date generated: 2020-09-10

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

##                   x
## A1BG      2.6192564
## A1BG-AS1  0.5230655
## A1CF      0.5526173
## A2M      -3.3389616
## A2M-AS1  -3.1580711
## A2ML1    -0.3535245

Here are some metrics about the input data profile:

Profile metrics
Profile metrics
num_genesets 2400
num_genes_in_profile 21907
duplicated_genes_present 0
num_profile_genes_in_sets 8459
num_profile_genes_not_in_sets 13448

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt

Gene sets metrics
Gene sets metrics
num_genesets 2400
num_genesets_excluded 1036
num_genesets_included 1364

Differential pathway expression


Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 100 gene sets

set setSize pANOVA s.dist p.adjustANOVA
Neutrophil degranulation 458 0.00e+00 0.5860 2.00e-100
Innate Immune System 968 5.83e-84 0.3670 3.97e-81
Immune System 1894 3.07e-46 0.1980 1.40e-43
Membrane Trafficking 559 5.33e-36 0.3090 1.82e-33
Vesicle-mediated transport 650 1.64e-31 0.2680 4.48e-29
Signal Transduction 1894 7.04e-28 0.1520 1.60e-25
Hemostasis 550 5.25e-23 0.2460 1.02e-20
Metabolism 1772 1.78e-22 0.1390 3.04e-20
Platelet activation, signaling and aggregation 221 1.35e-20 0.3630 2.05e-18
Signaling by Receptor Tyrosine Kinases 414 1.68e-20 0.2660 2.29e-18
Signaling by Interleukins 386 1.71e-19 0.2680 2.12e-17
Metabolism of proteins 1719 1.86e-19 0.1310 2.12e-17
Post-translational protein modification 1194 5.60e-19 0.1530 5.87e-17
Response to elevated platelet cytosolic Ca2+ 110 1.25e-16 0.4570 1.22e-14
Platelet degranulation 106 5.81e-16 0.4550 5.29e-14
Toll-like Receptor Cascades 143 2.29e-15 0.3840 1.96e-13
Asparagine N-linked glycosylation 269 5.32e-15 0.2770 4.27e-13
Metabolism of lipids 625 9.17e-15 0.1810 6.95e-13
Disease 1303 1.32e-14 0.1270 9.50e-13
Transport of small molecules 561 1.57e-14 0.1900 1.07e-12
Toll Like Receptor 4 (TLR4) Cascade 121 3.21e-14 0.3990 2.08e-12
rRNA processing 219 2.40e-13 -0.2870 1.49e-11
ER to Golgi Anterograde Transport 129 2.87e-13 0.3720 1.53e-11
MyD88:MAL(TIRAP) cascade initiated on plasma membrane 92 3.03e-13 0.4400 1.53e-11
Toll Like Receptor 2 (TLR2) Cascade 92 3.03e-13 0.4400 1.53e-11
Toll Like Receptor TLR1:TLR2 Cascade 92 3.03e-13 0.4400 1.53e-11
Toll Like Receptor TLR6:TLR2 Cascade 92 3.03e-13 0.4400 1.53e-11
rRNA processing in the nucleus and cytosol 190 3.58e-13 -0.3060 1.75e-11
Signaling by NOTCH 183 3.84e-13 0.3110 1.81e-11
Interleukin-1 signaling 98 5.37e-13 0.4220 2.44e-11
Diseases of signal transduction by growth factor receptors and second messengers 343 9.13e-13 0.2240 4.02e-11
Major pathway of rRNA processing in the nucleolus and cytosol 180 1.68e-12 -0.3050 7.17e-11
Clathrin-mediated endocytosis 127 3.15e-12 0.3580 1.30e-10
Signaling by Rho GTPases 367 4.57e-12 0.2100 1.83e-10
Interleukin-1 family signaling 125 8.55e-12 0.3530 3.33e-10
Signaling by NTRKs 116 9.74e-12 0.3660 3.69e-10
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 88 1.49e-11 0.4160 5.49e-10
Transport to the Golgi and subsequent modification 155 1.60e-11 0.3130 5.73e-10
Antigen processing-Cross presentation 98 1.88e-11 0.3920 6.58e-10
RHO GTPase Effectors 250 2.78e-11 0.2440 9.48e-10
MyD88 dependent cascade initiated on endosome 89 4.41e-11 0.4040 1.43e-09
Toll Like Receptor 7/8 (TLR7/8) Cascade 89 4.41e-11 0.4040 1.43e-09
Toll Like Receptor 9 (TLR9) Cascade 93 7.92e-11 0.3900 2.51e-09
Signaling by NTRK1 (TRKA) 101 1.31e-10 0.3700 4.06e-09
Translocation of ZAP-70 to Immunological synapse 24 2.81e-10 -0.7440 8.52e-09
Gene expression (Transcription) 1335 4.00e-10 -0.1020 1.19e-08
RHO GTPases Activate WASPs and WAVEs 35 4.57e-10 0.6090 1.33e-08
Intra-Golgi and retrograde Golgi-to-ER traffic 179 5.04e-10 0.2690 1.42e-08
MyD88 cascade initiated on plasma membrane 82 5.31e-10 0.3970 1.42e-08
Toll Like Receptor 10 (TLR10) Cascade 82 5.31e-10 0.3970 1.42e-08
Toll Like Receptor 5 (TLR5) Cascade 82 5.31e-10 0.3970 1.42e-08
Developmental Biology 732 1.07e-09 0.1320 2.80e-08
Golgi-to-ER retrograde transport 111 1.79e-09 0.3300 4.60e-08
COPI-mediated anterograde transport 78 1.90e-09 0.3930 4.80e-08
Programmed Cell Death 171 2.10e-09 0.2650 5.16e-08
Autophagy 124 2.12e-09 0.3110 5.16e-08
Apoptosis 168 2.16e-09 0.2680 5.16e-08
EPH-Ephrin signaling 79 2.31e-09 0.3890 5.44e-08
Amyloid fiber formation 51 2.44e-09 0.4830 5.64e-08
Signaling by WNT 254 4.05e-09 0.2140 9.21e-08
RHO GTPases activate PKNs 48 6.95e-09 0.4830 1.56e-07
MyD88-independent TLR4 cascade 96 7.99e-09 0.3410 1.73e-07
TRIF(TICAM1)-mediated TLR4 signaling 96 7.99e-09 0.3410 1.73e-07
ROS and RNS production in phagocytes 31 8.23e-09 0.5980 1.75e-07
Generic Transcription Pathway 1085 1.09e-08 -0.1030 2.28e-07
Cellular responses to external stimuli 506 1.91e-08 0.1460 3.95e-07
COPI-independent Golgi-to-ER retrograde traffic 33 2.11e-08 0.5630 4.30e-07
ER-Phagosome pathway 83 2.17e-08 0.3550 4.35e-07
Class I MHC mediated antigen processing & presentation 350 2.99e-08 0.1720 5.91e-07
Cellular response to hypoxia 72 3.43e-08 0.3760 6.69e-07
Detoxification of Reactive Oxygen Species 32 3.64e-08 0.5620 6.98e-07
Cargo recognition for clathrin-mediated endocytosis 90 4.34e-08 0.3340 8.21e-07
Signaling by Nuclear Receptors 217 5.11e-08 0.2150 9.54e-07
COPII-mediated vesicle transport 65 5.29e-08 0.3900 9.67e-07
RUNX1 regulates transcription of genes involved in differentiation of HSCs 83 5.32e-08 0.3450 9.67e-07
Cellular responses to stress 500 5.60e-08 0.1420 9.93e-07
The citric acid (TCA) cycle and respiratory electron transport 172 5.61e-08 0.2400 9.93e-07
Infectious disease 724 7.34e-08 0.1170 1.28e-06
trans-Golgi Network Vesicle Budding 69 9.29e-08 0.3720 1.60e-06
ESR-mediated signaling 161 1.07e-07 0.2430 1.83e-06
PD-1 signaling 28 1.11e-07 -0.5790 1.87e-06
rRNA modification in the nucleus and cytosol 59 1.39e-07 -0.3960 2.32e-06
RAB GEFs exchange GTP for GDP on RABs 88 1.51e-07 0.3240 2.48e-06
Rab regulation of trafficking 121 1.59e-07 0.2760 2.59e-06
MAP2K and MAPK activation 34 1.81e-07 0.5170 2.91e-06
tRNA processing 136 2.88e-07 -0.2550 4.57e-06
Post-translational protein phosphorylation 70 2.94e-07 0.3540 4.61e-06
CLEC7A (Dectin-1) signaling 97 3.16e-07 0.3000 4.90e-06
DNA strand elongation 32 3.21e-07 -0.5220 4.91e-06
Signaling by BRAF and RAF fusions 57 3.30e-07 0.3910 4.98e-06
Intracellular signaling by second messengers 273 3.32e-07 0.1790 4.98e-06
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 124 3.67e-07 0.2640 5.45e-06
C-type lectin receptors (CLRs) 129 3.78e-07 0.2590 5.54e-06
RNA Polymerase II Transcription 1204 4.09e-07 -0.0867 5.94e-06
VEGFA-VEGFR2 Pathway 92 4.27e-07 0.3050 6.13e-06
MAP kinase activation 63 4.52e-07 0.3670 6.43e-06
PIP3 activates AKT signaling 241 6.02e-07 0.1870 8.46e-06
Toll Like Receptor 3 (TLR3) Cascade 92 6.70e-07 0.3000 9.33e-06
Signaling by NOTCH4 79 6.95e-07 0.3230 9.57e-06
Signaling by MET 61 7.13e-07 0.3670 9.72e-06


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pANOVA s.dist p.adjustANOVA
Neutrophil degranulation 458 0.00e+00 5.86e-01 2.00e-100
Innate Immune System 968 5.83e-84 3.67e-01 3.97e-81
Immune System 1894 3.07e-46 1.98e-01 1.40e-43
Membrane Trafficking 559 5.33e-36 3.09e-01 1.82e-33
Vesicle-mediated transport 650 1.64e-31 2.68e-01 4.48e-29
Signal Transduction 1894 7.04e-28 1.52e-01 1.60e-25
Hemostasis 550 5.25e-23 2.46e-01 1.02e-20
Metabolism 1772 1.78e-22 1.39e-01 3.04e-20
Platelet activation, signaling and aggregation 221 1.35e-20 3.63e-01 2.05e-18
Signaling by Receptor Tyrosine Kinases 414 1.68e-20 2.66e-01 2.29e-18
Signaling by Interleukins 386 1.71e-19 2.68e-01 2.12e-17
Metabolism of proteins 1719 1.86e-19 1.31e-01 2.12e-17
Post-translational protein modification 1194 5.60e-19 1.53e-01 5.87e-17
Response to elevated platelet cytosolic Ca2+ 110 1.25e-16 4.57e-01 1.22e-14
Platelet degranulation 106 5.81e-16 4.55e-01 5.29e-14
Toll-like Receptor Cascades 143 2.29e-15 3.84e-01 1.96e-13
Asparagine N-linked glycosylation 269 5.32e-15 2.77e-01 4.27e-13
Metabolism of lipids 625 9.17e-15 1.81e-01 6.95e-13
Disease 1303 1.32e-14 1.27e-01 9.50e-13
Transport of small molecules 561 1.57e-14 1.90e-01 1.07e-12
Toll Like Receptor 4 (TLR4) Cascade 121 3.21e-14 3.99e-01 2.08e-12
rRNA processing 219 2.40e-13 -2.87e-01 1.49e-11
ER to Golgi Anterograde Transport 129 2.87e-13 3.72e-01 1.53e-11
MyD88:MAL(TIRAP) cascade initiated on plasma membrane 92 3.03e-13 4.40e-01 1.53e-11
Toll Like Receptor 2 (TLR2) Cascade 92 3.03e-13 4.40e-01 1.53e-11
Toll Like Receptor TLR1:TLR2 Cascade 92 3.03e-13 4.40e-01 1.53e-11
Toll Like Receptor TLR6:TLR2 Cascade 92 3.03e-13 4.40e-01 1.53e-11
rRNA processing in the nucleus and cytosol 190 3.58e-13 -3.06e-01 1.75e-11
Signaling by NOTCH 183 3.84e-13 3.11e-01 1.81e-11
Interleukin-1 signaling 98 5.37e-13 4.22e-01 2.44e-11
Diseases of signal transduction by growth factor receptors and second messengers 343 9.13e-13 2.24e-01 4.02e-11
Major pathway of rRNA processing in the nucleolus and cytosol 180 1.68e-12 -3.05e-01 7.17e-11
Clathrin-mediated endocytosis 127 3.15e-12 3.58e-01 1.30e-10
Signaling by Rho GTPases 367 4.57e-12 2.10e-01 1.83e-10
Interleukin-1 family signaling 125 8.55e-12 3.53e-01 3.33e-10
Signaling by NTRKs 116 9.74e-12 3.66e-01 3.69e-10
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 88 1.49e-11 4.16e-01 5.49e-10
Transport to the Golgi and subsequent modification 155 1.60e-11 3.13e-01 5.73e-10
Antigen processing-Cross presentation 98 1.88e-11 3.92e-01 6.58e-10
RHO GTPase Effectors 250 2.78e-11 2.44e-01 9.48e-10
MyD88 dependent cascade initiated on endosome 89 4.41e-11 4.04e-01 1.43e-09
Toll Like Receptor 7/8 (TLR7/8) Cascade 89 4.41e-11 4.04e-01 1.43e-09
Toll Like Receptor 9 (TLR9) Cascade 93 7.92e-11 3.90e-01 2.51e-09
Signaling by NTRK1 (TRKA) 101 1.31e-10 3.70e-01 4.06e-09
Translocation of ZAP-70 to Immunological synapse 24 2.81e-10 -7.44e-01 8.52e-09
Gene expression (Transcription) 1335 4.00e-10 -1.02e-01 1.19e-08
RHO GTPases Activate WASPs and WAVEs 35 4.57e-10 6.09e-01 1.33e-08
Intra-Golgi and retrograde Golgi-to-ER traffic 179 5.04e-10 2.69e-01 1.42e-08
MyD88 cascade initiated on plasma membrane 82 5.31e-10 3.97e-01 1.42e-08
Toll Like Receptor 10 (TLR10) Cascade 82 5.31e-10 3.97e-01 1.42e-08
Toll Like Receptor 5 (TLR5) Cascade 82 5.31e-10 3.97e-01 1.42e-08
Developmental Biology 732 1.07e-09 1.32e-01 2.80e-08
Golgi-to-ER retrograde transport 111 1.79e-09 3.30e-01 4.60e-08
COPI-mediated anterograde transport 78 1.90e-09 3.93e-01 4.80e-08
Programmed Cell Death 171 2.10e-09 2.65e-01 5.16e-08
Autophagy 124 2.12e-09 3.11e-01 5.16e-08
Apoptosis 168 2.16e-09 2.68e-01 5.16e-08
EPH-Ephrin signaling 79 2.31e-09 3.89e-01 5.44e-08
Amyloid fiber formation 51 2.44e-09 4.83e-01 5.64e-08
Signaling by WNT 254 4.05e-09 2.14e-01 9.21e-08
RHO GTPases activate PKNs 48 6.95e-09 4.83e-01 1.56e-07
MyD88-independent TLR4 cascade 96 7.99e-09 3.41e-01 1.73e-07
TRIF(TICAM1)-mediated TLR4 signaling 96 7.99e-09 3.41e-01 1.73e-07
ROS and RNS production in phagocytes 31 8.23e-09 5.98e-01 1.75e-07
Generic Transcription Pathway 1085 1.09e-08 -1.03e-01 2.28e-07
Cellular responses to external stimuli 506 1.91e-08 1.46e-01 3.95e-07
COPI-independent Golgi-to-ER retrograde traffic 33 2.11e-08 5.63e-01 4.30e-07
ER-Phagosome pathway 83 2.17e-08 3.55e-01 4.35e-07
Class I MHC mediated antigen processing & presentation 350 2.99e-08 1.72e-01 5.91e-07
Cellular response to hypoxia 72 3.43e-08 3.76e-01 6.69e-07
Detoxification of Reactive Oxygen Species 32 3.64e-08 5.62e-01 6.98e-07
Cargo recognition for clathrin-mediated endocytosis 90 4.34e-08 3.34e-01 8.21e-07
Signaling by Nuclear Receptors 217 5.11e-08 2.15e-01 9.54e-07
COPII-mediated vesicle transport 65 5.29e-08 3.90e-01 9.67e-07
RUNX1 regulates transcription of genes involved in differentiation of HSCs 83 5.32e-08 3.45e-01 9.67e-07
Cellular responses to stress 500 5.60e-08 1.42e-01 9.93e-07
The citric acid (TCA) cycle and respiratory electron transport 172 5.61e-08 2.40e-01 9.93e-07
Infectious disease 724 7.34e-08 1.17e-01 1.28e-06
trans-Golgi Network Vesicle Budding 69 9.29e-08 3.72e-01 1.60e-06
ESR-mediated signaling 161 1.07e-07 2.43e-01 1.83e-06
PD-1 signaling 28 1.11e-07 -5.79e-01 1.87e-06
rRNA modification in the nucleus and cytosol 59 1.39e-07 -3.96e-01 2.32e-06
RAB GEFs exchange GTP for GDP on RABs 88 1.51e-07 3.24e-01 2.48e-06
Rab regulation of trafficking 121 1.59e-07 2.76e-01 2.59e-06
MAP2K and MAPK activation 34 1.81e-07 5.17e-01 2.91e-06
tRNA processing 136 2.88e-07 -2.55e-01 4.57e-06
Post-translational protein phosphorylation 70 2.94e-07 3.54e-01 4.61e-06
CLEC7A (Dectin-1) signaling 97 3.16e-07 3.00e-01 4.90e-06
DNA strand elongation 32 3.21e-07 -5.22e-01 4.91e-06
Signaling by BRAF and RAF fusions 57 3.30e-07 3.91e-01 4.98e-06
Intracellular signaling by second messengers 273 3.32e-07 1.79e-01 4.98e-06
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 124 3.67e-07 2.64e-01 5.45e-06
C-type lectin receptors (CLRs) 129 3.78e-07 2.59e-01 5.54e-06
RNA Polymerase II Transcription 1204 4.09e-07 -8.67e-02 5.94e-06
VEGFA-VEGFR2 Pathway 92 4.27e-07 3.05e-01 6.13e-06
MAP kinase activation 63 4.52e-07 3.67e-01 6.43e-06
PIP3 activates AKT signaling 241 6.02e-07 1.87e-01 8.46e-06
Toll Like Receptor 3 (TLR3) Cascade 92 6.70e-07 3.00e-01 9.33e-06
Signaling by NOTCH4 79 6.95e-07 3.23e-01 9.57e-06
Signaling by MET 61 7.13e-07 3.67e-01 9.72e-06
Generation of second messenger molecules 38 7.20e-07 -4.64e-01 9.72e-06
Cargo concentration in the ER 30 7.76e-07 5.21e-01 1.03e-05
Oncogenic MAPK signaling 73 7.76e-07 3.34e-01 1.03e-05
Macroautophagy 110 7.88e-07 2.72e-01 1.03e-05
EPHB-mediated forward signaling 32 7.98e-07 5.04e-01 1.03e-05
Cytokine Signaling in Immune system 736 8.01e-07 1.07e-01 1.03e-05
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 65 8.07e-07 3.54e-01 1.03e-05
IRAK4 deficiency (TLR2/4) 10 8.37e-07 8.99e-01 1.05e-05
MyD88 deficiency (TLR2/4) 10 8.37e-07 8.99e-01 1.05e-05
Transcriptional regulation of granulopoiesis 46 8.63e-07 4.19e-01 1.07e-05
Selenocysteine synthesis 92 8.72e-07 -2.97e-01 1.07e-05
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 80 9.74e-07 3.17e-01 1.19e-05
Pre-NOTCH Expression and Processing 65 1.18e-06 3.48e-01 1.43e-05
Endosomal Sorting Complex Required For Transport (ESCRT) 29 1.25e-06 5.20e-01 1.49e-05
L1CAM interactions 85 1.26e-06 3.04e-01 1.49e-05
Phosphorylation of CD3 and TCR zeta chains 27 1.38e-06 -5.37e-01 1.62e-05
Interleukin-17 signaling 68 1.45e-06 3.38e-01 1.68e-05
RAB geranylgeranylation 61 1.46e-06 3.57e-01 1.68e-05
Signaling by high-kinase activity BRAF mutants 31 1.54e-06 4.99e-01 1.77e-05
PPARA activates gene expression 104 1.84e-06 2.71e-01 2.09e-05
PCP/CE pathway 87 1.87e-06 2.96e-01 2.09e-05
Smooth Muscle Contraction 31 1.87e-06 4.95e-01 2.09e-05
Signaling by RAF1 mutants 34 1.94e-06 4.72e-01 2.16e-05
Extracellular matrix organization 219 2.25e-06 1.85e-01 2.47e-05
Golgi Associated Vesicle Biogenesis 55 2.33e-06 3.68e-01 2.55e-05
Activation of the pre-replicative complex 32 2.43e-06 -4.81e-01 2.62e-05
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism 12 2.46e-06 7.85e-01 2.62e-05
alpha-linolenic acid (ALA) metabolism 12 2.46e-06 7.85e-01 2.62e-05
Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 54 2.48e-06 3.70e-01 2.63e-05
Defective CFTR causes cystic fibrosis 60 2.57e-06 3.51e-01 2.70e-05
Iron uptake and transport 52 2.62e-06 3.77e-01 2.71e-05
MAPK family signaling cascades 270 2.63e-06 1.66e-01 2.71e-05
Protein ubiquitination 72 3.07e-06 3.18e-01 3.14e-05
TCF dependent signaling in response to WNT 166 3.21e-06 2.09e-01 3.27e-05
Signaling by VEGF 100 3.27e-06 2.69e-01 3.27e-05
Regulation of PTEN stability and activity 67 3.28e-06 3.29e-01 3.27e-05
RNA Polymerase I Promoter Opening 19 3.29e-06 6.16e-01 3.27e-05
Budding and maturation of HIV virion 26 3.45e-06 5.26e-01 3.41e-05
Respiratory electron transport 101 3.58e-06 2.67e-01 3.52e-05
Interleukin-4 and Interleukin-13 signaling 92 3.68e-06 2.79e-01 3.58e-05
Deubiquitination 242 3.70e-06 1.73e-01 3.58e-05
Integration of energy metabolism 86 3.84e-06 2.88e-01 3.64e-05
Paradoxical activation of RAF signaling by kinase inactive BRAF 38 3.90e-06 4.33e-01 3.64e-05
Signaling by RAS mutants 38 3.90e-06 4.33e-01 3.64e-05
Signaling by moderate kinase activity BRAF mutants 38 3.90e-06 4.33e-01 3.64e-05
Signaling downstream of RAS mutants 38 3.90e-06 4.33e-01 3.64e-05
Regulation of mRNA stability by proteins that bind AU-rich elements 88 3.93e-06 2.85e-01 3.64e-05
Beta-catenin independent WNT signaling 137 4.52e-06 2.27e-01 4.16e-05
Antimicrobial peptides 33 4.93e-06 4.59e-01 4.51e-05
Regulation of lipid metabolism by PPARalpha 106 5.54e-06 2.55e-01 5.04e-05
Cross-presentation of soluble exogenous antigens (endosomes) 48 5.62e-06 3.79e-01 5.07e-05
Hedgehog ligand biogenesis 59 5.69e-06 3.41e-01 5.10e-05
Peptide chain elongation 88 5.95e-06 -2.79e-01 5.31e-05
Insulin receptor recycling 21 6.43e-06 5.69e-01 5.69e-05
Eukaryotic Translation Elongation 93 6.47e-06 -2.71e-01 5.69e-05
Regulation of ornithine decarboxylase (ODC) 50 6.72e-06 3.68e-01 5.88e-05
Hh mutants abrogate ligand secretion 55 6.85e-06 3.51e-01 5.95e-05
Transferrin endocytosis and recycling 26 6.92e-06 5.09e-01 5.97e-05
Negative regulation of NOTCH4 signaling 54 7.02e-06 3.53e-01 6.02e-05
Influenza Viral RNA Transcription and Replication 135 7.53e-06 -2.23e-01 6.42e-05
ABC transporter disorders 71 7.90e-06 3.07e-01 6.69e-05
MAPK1/MAPK3 signaling 236 8.18e-06 1.69e-01 6.89e-05
Activation of ATR in response to replication stress 37 8.43e-06 -4.23e-01 7.05e-05
AUF1 (hnRNP D0) binds and destabilizes mRNA 54 8.71e-06 3.50e-01 7.22e-05
Diseases associated with the TLR signaling cascade 23 8.79e-06 5.35e-01 7.22e-05
Diseases of Immune System 23 8.79e-06 5.35e-01 7.22e-05
Hyaluronan uptake and degradation 12 8.85e-06 7.41e-01 7.23e-05
RHO GTPases Activate NADPH Oxidases 21 9.01e-06 5.60e-01 7.32e-05
Degradation of DVL 55 1.03e-05 3.44e-01 8.33e-05
Metabolism of carbohydrates 244 1.10e-05 1.63e-01 8.83e-05
Phospholipid metabolism 185 1.23e-05 1.86e-01 9.84e-05
Platelet Aggregation (Plug Formation) 28 1.27e-05 4.77e-01 1.00e-04
FLT3 Signaling 245 1.28e-05 1.62e-01 1.00e-04
Degradation of GLI2 by the proteasome 57 1.28e-05 3.34e-01 1.00e-04
Axon guidance 457 1.28e-05 1.19e-01 1.00e-04
PTEN Regulation 139 1.30e-05 2.14e-01 1.01e-04
Eukaryotic Translation Termination 92 1.32e-05 -2.63e-01 1.02e-04
Regulation of activated PAK-2p34 by proteasome mediated degradation 49 1.37e-05 3.59e-01 1.05e-04
Degradation of GLI1 by the proteasome 58 1.42e-05 3.29e-01 1.08e-04
Opioid Signalling 75 1.55e-05 2.89e-01 1.17e-04
Vif-mediated degradation of APOBEC3G 53 1.73e-05 3.41e-01 1.31e-04
Regulation of TLR by endogenous ligand 11 1.93e-05 7.44e-01 1.45e-04
Pre-NOTCH Transcription and Translation 49 1.95e-05 3.53e-01 1.46e-04
NIK-->noncanonical NF-kB signaling 58 1.99e-05 3.24e-01 1.47e-04
HDACs deacetylate histones 47 2.04e-05 3.59e-01 1.51e-04
Regulation of Apoptosis 52 2.18e-05 3.40e-01 1.60e-04
Nervous system development 476 2.40e-05 1.13e-01 1.75e-04
Dectin-1 mediated noncanonical NF-kB signaling 59 2.42e-05 3.18e-01 1.75e-04
Viral mRNA Translation 88 2.47e-05 -2.60e-01 1.78e-04
Senescence-Associated Secretory Phenotype (SASP) 66 2.52e-05 3.00e-01 1.81e-04
The role of GTSE1 in G2/M progression after G2 checkpoint 59 2.58e-05 3.17e-01 1.84e-04
HSP90 chaperone cycle for steroid hormone receptors (SHR) 36 2.62e-05 4.05e-01 1.85e-04
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 53 2.62e-05 3.34e-01 1.85e-04
GLI3 is processed to GLI3R by the proteasome 58 2.78e-05 3.18e-01 1.96e-04
Glycerophospholipid biosynthesis 106 2.89e-05 2.35e-01 2.02e-04
Selenoamino acid metabolism 114 2.96e-05 -2.26e-01 2.06e-04
MAPK6/MAPK4 signaling 83 3.05e-05 2.65e-01 2.11e-04
RAF/MAP kinase cascade 231 3.18e-05 1.59e-01 2.19e-04
Oxidative Stress Induced Senescence 79 3.24e-05 2.70e-01 2.22e-04
EGFR downregulation 27 3.34e-05 4.61e-01 2.28e-04
Metabolism of polyamines 58 3.35e-05 3.15e-01 2.28e-04
Activation of NF-kappaB in B cells 66 3.57e-05 2.94e-01 2.41e-04
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 21 4.10e-05 5.17e-01 2.74e-04
Neurodegenerative Diseases 21 4.10e-05 5.17e-01 2.74e-04
Neddylation 219 4.38e-05 1.60e-01 2.91e-04
Translocation of SLC2A4 (GLUT4) to the plasma membrane 48 4.45e-05 3.41e-01 2.95e-04
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 94 4.84e-05 -2.42e-01 3.19e-04
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51 4.97e-05 3.28e-01 3.23e-04
p53-Independent DNA Damage Response 51 4.97e-05 3.28e-01 3.23e-04
p53-Independent G1/S DNA damage checkpoint 51 4.97e-05 3.28e-01 3.23e-04
Leishmania infection 245 5.06e-05 1.50e-01 3.27e-04
Nuclear Events (kinase and transcription factor activation) 53 5.25e-05 3.21e-01 3.38e-04
Signal amplification 28 5.41e-05 4.41e-01 3.46e-04
E3 ubiquitin ligases ubiquitinate target proteins 52 5.50e-05 3.23e-01 3.51e-04
Ub-specific processing proteases 171 5.65e-05 1.78e-01 3.58e-04
Late endosomal microautophagy 30 6.00e-05 4.23e-01 3.79e-04
Vpu mediated degradation of CD4 51 6.08e-05 3.25e-01 3.82e-04
DNA methylation 20 6.16e-05 5.17e-01 3.85e-04
Degradation of beta-catenin by the destruction complex 84 6.67e-05 2.52e-01 4.15e-04
Cellular Senescence 144 6.80e-05 1.92e-01 4.22e-04
RHO GTPases Activate ROCKs 18 6.85e-05 5.42e-01 4.23e-04
Infection with Mycobacterium tuberculosis 26 7.20e-05 4.50e-01 4.42e-04
Lysosome Vesicle Biogenesis 32 7.32e-05 4.05e-01 4.48e-04
SARS-CoV Infections 83 7.53e-05 2.51e-01 4.58e-04
Homologous DNA Pairing and Strand Exchange 42 7.63e-05 -3.53e-01 4.62e-04
Metabolism of RNA 688 7.82e-05 -8.83e-02 4.72e-04
Regulation of RUNX3 expression and activity 55 8.07e-05 3.07e-01 4.85e-04
Signaling by EGFR 46 8.37e-05 3.35e-01 4.99e-04
Signaling by Insulin receptor 59 8.38e-05 2.96e-01 4.99e-04
Signalling to ERKs 32 8.47e-05 4.01e-01 5.02e-04
Platelet homeostasis 70 8.63e-05 2.71e-01 5.09e-04
Erythrocytes take up carbon dioxide and release oxygen 11 9.46e-05 6.80e-01 5.53e-04
O2/CO2 exchange in erythrocytes 11 9.46e-05 6.80e-01 5.53e-04
Advanced glycosylation endproduct receptor signaling 12 9.48e-05 6.51e-01 5.53e-04
Telomere C-strand (Lagging Strand) Synthesis 34 9.64e-05 -3.86e-01 5.59e-04
Ubiquitin-dependent degradation of Cyclin D 51 1.02e-04 3.15e-01 5.87e-04
Hedgehog 'on' state 76 1.08e-04 2.57e-01 6.23e-04
Negative regulation of MET activity 18 1.11e-04 5.26e-01 6.38e-04
Uptake and function of anthrax toxins 10 1.14e-04 7.05e-01 6.51e-04
tRNA processing in the nucleus 59 1.15e-04 -2.90e-01 6.51e-04
Amino acids regulate mTORC1 50 1.16e-04 3.15e-01 6.56e-04
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 11 1.17e-04 6.71e-01 6.57e-04
Ion channel transport 135 1.22e-04 1.92e-01 6.83e-04
Influenza Infection 154 1.22e-04 -1.79e-01 6.83e-04
Extension of Telomeres 51 1.26e-04 -3.10e-01 6.99e-04
Platelet sensitization by LDL 16 1.28e-04 5.53e-01 7.07e-04
Autodegradation of Cdh1 by Cdh1:APC/C 64 1.28e-04 2.77e-01 7.07e-04
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 22 1.29e-04 4.72e-01 7.07e-04
Unwinding of DNA 12 1.32e-04 -6.37e-01 7.21e-04
p130Cas linkage to MAPK signaling for integrins 11 1.32e-04 6.65e-01 7.21e-04
Estrogen-dependent gene expression 99 1.33e-04 2.22e-01 7.21e-04
Transcriptional regulation of white adipocyte differentiation 77 1.36e-04 2.51e-01 7.35e-04
Signaling by NOTCH1 67 1.37e-04 2.69e-01 7.35e-04
Diseases of programmed cell death 23 1.37e-04 4.59e-01 7.35e-04
Response of EIF2AK4 (GCN2) to amino acid deficiency 100 1.46e-04 -2.20e-01 7.80e-04
MTOR signalling 38 1.50e-04 3.55e-01 7.98e-04
Resolution of AP sites via the multiple-nucleotide patch replacement pathway 24 1.57e-04 -4.46e-01 8.36e-04
ABC-family proteins mediated transport 94 1.66e-04 2.25e-01 8.76e-04
Recycling pathway of L1 26 1.68e-04 4.26e-01 8.84e-04
RHO GTPases activate PAKs 20 1.70e-04 4.86e-01 8.94e-04
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 73 1.73e-04 2.54e-01 9.06e-04
Notch-HLH transcription pathway 28 1.86e-04 4.08e-01 9.66e-04
Sealing of the nuclear envelope (NE) by ESCRT-III 25 1.86e-04 4.32e-01 9.67e-04
Response of Mtb to phagocytosis 22 1.91e-04 4.59e-01 9.85e-04
Integrin signaling 22 2.08e-04 4.57e-01 1.07e-03
Synthesis of active ubiquitin: roles of E1 and E2 enzymes 30 2.11e-04 3.91e-01 1.08e-03
Hyaluronan metabolism 15 2.20e-04 5.51e-01 1.13e-03
Interferon alpha/beta signaling 57 2.25e-04 -2.82e-01 1.14e-03
Fanconi Anemia Pathway 36 2.43e-04 -3.53e-01 1.23e-03
Resolution of Abasic Sites (AP sites) 37 2.48e-04 -3.48e-01 1.25e-03
Autodegradation of the E3 ubiquitin ligase COP1 50 2.53e-04 2.99e-01 1.27e-03
APC/C:Cdc20 mediated degradation of Securin 67 2.63e-04 2.58e-01 1.32e-03
SCF-beta-TrCP mediated degradation of Emi1 54 2.64e-04 2.87e-01 1.32e-03
Chaperonin-mediated protein folding 84 2.68e-04 2.30e-01 1.33e-03
UCH proteinases 87 2.83e-04 2.25e-01 1.40e-03
Downstream signaling events of B Cell Receptor (BCR) 80 2.96e-04 2.34e-01 1.46e-03
Collagen degradation 28 3.05e-04 3.94e-01 1.50e-03
MHC class II antigen presentation 101 3.09e-04 2.08e-01 1.52e-03
RAF activation 32 3.35e-04 3.66e-01 1.64e-03
Metabolism of steroids 120 3.42e-04 1.89e-01 1.67e-03
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 51 3.51e-04 2.89e-01 1.71e-03
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 114 3.56e-04 -1.94e-01 1.72e-03
Nonsense-Mediated Decay (NMD) 114 3.56e-04 -1.94e-01 1.72e-03
Golgi Cisternae Pericentriolar Stack Reorganization 14 3.65e-04 5.50e-01 1.76e-03
TP53 Regulates Metabolic Genes 85 3.76e-04 2.23e-01 1.80e-03
Formation of a pool of free 40S subunits 100 3.77e-04 -2.06e-01 1.80e-03
Interferon Signaling 177 3.85e-04 -1.55e-01 1.83e-03
Presynaptic phase of homologous DNA pairing and strand exchange 39 4.00e-04 -3.28e-01 1.89e-03
Sphingolipid metabolism 77 4.07e-04 2.33e-01 1.92e-03
Inhibition of DNA recombination at telomere 35 4.21e-04 3.44e-01 1.98e-03
COPI-dependent Golgi-to-ER retrograde traffic 78 4.28e-04 2.31e-01 2.01e-03
G-protein beta:gamma signalling 29 4.44e-04 3.77e-01 2.07e-03
Transcriptional regulation by RUNX1 185 4.54e-04 1.49e-01 2.11e-03
Lagging Strand Synthesis 20 4.63e-04 -4.52e-01 2.15e-03
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 76 4.70e-04 2.32e-01 2.17e-03
Degradation of AXIN 54 4.87e-04 2.74e-01 2.25e-03
GRB2:SOS provides linkage to MAPK signaling for Integrins 12 4.97e-04 5.80e-01 2.28e-03
Energy dependent regulation of mTOR by LKB1-AMPK 27 5.03e-04 3.87e-01 2.30e-03
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 13 5.15e-04 5.56e-01 2.35e-03
Packaging Of Telomere Ends 20 5.17e-04 4.48e-01 2.35e-03
Stabilization of p53 55 5.37e-04 2.70e-01 2.43e-03
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 73 5.49e-04 2.34e-01 2.48e-03
Cdc20:Phospho-APC/C mediated degradation of Cyclin A 72 5.71e-04 2.35e-01 2.57e-03
activated TAK1 mediates p38 MAPK activation 19 5.78e-04 4.56e-01 2.59e-03
APC/C:Cdc20 mediated degradation of mitotic proteins 75 5.83e-04 2.30e-01 2.60e-03
CDK-mediated phosphorylation and removal of Cdc6 72 5.83e-04 2.34e-01 2.60e-03
Interactions of Rev with host cellular proteins 37 5.97e-04 -3.26e-01 2.65e-03
Rev-mediated nuclear export of HIV RNA 35 6.35e-04 -3.34e-01 2.81e-03
Degradation of the extracellular matrix 78 6.48e-04 2.23e-01 2.86e-03
Protein folding 90 6.57e-04 2.08e-01 2.89e-03
Regulation of RAS by GAPs 67 6.68e-04 2.40e-01 2.92e-03
Dissolution of Fibrin Clot 12 6.70e-04 5.67e-01 2.92e-03
Regulation of insulin secretion 60 6.70e-04 2.54e-01 2.92e-03
Retrograde neurotrophin signalling 12 6.74e-04 5.67e-01 2.93e-03
Signal transduction by L1 20 6.81e-04 4.39e-01 2.95e-03
MAPK targets/ Nuclear events mediated by MAP kinases 31 7.33e-04 3.50e-01 3.17e-03
Transmission across Chemical Synapses 172 7.60e-04 1.49e-01 3.26e-03
TBC/RABGAPs 45 7.61e-04 2.90e-01 3.26e-03
Adaptive Immune System 757 7.74e-04 7.18e-02 3.31e-03
Plasma lipoprotein assembly, remodeling, and clearance 53 8.47e-04 2.65e-01 3.59e-03
PCNA-Dependent Long Patch Base Excision Repair 21 8.48e-04 -4.21e-01 3.59e-03
NS1 Mediated Effects on Host Pathways 40 8.53e-04 -3.05e-01 3.59e-03
Signaling by Non-Receptor Tyrosine Kinases 48 8.53e-04 2.78e-01 3.59e-03
Signaling by PTK6 48 8.53e-04 2.78e-01 3.59e-03
Asymmetric localization of PCP proteins 61 8.66e-04 2.47e-01 3.64e-03
Costimulation by the CD28 family 74 8.86e-04 -2.23e-01 3.71e-03
Factors involved in megakaryocyte development and platelet production 117 8.93e-04 1.78e-01 3.72e-03
ERK/MAPK targets 22 8.93e-04 4.09e-01 3.72e-03
p75 NTR receptor-mediated signalling 89 9.07e-04 2.03e-01 3.76e-03
XBP1(S) activates chaperone genes 47 9.11e-04 2.80e-01 3.77e-03
HIV Infection 225 9.21e-04 1.28e-01 3.79e-03
Semaphorin interactions 57 9.23e-04 2.54e-01 3.79e-03
Extra-nuclear estrogen signaling 66 9.28e-04 2.36e-01 3.80e-03
SCF(Skp2)-mediated degradation of p27/p21 60 9.73e-04 2.46e-01 3.98e-03
Spry regulation of FGF signaling 16 9.96e-04 4.75e-01 4.06e-03
Transcriptional regulation by RUNX3 90 1.01e-03 2.01e-01 4.08e-03
Antigen processing: Ubiquitination & Proteasome degradation 289 1.01e-03 1.12e-01 4.11e-03
Neurotransmitter receptors and postsynaptic signal transmission 124 1.06e-03 1.70e-01 4.26e-03
DARPP-32 events 22 1.08e-03 4.02e-01 4.35e-03
Growth hormone receptor signaling 20 1.10e-03 4.21e-01 4.42e-03
Signaling by Hedgehog 121 1.10e-03 1.72e-01 4.42e-03
IRE1alpha activates chaperones 49 1.13e-03 2.69e-01 4.49e-03
Transcriptional regulation by RUNX2 103 1.14e-03 1.86e-01 4.52e-03
HDR through Homologous Recombination (HRR) 66 1.15e-03 -2.31e-01 4.56e-03
Gap junction trafficking 14 1.16e-03 5.01e-01 4.59e-03
Fatty acid metabolism 153 1.16e-03 1.52e-01 4.59e-03
CDT1 association with the CDC6:ORC:origin complex 58 1.18e-03 2.46e-01 4.65e-03
Neuronal System 259 1.19e-03 1.17e-01 4.67e-03
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function 53 1.21e-03 2.57e-01 4.72e-03
Complex I biogenesis 55 1.21e-03 2.52e-01 4.72e-03
Calnexin/calreticulin cycle 26 1.22e-03 3.66e-01 4.75e-03
N-glycan trimming in the ER and Calnexin/Calreticulin cycle 35 1.23e-03 3.16e-01 4.77e-03
ADP signalling through P2Y purinoceptor 1 21 1.25e-03 4.07e-01 4.82e-03
Metabolism of non-coding RNA 53 1.35e-03 -2.54e-01 5.19e-03
snRNP Assembly 53 1.35e-03 -2.54e-01 5.19e-03
Signaling by Erythropoietin 24 1.35e-03 3.78e-01 5.19e-03
Thrombin signalling through proteinase activated receptors (PARs) 27 1.42e-03 3.55e-01 5.42e-03
NOTCH1 Intracellular Domain Regulates Transcription 45 1.45e-03 2.74e-01 5.53e-03
GPVI-mediated activation cascade 31 1.48e-03 3.30e-01 5.64e-03
Regulation of cholesterol biosynthesis by SREBP (SREBF) 55 1.56e-03 2.47e-01 5.90e-03
Rho GTPase cycle 126 1.57e-03 1.63e-01 5.92e-03
GAB1 signalosome 15 1.59e-03 4.71e-01 5.97e-03
InlB-mediated entry of Listeria monocytogenes into host cell 12 1.61e-03 5.26e-01 6.06e-03
NEP/NS2 Interacts with the Cellular Export Machinery 32 1.67e-03 -3.21e-01 6.24e-03
Disorders of transmembrane transporters 148 1.67e-03 1.50e-01 6.24e-03
Formation of ATP by chemiosmotic coupling 18 1.67e-03 4.28e-01 6.24e-03
Regulation of RUNX2 expression and activity 67 1.71e-03 2.22e-01 6.34e-03
Aquaporin-mediated transport 38 1.72e-03 2.94e-01 6.38e-03
Platelet Adhesion to exposed collagen 13 1.76e-03 5.01e-01 6.50e-03
Fc epsilon receptor (FCERI) signaling 191 1.77e-03 1.31e-01 6.52e-03
G1/S DNA Damage Checkpoints 66 1.79e-03 2.22e-01 6.57e-03
Regulation of actin dynamics for phagocytic cup formation 123 1.85e-03 1.62e-01 6.79e-03
Diseases of carbohydrate metabolism 29 1.86e-03 3.34e-01 6.81e-03
Vpr-mediated nuclear import of PICs 34 1.87e-03 -3.08e-01 6.81e-03
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 182 1.89e-03 -1.34e-01 6.84e-03
p53-Dependent G1 DNA Damage Response 64 1.89e-03 2.25e-01 6.84e-03
p53-Dependent G1/S DNA damage checkpoint 64 1.89e-03 2.25e-01 6.84e-03
tRNA modification in the nucleus and cytosol 43 1.92e-03 -2.73e-01 6.91e-03
Inflammasomes 20 1.92e-03 4.01e-01 6.91e-03
mTORC1-mediated signalling 23 1.96e-03 3.73e-01 7.04e-03
Signaling by Leptin 10 1.97e-03 5.65e-01 7.06e-03
Sema4D in semaphorin signaling 22 2.00e-03 3.80e-01 7.16e-03
Nuclear import of Rev protein 34 2.04e-03 -3.06e-01 7.25e-03
PLC beta mediated events 43 2.09e-03 2.71e-01 7.41e-03
Fcgamma receptor (FCGR) dependent phagocytosis 147 2.11e-03 1.47e-01 7.47e-03
Signaling by GPCR 545 2.12e-03 7.69e-02 7.50e-03
The NLRP3 inflammasome 15 2.13e-03 4.58e-01 7.50e-03
VLDLR internalisation and degradation 12 2.16e-03 5.11e-01 7.58e-03
Pentose phosphate pathway 13 2.26e-03 4.89e-01 7.93e-03
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15 2.30e-03 4.55e-01 8.04e-03
TAK1 activates NFkB by phosphorylation and activation of IKKs complex 27 2.38e-03 3.38e-01 8.29e-03
Pre-NOTCH Processing in Golgi 18 2.51e-03 4.11e-01 8.74e-03
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 54 2.55e-03 2.37e-01 8.77e-03
Constitutive Signaling by NOTCH1 PEST Domain Mutants 54 2.55e-03 2.37e-01 8.77e-03
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 54 2.55e-03 2.37e-01 8.77e-03
Signaling by NOTCH1 PEST Domain Mutants in Cancer 54 2.55e-03 2.37e-01 8.77e-03
Signaling by NOTCH1 in Cancer 54 2.55e-03 2.37e-01 8.77e-03
Glucagon signaling in metabolic regulation 27 2.63e-03 3.34e-01 9.00e-03
Interactions of Vpr with host cellular proteins 37 2.75e-03 -2.84e-01 9.32e-03
Cleavage of the damaged purine 24 2.75e-03 3.53e-01 9.32e-03
Depurination 24 2.75e-03 3.53e-01 9.32e-03
Recognition and association of DNA glycosylase with site containing an affected purine 24 2.75e-03 3.53e-01 9.32e-03
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane 22 2.81e-03 3.68e-01 9.50e-03
Regulation of APC/C activators between G1/S and early anaphase 80 2.83e-03 1.93e-01 9.55e-03
Signaling by TGFB family members 91 2.84e-03 1.81e-01 9.58e-03
Glycogen metabolism 23 2.91e-03 3.59e-01 9.79e-03
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 29 2.94e-03 3.19e-01 9.84e-03
IKK complex recruitment mediated by RIP1 23 2.99e-03 3.58e-01 9.99e-03
Formation of the cornified envelope 21 3.06e-03 3.73e-01 1.02e-02
Vasopressin regulates renal water homeostasis via Aquaporins 34 3.22e-03 2.92e-01 1.07e-02
GPCR downstream signalling 501 3.26e-03 7.68e-02 1.08e-02
Mitotic Anaphase 224 3.35e-03 1.14e-01 1.11e-02
IRAK1 recruits IKK complex 10 3.46e-03 5.34e-01 1.14e-02
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 10 3.46e-03 5.34e-01 1.14e-02
Cell recruitment (pro-inflammatory response) 22 3.47e-03 3.60e-01 1.14e-02
Purinergic signaling in leishmaniasis infection 22 3.47e-03 3.60e-01 1.14e-02
Death Receptor Signalling 132 3.50e-03 1.47e-01 1.15e-02
APC/C-mediated degradation of cell cycle proteins 87 3.52e-03 1.81e-01 1.15e-02
Regulation of mitotic cell cycle 87 3.52e-03 1.81e-01 1.15e-02
HDR through Single Strand Annealing (SSA) 37 3.61e-03 -2.76e-01 1.17e-02
G-protein mediated events 44 3.65e-03 2.53e-01 1.18e-02
MET activates RAP1 and RAC1 10 3.66e-03 5.31e-01 1.18e-02
Thromboxane signalling through TP receptor 20 3.68e-03 3.75e-01 1.19e-02
SARS-CoV-1 Infection 47 3.74e-03 2.44e-01 1.20e-02
Selective autophagy 58 3.80e-03 2.20e-01 1.22e-02
NOTCH4 Activation and Transmission of Signal to the Nucleus 10 3.85e-03 5.28e-01 1.23e-02
Processive synthesis on the lagging strand 15 3.88e-03 -4.31e-01 1.24e-02
SHC1 events in EGFR signaling 12 3.92e-03 4.81e-01 1.25e-02
G alpha (z) signalling events 36 4.07e-03 2.77e-01 1.29e-02
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) 12 4.12e-03 4.78e-01 1.30e-02
Diseases of hemostasis 12 4.12e-03 4.78e-01 1.30e-02
Signaling by EGFR in Cancer 23 4.22e-03 3.45e-01 1.33e-02
Antiviral mechanism by IFN-stimulated genes 80 4.28e-03 -1.85e-01 1.35e-02
Signaling by TGF-beta Receptor Complex 72 4.29e-03 1.95e-01 1.35e-02
Signaling by ERBB4 44 4.37e-03 2.48e-01 1.37e-02
M Phase 361 4.44e-03 8.72e-02 1.39e-02
Sema4D induced cell migration and growth-cone collapse 19 4.48e-03 3.77e-01 1.40e-02
Condensation of Prophase Chromosomes 29 4.54e-03 3.04e-01 1.41e-02
Export of Viral Ribonucleoproteins from Nucleus 33 4.60e-03 -2.85e-01 1.43e-02
Muscle contraction 142 4.62e-03 1.38e-01 1.43e-02
Plasma lipoprotein clearance 29 4.75e-03 3.03e-01 1.47e-02
Prolonged ERK activation events 13 4.76e-03 4.52e-01 1.47e-02
Apoptotic execution phase 45 4.77e-03 2.43e-01 1.47e-02
Trafficking of GluR2-containing AMPA receptors 12 4.79e-03 4.70e-01 1.47e-02
Mitotic Metaphase and Anaphase 225 4.82e-03 1.09e-01 1.47e-02
Disassembly of the destruction complex and recruitment of AXIN to the membrane 29 4.82e-03 3.02e-01 1.47e-02
Transport of Ribonucleoproteins into the Host Nucleus 32 4.86e-03 -2.88e-01 1.48e-02
WNT5A-dependent internalization of FZD4 13 5.02e-03 4.49e-01 1.53e-02
Assembly Of The HIV Virion 15 5.09e-03 4.18e-01 1.55e-02
LDL clearance 18 5.19e-03 3.81e-01 1.57e-02
Transport of Mature mRNA Derived from an Intronless Transcript 42 5.36e-03 -2.48e-01 1.62e-02
Cell surface interactions at the vascular wall 174 5.36e-03 1.22e-01 1.62e-02
Membrane binding and targetting of GAG proteins 13 5.40e-03 4.46e-01 1.62e-02
Synthesis And Processing Of GAG, GAGPOL Polyproteins 13 5.40e-03 4.46e-01 1.62e-02
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 36 5.50e-03 2.67e-01 1.65e-02
Cyclin E associated events during G1/S transition 83 5.53e-03 1.76e-01 1.65e-02
AKT phosphorylates targets in the cytosol 14 5.54e-03 4.28e-01 1.65e-02
ADP signalling through P2Y purinoceptor 12 18 5.56e-03 3.77e-01 1.66e-02
Transport of the SLBP independent Mature mRNA 35 5.65e-03 -2.70e-01 1.68e-02
Interleukin-10 signaling 35 5.66e-03 2.70e-01 1.68e-02
Uptake and actions of bacterial toxins 27 5.68e-03 3.07e-01 1.68e-02
Unfolded Protein Response (UPR) 87 5.84e-03 1.71e-01 1.73e-02
G alpha (i) signalling events 246 5.89e-03 1.02e-01 1.73e-02
Glycosaminoglycan metabolism 94 5.91e-03 1.64e-01 1.74e-02
GRB2 events in EGFR signaling 11 6.02e-03 4.78e-01 1.77e-02
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 11 6.19e-03 4.77e-01 1.81e-02
Intraflagellar transport 39 6.22e-03 -2.53e-01 1.82e-02
Activation of HOX genes during differentiation 69 6.52e-03 1.89e-01 1.89e-02
Activation of anterior HOX genes in hindbrain development during early embryogenesis 69 6.52e-03 1.89e-01 1.89e-02
Transport of bile salts and organic acids, metal ions and amine compounds 55 6.53e-03 2.12e-01 1.89e-02
RHO GTPases activate CIT 18 6.61e-03 3.70e-01 1.92e-02
G-protein activation 23 6.68e-03 3.27e-01 1.93e-02
ERKs are inactivated 13 6.71e-03 4.34e-01 1.93e-02
tRNA Aminoacylation 42 6.78e-03 -2.41e-01 1.95e-02
Stimuli-sensing channels 74 6.87e-03 1.82e-01 1.97e-02
Mitochondrial biogenesis 88 7.05e-03 1.66e-01 2.02e-02
Potential therapeutics for SARS 36 7.10e-03 2.59e-01 2.03e-02
GABA receptor activation 36 7.11e-03 2.59e-01 2.03e-02
Signaling by SCF-KIT 40 7.17e-03 2.46e-01 2.04e-02
Polymerase switching on the C-strand of the telomere 26 7.19e-03 -3.05e-01 2.04e-02
Synthesis of PC 23 7.24e-03 3.23e-01 2.05e-02
Activation of Matrix Metalloproteinases 23 7.33e-03 3.23e-01 2.08e-02
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 80 7.44e-03 1.73e-01 2.10e-02
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 32 7.55e-03 2.73e-01 2.13e-02
Interleukin-12 family signaling 53 7.67e-03 2.12e-01 2.16e-02
Syndecan interactions 19 7.70e-03 3.53e-01 2.16e-02
Gastrin-CREB signalling pathway via PKC and MAPK 14 7.84e-03 4.10e-01 2.20e-02
Activation of gene expression by SREBF (SREBP) 42 7.92e-03 2.37e-01 2.21e-02
TGF-beta receptor signaling activates SMADs 32 7.94e-03 2.71e-01 2.22e-02
ER Quality Control Compartment (ERQC) 21 7.99e-03 3.34e-01 2.22e-02
Erythropoietin activates RAS 13 8.13e-03 4.24e-01 2.26e-02
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 32 8.22e-03 -2.70e-01 2.27e-02
Regulation of Glucokinase by Glucokinase Regulatory Protein 32 8.22e-03 -2.70e-01 2.27e-02
GTP hydrolysis and joining of the 60S ribosomal subunit 111 8.23e-03 -1.45e-01 2.27e-02
Caspase activation via extrinsic apoptotic signalling pathway 25 8.38e-03 3.05e-01 2.31e-02
Glycosphingolipid metabolism 36 8.40e-03 2.54e-01 2.31e-02
Signaling by FGFR3 31 8.41e-03 2.73e-01 2.31e-02
Suppression of phagosomal maturation 12 8.51e-03 4.39e-01 2.33e-02
Negative regulation of FGFR3 signaling 20 8.81e-03 3.38e-01 2.40e-02
Hedgehog 'off' state 93 8.83e-03 1.57e-01 2.40e-02
Mucopolysaccharidoses 11 8.83e-03 4.56e-01 2.40e-02
Interleukin-3, Interleukin-5 and GM-CSF signaling 40 8.86e-03 2.39e-01 2.41e-02
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 36 8.91e-03 2.52e-01 2.42e-02
Activation of GABAB receptors 31 8.98e-03 2.71e-01 2.42e-02
GABA B receptor activation 31 8.98e-03 2.71e-01 2.42e-02
MET promotes cell motility 26 9.05e-03 2.96e-01 2.44e-02
Beta-catenin phosphorylation cascade 17 9.11e-03 3.65e-01 2.45e-02
Integrin cell surface interactions 52 9.18e-03 2.09e-01 2.46e-02
Effects of PIP2 hydrolysis 24 9.24e-03 -3.07e-01 2.48e-02
FCGR3A-mediated phagocytosis 121 9.35e-03 1.37e-01 2.49e-02
Leishmania phagocytosis 121 9.35e-03 1.37e-01 2.49e-02
Parasite infection 121 9.35e-03 1.37e-01 2.49e-02
Intra-Golgi traffic 43 9.48e-03 2.29e-01 2.52e-02
Collagen formation 66 9.52e-03 1.85e-01 2.53e-02
Transport of Mature mRNAs Derived from Intronless Transcripts 43 9.62e-03 -2.28e-01 2.55e-02
Removal of the Flap Intermediate 14 9.82e-03 -3.99e-01 2.60e-02
Josephin domain DUBs 10 9.89e-03 4.71e-01 2.61e-02
Assembly of the pre-replicative complex 67 9.99e-03 1.82e-01 2.63e-02
Endogenous sterols 17 1.00e-02 3.61e-01 2.64e-02
Glycogen breakdown (glycogenolysis) 13 1.01e-02 4.12e-01 2.64e-02
G beta:gamma signalling through CDC42 17 1.02e-02 3.60e-01 2.66e-02
Regulation of IFNG signaling 14 1.04e-02 3.96e-01 2.71e-02
Prefoldin mediated transfer of substrate to CCT/TriC 26 1.04e-02 2.90e-01 2.71e-02
Cleavage of the damaged pyrimidine 29 1.04e-02 2.75e-01 2.71e-02
Depyrimidination 29 1.04e-02 2.75e-01 2.71e-02
Recognition and association of DNA glycosylase with site containing an affected pyrimidine 29 1.04e-02 2.75e-01 2.71e-02
L13a-mediated translational silencing of Ceruloplasmin expression 110 1.05e-02 -1.41e-01 2.73e-02
TNFR2 non-canonical NF-kB pathway 96 1.06e-02 1.51e-01 2.74e-02
HCMV Infection 96 1.07e-02 1.51e-01 2.74e-02
Protein localization 157 1.07e-02 1.18e-01 2.74e-02
Gap junction trafficking and regulation 16 1.08e-02 3.68e-01 2.76e-02
Transport of the SLBP Dependant Mature mRNA 36 1.08e-02 -2.46e-01 2.76e-02
Cristae formation 31 1.08e-02 2.65e-01 2.76e-02
Cyclin A:Cdk2-associated events at S phase entry 85 1.09e-02 1.60e-01 2.79e-02
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 11 1.09e-02 4.43e-01 2.79e-02
Signaling by NOTCH3 43 1.11e-02 2.24e-01 2.83e-02
MAP3K8 (TPL2)-dependent MAPK1/3 activation 16 1.11e-02 3.67e-01 2.83e-02
Negative regulation of FGFR1 signaling 24 1.12e-02 2.99e-01 2.83e-02
Formation of Fibrin Clot (Clotting Cascade) 26 1.12e-02 2.87e-01 2.84e-02
TRAF6-mediated induction of TAK1 complex within TLR4 complex 16 1.15e-02 3.65e-01 2.89e-02
Metabolism of porphyrins 22 1.15e-02 3.11e-01 2.90e-02
Biotin transport and metabolism 11 1.16e-02 -4.40e-01 2.91e-02
Glycogen synthesis 13 1.16e-02 4.04e-01 2.91e-02
Pyruvate metabolism and Citric Acid (TCA) cycle 52 1.19e-02 2.02e-01 2.98e-02
Alpha-protein kinase 1 signaling pathway 11 1.19e-02 4.38e-01 2.99e-02
Nucleotide salvage 21 1.20e-02 3.17e-01 3.00e-02
ATF6 (ATF6-alpha) activates chaperones 12 1.23e-02 4.17e-01 3.07e-02
RHO GTPases activate IQGAPs 11 1.26e-02 4.34e-01 3.13e-02
Formation of the beta-catenin:TCF transactivating complex 46 1.26e-02 2.13e-01 3.13e-02
Negative regulation of FGFR4 signaling 21 1.27e-02 3.14e-01 3.15e-02
Signaling by FGFR4 31 1.28e-02 2.58e-01 3.16e-02
Metabolism of steroid hormones 21 1.32e-02 3.12e-01 3.27e-02
Circadian Clock 67 1.37e-02 1.74e-01 3.37e-02
Estrogen-dependent nuclear events downstream of ESR-membrane signaling 22 1.37e-02 3.03e-01 3.38e-02
RNA Polymerase I Transcription Initiation 47 1.38e-02 -2.07e-01 3.40e-02
Mitochondrial tRNA aminoacylation 21 1.39e-02 -3.10e-01 3.40e-02
VxPx cargo-targeting to cilium 19 1.40e-02 3.25e-01 3.44e-02
Signal regulatory protein family interactions 12 1.44e-02 4.08e-01 3.51e-02
ATF6 (ATF6-alpha) activates chaperone genes 10 1.44e-02 4.47e-01 3.52e-02
G beta:gamma signalling through PLC beta 17 1.48e-02 3.41e-01 3.60e-02
SUMOylation of DNA damage response and repair proteins 77 1.48e-02 -1.61e-01 3.61e-02
Base-Excision Repair, AP Site Formation 31 1.50e-02 2.52e-01 3.62e-02
Cap-dependent Translation Initiation 118 1.50e-02 -1.30e-01 3.62e-02
Eukaryotic Translation Initiation 118 1.50e-02 -1.30e-01 3.62e-02
EPH-ephrin mediated repulsion of cells 40 1.52e-02 2.22e-01 3.66e-02
HCMV Late Events 69 1.53e-02 1.69e-01 3.70e-02
Interleukin-12 signaling 44 1.54e-02 2.11e-01 3.71e-02
Activated NOTCH1 Transmits Signal to the Nucleus 27 1.58e-02 2.68e-01 3.79e-02
SRP-dependent cotranslational protein targeting to membrane 111 1.62e-02 -1.32e-01 3.88e-02
CD28 dependent PI3K/Akt signaling 22 1.64e-02 -2.96e-01 3.92e-02
NGF-stimulated transcription 31 1.64e-02 2.49e-01 3.92e-02
Regulated proteolysis of p75NTR 11 1.65e-02 4.18e-01 3.92e-02
G alpha (12/13) signalling events 69 1.67e-02 1.67e-01 3.98e-02
Response of EIF2AK1 (HRI) to heme deficiency 14 1.68e-02 3.69e-01 4.00e-02
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression 32 1.70e-02 2.44e-01 4.04e-02
DNA Repair 289 1.71e-02 -8.15e-02 4.04e-02
Peroxisomal protein import 57 1.71e-02 1.83e-01 4.04e-02
Cell-Cell communication 89 1.71e-02 1.46e-01 4.05e-02
Cell-extracellular matrix interactions 14 1.73e-02 3.68e-01 4.07e-02
Sphingolipid de novo biosynthesis 41 1.78e-02 2.14e-01 4.18e-02
SIRT1 negatively regulates rRNA expression 24 1.78e-02 2.79e-01 4.18e-02
RNA Polymerase III Transcription Initiation From Type 1 Promoter 28 1.78e-02 -2.59e-01 4.18e-02
Presynaptic function of Kainate receptors 18 1.80e-02 3.22e-01 4.21e-02
Leading Strand Synthesis 14 1.83e-02 -3.64e-01 4.26e-02
Polymerase switching 14 1.83e-02 -3.64e-01 4.26e-02
Postmitotic nuclear pore complex (NPC) reformation 27 1.83e-02 -2.62e-01 4.26e-02
SUMOylation of immune response proteins 11 1.84e-02 4.11e-01 4.26e-02
SLC-mediated transmembrane transport 180 1.84e-02 1.02e-01 4.26e-02
Cell junction organization 60 1.85e-02 1.76e-01 4.28e-02
Formation of tubulin folding intermediates by CCT/TriC 22 1.87e-02 2.90e-01 4.32e-02
HDR through MMEJ (alt-NHEJ) 10 1.89e-02 -4.29e-01 4.36e-02
G beta:gamma signalling through PI3Kgamma 22 1.93e-02 2.88e-01 4.46e-02
Cilium Assembly 181 1.95e-02 -1.01e-01 4.48e-02
Translation of Replicase and Assembly of the Replication Transcription Complex 12 1.98e-02 3.88e-01 4.55e-02
Keratinization 33 2.01e-02 2.34e-01 4.62e-02
Activation of G protein gated Potassium channels 20 2.03e-02 3.00e-01 4.62e-02
G protein gated Potassium channels 20 2.03e-02 3.00e-01 4.62e-02
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 20 2.03e-02 3.00e-01 4.62e-02
Butyrophilin (BTN) family interactions 10 2.05e-02 -4.23e-01 4.67e-02
Apoptotic factor-mediated response 18 2.10e-02 3.14e-01 4.77e-02
Ca-dependent events 29 2.11e-02 2.47e-01 4.79e-02
FOXO-mediated transcription of cell death genes 16 2.16e-02 3.32e-01 4.89e-02
RORA activates gene expression 18 2.17e-02 3.12e-01 4.91e-02
Regulation of PTEN gene transcription 59 2.23e-02 1.72e-01 5.03e-02
Transport of Mature mRNA derived from an Intron-Containing Transcript 72 2.30e-02 -1.55e-01 5.19e-02
Interferon gamma signaling 83 2.32e-02 -1.44e-01 5.23e-02
Nucleobase catabolism 28 2.33e-02 2.48e-01 5.23e-02
TRAF6 mediated NF-kB activation 23 2.38e-02 2.72e-01 5.34e-02
Negative regulation of the PI3K/AKT network 87 2.39e-02 1.40e-01 5.36e-02
Oncogene Induced Senescence 33 2.40e-02 2.27e-01 5.37e-02
Metabolism of Angiotensinogen to Angiotensins 11 2.43e-02 3.92e-01 5.41e-02
HuR (ELAVL1) binds and stabilizes mRNA 10 2.45e-02 4.11e-01 5.46e-02
Telomere C-strand synthesis initiation 13 2.45e-02 -3.60e-01 5.46e-02
PKA activation in glucagon signalling 14 2.47e-02 3.47e-01 5.48e-02
Pyruvate metabolism 28 2.48e-02 2.45e-01 5.51e-02
RHO GTPases activate KTN1 11 2.49e-02 3.91e-01 5.51e-02
RNA Polymerase III Transcription Initiation From Type 2 Promoter 27 2.59e-02 -2.48e-01 5.72e-02
ISG15 antiviral mechanism 72 2.60e-02 -1.52e-01 5.75e-02
Gluconeogenesis 28 2.62e-02 2.43e-01 5.77e-02
Nucleobase biosynthesis 13 2.64e-02 -3.56e-01 5.82e-02
NOD1/2 Signaling Pathway 32 2.68e-02 2.26e-01 5.88e-02
Heme degradation 10 2.73e-02 4.03e-01 5.99e-02
Formation of apoptosome 11 2.75e-02 3.84e-01 6.00e-02
Regulation of the apoptosome activity 11 2.75e-02 3.84e-01 6.00e-02
Triglyceride catabolism 16 2.79e-02 3.17e-01 6.09e-02
Interleukin-6 signaling 10 2.81e-02 4.01e-01 6.13e-02
NOTCH3 Activation and Transmission of Signal to the Nucleus 23 2.83e-02 2.64e-01 6.14e-02
O-glycosylation of TSR domain-containing proteins 27 2.83e-02 -2.44e-01 6.14e-02
DNA Damage/Telomere Stress Induced Senescence 44 2.85e-02 1.91e-01 6.18e-02
Citric acid cycle (TCA cycle) 22 2.86e-02 2.70e-01 6.20e-02
Arachidonic acid metabolism 43 2.93e-02 1.92e-01 6.33e-02
Regulation of TP53 Activity 152 2.96e-02 -1.02e-01 6.39e-02
Common Pathway of Fibrin Clot Formation 14 2.97e-02 3.36e-01 6.41e-02
Diseases associated with O-glycosylation of proteins 49 2.98e-02 -1.79e-01 6.41e-02
Frs2-mediated activation 11 3.00e-02 3.78e-01 6.44e-02
G beta:gamma signalling through BTK 15 3.01e-02 3.23e-01 6.45e-02
Negative regulation of MAPK pathway 42 3.02e-02 1.93e-01 6.47e-02
SUMOylation of SUMOylation proteins 35 3.02e-02 -2.12e-01 6.47e-02
Myogenesis 21 3.11e-02 2.72e-01 6.64e-02
Peptide hormone metabolism 50 3.13e-02 1.76e-01 6.66e-02
Retrograde transport at the Trans-Golgi-Network 49 3.17e-02 1.77e-01 6.74e-02
SUMOylation of RNA binding proteins 47 3.20e-02 -1.81e-01 6.79e-02
Activation of the AP-1 family of transcription factors 10 3.25e-02 3.90e-01 6.90e-02
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 26 3.26e-02 -2.42e-01 6.90e-02
Signalling to RAS 19 3.27e-02 2.83e-01 6.91e-02
Diseases associated with glycosylation precursor biosynthesis 18 3.27e-02 2.91e-01 6.91e-02
Cytochrome c-mediated apoptotic response 13 3.33e-02 3.41e-01 7.02e-02
Metalloprotease DUBs 21 3.33e-02 2.68e-01 7.02e-02
Cell death signalling via NRAGE, NRIF and NADE 70 3.34e-02 1.47e-01 7.02e-02
Signaling by FGFR1 38 3.40e-02 1.99e-01 7.13e-02
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 16 3.42e-02 3.06e-01 7.17e-02
Post-chaperonin tubulin folding pathway 19 3.43e-02 2.80e-01 7.18e-02
FCGR activation 76 3.45e-02 -1.40e-01 7.20e-02
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 17 3.50e-02 2.95e-01 7.30e-02
Transcriptional Regulation by E2F6 34 3.52e-02 -2.09e-01 7.32e-02
FCERI mediated NF-kB activation 138 3.53e-02 1.04e-01 7.35e-02
Transport of Mature Transcript to Cytoplasm 81 3.56e-02 -1.35e-01 7.40e-02
The role of Nef in HIV-1 replication and disease pathogenesis 28 3.58e-02 2.29e-01 7.43e-02
DAP12 interactions 39 3.59e-02 1.94e-01 7.44e-02
NR1H2 and NR1H3-mediated signaling 39 3.61e-02 1.94e-01 7.47e-02
Separation of Sister Chromatids 168 3.62e-02 9.36e-02 7.48e-02
Activation of BAD and translocation to mitochondria 15 3.69e-02 3.11e-01 7.60e-02
Apoptosis induced DNA fragmentation 10 3.79e-02 3.79e-01 7.80e-02
Nuclear signaling by ERBB4 24 3.90e-02 2.43e-01 8.01e-02
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 18 3.97e-02 2.80e-01 8.13e-02
Signaling by Ligand-Responsive EGFR Variants in Cancer 18 3.97e-02 2.80e-01 8.13e-02
Pexophagy 11 4.02e-02 3.57e-01 8.22e-02
Intrinsic Pathway for Apoptosis 53 4.03e-02 1.63e-01 8.24e-02
Biological oxidations 138 4.10e-02 1.01e-01 8.37e-02
Translesion synthesis by REV1 16 4.13e-02 -2.95e-01 8.40e-02
DNA Double-Strand Break Repair 135 4.22e-02 -1.01e-01 8.58e-02
Defects in vitamin and cofactor metabolism 21 4.23e-02 -2.56e-01 8.58e-02
Mitotic G2-G2/M phases 183 4.27e-02 8.69e-02 8.65e-02
Mitotic Prophase 98 4.33e-02 1.18e-01 8.77e-02
Termination of translesion DNA synthesis 32 4.40e-02 -2.06e-01 8.89e-02
RNA Polymerase II Pre-transcription Events 78 4.41e-02 1.32e-01 8.89e-02
Meiotic synapsis 45 4.48e-02 1.73e-01 9.03e-02
SHC1 events in ERBB2 signaling 17 4.54e-02 2.80e-01 9.13e-02
Diseases of DNA repair 10 4.55e-02 -3.65e-01 9.13e-02
HDMs demethylate histones 22 4.64e-02 2.45e-01 9.30e-02
Biosynthesis of specialized proresolving mediators (SPMs) 16 4.64e-02 2.88e-01 9.30e-02
Aggrephagy 22 4.66e-02 2.45e-01 9.32e-02
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 14 4.78e-02 -3.06e-01 9.53e-02
Surfactant metabolism 22 4.79e-02 2.44e-01 9.53e-02
Formation of RNA Pol II elongation complex 57 4.80e-02 1.51e-01 9.53e-02
RNA Polymerase II Transcription Elongation 57 4.80e-02 1.51e-01 9.53e-02
Elastic fibre formation 32 4.85e-02 2.01e-01 9.64e-02
p75NTR signals via NF-kB 15 4.88e-02 2.94e-01 9.68e-02
GP1b-IX-V activation signalling 10 5.04e-02 3.57e-01 9.97e-02
Defective B3GALTL causes Peters-plus syndrome (PpS) 26 5.11e-02 -2.21e-01 1.01e-01
MET activates RAS signaling 10 5.12e-02 3.56e-01 1.01e-01
RET signaling 32 5.21e-02 1.98e-01 1.03e-01
Initiation of Nuclear Envelope (NE) Reformation 19 5.27e-02 2.57e-01 1.04e-01
Misspliced GSK3beta mutants stabilize beta-catenin 15 5.33e-02 2.88e-01 1.04e-01
S33 mutants of beta-catenin aren't phosphorylated 15 5.33e-02 2.88e-01 1.04e-01
S37 mutants of beta-catenin aren't phosphorylated 15 5.33e-02 2.88e-01 1.04e-01
S45 mutants of beta-catenin aren't phosphorylated 15 5.33e-02 2.88e-01 1.04e-01
T41 mutants of beta-catenin aren't phosphorylated 15 5.33e-02 2.88e-01 1.04e-01
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 15 5.33e-02 2.88e-01 1.04e-01
Sialic acid metabolism 28 5.34e-02 2.11e-01 1.04e-01
Nuclear Pore Complex (NPC) Disassembly 36 5.36e-02 -1.86e-01 1.04e-01
Signaling by ERBB2 44 5.38e-02 1.68e-01 1.05e-01
Gap-filling DNA repair synthesis and ligation in GG-NER 25 5.39e-02 -2.23e-01 1.05e-01
Laminin interactions 21 5.43e-02 2.43e-01 1.05e-01
SUMOylation of ubiquitinylation proteins 39 5.48e-02 -1.78e-01 1.06e-01
Regulation of signaling by CBL 18 5.52e-02 2.61e-01 1.06e-01
Processive synthesis on the C-strand of the telomere 19 5.52e-02 -2.54e-01 1.06e-01
Metabolism of fat-soluble vitamins 28 5.67e-02 2.08e-01 1.09e-01
NoRC negatively regulates rRNA expression 62 5.70e-02 1.40e-01 1.10e-01
Orc1 removal from chromatin 70 5.76e-02 1.31e-01 1.11e-01
Synthesis of Leukotrienes (LT) and Eoxins (EX) 15 5.77e-02 2.83e-01 1.11e-01
TNFR1-induced proapoptotic signaling 12 5.78e-02 -3.16e-01 1.11e-01
Trafficking and processing of endosomal TLR 13 5.88e-02 3.03e-01 1.12e-01
Pyrimidine salvage 10 5.91e-02 3.45e-01 1.13e-01
Chromosome Maintenance 105 5.92e-02 -1.07e-01 1.13e-01
Rap1 signalling 13 5.95e-02 3.02e-01 1.13e-01
Classical antibody-mediated complement activation 69 5.97e-02 -1.31e-01 1.14e-01
Glycogen storage diseases 13 6.01e-02 3.01e-01 1.14e-01
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13 6.05e-02 3.01e-01 1.15e-01
Signaling by the B Cell Receptor (BCR) 163 6.05e-02 8.52e-02 1.15e-01
TICAM1, RIP1-mediated IKK complex recruitment 19 6.09e-02 2.48e-01 1.15e-01
Constitutive Signaling by EGFRvIII 14 6.17e-02 2.88e-01 1.16e-01
Signaling by EGFRvIII in Cancer 14 6.17e-02 2.88e-01 1.16e-01
Intrinsic Pathway of Fibrin Clot Formation 16 6.18e-02 2.70e-01 1.16e-01
p38MAPK events 13 6.19e-02 2.99e-01 1.17e-01
Translesion synthesis by POLI 17 6.22e-02 -2.61e-01 1.17e-01
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 33 6.33e-02 1.87e-01 1.19e-01
Downregulation of ERBB2 signaling 24 6.39e-02 2.18e-01 1.20e-01
G2/M Transition 181 6.42e-02 7.98e-02 1.20e-01
cGMP effects 13 6.42e-02 2.96e-01 1.20e-01
FGFR1 mutant receptor activation 24 6.47e-02 2.18e-01 1.21e-01
G alpha (q) signalling events 134 6.48e-02 9.24e-02 1.21e-01
SUMOylation of chromatin organization proteins 57 6.56e-02 -1.41e-01 1.22e-01
FOXO-mediated transcription 59 6.72e-02 1.38e-01 1.25e-01
Regulation of TP53 Activity through Acetylation 29 6.76e-02 -1.96e-01 1.25e-01
SHC1 events in ERBB4 signaling 10 6.80e-02 3.33e-01 1.26e-01
Prostacyclin signalling through prostacyclin receptor 16 6.82e-02 2.63e-01 1.26e-01
Dual Incision in GG-NER 41 6.86e-02 -1.64e-01 1.27e-01
Tie2 Signaling 16 7.05e-02 2.61e-01 1.30e-01
Caspase activation via Death Receptors in the presence of ligand 16 7.20e-02 2.60e-01 1.33e-01
Signaling by cytosolic FGFR1 fusion mutants 18 7.23e-02 2.45e-01 1.33e-01
CaM pathway 27 7.26e-02 2.00e-01 1.33e-01
Calmodulin induced events 27 7.26e-02 2.00e-01 1.33e-01
EPHA-mediated growth cone collapse 13 7.31e-02 2.87e-01 1.34e-01
PKA activation 15 7.31e-02 2.67e-01 1.34e-01
PRC2 methylates histones and DNA 29 7.36e-02 1.92e-01 1.35e-01
Retinoid metabolism and transport 24 7.37e-02 2.11e-01 1.35e-01
Chondroitin sulfate biosynthesis 12 7.62e-02 2.96e-01 1.39e-01
Negative regulation of FGFR2 signaling 23 7.66e-02 2.13e-01 1.39e-01
RNA Polymerase III Transcription Initiation 36 7.66e-02 -1.71e-01 1.39e-01
Insulin receptor signalling cascade 39 7.68e-02 1.64e-01 1.39e-01
SUMOylation of intracellular receptors 26 7.68e-02 2.00e-01 1.39e-01
Acyl chain remodelling of PC 19 7.71e-02 2.34e-01 1.39e-01
BMAL1:CLOCK,NPAS2 activates circadian gene expression 25 7.71e-02 2.04e-01 1.39e-01
Striated Muscle Contraction 24 7.76e-02 2.08e-01 1.40e-01
Inwardly rectifying K+ channels 24 7.79e-02 2.08e-01 1.41e-01
Resolution of D-Loop Structures 33 7.85e-02 -1.77e-01 1.41e-01
Apoptotic cleavage of cellular proteins 34 7.85e-02 1.74e-01 1.41e-01
Metabolism of nucleotides 86 7.90e-02 1.10e-01 1.42e-01
Transcriptional Regulation by MECP2 47 8.13e-02 1.47e-01 1.46e-01
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 18 8.14e-02 2.37e-01 1.46e-01
Signaling by Hippo 18 8.17e-02 2.37e-01 1.46e-01
ERBB2 Regulates Cell Motility 10 8.23e-02 3.17e-01 1.47e-01
Listeria monocytogenes entry into host cells 17 8.25e-02 2.43e-01 1.47e-01
CD22 mediated BCR regulation 59 8.26e-02 -1.31e-01 1.47e-01
Signaling by ERBB2 in Cancer 21 8.27e-02 2.19e-01 1.47e-01
Attenuation phase 23 8.28e-02 2.09e-01 1.47e-01
Creation of C4 and C2 activators 71 8.33e-02 -1.19e-01 1.48e-01
Signaling by PDGFRA extracellular domain mutants 12 8.43e-02 2.88e-01 1.49e-01
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants 12 8.43e-02 2.88e-01 1.49e-01
Mitotic Telophase/Cytokinesis 13 8.47e-02 2.76e-01 1.50e-01
PI Metabolism 80 8.53e-02 1.11e-01 1.51e-01
Translesion synthesis by POLK 17 8.56e-02 -2.41e-01 1.51e-01
Glucose metabolism 84 8.62e-02 1.08e-01 1.52e-01
Role of phospholipids in phagocytosis 88 8.64e-02 -1.06e-01 1.52e-01
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol 16 8.67e-02 2.47e-01 1.52e-01
Initial triggering of complement 78 8.68e-02 -1.12e-01 1.52e-01
Downregulation of TGF-beta receptor signaling 26 8.73e-02 1.94e-01 1.53e-01
Synthesis of substrates in N-glycan biosythesis 58 8.82e-02 1.29e-01 1.54e-01
Resolution of D-loop Structures through Holliday Junction Intermediates 32 8.89e-02 -1.74e-01 1.55e-01
Synthesis of PIPs at the plasma membrane 52 8.98e-02 1.36e-01 1.57e-01
Mitophagy 28 8.99e-02 1.85e-01 1.57e-01
SUMOylation of DNA replication proteins 46 9.14e-02 -1.44e-01 1.59e-01
Collagen biosynthesis and modifying enzymes 48 9.20e-02 1.41e-01 1.60e-01
B-WICH complex positively regulates rRNA expression 47 9.33e-02 1.41e-01 1.62e-01
Nuclear Envelope (NE) Reassembly 69 9.41e-02 1.17e-01 1.63e-01
AMER1 mutants destabilize the destruction complex 14 9.52e-02 2.58e-01 1.64e-01
APC truncation mutants have impaired AXIN binding 14 9.52e-02 2.58e-01 1.64e-01
AXIN missense mutants destabilize the destruction complex 14 9.52e-02 2.58e-01 1.64e-01
AXIN mutants destabilize the destruction complex, activating WNT signaling 14 9.52e-02 2.58e-01 1.64e-01
Truncations of AMER1 destabilize the destruction complex 14 9.52e-02 2.58e-01 1.64e-01
truncated APC mutants destabilize the destruction complex 14 9.52e-02 2.58e-01 1.64e-01
Receptor Mediated Mitophagy 11 9.58e-02 2.90e-01 1.65e-01
Chaperone Mediated Autophagy 20 9.61e-02 2.15e-01 1.65e-01
Acyl chain remodelling of PI 10 9.74e-02 3.03e-01 1.67e-01
NOTCH3 Intracellular Domain Regulates Transcription 21 9.74e-02 2.09e-01 1.67e-01
Signaling by FGFR1 in disease 31 9.76e-02 1.72e-01 1.67e-01
Metabolism of nitric oxide: NOS3 activation and regulation 12 9.79e-02 2.76e-01 1.67e-01
Potassium Channels 64 9.86e-02 1.19e-01 1.68e-01
Plasma lipoprotein remodeling 18 9.94e-02 2.24e-01 1.69e-01
HIV Transcription Initiation 45 9.99e-02 1.42e-01 1.69e-01
RNA Polymerase II HIV Promoter Escape 45 9.99e-02 1.42e-01 1.69e-01
RNA Polymerase II Promoter Escape 45 9.99e-02 1.42e-01 1.69e-01
RNA Polymerase II Transcription Initiation 45 9.99e-02 1.42e-01 1.69e-01
RNA Polymerase II Transcription Initiation And Promoter Clearance 45 9.99e-02 1.42e-01 1.69e-01
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 45 9.99e-02 1.42e-01 1.69e-01
RNA polymerase II transcribes snRNA genes 72 1.01e-01 1.12e-01 1.70e-01
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 14 1.01e-01 -2.53e-01 1.70e-01
Chemokine receptors bind chemokines 39 1.03e-01 -1.51e-01 1.74e-01
Triglyceride metabolism 25 1.05e-01 1.87e-01 1.76e-01
Mismatch Repair 15 1.06e-01 -2.41e-01 1.78e-01
Switching of origins to a post-replicative state 90 1.07e-01 9.84e-02 1.79e-01
Homology Directed Repair 110 1.07e-01 -8.89e-02 1.80e-01
Nitric oxide stimulates guanylate cyclase 16 1.07e-01 2.32e-01 1.80e-01
mRNA decay by 3' to 5' exoribonuclease 16 1.07e-01 -2.32e-01 1.80e-01
TICAM1,TRAF6-dependent induction of TAK1 complex 11 1.08e-01 2.80e-01 1.80e-01
Activation of kainate receptors upon glutamate binding 26 1.08e-01 1.82e-01 1.80e-01
PI3K/AKT Signaling in Cancer 81 1.08e-01 1.03e-01 1.80e-01
Insulin processing 21 1.09e-01 2.02e-01 1.82e-01
Pausing and recovery of Tat-mediated HIV elongation 30 1.10e-01 1.69e-01 1.82e-01
Tat-mediated HIV elongation arrest and recovery 30 1.10e-01 1.69e-01 1.82e-01
Translation 295 1.10e-01 -5.41e-02 1.83e-01
MASTL Facilitates Mitotic Progression 10 1.10e-01 2.92e-01 1.83e-01
NF-kB is activated and signals survival 12 1.11e-01 2.66e-01 1.83e-01
Mitochondrial iron-sulfur cluster biogenesis 13 1.11e-01 2.55e-01 1.84e-01
Signaling by PDGF 44 1.12e-01 1.39e-01 1.84e-01
Host Interactions of HIV factors 130 1.12e-01 8.07e-02 1.84e-01
Interleukin-27 signaling 11 1.12e-01 2.77e-01 1.84e-01
Phase II - Conjugation of compounds 68 1.13e-01 1.11e-01 1.86e-01
BBSome-mediated cargo-targeting to cilium 22 1.14e-01 -1.94e-01 1.88e-01
Heme biosynthesis 14 1.15e-01 2.43e-01 1.89e-01
Scavenging by Class A Receptors 12 1.18e-01 2.61e-01 1.93e-01
HIV elongation arrest and recovery 32 1.18e-01 1.60e-01 1.93e-01
Pausing and recovery of HIV elongation 32 1.18e-01 1.60e-01 1.93e-01
RNA Polymerase I Promoter Escape 47 1.18e-01 1.32e-01 1.93e-01
Glutathione conjugation 26 1.18e-01 1.77e-01 1.93e-01
Peroxisomal lipid metabolism 27 1.19e-01 1.74e-01 1.93e-01
Recognition of DNA damage by PCNA-containing replication complex 30 1.19e-01 -1.65e-01 1.93e-01
Depolymerisation of the Nuclear Lamina 15 1.19e-01 2.32e-01 1.93e-01
Class C/3 (Metabotropic glutamate/pheromone receptors) 11 1.19e-01 -2.71e-01 1.94e-01
Assembly of collagen fibrils and other multimeric structures 42 1.20e-01 1.39e-01 1.94e-01
TP53 Regulates Transcription of Cell Death Genes 43 1.20e-01 1.37e-01 1.94e-01
O-linked glycosylation of mucins 47 1.21e-01 1.31e-01 1.96e-01
Fatty acyl-CoA biosynthesis 35 1.21e-01 1.51e-01 1.96e-01
Interleukin-15 signaling 14 1.22e-01 2.38e-01 1.98e-01
Carnitine metabolism 10 1.23e-01 2.82e-01 1.98e-01
Phase I - Functionalization of compounds 65 1.24e-01 1.10e-01 2.00e-01
Signaling by FGFR in disease 51 1.25e-01 1.24e-01 2.01e-01
Removal of the Flap Intermediate from the C-strand 17 1.25e-01 -2.15e-01 2.01e-01
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 21 1.26e-01 1.93e-01 2.03e-01
Beta-oxidation of very long chain fatty acids 10 1.28e-01 2.78e-01 2.04e-01
Interleukin-6 family signaling 18 1.30e-01 2.06e-01 2.09e-01
Glycolysis 67 1.32e-01 1.06e-01 2.11e-01
rRNA processing in the mitochondrion 29 1.34e-01 -1.61e-01 2.14e-01
Regulation of TP53 Activity through Phosphorylation 88 1.35e-01 -9.21e-02 2.16e-01
PINK1-PRKN Mediated Mitophagy 21 1.35e-01 1.88e-01 2.16e-01
p75NTR recruits signalling complexes 12 1.36e-01 2.49e-01 2.16e-01
Carboxyterminal post-translational modifications of tubulin 27 1.37e-01 1.65e-01 2.18e-01
NCAM1 interactions 23 1.39e-01 -1.78e-01 2.20e-01
ZBP1(DAI) mediated induction of type I IFNs 20 1.39e-01 1.91e-01 2.21e-01
Transport of vitamins, nucleosides, and related molecules 33 1.41e-01 1.48e-01 2.23e-01
Viral Messenger RNA Synthesis 44 1.42e-01 -1.28e-01 2.24e-01
Downstream signal transduction 27 1.42e-01 1.63e-01 2.25e-01
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 14 1.44e-01 2.26e-01 2.27e-01
NRIF signals cell death from the nucleus 15 1.45e-01 2.18e-01 2.28e-01
Acyl chain remodelling of PE 20 1.45e-01 1.88e-01 2.29e-01
Phase 0 - rapid depolarisation 28 1.46e-01 -1.59e-01 2.30e-01
Purine ribonucleoside monophosphate biosynthesis 10 1.47e-01 -2.65e-01 2.31e-01
Peptide ligand-binding receptors 97 1.47e-01 8.52e-02 2.31e-01
Bile acid and bile salt metabolism 28 1.49e-01 1.58e-01 2.33e-01
Metabolism of cofactors 19 1.49e-01 1.91e-01 2.33e-01
CD209 (DC-SIGN) signaling 20 1.50e-01 1.86e-01 2.34e-01
Ca2+ pathway 57 1.50e-01 1.10e-01 2.34e-01
Signaling by ERBB2 KD Mutants 20 1.50e-01 1.86e-01 2.34e-01
RA biosynthesis pathway 13 1.50e-01 -2.30e-01 2.34e-01
Negative epigenetic regulation of rRNA expression 65 1.52e-01 1.03e-01 2.37e-01
PI3K events in ERBB2 signaling 11 1.53e-01 2.49e-01 2.38e-01
Constitutive Signaling by AKT1 E17K in Cancer 26 1.55e-01 1.61e-01 2.40e-01
Amine ligand-binding receptors 10 1.55e-01 -2.60e-01 2.40e-01
Constitutive Signaling by Overexpressed ERBB2 11 1.55e-01 2.48e-01 2.40e-01
tRNA processing in the mitochondrion 32 1.55e-01 -1.45e-01 2.40e-01
Synthesis of very long-chain fatty acyl-CoAs 22 1.56e-01 1.75e-01 2.42e-01
GRB2 events in ERBB2 signaling 11 1.58e-01 2.46e-01 2.44e-01
RIP-mediated NFkB activation via ZBP1 17 1.60e-01 1.97e-01 2.46e-01
Formation of TC-NER Pre-Incision Complex 53 1.61e-01 1.11e-01 2.48e-01
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein 73 1.62e-01 9.47e-02 2.49e-01
IRAK2 mediated activation of TAK1 complex 10 1.62e-01 2.55e-01 2.49e-01
TCR signaling 122 1.65e-01 7.28e-02 2.53e-01
Signaling by FGFR2 60 1.65e-01 1.04e-01 2.54e-01
RNA Polymerase III Chain Elongation 18 1.66e-01 -1.89e-01 2.54e-01
Metabolic disorders of biological oxidation enzymes 26 1.68e-01 1.56e-01 2.58e-01
Activation of NMDA receptors and postsynaptic events 58 1.69e-01 1.04e-01 2.58e-01
G alpha (s) signalling events 143 1.69e-01 6.66e-02 2.59e-01
Signaling by ERBB2 TMD/JMD mutants 17 1.72e-01 1.91e-01 2.62e-01
Tryptophan catabolism 12 1.75e-01 2.26e-01 2.67e-01
PKA-mediated phosphorylation of CREB 17 1.80e-01 1.88e-01 2.74e-01
Transcriptional Regulation by TP53 352 1.82e-01 4.14e-02 2.77e-01
Signaling by FGFR 69 1.85e-01 9.23e-02 2.81e-01
RUNX3 regulates NOTCH signaling 14 1.85e-01 2.05e-01 2.81e-01
RNA Polymerase I Transcription Termination 30 1.85e-01 -1.40e-01 2.81e-01
ABC transporters in lipid homeostasis 14 1.86e-01 -2.04e-01 2.81e-01
HS-GAG biosynthesis 20 1.88e-01 1.70e-01 2.85e-01
Abortive elongation of HIV-1 transcript in the absence of Tat 23 1.92e-01 1.57e-01 2.91e-01
Meiotic recombination 38 1.94e-01 1.22e-01 2.92e-01
Plasma lipoprotein assembly 10 1.97e-01 2.36e-01 2.96e-01
Biosynthesis of DHA-derived SPMs 14 1.97e-01 1.99e-01 2.97e-01
Signaling by PDGFR in disease 19 2.02e-01 1.69e-01 3.04e-01
Translation of structural proteins 28 2.02e-01 1.39e-01 3.04e-01
Glutamate binding, activation of AMPA receptors and synaptic plasticity 20 2.05e-01 1.64e-01 3.07e-01
Trafficking of AMPA receptors 20 2.05e-01 1.64e-01 3.07e-01
Purine salvage 12 2.06e-01 2.11e-01 3.08e-01
RNA Pol II CTD phosphorylation and interaction with CE 27 2.08e-01 1.40e-01 3.11e-01
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 27 2.08e-01 1.40e-01 3.11e-01
Formation of the Early Elongation Complex 33 2.09e-01 1.26e-01 3.11e-01
Formation of the HIV-1 Early Elongation Complex 33 2.09e-01 1.26e-01 3.11e-01
Deadenylation of mRNA 22 2.09e-01 1.55e-01 3.11e-01
Adenylate cyclase inhibitory pathway 11 2.10e-01 2.19e-01 3.12e-01
Regulation of MECP2 expression and activity 28 2.10e-01 1.37e-01 3.12e-01
Recruitment of NuMA to mitotic centrosomes 80 2.10e-01 -8.10e-02 3.12e-01
Cobalamin (Cbl, vitamin B12) transport and metabolism 17 2.11e-01 -1.75e-01 3.13e-01
Late Phase of HIV Life Cycle 131 2.13e-01 6.30e-02 3.16e-01
Negative regulation of NMDA receptor-mediated neuronal transmission 14 2.14e-01 -1.92e-01 3.17e-01
Downstream TCR signaling 101 2.16e-01 7.12e-02 3.20e-01
Anchoring of the basal body to the plasma membrane 97 2.17e-01 -7.26e-02 3.20e-01
Heparan sulfate/heparin (HS-GAG) metabolism 37 2.18e-01 1.17e-01 3.22e-01
Transcriptional activation of mitochondrial biogenesis 51 2.20e-01 9.92e-02 3.24e-01
Synthesis of bile acids and bile salts 24 2.21e-01 1.44e-01 3.25e-01
Dectin-2 family 19 2.22e-01 1.62e-01 3.26e-01
Adrenaline,noradrenaline inhibits insulin secretion 24 2.22e-01 1.44e-01 3.26e-01
Regulation of HSF1-mediated heat shock response 79 2.22e-01 -7.94e-02 3.26e-01
VEGFR2 mediated cell proliferation 18 2.23e-01 1.66e-01 3.27e-01
FCERI mediated Ca+2 mobilization 89 2.26e-01 -7.42e-02 3.31e-01
Cyclin A/B1/B2 associated events during G2/M transition 25 2.27e-01 1.40e-01 3.32e-01
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 18 2.27e-01 1.64e-01 3.32e-01
Transcription of the HIV genome 67 2.28e-01 8.51e-02 3.33e-01
Centrosome maturation 81 2.32e-01 -7.69e-02 3.36e-01
Recruitment of mitotic centrosome proteins and complexes 81 2.32e-01 -7.69e-02 3.36e-01
Formation of HIV-1 elongation complex containing HIV-1 Tat 42 2.32e-01 1.07e-01 3.36e-01
HIV Transcription Elongation 42 2.32e-01 1.07e-01 3.36e-01
Tat-mediated elongation of the HIV-1 transcript 42 2.32e-01 1.07e-01 3.36e-01
ECM proteoglycans 35 2.32e-01 1.17e-01 3.36e-01
Synthesis of PIPs at the late endosome membrane 11 2.32e-01 2.08e-01 3.36e-01
FCGR3A-mediated IL10 synthesis 99 2.34e-01 -6.92e-02 3.38e-01
Chromatin modifying enzymes 218 2.34e-01 4.67e-02 3.38e-01
Chromatin organization 218 2.34e-01 4.67e-02 3.38e-01
Post NMDA receptor activation events 48 2.36e-01 9.88e-02 3.41e-01
Non-integrin membrane-ECM interactions 37 2.38e-01 1.12e-01 3.42e-01
Formation of HIV elongation complex in the absence of HIV Tat 44 2.38e-01 1.03e-01 3.42e-01
DAG and IP3 signaling 33 2.39e-01 1.18e-01 3.43e-01
Unblocking of NMDA receptors, glutamate binding and activation 12 2.42e-01 -1.95e-01 3.47e-01
SUMOylation 166 2.45e-01 -5.23e-02 3.52e-01
Cytosolic iron-sulfur cluster assembly 13 2.46e-01 -1.86e-01 3.53e-01
Nuclear Envelope Breakdown 53 2.46e-01 -9.20e-02 3.53e-01
RAF-independent MAPK1/3 activation 21 2.47e-01 1.46e-01 3.53e-01
Signaling by NTRK2 (TRKB) 20 2.47e-01 1.50e-01 3.53e-01
RNA Polymerase III Transcription Initiation From Type 3 Promoter 28 2.48e-01 -1.26e-01 3.54e-01
HSF1-dependent transactivation 29 2.49e-01 1.24e-01 3.54e-01
Other semaphorin interactions 16 2.52e-01 1.65e-01 3.59e-01
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 38 2.54e-01 -1.07e-01 3.61e-01
Miscellaneous transport and binding events 20 2.54e-01 1.47e-01 3.61e-01
Mitotic Prometaphase 185 2.57e-01 -4.83e-02 3.65e-01
Cellular response to heat stress 93 2.59e-01 -6.78e-02 3.67e-01
Assembly of active LPL and LIPC lipase complexes 10 2.60e-01 2.06e-01 3.68e-01
ADORA2B mediated anti-inflammatory cytokines production 73 2.62e-01 7.60e-02 3.70e-01
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 104 2.63e-01 -6.36e-02 3.71e-01
A tetrasaccharide linker sequence is required for GAG synthesis 17 2.65e-01 -1.56e-01 3.74e-01
Regulation of IFNA signaling 12 2.67e-01 1.85e-01 3.77e-01
Signaling by NOTCH2 30 2.68e-01 1.17e-01 3.77e-01
G2/M Checkpoints 140 2.68e-01 5.42e-02 3.77e-01
Regulation of localization of FOXO transcription factors 12 2.71e-01 1.84e-01 3.81e-01
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 46 2.74e-01 9.31e-02 3.85e-01
Disorders of developmental biology 12 2.76e-01 1.82e-01 3.87e-01
Loss of function of MECP2 in Rett syndrome 12 2.76e-01 1.82e-01 3.87e-01
Pervasive developmental disorders 12 2.76e-01 1.82e-01 3.87e-01
Cytosolic tRNA aminoacylation 24 2.78e-01 -1.28e-01 3.89e-01
FRS-mediated FGFR3 signaling 11 2.78e-01 1.89e-01 3.89e-01
Synthesis of PE 12 2.79e-01 -1.81e-01 3.89e-01
Antigen Presentation: Folding, assembly and peptide loading of class I MHC 25 2.80e-01 1.25e-01 3.90e-01
Amino acid transport across the plasma membrane 24 2.81e-01 1.27e-01 3.91e-01
Blood group systems biosynthesis 17 2.81e-01 1.51e-01 3.91e-01
Cytosolic sulfonation of small molecules 19 2.81e-01 1.43e-01 3.91e-01
DNA Damage Bypass 47 2.82e-01 -9.07e-02 3.92e-01
Regulation of TNFR1 signaling 32 2.84e-01 -1.09e-01 3.94e-01
Cohesin Loading onto Chromatin 10 2.84e-01 1.96e-01 3.94e-01
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) 12 2.87e-01 1.77e-01 3.98e-01
Metal ion SLC transporters 21 2.88e-01 1.34e-01 3.99e-01
Olfactory Signaling Pathway 60 2.89e-01 7.91e-02 4.00e-01
Keratan sulfate/keratin metabolism 27 2.91e-01 1.17e-01 4.02e-01
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 17 2.93e-01 -1.47e-01 4.04e-01
Signaling by FGFR2 IIIa TM 18 2.95e-01 1.43e-01 4.06e-01
Aflatoxin activation and detoxification 14 2.99e-01 1.60e-01 4.10e-01
Metabolism of amine-derived hormones 10 2.99e-01 -1.90e-01 4.10e-01
Diseases of metabolism 191 2.99e-01 4.36e-02 4.10e-01
Telomere Extension By Telomerase 23 3.01e-01 -1.24e-01 4.14e-01
NRAGE signals death through JNK 53 3.03e-01 8.19e-02 4.14e-01
Signaling by ERBB2 ECD mutants 15 3.03e-01 1.54e-01 4.14e-01
Defects in cobalamin (B12) metabolism 13 3.03e-01 -1.65e-01 4.15e-01
Transcriptional regulation by small RNAs 63 3.04e-01 7.49e-02 4.15e-01
Vitamin B5 (pantothenate) metabolism 17 3.05e-01 1.44e-01 4.16e-01
VEGFR2 mediated vascular permeability 27 3.08e-01 1.13e-01 4.20e-01
CD28 dependent Vav1 pathway 12 3.08e-01 1.70e-01 4.20e-01
Acyl chain remodelling of PG 11 3.12e-01 1.76e-01 4.24e-01
RNA Polymerase III Abortive And Retractive Initiation 41 3.15e-01 -9.06e-02 4.28e-01
RNA Polymerase III Transcription 41 3.15e-01 -9.06e-02 4.28e-01
Formation of the ternary complex, and subsequently, the 43S complex 51 3.16e-01 -8.11e-02 4.29e-01
Interleukin-2 family signaling 38 3.19e-01 9.35e-02 4.32e-01
IGF1R signaling cascade 36 3.24e-01 9.49e-02 4.39e-01
HS-GAG degradation 16 3.25e-01 1.42e-01 4.39e-01
MET activates PTK2 signaling 15 3.25e-01 1.47e-01 4.39e-01
NCAM signaling for neurite out-growth 43 3.26e-01 -8.66e-02 4.39e-01
Positive epigenetic regulation of rRNA expression 62 3.26e-01 7.21e-02 4.39e-01
Transcriptional regulation of pluripotent stem cells 20 3.26e-01 1.27e-01 4.39e-01
Metabolism of folate and pterines 16 3.26e-01 1.42e-01 4.40e-01
Cytochrome P450 - arranged by substrate type 36 3.28e-01 9.43e-02 4.41e-01
E2F mediated regulation of DNA replication 22 3.32e-01 -1.20e-01 4.46e-01
RAS processing 19 3.32e-01 1.28e-01 4.46e-01
SUMO E3 ligases SUMOylate target proteins 160 3.33e-01 -4.44e-02 4.46e-01
Polo-like kinase mediated events 16 3.33e-01 1.40e-01 4.46e-01
Early Phase of HIV Life Cycle 14 3.34e-01 -1.49e-01 4.47e-01
NOTCH2 Activation and Transmission of Signal to the Nucleus 20 3.35e-01 1.25e-01 4.48e-01
Nonhomologous End-Joining (NHEJ) 42 3.36e-01 8.58e-02 4.49e-01
Repression of WNT target genes 14 3.36e-01 -1.48e-01 4.49e-01
Inositol phosphate metabolism 42 3.38e-01 8.54e-02 4.51e-01
Platelet calcium homeostasis 22 3.38e-01 1.18e-01 4.51e-01
HIV Life Cycle 144 3.39e-01 4.61e-02 4.51e-01
DNA Double Strand Break Response 47 3.40e-01 8.05e-02 4.52e-01
FRS-mediated FGFR4 signaling 12 3.40e-01 1.59e-01 4.52e-01
Nef mediated downregulation of MHC class I complex cell surface expression 10 3.41e-01 1.74e-01 4.52e-01
Scavenging of heme from plasma 71 3.41e-01 -6.53e-02 4.52e-01
mitochondrial fatty acid beta-oxidation of saturated fatty acids 11 3.45e-01 1.64e-01 4.57e-01
Downstream signaling of activated FGFR3 16 3.48e-01 1.35e-01 4.61e-01
Class I peroxisomal membrane protein import 20 3.49e-01 -1.21e-01 4.61e-01
Activation of RAC1 11 3.49e-01 1.63e-01 4.61e-01
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 84 3.51e-01 -5.89e-02 4.63e-01
FRS-mediated FGFR1 signaling 14 3.52e-01 1.44e-01 4.63e-01
Regulation of beta-cell development 19 3.52e-01 1.23e-01 4.63e-01
Downregulation of ERBB2:ERBB3 signaling 12 3.53e-01 1.55e-01 4.64e-01
The phototransduction cascade 26 3.54e-01 -1.05e-01 4.65e-01
Regulation of expression of SLITs and ROBOs 161 3.55e-01 -4.22e-02 4.66e-01
Maturation of nucleoprotein 10 3.55e-01 -1.69e-01 4.66e-01
Translesion Synthesis by POLH 18 3.56e-01 -1.26e-01 4.66e-01
Degradation of cysteine and homocysteine 12 3.57e-01 1.54e-01 4.67e-01
SUMOylation of transcription factors 16 3.57e-01 1.33e-01 4.67e-01
PKMTs methylate histone lysines 45 3.58e-01 -7.92e-02 4.68e-01
DDX58/IFIH1-mediated induction of interferon-alpha/beta 63 3.59e-01 6.68e-02 4.69e-01
Ephrin signaling 18 3.62e-01 1.24e-01 4.72e-01
Molecules associated with elastic fibres 22 3.63e-01 1.12e-01 4.73e-01
Processing of Capped Intron-Containing Pre-mRNA 238 3.66e-01 -3.40e-02 4.76e-01
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 36 3.69e-01 8.65e-02 4.80e-01
Regulation of TP53 Activity through Methylation 19 3.70e-01 -1.19e-01 4.81e-01
Incretin synthesis, secretion, and inactivation 10 3.71e-01 1.63e-01 4.81e-01
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) 10 3.71e-01 1.63e-01 4.81e-01
Interconversion of nucleotide di- and triphosphates 27 3.75e-01 9.87e-02 4.86e-01
Protein methylation 15 3.83e-01 1.30e-01 4.95e-01
Chondroitin sulfate/dermatan sulfate metabolism 38 3.91e-01 8.04e-02 5.06e-01
Zinc transporters 14 3.93e-01 1.32e-01 5.08e-01
NOTCH2 intracellular domain regulates transcription 11 3.95e-01 1.48e-01 5.10e-01
IRS-related events triggered by IGF1R 35 3.95e-01 8.30e-02 5.10e-01
mRNA Capping 29 3.97e-01 9.08e-02 5.12e-01
Downstream signaling of activated FGFR4 17 4.02e-01 1.17e-01 5.17e-01
Long-term potentiation 14 4.04e-01 -1.29e-01 5.19e-01
Interleukin receptor SHC signaling 23 4.04e-01 1.00e-01 5.19e-01
Base Excision Repair 58 4.05e-01 -6.32e-02 5.19e-01
Mitochondrial calcium ion transport 22 4.05e-01 1.03e-01 5.19e-01
Transport of inorganic cations/anions and amino acids/oligopeptides 80 4.08e-01 5.35e-02 5.22e-01
Diseases associated with glycosaminoglycan metabolism 26 4.08e-01 9.38e-02 5.22e-01
Regulation of TP53 Activity through Association with Co-factors 12 4.09e-01 -1.38e-01 5.23e-01
SLBP independent Processing of Histone Pre-mRNAs 10 4.10e-01 -1.51e-01 5.23e-01
Adherens junctions interactions 19 4.11e-01 1.09e-01 5.25e-01
HSF1 activation 26 4.12e-01 9.30e-02 5.25e-01
Formation of Senescence-Associated Heterochromatin Foci (SAHF) 13 4.21e-01 1.29e-01 5.36e-01
Activation of BH3-only proteins 30 4.22e-01 8.48e-02 5.37e-01
Post-translational modification: synthesis of GPI-anchored proteins 57 4.25e-01 6.11e-02 5.40e-01
Assembly and cell surface presentation of NMDA receptors 18 4.29e-01 -1.08e-01 5.45e-01
Cholesterol biosynthesis 24 4.30e-01 9.30e-02 5.45e-01
Interleukin-20 family signaling 17 4.30e-01 1.11e-01 5.45e-01
Neurotransmitter release cycle 39 4.31e-01 7.29e-02 5.45e-01
Cell-cell junction organization 39 4.31e-01 7.29e-02 5.45e-01
Signaling by WNT in cancer 30 4.31e-01 8.30e-02 5.45e-01
Loss of Nlp from mitotic centrosomes 69 4.32e-01 -5.47e-02 5.45e-01
Loss of proteins required for interphase microtubule organization from the centrosome 69 4.32e-01 -5.47e-02 5.45e-01
Cyclin D associated events in G1 47 4.33e-01 6.61e-02 5.46e-01
G1 Phase 47 4.33e-01 6.61e-02 5.46e-01
RUNX2 regulates osteoblast differentiation 19 4.36e-01 -1.03e-01 5.48e-01
Class A/1 (Rhodopsin-like receptors) 169 4.36e-01 3.47e-02 5.48e-01
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 37 4.36e-01 7.39e-02 5.48e-01
Signaling by Activin 10 4.40e-01 -1.41e-01 5.52e-01
G1/S-Specific Transcription 29 4.40e-01 -8.28e-02 5.52e-01
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 23 4.43e-01 9.25e-02 5.54e-01
Constitutive Signaling by Aberrant PI3K in Cancer 54 4.44e-01 6.02e-02 5.56e-01
S Phase 161 4.47e-01 -3.48e-02 5.58e-01
Cell Cycle, Mitotic 503 4.49e-01 1.97e-02 5.61e-01
Ovarian tumor domain proteases 37 4.53e-01 7.13e-02 5.65e-01
Folding of actin by CCT/TriC 10 4.53e-01 1.37e-01 5.65e-01
Regulation of pyruvate dehydrogenase (PDH) complex 15 4.56e-01 1.11e-01 5.68e-01
Synthesis of IP3 and IP4 in the cytosol 22 4.56e-01 9.17e-02 5.68e-01
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation 10 4.57e-01 1.36e-01 5.69e-01
SUMOylation of transcription cofactors 44 4.59e-01 6.45e-02 5.70e-01
Downstream signaling of activated FGFR1 20 4.62e-01 9.49e-02 5.74e-01
Phase 4 - resting membrane potential 10 4.63e-01 1.34e-01 5.75e-01
Role of LAT2/NTAL/LAB on calcium mobilization 74 4.69e-01 -4.87e-02 5.81e-01
Ras activation upon Ca2+ influx through NMDA receptor 15 4.70e-01 -1.08e-01 5.81e-01
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 43 4.72e-01 6.34e-02 5.84e-01
TP53 Regulates Transcription of Cell Cycle Genes 48 4.74e-01 5.97e-02 5.86e-01
Metabolism of vitamins and cofactors 156 4.76e-01 3.31e-02 5.87e-01
The canonical retinoid cycle in rods (twilight vision) 10 4.76e-01 1.30e-01 5.87e-01
APC/C:Cdc20 mediated degradation of Cyclin B 24 4.76e-01 8.40e-02 5.87e-01
RNA Polymerase I Promoter Clearance 66 4.78e-01 5.05e-02 5.88e-01
RNA Polymerase I Transcription 66 4.78e-01 5.05e-02 5.88e-01
MECP2 regulates neuronal receptors and channels 13 4.78e-01 1.14e-01 5.88e-01
Mitotic G1 phase and G1/S transition 148 4.86e-01 3.32e-02 5.95e-01
TNFs bind their physiological receptors 25 4.86e-01 -8.06e-02 5.95e-01
O-linked glycosylation 84 4.86e-01 -4.40e-02 5.95e-01
Global Genome Nucleotide Excision Repair (GG-NER) 84 4.86e-01 -4.40e-02 5.95e-01
Cellular hexose transport 15 4.86e-01 -1.04e-01 5.95e-01
DNA Replication Pre-Initiation 83 4.87e-01 4.42e-02 5.95e-01
Telomere Maintenance 80 4.88e-01 -4.48e-02 5.96e-01
Downregulation of SMAD2/3:SMAD4 transcriptional activity 23 4.90e-01 8.31e-02 5.98e-01
Reproduction 80 4.93e-01 4.43e-02 6.01e-01
RUNX3 regulates p14-ARF 10 4.97e-01 1.24e-01 6.05e-01
Synthesis of DNA 119 5.06e-01 -3.53e-02 6.16e-01
IRS-mediated signalling 34 5.09e-01 6.55e-02 6.18e-01
Regulation of KIT signaling 15 5.12e-01 9.79e-02 6.21e-01
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 25 5.13e-01 7.56e-02 6.23e-01
SHC-mediated cascade:FGFR4 10 5.17e-01 1.18e-01 6.27e-01
SHC-mediated cascade:FGFR1 12 5.19e-01 1.07e-01 6.29e-01
TP53 Regulates Transcription of DNA Repair Genes 61 5.20e-01 -4.76e-02 6.29e-01
Inactivation, recovery and regulation of the phototransduction cascade 25 5.22e-01 -7.40e-02 6.31e-01
Regulation of FOXO transcriptional activity by acetylation 10 5.27e-01 1.16e-01 6.37e-01
Processing of Intronless Pre-mRNAs 19 5.28e-01 -8.37e-02 6.37e-01
Phase 2 - plateau phase 17 5.30e-01 -8.80e-02 6.39e-01
Nicotinamide salvaging 14 5.31e-01 -9.67e-02 6.40e-01
Metabolism of water-soluble vitamins and cofactors 110 5.37e-01 -3.41e-02 6.46e-01
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 91 5.38e-01 -3.74e-02 6.46e-01
Amplification of signal from the kinetochores 91 5.38e-01 -3.74e-02 6.46e-01
Transcriptional Regulation by VENTX 38 5.38e-01 -5.77e-02 6.46e-01
Interleukin-7 signaling 21 5.38e-01 7.76e-02 6.46e-01
Nephrin family interactions 18 5.40e-01 -8.33e-02 6.48e-01
Purine catabolism 16 5.42e-01 8.80e-02 6.49e-01
Caspase-mediated cleavage of cytoskeletal proteins 12 5.47e-01 1.01e-01 6.54e-01
STING mediated induction of host immune responses 15 5.48e-01 8.96e-02 6.55e-01
N-Glycan antennae elongation 13 5.54e-01 -9.48e-02 6.61e-01
MicroRNA (miRNA) biogenesis 24 5.54e-01 6.97e-02 6.61e-01
Acetylcholine Neurotransmitter Release Cycle 11 5.55e-01 -1.03e-01 6.61e-01
mRNA Splicing - Minor Pathway 52 5.56e-01 4.72e-02 6.63e-01
Acyl chain remodelling of PS 14 5.59e-01 9.02e-02 6.65e-01
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 17 5.60e-01 -8.16e-02 6.66e-01
Glutamate and glutamine metabolism 12 5.61e-01 -9.69e-02 6.67e-01
Cargo trafficking to the periciliary membrane 47 5.63e-01 4.88e-02 6.68e-01
PI-3K cascade:FGFR1 12 5.63e-01 9.63e-02 6.68e-01
Endosomal/Vacuolar pathway 12 5.63e-01 -9.63e-02 6.68e-01
PI-3K cascade:FGFR4 10 5.65e-01 1.05e-01 6.69e-01
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 17 5.71e-01 -7.93e-02 6.76e-01
Condensation of Prometaphase Chromosomes 11 5.73e-01 9.81e-02 6.78e-01
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 19 5.78e-01 -7.36e-02 6.83e-01
Mitotic Spindle Checkpoint 108 5.80e-01 -3.08e-02 6.84e-01
FGFR2 alternative splicing 25 5.82e-01 6.37e-02 6.86e-01
TRP channels 19 5.83e-01 -7.28e-02 6.87e-01
PERK regulates gene expression 31 5.86e-01 5.66e-02 6.89e-01
Synthesis of glycosylphosphatidylinositol (GPI) 17 5.89e-01 -7.56e-02 6.93e-01
PI3K Cascade 30 5.90e-01 5.69e-02 6.93e-01
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 27 5.92e-01 5.96e-02 6.95e-01
GPCR ligand binding 235 5.92e-01 2.03e-02 6.95e-01
Meiosis 68 5.93e-01 3.75e-02 6.95e-01
Sema3A PAK dependent Axon repulsion 16 5.96e-01 7.66e-02 6.97e-01
Regulation of RUNX1 Expression and Activity 18 5.97e-01 -7.20e-02 6.98e-01
AURKA Activation by TPX2 72 5.98e-01 -3.60e-02 6.99e-01
Basigin interactions 23 6.01e-01 6.31e-02 7.01e-01
Gamma carboxylation, hypusine formation and arylsulfatase activation 34 6.03e-01 5.15e-02 7.04e-01
Synthesis of IP2, IP, and Ins in the cytosol 13 6.04e-01 8.31e-02 7.04e-01
Lysine catabolism 11 6.10e-01 8.87e-02 7.10e-01
WNT ligand biogenesis and trafficking 21 6.10e-01 6.42e-02 7.10e-01
Elevation of cytosolic Ca2+ levels 13 6.11e-01 8.15e-02 7.10e-01
Association of TriC/CCT with target proteins during biosynthesis 37 6.11e-01 4.83e-02 7.10e-01
Ion transport by P-type ATPases 43 6.12e-01 4.47e-02 7.11e-01
Signaling by NTRK3 (TRKC) 16 6.13e-01 7.29e-02 7.12e-01
CD28 co-stimulation 33 6.17e-01 -5.03e-02 7.15e-01
Fertilization 12 6.19e-01 8.29e-02 7.16e-01
Cytosolic sensors of pathogen-associated DNA 62 6.19e-01 3.65e-02 7.16e-01
Mitochondrial protein import 64 6.19e-01 3.59e-02 7.16e-01
Neurexins and neuroligins 37 6.21e-01 -4.70e-02 7.17e-01
RIPK1-mediated regulated necrosis 16 6.23e-01 7.11e-02 7.18e-01
Regulated Necrosis 16 6.23e-01 7.11e-02 7.18e-01
mRNA 3'-end processing 56 6.29e-01 -3.73e-02 7.25e-01
Interleukin-37 signaling 19 6.31e-01 6.36e-02 7.26e-01
Prolactin receptor signaling 11 6.33e-01 8.30e-02 7.29e-01
Netrin-1 signaling 40 6.38e-01 4.30e-02 7.33e-01
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 11 6.43e-01 -8.08e-02 7.38e-01
Cell Cycle Checkpoints 260 6.48e-01 1.65e-02 7.43e-01
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) 10 6.50e-01 -8.28e-02 7.45e-01
TICAM1-dependent activation of IRF3/IRF7 12 6.52e-01 7.51e-02 7.47e-01
TP53 Regulates Transcription of Death Receptors and Ligands 12 6.55e-01 7.46e-02 7.49e-01
Formation of Incision Complex in GG-NER 43 6.56e-01 3.93e-02 7.50e-01
Branched-chain amino acid catabolism 21 6.58e-01 -5.57e-02 7.52e-01
TRAF6 mediated IRF7 activation 15 6.59e-01 6.59e-02 7.52e-01
Processing of DNA double-strand break ends 71 6.59e-01 -3.03e-02 7.52e-01
Processing of Capped Intronless Pre-mRNA 28 6.63e-01 -4.76e-02 7.55e-01
DNA Replication 126 6.64e-01 -2.24e-02 7.56e-01
Visual phototransduction 60 6.65e-01 3.23e-02 7.57e-01
Competing endogenous RNAs (ceRNAs) regulate PTEN translation 11 6.66e-01 -7.51e-02 7.57e-01
NOTCH4 Intracellular Domain Regulates Transcription 18 6.67e-01 5.87e-02 7.57e-01
Signaling by FGFR2 in disease 32 6.67e-01 4.39e-02 7.57e-01
Diseases associated with N-glycosylation of proteins 17 6.85e-01 5.69e-02 7.76e-01
G2/M DNA damage checkpoint 68 6.86e-01 -2.84e-02 7.77e-01
Other interleukin signaling 18 6.95e-01 5.34e-02 7.85e-01
RNA Polymerase II Transcription Termination 65 6.95e-01 -2.81e-02 7.85e-01
Gap-filling DNA repair synthesis and ligation in TC-NER 64 6.95e-01 -2.84e-02 7.85e-01
Establishment of Sister Chromatid Cohesion 11 6.97e-01 6.78e-02 7.87e-01
DAP12 signaling 28 6.98e-01 4.23e-02 7.88e-01
Xenobiotics 12 7.03e-01 -6.35e-02 7.93e-01
Signaling by FGFR4 in disease 11 7.05e-01 6.59e-02 7.94e-01
RHO GTPases Activate Formins 117 7.09e-01 2.00e-02 7.97e-01
Organelle biogenesis and maintenance 269 7.09e-01 -1.32e-02 7.97e-01
Binding and Uptake of Ligands by Scavenger Receptors 93 7.09e-01 2.24e-02 7.97e-01
Deactivation of the beta-catenin transactivating complex 36 7.10e-01 3.58e-02 7.97e-01
TP53 Regulates Transcription of Caspase Activators and Caspases 12 7.13e-01 -6.13e-02 8.00e-01
Regulation of Complement cascade 95 7.15e-01 -2.17e-02 8.01e-01
Complement cascade 99 7.15e-01 -2.12e-02 8.01e-01
Cell Cycle 625 7.16e-01 -8.52e-03 8.01e-01
Synthesis, secretion, and deacylation of Ghrelin 11 7.16e-01 -6.33e-02 8.01e-01
Synthesis of PIPs at the Golgi membrane 16 7.21e-01 5.16e-02 8.05e-01
Phosphorylation of the APC/C 20 7.21e-01 4.61e-02 8.05e-01
Pregnenolone biosynthesis 10 7.23e-01 6.47e-02 8.06e-01
Regulation of PTEN mRNA translation 13 7.23e-01 -5.67e-02 8.06e-01
Receptor-type tyrosine-protein phosphatases 12 7.24e-01 5.89e-02 8.06e-01
RNA Polymerase III Transcription Termination 23 7.25e-01 -4.24e-02 8.06e-01
Processing of SMDT1 15 7.30e-01 5.14e-02 8.12e-01
Glucagon-type ligand receptors 20 7.32e-01 4.42e-02 8.13e-01
Processing and activation of SUMO 10 7.35e-01 6.17e-02 8.16e-01
Aberrant regulation of mitotic cell cycle due to RB1 defects 36 7.45e-01 -3.13e-02 8.25e-01
Diseases of mitotic cell cycle 36 7.45e-01 -3.13e-02 8.25e-01
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20 7.45e-01 -4.20e-02 8.25e-01
Eicosanoid ligand-binding receptors 13 7.48e-01 -5.14e-02 8.28e-01
PI-3K cascade:FGFR2 12 7.50e-01 -5.32e-02 8.28e-01
TNFR1-induced NFkappaB signaling pathway 25 7.50e-01 -3.68e-02 8.28e-01
EML4 and NUDC in mitotic spindle formation 95 7.52e-01 -1.87e-02 8.30e-01
Sulfur amino acid metabolism 22 7.53e-01 3.88e-02 8.30e-01
Signaling by KIT in disease 20 7.56e-01 -4.01e-02 8.33e-01
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants 20 7.56e-01 -4.01e-02 8.33e-01
Glutamate Neurotransmitter Release Cycle 20 7.57e-01 -4.00e-02 8.33e-01
Ribosomal scanning and start codon recognition 58 7.59e-01 -2.33e-02 8.34e-01
Signaling by NODAL 13 7.62e-01 -4.86e-02 8.37e-01
TRAF3-dependent IRF activation pathway 13 7.63e-01 4.82e-02 8.38e-01
Signaling by Retinoic Acid 31 7.73e-01 3.00e-02 8.47e-01
Mitochondrial Fatty Acid Beta-Oxidation 36 7.77e-01 2.73e-02 8.52e-01
PIWI-interacting RNA (piRNA) biogenesis 24 7.81e-01 3.28e-02 8.55e-01
Regulation of PLK1 Activity at G2/M Transition 87 7.83e-01 -1.71e-02 8.56e-01
Class B/2 (Secretin family receptors) 56 7.84e-01 2.11e-02 8.57e-01
SUMOylation of DNA methylation proteins 16 7.86e-01 -3.91e-02 8.59e-01
HATs acetylate histones 93 7.88e-01 -1.61e-02 8.60e-01
HCMV Early Events 74 7.91e-01 1.78e-02 8.62e-01
Norepinephrine Neurotransmitter Release Cycle 14 7.92e-01 4.07e-02 8.63e-01
Signaling by ROBO receptors 201 7.93e-01 -1.07e-02 8.63e-01
Epigenetic regulation of gene expression 103 7.96e-01 1.47e-02 8.66e-01
FCERI mediated MAPK activation 90 7.97e-01 1.57e-02 8.66e-01
Voltage gated Potassium channels 25 7.97e-01 2.97e-02 8.66e-01
Deposition of new CENPA-containing nucleosomes at the centromere 40 8.00e-01 2.32e-02 8.67e-01
Nucleosome assembly 40 8.00e-01 2.32e-02 8.67e-01
SHC-mediated cascade:FGFR2 12 8.01e-01 -4.21e-02 8.67e-01
Termination of O-glycan biosynthesis 16 8.02e-01 3.63e-02 8.67e-01
Defective B4GALT7 causes EDS, progeroid type 11 8.02e-01 -4.37e-02 8.67e-01
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12 8.02e-01 4.18e-02 8.67e-01
Lewis blood group biosynthesis 13 8.04e-01 3.97e-02 8.69e-01
Translation initiation complex formation 58 8.09e-01 -1.83e-02 8.74e-01
IL-6-type cytokine receptor ligand interactions 12 8.11e-01 3.98e-02 8.75e-01
Dual incision in TC-NER 65 8.15e-01 -1.67e-02 8.79e-01
CDC6 association with the ORC:origin complex 11 8.20e-01 -3.95e-02 8.83e-01
Interleukin-2 signaling 11 8.25e-01 3.84e-02 8.88e-01
Inactivation of APC/C via direct inhibition of the APC/C complex 21 8.32e-01 -2.68e-02 8.93e-01
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 21 8.32e-01 -2.68e-02 8.93e-01
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects 17 8.34e-01 -2.94e-02 8.94e-01
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) 17 8.34e-01 -2.94e-02 8.94e-01
APC-Cdc20 mediated degradation of Nek2A 26 8.37e-01 2.34e-02 8.96e-01
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 14 8.38e-01 -3.16e-02 8.97e-01
CLEC7A (Dectin-1) induces NFAT activation 11 8.40e-01 -3.52e-02 8.98e-01
N-glycan antennae elongation in the medial/trans-Golgi 21 8.40e-01 -2.54e-02 8.98e-01
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 11 8.42e-01 3.47e-02 9.00e-01
IRF3-mediated induction of type I IFN 12 8.44e-01 -3.29e-02 9.00e-01
Nucleotide-like (purinergic) receptors 13 8.44e-01 3.15e-02 9.00e-01
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion 14 8.45e-01 -3.02e-02 9.01e-01
Cardiac conduction 92 8.48e-01 1.16e-02 9.02e-01
Synthesis of PA 32 8.50e-01 1.94e-02 9.02e-01
Metabolism of amino acids and derivatives 326 8.50e-01 -6.08e-03 9.02e-01
Interaction between L1 and Ankyrins 22 8.50e-01 2.33e-02 9.02e-01
Serotonin Neurotransmitter Release Cycle 15 8.50e-01 2.81e-02 9.02e-01
FGFR2 mutant receptor activation 22 8.51e-01 2.31e-02 9.02e-01
G0 and Early G1 27 8.52e-01 2.08e-02 9.02e-01
GABA synthesis, release, reuptake and degradation 13 8.52e-01 -2.98e-02 9.02e-01
Constitutive Signaling by NOTCH1 HD Domain Mutants 14 8.54e-01 2.85e-02 9.02e-01
Signaling by NOTCH1 HD Domain Mutants in Cancer 14 8.54e-01 2.85e-02 9.02e-01
Vitamin D (calciferol) metabolism 10 8.57e-01 3.29e-02 9.05e-01
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 16 8.58e-01 -2.59e-02 9.05e-01
Activation of SMO 13 8.65e-01 2.73e-02 9.12e-01
EGR2 and SOX10-mediated initiation of Schwann cell myelination 22 8.65e-01 2.10e-02 9.12e-01
Mitochondrial translation termination 91 8.68e-01 -1.01e-02 9.14e-01
KSRP (KHSRP) binds and destabilizes mRNA 17 8.69e-01 -2.32e-02 9.14e-01
RUNX2 regulates bone development 24 8.75e-01 -1.85e-02 9.20e-01
Mitochondrial translation elongation 91 8.78e-01 -9.27e-03 9.23e-01
Signaling by BMP 21 8.81e-01 -1.89e-02 9.25e-01
Nucleotide Excision Repair 110 8.85e-01 -8.00e-03 9.28e-01
Negative regulators of DDX58/IFIH1 signaling 34 8.90e-01 -1.37e-02 9.33e-01
Interleukin-35 Signalling 12 8.91e-01 -2.29e-02 9.33e-01
Regulation of TP53 Expression and Degradation 36 8.93e-01 -1.30e-02 9.34e-01
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14 8.98e-01 1.99e-02 9.38e-01
TNF signaling 42 8.99e-01 1.13e-02 9.38e-01
Regulation of innate immune responses to cytosolic DNA 14 8.99e-01 1.96e-02 9.38e-01
Methylation 12 8.99e-01 -2.11e-02 9.38e-01
Downstream signaling of activated FGFR2 19 9.03e-01 1.62e-02 9.41e-01
Keratan sulfate biosynthesis 22 9.04e-01 -1.49e-02 9.42e-01
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 20 9.08e-01 -1.50e-02 9.44e-01
Aberrant regulation of mitotic exit in cancer due to RB1 defects 20 9.08e-01 1.49e-02 9.44e-01
Signaling by FGFR3 in disease 13 9.08e-01 1.84e-02 9.44e-01
Signaling by FGFR3 point mutants in cancer 13 9.08e-01 1.84e-02 9.44e-01
G1/S Transition 130 9.10e-01 5.77e-03 9.44e-01
Defective B3GALT6 causes EDSP2 and SEMDJL1 11 9.10e-01 -1.97e-02 9.44e-01
Diseases of glycosylation 109 9.12e-01 -6.11e-03 9.46e-01
Deadenylation-dependent mRNA decay 53 9.16e-01 -8.41e-03 9.48e-01
DNA Damage Recognition in GG-NER 38 9.16e-01 -9.86e-03 9.48e-01
CTLA4 inhibitory signaling 21 9.19e-01 -1.29e-02 9.50e-01
CRMPs in Sema3A signaling 14 9.19e-01 -1.56e-02 9.50e-01
FRS-mediated FGFR2 signaling 14 9.20e-01 1.56e-02 9.50e-01
Nicotinate metabolism 25 9.21e-01 -1.15e-02 9.50e-01
Resolution of Sister Chromatid Cohesion 104 9.23e-01 -5.49e-03 9.52e-01
Transcription of E2F targets under negative control by DREAM complex 19 9.26e-01 1.23e-02 9.54e-01
Anti-inflammatory response favouring Leishmania parasite infection 169 9.27e-01 4.07e-03 9.54e-01
Leishmania parasite growth and survival 169 9.27e-01 4.07e-03 9.54e-01
Transcription-Coupled Nucleotide Excision Repair (TC-NER) 78 9.29e-01 -5.87e-03 9.54e-01
Dopamine Neurotransmitter Release Cycle 20 9.29e-01 1.15e-02 9.54e-01
Lysosphingolipid and LPA receptors 11 9.30e-01 -1.52e-02 9.55e-01
AKT phosphorylates targets in the nucleus 10 9.31e-01 -1.58e-02 9.55e-01
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 59 9.33e-01 -6.36e-03 9.56e-01
Regulation of necroptotic cell death 14 9.35e-01 -1.27e-02 9.57e-01
FOXO-mediated transcription of cell cycle genes 15 9.36e-01 1.19e-02 9.58e-01
RMTs methylate histone arginines 37 9.37e-01 7.53e-03 9.58e-01
Mitochondrial translation 97 9.40e-01 4.40e-03 9.61e-01
Mitochondrial translation initiation 91 9.42e-01 -4.45e-03 9.61e-01
Defective EXT1 causes exostoses 1, TRPS2 and CHDS 10 9.44e-01 1.29e-02 9.62e-01
Defective EXT2 causes exostoses 2 10 9.44e-01 1.29e-02 9.62e-01
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 31 9.50e-01 6.49e-03 9.67e-01
Regulation of TP53 Degradation 35 9.51e-01 6.03e-03 9.67e-01
SLC transporter disorders 77 9.52e-01 3.97e-03 9.67e-01
mRNA decay by 5' to 3' exoribonuclease 15 9.54e-01 -8.64e-03 9.67e-01
Synthesis of PIPs at the early endosome membrane 16 9.54e-01 -8.25e-03 9.67e-01
CASP8 activity is inhibited 11 9.55e-01 -9.91e-03 9.67e-01
Dimerization of procaspase-8 11 9.55e-01 -9.91e-03 9.67e-01
Regulation by c-FLIP 11 9.55e-01 -9.91e-03 9.67e-01
Regulation of FZD by ubiquitination 15 9.56e-01 -8.14e-03 9.68e-01
Tight junction interactions 18 9.57e-01 7.28e-03 9.68e-01
mRNA Splicing - Major Pathway 179 9.58e-01 -2.29e-03 9.68e-01
Collagen chain trimerization 27 9.60e-01 5.54e-03 9.70e-01
PECAM1 interactions 12 9.62e-01 -7.90e-03 9.71e-01
Kinesins 39 9.64e-01 4.16e-03 9.73e-01
Defective B3GAT3 causes JDSSDHD 11 9.69e-01 -6.88e-03 9.76e-01
Inhibition of replication initiation of damaged DNA by RB1/E2F1 13 9.72e-01 5.64e-03 9.79e-01
ATF4 activates genes in response to endoplasmic reticulum stress 26 9.78e-01 -3.15e-03 9.84e-01
Synaptic adhesion-like molecules 15 9.79e-01 3.89e-03 9.85e-01
mRNA Splicing 187 9.80e-01 1.05e-03 9.85e-01
Protein-protein interactions at synapses 58 9.88e-01 1.16e-03 9.92e-01
DCC mediated attractive signaling 13 9.92e-01 1.61e-03 9.96e-01
Glyoxylate metabolism and glycine degradation 24 9.93e-01 -1.02e-03 9.96e-01
Nuclear Receptor transcription pathway 38 9.93e-01 -7.77e-04 9.96e-01
Gene Silencing by RNA 88 9.96e-01 3.02e-04 9.98e-01
Glutathione synthesis and recycling 10 9.99e-01 -2.37e-04 1.00e+00
Ion homeostasis 41 1.00e+00 -1.34e-05 1.00e+00


Detailed Gene set reports



Neutrophil degranulation

Neutrophil degranulation
736
set Neutrophil degranulation
setSize 458
pANOVA 1.61e-103
s.dist 0.586
p.adjustANOVA 2.2e-100



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A9 9516
S100A12 9515
CTSA 9514
SIRPA 9510
IDH1 9507
RNASE2 9506
MCEMP1 9504
S100A8 9503
CD93 9496
CR1 9486
CREG1 9483
MGST1 9482
BST1 9480
TIMP2 9458
HP 9454
CD36 9444
GCA 9436
PGAM1 9435
SERPINB1 9434
CTSD 9433

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A9 9516
S100A12 9515
CTSA 9514
SIRPA 9510
IDH1 9507
RNASE2 9506
MCEMP1 9504
S100A8 9503
CD93 9496
CR1 9486
CREG1 9483
MGST1 9482
BST1 9480
TIMP2 9458
HP 9454
CD36 9444
GCA 9436
PGAM1 9435
SERPINB1 9434
CTSD 9433
ATP6V0A1 9423
PYGL 9417
LAMTOR1 9411
ITGAM 9398
PKM 9391
DOK3 9388
HK3 9385
SIGLEC9 9383
CKAP4 9370
CTSB 9364
GNS 9360
RAB31 9356
PTAFR 9355
ANPEP 9350
PGM2 9344
QPCT 9327
SDCBP 9311
CDA 9310
GRN 9308
PLD1 9306
QSOX1 9298
FPR1 9295
IMPDH1 9294
CD63 9287
MNDA 9277
VAT1 9276
CYFIP1 9265
LTA4H 9261
PADI2 9257
AGPAT2 9256
ALDOA 9249
MMP8 9232
RAB3D 9207
TOM1 9200
NCSTN 9186
CLEC4D 9185
SLC11A1 9169
SERPINA1 9168
CD55 9145
GPR84 9133
C5AR1 9129
ATP6V0C 9127
CAT 9123
FCN1 9113
FCAR 9111
CRISPLD2 9106
MAPK14 9104
TLR2 9103
TRPM2 9102
CD14 9097
FPR2 9095
VNN1 9092
NFAM1 9086
CYSTM1 9077
OSCAR 9068
GM2A 9059
HBB 9054
MGAM 9050
ATP6V1D 9047
VAPA 9033
CYBB 9031
NEU1 9029
SLC2A3 9021
BRI3 9017
APAF1 9015
GYG1 9013
PRKCD 9008
ALOX5 9001
RETN 8998
CTSZ 8975
S100A11 8946
ITGB2 8942
PRDX6 8937
SERPINB10 8933
RAB10 8926
SELL 8912
CYB5R3 8903
LILRB3 8871
FCGR2A 8845
RAC1 8793
ADAM10 8791
LAMP2 8786
HEXB 8776
ARG1 8759
LGALS3 8752
GSN 8749
RAB7A 8742
TNFAIP6 8738
AMPD3 8732
GLB1 8725
OLFM4 8724
ARPC5 8686
DNAJC5 8679
LRG1 8674
FTL 8665
ALDH3B1 8663
RAB5C 8655
PYCARD 8638
PDXK 8635
DNASE1L1 8632
SNAP23 8628
TOLLIP 8572
GLA 8570
CAPN1 8563
ANXA2 8544
CD68 8533
ASAH1 8529
MMP25 8515
ALAD 8514
DERA 8500
RHOG 8487
PSMB7 8485
FGR 8478
HPSE 8476
CLEC5A 8473
PLAC8 8452
P2RX1 8436
DNAJC3 8435
CEACAM1 8429
PLAUR 8424
PNP 8419
RAB27A 8411
HEBP2 8398
ATP11A 8394
CTSS 8372
TMBIM1 8361
CPPED1 8357
CD44 8333
S100P 8331
RHOA 8319
FUCA2 8304
ACAA1 8292
CAB39 8276
DNAJC13 8263
GMFG 8259
MOSPD2 8252
ARL8A 8249
PRCP 8218
ADGRG3 8204
SIGLEC5 8161
IQGAP1 8152
RAB6A 8148
ATG7 8134
RAB3A 8133
FCER1G 8131
CAP1 8111
HSPA1A 8071
CD33 8069
PLEKHO2 8059
LILRB2 8057
ANO6 8048
TMEM30A 8036
ATP6AP2 8034
C3AR1 8012
ORM1 7971
GAA 7968
COMMD9 7967
PSEN1 7961
COTL1 7933
PGLYRP1 7910
CMTM6 7891
CD53 7884
ACTR2 7870
KCMF1 7869
PECAM1 7855
PSMD6 7846
SIRPB1 7843
TRAPPC1 7806
RAB18 7801
PGRMC1 7795
PTPRJ 7783
LCN2 7755
DBNL 7749
GLIPR1 7739
DOCK2 7725
GUSB 7723
CANT1 7707
NCKAP1L 7673
LAMP1 7631
UNC13D 7607
ACTR10 7605
LAMTOR3 7574
ARSB 7572
LAMTOR2 7567
CRISP3 7552
TYROBP 7539
MAPK1 7493
ROCK1 7489
RNASE3 7471
FOLR3 7451
CFP 7445
MPO 7437
OSTF1 7426
NAPRT 7412
PSMD2 7411
FUCA1 7408
MANBA 7386
ITGAX 7337
VCL 7328
COPB1 7321
ELANE 7320
RAP1A 7305
GDI2 7282
AP2A2 7257
PSMD1 7241
TUBB4B 7240
LYZ 7213
TCIRG1 7188
LAIR1 7184
IGF2R 7149
PSAP 7145
GALNS 7102
RAB14 7095
NBEAL2 7086
SURF4 7058
MVP 7053
TSPAN14 6971
ATP8B4 6970
PAFAH1B2 6942
DYNC1LI1 6941
DDOST 6931
CYBA 6922
METTL7A 6920
ERP44 6905
CSTB 6904
VCP 6886
MAN2B1 6878
CXCR1 6864
CEACAM3 6838
PRTN3 6762
AP1M1 6711
STOM 6704
RAB5B 6690
YPEL5 6684
BPI 6666
CD58 6647
CNN2 6645
DDX3X 6614
IQGAP2 6599
PSMD12 6556
CCT8 6552
HSPA6 6514
AOC1 6509
HSPA1B 6470
ARMC8 6398
SNAP29 6390
CTSH 6360
TICAM2 6335
SRP14 6320
LTF 6306
GPI 6284
NFKB1 6277
ARHGAP9 6256
PSMD11 6231
GGH 6205
C6orf120 6192
TCN1 6182
DEGS1 6169
VPS35L 6118
ITGAV 6106
PTPN6 6096
NDUFC2 6093
ATP11B 6064
DEFA1 6061
DEFA4 6057
TNFRSF1B 6045
PPBP 6042
FABP5 6021
CHIT1 6012
PSMD7 5963
DYNLL1 5952
PSMD13 5948
RNASET2 5922
PDAP1 5908
CPNE3 5872
IST1 5862
CXCR2 5861
CD59 5859
SERPINB6 5854
PGM1 5843
CXCL1 5824
PTX3 5797
BIN2 5745
ADAM8 5634
A1BG 5559
FAF2 5554
STBD1 5544
AZU1 5507
NPC2 5458
XRCC5 5384
NRAS 5363
RAB24 5354
PSMA2 5339
TARM1 5307
DGAT1 5306
SLPI 5298
VAMP8 5218
PTPRN2 5183
ACLY 5159
CTSG 5115
SIGLEC14 5087
CEACAM8 4956
HVCN1 4912
PLAU 4903
FTH1 4902
STING1 4791
CAMP 4785
ABCA13 4768
PSMD3 4618
RAP2C 4599
KRT1 4537
CLEC12A 4535
CEACAM6 4509
DYNLT1 4450
FCGR3B 4313
B4GALT1 4292
GHDC 4158
GOLGA7 4055
CSNK2B 3969
SLC15A4 3724
STK11IP 3586
ARSA 3486
PSMB1 3374
SLCO4C1 3212
RAP1B 3206
RAB4B 3137
SLC44A2 2700
MAGT1 2613
PSMD14 2611
PSMC2 2598
OLR1 2486
CD177 2457
KPNB1 2430
MS4A3 2361
CTSC 2326
MLEC 2322
PTPRC 2240
CST3 2206
SLC2A5 2044
SVIP 2035
CFD 1984
PSMC3 1976
GSDMD 1955
SCAMP1 1868
HGSNAT 1867
NME2 1850
MMP9 1690
HSP90AA1 1326
NHLRC3 1276
HLA-C 1018
APEH 997
MME 916
NFASC 866
FGL2 675
HLA-B 649
RAB44 573
PYGB 492
TMEM179B 449
LRMP 441
ADGRE3 408
TXNDC5 393
EEF2 306
GSTP1 135
FRK -24
KCNAB2 -101
PRDX4 -144
HMGB1 -252
PIGR -487
CHI3L1 -650
RAP2B -771
DIAPH1 -854
COMMD3 -1363
DSP -1812
LRRC7 -1966
ILF2 -1979
UBR4 -2086
CD300A -2133
ORM2 -2564
ADGRE5 -2571
HLA-A -2573
APRT -2766
AGL -3136
PFKL -3277
CPNE1 -3397
ALDOC -3438
SLC27A2 -3831
MIF -3863
HLA-H -3889
STK10 -3898
PA2G4 -3916
XRCC6 -4471
DPP7 -4586
SYNGR1 -4629
AGA -4632
EPX -4838
EEF1A1 -5087
JUP -5353
PSMA5 -6053
RAB9B -6552
CAND1 -6554
PPIA -6766
HSP90AB1 -6863
B2M -6920
PTGES2 -6926
DSC1 -6927
TUBB -6956
HRNR -7349
BST2 -7385
LPCAT1 -7428
PTPRB -7607
DYNC1H1 -7685
HUWE1 -7977
CDK13 -8392
CCT2 -8825
PPIE -9002
CRACR2A -9069
TMEM63A -9137
CEP290 -9182
ENPP4 -9583
IMPDH2 -9916
ORMDL3 -9997
ATAD3B -10079
ACTR1B -10514
TMC6 -10606
DSN1 -10773
ITGAL -10847
HSPA8 -10922
SPTAN1 -11426
FRMPD3 -11469
NIT2 -11695
RAB37 -11793
CLEC4C -11809
HMOX2 -11819
ATP8A1 -11842
TBC1D10C -11861
CD47 -12114
C3 -12262
RHOF -12344


Innate Immune System

Innate Immune System
536
set Innate Immune System
setSize 968
pANOVA 5.83e-84
s.dist 0.367
p.adjustANOVA 3.97e-81



Top enriched genes

Top 20 genes
GeneID Gene Rank
WASF1 9520
S100A9 9516
S100A12 9515
CTSA 9514
SIRPA 9510
IDH1 9507
RNASE2 9506
MCEMP1 9504
S100A8 9503
CD93 9496
CR1 9486
CREG1 9483
MGST1 9482
BST1 9480
TIMP2 9458
HP 9454
CCR2 9449
CD36 9444
GCA 9436
PGAM1 9435

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
WASF1 9520
S100A9 9516
S100A12 9515
CTSA 9514
SIRPA 9510
IDH1 9507
RNASE2 9506
MCEMP1 9504
S100A8 9503
CD93 9496
CR1 9486
CREG1 9483
MGST1 9482
BST1 9480
TIMP2 9458
HP 9454
CCR2 9449
CD36 9444
GCA 9436
PGAM1 9435
SERPINB1 9434
CTSD 9433
PRKACA 9429
ATP6V0A1 9423
PYGL 9417
LAMTOR1 9411
NLRC4 9406
ITGAM 9398
PKM 9391
DOK3 9388
HK3 9385
SIGLEC9 9383
CLU 9371
CKAP4 9370
CTSB 9364
GNS 9360
RASGRP4 9359
RAB31 9356
PTAFR 9355
NKIRAS2 9353
ANPEP 9350
SIGLEC15 9348
PGM2 9344
TLR8 9343
QPCT 9327
FCGR1A 9323
SDCBP 9311
CDA 9310
GRN 9308
PLD1 9306
GRB2 9304
ATP6V1A 9302
QSOX1 9298
FPR1 9295
IMPDH1 9294
CD63 9287
DUSP3 9280
MNDA 9277
VAT1 9276
NCF4 9268
CYFIP1 9265
LTA4H 9261
ARPC1B 9259
PADI2 9257
AGPAT2 9256
ALDOA 9249
ATP6V0D1 9245
MMP8 9232
RAB3D 9207
TLR5 9201
TOM1 9200
NCF2 9190
UBE2D1 9187
NCSTN 9186
CLEC4D 9185
APP 9177
SLC11A1 9169
SERPINA1 9168
SIGLEC16 9164
CD55 9145
GPR84 9133
C5AR1 9129
ATP6V0C 9127
CAT 9123
FCN1 9113
FCAR 9111
IRAK3 9107
CRISPLD2 9106
MAPK14 9104
TLR2 9103
TRPM2 9102
CD14 9097
FPR2 9095
VNN1 9092
NFAM1 9086
CYSTM1 9077
SYK 9076
OSCAR 9068
MAP2K1 9063
GM2A 9059
ATP6V1B2 9057
HBB 9054
MGAM 9050
ATP6V1D 9047
PIK3CB 9038
VAPA 9033
CYBB 9031
NEU1 9029
SLC2A3 9021
BRI3 9017
TLR4 9016
APAF1 9015
GYG1 9013
ACTB 9011
PRKCD 9008
ALOX5 9001
RETN 8998
HCK 8976
CTSZ 8975
MAPK3 8953
S100A11 8946
ITGB2 8942
PRDX6 8937
SERPINB10 8933
TLR1 8932
RAB10 8926
MYO10 8918
SELL 8912
CRK 8906
CYB5R3 8903
NLRP3 8901
ARPC1A 8894
MAP2K6 8887
LILRB3 8871
FCGR2A 8845
TLR6 8840
LAT2 8799
LY96 8795
RAC1 8793
ADAM10 8791
LAMP2 8786
HEXB 8776
ARG1 8759
LGALS3 8752
C1QC 8750
GSN 8749
MAP2K3 8748
ALPK1 8745
RAB7A 8742
TNFAIP6 8738
AMPD3 8732
GLB1 8725
OLFM4 8724
BCL2L1 8700
ARPC5 8686
DNAJC5 8679
LRG1 8674
FTL 8665
ALDH3B1 8663
RAB5C 8655
UBE2D3 8640
PYCARD 8638
PDXK 8635
DNASE1L1 8632
SNAP23 8628
CDC34 8611
MEFV 8605
ATP6V0B 8598
CAPZA2 8597
ATP6V0E1 8596
TOLLIP 8572
GLA 8570
CAPN1 8563
ACTG1 8562
WAS 8560
RNF135 8556
ANXA2 8544
ATP6V1C1 8539
CD68 8533
ASAH1 8529
MMP25 8515
ALAD 8514
DERA 8500
RHOG 8487
PSMB7 8485
FGR 8478
HPSE 8476
CLEC5A 8473
PLAC8 8452
NOD2 8442
P2RX1 8436
DNAJC3 8435
CEACAM1 8429
PLAUR 8424
PNP 8419
RAB27A 8411
PSMD4 8402
HEBP2 8398
ATP11A 8394
MAPKAPK3 8382
CTSS 8372
WASF2 8369
TMBIM1 8361
CPPED1 8357
C1QB 8337
CD44 8333
S100P 8331
CLEC4E 8324
RHOA 8319
PELI2 8314
FUCA2 8304
ACAA1 8292
TXN 8285
ARPC3 8277
CAB39 8276
DNAJC13 8263
CLEC4A 8260
GMFG 8259
MOSPD2 8252
PSME3 8251
ARL8A 8249
PPP2CA 8234
PAK1 8230
TRIM25 8226
PRCP 8218
ADGRG3 8204
C5AR2 8187
CFL1 8186
PAK2 8185
PPP3R1 8175
SIGLEC5 8161
IQGAP1 8152
RAB6A 8148
MYD88 8136
CAPZA1 8135
ATG7 8134
RAB3A 8133
FCER1G 8131
CAP1 8111
PSMB5 8101
GAB2 8099
HSPA1A 8071
CD33 8069
ATP6V1H 8064
PLEKHO2 8059
LILRB2 8057
ANO6 8048
TMEM30A 8036
ATP6V1E1 8035
ATP6AP2 8034
C3AR1 8012
MEF2A 8009
ORM1 7971
GAA 7968
COMMD9 7967
CHUK 7966
PSEN1 7961
COTL1 7933
PGLYRP1 7910
VAV1 7896
CMTM6 7891
CD53 7884
RAF1 7879
ACTR2 7870
KCMF1 7869
PECAM1 7855
PSMD6 7846
SIRPB1 7843
PSTPIP1 7841
NLRX1 7826
ACTR3 7818
LYN 7809
ICAM3 7808
TRAPPC1 7806
RAB18 7801
PGRMC1 7795
PTPRJ 7783
UBA3 7767
CNPY3 7761
PROS1 7758
LCN2 7755
DBNL 7749
GLIPR1 7739
DOCK2 7725
GUSB 7723
PELI3 7716
PPP2CB 7712
CANT1 7707
RPS6KA1 7695
CASP9 7685
NCKAP1L 7673
LY86 7667
LAMP1 7631
PSMD9 7620
UNC13D 7607
ACTR10 7605
LAMTOR3 7574
ARSB 7572
LAMTOR2 7567
POLR2E 7563
CRISP3 7552
TEC 7549
TYROBP 7539
CDC42 7537
ARPC4 7516
TANK 7502
MAPK1 7493
ROCK1 7489
UBE2M 7477
RNASE3 7471
NCKAP1 7462
FOLR3 7451
CFP 7445
MPO 7437
OSTF1 7426
NAPRT 7412
PSMD2 7411
FUCA1 7408
ARPC2 7390
MANBA 7386
PLD3 7364
ITGAX 7337
NCF1 7334
PSMA1 7329
VCL 7328
COPB1 7321
ELANE 7320
DOCK1 7314
RAP1A 7305
GDI2 7282
AP2A2 7257
PSMD1 7241
TUBB4B 7240
LYZ 7213
BTK 7206
TCIRG1 7188
CD300LB 7186
LAIR1 7184
PLD2 7180
PSMB3 7171
IGF2R 7149
PSAP 7145
MAVS 7124
GALNS 7102
PSMA7 7096
RAB14 7095
NBEAL2 7086
ABI1 7082
SURF4 7058
MVP 7053
DNM3 7045
BRK1 7032
PSMC1 7021
TREM1 7009
PPP3CB 7005
TSPAN14 6971
ATP8B4 6970
TAB2 6964
PAFAH1B2 6942
DYNC1LI1 6941
DDOST 6931
CYBA 6922
METTL7A 6920
ERP44 6905
CSTB 6904
VCP 6886
UBE2K 6884
MAN2B1 6878
MAP2K4 6866
CXCR1 6864
CEACAM3 6838
RNASE6 6837
PSMB6 6813
WASF3 6808
NFKBIA 6807
PRTN3 6762
CD300E 6742
CLEC6A 6730
PELI1 6715
AP1M1 6711
STOM 6704
MYO5A 6693
RAB5B 6690
MYH9 6685
YPEL5 6684
BPI 6666
PSMF1 6659
CARD9 6648
CD58 6647
CNN2 6645
UBB 6639
PSMC6 6635
C1QA 6626
DDX3X 6614
IQGAP2 6599
MUC1 6573
POLR1D 6566
PSMD12 6556
CCT8 6552
HSPA6 6514
AOC1 6509
LPO 6502
HSPA1B 6470
AHCYL1 6456
CGAS 6444
MYO9B 6424
CTNNB1 6408
ARMC8 6398
SNAP29 6390
CTSH 6360
TICAM2 6335
SRP14 6320
TICAM1 6307
LTF 6306
LRRFIP1 6302
GPI 6284
NFKB1 6277
PANX1 6267
ELMO1 6258
ARHGAP9 6256
PSMD11 6231
PPP3CA 6217
GGH 6205
FBXW11 6196
C6orf120 6192
TCN1 6182
DEGS1 6169
MAP3K8 6160
DTX4 6156
PDPK1 6136
IRAK1 6131
EP300 6129
VPS35L 6118
ITGAV 6106
PTPN6 6096
NDUFC2 6093
DNM2 6089
ATP11B 6064
DEFA1 6061
DEFA4 6057
TNFRSF1B 6045
PPBP 6042
TAX1BP1 6031
FABP5 6021
CHIT1 6012
PSMA6 5970
PSMD7 5963
DYNLL1 5952
PSMD13 5948
RNASET2 5922
CASP4 5919
PDAP1 5908
STAT6 5884
ATP6V1F 5878
CPNE3 5872
IST1 5862
CXCR2 5861
CD59 5859
SERPINB6 5854
CD46 5851
BCL10 5849
PGM1 5843
ITPR2 5842
CXCL1 5824
PTX3 5797
PSMD8 5757
BIN2 5745
ATP6V1E2 5730
WIPF2 5713
ATF1 5706
TAB1 5681
FADD 5641
TIRAP 5640
UBE2V1 5637
ADAM8 5634
CLEC7A 5608
A1BG 5559
FAF2 5554
TNIP2 5552
STBD1 5544
AZU1 5507
FOS 5460
NPC2 5458
DEFA3 5385
XRCC5 5384
IKBKG 5377
NRAS 5363
RAB24 5354
PSMA2 5339
PTPN11 5314
TARM1 5307
DGAT1 5306
POLR2L 5305
SLPI 5298
TKFC 5285
PCBP2 5283
PRKCSH 5220
VAMP8 5218
PTPRN2 5183
RAC2 5163
ACLY 5159
MAP3K1 5121
CTSG 5115
SIGLEC14 5087
CTSK 5059
TIFA 5046
PIK3R2 5010
PLCG2 5006
CEACAM8 4956
ECSIT 4918
HVCN1 4912
PLAU 4903
FTH1 4902
VAV3 4894
CRCP 4826
IL1B 4807
STING1 4791
CAMP 4785
ABCA13 4768
C4BPA 4735
IKBKE 4715
BIRC2 4692
GRAP2 4690
LIMK1 4679
UBE2D2 4657
EEA1 4641
PIK3CA 4629
PSMD3 4618
POLR2F 4604
RAP2C 4599
PPP2R1A 4589
KRT1 4537
CLEC12A 4535
CEACAM6 4509
C4A 4466
PTK2 4462
DYNLT1 4450
UBC 4439
ELMO2 4397
DUSP6 4357
SEM1 4348
ATOX1 4338
MAPK10 4325
FCGR3B 4313
B4GALT1 4292
SKP1 4287
CTSL 4231
CASP1 4224
RIPK3 4217
UNC93B1 4170
SHC1 4161
GHDC 4158
CPN2 4118
PSMB2 4084
GOLGA7 4055
MAPKAPK2 4054
CSNK2B 3969
C5 3954
SOCS1 3947
ATP6V1G1 3931
C2 3925
C4B 3922
MAPK13 3865
MAPK11 3826
SLC15A4 3724
JUN 3722
RELB 3721
KRAS 3702
DNM1 3587
STK11IP 3586
ARSA 3486
P2RX7 3475
PSMD5 3426
DDX41 3424
CREBBP 3423
PSMB1 3374
MYO1C 3310
TBK1 3229
SLCO4C1 3212
RAP1B 3206
TAB3 3160
RAB4B 3137
RPS6KA2 3087
PI3 3023
RPS6KA3 2973
SLC44A2 2700
MAGT1 2613
PSMD14 2611
PSMC2 2598
PSMB4 2523
OLR1 2486
CD177 2457
KPNB1 2430
TRIM21 2428
PPP2R5D 2421
MAP3K7 2395
MS4A3 2361
CTSC 2326
MLEC 2322
EPPIN 2251
PTPRC 2240
CST3 2206
ATF2 2085
HSP90B1 2059
SLC2A5 2044
SVIP 2035
CFD 1984
PSMC3 1976
GSDMD 1955
UBE2N 1936
SCAMP1 1868
HGSNAT 1867
NME2 1850
MMP9 1690
MAP2K7 1654
PIK3C3 1619
PSMD10 1559
SUGT1 1544
ATG5 1398
NOS1 1365
HSP90AA1 1326
ITCH 1318
AGER 1294
VRK3 1281
NHLRC3 1276
UBA52 1121
ELK1 1040
RIPK2 1025
DHX9 1019
HLA-C 1018
APEH 997
MME 916
NFASC 866
ATP7A 694
FGL2 675
HLA-B 649
RAB44 573
WIPF1 569
PYGB 492
TMEM179B 449
LRMP 441
ADGRE3 408
TXNDC5 393
NKIRAS1 375
IGHV1-2 360
NCKIPSD 328
EEF2 306
WASL 299
IGHV2-5 230
ABL1 226
GSTP1 135
IFI16 105
IGHV3-53 103
FRK -24
KCNAB2 -101
PRDX4 -144
NFKBIB -152
BAIAP2 -215
TRAF6 -229
PPP2R1B -241
HMGB1 -252
MEF2C -293
IGHV3-7 -441
PIGR -487
CD180 -600
PSMA4 -616
IGHV1-46 -618
TLR7 -625
CHI3L1 -650
IGHV3-48 -668
ATG12 -770
RAP2B -771
IGKV3-11 -781
DIAPH1 -854
PSMC5 -863
IGKV1-39 -989
IGLV7-46 -1016
MAPK12 -1074
LCP2 -1156
NFKB2 -1165
IGKV1-5 -1184
TREX1 -1198
IGLV2-8 -1294
IGKV5-2 -1298
IGHV3-23 -1317
MAPK7 -1337
COMMD3 -1363
CREB1 -1378
IGHV3-13 -1443
IGLV2-18 -1524
IGKV1-16 -1528
IGLV4-69 -1559
IGKV1D-39 -1574
AIM2 -1718
POLR2K -1783
RELA -1803
DSP -1812
IGHV1-69 -1822
IGLV10-54 -1884
LRRC7 -1966
ILF2 -1979
IGLV1-36 -2030
IGKV2-30 -2045
VTN -2046
NOS3 -2059
CALM1 -2081
UBR4 -2086
IGLV7-43 -2089
IGLV3-19 -2111
CD300A -2133
IGHV3-11 -2134
MUCL1 -2211
ATP6V1C2 -2219
PGLYRP2 -2281
IGKV3-15 -2297
C1S -2420
IGKV1-33 -2424
C4BPB -2452
POLR3K -2467
CASP2 -2471
IGHV3-30 -2484
IGKV4-1 -2532
ORM2 -2564
ADGRE5 -2571
HLA-A -2573
APRT -2766
IGKV1-17 -2871
IGLV2-23 -2878
IGLV6-57 -2885
IGHV4-59 -2892
IGLV2-11 -2905
POLR2H -2942
TLR10 -2961
MUC6 -2977
IGHV3-33 -2988
IGHV4-34 -3016
CTSV -3036
PSMB8 -3076
IGKV3-20 -3085
AGL -3136
IGHV2-70 -3138
PIN1 -3188
MUC4 -3191
DUSP7 -3211
IGLV1-44 -3258
PFKL -3277
HRAS -3382
CPNE1 -3397
ALDOC -3438
CASP10 -3446
HTN1 -3453
IGHG3 -3481
CFB -3518
AAMP -3636
SLC27A2 -3831
CD19 -3843
MIF -3863
HLA-H -3889
IGKV3D-20 -3894
STK10 -3898
PA2G4 -3916
VAV2 -4055
PIK3R4 -4062
MUC16 -4104
IGLV3-1 -4159
PAK3 -4184
CR2 -4340
HLA-E -4415
IGKC -4428
XRCC6 -4471
RBSN -4542
IGHV4-39 -4582
DPP7 -4586
MUC5B -4613
SYNGR1 -4629
AGA -4632
LGMN -4644
LEAP2 -4703
BCL2 -4704
IGLV3-21 -4735
IGLV1-40 -4788
EPX -4838
BTRC -4924
IGLV3-25 -4933
IGLV1-51 -4956
EEF1A1 -5087
IGHE -5123
OTUD5 -5132
POLR3F -5191
DHX36 -5245
IGLC7 -5281
PSMA3 -5285
CLEC10A -5299
JUP -5353
MASP2 -5358
IKBKB -5386
POLR3G -5401
CD4 -5406
IGLV8-61 -5427
IGKV1-12 -5446
S100B -5457
IGLC3 -5477
IGLC2 -5510
CFH -5562
TRAF3 -5576
IGKV2D-28 -5634
SOS1 -5700
PSMB10 -5735
IGKV2-28 -5808
IGLV5-45 -5869
IGLV3-27 -5874
MUC20 -5962
TLR9 -5999
IGLV1-47 -6018
PSMA5 -6053
PSME4 -6087
IGLC1 -6157
IGHG1 -6201
DUSP4 -6287
PDZD11 -6288
NLRP1 -6332
NF2 -6540
RAB9B -6552
CAND1 -6554
PPIA -6766
HSP90AB1 -6863
ITLN1 -6873
IGHG4 -6911
B2M -6920
PTGES2 -6926
DSC1 -6927
RPS27A -6938
TUBB -6956
SIKE1 -7060
MAPK9 -7068
IGHG2 -7250
POLR3A -7324
HRNR -7349
POLR3B -7356
IGLV3-12 -7358
BST2 -7385
POLR3C -7421
LPCAT1 -7428
PLPP5 -7430
POLR3GL -7481
UBA7 -7558
PSMA8 -7606
PTPRB -7607
ITPR1 -7629
DYNC1H1 -7685
CCR6 -7862
MRE11 -7923
HUWE1 -7977
PRKCE -8001
S100A1 -8108
IGLV2-14 -8345
CDK13 -8392
KIR2DS4 -8405
IRF3 -8517
RASGRP2 -8529
IRF7 -8657
TRIM56 -8736
SRC -8820
CCT2 -8825
PPIE -9002
CRACR2A -9069
PSMC4 -9127
TMEM63A -9137
CD209 -9143
NFATC1 -9147
CEP290 -9182
CD81 -9227
CYLD -9359
MAPK8 -9428
PIK3R1 -9505
ATP6V1G2 -9515
IRAK2 -9548
KLRC2 -9578
ENPP4 -9583
TXNIP -9600
C1R -9669
IMPDH2 -9916
PSME1 -9991
ORMDL3 -9997
ATAD3B -10079
PRKDC -10219
ITPR3 -10308
POLR3H -10310
NLRC5 -10323
PSME2 -10336
CYFIP2 -10367
ACTR1B -10514
RNF216 -10540
TMC6 -10606
MUC12 -10704
SIGIRR -10752
DSN1 -10773
ITGAL -10847
POLR1C -10899
ABI2 -10915
MALT1 -10920
HSPA8 -10922
TNFAIP3 -10950
RIPK1 -11074
MS4A2 -11106
PLCG1 -11120
BIRC3 -11125
RNF125 -11190
SERPING1 -11197
ITK -11223
UBE2L6 -11293
PSMB9 -11324
CUL1 -11330
IFIH1 -11332
CASP8 -11336
POLR3E -11383
SPTAN1 -11426
GNLY -11428
NCK1 -11454
FRMPD3 -11469
TRIM32 -11493
TLR3 -11525
CD3G -11526
ATP6V0E2 -11555
RPS6KA5 -11594
C8G -11641
FYN -11675
TXK -11676
LAT -11694
NIT2 -11695
MAP3K14 -11702
TRAF2 -11746
POLR3D -11777
RAB37 -11793
CLEC4C -11809
HMOX2 -11819
DHX58 -11824
LCK -11838
GZMM -11840
ATP8A1 -11842
TBC1D10C -11861
DDX58 -11950
PRKACB -11959
RASGRP1 -11974
FCGR3A -12005
ICAM2 -12026
ISG15 -12032
FCER1A -12046
KLRD1 -12062
CD47 -12114
PLA2G6 -12122
PRKCQ -12127
SARM1 -12134
YES1 -12142
CARD11 -12160
NFATC3 -12177
NLRC3 -12203
ATP6V0A2 -12211
PTPN4 -12220
HERC5 -12225
C3 -12262
NOD1 -12263
NFATC2 -12294
KLRK1 -12309
ZBP1 -12325
RHOF -12344
CD247 -12345
PLD4 -12365


Immune System

Immune System
519
set Immune System
setSize 1894
pANOVA 3.07e-46
s.dist 0.198
p.adjustANOVA 1.4e-43



Top enriched genes

Top 20 genes
GeneID Gene Rank
CSF2RA 9526
WASF1 9520
S100A9 9516
S100A12 9515
CTSA 9514
SIRPA 9510
IDH1 9507
RNASE2 9506
MCEMP1 9504
S100A8 9503
VAMP7 9499
CD93 9496
CR1 9486
CREG1 9483
MGST1 9482
BST1 9480
SOCS3 9476
TIMP2 9458
TALDO1 9456
HP 9454

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CSF2RA 9526.0
WASF1 9520.0
S100A9 9516.0
S100A12 9515.0
CTSA 9514.0
SIRPA 9510.0
IDH1 9507.0
RNASE2 9506.0
MCEMP1 9504.0
S100A8 9503.0
VAMP7 9499.0
CD93 9496.0
CR1 9486.0
CREG1 9483.0
MGST1 9482.0
BST1 9480.0
SOCS3 9476.0
TIMP2 9458.0
TALDO1 9456.0
HP 9454.0
CCR2 9449.0
CD36 9444.0
SERPINB2 9438.0
GCA 9436.0
PGAM1 9435.0
SERPINB1 9434.0
CTSD 9433.0
PRKACA 9429.0
ATP6V0A1 9423.0
PYGL 9417.0
FBXO9 9416.0
LAMTOR1 9411.0
FBXL5 9410.0
NLRC4 9406.0
ITGAM 9398.0
LTBR 9395.0
VIM 9394.0
PKM 9391.0
DOK3 9388.0
HK3 9385.0
SIGLEC9 9383.0
IL1RN 9381.0
CA1 9380.0
CLU 9371.0
CKAP4 9370.0
CTSB 9364.0
GNS 9360.0
RASGRP4 9359.0
RAB31 9356.0
PTAFR 9355.0
NKIRAS2 9353.0
ANPEP 9350.0
SIGLEC15 9348.0
MAOA 9346.0
LMNB1 9345.0
PGM2 9344.0
TLR8 9343.0
QPCT 9327.0
FCGR1A 9323.0
SDCBP 9311.0
CDA 9310.0
GRN 9308.0
PLD1 9306.0
GRB2 9304.0
ATP6V1A 9302.0
QSOX1 9298.0
FPR1 9295.0
IMPDH1 9294.0
CD63 9287.0
AP1S1 9286.0
DUSP3 9280.0
MNDA 9277.0
VAT1 9276.0
IFNGR1 9273.0
IL10 9272.0
TNFRSF1A 9270.0
NCF4 9268.0
CYFIP1 9265.0
LTA4H 9261.0
ARPC1B 9259.0
PADI2 9257.0
AGPAT2 9256.0
LILRA6 9250.0
ALDOA 9249.0
ATP6V0D1 9245.0
IFNGR2 9238.0
MMP8 9232.0
RAB3D 9207.0
TLR5 9201.0
TOM1 9200.0
IL17RA 9194.0
NCF2 9190.0
IL1R2 9188.0
UBE2D1 9187.0
NCSTN 9186.0
CLEC4D 9185.0
APP 9177.0
BCL6 9175.0
KLHL2 9174.0
UBE2J1 9170.0
SLC11A1 9169.0
SERPINA1 9168.0
SIGLEC16 9164.0
IL10RB 9163.0
DCTN2 9157.0
SPTB 9154.0
CD55 9145.0
GPR84 9133.0
C5AR1 9129.0
ATP6V0C 9127.0
CAT 9123.0
FCN1 9113.0
FCAR 9111.0
IRAK3 9107.0
CRISPLD2 9106.0
MAPK14 9104.0
TLR2 9103.0
TRPM2 9102.0
CD14 9097.0
FPR2 9095.0
VNN1 9092.0
NFAM1 9086.0
GSTO1 9084.0
LILRA5 9081.0
CYSTM1 9077.0
SYK 9076.0
OSCAR 9068.0
LILRA2 9066.0
ARF1 9064.0
MAP2K1 9063.0
GM2A 9059.0
ATP6V1B2 9057.0
FKBP1A 9056.0
HBB 9054.0
FCGR1B 9053.0
MGAM 9050.0
ATP6V1D 9047.0
PIK3CB 9038.0
RAP1GAP 9037.0
STXBP2 9035.0
VAPA 9033.0
CYBB 9031.0
NEU1 9029.0
INPPL1 9028.0
SLC2A3 9021.0
BRI3 9017.0
TLR4 9016.0
APAF1 9015.0
GYG1 9013.0
ACTB 9011.0
PRKCD 9008.0
DLG4 9007.0
ALOX5 9001.0
CLTC 9000.0
RETN 8998.0
LILRB4 8977.0
HCK 8976.0
CTSZ 8975.0
CD300C 8972.0
KL 8963.0
PVR 8954.0
MAPK3 8953.0
S100A11 8946.0
ITGB2 8942.0
PRDX6 8937.0
SERPINB10 8933.0
TLR1 8932.0
RAB10 8926.0
MYO10 8918.0
IL1R1 8917.0
SELL 8912.0
CRK 8906.0
CYB5R3 8903.0
NLRP3 8901.0
ARPC1A 8894.0
ITGA2B 8893.0
TGFA 8889.0
MAP2K6 8887.0
F13A1 8876.0
ZDHHC9 8872.0
LILRB3 8871.0
TRIM71 8867.0
CCR1 8865.0
HGF 8863.0
FCGR2A 8845.0
TLR6 8840.0
NUP58 8820.0
MKRN1 8817.0
CEBPD 8816.0
LAT2 8799.0
LY96 8795.0
RHOU 8794.0
RAC1 8793.0
ADAM10 8791.0
LAMP2 8786.0
HEXB 8776.0
ARG1 8759.0
LGALS3 8752.0
C1QC 8750.0
GSN 8749.0
MAP2K3 8748.0
ALPK1 8745.0
APBB1IP 8744.0
RAB7A 8742.0
TNFAIP6 8738.0
AMPD3 8732.0
AP1B1 8730.0
GLB1 8725.0
OLFM4 8724.0
BCL2L1 8700.0
MARK3 8697.0
CSF3R 8687.0
ARPC5 8686.0
FOXO3 8682.0
DNAJC5 8679.0
TIMP1 8677.0
LRG1 8674.0
FTL 8665.0
ALDH3B1 8663.0
RAB5C 8655.0
UBE2D3 8640.0
PYCARD 8638.0
PDXK 8635.0
DNASE1L1 8632.0
SNAP23 8628.0
AP2M1 8627.0
FBXL19 8620.0
TRAF7 8612.0
CDC34 8611.0
MEFV 8605.0
ATP6V0B 8598.0
CAPZA2 8597.0
ATP6V0E1 8596.0
SIAH2 8578.0
TOLLIP 8572.0
GLA 8570.0
IRS2 8569.0
CAPN1 8563.0
ACTG1 8562.0
WAS 8560.0
RNF135 8556.0
UBE2R2 8548.0
ANXA2 8544.0
ATP6V1C1 8539.0
CD68 8533.0
ASAH1 8529.0
TLN1 8525.0
MMP25 8515.0
ALAD 8514.0
RNF130 8510.0
DERA 8500.0
STX3 8492.0
ARRB2 8490.0
RHOG 8487.0
PSMB7 8485.0
FGR 8478.0
HPSE 8476.0
CLEC5A 8473.0
MAP3K3 8471.0
PTEN 8460.0
PLAC8 8452.0
NOD2 8442.0
P4HB 8440.0
P2RX1 8436.0
DNAJC3 8435.0
CEACAM1 8429.0
PLAUR 8424.0
PNP 8419.0
IFNAR1 8413.0
RAB27A 8411.0
TRIM8 8403.0
PSMD4 8402.0
EIF4G3 8400.0
HEBP2 8398.0
ATP11A 8394.0
RNF41 8389.0
DCTN4 8387.0
MAPKAPK3 8382.0
LCP1 8381.0
RILP 8377.0
CLTA 8376.0
CTSS 8372.0
TNFSF13 8370.0
WASF2 8369.0
RNF217 8367.0
RNF144B 8364.0
TMBIM1 8361.0
CPPED1 8357.0
UBAC1 8353.0
C1QB 8337.0
CD44 8333.0
S100P 8331.0
CD99 8326.0
CLEC4E 8324.0
RHOA 8319.0
PELI2 8314.0
KIF3C 8306.0
FUCA2 8304.0
SOS2 8299.0
ACAA1 8292.0
ITGB3 8291.0
TXN 8285.0
FN1 8284.0
HMOX1 8278.0
ARPC3 8277.0
CAB39 8276.0
UBE2J2 8268.0
DNAJC13 8263.0
CLEC4A 8260.0
GMFG 8259.0
MOSPD2 8252.0
PSME3 8251.0
ARL8A 8249.0
KIF5B 8239.0
PPP2CA 8234.0
PAK1 8230.0
TRIM25 8226.0
VAMP3 8222.0
JAK3 8219.0
PRCP 8218.0
ADGRG3 8204.0
C5AR2 8187.0
CFL1 8186.0
PAK2 8185.0
EGF 8179.0
PPP3R1 8175.0
SIGLEC5 8161.0
IQGAP1 8152.0
PTPN12 8151.0
RAB6A 8148.0
LYPLA1 8143.0
MYD88 8136.0
CAPZA1 8135.0
ATG7 8134.0
RAB3A 8133.0
IL6R 8132.0
FCER1G 8131.0
NECTIN2 8124.0
SEC24D 8115.0
CAP1 8111.0
ADAM17 8110.0
JAML 8107.0
PSMB5 8101.0
GAB2 8099.0
STAT3 8098.0
HSPA1A 8071.0
CD33 8069.0
ATP6V1H 8064.0
PLEKHO2 8059.0
LILRB2 8057.0
ANO6 8048.0
TMEM30A 8036.0
ATP6V1E1 8035.0
ATP6AP2 8034.0
EIF4G1 8031.0
VASP 8027.0
AP2S1 8026.0
CAPZB 8015.0
C3AR1 8012.0
MEF2A 8009.0
ORM1 7971.0
GAA 7968.0
COMMD9 7967.0
CHUK 7966.0
PSEN1 7961.0
ICAM5 7936.0
PTK2B 7935.0
COTL1 7933.0
UBE2W 7929.0
NUP214 7921.0
RNF7 7913.0
PGLYRP1 7910.0
SIGLEC7 7897.0
VAV1 7896.0
CMTM6 7891.0
CD53 7884.0
RAF1 7879.0
NEDD4L 7875.0
ACTR2 7870.0
KCMF1 7869.0
TREML1 7868.0
WSB1 7862.0
PECAM1 7855.0
PSMD6 7846.0
SIRPB1 7843.0
ANXA1 7842.0
PSTPIP1 7841.0
NLRX1 7826.0
ACTR3 7818.0
PIK3AP1 7811.0
LYN 7809.0
ICAM3 7808.0
TRAPPC1 7806.0
RAB18 7801.0
RNASEL 7797.0
PGRMC1 7795.0
FSCN1 7794.0
LILRA1 7792.0
PTPRJ 7783.0
OSM 7780.0
UBA3 7767.0
CNPY3 7761.0
PROS1 7758.0
LCN2 7755.0
DBNL 7749.0
GLIPR1 7739.0
DYNC1I2 7735.0
DOCK2 7725.0
GUSB 7723.0
PELI3 7716.0
PPP2CB 7712.0
CANT1 7707.0
PIM1 7704.0
RPS6KA1 7695.0
IFI30 7687.0
NPEPPS 7686.0
CASP9 7685.0
ZNRF1 7675.0
NCKAP1L 7673.0
LY86 7667.0
UBE2H 7663.0
CSF2RB 7661.0
SEC24A 7660.0
RGL1 7647.0
LAMP1 7631.0
MAP3K11 7626.0
PSMD9 7620.0
PTPN2 7615.0
LILRB5 7608.0
UNC13D 7607.0
ACTR10 7605.0
SPTA1 7595.0
EIF4A1 7590.0
LAMTOR3 7574.0
ARSB 7572.0
LAMTOR2 7567.0
EIF4E3 7566.0
POLR2E 7563.0
UBE2L3 7561.0
CRISP3 7552.0
TEC 7549.0
TYROBP 7539.0
CDC42 7537.0
RGL2 7520.0
ELOC 7519.0
ARPC4 7516.0
LRRC41 7515.0
TANK 7502.0
FBXO7 7498.0
MAPK1 7493.0
ROCK1 7489.0
PJA2 7486.0
ELOB 7482.0
CBL 7480.0
UBE2M 7477.0
RNASE3 7471.0
VEGFA 7467.0
NCKAP1 7462.0
SIGLEC11 7456.0
FOLR3 7451.0
CFP 7445.0
MPO 7437.0
HIF1A 7436.0
OSTF1 7426.0
CD1D 7417.0
NAPRT 7412.0
PSMD2 7411.0
FUCA1 7408.0
ARPC2 7390.0
MANBA 7386.0
IL18 7381.0
KLC3 7377.0
EIF4E2 7373.0
PLD3 7364.0
PIAS1 7361.0
IL4R 7358.0
TNFSF12 7349.0
FRS3 7343.0
UBE2F 7341.0
ITGAX 7337.0
SEC23A 7335.0
NCF1 7334.0
SHOC2 7333.0
PSMA1 7329.0
VCL 7328.0
COPB1 7321.0
ELANE 7320.0
DOCK1 7314.0
RNF182 7310.0
UBE2A 7309.0
RAP1A 7305.0
DCTN6 7300.0
LILRB1 7287.0
GDI2 7282.0
EIF4A3 7273.0
AP2A2 7257.0
PSMD1 7241.0
TUBB4B 7240.0
TNFSF13B 7238.0
LYZ 7213.0
BTK 7206.0
FLT3 7196.0
CLEC4G 7195.0
TCIRG1 7188.0
CD300LB 7186.0
LAIR1 7184.0
PLD2 7180.0
PSMB3 7171.0
SIGLEC10 7158.0
IL1RAP 7150.0
IGF2R 7149.0
PSAP 7145.0
MCL1 7133.0
MAVS 7124.0
IL27 7120.0
PILRA 7112.0
GALNS 7102.0
PRKCB 7097.0
PSMA7 7096.0
RAB14 7095.0
UBA1 7089.0
TYK2 7087.0
NBEAL2 7086.0
TRIM10 7084.0
ABI1 7082.0
PPP1CB 7064.0
SURF4 7058.0
MVP 7053.0
DNM3 7045.0
BRK1 7032.0
HSPA5 7029.0
PSMC1 7021.0
SEC61B 7013.0
TREM1 7009.0
PPP3CB 7005.0
UBE2B 7003.0
ACTR1A 7002.0
TSPAN14 6971.0
ATP8B4 6970.0
STAT5A 6965.0
TAB2 6964.0
DUSP1 6950.0
PAFAH1B2 6942.0
DYNC1LI1 6941.0
SPRED2 6936.0
DDOST 6931.0
TNFRSF12A 6928.0
STAT5B 6925.0
ITGB5 6923.0
CYBA 6922.0
TRIP12 6921.0
METTL7A 6920.0
EIF4G2 6918.0
ERP44 6905.0
CSTB 6904.0
PRKG1 6901.0
MMP1 6891.0
SUMO1 6889.0
VCP 6886.0
UBE2K 6884.0
MAN2B1 6878.0
RAPGEF2 6867.0
MAP2K4 6866.0
CXCR1 6864.0
CEACAM3 6838.0
RNASE6 6837.0
AP2A1 6832.0
CUL3 6821.0
PITPNA 6820.0
PSMB6 6813.0
WASF3 6808.0
NFKBIA 6807.0
JUNB 6806.0
RNF123 6802.0
MAP2K2 6794.0
PPP2R5B 6774.0
RNF19B 6764.0
PRTN3 6762.0
UBE2E1 6759.0
IL19 6757.0
CD300E 6742.0
CLEC6A 6730.0
PELI1 6715.0
PTPN9 6712.0
AP1M1 6711.0
ICAM1 6705.0
STOM 6704.0
H3C15 6699.5
FBXO11 6698.0
MYO5A 6693.0
RAB5B 6690.0
CD300LD 6686.0
MYH9 6685.0
YPEL5 6684.0
BPI 6666.0
IFNAR2 6665.0
PSMF1 6659.0
CD300LF 6658.0
CARD9 6648.0
CD58 6647.0
CNN2 6645.0
VWF 6641.0
UBB 6639.0
BTNL8 6638.0
PSMC6 6635.0
C1QA 6626.0
DDX3X 6614.0
IQGAP2 6599.0
MUC1 6573.0
POLR1D 6566.0
FBXW2 6560.0
PSMD12 6556.0
CCT8 6552.0
HSPA6 6514.0
AOC1 6509.0
LPO 6502.0
IRF5 6499.0
SAR1B 6479.0
HSPA1B 6470.0
AREL1 6465.0
AHCYL1 6456.0
TREML2 6454.0
SEC61A1 6449.0
CGAS 6444.0
IRF2 6427.0
MYO9B 6424.0
TREML4 6422.0
CTNNB1 6408.0
ARMC8 6398.0
SAMHD1 6397.0
SNAP29 6390.0
BATF 6386.0
YWHAB 6385.0
KBTBD7 6376.0
RCHY1 6374.0
CTSH 6360.0
CALR 6340.0
TICAM2 6335.0
PPP1CC 6330.0
SRP14 6320.0
TICAM1 6307.0
LTF 6306.0
LRRFIP1 6302.0
GPI 6284.0
UBE3C 6282.0
NFKB1 6277.0
PANX1 6267.0
ELMO1 6258.0
ARHGAP9 6256.0
PSMD11 6231.0
ASB7 6221.0
PPP3CA 6217.0
GGH 6205.0
NEDD4 6201.0
FBXW11 6196.0
C6orf120 6192.0
TCN1 6182.0
SH3KBP1 6173.0
DEGS1 6169.0
ANAPC11 6161.0
MAP3K8 6160.0
DTX4 6156.0
RGL3 6150.0
PTPN18 6149.0
PDPK1 6136.0
IRAK1 6131.0
EP300 6129.0
VPS35L 6118.0
ITGAV 6106.0
PTPN6 6096.0
NDUFC2 6093.0
DNM2 6089.0
FNTB 6081.0
ATP11B 6064.0
DEFA1 6061.0
DEFA4 6057.0
PIK3CD 6046.0
TNFRSF1B 6045.0
PPBP 6042.0
TAX1BP1 6031.0
FABP5 6021.0
CHIT1 6012.0
ORAI2 6010.0
DCTN3 5994.0
AREG 5977.0
PSMA6 5970.0
PSMD7 5963.0
DYNLL1 5952.0
PSMD13 5948.0
RNASET2 5922.0
CASP4 5919.0
PDAP1 5908.0
PPP2R5A 5897.0
STAT6 5884.0
IFITM2 5880.0
ATP6V1F 5878.0
SEC22B 5873.0
CPNE3 5872.0
IST1 5862.0
CXCR2 5861.0
CD59 5859.0
PDGFRA 5858.0
SERPINB6 5854.0
CD46 5851.0
BCL10 5849.0
PGM1 5843.0
ITPR2 5842.0
GRIN2D 5841.0
CXCL1 5824.0
RANBP9 5813.0
PTX3 5797.0
MGRN1 5794.0
UBE2Q1 5780.0
PSMD8 5757.0
RNF111 5749.0
SEC13 5748.0
BIN2 5745.0
ATP6V1E2 5730.0
PTPN1 5722.0
WIPF2 5713.0
ATF1 5706.0
TAB1 5681.0
GAB1 5679.0
PPM1B 5655.0
FADD 5641.0
TIRAP 5640.0
UBE2V1 5637.0
ADAM8 5634.0
YWHAZ 5624.0
CLEC7A 5608.0
A1BG 5559.0
FAF2 5554.0
TNIP2 5552.0
STBD1 5544.0
FBXL13 5534.0
CANX 5528.0
MSN 5524.0
KLC1 5523.0
KIF23 5510.0
AZU1 5507.0
TNFRSF8 5504.0
FBXL4 5496.0
DAPP1 5474.0
RLIM 5462.0
FOS 5460.0
NPC2 5458.0
CXCL2 5412.0
BRAP 5387.0
DEFA3 5385.0
XRCC5 5384.0
IKBKG 5377.0
NRAS 5363.0
RAB24 5354.0
PSMA2 5339.0
IL13RA1 5336.0
PTPN11 5314.0
TARM1 5307.0
DGAT1 5306.0
POLR2L 5305.0
SLPI 5298.0
PDGFA 5293.0
TKFC 5285.0
PCBP2 5283.0
PAG1 5268.0
TRIM34 5261.0
PDE6D 5250.0
PRKCSH 5220.0
CSK 5219.0
VAMP8 5218.0
PTPRN2 5183.0
RAE1 5164.0
RAC2 5163.0
ACLY 5159.0
TGFB1 5153.0
MAP3K1 5121.0
CTSG 5115.0
KLHL5 5105.0
UBE2C 5101.0
KIF20A 5096.0
SIGLEC14 5087.0
DCTN1 5078.0
CTSK 5059.0
MAPKAP1 5057.0
KLHL21 5054.0
TIFA 5046.0
HBEGF 5013.0
PIK3R2 5010.0
PLCG2 5006.0
UBE2E3 5005.0
KPNA4 4957.0
CEACAM8 4956.0
UBE2G1 4921.0
ECSIT 4918.0
CISH 4915.0
HVCN1 4912.0
PLAU 4903.0
FTH1 4902.0
KEAP1 4898.0
HERC4 4895.0
VAV3 4894.0
ASB8 4884.0
HECW2 4860.0
CNTF 4845.0
FBXL20 4844.0
LRSAM1 4831.0
CRCP 4826.0
EIF4E 4813.0
IL1B 4807.0
STING1 4791.0
CAMP 4785.0
ABCA13 4768.0
PTGS2 4753.0
UBE2S 4746.0
C4BPA 4735.0
SMARCA4 4733.0
IKBKE 4715.0
SEC61G 4708.0
BIRC2 4692.0
GRAP2 4690.0
FBXO30 4683.0
LIMK1 4679.0
UBE2D2 4657.0
EEA1 4641.0
HAVCR2 4630.0
PIK3CA 4629.0
PSMD3 4618.0
POLR2F 4604.0
RAP2C 4599.0
PPP2R1A 4589.0
LONRF1 4539.0
KRT1 4537.0
CLEC12A 4535.0
NUP50 4521.0
CDKN1A 4511.0
CEACAM6 4509.0
FBXL15 4499.0
C4A 4466.0
PTK2 4462.0
DYNLT1 4450.0
UBC 4439.0
ELMO2 4397.0
SOD2 4390.0
RNF138 4382.0
KCTD6 4371.0
RNF14 4363.0
DUSP6 4357.0
SEM1 4348.0
ATOX1 4338.0
MAPK10 4325.0
SP100 4314.0
FCGR3B 4313.0
B4GALT1 4292.0
SKP1 4287.0
DYNC1LI2 4273.0
CTF1 4260.0
CTSL 4231.0
CASP1 4224.0
RIPK3 4217.0
DYNC1I1 4187.0
SHC2 4183.0
UNC93B1 4170.0
KSR1 4167.0
SHC1 4161.0
GHDC 4158.0
CD101 4146.0
PDIA3 4128.0
CPN2 4118.0
UBR2 4099.0
PSMB2 4084.0
SQSTM1 4081.0
GOLGA7 4055.0
MAPKAPK2 4054.0
IL6ST 4025.0
FBXL8 4021.0
SIPA1 4012.0
CDC20 3998.0
IL18R1 3994.0
AP1G1 3987.0
SHC3 3974.0
CSNK2B 3969.0
NDN 3968.0
CRKL 3966.0
C5 3954.0
SOCS1 3947.0
RNF6 3943.0
STIM1 3938.0
RBX1 3934.0
ATP6V1G1 3931.0
HNRNPF 3929.0
C2 3925.0
C4B 3922.0
FGF2 3920.0
MAPK13 3865.0
EBI3 3833.0
MAPK11 3826.0
SIGLEC12 3770.0
NRG1 3750.0
KIF3B 3740.0
BIRC5 3738.0
SLC15A4 3724.0
JUN 3722.0
RELB 3721.0
WDR83 3718.0
KRAS 3702.0
VHL 3674.0
TCP1 3660.0
AKT1 3614.0
SEC24B 3608.0
DNM1 3587.0
STK11IP 3586.0
KIF4A 3585.0
REL 3527.0
ARSA 3486.0
P2RX7 3475.0
FBXO17 3474.0
IL27RA 3441.0
UBA6 3438.0
PSMD5 3426.0
DDX41 3424.0
CREBBP 3423.0
HNRNPA2B1 3380.0
PSMB1 3374.0
ASB13 3324.0
ASB1 3319.0
MYO1C 3310.0
FBXL18 3309.0
TNFSF4 3271.0
TBK1 3229.0
SLCO4C1 3212.0
RAP1B 3206.0
SOCS5 3184.0
IL1RL1 3175.0
TAB3 3160.0
RAB4B 3137.0
EGR1 3124.0
MRC1 3109.0
NUP98 3101.0
RPS6KA2 3087.0
NUP37 3074.0
NF1 3036.0
PI3 3023.0
BLMH 3017.0
LGALS9 3016.0
TAPBP 3010.0
RNF114 2998.0
UBE3A 2978.0
RPS6KA3 2973.0
PSPN 2969.0
CDC26 2923.0
ANAPC13 2921.0
UBE2V2 2902.0
POMC 2855.0
RACGAP1 2848.0
KBTBD6 2724.0
RALA 2710.0
SLC44A2 2700.0
JAK2 2691.0
EPGN 2662.0
ARAF 2644.0
IRF8 2617.0
MAGT1 2613.0
PSMD14 2611.0
PSMC2 2598.0
IL15RA 2585.0
ANGPT1 2562.0
CUL2 2526.0
PSMB4 2523.0
OLR1 2486.0
COL1A2 2469.0
CD177 2457.0
TRIM38 2449.0
TNFSF14 2443.0
KPNB1 2430.0
TRIM21 2428.0
TRIM41 2424.0
PPP2R5D 2421.0
MAP3K7 2395.0
SPSB1 2374.0
FBXO40 2368.0
MS4A3 2361.0
MICB 2355.0
CTSC 2326.0
MLEC 2322.0
MYC 2304.0
BTBD1 2263.0
EPPIN 2251.0
PTPRC 2240.0
RBCK1 2214.0
CST3 2206.0
MADCAM1 2165.0
OPRM1 2161.0
UBE2O 2123.0
RASA1 2106.0
TRIM4 2088.0
ATF2 2085.0
BTN1A1 2068.0
HSP90B1 2059.0
SLC2A5 2044.0
NANOG 2038.0
SVIP 2035.0
ICAM4 2006.0
ARRB1 1998.0
CFD 1984.0
PSMC3 1976.0
UBE4A 1970.0
GSDMD 1955.0
UBE2N 1936.0
CAMK2G 1921.0
UBE3B 1890.0
EREG 1888.0
SCAMP1 1868.0
HGSNAT 1867.0
NME2 1850.0
GBP6 1836.0
AP1M2 1832.0
UBE2E2 1779.0
FLNB 1747.0
TRIM9 1746.0
IRS1 1741.0
CXCL8 1729.0
MMP9 1690.0
PPL 1679.0
MAP2K7 1654.0
FCGR2B 1649.0
PIK3C3 1619.0
ASB9 1587.0
PSMD10 1559.0
SUGT1 1544.0
POU2F1 1537.0
NPDC1 1409.0
ATG5 1398.0
NOS1 1365.0
KLHL9 1353.0
HSP90AA1 1326.0
ASB3 1325.0
ITCH 1318.0
BRAF 1308.0
KPNA1 1296.0
AGER 1294.0
VRK3 1281.0
NHLRC3 1276.0
BOLA2 1257.0
HECTD3 1201.0
UBA52 1121.0
SEC31A 1099.0
ELK1 1040.0
RIPK2 1025.0
DHX9 1019.0
HLA-C 1018.0
HERC3 1012.0
FBXL3 1005.0
APEH 997.0
KPNA3 923.0
MME 916.0
NFASC 866.0
CUL5 834.0
IL18RAP 823.0
KIF11 787.0
NUP62 769.0
KIF2C 726.0
KLHL13 702.0
ATP7A 694.0
ZBTB16 689.0
FGL2 675.0
HLA-B 649.0
ZNRF2 633.0
STX4 606.0
RAB44 573.0
WIPF1 569.0
TNFRSF9 566.0
PYGB 492.0
FLNA 483.0
TRIM6 456.0
TMEM179B 449.0
IL33 445.0
LRMP 441.0
AKT2 433.0
ADGRE3 408.0
CSF1R 394.0
TXNDC5 393.0
MLST8 376.0
NKIRAS1 375.0
IGHV1-2 360.0
CENPE 332.0
NCKIPSD 328.0
EEF2 306.0
WASL 299.0
FBXW5 265.0
IGHV2-5 230.0
ABL1 226.0
IL17RC 193.0
GSTP1 135.0
IFI16 105.0
IGHV3-53 103.0
RASAL2 79.0
CD86 -14.0
FRK -24.0
ABHD17B -35.0
PTPN3 -85.0
ITGB1 -94.0
KCNAB2 -101.0
PRDX4 -144.0
NFKBIB -152.0
EDA -156.0
MRC2 -165.0
BAIAP2 -215.0
IFI27 -223.0
TRAF6 -229.0
PPP2R1B -241.0
HMGB1 -252.0
MEF2C -293.0
IFITM3 -359.0
IGHV3-7 -441.0
ERBB3 -472.0
GHR -479.0
PIGR -487.0
ARL2 -565.0
CD180 -600.0
PSMA4 -616.0
IGHV1-46 -618.0
TLR7 -625.0
CASP3 -632.0
CHI3L1 -650.0
CDC27 -651.0
FBXO41 -657.0
IGHV3-48 -668.0
PPP2R5E -680.0
PIANP -751.0
ATG12 -770.0
RAP2B -771.0
IGKV3-11 -781.0
ICMT -786.0
RANBP2 -820.0
DIAPH1 -854.0
PSMC5 -863.0
IGKV1-39 -989.0
RPLP0 -1000.0
IGLV7-46 -1016.0
TNFSF15 -1028.0
STUB1 -1032.0
RASAL1 -1060.0
KIF2A -1069.0
MAPK12 -1074.0
UBOX5 -1092.0
RBBP6 -1125.0
ULBP3 -1147.0
LCP2 -1156.0
NFKB2 -1165.0
IGKV1-5 -1184.0
PTPN23 -1186.0
TREX1 -1198.0
PTPN22 -1208.0
TNFRSF13B -1257.0
TRIM3 -1268.0
FBXO15 -1269.0
IGLV2-8 -1294.0
IGKV5-2 -1298.0
IGHV3-23 -1317.0
FBXL12 -1321.0
MAPK7 -1337.0
COMMD3 -1363.0
CREB1 -1378.0
GAN -1414.0
IGHV3-13 -1443.0
CRLF1 -1508.0
IGLV2-18 -1524.0
IGKV1-16 -1528.0
IGLV4-69 -1559.0
IGKV1D-39 -1574.0
OSMR -1577.0
DUSP10 -1650.0
AIM2 -1718.0
POLR2K -1783.0
RELA -1803.0
DSP -1812.0
IGHV1-69 -1822.0
TXLNA -1846.0
NRG4 -1875.0
IGLV10-54 -1884.0
LRRC7 -1966.0
ILF2 -1979.0
EDA2R -1997.0
IGLV1-36 -2030.0
ABHD17C -2037.0
IGKV2-30 -2045.0
VTN -2046.0
NOS3 -2059.0
CSF1 -2061.0
CD200 -2065.0
CALM1 -2081.0
UBR4 -2086.0
IGLV7-43 -2089.0
IGLV3-19 -2111.0
CD300A -2133.0
IGHV3-11 -2134.0
ASB14 -2170.0
IGHM -2190.0
MUCL1 -2211.0
ATP6V1C2 -2219.0
FZR1 -2233.0
AP1S2 -2261.0
ARIH1 -2279.0
PGLYRP2 -2281.0
IGKV3-15 -2297.0
FBXO6 -2300.0
UNKL -2338.0
PTPN14 -2386.0
C1S -2420.0
IGKV1-33 -2424.0
C4BPB -2452.0
HLA-G -2457.0
POLR3K -2467.0
CASP2 -2471.0
IGHV3-30 -2484.0
HECTD1 -2490.0
IGKV4-1 -2532.0
SOCS2 -2538.0
ORM2 -2564.0
SEC24C -2569.0
ADGRE5 -2571.0
HLA-A -2573.0
SMURF1 -2591.0
CD1A -2596.0
LTN1 -2597.0
ENAH -2707.0
AP2B1 -2709.0
KIF18A -2742.0
ASB6 -2763.0
APRT -2766.0
IGKV1-17 -2871.0
IGLV2-23 -2878.0
IGLV6-57 -2885.0
IGHV4-59 -2892.0
IGLV2-11 -2905.0
RAPGEF3 -2911.0
POLR2H -2942.0
TLR10 -2961.0
MUC6 -2977.0
IGHV3-33 -2988.0
PHB -2995.0
SIAH1 -3000.0
IGHV4-34 -3016.0
CCL3 -3027.0
CTSV -3036.0
NUP85 -3049.0
PSMB8 -3076.0
IGKV3-20 -3085.0
AGL -3136.0
IGHV2-70 -3138.0
PIN1 -3188.0
MUC4 -3191.0
DUSP7 -3211.0
KIF15 -3249.0
IGLV1-44 -3258.0
LAMA5 -3263.0
PFKL -3277.0
FGFR4 -3293.0
PDCD1LG2 -3326.0
CUL7 -3334.0
KSR2 -3361.0
HRAS -3382.0
CPNE1 -3397.0
TNFSF11 -3409.0
FRS2 -3433.0
ALDOC -3438.0
ADAR -3442.0
CASP10 -3446.0
HTN1 -3453.0
IGHG3 -3481.0
CFB -3518.0
SPTBN5 -3531.0
AIP -3566.0
AAMP -3636.0
TRIM11 -3671.0
FBXO22 -3709.0
PTPN20 -3783.0
DAB2IP -3826.0
SLC27A2 -3831.0
CD19 -3843.0
MIF -3863.0
PAQR3 -3864.0
HLA-H -3889.0
IGKV3D-20 -3894.0
STK10 -3898.0
PA2G4 -3916.0
DYNLL2 -3980.0
MYLIP -3991.0
SPSB2 -4034.0
INPP5D -4038.0
STX1A -4052.0
VAV2 -4055.0
PIK3R4 -4062.0
DCTN5 -4086.0
MUC16 -4104.0
RASGRF1 -4123.0
IGLV3-1 -4159.0
PAK3 -4184.0
KBTBD8 -4224.0
FCER2 -4230.0
FGF7 -4247.0
TNFRSF17 -4308.0
RASA2 -4320.0
CR2 -4340.0
COLEC12 -4367.0
IGHD -4407.0
HLA-E -4415.0
IGKC -4428.0
XRCC6 -4471.0
TNFRSF13C -4479.0
RBSN -4542.0
TRIM2 -4562.0
IGHV4-39 -4582.0
DPP7 -4586.0
MUC5B -4613.0
PTPRA -4626.0
SYNGR1 -4629.0
AGA -4632.0
LGMN -4644.0
RCE1 -4674.0
LEAP2 -4703.0
BCL2 -4704.0
UBR1 -4734.0
IGLV3-21 -4735.0
CNKSR2 -4781.0
OPRD1 -4782.0
IGLV1-40 -4788.0
CD22 -4791.0
LNX1 -4796.0
HLA-DQA2 -4806.0
EPX -4838.0
SOD1 -4862.0
BTRC -4924.0
KIF26A -4925.0
IGLV3-25 -4933.0
IGLV1-51 -4956.0
HLA-DRB5 -4971.0
CD40 -4995.0
ANAPC10 -5000.0
IL15 -5043.0
BTNL9 -5071.0
FBXO27 -5074.0
EEF1A1 -5087.0
IGHE -5123.0
SPTBN2 -5129.0
OTUD5 -5132.0
SH3RF1 -5151.0
CD79A -5158.0
HCST -5160.0
HLA-DOB -5177.0
ANAPC7 -5181.0
POLR3F -5191.0
BTBD6 -5202.0
MICA -5227.0
DHX36 -5245.0
IGLC7 -5281.0
PSMA3 -5285.0
CLEC10A -5299.0
ERAP2 -5338.0
FGFR1 -5352.0
JUP -5353.0
MASP2 -5358.0
NFKBIE -5377.0
IKBKB -5386.0
BLK -5388.0
DTX3L -5393.0
POLR3G -5401.0
CD4 -5406.0
IL17RE -5421.0
NEFL -5425.0
IGLV8-61 -5427.0
IGKV1-12 -5446.0
S100B -5457.0
IGLC3 -5477.0
IGLC2 -5510.0
AP1S3 -5522.0
CFH -5562.0
NUP42 -5564.0
TRAF3 -5576.0
ASB4 -5604.0
BTLA -5625.0
IGKV2D-28 -5634.0
MX2 -5647.0
IFI35 -5670.0
SOS1 -5700.0
RASGEF1A -5704.0
DLG2 -5717.0
FNTA -5724.0
PSMB10 -5735.0
MTAP -5790.0
IGKV2-28 -5808.0
OSBPL1A -5816.0
TRIB3 -5843.0
HACE1 -5851.0
IGLV5-45 -5869.0
IGLV3-27 -5874.0
MUC20 -5962.0
KIR2DL4 -5995.0
TLR9 -5999.0
IGLV1-47 -6018.0
PSMA5 -6053.0
SEH1L -6069.0
CDC16 -6071.0
PSME4 -6087.0
TNFSF9 -6091.0
FBXL14 -6145.0
RNF34 -6150.0
IGLC1 -6157.0
MRAS -6172.0
IGHG1 -6201.0
IFITM1 -6264.0
KLHL11 -6286.0
DUSP4 -6287.0
PDZD11 -6288.0
PDE12 -6298.0
RNF220 -6303.0
NUP153 -6321.0
NLRP1 -6332.0
CD70 -6370.0
HLA-DQB1 -6416.0
FBXO10 -6427.0
TNFRSF14 -6445.0
IL17RB -6506.0
NF2 -6540.0
RAB9B -6552.0
CAND1 -6554.0
FBXW7 -6600.0
FGF23 -6622.0
IL17C -6641.0
ANAPC4 -6644.0
FBXL16 -6648.0
DUSP16 -6655.0
TNFRSF4 -6657.0
ASB16 -6665.0
TRIM36 -6670.0
UFL1 -6680.0
EDAR -6693.0
TRIM14 -6730.0
SIGLEC8 -6747.0
PPIA -6766.0
PDCD1 -6792.0
PEA15 -6825.0
SPRED3 -6835.0
CD80 -6841.0
ICOSLG -6859.0
HSP90AB1 -6863.0
ITLN1 -6873.0
KPNA2 -6910.0
IGHG4 -6911.0
B2M -6920.0
PTGES2 -6926.0
DSC1 -6927.0
RPS27A -6938.0
TUBB -6956.0
CCND1 -6970.0
TRIM5 -6975.0
MT2A -6990.0
TPR -7028.0
SIKE1 -7060.0
MAPK9 -7068.0
TNFSF8 -7086.0
CNKSR1 -7089.0
ORAI1 -7096.0
GBP2 -7142.0
IL2RA -7161.0
POM121C -7188.0
BLNK -7227.0
IGHG2 -7250.0
TRAV8-4 -7261.0
RNF25 -7289.0
TNF -7308.0
POLR3A -7324.0
HRNR -7349.0
POLR3B -7356.0
IGLV3-12 -7358.0
FBXW9 -7360.0
ERAP1 -7370.0
BST2 -7385.0
ANAPC2 -7407.0
POLR3C -7421.0
LPCAT1 -7428.0
PLPP5 -7430.0
CD79B -7443.0
PPP5C -7462.0
ZEB1 -7466.0
POLR3GL -7481.0
TRAT1 -7535.0
UBA7 -7558.0
CD274 -7563.0
PSMA8 -7606.0
PTPRB -7607.0
ITPR1 -7629.0
IL31RA -7636.0
LRR1 -7643.0
DYNC1H1 -7685.0
TRIM45 -7697.0
TNFRSF18 -7726.0
NUP133 -7762.0
SPTBN1 -7764.0
IL12A -7823.0
RET -7856.0
CCR6 -7862.0
MRE11 -7923.0
TRIM46 -7951.0
HUWE1 -7977.0
PRKCE -8001.0
TNFRSF11A -8033.0
UBE2G2 -8035.0
HLA-DRB1 -8075.0
S100A1 -8108.0
CD226 -8138.0
CXCL10 -8160.0
CD8B -8188.0
SKP2 -8279.0
POM121 -8299.0
UBA5 -8300.0
FBXO2 -8324.0
DLG1 -8336.0
IGLV2-14 -8345.0
FBXW12 -8358.0
KLHL42 -8367.0
KLC4 -8376.0
AAAS -8389.0
BTN2A1 -8390.0
CDK13 -8392.0
KIR2DS4 -8405.0
LTB -8406.0
PRKG2 -8477.0
NUP54 -8479.0
TRIM37 -8494.0
IRF1 -8510.0
IRF3 -8517.0
RASGRP2 -8529.0
IL7 -8554.0
RORC -8573.0
PDGFB -8577.0
FGF22 -8607.0
KIFAP3 -8619.0
LAIR2 -8627.0
SPRED1 -8639.0
IRF7 -8657.0
SH2B1 -8670.0
GFRA2 -8689.0
PML -8693.0
TRIM56 -8736.0
FGF9 -8761.0
IFNLR1 -8808.0
SRC -8820.0
CCT2 -8825.0
CCR5 -8861.0
KIF5C -8865.0
KIF5A -8869.0
CLEC2B -8920.0
IL20RB -8921.0
IRF4 -8967.0
CD34 -8972.0
TPP2 -8977.0
GBP3 -8979.0
PPIE -9002.0
HECTD2 -9020.0
KLC2 -9059.0
CRACR2A -9069.0
TRIM26 -9081.0
EIF2AK2 -9116.0
PSMC4 -9127.0
TMEM63A -9137.0
SYNGAP1 -9140.0
CD209 -9143.0
NFATC1 -9147.0
KIR2DL3 -9153.0
CEP290 -9182.0
DET1 -9199.0
FBXL22 -9210.0
S1PR1 -9211.0
BRWD1 -9221.0
CD81 -9227.0
CCNF -9262.0
SIGLEC6 -9283.0
HERC1 -9297.0
CYLD -9359.0
DUSP2 -9373.0
HLA-DQB2 -9401.0
RASGRP3 -9414.0
CD200R1 -9422.0
MAPK8 -9428.0
ICOS -9434.0
THOP1 -9447.0
FOXO1 -9465.0
CIITA -9470.0
PIK3R1 -9505.0
HLA-DMB -9507.0
ATP6V1G2 -9515.0
NUP43 -9517.0
IRF6 -9518.0
TRBV7-9 -9539.0
IRAK2 -9548.0
OAS1 -9574.0
KLRC2 -9578.0
ENPP4 -9583.0
TRIM69 -9591.0
TXNIP -9600.0
PJA1 -9611.0
LNPEP -9618.0
FBXO44 -9627.0
C1R -9669.0
RICTOR -9670.0
GBP1 -9672.0
TRAV29DV5 -9673.0
TRIM35 -9697.0
LMO7 -9709.0
IL16 -9726.0
TRPC1 -9736.0
IL11RA -9753.0
MTOR -9767.0
RNF115 -9777.0
HSPA9 -9780.0
CD27 -9812.0
RAPGEF1 -9826.0
LTA -9851.0
HLA-DMA -9886.0
FLT3LG -9894.0
TRAV19 -9915.0
IMPDH2 -9916.0
PTPN13 -9962.0
PSME1 -9991.0
ORMDL3 -9997.0
FBXW8 -10013.0
SNRPA1 -10023.0
ATAD3B -10079.0
WWP1 -10106.0
IL32 -10122.0
TRIM17 -10141.0
RASGRF2 -10175.0
RNF19A -10197.0
CD28 -10202.0
PRKDC -10219.0
NUP155 -10233.0
IFNG -10277.0
LAG3 -10294.0
ITPR3 -10308.0
POLR3H -10310.0
NLRC5 -10323.0
PSME2 -10336.0
SMURF2 -10340.0
CTLA4 -10363.0
CYFIP2 -10367.0
CD40LG -10384.0
IL4 -10399.0
PRLR -10410.0
NUP107 -10421.0
TRBV12-3 -10436.0
TRIM39 -10438.0
CD8A -10476.0
ACTR1B -10514.0
IL23A -10538.0
RNF216 -10540.0
RNF126 -10545.0
IL7R -10546.0
CRTAM -10549.0
NUP160 -10557.0
IL18BP -10561.0
TNFRSF25 -10588.0
IL10RA -10594.0
TMC6 -10606.0
FBXO32 -10607.0
NUP35 -10611.0
STAT2 -10637.0
IP6K2 -10651.0
HERC2 -10658.0
TRIM62 -10661.0
KLHL25 -10671.0
ABHD17A -10672.0
ALOX15 -10676.0
MUC12 -10704.0
NUP210 -10726.0
ABCE1 -10729.0
SIGIRR -10752.0
DSN1 -10773.0
UBE3D -10777.0
TAP1 -10787.0
FBXO21 -10790.0
SEC61A2 -10798.0
OASL -10836.0
KLRC1 -10837.0
ITGAL -10847.0
TRIM22 -10849.0
KIR2DL1 -10859.0
PTPN7 -10868.0
TP53 -10893.0
POLR1C -10899.0
UBE2Z -10912.0
ABI2 -10915.0
MALT1 -10920.0
HSPA8 -10922.0
EDARADD -10943.0
TNFAIP3 -10950.0
JAK1 -10955.0
ANAPC5 -10967.0
CCL5 -10985.0
KIT -11004.0
IL24 -11009.0
DZIP3 -11017.0
NCR3 -11035.0
ITGA4 -11043.0
GBP5 -11062.0
THEM4 -11069.0
MIB2 -11073.0
RIPK1 -11074.0
GLMN -11075.0
MS4A2 -11106.0
PLCG1 -11120.0
BIRC3 -11125.0
HLA-F -11138.0
CLCF1 -11150.0
IRF9 -11154.0
EIF4A2 -11157.0
RNF125 -11190.0
SERPING1 -11197.0
UBE2D4 -11203.0
RASA4 -11206.0
IL5RA -11211.0
ITK -11223.0
HNRNPDL -11232.0
KLRG1 -11238.0
PPP2R5C -11265.0
PEBP1 -11270.0
IFIT5 -11287.0
UBE2L6 -11293.0
CD3E -11302.0
CDC23 -11304.0
NUP205 -11321.0
PDE3B -11322.0
PSMB9 -11324.0
PILRB -11325.0
CUL1 -11330.0
IFIH1 -11332.0
CASP8 -11336.0
CTSO -11366.0
POLR3E -11383.0
KIR3DL1 -11385.0
NUP88 -11397.0
CD3D -11401.0
KLHL22 -11407.0
CD74 -11419.0
KIR3DL2 -11420.0
SPTAN1 -11426.0
GNLY -11428.0
RAG1 -11432.0
NCK1 -11454.0
RNF4 -11467.0
FRMPD3 -11469.0
TRAC -11482.0
KLHL20 -11483.0
TRIM32 -11493.0
CDH1 -11500.0
TLR3 -11525.0
CD3G -11526.0
PDGFRB -11545.0
KCTD7 -11546.0
CTSF -11553.0
UBE2Q2 -11554.0
ATP6V0E2 -11555.0
RPS6KA5 -11594.0
ISG20 -11609.0
TRAIP -11615.0
NUP93 -11620.0
NUP188 -11624.0
KLHL3 -11635.0
DUSP8 -11639.0
C8G -11641.0
FYN -11675.0
TXK -11676.0
LAT -11694.0
NIT2 -11695.0
MAP3K14 -11702.0
NCAM1 -11706.0
STAT1 -11727.0
BTN2A2 -11730.0
SMAD3 -11745.0
TRAF2 -11746.0
FBXW4 -11757.0
POLR3D -11777.0
VAMP2 -11779.0
FGFR2 -11785.0
RAB37 -11793.0
TAP2 -11807.0
CLEC4C -11809.0
HLA-DOA -11812.0
CAMK2D -11816.0
HMOX2 -11819.0
RASA3 -11820.0
PDCD4 -11822.0
DHX58 -11824.0
CD160 -11835.0
LCK -11838.0
GZMM -11840.0
ATP8A1 -11842.0
FBXO4 -11843.0
GBP4 -11848.0
AKT3 -11849.0
TBC1D10C -11861.0
IFI6 -11882.0
KPNA5 -11893.0
RNF213 -11905.0
DLG3 -11922.0
NCR3LG1 -11944.0
BTN3A2 -11945.0
ZAP70 -11949.0
DDX58 -11950.0
FBXO31 -11953.0
PRKACB -11959.0
ANAPC1 -11962.0
KIF3A -11972.0
RASGRP1 -11974.0
CCL4 -11976.0
ASB2 -11978.0
RORA -11979.0
PRR5 -11985.0
TRIM68 -11989.0
HLA-DQA1 -11992.0
IL12RB2 -11994.0
FCGR3A -12005.0
TRBC1 -12006.0
HLA-DRA -12009.0
RASAL3 -12014.0
PIK3R3 -12015.0
ICAM2 -12026.0
ISG15 -12032.0
IFIT3 -12037.0
FCER1A -12046.0
IL2RG -12050.0
IL3RA -12057.0
KLRD1 -12062.0
XAF1 -12073.0
ARIH2 -12090.0
LILRA4 -12092.0
CD96 -12097.0
IFIT2 -12108.0
CD47 -12114.0
IL12RB1 -12115.0
PLA2G6 -12122.0
PRKCQ -12127.0
SLAMF7 -12130.0
OAS2 -12131.0
SARM1 -12134.0
MX1 -12138.0
RALGDS -12140.0
YES1 -12142.0
MEX3C -12144.0
CD1C -12147.0
CARD11 -12160.0
SH2D1A -12167.0
NDC1 -12173.0
NFATC3 -12177.0
IL9R -12179.0
SIGLEC1 -12182.0
ITGB7 -12187.0
OAS3 -12188.0
GATA3 -12191.0
SLAMF6 -12193.0
NLRC3 -12203.0
HERC6 -12205.0
EVL -12207.0
ATP6V0A2 -12211.0
USP18 -12214.0
PTPN4 -12220.0
HERC5 -12225.0
DUSP5 -12227.0
RSAD2 -12233.0
HLA-DPB1 -12248.0
IL21R -12256.0
C3 -12262.0
NOD1 -12263.0
KLRB1 -12265.0
CLEC2D -12275.0
NFATC2 -12294.0
CBLB -12303.0
KLRK1 -12309.0
HLA-DPA1 -12316.0
IFIT1 -12318.0
ERBB2 -12320.0
ZBP1 -12325.0
STAT4 -12336.0
BTN3A3 -12339.0
CCL2 -12341.0
KLRF1 -12343.0
RHOF -12344.0
CD247 -12345.0
IL2RB -12347.0
KIF22 -12358.0
SH2D1B -12360.0
BTN3A1 -12362.0
PLD4 -12365.0
NCR1 -12370.0
FASLG -12371.0


Membrane Trafficking

Membrane Trafficking
631
set Membrane Trafficking
setSize 559
pANOVA 5.33e-36
s.dist 0.309
p.adjustANOVA 1.82e-33



Top enriched genes

Top 20 genes
GeneID Gene Rank
VAMP7 9499
F5 9485
RAB32 9463
RAB13 9440
PLIN3 9437
GNS 9360
RAB31 9356
GRB2 9304
TBC1D2 9301
ITSN1 9289
AP1S1 9286
YWHAG 9264
AGFG1 9211
ARF4 9191
PLA2G4A 9180
APP 9177
SORT1 9171
SERPINA1 9168
DCTN2 9157
SPTB 9154

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
VAMP7 9499
F5 9485
RAB32 9463
RAB13 9440
PLIN3 9437
GNS 9360
RAB31 9356
GRB2 9304
TBC1D2 9301
ITSN1 9289
AP1S1 9286
YWHAG 9264
AGFG1 9211
ARF4 9191
PLA2G4A 9180
APP 9177
SORT1 9171
SERPINA1 9168
DCTN2 9157
SPTB 9154
CD55 9145
KDELR1 9142
SBF2 9078
ARF1 9064
RAB1A 9052
YWHAE 9045
GABARAPL2 9044
PICALM 9022
RAB3IL1 9005
CLTC 9000
CUX1 8986
CTSZ 8975
CLTCL1 8965
RAB10 8926
STX10 8921
TBC1D14 8897
ARPC1A 8894
TGFA 8889
CHMP4B 8866
GALNT2 8843
NSF 8829
CPD 8824
RALGAPA2 8804
RAC1 8793
CHMP2A 8780
ANK1 8771
EXOC6 8762
BICD2 8746
RAB7A 8742
AP1B1 8730
TGOLN2 8714
UBAP1 8701
RAB11A 8688
ARPC5 8686
FTL 8665
RAB5C 8655
YWHAH 8649
BLOC1S1 8630
SNAP23 8628
AP2M1 8627
CAPZA2 8597
FNBP1L 8551
AMPH 8532
ARRB2 8490
RAB27A 8411
DCTN4 8387
CLTA 8376
COPA 8366
AP3B1 8365
RIN2 8355
CHMP3 8349
RAB1B 8313
KIF3C 8306
ARPC3 8277
HIP1 8258
KIF5B 8239
VAMP3 8222
KIF1B 8184
EGF 8179
REPS2 8154
RAB6A 8148
CAPZA1 8135
RAB3A 8133
PACSIN2 8123
SEC24D 8115
DAB2 8112
TBC1D10B 8078
EPN1 8045
MAP1LC3B 8043
TOR1A 8033
AP2S1 8026
CAPZB 8015
VPS37C 8010
GJD3 7996
TMED7 7950
RAB4A 7941
DENND3 7938
MAN1A1 7927
STX6 7906
GABARAP 7904
COPB2 7902
ARF5 7885
AP3S1 7874
ACTR2 7870
SNX2 7861
ACTR3 7818
FCHO2 7807
TRAPPC1 7806
RAB18 7801
KIF1C 7799
TSG101 7786
CNIH1 7779
DENND5A 7736
DYNC1I2 7735
ARF3 7732
KDELR2 7728
SEC24A 7660
VPS25 7638
SH3GL1 7625
ACTR10 7605
RIN1 7602
SPTA1 7595
COPG2 7594
VPS54 7568
ARPC4 7516
RHOQ 7511
COPG1 7509
CBL 7480
RABGEF1 7466
SNAPIN 7443
DENND1A 7441
NAA38 7435
STXBP3 7424
MVB12A 7400
ARPC2 7390
KLC3 7377
SEC23A 7335
COPB1 7321
DCTN6 7300
GDI2 7282
RAB33B 7267
AP2A2 7257
TMED9 7167
STX5 7166
TFG 7160
IGF2R 7149
ULK1 7125
TRAPPC3 7114
RAB39A 7113
RAB5A 7103
MCFD2 7099
RAB14 7095
LMAN2 7080
SURF4 7058
DNM3 7045
TBC1D1 7034
F8 7022
SNX18 7017
ACTR1A 7002
PAFAH1B2 6942
DYNC1LI1 6941
LMAN2L 6937
COPE 6896
AP2A1 6832
RIC1 6824
PPP6C 6819
BLOC1S6 6815
GAPVD1 6799
DNASE2 6745
TRAPPC8 6735
AP1M1 6711
MYO5A 6693
RAB5B 6690
MYH9 6685
UBB 6639
MAN2A2 6625
MON1B 6612
GORASP1 6606
GRK3 6593
COPS7A 6590
RAB8B 6529
GALNT1 6508
NEDD8 6482
SAR1B 6479
VPS37A 6467
TBC1D7 6452
OCRL 6442
RAB43 6433
AP4E1 6419
SNAP29 6390
YWHAB 6385
PREB 6368
TRAPPC12 6310
COL7A1 6304
SYNJ1 6296
GOLGA2 6203
VTA1 6185
LDLR 6183
SH3KBP1 6173
RAB21 6165
STAM2 6159
COPS2 6139
DNM2 6089
CYTH4 6085
CLTB 6084
GRK2 6068
RAB6B 6053
TMED2 6052
COPS3 6005
KIF13B 5998
DCTN3 5994
AREG 5977
SNF8 5973
DYNLL1 5952
UBQLN2 5939
CTTN 5930
DENND2C 5898
SEC22B 5873
CD59 5859
YIPF6 5857
ACBD3 5816
RAB3GAP1 5768
SEC13 5748
GDI1 5739
CHMP2B 5714
EXOC1 5670
RAB36 5636
YWHAZ 5624
HPS1 5605
EXOC4 5591
ARCN1 5580
MIA2 5574
KLC1 5523
KIF23 5510
TMEM115 5508
CHMP6 5499
PRKAG1 5476
PAFAH1B1 5470
TRAPPC9 5333
GOLGA5 5322
TRAPPC11 5319
VTI1A 5302
GOLIM4 5271
PPP6R1 5263
SCARB2 5255
VAMP8 5218
VPS4B 5212
YKT6 5205
TRAPPC5 5191
MVB12B 5175
UBQLN1 5108
KIF20A 5096
DCTN1 5078
ITSN2 5060
SYT1 5056
HBEGF 5013
CHMP5 4943
EXOC7 4924
FTH1 4902
AGPAT3 4809
GJB6 4761
EXOC3 4724
STX18 4648
DNAJC6 4640
SEC16A 4619
RGP1 4538
HGS 4513
UBC 4439
RABEPK 4434
USP6NL 4433
RAB3GAP2 4429
PAFAH1B3 4417
RAB11B 4402
COPS5 4361
DYNC1LI2 4273
COG7 4269
KIF9 4253
CCZ1 4242
VPS28 4199
DYNC1I1 4187
USO1 4154
TRAPPC6B 4147
EXOC5 4141
NAPG 4139
EPS15 4138
RAB9A 4088
COPZ1 4035
AP1G1 3987
RAB35 3981
VPS37B 3908
RAB8A 3880
GGA3 3816
CLINT1 3815
TBC1D13 3782
KIF3B 3740
STX16 3717
ARFGAP3 3714
TBC1D15 3665
EPS15L1 3655
AKT1 3614
SEC24B 3608
DNM1 3587
KIF4A 3585
STON2 3569
SCFD1 3525
PIP5K1C 3419
TBC1D16 3409
NECAP2 3387
RAB27B 3386
MYO1C 3310
PPP6R3 3261
PUM1 3250
RAB3IP 3237
TBC1D24 3200
VAMP4 3191
ALS2 3176
KIAA0319 3163
DENND4B 3139
DENND6B 2993
RACGAP1 2848
KIF16B 2785
GCC1 2730
TMED3 2720
RALA 2710
EPGN 2662
STON1 2574
GAK 2570
KIF27 2549
TMF1 2535
VPS45 2496
CFTR 2416
GOLGA1 2415
CHMP4A 2400
CSNK1D 2390
TRIP10 2343
CTSC 2326
GGA1 2310
CHM 2273
NECAP1 2220
RABGAP1 2052
PRKAG2 2015
ARRB1 1998
EREG 1888
AP1M2 1832
COPS4 1776
COPS6 1637
SFN 1615
TFRC 1524
NAPA 1432
TBC1D8B 1417
ARF6 1377
LRP2 1307
PRKAB1 1302
STAM 1285
KIF6 1147
UBA52 1121
TF 1102
SEC31A 1099
GJC2 1083
DTNBP1 1014
CCZ1B 990
USE1 938
KIF11 787
VPS4A 784
KIF2C 726
CNIH2 654
STX4 606
GJC1 518
SYT2 461
CYTH2 442
AKT2 433
TXNDC5 393
SYS1 386
CENPE 332
SEC16B 330
TMED10 323
WASL 299
AVPR2 291
NBAS 208
ANKRD27 186
AP4M1 138
ZW10 31
EXOC8 -1
COG4 -6
TBC1D20 -18
TBC1D3 -66
KIF18B -143
GOSR1 -182
KIFC1 -249
FNBP1 -311
VPS53 -341
COG8 -346
SNX9 -430
SEC23IP -468
DENND6A -562
TRIP11 -579
BET1 -594
TSC2 -804
RAB12 -856
SCOC -885
KIF2A -1069
MAN2A1 -1349
GOSR2 -1456
CHML -1515
RAB7B -1531
KIFC2 -1642
ARFGAP1 -1942
MAN1A2 -2055
CALM1 -2081
KDELR3 -2117
TSC1 -2118
TOR1B -2136
AP1S2 -2261
TRAPPC2L -2299
FCHO1 -2392
TRAPPC13 -2479
SEC24C -2569
AP2B1 -2709
KIF18A -2742
NAPB -2780
MON1A -2910
ARFIP2 -3197
KIF15 -3249
COG5 -3259
SNX5 -3305
SPTBN5 -3531
TPD52L1 -3542
VPS52 -3619
RAB41 -3974
DYNLL2 -3980
SH3D19 -4011
GOLGA4 -4064
DCTN5 -4086
EPN2 -4100
RALGAPB -4138
SEC22C -4248
DENND5B -4249
GBF1 -4290
GPS1 -4517
ANK3 -4919
KIF26A -4925
GJA3 -4935
SEC22A -5052
ARL1 -5063
SPTBN2 -5129
ASPSCR1 -5154
PIK3C2A -5194
GOLGB1 -5370
CD4 -5406
COG3 -5426
AP1S3 -5522
DENND4A -5540
AP1G2 -5590
AP4S1 -5731
ARFGAP2 -5786
COG6 -5811
MIA3 -6245
ANKRD28 -6250
TJP1 -6374
RAB9B -6552
VPS51 -6584
GGA2 -6587
KIF21B -6702
TRAPPC4 -6712
SYT11 -6763
KIF28P -6770
MAN1C1 -6804
VPS36 -6848
RPS27A -6938
REPS1 -7137
AP4B1 -7235
YWHAQ -7340
BICD1 -7365
TBC1D25 -7372
DENND1C -7377
BET1L -7405
BLOC1S4 -7493
ARFRP1 -7561
C2CD5 -7570
DENND4C -7574
BNIP1 -7588
DYNC1H1 -7685
GCC2 -7725
SPTBN1 -7764
EXOC2 -7780
KIF20B -7822
COG2 -7917
PRKAB2 -8172
CYTH3 -8200
ALS2CL -8315
DENND2A -8355
KLC4 -8376
SYNJ2 -8511
M6PR -8519
KIFAP3 -8619
BLOC1S3 -8703
TRAPPC2 -8704
RAB38 -8714
TBC1D17 -8716
COPS8 -8755
CHMP7 -8802
SRC -8820
KIF5C -8865
KIF5A -8869
CNIH3 -9011
KLC2 -9059
AAK1 -9190
DENND1B -9284
LDLRAP1 -9326
TRAPPC10 -9369
LNPEP -9618
TPD52 -9644
NAA30 -9696
COPS7B -9775
RAB30 -9844
POLG -9889
SYTL1 -10104
RINT1 -10112
RINL -10326
SBF1 -10530
IL7R -10546
HIP1R -10615
LMAN1 -10630
TBC1D4 -10754
COPZ2 -10863
TRAPPC6A -10917
HSPA8 -10922
RAB33A -10940
STX17 -11006
DVL2 -11152
RHOBTB3 -11172
CD3D -11401
MYO6 -11410
BIN1 -11411
SPTAN1 -11426
NAA35 -11524
CD3G -11526
RAB39B -11529
HPS4 -11558
FZD4 -11650
KIF26B -11663
KIF19 -11733
SLC2A8 -11749
RABEP1 -11754
OPTN -11766
VAMP2 -11779
KIF21A -11837
AKT3 -11849
TBC1D10C -11861
ADRB2 -11892
MADD -11899
KIF3A -11972
TBC1D10A -12025
PLA2G6 -12122
COG1 -12125
DENND2D -12293
CYTH1 -12314
KIF22 -12358
PACSIN1 -12374


Vesicle-mediated transport

Vesicle-mediated transport
1312
set Vesicle-mediated transport
setSize 650
pANOVA 1.64e-31
s.dist 0.268
p.adjustANOVA 4.48e-29



Top enriched genes

Top 20 genes
GeneID Gene Rank
VAMP7 9499
STAB1 9495
F5 9485
RAB32 9463
CD163 9462
HP 9454
CD36 9444
RAB13 9440
PLIN3 9437
GNS 9360
RAB31 9356
GRB2 9304
TBC1D2 9301
ITSN1 9289
AP1S1 9286
YWHAG 9264
AGFG1 9211
ARF4 9191
PLA2G4A 9180
APP 9177

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
VAMP7 9499
STAB1 9495
F5 9485
RAB32 9463
CD163 9462
HP 9454
CD36 9444
RAB13 9440
PLIN3 9437
GNS 9360
RAB31 9356
GRB2 9304
TBC1D2 9301
ITSN1 9289
AP1S1 9286
YWHAG 9264
AGFG1 9211
ARF4 9191
PLA2G4A 9180
APP 9177
SORT1 9171
SERPINA1 9168
DCTN2 9157
SPTB 9154
CD55 9145
KDELR1 9142
LRP1 9080
SBF2 9078
ARF1 9064
HBB 9054
RAB1A 9052
YWHAE 9045
GABARAPL2 9044
PICALM 9022
RAB3IL1 9005
CLTC 9000
HBA1 8990
CUX1 8986
CTSZ 8975
CLTCL1 8965
RAB10 8926
STX10 8921
TBC1D14 8897
ARPC1A 8894
TGFA 8889
CHMP4B 8866
GALNT2 8843
NSF 8829
CPD 8824
RALGAPA2 8804
RAC1 8793
CHMP2A 8780
ANK1 8771
EXOC6 8762
BICD2 8746
RAB7A 8742
AP1B1 8730
TGOLN2 8714
UBAP1 8701
RAB11A 8688
ARPC5 8686
FTL 8665
RAB5C 8655
YWHAH 8649
BLOC1S1 8630
SNAP23 8628
AP2M1 8627
CAPZA2 8597
FNBP1L 8551
AMPH 8532
ARRB2 8490
RAB27A 8411
DCTN4 8387
CLTA 8376
COPA 8366
AP3B1 8365
RIN2 8355
CHMP3 8349
MARCO 8329
RAB1B 8313
KIF3C 8306
ARPC3 8277
HIP1 8258
KIF5B 8239
VAMP3 8222
KIF1B 8184
EGF 8179
REPS2 8154
RAB6A 8148
CAPZA1 8135
RAB3A 8133
PACSIN2 8123
SEC24D 8115
DAB2 8112
TBC1D10B 8078
EPN1 8045
MAP1LC3B 8043
TOR1A 8033
AP2S1 8026
CAPZB 8015
VPS37C 8010
GJD3 7996
TMED7 7950
RAB4A 7941
DENND3 7938
MAN1A1 7927
STX6 7906
GABARAP 7904
COPB2 7902
ARF5 7885
AP3S1 7874
ACTR2 7870
SNX2 7861
ACTR3 7818
FCHO2 7807
TRAPPC1 7806
RAB18 7801
KIF1C 7799
TSG101 7786
CNIH1 7779
DENND5A 7736
DYNC1I2 7735
ARF3 7732
KDELR2 7728
SEC24A 7660
VPS25 7638
SH3GL1 7625
ACTR10 7605
RIN1 7602
SPTA1 7595
COPG2 7594
VPS54 7568
ARPC4 7516
RHOQ 7511
COPG1 7509
CBL 7480
RABGEF1 7466
SNAPIN 7443
DENND1A 7441
NAA38 7435
STXBP3 7424
MVB12A 7400
ARPC2 7390
KLC3 7377
SPARC 7339
SEC23A 7335
COPB1 7321
DCTN6 7300
GDI2 7282
RAB33B 7267
AP2A2 7257
TMED9 7167
STX5 7166
TFG 7160
IGF2R 7149
ULK1 7125
TRAPPC3 7114
RAB39A 7113
RAB5A 7103
MCFD2 7099
RAB14 7095
LMAN2 7080
SURF4 7058
DNM3 7045
TBC1D1 7034
F8 7022
SNX18 7017
ACTR1A 7002
PAFAH1B2 6942
DYNC1LI1 6941
LMAN2L 6937
COPE 6896
AP2A1 6832
RIC1 6824
PPP6C 6819
BLOC1S6 6815
GAPVD1 6799
DNASE2 6745
TRAPPC8 6735
AP1M1 6711
MYO5A 6693
RAB5B 6690
MYH9 6685
UBB 6639
MAN2A2 6625
MON1B 6612
GORASP1 6606
GRK3 6593
COPS7A 6590
RAB8B 6529
GALNT1 6508
NEDD8 6482
SAR1B 6479
VPS37A 6467
TBC1D7 6452
OCRL 6442
RAB43 6433
AP4E1 6419
SNAP29 6390
YWHAB 6385
PREB 6368
CALR 6340
TRAPPC12 6310
COL7A1 6304
SYNJ1 6296
GOLGA2 6203
VTA1 6185
LDLR 6183
SH3KBP1 6173
RAB21 6165
STAM2 6159
COPS2 6139
DNM2 6089
CYTH4 6085
CLTB 6084
GRK2 6068
RAB6B 6053
TMED2 6052
COPS3 6005
KIF13B 5998
DCTN3 5994
AREG 5977
SNF8 5973
SCARB1 5962
DYNLL1 5952
UBQLN2 5939
CTTN 5930
DENND2C 5898
SEC22B 5873
CD59 5859
YIPF6 5857
ACBD3 5816
RAB3GAP1 5768
SEC13 5748
GDI1 5739
CHMP2B 5714
EXOC1 5670
RAB36 5636
YWHAZ 5624
HPS1 5605
EXOC4 5591
ARCN1 5580
MIA2 5574
STAB2 5569
KLC1 5523
KIF23 5510
TMEM115 5508
CHMP6 5499
PRKAG1 5476
PAFAH1B1 5470
TRAPPC9 5333
GOLGA5 5322
TRAPPC11 5319
VTI1A 5302
GOLIM4 5271
PPP6R1 5263
SCARB2 5255
VAMP8 5218
VPS4B 5212
YKT6 5205
TRAPPC5 5191
MVB12B 5175
UBQLN1 5108
KIF20A 5096
DCTN1 5078
ITSN2 5060
SYT1 5056
HBEGF 5013
CHMP5 4943
EXOC7 4924
FTH1 4902
AGPAT3 4809
GJB6 4761
EXOC3 4724
STX18 4648
DNAJC6 4640
SEC16A 4619
RGP1 4538
HGS 4513
UBC 4439
RABEPK 4434
USP6NL 4433
RAB3GAP2 4429
PAFAH1B3 4417
RAB11B 4402
COPS5 4361
DYNC1LI2 4273
COG7 4269
KIF9 4253
CCZ1 4242
VPS28 4199
DYNC1I1 4187
USO1 4154
TRAPPC6B 4147
EXOC5 4141
NAPG 4139
EPS15 4138
RAB9A 4088
COPZ1 4035
AP1G1 3987
RAB35 3981
VPS37B 3908
RAB8A 3880
GGA3 3816
CLINT1 3815
TBC1D13 3782
KIF3B 3740
STX16 3717
ARFGAP3 3714
ALB 3668
TBC1D15 3665
EPS15L1 3655
AKT1 3614
SEC24B 3608
DNM1 3587
KIF4A 3585
STON2 3569
SCFD1 3525
PIP5K1C 3419
TBC1D16 3409
NECAP2 3387
RAB27B 3386
MYO1C 3310
PPP6R3 3261
PUM1 3250
RAB3IP 3237
TBC1D24 3200
VAMP4 3191
ALS2 3176
KIAA0319 3163
DENND4B 3139
DENND6B 2993
RACGAP1 2848
KIF16B 2785
GCC1 2730
TMED3 2720
RALA 2710
EPGN 2662
STON1 2574
GAK 2570
KIF27 2549
TMF1 2535
VPS45 2496
COL1A2 2469
CFTR 2416
GOLGA1 2415
CHMP4A 2400
CSNK1D 2390
TRIP10 2343
CTSC 2326
GGA1 2310
CHM 2273
NECAP1 2220
HSP90B1 2059
RABGAP1 2052
PRKAG2 2015
ARRB1 1998
EREG 1888
AP1M2 1832
COPS4 1776
COPS6 1637
SFN 1615
TFRC 1524
NAPA 1432
TBC1D8B 1417
ARF6 1377
HSP90AA1 1326
LRP2 1307
PRKAB1 1302
STAM 1285
KIF6 1147
UBA52 1121
TF 1102
SEC31A 1099
GJC2 1083
DTNBP1 1014
CCZ1B 990
COL4A2 970
USE1 938
KIF11 787
VPS4A 784
MSR1 772
SCARF1 745
KIF2C 726
CNIH2 654
STX4 606
GJC1 518
SYT2 461
CYTH2 442
AKT2 433
TXNDC5 393
SYS1 386
IGHV1-2 360
CENPE 332
SEC16B 330
TMED10 323
WASL 299
AVPR2 291
IGHV2-5 230
APOE 218
NBAS 208
ANKRD27 186
AP4M1 138
IGHV3-53 103
ZW10 31
EXOC8 -1
COG4 -6
TBC1D20 -18
TBC1D3 -66
HYOU1 -113
KIF18B -143
GOSR1 -182
KIFC1 -249
FNBP1 -311
VPS53 -341
COG8 -346
SNX9 -430
IGHV3-7 -441
SEC23IP -468
DENND6A -562
TRIP11 -579
BET1 -594
IGHV1-46 -618
IGHV3-48 -668
IGKV3-11 -781
TSC2 -804
RAB12 -856
SCOC -885
IGKV1-39 -989
IGLV7-46 -1016
KIF2A -1069
SCGB3A2 -1154
IGKV1-5 -1184
HPX -1199
IGHA2 -1274
IGLV2-8 -1294
IGKV5-2 -1298
IGHV3-23 -1317
MAN2A1 -1349
IGHV3-13 -1443
GOSR2 -1456
CHML -1515
IGLV2-18 -1524
IGKV1-16 -1528
RAB7B -1531
IGLV4-69 -1559
IGKV1D-39 -1574
KIFC2 -1642
IGHV1-69 -1822
IGLV10-54 -1884
ARFGAP1 -1942
IGLV1-36 -2030
IGKV2-30 -2045
MAN1A2 -2055
CALM1 -2081
IGLV7-43 -2089
IGLV3-19 -2111
KDELR3 -2117
TSC1 -2118
IGHV3-11 -2134
TOR1B -2136
AP1S2 -2261
IGHA1 -2291
IGKV3-15 -2297
TRAPPC2L -2299
FCHO1 -2392
IGKV1-33 -2424
TRAPPC13 -2479
IGHV3-30 -2484
IGKV4-1 -2532
SEC24C -2569
AP2B1 -2709
KIF18A -2742
NAPB -2780
IGKV1-17 -2871
IGLV2-23 -2878
IGLV6-57 -2885
IGHV4-59 -2892
IGLV2-11 -2905
MON1A -2910
IGHV3-33 -2988
IGHV4-34 -3016
IGKV3-20 -3085
IGHV2-70 -3138
ARFIP2 -3197
KIF15 -3249
IGLV1-44 -3258
COG5 -3259
SNX5 -3305
SPTBN5 -3531
TPD52L1 -3542
VPS52 -3619
IGKV3D-20 -3894
RAB41 -3974
DYNLL2 -3980
SH3D19 -4011
GOLGA4 -4064
DCTN5 -4086
EPN2 -4100
RALGAPB -4138
IGLV3-1 -4159
JCHAIN -4240
SEC22C -4248
DENND5B -4249
GBF1 -4290
COLEC12 -4367
IGKC -4428
GPS1 -4517
IGHV4-39 -4582
IGLV3-21 -4735
IGLV1-40 -4788
ANK3 -4919
KIF26A -4925
IGLV3-25 -4933
GJA3 -4935
IGLV1-51 -4956
SEC22A -5052
ARL1 -5063
SPTBN2 -5129
ASPSCR1 -5154
PIK3C2A -5194
IGLC7 -5281
GOLGB1 -5370
CD4 -5406
COG3 -5426
IGLV8-61 -5427
IGKV1-12 -5446
IGLC3 -5477
IGLC2 -5510
AP1S3 -5522
DENND4A -5540
AP1G2 -5590
SSC5D -5595
IGKV2D-28 -5634
AP4S1 -5731
ARFGAP2 -5786
IGKV2-28 -5808
COG6 -5811
IGLV5-45 -5869
IGLV3-27 -5874
IGLV1-47 -6018
IGLC1 -6157
MIA3 -6245
ANKRD28 -6250
TJP1 -6374
RAB9B -6552
VPS51 -6584
GGA2 -6587
KIF21B -6702
TRAPPC4 -6712
SYT11 -6763
KIF28P -6770
MAN1C1 -6804
VPS36 -6848
RPS27A -6938
REPS1 -7137
AP4B1 -7235
YWHAQ -7340
IGLV3-12 -7358
BICD1 -7365
TBC1D25 -7372
DENND1C -7377
BET1L -7405
BLOC1S4 -7493
ARFRP1 -7561
C2CD5 -7570
DENND4C -7574
BNIP1 -7588
APOL1 -7657
DYNC1H1 -7685
GCC2 -7725
SPTBN1 -7764
EXOC2 -7780
KIF20B -7822
COG2 -7917
PRKAB2 -8172
CYTH3 -8200
ALS2CL -8315
IGLV2-14 -8345
DENND2A -8355
KLC4 -8376
SYNJ2 -8511
M6PR -8519
KIFAP3 -8619
BLOC1S3 -8703
TRAPPC2 -8704
RAB38 -8714
TBC1D17 -8716
COPS8 -8755
CHMP7 -8802
SRC -8820
KIF5C -8865
KIF5A -8869
CNIH3 -9011
KLC2 -9059
AAK1 -9190
DENND1B -9284
LDLRAP1 -9326
TRAPPC10 -9369
HSPH1 -9407
LNPEP -9618
TPD52 -9644
NAA30 -9696
COPS7B -9775
RAB30 -9844
POLG -9889
SYTL1 -10104
RINT1 -10112
RINL -10326
SBF1 -10530
IL7R -10546
HIP1R -10615
LMAN1 -10630
TBC1D4 -10754
COPZ2 -10863
TRAPPC6A -10917
HSPA8 -10922
RAB33A -10940
STX17 -11006
DVL2 -11152
RHOBTB3 -11172
CD3D -11401
MYO6 -11410
BIN1 -11411
SPTAN1 -11426
NAA35 -11524
CD3G -11526
RAB39B -11529
HPS4 -11558
FZD4 -11650
KIF26B -11663
KIF19 -11733
SLC2A8 -11749
RABEP1 -11754
OPTN -11766
VAMP2 -11779
KIF21A -11837
AKT3 -11849
TBC1D10C -11861
ADRB2 -11892
MADD -11899
KIF3A -11972
TBC1D10A -12025
SCARA5 -12055
PLA2G6 -12122
COG1 -12125
DENND2D -12293
CYTH1 -12314
KIF22 -12358
PACSIN1 -12374


Signal Transduction

Signal Transduction
1069
set Signal Transduction
setSize 1894
pANOVA 7.04e-28
s.dist 0.152
p.adjustANOVA 1.6e-25



Top enriched genes

Top 20 genes
GeneID Gene Rank
CSF2RA 9526
PPARG 9522
WASF1 9520
S100A9 9516
FZD5 9513
EDNRB 9512
S100A8 9503
PLB1 9490
SOCS3 9476
GPER1 9475
XK 9468
HRH2 9466
GNA15 9452
CCR2 9449
GRB10 9439
CTSD 9433
PRKACA 9429
ATP6V0A1 9423
NUMB 9414
LAMTOR1 9411

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CSF2RA 9526.0
PPARG 9522.0
WASF1 9520.0
S100A9 9516.0
FZD5 9513.0
EDNRB 9512.0
S100A8 9503.0
PLB1 9490.0
SOCS3 9476.0
GPER1 9475.0
XK 9468.0
HRH2 9466.0
GNA15 9452.0
CCR2 9449.0
GRB10 9439.0
CTSD 9433.0
PRKACA 9429.0
ATP6V0A1 9423.0
NUMB 9414.0
LAMTOR1 9411.0
LAMC1 9387.0
ADM 9378.0
H2AJ 9374.0
RHOT1 9367.0
MYO7A 9361.0
RASGRP4 9359.0
PTAFR 9355.0
GNG10 9349.0
CTNNA1 9341.0
GPR27 9340.0
TACC3 9331.0
SNX3 9326.0
ARHGEF11 9305.0
GRB2 9304.0
ATP6V1A 9302.0
FPR1 9295.0
FSTL3 9290.0
ITSN1 9289.0
H2BC21 9283.0
DUSP3 9280.0
TNFRSF1A 9270.0
NCF4 9268.0
CYFIP1 9265.0
YWHAG 9264.0
TNS3 9262.0
ARPC1B 9259.0
ATP6V0D1 9245.0
FES 9237.0
WNT11 9215.0
NCF2 9190.0
UBE2D1 9187.0
NCSTN 9186.0
PLA2G4A 9180.0
APP 9177.0
RTN4 9159.0
SPTB 9154.0
KREMEN1 9149.0
CD55 9145.0
ACVR1B 9135.0
GPR84 9133.0
C5AR1 9129.0
ATP6V0C 9127.0
RIT1 9121.0
MAPK14 9104.0
FRAT2 9096.0
FPR2 9095.0
FKBP5 9091.0
LRP1 9080.0
SYK 9076.0
FURIN 9075.0
RCOR1 9073.0
TNFRSF10D 9072.0
AGO4 9070.0
MAP2K1 9063.0
ATP6V1B2 9057.0
FKBP1A 9056.0
H2BC12 9051.0
ATP6V1D 9047.0
YWHAE 9045.0
PHC2 9043.0
PIK3CB 9038.0
VAPA 9033.0
CYBB 9031.0
CARM1 9020.0
ACTB 9011.0
PRKCD 9008.0
DLG4 9007.0
CLTC 9000.0
STK3 8995.0
GNAQ 8993.0
ADCY3 8984.0
KL 8963.0
HDAC4 8960.0
MAML3 8957.0
MAPK3 8953.0
FGD4 8948.0
PLCB3 8916.0
ALDH1A2 8914.0
CRK 8906.0
OS9 8898.0
ARPC1A 8894.0
ITGA2B 8893.0
TGFA 8889.0
CDC42EP3 8880.0
ZDHHC9 8872.0
PLPPR2 8868.0
CCR1 8865.0
HGF 8863.0
ARHGAP18 8852.0
MEMO1 8847.0
CDKN2B 8836.0
MKRN1 8817.0
GNG5 8815.0
PROK2 8806.0
NTSR1 8805.0
RHOU 8794.0
RAC1 8793.0
ADAM10 8791.0
FOSL1 8788.0
LTB4R 8787.0
STRADB 8773.0
RBPJ 8770.0
RRAGD 8753.0
APBB1IP 8744.0
JAG1 8743.0
PCSK6 8740.0
ARHGEF40 8723.0
SUFU 8718.0
ADGRE1 8715.0
FRAT1 8712.0
BCL2L1 8700.0
MARK3 8697.0
RNF146 8696.0
ARPC5 8686.0
FOXO3 8682.0
H3-3A 8661.0
YWHAH 8649.0
SNAI1 8645.0
UBE2D3 8640.0
ARHGDIB 8639.0
ZDHHC7 8636.0
IQCE 8634.0
AP2M1 8627.0
CDK5 8616.0
CDH5 8613.0
PRKAR1A 8607.0
ATP6V0B 8598.0
ATP6V0E1 8596.0
MYL6 8576.0
IRS2 8569.0
ACTG1 8562.0
WAS 8560.0
TLE3 8558.0
SOCS6 8557.0
CLIP1 8540.0
ATP6V1C1 8539.0
TLN1 8525.0
DIAPH2 8523.0
ACVRL1 8519.0
SMAD1 8511.0
LAMTOR5 8498.0
F2RL1 8495.0
ARRB2 8490.0
DLC1 8488.0
RHOG 8487.0
PSMB7 8485.0
OR2W3 8484.0
TFDP1 8470.0
PTEN 8460.0
SPINT1 8446.0
P4HB 8440.0
ADORA2B 8437.0
RALB 8414.0
BAMBI 8405.0
PSMD4 8402.0
RNF41 8389.0
PTGFR 8385.0
SPOPL 8384.0
MAPKAPK3 8382.0
CLTA 8376.0
REEP4 8375.0
WASF2 8369.0
ARHGAP26 8368.0
MRTFA 8350.0
BAG4 8328.0
TNFRSF10B 8321.0
RHOA 8319.0
SOS2 8299.0
GNB1 8294.0
ITGB3 8291.0
FN1 8284.0
INSR 8282.0
ARPC3 8277.0
CAB39 8276.0
OMG 8272.0
ECE1 8271.0
TAX1BP3 8262.0
PSME3 8251.0
MOB1A 8240.0
KIF5B 8239.0
PPP2CA 8234.0
HEBP1 8232.0
PAK1 8230.0
ARAP3 8225.0
LYL1 8221.0
JAK3 8219.0
SPINT2 8206.0
PPM1A 8200.0
SP1 8193.0
C5AR2 8187.0
CFL1 8186.0
PAK2 8185.0
EGF 8179.0
PPP3R1 8175.0
MKNK1 8170.0
B9D2 8168.0
ATP6AP1 8160.0
IQGAP1 8152.0
PTPN12 8151.0
RAB6A 8148.0
LYPLA1 8143.0
TRIM27 8142.0
GNB2 8141.0
MYD88 8136.0
IL6R 8132.0
CAMKK2 8125.0
ADAM17 8110.0
WLS 8104.0
PSMB5 8101.0
GAB2 8099.0
STAT3 8098.0
ARHGAP29 8084.0
GNAI2 8075.0
LIMK2 8074.0
ATP6V1H 8064.0
F11R 8058.0
EPN1 8045.0
ATP2A2 8038.0
ATP6V1E1 8035.0
EIF4G1 8031.0
AP2S1 8026.0
DOK1 8022.0
P2RY13 8016.0
WWP2 8013.0
C3AR1 8012.0
MEF2A 8009.0
H2BC5 8003.0
REEP5 7989.0
NCOR2 7985.0
CHUK 7966.0
PSEN1 7961.0
DGKG 7958.0
GNAI3 7953.0
RHOBTB1 7943.0
RAB4A 7941.0
PTK2B 7935.0
H2AC6 7934.0
PRKAR1B 7918.0
H2BC11 7912.0
KDM4B 7911.0
GNAS 7909.0
FSTL1 7908.0
MAPK6 7903.0
NOTCH3 7899.0
VAV1 7896.0
TBL1X 7887.0
EPAS1 7886.0
RAF1 7879.0
NEDD4L 7875.0
ACTR2 7870.0
OPRL1 7866.0
AKT1S1 7865.0
GMIP 7856.0
P2RY1 7852.0
PSMD6 7846.0
ANXA1 7842.0
SMAD6 7835.0
ACTR3 7818.0
ARAP1 7817.0
USP4 7812.0
PIK3AP1 7811.0
LYN 7809.0
PTPRJ 7783.0
CSNK1A1 7766.0
GSK3A 7760.0
ARHGAP19 7756.0
DYNC1I2 7735.0
RGS19 7734.0
PPP2CB 7712.0
MYL9 7703.0
RPS6KA1 7695.0
MGLL 7694.0
BEX3 7689.0
CASP9 7685.0
NCKAP1L 7673.0
RHEB 7669.0
CSF2RB 7661.0
MAPRE1 7658.0
SPHK1 7657.0
LRRK2 7654.0
ZFYVE16 7649.0
RGL1 7647.0
TRIB1 7643.0
NDEL1 7627.0
MAP3K11 7626.0
SH3GL1 7625.0
TFF3 7621.0
PSMD9 7620.0
PTPN2 7615.0
CFLAR 7610.0
SH2B2 7609.0
SPTA1 7595.0
RGS2 7577.0
LAMTOR3 7574.0
CTNNBIP1 7569.0
LAMTOR2 7567.0
POLR2E 7563.0
ADAP1 7557.0
TEC 7549.0
CDC42 7537.0
RUNX1 7529.0
ARHGAP24 7523.0
RGL2 7520.0
ARPC4 7516.0
RHOQ 7511.0
PTCRA 7507.0
LAMB3 7497.0
RXRA 7495.0
MAPK1 7493.0
ROCK1 7489.0
CCND3 7487.0
SERPINE1 7483.0
CBL 7480.0
UBE2M 7477.0
PLXND1 7475.0
VEGFA 7467.0
IER3 7463.0
NCKAP1 7462.0
HIF1A 7436.0
ARHGAP6 7433.0
KLHL12 7429.0
NR1H2 7415.0
PSMD2 7411.0
PLEKHG2 7395.0
FAM13A 7392.0
ARPC2 7390.0
H2BC4 7389.0
BCL2L11 7384.0
KLC3 7377.0
CXCL16 7375.0
FRS3 7343.0
SPARC 7339.0
PLTP 7338.0
GNB4 7336.0
NCF1 7334.0
SHOC2 7333.0
PSMA1 7329.0
VCL 7328.0
DOCK1 7314.0
RAP1A 7305.0
DLD 7303.0
H2BC17 7285.0
GDI2 7282.0
PIK3R6 7270.0
AP2A2 7257.0
SPPL2A 7250.0
PSMD1 7241.0
ADGRE2 7236.0
RFNG 7233.0
OXER1 7229.0
EPOR 7223.0
MOB1B 7207.0
BTK 7206.0
FLT3 7196.0
FFAR2 7193.0
RXFP2 7189.0
TCIRG1 7188.0
PSMB3 7171.0
IL1RAP 7150.0
PSAP 7145.0
PRKCB 7097.0
PSMA7 7096.0
TYK2 7087.0
ABI1 7082.0
SRF 7079.0
CCRL2 7073.0
LRP10 7070.0
KIDINS220 7069.0
GTF2A2 7066.0
PPP1CB 7064.0
DNM3 7045.0
PARD3 7040.0
THBS3 7037.0
BRK1 7032.0
PSMC1 7021.0
REEP3 7016.0
PPP3CB 7005.0
GPR35 6986.0
TMED5 6984.0
RGS18 6972.0
STAT5A 6965.0
TAB2 6964.0
DUSP1 6950.0
RGS14 6948.0
DYNC1LI1 6941.0
SPRED2 6936.0
STAT5B 6925.0
CYBA 6922.0
GPSM3 6912.0
VEGFC 6906.0
PRKG1 6901.0
BAD 6892.0
VCP 6886.0
RAPGEF2 6867.0
CXCR1 6864.0
TLE4 6854.0
ARHGEF17 6852.0
SEL1L 6847.0
PPP1R14A 6839.0
AP2A1 6832.0
CUL3 6821.0
PSMB6 6813.0
WASF3 6808.0
NFKBIA 6807.0
JUNB 6806.0
STRAP 6805.0
RALBP1 6796.0
MAP2K2 6794.0
FLT1 6793.0
NLN 6785.0
PPP2R5B 6774.0
DTX2 6754.0
SRGAP1 6744.0
PRKAR2B 6741.0
GFAP 6713.0
ST3GAL6 6701.0
H3C15 6699.5
MYH9 6685.0
GNAT2 6683.0
POLR2J 6671.0
VPS35 6668.0
PSMF1 6659.0
E2F3 6650.0
VWF 6641.0
UBB 6639.0
SDC4 6637.0
PSMC6 6635.0
GSK3B 6634.0
VPS26A 6632.0
MYLK 6618.0
IQGAP2 6599.0
RGS16 6598.0
INSL3 6594.0
GRK3 6593.0
GRK6 6587.0
PSMD12 6556.0
ARHGEF2 6546.0
SREBF1 6539.0
GNG11 6495.0
LEPR 6485.0
NEDD8 6482.0
RDH11 6466.0
FZD2 6462.0
AHCYL1 6456.0
FFAR3 6455.0
PIP5K1B 6450.0
OCRL 6442.0
USF2 6440.0
RARA 6429.0
MYO9B 6424.0
USP8 6418.0
PREX1 6414.0
CTNNB1 6408.0
FOXO4 6391.0
CSNK2A2 6388.0
YWHAB 6385.0
KBTBD7 6376.0
PDE3A 6353.0
E2F1 6343.0
PPP1CC 6330.0
USP7 6323.0
LRP12 6321.0
CAMKK1 6317.0
OR52K1 6313.0
E2F4 6300.0
APH1B 6280.0
NFKB1 6277.0
ABR 6260.0
ELMO1 6258.0
ARHGAP9 6256.0
EEPD1 6251.0
RRAGA 6244.0
DHRS9 6236.0
PSMD11 6231.0
PXN 6230.0
PPP3CA 6217.0
SIRT6 6214.0
NEDD4 6201.0
CSNK2A1 6199.0
LDLR 6183.0
SH3KBP1 6173.0
SRGAP2 6171.0
PRKAR2A 6166.0
STAM2 6159.0
DTX4 6156.0
RGL3 6150.0
PTPN18 6149.0
USP15 6148.0
ROCK2 6138.0
PDPK1 6136.0
IRAK1 6131.0
EP300 6129.0
LATS2 6128.0
HDAC7 6122.0
PIP5K1A 6110.0
ABCA1 6109.0
ITGAV 6106.0
ARHGDIA 6104.0
ARHGEF37 6100.0
PTPN6 6096.0
DNM2 6089.0
RGS6 6086.0
CLTB 6084.0
FNTB 6081.0
EIF4EBP1 6072.0
GRK2 6068.0
TMED2 6052.0
PPP1R12A 6050.0
PIK3CD 6046.0
PPBP 6042.0
H2AZ1 6036.0
RLN3 6033.0
LPAR2 6032.0
TAX1BP1 6031.0
SHB 6026.0
FABP5 6021.0
ASH2L 6001.0
IGF1R 5990.0
PDGFC 5986.0
PPP1R15A 5981.0
AREG 5977.0
PSMA6 5970.0
LAMB1 5966.0
P2RY2 5965.0
PSMD7 5963.0
AMOTL1 5960.0
PTK6 5956.0
PDK4 5953.0
DYNLL1 5952.0
THBS1 5951.0
PSMD13 5948.0
OPN3 5942.0
CTTN 5930.0
BAX 5916.0
SUCNR1 5905.0
SHARPIN 5902.0
PPP2R5A 5897.0
NCOR1 5887.0
STAT6 5884.0
ADM2 5881.0
APOA2 5879.0
ATP6V1F 5878.0
PDE1B 5874.0
CXCR2 5861.0
PDGFRA 5858.0
ITPR2 5842.0
GRIN2D 5841.0
GNA13 5836.0
ARHGAP27 5830.0
CXCL1 5824.0
DAGLB 5820.0
RANBP9 5813.0
ADORA3 5799.0
ST3GAL4 5781.0
KEL 5775.0
OR2L2 5770.0
PSMD8 5757.0
RNF111 5749.0
SEC13 5748.0
PDE4C 5741.0
GDI1 5739.0
PSENEN 5735.0
CDC42EP2 5731.0
ATP6V1E2 5730.0
MAF1 5723.0
PTPN1 5722.0
WIPF2 5713.0
PF4 5707.0
ATF1 5706.0
LPAR1 5694.0
TAB1 5681.0
GAB1 5679.0
SOX6 5665.0
DVL3 5656.0
AGO1 5654.0
FADD 5641.0
PLXNB1 5639.0
YWHAZ 5624.0
ARHGAP23 5618.0
ECT2 5570.0
KLC1 5523.0
ARHGAP31 5501.0
HDAC2 5482.0
PRKAG1 5476.0
PAFAH1B1 5470.0
USP9X 5464.0
OR2B11 5463.0
FOS 5460.0
PFN1 5459.0
CBX8 5448.0
GTF2F2 5434.0
OR2T33 5429.0
TAOK1 5420.0
CXCL2 5412.0
NSL1 5408.0
MAML1 5404.0
SDC2 5397.0
H2BC9 5394.0
BRAP 5387.0
IKBKG 5377.0
NRAS 5363.0
PSMA2 5339.0
S1PR3 5323.0
PTPN11 5314.0
H2BC15 5312.0
POLR2L 5305.0
STAG2 5301.0
PDGFA 5293.0
NOTCH2 5272.0
ADCY4 5270.0
PAG1 5268.0
PDE6D 5250.0
CALCRL 5232.0
CSK 5219.0
SNW1 5201.0
HNRNPM 5195.0
RAC2 5163.0
TGFB1 5153.0
TBXA2R 5148.0
GPR37L1 5140.0
COL9A3 5126.0
PBX1 5098.0
MYL12B 5088.0
CPT1A 5077.0
KDM1B 5073.0
MAPKAP1 5057.0
COL6A3 5053.0
ARHGAP30 5039.0
ARHGAP21 5032.0
CDC73 5020.0
HBEGF 5013.0
PIK3R2 5010.0
PLCG2 5006.0
H2AC20 4972.0
CDC25C 4969.0
RRAGC 4954.0
GTF2F1 4951.0
CHN2 4938.0
NCK2 4934.0
ID1 4927.0
SMAD2 4905.0
VAV3 4894.0
WNT6 4864.0
PCSK5 4863.0
CXCL3 4851.0
SOX4 4850.0
AR 4840.0
USF1 4829.0
P2RY12 4821.0
EIF4E 4813.0
CNR1 4795.0
F2RL3 4773.0
HDAC11 4756.0
SMARCA4 4733.0
HDAC5 4710.0
NOTCH1 4704.0
PPID 4695.0
BIRC2 4692.0
GRAP2 4690.0
LIMK1 4679.0
HDAC3 4673.0
PLCB2 4665.0
GPSM2 4658.0
RGS10 4637.0
PIK3CA 4629.0
IFT122 4625.0
PSMD3 4618.0
ARHGAP1 4613.0
NRIP1 4609.0
POLR2F 4604.0
SGK1 4595.0
PPP2R1A 4589.0
FGD2 4576.0
LRP8 4568.0
TBL1XR1 4556.0
CAV2 4516.0
HGS 4513.0
CDKN1A 4511.0
GAS8 4496.0
FZD1 4492.0
NCOA1 4483.0
HCAR2 4477.0
PTK2 4462.0
LAMTOR4 4441.0
UBC 4439.0
AATF 4427.0
S1PR4 4425.0
OR6C75 4424.0
ELMO2 4397.0
DIAPH3 4379.0
KCTD6 4371.0
PTGER3 4360.0
DUSP6 4357.0
SEM1 4348.0
NMT1 4328.0
MDM2 4312.0
GNG8 4296.0
B4GALT1 4292.0
LRP5 4289.0
SKP1 4287.0
PDHX 4282.0
DYNC1LI2 4273.0
PDK1 4249.0
PDHB 4233.0
GPR65 4232.0
DYNC1I1 4187.0
SHC2 4183.0
ITGA2 4168.0
KSR1 4167.0
CRHBP 4166.0
CENPA 4162.0
SHC1 4161.0
FMNL1 4150.0
TJP2 4142.0
EPS15 4138.0
APH1A 4133.0
PTGES3 4125.0
CDC37 4096.0
PSMB2 4084.0
SQSTM1 4081.0
CTBP2 4080.0
PPP1CA 4069.0
GOLGA7 4055.0
MAPKAPK2 4054.0
RCVRN 4036.0
CBX6 4033.0
SCD 4026.0
IL6ST 4025.0
CDC20 3998.0
SHC3 3974.0
CSNK2B 3969.0
CRKL 3966.0
C5 3954.0
SOCS1 3947.0
MAP2K5 3940.0
RBX1 3934.0
ATP6V1G1 3931.0
HNRNPF 3929.0
FGF2 3920.0
MMP7 3918.0
TGFBR2 3914.0
STARD8 3913.0
SH2B3 3910.0
CXCL5 3899.0
MAPK13 3865.0
MAPK11 3826.0
ANOS1 3822.0
GGA3 3816.0
DHRS4 3786.0
OR2V2 3755.0
NRG1 3750.0
BIRC5 3738.0
ZRANB1 3730.0
JUN 3722.0
WDR83 3718.0
FAS 3712.0
KRAS 3702.0
STRN 3695.0
PHLPP1 3658.0
EPS15L1 3655.0
HSD17B1 3654.0
AKT1 3614.0
CGN 3591.0
DNM1 3587.0
NPFFR1 3564.0
NCOA3 3522.0
RNF2 3513.0
POLR2G 3508.0
DAAM1 3466.0
OR10G3 3447.0
RGR 3440.0
BMPR2 3427.0
PSMD5 3426.0
CREBBP 3423.0
PIP5K1C 3419.0
OR2C3 3415.0
FFAR4 3410.0
FGD3 3408.0
NLK 3405.0
RLBP1 3401.0
DNAL4 3398.0
AKAP13 3393.0
PSMB1 3374.0
IQGAP3 3370.0
GNA12 3367.0
PMF1 3364.0
KTN1 3363.0
BUB1 3362.0
KIF14 3352.0
PDE11A 3331.0
GNAI1 3329.0
ADORA2A 3293.0
OR8A1 3283.0
GNA11 3259.0
PDK3 3252.0
APC 3240.0
ZNF217 3232.0
INHBA 3227.0
RAP1B 3206.0
KMT2D 3203.0
IL1RL1 3175.0
ARHGEF12 3166.0
TAB3 3160.0
VPS29 3151.0
RAB4B 3137.0
RGS17 3134.0
EGR1 3124.0
DLGAP5 3106.0
NUP98 3101.0
YBX1 3097.0
TNFSF10 3093.0
AVPR1A 3091.0
RPS6KA2 3087.0
HDAC8 3079.0
STARD13 3078.0
GATAD2A 3075.0
NUP37 3074.0
NTRK3 3068.0
ABCG8 3056.0
DERL2 3041.0
NF1 3036.0
KLK2 3029.0
CETP 3003.0
PLK1 3002.0
BUB1B 2997.0
AGO2 2995.0
GLI1 2991.0
RPS6KA3 2973.0
PSPN 2969.0
MTMR4 2951.0
GNAZ 2909.0
LGR4 2883.0
CCNK 2877.0
KHDRBS1 2861.0
POMC 2855.0
RAMP3 2854.0
RACGAP1 2848.0
ARHGAP28 2835.0
OR7D4 2812.0
SLC38A9 2807.0
OR2G6 2743.0
CENPF 2723.0
GTF2A1 2713.0
RALA 2710.0
JAK2 2691.0
EPGN 2662.0
SKA1 2649.0
ARAF 2644.0
ARHGAP32 2642.0
HPN 2625.0
PSMD14 2611.0
SDC3 2599.0
PSMC2 2598.0
NDE1 2594.0
ANGPT1 2562.0
RANBP10 2553.0
LPL 2545.0
PLPPR3 2540.0
PSMB4 2523.0
PTPRO 2501.0
SMPD2 2476.0
OR52A1 2461.0
ARHGEF6 2453.0
OR51L1 2440.0
PPP2R5D 2421.0
CFTR 2416.0
OR2H2 2406.0
MAP3K7 2395.0
GREM2 2392.0
GRPR 2385.0
OR7C1 2378.0
OR2M4 2367.0
TRIP10 2343.0
STRADA 2330.0
SPC24 2306.0
MYC 2304.0
SPRY1 2302.0
STK11 2289.0
PRICKLE1 2283.0
HDAC10 2280.0
ADRA2A 2271.0
SFPQ 2253.0
CBX4 2222.0
RBCK1 2214.0
OPRM1 2161.0
CCR9 2157.0
GRK4 2147.0
MT-RNR2 2112.0
RASA1 2106.0
ATF2 2085.0
CBFB 2078.0
POFUT1 2056.0
TSHR 2051.0
MCF2 2018.0
PRKAG2 2015.0
ARRB1 1998.0
WNT9B 1992.0
PSMC3 1976.0
CAV1 1969.0
HCAR3 1965.0
CAMK2G 1921.0
EREG 1888.0
CCNC 1877.0
HSPB1 1863.0
ACKR2 1860.0
PIK3CG 1833.0
CNGB1 1822.0
TRIO 1820.0
TNFRSF10A 1815.0
GALNT3 1805.0
PPP1R12B 1775.0
DEPDC1B 1774.0
FER 1761.0
OR2M3 1744.0
IRS1 1741.0
CXCL8 1729.0
RAD21 1709.0
MMP9 1690.0
MECOM 1687.0
CDC14B 1678.0
OR5AU1 1664.0
ARHGAP11A 1642.0
PIK3C3 1619.0
POLR2C 1616.0
SFN 1615.0
RGS3 1612.0
NPHP4 1607.0
ARHGAP22 1595.0
TGFBR1 1585.0
PSMD10 1559.0
JUND 1549.0
CDK1 1540.0
POU2F1 1537.0
PTGER2 1463.0
QRFP 1452.0
OR1D2 1418.0
XIAP 1407.0
ARF6 1377.0
FOSB 1368.0
TACR2 1363.0
HDAC9 1359.0
NAB1 1342.0
TERT 1341.0
HSP90AA1 1326.0
PRKAA1 1322.0
ITCH 1318.0
KAT5 1314.0
BRAF 1308.0
LRP2 1307.0
PRKAB1 1302.0
STAM 1285.0
VRK3 1281.0
SSTR2 1275.0
RHOB 1254.0
DACT1 1252.0
EIF4B 1247.0
OR14L1P 1243.0
PDE4D 1217.0
OR56A1 1212.0
ARHGAP4 1204.0
PLCB1 1197.0
WWC1 1180.0
SPOP 1151.0
OR1I1 1136.0
PRKCA 1132.0
UBA52 1121.0
TF 1102.0
NCOA2 1092.0
ELK1 1040.0
RBBP5 1037.0
RIPK2 1025.0
SAG 998.0
GABRG2 996.0
SYVN1 992.0
PRC1 980.0
COL4A2 970.0
GNG3 890.0
CSNK1G2 887.0
GNAT1 877.0
REST 865.0
MST1 849.0
AURKB 846.0
CUL5 834.0
FKBP4 832.0
ELF3 828.0
FUZ 803.0
EVC 780.0
KIF2C 726.0
DEPDC7 725.0
RPS6KB2 700.0
ERLEC1 698.0
SAV1 679.0
MYH10 653.0
TIAM1 651.0
SMC1A 613.0
CHD8 604.0
RDH5 591.0
HDAC1 587.0
LRP6 577.0
WIPF1 569.0
CAMKMT 550.0
YY1 537.0
GNB5 512.0
NR3C1 511.0
ST3GAL3 505.0
LAMB2 501.0
RETSAT 498.0
FLNA 483.0
AKR1C1 473.0
IL33 445.0
TAS2R14 440.0
AKT2 433.0
APOM 429.0
ADGRE3 408.0
POLR2I 396.0
LTB4R2 384.0
MLST8 376.0
NELFB 374.0
CENPE 332.0
NCKIPSD 328.0
KREMEN2 316.0
MYB 302.0
WASL 299.0
AVPR2 291.0
TCF7L1 275.0
ARHGAP15 272.0
ATN1 234.0
ABL1 226.0
APOE 218.0
ADCY9 123.0
GALR1 122.0
RACK1 119.0
KISS1R 107.0
TNS4 100.0
PKN2 98.0
RASAL2 79.0
CHD1 69.0
EGR3 44.0
LEO1 39.0
ZW10 31.0
CENPN 20.0
DVL1 0.0
CD86 -14.0
KDM4A -20.0
FRK -24.0
ABHD17B -35.0
CXCR4 -45.0
HCAR1 -49.0
WNT5B -61.0
PTPN3 -85.0
ITGB1 -94.0
PRKCI -138.0
OR10AC1 -155.0
PTBP1 -205.0
BAIAP2 -215.0
STK4 -220.0
TRAF6 -229.0
PARD6A -239.0
PPP2R1B -241.0
OR2AT4 -242.0
MEF2C -293.0
OR4K17 -339.0
METAP2 -343.0
ERCC6L -415.0
APOD -426.0
ACTA2 -429.0
GPR132 -446.0
ERBB3 -472.0
ARHGAP44 -483.0
TNKS2 -499.0
DGKD -501.0
CAB39L -519.0
MBD3 -528.0
TRADD -556.0
ARL2 -565.0
ERBIN -574.0
KNL1 -581.0
MAML2 -582.0
CLASP1 -588.0
PSMA4 -616.0
CASP3 -632.0
OR4D9 -638.0
GPNMB -672.0
PPP2R5E -680.0
OTULIN -683.0
FASN -690.0
NBEA -703.0
NUDC -709.0
RRAGB -713.0
SKIL -725.0
GPR83 -743.0
XCR1 -749.0
ICMT -786.0
OXTR -791.0
TSC2 -804.0
PDE2A -808.0
CCR10 -810.0
RANBP2 -820.0
SYDE2 -845.0
DIAPH1 -854.0
PSMC5 -863.0
CORT -886.0
GPS2 -889.0
ATP2A3 -914.0
GRK5 -919.0
USP34 -944.0
OR7G2 -970.0
AGO3 -1011.0
STUB1 -1032.0
LAMA1 -1044.0
RASAL1 -1060.0
PPEF1 -1061.0
KIF2A -1069.0
MAPK12 -1074.0
CDK5R1 -1089.0
OPHN1 -1158.0
NMB -1160.0
XPO1 -1185.0
PDE6G -1189.0
BCL9 -1190.0
REEP1 -1191.0
H2AZ2 -1209.0
TAS1R3 -1224.0
GRM6 -1228.0
TCF12 -1233.0
PLAT -1242.0
OR5A1 -1282.0
NSMAF -1303.0
MAPK7 -1337.0
CREB1 -1378.0
OR10A6 -1385.0
EGR2 -1435.0
CRABP2 -1447.0
OR7D2 -1582.0
SEPTIN7 -1594.0
IFT52 -1596.0
COL6A1 -1605.0
ADCY6 -1608.0
AHCTF1 -1644.0
DUSP10 -1650.0
SRMS -1710.0
PCP2 -1714.0
GATAD2B -1759.0
POLR2K -1783.0
RELA -1803.0
IFT57 -1811.0
LATS1 -1825.0
CDCA8 -1838.0
PDE7B -1841.0
RBBP4 -1870.0
NRG4 -1875.0
TRPC6 -1935.0
ZNRF3 -1963.0
LRRC7 -1966.0
CDK8 -1971.0
SMC3 -1975.0
PLG -1977.0
GABRB3 -1992.0
LAMC3 -2016.0
ABHD17C -2037.0
NOS3 -2059.0
CALM1 -2081.0
TSC1 -2118.0
OR10H5 -2146.0
CLASP2 -2151.0
GNG4 -2154.0
IFT88 -2201.0
PDE6A -2204.0
PKN1 -2208.0
ATP6V1C2 -2219.0
LAMA4 -2252.0
OR7A5 -2276.0
TIAL1 -2282.0
F2RL2 -2284.0
PIK3R5 -2304.0
PFN2 -2339.0
GABBR1 -2363.0
PIP4K2A -2365.0
DOCK7 -2369.0
ROR1 -2376.0
GNB3 -2397.0
SUZ12 -2409.0
KAT2B -2414.0
HTR7 -2438.0
CASP2 -2471.0
CHEK1 -2481.0
POLR2B -2523.0
ADGRE5 -2571.0
NEURL1B -2586.0
SMURF1 -2591.0
SOX7 -2675.0
AP2B1 -2709.0
OR1C1 -2716.0
PTPRU -2724.0
KIF18A -2742.0
OR1M1 -2746.0
RXFP4 -2801.0
ABHD6 -2829.0
WNT8B -2841.0
SCRIB -2849.0
OR4E1 -2862.0
ADCY2 -2896.0
RAPGEF3 -2911.0
OR6Y1 -2926.0
POLR2H -2942.0
PHB -2995.0
MIB1 -2998.0
MTA1 -3005.0
CCL3 -3027.0
NUP85 -3049.0
PSMB8 -3076.0
POLR2A -3092.0
MEF2D -3094.0
CENPI -3162.0
DGKH -3178.0
PIN1 -3188.0
DUSP7 -3211.0
OR7A17 -3221.0
RAC3 -3262.0
LAMA5 -3263.0
OR1A1 -3272.0
RXRB -3276.0
ADCY7 -3286.0
FGFR4 -3293.0
NGFR -3331.0
DTX1 -3340.0
ARHGAP35 -3359.0
KSR2 -3361.0
HRAS -3382.0
ETV4 -3386.0
FRS2 -3433.0
CASP10 -3446.0
SGO2 -3480.0
RPS6KB1 -3493.0
PDE4A -3520.0
MYH11 -3522.0
DLAT -3526.0
SPTBN5 -3531.0
OR2A5 -3544.0
LPAR6 -3569.0
UTS2 -3581.0
NR1H3 -3597.0
AAMP -3636.0
FLRT2 -3656.0
KALRN -3692.0
MDK -3714.0
LIN7B -3725.0
COL4A4 -3759.0
TAS2R30 -3784.0
PLIN1 -3785.0
PKN3 -3793.0
DAB2IP -3826.0
TCF4 -3836.0
CD19 -3843.0
ARHGEF4 -3861.0
PAQR3 -3864.0
UHMK1 -3877.0
COL4A3 -3896.0
LINC01139 -3904.0
ARHGEF38 -3906.0
CDK9 -3927.0
WNT2B -3938.0
OR6K3 -3942.0
PMEPA1 -3963.0
KANK1 -3964.0
ARHGEF26 -3971.0
DYNLL2 -3980.0
MYLIP -3991.0
ARHGEF10 -4015.0
POLR2D -4024.0
MED1 -4036.0
VAV2 -4055.0
INTU -4059.0
PIK3R4 -4062.0
RING1 -4063.0
OR5AN1 -4095.0
RASGRF1 -4123.0
PAK3 -4184.0
FCER2 -4230.0
FGF7 -4247.0
UCN -4278.0
GPC2 -4280.0
NRP2 -4282.0
NUF2 -4301.0
RASA2 -4320.0
TAS2R20 -4326.0
AMH -4383.0
WNT9A -4397.0
IFT140 -4423.0
FMNL2 -4424.0
HTR6 -4426.0
WNT4 -4485.0
CHD4 -4515.0
TNRC6B -4518.0
ARHGEF35 -4533.0
PDHA1 -4581.0
ARHGEF7 -4583.0
CPT1B -4584.0
MCHR1 -4598.0
SPRY2 -4603.0
CBX2 -4617.0
PTPRA -4626.0
GPC1 -4627.0
DOCK3 -4640.0
RHPN2 -4650.0
SMAD5 -4651.0
RDH10 -4665.0
ATP2A1 -4667.0
RCE1 -4674.0
WNT3 -4684.0
SPPL2B -4688.0
BCL2 -4704.0
PTCH2 -4708.0
OR14J1 -4716.0
GPC4 -4730.0
ZWINT -4742.0
ADAM12 -4744.0
TAS2R3 -4767.0
CNKSR2 -4781.0
OPRD1 -4782.0
PNOC -4890.0
GUCA1B -4897.0
WNT16 -4921.0
BTRC -4924.0
HRH1 -4934.0
MAD1L1 -4981.0
CDK2 -5006.0
RGS5 -5029.0
SMAD9 -5040.0
CIT -5064.0
CRHR2 -5119.0
SPTBN2 -5129.0
CENPO -5135.0
RCC2 -5148.0
RARG -5153.0
GNG7 -5198.0
CCNT2 -5205.0
NOTCH4 -5229.0
KHDRBS2 -5270.0
PTENP1 -5280.0
PSMA3 -5285.0
REEP2 -5289.0
RGS1 -5296.0
RHPN1 -5327.0
TIA1 -5344.0
FGFR1 -5352.0
JUP -5353.0
CENPM -5376.0
IKBKB -5386.0
EFCAB7 -5419.0
NEFL -5425.0
S100B -5457.0
NOXA1 -5464.0
ARHGAP33 -5517.0
GPR161 -5538.0
RHOT2 -5546.0
RHOBTB2 -5551.0
ARHGEF1 -5559.0
MAMLD1 -5584.0
TNRC6A -5613.0
MST1R -5615.0
DNAJB1 -5672.0
SRGAP3 -5675.0
DGKZ -5681.0
SOS1 -5700.0
SCUBE2 -5701.0
RASGEF1A -5704.0
DLG2 -5717.0
FNTA -5724.0
PSMB10 -5735.0
GPSM1 -5766.0
STAP2 -5775.0
PGF -5814.0
SCMH1 -5839.0
TRIB3 -5843.0
NCBP1 -5853.0
HRH4 -5875.0
HNRNPA1 -5924.0
TAS2R5 -5926.0
INCENP -5956.0
MUC20 -5962.0
TLR9 -5999.0
MFNG -6008.0
EVC2 -6012.0
OR5A2 -6014.0
SORCS3 -6044.0
PSMA5 -6053.0
SEH1L -6069.0
PSME4 -6087.0
SALL4 -6112.0
WWTR1 -6131.0
VIPR1 -6156.0
RPS6 -6160.0
UTS2B -6163.0
MRAS -6172.0
TCF7L2 -6185.0
CKAP5 -6246.0
LPAR3 -6276.0
DUSP4 -6287.0
ARHGEF10L -6295.0
STAG1 -6347.0
CENPQ -6366.0
FOXO6 -6367.0
TJP1 -6374.0
PPARD -6394.0
CHRM5 -6404.0
ZDHHC21 -6453.0
CTBP1 -6456.0
RRH -6491.0
FZD7 -6508.0
FZD6 -6525.0
NF2 -6540.0
H2BU1 -6555.0
FBXW7 -6600.0
FGF23 -6622.0
GPR15 -6636.0
OR2A7 -6650.0
DUSP16 -6655.0
CENPU -6692.0
OR2A1 -6705.0
SGO1 -6715.0
TRRAP -6722.0
OBSCN -6727.0
USP13 -6737.0
NR4A1 -6756.0
CASR -6767.0
GRK7 -6773.0
OR5AS1 -6779.0
ARHGEF18 -6799.0
PEA15 -6825.0
SPRED3 -6835.0
CD80 -6841.0
PDE8B -6846.0
HSP90AB1 -6863.0
KPNA2 -6910.0
GREB1 -6937.0
RPS27A -6938.0
TLE1 -6942.0
ARHGEF5 -6944.0
PDE8A -6957.0
CCND1 -6970.0
USP21 -6972.0
INPP5B -7024.0
CXXC5 -7037.0
DRAP1 -7046.0
BCR -7071.0
CNKSR1 -7089.0
GNAL -7090.0
ALDH8A1 -7123.0
ACKR4 -7128.0
TAS2R4 -7129.0
GPBAR1 -7132.0
FZD8 -7138.0
DISP2 -7144.0
IL2RA -7161.0
NAPEPLD -7168.0
FZD3 -7186.0
FLT4 -7216.0
ACVR1C -7219.0
PTPRK -7262.0
RBFOX2 -7280.0
TNF -7308.0
MTA2 -7317.0
YWHAQ -7340.0
RTP5 -7388.0
NET1 -7419.0
PDE4B -7429.0
TLE2 -7449.0
PPP5C -7462.0
WDR19 -7511.0
TRAT1 -7535.0
ARHGAP12 -7547.0
PSMA8 -7606.0
ARHGAP42 -7608.0
ITGB3BP -7621.0
ITPR1 -7629.0
CCR8 -7641.0
CCR7 -7649.0
EDN3 -7653.0
CNR2 -7662.0
ADRB1 -7674.0
CYSLTR1 -7675.0
DYNC1H1 -7685.0
GHSR -7695.0
IKZF1 -7704.0
PSEN2 -7718.0
NUP133 -7762.0
SPTBN1 -7764.0
HSPG2 -7779.0
PIP4K2B -7788.0
ARHGAP11B -7789.0
GNG2 -7795.0
CHN1 -7833.0
ZFYVE9 -7848.0
RET -7856.0
UCHL5 -7861.0
CCR6 -7862.0
SCAI -7879.0
ARHGAP17 -7888.0
KNTC1 -7897.0
GLI3 -7910.0
VEGFB -7929.0
HNRNPH1 -7932.0
MAD2L1 -7944.0
DYNC2H1 -7947.0
ABCG1 -7961.0
WNT7A -7966.0
DGKA -7980.0
PRKCE -8001.0
RAMP1 -8039.0
PDK2 -8047.0
LEF1 -8076.0
CXXC4 -8078.0
OR2I1P -8104.0
DGKQ -8149.0
PHC3 -8152.0
AXIN2 -8154.0
CXCL10 -8160.0
ARHGAP39 -8166.0
PRKAB2 -8172.0
CDON -8176.0
NTRK1 -8193.0
CDKN1B -8207.0
ADCY5 -8235.0
HES1 -8266.0
METAP1 -8295.0
CENPK -8334.0
BMPR1A -8335.0
DLG1 -8336.0
HDAC6 -8337.0
SMAD4 -8351.0
MAPKAPK5 -8364.0
LFNG -8372.0
KLC4 -8376.0
THBS4 -8396.0
PHC1 -8402.0
CTNND1 -8403.0
ARHGAP25 -8441.0
PRKG2 -8477.0
GNRH1 -8483.0
RASGRP2 -8529.0
MEN1 -8538.0
E2F5 -8568.0
MCF2L -8571.0
PDGFB -8577.0
DAGLA -8578.0
GNRHR2 -8582.0
RDH16 -8604.0
FGF22 -8607.0
RUVBL1 -8612.0
CENPH -8633.0
RLN2 -8636.0
SPRED1 -8639.0
TPH1 -8640.0
STMN1 -8663.0
SH2B1 -8670.0
TGIF1 -8682.0
GFRA2 -8689.0
ESRP2 -8691.0
PML -8693.0
NRP1 -8717.0
TNKS -8738.0
BCO2 -8744.0
PLEKHG5 -8758.0
FGF9 -8761.0
ARHGEF19 -8776.0
SRC -8820.0
TRIM33 -8823.0
GPR55 -8827.0
ARHGAP10 -8847.0
CCR5 -8861.0
KIF5A -8869.0
CILP -8873.0
ARHGAP5 -8885.0
ADORA1 -8946.0
GUCY2D -8954.0
CYSLTR2 -8970.0
SKA2 -8999.0
WNT1 -9014.0
KLC2 -9059.0
POGLUT1 -9094.0
ESR1 -9122.0
PTGIR -9126.0
PSMC4 -9127.0
SYNGAP1 -9140.0
NFATC1 -9147.0
NDC80 -9165.0
TBP -9167.0
S1PR1 -9211.0
PRMT1 -9229.0
EDN1 -9248.0
ESR2 -9250.0
XCL1 -9270.0
FGFBP3 -9275.0
CYP4V2 -9298.0
HHAT -9301.0
TRPC3 -9343.0
RYK -9346.0
EED -9348.0
CYLD -9359.0
DUSP2 -9373.0
GAS1 -9378.0
RASGRP3 -9414.0
MAPK8 -9428.0
KDM1A -9430.0
MTA3 -9433.0
ICOS -9434.0
GHRL -9461.0
FOXO1 -9465.0
CCNT1 -9469.0
PIK3R1 -9505.0
ATP6V1G2 -9515.0
NUP43 -9517.0
NCBP2 -9558.0
MYO9A -9588.0
CENPT -9606.0
ID3 -9614.0
RGS9 -9636.0
OR52N4 -9656.0
RICTOR -9670.0
OR4D1 -9690.0
CXCR5 -9727.0
CHD3 -9737.0
EZH2 -9741.0
F2R -9750.0
HEY2 -9752.0
RPS27 -9756.0
MTOR -9767.0
COL9A2 -9770.0
ACKR3 -9771.0
NOG -9796.0
RAPGEF1 -9826.0
BMI1 -9829.0
GOPC -9831.0
DDX5 -9843.0
WNT10A -9848.0
A2M -9870.0
FLT3LG -9894.0
CCR4 -9900.0
LAMA2 -9911.0
WNT10B -9917.0
GNAO1 -9936.0
GPR150 -9942.0
CLIP3 -9943.0
CAMK4 -9956.0
RBL1 -9959.0
PSME1 -9991.0
SSTR3 -10021.0
PORCN -10074.0
CBY1 -10077.0
TGIF2 -10105.0
WWP1 -10106.0
CDC14A -10119.0
PRDM4 -10148.0
TCF7 -10173.0
RASGRF2 -10175.0
EBAG9 -10187.0
RNF31 -10192.0
REEP6 -10201.0
CD28 -10202.0
COL6A2 -10206.0
GPAM -10241.0
AXIN1 -10285.0
CSNK1E -10298.0
RPGRIP1L -10301.0
ITPR3 -10308.0
DGKK -10314.0
GRAP -10321.0
PSME2 -10336.0
SMURF2 -10340.0
MIR25 -10350.0
CYFIP2 -10367.0
LRIG1 -10389.0
RDH14 -10397.0
NAB2 -10400.0
ABHD12 -10401.0
NUP107 -10421.0
PRKX -10428.0
WDR35 -10457.0
RPTOR -10464.0
FAM13B -10519.0
NUP160 -10557.0
ACVR2B -10569.0
CXCL9 -10574.0
RDH13 -10602.0
CX3CR1 -10624.0
RHOH -10626.0
MKS1 -10634.0
ABHD17A -10672.0
GPR25 -10677.0
IFT172 -10736.0
KDM4C -10749.0
ITGA3 -10750.0
OTUD3 -10763.0
KAT2A -10771.0
DSN1 -10773.0
DRD4 -10808.0
ARHGEF39 -10833.0
XCL2 -10854.0
PTPN7 -10868.0
PDE7A -10882.0
TP53 -10893.0
MIS12 -10903.0
P2RY11 -10907.0
ABI2 -10915.0
PELP1 -10928.0
TNFAIP3 -10950.0
JAK1 -10955.0
P2RY6 -10964.0
ID2 -10969.0
TIAM2 -10979.0
CCL5 -10985.0
KIT -11004.0
JAG2 -11044.0
SLC24A1 -11057.0
THEM4 -11069.0
MIB2 -11073.0
RIPK1 -11074.0
WWOX -11085.0
CCL28 -11088.0
EEF2K -11089.0
CCR3 -11109.0
LPAR5 -11110.0
SKI -11113.0
PLCG1 -11120.0
BIRC3 -11125.0
DVL2 -11152.0
RGS12 -11170.0
TTC21B -11179.0
CXCR6 -11180.0
MC1R -11184.0
RASA4 -11206.0
IL5RA -11211.0
CNOT6L -11248.0
CDK4 -11256.0
PPP2R5C -11265.0
PEBP1 -11270.0
GRM2 -11275.0
SOX13 -11280.0
MXD4 -11285.0
OFD1 -11296.0
AMER1 -11301.0
PDE3B -11322.0
PSMB9 -11324.0
PYGO2 -11326.0
CUL1 -11330.0
CASP8 -11336.0
ACVR2A -11338.0
RHOC -11360.0
PIP4K2C -11371.0
PDE6B -11387.0
DGKE -11390.0
SPTAN1 -11426.0
RAG1 -11432.0
NCK1 -11454.0
RTP4 -11457.0
CDH1 -11500.0
S1PR2 -11503.0
KIF7 -11533.0
SPDL1 -11534.0
PDGFRB -11545.0
ATP6V0E2 -11555.0
CMKLR1 -11560.0
RPS6KA5 -11594.0
CXCR3 -11603.0
PRKCZ -11629.0
NEURL1 -11633.0
DUSP8 -11639.0
FZD4 -11650.0
FYN -11675.0
LAT -11694.0
GPR20 -11696.0
PTGER4 -11697.0
NCAM1 -11706.0
CCNE1 -11707.0
BUB3 -11709.0
RANGAP1 -11722.0
ZWILCH -11724.0
STAT1 -11727.0
SMAD3 -11745.0
TRAF2 -11746.0
PARP1 -11764.0
ALDH1A1 -11765.0
AGRN -11770.0
FGFRL1 -11778.0
CENPL -11782.0
FGFR2 -11785.0
GPR183 -11803.0
CENPP -11814.0
CAMK2D -11816.0
RASA3 -11820.0
TNRC6C -11828.0
TULP3 -11833.0
LCK -11838.0
AKT3 -11849.0
SMAD7 -11872.0
DLL1 -11885.0
SCT -11886.0
GPR18 -11887.0
CENPC -11888.0
ADRB2 -11892.0
MADD -11899.0
DLG3 -11922.0
P2RY10 -11926.0
PTCH1 -11936.0
P2RY14 -11940.0
TRAF1 -11947.0
PHLPP2 -11948.0
TLE5 -11957.0
PRKACB -11959.0
KIF3A -11972.0
RASGRP1 -11974.0
CCL4 -11976.0
BCL9L -11981.0
ARAP2 -11984.0
PRR5 -11985.0
MOV10 -11991.0
RASAL3 -12014.0
PIK3R3 -12015.0
PTGDR -12021.0
ARHGEF3 -12022.0
NMT2 -12035.0
CCDC88C -12041.0
IL2RG -12050.0
IL3RA -12057.0
DHRS3 -12084.0
GNGT2 -12086.0
FMNL3 -12087.0
OTUD7B -12095.0
GIPR -12100.0
KDM3A -12102.0
AKR1C3 -12104.0
FPR3 -12116.0
RNF43 -12121.0
PPP3CC -12126.0
PRKCQ -12127.0
PTGDR2 -12132.0
RALGDS -12140.0
YES1 -12142.0
VIPR2 -12153.0
GPR68 -12154.0
RBBP7 -12155.0
GATA3 -12191.0
EVL -12207.0
ATP6V0A2 -12211.0
ARHGEF25 -12219.0
AMOT -12223.0
NMUR1 -12226.0
DUSP5 -12227.0
SMPD3 -12234.0
FGFBP2 -12244.0
PDGFD -12247.0
RTKN -12249.0
MATK -12255.0
C3 -12262.0
ARHGAP8 -12284.0
TAGAP -12285.0
LGR6 -12286.0
PTPRS -12291.0
MAGED1 -12295.0
ARL4C -12296.0
ARHGEF9 -12299.0
S1PR5 -12315.0
ERBB2 -12320.0
PRKCH -12324.0
AXL -12331.0
CCL2 -12341.0
RHOF -12344.0
IL2RB -12347.0
RUNX3 -12352.0
SH2D2A -12359.0
GZMB -12361.0
TFDP2 -12364.0
FASLG -12371.0


Hemostasis

Hemostasis
496
set Hemostasis
setSize 550
pANOVA 5.25e-23
s.dist 0.246
p.adjustANOVA 1.02e-20



Top enriched genes

Top 20 genes
GeneID Gene Rank
SIRPA 9510
F12 9492
F5 9485
CYB5R1 9460
GNA15 9452
CD36 9444
SERPINB2 9438
NFE2 9431
PRKACA 9429
MAFG 9407
ITGAM 9398
CLU 9371
GNG10 9349
APLP2 9347
GRB2 9304
QSOX1 9298
CD63 9287
HBE1 9275
ALDOA 9249
LHFPL2 9224

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SIRPA 9510.0
F12 9492.0
F5 9485.0
CYB5R1 9460.0
GNA15 9452.0
CD36 9444.0
SERPINB2 9438.0
NFE2 9431.0
PRKACA 9429.0
MAFG 9407.0
ITGAM 9398.0
CLU 9371.0
GNG10 9349.0
APLP2 9347.0
GRB2 9304.0
QSOX1 9298.0
CD63 9287.0
HBE1 9275.0
ALDOA 9249.0
LHFPL2 9224.0
FERMT3 9223.0
PHF21A 9216.0
SERPINB8 9205.0
PLA2G4A 9180.0
APP 9177.0
BSG 9172.0
SERPINA1 9168.0
MAPK14 9104.0
HBD 9100.0
ACTN1 9094.0
THBD 9082.0
SYK 9076.0
RCOR1 9073.0
TNFRSF10D 9072.0
HBB 9054.0
PIK3CB 9038.0
STXBP2 9035.0
PRKCD 9008.0
GNAQ 8993.0
MAPK3 8953.0
ITGB2 8942.0
CLEC1B 8931.0
SELL 8912.0
CRK 8906.0
ITGA2B 8893.0
F13A1 8876.0
HGF 8863.0
TOR4A 8861.0
MRVI1 8854.0
VTI1B 8850.0
GNG5 8815.0
RAC1 8793.0
LAMP2 8786.0
SLC16A3 8783.0
SRGN 8761.0
APBB1IP 8744.0
ITGA1 8729.0
HBG2 8722.0
TIMP1 8677.0
H3-3A 8661.0
CDK5 8616.0
PRKAR1A 8607.0
CAPZA2 8597.0
ANXA2 8544.0
TLN1 8525.0
ARRB2 8490.0
RHOG 8487.0
CLEC3B 8480.0
FGR 8478.0
SELP 8457.0
SLC8A1 8444.0
P2RX1 8436.0
CEACAM1 8429.0
PLAUR 8424.0
GATA1 8410.0
CD44 8333.0
CD99 8326.0
TNFRSF10B 8321.0
RHOA 8319.0
KIF3C 8306.0
GNB1 8294.0
ITGB3 8291.0
FN1 8284.0
MERTK 8257.0
SYTL4 8256.0
KIF5B 8239.0
PPP2CA 8234.0
PRCP 8218.0
ANXA5 8210.0
CFL1 8186.0
KIF1B 8184.0
EGF 8179.0
HBG1 8157.0
GNB2 8141.0
CAPZA1 8135.0
FCER1G 8131.0
CAP1 8111.0
GYPB 8109.0
JAML 8107.0
GNAI2 8075.0
GAS6 8063.0
F11R 8058.0
ATP2A2 8038.0
LY6G6F 8023.0
CAPZB 8015.0
ORM1 7971.0
DGKG 7958.0
GNAI3 7953.0
PRKAR1B 7918.0
GNAS 7909.0
VAV1 7896.0
CALU 7894.0
RAF1 7879.0
PECAM1 7855.0
P2RY1 7852.0
GYPA 7820.0
LYN 7809.0
KIF1C 7799.0
CD99L2 7793.0
SCCPDH 7787.0
PROS1 7758.0
DOCK2 7725.0
MMRN1 7714.0
PPP2CB 7712.0
MGLL 7694.0
DOCK4 7692.0
ITGA5 7659.0
P2RX4 7630.0
SH2B2 7609.0
CDC42 7537.0
ESAM 7531.0
DOCK5 7524.0
GP9 7506.0
MAPK1 7493.0
SERPINE1 7483.0
GP1BB 7470.0
VEGFA 7467.0
ABCC4 7434.0
STXBP3 7424.0
KLC3 7377.0
TAGLN2 7367.0
AKAP10 7344.0
SPARC 7339.0
ITGAX 7337.0
GNB4 7336.0
VCL 7328.0
DOCK1 7314.0
RAP1A 7305.0
PIK3R6 7270.0
PSAP 7145.0
SLC7A7 7123.0
RAB5A 7103.0
PRKCB 7097.0
HSPA5 7029.0
GYPC 7027.0
F8 7022.0
TREM1 7009.0
WDR1 6976.0
VEGFC 6906.0
PRKG1 6901.0
MMP1 6891.0
S100A10 6860.0
ITPK1 6851.0
CEACAM3 6838.0
KCNMB4 6825.0
GP6 6818.0
KCNMA1 6787.0
PPP2R5B 6774.0
PRTN3 6762.0
MFN2 6750.0
PRKAR2B 6741.0
H3C15 6699.5
PDE5A 6678.0
CD58 6647.0
VWF 6641.0
SDC4 6637.0
SRI 6554.0
GNG11 6495.0
TUBA4A 6484.0
TSPAN7 6469.0
SERPINE2 6451.0
IRF2 6427.0
ATP1B2 6378.0
GTPBP2 6331.0
TMSB4X 6295.0
JAM3 6294.0
GP1BA 6279.0
EHD2 6167.0
PRKAR2A 6166.0
PDPK1 6136.0
ITGAV 6106.0
PTPN6 6096.0
MICAL1 6071.0
PPBP 6042.0
DOCK8 6028.0
ORAI2 6010.0
KIF13B 5998.0
THBS1 5951.0
CD9 5940.0
PPP2R5A 5897.0
PDE1B 5874.0
SERPINB6 5854.0
ITPR2 5842.0
GNA13 5836.0
DAGLB 5820.0
PTPN1 5722.0
PF4 5707.0
YWHAZ 5624.0
A1BG 5559.0
KLC1 5523.0
KIF23 5510.0
HDAC2 5482.0
PFN1 5459.0
PHACTR2 5410.0
SDC2 5397.0
NRAS 5363.0
RAD51B 5318.0
PTPN11 5314.0
PDGFA 5293.0
SLC3A2 5222.0
CSK 5219.0
ECM1 5176.0
RAC2 5163.0
TGFB1 5153.0
TBXA2R 5148.0
KIF20A 5096.0
ACTN4 5049.0
PIK3R2 5010.0
PLCG2 5006.0
CEACAM8 4956.0
OLA1 4914.0
EHD3 4904.0
PLAU 4903.0
VAV3 4894.0
HMG20B 4839.0
P2RY12 4821.0
F2RL3 4773.0
PIK3CA 4629.0
PPP2R1A 4589.0
LRP8 4568.0
CEACAM6 4509.0
PTK2 4462.0
SLC16A1 4455.0
EHD1 4358.0
CD109 4316.0
SELPLG 4301.0
GNG8 4296.0
KIF9 4253.0
ITGA2 4168.0
SHC1 4161.0
STIM1 3938.0
SH2B3 3910.0
DOCK11 3876.0
KIF3B 3740.0
KRAS 3702.0
ALB 3668.0
AKT1 3614.0
PICK1 3594.0
KIF4A 3585.0
P2RX7 3475.0
CD84 3425.0
RAB27B 3386.0
GNA12 3367.0
ENDOD1 3361.0
KCNMB3 3343.0
PDE11A 3331.0
GNAI1 3329.0
TIMP3 3296.0
GNA11 3259.0
RAP1B 3206.0
JMJD1C 3192.0
SLC7A5 3012.0
RACGAP1 2848.0
CHID1 2811.0
KIF16B 2785.0
JAK2 2691.0
MPL 2634.0
SDC3 2599.0
ANGPT1 2562.0
MANF 2550.0
KIF27 2549.0
DOCK6 2531.0
VPS45 2496.0
OLR1 2486.0
CD177 2457.0
PPP2R5D 2421.0
ADRA2A 2271.0
PLEK 1999.0
ARRB1 1998.0
CFD 1984.0
CAV1 1969.0
SLC7A8 1916.0
SLC8A3 1886.0
PIK3CG 1833.0
TNFRSF10A 1815.0
GRB14 1730.0
APOOL 1609.0
SLC16A8 1608.0
CD48 1493.0
NOS1 1365.0
GP5 1295.0
RHOB 1254.0
PF4V1 1211.0
TTN 1195.0
KIF6 1147.0
PRKCA 1132.0
TF 1102.0
MAFK 901.0
GNG3 890.0
KIF11 787.0
KIF2C 726.0
SLC7A9 622.0
STX4 606.0
HDAC1 587.0
GNB5 512.0
FLNA 483.0
MAFF 426.0
IGHV1-2 360.0
CENPE 332.0
MYB 302.0
JAM2 243.0
IGHV2-5 230.0
ABL1 226.0
AK3 164.0
IGHV3-53 103.0
ITGB1 -94.0
KIF18B -143.0
PPP2R1B -241.0
KIFC1 -249.0
GLG1 -319.0
ITGA10 -322.0
P2RX5 -435.0
IGHV3-7 -441.0
KCNMB1 -464.0
DGKD -501.0
IGHV1-46 -618.0
IGHV3-48 -668.0
PPP2R5E -680.0
TMX3 -775.0
IGKV3-11 -781.0
PDE2A -808.0
C1QBP -822.0
ATP2A3 -914.0
DOK2 -952.0
IGKV1-39 -989.0
IGLV7-46 -1016.0
KIF2A -1069.0
VPREB3 -1146.0
LCP2 -1156.0
IGKV1-5 -1184.0
PLAT -1242.0
IGHA2 -1274.0
IGLV2-8 -1294.0
IGKV5-2 -1298.0
IGHV3-23 -1317.0
ATP1B3 -1347.0
IGHV3-13 -1443.0
IGLV2-18 -1524.0
IGKV1-16 -1528.0
IGLV4-69 -1559.0
IGKV1D-39 -1574.0
KIFC2 -1642.0
IGHV1-69 -1822.0
IGLV10-54 -1884.0
TRPC6 -1935.0
PLG -1977.0
PCYOX1L -2009.0
IGLV1-36 -2030.0
IGKV2-30 -2045.0
NOS3 -2059.0
CALM1 -2081.0
IGLV7-43 -2089.0
IGLV3-19 -2111.0
IGHV3-11 -2134.0
GNG4 -2154.0
IGHM -2190.0
F2RL2 -2284.0
IGHA1 -2291.0
IGKV3-15 -2297.0
PIK3R5 -2304.0
DOCK7 -2369.0
GNB3 -2397.0
IGKV1-33 -2424.0
IGHV3-30 -2484.0
IGKV4-1 -2532.0
ORM2 -2564.0
MAGED2 -2687.0
SERPIND1 -2722.0
KIF18A -2742.0
TFPI -2818.0
ABHD6 -2829.0
IGKV1-17 -2871.0
IGLV2-23 -2878.0
IGLV6-57 -2885.0
IGHV4-59 -2892.0
IGLV2-11 -2905.0
RAPGEF3 -2911.0
IGHV3-33 -2988.0
IGHV4-34 -3016.0
ITIH3 -3017.0
IGKV3-20 -3085.0
IGHV2-70 -3138.0
DGKH -3178.0
KIF15 -3249.0
IGLV1-44 -3258.0
HRAS -3382.0
AAMP -3636.0
MIF -3863.0
IGKV3D-20 -3894.0
ANGPT2 -3990.0
INPP5D -4038.0
VAV2 -4055.0
IGLV3-1 -4159.0
JCHAIN -4240.0
ANGPT4 -4384.0
IGKC -4428.0
RBSN -4542.0
IGHV4-39 -4582.0
GPC1 -4627.0
DOCK3 -4640.0
ATP2A1 -4667.0
IGLV3-21 -4735.0
IGLV1-40 -4788.0
SOD1 -4862.0
KIF26A -4925.0
IGLV3-25 -4933.0
IGLV1-51 -4956.0
MFN1 -4966.0
CDK2 -5006.0
ATP2B4 -5030.0
GUCY1B2 -5054.0
ITGA6 -5094.0
GNG7 -5198.0
IGLC7 -5281.0
IGLV8-61 -5427.0
IGKV1-12 -5446.0
IGLC3 -5477.0
CARMIL1 -5482.0
IGLC2 -5510.0
P2RX6 -5541.0
IGKV2D-28 -5634.0
DGKZ -5681.0
SOS1 -5700.0
SLC7A11 -5719.0
IGKV2-28 -5808.0
IGLV5-45 -5869.0
IGLV3-27 -5874.0
IGLV1-47 -6018.0
IGLC1 -6157.0
ITIH4 -6208.0
L1CAM -6358.0
SERPINF2 -6574.0
BRPF3 -6615.0
SLC7A6 -6690.0
KIF21B -6702.0
PPIA -6766.0
KIF28P -6770.0
ORAI1 -7096.0
IGLV3-12 -7358.0
TGFB2 -7492.0
PDE9A -7584.0
ITPR1 -7629.0
SELENOP -7771.0
GNG2 -7795.0
RAD51C -7807.0
KIF20B -7822.0
NHLRC2 -7835.0
TGFB3 -7891.0
VEGFB -7929.0
DGKA -7980.0
PRKCE -8001.0
CABLES2 -8110.0
DGKQ -8149.0
ATP2B1 -8286.0
IGLV2-14 -8345.0
TEX264 -8366.0
KLC4 -8376.0
CDC37L1 -8470.0
PRKG2 -8477.0
IRF1 -8510.0
RASGRP2 -8529.0
PDGFB -8577.0
DAGLA -8578.0
KIFAP3 -8619.0
SH2B1 -8670.0
SRC -8820.0
KIF5C -8865.0
KIF5A -8869.0
KLKB1 -9019.0
KLC2 -9059.0
ATP1B1 -9118.0
PTGIR -9126.0
WEE1 -9145.0
CD244 -9216.0
CBX5 -9272.0
CABLES1 -9302.0
TRPC3 -9343.0
ZFPM2 -9423.0
KDM1A -9430.0
PIK3R1 -9505.0
F2R -9750.0
PPIL2 -9793.0
GATA2 -9800.0
A2M -9870.0
SIRPG -9884.0
FAM3C -10062.0
PROC -10098.0
ZFPM1 -10195.0
ITPR3 -10308.0
DGKK -10314.0
ABHD12 -10401.0
SIN3A -10493.0
DOCK9 -10708.0
DOCK10 -10728.0
ITGA3 -10750.0
PROCR -10802.0
ITGAL -10847.0
TP53 -10893.0
HABP4 -10921.0
ITGA4 -11043.0
CTSW -11117.0
PLCG1 -11120.0
SERPING1 -11197.0
PPP2R5C -11265.0
DGKE -11390.0
CD74 -11419.0
AKAP1 -11442.0
LGALS3BP -11459.0
PRKCZ -11629.0
KIF26B -11663.0
FYN -11675.0
LAT -11694.0
KIF19 -11733.0
CD2 -11805.0
KIF21A -11837.0
LCK -11838.0
GATA6 -11928.0
PRKACB -11959.0
KIF3A -11972.0
RASGRP1 -11974.0
PIK3R3 -12015.0
GNGT2 -12086.0
CD47 -12114.0
PRKCQ -12127.0
YES1 -12142.0
GATA3 -12191.0
PAFAH2 -12322.0
PRKCH -12324.0
KIF22 -12358.0
SPN -12375.0


Metabolism

Metabolism
634
set Metabolism
setSize 1772
pANOVA 1.78e-22
s.dist 0.139
p.adjustANOVA 3.04e-20



Top enriched genes

Top 20 genes
GeneID Gene Rank
PPARG 9522
PLBD1 9521
CTSA 9514
IDH1 9507
VCAN 9505
CYP1B1 9502
NMNAT2 9500
CYP19A1 9497
IMPA2 9493
PLB1 9490
MGST1 9482
PGD 9481
BST1 9480
DSE 9479
FAH 9459
TALDO1 9456
KCNG2 9455
GNA15 9452
HADHB 9450
CD36 9444

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PPARG 9522
PLBD1 9521
CTSA 9514
IDH1 9507
VCAN 9505
CYP1B1 9502
NMNAT2 9500
CYP19A1 9497
IMPA2 9493
PLB1 9490
MGST1 9482
PGD 9481
BST1 9480
DSE 9479
FAH 9459
TALDO1 9456
KCNG2 9455
GNA15 9452
HADHB 9450
CD36 9444
HSD3B7 9441
PLIN3 9437
PGAM1 9435
ACSS2 9430
PRKACA 9429
GGT1 9426
PYGL 9417
SLC25A37 9415
SULT1B1 9409
PKM 9391
ADIPOR1 9390
HK3 9385
CA1 9380
BLVRB 9379
PCTP 9376
ACOX2 9373
GAPDH 9368
GNS 9360
PLCD3 9352
TSPO 9351
GNG10 9349
MAOA 9346
PGM2 9344
TKT 9342
OPLAH 9330
TNFAIP8L3 9316
GPX1 9314
CDA 9310
PLD1 9306
IMPDH1 9294
ALDH4A1 9281
PFKFB4 9271
HK2 9266
PC 9263
LTA4H 9261
CHP1 9258
AGPAT2 9256
TPST1 9251
ALDOA 9249
GSR 9235
TK2 9234
NMNAT1 9228
OAZ1 9221
ACSL1 9217
SGMS2 9213
ALAS2 9196
CES1 9192
OLAH 9184
PLA2G4A 9180
BSG 9172
DPYD 9166
ACER3 9165
DGAT2 9158
VNN2 9153
PTGR1 9126
CRLS1 9116
FIG4 9115
CERS2 9108
VNN1 9092
HYAL2 9088
GSTO1 9084
LRP1 9080
SBF2 9078
HK1 9071
MTMR3 9069
ARF1 9064
AK4 9062
GM2A 9059
PIK3CB 9038
SLC6A8 9036
VAPA 9033
NEU1 9029
INPPL1 9028
SLC2A3 9021
CARM1 9020
GYG1 9013
BCKDK 9010
GLUL 9006
G6PD 9004
PAPSS1 9003
ALOX5 9001
LYVE1 8999
GNAQ 8993
SUMF1 8991
ADCY3 8984
GK 8973
GBA 8969
PPT1 8950
PNPLA2 8939
BPGM 8935
MTF1 8925
NUDT16 8923
CRAT 8920
PLCB3 8916
PISD 8908
CHST15 8905
CYB5R3 8903
ME1 8892
ENO1 8890
TBXAS1 8862
ACOX1 8859
HSD17B4 8858
CHPT1 8846
GALK1 8842
B4GALT5 8830
SLC19A1 8822
NUP58 8820
ITPKC 8818
GNG5 8815
OAT 8814
OAZ2 8810
PHKB 8809
FAR2 8808
ACSL4 8802
SLC16A3 8783
SGMS1 8782
HEXB 8776
ARG1 8759
FAR1 8754
PLA2G15 8747
PECR 8739
GLCE 8735
SERINC2 8733
AMPD3 8732
GLB1 8725
TCN2 8721
SORD 8716
GCKR 8713
ELOVL3 8710
MGST2 8706
ETHE1 8705
HADHA 8694
PGK1 8672
ST3GAL2 8669
SMARCD3 8668
BMX 8664
ALDH3B1 8663
ETFA 8658
PFKFB3 8656
PGS1 8654
GDE1 8642
LDHA 8637
PDXK 8635
MAOB 8626
NT5C2 8617
LPCAT3 8609
PRKAR1A 8607
LPCAT2 8606
PUDP 8603
UPP1 8593
SPTLC1 8588
GLRX5 8581
NQO2 8575
LPGAT1 8574
GLA 8570
CACNA1E 8552
SPTLC2 8547
ACSS3 8546
GNPDA1 8541
MBOAT7 8536
ASAH1 8529
GPCPD1 8527
SLC44A1 8526
PHKA2 8524
ALAD 8514
GMPR 8509
DERA 8500
MLX 8497
PSMB7 8485
GLTP 8477
HPSE 8476
PTGS1 8467
PTEN 8460
MTHFS 8455
POR 8454
SLCO2B1 8450
GALC 8443
NDUFB3 8430
FUT7 8428
ALOX15B 8427
PNP 8419
PSMD4 8402
SDHC 8390
MBOAT2 8362
ENTPD1 8360
VDR 8348
CD44 8333
HNMT 8317
SLC27A1 8305
GNB1 8294
ACAA1 8292
ACADVL 8290
TXN 8285
HMOX1 8278
COMT 8273
MTHFD2 8267
PLIN2 8261
PSME3 8251
NDUFB9 8237
PPP2CA 8234
CSGALNACT2 8228
SP1 8193
TXNRD1 8192
HAAO 8183
GPAT3 8177
NDUFAF1 8167
AGPAT1 8158
NDST1 8156
IQGAP1 8152
LYPLA1 8143
GNB2 8141
GBE1 8137
CHSY1 8116
SEC24D 8115
LBR 8102
PSMB5 8101
ALDH2 8095
HMGCR 8094
COX15 8082
GNAI2 8075
UQCRH 8073
ETFDH 8052
ARNT 8047
MTMR14 8032
ACOT8 8018
IPMK 8014
HSD17B11 8008
ENTPD7 8002
NCOR2 7985
BCAT1 7970
SLC9A1 7969
GAA 7968
MTMR10 7964
PLPP3 7955
SRD5A1 7951
PFKFB2 7946
RAB4A 7941
DDAH2 7939
GLRX 7932
NUP214 7921
PRKAR1B 7918
ABHD5 7915
GNAS 7909
NDST2 7892
CERT1 7889
TBL1X 7887
ALOX5AP 7881
MTMR6 7878
SLC35D2 7872
UQCRC1 7859
PCYT1B 7858
MPST 7854
PSMD6 7846
ACSL3 7840
ALAS1 7804
CHPF2 7803
NADK 7774
HAL 7762
TST 7744
GLIPR1 7739
ARF3 7732
GUSB 7723
COX7A2L 7719
PPP2CB 7712
TMLHE 7710
PNPLA8 7709
ELOVL7 7706
FADS1 7699
MGLL 7694
ETFB 7688
COASY 7672
GMPR2 7668
SLC25A44 7662
SEC24A 7660
SPHK1 7657
SLC36A4 7655
NFYC 7653
SEPHS2 7651
RGL1 7647
ATP5PD 7637
DHRS7B 7629
SULT1A1 7624
PSMD9 7620
PDSS1 7619
CDK19 7618
SAMD8 7614
HPD 7593
SDHB 7587
PANK2 7583
NDUFB1 7578
ARSB 7572
CRYM 7565
ALOX12 7559
SUCLA2 7558
GPD2 7555
ATP5PB 7551
MED8 7535
NAMPT 7525
MLXIPL 7517
RXRA 7495
AHR 7479
NUDT4 7423
CKM 7420
HPGD 7416
NR1H2 7415
NAPRT 7412
PSMD2 7411
MANBA 7386
STARD3NL 7374
FDFT1 7372
ARSD 7365
PLD3 7364
ABCD1 7346
GNB4 7336
SEC23A 7335
FBP1 7330
PSMA1 7329
FUT4 7307
RAP1A 7305
DLD 7303
UGP2 7284
SLC25A11 7278
G0S2 7272
PIK3R6 7270
COQ2 7254
IDI1 7247
PSMD1 7241
HSD17B12 7181
PLD2 7180
RPL26L1 7176
PSMB3 7171
SPR 7165
GYS1 7157
PSAP 7145
CSAD 7121
AZIN1 7119
RAB5A 7103
EXT1 7098
PSMA7 7096
RAB14 7095
PCBD1 7093
ELOVL1 7088
LRP10 7070
PPP1CB 7064
PSMC1 7021
NDUFAF3 6981
SDHD 6963
OSBPL8 6960
CBS 6946
ABHD3 6943
KYNU 6934
SLC22A5 6929
ME2 6915
UQCR11 6907
FECH 6882
INPP5A 6880
MAN2B1 6878
HACD4 6870
PNPLA6 6863
ITPK1 6851
CYP51A1 6844
TIMMDC1 6822
PCYT1A 6816
PSMB6 6813
RRM2B 6798
PYCR1 6789
TPI1 6786
PTDSS1 6778
UPB1 6772
GNPAT 6753
MED20 6743
PRKAR2B 6741
VKORC1 6728
PDSS2 6723
NAT1 6718
ST3GAL6 6701
SREBF2 6695
ATP5F1C 6687
DHCR7 6676
PSMF1 6659
UBB 6639
SDC4 6637
PSMC6 6635
COX8A 6611
SMS 6610
MGST3 6607
LMBRD1 6582
PSAT1 6580
CDS2 6557
PSMD12 6556
SERINC3 6548
SREBF1 6539
CPT2 6538
ATP5MF 6519
AOC1 6509
ADI1 6500
ATP5F1B 6497
GNG11 6495
NUDT19 6494
SAR1B 6479
RDH11 6466
ESD 6464
NDUFA4 6459
AHCYL1 6456
PIP5K1B 6450
OCRL 6442
ATP5F1A 6441
CMBL 6437
INSIG2 6430
ABHD4 6425
OSBPL9 6404
PSPH 6403
AOC2 6402
RUFY1 6399
SAMHD1 6397
CSNK2A2 6388
ATP5PF 6373
HPRT1 6371
NDUFS1 6348
CES2 6341
SMOX 6332
PPP1CC 6330
CHST13 6326
UQCRFS1 6325
LRP12 6321
SYNJ1 6296
MMADHC 6291
ISCA1 6287
GPI 6284
CYP4F3 6259
UGCG 6247
PSMD11 6231
DBI 6227
CDIPT 6222
MED25 6209
COX5B 6207
CSNK2A1 6199
MTM1 6198
LDLR 6183
TCN1 6182
NDUFS5 6178
DEGS1 6169
COX5A 6168
PRKAR2A 6166
PPIP5K2 6151
PPCS 6144
ATP5F1E 6142
EHHADH 6140
EP300 6129
PIP5K1A 6110
ABCA1 6109
NDUFC2 6093
BCKDHA 6091
DNM2 6089
NDUFS2 6080
PGLS 6079
MED13L 6077
CHKA 6073
PIK3CD 6046
GDPD3 6027
FABP5 6021
ELOVL5 6011
NDUFA6 6009
ACOX3 5995
PSMA6 5970
ORMDL2 5967
PSMD7 5963
SUCLG1 5961
NT5M 5959
PDK4 5953
PSMD13 5948
ESRRA 5943
SGSH 5912
AFMID 5910
ATP5MC3 5906
NCOR1 5887
APOA2 5879
CPNE3 5872
B3GNT2 5868
PTDSS2 5867
UQCRC2 5852
PHYKPL 5845
PGM1 5843
ITPR2 5842
ASL 5839
ISCA2 5823
HMBS 5822
NDUFB10 5812
CERS6 5795
PITPNM1 5791
SERINC1 5786
ST3GAL4 5781
NCOA6 5773
BLVRA 5763
NDUFAB1 5759
PSMD8 5757
SEC13 5748
TPST2 5725
NDUFA1 5718
ABCC3 5717
NUDT3 5716
PLA2G12A 5705
PLAAT1 5692
TNFAIP8L2 5671
COX6B1 5667
COQ5 5633
ARG2 5626
NDUFA7 5623
RHCE 5621
B3GALNT1 5619
ADPGK 5602
STAB2 5569
G6PC 5568
GLUD1 5567
DHTKD1 5562
SYT5 5548
SLC35B3 5546
ACAT1 5542
ATP5MG 5512
MBOAT1 5500
AGPS 5495
SULT1A4 5483
MCAT 5450
ACOT9 5446
ACSM2A 5445
GSTZ1 5438
GUK1 5436
ACOT13 5423
RPS9 5421
AMPD2 5418
SDC2 5397
GCLM 5391
SUOX 5380
GCHFR 5356
HMGCL 5349
NDUFC1 5343
PSMA2 5339
FDPS 5335
B3GALT4 5332
SAT1 5327
RIDA 5326
ACACA 5315
DECR1 5313
DGAT1 5306
TKFC 5285
MED16 5278
ADCY4 5270
NUDT9 5244
HYAL3 5229
SLC3A2 5222
NDUFV3 5214
NME4 5208
ALDH1L2 5196
NFS1 5188
PIAS4 5184
DHFR 5167
RAE1 5164
ACLY 5159
GPX4 5150
OSBPL2 5117
HAGH 5104
PTGES 5102
COX6A1 5095
ADSL 5085
CPT1A 5077
CYP2C9 5042
MTHFR 5031
GALE 5026
ADIPOR2 5016
PIK3R2 5010
PLCG2 5006
ASRGL1 4994
CRYL1 4975
NDUFA2 4966
APIP 4962
SUMO2 4961
UROD 4960
SLC25A1 4955
ECSIT 4918
FUT1 4899
UCK1 4856
CHST11 4824
ACAD10 4823
AGPAT3 4809
STARD10 4808
NDUFA8 4804
ATP5PO 4794
FDXR 4766
PTGS2 4753
ACOXL 4749
HSD17B13 4718
SLC22A1 4716
COQ7 4706
HDAC3 4673
PLCB2 4665
SPTSSA 4652
TXN2 4651
TK1 4644
PIK3CA 4629
PSMD3 4618
KYAT3 4615
NSDHL 4594
PPP2R1A 4589
LRP8 4568
TBL1XR1 4556
MPC2 4555
NDUFB4 4553
HACD1 4548
FHL2 4524
HS6ST1 4523
NUP50 4521
RPL3L 4503
NUBP1 4501
NCOA1 4483
COX7B 4465
STS 4459
SLC16A1 4455
SCP2 4454
UBC 4439
NT5C3A 4437
TPMT 4422
OSBPL6 4419
NNT 4407
TACO1 4406
MED18 4396
MED26 4395
UQCR10 4378
PARP4 4362
SEM1 4348
VDAC1 4347
ACADS 4297
GNG8 4296
B4GALT1 4292
NDUFV2 4288
PDHX 4282
MAN2B2 4281
VKORC1L1 4256
GLYAT 4252
PDK1 4249
NDUFA13 4244
PDHB 4233
NDUFB6 4218
SQLE 4211
ACO2 4209
MDH2 4207
COX4I1 4191
HSD17B10 4182
GPAT4 4177
HYAL1 4164
NDUFS6 4155
OGDH 4136
PTGES3 4125
GSTM5 4119
CSGALNACT1 4102
HSD17B2 4085
PSMB2 4084
SULT1A3 4082
PPP1CA 4069
AOC3 4067
UGDH 4065
MAPKAPK2 4054
SCD 4026
IP6K1 4023
COQ10B 3989
PPARGC1A 3988
NDUFS4 3986
SRD5A3 3971
CSNK2B 3969
ALDH6A1 3964
SLC25A20 3958
G6PC3 3915
NDUFB5 3892
CYP27A1 3877
HSD11B2 3838
UQCRB 3834
ACSM6 3832
PLA2R1 3812
HMMR 3808
FABP2 3805
MED22 3802
MMUT 3791
RNLS 3723
MID1IP1 3706
HS2ST1 3691
CS 3688
ALB 3668
HSD17B1 3654
CPTP 3651
IMPAD1 3635
AKT1 3614
SEC24B 3608
AMD1 3599
CACNA1D 3582
CA2 3570
PRPS2 3562
NUDT18 3553
ERCC2 3547
LIPH 3546
AKR1B15 3541
MTHFD2L 3536
SURF1 3532
NCOA3 3522
NFYA 3506
RHD 3505
ARSA 3486
MOCOS 3461
PXMP2 3436
PSMD5 3426
CREBBP 3423
ACAA2 3421
PIP5K1C 3419
SLC6A12 3414
STARD7 3407
NADSYN1 3392
PSMB1 3374
RFK 3348
STARD3 3342
SGPL1 3332
GNAI1 3329
PGM2L1 3328
PMVK 3317
ACBD7 3315
IDH3G 3314
PHGDH 3301
IPPK 3279
ODC1 3266
GNA11 3259
PDK3 3252
MED19 3243
MED4 3215
PIKFYVE 3187
TMEM86B 3138
PEMT 3103
NUP98 3101
MED17 3084
TYMP 3083
TPH2 3082
NUP37 3074
CYC1 3047
NAGS 3032
SLC7A5 3012
GLB1L 2992
PANK3 2980
GBA2 2974
ATP5F1D 2968
MBTPS1 2966
UQCRQ 2960
ATP5MC2 2956
MTMR4 2951
PHOSPHO1 2944
HSCB 2935
ALDH9A1 2884
FH 2879
POMC 2855
SPHK2 2827
CA4 2826
DGUOK 2820
KCNB1 2784
TAZ 2754
NDUFAF7 2726
ABO 2725
SLC44A2 2700
DHCR24 2694
ATP5ME 2664
PSMD14 2611
SDC3 2599
PSMC2 2598
RPE 2589
AKR7A2 2568
MSMO1 2557
LPL 2545
MED13 2533
PSMB4 2523
ABCC5 2477
SMPD2 2476
NDOR1 2458
GLYATL2 2451
KPNB1 2430
PPP2R5D 2421
AK2 2414
SLC37A2 2350
CTPS2 2345
NDUFB7 2292
STK11 2289
ADRA2A 2271
GCAT 2234
TTPA 2230
PTPMT1 2213
VAPB 2194
PLPP2 2186
CIAO2B 2179
PLCH1 2174
INMT 2172
NDUFAF2 2133
NDUFS7 2118
PPA2 2096
SDSL 2091
ACER2 2074
RPS27L 2061
CBR1 2037
MED12 2034
GNMT 2027
PRKAG2 2015
MDH1 1995
MTRR 1994
PSMC3 1976
CAV1 1969
PPA1 1934
ENPP2 1925
GDA 1908
SLC46A1 1882
CCNC 1877
SPTLC3 1857
FDX1 1854
NME2 1850
PIK3CG 1833
SLC25A19 1785
NME1 1742
PIK3C2G 1737
UGT1A1 1670
PHKG2 1631
PIK3C3 1619
SLC16A8 1608
PSMD10 1559
HS3ST2 1510
CYP3A43 1492
FADS2 1486
MED31 1462
NDUFA11 1458
MTMR9 1453
AKR1A1 1447
RPIA 1441
HSP90AA1 1326
LRP2 1307
TECRL 1306
HEXA 1261
PTGR2 1238
CA13 1227
PLCB1 1197
GCK 1193
HTD2 1183
GSTM4 1181
NDUFB11 1172
CHST14 1138
PRKCA 1132
SMPD1 1129
CEPT1 1127
UBA52 1121
PRKD3 1104
NCOA2 1092
NUDT7 1086
B4GALNT2 1079
DARS1 1069
PLA2G4D 1068
ALDH7A1 1060
GRHPR 1030
NDUFB8 965
UCP2 913
GNG3 890
CSNK1G2 887
NDUFS3 884
MT-ND4 840
PLEKHA4 838
ALDH3A2 833
PPARA 813
DECR2 783
NUP62 769
TRMT112 738
GSS 715
NPAS2 712
COX6C 706
MT-CO1 684
ABCC1 576
COX7C 564
ADH1B 519
GNB5 512
ST3GAL3 505
NDUFA3 503
RETSAT 498
PYGB 492
ECI1 486
AKR1C1 473
AHCY 466
MT-ND6 459
TYMS 458
PGP 437
APOM 429
ASPA 427
RPS4Y1 424
B4GALT4 391
THRAP3 388
MTHFD1L 371
CACNB3 370
AACS 351
SLC25A16 348
GLDC 318
SLC25A21 305
WASL 299
AK9 259
MED7 224
APOE 218
POLD1 204
PANK1 195
FAHD1 174
TPO 148
GSTP1 135
COX16 132
ADCY9 123
QARS1 86
MBTPS2 83
NDUFS8 81
MT-CO2 48
MT-CO3 40
CYP1A2 38
RPL36AL 32
RPLP1 19
LHPP 11
FAM120B -8
AANAT -41
ENPP6 -56
FMOD -59
ABCG2 -77
VAC14 -124
GSTM1 -140
GADL1 -171
LCLAT1 -177
RRM2 -183
MED14 -203
HGD -235
PPP2R1B -241
IYD -255
RPS24 -263
DCXR -290
PPCDC -292
ACSF3 -347
LTC4S -353
FAU -362
FMO3 -371
SLC25A13 -412
AASDHPPT -458
TNFAIP8 -460
GRHL1 -492
PLAAT2 -544
MED11 -560
CYP46A1 -580
PSMA4 -616
CPOX -639
NME3 -652
PCK2 -685
IMPA1 -687
FASN -690
GGT5 -695
SHMT1 -717
ACADL -726
UBE2I -764
SLC27A3 -798
RANBP2 -820
ACOT11 -823
MED6 -842
PSMC5 -863
ACAD9 -879
GPS2 -889
PNMT -916
CYP4F8 -925
RPL15 -963
AIMP2 -988
RPLP0 -1000
PFKM -1014
GGPS1 -1066
BPNT1 -1073
MINPP1 -1095
MPC1 -1097
SULT1C2 -1102
RPL8 -1187
AUH -1196
AKR7L -1205
SERINC4 -1223
ACSBG1 -1236
CBR4 -1239
STAR -1244
ACBD5 -1284
CHST5 -1306
ACADM -1308
CYCS -1334
PLEKHA2 -1351
ETNK1 -1401
EXT2 -1405
MED28 -1429
RPS26 -1430
MOGAT3 -1460
RPL28 -1462
MIOX -1466
COX14 -1496
IDH3B -1504
CMPK1 -1520
GPT2 -1542
HILPDA -1566
ADCY6 -1608
RPL22L1 -1619
GSTK1 -1620
INPP1 -1654
DCTPP1 -1664
MTMR12 -1677
HACD2 -1711
DSEL -1727
NDUFA12 -1728
PRELP -1738
MARCKS -1739
PLEKHA6 -1745
RPS13 -1749
NUDT12 -1752
SLC10A1 -1762
ADO -1804
CHDH -1816
ISCU -1833
ABCB7 -1842
GSTM3 -1867
RPL9 -1872
SLC19A3 -1900
ACP5 -1920
RPL7 -1955
CDK8 -1971
HMGCS1 -1972
PTS -1981
INPP5K -2034
NOS3 -2059
EEF1E1 -2072
B3GAT2 -2076
ABCC2 -2079
CALM1 -2081
RIMKLA -2082
RPS8 -2083
MT-ATP6 -2096
DHFR2 -2143
GNG4 -2154
MT-ND5 -2166
MTMR2 -2216
AMDHD1 -2226
MT-CYB -2254
ECHS1 -2265
PIK3R5 -2304
MFSD2A -2309
OXCT2 -2322
ADK -2326
NDUFAF6 -2331
ACSM2B -2360
PIP4K2A -2365
GCDH -2370
GNB3 -2397
ALDOB -2431
ACMSD -2493
PYCR2 -2496
SHPK -2528
CERS5 -2540
LDHAL6A -2551
SEC24C -2569
MARS1 -2588
PI4KA -2601
IDS -2621
NMNAT3 -2629
OSBP -2645
CYP4F12 -2701
DPEP2 -2705
ARV1 -2720
SLC25A28 -2721
APRT -2766
PAPSS2 -2810
CERS3 -2840
CA6 -2843
PLA2G4C -2845
DNPH1 -2846
RPL27 -2855
HIBCH -2884
SLC26A2 -2893
DPEP3 -2894
ADCY2 -2896
RAPGEF3 -2911
B3GAT3 -2928
STARD5 -2943
BCAT2 -2962
NUDT15 -2973
DIO1 -2981
AK6 -2996
RPL39 -3006
NUP85 -3049
MT-ATP8 -3067
PSMB8 -3076
PLEKHA8 -3080
IDH2 -3102
NQO1 -3115
CPS1 -3132
AGL -3136
RBKS -3142
GSTO2 -3175
EPRS1 -3185
NAXE -3187
SRR -3203
PHYH -3231
SLC23A2 -3248
CACNA1A -3256
RXRB -3276
PFKL -3277
TPK1 -3279
ADCY7 -3286
ACOT7 -3289
RPL23 -3314
CHKB -3319
PNPLA4 -3322
RPL6 -3354
NUDT1 -3379
MTMR1 -3383
CDS1 -3388
CPNE1 -3397
PITPNM3 -3420
RPL13 -3431
ALDOC -3438
PPM1L -3445
ANGPTL4 -3469
HYKK -3495
THTPA -3512
PFKP -3517
DLAT -3526
SLC44A5 -3527
GPX2 -3533
NUDT5 -3557
MTMR7 -3565
AIP -3566
GART -3567
NMRK1 -3570
OSBPL10 -3580
RPL4 -3582
NR1H3 -3597
RPL29 -3611
SLC27A5 -3614
MT-ND1 -3616
PLA2G10 -3617
MT-ND3 -3649
SERINC5 -3658
RPL7A -3665
RPS15 -3673
NAALAD2 -3680
SC5D -3695
ACAT2 -3713
GLO1 -3721
CYP3A5 -3761
PLIN1 -3785
ACP6 -3790
MAN2C1 -3805
CYP27B1 -3807
CYP24A1 -3820
SLC27A2 -3831
NEU3 -3833
PLD6 -3870
GLYCTK -3936
RPL37A -3946
FA2H -3949
B3GNT3 -4017
MED1 -4036
INPP5D -4038
SULT1A2 -4046
STX1A -4052
PIK3R4 -4062
RPS21 -4079
STARD4 -4084
KCNJ11 -4105
SLC19A2 -4110
B3GALT1 -4134
KYAT1 -4140
CYP2S1 -4149
KDSR -4187
SCAP -4189
SIN3B -4205
PDP1 -4260
DDO -4276
GPC2 -4280
CYP7B1 -4294
HS3ST1 -4307
SLC23A1 -4335
CHST6 -4347
SCO2 -4351
SLC25A27 -4356
MAT2A -4359
AMN -4361
ISYNA1 -4370
PARP9 -4400
NDUFB2 -4446
OAZ3 -4447
PI4KB -4465
B3GALT6 -4474
RTEL1 -4476
RPS2 -4499
ACBD4 -4503
ACAD8 -4520
RPL31 -4541
CSPG4 -4549
GDPD1 -4554
PDHA1 -4581
CPT1B -4584
CHD9 -4585
ACY1 -4587
B3GALT2 -4595
ACOT1 -4622
GPC1 -4627
SLC25A14 -4642
LGMN -4644
RPS16 -4669
RPS3A -4694
RPS28 -4713
NDUFA5 -4723
MCEE -4724
XYLT2 -4727
RPL5 -4728
GPC4 -4730
RPL22 -4740
SLC25A12 -4760
NAGLU -4761
CIAO3 -4772
ARSG -4773
PYGM -4777
RARS1 -4794
ENTPD6 -4804
CNDP2 -4820
PITPNM2 -4822
INPP5F -4865
SHMT2 -4893
FAAH2 -4912
QDPR -4955
PARP6 -4959
PLEKHA5 -4963
RPS7 -4968
GPAT2 -4997
COX20 -5018
FDX2 -5019
PPARGC1B -5047
PLEKHA3 -5068
RPL18 -5080
FAAH -5096
SLC52A2 -5125
PIK3C2A -5194
GNG7 -5198
ADHFE1 -5216
UGT8 -5219
CERK -5241
PSMA3 -5285
RPL36 -5287
SLC5A5 -5330
FOLR2 -5337
CERS4 -5342
PAICS -5367
CA14 -5373
KARS1 -5382
GMPS -5430
RPL17 -5431
ABCB4 -5440
TGS1 -5441
NUDT13 -5444
RPS14 -5463
MED30 -5484
DBT -5509
FUT10 -5523
CYB5A -5527
LPIN3 -5536
ARSJ -5542
NUP42 -5564
SDHA -5579
HSD17B3 -5592
AGMAT -5600
NHLRC1 -5628
SLC5A6 -5629
DHODH -5633
B4GAT1 -5642
RPS5 -5691
PLPP1 -5711
PSMB10 -5735
RPS15A -5742
D2HGDH -5760
AHRR -5763
PLA2G2D -5777
SUCLG2 -5783
MTAP -5790
RPS10 -5793
RPL24 -5799
OSBPL1A -5816
SLC37A1 -5819
IDUA -5830
RPL38 -5840
TRIB3 -5843
MVD -5850
COX10 -5873
CKMT2 -5893
AIMP1 -5902
PRXL2B -5905
SARS1 -5909
ACSL6 -5913
RPS3 -5914
MED21 -5937
MIGA2 -5952
ORMDL1 -5954
NT5E -5964
IDO2 -5968
LIAS -5976
UCKL1 -5984
RPS12 -5987
LYRM4 -6003
CACNB2 -6006
RPL35A -6015
FTCD -6024
B4GALT2 -6034
DUT -6046
FITM2 -6050
PSMA5 -6053
STXBP1 -6059
SEH1L -6069
RPL18A -6070
PSME4 -6087
COX18 -6126
PON2 -6147
RPS6 -6160
ENTPD5 -6179
HAS3 -6197
MRI1 -6213
FITM1 -6244
RPS17 -6247
RPL27A -6257
AKR1C2 -6258
RPL11 -6261
RPL19 -6281
RPS4X -6285
PDZD11 -6288
RPS23 -6292
SDS -6313
NUP153 -6321
RPSA -6323
SLC37A4 -6333
AMT -6359
RPS25 -6365
RPL37 -6375
PPARD -6394
PNPO -6419
LARS1 -6428
ENTPD4 -6452
ZDHHC21 -6453
RPL21 -6458
GGCT -6517
RPL10 -6534
ABHD10 -6541
MT-ND2 -6560
RPL26 -6612
PI4K2A -6666
KMO -6673
PLA2G4B -6679
RPL10A -6686
SLC52A1 -6687
PLAAT3 -6706
RPL32 -6709
RPL14 -6710
MOCS3 -6731
ELOVL4 -6768
MED23 -6787
RAN -6791
RPL34 -6802
PLCE1 -6806
ARNTL -6811
PIPOX -6812
NOSIP -6827
CHAC2 -6837
GATM -6852
HSP90AB1 -6863
RPL41 -6866
MMACHC -6876
PNPLA7 -6877
AS3MT -6880
COX19 -6882
GPD1 -6895
SLC35D1 -6904
NMRAL1 -6922
PTGES2 -6926
LPIN2 -6935
RPS27A -6938
RPS19 -6965
AMACR -6980
NDUFA10 -6994
ENO3 -7018
RPL30 -7020
INPP5B -7024
TPR -7028
GPHN -7047
PITPNB -7049
RPL12 -7053
GAMT -7054
CPNE7 -7075
RPLP2 -7087
NADK2 -7146
SRM -7175
POM121C -7188
KHK -7193
RPS11 -7243
CYP2J2 -7268
DMAC2L -7274
MIGA1 -7300
PDPR -7326
MOCS1 -7346
MECR -7348
B4GALT7 -7367
ALOX12B -7374
RPL36A -7376
MED24 -7387
ACSM3 -7398
XYLT1 -7401
CEMIP -7418
LPCAT1 -7428
GCH1 -7439
ST3GAL1 -7442
CLOCK -7460
TM7SF2 -7470
CUBN -7513
PSMA8 -7606
ATP5MC1 -7616
ITPR1 -7629
GLS2 -7702
SULT2B1 -7719
RPS18 -7744
SCD5 -7756
NUP133 -7762
NAXD -7769
ACY3 -7770
HSPG2 -7779
PIP4K2B -7788
GNG2 -7795
ACER1 -7850
MMS19 -7874
CIAPIN1 -7893
UGT2B11 -7930
RPS29 -7940
PCCB -7976
MED29 -7985
PDK2 -8047
ADH5 -8056
LIPT2 -8065
RPL35 -8092
HS3ST3A1 -8096
COQ9 -8169
PRKAB2 -8172
SLC26A1 -8174
CTH -8181
NT5C1B -8182
NRF1 -8183
TSTD1 -8195
RPL13A -8212
HDC -8229
ADCY5 -8235
SCLY -8248
THEM5 -8249
GCSH -8292
POM121 -8299
CYP2D6 -8301
MVK -8305
FLVCR1 -8306
ASNS -8316
TMEM126B -8346
ITPA -8350
INPP5E -8363
AAAS -8389
PFKFB1 -8393
FLAD1 -8399
PARP10 -8400
PARP8 -8409
GSTA4 -8414
ABCD4 -8420
CBR3 -8424
PHKG1 -8428
LPCAT4 -8430
HIBADH -8435
HS3ST3B1 -8469
PRKG2 -8477
NUP54 -8479
ENO2 -8498
SYNJ2 -8511
SLC25A15 -8540
RPL3 -8561
AGPAT4 -8576
MED10 -8579
GGT7 -8598
PANK4 -8608
TPH1 -8640
PCCA -8664
GNPDA2 -8678
PLCD1 -8685
BPHL -8708
DCK -8733
BCO2 -8744
GPT -8754
ADPRM -8782
B4GALT6 -8785
CHST7 -8793
RPL39L -8805
MED9 -8812
PEX11A -8816
SPTSSB -8818
PRKD2 -8834
NDUFA9 -8864
RPS20 -8886
INPP4B -8893
DLST -8906
CES3 -8917
CYP2A6 -8965
CYSLTR2 -8970
MCCC1 -8976
NR1D1 -8980
SARDH -9008
HELZ2 -9045
MMAB -9046
HSD17B7 -9066
DBH -9067
ETNK2 -9115
PSMC4 -9127
MED27 -9191
GALT -9201
ASAH2 -9218
PRODH -9223
AK1 -9234
SACM1L -9235
LIPE -9245
IDH3A -9280
CYP4V2 -9298
PODXL2 -9309
MOCS2 -9331
SGPP2 -9332
NT5C -9361
CYP2E1 -9363
DTYMK -9425
TECR -9426
NUBP2 -9439
COQ3 -9453
FUT2 -9498
NDUFAF5 -9499
PIK3R1 -9505
NUP43 -9517
ACSM1 -9529
SLC25A32 -9560
RPL23A -9567
MLYCD -9599
INPP4A -9634
MORC2 -9637
AASS -9645
IDO1 -9680
ENPP1 -9700
CD320 -9704
RPS27 -9756
CAD -9762
MED15 -9778
GOT2 -9804
ABHD14B -9811
SCO1 -9819
GSTM2 -9892
L2HGDH -9902
PM20D1 -9905
EPHX1 -9912
IMPDH2 -9916
CYP2R1 -9918
AGPAT5 -9925
TNFAIP8L1 -9931
LDHB -9933
ACACB -9957
PTPN13 -9962
NFYB -9964
CIAO1 -9982
PSME1 -9991
ORMDL3 -9997
AK5 -10019
MTMR8 -10026
EEFSEC -10030
ME3 -10048
NDUFAF4 -10063
LRPPRC -10081
ACOT2 -10127
CTPS1 -10133
UCK2 -10134
IL4I1 -10164
DCTD -10167
XYLB -10178
EPHX2 -10186
PSTK -10190
ACAD11 -10194
UCP3 -10214
FABP3 -10221
SLC35B2 -10225
B3GNT4 -10231
NUP155 -10233
SLC25A10 -10239
GPAM -10241
ENOPH1 -10278
ITPR3 -10308
SECISBP2 -10334
PSME2 -10336
MAT2B -10365
CHPF -10383
PLPP6 -10392
ACADSB -10412
BDH1 -10419
NUP107 -10421
UMPS -10474
GPD1L -10479
PRSS1 -10480
SIN3A -10493
ACSL5 -10518
SBF1 -10530
CARNS1 -10534
NUP160 -10557
UBIAD1 -10558
SLC25A17 -10559
LSS -10583
NUP35 -10611
INSIG1 -10636
FPGS -10644
IP6K2 -10651
ALOX15 -10676
CARNMT1 -10722
HSD17B8 -10724
NUP210 -10726
B3GAT1 -10732
ACOT4 -10733
CA5B -10735
GDPD5 -10745
EPM2A -10751
B4GALT3 -10759
TRAP1 -10796
SELENOI -10809
NUDT11 -10835
RIMKLB -10844
HACD3 -10864
PAOX -10870
CACNA1C -10875
ALDH1B1 -10876
PTGDS -10886
ENPP3 -10948
TIAM2 -10979
PPIP5K1 -10998
PFAS -11033
DEGS2 -11048
DUOX1 -11054
PLCD4 -11061
THEM4 -11069
ACBD6 -11092
ALDH18A1 -11103
RRM1 -11119
PLCG1 -11120
CTRC -11123
PPAT -11159
ARSK -11166
CYB5B -11192
ATIC -11196
AZIN2 -11224
CHST2 -11228
PDP2 -11231
ADAL -11234
SLC2A1 -11236
PPOX -11262
ACSF2 -11266
PIK3C2B -11281
SEPSECS -11289
LIPT1 -11308
N6AMT1 -11314
NUP205 -11321
PSMB9 -11324
PPT2 -11340
PCYT2 -11345
PIP4K2C -11371
BCKDHB -11373
NUP88 -11397
COQ10A -11405
HADH -11421
LPIN1 -11437
MTHFD1 -11451
NDUFV1 -11466
ELOVL6 -11474
MMAA -11476
BDH2 -11480
UROS -11504
ITPKB -11506
FXN -11511
COX11 -11539
BRIP1 -11605
TSPOAP1 -11608
DDHD1 -11616
NUP93 -11620
NUP188 -11624
NUBPL -11628
ESYT2 -11660
GCLC -11691
OXCT1 -11698
HLCS -11710
GOT1 -11715
COQ6 -11716
UST -11728
OSBPL7 -11742
SMPD4 -11747
HACL1 -11751
ALDH1A1 -11765
ECI2 -11768
AGRN -11770
VAMP2 -11779
DDHD2 -11818
HMOX2 -11819
PARP16 -11830
PLCH2 -11831
CACNA2D2 -11844
PPM1K -11852
MCCC2 -11857
GLS -11862
PARP14 -11869
IARS1 -11897
AKR1B1 -11917
PRKACB -11959
OSBPL3 -11960
CD38 -11970
CROT -11973
RORA -11979
PI4K2B -11980
MTR -11996
NAT8L -11999
CYP2U1 -12000
PIK3R3 -12015
EBP -12029
SUMF2 -12038
ACSS1 -12065
CKB -12070
PRPS1 -12077
ST6GALNAC6 -12085
GNGT2 -12086
AKR1C3 -12104
QPRT -12106
AGK -12120
PLA2G6 -12122
PLEKHA1 -12149
BTD -12170
NDC1 -12173
OSBPL5 -12194
FUT11 -12201
SGPP1 -12210
ABCB1 -12224
PLAAT4 -12230
SMPD3 -12234
ESYT1 -12237
TNFRSF21 -12254
IVD -12260
CYP4F22 -12271
ADA -12297
B3GNT7 -12298
AKAP5 -12326
PLD4 -12365
CHST12 -12372


Platelet activation, signaling and aggregation

Platelet activation, signaling and aggregation
829
set Platelet activation, signaling and aggregation
setSize 221
pANOVA 1.35e-20
s.dist 0.363
p.adjustANOVA 2.05e-18



Top enriched genes

Top 20 genes
GeneID Gene Rank
F5 9485
CYB5R1 9460
GNA15 9452
CD36 9444
CLU 9371
GNG10 9349
APLP2 9347
GRB2 9304
QSOX1 9298
CD63 9287
ALDOA 9249
LHFPL2 9224
FERMT3 9223
PLA2G4A 9180
APP 9177
SERPINA1 9168
MAPK14 9104
ACTN1 9094
SYK 9076
PIK3CB 9038

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
F5 9485
CYB5R1 9460
GNA15 9452
CD36 9444
CLU 9371
GNG10 9349
APLP2 9347
GRB2 9304
QSOX1 9298
CD63 9287
ALDOA 9249
LHFPL2 9224
FERMT3 9223
PLA2G4A 9180
APP 9177
SERPINA1 9168
MAPK14 9104
ACTN1 9094
SYK 9076
PIK3CB 9038
STXBP2 9035
PRKCD 9008
GNAQ 8993
MAPK3 8953
CLEC1B 8931
CRK 8906
ITGA2B 8893
F13A1 8876
HGF 8863
TOR4A 8861
VTI1B 8850
GNG5 8815
RAC1 8793
LAMP2 8786
SRGN 8761
APBB1IP 8744
TIMP1 8677
TLN1 8525
ARRB2 8490
RHOG 8487
CLEC3B 8480
SELP 8457
RHOA 8319
GNB1 8294
ITGB3 8291
FN1 8284
SYTL4 8256
ANXA5 8210
CFL1 8186
EGF 8179
GNB2 8141
FCER1G 8131
CAP1 8111
GNAI2 8075
GAS6 8063
LY6G6F 8023
ORM1 7971
DGKG 7958
GNAI3 7953
VAV1 7896
CALU 7894
RAF1 7879
PECAM1 7855
P2RY1 7852
LYN 7809
SCCPDH 7787
PROS1 7758
MMRN1 7714
MGLL 7694
CDC42 7537
GP9 7506
MAPK1 7493
SERPINE1 7483
GP1BB 7470
VEGFA 7467
ABCC4 7434
STXBP3 7424
TAGLN2 7367
SPARC 7339
GNB4 7336
VCL 7328
RAP1A 7305
PIK3R6 7270
PSAP 7145
PRKCB 7097
HSPA5 7029
F8 7022
WDR1 6976
VEGFC 6906
GP6 6818
VWF 6641
GNG11 6495
TUBA4A 6484
GTPBP2 6331
TMSB4X 6295
GP1BA 6279
PDPK1 6136
PTPN6 6096
PPBP 6042
THBS1 5951
CD9 5940
ITPR2 5842
GNA13 5836
DAGLB 5820
PTPN1 5722
PF4 5707
YWHAZ 5624
A1BG 5559
PFN1 5459
PHACTR2 5410
PTPN11 5314
PDGFA 5293
CSK 5219
ECM1 5176
RAC2 5163
TGFB1 5153
TBXA2R 5148
ACTN4 5049
PIK3R2 5010
PLCG2 5006
OLA1 4914
VAV3 4894
P2RY12 4821
F2RL3 4773
PIK3CA 4629
PTK2 4462
CD109 4316
GNG8 4296
SHC1 4161
ALB 3668
AKT1 3614
RAB27B 3386
GNA12 3367
ENDOD1 3361
GNAI1 3329
TIMP3 3296
GNA11 3259
RAP1B 3206
CHID1 2811
MPL 2634
MANF 2550
ADRA2A 2271
PLEK 1999
ARRB1 1998
CFD 1984
PIK3CG 1833
APOOL 1609
GP5 1295
RHOB 1254
TTN 1195
PRKCA 1132
TF 1102
GNG3 890
STX4 606
GNB5 512
FLNA 483
DGKD -501
TMX3 -775
LCP2 -1156
TRPC6 -1935
PLG -1977
PCYOX1L -2009
CALM1 -2081
GNG4 -2154
F2RL2 -2284
PIK3R5 -2304
GNB3 -2397
ORM2 -2564
MAGED2 -2687
ABHD6 -2829
RAPGEF3 -2911
ITIH3 -3017
DGKH -3178
AAMP -3636
VAV2 -4055
SOD1 -4862
GNG7 -5198
DGKZ -5681
SOS1 -5700
ITIH4 -6208
SERPINF2 -6574
BRPF3 -6615
PPIA -6766
TGFB2 -7492
ITPR1 -7629
SELENOP -7771
GNG2 -7795
NHLRC2 -7835
TGFB3 -7891
VEGFB -7929
DGKA -7980
PRKCE -8001
DGKQ -8149
TEX264 -8366
CDC37L1 -8470
RASGRP2 -8529
PDGFB -8577
DAGLA -8578
SRC -8820
TRPC3 -9343
PIK3R1 -9505
F2R -9750
A2M -9870
FAM3C -10062
ITPR3 -10308
DGKK -10314
ABHD12 -10401
HABP4 -10921
CTSW -11117
SERPING1 -11197
DGKE -11390
LGALS3BP -11459
PRKCZ -11629
FYN -11675
LAT -11694
LCK -11838
RASGRP1 -11974
PIK3R3 -12015
GNGT2 -12086
PRKCQ -12127
PRKCH -12324


Signaling by Receptor Tyrosine Kinases

Signaling by Receptor Tyrosine Kinases
1131
set Signaling by Receptor Tyrosine Kinases
setSize 414
pANOVA 1.68e-20
s.dist 0.266
p.adjustANOVA 2.29e-18



Top enriched genes

Top 20 genes
GeneID Gene Rank
WASF1 9520
GRB10 9439
PRKACA 9429
ATP6V0A1 9423
LAMC1 9387
CTNNA1 9341
GRB2 9304
ATP6V1A 9302
DUSP3 9280
NCF4 9268
CYFIP1 9265
TNS3 9262
ATP6V0D1 9245
FES 9237
NCF2 9190
NCSTN 9186
ATP6V0C 9127
RIT1 9121
MAPK14 9104
FURIN 9075

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
WASF1 9520
GRB10 9439
PRKACA 9429
ATP6V0A1 9423
LAMC1 9387
CTNNA1 9341
GRB2 9304
ATP6V1A 9302
DUSP3 9280
NCF4 9268
CYFIP1 9265
TNS3 9262
ATP6V0D1 9245
FES 9237
NCF2 9190
NCSTN 9186
ATP6V0C 9127
RIT1 9121
MAPK14 9104
FURIN 9075
MAP2K1 9063
ATP6V1B2 9057
ATP6V1D 9047
PIK3CB 9038
CYBB 9031
PRKCD 9008
DLG4 9007
CLTC 9000
KL 8963
MAPK3 8953
CRK 8906
TGFA 8889
HGF 8863
MEMO1 8847
RAC1 8793
ADAM10 8791
FOSL1 8788
PCSK6 8740
AP2M1 8627
CDK5 8616
CDH5 8613
ATP6V0B 8598
ATP6V0E1 8596
IRS2 8569
SOCS6 8557
ATP6V1C1 8539
SPINT1 8446
RALB 8414
RNF41 8389
MAPKAPK3 8382
CLTA 8376
WASF2 8369
RHOA 8319
ITGB3 8291
INSR 8282
PPP2CA 8234
PAK1 8230
LYL1 8221
SPINT2 8206
PAK2 8185
EGF 8179
MKNK1 8170
ATP6AP1 8160
PTPN12 8151
ADAM17 8110
GAB2 8099
STAT3 8098
ATP6V1H 8064
EPN1 8045
ATP6V1E1 8035
AP2S1 8026
MEF2A 8009
PSEN1 7961
RAB4A 7941
PTK2B 7935
VAV1 7896
LYN 7809
PTPRJ 7783
PPP2CB 7712
RPS6KA1 7695
NCKAP1L 7673
SPHK1 7657
TRIB1 7643
SH3GL1 7625
PTPN2 7615
SH2B2 7609
POLR2E 7563
ADAP1 7557
TEC 7549
CDC42 7537
LAMB3 7497
MAPK1 7493
ROCK1 7489
CBL 7480
VEGFA 7467
NCKAP1 7462
FRS3 7343
SPARC 7339
NCF1 7334
DOCK1 7314
RAP1A 7305
AP2A2 7257
FLT3 7196
TCIRG1 7188
PRKCB 7097
ABI1 7082
SRF 7079
KIDINS220 7069
DNM3 7045
THBS3 7037
BRK1 7032
STAT5A 6965
TAB2 6964
SPRED2 6936
STAT5B 6925
CYBA 6922
VEGFC 6906
AP2A1 6832
WASF3 6808
JUNB 6806
MAP2K2 6794
FLT1 6793
GFAP 6713
POLR2J 6671
UBB 6639
AHCYL1 6456
USP8 6418
CTNNB1 6408
YWHAB 6385
APH1B 6280
ELMO1 6258
PXN 6230
NEDD4 6201
SH3KBP1 6173
STAM2 6159
PTPN18 6149
ROCK2 6138
PDPK1 6136
EP300 6129
ITGAV 6106
PTPN6 6096
DNM2 6089
SHB 6026
IGF1R 5990
PDGFC 5986
AREG 5977
LAMB1 5966
PTK6 5956
THBS1 5951
BAX 5916
NCOR1 5887
STAT6 5884
ATP6V1F 5878
PDGFRA 5858
ITPR2 5842
RANBP9 5813
PSENEN 5735
ATP6V1E2 5730
PTPN1 5722
ATF1 5706
GAB1 5679
FOS 5460
GTF2F2 5434
NRAS 5363
PTPN11 5314
POLR2L 5305
PDGFA 5293
PAG1 5268
CSK 5219
HNRNPM 5195
COL9A3 5126
MAPKAP1 5057
COL6A3 5053
HBEGF 5013
PIK3R2 5010
GTF2F1 4951
NCK2 4934
ID1 4927
VAV3 4894
PCSK5 4863
GRAP2 4690
PIK3CA 4629
POLR2F 4604
SGK1 4595
PPP2R1A 4589
HGS 4513
PTK2 4462
UBC 4439
ELMO2 4397
DUSP6 4357
SHC2 4183
ITGA2 4168
SHC1 4161
EPS15 4138
APH1A 4133
CDC37 4096
MAPKAPK2 4054
SHC3 3974
CRKL 3966
SOCS1 3947
MAP2K5 3940
ATP6V1G1 3931
HNRNPF 3929
FGF2 3920
SH2B3 3910
MAPK13 3865
MAPK11 3826
ANOS1 3822
GGA3 3816
NRG1 3750
KRAS 3702
EPS15L1 3655
AKT1 3614
DNM1 3587
POLR2G 3508
DNAL4 3398
ADORA2A 3293
RAP1B 3206
RAB4B 3137
EGR1 3124
RPS6KA2 3087
NTRK3 3068
RPS6KA3 2973
RALA 2710
JAK2 2691
EPGN 2662
HPN 2625
RANBP10 2553
PTPRO 2501
PPP2R5D 2421
SPRY1 2302
RASA1 2106
ATF2 2085
CAV1 1969
EREG 1888
HSPB1 1863
GALNT3 1805
FER 1761
IRS1 1741
MMP9 1690
PIK3C3 1619
POLR2C 1616
JUND 1549
ARF6 1377
FOSB 1368
NAB1 1342
HSP90AA1 1326
ITCH 1318
BRAF 1308
STAM 1285
VRK3 1281
PRKCA 1132
UBA52 1121
TF 1102
ELK1 1040
GABRG2 996
COL4A2 970
REST 865
MST1 849
CUL5 834
TIAM1 651
LAMB2 501
AKT2 433
POLR2I 396
MLST8 376
NELFB 374
APOE 218
TNS4 100
EGR3 44
PTPN3 -85
ITGB1 -94
PTBP1 -205
BAIAP2 -215
PPP2R1B -241
MEF2C -293
ERBB3 -472
ERBIN -574
DIAPH1 -854
STUB1 -1032
LAMA1 -1044
MAPK12 -1074
CDK5R1 -1089
TCF12 -1233
PLAT -1242
MAPK7 -1337
CREB1 -1378
EGR2 -1435
COL6A1 -1605
POLR2K -1783
NRG4 -1875
PLG -1977
GABRB3 -1992
LAMC3 -2016
NOS3 -2059
CALM1 -2081
ATP6V1C2 -2219
LAMA4 -2252
TIAL1 -2282
DOCK7 -2369
CHEK1 -2481
POLR2B -2523
AP2B1 -2709
PTPRU -2724
POLR2H -2942
POLR2A -3092
MEF2D -3094
DUSP7 -3211
LAMA5 -3263
FGFR4 -3293
HRAS -3382
FRS2 -3433
AAMP -3636
FLRT2 -3656
COL4A4 -3759
COL4A3 -3896
POLR2D -4024
VAV2 -4055
PIK3R4 -4062
PAK3 -4184
FGF7 -4247
NRP2 -4282
CHD4 -4515
ARHGEF7 -4583
SPRY2 -4603
DOCK3 -4640
ADAM12 -4744
TIA1 -5344
FGFR1 -5352
JUP -5353
S100B -5457
MST1R -5615
SOS1 -5700
PGF -5814
TRIB3 -5843
NCBP1 -5853
HNRNPA1 -5924
MUC20 -5962
TLR9 -5999
DUSP4 -6287
FGF23 -6622
RPS27A -6938
FLT4 -7216
PTPRK -7262
RBFOX2 -7280
ITPR1 -7629
PSEN2 -7718
VEGFB -7929
HNRNPH1 -7932
PRKCE -8001
NTRK1 -8193
THBS4 -8396
CTNND1 -8403
PDGFB -8577
FGF22 -8607
SPRED1 -8639
TPH1 -8640
STMN1 -8663
ESRP2 -8691
NRP1 -8717
FGF9 -8761
SRC -8820
CILP -8873
ESR1 -9122
FGFBP3 -9275
PIK3R1 -9505
ATP6V1G2 -9515
NCBP2 -9558
ID3 -9614
RICTOR -9670
MTOR -9767
COL9A2 -9770
RAPGEF1 -9826
FLT3LG -9894
LAMA2 -9911
WWP1 -10106
COL6A2 -10206
ITPR3 -10308
GRAP -10321
CYFIP2 -10367
LRIG1 -10389
NAB2 -10400
ITGA3 -10750
ABI2 -10915
ID2 -10969
KIT -11004
THEM4 -11069
WWOX -11085
PLCG1 -11120
MXD4 -11285
PDE3B -11322
NCK1 -11454
PDGFRB -11545
ATP6V0E2 -11555
RPS6KA5 -11594
PRKCZ -11629
FYN -11675
STAT1 -11727
FGFRL1 -11778
FGFR2 -11785
LCK -11838
AKT3 -11849
PRKACB -11959
PRR5 -11985
PIK3R3 -12015
RALGDS -12140
YES1 -12142
ATP6V0A2 -12211
FGFBP2 -12244
PDGFD -12247
MATK -12255
PTPRS -12291
ERBB2 -12320
AXL -12331
SH2D2A -12359


Signaling by Interleukins

Signaling by Interleukins
1102
set Signaling by Interleukins
setSize 386
pANOVA 1.71e-19
s.dist 0.268
p.adjustANOVA 2.12e-17



Top enriched genes

Top 20 genes
GeneID Gene Rank
CSF2RA 9526
S100A12 9515
VAMP7 9499
SOCS3 9476
TALDO1 9456
CCR2 9449
CD36 9444
SERPINB2 9438
PRKACA 9429
ITGAM 9398
VIM 9394
IL1RN 9381
CA1 9380
PTAFR 9355
NKIRAS2 9353
MAOA 9346
LMNB1 9345
GRB2 9304
FPR1 9295
DUSP3 9280

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CSF2RA 9526.0
S100A12 9515.0
VAMP7 9499.0
SOCS3 9476.0
TALDO1 9456.0
CCR2 9449.0
CD36 9444.0
SERPINB2 9438.0
PRKACA 9429.0
ITGAM 9398.0
VIM 9394.0
IL1RN 9381.0
CA1 9380.0
PTAFR 9355.0
NKIRAS2 9353.0
MAOA 9346.0
LMNB1 9345.0
GRB2 9304.0
FPR1 9295.0
DUSP3 9280.0
IL10 9272.0
TNFRSF1A 9270.0
IL17RA 9194.0
IL1R2 9188.0
APP 9177.0
BCL6 9175.0
IL10RB 9163.0
IRAK3 9107.0
MAPK14 9104.0
GSTO1 9084.0
SYK 9076.0
ARF1 9064.0
MAP2K1 9063.0
PIK3CB 9038.0
STXBP2 9035.0
INPPL1 9028.0
ALOX5 9001.0
HCK 8976.0
MAPK3 8953.0
ITGB2 8942.0
IL1R1 8917.0
CRK 8906.0
MAP2K6 8887.0
F13A1 8876.0
CCR1 8865.0
HGF 8863.0
CEBPD 8816.0
RHOU 8794.0
MAP2K3 8748.0
BCL2L1 8700.0
CSF3R 8687.0
FOXO3 8682.0
TIMP1 8677.0
TOLLIP 8572.0
IRS2 8569.0
ANXA2 8544.0
STX3 8492.0
PSMB7 8485.0
MAP3K3 8471.0
NOD2 8442.0
P4HB 8440.0
PSMD4 8402.0
MAPKAPK3 8382.0
LCP1 8381.0
PELI2 8314.0
SOS2 8299.0
FN1 8284.0
HMOX1 8278.0
PSME3 8251.0
PPP2CA 8234.0
JAK3 8219.0
CFL1 8186.0
PAK2 8185.0
PTPN12 8151.0
MYD88 8136.0
CAPZA1 8135.0
IL6R 8132.0
PSMB5 8101.0
GAB2 8099.0
STAT3 8098.0
MEF2A 8009.0
CHUK 7966.0
PTK2B 7935.0
VAV1 7896.0
PSMD6 7846.0
ANXA1 7842.0
LYN 7809.0
FSCN1 7794.0
OSM 7780.0
LCN2 7755.0
PELI3 7716.0
PPP2CB 7712.0
PIM1 7704.0
RPS6KA1 7695.0
CSF2RB 7661.0
PSMD9 7620.0
PTPN2 7615.0
TEC 7549.0
CDC42 7537.0
MAPK1 7493.0
CBL 7480.0
VEGFA 7467.0
HIF1A 7436.0
PSMD2 7411.0
IL18 7381.0
IL4R 7358.0
ITGAX 7337.0
PSMA1 7329.0
PSMD1 7241.0
PSMB3 7171.0
IL1RAP 7150.0
MCL1 7133.0
IL27 7120.0
PSMA7 7096.0
TYK2 7087.0
PSMC1 7021.0
STAT5A 6965.0
TAB2 6964.0
STAT5B 6925.0
MMP1 6891.0
MAP2K4 6866.0
PITPNA 6820.0
PSMB6 6813.0
NFKBIA 6807.0
JUNB 6806.0
PRTN3 6762.0
IL19 6757.0
PELI1 6715.0
PTPN9 6712.0
ICAM1 6705.0
H3C15 6699.5
PSMF1 6659.0
CNN2 6645.0
UBB 6639.0
PSMC6 6635.0
MUC1 6573.0
PSMD12 6556.0
BATF 6386.0
NFKB1 6277.0
PSMD11 6231.0
FBXW11 6196.0
MAP3K8 6160.0
PTPN18 6149.0
IRAK1 6131.0
PTPN6 6096.0
PIK3CD 6046.0
TNFRSF1B 6045.0
PSMA6 5970.0
PSMD7 5963.0
PSMD13 5948.0
STAT6 5884.0
CXCL1 5824.0
PSMD8 5757.0
ATF1 5706.0
TAB1 5681.0
UBE2V1 5637.0
YWHAZ 5624.0
TNIP2 5552.0
CANX 5528.0
MSN 5524.0
FOS 5460.0
CXCL2 5412.0
IKBKG 5377.0
PSMA2 5339.0
IL13RA1 5336.0
PTPN11 5314.0
TGFB1 5153.0
CTSG 5115.0
PIK3R2 5010.0
CISH 4915.0
CNTF 4845.0
IL1B 4807.0
PTGS2 4753.0
SMARCA4 4733.0
HAVCR2 4630.0
PIK3CA 4629.0
PSMD3 4618.0
PPP2R1A 4589.0
CDKN1A 4511.0
UBC 4439.0
SOD2 4390.0
DUSP6 4357.0
SEM1 4348.0
MAPK10 4325.0
SKP1 4287.0
CTF1 4260.0
CASP1 4224.0
SHC1 4161.0
PSMB2 4084.0
SQSTM1 4081.0
MAPKAPK2 4054.0
IL6ST 4025.0
IL18R1 3994.0
NDN 3968.0
CRKL 3966.0
SOCS1 3947.0
RBX1 3934.0
HNRNPF 3929.0
FGF2 3920.0
EBI3 3833.0
MAPK11 3826.0
BIRC5 3738.0
JUN 3722.0
TCP1 3660.0
AKT1 3614.0
IL27RA 3441.0
PSMD5 3426.0
HNRNPA2B1 3380.0
PSMB1 3374.0
TBK1 3229.0
RAP1B 3206.0
SOCS5 3184.0
IL1RL1 3175.0
TAB3 3160.0
RPS6KA2 3087.0
LGALS9 3016.0
RPS6KA3 2973.0
POMC 2855.0
RALA 2710.0
JAK2 2691.0
PSMD14 2611.0
PSMC2 2598.0
IL15RA 2585.0
PSMB4 2523.0
COL1A2 2469.0
PPP2R5D 2421.0
MAP3K7 2395.0
MYC 2304.0
OPRM1 2161.0
ATF2 2085.0
HSP90B1 2059.0
NANOG 2038.0
PSMC3 1976.0
UBE2N 1936.0
IRS1 1741.0
CXCL8 1729.0
MMP9 1690.0
MAP2K7 1654.0
PSMD10 1559.0
POU2F1 1537.0
HSP90AA1 1326.0
AGER 1294.0
VRK3 1281.0
BOLA2 1257.0
UBA52 1121.0
ELK1 1040.0
RIPK2 1025.0
IL18RAP 823.0
STX4 606.0
IL33 445.0
CSF1R 394.0
NKIRAS1 375.0
IL17RC 193.0
CD86 -14.0
ITGB1 -94.0
NFKBIB -152.0
TRAF6 -229.0
PPP2R1B -241.0
HMGB1 -252.0
MEF2C -293.0
PSMA4 -616.0
CASP3 -632.0
PSMC5 -863.0
RPLP0 -1000.0
NFKB2 -1165.0
PTPN23 -1186.0
MAPK7 -1337.0
CREB1 -1378.0
CRLF1 -1508.0
OSMR -1577.0
RELA -1803.0
TXLNA -1846.0
CSF1 -2061.0
PTPN14 -2386.0
SOCS2 -2538.0
CCL3 -3027.0
PSMB8 -3076.0
DUSP7 -3211.0
LAMA5 -3263.0
AIP -3566.0
PTPN20 -3783.0
MIF -3863.0
INPP5D -4038.0
STX1A -4052.0
FCER2 -4230.0
BCL2 -4704.0
OPRD1 -4782.0
SOD1 -4862.0
BTRC -4924.0
IL15 -5043.0
IGHE -5123.0
PSMA3 -5285.0
IKBKB -5386.0
CD4 -5406.0
IL17RE -5421.0
S100B -5457.0
SOS1 -5700.0
PSMB10 -5735.0
MTAP -5790.0
PSMA5 -6053.0
PSME4 -6087.0
IGHG1 -6201.0
DUSP4 -6287.0
IL17RB -6506.0
IL17C -6641.0
PPIA -6766.0
CD80 -6841.0
IGHG4 -6911.0
RPS27A -6938.0
CCND1 -6970.0
MAPK9 -7068.0
IL2RA -7161.0
BLNK -7227.0
TNF -7308.0
ZEB1 -7466.0
PSMA8 -7606.0
IL31RA -7636.0
IL12A -7823.0
CXCL10 -8160.0
IL7 -8554.0
RORC -8573.0
IFNLR1 -8808.0
CCR5 -8861.0
IL20RB -8921.0
IRF4 -8967.0
PSMC4 -9127.0
S1PR1 -9211.0
BRWD1 -9221.0
MAPK8 -9428.0
FOXO1 -9465.0
PIK3R1 -9505.0
IRAK2 -9548.0
IL16 -9726.0
IL11RA -9753.0
HSPA9 -9780.0
RAPGEF1 -9826.0
PTPN13 -9962.0
PSME1 -9991.0
SNRPA1 -10023.0
IL32 -10122.0
IFNG -10277.0
PSME2 -10336.0
IL4 -10399.0
IL23A -10538.0
IL7R -10546.0
IL18BP -10561.0
IL10RA -10594.0
STAT2 -10637.0
ALOX15 -10676.0
SIGIRR -10752.0
PTPN7 -10868.0
TP53 -10893.0
HSPA8 -10922.0
JAK1 -10955.0
CCL5 -10985.0
IL24 -11009.0
CLCF1 -11150.0
IL5RA -11211.0
HNRNPDL -11232.0
PSMB9 -11324.0
CUL1 -11330.0
RAG1 -11432.0
RPS6KA5 -11594.0
FYN -11675.0
STAT1 -11727.0
SMAD3 -11745.0
VAMP2 -11779.0
PDCD4 -11822.0
LCK -11838.0
CCL4 -11976.0
RORA -11979.0
IL12RB2 -11994.0
PIK3R3 -12015.0
IL2RG -12050.0
IL3RA -12057.0
IL12RB1 -12115.0
YES1 -12142.0
IL9R -12179.0
GATA3 -12191.0
PTPN4 -12220.0
IL21R -12256.0
NOD1 -12263.0
STAT4 -12336.0
CCL2 -12341.0
IL2RB -12347.0
FASLG -12371.0


Metabolism of proteins

Metabolism of proteins
649
set Metabolism of proteins
setSize 1719
pANOVA 1.86e-19
s.dist 0.131
p.adjustANOVA 2.12e-17



Top enriched genes

Top 20 genes
GeneID Gene Rank
CSF2RA 9526
ADAMTS2 9525
FAM20A 9524
PPARG 9522
CTSA 9514
VCAN 9505
NPL 9498
ASGR2 9487
F5 9485
BST1 9480
SOCS3 9476
RAB32 9463
RAB13 9440
CTSD 9433
FAM20C 9421
CPE 9420
FBXO9 9416
KIF13A 9413
FBXL5 9410
XRN2 9400

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CSF2RA 9526.0
ADAMTS2 9525.0
FAM20A 9524.0
PPARG 9522.0
CTSA 9514.0
VCAN 9505.0
NPL 9498.0
ASGR2 9487.0
F5 9485.0
BST1 9480.0
SOCS3 9476.0
RAB32 9463.0
RAB13 9440.0
CTSD 9433.0
FAM20C 9421.0
CPE 9420.0
FBXO9 9416.0
KIF13A 9413.0
FBXL5 9410.0
XRN2 9400.0
LAMC1 9387.0
CKAP4 9370.0
RHOT1 9367.0
RAB31 9356.0
SNCA 9354.0
ANPEP 9350.0
GNG10 9349.0
APLP2 9347.0
SNX3 9326.0
QSOX1 9298.0
FSTL3 9290.0
H2BC21 9283.0
TPST1 9251.0
MSRB1 9247.0
ATP6V0D1 9245.0
ASGR1 9212.0
PCSK9 9208.0
RAB3D 9207.0
UIMC1 9202.0
MITF 9193.0
CES1 9192.0
ARF4 9191.0
UBE2D1 9187.0
NCSTN 9186.0
APP 9177.0
KLHL2 9174.0
SERPINA1 9168.0
DCTN2 9157.0
SPTB 9154.0
VNN2 9153.0
CD55 9145.0
KDELR1 9142.0
ST6GALNAC3 9134.0
VNN1 9092.0
FURIN 9075.0
MSRB2 9067.0
ARF1 9064.0
RAB1A 9052.0
H2BC12 9051.0
PHC2 9043.0
LGALS1 9032.0
NEU1 9029.0
ACTB 9011.0
SUMF1 8991.0
CTSZ 8975.0
GBA 8969.0
HDAC4 8960.0
ALPL 8947.0
B3GNT8 8945.0
ERO1A 8943.0
PNPLA2 8939.0
TPP1 8936.0
RAB10 8926.0
NLRP3 8901.0
OS9 8898.0
TGFA 8889.0
RAD23B 8886.0
NUCB1 8883.0
IGFBP2 8856.0
GALNT14 8844.0
GALNT2 8843.0
CMAS 8839.0
B4GALT5 8830.0
NSF 8829.0
NUP58 8820.0
GNG5 8815.0
ADAM10 8791.0
ADAMTS3 8785.0
PCMT1 8779.0
ANK1 8771.0
EXOC6 8762.0
GSN 8749.0
RAB7A 8742.0
GLB1 8725.0
TGOLN2 8714.0
EDEM2 8704.0
USP3 8699.0
RNF146 8696.0
RAB11A 8688.0
TIMP1 8677.0
MGAT4B 8675.0
ST3GAL2 8669.0
B3GNT5 8666.0
H3-3A 8661.0
TUBB2A 8659.0
RAB5C 8655.0
UBE2D3 8640.0
FBXL19 8620.0
CDC34 8611.0
RAB2A 8604.0
CAPZA2 8597.0
FKBP8 8579.0
SIAH2 8578.0
NRN1 8565.0
SOCS6 8557.0
RNF135 8556.0
UBE2R2 8548.0
SERP1 8543.0
EDEM3 8538.0
TLN1 8525.0
SMAD1 8511.0
ARRB2 8490.0
PSMB7 8485.0
FKBP9 8475.0
ATF6 8464.0
PTEN 8460.0
NOD2 8442.0
P4HB 8440.0
ADORA2B 8437.0
DNAJC3 8435.0
PLAUR 8424.0
RAB34 8420.0
RAB27A 8411.0
PSMD4 8402.0
DCTN4 8387.0
GCNT1 8379.0
TNIP1 8378.0
COPA 8366.0
RAB20 8351.0
MRTFA 8350.0
VDR 8348.0
DCAF6 8336.0
AGTPBP1 8330.0
RHOA 8319.0
RAB1B 8313.0
FUCA2 8304.0
GNB1 8294.0
ACADVL 8290.0
TXN 8285.0
FN1 8284.0
UBE2J2 8268.0
PSME3 8251.0
KIF5B 8239.0
ST8SIA4 8236.0
TRIM25 8226.0
GALNT7 8224.0
RAB40C 8215.0
TGFBI 8211.0
C1GALT1C1 8153.0
RAB6A 8148.0
TRIM27 8142.0
GNB2 8141.0
CAPZA1 8135.0
RAB3A 8133.0
SEC24D 8115.0
PSMB5 8101.0
STAT3 8098.0
ANKRD9 8085.0
GNAI2 8075.0
GAS6 8063.0
ATP6AP2 8034.0
EIF4G1 8031.0
RPN1 8024.0
CAPZB 8015.0
H2BC5 8003.0
CEBPB 7997.0
NCOR2 7985.0
COMMD9 7967.0
LTBP1 7962.0
NANS 7957.0
GNAI3 7953.0
TMED7 7950.0
RAB4A 7941.0
H2AC6 7934.0
JOSD2 7931.0
UBE2W 7929.0
MAN1A1 7927.0
NUP214 7921.0
SEC11A 7920.0
RNF7 7913.0
H2BC11 7912.0
FSTL1 7908.0
COPB2 7902.0
TTLL4 7901.0
CALU 7894.0
EPAS1 7886.0
ARF5 7885.0
NUS1 7864.0
WSB1 7862.0
VDAC2 7857.0
PSMD6 7846.0
DPH3 7837.0
USP4 7812.0
TRAPPC1 7806.0
RAB18 7801.0
CNIH1 7779.0
UBA3 7767.0
GSK3A 7760.0
PROS1 7758.0
MPDU1 7751.0
EIF4H 7750.0
WSB2 7743.0
DYNC1I2 7735.0
ARF3 7732.0
KDELR2 7728.0
ETFB 7688.0
UBE2H 7663.0
CSF2RB 7661.0
SEC24A 7660.0
SPHK1 7657.0
NFYC 7653.0
TOP1 7645.0
MBD6 7623.0
PSMD9 7620.0
ACTR10 7605.0
EXOSC4 7600.0
SPTA1 7595.0
COPG2 7594.0
EIF4A1 7590.0
PDIA5 7581.0
ARSB 7572.0
UBE2L3 7561.0
H2BC18 7547.0
USP10 7542.0
YOD1 7533.0
ADAMTSL4 7530.0
HNRNPK 7522.0
ELOC 7519.0
LRRC41 7515.0
H2AC11 7513.0
MRPL28 7510.0
COPG1 7509.0
PGA3 7501.0
FBXO7 7498.0
RXRA 7495.0
ELOB 7482.0
PGA5 7478.0
UBE2M 7477.0
CFP 7445.0
HIF1A 7436.0
ETF1 7419.0
NR1H2 7415.0
PSMD2 7411.0
FUCA1 7408.0
H2BC4 7389.0
MSRA 7382.0
ARSD 7365.0
AMFR 7363.0
PIAS1 7361.0
TADA3 7356.0
COMMD8 7353.0
UBE2F 7341.0
GNB4 7336.0
SEC23A 7335.0
PSMA1 7329.0
COPB1 7321.0
TUBA1A 7313.0
UBE2A 7309.0
MYDGF 7308.0
DCTN6 7300.0
CARS1 7297.0
H2BC17 7285.0
WIPI1 7277.0
RAB33B 7267.0
FPGT 7264.0
HDGF 7262.0
PSMD1 7241.0
TUBB4B 7240.0
SLC35A1 7225.0
CCT5 7220.0
MRPS36 7215.0
LYZ 7213.0
TUBA1C 7198.0
MELTF 7197.0
CARS2 7177.0
RPL26L1 7176.0
PSMB3 7171.0
TMED9 7167.0
STX5 7166.0
TFG 7160.0
RPN2 7140.0
CHCHD1 7129.0
MAVS 7124.0
TRAPPC3 7114.0
RAB39A 7113.0
TAF10 7110.0
RAB5A 7103.0
MCFD2 7099.0
PSMA7 7096.0
RAB14 7095.0
UBA1 7089.0
LMAN2 7080.0
HERPUD1 7077.0
GALNT4 7072.0
IDE 7051.0
CPM 7044.0
SUMO3 7042.0
PIGS 7033.0
HSPA5 7029.0
F8 7022.0
PSMC1 7021.0
SEC61B 7013.0
UBE2B 7003.0
ACTR1A 7002.0
MRPL23 6995.0
MRPL33 6993.0
GARS1 6990.0
TSPAN14 6971.0
TADA2B 6952.0
DYNC1LI1 6941.0
LMAN2L 6937.0
TUBA8 6933.0
DDOST 6931.0
RTN4RL2 6898.0
COPE 6896.0
MMP1 6891.0
SUMO1 6889.0
VCP 6886.0
UBE2K 6884.0
SEL1L 6847.0
PGA4 6836.0
CUL3 6821.0
PPP6C 6819.0
PSMB6 6813.0
NFKBIA 6807.0
DCP2 6804.0
RNF123 6802.0
SATB2 6781.0
WDTC1 6779.0
PPP2R5B 6774.0
UBE2E1 6759.0
XRCC4 6758.0
EIF2S3 6747.0
ST6GALNAC2 6746.0
ST3GAL6 6701.0
H3C15 6699.5
FBXO11 6698.0
MYO5A 6693.0
RAB5B 6690.0
GNAT2 6683.0
TDG 6672.0
PSMF1 6659.0
USP22 6652.0
MSRB3 6649.0
UBB 6639.0
PSMC6 6635.0
RNF40 6628.0
MAN2A2 6625.0
GORASP1 6606.0
PIGF 6597.0
SRP54 6591.0
COPS7A 6590.0
SSR1 6588.0
RENBP 6585.0
MUC1 6573.0
FBXW2 6560.0
PSMD12 6556.0
CCT8 6552.0
IGFBP7 6545.0
CCDC22 6533.0
SORL1 6530.0
RAB8B 6529.0
DCUN1D1 6523.0
BECN1 6516.0
RAD23A 6512.0
GALNT1 6508.0
GNG11 6495.0
RNF185 6491.0
TUBA4A 6484.0
NEDD8 6482.0
SAR1B 6479.0
GSPT1 6475.0
SEC61A1 6449.0
RAB43 6433.0
RARA 6429.0
PARK7 6421.0
USP8 6418.0
CTNNB1 6408.0
FOXO4 6391.0
CSNK2A2 6388.0
KBTBD7 6376.0
PREB 6368.0
CTSH 6360.0
CALR 6340.0
USP7 6323.0
SRP14 6320.0
LTF 6306.0
COL7A1 6304.0
APH1B 6280.0
TTLL7 6266.0
MGAT1 6257.0
BRCA1 6248.0
RRAGA 6244.0
TSTA3 6241.0
INO80C 6240.0
HNRNPC 6239.0
ATF4 6237.0
PSMD11 6231.0
ASB7 6221.0
GOLGA2 6203.0
CSNK2A1 6199.0
FBXW11 6196.0
EIF2S2 6175.0
TSPAN33 6170.0
RAB21 6165.0
STAM2 6159.0
USP15 6148.0
BRCC3 6145.0
COPS2 6139.0
EP300 6129.0
HDAC7 6122.0
ANO8 6099.0
RGS6 6086.0
HIPK2 6078.0
AURKAIP1 6074.0
EIF4EBP1 6072.0
NSMCE1 6056.0
RAB6B 6053.0
TMED2 6052.0
H2AZ1 6036.0
RNF181 6022.0
ZBED1 6017.0
COPS3 6005.0
DCTN3 5994.0
GPAA1 5992.0
ITM2B 5982.0
AREG 5977.0
PSMA6 5970.0
MRPL53 5968.0
LAMB1 5966.0
P2RY2 5965.0
PSMD7 5963.0
VNN3 5958.0
DYNLL1 5952.0
THBS1 5951.0
PSMD13 5948.0
SSR3 5935.0
CHST8 5900.0
DAD1 5895.0
PDIA6 5882.0
APOA2 5879.0
SEC22B 5873.0
COMMD1 5871.0
B3GNT2 5868.0
NSMCE2 5864.0
CD59 5859.0
BCL10 5849.0
IARS2 5821.0
ST3GAL4 5781.0
PSMD8 5757.0
SEC13 5748.0
ALG14 5746.0
PSENEN 5735.0
RNF20 5727.0
TPST2 5725.0
ADD1 5704.0
DNAJB11 5691.0
TUBB6 5685.0
TAB1 5681.0
EXOC1 5670.0
CETN2 5642.0
RAB36 5636.0
NTNG2 5601.0
EXOC4 5591.0
CTDSP2 5586.0
ARCN1 5580.0
OXA1L 5578.0
MIA2 5574.0
EXTL3 5561.0
TNIP2 5552.0
FBXL13 5534.0
CANX 5528.0
B3GNTL1 5520.0
TUBA1B 5509.0
TMEM115 5508.0
COMMD5 5497.0
FBXL4 5496.0
SP3 5490.0
TUBB1 5488.0
HDAC2 5482.0
AP3M1 5469.0
CEBPG 5466.0
USP9X 5464.0
CBX8 5448.0
RPS9 5421.0
NARS1 5415.0
PIGX 5399.0
SDC2 5397.0
H2BC9 5394.0
IKBKG 5377.0
RAB24 5354.0
TTLL12 5353.0
PABPC1 5351.0
MRPL30 5347.0
PSMA2 5339.0
TRAPPC9 5333.0
H2BC15 5312.0
TFPT 5309.0
STAG2 5301.0
WAC 5267.0
PPP6R1 5263.0
ZDHHC2 5254.0
TMEM132A 5245.0
VBP1 5239.0
GGCX 5237.0
TBCA 5235.0
COMMD7 5226.0
PRKCSH 5220.0
YKT6 5205.0
TRAPPC5 5191.0
PIAS4 5184.0
RAE1 5164.0
FEM1C 5160.0
METTL22 5157.0
TGFB1 5153.0
MTRF1L 5149.0
CCNE2 5143.0
CTSG 5115.0
KLHL5 5105.0
UBE2C 5101.0
UGGT1 5082.0
DCTN1 5078.0
KDM1B 5073.0
SRPRA 5058.0
KLHL21 5054.0
CDC73 5020.0
UBE2E3 5005.0
GCNT3 4996.0
SLC17A5 4989.0
USP12 4974.0
H2AC20 4972.0
SUMO2 4961.0
GMDS 4937.0
EXOC7 4924.0
DCAF10 4922.0
UBE2G1 4921.0
CISH 4915.0
DDIT3 4906.0
SMAD2 4905.0
KEAP1 4898.0
UGGT2 4897.0
ASB8 4884.0
MRPS5 4861.0
MRPL51 4848.0
FBXL20 4844.0
AR 4840.0
FBN1 4836.0
EIF4E 4813.0
MRPS10 4810.0
UBE2S 4746.0
AOPEP 4739.0
EIF3H 4729.0
EXOC3 4724.0
DPM2 4721.0
IKBKE 4715.0
SEC61G 4708.0
EIF3I 4700.0
BIRC2 4692.0
FBXO30 4683.0
HDAC3 4673.0
UBE2D2 4657.0
SEC16A 4619.0
PSMD3 4618.0
NRIP1 4609.0
PTRH2 4601.0
EIF3M 4580.0
MRPL44 4552.0
SUDS3 4526.0
NUP50 4521.0
HGS 4513.0
RPL3L 4503.0
FBXL15 4499.0
TUFM 4494.0
NCOA1 4483.0
C4A 4466.0
STS 4459.0
MRPS16 4452.0
SRP9 4444.0
UBC 4439.0
TPGS1 4435.0
FEM1B 4426.0
ING2 4415.0
RAB11B 4402.0
USP48 4399.0
KLHDC3 4392.0
KCTD6 4371.0
SPCS3 4370.0
COPS5 4361.0
SEM1 4348.0
VDAC1 4347.0
DCUN1D3 4333.0
CD109 4316.0
SP100 4314.0
FCGR3B 4313.0
MDM2 4312.0
RFT1 4309.0
RAB19 4300.0
GNG8 4296.0
DNMT3B 4294.0
B4GALT1 4292.0
SKP1 4287.0
SRP19 4280.0
EIF2S1 4279.0
COMMD10 4274.0
DYNC1LI2 4273.0
COG7 4269.0
HCFC1 4254.0
PEX5 4225.0
DYNC1I1 4187.0
PMM1 4176.0
SHC1 4161.0
USO1 4154.0
TRAPPC6B 4147.0
EXOC5 4141.0
NAPG 4139.0
APH1A 4133.0
PDIA3 4128.0
STT3A 4095.0
RAB9A 4088.0
PSMB2 4084.0
SULT1A3 4082.0
MRPL47 4077.0
MRPL58 4049.0
COPZ1 4035.0
SENP2 4030.0
FBXL8 4021.0
CDC20 3998.0
PPARGC1A 3988.0
RAB35 3981.0
SRD5A3 3971.0
CSNK2B 3969.0
TMEM129 3961.0
SSPO 3959.0
ADRM1 3953.0
RBX1 3934.0
RAB42 3932.0
TGFBR2 3914.0
GFM2 3905.0
SERPINA10 3902.0
LMNA 3887.0
GMPPA 3886.0
RAB8A 3880.0
OTOA 3867.0
MRPS34 3820.0
GGA3 3816.0
FN3K 3813.0
BIRC5 3738.0
ZRANB1 3730.0
ARFGAP3 3714.0
MRPL52 3707.0
VHL 3674.0
ALB 3668.0
PFDN5 3664.0
TCP1 3660.0
CLSPN 3640.0
BACE1 3609.0
SEC24B 3608.0
PFDN1 3598.0
PIGB 3580.0
MFGE8 3534.0
RTF1 3526.0
SCFD1 3525.0
KIN 3521.0
AGBL5 3518.0
RNF2 3513.0
METTL21A 3509.0
NFYA 3506.0
ARSA 3486.0
PAF1 3478.0
FBXO17 3474.0
MTFMT 3460.0
UBA6 3438.0
PSMD5 3426.0
CREBBP 3423.0
FFAR4 3410.0
RAB27B 3386.0
PSMB1 3374.0
KTN1 3363.0
FOXK2 3358.0
CTR9 3344.0
AURKA 3330.0
GNAI1 3329.0
ASB13 3324.0
ASB1 3319.0
FBXL18 3309.0
ADORA2A 3293.0
RNF152 3269.0
PPP6R3 3261.0
EIF2B2 3260.0
TUBB3 3242.0
APC 3240.0
INHBA 3227.0
SPCS2 3211.0
MRPL37 3208.0
COMMD2 3198.0
SOCS5 3184.0
NAGK 3158.0
ERCC8 3154.0
RAB4B 3137.0
SSR4 3135.0
DDA1 3127.0
PEX14 3125.0
MRPL13 3120.0
NUP98 3101.0
SENP8 3086.0
NUP37 3074.0
DDB1 3060.0
DERL2 3041.0
KLK2 3029.0
PIGZ 3026.0
SPCS1 3021.0
MBTPS1 2966.0
MUL1 2961.0
PEX2 2946.0
TARS1 2926.0
CDC25A 2911.0
GNAZ 2909.0
UBE2V2 2902.0
DOLPP1 2858.0
POMC 2855.0
TOPORS 2830.0
SSR2 2818.0
CUL4B 2802.0
MRPS35 2793.0
MTIF3 2791.0
TOP2A 2778.0
MRPS24 2777.0
TBCB 2776.0
ETFBKMT 2766.0
MRPS7 2753.0
SLC35C1 2750.0
MRPL45 2735.0
KBTBD6 2724.0
TMED3 2720.0
KHSRP 2714.0
EIF2B4 2707.0
SEMA5B 2706.0
ALG12 2659.0
RNF139 2627.0
EIF3D 2624.0
SAFB 2615.0
MAGT1 2613.0
USP49 2612.0
PSMD14 2611.0
PSMC2 2598.0
MBD5 2592.0
EIF3L 2579.0
DPM3 2577.0
PTP4A2 2561.0
MRPL12 2529.0
GCNT7 2527.0
CUL2 2526.0
PSMB4 2523.0
CFTR 2416.0
MAP3K7 2395.0
CSNK1D 2390.0
SPSB1 2374.0
FBXO40 2368.0
CTSC 2326.0
MLEC 2322.0
GGA1 2310.0
MYC 2304.0
CHM 2273.0
ADRA2A 2271.0
BTBD1 2263.0
CBX4 2222.0
CST3 2206.0
EIF5 2175.0
DPAGT1 2163.0
EIF3A 2145.0
MRPL18 2144.0
IGFBP6 2143.0
MT-RNR2 2112.0
PPA2 2096.0
RPS27L 2061.0
HSP90B1 2059.0
CCP110 2050.0
MRPL16 2042.0
MRPL36 2032.0
MBD1 2028.0
SRP68 2014.0
ARRB1 1998.0
PSMC3 1976.0
TUBA4B 1967.0
UCHL3 1959.0
LSAMP 1958.0
FCSK 1950.0
FEM1A 1947.0
UBE2N 1936.0
PPA1 1934.0
EIF3E 1915.0
EIF3J 1898.0
UBXN1 1892.0
FARSA 1876.0
ASXL2 1856.0
PIGN 1847.0
GALNT3 1805.0
MRPS22 1788.0
PIGQ 1782.0
COPS4 1776.0
MRPL22 1773.0
ZBTB17 1763.0
SFTPB 1754.0
CXCL8 1729.0
RAD21 1709.0
MRPS23 1699.0
GADD45GIP1 1697.0
PRMT3 1695.0
CCNA2 1685.0
ST8SIA5 1668.0
ALG6 1653.0
COPS6 1637.0
MGAT2 1633.0
STAMBP 1611.0
ATXN3 1601.0
ASB9 1587.0
TGFBR1 1585.0
DPM1 1567.0
PSMD10 1559.0
UBXN7 1556.0
CDK1 1540.0
KIFC3 1513.0
MRPS15 1487.0
EIF3K 1478.0
MRPS28 1464.0
NEGR1 1459.0
TSFM 1444.0
NAPA 1432.0
THRB 1429.0
MRPL15 1403.0
CCDC8 1402.0
OTUB1 1400.0
PMM2 1394.0
MRPS11 1391.0
KLHL9 1353.0
RTN4RL1 1345.0
ASB3 1325.0
STAM 1285.0
SHISA5 1269.0
SLC34A2 1253.0
EIF4B 1247.0
PFDN4 1163.0
BAP1 1126.0
UBA52 1121.0
TF 1102.0
SEC31A 1099.0
NCOA2 1092.0
PFDN2 1091.0
EIF1AX 1090.0
B4GALNT2 1079.0
DARS1 1069.0
RAB23 1046.0
RBBP5 1037.0
TSPAN5 1028.0
RIPK2 1025.0
FBXL3 1005.0
APEH 997.0
SYVN1 992.0
EIF3F 977.0
PIGT 952.0
MME 916.0
GNG3 890.0
EIF3G 878.0
GNAT1 877.0
DCUN1D5 861.0
USP30 856.0
ADAMTSL3 855.0
AURKB 846.0
CUL5 834.0
DNAJB9 820.0
PPARA 813.0
MRPL21 810.0
GALNT16 790.0
NUP62 769.0
MRPS18A 744.0
TRMT112 738.0
KLHL13 702.0
ZBTB16 689.0
CNIH2 654.0
HLA-B 649.0
POMT2 624.0
SMC1A 613.0
HDAC1 587.0
CCNA1 585.0
RAB44 573.0
PEX13 571.0
EIF5A 553.0
CAMKMT 550.0
YY1 537.0
CCT4 531.0
DHPS 525.0
GNB5 512.0
NR3C1 511.0
EXOSC3 509.0
ST3GAL3 505.0
LAMB2 501.0
MRPL19 452.0
IL33 445.0
VDAC3 436.0
DTL 428.0
RPS4Y1 424.0
B4GALT4 391.0
VCPKMT 334.0
SEC16B 330.0
TMED10 323.0
DPH5 315.0
EEF2 306.0
EIF3C 287.0
FBXW5 265.0
JOSD1 227.0
APOE 218.0
GALNT15 190.0
MRPS18C 181.0
USP25 173.0
KLF4 157.0
WDR5 155.0
QARS1 86.0
MBTPS2 83.0
WDR61 77.0
PIGM 62.0
LEO1 39.0
RPL36AL 32.0
RPLP1 19.0
EXOC8 -1.0
SLC30A6 -3.0
COG4 -6.0
TBC1D20 -18.0
B3GALNT2 -28.0
HYOU1 -113.0
EDEM1 -114.0
GOSR1 -182.0
CREBRF -188.0
YIF1A -225.0
TRAF6 -229.0
RWDD3 -238.0
RPS24 -263.0
VCPIP1 -268.0
MT-RNR1 -300.0
TTF1 -328.0
COG8 -346.0
FAU -362.0
MRPL20 -411.0
EIF2B1 -414.0
USP19 -456.0
SEC23IP -468.0
TNKS2 -499.0
ARL2 -565.0
PRSS21 -577.0
NPPA -584.0
BET1 -594.0
PSMA4 -616.0
ST6GALNAC4 -629.0
CCT6A -642.0
FBXO41 -657.0
OTULIN -683.0
MANEA -699.0
ALG5 -708.0
UBE2I -764.0
ICMT -786.0
RARS2 -790.0
GALNT6 -806.0
MTIF2 -809.0
EEF1D -811.0
RANBP2 -820.0
USP33 -821.0
RAB12 -856.0
PSMC5 -863.0
BABAM1 -897.0
PGM3 -906.0
USP34 -944.0
RPL15 -963.0
OTUB2 -980.0
GANAB -986.0
AIMP2 -988.0
MRPL3 -990.0
EXOSC1 -991.0
RPLP0 -1000.0
MRPL34 -1004.0
RAD52 -1021.0
WDR20 -1033.0
COMMD6 -1053.0
CREB3L2 -1143.0
GALNT5 -1162.0
NFKB2 -1165.0
TTLL2 -1171.0
RPL8 -1187.0
MDM4 -1230.0
ALG2 -1259.0
ALG3 -1263.0
FBXO15 -1269.0
DAP3 -1301.0
FBXL12 -1321.0
PDCL -1328.0
MRPL41 -1345.0
MAN2A1 -1349.0
PIAS3 -1358.0
COMMD3 -1363.0
EEF1G -1383.0
GAN -1414.0
RPS26 -1430.0
GOSR2 -1456.0
PIGC -1461.0
RPL28 -1462.0
BGLAP -1473.0
SRP72 -1491.0
CHML -1515.0
RAB7B -1531.0
MRPL57 -1540.0
ST6GAL2 -1541.0
CP -1561.0
XBP1 -1579.0
NR4A2 -1601.0
SLC34A1 -1602.0
RPL22L1 -1619.0
DOHH -1655.0
DCAF7 -1721.0
RPS13 -1749.0
RELA -1803.0
PIGV -1810.0
NICN1 -1831.0
CDCA8 -1838.0
RPL9 -1872.0
TSPAN15 -1876.0
MRPL4 -1883.0
POMK -1918.0
EEF1A1P5 -1925.0
SELENOS -1930.0
ARFGAP1 -1942.0
INO80B -1954.0
RPL7 -1955.0
MRPL54 -1962.0
SMC3 -1975.0
PLG -1977.0
ATXN7 -1983.0
PUM2 -2007.0
MAN1A2 -2055.0
CSF1 -2061.0
EEF1E1 -2072.0
CALM1 -2081.0
RPS8 -2083.0
MGAT4C -2109.0
KDELR3 -2117.0
GNG4 -2154.0
CXXC1 -2167.0
ASB14 -2170.0
MSLN -2192.0
MUCL1 -2211.0
DHDDS -2236.0
PFDN6 -2247.0
TRIM13 -2263.0
TRAPPC2L -2299.0
FBXO6 -2300.0
TTLL3 -2342.0
ENAM -2373.0
MGAT3 -2391.0
GNB3 -2397.0
CCT3 -2404.0
SUZ12 -2409.0
KAT2B -2414.0
DCAF11 -2444.0
SLC30A5 -2461.0
RABGGTA -2462.0
MRPL43 -2517.0
HIF3A -2519.0
SOCS2 -2538.0
CD52 -2561.0
SEC24C -2569.0
HLA-A -2573.0
MARS1 -2588.0
TAF9B -2599.0
MRPL14 -2647.0
RAB3B -2698.0
SERPIND1 -2722.0
TOP2B -2731.0
TOMM20 -2743.0
MRPL48 -2762.0
ASB6 -2763.0
NAPB -2780.0
CALB1 -2832.0
RPL27 -2855.0
NFRKB -2874.0
MUC6 -2977.0
SIAH1 -3000.0
MTA1 -3005.0
RPL39 -3006.0
B3GNT9 -3033.0
DNMT3A -3039.0
NUP85 -3049.0
MOGS -3051.0
MGAT5 -3072.0
MRPL27 -3073.0
PSMB8 -3076.0
NEURL2 -3097.0
CCT7 -3100.0
GALNT11 -3148.0
TPGS2 -3167.0
EPRS1 -3185.0
MUC4 -3191.0
COG5 -3259.0
RPL23 -3314.0
CUL7 -3334.0
TBCE -3336.0
GALNT10 -3341.0
RPL6 -3354.0
OBSL1 -3404.0
SKIV2L -3414.0
BARD1 -3419.0
RPL13 -3431.0
ADAMTS5 -3479.0
ZNF350 -3507.0
SPTBN5 -3531.0
THSD4 -3560.0
RPL4 -3582.0
DARS2 -3589.0
ALG11 -3593.0
NR1H3 -3597.0
RPL29 -3611.0
MRPS12 -3618.0
ALG8 -3635.0
DOLK -3639.0
MT-TV -3652.0
RPL7A -3665.0
RPS15 -3673.0
MARCHF6 -3678.0
NGLY1 -3686.0
FBXO22 -3709.0
PAPPA -3791.0
ADAMTS17 -3827.0
NEU3 -3833.0
PROZ -3872.0
CCDC59 -3900.0
NAT8B -3939.0
RPL37A -3946.0
MRPL11 -3948.0
USP47 -3954.0
RAB41 -3974.0
DYNLL2 -3980.0
B3GNT3 -4017.0
SPSB2 -4034.0
TNC -4039.0
STX1A -4052.0
RING1 -4063.0
TULP4 -4065.0
RPS21 -4079.0
BMP4 -4081.0
DCTN5 -4086.0
MUC16 -4104.0
POMGNT2 -4115.0
TTLL5 -4116.0
PCGF2 -4135.0
TTL -4136.0
YARS2 -4147.0
NAPSA -4183.0
RAB22A -4208.0
KBTBD8 -4224.0
SEC22C -4248.0
ARFGEF2 -4255.0
CREB3 -4257.0
EEF1B2 -4261.0
SMC6 -4277.0
UCN -4278.0
MDGA1 -4285.0
GBF1 -4290.0
C1GALT1 -4297.0
DIS3 -4322.0
RNF168 -4331.0
ADAMTS13 -4374.0
NR1I2 -4435.0
RAB26 -4448.0
SLC30A7 -4455.0
RPS2 -4499.0
GPS1 -4517.0
RNF103 -4536.0
RPL31 -4541.0
EXOSC5 -4577.0
MRPL35 -4593.0
MUC5B -4613.0
CBX2 -4617.0
COMMD4 -4618.0
ERAL1 -4628.0
TRAM1 -4636.0
EIF5B -4637.0
RPS16 -4669.0
RCE1 -4674.0
BLM -4690.0
RPS3A -4694.0
RPS28 -4713.0
RPL5 -4728.0
RPL22 -4740.0
ARSG -4773.0
LARGE2 -4786.0
RARS1 -4794.0
WARS2 -4809.0
CUL4A -4810.0
DCUN1D2 -4811.0
MAN1B1 -4871.0
ACTR8 -4894.0
ANK3 -4919.0
BTRC -4924.0
MRPS31 -4932.0
MRPS14 -4958.0
RPS7 -4968.0
SEC22A -5052.0
TRIM28 -5056.0
FOXK1 -5059.0
FBXO27 -5074.0
RPL18 -5080.0
EEF1A1 -5087.0
CRHR2 -5119.0
SPTBN2 -5129.0
OTUD5 -5132.0
EEF1A2 -5166.0
PIGP -5179.0
FUOM -5190.0
GNE -5192.0
GNG7 -5198.0
BTBD6 -5202.0
PARN -5224.0
INO80D -5234.0
CDKN2A -5236.0
RABGGTB -5240.0
USP14 -5246.0
TTLL11 -5257.0
TECTA -5268.0
PSMA3 -5285.0
GFM1 -5286.0
RPL36 -5287.0
ST6GALNAC1 -5314.0
FOLR2 -5337.0
GOLGB1 -5370.0
KARS1 -5382.0
COG3 -5426.0
RPL17 -5431.0
RPS14 -5463.0
RAB15 -5520.0
ARSJ -5542.0
NUP42 -5564.0
DCAF13 -5572.0
TRAF3 -5576.0
ASB4 -5604.0
MRPS17 -5606.0
PLA2G7 -5617.0
B4GAT1 -5642.0
MRPL1 -5678.0
MGAT4A -5680.0
MRPL40 -5682.0
RPS5 -5691.0
PSMB10 -5735.0
RPS15A -5742.0
LONP2 -5755.0
ARFGAP2 -5786.0
RPS10 -5793.0
RPL24 -5799.0
COG6 -5811.0
SCMH1 -5839.0
RPL38 -5840.0
MVD -5850.0
MRPL55 -5885.0
AIMP1 -5902.0
SARS1 -5909.0
LARGE1 -5910.0
RPS3 -5914.0
INCENP -5956.0
MUC20 -5962.0
PCNA -5969.0
RPS12 -5987.0
YARS1 -5991.0
PIGK -5994.0
RPL35A -6015.0
SPSB3 -6020.0
B4GALT2 -6034.0
PSMA5 -6053.0
USP5 -6068.0
SEH1L -6069.0
RPL18A -6070.0
PSME4 -6087.0
NUDT14 -6100.0
CUL9 -6106.0
VARS2 -6119.0
FBXL14 -6145.0
RPS6 -6160.0
TCF7L2 -6185.0
ACE -6215.0
DDX11 -6222.0
MRPS26 -6240.0
MIA3 -6245.0
RPS17 -6247.0
ANKRD28 -6250.0
RPL27A -6257.0
RPL11 -6261.0
DDX17 -6274.0
RPL19 -6281.0
RPS4X -6285.0
KLHL11 -6286.0
RPS23 -6292.0
MRPL24 -6300.0
NUP153 -6321.0
RPSA -6323.0
STAG1 -6347.0
RPS25 -6365.0
RPL37 -6375.0
LYPD5 -6380.0
THRA -6387.0
RNF5 -6413.0
FBXO10 -6427.0
LARS1 -6428.0
CTBP1 -6456.0
RPL21 -6458.0
GFPT1 -6462.0
UBA2 -6489.0
RPL10 -6534.0
RAB9B -6552.0
CAND1 -6554.0
H2BU1 -6555.0
PEX10 -6570.0
GGA2 -6587.0
MRPL38 -6596.0
FBXW7 -6600.0
RPL26 -6612.0
FGF23 -6622.0
PARS2 -6637.0
FBXL16 -6648.0
ASB16 -6665.0
PLA2G4B -6679.0
RPL10A -6686.0
SENP5 -6689.0
RPL32 -6709.0
RPL14 -6710.0
TRAPPC4 -6712.0
ADAMTS14 -6719.0
TRRAP -6722.0
USP13 -6737.0
RPL34 -6802.0
MAN1C1 -6804.0
ITIH2 -6820.0
GOLM1 -6842.0
MRPS2 -6844.0
RPL41 -6866.0
B2M -6920.0
RPS27A -6938.0
RPS19 -6965.0
USP21 -6972.0
RPL30 -7020.0
TPR -7028.0
RPL12 -7053.0
ADAMTS6 -7055.0
SMC5 -7084.0
RPLP2 -7087.0
OGT -7119.0
DPP4 -7125.0
CPA3 -7164.0
POM121C -7188.0
PIGA -7195.0
RPS11 -7243.0
MRPL2 -7263.0
THSD1 -7288.0
LYPD3 -7315.0
VARS1 -7323.0
GMPPB -7332.0
FBXW9 -7360.0
RPL36A -7376.0
DAG1 -7379.0
MYSM1 -7386.0
BET1L -7405.0
ST3GAL1 -7442.0
MRPL42 -7464.0
ACTL6A -7468.0
MXRA8 -7477.0
PIAS2 -7496.0
GPLD1 -7524.0
POLB -7537.0
NRN1L -7549.0
ENGASE -7552.0
WARS1 -7572.0
IGFBP4 -7582.0
PSMA8 -7606.0
TTLL1 -7612.0
LRR1 -7643.0
ALG13 -7645.0
APOL1 -7657.0
DYNC1H1 -7685.0
HARS2 -7708.0
GALNT9 -7716.0
RPS18 -7744.0
USP44 -7754.0
NUP133 -7762.0
SPTBN1 -7764.0
HSPG2 -7779.0
EXOC2 -7780.0
GNG2 -7795.0
UCHL5 -7861.0
GALNT8 -7869.0
SATB1 -7905.0
COG2 -7917.0
USP16 -7920.0
RPS29 -7940.0
ST8SIA1 -7949.0
INO80E -7964.0
SENP1 -7970.0
PIGG -8008.0
SBSPON -8022.0
UBE2G2 -8035.0
EIF3B -8059.0
ALG10 -8061.0
KLK1 -8081.0
RPL35 -8092.0
PHC3 -8152.0
AXIN2 -8154.0
RPL13A -8212.0
EIF2B3 -8218.0
ALG10B -8242.0
MCRS1 -8262.0
MRPL10 -8268.0
SKP2 -8279.0
SAE1 -8283.0
FARSB -8294.0
POM121 -8299.0
HARS1 -8314.0
ASNS -8316.0
ADAMTSL5 -8317.0
FBXO2 -8324.0
RECK -8343.0
SMAD4 -8351.0
FBXW12 -8358.0
KLHL42 -8367.0
SHPRH -8381.0
ADAMTS16 -8387.0
AAAS -8389.0
PHC1 -8402.0
MRPS30 -8413.0
DPH6 -8472.0
NUP54 -8479.0
TNIP3 -8502.0
TTLL13P -8507.0
MBOAT4 -8515.0
LARS2 -8516.0
MRPL50 -8537.0
MEN1 -8538.0
TOMM70 -8541.0
RPL3 -8561.0
THSD7A -8596.0
RUVBL1 -8612.0
FKBP14 -8631.0
POMT1 -8665.0
PML -8693.0
TRAPPC2 -8704.0
UBE2T -8710.0
RAB38 -8714.0
INO80 -8723.0
MRPS21 -8725.0
TNKS -8738.0
PEX12 -8753.0
COPS8 -8755.0
B4GALT6 -8785.0
PGAP1 -8788.0
ALG1 -8792.0
RPL39L -8805.0
AARS1 -8809.0
PIGO -8810.0
CCT2 -8825.0
KIF5C -8865.0
FARS2 -8867.0
KIF5A -8869.0
RPS20 -8886.0
MRPL46 -8897.0
DERL1 -8963.0
RAB2B -8982.0
MRPS27 -9001.0
SEC11C -9006.0
CNIH3 -9011.0
MRPL32 -9109.0
ESR1 -9122.0
PSMC4 -9127.0
TUBB4A -9162.0
MRRF -9198.0
PIGU -9200.0
FBXL22 -9210.0
AGBL2 -9212.0
NARS2 -9260.0
CCNF -9262.0
CBX5 -9272.0
WRAP53 -9335.0
CYLD -9359.0
TATDN2 -9360.0
TRAPPC10 -9369.0
AGBL3 -9406.0
SRPRB -9415.0
PIGH -9444.0
NANP -9448.0
TBCD -9449.0
IGFBP3 -9455.0
MRPS33 -9456.0
GHRL -9461.0
SEMA5A -9495.0
ERN1 -9501.0
NUP43 -9517.0
NPM1 -9532.0
RPL23A -9567.0
MRPL49 -9604.0
FBXO44 -9627.0
RGS9 -9636.0
GNPNAT1 -9662.0
DCAF5 -9664.0
ATF3 -9677.0
LMO7 -9709.0
GFPT2 -9713.0
CHD3 -9737.0
CREB3L4 -9751.0
FUT8 -9755.0
RPS27 -9756.0
ALG9 -9766.0
WFS1 -9774.0
COPS7B -9775.0
EIF2B5 -9809.0
BMI1 -9829.0
EXOSC6 -9839.0
DDX5 -9843.0
RAB30 -9844.0
EEF2KMT -9857.0
GALNT12 -9866.0
DCAF8 -9875.0
NR2C1 -9913.0
MRPS25 -9932.0
GNAO1 -9936.0
UHRF2 -9937.0
SPRN -9939.0
TUBA3D -9947.0
NOP58 -9951.0
NFYB -9964.0
PSME1 -9991.0
IGFALS -9994.0
DCUN1D4 -10001.0
FBXW8 -10013.0
TBCC -10066.0
PROC -10098.0
RAB29 -10185.0
USP37 -10210.0
PRKDC -10219.0
B3GNT4 -10231.0
NUP155 -10233.0
HIC1 -10249.0
EXOSC9 -10250.0
CASP8AP2 -10254.0
SPON1 -10262.0
AXIN1 -10285.0
ASXL1 -10309.0
PSME2 -10336.0
SMURF2 -10340.0
MAT2B -10365.0
GSPT2 -10403.0
NUP107 -10421.0
PTCD3 -10452.0
LMCD1 -10468.0
MRPL39 -10483.0
SIN3A -10493.0
NUP160 -10557.0
SARS2 -10572.0
DAXX -10575.0
AMDHD2 -10584.0
POFUT2 -10597.0
FBXO32 -10607.0
NUP35 -10611.0
STAMBPL1 -10617.0
NR3C2 -10625.0
LMAN1 -10630.0
EXOSC7 -10631.0
MRPS18B -10642.0
HERC2 -10658.0
KLHL25 -10671.0
MUC12 -10704.0
NUP210 -10726.0
MRPL9 -10743.0
DNAJC24 -10746.0
B4GALT3 -10759.0
MPI -10760.0
OTUD3 -10763.0
HLTF -10765.0
RCN1 -10766.0
L3MBTL2 -10770.0
KAT2A -10771.0
DPH7 -10779.0
FBXO21 -10790.0
SEC61A2 -10798.0
ERO1B -10822.0
GZMH -10827.0
ADAMTS4 -10829.0
MRPL17 -10860.0
COPZ2 -10863.0
TP53 -10893.0
UBE2Z -10912.0
TRAPPC6A -10917.0
HSPA8 -10922.0
NAE1 -10931.0
RAB33A -10940.0
TNFAIP3 -10950.0
MRPS6 -10988.0
TP53BP1 -10992.0
GCNT4 -10997.0
DPH2 -11005.0
STX17 -11006.0
LYPD2 -11013.0
ADAMTS10 -11036.0
OTUD7A -11041.0
EXOSC2 -11072.0
RIPK1 -11074.0
MRPS9 -11102.0
BIRC3 -11125.0
EXTL2 -11129.0
EIF4A2 -11157.0
RNF144A -11164.0
ARSK -11166.0
NSMCE4A -11187.0
ACTR5 -11217.0
FN3KRP -11220.0
CCT6B -11278.0
EIF2AK3 -11279.0
ZNF131 -11283.0
UBE2L6 -11293.0
USP24 -11306.0
DCAF4 -11310.0
N6AMT1 -11314.0
NUP205 -11321.0
PSMB9 -11324.0
CUL1 -11330.0
IFIH1 -11332.0
DPH1 -11342.0
DCAF17 -11365.0
USP42 -11367.0
TSPYL2 -11374.0
RAB40B -11375.0
NUP88 -11397.0
H2AW -11403.0
KLHL22 -11407.0
SPTAN1 -11426.0
ADAMTS1 -11438.0
MARS2 -11449.0
XPC -11450.0
EXOSC8 -11456.0
KLHL20 -11483.0
USP20 -11488.0
ST8SIA6 -11516.0
RAB39B -11529.0
DDB2 -11530.0
SFTPD -11535.0
KCTD7 -11546.0
UBE2Q2 -11554.0
WDR48 -11565.0
ST3GAL5 -11568.0
NUP93 -11620.0
NUP188 -11624.0
KLHL3 -11635.0
TARS2 -11669.0
CCNE1 -11707.0
PIGL -11711.0
DCAF16 -11717.0
RANGAP1 -11722.0
PIGW -11723.0
EIF5A2 -11741.0
SMAD3 -11745.0
TRAF2 -11746.0
NSMCE3 -11748.0
NOP56 -11750.0
ABCA3 -11756.0
FBXW4 -11757.0
B3GLCT -11758.0
PARP1 -11764.0
VAMP2 -11779.0
RAB37 -11793.0
AARS2 -11821.0
CHST10 -11841.0
FBXO4 -11843.0
EID3 -11870.0
SMAD7 -11872.0
ADRB2 -11892.0
IARS1 -11897.0
RAD18 -11916.0
GATA6 -11928.0
POMGNT1 -11937.0
DDX58 -11950.0
FBXO31 -11953.0
ASB2 -11978.0
RORA -11979.0
NUB1 -11986.0
RPA1 -12004.0
SUMF2 -12038.0
WRN -12047.0
ST6GAL1 -12052.0
MDC1 -12059.0
EARS2 -12069.0
ST6GALNAC6 -12085.0
GNGT2 -12086.0
OTUD7B -12095.0
COG1 -12125.0
XPNPEP2 -12151.0
RBBP7 -12155.0
UAP1 -12166.0
NDC1 -12173.0
GATA3 -12191.0
USP18 -12214.0
DNMT1 -12257.0
C3 -12262.0
NOD1 -12263.0
LY6E -12264.0
SPON2 -12276.0
PRSS23 -12288.0
B3GNT7 -12298.0
USP28 -12317.0
USP11 -12333.0
CCL2 -12341.0


Post-translational protein modification

Post-translational protein modification
841
set Post-translational protein modification
setSize 1194
pANOVA 5.6e-19
s.dist 0.153
p.adjustANOVA 5.87e-17



Top enriched genes

Top 20 genes
GeneID Gene Rank
ADAMTS2 9525
FAM20A 9524
PPARG 9522
CTSA 9514
VCAN 9505
NPL 9498
ASGR2 9487
F5 9485
BST1 9480
SOCS3 9476
RAB32 9463
RAB13 9440
FAM20C 9421
FBXO9 9416
FBXL5 9410
LAMC1 9387
CKAP4 9370
RHOT1 9367
RAB31 9356
APLP2 9347

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ADAMTS2 9525
FAM20A 9524
PPARG 9522
CTSA 9514
VCAN 9505
NPL 9498
ASGR2 9487
F5 9485
BST1 9480
SOCS3 9476
RAB32 9463
RAB13 9440
FAM20C 9421
FBXO9 9416
FBXL5 9410
LAMC1 9387
CKAP4 9370
RHOT1 9367
RAB31 9356
APLP2 9347
SNX3 9326
QSOX1 9298
FSTL3 9290
H2BC21 9283
TPST1 9251
ASGR1 9212
PCSK9 9208
RAB3D 9207
UIMC1 9202
MITF 9193
ARF4 9191
UBE2D1 9187
APP 9177
KLHL2 9174
SERPINA1 9168
DCTN2 9157
SPTB 9154
VNN2 9153
CD55 9145
KDELR1 9142
ST6GALNAC3 9134
VNN1 9092
FURIN 9075
ARF1 9064
RAB1A 9052
H2BC12 9051
PHC2 9043
LGALS1 9032
NEU1 9029
ACTB 9011
SUMF1 8991
CTSZ 8975
HDAC4 8960
ALPL 8947
B3GNT8 8945
PNPLA2 8939
RAB10 8926
NLRP3 8901
OS9 8898
TGFA 8889
RAD23B 8886
NUCB1 8883
GALNT14 8844
GALNT2 8843
CMAS 8839
B4GALT5 8830
NSF 8829
NUP58 8820
ADAM10 8791
ADAMTS3 8785
ANK1 8771
RAB7A 8742
GLB1 8725
TGOLN2 8714
EDEM2 8704
USP3 8699
RNF146 8696
RAB11A 8688
TIMP1 8677
MGAT4B 8675
ST3GAL2 8669
B3GNT5 8666
TUBB2A 8659
RAB5C 8655
UBE2D3 8640
FBXL19 8620
CDC34 8611
RAB2A 8604
CAPZA2 8597
FKBP8 8579
SIAH2 8578
NRN1 8565
SOCS6 8557
RNF135 8556
UBE2R2 8548
EDEM3 8538
SMAD1 8511
ARRB2 8490
PSMB7 8485
PTEN 8460
NOD2 8442
P4HB 8440
DNAJC3 8435
PLAUR 8424
RAB34 8420
RAB27A 8411
PSMD4 8402
DCTN4 8387
GCNT1 8379
TNIP1 8378
COPA 8366
RAB20 8351
MRTFA 8350
VDR 8348
DCAF6 8336
AGTPBP1 8330
RHOA 8319
RAB1B 8313
FUCA2 8304
FN1 8284
UBE2J2 8268
PSME3 8251
ST8SIA4 8236
TRIM25 8226
GALNT7 8224
RAB40C 8215
C1GALT1C1 8153
RAB6A 8148
TRIM27 8142
CAPZA1 8135
RAB3A 8133
SEC24D 8115
PSMB5 8101
ANKRD9 8085
GAS6 8063
RPN1 8024
CAPZB 8015
H2BC5 8003
NCOR2 7985
COMMD9 7967
LTBP1 7962
NANS 7957
TMED7 7950
RAB4A 7941
H2AC6 7934
JOSD2 7931
UBE2W 7929
MAN1A1 7927
NUP214 7921
RNF7 7913
H2BC11 7912
FSTL1 7908
COPB2 7902
TTLL4 7901
CALU 7894
EPAS1 7886
ARF5 7885
NUS1 7864
WSB1 7862
VDAC2 7857
PSMD6 7846
DPH3 7837
USP4 7812
TRAPPC1 7806
RAB18 7801
CNIH1 7779
UBA3 7767
PROS1 7758
MPDU1 7751
WSB2 7743
DYNC1I2 7735
ARF3 7732
KDELR2 7728
ETFB 7688
UBE2H 7663
SEC24A 7660
TOP1 7645
MBD6 7623
PSMD9 7620
ACTR10 7605
SPTA1 7595
COPG2 7594
ARSB 7572
UBE2L3 7561
H2BC18 7547
USP10 7542
YOD1 7533
ADAMTSL4 7530
HNRNPK 7522
ELOC 7519
LRRC41 7515
H2AC11 7513
COPG1 7509
FBXO7 7498
RXRA 7495
ELOB 7482
UBE2M 7477
CFP 7445
HIF1A 7436
NR1H2 7415
PSMD2 7411
FUCA1 7408
H2BC4 7389
ARSD 7365
AMFR 7363
PIAS1 7361
TADA3 7356
COMMD8 7353
UBE2F 7341
SEC23A 7335
PSMA1 7329
COPB1 7321
TUBA1A 7313
UBE2A 7309
DCTN6 7300
H2BC17 7285
RAB33B 7267
FPGT 7264
PSMD1 7241
TUBB4B 7240
SLC35A1 7225
TUBA1C 7198
MELTF 7197
PSMB3 7171
TMED9 7167
STX5 7166
TFG 7160
RPN2 7140
MAVS 7124
TRAPPC3 7114
RAB39A 7113
TAF10 7110
RAB5A 7103
MCFD2 7099
PSMA7 7096
RAB14 7095
UBA1 7089
LMAN2 7080
GALNT4 7072
IDE 7051
CPM 7044
SUMO3 7042
PIGS 7033
F8 7022
PSMC1 7021
UBE2B 7003
ACTR1A 7002
TADA2B 6952
DYNC1LI1 6941
LMAN2L 6937
DDOST 6931
RTN4RL2 6898
COPE 6896
SUMO1 6889
VCP 6886
UBE2K 6884
SEL1L 6847
CUL3 6821
PPP6C 6819
PSMB6 6813
NFKBIA 6807
RNF123 6802
SATB2 6781
WDTC1 6779
UBE2E1 6759
XRCC4 6758
ST6GALNAC2 6746
ST3GAL6 6701
FBXO11 6698
RAB5B 6690
TDG 6672
PSMF1 6659
USP22 6652
UBB 6639
PSMC6 6635
RNF40 6628
MAN2A2 6625
GORASP1 6606
PIGF 6597
COPS7A 6590
RENBP 6585
MUC1 6573
FBXW2 6560
PSMD12 6556
IGFBP7 6545
CCDC22 6533
RAB8B 6529
DCUN1D1 6523
BECN1 6516
RAD23A 6512
GALNT1 6508
RNF185 6491
NEDD8 6482
SAR1B 6479
RAB43 6433
RARA 6429
PARK7 6421
USP8 6418
FOXO4 6391
KBTBD7 6376
PREB 6368
CALR 6340
USP7 6323
COL7A1 6304
TTLL7 6266
MGAT1 6257
BRCA1 6248
RRAGA 6244
TSTA3 6241
INO80C 6240
HNRNPC 6239
PSMD11 6231
ASB7 6221
GOLGA2 6203
FBXW11 6196
RAB21 6165
STAM2 6159
USP15 6148
BRCC3 6145
COPS2 6139
EP300 6129
HDAC7 6122
ANO8 6099
HIPK2 6078
NSMCE1 6056
RAB6B 6053
TMED2 6052
RNF181 6022
ZBED1 6017
COPS3 6005
DCTN3 5994
GPAA1 5992
AREG 5977
PSMA6 5970
LAMB1 5966
PSMD7 5963
VNN3 5958
DYNLL1 5952
THBS1 5951
PSMD13 5948
CHST8 5900
DAD1 5895
PDIA6 5882
APOA2 5879
SEC22B 5873
COMMD1 5871
B3GNT2 5868
NSMCE2 5864
CD59 5859
BCL10 5849
ST3GAL4 5781
PSMD8 5757
SEC13 5748
ALG14 5746
RNF20 5727
TPST2 5725
TUBB6 5685
TAB1 5681
CETN2 5642
RAB36 5636
NTNG2 5601
ARCN1 5580
MIA2 5574
TNIP2 5552
FBXL13 5534
CANX 5528
B3GNTL1 5520
TUBA1B 5509
TMEM115 5508
COMMD5 5497
FBXL4 5496
SP3 5490
TUBB1 5488
HDAC2 5482
USP9X 5464
CBX8 5448
PIGX 5399
SDC2 5397
H2BC9 5394
IKBKG 5377
RAB24 5354
TTLL12 5353
PSMA2 5339
TRAPPC9 5333
H2BC15 5312
TFPT 5309
STAG2 5301
WAC 5267
PPP6R1 5263
TMEM132A 5245
GGCX 5237
COMMD7 5226
PRKCSH 5220
YKT6 5205
TRAPPC5 5191
PIAS4 5184
RAE1 5164
FEM1C 5160
METTL22 5157
TGFB1 5153
KLHL5 5105
UBE2C 5101
UGGT1 5082
DCTN1 5078
KDM1B 5073
KLHL21 5054
CDC73 5020
UBE2E3 5005
GCNT3 4996
SLC17A5 4989
USP12 4974
H2AC20 4972
SUMO2 4961
GMDS 4937
DCAF10 4922
UBE2G1 4921
CISH 4915
SMAD2 4905
KEAP1 4898
UGGT2 4897
ASB8 4884
FBXL20 4844
AR 4840
FBN1 4836
UBE2S 4746
DPM2 4721
IKBKE 4715
BIRC2 4692
FBXO30 4683
UBE2D2 4657
SEC16A 4619
PSMD3 4618
NRIP1 4609
PTRH2 4601
SUDS3 4526
NUP50 4521
HGS 4513
FBXL15 4499
NCOA1 4483
C4A 4466
STS 4459
UBC 4439
TPGS1 4435
FEM1B 4426
ING2 4415
RAB11B 4402
USP48 4399
KCTD6 4371
COPS5 4361
SEM1 4348
VDAC1 4347
DCUN1D3 4333
CD109 4316
SP100 4314
FCGR3B 4313
MDM2 4312
RFT1 4309
RAB19 4300
DNMT3B 4294
B4GALT1 4292
SKP1 4287
COMMD10 4274
DYNC1LI2 4273
COG7 4269
HCFC1 4254
PEX5 4225
DYNC1I1 4187
PMM1 4176
USO1 4154
TRAPPC6B 4147
NAPG 4139
PDIA3 4128
STT3A 4095
RAB9A 4088
PSMB2 4084
COPZ1 4035
SENP2 4030
FBXL8 4021
CDC20 3998
PPARGC1A 3988
RAB35 3981
SRD5A3 3971
TMEM129 3961
SSPO 3959
ADRM1 3953
RBX1 3934
RAB42 3932
TGFBR2 3914
SERPINA10 3902
GMPPA 3886
RAB8A 3880
OTOA 3867
FN3K 3813
BIRC5 3738
ZRANB1 3730
ARFGAP3 3714
VHL 3674
ALB 3668
CLSPN 3640
SEC24B 3608
PIGB 3580
MFGE8 3534
RTF1 3526
SCFD1 3525
KIN 3521
AGBL5 3518
RNF2 3513
METTL21A 3509
ARSA 3486
PAF1 3478
FBXO17 3474
UBA6 3438
PSMD5 3426
CREBBP 3423
RAB27B 3386
PSMB1 3374
KTN1 3363
FOXK2 3358
CTR9 3344
AURKA 3330
ASB13 3324
ASB1 3319
FBXL18 3309
RNF152 3269
PPP6R3 3261
TUBB3 3242
APC 3240
COMMD2 3198
SOCS5 3184
NAGK 3158
ERCC8 3154
RAB4B 3137
DDA1 3127
PEX14 3125
NUP98 3101
SENP8 3086
NUP37 3074
DDB1 3060
DERL2 3041
PIGZ 3026
MBTPS1 2966
MUL1 2961
PEX2 2946
CDC25A 2911
UBE2V2 2902
DOLPP1 2858
TOPORS 2830
CUL4B 2802
TOP2A 2778
ETFBKMT 2766
SLC35C1 2750
KBTBD6 2724
TMED3 2720
SEMA5B 2706
ALG12 2659
RNF139 2627
SAFB 2615
MAGT1 2613
USP49 2612
PSMD14 2611
PSMC2 2598
MBD5 2592
DPM3 2577
PTP4A2 2561
GCNT7 2527
CUL2 2526
PSMB4 2523
CFTR 2416
MAP3K7 2395
CSNK1D 2390
SPSB1 2374
FBXO40 2368
CTSC 2326
MLEC 2322
MYC 2304
CHM 2273
BTBD1 2263
CBX4 2222
CST3 2206
DPAGT1 2163
HSP90B1 2059
CCP110 2050
MBD1 2028
ARRB1 1998
PSMC3 1976
UCHL3 1959
LSAMP 1958
FCSK 1950
FEM1A 1947
UBE2N 1936
UBXN1 1892
ASXL2 1856
PIGN 1847
GALNT3 1805
PIGQ 1782
COPS4 1776
RAD21 1709
PRMT3 1695
CCNA2 1685
ST8SIA5 1668
ALG6 1653
COPS6 1637
MGAT2 1633
STAMBP 1611
ATXN3 1601
ASB9 1587
TGFBR1 1585
DPM1 1567
PSMD10 1559
UBXN7 1556
CDK1 1540
NEGR1 1459
NAPA 1432
THRB 1429
CCDC8 1402
OTUB1 1400
PMM2 1394
KLHL9 1353
RTN4RL1 1345
ASB3 1325
STAM 1285
SHISA5 1269
BAP1 1126
UBA52 1121
TF 1102
SEC31A 1099
NCOA2 1092
B4GALNT2 1079
RAB23 1046
RBBP5 1037
RIPK2 1025
FBXL3 1005
SYVN1 992
PIGT 952
DCUN1D5 861
USP30 856
ADAMTSL3 855
AURKB 846
CUL5 834
PPARA 813
GALNT16 790
NUP62 769
KLHL13 702
ZBTB16 689
CNIH2 654
HLA-B 649
POMT2 624
SMC1A 613
HDAC1 587
CCNA1 585
RAB44 573
PEX13 571
EIF5A 553
CAMKMT 550
YY1 537
DHPS 525
NR3C1 511
ST3GAL3 505
LAMB2 501
IL33 445
VDAC3 436
DTL 428
B4GALT4 391
VCPKMT 334
SEC16B 330
TMED10 323
DPH5 315
EEF2 306
FBXW5 265
JOSD1 227
APOE 218
GALNT15 190
USP25 173
WDR5 155
WDR61 77
PIGM 62
LEO1 39
COG4 -6
TBC1D20 -18
B3GALNT2 -28
EDEM1 -114
GOSR1 -182
TRAF6 -229
RWDD3 -238
VCPIP1 -268
COG8 -346
USP19 -456
SEC23IP -468
TNKS2 -499
PRSS21 -577
BET1 -594
PSMA4 -616
ST6GALNAC4 -629
FBXO41 -657
OTULIN -683
MANEA -699
ALG5 -708
UBE2I -764
ICMT -786
GALNT6 -806
RANBP2 -820
USP33 -821
RAB12 -856
PSMC5 -863
BABAM1 -897
PGM3 -906
USP34 -944
OTUB2 -980
GANAB -986
RAD52 -1021
WDR20 -1033
COMMD6 -1053
GALNT5 -1162
NFKB2 -1165
TTLL2 -1171
MDM4 -1230
ALG2 -1259
ALG3 -1263
FBXO15 -1269
FBXL12 -1321
MAN2A1 -1349
PIAS3 -1358
COMMD3 -1363
GAN -1414
GOSR2 -1456
PIGC -1461
BGLAP -1473
CHML -1515
RAB7B -1531
ST6GAL2 -1541
CP -1561
NR4A2 -1601
DOHH -1655
DCAF7 -1721
RELA -1803
PIGV -1810
NICN1 -1831
CDCA8 -1838
POMK -1918
SELENOS -1930
ARFGAP1 -1942
INO80B -1954
SMC3 -1975
ATXN7 -1983
PUM2 -2007
MAN1A2 -2055
CSF1 -2061
CALM1 -2081
MGAT4C -2109
KDELR3 -2117
ASB14 -2170
MSLN -2192
MUCL1 -2211
DHDDS -2236
TRIM13 -2263
TRAPPC2L -2299
FBXO6 -2300
TTLL3 -2342
ENAM -2373
MGAT3 -2391
SUZ12 -2409
KAT2B -2414
DCAF11 -2444
RABGGTA -2462
HIF3A -2519
SOCS2 -2538
CD52 -2561
SEC24C -2569
HLA-A -2573
TAF9B -2599
RAB3B -2698
SERPIND1 -2722
TOP2B -2731
TOMM20 -2743
ASB6 -2763
NAPB -2780
NFRKB -2874
MUC6 -2977
MTA1 -3005
B3GNT9 -3033
DNMT3A -3039
NUP85 -3049
MOGS -3051
MGAT5 -3072
PSMB8 -3076
NEURL2 -3097
GALNT11 -3148
TPGS2 -3167
MUC4 -3191
COG5 -3259
CUL7 -3334
GALNT10 -3341
OBSL1 -3404
BARD1 -3419
ADAMTS5 -3479
ZNF350 -3507
SPTBN5 -3531
THSD4 -3560
ALG11 -3593
NR1H3 -3597
ALG8 -3635
DOLK -3639
MARCHF6 -3678
NGLY1 -3686
FBXO22 -3709
ADAMTS17 -3827
NEU3 -3833
PROZ -3872
USP47 -3954
RAB41 -3974
DYNLL2 -3980
B3GNT3 -4017
SPSB2 -4034
TNC -4039
RING1 -4063
TULP4 -4065
BMP4 -4081
DCTN5 -4086
MUC16 -4104
POMGNT2 -4115
TTLL5 -4116
PCGF2 -4135
TTL -4136
RAB22A -4208
KBTBD8 -4224
SEC22C -4248
SMC6 -4277
MDGA1 -4285
GBF1 -4290
C1GALT1 -4297
RNF168 -4331
ADAMTS13 -4374
NR1I2 -4435
RAB26 -4448
RPS2 -4499
GPS1 -4517
RNF103 -4536
MUC5B -4613
CBX2 -4617
COMMD4 -4618
RCE1 -4674
BLM -4690
ARSG -4773
LARGE2 -4786
CUL4A -4810
DCUN1D2 -4811
MAN1B1 -4871
ACTR8 -4894
ANK3 -4919
BTRC -4924
SEC22A -5052
TRIM28 -5056
FOXK1 -5059
FBXO27 -5074
EEF1A1 -5087
SPTBN2 -5129
OTUD5 -5132
PIGP -5179
FUOM -5190
GNE -5192
BTBD6 -5202
INO80D -5234
CDKN2A -5236
RABGGTB -5240
USP14 -5246
TTLL11 -5257
TECTA -5268
PSMA3 -5285
ST6GALNAC1 -5314
FOLR2 -5337
GOLGB1 -5370
COG3 -5426
RAB15 -5520
ARSJ -5542
NUP42 -5564
DCAF13 -5572
TRAF3 -5576
ASB4 -5604
B4GAT1 -5642
MGAT4A -5680
PSMB10 -5735
ARFGAP2 -5786
COG6 -5811
SCMH1 -5839
MVD -5850
LARGE1 -5910
INCENP -5956
MUC20 -5962
PCNA -5969
PIGK -5994
SPSB3 -6020
B4GALT2 -6034
PSMA5 -6053
USP5 -6068
SEH1L -6069
PSME4 -6087
NUDT14 -6100
CUL9 -6106
FBXL14 -6145
MIA3 -6245
ANKRD28 -6250
DDX17 -6274
KLHL11 -6286
NUP153 -6321
STAG1 -6347
LYPD5 -6380
THRA -6387
RNF5 -6413
FBXO10 -6427
CTBP1 -6456
GFPT1 -6462
UBA2 -6489
RAB9B -6552
CAND1 -6554
H2BU1 -6555
PEX10 -6570
FBXW7 -6600
FGF23 -6622
FBXL16 -6648
ASB16 -6665
SENP5 -6689
TRAPPC4 -6712
ADAMTS14 -6719
TRRAP -6722
USP13 -6737
MAN1C1 -6804
ITIH2 -6820
GOLM1 -6842
RPS27A -6938
USP21 -6972
TPR -7028
ADAMTS6 -7055
SMC5 -7084
OGT -7119
POM121C -7188
PIGA -7195
THSD1 -7288
LYPD3 -7315
GMPPB -7332
FBXW9 -7360
DAG1 -7379
MYSM1 -7386
BET1L -7405
ST3GAL1 -7442
ACTL6A -7468
MXRA8 -7477
PIAS2 -7496
GPLD1 -7524
POLB -7537
NRN1L -7549
ENGASE -7552
IGFBP4 -7582
PSMA8 -7606
TTLL1 -7612
LRR1 -7643
ALG13 -7645
APOL1 -7657
DYNC1H1 -7685
GALNT9 -7716
USP44 -7754
NUP133 -7762
SPTBN1 -7764
UCHL5 -7861
GALNT8 -7869
SATB1 -7905
COG2 -7917
USP16 -7920
ST8SIA1 -7949
INO80E -7964
SENP1 -7970
PIGG -8008
SBSPON -8022
UBE2G2 -8035
ALG10 -8061
PHC3 -8152
AXIN2 -8154
ALG10B -8242
MCRS1 -8262
SKP2 -8279
SAE1 -8283
POM121 -8299
ADAMTSL5 -8317
FBXO2 -8324
RECK -8343
SMAD4 -8351
FBXW12 -8358
KLHL42 -8367
SHPRH -8381
ADAMTS16 -8387
AAAS -8389
PHC1 -8402
DPH6 -8472
NUP54 -8479
TNIP3 -8502
TTLL13P -8507
MEN1 -8538
TOMM70 -8541
THSD7A -8596
RUVBL1 -8612
POMT1 -8665
PML -8693
TRAPPC2 -8704
UBE2T -8710
RAB38 -8714
INO80 -8723
TNKS -8738
PEX12 -8753
COPS8 -8755
B4GALT6 -8785
PGAP1 -8788
ALG1 -8792
PIGO -8810
DERL1 -8963
RAB2B -8982
CNIH3 -9011
ESR1 -9122
PSMC4 -9127
TUBB4A -9162
PIGU -9200
FBXL22 -9210
AGBL2 -9212
CCNF -9262
CBX5 -9272
CYLD -9359
TRAPPC10 -9369
AGBL3 -9406
PIGH -9444
NANP -9448
IGFBP3 -9455
SEMA5A -9495
NUP43 -9517
NPM1 -9532
FBXO44 -9627
GNPNAT1 -9662
DCAF5 -9664
LMO7 -9709
GFPT2 -9713
CHD3 -9737
FUT8 -9755
ALG9 -9766
WFS1 -9774
COPS7B -9775
BMI1 -9829
DDX5 -9843
RAB30 -9844
EEF2KMT -9857
GALNT12 -9866
DCAF8 -9875
NR2C1 -9913
UHRF2 -9937
SPRN -9939
TUBA3D -9947
NOP58 -9951
PSME1 -9991
DCUN1D4 -10001
FBXW8 -10013
PROC -10098
RAB29 -10185
USP37 -10210
PRKDC -10219
B3GNT4 -10231
NUP155 -10233
HIC1 -10249
CASP8AP2 -10254
SPON1 -10262
AXIN1 -10285
ASXL1 -10309
PSME2 -10336
SMURF2 -10340
MAT2B -10365
NUP107 -10421
SIN3A -10493
NUP160 -10557
DAXX -10575
AMDHD2 -10584
POFUT2 -10597
FBXO32 -10607
NUP35 -10611
STAMBPL1 -10617
NR3C2 -10625
LMAN1 -10630
HERC2 -10658
KLHL25 -10671
MUC12 -10704
NUP210 -10726
DNAJC24 -10746
B4GALT3 -10759
MPI -10760
OTUD3 -10763
HLTF -10765
RCN1 -10766
L3MBTL2 -10770
KAT2A -10771
DPH7 -10779
FBXO21 -10790
ADAMTS4 -10829
COPZ2 -10863
TP53 -10893
UBE2Z -10912
TRAPPC6A -10917
HSPA8 -10922
NAE1 -10931
RAB33A -10940
TNFAIP3 -10950
TP53BP1 -10992
GCNT4 -10997
DPH2 -11005
STX17 -11006
LYPD2 -11013
ADAMTS10 -11036
OTUD7A -11041
RIPK1 -11074
BIRC3 -11125
RNF144A -11164
ARSK -11166
NSMCE4A -11187
ACTR5 -11217
FN3KRP -11220
ZNF131 -11283
USP24 -11306
DCAF4 -11310
NUP205 -11321
PSMB9 -11324
CUL1 -11330
IFIH1 -11332
DPH1 -11342
DCAF17 -11365
USP42 -11367
RAB40B -11375
NUP88 -11397
H2AW -11403
KLHL22 -11407
SPTAN1 -11426
ADAMTS1 -11438
XPC -11450
KLHL20 -11483
USP20 -11488
ST8SIA6 -11516
RAB39B -11529
DDB2 -11530
KCTD7 -11546
UBE2Q2 -11554
WDR48 -11565
ST3GAL5 -11568
NUP93 -11620
NUP188 -11624
KLHL3 -11635
PIGL -11711
DCAF16 -11717
RANGAP1 -11722
PIGW -11723
EIF5A2 -11741
SMAD3 -11745
TRAF2 -11746
NSMCE3 -11748
FBXW4 -11757
B3GLCT -11758
PARP1 -11764
RAB37 -11793
CHST10 -11841
FBXO4 -11843
EID3 -11870
SMAD7 -11872
ADRB2 -11892
RAD18 -11916
POMGNT1 -11937
DDX58 -11950
FBXO31 -11953
ASB2 -11978
RORA -11979
NUB1 -11986
RPA1 -12004
SUMF2 -12038
WRN -12047
ST6GAL1 -12052
MDC1 -12059
ST6GALNAC6 -12085
OTUD7B -12095
COG1 -12125
XPNPEP2 -12151
RBBP7 -12155
UAP1 -12166
NDC1 -12173
GATA3 -12191
USP18 -12214
DNMT1 -12257
C3 -12262
NOD1 -12263
LY6E -12264
SPON2 -12276
PRSS23 -12288
B3GNT7 -12298
USP28 -12317
USP11 -12333


Response to elevated platelet cytosolic Ca2+

Response to elevated platelet cytosolic Ca2+
1010
set Response to elevated platelet cytosolic Ca2+
setSize 110
pANOVA 1.25e-16
s.dist 0.457
p.adjustANOVA 1.22e-14



Top enriched genes

Top 20 genes
GeneID Gene Rank
F5 9485
CYB5R1 9460
CD36 9444
CLU 9371
APLP2 9347
QSOX1 9298
CD63 9287
ALDOA 9249
LHFPL2 9224
FERMT3 9223
APP 9177
SERPINA1 9168
ACTN1 9094
STXBP2 9035
ITGA2B 8893
F13A1 8876
HGF 8863
TOR4A 8861
VTI1B 8850
LAMP2 8786

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
F5 9485
CYB5R1 9460
CD36 9444
CLU 9371
APLP2 9347
QSOX1 9298
CD63 9287
ALDOA 9249
LHFPL2 9224
FERMT3 9223
APP 9177
SERPINA1 9168
ACTN1 9094
STXBP2 9035
ITGA2B 8893
F13A1 8876
HGF 8863
TOR4A 8861
VTI1B 8850
LAMP2 8786
SRGN 8761
TIMP1 8677
TLN1 8525
CLEC3B 8480
SELP 8457
ITGB3 8291
FN1 8284
SYTL4 8256
ANXA5 8210
CFL1 8186
EGF 8179
CAP1 8111
GAS6 8063
LY6G6F 8023
ORM1 7971
CALU 7894
PECAM1 7855
SCCPDH 7787
PROS1 7758
MMRN1 7714
SERPINE1 7483
VEGFA 7467
ABCC4 7434
STXBP3 7424
TAGLN2 7367
SPARC 7339
VCL 7328
PSAP 7145
PRKCB 7097
HSPA5 7029
F8 7022
WDR1 6976
VEGFC 6906
VWF 6641
TUBA4A 6484
GTPBP2 6331
TMSB4X 6295
PPBP 6042
THBS1 5951
CD9 5940
PF4 5707
A1BG 5559
PFN1 5459
PHACTR2 5410
PDGFA 5293
ECM1 5176
TGFB1 5153
ACTN4 5049
OLA1 4914
CD109 4316
ALB 3668
RAB27B 3386
ENDOD1 3361
TIMP3 3296
CHID1 2811
MANF 2550
PLEK 1999
CFD 1984
APOOL 1609
TTN 1195
PRKCA 1132
TF 1102
STX4 606
FLNA 483
TMX3 -775
PLG -1977
PCYOX1L -2009
CALM1 -2081
ORM2 -2564
MAGED2 -2687
ITIH3 -3017
SOD1 -4862
ITIH4 -6208
SERPINF2 -6574
BRPF3 -6615
PPIA -6766
TGFB2 -7492
SELENOP -7771
NHLRC2 -7835
TGFB3 -7891
VEGFB -7929
TEX264 -8366
CDC37L1 -8470
PDGFB -8577
A2M -9870
FAM3C -10062
HABP4 -10921
CTSW -11117
SERPING1 -11197
LGALS3BP -11459


Platelet degranulation

Platelet degranulation
831
set Platelet degranulation
setSize 106
pANOVA 5.81e-16
s.dist 0.455
p.adjustANOVA 5.29e-14



Top enriched genes

Top 20 genes
GeneID Gene Rank
F5 9485
CYB5R1 9460
CD36 9444
CLU 9371
APLP2 9347
QSOX1 9298
CD63 9287
ALDOA 9249
LHFPL2 9224
FERMT3 9223
APP 9177
SERPINA1 9168
ACTN1 9094
STXBP2 9035
ITGA2B 8893
F13A1 8876
HGF 8863
TOR4A 8861
VTI1B 8850
LAMP2 8786

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
F5 9485
CYB5R1 9460
CD36 9444
CLU 9371
APLP2 9347
QSOX1 9298
CD63 9287
ALDOA 9249
LHFPL2 9224
FERMT3 9223
APP 9177
SERPINA1 9168
ACTN1 9094
STXBP2 9035
ITGA2B 8893
F13A1 8876
HGF 8863
TOR4A 8861
VTI1B 8850
LAMP2 8786
SRGN 8761
TIMP1 8677
TLN1 8525
CLEC3B 8480
SELP 8457
ITGB3 8291
FN1 8284
SYTL4 8256
ANXA5 8210
CFL1 8186
EGF 8179
CAP1 8111
GAS6 8063
LY6G6F 8023
ORM1 7971
CALU 7894
PECAM1 7855
SCCPDH 7787
PROS1 7758
MMRN1 7714
SERPINE1 7483
VEGFA 7467
ABCC4 7434
TAGLN2 7367
SPARC 7339
VCL 7328
PSAP 7145
HSPA5 7029
F8 7022
WDR1 6976
VEGFC 6906
VWF 6641
TUBA4A 6484
GTPBP2 6331
TMSB4X 6295
PPBP 6042
THBS1 5951
CD9 5940
PF4 5707
A1BG 5559
PFN1 5459
PHACTR2 5410
PDGFA 5293
ECM1 5176
TGFB1 5153
ACTN4 5049
OLA1 4914
CD109 4316
ALB 3668
RAB27B 3386
ENDOD1 3361
TIMP3 3296
CHID1 2811
MANF 2550
PLEK 1999
CFD 1984
APOOL 1609
TTN 1195
TF 1102
FLNA 483
TMX3 -775
PLG -1977
PCYOX1L -2009
CALM1 -2081
ORM2 -2564
MAGED2 -2687
ITIH3 -3017
SOD1 -4862
ITIH4 -6208
SERPINF2 -6574
BRPF3 -6615
PPIA -6766
TGFB2 -7492
SELENOP -7771
NHLRC2 -7835
TGFB3 -7891
VEGFB -7929
TEX264 -8366
CDC37L1 -8470
PDGFB -8577
A2M -9870
FAM3C -10062
HABP4 -10921
CTSW -11117
SERPING1 -11197
LGALS3BP -11459


Toll-like Receptor Cascades

Toll-like Receptor Cascades
1245
set Toll-like Receptor Cascades
setSize 143
pANOVA 2.29e-15
s.dist 0.384
p.adjustANOVA 1.96e-13



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A9 9516
S100A12 9515
S100A8 9503
CD36 9444
ITGAM 9398
CTSB 9364
NKIRAS2 9353
TLR8 9343
DUSP3 9280
TLR5 9201
UBE2D1 9187
APP 9177
IRAK3 9107
MAPK14 9104
TLR2 9103
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
ITGB2 8942

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A9 9516
S100A12 9515
S100A8 9503
CD36 9444
ITGAM 9398
CTSB 9364
NKIRAS2 9353
TLR8 9343
DUSP3 9280
TLR5 9201
UBE2D1 9187
APP 9177
IRAK3 9107
MAPK14 9104
TLR2 9103
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
ITGB2 8942
TLR1 8932
MAP2K6 8887
TLR6 8840
LY96 8795
MAP2K3 8748
UBE2D3 8640
NOD2 8442
MAPKAPK3 8382
CTSS 8372
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966
CNPY3 7761
PELI3 7716
PPP2CB 7712
RPS6KA1 7695
LY86 7667
TANK 7502
MAPK1 7493
BTK 7206
DNM3 7045
TAB2 6964
MAP2K4 6866
NFKBIA 6807
PELI1 6715
BPI 6666
UBB 6639
TICAM2 6335
TICAM1 6307
NFKB1 6277
FBXW11 6196
MAP3K8 6160
IRAK1 6131
DNM2 6089
ATF1 5706
TAB1 5681
FADD 5641
TIRAP 5640
UBE2V1 5637
TNIP2 5552
FOS 5460
IKBKG 5377
PTPN11 5314
MAP3K1 5121
CTSK 5059
PLCG2 5006
ECSIT 4918
IKBKE 4715
BIRC2 4692
UBE2D2 4657
EEA1 4641
PPP2R1A 4589
UBC 4439
DUSP6 4357
MAPK10 4325
SKP1 4287
CTSL 4231
RIPK3 4217
UNC93B1 4170
MAPKAPK2 4054
SOCS1 3947
MAPK11 3826
JUN 3722
DNM1 3587
TBK1 3229
TAB3 3160
RPS6KA2 3087
RPS6KA3 2973
PPP2R5D 2421
MAP3K7 2395
ATF2 2085
HSP90B1 2059
UBE2N 1936
MAP2K7 1654
PIK3C3 1619
AGER 1294
VRK3 1281
UBA52 1121
ELK1 1040
RIPK2 1025
NKIRAS1 375
NFKBIB -152
TRAF6 -229
PPP2R1B -241
HMGB1 -252
MEF2C -293
CD180 -600
TLR7 -625
NFKB2 -1165
MAPK7 -1337
CREB1 -1378
RELA -1803
TLR10 -2961
CTSV -3036
DUSP7 -3211
PIK3R4 -4062
RBSN -4542
LGMN -4644
BTRC -4924
IKBKB -5386
S100B -5457
TRAF3 -5576
TLR9 -5999
DUSP4 -6287
RPS27A -6938
MAPK9 -7068
S100A1 -8108
IRF3 -8517
IRF7 -8657
MAPK8 -9428
IRAK2 -9548
SIGIRR -10752
RIPK1 -11074
BIRC3 -11125
CUL1 -11330
CASP8 -11336
TLR3 -11525
RPS6KA5 -11594
SARM1 -12134
PTPN4 -12220
NOD1 -12263


Asparagine N-linked glycosylation

Asparagine N-linked glycosylation
86
set Asparagine N-linked glycosylation
setSize 269
pANOVA 5.32e-15
s.dist 0.277
p.adjustANOVA 4.27e-13



Top enriched genes

Top 20 genes
GeneID Gene Rank
CTSA 9514
NPL 9498
ASGR2 9487
F5 9485
ASGR1 9212
ARF4 9191
SERPINA1 9168
DCTN2 9157
SPTB 9154
CD55 9145
KDELR1 9142
ST6GALNAC3 9134
ARF1 9064
RAB1A 9052
NEU1 9029
CTSZ 8975
OS9 8898
TGFA 8889
RAD23B 8886
CMAS 8839

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CTSA 9514
NPL 9498
ASGR2 9487
F5 9485
ASGR1 9212
ARF4 9191
SERPINA1 9168
DCTN2 9157
SPTB 9154
CD55 9145
KDELR1 9142
ST6GALNAC3 9134
ARF1 9064
RAB1A 9052
NEU1 9029
CTSZ 8975
OS9 8898
TGFA 8889
RAD23B 8886
CMAS 8839
B4GALT5 8830
NSF 8829
ANK1 8771
GLB1 8725
EDEM2 8704
MGAT4B 8675
ST3GAL2 8669
CAPZA2 8597
EDEM3 8538
DCTN4 8387
COPA 8366
RAB1B 8313
ST8SIA4 8236
CAPZA1 8135
SEC24D 8115
RPN1 8024
CAPZB 8015
NANS 7957
TMED7 7950
MAN1A1 7927
COPB2 7902
ARF5 7885
NUS1 7864
TRAPPC1 7806
CNIH1 7779
MPDU1 7751
DYNC1I2 7735
ARF3 7732
KDELR2 7728
SEC24A 7660
ACTR10 7605
SPTA1 7595
COPG2 7594
COPG1 7509
FUCA1 7408
AMFR 7363
SEC23A 7335
COPB1 7321
DCTN6 7300
FPGT 7264
SLC35A1 7225
TMED9 7167
STX5 7166
TFG 7160
RPN2 7140
TRAPPC3 7114
MCFD2 7099
LMAN2 7080
F8 7022
PSMC1 7021
ACTR1A 7002
DYNC1LI1 6941
LMAN2L 6937
DDOST 6931
COPE 6896
VCP 6886
SEL1L 6847
PPP6C 6819
ST6GALNAC2 6746
ST3GAL6 6701
UBB 6639
MAN2A2 6625
GORASP1 6606
RENBP 6585
RNF185 6491
SAR1B 6479
PREB 6368
CALR 6340
COL7A1 6304
MGAT1 6257
TSTA3 6241
GOLGA2 6203
TMED2 6052
DCTN3 5994
AREG 5977
DYNLL1 5952
CHST8 5900
DAD1 5895
SEC22B 5873
CD59 5859
ST3GAL4 5781
SEC13 5748
ALG14 5746
ARCN1 5580
MIA2 5574
CANX 5528
TMEM115 5508
TRAPPC9 5333
PPP6R1 5263
PRKCSH 5220
YKT6 5205
TRAPPC5 5191
UGGT1 5082
DCTN1 5078
SLC17A5 4989
GMDS 4937
UGGT2 4897
DPM2 4721
SEC16A 4619
UBC 4439
RFT1 4309
B4GALT1 4292
DYNC1LI2 4273
COG7 4269
DYNC1I1 4187
PMM1 4176
USO1 4154
TRAPPC6B 4147
NAPG 4139
PDIA3 4128
STT3A 4095
COPZ1 4035
SRD5A3 3971
GMPPA 3886
ARFGAP3 3714
SEC24B 3608
SCFD1 3525
PPP6R3 3261
NAGK 3158
DERL2 3041
DOLPP1 2858
SLC35C1 2750
TMED3 2720
ALG12 2659
RNF139 2627
MAGT1 2613
DPM3 2577
CSNK1D 2390
CTSC 2326
MLEC 2322
DPAGT1 2163
FCSK 1950
UBXN1 1892
ST8SIA5 1668
ALG6 1653
MGAT2 1633
DPM1 1567
NAPA 1432
PMM2 1394
UBA52 1121
SEC31A 1099
B4GALNT2 1079
SYVN1 992
CNIH2 654
ST3GAL3 505
B4GALT4 391
SEC16B 330
TMED10 323
COG4 -6
TBC1D20 -18
EDEM1 -114
GOSR1 -182
COG8 -346
SEC23IP -468
BET1 -594
ST6GALNAC4 -629
MANEA -699
ALG5 -708
PGM3 -906
GANAB -986
ALG2 -1259
ALG3 -1263
MAN2A1 -1349
GOSR2 -1456
ST6GAL2 -1541
ARFGAP1 -1942
MAN1A2 -2055
MGAT4C -2109
KDELR3 -2117
DHDDS -2236
TRIM13 -2263
TRAPPC2L -2299
MGAT3 -2391
SEC24C -2569
NAPB -2780
MOGS -3051
MGAT5 -3072
COG5 -3259
SPTBN5 -3531
ALG11 -3593
ALG8 -3635
DOLK -3639
MARCHF6 -3678
NGLY1 -3686
NEU3 -3833
DYNLL2 -3980
DCTN5 -4086
SEC22C -4248
GBF1 -4290
RNF103 -4536
MAN1B1 -4871
ANK3 -4919
SEC22A -5052
SPTBN2 -5129
FUOM -5190
GNE -5192
ST6GALNAC1 -5314
GOLGB1 -5370
COG3 -5426
MGAT4A -5680
ARFGAP2 -5786
COG6 -5811
MVD -5850
B4GALT2 -6034
NUDT14 -6100
MIA3 -6245
ANKRD28 -6250
RNF5 -6413
GFPT1 -6462
TRAPPC4 -6712
MAN1C1 -6804
RPS27A -6938
GMPPB -7332
BET1L -7405
ST3GAL1 -7442
ENGASE -7552
ALG13 -7645
DYNC1H1 -7685
SPTBN1 -7764
COG2 -7917
ST8SIA1 -7949
ALG10 -8061
ALG10B -8242
TRAPPC2 -8704
B4GALT6 -8785
ALG1 -8792
DERL1 -8963
CNIH3 -9011
TRAPPC10 -9369
NANP -9448
GNPNAT1 -9662
GFPT2 -9713
FUT8 -9755
ALG9 -9766
AMDHD2 -10584
LMAN1 -10630
B4GALT3 -10759
MPI -10760
COPZ2 -10863
TRAPPC6A -10917
STX17 -11006
SPTAN1 -11426
ST8SIA6 -11516
ST3GAL5 -11568
CHST10 -11841
ST6GAL1 -12052
ST6GALNAC6 -12085
COG1 -12125
UAP1 -12166


Metabolism of lipids

Metabolism of lipids
643
set Metabolism of lipids
setSize 625
pANOVA 9.17e-15
s.dist 0.181
p.adjustANOVA 6.95e-13



Top enriched genes

Top 20 genes
GeneID Gene Rank
PPARG 9522
PLBD1 9521
CTSA 9514
CYP1B1 9502
CYP19A1 9497
PLB1 9490
HADHB 9450
CD36 9444
HSD3B7 9441
PLIN3 9437
PRKACA 9429
GGT1 9426
PCTP 9376
ACOX2 9373
TSPO 9351
TNFAIP8L3 9316
GPX1 9314
PLD1 9306
LTA4H 9261
AGPAT2 9256

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PPARG 9522
PLBD1 9521
CTSA 9514
CYP1B1 9502
CYP19A1 9497
PLB1 9490
HADHB 9450
CD36 9444
HSD3B7 9441
PLIN3 9437
PRKACA 9429
GGT1 9426
PCTP 9376
ACOX2 9373
TSPO 9351
TNFAIP8L3 9316
GPX1 9314
PLD1 9306
LTA4H 9261
AGPAT2 9256
ACSL1 9217
SGMS2 9213
OLAH 9184
PLA2G4A 9180
ACER3 9165
DGAT2 9158
PTGR1 9126
CRLS1 9116
FIG4 9115
CERS2 9108
SBF2 9078
MTMR3 9069
ARF1 9064
GM2A 9059
PIK3CB 9038
VAPA 9033
NEU1 9029
INPPL1 9028
CARM1 9020
ALOX5 9001
SUMF1 8991
GK 8973
GBA 8969
PPT1 8950
PNPLA2 8939
MTF1 8925
CRAT 8920
PISD 8908
ME1 8892
TBXAS1 8862
ACOX1 8859
HSD17B4 8858
CHPT1 8846
FAR2 8808
ACSL4 8802
SGMS1 8782
HEXB 8776
FAR1 8754
PLA2G15 8747
PECR 8739
GLB1 8725
ELOVL3 8710
HADHA 8694
SMARCD3 8668
BMX 8664
ALDH3B1 8663
PGS1 8654
GDE1 8642
LPCAT3 8609
LPCAT2 8606
SPTLC1 8588
LPGAT1 8574
GLA 8570
SPTLC2 8547
ACSS3 8546
MBOAT7 8536
ASAH1 8529
GPCPD1 8527
SLC44A1 8526
GLTP 8477
PTGS1 8467
PTEN 8460
GALC 8443
ALOX15B 8427
MBOAT2 8362
VDR 8348
SLC27A1 8305
ACAA1 8292
ACADVL 8290
PLIN2 8261
SP1 8193
TXNRD1 8192
GPAT3 8177
AGPAT1 8158
SEC24D 8115
LBR 8102
HMGCR 8094
ARNT 8047
MTMR14 8032
ACOT8 8018
HSD17B11 8008
NCOR2 7985
MTMR10 7964
PLPP3 7955
SRD5A1 7951
RAB4A 7941
ABHD5 7915
CERT1 7889
TBL1X 7887
ALOX5AP 7881
MTMR6 7878
PCYT1B 7858
ACSL3 7840
ALAS1 7804
GLIPR1 7739
ARF3 7732
PNPLA8 7709
ELOVL7 7706
FADS1 7699
MGLL 7694
SEC24A 7660
SPHK1 7657
NFYC 7653
RGL1 7647
DHRS7B 7629
CDK19 7618
SAMD8 7614
ARSB 7572
ALOX12 7559
GPD2 7555
MED8 7535
RXRA 7495
AHR 7479
HPGD 7416
NR1H2 7415
STARD3NL 7374
FDFT1 7372
ARSD 7365
PLD3 7364
ABCD1 7346
SEC23A 7335
G0S2 7272
PIK3R6 7270
IDI1 7247
HSD17B12 7181
PLD2 7180
PSAP 7145
RAB5A 7103
RAB14 7095
ELOVL1 7088
PPP1CB 7064
OSBPL8 6960
ABHD3 6943
SLC22A5 6929
HACD4 6870
PNPLA6 6863
CYP51A1 6844
PCYT1A 6816
PTDSS1 6778
GNPAT 6753
MED20 6743
SREBF2 6695
DHCR7 6676
CDS2 6557
SREBF1 6539
CPT2 6538
NUDT19 6494
SAR1B 6479
PIP5K1B 6450
OCRL 6442
INSIG2 6430
ABHD4 6425
OSBPL9 6404
RUFY1 6399
CSNK2A2 6388
PPP1CC 6330
SYNJ1 6296
CYP4F3 6259
UGCG 6247
DBI 6227
CDIPT 6222
MED25 6209
CSNK2A1 6199
MTM1 6198
DEGS1 6169
EHHADH 6140
EP300 6129
PIP5K1A 6110
ABCA1 6109
MED13L 6077
CHKA 6073
PIK3CD 6046
GDPD3 6027
FABP5 6021
ELOVL5 6011
ACOX3 5995
ORMDL2 5967
ESRRA 5943
NCOR1 5887
APOA2 5879
CPNE3 5872
PTDSS2 5867
CERS6 5795
PITPNM1 5791
NCOA6 5773
NDUFAB1 5759
ABCC3 5717
PLA2G12A 5705
PLAAT1 5692
TNFAIP8L2 5671
B3GALNT1 5619
ACAT1 5542
MBOAT1 5500
AGPS 5495
MCAT 5450
ACOT9 5446
ACOT13 5423
HMGCL 5349
FDPS 5335
ACACA 5315
DECR1 5313
DGAT1 5306
MED16 5278
PIAS4 5184
ACLY 5159
GPX4 5150
OSBPL2 5117
PTGES 5102
CPT1A 5077
CYP2C9 5042
PIK3R2 5010
SUMO2 4961
SLC25A1 4955
ACAD10 4823
AGPAT3 4809
STARD10 4808
FDXR 4766
PTGS2 4753
ACOXL 4749
HSD17B13 4718
HDAC3 4673
SPTSSA 4652
PIK3CA 4629
NSDHL 4594
TBL1XR1 4556
HACD1 4548
FHL2 4524
NCOA1 4483
STS 4459
SCP2 4454
OSBPL6 4419
MED18 4396
MED26 4395
ACADS 4297
SQLE 4211
GPAT4 4177
PTGES3 4125
HSD17B2 4085
PPP1CA 4069
MAPKAPK2 4054
SCD 4026
PPARGC1A 3988
SRD5A3 3971
CSNK2B 3969
SLC25A20 3958
CYP27A1 3877
HSD11B2 3838
ACSM6 3832
PLA2R1 3812
FABP2 3805
MED22 3802
MMUT 3791
MID1IP1 3706
ALB 3668
HSD17B1 3654
CPTP 3651
SEC24B 3608
LIPH 3546
AKR1B15 3541
NCOA3 3522
NFYA 3506
ARSA 3486
CREBBP 3423
ACAA2 3421
PIP5K1C 3419
STARD7 3407
STARD3 3342
SGPL1 3332
PMVK 3317
ACBD7 3315
MED19 3243
MED4 3215
PIKFYVE 3187
TMEM86B 3138
PEMT 3103
MED17 3084
GLB1L 2992
GBA2 2974
MBTPS1 2966
MTMR4 2951
PHOSPHO1 2944
POMC 2855
SPHK2 2827
TAZ 2754
SLC44A2 2700
DHCR24 2694
MSMO1 2557
MED13 2533
SMPD2 2476
KPNB1 2430
PTPMT1 2213
VAPB 2194
PLPP2 2186
ACER2 2074
CBR1 2037
MED12 2034
PRKAG2 2015
CAV1 1969
CCNC 1877
SPTLC3 1857
FDX1 1854
PIK3CG 1833
PIK3C2G 1737
PIK3C3 1619
FADS2 1486
MED31 1462
MTMR9 1453
LRP2 1307
TECRL 1306
HEXA 1261
PTGR2 1238
HTD2 1183
GSTM4 1181
SMPD1 1129
CEPT1 1127
PRKD3 1104
NCOA2 1092
NUDT7 1086
PLA2G4D 1068
CSNK1G2 887
PLEKHA4 838
ALDH3A2 833
PPARA 813
DECR2 783
NPAS2 712
ABCC1 576
ECI1 486
AKR1C1 473
THRAP3 388
AACS 351
MED7 224
MBTPS2 83
CYP1A2 38
FAM120B -8
ENPP6 -56
VAC14 -124
LCLAT1 -177
MED14 -203
ACSF3 -347
LTC4S -353
TNFAIP8 -460
GRHL1 -492
PLAAT2 -544
MED11 -560
CYP46A1 -580
FASN -690
GGT5 -695
ACADL -726
UBE2I -764
SLC27A3 -798
ACOT11 -823
MED6 -842
GPS2 -889
CYP4F8 -925
GGPS1 -1066
ACSBG1 -1236
CBR4 -1239
STAR -1244
ACBD5 -1284
ACADM -1308
PLEKHA2 -1351
ETNK1 -1401
MED28 -1429
MOGAT3 -1460
HILPDA -1566
MTMR12 -1677
HACD2 -1711
PLEKHA6 -1745
SLC10A1 -1762
CDK8 -1971
HMGCS1 -1972
INPP5K -2034
MTMR2 -2216
ECHS1 -2265
PIK3R5 -2304
MFSD2A -2309
OXCT2 -2322
PIP4K2A -2365
CERS5 -2540
SEC24C -2569
PI4KA -2601
OSBP -2645
DPEP2 -2705
ARV1 -2720
CERS3 -2840
PLA2G4C -2845
DPEP3 -2894
STARD5 -2943
PLEKHA8 -3080
PHYH -3231
RXRB -3276
ACOT7 -3289
CHKB -3319
PNPLA4 -3322
MTMR1 -3383
CDS1 -3388
CPNE1 -3397
PITPNM3 -3420
PPM1L -3445
ANGPTL4 -3469
SLC44A5 -3527
GPX2 -3533
MTMR7 -3565
OSBPL10 -3580
NR1H3 -3597
SLC27A5 -3614
PLA2G10 -3617
SC5D -3695
ACAT2 -3713
PLIN1 -3785
ACP6 -3790
CYP27B1 -3807
CYP24A1 -3820
SLC27A2 -3831
NEU3 -3833
PLD6 -3870
FA2H -3949
MED1 -4036
INPP5D -4038
PIK3R4 -4062
STARD4 -4084
KDSR -4187
SCAP -4189
SIN3B -4205
CYP7B1 -4294
PI4KB -4465
ACBD4 -4503
GDPD1 -4554
CPT1B -4584
CHD9 -4585
ACOT1 -4622
LGMN -4644
MCEE -4724
ARSG -4773
PITPNM2 -4822
INPP5F -4865
FAAH2 -4912
PLEKHA5 -4963
GPAT2 -4997
FDX2 -5019
PPARGC1B -5047
PLEKHA3 -5068
FAAH -5096
PIK3C2A -5194
UGT8 -5219
CERK -5241
CERS4 -5342
ABCB4 -5440
TGS1 -5441
MED30 -5484
LPIN3 -5536
ARSJ -5542
HSD17B3 -5592
PLPP1 -5711
AHRR -5763
PLA2G2D -5777
OSBPL1A -5816
TRIB3 -5843
MVD -5850
PRXL2B -5905
ACSL6 -5913
MED21 -5937
MIGA2 -5952
ORMDL1 -5954
FITM2 -6050
PON2 -6147
FITM1 -6244
AKR1C2 -6258
PPARD -6394
PI4K2A -6666
PLA2G4B -6679
PLAAT3 -6706
ELOVL4 -6768
MED23 -6787
RAN -6791
ARNTL -6811
PNPLA7 -6877
GPD1 -6895
PTGES2 -6926
LPIN2 -6935
AMACR -6980
PITPNB -7049
CPNE7 -7075
CYP2J2 -7268
MIGA1 -7300
MECR -7348
ALOX12B -7374
MED24 -7387
ACSM3 -7398
LPCAT1 -7428
CLOCK -7460
TM7SF2 -7470
CUBN -7513
SCD5 -7756
PIP4K2B -7788
ACER1 -7850
PCCB -7976
MED29 -7985
PRKAB2 -8172
NRF1 -8183
THEM5 -8249
CYP2D6 -8301
MVK -8305
INPP5E -8363
LPCAT4 -8430
SYNJ2 -8511
AGPAT4 -8576
MED10 -8579
PCCA -8664
MED9 -8812
PEX11A -8816
SPTSSB -8818
PRKD2 -8834
INPP4B -8893
NR1D1 -8980
HELZ2 -9045
HSD17B7 -9066
ETNK2 -9115
MED27 -9191
ASAH2 -9218
SACM1L -9235
LIPE -9245
SGPP2 -9332
CYP2E1 -9363
TECR -9426
PIK3R1 -9505
MLYCD -9599
INPP4A -9634
MORC2 -9637
MED15 -9778
CYP2R1 -9918
AGPAT5 -9925
TNFAIP8L1 -9931
ACACB -9957
PTPN13 -9962
NFYB -9964
ORMDL3 -9997
MTMR8 -10026
ACOT2 -10127
EPHX2 -10186
ACAD11 -10194
FABP3 -10221
GPAM -10241
PLPP6 -10392
BDH1 -10419
GPD1L -10479
SIN3A -10493
ACSL5 -10518
SBF1 -10530
SLC25A17 -10559
LSS -10583
INSIG1 -10636
ALOX15 -10676
HSD17B8 -10724
ACOT4 -10733
GDPD5 -10745
SELENOI -10809
HACD3 -10864
PTGDS -10886
TIAM2 -10979
DEGS2 -11048
THEM4 -11069
ACBD6 -11092
ARSK -11166
ACSF2 -11266
PIK3C2B -11281
PPT2 -11340
PCYT2 -11345
PIP4K2C -11371
HADH -11421
LPIN1 -11437
ELOVL6 -11474
MMAA -11476
BDH2 -11480
TSPOAP1 -11608
DDHD1 -11616
ESYT2 -11660
OXCT1 -11698
OSBPL7 -11742
SMPD4 -11747
HACL1 -11751
ECI2 -11768
DDHD2 -11818
AKR1B1 -11917
PRKACB -11959
OSBPL3 -11960
CROT -11973
RORA -11979
PI4K2B -11980
CYP2U1 -12000
PIK3R3 -12015
EBP -12029
SUMF2 -12038
AKR1C3 -12104
AGK -12120
PLA2G6 -12122
PLEKHA1 -12149
OSBPL5 -12194
SGPP1 -12210
PLAAT4 -12230
SMPD3 -12234
ESYT1 -12237
TNFRSF21 -12254
CYP4F22 -12271
PLD4 -12365


Disease

Disease
284
set Disease
setSize 1303
pANOVA 1.32e-14
s.dist 0.127
p.adjustANOVA 9.5e-13



Top enriched genes

Top 20 genes
GeneID Gene Rank
CSF2RA 9526
ADAMTS2 9525
WASF1 9520
CTSA 9514
FZD5 9513
IDH1 9507
VCAN 9505
CYP1B1 9502
CYP19A1 9497
F12 9492
HRH2 9466
CD163 9462
TALDO1 9456
CD36 9444
PRKACA 9429
GGT1 9426
SLC1A3 9389
ADM 9378
GNS 9360
GNG10 9349

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CSF2RA 9526.0
ADAMTS2 9525.0
WASF1 9520.0
CTSA 9514.0
FZD5 9513.0
IDH1 9507.0
VCAN 9505.0
CYP1B1 9502.0
CYP19A1 9497.0
F12 9492.0
HRH2 9466.0
CD163 9462.0
TALDO1 9456.0
CD36 9444.0
PRKACA 9429.0
GGT1 9426.0
SLC1A3 9389.0
ADM 9378.0
GNS 9360.0
GNG10 9349.0
MAOA 9346.0
LMNB1 9345.0
GPR27 9340.0
OPLAH 9330.0
FCGR1A 9323.0
GRB2 9304.0
IMPDH1 9294.0
AP1S1 9286.0
H2BC21 9283.0
IL10 9272.0
CYFIP1 9265.0
PC 9263.0
ARPC1B 9259.0
TPST1 9251.0
TLR5 9201.0
UBE2D1 9187.0
NCSTN 9186.0
APP 9177.0
BSG 9172.0
KREMEN1 9149.0
SLC4A1 9141.0
ST6GALNAC3 9134.0
GPR84 9133.0
GUCY2C 9122.0
MAPK14 9104.0
TLR2 9103.0
CD14 9097.0
SYK 9076.0
FURIN 9075.0
HK1 9071.0
ARF1 9064.0
MAP2K1 9063.0
FKBP1A 9056.0
H2BC12 9051.0
YWHAE 9045.0
PIK3CB 9038.0
NEU1 9029.0
TLR4 9016.0
GYG1 9013.0
ACTB 9011.0
PAPSS1 9003.0
CLTC 9000.0
QKI 8996.0
CUX1 8986.0
ADCY3 8984.0
HCK 8976.0
ANAPC15 8968.0
KL 8963.0
HDAC4 8960.0
MAML3 8957.0
AGTRAP 8956.0
MAPK3 8953.0
TLR1 8932.0
ERLIN2 8928.0
MYO10 8918.0
IL1R1 8917.0
CRK 8906.0
NLRP3 8901.0
OS9 8898.0
ARPC1A 8894.0
ITGA2B 8893.0
ENO1 8890.0
TGFA 8889.0
MAP2K6 8887.0
ERLIN1 8869.0
CHMP4B 8866.0
HGF 8863.0
TBXAS1 8862.0
FCGR2A 8845.0
GALK1 8842.0
TLR6 8840.0
NUP58 8820.0
CEBPD 8816.0
GNG5 8815.0
LY96 8795.0
RAC1 8793.0
ADAM10 8791.0
ADAMTS3 8785.0
CHMP2A 8780.0
HEXB 8776.0
RBPJ 8770.0
MAP2K3 8748.0
APBB1IP 8744.0
JAG1 8743.0
RAB7A 8742.0
AP1B1 8730.0
GLB1 8725.0
TCN2 8721.0
GCKR 8713.0
RB1 8707.0
UBAP1 8701.0
MARK3 8697.0
ARPC5 8686.0
FOXO3 8682.0
PGK1 8672.0
ST3GAL2 8669.0
PYCARD 8638.0
AP2M1 8627.0
CDK5 8616.0
PRKAR1A 8607.0
MEFV 8605.0
E2F2 8601.0
IRS2 8569.0
CAPN1 8563.0
ACTG1 8562.0
WAS 8560.0
TLN1 8525.0
ARRB2 8490.0
RHOG 8487.0
PSMB7 8485.0
FGR 8478.0
TFDP1 8470.0
PTEN 8460.0
ADORA2B 8437.0
DNAJC3 8435.0
PSMD4 8402.0
CLTA 8376.0
WASF2 8369.0
AP3B1 8365.0
ENTPD1 8360.0
CHMP3 8349.0
BAG4 8328.0
GNB1 8294.0
ITGB3 8291.0
TXN 8285.0
FN1 8284.0
ARPC3 8277.0
COMT 8273.0
PSME3 8251.0
PPP2CA 8234.0
JAK3 8219.0
TXNRD1 8192.0
PAK2 8185.0
EGF 8179.0
CAST 8164.0
C1GALT1C1 8153.0
IQGAP1 8152.0
PTPN12 8151.0
TRIM27 8142.0
GNB2 8141.0
GBE1 8137.0
MYD88 8136.0
ATG7 8134.0
IL6R 8132.0
CHSY1 8116.0
ADAM17 8110.0
PSMB5 8101.0
GAB2 8099.0
STAT3 8098.0
SLC12A6 8097.0
GNAI2 8075.0
HSPA1A 8071.0
ATP6V1H 8064.0
MAP1LC3B 8043.0
AP2S1 8026.0
C3AR1 8012.0
VPS37C 8010.0
H2BC5 8003.0
NCOR2 7985.0
TAF12 7977.0
GAA 7968.0
CHUK 7966.0
PSEN1 7961.0
GNAI3 7953.0
H2AC6 7934.0
NUP214 7921.0
PRKAR1B 7918.0
H2BC11 7912.0
GNAS 7909.0
NOTCH3 7899.0
VAV1 7896.0
TBL1X 7887.0
RAF1 7879.0
NEDD4L 7875.0
ACTR2 7870.0
AKT1S1 7865.0
NUS1 7864.0
PSMD6 7846.0
PSTPIP1 7841.0
FGFR1OP2 7834.0
ACTR3 7818.0
PIK3AP1 7811.0
LYN 7809.0
SLC24A4 7789.0
TSG101 7786.0
CSNK1A1 7766.0
GSK3A 7760.0
MPDU1 7751.0
DYNC1I2 7735.0
CAPNS1 7729.0
DOCK2 7725.0
GUSB 7723.0
PPP2CB 7712.0
SLC40A1 7696.0
CASP9 7685.0
NCKAP1L 7673.0
CSF2RB 7661.0
VPS25 7638.0
P2RX4 7630.0
MAP3K11 7626.0
SH3GL1 7625.0
PSMD9 7620.0
ARSB 7572.0
POLR2E 7563.0
H2BC18 7547.0
CDC42 7537.0
ADAMTSL4 7530.0
HNRNPK 7522.0
ELOC 7519.0
ARPC4 7516.0
H2AC11 7513.0
GP9 7506.0
SLC9A9 7500.0
MAPK1 7493.0
ROCK1 7489.0
CCND3 7487.0
ELOB 7482.0
CBL 7480.0
GP1BB 7470.0
VEGFA 7467.0
NCKAP1 7462.0
CFP 7445.0
PSMD2 7411.0
MVB12A 7400.0
ARPC2 7390.0
H2BC4 7389.0
BCL2L11 7384.0
IL18 7381.0
ABCD1 7346.0
GNB4 7336.0
SHOC2 7333.0
ANTXR2 7331.0
PSMA1 7329.0
VCL 7328.0
DOCK1 7314.0
ELOA 7312.0
RAP1A 7305.0
H2BC17 7285.0
AP2A2 7257.0
PSMD1 7241.0
SLC35A1 7225.0
TAF13 7217.0
BTK 7206.0
RXFP2 7189.0
RPL26L1 7176.0
PSMB3 7171.0
GYS1 7157.0
IL1RAP 7150.0
SLC7A7 7123.0
TAF10 7110.0
RAB5A 7103.0
GALNS 7102.0
EXT1 7098.0
PSMA7 7096.0
TYK2 7087.0
ABI1 7082.0
GTF2A2 7066.0
PPP1CB 7064.0
BRK1 7032.0
PRDX1 7030.0
F8 7022.0
PSMC1 7021.0
STAT5A 6965.0
DYNC1LI1 6941.0
SPRED2 6936.0
SLC22A5 6929.0
STAT5B 6925.0
CYBA 6922.0
BAD 6892.0
SUMO1 6889.0
VCP 6886.0
MAP2K4 6866.0
KDM7A 6855.0
SEL1L 6847.0
SLC2A9 6834.0
AP2A1 6832.0
PSMB6 6813.0
WASF3 6808.0
NFKBIA 6807.0
MAP2K2 6794.0
PPP2R5B 6774.0
UBE2E1 6759.0
XRCC4 6758.0
ST6GALNAC2 6746.0
PRKAR2B 6741.0
AP1M1 6711.0
H3C15 6699.5
MYO5A 6693.0
MYH9 6685.0
POLR2J 6671.0
PSMF1 6659.0
E2F3 6650.0
VWF 6641.0
UBB 6639.0
SDC4 6637.0
PSMC6 6635.0
GSK3B 6634.0
INSL3 6594.0
LMBRD1 6582.0
MUC1 6573.0
PSMD12 6556.0
PDCD6IP 6528.0
BECN1 6516.0
GALNT1 6508.0
GNG11 6495.0
RNF185 6491.0
VPS37A 6467.0
AHCYL1 6456.0
MYO9B 6424.0
CTNNB1 6408.0
ABCB6 6405.0
FOXO4 6391.0
YWHAB 6385.0
E2F1 6343.0
CALR 6340.0
PPP1CC 6330.0
TICAM1 6307.0
LTF 6306.0
LRRFIP1 6302.0
MMADHC 6291.0
APH1B 6280.0
GP1BA 6279.0
NFKB1 6277.0
SLC25A6 6264.0
ELMO1 6258.0
MGAT1 6257.0
PSMD11 6231.0
GOLGA2 6203.0
AGGF1 6191.0
VTA1 6185.0
CTDP1 6180.0
SH3KBP1 6173.0
PRKAR2A 6166.0
ANAPC11 6161.0
STAM2 6159.0
ROCK2 6138.0
PDPK1 6136.0
EP300 6129.0
HDAC7 6122.0
ABCA1 6109.0
PIK3CD 6046.0
RLN3 6033.0
AREG 5977.0
SNF8 5973.0
PSMA6 5970.0
PSMD7 5963.0
DYNLL1 5952.0
THBS1 5951.0
PSMD13 5948.0
CD9 5940.0
SGSH 5912.0
PPP2R5A 5897.0
BRD4 5892.0
NCOR1 5887.0
ADM2 5881.0
PDGFRA 5858.0
PGM1 5843.0
ITPR2 5842.0
MSH3 5834.0
ST3GAL4 5781.0
GTF2E2 5767.0
PSMD8 5757.0
CHMP1A 5756.0
SEC13 5748.0
ALG14 5746.0
BIN2 5745.0
PSENEN 5735.0
TPST2 5725.0
CHMP2B 5714.0
WIPF2 5713.0
GAB1 5679.0
DVL3 5656.0
TIRAP 5640.0
ABCC6 5615.0
G6PC 5568.0
CANX 5528.0
CHMP6 5499.0
HDAC2 5482.0
ETV6 5443.0
GTF2F2 5434.0
RPS9 5421.0
MAML1 5404.0
SDC2 5397.0
H2BC9 5394.0
GCLM 5391.0
BRAP 5387.0
XRCC5 5384.0
IKBKG 5377.0
NRAS 5363.0
PSMA2 5339.0
LIG4 5316.0
ACACA 5315.0
PTPN11 5314.0
H2BC15 5312.0
FXR1 5308.0
POLR2L 5305.0
PDGFA 5293.0
NOTCH2 5272.0
ADCY4 5270.0
GGCX 5237.0
CALCRL 5232.0
SLC3A2 5222.0
PRKCSH 5220.0
CSK 5219.0
VPS4B 5212.0
CDK7 5211.0
SNW1 5201.0
SLC29A3 5197.0
CORO1A 5178.0
MVB12B 5175.0
GRSF1 5169.0
RAE1 5164.0
RAC2 5163.0
TGFB1 5153.0
CCNE2 5143.0
CTSG 5115.0
UBE2C 5101.0
MAPKAP1 5057.0
SYT1 5056.0
GALE 5026.0
TRAK1 5022.0
HBEGF 5013.0
PIK3R2 5010.0
ELL 5009.0
PLCG2 5006.0
SLC17A5 4989.0
H2AC20 4972.0
CDC25C 4969.0
FAM114A2 4963.0
KPNA4 4957.0
GTF2F1 4951.0
CHMP5 4943.0
SMAD2 4905.0
VAV3 4894.0
IL1B 4807.0
SLC9A6 4781.0
FDXR 4766.0
HDAC11 4756.0
CBX1 4751.0
UBE2S 4746.0
DPM2 4721.0
HDAC5 4710.0
NOTCH1 4704.0
HDAC3 4673.0
PIK3CA 4629.0
PSMD3 4618.0
POLR2F 4604.0
PPP2R1A 4589.0
TBL1XR1 4556.0
NUP50 4521.0
HGS 4513.0
CDKN1A 4511.0
RPL3L 4503.0
SLC39A4 4464.0
PTK2 4462.0
SLC16A1 4455.0
UBC 4439.0
TPMT 4422.0
ELMO2 4397.0
SOD2 4390.0
PARP4 4362.0
DUSP6 4357.0
SEM1 4348.0
NMT1 4328.0
MDM2 4312.0
RFT1 4309.0
GNG8 4296.0
B4GALT1 4292.0
LRP5 4289.0
SKP1 4287.0
DYNC1LI2 4273.0
CTSL 4231.0
CASP1 4224.0
VPS28 4199.0
RHBDF2 4197.0
DYNC1I1 4187.0
UNC93B1 4170.0
KSR1 4167.0
HYAL1 4164.0
SHC1 4161.0
EPS15 4138.0
APH1A 4133.0
SLC22A18 4112.0
CDC37 4096.0
PSMB2 4084.0
CTBP2 4080.0
PDZD3 4005.0
AP1G1 3987.0
SRD5A3 3971.0
SSPO 3959.0
RBX1 3934.0
FGF2 3920.0
G6PC3 3915.0
TGFBR2 3914.0
VPS37B 3908.0
LMNA 3887.0
CYP27A1 3877.0
GTF2H5 3874.0
NELFE 3860.0
SND1 3849.0
TRIM24 3806.0
MMUT 3791.0
NRG1 3750.0
JUN 3722.0
KRAS 3702.0
STRN 3695.0
VHL 3674.0
KIAA1549 3618.0
AKT1 3614.0
ERCC2 3547.0
GTF2B 3515.0
POLR2G 3508.0
P2RX7 3475.0
PRDX2 3428.0
PSMD5 3426.0
CREBBP 3423.0
RLBP1 3401.0
PSMB1 3374.0
ZMYM2 3368.0
GNAI1 3329.0
MYO1C 3310.0
ADORA2A 3293.0
SLC35A2 3255.0
APC 3240.0
TBK1 3229.0
RAP1B 3206.0
MRC1 3109.0
NUP98 3101.0
AVPR1A 3091.0
RNGTT 3088.0
HDAC8 3079.0
NUP37 3074.0
ABCG8 3056.0
DERL2 3041.0
NF1 3036.0
GTF2H2 2984.0
CDC26 2923.0
CDC25A 2911.0
GNAZ 2909.0
SUPT4H1 2890.0
CCNK 2877.0
SLC12A1 2870.0
POMC 2855.0
RAMP3 2854.0
ATP1A1 2813.0
SLC35C1 2750.0
GTF2A1 2713.0
SEMA5B 2706.0
JAK2 2691.0
EPGN 2662.0
ALG12 2659.0
ARAF 2644.0
PSMD14 2611.0
SDC3 2599.0
PSMC2 2598.0
DPM3 2577.0
PSMB4 2523.0
SLC27A4 2479.0
KPNB1 2430.0
PPP2R5D 2421.0
CFTR 2416.0
CHMP4A 2400.0
MYC 2304.0
GTF2E1 2287.0
HDAC10 2280.0
SFPQ 2253.0
CLCN6 2232.0
DPAGT1 2163.0
TAF7 2139.0
RPS27L 2061.0
TSHR 2051.0
ARRB1 1998.0
MTRR 1994.0
PSMC3 1976.0
CAMK2G 1921.0
EREG 1888.0
CCNC 1877.0
HGSNAT 1867.0
FDX1 1854.0
AP1M2 1832.0
GALNT3 1805.0
RCC1 1766.0
SFTPB 1754.0
IRS1 1741.0
UGT1A1 1670.0
MAP2K7 1654.0
ALG6 1653.0
MGAT2 1633.0
PIK3C3 1619.0
POLR2C 1616.0
TGFBR1 1585.0
DPM1 1567.0
PSMD10 1559.0
SUGT1 1544.0
PTGER2 1463.0
RPIA 1441.0
PMM2 1394.0
HDAC9 1359.0
HSP90AA1 1326.0
BRAF 1308.0
KPNA1 1296.0
GP5 1295.0
STAM 1285.0
HEXA 1261.0
SLC34A2 1253.0
TAF9 1250.0
NEIL3 1194.0
GCK 1193.0
CHST14 1138.0
UBA52 1121.0
CAPN2 1064.0
ELK1 1040.0
SYVN1 992.0
KPNA3 923.0
GNG3 890.0
ADAMTSL3 855.0
CUL5 834.0
SLC25A5 826.0
VPS4A 784.0
CCNH 774.0
NUP62 769.0
GSS 715.0
RPS6KB2 700.0
ERLEC1 698.0
POMT2 624.0
SLC7A9 622.0
RDH5 591.0
HDAC1 587.0
LRP6 577.0
WIPF1 569.0
GNB5 512.0
NR3C1 511.0
ST3GAL3 505.0
ZCRB1 487.0
AHCY 466.0
SYT2 461.0
AKT2 433.0
RPS4Y1 424.0
POLR2I 396.0
MLST8 376.0
NELFB 374.0
IGHV1-2 360.0
NCKIPSD 328.0
KREMEN2 316.0
EEF2 306.0
WASL 299.0
AVPR2 291.0
SLC11A2 260.0
IGHV2-5 230.0
ABL1 226.0
ADCY9 123.0
HMGA1 117.0
IGHV3-53 103.0
RPL36AL 32.0
RPLP1 19.0
DVL1 0.0
CD86 -14.0
CXCR4 -45.0
FMOD -59.0
ITGB1 -94.0
BAIAP2 -215.0
PPP2R1B -241.0
RPS24 -263.0
DCXR -290.0
FAU -362.0
FMO3 -371.0
IGHV3-7 -441.0
ERBB3 -472.0
TNKS2 -499.0
PABPN1 -526.0
ERBIN -574.0
MAML2 -582.0
PSMA4 -616.0
IGHV1-46 -618.0
TLR7 -625.0
ST6GALNAC4 -629.0
CDC27 -651.0
IGHV3-48 -668.0
PPP2R5E -680.0
GGT5 -695.0
FAM131B -734.0
GPR83 -743.0
UBE2I -764.0
IGKV3-11 -781.0
TSC2 -804.0
RANBP2 -820.0
C1QBP -822.0
PSMC5 -863.0
GPS2 -889.0
TCEA1 -943.0
RPL15 -963.0
GANAB -986.0
IGKV1-39 -989.0
RPLP0 -1000.0
IGLV7-46 -1016.0
CDK5R1 -1089.0
NFKB2 -1165.0
IGKV1-5 -1184.0
XPO1 -1185.0
RPL8 -1187.0
ALG2 -1259.0
ALG3 -1263.0
IGLV2-8 -1294.0
IGKV5-2 -1298.0
SLC36A2 -1307.0
IGHV3-23 -1317.0
CREB1 -1378.0
EXT2 -1405.0
RPS26 -1430.0
IGHV3-13 -1443.0
RPL28 -1462.0
IGLV2-18 -1524.0
IGKV1-16 -1528.0
IGLV4-69 -1559.0
CP -1561.0
IGKV1D-39 -1574.0
SLC34A1 -1602.0
ADCY6 -1608.0
RPL22L1 -1619.0
DUSP10 -1650.0
TAF4 -1698.0
PRELP -1738.0
RPS13 -1749.0
POLR2K -1783.0
RELA -1803.0
IGHV1-69 -1822.0
TAF3 -1850.0
SV2B -1857.0
RBBP4 -1870.0
RPL9 -1872.0
NRG4 -1875.0
IGLV10-54 -1884.0
RPL7 -1955.0
CDK8 -1971.0
IGLV1-36 -2030.0
IGKV2-30 -2045.0
ABCC2 -2079.0
CALM1 -2081.0
RPS8 -2083.0
IGLV7-43 -2089.0
VPS33B -2091.0
IGLV3-19 -2111.0
ANAPC16 -2123.0
IGHV3-11 -2134.0
SLC33A1 -2142.0
GNG4 -2154.0
MSH6 -2180.0
MUCL1 -2211.0
FZR1 -2233.0
GTF2H3 -2235.0
DHDDS -2236.0
AP1S2 -2261.0
IGKV3-15 -2297.0
GNB3 -2397.0
SUZ12 -2409.0
KAT2B -2414.0
IGKV1-33 -2424.0
ALDOB -2431.0
HTR7 -2438.0
IGHV3-30 -2484.0
POLR2B -2523.0
IGKV4-1 -2532.0
HLA-A -2573.0
NEURL1B -2586.0
TAF9B -2599.0
IDS -2621.0
DPEP2 -2705.0
AP2B1 -2709.0
PLK2 -2748.0
PAPSS2 -2810.0
RPL27 -2855.0
IGKV1-17 -2871.0
IGLV2-23 -2878.0
IGLV6-57 -2885.0
IGHV4-59 -2892.0
SLC26A2 -2893.0
DPEP3 -2894.0
ADCY2 -2896.0
IGLV2-11 -2905.0
GTF2H1 -2913.0
GTF2H4 -2916.0
B3GAT3 -2928.0
TAF11 -2938.0
POLR2H -2942.0
STX1B -2952.0
TLR10 -2961.0
MUC6 -2977.0
SV2C -2979.0
IGHV3-33 -2988.0
PHB -2995.0
MIB1 -2998.0
RPL39 -3006.0
IGHV4-34 -3016.0
NUP85 -3049.0
MOGS -3051.0
PSMB8 -3076.0
IGKV3-20 -3085.0
POLR2A -3092.0
IGHV2-70 -3138.0
MUC4 -3191.0
DUSP7 -3211.0
IGLV1-44 -3258.0
ADCY7 -3286.0
FGFR4 -3293.0
RPL23 -3314.0
RPL6 -3354.0
KSR2 -3361.0
HRAS -3382.0
RPL13 -3431.0
FRS2 -3433.0
ADAMTS5 -3479.0
IGHG3 -3481.0
THSD4 -3560.0
RPL4 -3582.0
ALG11 -3593.0
RPL29 -3611.0
ALG8 -3635.0
DOLK -3639.0
RPL7A -3665.0
RPS15 -3673.0
CYP27B1 -3807.0
CYP24A1 -3820.0
ADAMTS17 -3827.0
CD19 -3843.0
NELFA -3886.0
IGKV3D-20 -3894.0
CDK9 -3927.0
RPL37A -3946.0
KANK1 -3964.0
MYO18A -3970.0
DYNLL2 -3980.0
POLR2D -4024.0
STX1A -4052.0
VAV2 -4055.0
PIK3R4 -4062.0
GOLGA4 -4064.0
RPS21 -4079.0
MUC16 -4104.0
KCNJ11 -4105.0
IGLV3-1 -4159.0
FGF7 -4247.0
GPC2 -4280.0
CYP7B1 -4294.0
C1GALT1 -4297.0
CHST6 -4347.0
AMN -4361.0
ADAMTS13 -4374.0
PARP9 -4400.0
HTR6 -4426.0
IGKC -4428.0
XRCC6 -4471.0
B3GALT6 -4474.0
RPS2 -4499.0
TAF5 -4514.0
RPL31 -4541.0
CSPG4 -4549.0
IGHV4-39 -4582.0
ACY1 -4587.0
MUC5B -4613.0
GPC1 -4627.0
RPS16 -4669.0
RPS3A -4694.0
RPS28 -4713.0
SLC5A2 -4725.0
RPL5 -4728.0
GPC4 -4730.0
IGLV3-21 -4735.0
RPL22 -4740.0
ABCC9 -4745.0
BANF1 -4752.0
NAGLU -4761.0
CNKSR2 -4781.0
IGLV1-40 -4788.0
MAN1B1 -4871.0
BTRC -4924.0
IGLV3-25 -4933.0
IGLV1-51 -4956.0
PARP6 -4959.0
RPS7 -4968.0
ANAPC10 -5000.0
CDK2 -5006.0
FDX2 -5019.0
AKAP9 -5020.0
TRIM28 -5056.0
RPL18 -5080.0
CRHR2 -5119.0
ANAPC7 -5181.0
GNE -5192.0
GNG7 -5198.0
CCNT2 -5205.0
NOTCH4 -5229.0
CDKN2A -5236.0
SLC6A20 -5271.0
IGLC7 -5281.0
PSMA3 -5285.0
RPL36 -5287.0
SLC5A5 -5330.0
FGFR1 -5352.0
IKBKB -5386.0
CD4 -5406.0
IGLV8-61 -5427.0
RPL17 -5431.0
ABCB4 -5440.0
IGKV1-12 -5446.0
RPS14 -5463.0
NOXA1 -5464.0
IGLC3 -5477.0
SLC2A10 -5478.0
IGLC2 -5510.0
PMS2 -5514.0
AP1S3 -5522.0
NUP42 -5564.0
TRAF3 -5576.0
MAMLD1 -5584.0
NHLRC1 -5628.0
IGKV2D-28 -5634.0
B4GAT1 -5642.0
RPS5 -5691.0
SOS1 -5700.0
PSMB10 -5735.0
RPS15A -5742.0
RPS10 -5793.0
RPL24 -5799.0
IGKV2-28 -5808.0
IDUA -5830.0
RPL38 -5840.0
NCBP1 -5853.0
IGLV5-45 -5869.0
IGLV3-27 -5874.0
LARGE1 -5910.0
RPS3 -5914.0
TAF2 -5945.0
MUC20 -5962.0
NT5E -5964.0
RPS12 -5987.0
TLR9 -5999.0
RPL35A -6015.0
IGLV1-47 -6018.0
DUT -6046.0
PSMA5 -6053.0
SEH1L -6069.0
RPL18A -6070.0
CDC16 -6071.0
PSME4 -6087.0
CPSF6 -6137.0
VIPR1 -6156.0
IGLC1 -6157.0
RPS6 -6160.0
MRAS -6172.0
ENTPD5 -6179.0
TCF7L2 -6185.0
CRBN -6190.0
IGHG1 -6201.0
RPS17 -6247.0
RPL27A -6257.0
RPL11 -6261.0
NELFCD -6277.0
RPL19 -6281.0
RPS4X -6285.0
RPS23 -6292.0
NUP153 -6321.0
RPSA -6323.0
SLC37A4 -6333.0
RPS25 -6365.0
FOXO6 -6367.0
RPL37 -6375.0
RNF5 -6413.0
TAF15 -6454.0
CTBP1 -6456.0
RPL21 -6458.0
GFPT1 -6462.0
CDK6 -6465.0
FZD7 -6508.0
FZD6 -6525.0
RPL10 -6534.0
H2BU1 -6555.0
FBXW7 -6600.0
RPL26 -6612.0
FGF23 -6622.0
GPR15 -6636.0
CNTRL -6639.0
ANAPC4 -6644.0
DUSP16 -6655.0
RPL10A -6686.0
RPL32 -6709.0
RPL14 -6710.0
SUPT5H -6716.0
ADAMTS14 -6719.0
NR4A1 -6756.0
FGFR1OP -6758.0
PPIA -6766.0
RAN -6791.0
PDCD1 -6792.0
RPL34 -6802.0
SPRED3 -6835.0
CD80 -6841.0
VPS36 -6848.0
HSP90AB1 -6863.0
RPL41 -6866.0
MLH1 -6872.0
MMACHC -6876.0
SLC35D1 -6904.0
KPNA2 -6910.0
IGHG4 -6911.0
B2M -6920.0
RPS27A -6938.0
TUBB -6956.0
RPS19 -6965.0
CCND1 -6970.0
RPL30 -7020.0
TPR -7028.0
RPL12 -7053.0
ADAMTS6 -7055.0
BCR -7071.0
RPLP2 -7087.0
CNKSR1 -7089.0
GPBAR1 -7132.0
FZD8 -7138.0
NAPEPLD -7168.0
POM121C -7188.0
KHK -7193.0
RPS11 -7243.0
IGHG2 -7250.0
THSD1 -7288.0
SLC34A3 -7335.0
TAF6 -7352.0
IGLV3-12 -7358.0
B4GALT7 -7367.0
RPL36A -7376.0
DAG1 -7379.0
ANAPC2 -7407.0
ST3GAL1 -7442.0
DERL3 -7467.0
CUBN -7513.0
TRAT1 -7535.0
PSMA8 -7606.0
ITPR1 -7629.0
ALG13 -7645.0
ADRB1 -7674.0
CYSLTR1 -7675.0
DYNC1H1 -7685.0
PSEN2 -7718.0
SIGMAR1 -7732.0
RPS18 -7744.0
NUP133 -7762.0
HSPG2 -7779.0
ERCC3 -7783.0
GNG2 -7795.0
ZFYVE9 -7848.0
OGG1 -7915.0
FIP1L1 -7928.0
RPS29 -7940.0
PCCB -7976.0
SBSPON -8022.0
RAMP1 -8039.0
TAF4B -8069.0
RPL35 -8092.0
NTHL1 -8134.0
NEIL1 -8179.0
CD8B -8188.0
CDKN1B -8207.0
RPL13A -8212.0
ADCY5 -8235.0
HES1 -8266.0
SKP2 -8279.0
POM121 -8299.0
SLC3A1 -8302.0
ADAMTSL5 -8317.0
HDAC6 -8337.0
IGLV2-14 -8345.0
SMAD4 -8351.0
LFNG -8372.0
ADAMTS16 -8387.0
AAAS -8389.0
PARP10 -8400.0
CTNND1 -8403.0
PARP8 -8409.0
ABCD4 -8420.0
TAF1 -8476.0
NUP54 -8479.0
PACS1 -8486.0
RPL3 -8561.0
PDGFB -8577.0
THSD7A -8596.0
FGF22 -8607.0
CBLL1 -8620.0
VAMP1 -8625.0
RLN2 -8636.0
SPRED1 -8639.0
PCCA -8664.0
POMT1 -8665.0
MNAT1 -8687.0
PML -8693.0
TNKS -8738.0
FGF9 -8761.0
ALG1 -8792.0
CHMP7 -8802.0
RPL39L -8805.0
SRC -8820.0
CCR5 -8861.0
RPS20 -8886.0
DERL1 -8963.0
CYSLTR2 -8970.0
MCCC1 -8976.0
KLKB1 -9019.0
UVRAG -9024.0
MMAB -9046.0
EIF2AK2 -9116.0
ESR1 -9122.0
PTGIR -9126.0
PSMC4 -9127.0
TBP -9167.0
GALT -9201.0
S1PR1 -9211.0
ESR2 -9250.0
HHAT -9301.0
SLC35A3 -9305.0
EED -9348.0
CPSF4 -9416.0
MAPK8 -9428.0
ICOS -9434.0
FOXO1 -9465.0
CCNT1 -9469.0
SEMA5A -9495.0
PIK3R1 -9505.0
NUP43 -9517.0
NPM1 -9532.0
NCBP2 -9558.0
RPL23A -9567.0
TXNIP -9600.0
RANBP1 -9657.0
RICTOR -9670.0
CD320 -9704.0
EZH2 -9741.0
PSIP1 -9743.0
HEY2 -9752.0
RPS27 -9756.0
ALG9 -9766.0
MTOR -9767.0
DDX5 -9843.0
GALNT12 -9866.0
IMPDH2 -9916.0
CYP2R1 -9918.0
GPR150 -9942.0
CAMK4 -9956.0
PSME1 -9991.0
ZC3HAV1 -10064.0
PORCN -10074.0
CD28 -10202.0
NUP155 -10233.0
SPON1 -10262.0
AXIN1 -10285.0
ITPR3 -10308.0
PSME2 -10336.0
CYFIP2 -10367.0
NUP107 -10421.0
PRKX -10428.0
SIN3A -10493.0
NUP160 -10557.0
DAXX -10575.0
IPO5 -10591.0
FEN1 -10593.0
NUP35 -10611.0
GPR25 -10677.0
MUC12 -10704.0
NUP210 -10726.0
EPM2A -10751.0
MPI -10760.0
KAT2A -10771.0
ADAMTS4 -10829.0
MECP2 -10855.0
SV2A -10890.0
P2RY11 -10907.0
ABI2 -10915.0
JAK1 -10955.0
MPRIP -10959.0
ANAPC5 -10967.0
KIT -11004.0
MUTYH -11016.0
ADAMTS10 -11036.0
ITGA4 -11043.0
JAG2 -11044.0
LIG1 -11053.0
SLC24A1 -11057.0
MIB2 -11073.0
RIPK1 -11074.0
RNMT -11086.0
PLCG1 -11120.0
DVL2 -11152.0
SSRP1 -11162.0
TENT4A -11168.0
MC1R -11184.0
SERPING1 -11197.0
SLC2A1 -11236.0
CDK4 -11256.0
PPP2R5C -11265.0
PEBP1 -11270.0
AMER1 -11301.0
CDC23 -11304.0
NUP205 -11321.0
PSMB9 -11324.0
CUL1 -11330.0
SLC12A3 -11355.0
SUPT16H -11359.0
NUP88 -11397.0
H2AW -11403.0
ADAMTS1 -11438.0
DBP -11441.0
NCK1 -11454.0
MMAA -11476.0
MSH2 -11484.0
CDH1 -11500.0
TLR3 -11525.0
CD3G -11526.0
SFTPD -11535.0
PDGFRB -11545.0
WDR48 -11565.0
NUP93 -11620.0
NUP188 -11624.0
NEURL1 -11633.0
DUSP8 -11639.0
FZD4 -11650.0
FYN -11675.0
GCLC -11691.0
GPR20 -11696.0
PTGER4 -11697.0
CCNE1 -11707.0
HLCS -11710.0
RANGAP1 -11722.0
STAT1 -11727.0
CCND2 -11734.0
SLC4A4 -11735.0
SMAD3 -11745.0
ABCA3 -11756.0
B3GLCT -11758.0
PARP1 -11764.0
AGRN -11770.0
VAMP2 -11779.0
FGFR2 -11785.0
CAMK2D -11816.0
SLC20A2 -11823.0
PARP16 -11830.0
LCK -11838.0
AKT3 -11849.0
MCCC2 -11857.0
SLC25A4 -11858.0
PARP14 -11869.0
DLL1 -11885.0
SCT -11886.0
ADRB2 -11892.0
KPNA5 -11893.0
RNF213 -11905.0
CDKN1C -11931.0
POMGNT1 -11937.0
PRKACB -11959.0
ANAPC1 -11962.0
APOBEC3G -11967.0
PRR5 -11985.0
MTR -11996.0
CYP2U1 -12000.0
FCGR3A -12005.0
PIK3R3 -12015.0
CDC25B -12017.0
PTGDR -12021.0
ISG15 -12032.0
NMT2 -12035.0
ST6GAL1 -12052.0
GNGT2 -12086.0
GIPR -12100.0
AGK -12120.0
RNF43 -12121.0
YES1 -12142.0
VIPR2 -12153.0
RBBP7 -12155.0
BTD -12170.0
NDC1 -12173.0
C3 -12262.0
CYP4F22 -12271.0
SPON2 -12276.0
ERBB2 -12320.0
CD247 -12345.0
TFDP2 -12364.0
FASLG -12371.0


Transport of small molecules

Transport of small molecules
1288
set Transport of small molecules
setSize 561
pANOVA 1.57e-14
s.dist 0.19
p.adjustANOVA 1.07e-12



Top enriched genes

Top 20 genes
GeneID Gene Rank
MICU1 9473
CYB5R1 9460
PRKACA 9429
ATP6V0A1 9423
FBXL5 9410
ASPH 9399
SLC1A3 9389
CA1 9380
GNG10 9349
MCU 9320
ATP6V1A 9302
SLC36A1 9292
AQP9 9282
TRPV4 9269
ANO10 9254
ATP6V0D1 9245
PCSK9 9208
BSG 9172
SLC11A1 9169
SLC4A1 9141

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MICU1 9473
CYB5R1 9460
PRKACA 9429
ATP6V0A1 9423
FBXL5 9410
ASPH 9399
SLC1A3 9389
CA1 9380
GNG10 9349
MCU 9320
ATP6V1A 9302
SLC36A1 9292
AQP9 9282
TRPV4 9269
ANO10 9254
ATP6V0D1 9245
PCSK9 9208
BSG 9172
SLC11A1 9169
SLC4A1 9141
ATP6V0C 9127
SLC22A4 9124
TRPM2 9102
FURIN 9075
ATP6V1B2 9057
HBB 9054
ATP6V1D 9047
SLC2A3 9021
CLTC 9000
HBA1 8990
ADCY3 8984
PARL 8958
ERLIN2 8928
DMTN 8924
NCEH1 8922
SLC6A6 8907
OS9 8898
SLC31A1 8874
ERLIN1 8869
SLC22A15 8855
GNG5 8815
SLC16A3 8783
HFE 8777
PCSK6 8740
SLC39A1 8736
RAB11A 8688
FTL 8665
AP2M1 8627
PRKAR1A 8607
CYB5R2 8600
ATP6V0B 8598
ATP6V0E1 8596
ATP6V1C1 8539
SLC44A1 8526
SLC15A3 8517
ALAD 8514
PSMB7 8485
SLCO2B1 8450
SLC8A1 8444
P4HB 8440
CYB5R4 8421
PSMD4 8402
ATP11A 8394
CLTA 8376
SLC39A8 8339
SLCO3A1 8338
SLC27A1 8305
GNB1 8294
HMOX1 8278
PSME3 8251
SOAT1 8231
ATP6AP1 8160
GNB2 8141
SLC43A2 8105
PSMB5 8101
SLC12A6 8097
ATP6V1H 8064
ANO6 8048
ATP2A2 8038
ATP6V1E1 8035
AP2S1 8026
SLC26A6 7982
SLC30A1 7974
SLC9A1 7969
PRKAR1B 7918
GNAS 7909
RAF1 7879
NEDD4L 7875
SLC35D2 7872
VDAC2 7857
PSMD6 7846
SLC24A4 7789
LCN2 7755
SLC8B1 7746
MCOLN1 7740
HDLBP 7702
SLC40A1 7696
BEST1 7678
SLC36A4 7655
SGK3 7646
PSMD9 7620
RUNX1 7529
ATP2C2 7512
SLC9A9 7500
AQP1 7476
SLC4A2 7458
SLC6A9 7452
ABCC4 7434
NR1H2 7415
PSMD2 7411
FXYD6 7391
APOBR 7351
ABCD1 7346
PLTP 7338
GNB4 7336
PSMA1 7329
AQP10 7294
CLCN3 7261
AP2A2 7257
PSMD1 7241
SLC35A1 7225
EMB 7219
TCIRG1 7188
PSMB3 7171
FKBP1B 7154
SLC7A7 7123
TTYH3 7122
PSMA7 7096
MMGT1 7078
OSTM1 7036
BEST3 7024
PSMC1 7021
ATP8B4 6970
SLC22A5 6929
VCP 6886
SEL1L 6847
SLC2A9 6834
AP2A1 6832
CTNS 6817
PSMB6 6813
ATP7B 6800
CLCN5 6792
TPCN2 6751
EIF2S3 6747
PRKAR2B 6741
STOM 6704
TRPM4 6679
PSMF1 6659
UBB 6639
PSMC6 6635
PSMD12 6556
SRI 6554
LIPA 6505
GNG11 6495
RNF185 6491
NEDD8 6482
SAR1B 6479
SLC1A5 6476
ABCB6 6405
RYR2 6400
ATP1B2 6378
SLC28A3 6309
SLC38A2 6297
SLC25A6 6264
PSMD11 6231
LDLR 6183
EIF2S2 6175
PRKAR2A 6166
SLC2A14 6117
ABCA1 6109
ANO8 6099
YME1L1 6069
ATP11B 6064
ABCB10 6018
STEAP3 5996
PSMA6 5970
PSMD7 5963
SCARB1 5962
PSMD13 5948
APOA2 5879
ATP6V1F 5878
PSMD8 5757
PEX19 5750
ATP6V1E2 5730
ABCC3 5717
ADD1 5704
CYBRD1 5661
ABCC6 5615
ATP9B 5614
SLC35B3 5546
SLC24A3 5480
NPC2 5458
BSND 5426
UNC79 5414
SLC24A2 5374
SLC22A16 5373
PSMA2 5339
ADCY4 5270
IREB2 5231
WNK1 5224
SLC3A2 5222
TPCN1 5221
SLC29A3 5197
ATP9A 5106
SLC16A7 5083
SLCO4A1 5037
CLCN4 5036
SLC9A8 5001
LRRC8D 4999
SLC17A5 4989
SLC66A1 4965
ABCD3 4933
SLC5A9 4930
FTH1 4902
SLC39A7 4879
ATP2C1 4865
PCSK5 4863
RAB11FIP2 4818
SLC9A6 4781
SLC22A1 4716
ATP8B3 4711
CLCN1 4687
PSMD3 4618
SGK1 4595
TRPM6 4515
SLC39A3 4505
SLC39A4 4464
ANO5 4463
SLC16A1 4455
UBC 4439
SEM1 4348
VDAC1 4347
GNG8 4296
SKP1 4287
EIF2S1 4279
NIPA2 4203
SLC22A18 4112
PSMB2 4084
CUTC 3944
ATP6V1G1 3931
ADD3 3735
SLC15A4 3724
SLC50A1 3692
TSC22D3 3680
ALB 3668
CA2 3570
SLC15A2 3556
SLC35B4 3472
PSMD5 3426
SLC6A12 3414
PSMB1 3374
NIPAL1 3335
SLC35A2 3255
SLCO4C1 3212
ATP13A2 3194
ATP11C 3159
LRRC8B 3157
BEST2 3141
ABCA7 3077
ABCG8 3056
DERL2 3041
SLC7A5 3012
CETP 3003
SLC2A13 2987
MBTPS1 2966
SLC12A1 2870
SLC12A4 2845
CA4 2826
SLC25A18 2815
ATP1A1 2813
ATP10B 2755
SLC35C1 2750
SLC44A2 2700
MAGT1 2613
PSMD14 2611
PSMC2 2598
SLC25A29 2580
LPL 2545
PSMB4 2523
SLC27A4 2479
ABCC5 2477
ATP10D 2433
CFTR 2416
CLCN6 2232
PSMC3 1976
CLCN7 1943
CAMK2G 1921
SLC7A8 1916
SLC8A3 1886
SLC46A1 1882
NIPAL2 1795
WNK2 1613
SLC16A8 1608
PSMD10 1559
TFRC 1524
SLC29A1 1428
TRPC4AP 1263
SLC34A2 1253
RSC1A1 1209
UBA52 1121
TF 1102
ATP1A4 922
SLC17A7 919
GNG3 890
SLC5A12 836
SLC25A5 826
TRPM3 797
ERLEC1 698
ATP7A 694
LIPC 625
SLC7A9 622
LRRC8C 594
ABCC1 576
GNB5 512
VDAC3 436
AHCYL2 425
AVPR2 291
SLC18A2 286
BMP1 268
SLC11A2 260
SMDT1 254
APOE 218
ADCY9 123
LCN15 93
MBTPS2 83
SLC30A6 -3
ABCG2 -77
PHB2 -166
SLC28A2 -181
SCNN1A -222
NIPAL4 -379
APOD -426
SLC30A2 -444
ARL2 -565
UNC80 -568
PSMA4 -616
SLC1A2 -728
PMPCB -803
CLCN2 -812
MICU2 -817
PSMC5 -863
LCAT -884
TTYH1 -893
ATP2A3 -914
SLC6A1 -949
LIPG -1012
SLC1A6 -1034
ABCB8 -1115
SLC36A2 -1307
ATP1B3 -1347
SLC5A11 -1350
SLC13A5 -1420
GLRX3 -1479
CP -1561
SLC34A1 -1602
ADCY6 -1608
ABCA9 -1819
ABCB7 -1842
TRPC6 -1935
ABCC2 -2079
CALM1 -2081
SLC33A1 -2142
GNG4 -2154
ATP6V1C2 -2219
ABCB9 -2228
AQP11 -2381
GNB3 -2397
ANO7 -2410
SLC12A7 -2422
TRPM8 -2445
SLC30A5 -2461
SLC29A4 -2485
ABCA6 -2612
SLC2A6 -2676
SLC22A17 -2703
AP2B1 -2709
SOAT2 -2861
SLC26A2 -2893
ADCY2 -2896
SLC13A4 -2986
PHB -2995
MFSD4B -3031
PSMB8 -3076
SLC47A1 -3233
ADCY7 -3286
ASIC1 -3426
ZDHHC8 -3451
ANGPTL4 -3469
MCUB -3477
TRPM5 -3491
SLC44A5 -3527
NR1H3 -3597
MYLIP -3991
STOML2 -4000
SLC14A2 -4001
KCNJ11 -4105
AMN -4361
VLDLR -4385
SLC30A7 -4455
TTYH2 -4458
LETM1 -4573
SLC43A1 -4611
ATP2A1 -4667
MCOLN3 -4692
SLC16A10 -4715
SLC5A2 -4725
ABCC9 -4745
ATP8A2 -4798
TRPV6 -4904
ABCC10 -4930
ATP2B4 -5030
ATP8B1 -5033
SLC4A5 -5062
GNG7 -5198
WNK3 -5232
SLC6A20 -5271
PSMA3 -5285
SLC5A5 -5330
FXYD1 -5429
ABCB4 -5440
TRPV2 -5458
SLC2A10 -5478
RYR1 -5495
ATP13A1 -5530
ADD2 -5586
SLC5A6 -5629
SCNN1D -5715
SLC7A11 -5719
PSMB10 -5735
FXYD2 -5748
SLC38A5 -5797
SLC2A12 -5930
PSMA5 -6053
SLC9B1 -6075
PSME4 -6087
PMPCA -6127
PDZD11 -6288
AQP7 -6377
SGK2 -6388
RNF5 -6413
SLC39A5 -6434
SLC7A1 -6472
SLC25A22 -6553
CAND1 -6554
MRS2 -6620
SLC7A6 -6690
ARL2BP -6734
SLC14A1 -6749
SLC47A2 -6833
SLC39A14 -6854
SLC35D1 -6904
CLIC2 -6930
RPS27A -6938
SLC2A11 -7005
SLC9A7 -7073
ASIC3 -7185
FXYD7 -7230
MICU3 -7286
LSR -7320
SLC34A3 -7335
SLC26A11 -7413
TRPM7 -7431
DERL3 -7467
CUBN -7513
PSMA8 -7606
SLC4A10 -7713
SLC39A6 -7717
SLC45A3 -7791
GNG2 -7795
SLC9A5 -7799
ATP13A4 -7878
ABCG1 -7961
LMF2 -8018
LRRC8A -8132
SLC26A1 -8174
ADCY5 -8235
ATP2B1 -8286
SLC3A1 -8302
FLVCR1 -8306
SLC9A3 -8347
ACO1 -8450
ABCA5 -8681
BEST4 -8728
CES3 -8917
DERL1 -8963
FXYD3 -8981
ABCA10 -9007
ATP1B1 -9118
PSMC4 -9127
ANO9 -9130
MYO5B -9138
LMF1 -9157
SLC35A3 -9305
LDLRAP1 -9326
TRPC3 -9343
SLC5A10 -9419
ATP6V1G2 -9515
ABCF1 -9531
TRPV1 -9543
SLC1A7 -9612
SLC29A2 -9723
TRPC1 -9736
AQP3 -9760
TFR2 -9789
A2M -9870
RYR3 -9953
PSME1 -9991
SLC4A8 -10101
WWP1 -10106
SLC35B2 -10225
SLC25A10 -10239
SLC39A10 -10306
NIPAL3 -10316
PSME2 -10336
ABCA2 -10376
SPG7 -10555
CYB5RL -10762
AFG3L2 -10807
ATP8B2 -10811
LCN12 -10869
TRPV3 -10996
SLC24A1 -11057
SLC13A3 -11108
ABCD2 -11160
SLC1A4 -11174
SLC5A3 -11186
SLC2A1 -11236
NIPA1 -11316
PSMB9 -11324
CUL1 -11330
SLC12A2 -11346
SLC12A3 -11355
SLC9B2 -11358
SLC38A1 -11417
SLC20A1 -11418
AKAP1 -11442
SLC41A1 -11497
ATP1A3 -11543
ATP6V0E2 -11555
MCOLN2 -11638
SLC18A1 -11684
SLC4A4 -11735
SLC2A8 -11749
ABCA3 -11756
CAMK2D -11816
HMOX2 -11819
SLC20A2 -11823
ATP8A1 -11842
SLC25A4 -11858
ANKH -11883
SLC4A7 -11915
PRKACB -11959
PEX3 -12083
GNGT2 -12086
ATP6V0A2 -12211
NPC1 -12217
ATP10A -12218
ABCB1 -12224
SLC25A26 -12252
SLC4A3 -12321
SLC41A2 -12379


Toll Like Receptor 4 (TLR4) Cascade

Toll Like Receptor 4 (TLR4) Cascade
1239
set Toll Like Receptor 4 (TLR4) Cascade
setSize 121
pANOVA 3.21e-14
s.dist 0.399
p.adjustANOVA 2.08e-12



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A12 9515
CD36 9444
ITGAM 9398
NKIRAS2 9353
DUSP3 9280
UBE2D1 9187
APP 9177
IRAK3 9107
MAPK14 9104
TLR2 9103
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
ITGB2 8942
TLR1 8932
MAP2K6 8887
TLR6 8840
LY96 8795
MAP2K3 8748

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A12 9515
CD36 9444
ITGAM 9398
NKIRAS2 9353
DUSP3 9280
UBE2D1 9187
APP 9177
IRAK3 9107
MAPK14 9104
TLR2 9103
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
ITGB2 8942
TLR1 8932
MAP2K6 8887
TLR6 8840
LY96 8795
MAP2K3 8748
UBE2D3 8640
NOD2 8442
MAPKAPK3 8382
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966
PELI3 7716
PPP2CB 7712
RPS6KA1 7695
LY86 7667
TANK 7502
MAPK1 7493
BTK 7206
DNM3 7045
TAB2 6964
MAP2K4 6866
NFKBIA 6807
PELI1 6715
BPI 6666
UBB 6639
TICAM2 6335
TICAM1 6307
NFKB1 6277
FBXW11 6196
MAP3K8 6160
IRAK1 6131
DNM2 6089
ATF1 5706
TAB1 5681
FADD 5641
TIRAP 5640
UBE2V1 5637
TNIP2 5552
FOS 5460
IKBKG 5377
PTPN11 5314
MAP3K1 5121
PLCG2 5006
ECSIT 4918
IKBKE 4715
BIRC2 4692
UBE2D2 4657
PPP2R1A 4589
UBC 4439
DUSP6 4357
MAPK10 4325
SKP1 4287
RIPK3 4217
MAPKAPK2 4054
SOCS1 3947
MAPK11 3826
JUN 3722
DNM1 3587
TBK1 3229
TAB3 3160
RPS6KA2 3087
RPS6KA3 2973
PPP2R5D 2421
MAP3K7 2395
ATF2 2085
UBE2N 1936
MAP2K7 1654
AGER 1294
VRK3 1281
UBA52 1121
ELK1 1040
RIPK2 1025
NKIRAS1 375
NFKBIB -152
TRAF6 -229
PPP2R1B -241
HMGB1 -252
MEF2C -293
CD180 -600
NFKB2 -1165
MAPK7 -1337
CREB1 -1378
RELA -1803
DUSP7 -3211
BTRC -4924
IKBKB -5386
S100B -5457
TRAF3 -5576
DUSP4 -6287
RPS27A -6938
MAPK9 -7068
IRF3 -8517
IRF7 -8657
MAPK8 -9428
IRAK2 -9548
SIGIRR -10752
RIPK1 -11074
BIRC3 -11125
CUL1 -11330
CASP8 -11336
RPS6KA5 -11594
SARM1 -12134
PTPN4 -12220
NOD1 -12263


rRNA processing

rRNA processing
1354
set rRNA processing
setSize 219
pANOVA 2.4e-13
s.dist -0.287
p.adjustANOVA 1.49e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
LAS1L -12267
NAT10 -11952
ELAC2 -11761
NOP56 -11750
RBM28 -11671
BMS1 -11670
DKC1 -11637
PDCD11 -11518
UTP4 -11494
EXOSC8 -11456
EXOSC10 -11379
TFB1M -11344
DDX47 -11299
EXOSC2 -11072
IMP4 -10976
WDR46 -10970
PELP1 -10928
NOL6 -10908
MTERF4 -10891
NOP14 -10866

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
LAS1L -12267
NAT10 -11952
ELAC2 -11761
NOP56 -11750
RBM28 -11671
BMS1 -11670
DKC1 -11637
PDCD11 -11518
UTP4 -11494
EXOSC8 -11456
EXOSC10 -11379
TFB1M -11344
DDX47 -11299
EXOSC2 -11072
IMP4 -10976
WDR46 -10970
PELP1 -10928
NOL6 -10908
MTERF4 -10891
NOP14 -10866
EXOSC7 -10631
UTP15 -10603
UTP20 -10529
MRM1 -10517
NOL11 -10471
HEATR1 -10345
NOB1 -10320
CSNK1E -10298
EXOSC9 -10250
NOL9 -10224
EMG1 -10189
FBL -10188
RRP9 -10080
NOP2 -9952
NOP58 -9951
WDR75 -9921
EXOSC6 -9839
THUMPD1 -9802
TEX10 -9765
RPS27 -9756
TSR1 -9731
RPL23A -9567
IMP3 -9459
NCL -9269
RPS20 -8886
RPL39L -8805
KRR1 -8623
RPL3 -8561
GNL3 -8489
DHX37 -8267
RPP25 -8247
RPL13A -8212
RPP30 -8101
RPL35 -8092
DIMT1 -7988
RPS29 -7940
MPHOSPH10 -7790
RPS18 -7744
WDR43 -7687
MRM3 -7522
RPL36A -7376
RPS11 -7243
MT-TL2 -7170
RPLP2 -7087
RPP38 -7076
RPL12 -7053
RPL30 -7020
RPS19 -6965
GAR1 -6941
RPS27A -6938
SNU13 -6871
RPL41 -6866
PNO1 -6861
RPL34 -6802
RPL14 -6710
RPL32 -6709
RPL10A -6686
WDR3 -6619
RPL26 -6612
MT-ND2 -6560
RPL10 -6534
RPL21 -6458
RPL37 -6375
RPS25 -6365
RPSA -6323
RPS23 -6292
RPS4X -6285
RPL19 -6281
RPL11 -6261
RPL27A -6257
RPS17 -6247
RPS6 -6160
RPL18A -6070
RPL35A -6015
RPS12 -5987
RPS3 -5914
NIP7 -5876
RPL38 -5840
RPL24 -5799
RPS10 -5793
RPS15A -5742
RPS5 -5691
DCAF13 -5572
NOC4L -5483
RPS14 -5463
RPL17 -5431
RPP21 -5355
RPL36 -5287
BOP1 -5212
RPL18 -5080
RPS7 -4968
RPP40 -4835
NSUN4 -4799
RPL22 -4740
RPL5 -4728
RPS28 -4713
RPS3A -4694
RPS16 -4669
EXOSC5 -4577
RPL31 -4541
UTP6 -4507
RPS2 -4499
TRMT10C -4481
BYSL -4461
DIS3 -4322
LTV1 -4296
EBNA1BP2 -4097
RPS21 -4079
FTSJ3 -4022
RPL37A -3946
WDR36 -3945
RIOK1 -3814
RPS15 -3673
RPL7A -3665
MT-TV -3652
MT-ND3 -3649
MT-ND1 -3616
RPL29 -3611
RPL4 -3582
NHP2 -3471
TBL3 -3437
RPL13 -3431
RPL6 -3354
RPL23 -3314
RRP1 -3084
MT-ATP8 -3067
RPL39 -3006
MT-TL1 -2976
UTP3 -2903
RPL27 -2855
RRP7A -2806
MT-TF -2754
MTREX -2638
SNORD3A -2539
WDR18 -2310
MT-CYB -2254
MT-ND5 -2166
MT-ATP6 -2096
RPS8 -2083
UTP14C -2073
PES1 -2033
MT-ND4L -2023
RPL7 -1955
RPL9 -1872
UTP14A -1821
RPS13 -1749
RRP36 -1672
RPL22L1 -1619
MT-TM -1516
RPL28 -1462
RPS26 -1430
PWP2 -1207
RPL8 -1187
RPLP0 -1000
EXOSC1 -991
RPL15 -963
RCL1 -757
FAU -362
MT-RNR1 -300
RPS24 -263
RPLP1 19
RPL36AL 32
MT-CO3 40
MT-CO2 48
RPS4Y1 424
DDX52 454
EXOSC3 509
MT-CO1 684
TRMT112 738
MT-ND4 840
RIOK2 934
UBA52 1121
MRM2 1460
RPS27L 2061
MT-RNR2 2112
MPHOSPH6 2181
CSNK1D 2390
SENP3 2994
RPP14 3005
DDX21 3113
PRORP 3390
C1D 3516
ISG20L2 3775
TSR3 3846
HSD17B10 4182
FCF1 4472
RPL3L 4503
UTP11 4631
DDX49 4872
NOL12 4944
UTP18 5114
WDR12 5217
RPS9 5421
ERI1 5541
RPL26L1 7176
EXOSC4 7600
NOP10 8332
RIOK3 8765
XRN2 9400


ER to Golgi Anterograde Transport

ER to Golgi Anterograde Transport
327
set ER to Golgi Anterograde Transport
setSize 129
pANOVA 2.87e-13
s.dist 0.372
p.adjustANOVA 1.53e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
F5 9485
ARF4 9191
SERPINA1 9168
DCTN2 9157
SPTB 9154
CD55 9145
KDELR1 9142
ARF1 9064
RAB1A 9052
CTSZ 8975
TGFA 8889
NSF 8829
ANK1 8771
CAPZA2 8597
DCTN4 8387
COPA 8366
RAB1B 8313
CAPZA1 8135
SEC24D 8115
CAPZB 8015

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
F5 9485
ARF4 9191
SERPINA1 9168
DCTN2 9157
SPTB 9154
CD55 9145
KDELR1 9142
ARF1 9064
RAB1A 9052
CTSZ 8975
TGFA 8889
NSF 8829
ANK1 8771
CAPZA2 8597
DCTN4 8387
COPA 8366
RAB1B 8313
CAPZA1 8135
SEC24D 8115
CAPZB 8015
TMED7 7950
COPB2 7902
ARF5 7885
TRAPPC1 7806
CNIH1 7779
DYNC1I2 7735
ARF3 7732
KDELR2 7728
SEC24A 7660
ACTR10 7605
SPTA1 7595
COPG2 7594
COPG1 7509
SEC23A 7335
COPB1 7321
DCTN6 7300
TMED9 7167
STX5 7166
TFG 7160
TRAPPC3 7114
MCFD2 7099
LMAN2 7080
F8 7022
ACTR1A 7002
DYNC1LI1 6941
LMAN2L 6937
COPE 6896
PPP6C 6819
GORASP1 6606
SAR1B 6479
PREB 6368
COL7A1 6304
GOLGA2 6203
TMED2 6052
DCTN3 5994
AREG 5977
DYNLL1 5952
SEC22B 5873
CD59 5859
SEC13 5748
ARCN1 5580
MIA2 5574
TMEM115 5508
TRAPPC9 5333
PPP6R1 5263
YKT6 5205
TRAPPC5 5191
DCTN1 5078
SEC16A 4619
DYNC1LI2 4273
COG7 4269
DYNC1I1 4187
USO1 4154
TRAPPC6B 4147
NAPG 4139
COPZ1 4035
ARFGAP3 3714
SEC24B 3608
SCFD1 3525
PPP6R3 3261
TMED3 2720
CSNK1D 2390
CTSC 2326
NAPA 1432
SEC31A 1099
CNIH2 654
SEC16B 330
TMED10 323
COG4 -6
TBC1D20 -18
GOSR1 -182
COG8 -346
SEC23IP -468
BET1 -594
GOSR2 -1456
ARFGAP1 -1942
KDELR3 -2117
TRAPPC2L -2299
SEC24C -2569
NAPB -2780
COG5 -3259
SPTBN5 -3531
DYNLL2 -3980
DCTN5 -4086
SEC22C -4248
GBF1 -4290
ANK3 -4919
SEC22A -5052
SPTBN2 -5129
GOLGB1 -5370
COG3 -5426
ARFGAP2 -5786
COG6 -5811
MIA3 -6245
ANKRD28 -6250
TRAPPC4 -6712
BET1L -7405
DYNC1H1 -7685
SPTBN1 -7764
COG2 -7917
TRAPPC2 -8704
CNIH3 -9011
TRAPPC10 -9369
LMAN1 -10630
COPZ2 -10863
TRAPPC6A -10917
STX17 -11006
SPTAN1 -11426
COG1 -12125


MyD88:MAL(TIRAP) cascade initiated on plasma membrane

MyD88:MAL(TIRAP) cascade initiated on plasma membrane
689
set MyD88:MAL(TIRAP) cascade initiated on plasma membrane
setSize 92
pANOVA 3.03e-13
s.dist 0.44
p.adjustANOVA 1.53e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A12 9515
CD36 9444
NKIRAS2 9353
DUSP3 9280
APP 9177
IRAK3 9107
MAPK14 9104
TLR2 9103
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
TLR1 8932
MAP2K6 8887
TLR6 8840
LY96 8795
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A12 9515
CD36 9444
NKIRAS2 9353
DUSP3 9280
APP 9177
IRAK3 9107
MAPK14 9104
TLR2 9103
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
TLR1 8932
MAP2K6 8887
TLR6 8840
LY96 8795
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966
PELI3 7716
PPP2CB 7712
RPS6KA1 7695
MAPK1 7493
BTK 7206
TAB2 6964
MAP2K4 6866
NFKBIA 6807
PELI1 6715
UBB 6639
NFKB1 6277
FBXW11 6196
MAP3K8 6160
IRAK1 6131
ATF1 5706
TAB1 5681
TIRAP 5640
UBE2V1 5637
TNIP2 5552
FOS 5460
IKBKG 5377
MAP3K1 5121
ECSIT 4918
PPP2R1A 4589
UBC 4439
DUSP6 4357
MAPK10 4325
SKP1 4287
MAPKAPK2 4054
SOCS1 3947
MAPK11 3826
JUN 3722
TAB3 3160
RPS6KA2 3087
RPS6KA3 2973
PPP2R5D 2421
MAP3K7 2395
ATF2 2085
UBE2N 1936
MAP2K7 1654
AGER 1294
VRK3 1281
UBA52 1121
ELK1 1040
RIPK2 1025
NKIRAS1 375
NFKBIB -152
TRAF6 -229
PPP2R1B -241
HMGB1 -252
MEF2C -293
NFKB2 -1165
MAPK7 -1337
CREB1 -1378
RELA -1803
DUSP7 -3211
BTRC -4924
IKBKB -5386
S100B -5457
DUSP4 -6287
RPS27A -6938
MAPK9 -7068
MAPK8 -9428
IRAK2 -9548
SIGIRR -10752
CUL1 -11330
RPS6KA5 -11594
NOD1 -12263


Toll Like Receptor 2 (TLR2) Cascade

Toll Like Receptor 2 (TLR2) Cascade
1237
set Toll Like Receptor 2 (TLR2) Cascade
setSize 92
pANOVA 3.03e-13
s.dist 0.44
p.adjustANOVA 1.53e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A12 9515
CD36 9444
NKIRAS2 9353
DUSP3 9280
APP 9177
IRAK3 9107
MAPK14 9104
TLR2 9103
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
TLR1 8932
MAP2K6 8887
TLR6 8840
LY96 8795
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A12 9515
CD36 9444
NKIRAS2 9353
DUSP3 9280
APP 9177
IRAK3 9107
MAPK14 9104
TLR2 9103
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
TLR1 8932
MAP2K6 8887
TLR6 8840
LY96 8795
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966
PELI3 7716
PPP2CB 7712
RPS6KA1 7695
MAPK1 7493
BTK 7206
TAB2 6964
MAP2K4 6866
NFKBIA 6807
PELI1 6715
UBB 6639
NFKB1 6277
FBXW11 6196
MAP3K8 6160
IRAK1 6131
ATF1 5706
TAB1 5681
TIRAP 5640
UBE2V1 5637
TNIP2 5552
FOS 5460
IKBKG 5377
MAP3K1 5121
ECSIT 4918
PPP2R1A 4589
UBC 4439
DUSP6 4357
MAPK10 4325
SKP1 4287
MAPKAPK2 4054
SOCS1 3947
MAPK11 3826
JUN 3722
TAB3 3160
RPS6KA2 3087
RPS6KA3 2973
PPP2R5D 2421
MAP3K7 2395
ATF2 2085
UBE2N 1936
MAP2K7 1654
AGER 1294
VRK3 1281
UBA52 1121
ELK1 1040
RIPK2 1025
NKIRAS1 375
NFKBIB -152
TRAF6 -229
PPP2R1B -241
HMGB1 -252
MEF2C -293
NFKB2 -1165
MAPK7 -1337
CREB1 -1378
RELA -1803
DUSP7 -3211
BTRC -4924
IKBKB -5386
S100B -5457
DUSP4 -6287
RPS27A -6938
MAPK9 -7068
MAPK8 -9428
IRAK2 -9548
SIGIRR -10752
CUL1 -11330
RPS6KA5 -11594
NOD1 -12263


Toll Like Receptor TLR1:TLR2 Cascade

Toll Like Receptor TLR1:TLR2 Cascade
1243
set Toll Like Receptor TLR1:TLR2 Cascade
setSize 92
pANOVA 3.03e-13
s.dist 0.44
p.adjustANOVA 1.53e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A12 9515
CD36 9444
NKIRAS2 9353
DUSP3 9280
APP 9177
IRAK3 9107
MAPK14 9104
TLR2 9103
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
TLR1 8932
MAP2K6 8887
TLR6 8840
LY96 8795
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A12 9515
CD36 9444
NKIRAS2 9353
DUSP3 9280
APP 9177
IRAK3 9107
MAPK14 9104
TLR2 9103
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
TLR1 8932
MAP2K6 8887
TLR6 8840
LY96 8795
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966
PELI3 7716
PPP2CB 7712
RPS6KA1 7695
MAPK1 7493
BTK 7206
TAB2 6964
MAP2K4 6866
NFKBIA 6807
PELI1 6715
UBB 6639
NFKB1 6277
FBXW11 6196
MAP3K8 6160
IRAK1 6131
ATF1 5706
TAB1 5681
TIRAP 5640
UBE2V1 5637
TNIP2 5552
FOS 5460
IKBKG 5377
MAP3K1 5121
ECSIT 4918
PPP2R1A 4589
UBC 4439
DUSP6 4357
MAPK10 4325
SKP1 4287
MAPKAPK2 4054
SOCS1 3947
MAPK11 3826
JUN 3722
TAB3 3160
RPS6KA2 3087
RPS6KA3 2973
PPP2R5D 2421
MAP3K7 2395
ATF2 2085
UBE2N 1936
MAP2K7 1654
AGER 1294
VRK3 1281
UBA52 1121
ELK1 1040
RIPK2 1025
NKIRAS1 375
NFKBIB -152
TRAF6 -229
PPP2R1B -241
HMGB1 -252
MEF2C -293
NFKB2 -1165
MAPK7 -1337
CREB1 -1378
RELA -1803
DUSP7 -3211
BTRC -4924
IKBKB -5386
S100B -5457
DUSP4 -6287
RPS27A -6938
MAPK9 -7068
MAPK8 -9428
IRAK2 -9548
SIGIRR -10752
CUL1 -11330
RPS6KA5 -11594
NOD1 -12263


Toll Like Receptor TLR6:TLR2 Cascade

Toll Like Receptor TLR6:TLR2 Cascade
1244
set Toll Like Receptor TLR6:TLR2 Cascade
setSize 92
pANOVA 3.03e-13
s.dist 0.44
p.adjustANOVA 1.53e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A12 9515
CD36 9444
NKIRAS2 9353
DUSP3 9280
APP 9177
IRAK3 9107
MAPK14 9104
TLR2 9103
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
TLR1 8932
MAP2K6 8887
TLR6 8840
LY96 8795
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A12 9515
CD36 9444
NKIRAS2 9353
DUSP3 9280
APP 9177
IRAK3 9107
MAPK14 9104
TLR2 9103
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
TLR1 8932
MAP2K6 8887
TLR6 8840
LY96 8795
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966
PELI3 7716
PPP2CB 7712
RPS6KA1 7695
MAPK1 7493
BTK 7206
TAB2 6964
MAP2K4 6866
NFKBIA 6807
PELI1 6715
UBB 6639
NFKB1 6277
FBXW11 6196
MAP3K8 6160
IRAK1 6131
ATF1 5706
TAB1 5681
TIRAP 5640
UBE2V1 5637
TNIP2 5552
FOS 5460
IKBKG 5377
MAP3K1 5121
ECSIT 4918
PPP2R1A 4589
UBC 4439
DUSP6 4357
MAPK10 4325
SKP1 4287
MAPKAPK2 4054
SOCS1 3947
MAPK11 3826
JUN 3722
TAB3 3160
RPS6KA2 3087
RPS6KA3 2973
PPP2R5D 2421
MAP3K7 2395
ATF2 2085
UBE2N 1936
MAP2K7 1654
AGER 1294
VRK3 1281
UBA52 1121
ELK1 1040
RIPK2 1025
NKIRAS1 375
NFKBIB -152
TRAF6 -229
PPP2R1B -241
HMGB1 -252
MEF2C -293
NFKB2 -1165
MAPK7 -1337
CREB1 -1378
RELA -1803
DUSP7 -3211
BTRC -4924
IKBKB -5386
S100B -5457
DUSP4 -6287
RPS27A -6938
MAPK9 -7068
MAPK8 -9428
IRAK2 -9548
SIGIRR -10752
CUL1 -11330
RPS6KA5 -11594
NOD1 -12263


rRNA processing in the nucleus and cytosol

rRNA processing in the nucleus and cytosol
1356
set rRNA processing in the nucleus and cytosol
setSize 190
pANOVA 3.58e-13
s.dist -0.306
p.adjustANOVA 1.75e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
LAS1L -12267
NAT10 -11952
NOP56 -11750
RBM28 -11671
BMS1 -11670
DKC1 -11637
PDCD11 -11518
UTP4 -11494
EXOSC8 -11456
EXOSC10 -11379
DDX47 -11299
EXOSC2 -11072
IMP4 -10976
WDR46 -10970
PELP1 -10928
NOL6 -10908
NOP14 -10866
EXOSC7 -10631
UTP15 -10603
UTP20 -10529

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
LAS1L -12267
NAT10 -11952
NOP56 -11750
RBM28 -11671
BMS1 -11670
DKC1 -11637
PDCD11 -11518
UTP4 -11494
EXOSC8 -11456
EXOSC10 -11379
DDX47 -11299
EXOSC2 -11072
IMP4 -10976
WDR46 -10970
PELP1 -10928
NOL6 -10908
NOP14 -10866
EXOSC7 -10631
UTP15 -10603
UTP20 -10529
NOL11 -10471
HEATR1 -10345
NOB1 -10320
CSNK1E -10298
EXOSC9 -10250
NOL9 -10224
EMG1 -10189
FBL -10188
RRP9 -10080
NOP2 -9952
NOP58 -9951
WDR75 -9921
EXOSC6 -9839
THUMPD1 -9802
TEX10 -9765
RPS27 -9756
TSR1 -9731
RPL23A -9567
IMP3 -9459
NCL -9269
RPS20 -8886
RPL39L -8805
KRR1 -8623
RPL3 -8561
GNL3 -8489
DHX37 -8267
RPP25 -8247
RPL13A -8212
RPP30 -8101
RPL35 -8092
DIMT1 -7988
RPS29 -7940
MPHOSPH10 -7790
RPS18 -7744
WDR43 -7687
RPL36A -7376
RPS11 -7243
RPLP2 -7087
RPP38 -7076
RPL12 -7053
RPL30 -7020
RPS19 -6965
GAR1 -6941
RPS27A -6938
SNU13 -6871
RPL41 -6866
PNO1 -6861
RPL34 -6802
RPL14 -6710
RPL32 -6709
RPL10A -6686
WDR3 -6619
RPL26 -6612
RPL10 -6534
RPL21 -6458
RPL37 -6375
RPS25 -6365
RPSA -6323
RPS23 -6292
RPS4X -6285
RPL19 -6281
RPL11 -6261
RPL27A -6257
RPS17 -6247
RPS6 -6160
RPL18A -6070
RPL35A -6015
RPS12 -5987
RPS3 -5914
NIP7 -5876
RPL38 -5840
RPL24 -5799
RPS10 -5793
RPS15A -5742
RPS5 -5691
DCAF13 -5572
NOC4L -5483
RPS14 -5463
RPL17 -5431
RPP21 -5355
RPL36 -5287
BOP1 -5212
RPL18 -5080
RPS7 -4968
RPP40 -4835
RPL22 -4740
RPL5 -4728
RPS28 -4713
RPS3A -4694
RPS16 -4669
EXOSC5 -4577
RPL31 -4541
UTP6 -4507
RPS2 -4499
BYSL -4461
DIS3 -4322
LTV1 -4296
EBNA1BP2 -4097
RPS21 -4079
FTSJ3 -4022
RPL37A -3946
WDR36 -3945
RIOK1 -3814
RPS15 -3673
RPL7A -3665
RPL29 -3611
RPL4 -3582
NHP2 -3471
TBL3 -3437
RPL13 -3431
RPL6 -3354
RPL23 -3314
RRP1 -3084
RPL39 -3006
UTP3 -2903
RPL27 -2855
RRP7A -2806
MTREX -2638
SNORD3A -2539
WDR18 -2310
RPS8 -2083
UTP14C -2073
PES1 -2033
RPL7 -1955
RPL9 -1872
UTP14A -1821
RPS13 -1749
RRP36 -1672
RPL22L1 -1619
RPL28 -1462
RPS26 -1430
PWP2 -1207
RPL8 -1187
RPLP0 -1000
EXOSC1 -991
RPL15 -963
RCL1 -757
FAU -362
RPS24 -263
RPLP1 19
RPL36AL 32
RPS4Y1 424
DDX52 454
EXOSC3 509
TRMT112 738
RIOK2 934
UBA52 1121
RPS27L 2061
MPHOSPH6 2181
CSNK1D 2390
SENP3 2994
RPP14 3005
DDX21 3113
C1D 3516
ISG20L2 3775
TSR3 3846
FCF1 4472
RPL3L 4503
UTP11 4631
DDX49 4872
NOL12 4944
UTP18 5114
WDR12 5217
RPS9 5421
ERI1 5541
RPL26L1 7176
EXOSC4 7600
NOP10 8332
RIOK3 8765
XRN2 9400


Signaling by NOTCH

Signaling by NOTCH
1108
set Signaling by NOTCH
setSize 183
pANOVA 3.84e-13
s.dist 0.311
p.adjustANOVA 1.81e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
NUMB 9414
H2AJ 9374
TACC3 9331
H2BC21 9283
NCSTN 9186
FURIN 9075
AGO4 9070
H2BC12 9051
HDAC4 8960
MAML3 8957
ADAM10 8791
RBPJ 8770
JAG1 8743
H3-3A 8661
TLE3 8558
ARRB2 8490
PSMB7 8485
TFDP1 8470
PSMD4 8402
PSME3 8251

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NUMB 9414.0
H2AJ 9374.0
TACC3 9331.0
H2BC21 9283.0
NCSTN 9186.0
FURIN 9075.0
AGO4 9070.0
H2BC12 9051.0
HDAC4 8960.0
MAML3 8957.0
ADAM10 8791.0
RBPJ 8770.0
JAG1 8743.0
H3-3A 8661.0
TLE3 8558.0
ARRB2 8490.0
PSMB7 8485.0
TFDP1 8470.0
PSMD4 8402.0
PSME3 8251.0
EGF 8179.0
RAB6A 8148.0
ADAM17 8110.0
PSMB5 8101.0
ATP2A2 8038.0
WWP2 8013.0
H2BC5 8003.0
NCOR2 7985.0
PSEN1 7961.0
H2AC6 7934.0
H2BC11 7912.0
NOTCH3 7899.0
TBL1X 7887.0
PSMD6 7846.0
PSMD9 7620.0
RUNX1 7529.0
PTCRA 7507.0
PLXND1 7475.0
HIF1A 7436.0
PSMD2 7411.0
H2BC4 7389.0
PSMA1 7329.0
H2BC17 7285.0
PSMD1 7241.0
RFNG 7233.0
PSMB3 7171.0
PSMA7 7096.0
PSMC1 7021.0
TLE4 6854.0
SEL1L 6847.0
PSMB6 6813.0
DTX2 6754.0
ST3GAL6 6701.0
H3C15 6699.5
PSMF1 6659.0
E2F3 6650.0
UBB 6639.0
PSMC6 6635.0
PSMD12 6556.0
E2F1 6343.0
APH1B 6280.0
PSMD11 6231.0
SIRT6 6214.0
DTX4 6156.0
EP300 6129.0
HDAC7 6122.0
TMED2 6052.0
H2AZ1 6036.0
PSMA6 5970.0
PSMD7 5963.0
PSMD13 5948.0
NCOR1 5887.0
ST3GAL4 5781.0
PSMD8 5757.0
PSENEN 5735.0
AGO1 5654.0
YWHAZ 5624.0
HDAC2 5482.0
MAML1 5404.0
H2BC9 5394.0
PSMA2 5339.0
H2BC15 5312.0
NOTCH2 5272.0
SNW1 5201.0
PBX1 5098.0
H2AC20 4972.0
HDAC11 4756.0
HDAC5 4710.0
NOTCH1 4704.0
HDAC3 4673.0
PSMD3 4618.0
TBL1XR1 4556.0
UBC 4439.0
SEM1 4348.0
B4GALT1 4292.0
SKP1 4287.0
APH1A 4133.0
PSMB2 4084.0
RBX1 3934.0
JUN 3722.0
AKT1 3614.0
PSMD5 3426.0
CREBBP 3423.0
PSMB1 3374.0
DLGAP5 3106.0
YBX1 3097.0
HDAC8 3079.0
AGO2 2995.0
PSMD14 2611.0
PSMC2 2598.0
PSMB4 2523.0
MYC 2304.0
HDAC10 2280.0
POFUT1 2056.0
ARRB1 1998.0
PSMC3 1976.0
CCNC 1877.0
PSMD10 1559.0
HDAC9 1359.0
ITCH 1318.0
WWC1 1180.0
UBA52 1121.0
ELF3 828.0
HDAC1 587.0
ST3GAL3 505.0
PRKCI -138.0
ACTA2 -429.0
MAML2 -582.0
PSMA4 -616.0
NBEA -703.0
PSMC5 -863.0
ATP2A3 -914.0
AGO3 -1011.0
H2AZ2 -1209.0
CREB1 -1378.0
CDK8 -1971.0
KAT2B -2414.0
NEURL1B -2586.0
MIB1 -2998.0
PSMB8 -3076.0
DTX1 -3340.0
MDK -3714.0
FCER2 -4230.0
TNRC6B -4518.0
ATP2A1 -4667.0
NOTCH4 -5229.0
PSMA3 -5285.0
MAMLD1 -5584.0
TNRC6A -5613.0
PSMB10 -5735.0
MFNG -6008.0
PSMA5 -6053.0
H2BU1 -6555.0
FBXW7 -6600.0
RPS27A -6938.0
TLE1 -6942.0
CCND1 -6970.0
FLT4 -7216.0
TLE2 -7449.0
IKZF1 -7704.0
PSEN2 -7718.0
HES1 -8266.0
HDAC6 -8337.0
LFNG -8372.0
POGLUT1 -9094.0
PSMC4 -9127.0
HEY2 -9752.0
PSME1 -9991.0
PSME2 -10336.0
KAT2A -10771.0
TP53 -10893.0
JAG2 -11044.0
MIB2 -11073.0
PSMB9 -11324.0
CUL1 -11330.0
NEURL1 -11633.0
STAT1 -11727.0
SMAD3 -11745.0
TNRC6C -11828.0
DLL1 -11885.0
MOV10 -11991.0
GZMB -12361.0
TFDP2 -12364.0


Interleukin-1 signaling

Interleukin-1 signaling
554
set Interleukin-1 signaling
setSize 98
pANOVA 5.37e-13
s.dist 0.422
p.adjustANOVA 2.44e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A12 9515
IL1RN 9381
NKIRAS2 9353
IL1R2 9188
APP 9177
IRAK3 9107
MAP2K1 9063
IL1R1 8917
MAP2K6 8887
TOLLIP 8572
PSMB7 8485
MAP3K3 8471
NOD2 8442
PSMD4 8402
PELI2 8314
PSME3 8251
MYD88 8136
PSMB5 8101
CHUK 7966
PSMD6 7846

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A12 9515
IL1RN 9381
NKIRAS2 9353
IL1R2 9188
APP 9177
IRAK3 9107
MAP2K1 9063
IL1R1 8917
MAP2K6 8887
TOLLIP 8572
PSMB7 8485
MAP3K3 8471
NOD2 8442
PSMD4 8402
PELI2 8314
PSME3 8251
MYD88 8136
PSMB5 8101
CHUK 7966
PSMD6 7846
PELI3 7716
PSMD9 7620
PSMD2 7411
PSMA1 7329
PSMD1 7241
PSMB3 7171
IL1RAP 7150
PSMA7 7096
PSMC1 7021
TAB2 6964
MAP2K4 6866
PSMB6 6813
NFKBIA 6807
PELI1 6715
PSMF1 6659
UBB 6639
PSMC6 6635
PSMD12 6556
NFKB1 6277
PSMD11 6231
FBXW11 6196
MAP3K8 6160
IRAK1 6131
PSMA6 5970
PSMD7 5963
PSMD13 5948
PSMD8 5757
TAB1 5681
UBE2V1 5637
TNIP2 5552
IKBKG 5377
PSMA2 5339
IL1B 4807
PSMD3 4618
UBC 4439
SEM1 4348
SKP1 4287
PSMB2 4084
SQSTM1 4081
RBX1 3934
PSMD5 3426
PSMB1 3374
TAB3 3160
PSMD14 2611
PSMC2 2598
PSMB4 2523
MAP3K7 2395
PSMC3 1976
UBE2N 1936
PSMD10 1559
AGER 1294
UBA52 1121
RIPK2 1025
NKIRAS1 375
NFKBIB -152
TRAF6 -229
HMGB1 -252
PSMA4 -616
PSMC5 -863
NFKB2 -1165
RELA -1803
PSMB8 -3076
BTRC -4924
PSMA3 -5285
IKBKB -5386
S100B -5457
PSMB10 -5735
PSMA5 -6053
PSME4 -6087
RPS27A -6938
PSMA8 -7606
PSMC4 -9127
IRAK2 -9548
PSME1 -9991
PSME2 -10336
PSMB9 -11324
CUL1 -11330
NOD1 -12263


Diseases of signal transduction by growth factor receptors and second messengers

Diseases of signal transduction by growth factor receptors and second messengers
298
set Diseases of signal transduction by growth factor receptors and second messengers
setSize 343
pANOVA 9.13e-13
s.dist 0.224
p.adjustANOVA 4.02e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
FZD5 9513
GRB2 9304
NCSTN 9186
KREMEN1 9149
MAP2K1 9063
FKBP1A 9056
PIK3CB 9038
PAPSS1 9003
QKI 8996
CUX1 8986
KL 8963
HDAC4 8960
MAML3 8957
AGTRAP 8956
MAPK3 8953
ERLIN2 8928
OS9 8898
ITGA2B 8893
TGFA 8889
HGF 8863

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FZD5 9513
GRB2 9304
NCSTN 9186
KREMEN1 9149
MAP2K1 9063
FKBP1A 9056
PIK3CB 9038
PAPSS1 9003
QKI 8996
CUX1 8986
KL 8963
HDAC4 8960
MAML3 8957
AGTRAP 8956
MAPK3 8953
ERLIN2 8928
OS9 8898
ITGA2B 8893
TGFA 8889
HGF 8863
RAC1 8793
ADAM10 8791
RBPJ 8770
APBB1IP 8744
JAG1 8743
MARK3 8697
FOXO3 8682
IRS2 8569
TLN1 8525
ARRB2 8490
RHOG 8487
PSMB7 8485
PTEN 8460
PSMD4 8402
AP3B1 8365
BAG4 8328
ITGB3 8291
FN1 8284
PSME3 8251
PPP2CA 8234
EGF 8179
IQGAP1 8152
PTPN12 8151
ATG7 8134
ADAM17 8110
PSMB5 8101
GAB2 8099
STAT3 8098
NCOR2 7985
CHUK 7966
PSEN1 7961
VAV1 7896
TBL1X 7887
RAF1 7879
AKT1S1 7865
PSMD6 7846
FGFR1OP2 7834
PIK3AP1 7811
LYN 7809
CSNK1A1 7766
GSK3A 7760
PPP2CB 7712
CASP9 7685
MAP3K11 7626
PSMD9 7620
POLR2E 7563
MAPK1 7493
CBL 7480
PSMD2 7411
BCL2L11 7384
SHOC2 7333
PSMA1 7329
VCL 7328
RAP1A 7305
PSMD1 7241
PSMB3 7171
PSMA7 7096
PPP1CB 7064
PSMC1 7021
STAT5A 6965
SPRED2 6936
STAT5B 6925
BAD 6892
VCP 6886
KDM7A 6855
SEL1L 6847
PSMB6 6813
MAP2K2 6794
PPP2R5B 6774
POLR2J 6671
PSMF1 6659
VWF 6641
UBB 6639
PSMC6 6635
GSK3B 6634
PSMD12 6556
CTNNB1 6408
FOXO4 6391
YWHAB 6385
PPP1CC 6330
LRRFIP1 6302
APH1B 6280
PSMD11 6231
AGGF1 6191
PDPK1 6136
EP300 6129
HDAC7 6122
PIK3CD 6046
AREG 5977
PSMA6 5970
PSMD7 5963
PSMD13 5948
PPP2R5A 5897
NCOR1 5887
PDGFRA 5858
PSMD8 5757
BIN2 5745
PSENEN 5735
GAB1 5679
HDAC2 5482
ETV6 5443
GTF2F2 5434
MAML1 5404
BRAP 5387
NRAS 5363
PSMA2 5339
PTPN11 5314
FXR1 5308
POLR2L 5305
PDGFA 5293
CSK 5219
SNW1 5201
RAC2 5163
TGFB1 5153
MAPKAP1 5057
TRAK1 5022
HBEGF 5013
PIK3R2 5010
FAM114A2 4963
GTF2F1 4951
SMAD2 4905
HDAC11 4756
HDAC5 4710
NOTCH1 4704
HDAC3 4673
PIK3CA 4629
PSMD3 4618
POLR2F 4604
PPP2R1A 4589
TBL1XR1 4556
CDKN1A 4511
UBC 4439
DUSP6 4357
SEM1 4348
MDM2 4312
LRP5 4289
SKP1 4287
KSR1 4167
SHC1 4161
APH1A 4133
CDC37 4096
PSMB2 4084
CTBP2 4080
RBX1 3934
FGF2 3920
TGFBR2 3914
LMNA 3887
SND1 3849
TRIM24 3806
NRG1 3750
KRAS 3702
STRN 3695
KIAA1549 3618
AKT1 3614
POLR2G 3508
PSMD5 3426
CREBBP 3423
PSMB1 3374
ZMYM2 3368
APC 3240
RAP1B 3206
HDAC8 3079
DERL2 3041
NF1 3036
JAK2 2691
EPGN 2662
ARAF 2644
PSMD14 2611
PSMC2 2598
PSMB4 2523
PPP2R5D 2421
MYC 2304
HDAC10 2280
CLCN6 2232
ARRB1 1998
PSMC3 1976
CAMK2G 1921
EREG 1888
CCNC 1877
IRS1 1741
POLR2C 1616
TGFBR1 1585
PSMD10 1559
HDAC9 1359
HSP90AA1 1326
BRAF 1308
UBA52 1121
SYVN1 992
RPS6KB2 700
ERLEC1 698
HDAC1 587
LRP6 577
AKT2 433
POLR2I 396
MLST8 376
KREMEN2 316
CD86 -14
PPP2R1B -241
ERBB3 -472
TNKS2 -499
ERBIN -574
MAML2 -582
PSMA4 -616
PPP2R5E -680
FAM131B -734
TSC2 -804
PSMC5 -863
CREB1 -1378
DUSP10 -1650
POLR2K -1783
NRG4 -1875
CDK8 -1971
CALM1 -2081
KAT2B -2414
POLR2B -2523
NEURL1B -2586
POLR2H -2942
PHB -2995
MIB1 -2998
PSMB8 -3076
POLR2A -3092
DUSP7 -3211
FGFR4 -3293
KSR2 -3361
HRAS -3382
FRS2 -3433
CD19 -3843
KANK1 -3964
MYO18A -3970
POLR2D -4024
GOLGA4 -4064
FGF7 -4247
CNKSR2 -4781
AKAP9 -5020
PSMA3 -5285
FGFR1 -5352
MAMLD1 -5584
SOS1 -5700
PSMB10 -5735
NCBP1 -5853
PSMA5 -6053
PSME4 -6087
CPSF6 -6137
MRAS -6172
TCF7L2 -6185
FOXO6 -6367
CTBP1 -6456
FZD6 -6525
FBXW7 -6600
FGF23 -6622
CNTRL -6639
DUSP16 -6655
NR4A1 -6756
FGFR1OP -6758
SPRED3 -6835
CD80 -6841
RPS27A -6938
BCR -7071
CNKSR1 -7089
FZD8 -7138
TRAT1 -7535
PSMA8 -7606
PSEN2 -7718
ZFYVE9 -7848
FIP1L1 -7928
CDKN1B -8207
HES1 -8266
HDAC6 -8337
SMAD4 -8351
PDGFB -8577
FGF22 -8607
SPRED1 -8639
TNKS -8738
FGF9 -8761
SRC -8820
ESR1 -9122
PSMC4 -9127
ESR2 -9250
HHAT -9301
ICOS -9434
FOXO1 -9465
PIK3R1 -9505
NCBP2 -9558
RICTOR -9670
HEY2 -9752
MTOR -9767
PSME1 -9991
ZC3HAV1 -10064
PORCN -10074
CD28 -10202
AXIN1 -10285
PSME2 -10336
KAT2A -10771
MPRIP -10959
KIT -11004
JAG2 -11044
MIB2 -11073
PLCG1 -11120
TENT4A -11168
PPP2R5C -11265
PEBP1 -11270
AMER1 -11301
PSMB9 -11324
CUL1 -11330
PDGFRB -11545
WDR48 -11565
NEURL1 -11633
DUSP8 -11639
FZD4 -11650
FYN -11675
STAT1 -11727
SMAD3 -11745
FGFR2 -11785
CAMK2D -11816
LCK -11838
AKT3 -11849
DLL1 -11885
PRR5 -11985
PIK3R3 -12015
AGK -12120
RNF43 -12121
YES1 -12142
ERBB2 -12320


Major pathway of rRNA processing in the nucleolus and cytosol

Major pathway of rRNA processing in the nucleolus and cytosol
626
set Major pathway of rRNA processing in the nucleolus and cytosol
setSize 180
pANOVA 1.68e-12
s.dist -0.305
p.adjustANOVA 7.17e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
LAS1L -12267
NOP56 -11750
RBM28 -11671
BMS1 -11670
PDCD11 -11518
UTP4 -11494
EXOSC8 -11456
EXOSC10 -11379
DDX47 -11299
EXOSC2 -11072
IMP4 -10976
WDR46 -10970
PELP1 -10928
NOL6 -10908
NOP14 -10866
EXOSC7 -10631
UTP15 -10603
UTP20 -10529
NOL11 -10471
HEATR1 -10345

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
LAS1L -12267
NOP56 -11750
RBM28 -11671
BMS1 -11670
PDCD11 -11518
UTP4 -11494
EXOSC8 -11456
EXOSC10 -11379
DDX47 -11299
EXOSC2 -11072
IMP4 -10976
WDR46 -10970
PELP1 -10928
NOL6 -10908
NOP14 -10866
EXOSC7 -10631
UTP15 -10603
UTP20 -10529
NOL11 -10471
HEATR1 -10345
NOB1 -10320
CSNK1E -10298
EXOSC9 -10250
NOL9 -10224
EMG1 -10189
FBL -10188
RRP9 -10080
NOP58 -9951
WDR75 -9921
EXOSC6 -9839
TEX10 -9765
RPS27 -9756
TSR1 -9731
RPL23A -9567
IMP3 -9459
NCL -9269
RPS20 -8886
RPL39L -8805
KRR1 -8623
RPL3 -8561
GNL3 -8489
DHX37 -8267
RPP25 -8247
RPL13A -8212
RPP30 -8101
RPL35 -8092
RPS29 -7940
MPHOSPH10 -7790
RPS18 -7744
WDR43 -7687
RPL36A -7376
RPS11 -7243
RPLP2 -7087
RPP38 -7076
RPL12 -7053
RPL30 -7020
RPS19 -6965
RPS27A -6938
SNU13 -6871
RPL41 -6866
PNO1 -6861
RPL34 -6802
RPL14 -6710
RPL32 -6709
RPL10A -6686
WDR3 -6619
RPL26 -6612
RPL10 -6534
RPL21 -6458
RPL37 -6375
RPS25 -6365
RPSA -6323
RPS23 -6292
RPS4X -6285
RPL19 -6281
RPL11 -6261
RPL27A -6257
RPS17 -6247
RPS6 -6160
RPL18A -6070
RPL35A -6015
RPS12 -5987
RPS3 -5914
NIP7 -5876
RPL38 -5840
RPL24 -5799
RPS10 -5793
RPS15A -5742
RPS5 -5691
DCAF13 -5572
NOC4L -5483
RPS14 -5463
RPL17 -5431
RPP21 -5355
RPL36 -5287
BOP1 -5212
RPL18 -5080
RPS7 -4968
RPP40 -4835
RPL22 -4740
RPL5 -4728
RPS28 -4713
RPS3A -4694
RPS16 -4669
EXOSC5 -4577
RPL31 -4541
UTP6 -4507
RPS2 -4499
BYSL -4461
DIS3 -4322
LTV1 -4296
EBNA1BP2 -4097
RPS21 -4079
FTSJ3 -4022
RPL37A -3946
WDR36 -3945
RIOK1 -3814
RPS15 -3673
RPL7A -3665
RPL29 -3611
RPL4 -3582
TBL3 -3437
RPL13 -3431
RPL6 -3354
RPL23 -3314
RRP1 -3084
RPL39 -3006
UTP3 -2903
RPL27 -2855
RRP7A -2806
MTREX -2638
SNORD3A -2539
WDR18 -2310
RPS8 -2083
UTP14C -2073
PES1 -2033
RPL7 -1955
RPL9 -1872
UTP14A -1821
RPS13 -1749
RRP36 -1672
RPL22L1 -1619
RPL28 -1462
RPS26 -1430
PWP2 -1207
RPL8 -1187
RPLP0 -1000
EXOSC1 -991
RPL15 -963
RCL1 -757
FAU -362
RPS24 -263
RPLP1 19
RPL36AL 32
RPS4Y1 424
DDX52 454
EXOSC3 509
RIOK2 934
UBA52 1121
RPS27L 2061
MPHOSPH6 2181
CSNK1D 2390
SENP3 2994
RPP14 3005
DDX21 3113
C1D 3516
ISG20L2 3775
FCF1 4472
RPL3L 4503
UTP11 4631
DDX49 4872
NOL12 4944
UTP18 5114
WDR12 5217
RPS9 5421
ERI1 5541
RPL26L1 7176
EXOSC4 7600
RIOK3 8765
XRN2 9400


Clathrin-mediated endocytosis

Clathrin-mediated endocytosis
191
set Clathrin-mediated endocytosis
setSize 127
pANOVA 3.15e-12
s.dist 0.358
p.adjustANOVA 1.3e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
VAMP7 9499
GRB2 9304
ITSN1 9289
AGFG1 9211
PICALM 9022
CLTC 9000
CLTCL1 8965
ARPC1A 8894
TGFA 8889
TGOLN2 8714
ARPC5 8686
RAB5C 8655
AP2M1 8627
FNBP1L 8551
AMPH 8532
ARRB2 8490
CLTA 8376
ARPC3 8277
HIP1 8258
VAMP3 8222

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
VAMP7 9499
GRB2 9304
ITSN1 9289
AGFG1 9211
PICALM 9022
CLTC 9000
CLTCL1 8965
ARPC1A 8894
TGFA 8889
TGOLN2 8714
ARPC5 8686
RAB5C 8655
AP2M1 8627
FNBP1L 8551
AMPH 8532
ARRB2 8490
CLTA 8376
ARPC3 8277
HIP1 8258
VAMP3 8222
EGF 8179
REPS2 8154
PACSIN2 8123
DAB2 8112
EPN1 8045
TOR1A 8033
AP2S1 8026
ACTR2 7870
ACTR3 7818
FCHO2 7807
SH3GL1 7625
ARPC4 7516
CBL 7480
ARPC2 7390
AP2A2 7257
IGF2R 7149
RAB5A 7103
DNM3 7045
SNX18 7017
AP2A1 6832
GAPVD1 6799
RAB5B 6690
UBB 6639
GRK3 6593
COPS7A 6590
NEDD8 6482
OCRL 6442
SYNJ1 6296
LDLR 6183
SH3KBP1 6173
STAM2 6159
COPS2 6139
DNM2 6089
CLTB 6084
GRK2 6068
COPS3 6005
AREG 5977
UBQLN2 5939
CTTN 5930
SCARB2 5255
VAMP8 5218
UBQLN1 5108
ITSN2 5060
SYT1 5056
HBEGF 5013
DNAJC6 4640
HGS 4513
UBC 4439
COPS5 4361
EPS15 4138
EPS15L1 3655
DNM1 3587
STON2 3569
PIP5K1C 3419
NECAP2 3387
VAMP4 3191
KIAA0319 3163
EPGN 2662
STON1 2574
GAK 2570
CFTR 2416
TRIP10 2343
NECAP1 2220
ARRB1 1998
EREG 1888
COPS4 1776
COPS6 1637
TFRC 1524
ARF6 1377
LRP2 1307
STAM 1285
UBA52 1121
TF 1102
SYT2 461
WASL 299
AVPR2 291
FNBP1 -311
SNX9 -430
ARFGAP1 -1942
TOR1B -2136
FCHO1 -2392
AP2B1 -2709
EPN2 -4100
GPS1 -4517
PIK3C2A -5194
CD4 -5406
SYT11 -6763
RPS27A -6938
REPS1 -7137
SYNJ2 -8511
M6PR -8519
COPS8 -8755
AAK1 -9190
LDLRAP1 -9326
COPS7B -9775
IL7R -10546
HIP1R -10615
HSPA8 -10922
DVL2 -11152
CD3D -11401
BIN1 -11411
CD3G -11526
FZD4 -11650
SLC2A8 -11749
VAMP2 -11779
ADRB2 -11892
PACSIN1 -12374


Signaling by Rho GTPases

Signaling by Rho GTPases
1133
set Signaling by Rho GTPases
setSize 367
pANOVA 4.57e-12
s.dist 0.21
p.adjustANOVA 1.83e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
WASF1 9520
S100A9 9516
S100A8 9503
H2AJ 9374
RHOT1 9367
CTNNA1 9341
ARHGEF11 9305
GRB2 9304
ITSN1 9289
H2BC21 9283
NCF4 9268
CYFIP1 9265
YWHAG 9264
ARPC1B 9259
NCF2 9190
MAPK14 9104
H2BC12 9051
YWHAE 9045
CYBB 9031
ACTB 9011

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
WASF1 9520.0
S100A9 9516.0
S100A8 9503.0
H2AJ 9374.0
RHOT1 9367.0
CTNNA1 9341.0
ARHGEF11 9305.0
GRB2 9304.0
ITSN1 9289.0
H2BC21 9283.0
NCF4 9268.0
CYFIP1 9265.0
YWHAG 9264.0
ARPC1B 9259.0
NCF2 9190.0
MAPK14 9104.0
H2BC12 9051.0
YWHAE 9045.0
CYBB 9031.0
ACTB 9011.0
PRKCD 9008.0
DLG4 9007.0
MAPK3 8953.0
FGD4 8948.0
ARPC1A 8894.0
ARHGAP18 8852.0
RHOU 8794.0
RAC1 8793.0
ARHGEF40 8723.0
ARPC5 8686.0
H3-3A 8661.0
YWHAH 8649.0
ARHGDIB 8639.0
MYL6 8576.0
ACTG1 8562.0
WAS 8560.0
CLIP1 8540.0
DIAPH2 8523.0
DLC1 8488.0
RHOG 8487.0
WASF2 8369.0
ARHGAP26 8368.0
MRTFA 8350.0
RHOA 8319.0
SOS2 8299.0
ARPC3 8277.0
TAX1BP3 8262.0
KIF5B 8239.0
PPP2CA 8234.0
PAK1 8230.0
ARAP3 8225.0
CFL1 8186.0
PAK2 8185.0
B9D2 8168.0
IQGAP1 8152.0
ARHGAP29 8084.0
LIMK2 8074.0
H2BC5 8003.0
RHOBTB1 7943.0
H2AC6 7934.0
H2BC11 7912.0
VAV1 7896.0
ACTR2 7870.0
GMIP 7856.0
ACTR3 7818.0
ARAP1 7817.0
ARHGAP19 7756.0
DYNC1I2 7735.0
PPP2CB 7712.0
MYL9 7703.0
NCKAP1L 7673.0
MAPRE1 7658.0
NDEL1 7627.0
CDC42 7537.0
ARHGAP24 7523.0
ARPC4 7516.0
RHOQ 7511.0
MAPK1 7493.0
ROCK1 7489.0
NCKAP1 7462.0
ARHGAP6 7433.0
PLEKHG2 7395.0
FAM13A 7392.0
ARPC2 7390.0
H2BC4 7389.0
KLC3 7377.0
NCF1 7334.0
H2BC17 7285.0
GDI2 7282.0
BTK 7206.0
PRKCB 7097.0
ABI1 7082.0
SRF 7079.0
PPP1CB 7064.0
BRK1 7032.0
DYNC1LI1 6941.0
CYBA 6922.0
ARHGEF17 6852.0
PPP1R14A 6839.0
WASF3 6808.0
RALBP1 6796.0
PPP2R5B 6774.0
SRGAP1 6744.0
H3C15 6699.5
MYH9 6685.0
MYLK 6618.0
IQGAP2 6599.0
ARHGEF2 6546.0
OCRL 6442.0
MYO9B 6424.0
PREX1 6414.0
CTNNB1 6408.0
YWHAB 6385.0
PPP1CC 6330.0
ABR 6260.0
ARHGAP9 6256.0
SRGAP2 6171.0
ROCK2 6138.0
PDPK1 6136.0
ARHGDIA 6104.0
ARHGEF37 6100.0
PPP1R12A 6050.0
H2AZ1 6036.0
DYNLL1 5952.0
CTTN 5930.0
PPP2R5A 5897.0
GNA13 5836.0
ARHGAP27 5830.0
SEC13 5748.0
GDI1 5739.0
WIPF2 5713.0
DVL3 5656.0
YWHAZ 5624.0
ARHGAP23 5618.0
ECT2 5570.0
KLC1 5523.0
ARHGAP31 5501.0
PAFAH1B1 5470.0
PFN1 5459.0
TAOK1 5420.0
NSL1 5408.0
H2BC9 5394.0
H2BC15 5312.0
RAC2 5163.0
MYL12B 5088.0
ARHGAP30 5039.0
ARHGAP21 5032.0
PIK3R2 5010.0
H2AC20 4972.0
CDC25C 4969.0
CHN2 4938.0
VAV3 4894.0
AR 4840.0
LIMK1 4679.0
ARHGAP1 4613.0
PPP2R1A 4589.0
FGD2 4576.0
PTK2 4462.0
DIAPH3 4379.0
DYNC1LI2 4273.0
DYNC1I1 4187.0
CENPA 4162.0
FMNL1 4150.0
CDC20 3998.0
STARD8 3913.0
MAPK11 3826.0
BIRC5 3738.0
DAAM1 3466.0
FGD3 3408.0
AKAP13 3393.0
IQGAP3 3370.0
PMF1 3364.0
KTN1 3363.0
BUB1 3362.0
KIF14 3352.0
ARHGEF12 3166.0
NUP98 3101.0
STARD13 3078.0
NUP37 3074.0
KLK2 3029.0
PLK1 3002.0
BUB1B 2997.0
RACGAP1 2848.0
ARHGAP28 2835.0
CENPF 2723.0
SKA1 2649.0
ARHGAP32 2642.0
NDE1 2594.0
ARHGEF6 2453.0
PPP2R5D 2421.0
CFTR 2416.0
TRIP10 2343.0
SPC24 2306.0
MCF2 2018.0
TRIO 1820.0
PPP1R12B 1775.0
DEPDC1B 1774.0
ARHGAP11A 1642.0
PIK3C3 1619.0
SFN 1615.0
ARHGAP22 1595.0
RHOB 1254.0
ARHGAP4 1204.0
PRKCA 1132.0
NCOA2 1092.0
PRC1 980.0
AURKB 846.0
KIF2C 726.0
DEPDC7 725.0
MYH10 653.0
TIAM1 651.0
WIPF1 569.0
FLNA 483.0
CENPE 332.0
NCKIPSD 328.0
WASL 299.0
ARHGAP15 272.0
ABL1 226.0
PKN2 98.0
ZW10 31.0
CENPN 20.0
DVL1 0.0
ITGB1 -94.0
BAIAP2 -215.0
PPP2R1B -241.0
ERCC6L -415.0
ARHGAP44 -483.0
KNL1 -581.0
CLASP1 -588.0
PPP2R5E -680.0
NUDC -709.0
RANBP2 -820.0
SYDE2 -845.0
DIAPH1 -854.0
KIF2A -1069.0
OPHN1 -1158.0
XPO1 -1185.0
H2AZ2 -1209.0
AHCTF1 -1644.0
CDCA8 -1838.0
CALM1 -2081.0
CLASP2 -2151.0
PKN1 -2208.0
PFN2 -2339.0
KIF18A -2742.0
NUP85 -3049.0
CENPI -3162.0
PIN1 -3188.0
RAC3 -3262.0
ARHGAP35 -3359.0
SGO2 -3480.0
MYH11 -3522.0
KALRN -3692.0
LIN7B -3725.0
PKN3 -3793.0
ARHGEF4 -3861.0
ARHGEF38 -3906.0
ARHGEF26 -3971.0
DYNLL2 -3980.0
ARHGEF10 -4015.0
VAV2 -4055.0
PIK3R4 -4062.0
PAK3 -4184.0
NUF2 -4301.0
FMNL2 -4424.0
ARHGEF35 -4533.0
ARHGEF7 -4583.0
RHPN2 -4650.0
ZWINT -4742.0
MAD1L1 -4981.0
CIT -5064.0
CENPO -5135.0
RCC2 -5148.0
RHPN1 -5327.0
CENPM -5376.0
NOXA1 -5464.0
ARHGAP33 -5517.0
RHOT2 -5546.0
RHOBTB2 -5551.0
ARHGEF1 -5559.0
SRGAP3 -5675.0
SOS1 -5700.0
INCENP -5956.0
SEH1L -6069.0
CKAP5 -6246.0
ARHGEF10L -6295.0
CENPQ -6366.0
NF2 -6540.0
H2BU1 -6555.0
CENPU -6692.0
SGO1 -6715.0
OBSCN -6727.0
ARHGEF18 -6799.0
ARHGEF5 -6944.0
INPP5B -7024.0
BCR -7071.0
YWHAQ -7340.0
NET1 -7419.0
ARHGAP12 -7547.0
ARHGAP42 -7608.0
ITGB3BP -7621.0
DYNC1H1 -7685.0
NUP133 -7762.0
ARHGAP11B -7789.0
CHN1 -7833.0
SCAI -7879.0
ARHGAP17 -7888.0
KNTC1 -7897.0
MAD2L1 -7944.0
ARHGAP39 -8166.0
CDKN1B -8207.0
CENPK -8334.0
KLC4 -8376.0
ARHGAP25 -8441.0
MEN1 -8538.0
MCF2L -8571.0
CENPH -8633.0
PLEKHG5 -8758.0
ARHGEF19 -8776.0
SRC -8820.0
ARHGAP10 -8847.0
KIF5A -8869.0
ARHGAP5 -8885.0
SKA2 -8999.0
KLC2 -9059.0
NDC80 -9165.0
KDM1A -9430.0
NUP43 -9517.0
MYO9A -9588.0
CENPT -9606.0
RPS27 -9756.0
GOPC -9831.0
A2M -9870.0
RASGRF2 -10175.0
CYFIP2 -10367.0
NUP107 -10421.0
FAM13B -10519.0
NUP160 -10557.0
RHOH -10626.0
KDM4C -10749.0
DSN1 -10773.0
ARHGEF39 -10833.0
MIS12 -10903.0
ABI2 -10915.0
TIAM2 -10979.0
DVL2 -11152.0
PPP2R5C -11265.0
RHOC -11360.0
NCK1 -11454.0
CDH1 -11500.0
SPDL1 -11534.0
PRKCZ -11629.0
BUB3 -11709.0
RANGAP1 -11722.0
ZWILCH -11724.0
CENPL -11782.0
CENPP -11814.0
CENPC -11888.0
ARAP2 -11984.0
ARHGEF3 -12022.0
FMNL3 -12087.0
EVL -12207.0
RTKN -12249.0
ARHGAP8 -12284.0
TAGAP -12285.0
ARHGEF9 -12299.0
RHOF -12344.0


Interleukin-1 family signaling

Interleukin-1 family signaling
553
set Interleukin-1 family signaling
setSize 125
pANOVA 8.55e-12
s.dist 0.353
p.adjustANOVA 3.33e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A12 9515
IL1RN 9381
NKIRAS2 9353
IL1R2 9188
APP 9177
IRAK3 9107
MAP2K1 9063
ALOX5 9001
IL1R1 8917
MAP2K6 8887
TOLLIP 8572
PSMB7 8485
MAP3K3 8471
NOD2 8442
PSMD4 8402
PELI2 8314
PSME3 8251
PTPN12 8151
MYD88 8136
PSMB5 8101

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A12 9515
IL1RN 9381
NKIRAS2 9353
IL1R2 9188
APP 9177
IRAK3 9107
MAP2K1 9063
ALOX5 9001
IL1R1 8917
MAP2K6 8887
TOLLIP 8572
PSMB7 8485
MAP3K3 8471
NOD2 8442
PSMD4 8402
PELI2 8314
PSME3 8251
PTPN12 8151
MYD88 8136
PSMB5 8101
STAT3 8098
CHUK 7966
PSMD6 7846
PELI3 7716
PSMD9 7620
PTPN2 7615
PSMD2 7411
IL18 7381
PSMA1 7329
PSMD1 7241
PSMB3 7171
IL1RAP 7150
PSMA7 7096
PSMC1 7021
TAB2 6964
MAP2K4 6866
PSMB6 6813
NFKBIA 6807
PELI1 6715
PTPN9 6712
PSMF1 6659
UBB 6639
PSMC6 6635
PSMD12 6556
NFKB1 6277
PSMD11 6231
FBXW11 6196
MAP3K8 6160
PTPN18 6149
IRAK1 6131
PTPN6 6096
PSMA6 5970
PSMD7 5963
PSMD13 5948
PSMD8 5757
TAB1 5681
UBE2V1 5637
TNIP2 5552
IKBKG 5377
PSMA2 5339
PTPN11 5314
CTSG 5115
IL1B 4807
PSMD3 4618
UBC 4439
SEM1 4348
SKP1 4287
CASP1 4224
PSMB2 4084
SQSTM1 4081
IL18R1 3994
RBX1 3934
PSMD5 3426
PSMB1 3374
TBK1 3229
IL1RL1 3175
TAB3 3160
PSMD14 2611
PSMC2 2598
PSMB4 2523
MAP3K7 2395
PSMC3 1976
UBE2N 1936
PSMD10 1559
AGER 1294
UBA52 1121
RIPK2 1025
IL18RAP 823
IL33 445
NKIRAS1 375
NFKBIB -152
TRAF6 -229
HMGB1 -252
PSMA4 -616
PSMC5 -863
NFKB2 -1165
PTPN23 -1186
RELA -1803
PTPN14 -2386
PSMB8 -3076
PTPN20 -3783
BTRC -4924
PSMA3 -5285
IKBKB -5386
S100B -5457
PSMB10 -5735
PSMA5 -6053
PSME4 -6087
RPS27A -6938
PSMA8 -7606
PSMC4 -9127
MAPK8 -9428
IRAK2 -9548
PTPN13 -9962
PSME1 -9991
PSME2 -10336
IL4 -10399
IL18BP -10561
SIGIRR -10752
PTPN7 -10868
PSMB9 -11324
CUL1 -11330
SMAD3 -11745
PTPN4 -12220
NOD1 -12263


Signaling by NTRKs

Signaling by NTRKs
1120
set Signaling by NTRKs
setSize 116
pANOVA 9.74e-12
s.dist 0.366
p.adjustANOVA 3.69e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
GRB2 9304
DUSP3 9280
RIT1 9121
MAPK14 9104
FURIN 9075
MAP2K1 9063
PIK3CB 9038
CLTC 9000
MAPK3 8953
CRK 8906
RAC1 8793
FOSL1 8788
PCSK6 8740
AP2M1 8627
CDK5 8616
IRS2 8569
RALB 8414
MAPKAPK3 8382
CLTA 8376
RHOA 8319

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GRB2 9304
DUSP3 9280
RIT1 9121
MAPK14 9104
FURIN 9075
MAP2K1 9063
PIK3CB 9038
CLTC 9000
MAPK3 8953
CRK 8906
RAC1 8793
FOSL1 8788
PCSK6 8740
AP2M1 8627
CDK5 8616
IRS2 8569
RALB 8414
MAPKAPK3 8382
CLTA 8376
RHOA 8319
PPP2CA 8234
LYL1 8221
STAT3 8098
AP2S1 8026
MEF2A 8009
PPP2CB 7712
RPS6KA1 7695
TRIB1 7643
MAPK1 7493
FRS3 7343
RAP1A 7305
AP2A2 7257
SRF 7079
KIDINS220 7069
DNM3 7045
AP2A1 6832
JUNB 6806
MAP2K2 6794
YWHAB 6385
EP300 6129
DNM2 6089
BAX 5916
ATF1 5706
GAB1 5679
FOS 5460
NRAS 5363
PTPN11 5314
PIK3R2 5010
ID1 4927
PCSK5 4863
PIK3CA 4629
SGK1 4595
PPP2R1A 4589
DUSP6 4357
SHC2 4183
SHC1 4161
MAPKAPK2 4054
SHC3 3974
CRKL 3966
MAP2K5 3940
MAPK13 3865
MAPK11 3826
KRAS 3702
DNM1 3587
DNAL4 3398
ADORA2A 3293
EGR1 3124
RPS6KA2 3087
NTRK3 3068
RPS6KA3 2973
RALA 2710
PTPRO 2501
PPP2R5D 2421
ATF2 2085
IRS1 1741
JUND 1549
FOSB 1368
NAB1 1342
BRAF 1308
VRK3 1281
TF 1102
ELK1 1040
REST 865
TIAM1 651
NELFB 374
EGR3 44
PPP2R1B -241
MEF2C -293
MAPK12 -1074
CDK5R1 -1089
TCF12 -1233
MAPK7 -1337
CREB1 -1378
EGR2 -1435
AP2B1 -2709
MEF2D -3094
DUSP7 -3211
HRAS -3382
FRS2 -3433
CHD4 -4515
DOCK3 -4640
SOS1 -5700
DUSP4 -6287
NTRK1 -8193
TPH1 -8640
SRC -8820
PIK3R1 -9505
ID3 -9614
RAPGEF1 -9826
NAB2 -10400
ID2 -10969
PLCG1 -11120
RPS6KA5 -11594
FYN -11675
RALGDS -12140
PTPRS -12291


TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation

TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
1213
set TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
setSize 88
pANOVA 1.49e-11
s.dist 0.416
p.adjustANOVA 5.49e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
TLR8 9343
DUSP3 9280
APP 9177
MAPK14 9104
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
MAP2K6 8887
LY96 8795
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
TLR8 9343
DUSP3 9280
APP 9177
MAPK14 9104
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
MAP2K6 8887
LY96 8795
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966
PELI3 7716
PPP2CB 7712
RPS6KA1 7695
MAPK1 7493
TAB2 6964
MAP2K4 6866
NFKBIA 6807
PELI1 6715
UBB 6639
TICAM2 6335
TICAM1 6307
NFKB1 6277
FBXW11 6196
MAP3K8 6160
IRAK1 6131
ATF1 5706
TAB1 5681
UBE2V1 5637
TNIP2 5552
FOS 5460
IKBKG 5377
MAP3K1 5121
ECSIT 4918
PPP2R1A 4589
UBC 4439
DUSP6 4357
MAPK10 4325
SKP1 4287
MAPKAPK2 4054
MAPK11 3826
JUN 3722
TAB3 3160
RPS6KA2 3087
RPS6KA3 2973
PPP2R5D 2421
MAP3K7 2395
ATF2 2085
UBE2N 1936
MAP2K7 1654
AGER 1294
VRK3 1281
UBA52 1121
ELK1 1040
RIPK2 1025
NKIRAS1 375
NFKBIB -152
TRAF6 -229
PPP2R1B -241
HMGB1 -252
MEF2C -293
TLR7 -625
NFKB2 -1165
MAPK7 -1337
CREB1 -1378
RELA -1803
DUSP7 -3211
BTRC -4924
IKBKB -5386
S100B -5457
TLR9 -5999
DUSP4 -6287
RPS27A -6938
MAPK9 -7068
MAPK8 -9428
IRAK2 -9548
CUL1 -11330
RPS6KA5 -11594
NOD1 -12263


Transport to the Golgi and subsequent modification

Transport to the Golgi and subsequent modification
1292
set Transport to the Golgi and subsequent modification
setSize 155
pANOVA 1.6e-11
s.dist 0.313
p.adjustANOVA 5.73e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
F5 9485
ARF4 9191
SERPINA1 9168
DCTN2 9157
SPTB 9154
CD55 9145
KDELR1 9142
ARF1 9064
RAB1A 9052
CTSZ 8975
TGFA 8889
B4GALT5 8830
NSF 8829
ANK1 8771
MGAT4B 8675
CAPZA2 8597
DCTN4 8387
COPA 8366
RAB1B 8313
CAPZA1 8135

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
F5 9485
ARF4 9191
SERPINA1 9168
DCTN2 9157
SPTB 9154
CD55 9145
KDELR1 9142
ARF1 9064
RAB1A 9052
CTSZ 8975
TGFA 8889
B4GALT5 8830
NSF 8829
ANK1 8771
MGAT4B 8675
CAPZA2 8597
DCTN4 8387
COPA 8366
RAB1B 8313
CAPZA1 8135
SEC24D 8115
CAPZB 8015
TMED7 7950
MAN1A1 7927
COPB2 7902
ARF5 7885
TRAPPC1 7806
CNIH1 7779
DYNC1I2 7735
ARF3 7732
KDELR2 7728
SEC24A 7660
ACTR10 7605
SPTA1 7595
COPG2 7594
COPG1 7509
FUCA1 7408
SEC23A 7335
COPB1 7321
DCTN6 7300
TMED9 7167
STX5 7166
TFG 7160
TRAPPC3 7114
MCFD2 7099
LMAN2 7080
F8 7022
ACTR1A 7002
DYNC1LI1 6941
LMAN2L 6937
COPE 6896
PPP6C 6819
MAN2A2 6625
GORASP1 6606
SAR1B 6479
PREB 6368
COL7A1 6304
MGAT1 6257
GOLGA2 6203
TMED2 6052
DCTN3 5994
AREG 5977
DYNLL1 5952
CHST8 5900
SEC22B 5873
CD59 5859
ST3GAL4 5781
SEC13 5748
ARCN1 5580
MIA2 5574
TMEM115 5508
TRAPPC9 5333
PPP6R1 5263
YKT6 5205
TRAPPC5 5191
DCTN1 5078
SEC16A 4619
B4GALT1 4292
DYNC1LI2 4273
COG7 4269
DYNC1I1 4187
USO1 4154
TRAPPC6B 4147
NAPG 4139
COPZ1 4035
ARFGAP3 3714
SEC24B 3608
SCFD1 3525
PPP6R3 3261
TMED3 2720
CSNK1D 2390
CTSC 2326
MGAT2 1633
NAPA 1432
SEC31A 1099
CNIH2 654
B4GALT4 391
SEC16B 330
TMED10 323
COG4 -6
TBC1D20 -18
GOSR1 -182
COG8 -346
SEC23IP -468
BET1 -594
MANEA -699
MAN2A1 -1349
GOSR2 -1456
ARFGAP1 -1942
MAN1A2 -2055
MGAT4C -2109
KDELR3 -2117
TRAPPC2L -2299
MGAT3 -2391
SEC24C -2569
NAPB -2780
MGAT5 -3072
COG5 -3259
SPTBN5 -3531
DYNLL2 -3980
DCTN5 -4086
SEC22C -4248
GBF1 -4290
ANK3 -4919
SEC22A -5052
SPTBN2 -5129
GOLGB1 -5370
COG3 -5426
MGAT4A -5680
ARFGAP2 -5786
COG6 -5811
B4GALT2 -6034
MIA3 -6245
ANKRD28 -6250
TRAPPC4 -6712
MAN1C1 -6804
BET1L -7405
DYNC1H1 -7685
SPTBN1 -7764
COG2 -7917
TRAPPC2 -8704
B4GALT6 -8785
CNIH3 -9011
TRAPPC10 -9369
FUT8 -9755
LMAN1 -10630
B4GALT3 -10759
COPZ2 -10863
TRAPPC6A -10917
STX17 -11006
SPTAN1 -11426
ST8SIA6 -11516
CHST10 -11841
ST6GAL1 -12052
COG1 -12125


Antigen processing-Cross presentation

Antigen processing-Cross presentation
75
set Antigen processing-Cross presentation
setSize 98
pANOVA 1.88e-11
s.dist 0.392
p.adjustANOVA 6.58e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
CD36 9444
FCGR1A 9323
NCF4 9268
NCF2 9190
TLR2 9103
CD14 9097
FCGR1B 9053
CYBB 9031
TLR4 9016
TLR1 8932
TLR6 8840
LY96 8795
SNAP23 8628
PSMB7 8485
PSMD4 8402
CTSS 8372
PSME3 8251
VAMP3 8222
MYD88 8136
PSMB5 8101

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CD36 9444
FCGR1A 9323
NCF4 9268
NCF2 9190
TLR2 9103
CD14 9097
FCGR1B 9053
CYBB 9031
TLR4 9016
TLR1 8932
TLR6 8840
LY96 8795
SNAP23 8628
PSMB7 8485
PSMD4 8402
CTSS 8372
PSME3 8251
VAMP3 8222
MYD88 8136
PSMB5 8101
CHUK 7966
PSMD6 7846
PSMD9 7620
PSMD2 7411
NCF1 7334
PSMA1 7329
PSMD1 7241
BTK 7206
PSMB3 7171
PSMA7 7096
PSMC1 7021
SEC61B 7013
ITGB5 6923
CYBA 6922
PSMB6 6813
PSMF1 6659
UBB 6639
PSMC6 6635
PSMD12 6556
SEC61A1 6449
CALR 6340
PSMD11 6231
ITGAV 6106
PSMA6 5970
PSMD7 5963
PSMD13 5948
SEC22B 5873
PSMD8 5757
TIRAP 5640
IKBKG 5377
PSMA2 5339
VAMP8 5218
SEC61G 4708
PSMD3 4618
UBC 4439
SEM1 4348
CTSL 4231
PDIA3 4128
PSMB2 4084
PSMD5 3426
PSMB1 3374
MRC1 3109
TAPBP 3010
PSMD14 2611
PSMC2 2598
PSMB4 2523
PSMC3 1976
PSMD10 1559
UBA52 1121
HLA-C 1018
HLA-B 649
STX4 606
MRC2 -165
PSMA4 -616
PSMC5 -863
HLA-G -2457
HLA-A -2573
CTSV -3036
PSMB8 -3076
HLA-H -3889
HLA-E -4415
PSMA3 -5285
IKBKB -5386
PSMB10 -5735
PSMA5 -6053
PSME4 -6087
B2M -6920
RPS27A -6938
PSMA8 -7606
PSMC4 -9127
LNPEP -9618
PSME1 -9991
PSME2 -10336
TAP1 -10787
SEC61A2 -10798
HLA-F -11138
PSMB9 -11324
TAP2 -11807


RHO GTPase Effectors

RHO GTPase Effectors
885
set RHO GTPase Effectors
setSize 250
pANOVA 2.78e-11
s.dist 0.244
p.adjustANOVA 9.48e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
WASF1 9520
S100A9 9516
S100A8 9503
H2AJ 9374
CTNNA1 9341
GRB2 9304
H2BC21 9283
NCF4 9268
CYFIP1 9265
YWHAG 9264
ARPC1B 9259
NCF2 9190
MAPK14 9104
H2BC12 9051
YWHAE 9045
CYBB 9031
ACTB 9011
PRKCD 9008
DLG4 9007
MAPK3 8953

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
WASF1 9520.0
S100A9 9516.0
S100A8 9503.0
H2AJ 9374.0
CTNNA1 9341.0
GRB2 9304.0
H2BC21 9283.0
NCF4 9268.0
CYFIP1 9265.0
YWHAG 9264.0
ARPC1B 9259.0
NCF2 9190.0
MAPK14 9104.0
H2BC12 9051.0
YWHAE 9045.0
CYBB 9031.0
ACTB 9011.0
PRKCD 9008.0
DLG4 9007.0
MAPK3 8953.0
ARPC1A 8894.0
RAC1 8793.0
ARPC5 8686.0
H3-3A 8661.0
YWHAH 8649.0
MYL6 8576.0
ACTG1 8562.0
WAS 8560.0
CLIP1 8540.0
DIAPH2 8523.0
RHOG 8487.0
WASF2 8369.0
MRTFA 8350.0
RHOA 8319.0
ARPC3 8277.0
TAX1BP3 8262.0
KIF5B 8239.0
PPP2CA 8234.0
PAK1 8230.0
CFL1 8186.0
PAK2 8185.0
B9D2 8168.0
IQGAP1 8152.0
LIMK2 8074.0
H2BC5 8003.0
H2AC6 7934.0
H2BC11 7912.0
ACTR2 7870.0
ACTR3 7818.0
DYNC1I2 7735.0
PPP2CB 7712.0
MYL9 7703.0
NCKAP1L 7673.0
MAPRE1 7658.0
NDEL1 7627.0
CDC42 7537.0
ARPC4 7516.0
RHOQ 7511.0
MAPK1 7493.0
ROCK1 7489.0
NCKAP1 7462.0
ARPC2 7390.0
H2BC4 7389.0
KLC3 7377.0
NCF1 7334.0
H2BC17 7285.0
BTK 7206.0
PRKCB 7097.0
ABI1 7082.0
SRF 7079.0
PPP1CB 7064.0
BRK1 7032.0
DYNC1LI1 6941.0
CYBA 6922.0
PPP1R14A 6839.0
WASF3 6808.0
PPP2R5B 6774.0
H3C15 6699.5
MYH9 6685.0
MYLK 6618.0
IQGAP2 6599.0
CTNNB1 6408.0
YWHAB 6385.0
PPP1CC 6330.0
SRGAP2 6171.0
ROCK2 6138.0
PDPK1 6136.0
PPP1R12A 6050.0
H2AZ1 6036.0
DYNLL1 5952.0
CTTN 5930.0
PPP2R5A 5897.0
SEC13 5748.0
WIPF2 5713.0
DVL3 5656.0
YWHAZ 5624.0
KLC1 5523.0
PAFAH1B1 5470.0
PFN1 5459.0
TAOK1 5420.0
NSL1 5408.0
H2BC9 5394.0
H2BC15 5312.0
RAC2 5163.0
MYL12B 5088.0
H2AC20 4972.0
CDC25C 4969.0
AR 4840.0
LIMK1 4679.0
PPP2R1A 4589.0
PTK2 4462.0
DIAPH3 4379.0
DYNC1LI2 4273.0
DYNC1I1 4187.0
CENPA 4162.0
FMNL1 4150.0
CDC20 3998.0
MAPK11 3826.0
BIRC5 3738.0
DAAM1 3466.0
IQGAP3 3370.0
PMF1 3364.0
KTN1 3363.0
BUB1 3362.0
KIF14 3352.0
NUP98 3101.0
NUP37 3074.0
KLK2 3029.0
PLK1 3002.0
BUB1B 2997.0
CENPF 2723.0
SKA1 2649.0
NDE1 2594.0
PPP2R5D 2421.0
CFTR 2416.0
SPC24 2306.0
PPP1R12B 1775.0
PIK3C3 1619.0
SFN 1615.0
RHOB 1254.0
PRKCA 1132.0
NCOA2 1092.0
PRC1 980.0
AURKB 846.0
KIF2C 726.0
MYH10 653.0
WIPF1 569.0
FLNA 483.0
CENPE 332.0
NCKIPSD 328.0
WASL 299.0
ABL1 226.0
PKN2 98.0
ZW10 31.0
CENPN 20.0
DVL1 0.0
ITGB1 -94.0
BAIAP2 -215.0
PPP2R1B -241.0
ERCC6L -415.0
KNL1 -581.0
CLASP1 -588.0
PPP2R5E -680.0
NUDC -709.0
RANBP2 -820.0
DIAPH1 -854.0
KIF2A -1069.0
XPO1 -1185.0
H2AZ2 -1209.0
AHCTF1 -1644.0
CDCA8 -1838.0
CALM1 -2081.0
CLASP2 -2151.0
PKN1 -2208.0
PFN2 -2339.0
KIF18A -2742.0
NUP85 -3049.0
CENPI -3162.0
PIN1 -3188.0
SGO2 -3480.0
MYH11 -3522.0
LIN7B -3725.0
PKN3 -3793.0
DYNLL2 -3980.0
PIK3R4 -4062.0
PAK3 -4184.0
NUF2 -4301.0
FMNL2 -4424.0
RHPN2 -4650.0
ZWINT -4742.0
MAD1L1 -4981.0
CIT -5064.0
CENPO -5135.0
RCC2 -5148.0
RHPN1 -5327.0
CENPM -5376.0
NOXA1 -5464.0
INCENP -5956.0
SEH1L -6069.0
CKAP5 -6246.0
CENPQ -6366.0
NF2 -6540.0
H2BU1 -6555.0
CENPU -6692.0
SGO1 -6715.0
YWHAQ -7340.0
ITGB3BP -7621.0
DYNC1H1 -7685.0
NUP133 -7762.0
SCAI -7879.0
KNTC1 -7897.0
MAD2L1 -7944.0
CDKN1B -8207.0
CENPK -8334.0
KLC4 -8376.0
MEN1 -8538.0
CENPH -8633.0
SRC -8820.0
KIF5A -8869.0
SKA2 -8999.0
KLC2 -9059.0
NDC80 -9165.0
KDM1A -9430.0
NUP43 -9517.0
CENPT -9606.0
RPS27 -9756.0
GOPC -9831.0
CYFIP2 -10367.0
NUP107 -10421.0
NUP160 -10557.0
KDM4C -10749.0
DSN1 -10773.0
MIS12 -10903.0
ABI2 -10915.0
DVL2 -11152.0
PPP2R5C -11265.0
RHOC -11360.0
NCK1 -11454.0
CDH1 -11500.0
SPDL1 -11534.0
PRKCZ -11629.0
BUB3 -11709.0
RANGAP1 -11722.0
ZWILCH -11724.0
CENPL -11782.0
CENPP -11814.0
CENPC -11888.0
FMNL3 -12087.0
EVL -12207.0
RTKN -12249.0


MyD88 dependent cascade initiated on endosome

MyD88 dependent cascade initiated on endosome
687
set MyD88 dependent cascade initiated on endosome
setSize 89
pANOVA 4.41e-11
s.dist 0.404
p.adjustANOVA 1.43e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
TLR8 9343
DUSP3 9280
APP 9177
MAPK14 9104
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
MAP2K6 8887
LY96 8795
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
TLR8 9343
DUSP3 9280
APP 9177
MAPK14 9104
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
MAP2K6 8887
LY96 8795
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966
PELI3 7716
PPP2CB 7712
RPS6KA1 7695
MAPK1 7493
TAB2 6964
MAP2K4 6866
NFKBIA 6807
PELI1 6715
UBB 6639
TICAM2 6335
TICAM1 6307
NFKB1 6277
FBXW11 6196
MAP3K8 6160
IRAK1 6131
ATF1 5706
TAB1 5681
UBE2V1 5637
TNIP2 5552
FOS 5460
IKBKG 5377
MAP3K1 5121
ECSIT 4918
PPP2R1A 4589
UBC 4439
DUSP6 4357
MAPK10 4325
SKP1 4287
MAPKAPK2 4054
MAPK11 3826
JUN 3722
TAB3 3160
RPS6KA2 3087
RPS6KA3 2973
PPP2R5D 2421
MAP3K7 2395
ATF2 2085
UBE2N 1936
MAP2K7 1654
AGER 1294
VRK3 1281
UBA52 1121
ELK1 1040
RIPK2 1025
NKIRAS1 375
NFKBIB -152
TRAF6 -229
PPP2R1B -241
HMGB1 -252
MEF2C -293
TLR7 -625
NFKB2 -1165
MAPK7 -1337
CREB1 -1378
RELA -1803
DUSP7 -3211
BTRC -4924
IKBKB -5386
S100B -5457
TLR9 -5999
DUSP4 -6287
RPS27A -6938
MAPK9 -7068
IRF7 -8657
MAPK8 -9428
IRAK2 -9548
CUL1 -11330
RPS6KA5 -11594
NOD1 -12263


Toll Like Receptor 7/8 (TLR7/8) Cascade

Toll Like Receptor 7/8 (TLR7/8) Cascade
1241
set Toll Like Receptor 7/8 (TLR7/8) Cascade
setSize 89
pANOVA 4.41e-11
s.dist 0.404
p.adjustANOVA 1.43e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
TLR8 9343
DUSP3 9280
APP 9177
MAPK14 9104
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
MAP2K6 8887
LY96 8795
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
TLR8 9343
DUSP3 9280
APP 9177
MAPK14 9104
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
MAP2K6 8887
LY96 8795
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966
PELI3 7716
PPP2CB 7712
RPS6KA1 7695
MAPK1 7493
TAB2 6964
MAP2K4 6866
NFKBIA 6807
PELI1 6715
UBB 6639
TICAM2 6335
TICAM1 6307
NFKB1 6277
FBXW11 6196
MAP3K8 6160
IRAK1 6131
ATF1 5706
TAB1 5681
UBE2V1 5637
TNIP2 5552
FOS 5460
IKBKG 5377
MAP3K1 5121
ECSIT 4918
PPP2R1A 4589
UBC 4439
DUSP6 4357
MAPK10 4325
SKP1 4287
MAPKAPK2 4054
MAPK11 3826
JUN 3722
TAB3 3160
RPS6KA2 3087
RPS6KA3 2973
PPP2R5D 2421
MAP3K7 2395
ATF2 2085
UBE2N 1936
MAP2K7 1654
AGER 1294
VRK3 1281
UBA52 1121
ELK1 1040
RIPK2 1025
NKIRAS1 375
NFKBIB -152
TRAF6 -229
PPP2R1B -241
HMGB1 -252
MEF2C -293
TLR7 -625
NFKB2 -1165
MAPK7 -1337
CREB1 -1378
RELA -1803
DUSP7 -3211
BTRC -4924
IKBKB -5386
S100B -5457
TLR9 -5999
DUSP4 -6287
RPS27A -6938
MAPK9 -7068
IRF7 -8657
MAPK8 -9428
IRAK2 -9548
CUL1 -11330
RPS6KA5 -11594
NOD1 -12263


Toll Like Receptor 9 (TLR9) Cascade

Toll Like Receptor 9 (TLR9) Cascade
1242
set Toll Like Receptor 9 (TLR9) Cascade
setSize 93
pANOVA 7.92e-11
s.dist 0.39
p.adjustANOVA 2.51e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
TLR8 9343
DUSP3 9280
APP 9177
MAPK14 9104
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
MAP2K6 8887
LY96 8795
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
TLR8 9343
DUSP3 9280
APP 9177
MAPK14 9104
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
MAP2K6 8887
LY96 8795
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966
PELI3 7716
PPP2CB 7712
RPS6KA1 7695
MAPK1 7493
TAB2 6964
MAP2K4 6866
NFKBIA 6807
PELI1 6715
UBB 6639
TICAM2 6335
TICAM1 6307
NFKB1 6277
FBXW11 6196
MAP3K8 6160
IRAK1 6131
ATF1 5706
TAB1 5681
UBE2V1 5637
TNIP2 5552
FOS 5460
IKBKG 5377
MAP3K1 5121
ECSIT 4918
EEA1 4641
PPP2R1A 4589
UBC 4439
DUSP6 4357
MAPK10 4325
SKP1 4287
MAPKAPK2 4054
MAPK11 3826
JUN 3722
TAB3 3160
RPS6KA2 3087
RPS6KA3 2973
PPP2R5D 2421
MAP3K7 2395
ATF2 2085
UBE2N 1936
MAP2K7 1654
PIK3C3 1619
AGER 1294
VRK3 1281
UBA52 1121
ELK1 1040
RIPK2 1025
NKIRAS1 375
NFKBIB -152
TRAF6 -229
PPP2R1B -241
HMGB1 -252
MEF2C -293
TLR7 -625
NFKB2 -1165
MAPK7 -1337
CREB1 -1378
RELA -1803
DUSP7 -3211
PIK3R4 -4062
RBSN -4542
BTRC -4924
IKBKB -5386
S100B -5457
TLR9 -5999
DUSP4 -6287
RPS27A -6938
MAPK9 -7068
IRF7 -8657
MAPK8 -9428
IRAK2 -9548
CUL1 -11330
RPS6KA5 -11594
NOD1 -12263


Signaling by NTRK1 (TRKA)

Signaling by NTRK1 (TRKA)
1117
set Signaling by NTRK1 (TRKA)
setSize 101
pANOVA 1.31e-10
s.dist 0.37
p.adjustANOVA 4.06e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
GRB2 9304
DUSP3 9280
RIT1 9121
MAPK14 9104
MAP2K1 9063
PIK3CB 9038
CLTC 9000
MAPK3 8953
CRK 8906
FOSL1 8788
AP2M1 8627
CDK5 8616
IRS2 8569
RALB 8414
MAPKAPK3 8382
CLTA 8376
RHOA 8319
PPP2CA 8234
LYL1 8221
STAT3 8098

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GRB2 9304
DUSP3 9280
RIT1 9121
MAPK14 9104
MAP2K1 9063
PIK3CB 9038
CLTC 9000
MAPK3 8953
CRK 8906
FOSL1 8788
AP2M1 8627
CDK5 8616
IRS2 8569
RALB 8414
MAPKAPK3 8382
CLTA 8376
RHOA 8319
PPP2CA 8234
LYL1 8221
STAT3 8098
AP2S1 8026
MEF2A 8009
PPP2CB 7712
RPS6KA1 7695
TRIB1 7643
MAPK1 7493
RAP1A 7305
AP2A2 7257
SRF 7079
KIDINS220 7069
DNM3 7045
AP2A1 6832
JUNB 6806
MAP2K2 6794
YWHAB 6385
EP300 6129
DNM2 6089
ATF1 5706
FOS 5460
NRAS 5363
PIK3R2 5010
ID1 4927
PIK3CA 4629
SGK1 4595
PPP2R1A 4589
DUSP6 4357
SHC2 4183
SHC1 4161
MAPKAPK2 4054
SHC3 3974
CRKL 3966
MAP2K5 3940
MAPK13 3865
MAPK11 3826
KRAS 3702
DNM1 3587
DNAL4 3398
ADORA2A 3293
EGR1 3124
RPS6KA2 3087
RPS6KA3 2973
RALA 2710
PPP2R5D 2421
ATF2 2085
IRS1 1741
JUND 1549
FOSB 1368
NAB1 1342
BRAF 1308
VRK3 1281
TF 1102
ELK1 1040
REST 865
EGR3 44
PPP2R1B -241
MEF2C -293
MAPK12 -1074
CDK5R1 -1089
TCF12 -1233
MAPK7 -1337
CREB1 -1378
EGR2 -1435
AP2B1 -2709
MEF2D -3094
DUSP7 -3211
HRAS -3382
FRS2 -3433
CHD4 -4515
SOS1 -5700
DUSP4 -6287
NTRK1 -8193
TPH1 -8640
SRC -8820
PIK3R1 -9505
ID3 -9614
RAPGEF1 -9826
NAB2 -10400
ID2 -10969
PLCG1 -11120
RPS6KA5 -11594
RALGDS -12140


Translocation of ZAP-70 to Immunological synapse

Translocation of ZAP-70 to Immunological synapse
1278
set Translocation of ZAP-70 to Immunological synapse
setSize 24
pANOVA 2.81e-10
s.dist -0.744
p.adjustANOVA 8.52e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
CD247 -12345
HLA-DPA1 -12316
HLA-DPB1 -12248
HLA-DRA -12009
TRBC1 -12006
HLA-DQA1 -11992
ZAP70 -11949
LCK -11838
CD3G -11526
TRAC -11482
CD3D -11401
CD3E -11302
TRBV12-3 -10436
TRAV19 -9915
TRAV29DV5 -9673
TRBV7-9 -9539
HLA-DQB2 -9401
HLA-DRB1 -8075
TRAV8-4 -7261
HLA-DQB1 -6416

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CD247 -12345
HLA-DPA1 -12316
HLA-DPB1 -12248
HLA-DRA -12009
TRBC1 -12006
HLA-DQA1 -11992
ZAP70 -11949
LCK -11838
CD3G -11526
TRAC -11482
CD3D -11401
CD3E -11302
TRBV12-3 -10436
TRAV19 -9915
TRAV29DV5 -9673
TRBV7-9 -9539
HLA-DQB2 -9401
HLA-DRB1 -8075
TRAV8-4 -7261
HLA-DQB1 -6416
CD4 -5406
HLA-DRB5 -4971
HLA-DQA2 -4806
PTPN22 -1208


Gene expression (Transcription)

Gene expression (Transcription)
444
set Gene expression (Transcription)
setSize 1335
pANOVA 4e-10
s.dist -0.102
p.adjustANOVA 1.19e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
FASLG -12371
TFDP2 -12364
RUNX3 -12352
ERBB2 -12320
SUV39H1 -12319
NFATC2 -12294
DNMT1 -12257
ZNF599 -12232
PTPN4 -12220
RAD1 -12206
MYBL1 -12195
GATA3 -12191
NDC1 -12173
ZNF287 -12168
ZNF3 -12165
RBBP7 -12155
YES1 -12142
PRKCQ -12127
AUTS2 -12089
ZNF530 -12068

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FASLG -12371.0
TFDP2 -12364.0
RUNX3 -12352.0
ERBB2 -12320.0
SUV39H1 -12319.0
NFATC2 -12294.0
DNMT1 -12257.0
ZNF599 -12232.0
PTPN4 -12220.0
RAD1 -12206.0
MYBL1 -12195.0
GATA3 -12191.0
NDC1 -12173.0
ZNF287 -12168.0
ZNF3 -12165.0
RBBP7 -12155.0
YES1 -12142.0
PRKCQ -12127.0
AUTS2 -12089.0
ZNF530 -12068.0
MDC1 -12059.0
WRN -12047.0
TP53RK -12040.0
PHF19 -12016.0
ZNF74 -12012.0
RPA1 -12004.0
MOV10 -11991.0
PRR5 -11985.0
RORA -11979.0
ANAPC1 -11962.0
ZNF461 -11956.0
FANCI -11927.0
ZNF33B -11911.0
ZNF549 -11908.0
ZNF250 -11889.0
DLL1 -11885.0
SMAD7 -11872.0
GLS -11862.0
NUAK1 -11853.0
AKT3 -11849.0
ZNF70 -11832.0
TNRC6C -11828.0
CAMK2D -11816.0
ZNF43 -11813.0
ZNF682 -11811.0
ZNF500 -11806.0
DYRK2 -11799.0
DGCR8 -11798.0
ZNF286A -11794.0
ZNF571 -11792.0
ZNF607 -11784.0
POLR3D -11777.0
PARP1 -11764.0
POLR1E -11762.0
SMAD3 -11745.0
CCND2 -11734.0
ZNF620 -11732.0
STAT1 -11727.0
RFC5 -11712.0
CCNE1 -11707.0
ZNF736 -11692.0
ZNF696 -11688.0
MYBBP1A -11680.0
SMARCD1 -11679.0
ZNF568 -11661.0
ZNF554 -11652.0
PPP1R13B -11636.0
NUP188 -11624.0
NUP93 -11620.0
BRIP1 -11605.0
ZNF337 -11599.0
NR2C2AP -11589.0
ZNF724 -11586.0
ZNF517 -11582.0
ZNF570 -11569.0
FANCC -11548.0
COX11 -11539.0
DDB2 -11530.0
ZNF569 -11521.0
ZNF235 -11519.0
ATRIP -11486.0
MSH2 -11484.0
ZNF566 -11481.0
ZNF496 -11478.0
JMY -11472.0
ZNF707 -11464.0
ZNF30 -11462.0
KRBOX4 -11452.0
ZNF419 -11446.0
ZNF740 -11444.0
RAD9A -11435.0
ZNF136 -11433.0
RNPS1 -11427.0
FANCD2 -11424.0
RAD51D -11415.0
RRN3 -11408.0
CENPJ -11406.0
NUP88 -11397.0
ZNF773 -11396.0
POLR3E -11383.0
PIP4K2C -11371.0
ZNF138 -11364.0
SUPT16H -11359.0
ZNF211 -11357.0
ZNF551 -11356.0
ZNF202 -11351.0
ZNF510 -11341.0
CUL1 -11330.0
PSMB9 -11324.0
NUP205 -11321.0
ZNF600 -11320.0
CDC23 -11304.0
ZNF383 -11291.0
ZNF660 -11282.0
PPP2R5C -11265.0
CDK4 -11256.0
CNOT6L -11248.0
ZKSCAN8 -11246.0
ZNF528 -11244.0
ZNF248 -11241.0
PHF1 -11227.0
ZNF649 -11216.0
ZNF354C -11213.0
ZNF14 -11212.0
ZNF343 -11182.0
ZFP30 -11171.0
RUNX2 -11163.0
SSRP1 -11162.0
ATM -11148.0
ZNF75D -11137.0
ZNF550 -11136.0
ZNF584 -11134.0
ZNF133 -11128.0
SKI -11113.0
ZNF519 -11101.0
ZNF540 -11097.0
RNMT -11086.0
WWOX -11085.0
ZNF77 -11084.0
PLXNA4 -11083.0
ZNF184 -11077.0
SRSF5 -11067.0
PCBP4 -11063.0
ZNF548 -11049.0
ITGA4 -11043.0
ZIK1 -11040.0
ZNF19 -11034.0
ZNF678 -11020.0
ZNF621 -11018.0
POLR1B -11015.0
KIT -11004.0
BRD1 -10991.0
PMAIP1 -10986.0
ZNF324B -10972.0
ANAPC5 -10967.0
ZNF226 -10966.0
TET1 -10957.0
ZNF432 -10951.0
ZNF703 -10910.0
ZNF441 -10905.0
POLR1C -10899.0
TP53 -10893.0
ZNF10 -10857.0
MECP2 -10855.0
ITGAL -10847.0
TP63 -10842.0
ZNF302 -10830.0
DROSHA -10799.0
KAT2A -10771.0
L3MBTL2 -10770.0
XPO5 -10734.0
NUP210 -10726.0
KMT2A -10725.0
ZNF257 -10712.0
RFC4 -10702.0
ZNF23 -10692.0
ZNF180 -10670.0
ERCC6 -10662.0
ATAD2 -10660.0
ZNF253 -10652.0
POLRMT -10641.0
PRMT6 -10628.0
NR3C2 -10625.0
NUP35 -10611.0
FBXO32 -10607.0
ZNF585B -10598.0
ZNF266 -10587.0
DAXX -10575.0
ZNF563 -10567.0
ZFP1 -10563.0
NUP160 -10557.0
ZNF790 -10520.0
MAF -10499.0
SIN3A -10493.0
ZNF420 -10490.0
RFC3 -10489.0
ZNF675 -10478.0
ZNF529 -10469.0
RPTOR -10464.0
ZNF544 -10460.0
ZNF749 -10456.0
ZNF473 -10444.0
SMYD2 -10431.0
NUP107 -10421.0
LSM11 -10415.0
ZNF595 -10393.0
CTLA4 -10363.0
ATR -10354.0
ZNF92 -10349.0
SMURF2 -10340.0
PSME2 -10336.0
ZNF112 -10327.0
NR1D2 -10325.0
POLR3H -10310.0
RAD17 -10307.0
LDB1 -10303.0
ZNF778 -10297.0
ZNF680 -10286.0
AXIN1 -10285.0
IFNG -10277.0
ZNF446 -10274.0
GPAM -10241.0
THOC1 -10238.0
NUP155 -10233.0
ZNF799 -10216.0
ZFPM1 -10195.0
TCF7 -10173.0
ZFP14 -10160.0
ZNF212 -10128.0
WWP1 -10106.0
TGIF2 -10105.0
TDRKH -10103.0
ZNF737 -10092.0
ZC3H8 -10090.0
LRPPRC -10081.0
ING5 -10037.0
UBTF -10033.0
MLLT3 -10022.0
ZNF626 -10014.0
SRSF11 -10002.0
PSME1 -9991.0
ZNF224 -9977.0
PERP -9973.0
NFYB -9964.0
POLR1A -9963.0
RBL1 -9959.0
CAMK4 -9956.0
NOP2 -9952.0
MGA -9948.0
ZNF436 -9945.0
EPC1 -9926.0
NR2C1 -9913.0
ZNF26 -9910.0
ZNF45 -9897.0
ZNF483 -9883.0
ZNF324 -9879.0
ZNF596 -9874.0
ZNF708 -9864.0
ZNF573 -9862.0
ZNF582 -9837.0
BMI1 -9829.0
ZNF664 -9828.0
SCO1 -9819.0
ZNF227 -9818.0
ZNF485 -9810.0
ZNF263 -9806.0
GATA2 -9800.0
MED15 -9778.0
MTOR -9767.0
HEY2 -9752.0
EZH2 -9741.0
CHD3 -9737.0
ZNF157 -9718.0
ZNF583 -9711.0
ZNF311 -9705.0
BRD2 -9688.0
RICTOR -9670.0
ZNF704 -9660.0
ZNF793 -9654.0
ZNF597 -9642.0
ZNF431 -9641.0
ZNF470 -9630.0
ZFP90 -9613.0
TXNIP -9600.0
ZNF354B -9598.0
ZNF684 -9580.0
ZNF614 -9572.0
ZNF689 -9559.0
NCBP2 -9558.0
NPM1 -9532.0
ZNF484 -9525.0
NUP43 -9517.0
ZSCAN25 -9513.0
ZFP69 -9488.0
RRP8 -9484.0
CCNT1 -9469.0
FOXO1 -9465.0
IGFBP3 -9455.0
ZNF506 -9443.0
MTA3 -9433.0
CPSF4 -9416.0
ZNF41 -9405.0
ZNF17 -9349.0
EED -9348.0
TRPC3 -9343.0
ZNF767P -9339.0
ZNF625 -9336.0
MAGOHB -9327.0
ZNF606 -9322.0
INTS4 -9307.0
CBX5 -9272.0
ESR2 -9250.0
GTF3C2 -9243.0
PRMT1 -9229.0
MED27 -9191.0
TWISTNB -9189.0
PRKRA -9188.0
AEBP2 -9176.0
TBP -9167.0
ZNF141 -9154.0
ZNF677 -9144.0
PSMC4 -9127.0
ESR1 -9122.0
ZNF727 -9121.0
ZNF782 -9113.0
ZNF738 -9086.0
ZNF709 -9071.0
ZNF699 -9037.0
ZNF317 -9010.0
ZNF439 -9000.0
ZNF160 -8989.0
ZNF567 -8988.0
NR1D1 -8980.0
SESN1 -8962.0
ICE2 -8945.0
RPAP2 -8928.0
ZNF721 -8922.0
RPA3 -8911.0
ZNF416 -8903.0
ZNF681 -8899.0
SRSF7 -8892.0
SMARCC1 -8880.0
SIRT3 -8857.0
PRDM1 -8856.0
ZNF792 -8839.0
TRIM33 -8823.0
SRC -8820.0
ZNF433 -8780.0
ZNF79 -8769.0
BRF1 -8767.0
ZNF140 -8760.0
ZNF619 -8735.0
ZNF440 -8730.0
AIFM2 -8727.0
ZNF717 -8709.0
ZNF331 -8698.0
PML -8693.0
EHMT1 -8692.0
MNAT1 -8687.0
TGIF1 -8682.0
ZNF274 -8667.0
GTF3C1 -8638.0
NR2C2 -8630.0
MED10 -8579.0
RORC -8573.0
E2F5 -8568.0
EHMT2 -8558.0
MEN1 -8538.0
ZFP37 -8513.0
FOXP3 -8503.0
ZNF234 -8487.0
ZNF300 -8481.0
NUP54 -8479.0
TAF1 -8476.0
ZNF559 -8467.0
L3MBTL1 -8461.0
SF3B1 -8426.0
PHC1 -8402.0
CDK13 -8392.0
AAAS -8389.0
ICE1 -8382.0
MAPKAPK5 -8364.0
SNAPC3 -8359.0
HENMT1 -8357.0
SMAD4 -8351.0
HDAC6 -8337.0
POM121 -8299.0
UPF3B -8288.0
SKP2 -8279.0
HES1 -8266.0
CDKN1B -8207.0
PRKAB2 -8172.0
PHC3 -8152.0
ZKSCAN3 -8126.0
MEAF6 -8105.0
LEF1 -8076.0
TAF4B -8069.0
ZNF720 -8041.0
ZNF665 -7990.0
ZNF175 -7950.0
THOC3 -7934.0
FIP1L1 -7928.0
MRE11 -7923.0
GLI3 -7910.0
INTS7 -7902.0
ZNF726 -7889.0
ZNF641 -7885.0
ZNF688 -7872.0
BBC3 -7864.0
CDC7 -7855.0
ZNF135 -7853.0
ZNF521 -7834.0
ZNF12 -7825.0
RGCC -7821.0
ZNF585A -7814.0
ZNF671 -7797.0
PIP4K2B -7788.0
ERCC3 -7783.0
SAP30BP -7774.0
NUP133 -7762.0
ZNF75A -7752.0
RBL2 -7743.0
ZNF382 -7731.0
TNFRSF18 -7726.0
WDR33 -7715.0
GLS2 -7702.0
ZNF702P -7701.0
ZNF771 -7686.0
ZNF2 -7673.0
ZNF320 -7647.0
PIWIL2 -7631.0
ZNF273 -7623.0
PSMA8 -7606.0
ZNF577 -7605.0
ZNF418 -7559.0
ZNF791 -7534.0
RBM14 -7497.0
POLR3GL -7481.0
GTF3A -7469.0
ACTL6A -7468.0
POLR3C -7421.0
ZNF264 -7412.0
ANAPC2 -7407.0
RBM8A -7393.0
MED24 -7387.0
YAF2 -7378.0
RAD50 -7373.0
POLR3B -7356.0
TAF6 -7352.0
YWHAQ -7340.0
POLR3A -7324.0
MTA2 -7317.0
ZNF711 -7253.0
ZNF195 -7249.0
NABP2 -7240.0
BRPF1 -7218.0
TCF3 -7215.0
BDP1 -7192.0
POM121C -7188.0
IL2RA -7161.0
GAMT -7054.0
ZNF785 -7032.0
TPR -7028.0
ZNF777 -6997.0
CCND1 -6970.0
RPS27A -6938.0
ZNF764 -6912.0
ZNF786 -6907.0
ZNF223 -6903.0
ZNF425 -6900.0
ZNF268 -6887.0
COX19 -6882.0
MLH1 -6872.0
ZFP28 -6824.0
RAN -6791.0
MED23 -6787.0
NR4A1 -6756.0
SUPT5H -6716.0
PIDD1 -6647.0
ANAPC4 -6644.0
ZNF33A -6630.0
ZNF691 -6627.0
BRPF3 -6615.0
ZKSCAN7 -6609.0
TAF1D -6605.0
FBXW7 -6600.0
GAD2 -6585.0
ZNF415 -6564.0
H2BU1 -6555.0
DDX39A -6544.0
INTS9 -6543.0
CDK6 -6465.0
ZNF480 -6459.0
TAF15 -6454.0
CSTF2 -6444.0
RHNO1 -6437.0
SUPT6H -6407.0
SRSF2 -6396.0
PPARD -6394.0
THRA -6387.0
ZNF616 -6382.0
TJP1 -6374.0
FOXO6 -6367.0
ZNF208 -6363.0
NUP153 -6321.0
RPA2 -6306.0
NELFCD -6277.0
TFAP2E -6266.0
AGRP -6243.0
ZNF169 -6234.0
ZNF442 -6204.0
TCF7L2 -6185.0
ZNF610 -6184.0
CSTF2T -6171.0
RNF34 -6150.0
WWTR1 -6131.0
SYMPK -6129.0
COX18 -6126.0
CSTF1 -6113.0
KRBA1 -6098.0
PSME4 -6087.0
KMT2E -6073.0
CDC16 -6071.0
SEH1L -6069.0
PSMA5 -6053.0
ZNF706 -6049.0
ZNF493 -6035.0
ZNF557 -5971.0
PCNA -5969.0
ZNF662 -5963.0
TAF1A -5947.0
ZNF154 -5946.0
TAF2 -5945.0
ZNF543 -5942.0
NCBP1 -5853.0
ZNF398 -5842.0
SCMH1 -5839.0
GTF3C5 -5834.0
NOC2L -5831.0
ZNF761 -5813.0
FYTTD1 -5794.0
E2F7 -5780.0
SETD1A -5744.0
PSMB10 -5735.0
TDRD6 -5673.0
TAF1B -5671.0
ZNF713 -5668.0
ZNF514 -5664.0
ZNF718 -5657.0
ZNF101 -5614.0
TNRC6A -5613.0
MAMLD1 -5584.0
ZNF658 -5581.0
ZNF34 -5577.0
NUP42 -5564.0
ZFP69B -5558.0
ZNF71 -5533.0
ZNF589 -5519.0
PMS2 -5514.0
ARID1B -5504.0
TNKS1BP1 -5490.0
MED30 -5484.0
ZNF25 -5459.0
ZNF417 -5416.0
SRSF6 -5402.0
POLR3G -5401.0
ZNRD1 -5389.0
BLK -5388.0
MTERF1 -5387.0
ZNF99 -5349.0
ZNF615 -5323.0
ZNF547 -5291.0
PSMA3 -5285.0
PHAX -5261.0
SRRT -5248.0
RABGGTB -5240.0
ZNF285 -5239.0
CDKN2A -5236.0
ZNF37A -5230.0
NOTCH4 -5229.0
CCNT2 -5205.0
BTG1 -5201.0
POLR3F -5191.0
ANAPC7 -5181.0
ZKSCAN4 -5161.0
RARG -5153.0
ZNF443 -5146.0
RBBP8 -5105.0
NR4A3 -5082.0
TRIM28 -5056.0
SRRM1 -5050.0
PPARGC1B -5047.0
COX20 -5018.0
ZNF155 -5014.0
CDK2 -5006.0
ANAPC10 -5000.0
TFAM -4988.0
E2F6 -4979.0
SOCS4 -4974.0
ZNF124 -4952.0
ZNF430 -4837.0
ZNF546 -4802.0
TP73 -4754.0
ZNF692 -4722.0
ZNF700 -4710.0
BLM -4690.0
GTF3C4 -4686.0
ZNF611 -4678.0
ZNF492 -4623.0
DHX38 -4620.0
CBX2 -4617.0
TFB2M -4521.0
ZNF564 -4519.0
TNRC6B -4518.0
CHD4 -4515.0
TAF5 -4514.0
RPRD2 -4513.0
ZNF460 -4477.0
NR1I2 -4435.0
ZNF197 -4430.0
ZNF426 -4382.0
BAZ1B -4373.0
SCO2 -4351.0
CHEK2 -4350.0
MTF2 -4329.0
SMARCE1 -4315.0
U2AF1L4 -4295.0
ZNF561 -4292.0
CNOT1 -4265.0
DDX39B -4243.0
SIN3B -4205.0
SIRT1 -4197.0
SMARCC2 -4137.0
PCGF2 -4135.0
RING1 -4063.0
RMI2 -4050.0
ZNF486 -4043.0
MED1 -4036.0
POLR2D -4024.0
ARID2 -3932.0
ZNF233 -3931.0
CDK9 -3927.0
YEATS4 -3919.0
NELFA -3886.0
CNOT7 -3880.0
PLD6 -3870.0
SMARCB1 -3869.0
PRELID3A -3832.0
CPSF1 -3813.0
SNAPC5 -3794.0
TEAD2 -3774.0
ZNF334 -3744.0
ZSCAN32 -3733.0
ZNF215 -3708.0
NUDT21 -3702.0
TDRD12 -3699.0
PAX5 -3638.0
BCDIN3D -3621.0
NR1H3 -3597.0
ZNF676 -3587.0
ZNF701 -3558.0
SESN3 -3546.0
GPX2 -3533.0
ZNF350 -3507.0
ZNF655 -3460.0
ZNF556 -3455.0
TOPBP1 -3450.0
CASP10 -3446.0
BARD1 -3419.0
ASZ1 -3372.0
BCL2L14 -3367.0
PCGF5 -3312.0
ZNF714 -3298.0
ZNF624 -3294.0
RXRB -3276.0
TARBP2 -3257.0
UXT -3252.0
PIN1 -3188.0
ZFP2 -3134.0
ZNF221 -3101.0
POLR2A -3092.0
PSMB8 -3076.0
ZNF670 -3075.0
NUP85 -3049.0
DNMT3A -3039.0
CTSV -3036.0
TAF1C -3035.0
PCF11 -3032.0
MTA1 -3005.0
POLR2H -2942.0
TAF11 -2938.0
GTF2H4 -2916.0
GTF2H1 -2913.0
DNA2 -2858.0
SSB -2848.0
CASP6 -2831.0
HIVEP3 -2798.0
RAD51 -2767.0
PLK2 -2748.0
ZNF555 -2741.0
SMARCA2 -2737.0
CNOT10 -2718.0
TTC5 -2650.0
ZNF490 -2630.0
ABCA6 -2612.0
TAF9B -2599.0
SMURF1 -2591.0
ZNF605 -2576.0
ZNF18 -2548.0
POLR2B -2523.0
ZNF772 -2509.0
CHEK1 -2481.0
CASP2 -2471.0
POLR3K -2467.0
RABGGTA -2462.0
KAT2B -2414.0
SUZ12 -2409.0
SNRPB -2400.0
DDIT4 -2395.0
SNRPF -2377.0
PIP4K2A -2365.0
H19 -2361.0
ZNF860 -2350.0
OCLN -2327.0
SMARCA5 -2306.0
SRSF3 -2292.0
BAZ2A -2275.0
GTF3C3 -2271.0
GTF2H3 -2235.0
FZR1 -2233.0
ZC3H11A -2210.0
ZNF839 -2202.0
ANAPC16 -2123.0
TSC1 -2118.0
CNOT2 -2090.0
CALM1 -2081.0
CDK8 -1971.0
INTS2 -1936.0
PHF20 -1921.0
KCTD1 -1890.0
RBBP4 -1870.0
HSPD1 -1860.0
TAF3 -1850.0
RELA -1803.0
POLR2K -1783.0
GATAD2B -1759.0
NR2F1 -1717.0
ZNF468 -1709.0
TAF4 -1698.0
RNU1-1 -1690.5
RFFL -1683.0
ZNF669 -1660.0
ZNF28 -1618.0
NR4A2 -1601.0
EXO1 -1586.0
COX14 -1496.0
BGLAP -1473.0
CHTOP -1387.0
CREB1 -1378.0
CDK12 -1356.0
ZNF750 -1354.0
SAP130 -1339.0
CYCS -1334.0
CNOT4 -1286.0
SETD9 -1240.0
TCF12 -1233.0
MDM4 -1230.0
H2AZ2 -1209.0
CDK5R1 -1089.0
STUB1 -1032.0
ZNF627 -1022.0
AGO3 -1011.0
INTS5 -1001.0
ZNF562 -962.0
TCEA1 -943.0
ZNF565 -941.0
GPS2 -889.0
PSMC5 -863.0
MED6 -842.0
CD3EAP -835.0
RANBP2 -820.0
SNAPC4 -815.0
TSC2 -804.0
TSN -800.0
FKBP6 -789.0
UBE2I -764.0
BRF2 -745.0
SKIL -725.0
MOBP -714.0
RRAGB -713.0
PCGF6 -689.0
ZNF558 -678.0
CDC27 -651.0
PSMA4 -616.0
NPPA -584.0
MAML2 -582.0
MBD3 -528.0
PABPN1 -526.0
ZNF716 -489.0
TTF1 -328.0
MEF2C -293.0
PPP2R1B -241.0
MED14 -203.0
RRM2 -183.0
ZNF587 -164.0
ZNF200 -154.0
HUS1 -145.0
ZNF222 -84.0
ZNF347 -31.0
ARID4B -27.0
BRD7 -10.0
LEO1 39.0
MT-CO3 40.0
MT-CO2 48.0
KMT2C 63.0
WDR61 77.0
COX16 132.0
WDR5 155.0
KLF4 157.0
UHRF1 170.0
INTS12 172.0
APOE 218.0
MED7 224.0
ABL1 226.0
TCF7L1 275.0
ZNF100 276.0
TRIAP1 281.0
MYB 302.0
CSTF3 309.0
ZNF776 367.0
NFIB 369.0
NELFB 374.0
MLST8 376.0
CSF1R 394.0
POLR2I 396.0
PPP1R13L 399.0
AKT2 433.0
PLAGL1 446.0
CCNB1 467.0
NR3C1 511.0
YY1 537.0
SNAPC1 549.0
COX7C 564.0
CCNA1 585.0
HDAC1 587.0
ELL3 621.0
SNRPE 628.0
CLDN5 650.0
MT-CO1 684.0
BANP 687.0
COX6C 706.0
SETD1B 736.0
INTS1 766.0
NUP62 769.0
CCNH 774.0
KAT6A 794.0
PPARA 813.0
AURKB 846.0
THOC2 911.0
RBBP5 1037.0
ZNF429 1053.0
MAGOH 1054.0
UBA52 1121.0
RPRD1B 1159.0
KMT2B 1179.0
GCK 1193.0
TAF9 1250.0
U2AF1 1287.0
PRKAB1 1302.0
KAT5 1314.0
ITCH 1318.0
ZNF394 1319.0
PRKAA1 1322.0
HSP90AA1 1326.0
ZKSCAN5 1336.0
HDAC9 1359.0
AFF4 1369.0
THRB 1429.0
MED31 1462.0
POU2F1 1537.0
CDK1 1540.0
TPX2 1551.0
PSMD10 1559.0
ATXN3 1601.0
SFN 1615.0
POLR2C 1616.0
ELF1 1630.0
SNRPG 1646.0
SNRPD3 1675.0
CCNA2 1685.0
KCTD15 1758.0
TNFRSF10A 1815.0
PVALB 1839.0
NR1I3 1855.0
CCNC 1877.0
CAMK2G 1921.0
ZNF658B 1948.0
ZNF613 1957.0
CAV1 1969.0
PSMC3 1976.0
PRKAG2 2015.0
MED12 2034.0
CBFB 2078.0
ATF2 2085.0
CNOT11 2102.0
TAF7 2139.0
OPRM1 2161.0
ZKSCAN1 2166.0
CBX4 2222.0
NBN 2267.0
CHM 2273.0
HDAC10 2280.0
GTF2E1 2287.0
STK11 2289.0
MYC 2304.0
SARNP 2436.0
SRSF1 2514.0
PSMB4 2523.0
MED13 2533.0
PSMC2 2598.0
MYBL2 2601.0
ELF2 2606.0
PSMD14 2611.0
DEK 2676.0
GTF2A1 2713.0
SLU7 2727.0
NRBP1 2786.0
SLC38A9 2807.0
POMC 2855.0
E2F8 2856.0
ZNF471 2869.0
CCNK 2877.0
ZNF586 2878.0
SUPT4H1 2890.0
CDC26 2923.0
ZNF770 2964.0
GTF2H2 2984.0
AGO2 2995.0
VENTX 3057.0
NUP37 3074.0
GATAD2A 3075.0
HDAC8 3079.0
MED17 3084.0
RNGTT 3088.0
RAD9B 3090.0
NUP98 3101.0
BTG2 3111.0
DDX21 3113.0
KMT2D 3203.0
HTT 3209.0
MED4 3215.0
THOC6 3225.0
MYO1C 3310.0
SESN2 3311.0
AURKA 3330.0
ZNF445 3333.0
CTR9 3344.0
PSMB1 3374.0
CPSF7 3391.0
CREBBP 3423.0
PSMD5 3426.0
PRDX2 3428.0
PAF1 3478.0
ZNF189 3487.0
NFYA 3506.0
POLR2G 3508.0
RNF2 3513.0
GTF2B 3515.0
RTF1 3526.0
ZNF205 3530.0
SURF1 3532.0
ERCC2 3547.0
SSU72 3574.0
PRMT5 3600.0
AKT1 3614.0
TAF8 3620.0
U2AF2 3663.0
KRAS 3702.0
FAS 3712.0
JUN 3722.0
ZNF668 3725.0
BIRC5 3738.0
ZNF667 3739.0
DPY30 3757.0
SRSF4 3814.0
MAPK11 3826.0
TMEM219 3845.0
NELFE 3860.0
GTF2H5 3874.0
ZNF354A 3889.0
PIWIL4 3916.0
RBX1 3934.0
ZNF747 3949.0
CSNK2B 3969.0
PPARGC1A 3988.0
ZNF333 4007.0
CBX6 4033.0
PSMB2 4084.0
COX4I1 4191.0
CASP1 4224.0
CTSL 4231.0
MAX 4243.0
POU2F2 4251.0
TSNAX 4264.0
SKP1 4287.0
INTS10 4291.0
DNMT3B 4294.0
MDM2 4312.0
SEM1 4348.0
KCTD6 4371.0
SOD2 4390.0
MED26 4395.0
TACO1 4406.0
ING2 4415.0
UBC 4439.0
LAMTOR4 4441.0
COX7B 4465.0
CDKN1A 4511.0
NUP50 4521.0
SUDS3 4526.0
TBL1XR1 4556.0
RPRD1A 4573.0
IPO8 4588.0
PPP2R1A 4589.0
SGK1 4595.0
POLR2F 4604.0
PSMD3 4618.0
NDRG1 4647.0
HDAC3 4673.0
ZNF552 4685.0
ZNF20 4697.0
NOTCH1 4704.0
HDAC5 4710.0
SMARCA4 4733.0
UBE2S 4746.0
ZNF774 4747.0
HDAC11 4756.0
CNOT6 4799.0
DLX6 4817.0
CBX3 4825.0
CRCP 4826.0
ARID1A 4830.0
AR 4840.0
CCNG1 4881.0
ZNF282 4892.0
SMAD2 4905.0
DDIT3 4906.0
RFC2 4948.0
GTF2F1 4951.0
RRAGC 4954.0
CDC25C 4969.0
H2AC20 4972.0
NR2F6 4984.0
SAP18 5004.0
ELL 5009.0
CDC73 5020.0
SNAPC2 5038.0
ZNF775 5041.0
MAPKAP1 5057.0
CTSK 5059.0
COX6A1 5095.0
UBE2C 5101.0
GPRIN1 5131.0
CCNE2 5143.0
TGFB1 5153.0
RAE1 5164.0
SAP30L 5199.0
SNW1 5201.0
CDK7 5211.0
CRADD 5216.0
CASC3 5242.0
NFIX 5243.0
NOTCH2 5272.0
MED16 5278.0
POLR2L 5305.0
H2BC15 5312.0
PTPN11 5314.0
CNOT3 5320.0
SLBP 5337.0
PSMA2 5339.0
H2BC9 5394.0
MAML1 5404.0
ALYREF 5432.0
GTF2F2 5434.0
CBX8 5448.0
FOS 5460.0
USP9X 5464.0
PRKAG1 5476.0
HDAC2 5482.0
TP53BP2 5532.0
EAF1 5533.0
RYBP 5535.0
PBRM1 5566.0
G6PC 5568.0
YWHAZ 5624.0
AGO1 5654.0
COX6B1 5667.0
INTS6 5673.0
PF4 5707.0
PTPN1 5722.0
KDM5B 5736.0
SEC13 5748.0
RNF111 5749.0
PSMD8 5757.0
GTF2E2 5767.0
PRELID1 5790.0
HIPK1 5855.0
NCOR1 5887.0
IWS1 5894.0
BAX 5916.0
ESRRA 5943.0
PSMD13 5948.0
ZNF213 5950.0
THBS1 5951.0
PSMD7 5963.0
PSMA6 5970.0
STEAP3 5996.0
ASH2L 6001.0
ZNF385A 6014.0
BID 6020.0
H2AZ1 6036.0
HIPK2 6078.0
HDAC7 6122.0
EP300 6129.0
IRAK1 6131.0
PDPK1 6136.0
ANAPC11 6161.0
COX5A 6168.0
CTDP1 6180.0
CSNK2A1 6199.0
TIGAR 6204.0
COX5B 6207.0
MED25 6209.0
PSMD11 6231.0
INTS3 6232.0
RRAGA 6244.0
BRCA1 6248.0
NFKB1 6277.0
GP1BA 6279.0
GPI 6284.0
THOC7 6293.0
E2F4 6300.0
USP7 6323.0
LSM10 6338.0
E2F1 6343.0
YWHAB 6385.0
CSNK2A2 6388.0
FOXO4 6391.0
CTNNB1 6408.0
RARA 6429.0
CITED2 6457.0
TP53INP1 6458.0
NDUFA4 6459.0
TAL1 6518.0
SREBF1 6539.0
PSMD12 6556.0
POLR1D 6566.0
MBD2 6581.0
CLP1 6589.0
CPSF3 6602.0
EAF2 6605.0
COX8A 6611.0
CCNG2 6629.0
GSK3B 6634.0
PSMC6 6635.0
UBB 6639.0
PSMF1 6659.0
POLR2J 6671.0
TDG 6672.0
PLK3 6680.0
ZNF230 6689.0
H3C15 6699.5
TWIST2 6721.0
MED20 6743.0
UBE2E1 6759.0
SATB2 6781.0
RRM2B 6798.0
CDC40 6801.0
JUNB 6806.0
PSMB6 6813.0
SUMO1 6889.0
ZNF710 6900.0
SMARCD2 6914.0
RMI1 6947.0
GTF3C6 6962.0
PSMC1 7021.0
PRDX1 7030.0
GTF2A2 7066.0
PSMA7 7096.0
PRKCB 7097.0
TAF10 7110.0
PAPOLA 7153.0
PSMB3 7171.0
ZNF267 7203.0
TAF13 7217.0
THOC5 7235.0
PSMD1 7241.0
JARID2 7243.0
ZNF143 7265.0
POLDIP3 7269.0
EIF4A3 7273.0
H2BC17 7285.0
ELOA 7312.0
PSMA1 7329.0
BCL2L11 7384.0
H2BC4 7389.0
PSMD2 7411.0
NR1H2 7415.0
SRSF9 7422.0
ZFHX3 7425.0
VEGFA 7467.0
ELOB 7482.0
SERPINE1 7483.0
CCND3 7487.0
MAPK1 7493.0
RXRA 7495.0
ELOC 7519.0
RUNX1 7529.0
MED8 7535.0
POLR2E 7563.0
LAMTOR2 7567.0
ZNF746 7573.0
LAMTOR3 7574.0
PSMD9 7620.0
NFYC 7653.0
ITGA5 7659.0
RHEB 7669.0
MYL9 7703.0
PPP2CB 7712.0
COX7A2L 7719.0
PPM1D 7810.0
MLLT1 7825.0
ELL2 7828.0
SMAD6 7835.0
CPSF2 7838.0
CITED4 7844.0
PSMD6 7846.0
NEDD4L 7875.0
TBL1X 7887.0
NOTCH3 7899.0
TET3 7905.0
H2BC11 7912.0
NUP214 7921.0
H2AC6 7934.0
TNFRSF10C 7960.0
TOP3A 7973.0
TAF12 7977.0
NCOR2 7985.0
CEBPB 7997.0
NABP1 8001.0
H2BC5 8003.0
KMT5A 8005.0
NRBF2 8076.0
INTS8 8079.0
TET2 8081.0
PSMB5 8101.0
LBR 8102.0
NFIA 8117.0
TXNRD1 8192.0
SP1 8193.0
PPM1A 8200.0
CNOT8 8227.0
PPP2CA 8234.0
DICER1 8238.0
PSME3 8251.0
TXN 8285.0
SAP30 8303.0
LMO2 8307.0
TNFRSF10B 8321.0
VDR 8348.0
PSMD4 8402.0
GATA1 8410.0
PTEN 8460.0
TFDP1 8470.0
PSMB7 8485.0
NFIC 8486.0
LAMTOR5 8498.0
SMAD1 8511.0
PRDX5 8531.0
NR6A1 8553.0
ARID3A 8584.0
CDK5 8616.0
UBE2D3 8640.0
YWHAH 8649.0
H3-3A 8661.0
SMARCD3 8668.0
FOXO3 8682.0
RB1 8707.0
JAG1 8743.0
LGALS3 8752.0
RRAGD 8753.0
RBPJ 8770.0
NUP58 8820.0
CDKN2B 8836.0
MAP2K6 8887.0
TGFA 8889.0
SPI1 8891.0
ITGA2B 8893.0
PINK1 8941.0
MAPK3 8953.0
MAML3 8957.0
HDAC4 8960.0
ANAPC15 8968.0
TP53I3 8979.0
RETN 8998.0
ZNF697 9002.0
G6PD 9004.0
ACTB 9011.0
APAF1 9015.0
CARM1 9020.0
SLC2A3 9021.0
PHC2 9043.0
YWHAE 9045.0
H2BC12 9051.0
AGO4 9070.0
TNFRSF10D 9072.0
GADD45A 9083.0
FKBP5 9091.0
MAPK14 9104.0
CAT 9123.0
BCL6 9175.0
UBE2D1 9187.0
GSR 9235.0
YWHAG 9264.0
H2BC21 9283.0
BNIP3L 9329.0
H2AJ 9374.0
NLRC4 9406.0
LAMTOR1 9411.0
PRKACA 9429.0
NFE2 9431.0
SOCS3 9476.0
CR1 9486.0
TDRD9 9519.0
PPARG 9522.0


RHO GTPases Activate WASPs and WAVEs

RHO GTPases Activate WASPs and WAVEs
889
set RHO GTPases Activate WASPs and WAVEs
setSize 35
pANOVA 4.57e-10
s.dist 0.609
p.adjustANOVA 1.33e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
WASF1 9520
GRB2 9304
CYFIP1 9265
ARPC1B 9259
ACTB 9011
MAPK3 8953
ARPC1A 8894
RAC1 8793
ARPC5 8686
ACTG1 8562
WAS 8560
WASF2 8369
ARPC3 8277
ACTR2 7870
ACTR3 7818
NCKAP1L 7673
CDC42 7537
ARPC4 7516
MAPK1 7493
NCKAP1 7462

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
WASF1 9520
GRB2 9304
CYFIP1 9265
ARPC1B 9259
ACTB 9011
MAPK3 8953
ARPC1A 8894
RAC1 8793
ARPC5 8686
ACTG1 8562
WAS 8560
WASF2 8369
ARPC3 8277
ACTR2 7870
ACTR3 7818
NCKAP1L 7673
CDC42 7537
ARPC4 7516
MAPK1 7493
NCKAP1 7462
ARPC2 7390
BTK 7206
ABI1 7082
BRK1 7032
WASF3 6808
WIPF2 5713
PTK2 4462
WIPF1 569
NCKIPSD 328
WASL 299
ABL1 226
BAIAP2 -215
CYFIP2 -10367
ABI2 -10915
NCK1 -11454


Intra-Golgi and retrograde Golgi-to-ER traffic

Intra-Golgi and retrograde Golgi-to-ER traffic
571
set Intra-Golgi and retrograde Golgi-to-ER traffic
setSize 179
pANOVA 5.04e-10
s.dist 0.269
p.adjustANOVA 1.42e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
PLIN3 9437
ARF4 9191
PLA2G4A 9180
DCTN2 9157
KDELR1 9142
ARF1 9064
RAB1A 9052
CUX1 8986
STX10 8921
GALNT2 8843
NSF 8829
BICD2 8746
TGOLN2 8714
CAPZA2 8597
DCTN4 8387
COPA 8366
RAB1B 8313
KIF3C 8306
KIF5B 8239
VAMP3 8222

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PLIN3 9437
ARF4 9191
PLA2G4A 9180
DCTN2 9157
KDELR1 9142
ARF1 9064
RAB1A 9052
CUX1 8986
STX10 8921
GALNT2 8843
NSF 8829
BICD2 8746
TGOLN2 8714
CAPZA2 8597
DCTN4 8387
COPA 8366
RAB1B 8313
KIF3C 8306
KIF5B 8239
VAMP3 8222
KIF1B 8184
RAB6A 8148
CAPZA1 8135
CAPZB 8015
TMED7 7950
MAN1A1 7927
STX6 7906
COPB2 7902
ARF5 7885
RAB18 7801
KIF1C 7799
DYNC1I2 7735
ARF3 7732
KDELR2 7728
ACTR10 7605
COPG2 7594
VPS54 7568
COPG1 7509
NAA38 7435
KLC3 7377
COPB1 7321
DCTN6 7300
RAB33B 7267
TMED9 7167
STX5 7166
IGF2R 7149
RAB39A 7113
SURF4 7058
ACTR1A 7002
PAFAH1B2 6942
DYNC1LI1 6941
COPE 6896
RIC1 6824
MAN2A2 6625
GALNT1 6508
RAB43 6433
SNAP29 6390
CYTH4 6085
RAB6B 6053
TMED2 6052
KIF13B 5998
DCTN3 5994
DYNLL1 5952
SEC22B 5873
RAB3GAP1 5768
RAB36 5636
ARCN1 5580
KLC1 5523
KIF23 5510
PAFAH1B1 5470
GOLGA5 5322
VTI1A 5302
GOLIM4 5271
YKT6 5205
KIF20A 5096
DCTN1 5078
AGPAT3 4809
STX18 4648
RGP1 4538
RABEPK 4434
USP6NL 4433
RAB3GAP2 4429
PAFAH1B3 4417
DYNC1LI2 4273
COG7 4269
KIF9 4253
DYNC1I1 4187
NAPG 4139
RAB9A 4088
COPZ1 4035
KIF3B 3740
STX16 3717
ARFGAP3 3714
KIF4A 3585
VAMP4 3191
RACGAP1 2848
KIF16B 2785
GCC1 2730
TMED3 2720
KIF27 2549
TMF1 2535
VPS45 2496
GOLGA1 2415
NAPA 1432
KIF6 1147
USE1 938
KIF11 787
KIF2C 726
CYTH2 442
SYS1 386
CENPE 332
TMED10 323
NBAS 208
ZW10 31
COG4 -6
KIF18B -143
GOSR1 -182
KIFC1 -249
VPS53 -341
COG8 -346
TRIP11 -579
SCOC -885
KIF2A -1069
MAN2A1 -1349
GOSR2 -1456
KIFC2 -1642
ARFGAP1 -1942
MAN1A2 -2055
KDELR3 -2117
KIF18A -2742
NAPB -2780
ARFIP2 -3197
KIF15 -3249
COG5 -3259
VPS52 -3619
RAB41 -3974
DYNLL2 -3980
GOLGA4 -4064
DCTN5 -4086
GBF1 -4290
KIF26A -4925
ARL1 -5063
COG3 -5426
ARFGAP2 -5786
COG6 -5811
RAB9B -6552
VPS51 -6584
KIF21B -6702
KIF28P -6770
MAN1C1 -6804
BICD1 -7365
BET1L -7405
ARFRP1 -7561
BNIP1 -7588
DYNC1H1 -7685
GCC2 -7725
KIF20B -7822
COG2 -7917
CYTH3 -8200
KLC4 -8376
M6PR -8519
KIFAP3 -8619
KIF5C -8865
KIF5A -8869
KLC2 -9059
NAA30 -9696
RAB30 -9844
RINT1 -10112
COPZ2 -10863
RHOBTB3 -11172
NAA35 -11524
KIF26B -11663
KIF19 -11733
KIF21A -11837
KIF3A -11972
PLA2G6 -12122
COG1 -12125
CYTH1 -12314
KIF22 -12358


MyD88 cascade initiated on plasma membrane

MyD88 cascade initiated on plasma membrane
685
set MyD88 cascade initiated on plasma membrane
setSize 82
pANOVA 5.31e-10
s.dist 0.397
p.adjustANOVA 1.42e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
DUSP3 9280
TLR5 9201
APP 9177
MAPK14 9104
MAP2K1 9063
MAPK3 8953
MAP2K6 8887
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966
PELI3 7716
PPP2CB 7712
RPS6KA1 7695

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
DUSP3 9280
TLR5 9201
APP 9177
MAPK14 9104
MAP2K1 9063
MAPK3 8953
MAP2K6 8887
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966
PELI3 7716
PPP2CB 7712
RPS6KA1 7695
MAPK1 7493
TAB2 6964
MAP2K4 6866
NFKBIA 6807
PELI1 6715
UBB 6639
NFKB1 6277
FBXW11 6196
MAP3K8 6160
IRAK1 6131
ATF1 5706
TAB1 5681
UBE2V1 5637
TNIP2 5552
FOS 5460
IKBKG 5377
MAP3K1 5121
ECSIT 4918
PPP2R1A 4589
UBC 4439
DUSP6 4357
MAPK10 4325
SKP1 4287
MAPKAPK2 4054
MAPK11 3826
JUN 3722
TAB3 3160
RPS6KA2 3087
RPS6KA3 2973
PPP2R5D 2421
MAP3K7 2395
ATF2 2085
UBE2N 1936
MAP2K7 1654
AGER 1294
VRK3 1281
UBA52 1121
ELK1 1040
RIPK2 1025
NKIRAS1 375
NFKBIB -152
TRAF6 -229
PPP2R1B -241
HMGB1 -252
MEF2C -293
NFKB2 -1165
MAPK7 -1337
CREB1 -1378
RELA -1803
TLR10 -2961
DUSP7 -3211
BTRC -4924
IKBKB -5386
S100B -5457
DUSP4 -6287
RPS27A -6938
MAPK9 -7068
MAPK8 -9428
IRAK2 -9548
CUL1 -11330
RPS6KA5 -11594
NOD1 -12263


Toll Like Receptor 10 (TLR10) Cascade

Toll Like Receptor 10 (TLR10) Cascade
1236
set Toll Like Receptor 10 (TLR10) Cascade
setSize 82
pANOVA 5.31e-10
s.dist 0.397
p.adjustANOVA 1.42e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
DUSP3 9280
TLR5 9201
APP 9177
MAPK14 9104
MAP2K1 9063
MAPK3 8953
MAP2K6 8887
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966
PELI3 7716
PPP2CB 7712
RPS6KA1 7695

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
DUSP3 9280
TLR5 9201
APP 9177
MAPK14 9104
MAP2K1 9063
MAPK3 8953
MAP2K6 8887
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966
PELI3 7716
PPP2CB 7712
RPS6KA1 7695
MAPK1 7493
TAB2 6964
MAP2K4 6866
NFKBIA 6807
PELI1 6715
UBB 6639
NFKB1 6277
FBXW11 6196
MAP3K8 6160
IRAK1 6131
ATF1 5706
TAB1 5681
UBE2V1 5637
TNIP2 5552
FOS 5460
IKBKG 5377
MAP3K1 5121
ECSIT 4918
PPP2R1A 4589
UBC 4439
DUSP6 4357
MAPK10 4325
SKP1 4287
MAPKAPK2 4054
MAPK11 3826
JUN 3722
TAB3 3160
RPS6KA2 3087
RPS6KA3 2973
PPP2R5D 2421
MAP3K7 2395
ATF2 2085
UBE2N 1936
MAP2K7 1654
AGER 1294
VRK3 1281
UBA52 1121
ELK1 1040
RIPK2 1025
NKIRAS1 375
NFKBIB -152
TRAF6 -229
PPP2R1B -241
HMGB1 -252
MEF2C -293
NFKB2 -1165
MAPK7 -1337
CREB1 -1378
RELA -1803
TLR10 -2961
DUSP7 -3211
BTRC -4924
IKBKB -5386
S100B -5457
DUSP4 -6287
RPS27A -6938
MAPK9 -7068
MAPK8 -9428
IRAK2 -9548
CUL1 -11330
RPS6KA5 -11594
NOD1 -12263


Toll Like Receptor 5 (TLR5) Cascade

Toll Like Receptor 5 (TLR5) Cascade
1240
set Toll Like Receptor 5 (TLR5) Cascade
setSize 82
pANOVA 5.31e-10
s.dist 0.397
p.adjustANOVA 1.42e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
DUSP3 9280
TLR5 9201
APP 9177
MAPK14 9104
MAP2K1 9063
MAPK3 8953
MAP2K6 8887
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966
PELI3 7716
PPP2CB 7712
RPS6KA1 7695

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
DUSP3 9280
TLR5 9201
APP 9177
MAPK14 9104
MAP2K1 9063
MAPK3 8953
MAP2K6 8887
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PELI2 8314
PPP2CA 8234
MYD88 8136
MEF2A 8009
CHUK 7966
PELI3 7716
PPP2CB 7712
RPS6KA1 7695
MAPK1 7493
TAB2 6964
MAP2K4 6866
NFKBIA 6807
PELI1 6715
UBB 6639
NFKB1 6277
FBXW11 6196
MAP3K8 6160
IRAK1 6131
ATF1 5706
TAB1 5681
UBE2V1 5637
TNIP2 5552
FOS 5460
IKBKG 5377
MAP3K1 5121
ECSIT 4918
PPP2R1A 4589
UBC 4439
DUSP6 4357
MAPK10 4325
SKP1 4287
MAPKAPK2 4054
MAPK11 3826
JUN 3722
TAB3 3160
RPS6KA2 3087
RPS6KA3 2973
PPP2R5D 2421
MAP3K7 2395
ATF2 2085
UBE2N 1936
MAP2K7 1654
AGER 1294
VRK3 1281
UBA52 1121
ELK1 1040
RIPK2 1025
NKIRAS1 375
NFKBIB -152
TRAF6 -229
PPP2R1B -241
HMGB1 -252
MEF2C -293
NFKB2 -1165
MAPK7 -1337
CREB1 -1378
RELA -1803
TLR10 -2961
DUSP7 -3211
BTRC -4924
IKBKB -5386
S100B -5457
DUSP4 -6287
RPS27A -6938
MAPK9 -7068
MAPK8 -9428
IRAK2 -9548
CUL1 -11330
RPS6KA5 -11594
NOD1 -12263


Developmental Biology

Developmental Biology
281
set Developmental Biology
setSize 732
pANOVA 1.07e-09
s.dist 0.132
p.adjustANOVA 2.8e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
PPARG 9522
CD36 9444
GRB10 9439
PRKACA 9429
NUMB 9414
LAMC1 9387
H2AJ 9374
ST14 9372
CTNNA1 9341
SDCBP 9311
ARHGEF11 9305
GRB2 9304
ITSN1 9289
DSC2 9288
H2BC21 9283
ARPC1B 9259
FES 9237
ALCAM 9230
NCSTN 9186
PLXNC1 9160

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PPARG 9522.0
CD36 9444.0
GRB10 9439.0
PRKACA 9429.0
NUMB 9414.0
LAMC1 9387.0
H2AJ 9374.0
ST14 9372.0
CTNNA1 9341.0
SDCBP 9311.0
ARHGEF11 9305.0
GRB2 9304.0
ITSN1 9289.0
DSC2 9288.0
H2BC21 9283.0
ARPC1B 9259.0
FES 9237.0
ALCAM 9230.0
NCSTN 9186.0
PLXNC1 9160.0
SPTB 9154.0
ACVR1B 9135.0
ZNF467 9118.0
MAPK14 9104.0
FURIN 9075.0
MAP2K1 9063.0
SEMA4A 9060.0
H2BC12 9051.0
CSTA 9039.0
PIK3CB 9038.0
RAP1GAP 9037.0
CARM1 9020.0
ACTB 9011.0
DLG4 9007.0
CLTC 9000.0
CLTCL1 8965.0
MAML3 8957.0
MAPK3 8953.0
MYO10 8918.0
PLXNB3 8915.0
PDLIM7 8911.0
ARPC1A 8894.0
ITGA2B 8893.0
SPI1 8891.0
MAP2K6 8887.0
CEBPD 8816.0
RAC1 8793.0
ADAM10 8791.0
ANK1 8771.0
RBPJ 8770.0
PCSK6 8740.0
ITGA1 8729.0
CSF3R 8687.0
ARPC5 8686.0
FOXO3 8682.0
SMARCD3 8668.0
H3-3A 8661.0
AP2M1 8627.0
BNIP2 8621.0
CDK5 8616.0
SIAH2 8578.0
MYL6 8576.0
IRS2 8569.0
CAPN1 8563.0
ACTG1 8562.0
NR6A1 8553.0
TLN1 8525.0
PSMB7 8485.0
EPHB3 8479.0
TFDP1 8470.0
PSMD4 8402.0
UNC5A 8399.0
CLTA 8376.0
ABLIM3 8354.0
RHOA 8319.0
SOS2 8299.0
CEBPA 8296.0
ITGB3 8291.0
ARPC3 8277.0
PSME3 8251.0
ST8SIA4 8236.0
PAK1 8230.0
CFL1 8186.0
PAK2 8185.0
DPYSL2 8145.0
IL6R 8132.0
CAP1 8111.0
PSMB5 8101.0
GAB2 8099.0
STAT3 8098.0
HMGCR 8094.0
LIMK2 8074.0
SHTN1 8040.0
EIF4G1 8031.0
VASP 8027.0
AP2S1 8026.0
DOK1 8022.0
RDX 8021.0
MEF2A 8009.0
H2BC5 8003.0
CEBPB 7997.0
MAFB 7991.0
NCOR2 7985.0
PSEN1 7961.0
H2AC6 7934.0
H2BC11 7912.0
TBL1X 7887.0
EPAS1 7886.0
ACTR2 7870.0
PSMD6 7846.0
MPZ 7832.0
ACTR3 7818.0
LYN 7809.0
CAPNS1 7729.0
MYL9 7703.0
RPS6KA1 7695.0
ITGA5 7659.0
PSMD9 7620.0
CDK19 7618.0
SPTA1 7595.0
POLR2E 7563.0
TYROBP 7539.0
CDC42 7537.0
MED8 7535.0
RUNX1 7529.0
ELOC 7519.0
ARPC4 7516.0
RXRA 7495.0
MAPK1 7493.0
ROCK1 7489.0
CCND3 7487.0
ELOB 7482.0
PLXND1 7475.0
ETF1 7419.0
PSMD2 7411.0
ARPC2 7390.0
H2BC4 7389.0
CEBPE 7378.0
PSMA1 7329.0
RGMA 7322.0
DOCK1 7314.0
H2BC17 7285.0
HHEX 7283.0
EIF4A3 7273.0
AP2A2 7257.0
PSMD1 7241.0
RPL26L1 7176.0
PSMB3 7171.0
PSMA7 7096.0
DNM3 7045.0
PSMC1 7021.0
PPP3CB 7005.0
PLXNA2 6977.0
ITGA9 6940.0
MYL12A 6899.0
LYPLA2 6848.0
CYP51A1 6844.0
AP2A1 6832.0
PITPNA 6820.0
PSMB6 6813.0
MAP2K2 6794.0
SRGAP1 6744.0
MED20 6743.0
KRT23 6702.0
H3C15 6699.5
SREBF2 6695.0
MYH9 6685.0
POLR2J 6671.0
PSMF1 6659.0
UBB 6639.0
PSMC6 6635.0
GSK3B 6634.0
PSMD12 6556.0
KAZN 6541.0
SREBF1 6539.0
TAL1 6518.0
GSPT1 6475.0
RARA 6429.0
MYO9B 6424.0
KRT80 6411.0
CTNNB1 6408.0
CSNK2A2 6388.0
E2F1 6343.0
APH1B 6280.0
NFKB1 6277.0
PSMD11 6231.0
MED25 6209.0
CSNK2A1 6199.0
SH3KBP1 6173.0
SRGAP2 6171.0
PRKAR2A 6166.0
LGI2 6163.0
ROCK2 6138.0
EFNA4 6133.0
EP300 6129.0
ITGAV 6106.0
LIPN 6095.0
DNM2 6089.0
CLTB 6084.0
MED13L 6077.0
PIK3CD 6046.0
MEF2B 6041.0
H2AZ1 6036.0
ASH2L 6001.0
PSMA6 5970.0
LAMB1 5966.0
PSMD7 5963.0
PSMD13 5948.0
KRT7 5889.0
NCOR1 5887.0
RANBP9 5813.0
NCOA6 5773.0
PSMD8 5757.0
PSENEN 5735.0
GAB1 5679.0
PKP2 5678.0
SCN1B 5668.0
PLXNB1 5639.0
FLI1 5555.0
MSN 5524.0
HDAC2 5482.0
PFN1 5459.0
RPS9 5421.0
MAML1 5404.0
SDC2 5397.0
H2BC9 5394.0
NRAS 5363.0
PABPC1 5351.0
PSMA2 5339.0
ZSWIM8 5329.0
PTPN11 5314.0
H2BC15 5312.0
POLR2L 5305.0
MED16 5278.0
PAGR1 5276.0
CASC3 5242.0
EPHB4 5203.0
SNW1 5201.0
TGFB1 5153.0
SCN5A 5137.0
COL9A3 5126.0
PBX1 5098.0
MYL12B 5088.0
COL6A3 5053.0
KLF5 5051.0
PIK3R2 5010.0
H2AC20 4972.0
NCK2 4934.0
SMAD2 4905.0
VAV3 4894.0
SPAG9 4803.0
CNOT6 4799.0
SLIT1 4769.0
SMARCA4 4733.0
NOTCH1 4704.0
LIMK1 4679.0
HDAC3 4673.0
PIK3CA 4629.0
PSMD3 4618.0
POLR2F 4604.0
TBL1XR1 4556.0
TSC22D1 4541.0
KRT1 4537.0
CDKN1A 4511.0
RPL3L 4503.0
NCOA1 4483.0
PTK2 4462.0
UBC 4439.0
MED18 4396.0
MED26 4395.0
EPHB2 4355.0
SEM1 4348.0
ABL2 4346.0
PRNP 4250.0
CD24 4185.0
ITGA2 4168.0
SHC1 4161.0
APH1A 4133.0
PSMB2 4084.0
PPARGC1A 3988.0
SHC3 3974.0
CSNK2B 3969.0
RBX1 3934.0
FGF2 3920.0
MAPK13 3865.0
ZNF638 3852.0
MAPK11 3826.0
MED22 3802.0
JUN 3722.0
ADGRV1 3708.0
KRAS 3702.0
KDM6A 3633.0
AKT1 3614.0
DNM1 3587.0
KIF4A 3585.0
CACNA1D 3582.0
RRAS 3575.0
NCOA3 3522.0
POLR2G 3508.0
PSMD5 3426.0
CREBBP 3423.0
PIP5K1C 3419.0
PSMB1 3374.0
MED19 3243.0
MED4 3215.0
KMT2D 3203.0
SCN2A 3185.0
ARHGEF12 3166.0
RPS6KA2 3087.0
MED17 3084.0
PKP4 3044.0
PI3 3023.0
RPS6KA3 2973.0
PSPN 2969.0
EFNA1 2933.0
UNC5B 2809.0
DOK4 2804.0
DEK 2676.0
PSMD14 2611.0
PSMC2 2598.0
LPL 2545.0
MED13 2533.0
CUL2 2526.0
PSMB4 2523.0
ONECUT1 2493.0
KCNQ3 2380.0
MYC 2304.0
PTPRC 2240.0
RASA1 2106.0
CBFB 2078.0
RPS27L 2061.0
NANOG 2038.0
MED12 2034.0
RPS6KA4 1987.0
PSMC3 1976.0
CCNC 1877.0
TRIO 1820.0
POU5F1 1756.0
MMP9 1690.0
PPL 1679.0
POLR2C 1616.0
KRT8 1580.0
PSMD10 1559.0
MED31 1462.0
SCN2B 1401.0
NAB1 1342.0
HSP90AA1 1326.0
RHOB 1254.0
LIN28A 1233.0
RELN 1203.0
GCK 1193.0
PRKCA 1132.0
UBA52 1121.0
NCOA2 1092.0
MAGOH 1054.0
RBBP5 1037.0
KRT10 1031.0
COL4A2 970.0
UPF2 964.0
NFASC 866.0
PPARA 813.0
MYH10 653.0
TIAM1 651.0
YY1 537.0
NTN3 478.0
AKT2 433.0
RPS4Y1 424.0
MSI1 402.0
POLR2I 396.0
THRAP3 388.0
CACNB3 370.0
MYB 302.0
WASL 299.0
SLIT3 296.0
ABL1 226.0
MED7 224.0
EPHB6 175.0
KLF4 157.0
WDR5 155.0
KMT2C 63.0
RPL36AL 32.0
RPLP1 19.0
FAM120B -8.0
CXCR4 -45.0
ITGB1 -94.0
ROBO1 -195.0
MED14 -203.0
RPS24 -263.0
MEF2C -293.0
ITGA10 -322.0
CNTN2 -344.0
FAU -362.0
PRSS8 -364.0
EVPL -473.0
SCN9A -530.0
MED11 -560.0
MAML2 -582.0
CRMP1 -583.0
CLASP1 -588.0
PSMA4 -616.0
USP33 -821.0
MED6 -842.0
PSMC5 -863.0
DOK2 -952.0
RPL15 -963.0
RPLP0 -1000.0
LAMA1 -1044.0
MAPK12 -1074.0
CDK5R1 -1089.0
RPL8 -1187.0
H2AZ2 -1209.0
TCF12 -1233.0
MAPK7 -1337.0
CREB1 -1378.0
MED28 -1429.0
RPS26 -1430.0
EGR2 -1435.0
RPL28 -1462.0
PAK4 -1475.0
KLK14 -1488.0
RND1 -1545.0
DPPA4 -1564.0
COL6A1 -1605.0
RPL22L1 -1619.0
RPS13 -1749.0
POLR2K -1783.0
RELA -1803.0
DSP -1812.0
RBBP4 -1870.0
RPL9 -1872.0
TRPC6 -1935.0
RPL7 -1955.0
CDK8 -1971.0
RPS8 -2083.0
MEIS1 -2102.0
CLASP2 -2151.0
SCN3A -2293.0
PFN2 -2339.0
SUZ12 -2409.0
KAT2B -2414.0
HIF3A -2519.0
POLR2B -2523.0
PKNOX1 -2660.0
ENAH -2707.0
AP2B1 -2709.0
SEMA4D -2830.0
ONECUT3 -2852.0
RPL27 -2855.0
POLR2H -2942.0
STX1B -2952.0
SIAH1 -3000.0
RPL39 -3006.0
PSMB8 -3076.0
POLR2A -3092.0
MEF2D -3094.0
RPL23 -3314.0
RPL6 -3354.0
LGI4 -3358.0
ARHGAP35 -3359.0
HRAS -3382.0
RPL13 -3431.0
FRS2 -3433.0
ANGPTL4 -3469.0
NRCAM -3496.0
MYH11 -3522.0
SPTBN5 -3531.0
RPL4 -3582.0
RPL29 -3611.0
RPL7A -3665.0
RPS15 -3673.0
KALRN -3692.0
COL4A4 -3759.0
PLIN1 -3785.0
TCF4 -3836.0
COL4A3 -3896.0
RPL37A -3946.0
POLR2D -4024.0
MED1 -4036.0
STX1A -4052.0
VAV2 -4055.0
RPS21 -4079.0
PCGF2 -4135.0
PAK3 -4184.0
PRX -4225.0
NRP2 -4282.0
CACNA1I -4311.0
LEFTY1 -4360.0
VLDLR -4385.0
KRT18 -4390.0
RPS2 -4499.0
RPL31 -4541.0
ARHGEF7 -4583.0
CHD9 -4585.0
PTPRA -4626.0
GPC1 -4627.0
NTN1 -4654.0
RPS16 -4669.0
RPS3A -4694.0
RPS28 -4713.0
RPL5 -4728.0
RPL22 -4740.0
RGMB -4805.0
KRT73 -4826.0
SCN8A -4836.0
ANK3 -4919.0
CD72 -4949.0
EBF1 -4954.0
RPS7 -4968.0
CDK2 -5006.0
KRT72 -5021.0
RPL18 -5080.0
EPHA1 -5111.0
CNTNAP1 -5116.0
CHL1 -5122.0
SPTBN2 -5129.0
RARG -5153.0
PSMA3 -5285.0
RPL36 -5287.0
FGFR1 -5352.0
JUP -5353.0
NODAL -5372.0
RPS6KA6 -5394.0
RPL17 -5431.0
TGS1 -5441.0
RPS14 -5463.0
MED30 -5484.0
PMP22 -5556.0
MAMLD1 -5584.0
TGM1 -5651.0
SRGAP3 -5675.0
RPS5 -5691.0
SOS1 -5700.0
SOX10 -5721.0
PSMB10 -5735.0
RPS15A -5742.0
CACNB4 -5768.0
AGAP2 -5788.0
RPS10 -5793.0
RPL24 -5799.0
RPL38 -5840.0
MBP -5848.0
NCBP1 -5853.0
SEMA3A -5854.0
RPS3 -5914.0
MED21 -5937.0
RPS12 -5987.0
CACNB2 -6006.0
RPL35A -6015.0
SCN4A -6037.0
PSMA5 -6053.0
RPL18A -6070.0
PSME4 -6087.0
CDH4 -6111.0
SALL4 -6112.0
WWTR1 -6131.0
RPS6 -6160.0
EFNB2 -6182.0
RPS17 -6247.0
RPL27A -6257.0
RPL11 -6261.0
RPL19 -6281.0
RPS4X -6285.0
RPS23 -6292.0
RPSA -6323.0
DPYSL4 -6331.0
L1CAM -6358.0
RPS25 -6365.0
RPL37 -6375.0
RPL21 -6458.0
RPL10 -6534.0
H2BU1 -6555.0
RPL26 -6612.0
RPL10A -6686.0
RPL32 -6709.0
RPL14 -6710.0
MED23 -6787.0
RPL34 -6802.0
SCN7A -6803.0
SCN3B -6831.0
HSP90AB1 -6863.0
RPL41 -6866.0
DSC1 -6927.0
RPS27A -6938.0
RPS19 -6965.0
RPL30 -7020.0
DRAP1 -7046.0
RPL12 -7053.0
RPLP2 -7087.0
TCF3 -7215.0
ACVR1C -7219.0
RPS11 -7243.0
TNF -7308.0
RPL36A -7376.0
DAG1 -7379.0
MED24 -7387.0
RBM8A -7393.0
LHX4 -7452.0
PIAS2 -7496.0
PSMA8 -7606.0
PSEN2 -7718.0
RPS18 -7744.0
SCD5 -7756.0
SPTBN1 -7764.0
HOXA3 -7794.0
ZNF335 -7813.0
RET -7856.0
AJUBA -7927.0
RPS29 -7940.0
MED29 -7985.0
EFNA3 -8004.0
SEMA6A -8016.0
LEF1 -8076.0
RPL35 -8092.0
DOK6 -8120.0
NTN4 -8121.0
PLXNA3 -8145.0
ARHGAP39 -8166.0
CDON -8176.0
RPL13A -8212.0
HES1 -8266.0
UPF3B -8288.0
SHANK3 -8296.0
DLG1 -8336.0
SMAD4 -8351.0
PLXNA1 -8506.0
RPL3 -8561.0
MED10 -8579.0
FOXP1 -8600.0
CACNG8 -8680.0
GFRA2 -8689.0
PML -8693.0
NRP1 -8717.0
CACNA1H -8721.0
ADAM23 -8734.0
RPL39L -8805.0
KRT15 -8811.0
MED9 -8812.0
SRC -8820.0
RPS20 -8886.0
DAB1 -8895.0
EFNA5 -8908.0
SEMA7A -8986.0
PAXIP1 -8990.0
WNT1 -9014.0
HELZ2 -9045.0
ADAM11 -9112.0
PSMC4 -9127.0
MED27 -9191.0
HOXA1 -9232.0
CTCF -9253.0
MAGOHB -9327.0
TRPC3 -9343.0
EED -9348.0
HOXB2 -9357.0
MAPK8 -9428.0
FOXO1 -9465.0
GIT1 -9471.0
KRTAP5-1 -9478.0
SEMA5A -9495.0
PIK3R1 -9505.0
NCBP2 -9558.0
RPL23A -9567.0
FARP2 -9602.0
TRPC1 -9736.0
EZH2 -9741.0
RPS27 -9756.0
COL9A2 -9770.0
MED15 -9778.0
NEO1 -9779.0
GATA2 -9800.0
UPF3A -9834.0
ABLIM2 -9868.0
LAMA2 -9911.0
WNT10B -9917.0
PERP -9973.0
PSME1 -9991.0
EPHB1 -10082.0
ADGRG6 -10172.0
COL6A2 -10206.0
ARHGEF28 -10288.0
LDB1 -10303.0
ROBO3 -10328.0
PSME2 -10336.0
NAB2 -10400.0
GSPT2 -10403.0
ABLIM1 -10430.0
HOXC4 -10441.0
ACVR2B -10569.0
KMT2A -10725.0
KAT2A -10771.0
EFNB1 -10819.0
CACNB1 -10848.0
CACNA1C -10875.0
HSPA8 -10922.0
HOXB3 -10958.0
NELL2 -11079.0
PLXNA4 -11083.0
PLCG1 -11120.0
ADAM22 -11181.0
HOXB4 -11215.0
CDK4 -11256.0
PSMB9 -11324.0
ACVR2A -11338.0
RHOC -11360.0
SPTAN1 -11426.0
RNPS1 -11427.0
EPHA4 -11431.0
NCK1 -11454.0
PAK6 -11505.0
RPS6KA5 -11594.0
FYN -11675.0
NCAM1 -11706.0
SMAD3 -11745.0
EZR -11769.0
AGRN -11770.0
AKT3 -11849.0
UTRN -11895.0
DLG3 -11922.0
GATA6 -11928.0
PRKACB -11959.0
GFI1 -11968.0
PIK3R3 -12015.0
EOMES -12053.0
PRKCQ -12127.0
YES1 -12142.0
RBBP7 -12155.0
KRT5 -12189.0
EVL -12207.0
ERBB2 -12320.0
AKAP5 -12326.0
EPHA2 -12356.0
TFDP2 -12364.0


Golgi-to-ER retrograde transport

Golgi-to-ER retrograde transport
469
set Golgi-to-ER retrograde transport
setSize 111
pANOVA 1.79e-09
s.dist 0.33
p.adjustANOVA 4.6e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
ARF4 9191
PLA2G4A 9180
DCTN2 9157
KDELR1 9142
ARF1 9064
RAB1A 9052
GALNT2 8843
NSF 8829
BICD2 8746
CAPZA2 8597
DCTN4 8387
COPA 8366
RAB1B 8313
KIF3C 8306
KIF5B 8239
KIF1B 8184
RAB6A 8148
CAPZA1 8135
CAPZB 8015
TMED7 7950

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ARF4 9191
PLA2G4A 9180
DCTN2 9157
KDELR1 9142
ARF1 9064
RAB1A 9052
GALNT2 8843
NSF 8829
BICD2 8746
CAPZA2 8597
DCTN4 8387
COPA 8366
RAB1B 8313
KIF3C 8306
KIF5B 8239
KIF1B 8184
RAB6A 8148
CAPZA1 8135
CAPZB 8015
TMED7 7950
COPB2 7902
ARF5 7885
RAB18 7801
KIF1C 7799
DYNC1I2 7735
ARF3 7732
KDELR2 7728
ACTR10 7605
COPG2 7594
COPG1 7509
KLC3 7377
COPB1 7321
DCTN6 7300
TMED9 7167
SURF4 7058
ACTR1A 7002
PAFAH1B2 6942
DYNC1LI1 6941
COPE 6896
GALNT1 6508
RAB6B 6053
TMED2 6052
KIF13B 5998
DCTN3 5994
DYNLL1 5952
SEC22B 5873
RAB3GAP1 5768
ARCN1 5580
KLC1 5523
KIF23 5510
PAFAH1B1 5470
KIF20A 5096
DCTN1 5078
AGPAT3 4809
STX18 4648
RAB3GAP2 4429
PAFAH1B3 4417
DYNC1LI2 4273
KIF9 4253
DYNC1I1 4187
NAPG 4139
COPZ1 4035
KIF3B 3740
ARFGAP3 3714
KIF4A 3585
RACGAP1 2848
KIF16B 2785
TMED3 2720
KIF27 2549
NAPA 1432
KIF6 1147
USE1 938
KIF11 787
KIF2C 726
CENPE 332
TMED10 323
NBAS 208
ZW10 31
KIF18B -143
KIFC1 -249
KIF2A -1069
KIFC2 -1642
ARFGAP1 -1942
KDELR3 -2117
KIF18A -2742
NAPB -2780
KIF15 -3249
DYNLL2 -3980
DCTN5 -4086
GBF1 -4290
KIF26A -4925
ARFGAP2 -5786
KIF21B -6702
KIF28P -6770
BICD1 -7365
BNIP1 -7588
DYNC1H1 -7685
KIF20B -7822
KLC4 -8376
KIFAP3 -8619
KIF5C -8865
KIF5A -8869
KLC2 -9059
RINT1 -10112
COPZ2 -10863
KIF26B -11663
KIF19 -11733
KIF21A -11837
KIF3A -11972
PLA2G6 -12122
KIF22 -12358


COPI-mediated anterograde transport

COPI-mediated anterograde transport
134
set COPI-mediated anterograde transport
setSize 78
pANOVA 1.9e-09
s.dist 0.393
p.adjustANOVA 4.8e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
ARF4 9191
DCTN2 9157
SPTB 9154
CD55 9145
KDELR1 9142
ARF1 9064
RAB1A 9052
NSF 8829
ANK1 8771
CAPZA2 8597
DCTN4 8387
COPA 8366
RAB1B 8313
CAPZA1 8135
CAPZB 8015
TMED7 7950
COPB2 7902
ARF5 7885
DYNC1I2 7735
ARF3 7732

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ARF4 9191
DCTN2 9157
SPTB 9154
CD55 9145
KDELR1 9142
ARF1 9064
RAB1A 9052
NSF 8829
ANK1 8771
CAPZA2 8597
DCTN4 8387
COPA 8366
RAB1B 8313
CAPZA1 8135
CAPZB 8015
TMED7 7950
COPB2 7902
ARF5 7885
DYNC1I2 7735
ARF3 7732
KDELR2 7728
ACTR10 7605
SPTA1 7595
COPG2 7594
COPG1 7509
COPB1 7321
DCTN6 7300
TMED9 7167
STX5 7166
ACTR1A 7002
DYNC1LI1 6941
COPE 6896
GORASP1 6606
GOLGA2 6203
TMED2 6052
DCTN3 5994
DYNLL1 5952
CD59 5859
ARCN1 5580
TMEM115 5508
YKT6 5205
DCTN1 5078
DYNC1LI2 4273
COG7 4269
DYNC1I1 4187
USO1 4154
NAPG 4139
COPZ1 4035
ARFGAP3 3714
TMED3 2720
NAPA 1432
TMED10 323
COG4 -6
GOSR1 -182
COG8 -346
BET1 -594
GOSR2 -1456
ARFGAP1 -1942
KDELR3 -2117
NAPB -2780
COG5 -3259
SPTBN5 -3531
DYNLL2 -3980
DCTN5 -4086
GBF1 -4290
ANK3 -4919
SPTBN2 -5129
GOLGB1 -5370
COG3 -5426
ARFGAP2 -5786
COG6 -5811
BET1L -7405
DYNC1H1 -7685
SPTBN1 -7764
COG2 -7917
COPZ2 -10863
SPTAN1 -11426
COG1 -12125


Programmed Cell Death

Programmed Cell Death
861
set Programmed Cell Death
setSize 171
pANOVA 2.1e-09
s.dist 0.265
p.adjustANOVA 5.16e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
H1-2 9491
VIM 9394
LMNB1 9345
YWHAG 9264
CD14 9097
YWHAE 9045
TLR4 9016
APAF1 9015
PRKCD 9008
MAPK3 8953
LY96 8795
GSN 8749
BCL2L1 8700
HMGB2 8671
BMX 8664
YWHAH 8649
PSMB7 8485
TFDP1 8470
PSMD4 8402
UNC5A 8399

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H1-2 9491
VIM 9394
LMNB1 9345
YWHAG 9264
CD14 9097
YWHAE 9045
TLR4 9016
APAF1 9015
PRKCD 9008
MAPK3 8953
LY96 8795
GSN 8749
BCL2L1 8700
HMGB2 8671
BMX 8664
YWHAH 8649
PSMB7 8485
TFDP1 8470
PSMD4 8402
UNC5A 8399
TNFRSF10B 8321
PSME3 8251
PAK2 8185
PPP3R1 8175
PSMB5 8101
STAT3 8098
PSMD6 7846
DBNL 7749
CASP9 7685
PSMD9 7620
CFLAR 7610
MAPK1 7493
H1-0 7492
ROCK1 7489
PSMD2 7411
BCL2L11 7384
PSMA1 7329
MLKL 7316
PSMD1 7241
DAPK2 7237
PSMB3 7171
PSMA7 7096
PSMC1 7021
DAPK1 6924
BAD 6892
PSMB6 6813
SEPTIN4 6703
PSMF1 6659
UBB 6639
PSMC6 6635
BCAP31 6565
PSMD12 6556
STK24 6487
CTNNB1 6408
YWHAB 6385
E2F1 6343
TICAM2 6335
TICAM1 6307
PSMD11 6231
BID 6020
PSMA6 5970
PSMD7 5963
DYNLL1 5952
PSMD13 5948
BAX 5916
PSMD8 5757
ADD1 5704
FADD 5641
YWHAZ 5624
TP53BP2 5532
PSMA2 5339
APIP 4962
CARD8 4726
BIRC2 4692
PLEC 4633
PSMD3 4618
DAPK3 4514
PTK2 4462
UBC 4439
BMF 4375
SEM1 4348
NMT1 4328
RIPK3 4217
TJP2 4142
PSMB2 4084
LMNA 3887
FAS 3712
CLSPN 3640
AKT1 3614
PSMD5 3426
PSMB1 3374
DFFA 3371
APC 3240
TNFSF10 3093
DNM1L 3015
OMA1 2947
UNC5B 2809
OPA1 2740
PSMD14 2611
PSMC2 2598
PSMB4 2523
KPNB1 2430
H1-4 2207
UACA 2159
PSMC3 1976
TNFRSF10A 1815
SFN 1615
PSMD10 1559
XIAP 1407
KPNA1 1296
UBA52 1121
ACIN1 862
AKT2 433
APPL1 336
CASP7 55
HMGB1 -252
BAK1 -309
TRADD -556
PSMA4 -616
CASP3 -632
C1QBP -822
PSMC5 -863
CYCS -1334
DSP -1812
OCLN -2327
CASP6 -2831
PSMB8 -3076
DYNLL2 -3980
BCL2 -4704
TP73 -4754
CDKN2A -5236
PSMA3 -5285
MAPT -5437
FNTA -5724
PSMB10 -5735
PSMA5 -6053
PSME4 -6087
TJP1 -6374
DIABLO -6393
DFFB -6836
RPS27A -6938
YWHAQ -7340
PSMA8 -7606
BBC3 -7864
SATB1 -7905
AVEN -8133
GAS2 -8542
ARHGAP10 -8847
PSMC4 -9127
MAPK8 -9428
PSME1 -9991
PSME2 -10336
TP63 -10842
STK26 -10888
TP53 -10893
PMAIP1 -10986
RIPK1 -11074
BIRC3 -11125
PSMB9 -11324
CASP8 -11336
SPTAN1 -11426
CDH1 -11500
PPP1R13B -11636
TRAF2 -11746
AKT3 -11849
PPP3CC -12126
PRKCQ -12127
MAGED1 -12295
GZMB -12361
TFDP2 -12364
FASLG -12371


Autophagy

Autophagy
97
set Autophagy
setSize 124
pANOVA 2.12e-09
s.dist 0.311
p.adjustANOVA 5.16e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
RNASE1 9467
PLIN3 9437
LAMTOR1 9411
MTMR3 9069
HBB 9054
GABARAPL2 9044
PINK1 8941
CHMP4B 8866
LAMP2 8786
CHMP2A 8780
RRAGD 8753
UBAP1 8701
LAMTOR5 8498
CHMP3 8349
ATG3 8293
PLIN2 8261
ATG7 8134
NBR1 8119
MAP1LC3B 8043
MTMR14 8032

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RNASE1 9467
PLIN3 9437
LAMTOR1 9411
MTMR3 9069
HBB 9054
GABARAPL2 9044
PINK1 8941
CHMP4B 8866
LAMP2 8786
CHMP2A 8780
RRAGD 8753
UBAP1 8701
LAMTOR5 8498
CHMP3 8349
ATG3 8293
PLIN2 8261
ATG7 8134
NBR1 8119
MAP1LC3B 8043
MTMR14 8032
VPS37C 8010
GABARAP 7904
EPAS1 7886
TSG101 7786
DYNC1I2 7735
RHEB 7669
LAMTOR3 7574
LAMTOR2 7567
MVB12A 7400
WIPI1 7277
ULK1 7125
MAP1LC3A 7094
DYNC1LI1 6941
VCP 6886
MFN2 6750
GFAP 6713
UBB 6639
BECN1 6516
VPS37A 6467
PARK7 6421
CSNK2A2 6388
RRAGA 6244
CSNK2A1 6199
ATG9A 6067
HSF1 6063
DYNLL1 5952
CHMP2B 5714
UBE2V1 5637
ATG10 5553
CHMP6 5499
PRKAG1 5476
WIPI2 5330
MVB12B 5175
RRAGC 4954
RB1CC1 4946
ATG4C 4607
LAMTOR4 4441
UBC 4439
VDAC1 4347
DYNC1LI2 4273
PEX5 4225
VPS28 4199
DYNC1I1 4187
SQSTM1 4081
CSNK2B 3969
VPS37B 3908
ATG101 3754
TOMM22 3403
WDR45 2925
SLC38A9 2807
CFTR 2416
CHMP4A 2400
TOMM6 2323
PRKAG2 2015
UBE2N 1936
PIK3C3 1619
WDR45B 1590
ATG5 1398
HSP90AA1 1326
PRKAA1 1322
PRKAB1 1302
UBA52 1121
USP30 856
ATG4A 666
ATG13 640
MLST8 376
RRAGB -713
ATG12 -770
TSC2 -804
TOMM5 -1539
TSC1 -2118
IFT88 -2201
GABARAPL1 -2419
TOMM20 -2743
ARL13B -3064
ATG4B -3468
DYNLL2 -3980
PIK3R4 -4062
ATG4D -4386
MFN1 -4966
TOMM7 -4975
EEF1A1 -5087
PGAM5 -5356
FUNDC1 -6036
MTERF3 -6856
HSP90AB1 -6863
RPS27A -6938
DYNC1H1 -7685
TOMM40 -7967
PRKAB2 -8172
AMBRA1 -8186
HDAC6 -8337
TOMM70 -8541
CHMP7 -8802
SRC -8820
UVRAG -9024
MTOR -9767
ATG9B -9906
RPTOR -10464
HSPA8 -10922
ATM -11148
ATG14 -11847
ATG16L1 -11966
PCNT -12169


Apoptosis

Apoptosis
79
set Apoptosis
setSize 168
pANOVA 2.16e-09
s.dist 0.268
p.adjustANOVA 5.16e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
H1-2 9491
VIM 9394
LMNB1 9345
YWHAG 9264
CD14 9097
YWHAE 9045
TLR4 9016
APAF1 9015
PRKCD 9008
MAPK3 8953
LY96 8795
GSN 8749
BCL2L1 8700
HMGB2 8671
BMX 8664
YWHAH 8649
PSMB7 8485
TFDP1 8470
PSMD4 8402
UNC5A 8399

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H1-2 9491
VIM 9394
LMNB1 9345
YWHAG 9264
CD14 9097
YWHAE 9045
TLR4 9016
APAF1 9015
PRKCD 9008
MAPK3 8953
LY96 8795
GSN 8749
BCL2L1 8700
HMGB2 8671
BMX 8664
YWHAH 8649
PSMB7 8485
TFDP1 8470
PSMD4 8402
UNC5A 8399
TNFRSF10B 8321
PSME3 8251
PAK2 8185
PPP3R1 8175
PSMB5 8101
STAT3 8098
PSMD6 7846
DBNL 7749
CASP9 7685
PSMD9 7620
CFLAR 7610
MAPK1 7493
H1-0 7492
ROCK1 7489
PSMD2 7411
BCL2L11 7384
PSMA1 7329
PSMD1 7241
DAPK2 7237
PSMB3 7171
PSMA7 7096
PSMC1 7021
DAPK1 6924
BAD 6892
PSMB6 6813
SEPTIN4 6703
PSMF1 6659
UBB 6639
PSMC6 6635
BCAP31 6565
PSMD12 6556
STK24 6487
CTNNB1 6408
YWHAB 6385
E2F1 6343
TICAM2 6335
TICAM1 6307
PSMD11 6231
BID 6020
PSMA6 5970
PSMD7 5963
DYNLL1 5952
PSMD13 5948
BAX 5916
PSMD8 5757
ADD1 5704
FADD 5641
YWHAZ 5624
TP53BP2 5532
PSMA2 5339
APIP 4962
CARD8 4726
BIRC2 4692
PLEC 4633
PSMD3 4618
DAPK3 4514
PTK2 4462
UBC 4439
BMF 4375
SEM1 4348
NMT1 4328
TJP2 4142
PSMB2 4084
LMNA 3887
FAS 3712
CLSPN 3640
AKT1 3614
PSMD5 3426
PSMB1 3374
DFFA 3371
APC 3240
TNFSF10 3093
DNM1L 3015
OMA1 2947
UNC5B 2809
OPA1 2740
PSMD14 2611
PSMC2 2598
PSMB4 2523
KPNB1 2430
H1-4 2207
UACA 2159
PSMC3 1976
TNFRSF10A 1815
SFN 1615
PSMD10 1559
XIAP 1407
KPNA1 1296
UBA52 1121
ACIN1 862
AKT2 433
APPL1 336
CASP7 55
HMGB1 -252
BAK1 -309
TRADD -556
PSMA4 -616
CASP3 -632
C1QBP -822
PSMC5 -863
CYCS -1334
DSP -1812
OCLN -2327
CASP6 -2831
PSMB8 -3076
DYNLL2 -3980
BCL2 -4704
TP73 -4754
CDKN2A -5236
PSMA3 -5285
MAPT -5437
FNTA -5724
PSMB10 -5735
PSMA5 -6053
PSME4 -6087
TJP1 -6374
DIABLO -6393
DFFB -6836
RPS27A -6938
YWHAQ -7340
PSMA8 -7606
BBC3 -7864
SATB1 -7905
AVEN -8133
GAS2 -8542
ARHGAP10 -8847
PSMC4 -9127
MAPK8 -9428
PSME1 -9991
PSME2 -10336
TP63 -10842
STK26 -10888
TP53 -10893
PMAIP1 -10986
RIPK1 -11074
PSMB9 -11324
CASP8 -11336
SPTAN1 -11426
CDH1 -11500
PPP1R13B -11636
TRAF2 -11746
AKT3 -11849
PPP3CC -12126
PRKCQ -12127
MAGED1 -12295
GZMB -12361
TFDP2 -12364
FASLG -12371


EPH-Ephrin signaling

EPH-Ephrin signaling
322
set EPH-Ephrin signaling
setSize 79
pANOVA 2.31e-09
s.dist 0.389
p.adjustANOVA 5.44e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
SDCBP 9311
ITSN1 9289
ARPC1B 9259
NCSTN 9186
ACTB 9011
CLTC 9000
CLTCL1 8965
ARPC1A 8894
RAC1 8793
ADAM10 8791
ARPC5 8686
AP2M1 8627
MYL6 8576
ACTG1 8562
EPHB3 8479
CLTA 8376
RHOA 8319
ARPC3 8277
PAK1 8230
CFL1 8186

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SDCBP 9311
ITSN1 9289
ARPC1B 9259
NCSTN 9186
ACTB 9011
CLTC 9000
CLTCL1 8965
ARPC1A 8894
RAC1 8793
ADAM10 8791
ARPC5 8686
AP2M1 8627
MYL6 8576
ACTG1 8562
EPHB3 8479
CLTA 8376
RHOA 8319
ARPC3 8277
PAK1 8230
CFL1 8186
PAK2 8185
LIMK2 8074
AP2S1 8026
PSEN1 7961
ACTR2 7870
ACTR3 7818
LYN 7809
MYL9 7703
CDC42 7537
ARPC4 7516
ROCK1 7489
ARPC2 7390
AP2A2 7257
MYL12A 6899
AP2A1 6832
MYH9 6685
APH1B 6280
ROCK2 6138
EFNA4 6133
CLTB 6084
PSENEN 5735
SDC2 5397
EPHB4 5203
MYL12B 5088
NCK2 4934
VAV3 4894
LIMK1 4679
PTK2 4462
EPHB2 4355
APH1A 4133
DNM1 3587
EFNA1 2933
RASA1 2106
MMP9 1690
MYH10 653
TIAM1 651
WASL 299
EPHB6 175
AP2B1 -2709
HRAS -3382
MYH11 -3522
KALRN -3692
VAV2 -4055
PAK3 -4184
ARHGEF7 -4583
EPHA1 -5111
EFNB2 -6182
PSEN2 -7718
EFNA3 -8004
SRC -8820
EFNA5 -8908
GIT1 -9471
EPHB1 -10082
ARHGEF28 -10288
EFNB1 -10819
EPHA4 -11431
FYN -11675
YES1 -12142
EPHA2 -12356


Amyloid fiber formation

Amyloid fiber formation
70
set Amyloid fiber formation
setSize 51
pANOVA 2.44e-09
s.dist 0.483
p.adjustANOVA 5.64e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
SNCA 9354.0
H2BC21 9283.0
NCSTN 9186.0
APP 9177.0
FURIN 9075.0
H2BC12 9051.0
ADAM10 8791.0
GSN 8749.0
H3-3A 8661.0
SIAH2 8578.0
TGFBI 8211.0
H2BC5 8003.0
H2AC6 7934.0
H2BC11 7912.0
H2BC4 7389.0
H2BC17 7285.0
LYZ 7213.0
TSPAN14 6971.0
H3C15 6699.5
UBB 6639.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SNCA 9354.0
H2BC21 9283.0
NCSTN 9186.0
APP 9177.0
FURIN 9075.0
H2BC12 9051.0
ADAM10 8791.0
GSN 8749.0
H3-3A 8661.0
SIAH2 8578.0
TGFBI 8211.0
H2BC5 8003.0
H2AC6 7934.0
H2BC11 7912.0
H2BC4 7389.0
H2BC17 7285.0
LYZ 7213.0
TSPAN14 6971.0
H3C15 6699.5
UBB 6639.0
SORL1 6530.0
LTF 6306.0
APH1B 6280.0
TSPAN33 6170.0
H2AZ1 6036.0
ITM2B 5982.0
PSENEN 5735.0
USP9X 5464.0
H2BC9 5394.0
H2BC15 5312.0
H2AC20 4972.0
UBC 4439.0
APH1A 4133.0
GGA3 3816.0
BACE1 3609.0
MFGE8 3534.0
GGA1 2310.0
CST3 2206.0
UBA52 1121.0
TSPAN5 1028.0
NPPA -584.0
TSPAN15 -1876.0
CALB1 -2832.0
SIAH1 -3000.0
NAT8B -3939.0
H2BU1 -6555.0
GGA2 -6587.0
B2M -6920.0
RPS27A -6938.0
HSPG2 -7779.0
UBE2L6 -11293.0


Signaling by WNT

Signaling by WNT
1139
set Signaling by WNT
setSize 254
pANOVA 4.05e-09
s.dist 0.214
p.adjustANOVA 9.21e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
FZD5 9513
H2AJ 9374
GNG10 9349
SNX3 9326
H2BC21 9283
WNT11 9215
KREMEN1 9149
FRAT2 9096
AGO4 9070
H2BC12 9051
CLTC 9000
PLCB3 8916
GNG5 8815
RAC1 8793
FRAT1 8712
RNF146 8696
H3-3A 8661
AP2M1 8627
TLE3 8558
ARRB2 8490

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FZD5 9513.0
H2AJ 9374.0
GNG10 9349.0
SNX3 9326.0
H2BC21 9283.0
WNT11 9215.0
KREMEN1 9149.0
FRAT2 9096.0
AGO4 9070.0
H2BC12 9051.0
CLTC 9000.0
PLCB3 8916.0
GNG5 8815.0
RAC1 8793.0
FRAT1 8712.0
RNF146 8696.0
H3-3A 8661.0
AP2M1 8627.0
TLE3 8558.0
ARRB2 8490.0
PSMB7 8485.0
PSMD4 8402.0
CLTA 8376.0
RHOA 8319.0
GNB1 8294.0
PSME3 8251.0
PPP2CA 8234.0
PPP3R1 8175.0
GNB2 8141.0
WLS 8104.0
PSMB5 8101.0
AP2S1 8026.0
H2BC5 8003.0
H2AC6 7934.0
H2BC11 7912.0
PSMD6 7846.0
CSNK1A1 7766.0
PPP2CB 7712.0
PSMD9 7620.0
CTNNBIP1 7569.0
KLHL12 7429.0
PSMD2 7411.0
H2BC4 7389.0
GNB4 7336.0
PSMA1 7329.0
H2BC17 7285.0
AP2A2 7257.0
PSMD1 7241.0
PSMB3 7171.0
PRKCB 7097.0
PSMA7 7096.0
PSMC1 7021.0
PPP3CB 7005.0
TMED5 6984.0
PRKG1 6901.0
TLE4 6854.0
AP2A1 6832.0
CUL3 6821.0
PSMB6 6813.0
PPP2R5B 6774.0
H3C15 6699.5
GNAT2 6683.0
VPS35 6668.0
PSMF1 6659.0
UBB 6639.0
PSMC6 6635.0
GSK3B 6634.0
VPS26A 6632.0
PSMD12 6556.0
GNG11 6495.0
FZD2 6462.0
PIP5K1B 6450.0
USP8 6418.0
CTNNB1 6408.0
CSNK2A2 6388.0
PSMD11 6231.0
PPP3CA 6217.0
CSNK2A1 6199.0
EP300 6129.0
CLTB 6084.0
H2AZ1 6036.0
ASH2L 6001.0
PSMA6 5970.0
PSMD7 5963.0
PSMD13 5948.0
PPP2R5A 5897.0
ITPR2 5842.0
PSMD8 5757.0
SOX6 5665.0
DVL3 5656.0
AGO1 5654.0
YWHAZ 5624.0
PFN1 5459.0
H2BC9 5394.0
PSMA2 5339.0
H2BC15 5312.0
RAC2 5163.0
CDC73 5020.0
H2AC20 4972.0
WNT6 4864.0
SOX4 4850.0
SMARCA4 4733.0
PLCB2 4665.0
PSMD3 4618.0
PPP2R1A 4589.0
FZD1 4492.0
UBC 4439.0
SEM1 4348.0
GNG8 4296.0
LRP5 4289.0
SKP1 4287.0
PSMB2 4084.0
CTBP2 4080.0
CSNK2B 3969.0
RBX1 3934.0
ZRANB1 3730.0
KRAS 3702.0
AKT1 3614.0
DAAM1 3466.0
PSMD5 3426.0
CREBBP 3423.0
NLK 3405.0
PSMB1 3374.0
APC 3240.0
KMT2D 3203.0
VPS29 3151.0
AGO2 2995.0
LGR4 2883.0
PSMD14 2611.0
PSMC2 2598.0
PSMB4 2523.0
PPP2R5D 2421.0
MAP3K7 2395.0
MYC 2304.0
PRICKLE1 2283.0
WNT9B 1992.0
PSMC3 1976.0
CAV1 1969.0
PSMD10 1559.0
XIAP 1407.0
TERT 1341.0
KAT5 1314.0
DACT1 1252.0
PLCB1 1197.0
PRKCA 1132.0
UBA52 1121.0
RBBP5 1037.0
GNG3 890.0
CSNK1G2 887.0
CHD8 604.0
HDAC1 587.0
LRP6 577.0
GNB5 512.0
AKT2 433.0
KREMEN2 316.0
TCF7L1 275.0
LEO1 39.0
DVL1 0.0
WNT5B -61.0
PARD6A -239.0
PPP2R1B -241.0
TNKS2 -499.0
PSMA4 -616.0
PPP2R5E -680.0
PSMC5 -863.0
USP34 -944.0
AGO3 -1011.0
XPO1 -1185.0
PDE6G -1189.0
BCL9 -1190.0
H2AZ2 -1209.0
ZNRF3 -1963.0
CALM1 -2081.0
GNG4 -2154.0
PDE6A -2204.0
ROR1 -2376.0
GNB3 -2397.0
SMURF1 -2591.0
SOX7 -2675.0
AP2B1 -2709.0
WNT8B -2841.0
SCRIB -2849.0
PSMB8 -3076.0
RAC3 -3262.0
TCF4 -3836.0
WNT2B -3938.0
WNT9A -4397.0
WNT4 -4485.0
TNRC6B -4518.0
WNT3 -4684.0
WNT16 -4921.0
BTRC -4924.0
GNG7 -5198.0
PSMA3 -5285.0
TNRC6A -5613.0
PSMB10 -5735.0
PSMA5 -6053.0
PSME4 -6087.0
TCF7L2 -6185.0
CTBP1 -6456.0
FZD7 -6508.0
FZD6 -6525.0
H2BU1 -6555.0
TRRAP -6722.0
RPS27A -6938.0
TLE1 -6942.0
FZD8 -7138.0
FZD3 -7186.0
TLE2 -7449.0
PSMA8 -7606.0
ITPR1 -7629.0
GNG2 -7795.0
WNT7A -7966.0
LEF1 -8076.0
CXXC4 -8078.0
AXIN2 -8154.0
PRKG2 -8477.0
MEN1 -8538.0
RUVBL1 -8612.0
TNKS -8738.0
WNT1 -9014.0
PSMC4 -9127.0
NFATC1 -9147.0
RYK -9346.0
WNT10A -9848.0
WNT10B -9917.0
GNAO1 -9936.0
PSME1 -9991.0
PORCN -10074.0
CBY1 -10077.0
TCF7 -10173.0
AXIN1 -10285.0
CSNK1E -10298.0
ITPR3 -10308.0
PSME2 -10336.0
SMURF2 -10340.0
DVL2 -11152.0
PPP2R5C -11265.0
SOX13 -11280.0
AMER1 -11301.0
PSMB9 -11324.0
PYGO2 -11326.0
CUL1 -11330.0
PDE6B -11387.0
FZD4 -11650.0
TNRC6C -11828.0
TLE5 -11957.0
BCL9L -11981.0
MOV10 -11991.0
CCDC88C -12041.0
GNGT2 -12086.0
RNF43 -12121.0
LGR6 -12286.0
RUNX3 -12352.0


RHO GTPases activate PKNs

RHO GTPases activate PKNs
894
set RHO GTPases activate PKNs
setSize 48
pANOVA 6.95e-09
s.dist 0.483
p.adjustANOVA 1.56e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2AJ 9374.0
H2BC21 9283.0
YWHAG 9264.0
H2BC12 9051.0
YWHAE 9045.0
RAC1 8793.0
H3-3A 8661.0
YWHAH 8649.0
MYL6 8576.0
RHOA 8319.0
PAK1 8230.0
H2BC5 8003.0
H2AC6 7934.0
H2BC11 7912.0
MYL9 7703.0
H2BC4 7389.0
H2BC17 7285.0
PPP1CB 7064.0
PPP1R14A 6839.0
H3C15 6699.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2AJ 9374.0
H2BC21 9283.0
YWHAG 9264.0
H2BC12 9051.0
YWHAE 9045.0
RAC1 8793.0
H3-3A 8661.0
YWHAH 8649.0
MYL6 8576.0
RHOA 8319.0
PAK1 8230.0
H2BC5 8003.0
H2AC6 7934.0
H2BC11 7912.0
MYL9 7703.0
H2BC4 7389.0
H2BC17 7285.0
PPP1CB 7064.0
PPP1R14A 6839.0
H3C15 6699.5
MYH9 6685.0
YWHAB 6385.0
PDPK1 6136.0
PPP1R12A 6050.0
H2AZ1 6036.0
YWHAZ 5624.0
H2BC9 5394.0
H2BC15 5312.0
MYL12B 5088.0
H2AC20 4972.0
CDC25C 4969.0
AR 4840.0
KLK2 3029.0
PPP1R12B 1775.0
SFN 1615.0
RHOB 1254.0
NCOA2 1092.0
MYH10 653.0
PKN2 98.0
H2AZ2 -1209.0
PKN1 -2208.0
MYH11 -3522.0
PKN3 -3793.0
H2BU1 -6555.0
YWHAQ -7340.0
KDM1A -9430.0
KDM4C -10749.0
RHOC -11360.0


MyD88-independent TLR4 cascade

MyD88-independent TLR4 cascade
688
set MyD88-independent TLR4 cascade
setSize 96
pANOVA 7.99e-09
s.dist 0.341
p.adjustANOVA 1.73e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
DUSP3 9280
UBE2D1 9187
APP 9177
MAPK14 9104
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
MAP2K6 8887
LY96 8795
MAP2K3 8748
UBE2D3 8640
NOD2 8442
MAPKAPK3 8382
PPP2CA 8234
MEF2A 8009
CHUK 7966
PPP2CB 7712

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
DUSP3 9280
UBE2D1 9187
APP 9177
MAPK14 9104
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
MAP2K6 8887
LY96 8795
MAP2K3 8748
UBE2D3 8640
NOD2 8442
MAPKAPK3 8382
PPP2CA 8234
MEF2A 8009
CHUK 7966
PPP2CB 7712
RPS6KA1 7695
TANK 7502
MAPK1 7493
TAB2 6964
MAP2K4 6866
NFKBIA 6807
UBB 6639
TICAM2 6335
TICAM1 6307
NFKB1 6277
FBXW11 6196
MAP3K8 6160
IRAK1 6131
ATF1 5706
TAB1 5681
FADD 5641
UBE2V1 5637
TNIP2 5552
FOS 5460
IKBKG 5377
PTPN11 5314
IKBKE 4715
BIRC2 4692
UBE2D2 4657
PPP2R1A 4589
UBC 4439
DUSP6 4357
MAPK10 4325
SKP1 4287
RIPK3 4217
MAPKAPK2 4054
MAPK11 3826
JUN 3722
TBK1 3229
TAB3 3160
RPS6KA2 3087
RPS6KA3 2973
PPP2R5D 2421
MAP3K7 2395
ATF2 2085
UBE2N 1936
MAP2K7 1654
AGER 1294
VRK3 1281
UBA52 1121
ELK1 1040
RIPK2 1025
NKIRAS1 375
NFKBIB -152
TRAF6 -229
PPP2R1B -241
HMGB1 -252
MEF2C -293
NFKB2 -1165
MAPK7 -1337
CREB1 -1378
RELA -1803
DUSP7 -3211
BTRC -4924
IKBKB -5386
S100B -5457
TRAF3 -5576
DUSP4 -6287
RPS27A -6938
MAPK9 -7068
IRF3 -8517
IRF7 -8657
MAPK8 -9428
IRAK2 -9548
RIPK1 -11074
BIRC3 -11125
CUL1 -11330
CASP8 -11336
RPS6KA5 -11594
SARM1 -12134
NOD1 -12263


TRIF(TICAM1)-mediated TLR4 signaling

TRIF(TICAM1)-mediated TLR4 signaling
1215
set TRIF(TICAM1)-mediated TLR4 signaling
setSize 96
pANOVA 7.99e-09
s.dist 0.341
p.adjustANOVA 1.73e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
DUSP3 9280
UBE2D1 9187
APP 9177
MAPK14 9104
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
MAP2K6 8887
LY96 8795
MAP2K3 8748
UBE2D3 8640
NOD2 8442
MAPKAPK3 8382
PPP2CA 8234
MEF2A 8009
CHUK 7966
PPP2CB 7712

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
DUSP3 9280
UBE2D1 9187
APP 9177
MAPK14 9104
CD14 9097
MAP2K1 9063
TLR4 9016
MAPK3 8953
MAP2K6 8887
LY96 8795
MAP2K3 8748
UBE2D3 8640
NOD2 8442
MAPKAPK3 8382
PPP2CA 8234
MEF2A 8009
CHUK 7966
PPP2CB 7712
RPS6KA1 7695
TANK 7502
MAPK1 7493
TAB2 6964
MAP2K4 6866
NFKBIA 6807
UBB 6639
TICAM2 6335
TICAM1 6307
NFKB1 6277
FBXW11 6196
MAP3K8 6160
IRAK1 6131
ATF1 5706
TAB1 5681
FADD 5641
UBE2V1 5637
TNIP2 5552
FOS 5460
IKBKG 5377
PTPN11 5314
IKBKE 4715
BIRC2 4692
UBE2D2 4657
PPP2R1A 4589
UBC 4439
DUSP6 4357
MAPK10 4325
SKP1 4287
RIPK3 4217
MAPKAPK2 4054
MAPK11 3826
JUN 3722
TBK1 3229
TAB3 3160
RPS6KA2 3087
RPS6KA3 2973
PPP2R5D 2421
MAP3K7 2395
ATF2 2085
UBE2N 1936
MAP2K7 1654
AGER 1294
VRK3 1281
UBA52 1121
ELK1 1040
RIPK2 1025
NKIRAS1 375
NFKBIB -152
TRAF6 -229
PPP2R1B -241
HMGB1 -252
MEF2C -293
NFKB2 -1165
MAPK7 -1337
CREB1 -1378
RELA -1803
DUSP7 -3211
BTRC -4924
IKBKB -5386
S100B -5457
TRAF3 -5576
DUSP4 -6287
RPS27A -6938
MAPK9 -7068
IRF3 -8517
IRF7 -8657
MAPK8 -9428
IRAK2 -9548
RIPK1 -11074
BIRC3 -11125
CUL1 -11330
CASP8 -11336
RPS6KA5 -11594
SARM1 -12134
NOD1 -12263


ROS and RNS production in phagocytes

ROS and RNS production in phagocytes
925
set ROS and RNS production in phagocytes
setSize 31
pANOVA 8.23e-09
s.dist 0.598
p.adjustANOVA 1.75e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
ATP6V0A1 9423
ATP6V1A 9302
NCF4 9268
ATP6V0D1 9245
NCF2 9190
SLC11A1 9169
ATP6V0C 9127
ATP6V1B2 9057
ATP6V1D 9047
CYBB 9031
ATP6V0B 8598
ATP6V0E1 8596
ATP6V1C1 8539
ATP6V1H 8064
ATP6V1E1 8035
MPO 7437
NCF1 7334
TCIRG1 7188
CYBA 6922
LPO 6502

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ATP6V0A1 9423
ATP6V1A 9302
NCF4 9268
ATP6V0D1 9245
NCF2 9190
SLC11A1 9169
ATP6V0C 9127
ATP6V1B2 9057
ATP6V1D 9047
CYBB 9031
ATP6V0B 8598
ATP6V0E1 8596
ATP6V1C1 8539
ATP6V1H 8064
ATP6V1E1 8035
MPO 7437
NCF1 7334
TCIRG1 7188
CYBA 6922
LPO 6502
ATP6V1F 5878
ATP6V1E2 5730
RAC2 5163
HVCN1 4912
ATP6V1G1 3931
NOS1 1365
NOS3 -2059
ATP6V1C2 -2219
ATP6V1G2 -9515
ATP6V0E2 -11555
ATP6V0A2 -12211


Generic Transcription Pathway

Generic Transcription Pathway
446
set Generic Transcription Pathway
setSize 1085
pANOVA 1.09e-08
s.dist -0.103
p.adjustANOVA 2.28e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
FASLG -12371
TFDP2 -12364
RUNX3 -12352
ERBB2 -12320
NFATC2 -12294
ZNF599 -12232
PTPN4 -12220
RAD1 -12206
GATA3 -12191
ZNF287 -12168
ZNF3 -12165
RBBP7 -12155
YES1 -12142
PRKCQ -12127
AUTS2 -12089
ZNF530 -12068
MDC1 -12059
WRN -12047
TP53RK -12040
ZNF74 -12012

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FASLG -12371.0
TFDP2 -12364.0
RUNX3 -12352.0
ERBB2 -12320.0
NFATC2 -12294.0
ZNF599 -12232.0
PTPN4 -12220.0
RAD1 -12206.0
GATA3 -12191.0
ZNF287 -12168.0
ZNF3 -12165.0
RBBP7 -12155.0
YES1 -12142.0
PRKCQ -12127.0
AUTS2 -12089.0
ZNF530 -12068.0
MDC1 -12059.0
WRN -12047.0
TP53RK -12040.0
ZNF74 -12012.0
RPA1 -12004.0
MOV10 -11991.0
PRR5 -11985.0
RORA -11979.0
ANAPC1 -11962.0
ZNF461 -11956.0
FANCI -11927.0
ZNF33B -11911.0
ZNF549 -11908.0
ZNF250 -11889.0
DLL1 -11885.0
SMAD7 -11872.0
GLS -11862.0
NUAK1 -11853.0
AKT3 -11849.0
ZNF70 -11832.0
TNRC6C -11828.0
CAMK2D -11816.0
ZNF43 -11813.0
ZNF682 -11811.0
ZNF500 -11806.0
DYRK2 -11799.0
DGCR8 -11798.0
ZNF286A -11794.0
ZNF571 -11792.0
ZNF607 -11784.0
PARP1 -11764.0
SMAD3 -11745.0
CCND2 -11734.0
ZNF620 -11732.0
STAT1 -11727.0
RFC5 -11712.0
CCNE1 -11707.0
ZNF736 -11692.0
ZNF696 -11688.0
SMARCD1 -11679.0
ZNF568 -11661.0
ZNF554 -11652.0
PPP1R13B -11636.0
BRIP1 -11605.0
ZNF337 -11599.0
NR2C2AP -11589.0
ZNF724 -11586.0
ZNF517 -11582.0
ZNF570 -11569.0
FANCC -11548.0
COX11 -11539.0
DDB2 -11530.0
ZNF569 -11521.0
ZNF235 -11519.0
ATRIP -11486.0
MSH2 -11484.0
ZNF566 -11481.0
ZNF496 -11478.0
JMY -11472.0
ZNF707 -11464.0
ZNF30 -11462.0
KRBOX4 -11452.0
ZNF419 -11446.0
ZNF740 -11444.0
RAD9A -11435.0
ZNF136 -11433.0
FANCD2 -11424.0
RAD51D -11415.0
CENPJ -11406.0
ZNF773 -11396.0
PIP4K2C -11371.0
ZNF138 -11364.0
SUPT16H -11359.0
ZNF211 -11357.0
ZNF551 -11356.0
ZNF202 -11351.0
ZNF510 -11341.0
CUL1 -11330.0
PSMB9 -11324.0
ZNF600 -11320.0
CDC23 -11304.0
ZNF383 -11291.0
ZNF660 -11282.0
PPP2R5C -11265.0
CDK4 -11256.0
CNOT6L -11248.0
ZKSCAN8 -11246.0
ZNF528 -11244.0
ZNF248 -11241.0
ZNF649 -11216.0
ZNF354C -11213.0
ZNF14 -11212.0
ZNF343 -11182.0
ZFP30 -11171.0
RUNX2 -11163.0
SSRP1 -11162.0
ATM -11148.0
ZNF75D -11137.0
ZNF550 -11136.0
ZNF584 -11134.0
ZNF133 -11128.0
SKI -11113.0
ZNF519 -11101.0
ZNF540 -11097.0
WWOX -11085.0
ZNF77 -11084.0
PLXNA4 -11083.0
ZNF184 -11077.0
PCBP4 -11063.0
ZNF548 -11049.0
ITGA4 -11043.0
ZIK1 -11040.0
ZNF19 -11034.0
ZNF678 -11020.0
ZNF621 -11018.0
KIT -11004.0
BRD1 -10991.0
PMAIP1 -10986.0
ZNF324B -10972.0
ANAPC5 -10967.0
ZNF226 -10966.0
ZNF432 -10951.0
ZNF703 -10910.0
ZNF441 -10905.0
TP53 -10893.0
ZNF10 -10857.0
MECP2 -10855.0
ITGAL -10847.0
TP63 -10842.0
ZNF302 -10830.0
KAT2A -10771.0
L3MBTL2 -10770.0
KMT2A -10725.0
ZNF257 -10712.0
RFC4 -10702.0
ZNF23 -10692.0
ZNF180 -10670.0
ATAD2 -10660.0
ZNF253 -10652.0
PRMT6 -10628.0
NR3C2 -10625.0
FBXO32 -10607.0
ZNF585B -10598.0
ZNF266 -10587.0
DAXX -10575.0
ZNF563 -10567.0
ZFP1 -10563.0
ZNF790 -10520.0
MAF -10499.0
SIN3A -10493.0
ZNF420 -10490.0
RFC3 -10489.0
ZNF675 -10478.0
ZNF529 -10469.0
RPTOR -10464.0
ZNF544 -10460.0
ZNF749 -10456.0
ZNF473 -10444.0
SMYD2 -10431.0
ZNF595 -10393.0
CTLA4 -10363.0
ATR -10354.0
ZNF92 -10349.0
SMURF2 -10340.0
PSME2 -10336.0
ZNF112 -10327.0
NR1D2 -10325.0
RAD17 -10307.0
LDB1 -10303.0
ZNF778 -10297.0
ZNF680 -10286.0
AXIN1 -10285.0
IFNG -10277.0
ZNF446 -10274.0
GPAM -10241.0
ZNF799 -10216.0
ZFPM1 -10195.0
TCF7 -10173.0
ZFP14 -10160.0
ZNF212 -10128.0
WWP1 -10106.0
TGIF2 -10105.0
ZNF737 -10092.0
LRPPRC -10081.0
ING5 -10037.0
ZNF626 -10014.0
PSME1 -9991.0
ZNF224 -9977.0
PERP -9973.0
NFYB -9964.0
RBL1 -9959.0
CAMK4 -9956.0
NOP2 -9952.0
MGA -9948.0
ZNF436 -9945.0
EPC1 -9926.0
NR2C1 -9913.0
ZNF26 -9910.0
ZNF45 -9897.0
ZNF483 -9883.0
ZNF324 -9879.0
ZNF596 -9874.0
ZNF708 -9864.0
ZNF573 -9862.0
ZNF582 -9837.0
BMI1 -9829.0
ZNF664 -9828.0
SCO1 -9819.0
ZNF227 -9818.0
ZNF485 -9810.0
ZNF263 -9806.0
GATA2 -9800.0
MED15 -9778.0
MTOR -9767.0
HEY2 -9752.0
EZH2 -9741.0
CHD3 -9737.0
ZNF157 -9718.0
ZNF583 -9711.0
ZNF311 -9705.0
BRD2 -9688.0
RICTOR -9670.0
ZNF704 -9660.0
ZNF793 -9654.0
ZNF597 -9642.0
ZNF431 -9641.0
ZNF470 -9630.0
ZFP90 -9613.0
TXNIP -9600.0
ZNF354B -9598.0
ZNF684 -9580.0
ZNF614 -9572.0
ZNF689 -9559.0
NPM1 -9532.0
ZNF484 -9525.0
ZSCAN25 -9513.0
ZFP69 -9488.0
CCNT1 -9469.0
FOXO1 -9465.0
IGFBP3 -9455.0
ZNF506 -9443.0
ZNF41 -9405.0
ZNF17 -9349.0
EED -9348.0
TRPC3 -9343.0
ZNF767P -9339.0
ZNF625 -9336.0
ZNF606 -9322.0
CBX5 -9272.0
ESR2 -9250.0
PRMT1 -9229.0
MED27 -9191.0
TBP -9167.0
ZNF141 -9154.0
ZNF677 -9144.0
PSMC4 -9127.0
ESR1 -9122.0
ZNF727 -9121.0
ZNF782 -9113.0
ZNF738 -9086.0
ZNF709 -9071.0
ZNF699 -9037.0
ZNF317 -9010.0
ZNF439 -9000.0
ZNF160 -8989.0
ZNF567 -8988.0
NR1D1 -8980.0
SESN1 -8962.0
ZNF721 -8922.0
RPA3 -8911.0
ZNF416 -8903.0
ZNF681 -8899.0
SMARCC1 -8880.0
SIRT3 -8857.0
PRDM1 -8856.0
ZNF792 -8839.0
TRIM33 -8823.0
SRC -8820.0
ZNF433 -8780.0
ZNF79 -8769.0
ZNF140 -8760.0
ZNF619 -8735.0
ZNF440 -8730.0
AIFM2 -8727.0
ZNF717 -8709.0
ZNF331 -8698.0
PML -8693.0
EHMT1 -8692.0
MNAT1 -8687.0
TGIF1 -8682.0
ZNF274 -8667.0
NR2C2 -8630.0
MED10 -8579.0
RORC -8573.0
E2F5 -8568.0
EHMT2 -8558.0
MEN1 -8538.0
ZFP37 -8513.0
FOXP3 -8503.0
ZNF234 -8487.0
ZNF300 -8481.0
TAF1 -8476.0
ZNF559 -8467.0
L3MBTL1 -8461.0
PHC1 -8402.0
CDK13 -8392.0
MAPKAPK5 -8364.0
SMAD4 -8351.0
HDAC6 -8337.0
SKP2 -8279.0
HES1 -8266.0
CDKN1B -8207.0
PRKAB2 -8172.0
PHC3 -8152.0
ZKSCAN3 -8126.0
MEAF6 -8105.0
LEF1 -8076.0
TAF4B -8069.0
ZNF720 -8041.0
ZNF665 -7990.0
ZNF175 -7950.0
MRE11 -7923.0
GLI3 -7910.0
ZNF726 -7889.0
ZNF641 -7885.0
ZNF688 -7872.0
BBC3 -7864.0
CDC7 -7855.0
ZNF135 -7853.0
ZNF521 -7834.0
ZNF12 -7825.0
RGCC -7821.0
ZNF585A -7814.0
ZNF671 -7797.0
PIP4K2B -7788.0
ERCC3 -7783.0
ZNF75A -7752.0
RBL2 -7743.0
ZNF382 -7731.0
TNFRSF18 -7726.0
GLS2 -7702.0
ZNF702P -7701.0
ZNF771 -7686.0
ZNF2 -7673.0
ZNF320 -7647.0
ZNF273 -7623.0
PSMA8 -7606.0
ZNF577 -7605.0
ZNF418 -7559.0
ZNF791 -7534.0
RBM14 -7497.0
ACTL6A -7468.0
ZNF264 -7412.0
ANAPC2 -7407.0
MED24 -7387.0
YAF2 -7378.0
RAD50 -7373.0
TAF6 -7352.0
YWHAQ -7340.0
MTA2 -7317.0
ZNF711 -7253.0
ZNF195 -7249.0
BRPF1 -7218.0
TCF3 -7215.0
IL2RA -7161.0
GAMT -7054.0
ZNF785 -7032.0
ZNF777 -6997.0
CCND1 -6970.0
RPS27A -6938.0
ZNF764 -6912.0
ZNF786 -6907.0
ZNF223 -6903.0
ZNF425 -6900.0
ZNF268 -6887.0
COX19 -6882.0
MLH1 -6872.0
ZFP28 -6824.0
MED23 -6787.0
NR4A1 -6756.0
SUPT5H -6716.0
PIDD1 -6647.0
ANAPC4 -6644.0
ZNF33A -6630.0
ZNF691 -6627.0
BRPF3 -6615.0
ZKSCAN7 -6609.0
FBXW7 -6600.0
GAD2 -6585.0
ZNF415 -6564.0
H2BU1 -6555.0
CDK6 -6465.0
ZNF480 -6459.0
TAF15 -6454.0
RHNO1 -6437.0
PPARD -6394.0
THRA -6387.0
ZNF616 -6382.0
TJP1 -6374.0
FOXO6 -6367.0
ZNF208 -6363.0
RPA2 -6306.0
NELFCD -6277.0
TFAP2E -6266.0
AGRP -6243.0
ZNF169 -6234.0
ZNF442 -6204.0
TCF7L2 -6185.0
ZNF610 -6184.0
RNF34 -6150.0
WWTR1 -6131.0
COX18 -6126.0
KRBA1 -6098.0
PSME4 -6087.0
KMT2E -6073.0
CDC16 -6071.0
PSMA5 -6053.0
ZNF706 -6049.0
ZNF493 -6035.0
ZNF557 -5971.0
PCNA -5969.0
ZNF662 -5963.0
ZNF154 -5946.0
TAF2 -5945.0
ZNF543 -5942.0
ZNF398 -5842.0
SCMH1 -5839.0
NOC2L -5831.0
ZNF761 -5813.0
E2F7 -5780.0
SETD1A -5744.0
PSMB10 -5735.0
ZNF713 -5668.0
ZNF514 -5664.0
ZNF718 -5657.0
ZNF101 -5614.0
TNRC6A -5613.0
MAMLD1 -5584.0
ZNF658 -5581.0
ZNF34 -5577.0
ZFP69B -5558.0
ZNF71 -5533.0
ZNF589 -5519.0
PMS2 -5514.0
ARID1B -5504.0
TNKS1BP1 -5490.0
MED30 -5484.0
ZNF25 -5459.0
ZNF417 -5416.0
BLK -5388.0
ZNF99 -5349.0
ZNF615 -5323.0
ZNF547 -5291.0
PSMA3 -5285.0
RABGGTB -5240.0
ZNF285 -5239.0
CDKN2A -5236.0
ZNF37A -5230.0
NOTCH4 -5229.0
CCNT2 -5205.0
BTG1 -5201.0
ANAPC7 -5181.0
ZKSCAN4 -5161.0
RARG -5153.0
ZNF443 -5146.0
RBBP8 -5105.0
NR4A3 -5082.0
TRIM28 -5056.0
PPARGC1B -5047.0
COX20 -5018.0
ZNF155 -5014.0
CDK2 -5006.0
ANAPC10 -5000.0
E2F6 -4979.0
SOCS4 -4974.0
ZNF124 -4952.0
ZNF430 -4837.0
ZNF546 -4802.0
TP73 -4754.0
ZNF692 -4722.0
ZNF700 -4710.0
BLM -4690.0
ZNF611 -4678.0
ZNF492 -4623.0
CBX2 -4617.0
ZNF564 -4519.0
TNRC6B -4518.0
CHD4 -4515.0
TAF5 -4514.0
ZNF460 -4477.0
NR1I2 -4435.0
ZNF197 -4430.0
ZNF426 -4382.0
SCO2 -4351.0
CHEK2 -4350.0
SMARCE1 -4315.0
ZNF561 -4292.0
CNOT1 -4265.0
SIN3B -4205.0
SIRT1 -4197.0
SMARCC2 -4137.0
PCGF2 -4135.0
RING1 -4063.0
RMI2 -4050.0
ZNF486 -4043.0
MED1 -4036.0
POLR2D -4024.0
ARID2 -3932.0
ZNF233 -3931.0
CDK9 -3927.0
YEATS4 -3919.0
NELFA -3886.0
CNOT7 -3880.0
SMARCB1 -3869.0
PRELID3A -3832.0
TEAD2 -3774.0
ZNF334 -3744.0
ZSCAN32 -3733.0
ZNF215 -3708.0
PAX5 -3638.0
NR1H3 -3597.0
ZNF676 -3587.0
ZNF701 -3558.0
SESN3 -3546.0
GPX2 -3533.0
ZNF350 -3507.0
ZNF655 -3460.0
ZNF556 -3455.0
TOPBP1 -3450.0
CASP10 -3446.0
BARD1 -3419.0
BCL2L14 -3367.0
PCGF5 -3312.0
ZNF714 -3298.0
ZNF624 -3294.0
RXRB -3276.0
UXT -3252.0
PIN1 -3188.0
ZFP2 -3134.0
ZNF221 -3101.0
POLR2A -3092.0
PSMB8 -3076.0
ZNF670 -3075.0
CTSV -3036.0
POLR2H -2942.0
TAF11 -2938.0
GTF2H4 -2916.0
GTF2H1 -2913.0
DNA2 -2858.0
CASP6 -2831.0
HIVEP3 -2798.0
RAD51 -2767.0
PLK2 -2748.0
ZNF555 -2741.0
SMARCA2 -2737.0
CNOT10 -2718.0
TTC5 -2650.0
ZNF490 -2630.0
ABCA6 -2612.0
TAF9B -2599.0
SMURF1 -2591.0
ZNF605 -2576.0
ZNF18 -2548.0
POLR2B -2523.0
ZNF772 -2509.0
CHEK1 -2481.0
CASP2 -2471.0
RABGGTA -2462.0
KAT2B -2414.0
SUZ12 -2409.0
DDIT4 -2395.0
PIP4K2A -2365.0
H19 -2361.0
ZNF860 -2350.0
OCLN -2327.0
GTF2H3 -2235.0
FZR1 -2233.0
ZNF839 -2202.0
ANAPC16 -2123.0
TSC1 -2118.0
CNOT2 -2090.0
CALM1 -2081.0
CDK8 -1971.0
PHF20 -1921.0
KCTD1 -1890.0
RBBP4 -1870.0
HSPD1 -1860.0
TAF3 -1850.0
RELA -1803.0
POLR2K -1783.0
GATAD2B -1759.0
NR2F1 -1717.0
ZNF468 -1709.0
TAF4 -1698.0
RFFL -1683.0
ZNF669 -1660.0
ZNF28 -1618.0
NR4A2 -1601.0
EXO1 -1586.0
COX14 -1496.0
BGLAP -1473.0
CREB1 -1378.0
CDK12 -1356.0
ZNF750 -1354.0
CYCS -1334.0
CNOT4 -1286.0
SETD9 -1240.0
TCF12 -1233.0
MDM4 -1230.0
H2AZ2 -1209.0
CDK5R1 -1089.0
STUB1 -1032.0
ZNF627 -1022.0
AGO3 -1011.0
ZNF562 -962.0
TCEA1 -943.0
ZNF565 -941.0
GPS2 -889.0
PSMC5 -863.0
MED6 -842.0
TSC2 -804.0
UBE2I -764.0
SKIL -725.0
MOBP -714.0
RRAGB -713.0
PCGF6 -689.0
ZNF558 -678.0
CDC27 -651.0
PSMA4 -616.0
NPPA -584.0
MAML2 -582.0
MBD3 -528.0
ZNF716 -489.0
MEF2C -293.0
PPP2R1B -241.0
MED14 -203.0
RRM2 -183.0
ZNF587 -164.0
ZNF200 -154.0
HUS1 -145.0
ZNF222 -84.0
ZNF347 -31.0
BRD7 -10.0
MT-CO3 40.0
MT-CO2 48.0
KMT2C 63.0
COX16 132.0
WDR5 155.0
KLF4 157.0
APOE 218.0
MED7 224.0
ABL1 226.0
TCF7L1 275.0
ZNF100 276.0
TRIAP1 281.0
MYB 302.0
ZNF776 367.0
NELFB 374.0
MLST8 376.0
CSF1R 394.0
POLR2I 396.0
PPP1R13L 399.0
AKT2 433.0
PLAGL1 446.0
CCNB1 467.0
NR3C1 511.0
YY1 537.0
COX7C 564.0
CCNA1 585.0
HDAC1 587.0
CLDN5 650.0
MT-CO1 684.0
BANP 687.0
COX6C 706.0
SETD1B 736.0
CCNH 774.0
KAT6A 794.0
PPARA 813.0
AURKB 846.0
RBBP5 1037.0
ZNF429 1053.0
UBA52 1121.0
KMT2B 1179.0
GCK 1193.0
TAF9 1250.0
PRKAB1 1302.0
KAT5 1314.0
ITCH 1318.0
ZNF394 1319.0
PRKAA1 1322.0
ZKSCAN5 1336.0
HDAC9 1359.0
THRB 1429.0
MED31 1462.0
CDK1 1540.0
TPX2 1551.0
PSMD10 1559.0
ATXN3 1601.0
SFN 1615.0
POLR2C 1616.0
ELF1 1630.0
CCNA2 1685.0
KCTD15 1758.0
TNFRSF10A 1815.0
PVALB 1839.0
NR1I3 1855.0
CCNC 1877.0
CAMK2G 1921.0
ZNF658B 1948.0
ZNF613 1957.0
CAV1 1969.0
PSMC3 1976.0
PRKAG2 2015.0
MED12 2034.0
CBFB 2078.0
ATF2 2085.0
CNOT11 2102.0
TAF7 2139.0
OPRM1 2161.0
ZKSCAN1 2166.0
CBX4 2222.0
NBN 2267.0
CHM 2273.0
HDAC10 2280.0
STK11 2289.0
MYC 2304.0
PSMB4 2523.0
MED13 2533.0
PSMC2 2598.0
MYBL2 2601.0
ELF2 2606.0
PSMD14 2611.0
DEK 2676.0
NRBP1 2786.0
SLC38A9 2807.0
POMC 2855.0
E2F8 2856.0
ZNF471 2869.0
CCNK 2877.0
ZNF586 2878.0
SUPT4H1 2890.0
CDC26 2923.0
ZNF770 2964.0
GTF2H2 2984.0
AGO2 2995.0
VENTX 3057.0
GATAD2A 3075.0
HDAC8 3079.0
MED17 3084.0
RAD9B 3090.0
BTG2 3111.0
KMT2D 3203.0
HTT 3209.0
MED4 3215.0
SESN2 3311.0
AURKA 3330.0
ZNF445 3333.0
PSMB1 3374.0
CREBBP 3423.0
PSMD5 3426.0
PRDX2 3428.0
ZNF189 3487.0
NFYA 3506.0
POLR2G 3508.0
RNF2 3513.0
ZNF205 3530.0
SURF1 3532.0
ERCC2 3547.0
PRMT5 3600.0
AKT1 3614.0
KRAS 3702.0
FAS 3712.0
JUN 3722.0
ZNF668 3725.0
BIRC5 3738.0
ZNF667 3739.0
DPY30 3757.0
MAPK11 3826.0
TMEM219 3845.0
NELFE 3860.0
GTF2H5 3874.0
ZNF354A 3889.0
RBX1 3934.0
ZNF747 3949.0
CSNK2B 3969.0
PPARGC1A 3988.0
ZNF333 4007.0
CBX6 4033.0
PSMB2 4084.0
COX4I1 4191.0
CASP1 4224.0
CTSL 4231.0
MAX 4243.0
SKP1 4287.0
MDM2 4312.0
SEM1 4348.0
KCTD6 4371.0
SOD2 4390.0
MED26 4395.0
TACO1 4406.0
ING2 4415.0
UBC 4439.0
LAMTOR4 4441.0
COX7B 4465.0
CDKN1A 4511.0
TBL1XR1 4556.0
PPP2R1A 4589.0
SGK1 4595.0
POLR2F 4604.0
PSMD3 4618.0
NDRG1 4647.0
HDAC3 4673.0
ZNF552 4685.0
ZNF20 4697.0
NOTCH1 4704.0
HDAC5 4710.0
SMARCA4 4733.0
UBE2S 4746.0
ZNF774 4747.0
HDAC11 4756.0
CNOT6 4799.0
DLX6 4817.0
CBX3 4825.0
ARID1A 4830.0
AR 4840.0
CCNG1 4881.0
ZNF282 4892.0
SMAD2 4905.0
DDIT3 4906.0
RFC2 4948.0
GTF2F1 4951.0
RRAGC 4954.0
CDC25C 4969.0
H2AC20 4972.0
NR2F6 4984.0
ELL 5009.0
ZNF775 5041.0
MAPKAP1 5057.0
CTSK 5059.0
COX6A1 5095.0
UBE2C 5101.0
GPRIN1 5131.0
CCNE2 5143.0
TGFB1 5153.0
SNW1 5201.0
CDK7 5211.0
CRADD 5216.0
NOTCH2 5272.0
MED16 5278.0
POLR2L 5305.0
H2BC15 5312.0
PTPN11 5314.0
CNOT3 5320.0
PSMA2 5339.0
H2BC9 5394.0
MAML1 5404.0
GTF2F2 5434.0
CBX8 5448.0
FOS 5460.0
USP9X 5464.0
PRKAG1 5476.0
HDAC2 5482.0
TP53BP2 5532.0
RYBP 5535.0
PBRM1 5566.0
G6PC 5568.0
YWHAZ 5624.0
AGO1 5654.0
COX6B1 5667.0
PF4 5707.0
PTPN1 5722.0
KDM5B 5736.0
RNF111 5749.0
PSMD8 5757.0
PRELID1 5790.0
HIPK1 5855.0
NCOR1 5887.0
BAX 5916.0
ESRRA 5943.0
PSMD13 5948.0
ZNF213 5950.0
THBS1 5951.0
PSMD7 5963.0
PSMA6 5970.0
STEAP3 5996.0
ASH2L 6001.0
ZNF385A 6014.0
BID 6020.0
H2AZ1 6036.0
HIPK2 6078.0
HDAC7 6122.0
EP300 6129.0
IRAK1 6131.0
PDPK1 6136.0
ANAPC11 6161.0
COX5A 6168.0
CTDP1 6180.0
CSNK2A1 6199.0
TIGAR 6204.0
COX5B 6207.0
MED25 6209.0
PSMD11 6231.0
RRAGA 6244.0
BRCA1 6248.0
NFKB1 6277.0
GP1BA 6279.0
GPI 6284.0
E2F4 6300.0
USP7 6323.0
E2F1 6343.0
YWHAB 6385.0
CSNK2A2 6388.0
FOXO4 6391.0
CTNNB1 6408.0
RARA 6429.0
CITED2 6457.0
TP53INP1 6458.0
NDUFA4 6459.0
TAL1 6518.0
SREBF1 6539.0
PSMD12 6556.0
COX8A 6611.0
CCNG2 6629.0
GSK3B 6634.0
PSMC6 6635.0
UBB 6639.0
PSMF1 6659.0
POLR2J 6671.0
PLK3 6680.0
ZNF230 6689.0
H3C15 6699.5
TWIST2 6721.0
MED20 6743.0
UBE2E1 6759.0
SATB2 6781.0
RRM2B 6798.0
JUNB 6806.0
PSMB6 6813.0
SUMO1 6889.0
ZNF710 6900.0
SMARCD2 6914.0
RMI1 6947.0
PSMC1 7021.0
PRDX1 7030.0
PSMA7 7096.0
PRKCB 7097.0
TAF10 7110.0
PSMB3 7171.0
ZNF267 7203.0
TAF13 7217.0
PSMD1 7241.0
H2BC17 7285.0
ELOA 7312.0
PSMA1 7329.0
BCL2L11 7384.0
H2BC4 7389.0
PSMD2 7411.0
NR1H2 7415.0
ZFHX3 7425.0
VEGFA 7467.0
ELOB 7482.0
SERPINE1 7483.0
CCND3 7487.0
MAPK1 7493.0
RXRA 7495.0
ELOC 7519.0
RUNX1 7529.0
MED8 7535.0
POLR2E 7563.0
LAMTOR2 7567.0
ZNF746 7573.0
LAMTOR3 7574.0
PSMD9 7620.0
NFYC 7653.0
ITGA5 7659.0
RHEB 7669.0
MYL9 7703.0
PPP2CB 7712.0
COX7A2L 7719.0
PPM1D 7810.0
SMAD6 7835.0
CITED4 7844.0
PSMD6 7846.0
NEDD4L 7875.0
TBL1X 7887.0
NOTCH3 7899.0
H2BC11 7912.0
H2AC6 7934.0
TNFRSF10C 7960.0
TOP3A 7973.0
TAF12 7977.0
NCOR2 7985.0
CEBPB 7997.0
H2BC5 8003.0
KMT5A 8005.0
NRBF2 8076.0
PSMB5 8101.0
LBR 8102.0
TXNRD1 8192.0
SP1 8193.0
PPM1A 8200.0
CNOT8 8227.0
PPP2CA 8234.0
PSME3 8251.0
TXN 8285.0
LMO2 8307.0
TNFRSF10B 8321.0
VDR 8348.0
PSMD4 8402.0
GATA1 8410.0
PTEN 8460.0
TFDP1 8470.0
PSMB7 8485.0
LAMTOR5 8498.0
SMAD1 8511.0
PRDX5 8531.0
NR6A1 8553.0
ARID3A 8584.0
CDK5 8616.0
UBE2D3 8640.0
YWHAH 8649.0
H3-3A 8661.0
SMARCD3 8668.0
FOXO3 8682.0
RB1 8707.0
JAG1 8743.0
LGALS3 8752.0
RRAGD 8753.0
RBPJ 8770.0
CDKN2B 8836.0
MAP2K6 8887.0
TGFA 8889.0
SPI1 8891.0
ITGA2B 8893.0
PINK1 8941.0
MAPK3 8953.0
MAML3 8957.0
HDAC4 8960.0
ANAPC15 8968.0
TP53I3 8979.0
RETN 8998.0
ZNF697 9002.0
G6PD 9004.0
APAF1 9015.0
CARM1 9020.0
SLC2A3 9021.0
PHC2 9043.0
YWHAE 9045.0
H2BC12 9051.0
AGO4 9070.0
TNFRSF10D 9072.0
GADD45A 9083.0
FKBP5 9091.0
MAPK14 9104.0
CAT 9123.0
BCL6 9175.0
UBE2D1 9187.0
GSR 9235.0
YWHAG 9264.0
H2BC21 9283.0
BNIP3L 9329.0
H2AJ 9374.0
NLRC4 9406.0
LAMTOR1 9411.0
PRKACA 9429.0
NFE2 9431.0
SOCS3 9476.0
CR1 9486.0
PPARG 9522.0


Cellular responses to external stimuli

Cellular responses to external stimuli
169
set Cellular responses to external stimuli
setSize 506
pANOVA 1.91e-08
s.dist 0.146
p.adjustANOVA 3.95e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
H1-2 9491
GRB10 9439
LAMTOR1 9411
H2AJ 9374
PRDX3 9366
LMNB1 9345
GPX1 9314
ATP6V1A 9302
H2BC21 9283
NCF4 9268
ATP6V0D1 9245
GSR 9235
NCF2 9190
UBE2D1 9187
DCTN2 9157
ATP6V0C 9127
CAT 9123
MAPK14 9104
FKBP5 9091
AGO4 9070

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H1-2 9491.0
GRB10 9439.0
LAMTOR1 9411.0
H2AJ 9374.0
PRDX3 9366.0
LMNB1 9345.0
GPX1 9314.0
ATP6V1A 9302.0
H2BC21 9283.0
NCF4 9268.0
ATP6V0D1 9245.0
GSR 9235.0
NCF2 9190.0
UBE2D1 9187.0
DCTN2 9157.0
ATP6V0C 9127.0
CAT 9123.0
MAPK14 9104.0
FKBP5 9091.0
AGO4 9070.0
ATP6V1B2 9057.0
H2BC12 9051.0
ATP6V1D 9047.0
YWHAE 9045.0
PHC2 9043.0
CYBB 9031.0
ANAPC15 8968.0
MAPK3 8953.0
ERO1A 8943.0
PRDX6 8937.0
MTF1 8925.0
MAP2K6 8887.0
CDKN2B 8836.0
NUP58 8820.0
RRAGD 8753.0
MAP2K3 8748.0
RB1 8707.0
H3-3A 8661.0
UBE2D3 8640.0
E2F2 8601.0
ATP6V0B 8598.0
CAPZA2 8597.0
ATP6V0E1 8596.0
KDM6B 8577.0
ATP6V1C1 8539.0
PRDX5 8531.0
LAMTOR5 8498.0
PSMB7 8485.0
EIF2AK1 8482.0
TFDP1 8470.0
P4HB 8440.0
MAP4K4 8425.0
PSMD4 8402.0
DCTN4 8387.0
MAPKAPK3 8382.0
BAG4 8328.0
TXN 8285.0
PSME3 8251.0
SP1 8193.0
TXNRD1 8192.0
HSBP1 8173.0
CAPZA1 8135.0
PSMB5 8101.0
STAT3 8098.0
ETS2 8092.0
HSPA1A 8071.0
DNAJB6 8066.0
ATP6V1H 8064.0
ARNT 8047.0
ATP6V1E1 8035.0
CAPZB 8015.0
H2BC5 8003.0
CEBPB 7997.0
H2AC6 7934.0
NUP214 7921.0
H2BC11 7912.0
EPAS1 7886.0
AKT1S1 7865.0
CDKN2D 7853.0
PSMD6 7846.0
CSRP1 7829.0
DYNC1I2 7735.0
DNAJC7 7701.0
RPS6KA1 7695.0
MAP3K5 7682.0
RHEB 7669.0
MT1F 7632.0
PSMD9 7620.0
ACTR10 7605.0
LAMTOR3 7574.0
LAMTOR2 7567.0
TXNRD2 7526.0
ELOC 7519.0
MAPK1 7493.0
H1-0 7492.0
ELOB 7482.0
VEGFA 7467.0
HIF1A 7436.0
PSMD2 7411.0
HIGD1A 7394.0
H2BC4 7389.0
BMT2 7350.0
NCF1 7334.0
PSMA1 7329.0
DCTN6 7300.0
H2BC17 7285.0
PSMD1 7241.0
TCIRG1 7188.0
RPL26L1 7176.0
PSMB3 7171.0
PSMA7 7096.0
HSPA2 7081.0
PRDX1 7030.0
HSPA5 7029.0
PSMC1 7021.0
ACTR1A 7002.0
DYNC1LI1 6941.0
CYBA 6922.0
VCP 6886.0
MAP2K4 6866.0
PSMB6 6813.0
CDKN2C 6811.0
UBE2E1 6759.0
EIF2S3 6747.0
H3C15 6699.5
PSMF1 6659.0
E2F3 6650.0
UBB 6639.0
PSMC6 6635.0
GSK3B 6634.0
EGLN1 6604.0
PSMD12 6556.0
IGFBP7 6545.0
HSPA6 6514.0
HSPA1B 6470.0
CITED2 6457.0
BAG1 6396.0
E2F1 6343.0
NFKB1 6277.0
KPTN 6265.0
RRAGA 6244.0
ATF4 6237.0
PSMD11 6231.0
EIF2S2 6175.0
ANAPC11 6161.0
EP300 6129.0
HSF1 6063.0
H2AZ1 6036.0
DCTN3 5994.0
PPP1R15A 5981.0
PSMA6 5970.0
PSMD7 5963.0
DYNLL1 5952.0
PSMD13 5948.0
ATP6V1F 5878.0
PSMD8 5757.0
SEC13 5748.0
ATP6V1E2 5730.0
AGO1 5654.0
FNIP1 5603.0
DNAJA2 5589.0
CEBPG 5466.0
FOS 5460.0
MT1X 5452.0
CBX8 5448.0
DNAJA1 5425.0
RPS9 5421.0
H2BC9 5394.0
UBN1 5358.0
HSPA4 5350.0
PSMA2 5339.0
H2BC15 5312.0
RAE1 5164.0
CCNE2 5143.0
UBE2C 5101.0
DCTN1 5078.0
TERF2IP 5040.0
H2AC20 4972.0
RRAGC 4954.0
ID1 4927.0
DDIT3 4906.0
AR 4840.0
UBE2S 4746.0
UBE2D2 4657.0
TXN2 4651.0
PSMD3 4618.0
TINF2 4592.0
NUP50 4521.0
CDKN1A 4511.0
NPRL3 4510.0
RPL3L 4503.0
LAMTOR4 4441.0
UBC 4439.0
ERF 4400.0
SOD2 4390.0
SEM1 4348.0
ATOX1 4338.0
MAPK10 4325.0
MDM2 4312.0
EIF2S1 4279.0
DYNC1LI2 4273.0
DYNC1I1 4187.0
PTGES3 4125.0
PSMB2 4084.0
MAPKAPK2 4054.0
CBX6 4033.0
RBX1 3934.0
ATP6V1G1 3931.0
MAPK11 3826.0
JUN 3722.0
MINK1 3687.0
VHL 3674.0
FLCN 3622.0
EGLN2 3578.0
RNF2 3513.0
PRDX2 3428.0
PSMD5 3426.0
CREBBP 3423.0
MIOS 3378.0
PSMB1 3374.0
DEDD2 3327.0
SESN2 3311.0
HSPA1L 3102.0
NUP98 3101.0
RPS6KA2 3087.0
NUP37 3074.0
VENTX 3057.0
NUDT2 2988.0
RPS6KA3 2973.0
CDC26 2923.0
SLC38A9 2807.0
RPS19BP1 2709.0
PSMD14 2611.0
PSMC2 2598.0
CUL2 2526.0
PSMB4 2523.0
NBN 2267.0
HSPA12B 2254.0
CBX4 2222.0
H1-4 2207.0
MRPL18 2144.0
ATF2 2085.0
RPS27L 2061.0
PSMC3 1976.0
CAMK2G 1921.0
CXCL8 1729.0
CCNA2 1685.0
MAP2K7 1654.0
PSMD10 1559.0
CCS 1538.0
HSP90AA1 1326.0
KAT5 1314.0
NOX5 1175.0
WDR24 1150.0
UBA52 1121.0
NOX4 1114.0
FKBP4 832.0
NUP62 769.0
ATP7A 694.0
GPX3 680.0
CCNA1 585.0
NR3C1 511.0
RPS4Y1 424.0
MLST8 376.0
GSTP1 135.0
HMGA1 117.0
DEPDC5 102.0
EIF2AK4 41.0
RPL36AL 32.0
RPLP1 19.0
HIKESHI -103.0
RPS24 -263.0
FAU -362.0
MT1E -432.0
EGLN3 -437.0
PSMA4 -616.0
CDC27 -651.0
RRAGB -713.0
RANBP2 -820.0
PSMC5 -863.0
DNAJA4 -881.0
RPL15 -963.0
RPLP0 -1000.0
AGO3 -1011.0
HSPA13 -1157.0
RPL8 -1187.0
H2AZ2 -1209.0
MDM4 -1230.0
ST13 -1254.0
CYCS -1334.0
MAPK7 -1337.0
RPS26 -1430.0
RPL28 -1462.0
RPL22L1 -1619.0
RPS13 -1749.0
HSPA12A -1760.0
RELA -1803.0
RBBP4 -1870.0
RPL9 -1872.0
RPL7 -1955.0
RPS8 -2083.0
STIP1 -2094.0
ANAPC16 -2123.0
ATP6V1C2 -2219.0
FZR1 -2233.0
SUZ12 -2409.0
HIF3A -2519.0
RPL27 -2855.0
FNIP2 -2881.0
HSPA4L -2948.0
RPL39 -3006.0
NUP85 -3049.0
PSMB8 -3076.0
BAG3 -3170.0
IMPACT -3210.0
RPL23 -3314.0
RPL6 -3354.0
RPL13 -3431.0
GPX2 -3533.0
RPL4 -3582.0
TERF1 -3601.0
RPL29 -3611.0
RPL7A -3665.0
RPS15 -3673.0
RPL37A -3946.0
DYNLL2 -3980.0
RING1 -4063.0
RPS21 -4079.0
DCTN5 -4086.0
SIRT1 -4197.0
POT1 -4355.0
TERF2 -4464.0
RPS2 -4499.0
HIF1AN -4510.0
TNRC6B -4518.0
RPL31 -4541.0
CBX2 -4617.0
RPS16 -4669.0
RPS3A -4694.0
RPS28 -4713.0
RPL5 -4728.0
RPL22 -4740.0
SOD1 -4862.0
BAG5 -4887.0
DNAJC2 -4961.0
RPS7 -4968.0
ANAPC10 -5000.0
CDK2 -5006.0
RPL18 -5080.0
EEF1A1 -5087.0
ANAPC7 -5181.0
CDKN2A -5236.0
PSMA3 -5285.0
RPL36 -5287.0
ATF5 -5305.0
SZT2 -5322.0
RPL17 -5431.0
RPS14 -5463.0
NUP42 -5564.0
TNRC6A -5613.0
DNAJB1 -5672.0
RPS5 -5691.0
PSMB10 -5735.0
RPS15A -5742.0
RPS10 -5793.0
RPL24 -5799.0
SCMH1 -5839.0
RPL38 -5840.0
TRIB3 -5843.0
RPS3 -5914.0
RPS12 -5987.0
RPL35A -6015.0
PSMA5 -6053.0
SEH1L -6069.0
RPL18A -6070.0
CDC16 -6071.0
PSME4 -6087.0
RPS6 -6160.0
RPS17 -6247.0
RPL27A -6257.0
RPL11 -6261.0
RPL19 -6281.0
RPS4X -6285.0
RPS23 -6292.0
RPA2 -6306.0
NUP153 -6321.0
RPSA -6323.0
RPS25 -6365.0
RPL37 -6375.0
RPL21 -6458.0
CDK6 -6465.0
RLN1 -6482.0
RPL10 -6534.0
EP400 -6550.0
H2BU1 -6555.0
RPL26 -6612.0
ANAPC4 -6644.0
RPL10A -6686.0
RPL32 -6709.0
RPL14 -6710.0
RPL34 -6802.0
HSP90AB1 -6863.0
RPL41 -6866.0
RPS27A -6938.0
RPS19 -6965.0
MT2A -6990.0
RPL30 -7020.0
TPR -7028.0
RPL12 -7053.0
MAPK9 -7068.0
RPLP2 -7087.0
POM121C -7188.0
WTIP -7208.0
RPS11 -7243.0
RAD50 -7373.0
RPL36A -7376.0
ANAPC2 -7407.0
PSMA8 -7606.0
DYNC1H1 -7685.0
RPS18 -7744.0
NUP133 -7762.0
ACD -7800.0
MRE11 -7923.0
AJUBA -7927.0
RPS29 -7940.0
BAG2 -7997.0
RPL35 -8092.0
PHC3 -8152.0
CDKN1B -8207.0
RPL13A -8212.0
HSPA7 -8236.0
POM121 -8299.0
ASNS -8316.0
HDAC6 -8337.0
MAPKAPK5 -8364.0
AAAS -8389.0
PHC1 -8402.0
NUP54 -8479.0
EHMT2 -8558.0
RPL3 -8561.0
EHMT1 -8692.0
RPL39L -8805.0
SH3BP4 -8881.0
RPS20 -8886.0
GPX7 -8901.0
RPA3 -8911.0
SESN1 -8962.0
PSMC4 -9127.0
WDR59 -9240.0
EED -9348.0
HSPA14 -9380.0
HSPH1 -9407.0
MAPK8 -9428.0
ATP6V1G2 -9515.0
NUP43 -9517.0
RPL23A -9567.0
HIRA -9628.0
ATF3 -9677.0
EZH2 -9741.0
RPS27 -9756.0
MTOR -9767.0
HSPA9 -9780.0
ASF1A -9781.0
BMI1 -9829.0
PSME1 -9991.0
SERPINH1 -10121.0
CCAR2 -10156.0
NUP155 -10233.0
PSME2 -10336.0
ATR -10354.0
GCN1 -10372.0
NUP107 -10421.0
RPTOR -10464.0
NUP160 -10557.0
CABIN1 -10590.0
NUP35 -10611.0
NR3C2 -10625.0
ITFG2 -10719.0
NUP210 -10726.0
LIMD1 -10791.0
TP53 -10893.0
HSPA8 -10922.0
C12orf66 -10960.0
ANAPC5 -10967.0
ATM -11148.0
CDK4 -11256.0
CDC23 -11304.0
NUP205 -11321.0
PSMB9 -11324.0
ETS1 -11386.0
NUP88 -11397.0
ATP6V0E2 -11555.0
NPRL2 -11604.0
NUP93 -11620.0
NUP188 -11624.0
TNIK -11674.0
CCNE1 -11707.0
CAMK2D -11816.0
TNRC6C -11828.0
ANAPC1 -11962.0
MOV10 -11991.0
RPA1 -12004.0
RBBP7 -12155.0
NDC1 -12173.0
TNFRSF21 -12254.0
TFDP2 -12364.0


COPI-independent Golgi-to-ER retrograde traffic

COPI-independent Golgi-to-ER retrograde traffic
133
set COPI-independent Golgi-to-ER retrograde traffic
setSize 33
pANOVA 2.11e-08
s.dist 0.563
p.adjustANOVA 4.3e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
PLA2G4A 9180
DCTN2 9157
GALNT2 8843
BICD2 8746
CAPZA2 8597
DCTN4 8387
RAB6A 8148
CAPZA1 8135
CAPZB 8015
RAB18 7801
DYNC1I2 7735
ACTR10 7605
DCTN6 7300
ACTR1A 7002
PAFAH1B2 6942
DYNC1LI1 6941
GALNT1 6508
RAB6B 6053
DCTN3 5994
DYNLL1 5952

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PLA2G4A 9180
DCTN2 9157
GALNT2 8843
BICD2 8746
CAPZA2 8597
DCTN4 8387
RAB6A 8148
CAPZA1 8135
CAPZB 8015
RAB18 7801
DYNC1I2 7735
ACTR10 7605
DCTN6 7300
ACTR1A 7002
PAFAH1B2 6942
DYNC1LI1 6941
GALNT1 6508
RAB6B 6053
DCTN3 5994
DYNLL1 5952
RAB3GAP1 5768
PAFAH1B1 5470
DCTN1 5078
AGPAT3 4809
RAB3GAP2 4429
PAFAH1B3 4417
DYNC1LI2 4273
DYNC1I1 4187
DYNLL2 -3980
DCTN5 -4086
BICD1 -7365
DYNC1H1 -7685
PLA2G6 -12122


ER-Phagosome pathway

ER-Phagosome pathway
328
set ER-Phagosome pathway
setSize 83
pANOVA 2.17e-08
s.dist 0.355
p.adjustANOVA 4.35e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
CD36 9444
TLR2 9103
CD14 9097
TLR4 9016
TLR1 8932
TLR6 8840
LY96 8795
SNAP23 8628
PSMB7 8485
PSMD4 8402
PSME3 8251
VAMP3 8222
MYD88 8136
PSMB5 8101
CHUK 7966
PSMD6 7846
PSMD9 7620
PSMD2 7411
PSMA1 7329
PSMD1 7241

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CD36 9444
TLR2 9103
CD14 9097
TLR4 9016
TLR1 8932
TLR6 8840
LY96 8795
SNAP23 8628
PSMB7 8485
PSMD4 8402
PSME3 8251
VAMP3 8222
MYD88 8136
PSMB5 8101
CHUK 7966
PSMD6 7846
PSMD9 7620
PSMD2 7411
PSMA1 7329
PSMD1 7241
BTK 7206
PSMB3 7171
PSMA7 7096
PSMC1 7021
SEC61B 7013
PSMB6 6813
PSMF1 6659
UBB 6639
PSMC6 6635
PSMD12 6556
SEC61A1 6449
CALR 6340
PSMD11 6231
PSMA6 5970
PSMD7 5963
PSMD13 5948
SEC22B 5873
PSMD8 5757
TIRAP 5640
IKBKG 5377
PSMA2 5339
VAMP8 5218
SEC61G 4708
PSMD3 4618
UBC 4439
SEM1 4348
PDIA3 4128
PSMB2 4084
PSMD5 3426
PSMB1 3374
TAPBP 3010
PSMD14 2611
PSMC2 2598
PSMB4 2523
PSMC3 1976
PSMD10 1559
UBA52 1121
HLA-C 1018
HLA-B 649
STX4 606
PSMA4 -616
PSMC5 -863
HLA-G -2457
HLA-A -2573
PSMB8 -3076
HLA-H -3889
HLA-E -4415
PSMA3 -5285
IKBKB -5386
PSMB10 -5735
PSMA5 -6053
PSME4 -6087
B2M -6920
RPS27A -6938
PSMA8 -7606
PSMC4 -9127
PSME1 -9991
PSME2 -10336
TAP1 -10787
SEC61A2 -10798
HLA-F -11138
PSMB9 -11324
TAP2 -11807


Class I MHC mediated antigen processing & presentation

Class I MHC mediated antigen processing & presentation
188
set Class I MHC mediated antigen processing & presentation
setSize 350
pANOVA 2.99e-08
s.dist 0.172
p.adjustANOVA 5.91e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
SOCS3 9476
CD36 9444
FBXO9 9416
FBXL5 9410
FCGR1A 9323
NCF4 9268
NCF2 9190
UBE2D1 9187
KLHL2 9174
UBE2J1 9170
TLR2 9103
CD14 9097
FCGR1B 9053
CYBB 9031
TLR4 9016
TLR1 8932
TRIM71 8867
TLR6 8840
MKRN1 8817
LY96 8795

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SOCS3 9476
CD36 9444
FBXO9 9416
FBXL5 9410
FCGR1A 9323
NCF4 9268
NCF2 9190
UBE2D1 9187
KLHL2 9174
UBE2J1 9170
TLR2 9103
CD14 9097
FCGR1B 9053
CYBB 9031
TLR4 9016
TLR1 8932
TRIM71 8867
TLR6 8840
MKRN1 8817
LY96 8795
UBE2D3 8640
SNAP23 8628
FBXL19 8620
TRAF7 8612
CDC34 8611
SIAH2 8578
UBE2R2 8548
RNF130 8510
PSMB7 8485
PSMD4 8402
RNF41 8389
CTSS 8372
RNF217 8367
RNF144B 8364
UBAC1 8353
UBE2J2 8268
PSME3 8251
VAMP3 8222
MYD88 8136
ATG7 8134
SEC24D 8115
PSMB5 8101
CHUK 7966
UBE2W 7929
RNF7 7913
NEDD4L 7875
WSB1 7862
PSMD6 7846
UBA3 7767
NPEPPS 7686
ZNRF1 7675
UBE2H 7663
SEC24A 7660
PSMD9 7620
UBE2L3 7561
ELOC 7519
LRRC41 7515
FBXO7 7498
PJA2 7486
ELOB 7482
UBE2M 7477
PSMD2 7411
UBE2F 7341
SEC23A 7335
NCF1 7334
PSMA1 7329
RNF182 7310
UBE2A 7309
PSMD1 7241
BTK 7206
PSMB3 7171
PSMA7 7096
UBA1 7089
HSPA5 7029
PSMC1 7021
SEC61B 7013
UBE2B 7003
ITGB5 6923
CYBA 6922
TRIP12 6921
UBE2K 6884
CUL3 6821
PSMB6 6813
RNF123 6802
RNF19B 6764
UBE2E1 6759
FBXO11 6698
PSMF1 6659
UBB 6639
PSMC6 6635
FBXW2 6560
PSMD12 6556
SAR1B 6479
AREL1 6465
SEC61A1 6449
KBTBD7 6376
RCHY1 6374
CALR 6340
UBE3C 6282
PSMD11 6231
ASB7 6221
NEDD4 6201
FBXW11 6196
ANAPC11 6161
ITGAV 6106
PSMA6 5970
PSMD7 5963
PSMD13 5948
SEC22B 5873
MGRN1 5794
UBE2Q1 5780
PSMD8 5757
RNF111 5749
SEC13 5748
TIRAP 5640
UBE2V1 5637
FBXL13 5534
CANX 5528
FBXL4 5496
RLIM 5462
IKBKG 5377
PSMA2 5339
VAMP8 5218
KLHL5 5105
UBE2C 5101
KLHL21 5054
UBE2E3 5005
UBE2G1 4921
KEAP1 4898
HERC4 4895
ASB8 4884
HECW2 4860
FBXL20 4844
LRSAM1 4831
UBE2S 4746
SEC61G 4708
FBXO30 4683
UBE2D2 4657
PSMD3 4618
LONRF1 4539
FBXL15 4499
UBC 4439
RNF138 4382
KCTD6 4371
RNF14 4363
SEM1 4348
SKP1 4287
CTSL 4231
PDIA3 4128
UBR2 4099
PSMB2 4084
FBXL8 4021
CDC20 3998
SOCS1 3947
RNF6 3943
RBX1 3934
VHL 3674
SEC24B 3608
FBXO17 3474
UBA6 3438
PSMD5 3426
PSMB1 3374
ASB13 3324
ASB1 3319
FBXL18 3309
MRC1 3109
BLMH 3017
TAPBP 3010
RNF114 2998
UBE3A 2978
CDC26 2923
ANAPC13 2921
UBE2V2 2902
KBTBD6 2724
PSMD14 2611
PSMC2 2598
CUL2 2526
PSMB4 2523
TRIM21 2428
TRIM41 2424
SPSB1 2374
FBXO40 2368
BTBD1 2263
RBCK1 2214
UBE2O 2123
TRIM4 2088
PSMC3 1976
UBE4A 1970
UBE2N 1936
UBE3B 1890
UBE2E2 1779
TRIM9 1746
ASB9 1587
PSMD10 1559
KLHL9 1353
ASB3 1325
ITCH 1318
HECTD3 1201
UBA52 1121
SEC31A 1099
HLA-C 1018
HERC3 1012
FBXL3 1005
CUL5 834
KLHL13 702
ZBTB16 689
HLA-B 649
ZNRF2 633
STX4 606
FBXW5 265
MRC2 -165
PSMA4 -616
CDC27 -651
FBXO41 -657
PSMC5 -863
STUB1 -1032
UBOX5 -1092
RBBP6 -1125
FBXO15 -1269
FBXL12 -1321
GAN -1414
UBR4 -2086
ASB14 -2170
FZR1 -2233
FBXO6 -2300
UNKL -2338
HLA-G -2457
HECTD1 -2490
SEC24C -2569
HLA-A -2573
SMURF1 -2591
LTN1 -2597
ASB6 -2763
SIAH1 -3000
CTSV -3036
PSMB8 -3076
CUL7 -3334
TRIM11 -3671
FBXO22 -3709
HLA-H -3889
MYLIP -3991
SPSB2 -4034
KBTBD8 -4224
HLA-E -4415
UBR1 -4734
LNX1 -4796
BTRC -4924
ANAPC10 -5000
FBXO27 -5074
SH3RF1 -5151
ANAPC7 -5181
BTBD6 -5202
PSMA3 -5285
ERAP2 -5338
IKBKB -5386
DTX3L -5393
ASB4 -5604
PSMB10 -5735
HACE1 -5851
PSMA5 -6053
CDC16 -6071
PSME4 -6087
FBXL14 -6145
RNF34 -6150
KLHL11 -6286
RNF220 -6303
FBXO10 -6427
FBXW7 -6600
ANAPC4 -6644
FBXL16 -6648
ASB16 -6665
TRIM36 -6670
UFL1 -6680
B2M -6920
RPS27A -6938
RNF25 -7289
FBXW9 -7360
ERAP1 -7370
ANAPC2 -7407
UBA7 -7558
PSMA8 -7606
LRR1 -7643
HUWE1 -7977
UBE2G2 -8035
SKP2 -8279
UBA5 -8300
FBXO2 -8324
FBXW12 -8358
KLHL42 -8367
TRIM37 -8494
TPP2 -8977
HECTD2 -9020
PSMC4 -9127
DET1 -9199
FBXL22 -9210
CCNF -9262
HERC1 -9297
THOP1 -9447
TRIM69 -9591
PJA1 -9611
LNPEP -9618
FBXO44 -9627
LMO7 -9709
RNF115 -9777
PSME1 -9991
FBXW8 -10013
WWP1 -10106
RNF19A -10197
PSME2 -10336
SMURF2 -10340
TRIM39 -10438
RNF126 -10545
FBXO32 -10607
HERC2 -10658
KLHL25 -10671
UBE3D -10777
TAP1 -10787
FBXO21 -10790
SEC61A2 -10798
UBE2Z -10912
ANAPC5 -10967
DZIP3 -11017
MIB2 -11073
GLMN -11075
HLA-F -11138
UBE2D4 -11203
UBE2L6 -11293
CDC23 -11304
PSMB9 -11324
CUL1 -11330
KLHL22 -11407
RNF4 -11467
KLHL20 -11483
TRIM32 -11493
KCTD7 -11546
UBE2Q2 -11554
TRAIP -11615
KLHL3 -11635
FBXW4 -11757
TAP2 -11807
FBXO4 -11843
RNF213 -11905
FBXO31 -11953
ANAPC1 -11962
ASB2 -11978
ARIH2 -12090
MEX3C -12144
HERC6 -12205
HERC5 -12225
CBLB -12303


Cellular response to hypoxia

Cellular response to hypoxia
168
set Cellular response to hypoxia
setSize 72
pANOVA 3.43e-08
s.dist 0.376
p.adjustANOVA 6.69e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
UBE2D1 9187
UBE2D3 8640
PSMB7 8485
PSMD4 8402
PSME3 8251
PSMB5 8101
ARNT 8047
EPAS1 7886
PSMD6 7846
PSMD9 7620
ELOC 7519
ELOB 7482
VEGFA 7467
HIF1A 7436
PSMD2 7411
HIGD1A 7394
PSMA1 7329
PSMD1 7241
PSMB3 7171
PSMA7 7096

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
UBE2D1 9187
UBE2D3 8640
PSMB7 8485
PSMD4 8402
PSME3 8251
PSMB5 8101
ARNT 8047
EPAS1 7886
PSMD6 7846
PSMD9 7620
ELOC 7519
ELOB 7482
VEGFA 7467
HIF1A 7436
PSMD2 7411
HIGD1A 7394
PSMA1 7329
PSMD1 7241
PSMB3 7171
PSMA7 7096
PSMC1 7021
PSMB6 6813
PSMF1 6659
UBB 6639
PSMC6 6635
EGLN1 6604
PSMD12 6556
CITED2 6457
PSMD11 6231
EP300 6129
PSMA6 5970
PSMD7 5963
PSMD13 5948
PSMD8 5757
PSMA2 5339
UBE2D2 4657
PSMD3 4618
UBC 4439
SEM1 4348
PSMB2 4084
RBX1 3934
VHL 3674
EGLN2 3578
PSMD5 3426
CREBBP 3423
PSMB1 3374
PSMD14 2611
PSMC2 2598
CUL2 2526
PSMB4 2523
PSMC3 1976
PSMD10 1559
UBA52 1121
EGLN3 -437
PSMA4 -616
PSMC5 -863
HIF3A -2519
PSMB8 -3076
HIF1AN -4510
PSMA3 -5285
PSMB10 -5735
PSMA5 -6053
PSME4 -6087
RPS27A -6938
WTIP -7208
PSMA8 -7606
AJUBA -7927
PSMC4 -9127
PSME1 -9991
PSME2 -10336
LIMD1 -10791
PSMB9 -11324


Detoxification of Reactive Oxygen Species

Detoxification of Reactive Oxygen Species
279
set Detoxification of Reactive Oxygen Species
setSize 32
pANOVA 3.64e-08
s.dist 0.562
p.adjustANOVA 6.98e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
PRDX3 9366
GPX1 9314
NCF4 9268
GSR 9235
NCF2 9190
CAT 9123
CYBB 9031
ERO1A 8943
PRDX6 8937
PRDX5 8531
P4HB 8440
TXN 8285
TXNRD1 8192
TXNRD2 7526
NCF1 7334
PRDX1 7030
CYBA 6922
TXN2 4651
SOD2 4390
ATOX1 4338

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PRDX3 9366
GPX1 9314
NCF4 9268
GSR 9235
NCF2 9190
CAT 9123
CYBB 9031
ERO1A 8943
PRDX6 8937
PRDX5 8531
P4HB 8440
TXN 8285
TXNRD1 8192
TXNRD2 7526
NCF1 7334
PRDX1 7030
CYBA 6922
TXN2 4651
SOD2 4390
ATOX1 4338
PRDX2 3428
NUDT2 2988
CCS 1538
NOX5 1175
NOX4 1114
ATP7A 694
GPX3 680
GSTP1 135
CYCS -1334
GPX2 -3533
SOD1 -4862
GPX7 -8901


Cargo recognition for clathrin-mediated endocytosis

Cargo recognition for clathrin-mediated endocytosis
148
set Cargo recognition for clathrin-mediated endocytosis
setSize 90
pANOVA 4.34e-08
s.dist 0.334
p.adjustANOVA 8.21e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
VAMP7 9499
GRB2 9304
ITSN1 9289
AGFG1 9211
PICALM 9022
CLTC 9000
CLTCL1 8965
TGFA 8889
TGOLN2 8714
AP2M1 8627
ARRB2 8490
CLTA 8376
VAMP3 8222
EGF 8179
REPS2 8154
DAB2 8112
EPN1 8045
TOR1A 8033
AP2S1 8026
FCHO2 7807

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
VAMP7 9499
GRB2 9304
ITSN1 9289
AGFG1 9211
PICALM 9022
CLTC 9000
CLTCL1 8965
TGFA 8889
TGOLN2 8714
AP2M1 8627
ARRB2 8490
CLTA 8376
VAMP3 8222
EGF 8179
REPS2 8154
DAB2 8112
EPN1 8045
TOR1A 8033
AP2S1 8026
FCHO2 7807
SH3GL1 7625
CBL 7480
AP2A2 7257
IGF2R 7149
AP2A1 6832
UBB 6639
GRK3 6593
COPS7A 6590
NEDD8 6482
LDLR 6183
SH3KBP1 6173
STAM2 6159
COPS2 6139
CLTB 6084
GRK2 6068
COPS3 6005
AREG 5977
UBQLN2 5939
SCARB2 5255
VAMP8 5218
UBQLN1 5108
ITSN2 5060
SYT1 5056
HBEGF 5013
HGS 4513
UBC 4439
COPS5 4361
EPS15 4138
EPS15L1 3655
STON2 3569
NECAP2 3387
VAMP4 3191
KIAA0319 3163
EPGN 2662
STON1 2574
CFTR 2416
NECAP1 2220
ARRB1 1998
EREG 1888
COPS4 1776
COPS6 1637
TFRC 1524
LRP2 1307
STAM 1285
UBA52 1121
TF 1102
SYT2 461
AVPR2 291
TOR1B -2136
FCHO1 -2392
AP2B1 -2709
EPN2 -4100
GPS1 -4517
CD4 -5406
SYT11 -6763
RPS27A -6938
REPS1 -7137
M6PR -8519
COPS8 -8755
AAK1 -9190
LDLRAP1 -9326
COPS7B -9775
IL7R -10546
DVL2 -11152
CD3D -11401
CD3G -11526
FZD4 -11650
SLC2A8 -11749
VAMP2 -11779
ADRB2 -11892


Signaling by Nuclear Receptors

Signaling by Nuclear Receptors
1122
set Signaling by Nuclear Receptors
setSize 217
pANOVA 5.11e-08
s.dist 0.215
p.adjustANOVA 9.54e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
CTSD 9433
H2AJ 9374
GNG10 9349
H2BC21 9283
FKBP5 9091
AGO4 9070
H2BC12 9051
CARM1 9020
MAPK3 8953
ALDH1A2 8914
TGFA 8889
GNG5 8815
FOXO3 8682
H3-3A 8661
ZDHHC7 8636
TLE3 8558
GNB1 8294
SP1 8193
EGF 8179
GNB2 8141

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CTSD 9433.0
H2AJ 9374.0
GNG10 9349.0
H2BC21 9283.0
FKBP5 9091.0
AGO4 9070.0
H2BC12 9051.0
CARM1 9020.0
MAPK3 8953.0
ALDH1A2 8914.0
TGFA 8889.0
GNG5 8815.0
FOXO3 8682.0
H3-3A 8661.0
ZDHHC7 8636.0
TLE3 8558.0
GNB1 8294.0
SP1 8193.0
EGF 8179.0
GNB2 8141.0
GNAI2 8075.0
H2BC5 8003.0
NCOR2 7985.0
GNAI3 7953.0
H2AC6 7934.0
H2BC11 7912.0
KDM4B 7911.0
TBL1X 7887.0
SPHK1 7657.0
TFF3 7621.0
POLR2E 7563.0
RUNX1 7529.0
RXRA 7495.0
MAPK1 7493.0
NR1H2 7415.0
H2BC4 7389.0
PLTP 7338.0
GNB4 7336.0
DLD 7303.0
H2BC17 7285.0
SRF 7079.0
GTF2A2 7066.0
H3C15 6699.5
POLR2J 6671.0
SREBF1 6539.0
GNG11 6495.0
RDH11 6466.0
USF2 6440.0
RARA 6429.0
EEPD1 6251.0
DHRS9 6236.0
PDPK1 6136.0
EP300 6129.0
ABCA1 6109.0
H2AZ1 6036.0
FABP5 6021.0
IGF1R 5990.0
AREG 5977.0
PDK4 5953.0
NCOR1 5887.0
AGO1 5654.0
FOS 5460.0
GTF2F2 5434.0
H2BC9 5394.0
NRAS 5363.0
S1PR3 5323.0
H2BC15 5312.0
POLR2L 5305.0
STAG2 5301.0
CPT1A 5077.0
KDM1B 5073.0
HBEGF 5013.0
PIK3R2 5010.0
H2AC20 4972.0
GTF2F1 4951.0
USF1 4829.0
PPID 4695.0
HDAC3 4673.0
PIK3CA 4629.0
NRIP1 4609.0
POLR2F 4604.0
TBL1XR1 4556.0
CAV2 4516.0
NCOA1 4483.0
PTK2 4462.0
KCTD6 4371.0
GNG8 4296.0
PDHX 4282.0
PDK1 4249.0
PDHB 4233.0
SHC1 4161.0
PTGES3 4125.0
SCD 4026.0
MMP7 3918.0
DHRS4 3786.0
JUN 3722.0
KRAS 3702.0
STRN 3695.0
AKT1 3614.0
NCOA3 3522.0
POLR2G 3508.0
CREBBP 3423.0
GNAI1 3329.0
PDK3 3252.0
ZNF217 3232.0
ABCG8 3056.0
CETP 3003.0
AGO2 2995.0
GTF2A1 2713.0
EPGN 2662.0
MYC 2304.0
ATF2 2085.0
CBFB 2078.0
CAV1 1969.0
EREG 1888.0
RAD21 1709.0
MMP9 1690.0
POLR2C 1616.0
JUND 1549.0
POU2F1 1537.0
FOSB 1368.0
HSP90AA1 1326.0
KAT5 1314.0
NCOA2 1092.0
ELK1 1040.0
GNG3 890.0
FKBP4 832.0
SMC1A 613.0
RDH5 591.0
HDAC1 587.0
YY1 537.0
GNB5 512.0
AKT2 433.0
POLR2I 396.0
MYB 302.0
APOE 218.0
CHD1 69.0
KDM4A -20.0
APOD -426.0
FASN -690.0
GPS2 -889.0
AGO3 -1011.0
XPO1 -1185.0
H2AZ2 -1209.0
CREB1 -1378.0
CRABP2 -1447.0
POLR2K -1783.0
SMC3 -1975.0
NOS3 -2059.0
CALM1 -2081.0
GNG4 -2154.0
GNB3 -2397.0
KAT2B -2414.0
POLR2B -2523.0
POLR2H -2942.0
POLR2A -3092.0
RXRB -3276.0
HRAS -3382.0
DLAT -3526.0
NR1H3 -3597.0
PLIN1 -3785.0
UHMK1 -3877.0
CDK9 -3927.0
KANK1 -3964.0
MYLIP -3991.0
POLR2D -4024.0
MED1 -4036.0
TNRC6B -4518.0
PDHA1 -4581.0
CPT1B -4584.0
RDH10 -4665.0
BCL2 -4704.0
RARG -5153.0
GNG7 -5198.0
TNRC6A -5613.0
STAG1 -6347.0
PPARD -6394.0
ZDHHC21 -6453.0
H2BU1 -6555.0
HSP90AB1 -6863.0
KPNA2 -6910.0
GREB1 -6937.0
CCND1 -6970.0
CXXC5 -7037.0
ALDH8A1 -7123.0
PPP5C -7462.0
GNG2 -7795.0
ABCG1 -7961.0
PDK2 -8047.0
CDKN1B -8207.0
RDH16 -8604.0
SRC -8820.0
ESR1 -9122.0
TBP -9167.0
PRMT1 -9229.0
ESR2 -9250.0
KDM1A -9430.0
CCNT1 -9469.0
PIK3R1 -9505.0
DDX5 -9843.0
EBAG9 -10187.0
GPAM -10241.0
AXIN1 -10285.0
RDH14 -10397.0
RDH13 -10602.0
PRKCZ -11629.0
ALDH1A1 -11765.0
TNRC6C -11828.0
AKT3 -11849.0
MOV10 -11991.0
PIK3R3 -12015.0
DHRS3 -12084.0
GNGT2 -12086.0
KDM3A -12102.0
AKR1C3 -12104.0
GATA3 -12191.0
ARL4C -12296.0


COPII-mediated vesicle transport

COPII-mediated vesicle transport
135
set COPII-mediated vesicle transport
setSize 65
pANOVA 5.29e-08
s.dist 0.39
p.adjustANOVA 9.67e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
F5 9485
SERPINA1 9168
RAB1A 9052
CTSZ 8975
TGFA 8889
NSF 8829
RAB1B 8313
SEC24D 8115
TRAPPC1 7806
CNIH1 7779
SEC24A 7660
SEC23A 7335
STX5 7166
TFG 7160
TRAPPC3 7114
MCFD2 7099
LMAN2 7080
F8 7022
LMAN2L 6937
PPP6C 6819

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
F5 9485
SERPINA1 9168
RAB1A 9052
CTSZ 8975
TGFA 8889
NSF 8829
RAB1B 8313
SEC24D 8115
TRAPPC1 7806
CNIH1 7779
SEC24A 7660
SEC23A 7335
STX5 7166
TFG 7160
TRAPPC3 7114
MCFD2 7099
LMAN2 7080
F8 7022
LMAN2L 6937
PPP6C 6819
GORASP1 6606
SAR1B 6479
PREB 6368
COL7A1 6304
GOLGA2 6203
TMED2 6052
AREG 5977
SEC22B 5873
CD59 5859
SEC13 5748
TRAPPC9 5333
PPP6R1 5263
YKT6 5205
TRAPPC5 5191
SEC16A 4619
USO1 4154
TRAPPC6B 4147
NAPG 4139
SEC24B 3608
SCFD1 3525
PPP6R3 3261
CSNK1D 2390
CTSC 2326
NAPA 1432
SEC31A 1099
CNIH2 654
SEC16B 330
TMED10 323
TBC1D20 -18
SEC23IP -468
BET1 -594
GOSR2 -1456
TRAPPC2L -2299
SEC24C -2569
NAPB -2780
SEC22C -4248
SEC22A -5052
ANKRD28 -6250
TRAPPC4 -6712
TRAPPC2 -8704
CNIH3 -9011
TRAPPC10 -9369
LMAN1 -10630
TRAPPC6A -10917
STX17 -11006


RUNX1 regulates transcription of genes involved in differentiation of HSCs

RUNX1 regulates transcription of genes involved in differentiation of HSCs
928
set RUNX1 regulates transcription of genes involved in differentiation of HSCs
setSize 83
pANOVA 5.32e-08
s.dist 0.345
p.adjustANOVA 9.67e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2AJ 9374
H2BC21 9283
H2BC12 9051
SPI1 8891
H3-3A 8661
PSMB7 8485
GATA1 8410
PSMD4 8402
LMO2 8307
PSME3 8251
PSMB5 8101
H2BC5 8003
H2AC6 7934
H2BC11 7912
PSMD6 7846
PSMD9 7620
RUNX1 7529
PSMD2 7411
H2BC4 7389
PSMA1 7329

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2AJ 9374.0
H2BC21 9283.0
H2BC12 9051.0
SPI1 8891.0
H3-3A 8661.0
PSMB7 8485.0
GATA1 8410.0
PSMD4 8402.0
LMO2 8307.0
PSME3 8251.0
PSMB5 8101.0
H2BC5 8003.0
H2AC6 7934.0
H2BC11 7912.0
PSMD6 7846.0
PSMD9 7620.0
RUNX1 7529.0
PSMD2 7411.0
H2BC4 7389.0
PSMA1 7329.0
H2BC17 7285.0
PSMD1 7241.0
PSMB3 7171.0
PSMA7 7096.0
PSMC1 7021.0
PSMB6 6813.0
H3C15 6699.5
PSMF1 6659.0
UBB 6639.0
PSMC6 6635.0
PSMD12 6556.0
TAL1 6518.0
PSMD11 6231.0
H2AZ1 6036.0
PSMA6 5970.0
PSMD7 5963.0
PSMD13 5948.0
PSMD8 5757.0
H2BC9 5394.0
PSMA2 5339.0
H2BC15 5312.0
CDK7 5211.0
H2AC20 4972.0
PSMD3 4618.0
UBC 4439.0
SEM1 4348.0
PSMB2 4084.0
PSMD5 3426.0
PSMB1 3374.0
PSMD14 2611.0
PSMC2 2598.0
PSMB4 2523.0
CBFB 2078.0
PSMC3 1976.0
PSMD10 1559.0
ITCH 1318.0
UBA52 1121.0
CCNH 774.0
MYB 302.0
ABL1 226.0
PSMA4 -616.0
PSMC5 -863.0
H2AZ2 -1209.0
TCF12 -1233.0
PSMB8 -3076.0
TP73 -4754.0
PSMA3 -5285.0
PSMB10 -5735.0
PSMA5 -6053.0
PSME4 -6087.0
H2BU1 -6555.0
RPS27A -6938.0
TCF3 -7215.0
PSMA8 -7606.0
MNAT1 -8687.0
PSMC4 -9127.0
GATA2 -9800.0
PSME1 -9991.0
LDB1 -10303.0
PSME2 -10336.0
KMT2A -10725.0
PSMB9 -11324.0
GATA3 -12191.0


Cellular responses to stress

Cellular responses to stress
170
set Cellular responses to stress
setSize 500
pANOVA 5.6e-08
s.dist 0.142
p.adjustANOVA 9.93e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
H1-2 9491
GRB10 9439
LAMTOR1 9411
H2AJ 9374
PRDX3 9366
LMNB1 9345
GPX1 9314
ATP6V1A 9302
H2BC21 9283
NCF4 9268
ATP6V0D1 9245
GSR 9235
NCF2 9190
UBE2D1 9187
DCTN2 9157
ATP6V0C 9127
CAT 9123
MAPK14 9104
FKBP5 9091
AGO4 9070

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H1-2 9491.0
GRB10 9439.0
LAMTOR1 9411.0
H2AJ 9374.0
PRDX3 9366.0
LMNB1 9345.0
GPX1 9314.0
ATP6V1A 9302.0
H2BC21 9283.0
NCF4 9268.0
ATP6V0D1 9245.0
GSR 9235.0
NCF2 9190.0
UBE2D1 9187.0
DCTN2 9157.0
ATP6V0C 9127.0
CAT 9123.0
MAPK14 9104.0
FKBP5 9091.0
AGO4 9070.0
ATP6V1B2 9057.0
H2BC12 9051.0
ATP6V1D 9047.0
YWHAE 9045.0
PHC2 9043.0
CYBB 9031.0
ANAPC15 8968.0
MAPK3 8953.0
ERO1A 8943.0
PRDX6 8937.0
MAP2K6 8887.0
CDKN2B 8836.0
NUP58 8820.0
RRAGD 8753.0
MAP2K3 8748.0
RB1 8707.0
H3-3A 8661.0
UBE2D3 8640.0
E2F2 8601.0
ATP6V0B 8598.0
CAPZA2 8597.0
ATP6V0E1 8596.0
KDM6B 8577.0
ATP6V1C1 8539.0
PRDX5 8531.0
LAMTOR5 8498.0
PSMB7 8485.0
EIF2AK1 8482.0
TFDP1 8470.0
P4HB 8440.0
MAP4K4 8425.0
PSMD4 8402.0
DCTN4 8387.0
MAPKAPK3 8382.0
BAG4 8328.0
TXN 8285.0
PSME3 8251.0
SP1 8193.0
TXNRD1 8192.0
HSBP1 8173.0
CAPZA1 8135.0
PSMB5 8101.0
STAT3 8098.0
ETS2 8092.0
HSPA1A 8071.0
DNAJB6 8066.0
ATP6V1H 8064.0
ARNT 8047.0
ATP6V1E1 8035.0
CAPZB 8015.0
H2BC5 8003.0
CEBPB 7997.0
H2AC6 7934.0
NUP214 7921.0
H2BC11 7912.0
EPAS1 7886.0
AKT1S1 7865.0
CDKN2D 7853.0
PSMD6 7846.0
DYNC1I2 7735.0
DNAJC7 7701.0
RPS6KA1 7695.0
MAP3K5 7682.0
RHEB 7669.0
PSMD9 7620.0
ACTR10 7605.0
LAMTOR3 7574.0
LAMTOR2 7567.0
TXNRD2 7526.0
ELOC 7519.0
MAPK1 7493.0
H1-0 7492.0
ELOB 7482.0
VEGFA 7467.0
HIF1A 7436.0
PSMD2 7411.0
HIGD1A 7394.0
H2BC4 7389.0
BMT2 7350.0
NCF1 7334.0
PSMA1 7329.0
DCTN6 7300.0
H2BC17 7285.0
PSMD1 7241.0
TCIRG1 7188.0
RPL26L1 7176.0
PSMB3 7171.0
PSMA7 7096.0
HSPA2 7081.0
PRDX1 7030.0
HSPA5 7029.0
PSMC1 7021.0
ACTR1A 7002.0
DYNC1LI1 6941.0
CYBA 6922.0
VCP 6886.0
MAP2K4 6866.0
PSMB6 6813.0
CDKN2C 6811.0
UBE2E1 6759.0
EIF2S3 6747.0
H3C15 6699.5
PSMF1 6659.0
E2F3 6650.0
UBB 6639.0
PSMC6 6635.0
GSK3B 6634.0
EGLN1 6604.0
PSMD12 6556.0
IGFBP7 6545.0
HSPA6 6514.0
HSPA1B 6470.0
CITED2 6457.0
BAG1 6396.0
E2F1 6343.0
NFKB1 6277.0
KPTN 6265.0
RRAGA 6244.0
ATF4 6237.0
PSMD11 6231.0
EIF2S2 6175.0
ANAPC11 6161.0
EP300 6129.0
HSF1 6063.0
H2AZ1 6036.0
DCTN3 5994.0
PPP1R15A 5981.0
PSMA6 5970.0
PSMD7 5963.0
DYNLL1 5952.0
PSMD13 5948.0
ATP6V1F 5878.0
PSMD8 5757.0
SEC13 5748.0
ATP6V1E2 5730.0
AGO1 5654.0
FNIP1 5603.0
DNAJA2 5589.0
CEBPG 5466.0
FOS 5460.0
CBX8 5448.0
DNAJA1 5425.0
RPS9 5421.0
H2BC9 5394.0
UBN1 5358.0
HSPA4 5350.0
PSMA2 5339.0
H2BC15 5312.0
RAE1 5164.0
CCNE2 5143.0
UBE2C 5101.0
DCTN1 5078.0
TERF2IP 5040.0
H2AC20 4972.0
RRAGC 4954.0
ID1 4927.0
DDIT3 4906.0
AR 4840.0
UBE2S 4746.0
UBE2D2 4657.0
TXN2 4651.0
PSMD3 4618.0
TINF2 4592.0
NUP50 4521.0
CDKN1A 4511.0
NPRL3 4510.0
RPL3L 4503.0
LAMTOR4 4441.0
UBC 4439.0
ERF 4400.0
SOD2 4390.0
SEM1 4348.0
ATOX1 4338.0
MAPK10 4325.0
MDM2 4312.0
EIF2S1 4279.0
DYNC1LI2 4273.0
DYNC1I1 4187.0
PTGES3 4125.0
PSMB2 4084.0
MAPKAPK2 4054.0
CBX6 4033.0
RBX1 3934.0
ATP6V1G1 3931.0
MAPK11 3826.0
JUN 3722.0
MINK1 3687.0
VHL 3674.0
FLCN 3622.0
EGLN2 3578.0
RNF2 3513.0
PRDX2 3428.0
PSMD5 3426.0
CREBBP 3423.0
MIOS 3378.0
PSMB1 3374.0
DEDD2 3327.0
SESN2 3311.0
HSPA1L 3102.0
NUP98 3101.0
RPS6KA2 3087.0
NUP37 3074.0
VENTX 3057.0
NUDT2 2988.0
RPS6KA3 2973.0
CDC26 2923.0
SLC38A9 2807.0
RPS19BP1 2709.0
PSMD14 2611.0
PSMC2 2598.0
CUL2 2526.0
PSMB4 2523.0
NBN 2267.0
HSPA12B 2254.0
CBX4 2222.0
H1-4 2207.0
MRPL18 2144.0
ATF2 2085.0
RPS27L 2061.0
PSMC3 1976.0
CAMK2G 1921.0
CXCL8 1729.0
CCNA2 1685.0
MAP2K7 1654.0
PSMD10 1559.0
CCS 1538.0
HSP90AA1 1326.0
KAT5 1314.0
NOX5 1175.0
WDR24 1150.0
UBA52 1121.0
NOX4 1114.0
FKBP4 832.0
NUP62 769.0
ATP7A 694.0
GPX3 680.0
CCNA1 585.0
NR3C1 511.0
RPS4Y1 424.0
MLST8 376.0
GSTP1 135.0
HMGA1 117.0
DEPDC5 102.0
EIF2AK4 41.0
RPL36AL 32.0
RPLP1 19.0
HIKESHI -103.0
RPS24 -263.0
FAU -362.0
EGLN3 -437.0
PSMA4 -616.0
CDC27 -651.0
RRAGB -713.0
RANBP2 -820.0
PSMC5 -863.0
DNAJA4 -881.0
RPL15 -963.0
RPLP0 -1000.0
AGO3 -1011.0
HSPA13 -1157.0
RPL8 -1187.0
H2AZ2 -1209.0
MDM4 -1230.0
ST13 -1254.0
CYCS -1334.0
MAPK7 -1337.0
RPS26 -1430.0
RPL28 -1462.0
RPL22L1 -1619.0
RPS13 -1749.0
HSPA12A -1760.0
RELA -1803.0
RBBP4 -1870.0
RPL9 -1872.0
RPL7 -1955.0
RPS8 -2083.0
STIP1 -2094.0
ANAPC16 -2123.0
ATP6V1C2 -2219.0
FZR1 -2233.0
SUZ12 -2409.0
HIF3A -2519.0
RPL27 -2855.0
FNIP2 -2881.0
HSPA4L -2948.0
RPL39 -3006.0
NUP85 -3049.0
PSMB8 -3076.0
BAG3 -3170.0
IMPACT -3210.0
RPL23 -3314.0
RPL6 -3354.0
RPL13 -3431.0
GPX2 -3533.0
RPL4 -3582.0
TERF1 -3601.0
RPL29 -3611.0
RPL7A -3665.0
RPS15 -3673.0
RPL37A -3946.0
DYNLL2 -3980.0
RING1 -4063.0
RPS21 -4079.0
DCTN5 -4086.0
SIRT1 -4197.0
POT1 -4355.0
TERF2 -4464.0
RPS2 -4499.0
HIF1AN -4510.0
TNRC6B -4518.0
RPL31 -4541.0
CBX2 -4617.0
RPS16 -4669.0
RPS3A -4694.0
RPS28 -4713.0
RPL5 -4728.0
RPL22 -4740.0
SOD1 -4862.0
BAG5 -4887.0
DNAJC2 -4961.0
RPS7 -4968.0
ANAPC10 -5000.0
CDK2 -5006.0
RPL18 -5080.0
EEF1A1 -5087.0
ANAPC7 -5181.0
CDKN2A -5236.0
PSMA3 -5285.0
RPL36 -5287.0
ATF5 -5305.0
SZT2 -5322.0
RPL17 -5431.0
RPS14 -5463.0
NUP42 -5564.0
TNRC6A -5613.0
DNAJB1 -5672.0
RPS5 -5691.0
PSMB10 -5735.0
RPS15A -5742.0
RPS10 -5793.0
RPL24 -5799.0
SCMH1 -5839.0
RPL38 -5840.0
TRIB3 -5843.0
RPS3 -5914.0
RPS12 -5987.0
RPL35A -6015.0
PSMA5 -6053.0
SEH1L -6069.0
RPL18A -6070.0
CDC16 -6071.0
PSME4 -6087.0
RPS6 -6160.0
RPS17 -6247.0
RPL27A -6257.0
RPL11 -6261.0
RPL19 -6281.0
RPS4X -6285.0
RPS23 -6292.0
RPA2 -6306.0
NUP153 -6321.0
RPSA -6323.0
RPS25 -6365.0
RPL37 -6375.0
RPL21 -6458.0
CDK6 -6465.0
RLN1 -6482.0
RPL10 -6534.0
EP400 -6550.0
H2BU1 -6555.0
RPL26 -6612.0
ANAPC4 -6644.0
RPL10A -6686.0
RPL32 -6709.0
RPL14 -6710.0
RPL34 -6802.0
HSP90AB1 -6863.0
RPL41 -6866.0
RPS27A -6938.0
RPS19 -6965.0
RPL30 -7020.0
TPR -7028.0
RPL12 -7053.0
MAPK9 -7068.0
RPLP2 -7087.0
POM121C -7188.0
WTIP -7208.0
RPS11 -7243.0
RAD50 -7373.0
RPL36A -7376.0
ANAPC2 -7407.0
PSMA8 -7606.0
DYNC1H1 -7685.0
RPS18 -7744.0
NUP133 -7762.0
ACD -7800.0
MRE11 -7923.0
AJUBA -7927.0
RPS29 -7940.0
BAG2 -7997.0
RPL35 -8092.0
PHC3 -8152.0
CDKN1B -8207.0
RPL13A -8212.0
HSPA7 -8236.0
POM121 -8299.0
ASNS -8316.0
HDAC6 -8337.0
MAPKAPK5 -8364.0
AAAS -8389.0
PHC1 -8402.0
NUP54 -8479.0
EHMT2 -8558.0
RPL3 -8561.0
EHMT1 -8692.0
RPL39L -8805.0
SH3BP4 -8881.0
RPS20 -8886.0
GPX7 -8901.0
RPA3 -8911.0
SESN1 -8962.0
PSMC4 -9127.0
WDR59 -9240.0
EED -9348.0
HSPA14 -9380.0
HSPH1 -9407.0
MAPK8 -9428.0
ATP6V1G2 -9515.0
NUP43 -9517.0
RPL23A -9567.0
HIRA -9628.0
ATF3 -9677.0
EZH2 -9741.0
RPS27 -9756.0
MTOR -9767.0
HSPA9 -9780.0
ASF1A -9781.0
BMI1 -9829.0
PSME1 -9991.0
SERPINH1 -10121.0
CCAR2 -10156.0
NUP155 -10233.0
PSME2 -10336.0
ATR -10354.0
GCN1 -10372.0
NUP107 -10421.0
RPTOR -10464.0
NUP160 -10557.0
CABIN1 -10590.0
NUP35 -10611.0
NR3C2 -10625.0
ITFG2 -10719.0
NUP210 -10726.0
LIMD1 -10791.0
TP53 -10893.0
HSPA8 -10922.0
C12orf66 -10960.0
ANAPC5 -10967.0
ATM -11148.0
CDK4 -11256.0
CDC23 -11304.0
NUP205 -11321.0
PSMB9 -11324.0
ETS1 -11386.0
NUP88 -11397.0
ATP6V0E2 -11555.0
NPRL2 -11604.0
NUP93 -11620.0
NUP188 -11624.0
TNIK -11674.0
CCNE1 -11707.0
CAMK2D -11816.0
TNRC6C -11828.0
ANAPC1 -11962.0
MOV10 -11991.0
RPA1 -12004.0
RBBP7 -12155.0
NDC1 -12173.0
TNFRSF21 -12254.0
TFDP2 -12364.0


The citric acid (TCA) cycle and respiratory electron transport

The citric acid (TCA) cycle and respiratory electron transport
1228
set The citric acid (TCA) cycle and respiratory electron transport
setSize 172
pANOVA 5.61e-08
s.dist 0.24
p.adjustANOVA 9.93e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
BSG 9172
ME1 8892
SLC16A3 8783
ETFA 8658
LDHA 8637
NDUFB3 8430
SDHC 8390
NDUFB9 8237
NDUFAF1 8167
UQCRH 8073
ETFDH 8052
UQCRC1 7859
COX7A2L 7719
ETFB 7688
ATP5PD 7637
SDHB 7587
NDUFB1 7578
SUCLA2 7558
ATP5PB 7551
RXRA 7495

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
BSG 9172
ME1 8892
SLC16A3 8783
ETFA 8658
LDHA 8637
NDUFB3 8430
SDHC 8390
NDUFB9 8237
NDUFAF1 8167
UQCRH 8073
ETFDH 8052
UQCRC1 7859
COX7A2L 7719
ETFB 7688
ATP5PD 7637
SDHB 7587
NDUFB1 7578
SUCLA2 7558
ATP5PB 7551
RXRA 7495
DLD 7303
NDUFAF3 6981
SDHD 6963
ME2 6915
UQCR11 6907
TIMMDC1 6822
ATP5F1C 6687
COX8A 6611
ATP5MF 6519
ATP5F1B 6497
NDUFA4 6459
ATP5F1A 6441
ATP5PF 6373
NDUFS1 6348
UQCRFS1 6325
COX5B 6207
NDUFS5 6178
COX5A 6168
ATP5F1E 6142
NDUFC2 6093
NDUFS2 6080
NDUFA6 6009
SUCLG1 5961
PDK4 5953
ATP5MC3 5906
UQCRC2 5852
NDUFB10 5812
NDUFAB1 5759
NDUFA1 5718
COX6B1 5667
NDUFA7 5623
ATP5MG 5512
GSTZ1 5438
NDUFC1 5343
NDUFV3 5214
HAGH 5104
COX6A1 5095
NDUFA2 4966
ECSIT 4918
NDUFA8 4804
ATP5PO 4794
MPC2 4555
NDUFB4 4553
COX7B 4465
SLC16A1 4455
NNT 4407
TACO1 4406
UQCR10 4378
VDAC1 4347
NDUFV2 4288
PDHX 4282
PDK1 4249
NDUFA13 4244
PDHB 4233
NDUFB6 4218
ACO2 4209
MDH2 4207
COX4I1 4191
NDUFS6 4155
OGDH 4136
COQ10B 3989
NDUFS4 3986
NDUFB5 3892
UQCRB 3834
CS 3688
SURF1 3532
IDH3G 3314
PDK3 3252
CYC1 3047
ATP5F1D 2968
UQCRQ 2960
ATP5MC2 2956
FH 2879
NDUFAF7 2726
ATP5ME 2664
NDUFB7 2292
NDUFAF2 2133
NDUFS7 2118
SLC16A8 1608
NDUFA11 1458
NDUFB11 1172
NDUFB8 965
UCP2 913
NDUFS3 884
MT-ND4 840
COX6C 706
MT-CO1 684
COX7C 564
NDUFA3 503
MT-ND6 459
FAHD1 174
COX16 132
NDUFS8 81
MT-CO2 48
MT-CO3 40
ACAD9 -879
MPC1 -1097
CYCS -1334
COX14 -1496
IDH3B -1504
NDUFA12 -1728
MT-ATP6 -2096
MT-ND5 -2166
MT-CYB -2254
NDUFAF6 -2331
LDHAL6A -2551
MT-ATP8 -3067
IDH2 -3102
DLAT -3526
MT-ND1 -3616
MT-ND3 -3649
GLO1 -3721
PDP1 -4260
SCO2 -4351
SLC25A27 -4356
NDUFB2 -4446
PDHA1 -4581
SLC25A14 -4642
NDUFA5 -4723
COX20 -5018
ADHFE1 -5216
SDHA -5579
D2HGDH -5760
SUCLG2 -5783
COX18 -6126
PPARD -6394
MT-ND2 -6560
COX19 -6882
NDUFA10 -6994
DMAC2L -7274
PDPR -7326
ATP5MC1 -7616
PDK2 -8047
TMEM126B -8346
NDUFA9 -8864
DLST -8906
IDH3A -9280
NDUFAF5 -9499
SCO1 -9819
L2HGDH -9902
PM20D1 -9905
LDHB -9933
ME3 -10048
NDUFAF4 -10063
LRPPRC -10081
UCP3 -10214
TRAP1 -10796
PDP2 -11231
COQ10A -11405
NDUFV1 -11466
COX11 -11539
NUBPL -11628


Infectious disease

Infectious disease
525
set Infectious disease
setSize 724
pANOVA 7.34e-08
s.dist 0.117
p.adjustANOVA 1.28e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
WASF1 9520
HRH2 9466
CD163 9462
PRKACA 9429
GGT1 9426
ADM 9378
GNG10 9349
GPR27 9340
FCGR1A 9323
GRB2 9304
IMPDH1 9294
AP1S1 9286
H2BC21 9283
IL10 9272
CYFIP1 9265
ARPC1B 9259
ST6GALNAC3 9134
GPR84 9133
GUCY2C 9122
MAPK14 9104

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
WASF1 9520.0
HRH2 9466.0
CD163 9462.0
PRKACA 9429.0
GGT1 9426.0
ADM 9378.0
GNG10 9349.0
GPR27 9340.0
FCGR1A 9323.0
GRB2 9304.0
IMPDH1 9294.0
AP1S1 9286.0
H2BC21 9283.0
IL10 9272.0
CYFIP1 9265.0
ARPC1B 9259.0
ST6GALNAC3 9134.0
GPR84 9133.0
GUCY2C 9122.0
MAPK14 9104.0
TLR2 9103.0
SYK 9076.0
FURIN 9075.0
ARF1 9064.0
MAP2K1 9063.0
FKBP1A 9056.0
H2BC12 9051.0
ACTB 9011.0
CLTC 9000.0
ADCY3 8984.0
HCK 8976.0
MAPK3 8953.0
MYO10 8918.0
IL1R1 8917.0
CRK 8906.0
NLRP3 8901.0
ARPC1A 8894.0
ENO1 8890.0
MAP2K6 8887.0
CHMP4B 8866.0
FCGR2A 8845.0
NUP58 8820.0
CEBPD 8816.0
GNG5 8815.0
RAC1 8793.0
CHMP2A 8780.0
MAP2K3 8748.0
RAB7A 8742.0
AP1B1 8730.0
RB1 8707.0
UBAP1 8701.0
ARPC5 8686.0
PGK1 8672.0
ST3GAL2 8669.0
PYCARD 8638.0
AP2M1 8627.0
PRKAR1A 8607.0
MEFV 8605.0
ACTG1 8562.0
WAS 8560.0
PSMB7 8485.0
FGR 8478.0
ADORA2B 8437.0
DNAJC3 8435.0
PSMD4 8402.0
CLTA 8376.0
WASF2 8369.0
ENTPD1 8360.0
CHMP3 8349.0
GNB1 8294.0
TXN 8285.0
ARPC3 8277.0
COMT 8273.0
PSME3 8251.0
JAK3 8219.0
TXNRD1 8192.0
PAK2 8185.0
TRIM27 8142.0
GNB2 8141.0
IL6R 8132.0
ADAM17 8110.0
PSMB5 8101.0
GNAI2 8075.0
HSPA1A 8071.0
ATP6V1H 8064.0
MAP1LC3B 8043.0
AP2S1 8026.0
C3AR1 8012.0
VPS37C 8010.0
H2BC5 8003.0
NCOR2 7985.0
TAF12 7977.0
GNAI3 7953.0
H2AC6 7934.0
NUP214 7921.0
PRKAR1B 7918.0
H2BC11 7912.0
GNAS 7909.0
VAV1 7896.0
TBL1X 7887.0
NEDD4L 7875.0
ACTR2 7870.0
PSMD6 7846.0
PSTPIP1 7841.0
ACTR3 7818.0
LYN 7809.0
TSG101 7786.0
GSK3A 7760.0
DYNC1I2 7735.0
DOCK2 7725.0
NCKAP1L 7673.0
VPS25 7638.0
P2RX4 7630.0
SH3GL1 7625.0
PSMD9 7620.0
POLR2E 7563.0
H2BC18 7547.0
CDC42 7537.0
HNRNPK 7522.0
ELOC 7519.0
ARPC4 7516.0
H2AC11 7513.0
MAPK1 7493.0
ROCK1 7489.0
ELOB 7482.0
CBL 7480.0
VEGFA 7467.0
NCKAP1 7462.0
PSMD2 7411.0
MVB12A 7400.0
ARPC2 7390.0
H2BC4 7389.0
IL18 7381.0
GNB4 7336.0
ANTXR2 7331.0
PSMA1 7329.0
DOCK1 7314.0
ELOA 7312.0
H2BC17 7285.0
AP2A2 7257.0
PSMD1 7241.0
TAF13 7217.0
BTK 7206.0
RXFP2 7189.0
RPL26L1 7176.0
PSMB3 7171.0
IL1RAP 7150.0
TAF10 7110.0
RAB5A 7103.0
PSMA7 7096.0
TYK2 7087.0
ABI1 7082.0
GTF2A2 7066.0
BRK1 7032.0
PSMC1 7021.0
DYNC1LI1 6941.0
CYBA 6922.0
SUMO1 6889.0
VCP 6886.0
MAP2K4 6866.0
AP2A1 6832.0
PSMB6 6813.0
WASF3 6808.0
MAP2K2 6794.0
XRCC4 6758.0
ST6GALNAC2 6746.0
PRKAR2B 6741.0
AP1M1 6711.0
H3C15 6699.5
MYO5A 6693.0
MYH9 6685.0
POLR2J 6671.0
PSMF1 6659.0
UBB 6639.0
PSMC6 6635.0
GSK3B 6634.0
INSL3 6594.0
PSMD12 6556.0
PDCD6IP 6528.0
BECN1 6516.0
GALNT1 6508.0
GNG11 6495.0
VPS37A 6467.0
AHCYL1 6456.0
MYO9B 6424.0
CTNNB1 6408.0
CALR 6340.0
LTF 6306.0
NFKB1 6277.0
SLC25A6 6264.0
ELMO1 6258.0
MGAT1 6257.0
PSMD11 6231.0
VTA1 6185.0
CTDP1 6180.0
SH3KBP1 6173.0
PRKAR2A 6166.0
STAM2 6159.0
ROCK2 6138.0
RLN3 6033.0
SNF8 5973.0
PSMA6 5970.0
PSMD7 5963.0
DYNLL1 5952.0
PSMD13 5948.0
CD9 5940.0
BRD4 5892.0
NCOR1 5887.0
ADM2 5881.0
ITPR2 5842.0
ST3GAL4 5781.0
GTF2E2 5767.0
PSMD8 5757.0
CHMP1A 5756.0
SEC13 5748.0
CHMP2B 5714.0
WIPF2 5713.0
DVL3 5656.0
CANX 5528.0
CHMP6 5499.0
HDAC2 5482.0
GTF2F2 5434.0
RPS9 5421.0
H2BC9 5394.0
XRCC5 5384.0
PSMA2 5339.0
LIG4 5316.0
H2BC15 5312.0
POLR2L 5305.0
ADCY4 5270.0
CALCRL 5232.0
PRKCSH 5220.0
VPS4B 5212.0
CDK7 5211.0
CORO1A 5178.0
MVB12B 5175.0
GRSF1 5169.0
RAE1 5164.0
TGFB1 5153.0
CTSG 5115.0
SYT1 5056.0
HBEGF 5013.0
ELL 5009.0
PLCG2 5006.0
H2AC20 4972.0
KPNA4 4957.0
GTF2F1 4951.0
CHMP5 4943.0
VAV3 4894.0
IL1B 4807.0
CBX1 4751.0
HDAC3 4673.0
PSMD3 4618.0
POLR2F 4604.0
TBL1XR1 4556.0
NUP50 4521.0
HGS 4513.0
RPL3L 4503.0
PTK2 4462.0
UBC 4439.0
ELMO2 4397.0
PARP4 4362.0
SEM1 4348.0
NMT1 4328.0
GNG8 4296.0
SKP1 4287.0
DYNC1LI2 4273.0
CTSL 4231.0
CASP1 4224.0
VPS28 4199.0
RHBDF2 4197.0
DYNC1I1 4187.0
EPS15 4138.0
PSMB2 4084.0
PDZD3 4005.0
AP1G1 3987.0
RBX1 3934.0
VPS37B 3908.0
GTF2H5 3874.0
NELFE 3860.0
JUN 3722.0
VHL 3674.0
ERCC2 3547.0
GTF2B 3515.0
POLR2G 3508.0
P2RX7 3475.0
PSMD5 3426.0
PSMB1 3374.0
GNAI1 3329.0
MYO1C 3310.0
ADORA2A 3293.0
TBK1 3229.0
MRC1 3109.0
NUP98 3101.0
RNGTT 3088.0
NUP37 3074.0
GTF2H2 2984.0
GNAZ 2909.0
SUPT4H1 2890.0
CCNK 2877.0
POMC 2855.0
RAMP3 2854.0
ATP1A1 2813.0
GTF2A1 2713.0
JAK2 2691.0
PSMD14 2611.0
PSMC2 2598.0
PSMB4 2523.0
KPNB1 2430.0
CHMP4A 2400.0
GTF2E1 2287.0
SFPQ 2253.0
TAF7 2139.0
RPS27L 2061.0
TSHR 2051.0
PSMC3 1976.0
AP1M2 1832.0
RCC1 1766.0
IRS1 1741.0
MAP2K7 1654.0
PIK3C3 1619.0
POLR2C 1616.0
PSMD10 1559.0
SUGT1 1544.0
PTGER2 1463.0
HSP90AA1 1326.0
KPNA1 1296.0
STAM 1285.0
TAF9 1250.0
UBA52 1121.0
ELK1 1040.0
KPNA3 923.0
GNG3 890.0
CUL5 834.0
SLC25A5 826.0
VPS4A 784.0
CCNH 774.0
NUP62 769.0
WIPF1 569.0
GNB5 512.0
NR3C1 511.0
ST3GAL3 505.0
ZCRB1 487.0
SYT2 461.0
RPS4Y1 424.0
POLR2I 396.0
NELFB 374.0
IGHV1-2 360.0
NCKIPSD 328.0
EEF2 306.0
WASL 299.0
AVPR2 291.0
IGHV2-5 230.0
ABL1 226.0
ADCY9 123.0
HMGA1 117.0
IGHV3-53 103.0
RPL36AL 32.0
RPLP1 19.0
DVL1 0.0
CXCR4 -45.0
ITGB1 -94.0
BAIAP2 -215.0
RPS24 -263.0
FAU -362.0
IGHV3-7 -441.0
PABPN1 -526.0
PSMA4 -616.0
IGHV1-46 -618.0
TLR7 -625.0
ST6GALNAC4 -629.0
IGHV3-48 -668.0
GGT5 -695.0
GPR83 -743.0
UBE2I -764.0
IGKV3-11 -781.0
RANBP2 -820.0
PSMC5 -863.0
GPS2 -889.0
TCEA1 -943.0
RPL15 -963.0
GANAB -986.0
IGKV1-39 -989.0
RPLP0 -1000.0
IGLV7-46 -1016.0
NFKB2 -1165.0
IGKV1-5 -1184.0
XPO1 -1185.0
RPL8 -1187.0
IGLV2-8 -1294.0
IGKV5-2 -1298.0
IGHV3-23 -1317.0
CREB1 -1378.0
RPS26 -1430.0
IGHV3-13 -1443.0
RPL28 -1462.0
IGLV2-18 -1524.0
IGKV1-16 -1528.0
IGLV4-69 -1559.0
IGKV1D-39 -1574.0
ADCY6 -1608.0
RPL22L1 -1619.0
TAF4 -1698.0
RPS13 -1749.0
POLR2K -1783.0
RELA -1803.0
IGHV1-69 -1822.0
TAF3 -1850.0
SV2B -1857.0
RBBP4 -1870.0
RPL9 -1872.0
IGLV10-54 -1884.0
RPL7 -1955.0
IGLV1-36 -2030.0
IGKV2-30 -2045.0
CALM1 -2081.0
RPS8 -2083.0
IGLV7-43 -2089.0
VPS33B -2091.0
IGLV3-19 -2111.0
IGHV3-11 -2134.0
GNG4 -2154.0
GTF2H3 -2235.0
AP1S2 -2261.0
IGKV3-15 -2297.0
GNB3 -2397.0
SUZ12 -2409.0
IGKV1-33 -2424.0
HTR7 -2438.0
IGHV3-30 -2484.0
POLR2B -2523.0
IGKV4-1 -2532.0
HLA-A -2573.0
TAF9B -2599.0
DPEP2 -2705.0
AP2B1 -2709.0
PLK2 -2748.0
RPL27 -2855.0
IGKV1-17 -2871.0
IGLV2-23 -2878.0
IGLV6-57 -2885.0
IGHV4-59 -2892.0
DPEP3 -2894.0
ADCY2 -2896.0
IGLV2-11 -2905.0
GTF2H1 -2913.0
GTF2H4 -2916.0
TAF11 -2938.0
POLR2H -2942.0
STX1B -2952.0
SV2C -2979.0
IGHV3-33 -2988.0
RPL39 -3006.0
IGHV4-34 -3016.0
NUP85 -3049.0
MOGS -3051.0
PSMB8 -3076.0
IGKV3-20 -3085.0
POLR2A -3092.0
IGHV2-70 -3138.0
IGLV1-44 -3258.0
ADCY7 -3286.0
RPL23 -3314.0
RPL6 -3354.0
RPL13 -3431.0
IGHG3 -3481.0
RPL4 -3582.0
RPL29 -3611.0
RPL7A -3665.0
RPS15 -3673.0
NELFA -3886.0
IGKV3D-20 -3894.0
CDK9 -3927.0
RPL37A -3946.0
DYNLL2 -3980.0
POLR2D -4024.0
STX1A -4052.0
VAV2 -4055.0
PIK3R4 -4062.0
RPS21 -4079.0
IGLV3-1 -4159.0
PARP9 -4400.0
HTR6 -4426.0
IGKC -4428.0
XRCC6 -4471.0
RPS2 -4499.0
TAF5 -4514.0
RPL31 -4541.0
IGHV4-39 -4582.0
RPS16 -4669.0
RPS3A -4694.0
RPS28 -4713.0
RPL5 -4728.0
IGLV3-21 -4735.0
RPL22 -4740.0
BANF1 -4752.0
IGLV1-40 -4788.0
BTRC -4924.0
IGLV3-25 -4933.0
IGLV1-51 -4956.0
PARP6 -4959.0
RPS7 -4968.0
TRIM28 -5056.0
RPL18 -5080.0
CRHR2 -5119.0
GNG7 -5198.0
CCNT2 -5205.0
IGLC7 -5281.0
PSMA3 -5285.0
RPL36 -5287.0
CD4 -5406.0
IGLV8-61 -5427.0
RPL17 -5431.0
IGKV1-12 -5446.0
RPS14 -5463.0
NOXA1 -5464.0
IGLC3 -5477.0
IGLC2 -5510.0
AP1S3 -5522.0
NUP42 -5564.0
IGKV2D-28 -5634.0
RPS5 -5691.0
PSMB10 -5735.0
RPS15A -5742.0
RPS10 -5793.0
RPL24 -5799.0
IGKV2-28 -5808.0
RPL38 -5840.0
NCBP1 -5853.0
IGLV5-45 -5869.0
IGLV3-27 -5874.0
RPS3 -5914.0
TAF2 -5945.0
NT5E -5964.0
RPS12 -5987.0
TLR9 -5999.0
RPL35A -6015.0
IGLV1-47 -6018.0
DUT -6046.0
PSMA5 -6053.0
SEH1L -6069.0
RPL18A -6070.0
PSME4 -6087.0
VIPR1 -6156.0
IGLC1 -6157.0
RPS6 -6160.0
ENTPD5 -6179.0
CRBN -6190.0
IGHG1 -6201.0
RPS17 -6247.0
RPL27A -6257.0
RPL11 -6261.0
NELFCD -6277.0
RPL19 -6281.0
RPS4X -6285.0
RPS23 -6292.0
NUP153 -6321.0
RPSA -6323.0
RPS25 -6365.0
RPL37 -6375.0
TAF15 -6454.0
RPL21 -6458.0
FZD7 -6508.0
RPL10 -6534.0
H2BU1 -6555.0
RPL26 -6612.0
GPR15 -6636.0
DUSP16 -6655.0
RPL10A -6686.0
RPL32 -6709.0
RPL14 -6710.0
SUPT5H -6716.0
PPIA -6766.0
RAN -6791.0
PDCD1 -6792.0
RPL34 -6802.0
VPS36 -6848.0
HSP90AB1 -6863.0
RPL41 -6866.0
KPNA2 -6910.0
IGHG4 -6911.0
B2M -6920.0
RPS27A -6938.0
TUBB -6956.0
RPS19 -6965.0
RPL30 -7020.0
TPR -7028.0
RPL12 -7053.0
RPLP2 -7087.0
GPBAR1 -7132.0
POM121C -7188.0
RPS11 -7243.0
IGHG2 -7250.0
TAF6 -7352.0
IGLV3-12 -7358.0
RPL36A -7376.0
ST3GAL1 -7442.0
PSMA8 -7606.0
ITPR1 -7629.0
ADRB1 -7674.0
CYSLTR1 -7675.0
DYNC1H1 -7685.0
SIGMAR1 -7732.0
RPS18 -7744.0
NUP133 -7762.0
ERCC3 -7783.0
GNG2 -7795.0
RPS29 -7940.0
RAMP1 -8039.0
TAF4B -8069.0
RPL35 -8092.0
CD8B -8188.0
RPL13A -8212.0
ADCY5 -8235.0
POM121 -8299.0
IGLV2-14 -8345.0
AAAS -8389.0
PARP10 -8400.0
CTNND1 -8403.0
PARP8 -8409.0
TAF1 -8476.0
NUP54 -8479.0
PACS1 -8486.0
RPL3 -8561.0
CBLL1 -8620.0
VAMP1 -8625.0
RLN2 -8636.0
MNAT1 -8687.0
PML -8693.0
CHMP7 -8802.0
RPL39L -8805.0
SRC -8820.0
CCR5 -8861.0
RPS20 -8886.0
CYSLTR2 -8970.0
UVRAG -9024.0
EIF2AK2 -9116.0
PTGIR -9126.0
PSMC4 -9127.0
TBP -9167.0
S1PR1 -9211.0
EED -9348.0
CPSF4 -9416.0
MAPK8 -9428.0
CCNT1 -9469.0
NUP43 -9517.0
NPM1 -9532.0
NCBP2 -9558.0
RPL23A -9567.0
TXNIP -9600.0
RANBP1 -9657.0
EZH2 -9741.0
PSIP1 -9743.0
RPS27 -9756.0
DDX5 -9843.0
IMPDH2 -9916.0
GPR150 -9942.0
PSME1 -9991.0
CD28 -10202.0
NUP155 -10233.0
ITPR3 -10308.0
PSME2 -10336.0
CYFIP2 -10367.0
NUP107 -10421.0
PRKX -10428.0
NUP160 -10557.0
DAXX -10575.0
IPO5 -10591.0
FEN1 -10593.0
NUP35 -10611.0
GPR25 -10677.0
NUP210 -10726.0
SV2A -10890.0
P2RY11 -10907.0
ABI2 -10915.0
JAK1 -10955.0
ITGA4 -11043.0
LIG1 -11053.0
RIPK1 -11074.0
RNMT -11086.0
PLCG1 -11120.0
DVL2 -11152.0
SSRP1 -11162.0
MC1R -11184.0
NUP205 -11321.0
PSMB9 -11324.0
SUPT16H -11359.0
NUP88 -11397.0
H2AW -11403.0
DBP -11441.0
NCK1 -11454.0
CDH1 -11500.0
CD3G -11526.0
NUP93 -11620.0
NUP188 -11624.0
FYN -11675.0
GPR20 -11696.0
PTGER4 -11697.0
RANGAP1 -11722.0
PARP1 -11764.0
VAMP2 -11779.0
PARP16 -11830.0
LCK -11838.0
SLC25A4 -11858.0
PARP14 -11869.0
SCT -11886.0
ADRB2 -11892.0
KPNA5 -11893.0
RNF213 -11905.0
PRKACB -11959.0
APOBEC3G -11967.0
FCGR3A -12005.0
PTGDR -12021.0
ISG15 -12032.0
NMT2 -12035.0
ST6GAL1 -12052.0
GNGT2 -12086.0
GIPR -12100.0
YES1 -12142.0
VIPR2 -12153.0
RBBP7 -12155.0
NDC1 -12173.0
C3 -12262.0
CD247 -12345.0


trans-Golgi Network Vesicle Budding

trans-Golgi Network Vesicle Budding
1363
set trans-Golgi Network Vesicle Budding
setSize 69
pANOVA 9.29e-08
s.dist 0.372
p.adjustANOVA 1.6e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
VAMP7 9499
GNS 9360
AP1S1 9286
APP 9177
SORT1 9171
ARF1 9064
PICALM 9022
CLTC 9000
CTSZ 8975
CPD 8824
CHMP2A 8780
AP1B1 8730
TGOLN2 8714
FTL 8665
RAB5C 8655
BLOC1S1 8630
SNAP23 8628
CLTA 8376
AP3B1 8365
AP3S1 7874

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
VAMP7 9499
GNS 9360
AP1S1 9286
APP 9177
SORT1 9171
ARF1 9064
PICALM 9022
CLTC 9000
CTSZ 8975
CPD 8824
CHMP2A 8780
AP1B1 8730
TGOLN2 8714
FTL 8665
RAB5C 8655
BLOC1S1 8630
SNAP23 8628
CLTA 8376
AP3B1 8365
AP3S1 7874
SNX2 7861
SNAPIN 7443
IGF2R 7149
BLOC1S6 6815
DNASE2 6745
AP1M1 6711
OCRL 6442
AP4E1 6419
DNM2 6089
CLTB 6084
YIPF6 5857
ACBD3 5816
VAMP8 5218
FTH1 4902
DNAJC6 4640
HGS 4513
AP1G1 3987
CLINT1 3815
PUM1 3250
GAK 2570
NECAP1 2220
ARRB1 1998
AP1M2 1832
TFRC 1524
NAPA 1432
TBC1D8B 1417
DTNBP1 1014
STX4 606
TXNDC5 393
AP4M1 138
SNX9 -430
AP1S2 -2261
SNX5 -3305
TPD52L1 -3542
SH3D19 -4011
GBF1 -4290
PIK3C2A -5194
GOLGB1 -5370
AP1S3 -5522
AP1G2 -5590
AP4S1 -5731
AP4B1 -7235
BLOC1S4 -7493
M6PR -8519
BLOC1S3 -8703
TPD52 -9644
HIP1R -10615
HSPA8 -10922
VAMP2 -11779


ESR-mediated signaling

ESR-mediated signaling
333
set ESR-mediated signaling
setSize 161
pANOVA 1.07e-07
s.dist 0.243
p.adjustANOVA 1.83e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
CTSD 9433
H2AJ 9374
GNG10 9349
H2BC21 9283
FKBP5 9091
AGO4 9070
H2BC12 9051
CARM1 9020
MAPK3 8953
TGFA 8889
GNG5 8815
FOXO3 8682
H3-3A 8661
ZDHHC7 8636
TLE3 8558
GNB1 8294
SP1 8193
EGF 8179
GNB2 8141
GNAI2 8075

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CTSD 9433.0
H2AJ 9374.0
GNG10 9349.0
H2BC21 9283.0
FKBP5 9091.0
AGO4 9070.0
H2BC12 9051.0
CARM1 9020.0
MAPK3 8953.0
TGFA 8889.0
GNG5 8815.0
FOXO3 8682.0
H3-3A 8661.0
ZDHHC7 8636.0
TLE3 8558.0
GNB1 8294.0
SP1 8193.0
EGF 8179.0
GNB2 8141.0
GNAI2 8075.0
H2BC5 8003.0
GNAI3 7953.0
H2AC6 7934.0
H2BC11 7912.0
KDM4B 7911.0
SPHK1 7657.0
TFF3 7621.0
POLR2E 7563.0
RUNX1 7529.0
MAPK1 7493.0
H2BC4 7389.0
GNB4 7336.0
H2BC17 7285.0
SRF 7079.0
GTF2A2 7066.0
H3C15 6699.5
POLR2J 6671.0
GNG11 6495.0
USF2 6440.0
PDPK1 6136.0
EP300 6129.0
H2AZ1 6036.0
IGF1R 5990.0
AREG 5977.0
AGO1 5654.0
FOS 5460.0
GTF2F2 5434.0
H2BC9 5394.0
NRAS 5363.0
S1PR3 5323.0
H2BC15 5312.0
POLR2L 5305.0
STAG2 5301.0
HBEGF 5013.0
PIK3R2 5010.0
H2AC20 4972.0
GTF2F1 4951.0
USF1 4829.0
PPID 4695.0
PIK3CA 4629.0
NRIP1 4609.0
POLR2F 4604.0
CAV2 4516.0
NCOA1 4483.0
PTK2 4462.0
KCTD6 4371.0
GNG8 4296.0
SHC1 4161.0
PTGES3 4125.0
MMP7 3918.0
JUN 3722.0
KRAS 3702.0
STRN 3695.0
AKT1 3614.0
NCOA3 3522.0
POLR2G 3508.0
CREBBP 3423.0
GNAI1 3329.0
ZNF217 3232.0
AGO2 2995.0
GTF2A1 2713.0
EPGN 2662.0
MYC 2304.0
ATF2 2085.0
CBFB 2078.0
CAV1 1969.0
EREG 1888.0
RAD21 1709.0
MMP9 1690.0
POLR2C 1616.0
JUND 1549.0
POU2F1 1537.0
FOSB 1368.0
HSP90AA1 1326.0
KAT5 1314.0
NCOA2 1092.0
ELK1 1040.0
GNG3 890.0
FKBP4 832.0
SMC1A 613.0
HDAC1 587.0
YY1 537.0
GNB5 512.0
AKT2 433.0
POLR2I 396.0
MYB 302.0
CHD1 69.0
AGO3 -1011.0
XPO1 -1185.0
H2AZ2 -1209.0
CREB1 -1378.0
POLR2K -1783.0
SMC3 -1975.0
NOS3 -2059.0
CALM1 -2081.0
GNG4 -2154.0
GNB3 -2397.0
KAT2B -2414.0
POLR2B -2523.0
POLR2H -2942.0
POLR2A -3092.0
HRAS -3382.0
UHMK1 -3877.0
CDK9 -3927.0
KANK1 -3964.0
POLR2D -4024.0
MED1 -4036.0
TNRC6B -4518.0
BCL2 -4704.0
GNG7 -5198.0
TNRC6A -5613.0
STAG1 -6347.0
ZDHHC21 -6453.0
H2BU1 -6555.0
HSP90AB1 -6863.0
KPNA2 -6910.0
GREB1 -6937.0
CCND1 -6970.0
CXXC5 -7037.0
PPP5C -7462.0
GNG2 -7795.0
CDKN1B -8207.0
SRC -8820.0
ESR1 -9122.0
TBP -9167.0
PRMT1 -9229.0
ESR2 -9250.0
KDM1A -9430.0
CCNT1 -9469.0
PIK3R1 -9505.0
DDX5 -9843.0
EBAG9 -10187.0
GPAM -10241.0
AXIN1 -10285.0
PRKCZ -11629.0
TNRC6C -11828.0
AKT3 -11849.0
MOV10 -11991.0
PIK3R3 -12015.0
GNGT2 -12086.0
GATA3 -12191.0


PD-1 signaling

PD-1 signaling
779
set PD-1 signaling
setSize 28
pANOVA 1.11e-07
s.dist -0.579
p.adjustANOVA 1.87e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
CD247 -12345
HLA-DPA1 -12316
HLA-DPB1 -12248
HLA-DRA -12009
TRBC1 -12006
HLA-DQA1 -11992
LCK -11838
CD3G -11526
TRAC -11482
CD3D -11401
CD3E -11302
TRBV12-3 -10436
TRAV19 -9915
TRAV29DV5 -9673
TRBV7-9 -9539
HLA-DQB2 -9401
HLA-DRB1 -8075
CD274 -7563
TRAV8-4 -7261
PDCD1 -6792

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CD247 -12345
HLA-DPA1 -12316
HLA-DPB1 -12248
HLA-DRA -12009
TRBC1 -12006
HLA-DQA1 -11992
LCK -11838
CD3G -11526
TRAC -11482
CD3D -11401
CD3E -11302
TRBV12-3 -10436
TRAV19 -9915
TRAV29DV5 -9673
TRBV7-9 -9539
HLA-DQB2 -9401
HLA-DRB1 -8075
CD274 -7563
TRAV8-4 -7261
PDCD1 -6792
HLA-DQB1 -6416
CD4 -5406
HLA-DRB5 -4971
HLA-DQA2 -4806
PDCD1LG2 -3326
CSK 5219
PTPN11 5314
PTPN6 6096


rRNA modification in the nucleus and cytosol

rRNA modification in the nucleus and cytosol
1353
set rRNA modification in the nucleus and cytosol
setSize 59
pANOVA 1.39e-07
s.dist -0.396
p.adjustANOVA 2.32e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
NAT10 -11952
NOP56 -11750
BMS1 -11670
DKC1 -11637
PDCD11 -11518
UTP4 -11494
DDX47 -11299
IMP4 -10976
WDR46 -10970
NOL6 -10908
NOP14 -10866
UTP15 -10603
UTP20 -10529
NOL11 -10471
HEATR1 -10345
EMG1 -10189
FBL -10188
RRP9 -10080
NOP2 -9952
NOP58 -9951

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NAT10 -11952
NOP56 -11750
BMS1 -11670
DKC1 -11637
PDCD11 -11518
UTP4 -11494
DDX47 -11299
IMP4 -10976
WDR46 -10970
NOL6 -10908
NOP14 -10866
UTP15 -10603
UTP20 -10529
NOL11 -10471
HEATR1 -10345
EMG1 -10189
FBL -10188
RRP9 -10080
NOP2 -9952
NOP58 -9951
WDR75 -9921
THUMPD1 -9802
IMP3 -9459
KRR1 -8623
DHX37 -8267
DIMT1 -7988
MPHOSPH10 -7790
WDR43 -7687
GAR1 -6941
SNU13 -6871
PNO1 -6861
WDR3 -6619
RPS6 -6160
DCAF13 -5572
NOC4L -5483
RPS14 -5463
RPS7 -4968
UTP6 -4507
RPS2 -4499
WDR36 -3945
NHP2 -3471
TBL3 -3437
UTP3 -2903
RRP7A -2806
SNORD3A -2539
UTP14C -2073
UTP14A -1821
RRP36 -1672
PWP2 -1207
RCL1 -757
DDX52 454
TRMT112 738
TSR3 3846
FCF1 4472
UTP11 4631
DDX49 4872
UTP18 5114
RPS9 5421
NOP10 8332


RAB GEFs exchange GTP for GDP on RABs

RAB GEFs exchange GTP for GDP on RABs
878
set RAB GEFs exchange GTP for GDP on RABs
setSize 88
pANOVA 1.51e-07
s.dist 0.324
p.adjustANOVA 2.48e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
RAB32 9463
RAB13 9440
RAB31 9356
SBF2 9078
RAB1A 9052
YWHAE 9045
RAB3IL1 9005
RAB10 8926
RAB7A 8742
RAB5C 8655
RAB27A 8411
RIN2 8355
RAB1B 8313
RAB6A 8148
RAB3A 8133
DENND3 7938
TRAPPC1 7806
RAB18 7801
DENND5A 7736
RIN1 7602

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RAB32 9463
RAB13 9440
RAB31 9356
SBF2 9078
RAB1A 9052
YWHAE 9045
RAB3IL1 9005
RAB10 8926
RAB7A 8742
RAB5C 8655
RAB27A 8411
RIN2 8355
RAB1B 8313
RAB6A 8148
RAB3A 8133
DENND3 7938
TRAPPC1 7806
RAB18 7801
DENND5A 7736
RIN1 7602
RABGEF1 7466
DENND1A 7441
GDI2 7282
ULK1 7125
TRAPPC3 7114
RAB39A 7113
RAB5A 7103
RAB14 7095
RIC1 6824
GAPVD1 6799
TRAPPC8 6735
RAB5B 6690
MON1B 6612
RAB8B 6529
TRAPPC12 6310
RAB21 6165
RAB6B 6053
DENND2C 5898
RAB3GAP1 5768
GDI1 5739
HPS1 5605
TRAPPC9 5333
TRAPPC11 5319
TRAPPC5 5191
RGP1 4538
RAB3GAP2 4429
CCZ1 4242
TRAPPC6B 4147
RAB9A 4088
RAB35 3981
RAB8A 3880
AKT1 3614
RAB27B 3386
RAB3IP 3237
ALS2 3176
DENND4B 3139
DENND6B 2993
CHM 2273
CCZ1B 990
AKT2 433
ANKRD27 186
DENND6A -562
RAB12 -856
CHML -1515
RAB7B -1531
TRAPPC2L -2299
TRAPPC13 -2479
MON1A -2910
DENND5B -4249
DENND4A -5540
RAB9B -6552
TRAPPC4 -6712
DENND1C -7377
DENND4C -7574
ALS2CL -8315
DENND2A -8355
TRAPPC2 -8704
RAB38 -8714
DENND1B -9284
TRAPPC10 -9369
RINL -10326
SBF1 -10530
TRAPPC6A -10917
RAB39B -11529
HPS4 -11558
AKT3 -11849
MADD -11899
DENND2D -12293


Rab regulation of trafficking

Rab regulation of trafficking
933
set Rab regulation of trafficking
setSize 121
pANOVA 1.59e-07
s.dist 0.276
p.adjustANOVA 2.59e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
RAB32 9463
RAB13 9440
RAB31 9356
TBC1D2 9301
SBF2 9078
RAB1A 9052
YWHAE 9045
GABARAPL2 9044
RAB3IL1 9005
RAB10 8926
TBC1D14 8897
RAB7A 8742
RAB11A 8688
RAB5C 8655
RAB27A 8411
RIN2 8355
RAB1B 8313
RAB6A 8148
RAB3A 8133
TBC1D10B 8078

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RAB32 9463
RAB13 9440
RAB31 9356
TBC1D2 9301
SBF2 9078
RAB1A 9052
YWHAE 9045
GABARAPL2 9044
RAB3IL1 9005
RAB10 8926
TBC1D14 8897
RAB7A 8742
RAB11A 8688
RAB5C 8655
RAB27A 8411
RIN2 8355
RAB1B 8313
RAB6A 8148
RAB3A 8133
TBC1D10B 8078
MAP1LC3B 8043
RAB4A 7941
DENND3 7938
GABARAP 7904
TRAPPC1 7806
RAB18 7801
DENND5A 7736
RIN1 7602
RABGEF1 7466
DENND1A 7441
GDI2 7282
RAB33B 7267
ULK1 7125
TRAPPC3 7114
RAB39A 7113
RAB5A 7103
RAB14 7095
RIC1 6824
GAPVD1 6799
TRAPPC8 6735
RAB5B 6690
MON1B 6612
RAB8B 6529
TBC1D7 6452
TRAPPC12 6310
RAB21 6165
RAB6B 6053
DENND2C 5898
RAB3GAP1 5768
GDI1 5739
HPS1 5605
TRAPPC9 5333
TRAPPC11 5319
TRAPPC5 5191
RGP1 4538
RAB3GAP2 4429
RAB11B 4402
CCZ1 4242
TRAPPC6B 4147
RAB9A 4088
RAB35 3981
RAB8A 3880
GGA3 3816
TBC1D13 3782
TBC1D15 3665
AKT1 3614
TBC1D16 3409
RAB27B 3386
RAB3IP 3237
TBC1D24 3200
ALS2 3176
DENND4B 3139
DENND6B 2993
GGA1 2310
CHM 2273
RABGAP1 2052
ARF6 1377
CCZ1B 990
AKT2 433
ANKRD27 186
TBC1D20 -18
TBC1D3 -66
DENND6A -562
TSC2 -804
RAB12 -856
CHML -1515
RAB7B -1531
TSC1 -2118
TRAPPC2L -2299
TRAPPC13 -2479
MON1A -2910
DENND5B -4249
DENND4A -5540
RAB9B -6552
GGA2 -6587
TRAPPC4 -6712
TBC1D25 -7372
DENND1C -7377
DENND4C -7574
ALS2CL -8315
DENND2A -8355
TRAPPC2 -8704
RAB38 -8714
TBC1D17 -8716
DENND1B -9284
TRAPPC10 -9369
POLG -9889
SYTL1 -10104
RINL -10326
SBF1 -10530
TRAPPC6A -10917
RAB33A -10940
RAB39B -11529
HPS4 -11558
RABEP1 -11754
OPTN -11766
AKT3 -11849
TBC1D10C -11861
MADD -11899
TBC1D10A -12025
DENND2D -12293


MAP2K and MAPK activation

MAP2K and MAPK activation
611
set MAP2K and MAPK activation
setSize 34
pANOVA 1.81e-07
s.dist 0.517
p.adjustANOVA 2.91e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
MAP2K1 9063
MAPK3 8953
ITGA2B 8893
APBB1IP 8744
MARK3 8697
TLN1 8525
ARRB2 8490
ITGB3 8291
FN1 8284
IQGAP1 8152
RAF1 7879
LAMTOR3 7574
LAMTOR2 7567
MAPK1 7493
VCL 7328
RAP1A 7305
MAP2K2 6794
VWF 6641
YWHAB 6385
NRAS 5363

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MAP2K1 9063
MAPK3 8953
ITGA2B 8893
APBB1IP 8744
MARK3 8697
TLN1 8525
ARRB2 8490
ITGB3 8291
FN1 8284
IQGAP1 8152
RAF1 7879
LAMTOR3 7574
LAMTOR2 7567
MAPK1 7493
VCL 7328
RAP1A 7305
MAP2K2 6794
VWF 6641
YWHAB 6385
NRAS 5363
CSK 5219
KSR1 4167
WDR83 3718
KRAS 3702
RAP1B 3206
ARAF 2644
ARRB1 1998
BRAF 1308
KSR2 -3361
HRAS -3382
CNKSR2 -4781
CNKSR1 -7089
SRC -8820
PEBP1 -11270


tRNA processing

tRNA processing
1360
set tRNA processing
setSize 136
pANOVA 2.88e-07
s.dist -0.255
p.adjustANOVA 4.57e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
MT-TP -12349
TSEN54 -12272
NDC1 -12173
TP53RK -12040
THADA -11763
ELAC2 -11761
NUP188 -11624
NUP93 -11620
ALKBH8 -11614
NUP88 -11397
NUP205 -11321
TRMT11 -11243
TSEN2 -10933
NUP210 -10726
LCMT2 -10707
NUP35 -10611
NUP160 -10557
THG1L -10487
NUP107 -10421
NUP155 -10233

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MT-TP -12349
TSEN54 -12272
NDC1 -12173
TP53RK -12040
THADA -11763
ELAC2 -11761
NUP188 -11624
NUP93 -11620
ALKBH8 -11614
NUP88 -11397
NUP205 -11321
TRMT11 -11243
TSEN2 -10933
NUP210 -10726
LCMT2 -10707
NUP35 -10611
NUP160 -10557
THG1L -10487
NUP107 -10421
NUP155 -10233
WDR4 -10005
TRMT13 -9983
ADAT2 -9944
TSEN15 -9901
POP5 -9676
QTRT1 -9595
TRMT61A -9554
NUP43 -9517
CPSF4 -9416
TRMU -9261
TYW1 -9203
ADAT1 -9178
CDKAL1 -9175
CTU2 -8961
FTSJ1 -8550
NUP54 -8479
AAAS -8389
MTO1 -8384
TYW3 -8331
POM121 -8299
RPP25 -8247
FAM98B -8222
RPP30 -8101
TRMT61B -7979
NUP133 -7762
NSUN6 -7729
TRNT1 -7551
GTPBP3 -7252
POM121C -7188
MT-TL2 -7170
METTL1 -7148
RPP38 -7076
TPR -7028
TRMT44 -6885
OSGEP -6794
RAN -6791
MT-TE -6588
MT-ND2 -6560
CSTF2 -6444
PUS1 -6392
NUP153 -6321
SEH1L -6069
C2orf49 -5807
NUP42 -5564
PUS7 -5462
MT-TY -5442
RPP21 -5355
TPRKB -5218
RPP40 -4835
MT-TN -4771
MT-TC -4522
TRMT10C -4481
POP1 -4049
MT-TA -3981
CPSF1 -3813
POP4 -3797
MT-TV -3652
MT-ND3 -3649
MT-ND1 -3616
TRMT1 -3444
EPRS1 -3185
MT-ATP8 -3067
NUP85 -3049
MT-TL1 -2976
MT-TS1 -2975
DDX1 -2786
MT-TF -2754
XPOT -2715
MT-CYB -2254
MT-ND5 -2166
MT-ATP6 -2096
MT-ND4L -2023
NSUN2 -1892
LAGE3 -1809
MT-TM -1516
RTCB -1471
TYW5 -1212
URM1 -1142
RANBP2 -820
TRMT12 -321
MT-RNR1 -300
MT-CO3 40
MT-CO2 48
RPPH1 88
MT-ND6 459
MT-CO1 684
TRMT112 738
TRIT1 758
NUP62 769
MT-ND4 840
TRDMT1 912
ADAT3 1101
TRMT5 1218
MT-RNR2 2112
QTRT2 2329
RPP14 3005
NUP37 3074
NUP98 3101
PRORP 3390
DUS2 3467
PUS3 3643
POP7 4149
RTRAF 4178
HSD17B10 4182
ZBTB8OS 4258
NUP50 4521
CTU1 4623
RAE1 5164
TRMT6 5698
SEC13 5748
CLP1 6589
TRMT10A 6869
TSEN34 7508
TRMT9B 7722
NUP214 7921
NUP58 8820


Post-translational protein phosphorylation

Post-translational protein phosphorylation
842
set Post-translational protein phosphorylation
setSize 70
pANOVA 2.94e-07
s.dist 0.354
p.adjustANOVA 4.61e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
FAM20A 9524
VCAN 9505
F5 9485
FAM20C 9421
LAMC1 9387
CKAP4 9370
APLP2 9347
QSOX1 9298
FSTL3 9290
PCSK9 9208
APP 9177
SERPINA1 9168
LGALS1 9032
PNPLA2 8939
NUCB1 8883
ADAM10 8791
TGOLN2 8714
TIMP1 8677
P4HB 8440
DNAJC3 8435

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FAM20A 9524
VCAN 9505
F5 9485
FAM20C 9421
LAMC1 9387
CKAP4 9370
APLP2 9347
QSOX1 9298
FSTL3 9290
PCSK9 9208
APP 9177
SERPINA1 9168
LGALS1 9032
PNPLA2 8939
NUCB1 8883
ADAM10 8791
TGOLN2 8714
TIMP1 8677
P4HB 8440
DNAJC3 8435
FUCA2 8304
FN1 8284
GAS6 8063
LTBP1 7962
FSTL1 7908
CALU 7894
MELTF 7197
IGFBP7 6545
ANO8 6099
LAMB1 5966
PDIA6 5882
APOA2 5879
SDC2 5397
TMEM132A 5245
PRKCSH 5220
FBN1 4836
C4A 4466
SERPINA10 3902
ALB 3668
MFGE8 3534
KTN1 3363
MBTPS1 2966
CST3 2206
HSP90B1 2059
SHISA5 1269
TF 1102
LAMB2 501
APOE 218
CP -1561
CSF1 -2061
MSLN -2192
ENAM -2373
SERPIND1 -2722
TNC -4039
BMP4 -4081
MGAT4A -5680
MIA3 -6245
FGF23 -6622
ITIH2 -6820
GOLM1 -6842
MXRA8 -7477
IGFBP4 -7582
APOL1 -7657
MEN1 -8538
IGFBP3 -9455
WFS1 -9774
PROC -10098
RCN1 -10766
C3 -12262
PRSS23 -12288


CLEC7A (Dectin-1) signaling

CLEC7A (Dectin-1) signaling
131
set CLEC7A (Dectin-1) signaling
setSize 97
pANOVA 3.16e-07
s.dist 0.3
p.adjustANOVA 4.9e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
UBE2D1 9187
SYK 9076
PRKCD 9008
PYCARD 8638
CDC34 8611
PSMB7 8485
PSMD4 8402
PSME3 8251
PPP3R1 8175
PSMB5 8101
CHUK 7966
PSMD6 7846
UBA3 7767
PSMD9 7620
UBE2M 7477
PSMD2 7411
PSMA1 7329
PSMD1 7241
PSMB3 7171
PSMA7 7096

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
UBE2D1 9187
SYK 9076
PRKCD 9008
PYCARD 8638
CDC34 8611
PSMB7 8485
PSMD4 8402
PSME3 8251
PPP3R1 8175
PSMB5 8101
CHUK 7966
PSMD6 7846
UBA3 7767
PSMD9 7620
UBE2M 7477
PSMD2 7411
PSMA1 7329
PSMD1 7241
PSMB3 7171
PSMA7 7096
PSMC1 7021
PPP3CB 7005
TAB2 6964
PSMB6 6813
NFKBIA 6807
PSMF1 6659
CARD9 6648
UBB 6639
PSMC6 6635
PSMD12 6556
AHCYL1 6456
NFKB1 6277
PSMD11 6231
PPP3CA 6217
FBXW11 6196
PDPK1 6136
PSMA6 5970
PSMD7 5963
PSMD13 5948
BCL10 5849
ITPR2 5842
PSMD8 5757
TAB1 5681
UBE2V1 5637
CLEC7A 5608
IKBKG 5377
PSMA2 5339
PLCG2 5006
IL1B 4807
UBE2D2 4657
PSMD3 4618
UBC 4439
SEM1 4348
SKP1 4287
PSMB2 4084
RELB 3721
PSMD5 3426
PSMB1 3374
TAB3 3160
PSMD14 2611
PSMC2 2598
PSMB4 2523
MAP3K7 2395
PSMC3 1976
UBE2N 1936
PSMD10 1559
UBA52 1121
TRAF6 -229
PSMA4 -616
PSMC5 -863
NFKB2 -1165
RELA -1803
CALM1 -2081
PSMB8 -3076
BTRC -4924
PSMA3 -5285
IKBKB -5386
PSMB10 -5735
PSMA5 -6053
PSME4 -6087
RPS27A -6938
PSMA8 -7606
ITPR1 -7629
SRC -8820
PSMC4 -9127
NFATC1 -9147
PSME1 -9991
ITPR3 -10308
PSME2 -10336
MALT1 -10920
PSMB9 -11324
CUL1 -11330
CASP8 -11336
MAP3K14 -11702
CARD11 -12160
NFATC3 -12177
NFATC2 -12294


DNA strand elongation

DNA strand elongation
247
set DNA strand elongation
setSize 32
pANOVA 3.21e-07
s.dist -0.522
p.adjustANOVA 4.91e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
MCM3 -12200
POLA1 -12150
MCM7 -12129
RPA1 -12004
RFC5 -11712
POLA2 -11575
LIG1 -11053
MCM8 -10944
RFC4 -10702
FEN1 -10593
GINS3 -10508
RFC3 -10489
POLD2 -10351
GINS4 -10236
PRIM1 -10191
MCM6 -9715
RPA3 -8911
MCM4 -8701
RFC1 -7437
MCM5 -7292

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MCM3 -12200
POLA1 -12150
MCM7 -12129
RPA1 -12004
RFC5 -11712
POLA2 -11575
LIG1 -11053
MCM8 -10944
RFC4 -10702
FEN1 -10593
GINS3 -10508
RFC3 -10489
POLD2 -10351
GINS4 -10236
PRIM1 -10191
MCM6 -9715
RPA3 -8911
MCM4 -8701
RFC1 -7437
MCM5 -7292
MCM2 -7223
RPA2 -6306
PCNA -5969
PRIM2 -5575
GINS2 -4815
GINS1 -4401
DNA2 -2858
CDC45 -2659
POLD1 204
RFC2 4948
POLD4 6336
POLD3 8885


Signaling by BRAF and RAF fusions

Signaling by BRAF and RAF fusions
1075
set Signaling by BRAF and RAF fusions
setSize 57
pANOVA 3.3e-07
s.dist 0.391
p.adjustANOVA 4.98e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
MAP2K1 9063
PAPSS1 9003
QKI 8996
AGTRAP 8956
MAPK3 8953
ITGA2B 8893
APBB1IP 8744
MARK3 8697
TLN1 8525
ARRB2 8490
AP3B1 8365
ITGB3 8291
FN1 8284
IQGAP1 8152
ATG7 8134
RAF1 7879
MAPK1 7493
BCL2L11 7384
VCL 7328
RAP1A 7305

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MAP2K1 9063
PAPSS1 9003
QKI 8996
AGTRAP 8956
MAPK3 8953
ITGA2B 8893
APBB1IP 8744
MARK3 8697
TLN1 8525
ARRB2 8490
AP3B1 8365
ITGB3 8291
FN1 8284
IQGAP1 8152
ATG7 8134
RAF1 7879
MAPK1 7493
BCL2L11 7384
VCL 7328
RAP1A 7305
KDM7A 6855
MAP2K2 6794
VWF 6641
YWHAB 6385
AGGF1 6191
NRAS 5363
FXR1 5308
CSK 5219
TRAK1 5022
FAM114A2 4963
KSR1 4167
LMNA 3887
SND1 3849
TRIM24 3806
KRAS 3702
KIAA1549 3618
RAP1B 3206
JAK2 2691
ARAF 2644
CLCN6 2232
ARRB1 1998
CAMK2G 1921
BRAF 1308
FAM131B -734
CALM1 -2081
KSR2 -3361
HRAS -3382
CNKSR2 -4781
AKAP9 -5020
CNKSR1 -7089
SRC -8820
ZC3HAV1 -10064
MPRIP -10959
TENT4A -11168
PEBP1 -11270
CAMK2D -11816
AGK -12120


Intracellular signaling by second messengers

Intracellular signaling by second messengers
573
set Intracellular signaling by second messengers
setSize 273
pANOVA 3.32e-07
s.dist 0.179
p.adjustANOVA 4.98e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
PPARG 9522
PRKACA 9429
LAMTOR1 9411
GRB2 9304
RCOR1 9073
AGO4 9070
PHC2 9043
PIK3CB 9038
VAPA 9033
PRKCD 9008
ADCY3 8984
KL 8963
MAPK3 8953
TGFA 8889
HGF 8863
MKRN1 8817
RAC1 8793
RRAGD 8753
RNF146 8696
FOXO3 8682

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PPARG 9522
PRKACA 9429
LAMTOR1 9411
GRB2 9304
RCOR1 9073
AGO4 9070
PHC2 9043
PIK3CB 9038
VAPA 9033
PRKCD 9008
ADCY3 8984
KL 8963
MAPK3 8953
TGFA 8889
HGF 8863
MKRN1 8817
RAC1 8793
RRAGD 8753
RNF146 8696
FOXO3 8682
SNAI1 8645
PRKAR1A 8607
IRS2 8569
LAMTOR5 8498
RHOG 8487
PSMB7 8485
PTEN 8460
PSMD4 8402
INSR 8282
PSME3 8251
PPP2CA 8234
EGF 8179
TRIM27 8142
MYD88 8136
CAMKK2 8125
PSMB5 8101
WWP2 8013
CHUK 7966
PRKAR1B 7918
VAV1 7896
AKT1S1 7865
PSMD6 7846
PIK3AP1 7811
GSK3A 7760
PPP2CB 7712
CASP9 7685
RHEB 7669
PSMD9 7620
LAMTOR3 7574
LAMTOR2 7567
MAPK1 7493
IER3 7463
PSMD2 7411
PSMA1 7329
PSMD1 7241
PSMB3 7171
IL1RAP 7150
PSMA7 7096
PSMC1 7021
BAD 6892
PSMB6 6813
PPP2R5B 6774
PRKAR2B 6741
PSMF1 6659
UBB 6639
PSMC6 6635
GSK3B 6634
PSMD12 6556
AHCYL1 6456
PIP5K1B 6450
FOXO4 6391
CSNK2A2 6388
USP7 6323
CAMKK1 6317
RRAGA 6244
PSMD11 6231
NEDD4 6201
CSNK2A1 6199
PRKAR2A 6166
PDPK1 6136
IRAK1 6131
HDAC7 6122
PIP5K1A 6110
GRK2 6068
PIK3CD 6046
AREG 5977
PSMA6 5970
PSMD7 5963
PSMD13 5948
PPP2R5A 5897
PDE1B 5874
PDGFRA 5858
ITPR2 5842
PSMD8 5757
MAF1 5723
GAB1 5679
AGO1 5654
HDAC2 5482
CBX8 5448
PSMA2 5339
PTPN11 5314
PDGFA 5293
ADCY4 5270
RAC2 5163
MAPKAP1 5057
HBEGF 5013
PIK3R2 5010
RRAGC 4954
HDAC5 4710
HDAC3 4673
PIK3CA 4629
PSMD3 4618
PPP2R1A 4589
CDKN1A 4511
LAMTOR4 4441
UBC 4439
SEM1 4348
MDM2 4312
PSMB2 4084
CBX6 4033
CSNK2B 3969
FGF2 3920
NRG1 3750
JUN 3722
STRN 3695
PHLPP1 3658
AKT1 3614
RNF2 3513
PSMD5 3426
PIP5K1C 3419
PSMB1 3374
IL1RL1 3175
EGR1 3124
GATAD2A 3075
AGO2 2995
SLC38A9 2807
EPGN 2662
PSMD14 2611
PSMC2 2598
PSMB4 2523
PPP2R5D 2421
CBX4 2222
ATF2 2085
PSMC3 1976
CAMK2G 1921
EREG 1888
IRS1 1741
MECOM 1687
PSMD10 1559
XIAP 1407
PRKCA 1132
UBA52 1121
REST 865
RPS6KB2 700
HDAC1 587
IL33 445
AKT2 433
MLST8 376
ATN1 234
ADCY9 123
CD86 -14
FRK -24
TRAF6 -229
PPP2R1B -241
ERBB3 -472
TNKS2 -499
MBD3 -528
PSMA4 -616
PPP2R5E -680
NBEA -703
RRAGB -713
TSC2 -804
PSMC5 -863
AGO3 -1011
STUB1 -1032
CREB1 -1378
ADCY6 -1608
GATAD2B -1759
RBBP4 -1870
NRG4 -1875
CALM1 -2081
PIP4K2A -2365
SUZ12 -2409
ADCY2 -2896
MTA1 -3005
PSMB8 -3076
ADCY7 -3286
FGFR4 -3293
FRS2 -3433
CD19 -3843
RING1 -4063
FGF7 -4247
CHD4 -4515
TNRC6B -4518
CBX2 -4617
PTENP1 -5280
PSMA3 -5285
FGFR1 -5352
TNRC6A -5613
PSMB10 -5735
SCMH1 -5839
TRIB3 -5843
PSMA5 -6053
PSME4 -6087
SALL4 -6112
FOXO6 -6367
FGF23 -6622
USP13 -6737
NR4A1 -6756
CD80 -6841
KPNA2 -6910
RPS27A -6938
MTA2 -7317
TRAT1 -7535
PSMA8 -7606
ITPR1 -7629
PIP4K2B -7788
PRKCE -8001
PHC3 -8152
CDKN1B -8207
ADCY5 -8235
PHC1 -8402
PDGFB -8577
FGF22 -8607
PML -8693
TNKS -8738
FGF9 -8761
SRC -8820
ESR1 -9122
PSMC4 -9127
ESR2 -9250
EED -9348
KDM1A -9430
MTA3 -9433
ICOS -9434
FOXO1 -9465
PIK3R1 -9505
RICTOR -9670
CHD3 -9737
EZH2 -9741
MTOR -9767
BMI1 -9829
CAMK4 -9956
PSME1 -9991
CD28 -10202
ITPR3 -10308
PSME2 -10336
MIR25 -10350
PRKX -10428
RPTOR -10464
OTUD3 -10763
TP53 -10893
KIT -11004
THEM4 -11069
PLCG1 -11120
CNOT6L -11248
PPP2R5C -11265
PSMB9 -11324
PIP4K2C -11371
PDGFRB -11545
FYN -11675
FGFR2 -11785
CAMK2D -11816
TNRC6C -11828
LCK -11838
AKT3 -11849
PHLPP2 -11948
PRKACB -11959
PRR5 -11985
MOV10 -11991
PIK3R3 -12015
RBBP7 -12155
ERBB2 -12320


Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
1006
set Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
setSize 124
pANOVA 3.67e-07
s.dist 0.264
p.adjustANOVA 5.45e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
ETFA 8658
NDUFB3 8430
SDHC 8390
NDUFB9 8237
NDUFAF1 8167
UQCRH 8073
ETFDH 8052
UQCRC1 7859
COX7A2L 7719
ETFB 7688
ATP5PD 7637
SDHB 7587
NDUFB1 7578
ATP5PB 7551
NDUFAF3 6981
SDHD 6963
UQCR11 6907
TIMMDC1 6822
ATP5F1C 6687
COX8A 6611

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ETFA 8658
NDUFB3 8430
SDHC 8390
NDUFB9 8237
NDUFAF1 8167
UQCRH 8073
ETFDH 8052
UQCRC1 7859
COX7A2L 7719
ETFB 7688
ATP5PD 7637
SDHB 7587
NDUFB1 7578
ATP5PB 7551
NDUFAF3 6981
SDHD 6963
UQCR11 6907
TIMMDC1 6822
ATP5F1C 6687
COX8A 6611
ATP5MF 6519
ATP5F1B 6497
NDUFA4 6459
ATP5F1A 6441
ATP5PF 6373
NDUFS1 6348
UQCRFS1 6325
COX5B 6207
NDUFS5 6178
COX5A 6168
ATP5F1E 6142
NDUFC2 6093
NDUFS2 6080
NDUFA6 6009
ATP5MC3 5906
UQCRC2 5852
NDUFB10 5812
NDUFAB1 5759
NDUFA1 5718
COX6B1 5667
NDUFA7 5623
ATP5MG 5512
NDUFC1 5343
NDUFV3 5214
COX6A1 5095
NDUFA2 4966
ECSIT 4918
NDUFA8 4804
ATP5PO 4794
NDUFB4 4553
COX7B 4465
TACO1 4406
UQCR10 4378
NDUFV2 4288
NDUFA13 4244
NDUFB6 4218
COX4I1 4191
NDUFS6 4155
COQ10B 3989
NDUFS4 3986
NDUFB5 3892
UQCRB 3834
SURF1 3532
CYC1 3047
ATP5F1D 2968
UQCRQ 2960
ATP5MC2 2956
NDUFAF7 2726
ATP5ME 2664
NDUFB7 2292
NDUFAF2 2133
NDUFS7 2118
NDUFA11 1458
NDUFB11 1172
NDUFB8 965
UCP2 913
NDUFS3 884
MT-ND4 840
COX6C 706
MT-CO1 684
COX7C 564
NDUFA3 503
MT-ND6 459
COX16 132
NDUFS8 81
MT-CO2 48
MT-CO3 40
ACAD9 -879
CYCS -1334
COX14 -1496
NDUFA12 -1728
MT-ATP6 -2096
MT-ND5 -2166
MT-CYB -2254
NDUFAF6 -2331
MT-ATP8 -3067
MT-ND1 -3616
MT-ND3 -3649
SCO2 -4351
SLC25A27 -4356
NDUFB2 -4446
SLC25A14 -4642
NDUFA5 -4723
COX20 -5018
SDHA -5579
COX18 -6126
MT-ND2 -6560
COX19 -6882
NDUFA10 -6994
DMAC2L -7274
ATP5MC1 -7616
TMEM126B -8346
NDUFA9 -8864
NDUFAF5 -9499
SCO1 -9819
PM20D1 -9905
NDUFAF4 -10063
LRPPRC -10081
UCP3 -10214
TRAP1 -10796
COQ10A -11405
NDUFV1 -11466
COX11 -11539
NUBPL -11628


C-type lectin receptors (CLRs)

C-type lectin receptors (CLRs)
120
set C-type lectin receptors (CLRs)
setSize 129
pANOVA 3.78e-07
s.dist 0.259
p.adjustANOVA 5.54e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
PRKACA 9429
UBE2D1 9187
CLEC4D 9185
SYK 9076
PRKCD 9008
PYCARD 8638
CDC34 8611
PSMB7 8485
PSMD4 8402
CLEC4E 8324
CLEC4A 8260
PSME3 8251
PAK1 8230
PAK2 8185
PPP3R1 8175
FCER1G 8131
PSMB5 8101
CHUK 7966
RAF1 7879
PSMD6 7846

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PRKACA 9429
UBE2D1 9187
CLEC4D 9185
SYK 9076
PRKCD 9008
PYCARD 8638
CDC34 8611
PSMB7 8485
PSMD4 8402
CLEC4E 8324
CLEC4A 8260
PSME3 8251
PAK1 8230
PAK2 8185
PPP3R1 8175
FCER1G 8131
PSMB5 8101
CHUK 7966
RAF1 7879
PSMD6 7846
LYN 7809
ICAM3 7808
UBA3 7767
PSMD9 7620
UBE2M 7477
PSMD2 7411
PSMA1 7329
PSMD1 7241
PSMB3 7171
PSMA7 7096
PSMC1 7021
PPP3CB 7005
TAB2 6964
PSMB6 6813
NFKBIA 6807
CLEC6A 6730
PSMF1 6659
CARD9 6648
UBB 6639
PSMC6 6635
MUC1 6573
PSMD12 6556
AHCYL1 6456
NFKB1 6277
PSMD11 6231
PPP3CA 6217
FBXW11 6196
PDPK1 6136
EP300 6129
PSMA6 5970
PSMD7 5963
PSMD13 5948
BCL10 5849
ITPR2 5842
PSMD8 5757
TAB1 5681
UBE2V1 5637
CLEC7A 5608
IKBKG 5377
NRAS 5363
PSMA2 5339
PLCG2 5006
IL1B 4807
UBE2D2 4657
PSMD3 4618
UBC 4439
SEM1 4348
SKP1 4287
PSMB2 4084
RELB 3721
KRAS 3702
PSMD5 3426
CREBBP 3423
PSMB1 3374
TAB3 3160
PSMD14 2611
PSMC2 2598
PSMB4 2523
MAP3K7 2395
PSMC3 1976
UBE2N 1936
PSMD10 1559
UBA52 1121
TRAF6 -229
PSMA4 -616
PSMC5 -863
NFKB2 -1165
RELA -1803
CALM1 -2081
MUCL1 -2211
MUC6 -2977
PSMB8 -3076
MUC4 -3191
HRAS -3382
MUC16 -4104
PAK3 -4184
MUC5B -4613
BTRC -4924
PSMA3 -5285
CLEC10A -5299
IKBKB -5386
PSMB10 -5735
MUC20 -5962
PSMA5 -6053
PSME4 -6087
RPS27A -6938
PSMA8 -7606
ITPR1 -7629
SRC -8820
PSMC4 -9127
CD209 -9143
NFATC1 -9147
PSME1 -9991
ITPR3 -10308
PSME2 -10336
MUC12 -10704
MALT1 -10920
PSMB9 -11324
CUL1 -11330
CASP8 -11336
RPS6KA5 -11594
FYN -11675
MAP3K14 -11702
CLEC4C -11809
PRKACB -11959
ICAM2 -12026
CARD11 -12160
NFATC3 -12177
NFATC2 -12294


RNA Polymerase II Transcription

RNA Polymerase II Transcription
909
set RNA Polymerase II Transcription
setSize 1204
pANOVA 4.09e-07
s.dist -0.0867
p.adjustANOVA 5.94e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
FASLG -12371
TFDP2 -12364
RUNX3 -12352
ERBB2 -12320
NFATC2 -12294
ZNF599 -12232
PTPN4 -12220
RAD1 -12206
GATA3 -12191
ZNF287 -12168
ZNF3 -12165
RBBP7 -12155
YES1 -12142
PRKCQ -12127
AUTS2 -12089
ZNF530 -12068
MDC1 -12059
WRN -12047
TP53RK -12040
ZNF74 -12012

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FASLG -12371.0
TFDP2 -12364.0
RUNX3 -12352.0
ERBB2 -12320.0
NFATC2 -12294.0
ZNF599 -12232.0
PTPN4 -12220.0
RAD1 -12206.0
GATA3 -12191.0
ZNF287 -12168.0
ZNF3 -12165.0
RBBP7 -12155.0
YES1 -12142.0
PRKCQ -12127.0
AUTS2 -12089.0
ZNF530 -12068.0
MDC1 -12059.0
WRN -12047.0
TP53RK -12040.0
ZNF74 -12012.0
RPA1 -12004.0
MOV10 -11991.0
PRR5 -11985.0
RORA -11979.0
ANAPC1 -11962.0
ZNF461 -11956.0
FANCI -11927.0
ZNF33B -11911.0
ZNF549 -11908.0
ZNF250 -11889.0
DLL1 -11885.0
SMAD7 -11872.0
GLS -11862.0
NUAK1 -11853.0
AKT3 -11849.0
ZNF70 -11832.0
TNRC6C -11828.0
CAMK2D -11816.0
ZNF43 -11813.0
ZNF682 -11811.0
ZNF500 -11806.0
DYRK2 -11799.0
DGCR8 -11798.0
ZNF286A -11794.0
ZNF571 -11792.0
ZNF607 -11784.0
PARP1 -11764.0
SMAD3 -11745.0
CCND2 -11734.0
ZNF620 -11732.0
STAT1 -11727.0
RFC5 -11712.0
CCNE1 -11707.0
ZNF736 -11692.0
ZNF696 -11688.0
SMARCD1 -11679.0
ZNF568 -11661.0
ZNF554 -11652.0
PPP1R13B -11636.0
BRIP1 -11605.0
ZNF337 -11599.0
NR2C2AP -11589.0
ZNF724 -11586.0
ZNF517 -11582.0
ZNF570 -11569.0
FANCC -11548.0
COX11 -11539.0
DDB2 -11530.0
ZNF569 -11521.0
ZNF235 -11519.0
ATRIP -11486.0
MSH2 -11484.0
ZNF566 -11481.0
ZNF496 -11478.0
JMY -11472.0
ZNF707 -11464.0
ZNF30 -11462.0
KRBOX4 -11452.0
ZNF419 -11446.0
ZNF740 -11444.0
RAD9A -11435.0
ZNF136 -11433.0
RNPS1 -11427.0
FANCD2 -11424.0
RAD51D -11415.0
CENPJ -11406.0
ZNF773 -11396.0
PIP4K2C -11371.0
ZNF138 -11364.0
SUPT16H -11359.0
ZNF211 -11357.0
ZNF551 -11356.0
ZNF202 -11351.0
ZNF510 -11341.0
CUL1 -11330.0
PSMB9 -11324.0
ZNF600 -11320.0
CDC23 -11304.0
ZNF383 -11291.0
ZNF660 -11282.0
PPP2R5C -11265.0
CDK4 -11256.0
CNOT6L -11248.0
ZKSCAN8 -11246.0
ZNF528 -11244.0
ZNF248 -11241.0
ZNF649 -11216.0
ZNF354C -11213.0
ZNF14 -11212.0
ZNF343 -11182.0
ZFP30 -11171.0
RUNX2 -11163.0
SSRP1 -11162.0
ATM -11148.0
ZNF75D -11137.0
ZNF550 -11136.0
ZNF584 -11134.0
ZNF133 -11128.0
SKI -11113.0
ZNF519 -11101.0
ZNF540 -11097.0
RNMT -11086.0
WWOX -11085.0
ZNF77 -11084.0
PLXNA4 -11083.0
ZNF184 -11077.0
SRSF5 -11067.0
PCBP4 -11063.0
ZNF548 -11049.0
ITGA4 -11043.0
ZIK1 -11040.0
ZNF19 -11034.0
ZNF678 -11020.0
ZNF621 -11018.0
KIT -11004.0
BRD1 -10991.0
PMAIP1 -10986.0
ZNF324B -10972.0
ANAPC5 -10967.0
ZNF226 -10966.0
ZNF432 -10951.0
ZNF703 -10910.0
ZNF441 -10905.0
TP53 -10893.0
ZNF10 -10857.0
MECP2 -10855.0
ITGAL -10847.0
TP63 -10842.0
ZNF302 -10830.0
KAT2A -10771.0
L3MBTL2 -10770.0
KMT2A -10725.0
ZNF257 -10712.0
RFC4 -10702.0
ZNF23 -10692.0
ZNF180 -10670.0
ATAD2 -10660.0
ZNF253 -10652.0
PRMT6 -10628.0
NR3C2 -10625.0
FBXO32 -10607.0
ZNF585B -10598.0
ZNF266 -10587.0
DAXX -10575.0
ZNF563 -10567.0
ZFP1 -10563.0
ZNF790 -10520.0
MAF -10499.0
SIN3A -10493.0
ZNF420 -10490.0
RFC3 -10489.0
ZNF675 -10478.0
ZNF529 -10469.0
RPTOR -10464.0
ZNF544 -10460.0
ZNF749 -10456.0
ZNF473 -10444.0
SMYD2 -10431.0
LSM11 -10415.0
ZNF595 -10393.0
CTLA4 -10363.0
ATR -10354.0
ZNF92 -10349.0
SMURF2 -10340.0
PSME2 -10336.0
ZNF112 -10327.0
NR1D2 -10325.0
RAD17 -10307.0
LDB1 -10303.0
ZNF778 -10297.0
ZNF680 -10286.0
AXIN1 -10285.0
IFNG -10277.0
ZNF446 -10274.0
GPAM -10241.0
THOC1 -10238.0
ZNF799 -10216.0
ZFPM1 -10195.0
TCF7 -10173.0
ZFP14 -10160.0
ZNF212 -10128.0
WWP1 -10106.0
TGIF2 -10105.0
ZNF737 -10092.0
ZC3H8 -10090.0
LRPPRC -10081.0
ING5 -10037.0
MLLT3 -10022.0
ZNF626 -10014.0
SRSF11 -10002.0
PSME1 -9991.0
ZNF224 -9977.0
PERP -9973.0
NFYB -9964.0
RBL1 -9959.0
CAMK4 -9956.0
NOP2 -9952.0
MGA -9948.0
ZNF436 -9945.0
EPC1 -9926.0
NR2C1 -9913.0
ZNF26 -9910.0
ZNF45 -9897.0
ZNF483 -9883.0
ZNF324 -9879.0
ZNF596 -9874.0
ZNF708 -9864.0
ZNF573 -9862.0
ZNF582 -9837.0
BMI1 -9829.0
ZNF664 -9828.0
SCO1 -9819.0
ZNF227 -9818.0
ZNF485 -9810.0
ZNF263 -9806.0
GATA2 -9800.0
MED15 -9778.0
MTOR -9767.0
HEY2 -9752.0
EZH2 -9741.0
CHD3 -9737.0
ZNF157 -9718.0
ZNF583 -9711.0
ZNF311 -9705.0
BRD2 -9688.0
RICTOR -9670.0
ZNF704 -9660.0
ZNF793 -9654.0
ZNF597 -9642.0
ZNF431 -9641.0
ZNF470 -9630.0
ZFP90 -9613.0
TXNIP -9600.0
ZNF354B -9598.0
ZNF684 -9580.0
ZNF614 -9572.0
ZNF689 -9559.0
NCBP2 -9558.0
NPM1 -9532.0
ZNF484 -9525.0
ZSCAN25 -9513.0
ZFP69 -9488.0
CCNT1 -9469.0
FOXO1 -9465.0
IGFBP3 -9455.0
ZNF506 -9443.0
CPSF4 -9416.0
ZNF41 -9405.0
ZNF17 -9349.0
EED -9348.0
TRPC3 -9343.0
ZNF767P -9339.0
ZNF625 -9336.0
MAGOHB -9327.0
ZNF606 -9322.0
INTS4 -9307.0
CBX5 -9272.0
ESR2 -9250.0
PRMT1 -9229.0
MED27 -9191.0
TBP -9167.0
ZNF141 -9154.0
ZNF677 -9144.0
PSMC4 -9127.0
ESR1 -9122.0
ZNF727 -9121.0
ZNF782 -9113.0
ZNF738 -9086.0
ZNF709 -9071.0
ZNF699 -9037.0
ZNF317 -9010.0
ZNF439 -9000.0
ZNF160 -8989.0
ZNF567 -8988.0
NR1D1 -8980.0
SESN1 -8962.0
ICE2 -8945.0
RPAP2 -8928.0
ZNF721 -8922.0
RPA3 -8911.0
ZNF416 -8903.0
ZNF681 -8899.0
SRSF7 -8892.0
SMARCC1 -8880.0
SIRT3 -8857.0
PRDM1 -8856.0
ZNF792 -8839.0
TRIM33 -8823.0
SRC -8820.0
ZNF433 -8780.0
ZNF79 -8769.0
ZNF140 -8760.0
ZNF619 -8735.0
ZNF440 -8730.0
AIFM2 -8727.0
ZNF717 -8709.0
ZNF331 -8698.0
PML -8693.0
EHMT1 -8692.0
MNAT1 -8687.0
TGIF1 -8682.0
ZNF274 -8667.0
NR2C2 -8630.0
MED10 -8579.0
RORC -8573.0
E2F5 -8568.0
EHMT2 -8558.0
MEN1 -8538.0
ZFP37 -8513.0
FOXP3 -8503.0
ZNF234 -8487.0
ZNF300 -8481.0
TAF1 -8476.0
ZNF559 -8467.0
L3MBTL1 -8461.0
PHC1 -8402.0
CDK13 -8392.0
ICE1 -8382.0
MAPKAPK5 -8364.0
SNAPC3 -8359.0
SMAD4 -8351.0
HDAC6 -8337.0
UPF3B -8288.0
SKP2 -8279.0
HES1 -8266.0
CDKN1B -8207.0
PRKAB2 -8172.0
PHC3 -8152.0
ZKSCAN3 -8126.0
MEAF6 -8105.0
LEF1 -8076.0
TAF4B -8069.0
ZNF720 -8041.0
ZNF665 -7990.0
ZNF175 -7950.0
THOC3 -7934.0
FIP1L1 -7928.0
MRE11 -7923.0
GLI3 -7910.0
INTS7 -7902.0
ZNF726 -7889.0
ZNF641 -7885.0
ZNF688 -7872.0
BBC3 -7864.0
CDC7 -7855.0
ZNF135 -7853.0
ZNF521 -7834.0
ZNF12 -7825.0
RGCC -7821.0
ZNF585A -7814.0
ZNF671 -7797.0
PIP4K2B -7788.0
ERCC3 -7783.0
ZNF75A -7752.0
RBL2 -7743.0
ZNF382 -7731.0
TNFRSF18 -7726.0
WDR33 -7715.0
GLS2 -7702.0
ZNF702P -7701.0
ZNF771 -7686.0
ZNF2 -7673.0
ZNF320 -7647.0
ZNF273 -7623.0
PSMA8 -7606.0
ZNF577 -7605.0
ZNF418 -7559.0
ZNF791 -7534.0
RBM14 -7497.0
ACTL6A -7468.0
ZNF264 -7412.0
ANAPC2 -7407.0
RBM8A -7393.0
MED24 -7387.0
YAF2 -7378.0
RAD50 -7373.0
TAF6 -7352.0
YWHAQ -7340.0
MTA2 -7317.0
ZNF711 -7253.0
ZNF195 -7249.0
NABP2 -7240.0
BRPF1 -7218.0
TCF3 -7215.0
IL2RA -7161.0
GAMT -7054.0
ZNF785 -7032.0
ZNF777 -6997.0
CCND1 -6970.0
RPS27A -6938.0
ZNF764 -6912.0
ZNF786 -6907.0
ZNF223 -6903.0
ZNF425 -6900.0
ZNF268 -6887.0
COX19 -6882.0
MLH1 -6872.0
ZFP28 -6824.0
MED23 -6787.0
NR4A1 -6756.0
SUPT5H -6716.0
PIDD1 -6647.0
ANAPC4 -6644.0
ZNF33A -6630.0
ZNF691 -6627.0
BRPF3 -6615.0
ZKSCAN7 -6609.0
FBXW7 -6600.0
GAD2 -6585.0
ZNF415 -6564.0
H2BU1 -6555.0
DDX39A -6544.0
INTS9 -6543.0
CDK6 -6465.0
ZNF480 -6459.0
TAF15 -6454.0
CSTF2 -6444.0
RHNO1 -6437.0
SUPT6H -6407.0
SRSF2 -6396.0
PPARD -6394.0
THRA -6387.0
ZNF616 -6382.0
TJP1 -6374.0
FOXO6 -6367.0
ZNF208 -6363.0
RPA2 -6306.0
NELFCD -6277.0
TFAP2E -6266.0
AGRP -6243.0
ZNF169 -6234.0
ZNF442 -6204.0
TCF7L2 -6185.0
ZNF610 -6184.0
CSTF2T -6171.0
RNF34 -6150.0
WWTR1 -6131.0
SYMPK -6129.0
COX18 -6126.0
CSTF1 -6113.0
KRBA1 -6098.0
PSME4 -6087.0
KMT2E -6073.0
CDC16 -6071.0
PSMA5 -6053.0
ZNF706 -6049.0
ZNF493 -6035.0
ZNF557 -5971.0
PCNA -5969.0
ZNF662 -5963.0
ZNF154 -5946.0
TAF2 -5945.0
ZNF543 -5942.0
NCBP1 -5853.0
ZNF398 -5842.0
SCMH1 -5839.0
NOC2L -5831.0
ZNF761 -5813.0
FYTTD1 -5794.0
E2F7 -5780.0
SETD1A -5744.0
PSMB10 -5735.0
ZNF713 -5668.0
ZNF514 -5664.0
ZNF718 -5657.0
ZNF101 -5614.0
TNRC6A -5613.0
MAMLD1 -5584.0
ZNF658 -5581.0
ZNF34 -5577.0
ZFP69B -5558.0
ZNF71 -5533.0
ZNF589 -5519.0
PMS2 -5514.0
ARID1B -5504.0
TNKS1BP1 -5490.0
MED30 -5484.0
ZNF25 -5459.0
ZNF417 -5416.0
SRSF6 -5402.0
BLK -5388.0
ZNF99 -5349.0
ZNF615 -5323.0
ZNF547 -5291.0
PSMA3 -5285.0
PHAX -5261.0
SRRT -5248.0
RABGGTB -5240.0
ZNF285 -5239.0
CDKN2A -5236.0
ZNF37A -5230.0
NOTCH4 -5229.0
CCNT2 -5205.0
BTG1 -5201.0
ANAPC7 -5181.0
ZKSCAN4 -5161.0
RARG -5153.0
ZNF443 -5146.0
RBBP8 -5105.0
NR4A3 -5082.0
TRIM28 -5056.0
SRRM1 -5050.0
PPARGC1B -5047.0
COX20 -5018.0
ZNF155 -5014.0
CDK2 -5006.0
ANAPC10 -5000.0
E2F6 -4979.0
SOCS4 -4974.0
ZNF124 -4952.0
ZNF430 -4837.0
ZNF546 -4802.0
TP73 -4754.0
ZNF692 -4722.0
ZNF700 -4710.0
BLM -4690.0
ZNF611 -4678.0
ZNF492 -4623.0
DHX38 -4620.0
CBX2 -4617.0
ZNF564 -4519.0
TNRC6B -4518.0
CHD4 -4515.0
TAF5 -4514.0
RPRD2 -4513.0
ZNF460 -4477.0
NR1I2 -4435.0
ZNF197 -4430.0
ZNF426 -4382.0
SCO2 -4351.0
CHEK2 -4350.0
SMARCE1 -4315.0
U2AF1L4 -4295.0
ZNF561 -4292.0
CNOT1 -4265.0
DDX39B -4243.0
SIN3B -4205.0
SIRT1 -4197.0
SMARCC2 -4137.0
PCGF2 -4135.0
RING1 -4063.0
RMI2 -4050.0
ZNF486 -4043.0
MED1 -4036.0
POLR2D -4024.0
ARID2 -3932.0
ZNF233 -3931.0
CDK9 -3927.0
YEATS4 -3919.0
NELFA -3886.0
CNOT7 -3880.0
SMARCB1 -3869.0
PRELID3A -3832.0
CPSF1 -3813.0
SNAPC5 -3794.0
TEAD2 -3774.0
ZNF334 -3744.0
ZSCAN32 -3733.0
ZNF215 -3708.0
NUDT21 -3702.0
PAX5 -3638.0
NR1H3 -3597.0
ZNF676 -3587.0
ZNF701 -3558.0
SESN3 -3546.0
GPX2 -3533.0
ZNF350 -3507.0
ZNF655 -3460.0
ZNF556 -3455.0
TOPBP1 -3450.0
CASP10 -3446.0
BARD1 -3419.0
BCL2L14 -3367.0
PCGF5 -3312.0
ZNF714 -3298.0
ZNF624 -3294.0
RXRB -3276.0
UXT -3252.0
PIN1 -3188.0
ZFP2 -3134.0
ZNF221 -3101.0
POLR2A -3092.0
PSMB8 -3076.0
ZNF670 -3075.0
CTSV -3036.0
PCF11 -3032.0
POLR2H -2942.0
TAF11 -2938.0
GTF2H4 -2916.0
GTF2H1 -2913.0
DNA2 -2858.0
CASP6 -2831.0
HIVEP3 -2798.0
RAD51 -2767.0
PLK2 -2748.0
ZNF555 -2741.0
SMARCA2 -2737.0
CNOT10 -2718.0
TTC5 -2650.0
ZNF490 -2630.0
ABCA6 -2612.0
TAF9B -2599.0
SMURF1 -2591.0
ZNF605 -2576.0
ZNF18 -2548.0
POLR2B -2523.0
ZNF772 -2509.0
CHEK1 -2481.0
CASP2 -2471.0
RABGGTA -2462.0
KAT2B -2414.0
SUZ12 -2409.0
SNRPB -2400.0
DDIT4 -2395.0
SNRPF -2377.0
PIP4K2A -2365.0
H19 -2361.0
ZNF860 -2350.0
OCLN -2327.0
SRSF3 -2292.0
GTF2H3 -2235.0
FZR1 -2233.0
ZC3H11A -2210.0
ZNF839 -2202.0
ANAPC16 -2123.0
TSC1 -2118.0
CNOT2 -2090.0
CALM1 -2081.0
CDK8 -1971.0
INTS2 -1936.0
PHF20 -1921.0
KCTD1 -1890.0
RBBP4 -1870.0
HSPD1 -1860.0
TAF3 -1850.0
RELA -1803.0
POLR2K -1783.0
GATAD2B -1759.0
NR2F1 -1717.0
ZNF468 -1709.0
TAF4 -1698.0
RNU1-1 -1690.5
RFFL -1683.0
ZNF669 -1660.0
ZNF28 -1618.0
NR4A2 -1601.0
EXO1 -1586.0
COX14 -1496.0
BGLAP -1473.0
CHTOP -1387.0
CREB1 -1378.0
CDK12 -1356.0
ZNF750 -1354.0
CYCS -1334.0
CNOT4 -1286.0
SETD9 -1240.0
TCF12 -1233.0
MDM4 -1230.0
H2AZ2 -1209.0
CDK5R1 -1089.0
STUB1 -1032.0
ZNF627 -1022.0
AGO3 -1011.0
INTS5 -1001.0
ZNF562 -962.0
TCEA1 -943.0
ZNF565 -941.0
GPS2 -889.0
PSMC5 -863.0
MED6 -842.0
SNAPC4 -815.0
TSC2 -804.0
UBE2I -764.0
SKIL -725.0
MOBP -714.0
RRAGB -713.0
PCGF6 -689.0
ZNF558 -678.0
CDC27 -651.0
PSMA4 -616.0
NPPA -584.0
MAML2 -582.0
MBD3 -528.0
PABPN1 -526.0
ZNF716 -489.0
MEF2C -293.0
PPP2R1B -241.0
MED14 -203.0
RRM2 -183.0
ZNF587 -164.0
ZNF200 -154.0
HUS1 -145.0
ZNF222 -84.0
ZNF347 -31.0
BRD7 -10.0
LEO1 39.0
MT-CO3 40.0
MT-CO2 48.0
KMT2C 63.0
WDR61 77.0
COX16 132.0
WDR5 155.0
KLF4 157.0
INTS12 172.0
APOE 218.0
MED7 224.0
ABL1 226.0
TCF7L1 275.0
ZNF100 276.0
TRIAP1 281.0
MYB 302.0
CSTF3 309.0
ZNF776 367.0
NELFB 374.0
MLST8 376.0
CSF1R 394.0
POLR2I 396.0
PPP1R13L 399.0
AKT2 433.0
PLAGL1 446.0
CCNB1 467.0
NR3C1 511.0
YY1 537.0
SNAPC1 549.0
COX7C 564.0
CCNA1 585.0
HDAC1 587.0
ELL3 621.0
SNRPE 628.0
CLDN5 650.0
MT-CO1 684.0
BANP 687.0
COX6C 706.0
SETD1B 736.0
INTS1 766.0
CCNH 774.0
KAT6A 794.0
PPARA 813.0
AURKB 846.0
THOC2 911.0
RBBP5 1037.0
ZNF429 1053.0
MAGOH 1054.0
UBA52 1121.0
RPRD1B 1159.0
KMT2B 1179.0
GCK 1193.0
TAF9 1250.0
U2AF1 1287.0
PRKAB1 1302.0
KAT5 1314.0
ITCH 1318.0
ZNF394 1319.0
PRKAA1 1322.0
ZKSCAN5 1336.0
HDAC9 1359.0
AFF4 1369.0
THRB 1429.0
MED31 1462.0
POU2F1 1537.0
CDK1 1540.0
TPX2 1551.0
PSMD10 1559.0
ATXN3 1601.0
SFN 1615.0
POLR2C 1616.0
ELF1 1630.0
SNRPG 1646.0
SNRPD3 1675.0
CCNA2 1685.0
KCTD15 1758.0
TNFRSF10A 1815.0
PVALB 1839.0
NR1I3 1855.0
CCNC 1877.0
CAMK2G 1921.0
ZNF658B 1948.0
ZNF613 1957.0
CAV1 1969.0
PSMC3 1976.0
PRKAG2 2015.0
MED12 2034.0
CBFB 2078.0
ATF2 2085.0
CNOT11 2102.0
TAF7 2139.0
OPRM1 2161.0
ZKSCAN1 2166.0
CBX4 2222.0
NBN 2267.0
CHM 2273.0
HDAC10 2280.0
GTF2E1 2287.0
STK11 2289.0
MYC 2304.0
SARNP 2436.0
SRSF1 2514.0
PSMB4 2523.0
MED13 2533.0
PSMC2 2598.0
MYBL2 2601.0
ELF2 2606.0
PSMD14 2611.0
DEK 2676.0
GTF2A1 2713.0
SLU7 2727.0
NRBP1 2786.0
SLC38A9 2807.0
POMC 2855.0
E2F8 2856.0
ZNF471 2869.0
CCNK 2877.0
ZNF586 2878.0
SUPT4H1 2890.0
CDC26 2923.0
ZNF770 2964.0
GTF2H2 2984.0
AGO2 2995.0
VENTX 3057.0
GATAD2A 3075.0
HDAC8 3079.0
MED17 3084.0
RNGTT 3088.0
RAD9B 3090.0
BTG2 3111.0
KMT2D 3203.0
HTT 3209.0
MED4 3215.0
THOC6 3225.0
SESN2 3311.0
AURKA 3330.0
ZNF445 3333.0
CTR9 3344.0
PSMB1 3374.0
CPSF7 3391.0
CREBBP 3423.0
PSMD5 3426.0
PRDX2 3428.0
PAF1 3478.0
ZNF189 3487.0
NFYA 3506.0
POLR2G 3508.0
RNF2 3513.0
GTF2B 3515.0
RTF1 3526.0
ZNF205 3530.0
SURF1 3532.0
ERCC2 3547.0
SSU72 3574.0
PRMT5 3600.0
AKT1 3614.0
TAF8 3620.0
U2AF2 3663.0
KRAS 3702.0
FAS 3712.0
JUN 3722.0
ZNF668 3725.0
BIRC5 3738.0
ZNF667 3739.0
DPY30 3757.0
SRSF4 3814.0
MAPK11 3826.0
TMEM219 3845.0
NELFE 3860.0
GTF2H5 3874.0
ZNF354A 3889.0
RBX1 3934.0
ZNF747 3949.0
CSNK2B 3969.0
PPARGC1A 3988.0
ZNF333 4007.0
CBX6 4033.0
PSMB2 4084.0
COX4I1 4191.0
CASP1 4224.0
CTSL 4231.0
MAX 4243.0
POU2F2 4251.0
SKP1 4287.0
INTS10 4291.0
MDM2 4312.0
SEM1 4348.0
KCTD6 4371.0
SOD2 4390.0
MED26 4395.0
TACO1 4406.0
ING2 4415.0
UBC 4439.0
LAMTOR4 4441.0
COX7B 4465.0
CDKN1A 4511.0
TBL1XR1 4556.0
RPRD1A 4573.0
PPP2R1A 4589.0
SGK1 4595.0
POLR2F 4604.0
PSMD3 4618.0
NDRG1 4647.0
HDAC3 4673.0
ZNF552 4685.0
ZNF20 4697.0
NOTCH1 4704.0
HDAC5 4710.0
SMARCA4 4733.0
UBE2S 4746.0
ZNF774 4747.0
HDAC11 4756.0
CNOT6 4799.0
DLX6 4817.0
CBX3 4825.0
ARID1A 4830.0
AR 4840.0
CCNG1 4881.0
ZNF282 4892.0
SMAD2 4905.0
DDIT3 4906.0
RFC2 4948.0
GTF2F1 4951.0
RRAGC 4954.0
CDC25C 4969.0
H2AC20 4972.0
NR2F6 4984.0
ELL 5009.0
CDC73 5020.0
SNAPC2 5038.0
ZNF775 5041.0
MAPKAP1 5057.0
CTSK 5059.0
COX6A1 5095.0
UBE2C 5101.0
GPRIN1 5131.0
CCNE2 5143.0
TGFB1 5153.0
SNW1 5201.0
CDK7 5211.0
CRADD 5216.0
CASC3 5242.0
NOTCH2 5272.0
MED16 5278.0
POLR2L 5305.0
H2BC15 5312.0
PTPN11 5314.0
CNOT3 5320.0
SLBP 5337.0
PSMA2 5339.0
H2BC9 5394.0
MAML1 5404.0
ALYREF 5432.0
GTF2F2 5434.0
CBX8 5448.0
FOS 5460.0
USP9X 5464.0
PRKAG1 5476.0
HDAC2 5482.0
TP53BP2 5532.0
EAF1 5533.0
RYBP 5535.0
PBRM1 5566.0
G6PC 5568.0
YWHAZ 5624.0
AGO1 5654.0
COX6B1 5667.0
INTS6 5673.0
PF4 5707.0
PTPN1 5722.0
KDM5B 5736.0
RNF111 5749.0
PSMD8 5757.0
GTF2E2 5767.0
PRELID1 5790.0
HIPK1 5855.0
NCOR1 5887.0
IWS1 5894.0
BAX 5916.0
ESRRA 5943.0
PSMD13 5948.0
ZNF213 5950.0
THBS1 5951.0
PSMD7 5963.0
PSMA6 5970.0
STEAP3 5996.0
ASH2L 6001.0
ZNF385A 6014.0
BID 6020.0
H2AZ1 6036.0
HIPK2 6078.0
HDAC7 6122.0
EP300 6129.0
IRAK1 6131.0
PDPK1 6136.0
ANAPC11 6161.0
COX5A 6168.0
CTDP1 6180.0
CSNK2A1 6199.0
TIGAR 6204.0
COX5B 6207.0
MED25 6209.0
PSMD11 6231.0
INTS3 6232.0
RRAGA 6244.0
BRCA1 6248.0
NFKB1 6277.0
GP1BA 6279.0
GPI 6284.0
THOC7 6293.0
E2F4 6300.0
USP7 6323.0
LSM10 6338.0
E2F1 6343.0
YWHAB 6385.0
CSNK2A2 6388.0
FOXO4 6391.0
CTNNB1 6408.0
RARA 6429.0
CITED2 6457.0
TP53INP1 6458.0
NDUFA4 6459.0
TAL1 6518.0
SREBF1 6539.0
PSMD12 6556.0
CLP1 6589.0
CPSF3 6602.0
EAF2 6605.0
COX8A 6611.0
CCNG2 6629.0
GSK3B 6634.0
PSMC6 6635.0
UBB 6639.0
PSMF1 6659.0
POLR2J 6671.0
PLK3 6680.0
ZNF230 6689.0
H3C15 6699.5
TWIST2 6721.0
MED20 6743.0
UBE2E1 6759.0
SATB2 6781.0
RRM2B 6798.0
CDC40 6801.0
JUNB 6806.0
PSMB6 6813.0
SUMO1 6889.0
ZNF710 6900.0
SMARCD2 6914.0
RMI1 6947.0
PSMC1 7021.0
PRDX1 7030.0
GTF2A2 7066.0
PSMA7 7096.0
PRKCB 7097.0
TAF10 7110.0
PAPOLA 7153.0
PSMB3 7171.0
ZNF267 7203.0
TAF13 7217.0
THOC5 7235.0
PSMD1 7241.0
ZNF143 7265.0
POLDIP3 7269.0
EIF4A3 7273.0
H2BC17 7285.0
ELOA 7312.0
PSMA1 7329.0
BCL2L11 7384.0
H2BC4 7389.0
PSMD2 7411.0
NR1H2 7415.0
SRSF9 7422.0
ZFHX3 7425.0
VEGFA 7467.0
ELOB 7482.0
SERPINE1 7483.0
CCND3 7487.0
MAPK1 7493.0
RXRA 7495.0
ELOC 7519.0
RUNX1 7529.0
MED8 7535.0
POLR2E 7563.0
LAMTOR2 7567.0
ZNF746 7573.0
LAMTOR3 7574.0
PSMD9 7620.0
NFYC 7653.0
ITGA5 7659.0
RHEB 7669.0
MYL9 7703.0
PPP2CB 7712.0
COX7A2L 7719.0
PPM1D 7810.0
MLLT1 7825.0
ELL2 7828.0
SMAD6 7835.0
CPSF2 7838.0
CITED4 7844.0
PSMD6 7846.0
NEDD4L 7875.0
TBL1X 7887.0
NOTCH3 7899.0
H2BC11 7912.0
H2AC6 7934.0
TNFRSF10C 7960.0
TOP3A 7973.0
TAF12 7977.0
NCOR2 7985.0
CEBPB 7997.0
NABP1 8001.0
H2BC5 8003.0
KMT5A 8005.0
NRBF2 8076.0
INTS8 8079.0
PSMB5 8101.0
LBR 8102.0
TXNRD1 8192.0
SP1 8193.0
PPM1A 8200.0
CNOT8 8227.0
PPP2CA 8234.0
PSME3 8251.0
TXN 8285.0
LMO2 8307.0
TNFRSF10B 8321.0
VDR 8348.0
PSMD4 8402.0
GATA1 8410.0
PTEN 8460.0
TFDP1 8470.0
PSMB7 8485.0
LAMTOR5 8498.0
SMAD1 8511.0
PRDX5 8531.0
NR6A1 8553.0
ARID3A 8584.0
CDK5 8616.0
UBE2D3 8640.0
YWHAH 8649.0
H3-3A 8661.0
SMARCD3 8668.0
FOXO3 8682.0
RB1 8707.0
JAG1 8743.0
LGALS3 8752.0
RRAGD 8753.0
RBPJ 8770.0
CDKN2B 8836.0
MAP2K6 8887.0
TGFA 8889.0
SPI1 8891.0
ITGA2B 8893.0
PINK1 8941.0
MAPK3 8953.0
MAML3 8957.0
HDAC4 8960.0
ANAPC15 8968.0
TP53I3 8979.0
RETN 8998.0
ZNF697 9002.0
G6PD 9004.0
APAF1 9015.0
CARM1 9020.0
SLC2A3 9021.0
PHC2 9043.0
YWHAE 9045.0
H2BC12 9051.0
AGO4 9070.0
TNFRSF10D 9072.0
GADD45A 9083.0
FKBP5 9091.0
MAPK14 9104.0
CAT 9123.0
BCL6 9175.0
UBE2D1 9187.0
GSR 9235.0
YWHAG 9264.0
H2BC21 9283.0
BNIP3L 9329.0
H2AJ 9374.0
NLRC4 9406.0
LAMTOR1 9411.0
PRKACA 9429.0
NFE2 9431.0
SOCS3 9476.0
CR1 9486.0
PPARG 9522.0


VEGFA-VEGFR2 Pathway

VEGFA-VEGFR2 Pathway
1307
set VEGFA-VEGFR2 Pathway
setSize 92
pANOVA 4.27e-07
s.dist 0.305
p.adjustANOVA 6.13e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
WASF1 9520
PRKACA 9429
CTNNA1 9341
NCF4 9268
CYFIP1 9265
NCF2 9190
MAPK14 9104
PIK3CB 9038
CYBB 9031
PRKCD 9008
CRK 8906
RAC1 8793
CDH5 8613
MAPKAPK3 8382
WASF2 8369
RHOA 8319
ITGB3 8291
PAK1 8230
PAK2 8185
PTK2B 7935

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
WASF1 9520
PRKACA 9429
CTNNA1 9341
NCF4 9268
CYFIP1 9265
NCF2 9190
MAPK14 9104
PIK3CB 9038
CYBB 9031
PRKCD 9008
CRK 8906
RAC1 8793
CDH5 8613
MAPKAPK3 8382
WASF2 8369
RHOA 8319
ITGB3 8291
PAK1 8230
PAK2 8185
PTK2B 7935
VAV1 7896
NCKAP1L 7673
SPHK1 7657
CDC42 7537
ROCK1 7489
VEGFA 7467
NCKAP1 7462
NCF1 7334
DOCK1 7314
PRKCB 7097
ABI1 7082
BRK1 7032
CYBA 6922
WASF3 6808
AHCYL1 6456
CTNNB1 6408
ELMO1 6258
PXN 6230
ROCK2 6138
PDPK1 6136
ITGAV 6106
SHB 6026
ITPR2 5842
NRAS 5363
MAPKAP1 5057
PIK3R2 5010
NCK2 4934
VAV3 4894
PIK3CA 4629
PTK2 4462
ELMO2 4397
SHC2 4183
MAPKAPK2 4054
MAPK13 3865
MAPK11 3826
KRAS 3702
AKT1 3614
RASA1 2106
CAV1 1969
HSPB1 1863
HSP90AA1 1326
PRKCA 1132
AKT2 433
MLST8 376
BAIAP2 -215
MAPK12 -1074
NOS3 -2059
CALM1 -2081
HRAS -3382
VAV2 -4055
PAK3 -4184
JUP -5353
TRIB3 -5843
ITPR1 -7629
CTNND1 -8403
SRC -8820
PIK3R1 -9505
RICTOR -9670
MTOR -9767
ITPR3 -10308
CYFIP2 -10367
ABI2 -10915
THEM4 -11069
PLCG1 -11120
NCK1 -11454
PRKCZ -11629
FYN -11675
AKT3 -11849
PRKACB -11959
PRR5 -11985
AXL -12331
SH2D2A -12359


MAP kinase activation

MAP kinase activation
610
set MAP kinase activation
setSize 63
pANOVA 4.52e-07
s.dist 0.367
p.adjustANOVA 6.43e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
DUSP3 9280
MAPK14 9104
MAP2K1 9063
MAPK3 8953
MAP2K6 8887
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PPP2CA 8234
MEF2A 8009
CHUK 7966
PPP2CB 7712
RPS6KA1 7695
MAPK1 7493
TAB2 6964
MAP2K4 6866
UBB 6639
NFKB1 6277
FBXW11 6196
MAP3K8 6160

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DUSP3 9280
MAPK14 9104
MAP2K1 9063
MAPK3 8953
MAP2K6 8887
MAP2K3 8748
NOD2 8442
MAPKAPK3 8382
PPP2CA 8234
MEF2A 8009
CHUK 7966
PPP2CB 7712
RPS6KA1 7695
MAPK1 7493
TAB2 6964
MAP2K4 6866
UBB 6639
NFKB1 6277
FBXW11 6196
MAP3K8 6160
IRAK1 6131
ATF1 5706
TAB1 5681
UBE2V1 5637
TNIP2 5552
FOS 5460
IKBKG 5377
PPP2R1A 4589
UBC 4439
DUSP6 4357
MAPK10 4325
SKP1 4287
MAPKAPK2 4054
MAPK11 3826
JUN 3722
TAB3 3160
RPS6KA2 3087
RPS6KA3 2973
PPP2R5D 2421
MAP3K7 2395
ATF2 2085
UBE2N 1936
MAP2K7 1654
VRK3 1281
UBA52 1121
ELK1 1040
RIPK2 1025
TRAF6 -229
PPP2R1B -241
MEF2C -293
MAPK7 -1337
CREB1 -1378
DUSP7 -3211
BTRC -4924
IKBKB -5386
DUSP4 -6287
RPS27A -6938
MAPK9 -7068
MAPK8 -9428
IRAK2 -9548
CUL1 -11330
RPS6KA5 -11594
NOD1 -12263


PIP3 activates AKT signaling

PIP3 activates AKT signaling
791
set PIP3 activates AKT signaling
setSize 241
pANOVA 6.02e-07
s.dist 0.187
p.adjustANOVA 8.46e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
PPARG 9522
LAMTOR1 9411
GRB2 9304
RCOR1 9073
AGO4 9070
PHC2 9043
PIK3CB 9038
VAPA 9033
KL 8963
MAPK3 8953
TGFA 8889
HGF 8863
MKRN1 8817
RAC1 8793
RRAGD 8753
RNF146 8696
FOXO3 8682
SNAI1 8645
IRS2 8569
LAMTOR5 8498

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PPARG 9522
LAMTOR1 9411
GRB2 9304
RCOR1 9073
AGO4 9070
PHC2 9043
PIK3CB 9038
VAPA 9033
KL 8963
MAPK3 8953
TGFA 8889
HGF 8863
MKRN1 8817
RAC1 8793
RRAGD 8753
RNF146 8696
FOXO3 8682
SNAI1 8645
IRS2 8569
LAMTOR5 8498
RHOG 8487
PSMB7 8485
PTEN 8460
PSMD4 8402
INSR 8282
PSME3 8251
PPP2CA 8234
EGF 8179
TRIM27 8142
MYD88 8136
PSMB5 8101
WWP2 8013
CHUK 7966
VAV1 7896
AKT1S1 7865
PSMD6 7846
PIK3AP1 7811
GSK3A 7760
PPP2CB 7712
CASP9 7685
RHEB 7669
PSMD9 7620
LAMTOR3 7574
LAMTOR2 7567
MAPK1 7493
IER3 7463
PSMD2 7411
PSMA1 7329
PSMD1 7241
PSMB3 7171
IL1RAP 7150
PSMA7 7096
PSMC1 7021
BAD 6892
PSMB6 6813
PPP2R5B 6774
PSMF1 6659
UBB 6639
PSMC6 6635
GSK3B 6634
PSMD12 6556
PIP5K1B 6450
FOXO4 6391
CSNK2A2 6388
USP7 6323
RRAGA 6244
PSMD11 6231
NEDD4 6201
CSNK2A1 6199
PDPK1 6136
IRAK1 6131
HDAC7 6122
PIP5K1A 6110
PIK3CD 6046
AREG 5977
PSMA6 5970
PSMD7 5963
PSMD13 5948
PPP2R5A 5897
PDGFRA 5858
PSMD8 5757
MAF1 5723
GAB1 5679
AGO1 5654
HDAC2 5482
CBX8 5448
PSMA2 5339
PTPN11 5314
PDGFA 5293
RAC2 5163
MAPKAP1 5057
HBEGF 5013
PIK3R2 5010
RRAGC 4954
HDAC5 4710
HDAC3 4673
PIK3CA 4629
PSMD3 4618
PPP2R1A 4589
CDKN1A 4511
LAMTOR4 4441
UBC 4439
SEM1 4348
MDM2 4312
PSMB2 4084
CBX6 4033
CSNK2B 3969
FGF2 3920
NRG1 3750
JUN 3722
STRN 3695
PHLPP1 3658
AKT1 3614
RNF2 3513
PSMD5 3426
PIP5K1C 3419
PSMB1 3374
IL1RL1 3175
EGR1 3124
GATAD2A 3075
AGO2 2995
SLC38A9 2807
EPGN 2662
PSMD14 2611
PSMC2 2598
PSMB4 2523
PPP2R5D 2421
CBX4 2222
ATF2 2085
PSMC3 1976
EREG 1888
IRS1 1741
MECOM 1687
PSMD10 1559
XIAP 1407
UBA52 1121
REST 865
RPS6KB2 700
HDAC1 587
IL33 445
AKT2 433
MLST8 376
ATN1 234
CD86 -14
FRK -24
TRAF6 -229
PPP2R1B -241
ERBB3 -472
TNKS2 -499
MBD3 -528
PSMA4 -616
PPP2R5E -680
RRAGB -713
TSC2 -804
PSMC5 -863
AGO3 -1011
STUB1 -1032
CREB1 -1378
GATAD2B -1759
RBBP4 -1870
NRG4 -1875
PIP4K2A -2365
SUZ12 -2409
MTA1 -3005
PSMB8 -3076
FGFR4 -3293
FRS2 -3433
CD19 -3843
RING1 -4063
FGF7 -4247
CHD4 -4515
TNRC6B -4518
CBX2 -4617
PTENP1 -5280
PSMA3 -5285
FGFR1 -5352
TNRC6A -5613
PSMB10 -5735
SCMH1 -5839
TRIB3 -5843
PSMA5 -6053
PSME4 -6087
SALL4 -6112
FOXO6 -6367
FGF23 -6622
USP13 -6737
NR4A1 -6756
CD80 -6841
RPS27A -6938
MTA2 -7317
TRAT1 -7535
PSMA8 -7606
PIP4K2B -7788
PHC3 -8152
CDKN1B -8207
PHC1 -8402
PDGFB -8577
FGF22 -8607
PML -8693
TNKS -8738
FGF9 -8761
SRC -8820
ESR1 -9122
PSMC4 -9127
ESR2 -9250
EED -9348
KDM1A -9430
MTA3 -9433
ICOS -9434
FOXO1 -9465
PIK3R1 -9505
RICTOR -9670
CHD3 -9737
EZH2 -9741
MTOR -9767
BMI1 -9829
PSME1 -9991
CD28 -10202
PSME2 -10336
MIR25 -10350
RPTOR -10464
OTUD3 -10763
TP53 -10893
KIT -11004
THEM4 -11069
CNOT6L -11248
PPP2R5C -11265
PSMB9 -11324
PIP4K2C -11371
PDGFRB -11545
FYN -11675
FGFR2 -11785
TNRC6C -11828
LCK -11838
AKT3 -11849
PHLPP2 -11948
PRR5 -11985
MOV10 -11991
PIK3R3 -12015
RBBP7 -12155
ERBB2 -12320


Toll Like Receptor 3 (TLR3) Cascade

Toll Like Receptor 3 (TLR3) Cascade
1238
set Toll Like Receptor 3 (TLR3) Cascade
setSize 92
pANOVA 6.7e-07
s.dist 0.3
p.adjustANOVA 9.33e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
DUSP3 9280
UBE2D1 9187
APP 9177
MAPK14 9104
MAP2K1 9063
MAPK3 8953
MAP2K6 8887
MAP2K3 8748
UBE2D3 8640
NOD2 8442
MAPKAPK3 8382
PPP2CA 8234
MEF2A 8009
CHUK 7966
PPP2CB 7712
RPS6KA1 7695
TANK 7502
MAPK1 7493

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A12 9515
NKIRAS2 9353
DUSP3 9280
UBE2D1 9187
APP 9177
MAPK14 9104
MAP2K1 9063
MAPK3 8953
MAP2K6 8887
MAP2K3 8748
UBE2D3 8640
NOD2 8442
MAPKAPK3 8382
PPP2CA 8234
MEF2A 8009
CHUK 7966
PPP2CB 7712
RPS6KA1 7695
TANK 7502
MAPK1 7493
TAB2 6964
MAP2K4 6866
NFKBIA 6807
UBB 6639
TICAM1 6307
NFKB1 6277
FBXW11 6196
MAP3K8 6160
IRAK1 6131
ATF1 5706
TAB1 5681
FADD 5641
UBE2V1 5637
TNIP2 5552
FOS 5460
IKBKG 5377
IKBKE 4715
BIRC2 4692
UBE2D2 4657
PPP2R1A 4589
UBC 4439
DUSP6 4357
MAPK10 4325
SKP1 4287
RIPK3 4217
MAPKAPK2 4054
MAPK11 3826
JUN 3722
TBK1 3229
TAB3 3160
RPS6KA2 3087
RPS6KA3 2973
PPP2R5D 2421
MAP3K7 2395
ATF2 2085
UBE2N 1936
MAP2K7 1654
AGER 1294
VRK3 1281
UBA52 1121
ELK1 1040
RIPK2 1025
NKIRAS1 375
NFKBIB -152
TRAF6 -229
PPP2R1B -241
HMGB1 -252
MEF2C -293
NFKB2 -1165
MAPK7 -1337
CREB1 -1378
RELA -1803
DUSP7 -3211
BTRC -4924
IKBKB -5386
S100B -5457
TRAF3 -5576
DUSP4 -6287
RPS27A -6938
MAPK9 -7068
IRF3 -8517
IRF7 -8657
MAPK8 -9428
IRAK2 -9548
RIPK1 -11074
BIRC3 -11125
CUL1 -11330
CASP8 -11336
TLR3 -11525
RPS6KA5 -11594
SARM1 -12134
NOD1 -12263


Signaling by NOTCH4

Signaling by NOTCH4
1116
set Signaling by NOTCH4
setSize 79
pANOVA 6.95e-07
s.dist 0.323
p.adjustANOVA 9.57e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
TACC3 9331
NCSTN 9186
MAML3 8957
ADAM10 8791
RBPJ 8770
JAG1 8743
PSMB7 8485
PSMD4 8402
PSME3 8251
PSMB5 8101
PSEN1 7961
PSMD6 7846
PSMD9 7620
PSMD2 7411
PSMA1 7329
PSMD1 7241
PSMB3 7171
PSMA7 7096
PSMC1 7021
PSMB6 6813

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TACC3 9331
NCSTN 9186
MAML3 8957
ADAM10 8791
RBPJ 8770
JAG1 8743
PSMB7 8485
PSMD4 8402
PSME3 8251
PSMB5 8101
PSEN1 7961
PSMD6 7846
PSMD9 7620
PSMD2 7411
PSMA1 7329
PSMD1 7241
PSMB3 7171
PSMA7 7096
PSMC1 7021
PSMB6 6813
PSMF1 6659
UBB 6639
PSMC6 6635
PSMD12 6556
APH1B 6280
PSMD11 6231
EP300 6129
PSMA6 5970
PSMD7 5963
PSMD13 5948
PSMD8 5757
PSENEN 5735
YWHAZ 5624
MAML1 5404
PSMA2 5339
NOTCH2 5272
SNW1 5201
NOTCH1 4704
PSMD3 4618
UBC 4439
SEM1 4348
SKP1 4287
APH1A 4133
PSMB2 4084
RBX1 3934
AKT1 3614
PSMD5 3426
CREBBP 3423
PSMB1 3374
PSMD14 2611
PSMC2 2598
PSMB4 2523
PSMC3 1976
PSMD10 1559
UBA52 1121
ACTA2 -429
MAML2 -582
PSMA4 -616
PSMC5 -863
KAT2B -2414
PSMB8 -3076
NOTCH4 -5229
PSMA3 -5285
MAMLD1 -5584
PSMB10 -5735
PSMA5 -6053
FBXW7 -6600
RPS27A -6938
FLT4 -7216
PSEN2 -7718
HES1 -8266
PSMC4 -9127
HEY2 -9752
PSME1 -9991
PSME2 -10336
KAT2A -10771
PSMB9 -11324
CUL1 -11330
SMAD3 -11745


Signaling by MET

Signaling by MET
1106
set Signaling by MET
setSize 61
pANOVA 7.13e-07
s.dist 0.367
p.adjustANOVA 9.72e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
LAMC1 9387
GRB2 9304
TNS3 9262
CRK 8906
HGF 8863
RAC1 8793
SPINT1 8446
SPINT2 8206
STAT3 8098
RAB4A 7941
PTPRJ 7783
SH3GL1 7625
PTPN2 7615
LAMB3 7497
CBL 7480
RAP1A 7305
UBB 6639
USP8 6418
SH3KBP1 6173
STAM2 6159

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
LAMC1 9387
GRB2 9304
TNS3 9262
CRK 8906
HGF 8863
RAC1 8793
SPINT1 8446
SPINT2 8206
STAT3 8098
RAB4A 7941
PTPRJ 7783
SH3GL1 7625
PTPN2 7615
LAMB3 7497
CBL 7480
RAP1A 7305
UBB 6639
USP8 6418
SH3KBP1 6173
STAM2 6159
LAMB1 5966
RANBP9 5813
PTPN1 5722
GAB1 5679
NRAS 5363
PTPN11 5314
PIK3CA 4629
HGS 4513
PTK2 4462
UBC 4439
ITGA2 4168
SHC1 4161
EPS15 4138
CRKL 3966
GGA3 3816
KRAS 3702
RAP1B 3206
RAB4B 3137
HPN 2625
RANBP10 2553
ARF6 1377
STAM 1285
UBA52 1121
LAMB2 501
TNS4 100
ITGB1 -94
LAMA1 -1044
LAMC3 -2016
LAMA4 -2252
DOCK7 -2369
LAMA5 -3263
HRAS -3382
SOS1 -5700
MUC20 -5962
RPS27A -6938
SRC -8820
PIK3R1 -9505
RAPGEF1 -9826
LAMA2 -9911
LRIG1 -10389
ITGA3 -10750


Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.0.2 (2020-06-22)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 18.04.5 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.7.1
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.7.1
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.1.0               GGally_2.0.0               
##  [3] beeswarm_0.2.3              gtools_3.8.2               
##  [5] echarts4r_0.3.2             mitch_1.0.6                
##  [7] MASS_7.3-52                 fgsea_1.14.0               
##  [9] gplots_3.0.3                DESeq2_1.28.1              
## [11] SummarizedExperiment_1.18.1 DelayedArray_0.14.0        
## [13] matrixStats_0.56.0          Biobase_2.48.0             
## [15] GenomicRanges_1.40.0        GenomeInfoDb_1.24.2        
## [17] IRanges_2.22.2              S4Vectors_0.26.1           
## [19] BiocGenerics_0.34.0         reshape2_1.4.4             
## [21] forcats_0.5.0               stringr_1.4.0              
## [23] dplyr_1.0.0                 purrr_0.3.4                
## [25] readr_1.3.1                 tidyr_1.1.0                
## [27] tibble_3.0.1                ggplot2_3.3.2              
## [29] tidyverse_1.3.0            
## 
## loaded via a namespace (and not attached):
##  [1] colorspace_1.4-1       ellipsis_0.3.1         rprojroot_1.3-2       
##  [4] XVector_0.28.0         fs_1.4.2               rstudioapi_0.11       
##  [7] bit64_0.9-7            AnnotationDbi_1.50.1   fansi_0.4.1           
## [10] lubridate_1.7.9        xml2_1.3.2             splines_4.0.2         
## [13] geneplotter_1.66.0     knitr_1.29             jsonlite_1.7.0        
## [16] broom_0.5.6            annotate_1.66.0        dbplyr_1.4.4          
## [19] shiny_1.5.0            compiler_4.0.2         httr_1.4.1            
## [22] backports_1.1.8        assertthat_0.2.1       Matrix_1.2-18         
## [25] fastmap_1.0.1          cli_2.0.2              later_1.1.0.1         
## [28] htmltools_0.5.0        tools_4.0.2            gtable_0.3.0          
## [31] glue_1.4.1             GenomeInfoDbData_1.2.3 fastmatch_1.1-0       
## [34] Rcpp_1.0.4.6           cellranger_1.1.0       vctrs_0.3.1           
## [37] gdata_2.18.0           nlme_3.1-148           xfun_0.15             
## [40] testthat_2.3.2         rvest_0.3.5            mime_0.9              
## [43] lifecycle_0.2.0        XML_3.99-0.3           zlibbioc_1.34.0       
## [46] scales_1.1.1           hms_0.5.3              promises_1.1.1        
## [49] RColorBrewer_1.1-2     yaml_2.2.1             memoise_1.1.0         
## [52] gridExtra_2.3          reshape_0.8.8          stringi_1.4.6         
## [55] RSQLite_2.2.0          highr_0.8              genefilter_1.70.0     
## [58] desc_1.2.0             caTools_1.18.0         BiocParallel_1.22.0   
## [61] rlang_0.4.6            pkgconfig_2.0.3        bitops_1.0-6          
## [64] evaluate_0.14          lattice_0.20-41        htmlwidgets_1.5.1     
## [67] bit_1.1-15.2           tidyselect_1.1.0       plyr_1.8.6            
## [70] magrittr_1.5           R6_2.4.1               generics_0.0.2        
## [73] DBI_1.1.0              pillar_1.4.4           haven_2.3.1           
## [76] withr_2.2.0            survival_3.2-3         RCurl_1.98-1.2        
## [79] modelr_0.1.8           crayon_1.3.4           KernSmooth_2.23-17    
## [82] rmarkdown_2.3          locfit_1.5-9.4         grid_4.0.2            
## [85] readxl_1.3.1           data.table_1.12.8      blob_1.2.1            
## [88] reprex_0.3.0           digest_0.6.25          pbmcapply_1.5.0       
## [91] xtable_1.8-4           httpuv_1.5.4           munsell_0.5.0

END of report