX -4549.0
ATAD2 -4527.0
ZFP14 -4515.0
ZNF767P -4494.0
CDC7 -4493.0
MYB -4488.0
ZFPM1 -4486.0
CYCS -4456.0
ZNF233 -4440.0
ZNF585B -4432.0
ZNF500 -4424.0
ZNF492 -4394.0
SMARCC1 -4387.0
COX18 -4373.0
BLK -4300.0
YAF2 -4258.0
THRB -4237.0
ZNF543 -4233.0
ZNF70 -4218.0
ZNF441 -4195.0
ZNF75D -4153.0
PMS2 -4151.0
ZNF440 -4147.0
ZNF37A -4117.0
CDC16 -4089.0
PSMB10 -4050.0
PRDX2 -4039.0
ZNF425 -4008.0
ZNF625 -3979.0
CREB1 -3977.0
PRDM1 -3968.0
SKI -3963.0
ZNF484 -3957.0
POLR2I -3929.0
ZNF45 -3920.0
ZNF688 -3901.0
CCNT1 -3880.0
ZNF621 -3874.0
ANAPC2 -3830.0
SCO2 -3829.0
CCND1 -3813.0
CTSV -3775.0
EZH2 -3766.0
H19 -3763.0
NR2F6 -3738.0
RING1 -3707.0
CCNE1 -3688.0
ZNF703 -3683.0
RARG -3682.0
SUPT5H -3672.0
ZNF382 -3661.0
MECP2 -3660.0
SMAD4 -3639.0
PAX5 -3632.0
CDK2 -3614.0
PSMB1 -3610.0
ATRIP -3603.0
ZNF19 -3587.0
RAD51 -3583.0
ZNF610 -3580.0
UBA52 -3490.0
ZNF324 -3489.0
ZNF250 -3486.0
ZNF521 -3453.0
ZNF670 -3401.0
DEK -3397.0
POLR2B -3384.0
ZNF546 -3301.0
TACO1 -3299.0
ZNF486 -3296.0
ZNF714 -3288.0
ZNF564 -3260.0
RAD50 -3254.0
ZNF324B -3252.0
ZNF689 -3229.0
ZNF595 -3227.0
SMARCE1 -3212.0
CDKN1B -3127.0
ESR1 -3021.0
SOCS4 -2988.0
AXIN1 -2986.0
UBE2E1 -2985.0
MED27 -2978.0
CBX2 -2958.0
ZNF557 -2919.0
EXO1 -2916.0
YES1 -2846.0
MED30 -2845.0
PSMA2 -2823.0
NELFA -2822.0
TNFRSF10A -2801.0
ZNF561 -2797.0
ZNF418 -2796.0
PSMA4 -2764.0
ZNF77 -2710.0
ANAPC4 -2692.0
STUB1 -2688.0
SMARCB1 -2683.0
CNOT10 -2678.0
NR4A1 -2672.0
EHMT2 -2671.0
RRAGB -2658.0
MED17 -2648.0
CDK1 -2593.0
ZNF558 -2569.0
CNOT2 -2544.0
MT-CO2 -2523.0
PSMD10 -2515.0
MED31 -2514.0
RRM2 -2442.0
PHC3 -2377.0
UBE2I -2356.0
NUAK1 -2339.0
SIRT3 -2325.0
MED4 -2264.0
WDR5 -2237.0
ZNF791 -2198.0
DAXX -2153.0
PF4 -2122.0
ZNF264 -2113.0
ZNF585A -2053.0
THRA -2010.0
ZNF169 -1961.0
NR4A3 -1943.0
ZNF160 -1941.0
BRD7 -1932.0
PRKAG2 -1916.0
ZNF436 -1909.0
SKP2 -1895.0
CLDN5 -1869.0
ANAPC10 -1816.0
ZNF724 -1814.0
PPARGC1A -1762.0
CDC26 -1744.0
ZNF720 -1737.0
ING2 -1723.0
NR2C2 -1712.0
GTF2H5 -1698.0
ZNF717 -1691.0
ZNF684 -1667.0
ZNF624 -1616.0
BBC3 -1611.0
ZNF665 -1605.0
ZNF221 -1593.0
ZNF41 -1570.0
L3MBTL1 -1539.0
ZNF676 -1527.0
RBM14 -1512.0
NR4A2 -1447.0
FBXW7 -1315.0
ZNF100 -1250.0
CALM1 -1245.0
ZNF565 -1174.0
ZNF34 -1172.0
MYBL2 -1171.0
RPTOR -1137.0
ZNF547 -1122.0
ZNF667 -1090.0
PCGF6 -1085.0
RBBP5 -1075.0
ZNF426 -1066.0
MLST8 -1064.0
DDB2 -1024.0
NOC2L -998.0
ZNF99 -982.0
MED1 -971.0
IFNG -958.0
TMEM219 -957.0
ZNF197 -922.0
MED15 -911.0
TFAP2E -902.0
CHEK2 -865.0
ZNF195 -841.0
PML -815.0
GTF2H4 -803.0
ZNF71 -753.0
ATXN3 -673.0
ZNF589 -659.0
ATF2 -657.0
ZNF713 -656.0
CCNT2 -632.0
ZNF700 -598.0
POLR2C -494.0
TRIM33 -473.0
FANCC -455.0
MT-CO1 -454.0
PSMB8 -438.0
ZNF615 -407.0
DPY30 -319.0
TAF1 -304.0
TJP1 -300.0
COX4I1 -286.0
RMI2 -282.0
ZNF770 -273.0
ELF1 -271.0
STK11 -238.0
BRD2 -209.0
RELA -204.0
ZNF627 -194.0
PCGF2 -177.0
MAX -145.0
RNF34 -115.0
PPARGC1B -31.0
CDKN2A 48.0
SMAD7 52.0
PPP2R1B 89.0
TAF11 95.0
BGLAP 197.0
HDAC6 243.0
RNF2 248.0
CDC27 283.0
CHD4 290.0
H2BU1 298.0
TNRC6B 301.0
OCLN 304.0
TNRC6A 318.0
PIP4K2A 379.0
TOPBP1 397.0
ZNF350 404.0
OPRM1 433.0
ANAPC7 498.0
CBFB 503.0
ZNF155 509.0
KMT2E 515.0
ZNF655 517.0
PLK2 549.0
PIN1 577.0
ARID1B 588.0
PSMC4 605.0
ZNF222 626.0
MED13 630.0
PSMB4 642.0
HDAC1 650.0
ZNF699 661.0
ZNF442 703.0
ZNF764 733.0
CCNB1 735.0
ZNF747 780.0
TAF6 791.0
ZNF398 863.0
GAD2 875.0
E2F8 895.0
PSMC3 916.0
PSMD14 941.0
NR1H3 954.0
CITED4 960.0
ZNF562 990.0
CASP10 1005.0
NR3C1 1021.0
UBB 1026.0
ZNF189 1034.0
KLF4 1084.0
CHM 1115.0
PIP4K2C 1118.0
ZNF716 1137.0
MED7 1178.0
MED24 1185.0
MLH1 1189.0
BRPF3 1249.0
FAS 1260.0
ZNF200 1270.0
ZNF124 1333.0
MDM4 1356.0
CDK5R1 1363.0
PRELID3A 1364.0
ZNF619 1399.0
TSC1 1403.0
ZNF443 1414.0
CNOT11 1459.0
TAF4 1471.0
NBN 1482.0
PRMT5 1582.0
ZNF641 1585.0
ZNF776 1623.0
ZNF750 1680.0
ZNF778 1729.0
ZKSCAN4 1738.0
RRAGC 1745.0
PSMB2 1760.0
MTOR 1777.0
ZKSCAN3 1789.0
NELFB 1812.0
PSME4 1818.0
SFN 1840.0
SMARCA2 1856.0
CCNA2 1863.0
MED23 1915.0
MYL9 1931.0
AURKB 1985.0
POLR2L 2016.0
CASP2 2017.0
ZNF660 2023.0
CCNH 2048.0
KAT2B 2054.0
SIN3B 2071.0
PSMD7 2084.0
RABGGTA 2092.0
BRPF1 2098.0
CDK13 2118.0
ZNF691 2191.0
CAV1 2229.0
AGRP 2238.0
SREBF1 2292.0
ZNF658B 2299.0
CBX3 2333.0
ZNF669 2359.0
TCF12 2381.0
PRKAA1 2409.0
HDAC10 2431.0
APOE 2448.0
H2BC15 2474.0
CAMK2G 2528.0
GPS2 2541.0
AGO3 2552.0
ZNF587 2582.0
CBX8 2624.0
ZNF429 2657.0
HIVEP3 2666.0
ZNF79 2726.0
ZNF556 2729.0
CNOT8 2767.0
FOS 2787.0
RXRB 2848.0
NFKB1 2860.0
MTA2 2877.0
CASP1 2896.0
BANP 2945.0
CNOT4 3043.0
ZNF25 3085.0
RRM2B 3109.0
TAF2 3110.0
PSMA1 3111.0
JUN 3122.0
TAL1 3132.0
EHMT1 3155.0
COX5A 3171.0
TAF7 3179.0
SUPT4H1 3268.0
ZNF668 3291.0
GTF2H2 3309.0
ZNF320 3311.0
GCK 3322.0
SNW1 3347.0
SURF1 3355.0
GPX2 3367.0
HDAC5 3369.0
ERCC3 3424.0
RFFL 3429.0
SEM1 3454.0
CRADD 3517.0
UBE2C 3555.0
KAT5 3557.0
CCNE2 3568.0
ZKSCAN1 3585.0
ARID2 3609.0
ZNF555 3636.0
MOBP 3646.0
ITGAL 3647.0
ZNF611 3658.0
ELOA 3736.0
PSMD13 3766.0
TCF7L1 3775.0
ZNF394 3785.0
PRDX1 3802.0
POMC 3862.0
ANAPC11 3904.0
ZNF347 3913.0
NPPA 3921.0
RBX1 3957.0
FZR1 3967.0
COX7A2L 3979.0
SUMO1 4061.0
GP1BA 4136.0
ZNF215 4137.0
DDIT4 4138.0
CDK7 4155.0
MED16 4162.0
POLR2G 4175.0
ZNF701 4187.0
ZNF839 4197.0
HUS1 4236.0
CNOT1 4249.0
BARD1 4253.0
POLR2F 4256.0
PSMF1 4259.0
PSMD3 4297.0
TSC2 4311.0
CDK8 4340.0
H2AZ1 4378.0
TPX2 4403.0
NDUFA4 4421.0
RHEB 4425.0
COX7B 4513.0
BIRC5 4541.0
PSMC2 4543.0
KAT6A 4584.0
MAPKAP1 4588.0
THBS1 4645.0
ZNF718 4650.0
BNIP3L 4710.0
YWHAB 4721.0
UBE2S 4773.0
PSMC1 4827.0
TBL1XR1 4852.0
ZNF471 4855.0
PPARA 4862.0
ZNF586 4863.0
ZNF20 4882.0
ZFP69B 4901.0
ZNF490 4930.0
PSMC6 4959.0
ZNF205 4960.0
ZNF385A 5003.0
SERPINE1 5005.0
COX5B 5048.0
GPRIN1 5069.0
POLR2E 5109.0
ZNF775 5111.0
PPP2R1A 5189.0
YWHAZ 5202.0
PSMA6 5209.0
E2F4 5213.0
CBX6 5259.0
CTSK 5320.0
LAMTOR3 5383.0
KCTD6 5411.0
HDAC3 5437.0
H2AC6 5440.0
BAX 5446.0
HDAC11 5471.0
RFC2 5478.0
SLC38A9 5485.0
TEAD2 5487.0
AKT2 5502.0
TGFB1 5504.0
ZNF460 5515.0
CDKN1A 5537.0
POLR2J 5598.0
MED14 5610.0
CDK9 5620.0
VEGFA 5648.0
PSMD8 5687.0
KCTD1 5799.0
CDC25C 5800.0
ZNF613 5823.0
ZNF354A 5856.0
SMARCC2 5869.0
CSNK2B 5876.0
COX6A1 5884.0
WWTR1 5902.0
CDK12 5907.0
PBRM1 5917.0
NR1I3 5969.0
GATAD2B 5985.0
LAMTOR4 6002.0
MDM2 6043.0
AGO2 6087.0
H2BC11 6121.0
ABL1 6127.0
KRAS 6132.0
UBC 6135.0
ZNF697 6137.0
ZNF702P 6149.0
H2BC17 6188.0
HDAC8 6235.0
GTF2F2 6257.0
USP7 6259.0
SMAD2 6291.0
USP9X 6344.0
RBBP8 6377.0
KMT2C 6410.0
DDIT3 6480.0
SMURF1 6481.0
AKT1 6498.0
ZFHX3 6518.0
PTPN11 6524.0
MED26 6537.0
TIGAR 6589.0
RAD9B 6597.0
RYBP 6609.0
ERCC2 6621.0
AR 6643.0
NFYA 6667.0
AURKA 6693.0
NELFE 6710.0
ZNF774 6717.0
GTF2F1 6738.0
ITCH 6755.0
H2BC5 6759.0
PPP2CA 6806.0
E2F1 6818.0
PSMD12 6820.0
SKIL 6851.0
TP53INP1 6853.0
PLK3 6889.0
GATAD2A 6890.0
ZKSCAN7 6896.0
TNFRSF10D 6912.0
ELOC 6974.0
CCNA1 7002.0
RNF111 7005.0
BRCA1 7032.0
G6PC 7036.0
PRELID1 7109.0
GPI 7117.0
GSK3B 7147.0
PRKAB1 7148.0
CNOT6 7242.0
JUNB 7257.0
SOD2 7284.0
PSMD6 7307.0
CSNK2A2 7341.0
ITGA2B 7387.0
HDAC7 7388.0
PSMB6 7399.0
NRBP1 7428.0
ELOB 7435.0
CBX4 7438.0
PPP2CB 7451.0
ELF2 7487.0
ABCA6 7495.0
PLAGL1 7496.0
HES1 7535.0
BID 7544.0
PPM1D 7552.0
SETD1B 7555.0
PSMD5 7646.0
KCTD15 7676.0
SMARCD3 7698.0
MED12 7718.0
TBL1X 7764.0
PSMD11 7775.0
PRKAG1 7805.0
PSMA7 7840.0
POLR2A 7852.0
ZKSCAN5 7864.0
SMARCA4 7879.0
KMT2B 7908.0
IRAK1 7970.0
PSMB3 8005.0
LAMTOR2 8006.0
COX6B1 8031.0
CCNK 8038.0
ZNF552 8044.0
COX8A 8092.0
MED25 8136.0
PSMD2 8139.0
CREBBP 8143.0
NCOR1 8153.0
PSMD1 8184.0
ELL 8187.0
ZNF333 8189.0
ZNF267 8220.0
JAG1 8240.0
RRAGD 8243.0
ZNF18 8255.0
PSMB5 8265.0
ANAPC15 8323.0
SMARCD2 8363.0
NOTCH2 8400.0
PSMB7 8460.0
CITED2 8503.0
HIPK1 8544.0
CNOT3 8550.0
PRKCB 8577.0
UBE2D3 8641.0
MED8 8643.0
ZNF468 8676.0
TFDP1 8682.0
PDPK1 8710.0
PSME3 8716.0
TAF13 8718.0
ZNF282 8738.0
MED20 8757.0
PSMD9 8766.0
AGO1 8810.0
APAF1 8822.0
LBR 8834.0
TAF12 8850.0
ASH2L 8855.0
KMT2D 8863.0
LAMTOR5 8889.0
H2AC20 8893.0
ZNF28 8904.0
PPM1A 8912.0
H2BC4 8925.0
H3C15 8929.5
CDKN2B 8931.0
TNFRSF10B 8944.0
ZNF230 8954.0
YWHAE 8971.0
H3-3A 8985.0
NR6A1 9008.0
RMI1 9032.0
RRAGA 9038.0
CSNK2A1 9040.0
NRBF2 9084.0
NEDD4L 9088.0
TP53BP2 9121.0
TNFRSF10C 9127.0
BCL2L11 9144.0
LGALS3 9180.0
ESRRA 9192.0
FOXO4 9205.0
ZNF445 9223.0
SATB2 9256.0
LAMTOR1 9265.0
PRDX5 9267.0
TXN 9268.0
H2BC12 9280.0
UBE2D1 9286.0
CTDP1 9289.0
CCNG2 9366.0
KDM5B 9406.0
TAF10 9419.0
NOTCH1 9499.0
NR1H2 9521.0
GATA1 9542.0
PTEN 9545.0
ARID1A 9567.0
CSF1R 9627.0
ZNF213 9638.0
CTNNB1 9670.0
HTT 9679.0
TOP3A 9684.0
H2BC21 9690.0
SP1 9699.0
MAPK3 9750.0
SESN2 9768.0
LMO2 9776.0
STEAP3 9786.0
EP300 9789.0
FOXO3 9800.0
RB1 9839.0
ITGA5 9848.0
TXNRD1 9890.0
NDRG1 10027.0
MAML1 10046.0
YWHAH 10050.0
HIPK2 10064.0
RXRA 10073.0
DLX6 10075.0
ARID3A 10084.0
PSMD4 10088.0
CAT 10103.0
RBPJ 10176.0
ZNF746 10212.0
CTSL 10288.0
NOTCH4 10293.0
CARM1 10313.0
TWIST2 10353.0
YWHAG 10453.0
KMT5A 10459.0
NFYC 10461.0
CCND3 10476.0
RUNX1 10531.0
PINK1 10533.0
AGO4 10537.0
ZNF710 10617.0
PTPN1 10623.0
CDK5 10628.0
MAML3 10651.0
SLC2A3 10714.0
RETN 10732.0
TCF7L2 10773.0
RARA 10808.0
SMAD6 10809.0
SOCS3 10826.0
HDAC4 10884.0
G6PD 10948.0
MAP2K6 10958.0
FKBP5 10974.0
TGFA 10983.0
GSR 11051.0
GADD45A 11089.0
MAPK14 11115.0
CEBPB 11136.0
PHC2 11145.0
MAPK1 11193.0
NCOR2 11217.0
SPI1 11223.0
NLRC4 11239.0
NFE2 11293.0
BCL6 11324.0
PRKACA 11363.0
VDR 11370.0
CR1 11401.0
SMAD1 11403.0
NOTCH3 11420.0
TP53I3 11439.0
H2AJ 11447.0
PPARG 11451.0


RNA Polymerase II Transcription

RNA Polymerase II Transcription
907
set RNA Polymerase II Transcription
setSize 1196
pANOVA 7.42e-10
s.dist -0.106
p.adjustANOVA 2.1e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
RORC -10162
TCF7 -10143
CAMK4 -10131
NPM1 -10121
KIT -10114
GLS -10099
ZNF33B -10074
GATA3 -10071
NFYB -10059
LEF1 -10027
ZNF420 -10020
PMAIP1 -9993
WWP1 -9985
LRPPRC -9966
ZC3H8 -9937
RGCC -9908
CAMK2D -9907
RAD1 -9896
ZNF530 -9862
ING5 -9861

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RORC -10162.0
TCF7 -10143.0
CAMK4 -10131.0
NPM1 -10121.0
KIT -10114.0
GLS -10099.0
ZNF33B -10074.0
GATA3 -10071.0
NFYB -10059.0
LEF1 -10027.0
ZNF420 -10020.0
PMAIP1 -9993.0
WWP1 -9985.0
LRPPRC -9966.0
ZC3H8 -9937.0
RGCC -9908.0
CAMK2D -9907.0
RAD1 -9896.0
ZNF530 -9862.0
ING5 -9861.0
ZNF136 -9839.0
ANAPC1 -9829.0
NR3C2 -9803.0
RPA1 -9799.0
ZNF287 -9796.0
ZNF549 -9781.0
SUPT16H -9777.0
THOC3 -9772.0
ZNF551 -9768.0
HSPD1 -9754.0
DYRK2 -9741.0
FOXO1 -9731.0
RPS27A -9723.0
ZIK1 -9720.0
FBXO32 -9702.0
ZNF302 -9688.0
MLLT3 -9657.0
ZNF566 -9650.0
NCBP2 -9631.0
ZNF208 -9592.0
ZNF337 -9551.0
RUNX2 -9531.0
NR1D2 -9530.0
ZNF711 -9525.0
ZNF485 -9524.0
WRN -9501.0
ZNF286A -9480.0
STAT1 -9448.0
SSRP1 -9439.0
ZNF138 -9435.0
PRKCQ -9424.0
CUL1 -9420.0
NR2C2AP -9415.0
RFC3 -9405.0
ZNF202 -9404.0
TNFRSF18 -9397.0
ZNF473 -9381.0
PERP -9367.0
MYC -9357.0
RBL2 -9335.0
ZNF681 -9332.0
ZNF517 -9328.0
FANCD2 -9324.0
ZNF548 -9316.0
ZNF30 -9308.0
ZNF599 -9307.0
SRSF5 -9275.0
ZNF567 -9273.0
GAMT -9258.0
ZFP28 -9238.0
RPA3 -9220.0
NR1D1 -9199.0
ZNF14 -9195.0
RORA -9193.0
ZNF354C -9174.0
TP53 -9170.0
CDK4 -9130.0
ZNF74 -9105.0
ZNF544 -9096.0
PCGF5 -9089.0
COX11 -9087.0
LSM11 -9085.0
WWOX -9080.0
KAT2A -9063.0
ZNF331 -9055.0
ZNF696 -9045.0
SRSF11 -9002.0
ZNF354B -8996.0
CCND2 -8971.0
SCMH1 -8966.0
ZNF248 -8934.0
RFC4 -8897.0
CNOT7 -8894.0
CENPJ -8890.0
E2F6 -8869.0
ZNF583 -8867.0
ZNF540 -8856.0
AKT3 -8810.0
ZNF554 -8803.0
PLXNA4 -8763.0
TAF4B -8747.0
ZNF432 -8729.0
TGIF2 -8725.0
ZNF563 -8723.0
HDAC9 -8695.0
SNRPF -8687.0
CTLA4 -8684.0
ZNF559 -8682.0
CDC23 -8677.0
GLI3 -8649.0
ZFP1 -8589.0
PHC1 -8578.0
SRSF6 -8576.0
SNRPE -8564.0
ZNF431 -8542.0
GTF2H3 -8537.0
MED10 -8535.0
DGCR8 -8517.0
ZNF675 -8514.0
NFATC2 -8513.0
ZNF112 -8507.0
PSMB9 -8503.0
ZNF419 -8501.0
RAD17 -8493.0
ZNF43 -8456.0
JMY -8442.0
ZNF263 -8441.0
ZNF671 -8440.0
EPC1 -8428.0
TNKS1BP1 -8421.0
ZNF664 -8410.0
YEATS4 -8405.0
TFDP2 -8396.0
ZNF212 -8395.0
PARP1 -8391.0
PTPN4 -8389.0
PRMT1 -8388.0
ZNF568 -8387.0
RBBP7 -8382.0
ZNF773 -8360.0
L3MBTL2 -8356.0
BMI1 -8355.0
CNOT6L -8322.0
GPAM -8319.0
ZNF529 -8312.0
ZNF211 -8310.0
NOP2 -8307.0
FANCI -8301.0
ZNF749 -8279.0
ZNF253 -8261.0
KRBOX4 -8221.0
ZNF184 -8219.0
GTF2H1 -8203.0
DLL1 -8167.0
PHAX -8164.0
ZNF430 -8107.0
ZNF721 -8104.0
ZNF75A -8090.0
TAF9B -8058.0
RNPS1 -8030.0
ZNF461 -8022.0
ZNF180 -8011.0
GLS2 -8010.0
ATM -7980.0
ZNF383 -7970.0
ZNF740 -7969.0
ICE2 -7963.0
THOC1 -7949.0
ZNF793 -7943.0
ZNF235 -7939.0
TP53RK -7907.0
PPARD -7903.0
ZNF266 -7894.0
ZNF550 -7888.0
ZNF570 -7883.0
SMAD3 -7868.0
ZNF682 -7849.0
ZNF761 -7840.0
CASP6 -7832.0
ZNF446 -7827.0
ZNF416 -7817.0
ZNF300 -7805.0
MEAF6 -7803.0
NUDT21 -7791.0
PSME1 -7778.0
ESR2 -7755.0
ZNF23 -7752.0
ZNF571 -7750.0
SIN3A -7740.0
IGFBP3 -7733.0
ZNF678 -7727.0
ZNF519 -7686.0
TRIM28 -7684.0
IL2RA -7681.0
SMYD2 -7670.0
ITGA4 -7628.0
COX20 -7626.0
PCBP4 -7623.0
PRMT6 -7588.0
COX16 -7578.0
ZNF439 -7576.0
RFC5 -7574.0
RNMT -7569.0
ZNF582 -7563.0
SIRT1 -7544.0
ZNF480 -7534.0
ANAPC5 -7485.0
ZNF726 -7482.0
PSMA5 -7476.0
ZNF101 -7475.0
PPP1R13B -7472.0
ZNF792 -7466.0
RAD9A -7462.0
ZFP37 -7456.0
BRIP1 -7428.0
ZNF528 -7422.0
ZSCAN25 -7416.0
ACTL6A -7372.0
BCL2L14 -7358.0
ANAPC16 -7346.0
PSME2 -7327.0
KRBA1 -7316.0
TNRC6C -7302.0
ZNF514 -7289.0
CSTF1 -7266.0
ZNF727 -7257.0
NR2C1 -7255.0
ZNF226 -7240.0
FASLG -7230.0
SRSF7 -7229.0
ZFP2 -7226.0
MDC1 -7222.0
ZNF483 -7220.0
ZNF649 -7212.0
MSH2 -7130.0
MAML2 -7122.0
ZNF257 -7118.0
PCNA -7101.0
RBL1 -7071.0
ZNF141 -7054.0
ZNF597 -7046.0
ZNF343 -7036.0
RABGGTB -7020.0
ZNF737 -6994.0
ZNF662 -6969.0
CCNC -6937.0
TGIF1 -6918.0
ZNF706 -6913.0
ZNF10 -6889.0
HDAC2 -6871.0
ZNF140 -6857.0
POLR2D -6856.0
ZNF157 -6825.0
EED -6816.0
ZNF707 -6802.0
ZNF614 -6794.0
PRR5 -6787.0
ZNF3 -6744.0
RUNX3 -6737.0
MAGOHB -6726.0
ZNF616 -6716.0
MED6 -6714.0
E2F5 -6685.0
MRE11 -6668.0
FYTTD1 -6647.0
CBX5 -6643.0
ZNF470 -6614.0
ZNF26 -6613.0
KMT2A -6588.0
ZNF708 -6581.0
ZNF736 -6571.0
RHNO1 -6539.0
CHD3 -6523.0
UXT -6504.0
GATA2 -6470.0
CCNG1 -6462.0
TCEA1 -6441.0
PSMA3 -6433.0
ZNF17 -6429.0
ZNF606 -6404.0
SRC -6396.0
ZFP69 -6391.0
ZNF680 -6386.0
ZNF677 -6358.0
SNRPD3 -6352.0
MNAT1 -6327.0
DNA2 -6307.0
SKP1 -6297.0
ZFP90 -6295.0
ZKSCAN8 -6292.0
ZNF771 -6283.0
ZNF799 -6276.0
SGK1 -6264.0
MAPKAPK5 -6258.0
ZNF738 -6246.0
ZNF506 -6235.0
POLR2H -6200.0
ZNF135 -6198.0
PIP4K2B -6196.0
SRSF2 -6188.0
ZNF584 -6175.0
CHEK1 -6143.0
ERBB2 -6142.0
PIDD1 -6109.0
BTG1 -6108.0
ZNF12 -6071.0
ZNF274 -6041.0
TRIAP1 -6036.0
MEF2C -6025.0
ZNF510 -6017.0
ZNF415 -6008.0
ZNF175 -5991.0
ZNF154 -5972.0
ZNF317 -5967.0
ZNF496 -5965.0
BRD1 -5958.0
MOV10 -5956.0
MBD3 -5950.0
ZNF772 -5933.0
SETD1A -5910.0
PVALB -5879.0
TAF5 -5865.0
SMURF2 -5858.0
ZNF790 -5845.0
UPF3B -5843.0
ZNF782 -5838.0
ZNF285 -5804.0
INTS5 -5803.0
MGA -5799.0
ZNF234 -5788.0
TBP -5776.0
PPP1R13L -5769.0
ZFP30 -5763.0
ZNF777 -5753.0
ZNF224 -5735.0
H2BC9 -5728.0
RAD51D -5721.0
SRRT -5701.0
SCO1 -5653.0
SESN1 -5650.0
ZNF223 -5631.0
ZNF786 -5630.0
ZNF600 -5624.0
RBBP4 -5599.0
H2AZ2 -5576.0
MAF -5558.0
SRSF3 -5550.0
ZNF596 -5548.0
PRKAB2 -5520.0
TAF3 -5461.0
ZNF577 -5437.0
FOXP3 -5412.0
BTG2 -5374.0
ZNF273 -5371.0
MEN1 -5364.0
SMARCD1 -5357.0
ATR -5340.0
SUZ12 -5320.0
COX14 -5300.0
E2F7 -5283.0
RICTOR -5264.0
COX6C -5236.0
PHF20 -5199.0
PPP2R5C -5198.0
TCF3 -5184.0
ZNF92 -5177.0
MT-CO3 -5157.0
BLM -5151.0
YY1 -5142.0
TAF9 -5099.0
TRPC3 -5092.0
ZNF33A -5085.0
ZNF133 -5063.0
TXNIP -5058.0
ZNF417 -5015.0
AUTS2 -4988.0
ZNF569 -4986.0
SESN3 -4984.0
ZNF607 -4976.0
MAMLD1 -4969.0
ZNF493 -4959.0
ZNF709 -4926.0
ZNF692 -4918.0
POLR2K -4907.0
ZSCAN32 -4901.0
ZNF860 -4892.0
COX19 -4881.0
ZNF227 -4873.0
NELFCD -4863.0
TP73 -4859.0
TAF15 -4857.0
ZNF658 -4856.0
ZNF605 -4845.0
CDK6 -4840.0
LDB1 -4826.0
ZNF573 -4817.0
RPA2 -4811.0
ZNF334 -4743.0
ZNF620 -4741.0
ICE1 -4727.0
COX7C -4688.0
MAGOH -4678.0
TTC5 -4664.0
ZNF785 -4652.0
SNAPC1 -4648.0
MAPK11 -4641.0
AIFM2 -4640.0
YWHAQ -4624.0
ZNF626 -4612.0
SETD9 -4610.0
ZNF2 -4566.0
ZNF433 -4558.0
PSMC5 -4553.0
ZNF268 -4552.0
VENTX -4549.0
ATAD2 -4527.0
ZFP14 -4515.0
ZNF767P -4494.0
CDC7 -4493.0
MYB -4488.0
ZFPM1 -4486.0
INTS4 -4485.0
CYCS -4456.0
ZNF233 -4440.0
ZNF585B -4432.0
ZNF500 -4424.0
ZNF492 -4394.0
SMARCC1 -4387.0
COX18 -4373.0
BLK -4300.0
YAF2 -4258.0
THRB -4237.0
ZNF543 -4233.0
ZNF70 -4218.0
ZNF441 -4195.0
SNRPB -4187.0
ZNF75D -4153.0
PMS2 -4151.0
ZNF440 -4147.0
ZNF37A -4117.0
CDC16 -4089.0
PSMB10 -4050.0
PRDX2 -4039.0
CPSF4 -4025.0
ZNF425 -4008.0
ZNF625 -3979.0
CREB1 -3977.0
PRDM1 -3968.0
SKI -3963.0
ZNF484 -3957.0
POLR2I -3929.0
ZNF45 -3920.0
ZNF688 -3901.0
CCNT1 -3880.0
ZNF621 -3874.0
ANAPC2 -3830.0
SCO2 -3829.0
CCND1 -3813.0
CTSV -3775.0
EZH2 -3766.0
H19 -3763.0
DDX39A -3754.0
NR2F6 -3738.0
RING1 -3707.0
CCNE1 -3688.0
ZNF703 -3683.0
RARG -3682.0
SUPT5H -3672.0
ZNF382 -3661.0
MECP2 -3660.0
SMAD4 -3639.0
PAX5 -3632.0
CDK2 -3614.0
PSMB1 -3610.0
ATRIP -3603.0
ZNF19 -3587.0
RAD51 -3583.0
ZNF610 -3580.0
UBA52 -3490.0
ZNF324 -3489.0
ZNF250 -3486.0
ZNF521 -3453.0
ZNF670 -3401.0
DEK -3397.0
POLR2B -3384.0
ZNF546 -3301.0
TACO1 -3299.0
ZNF486 -3296.0
ZNF714 -3288.0
ZNF564 -3260.0
RAD50 -3254.0
ZNF324B -3252.0
ZNF689 -3229.0
ZNF595 -3227.0
SMARCE1 -3212.0
CDKN1B -3127.0
ESR1 -3021.0
SOCS4 -2988.0
AXIN1 -2986.0
UBE2E1 -2985.0
MED27 -2978.0
CBX2 -2958.0
ZNF557 -2919.0
EXO1 -2916.0
RPAP2 -2876.0
YES1 -2846.0
MED30 -2845.0
PSMA2 -2823.0
NELFA -2822.0
SLBP -2817.0
TNFRSF10A -2801.0
ZNF561 -2797.0
ZNF418 -2796.0
RPRD2 -2788.0
PSMA4 -2764.0
ZNF77 -2710.0
ANAPC4 -2692.0
STUB1 -2688.0
SMARCB1 -2683.0
CNOT10 -2678.0
NR4A1 -2672.0
EHMT2 -2671.0
RRAGB -2658.0
MED17 -2648.0
THOC2 -2624.0
CDK1 -2593.0
ZNF558 -2569.0
CNOT2 -2544.0
THOC6 -2527.0
MT-CO2 -2523.0
PSMD10 -2515.0
MED31 -2514.0
RRM2 -2442.0
WDR61 -2390.0
PHC3 -2377.0
UBE2I -2356.0
NUAK1 -2339.0
SIRT3 -2325.0
MED4 -2264.0
WDR5 -2237.0
ZNF791 -2198.0
ALYREF -2176.0
SRRM1 -2172.0
U2AF1L4 -2154.0
DAXX -2153.0
PF4 -2122.0
ZNF264 -2113.0
INTS9 -2090.0
ZNF585A -2053.0
THRA -2010.0
ZC3H11A -2004.0
ZNF169 -1961.0
NR4A3 -1943.0
ZNF160 -1941.0
BRD7 -1932.0
PRKAG2 -1916.0
ZNF436 -1909.0
SKP2 -1895.0
CLDN5 -1869.0
FIP1L1 -1860.0
ANAPC10 -1816.0
ZNF724 -1814.0
PABPN1 -1789.0
PPARGC1A -1762.0
CDC26 -1744.0
ZNF720 -1737.0
ING2 -1723.0
NR2C2 -1712.0
GTF2H5 -1698.0
ZNF717 -1691.0
ZNF684 -1667.0
ZNF624 -1616.0
BBC3 -1611.0
ZNF665 -1605.0
ZNF221 -1593.0
SRSF1 -1573.0
ZNF41 -1570.0
L3MBTL1 -1539.0
ZNF676 -1527.0
RBM14 -1512.0
RBM8A -1499.0
NR4A2 -1447.0
FBXW7 -1315.0
ZNF100 -1250.0
CALM1 -1245.0
GTF2A1 -1202.0
ZNF565 -1174.0
ZNF34 -1172.0
MYBL2 -1171.0
RPTOR -1137.0
ZNF547 -1122.0
ZNF667 -1090.0
PCGF6 -1085.0
RBBP5 -1075.0
ZNF426 -1066.0
MLST8 -1064.0
DDB2 -1024.0
NOC2L -998.0
ZNF99 -982.0
MED1 -971.0
DDX39B -960.0
IFNG -958.0
TMEM219 -957.0
NCBP1 -942.0
ZNF197 -922.0
MED15 -911.0
CSTF2T -904.0
TFAP2E -902.0
CHEK2 -865.0
SNAPC5 -861.0
CSTF2 -856.0
ZNF195 -841.0
PML -815.0
GTF2H4 -803.0
LEO1 -778.0
ZNF71 -753.0
ATXN3 -673.0
ZNF589 -659.0
ATF2 -657.0
ZNF713 -656.0
SARNP -641.0
CCNT2 -632.0
ZNF700 -598.0
CPSF1 -561.0
POLR2C -494.0
WDR33 -474.0
TRIM33 -473.0
FANCC -455.0
MT-CO1 -454.0
PSMB8 -438.0
ZNF615 -407.0
DPY30 -319.0
TAF1 -304.0
TJP1 -300.0
COX4I1 -286.0
RMI2 -282.0
ZNF770 -273.0
ELF1 -271.0
STK11 -238.0
BRD2 -209.0
RELA -204.0
ZNF627 -194.0
PCGF2 -177.0
SNAPC4 -160.0
MAX -145.0
RNF34 -115.0
PPARGC1B -31.0
INTS10 37.0
CDKN2A 48.0
SMAD7 52.0
PPP2R1B 89.0
TAF11 95.0
BGLAP 197.0
HDAC6 243.0
RNF2 248.0
CDC27 283.0
CHD4 290.0
H2BU1 298.0
TNRC6B 301.0
OCLN 304.0
TNRC6A 318.0
THOC7 348.0
SLU7 354.0
PIP4K2A 379.0
TOPBP1 397.0
ZNF350 404.0
OPRM1 433.0
U2AF2 483.0
ANAPC7 498.0
CBFB 503.0
ZNF155 509.0
KMT2E 515.0
ZNF655 517.0
PLK2 549.0
SNRPG 560.0
PIN1 577.0
ARID1B 588.0
PSMC4 605.0
ZNF222 626.0
MED13 630.0
PSMB4 642.0
HDAC1 650.0
ZNF699 661.0
ZNF442 703.0
ZNF764 733.0
CCNB1 735.0
ZNF747 780.0
TAF6 791.0
ZNF398 863.0
GAD2 875.0
E2F8 895.0
PSMC3 916.0
PSMD14 941.0
NR1H3 954.0
CITED4 960.0
ZNF562 990.0
CASP10 1005.0
NR3C1 1021.0
UBB 1026.0
ZNF189 1034.0
KLF4 1084.0
CHM 1115.0
PIP4K2C 1118.0
ZNF716 1137.0
GTF2B 1157.0
SYMPK 1165.0
MED7 1178.0
MED24 1185.0
MLH1 1189.0
CHTOP 1241.0
BRPF3 1249.0
FAS 1260.0
ZNF200 1270.0
ZNF124 1333.0
MDM4 1356.0
CDK5R1 1363.0
PRELID3A 1364.0
ZNF619 1399.0
TSC1 1403.0
ZNF443 1414.0
CNOT11 1459.0
TAF4 1471.0
NBN 1482.0
EIF4A3 1507.0
PRMT5 1582.0
ZNF641 1585.0
RPRD1A 1598.0
CTR9 1610.0
ZNF776 1623.0
NABP2 1635.0
ZNF750 1680.0
ZNF778 1729.0
ZKSCAN4 1738.0
RRAGC 1745.0
INTS7 1753.0
PSMB2 1760.0
MTOR 1777.0
ZKSCAN3 1789.0
NELFB 1812.0
PSME4 1818.0
SFN 1840.0
SMARCA2 1856.0
CCNA2 1863.0
MED23 1915.0
MYL9 1931.0
AURKB 1985.0
POLR2L 2016.0
CASP2 2017.0
ZNF660 2023.0
CCNH 2048.0
KAT2B 2054.0
SIN3B 2071.0
PSMD7 2084.0
RABGGTA 2092.0
BRPF1 2098.0
CDK13 2118.0
GTF2A2 2140.0
ZNF691 2191.0
POU2F2 2197.0
CAV1 2229.0
AGRP 2238.0
SREBF1 2292.0
ZNF658B 2299.0
CBX3 2333.0
ZNF669 2359.0
TCF12 2381.0
PRKAA1 2409.0
HDAC10 2431.0
GTF2E1 2433.0
APOE 2448.0
H2BC15 2474.0
CAMK2G 2528.0
GPS2 2541.0
AGO3 2552.0
ZNF587 2582.0
CBX8 2624.0
ZNF429 2657.0
HIVEP3 2666.0
ZNF79 2726.0
ZNF556 2729.0
CNOT8 2767.0
FOS 2787.0
RXRB 2848.0
NFKB1 2860.0
MTA2 2877.0
CASP1 2896.0
BANP 2945.0
CNOT4 3043.0
INTS12 3065.0
ZNF25 3085.0
RRM2B 3109.0
TAF2 3110.0
PSMA1 3111.0
JUN 3122.0
TAL1 3132.0
EHMT1 3155.0
COX5A 3171.0
TAF7 3179.0
PCF11 3209.0
SUPT4H1 3268.0
ZNF668 3291.0
GTF2H2 3309.0
ZNF320 3311.0
GCK 3322.0
SNW1 3347.0
SURF1 3355.0
GPX2 3367.0
HDAC5 3369.0
ERCC3 3424.0
RFFL 3429.0
INTS2 3437.0
SEM1 3454.0
CRADD 3517.0
UBE2C 3555.0
KAT5 3557.0
CCNE2 3568.0
ZKSCAN1 3585.0
ARID2 3609.0
CSTF3 3626.0
ZNF555 3636.0
MOBP 3646.0
ITGAL 3647.0
ZNF611 3658.0
ELOA 3736.0
PSMD13 3766.0
TCF7L1 3775.0
ZNF394 3785.0
PRDX1 3802.0
POMC 3862.0
ANAPC11 3904.0
ZNF347 3913.0
NPPA 3921.0
SNAPC3 3923.0
RTF1 3926.0
RBX1 3957.0
FZR1 3967.0
COX7A2L 3979.0
RNGTT 4041.0
SUMO1 4061.0
INTS8 4109.0
GP1BA 4136.0
ZNF215 4137.0
DDIT4 4138.0
CDK7 4155.0
MED16 4162.0
POLR2G 4175.0
ZNF701 4187.0
ZNF839 4197.0
HUS1 4236.0
CNOT1 4249.0
BARD1 4253.0
POLR2F 4256.0
PSMF1 4259.0
PSMD3 4297.0
TSC2 4311.0
CDK8 4340.0
H2AZ1 4378.0
TPX2 4403.0
NDUFA4 4421.0
RHEB 4425.0
COX7B 4513.0
BIRC5 4541.0
PSMC2 4543.0
KAT6A 4584.0
MAPKAP1 4588.0
THBS1 4645.0
ZNF718 4650.0
BNIP3L 4710.0
YWHAB 4721.0
INTS6 4729.0
UBE2S 4773.0
AFF4 4808.0
PSMC1 4827.0
ELL2 4850.0
TBL1XR1 4852.0
ZNF471 4855.0
PPARA 4862.0
ZNF586 4863.0
ZNF20 4882.0
DHX38 4887.0
ZFP69B 4901.0
ZNF490 4930.0
PSMC6 4959.0
ZNF205 4960.0
ZNF385A 5003.0
SERPINE1 5005.0
COX5B 5048.0
SSU72 5062.0
GPRIN1 5069.0
PAF1 5073.0
CDC40 5078.0
EAF2 5079.0
POLR2E 5109.0
ZNF775 5111.0
PPP2R1A 5189.0
YWHAZ 5202.0
PSMA6 5209.0
E2F4 5213.0
CBX6 5259.0
CTSK 5320.0
PAPOLA 5344.0
LAMTOR3 5383.0
RPRD1B 5395.0
KCTD6 5411.0
SUPT6H 5421.0
HDAC3 5437.0
H2AC6 5440.0
BAX 5446.0
HDAC11 5471.0
RFC2 5478.0
SLC38A9 5485.0
TEAD2 5487.0
ELL3 5492.0
AKT2 5502.0
TGFB1 5504.0
ZNF460 5515.0
CDKN1A 5537.0
CLP1 5591.0
POLR2J 5598.0
MED14 5610.0
CDK9 5620.0
VEGFA 5648.0
PSMD8 5687.0
KCTD1 5799.0
CDC25C 5800.0
ZNF613 5823.0
ZNF354A 5856.0
SMARCC2 5869.0
CSNK2B 5876.0
COX6A1 5884.0
CPSF7 5894.0
WWTR1 5902.0
CDK12 5907.0
PBRM1 5917.0
NR1I3 5969.0
GATAD2B 5985.0
TAF8 5995.0
LAMTOR4 6002.0
MDM2 6043.0
AGO2 6087.0
H2BC11 6121.0
ABL1 6127.0
KRAS 6132.0
ZNF143 6133.0
UBC 6135.0
ZNF697 6137.0
ZNF702P 6149.0
H2BC17 6188.0
CDC73 6229.0
HDAC8 6235.0
GTF2F2 6257.0
USP7 6259.0
SMAD2 6291.0
USP9X 6344.0
U2AF1 6360.0
RBBP8 6377.0
KMT2C 6410.0
INTS1 6441.0
LSM10 6472.0
DDIT3 6480.0
SMURF1 6481.0
AKT1 6498.0
ZFHX3 6518.0
PTPN11 6524.0
MED26 6537.0
TIGAR 6589.0
RAD9B 6597.0
RYBP 6609.0
ERCC2 6621.0
AR 6643.0
NFYA 6667.0
AURKA 6693.0
NELFE 6710.0
ZNF774 6717.0
GTF2F1 6738.0
ITCH 6755.0
H2BC5 6759.0
PPP2CA 6806.0
E2F1 6818.0
PSMD12 6820.0
SKIL 6851.0
TP53INP1 6853.0
PLK3 6889.0
GATAD2A 6890.0
ZKSCAN7 6896.0
TNFRSF10D 6912.0
ELOC 6974.0
GTF2E2 6979.0
CCNA1 7002.0
RNF111 7005.0
BRCA1 7032.0
G6PC 7036.0
SRSF4 7085.0
PRELID1 7109.0
GPI 7117.0
GSK3B 7147.0
PRKAB1 7148.0
CPSF2 7191.0
EAF1 7231.0
CNOT6 7242.0
JUNB 7257.0
SOD2 7284.0
PSMD6 7307.0
CPSF3 7310.0
CSNK2A2 7341.0
ITGA2B 7387.0
HDAC7 7388.0
PSMB6 7399.0
NRBP1 7428.0
ELOB 7435.0
CBX4 7438.0
PPP2CB 7451.0
ELF2 7487.0
ABCA6 7495.0
PLAGL1 7496.0
HES1 7535.0
BID 7544.0
PPM1D 7552.0
SETD1B 7555.0
SNAPC2 7561.0
PSMD5 7646.0
KCTD15 7676.0
SMARCD3 7698.0
MED12 7718.0
TBL1X 7764.0
PSMD11 7775.0
PRKAG1 7805.0
PSMA7 7840.0
POU2F1 7849.0
POLR2A 7852.0
ZKSCAN5 7864.0
SMARCA4 7879.0
KMT2B 7908.0
IRAK1 7970.0
PSMB3 8005.0
LAMTOR2 8006.0
COX6B1 8031.0
CCNK 8038.0
ZNF552 8044.0
COX8A 8092.0
MED25 8136.0
PSMD2 8139.0
CREBBP 8143.0
NCOR1 8153.0
PSMD1 8184.0
ELL 8187.0
ZNF333 8189.0
ZNF267 8220.0
JAG1 8240.0
RRAGD 8243.0
ZNF18 8255.0
PSMB5 8265.0
ANAPC15 8323.0
SMARCD2 8363.0
NOTCH2 8400.0
PSMB7 8460.0
CITED2 8503.0
HIPK1 8544.0
CNOT3 8550.0
PRKCB 8577.0
UBE2D3 8641.0
MED8 8643.0
ZNF468 8676.0
TFDP1 8682.0
PDPK1 8710.0
SRSF9 8713.0
PSME3 8716.0
TAF13 8718.0
IWS1 8736.0
ZNF282 8738.0
MED20 8757.0
PSMD9 8766.0
AGO1 8810.0
APAF1 8822.0
LBR 8834.0
TAF12 8850.0
ASH2L 8855.0
KMT2D 8863.0
LAMTOR5 8889.0
H2AC20 8893.0
ZNF28 8904.0
PPM1A 8912.0
H2BC4 8925.0
H3C15 8929.5
CDKN2B 8931.0
TNFRSF10B 8944.0
ZNF230 8954.0
YWHAE 8971.0
H3-3A 8985.0
NR6A1 9008.0
RMI1 9032.0
RRAGA 9038.0
CSNK2A1 9040.0
NRBF2 9084.0
NEDD4L 9088.0
TP53BP2 9121.0
TNFRSF10C 9127.0
BCL2L11 9144.0
LGALS3 9180.0
ESRRA 9192.0
FOXO4 9205.0
ZNF445 9223.0
SATB2 9256.0
LAMTOR1 9265.0
PRDX5 9267.0
TXN 9268.0
H2BC12 9280.0
UBE2D1 9286.0
CTDP1 9289.0
CCNG2 9366.0
KDM5B 9406.0
TAF10 9419.0
NOTCH1 9499.0
NR1H2 9521.0
GATA1 9542.0
PTEN 9545.0
ARID1A 9567.0
CASC3 9610.0
CSF1R 9627.0
ZNF213 9638.0
CTNNB1 9670.0
HTT 9679.0
TOP3A 9684.0
H2BC21 9690.0
SP1 9699.0
MAPK3 9750.0
SESN2 9768.0
LMO2 9776.0
STEAP3 9786.0
EP300 9789.0
FOXO3 9800.0
INTS3 9830.0
RB1 9839.0
ITGA5 9848.0
TXNRD1 9890.0
NDRG1 10027.0
MAML1 10046.0
YWHAH 10050.0
HIPK2 10064.0
RXRA 10073.0
DLX6 10075.0
ARID3A 10084.0
PSMD4 10088.0
CAT 10103.0
RBPJ 10176.0
POLDIP3 10182.0
ZNF746 10212.0
CTSL 10288.0
NOTCH4 10293.0
CARM1 10313.0
THOC5 10316.0
MLLT1 10332.0
TWIST2 10353.0
YWHAG 10453.0
KMT5A 10459.0
NFYC 10461.0
CCND3 10476.0
RUNX1 10531.0
PINK1 10533.0
AGO4 10537.0
NABP1 10575.0
ZNF710 10617.0
PTPN1 10623.0
CDK5 10628.0
MAML3 10651.0
SLC2A3 10714.0
RETN 10732.0
TCF7L2 10773.0
RARA 10808.0
SMAD6 10809.0
SOCS3 10826.0
HDAC4 10884.0
G6PD 10948.0
MAP2K6 10958.0
FKBP5 10974.0
TGFA 10983.0
GSR 11051.0
GADD45A 11089.0
MAPK14 11115.0
CEBPB 11136.0
PHC2 11145.0
MAPK1 11193.0
RNU1-1 11197.5
NCOR2 11217.0
SPI1 11223.0
NLRC4 11239.0
NFE2 11293.0
BCL6 11324.0
PRKACA 11363.0
VDR 11370.0
CR1 11401.0
SMAD1 11403.0
NOTCH3 11420.0
TP53I3 11439.0
H2AJ 11447.0
PPARG 11451.0


Signaling by Interleukins

Signaling by Interleukins
1100
set Signaling by Interleukins
setSize 385
pANOVA 7.78e-10
s.dist 0.183
p.adjustANOVA 2.16e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
CSF2RA 11457
IL1R2 11419
PRKACA 11363
MYD88 11331
BCL6 11324
MAP3K8 11291
STXBP2 11285
RHOU 11282
TIMP1 11275
ITGAM 11269
MAPKAPK3 11249
ITGAX 11231
FPR1 11221
S100A12 11206
HCK 11202
MAPK1 11193
PTK2B 11185
ALOX5 11178
MMP2 11162
IL10 11149

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CSF2RA 11457.0
IL1R2 11419.0
PRKACA 11363.0
MYD88 11331.0
BCL6 11324.0
MAP3K8 11291.0
STXBP2 11285.0
RHOU 11282.0
TIMP1 11275.0
ITGAM 11269.0
MAPKAPK3 11249.0
ITGAX 11231.0
FPR1 11221.0
S100A12 11206.0
HCK 11202.0
MAPK1 11193.0
PTK2B 11185.0
ALOX5 11178.0
MMP2 11162.0
IL10 11149.0
IL17RA 11148.0
IL10RB 11122.0
MAPK14 11115.0
VAMP7 11110.0
RPS6KA1 11103.0
NKIRAS2 11077.0
PTPN9 11075.0
HMOX1 11030.0
VIM 10996.0
TNFRSF1A 10988.0
IL27 10978.0
MAP2K6 10958.0
CD36 10947.0
MMP9 10920.0
LMNB1 10917.0
PTPN18 10915.0
IRAK3 10909.0
IL1RN 10874.0
ITGB2 10861.0
TYK2 10828.0
SOCS3 10826.0
LYN 10810.0
IL1R1 10792.0
INPPL1 10780.0
GRB2 10733.0
SERPINB2 10710.0
ANXA2 10704.0
ARF1 10610.0
CEBPD 10543.0
GAB2 10528.0
CSF3R 10480.0
PTPN6 10446.0
MAP3K3 10435.0
PITPNA 10422.0
HGF 10417.0
HAVCR2 10416.0
TALDO1 10395.0
CRK 10387.0
MAP2K3 10377.0
IL4R 10372.0
LCP1 10315.0
SYK 10256.0
VAV1 10226.0
PTAFR 10188.0
STX3 10186.0
MAP2K1 10148.0
P4HB 10093.0
PSMD4 10088.0
TNFRSF1B 10079.0
MAPK7 10035.0
NOD2 9983.0
LGALS9 9955.0
MSN 9917.0
CBL 9903.0
JAK3 9899.0
MEF2A 9891.0
STAT6 9852.0
FOXO3 9800.0
CFL1 9794.0
TEC 9787.0
MAOA 9761.0
MAPK3 9750.0
SOS2 9744.0
STAT3 9739.0
TOLLIP 9682.0
CSF1R 9627.0
CCR2 9605.0
SHC1 9541.0
CAPZA1 9530.0
CCR1 9507.0
EBI3 9478.0
IKBKG 9441.0
IRS2 9427.0
CSF2RB 9423.0
GSTO1 9188.0
PTPN2 9173.0
CNN2 9140.0
PIK3CB 9126.0
PELI3 9118.0
PAK2 9042.0
INPP5D 9020.0
HIF1A 9002.0
PIK3CD 8956.0
IL1RAP 8946.0
H3C15 8929.5
MAPKAPK2 8852.0
MAPK10 8849.0
PSMD9 8766.0
STAT5B 8742.0
CHUK 8723.0
PSME3 8716.0
DUSP3 8510.0
OSM 8499.0
PSMB7 8460.0
IL19 8416.0
CDC42 8342.0
PSMB5 8265.0
CA1 8217.0
PSMD1 8184.0
PSMD2 8139.0
PSMB3 8005.0
IRAK1 7970.0
SMARCA4 7879.0
POU2F1 7849.0
PSMA7 7840.0
STAT5A 7833.0
TNIP2 7810.0
PSMD11 7775.0
MAP2K4 7754.0
PTPN12 7724.0
IL18R1 7674.0
PSMD5 7646.0
IL6R 7534.0
PPP2CB 7451.0
PIM1 7419.0
PSMB6 7399.0
PSMD6 7307.0
SOD2 7284.0
JUNB 7257.0
IL18RAP 7209.0
VRK3 7206.0
PTPN23 7161.0
CXCL1 7072.0
STX4 7026.0
RAP1B 6962.0
NFKBIB 6845.0
PSMD12 6820.0
PPP2CA 6806.0
CTF1 6678.0
TAB3 6655.0
PPP2R5D 6601.0
PTPN11 6524.0
PIK3R2 6511.0
AKT1 6498.0
APP 6245.0
MCL1 6210.0
PELI2 6164.0
UBC 6135.0
IL27RA 5756.0
PSMD8 5687.0
OPRD1 5678.0
VEGFA 5648.0
FBXW11 5621.0
IL18 5580.0
CDKN1A 5537.0
TGFB1 5504.0
NFKBIA 5457.0
CRKL 5250.0
ANXA1 5228.0
PSMA6 5209.0
YWHAZ 5202.0
PPP2R1A 5189.0
RAPGEF1 5102.0
BCL2L1 4964.0
PSMC6 4959.0
AGER 4895.0
TBK1 4856.0
PSMC1 4827.0
PELI1 4802.0
SOCS1 4688.0
TRAF6 4673.0
PSMC2 4543.0
BIRC5 4541.0
MUC1 4458.0
JAK2 4428.0
CASP3 4426.0
RPS6KA2 4384.0
PSMD3 4297.0
PSMF1 4259.0
BATF 4052.0
MAP3K7 4043.0
IL17C 3994.0
RBX1 3957.0
POMC 3862.0
BOLA2 3823.0
IL33 3789.0
PSMD13 3766.0
MMP1 3753.0
CXCL2 3656.0
STX1A 3540.0
SEM1 3454.0
NANOG 3382.0
CANX 3332.0
JUN 3122.0
PSMA1 3111.0
FSCN1 3098.0
TXLNA 3083.0
HNRNPA2B1 3074.0
CASP1 2896.0
NFKB1 2860.0
FOS 2787.0
COL1A2 2707.0
PIK3R3 2676.0
ATF1 2556.0
IL1RL1 2334.0
NDN 2322.0
LCN2 2300.0
PIK3CA 2133.0
OSMR 2089.0
PSMD7 2084.0
TAB2 1975.0
PSME4 1818.0
PSMB2 1760.0
IKBKB 1759.0
TAB1 1754.0
MAP2K7 1550.0
IL13RA1 1505.0
F13A1 1493.0
FCER2 1492.0
HNRNPF 1319.0
ICAM1 1122.0
UBB 1026.0
PSMD14 941.0
PSMC3 916.0
LAMA5 751.0
RPS6KA3 649.0
PSMB4 642.0
PSMC4 605.0
PTPN14 506.0
PTGS2 444.0
OPRM1 433.0
SOCS5 292.0
PPP2R1B 89.0
CSF1 -182.0
IL6ST -192.0
RELA -204.0
PSMB8 -438.0
CISH -483.0
CLCF1 -518.0
PTPN7 -645.0
ATF2 -657.0
IL17RB -754.0
IL3RA -895.0
IL15RA -946.0
IFNG -958.0
IGHG1 -1043.0
IL10RA -1108.0
CCR5 -1251.0
UBE2V1 -1252.0
TNF -1341.0
S100B -1351.0
CNTF -1403.0
AIP -1433.0
CD86 -1606.0
PTPN20 -1692.0
HSP90B1 -1788.0
FN1 -1829.0
SQSTM1 -2046.0
UBE2N -2071.0
IL18BP -2072.0
IL16 -2114.0
DUSP4 -2116.0
IL4 -2190.0
CRLF1 -2210.0
IGHG4 -2238.0
RIPK2 -2451.0
DUSP7 -2452.0
PSMD10 -2515.0
PSMA4 -2764.0
IRAK2 -2799.0
PSMA2 -2823.0
YES1 -2846.0
SOS1 -2983.0
DUSP6 -3055.0
ITGB1 -3073.0
CCL4 -3160.0
SOCS2 -3165.0
IL15 -3244.0
IL1B -3269.0
CXCL8 -3280.0
UBA52 -3490.0
STAT2 -3493.0
NFKB2 -3527.0
PSMB1 -3610.0
NOD1 -3652.0
CCND1 -3813.0
CREB1 -3977.0
HSP90AA1 -4016.0
IL31RA -4022.0
PSMB10 -4050.0
S1PR1 -4161.0
BTRC -4212.0
TCP1 -4240.0
IL17RC -4347.0
PSMC5 -4553.0
CCL5 -4627.0
MAPK11 -4641.0
IL12RB1 -5165.0
FYN -5211.0
MAPK9 -5454.0
IFNLR1 -5734.0
BRWD1 -5820.0
ELK1 -5884.0
IL7 -5901.0
MEF2C -6025.0
IRS1 -6033.0
PTPN13 -6043.0
RAG1 -6228.0
FGF2 -6231.0
NKIRAS1 -6234.0
JAK1 -6261.0
BLNK -6294.0
SKP1 -6297.0
RALA -6392.0
PSMA3 -6433.0
PPIA -6498.0
MTAP -6590.0
IGHE -6665.0
HMGB1 -6699.0
SIGIRR -6838.0
CD4 -6881.0
IL20RB -6905.0
BCL2 -6977.0
ZEB1 -7028.0
MIF -7102.0
FASLG -7230.0
SNRPA1 -7256.0
PSME2 -7327.0
SOD1 -7420.0
IL21R -7467.0
PSMA5 -7476.0
IL2RA -7681.0
IL12A -7688.0
IL2RG -7711.0
PSME1 -7778.0
SMAD3 -7868.0
IL17RE -7873.0
IRF4 -8063.0
CD80 -8215.0
IL5RA -8245.0
CCL3 -8305.0
PTPN4 -8389.0
IL12RB2 -8465.0
PSMB9 -8503.0
VAMP2 -8673.0
STAT4 -8814.0
PIK3R1 -8831.0
MAPK8 -8929.0
IL32 -8976.0
HNRNPDL -9013.0
IL11RA -9023.0
HSPA8 -9129.0
TP53 -9170.0
RORA -9193.0
RPLP0 -9227.0
PRTN3 -9350.0
MYC -9357.0
RPS6KA5 -9386.0
CUL1 -9420.0
STAT1 -9448.0
ALOX15 -9484.0
CTSG -9503.0
IL24 -9522.0
LCK -9556.0
IL2RB -9646.0
RPS27A -9723.0
FOXO1 -9731.0
HSPA9 -9747.0
PDCD4 -9947.0
IL9R -9991.0
IL23A -9994.0
CXCL10 -10060.0
GATA3 -10071.0
IL7R -10153.0
RORC -10162.0


Mitochondrial translation elongation

Mitochondrial translation elongation
668
set Mitochondrial translation elongation
setSize 91
pANOVA 8.68e-10
s.dist -0.372
p.adjustANOVA 2.32e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
MRPS6 -9838
GFM1 -9467
MRPS33 -9440
MRPL50 -9302
MRPS25 -9279
MRPS27 -9147
MRPS9 -8917
MRPL48 -8859
MRPL24 -8692
MRPL46 -8479
MRPS30 -8262
MRPS18B -8125
MRPL17 -8047
MRPL32 -7992
MRPL39 -7936
MRPL1 -7594
MRPL38 -7496
MRPS2 -7237
MRPL42 -7224
MRPL9 -7188

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MRPS6 -9838
GFM1 -9467
MRPS33 -9440
MRPL50 -9302
MRPS25 -9279
MRPS27 -9147
MRPS9 -8917
MRPL48 -8859
MRPL24 -8692
MRPL46 -8479
MRPS30 -8262
MRPS18B -8125
MRPL17 -8047
MRPL32 -7992
MRPL39 -7936
MRPL1 -7594
MRPL38 -7496
MRPS2 -7237
MRPL42 -7224
MRPL9 -7188
DAP3 -7087
MRPL45 -6990
MRPS17 -6909
MRPL14 -6728
MRPS14 -6718
MRPS7 -6677
PTCD3 -6500
MRPS21 -6319
MRPS28 -6255
TSFM -6082
MRPL35 -5957
MRPL3 -5916
MRPS12 -5654
MRPL49 -5619
MRPL54 -5616
MRPL11 -5474
MRPS26 -5430
MT-RNR1 -5094
MRPL57 -5039
MRPL34 -4765
MRPL43 -4449
MRPL27 -4262
MRPS23 -4230
MRPL19 -4123
MRPL58 -3985
MRPS31 -3868
MRPL12 -3819
MRPL55 -3524
MRPL41 -3438
MRPS35 -3315
MRPL18 -3314
MRPL40 -2981
MRPL15 -2975
GADD45GIP1 -2813
MRPS10 -2725
MRPL21 -2473
MRPL2 -2449
MRPL30 -2421
MRPS22 -2388
MRPS34 -2208
MRPS18C -2145
MRPL47 -2119
MRPL4 -1924
MRPL16 -1832
MRPL20 -1647
ERAL1 -1389
MRPS15 -924
MRPS36 -492
MRPL22 -462
MT-RNR2 -408
MRPL13 -237
MRPL37 177
MRPS16 350
MRPS24 1048
MRPS18A 1407
MRPL36 1646
OXA1L 1825
MRPL44 1847
MRPS11 2087
MRPS5 2484
MRPL51 2595
MRPL33 2637
MT-TV 3363
TUFM 3457
CHCHD1 3643
MRPL52 4004
MRPL10 4156
MRPL23 4865
AURKAIP1 5758
MRPL53 6626
MRPL28 9785


Clathrin-mediated endocytosis

Clathrin-mediated endocytosis
189
set Clathrin-mediated endocytosis
setSize 127
pANOVA 8.71e-10
s.dist 0.315
p.adjustANOVA 2.32e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
AP2A1 11340
AMPH 11248
SNX18 11203
VAMP7 11110
TGFA 10983
ARPC1A 10981
ITSN1 10737
GRB2 10733
EPN1 10697
ARRB2 10688
DAB2 10645
LDLR 10634
SYNJ1 10567
HIP1 10519
AGFG1 10514
IGF2R 10494
DNM2 10373
TGOLN2 10307
CLTC 10304
PACSIN2 10295

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AP2A1 11340
AMPH 11248
SNX18 11203
VAMP7 11110
TGFA 10983
ARPC1A 10981
ITSN1 10737
GRB2 10733
EPN1 10697
ARRB2 10688
DAB2 10645
LDLR 10634
SYNJ1 10567
HIP1 10519
AGFG1 10514
IGF2R 10494
DNM2 10373
TGOLN2 10307
CLTC 10304
PACSIN2 10295
PICALM 10243
AP2A2 10223
ARPC5 10102
REPS2 10081
CBL 9903
RAB5C 9864
GRK3 9662
SCARB2 9643
SH3GL1 9632
ARPC4 9592
GRK2 9386
OCRL 9323
HGS 9317
VAMP3 9311
GAK 9209
CLTCL1 9201
TOR1B 9184
ARPC2 9016
ACTR2 8895
ACTR3 8873
GAPVD1 8844
TOR1A 8807
AP2M1 8799
ARPC3 8726
COPS7A 8712
EPS15L1 8461
RAB5B 8258
SYT2 8154
AP2S1 8045
CLTB 7968
KIAA0319 7910
PIP5K1C 7742
NEDD8 7558
FNBP1L 7449
STAM2 7431
FCHO2 7311
CLTA 7164
RAB5A 7154
SYT11 6842
ITSN2 6557
UBC 6135
EPS15 6059
DNM1 5998
NECAP1 5923
SH3KBP1 5885
UBQLN2 5531
SYT1 5438
UBQLN1 5365
EGF 5267
FNBP1 4869
TFRC 4842
LRP2 4295
ARRB1 3956
COPS5 3579
DNM3 3523
FZD4 3498
AVPR2 3452
WASL 3297
CFTR 3091
ARF6 3007
ARFGAP1 2978
AP2B1 2910
EPN2 2846
DNAJC6 2611
AREG 2386
HBEGF 2064
SNX9 1918
COPS3 1310
TF 1246
UBB 1026
STON1 956
COPS2 934
STAM 907
VAMP4 607
CTTN 514
VAMP8 -139
REPS1 -150
EREG -249
STON2 -635
FCHO1 -1148
EPGN -1241
COPS6 -1242
PIK3C2A -1501
GPS1 -2376
COPS4 -2731
ADRB2 -3128
AAK1 -3358
UBA52 -3490
COPS7B -3712
NECAP2 -3755
M6PR -4860
DVL2 -5637
TRIP10 -6094
SLC2A8 -6202
CD4 -6881
CD3G -8111
CD3D -8297
HIP1R -8608
VAMP2 -8673
COPS8 -8830
HSPA8 -9129
BIN1 -9243
SYNJ2 -9322
PACSIN1 -9553
RPS27A -9723
LDLRAP1 -10002
IL7R -10153


Post-translational protein modification

Post-translational protein modification
839
set Post-translational protein modification
setSize 1190
pANOVA 1.08e-09
s.dist 0.105
p.adjustANOVA 2.83e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
FAM20A 11467
PPARG 11451
F5 11434
NPL 11416
SERPINA1 11407
SMAD1 11403
VDR 11370
QSOX1 11369
LAMC1 11344
GCNT1 11290
FAM20C 11284
TIMP1 11275
TPST1 11241
EPAS1 11229
FBXO9 11219
FSTL3 11218
NCOR2 11217
ADAMTSL4 11209
LGALS1 11177
GALNT14 11155

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FAM20A 11467
PPARG 11451
F5 11434
NPL 11416
SERPINA1 11407
SMAD1 11403
VDR 11370
QSOX1 11369
LAMC1 11344
GCNT1 11290
FAM20C 11284
TIMP1 11275
TPST1 11241
EPAS1 11229
FBXO9 11219
FSTL3 11218
NCOR2 11217
ADAMTSL4 11209
LGALS1 11177
GALNT14 11155
KLHL2 11154
B4GALT5 11150
PHC2 11145
COPG1 11142
VCAN 11140
ASGR2 11123
RHOT1 11096
TRIM25 11088
NEU1 11082
ST6GALNAC3 11069
ST3GAL2 11056
H2BC18 11047
ADAMTS3 11036
PCSK9 11027
VNN1 11000
RNF135 10992
TGFA 10983
FBXL19 10975
TUBB2A 10959
RAB10 10956
OS9 10951
RNF146 10941
APLP2 10928
CD55 10914
FURIN 10905
GALNT2 10885
HDAC4 10884
WSB1 10845
CTSA 10842
MAN1A1 10830
SOCS3 10826
MRTFA 10825
CKAP4 10819
RARA 10808
SEC24D 10803
USP3 10802
ADAMTS2 10727
TADA3 10717
IGFBP7 10708
USP4 10702
ARRB2 10688
DCTN4 10682
RAB3D 10677
METTL22 10676
RAB31 10661
NUCB1 10654
BST1 10647
ALPL 10638
RAB32 10626
RAB13 10611
ARF1 10610
ACTB 10606
LRRC41 10583
UIMC1 10578
COPA 10521
PLAUR 10490
TNIP1 10483
WDTC1 10479
EDEM2 10457
DCTN2 10412
SNX3 10408
B3GNT8 10405
MBD6 10396
FBXW2 10370
UBE2R2 10366
PREB 10364
ASB1 10342
TRIM27 10324
PNPLA2 10314
ACTR1A 10310
TGOLN2 10307
RNF40 10299
MAN2A2 10274
TPST2 10270
RAB39A 10255
ST3GAL4 10218
GLB1 10217
NUP214 10131
RAD23B 10127
SUMF1 10121
RAB7A 10115
P4HB 10093
PSMD4 10088
FBXL5 10086
RXRA 10073
HIPK2 10064
RAB1B 10055
ARSB 10041
ADAM10 9992
COG7 9987
NOD2 9983
RAB1A 9971
RAB6A 9958
UBE2F 9951
PIGS 9950
CTSZ 9943
RNF123 9932
JOSD2 9929
GAS6 9901
NRN1 9880
NTNG2 9877
LAMB1 9873
NSF 9870
RAB5C 9864
CDC34 9836
DNAJC3 9831
UBA1 9819
EP300 9789
DCAF6 9783
USP49 9766
H2BC21 9690
APOA2 9687
VNN2 9671
RAB24 9634
GORASP1 9633
RAB27A 9628
WAC 9624
TTLL4 9622
KDELR1 9613
RAB2A 9581
NUP58 9577
CAPZB 9575
FBXL18 9559
DCTN1 9558
PTEN 9545
AGTPBP1 9540
CHST8 9536
MPDU1 9532
CAPZA1 9530
NR1H2 9521
WSB2 9492
LMAN2 9480
ARF3 9465
SEC16A 9460
TMEM132A 9453
RAB40C 9448
IKBKG 9441
TAF10 9419
RAB34 9418
SEC24A 9414
GOLGA2 9412
ADAMTS14 9403
RHOA 9401
UBE2A 9364
TUBB3 9356
ARF4 9348
HGS 9317
UBE2D1 9286
SP100 9281
H2BC12 9280
UGGT2 9278
CTSC 9276
SATB2 9256
MELTF 9243
FOXO4 9205
PPP6R1 9179
NANS 9176
RAB42 9170
TUBA1A 9164
B3GNTL1 9156
TRAPPC1 9087
UBE2H 9080
ST8SIA4 9069
CALU 9049
RRAGA 9038
PIGB 9030
HIF1A 9002
SEC24C 8993
FBXL13 8980
NLRP3 8955
PIAS4 8952
H2BC4 8925
SEC16B 8899
COPB2 8898
H2AC20 8893
CFP 8875
RPN2 8874
GALNT4 8866
STS 8843
GALNT3 8797
PSMD9 8766
PEX14 8756
MITF 8744
PSME3 8716
COPS7A 8712
COPG2 8709
CMAS 8693
UBE2D3 8641
ALB 8630
TADA2B 8627
C1GALT1C1 8580
KDM1B 8552
FKBP8 8551
STX5 8547
CCDC22 8511
DHDDS 8480
CSNK1D 8475
DDOST 8464
PSMB7 8460
ARSA 8456
RAB4B 8449
TUBB4B 8440
RENBP 8438
USP19 8433
B3GNT5 8427
COG4 8402
RAB36 8383
GCNT7 8334
SHISA5 8330
GGCX 8321
HCFC1 8315
ARF5 8313
TTLL7 8278
DYNC1LI1 8276
ETFB 8274
PSMB5 8265
IKBKE 8263
RAB5B 8258
COPE 8230
XRCC4 8226
CAPZA2 8225
RNF185 8206
MIA2 8200
PSMD1 8184
TUBA1B 8174
CREBBP 8143
PSMD2 8139
MAVS 8131
FBXO11 8126
TFG 8124
HIF3A 8123
CPM 8111
SOCS6 8074
ANKRD9 8048
TMED9 8028
F8 8026
ST6GALNAC2 8010
PSMB3 8005
YOD1 8002
KEAP1 7998
COPB1 7997
PMM1 7991
H2AC11 7980
COL7A1 7971
GPAA1 7960
ASGR1 7956
MBD5 7940
TFPT 7914
NCOA2 7898
MGAT4B 7889
SEL1L 7883
PSMA7 7840
TNIP2 7810
VCP 7804
ARSD 7786
FBXL20 7776
PSMD11 7775
B4GALT1 7763
UBA3 7741
RAB8B 7739
CALR 7713
SPTB 7702
TUBA1C 7694
SUMO3 7693
GBF1 7683
KBTBD7 7650
PSMD5 7646
DYNC1LI2 7644
GALNT5 7641
YKT6 7621
LSAMP 7590
NEDD8 7558
VNN3 7545
DCTN6 7540
GMPPA 7523
RAB35 7522
NAPG 7516
SEC13 7506
MGAT1 7476
SERPIND1 7470
RNF7 7458
CBX4 7438
ELOB 7435
STAM2 7431
ARFGAP3 7424
UBE2M 7401
PSMB6 7399
BCL10 7391
HDAC7 7388
FBXO40 7369
SEC24B 7352
PIGF 7343
UBE2L3 7330
SEMA5B 7319
B3GNT2 7317
FPGT 7315
PSMD6 7307
EDEM3 7305
PEX5 7290
UBE2J2 7267
MBD1 7200
USP8 7180
COMMD9 7156
RAB5A 7154
RPN1 7151
SIAH2 7137
SEC23A 7129
UGGT1 7118
RAB18 7038
BRCA1 7032
RTN4RL2 7013
ST8SIA5 7003
CCNA1 7002
LYPD2 6994
PIAS1 6991
ELOC 6974
ARCN1 6965
SRD5A3 6925
TUBB6 6922
INO80C 6909
ZBTB16 6902
SAR1B 6893
ANO8 6886
NCOA1 6885
TOP1 6869
RAB43 6846
PRKCSH 6831
STAMBP 6828
PSMD12 6820
ASB4 6804
ZBED1 6763
H2BC5 6759
GALNT10 6754
OTOA 6743
DPH3 6721
DYNC1I2 6705
AURKA 6693
NAPA 6660
AR 6643
DCUN1D3 6638
DCTN3 6625
RAB11A 6617
TRAPPC9 6548
USP22 6538
SP3 6534
RNF20 6531
GALNT1 6495
MBTPS1 6492
BAP1 6478
FUCA1 6469
DCAF5 6457
ADRM1 6448
B4GALNT2 6427
MUC5B 6394
KDELR2 6387
B4GALT4 6368
USP9X 6344
PIGT 6341
GALNT7 6339
MUC16 6329
SCFD1 6297
AMFR 6296
SMAD2 6291
RAB3A 6284
SEC22B 6272
USP7 6259
COMMD7 6253
APP 6245
PIGZ 6239
CDC73 6229
CUL3 6200
DCAF10 6199
RAB21 6196
H2BC17 6188
TMEM115 6183
FEM1C 6159
UBC 6135
H2BC11 6121
CD109 6110
NICN1 6096
PIGN 6079
RAB7B 6060
UBE2W 6055
MDM2 6043
FUCA2 6028
GOSR2 5986
KIN 5980
CUL7 5972
IDE 5927
SENP2 5903
ASB8 5895
USP10 5893
ACTR10 5886
RAB19 5879
NUP98 5874
NUS1 5849
THSD4 5846
TECTA 5829
BECN1 5824
TGFBR2 5802
ALG12 5750
FBXL4 5725
SERPINA10 5708
SYVN1 5702
PSMD8 5687
ANK1 5655
PEX2 5624
FBXW11 5621
DDA1 5617
HNRNPK 5529
RAB20 5526
RAB8A 5522
TGFB1 5504
RAB14 5469
TTLL3 5465
NFKBIA 5457
PIGV 5451
FBXW5 5443
H2AC6 5440
PDIA6 5425
KCTD6 5411
ITIH2 5377
TTLL13P 5358
TMED2 5345
RNF152 5284
PSMA6 5209
JOSD1 5194
UBE2K 5166
FEM1A 5135
MCFD2 5134
GCNT3 5129
PTP4A2 5128
GALNT15 5095
PAF1 5073
FBXO6 5033
APC 5030
RAB33B 5028
SLC35C1 5026
ASB6 5017
RAE1 5007
COMMD5 5006
TTLL12 4997
UBA6 4974
TGFBR1 4966
PSMC6 4959
ZRANB1 4897
POMK 4885
PPARA 4862
RNF168 4839
GALNT6 4837
PSMC1 4827
UBE2S 4773
NFRKB 4748
TDG 4742
SPTBN5 4732
TRAF6 4673
CDC20 4670
TMEM129 4667
THBS1 4645
ASXL2 4631
CP 4630
ALG14 4622
OTUD5 4604
PIAS3 4559
SMC1A 4551
PSMC2 4543
BIRC5 4541
RNF181 4536
METTL21A 4459
MUC1 4458
TRAPPC3 4443
FBXO30 4415
SENP8 4405
SEC31A 4346
MAGT1 4339
ARFGAP2 4331
FBXO7 4309
SPSB2 4305
SLC17A5 4301
PSMD3 4297
HNRNPC 4266
KLHL21 4260
PSMF1 4259
BRCC3 4257
BARD1 4253
CD59 4252
B4GALT6 4216
PROS1 4191
CNIH2 4186
PDIA3 4101
UBE2B 4086
TSTA3 4081
SPTA1 4063
SUMO1 4061
MGAT2 4055
MAP3K7 4043
RAD23A 4034
ETFBKMT 4005
TMED7 3978
RAB11B 3969
ADAMTSL3 3958
RBX1 3957
ARRB1 3956
UBE2G1 3951
TBC1D20 3947
RTF1 3926
INCENP 3884
USP15 3819
IL33 3789
PSMD13 3766
PPP6R3 3723
DNMT3B 3720
NRIP1 3702
ENAM 3683
DCAF11 3653
DPM2 3619
COPS5 3579
UBE2C 3555
KLHL9 3525
TNKS2 3514
FCSK 3513
ST6GALNAC4 3458
SEM1 3454
TMED3 3420
TPGS2 3396
PROC 3380
LYPD5 3377
CANX 3332
TTLL5 3314
TRAPPC5 3257
GALNT16 3249
GANAB 3230
ST3GAL6 3223
RIPK1 3206
NAPB 3180
TPGS1 3133
PSMA1 3111
CFTR 3091
SUDS3 3040
MVD 3037
C4A 3032
ARFGAP1 2978
CTBP1 2903
STT3A 2891
POMGNT2 2881
OTUB1 2880
DYNC1I1 2879
DDB1 2849
RAD52 2805
SPSB1 2791
UBXN7 2777
SAFB 2708
BIRC2 2697
RAB23 2681
UBXN1 2648
NUP50 2638
GMPPB 2632
VHL 2627
CBX8 2624
CUL9 2601
FOXK2 2594
COMMD8 2593
TRAPPC10 2565
GAN 2551
FBXO41 2546
MUC6 2538
ERCC8 2532
KBTBD6 2491
FBN1 2489
H2BC15 2474
DCUN1D1 2459
APOE 2448
ASB7 2446
USO1 2424
AREG 2386
COMMD1 2378
MUL1 2370
COG5 2352
SDC2 2325
NSMCE2 2314
COMMD10 2305
TTL 2301
RAB3B 2284
TULP4 2261
STAG2 2247
GMDS 2239
VCPIP1 2234
ST6GAL2 2226
PRSS21 2177
FEM1B 2143
PPP6C 2138
RABGGTA 2092
PSMD7 2084
KAT2B 2054
SLC35A1 2052
ADAMTS6 2013
AURKB 1985
CLSPN 1968
DAD1 1941
MFGE8 1932
SENP1 1920
FSTL1 1916
CCNA2 1863
PARK7 1827
PSME4 1818
TOP2A 1801
PSMB2 1760
TAB1 1754
CCP110 1752
CST3 1747
DYNC1H1 1705
NSMCE1 1651
FBXL15 1627
CTR9 1610
LMAN2L 1586
USP48 1564
VCPKMT 1559
DYNLL1 1530
MANEA 1515
RAB41 1488
XPNPEP2 1463
FCGR3B 1391
MDM4 1356
PIGO 1348
TRAPPC6B 1327
COPS3 1310
TF 1246
USP34 1199
LTBP1 1164
INO80D 1160
CUL4B 1141
CHM 1115
TNC 1095
ACTR8 1087
COMMD4 1049
UBB 1026
NR3C1 1021
INO80 1015
VDAC2 985
NR1H3 954
PSMD14 941
COPS2 934
PSMC3 916
STAM 907
FBXO15 898
KDELR3 869
GPLD1 854
DOLK 844
MLEC 796
OBSL1 790
RAB27B 774
FOXK1 755
MARCHF6 740
SEC23IP 737
HDAC1 650
PSMB4 642
PEX10 637
RAB33A 620
PSMC4 605
ALG1 491
COPZ1 412
COG8 406
ZNF350 404
TRIM13 367
DPM3 335
AGBL5 329
FBXL12 328
CDC25A 317
CDCA8 310
H2BU1 298
DCTN5 297
SOCS5 292
BABAM1 270
DAG1 261
NUP153 254
RNF2 248
ARSG 247
BGLAP 197
ADAMTS13 147
ICMT 133
IGFBP4 122
SMAD7 52
DERL2 50
CDKN2A 48
TNKS 15
PIGG -29
CUL2 -38
WDR20 -41
LAMB2 -47
HLA-B -98
PEX13 -100
RNF103 -101
RAB15 -126
POM121 -142
SENP5 -164
USP25 -175
PCGF2 -177
CSF1 -182
RELA -204
SPTBN2 -220
FBXO27 -222
RFT1 -227
ASB14 -229
FBXO17 -234
HIC1 -260
PIGQ -289
FBXL3 -315
ALG10 -316
NEGR1 -335
B3GALNT2 -409
PSMB8 -438
CISH -483
DDX17 -506
NEU3 -511
DCUN1D5 -528
OTULIN -565
ASB13 -571
ADAMTS4 -589
MCRS1 -660
ATXN3 -673
MAN1B1 -683
FBXW9 -691
LEO1 -778
ALG6 -798
UBE2D2 -801
PML -815
NGLY1 -846
MYSM1 -876
NEURL2 -917
USP47 -1011
INO80B -1016
UBE2E3 -1020
DPAGT1 -1022
DDB2 -1024
RAB37 -1057
RBBP5 -1075
TRRAP -1100
DHPS -1104
RANBP2 -1141
PROZ -1150
VDAC1 -1213
VDAC3 -1232
COPS6 -1242
CALM1 -1245
NANP -1263
DCAF7 -1269
CUL4A -1277
SSPO -1281
GOLM1 -1299
SELENOS -1307
FBXW7 -1315
C1GALT1 -1362
POMT2 -1374
DPM1 -1376
CCDC8 -1407
CCNF -1413
USP13 -1429
FBXO22 -1440
USP12 -1445
NR4A2 -1447
USP18 -1497
TOPORS -1550
BET1L -1574
TUBB1 -1576
COMMD2 -1621
SUMO2 -1665
RAB4A -1669
TNIP3 -1673
CETN2 -1682
DOLPP1 -1706
POM121C -1710
RAB9A -1713
ING2 -1723
ALG2 -1755
PPARGC1A -1762
KBTBD8 -1765
ADAMTS16 -1770
GALNT11 -1773
HSP90B1 -1788
B4GALT2 -1790
FN1 -1829
RAB6B -1849
TRAPPC2L -1855
MUC12 -1866
SKP2 -1895
RNF139 -1918
MOGS -1931
EDEM1 -1934
USP30 -1938
FGF23 -1952
SPSB3 -1955
PIGX -1976
THRA -2010
B3GNT4 -2026
DNMT3A -2045
ASB3 -2060
UBE2N -2071
USP33 -2081
RAB12 -2139
DAXX -2153
COG3 -2175
UBE2V2 -2193
WDR5 -2237
KLHL42 -2261
NUP37 -2275
TNFAIP3 -2285
ASB16 -2287
KTN1 -2306
UBE2I -2356
GPS1 -2376
PHC3 -2377
WDR61 -2390
NUP62 -2410
RIPK2 -2451
RAB22A -2476
TRAPPC4 -2490
PSMD10 -2515
FBXO10 -2581
CDK1 -2593
KLHL11 -2610
PIGM -2611
NRN1L -2654
COMMD3 -2657
CNIH1 -2698
COPS4 -2731
BTBD1 -2747
PSMA4 -2764
PIGC -2820
PSMA2 -2823
PIGA -2826
CUL5 -2872
RAB29 -2900
ALG11 -2911
CBX2 -2958
UBE2E1 -2985
AXIN1 -2986
ESR1 -3021
ADAMTS1 -3036
FBXL8 -3037
OTUB2 -3068
DCUN1D2 -3077
GOSR1 -3080
GNE -3093
ADRB2 -3128
SEC22C -3143
SOCS2 -3165
AGBL2 -3170
RAD21 -3191
PIAS2 -3259
RCE1 -3302
RAB38 -3316
ALG13 -3317
AAAS -3332
APOL1 -3354
TTLL1 -3376
C3 -3394
AMDHD2 -3410
RAB44 -3423
NUP85 -3427
USP24 -3440
FBXW12 -3487
UBA52 -3490
GALNT8 -3492
NFKB2 -3527
HERC2 -3535
MGAT4C -3553
MUCL1 -3608
PSMB1 -3610
DCAF8 -3636
SMC6 -3637
SMAD4 -3639
NOD1 -3652
CHST10 -3667
MIA3 -3686
RNF5 -3693
RING1 -3707
COPS7B -3712
MSLN -3735
TPR -3744
OGT -3772
ATXN7 -3783
PTRH2 -3796
EIF5A -3834
USP21 -3859
CD52 -3861
PRSS23 -3916
NUP210 -3949
GFPT1 -3965
MDGA1 -3967
USP14 -3980
USP42 -3996
GOLGB1 -4004
MAN2A1 -4015
USP28 -4038
NUP42 -4045
THSD7A -4046
PSMB10 -4050
STAG1 -4051
PRKDC -4064
KLHL13 -4118
MAN1A2 -4146
RAB9B -4177
BTRC -4212
FBXW8 -4215
THRB -4237
SHPRH -4352
RWDD3 -4386
TTLL11 -4396
TMED10 -4413
CNIH3 -4435
MTA1 -4442
KLHL20 -4513
PSMC5 -4553
ALG3 -4562
ST8SIA6 -4572
DTL -4582
LY6E -4623
FUOM -4628
PIGH -4675
PGM3 -4706
ASB2 -4806
DOHH -4828
UCHL3 -4844
FBXL14 -4884
DYNLL2 -4904
CHML -4951
TOP2B -4985
RAB2B -4989
ASB9 -5007
USP5 -5041
PRMT3 -5042
RCN1 -5096
NAGK -5108
YY1 -5142
BLM -5151
ST3GAL5 -5223
ST3GAL3 -5250
FUT8 -5277
USP37 -5282
BTBD6 -5304
SUZ12 -5320
THSD1 -5327
ALG8 -5338
NUP133 -5346
MEN1 -5364
OTUD7A -5405
ST6GALNAC6 -5407
ALG5 -5433
USP44 -5436
PMM2 -5443
PIGP -5469
FBXO2 -5482
MGAT5 -5546
COG2 -5554
MUC4 -5589
NUDT14 -5651
ADAMTS10 -5655
ANKRD28 -5681
LRR1 -5690
DPH7 -5715
PEX12 -5722
H2BC9 -5728
GFPT2 -5748
OTUD3 -5750
OTUD7B -5751
B4GALT3 -5794
SMURF2 -5858
ST3GAL1 -5904
COPZ2 -5974
HLA-A -5985
PUM2 -6020
FN3K -6026
H2AW -6069
SMC3 -6091
ARSJ -6097
FBXL22 -6147
MGAT3 -6227
SPON2 -6247
EEF2 -6279
SKP1 -6297
ADAMTS5 -6323
BET1 -6342
SMC5 -6346
SBSPON -6428
PSMA3 -6433
INO80E -6456
NUP93 -6458
DERL1 -6490
TUBA3D -6511
B3GLCT -6513
CHD3 -6523
DPH6 -6542
FBXO44 -6558
DPH5 -6572
DDX5 -6600
CBX5 -6643
COG6 -6645
WFS1 -6669
USP16 -6670
ADAMTS17 -6697
CAMKMT -6707
XPC -6710
UHRF2 -6780
LARGE2 -6842
HDAC2 -6871
FBXO21 -6888
B3GNT7 -6908
UBE2Z -6951
MUC20 -6993
RABGGTB -7020
TRAPPC2 -7043
COG1 -7045
ALG9 -7052
CAND1 -7058
NUP155 -7061
MGAT4A -7072
EEF2KMT -7078
FBXW4 -7094
PCNA -7101
NUP54 -7131
B3GNT9 -7144
POMGNT1 -7185
UBE2T -7197
MDC1 -7222
NR2C1 -7255
WDR48 -7288
ALG10B -7293
UAP1 -7325
PSME2 -7327
B4GAT1 -7331
ACTL6A -7372
POMT1 -7414
LYPD3 -7429
POFUT2 -7461
TRAF2 -7465
PSMA5 -7476
IFIH1 -7494
DDX58 -7512
NUP205 -7516
ADAMTSL5 -7525
ACTR5 -7529
TRAF3 -7539
DCAF13 -7564
STAMBPL1 -7591
MXRA8 -7619
ENGASE -7636
TRIM28 -7684
NSMCE3 -7693
PIGK -7714
IGFBP3 -7733
SIN3A -7740
ANK3 -7751
USP11 -7759
HLTF -7766
PSME1 -7778
SEC22A -7808
SAE1 -7842
KLHL5 -7844
PGAP1 -7851
COMMD6 -7862
SMAD3 -7868
UCHL5 -7902
EIF5A2 -7913
ST6GALNAC1 -7918
EID3 -7921
B3GNT3 -7945
NUP188 -7953
SPRN -7988
PIGL -8009
STX17 -8013
AGBL3 -8031
SUMF2 -8041
TAF9B -8058
DCAF16 -8064
RUVBL1 -8098
SPTBN1 -8138
TP53BP1 -8162
DPH1 -8186
RNF144A -8265
KLHL22 -8266
NUP107 -8285
BMI1 -8355
L3MBTL2 -8356
NUP160 -8357
NUP43 -8368
RAB39B -8372
NSMCE4A -8381
RBBP7 -8382
PARP1 -8391
POLB -8449
TOMM70 -8486
PSMB9 -8503
LMAN1 -8522
KCTD7 -8523
ST6GAL1 -8538
AXIN2 -8546
MPI -8555
GALNT12 -8573
PHC1 -8578
RANGAP1 -8592
ASXL1 -8665
RAB30 -8666
MAT2B -8690
USP20 -8718
UBA2 -8752
BMP4 -8762
RTN4RL1 -8820
COPS8 -8830
TUBB4A -8884
LARGE1 -8905
DCAF17 -8935
ZNF131 -8936
SCMH1 -8966
SPON1 -8990
SATB1 -8992
PIGU -9021
KAT2A -9063
CASP8AP2 -9120
NAE1 -9125
HSPA8 -9129
RECK -9151
TP53 -9170
DNAJC24 -9187
RORA -9193
KLHL25 -9211
FOLR2 -9231
ST8SIA1 -9250
MYC -9357
NUB1 -9383
RAB40B -9391
TOMM20 -9392
CUL1 -9420
SPTAN1 -9461
WRN -9501
UBE2Q2 -9504
GALNT9 -9509
SEMA5A -9520
UBE2G2 -9540
TRAPPC6A -9543
SEH1L -9574
DCUN1D4 -9585
RPS2 -9591
LMO7 -9595
DPH2 -9620
DNMT1 -9624
NUP88 -9668
FBXO32 -9702
RPS27A -9723
FBXO31 -9725
NUP35 -9726
DCAF4 -9743
EEF1A1 -9751
PIGW -9767
RPA1 -9799
NR3C2 -9803
FBXO4 -9825
MAN1C1 -9944
CYLD -9961
ARSK -10007
NOP58 -10031
KLHL3 -10032
FN3KRP -10037
BIRC3 -10039
RAD18 -10057
GATA3 -10071
NDC1 -10077
FBXL16 -10105
NPM1 -10121
GNPNAT1 -10125
GCNT4 -10137


Translocation of ZAP-70 to Immunological synapse

Translocation of ZAP-70 to Immunological synapse
1276
set Translocation of ZAP-70 to Immunological synapse
setSize 24
pANOVA 1.98e-09
s.dist -0.707
p.adjustANOVA 5.09e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
TRBV12-3 -9971
TRAC -9703
HLA-DQB2 -9656
LCK -9556
TRBC1 -9303
TRAV29DV5 -9278
CD3E -9249
TRAV19 -9248
HLA-DRA -9006
HLA-DQA2 -8774
ZAP70 -8755
CD247 -8741
HLA-DPB1 -8397
TRBV7-9 -8303
CD3D -8297
HLA-DPA1 -8217
CD3G -8111
CD4 -6881
HLA-DQA1 -6389
TRAV8-4 -4769

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TRBV12-3 -9971
TRAC -9703
HLA-DQB2 -9656
LCK -9556
TRBC1 -9303
TRAV29DV5 -9278
CD3E -9249
TRAV19 -9248
HLA-DRA -9006
HLA-DQA2 -8774
ZAP70 -8755
CD247 -8741
HLA-DPB1 -8397
TRBV7-9 -8303
CD3D -8297
HLA-DPA1 -8217
CD3G -8111
CD4 -6881
HLA-DQA1 -6389
TRAV8-4 -4769
HLA-DQB1 -4459
HLA-DRB1 -334
HLA-DRB5 748
PTPN22 6966


Signaling by Rho GTPases

Signaling by Rho GTPases
1131
set Signaling by Rho GTPases
setSize 367
pANOVA 2.45e-09
s.dist 0.181
p.adjustANOVA 6.19e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2AJ 11447
ARHGEF11 11412
GMIP 11339
WASF1 11328
CTNNA1 11326
NCKAP1L 11304
RHOU 11282
DLC1 11274
ABR 11251
MAPK1 11193
S100A8 11184
PRKCD 11168
PLEKHG2 11117
MAPK14 11115
ARHGAP29 11104
RHOT1 11096
ARHGAP26 11079
ARHGAP27 10993
ARPC1A 10981
FMNL2 10945

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2AJ 11447.0
ARHGEF11 11412.0
GMIP 11339.0
WASF1 11328.0
CTNNA1 11326.0
NCKAP1L 11304.0
RHOU 11282.0
DLC1 11274.0
ABR 11251.0
MAPK1 11193.0
S100A8 11184.0
PRKCD 11168.0
PLEKHG2 11117.0
MAPK14 11115.0
ARHGAP29 11104.0
RHOT1 11096.0
ARHGAP26 11079.0
ARHGAP27 10993.0
ARPC1A 10981.0
FMNL2 10945.0
BTK 10849.0
MYO9B 10832.0
MRTFA 10825.0
NCF4 10813.0
WASF2 10807.0
NCF2 10793.0
PREX1 10783.0
ARPC1B 10781.0
SRGAP2 10779.0
WAS 10777.0
ARAP1 10740.0
ITSN1 10737.0
GRB2 10733.0
CLIP1 10646.0
RHOG 10635.0
RAC1 10624.0
S100A9 10613.0
ACTB 10606.0
FGD4 10532.0
FGD2 10505.0
YWHAG 10453.0
ARHGAP1 10447.0
DVL3 10441.0
ARHGEF40 10425.0
CYFIP1 10420.0
NDEL1 10403.0
ARHGAP24 10317.0
VAV1 10226.0
MYL6 10185.0
CYBA 10173.0
ARAP3 10157.0
ARPC5 10102.0
YWHAH 10050.0
ARHGDIB 10049.0
PAK1 10043.0
IQGAP1 10037.0
SRGAP1 9993.0
PPP2R5B 9913.0
ARHGAP19 9828.0
PPP2R5A 9827.0
DLG4 9813.0
ARHGEF2 9798.0
CFL1 9794.0
MAPK3 9750.0
SOS2 9744.0
ARHGAP9 9702.0
H2BC21 9690.0
LIMK2 9689.0
ACTG1 9678.0
CTNNB1 9670.0
CYBB 9660.0
DIAPH2 9644.0
ARPC4 9592.0
RHOA 9401.0
ABI1 9373.0
OCRL 9323.0
H2BC12 9280.0
FMNL1 9262.0
SRF 9254.0
MYH9 9224.0
PAK2 9042.0
TAX1BP3 9041.0
ARPC2 9016.0
H3-3A 8985.0
ARHGAP18 8978.0
YWHAE 8971.0
ARHGEF17 8963.0
H3C15 8929.5
H2BC4 8925.0
ARHGAP30 8914.0
ACTR2 8895.0
H2AC20 8893.0
KLC1 8888.0
ACTR3 8873.0
NCKAP1 8861.0
FGD3 8856.0
ARPC3 8726.0
B9D2 8721.0
PDPK1 8710.0
WIPF2 8699.0
ROCK1 8695.0
MYH10 8632.0
AKAP13 8579.0
PRKCB 8577.0
PPP1R12B 8489.0
IQGAP2 8437.0
VAV3 8413.0
PFN1 8397.0
CDC42 8342.0
FLNA 8318.0
DYNC1LI1 8276.0
RAC2 8237.0
KIF5B 8197.0
ARHGDIA 8065.0
LIMK1 8062.0
TAOK1 7977.0
RHOB 7921.0
FAM13A 7917.0
NCOA2 7898.0
MAPRE1 7885.0
PAFAH1B1 7857.0
PPP1R12A 7801.0
GDI1 7789.0
STARD8 7731.0
DYNC1LI2 7644.0
SEC13 7506.0
ARHGAP23 7484.0
PPP2CB 7451.0
MCF2 7407.0
ARHGEF37 7406.0
ARHGAP28 7309.0
NCF1 7245.0
RALBP1 7224.0
DIAPH1 7128.0
CLASP1 6986.0
GDI2 6949.0
NSL1 6874.0
PPP2CA 6806.0
H2BC5 6759.0
PPP1CB 6745.0
DYNC1I2 6705.0
CENPO 6682.0
AR 6643.0
ROCK2 6611.0
PPP2R5D 6601.0
ARHGAP44 6572.0
PIK3R2 6511.0
KLC3 6451.0
PKN1 6333.0
H2BC17 6188.0
ARHGAP31 6165.0
ABL1 6127.0
H2BC11 6121.0
CENPE 5930.0
RACGAP1 5897.0
NUP98 5874.0
CDC25C 5800.0
KIF14 5707.0
MYL12B 5703.0
CHN2 5539.0
H2AC6 5440.0
PLK1 5400.0
ARHGAP11B 5391.0
GNA13 5302.0
YWHAZ 5202.0
PPP2R1A 5189.0
TRIO 4828.0
RHOBTB1 4769.0
YWHAB 4721.0
CDC20 4670.0
RHOC 4639.0
KLK2 4578.0
CENPF 4564.0
BIRC5 4541.0
ARHGAP4 4490.0
NDE1 4430.0
STARD13 4392.0
H2AZ1 4378.0
ARHGAP6 4353.0
ECT2 4330.0
ARHGEF12 4165.0
NF2 4139.0
INCENP 3884.0
DEPDC1B 3627.0
SKA1 3453.0
RCC2 3388.0
ERCC6L 3386.0
ARHGAP11A 3359.0
WASL 3297.0
TIAM2 3254.0
WIPF1 3137.0
CIT 3097.0
CFTR 3091.0
KNL1 3066.0
ARHGAP25 3004.0
ARHGEF6 2908.0
PKN3 2892.0
DYNC1I1 2879.0
CKAP5 2872.0
RHOQ 2797.0
VAV2 2755.0
SPC24 2754.0
SGO1 2692.0
H2BC15 2474.0
CENPA 2464.0
SRGAP3 2421.0
PRC1 2399.0
KIF2C 2011.0
AURKB 1985.0
MYL9 1931.0
MAD1L1 1882.0
SFN 1840.0
DYNC1H1 1705.0
DYNLL1 1530.0
BCR 1529.0
ARHGEF1 1282.0
MYLK 1267.0
IQGAP3 1051.0
BUB1 1004.0
ARHGAP21 976.0
CENPP 687.0
PIN1 577.0
PPP1CC 519.0
CTTN 514.0
PKN2 418.0
PTK2 388.0
CDCA8 310.0
H2BU1 298.0
OPHN1 294.0
RHPN2 262.0
PPP2R1B 89.0
ARHGEF26 -56.0
AHCTF1 -241.0
CENPI -272.0
CDH1 -307.0
KIF18A -394.0
ARHGEF7 -477.0
ZW10 -627.0
CYFIP2 -775.0
PMF1 -800.0
ARHGAP12 -877.0
LIN7B -933.0
DIAPH3 -961.0
ARHGEF38 -1061.0
RANBP2 -1141.0
CENPN -1151.0
CALM1 -1245.0
WASF3 -1364.0
ARHGAP33 -1659.0
PIK3C3 -1718.0
INPP5B -1747.0
BAIAP2 -1877.0
CLASP2 -1947.0
NUF2 -1978.0
PIK3R4 -2097.0
A2M -2133.0
ARHGAP35 -2201.0
RHOT2 -2229.0
MYH11 -2243.0
NUP37 -2275.0
KTN1 -2306.0
MYO9A -2406.0
PRKCA -2408.0
BRK1 -2561.0
PPP2R5E -2595.0
ARHGEF10 -2615.0
RAC3 -2651.0
BUB1B -2766.0
DEPDC7 -2922.0
SOS1 -2983.0
ARHGEF18 -3061.0
ITGB1 -3073.0
CDKN1B -3127.0
ARAP2 -3156.0
DAAM1 -3188.0
XPO1 -3214.0
KDM4C -3380.0
PPP1R14A -3415.0
NUP85 -3427.0
ARHGAP22 -3431.0
TIAM1 -3517.0
ARHGAP8 -3552.0
NCKIPSD -3692.0
ARHGAP39 -4144.0
KLC4 -4248.0
CENPL -4320.0
ZWINT -4458.0
CENPU -4507.0
YWHAQ -4624.0
DVL1 -4637.0
MAPK11 -4641.0
ZWILCH -4661.0
NUDC -4710.0
ARHGEF35 -4866.0
DYNLL2 -4904.0
NOXA1 -4914.0
ARHGAP15 -5079.0
PPP2R5C -5198.0
CENPC -5210.0
DSN1 -5307.0
NUP133 -5346.0
MEN1 -5364.0
KLC2 -5453.0
SKA2 -5481.0
SGO2 -5502.0
H2AZ2 -5576.0
DVL2 -5637.0
ARHGEF9 -5671.0
ARHGEF39 -5711.0
H2BC9 -5728.0
PAK3 -5908.0
SCAI -5942.0
NDC80 -5999.0
PRKCZ -6016.0
TRIP10 -6094.0
FAM13B -6151.0
SRC -6396.0
KNTC1 -6520.0
ARHGAP17 -6549.0
CENPK -6671.0
KIF2A -6844.0
ARHGAP10 -6902.0
KIF5A -6961.0
CENPQ -7019.0
ARHGAP42 -7129.0
RHOBTB2 -7166.0
MCF2L -7236.0
KDM1A -7314.0
CENPT -7317.0
ARHGAP32 -7436.0
GOPC -7500.0
NET1 -7666.0
MAD2L1 -7701.0
KALRN -8077.0
FMNL3 -8078.0
ABI2 -8174.0
ITGB3BP -8253.0
NUP107 -8285.0
NUP160 -8357.0
NUP43 -8368.0
ARHGEF3 -8386.0
ARHGEF5 -8463.0
CENPM -8484.0
CHN1 -8566.0
RANGAP1 -8592.0
OBSCN -8610.0
MIS12 -8664.0
RHOF -8679.0
ARHGEF19 -8770.0
ARHGEF10L -8789.0
NCK1 -8975.0
PFN2 -9148.0
ARHGEF4 -9155.0
RPS27 -9175.0
RHOH -9236.0
CENPH -9281.0
RHPN1 -9389.0
SPDL1 -9495.0
SYDE2 -9555.0
EVL -9560.0
RASGRF2 -9563.0
SEH1L -9574.0
BUB3 -9608.0
PLEKHG5 -9612.0
ARHGAP5 -9887.0
TAGAP -10011.0
RTKN -10047.0


Mitochondrial translation

Mitochondrial translation
667
set Mitochondrial translation
setSize 97
pANOVA 2.66e-09
s.dist -0.35
p.adjustANOVA 6.59e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
MRPS6 -9838
GFM1 -9467
MRPS33 -9440
MRPL50 -9302
MRPS25 -9279
MRPS27 -9147
MRPS9 -8917
MRPL48 -8859
MRPL24 -8692
MRPL46 -8479
MRPS30 -8262
MRPS18B -8125
MRPL17 -8047
MRPL32 -7992
MRPL39 -7936
MRPL1 -7594
MRPL38 -7496
MRPS2 -7237
MRPL42 -7224
MRPL9 -7188

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MRPS6 -9838
GFM1 -9467
MRPS33 -9440
MRPL50 -9302
MRPS25 -9279
MRPS27 -9147
MRPS9 -8917
MRPL48 -8859
MRPL24 -8692
MRPL46 -8479
MRPS30 -8262
MRPS18B -8125
MRPL17 -8047
MRPL32 -7992
MRPL39 -7936
MRPL1 -7594
MRPL38 -7496
MRPS2 -7237
MRPL42 -7224
MRPL9 -7188
DAP3 -7087
MRPL45 -6990
MRPS17 -6909
MRPL14 -6728
MRPS14 -6718
MRPS7 -6677
PTCD3 -6500
MRPS21 -6319
MRPS28 -6255
TSFM -6082
MRPL35 -5957
MRPL3 -5916
MRPS12 -5654
MRPL49 -5619
MRPL54 -5616
MRRF -5487
MRPL11 -5474
MRPS26 -5430
MT-RNR1 -5094
MRPL57 -5039
MRPL34 -4765
MRPL43 -4449
MRPL27 -4262
MRPS23 -4230
MRPL19 -4123
MRPL58 -3985
MRPS31 -3868
MRPL12 -3819
MRPL55 -3524
MRPL41 -3438
MRPS35 -3315
MRPL18 -3314
MTIF2 -3020
MRPL40 -2981
MRPL15 -2975
GADD45GIP1 -2813
MRPS10 -2725
MRPL21 -2473
MRPL2 -2449
MRPL30 -2421
MRPS22 -2388
MRPS34 -2208
MRPS18C -2145
MRPL47 -2119
MRPL4 -1924
MRPL16 -1832
MRPL20 -1647
ERAL1 -1389
MRPS15 -924
MRPS36 -492
MRPL22 -462
MT-RNR2 -408
MRPL13 -237
MRPL37 177
MTIF3 221
MRPS16 350
MRPS24 1048
MRPS18A 1407
GFM2 1540
MRPL36 1646
OXA1L 1825
MRPL44 1847
MRPS11 2087
MRPS5 2484
MRPL51 2595
MRPL33 2637
MT-TV 3363
TUFM 3457
CHCHD1 3643
MRPL52 4004
MRPL10 4156
MTFMT 4587
MRPL23 4865
MTRF1L 5386
AURKAIP1 5758
MRPL53 6626
MRPL28 9785


Activation of the pre-replicative complex

Activation of the pre-replicative complex
50
set Activation of the pre-replicative complex
setSize 32
pANOVA 2.71e-09
s.dist -0.607
p.adjustANOVA 6.59e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
MCM3 -9943
POLA1 -9841
RPA1 -9799
MCM7 -9325
POLE3 -9287
RPA3 -9220
PRIM1 -9166
DBF4 -8907
MCM6 -8631
ORC5 -8539
ORC2 -8256
POLA2 -7950
ORC3 -7889
POLE2 -7763
PRIM2 -7112
MCM4 -7086
MCM2 -6880
ORC4 -6267
MCM8 -5713
CDC45 -5132

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MCM3 -9943
POLA1 -9841
RPA1 -9799
MCM7 -9325
POLE3 -9287
RPA3 -9220
PRIM1 -9166
DBF4 -8907
MCM6 -8631
ORC5 -8539
ORC2 -8256
POLA2 -7950
ORC3 -7889
POLE2 -7763
PRIM2 -7112
MCM4 -7086
MCM2 -6880
ORC4 -6267
MCM8 -5713
CDC45 -5132
RPA2 -4811
MCM10 -4587
CDC7 -4493
POLE -4081
CDK2 -3614
CDT1 -3436
ORC1 -2973
MCM5 -2327
POLE4 -1856
CDC6 -1597
GMNN 2164
ORC6 5337


Mitochondrial translation termination

Mitochondrial translation termination
670
set Mitochondrial translation termination
setSize 91
pANOVA 3.55e-09
s.dist -0.358
p.adjustANOVA 8.47e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
MRPS6 -9838
MRPS33 -9440
MRPL50 -9302
MRPS25 -9279
MRPS27 -9147
MRPS9 -8917
MRPL48 -8859
MRPL24 -8692
MRPL46 -8479
MRPS30 -8262
MRPS18B -8125
MRPL17 -8047
MRPL32 -7992
MRPL39 -7936
MRPL1 -7594
MRPL38 -7496
MRPS2 -7237
MRPL42 -7224
MRPL9 -7188
DAP3 -7087

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MRPS6 -9838
MRPS33 -9440
MRPL50 -9302
MRPS25 -9279
MRPS27 -9147
MRPS9 -8917
MRPL48 -8859
MRPL24 -8692
MRPL46 -8479
MRPS30 -8262
MRPS18B -8125
MRPL17 -8047
MRPL32 -7992
MRPL39 -7936
MRPL1 -7594
MRPL38 -7496
MRPS2 -7237
MRPL42 -7224
MRPL9 -7188
DAP3 -7087
MRPL45 -6990
MRPS17 -6909
MRPL14 -6728
MRPS14 -6718
MRPS7 -6677
PTCD3 -6500
MRPS21 -6319
MRPS28 -6255
MRPL35 -5957
MRPL3 -5916
MRPS12 -5654
MRPL49 -5619
MRPL54 -5616
MRRF -5487
MRPL11 -5474
MRPS26 -5430
MT-RNR1 -5094
MRPL57 -5039
MRPL34 -4765
MRPL43 -4449
MRPL27 -4262
MRPS23 -4230
MRPL19 -4123
MRPL58 -3985
MRPS31 -3868
MRPL12 -3819
MRPL55 -3524
MRPL41 -3438
MRPS35 -3315
MRPL18 -3314
MRPL40 -2981
MRPL15 -2975
GADD45GIP1 -2813
MRPS10 -2725
MRPL21 -2473
MRPL2 -2449
MRPL30 -2421
MRPS22 -2388
MRPS34 -2208
MRPS18C -2145
MRPL47 -2119
MRPL4 -1924
MRPL16 -1832
MRPL20 -1647
ERAL1 -1389
MRPS15 -924
MRPS36 -492
MRPL22 -462
MT-RNR2 -408
MRPL13 -237
MRPL37 177
MRPS16 350
MRPS24 1048
MRPS18A 1407
GFM2 1540
MRPL36 1646
OXA1L 1825
MRPL44 1847
MRPS11 2087
MRPS5 2484
MRPL51 2595
MRPL33 2637
MT-TV 3363
CHCHD1 3643
MRPL52 4004
MRPL10 4156
MRPL23 4865
MTRF1L 5386
AURKAIP1 5758
MRPL53 6626
MRPL28 9785


Mitochondrial translation initiation

Mitochondrial translation initiation
669
set Mitochondrial translation initiation
setSize 91
pANOVA 3.68e-09
s.dist -0.358
p.adjustANOVA 8.63e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
MRPS6 -9838
MRPS33 -9440
MRPL50 -9302
MRPS25 -9279
MRPS27 -9147
MRPS9 -8917
MRPL48 -8859
MRPL24 -8692
MRPL46 -8479
MRPS30 -8262
MRPS18B -8125
MRPL17 -8047
MRPL32 -7992
MRPL39 -7936
MRPL1 -7594
MRPL38 -7496
MRPS2 -7237
MRPL42 -7224
MRPL9 -7188
DAP3 -7087

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MRPS6 -9838
MRPS33 -9440
MRPL50 -9302
MRPS25 -9279
MRPS27 -9147
MRPS9 -8917
MRPL48 -8859
MRPL24 -8692
MRPL46 -8479
MRPS30 -8262
MRPS18B -8125
MRPL17 -8047
MRPL32 -7992
MRPL39 -7936
MRPL1 -7594
MRPL38 -7496
MRPS2 -7237
MRPL42 -7224
MRPL9 -7188
DAP3 -7087
MRPL45 -6990
MRPS17 -6909
MRPL14 -6728
MRPS14 -6718
MRPS7 -6677
PTCD3 -6500
MRPS21 -6319
MRPS28 -6255
MRPL35 -5957
MRPL3 -5916
MRPS12 -5654
MRPL49 -5619
MRPL54 -5616
MRPL11 -5474
MRPS26 -5430
MT-RNR1 -5094
MRPL57 -5039
MRPL34 -4765
MRPL43 -4449
MRPL27 -4262
MRPS23 -4230
MRPL19 -4123
MRPL58 -3985
MRPS31 -3868
MRPL12 -3819
MRPL55 -3524
MRPL41 -3438
MRPS35 -3315
MRPL18 -3314
MTIF2 -3020
MRPL40 -2981
MRPL15 -2975
GADD45GIP1 -2813
MRPS10 -2725
MRPL21 -2473
MRPL2 -2449
MRPL30 -2421
MRPS22 -2388
MRPS34 -2208
MRPS18C -2145
MRPL47 -2119
MRPL4 -1924
MRPL16 -1832
MRPL20 -1647
ERAL1 -1389
MRPS15 -924
MRPS36 -492
MRPL22 -462
MT-RNR2 -408
MRPL13 -237
MRPL37 177
MTIF3 221
MRPS16 350
MRPS24 1048
MRPS18A 1407
MRPL36 1646
OXA1L 1825
MRPL44 1847
MRPS11 2087
MRPS5 2484
MRPL51 2595
MRPL33 2637
MT-TV 3363
CHCHD1 3643
MRPL52 4004
MRPL10 4156
MTFMT 4587
MRPL23 4865
AURKAIP1 5758
MRPL53 6626
MRPL28 9785


EPH-Ephrin signaling

EPH-Ephrin signaling
320
set EPH-Ephrin signaling
setSize 79
pANOVA 2.09e-08
s.dist 0.365
p.adjustANOVA 4.82e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
NCSTN 11452
AP2A1 11340
MMP2 11162
ARPC1A 10981
MMP9 10920
LYN 10810
ARPC1B 10781
ITSN1 10737
RAC1 10624
ACTB 10606
PSEN1 10429
CLTC 10304
AP2A2 10223
MYL6 10185
ARPC5 10102
PAK1 10043
ADAM10 9992
SDCBP 9947
CFL1 9794
LIMK2 9689

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NCSTN 11452
AP2A1 11340
MMP2 11162
ARPC1A 10981
MMP9 10920
LYN 10810
ARPC1B 10781
ITSN1 10737
RAC1 10624
ACTB 10606
PSEN1 10429
CLTC 10304
AP2A2 10223
MYL6 10185
ARPC5 10102
PAK1 10043
ADAM10 9992
SDCBP 9947
CFL1 9794
LIMK2 9689
ACTG1 9678
ARPC4 9592
APH1B 9474
RHOA 9401
MYH9 9224
CLTCL1 9201
PAK2 9042
ARPC2 9016
ACTR2 8895
ACTR3 8873
EPHB3 8814
AP2M1 8799
ARPC3 8726
ROCK1 8695
MYH10 8632
VAV3 8413
CDC42 8342
LIMK1 8062
AP2S1 8045
CLTB 7968
CLTA 7164
PSENEN 7091
ROCK2 6611
EPHB2 6490
RASA1 6250
DNM1 5998
MYL12B 5703
MYL12A 5419
EFNA4 4047
WASL 3297
EPHB4 3175
AP2B1 2910
VAV2 2755
APH1A 2563
ARHGEF28 2384
SDC2 2325
MYL9 1931
EFNA5 836
PTK2 388
EPHB1 -21
ARHGEF7 -477
MYH11 -2243
EFNA1 -2266
YES1 -2846
NCK2 -2908
TIAM1 -3517
EPHA2 -3903
EFNB1 -5205
FYN -5211
HRAS -5273
PAK3 -5908
PSEN2 -6393
SRC -6396
EFNA3 -6702
GIT1 -6848
KALRN -8077
EPHB6 -8593
EPHA1 -9433
EPHA4 -10147


COPI-mediated anterograde transport

COPI-mediated anterograde transport
132
set COPI-mediated anterograde transport
setSize 78
pANOVA 2.88e-08
s.dist 0.363
p.adjustANOVA 6.53e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
COPG1 11142
CD55 10914
DCTN4 10682
ARF1 10610
COPA 10521
DCTN2 10412
ACTR1A 10310
RAB1B 10055
COG7 9987
RAB1A 9971
NSF 9870
GORASP1 9633
KDELR1 9613
CAPZB 9575
DCTN1 9558
CAPZA1 9530
ARF3 9465
GOLGA2 9412
ARF4 9348
COPB2 8898

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
COPG1 11142
CD55 10914
DCTN4 10682
ARF1 10610
COPA 10521
DCTN2 10412
ACTR1A 10310
RAB1B 10055
COG7 9987
RAB1A 9971
NSF 9870
GORASP1 9633
KDELR1 9613
CAPZB 9575
DCTN1 9558
CAPZA1 9530
ARF3 9465
GOLGA2 9412
ARF4 9348
COPB2 8898
COPG2 8709
STX5 8547
COG4 8402
ARF5 8313
DYNC1LI1 8276
COPE 8230
CAPZA2 8225
TMED9 8028
COPB1 7997
SPTB 7702
GBF1 7683
DYNC1LI2 7644
YKT6 7621
DCTN6 7540
NAPG 7516
ARFGAP3 7424
ARCN1 6965
DYNC1I2 6705
NAPA 6660
DCTN3 6625
KDELR2 6387
TMEM115 6183
GOSR2 5986
ACTR10 5886
ANK1 5655
TMED2 5345
SPTBN5 4732
ARFGAP2 4331
CD59 4252
SPTA1 4063
TMED7 3978
TMED3 3420
NAPB 3180
ARFGAP1 2978
DYNC1I1 2879
USO1 2424
COG5 2352
DYNC1H1 1705
DYNLL1 1530
KDELR3 869
COPZ1 412
COG8 406
DCTN5 297
SPTBN2 -220
BET1L -1574
COG3 -2175
GOSR1 -3080
GOLGB1 -4004
TMED10 -4413
DYNLL2 -4904
COG2 -5554
COPZ2 -5974
BET1 -6342
COG6 -6645
COG1 -7045
ANK3 -7751
SPTBN1 -8138
SPTAN1 -9461


RHO GTPases Activate WASPs and WAVEs

RHO GTPases Activate WASPs and WAVEs
887
set RHO GTPases Activate WASPs and WAVEs
setSize 35
pANOVA 3.78e-08
s.dist 0.537
p.adjustANOVA 8.44e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
WASF1 11328
NCKAP1L 11304
MAPK1 11193
ARPC1A 10981
BTK 10849
WASF2 10807
ARPC1B 10781
WAS 10777
GRB2 10733
RAC1 10624
ACTB 10606
CYFIP1 10420
ARPC5 10102
MAPK3 9750
ACTG1 9678
ARPC4 9592
ABI1 9373
ARPC2 9016
ACTR2 8895
ACTR3 8873

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
WASF1 11328
NCKAP1L 11304
MAPK1 11193
ARPC1A 10981
BTK 10849
WASF2 10807
ARPC1B 10781
WAS 10777
GRB2 10733
RAC1 10624
ACTB 10606
CYFIP1 10420
ARPC5 10102
MAPK3 9750
ACTG1 9678
ARPC4 9592
ABI1 9373
ARPC2 9016
ACTR2 8895
ACTR3 8873
NCKAP1 8861
ARPC3 8726
WIPF2 8699
CDC42 8342
ABL1 6127
WASL 3297
WIPF1 3137
PTK2 388
CYFIP2 -775
WASF3 -1364
BAIAP2 -1877
BRK1 -2561
NCKIPSD -3692
ABI2 -8174
NCK1 -8975


DNA strand elongation

DNA strand elongation
245
set DNA strand elongation
setSize 32
pANOVA 4.6e-08
s.dist -0.558
p.adjustANOVA 1.01e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
POLD2 -10054
MCM3 -9943
POLA1 -9841
RPA1 -9799
LIG1 -9469
RFC3 -9405
MCM7 -9325
RPA3 -9220
PRIM1 -9166
RFC4 -8897
MCM6 -8631
GINS4 -8275
POLA2 -7950
RFC5 -7574
PRIM2 -7112
PCNA -7101
MCM4 -7086
MCM2 -6880
FEN1 -6485
DNA2 -6307

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
POLD2 -10054
MCM3 -9943
POLA1 -9841
RPA1 -9799
LIG1 -9469
RFC3 -9405
MCM7 -9325
RPA3 -9220
PRIM1 -9166
RFC4 -8897
MCM6 -8631
GINS4 -8275
POLA2 -7950
RFC5 -7574
PRIM2 -7112
PCNA -7101
MCM4 -7086
MCM2 -6880
FEN1 -6485
DNA2 -6307
MCM8 -5713
CDC45 -5132
RFC1 -5080
RPA2 -4811
GINS3 -3875
GINS2 -3476
POLD1 -2573
MCM5 -2327
GINS1 4263
RFC2 5478
POLD4 9079
POLD3 10698


Rab regulation of trafficking

Rab regulation of trafficking
931
set Rab regulation of trafficking
setSize 121
pANOVA 4.86e-08
s.dist 0.287
p.adjustANOVA 1.05e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
RIN1 11169
ULK1 11151
SBF2 11135
TBC1D14 11112
DENND3 11024
RAB10 10956
TBC1D2 10799
RIN2 10772
RAB31 10661
RAB32 10626
RAB13 10611
MON1B 10423
TBC1D10B 10419
RAB39A 10255
RAB7A 10115
RAB1B 10055
RAB1A 9971
RAB6A 9958
RAB5C 9864
DENND5A 9804

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RIN1 11169
ULK1 11151
SBF2 11135
TBC1D14 11112
DENND3 11024
RAB10 10956
TBC1D2 10799
RIN2 10772
RAB31 10661
RAB32 10626
RAB13 10611
MON1B 10423
TBC1D10B 10419
RAB39A 10255
RAB7A 10115
RAB1B 10055
RAB1A 9971
RAB6A 9958
RAB5C 9864
DENND5A 9804
TRAPPC12 9770
RAB27A 9628
TRAPPC1 9087
YWHAE 8971
DENND4B 8934
RAB3IL1 8870
HPS1 8846
GAPVD1 8844
GGA3 8491
RAB5B 8258
TBC1D13 8195
RABGEF1 8058
MAP1LC3B 8019
GDI1 7789
RAB8B 7739
TRAPPC8 7708
RIC1 7660
DENND2C 7658
GABARAPL2 7529
RAB35 7522
TRAPPC11 7513
ALS2 7445
RGP1 7355
DENND1A 7260
RAB5A 7154
GGA1 7102
GABARAP 7075
TBC1D7 7042
RAB18 7038
GDI2 6949
RAB11A 6617
RAB3GAP2 6599
TRAPPC9 6548
AKT1 6498
RAB3A 6284
ANKRD27 6228
RAB21 6196
RAB7B 6060
CCZ1 5832
RABGAP1 5785
TBC1D16 5645
TBC1D24 5578
RAB8A 5522
AKT2 5502
RAB14 5469
CCZ1B 5430
RAB3GAP1 5167
RAB33B 5028
TRAPPC3 4443
TSC2 4311
RAB11B 3969
TBC1D20 3947
TRAPPC5 3257
MADD 3143
ARF6 3007
TRAPPC10 2565
DENND1C 2358
TBC1D25 2205
TSC1 1403
DENND6A 1376
TRAPPC6B 1327
CHM 1115
POLG 1085
RAB27B 774
MON1A 707
DENND6B 706
RAB33A 620
TBC1D3 561
TRAPPC13 -481
RAB3IP -569
GGA2 -1297
RINL -1455
RAB4A -1669
RAB9A -1713
RAB6B -1849
TRAPPC2L -1855
RAB12 -2139
TRAPPC4 -2490
DENND4A -2494
DENND1B -3163
SBF1 -3176
TBC1D15 -3245
RAB38 -3316
DENND2A -3622
DENND4C -3756
TBC1D10A -3790
RAB9B -4177
TBC1D17 -4327
RABEP1 -4568
SYTL1 -4650
CHML -4951
DENND5B -6013
HPS4 -6635
TRAPPC2 -7043
TBC1D10C -7608
RAB39B -8372
OPTN -8400
AKT3 -8810
DENND2D -9419
TRAPPC6A -9543
ALS2CL -10013


PPARA activates gene expression

PPARA activates gene expression
796
set PPARA activates gene expression
setSize 104
pANOVA 5.5e-08
s.dist 0.308
p.adjustANOVA 1.17e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
PPARG 11451
NCOR2 11217
ACSL1 11102
CD36 10947
CPT2 10925
FADS1 10870
RGL1 10752
MTF1 10630
ME1 10563
NFYC 10461
NCOA6 10326
CARM1 10313
ACOX1 10277
ARNT 10231
RXRA 10073
TXNRD1 9890
SREBF2 9844
PLIN2 9820
EP300 9789
CDK19 9729

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PPARG 11451
NCOR2 11217
ACSL1 11102
CD36 10947
CPT2 10925
FADS1 10870
RGL1 10752
MTF1 10630
ME1 10563
NFYC 10461
NCOA6 10326
CARM1 10313
ACOX1 10277
ARNT 10231
RXRA 10073
TXNRD1 9890
SREBF2 9844
PLIN2 9820
EP300 9789
CDK19 9729
SP1 9699
APOA2 9687
NR1H2 9521
MED13L 9444
FDFT1 9429
FAM120B 9384
ESRRA 9192
HMGCR 9117
MED20 8757
MED8 8643
MED18 8563
ALAS1 8407
NCOA3 8176
NCOR1 8153
CREBBP 8143
MED25 8136
NCOA2 7898
TBL1X 7764
MED12 7718
SMARCD3 7698
FHL2 7159
ARNTL 6905
NCOA1 6885
HELZ2 6747
NFYA 6667
ANGPTL4 6584
MED26 6537
ABCA1 6506
SLC27A1 5937
MED14 5610
HDAC3 5437
CPT1A 5231
PPARA 4862
TBL1XR1 4852
GLIPR1 4675
THRAP3 4646
CDK8 4340
MED16 4162
TIAM2 3254
MED11 3182
RXRB 2848
MED22 2682
GPS2 2541
TRIB3 2492
SREBF1 2292
MED23 1915
HMGCS1 1443
MED24 1185
MED7 1178
AHR 1155
NR1H3 954
MED13 630
PEX11A 600
MED28 479
CHD9 97
G0S2 17
PPARGC1B -31
NRF1 -105
MED15 -911
MED1 -971
TNFRSF21 -1215
AHRR -1354
ABCB4 -1460
MED9 -1496
PPARGC1A -1762
MED19 -1831
GRHL1 -1905
NPAS2 -1986
MED4 -2264
MED31 -2514
MED17 -2648
MED30 -2845
MED27 -2978
MED21 -3045
MED29 -3703
TGS1 -4316
CLOCK -5087
MED6 -6714
CCNC -6937
ACADM -7323
MED10 -8535
RORA -9193
NR1D1 -9199
NFYB -10059


Metabolism of non-coding RNA

Metabolism of non-coding RNA
643
set Metabolism of non-coding RNA
setSize 53
pANOVA 6.3e-08
s.dist -0.429
p.adjustANOVA 1.3e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
NDC1 -10077
NUP35 -9726
NUP88 -9668
GEMIN4 -9658
NCBP2 -9631
SEH1L -9574
DDX20 -9146
WDR77 -9040
SNRPF -8687
SNRPE -8564
NUP43 -8368
NUP160 -8357
NUP107 -8285
PHAX -8164
NUP188 -7953
CLNS1A -7640
SNRPD2 -7545
NUP205 -7516
GEMIN8 -7368
NUP54 -7131

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NDC1 -10077
NUP35 -9726
NUP88 -9668
GEMIN4 -9658
NCBP2 -9631
SEH1L -9574
DDX20 -9146
WDR77 -9040
SNRPF -8687
SNRPE -8564
NUP43 -8368
NUP160 -8357
NUP107 -8285
PHAX -8164
NUP188 -7953
CLNS1A -7640
SNRPD2 -7545
NUP205 -7516
GEMIN8 -7368
NUP54 -7131
NUP155 -7061
SNRPD1 -6705
NUP93 -6458
SNRPD3 -6352
NUP133 -5346
GEMIN6 -4524
TGS1 -4316
GEMIN5 -4269
SNRPB -4187
NUP42 -4045
NUP210 -3949
SMN1 -3889
TPR -3744
NUP85 -3427
GEMIN2 -3379
AAAS -3332
NUP62 -2410
NUP37 -2275
POM121C -1710
RANBP2 -1141
NCBP1 -942
POM121 -142
GEMIN7 9
NUP153 254
SNRPG 560
PRMT5 1582
SNUPN 1602
NUP50 2638
RAE1 5007
NUP98 5874
SEC13 7506
NUP58 9577
NUP214 10131


snRNP Assembly

snRNP Assembly
1354
set snRNP Assembly
setSize 53
pANOVA 6.3e-08
s.dist -0.429
p.adjustANOVA 1.3e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
NDC1 -10077
NUP35 -9726
NUP88 -9668
GEMIN4 -9658
NCBP2 -9631
SEH1L -9574
DDX20 -9146
WDR77 -9040
SNRPF -8687
SNRPE -8564
NUP43 -8368
NUP160 -8357
NUP107 -8285
PHAX -8164
NUP188 -7953
CLNS1A -7640
SNRPD2 -7545
NUP205 -7516
GEMIN8 -7368
NUP54 -7131

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NDC1 -10077
NUP35 -9726
NUP88 -9668
GEMIN4 -9658
NCBP2 -9631
SEH1L -9574
DDX20 -9146
WDR77 -9040
SNRPF -8687
SNRPE -8564
NUP43 -8368
NUP160 -8357
NUP107 -8285
PHAX -8164
NUP188 -7953
CLNS1A -7640
SNRPD2 -7545
NUP205 -7516
GEMIN8 -7368
NUP54 -7131
NUP155 -7061
SNRPD1 -6705
NUP93 -6458
SNRPD3 -6352
NUP133 -5346
GEMIN6 -4524
TGS1 -4316
GEMIN5 -4269
SNRPB -4187
NUP42 -4045
NUP210 -3949
SMN1 -3889
TPR -3744
NUP85 -3427
GEMIN2 -3379
AAAS -3332
NUP62 -2410
NUP37 -2275
POM121C -1710
RANBP2 -1141
NCBP1 -942
POM121 -142
GEMIN7 9
NUP153 254
SNRPG 560
PRMT5 1582
SNUPN 1602
NUP50 2638
RAE1 5007
NUP98 5874
SEC13 7506
NUP58 9577
NUP214 10131


RHO GTPase Effectors

RHO GTPase Effectors
883
set RHO GTPase Effectors
setSize 250
pANOVA 7.74e-08
s.dist 0.197
p.adjustANOVA 1.57e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2AJ 11447
WASF1 11328
CTNNA1 11326
NCKAP1L 11304
MAPK1 11193
S100A8 11184
PRKCD 11168
MAPK14 11115
ARPC1A 10981
FMNL2 10945
BTK 10849
MRTFA 10825
NCF4 10813
WASF2 10807
NCF2 10793
ARPC1B 10781
SRGAP2 10779
WAS 10777
GRB2 10733
CLIP1 10646

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2AJ 11447.0
WASF1 11328.0
CTNNA1 11326.0
NCKAP1L 11304.0
MAPK1 11193.0
S100A8 11184.0
PRKCD 11168.0
MAPK14 11115.0
ARPC1A 10981.0
FMNL2 10945.0
BTK 10849.0
MRTFA 10825.0
NCF4 10813.0
WASF2 10807.0
NCF2 10793.0
ARPC1B 10781.0
SRGAP2 10779.0
WAS 10777.0
GRB2 10733.0
CLIP1 10646.0
RHOG 10635.0
RAC1 10624.0
S100A9 10613.0
ACTB 10606.0
YWHAG 10453.0
DVL3 10441.0
CYFIP1 10420.0
NDEL1 10403.0
MYL6 10185.0
CYBA 10173.0
ARPC5 10102.0
YWHAH 10050.0
PAK1 10043.0
IQGAP1 10037.0
PPP2R5B 9913.0
PPP2R5A 9827.0
DLG4 9813.0
CFL1 9794.0
MAPK3 9750.0
H2BC21 9690.0
LIMK2 9689.0
ACTG1 9678.0
CTNNB1 9670.0
CYBB 9660.0
DIAPH2 9644.0
ARPC4 9592.0
RHOA 9401.0
ABI1 9373.0
H2BC12 9280.0
FMNL1 9262.0
SRF 9254.0
MYH9 9224.0
PAK2 9042.0
TAX1BP3 9041.0
ARPC2 9016.0
H3-3A 8985.0
YWHAE 8971.0
H3C15 8929.5
H2BC4 8925.0
ACTR2 8895.0
H2AC20 8893.0
KLC1 8888.0
ACTR3 8873.0
NCKAP1 8861.0
ARPC3 8726.0
B9D2 8721.0
PDPK1 8710.0
WIPF2 8699.0
ROCK1 8695.0
MYH10 8632.0
PRKCB 8577.0
PPP1R12B 8489.0
IQGAP2 8437.0
PFN1 8397.0
CDC42 8342.0
FLNA 8318.0
DYNC1LI1 8276.0
RAC2 8237.0
KIF5B 8197.0
LIMK1 8062.0
TAOK1 7977.0
RHOB 7921.0
NCOA2 7898.0
MAPRE1 7885.0
PAFAH1B1 7857.0
PPP1R12A 7801.0
DYNC1LI2 7644.0
SEC13 7506.0
PPP2CB 7451.0
NCF1 7245.0
DIAPH1 7128.0
CLASP1 6986.0
NSL1 6874.0
PPP2CA 6806.0
H2BC5 6759.0
PPP1CB 6745.0
DYNC1I2 6705.0
CENPO 6682.0
AR 6643.0
ROCK2 6611.0
PPP2R5D 6601.0
KLC3 6451.0
PKN1 6333.0
H2BC17 6188.0
ABL1 6127.0
H2BC11 6121.0
CENPE 5930.0
NUP98 5874.0
CDC25C 5800.0
KIF14 5707.0
MYL12B 5703.0
H2AC6 5440.0
PLK1 5400.0
YWHAZ 5202.0
PPP2R1A 5189.0
YWHAB 4721.0
CDC20 4670.0
RHOC 4639.0
KLK2 4578.0
CENPF 4564.0
BIRC5 4541.0
NDE1 4430.0
H2AZ1 4378.0
NF2 4139.0
INCENP 3884.0
SKA1 3453.0
RCC2 3388.0
ERCC6L 3386.0
WASL 3297.0
WIPF1 3137.0
CIT 3097.0
CFTR 3091.0
KNL1 3066.0
PKN3 2892.0
DYNC1I1 2879.0
CKAP5 2872.0
RHOQ 2797.0
SPC24 2754.0
SGO1 2692.0
H2BC15 2474.0
CENPA 2464.0
PRC1 2399.0
KIF2C 2011.0
AURKB 1985.0
MYL9 1931.0
MAD1L1 1882.0
SFN 1840.0
DYNC1H1 1705.0
DYNLL1 1530.0
MYLK 1267.0
IQGAP3 1051.0
BUB1 1004.0
CENPP 687.0
PIN1 577.0
PPP1CC 519.0
CTTN 514.0
PKN2 418.0
PTK2 388.0
CDCA8 310.0
H2BU1 298.0
RHPN2 262.0
PPP2R1B 89.0
AHCTF1 -241.0
CENPI -272.0
CDH1 -307.0
KIF18A -394.0
ZW10 -627.0
CYFIP2 -775.0
PMF1 -800.0
LIN7B -933.0
DIAPH3 -961.0
RANBP2 -1141.0
CENPN -1151.0
CALM1 -1245.0
WASF3 -1364.0
PIK3C3 -1718.0
BAIAP2 -1877.0
CLASP2 -1947.0
NUF2 -1978.0
PIK3R4 -2097.0
MYH11 -2243.0
NUP37 -2275.0
KTN1 -2306.0
PRKCA -2408.0
BRK1 -2561.0
PPP2R5E -2595.0
BUB1B -2766.0
ITGB1 -3073.0
CDKN1B -3127.0
DAAM1 -3188.0
XPO1 -3214.0
KDM4C -3380.0
PPP1R14A -3415.0
NUP85 -3427.0
NCKIPSD -3692.0
KLC4 -4248.0
CENPL -4320.0
ZWINT -4458.0
CENPU -4507.0
YWHAQ -4624.0
DVL1 -4637.0
MAPK11 -4641.0
ZWILCH -4661.0
NUDC -4710.0
DYNLL2 -4904.0
NOXA1 -4914.0
PPP2R5C -5198.0
CENPC -5210.0
DSN1 -5307.0
NUP133 -5346.0
MEN1 -5364.0
KLC2 -5453.0
SKA2 -5481.0
SGO2 -5502.0
H2AZ2 -5576.0
DVL2 -5637.0
H2BC9 -5728.0
PAK3 -5908.0
SCAI -5942.0
NDC80 -5999.0
PRKCZ -6016.0
SRC -6396.0
KNTC1 -6520.0
CENPK -6671.0
KIF2A -6844.0
KIF5A -6961.0
CENPQ -7019.0
KDM1A -7314.0
CENPT -7317.0
GOPC -7500.0
MAD2L1 -7701.0
FMNL3 -8078.0
ABI2 -8174.0
ITGB3BP -8253.0
NUP107 -8285.0
NUP160 -8357.0
NUP43 -8368.0
CENPM -8484.0
RANGAP1 -8592.0
MIS12 -8664.0
NCK1 -8975.0
PFN2 -9148.0
RPS27 -9175.0
CENPH -9281.0
RHPN1 -9389.0
SPDL1 -9495.0
EVL -9560.0
SEH1L -9574.0
BUB3 -9608.0
RTKN -10047.0


Toll-like Receptor Cascades

Toll-like Receptor Cascades
1243
set Toll-like Receptor Cascades
setSize 143
pANOVA 1.03e-07
s.dist 0.258
p.adjustANOVA 2.05e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
MYD88 11331
MAP3K8 11291
ITGAM 11269
CTSB 11250
MAPKAPK3 11249
S100A12 11206
MAPK1 11193
TLR5 11191
S100A8 11184
MAPK14 11115
RPS6KA1 11103
NKIRAS2 11077
RIPK3 11013
MAP2K6 10958
CD36 10947
IRAK3 10909
ITGB2 10861
BTK 10849
TLR8 10847
S100A9 10613

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MYD88 11331
MAP3K8 11291
ITGAM 11269
CTSB 11250
MAPKAPK3 11249
S100A12 11206
MAPK1 11193
TLR5 11191
S100A8 11184
MAPK14 11115
RPS6KA1 11103
NKIRAS2 11077
RIPK3 11013
MAP2K6 10958
CD36 10947
IRAK3 10909
ITGB2 10861
BTK 10849
TLR8 10847
S100A9 10613
TLR2 10535
UNC93B1 10526
MAP2K3 10377
DNM2 10373
CTSL 10288
PLCG2 10244
MAP2K1 10148
TLR1 10059
MAPK7 10035
NOD2 9983
MEF2A 9891
MAPK3 9750
TLR4 9549
CD14 9466
IKBKG 9441
LY96 9322
UBE2D1 9286
PELI3 9118
TLR6 9070
TICAM1 8878
TIRAP 8858
MAPKAPK2 8852
MAPK10 8849
FADD 8785
CHUK 8723
UBE2D3 8641
TANK 8576
DUSP3 8510
IKBKE 8263
IRAK1 7970
TNIP2 7810
MAP2K4 7754
CNPY3 7565
PPP2CB 7451
VRK3 7206
NFKBIB 6845
PPP2CA 6806
TAB3 6655
PPP2R5D 6601
PTPN11 6524
CTSS 6504
MAP3K1 6286
APP 6245
PELI2 6164
UBC 6135
DNM1 5998
FBXW11 5621
NFKBIA 5457
CTSK 5320
PPP2R1A 5189
AGER 4895
TBK1 4856
PELI1 4802
SOCS1 4688
TRAF6 4673
RPS6KA2 4384
TICAM2 4262
IRF7 4132
MAP3K7 4043
DNM3 3523
RIPK1 3206
JUN 3122
NFKB1 2860
FOS 2787
BIRC2 2697
ATF1 2556
ECSIT 2321
TAB2 1975
IKBKB 1759
TAB1 1754
MAP2K7 1550
RBSN 1171
LY86 1163
UBB 1026
RPS6KA3 649
PPP2R1B 89
TLR9 -36
EEA1 -171
RELA -204
ATF2 -657
S100A1 -688
UBE2D2 -801
UBE2V1 -1252
S100B -1351
PIK3C3 -1718
HSP90B1 -1788
UBE2N -2071
PIK3R4 -2097
DUSP4 -2116
RIPK2 -2451
DUSP7 -2452
IRAK2 -2799
DUSP6 -3055
UBA52 -3490
NFKB2 -3527
NOD1 -3652
CTSV -3775
CREB1 -3977
BTRC -4212
MAPK11 -4641
CASP8 -4824
BPI -5410
MAPK9 -5454
ELK1 -5884
CD180 -6005
MEF2C -6025
NKIRAS1 -6234
TLR7 -6272
SKP1 -6297
HMGB1 -6699
IRF3 -6721
SIGIRR -6838
TLR10 -7067
TLR3 -7411
TRAF3 -7539
LGMN -7705
SARM1 -8283
PTPN4 -8389
MAPK8 -8929
RPS6KA5 -9386
CUL1 -9420
RPS27A -9723
BIRC3 -10039


Transport of small molecules

Transport of small molecules
1286
set Transport of small molecules
setSize 557
pANOVA 1.08e-07
s.dist 0.132
p.adjustANOVA 2.12e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
SLC36A1 11465
SLC11A1 11464
ASPH 11394
SLC1A3 11387
PRKACA 11363
SLC9A1 11350
ATP6AP1 11341
AP2A1 11340
SLCO4A1 11330
SLC28A3 11302
ATP6V0A1 11283
AQP9 11273
SLC16A3 11262
SLC6A6 11220
SLC8A1 11210
TCIRG1 11138
TRPM2 11134
ADCY3 11111
SLC22A4 11099
CYB5R1 11052

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SLC36A1 11465
SLC11A1 11464
ASPH 11394
SLC1A3 11387
PRKACA 11363
SLC9A1 11350
ATP6AP1 11341
AP2A1 11340
SLCO4A1 11330
SLC28A3 11302
ATP6V0A1 11283
AQP9 11273
SLC16A3 11262
SLC6A6 11220
SLC8A1 11210
TCIRG1 11138
TRPM2 11134
ADCY3 11111
SLC22A4 11099
CYB5R1 11052
HMOX1 11030
PCSK9 11027
ATP6V0D1 11016
ERLIN2 11011
CA4 10997
ATP6V0C 10995
TTYH3 10990
OS9 10951
FURIN 10905
ANO10 10889
TRPV4 10843
SLC39A8 10820
ATP11A 10791
SLC26A6 10786
CTNS 10744
MCOLN1 10741
GNG5 10721
SLC2A3 10714
SLC15A4 10684
SLCO2B1 10681
ABCB10 10674
MICU1 10648
LDLR 10634
SLC39A1 10601
MCU 10599
SLC15A3 10581
TPCN2 10557
RUNX1 10531
PRKAR1A 10510
ATP8B3 10504
SLC9A8 10474
ALAD 10449
SLC31A1 10444
GNB1 10392
LPL 10391
ATP2A2 10359
HDLBP 10343
CLTC 10304
ERLIN1 10296
GNB2 10282
AP2A2 10223
APOD 10209
ADD1 10204
ATP9B 10146
APOBR 10143
FTL 10101
P4HB 10093
PSMD4 10088
FBXL5 10086
GNG10 10071
BSG 10030
ATP6V1D 9982
SLCO3A1 9927
SLC22A15 9916
ATP6V1C1 9900
SLC43A2 9808
SLC39A7 9799
STEAP3 9786
ATP6V0B 9782
SLC29A1 9772
SLC5A9 9767
BEST1 9725
PLTP 9710
APOA2 9687
RAF1 9686
SLC2A14 9648
PARL 9601
ATP6V1A 9534
NR1H2 9521
ATP6V1B2 9436
SLC12A6 9387
SLC4A2 9354
ATP7B 9291
SLC7A7 9251
WNK1 9204
SLC24A4 9191
SLC35A2 9158
NEDD4L 9088
SLC22A1 9022
CYB5R4 8995
ATP9A 8989
ADCY4 8974
AP2M1 8799
SLC8B1 8767
PSMD9 8766
CYB5R2 8743
SLC36A4 8717
PSME3 8716
TRPM6 8660
ALB 8630
ATP11B 8523
NCEH1 8495
SLCO4C1 8486
PSMB7 8460
TRPM4 8435
ATP6V0E1 8417
ATP13A2 8365
PSMB5 8265
SLC30A1 8236
CA1 8217
RNF185 8206
EMB 8204
ATP6V1E1 8198
SLC66A1 8192
PSMD1 8184
SLC9A9 8171
PSMD2 8139
AP2S1 8045
TRPC4AP 8015
PSMB3 8005
CLCN1 8003
ABCD1 7994
STOM 7990
AQP1 7985
ATP2C1 7982
SEL1L 7883
SLC15A2 7881
BEST3 7880
ATP11C 7843
PSMA7 7840
SLC1A2 7827
SRI 7820
ATP2B4 7814
VCP 7804
SLC17A7 7795
OSTM1 7779
PSMD11 7775
PSMD5 7646
NEDD8 7558
SLC4A1 7532
PEX19 7499
ABCA6 7495
SLC29A3 7461
YME1L1 7453
PRKAR2A 7426
SLC6A1 7416
PSMB6 7399
ADCY7 7390
PSMD6 7307
SLC12A4 7279
SLC22A5 7274
TTYH1 7183
CLTA 7164
BSND 7130
ABCC3 7122
ATP6V1H 7104
GNB4 7078
ATP2C2 7061
AQP10 7045
CLCN5 7028
RHAG 7023
SLC3A2 7012
ABCA7 6929
SLC16A7 6924
SLC25A18 6901
UNC79 6897
SAR1B 6893
BMP1 6888
ANO8 6886
FTH1 6883
PSMD12 6820
SLC35B4 6797
NIPA2 6774
HBB 6697
FXYD6 6669
SOAT1 6664
RAB11A 6617
ANGPTL4 6584
CLCN6 6549
ABCA1 6506
MBTPS1 6492
SLC44A1 6488
ABCC10 6464
SLC1A7 6450
SLC35D2 6406
CLCN3 6351
CUTC 6309
ATP1B3 6301
VLDLR 6242
HBA1 6237
TSC22D3 6201
UBC 6135
ABCC9 6129
PCSK5 6103
ATP7A 5970
GNAS 5944
SLC27A1 5937
ABCA9 5833
DMTN 5804
PSMD8 5687
SCNN1A 5680
PRKAR1B 5653
UNC80 5646
NIPAL4 5463
ABCC1 5410
FKBP1B 5387
ATP8B4 5252
PSMA6 5209
SLC9A6 5203
SLC44A2 5180
SLC4A8 5110
SLC7A5 5072
SLC35C1 5026
PSMC6 4959
PDZD11 4944
SLC1A5 4936
SLC14A2 4924
SLC44A5 4884
PCSK6 4846
SLC5A11 4845
TFRC 4842
PSMC1 4827
SLC16A8 4815
TRPV2 4685
SLC6A9 4651
ATP10D 4643
CP 4630
SLC27A4 4594
IREB2 4593
PSMC2 4543
SLC25A29 4527
SLC39A3 4518
GNG3 4481
ATP1A1 4348
MAGT1 4339
GNG8 4328
SLC17A5 4301
PSMD3 4297
PSMF1 4259
SLC24A2 4181
SGK2 4125
SLC2A6 4108
ATP2A1 3981
CYBRD1 3839
ATP6V1F 3811
PSMD13 3766
MMGT1 3748
SLC40A1 3693
ADD3 3689
ATP2A3 3651
CETP 3531
LCAT 3522
RSC1A1 3477
SEM1 3454
AVPR2 3452
ANO6 3404
NPC2 3326
SLC35B3 3293
RYR2 3281
CLIC2 3134
GNG2 3124
ANO5 3113
PSMA1 3111
CLCN7 3108
CFTR 3091
SLC30A2 3054
CLCN4 2925
BEST2 2915
AP2B1 2910
SLC2A12 2774
LRRC8A 2730
SLC39A4 2695
SLC46A1 2674
ANO2 2664
ATP13A1 2591
CAMK2G 2528
EIF2S3 2500
SLC2A13 2497
GNG4 2481
SLC5A12 2461
ADCY2 2455
APOE 2448
SMDT1 2357
LCN2 2300
CLCN2 2287
WNK2 2253
RYR1 2208
NIPAL2 2158
PSMD7 2084
SLC34A1 2067
SLC35A1 2052
TRPC6 1988
SLC38A2 1958
LIPG 1923
ABCC6 1908
LETM1 1870
HFE 1854
PSME4 1818
ABCD3 1785
PSMB2 1760
LRRC8D 1757
SLC22A18 1689
ABCC4 1639
ABCC5 1588
GNGT2 1513
ABCG2 1372
SLC29A4 1329
ABCC2 1314
SLC36A2 1262
TF 1246
TTYH2 1209
UBB 1026
VDAC2 985
NR1H3 954
ERLEC1 946
PSMD14 941
PSMC3 916
RAB11FIP2 900
SLC34A2 793
TPCN1 727
CES3 722
ATP1B2 710
NPC1 700
LIPC 684
SLC13A4 673
SLC47A1 670
MICU2 645
PSMB4 642
PSMC4 605
EIF2S2 554
SLC50A1 429
ADCY6 363
SLC11A2 361
SLC6A12 334
SCARB1 284
SLC33A1 222
ABCG8 214
SLC26A2 199
LIPA 151
MBTPS2 112
DERL2 50
CA2 42
FLVCR1 6
SLC2A9 -33
SLC22A16 -141
ABCB8 -239
SGK3 -258
SLC30A7 -342
SLC47A2 -362
SLC1A6 -412
PSMB8 -438
SLC1A4 -677
SLC24A3 -806
ATP8B1 -849
AHCYL2 -1050
SLC30A6 -1086
SLC7A9 -1094
TRPM3 -1180
VDAC1 -1213
VDAC3 -1232
CALM1 -1245
ADCY5 -1417
PRKAR2B -1442
ABCB4 -1460
SLC16A1 -1491
MFSD4B -1504
TRPV3 -1531
NIPAL1 -1587
EIF2S1 -1649
SLC39A5 -1711
SLC18A2 -1795
ASIC1 -1885
MCOLN2 -1950
SLC7A11 -1956
A2M -2133
SLC12A1 -2224
SLC26A1 -2279
ATP1A3 -2333
SLC20A1 -2366
NIPA1 -2394
ABCA2 -2422
SLC9B1 -2438
LCN12 -2483
PSMD10 -2515
SLC9A7 -2583
SLC28A2 -2588
ATP1A4 -2744
PSMA4 -2764
PSMA2 -2823
ADCY9 -2860
ABCB6 -2880
SLC13A3 -2906
ATP6V1C2 -2926
WNK3 -2932
SLC43A1 -2970
SLC12A3 -3030
SOAT2 -3064
DERL3 -3070
ARL2 -3181
SLC12A7 -3206
LMF2 -3268
SLC38A5 -3381
ATP10B -3457
UBA52 -3490
PSMB1 -3610
SLC3A1 -3624
RNF5 -3693
SLC14A1 -3878
ATP6V1E2 -3894
GNG11 -3895
LCN15 -3974
SLC9A5 -3987
TFR2 -3995
PSMB10 -4050
SLC13A5 -4094
PHB2 -4098
SLC25A5 -4227
SLC2A11 -4292
TRPM7 -4393
SLC5A2 -4481
PSMC5 -4553
SLC8A3 -4584
ZDHHC8 -4717
SLC34A3 -4730
FXYD1 -4745
SLC2A1 -4771
ATP6V1G1 -4775
GNB5 -4864
MYLIP -4888
TRPC3 -5092
SLC7A8 -5233
SLC20A2 -5242
SLC35D1 -5316
SLC4A4 -5354
SPG7 -5369
MYO5B -5379
SLC2A10 -5401
SLC7A1 -5419
SLC39A10 -5467
MCOLN3 -5479
SLC25A22 -5521
ABCA3 -5569
SLC25A6 -5588
SLC39A14 -5646
SLC5A6 -5755
LRRC8B -5762
SLC35B2 -5846
AQP11 -5860
FXYD2 -5861
GNG7 -5880
SLC18A1 -5899
ABCF1 -5990
PMPCA -6073
MRS2 -6099
ATP1B1 -6117
GNB3 -6125
ADD2 -6128
SCNN1D -6161
SLC2A8 -6202
SLC35A3 -6209
ATP10A -6221
SGK1 -6264
SKP1 -6297
ATP2B1 -6310
RYR3 -6315
PHB -6317
PSMA3 -6433
TRPV1 -6454
STOML2 -6475
DERL1 -6490
ATP13A4 -6538
ATP6V0A2 -6587
KCNJ11 -6641
BEST4 -6757
GLRX3 -6766
SLC41A2 -6797
SLC24A1 -6865
SLC30A5 -6922
SLC39A6 -7002
CAND1 -7058
SLC4A5 -7123
PSME2 -7327
CYB5RL -7366
SLC45A3 -7384
LMF1 -7415
ABCB9 -7468
PSMA5 -7476
TRPV6 -7513
ABCA5 -7521
ACO1 -7597
ABCA10 -7665
LRRC8C -7729
PSME1 -7778
ATP8A2 -7802
SLC4A7 -7812
SLC41A1 -7815
SLC25A10 -7923
ABCB7 -7951
PMPCB -8035
ASIC3 -8040
SLC7A6 -8043
AMN -8074
ABCG1 -8093
SLC26A11 -8096
SLC25A4 -8187
CUBN -8222
SLC5A3 -8234
ANO7 -8269
SLC4A3 -8361
SLC29A2 -8458
PSMB9 -8503
TRPC1 -8607
ARL2BP -8731
SLC9B2 -8740
SLC5A5 -8748
HMOX2 -8794
SLC38A1 -8808
SLC9A3 -8875
SLC22A17 -8876
MCUB -8878
ABCB1 -8886
ATP6V1G2 -9143
ATP8A1 -9218
SLC12A2 -9240
MICU3 -9246
SLC25A26 -9364
FXYD7 -9390
CUL1 -9420
ATP6V0E2 -9456
ANKH -9498
ABCD2 -9552
PEX3 -9554
ANO9 -9590
RPS27A -9723
NIPAL3 -9810
AFG3L2 -9813
PRKACB -9863
AKAP1 -9870
SLC4A10 -9890
CAMK2D -9907
SLC16A10 -9972
SLC5A10 -9980
WWP1 -9985
LSR -9987
LDLRAP1 -10002
ATP8B2 -10004
AQP3 -10148


Processing of Capped Intron-Containing Pre-mRNA

Processing of Capped Intron-Containing Pre-mRNA
852
set Processing of Capped Intron-Containing Pre-mRNA
setSize 238
pANOVA 1.29e-07
s.dist -0.199
p.adjustANOVA 2.51e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
NDC1 -10077
RBMX -9832
THOC3 -9772
NUP35 -9726
GCFC2 -9707
NUP88 -9668
NCBP2 -9631
SEH1L -9574
SRSF5 -9275
LSM5 -9206
HSPA8 -9129
PPIH -9028
SRSF11 -9002
SRSF10 -8821
SNRNP40 -8734
NXT1 -8699
HNRNPA3 -8697
SNRPF -8687
SRSF6 -8576
SNRPE -8564

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NDC1 -10077
RBMX -9832
THOC3 -9772
NUP35 -9726
GCFC2 -9707
NUP88 -9668
NCBP2 -9631
SEH1L -9574
SRSF5 -9275
LSM5 -9206
HSPA8 -9129
PPIH -9028
SRSF11 -9002
SRSF10 -8821
SNRNP40 -8734
NXT1 -8699
HNRNPA3 -8697
SNRPF -8687
SRSF6 -8576
SNRPE -8564
SF3A3 -8563
SNRPN -8556
SF3B3 -8519
SNU13 -8495
HNRNPA0 -8474
HNRNPR -8443
NUP43 -8368
NUP160 -8357
NUP107 -8285
RBM17 -8218
HNRNPA1 -8155
WBP11 -8149
PRPF19 -8121
RNPS1 -8030
LSM7 -7987
NUP188 -7953
THOC1 -7949
LSM4 -7839
NUDT21 -7791
SNRNP70 -7713
SNRPD2 -7545
NUP205 -7516
LSM8 -7483
PPWD1 -7374
PPIL1 -7334
HNRNPH1 -7320
SF3B1 -7276
CSTF1 -7266
SNRPA1 -7256
SRSF7 -7229
PLRG1 -7159
NUP54 -7131
NUP155 -7061
POLR2D -6856
MAGOHB -6726
SNRPD1 -6705
FYTTD1 -6647
DDX5 -6600
NUP93 -6458
SNRPD3 -6352
PPIE -6341
PRPF6 -6242
POLR2H -6200
SRSF2 -6188
METTL3 -6122
BCAS2 -5975
UPF3B -5843
PDCD7 -5777
SF3A2 -5775
SRRT -5701
SRSF3 -5550
PPIL3 -5431
NUP133 -5346
SNRNP200 -4953
POLR2K -4907
DHX15 -4896
PRPF31 -4832
PQBP1 -4696
MAGOH -4678
U2SURP -4521
SNRNP48 -4519
MTREX -4495
SNRPB -4187
NUP42 -4045
CPSF4 -4025
RNPC3 -4007
NUP210 -3949
POLR2I -3929
FUS -3863
PRPF8 -3849
TRA2B -3839
PRPF3 -3837
HNRNPD -3823
DHX9 -3778
DDX39A -3754
TPR -3744
CCAR1 -3543
LSM3 -3478
CWC22 -3466
NUP85 -3427
POLR2B -3384
SNRPB2 -3333
AAAS -3332
ELAVL1 -3119
SNRPC -3044
PTBP1 -2842
SLBP -2817
THOC2 -2624
PPIL4 -2614
THOC6 -2527
ZCRB1 -2492
NUP62 -2410
DNAJC8 -2315
METTL14 -2300
NUP37 -2275
ZRSR2 -2212
ALYREF -2176
SRRM1 -2172
U2AF1L4 -2154
CWC15 -2120
ZC3H11A -2004
SNRNP25 -1995
CHERP -1876
FIP1L1 -1860
PABPN1 -1789
PUF60 -1760
POM121C -1710
PHF5A -1599
SRSF1 -1573
RBM8A -1499
RANBP2 -1141
SF3B5 -997
DDX39B -960
NCBP1 -942
CSTF2T -904
CSTF2 -856
SARNP -641
CPSF1 -561
POLR2C -494
WDR33 -474
PRPF38A -184
POM121 -142
SNRPA -44
LSM2 -5
SF3A1 86
CWC27 110
PCBP2 240
NUP153 254
DDX46 256
PRPF40A 336
THOC7 348
SLU7 354
XAB2 437
U2AF2 483
SNRPG 560
RBM5 643
SF1 726
ISY1 828
SRRM2 1039
SYF2 1107
SYMPK 1165
CHTOP 1241
HNRNPF 1319
HNRNPU 1501
EIF4A3 1507
CRNKL1 1611
EIF4E 1661
DDX42 1823
POLR2L 2016
SNRNP27 2142
DHX16 2202
YBX1 2418
WTAP 2606
NUP50 2638
SMNDC1 2779
AQR 2936
HNRNPA2B1 3074
RBM22 3157
PCF11 3209
SNW1 3347
SF3B2 3446
SF3B6 3448
HNRNPUL1 3467
SF3B4 3527
CSTF3 3626
WBP4 3912
CTNNBL1 3970
POLR2G 4175
USP39 4209
POLR2F 4256
HNRNPC 4266
CDC5L 4279
LSM6 4446
HNRNPM 4537
TFIP11 4590
PRPF4 4659
DHX38 4887
DDX23 4899
RAE1 5007
CDC40 5078
CWC25 5092
POLR2E 5109
HNRNPL 5152
PRCC 5229
PAPOLA 5344
PPIL6 5450
HNRNPK 5529
CLP1 5591
POLR2J 5598
TXNL4A 5755
NXF1 5811
BUD31 5855
NUP98 5874
SNRNP35 5878
CPSF7 5894
GPKOW 6169
GTF2F2 6257
U2AF1 6360
SART1 6691
GTF2F1 6738
SRSF4 7085
CPSF2 7191
CPSF3 7310
SUGP1 7370
SEC13 7506
PCBP1 7665
POLR2A 7852
CD2BP2 8001
HNRNPH2 8018
EFTUD2 8455
ZMAT5 8694
SRSF9 8713
GLE1 9246
NUP58 9577
CASC3 9610
NUP214 10131
POLDIP3 10182
THOC5 10316


Regulation of lipid metabolism by PPARalpha

Regulation of lipid metabolism by PPARalpha
984
set Regulation of lipid metabolism by PPARalpha
setSize 106
pANOVA 1.33e-07
s.dist 0.296
p.adjustANOVA 2.56e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
PPARG 11451
NCOR2 11217
ACSL1 11102
CD36 10947
CPT2 10925
FADS1 10870
RGL1 10752
MTF1 10630
ME1 10563
NFYC 10461
NCOA6 10326
CARM1 10313
ACOX1 10277
ARNT 10231
RXRA 10073
TXNRD1 9890
SREBF2 9844
PLIN2 9820
EP300 9789
CDK19 9729

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PPARG 11451
NCOR2 11217
ACSL1 11102
CD36 10947
CPT2 10925
FADS1 10870
RGL1 10752
MTF1 10630
ME1 10563
NFYC 10461
NCOA6 10326
CARM1 10313
ACOX1 10277
ARNT 10231
RXRA 10073
TXNRD1 9890
SREBF2 9844
PLIN2 9820
EP300 9789
CDK19 9729
SP1 9699
APOA2 9687
NR1H2 9521
MED13L 9444
FDFT1 9429
FAM120B 9384
ESRRA 9192
HMGCR 9117
MED20 8757
MED8 8643
MED18 8563
ALAS1 8407
NCOA3 8176
NCOR1 8153
CREBBP 8143
MED25 8136
NCOA2 7898
TBL1X 7764
MED12 7718
SMARCD3 7698
FHL2 7159
ARNTL 6905
NCOA1 6885
HELZ2 6747
NFYA 6667
ANGPTL4 6584
MED26 6537
ABCA1 6506
SLC27A1 5937
MED14 5610
HDAC3 5437
CPT1A 5231
PPARA 4862
TBL1XR1 4852
GLIPR1 4675
THRAP3 4646
CDK8 4340
MED16 4162
TIAM2 3254
MED11 3182
RXRB 2848
MED22 2682
GPS2 2541
TRIB3 2492
SREBF1 2292
SIN3B 2071
MED23 1915
HMGCS1 1443
MED24 1185
MED7 1178
AHR 1155
NR1H3 954
MED13 630
PEX11A 600
MED28 479
CHD9 97
G0S2 17
PPARGC1B -31
NRF1 -105
MED15 -911
MED1 -971
TNFRSF21 -1215
AHRR -1354
ABCB4 -1460
MED9 -1496
PPARGC1A -1762
MED19 -1831
GRHL1 -1905
NPAS2 -1986
MED4 -2264
MED31 -2514
MED17 -2648
MED30 -2845
MED27 -2978
MED21 -3045
MED29 -3703
TGS1 -4316
CLOCK -5087
MED6 -6714
CCNC -6937
ACADM -7323
SIN3A -7740
MED10 -8535
RORA -9193
NR1D1 -9199
NFYB -10059


Intra-Golgi and retrograde Golgi-to-ER traffic

Intra-Golgi and retrograde Golgi-to-ER traffic
569
set Intra-Golgi and retrograde Golgi-to-ER traffic
setSize 179
pANOVA 1.62e-07
s.dist 0.227
p.adjustANOVA 3.06e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
PLIN3 11351
CUX1 11300
COPG1 11142
GALNT2 10885
MAN1A1 10830
DCTN4 10682
ARF1 10610
COPA 10521
IGF2R 10494
KIF1B 10454
CYTH4 10450
DCTN2 10412
ACTR1A 10310
TGOLN2 10307
MAN2A2 10274
RAB39A 10255
STX10 10228
RAB1B 10055
COG7 9987
RAB1A 9971

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PLIN3 11351
CUX1 11300
COPG1 11142
GALNT2 10885
MAN1A1 10830
DCTN4 10682
ARF1 10610
COPA 10521
IGF2R 10494
KIF1B 10454
CYTH4 10450
DCTN2 10412
ACTR1A 10310
TGOLN2 10307
MAN2A2 10274
RAB39A 10255
STX10 10228
RAB1B 10055
COG7 9987
RAB1A 9971
RAB6A 9958
NSF 9870
PLA2G4A 9803
BICD2 9707
KDELR1 9613
CAPZB 9575
DCTN1 9558
CAPZA1 9530
KIF1C 9483
ARF3 9465
KIF3C 9374
ARF4 9348
VAMP3 9311
VTI1A 9303
SNAP29 9157
GOLIM4 9092
GOLGA1 9075
COPB2 8898
KLC1 8888
COPG2 8709
STX5 8547
KIF13B 8431
NAA38 8425
COG4 8402
RAB36 8383
ARF5 8313
SURF4 8306
DYNC1LI1 8276
COPE 8230
CAPZA2 8225
KIF5B 8197
TMED9 8028
COPB1 7997
AGPAT3 7932
PAFAH1B1 7857
STX6 7734
GBF1 7683
RIC1 7660
DYNC1LI2 7644
YKT6 7621
DCTN6 7540
GOLGA5 7519
NAPG 7516
ARFGAP3 7424
RGP1 7355
RAB18 7038
ARCN1 6965
RAB43 6846
KIF9 6805
DYNC1I2 6705
NAPA 6660
DCTN3 6625
RAB3GAP2 6599
GALNT1 6495
KLC3 6451
RABEPK 6419
STX18 6405
KDELR2 6387
VPS53 6373
SEC22B 6272
PAFAH1B2 5996
GOSR2 5986
CENPE 5930
RACGAP1 5897
ACTR10 5886
KIF18B 5806
KIF3B 5396
TMED2 5345
RAB3GAP1 5167
KIF27 5112
RAB33B 5028
STX16 4979
KIF21B 4976
VPS54 4853
KIF4A 4526
ARFGAP2 4331
KIF23 4278
TMED7 3978
GCC1 3975
KIF20A 3824
TMED3 3420
VPS52 3262
NAPB 3180
CYTH2 3016
ARFGAP1 2978
DYNC1I1 2879
COG5 2352
KIF6 2255
KIF2C 2011
DYNC1H1 1705
DYNLL1 1530
RAB41 1488
TMF1 1460
NBAS 1441
KIF19 1011
KDELR3 869
VAMP4 607
KIF11 545
COPZ1 412
COG8 406
USP6NL 325
DCTN5 297
KIFC1 288
VPS45 -382
KIF18A -394
KIF26A -414
ZW10 -627
KIF15 -1564
BET1L -1574
RAB9A -1713
RAB6B -1849
SYS1 -2040
COG3 -2175
BICD1 -2303
TRIP11 -2705
ARL1 -2770
GOSR1 -3080
KIFC2 -3136
GOLGA4 -3561
RHOBTB3 -3616
KIFAP3 -3831
MAN2A1 -4015
ARFIP2 -4029
PAFAH1B3 -4044
MAN1A2 -4146
RAB9B -4177
KLC4 -4248
CYTH3 -4278
KIF28P -4361
TMED10 -4413
ARFRP1 -4525
KIF16B -4619
M6PR -4860
DYNLL2 -4904
USE1 -5115
KLC2 -5453
COG2 -5554
COPZ2 -5974
BNIP1 -6184
GCC2 -6501
COG6 -6645
NAA35 -6750
KIF21A -6834
KIF2A -6844
KIF5A -6961
COG1 -7045
PLA2G6 -7168
KIF20B -7260
KIF26B -7360
NAA30 -7523
VPS51 -8242
RAB30 -8666
RINT1 -8985
CYTH1 -9019
SCOC -9113
KIF3A -9438
KIF22 -9850
MAN1C1 -9944
KIF5C -10128


Activation of ATR in response to replication stress

Activation of ATR in response to replication stress
33
set Activation of ATR in response to replication stress
setSize 37
pANOVA 2.01e-07
s.dist -0.494
p.adjustANOVA 3.75e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
MCM3 -9943
RAD1 -9896
RPA1 -9799
RFC3 -9405
MCM7 -9325
RPA3 -9220
DBF4 -8907
RFC4 -8897
MCM6 -8631
ORC5 -8539
RAD17 -8493
ORC2 -8256
ORC3 -7889
RFC5 -7574
RAD9A -7462
MCM4 -7086
MCM2 -6880
ORC4 -6267
CHEK1 -6143
MCM8 -5713

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MCM3 -9943
RAD1 -9896
RPA1 -9799
RFC3 -9405
MCM7 -9325
RPA3 -9220
DBF4 -8907
RFC4 -8897
MCM6 -8631
ORC5 -8539
RAD17 -8493
ORC2 -8256
ORC3 -7889
RFC5 -7574
RAD9A -7462
MCM4 -7086
MCM2 -6880
ORC4 -6267
CHEK1 -6143
MCM8 -5713
ATR -5340
CDC45 -5132
RPA2 -4811
MCM10 -4587
CDC7 -4493
CDK2 -3614
ATRIP -3603
ORC1 -2973
MCM5 -2327
CDC6 -1597
CDC25A 317
CLSPN 1968
HUS1 4236
ORC6 5337
RFC2 5478
CDC25C 5800
RAD9B 6597


PD-1 signaling

PD-1 signaling
777
set PD-1 signaling
setSize 28
pANOVA 2.24e-07
s.dist -0.565
p.adjustANOVA 4.12e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
TRBV12-3 -9971
TRAC -9703
HLA-DQB2 -9656
LCK -9556
TRBC1 -9303
TRAV29DV5 -9278
CD3E -9249
TRAV19 -9248
HLA-DRA -9006
HLA-DQA2 -8774
CD247 -8741
HLA-DPB1 -8397
TRBV7-9 -8303
CD3D -8297
HLA-DPA1 -8217
CD3G -8111
CD274 -7895
CD4 -6881
HLA-DQA1 -6389
PDCD1 -5516

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TRBV12-3 -9971
TRAC -9703
HLA-DQB2 -9656
LCK -9556
TRBC1 -9303
TRAV29DV5 -9278
CD3E -9249
TRAV19 -9248
HLA-DRA -9006
HLA-DQA2 -8774
CD247 -8741
HLA-DPB1 -8397
TRBV7-9 -8303
CD3D -8297
HLA-DPA1 -8217
CD3G -8111
CD274 -7895
CD4 -6881
HLA-DQA1 -6389
PDCD1 -5516
TRAV8-4 -4769
HLA-DQB1 -4459
HLA-DRB1 -334
PDCD1LG2 273
HLA-DRB5 748
PTPN11 6524
CSK 9400
PTPN6 10446


Golgi-to-ER retrograde transport

Golgi-to-ER retrograde transport
467
set Golgi-to-ER retrograde transport
setSize 111
pANOVA 2.5e-07
s.dist 0.283
p.adjustANOVA 4.54e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
COPG1 11142
GALNT2 10885
DCTN4 10682
ARF1 10610
COPA 10521
KIF1B 10454
DCTN2 10412
ACTR1A 10310
RAB1B 10055
RAB1A 9971
RAB6A 9958
NSF 9870
PLA2G4A 9803
BICD2 9707
KDELR1 9613
CAPZB 9575
DCTN1 9558
CAPZA1 9530
KIF1C 9483
ARF3 9465

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
COPG1 11142
GALNT2 10885
DCTN4 10682
ARF1 10610
COPA 10521
KIF1B 10454
DCTN2 10412
ACTR1A 10310
RAB1B 10055
RAB1A 9971
RAB6A 9958
NSF 9870
PLA2G4A 9803
BICD2 9707
KDELR1 9613
CAPZB 9575
DCTN1 9558
CAPZA1 9530
KIF1C 9483
ARF3 9465
KIF3C 9374
ARF4 9348
COPB2 8898
KLC1 8888
COPG2 8709
KIF13B 8431
ARF5 8313
SURF4 8306
DYNC1LI1 8276
COPE 8230
CAPZA2 8225
KIF5B 8197
TMED9 8028
COPB1 7997
AGPAT3 7932
PAFAH1B1 7857
GBF1 7683
DYNC1LI2 7644
DCTN6 7540
NAPG 7516
ARFGAP3 7424
RAB18 7038
ARCN1 6965
KIF9 6805
DYNC1I2 6705
NAPA 6660
DCTN3 6625
RAB3GAP2 6599
GALNT1 6495
KLC3 6451
STX18 6405
KDELR2 6387
SEC22B 6272
PAFAH1B2 5996
CENPE 5930
RACGAP1 5897
ACTR10 5886
KIF18B 5806
KIF3B 5396
TMED2 5345
RAB3GAP1 5167
KIF27 5112
KIF21B 4976
KIF4A 4526
ARFGAP2 4331
KIF23 4278
TMED7 3978
KIF20A 3824
TMED3 3420
NAPB 3180
ARFGAP1 2978
DYNC1I1 2879
KIF6 2255
KIF2C 2011
DYNC1H1 1705
DYNLL1 1530
NBAS 1441
KIF19 1011
KDELR3 869
KIF11 545
COPZ1 412
DCTN5 297
KIFC1 288
KIF18A -394
KIF26A -414
ZW10 -627
KIF15 -1564
RAB6B -1849
BICD1 -2303
KIFC2 -3136
KIFAP3 -3831
PAFAH1B3 -4044
KLC4 -4248
KIF28P -4361
TMED10 -4413
KIF16B -4619
DYNLL2 -4904
USE1 -5115
KLC2 -5453
COPZ2 -5974
BNIP1 -6184
KIF21A -6834
KIF2A -6844
KIF5A -6961
PLA2G6 -7168
KIF20B -7260
KIF26B -7360
RINT1 -8985
KIF3A -9438
KIF22 -9850
KIF5C -10128


Toll Like Receptor 4 (TLR4) Cascade

Toll Like Receptor 4 (TLR4) Cascade
1237
set Toll Like Receptor 4 (TLR4) Cascade
setSize 121
pANOVA 2.61e-07
s.dist 0.271
p.adjustANOVA 4.67e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
MYD88 11331
MAP3K8 11291
ITGAM 11269
MAPKAPK3 11249
S100A12 11206
MAPK1 11193
MAPK14 11115
RPS6KA1 11103
NKIRAS2 11077
RIPK3 11013
MAP2K6 10958
CD36 10947
IRAK3 10909
ITGB2 10861
BTK 10849
TLR2 10535
MAP2K3 10377
DNM2 10373
PLCG2 10244
MAP2K1 10148

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MYD88 11331
MAP3K8 11291
ITGAM 11269
MAPKAPK3 11249
S100A12 11206
MAPK1 11193
MAPK14 11115
RPS6KA1 11103
NKIRAS2 11077
RIPK3 11013
MAP2K6 10958
CD36 10947
IRAK3 10909
ITGB2 10861
BTK 10849
TLR2 10535
MAP2K3 10377
DNM2 10373
PLCG2 10244
MAP2K1 10148
TLR1 10059
MAPK7 10035
NOD2 9983
MEF2A 9891
MAPK3 9750
TLR4 9549
CD14 9466
IKBKG 9441
LY96 9322
UBE2D1 9286
PELI3 9118
TLR6 9070
TICAM1 8878
TIRAP 8858
MAPKAPK2 8852
MAPK10 8849
FADD 8785
CHUK 8723
UBE2D3 8641
TANK 8576
DUSP3 8510
IKBKE 8263
IRAK1 7970
TNIP2 7810
MAP2K4 7754
PPP2CB 7451
VRK3 7206
NFKBIB 6845
PPP2CA 6806
TAB3 6655
PPP2R5D 6601
PTPN11 6524
MAP3K1 6286
APP 6245
PELI2 6164
UBC 6135
DNM1 5998
FBXW11 5621
NFKBIA 5457
PPP2R1A 5189
AGER 4895
TBK1 4856
PELI1 4802
SOCS1 4688
TRAF6 4673
RPS6KA2 4384
TICAM2 4262
IRF7 4132
MAP3K7 4043
DNM3 3523
RIPK1 3206
JUN 3122
NFKB1 2860
FOS 2787
BIRC2 2697
ATF1 2556
ECSIT 2321
TAB2 1975
IKBKB 1759
TAB1 1754
MAP2K7 1550
LY86 1163
UBB 1026
RPS6KA3 649
PPP2R1B 89
RELA -204
ATF2 -657
UBE2D2 -801
UBE2V1 -1252
S100B -1351
UBE2N -2071
DUSP4 -2116
RIPK2 -2451
DUSP7 -2452
IRAK2 -2799
DUSP6 -3055
UBA52 -3490
NFKB2 -3527
NOD1 -3652
CREB1 -3977
BTRC -4212
MAPK11 -4641
CASP8 -4824
BPI -5410
MAPK9 -5454
ELK1 -5884
CD180 -6005
MEF2C -6025
NKIRAS1 -6234
SKP1 -6297
HMGB1 -6699
IRF3 -6721
SIGIRR -6838
TRAF3 -7539
SARM1 -8283
PTPN4 -8389
MAPK8 -8929
RPS6KA5 -9386
CUL1 -9420
RPS27A -9723
BIRC3 -10039


Generation of second messenger molecules

Generation of second messenger molecules
443
set Generation of second messenger molecules
setSize 38
pANOVA 2.64e-07
s.dist -0.482
p.adjustANOVA 4.67e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
TRBV12-3 -9971
TRAC -9703
ITK -9674
HLA-DQB2 -9656
EVL -9560
LCK -9556
LAT -9470
PLCG1 -9412
TRBC1 -9303
TRAV29DV5 -9278
CD3E -9249
TRAV19 -9248
HLA-DRA -9006
NCK1 -8975
HLA-DQA2 -8774
ZAP70 -8755
CD247 -8741
HLA-DPB1 -8397
TRBV7-9 -8303
CD3D -8297

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TRBV12-3 -9971
TRAC -9703
ITK -9674
HLA-DQB2 -9656
EVL -9560
LCK -9556
LAT -9470
PLCG1 -9412
TRBC1 -9303
TRAV29DV5 -9278
CD3E -9249
TRAV19 -9248
HLA-DRA -9006
NCK1 -8975
HLA-DQA2 -8774
ZAP70 -8755
CD247 -8741
HLA-DPB1 -8397
TRBV7-9 -8303
CD3D -8297
HLA-DPA1 -8217
CD3G -8111
CD4 -6881
HLA-DQA1 -6389
PAK3 -5908
TRAV8-4 -4769
HLA-DQB1 -4459
GRAP2 -2088
CD101 -1089
HLA-DRB1 -334
HLA-DRB5 748
ENAH 3578
LCP2 3759
PAK2 9042
PAK1 10043
PLCG2 10244
VASP 10286
WAS 10777


Response to elevated platelet cytosolic Ca2+

Response to elevated platelet cytosolic Ca2+
1008
set Response to elevated platelet cytosolic Ca2+
setSize 110
pANOVA 2.85e-07
s.dist 0.283
p.adjustANOVA 4.96e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
F5 11434
SERPINA1 11407
QSOX1 11369
CD63 11355
STXBP2 11285
TIMP1 11275
GTPBP2 11180
CYB5R1 11052
TOR4A 11002
FERMT3 10998
CD36 10947
APLP2 10928
ALDOA 10868
CLU 10812
HGF 10417
PECAM1 10414
SCCPDH 10298
ACTN4 10230
TLN1 10191
LHFPL2 9956

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
F5 11434
SERPINA1 11407
QSOX1 11369
CD63 11355
STXBP2 11285
TIMP1 11275
GTPBP2 11180
CYB5R1 11052
TOR4A 11002
FERMT3 10998
CD36 10947
APLP2 10928
ALDOA 10868
CLU 10812
HGF 10417
PECAM1 10414
SCCPDH 10298
ACTN4 10230
TLN1 10191
LHFPL2 9956
CAP1 9934
GAS6 9901
SRGN 9887
WDR1 9868
ACTN1 9811
CFL1 9794
ANXA5 9269
CALU 9049
LAMP2 9034
VTI1B 8933
PSAP 8894
ALB 8630
PRKCB 8577
PFN1 8397
FLNA 8318
TUBA4A 8035
F8 8026
SYTL4 7697
CLEC3B 7525
ITGA2B 7387
STXBP3 7210
HSPA5 7027
STX4 7026
APP 6245
VCL 6193
CD109 6110
ECM1 6098
TTN 6088
TGFB2 6083
CD9 5818
VEGFA 5648
VEGFC 5567
TGFB1 5504
SELP 5380
PDGFA 5341
EGF 5267
SERPINE1 5005
PLEK 4699
THBS1 4645
PROS1 4191
VWF 3870
PHACTR2 3743
MMRN1 3618
TIMP3 3154
ITGB3 2944
LY6G6F 2813
TAGLN2 2525
ORM1 2075
MAGED2 1652
ABCC4 1639
F13A1 1493
BRPF3 1249
TF 1246
CHID1 786
RAB27B 774
ORM2 565
CFD 461
MANF 445
PLG 218
PCYOX1L -458
TMSB4X -850
APOOL -867
SPARC -1002
CALM1 -1245
SERPINF2 -1375
ENDOD1 -1464
A1BG -1468
FN1 -1829
PPBP -1960
PF4 -2122
A2M -2133
PRKCA -2408
CTSW -2441
ITIH4 -2921
TMX3 -3613
TEX264 -4024
NHLRC2 -4700
OLA1 -5737
PPIA -6498
SELENOP -6746
TGFB3 -6903
ITIH3 -7066
CDC37L1 -7116
LGALS3BP -7405
SOD1 -7420
SERPING1 -7610
FAM3C -9260
VEGFB -9481
PDGFB -9562
HABP4 -10030


RAB GEFs exchange GTP for GDP on RABs

RAB GEFs exchange GTP for GDP on RABs
876
set RAB GEFs exchange GTP for GDP on RABs
setSize 88
pANOVA 3.07e-07
s.dist 0.316
p.adjustANOVA 5.28e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
RIN1 11169
ULK1 11151
SBF2 11135
DENND3 11024
RAB10 10956
RIN2 10772
RAB31 10661
RAB32 10626
RAB13 10611
MON1B 10423
RAB39A 10255
RAB7A 10115
RAB1B 10055
RAB1A 9971
RAB6A 9958
RAB5C 9864
DENND5A 9804
TRAPPC12 9770
RAB27A 9628
TRAPPC1 9087

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RIN1 11169
ULK1 11151
SBF2 11135
DENND3 11024
RAB10 10956
RIN2 10772
RAB31 10661
RAB32 10626
RAB13 10611
MON1B 10423
RAB39A 10255
RAB7A 10115
RAB1B 10055
RAB1A 9971
RAB6A 9958
RAB5C 9864
DENND5A 9804
TRAPPC12 9770
RAB27A 9628
TRAPPC1 9087
YWHAE 8971
DENND4B 8934
RAB3IL1 8870
HPS1 8846
GAPVD1 8844
RAB5B 8258
RABGEF1 8058
GDI1 7789
RAB8B 7739
TRAPPC8 7708
RIC1 7660
DENND2C 7658
RAB35 7522
TRAPPC11 7513
ALS2 7445
RGP1 7355
DENND1A 7260
RAB5A 7154
RAB18 7038
GDI2 6949
RAB3GAP2 6599
TRAPPC9 6548
AKT1 6498
RAB3A 6284
ANKRD27 6228
RAB21 6196
RAB7B 6060
CCZ1 5832
RAB8A 5522
AKT2 5502
RAB14 5469
CCZ1B 5430
RAB3GAP1 5167
TRAPPC3 4443
TRAPPC5 3257
MADD 3143
TRAPPC10 2565
DENND1C 2358
DENND6A 1376
TRAPPC6B 1327
CHM 1115
RAB27B 774
MON1A 707
DENND6B 706
TRAPPC13 -481
RAB3IP -569
RINL -1455
RAB9A -1713
RAB6B -1849
TRAPPC2L -1855
RAB12 -2139
TRAPPC4 -2490
DENND4A -2494
DENND1B -3163
SBF1 -3176
RAB38 -3316
DENND2A -3622
DENND4C -3756
RAB9B -4177
CHML -4951
DENND5B -6013
HPS4 -6635
TRAPPC2 -7043
RAB39B -8372
AKT3 -8810
DENND2D -9419
TRAPPC6A -9543
ALS2CL -10013


RHO GTPases activate PKNs

RHO GTPases activate PKNs
892
set RHO GTPases activate PKNs
setSize 48
pANOVA 3.53e-07
s.dist 0.425
p.adjustANOVA 6e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2AJ 11447.0
RAC1 10624.0
YWHAG 10453.0
MYL6 10185.0
YWHAH 10050.0
PAK1 10043.0
H2BC21 9690.0
RHOA 9401.0
H2BC12 9280.0
MYH9 9224.0
H3-3A 8985.0
YWHAE 8971.0
H3C15 8929.5
H2BC4 8925.0
H2AC20 8893.0
PDPK1 8710.0
MYH10 8632.0
PPP1R12B 8489.0
RHOB 7921.0
NCOA2 7898.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2AJ 11447.0
RAC1 10624.0
YWHAG 10453.0
MYL6 10185.0
YWHAH 10050.0
PAK1 10043.0
H2BC21 9690.0
RHOA 9401.0
H2BC12 9280.0
MYH9 9224.0
H3-3A 8985.0
YWHAE 8971.0
H3C15 8929.5
H2BC4 8925.0
H2AC20 8893.0
PDPK1 8710.0
MYH10 8632.0
PPP1R12B 8489.0
RHOB 7921.0
NCOA2 7898.0
PPP1R12A 7801.0
H2BC5 6759.0
PPP1CB 6745.0
AR 6643.0
PKN1 6333.0
H2BC17 6188.0
H2BC11 6121.0
CDC25C 5800.0
MYL12B 5703.0
H2AC6 5440.0
YWHAZ 5202.0
YWHAB 4721.0
RHOC 4639.0
KLK2 4578.0
H2AZ1 4378.0
PKN3 2892.0
H2BC15 2474.0
MYL9 1931.0
SFN 1840.0
PKN2 418.0
H2BU1 298.0
MYH11 -2243.0
KDM4C -3380.0
PPP1R14A -3415.0
YWHAQ -4624.0
H2AZ2 -5576.0
H2BC9 -5728.0
KDM1A -7314.0


Diseases of signal transduction by growth factor receptors and second messengers

Diseases of signal transduction by growth factor receptors and second messengers
296
set Diseases of signal transduction by growth factor receptors and second messengers
setSize 340
pANOVA 5.72e-07
s.dist 0.158
p.adjustANOVA 9.6e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
NCSTN 11452
FZD5 11440
CUX1 11300
NCOR2 11217
MAPK1 11193
CASP9 11186
KREMEN1 11087
ERLIN2 11011
TGFA 10983
ADAM17 10964
OS9 10951
HDAC4 10884
PIK3AP1 10882
LYN 10810
MARK3 10787
TCF7L2 10773
AGTRAP 10764
GRB2 10733
ARRB2 10688
CTBP2 10652

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NCSTN 11452
FZD5 11440
CUX1 11300
NCOR2 11217
MAPK1 11193
CASP9 11186
KREMEN1 11087
ERLIN2 11011
TGFA 10983
ADAM17 10964
OS9 10951
HDAC4 10884
PIK3AP1 10882
LYN 10810
MARK3 10787
TCF7L2 10773
AGTRAP 10764
GRB2 10733
ARRB2 10688
CTBP2 10652
MAML3 10651
RHOG 10635
RAC1 10624
APBB1IP 10622
KSR1 10576
GAB2 10528
SPRED2 10499
PSEN1 10429
HGF 10417
MAP3K11 10375
PAPSS1 10336
VAV1 10226
TLN1 10191
RBPJ 10176
MAP2K1 10148
PSMD4 10088
MAML1 10046
IQGAP1 10037
PDGFRA 10015
ADAM10 9992
GSK3A 9979
PPP2R5B 9913
CBL 9903
PPP2R5A 9827
FOXO3 9800
EP300 9789
MAPK3 9750
STAT3 9739
BIN2 9720
RAF1 9686
CTNNB1 9670
BAG4 9667
MRAS 9617
PTEN 9545
SHC1 9541
KL 9509
NOTCH1 9499
APH1B 9474
IRS2 9427
CSK 9400
NEURL1 9207
FOXO4 9205
BCL2L11 9144
PIK3CB 9126
PIK3CD 8956
FKBP1A 8827
LRRFIP1 8804
PSMD9 8766
STAT5B 8742
CHUK 8723
PSME3 8716
PDPK1 8710
GAB1 8670
QKI 8642
TRAK1 8484
PSMB7 8460
AKT1S1 8410
CSNK1A1 8266
PSMB5 8265
JAG1 8240
RAC2 8237
PSMD1 8184
NCOR1 8153
NF1 8146
CREBBP 8143
PSMD2 8139
PSMB3 8005
KDM7A 8000
ETV6 7963
SEL1L 7883
AP3B1 7854
POLR2A 7852
PSMA7 7840
STAT5A 7833
VCP 7804
PSMD11 7775
TBL1X 7764
PTPN12 7724
PSMD5 7646
HES1 7535
PPP2CB 7451
PSMB6 7399
HDAC7 7388
ITGA2B 7387
RAP1A 7335
PSMD6 7307
BAD 7263
MAP2K2 7222
GSK3B 7147
AGGF1 7121
PSENEN 7091
STRN 7079
RAP1B 6962
PSMD12 6820
PPP2CA 6806
PDGFRB 6793
PPP1CB 6745
GTF2F1 6738
MYO18A 6636
FGFR1 6607
PPP2R5D 6601
CLCN6 6549
PTPN11 6524
PIK3R2 6511
AKT1 6498
SMAD2 6291
GTF2F2 6257
HDAC8 6235
BRAP 6218
VCL 6193
UBC 6135
KRAS 6132
CDC37 6119
SHOC2 6108
ARAF 6089
ATG7 6082
MDM2 6043
FAM114A2 5914
ZMYM2 5875
TGFBR2 5802
SYVN1 5702
PSMD8 5687
POLR2J 5598
CDKN1A 5537
TGFB1 5504
AKT2 5502
HDAC11 5471
HDAC3 5437
PDGFA 5341
EGF 5267
PSMA6 5209
PPP2R1A 5189
POLR2E 5109
APC 5030
KREMEN2 4978
TGFBR1 4966
PSMC6 4959
NRAS 4907
TBL1XR1 4852
PSMC1 4827
YWHAB 4721
MAPKAP1 4588
PSMC2 4543
JAK2 4428
BRAF 4367
CDK8 4340
TSC2 4311
PSMD3 4297
PSMF1 4259
POLR2F 4256
POLR2G 4175
RBX1 3957
ARRB1 3956
VWF 3870
PSMD13 3766
FAM131B 3663
SPRED1 3532
TNKS2 3514
FZD4 3498
SEM1 3454
HDAC5 3369
SNW1 3347
FGFR1OP2 3239
PSMA1 3111
ITGB3 2944
CTBP1 2903
RPS6KB2 2842
PIK3R3 2676
APH1A 2563
CAMK2G 2528
HDAC10 2431
SND1 2415
AREG 2386
PIK3CA 2133
SPRED3 2117
PSMD7 2084
LMNA 2076
HBEGF 2064
KAT2B 2054
POLR2L 2016
PSME4 1818
MTOR 1777
PSMB2 1760
KIAA1549 1682
BCR 1529
UBB 1026
ERLEC1 946
PSMD14 941
PSMC3 916
HDAC1 650
PSMB4 642
PSMC4 605
ERBB3 599
PPP1CC 519
HDAC6 243
KSR2 229
TRIM24 173
PPP2R1B 89
ERBIN 87
DERL2 50
TNKS 15
EREG -249
PSMB8 -438
POLR2C -494
NCBP1 -942
DUSP10 -973
MLST8 -1064
FRS2 -1144
EPGN -1241
CALM1 -1245
FBXW7 -1315
CD86 -1606
CNTRL -1810
FN1 -1829
FIP1L1 -1860
FGF23 -1952
DUSP7 -2452
NEURL1B -2466
PSMD10 -2515
FXR1 -2566
PPP2R5E -2595
NR4A1 -2672
PSMA4 -2764
PSMA2 -2823
YES1 -2846
DUSP8 -2914
SOS1 -2983
AXIN1 -2986
ESR1 -3021
DUSP6 -3055
CDKN1B -3127
POLR2B -3384
UBA52 -3490
GOLGA4 -3561
PSMB1 -3610
SMAD4 -3639
NRG4 -3673
LRP5 -3864
FGF22 -3881
POLR2I -3929
CREB1 -3977
HSP90AA1 -4016
PSMB10 -4050
CNKSR2 -4467
FGFR4 -4539
PSMC5 -4553
CD19 -4586
MIB2 -4725
POLR2K -4907
AKAP9 -4929
MAMLD1 -4969
HHAT -5136
PPP2R5C -5198
FYN -5211
RICTOR -5264
MIB1 -5272
HRAS -5273
JAG2 -5287
FGFR1OP -5744
FGFR2 -5834
IRS1 -6033
PORCN -6126
ERBB2 -6142
FZD8 -6149
CPSF6 -6183
POLR2H -6200
FGF2 -6231
SKP1 -6297
PHB -6317
PSEN2 -6393
SRC -6396
PSMA3 -6433
PRR5 -6787
POLR2D -6856
HDAC2 -6871
CCNC -6937
MAML2 -7122
LRP6 -7232
NRG1 -7233
WDR48 -7288
PSME2 -7327
FGF7 -7330
PSMA5 -7476
ESR2 -7755
PSME1 -7778
SMAD3 -7868
ZC3HAV1 -8023
DLL1 -8167
DUSP16 -8213
CD80 -8215
CNKSR1 -8238
FZD6 -8438
FGF9 -8476
PSMB9 -8503
AMER1 -8632
AGK -8639
HDAC9 -8695
TENT4A -8759
AKT3 -8810
PIK3R1 -8831
KAT2A -9063
RNF43 -9119
MYC -9357
KANK1 -9399
PLCG1 -9412
CUL1 -9420
STAT1 -9448
LCK -9556
PDGFB -9562
NCBP2 -9631
MPRIP -9692
RPS27A -9723
FOXO1 -9731
ZFYVE9 -9740
PEBP1 -9843
CAMK2D -9907
ICOS -9952
TRAT1 -10049
KIT -10114
CD28 -10159


Signaling by NOTCH

Signaling by NOTCH
1106
set Signaling by NOTCH
setSize 182
pANOVA 6.06e-07
s.dist 0.214
p.adjustANOVA 1.01e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
NCSTN 11452
H2AJ 11447
NOTCH3 11420
NUMB 11392
TLE3 11222
NCOR2 11217
ADAM17 10964
FURIN 10905
HDAC4 10884
WWP2 10784
ARRB2 10688
PLXND1 10671
MAML3 10651
AGO4 10537
RUNX1 10531
PSEN1 10429
TLE4 10384
ATP2A2 10359
NOTCH4 10293
ST3GAL4 10218

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NCSTN 11452.0
H2AJ 11447.0
NOTCH3 11420.0
NUMB 11392.0
TLE3 11222.0
NCOR2 11217.0
ADAM17 10964.0
FURIN 10905.0
HDAC4 10884.0
WWP2 10784.0
ARRB2 10688.0
PLXND1 10671.0
MAML3 10651.0
AGO4 10537.0
RUNX1 10531.0
PSEN1 10429.0
TLE4 10384.0
ATP2A2 10359.0
NOTCH4 10293.0
ST3GAL4 10218.0
RBPJ 10176.0
PSMD4 10088.0
MAML1 10046.0
ADAM10 9992.0
RAB6A 9958.0
EP300 9789.0
H2BC21 9690.0
NOTCH1 9499.0
APH1B 9474.0
E2F3 9367.0
H2BC12 9280.0
NEURL1 9207.0
TACC3 9187.0
DTX4 9123.0
DTX2 9081.0
HIF1A 9002.0
H3-3A 8985.0
H3C15 8929.5
H2BC4 8925.0
H2AC20 8893.0
AGO1 8810.0
PSMD9 8766.0
PSME3 8716.0
TFDP1 8682.0
PSMB7 8460.0
NOTCH2 8400.0
PSMB5 8265.0
JAG1 8240.0
PSMD1 8184.0
NCOR1 8153.0
CREBBP 8143.0
PSMD2 8139.0
PSMB3 8005.0
SEL1L 7883.0
PSMA7 7840.0
PSMD11 7775.0
TBL1X 7764.0
B4GALT1 7763.0
PSMD5 7646.0
HES1 7535.0
POFUT1 7528.0
SIRT6 7515.0
PSMB6 7399.0
HDAC7 7388.0
PSMD6 7307.0
PSENEN 7091.0
PSMD12 6820.0
E2F1 6818.0
H2BC5 6759.0
ITCH 6755.0
AKT1 6498.0
HDAC8 6235.0
H2BC17 6188.0
UBC 6135.0
H2BC11 6121.0
AGO2 6087.0
PSMD8 5687.0
HDAC11 5471.0
H2AC6 5440.0
HDAC3 5437.0
TMED2 5345.0
EGF 5267.0
PSMA6 5209.0
YWHAZ 5202.0
PSMC6 4959.0
TBL1XR1 4852.0
PSMC1 4827.0
DLGAP5 4705.0
PSMC2 4543.0
PBX1 4529.0
PTCRA 4488.0
H2AZ1 4378.0
CDK8 4340.0
PSMD3 4297.0
PSMF1 4259.0
RFNG 4095.0
ATP2A1 3981.0
RBX1 3957.0
ARRB1 3956.0
PSMD13 3766.0
ATP2A3 3651.0
SEM1 3454.0
HDAC5 3369.0
SNW1 3347.0
ST3GAL6 3223.0
JUN 3122.0
PSMA1 3111.0
APH1A 2563.0
AGO3 2552.0
H2BC15 2474.0
HDAC10 2431.0
YBX1 2418.0
PSMD7 2084.0
KAT2B 2054.0
PSMB2 1760.0
ELF3 1557.0
FCER2 1492.0
LFNG 1213.0
UBB 1026.0
PSMD14 941.0
PSMC3 916.0
HDAC1 650.0
PSMB4 642.0
PSMC4 605.0
TNRC6A 318.0
TNRC6B 301.0
H2BU1 298.0
HDAC6 243.0
ACTA2 -159.0
TLE1 -278.0
PSMB8 -438.0
IKZF1 -1225.0
FBXW7 -1315.0
WWC1 -2138.0
NEURL1B -2466.0
PSMD10 -2515.0
FLT4 -2628.0
PSMA4 -2764.0
PSMA2 -2823.0
UBA52 -3490.0
PSMB1 -3610.0
GZMB -3740.0
CCND1 -3813.0
CREB1 -3977.0
PSMB10 -4050.0
PSMC5 -4553.0
MIB2 -4725.0
MDK -4787.0
MAMLD1 -4969.0
POGLUT1 -5202.0
ST3GAL3 -5250.0
MIB1 -5272.0
JAG2 -5287.0
PRKCI -5349.0
H2AZ2 -5576.0
H2BC9 -5728.0
MOV10 -5956.0
SKP1 -6297.0
PSEN2 -6393.0
PSMA3 -6433.0
NBEA -6636.0
HDAC2 -6871.0
CCNC -6937.0
MAML2 -7122.0
TNRC6C -7302.0
PSME2 -7327.0
PSMA5 -7476.0
MFNG -7604.0
PSME1 -7778.0
SMAD3 -7868.0
DLL1 -8167.0
TFDP2 -8396.0
DTX1 -8499.0
PSMB9 -8503.0
HDAC9 -8695.0
KAT2A -9063.0
TP53 -9170.0
MYC -9357.0
CUL1 -9420.0
STAT1 -9448.0
RPS27A -9723.0
TLE2 -9911.0


Telomere C-strand (Lagging Strand) Synthesis

Telomere C-strand (Lagging Strand) Synthesis
1217
set Telomere C-strand (Lagging Strand) Synthesis
setSize 34
pANOVA 6.34e-07
s.dist -0.493
p.adjustANOVA 1.04e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
POLD2 -10054
STN1 -9859
POLA1 -9841
RPA1 -9799
CHTF18 -9602
WRN -9501
LIG1 -9469
RFC3 -9405
RPA3 -9220
PRIM1 -9166
RFC4 -8897
CTC1 -8852
POLA2 -7950
RFC5 -7574
PRIM2 -7112
PCNA -7101
FEN1 -6485
DNA2 -6307
DSCC1 -5837
ACD -5673

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
POLD2 -10054
STN1 -9859
POLA1 -9841
RPA1 -9799
CHTF18 -9602
WRN -9501
LIG1 -9469
RFC3 -9405
RPA3 -9220
PRIM1 -9166
RFC4 -8897
CTC1 -8852
POLA2 -7950
RFC5 -7574
PRIM2 -7112
PCNA -7101
FEN1 -6485
DNA2 -6307
DSCC1 -5837
ACD -5673
BLM -5151
RFC1 -5080
RPA2 -4811
POT1 -4708
TERF2 -4421
TERF1 -2831
POLD1 -2573
CHTF8 -124
TEN1 624
TERF2IP 4065
RFC2 5478
TINF2 8502
POLD4 9079
POLD3 10698


Platelet degranulation

Platelet degranulation
829
set Platelet degranulation
setSize 106
pANOVA 7.37e-07
s.dist 0.278
p.adjustANOVA 1.19e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
F5 11434
SERPINA1 11407
QSOX1 11369
CD63 11355
STXBP2 11285
TIMP1 11275
GTPBP2 11180
CYB5R1 11052
TOR4A 11002
FERMT3 10998
CD36 10947
APLP2 10928
ALDOA 10868
CLU 10812
HGF 10417
PECAM1 10414
SCCPDH 10298
ACTN4 10230
TLN1 10191
LHFPL2 9956

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
F5 11434
SERPINA1 11407
QSOX1 11369
CD63 11355
STXBP2 11285
TIMP1 11275
GTPBP2 11180
CYB5R1 11052
TOR4A 11002
FERMT3 10998
CD36 10947
APLP2 10928
ALDOA 10868
CLU 10812
HGF 10417
PECAM1 10414
SCCPDH 10298
ACTN4 10230
TLN1 10191
LHFPL2 9956
CAP1 9934
GAS6 9901
SRGN 9887
WDR1 9868
ACTN1 9811
CFL1 9794
ANXA5 9269
CALU 9049
LAMP2 9034
VTI1B 8933
PSAP 8894
ALB 8630
PFN1 8397
FLNA 8318
TUBA4A 8035
F8 8026
SYTL4 7697
CLEC3B 7525
ITGA2B 7387
HSPA5 7027
APP 6245
VCL 6193
CD109 6110
ECM1 6098
TTN 6088
TGFB2 6083
CD9 5818
VEGFA 5648
VEGFC 5567
TGFB1 5504
SELP 5380
PDGFA 5341
EGF 5267
SERPINE1 5005
PLEK 4699
THBS1 4645
PROS1 4191
VWF 3870
PHACTR2 3743
MMRN1 3618
TIMP3 3154
ITGB3 2944
LY6G6F 2813
TAGLN2 2525
ORM1 2075
MAGED2 1652
ABCC4 1639
F13A1 1493
BRPF3 1249
TF 1246
CHID1 786
RAB27B 774
ORM2 565
CFD 461
MANF 445
PLG 218
PCYOX1L -458
TMSB4X -850
APOOL -867
SPARC -1002
CALM1 -1245
SERPINF2 -1375
ENDOD1 -1464
A1BG -1468
FN1 -1829
PPBP -1960
PF4 -2122
A2M -2133
CTSW -2441
ITIH4 -2921
TMX3 -3613
TEX264 -4024
NHLRC2 -4700
OLA1 -5737
PPIA -6498
SELENOP -6746
TGFB3 -6903
ITIH3 -7066
CDC37L1 -7116
LGALS3BP -7405
SOD1 -7420
SERPING1 -7610
FAM3C -9260
VEGFB -9481
PDGFB -9562
HABP4 -10030


Post-translational protein phosphorylation

Post-translational protein phosphorylation
840
set Post-translational protein phosphorylation
setSize 70
pANOVA 7.43e-07
s.dist 0.342
p.adjustANOVA 1.19e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
FAM20A 11467
F5 11434
SERPINA1 11407
QSOX1 11369
LAMC1 11344
FAM20C 11284
TIMP1 11275
FSTL3 11218
LGALS1 11177
VCAN 11140
PCSK9 11027
APLP2 10928
CKAP4 10819
IGFBP7 10708
NUCB1 10654
PNPLA2 10314
TGOLN2 10307
P4HB 10093
ADAM10 9992
GAS6 9901

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FAM20A 11467
F5 11434
SERPINA1 11407
QSOX1 11369
LAMC1 11344
FAM20C 11284
TIMP1 11275
FSTL3 11218
LGALS1 11177
VCAN 11140
PCSK9 11027
APLP2 10928
CKAP4 10819
IGFBP7 10708
NUCB1 10654
PNPLA2 10314
TGOLN2 10307
P4HB 10093
ADAM10 9992
GAS6 9901
LAMB1 9873
DNAJC3 9831
APOA2 9687
TMEM132A 9453
MELTF 9243
CALU 9049
ALB 8630
SHISA5 8330
SERPIND1 7470
ANO8 6886
PRKCSH 6831
MBTPS1 6492
APP 6245
FUCA2 6028
SERPINA10 5708
PDIA6 5425
ITIH2 5377
CP 4630
ENAM 3683
PROC 3380
C4A 3032
FBN1 2489
APOE 2448
SDC2 2325
MFGE8 1932
FSTL1 1916
CST3 1747
TF 1246
LTBP1 1164
TNC 1095
IGFBP4 122
LAMB2 -47
CSF1 -182
GOLM1 -1299
HSP90B1 -1788
FN1 -1829
FGF23 -1952
KTN1 -2306
APOL1 -3354
C3 -3394
MIA3 -3686
MSLN -3735
PRSS23 -3916
RCN1 -5096
MEN1 -5364
WFS1 -6669
MGAT4A -7072
MXRA8 -7619
IGFBP3 -7733
BMP4 -8762


Extension of Telomeres

Extension of Telomeres
353
set Extension of Telomeres
setSize 51
pANOVA 9.09e-07
s.dist -0.397
p.adjustANOVA 1.44e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
DKC1 -10139
POLD2 -10054
STN1 -9859
POLA1 -9841
RPA1 -9799
CHTF18 -9602
WRN -9501
LIG1 -9469
RFC3 -9405
RPA3 -9220
PRIM1 -9166
RFC4 -8897
CTC1 -8852
RUVBL1 -8098
SHQ1 -8024
POLA2 -7950
RFC5 -7574
GAR1 -7407
PRIM2 -7112
PCNA -7101

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DKC1 -10139
POLD2 -10054
STN1 -9859
POLA1 -9841
RPA1 -9799
CHTF18 -9602
WRN -9501
LIG1 -9469
RFC3 -9405
RPA3 -9220
PRIM1 -9166
RFC4 -8897
CTC1 -8852
RUVBL1 -8098
SHQ1 -8024
POLA2 -7950
RFC5 -7574
GAR1 -7407
PRIM2 -7112
PCNA -7101
NHP2 -6535
FEN1 -6485
DNA2 -6307
WRAP53 -6289
DSCC1 -5837
ANKRD28 -5681
ACD -5673
BLM -5151
RFC1 -5080
RPA2 -4811
TERT -4776
POT1 -4708
TERF2 -4421
CDK2 -3614
TERF1 -2831
POLD1 -2573
RUVBL2 -1097
CHTF8 -124
TEN1 624
CCNA2 1863
PPP6C 2138
PIF1 3426
PPP6R3 3723
TERF2IP 4065
RFC2 5478
RTEL1 6725
CCNA1 7002
TINF2 8502
POLD4 9079
NOP10 10379
POLD3 10698


tRNA processing in the nucleus

tRNA processing in the nucleus
1359
set tRNA processing in the nucleus
setSize 59
pANOVA 9.95e-07
s.dist -0.368
p.adjustANOVA 1.56e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
NDC1 -10077
RPP40 -10069
NUP35 -9726
NUP88 -9668
SEH1L -9574
TSEN2 -8784
RPP25 -8688
RPP30 -8640
TSEN15 -8515
RAN -8475
NUP43 -8368
NUP160 -8357
NUP107 -8285
NUP188 -7953
POP5 -7837
TSEN54 -7696
RPP38 -7683
NUP205 -7516
NUP54 -7131
NUP155 -7061

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NDC1 -10077
RPP40 -10069
NUP35 -9726
NUP88 -9668
SEH1L -9574
TSEN2 -8784
RPP25 -8688
RPP30 -8640
TSEN15 -8515
RAN -8475
NUP43 -8368
NUP160 -8357
NUP107 -8285
NUP188 -7953
POP5 -7837
TSEN54 -7696
RPP38 -7683
NUP205 -7516
NUP54 -7131
NUP155 -7061
DDX1 -6788
NUP93 -6458
XPOT -5659
POP1 -5627
FAM98B -5622
TRNT1 -5539
ELAC2 -5385
NUP133 -5346
C2orf49 -4997
RTRAF -4768
RPP21 -4260
NUP42 -4045
CPSF4 -4025
NUP210 -3949
TPR -3744
NUP85 -3427
AAAS -3332
NUP62 -2410
NUP37 -2275
RPP14 -2204
POM121C -1710
POP7 -1436
RANBP2 -1141
CSTF2 -856
CPSF1 -561
RTCB -467
POM121 -142
POP4 56
NUP153 254
NUP50 2638
ZBTB8OS 4008
RAE1 5007
CLP1 5591
NUP98 5874
SEC13 7506
TSEN34 9433
NUP58 9577
NUP214 10131
RPPH1 10428


COPII-mediated vesicle transport

COPII-mediated vesicle transport
133
set COPII-mediated vesicle transport
setSize 65
pANOVA 1.07e-06
s.dist 0.35
p.adjustANOVA 1.66e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
F5 11434
SERPINA1 11407
TGFA 10983
SEC24D 10803
PREB 10364
RAB1B 10055
RAB1A 9971
CTSZ 9943
NSF 9870
GORASP1 9633
LMAN2 9480
SEC16A 9460
SEC24A 9414
GOLGA2 9412
CTSC 9276
PPP6R1 9179
TRAPPC1 9087
SEC24C 8993
SEC16B 8899
STX5 8547

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
F5 11434
SERPINA1 11407
TGFA 10983
SEC24D 10803
PREB 10364
RAB1B 10055
RAB1A 9971
CTSZ 9943
NSF 9870
GORASP1 9633
LMAN2 9480
SEC16A 9460
SEC24A 9414
GOLGA2 9412
CTSC 9276
PPP6R1 9179
TRAPPC1 9087
SEC24C 8993
SEC16B 8899
STX5 8547
CSNK1D 8475
TFG 8124
F8 8026
COL7A1 7971
YKT6 7621
NAPG 7516
SEC13 7506
SEC24B 7352
SEC23A 7129
SAR1B 6893
NAPA 6660
TRAPPC9 6548
SCFD1 6297
SEC22B 6272
GOSR2 5986
TMED2 5345
MCFD2 5134
TRAPPC3 4443
SEC31A 4346
CD59 4252
CNIH2 4186
TBC1D20 3947
PPP6R3 3723
TRAPPC5 3257
NAPB 3180
TRAPPC10 2565
USO1 2424
AREG 2386
PPP6C 2138
LMAN2L 1586
TRAPPC6B 1327
SEC23IP 737
TRAPPC2L -1855
TRAPPC4 -2490
CNIH1 -2698
SEC22C -3143
TMED10 -4413
CNIH3 -4435
ANKRD28 -5681
BET1 -6342
TRAPPC2 -7043
SEC22A -7808
STX17 -8013
LMAN1 -8522
TRAPPC6A -9543


Signaling by NTRKs

Signaling by NTRKs
1118
set Signaling by NTRKs
setSize 116
pANOVA 1.18e-06
s.dist 0.261
p.adjustANOVA 1.81e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
AP2A1 11340
MAPKAPK3 11249
MAPK1 11193
MAPK14 11115
RPS6KA1 11103
FURIN 10905
GRB2 10733
RIT1 10696
CDK5 10628
RAC1 10624
CRK 10387
DNM2 10373
CLTC 10304
AP2A2 10223
MAP2K1 10148
RALB 10104
MAPK7 10035
LYL1 9959
MEF2A 9891
EP300 9789

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AP2A1 11340
MAPKAPK3 11249
MAPK1 11193
MAPK14 11115
RPS6KA1 11103
FURIN 10905
GRB2 10733
RIT1 10696
CDK5 10628
RAC1 10624
CRK 10387
DNM2 10373
CLTC 10304
AP2A2 10223
MAP2K1 10148
RALB 10104
MAPK7 10035
LYL1 9959
MEF2A 9891
EP300 9789
MAPK3 9750
STAT3 9739
MAPK13 9645
SHC1 9541
ID2 9463
IRS2 9427
RHOA 9401
KIDINS220 9339
SRF 9254
PIK3CB 9126
PTPRO 9048
MAPKAPK2 8852
AP2M1 8799
GAB1 8670
DUSP3 8510
TRIB1 8411
ID1 8155
AP2S1 8045
FOSL1 7839
FRS3 7701
PPP2CB 7451
RAP1A 7335
JUNB 7257
MAP2K2 7222
VRK3 7206
CLTA 7164
MEF2D 7093
PPP2CA 6806
PPP2R5D 6601
PTPN11 6524
PIK3R2 6511
KRAS 6132
PCSK5 6103
DNM1 5998
BAX 5446
CRKL 5250
PPP2R1A 5189
RAPGEF1 5102
NRAS 4907
PCSK6 4846
YWHAB 4721
RPS6KA2 4384
BRAF 4367
ADORA2A 4267
DNM3 3523
NTRK3 2984
AP2B1 2910
FOS 2787
ATF1 2556
TCF12 2381
NAB1 2340
MAP2K5 2256
PIK3CA 2133
EGR3 1815
NELFB 1812
REST 1524
CDK5R1 1363
TF 1246
RPS6KA3 649
CHD4 290
PPP2R1B 89
ATF2 -657
DNAL4 -764
FRS2 -1144
MAPK12 -1261
DUSP4 -2116
FOSB -2206
JUND -2283
DUSP7 -2452
SOS1 -2983
DUSP6 -3055
TIAM1 -3517
NTRK1 -3793
NAB2 -3964
CREB1 -3977
EGR1 -4009
ID3 -4133
SHC2 -4426
MAPK11 -4641
FYN -5211
HRAS -5273
DOCK3 -5299
ELK1 -5884
TPH1 -5977
MEF2C -6025
IRS1 -6033
PTPRS -6062
SGK1 -6264
RALA -6392
SRC -6396
EGR2 -6603
SHC3 -6615
RALGDS -7432
PIK3R1 -8831
RPS6KA5 -9386
PLCG1 -9412


MyD88:MAL(TIRAP) cascade initiated on plasma membrane

MyD88:MAL(TIRAP) cascade initiated on plasma membrane
687
set MyD88:MAL(TIRAP) cascade initiated on plasma membrane
setSize 92
pANOVA 1.56e-06
s.dist 0.29
p.adjustANOVA 2.28e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
MYD88 11331
MAP3K8 11291
MAPKAPK3 11249
S100A12 11206
MAPK1 11193
MAPK14 11115
RPS6KA1 11103
NKIRAS2 11077
MAP2K6 10958
CD36 10947
IRAK3 10909
BTK 10849
TLR2 10535
MAP2K3 10377
MAP2K1 10148
TLR1 10059
MAPK7 10035
NOD2 9983
MEF2A 9891
MAPK3 9750

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MYD88 11331
MAP3K8 11291
MAPKAPK3 11249
S100A12 11206
MAPK1 11193
MAPK14 11115
RPS6KA1 11103
NKIRAS2 11077
MAP2K6 10958
CD36 10947
IRAK3 10909
BTK 10849
TLR2 10535
MAP2K3 10377
MAP2K1 10148
TLR1 10059
MAPK7 10035
NOD2 9983
MEF2A 9891
MAPK3 9750
TLR4 9549
CD14 9466
IKBKG 9441
LY96 9322
PELI3 9118
TLR6 9070
TIRAP 8858
MAPKAPK2 8852
MAPK10 8849
CHUK 8723
DUSP3 8510
IRAK1 7970
TNIP2 7810
MAP2K4 7754
PPP2CB 7451
VRK3 7206
NFKBIB 6845
PPP2CA 6806
TAB3 6655
PPP2R5D 6601
MAP3K1 6286
APP 6245
PELI2 6164
UBC 6135
FBXW11 5621
NFKBIA 5457
PPP2R1A 5189
AGER 4895
PELI1 4802
SOCS1 4688
TRAF6 4673
RPS6KA2 4384
MAP3K7 4043
JUN 3122
NFKB1 2860
FOS 2787
ATF1 2556
ECSIT 2321
TAB2 1975
IKBKB 1759
TAB1 1754
MAP2K7 1550
UBB 1026
RPS6KA3 649
PPP2R1B 89
RELA -204
ATF2 -657
UBE2V1 -1252
S100B -1351
UBE2N -2071
DUSP4 -2116
RIPK2 -2451
DUSP7 -2452
IRAK2 -2799
DUSP6 -3055
UBA52 -3490
NFKB2 -3527
NOD1 -3652
CREB1 -3977
BTRC -4212
MAPK11 -4641
MAPK9 -5454
ELK1 -5884
MEF2C -6025
NKIRAS1 -6234
SKP1 -6297
HMGB1 -6699
SIGIRR -6838
MAPK8 -8929
RPS6KA5 -9386
CUL1 -9420
RPS27A -9723


Toll Like Receptor 2 (TLR2) Cascade

Toll Like Receptor 2 (TLR2) Cascade
1235
set Toll Like Receptor 2 (TLR2) Cascade
setSize 92
pANOVA 1.56e-06
s.dist 0.29
p.adjustANOVA 2.28e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
MYD88 11331
MAP3K8 11291
MAPKAPK3 11249
S100A12 11206
MAPK1 11193
MAPK14 11115
RPS6KA1 11103
NKIRAS2 11077
MAP2K6 10958
CD36 10947
IRAK3 10909
BTK 10849
TLR2 10535
MAP2K3 10377
MAP2K1 10148
TLR1 10059
MAPK7 10035
NOD2 9983
MEF2A 9891
MAPK3 9750

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MYD88 11331
MAP3K8 11291
MAPKAPK3 11249
S100A12 11206
MAPK1 11193
MAPK14 11115
RPS6KA1 11103
NKIRAS2 11077
MAP2K6 10958
CD36 10947
IRAK3 10909
BTK 10849
TLR2 10535
MAP2K3 10377
MAP2K1 10148
TLR1 10059
MAPK7 10035
NOD2 9983
MEF2A 9891
MAPK3 9750
TLR4 9549
CD14 9466
IKBKG 9441
LY96 9322
PELI3 9118
TLR6 9070
TIRAP 8858
MAPKAPK2 8852
MAPK10 8849
CHUK 8723
DUSP3 8510
IRAK1 7970
TNIP2 7810
MAP2K4 7754
PPP2CB 7451
VRK3 7206
NFKBIB 6845
PPP2CA 6806
TAB3 6655
PPP2R5D 6601
MAP3K1 6286
APP 6245
PELI2 6164
UBC 6135
FBXW11 5621
NFKBIA 5457
PPP2R1A 5189
AGER 4895
PELI1 4802
SOCS1 4688
TRAF6 4673
RPS6KA2 4384
MAP3K7 4043
JUN 3122
NFKB1 2860
FOS 2787
ATF1 2556
ECSIT 2321
TAB2 1975
IKBKB 1759
TAB1 1754
MAP2K7 1550
UBB 1026
RPS6KA3 649
PPP2R1B 89
RELA -204
ATF2 -657
UBE2V1 -1252
S100B -1351
UBE2N -2071
DUSP4 -2116
RIPK2 -2451
DUSP7 -2452
IRAK2 -2799
DUSP6 -3055
UBA52 -3490
NFKB2 -3527
NOD1 -3652
CREB1 -3977
BTRC -4212
MAPK11 -4641
MAPK9 -5454
ELK1 -5884
MEF2C -6025
NKIRAS1 -6234
SKP1 -6297
HMGB1 -6699
SIGIRR -6838
MAPK8 -8929
RPS6KA5 -9386
CUL1 -9420
RPS27A -9723


Toll Like Receptor TLR1:TLR2 Cascade

Toll Like Receptor TLR1:TLR2 Cascade
1241
set Toll Like Receptor TLR1:TLR2 Cascade
setSize 92
pANOVA 1.56e-06
s.dist 0.29
p.adjustANOVA 2.28e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
MYD88 11331
MAP3K8 11291
MAPKAPK3 11249
S100A12 11206
MAPK1 11193
MAPK14 11115
RPS6KA1 11103
NKIRAS2 11077
MAP2K6 10958
CD36 10947
IRAK3 10909
BTK 10849
TLR2 10535
MAP2K3 10377
MAP2K1 10148
TLR1 10059
MAPK7 10035
NOD2 9983
MEF2A 9891
MAPK3 9750

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MYD88 11331
MAP3K8 11291
MAPKAPK3 11249
S100A12 11206
MAPK1 11193
MAPK14 11115
RPS6KA1 11103
NKIRAS2 11077
MAP2K6 10958
CD36 10947
IRAK3 10909
BTK 10849
TLR2 10535
MAP2K3 10377
MAP2K1 10148
TLR1 10059
MAPK7 10035
NOD2 9983
MEF2A 9891
MAPK3 9750
TLR4 9549
CD14 9466
IKBKG 9441
LY96 9322
PELI3 9118
TLR6 9070
TIRAP 8858
MAPKAPK2 8852
MAPK10 8849
CHUK 8723
DUSP3 8510
IRAK1 7970
TNIP2 7810
MAP2K4 7754
PPP2CB 7451
VRK3 7206
NFKBIB 6845
PPP2CA 6806
TAB3 6655
PPP2R5D 6601
MAP3K1 6286
APP 6245
PELI2 6164
UBC 6135
FBXW11 5621
NFKBIA 5457
PPP2R1A 5189
AGER 4895
PELI1 4802
SOCS1 4688
TRAF6 4673
RPS6KA2 4384
MAP3K7 4043
JUN 3122
NFKB1 2860
FOS 2787
ATF1 2556
ECSIT 2321
TAB2 1975
IKBKB 1759
TAB1 1754
MAP2K7 1550
UBB 1026
RPS6KA3 649
PPP2R1B 89
RELA -204
ATF2 -657
UBE2V1 -1252
S100B -1351
UBE2N -2071
DUSP4 -2116
RIPK2 -2451
DUSP7 -2452
IRAK2 -2799
DUSP6 -3055
UBA52 -3490
NFKB2 -3527
NOD1 -3652
CREB1 -3977
BTRC -4212
MAPK11 -4641
MAPK9 -5454
ELK1 -5884
MEF2C -6025
NKIRAS1 -6234
SKP1 -6297
HMGB1 -6699
SIGIRR -6838
MAPK8 -8929
RPS6KA5 -9386
CUL1 -9420
RPS27A -9723


Toll Like Receptor TLR6:TLR2 Cascade

Toll Like Receptor TLR6:TLR2 Cascade
1242
set Toll Like Receptor TLR6:TLR2 Cascade
setSize 92
pANOVA 1.56e-06
s.dist 0.29
p.adjustANOVA 2.28e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
MYD88 11331
MAP3K8 11291
MAPKAPK3 11249
S100A12 11206
MAPK1 11193
MAPK14 11115
RPS6KA1 11103
NKIRAS2 11077
MAP2K6 10958
CD36 10947
IRAK3 10909
BTK 10849
TLR2 10535
MAP2K3 10377
MAP2K1 10148
TLR1 10059
MAPK7 10035
NOD2 9983
MEF2A 9891
MAPK3 9750

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MYD88 11331
MAP3K8 11291
MAPKAPK3 11249
S100A12 11206
MAPK1 11193
MAPK14 11115
RPS6KA1 11103
NKIRAS2 11077
MAP2K6 10958
CD36 10947
IRAK3 10909
BTK 10849
TLR2 10535
MAP2K3 10377
MAP2K1 10148
TLR1 10059
MAPK7 10035
NOD2 9983
MEF2A 9891
MAPK3 9750
TLR4 9549
CD14 9466
IKBKG 9441
LY96 9322
PELI3 9118
TLR6 9070
TIRAP 8858
MAPKAPK2 8852
MAPK10 8849
CHUK 8723
DUSP3 8510
IRAK1 7970
TNIP2 7810
MAP2K4 7754
PPP2CB 7451
VRK3 7206
NFKBIB 6845
PPP2CA 6806
TAB3 6655
PPP2R5D 6601
MAP3K1 6286
APP 6245
PELI2 6164
UBC 6135
FBXW11 5621
NFKBIA 5457
PPP2R1A 5189
AGER 4895
PELI1 4802
SOCS1 4688
TRAF6 4673
RPS6KA2 4384
MAP3K7 4043
JUN 3122
NFKB1 2860
FOS 2787
ATF1 2556
ECSIT 2321
TAB2 1975
IKBKB 1759
TAB1 1754
MAP2K7 1550
UBB 1026
RPS6KA3 649
PPP2R1B 89
RELA -204
ATF2 -657
UBE2V1 -1252
S100B -1351
UBE2N -2071
DUSP4 -2116
RIPK2 -2451
DUSP7 -2452
IRAK2 -2799
DUSP6 -3055
UBA52 -3490
NFKB2 -3527
NOD1 -3652
CREB1 -3977
BTRC -4212
MAPK11 -4641
MAPK9 -5454
ELK1 -5884
MEF2C -6025
NKIRAS1 -6234
SKP1 -6297
HMGB1 -6699
SIGIRR -6838
MAPK8 -8929
RPS6KA5 -9386
CUL1 -9420
RPS27A -9723


Cargo recognition for clathrin-mediated endocytosis

Cargo recognition for clathrin-mediated endocytosis
146
set Cargo recognition for clathrin-mediated endocytosis
setSize 90
pANOVA 2.04e-06
s.dist 0.29
p.adjustANOVA 2.95e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
AP2A1 11340
VAMP7 11110
TGFA 10983
ITSN1 10737
GRB2 10733
EPN1 10697
ARRB2 10688
DAB2 10645
LDLR 10634
AGFG1 10514
IGF2R 10494
TGOLN2 10307
CLTC 10304
PICALM 10243
AP2A2 10223
REPS2 10081
CBL 9903
GRK3 9662
SCARB2 9643
SH3GL1 9632

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AP2A1 11340
VAMP7 11110
TGFA 10983
ITSN1 10737
GRB2 10733
EPN1 10697
ARRB2 10688
DAB2 10645
LDLR 10634
AGFG1 10514
IGF2R 10494
TGOLN2 10307
CLTC 10304
PICALM 10243
AP2A2 10223
REPS2 10081
CBL 9903
GRK3 9662
SCARB2 9643
SH3GL1 9632
GRK2 9386
HGS 9317
VAMP3 9311
CLTCL1 9201
TOR1B 9184
TOR1A 8807
AP2M1 8799
COPS7A 8712
EPS15L1 8461
SYT2 8154
AP2S1 8045
CLTB 7968
KIAA0319 7910
NEDD8 7558
STAM2 7431
FCHO2 7311
CLTA 7164
SYT11 6842
ITSN2 6557
UBC 6135
EPS15 6059
NECAP1 5923
SH3KBP1 5885
UBQLN2 5531
SYT1 5438
UBQLN1 5365
EGF 5267
TFRC 4842
LRP2 4295
ARRB1 3956
COPS5 3579
FZD4 3498
AVPR2 3452
CFTR 3091
AP2B1 2910
EPN2 2846
AREG 2386
HBEGF 2064
COPS3 1310
TF 1246
UBB 1026
STON1 956
COPS2 934
STAM 907
VAMP4 607
VAMP8 -139
REPS1 -150
EREG -249
STON2 -635
FCHO1 -1148
EPGN -1241
COPS6 -1242
GPS1 -2376
COPS4 -2731
ADRB2 -3128
AAK1 -3358
UBA52 -3490
COPS7B -3712
NECAP2 -3755
M6PR -4860
DVL2 -5637
SLC2A8 -6202
CD4 -6881
CD3G -8111
CD3D -8297
VAMP2 -8673
COPS8 -8830
RPS27A -9723
LDLRAP1 -10002
IL7R -10153


IRAK4 deficiency (TLR2/4)

IRAK4 deficiency (TLR2/4)
511
set IRAK4 deficiency (TLR2/4)
setSize 10
pANOVA 2.19e-06
s.dist 0.864
p.adjustANOVA 3.11e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
MYD88 11331
CD36 10947
BTK 10849
TLR2 10535
TLR1 10059
TLR4 9549
CD14 9466
LY96 9322
TLR6 9070
TIRAP 8858

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MYD88 11331
CD36 10947
BTK 10849
TLR2 10535
TLR1 10059
TLR4 9549
CD14 9466
LY96 9322
TLR6 9070
TIRAP 8858


MyD88 deficiency (TLR2/4)

MyD88 deficiency (TLR2/4)
684
set MyD88 deficiency (TLR2/4)
setSize 10
pANOVA 2.19e-06
s.dist 0.864
p.adjustANOVA 3.11e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
MYD88 11331
CD36 10947
BTK 10849
TLR2 10535
TLR1 10059
TLR4 9549
CD14 9466
LY96 9322
TLR6 9070
TIRAP 8858

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MYD88 11331
CD36 10947
BTK 10849
TLR2 10535
TLR1 10059
TLR4 9549
CD14 9466
LY96 9322
TLR6 9070
TIRAP 8858


trans-Golgi Network Vesicle Budding

trans-Golgi Network Vesicle Budding
1360
set trans-Golgi Network Vesicle Budding
setSize 69
pANOVA 3.01e-06
s.dist 0.325
p.adjustANOVA 4.22e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
GNS 11410
VAMP7 11110
AP1B1 10872
BLOC1S1 10801
CPD 10712
ARF1 10610
IGF2R 10494
SORT1 10465
DNM2 10373
TGOLN2 10307
CLTC 10304
PICALM 10243
AP1S1 10225
CHMP2A 10205
FTL 10101
CTSZ 9943
RAB5C 9864
AP1M1 9595
OCRL 9323
HGS 9317

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GNS 11410
VAMP7 11110
AP1B1 10872
BLOC1S1 10801
CPD 10712
ARF1 10610
IGF2R 10494
SORT1 10465
DNM2 10373
TGOLN2 10307
CLTC 10304
PICALM 10243
AP1S1 10225
CHMP2A 10205
FTL 10101
CTSZ 9943
RAB5C 9864
AP1M1 9595
OCRL 9323
HGS 9317
GAK 9209
CLTB 7968
AP3B1 7854
SNAPIN 7826
GBF1 7683
SNAP23 7530
AP4M1 7364
PUM1 7329
AP1G1 7318
CLTA 7164
STX4 7026
FTH1 6883
YIPF6 6839
NAPA 6660
SNX2 6471
APP 6245
AP3S1 6030
NECAP1 5923
TBC1D8B 5919
DNASE2 5689
CLINT1 5548
AP4E1 5016
TFRC 4842
ARRB1 3956
TPD52L1 2819
DNAJC6 2611
ACBD3 1983
SNX9 1918
SNX5 1377
BLOC1S3 547
VAMP8 -139
AP4B1 -603
PIK3C2A -1501
AP1S3 -1882
TXNDC5 -2141
BLOC1S6 -2146
DTNBP1 -3372
AP1G2 -3387
GOLGB1 -4004
AP4S1 -4191
M6PR -4860
SH3D19 -6131
BLOC1S4 -6160
AP1M2 -6253
HIP1R -8608
VAMP2 -8673
TPD52 -8806
AP1S2 -8979
HSPA8 -9129


Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)

Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
955
set Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
setSize 81
pANOVA 3.26e-06
s.dist 0.299
p.adjustANOVA 4.53e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
FAM20A 11467
F5 11434
SERPINA1 11407
QSOX1 11369
LAMC1 11344
FAM20C 11284
TIMP1 11275
FSTL3 11218
LGALS1 11177
MMP2 11162
VCAN 11140
PCSK9 11027
APLP2 10928
CKAP4 10819
IGFBP7 10708
NUCB1 10654
PNPLA2 10314
TGOLN2 10307
P4HB 10093
ADAM10 9992

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FAM20A 11467
F5 11434
SERPINA1 11407
QSOX1 11369
LAMC1 11344
FAM20C 11284
TIMP1 11275
FSTL3 11218
LGALS1 11177
MMP2 11162
VCAN 11140
PCSK9 11027
APLP2 10928
CKAP4 10819
IGFBP7 10708
NUCB1 10654
PNPLA2 10314
TGOLN2 10307
P4HB 10093
ADAM10 9992
GAS6 9901
LAMB1 9873
DNAJC3 9831
APOA2 9687
TMEM132A 9453
MELTF 9243
IGFBP6 9106
CALU 9049
ALB 8630
SHISA5 8330
SERPIND1 7470
ANO8 6886
PRKCSH 6831
MBTPS1 6492
APP 6245
FUCA2 6028
SERPINA10 5708
IGFBP2 5601
PDIA6 5425
ITIH2 5377
CP 4630
KLK2 4578
MMP1 3753
ENAM 3683
PROC 3380
C4A 3032
FBN1 2489
APOE 2448
SDC2 2325
MFGE8 1932
FSTL1 1916
CST3 1747
TF 1246
LTBP1 1164
TNC 1095
GZMH 933
PLG 218
IGFBP4 122
LAMB2 -47
CSF1 -182
IGFALS -401
GOLM1 -1299
HSP90B1 -1788
FN1 -1829
FGF23 -1952
KTN1 -2306
APOL1 -3354
C3 -3394
MIA3 -3686
MSLN -3735
PRSS23 -3916
RCN1 -5096
MEN1 -5364
PAPPA -6306
WFS1 -6669
MGAT4A -7072
MXRA8 -7619
IGFBP3 -7733
BMP4 -8762
KLK1 -9072
CTSG -9503


EPHB-mediated forward signaling

EPHB-mediated forward signaling
323
set EPHB-mediated forward signaling
setSize 32
pANOVA 4.14e-06
s.dist 0.47
p.adjustANOVA 5.69e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
ARPC1A 10981
LYN 10810
ARPC1B 10781
ITSN1 10737
RAC1 10624
ACTB 10606
ARPC5 10102
PAK1 10043
CFL1 9794
LIMK2 9689
ACTG1 9678
ARPC4 9592
RHOA 9401
ARPC2 9016
ACTR2 8895
ACTR3 8873
ARPC3 8726
ROCK1 8695
CDC42 8342
LIMK1 8062

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ARPC1A 10981
LYN 10810
ARPC1B 10781
ITSN1 10737
RAC1 10624
ACTB 10606
ARPC5 10102
PAK1 10043
CFL1 9794
LIMK2 9689
ACTG1 9678
ARPC4 9592
RHOA 9401
ARPC2 9016
ACTR2 8895
ACTR3 8873
ARPC3 8726
ROCK1 8695
CDC42 8342
LIMK1 8062
ROCK2 6611
RASA1 6250
WASL 3297
ARHGEF28 2384
SDC2 2325
PTK2 388
YES1 -2846
TIAM1 -3517
FYN -5211
HRAS -5273
SRC -6396
KALRN -8077


tRNA modification in the nucleus and cytosol

tRNA modification in the nucleus and cytosol
1356
set tRNA modification in the nucleus and cytosol
setSize 43
pANOVA 5.03e-06
s.dist -0.402
p.adjustANOVA 6.85e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
ALKBH8 -9977
METTL1 -9815
TRMT11 -9508
TYW1 -9363
QTRT1 -9338
PUS7 -9235
TYW3 -9215
TRMT13 -8669
OSGEP -7996
TP53RK -7907
TPRKB -7836
PUS1 -7669
ADAT2 -7613
THG1L -7403
TRMT61A -7077
THADA -6715
TRMT1 -6407
LCMT2 -6376
EPRS1 -6350
CDKAL1 -5902

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ALKBH8 -9977
METTL1 -9815
TRMT11 -9508
TYW1 -9363
QTRT1 -9338
PUS7 -9235
TYW3 -9215
TRMT13 -8669
OSGEP -7996
TP53RK -7907
TPRKB -7836
PUS1 -7669
ADAT2 -7613
THG1L -7403
TRMT61A -7077
THADA -6715
TRMT1 -6407
LCMT2 -6376
EPRS1 -6350
CDKAL1 -5902
LAGE3 -5360
TRIT1 -5352
FTSJ1 -5188
TRMT44 -5173
TRMT5 -5160
WDR4 -5100
CTU2 -4830
TRMT112 -2296
TRMT12 -1884
URM1 -1729
ADAT1 -1317
TRDMT1 -835
NSUN6 84
PUS3 1168
NSUN2 1256
TYW5 1485
QTRT2 2548
DUS2 2832
ADAT3 5211
CTU1 5266
TRMT10A 6917
TRMT6 8246
TRMT9B 11020


Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.0.2 (2020-06-22)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 18.04.5 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.7.1
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.7.1
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.1.0               GGally_2.0.0               
##  [3] beeswarm_0.2.3              gtools_3.8.2               
##  [5] echarts4r_0.3.2             mitch_1.0.6                
##  [7] MASS_7.3-52                 fgsea_1.14.0               
##  [9] gplots_3.0.3                DESeq2_1.28.1              
## [11] SummarizedExperiment_1.18.1 DelayedArray_0.14.0        
## [13] matrixStats_0.56.0          Biobase_2.48.0             
## [15] GenomicRanges_1.40.0        GenomeInfoDb_1.24.2        
## [17] IRanges_2.22.2              S4Vectors_0.26.1           
## [19] BiocGenerics_0.34.0         reshape2_1.4.4             
## [21] forcats_0.5.0               stringr_1.4.0              
## [23] dplyr_1.0.0                 purrr_0.3.4                
## [25] readr_1.3.1                 tidyr_1.1.0                
## [27] tibble_3.0.1                ggplot2_3.3.2              
## [29] tidyverse_1.3.0            
## 
## loaded via a namespace (and not attached):
##  [1] colorspace_1.4-1       ellipsis_0.3.1         rprojroot_1.3-2       
##  [4] XVector_0.28.0         fs_1.4.2               rstudioapi_0.11       
##  [7] bit64_0.9-7            AnnotationDbi_1.50.1   fansi_0.4.1           
## [10] lubridate_1.7.9        xml2_1.3.2             splines_4.0.2         
## [13] geneplotter_1.66.0     knitr_1.29             jsonlite_1.7.0        
## [16] broom_0.5.6            annotate_1.66.0        dbplyr_1.4.4          
## [19] shiny_1.5.0            compiler_4.0.2         httr_1.4.1            
## [22] backports_1.1.8        assertthat_0.2.1       Matrix_1.2-18         
## [25] fastmap_1.0.1          cli_2.0.2              later_1.1.0.1         
## [28] htmltools_0.5.0        tools_4.0.2            gtable_0.3.0          
## [31] glue_1.4.1             GenomeInfoDbData_1.2.3 fastmatch_1.1-0       
## [34] Rcpp_1.0.4.6           cellranger_1.1.0       vctrs_0.3.1           
## [37] gdata_2.18.0           nlme_3.1-148           xfun_0.15             
## [40] testthat_2.3.2         rvest_0.3.5            mime_0.9              
## [43] lifecycle_0.2.0        XML_3.99-0.3           zlibbioc_1.34.0       
## [46] scales_1.1.1           hms_0.5.3              promises_1.1.1        
## [49] RColorBrewer_1.1-2     yaml_2.2.1             memoise_1.1.0         
## [52] gridExtra_2.3          reshape_0.8.8          stringi_1.4.6         
## [55] RSQLite_2.2.0          highr_0.8              genefilter_1.70.0     
## [58] desc_1.2.0             caTools_1.18.0         BiocParallel_1.22.0   
## [61] rlang_0.4.6            pkgconfig_2.0.3        bitops_1.0-6          
## [64] evaluate_0.14          lattice_0.20-41        htmlwidgets_1.5.1     
## [67] bit_1.1-15.2           tidyselect_1.1.0       plyr_1.8.6            
## [70] magrittr_1.5           R6_2.4.1               generics_0.0.2        
## [73] DBI_1.1.0              pillar_1.4.4           haven_2.3.1           
## [76] withr_2.2.0            survival_3.2-3         RCurl_1.98-1.2        
## [79] modelr_0.1.8           crayon_1.3.4           KernSmooth_2.23-17    
## [82] rmarkdown_2.3          locfit_1.5-9.4         grid_4.0.2            
## [85] readxl_1.3.1           data.table_1.12.8      blob_1.2.1            
## [88] reprex_0.3.0           digest_0.6.25          pbmcapply_1.5.0       
## [91] xtable_1.8-4           httpuv_1.5.4           munsell_0.5.0

END of report