Mitch Report
Antony Kaspi & Mark Ziemann
date generated: 2020-09-10
Background
Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch
Input profiles
Here is the first few lines of the input profile.
## x
## A1BG -3.3462109
## A1BG-AS1 -0.1855420
## A1CF 0.1865445
## A2M 1.3466992
## A2M-AS1 0.8962988
## A2ML1 1.9364758Here are some metrics about the input data profile:
| Profile metrics | |
|---|---|
| num_genesets | 2400 |
| num_genes_in_profile | 22124 |
| duplicated_genes_present | 0 |
| num_profile_genes_in_sets | 8472 |
| num_profile_genes_not_in_sets | 13652 |
Here is a plot of the input profiles. Note the dynamic ranges. 
Here is the contour plot of the profile including all detected genes.
Input genesets
Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt
| Gene sets metrics | |
|---|---|
| num_genesets | 2400 |
| num_genesets_excluded | 1035 |
| num_genesets_included | 1365 |
Differential pathway expression
Interactive enrichment scatterplot
Significance is calculated by -log10(p-value). All points shown are FDR<0.05.
Results table
Top N= 100 gene sets
| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| Peptide chain elongation | 88 | 6.99e-40 | -0.814 | 3.18e-37 |
| Eukaryotic Translation Elongation | 93 | 7.24e-42 | -0.812 | 9.88e-39 |
| Viral mRNA Translation | 88 | 1.33e-37 | -0.789 | 3.63e-35 |
| Formation of a pool of free 40S subunits | 100 | 1.06e-40 | -0.771 | 7.21e-38 |
| Eukaryotic Translation Termination | 92 | 5.98e-37 | -0.765 | 1.36e-34 |
| Selenocysteine synthesis | 92 | 2.25e-36 | -0.758 | 3.57e-34 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | 94 | 3.77e-34 | -0.726 | 4.29e-32 |
| L13a-mediated translational silencing of Ceruloplasmin expression | 110 | 1.10e-37 | -0.707 | 3.63e-35 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | 111 | 2.36e-36 | -0.691 | 3.57e-34 |
| VLDLR internalisation and degradation | 11 | 8.08e-05 | -0.686 | 8.80e-04 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | 100 | 6.51e-31 | -0.668 | 6.35e-29 |
| Cap-dependent Translation Initiation | 118 | 9.58e-36 | -0.664 | 1.19e-33 |
| Eukaryotic Translation Initiation | 118 | 9.58e-36 | -0.664 | 1.19e-33 |
| Formation of the ternary complex, and subsequently, the 43S complex | 51 | 3.04e-15 | -0.638 | 1.01e-13 |
| Josephin domain DUBs | 10 | 5.53e-04 | -0.631 | 4.29e-03 |
| SRP-dependent cotranslational protein targeting to membrane | 111 | 7.47e-30 | -0.623 | 6.80e-28 |
| Formation of ATP by chemiosmotic coupling | 18 | 7.32e-06 | -0.610 | 1.22e-04 |
| WNT5A-dependent internalization of FZD4 | 13 | 1.51e-04 | -0.607 | 1.48e-03 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | 114 | 1.58e-28 | -0.600 | 1.27e-26 |
| Nonsense-Mediated Decay (NMD) | 114 | 1.58e-28 | -0.600 | 1.27e-26 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | 59 | 2.49e-15 | -0.595 | 8.50e-14 |
| Translation initiation complex formation | 58 | 5.85e-15 | -0.592 | 1.90e-13 |
| Ribosomal scanning and start codon recognition | 58 | 1.22e-14 | -0.585 | 3.88e-13 |
| Selenoamino acid metabolism | 114 | 6.78e-27 | -0.581 | 4.62e-25 |
| Influenza Viral RNA Transcription and Replication | 135 | 1.32e-26 | -0.531 | 8.57e-25 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | 16 | 2.49e-04 | -0.529 | 2.16e-03 |
| NF-kB is activated and signals survival | 12 | 1.51e-03 | -0.529 | 9.39e-03 |
| Pexophagy | 11 | 2.77e-03 | -0.521 | 1.49e-02 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | 11 | 2.84e-03 | -0.520 | 1.51e-02 |
| GP1b-IX-V activation signalling | 10 | 4.61e-03 | -0.517 | 2.07e-02 |
| Glycogen storage diseases | 13 | 1.39e-03 | -0.512 | 8.75e-03 |
| tRNA processing in the mitochondrion | 32 | 5.58e-07 | -0.511 | 1.19e-05 |
| Trafficking of GluR2-containing AMPA receptors | 12 | 2.63e-03 | -0.501 | 1.43e-02 |
| Regulation of expression of SLITs and ROBOs | 162 | 5.02e-28 | -0.499 | 3.81e-26 |
| Glycogen synthesis | 13 | 2.01e-03 | -0.495 | 1.18e-02 |
| RNA Polymerase I Promoter Opening | 19 | 2.15e-04 | -0.490 | 1.91e-03 |
| Pausing and recovery of Tat-mediated HIV elongation | 30 | 3.45e-06 | -0.490 | 6.30e-05 |
| Tat-mediated HIV elongation arrest and recovery | 30 | 3.45e-06 | -0.490 | 6.30e-05 |
| Hyaluronan uptake and degradation | 10 | 9.15e-03 | -0.476 | 3.24e-02 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | 21 | 1.67e-04 | -0.474 | 1.62e-03 |
| Diseases of carbohydrate metabolism | 29 | 9.84e-06 | -0.474 | 1.54e-04 |
| Assembly Of The HIV Virion | 15 | 1.48e-03 | -0.474 | 9.20e-03 |
| Advanced glycosylation endproduct receptor signaling | 12 | 4.47e-03 | -0.474 | 2.03e-02 |
| EGFR downregulation | 27 | 3.15e-05 | -0.463 | 3.98e-04 |
| Retrograde neurotrophin signalling | 12 | 5.70e-03 | -0.461 | 2.39e-02 |
| Heparan sulfate/heparin (HS-GAG) metabolism | 38 | 9.09e-07 | -0.460 | 1.88e-05 |
| Influenza Infection | 154 | 8.95e-23 | -0.458 | 3.82e-21 |
| SUMOylation of immune response proteins | 11 | 9.22e-03 | -0.453 | 3.25e-02 |
| Cytosolic iron-sulfur cluster assembly | 13 | 5.00e-03 | -0.450 | 2.18e-02 |
| Spry regulation of FGF signaling | 16 | 1.88e-03 | -0.449 | 1.10e-02 |
| Cristae formation | 31 | 1.52e-05 | -0.449 | 2.19e-04 |
| The role of Nef in HIV-1 replication and disease pathogenesis | 28 | 4.32e-05 | -0.446 | 5.21e-04 |
| Signal regulatory protein family interactions | 12 | 8.10e-03 | -0.441 | 3.00e-02 |
| PKA activation in glucagon signalling | 14 | 4.68e-03 | -0.436 | 2.08e-02 |
| DNA methylation | 20 | 7.27e-04 | -0.436 | 5.30e-03 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | 23 | 2.95e-04 | -0.436 | 2.50e-03 |
| Hyaluronan metabolism | 13 | 6.66e-03 | -0.435 | 2.64e-02 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | 23 | 3.15e-04 | -0.434 | 2.66e-03 |
| ERBB2 Regulates Cell Motility | 10 | 1.75e-02 | -0.434 | 5.38e-02 |
| HS-GAG degradation | 16 | 2.73e-03 | -0.433 | 1.47e-02 |
| Olfactory Signaling Pathway | 61 | 5.25e-09 | 0.432 | 1.41e-07 |
| Complex I biogenesis | 55 | 3.44e-08 | -0.430 | 7.84e-07 |
| Pentose phosphate pathway | 13 | 7.39e-03 | -0.429 | 2.82e-02 |
| Signaling by ROBO receptors | 202 | 8.29e-26 | -0.428 | 4.53e-24 |
| Interleukin-2 signaling | 11 | 1.41e-02 | -0.428 | 4.62e-02 |
| RHO GTPases Activate NADPH Oxidases | 21 | 7.22e-04 | -0.426 | 5.30e-03 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | 22 | 5.50e-04 | -0.425 | 4.29e-03 |
| Gluconeogenesis | 28 | 1.02e-04 | -0.424 | 1.08e-03 |
| Common Pathway of Fibrin Clot Formation | 14 | 6.07e-03 | -0.424 | 2.47e-02 |
| Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | 124 | 4.77e-16 | -0.422 | 1.71e-14 |
| rRNA processing in the mitochondrion | 29 | 9.62e-05 | -0.418 | 1.03e-03 |
| GAB1 signalosome | 15 | 5.10e-03 | -0.418 | 2.20e-02 |
| AKT phosphorylates targets in the nucleus | 10 | 2.23e-02 | -0.417 | 6.50e-02 |
| A tetrasaccharide linker sequence is required for GAG synthesis | 18 | 2.21e-03 | -0.417 | 1.25e-02 |
| FOXO-mediated transcription of cell death genes | 16 | 3.99e-03 | -0.416 | 1.89e-02 |
| HIV elongation arrest and recovery | 32 | 4.99e-05 | -0.414 | 5.92e-04 |
| Pausing and recovery of HIV elongation | 32 | 4.99e-05 | -0.414 | 5.92e-04 |
| CDC6 association with the ORC:origin complex | 11 | 1.75e-02 | 0.414 | 5.38e-02 |
| Membrane binding and targetting of GAG proteins | 13 | 9.89e-03 | -0.413 | 3.46e-02 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | 13 | 9.89e-03 | -0.413 | 3.46e-02 |
| Downregulation of ERBB2:ERBB3 signaling | 12 | 1.36e-02 | -0.411 | 4.48e-02 |
| p75NTR signals via NF-kB | 15 | 5.86e-03 | -0.411 | 2.45e-02 |
| PKA activation | 15 | 6.26e-03 | -0.408 | 2.55e-02 |
| Mucopolysaccharidoses | 11 | 1.93e-02 | -0.407 | 5.75e-02 |
| Downregulation of ERBB2 signaling | 24 | 5.56e-04 | -0.407 | 4.29e-03 |
| Uptake and function of anthrax toxins | 10 | 2.63e-02 | -0.406 | 7.30e-02 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | 14 | 8.62e-03 | -0.405 | 3.14e-02 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | 14 | 8.62e-03 | -0.405 | 3.14e-02 |
| Acetylcholine Neurotransmitter Release Cycle | 11 | 1.99e-02 | -0.405 | 5.89e-02 |
| Respiratory electron transport | 101 | 2.67e-12 | -0.403 | 7.58e-11 |
| Plasma lipoprotein clearance | 29 | 1.77e-04 | -0.402 | 1.69e-03 |
| rRNA processing | 219 | 1.92e-24 | -0.400 | 8.75e-23 |
| rRNA processing in the nucleus and cytosol | 190 | 4.77e-21 | -0.396 | 1.97e-19 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | 26 | 4.86e-04 | 0.395 | 3.90e-03 |
| Chondroitin sulfate/dermatan sulfate metabolism | 39 | 2.01e-05 | -0.394 | 2.72e-04 |
| Major pathway of rRNA processing in the nucleolus and cytosol | 180 | 7.14e-20 | -0.394 | 2.78e-18 |
| Regulation of localization of FOXO transcription factors | 12 | 1.93e-02 | -0.390 | 5.75e-02 |
| Cleavage of the damaged purine | 24 | 9.56e-04 | -0.389 | 6.43e-03 |
| Depurination | 24 | 9.56e-04 | -0.389 | 6.43e-03 |
| Recognition and association of DNA glycosylase with site containing an affected purine | 24 | 9.56e-04 | -0.389 | 6.43e-03 |
Results (complete table)
Click HERE to show results for all gene sets
| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| Peptide chain elongation | 88 | 6.99e-40 | -0.814000 | 3.18e-37 |
| Eukaryotic Translation Elongation | 93 | 7.24e-42 | -0.812000 | 9.88e-39 |
| Viral mRNA Translation | 88 | 1.33e-37 | -0.789000 | 3.63e-35 |
| Formation of a pool of free 40S subunits | 100 | 1.06e-40 | -0.771000 | 7.21e-38 |
| Eukaryotic Translation Termination | 92 | 5.98e-37 | -0.765000 | 1.36e-34 |
| Selenocysteine synthesis | 92 | 2.25e-36 | -0.758000 | 3.57e-34 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | 94 | 3.77e-34 | -0.726000 | 4.29e-32 |
| L13a-mediated translational silencing of Ceruloplasmin expression | 110 | 1.10e-37 | -0.707000 | 3.63e-35 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | 111 | 2.36e-36 | -0.691000 | 3.57e-34 |
| VLDLR internalisation and degradation | 11 | 8.08e-05 | -0.686000 | 8.80e-04 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | 100 | 6.51e-31 | -0.668000 | 6.35e-29 |
| Cap-dependent Translation Initiation | 118 | 9.58e-36 | -0.664000 | 1.19e-33 |
| Eukaryotic Translation Initiation | 118 | 9.58e-36 | -0.664000 | 1.19e-33 |
| Formation of the ternary complex, and subsequently, the 43S complex | 51 | 3.04e-15 | -0.638000 | 1.01e-13 |
| Josephin domain DUBs | 10 | 5.53e-04 | -0.631000 | 4.29e-03 |
| SRP-dependent cotranslational protein targeting to membrane | 111 | 7.47e-30 | -0.623000 | 6.80e-28 |
| Formation of ATP by chemiosmotic coupling | 18 | 7.32e-06 | -0.610000 | 1.22e-04 |
| WNT5A-dependent internalization of FZD4 | 13 | 1.51e-04 | -0.607000 | 1.48e-03 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | 114 | 1.58e-28 | -0.600000 | 1.27e-26 |
| Nonsense-Mediated Decay (NMD) | 114 | 1.58e-28 | -0.600000 | 1.27e-26 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | 59 | 2.49e-15 | -0.595000 | 8.50e-14 |
| Translation initiation complex formation | 58 | 5.85e-15 | -0.592000 | 1.90e-13 |
| Ribosomal scanning and start codon recognition | 58 | 1.22e-14 | -0.585000 | 3.88e-13 |
| Selenoamino acid metabolism | 114 | 6.78e-27 | -0.581000 | 4.62e-25 |
| Influenza Viral RNA Transcription and Replication | 135 | 1.32e-26 | -0.531000 | 8.57e-25 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | 16 | 2.49e-04 | -0.529000 | 2.16e-03 |
| NF-kB is activated and signals survival | 12 | 1.51e-03 | -0.529000 | 9.39e-03 |
| Pexophagy | 11 | 2.77e-03 | -0.521000 | 1.49e-02 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | 11 | 2.84e-03 | -0.520000 | 1.51e-02 |
| GP1b-IX-V activation signalling | 10 | 4.61e-03 | -0.517000 | 2.07e-02 |
| Glycogen storage diseases | 13 | 1.39e-03 | -0.512000 | 8.75e-03 |
| tRNA processing in the mitochondrion | 32 | 5.58e-07 | -0.511000 | 1.19e-05 |
| Trafficking of GluR2-containing AMPA receptors | 12 | 2.63e-03 | -0.501000 | 1.43e-02 |
| Regulation of expression of SLITs and ROBOs | 162 | 5.02e-28 | -0.499000 | 3.81e-26 |
| Glycogen synthesis | 13 | 2.01e-03 | -0.495000 | 1.18e-02 |
| RNA Polymerase I Promoter Opening | 19 | 2.15e-04 | -0.490000 | 1.91e-03 |
| Pausing and recovery of Tat-mediated HIV elongation | 30 | 3.45e-06 | -0.490000 | 6.30e-05 |
| Tat-mediated HIV elongation arrest and recovery | 30 | 3.45e-06 | -0.490000 | 6.30e-05 |
| Hyaluronan uptake and degradation | 10 | 9.15e-03 | -0.476000 | 3.24e-02 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | 21 | 1.67e-04 | -0.474000 | 1.62e-03 |
| Diseases of carbohydrate metabolism | 29 | 9.84e-06 | -0.474000 | 1.54e-04 |
| Assembly Of The HIV Virion | 15 | 1.48e-03 | -0.474000 | 9.20e-03 |
| Advanced glycosylation endproduct receptor signaling | 12 | 4.47e-03 | -0.474000 | 2.03e-02 |
| EGFR downregulation | 27 | 3.15e-05 | -0.463000 | 3.98e-04 |
| Retrograde neurotrophin signalling | 12 | 5.70e-03 | -0.461000 | 2.39e-02 |
| Heparan sulfate/heparin (HS-GAG) metabolism | 38 | 9.09e-07 | -0.460000 | 1.88e-05 |
| Influenza Infection | 154 | 8.95e-23 | -0.458000 | 3.82e-21 |
| SUMOylation of immune response proteins | 11 | 9.22e-03 | -0.453000 | 3.25e-02 |
| Cytosolic iron-sulfur cluster assembly | 13 | 5.00e-03 | -0.450000 | 2.18e-02 |
| Spry regulation of FGF signaling | 16 | 1.88e-03 | -0.449000 | 1.10e-02 |
| Cristae formation | 31 | 1.52e-05 | -0.449000 | 2.19e-04 |
| The role of Nef in HIV-1 replication and disease pathogenesis | 28 | 4.32e-05 | -0.446000 | 5.21e-04 |
| Signal regulatory protein family interactions | 12 | 8.10e-03 | -0.441000 | 3.00e-02 |
| PKA activation in glucagon signalling | 14 | 4.68e-03 | -0.436000 | 2.08e-02 |
| DNA methylation | 20 | 7.27e-04 | -0.436000 | 5.30e-03 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | 23 | 2.95e-04 | -0.436000 | 2.50e-03 |
| Hyaluronan metabolism | 13 | 6.66e-03 | -0.435000 | 2.64e-02 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | 23 | 3.15e-04 | -0.434000 | 2.66e-03 |
| ERBB2 Regulates Cell Motility | 10 | 1.75e-02 | -0.434000 | 5.38e-02 |
| HS-GAG degradation | 16 | 2.73e-03 | -0.433000 | 1.47e-02 |
| Olfactory Signaling Pathway | 61 | 5.25e-09 | 0.432000 | 1.41e-07 |
| Complex I biogenesis | 55 | 3.44e-08 | -0.430000 | 7.84e-07 |
| Pentose phosphate pathway | 13 | 7.39e-03 | -0.429000 | 2.82e-02 |
| Signaling by ROBO receptors | 202 | 8.29e-26 | -0.428000 | 4.53e-24 |
| Interleukin-2 signaling | 11 | 1.41e-02 | -0.428000 | 4.62e-02 |
| RHO GTPases Activate NADPH Oxidases | 21 | 7.22e-04 | -0.426000 | 5.30e-03 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | 22 | 5.50e-04 | -0.425000 | 4.29e-03 |
| Gluconeogenesis | 28 | 1.02e-04 | -0.424000 | 1.08e-03 |
| Common Pathway of Fibrin Clot Formation | 14 | 6.07e-03 | -0.424000 | 2.47e-02 |
| Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | 124 | 4.77e-16 | -0.422000 | 1.71e-14 |
| rRNA processing in the mitochondrion | 29 | 9.62e-05 | -0.418000 | 1.03e-03 |
| GAB1 signalosome | 15 | 5.10e-03 | -0.418000 | 2.20e-02 |
| AKT phosphorylates targets in the nucleus | 10 | 2.23e-02 | -0.417000 | 6.50e-02 |
| A tetrasaccharide linker sequence is required for GAG synthesis | 18 | 2.21e-03 | -0.417000 | 1.25e-02 |
| FOXO-mediated transcription of cell death genes | 16 | 3.99e-03 | -0.416000 | 1.89e-02 |
| HIV elongation arrest and recovery | 32 | 4.99e-05 | -0.414000 | 5.92e-04 |
| Pausing and recovery of HIV elongation | 32 | 4.99e-05 | -0.414000 | 5.92e-04 |
| CDC6 association with the ORC:origin complex | 11 | 1.75e-02 | 0.414000 | 5.38e-02 |
| Membrane binding and targetting of GAG proteins | 13 | 9.89e-03 | -0.413000 | 3.46e-02 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | 13 | 9.89e-03 | -0.413000 | 3.46e-02 |
| Downregulation of ERBB2:ERBB3 signaling | 12 | 1.36e-02 | -0.411000 | 4.48e-02 |
| p75NTR signals via NF-kB | 15 | 5.86e-03 | -0.411000 | 2.45e-02 |
| PKA activation | 15 | 6.26e-03 | -0.408000 | 2.55e-02 |
| Mucopolysaccharidoses | 11 | 1.93e-02 | -0.407000 | 5.75e-02 |
| Downregulation of ERBB2 signaling | 24 | 5.56e-04 | -0.407000 | 4.29e-03 |
| Uptake and function of anthrax toxins | 10 | 2.63e-02 | -0.406000 | 7.30e-02 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | 14 | 8.62e-03 | -0.405000 | 3.14e-02 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | 14 | 8.62e-03 | -0.405000 | 3.14e-02 |
| Acetylcholine Neurotransmitter Release Cycle | 11 | 1.99e-02 | -0.405000 | 5.89e-02 |
| Respiratory electron transport | 101 | 2.67e-12 | -0.403000 | 7.58e-11 |
| Plasma lipoprotein clearance | 29 | 1.77e-04 | -0.402000 | 1.69e-03 |
| rRNA processing | 219 | 1.92e-24 | -0.400000 | 8.75e-23 |
| rRNA processing in the nucleus and cytosol | 190 | 4.77e-21 | -0.396000 | 1.97e-19 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | 26 | 4.86e-04 | 0.395000 | 3.90e-03 |
| Chondroitin sulfate/dermatan sulfate metabolism | 39 | 2.01e-05 | -0.394000 | 2.72e-04 |
| Major pathway of rRNA processing in the nucleolus and cytosol | 180 | 7.14e-20 | -0.394000 | 2.78e-18 |
| Regulation of localization of FOXO transcription factors | 12 | 1.93e-02 | -0.390000 | 5.75e-02 |
| Cleavage of the damaged purine | 24 | 9.56e-04 | -0.389000 | 6.43e-03 |
| Depurination | 24 | 9.56e-04 | -0.389000 | 6.43e-03 |
| Recognition and association of DNA glycosylase with site containing an affected purine | 24 | 9.56e-04 | -0.389000 | 6.43e-03 |
| HS-GAG biosynthesis | 20 | 2.81e-03 | -0.386000 | 1.50e-02 |
| Inhibition of DNA recombination at telomere | 35 | 7.84e-05 | -0.386000 | 8.70e-04 |
| Late endosomal microautophagy | 30 | 2.58e-04 | -0.385000 | 2.22e-03 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | 20 | 2.94e-03 | -0.384000 | 1.54e-02 |
| Antimicrobial peptides | 34 | 1.15e-04 | -0.382000 | 1.19e-03 |
| Regulation of TP53 Activity through Association with Co-factors | 12 | 2.27e-02 | -0.380000 | 6.56e-02 |
| Gap junction trafficking | 14 | 1.43e-02 | -0.378000 | 4.64e-02 |
| EPH-ephrin mediated repulsion of cells | 40 | 3.49e-05 | -0.378000 | 4.33e-04 |
| Negative regulation of FGFR4 signaling | 21 | 2.70e-03 | -0.378000 | 1.46e-02 |
| Regulation of FZD by ubiquitination | 16 | 8.93e-03 | -0.378000 | 3.19e-02 |
| Packaging Of Telomere Ends | 20 | 3.47e-03 | -0.377000 | 1.74e-02 |
| Insulin receptor recycling | 21 | 2.90e-03 | -0.375000 | 1.53e-02 |
| Activated NOTCH1 Transmits Signal to the Nucleus | 27 | 7.72e-04 | -0.374000 | 5.54e-03 |
| Synthesis of PIPs at the late endosome membrane | 11 | 3.19e-02 | 0.374000 | 8.52e-02 |
| Pre-NOTCH Processing in Golgi | 18 | 6.35e-03 | -0.372000 | 2.56e-02 |
| Defective B3GAT3 causes JDSSDHD | 12 | 2.59e-02 | -0.371000 | 7.25e-02 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | 12 | 2.62e-02 | -0.371000 | 7.30e-02 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | 16 | 1.05e-02 | -0.369000 | 3.66e-02 |
| Presynaptic phase of homologous DNA pairing and strand exchange | 39 | 6.83e-05 | 0.368000 | 7.70e-04 |
| PIWI-interacting RNA (piRNA) biogenesis | 24 | 1.81e-03 | -0.368000 | 1.08e-02 |
| Chondroitin sulfate biosynthesis | 13 | 2.26e-02 | -0.365000 | 6.54e-02 |
| Class C/3 (Metabotropic glutamate/pheromone receptors) | 11 | 3.66e-02 | 0.364000 | 9.40e-02 |
| Amyloid fiber formation | 51 | 8.10e-06 | -0.361000 | 1.33e-04 |
| Negative regulation of FGFR3 signaling | 20 | 5.32e-03 | -0.360000 | 2.28e-02 |
| ERKs are inactivated | 13 | 2.47e-02 | -0.360000 | 6.95e-02 |
| Signaling by NODAL | 13 | 2.54e-02 | -0.358000 | 7.13e-02 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | 32 | 4.58e-04 | -0.358000 | 3.70e-03 |
| Diseases of programmed cell death | 22 | 3.67e-03 | -0.358000 | 1.79e-02 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | 22 | 3.81e-03 | -0.356000 | 1.83e-02 |
| Lysosome Vesicle Biogenesis | 32 | 5.11e-04 | -0.355000 | 4.05e-03 |
| Other semaphorin interactions | 16 | 1.41e-02 | -0.355000 | 4.62e-02 |
| Detoxification of Reactive Oxygen Species | 32 | 5.24e-04 | -0.354000 | 4.13e-03 |
| Pyrimidine salvage | 10 | 5.25e-02 | -0.354000 | 1.23e-01 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | 12 | 3.37e-02 | -0.354000 | 8.79e-02 |
| Diseases of hemostasis | 12 | 3.37e-02 | -0.354000 | 8.79e-02 |
| Formation of Fibrin Clot (Clotting Cascade) | 26 | 1.85e-03 | -0.353000 | 1.10e-02 |
| Homologous DNA Pairing and Strand Exchange | 42 | 8.09e-05 | 0.351000 | 8.80e-04 |
| Response of Mtb to phagocytosis | 22 | 4.35e-03 | -0.351000 | 1.99e-02 |
| Signaling by Leptin | 10 | 5.47e-02 | -0.351000 | 1.27e-01 |
| PINK1-PRKN Mediated Mitophagy | 21 | 5.41e-03 | -0.351000 | 2.29e-02 |
| Norepinephrine Neurotransmitter Release Cycle | 13 | 2.91e-02 | -0.350000 | 7.92e-02 |
| Condensation of Prometaphase Chromosomes | 11 | 4.48e-02 | 0.349000 | 1.09e-01 |
| Glycosaminoglycan metabolism | 93 | 6.86e-09 | -0.348000 | 1.77e-07 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | 20 | 7.16e-03 | -0.347000 | 2.75e-02 |
| Neurodegenerative Diseases | 20 | 7.16e-03 | -0.347000 | 2.75e-02 |
| Translation | 295 | 1.06e-24 | -0.347000 | 4.97e-23 |
| Suppression of phagosomal maturation | 12 | 3.79e-02 | -0.346000 | 9.63e-02 |
| Glycogen metabolism | 23 | 4.20e-03 | -0.345000 | 1.97e-02 |
| Constitutive Signaling by AKT1 E17K in Cancer | 26 | 2.45e-03 | -0.343000 | 1.35e-02 |
| Mitophagy | 28 | 1.67e-03 | -0.343000 | 1.01e-02 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | 27 | 2.04e-03 | -0.343000 | 1.18e-02 |
| Nef mediated downregulation of MHC class I complex cell surface expression | 10 | 6.06e-02 | -0.343000 | 1.37e-01 |
| Ephrin signaling | 18 | 1.19e-02 | -0.342000 | 4.02e-02 |
| Activation of Matrix Metalloproteinases | 24 | 3.93e-03 | -0.340000 | 1.87e-02 |
| Senescence-Associated Secretory Phenotype (SASP) | 66 | 1.94e-06 | -0.339000 | 3.79e-05 |
| LDL clearance | 17 | 1.57e-02 | -0.338000 | 5.01e-02 |
| Collagen degradation | 29 | 1.61e-03 | -0.338000 | 9.81e-03 |
| HSF1-dependent transactivation | 29 | 1.70e-03 | -0.337000 | 1.02e-02 |
| Defective B4GALT7 causes EDS, progeroid type | 12 | 4.39e-02 | -0.336000 | 1.07e-01 |
| p75NTR recruits signalling complexes | 12 | 4.49e-02 | -0.334000 | 1.09e-01 |
| Signaling by FGFR2 IIIa TM | 18 | 1.41e-02 | -0.334000 | 4.62e-02 |
| SUMOylation of DNA methylation proteins | 16 | 2.07e-02 | -0.334000 | 6.09e-02 |
| CS/DS degradation | 10 | 6.77e-02 | -0.334000 | 1.49e-01 |
| Smooth Muscle Contraction | 31 | 1.31e-03 | -0.334000 | 8.29e-03 |
| Adenylate cyclase inhibitory pathway | 11 | 5.73e-02 | -0.331000 | 1.31e-01 |
| Neutrophil degranulation | 459 | 5.38e-34 | -0.330000 | 5.65e-32 |
| ROS and RNS production in phagocytes | 31 | 1.52e-03 | -0.329000 | 9.40e-03 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | 29 | 2.18e-03 | -0.329000 | 1.25e-02 |
| The citric acid (TCA) cycle and respiratory electron transport | 172 | 1.01e-13 | -0.329000 | 3.06e-12 |
| PKA-mediated phosphorylation of CREB | 17 | 1.92e-02 | -0.328000 | 5.75e-02 |
| AKT phosphorylates targets in the cytosol | 14 | 3.47e-02 | -0.326000 | 8.98e-02 |
| Chaperone Mediated Autophagy | 20 | 1.21e-02 | -0.324000 | 4.06e-02 |
| Collagen biosynthesis and modifying enzymes | 46 | 1.44e-04 | -0.324000 | 1.42e-03 |
| N-Glycan antennae elongation | 13 | 4.32e-02 | -0.324000 | 1.07e-01 |
| CaM pathway | 27 | 3.62e-03 | -0.324000 | 1.78e-02 |
| Calmodulin induced events | 27 | 3.62e-03 | -0.324000 | 1.78e-02 |
| Interferon alpha/beta signaling | 57 | 2.54e-05 | 0.322000 | 3.27e-04 |
| Glycosphingolipid metabolism | 36 | 8.34e-04 | -0.322000 | 5.81e-03 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | 22 | 9.15e-03 | -0.321000 | 3.24e-02 |
| NRIF signals cell death from the nucleus | 15 | 3.14e-02 | -0.321000 | 8.40e-02 |
| PI3K events in ERBB2 signaling | 11 | 6.54e-02 | -0.321000 | 1.46e-01 |
| Ca-dependent events | 29 | 2.82e-03 | -0.320000 | 1.50e-02 |
| RMTs methylate histone arginines | 37 | 7.44e-04 | -0.320000 | 5.40e-03 |
| TBC/RABGAPs | 45 | 2.04e-04 | -0.320000 | 1.86e-03 |
| Platelet degranulation | 104 | 1.95e-08 | -0.319000 | 4.67e-07 |
| Syndecan interactions | 19 | 1.65e-02 | -0.318000 | 5.17e-02 |
| Base-Excision Repair, AP Site Formation | 31 | 2.23e-03 | -0.317000 | 1.26e-02 |
| Disorders of developmental biology | 12 | 5.74e-02 | -0.317000 | 1.31e-01 |
| Loss of function of MECP2 in Rett syndrome | 12 | 5.74e-02 | -0.317000 | 1.31e-01 |
| Pervasive developmental disorders | 12 | 5.74e-02 | -0.317000 | 1.31e-01 |
| Nuclear signaling by ERBB4 | 24 | 7.44e-03 | -0.316000 | 2.83e-02 |
| Response to elevated platelet cytosolic Ca2+ | 108 | 1.48e-08 | -0.315000 | 3.68e-07 |
| mRNA Splicing - Minor Pathway | 52 | 9.11e-05 | -0.314000 | 9.79e-04 |
| Incretin synthesis, secretion, and inactivation | 10 | 8.67e-02 | 0.313000 | 1.80e-01 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | 10 | 8.67e-02 | 0.313000 | 1.80e-01 |
| Folding of actin by CCT/TriC | 10 | 8.81e-02 | -0.311000 | 1.82e-01 |
| Infection with Mycobacterium tuberculosis | 26 | 6.04e-03 | -0.311000 | 2.47e-02 |
| Synthesis of IP3 and IP4 in the cytosol | 22 | 1.16e-02 | -0.311000 | 3.95e-02 |
| Classical antibody-mediated complement activation | 69 | 9.04e-06 | 0.309000 | 1.43e-04 |
| Mitochondrial protein import | 64 | 1.98e-05 | -0.308000 | 2.70e-04 |
| Gap junction trafficking and regulation | 16 | 3.27e-02 | -0.308000 | 8.66e-02 |
| RIPK1-mediated regulated necrosis | 16 | 3.31e-02 | 0.308000 | 8.69e-02 |
| Regulated Necrosis | 16 | 3.31e-02 | 0.308000 | 8.69e-02 |
| FGFR2 alternative splicing | 25 | 7.76e-03 | -0.308000 | 2.90e-02 |
| Platelet Aggregation (Plug Formation) | 28 | 4.85e-03 | -0.308000 | 2.13e-02 |
| Translation of structural proteins | 28 | 4.88e-03 | -0.307000 | 2.13e-02 |
| IRAK2 mediated activation of TAK1 complex | 10 | 9.31e-02 | -0.307000 | 1.89e-01 |
| Signaling by NOTCH3 | 43 | 5.09e-04 | -0.306000 | 4.05e-03 |
| Dissolution of Fibrin Clot | 12 | 6.63e-02 | -0.306000 | 1.47e-01 |
| Defective EXT1 causes exostoses 1, TRPS2 and CHDS | 10 | 9.59e-02 | -0.304000 | 1.93e-01 |
| Defective EXT2 causes exostoses 2 | 10 | 9.59e-02 | -0.304000 | 1.93e-01 |
| MicroRNA (miRNA) biogenesis | 24 | 1.00e-02 | -0.304000 | 3.49e-02 |
| Transferrin endocytosis and recycling | 26 | 7.53e-03 | -0.303000 | 2.84e-02 |
| HSF1 activation | 26 | 7.75e-03 | -0.302000 | 2.90e-02 |
| Intrinsic Pathway of Fibrin Clot Formation | 16 | 3.68e-02 | -0.301000 | 9.43e-02 |
| Metabolism of Angiotensinogen to Angiotensins | 11 | 8.43e-02 | -0.301000 | 1.77e-01 |
| Mitochondrial calcium ion transport | 22 | 1.58e-02 | -0.297000 | 5.02e-02 |
| Budding and maturation of HIV virion | 26 | 8.95e-03 | -0.296000 | 3.19e-02 |
| Notch-HLH transcription pathway | 28 | 6.77e-03 | -0.296000 | 2.67e-02 |
| HDR through Single Strand Annealing (SSA) | 37 | 1.86e-03 | 0.296000 | 1.10e-02 |
| Creation of C4 and C2 activators | 71 | 1.67e-05 | 0.295000 | 2.32e-04 |
| Cleavage of the damaged pyrimidine | 29 | 6.01e-03 | -0.295000 | 2.46e-02 |
| Depyrimidination | 29 | 6.01e-03 | -0.295000 | 2.46e-02 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | 29 | 6.01e-03 | -0.295000 | 2.46e-02 |
| PCP/CE pathway | 87 | 2.03e-06 | -0.295000 | 3.91e-05 |
| Elevation of cytosolic Ca2+ levels | 13 | 6.66e-02 | -0.294000 | 1.47e-01 |
| InlB-mediated entry of Listeria monocytogenes into host cell | 12 | 7.85e-02 | -0.293000 | 1.66e-01 |
| Regulation of PTEN gene transcription | 59 | 1.04e-04 | -0.292000 | 1.09e-03 |
| Cell-extracellular matrix interactions | 14 | 5.85e-02 | -0.292000 | 1.33e-01 |
| Initial triggering of complement | 78 | 8.77e-06 | 0.291000 | 1.42e-04 |
| Collagen formation | 64 | 5.69e-05 | -0.291000 | 6.53e-04 |
| TAK1 activates NFkB by phosphorylation and activation of IKKs complex | 27 | 8.94e-03 | -0.291000 | 3.19e-02 |
| Mitochondrial translation elongation | 91 | 1.64e-06 | -0.291000 | 3.29e-05 |
| HDACs deacetylate histones | 47 | 5.70e-04 | -0.290000 | 4.37e-03 |
| Pregnenolone biosynthesis | 10 | 1.13e-01 | -0.289000 | 2.19e-01 |
| Serotonin Neurotransmitter Release Cycle | 14 | 6.12e-02 | -0.289000 | 1.38e-01 |
| Axon guidance | 459 | 2.50e-26 | -0.289000 | 1.42e-24 |
| Repression of WNT target genes | 14 | 6.16e-02 | -0.288000 | 1.39e-01 |
| Signaling by EGFR | 46 | 7.13e-04 | -0.288000 | 5.29e-03 |
| mitochondrial fatty acid beta-oxidation of saturated fatty acids | 11 | 9.81e-02 | -0.288000 | 1.95e-01 |
| Attenuation phase | 23 | 1.68e-02 | -0.288000 | 5.23e-02 |
| TRAF6 mediated IRF7 activation | 15 | 5.44e-02 | 0.287000 | 1.27e-01 |
| Metabolism of carbohydrates | 242 | 2.67e-14 | -0.284000 | 8.29e-13 |
| G-protein mediated events | 44 | 1.12e-03 | -0.284000 | 7.38e-03 |
| Regulation of necroptotic cell death | 14 | 6.59e-02 | 0.284000 | 1.46e-01 |
| RAF-independent MAPK1/3 activation | 21 | 2.47e-02 | -0.283000 | 6.95e-02 |
| Purine catabolism | 16 | 5.08e-02 | -0.282000 | 1.20e-01 |
| Negative regulation of FGFR2 signaling | 23 | 1.95e-02 | -0.281000 | 5.79e-02 |
| Butyrophilin (BTN) family interactions | 10 | 1.24e-01 | 0.281000 | 2.32e-01 |
| MyD88 cascade initiated on plasma membrane | 82 | 1.07e-05 | -0.281000 | 1.58e-04 |
| Toll Like Receptor 10 (TLR10) Cascade | 82 | 1.07e-05 | -0.281000 | 1.58e-04 |
| Toll Like Receptor 5 (TLR5) Cascade | 82 | 1.07e-05 | -0.281000 | 1.58e-04 |
| PLC beta mediated events | 43 | 1.44e-03 | -0.281000 | 9.01e-03 |
| Regulation of KIT signaling | 15 | 6.07e-02 | -0.280000 | 1.37e-01 |
| Nervous system development | 478 | 1.20e-25 | -0.279000 | 6.30e-24 |
| EPH-Ephrin signaling | 80 | 1.70e-05 | -0.278000 | 2.35e-04 |
| Cellular responses to stress | 500 | 2.05e-26 | -0.277000 | 1.27e-24 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | 12 | 9.72e-02 | -0.276000 | 1.94e-01 |
| Nuclear Receptor transcription pathway | 41 | 2.24e-03 | -0.276000 | 1.26e-02 |
| DCC mediated attractive signaling | 13 | 8.52e-02 | -0.276000 | 1.78e-01 |
| Cellular responses to external stimuli | 506 | 2.17e-26 | -0.276000 | 1.29e-24 |
| Diseases associated with glycosaminoglycan metabolism | 27 | 1.33e-02 | -0.275000 | 4.41e-02 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | 92 | 5.34e-06 | -0.274000 | 9.12e-05 |
| Toll Like Receptor 2 (TLR2) Cascade | 92 | 5.34e-06 | -0.274000 | 9.12e-05 |
| Toll Like Receptor TLR1:TLR2 Cascade | 92 | 5.34e-06 | -0.274000 | 9.12e-05 |
| Toll Like Receptor TLR6:TLR2 Cascade | 92 | 5.34e-06 | -0.274000 | 9.12e-05 |
| Termination of O-glycan biosynthesis | 16 | 5.92e-02 | -0.272000 | 1.35e-01 |
| Long-term potentiation | 15 | 6.79e-02 | -0.272000 | 1.49e-01 |
| Prefoldin mediated transfer of substrate to CCT/TriC | 26 | 1.63e-02 | -0.272000 | 5.12e-02 |
| Collagen chain trimerization | 27 | 1.46e-02 | -0.271000 | 4.74e-02 |
| Other interleukin signaling | 18 | 4.67e-02 | -0.271000 | 1.13e-01 |
| CD28 dependent PI3K/Akt signaling | 22 | 2.79e-02 | -0.271000 | 7.72e-02 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | 32 | 8.23e-03 | 0.270000 | 3.03e-02 |
| ERK/MAPK targets | 22 | 2.86e-02 | -0.270000 | 7.84e-02 |
| CD22 mediated BCR regulation | 59 | 3.45e-04 | 0.269000 | 2.83e-03 |
| Negative regulation of FGFR1 signaling | 24 | 2.25e-02 | -0.269000 | 6.54e-02 |
| Aggrephagy | 22 | 2.91e-02 | -0.269000 | 7.92e-02 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | 35 | 6.00e-03 | -0.268000 | 2.46e-02 |
| Plasma lipoprotein assembly, remodeling, and clearance | 54 | 6.55e-04 | -0.268000 | 4.92e-03 |
| GRB2 events in ERBB2 signaling | 11 | 1.24e-01 | -0.268000 | 2.33e-01 |
| Lewis blood group biosynthesis | 13 | 9.72e-02 | -0.266000 | 1.94e-01 |
| Iron uptake and transport | 52 | 9.24e-04 | -0.266000 | 6.31e-03 |
| Neurexins and neuroligins | 38 | 4.64e-03 | -0.265000 | 2.08e-02 |
| Signaling by EGFR in Cancer | 23 | 2.80e-02 | -0.265000 | 7.73e-02 |
| GRB2 events in EGFR signaling | 11 | 1.29e-01 | -0.265000 | 2.40e-01 |
| Signaling by NOTCH1 | 67 | 1.89e-04 | -0.264000 | 1.75e-03 |
| Scavenging of heme from plasma | 71 | 1.34e-04 | 0.262000 | 1.33e-03 |
| DNA Damage Recognition in GG-NER | 38 | 5.22e-03 | -0.262000 | 2.24e-02 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | 25 | 2.35e-02 | -0.262000 | 6.74e-02 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | 88 | 2.29e-05 | -0.261000 | 3.01e-04 |
| N-glycan antennae elongation in the medial/trans-Golgi | 21 | 3.86e-02 | -0.261000 | 9.75e-02 |
| CRMPs in Sema3A signaling | 14 | 9.15e-02 | -0.260000 | 1.87e-01 |
| Processing of SMDT1 | 15 | 8.09e-02 | -0.260000 | 1.70e-01 |
| Regulation of TP53 Activity through Acetylation | 29 | 1.53e-02 | -0.260000 | 4.91e-02 |
| Platelet activation, signaling and aggregation | 219 | 3.25e-11 | -0.260000 | 9.04e-10 |
| Vitamin D (calciferol) metabolism | 10 | 1.55e-01 | -0.259000 | 2.77e-01 |
| Interleukin-7 signaling | 21 | 4.07e-02 | -0.258000 | 1.02e-01 |
| Mitochondrial translation initiation | 91 | 2.10e-05 | -0.258000 | 2.81e-04 |
| Cyclin A/B1/B2 associated events during G2/M transition | 24 | 2.97e-02 | 0.256000 | 8.03e-02 |
| Mitochondrial translation termination | 91 | 2.38e-05 | -0.256000 | 3.09e-04 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | 15 | 8.60e-02 | -0.256000 | 1.79e-01 |
| FGFR2 mutant receptor activation | 22 | 3.78e-02 | -0.256000 | 9.62e-02 |
| NOTCH1 Intracellular Domain Regulates Transcription | 45 | 3.15e-03 | -0.254000 | 1.62e-02 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | 42 | 4.34e-03 | -0.254000 | 1.99e-02 |
| HIV Transcription Elongation | 42 | 4.34e-03 | -0.254000 | 1.99e-02 |
| Tat-mediated elongation of the HIV-1 transcript | 42 | 4.34e-03 | -0.254000 | 1.99e-02 |
| Signaling by NOTCH2 | 30 | 1.59e-02 | -0.254000 | 5.04e-02 |
| Keratan sulfate/keratin metabolism | 27 | 2.26e-02 | -0.253000 | 6.54e-02 |
| Carnitine metabolism | 10 | 1.66e-01 | -0.253000 | 2.92e-01 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | 54 | 1.33e-03 | -0.252000 | 8.43e-03 |
| Thrombin signalling through proteinase activated receptors (PARs) | 27 | 2.33e-02 | -0.252000 | 6.68e-02 |
| Erythrocytes take up carbon dioxide and release oxygen | 11 | 1.48e-01 | -0.252000 | 2.66e-01 |
| O2/CO2 exchange in erythrocytes | 11 | 1.48e-01 | -0.252000 | 2.66e-01 |
| Resolution of D-Loop Structures | 33 | 1.24e-02 | 0.252000 | 4.13e-02 |
| Endosomal/Vacuolar pathway | 12 | 1.32e-01 | -0.251000 | 2.44e-01 |
| E2F mediated regulation of DNA replication | 22 | 4.15e-02 | 0.251000 | 1.03e-01 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | 29 | 1.97e-02 | -0.250000 | 5.84e-02 |
| Gamma carboxylation, hypusine formation and arylsulfatase activation | 34 | 1.17e-02 | -0.250000 | 3.96e-02 |
| Degradation of cysteine and homocysteine | 13 | 1.19e-01 | -0.250000 | 2.27e-01 |
| Antiviral mechanism by IFN-stimulated genes | 80 | 1.17e-04 | 0.249000 | 1.20e-03 |
| MyD88 dependent cascade initiated on endosome | 89 | 5.10e-05 | -0.248000 | 5.95e-04 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | 89 | 5.10e-05 | -0.248000 | 5.95e-04 |
| TGF-beta receptor signaling activates SMADs | 32 | 1.54e-02 | -0.248000 | 4.91e-02 |
| Synaptic adhesion-like molecules | 16 | 8.69e-02 | -0.247000 | 1.80e-01 |
| ADORA2B mediated anti-inflammatory cytokines production | 74 | 2.38e-04 | -0.247000 | 2.08e-03 |
| Glucagon signaling in metabolic regulation | 27 | 2.63e-02 | -0.247000 | 7.30e-02 |
| Recycling pathway of L1 | 26 | 2.97e-02 | -0.246000 | 8.03e-02 |
| PI3K/AKT Signaling in Cancer | 81 | 1.27e-04 | -0.246000 | 1.28e-03 |
| mTORC1-mediated signalling | 23 | 4.11e-02 | -0.246000 | 1.02e-01 |
| Synthesis of PE | 12 | 1.41e-01 | 0.245000 | 2.57e-01 |
| G alpha (z) signalling events | 36 | 1.09e-02 | -0.245000 | 3.76e-02 |
| Aquaporin-mediated transport | 38 | 9.23e-03 | -0.244000 | 3.25e-02 |
| Platelet Adhesion to exposed collagen | 13 | 1.29e-01 | -0.243000 | 2.41e-01 |
| Interleukin-1 signaling | 98 | 3.24e-05 | -0.243000 | 4.06e-04 |
| NS1 Mediated Effects on Host Pathways | 40 | 8.13e-03 | 0.242000 | 3.00e-02 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | 29 | 2.46e-02 | -0.241000 | 6.94e-02 |
| Mitochondrial translation | 97 | 4.12e-05 | -0.241000 | 5.02e-04 |
| IRE1alpha activates chaperones | 49 | 3.59e-03 | -0.240000 | 1.78e-02 |
| DAG and IP3 signaling | 33 | 1.71e-02 | -0.240000 | 5.29e-02 |
| Early Phase of HIV Life Cycle | 14 | 1.22e-01 | -0.239000 | 2.29e-01 |
| Metabolism of amino acids and derivatives | 326 | 1.24e-13 | -0.239000 | 3.67e-12 |
| Maturation of nucleoprotein | 10 | 1.91e-01 | 0.239000 | 3.24e-01 |
| TRAF6 mediated NF-kB activation | 23 | 4.77e-02 | -0.238000 | 1.15e-01 |
| UCH proteinases | 87 | 1.24e-04 | -0.238000 | 1.26e-03 |
| Gastrin-CREB signalling pathway via PKC and MAPK | 14 | 1.23e-01 | -0.238000 | 2.32e-01 |
| Signaling by NOTCH | 183 | 3.36e-08 | -0.237000 | 7.78e-07 |
| RHO GTPases Activate WASPs and WAVEs | 35 | 1.58e-02 | -0.236000 | 5.02e-02 |
| Activation of SMO | 13 | 1.41e-01 | -0.236000 | 2.57e-01 |
| Formation of the Early Elongation Complex | 33 | 1.93e-02 | -0.235000 | 5.75e-02 |
| Formation of the HIV-1 Early Elongation Complex | 33 | 1.93e-02 | -0.235000 | 5.75e-02 |
| Vpu mediated degradation of CD4 | 51 | 3.76e-03 | -0.235000 | 1.83e-02 |
| FCGR activation | 76 | 4.16e-04 | 0.234000 | 3.38e-03 |
| Oxidative Stress Induced Senescence | 79 | 3.23e-04 | -0.234000 | 2.70e-03 |
| Metabolism of fat-soluble vitamins | 28 | 3.21e-02 | -0.234000 | 8.55e-02 |
| SARS-CoV-1 Infection | 47 | 5.56e-03 | -0.234000 | 2.35e-02 |
| Nicotinamide salvaging | 15 | 1.17e-01 | 0.234000 | 2.25e-01 |
| Base Excision Repair | 58 | 2.10e-03 | -0.233000 | 1.22e-02 |
| Glycogen breakdown (glycogenolysis) | 13 | 1.45e-01 | -0.233000 | 2.63e-01 |
| PECAM1 interactions | 12 | 1.63e-01 | -0.233000 | 2.87e-01 |
| Interleukin-17 signaling | 68 | 9.22e-04 | -0.232000 | 6.31e-03 |
| XBP1(S) activates chaperone genes | 47 | 5.92e-03 | -0.232000 | 2.46e-02 |
| Listeria monocytogenes entry into host cells | 17 | 9.77e-02 | -0.232000 | 1.94e-01 |
| Synthesis of PIPs at the early endosome membrane | 16 | 1.09e-01 | 0.232000 | 2.13e-01 |
| Formation of the beta-catenin:TCF transactivating complex | 46 | 6.64e-03 | -0.231000 | 2.64e-02 |
| Cell-Cell communication | 88 | 1.82e-04 | -0.231000 | 1.71e-03 |
| ABC transporter disorders | 71 | 8.19e-04 | -0.230000 | 5.73e-03 |
| p75 NTR receptor-mediated signalling | 88 | 1.96e-04 | -0.230000 | 1.80e-03 |
| Signaling by ERBB2 | 44 | 8.52e-03 | -0.229000 | 3.13e-02 |
| Activation of the AP-1 family of transcription factors | 10 | 2.10e-01 | -0.229000 | 3.45e-01 |
| Amino acids regulate mTORC1 | 50 | 5.07e-03 | -0.229000 | 2.20e-02 |
| MAP2K and MAPK activation | 34 | 2.08e-02 | -0.229000 | 6.11e-02 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | 20 | 7.66e-02 | -0.229000 | 1.63e-01 |
| Trafficking of AMPA receptors | 20 | 7.66e-02 | -0.229000 | 1.63e-01 |
| Plasma lipoprotein assembly | 11 | 1.90e-01 | -0.228000 | 3.23e-01 |
| Degradation of DVL | 55 | 3.43e-03 | -0.228000 | 1.73e-02 |
| Presynaptic function of Kainate receptors | 18 | 9.43e-02 | -0.228000 | 1.91e-01 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | 11 | 1.92e-01 | -0.227000 | 3.25e-01 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | 25 | 5.08e-02 | -0.226000 | 1.20e-01 |
| Ubiquitin-dependent degradation of Cyclin D | 51 | 5.34e-03 | -0.225000 | 2.28e-02 |
| The NLRP3 inflammasome | 15 | 1.31e-01 | -0.225000 | 2.43e-01 |
| Toll Like Receptor 9 (TLR9) Cascade | 93 | 1.75e-04 | -0.225000 | 1.68e-03 |
| Regulation of innate immune responses to cytosolic DNA | 14 | 1.45e-01 | -0.225000 | 2.62e-01 |
| Citric acid cycle (TCA cycle) | 22 | 6.80e-02 | -0.225000 | 1.49e-01 |
| Asymmetric localization of PCP proteins | 61 | 2.50e-03 | -0.224000 | 1.38e-02 |
| Developmental Biology | 738 | 3.98e-25 | -0.224000 | 2.01e-23 |
| Negative regulation of NOTCH4 signaling | 54 | 4.50e-03 | -0.223000 | 2.04e-02 |
| Regulation of Complement cascade | 94 | 1.84e-04 | 0.223000 | 1.72e-03 |
| Activation of kainate receptors upon glutamate binding | 26 | 4.88e-02 | -0.223000 | 1.17e-01 |
| SHC1 events in EGFR signaling | 12 | 1.81e-01 | -0.223000 | 3.11e-01 |
| PRC2 methylates histones and DNA | 29 | 3.76e-02 | -0.223000 | 9.61e-02 |
| Nucleotide salvage | 21 | 7.69e-02 | -0.223000 | 1.63e-01 |
| p130Cas linkage to MAPK signaling for integrins | 11 | 2.02e-01 | -0.222000 | 3.35e-01 |
| MAP kinase activation | 63 | 2.28e-03 | -0.222000 | 1.28e-02 |
| Chemokine receptors bind chemokines | 40 | 1.51e-02 | -0.222000 | 4.90e-02 |
| Dopamine Neurotransmitter Release Cycle | 19 | 9.43e-02 | -0.222000 | 1.91e-01 |
| Signaling by Activin | 10 | 2.25e-01 | -0.221000 | 3.64e-01 |
| Dectin-1 mediated noncanonical NF-kB signaling | 60 | 3.03e-03 | -0.221000 | 1.58e-02 |
| GLI3 is processed to GLI3R by the proteasome | 58 | 3.58e-03 | -0.221000 | 1.78e-02 |
| Extracellular matrix organization | 220 | 1.67e-08 | -0.221000 | 4.07e-07 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | 30 | 3.66e-02 | -0.220000 | 9.40e-02 |
| Regulation of RUNX3 expression and activity | 55 | 4.67e-03 | -0.220000 | 2.08e-02 |
| Toll Like Receptor 4 (TLR4) Cascade | 121 | 2.96e-05 | -0.220000 | 3.77e-04 |
| Autodegradation of the E3 ubiquitin ligase COP1 | 50 | 7.33e-03 | -0.219000 | 2.80e-02 |
| Signaling by FGFR2 | 60 | 3.37e-03 | -0.219000 | 1.70e-02 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | 49 | 8.12e-03 | -0.219000 | 3.00e-02 |
| Cargo recognition for clathrin-mediated endocytosis | 90 | 3.41e-04 | -0.218000 | 2.83e-03 |
| Protein-protein interactions at synapses | 59 | 3.79e-03 | -0.218000 | 1.83e-02 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | 15 | 1.44e-01 | -0.218000 | 2.61e-01 |
| Vasopressin regulates renal water homeostasis via Aquaporins | 34 | 2.82e-02 | -0.217000 | 7.77e-02 |
| Defective CFTR causes cystic fibrosis | 60 | 3.60e-03 | -0.217000 | 1.78e-02 |
| Selective autophagy | 59 | 3.90e-03 | -0.217000 | 1.87e-02 |
| Signaling by Insulin receptor | 59 | 4.04e-03 | -0.216000 | 1.90e-02 |
| Regulation of signaling by CBL | 18 | 1.13e-01 | -0.216000 | 2.19e-01 |
| SLBP independent Processing of Histone Pre-mRNAs | 10 | 2.37e-01 | -0.216000 | 3.75e-01 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | 16 | 1.35e-01 | -0.216000 | 2.50e-01 |
| Degradation of the extracellular matrix | 81 | 8.12e-04 | -0.215000 | 5.71e-03 |
| Telomere Maintenance | 80 | 8.84e-04 | -0.215000 | 6.10e-03 |
| Signaling by high-kinase activity BRAF mutants | 31 | 3.84e-02 | -0.215000 | 9.73e-02 |
| Cellular response to hypoxia | 72 | 1.64e-03 | -0.215000 | 9.97e-03 |
| GPVI-mediated activation cascade | 31 | 3.94e-02 | -0.214000 | 9.87e-02 |
| Calnexin/calreticulin cycle | 26 | 5.93e-02 | -0.214000 | 1.35e-01 |
| Autophagy | 125 | 3.68e-05 | -0.214000 | 4.52e-04 |
| Sema3A PAK dependent Axon repulsion | 16 | 1.40e-01 | -0.213000 | 2.55e-01 |
| NIK-->noncanonical NF-kB signaling | 58 | 5.12e-03 | -0.212000 | 2.20e-02 |
| Protein localization | 157 | 4.37e-06 | -0.212000 | 7.85e-05 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | 54 | 7.00e-03 | -0.212000 | 2.71e-02 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | 54 | 7.00e-03 | -0.212000 | 2.71e-02 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | 54 | 7.00e-03 | -0.212000 | 2.71e-02 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | 54 | 7.00e-03 | -0.212000 | 2.71e-02 |
| Signaling by NOTCH1 in Cancer | 54 | 7.00e-03 | -0.212000 | 2.71e-02 |
| Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | 51 | 8.77e-03 | -0.212000 | 3.17e-02 |
| p53-Independent DNA Damage Response | 51 | 8.77e-03 | -0.212000 | 3.17e-02 |
| p53-Independent G1/S DNA damage checkpoint | 51 | 8.77e-03 | -0.212000 | 3.17e-02 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | 12 | 2.03e-01 | -0.212000 | 3.37e-01 |
| Vif-mediated degradation of APOBEC3G | 53 | 7.64e-03 | -0.212000 | 2.87e-02 |
| CD28 co-stimulation | 33 | 3.57e-02 | -0.211000 | 9.21e-02 |
| Activation of BAD and translocation to mitochondria | 15 | 1.57e-01 | -0.211000 | 2.79e-01 |
| Establishment of Sister Chromatid Cohesion | 11 | 2.26e-01 | 0.211000 | 3.64e-01 |
| RNA Polymerase III Chain Elongation | 18 | 1.21e-01 | -0.211000 | 2.29e-01 |
| Polo-like kinase mediated events | 15 | 1.58e-01 | 0.211000 | 2.80e-01 |
| Hh mutants abrogate ligand secretion | 55 | 6.94e-03 | -0.210000 | 2.71e-02 |
| Signaling by VEGF | 97 | 3.42e-04 | -0.210000 | 2.83e-03 |
| Caspase-mediated cleavage of cytoskeletal proteins | 12 | 2.07e-01 | -0.210000 | 3.41e-01 |
| Hh mutants that don't undergo autocatalytic processing are degraded by ERAD | 54 | 7.53e-03 | -0.210000 | 2.84e-02 |
| Formation of HIV elongation complex in the absence of HIV Tat | 44 | 1.58e-02 | -0.210000 | 5.02e-02 |
| Nuclear Events (kinase and transcription factor activation) | 55 | 7.14e-03 | -0.210000 | 2.75e-02 |
| Signaling by NOTCH4 | 79 | 1.29e-03 | -0.209000 | 8.22e-03 |
| SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | 11 | 2.30e-01 | -0.209000 | 3.69e-01 |
| Interaction between L1 and Ankyrins | 22 | 8.96e-02 | 0.209000 | 1.85e-01 |
| Semaphorin interactions | 57 | 6.37e-03 | -0.209000 | 2.56e-02 |
| Activation of NF-kappaB in B cells | 66 | 3.35e-03 | -0.209000 | 1.70e-02 |
| Activation of BH3-only proteins | 30 | 4.81e-02 | -0.209000 | 1.15e-01 |
| Transport of Ribonucleoproteins into the Host Nucleus | 32 | 4.12e-02 | 0.208000 | 1.03e-01 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | 17 | 1.37e-01 | -0.208000 | 2.51e-01 |
| Cellular Senescence | 144 | 1.60e-05 | -0.208000 | 2.28e-04 |
| Degradation of GLI2 by the proteasome | 57 | 6.60e-03 | -0.208000 | 2.63e-02 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | 14 | 1.78e-01 | -0.208000 | 3.08e-01 |
| Formation of tubulin folding intermediates by CCT/TriC | 22 | 9.20e-02 | -0.208000 | 1.87e-01 |
| Cell junction organization | 59 | 5.96e-03 | -0.207000 | 2.46e-02 |
| IRAK1 recruits IKK complex | 10 | 2.57e-01 | -0.207000 | 3.98e-01 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | 10 | 2.57e-01 | -0.207000 | 3.98e-01 |
| Interleukin-1 family signaling | 125 | 6.57e-05 | -0.207000 | 7.47e-04 |
| Regulation of TLR by endogenous ligand | 11 | 2.35e-01 | -0.207000 | 3.73e-01 |
| Keratan sulfate biosynthesis | 22 | 9.43e-02 | -0.206000 | 1.91e-01 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | 83 | 1.18e-03 | -0.206000 | 7.75e-03 |
| G beta:gamma signalling through PLC beta | 17 | 1.42e-01 | -0.206000 | 2.59e-01 |
| Constitutive Signaling by Aberrant PI3K in Cancer | 54 | 9.04e-03 | -0.205000 | 3.21e-02 |
| MAPK targets/ Nuclear events mediated by MAP kinases | 31 | 4.79e-02 | -0.205000 | 1.15e-01 |
| Regulation of ornithine decarboxylase (ODC) | 50 | 1.23e-02 | -0.205000 | 4.13e-02 |
| VEGFA-VEGFR2 Pathway | 90 | 7.92e-04 | -0.205000 | 5.60e-03 |
| Signaling by Receptor Tyrosine Kinases | 413 | 1.02e-12 | -0.204000 | 2.95e-11 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | 53 | 1.01e-02 | -0.204000 | 3.52e-02 |
| Intracellular signaling by second messengers | 273 | 6.72e-09 | -0.204000 | 1.77e-07 |
| Association of TriC/CCT with target proteins during biosynthesis | 37 | 3.24e-02 | -0.203000 | 8.59e-02 |
| Inositol phosphate metabolism | 43 | 2.11e-02 | -0.203000 | 6.16e-02 |
| SUMOylation of intracellular receptors | 27 | 6.77e-02 | -0.203000 | 1.49e-01 |
| Macroautophagy | 111 | 2.19e-04 | -0.203000 | 1.94e-03 |
| Oncogene Induced Senescence | 33 | 4.39e-02 | -0.203000 | 1.07e-01 |
| Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane | 11 | 2.45e-01 | -0.203000 | 3.84e-01 |
| Hedgehog 'off' state | 93 | 7.48e-04 | -0.202000 | 5.40e-03 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | 11 | 2.47e-01 | 0.201000 | 3.87e-01 |
| mRNA Splicing - Major Pathway | 179 | 3.46e-06 | -0.201000 | 6.30e-05 |
| Uptake and actions of bacterial toxins | 27 | 7.05e-02 | -0.201000 | 1.53e-01 |
| Condensation of Prophase Chromosomes | 29 | 6.12e-02 | -0.201000 | 1.38e-01 |
| Negative regulation of the PI3K/AKT network | 87 | 1.22e-03 | -0.201000 | 7.87e-03 |
| Effects of PIP2 hydrolysis | 24 | 8.91e-02 | -0.200000 | 1.84e-01 |
| Positive epigenetic regulation of rRNA expression | 62 | 6.39e-03 | -0.200000 | 2.57e-02 |
| Retinoid metabolism and transport | 24 | 8.96e-02 | -0.200000 | 1.85e-01 |
| Role of LAT2/NTAL/LAB on calcium mobilization | 74 | 2.93e-03 | 0.200000 | 1.54e-02 |
| Complement cascade | 98 | 6.25e-04 | 0.200000 | 4.77e-03 |
| Transcriptional Regulation by MECP2 | 47 | 1.78e-02 | -0.200000 | 5.45e-02 |
| Degradation of beta-catenin by the destruction complex | 84 | 1.56e-03 | -0.200000 | 9.62e-03 |
| Nephrin family interactions | 18 | 1.43e-01 | -0.200000 | 2.59e-01 |
| CD28 dependent Vav1 pathway | 12 | 2.32e-01 | -0.199000 | 3.70e-01 |
| Signaling by Non-Receptor Tyrosine Kinases | 48 | 1.69e-02 | -0.199000 | 5.24e-02 |
| Signaling by PTK6 | 48 | 1.69e-02 | -0.199000 | 5.24e-02 |
| Degradation of AXIN | 54 | 1.14e-02 | -0.199000 | 3.89e-02 |
| B-WICH complex positively regulates rRNA expression | 47 | 1.83e-02 | -0.199000 | 5.56e-02 |
| NR1H2 and NR1H3-mediated signaling | 40 | 2.95e-02 | -0.199000 | 8.02e-02 |
| Infectious disease | 725 | 7.61e-20 | -0.199000 | 2.89e-18 |
| ISG15 antiviral mechanism | 72 | 3.58e-03 | 0.198000 | 1.78e-02 |
| Cell death signalling via NRAGE, NRIF and NADE | 69 | 4.36e-03 | -0.198000 | 1.99e-02 |
| SUMOylation of ubiquitinylation proteins | 39 | 3.20e-02 | 0.198000 | 8.52e-02 |
| MyD88-independent TLR4 cascade | 96 | 7.87e-04 | -0.198000 | 5.60e-03 |
| TRIF(TICAM1)-mediated TLR4 signaling | 96 | 7.87e-04 | -0.198000 | 5.60e-03 |
| Transport of the SLBP independent Mature mRNA | 35 | 4.26e-02 | 0.198000 | 1.05e-01 |
| Signal transduction by L1 | 20 | 1.26e-01 | -0.198000 | 2.35e-01 |
| DAP12 interactions | 39 | 3.26e-02 | -0.198000 | 8.64e-02 |
| NEP/NS2 Interacts with the Cellular Export Machinery | 32 | 5.31e-02 | 0.198000 | 1.24e-01 |
| Pre-NOTCH Expression and Processing | 65 | 5.88e-03 | -0.198000 | 2.46e-02 |
| trans-Golgi Network Vesicle Budding | 69 | 4.60e-03 | -0.197000 | 2.07e-02 |
| Signaling by NTRKs | 117 | 2.29e-04 | -0.197000 | 2.02e-03 |
| Opioid Signalling | 75 | 3.19e-03 | -0.197000 | 1.63e-02 |
| Regulation of FOXO transcriptional activity by acetylation | 10 | 2.81e-01 | -0.197000 | 4.26e-01 |
| IRF3-mediated induction of type I IFN | 12 | 2.38e-01 | -0.197000 | 3.75e-01 |
| Toll Like Receptor 3 (TLR3) Cascade | 92 | 1.10e-03 | -0.197000 | 7.31e-03 |
| Downregulation of TGF-beta receptor signaling | 26 | 8.25e-02 | -0.197000 | 1.73e-01 |
| Beta-catenin independent WNT signaling | 137 | 7.28e-05 | -0.196000 | 8.15e-04 |
| Glucagon-type ligand receptors | 20 | 1.30e-01 | -0.196000 | 2.41e-01 |
| TCF dependent signaling in response to WNT | 167 | 1.27e-05 | -0.196000 | 1.86e-04 |
| Signaling by NTRK1 (TRKA) | 102 | 6.44e-04 | -0.195000 | 4.86e-03 |
| PIP3 activates AKT signaling | 241 | 1.72e-07 | -0.195000 | 3.84e-06 |
| Surfactant metabolism | 22 | 1.13e-01 | -0.195000 | 2.19e-01 |
| Autodegradation of Cdh1 by Cdh1:APC/C | 64 | 6.88e-03 | -0.195000 | 2.71e-02 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | 13 | 2.23e-01 | -0.195000 | 3.61e-01 |
| Innate Immune System | 969 | 7.13e-25 | -0.195000 | 3.47e-23 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | 65 | 6.52e-03 | -0.195000 | 2.61e-02 |
| SARS-CoV Infections | 83 | 2.25e-03 | -0.194000 | 1.27e-02 |
| Clathrin-mediated endocytosis | 127 | 1.64e-04 | -0.194000 | 1.60e-03 |
| SIRT1 negatively regulates rRNA expression | 24 | 1.01e-01 | -0.194000 | 1.99e-01 |
| G beta:gamma signalling through PI3Kgamma | 22 | 1.17e-01 | -0.193000 | 2.25e-01 |
| Assembly of collagen fibrils and other multimeric structures | 42 | 3.13e-02 | -0.192000 | 8.40e-02 |
| Resolution of Sister Chromatid Cohesion | 104 | 7.18e-04 | 0.192000 | 5.30e-03 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | 80 | 3.07e-03 | -0.191000 | 1.59e-02 |
| Toll-like Receptor Cascades | 143 | 8.12e-05 | -0.191000 | 8.80e-04 |
| Estrogen-dependent gene expression | 99 | 1.03e-03 | -0.191000 | 6.89e-03 |
| Integrin signaling | 22 | 1.22e-01 | -0.191000 | 2.29e-01 |
| Activation of ATR in response to replication stress | 36 | 4.79e-02 | 0.191000 | 1.15e-01 |
| Hedgehog 'on' state | 76 | 4.14e-03 | -0.190000 | 1.94e-02 |
| Formation of TC-NER Pre-Incision Complex | 53 | 1.66e-02 | -0.190000 | 5.20e-02 |
| Interferon Signaling | 177 | 1.28e-05 | 0.190000 | 1.86e-04 |
| PTEN Regulation | 139 | 1.10e-04 | -0.190000 | 1.14e-03 |
| Deactivation of the beta-catenin transactivating complex | 36 | 4.88e-02 | -0.190000 | 1.17e-01 |
| Transcriptional regulation of granulopoiesis | 46 | 2.60e-02 | -0.190000 | 7.26e-02 |
| CLEC7A (Dectin-1) signaling | 98 | 1.19e-03 | -0.189000 | 7.76e-03 |
| Integration of energy metabolism | 86 | 2.44e-03 | -0.189000 | 1.35e-02 |
| Heme degradation | 10 | 3.01e-01 | -0.189000 | 4.51e-01 |
| Transport of the SLBP Dependant Mature mRNA | 36 | 5.02e-02 | 0.189000 | 1.20e-01 |
| RAS processing | 19 | 1.55e-01 | -0.189000 | 2.76e-01 |
| SCF-beta-TrCP mediated degradation of Emi1 | 54 | 1.71e-02 | -0.188000 | 5.28e-02 |
| Signaling by Nuclear Receptors | 219 | 1.78e-06 | -0.187000 | 3.51e-05 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | 31 | 7.15e-02 | 0.187000 | 1.54e-01 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | 31 | 7.15e-02 | 0.187000 | 1.54e-01 |
| SHC1 events in ERBB2 signaling | 17 | 1.83e-01 | -0.187000 | 3.13e-01 |
| FOXO-mediated transcription of cell cycle genes | 15 | 2.11e-01 | -0.186000 | 3.47e-01 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | 91 | 2.19e-03 | 0.186000 | 1.25e-02 |
| Amplification of signal from the kinetochores | 91 | 2.19e-03 | 0.186000 | 1.25e-02 |
| Elastic fibre formation | 32 | 6.94e-02 | -0.185000 | 1.51e-01 |
| Signaling by RAF1 mutants | 34 | 6.22e-02 | -0.185000 | 1.40e-01 |
| Hedgehog ligand biogenesis | 59 | 1.42e-02 | -0.185000 | 4.62e-02 |
| Metabolism of amine-derived hormones | 10 | 3.12e-01 | 0.185000 | 4.61e-01 |
| ESR-mediated signaling | 161 | 5.38e-05 | -0.184000 | 6.23e-04 |
| MECP2 regulates neuronal receptors and channels | 13 | 2.50e-01 | -0.184000 | 3.90e-01 |
| Signaling by Interleukins | 388 | 4.98e-10 | -0.184000 | 1.36e-08 |
| Protein folding | 90 | 2.68e-03 | -0.183000 | 1.46e-02 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | 38 | 5.10e-02 | -0.183000 | 1.20e-01 |
| Signaling by RAS mutants | 38 | 5.10e-02 | -0.183000 | 1.20e-01 |
| Signaling by moderate kinase activity BRAF mutants | 38 | 5.10e-02 | -0.183000 | 1.20e-01 |
| Signaling downstream of RAS mutants | 38 | 5.10e-02 | -0.183000 | 1.20e-01 |
| Signaling by FGFR4 | 31 | 7.80e-02 | -0.183000 | 1.65e-01 |
| NOTCH3 Intracellular Domain Regulates Transcription | 21 | 1.47e-01 | -0.183000 | 2.65e-01 |
| Assembly and cell surface presentation of NMDA receptors | 19 | 1.68e-01 | -0.183000 | 2.94e-01 |
| ER-Phagosome pathway | 83 | 4.03e-03 | -0.183000 | 1.90e-02 |
| mRNA Splicing | 187 | 1.66e-05 | -0.183000 | 2.32e-04 |
| Regulation of Apoptosis | 52 | 2.28e-02 | -0.183000 | 6.57e-02 |
| G alpha (q) signalling events | 134 | 2.64e-04 | -0.182000 | 2.25e-03 |
| NRAGE signals death through JNK | 52 | 2.30e-02 | -0.182000 | 6.60e-02 |
| Interconversion of nucleotide di- and triphosphates | 27 | 1.02e-01 | -0.182000 | 2.00e-01 |
| Degradation of GLI1 by the proteasome | 58 | 1.66e-02 | -0.182000 | 5.20e-02 |
| Diseases associated with the TLR signaling cascade | 23 | 1.33e-01 | -0.181000 | 2.45e-01 |
| Diseases of Immune System | 23 | 1.33e-01 | -0.181000 | 2.45e-01 |
| Metabolism | 1771 | 8.44e-37 | -0.181000 | 1.65e-34 |
| HATs acetylate histones | 93 | 2.57e-03 | -0.181000 | 1.41e-02 |
| SUMOylation of transcription cofactors | 44 | 3.80e-02 | -0.181000 | 9.64e-02 |
| Keratinization | 34 | 6.83e-02 | -0.181000 | 1.49e-01 |
| Integrin cell surface interactions | 52 | 2.43e-02 | -0.181000 | 6.89e-02 |
| RNA Polymerase I Promoter Clearance | 66 | 1.13e-02 | -0.180000 | 3.89e-02 |
| RNA Polymerase I Transcription | 66 | 1.13e-02 | -0.180000 | 3.89e-02 |
| Sema4D induced cell migration and growth-cone collapse | 19 | 1.74e-01 | -0.180000 | 3.02e-01 |
| Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon | 17 | 1.98e-01 | -0.180000 | 3.31e-01 |
| Chaperonin-mediated protein folding | 84 | 4.32e-03 | -0.180000 | 1.99e-02 |
| Metabolism of RNA | 688 | 8.35e-16 | -0.180000 | 2.92e-14 |
| Signaling by Hedgehog | 121 | 6.39e-04 | -0.180000 | 4.85e-03 |
| Interleukin-15 signaling | 14 | 2.45e-01 | -0.180000 | 3.84e-01 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | 64 | 1.30e-02 | -0.179000 | 4.31e-02 |
| Role of phospholipids in phagocytosis | 88 | 3.71e-03 | 0.179000 | 1.81e-02 |
| Binding and Uptake of Ligands by Scavenger Receptors | 92 | 3.16e-03 | 0.178000 | 1.62e-02 |
| Metabolism of polyamines | 58 | 1.92e-02 | -0.178000 | 5.75e-02 |
| Post-chaperonin tubulin folding pathway | 19 | 1.80e-01 | -0.178000 | 3.10e-01 |
| Disease | 1302 | 4.54e-27 | -0.177000 | 3.26e-25 |
| FOXO-mediated transcription | 59 | 1.87e-02 | -0.177000 | 5.65e-02 |
| FCERI mediated Ca+2 mobilization | 89 | 3.95e-03 | 0.177000 | 1.88e-02 |
| Signaling by WNT | 255 | 1.23e-06 | -0.176000 | 2.50e-05 |
| Metabolism of nucleotides | 86 | 4.71e-03 | -0.176000 | 2.08e-02 |
| Signaling by ERBB4 | 44 | 4.32e-02 | -0.176000 | 1.07e-01 |
| Ion homeostasis | 41 | 5.11e-02 | -0.176000 | 1.20e-01 |
| Rab regulation of trafficking | 120 | 8.69e-04 | -0.176000 | 6.02e-03 |
| Host Interactions of HIV factors | 130 | 5.41e-04 | -0.176000 | 4.24e-03 |
| Pre-NOTCH Transcription and Translation | 49 | 3.37e-02 | -0.175000 | 8.79e-02 |
| CASP8 activity is inhibited | 11 | 3.16e-01 | 0.175000 | 4.64e-01 |
| Dimerization of procaspase-8 | 11 | 3.16e-01 | 0.175000 | 4.64e-01 |
| Regulation by c-FLIP | 11 | 3.16e-01 | 0.175000 | 4.64e-01 |
| Beta-catenin phosphorylation cascade | 17 | 2.13e-01 | -0.174000 | 3.50e-01 |
| MET activates RAP1 and RAC1 | 10 | 3.40e-01 | 0.174000 | 4.89e-01 |
| PI3K Cascade | 30 | 9.90e-02 | -0.174000 | 1.96e-01 |
| RHO GTPases activate PKNs | 47 | 3.93e-02 | -0.174000 | 9.87e-02 |
| Chromatin modifying enzymes | 218 | 1.01e-05 | -0.173000 | 1.55e-04 |
| Chromatin organization | 218 | 1.01e-05 | -0.173000 | 1.55e-04 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | 40 | 5.79e-02 | -0.173000 | 1.32e-01 |
| Antigen processing-Cross presentation | 98 | 3.07e-03 | -0.173000 | 1.59e-02 |
| Post-translational protein phosphorylation | 69 | 1.29e-02 | -0.173000 | 4.30e-02 |
| Signaling by FGFR | 69 | 1.30e-02 | -0.173000 | 4.31e-02 |
| FLT3 Signaling | 245 | 3.11e-06 | -0.173000 | 5.90e-05 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | 79 | 7.88e-03 | -0.173000 | 2.93e-02 |
| Class B/2 (Secretin family receptors) | 57 | 2.40e-02 | -0.173000 | 6.85e-02 |
| RNA Pol II CTD phosphorylation and interaction with CE | 27 | 1.21e-01 | -0.172000 | 2.29e-01 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | 27 | 1.21e-01 | -0.172000 | 2.29e-01 |
| Signaling by TGF-beta Receptor Complex | 72 | 1.16e-02 | -0.172000 | 3.95e-02 |
| DARPP-32 events | 22 | 1.63e-01 | -0.172000 | 2.87e-01 |
| Signaling by TGFB family members | 91 | 4.66e-03 | -0.172000 | 2.08e-02 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | 36 | 7.49e-02 | -0.172000 | 1.60e-01 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | 53 | 3.08e-02 | -0.171000 | 8.28e-02 |
| RAF/MAP kinase cascade | 231 | 7.24e-06 | -0.171000 | 1.22e-04 |
| RIP-mediated NFkB activation via ZBP1 | 17 | 2.21e-01 | -0.171000 | 3.59e-01 |
| Downstream TCR signaling | 101 | 2.94e-03 | -0.171000 | 1.54e-02 |
| Sema4D in semaphorin signaling | 22 | 1.65e-01 | -0.171000 | 2.91e-01 |
| Sialic acid metabolism | 28 | 1.17e-01 | -0.171000 | 2.25e-01 |
| Adherens junctions interactions | 17 | 2.24e-01 | -0.170000 | 3.61e-01 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | 28 | 1.19e-01 | -0.170000 | 2.27e-01 |
| ABC-family proteins mediated transport | 94 | 4.42e-03 | -0.170000 | 2.01e-02 |
| DNA Damage/Telomere Stress Induced Senescence | 44 | 5.22e-02 | -0.169000 | 1.22e-01 |
| NGF-stimulated transcription | 33 | 9.26e-02 | -0.169000 | 1.88e-01 |
| Downstream signaling events of B Cell Receptor (BCR) | 80 | 8.96e-03 | -0.169000 | 3.19e-02 |
| cGMP effects | 13 | 2.92e-01 | -0.169000 | 4.40e-01 |
| Glucose metabolism | 83 | 7.81e-03 | -0.169000 | 2.91e-02 |
| TNFR2 non-canonical NF-kB pathway | 96 | 4.31e-03 | -0.169000 | 1.99e-02 |
| Cytosolic tRNA aminoacylation | 24 | 1.53e-01 | 0.168000 | 2.74e-01 |
| MAPK1/MAPK3 signaling | 236 | 9.03e-06 | -0.168000 | 1.43e-04 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | 27 | 1.32e-01 | -0.168000 | 2.44e-01 |
| EML4 and NUDC in mitotic spindle formation | 95 | 4.73e-03 | 0.168000 | 2.08e-02 |
| Thromboxane signalling through TP receptor | 20 | 1.95e-01 | -0.167000 | 3.28e-01 |
| G-protein beta:gamma signalling | 29 | 1.20e-01 | -0.167000 | 2.29e-01 |
| Export of Viral Ribonucleoproteins from Nucleus | 33 | 9.71e-02 | 0.167000 | 1.94e-01 |
| Endogenous sterols | 16 | 2.49e-01 | -0.167000 | 3.89e-01 |
| Activation of HOX genes during differentiation | 71 | 1.53e-02 | -0.166000 | 4.91e-02 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | 71 | 1.53e-02 | -0.166000 | 4.91e-02 |
| APC/C:Cdc20 mediated degradation of Securin | 67 | 1.87e-02 | -0.166000 | 5.65e-02 |
| Sphingolipid metabolism | 77 | 1.18e-02 | -0.166000 | 3.98e-02 |
| ER Quality Control Compartment (ERQC) | 21 | 1.89e-01 | -0.166000 | 3.22e-01 |
| RET signaling | 32 | 1.05e-01 | -0.166000 | 2.06e-01 |
| Stabilization of p53 | 55 | 3.38e-02 | -0.165000 | 8.79e-02 |
| Molecules associated with elastic fibres | 22 | 1.82e-01 | -0.164000 | 3.12e-01 |
| Mitochondrial biogenesis | 89 | 7.52e-03 | -0.164000 | 2.84e-02 |
| Defects in cobalamin (B12) metabolism | 13 | 3.07e-01 | 0.164000 | 4.56e-01 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | 78 | 1.24e-02 | -0.164000 | 4.14e-02 |
| ZBP1(DAI) mediated induction of type I IFNs | 20 | 2.05e-01 | -0.164000 | 3.39e-01 |
| Regulation of PTEN stability and activity | 67 | 2.07e-02 | -0.163000 | 6.09e-02 |
| TICAM1-dependent activation of IRF3/IRF7 | 12 | 3.27e-01 | -0.163000 | 4.77e-01 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | 46 | 5.55e-02 | -0.163000 | 1.28e-01 |
| Transcriptional regulation by RUNX1 | 185 | 1.30e-04 | -0.163000 | 1.30e-03 |
| Lysosphingolipid and LPA receptors | 11 | 3.50e-01 | -0.163000 | 5.00e-01 |
| Disorders of transmembrane transporters | 147 | 6.65e-04 | -0.163000 | 4.96e-03 |
| Translesion Synthesis by POLH | 18 | 2.33e-01 | -0.162000 | 3.72e-01 |
| TCR signaling | 122 | 2.03e-03 | -0.162000 | 1.18e-02 |
| Post NMDA receptor activation events | 50 | 4.80e-02 | -0.162000 | 1.15e-01 |
| CTLA4 inhibitory signaling | 21 | 2.00e-01 | -0.162000 | 3.32e-01 |
| Activation of NMDA receptors and postsynaptic events | 60 | 3.04e-02 | -0.162000 | 8.20e-02 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | 88 | 8.90e-03 | -0.161000 | 3.19e-02 |
| Arachidonic acid metabolism | 44 | 6.45e-02 | -0.161000 | 1.44e-01 |
| HDMs demethylate histones | 22 | 1.91e-01 | -0.161000 | 3.24e-01 |
| Metabolism of nitric oxide: NOS3 activation and regulation | 12 | 3.35e-01 | -0.161000 | 4.85e-01 |
| Negative regulation of MAPK pathway | 42 | 7.16e-02 | -0.161000 | 1.54e-01 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | 12 | 3.35e-01 | 0.161000 | 4.85e-01 |
| Nuclear Pore Complex (NPC) Disassembly | 36 | 9.60e-02 | 0.160000 | 1.93e-01 |
| C-type lectin receptors (CLRs) | 130 | 1.60e-03 | -0.160000 | 9.81e-03 |
| Metabolism of porphyrins | 22 | 1.94e-01 | -0.160000 | 3.27e-01 |
| Diseases of signal transduction by growth factor receptors and second messengers | 343 | 3.63e-07 | -0.160000 | 7.86e-06 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | 10 | 3.82e-01 | -0.160000 | 5.32e-01 |
| Extra-nuclear estrogen signaling | 66 | 2.58e-02 | -0.159000 | 7.22e-02 |
| Translesion synthesis by REV1 | 16 | 2.72e-01 | -0.159000 | 4.16e-01 |
| Protein ubiquitination | 72 | 2.07e-02 | -0.158000 | 6.09e-02 |
| Aflatoxin activation and detoxification | 15 | 2.91e-01 | -0.157000 | 4.39e-01 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | 10 | 3.91e-01 | -0.157000 | 5.41e-01 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | 34 | 1.14e-01 | -0.156000 | 2.21e-01 |
| Cytosolic sensors of pathogen-associated DNA | 62 | 3.33e-02 | -0.156000 | 8.73e-02 |
| TRP channels | 19 | 2.39e-01 | 0.156000 | 3.76e-01 |
| Nucleobase biosynthesis | 13 | 3.30e-01 | -0.156000 | 4.81e-01 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | 18 | 2.52e-01 | -0.156000 | 3.92e-01 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | 18 | 2.52e-01 | -0.156000 | 3.92e-01 |
| RNA Polymerase I Promoter Escape | 47 | 6.44e-02 | -0.156000 | 1.44e-01 |
| Mitotic Spindle Checkpoint | 108 | 5.12e-03 | 0.156000 | 2.20e-02 |
| ADP signalling through P2Y purinoceptor 1 | 21 | 2.16e-01 | -0.156000 | 3.53e-01 |
| FCERI mediated MAPK activation | 90 | 1.06e-02 | 0.156000 | 3.68e-02 |
| Platelet calcium homeostasis | 22 | 2.07e-01 | -0.156000 | 3.41e-01 |
| Diseases of metabolism | 191 | 2.11e-04 | -0.155000 | 1.90e-03 |
| Biosynthesis of specialized proresolving mediators (SPMs) | 16 | 2.82e-01 | -0.155000 | 4.27e-01 |
| rRNA modification in the nucleus and cytosol | 59 | 3.90e-02 | -0.155000 | 9.83e-02 |
| COPI-independent Golgi-to-ER retrograde traffic | 33 | 1.23e-01 | -0.155000 | 2.32e-01 |
| Xenobiotics | 12 | 3.53e-01 | -0.155000 | 5.03e-01 |
| Regulation of RUNX1 Expression and Activity | 18 | 2.55e-01 | 0.155000 | 3.96e-01 |
| Resolution of Abasic Sites (AP sites) | 37 | 1.04e-01 | -0.155000 | 2.04e-01 |
| GABA synthesis, release, reuptake and degradation | 13 | 3.35e-01 | -0.154000 | 4.85e-01 |
| Transport of Mature mRNA Derived from an Intronless Transcript | 42 | 8.44e-02 | 0.154000 | 1.77e-01 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | 12 | 3.57e-01 | 0.153000 | 5.09e-01 |
| RHO GTPases activate KTN1 | 11 | 3.79e-01 | -0.153000 | 5.29e-01 |
| Eicosanoid ligand-binding receptors | 13 | 3.38e-01 | -0.153000 | 4.88e-01 |
| p38MAPK events | 13 | 3.39e-01 | -0.153000 | 4.88e-01 |
| SHC1 events in ERBB4 signaling | 10 | 4.02e-01 | -0.153000 | 5.52e-01 |
| DNA Double Strand Break Response | 47 | 6.97e-02 | -0.153000 | 1.51e-01 |
| Receptor Mediated Mitophagy | 11 | 3.80e-01 | -0.153000 | 5.30e-01 |
| Nucleotide Excision Repair | 110 | 5.69e-03 | -0.153000 | 2.39e-02 |
| Cross-presentation of soluble exogenous antigens (endosomes) | 48 | 6.79e-02 | -0.152000 | 1.49e-01 |
| Cell recruitment (pro-inflammatory response) | 22 | 2.18e-01 | -0.152000 | 3.54e-01 |
| Purinergic signaling in leishmaniasis infection | 22 | 2.18e-01 | -0.152000 | 3.54e-01 |
| Golgi Associated Vesicle Biogenesis | 55 | 5.18e-02 | -0.152000 | 1.22e-01 |
| NoRC negatively regulates rRNA expression | 62 | 3.94e-02 | -0.151000 | 9.87e-02 |
| Phase I - Functionalization of compounds | 64 | 3.65e-02 | -0.151000 | 9.40e-02 |
| Regulation of RAS by GAPs | 67 | 3.29e-02 | -0.151000 | 8.68e-02 |
| VEGFR2 mediated vascular permeability | 26 | 1.84e-01 | -0.151000 | 3.15e-01 |
| HDR through MMEJ (alt-NHEJ) | 10 | 4.11e-01 | 0.150000 | 5.62e-01 |
| MAPK family signaling cascades | 270 | 2.29e-05 | -0.150000 | 3.01e-04 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | 36 | 1.21e-01 | -0.149000 | 2.29e-01 |
| Processing and activation of SUMO | 10 | 4.14e-01 | 0.149000 | 5.64e-01 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | 84 | 1.81e-02 | 0.149000 | 5.52e-02 |
| TNFs bind their physiological receptors | 25 | 1.97e-01 | -0.149000 | 3.29e-01 |
| Neurotransmitter receptors and postsynaptic signal transmission | 127 | 3.80e-03 | -0.149000 | 1.83e-02 |
| Basigin interactions | 23 | 2.18e-01 | -0.148000 | 3.54e-01 |
| Metabolism of proteins | 1722 | 2.43e-24 | -0.147000 | 1.07e-22 |
| Nuclear import of Rev protein | 34 | 1.38e-01 | 0.147000 | 2.52e-01 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | 43 | 9.53e-02 | 0.147000 | 1.92e-01 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | 59 | 5.09e-02 | -0.147000 | 1.20e-01 |
| HCMV Late Events | 69 | 3.49e-02 | -0.147000 | 9.01e-02 |
| Regulation of MECP2 expression and activity | 28 | 1.79e-01 | -0.147000 | 3.08e-01 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | 11 | 4.01e-01 | -0.146000 | 5.51e-01 |
| Synthesis of substrates in N-glycan biosythesis | 58 | 5.49e-02 | -0.146000 | 1.27e-01 |
| TRAF3-dependent IRF activation pathway | 13 | 3.63e-01 | 0.146000 | 5.15e-01 |
| Prostacyclin signalling through prostacyclin receptor | 16 | 3.13e-01 | -0.146000 | 4.62e-01 |
| Acyl chain remodelling of PC | 19 | 2.72e-01 | -0.146000 | 4.15e-01 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | 31 | 1.61e-01 | -0.146000 | 2.85e-01 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | 73 | 3.29e-02 | -0.144000 | 8.68e-02 |
| Negative epigenetic regulation of rRNA expression | 65 | 4.41e-02 | -0.144000 | 1.08e-01 |
| TP53 Regulates Metabolic Genes | 86 | 2.11e-02 | -0.144000 | 6.16e-02 |
| tRNA Aminoacylation | 42 | 1.07e-01 | 0.144000 | 2.09e-01 |
| Vpr-mediated nuclear import of PICs | 34 | 1.47e-01 | 0.144000 | 2.65e-01 |
| HDR through Homologous Recombination (HRR) | 66 | 4.45e-02 | 0.143000 | 1.08e-01 |
| Signaling by WNT in cancer | 30 | 1.79e-01 | -0.142000 | 3.08e-01 |
| Signaling by SCF-KIT | 40 | 1.21e-01 | -0.142000 | 2.29e-01 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | 24 | 2.30e-01 | -0.142000 | 3.69e-01 |
| E3 ubiquitin ligases ubiquitinate target proteins | 52 | 7.77e-02 | -0.141000 | 1.65e-01 |
| Potential therapeutics for SARS | 36 | 1.43e-01 | -0.141000 | 2.59e-01 |
| RA biosynthesis pathway | 13 | 3.78e-01 | -0.141000 | 5.29e-01 |
| Transport of small molecules | 563 | 1.09e-08 | -0.141000 | 2.75e-07 |
| Signaling by BRAF and RAF fusions | 57 | 6.59e-02 | -0.141000 | 1.46e-01 |
| Biosynthesis of DHA-derived SPMs | 14 | 3.63e-01 | -0.141000 | 5.15e-01 |
| MTOR signalling | 39 | 1.30e-01 | -0.140000 | 2.41e-01 |
| Signal amplification | 28 | 1.99e-01 | -0.140000 | 3.32e-01 |
| Diseases associated with glycosylation precursor biosynthesis | 18 | 3.05e-01 | -0.140000 | 4.55e-01 |
| Platelet homeostasis | 70 | 4.38e-02 | -0.139000 | 1.07e-01 |
| activated TAK1 mediates p38 MAPK activation | 19 | 2.93e-01 | -0.139000 | 4.42e-01 |
| Diseases of glycosylation | 111 | 1.13e-02 | -0.139000 | 3.89e-02 |
| Hemostasis | 547 | 2.98e-08 | -0.139000 | 7.01e-07 |
| FCGR3A-mediated IL10 synthesis | 99 | 1.74e-02 | 0.138000 | 5.35e-02 |
| Acyl chain remodelling of PI | 10 | 4.49e-01 | -0.138000 | 6.01e-01 |
| VEGFR2 mediated cell proliferation | 18 | 3.10e-01 | -0.138000 | 4.59e-01 |
| Adrenaline,noradrenaline inhibits insulin secretion | 24 | 2.42e-01 | -0.138000 | 3.82e-01 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | 12 | 4.09e-01 | -0.138000 | 5.59e-01 |
| alpha-linolenic acid (ALA) metabolism | 12 | 4.09e-01 | -0.138000 | 5.59e-01 |
| The canonical retinoid cycle in rods (twilight vision) | 10 | 4.52e-01 | -0.137000 | 6.04e-01 |
| Negative regulation of MET activity | 18 | 3.14e-01 | -0.137000 | 4.63e-01 |
| Glycerophospholipid biosynthesis | 106 | 1.52e-02 | -0.136000 | 4.90e-02 |
| Interactions of Rev with host cellular proteins | 37 | 1.52e-01 | 0.136000 | 2.72e-01 |
| Rap1 signalling | 13 | 3.96e-01 | 0.136000 | 5.46e-01 |
| Circadian Clock | 67 | 5.49e-02 | -0.136000 | 1.27e-01 |
| Regulation of PTEN mRNA translation | 13 | 3.99e-01 | 0.135000 | 5.49e-01 |
| Dual incision in TC-NER | 65 | 6.05e-02 | -0.135000 | 1.37e-01 |
| RUNX3 regulates NOTCH signaling | 14 | 3.83e-01 | -0.135000 | 5.32e-01 |
| Regulation of insulin secretion | 60 | 7.13e-02 | -0.135000 | 1.54e-01 |
| MAPK6/MAPK4 signaling | 83 | 3.42e-02 | -0.134000 | 8.87e-02 |
| Neuronal System | 262 | 1.79e-04 | -0.134000 | 1.70e-03 |
| Transcriptional regulation by small RNAs | 63 | 6.59e-02 | -0.134000 | 1.46e-01 |
| Insulin receptor signalling cascade | 39 | 1.48e-01 | -0.134000 | 2.66e-01 |
| Transcriptional regulation by RUNX3 | 90 | 2.91e-02 | -0.133000 | 7.92e-02 |
| Phase 0 - rapid depolarisation | 29 | 2.15e-01 | 0.133000 | 3.51e-01 |
| CD209 (DC-SIGN) signaling | 20 | 3.04e-01 | -0.133000 | 4.53e-01 |
| Signaling by ERBB2 TMD/JMD mutants | 17 | 3.43e-01 | -0.133000 | 4.93e-01 |
| Methylation | 12 | 4.26e-01 | -0.133000 | 5.77e-01 |
| Death Receptor Signalling | 131 | 8.85e-03 | -0.132000 | 3.19e-02 |
| Tight junction interactions | 19 | 3.18e-01 | -0.132000 | 4.65e-01 |
| Signaling by Retinoic Acid | 32 | 1.96e-01 | -0.132000 | 3.29e-01 |
| Cholesterol biosynthesis | 24 | 2.64e-01 | 0.132000 | 4.06e-01 |
| MET activates RAS signaling | 10 | 4.71e-01 | 0.132000 | 6.16e-01 |
| Metabolic disorders of biological oxidation enzymes | 24 | 2.64e-01 | -0.132000 | 4.07e-01 |
| Downstream signaling of activated FGFR1 | 20 | 3.09e-01 | 0.131000 | 4.58e-01 |
| Signaling by Erythropoietin | 24 | 2.65e-01 | -0.131000 | 4.07e-01 |
| Transcriptional Regulation by E2F6 | 34 | 1.86e-01 | 0.131000 | 3.18e-01 |
| SUMOylation of SUMOylation proteins | 35 | 1.80e-01 | 0.131000 | 3.09e-01 |
| Non-integrin membrane-ECM interactions | 37 | 1.68e-01 | -0.131000 | 2.94e-01 |
| NOTCH4 Intracellular Domain Regulates Transcription | 18 | 3.36e-01 | -0.131000 | 4.86e-01 |
| Regulation of TP53 Expression and Degradation | 36 | 1.76e-01 | -0.130000 | 3.05e-01 |
| Signal Transduction | 1899 | 5.48e-21 | -0.130000 | 2.20e-19 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | 19 | 3.26e-01 | -0.130000 | 4.76e-01 |
| CDK-mediated phosphorylation and removal of Cdc6 | 72 | 5.66e-02 | -0.130000 | 1.30e-01 |
| Costimulation by the CD28 family | 74 | 5.34e-02 | -0.130000 | 1.25e-01 |
| Signaling by FGFR3 | 31 | 2.12e-01 | -0.130000 | 3.48e-01 |
| Asparagine N-linked glycosylation | 269 | 2.53e-04 | -0.130000 | 2.18e-03 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) | 36 | 1.79e-01 | -0.129000 | 3.08e-01 |
| Acyl chain remodelling of PE | 20 | 3.17e-01 | -0.129000 | 4.65e-01 |
| Formation of RNA Pol II elongation complex | 57 | 9.13e-02 | -0.129000 | 1.87e-01 |
| RNA Polymerase II Transcription Elongation | 57 | 9.13e-02 | -0.129000 | 1.87e-01 |
| Glycolysis | 66 | 6.92e-02 | -0.129000 | 1.51e-01 |
| Glutamate and glutamine metabolism | 12 | 4.38e-01 | -0.129000 | 5.91e-01 |
| p53-Dependent G1 DNA Damage Response | 64 | 7.42e-02 | -0.129000 | 1.59e-01 |
| p53-Dependent G1/S DNA damage checkpoint | 64 | 7.42e-02 | -0.129000 | 1.59e-01 |
| G1/S DNA Damage Checkpoints | 66 | 7.17e-02 | -0.128000 | 1.54e-01 |
| O-linked glycosylation | 85 | 4.14e-02 | -0.128000 | 1.03e-01 |
| Beta-oxidation of very long chain fatty acids | 10 | 4.88e-01 | -0.127000 | 6.31e-01 |
| Rev-mediated nuclear export of HIV RNA | 35 | 1.95e-01 | 0.126000 | 3.28e-01 |
| SUMOylation of DNA replication proteins | 46 | 1.38e-01 | 0.126000 | 2.52e-01 |
| Membrane Trafficking | 559 | 3.18e-07 | -0.126000 | 7.01e-06 |
| RNA Polymerase III Transcription Termination | 23 | 2.96e-01 | -0.126000 | 4.45e-01 |
| MHC class II antigen presentation | 101 | 2.88e-02 | -0.126000 | 7.89e-02 |
| G2/M DNA damage checkpoint | 67 | 7.51e-02 | 0.126000 | 1.60e-01 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | 25 | 2.77e-01 | -0.126000 | 4.22e-01 |
| HIV Infection | 225 | 1.21e-03 | -0.125000 | 7.87e-03 |
| CDT1 association with the CDC6:ORC:origin complex | 58 | 9.94e-02 | -0.125000 | 1.97e-01 |
| Immune System | 1897 | 1.74e-19 | -0.125000 | 6.43e-18 |
| Signaling by PDGFRA extracellular domain mutants | 12 | 4.53e-01 | 0.125000 | 6.04e-01 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | 12 | 4.53e-01 | 0.125000 | 6.04e-01 |
| Mitochondrial Fatty Acid Beta-Oxidation | 36 | 1.95e-01 | -0.125000 | 3.28e-01 |
| ECM proteoglycans | 36 | 1.95e-01 | -0.125000 | 3.28e-01 |
| SHC-mediated cascade:FGFR2 | 12 | 4.55e-01 | 0.125000 | 6.05e-01 |
| Purine ribonucleoside monophosphate biosynthesis | 10 | 4.96e-01 | -0.124000 | 6.38e-01 |
| G alpha (12/13) signalling events | 68 | 7.64e-02 | -0.124000 | 1.63e-01 |
| Assembly of the pre-replicative complex | 67 | 7.98e-02 | -0.124000 | 1.68e-01 |
| Signaling by FGFR4 in disease | 11 | 4.78e-01 | 0.124000 | 6.22e-01 |
| Interleukin receptor SHC signaling | 23 | 3.06e-01 | -0.123000 | 4.56e-01 |
| RAB GEFs exchange GTP for GDP on RABs | 87 | 4.69e-02 | -0.123000 | 1.14e-01 |
| Nitric oxide stimulates guanylate cyclase | 16 | 3.97e-01 | -0.122000 | 5.47e-01 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | 17 | 3.83e-01 | 0.122000 | 5.32e-01 |
| G alpha (i) signalling events | 246 | 9.90e-04 | -0.122000 | 6.63e-03 |
| Ion channel transport | 136 | 1.42e-02 | -0.122000 | 4.62e-02 |
| Cell-cell junction organization | 38 | 1.94e-01 | -0.122000 | 3.27e-01 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | 32 | 2.33e-01 | -0.122000 | 3.72e-01 |
| HCMV Infection | 96 | 3.93e-02 | -0.122000 | 9.87e-02 |
| Processing of Capped Intron-Containing Pre-mRNA | 238 | 1.23e-03 | -0.122000 | 7.90e-03 |
| SCF(Skp2)-mediated degradation of p27/p21 | 60 | 1.04e-01 | -0.121000 | 2.04e-01 |
| Signaling by FGFR3 in disease | 13 | 4.49e-01 | 0.121000 | 6.01e-01 |
| Signaling by FGFR3 point mutants in cancer | 13 | 4.49e-01 | 0.121000 | 6.01e-01 |
| Alpha-protein kinase 1 signaling pathway | 11 | 4.86e-01 | -0.121000 | 6.30e-01 |
| Interleukin-4 and Interleukin-13 signaling | 94 | 4.37e-02 | -0.120000 | 1.07e-01 |
| Transmission across Chemical Synapses | 173 | 6.33e-03 | -0.120000 | 2.56e-02 |
| Signaling by PDGFR in disease | 19 | 3.64e-01 | 0.120000 | 5.16e-01 |
| Dectin-2 family | 19 | 3.67e-01 | -0.120000 | 5.19e-01 |
| Downstream signaling of activated FGFR2 | 19 | 3.68e-01 | 0.119000 | 5.19e-01 |
| Striated Muscle Contraction | 25 | 3.02e-01 | -0.119000 | 4.51e-01 |
| Regulation of TP53 Activity through Methylation | 19 | 3.68e-01 | -0.119000 | 5.19e-01 |
| Tryptophan catabolism | 12 | 4.76e-01 | 0.119000 | 6.22e-01 |
| Mitotic Prometaphase | 185 | 5.37e-03 | 0.119000 | 2.28e-02 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | 37 | 2.12e-01 | -0.119000 | 3.48e-01 |
| Frs2-mediated activation | 11 | 4.96e-01 | -0.119000 | 6.38e-01 |
| Intrinsic Pathway for Apoptosis | 53 | 1.36e-01 | -0.118000 | 2.50e-01 |
| RORA activates gene expression | 18 | 3.85e-01 | -0.118000 | 5.33e-01 |
| Signaling by FGFR1 in disease | 31 | 2.55e-01 | 0.118000 | 3.96e-01 |
| Regulation of TP53 Degradation | 35 | 2.28e-01 | -0.118000 | 3.66e-01 |
| Visual phototransduction | 60 | 1.17e-01 | -0.117000 | 2.25e-01 |
| Regulation of TP53 Activity through Phosphorylation | 89 | 5.63e-02 | 0.117000 | 1.30e-01 |
| Polymerase switching on the C-strand of the telomere | 26 | 3.03e-01 | -0.117000 | 4.52e-01 |
| Rho GTPase cycle | 125 | 2.43e-02 | -0.117000 | 6.89e-02 |
| Inflammasomes | 20 | 3.69e-01 | -0.116000 | 5.20e-01 |
| G1/S-Specific Transcription | 29 | 2.80e-01 | 0.116000 | 4.26e-01 |
| Phospholipid metabolism | 184 | 6.76e-03 | -0.116000 | 2.67e-02 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | 72 | 8.97e-02 | -0.116000 | 1.85e-01 |
| RNA Polymerase III Transcription Initiation | 36 | 2.31e-01 | -0.115000 | 3.70e-01 |
| Fertilization | 13 | 4.73e-01 | -0.115000 | 6.18e-01 |
| RNA polymerase II transcribes snRNA genes | 72 | 9.65e-02 | 0.113000 | 1.93e-01 |
| Diseases associated with O-glycosylation of proteins | 50 | 1.67e-01 | -0.113000 | 2.93e-01 |
| Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) | 10 | 5.37e-01 | 0.113000 | 6.67e-01 |
| Postmitotic nuclear pore complex (NPC) reformation | 27 | 3.11e-01 | 0.113000 | 4.60e-01 |
| IRS-related events triggered by IGF1R | 35 | 2.49e-01 | -0.113000 | 3.89e-01 |
| PCNA-Dependent Long Patch Base Excision Repair | 21 | 3.72e-01 | -0.113000 | 5.23e-01 |
| Mitochondrial iron-sulfur cluster biogenesis | 13 | 4.83e-01 | -0.112000 | 6.27e-01 |
| Peptide ligand-binding receptors | 97 | 5.61e-02 | -0.112000 | 1.30e-01 |
| Deadenylation of mRNA | 22 | 3.62e-01 | 0.112000 | 5.15e-01 |
| RHO GTPases activate IQGAPs | 11 | 5.21e-01 | -0.112000 | 6.53e-01 |
| Platelet sensitization by LDL | 16 | 4.39e-01 | -0.112000 | 5.91e-01 |
| Regulation of IFNG signaling | 14 | 4.70e-01 | 0.112000 | 6.15e-01 |
| COPI-mediated anterograde transport | 78 | 9.13e-02 | -0.111000 | 1.87e-01 |
| Nucleobase catabolism | 28 | 3.11e-01 | -0.111000 | 4.60e-01 |
| Signaling by FGFR2 in disease | 32 | 2.80e-01 | -0.110000 | 4.26e-01 |
| Cytochrome c-mediated apoptotic response | 13 | 4.91e-01 | 0.110000 | 6.34e-01 |
| Interleukin-10 signaling | 37 | 2.47e-01 | -0.110000 | 3.87e-01 |
| Pyruvate metabolism and Citric Acid (TCA) cycle | 52 | 1.70e-01 | -0.110000 | 2.96e-01 |
| Transport to the Golgi and subsequent modification | 155 | 1.85e-02 | -0.110000 | 5.61e-02 |
| Prolactin receptor signaling | 11 | 5.29e-01 | 0.110000 | 6.60e-01 |
| Processing of Capped Intronless Pre-mRNA | 28 | 3.17e-01 | -0.109000 | 4.65e-01 |
| Interleukin-27 signaling | 11 | 5.34e-01 | 0.108000 | 6.65e-01 |
| Caspase activation via Death Receptors in the presence of ligand | 16 | 4.56e-01 | 0.108000 | 6.06e-01 |
| Blood group systems biosynthesis | 17 | 4.44e-01 | -0.107000 | 5.96e-01 |
| FRS-mediated FGFR2 signaling | 14 | 4.88e-01 | 0.107000 | 6.31e-01 |
| Amino acid transport across the plasma membrane | 24 | 3.65e-01 | -0.107000 | 5.17e-01 |
| tRNA processing in the nucleus | 59 | 1.56e-01 | 0.107000 | 2.78e-01 |
| RNA Polymerase II Transcription Termination | 65 | 1.37e-01 | -0.107000 | 2.51e-01 |
| Nucleotide-like (purinergic) receptors | 13 | 5.06e-01 | -0.107000 | 6.44e-01 |
| Voltage gated Potassium channels | 27 | 3.39e-01 | -0.106000 | 4.88e-01 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | 73 | 1.18e-01 | -0.106000 | 2.27e-01 |
| Cellular hexose transport | 15 | 4.78e-01 | -0.106000 | 6.22e-01 |
| Generation of second messenger molecules | 38 | 2.62e-01 | -0.105000 | 4.05e-01 |
| Epigenetic regulation of gene expression | 103 | 6.71e-02 | -0.104000 | 1.48e-01 |
| APC/C:Cdc20 mediated degradation of Cyclin B | 24 | 3.76e-01 | -0.104000 | 5.28e-01 |
| Chromosome Maintenance | 105 | 6.49e-02 | -0.104000 | 1.45e-01 |
| Receptor-type tyrosine-protein phosphatases | 12 | 5.32e-01 | -0.104000 | 6.63e-01 |
| Unfolded Protein Response (UPR) | 88 | 9.15e-02 | -0.104000 | 1.87e-01 |
| Signaling by ERBB2 in Cancer | 21 | 4.10e-01 | -0.104000 | 5.61e-01 |
| Apoptosis | 168 | 2.06e-02 | -0.103000 | 6.09e-02 |
| IRS-mediated signalling | 34 | 2.96e-01 | -0.103000 | 4.45e-01 |
| Transcriptional regulation of white adipocyte differentiation | 77 | 1.17e-01 | -0.103000 | 2.25e-01 |
| Transport of inorganic cations/anions and amino acids/oligopeptides | 80 | 1.11e-01 | -0.103000 | 2.16e-01 |
| SHC-mediated cascade:FGFR1 | 12 | 5.37e-01 | 0.103000 | 6.67e-01 |
| IGF1R signaling cascade | 36 | 2.85e-01 | -0.103000 | 4.31e-01 |
| Interleukin-12 signaling | 44 | 2.38e-01 | -0.103000 | 3.75e-01 |
| Sulfur amino acid metabolism | 23 | 3.94e-01 | -0.103000 | 5.45e-01 |
| Heme biosynthesis | 14 | 5.07e-01 | -0.102000 | 6.44e-01 |
| Gene Silencing by RNA | 88 | 9.72e-02 | -0.102000 | 1.94e-01 |
| Signaling by Hippo | 18 | 4.53e-01 | 0.102000 | 6.04e-01 |
| Translesion synthesis by POLI | 17 | 4.66e-01 | -0.102000 | 6.13e-01 |
| Interleukin-2 family signaling | 38 | 2.77e-01 | -0.102000 | 4.22e-01 |
| Fatty acid metabolism | 153 | 3.07e-02 | -0.101000 | 8.25e-02 |
| Activation of the pre-replicative complex | 32 | 3.23e-01 | 0.101000 | 4.71e-01 |
| Cyclin A:Cdk2-associated events at S phase entry | 85 | 1.08e-01 | -0.101000 | 2.11e-01 |
| Nuclear Envelope Breakdown | 53 | 2.06e-01 | 0.100000 | 3.40e-01 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | 36 | 2.98e-01 | -0.100000 | 4.46e-01 |
| mRNA Capping | 29 | 3.50e-01 | -0.100000 | 5.01e-01 |
| Response of EIF2AK1 (HRI) to heme deficiency | 14 | 5.18e-01 | 0.099700 | 6.51e-01 |
| Oncogenic MAPK signaling | 73 | 1.43e-01 | -0.099200 | 2.59e-01 |
| SLC transporter disorders | 76 | 1.36e-01 | -0.098900 | 2.50e-01 |
| RAB geranylgeranylation | 62 | 1.79e-01 | -0.098800 | 3.08e-01 |
| Protein methylation | 15 | 5.08e-01 | -0.098700 | 6.44e-01 |
| Transcriptional regulation by RUNX2 | 102 | 8.51e-02 | -0.098600 | 1.78e-01 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | 14 | 5.23e-01 | 0.098600 | 6.55e-01 |
| Formation of the cornified envelope | 21 | 4.35e-01 | -0.098400 | 5.88e-01 |
| Misspliced GSK3beta mutants stabilize beta-catenin | 15 | 5.10e-01 | -0.098300 | 6.44e-01 |
| S33 mutants of beta-catenin aren't phosphorylated | 15 | 5.10e-01 | -0.098300 | 6.44e-01 |
| S37 mutants of beta-catenin aren't phosphorylated | 15 | 5.10e-01 | -0.098300 | 6.44e-01 |
| S45 mutants of beta-catenin aren't phosphorylated | 15 | 5.10e-01 | -0.098300 | 6.44e-01 |
| T41 mutants of beta-catenin aren't phosphorylated | 15 | 5.10e-01 | -0.098300 | 6.44e-01 |
| phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex | 15 | 5.10e-01 | -0.098300 | 6.44e-01 |
| Recognition of DNA damage by PCNA-containing replication complex | 30 | 3.52e-01 | -0.098200 | 5.03e-01 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | 19 | 4.61e-01 | 0.097800 | 6.09e-01 |
| Branched-chain amino acid catabolism | 21 | 4.38e-01 | 0.097700 | 5.91e-01 |
| DAP12 signaling | 28 | 3.71e-01 | -0.097700 | 5.22e-01 |
| Cyclin E associated events during G1/S transition | 83 | 1.24e-01 | -0.097500 | 2.33e-01 |
| Class A/1 (Rhodopsin-like receptors) | 170 | 2.83e-02 | -0.097500 | 7.78e-02 |
| L1CAM interactions | 85 | 1.20e-01 | -0.097500 | 2.29e-01 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | 179 | 2.45e-02 | -0.097500 | 6.93e-02 |
| Mitochondrial tRNA aminoacylation | 21 | 4.40e-01 | 0.097400 | 5.91e-01 |
| Regulation of RUNX2 expression and activity | 67 | 1.70e-01 | -0.096900 | 2.96e-01 |
| Processive synthesis on the C-strand of the telomere | 19 | 4.66e-01 | -0.096500 | 6.13e-01 |
| Downstream signaling of activated FGFR3 | 16 | 5.05e-01 | 0.096200 | 6.44e-01 |
| Translesion synthesis by POLK | 17 | 4.94e-01 | -0.095800 | 6.37e-01 |
| Activation of G protein gated Potassium channels | 20 | 4.58e-01 | 0.095800 | 6.06e-01 |
| G protein gated Potassium channels | 20 | 4.58e-01 | 0.095800 | 6.06e-01 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | 20 | 4.58e-01 | 0.095800 | 6.06e-01 |
| TP53 Regulates Transcription of DNA Repair Genes | 61 | 1.96e-01 | -0.095600 | 3.29e-01 |
| Signaling by Rho GTPases | 365 | 1.78e-03 | -0.095200 | 1.07e-02 |
| GPCR ligand binding | 237 | 1.17e-02 | -0.095100 | 3.96e-02 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | 43 | 2.81e-01 | -0.095100 | 4.26e-01 |
| Unblocking of NMDA receptors, glutamate binding and activation | 13 | 5.54e-01 | -0.094700 | 6.85e-01 |
| Signaling by NTRK3 (TRKC) | 16 | 5.12e-01 | -0.094700 | 6.45e-01 |
| Neddylation | 219 | 1.62e-02 | -0.094200 | 5.12e-02 |
| Metabolism of non-coding RNA | 53 | 2.35e-01 | 0.094200 | 3.73e-01 |
| snRNP Assembly | 53 | 2.35e-01 | 0.094200 | 3.73e-01 |
| Regulation of lipid metabolism by PPARalpha | 106 | 9.45e-02 | -0.094000 | 1.91e-01 |
| Removal of the Flap Intermediate from the C-strand | 17 | 5.03e-01 | -0.093800 | 6.44e-01 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | 75 | 1.63e-01 | -0.093200 | 2.87e-01 |
| Regulated proteolysis of p75NTR | 11 | 5.96e-01 | -0.092400 | 7.17e-01 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | 23 | 4.43e-01 | -0.092300 | 5.96e-01 |
| Programmed Cell Death | 171 | 3.73e-02 | -0.092300 | 9.52e-02 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | 12 | 5.80e-01 | -0.092300 | 7.09e-01 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | 76 | 1.66e-01 | -0.091900 | 2.92e-01 |
| Insulin processing | 20 | 4.77e-01 | 0.091900 | 6.22e-01 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | 11 | 5.99e-01 | -0.091600 | 7.17e-01 |
| Assembly of active LPL and LIPC lipase complexes | 11 | 5.99e-01 | -0.091500 | 7.17e-01 |
| mRNA decay by 3' to 5' exoribonuclease | 16 | 5.27e-01 | -0.091300 | 6.58e-01 |
| RHO GTPases Activate Formins | 117 | 9.00e-02 | 0.090700 | 1.85e-01 |
| Signaling by cytosolic FGFR1 fusion mutants | 18 | 5.07e-01 | 0.090400 | 6.44e-01 |
| Caspase activation via extrinsic apoptotic signalling pathway | 25 | 4.34e-01 | 0.090300 | 5.88e-01 |
| Telomere Extension By Telomerase | 23 | 4.55e-01 | -0.089900 | 6.05e-01 |
| Interactions of Vpr with host cellular proteins | 37 | 3.44e-01 | 0.089900 | 4.94e-01 |
| Meiotic synapsis | 45 | 2.97e-01 | -0.089900 | 4.45e-01 |
| PPARA activates gene expression | 104 | 1.13e-01 | -0.089900 | 2.19e-01 |
| RUNX2 regulates osteoblast differentiation | 19 | 5.00e-01 | -0.089500 | 6.42e-01 |
| Synthesis, secretion, and deacylation of Ghrelin | 11 | 6.08e-01 | -0.089400 | 7.25e-01 |
| Glutathione synthesis and recycling | 10 | 6.26e-01 | -0.088900 | 7.43e-01 |
| FRS-mediated FGFR1 signaling | 14 | 5.66e-01 | 0.088600 | 6.96e-01 |
| EPHB-mediated forward signaling | 33 | 3.81e-01 | -0.088100 | 5.31e-01 |
| PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases | 13 | 5.83e-01 | -0.088000 | 7.09e-01 |
| Regulation of beta-cell development | 20 | 4.96e-01 | -0.087900 | 6.38e-01 |
| Leishmania infection | 246 | 1.80e-02 | -0.087600 | 5.50e-02 |
| Muscle contraction | 144 | 6.98e-02 | -0.087500 | 1.52e-01 |
| Metabolism of lipids | 623 | 1.92e-04 | -0.087500 | 1.77e-03 |
| Global Genome Nucleotide Excision Repair (GG-NER) | 84 | 1.68e-01 | -0.087100 | 2.94e-01 |
| Metabolism of steroid hormones | 20 | 5.01e-01 | -0.087000 | 6.42e-01 |
| mRNA decay by 5' to 3' exoribonuclease | 15 | 5.61e-01 | -0.086800 | 6.91e-01 |
| Cytosolic sulfonation of small molecules | 19 | 5.13e-01 | -0.086800 | 6.45e-01 |
| G0 and Early G1 | 27 | 4.36e-01 | 0.086600 | 5.89e-01 |
| O-glycosylation of TSR domain-containing proteins | 28 | 4.29e-01 | -0.086300 | 5.81e-01 |
| Glutamate Neurotransmitter Release Cycle | 20 | 5.04e-01 | -0.086300 | 6.44e-01 |
| STING mediated induction of host immune responses | 15 | 5.65e-01 | -0.085700 | 6.95e-01 |
| Orc1 removal from chromatin | 70 | 2.15e-01 | -0.085700 | 3.51e-01 |
| Translocation of ZAP-70 to Immunological synapse | 24 | 4.68e-01 | -0.085600 | 6.14e-01 |
| Post-translational protein modification | 1197 | 6.81e-07 | -0.085200 | 1.43e-05 |
| PI-3K cascade:FGFR4 | 10 | 6.41e-01 | -0.085100 | 7.55e-01 |
| RUNX3 regulates p14-ARF | 10 | 6.42e-01 | 0.084900 | 7.55e-01 |
| Signaling by FGFR1 | 38 | 3.66e-01 | -0.084800 | 5.17e-01 |
| Regulation of APC/C activators between G1/S and early anaphase | 80 | 1.91e-01 | -0.084600 | 3.24e-01 |
| RNA Polymerase I Transcription Initiation | 47 | 3.18e-01 | -0.084100 | 4.66e-01 |
| Synthesis of PIPs at the plasma membrane | 52 | 2.96e-01 | -0.083800 | 4.45e-01 |
| DNA Replication Pre-Initiation | 83 | 1.89e-01 | -0.083400 | 3.22e-01 |
| RHO GTPase Effectors | 249 | 2.40e-02 | -0.083000 | 6.85e-02 |
| Extension of Telomeres | 51 | 3.07e-01 | -0.082600 | 4.57e-01 |
| Cellular response to heat stress | 93 | 1.70e-01 | -0.082300 | 2.96e-01 |
| Signaling by ERBB2 KD Mutants | 20 | 5.26e-01 | -0.081800 | 6.58e-01 |
| O-linked glycosylation of mucins | 47 | 3.33e-01 | -0.081600 | 4.83e-01 |
| Vesicle-mediated transport | 649 | 3.93e-04 | -0.081500 | 3.21e-03 |
| Phosphorylation of CD3 and TCR zeta chains | 27 | 4.64e-01 | -0.081500 | 6.12e-01 |
| Biological oxidations | 137 | 1.01e-01 | -0.081200 | 1.99e-01 |
| ER to Golgi Anterograde Transport | 129 | 1.11e-01 | -0.081100 | 2.17e-01 |
| AMER1 mutants destabilize the destruction complex | 14 | 6.00e-01 | -0.081000 | 7.17e-01 |
| APC truncation mutants have impaired AXIN binding | 14 | 6.00e-01 | -0.081000 | 7.17e-01 |
| AXIN missense mutants destabilize the destruction complex | 14 | 6.00e-01 | -0.081000 | 7.17e-01 |
| AXIN mutants destabilize the destruction complex, activating WNT signaling | 14 | 6.00e-01 | -0.081000 | 7.17e-01 |
| Truncations of AMER1 destabilize the destruction complex | 14 | 6.00e-01 | -0.081000 | 7.17e-01 |
| truncated APC mutants destabilize the destruction complex | 14 | 6.00e-01 | -0.081000 | 7.17e-01 |
| Triglyceride catabolism | 16 | 5.75e-01 | -0.081000 | 7.03e-01 |
| Netrin-1 signaling | 40 | 3.77e-01 | -0.080700 | 5.29e-01 |
| Signaling by GPCR | 547 | 1.25e-03 | -0.080700 | 8.02e-03 |
| Cytokine Signaling in Immune system | 738 | 2.05e-04 | -0.080200 | 1.86e-03 |
| Stimuli-sensing channels | 75 | 2.32e-01 | -0.079900 | 3.70e-01 |
| PD-1 signaling | 28 | 4.65e-01 | -0.079700 | 6.13e-01 |
| SLC-mediated transmembrane transport | 180 | 6.56e-02 | -0.079600 | 1.46e-01 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | 22 | 5.19e-01 | -0.079500 | 6.51e-01 |
| RNA Polymerase III Abortive And Retractive Initiation | 41 | 3.79e-01 | -0.079400 | 5.29e-01 |
| RNA Polymerase III Transcription | 41 | 3.79e-01 | -0.079400 | 5.29e-01 |
| Cell Cycle Checkpoints | 259 | 2.84e-02 | 0.079100 | 7.80e-02 |
| Processing of DNA double-strand break ends | 71 | 2.50e-01 | 0.078900 | 3.90e-01 |
| Telomere C-strand (Lagging Strand) Synthesis | 34 | 4.26e-01 | -0.078900 | 5.77e-01 |
| Defective B3GALTL causes Peters-plus syndrome (PpS) | 27 | 4.79e-01 | -0.078800 | 6.22e-01 |
| EPHA-mediated growth cone collapse | 13 | 6.26e-01 | -0.078100 | 7.43e-01 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | 24 | 5.10e-01 | -0.077700 | 6.44e-01 |
| TP53 Regulates Transcription of Death Receptors and Ligands | 12 | 6.42e-01 | -0.077400 | 7.55e-01 |
| Bile acid and bile salt metabolism | 28 | 4.79e-01 | 0.077200 | 6.23e-01 |
| GPCR downstream signalling | 502 | 3.37e-03 | -0.076400 | 1.70e-02 |
| APC-Cdc20 mediated degradation of Nek2A | 26 | 5.03e-01 | -0.075900 | 6.44e-01 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | 73 | 2.63e-01 | -0.075700 | 4.06e-01 |
| SUMO E3 ligases SUMOylate target proteins | 161 | 9.73e-02 | -0.075700 | 1.94e-01 |
| Signalling to ERKs | 31 | 4.67e-01 | -0.075600 | 6.13e-01 |
| Laminin interactions | 21 | 5.49e-01 | -0.075500 | 6.80e-01 |
| Golgi-to-ER retrograde transport | 111 | 1.70e-01 | -0.075300 | 2.96e-01 |
| Interferon gamma signaling | 83 | 2.36e-01 | 0.075300 | 3.73e-01 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | 18 | 5.81e-01 | -0.075200 | 7.09e-01 |
| PI Metabolism | 79 | 2.51e-01 | -0.074700 | 3.91e-01 |
| Metal ion SLC transporters | 21 | 5.57e-01 | -0.074000 | 6.87e-01 |
| Carboxyterminal post-translational modifications of tubulin | 27 | 5.12e-01 | -0.072900 | 6.45e-01 |
| Synthesis of glycosylphosphatidylinositol (GPI) | 17 | 6.06e-01 | 0.072200 | 7.24e-01 |
| Myogenesis | 21 | 5.67e-01 | -0.072100 | 6.96e-01 |
| Regulation of TNFR1 signaling | 32 | 4.86e-01 | -0.071200 | 6.30e-01 |
| Regulation of pyruvate dehydrogenase (PDH) complex | 15 | 6.34e-01 | 0.071100 | 7.49e-01 |
| MASTL Facilitates Mitotic Progression | 10 | 6.98e-01 | 0.070900 | 7.97e-01 |
| Intra-Golgi traffic | 43 | 4.22e-01 | -0.070800 | 5.73e-01 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | 104 | 2.15e-01 | 0.070400 | 3.51e-01 |
| Plasma lipoprotein remodeling | 19 | 5.95e-01 | -0.070400 | 7.17e-01 |
| FRS-mediated FGFR3 signaling | 11 | 6.87e-01 | 0.070100 | 7.90e-01 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | 13 | 6.65e-01 | 0.069400 | 7.74e-01 |
| Interleukin-12 family signaling | 54 | 3.83e-01 | -0.068600 | 5.32e-01 |
| Synthesis of bile acids and bile salts | 24 | 5.63e-01 | 0.068300 | 6.93e-01 |
| Signaling by MET | 61 | 3.57e-01 | -0.068200 | 5.08e-01 |
| Defects in vitamin and cofactor metabolism | 21 | 5.91e-01 | 0.067800 | 7.14e-01 |
| Purine salvage | 12 | 6.89e-01 | -0.066800 | 7.91e-01 |
| Switching of origins to a post-replicative state | 90 | 2.83e-01 | -0.065400 | 4.29e-01 |
| Energy dependent regulation of mTOR by LKB1-AMPK | 28 | 5.50e-01 | -0.065300 | 6.80e-01 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | 16 | 6.52e-01 | 0.065100 | 7.64e-01 |
| Adaptive Immune System | 758 | 2.30e-03 | -0.065100 | 1.28e-02 |
| Cohesin Loading onto Chromatin | 10 | 7.22e-01 | 0.065000 | 8.13e-01 |
| TNF signaling | 42 | 4.67e-01 | -0.064900 | 6.13e-01 |
| Prolonged ERK activation events | 13 | 6.86e-01 | -0.064800 | 7.90e-01 |
| Mitotic Telophase/Cytokinesis | 13 | 6.87e-01 | 0.064600 | 7.90e-01 |
| Interleukin-37 signaling | 19 | 6.26e-01 | -0.064500 | 7.43e-01 |
| IRAK4 deficiency (TLR2/4) | 10 | 7.25e-01 | -0.064300 | 8.14e-01 |
| MyD88 deficiency (TLR2/4) | 10 | 7.25e-01 | -0.064300 | 8.14e-01 |
| Transcriptional Regulation by TP53 | 352 | 3.99e-02 | -0.063700 | 9.99e-02 |
| Inwardly rectifying K+ channels | 24 | 5.89e-01 | 0.063700 | 7.14e-01 |
| Fanconi Anemia Pathway | 36 | 5.10e-01 | 0.063400 | 6.44e-01 |
| tRNA processing | 136 | 2.05e-01 | -0.063000 | 3.39e-01 |
| KSRP (KHSRP) binds and destabilizes mRNA | 17 | 6.54e-01 | -0.062800 | 7.66e-01 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | 63 | 3.90e-01 | -0.062600 | 5.40e-01 |
| Transport of bile salts and organic acids, metal ions and amine compounds | 55 | 4.22e-01 | -0.062600 | 5.73e-01 |
| Peroxisomal protein import | 57 | 4.17e-01 | -0.062200 | 5.68e-01 |
| Vitamin B5 (pantothenate) metabolism | 17 | 6.60e-01 | 0.061600 | 7.70e-01 |
| SUMOylation | 167 | 1.70e-01 | -0.061500 | 2.96e-01 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | 17 | 6.61e-01 | 0.061400 | 7.70e-01 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | 17 | 6.61e-01 | 0.061400 | 7.70e-01 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | 20 | 6.35e-01 | -0.061400 | 7.49e-01 |
| Zinc transporters | 14 | 6.91e-01 | -0.061400 | 7.93e-01 |
| Homology Directed Repair | 110 | 2.66e-01 | 0.061300 | 4.09e-01 |
| Transcriptional regulation of pluripotent stem cells | 21 | 6.27e-01 | 0.061300 | 7.43e-01 |
| G alpha (s) signalling events | 145 | 2.03e-01 | 0.061300 | 3.37e-01 |
| DNA Double-Strand Break Repair | 135 | 2.20e-01 | 0.061100 | 3.57e-01 |
| Telomere C-strand synthesis initiation | 13 | 7.04e-01 | -0.060900 | 8.02e-01 |
| Transcriptional activation of mitochondrial biogenesis | 51 | 4.58e-01 | -0.060100 | 6.06e-01 |
| Metabolism of folate and pterines | 17 | 6.69e-01 | 0.059900 | 7.77e-01 |
| RHO GTPases activate PAKs | 20 | 6.43e-01 | -0.059800 | 7.55e-01 |
| ADP signalling through P2Y purinoceptor 12 | 18 | 6.62e-01 | -0.059500 | 7.71e-01 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | 16 | 6.81e-01 | -0.059400 | 7.85e-01 |
| Pyruvate metabolism | 28 | 5.87e-01 | -0.059300 | 7.13e-01 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | 28 | 5.90e-01 | -0.058900 | 7.14e-01 |
| APC/C-mediated degradation of cell cycle proteins | 87 | 3.49e-01 | -0.058100 | 5.00e-01 |
| Regulation of mitotic cell cycle | 87 | 3.49e-01 | -0.058100 | 5.00e-01 |
| COPII-mediated vesicle transport | 65 | 4.21e-01 | -0.057700 | 5.73e-01 |
| Regulation of actin dynamics for phagocytic cup formation | 123 | 2.71e-01 | 0.057400 | 4.15e-01 |
| G-protein activation | 23 | 6.34e-01 | -0.057300 | 7.49e-01 |
| HIV Life Cycle | 144 | 2.38e-01 | -0.057000 | 3.75e-01 |
| Interleukin-6 signaling | 10 | 7.57e-01 | -0.056400 | 8.42e-01 |
| Intraflagellar transport | 39 | 5.43e-01 | -0.056200 | 6.73e-01 |
| IKK complex recruitment mediated by RIP1 | 23 | 6.41e-01 | -0.056100 | 7.55e-01 |
| SUMOylation of DNA damage response and repair proteins | 77 | 3.95e-01 | 0.056000 | 5.45e-01 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | 51 | 4.91e-01 | -0.055800 | 6.34e-01 |
| Activation of GABAB receptors | 31 | 5.91e-01 | -0.055700 | 7.14e-01 |
| GABA B receptor activation | 31 | 5.91e-01 | -0.055700 | 7.14e-01 |
| Transport of vitamins, nucleosides, and related molecules | 33 | 5.82e-01 | -0.055400 | 7.09e-01 |
| Leading Strand Synthesis | 14 | 7.23e-01 | 0.054800 | 8.13e-01 |
| Polymerase switching | 14 | 7.23e-01 | 0.054800 | 8.13e-01 |
| ABC transporters in lipid homeostasis | 14 | 7.25e-01 | -0.054400 | 8.14e-01 |
| Ion transport by P-type ATPases | 43 | 5.38e-01 | -0.054300 | 6.67e-01 |
| Lysine catabolism | 11 | 7.55e-01 | 0.054300 | 8.41e-01 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | 38 | 5.70e-01 | -0.053200 | 6.98e-01 |
| RUNX2 regulates bone development | 24 | 6.55e-01 | -0.052700 | 7.66e-01 |
| Synthesis of very long-chain fatty acyl-CoAs | 22 | 6.71e-01 | -0.052300 | 7.78e-01 |
| Nuclear Envelope (NE) Reassembly | 69 | 4.53e-01 | -0.052300 | 6.04e-01 |
| Processing of Intronless Pre-mRNAs | 19 | 6.94e-01 | 0.052100 | 7.95e-01 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | 184 | 2.26e-01 | -0.051700 | 3.64e-01 |
| PI-3K cascade:FGFR2 | 12 | 7.58e-01 | 0.051400 | 8.42e-01 |
| mRNA 3'-end processing | 56 | 5.06e-01 | -0.051400 | 6.44e-01 |
| FCGR3A-mediated phagocytosis | 121 | 3.32e-01 | 0.051100 | 4.82e-01 |
| Leishmania phagocytosis | 121 | 3.32e-01 | 0.051100 | 4.82e-01 |
| Parasite infection | 121 | 3.32e-01 | 0.051100 | 4.82e-01 |
| Phosphorylation of the APC/C | 20 | 6.93e-01 | 0.051000 | 7.95e-01 |
| Meiotic recombination | 38 | 5.87e-01 | -0.051000 | 7.13e-01 |
| Metalloprotease DUBs | 21 | 6.87e-01 | -0.050800 | 7.90e-01 |
| Separation of Sister Chromatids | 168 | 2.58e-01 | 0.050500 | 3.99e-01 |
| Retrograde transport at the Trans-Golgi-Network | 49 | 5.41e-01 | -0.050400 | 6.71e-01 |
| Signaling by PDGF | 44 | 5.64e-01 | -0.050300 | 6.94e-01 |
| Synthesis of PIPs at the Golgi membrane | 16 | 7.30e-01 | -0.049900 | 8.18e-01 |
| Miscellaneous transport and binding events | 20 | 7.01e-01 | -0.049600 | 8.00e-01 |
| Erythropoietin activates RAS | 13 | 7.60e-01 | -0.049000 | 8.42e-01 |
| Synthesis of IP2, IP, and Ins in the cytosol | 13 | 7.60e-01 | 0.048900 | 8.42e-01 |
| PERK regulates gene expression | 31 | 6.39e-01 | 0.048700 | 7.53e-01 |
| tRNA modification in the nucleus and cytosol | 43 | 5.82e-01 | 0.048600 | 7.09e-01 |
| Cell surface interactions at the vascular wall | 174 | 2.70e-01 | -0.048500 | 4.13e-01 |
| Class I MHC mediated antigen processing & presentation | 349 | 1.20e-01 | -0.048400 | 2.29e-01 |
| Fatty acyl-CoA biosynthesis | 34 | 6.26e-01 | -0.048300 | 7.43e-01 |
| Deubiquitination | 242 | 1.97e-01 | -0.048200 | 3.29e-01 |
| Phase 2 - plateau phase | 17 | 7.31e-01 | 0.048100 | 8.19e-01 |
| Anchoring of the basal body to the plasma membrane | 97 | 4.17e-01 | 0.047700 | 5.68e-01 |
| IL-6-type cytokine receptor ligand interactions | 13 | 7.66e-01 | 0.047600 | 8.47e-01 |
| Amine ligand-binding receptors | 10 | 7.96e-01 | 0.047100 | 8.70e-01 |
| Downstream signaling of activated FGFR4 | 17 | 7.37e-01 | 0.047000 | 8.25e-01 |
| Viral Messenger RNA Synthesis | 44 | 5.90e-01 | -0.046900 | 7.14e-01 |
| Signaling by ERBB2 ECD mutants | 15 | 7.58e-01 | 0.045900 | 8.42e-01 |
| Synthesis of PC | 23 | 7.06e-01 | 0.045500 | 8.03e-01 |
| Acyl chain remodelling of PS | 14 | 7.71e-01 | -0.044900 | 8.50e-01 |
| Antigen processing: Ubiquitination & Proteasome degradation | 288 | 1.93e-01 | -0.044600 | 3.26e-01 |
| Formation of Incision Complex in GG-NER | 43 | 6.14e-01 | 0.044500 | 7.32e-01 |
| Cytochrome P450 - arranged by substrate type | 36 | 6.45e-01 | -0.044400 | 7.57e-01 |
| Signaling by FGFR in disease | 51 | 5.96e-01 | -0.042900 | 7.17e-01 |
| Late Phase of HIV Life Cycle | 131 | 3.99e-01 | -0.042600 | 5.49e-01 |
| Activation of RAC1 | 11 | 8.08e-01 | -0.042300 | 8.79e-01 |
| NOTCH2 intracellular domain regulates transcription | 11 | 8.09e-01 | -0.042200 | 8.79e-01 |
| Organelle biogenesis and maintenance | 270 | 2.33e-01 | -0.042200 | 3.72e-01 |
| TP53 Regulates Transcription of Cell Death Genes | 43 | 6.33e-01 | -0.042100 | 7.49e-01 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | 14 | 7.85e-01 | 0.042100 | 8.62e-01 |
| COPI-dependent Golgi-to-ER retrograde traffic | 78 | 5.28e-01 | -0.041300 | 6.59e-01 |
| Regulation of HSF1-mediated heat shock response | 79 | 5.27e-01 | -0.041100 | 6.58e-01 |
| Activation of gene expression by SREBF (SREBP) | 42 | 6.46e-01 | -0.041000 | 7.57e-01 |
| ATF4 activates genes in response to endoplasmic reticulum stress | 26 | 7.18e-01 | 0.040900 | 8.13e-01 |
| VxPx cargo-targeting to cilium | 19 | 7.59e-01 | 0.040700 | 8.42e-01 |
| Signalling to RAS | 18 | 7.66e-01 | -0.040500 | 8.47e-01 |
| Transcription of the HIV genome | 67 | 5.68e-01 | -0.040300 | 6.97e-01 |
| Cargo concentration in the ER | 30 | 7.08e-01 | -0.039500 | 8.04e-01 |
| Acyl chain remodelling of PG | 11 | 8.21e-01 | -0.039400 | 8.87e-01 |
| Glyoxylate metabolism and glycine degradation | 24 | 7.40e-01 | 0.039200 | 8.27e-01 |
| Transcriptional Regulation by VENTX | 38 | 6.80e-01 | -0.038700 | 7.85e-01 |
| Synthesis of DNA | 119 | 4.67e-01 | -0.038600 | 6.13e-01 |
| Mitotic Prophase | 98 | 5.12e-01 | -0.038300 | 6.45e-01 |
| Ca2+ pathway | 57 | 6.18e-01 | -0.038200 | 7.36e-01 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | 36 | 6.94e-01 | 0.037900 | 7.95e-01 |
| Diseases of mitotic cell cycle | 36 | 6.94e-01 | 0.037900 | 7.95e-01 |
| TNFR1-induced proapoptotic signaling | 12 | 8.25e-01 | -0.037000 | 8.87e-01 |
| HCMV Early Events | 74 | 5.83e-01 | -0.036900 | 7.09e-01 |
| CLEC7A (Dectin-1) induces NFAT activation | 11 | 8.32e-01 | -0.036900 | 8.90e-01 |
| Formation of apoptosome | 11 | 8.32e-01 | -0.036900 | 8.90e-01 |
| Regulation of the apoptosome activity | 11 | 8.32e-01 | -0.036900 | 8.90e-01 |
| Interleukin-20 family signaling | 17 | 7.94e-01 | -0.036600 | 8.68e-01 |
| RAF activation | 32 | 7.21e-01 | 0.036500 | 8.13e-01 |
| G beta:gamma signalling through BTK | 15 | 8.07e-01 | -0.036500 | 8.79e-01 |
| SUMOylation of transcription factors | 16 | 8.02e-01 | -0.036200 | 8.75e-01 |
| SUMOylation of RNA binding proteins | 47 | 6.80e-01 | 0.034800 | 7.85e-01 |
| Factors involved in megakaryocyte development and platelet production | 116 | 5.18e-01 | -0.034800 | 6.50e-01 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | 14 | 8.24e-01 | -0.034300 | 8.87e-01 |
| Lagging Strand Synthesis | 20 | 7.92e-01 | 0.034000 | 8.67e-01 |
| Post-translational modification: synthesis of GPI-anchored proteins | 58 | 6.56e-01 | -0.033800 | 7.67e-01 |
| ATF6 (ATF6-alpha) activates chaperone genes | 10 | 8.55e-01 | 0.033400 | 9.06e-01 |
| TNFR1-induced NFkappaB signaling pathway | 25 | 7.72e-01 | 0.033400 | 8.50e-01 |
| Cell Cycle | 624 | 1.55e-01 | 0.033300 | 2.77e-01 |
| RHO GTPases activate CIT | 18 | 8.09e-01 | -0.033000 | 8.79e-01 |
| Metabolism of vitamins and cofactors | 158 | 4.77e-01 | -0.032800 | 6.22e-01 |
| FGFR1 mutant receptor activation | 24 | 7.84e-01 | 0.032300 | 8.61e-01 |
| Diseases associated with N-glycosylation of proteins | 17 | 8.23e-01 | -0.031400 | 8.87e-01 |
| Generic Transcription Pathway | 1087 | 8.19e-02 | -0.031200 | 1.72e-01 |
| Scavenging by Class A Receptors | 12 | 8.52e-01 | -0.031200 | 9.04e-01 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | 17 | 8.25e-01 | 0.031000 | 8.87e-01 |
| Apoptosis induced DNA fragmentation | 10 | 8.67e-01 | -0.030700 | 9.14e-01 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | 21 | 8.10e-01 | 0.030300 | 8.79e-01 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | 21 | 8.10e-01 | 0.030300 | 8.79e-01 |
| Neurotransmitter release cycle | 37 | 7.51e-01 | -0.030200 | 8.37e-01 |
| PI-3K cascade:FGFR1 | 12 | 8.58e-01 | 0.029900 | 9.08e-01 |
| MET activates PTK2 signaling | 15 | 8.45e-01 | 0.029200 | 9.00e-01 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | 55 | 7.08e-01 | 0.029200 | 8.04e-01 |
| Constitutive Signaling by EGFRvIII | 14 | 8.50e-01 | 0.029200 | 9.03e-01 |
| Signaling by EGFRvIII in Cancer | 14 | 8.50e-01 | 0.029200 | 9.03e-01 |
| RHO GTPases Activate ROCKs | 18 | 8.31e-01 | -0.029000 | 8.90e-01 |
| Downstream signal transduction | 27 | 7.94e-01 | -0.029000 | 8.68e-01 |
| Ovarian tumor domain proteases | 37 | 7.61e-01 | -0.028900 | 8.42e-01 |
| Dual Incision in GG-NER | 41 | 7.49e-01 | -0.028800 | 8.37e-01 |
| Sphingolipid de novo biosynthesis | 41 | 7.50e-01 | -0.028700 | 8.37e-01 |
| GABA receptor activation | 36 | 7.71e-01 | -0.028100 | 8.50e-01 |
| RNA Polymerase II Pre-transcription Events | 78 | 6.79e-01 | -0.027100 | 7.85e-01 |
| Constitutive Signaling by Overexpressed ERBB2 | 11 | 8.77e-01 | 0.027000 | 9.19e-01 |
| Deposition of new CENPA-containing nucleosomes at the centromere | 40 | 7.72e-01 | -0.026500 | 8.50e-01 |
| Nucleosome assembly | 40 | 7.72e-01 | -0.026500 | 8.50e-01 |
| Trafficking and processing of endosomal TLR | 13 | 8.69e-01 | -0.026400 | 9.16e-01 |
| AURKA Activation by TPX2 | 72 | 7.00e-01 | 0.026200 | 7.99e-01 |
| Golgi Cisternae Pericentriolar Stack Reorganization | 14 | 8.67e-01 | 0.025800 | 9.14e-01 |
| Ub-specific processing proteases | 171 | 5.69e-01 | -0.025200 | 6.98e-01 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | 72 | 7.15e-01 | 0.024900 | 8.09e-01 |
| Transport of Mature Transcript to Cytoplasm | 81 | 7.07e-01 | 0.024100 | 8.04e-01 |
| FCERI mediated NF-kB activation | 138 | 6.32e-01 | 0.023600 | 7.49e-01 |
| Glutathione conjugation | 26 | 8.35e-01 | -0.023600 | 8.93e-01 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | 14 | 8.79e-01 | 0.023400 | 9.21e-01 |
| Regulation of PLK1 Activity at G2/M Transition | 87 | 7.06e-01 | 0.023400 | 8.03e-01 |
| Synthesis of PA | 32 | 8.19e-01 | -0.023400 | 8.86e-01 |
| Ras activation upon Ca2+ influx through NMDA receptor | 16 | 8.72e-01 | -0.023300 | 9.17e-01 |
| Cell Cycle, Mitotic | 502 | 3.79e-01 | 0.022900 | 5.29e-01 |
| DNA strand elongation | 32 | 8.23e-01 | 0.022900 | 8.87e-01 |
| Growth hormone receptor signaling | 20 | 8.60e-01 | -0.022800 | 9.10e-01 |
| Peptide hormone metabolism | 49 | 7.85e-01 | -0.022500 | 8.62e-01 |
| BBSome-mediated cargo-targeting to cilium | 22 | 8.55e-01 | 0.022400 | 9.07e-01 |
| Triglyceride metabolism | 25 | 8.48e-01 | 0.022200 | 9.02e-01 |
| RNA Polymerase II Transcription | 1206 | 2.18e-01 | -0.021100 | 3.54e-01 |
| Mitotic Metaphase and Anaphase | 225 | 5.88e-01 | 0.020900 | 7.14e-01 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | 20 | 8.72e-01 | 0.020800 | 9.17e-01 |
| NCAM signaling for neurite out-growth | 43 | 8.17e-01 | -0.020400 | 8.86e-01 |
| Phase 4 - resting membrane potential | 10 | 9.13e-01 | 0.020100 | 9.49e-01 |
| Apoptotic execution phase | 45 | 8.18e-01 | -0.019800 | 8.86e-01 |
| G1/S Transition | 130 | 6.98e-01 | -0.019700 | 7.97e-01 |
| NCAM1 interactions | 23 | 8.71e-01 | 0.019600 | 9.17e-01 |
| Metabolism of steroids | 119 | 7.14e-01 | 0.019500 | 8.09e-01 |
| S Phase | 161 | 6.71e-01 | -0.019400 | 7.78e-01 |
| Metabolism of cofactors | 19 | 8.84e-01 | 0.019300 | 9.24e-01 |
| Regulation of TP53 Activity | 153 | 6.80e-01 | -0.019300 | 7.85e-01 |
| Gene expression (Transcription) | 1337 | 2.47e-01 | -0.018800 | 3.87e-01 |
| Loss of Nlp from mitotic centrosomes | 69 | 7.89e-01 | 0.018600 | 8.65e-01 |
| Loss of proteins required for interphase microtubule organization from the centrosome | 69 | 7.89e-01 | 0.018600 | 8.65e-01 |
| Tie2 Signaling | 16 | 8.98e-01 | -0.018400 | 9.36e-01 |
| DNA Replication | 126 | 7.21e-01 | -0.018400 | 8.13e-01 |
| Cilium Assembly | 181 | 6.71e-01 | 0.018300 | 7.78e-01 |
| Cargo trafficking to the periciliary membrane | 47 | 8.31e-01 | 0.018000 | 8.90e-01 |
| Nonhomologous End-Joining (NHEJ) | 42 | 8.44e-01 | 0.017500 | 9.00e-01 |
| TP53 Regulates Transcription of Cell Cycle Genes | 47 | 8.37e-01 | 0.017300 | 8.94e-01 |
| Apoptotic cleavage of cellular proteins | 34 | 8.63e-01 | -0.017100 | 9.13e-01 |
| Mitotic Anaphase | 224 | 6.67e-01 | 0.016700 | 7.76e-01 |
| Class I peroxisomal membrane protein import | 20 | 9.00e-01 | 0.016200 | 9.37e-01 |
| Diseases of DNA repair | 10 | 9.30e-01 | -0.016000 | 9.59e-01 |
| Interleukin-35 Signalling | 12 | 9.24e-01 | 0.015900 | 9.55e-01 |
| Anti-inflammatory response favouring Leishmania parasite infection | 170 | 7.22e-01 | -0.015800 | 8.13e-01 |
| Leishmania parasite growth and survival | 170 | 7.22e-01 | -0.015800 | 8.13e-01 |
| Phase II - Conjugation of compounds | 67 | 8.26e-01 | 0.015500 | 8.88e-01 |
| Potassium Channels | 66 | 8.31e-01 | -0.015200 | 8.90e-01 |
| Fcgamma receptor (FCGR) dependent phagocytosis | 147 | 7.51e-01 | 0.015200 | 8.37e-01 |
| Processive synthesis on the lagging strand | 15 | 9.20e-01 | -0.015000 | 9.52e-01 |
| Recruitment of NuMA to mitotic centrosomes | 80 | 8.18e-01 | -0.014900 | 8.86e-01 |
| Fc epsilon receptor (FCERI) signaling | 191 | 7.27e-01 | -0.014700 | 8.15e-01 |
| Transcription of E2F targets under negative control by DREAM complex | 19 | 9.14e-01 | -0.014300 | 9.49e-01 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | 49 | 8.65e-01 | 0.014100 | 9.13e-01 |
| TICAM1, RIP1-mediated IKK complex recruitment | 19 | 9.17e-01 | -0.013800 | 9.50e-01 |
| Termination of translesion DNA synthesis | 32 | 8.94e-01 | 0.013600 | 9.32e-01 |
| Inactivation, recovery and regulation of the phototransduction cascade | 25 | 9.07e-01 | 0.013500 | 9.44e-01 |
| Signaling by BMP | 21 | 9.17e-01 | -0.013200 | 9.50e-01 |
| Reproduction | 81 | 8.39e-01 | -0.013000 | 8.96e-01 |
| PKMTs methylate histone lysines | 45 | 8.85e-01 | 0.012400 | 9.24e-01 |
| ATF6 (ATF6-alpha) activates chaperones | 12 | 9.42e-01 | 0.012100 | 9.69e-01 |
| Mitotic G1 phase and G1/S transition | 148 | 7.99e-01 | -0.012100 | 8.72e-01 |
| Nicotinate metabolism | 26 | 9.15e-01 | 0.012100 | 9.49e-01 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | 25 | 9.25e-01 | 0.010900 | 9.55e-01 |
| Negative regulators of DDX58/IFIH1 signaling | 34 | 9.13e-01 | -0.010800 | 9.49e-01 |
| Signaling by NTRK2 (TRKB) | 20 | 9.34e-01 | -0.010600 | 9.63e-01 |
| SUMOylation of chromatin organization proteins | 57 | 8.90e-01 | 0.010600 | 9.29e-01 |
| Metabolism of water-soluble vitamins and cofactors | 112 | 8.47e-01 | 0.010500 | 9.02e-01 |
| Cardiac conduction | 93 | 8.65e-01 | -0.010200 | 9.13e-01 |
| Mitotic G2-G2/M phases | 182 | 8.22e-01 | 0.009690 | 8.87e-01 |
| Centrosome maturation | 81 | 8.83e-01 | -0.009460 | 9.24e-01 |
| Recruitment of mitotic centrosome proteins and complexes | 81 | 8.83e-01 | -0.009460 | 9.24e-01 |
| DNA Repair | 289 | 7.83e-01 | -0.009430 | 8.61e-01 |
| BMAL1:CLOCK,NPAS2 activates circadian gene expression | 25 | 9.38e-01 | -0.009050 | 9.65e-01 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | 16 | 9.52e-01 | -0.008610 | 9.77e-01 |
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | 17 | 9.52e-01 | 0.008420 | 9.77e-01 |
| G2/M Checkpoints | 139 | 8.74e-01 | 0.007790 | 9.17e-01 |
| Peroxisomal lipid metabolism | 27 | 9.47e-01 | -0.007440 | 9.72e-01 |
| Biotin transport and metabolism | 11 | 9.66e-01 | -0.007420 | 9.86e-01 |
| HuR (ELAVL1) binds and stabilizes mRNA | 10 | 9.68e-01 | -0.007220 | 9.87e-01 |
| Signaling by the B Cell Receptor (BCR) | 163 | 8.74e-01 | -0.007180 | 9.17e-01 |
| Depolymerisation of the Nuclear Lamina | 15 | 9.63e-01 | 0.006870 | 9.85e-01 |
| Meiosis | 68 | 9.26e-01 | 0.006530 | 9.55e-01 |
| Initiation of Nuclear Envelope (NE) Reformation | 19 | 9.61e-01 | -0.006480 | 9.85e-01 |
| G beta:gamma signalling through CDC42 | 17 | 9.64e-01 | 0.006360 | 9.85e-01 |
| Interleukin-6 family signaling | 19 | 9.63e-01 | -0.006210 | 9.85e-01 |
| Removal of the Flap Intermediate | 14 | 9.70e-01 | 0.005760 | 9.88e-01 |
| Deadenylation-dependent mRNA decay | 53 | 9.44e-01 | -0.005580 | 9.70e-01 |
| Regulation of IFNA signaling | 12 | 9.74e-01 | 0.005400 | 9.89e-01 |
| Mismatch Repair | 15 | 9.72e-01 | -0.005190 | 9.88e-01 |
| WNT ligand biogenesis and trafficking | 21 | 9.71e-01 | 0.004500 | 9.88e-01 |
| MET promotes cell motility | 26 | 9.69e-01 | 0.004470 | 9.87e-01 |
| G2/M Transition | 180 | 9.21e-01 | 0.004290 | 9.52e-01 |
| Kinesins | 39 | 9.63e-01 | 0.004260 | 9.85e-01 |
| Unwinding of DNA | 12 | 9.80e-01 | 0.004250 | 9.92e-01 |
| Apoptotic factor-mediated response | 18 | 9.76e-01 | -0.004150 | 9.89e-01 |
| The phototransduction cascade | 26 | 9.73e-01 | 0.003870 | 9.88e-01 |
| SHC-mediated cascade:FGFR4 | 10 | 9.88e-01 | 0.002710 | 9.93e-01 |
| FRS-mediated FGFR4 signaling | 12 | 9.88e-01 | 0.002550 | 9.93e-01 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | 17 | 9.87e-01 | 0.002300 | 9.93e-01 |
| NOD1/2 Signaling Pathway | 32 | 9.85e-01 | 0.001940 | 9.92e-01 |
| Cyclin D associated events in G1 | 47 | 9.83e-01 | -0.001750 | 9.92e-01 |
| G1 Phase | 47 | 9.83e-01 | -0.001750 | 9.92e-01 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | 12 | 9.93e-01 | -0.001560 | 9.93e-01 |
| HIV Transcription Initiation | 45 | 9.86e-01 | -0.001550 | 9.92e-01 |
| RNA Polymerase II HIV Promoter Escape | 45 | 9.86e-01 | -0.001550 | 9.92e-01 |
| RNA Polymerase II Promoter Escape | 45 | 9.86e-01 | -0.001550 | 9.92e-01 |
| RNA Polymerase II Transcription Initiation | 45 | 9.86e-01 | -0.001550 | 9.92e-01 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | 45 | 9.86e-01 | -0.001550 | 9.92e-01 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | 45 | 9.86e-01 | -0.001550 | 9.92e-01 |
| Signaling by KIT in disease | 20 | 9.92e-01 | 0.001360 | 9.93e-01 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | 20 | 9.92e-01 | 0.001360 | 9.93e-01 |
| M Phase | 361 | 9.71e-01 | 0.001130 | 9.88e-01 |
| RNA Polymerase I Transcription Termination | 30 | 9.92e-01 | 0.001120 | 9.93e-01 |
| DNA Damage Bypass | 47 | 9.91e-01 | -0.000997 | 9.93e-01 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | 14 | 9.96e-01 | 0.000698 | 9.96e-01 |
Detailed Gene set reports
Peptide chain elongation
| 809 | |
|---|---|
| set | Peptide chain elongation |
| setSize | 88 |
| pANOVA | 6.99e-40 |
| s.dist | -0.814 |
| p.adjustANOVA | 3.18e-37 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| EEF2 | -9122 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| EEF2 | -9122 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| EEF1A1 | -8426 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| RPL28 | -5853 |
| RPL26L1 | -5693 |
| RPL23A | -5130 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| RPS3A | -4198 |
| RPL6 | -3572 |
| RPS26 | -480 |
| RPL22L1 | 543 |
| RPS4Y1 | 1781 |
| RPSA | 3639 |
| RPS27L | 10040 |
| RPL3L | 10975 |
Eukaryotic Translation Elongation
| 352 | |
|---|---|
| set | Eukaryotic Translation Elongation |
| setSize | 93 |
| pANOVA | 7.24e-42 |
| s.dist | -0.812 |
| p.adjustANOVA | 9.88e-39 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| EEF1G | -9190 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| EEF2 | -9122 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| EEF1B2 | -9074 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| EEF1G | -9190 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| EEF2 | -9122 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| EEF1B2 | -9074 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| EEF1D | -8925 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| EEF1A1 | -8426 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| RPL28 | -5853 |
| RPL26L1 | -5693 |
| EEF1A1P5 | -5509 |
| RPL23A | -5130 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| RPS3A | -4198 |
| RPL6 | -3572 |
| EEF1A2 | -1197 |
| RPS26 | -480 |
| RPL22L1 | 543 |
| RPS4Y1 | 1781 |
| RPSA | 3639 |
| RPS27L | 10040 |
| RPL3L | 10975 |
Viral mRNA Translation
| 1316 | |
|---|---|
| set | Viral mRNA Translation |
| setSize | 88 |
| pANOVA | 1.33e-37 |
| s.dist | -0.789 |
| p.adjustANOVA | 3.63e-35 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| RPL28 | -5853 |
| RPL26L1 | -5693 |
| RPL23A | -5130 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| RPS3A | -4198 |
| RPL6 | -3572 |
| RPS26 | -480 |
| RPL22L1 | 543 |
| GRSF1 | 1588 |
| RPS4Y1 | 1781 |
| RPSA | 3639 |
| DNAJC3 | 4700 |
| RPS27L | 10040 |
| RPL3L | 10975 |
Formation of a pool of free 40S subunits
| 394 | |
|---|---|
| set | Formation of a pool of free 40S subunits |
| setSize | 100 |
| pANOVA | 1.06e-40 |
| s.dist | -0.771 |
| p.adjustANOVA | 7.21e-38 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| EIF3C | -9136 |
| EIF3G | -9126 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| EIF3L | -9067 |
| RPL27 | -9063 |
| EIF3F | -9057 |
| RPL36AL | -9053 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| EIF3C | -9136 |
| EIF3G | -9126 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| EIF3L | -9067 |
| RPL27 | -9063 |
| EIF3F | -9057 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| EIF3I | -8600 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| EIF3B | -7859 |
| EIF3D | -7793 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| EIF3K | -7563 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| EIF3H | -6351 |
| RPL28 | -5853 |
| RPL26L1 | -5693 |
| RPL23A | -5130 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| RPS3A | -4198 |
| RPL6 | -3572 |
| EIF3A | -755 |
| RPS26 | -480 |
| RPL22L1 | 543 |
| EIF3E | 1449 |
| RPS4Y1 | 1781 |
| EIF1AX | 3467 |
| RPSA | 3639 |
| EIF3M | 3896 |
| EIF3J | 9402 |
| RPS27L | 10040 |
| RPL3L | 10975 |
Eukaryotic Translation Termination
| 354 | |
|---|---|
| set | Eukaryotic Translation Termination |
| setSize | 92 |
| pANOVA | 5.98e-37 |
| s.dist | -0.765 |
| p.adjustANOVA | 1.36e-34 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| TRMT112 | -8899 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| RPL21 | -7466 |
| APEH | -7398 |
| RPL5 | -7391 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| RPL28 | -5853 |
| RPL26L1 | -5693 |
| RPL23A | -5130 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| RPS3A | -4198 |
| RPL6 | -3572 |
| RPS26 | -480 |
| RPL22L1 | 543 |
| RPS4Y1 | 1781 |
| GSPT2 | 2014 |
| RPSA | 3639 |
| ETF1 | 4209 |
| N6AMT1 | 4374 |
| GSPT1 | 9073 |
| RPS27L | 10040 |
| RPL3L | 10975 |
Selenocysteine synthesis
| 1061 | |
|---|---|
| set | Selenocysteine synthesis |
| setSize | 92 |
| pANOVA | 2.25e-36 |
| s.dist | -0.758 |
| p.adjustANOVA | 3.57e-34 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| SARS1 | -7917 |
| RPS18 | -7912 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| RPL28 | -5853 |
| RPL26L1 | -5693 |
| RPL23A | -5130 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| SEPHS2 | -4755 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| RPS3A | -4198 |
| RPL6 | -3572 |
| EEFSEC | -2769 |
| RPS26 | -480 |
| RPL22L1 | 543 |
| RPS4Y1 | 1781 |
| RPSA | 3639 |
| PSTK | 3679 |
| RPS27L | 10040 |
| SEPSECS | 10464 |
| RPL3L | 10975 |
| SECISBP2 | 10990 |
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
| 745 | |
|---|---|
| set | Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) |
| setSize | 94 |
| pANOVA | 3.77e-34 |
| s.dist | -0.726 |
| p.adjustANOVA | 4.29e-32 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| EIF4G1 | -6857 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| RPL28 | -5853 |
| RPL26L1 | -5693 |
| RPL23A | -5130 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| RPS3A | -4198 |
| UPF1 | -3832 |
| RPL6 | -3572 |
| RPS26 | -480 |
| RPL22L1 | 543 |
| RPS4Y1 | 1781 |
| GSPT2 | 2014 |
| PABPC1 | 2767 |
| RPSA | 3639 |
| ETF1 | 4209 |
| GSPT1 | 9073 |
| RPS27L | 10040 |
| RPL3L | 10975 |
| NCBP2 | 11197 |
| NCBP1 | 11649 |
L13a-mediated translational silencing of Ceruloplasmin expression
| 590 | |
|---|---|
| set | L13a-mediated translational silencing of Ceruloplasmin expression |
| setSize | 110 |
| pANOVA | 1.1e-37 |
| s.dist | -0.707 |
| p.adjustANOVA | 3.63e-35 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| EIF4H | -9180 |
| RPL8 | -9153 |
| EIF3C | -9136 |
| EIF3G | -9126 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| EIF3L | -9067 |
| RPL27 | -9063 |
| EIF3F | -9057 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| EIF4H | -9180 |
| RPL8 | -9153 |
| EIF3C | -9136 |
| EIF3G | -9126 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| EIF3L | -9067 |
| RPL27 | -9063 |
| EIF3F | -9057 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| EIF3I | -8600 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| EIF3B | -7859 |
| EIF3D | -7793 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| EIF3K | -7563 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| EIF4B | -7365 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| EIF4G1 | -6857 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| EIF3H | -6351 |
| RPL28 | -5853 |
| RPL26L1 | -5693 |
| RPL23A | -5130 |
| EIF4A1 | -5084 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| RPS3A | -4198 |
| RPL6 | -3572 |
| EIF3A | -755 |
| RPS26 | -480 |
| RPL22L1 | 543 |
| EIF3E | 1449 |
| RPS4Y1 | 1781 |
| PABPC1 | 2767 |
| EIF1AX | 3467 |
| RPSA | 3639 |
| EIF3M | 3896 |
| EIF2S3 | 4258 |
| EIF2S1 | 7268 |
| EIF2S2 | 7376 |
| EIF4A2 | 7989 |
| EIF3J | 9402 |
| RPS27L | 10040 |
| EIF4E | 10302 |
| RPL3L | 10975 |
GTP hydrolysis and joining of the 60S ribosomal subunit
| 436 | |
|---|---|
| set | GTP hydrolysis and joining of the 60S ribosomal subunit |
| setSize | 111 |
| pANOVA | 2.36e-36 |
| s.dist | -0.691 |
| p.adjustANOVA | 3.57e-34 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| EIF4H | -9180 |
| RPL8 | -9153 |
| EIF3C | -9136 |
| EIF3G | -9126 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| EIF3L | -9067 |
| RPL27 | -9063 |
| EIF3F | -9057 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| EIF4H | -9180 |
| RPL8 | -9153 |
| EIF3C | -9136 |
| EIF3G | -9126 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| EIF3L | -9067 |
| RPL27 | -9063 |
| EIF3F | -9057 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| EIF3I | -8600 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| EIF3B | -7859 |
| EIF3D | -7793 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| EIF3K | -7563 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| EIF4B | -7365 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| EIF4G1 | -6857 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| EIF3H | -6351 |
| RPL28 | -5853 |
| RPL26L1 | -5693 |
| RPL23A | -5130 |
| EIF4A1 | -5084 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| RPS3A | -4198 |
| RPL6 | -3572 |
| EIF3A | -755 |
| RPS26 | -480 |
| RPL22L1 | 543 |
| EIF3E | 1449 |
| RPS4Y1 | 1781 |
| EIF1AX | 3467 |
| RPSA | 3639 |
| EIF3M | 3896 |
| EIF2S3 | 4258 |
| EIF2S1 | 7268 |
| EIF5 | 7300 |
| EIF2S2 | 7376 |
| EIF4A2 | 7989 |
| EIF5B | 9391 |
| EIF3J | 9402 |
| RPS27L | 10040 |
| EIF4E | 10302 |
| RPL3L | 10975 |
VLDLR internalisation and degradation
| 1311 | |
|---|---|
| set | VLDLR internalisation and degradation |
| setSize | 11 |
| pANOVA | 8.08e-05 |
| s.dist | -0.686 |
| p.adjustANOVA | 0.00088 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| AP2M1 | -9075 |
| NR1H3 | -8011 |
| AP2S1 | -7871 |
| NR1H2 | -7174 |
| MYLIP | -7031 |
| AP2A2 | -6809 |
| AP2A1 | -6392 |
| CLTA | -6017 |
| VLDLR | -2494 |
| CLTC | -1627 |
| AP2B1 | -1491 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| AP2M1 | -9075 |
| NR1H3 | -8011 |
| AP2S1 | -7871 |
| NR1H2 | -7174 |
| MYLIP | -7031 |
| AP2A2 | -6809 |
| AP2A1 | -6392 |
| CLTA | -6017 |
| VLDLR | -2494 |
| CLTC | -1627 |
| AP2B1 | -1491 |
Response of EIF2AK4 (GCN2) to amino acid deficiency
| 1009 | |
|---|---|
| set | Response of EIF2AK4 (GCN2) to amino acid deficiency |
| setSize | 100 |
| pANOVA | 6.51e-31 |
| s.dist | -0.668 |
| p.adjustANOVA | 6.35e-29 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| EIF2AK4 | -6881 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| RPL28 | -5853 |
| ATF4 | -5749 |
| RPL26L1 | -5693 |
| RPL23A | -5130 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| RPS3A | -4198 |
| RPL6 | -3572 |
| CEBPB | -2858 |
| RPS26 | -480 |
| GCN1 | -373 |
| RPL22L1 | 543 |
| RPS4Y1 | 1781 |
| RPSA | 3639 |
| EIF2S3 | 4258 |
| TRIB3 | 4873 |
| DDIT3 | 6097 |
| CEBPG | 6319 |
| ASNS | 7110 |
| EIF2S1 | 7268 |
| EIF2S2 | 7376 |
| IMPACT | 9271 |
| ATF2 | 9744 |
| RPS27L | 10040 |
| ATF3 | 10415 |
| RPL3L | 10975 |
Cap-dependent Translation Initiation
| 145 | |
|---|---|
| set | Cap-dependent Translation Initiation |
| setSize | 118 |
| pANOVA | 9.58e-36 |
| s.dist | -0.664 |
| p.adjustANOVA | 1.19e-33 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| EIF4H | -9180 |
| RPL8 | -9153 |
| EIF3C | -9136 |
| EIF3G | -9126 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| EIF3L | -9067 |
| RPL27 | -9063 |
| EIF3F | -9057 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| EIF4H | -9180 |
| RPL8 | -9153 |
| EIF3C | -9136 |
| EIF3G | -9126 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| EIF3L | -9067 |
| RPL27 | -9063 |
| EIF3F | -9057 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| EIF3I | -8600 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| EIF3B | -7859 |
| EIF3D | -7793 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| EIF3K | -7563 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| EIF4B | -7365 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| EIF4G1 | -6857 |
| EIF4EBP1 | -6698 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| EIF3H | -6351 |
| EIF2B4 | -5895 |
| RPL28 | -5853 |
| RPL26L1 | -5693 |
| RPL23A | -5130 |
| EIF4A1 | -5084 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| EIF2B2 | -4801 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| RPS3A | -4198 |
| RPL6 | -3572 |
| EIF2B5 | -837 |
| EIF3A | -755 |
| RPS26 | -480 |
| RPL22L1 | 543 |
| EIF3E | 1449 |
| RPS4Y1 | 1781 |
| PABPC1 | 2767 |
| EIF1AX | 3467 |
| EIF2B3 | 3486 |
| RPSA | 3639 |
| EIF3M | 3896 |
| EIF2S3 | 4258 |
| EIF2B1 | 5965 |
| EIF2S1 | 7268 |
| EIF5 | 7300 |
| EIF2S2 | 7376 |
| EIF4A2 | 7989 |
| EIF5B | 9391 |
| EIF3J | 9402 |
| RPS27L | 10040 |
| EIF4E | 10302 |
| RPL3L | 10975 |
Eukaryotic Translation Initiation
| 353 | |
|---|---|
| set | Eukaryotic Translation Initiation |
| setSize | 118 |
| pANOVA | 9.58e-36 |
| s.dist | -0.664 |
| p.adjustANOVA | 1.19e-33 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| EIF4H | -9180 |
| RPL8 | -9153 |
| EIF3C | -9136 |
| EIF3G | -9126 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| EIF3L | -9067 |
| RPL27 | -9063 |
| EIF3F | -9057 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| EIF4H | -9180 |
| RPL8 | -9153 |
| EIF3C | -9136 |
| EIF3G | -9126 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| EIF3L | -9067 |
| RPL27 | -9063 |
| EIF3F | -9057 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| EIF3I | -8600 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| EIF3B | -7859 |
| EIF3D | -7793 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| EIF3K | -7563 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| EIF4B | -7365 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| EIF4G1 | -6857 |
| EIF4EBP1 | -6698 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| EIF3H | -6351 |
| EIF2B4 | -5895 |
| RPL28 | -5853 |
| RPL26L1 | -5693 |
| RPL23A | -5130 |
| EIF4A1 | -5084 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| EIF2B2 | -4801 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| RPS3A | -4198 |
| RPL6 | -3572 |
| EIF2B5 | -837 |
| EIF3A | -755 |
| RPS26 | -480 |
| RPL22L1 | 543 |
| EIF3E | 1449 |
| RPS4Y1 | 1781 |
| PABPC1 | 2767 |
| EIF1AX | 3467 |
| EIF2B3 | 3486 |
| RPSA | 3639 |
| EIF3M | 3896 |
| EIF2S3 | 4258 |
| EIF2B1 | 5965 |
| EIF2S1 | 7268 |
| EIF5 | 7300 |
| EIF2S2 | 7376 |
| EIF4A2 | 7989 |
| EIF5B | 9391 |
| EIF3J | 9402 |
| RPS27L | 10040 |
| EIF4E | 10302 |
| RPL3L | 10975 |
Formation of the ternary complex, and subsequently, the 43S complex
| 400 | |
|---|---|
| set | Formation of the ternary complex, and subsequently, the 43S complex |
| setSize | 51 |
| pANOVA | 3.04e-15 |
| s.dist | -0.638 |
| p.adjustANOVA | 1.01e-13 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPS29 | -9213 |
| RPS17 | -9182 |
| EIF3C | -9136 |
| EIF3G | -9126 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPS10 | -9077 |
| EIF3L | -9067 |
| EIF3F | -9057 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPS27 | -8945 |
| RPS27A | -8920 |
| RPS14 | -8888 |
| RPS28 | -8811 |
| RPS19 | -8708 |
| RPS9 | -8681 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPS29 | -9213 |
| RPS17 | -9182 |
| EIF3C | -9136 |
| EIF3G | -9126 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPS10 | -9077 |
| EIF3L | -9067 |
| EIF3F | -9057 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPS27 | -8945 |
| RPS27A | -8920 |
| RPS14 | -8888 |
| RPS28 | -8811 |
| RPS19 | -8708 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| EIF3I | -8600 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| EIF3B | -7859 |
| EIF3D | -7793 |
| EIF3K | -7563 |
| RPS8 | -6940 |
| RPS20 | -6373 |
| EIF3H | -6351 |
| RPS4X | -4837 |
| RPS24 | -4741 |
| RPS3A | -4198 |
| EIF3A | -755 |
| RPS26 | -480 |
| EIF3E | 1449 |
| RPS4Y1 | 1781 |
| EIF1AX | 3467 |
| RPSA | 3639 |
| EIF3M | 3896 |
| EIF2S3 | 4258 |
| EIF2S1 | 7268 |
| EIF2S2 | 7376 |
| EIF3J | 9402 |
| RPS27L | 10040 |
Josephin domain DUBs
| 584 | |
|---|---|
| set | Josephin domain DUBs |
| setSize | 10 |
| pANOVA | 0.000553 |
| s.dist | -0.631 |
| p.adjustANOVA | 0.00429 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| JOSD2 | -8742 |
| UBA52 | -8454 |
| VCP | -7569 |
| UBB | -6926 |
| RAD23A | -5423 |
| RAD23B | -4960 |
| JOSD1 | -4469 |
| UBC | -4156 |
| ATXN3 | 7591 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| JOSD2 | -8742 |
| UBA52 | -8454 |
| VCP | -7569 |
| UBB | -6926 |
| RAD23A | -5423 |
| RAD23B | -4960 |
| JOSD1 | -4469 |
| UBC | -4156 |
| ATXN3 | 7591 |
SRP-dependent cotranslational protein targeting to membrane
| 1041 | |
|---|---|
| set | SRP-dependent cotranslational protein targeting to membrane |
| setSize | 111 |
| pANOVA | 7.47e-30 |
| s.dist | -0.623 |
| p.adjustANOVA | 6.8e-28 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| DDOST | -9015 |
| RPL7A | -9005 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| DDOST | -9015 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| SEC61B | -8197 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| RPN1 | -7000 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| SSR4 | -6919 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| RPL28 | -5853 |
| RPL26L1 | -5693 |
| SSR2 | -5309 |
| RPL23A | -5130 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| RPS3A | -4198 |
| SRPRA | -4080 |
| RPL6 | -3572 |
| SEC11A | -2918 |
| SEC61A1 | -2702 |
| SPCS1 | -2314 |
| RPN2 | -1452 |
| RPS26 | -480 |
| SRP68 | -313 |
| RPL22L1 | 543 |
| SRP14 | 1030 |
| RPS4Y1 | 1781 |
| SSR1 | 2012 |
| RPSA | 3639 |
| SRPRB | 4476 |
| SRP72 | 5294 |
| SRP9 | 5411 |
| SSR3 | 5855 |
| SPCS2 | 7536 |
| TRAM1 | 8019 |
| SEC61A2 | 8059 |
| SEC61G | 8733 |
| SPCS3 | 9898 |
| RPS27L | 10040 |
| RPL3L | 10975 |
| SEC11C | 10982 |
| SRP19 | 11789 |
| SRP54 | 12390 |
Formation of ATP by chemiosmotic coupling
| 386 | |
|---|---|
| set | Formation of ATP by chemiosmotic coupling |
| setSize | 18 |
| pANOVA | 7.32e-06 |
| s.dist | -0.61 |
| p.adjustANOVA | 0.000122 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MT-ATP8 | -9237 |
| ATP5ME | -9114 |
| ATP5MG | -9055 |
| ATP5F1D | -8993 |
| ATP5MF | -8988 |
| ATP5MC2 | -8655 |
| MT-ATP6 | -8247 |
| ATP5F1E | -7305 |
| ATP5F1A | -7191 |
| ATP5MC3 | -6943 |
| ATP5PB | -5586 |
| ATP5F1B | -4642 |
| ATP5PF | -4410 |
| ATP5PO | -2733 |
| ATP5MC1 | -1306 |
| ATP5PD | -1292 |
| ATP5F1C | 2542 |
| DMAC2L | 11593 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MT-ATP8 | -9237 |
| ATP5ME | -9114 |
| ATP5MG | -9055 |
| ATP5F1D | -8993 |
| ATP5MF | -8988 |
| ATP5MC2 | -8655 |
| MT-ATP6 | -8247 |
| ATP5F1E | -7305 |
| ATP5F1A | -7191 |
| ATP5MC3 | -6943 |
| ATP5PB | -5586 |
| ATP5F1B | -4642 |
| ATP5PF | -4410 |
| ATP5PO | -2733 |
| ATP5MC1 | -1306 |
| ATP5PD | -1292 |
| ATP5F1C | 2542 |
| DMAC2L | 11593 |
WNT5A-dependent internalization of FZD4
| 1326 | |
|---|---|
| set | WNT5A-dependent internalization of FZD4 |
| setSize | 13 |
| pANOVA | 0.000151 |
| s.dist | -0.607 |
| p.adjustANOVA | 0.00148 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| AP2M1 | -9075 |
| CLTB | -8898 |
| AP2S1 | -7871 |
| ARRB2 | -7822 |
| AP2A2 | -6809 |
| AP2A1 | -6392 |
| DVL2 | -6297 |
| CLTA | -6017 |
| PRKCB | -4714 |
| PRKCA | -4463 |
| CLTC | -1627 |
| AP2B1 | -1491 |
| FZD4 | 7261 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| AP2M1 | -9075 |
| CLTB | -8898 |
| AP2S1 | -7871 |
| ARRB2 | -7822 |
| AP2A2 | -6809 |
| AP2A1 | -6392 |
| DVL2 | -6297 |
| CLTA | -6017 |
| PRKCB | -4714 |
| PRKCA | -4463 |
| CLTC | -1627 |
| AP2B1 | -1491 |
| FZD4 | 7261 |
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
| 744 | |
|---|---|
| set | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
| setSize | 114 |
| pANOVA | 1.58e-28 |
| s.dist | -0.6 |
| p.adjustANOVA | 1.27e-26 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| MAGOH | -9181 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| MAGOH | -9181 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| PPP2R1A | -8177 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| SMG5 | -7683 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| EIF4A3 | -7329 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| EIF4G1 | -6857 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| RPL28 | -5853 |
| RPL26L1 | -5693 |
| RPL23A | -5130 |
| RBM8A | -4969 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| RPS3A | -4198 |
| UPF1 | -3832 |
| RNPS1 | -3636 |
| RPL6 | -3572 |
| SMG6 | -2610 |
| CASC3 | -2260 |
| UPF3A | -1277 |
| RPS26 | -480 |
| PPP2CA | -317 |
| SMG9 | 505 |
| RPL22L1 | 543 |
| RPS4Y1 | 1781 |
| GSPT2 | 2014 |
| PABPC1 | 2767 |
| RPSA | 3639 |
| ETF1 | 4209 |
| SMG8 | 6619 |
| UPF3B | 7058 |
| SMG1 | 7389 |
| MAGOHB | 7470 |
| SMG7 | 7650 |
| GSPT1 | 9073 |
| RPS27L | 10040 |
| DCP1A | 10181 |
| UPF2 | 10733 |
| RPL3L | 10975 |
| NCBP2 | 11197 |
| NCBP1 | 11649 |
| PNRC2 | 11688 |
| PPP2R2A | 12626 |
Nonsense-Mediated Decay (NMD)
| 746 | |
|---|---|
| set | Nonsense-Mediated Decay (NMD) |
| setSize | 114 |
| pANOVA | 1.58e-28 |
| s.dist | -0.6 |
| p.adjustANOVA | 1.27e-26 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| MAGOH | -9181 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| MAGOH | -9181 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| PPP2R1A | -8177 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| SMG5 | -7683 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| EIF4A3 | -7329 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| EIF4G1 | -6857 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| RPL28 | -5853 |
| RPL26L1 | -5693 |
| RPL23A | -5130 |
| RBM8A | -4969 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| RPS3A | -4198 |
| UPF1 | -3832 |
| RNPS1 | -3636 |
| RPL6 | -3572 |
| SMG6 | -2610 |
| CASC3 | -2260 |
| UPF3A | -1277 |
| RPS26 | -480 |
| PPP2CA | -317 |
| SMG9 | 505 |
| RPL22L1 | 543 |
| RPS4Y1 | 1781 |
| GSPT2 | 2014 |
| PABPC1 | 2767 |
| RPSA | 3639 |
| ETF1 | 4209 |
| SMG8 | 6619 |
| UPF3B | 7058 |
| SMG1 | 7389 |
| MAGOHB | 7470 |
| SMG7 | 7650 |
| GSPT1 | 9073 |
| RPS27L | 10040 |
| DCP1A | 10181 |
| UPF2 | 10733 |
| RPL3L | 10975 |
| NCBP2 | 11197 |
| NCBP1 | 11649 |
| PNRC2 | 11688 |
| PPP2R2A | 12626 |
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
| 50 | |
|---|---|
| set | Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| setSize | 59 |
| pANOVA | 2.49e-15 |
| s.dist | -0.595 |
| p.adjustANOVA | 8.5e-14 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPS29 | -9213 |
| RPS17 | -9182 |
| EIF4H | -9180 |
| EIF3C | -9136 |
| EIF3G | -9126 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPS10 | -9077 |
| EIF3L | -9067 |
| EIF3F | -9057 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPS27 | -8945 |
| RPS27A | -8920 |
| RPS14 | -8888 |
| RPS28 | -8811 |
| RPS19 | -8708 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPS29 | -9213 |
| RPS17 | -9182 |
| EIF4H | -9180 |
| EIF3C | -9136 |
| EIF3G | -9126 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPS10 | -9077 |
| EIF3L | -9067 |
| EIF3F | -9057 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPS27 | -8945 |
| RPS27A | -8920 |
| RPS14 | -8888 |
| RPS28 | -8811 |
| RPS19 | -8708 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| EIF3I | -8600 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| EIF3B | -7859 |
| EIF3D | -7793 |
| EIF3K | -7563 |
| EIF4B | -7365 |
| RPS8 | -6940 |
| EIF4G1 | -6857 |
| EIF4EBP1 | -6698 |
| RPS20 | -6373 |
| EIF3H | -6351 |
| EIF4A1 | -5084 |
| RPS4X | -4837 |
| RPS24 | -4741 |
| RPS3A | -4198 |
| EIF3A | -755 |
| RPS26 | -480 |
| EIF3E | 1449 |
| RPS4Y1 | 1781 |
| PABPC1 | 2767 |
| EIF1AX | 3467 |
| RPSA | 3639 |
| EIF3M | 3896 |
| EIF2S3 | 4258 |
| EIF2S1 | 7268 |
| EIF2S2 | 7376 |
| EIF4A2 | 7989 |
| EIF3J | 9402 |
| RPS27L | 10040 |
| EIF4E | 10302 |
Translation initiation complex formation
| 1270 | |
|---|---|
| set | Translation initiation complex formation |
| setSize | 58 |
| pANOVA | 5.85e-15 |
| s.dist | -0.592 |
| p.adjustANOVA | 1.9e-13 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPS29 | -9213 |
| RPS17 | -9182 |
| EIF4H | -9180 |
| EIF3C | -9136 |
| EIF3G | -9126 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPS10 | -9077 |
| EIF3L | -9067 |
| EIF3F | -9057 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPS27 | -8945 |
| RPS27A | -8920 |
| RPS14 | -8888 |
| RPS28 | -8811 |
| RPS19 | -8708 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPS29 | -9213 |
| RPS17 | -9182 |
| EIF4H | -9180 |
| EIF3C | -9136 |
| EIF3G | -9126 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPS10 | -9077 |
| EIF3L | -9067 |
| EIF3F | -9057 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPS27 | -8945 |
| RPS27A | -8920 |
| RPS14 | -8888 |
| RPS28 | -8811 |
| RPS19 | -8708 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| EIF3I | -8600 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| EIF3B | -7859 |
| EIF3D | -7793 |
| EIF3K | -7563 |
| EIF4B | -7365 |
| RPS8 | -6940 |
| EIF4G1 | -6857 |
| RPS20 | -6373 |
| EIF3H | -6351 |
| EIF4A1 | -5084 |
| RPS4X | -4837 |
| RPS24 | -4741 |
| RPS3A | -4198 |
| EIF3A | -755 |
| RPS26 | -480 |
| EIF3E | 1449 |
| RPS4Y1 | 1781 |
| PABPC1 | 2767 |
| EIF1AX | 3467 |
| RPSA | 3639 |
| EIF3M | 3896 |
| EIF2S3 | 4258 |
| EIF2S1 | 7268 |
| EIF2S2 | 7376 |
| EIF4A2 | 7989 |
| EIF3J | 9402 |
| RPS27L | 10040 |
| EIF4E | 10302 |
Ribosomal scanning and start codon recognition
| 1017 | |
|---|---|
| set | Ribosomal scanning and start codon recognition |
| setSize | 58 |
| pANOVA | 1.22e-14 |
| s.dist | -0.585 |
| p.adjustANOVA | 3.88e-13 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPS29 | -9213 |
| RPS17 | -9182 |
| EIF4H | -9180 |
| EIF3C | -9136 |
| EIF3G | -9126 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPS10 | -9077 |
| EIF3L | -9067 |
| EIF3F | -9057 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPS27 | -8945 |
| RPS27A | -8920 |
| RPS14 | -8888 |
| RPS28 | -8811 |
| RPS19 | -8708 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPS29 | -9213 |
| RPS17 | -9182 |
| EIF4H | -9180 |
| EIF3C | -9136 |
| EIF3G | -9126 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPS10 | -9077 |
| EIF3L | -9067 |
| EIF3F | -9057 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPS27 | -8945 |
| RPS27A | -8920 |
| RPS14 | -8888 |
| RPS28 | -8811 |
| RPS19 | -8708 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| EIF3I | -8600 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| EIF3B | -7859 |
| EIF3D | -7793 |
| EIF3K | -7563 |
| EIF4B | -7365 |
| RPS8 | -6940 |
| EIF4G1 | -6857 |
| RPS20 | -6373 |
| EIF3H | -6351 |
| EIF4A1 | -5084 |
| RPS4X | -4837 |
| RPS24 | -4741 |
| RPS3A | -4198 |
| EIF3A | -755 |
| RPS26 | -480 |
| EIF3E | 1449 |
| RPS4Y1 | 1781 |
| EIF1AX | 3467 |
| RPSA | 3639 |
| EIF3M | 3896 |
| EIF2S3 | 4258 |
| EIF2S1 | 7268 |
| EIF5 | 7300 |
| EIF2S2 | 7376 |
| EIF4A2 | 7989 |
| EIF3J | 9402 |
| RPS27L | 10040 |
| EIF4E | 10302 |
Selenoamino acid metabolism
| 1060 | |
|---|---|
| set | Selenoamino acid metabolism |
| setSize | 114 |
| pANOVA | 6.78e-27 |
| s.dist | -0.581 |
| p.adjustANOVA | 4.62e-25 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| QARS1 | -8783 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| RPS5 | -8589 |
| AHCY | -8570 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| SARS1 | -7917 |
| RPS18 | -7912 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| GSR | -6616 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| RPL28 | -5853 |
| RPL26L1 | -5693 |
| RPL23A | -5130 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| SEPHS2 | -4755 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| RPS3A | -4198 |
| RPL6 | -3572 |
| GNMT | -2777 |
| EEFSEC | -2769 |
| HNMT | -2739 |
| TXNRD1 | -2107 |
| SCLY | -1244 |
| AIMP2 | -1152 |
| RPS26 | -480 |
| RPL22L1 | 543 |
| PAPSS1 | 1076 |
| RPS4Y1 | 1781 |
| RPSA | 3639 |
| PSTK | 3679 |
| EEF1E1 | 4675 |
| KARS1 | 5471 |
| MARS1 | 5734 |
| EPRS1 | 6226 |
| IARS1 | 6774 |
| INMT | 7679 |
| DARS1 | 9060 |
| CTH | 9844 |
| RPS27L | 10040 |
| RARS1 | 10160 |
| SEPSECS | 10464 |
| AIMP1 | 10704 |
| RPL3L | 10975 |
| SECISBP2 | 10990 |
| LARS1 | 11104 |
| PAPSS2 | 11751 |
| CBS | 11892 |
Influenza Viral RNA Transcription and Replication
| 529 | |
|---|---|
| set | Influenza Viral RNA Transcription and Replication |
| setSize | 135 |
| pANOVA | 1.32e-26 |
| s.dist | -0.531 |
| p.adjustANOVA | 8.57e-25 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| POLR2L | -9269 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| POLR2E | -9009 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| POLR2L | -9269 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| POLR2E | -9009 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| POLR2F | -8657 |
| RPL18 | -8654 |
| POLR2G | -8638 |
| RPL39 | -8609 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| POLR2I | -8445 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| POLR2J | -8226 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| GTF2F1 | -7647 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| POLR2H | -7192 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| POM121C | -6837 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| SEC13 | -5867 |
| RPL28 | -5853 |
| RPL26L1 | -5693 |
| RPL23A | -5130 |
| POLR2C | -4979 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| NUP62 | -4381 |
| RPS3A | -4198 |
| NUP210 | -4025 |
| RPL6 | -3572 |
| POM121 | -3172 |
| NUP188 | -3159 |
| AAAS | -2187 |
| POLR2A | -1960 |
| IPO5 | -1656 |
| PARP1 | -1595 |
| RPS26 | -480 |
| NUP214 | -395 |
| GTF2F2 | 453 |
| RPL22L1 | 543 |
| NUP37 | 1467 |
| POLR2B | 1553 |
| GRSF1 | 1588 |
| RPS4Y1 | 1781 |
| NUP205 | 2600 |
| NUP98 | 2880 |
| NUP85 | 3065 |
| NDC1 | 3196 |
| NUP35 | 3316 |
| RPSA | 3639 |
| NUP133 | 4455 |
| RAE1 | 4630 |
| DNAJC3 | 4700 |
| NUP153 | 4974 |
| POLR2D | 5190 |
| NUP88 | 5983 |
| NUP58 | 6170 |
| NUP93 | 6656 |
| HSP90AA1 | 7453 |
| NUP160 | 7636 |
| NUP155 | 7756 |
| NUP50 | 7773 |
| POLR2K | 7850 |
| RANBP2 | 8025 |
| SEH1L | 8036 |
| TPR | 9075 |
| RPS27L | 10040 |
| NUP107 | 10450 |
| RPL3L | 10975 |
| NUP42 | 11590 |
| NUP43 | 11811 |
| NUP54 | 12575 |
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
| 1190 | |
|---|---|
| set | TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| setSize | 16 |
| pANOVA | 0.000249 |
| s.dist | -0.529 |
| p.adjustANOVA | 0.00216 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| PARD6A | -8628 |
| UBA52 | -8454 |
| TGFB1 | -7823 |
| TGFBR2 | -7585 |
| F11R | -7167 |
| UBB | -6926 |
| PRKCZ | -6281 |
| UBC | -4156 |
| ARHGEF18 | -2729 |
| FKBP1A | -1642 |
| PARD3 | -1605 |
| CGN | -1284 |
| RHOA | -387 |
| SMURF1 | 3334 |
| TGFBR1 | 5033 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| PARD6A | -8628 |
| UBA52 | -8454 |
| TGFB1 | -7823 |
| TGFBR2 | -7585 |
| F11R | -7167 |
| UBB | -6926 |
| PRKCZ | -6281 |
| UBC | -4156 |
| ARHGEF18 | -2729 |
| FKBP1A | -1642 |
| PARD3 | -1605 |
| CGN | -1284 |
| RHOA | -387 |
| SMURF1 | 3334 |
| TGFBR1 | 5033 |
NF-kB is activated and signals survival
| 699 | |
|---|---|
| set | NF-kB is activated and signals survival |
| setSize | 12 |
| pANOVA | 0.00151 |
| s.dist | -0.529 |
| p.adjustANOVA | 0.00939 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| SQSTM1 | -8744 |
| UBA52 | -8454 |
| NFKBIA | -8313 |
| IRAK1 | -7896 |
| RELA | -7350 |
| UBB | -6926 |
| UBC | -4156 |
| NFKB1 | -2798 |
| IKBKB | -167 |
| TRAF6 | 6905 |
| NGFR | 7911 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| SQSTM1 | -8744 |
| UBA52 | -8454 |
| NFKBIA | -8313 |
| IRAK1 | -7896 |
| RELA | -7350 |
| UBB | -6926 |
| UBC | -4156 |
| NFKB1 | -2798 |
| IKBKB | -167 |
| TRAF6 | 6905 |
| NGFR | 7911 |
Pexophagy
| 815 | |
|---|---|
| set | Pexophagy |
| setSize | 11 |
| pANOVA | 0.00277 |
| s.dist | -0.521 |
| p.adjustANOVA | 0.0149 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| SQSTM1 | -8744 |
| UBA52 | -8454 |
| USP30 | -6999 |
| UBB | -6926 |
| PEX5 | -4453 |
| UBC | -4156 |
| MAP1LC3B | -3351 |
| NBR1 | -2703 |
| ATM | 4076 |
| EPAS1 | 6752 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| SQSTM1 | -8744 |
| UBA52 | -8454 |
| USP30 | -6999 |
| UBB | -6926 |
| PEX5 | -4453 |
| UBC | -4156 |
| MAP1LC3B | -3351 |
| NBR1 | -2703 |
| ATM | 4076 |
| EPAS1 | 6752 |
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
| 1325 | |
|---|---|
| set | WNT5A-dependent internalization of FZD2, FZD5 and ROR2 |
| setSize | 11 |
| pANOVA | 0.00284 |
| s.dist | -0.52 |
| p.adjustANOVA | 0.0151 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| AP2M1 | -9075 |
| CLTB | -8898 |
| AP2S1 | -7871 |
| FZD2 | -7707 |
| AP2A2 | -6809 |
| AP2A1 | -6392 |
| CLTA | -6017 |
| CLTC | -1627 |
| AP2B1 | -1491 |
| FZD5 | 2845 |
| ROR1 | 9306 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| AP2M1 | -9075 |
| CLTB | -8898 |
| AP2S1 | -7871 |
| FZD2 | -7707 |
| AP2A2 | -6809 |
| AP2A1 | -6392 |
| CLTA | -6017 |
| CLTC | -1627 |
| AP2B1 | -1491 |
| FZD5 | 2845 |
| ROR1 | 9306 |
GP1b-IX-V activation signalling
| 429 | |
|---|---|
| set | GP1b-IX-V activation signalling |
| setSize | 10 |
| pANOVA | 0.00461 |
| s.dist | -0.517 |
| p.adjustANOVA | 0.0207 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| GP9 | -8129 |
| GP1BB | -7605 |
| VWF | -7509 |
| GP1BA | -6804 |
| PIK3R1 | -5262 |
| SRC | -3482 |
| FLNA | -3045 |
| GP5 | -2596 |
| RAF1 | -1300 |
| YWHAZ | 6237 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| GP9 | -8129 |
| GP1BB | -7605 |
| VWF | -7509 |
| GP1BA | -6804 |
| PIK3R1 | -5262 |
| SRC | -3482 |
| FLNA | -3045 |
| GP5 | -2596 |
| RAF1 | -1300 |
| YWHAZ | 6237 |
Glycogen storage diseases
| 462 | |
|---|---|
| set | Glycogen storage diseases |
| setSize | 13 |
| pANOVA | 0.00139 |
| s.dist | -0.512 |
| p.adjustANOVA | 0.00875 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| UBA52 | -8454 |
| UBB | -6926 |
| GYG1 | -6847 |
| GAA | -6769 |
| NHLRC1 | -5361 |
| G6PC3 | -4739 |
| UBC | -4156 |
| GYS1 | -3942 |
| GBE1 | -3577 |
| SLC37A4 | 566 |
| G6PC | 3272 |
| EPM2A | 5286 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| UBA52 | -8454 |
| UBB | -6926 |
| GYG1 | -6847 |
| GAA | -6769 |
| NHLRC1 | -5361 |
| G6PC3 | -4739 |
| UBC | -4156 |
| GYS1 | -3942 |
| GBE1 | -3577 |
| SLC37A4 | 566 |
| G6PC | 3272 |
| EPM2A | 5286 |
tRNA processing in the mitochondrion
| 1362 | |
|---|---|
| set | tRNA processing in the mitochondrion |
| setSize | 32 |
| pANOVA | 5.58e-07 |
| s.dist | -0.511 |
| p.adjustANOVA | 1.19e-05 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MT-TN | -9260 |
| MT-ATP8 | -9237 |
| MT-TS1 | -9205 |
| MT-TC | -8689 |
| MT-TA | -8331 |
| MT-ATP6 | -8247 |
| MT-TP | -8077 |
| MT-CO3 | -8066 |
| MT-ND3 | -7383 |
| MT-ND4L | -7200 |
| HSD17B10 | -7145 |
| MT-CO2 | -6670 |
| MT-ND1 | -5890 |
| MT-TV | -5625 |
| MT-TL2 | -5513 |
| MT-TY | -5400 |
| MT-ND2 | -5100 |
| ELAC2 | -5058 |
| MT-TM | -4720 |
| MT-TF | -4317 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MT-TN | -9260 |
| MT-ATP8 | -9237 |
| MT-TS1 | -9205 |
| MT-TC | -8689 |
| MT-TA | -8331 |
| MT-ATP6 | -8247 |
| MT-TP | -8077 |
| MT-CO3 | -8066 |
| MT-ND3 | -7383 |
| MT-ND4L | -7200 |
| HSD17B10 | -7145 |
| MT-CO2 | -6670 |
| MT-ND1 | -5890 |
| MT-TV | -5625 |
| MT-TL2 | -5513 |
| MT-TY | -5400 |
| MT-ND2 | -5100 |
| ELAC2 | -5058 |
| MT-TM | -4720 |
| MT-TF | -4317 |
| MT-CYB | -4300 |
| MT-ND5 | -3886 |
| MT-RNR1 | -2749 |
| MT-TL1 | -2174 |
| MT-CO1 | -1832 |
| MT-RNR2 | -1586 |
| MT-TE | -440 |
| MT-ND6 | 682 |
| PRORP | 5007 |
| MT-ND4 | 6120 |
| TRMT10C | 9005 |
| TRNT1 | 11283 |
Trafficking of GluR2-containing AMPA receptors
| 1249 | |
|---|---|
| set | Trafficking of GluR2-containing AMPA receptors |
| setSize | 12 |
| pANOVA | 0.00263 |
| s.dist | -0.501 |
| p.adjustANOVA | 0.0143 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| AP2M1 | -9075 |
| AP2S1 | -7871 |
| PICK1 | -7033 |
| AP2A2 | -6809 |
| AP2A1 | -6392 |
| NSF | -4759 |
| PRKCB | -4714 |
| PRKCA | -4463 |
| TSPAN7 | -2607 |
| AP2B1 | -1491 |
| GRIP1 | 602 |
| GRIA4 | 9323 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| AP2M1 | -9075 |
| AP2S1 | -7871 |
| PICK1 | -7033 |
| AP2A2 | -6809 |
| AP2A1 | -6392 |
| NSF | -4759 |
| PRKCB | -4714 |
| PRKCA | -4463 |
| TSPAN7 | -2607 |
| AP2B1 | -1491 |
| GRIP1 | 602 |
| GRIA4 | 9323 |
Regulation of expression of SLITs and ROBOs
| 982 | |
|---|---|
| set | Regulation of expression of SLITs and ROBOs |
| setSize | 162 |
| pANOVA | 5.02e-28 |
| s.dist | -0.499 |
| p.adjustANOVA | 3.81e-26 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| MAGOH | -9181 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| MAGOH | -9181 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| PSMB6 | -8981 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| PSMD2 | -8924 |
| RPS27A | -8920 |
| PSMB7 | -8904 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| ELOB | -8853 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| ROBO3 | -8735 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| PSMD3 | -8663 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| PSMD9 | -8602 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| PSMB5 | -8532 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| PSMD4 | -7754 |
| PSMC3 | -7739 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| EIF4A3 | -7329 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| PSMD13 | -7228 |
| SEM1 | -7202 |
| PSMD8 | -7189 |
| LDB1 | -7150 |
| PSMC5 | -6997 |
| PSMC4 | -6969 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| UBB | -6926 |
| EIF4G1 | -6857 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| PSMB10 | -6361 |
| PSMB4 | -6256 |
| ZSWIM8 | -6186 |
| PSMB1 | -5932 |
| RPL28 | -5853 |
| RPL26L1 | -5693 |
| PSMB3 | -5495 |
| PSMF1 | -5464 |
| PSMA7 | -5363 |
| RPL23A | -5130 |
| RBM8A | -4969 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| RPS3A | -4198 |
| UBC | -4156 |
| SLIT1 | -3712 |
| RNPS1 | -3636 |
| DAG1 | -3623 |
| RPL6 | -3572 |
| CASC3 | -2260 |
| PSMA2 | -1900 |
| PSMC1 | -1755 |
| UPF3A | -1277 |
| ELOC | -589 |
| RPS26 | -480 |
| PSMD6 | -394 |
| PSMB2 | 283 |
| PSMA1 | 433 |
| PSME3 | 483 |
| RPL22L1 | 543 |
| ROBO1 | 1551 |
| RPS4Y1 | 1781 |
| RBX1 | 1884 |
| GSPT2 | 2014 |
| PSMA8 | 2647 |
| PSMD7 | 2722 |
| PABPC1 | 2767 |
| PSMB9 | 2928 |
| MSI1 | 3005 |
| PSME1 | 3205 |
| RPSA | 3639 |
| PSMB8 | 3659 |
| PSMC2 | 4032 |
| ETF1 | 4209 |
| PSMD1 | 4367 |
| PSMA5 | 4469 |
| PSMD14 | 4877 |
| PSMD10 | 5090 |
| LHX4 | 5171 |
| UPF3B | 7058 |
| MAGOHB | 7470 |
| PSMD11 | 8028 |
| HOXA2 | 8470 |
| PSMA6 | 8998 |
| GSPT1 | 9073 |
| PSMC6 | 9298 |
| CUL2 | 9832 |
| RPS27L | 10040 |
| PSME2 | 10300 |
| PSME4 | 10448 |
| UPF2 | 10733 |
| RPL3L | 10975 |
| NCBP2 | 11197 |
| PSMA4 | 11467 |
| NCBP1 | 11649 |
| USP33 | 11673 |
| PSMD12 | 12185 |
| PSMD5 | 12195 |
| PSMA3 | 12678 |
Glycogen synthesis
| 463 | |
|---|---|
| set | Glycogen synthesis |
| setSize | 13 |
| pANOVA | 0.00201 |
| s.dist | -0.495 |
| p.adjustANOVA | 0.0118 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| UBA52 | -8454 |
| PGM1 | -7809 |
| UBB | -6926 |
| GYG1 | -6847 |
| NHLRC1 | -5361 |
| UBC | -4156 |
| PGM2 | -4124 |
| GYS1 | -3942 |
| GBE1 | -3577 |
| PGM2L1 | -706 |
| EPM2A | 5286 |
| UGP2 | 7456 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| UBA52 | -8454 |
| PGM1 | -7809 |
| UBB | -6926 |
| GYG1 | -6847 |
| NHLRC1 | -5361 |
| UBC | -4156 |
| PGM2 | -4124 |
| GYS1 | -3942 |
| GBE1 | -3577 |
| PGM2L1 | -706 |
| EPM2A | 5286 |
| UGP2 | 7456 |
RNA Polymerase I Promoter Opening
| 903 | |
|---|---|
| set | RNA Polymerase I Promoter Opening |
| setSize | 19 |
| pANOVA | 0.000215 |
| s.dist | -0.49 |
| p.adjustANOVA | 0.00191 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MAPK3 | -9270.0 |
| H2AZ1 | -8858.0 |
| H2AJ | -8549.0 |
| H2BC12 | -8076.0 |
| H2AZ2 | -6100.0 |
| UBTF | -6035.0 |
| H2BC5 | -5801.0 |
| H2BC9 | -5742.0 |
| H2BC11 | -5279.0 |
| H3C15 | -4715.5 |
| H2BC21 | -3775.0 |
| H2AC6 | -3542.0 |
| H2BC15 | -2448.0 |
| H2BC17 | -873.0 |
| H2BC4 | -582.0 |
| H3-3A | -48.0 |
| H2BU1 | 1259.0 |
| MBD2 | 3379.0 |
| H2AC20 | 5713.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MAPK3 | -9270.0 |
| H2AZ1 | -8858.0 |
| H2AJ | -8549.0 |
| H2BC12 | -8076.0 |
| H2AZ2 | -6100.0 |
| UBTF | -6035.0 |
| H2BC5 | -5801.0 |
| H2BC9 | -5742.0 |
| H2BC11 | -5279.0 |
| H3C15 | -4715.5 |
| H2BC21 | -3775.0 |
| H2AC6 | -3542.0 |
| H2BC15 | -2448.0 |
| H2BC17 | -873.0 |
| H2BC4 | -582.0 |
| H3-3A | -48.0 |
| H2BU1 | 1259.0 |
| MBD2 | 3379.0 |
| H2AC20 | 5713.0 |
Pausing and recovery of Tat-mediated HIV elongation
| 807 | |
|---|---|
| set | Pausing and recovery of Tat-mediated HIV elongation |
| setSize | 30 |
| pANOVA | 3.45e-06 |
| s.dist | -0.49 |
| p.adjustANOVA | 6.3e-05 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| POLR2L | -9269 |
| POLR2E | -9009 |
| NELFB | -8864 |
| ELOB | -8853 |
| CDK9 | -8696 |
| POLR2F | -8657 |
| POLR2G | -8638 |
| CTDP1 | -8450 |
| POLR2I | -8445 |
| POLR2J | -8226 |
| GTF2F1 | -7647 |
| POLR2H | -7192 |
| ELL | -6345 |
| SSRP1 | -5315 |
| SUPT5H | -5198 |
| NELFE | -5184 |
| POLR2C | -4979 |
| SUPT4H1 | -4193 |
| POLR2A | -1960 |
| NELFA | -1628 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| POLR2L | -9269 |
| POLR2E | -9009 |
| NELFB | -8864 |
| ELOB | -8853 |
| CDK9 | -8696 |
| POLR2F | -8657 |
| POLR2G | -8638 |
| CTDP1 | -8450 |
| POLR2I | -8445 |
| POLR2J | -8226 |
| GTF2F1 | -7647 |
| POLR2H | -7192 |
| ELL | -6345 |
| SSRP1 | -5315 |
| SUPT5H | -5198 |
| NELFE | -5184 |
| POLR2C | -4979 |
| SUPT4H1 | -4193 |
| POLR2A | -1960 |
| NELFA | -1628 |
| ELOC | -589 |
| NELFCD | -430 |
| GTF2F2 | 453 |
| POLR2B | 1553 |
| ELOA | 1830 |
| SUPT16H | 1885 |
| CCNT1 | 2384 |
| POLR2D | 5190 |
| TCEA1 | 7496 |
| POLR2K | 7850 |
Tat-mediated HIV elongation arrest and recovery
| 1218 | |
|---|---|
| set | Tat-mediated HIV elongation arrest and recovery |
| setSize | 30 |
| pANOVA | 3.45e-06 |
| s.dist | -0.49 |
| p.adjustANOVA | 6.3e-05 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| POLR2L | -9269 |
| POLR2E | -9009 |
| NELFB | -8864 |
| ELOB | -8853 |
| CDK9 | -8696 |
| POLR2F | -8657 |
| POLR2G | -8638 |
| CTDP1 | -8450 |
| POLR2I | -8445 |
| POLR2J | -8226 |
| GTF2F1 | -7647 |
| POLR2H | -7192 |
| ELL | -6345 |
| SSRP1 | -5315 |
| SUPT5H | -5198 |
| NELFE | -5184 |
| POLR2C | -4979 |
| SUPT4H1 | -4193 |
| POLR2A | -1960 |
| NELFA | -1628 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| POLR2L | -9269 |
| POLR2E | -9009 |
| NELFB | -8864 |
| ELOB | -8853 |
| CDK9 | -8696 |
| POLR2F | -8657 |
| POLR2G | -8638 |
| CTDP1 | -8450 |
| POLR2I | -8445 |
| POLR2J | -8226 |
| GTF2F1 | -7647 |
| POLR2H | -7192 |
| ELL | -6345 |
| SSRP1 | -5315 |
| SUPT5H | -5198 |
| NELFE | -5184 |
| POLR2C | -4979 |
| SUPT4H1 | -4193 |
| POLR2A | -1960 |
| NELFA | -1628 |
| ELOC | -589 |
| NELFCD | -430 |
| GTF2F2 | 453 |
| POLR2B | 1553 |
| ELOA | 1830 |
| SUPT16H | 1885 |
| CCNT1 | 2384 |
| POLR2D | 5190 |
| TCEA1 | 7496 |
| POLR2K | 7850 |
Hyaluronan uptake and degradation
| 506 | |
|---|---|
| set | Hyaluronan uptake and degradation |
| setSize | 10 |
| pANOVA | 0.00915 |
| s.dist | -0.476 |
| p.adjustANOVA | 0.0324 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| HYAL2 | -8261 |
| HEXA | -6991 |
| GUSB | -6463 |
| CD44 | -6207 |
| CHP1 | -6023 |
| SLC9A1 | -5968 |
| HYAL3 | -3530 |
| HEXB | -3456 |
| HMMR | 1987 |
| HYAL1 | 9992 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HYAL2 | -8261 |
| HEXA | -6991 |
| GUSB | -6463 |
| CD44 | -6207 |
| CHP1 | -6023 |
| SLC9A1 | -5968 |
| HYAL3 | -3530 |
| HEXB | -3456 |
| HMMR | 1987 |
| HYAL1 | 9992 |
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
| 717 | |
|---|---|
| set | Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters |
| setSize | 21 |
| pANOVA | 0.000167 |
| s.dist | -0.474 |
| p.adjustANOVA | 0.00162 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| AP2M1 | -9075 |
| AP1M1 | -8805 |
| HLA-A | -8778 |
| ARF1 | -8759 |
| AP2S1 | -7871 |
| AP1S1 | -7669 |
| AP1B1 | -7624 |
| AP1M2 | -6904 |
| AP2A2 | -6809 |
| CD4 | -6490 |
| AP2A1 | -6392 |
| CD28 | -4635 |
| PACS1 | -4238 |
| LCK | -3519 |
| ATP6V1H | -2560 |
| AP2B1 | -1491 |
| AP1G1 | 3675 |
| CD8B | 4871 |
| AP1S3 | 5959 |
| AP1S2 | 6936 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| AP2M1 | -9075 |
| AP1M1 | -8805 |
| HLA-A | -8778 |
| ARF1 | -8759 |
| AP2S1 | -7871 |
| AP1S1 | -7669 |
| AP1B1 | -7624 |
| AP1M2 | -6904 |
| AP2A2 | -6809 |
| CD4 | -6490 |
| AP2A1 | -6392 |
| CD28 | -4635 |
| PACS1 | -4238 |
| LCK | -3519 |
| ATP6V1H | -2560 |
| AP2B1 | -1491 |
| AP1G1 | 3675 |
| CD8B | 4871 |
| AP1S3 | 5959 |
| AP1S2 | 6936 |
| B2M | 7258 |
Diseases of carbohydrate metabolism
| 293 | |
|---|---|
| set | Diseases of carbohydrate metabolism |
| setSize | 29 |
| pANOVA | 9.84e-06 |
| s.dist | -0.474 |
| p.adjustANOVA | 0.000154 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| SGSH | -8871 |
| UBA52 | -8454 |
| NAGLU | -7870 |
| RPIA | -7209 |
| UBB | -6926 |
| GYG1 | -6847 |
| GAA | -6769 |
| GUSB | -6463 |
| IDUA | -5903 |
| KHK | -5807 |
| NHLRC1 | -5361 |
| TALDO1 | -5350 |
| G6PC3 | -4739 |
| GLB1 | -4294 |
| UBC | -4156 |
| GYS1 | -3942 |
| GALNS | -3866 |
| DCXR | -3631 |
| GBE1 | -3577 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| SGSH | -8871 |
| UBA52 | -8454 |
| NAGLU | -7870 |
| RPIA | -7209 |
| UBB | -6926 |
| GYG1 | -6847 |
| GAA | -6769 |
| GUSB | -6463 |
| IDUA | -5903 |
| KHK | -5807 |
| NHLRC1 | -5361 |
| TALDO1 | -5350 |
| G6PC3 | -4739 |
| GLB1 | -4294 |
| UBC | -4156 |
| GYS1 | -3942 |
| GALNS | -3866 |
| DCXR | -3631 |
| GBE1 | -3577 |
| IDS | -2509 |
| GNS | -1497 |
| HGSNAT | -756 |
| SLC37A4 | 566 |
| ARSB | 1964 |
| ALDOB | 2063 |
| G6PC | 3272 |
| EPM2A | 5286 |
| HYAL1 | 9992 |
Assembly Of The HIV Virion
| 87 | |
|---|---|
| set | Assembly Of The HIV Virion |
| setSize | 15 |
| pANOVA | 0.00148 |
| s.dist | -0.474 |
| p.adjustANOVA | 0.0092 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| FURIN | -9250 |
| RPS27A | -8920 |
| VPS28 | -8764 |
| MVB12A | -8489 |
| UBA52 | -8454 |
| VPS37B | -7260 |
| UBB | -6926 |
| PPIA | -6435 |
| UBAP1 | -5567 |
| UBC | -4156 |
| VPS37C | -971 |
| MVB12B | -724 |
| TSG101 | 4524 |
| NMT2 | 9221 |
| VPS37A | 10118 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| FURIN | -9250 |
| RPS27A | -8920 |
| VPS28 | -8764 |
| MVB12A | -8489 |
| UBA52 | -8454 |
| VPS37B | -7260 |
| UBB | -6926 |
| PPIA | -6435 |
| UBAP1 | -5567 |
| UBC | -4156 |
| VPS37C | -971 |
| MVB12B | -724 |
| TSG101 | 4524 |
| NMT2 | 9221 |
| VPS37A | 10118 |
Advanced glycosylation endproduct receptor signaling
| 61 | |
|---|---|
| set | Advanced glycosylation endproduct receptor signaling |
| setSize | 12 |
| pANOVA | 0.00447 |
| s.dist | -0.474 |
| p.adjustANOVA | 0.0203 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MAPK3 | -9270 |
| DDOST | -9015 |
| PRKCSH | -8979 |
| S100A12 | -8231 |
| APP | -6325 |
| S100B | -6311 |
| LGALS3 | -5162 |
| MAPK1 | -1557 |
| AGER | -813 |
| HMGB1 | 2437 |
| CAPZA2 | 5051 |
| CAPZA1 | 6538 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MAPK3 | -9270 |
| DDOST | -9015 |
| PRKCSH | -8979 |
| S100A12 | -8231 |
| APP | -6325 |
| S100B | -6311 |
| LGALS3 | -5162 |
| MAPK1 | -1557 |
| AGER | -813 |
| HMGB1 | 2437 |
| CAPZA2 | 5051 |
| CAPZA1 | 6538 |
EGFR downregulation
| 320 | |
|---|---|
| set | EGFR downregulation |
| setSize | 27 |
| pANOVA | 3.15e-05 |
| s.dist | -0.463 |
| p.adjustANOVA | 0.000398 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| UBA52 | -8454 |
| HBEGF | -8399 |
| SH3GL1 | -8292 |
| EPN1 | -8220 |
| AREG | -7998 |
| SPRY1 | -7655 |
| PTPRK | -7532 |
| EREG | -7447 |
| UBB | -6926 |
| ARHGEF7 | -6629 |
| EGF | -5815 |
| GRB2 | -5369 |
| TGFA | -5356 |
| EPS15L1 | -5220 |
| PTPN12 | -4229 |
| UBC | -4156 |
| SPRY2 | -3912 |
| PTPN3 | -1749 |
| CBL | -1682 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| UBA52 | -8454 |
| HBEGF | -8399 |
| SH3GL1 | -8292 |
| EPN1 | -8220 |
| AREG | -7998 |
| SPRY1 | -7655 |
| PTPRK | -7532 |
| EREG | -7447 |
| UBB | -6926 |
| ARHGEF7 | -6629 |
| EGF | -5815 |
| GRB2 | -5369 |
| TGFA | -5356 |
| EPS15L1 | -5220 |
| PTPN12 | -4229 |
| UBC | -4156 |
| SPRY2 | -3912 |
| PTPN3 | -1749 |
| CBL | -1682 |
| SH3KBP1 | -783 |
| HGS | -528 |
| EPGN | 1789 |
| STAM | 3971 |
| CDC42 | 5814 |
| STAM2 | 11704 |
| EPS15 | 11769 |
Retrograde neurotrophin signalling
| 1013 | |
|---|---|
| set | Retrograde neurotrophin signalling |
| setSize | 12 |
| pANOVA | 0.0057 |
| s.dist | -0.461 |
| p.adjustANOVA | 0.0239 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| AP2M1 | -9075 |
| DNAL4 | -8486 |
| DNM2 | -8240 |
| AP2S1 | -7871 |
| AP2A2 | -6809 |
| AP2A1 | -6392 |
| CLTA | -6017 |
| CLTC | -1627 |
| AP2B1 | -1491 |
| DNM3 | -1122 |
| NTRK1 | 7637 |
| DNM1 | 9595 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| AP2M1 | -9075 |
| DNAL4 | -8486 |
| DNM2 | -8240 |
| AP2S1 | -7871 |
| AP2A2 | -6809 |
| AP2A1 | -6392 |
| CLTA | -6017 |
| CLTC | -1627 |
| AP2B1 | -1491 |
| DNM3 | -1122 |
| NTRK1 | 7637 |
| DNM1 | 9595 |
Heparan sulfate/heparin (HS-GAG) metabolism
| 498 | |
|---|---|
| set | Heparan sulfate/heparin (HS-GAG) metabolism |
| setSize | 38 |
| pANOVA | 9.09e-07 |
| s.dist | -0.46 |
| p.adjustANOVA | 1.88e-05 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SGSH | -8871 |
| GPC4 | -8599 |
| XYLT1 | -8163 |
| NAGLU | -7870 |
| B3GAT3 | -7628 |
| B3GALT6 | -7527 |
| HS3ST3A1 | -7186 |
| NDST1 | -6736 |
| SDC4 | -6556 |
| GUSB | -6463 |
| HS6ST1 | -6182 |
| IDUA | -5903 |
| VCAN | -5852 |
| XYLT2 | -5595 |
| NDST2 | -5390 |
| GPC2 | -4351 |
| GLB1 | -4294 |
| GLCE | -4252 |
| HS3ST3B1 | -3913 |
| DCN | -3528 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SGSH | -8871 |
| GPC4 | -8599 |
| XYLT1 | -8163 |
| NAGLU | -7870 |
| B3GAT3 | -7628 |
| B3GALT6 | -7527 |
| HS3ST3A1 | -7186 |
| NDST1 | -6736 |
| SDC4 | -6556 |
| GUSB | -6463 |
| HS6ST1 | -6182 |
| IDUA | -5903 |
| VCAN | -5852 |
| XYLT2 | -5595 |
| NDST2 | -5390 |
| GPC2 | -4351 |
| GLB1 | -4294 |
| GLCE | -4252 |
| HS3ST3B1 | -3913 |
| DCN | -3528 |
| HS2ST1 | -3321 |
| GPC1 | -3166 |
| EXT2 | -3099 |
| B4GALT7 | -2929 |
| IDS | -2509 |
| EXT1 | -1185 |
| B3GAT2 | -960 |
| GLB1L | -426 |
| HPSE | -223 |
| HSPG2 | 202 |
| SDC2 | 317 |
| SDC3 | 325 |
| HS3ST1 | 523 |
| CSPG4 | 627 |
| SLC35D2 | 1026 |
| HS3ST2 | 1470 |
| B3GAT1 | 2158 |
| AGRN | 10192 |
Influenza Infection
| 528 | |
|---|---|
| set | Influenza Infection |
| setSize | 154 |
| pANOVA | 8.95e-23 |
| s.dist | -0.458 |
| p.adjustANOVA | 3.82e-21 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SLC25A6 | -9291 |
| RPS2 | -9277 |
| RPL37 | -9273 |
| POLR2L | -9269 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SLC25A6 | -9291 |
| RPS2 | -9277 |
| RPL37 | -9273 |
| POLR2L | -9269 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| POLR2E | -9009 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| POLR2F | -8657 |
| RPL18 | -8654 |
| POLR2G | -8638 |
| RPL39 | -8609 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| POLR2I | -8445 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| POLR2J | -8226 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| TGFB1 | -7823 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| GTF2F1 | -7647 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| HSPA1A | -7231 |
| POLR2H | -7192 |
| PABPN1 | -7130 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| POM121C | -6837 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| CPSF4 | -6511 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| CLTA | -6017 |
| SEC13 | -5867 |
| RPL28 | -5853 |
| RPL26L1 | -5693 |
| RPL23A | -5130 |
| POLR2C | -4979 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| NUP62 | -4381 |
| RPS3A | -4198 |
| NUP210 | -4025 |
| RPL6 | -3572 |
| POM121 | -3172 |
| NUP188 | -3159 |
| AAAS | -2187 |
| POLR2A | -1960 |
| IPO5 | -1656 |
| CLTC | -1627 |
| PARP1 | -1595 |
| RPS26 | -480 |
| NUP214 | -395 |
| CANX | 275 |
| RAN | 295 |
| GTF2F2 | 453 |
| RPL22L1 | 543 |
| NUP37 | 1467 |
| POLR2B | 1553 |
| GRSF1 | 1588 |
| RPS4Y1 | 1781 |
| NUP205 | 2600 |
| NUP98 | 2880 |
| NUP85 | 3065 |
| NDC1 | 3196 |
| CALR | 3246 |
| NUP35 | 3316 |
| RPSA | 3639 |
| NUP133 | 4455 |
| RAE1 | 4630 |
| DNAJC3 | 4700 |
| NUP153 | 4974 |
| POLR2D | 5190 |
| KPNA2 | 5284 |
| NUP88 | 5983 |
| NUP58 | 6170 |
| KPNA1 | 6413 |
| NUP93 | 6656 |
| HSP90AA1 | 7453 |
| NUP160 | 7636 |
| NUP155 | 7756 |
| NUP50 | 7773 |
| POLR2K | 7850 |
| RANBP2 | 8025 |
| SEH1L | 8036 |
| KPNA3 | 8923 |
| TPR | 9075 |
| KPNA4 | 9812 |
| KPNB1 | 9837 |
| RPS27L | 10040 |
| NUP107 | 10450 |
| RPL3L | 10975 |
| NUP42 | 11590 |
| KPNA5 | 11756 |
| NUP43 | 11811 |
| XPO1 | 12093 |
| ISG15 | 12334 |
| NUP54 | 12575 |
| EIF2AK2 | 12804 |
SUMOylation of immune response proteins
| 1051 | |
|---|---|
| set | SUMOylation of immune response proteins |
| setSize | 11 |
| pANOVA | 0.00922 |
| s.dist | -0.453 |
| p.adjustANOVA | 0.0325 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| NFKBIA | -8313 |
| RELA | -7350 |
| PIAS4 | -6402 |
| IKBKG | -5789 |
| IKBKE | -5700 |
| UBE2I | -4249 |
| NFKB2 | -3212 |
| SUMO3 | -1535 |
| PIAS3 | 594 |
| TOPORS | 844 |
| SUMO1 | 5448 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| NFKBIA | -8313 |
| RELA | -7350 |
| PIAS4 | -6402 |
| IKBKG | -5789 |
| IKBKE | -5700 |
| UBE2I | -4249 |
| NFKB2 | -3212 |
| SUMO3 | -1535 |
| PIAS3 | 594 |
| TOPORS | 844 |
| SUMO1 | 5448 |
Cytosolic iron-sulfur cluster assembly
| 229 | |
|---|---|
| set | Cytosolic iron-sulfur cluster assembly |
| setSize | 13 |
| pANOVA | 0.005 |
| s.dist | -0.45 |
| p.adjustANOVA | 0.0218 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CIAO2B | -8150 |
| NUBP2 | -8144 |
| CIAPIN1 | -6440 |
| POLD1 | -6423 |
| CIAO3 | -6326 |
| NUBP1 | -5679 |
| ERCC2 | -3632 |
| CIAO1 | -3595 |
| MMS19 | -3035 |
| RTEL1 | -1912 |
| ABCB7 | -1556 |
| NDOR1 | 4111 |
| BRIP1 | 9186 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CIAO2B | -8150 |
| NUBP2 | -8144 |
| CIAPIN1 | -6440 |
| POLD1 | -6423 |
| CIAO3 | -6326 |
| NUBP1 | -5679 |
| ERCC2 | -3632 |
| CIAO1 | -3595 |
| MMS19 | -3035 |
| RTEL1 | -1912 |
| ABCB7 | -1556 |
| NDOR1 | 4111 |
| BRIP1 | 9186 |
Spry regulation of FGF signaling
| 1153 | |
|---|---|
| set | Spry regulation of FGF signaling |
| setSize | 16 |
| pANOVA | 0.00188 |
| s.dist | -0.449 |
| p.adjustANOVA | 0.011 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MAPK3 | -9270 |
| RPS27A | -8920 |
| UBA52 | -8454 |
| PPP2R1A | -8177 |
| UBB | -6926 |
| GRB2 | -5369 |
| UBC | -4156 |
| SPRY2 | -3912 |
| SRC | -3482 |
| MKNK1 | -1865 |
| CBL | -1682 |
| MAPK1 | -1557 |
| PPP2CA | -317 |
| PTPN11 | 977 |
| PPP2CB | 4891 |
| BRAF | 7148 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MAPK3 | -9270 |
| RPS27A | -8920 |
| UBA52 | -8454 |
| PPP2R1A | -8177 |
| UBB | -6926 |
| GRB2 | -5369 |
| UBC | -4156 |
| SPRY2 | -3912 |
| SRC | -3482 |
| MKNK1 | -1865 |
| CBL | -1682 |
| MAPK1 | -1557 |
| PPP2CA | -317 |
| PTPN11 | 977 |
| PPP2CB | 4891 |
| BRAF | 7148 |
Cristae formation
| 220 | |
|---|---|
| set | Cristae formation |
| setSize | 31 |
| pANOVA | 1.52e-05 |
| s.dist | -0.449 |
| p.adjustANOVA | 0.000219 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MT-ATP8 | -9237 |
| ATP5ME | -9114 |
| ATP5MG | -9055 |
| ATP5F1D | -8993 |
| ATP5MF | -8988 |
| ATP5MC2 | -8655 |
| MICOS13 | -8463 |
| MT-ATP6 | -8247 |
| MTX1 | -7782 |
| SAMM50 | -7478 |
| ATP5F1E | -7305 |
| ATP5F1A | -7191 |
| ATP5MC3 | -6943 |
| CHCHD6 | -6472 |
| ATP5PB | -5586 |
| ATP5F1B | -4642 |
| ATP5PF | -4410 |
| TMEM11 | -4137 |
| CHCHD3 | -3400 |
| ATP5PO | -2733 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MT-ATP8 | -9237 |
| ATP5ME | -9114 |
| ATP5MG | -9055 |
| ATP5F1D | -8993 |
| ATP5MF | -8988 |
| ATP5MC2 | -8655 |
| MICOS13 | -8463 |
| MT-ATP6 | -8247 |
| MTX1 | -7782 |
| SAMM50 | -7478 |
| ATP5F1E | -7305 |
| ATP5F1A | -7191 |
| ATP5MC3 | -6943 |
| CHCHD6 | -6472 |
| ATP5PB | -5586 |
| ATP5F1B | -4642 |
| ATP5PF | -4410 |
| TMEM11 | -4137 |
| CHCHD3 | -3400 |
| ATP5PO | -2733 |
| MICOS10 | -2244 |
| DNAJC11 | -1741 |
| HSPA9 | -1401 |
| ATP5MC1 | -1306 |
| ATP5PD | -1292 |
| ATP5F1C | 2542 |
| APOO | 6872 |
| IMMT | 8285 |
| MTX2 | 8643 |
| APOOL | 10089 |
| DMAC2L | 11593 |
The role of Nef in HIV-1 replication and disease pathogenesis
| 1232 | |
|---|---|
| set | The role of Nef in HIV-1 replication and disease pathogenesis |
| setSize | 28 |
| pANOVA | 4.32e-05 |
| s.dist | -0.446 |
| p.adjustANOVA | 0.000521 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| AP2M1 | -9075 |
| AP1M1 | -8805 |
| HLA-A | -8778 |
| ARF1 | -8759 |
| AP2S1 | -7871 |
| AP1S1 | -7669 |
| AP1B1 | -7624 |
| AP1M2 | -6904 |
| AP2A2 | -6809 |
| CD247 | -6585 |
| CD4 | -6490 |
| AP2A1 | -6392 |
| ELMO1 | -6208 |
| CD28 | -4635 |
| FYN | -4397 |
| PACS1 | -4238 |
| DOCK2 | -4131 |
| LCK | -3519 |
| HCK | -2682 |
| ATP6V1H | -2560 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| AP2M1 | -9075 |
| AP1M1 | -8805 |
| HLA-A | -8778 |
| ARF1 | -8759 |
| AP2S1 | -7871 |
| AP1S1 | -7669 |
| AP1B1 | -7624 |
| AP1M2 | -6904 |
| AP2A2 | -6809 |
| CD247 | -6585 |
| CD4 | -6490 |
| AP2A1 | -6392 |
| ELMO1 | -6208 |
| CD28 | -4635 |
| FYN | -4397 |
| PACS1 | -4238 |
| DOCK2 | -4131 |
| LCK | -3519 |
| HCK | -2682 |
| ATP6V1H | -2560 |
| AP2B1 | -1491 |
| RAC1 | 3573 |
| AP1G1 | 3675 |
| PAK2 | 4813 |
| CD8B | 4871 |
| AP1S3 | 5959 |
| AP1S2 | 6936 |
| B2M | 7258 |
Signal regulatory protein family interactions
| 1072 | |
|---|---|
| set | Signal regulatory protein family interactions |
| setSize | 12 |
| pANOVA | 0.0081 |
| s.dist | -0.441 |
| p.adjustANOVA | 0.03 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SIRPB1 | -8055 |
| SIRPA | -8013 |
| PTK2B | -7693 |
| TYROBP | -7100 |
| SIRPG | -6225 |
| GRB2 | -5369 |
| SRC | -3482 |
| PTPN6 | -830 |
| PTK2 | -643 |
| SKAP2 | -504 |
| PTPN11 | 977 |
| CD47 | 9616 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SIRPB1 | -8055 |
| SIRPA | -8013 |
| PTK2B | -7693 |
| TYROBP | -7100 |
| SIRPG | -6225 |
| GRB2 | -5369 |
| SRC | -3482 |
| PTPN6 | -830 |
| PTK2 | -643 |
| SKAP2 | -504 |
| PTPN11 | 977 |
| CD47 | 9616 |
PKA activation in glucagon signalling
| 795 | |
|---|---|
| set | PKA activation in glucagon signalling |
| setSize | 14 |
| pANOVA | 0.00468 |
| s.dist | -0.436 |
| p.adjustANOVA | 0.0208 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| ADCY9 | -8692 |
| PRKAR2B | -7977 |
| ADCY3 | -6347 |
| PRKACA | -6194 |
| PRKAR1B | -5101 |
| ADCY5 | -4691 |
| GNAS | -4625 |
| ADCY6 | -4556 |
| ADCY7 | -4056 |
| PRKAR2A | -370 |
| PRKAR1A | 1283 |
| ADCY4 | 1838 |
| PRKACB | 3080 |
| ADCY2 | 3640 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ADCY9 | -8692 |
| PRKAR2B | -7977 |
| ADCY3 | -6347 |
| PRKACA | -6194 |
| PRKAR1B | -5101 |
| ADCY5 | -4691 |
| GNAS | -4625 |
| ADCY6 | -4556 |
| ADCY7 | -4056 |
| PRKAR2A | -370 |
| PRKAR1A | 1283 |
| ADCY4 | 1838 |
| PRKACB | 3080 |
| ADCY2 | 3640 |
DNA methylation
| 247 | |
|---|---|
| set | DNA methylation |
| setSize | 20 |
| pANOVA | 0.000727 |
| s.dist | -0.436 |
| p.adjustANOVA | 0.0053 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| H2AZ1 | -8858.0 |
| H2AJ | -8549.0 |
| H2BC12 | -8076.0 |
| H2AZ2 | -6100.0 |
| H2BC5 | -5801.0 |
| H2BC9 | -5742.0 |
| H2BC11 | -5279.0 |
| H3C15 | -4715.5 |
| DNMT1 | -4185.0 |
| DNMT3A | -4089.0 |
| H2BC21 | -3775.0 |
| H2AC6 | -3542.0 |
| H2BC15 | -2448.0 |
| DNMT3B | -2032.0 |
| H2BC17 | -873.0 |
| H2BC4 | -582.0 |
| H3-3A | -48.0 |
| H2BU1 | 1259.0 |
| H2AC20 | 5713.0 |
| UHRF1 | 6663.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H2AZ1 | -8858.0 |
| H2AJ | -8549.0 |
| H2BC12 | -8076.0 |
| H2AZ2 | -6100.0 |
| H2BC5 | -5801.0 |
| H2BC9 | -5742.0 |
| H2BC11 | -5279.0 |
| H3C15 | -4715.5 |
| DNMT1 | -4185.0 |
| DNMT3A | -4089.0 |
| H2BC21 | -3775.0 |
| H2AC6 | -3542.0 |
| H2BC15 | -2448.0 |
| DNMT3B | -2032.0 |
| H2BC17 | -873.0 |
| H2BC4 | -582.0 |
| H3-3A | -48.0 |
| H2BU1 | 1259.0 |
| H2AC20 | 5713.0 |
| UHRF1 | 6663.0 |
Abortive elongation of HIV-1 transcript in the absence of Tat
| 29 | |
|---|---|
| set | Abortive elongation of HIV-1 transcript in the absence of Tat |
| setSize | 23 |
| pANOVA | 0.000295 |
| s.dist | -0.436 |
| p.adjustANOVA | 0.0025 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| POLR2L | -9269 |
| POLR2E | -9009 |
| NELFB | -8864 |
| POLR2F | -8657 |
| POLR2G | -8638 |
| CTDP1 | -8450 |
| POLR2I | -8445 |
| POLR2J | -8226 |
| GTF2F1 | -7647 |
| POLR2H | -7192 |
| SUPT5H | -5198 |
| NELFE | -5184 |
| POLR2C | -4979 |
| SUPT4H1 | -4193 |
| POLR2A | -1960 |
| NELFA | -1628 |
| NELFCD | -430 |
| GTF2F2 | 453 |
| POLR2B | 1553 |
| POLR2D | 5190 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| POLR2L | -9269 |
| POLR2E | -9009 |
| NELFB | -8864 |
| POLR2F | -8657 |
| POLR2G | -8638 |
| CTDP1 | -8450 |
| POLR2I | -8445 |
| POLR2J | -8226 |
| GTF2F1 | -7647 |
| POLR2H | -7192 |
| SUPT5H | -5198 |
| NELFE | -5184 |
| POLR2C | -4979 |
| SUPT4H1 | -4193 |
| POLR2A | -1960 |
| NELFA | -1628 |
| NELFCD | -430 |
| GTF2F2 | 453 |
| POLR2B | 1553 |
| POLR2D | 5190 |
| POLR2K | 7850 |
| NCBP2 | 11197 |
| NCBP1 | 11649 |
Hyaluronan metabolism
| 505 | |
|---|---|
| set | Hyaluronan metabolism |
| setSize | 13 |
| pANOVA | 0.00666 |
| s.dist | -0.435 |
| p.adjustANOVA | 0.0264 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| HYAL2 | -8261 |
| HEXA | -6991 |
| GUSB | -6463 |
| ABCC5 | -6327 |
| CD44 | -6207 |
| CHP1 | -6023 |
| SLC9A1 | -5968 |
| HYAL3 | -3530 |
| HEXB | -3456 |
| HAS3 | -782 |
| HMMR | 1987 |
| CEMIP | 2586 |
| HYAL1 | 9992 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HYAL2 | -8261 |
| HEXA | -6991 |
| GUSB | -6463 |
| ABCC5 | -6327 |
| CD44 | -6207 |
| CHP1 | -6023 |
| SLC9A1 | -5968 |
| HYAL3 | -3530 |
| HEXB | -3456 |
| HAS3 | -782 |
| HMMR | 1987 |
| CEMIP | 2586 |
| HYAL1 | 9992 |
NOTCH3 Activation and Transmission of Signal to the Nucleus
| 706 | |
|---|---|
| set | NOTCH3 Activation and Transmission of Signal to the Nucleus |
| setSize | 23 |
| pANOVA | 0.000315 |
| s.dist | -0.434 |
| p.adjustANOVA | 0.00266 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| NEURL1B | -9191 |
| RPS27A | -8920 |
| APH1A | -8782 |
| UBA52 | -8454 |
| TACC3 | -7803 |
| JAG1 | -6938 |
| UBB | -6926 |
| YBX1 | -6452 |
| EGF | -5815 |
| NOTCH3 | -5487 |
| UBC | -4156 |
| MIB2 | -3856 |
| PSENEN | -3548 |
| WWP2 | -3090 |
| NCSTN | -1450 |
| DLL1 | -759 |
| PSEN2 | -100 |
| MIB1 | 335 |
| ADAM10 | 1007 |
| JAG2 | 2060 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| NEURL1B | -9191 |
| RPS27A | -8920 |
| APH1A | -8782 |
| UBA52 | -8454 |
| TACC3 | -7803 |
| JAG1 | -6938 |
| UBB | -6926 |
| YBX1 | -6452 |
| EGF | -5815 |
| NOTCH3 | -5487 |
| UBC | -4156 |
| MIB2 | -3856 |
| PSENEN | -3548 |
| WWP2 | -3090 |
| NCSTN | -1450 |
| DLL1 | -759 |
| PSEN2 | -100 |
| MIB1 | 335 |
| ADAM10 | 1007 |
| JAG2 | 2060 |
| PSEN1 | 3518 |
| NEURL1 | 7439 |
| APH1B | 7814 |
ERBB2 Regulates Cell Motility
| 330 | |
|---|---|
| set | ERBB2 Regulates Cell Motility |
| setSize | 10 |
| pANOVA | 0.0175 |
| s.dist | -0.434 |
| p.adjustANOVA | 0.0538 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| HBEGF | -8399 |
| EREG | -7447 |
| NRG1 | -6772 |
| EGF | -5815 |
| ERBB2 | -3699 |
| DIAPH1 | -2283 |
| NRG4 | -1472 |
| MEMO1 | -1233 |
| RHOA | -387 |
| ERBB3 | 7242 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HBEGF | -8399 |
| EREG | -7447 |
| NRG1 | -6772 |
| EGF | -5815 |
| ERBB2 | -3699 |
| DIAPH1 | -2283 |
| NRG4 | -1472 |
| MEMO1 | -1233 |
| RHOA | -387 |
| ERBB3 | 7242 |
HS-GAG degradation
| 488 | |
|---|---|
| set | HS-GAG degradation |
| setSize | 16 |
| pANOVA | 0.00273 |
| s.dist | -0.433 |
| p.adjustANOVA | 0.0147 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SGSH | -8871 |
| GPC4 | -8599 |
| NAGLU | -7870 |
| SDC4 | -6556 |
| GUSB | -6463 |
| IDUA | -5903 |
| GPC2 | -4351 |
| GLB1 | -4294 |
| GPC1 | -3166 |
| IDS | -2509 |
| GLB1L | -426 |
| HPSE | -223 |
| HSPG2 | 202 |
| SDC2 | 317 |
| SDC3 | 325 |
| AGRN | 10192 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SGSH | -8871 |
| GPC4 | -8599 |
| NAGLU | -7870 |
| SDC4 | -6556 |
| GUSB | -6463 |
| IDUA | -5903 |
| GPC2 | -4351 |
| GLB1 | -4294 |
| GPC1 | -3166 |
| IDS | -2509 |
| GLB1L | -426 |
| HPSE | -223 |
| HSPG2 | 202 |
| SDC2 | 317 |
| SDC3 | 325 |
| AGRN | 10192 |
Olfactory Signaling Pathway
| 767 | |
|---|---|
| set | Olfactory Signaling Pathway |
| setSize | 61 |
| pANOVA | 5.25e-09 |
| s.dist | 0.432 |
| p.adjustANOVA | 1.41e-07 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| OR2AT4 | 12782 |
| OR2G6 | 12722 |
| OR2M3 | 12694 |
| OR6Y1 | 12484 |
| RTP4 | 12403 |
| OR8A1 | 12265 |
| OR10A6 | 12143 |
| OR7C1 | 12095 |
| OR6C75 | 12067 |
| OR52N4 | 12064 |
| OR2C3 | 11959 |
| OR7A5 | 11681 |
| OR5A2 | 11663 |
| OR10H5 | 11595 |
| OR2I1P | 11562 |
| OR2A5 | 11389 |
| OR1D2 | 11324 |
| OR5AS1 | 11224 |
| OR1C1 | 11206 |
| OR10G3 | 11172 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| OR2AT4 | 12782 |
| OR2G6 | 12722 |
| OR2M3 | 12694 |
| OR6Y1 | 12484 |
| RTP4 | 12403 |
| OR8A1 | 12265 |
| OR10A6 | 12143 |
| OR7C1 | 12095 |
| OR6C75 | 12067 |
| OR52N4 | 12064 |
| OR2C3 | 11959 |
| OR7A5 | 11681 |
| OR5A2 | 11663 |
| OR10H5 | 11595 |
| OR2I1P | 11562 |
| OR2A5 | 11389 |
| OR1D2 | 11324 |
| OR5AS1 | 11224 |
| OR1C1 | 11206 |
| OR10G3 | 11172 |
| OR1I1 | 11073 |
| OR2V2 | 10962 |
| OR2T33 | 10726 |
| OR6K3 | 10494 |
| OR5A1 | 10419 |
| OR2M4 | 10031 |
| OR14L1P | 9428 |
| OR52K1 | 9149 |
| OR56A1 | 9083 |
| OR14J1 | 8823 |
| OR4K17 | 8753 |
| REEP1 | 8488 |
| OR4E1 | 8461 |
| OR7D4 | 8448 |
| OR2L2 | 8231 |
| OR7G2 | 7620 |
| REEP3 | 7597 |
| OR2H2 | 7543 |
| OR51L1 | 6405 |
| OR4D9 | 6399 |
| OR5AU1 | 4373 |
| OR5AN1 | 4342 |
| OR7A17 | 4323 |
| OR2W3 | 3973 |
| OR7D2 | 3617 |
| OR1M1 | 2261 |
| OR1A1 | 2092 |
| REEP2 | 1217 |
| OR4D1 | 534 |
| OR2A7 | -936 |
| OR52A1 | -1004 |
| OR2B11 | -1251 |
| OR2A1 | -1426 |
| RTP5 | -1548 |
| GNAL | -2812 |
| OR10AC1 | -2953 |
| REEP5 | -4223 |
| OR3A3 | -5531 |
| GNB1 | -6016 |
| REEP4 | -8314 |
| REEP6 | -8586 |
Complex I biogenesis
| 204 | |
|---|---|
| set | Complex I biogenesis |
| setSize | 55 |
| pANOVA | 3.44e-08 |
| s.dist | -0.43 |
| p.adjustANOVA | 7.84e-07 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| NDUFA13 | -9149 |
| NDUFA2 | -9096 |
| NDUFB2 | -8996 |
| NDUFA1 | -8947 |
| NDUFS6 | -8919 |
| NDUFB10 | -8842 |
| NDUFB1 | -8779 |
| NDUFB9 | -8627 |
| NDUFB8 | -8467 |
| NDUFS8 | -8382 |
| NDUFB7 | -8324 |
| NDUFC2 | -8123 |
| NDUFAF3 | -8118 |
| NDUFS5 | -8090 |
| NDUFA7 | -7443 |
| MT-ND3 | -7383 |
| NDUFA3 | -7374 |
| NDUFS3 | -7081 |
| NDUFS7 | -7074 |
| NDUFB11 | -6957 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| NDUFA13 | -9149 |
| NDUFA2 | -9096 |
| NDUFB2 | -8996 |
| NDUFA1 | -8947 |
| NDUFS6 | -8919 |
| NDUFB10 | -8842 |
| NDUFB1 | -8779 |
| NDUFB9 | -8627 |
| NDUFB8 | -8467 |
| NDUFS8 | -8382 |
| NDUFB7 | -8324 |
| NDUFC2 | -8123 |
| NDUFAF3 | -8118 |
| NDUFS5 | -8090 |
| NDUFA7 | -7443 |
| MT-ND3 | -7383 |
| NDUFA3 | -7374 |
| NDUFS3 | -7081 |
| NDUFS7 | -7074 |
| NDUFB11 | -6957 |
| ECSIT | -6932 |
| NDUFV1 | -6747 |
| NDUFA11 | -6299 |
| MT-ND1 | -5890 |
| ACAD9 | -5767 |
| NDUFAB1 | -5641 |
| NDUFB4 | -5418 |
| MT-ND2 | -5100 |
| NDUFA6 | -4947 |
| NDUFB3 | -4315 |
| NDUFS2 | -4259 |
| NDUFC1 | -4127 |
| MT-ND5 | -3886 |
| NDUFV3 | -2226 |
| NDUFA12 | -1259 |
| NDUFB6 | -1111 |
| NDUFA10 | -980 |
| NDUFAF5 | -905 |
| NDUFA8 | -468 |
| NDUFS4 | 273 |
| NDUFS1 | 530 |
| NDUFAF2 | 540 |
| MT-ND6 | 682 |
| NDUFAF4 | 1031 |
| NDUFV2 | 1878 |
| TIMMDC1 | 5017 |
| NDUFAF1 | 5112 |
| MT-ND4 | 6120 |
| NDUFAF7 | 6191 |
| NDUFB5 | 6290 |
| TMEM126B | 7253 |
| NDUFA9 | 8221 |
| NDUFAF6 | 8803 |
| NDUFA5 | 9374 |
| NUBPL | 9590 |
Pentose phosphate pathway
| 808 | |
|---|---|
| set | Pentose phosphate pathway |
| setSize | 13 |
| pANOVA | 0.00739 |
| s.dist | -0.429 |
| p.adjustANOVA | 0.0282 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| PGLS | -9000 |
| G6PD | -8930 |
| TKT | -8158 |
| PGD | -8059 |
| RPIA | -7209 |
| TALDO1 | -5350 |
| PGM2 | -4124 |
| RBKS | -3847 |
| PRPS1 | -3431 |
| SHPK | 280 |
| RPE | 3613 |
| DERA | 5984 |
| PRPS2 | 9579 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| PGLS | -9000 |
| G6PD | -8930 |
| TKT | -8158 |
| PGD | -8059 |
| RPIA | -7209 |
| TALDO1 | -5350 |
| PGM2 | -4124 |
| RBKS | -3847 |
| PRPS1 | -3431 |
| SHPK | 280 |
| RPE | 3613 |
| DERA | 5984 |
| PRPS2 | 9579 |
Signaling by ROBO receptors
| 1131 | |
|---|---|
| set | Signaling by ROBO receptors |
| setSize | 202 |
| pANOVA | 8.29e-26 |
| s.dist | -0.428 |
| p.adjustANOVA | 4.53e-24 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| MAGOH | -9181 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| MAGOH | -9181 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| PSMB6 | -8981 |
| RPS3 | -8980 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| PSMD2 | -8924 |
| RPS27A | -8920 |
| PSMB7 | -8904 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| ELOB | -8853 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| ROBO3 | -8735 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| PSMD3 | -8663 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| PSMD9 | -8602 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| PSMB5 | -8532 |
| RPS15 | -8520 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| RPL19 | -8396 |
| NCK2 | -8344 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| PSMD4 | -7754 |
| PSMC3 | -7739 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| PFN1 | -7640 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| EIF4A3 | -7329 |
| RPL4 | -7296 |
| RPL24 | -7262 |
| PSMD13 | -7228 |
| SEM1 | -7202 |
| PSMD8 | -7189 |
| LDB1 | -7150 |
| PSMC5 | -6997 |
| PSMC4 | -6969 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| NTN1 | -6928 |
| UBB | -6926 |
| EIF4G1 | -6857 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| CXCR4 | -6436 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| PSMB10 | -6361 |
| PSMB4 | -6256 |
| PRKACA | -6194 |
| ZSWIM8 | -6186 |
| PSMB1 | -5932 |
| RPL28 | -5853 |
| RPL26L1 | -5693 |
| PAK4 | -5598 |
| VASP | -5543 |
| PSMB3 | -5495 |
| PSMF1 | -5464 |
| PSMA7 | -5363 |
| RPL23A | -5130 |
| ABL1 | -5017 |
| RBM8A | -4969 |
| RPL39L | -4904 |
| SLIT3 | -4848 |
| RPS4X | -4837 |
| PAK6 | -4779 |
| RPS24 | -4741 |
| RPL9 | -4555 |
| PRKCA | -4463 |
| RPS3A | -4198 |
| UBC | -4156 |
| SLIT1 | -3712 |
| RNPS1 | -3636 |
| DAG1 | -3623 |
| RPL6 | -3572 |
| MYO9B | -3514 |
| SRC | -3482 |
| CAP1 | -3311 |
| CLASP1 | -3191 |
| GPC1 | -3166 |
| PFN2 | -3003 |
| CASC3 | -2260 |
| NELL2 | -2064 |
| PAK3 | -2062 |
| PSMA2 | -1900 |
| PSMC1 | -1755 |
| UPF3A | -1277 |
| ELOC | -589 |
| RPS26 | -480 |
| PSMD6 | -394 |
| RHOA | -387 |
| PRKAR2A | -370 |
| AKAP5 | -329 |
| EVL | -61 |
| PSMB2 | 283 |
| PSMA1 | 433 |
| PSME3 | 483 |
| RPL22L1 | 543 |
| ABL2 | 1181 |
| ROBO1 | 1551 |
| RPS4Y1 | 1781 |
| ARHGAP39 | 1880 |
| RBX1 | 1884 |
| GSPT2 | 2014 |
| PSMA8 | 2647 |
| PSMD7 | 2722 |
| PABPC1 | 2767 |
| SOS2 | 2914 |
| PSMB9 | 2928 |
| MSI1 | 3005 |
| PRKACB | 3080 |
| PSME1 | 3205 |
| NCK1 | 3472 |
| RAC1 | 3573 |
| RPSA | 3639 |
| PSMB8 | 3659 |
| PSMC2 | 4032 |
| ETF1 | 4209 |
| PSMD1 | 4367 |
| PSMA5 | 4469 |
| PAK2 | 4813 |
| PSMD14 | 4877 |
| PSMD10 | 5090 |
| SRGAP2 | 5164 |
| LHX4 | 5171 |
| CLASP2 | 5297 |
| CDC42 | 5814 |
| ENAH | 6430 |
| UPF3B | 7058 |
| PPP3CB | 7305 |
| PAK1 | 7324 |
| MAGOHB | 7470 |
| PSMD11 | 8028 |
| HOXA2 | 8470 |
| PSMA6 | 8998 |
| GSPT1 | 9073 |
| PSMC6 | 9298 |
| SRGAP1 | 9683 |
| CUL2 | 9832 |
| RPS27L | 10040 |
| PSME2 | 10300 |
| PSME4 | 10448 |
| UPF2 | 10733 |
| SRGAP3 | 10970 |
| NRP1 | 10971 |
| RPL3L | 10975 |
| NCBP2 | 11197 |
| SOS1 | 11461 |
| PSMA4 | 11467 |
| NCBP1 | 11649 |
| USP33 | 11673 |
| PSMD12 | 12185 |
| PSMD5 | 12195 |
| PSMA3 | 12678 |
Interleukin-2 signaling
| 562 | |
|---|---|
| set | Interleukin-2 signaling |
| setSize | 11 |
| pANOVA | 0.0141 |
| s.dist | -0.428 |
| p.adjustANOVA | 0.0462 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IL2RB | -9144 |
| PTK2B | -7693 |
| JAK1 | -6049 |
| STAT5A | -5628 |
| STAT5B | -5574 |
| SYK | -4528 |
| LCK | -3519 |
| JAK3 | -3013 |
| IL2RG | 2279 |
| SHC1 | 4352 |
| IL2RA | 5987 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IL2RB | -9144 |
| PTK2B | -7693 |
| JAK1 | -6049 |
| STAT5A | -5628 |
| STAT5B | -5574 |
| SYK | -4528 |
| LCK | -3519 |
| JAK3 | -3013 |
| IL2RG | 2279 |
| SHC1 | 4352 |
| IL2RA | 5987 |
RHO GTPases Activate NADPH Oxidases
| 888 | |
|---|---|
| set | RHO GTPases Activate NADPH Oxidases |
| setSize | 21 |
| pANOVA | 0.000722 |
| s.dist | -0.426 |
| p.adjustANOVA | 0.0053 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MAPK3 | -9270 |
| PIN1 | -8803 |
| RAC2 | -7531 |
| CYBA | -7441 |
| S100A9 | -7252 |
| NCF4 | -6937 |
| PRKCZ | -6281 |
| S100A8 | -5506 |
| PRKCB | -4714 |
| PRKCA | -4463 |
| PRKCD | -3494 |
| NOXA1 | -3219 |
| NCF1 | -2906 |
| NCF2 | -2232 |
| MAPK1 | -1557 |
| MAPK14 | -1105 |
| CYBB | 1635 |
| MAPK11 | 1946 |
| RAC1 | 3573 |
| PIK3R4 | 5404 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MAPK3 | -9270 |
| PIN1 | -8803 |
| RAC2 | -7531 |
| CYBA | -7441 |
| S100A9 | -7252 |
| NCF4 | -6937 |
| PRKCZ | -6281 |
| S100A8 | -5506 |
| PRKCB | -4714 |
| PRKCA | -4463 |
| PRKCD | -3494 |
| NOXA1 | -3219 |
| NCF1 | -2906 |
| NCF2 | -2232 |
| MAPK1 | -1557 |
| MAPK14 | -1105 |
| CYBB | 1635 |
| MAPK11 | 1946 |
| RAC1 | 3573 |
| PIK3R4 | 5404 |
| PIK3C3 | 8433 |
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
| 539 | |
|---|---|
| set | Insertion of tail-anchored proteins into the endoplasmic reticulum membrane |
| setSize | 22 |
| pANOVA | 0.00055 |
| s.dist | -0.425 |
| p.adjustANOVA | 0.00429 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| GET3 | -8952 |
| EMD | -8553 |
| UBE2J2 | -8440 |
| UBL4A | -8274 |
| GET1 | -8224 |
| SEC61B | -8197 |
| STX5 | -7587 |
| BAG6 | -7488 |
| HMOX1 | -6615 |
| APP | -6325 |
| STX1A | -5161 |
| CAMLG | -4577 |
| SERP1 | -4568 |
| GET4 | -4482 |
| PRNP | -2029 |
| SGTA | -1993 |
| VAMP2 | -377 |
| VAPA | 572 |
| ALDH3A2 | 6195 |
| SEC61G | 8733 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| GET3 | -8952 |
| EMD | -8553 |
| UBE2J2 | -8440 |
| UBL4A | -8274 |
| GET1 | -8224 |
| SEC61B | -8197 |
| STX5 | -7587 |
| BAG6 | -7488 |
| HMOX1 | -6615 |
| APP | -6325 |
| STX1A | -5161 |
| CAMLG | -4577 |
| SERP1 | -4568 |
| GET4 | -4482 |
| PRNP | -2029 |
| SGTA | -1993 |
| VAMP2 | -377 |
| VAPA | 572 |
| ALDH3A2 | 6195 |
| SEC61G | 8733 |
| CYB5A | 10232 |
| OTOF | 11616 |
Gluconeogenesis
| 452 | |
|---|---|
| set | Gluconeogenesis |
| setSize | 28 |
| pANOVA | 0.000102 |
| s.dist | -0.424 |
| p.adjustANOVA | 0.00108 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| PC | -8958 |
| GAPDH | -8833 |
| PGAM1 | -8272 |
| ENO1 | -8125 |
| TPI1 | -8032 |
| MDH2 | -7721 |
| ALDOA | -7234 |
| GPI | -7056 |
| SLC25A11 | -6833 |
| SLC25A1 | -6216 |
| SLC37A2 | -6184 |
| SLC25A10 | -5811 |
| ENO3 | -5791 |
| G6PC3 | -4739 |
| PGK1 | -4698 |
| FBP1 | -3195 |
| SLC37A1 | -356 |
| MDH1 | 348 |
| SLC37A4 | 566 |
| SLC25A13 | 702 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| PC | -8958 |
| GAPDH | -8833 |
| PGAM1 | -8272 |
| ENO1 | -8125 |
| TPI1 | -8032 |
| MDH2 | -7721 |
| ALDOA | -7234 |
| GPI | -7056 |
| SLC25A11 | -6833 |
| SLC25A1 | -6216 |
| SLC37A2 | -6184 |
| SLC25A10 | -5811 |
| ENO3 | -5791 |
| G6PC3 | -4739 |
| PGK1 | -4698 |
| FBP1 | -3195 |
| SLC37A1 | -356 |
| MDH1 | 348 |
| SLC37A4 | 566 |
| SLC25A13 | 702 |
| GOT2 | 1116 |
| ALDOC | 1152 |
| ALDOB | 2063 |
| SLC25A12 | 2691 |
| G6PC | 3272 |
| ENO2 | 3423 |
| PCK2 | 4603 |
| GOT1 | 6464 |
Common Pathway of Fibrin Clot Formation
| 201 | |
|---|---|
| set | Common Pathway of Fibrin Clot Formation |
| setSize | 14 |
| pANOVA | 0.00607 |
| s.dist | -0.424 |
| p.adjustANOVA | 0.0247 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| PRTN3 | -9019 |
| PF4 | -8316 |
| F13A1 | -7978 |
| CD177 | -7523 |
| PROCR | -6370 |
| PROS1 | -6369 |
| PROC | -3237 |
| THBD | -2999 |
| PF4V1 | -1873 |
| SERPINE2 | -676 |
| F2R | 376 |
| F5 | 2690 |
| F8 | 3561 |
| SERPIND1 | 6971 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| PRTN3 | -9019 |
| PF4 | -8316 |
| F13A1 | -7978 |
| CD177 | -7523 |
| PROCR | -6370 |
| PROS1 | -6369 |
| PROC | -3237 |
| THBD | -2999 |
| PF4V1 | -1873 |
| SERPINE2 | -676 |
| F2R | 376 |
| F5 | 2690 |
| F8 | 3561 |
| SERPIND1 | 6971 |
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
| 1007 | |
|---|---|
| set | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| setSize | 124 |
| pANOVA | 4.77e-16 |
| s.dist | -0.422 |
| p.adjustANOVA | 1.71e-14 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MT-ATP8 | -9237 |
| NDUFA13 | -9149 |
| ATP5ME | -9114 |
| NDUFA2 | -9096 |
| ATP5MG | -9055 |
| UQCR11 | -9022 |
| NDUFB2 | -8996 |
| ATP5F1D | -8993 |
| ATP5MF | -8988 |
| TACO1 | -8956 |
| NDUFA1 | -8947 |
| NDUFS6 | -8919 |
| UQCRH | -8905 |
| UQCR10 | -8865 |
| NDUFB10 | -8842 |
| COX6A1 | -8836 |
| NDUFB1 | -8779 |
| COX8A | -8675 |
| ATP5MC2 | -8655 |
| NDUFB9 | -8627 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MT-ATP8 | -9237 |
| NDUFA13 | -9149 |
| ATP5ME | -9114 |
| NDUFA2 | -9096 |
| ATP5MG | -9055 |
| UQCR11 | -9022 |
| NDUFB2 | -8996 |
| ATP5F1D | -8993 |
| ATP5MF | -8988 |
| TACO1 | -8956 |
| NDUFA1 | -8947 |
| NDUFS6 | -8919 |
| UQCRH | -8905 |
| UQCR10 | -8865 |
| NDUFB10 | -8842 |
| COX6A1 | -8836 |
| NDUFB1 | -8779 |
| COX8A | -8675 |
| ATP5MC2 | -8655 |
| NDUFB9 | -8627 |
| NDUFB8 | -8467 |
| NDUFS8 | -8382 |
| NDUFB7 | -8324 |
| COX5B | -8295 |
| MT-ATP6 | -8247 |
| COX7C | -8188 |
| NDUFC2 | -8123 |
| NDUFAF3 | -8118 |
| CYC1 | -8103 |
| NDUFS5 | -8090 |
| MT-CO3 | -8066 |
| COX5A | -7971 |
| NDUFA7 | -7443 |
| MT-ND3 | -7383 |
| NDUFA3 | -7374 |
| COX14 | -7353 |
| ATP5F1E | -7305 |
| UQCRC1 | -7246 |
| ATP5F1A | -7191 |
| COX4I1 | -7122 |
| NDUFS3 | -7081 |
| NDUFS7 | -7074 |
| NDUFB11 | -6957 |
| ATP5MC3 | -6943 |
| ECSIT | -6932 |
| ETFB | -6788 |
| NDUFV1 | -6747 |
| SDHC | -6721 |
| MT-CO2 | -6670 |
| UQCRQ | -6610 |
| COX6B1 | -6332 |
| NDUFA11 | -6299 |
| NDUFA4 | -6086 |
| MT-ND1 | -5890 |
| ACAD9 | -5767 |
| SDHA | -5763 |
| COX7B | -5740 |
| NDUFAB1 | -5641 |
| ATP5PB | -5586 |
| NDUFB4 | -5418 |
| MT-ND2 | -5100 |
| UQCRB | -5080 |
| NDUFA6 | -4947 |
| COX6C | -4849 |
| ATP5F1B | -4642 |
| ATP5PF | -4410 |
| NDUFB3 | -4315 |
| MT-CYB | -4300 |
| NDUFS2 | -4259 |
| NDUFC1 | -4127 |
| MT-ND5 | -3886 |
| TRAP1 | -3852 |
| UCP3 | -3807 |
| UCP2 | -3787 |
| SDHB | -3404 |
| SURF1 | -3295 |
| ATP5PO | -2733 |
| UQCRFS1 | -2671 |
| NDUFV3 | -2226 |
| MT-CO1 | -1832 |
| SLC25A14 | -1568 |
| ATP5MC1 | -1306 |
| UQCRC2 | -1297 |
| ATP5PD | -1292 |
| NDUFA12 | -1259 |
| COX7A2L | -1147 |
| NDUFB6 | -1111 |
| NDUFA10 | -980 |
| NDUFAF5 | -905 |
| NDUFA8 | -468 |
| NDUFS4 | 273 |
| NDUFS1 | 530 |
| NDUFAF2 | 540 |
| MT-ND6 | 682 |
| NDUFAF4 | 1031 |
| COQ10A | 1123 |
| NDUFV2 | 1878 |
| ATP5F1C | 2542 |
| LRPPRC | 4100 |
| PM20D1 | 4221 |
| SCO1 | 4418 |
| TIMMDC1 | 5017 |
| SDHD | 5025 |
| NDUFAF1 | 5112 |
| CYCS | 5334 |
| SCO2 | 6068 |
| MT-ND4 | 6120 |
| NDUFAF7 | 6191 |
| NDUFB5 | 6290 |
| COQ10B | 6721 |
| TMEM126B | 7253 |
| ETFA | 7504 |
| COX11 | 7523 |
| SLC25A27 | 7635 |
| ETFDH | 8052 |
| NDUFA9 | 8221 |
| COX18 | 8740 |
| NDUFAF6 | 8803 |
| COX19 | 9229 |
| COX20 | 9281 |
| NDUFA5 | 9374 |
| NUBPL | 9590 |
| COX16 | 9607 |
| DMAC2L | 11593 |
rRNA processing in the mitochondrion
| 1356 | |
|---|---|
| set | rRNA processing in the mitochondrion |
| setSize | 29 |
| pANOVA | 9.62e-05 |
| s.dist | -0.418 |
| p.adjustANOVA | 0.00103 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MT-ATP8 | -9237 |
| MT-ATP6 | -8247 |
| MT-CO3 | -8066 |
| MT-ND3 | -7383 |
| MT-ND4L | -7200 |
| HSD17B10 | -7145 |
| MT-CO2 | -6670 |
| MT-ND1 | -5890 |
| MT-TV | -5625 |
| MT-TL2 | -5513 |
| MT-ND2 | -5100 |
| ELAC2 | -5058 |
| MT-TM | -4720 |
| MT-TF | -4317 |
| MT-CYB | -4300 |
| MTERF4 | -4095 |
| MT-ND5 | -3886 |
| MRM3 | -2993 |
| MT-RNR1 | -2749 |
| MRM2 | -2590 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MT-ATP8 | -9237 |
| MT-ATP6 | -8247 |
| MT-CO3 | -8066 |
| MT-ND3 | -7383 |
| MT-ND4L | -7200 |
| HSD17B10 | -7145 |
| MT-CO2 | -6670 |
| MT-ND1 | -5890 |
| MT-TV | -5625 |
| MT-TL2 | -5513 |
| MT-ND2 | -5100 |
| ELAC2 | -5058 |
| MT-TM | -4720 |
| MT-TF | -4317 |
| MT-CYB | -4300 |
| MTERF4 | -4095 |
| MT-ND5 | -3886 |
| MRM3 | -2993 |
| MT-RNR1 | -2749 |
| MRM2 | -2590 |
| MRM1 | -2434 |
| MT-TL1 | -2174 |
| MT-CO1 | -1832 |
| MT-RNR2 | -1586 |
| PRORP | 5007 |
| MT-ND4 | 6120 |
| TFB1M | 7599 |
| NSUN4 | 8390 |
| TRMT10C | 9005 |
GAB1 signalosome
| 424 | |
|---|---|
| set | GAB1 signalosome |
| setSize | 15 |
| pANOVA | 0.0051 |
| s.dist | -0.418 |
| p.adjustANOVA | 0.022 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| HBEGF | -8399 |
| AREG | -7998 |
| EREG | -7447 |
| PXN | -7377 |
| CSK | -7235 |
| EGF | -5815 |
| GRB2 | -5369 |
| TGFA | -5356 |
| PIK3R1 | -5262 |
| SRC | -3482 |
| PAG1 | 835 |
| PTPN11 | 977 |
| EPGN | 1789 |
| PIK3CA | 7282 |
| GAB1 | 10166 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HBEGF | -8399 |
| AREG | -7998 |
| EREG | -7447 |
| PXN | -7377 |
| CSK | -7235 |
| EGF | -5815 |
| GRB2 | -5369 |
| TGFA | -5356 |
| PIK3R1 | -5262 |
| SRC | -3482 |
| PAG1 | 835 |
| PTPN11 | 977 |
| EPGN | 1789 |
| PIK3CA | 7282 |
| GAB1 | 10166 |
AKT phosphorylates targets in the nucleus
| 9 | |
|---|---|
| set | AKT phosphorylates targets in the nucleus |
| setSize | 10 |
| pANOVA | 0.0223 |
| s.dist | -0.417 |
| p.adjustANOVA | 0.065 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| AKT1 | -8457 |
| FOXO4 | -8425 |
| AKT2 | -8110 |
| FOXO3 | -6813 |
| FOXO6 | -5750 |
| RPS6KB2 | -3665 |
| FOXO1 | -2811 |
| AKT3 | 2977 |
| NR4A1 | 5792 |
| CREB1 | 6840 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| AKT1 | -8457 |
| FOXO4 | -8425 |
| AKT2 | -8110 |
| FOXO3 | -6813 |
| FOXO6 | -5750 |
| RPS6KB2 | -3665 |
| FOXO1 | -2811 |
| AKT3 | 2977 |
| NR4A1 | 5792 |
| CREB1 | 6840 |
A tetrasaccharide linker sequence is required for GAG synthesis
| 1 | |
|---|---|
| set | A tetrasaccharide linker sequence is required for GAG synthesis |
| setSize | 18 |
| pANOVA | 0.00221 |
| s.dist | -0.417 |
| p.adjustANOVA | 0.0125 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| GPC4 | -8599 |
| XYLT1 | -8163 |
| B3GAT3 | -7628 |
| B3GALT6 | -7527 |
| SDC4 | -6556 |
| VCAN | -5852 |
| XYLT2 | -5595 |
| GPC2 | -4351 |
| DCN | -3528 |
| GPC1 | -3166 |
| B4GALT7 | -2929 |
| B3GAT2 | -960 |
| HSPG2 | 202 |
| SDC2 | 317 |
| SDC3 | 325 |
| CSPG4 | 627 |
| B3GAT1 | 2158 |
| AGRN | 10192 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| GPC4 | -8599 |
| XYLT1 | -8163 |
| B3GAT3 | -7628 |
| B3GALT6 | -7527 |
| SDC4 | -6556 |
| VCAN | -5852 |
| XYLT2 | -5595 |
| GPC2 | -4351 |
| DCN | -3528 |
| GPC1 | -3166 |
| B4GALT7 | -2929 |
| B3GAT2 | -960 |
| HSPG2 | 202 |
| SDC2 | 317 |
| SDC3 | 325 |
| CSPG4 | 627 |
| B3GAT1 | 2158 |
| AGRN | 10192 |
FOXO-mediated transcription of cell death genes
| 372 | |
|---|---|
| set | FOXO-mediated transcription of cell death genes |
| setSize | 16 |
| pANOVA | 0.00399 |
| s.dist | -0.416 |
| p.adjustANOVA | 0.0189 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| FOXO4 | -8425 |
| PINK1 | -8330 |
| STK11 | -7479 |
| BBC3 | -7010 |
| FOXO3 | -6813 |
| CITED2 | -6300 |
| CREBBP | -4757 |
| FASLG | -3132 |
| FOXO1 | -2811 |
| BCL6 | -2115 |
| NFYC | -1310 |
| BCL2L11 | -832 |
| NFYA | 89 |
| EP300 | 2511 |
| NFYB | 5436 |
| DDIT3 | 6097 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| FOXO4 | -8425 |
| PINK1 | -8330 |
| STK11 | -7479 |
| BBC3 | -7010 |
| FOXO3 | -6813 |
| CITED2 | -6300 |
| CREBBP | -4757 |
| FASLG | -3132 |
| FOXO1 | -2811 |
| BCL6 | -2115 |
| NFYC | -1310 |
| BCL2L11 | -832 |
| NFYA | 89 |
| EP300 | 2511 |
| NFYB | 5436 |
| DDIT3 | 6097 |
HIV elongation arrest and recovery
| 486 | |
|---|---|
| set | HIV elongation arrest and recovery |
| setSize | 32 |
| pANOVA | 4.99e-05 |
| s.dist | -0.414 |
| p.adjustANOVA | 0.000592 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| POLR2L | -9269 |
| POLR2E | -9009 |
| NELFB | -8864 |
| ELOB | -8853 |
| CDK9 | -8696 |
| POLR2F | -8657 |
| POLR2G | -8638 |
| CTDP1 | -8450 |
| POLR2I | -8445 |
| POLR2J | -8226 |
| GTF2F1 | -7647 |
| POLR2H | -7192 |
| ELL | -6345 |
| SSRP1 | -5315 |
| SUPT5H | -5198 |
| NELFE | -5184 |
| POLR2C | -4979 |
| SUPT4H1 | -4193 |
| POLR2A | -1960 |
| NELFA | -1628 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| POLR2L | -9269 |
| POLR2E | -9009 |
| NELFB | -8864 |
| ELOB | -8853 |
| CDK9 | -8696 |
| POLR2F | -8657 |
| POLR2G | -8638 |
| CTDP1 | -8450 |
| POLR2I | -8445 |
| POLR2J | -8226 |
| GTF2F1 | -7647 |
| POLR2H | -7192 |
| ELL | -6345 |
| SSRP1 | -5315 |
| SUPT5H | -5198 |
| NELFE | -5184 |
| POLR2C | -4979 |
| SUPT4H1 | -4193 |
| POLR2A | -1960 |
| NELFA | -1628 |
| ELOC | -589 |
| NELFCD | -430 |
| GTF2F2 | 453 |
| POLR2B | 1553 |
| ELOA | 1830 |
| SUPT16H | 1885 |
| CCNT1 | 2384 |
| POLR2D | 5190 |
| TCEA1 | 7496 |
| POLR2K | 7850 |
| CCNK | 8825 |
| CCNT2 | 10538 |
Pausing and recovery of HIV elongation
| 806 | |
|---|---|
| set | Pausing and recovery of HIV elongation |
| setSize | 32 |
| pANOVA | 4.99e-05 |
| s.dist | -0.414 |
| p.adjustANOVA | 0.000592 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| POLR2L | -9269 |
| POLR2E | -9009 |
| NELFB | -8864 |
| ELOB | -8853 |
| CDK9 | -8696 |
| POLR2F | -8657 |
| POLR2G | -8638 |
| CTDP1 | -8450 |
| POLR2I | -8445 |
| POLR2J | -8226 |
| GTF2F1 | -7647 |
| POLR2H | -7192 |
| ELL | -6345 |
| SSRP1 | -5315 |
| SUPT5H | -5198 |
| NELFE | -5184 |
| POLR2C | -4979 |
| SUPT4H1 | -4193 |
| POLR2A | -1960 |
| NELFA | -1628 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| POLR2L | -9269 |
| POLR2E | -9009 |
| NELFB | -8864 |
| ELOB | -8853 |
| CDK9 | -8696 |
| POLR2F | -8657 |
| POLR2G | -8638 |
| CTDP1 | -8450 |
| POLR2I | -8445 |
| POLR2J | -8226 |
| GTF2F1 | -7647 |
| POLR2H | -7192 |
| ELL | -6345 |
| SSRP1 | -5315 |
| SUPT5H | -5198 |
| NELFE | -5184 |
| POLR2C | -4979 |
| SUPT4H1 | -4193 |
| POLR2A | -1960 |
| NELFA | -1628 |
| ELOC | -589 |
| NELFCD | -430 |
| GTF2F2 | 453 |
| POLR2B | 1553 |
| ELOA | 1830 |
| SUPT16H | 1885 |
| CCNT1 | 2384 |
| POLR2D | 5190 |
| TCEA1 | 7496 |
| POLR2K | 7850 |
| CCNK | 8825 |
| CCNT2 | 10538 |
CDC6 association with the ORC:origin complex
| 127 | |
|---|---|
| set | CDC6 association with the ORC:origin complex |
| setSize | 11 |
| pANOVA | 0.0175 |
| s.dist | 0.414 |
| p.adjustANOVA | 0.0538 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| ORC3 | 10696 |
| ORC5 | 10247 |
| ORC4 | 8681 |
| MCM8 | 7881 |
| ORC2 | 7759 |
| E2F3 | 7233 |
| E2F1 | 7184 |
| ORC6 | 5069 |
| CDC6 | 3827 |
| ORC1 | 1071 |
| E2F2 | 127 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ORC3 | 10696 |
| ORC5 | 10247 |
| ORC4 | 8681 |
| MCM8 | 7881 |
| ORC2 | 7759 |
| E2F3 | 7233 |
| E2F1 | 7184 |
| ORC6 | 5069 |
| CDC6 | 3827 |
| ORC1 | 1071 |
| E2F2 | 127 |
Membrane binding and targetting of GAG proteins
| 633 | |
|---|---|
| set | Membrane binding and targetting of GAG proteins |
| setSize | 13 |
| pANOVA | 0.00989 |
| s.dist | -0.413 |
| p.adjustANOVA | 0.0346 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| VPS28 | -8764 |
| MVB12A | -8489 |
| UBA52 | -8454 |
| VPS37B | -7260 |
| UBB | -6926 |
| UBAP1 | -5567 |
| UBC | -4156 |
| VPS37C | -971 |
| MVB12B | -724 |
| TSG101 | 4524 |
| NMT2 | 9221 |
| VPS37A | 10118 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| VPS28 | -8764 |
| MVB12A | -8489 |
| UBA52 | -8454 |
| VPS37B | -7260 |
| UBB | -6926 |
| UBAP1 | -5567 |
| UBC | -4156 |
| VPS37C | -971 |
| MVB12B | -724 |
| TSG101 | 4524 |
| NMT2 | 9221 |
| VPS37A | 10118 |
Synthesis And Processing Of GAG, GAGPOL Polyproteins
| 1163 | |
|---|---|
| set | Synthesis And Processing Of GAG, GAGPOL Polyproteins |
| setSize | 13 |
| pANOVA | 0.00989 |
| s.dist | -0.413 |
| p.adjustANOVA | 0.0346 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| VPS28 | -8764 |
| MVB12A | -8489 |
| UBA52 | -8454 |
| VPS37B | -7260 |
| UBB | -6926 |
| UBAP1 | -5567 |
| UBC | -4156 |
| VPS37C | -971 |
| MVB12B | -724 |
| TSG101 | 4524 |
| NMT2 | 9221 |
| VPS37A | 10118 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| VPS28 | -8764 |
| MVB12A | -8489 |
| UBA52 | -8454 |
| VPS37B | -7260 |
| UBB | -6926 |
| UBAP1 | -5567 |
| UBC | -4156 |
| VPS37C | -971 |
| MVB12B | -724 |
| TSG101 | 4524 |
| NMT2 | 9221 |
| VPS37A | 10118 |
Downregulation of ERBB2:ERBB3 signaling
| 305 | |
|---|---|
| set | Downregulation of ERBB2:ERBB3 signaling |
| setSize | 12 |
| pANOVA | 0.0136 |
| s.dist | -0.411 |
| p.adjustANOVA | 0.0448 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| AKT1 | -8457 |
| UBA52 | -8454 |
| AKT2 | -8110 |
| UBB | -6926 |
| NRG1 | -6772 |
| UBC | -4156 |
| ERBB2 | -3699 |
| RNF41 | -578 |
| AKT3 | 2977 |
| ERBB3 | 7242 |
| USP8 | 12512 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| AKT1 | -8457 |
| UBA52 | -8454 |
| AKT2 | -8110 |
| UBB | -6926 |
| NRG1 | -6772 |
| UBC | -4156 |
| ERBB2 | -3699 |
| RNF41 | -578 |
| AKT3 | 2977 |
| ERBB3 | 7242 |
| USP8 | 12512 |
p75NTR signals via NF-kB
| 1352 | |
|---|---|
| set | p75NTR signals via NF-kB |
| setSize | 15 |
| pANOVA | 0.00586 |
| s.dist | -0.411 |
| p.adjustANOVA | 0.0245 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| SQSTM1 | -8744 |
| UBA52 | -8454 |
| NFKBIA | -8313 |
| IRAK1 | -7896 |
| RELA | -7350 |
| UBB | -6926 |
| UBC | -4156 |
| NFKB1 | -2798 |
| RIPK2 | -515 |
| IKBKB | -167 |
| MYD88 | 3690 |
| PRKCI | 4152 |
| TRAF6 | 6905 |
| NGFR | 7911 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| SQSTM1 | -8744 |
| UBA52 | -8454 |
| NFKBIA | -8313 |
| IRAK1 | -7896 |
| RELA | -7350 |
| UBB | -6926 |
| UBC | -4156 |
| NFKB1 | -2798 |
| RIPK2 | -515 |
| IKBKB | -167 |
| MYD88 | 3690 |
| PRKCI | 4152 |
| TRAF6 | 6905 |
| NGFR | 7911 |
PKA activation
| 794 | |
|---|---|
| set | PKA activation |
| setSize | 15 |
| pANOVA | 0.00626 |
| s.dist | -0.408 |
| p.adjustANOVA | 0.0255 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| ADCY9 | -8692 |
| PRKAR2B | -7977 |
| NBEA | -6564 |
| ADCY3 | -6347 |
| PRKACA | -6194 |
| PRKAR1B | -5101 |
| ADCY5 | -4691 |
| ADCY6 | -4556 |
| ADCY7 | -4056 |
| PRKAR2A | -370 |
| PRKAR1A | 1283 |
| ADCY4 | 1838 |
| PRKACB | 3080 |
| ADCY2 | 3640 |
| CALM1 | 3673 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ADCY9 | -8692 |
| PRKAR2B | -7977 |
| NBEA | -6564 |
| ADCY3 | -6347 |
| PRKACA | -6194 |
| PRKAR1B | -5101 |
| ADCY5 | -4691 |
| ADCY6 | -4556 |
| ADCY7 | -4056 |
| PRKAR2A | -370 |
| PRKAR1A | 1283 |
| ADCY4 | 1838 |
| PRKACB | 3080 |
| ADCY2 | 3640 |
| CALM1 | 3673 |
Mucopolysaccharidoses
| 684 | |
|---|---|
| set | Mucopolysaccharidoses |
| setSize | 11 |
| pANOVA | 0.0193 |
| s.dist | -0.407 |
| p.adjustANOVA | 0.0575 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SGSH | -8871 |
| NAGLU | -7870 |
| GUSB | -6463 |
| IDUA | -5903 |
| GLB1 | -4294 |
| GALNS | -3866 |
| IDS | -2509 |
| GNS | -1497 |
| HGSNAT | -756 |
| ARSB | 1964 |
| HYAL1 | 9992 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SGSH | -8871 |
| NAGLU | -7870 |
| GUSB | -6463 |
| IDUA | -5903 |
| GLB1 | -4294 |
| GALNS | -3866 |
| IDS | -2509 |
| GNS | -1497 |
| HGSNAT | -756 |
| ARSB | 1964 |
| HYAL1 | 9992 |
Downregulation of ERBB2 signaling
| 304 | |
|---|---|
| set | Downregulation of ERBB2 signaling |
| setSize | 24 |
| pANOVA | 0.000556 |
| s.dist | -0.407 |
| p.adjustANOVA | 0.00429 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| STUB1 | -8915 |
| MATK | -8705 |
| CDC37 | -8536 |
| AKT1 | -8457 |
| UBA52 | -8454 |
| HBEGF | -8399 |
| AKT2 | -8110 |
| EREG | -7447 |
| UBB | -6926 |
| NRG1 | -6772 |
| EGF | -5815 |
| PTPN18 | -4671 |
| PTPN12 | -4229 |
| UBC | -4156 |
| ERBB2 | -3699 |
| NRG4 | -1472 |
| RNF41 | -578 |
| AKT3 | 2977 |
| ERBIN | 6882 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS27A | -8920 |
| STUB1 | -8915 |
| MATK | -8705 |
| CDC37 | -8536 |
| AKT1 | -8457 |
| UBA52 | -8454 |
| HBEGF | -8399 |
| AKT2 | -8110 |
| EREG | -7447 |
| UBB | -6926 |
| NRG1 | -6772 |
| EGF | -5815 |
| PTPN18 | -4671 |
| PTPN12 | -4229 |
| UBC | -4156 |
| ERBB2 | -3699 |
| NRG4 | -1472 |
| RNF41 | -578 |
| AKT3 | 2977 |
| ERBIN | 6882 |
| ERBB3 | 7242 |
| HSP90AA1 | 7453 |
| CUL5 | 11748 |
| USP8 | 12512 |
Uptake and function of anthrax toxins
| 1307 | |
|---|---|
| set | Uptake and function of anthrax toxins |
| setSize | 10 |
| pANOVA | 0.0263 |
| s.dist | -0.406 |
| p.adjustANOVA | 0.073 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| FURIN | -9250 |
| MAP2K2 | -9200 |
| MAP2K7 | -7876 |
| ANTXR2 | -7711 |
| MAP2K1 | -7362 |
| MAP2K3 | -6806 |
| MAP2K4 | 1361 |
| CALM1 | 3673 |
| MAP2K6 | 6765 |
| PDCD6IP | 9241 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| FURIN | -9250 |
| MAP2K2 | -9200 |
| MAP2K7 | -7876 |
| ANTXR2 | -7711 |
| MAP2K1 | -7362 |
| MAP2K3 | -6806 |
| MAP2K4 | 1361 |
| CALM1 | 3673 |
| MAP2K6 | 6765 |
| PDCD6IP | 9241 |
Constitutive Signaling by NOTCH1 HD Domain Mutants
| 211 | |
|---|---|
| set | Constitutive Signaling by NOTCH1 HD Domain Mutants |
| setSize | 14 |
| pANOVA | 0.00862 |
| s.dist | -0.405 |
| p.adjustANOVA | 0.0314 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| NEURL1B | -9191 |
| RPS27A | -8920 |
| UBA52 | -8454 |
| JAG1 | -6938 |
| UBB | -6926 |
| NOTCH1 | -5725 |
| UBC | -4156 |
| MIB2 | -3856 |
| DLL1 | -759 |
| MIB1 | 335 |
| ADAM10 | 1007 |
| JAG2 | 2060 |
| ADAM17 | 6118 |
| NEURL1 | 7439 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| NEURL1B | -9191 |
| RPS27A | -8920 |
| UBA52 | -8454 |
| JAG1 | -6938 |
| UBB | -6926 |
| NOTCH1 | -5725 |
| UBC | -4156 |
| MIB2 | -3856 |
| DLL1 | -759 |
| MIB1 | 335 |
| ADAM10 | 1007 |
| JAG2 | 2060 |
| ADAM17 | 6118 |
| NEURL1 | 7439 |
Signaling by NOTCH1 HD Domain Mutants in Cancer
| 1111 | |
|---|---|
| set | Signaling by NOTCH1 HD Domain Mutants in Cancer |
| setSize | 14 |
| pANOVA | 0.00862 |
| s.dist | -0.405 |
| p.adjustANOVA | 0.0314 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| NEURL1B | -9191 |
| RPS27A | -8920 |
| UBA52 | -8454 |
| JAG1 | -6938 |
| UBB | -6926 |
| NOTCH1 | -5725 |
| UBC | -4156 |
| MIB2 | -3856 |
| DLL1 | -759 |
| MIB1 | 335 |
| ADAM10 | 1007 |
| JAG2 | 2060 |
| ADAM17 | 6118 |
| NEURL1 | 7439 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| NEURL1B | -9191 |
| RPS27A | -8920 |
| UBA52 | -8454 |
| JAG1 | -6938 |
| UBB | -6926 |
| NOTCH1 | -5725 |
| UBC | -4156 |
| MIB2 | -3856 |
| DLL1 | -759 |
| MIB1 | 335 |
| ADAM10 | 1007 |
| JAG2 | 2060 |
| ADAM17 | 6118 |
| NEURL1 | 7439 |
Acetylcholine Neurotransmitter Release Cycle
| 30 | |
|---|---|
| set | Acetylcholine Neurotransmitter Release Cycle |
| setSize | 11 |
| pANOVA | 0.0199 |
| s.dist | -0.405 |
| p.adjustANOVA | 0.0589 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| PPFIA3 | -8795 |
| RAB3A | -8285 |
| TSPOAP1 | -7286 |
| CPLX1 | -6357 |
| UNC13B | -6238 |
| STXBP1 | -6138 |
| STX1A | -5161 |
| VAMP2 | -377 |
| PPFIA1 | 3795 |
| SYT1 | 6745 |
| PPFIA4 | 8264 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| PPFIA3 | -8795 |
| RAB3A | -8285 |
| TSPOAP1 | -7286 |
| CPLX1 | -6357 |
| UNC13B | -6238 |
| STXBP1 | -6138 |
| STX1A | -5161 |
| VAMP2 | -377 |
| PPFIA1 | 3795 |
| SYT1 | 6745 |
| PPFIA4 | 8264 |
Respiratory electron transport
| 1006 | |
|---|---|
| set | Respiratory electron transport |
| setSize | 101 |
| pANOVA | 2.67e-12 |
| s.dist | -0.403 |
| p.adjustANOVA | 7.58e-11 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| NDUFA13 | -9149 |
| NDUFA2 | -9096 |
| UQCR11 | -9022 |
| NDUFB2 | -8996 |
| TACO1 | -8956 |
| NDUFA1 | -8947 |
| NDUFS6 | -8919 |
| UQCRH | -8905 |
| UQCR10 | -8865 |
| NDUFB10 | -8842 |
| COX6A1 | -8836 |
| NDUFB1 | -8779 |
| COX8A | -8675 |
| NDUFB9 | -8627 |
| NDUFB8 | -8467 |
| NDUFS8 | -8382 |
| NDUFB7 | -8324 |
| COX5B | -8295 |
| COX7C | -8188 |
| NDUFC2 | -8123 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| NDUFA13 | -9149 |
| NDUFA2 | -9096 |
| UQCR11 | -9022 |
| NDUFB2 | -8996 |
| TACO1 | -8956 |
| NDUFA1 | -8947 |
| NDUFS6 | -8919 |
| UQCRH | -8905 |
| UQCR10 | -8865 |
| NDUFB10 | -8842 |
| COX6A1 | -8836 |
| NDUFB1 | -8779 |
| COX8A | -8675 |
| NDUFB9 | -8627 |
| NDUFB8 | -8467 |
| NDUFS8 | -8382 |
| NDUFB7 | -8324 |
| COX5B | -8295 |
| COX7C | -8188 |
| NDUFC2 | -8123 |
| NDUFAF3 | -8118 |
| CYC1 | -8103 |
| NDUFS5 | -8090 |
| MT-CO3 | -8066 |
| COX5A | -7971 |
| NDUFA7 | -7443 |
| MT-ND3 | -7383 |
| NDUFA3 | -7374 |
| COX14 | -7353 |
| UQCRC1 | -7246 |
| COX4I1 | -7122 |
| NDUFS3 | -7081 |
| NDUFS7 | -7074 |
| NDUFB11 | -6957 |
| ECSIT | -6932 |
| ETFB | -6788 |
| NDUFV1 | -6747 |
| SDHC | -6721 |
| MT-CO2 | -6670 |
| UQCRQ | -6610 |
| COX6B1 | -6332 |
| NDUFA11 | -6299 |
| NDUFA4 | -6086 |
| MT-ND1 | -5890 |
| ACAD9 | -5767 |
| SDHA | -5763 |
| COX7B | -5740 |
| NDUFAB1 | -5641 |
| NDUFB4 | -5418 |
| MT-ND2 | -5100 |
| UQCRB | -5080 |
| NDUFA6 | -4947 |
| COX6C | -4849 |
| NDUFB3 | -4315 |
| MT-CYB | -4300 |
| NDUFS2 | -4259 |
| NDUFC1 | -4127 |
| MT-ND5 | -3886 |
| TRAP1 | -3852 |
| SDHB | -3404 |
| SURF1 | -3295 |
| UQCRFS1 | -2671 |
| NDUFV3 | -2226 |
| MT-CO1 | -1832 |
| UQCRC2 | -1297 |
| NDUFA12 | -1259 |
| COX7A2L | -1147 |
| NDUFB6 | -1111 |
| NDUFA10 | -980 |
| NDUFAF5 | -905 |
| NDUFA8 | -468 |
| NDUFS4 | 273 |
| NDUFS1 | 530 |
| NDUFAF2 | 540 |
| MT-ND6 | 682 |
| NDUFAF4 | 1031 |
| COQ10A | 1123 |
| NDUFV2 | 1878 |
| LRPPRC | 4100 |
| SCO1 | 4418 |
| TIMMDC1 | 5017 |
| SDHD | 5025 |
| NDUFAF1 | 5112 |
| CYCS | 5334 |
| SCO2 | 6068 |
| MT-ND4 | 6120 |
| NDUFAF7 | 6191 |
| NDUFB5 | 6290 |
| COQ10B | 6721 |
| TMEM126B | 7253 |
| ETFA | 7504 |
| COX11 | 7523 |
| ETFDH | 8052 |
| NDUFA9 | 8221 |
| COX18 | 8740 |
| NDUFAF6 | 8803 |
| COX19 | 9229 |
| COX20 | 9281 |
| NDUFA5 | 9374 |
| NUBPL | 9590 |
| COX16 | 9607 |
Plasma lipoprotein clearance
| 826 | |
|---|---|
| set | Plasma lipoprotein clearance |
| setSize | 29 |
| pANOVA | 0.000177 |
| s.dist | -0.402 |
| p.adjustANOVA | 0.00169 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| AP2M1 | -9075 |
| SCARB1 | -9050 |
| APOBR | -8024 |
| NR1H3 | -8011 |
| AP2S1 | -7871 |
| NR1H2 | -7174 |
| MYLIP | -7031 |
| AP2A2 | -6809 |
| AP2A1 | -6392 |
| CLTA | -6017 |
| LSR | -4422 |
| AMN | -3063 |
| APOE | -2579 |
| CUBN | -2516 |
| VLDLR | -2494 |
| CES3 | -2112 |
| LIPA | -2080 |
| SOAT1 | -1946 |
| CLTC | -1627 |
| AP2B1 | -1491 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| AP2M1 | -9075 |
| SCARB1 | -9050 |
| APOBR | -8024 |
| NR1H3 | -8011 |
| AP2S1 | -7871 |
| NR1H2 | -7174 |
| MYLIP | -7031 |
| AP2A2 | -6809 |
| AP2A1 | -6392 |
| CLTA | -6017 |
| LSR | -4422 |
| AMN | -3063 |
| APOE | -2579 |
| CUBN | -2516 |
| VLDLR | -2494 |
| CES3 | -2112 |
| LIPA | -2080 |
| SOAT1 | -1946 |
| CLTC | -1627 |
| AP2B1 | -1491 |
| LIPC | -1245 |
| HDLBP | -725 |
| NPC1 | -451 |
| LDLRAP1 | -353 |
| NCEH1 | 257 |
| NPC2 | 985 |
| SOAT2 | 4902 |
| APOC4 | 7890 |
| LDLR | 11012 |
rRNA processing
| 1355 | |
|---|---|
| set | rRNA processing |
| setSize | 219 |
| pANOVA | 1.92e-24 |
| s.dist | -0.4 |
| p.adjustANOVA | 8.75e-23 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| MT-ATP8 | -9237 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| TSR3 | -9119 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| FBL | -9080 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| MT-ATP8 | -9237 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| TSR3 | -9119 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| FBL | -9080 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| EXOSC7 | -8983 |
| RPS3 | -8980 |
| PES1 | -8968 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| WDR46 | -8946 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| TRMT112 | -8899 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| BOP1 | -8551 |
| RPS15 | -8520 |
| DDX49 | -8519 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| MT-ATP6 | -8247 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| CSNK1D | -8192 |
| RRP9 | -8183 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| MT-CO3 | -8066 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| RPP21 | -7716 |
| NHP2 | -7601 |
| NOP10 | -7526 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| MT-ND3 | -7383 |
| EXOSC5 | -7321 |
| RPL4 | -7296 |
| PWP2 | -7275 |
| RPL24 | -7262 |
| SNU13 | -7206 |
| MT-ND4L | -7200 |
| HSD17B10 | -7145 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| NOP2 | -6828 |
| MT-CO2 | -6670 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| BYSL | -6551 |
| TBL3 | -6536 |
| EXOSC4 | -6453 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| MT-ND1 | -5890 |
| RPL28 | -5853 |
| IMP4 | -5773 |
| RPL26L1 | -5693 |
| MT-TV | -5625 |
| MT-TL2 | -5513 |
| IMP3 | -5241 |
| NOB1 | -5240 |
| RRP36 | -5194 |
| RPL23A | -5130 |
| MT-ND2 | -5100 |
| ELAC2 | -5058 |
| CSNK1E | -5049 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| EXOSC2 | -4827 |
| RPS24 | -4741 |
| RRP7A | -4721 |
| MT-TM | -4720 |
| LAS1L | -4647 |
| RPL9 | -4555 |
| NCL | -4507 |
| XRN2 | -4339 |
| NOP14 | -4325 |
| MT-TF | -4317 |
| MT-CYB | -4300 |
| UTP3 | -4235 |
| NOL12 | -4204 |
| RPS3A | -4198 |
| MTERF4 | -4095 |
| DKC1 | -3900 |
| MT-ND5 | -3886 |
| FTSJ3 | -3824 |
| DHX37 | -3746 |
| NOL6 | -3745 |
| WDR18 | -3588 |
| RPL6 | -3572 |
| EXOSC6 | -3281 |
| SENP3 | -3240 |
| RPP25 | -3008 |
| MRM3 | -2993 |
| MT-RNR1 | -2749 |
| MRM2 | -2590 |
| NAT10 | -2471 |
| MRM1 | -2434 |
| PDCD11 | -2433 |
| MT-TL1 | -2174 |
| DCAF13 | -2140 |
| MT-CO1 | -1832 |
| MT-RNR2 | -1586 |
| BMS1 | -1386 |
| PELP1 | -1334 |
| RCL1 | -1049 |
| EBNA1BP2 | -612 |
| RPS26 | -480 |
| WDR43 | 173 |
| NOC4L | 242 |
| GAR1 | 247 |
| NOP56 | 255 |
| RPL22L1 | 543 |
| WDR3 | 587 |
| MPHOSPH6 | 1331 |
| RPS4Y1 | 1781 |
| RBM28 | 1934 |
| RRP1 | 2099 |
| RIOK1 | 2485 |
| RPP40 | 3512 |
| RPSA | 3639 |
| UTP4 | 3818 |
| UTP14A | 3830 |
| TSR1 | 4429 |
| GNL3 | 4468 |
| EXOSC3 | 4492 |
| NIP7 | 4725 |
| PRORP | 5007 |
| UTP18 | 5066 |
| EXOSC1 | 5377 |
| UTP14C | 5465 |
| HEATR1 | 5693 |
| LTV1 | 5755 |
| MTREX | 5937 |
| WDR36 | 6105 |
| MT-ND4 | 6120 |
| FCF1 | 6440 |
| ISG20L2 | 6650 |
| EXOSC10 | 6728 |
| RPP38 | 6731 |
| UTP11 | 6940 |
| WDR12 | 7357 |
| EXOSC8 | 7446 |
| TFB1M | 7599 |
| THUMPD1 | 8089 |
| RPP14 | 8112 |
| WDR75 | 8139 |
| RPP30 | 8378 |
| NSUN4 | 8390 |
| DDX47 | 8393 |
| KRR1 | 8516 |
| DDX21 | 8855 |
| NOP58 | 8946 |
| TRMT10C | 9005 |
| EMG1 | 9066 |
| NOL11 | 9308 |
| UTP6 | 9331 |
| DIMT1 | 9339 |
| NOL9 | 9592 |
| PNO1 | 9716 |
| RPS27L | 10040 |
| UTP20 | 10090 |
| RIOK2 | 10096 |
| RIOK3 | 10278 |
| RPL3L | 10975 |
| EXOSC9 | 11199 |
| SNORD3A | 11394 |
| ERI1 | 11678 |
| C1D | 11804 |
| TEX10 | 11974 |
| DIS3 | 11991 |
| UTP15 | 12107 |
| MPHOSPH10 | 12389 |
| DDX52 | 12810 |
rRNA processing in the nucleus and cytosol
| 1357 | |
|---|---|
| set | rRNA processing in the nucleus and cytosol |
| setSize | 190 |
| pANOVA | 4.77e-21 |
| s.dist | -0.396 |
| p.adjustANOVA | 1.97e-19 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| TSR3 | -9119 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| FBL | -9080 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| TSR3 | -9119 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| FBL | -9080 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| EXOSC7 | -8983 |
| RPS3 | -8980 |
| PES1 | -8968 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| WDR46 | -8946 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| TRMT112 | -8899 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| BOP1 | -8551 |
| RPS15 | -8520 |
| DDX49 | -8519 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| CSNK1D | -8192 |
| RRP9 | -8183 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| RPP21 | -7716 |
| NHP2 | -7601 |
| NOP10 | -7526 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| EXOSC5 | -7321 |
| RPL4 | -7296 |
| PWP2 | -7275 |
| RPL24 | -7262 |
| SNU13 | -7206 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| NOP2 | -6828 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| BYSL | -6551 |
| TBL3 | -6536 |
| EXOSC4 | -6453 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| RPL28 | -5853 |
| IMP4 | -5773 |
| RPL26L1 | -5693 |
| IMP3 | -5241 |
| NOB1 | -5240 |
| RRP36 | -5194 |
| RPL23A | -5130 |
| CSNK1E | -5049 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| EXOSC2 | -4827 |
| RPS24 | -4741 |
| RRP7A | -4721 |
| LAS1L | -4647 |
| RPL9 | -4555 |
| NCL | -4507 |
| XRN2 | -4339 |
| NOP14 | -4325 |
| UTP3 | -4235 |
| NOL12 | -4204 |
| RPS3A | -4198 |
| DKC1 | -3900 |
| FTSJ3 | -3824 |
| DHX37 | -3746 |
| NOL6 | -3745 |
| WDR18 | -3588 |
| RPL6 | -3572 |
| EXOSC6 | -3281 |
| SENP3 | -3240 |
| RPP25 | -3008 |
| NAT10 | -2471 |
| PDCD11 | -2433 |
| DCAF13 | -2140 |
| BMS1 | -1386 |
| PELP1 | -1334 |
| RCL1 | -1049 |
| EBNA1BP2 | -612 |
| RPS26 | -480 |
| WDR43 | 173 |
| NOC4L | 242 |
| GAR1 | 247 |
| NOP56 | 255 |
| RPL22L1 | 543 |
| WDR3 | 587 |
| MPHOSPH6 | 1331 |
| RPS4Y1 | 1781 |
| RBM28 | 1934 |
| RRP1 | 2099 |
| RIOK1 | 2485 |
| RPP40 | 3512 |
| RPSA | 3639 |
| UTP4 | 3818 |
| UTP14A | 3830 |
| TSR1 | 4429 |
| GNL3 | 4468 |
| EXOSC3 | 4492 |
| NIP7 | 4725 |
| UTP18 | 5066 |
| EXOSC1 | 5377 |
| UTP14C | 5465 |
| HEATR1 | 5693 |
| LTV1 | 5755 |
| MTREX | 5937 |
| WDR36 | 6105 |
| FCF1 | 6440 |
| ISG20L2 | 6650 |
| EXOSC10 | 6728 |
| RPP38 | 6731 |
| UTP11 | 6940 |
| WDR12 | 7357 |
| EXOSC8 | 7446 |
| THUMPD1 | 8089 |
| RPP14 | 8112 |
| WDR75 | 8139 |
| RPP30 | 8378 |
| DDX47 | 8393 |
| KRR1 | 8516 |
| DDX21 | 8855 |
| NOP58 | 8946 |
| EMG1 | 9066 |
| NOL11 | 9308 |
| UTP6 | 9331 |
| DIMT1 | 9339 |
| NOL9 | 9592 |
| PNO1 | 9716 |
| RPS27L | 10040 |
| UTP20 | 10090 |
| RIOK2 | 10096 |
| RIOK3 | 10278 |
| RPL3L | 10975 |
| EXOSC9 | 11199 |
| SNORD3A | 11394 |
| ERI1 | 11678 |
| C1D | 11804 |
| TEX10 | 11974 |
| DIS3 | 11991 |
| UTP15 | 12107 |
| MPHOSPH10 | 12389 |
| DDX52 | 12810 |
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
| 1004 | |
|---|---|
| set | Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) |
| setSize | 26 |
| pANOVA | 0.000486 |
| s.dist | 0.395 |
| p.adjustANOVA | 0.0039 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RMI2 | 12658 |
| RAD50 | 12523 |
| RBBP8 | 12316 |
| RAD51C | 12128 |
| BRCA2 | 12075 |
| RAD51B | 11969 |
| RMI1 | 11690 |
| DNA2 | 10793 |
| RAD51AP1 | 10386 |
| RAD51 | 9641 |
| BRIP1 | 9186 |
| NBN | 8918 |
| BRCA1 | 8258 |
| BARD1 | 7611 |
| WRN | 5884 |
| PALB2 | 5581 |
| RAD51D | 5048 |
| ATM | 4076 |
| BLM | 2502 |
| EXO1 | 2421 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RMI2 | 12658 |
| RAD50 | 12523 |
| RBBP8 | 12316 |
| RAD51C | 12128 |
| BRCA2 | 12075 |
| RAD51B | 11969 |
| RMI1 | 11690 |
| DNA2 | 10793 |
| RAD51AP1 | 10386 |
| RAD51 | 9641 |
| BRIP1 | 9186 |
| NBN | 8918 |
| BRCA1 | 8258 |
| BARD1 | 7611 |
| WRN | 5884 |
| PALB2 | 5581 |
| RAD51D | 5048 |
| ATM | 4076 |
| BLM | 2502 |
| EXO1 | 2421 |
| TOP3A | 311 |
| XRCC2 | -143 |
| RTEL1 | -1912 |
| MRE11 | -3747 |
| KAT5 | -4264 |
| XRCC3 | -6350 |
Chondroitin sulfate/dermatan sulfate metabolism
| 179 | |
|---|---|
| set | Chondroitin sulfate/dermatan sulfate metabolism |
| setSize | 39 |
| pANOVA | 2.01e-05 |
| s.dist | -0.394 |
| p.adjustANOVA | 0.000272 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| UST | -8933 |
| GPC4 | -8599 |
| XYLT1 | -8163 |
| CHPF2 | -7738 |
| B3GAT3 | -7628 |
| B3GALT6 | -7527 |
| CHST13 | -7372 |
| CHST11 | -7067 |
| HEXA | -6991 |
| SDC4 | -6556 |
| CHST7 | -6400 |
| CHST14 | -6168 |
| IDUA | -5903 |
| VCAN | -5852 |
| DSE | -5817 |
| XYLT2 | -5595 |
| GPC2 | -4351 |
| CSGALNACT1 | -3715 |
| HYAL3 | -3530 |
| DCN | -3528 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| UST | -8933 |
| GPC4 | -8599 |
| XYLT1 | -8163 |
| CHPF2 | -7738 |
| B3GAT3 | -7628 |
| B3GALT6 | -7527 |
| CHST13 | -7372 |
| CHST11 | -7067 |
| HEXA | -6991 |
| SDC4 | -6556 |
| CHST7 | -6400 |
| CHST14 | -6168 |
| IDUA | -5903 |
| VCAN | -5852 |
| DSE | -5817 |
| XYLT2 | -5595 |
| GPC2 | -4351 |
| CSGALNACT1 | -3715 |
| HYAL3 | -3530 |
| DCN | -3528 |
| HEXB | -3456 |
| GPC1 | -3166 |
| B4GALT7 | -2929 |
| IDS | -2509 |
| CHPF | -1256 |
| CHSY1 | -1023 |
| B3GAT2 | -960 |
| CHST15 | 191 |
| HSPG2 | 202 |
| SDC2 | 317 |
| SDC3 | 325 |
| CSPG4 | 627 |
| ARSB | 1964 |
| B3GAT1 | 2158 |
| DSEL | 2297 |
| CHST12 | 3956 |
| CSGALNACT2 | 9698 |
| HYAL1 | 9992 |
| AGRN | 10192 |
Major pathway of rRNA processing in the nucleolus and cytosol
| 627 | |
|---|---|
| set | Major pathway of rRNA processing in the nucleolus and cytosol |
| setSize | 180 |
| pANOVA | 7.14e-20 |
| s.dist | -0.394 |
| p.adjustANOVA | 2.78e-18 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| FBL | -9080 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS2 | -9277 |
| RPL37 | -9273 |
| RPLP2 | -9256 |
| RPS29 | -9213 |
| RPL38 | -9186 |
| RPS17 | -9182 |
| RPL8 | -9153 |
| RPL36 | -9115 |
| RPS21 | -9109 |
| RPS12 | -9106 |
| FAU | -9095 |
| RPLP1 | -9087 |
| RPL10 | -9083 |
| FBL | -9080 |
| RPS10 | -9077 |
| RPL27 | -9063 |
| RPL36AL | -9053 |
| RPL29 | -9041 |
| RPL3 | -9027 |
| RPL7A | -9005 |
| RPS11 | -8997 |
| EXOSC7 | -8983 |
| RPS3 | -8980 |
| PES1 | -8968 |
| RPS16 | -8957 |
| RPLP0 | -8954 |
| WDR46 | -8946 |
| RPS27 | -8945 |
| RPL31 | -8937 |
| RPL37A | -8935 |
| RPS27A | -8920 |
| RPL14 | -8902 |
| RPS14 | -8888 |
| RPL27A | -8822 |
| RPS28 | -8811 |
| RPL30 | -8753 |
| RPS19 | -8708 |
| RPL41 | -8704 |
| RPL18A | -8687 |
| RPS9 | -8681 |
| RPS15A | -8679 |
| RPL18 | -8654 |
| RPL39 | -8609 |
| RPS5 | -8589 |
| RPS23 | -8566 |
| BOP1 | -8551 |
| RPS15 | -8520 |
| DDX49 | -8519 |
| RPL15 | -8482 |
| UBA52 | -8454 |
| RPL19 | -8396 |
| RPL36A | -8341 |
| RPL7 | -8333 |
| RPL17 | -8325 |
| RPL26 | -8284 |
| RPL12 | -8270 |
| RPL35A | -8243 |
| RPL32 | -8237 |
| CSNK1D | -8192 |
| RRP9 | -8183 |
| RPL35 | -8136 |
| RPS6 | -8135 |
| RPS7 | -8117 |
| RPS13 | -8112 |
| RPS25 | -8006 |
| RPS18 | -7912 |
| RPL23 | -7725 |
| RPL22 | -7719 |
| RPP21 | -7716 |
| RPL21 | -7466 |
| RPL5 | -7391 |
| EXOSC5 | -7321 |
| RPL4 | -7296 |
| PWP2 | -7275 |
| RPL24 | -7262 |
| SNU13 | -7206 |
| RPL11 | -6953 |
| RPS8 | -6940 |
| RPL13 | -6588 |
| RPL34 | -6557 |
| BYSL | -6551 |
| TBL3 | -6536 |
| EXOSC4 | -6453 |
| RPL13A | -6425 |
| RPS20 | -6373 |
| RPL10A | -6364 |
| RPL28 | -5853 |
| IMP4 | -5773 |
| RPL26L1 | -5693 |
| IMP3 | -5241 |
| NOB1 | -5240 |
| RRP36 | -5194 |
| RPL23A | -5130 |
| CSNK1E | -5049 |
| RPL39L | -4904 |
| RPS4X | -4837 |
| EXOSC2 | -4827 |
| RPS24 | -4741 |
| RRP7A | -4721 |
| LAS1L | -4647 |
| RPL9 | -4555 |
| NCL | -4507 |
| XRN2 | -4339 |
| NOP14 | -4325 |
| UTP3 | -4235 |
| NOL12 | -4204 |
| RPS3A | -4198 |
| FTSJ3 | -3824 |
| DHX37 | -3746 |
| NOL6 | -3745 |
| WDR18 | -3588 |
| RPL6 | -3572 |
| EXOSC6 | -3281 |
| SENP3 | -3240 |
| RPP25 | -3008 |
| PDCD11 | -2433 |
| DCAF13 | -2140 |
| BMS1 | -1386 |
| PELP1 | -1334 |
| RCL1 | -1049 |
| EBNA1BP2 | -612 |
| RPS26 | -480 |
| WDR43 | 173 |
| NOC4L | 242 |
| NOP56 | 255 |
| RPL22L1 | 543 |
| WDR3 | 587 |
| MPHOSPH6 | 1331 |
| RPS4Y1 | 1781 |
| RBM28 | 1934 |
| RRP1 | 2099 |
| RIOK1 | 2485 |
| RPP40 | 3512 |
| RPSA | 3639 |
| UTP4 | 3818 |
| UTP14A | 3830 |
| TSR1 | 4429 |
| GNL3 | 4468 |
| EXOSC3 | 4492 |
| NIP7 | 4725 |
| UTP18 | 5066 |
| EXOSC1 | 5377 |
| UTP14C | 5465 |
| HEATR1 | 5693 |
| LTV1 | 5755 |
| MTREX | 5937 |
| WDR36 | 6105 |
| FCF1 | 6440 |
| ISG20L2 | 6650 |
| EXOSC10 | 6728 |
| RPP38 | 6731 |
| UTP11 | 6940 |
| WDR12 | 7357 |
| EXOSC8 | 7446 |
| RPP14 | 8112 |
| WDR75 | 8139 |
| RPP30 | 8378 |
| DDX47 | 8393 |
| KRR1 | 8516 |
| DDX21 | 8855 |
| NOP58 | 8946 |
| EMG1 | 9066 |
| NOL11 | 9308 |
| UTP6 | 9331 |
| NOL9 | 9592 |
| PNO1 | 9716 |
| RPS27L | 10040 |
| UTP20 | 10090 |
| RIOK2 | 10096 |
| RIOK3 | 10278 |
| RPL3L | 10975 |
| EXOSC9 | 11199 |
| SNORD3A | 11394 |
| ERI1 | 11678 |
| C1D | 11804 |
| TEX10 | 11974 |
| DIS3 | 11991 |
| UTP15 | 12107 |
| MPHOSPH10 | 12389 |
| DDX52 | 12810 |
Regulation of localization of FOXO transcription factors
| 988 | |
|---|---|
| set | Regulation of localization of FOXO transcription factors |
| setSize | 12 |
| pANOVA | 0.0193 |
| s.dist | -0.39 |
| p.adjustANOVA | 0.0575 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| AKT1 | -8457 |
| FOXO4 | -8425 |
| AKT2 | -8110 |
| FOXO3 | -6813 |
| YWHAG | -6470 |
| FOXO6 | -5750 |
| FOXO1 | -2811 |
| YWHAQ | -1360 |
| SFN | -681 |
| AKT3 | 2977 |
| YWHAZ | 6237 |
| YWHAB | 9139 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| AKT1 | -8457 |
| FOXO4 | -8425 |
| AKT2 | -8110 |
| FOXO3 | -6813 |
| YWHAG | -6470 |
| FOXO6 | -5750 |
| FOXO1 | -2811 |
| YWHAQ | -1360 |
| SFN | -681 |
| AKT3 | 2977 |
| YWHAZ | 6237 |
| YWHAB | 9139 |
Cleavage of the damaged purine
| 193 | |
|---|---|
| set | Cleavage of the damaged purine |
| setSize | 24 |
| pANOVA | 0.000956 |
| s.dist | -0.389 |
| p.adjustANOVA | 0.00643 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| H2AZ1 | -8858 |
| H2AJ | -8549 |
| H2BC12 | -8076 |
| MPG | -7996 |
| ACD | -7237 |
| TINF2 | -6145 |
| H2AZ2 | -6100 |
| H2BC5 | -5801 |
| H2BC9 | -5742 |
| H2BC11 | -5279 |
| TERF2IP | -4196 |
| H2BC21 | -3775 |
| H2AC6 | -3542 |
| MUTYH | -2696 |
| H2BC15 | -2448 |
| OGG1 | -1091 |
| NEIL3 | -986 |
| H2BC17 | -873 |
| H2BC4 | -582 |
| H2BU1 | 1259 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H2AZ1 | -8858 |
| H2AJ | -8549 |
| H2BC12 | -8076 |
| MPG | -7996 |
| ACD | -7237 |
| TINF2 | -6145 |
| H2AZ2 | -6100 |
| H2BC5 | -5801 |
| H2BC9 | -5742 |
| H2BC11 | -5279 |
| TERF2IP | -4196 |
| H2BC21 | -3775 |
| H2AC6 | -3542 |
| MUTYH | -2696 |
| H2BC15 | -2448 |
| OGG1 | -1091 |
| NEIL3 | -986 |
| H2BC17 | -873 |
| H2BC4 | -582 |
| H2BU1 | 1259 |
| TERF2 | 5295 |
| H2AC20 | 5713 |
| TERF1 | 6644 |
| POT1 | 10265 |
Depurination
| 277 | |
|---|---|
| set | Depurination |
| setSize | 24 |
| pANOVA | 0.000956 |
| s.dist | -0.389 |
| p.adjustANOVA | 0.00643 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| H2AZ1 | -8858 |
| H2AJ | -8549 |
| H2BC12 | -8076 |
| MPG | -7996 |
| ACD | -7237 |
| TINF2 | -6145 |
| H2AZ2 | -6100 |
| H2BC5 | -5801 |
| H2BC9 | -5742 |
| H2BC11 | -5279 |
| TERF2IP | -4196 |
| H2BC21 | -3775 |
| H2AC6 | -3542 |
| MUTYH | -2696 |
| H2BC15 | -2448 |
| OGG1 | -1091 |
| NEIL3 | -986 |
| H2BC17 | -873 |
| H2BC4 | -582 |
| H2BU1 | 1259 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H2AZ1 | -8858 |
| H2AJ | -8549 |
| H2BC12 | -8076 |
| MPG | -7996 |
| ACD | -7237 |
| TINF2 | -6145 |
| H2AZ2 | -6100 |
| H2BC5 | -5801 |
| H2BC9 | -5742 |
| H2BC11 | -5279 |
| TERF2IP | -4196 |
| H2BC21 | -3775 |
| H2AC6 | -3542 |
| MUTYH | -2696 |
| H2BC15 | -2448 |
| OGG1 | -1091 |
| NEIL3 | -986 |
| H2BC17 | -873 |
| H2BC4 | -582 |
| H2BU1 | 1259 |
| TERF2 | 5295 |
| H2AC20 | 5713 |
| TERF1 | 6644 |
| POT1 | 10265 |
Recognition and association of DNA glycosylase with site containing an affected purine
| 939 | |
|---|---|
| set | Recognition and association of DNA glycosylase with site containing an affected purine |
| setSize | 24 |
| pANOVA | 0.000956 |
| s.dist | -0.389 |
| p.adjustANOVA | 0.00643 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| H2AZ1 | -8858 |
| H2AJ | -8549 |
| H2BC12 | -8076 |
| MPG | -7996 |
| ACD | -7237 |
| TINF2 | -6145 |
| H2AZ2 | -6100 |
| H2BC5 | -5801 |
| H2BC9 | -5742 |
| H2BC11 | -5279 |
| TERF2IP | -4196 |
| H2BC21 | -3775 |
| H2AC6 | -3542 |
| MUTYH | -2696 |
| H2BC15 | -2448 |
| OGG1 | -1091 |
| NEIL3 | -986 |
| H2BC17 | -873 |
| H2BC4 | -582 |
| H2BU1 | 1259 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H2AZ1 | -8858 |
| H2AJ | -8549 |
| H2BC12 | -8076 |
| MPG | -7996 |
| ACD | -7237 |
| TINF2 | -6145 |
| H2AZ2 | -6100 |
| H2BC5 | -5801 |
| H2BC9 | -5742 |
| H2BC11 | -5279 |
| TERF2IP | -4196 |
| H2BC21 | -3775 |
| H2AC6 | -3542 |
| MUTYH | -2696 |
| H2BC15 | -2448 |
| OGG1 | -1091 |
| NEIL3 | -986 |
| H2BC17 | -873 |
| H2BC4 | -582 |
| H2BU1 | 1259 |
| TERF2 | 5295 |
| H2AC20 | 5713 |
| TERF1 | 6644 |
| POT1 | 10265 |
Here is the session info with all the versions of packages used.
sessionInfo()## R version 4.0.2 (2020-06-22)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 18.04.5 LTS
##
## Matrix products: default
## BLAS: /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.7.1
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.7.1
##
## locale:
## [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
## [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8
## [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
## [7] LC_PAPER=en_US.UTF-8 LC_NAME=C
## [9] LC_ADDRESS=C LC_TELEPHONE=C
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
##
## attached base packages:
## [1] parallel stats4 stats graphics grDevices utils datasets
## [8] methods base
##
## other attached packages:
## [1] pkgload_1.1.0 GGally_2.0.0
## [3] beeswarm_0.2.3 gtools_3.8.2
## [5] echarts4r_0.3.2 mitch_1.0.6
## [7] MASS_7.3-52 fgsea_1.14.0
## [9] gplots_3.0.3 DESeq2_1.28.1
## [11] SummarizedExperiment_1.18.1 DelayedArray_0.14.0
## [13] matrixStats_0.56.0 Biobase_2.48.0
## [15] GenomicRanges_1.40.0 GenomeInfoDb_1.24.2
## [17] IRanges_2.22.2 S4Vectors_0.26.1
## [19] BiocGenerics_0.34.0 reshape2_1.4.4
## [21] forcats_0.5.0 stringr_1.4.0
## [23] dplyr_1.0.0 purrr_0.3.4
## [25] readr_1.3.1 tidyr_1.1.0
## [27] tibble_3.0.1 ggplot2_3.3.2
## [29] tidyverse_1.3.0
##
## loaded via a namespace (and not attached):
## [1] colorspace_1.4-1 ellipsis_0.3.1 rprojroot_1.3-2
## [4] XVector_0.28.0 fs_1.4.2 rstudioapi_0.11
## [7] bit64_0.9-7 AnnotationDbi_1.50.1 fansi_0.4.1
## [10] lubridate_1.7.9 xml2_1.3.2 splines_4.0.2
## [13] geneplotter_1.66.0 knitr_1.29 jsonlite_1.7.0
## [16] broom_0.5.6 annotate_1.66.0 dbplyr_1.4.4
## [19] shiny_1.5.0 compiler_4.0.2 httr_1.4.1
## [22] backports_1.1.8 assertthat_0.2.1 Matrix_1.2-18
## [25] fastmap_1.0.1 cli_2.0.2 later_1.1.0.1
## [28] htmltools_0.5.0 tools_4.0.2 gtable_0.3.0
## [31] glue_1.4.1 GenomeInfoDbData_1.2.3 fastmatch_1.1-0
## [34] Rcpp_1.0.4.6 cellranger_1.1.0 vctrs_0.3.1
## [37] gdata_2.18.0 nlme_3.1-148 xfun_0.15
## [40] testthat_2.3.2 rvest_0.3.5 mime_0.9
## [43] lifecycle_0.2.0 XML_3.99-0.3 zlibbioc_1.34.0
## [46] scales_1.1.1 hms_0.5.3 promises_1.1.1
## [49] RColorBrewer_1.1-2 yaml_2.2.1 memoise_1.1.0
## [52] gridExtra_2.3 reshape_0.8.8 stringi_1.4.6
## [55] RSQLite_2.2.0 highr_0.8 genefilter_1.70.0
## [58] desc_1.2.0 caTools_1.18.0 BiocParallel_1.22.0
## [61] rlang_0.4.6 pkgconfig_2.0.3 bitops_1.0-6
## [64] evaluate_0.14 lattice_0.20-41 htmlwidgets_1.5.1
## [67] bit_1.1-15.2 tidyselect_1.1.0 plyr_1.8.6
## [70] magrittr_1.5 R6_2.4.1 generics_0.0.2
## [73] DBI_1.1.0 pillar_1.4.4 haven_2.3.1
## [76] withr_2.2.0 survival_3.2-3 RCurl_1.98-1.2
## [79] modelr_0.1.8 crayon_1.3.4 KernSmooth_2.23-17
## [82] rmarkdown_2.3 locfit_1.5-9.4 grid_4.0.2
## [85] readxl_1.3.1 data.table_1.12.8 blob_1.2.1
## [88] reprex_0.3.0 digest_0.6.25 pbmcapply_1.5.0
## [91] xtable_1.8-4 httpuv_1.5.4 munsell_0.5.0END of report