Mitch Report
Antony Kaspi & Mark Ziemann
date generated: 2022-01-20
Background
Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch
Input profiles
Here is the first few lines of the input profile.
## x
## A1BG 4.1644895
## A1CF 2.8783151
## A2M 0.3828562
## A4GALT 1.0571952
## AAAS 1.0071471
## AACS 2.0539621| Profile metrics | |
|---|---|
| num_genesets | 2512 |
| num_genes_in_profile | 14533 |
| duplicated_genes_present | 0 |
| num_profile_genes_in_sets | 7596 |
| num_profile_genes_not_in_sets | 6937 |
Here is a plot of the input profiles. Note the dynamic ranges. 
Here is the contour plot of the profile including all detected genes.
Input genesets
Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt| Gene sets metrics | |
|---|---|
| num_genesets | 2512 |
| num_genesets_excluded | 1135 |
| num_genesets_included | 1377 |
Differential pathway expression
Interactive enrichment scatterplot
Significance is calculated by -log10(p-value). All points shown are FDR<0.05.
Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.
Results table
Top N= 50 gene sets| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| Unfolded Protein Response (UPR) | 89 | 9.26e-10 | 0.3760 | 1.27e-06 |
| Asparagine N-linked glycosylation | 252 | 7.65e-09 | 0.2120 | 5.12e-06 |
| IRE1alpha activates chaperones | 50 | 1.48e-08 | 0.4630 | 5.12e-06 |
| Innate Immune System | 740 | 1.49e-08 | 0.1230 | 5.12e-06 |
| Cholesterol biosynthesis | 24 | 2.32e-08 | 0.6590 | 6.40e-06 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | 54 | 5.07e-08 | 0.4290 | 1.16e-05 |
| XBP1(S) activates chaperone genes | 48 | 1.21e-07 | 0.4420 | 2.21e-05 |
| Signal Transduction | 1748 | 1.28e-07 | 0.0777 | 2.21e-05 |
| Metabolism | 1696 | 1.50e-07 | 0.0783 | 2.29e-05 |
| Immune System | 1374 | 1.75e-07 | 0.0855 | 2.41e-05 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | 99 | 5.59e-07 | 0.2910 | 7.00e-05 |
| Complement cascade | 35 | 6.84e-07 | 0.4850 | 7.85e-05 |
| Post-translational protein phosphorylation | 91 | 1.12e-06 | 0.2960 | 1.18e-04 |
| Post-translational protein modification | 1138 | 4.03e-06 | 0.0822 | 3.96e-04 |
| Initial triggering of complement | 12 | 4.38e-06 | 0.7650 | 4.02e-04 |
| Metabolism of lipids | 592 | 7.79e-06 | 0.1080 | 6.70e-04 |
| Platelet degranulation | 103 | 1.12e-05 | 0.2510 | 8.88e-04 |
| Activation of gene expression by SREBF (SREBP) | 42 | 1.16e-05 | 0.3910 | 8.88e-04 |
| Transport of small molecules | 535 | 1.35e-05 | 0.1110 | 9.80e-04 |
| Regulation of Complement cascade | 30 | 1.50e-05 | 0.4570 | 1.03e-03 |
| Hemostasis | 409 | 2.39e-05 | 0.1220 | 1.54e-03 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | 34 | 2.46e-05 | 0.4180 | 1.54e-03 |
| Neutrophil degranulation | 352 | 3.51e-05 | 0.1290 | 2.10e-03 |
| Response to elevated platelet cytosolic Ca2+ | 106 | 3.66e-05 | 0.2320 | 2.10e-03 |
| Transferrin endocytosis and recycling | 29 | 5.72e-05 | 0.4320 | 3.08e-03 |
| DNA strand elongation | 32 | 5.82e-05 | 0.4110 | 3.08e-03 |
| Cellular responses to stimuli | 641 | 7.93e-05 | 0.0920 | 4.04e-03 |
| Collagen degradation | 20 | 9.85e-05 | 0.5030 | 4.82e-03 |
| Signaling by Rho GTPases, Miro GTPases and RHOBTB3 | 566 | 1.02e-04 | 0.0962 | 4.82e-03 |
| Cellular responses to stress | 633 | 1.29e-04 | 0.0898 | 5.94e-03 |
| Apoptotic execution phase | 39 | 1.39e-04 | 0.3530 | 6.16e-03 |
| Signaling by Rho GTPases | 551 | 1.57e-04 | 0.0947 | 6.78e-03 |
| Plasma lipoprotein remodeling | 29 | 1.74e-04 | 0.4030 | 7.28e-03 |
| Metabolism of steroids | 130 | 2.40e-04 | 0.1870 | 9.73e-03 |
| Platelet activation, signaling and aggregation | 189 | 2.51e-04 | 0.1550 | 9.89e-03 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | 64 | 3.04e-04 | 0.2610 | 1.16e-02 |
| Metabolism of proteins | 1550 | 3.40e-04 | 0.0556 | 1.26e-02 |
| Calnexin/calreticulin cycle | 25 | 3.69e-04 | 0.4120 | 1.31e-02 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | 31 | 3.70e-04 | 0.3700 | 1.31e-02 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | 34 | 4.08e-04 | 0.3500 | 1.40e-02 |
| Cell Cycle, Mitotic | 478 | 5.90e-04 | 0.0923 | 1.97e-02 |
| Synthesis of substrates in N-glycan biosythesis | 49 | 6.01e-04 | 0.2830 | 1.97e-02 |
| Interleukin-12 signaling | 38 | 7.67e-04 | 0.3150 | 2.37e-02 |
| NOTCH4 Intracellular Domain Regulates Transcription | 15 | 7.77e-04 | 0.5010 | 2.37e-02 |
| Signaling by Interleukins | 315 | 7.88e-04 | 0.1100 | 2.37e-02 |
| Cell Cycle | 594 | 7.91e-04 | 0.0812 | 2.37e-02 |
| RHO GTPases Activate Formins | 116 | 1.07e-03 | 0.1760 | 3.13e-02 |
| Inactivation, recovery and regulation of the phototransduction cascade | 20 | 1.11e-03 | -0.4210 | 3.17e-02 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | 90 | 1.24e-03 | 0.1970 | 3.41e-02 |
| Amplification of signal from the kinetochores | 90 | 1.24e-03 | 0.1970 | 3.41e-02 |
Results (complete table)
Click HERE to show results for all gene sets
| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| Unfolded Protein Response (UPR) | 89 | 9.26e-10 | 3.76e-01 | 1.27e-06 |
| Asparagine N-linked glycosylation | 252 | 7.65e-09 | 2.12e-01 | 5.12e-06 |
| IRE1alpha activates chaperones | 50 | 1.48e-08 | 4.63e-01 | 5.12e-06 |
| Innate Immune System | 740 | 1.49e-08 | 1.23e-01 | 5.12e-06 |
| Cholesterol biosynthesis | 24 | 2.32e-08 | 6.59e-01 | 6.40e-06 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | 54 | 5.07e-08 | 4.29e-01 | 1.16e-05 |
| XBP1(S) activates chaperone genes | 48 | 1.21e-07 | 4.42e-01 | 2.21e-05 |
| Signal Transduction | 1748 | 1.28e-07 | 7.77e-02 | 2.21e-05 |
| Metabolism | 1696 | 1.50e-07 | 7.83e-02 | 2.29e-05 |
| Immune System | 1374 | 1.75e-07 | 8.55e-02 | 2.41e-05 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | 99 | 5.59e-07 | 2.91e-01 | 7.00e-05 |
| Complement cascade | 35 | 6.84e-07 | 4.85e-01 | 7.85e-05 |
| Post-translational protein phosphorylation | 91 | 1.12e-06 | 2.96e-01 | 1.18e-04 |
| Post-translational protein modification | 1138 | 4.03e-06 | 8.22e-02 | 3.96e-04 |
| Initial triggering of complement | 12 | 4.38e-06 | 7.65e-01 | 4.02e-04 |
| Metabolism of lipids | 592 | 7.79e-06 | 1.08e-01 | 6.70e-04 |
| Platelet degranulation | 103 | 1.12e-05 | 2.51e-01 | 8.88e-04 |
| Activation of gene expression by SREBF (SREBP) | 42 | 1.16e-05 | 3.91e-01 | 8.88e-04 |
| Transport of small molecules | 535 | 1.35e-05 | 1.11e-01 | 9.80e-04 |
| Regulation of Complement cascade | 30 | 1.50e-05 | 4.57e-01 | 1.03e-03 |
| Hemostasis | 409 | 2.39e-05 | 1.22e-01 | 1.54e-03 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | 34 | 2.46e-05 | 4.18e-01 | 1.54e-03 |
| Neutrophil degranulation | 352 | 3.51e-05 | 1.29e-01 | 2.10e-03 |
| Response to elevated platelet cytosolic Ca2+ | 106 | 3.66e-05 | 2.32e-01 | 2.10e-03 |
| Transferrin endocytosis and recycling | 29 | 5.72e-05 | 4.32e-01 | 3.08e-03 |
| DNA strand elongation | 32 | 5.82e-05 | 4.11e-01 | 3.08e-03 |
| Cellular responses to stimuli | 641 | 7.93e-05 | 9.20e-02 | 4.04e-03 |
| Collagen degradation | 20 | 9.85e-05 | 5.03e-01 | 4.82e-03 |
| Signaling by Rho GTPases, Miro GTPases and RHOBTB3 | 566 | 1.02e-04 | 9.62e-02 | 4.82e-03 |
| Cellular responses to stress | 633 | 1.29e-04 | 8.98e-02 | 5.94e-03 |
| Apoptotic execution phase | 39 | 1.39e-04 | 3.53e-01 | 6.16e-03 |
| Signaling by Rho GTPases | 551 | 1.57e-04 | 9.47e-02 | 6.78e-03 |
| Plasma lipoprotein remodeling | 29 | 1.74e-04 | 4.03e-01 | 7.28e-03 |
| Metabolism of steroids | 130 | 2.40e-04 | 1.87e-01 | 9.73e-03 |
| Platelet activation, signaling and aggregation | 189 | 2.51e-04 | 1.55e-01 | 9.89e-03 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | 64 | 3.04e-04 | 2.61e-01 | 1.16e-02 |
| Metabolism of proteins | 1550 | 3.40e-04 | 5.56e-02 | 1.26e-02 |
| Calnexin/calreticulin cycle | 25 | 3.69e-04 | 4.12e-01 | 1.31e-02 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | 31 | 3.70e-04 | 3.70e-01 | 1.31e-02 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | 34 | 4.08e-04 | 3.50e-01 | 1.40e-02 |
| Cell Cycle, Mitotic | 478 | 5.90e-04 | 9.23e-02 | 1.97e-02 |
| Synthesis of substrates in N-glycan biosythesis | 49 | 6.01e-04 | 2.83e-01 | 1.97e-02 |
| Interleukin-12 signaling | 38 | 7.67e-04 | 3.15e-01 | 2.37e-02 |
| NOTCH4 Intracellular Domain Regulates Transcription | 15 | 7.77e-04 | 5.01e-01 | 2.37e-02 |
| Signaling by Interleukins | 315 | 7.88e-04 | 1.10e-01 | 2.37e-02 |
| Cell Cycle | 594 | 7.91e-04 | 8.12e-02 | 2.37e-02 |
| RHO GTPases Activate Formins | 116 | 1.07e-03 | 1.76e-01 | 3.13e-02 |
| Inactivation, recovery and regulation of the phototransduction cascade | 20 | 1.11e-03 | -4.21e-01 | 3.17e-02 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | 90 | 1.24e-03 | 1.97e-01 | 3.41e-02 |
| Amplification of signal from the kinetochores | 90 | 1.24e-03 | 1.97e-01 | 3.41e-02 |
| Disease | 1247 | 1.30e-03 | 5.50e-02 | 3.50e-02 |
| EML4 and NUDC in mitotic spindle formation | 94 | 1.37e-03 | 1.91e-01 | 3.64e-02 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | 19 | 1.70e-03 | 4.16e-01 | 4.41e-02 |
| Interleukin-12 family signaling | 46 | 1.90e-03 | 2.65e-01 | 4.79e-02 |
| Fatty acid metabolism | 130 | 1.91e-03 | 1.58e-01 | 4.79e-02 |
| Iron uptake and transport | 55 | 1.99e-03 | 2.41e-01 | 4.89e-02 |
| Response of EIF2AK1 (HRI) to heme deficiency | 15 | 2.13e-03 | 4.58e-01 | 5.16e-02 |
| The phototransduction cascade | 21 | 2.30e-03 | -3.84e-01 | 5.46e-02 |
| ATF6 (ATF6-alpha) activates chaperones | 12 | 2.46e-03 | 5.05e-01 | 5.58e-02 |
| Unwinding of DNA | 12 | 2.48e-03 | 5.05e-01 | 5.58e-02 |
| Regulation of lipid metabolism by PPARalpha | 115 | 2.51e-03 | 1.63e-01 | 5.58e-02 |
| COPI-dependent Golgi-to-ER retrograde traffic | 75 | 2.52e-03 | 2.02e-01 | 5.58e-02 |
| ABC transporter disorders | 70 | 2.55e-03 | 2.09e-01 | 5.58e-02 |
| Initiation of Nuclear Envelope (NE) Reformation | 19 | 2.60e-03 | 3.99e-01 | 5.59e-02 |
| Disorders of transmembrane transporters | 140 | 2.75e-03 | 1.47e-01 | 5.83e-02 |
| PKA-mediated phosphorylation of CREB | 14 | 3.10e-03 | -4.57e-01 | 6.47e-02 |
| Pre-NOTCH Expression and Processing | 46 | 3.17e-03 | 2.52e-01 | 6.52e-02 |
| ATF6 (ATF6-alpha) activates chaperone genes | 10 | 3.30e-03 | 5.37e-01 | 6.67e-02 |
| PPARA activates gene expression | 113 | 3.44e-03 | 1.59e-01 | 6.87e-02 |
| TP53 Regulates Transcription of Cell Death Genes | 41 | 3.68e-03 | 2.62e-01 | 7.23e-02 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | 12 | 3.78e-03 | 4.83e-01 | 7.23e-02 |
| alpha-linolenic acid (ALA) metabolism | 12 | 3.78e-03 | 4.83e-01 | 7.23e-02 |
| Regulation of HSF1-mediated heat shock response | 74 | 3.87e-03 | 1.94e-01 | 7.31e-02 |
| SARS-CoV-2 Infection | 69 | 4.08e-03 | 2.00e-01 | 7.58e-02 |
| Sialic acid metabolism | 22 | 4.19e-03 | 3.53e-01 | 7.69e-02 |
| RHO GTPase Effectors | 222 | 4.39e-03 | 1.11e-01 | 7.86e-02 |
| Cell Cycle Checkpoints | 249 | 4.40e-03 | 1.05e-01 | 7.86e-02 |
| Olfactory Signaling Pathway | 14 | 4.51e-03 | -4.38e-01 | 7.97e-02 |
| Insulin receptor recycling | 23 | 5.07e-03 | 3.38e-01 | 8.83e-02 |
| Degradation of the extracellular matrix | 61 | 5.27e-03 | 2.07e-01 | 9.08e-02 |
| Glycosphingolipid metabolism | 39 | 6.08e-03 | 2.54e-01 | 1.01e-01 |
| RUNX3 regulates NOTCH signaling | 12 | 6.18e-03 | 4.56e-01 | 1.01e-01 |
| Lagging Strand Synthesis | 20 | 6.19e-03 | 3.54e-01 | 1.01e-01 |
| Cellular response to heat stress | 91 | 6.21e-03 | 1.66e-01 | 1.01e-01 |
| Dissolution of Fibrin Clot | 12 | 6.22e-03 | 4.56e-01 | 1.01e-01 |
| Signaling by Receptor Tyrosine Kinases | 405 | 6.32e-03 | 7.95e-02 | 1.01e-01 |
| Mitotic Spindle Checkpoint | 107 | 6.40e-03 | 1.53e-01 | 1.01e-01 |
| MHC class II antigen presentation | 84 | 6.52e-03 | 1.72e-01 | 1.02e-01 |
| DNA Replication | 127 | 6.66e-03 | 1.40e-01 | 1.03e-01 |
| Activation of NMDA receptors and postsynaptic events | 56 | 6.82e-03 | -2.09e-01 | 1.04e-01 |
| Transport to the Golgi and subsequent modification | 146 | 7.21e-03 | 1.29e-01 | 1.09e-01 |
| Resolution of Sister Chromatid Cohesion | 103 | 7.34e-03 | 1.53e-01 | 1.09e-01 |
| Termination of translesion DNA synthesis | 32 | 7.57e-03 | 2.73e-01 | 1.09e-01 |
| Activation of the pre-replicative complex | 32 | 7.58e-03 | 2.73e-01 | 1.09e-01 |
| RHO GTPase cycle | 387 | 7.64e-03 | 7.94e-02 | 1.09e-01 |
| Biological oxidations | 155 | 7.66e-03 | 1.24e-01 | 1.09e-01 |
| DNA Replication Pre-Initiation | 85 | 7.75e-03 | 1.67e-01 | 1.09e-01 |
| Amino acid transport across the plasma membrane | 28 | 7.75e-03 | 2.91e-01 | 1.09e-01 |
| RHOQ GTPase cycle | 54 | 7.81e-03 | 2.09e-01 | 1.09e-01 |
| Neurotransmitter receptors and postsynaptic signal transmission | 108 | 8.03e-03 | -1.48e-01 | 1.09e-01 |
| Mitotic Anaphase | 221 | 8.05e-03 | 1.04e-01 | 1.09e-01 |
| ER Quality Control Compartment (ERQC) | 20 | 8.10e-03 | 3.42e-01 | 1.09e-01 |
| Mitotic Metaphase and Anaphase | 222 | 8.38e-03 | 1.03e-01 | 1.09e-01 |
| Mitotic Prophase | 81 | 8.38e-03 | 1.70e-01 | 1.09e-01 |
| Interconversion of nucleotide di- and triphosphates | 27 | 8.40e-03 | 2.93e-01 | 1.09e-01 |
| Apoptotic cleavage of cellular proteins | 31 | 8.43e-03 | 2.73e-01 | 1.09e-01 |
| Telomere C-strand (Lagging Strand) Synthesis | 34 | 8.66e-03 | 2.60e-01 | 1.12e-01 |
| Processive synthesis on the lagging strand | 15 | 8.93e-03 | 3.90e-01 | 1.14e-01 |
| M Phase | 339 | 9.32e-03 | 8.25e-02 | 1.16e-01 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | 26 | 9.45e-03 | 2.94e-01 | 1.16e-01 |
| Phase II - Conjugation of compounds | 75 | 9.49e-03 | 1.73e-01 | 1.16e-01 |
| Plasma lipoprotein assembly, remodeling, and clearance | 64 | 9.50e-03 | 1.88e-01 | 1.16e-01 |
| Ethanol oxidation | 10 | 9.53e-03 | 4.73e-01 | 1.16e-01 |
| TNFs bind their physiological receptors | 11 | 1.05e-02 | -4.46e-01 | 1.27e-01 |
| RHOF GTPase cycle | 40 | 1.06e-02 | 2.34e-01 | 1.27e-01 |
| Telomere C-strand synthesis initiation | 13 | 1.07e-02 | 4.09e-01 | 1.27e-01 |
| Homologous DNA Pairing and Strand Exchange | 42 | 1.09e-02 | 2.27e-01 | 1.29e-01 |
| Leading Strand Synthesis | 14 | 1.11e-02 | 3.92e-01 | 1.29e-01 |
| Polymerase switching | 14 | 1.11e-02 | 3.92e-01 | 1.29e-01 |
| Glutamate and glutamine metabolism | 11 | 1.20e-02 | 4.37e-01 | 1.38e-01 |
| Response of Mtb to phagocytosis | 21 | 1.28e-02 | 3.14e-01 | 1.46e-01 |
| SLC-mediated transmembrane transport | 174 | 1.35e-02 | 1.09e-01 | 1.52e-01 |
| NOTCH3 Intracellular Domain Regulates Transcription | 17 | 1.36e-02 | 3.46e-01 | 1.52e-01 |
| LDL clearance | 19 | 1.38e-02 | 3.26e-01 | 1.52e-01 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | 18 | 1.39e-02 | 3.35e-01 | 1.52e-01 |
| Formation of a pool of free 40S subunits | 98 | 1.39e-02 | -1.44e-01 | 1.52e-01 |
| Advanced glycosylation endproduct receptor signaling | 10 | 1.41e-02 | 4.48e-01 | 1.53e-01 |
| ER to Golgi Anterograde Transport | 122 | 1.46e-02 | 1.28e-01 | 1.57e-01 |
| HDR through Homologous Recombination (HRR) | 66 | 1.48e-02 | 1.74e-01 | 1.58e-01 |
| Common Pathway of Fibrin Clot Formation | 16 | 1.53e-02 | 3.50e-01 | 1.62e-01 |
| Cytokine Signaling in Immune system | 492 | 1.55e-02 | 6.41e-02 | 1.63e-01 |
| Removal of the Flap Intermediate | 14 | 1.57e-02 | 3.73e-01 | 1.63e-01 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | 38 | 1.60e-02 | 2.26e-01 | 1.65e-01 |
| FCGR3A-mediated IL10 synthesis | 23 | 1.60e-02 | -2.90e-01 | 1.65e-01 |
| Cell-extracellular matrix interactions | 14 | 1.65e-02 | 3.70e-01 | 1.68e-01 |
| Gap junction trafficking and regulation | 14 | 1.66e-02 | 3.70e-01 | 1.68e-01 |
| ABC-family proteins mediated transport | 92 | 1.70e-02 | 1.44e-01 | 1.71e-01 |
| Signaling by PDGF | 44 | 1.72e-02 | 2.08e-01 | 1.71e-01 |
| Assembly of active LPL and LIPC lipase complexes | 16 | 1.77e-02 | 3.42e-01 | 1.74e-01 |
| MyD88 deficiency (TLR2/4) | 11 | 1.78e-02 | 4.13e-01 | 1.74e-01 |
| Gap junction trafficking | 12 | 1.78e-02 | 3.95e-01 | 1.74e-01 |
| Integrin cell surface interactions | 45 | 1.80e-02 | 2.04e-01 | 1.75e-01 |
| Selenocysteine synthesis | 89 | 1.89e-02 | -1.44e-01 | 1.77e-01 |
| Regulation of PTEN mRNA translation | 12 | 1.89e-02 | 3.91e-01 | 1.77e-01 |
| Defective CFTR causes cystic fibrosis | 56 | 1.90e-02 | 1.81e-01 | 1.77e-01 |
| Hedgehog ligand biogenesis | 59 | 1.91e-02 | 1.76e-01 | 1.77e-01 |
| Polymerase switching on the C-strand of the telomere | 26 | 1.95e-02 | 2.65e-01 | 1.77e-01 |
| PKA activation | 12 | 1.95e-02 | -3.89e-01 | 1.77e-01 |
| Infection with Mycobacterium tuberculosis | 22 | 1.98e-02 | 2.87e-01 | 1.77e-01 |
| Defective HDR through Homologous Recombination (HRR) due to BRCA1 loss-of-function | 24 | 1.99e-02 | 2.75e-01 | 1.77e-01 |
| Defective HDR through Homologous Recombination (HRR) due to PALB2 loss of function | 24 | 1.99e-02 | 2.75e-01 | 1.77e-01 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | 24 | 1.99e-02 | 2.75e-01 | 1.77e-01 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | 24 | 1.99e-02 | 2.75e-01 | 1.77e-01 |
| Diseases of DNA Double-Strand Break Repair | 24 | 1.99e-02 | 2.75e-01 | 1.77e-01 |
| PKA activation in glucagon signalling | 11 | 2.00e-02 | -4.05e-01 | 1.77e-01 |
| Separation of Sister Chromatids | 165 | 2.08e-02 | 1.04e-01 | 1.84e-01 |
| Eukaryotic Translation Elongation | 91 | 2.12e-02 | -1.40e-01 | 1.86e-01 |
| Collagen biosynthesis and modifying enzymes | 36 | 2.14e-02 | 2.22e-01 | 1.86e-01 |
| SUMOylation of transcription factors | 16 | 2.15e-02 | -3.32e-01 | 1.86e-01 |
| Peptide chain elongation | 86 | 2.19e-02 | -1.43e-01 | 1.89e-01 |
| RHOJ GTPase cycle | 49 | 2.22e-02 | 1.89e-01 | 1.89e-01 |
| Regulation of TLR by endogenous ligand | 12 | 2.23e-02 | 3.81e-01 | 1.89e-01 |
| Cohesin Loading onto Chromatin | 10 | 2.24e-02 | -4.17e-01 | 1.89e-01 |
| Metabolism of carbohydrates | 235 | 2.26e-02 | 8.66e-02 | 1.90e-01 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | 95 | 2.28e-02 | 1.35e-01 | 1.90e-01 |
| RND2 GTPase cycle | 37 | 2.36e-02 | 2.15e-01 | 1.96e-01 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | 11 | 2.43e-02 | 3.92e-01 | 2.00e-01 |
| Binding and Uptake of Ligands by Scavenger Receptors | 27 | 2.46e-02 | 2.50e-01 | 2.02e-01 |
| DNA Damage Bypass | 47 | 2.51e-02 | 1.89e-01 | 2.04e-01 |
| Kinesins | 37 | 2.52e-02 | 2.13e-01 | 2.04e-01 |
| Homology Directed Repair | 101 | 2.60e-02 | 1.28e-01 | 2.09e-01 |
| Pre-NOTCH Transcription and Translation | 31 | 2.64e-02 | 2.31e-01 | 2.09e-01 |
| Nuclear Envelope Breakdown | 51 | 2.65e-02 | 1.80e-01 | 2.09e-01 |
| CaM pathway | 24 | 2.66e-02 | -2.62e-01 | 2.09e-01 |
| Calmodulin induced events | 24 | 2.66e-02 | -2.62e-01 | 2.09e-01 |
| Amino acids regulate mTORC1 | 51 | 2.67e-02 | 1.79e-01 | 2.09e-01 |
| Extension of Telomeres | 50 | 2.70e-02 | 1.81e-01 | 2.09e-01 |
| Post NMDA receptor activation events | 47 | 2.71e-02 | -1.86e-01 | 2.09e-01 |
| Chromosome Maintenance | 90 | 2.72e-02 | 1.35e-01 | 2.09e-01 |
| Basigin interactions | 20 | 2.75e-02 | 2.85e-01 | 2.10e-01 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | 22 | 2.78e-02 | 2.71e-01 | 2.11e-01 |
| Synthesis of DNA | 116 | 2.79e-02 | 1.18e-01 | 2.11e-01 |
| Apoptosis | 153 | 2.85e-02 | 1.03e-01 | 2.14e-01 |
| Scavenging by Class A Receptors | 11 | 2.87e-02 | 3.81e-01 | 2.15e-01 |
| Activation of ATR in response to replication stress | 37 | 2.89e-02 | 2.08e-01 | 2.15e-01 |
| Viral mRNA Translation | 86 | 3.09e-02 | -1.35e-01 | 2.29e-01 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | 24 | 3.11e-02 | -2.54e-01 | 2.29e-01 |
| Metal ion SLC transporters | 23 | 3.16e-02 | 2.59e-01 | 2.31e-01 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | 50 | 3.18e-02 | -1.76e-01 | 2.31e-01 |
| Signaling by NTRK2 (TRKB) | 20 | 3.29e-02 | -2.76e-01 | 2.37e-01 |
| Resolution of D-Loop Structures | 33 | 3.30e-02 | 2.14e-01 | 2.37e-01 |
| Activation of Matrix Metalloproteinases | 15 | 3.32e-02 | 3.18e-01 | 2.37e-01 |
| Extracellular matrix organization | 183 | 3.32e-02 | 9.15e-02 | 2.37e-01 |
| Mitotic Prometaphase | 181 | 3.41e-02 | 9.15e-02 | 2.42e-01 |
| RHOC GTPase cycle | 67 | 3.50e-02 | 1.49e-01 | 2.44e-01 |
| Presynaptic phase of homologous DNA pairing and strand exchange | 39 | 3.51e-02 | 1.95e-01 | 2.44e-01 |
| Selenoamino acid metabolism | 104 | 3.51e-02 | -1.20e-01 | 2.44e-01 |
| Diseases of glycosylation | 99 | 3.52e-02 | 1.23e-01 | 2.44e-01 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | 32 | 3.52e-02 | 2.15e-01 | 2.44e-01 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | 13 | 3.62e-02 | 3.36e-01 | 2.48e-01 |
| COPI-independent Golgi-to-ER retrograde traffic | 31 | 3.62e-02 | -2.17e-01 | 2.48e-01 |
| rRNA processing in the nucleus and cytosol | 184 | 3.68e-02 | -8.94e-02 | 2.51e-01 |
| Transcriptional regulation by RUNX3 | 91 | 3.69e-02 | 1.27e-01 | 2.51e-01 |
| ROS and RNS production in phagocytes | 27 | 3.85e-02 | 2.30e-01 | 2.59e-01 |
| HDMs demethylate histones | 21 | 3.86e-02 | 2.61e-01 | 2.59e-01 |
| DNA Double-Strand Break Repair | 127 | 4.05e-02 | 1.05e-01 | 2.71e-01 |
| Defective B3GALTL causes PpS | 19 | 4.09e-02 | 2.71e-01 | 2.72e-01 |
| Glucuronidation | 10 | 4.11e-02 | 3.73e-01 | 2.72e-01 |
| Telomere Maintenance | 65 | 4.14e-02 | 1.46e-01 | 2.72e-01 |
| RHOD GTPase cycle | 49 | 4.18e-02 | 1.68e-01 | 2.72e-01 |
| Mitotic G1 phase and G1/S transition | 144 | 4.18e-02 | 9.84e-02 | 2.72e-01 |
| Transcriptional regulation by RUNX1 | 147 | 4.19e-02 | 9.74e-02 | 2.72e-01 |
| Processive synthesis on the C-strand of the telomere | 19 | 4.28e-02 | 2.68e-01 | 2.77e-01 |
| Transport of bile salts and organic acids, metal ions and amine compounds | 58 | 4.45e-02 | 1.53e-01 | 2.84e-01 |
| Ca-dependent events | 25 | 4.46e-02 | -2.32e-01 | 2.84e-01 |
| Glycolysis | 65 | 4.46e-02 | 1.44e-01 | 2.84e-01 |
| Cyclin A/B1/B2 associated events during G2/M transition | 24 | 4.52e-02 | 2.36e-01 | 2.87e-01 |
| Condensation of Prometaphase Chromosomes | 11 | 4.57e-02 | 3.48e-01 | 2.87e-01 |
| Hh mutants abrogate ligand secretion | 55 | 4.58e-02 | 1.56e-01 | 2.87e-01 |
| FRS-mediated FGFR3 signaling | 12 | 4.58e-02 | -3.33e-01 | 2.87e-01 |
| SARS-CoV Infections | 144 | 4.64e-02 | 9.63e-02 | 2.89e-01 |
| Antimicrobial peptides | 17 | 4.66e-02 | 2.79e-01 | 2.89e-01 |
| IRAK4 deficiency (TLR2/4) | 12 | 4.71e-02 | 3.31e-01 | 2.90e-01 |
| Growth hormone receptor signaling | 20 | 4.71e-02 | 2.56e-01 | 2.90e-01 |
| Mitochondrial Fatty Acid Beta-Oxidation | 32 | 4.76e-02 | 2.02e-01 | 2.91e-01 |
| Assembly of the pre-replicative complex | 69 | 4.86e-02 | 1.37e-01 | 2.96e-01 |
| Hh mutants are degraded by ERAD | 53 | 4.96e-02 | 1.56e-01 | 3.01e-01 |
| Signaling by high-kinase activity BRAF mutants | 30 | 5.13e-02 | 2.06e-01 | 3.10e-01 |
| Regulation of localization of FOXO transcription factors | 10 | 5.24e-02 | -3.54e-01 | 3.15e-01 |
| Signaling by Insulin receptor | 59 | 5.29e-02 | 1.46e-01 | 3.17e-01 |
| Peptide ligand-binding receptors | 51 | 5.36e-02 | 1.56e-01 | 3.19e-01 |
| Gamma carboxylation, hypusine formation and arylsulfatase activation | 37 | 5.43e-02 | 1.83e-01 | 3.22e-01 |
| tRNA modification in the nucleus and cytosol | 41 | 5.58e-02 | -1.73e-01 | 3.29e-01 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | 13 | 5.60e-02 | 3.06e-01 | 3.29e-01 |
| Interleukin-1 family signaling | 111 | 5.67e-02 | 1.05e-01 | 3.31e-01 |
| Synthesis of very long-chain fatty acyl-CoAs | 18 | 5.77e-02 | 2.58e-01 | 3.31e-01 |
| tRNA Aminoacylation | 24 | 5.79e-02 | -2.24e-01 | 3.31e-01 |
| Pre-NOTCH Processing in Golgi | 16 | 5.81e-02 | 2.74e-01 | 3.31e-01 |
| Peroxisomal protein import | 57 | 5.84e-02 | 1.45e-01 | 3.31e-01 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | 88 | 5.86e-02 | 1.17e-01 | 3.31e-01 |
| Toll Like Receptor 2 (TLR2) Cascade | 88 | 5.86e-02 | 1.17e-01 | 3.31e-01 |
| Toll Like Receptor TLR1:TLR2 Cascade | 88 | 5.86e-02 | 1.17e-01 | 3.31e-01 |
| Toll Like Receptor TLR6:TLR2 Cascade | 88 | 5.86e-02 | 1.17e-01 | 3.31e-01 |
| Chylomicron assembly | 10 | 5.90e-02 | 3.45e-01 | 3.31e-01 |
| G2/M Checkpoints | 130 | 5.91e-02 | 9.60e-02 | 3.31e-01 |
| RAC3 GTPase cycle | 79 | 5.92e-02 | 1.23e-01 | 3.31e-01 |
| Cleavage of the damaged pyrimidine | 16 | 5.99e-02 | 2.72e-01 | 3.31e-01 |
| Depyrimidination | 16 | 5.99e-02 | 2.72e-01 | 3.31e-01 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | 16 | 5.99e-02 | 2.72e-01 | 3.31e-01 |
| G1/S Transition | 127 | 6.08e-02 | 9.65e-02 | 3.34e-01 |
| Transcriptional regulation of granulopoiesis | 25 | 6.12e-02 | 2.16e-01 | 3.34e-01 |
| PERK regulates gene expression | 31 | 6.17e-02 | 1.94e-01 | 3.34e-01 |
| Regulation of FOXO transcriptional activity by acetylation | 10 | 6.21e-02 | 3.41e-01 | 3.34e-01 |
| Programmed Cell Death | 177 | 6.22e-02 | 8.14e-02 | 3.34e-01 |
| Voltage gated Potassium channels | 12 | 6.23e-02 | -3.11e-01 | 3.34e-01 |
| Major pathway of rRNA processing in the nucleolus and cytosol | 174 | 6.24e-02 | -8.21e-02 | 3.34e-01 |
| Base Excision Repair | 45 | 6.25e-02 | 1.61e-01 | 3.34e-01 |
| RHOB GTPase cycle | 63 | 6.25e-02 | 1.36e-01 | 3.34e-01 |
| Vasopressin regulates renal water homeostasis via Aquaporins | 24 | 6.37e-02 | -2.19e-01 | 3.39e-01 |
| Signaling by NTRK1 (TRKA) | 102 | 6.47e-02 | 1.06e-01 | 3.43e-01 |
| Diseases of DNA repair | 34 | 6.54e-02 | 1.83e-01 | 3.45e-01 |
| Plasma lipoprotein clearance | 32 | 6.64e-02 | 1.88e-01 | 3.47e-01 |
| Ion channel transport | 116 | 6.69e-02 | 9.86e-02 | 3.47e-01 |
| MAPK1/MAPK3 signaling | 212 | 6.70e-02 | 7.32e-02 | 3.47e-01 |
| Estrogen-dependent gene expression | 84 | 6.70e-02 | 1.16e-01 | 3.47e-01 |
| rRNA processing | 205 | 6.71e-02 | -7.44e-02 | 3.47e-01 |
| Translesion Synthesis by POLH | 18 | 6.74e-02 | 2.49e-01 | 3.48e-01 |
| Metabolism of nucleotides | 86 | 6.95e-02 | 1.13e-01 | 3.57e-01 |
| Zinc transporters | 15 | 6.98e-02 | 2.70e-01 | 3.57e-01 |
| Peroxisomal lipid metabolism | 26 | 7.00e-02 | 2.05e-01 | 3.57e-01 |
| COPI-mediated anterograde transport | 74 | 7.10e-02 | 1.21e-01 | 3.61e-01 |
| RAF/MAP kinase cascade | 207 | 7.22e-02 | 7.27e-02 | 3.65e-01 |
| Eukaryotic Translation Termination | 89 | 7.25e-02 | -1.10e-01 | 3.65e-01 |
| RND1 GTPase cycle | 37 | 7.27e-02 | 1.71e-01 | 3.65e-01 |
| Interleukin-37 signaling | 15 | 7.33e-02 | 2.67e-01 | 3.67e-01 |
| Meiotic recombination | 22 | 7.37e-02 | 2.20e-01 | 3.68e-01 |
| Acyl chain remodelling of PC | 11 | 7.41e-02 | 3.11e-01 | 3.68e-01 |
| RORA activates gene expression | 18 | 7.48e-02 | 2.43e-01 | 3.70e-01 |
| Depolymerisation of the Nuclear Lamina | 14 | 7.60e-02 | 2.74e-01 | 3.75e-01 |
| Retrograde neurotrophin signalling | 10 | 7.62e-02 | 3.24e-01 | 3.75e-01 |
| The citric acid (TCA) cycle and respiratory electron transport | 151 | 7.74e-02 | -8.34e-02 | 3.79e-01 |
| Glycogen breakdown (glycogenolysis) | 15 | 7.93e-02 | -2.62e-01 | 3.87e-01 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | 16 | 8.12e-02 | 2.52e-01 | 3.95e-01 |
| Glucose metabolism | 81 | 8.22e-02 | 1.12e-01 | 3.98e-01 |
| Signaling by BRAF and RAF1 fusions | 55 | 8.27e-02 | 1.35e-01 | 4.00e-01 |
| Base-Excision Repair, AP Site Formation | 18 | 8.32e-02 | 2.36e-01 | 4.00e-01 |
| Sphingolipid metabolism | 77 | 8.35e-02 | 1.14e-01 | 4.01e-01 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | 91 | 8.42e-02 | -1.05e-01 | 4.02e-01 |
| MAPK family signaling cascades | 244 | 8.52e-02 | 6.42e-02 | 4.06e-01 |
| ERKs are inactivated | 13 | 8.61e-02 | 2.75e-01 | 4.08e-01 |
| PI-3K cascade:FGFR3 | 10 | 8.75e-02 | -3.12e-01 | 4.08e-01 |
| Collagen chain trimerization | 18 | 8.78e-02 | 2.32e-01 | 4.08e-01 |
| RAC2 GTPase cycle | 75 | 8.78e-02 | 1.14e-01 | 4.08e-01 |
| Formation of Fibrin Clot (Clotting Cascade) | 28 | 8.79e-02 | 1.86e-01 | 4.08e-01 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | 170 | 8.80e-02 | 7.60e-02 | 4.08e-01 |
| Transcriptional activation of mitochondrial biogenesis | 50 | 8.80e-02 | 1.40e-01 | 4.08e-01 |
| CDC42 GTPase cycle | 130 | 8.81e-02 | 8.68e-02 | 4.08e-01 |
| Mitochondrial translation | 93 | 8.87e-02 | -1.02e-01 | 4.10e-01 |
| L13a-mediated translational silencing of Ceruloplasmin expression | 108 | 9.02e-02 | -9.45e-02 | 4.16e-01 |
| Diseases of metabolism | 179 | 9.14e-02 | 7.33e-02 | 4.20e-01 |
| Circadian Clock | 65 | 9.18e-02 | 1.21e-01 | 4.20e-01 |
| Interleukin-1 signaling | 92 | 9.27e-02 | 1.02e-01 | 4.20e-01 |
| Signaling by FGFR3 in disease | 14 | 9.28e-02 | -2.59e-01 | 4.20e-01 |
| Signaling by FGFR3 point mutants in cancer | 14 | 9.28e-02 | -2.59e-01 | 4.20e-01 |
| Fertilization | 10 | 9.53e-02 | -3.05e-01 | 4.29e-01 |
| GABA synthesis, release, reuptake and degradation | 11 | 9.55e-02 | 2.90e-01 | 4.29e-01 |
| TP53 Regulates Transcription of Death Receptors and Ligands | 11 | 9.59e-02 | 2.90e-01 | 4.29e-01 |
| Transcriptional Regulation by TP53 | 351 | 9.60e-02 | 5.19e-02 | 4.29e-01 |
| Mitochondrial translation initiation | 87 | 9.65e-02 | -1.03e-01 | 4.30e-01 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | 21 | 9.68e-02 | 2.09e-01 | 4.30e-01 |
| Signaling by NOTCH | 156 | 9.71e-02 | 7.71e-02 | 4.30e-01 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | 10 | 9.86e-02 | 3.02e-01 | 4.34e-01 |
| FOXO-mediated transcription | 52 | 9.87e-02 | 1.32e-01 | 4.34e-01 |
| Deubiquitination | 218 | 9.92e-02 | 6.50e-02 | 4.34e-01 |
| Aquaporin-mediated transport | 28 | 9.93e-02 | -1.80e-01 | 4.34e-01 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | 14 | 9.99e-02 | 2.54e-01 | 4.36e-01 |
| Removal of the Flap Intermediate from the C-strand | 17 | 1.01e-01 | 2.30e-01 | 4.41e-01 |
| Golgi Cisternae Pericentriolar Stack Reorganization | 14 | 1.02e-01 | 2.53e-01 | 4.41e-01 |
| O-glycosylation of TSR domain-containing proteins | 20 | 1.02e-01 | 2.11e-01 | 4.41e-01 |
| Regulation of HMOX1 expression and activity | 62 | 1.03e-01 | 1.20e-01 | 4.41e-01 |
| Downstream signaling of activated FGFR3 | 17 | 1.04e-01 | -2.27e-01 | 4.48e-01 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | 14 | 1.05e-01 | 2.50e-01 | 4.48e-01 |
| Diseases of signal transduction by growth factor receptors and second messengers | 361 | 1.05e-01 | 4.98e-02 | 4.49e-01 |
| DAG and IP3 signaling | 30 | 1.06e-01 | -1.71e-01 | 4.49e-01 |
| Metabolism of vitamins and cofactors | 160 | 1.06e-01 | 7.41e-02 | 4.50e-01 |
| Antigen processing-Cross presentation | 87 | 1.07e-01 | 1.00e-01 | 4.50e-01 |
| Neurotransmitter release cycle | 31 | 1.07e-01 | 1.67e-01 | 4.50e-01 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | 30 | 1.08e-01 | -1.70e-01 | 4.52e-01 |
| Pentose phosphate pathway | 13 | 1.08e-01 | -2.58e-01 | 4.52e-01 |
| Synthesis of PC | 24 | 1.10e-01 | 1.89e-01 | 4.55e-01 |
| Cap-dependent Translation Initiation | 116 | 1.10e-01 | -8.61e-02 | 4.55e-01 |
| Eukaryotic Translation Initiation | 116 | 1.10e-01 | -8.61e-02 | 4.55e-01 |
| Signaling by cytosolic FGFR1 fusion mutants | 17 | 1.10e-01 | 2.24e-01 | 4.55e-01 |
| Nuclear Envelope (NE) Reassembly | 69 | 1.11e-01 | 1.11e-01 | 4.57e-01 |
| Negative regulation of MAPK pathway | 41 | 1.12e-01 | 1.44e-01 | 4.57e-01 |
| Termination of O-glycan biosynthesis | 10 | 1.12e-01 | 2.90e-01 | 4.57e-01 |
| Nef mediated downregulation of MHC class I complex cell surface expression | 10 | 1.13e-01 | -2.90e-01 | 4.57e-01 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | 109 | 1.13e-01 | -8.81e-02 | 4.57e-01 |
| Interferon alpha/beta signaling | 45 | 1.13e-01 | 1.37e-01 | 4.57e-01 |
| Suppression of phagosomal maturation | 12 | 1.13e-01 | 2.64e-01 | 4.57e-01 |
| Assembly and cell surface presentation of NMDA receptors | 17 | 1.14e-01 | -2.22e-01 | 4.57e-01 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | 111 | 1.14e-01 | -8.70e-02 | 4.57e-01 |
| Nonsense-Mediated Decay (NMD) | 111 | 1.14e-01 | -8.70e-02 | 4.57e-01 |
| RAF-independent MAPK1/3 activation | 21 | 1.15e-01 | 1.99e-01 | 4.60e-01 |
| Uptake and function of anthrax toxins | 11 | 1.16e-01 | 2.74e-01 | 4.60e-01 |
| Protein localization | 150 | 1.16e-01 | 7.45e-02 | 4.60e-01 |
| Diseases associated with O-glycosylation of proteins | 36 | 1.16e-01 | 1.51e-01 | 4.60e-01 |
| Synthesis of PIPs at the plasma membrane | 45 | 1.17e-01 | -1.35e-01 | 4.63e-01 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | 25 | 1.17e-01 | 1.81e-01 | 4.63e-01 |
| SARS-CoV-1 Infection | 48 | 1.18e-01 | 1.31e-01 | 4.64e-01 |
| Signaling by NOTCH3 | 37 | 1.19e-01 | 1.48e-01 | 4.67e-01 |
| Signaling by Hippo | 18 | 1.20e-01 | -2.12e-01 | 4.67e-01 |
| Activation of BAD and translocation to mitochondria | 14 | 1.20e-01 | -2.40e-01 | 4.67e-01 |
| COPII-mediated vesicle transport | 63 | 1.21e-01 | 1.13e-01 | 4.69e-01 |
| TNFR2 non-canonical NF-kB pathway | 77 | 1.22e-01 | -1.02e-01 | 4.72e-01 |
| Synthesis of PA | 25 | 1.22e-01 | 1.79e-01 | 4.72e-01 |
| Translesion synthesis by POLI | 17 | 1.23e-01 | 2.16e-01 | 4.73e-01 |
| MAP2K and MAPK activation | 34 | 1.23e-01 | 1.53e-01 | 4.73e-01 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | 15 | 1.24e-01 | -2.30e-01 | 4.74e-01 |
| Gene Silencing by RNA | 68 | 1.26e-01 | 1.07e-01 | 4.81e-01 |
| Transmission across Chemical Synapses | 146 | 1.26e-01 | -7.34e-02 | 4.81e-01 |
| ER-Phagosome pathway | 79 | 1.28e-01 | 9.92e-02 | 4.87e-01 |
| Sensory perception of taste | 13 | 1.29e-01 | 2.43e-01 | 4.88e-01 |
| trans-Golgi Network Vesicle Budding | 68 | 1.29e-01 | 1.07e-01 | 4.88e-01 |
| Recycling of bile acids and salts | 13 | 1.30e-01 | 2.43e-01 | 4.90e-01 |
| DARPP-32 events | 20 | 1.31e-01 | -1.95e-01 | 4.93e-01 |
| Interleukin-6 family signaling | 19 | 1.32e-01 | 2.00e-01 | 4.93e-01 |
| Diseases associated with glycosylation precursor biosynthesis | 18 | 1.32e-01 | 2.05e-01 | 4.93e-01 |
| Glycosaminoglycan metabolism | 90 | 1.32e-01 | 9.19e-02 | 4.94e-01 |
| The NLRP3 inflammasome | 14 | 1.33e-01 | 2.32e-01 | 4.94e-01 |
| GPCR ligand binding | 128 | 1.34e-01 | 7.69e-02 | 4.96e-01 |
| RHOG GTPase cycle | 66 | 1.34e-01 | 1.07e-01 | 4.96e-01 |
| Glucagon signaling in metabolic regulation | 19 | 1.35e-01 | -1.98e-01 | 4.96e-01 |
| Cargo concentration in the ER | 27 | 1.35e-01 | 1.66e-01 | 4.96e-01 |
| Rap1 signalling | 11 | 1.35e-01 | -2.60e-01 | 4.96e-01 |
| Collagen formation | 53 | 1.35e-01 | 1.19e-01 | 4.96e-01 |
| Recognition of DNA damage by PCNA-containing replication complex | 30 | 1.37e-01 | 1.57e-01 | 4.99e-01 |
| Cytoprotection by HMOX1 | 118 | 1.38e-01 | 7.92e-02 | 5.01e-01 |
| Amyloid fiber formation | 41 | 1.38e-01 | 1.34e-01 | 5.01e-01 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | 98 | 1.38e-01 | -8.68e-02 | 5.01e-01 |
| Interleukin-4 and Interleukin-13 signaling | 66 | 1.40e-01 | 1.05e-01 | 5.04e-01 |
| Orc1 removal from chromatin | 67 | 1.40e-01 | 1.04e-01 | 5.04e-01 |
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | 12 | 1.40e-01 | -2.46e-01 | 5.04e-01 |
| Autophagy | 121 | 1.40e-01 | 7.77e-02 | 5.04e-01 |
| Mitochondrial translation elongation | 87 | 1.43e-01 | -9.10e-02 | 5.11e-01 |
| DNA Repair | 276 | 1.44e-01 | 5.13e-02 | 5.11e-01 |
| Negative regulation of FLT3 | 13 | 1.44e-01 | 2.34e-01 | 5.11e-01 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | 31 | 1.44e-01 | -1.52e-01 | 5.11e-01 |
| Lysosome Vesicle Biogenesis | 31 | 1.44e-01 | 1.52e-01 | 5.11e-01 |
| Establishment of Sister Chromatid Cohesion | 11 | 1.45e-01 | -2.54e-01 | 5.11e-01 |
| G0 and Early G1 | 26 | 1.46e-01 | 1.65e-01 | 5.14e-01 |
| PCNA-Dependent Long Patch Base Excision Repair | 21 | 1.47e-01 | 1.83e-01 | 5.15e-01 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | 12 | 1.49e-01 | 2.41e-01 | 5.19e-01 |
| Polo-like kinase mediated events | 16 | 1.49e-01 | 2.08e-01 | 5.19e-01 |
| Interleukin-15 signaling | 12 | 1.49e-01 | 2.41e-01 | 5.19e-01 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | 42 | 1.49e-01 | 1.29e-01 | 5.19e-01 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | 12 | 1.50e-01 | 2.40e-01 | 5.21e-01 |
| Killing mechanisms | 10 | 1.51e-01 | -2.62e-01 | 5.21e-01 |
| WNT5:FZD7-mediated leishmania damping | 10 | 1.51e-01 | -2.62e-01 | 5.21e-01 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | 24 | 1.52e-01 | 1.69e-01 | 5.22e-01 |
| Interleukin-10 signaling | 18 | 1.52e-01 | 1.95e-01 | 5.22e-01 |
| TGF-beta receptor signaling activates SMADs | 31 | 1.52e-01 | 1.49e-01 | 5.22e-01 |
| p130Cas linkage to MAPK signaling for integrins | 13 | 1.54e-01 | 2.28e-01 | 5.26e-01 |
| RND3 GTPase cycle | 36 | 1.55e-01 | 1.37e-01 | 5.26e-01 |
| Defective pyroptosis | 13 | 1.55e-01 | 2.28e-01 | 5.26e-01 |
| Role of LAT2/NTAL/LAB on calcium mobilization | 12 | 1.57e-01 | -2.36e-01 | 5.31e-01 |
| RHOA GTPase cycle | 129 | 1.58e-01 | 7.21e-02 | 5.35e-01 |
| Mitochondrial tRNA aminoacylation | 18 | 1.58e-01 | -1.92e-01 | 5.35e-01 |
| Golgi-to-ER retrograde transport | 106 | 1.59e-01 | 7.93e-02 | 5.36e-01 |
| Meiosis | 46 | 1.60e-01 | 1.20e-01 | 5.38e-01 |
| Glycerophospholipid biosynthesis | 90 | 1.62e-01 | 8.54e-02 | 5.40e-01 |
| G1/S-Specific Transcription | 28 | 1.62e-01 | 1.53e-01 | 5.40e-01 |
| FGFR1 mutant receptor activation | 23 | 1.62e-01 | 1.68e-01 | 5.40e-01 |
| Vesicle-mediated transport | 555 | 1.63e-01 | 3.49e-02 | 5.40e-01 |
| HDACs deacetylate histones | 32 | 1.63e-01 | -1.42e-01 | 5.40e-01 |
| Regulation of gene expression in beta cells | 13 | 1.64e-01 | -2.23e-01 | 5.40e-01 |
| Antiviral mechanism by IFN-stimulated genes | 77 | 1.64e-01 | 9.18e-02 | 5.40e-01 |
| MET promotes cell motility | 27 | 1.64e-01 | -1.55e-01 | 5.40e-01 |
| Transport of inorganic cations/anions and amino acids/oligopeptides | 71 | 1.64e-01 | 9.55e-02 | 5.40e-01 |
| Influenza Viral RNA Transcription and Replication | 132 | 1.65e-01 | -7.01e-02 | 5.40e-01 |
| Macroautophagy | 108 | 1.66e-01 | 7.72e-02 | 5.40e-01 |
| BBSome-mediated cargo-targeting to cilium | 23 | 1.66e-01 | 1.67e-01 | 5.40e-01 |
| Signaling by NOTCH4 | 75 | 1.66e-01 | 9.25e-02 | 5.40e-01 |
| RHOV GTPase cycle | 35 | 1.66e-01 | 1.35e-01 | 5.40e-01 |
| Early Phase of HIV Life Cycle | 12 | 1.68e-01 | 2.30e-01 | 5.41e-01 |
| MyD88 cascade initiated on plasma membrane | 77 | 1.68e-01 | 9.09e-02 | 5.41e-01 |
| Toll Like Receptor 10 (TLR10) Cascade | 77 | 1.68e-01 | 9.09e-02 | 5.41e-01 |
| Toll Like Receptor 5 (TLR5) Cascade | 77 | 1.68e-01 | 9.09e-02 | 5.41e-01 |
| Signaling by Nuclear Receptors | 197 | 1.68e-01 | 5.70e-02 | 5.41e-01 |
| NR1H2 and NR1H3-mediated signaling | 40 | 1.70e-01 | 1.26e-01 | 5.43e-01 |
| Lewis blood group biosynthesis | 11 | 1.72e-01 | 2.38e-01 | 5.48e-01 |
| Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | 108 | 1.72e-01 | -7.61e-02 | 5.48e-01 |
| Uptake and actions of bacterial toxins | 22 | 1.73e-01 | 1.68e-01 | 5.48e-01 |
| Transcriptional Regulation by VENTX | 35 | 1.73e-01 | -1.33e-01 | 5.48e-01 |
| Phase I - Functionalization of compounds | 74 | 1.73e-01 | 9.17e-02 | 5.48e-01 |
| PLC beta mediated events | 33 | 1.74e-01 | -1.37e-01 | 5.48e-01 |
| HDR through Single Strand Annealing (SSA) | 37 | 1.74e-01 | 1.29e-01 | 5.48e-01 |
| Prolonged ERK activation events | 12 | 1.74e-01 | 2.27e-01 | 5.48e-01 |
| Signalling to ERKs | 31 | 1.75e-01 | 1.41e-01 | 5.49e-01 |
| Miscellaneous transport and binding events | 21 | 1.76e-01 | 1.71e-01 | 5.51e-01 |
| Nicotinate metabolism | 23 | 1.77e-01 | -1.63e-01 | 5.51e-01 |
| Respiratory electron transport | 103 | 1.77e-01 | -7.71e-02 | 5.51e-01 |
| Translesion synthesis by REV1 | 16 | 1.77e-01 | 1.95e-01 | 5.51e-01 |
| Receptor Mediated Mitophagy | 10 | 1.78e-01 | 2.46e-01 | 5.51e-01 |
| Metabolism of fat-soluble vitamins | 39 | 1.80e-01 | 1.24e-01 | 5.57e-01 |
| Phase 0 - rapid depolarisation | 17 | 1.81e-01 | -1.88e-01 | 5.57e-01 |
| Resolution of Abasic Sites (AP sites) | 37 | 1.82e-01 | 1.27e-01 | 5.62e-01 |
| Complex I biogenesis | 57 | 1.83e-01 | -1.02e-01 | 5.63e-01 |
| Transport of the SLBP Dependant Mature mRNA | 35 | 1.86e-01 | 1.29e-01 | 5.69e-01 |
| Tight junction interactions | 21 | 1.87e-01 | 1.67e-01 | 5.71e-01 |
| Translation of Structural Proteins | 27 | 1.88e-01 | 1.46e-01 | 5.74e-01 |
| Other semaphorin interactions | 10 | 1.89e-01 | 2.40e-01 | 5.76e-01 |
| Intrinsic Pathway of Fibrin Clot Formation | 18 | 1.90e-01 | 1.78e-01 | 5.78e-01 |
| Processing of DNA double-strand break ends | 62 | 1.93e-01 | 9.57e-02 | 5.84e-01 |
| PCP/CE pathway | 79 | 1.95e-01 | 8.45e-02 | 5.88e-01 |
| Retrograde transport at the Trans-Golgi-Network | 48 | 1.95e-01 | 1.08e-01 | 5.88e-01 |
| Regulation of RUNX2 expression and activity | 62 | 1.95e-01 | 9.52e-02 | 5.88e-01 |
| Blood group systems biosynthesis | 13 | 1.96e-01 | 2.07e-01 | 5.88e-01 |
| Vpr-mediated nuclear import of PICs | 33 | 1.97e-01 | 1.30e-01 | 5.90e-01 |
| O-linked glycosylation | 64 | 1.98e-01 | 9.31e-02 | 5.92e-01 |
| Interactions of Vpr with host cellular proteins | 36 | 1.98e-01 | 1.24e-01 | 5.92e-01 |
| Cleavage of the damaged purine | 11 | 2.00e-01 | 2.23e-01 | 5.94e-01 |
| Depurination | 11 | 2.00e-01 | 2.23e-01 | 5.94e-01 |
| Recognition and association of DNA glycosylase with site containing an affected purine | 11 | 2.00e-01 | 2.23e-01 | 5.94e-01 |
| ESR-mediated signaling | 138 | 2.00e-01 | 6.32e-02 | 5.94e-01 |
| Mitochondrial biogenesis | 71 | 2.01e-01 | 8.77e-02 | 5.95e-01 |
| FRS-mediated FGFR1 signaling | 12 | 2.03e-01 | -2.12e-01 | 5.99e-01 |
| Mitotic Telophase/Cytokinesis | 13 | 2.04e-01 | -2.04e-01 | 5.99e-01 |
| TICAM1-dependent activation of IRF3/IRF7 | 10 | 2.04e-01 | -2.32e-01 | 5.99e-01 |
| Toll Like Receptor 4 (TLR4) Cascade | 110 | 2.05e-01 | 7.00e-02 | 6.01e-01 |
| FRS-mediated FGFR2 signaling | 12 | 2.06e-01 | -2.11e-01 | 6.01e-01 |
| Glutathione conjugation | 29 | 2.07e-01 | 1.35e-01 | 6.02e-01 |
| Role of phospholipids in phagocytosis | 17 | 2.07e-01 | 1.77e-01 | 6.02e-01 |
| Signaling by BMP | 16 | 2.08e-01 | -1.82e-01 | 6.02e-01 |
| Chondroitin sulfate biosynthesis | 14 | 2.08e-01 | 1.95e-01 | 6.02e-01 |
| Retinoid metabolism and transport | 35 | 2.09e-01 | 1.23e-01 | 6.03e-01 |
| FRS-mediated FGFR4 signaling | 12 | 2.09e-01 | -2.09e-01 | 6.03e-01 |
| Chondroitin sulfate/dermatan sulfate metabolism | 40 | 2.10e-01 | 1.15e-01 | 6.03e-01 |
| Transport of Mature mRNA Derived from an Intronless Transcript | 41 | 2.11e-01 | 1.13e-01 | 6.03e-01 |
| Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon | 14 | 2.11e-01 | -1.93e-01 | 6.03e-01 |
| Arachidonic acid metabolism | 30 | 2.11e-01 | 1.32e-01 | 6.03e-01 |
| Translesion synthesis by POLK | 17 | 2.12e-01 | 1.75e-01 | 6.03e-01 |
| Signaling by Hedgehog | 116 | 2.12e-01 | 6.72e-02 | 6.03e-01 |
| Elastic fibre formation | 28 | 2.13e-01 | 1.36e-01 | 6.03e-01 |
| Tie2 Signaling | 14 | 2.13e-01 | -1.92e-01 | 6.03e-01 |
| tRNA processing in the mitochondrion | 17 | 2.14e-01 | 1.74e-01 | 6.03e-01 |
| Postmitotic nuclear pore complex (NPC) reformation | 27 | 2.15e-01 | 1.38e-01 | 6.03e-01 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | 10 | 2.16e-01 | 2.26e-01 | 6.03e-01 |
| Toll-like Receptor Cascades | 126 | 2.16e-01 | 6.39e-02 | 6.03e-01 |
| MyD88 dependent cascade initiated on endosome | 81 | 2.16e-01 | 7.96e-02 | 6.03e-01 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | 81 | 2.16e-01 | 7.96e-02 | 6.03e-01 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | 81 | 2.16e-01 | 7.96e-02 | 6.03e-01 |
| Mitochondrial translation termination | 87 | 2.17e-01 | -7.67e-02 | 6.03e-01 |
| Developmental Biology | 677 | 2.17e-01 | 2.81e-02 | 6.03e-01 |
| S Phase | 157 | 2.17e-01 | 5.72e-02 | 6.03e-01 |
| Nuclear Receptor transcription pathway | 41 | 2.17e-01 | 1.11e-01 | 6.03e-01 |
| FOXO-mediated transcription of cell death genes | 15 | 2.19e-01 | 1.83e-01 | 6.03e-01 |
| Laminin interactions | 21 | 2.19e-01 | -1.55e-01 | 6.03e-01 |
| Synthesis of PIPs at the early endosome membrane | 15 | 2.19e-01 | -1.83e-01 | 6.03e-01 |
| Metabolism of water-soluble vitamins and cofactors | 104 | 2.20e-01 | 6.97e-02 | 6.03e-01 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | 38 | 2.21e-01 | 1.15e-01 | 6.03e-01 |
| Signaling by RAS mutants | 38 | 2.21e-01 | 1.15e-01 | 6.03e-01 |
| Signaling by moderate kinase activity BRAF mutants | 38 | 2.21e-01 | 1.15e-01 | 6.03e-01 |
| Signaling downstream of RAS mutants | 38 | 2.21e-01 | 1.15e-01 | 6.03e-01 |
| SUMOylation of DNA replication proteins | 45 | 2.23e-01 | 1.05e-01 | 6.08e-01 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | 21 | 2.25e-01 | -1.53e-01 | 6.10e-01 |
| Trafficking of AMPA receptors | 21 | 2.25e-01 | -1.53e-01 | 6.10e-01 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | 33 | 2.26e-01 | 1.22e-01 | 6.10e-01 |
| Hedgehog ‘on’ state | 75 | 2.26e-01 | 8.09e-02 | 6.10e-01 |
| RHO GTPases activate CIT | 19 | 2.26e-01 | 1.60e-01 | 6.10e-01 |
| RAC1 GTPase cycle | 149 | 2.27e-01 | 5.74e-02 | 6.10e-01 |
| HSF1 activation | 24 | 2.27e-01 | 1.42e-01 | 6.10e-01 |
| Mucopolysaccharidoses | 11 | 2.28e-01 | 2.10e-01 | 6.10e-01 |
| SLC transporter disorders | 70 | 2.28e-01 | 8.35e-02 | 6.10e-01 |
| Toll Like Receptor 9 (TLR9) Cascade | 85 | 2.29e-01 | 7.55e-02 | 6.14e-01 |
| Regulation of expression of SLITs and ROBOs | 157 | 2.30e-01 | -5.56e-02 | 6.14e-01 |
| Cell recruitment (pro-inflammatory response) | 19 | 2.31e-01 | 1.59e-01 | 6.14e-01 |
| Purinergic signaling in leishmaniasis infection | 19 | 2.31e-01 | 1.59e-01 | 6.14e-01 |
| Transcriptional regulation by small RNAs | 47 | 2.32e-01 | 1.01e-01 | 6.14e-01 |
| Gamma-carboxylation, transport, and amino-terminal cleavage of proteins | 10 | 2.34e-01 | 2.18e-01 | 6.18e-01 |
| Other interleukin signaling | 18 | 2.34e-01 | 1.62e-01 | 6.18e-01 |
| Signaling by NODAL | 15 | 2.34e-01 | 1.77e-01 | 6.18e-01 |
| Nuclear Pore Complex (NPC) Disassembly | 35 | 2.35e-01 | 1.16e-01 | 6.18e-01 |
| G-protein mediated events | 37 | 2.35e-01 | -1.13e-01 | 6.18e-01 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | 24 | 2.36e-01 | -1.40e-01 | 6.19e-01 |
| Aflatoxin activation and detoxification | 15 | 2.37e-01 | -1.76e-01 | 6.19e-01 |
| Oxidative Stress Induced Senescence | 63 | 2.38e-01 | 8.61e-02 | 6.19e-01 |
| SHC1 events in ERBB2 signaling | 15 | 2.38e-01 | 1.76e-01 | 6.19e-01 |
| Neuronal System | 207 | 2.39e-01 | -4.76e-02 | 6.19e-01 |
| Organelle biogenesis and maintenance | 243 | 2.39e-01 | 4.40e-02 | 6.19e-01 |
| Interleukin-6 signaling | 10 | 2.40e-01 | 2.15e-01 | 6.19e-01 |
| Mismatch Repair | 15 | 2.40e-01 | 1.75e-01 | 6.19e-01 |
| Signaling by NTRKs | 115 | 2.41e-01 | 6.34e-02 | 6.19e-01 |
| Semaphorin interactions | 51 | 2.41e-01 | 9.50e-02 | 6.19e-01 |
| Downregulation of TGF-beta receptor signaling | 25 | 2.41e-01 | 1.36e-01 | 6.19e-01 |
| Citric acid cycle (TCA cycle) | 21 | 2.41e-01 | -1.48e-01 | 6.19e-01 |
| Signaling by FGFR3 fusions in cancer | 10 | 2.46e-01 | -2.12e-01 | 6.29e-01 |
| Diseases of mitotic cell cycle | 37 | 2.46e-01 | -1.10e-01 | 6.29e-01 |
| Vitamin B5 (pantothenate) metabolism | 16 | 2.47e-01 | 1.67e-01 | 6.29e-01 |
| Adaptive Immune System | 551 | 2.47e-01 | 2.90e-02 | 6.29e-01 |
| Signaling by TGF-beta Receptor Complex | 73 | 2.47e-01 | 7.84e-02 | 6.29e-01 |
| ISG15 antiviral mechanism | 72 | 2.49e-01 | 7.86e-02 | 6.29e-01 |
| MicroRNA (miRNA) biogenesis | 24 | 2.49e-01 | 1.36e-01 | 6.29e-01 |
| G alpha (s) signalling events | 50 | 2.49e-01 | 9.43e-02 | 6.29e-01 |
| Heparan sulfate/heparin (HS-GAG) metabolism | 36 | 2.49e-01 | 1.11e-01 | 6.29e-01 |
| Caspase-mediated cleavage of cytoskeletal proteins | 11 | 2.50e-01 | 2.00e-01 | 6.29e-01 |
| Effects of PIP2 hydrolysis | 18 | 2.50e-01 | 1.57e-01 | 6.29e-01 |
| Oncogenic MAPK signaling | 72 | 2.51e-01 | 7.84e-02 | 6.30e-01 |
| Potassium Channels | 37 | 2.51e-01 | -1.09e-01 | 6.30e-01 |
| Transport of Ribonucleoproteins into the Host Nucleus | 31 | 2.52e-01 | 1.19e-01 | 6.30e-01 |
| Listeria monocytogenes entry into host cells | 18 | 2.55e-01 | 1.55e-01 | 6.35e-01 |
| Beta-catenin phosphorylation cascade | 17 | 2.56e-01 | 1.59e-01 | 6.35e-01 |
| Unblocking of NMDA receptors, glutamate binding and activation | 11 | 2.56e-01 | -1.98e-01 | 6.35e-01 |
| Cell-Cell communication | 90 | 2.56e-01 | 6.93e-02 | 6.35e-01 |
| Josephin domain DUBs | 10 | 2.56e-01 | 2.07e-01 | 6.35e-01 |
| Cytosolic sulfonation of small molecules | 20 | 2.57e-01 | 1.46e-01 | 6.35e-01 |
| Pyrimidine salvage | 10 | 2.57e-01 | 2.07e-01 | 6.35e-01 |
| RHOU GTPase cycle | 36 | 2.57e-01 | 1.09e-01 | 6.35e-01 |
| Keratinization | 29 | 2.58e-01 | 1.21e-01 | 6.37e-01 |
| Cell junction organization | 64 | 2.60e-01 | 8.14e-02 | 6.37e-01 |
| Deposition of new CENPA-containing nucleosomes at the centromere | 27 | 2.61e-01 | 1.25e-01 | 6.37e-01 |
| Nucleosome assembly | 27 | 2.61e-01 | 1.25e-01 | 6.37e-01 |
| TICAM1, RIP1-mediated IKK complex recruitment | 17 | 2.61e-01 | -1.58e-01 | 6.37e-01 |
| Transport of vitamins, nucleosides, and related molecules | 33 | 2.61e-01 | 1.13e-01 | 6.37e-01 |
| DAP12 interactions | 24 | 2.62e-01 | -1.32e-01 | 6.38e-01 |
| Class A/1 (Rhodopsin-like receptors) | 84 | 2.62e-01 | 7.08e-02 | 6.38e-01 |
| Gluconeogenesis | 27 | 2.64e-01 | 1.24e-01 | 6.40e-01 |
| Signaling by ROBO receptors | 193 | 2.64e-01 | -4.67e-02 | 6.40e-01 |
| Transport of the SLBP independent Mature mRNA | 34 | 2.65e-01 | 1.11e-01 | 6.40e-01 |
| TAK1 activates NFkB by phosphorylation and activation of IKKs complex | 24 | 2.66e-01 | 1.31e-01 | 6.40e-01 |
| E2F mediated regulation of DNA replication | 22 | 2.66e-01 | 1.37e-01 | 6.40e-01 |
| Sema4D induced cell migration and growth-cone collapse | 20 | 2.66e-01 | 1.44e-01 | 6.40e-01 |
| UCH proteinases | 81 | 2.66e-01 | 7.15e-02 | 6.40e-01 |
| Degradation of beta-catenin by the destruction complex | 80 | 2.67e-01 | 7.19e-02 | 6.40e-01 |
| Cristae formation | 13 | 2.68e-01 | 1.77e-01 | 6.42e-01 |
| Sema4D in semaphorin signaling | 24 | 2.69e-01 | 1.30e-01 | 6.43e-01 |
| Inflammasomes | 18 | 2.70e-01 | 1.50e-01 | 6.44e-01 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | 20 | 2.70e-01 | -1.42e-01 | 6.44e-01 |
| Pyroptosis | 20 | 2.71e-01 | -1.42e-01 | 6.44e-01 |
| Regulated proteolysis of p75NTR | 11 | 2.73e-01 | -1.91e-01 | 6.47e-01 |
| Metalloprotease DUBs | 16 | 2.73e-01 | 1.58e-01 | 6.47e-01 |
| ROS sensing by NFE2L2 | 54 | 2.73e-01 | 8.62e-02 | 6.47e-01 |
| PI Metabolism | 71 | 2.76e-01 | -7.48e-02 | 6.52e-01 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | 35 | 2.78e-01 | -1.06e-01 | 6.55e-01 |
| Nuclear Events (kinase and transcription factor activation) | 56 | 2.80e-01 | 8.35e-02 | 6.59e-01 |
| Cellular response to chemical stress | 145 | 2.82e-01 | 5.19e-02 | 6.62e-01 |
| RHO GTPases Activate ROCKs | 19 | 2.82e-01 | 1.43e-01 | 6.62e-01 |
| ATF4 activates genes in response to endoplasmic reticulum stress | 26 | 2.84e-01 | 1.21e-01 | 6.66e-01 |
| Long-term potentiation | 12 | 2.85e-01 | -1.78e-01 | 6.66e-01 |
| SHC-mediated cascade:FGFR3 | 10 | 2.85e-01 | -1.95e-01 | 6.66e-01 |
| Visual phototransduction | 68 | 2.90e-01 | -7.43e-02 | 6.76e-01 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer’s disease models | 20 | 2.91e-01 | 1.36e-01 | 6.76e-01 |
| Neurodegenerative Diseases | 20 | 2.91e-01 | 1.36e-01 | 6.76e-01 |
| Heme signaling | 42 | 2.92e-01 | 9.41e-02 | 6.76e-01 |
| Infectious disease | 637 | 2.92e-01 | 2.47e-02 | 6.76e-01 |
| Dual Incision in GG-NER | 41 | 2.95e-01 | 9.47e-02 | 6.80e-01 |
| DAP12 signaling | 21 | 2.97e-01 | -1.31e-01 | 6.84e-01 |
| Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | 49 | 2.99e-01 | 8.59e-02 | 6.84e-01 |
| p53-Independent DNA Damage Response | 49 | 2.99e-01 | 8.59e-02 | 6.84e-01 |
| p53-Independent G1/S DNA damage checkpoint | 49 | 2.99e-01 | 8.59e-02 | 6.84e-01 |
| Regulation of RUNX1 Expression and Activity | 17 | 2.99e-01 | 1.45e-01 | 6.84e-01 |
| Signaling by FGFR4 in disease | 11 | 3.00e-01 | -1.81e-01 | 6.84e-01 |
| Mitochondrial protein import | 61 | 3.00e-01 | -7.68e-02 | 6.84e-01 |
| Synthesis of bile acids and bile salts via 24-hydroxycholesterol | 14 | 3.00e-01 | -1.60e-01 | 6.84e-01 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | 20 | 3.01e-01 | -1.34e-01 | 6.84e-01 |
| NCAM1 interactions | 18 | 3.01e-01 | 1.41e-01 | 6.84e-01 |
| MET activates PTK2 signaling | 16 | 3.02e-01 | -1.49e-01 | 6.84e-01 |
| Signaling by ERBB4 | 42 | 3.03e-01 | -9.20e-02 | 6.85e-01 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | 73 | 3.07e-01 | 6.93e-02 | 6.93e-01 |
| Class B/2 (Secretin family receptors) | 39 | 3.08e-01 | 9.45e-02 | 6.94e-01 |
| RUNX2 regulates osteoblast differentiation | 16 | 3.09e-01 | -1.47e-01 | 6.94e-01 |
| Beta-catenin independent WNT signaling | 117 | 3.09e-01 | 5.45e-02 | 6.94e-01 |
| Oncogene Induced Senescence | 33 | 3.09e-01 | 1.02e-01 | 6.94e-01 |
| E3 ubiquitin ligases ubiquitinate target proteins | 44 | 3.10e-01 | 8.85e-02 | 6.95e-01 |
| Membrane Trafficking | 531 | 3.11e-01 | 2.58e-02 | 6.97e-01 |
| Downstream signaling of activated FGFR2 | 17 | 3.13e-01 | -1.41e-01 | 6.99e-01 |
| Negative regulation of the PI3K/AKT network | 74 | 3.13e-01 | 6.78e-02 | 7.00e-01 |
| Signaling by RAF1 mutants | 34 | 3.14e-01 | 9.97e-02 | 7.01e-01 |
| TBC/RABGAPs | 43 | 3.17e-01 | 8.82e-02 | 7.04e-01 |
| Downstream signaling of activated FGFR4 | 17 | 3.17e-01 | -1.40e-01 | 7.04e-01 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | 70 | 3.18e-01 | 6.90e-02 | 7.06e-01 |
| Purine ribonucleoside monophosphate biosynthesis | 11 | 3.19e-01 | -1.74e-01 | 7.06e-01 |
| Interferon Signaling | 147 | 3.23e-01 | 4.73e-02 | 7.14e-01 |
| Formation of the ternary complex, and subsequently, the 43S complex | 51 | 3.26e-01 | -7.96e-02 | 7.19e-01 |
| Tryptophan catabolism | 10 | 3.27e-01 | 1.79e-01 | 7.19e-01 |
| FGFR2 alternative splicing | 25 | 3.28e-01 | 1.13e-01 | 7.19e-01 |
| RUNX2 regulates bone development | 22 | 3.28e-01 | -1.20e-01 | 7.19e-01 |
| Branched-chain amino acid catabolism | 21 | 3.29e-01 | 1.23e-01 | 7.19e-01 |
| Regulation of RUNX3 expression and activity | 54 | 3.29e-01 | 7.69e-02 | 7.19e-01 |
| Class I MHC mediated antigen processing & presentation | 331 | 3.29e-01 | 3.13e-02 | 7.19e-01 |
| KSRP (KHSRP) binds and destabilizes mRNA | 17 | 3.29e-01 | -1.37e-01 | 7.19e-01 |
| Thrombin signalling through proteinase activated receptors (PARs) | 21 | 3.31e-01 | 1.23e-01 | 7.20e-01 |
| Glyoxylate metabolism and glycine degradation | 27 | 3.31e-01 | -1.08e-01 | 7.20e-01 |
| CD28 co-stimulation | 26 | 3.32e-01 | -1.10e-01 | 7.20e-01 |
| Regulation of IFNA signaling | 12 | 3.34e-01 | 1.61e-01 | 7.23e-01 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | 72 | 3.35e-01 | 6.58e-02 | 7.23e-01 |
| Molecules associated with elastic fibres | 19 | 3.35e-01 | 1.28e-01 | 7.23e-01 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | 64 | 3.35e-01 | 6.97e-02 | 7.23e-01 |
| HS-GAG biosynthesis | 22 | 3.41e-01 | 1.17e-01 | 7.29e-01 |
| Cytochrome c-mediated apoptotic response | 13 | 3.42e-01 | 1.52e-01 | 7.29e-01 |
| APC truncation mutants have impaired AXIN binding | 14 | 3.42e-01 | 1.47e-01 | 7.29e-01 |
| AXIN missense mutants destabilize the destruction complex | 14 | 3.42e-01 | 1.47e-01 | 7.29e-01 |
| Signaling by AMER1 mutants | 14 | 3.42e-01 | 1.47e-01 | 7.29e-01 |
| Signaling by APC mutants | 14 | 3.42e-01 | 1.47e-01 | 7.29e-01 |
| Signaling by AXIN mutants | 14 | 3.42e-01 | 1.47e-01 | 7.29e-01 |
| Truncations of AMER1 destabilize the destruction complex | 14 | 3.42e-01 | 1.47e-01 | 7.29e-01 |
| Nucleotide salvage | 20 | 3.44e-01 | 1.22e-01 | 7.32e-01 |
| Platelet calcium homeostasis | 15 | 3.45e-01 | 1.41e-01 | 7.33e-01 |
| RHOBTB GTPase Cycle | 33 | 3.47e-01 | 9.46e-02 | 7.37e-01 |
| Interleukin-2 family signaling | 29 | 3.48e-01 | 1.01e-01 | 7.37e-01 |
| L1CAM interactions | 72 | 3.49e-01 | 6.39e-02 | 7.37e-01 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | 11 | 3.49e-01 | 1.63e-01 | 7.37e-01 |
| Post-chaperonin tubulin folding pathway | 17 | 3.50e-01 | -1.31e-01 | 7.37e-01 |
| Mitophagy | 27 | 3.50e-01 | 1.04e-01 | 7.37e-01 |
| Prolactin receptor signaling | 11 | 3.51e-01 | -1.62e-01 | 7.38e-01 |
| Ion transport by P-type ATPases | 36 | 3.52e-01 | 8.97e-02 | 7.39e-01 |
| Sema3A PAK dependent Axon repulsion | 14 | 3.53e-01 | -1.43e-01 | 7.39e-01 |
| VxPx cargo-targeting to cilium | 18 | 3.53e-01 | -1.26e-01 | 7.40e-01 |
| Ras activation upon Ca2+ influx through NMDA receptor | 16 | 3.54e-01 | -1.34e-01 | 7.40e-01 |
| Asymmetric localization of PCP proteins | 58 | 3.55e-01 | 7.02e-02 | 7.41e-01 |
| Regulated Necrosis | 47 | 3.55e-01 | -7.80e-02 | 7.41e-01 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | 69 | 3.56e-01 | 6.43e-02 | 7.41e-01 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | 32 | 3.58e-01 | -9.40e-02 | 7.42e-01 |
| RUNX3 regulates p14-ARF | 10 | 3.59e-01 | 1.68e-01 | 7.42e-01 |
| Golgi Associated Vesicle Biogenesis | 55 | 3.60e-01 | 7.14e-02 | 7.42e-01 |
| PI-3K cascade:FGFR1 | 10 | 3.60e-01 | -1.67e-01 | 7.42e-01 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | 30 | 3.61e-01 | 9.64e-02 | 7.42e-01 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | 30 | 3.61e-01 | 9.64e-02 | 7.42e-01 |
| Phenylalanine and tyrosine metabolism | 10 | 3.61e-01 | 1.67e-01 | 7.42e-01 |
| Pyruvate metabolism and Citric Acid (TCA) cycle | 47 | 3.62e-01 | -7.69e-02 | 7.42e-01 |
| Chaperone Mediated Autophagy | 17 | 3.62e-01 | 1.28e-01 | 7.42e-01 |
| RAS processing | 17 | 3.63e-01 | 1.27e-01 | 7.42e-01 |
| PI-3K cascade:FGFR2 | 10 | 3.64e-01 | -1.66e-01 | 7.42e-01 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | 13 | 3.65e-01 | -1.45e-01 | 7.42e-01 |
| Centrosome maturation | 78 | 3.65e-01 | -5.94e-02 | 7.42e-01 |
| Recruitment of mitotic centrosome proteins and complexes | 78 | 3.65e-01 | -5.94e-02 | 7.42e-01 |
| PIP3 activates AKT signaling | 223 | 3.65e-01 | 3.53e-02 | 7.42e-01 |
| TNF signaling | 43 | 3.70e-01 | -7.91e-02 | 7.49e-01 |
| PI-3K cascade:FGFR4 | 10 | 3.70e-01 | -1.64e-01 | 7.49e-01 |
| MAP kinase activation | 61 | 3.70e-01 | 6.64e-02 | 7.49e-01 |
| N-glycan antennae elongation in the medial/trans-Golgi | 19 | 3.70e-01 | 1.19e-01 | 7.49e-01 |
| IKK complex recruitment mediated by RIP1 | 20 | 3.72e-01 | -1.15e-01 | 7.52e-01 |
| NRIF signals cell death from the nucleus | 15 | 3.73e-01 | -1.33e-01 | 7.52e-01 |
| Metabolism of RNA | 658 | 3.74e-01 | -2.05e-02 | 7.54e-01 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | 42 | 3.78e-01 | -7.86e-02 | 7.60e-01 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | 48 | 3.79e-01 | 7.34e-02 | 7.60e-01 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | 13 | 3.80e-01 | -1.41e-01 | 7.60e-01 |
| The role of Nef in HIV-1 replication and disease pathogenesis | 23 | 3.80e-01 | -1.06e-01 | 7.60e-01 |
| Detoxification of Reactive Oxygen Species | 28 | 3.81e-01 | -9.57e-02 | 7.62e-01 |
| MASTL Facilitates Mitotic Progression | 10 | 3.82e-01 | 1.60e-01 | 7.62e-01 |
| Degradation of AXIN | 52 | 3.85e-01 | 6.97e-02 | 7.67e-01 |
| Nucleotide catabolism | 28 | 3.86e-01 | 9.46e-02 | 7.69e-01 |
| VLDLR internalisation and degradation | 12 | 3.87e-01 | 1.44e-01 | 7.69e-01 |
| S33 mutants of beta-catenin aren’t phosphorylated | 15 | 3.91e-01 | 1.28e-01 | 7.70e-01 |
| S37 mutants of beta-catenin aren’t phosphorylated | 15 | 3.91e-01 | 1.28e-01 | 7.70e-01 |
| S45 mutants of beta-catenin aren’t phosphorylated | 15 | 3.91e-01 | 1.28e-01 | 7.70e-01 |
| Signaling by CTNNB1 phospho-site mutants | 15 | 3.91e-01 | 1.28e-01 | 7.70e-01 |
| Signaling by GSK3beta mutants | 15 | 3.91e-01 | 1.28e-01 | 7.70e-01 |
| T41 mutants of beta-catenin aren’t phosphorylated | 15 | 3.91e-01 | 1.28e-01 | 7.70e-01 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | 11 | 3.92e-01 | 1.49e-01 | 7.71e-01 |
| Interleukin-20 family signaling | 15 | 3.93e-01 | 1.27e-01 | 7.72e-01 |
| Nuclear import of Rev protein | 33 | 3.95e-01 | 8.56e-02 | 7.73e-01 |
| BMAL1:CLOCK,NPAS2 activates circadian gene expression | 25 | 3.95e-01 | 9.83e-02 | 7.73e-01 |
| Constitutive Signaling by AKT1 E17K in Cancer | 24 | 3.95e-01 | -1.00e-01 | 7.73e-01 |
| Interleukin-7 signaling | 16 | 3.98e-01 | 1.22e-01 | 7.77e-01 |
| Diseases associated with the TLR signaling cascade | 22 | 3.99e-01 | 1.04e-01 | 7.77e-01 |
| Diseases of Immune System | 22 | 3.99e-01 | 1.04e-01 | 7.77e-01 |
| Opioid Signalling | 60 | 4.00e-01 | -6.29e-02 | 7.77e-01 |
| Metabolism of folate and pterines | 16 | 4.01e-01 | 1.21e-01 | 7.79e-01 |
| Signaling by FGFR2 | 57 | 4.02e-01 | 6.42e-02 | 7.80e-01 |
| Signaling by FGFR | 69 | 4.03e-01 | 5.83e-02 | 7.80e-01 |
| activated TAK1 mediates p38 MAPK activation | 18 | 4.04e-01 | 1.14e-01 | 7.80e-01 |
| CDT1 association with the CDC6:ORC:origin complex | 56 | 4.05e-01 | 6.44e-02 | 7.82e-01 |
| Triglyceride biosynthesis | 10 | 4.06e-01 | 1.52e-01 | 7.82e-01 |
| Activation of G protein gated Potassium channels | 14 | 4.08e-01 | -1.28e-01 | 7.83e-01 |
| G protein gated Potassium channels | 14 | 4.08e-01 | -1.28e-01 | 7.83e-01 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | 14 | 4.08e-01 | -1.28e-01 | 7.83e-01 |
| Sensory Perception | 134 | 4.09e-01 | -4.14e-02 | 7.83e-01 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | 16 | 4.09e-01 | -1.19e-01 | 7.83e-01 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | 16 | 4.09e-01 | -1.19e-01 | 7.83e-01 |
| IL-6-type cytokine receptor ligand interactions | 13 | 4.11e-01 | 1.32e-01 | 7.84e-01 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | 25 | 4.12e-01 | 9.48e-02 | 7.85e-01 |
| Deactivation of the beta-catenin transactivating complex | 38 | 4.13e-01 | -7.69e-02 | 7.85e-01 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | 23 | 4.14e-01 | 9.85e-02 | 7.85e-01 |
| RHOH GTPase cycle | 32 | 4.15e-01 | 8.34e-02 | 7.85e-01 |
| Disorders of Developmental Biology | 12 | 4.15e-01 | -1.36e-01 | 7.85e-01 |
| Disorders of Nervous System Development | 12 | 4.15e-01 | -1.36e-01 | 7.85e-01 |
| Loss of function of MECP2 in Rett syndrome | 12 | 4.15e-01 | -1.36e-01 | 7.85e-01 |
| Pervasive developmental disorders | 12 | 4.15e-01 | -1.36e-01 | 7.85e-01 |
| Interleukin-35 Signalling | 10 | 4.17e-01 | 1.48e-01 | 7.86e-01 |
| Ion homeostasis | 35 | 4.18e-01 | 7.91e-02 | 7.87e-01 |
| G2/M DNA damage checkpoint | 60 | 4.19e-01 | 6.04e-02 | 7.88e-01 |
| Folding of actin by CCT/TriC | 10 | 4.20e-01 | 1.47e-01 | 7.88e-01 |
| Cell surface interactions at the vascular wall | 86 | 4.23e-01 | 5.01e-02 | 7.93e-01 |
| EPHB-mediated forward signaling | 34 | 4.25e-01 | -7.91e-02 | 7.96e-01 |
| Formation of the beta-catenin:TCF transactivating complex | 30 | 4.28e-01 | 8.37e-02 | 7.99e-01 |
| Diseases of carbohydrate metabolism | 29 | 4.28e-01 | 8.51e-02 | 7.99e-01 |
| Syndecan interactions | 17 | 4.29e-01 | 1.11e-01 | 8.00e-01 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | 61 | 4.32e-01 | 5.82e-02 | 8.05e-01 |
| Cross-presentation of soluble exogenous antigens (endosomes) | 42 | 4.34e-01 | 6.99e-02 | 8.06e-01 |
| mTORC1-mediated signalling | 24 | 4.34e-01 | 9.23e-02 | 8.06e-01 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | 47 | 4.35e-01 | 6.59e-02 | 8.07e-01 |
| RNA Polymerase II Transcription Termination | 65 | 4.36e-01 | -5.59e-02 | 8.08e-01 |
| Synthesis of IP2, IP, and Ins in the cytosol | 12 | 4.37e-01 | 1.30e-01 | 8.09e-01 |
| GPVI-mediated activation cascade | 22 | 4.41e-01 | -9.50e-02 | 8.13e-01 |
| PTEN Regulation | 134 | 4.41e-01 | 3.86e-02 | 8.13e-01 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | 35 | 4.41e-01 | 7.53e-02 | 8.13e-01 |
| TP53 Regulates Transcription of DNA Repair Genes | 61 | 4.42e-01 | 5.69e-02 | 8.14e-01 |
| Glutamate Neurotransmitter Release Cycle | 17 | 4.43e-01 | 1.07e-01 | 8.15e-01 |
| Glutathione synthesis and recycling | 12 | 4.44e-01 | 1.28e-01 | 8.15e-01 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | 57 | 4.46e-01 | 5.84e-02 | 8.17e-01 |
| Fatty acyl-CoA biosynthesis | 29 | 4.47e-01 | 8.17e-02 | 8.18e-01 |
| Ub-specific processing proteases | 150 | 4.49e-01 | 3.59e-02 | 8.20e-01 |
| ERK/MAPK targets | 21 | 4.51e-01 | 9.50e-02 | 8.22e-01 |
| RET signaling | 34 | 4.51e-01 | -7.47e-02 | 8.22e-01 |
| DNA Damage/Telomere Stress Induced Senescence | 28 | 4.52e-01 | 8.21e-02 | 8.22e-01 |
| SLBP independent Processing of Histone Pre-mRNAs | 10 | 4.53e-01 | -1.37e-01 | 8.22e-01 |
| Attenuation phase | 21 | 4.53e-01 | 9.47e-02 | 8.22e-01 |
| Diseases of programmed cell death | 41 | 4.54e-01 | 6.77e-02 | 8.23e-01 |
| Negative regulation of MET activity | 18 | 4.57e-01 | 1.01e-01 | 8.26e-01 |
| Transcriptional regulation by RUNX2 | 96 | 4.58e-01 | 4.39e-02 | 8.26e-01 |
| Regulation of TP53 Degradation | 34 | 4.58e-01 | -7.35e-02 | 8.26e-01 |
| Regulation of TP53 Expression and Degradation | 34 | 4.58e-01 | -7.35e-02 | 8.26e-01 |
| Interleukin-17 signaling | 65 | 4.58e-01 | 5.32e-02 | 8.26e-01 |
| Inhibition of DNA recombination at telomere | 21 | 4.59e-01 | 9.33e-02 | 8.26e-01 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | 17 | 4.59e-01 | -1.04e-01 | 8.26e-01 |
| Signaling by FGFR in disease | 49 | 4.60e-01 | 6.11e-02 | 8.26e-01 |
| TRAF6 mediated IRF7 activation | 15 | 4.61e-01 | -1.10e-01 | 8.26e-01 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | 52 | 4.65e-01 | 5.86e-02 | 8.30e-01 |
| Frs2-mediated activation | 10 | 4.67e-01 | 1.33e-01 | 8.30e-01 |
| Regulation of BACH1 activity | 11 | 4.67e-01 | 1.27e-01 | 8.30e-01 |
| Switching of origins to a post-replicative state | 87 | 4.67e-01 | 4.51e-02 | 8.30e-01 |
| Interleukin-27 signaling | 10 | 4.68e-01 | 1.33e-01 | 8.30e-01 |
| Downstream TCR signaling | 76 | 4.69e-01 | 4.81e-02 | 8.30e-01 |
| tRNA processing | 114 | 4.69e-01 | -3.93e-02 | 8.30e-01 |
| NGF-stimulated transcription | 35 | 4.69e-01 | 7.08e-02 | 8.30e-01 |
| Signaling by FGFR2 IIIa TM | 17 | 4.70e-01 | 1.01e-01 | 8.30e-01 |
| NEP/NS2 Interacts with the Cellular Export Machinery | 31 | 4.70e-01 | 7.50e-02 | 8.30e-01 |
| Platelet Aggregation (Plug Formation) | 24 | 4.71e-01 | 8.51e-02 | 8.30e-01 |
| Fanconi Anemia Pathway | 36 | 4.71e-01 | 6.95e-02 | 8.30e-01 |
| SHC1 events in EGFR signaling | 11 | 4.71e-01 | 1.26e-01 | 8.30e-01 |
| MAPK6/MAPK4 signaling | 79 | 4.71e-01 | 4.69e-02 | 8.30e-01 |
| TRAF3-dependent IRF activation pathway | 13 | 4.73e-01 | -1.15e-01 | 8.30e-01 |
| SUMOylation of DNA methylation proteins | 16 | 4.73e-01 | 1.04e-01 | 8.30e-01 |
| G-protein beta:gamma signalling | 17 | 4.73e-01 | -1.00e-01 | 8.30e-01 |
| RA biosynthesis pathway | 15 | 4.75e-01 | 1.06e-01 | 8.32e-01 |
| HATs acetylate histones | 78 | 4.76e-01 | 4.67e-02 | 8.32e-01 |
| Serotonin Neurotransmitter Release Cycle | 10 | 4.76e-01 | 1.30e-01 | 8.32e-01 |
| STING mediated induction of host immune responses | 10 | 4.78e-01 | -1.30e-01 | 8.34e-01 |
| Heme degradation | 14 | 4.79e-01 | 1.09e-01 | 8.35e-01 |
| Transcription of E2F targets under negative control by DREAM complex | 19 | 4.82e-01 | 9.31e-02 | 8.40e-01 |
| RHO GTPases activate IQGAPs | 11 | 4.85e-01 | 1.22e-01 | 8.43e-01 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | 63 | 4.85e-01 | 5.09e-02 | 8.43e-01 |
| TP53 Regulates Transcription of Cell Cycle Genes | 47 | 4.87e-01 | 5.86e-02 | 8.43e-01 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | 25 | 4.87e-01 | -8.03e-02 | 8.43e-01 |
| Caspase activation via extrinsic apoptotic signalling pathway | 21 | 4.88e-01 | 8.74e-02 | 8.43e-01 |
| Cyclin D associated events in G1 | 46 | 4.89e-01 | -5.90e-02 | 8.43e-01 |
| G1 Phase | 46 | 4.89e-01 | -5.90e-02 | 8.43e-01 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | 64 | 4.89e-01 | 5.00e-02 | 8.43e-01 |
| Regulation of beta-cell development | 27 | 4.90e-01 | 7.68e-02 | 8.43e-01 |
| Mitochondrial iron-sulfur cluster biogenesis | 13 | 4.90e-01 | -1.11e-01 | 8.43e-01 |
| Metabolism of nitric oxide: NOS3 activation and regulation | 13 | 4.92e-01 | 1.10e-01 | 8.44e-01 |
| Protein-protein interactions at synapses | 52 | 4.94e-01 | 5.49e-02 | 8.46e-01 |
| RNA Polymerase II Pre-transcription Events | 78 | 4.94e-01 | -4.48e-02 | 8.46e-01 |
| Cellular response to hypoxia | 72 | 4.96e-01 | 4.64e-02 | 8.49e-01 |
| Spry regulation of FGF signaling | 16 | 4.97e-01 | 9.81e-02 | 8.49e-01 |
| Nicotinamide salvaging | 14 | 4.98e-01 | -1.05e-01 | 8.49e-01 |
| Signaling by MET | 63 | 4.99e-01 | -4.92e-02 | 8.51e-01 |
| Signaling by FGFR1 in disease | 30 | 5.01e-01 | 7.11e-02 | 8.52e-01 |
| Cytosolic iron-sulfur cluster assembly | 11 | 5.01e-01 | -1.17e-01 | 8.52e-01 |
| TNFR1-induced NFkappaB signaling pathway | 25 | 5.02e-01 | -7.75e-02 | 8.52e-01 |
| Nuclear signaling by ERBB4 | 21 | 5.03e-01 | -8.45e-02 | 8.52e-01 |
| TCR signaling | 91 | 5.03e-01 | 4.07e-02 | 8.52e-01 |
| Budding and maturation of HIV virion | 28 | 5.04e-01 | -7.30e-02 | 8.53e-01 |
| Transcriptional regulation of white adipocyte differentiation | 74 | 5.05e-01 | 4.49e-02 | 8.53e-01 |
| ALK mutants bind TKIs | 10 | 5.05e-01 | 1.22e-01 | 8.53e-01 |
| N-Glycan antennae elongation | 12 | 5.07e-01 | 1.11e-01 | 8.55e-01 |
| mRNA decay by 5’ to 3’ exoribonuclease | 15 | 5.09e-01 | 9.86e-02 | 8.56e-01 |
| Neurexins and neuroligins | 36 | 5.10e-01 | 6.35e-02 | 8.57e-01 |
| Degradation of DVL | 53 | 5.11e-01 | 5.22e-02 | 8.58e-01 |
| VEGFR2 mediated vascular permeability | 22 | 5.12e-01 | -8.08e-02 | 8.58e-01 |
| Formation of TC-NER Pre-Incision Complex | 53 | 5.12e-01 | -5.20e-02 | 8.58e-01 |
| Ubiquitin-dependent degradation of Cyclin D | 49 | 5.13e-01 | 5.40e-02 | 8.58e-01 |
| Methylation | 12 | 5.14e-01 | 1.09e-01 | 8.59e-01 |
| Signaling by NOTCH2 | 24 | 5.15e-01 | 7.68e-02 | 8.59e-01 |
| Viral Messenger RNA Synthesis | 43 | 5.17e-01 | 5.71e-02 | 8.62e-01 |
| Signaling by NTRK3 (TRKC) | 14 | 5.17e-01 | -9.99e-02 | 8.62e-01 |
| Regulation of innate immune responses to cytosolic DNA | 11 | 5.20e-01 | 1.12e-01 | 8.64e-01 |
| Regulation of TNFR1 signaling | 34 | 5.21e-01 | -6.37e-02 | 8.65e-01 |
| G beta:gamma signalling through CDC42 | 11 | 5.23e-01 | -1.11e-01 | 8.66e-01 |
| TRP channels | 10 | 5.23e-01 | -1.17e-01 | 8.66e-01 |
| Deadenylation of mRNA | 24 | 5.24e-01 | 7.52e-02 | 8.66e-01 |
| Regulation of insulin secretion | 47 | 5.24e-01 | -5.37e-02 | 8.66e-01 |
| Signaling by GPCR | 289 | 5.25e-01 | 2.18e-02 | 8.66e-01 |
| SUMOylation of RNA binding proteins | 46 | 5.25e-01 | 5.41e-02 | 8.66e-01 |
| Platelet homeostasis | 48 | 5.26e-01 | 5.29e-02 | 8.67e-01 |
| Mitochondrial calcium ion transport | 21 | 5.28e-01 | -7.95e-02 | 8.68e-01 |
| Glycogen metabolism | 25 | 5.29e-01 | -7.28e-02 | 8.68e-01 |
| Translation | 270 | 5.29e-01 | -2.24e-02 | 8.68e-01 |
| MAPK targets/ Nuclear events mediated by MAP kinases | 30 | 5.30e-01 | 6.62e-02 | 8.69e-01 |
| TNFR1-induced proapoptotic signaling | 12 | 5.31e-01 | -1.04e-01 | 8.70e-01 |
| Telomere Extension By Telomerase | 22 | 5.33e-01 | 7.69e-02 | 8.70e-01 |
| PECAM1 interactions | 11 | 5.33e-01 | -1.09e-01 | 8.70e-01 |
| Senescence-Associated Secretory Phenotype (SASP) | 49 | 5.35e-01 | -5.13e-02 | 8.72e-01 |
| Activation of NF-kappaB in B cells | 62 | 5.35e-01 | 4.56e-02 | 8.72e-01 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | 68 | 5.36e-01 | 4.34e-02 | 8.73e-01 |
| Influenza Infection | 151 | 5.37e-01 | -2.92e-02 | 8.73e-01 |
| Metabolism of steroid hormones | 23 | 5.39e-01 | -7.40e-02 | 8.74e-01 |
| WNT5A-dependent internalization of FZD4 | 12 | 5.39e-01 | 1.02e-01 | 8.74e-01 |
| Nonhomologous End-Joining (NHEJ) | 34 | 5.41e-01 | 6.07e-02 | 8.76e-01 |
| NS1 Mediated Effects on Host Pathways | 39 | 5.42e-01 | 5.64e-02 | 8.77e-01 |
| CRMPs in Sema3A signaling | 12 | 5.44e-01 | -1.01e-01 | 8.79e-01 |
| mRNA 3’-end processing | 56 | 5.47e-01 | -4.66e-02 | 8.82e-01 |
| Cellular Senescence | 124 | 5.48e-01 | 3.13e-02 | 8.84e-01 |
| IRS-mediated signalling | 32 | 5.49e-01 | -6.13e-02 | 8.84e-01 |
| Nervous system development | 444 | 5.51e-01 | 1.66e-02 | 8.86e-01 |
| Downstream signaling of activated FGFR1 | 20 | 5.51e-01 | -7.70e-02 | 8.86e-01 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | 86 | 5.54e-01 | 3.69e-02 | 8.89e-01 |
| Triglyceride metabolism | 22 | 5.55e-01 | 7.28e-02 | 8.89e-01 |
| Metabolism of porphyrins | 25 | 5.55e-01 | 6.81e-02 | 8.89e-01 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | 16 | 5.59e-01 | 8.44e-02 | 8.94e-01 |
| Signaling by PDGFRA extracellular domain mutants | 11 | 5.61e-01 | -1.01e-01 | 8.95e-01 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | 11 | 5.61e-01 | -1.01e-01 | 8.95e-01 |
| Regulation of PTEN stability and activity | 64 | 5.63e-01 | 4.19e-02 | 8.95e-01 |
| Formation of apoptosome | 11 | 5.64e-01 | 1.00e-01 | 8.95e-01 |
| Regulation of the apoptosome activity | 11 | 5.64e-01 | 1.00e-01 | 8.95e-01 |
| Neddylation | 214 | 5.65e-01 | -2.29e-02 | 8.95e-01 |
| Incretin synthesis, secretion, and inactivation | 13 | 5.65e-01 | 9.22e-02 | 8.95e-01 |
| MET activates RAP1 and RAC1 | 10 | 5.65e-01 | -1.05e-01 | 8.95e-01 |
| Cilium Assembly | 172 | 5.67e-01 | 2.53e-02 | 8.97e-01 |
| FLT3 Signaling | 32 | 5.69e-01 | 5.82e-02 | 8.97e-01 |
| Reproduction | 56 | 5.70e-01 | 4.39e-02 | 8.97e-01 |
| Synthesis of PIPs at the late endosome membrane | 10 | 5.71e-01 | -1.04e-01 | 8.97e-01 |
| Cargo trafficking to the periciliary membrane | 47 | 5.71e-01 | 4.78e-02 | 8.97e-01 |
| EPHA-mediated growth cone collapse | 15 | 5.71e-01 | 8.45e-02 | 8.97e-01 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | 17 | 5.71e-01 | 7.93e-02 | 8.97e-01 |
| Synthesis of PIPs at the Golgi membrane | 15 | 5.72e-01 | -8.44e-02 | 8.97e-01 |
| Plasma lipoprotein assembly | 17 | 5.73e-01 | -7.90e-02 | 8.97e-01 |
| Activation of BH3-only proteins | 28 | 5.74e-01 | -6.14e-02 | 8.97e-01 |
| Biotin transport and metabolism | 11 | 5.75e-01 | 9.77e-02 | 8.97e-01 |
| mRNA Capping | 29 | 5.75e-01 | 6.02e-02 | 8.97e-01 |
| Deadenylation-dependent mRNA decay | 55 | 5.75e-01 | 4.38e-02 | 8.97e-01 |
| GPCR downstream signalling | 257 | 5.75e-01 | 2.04e-02 | 8.97e-01 |
| Pregnenolone biosynthesis | 10 | 5.77e-01 | -1.02e-01 | 8.97e-01 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | 31 | 5.77e-01 | -5.79e-02 | 8.97e-01 |
| RHO GTPases activate PKNs | 31 | 5.77e-01 | -5.78e-02 | 8.97e-01 |
| Export of Viral Ribonucleoproteins from Nucleus | 32 | 5.78e-01 | 5.69e-02 | 8.97e-01 |
| Extra-nuclear estrogen signaling | 57 | 5.79e-01 | -4.25e-02 | 8.98e-01 |
| Glucagon-type ligand receptors | 11 | 5.80e-01 | -9.64e-02 | 8.98e-01 |
| Clathrin-mediated endocytosis | 116 | 5.82e-01 | 2.97e-02 | 9.00e-01 |
| Prostacyclin signalling through prostacyclin receptor | 10 | 5.86e-01 | -9.95e-02 | 9.05e-01 |
| Synthesis of PE | 12 | 5.87e-01 | 9.07e-02 | 9.06e-01 |
| Hyaluronan metabolism | 13 | 5.87e-01 | 8.69e-02 | 9.06e-01 |
| Trafficking of GluR2-containing AMPA receptors | 10 | 5.88e-01 | -9.88e-02 | 9.06e-01 |
| Fcgamma receptor (FCGR) dependent phagocytosis | 70 | 5.90e-01 | 3.73e-02 | 9.07e-01 |
| Regulation of Apoptosis | 50 | 5.91e-01 | 4.40e-02 | 9.07e-01 |
| Diseases associated with N-glycosylation of proteins | 17 | 5.91e-01 | 7.53e-02 | 9.07e-01 |
| Constitutive Signaling by Aberrant PI3K in Cancer | 43 | 5.92e-01 | 4.72e-02 | 9.07e-01 |
| EPH-Ephrin signaling | 80 | 5.93e-01 | 3.46e-02 | 9.07e-01 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | 27 | 5.94e-01 | 5.94e-02 | 9.07e-01 |
| Inwardly rectifying K+ channels | 17 | 5.95e-01 | -7.44e-02 | 9.07e-01 |
| MECP2 regulates neuronal receptors and channels | 13 | 5.96e-01 | -8.50e-02 | 9.07e-01 |
| Muscle contraction | 106 | 5.96e-01 | 2.99e-02 | 9.07e-01 |
| PIWI-interacting RNA (piRNA) biogenesis | 18 | 5.96e-01 | 7.21e-02 | 9.07e-01 |
| Inositol phosphate metabolism | 37 | 5.97e-01 | 5.03e-02 | 9.07e-01 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | 17 | 5.97e-01 | 7.41e-02 | 9.07e-01 |
| Defective Intrinsic Pathway for Apoptosis | 23 | 5.99e-01 | 6.33e-02 | 9.08e-01 |
| Non-integrin membrane-ECM interactions | 37 | 6.00e-01 | -4.99e-02 | 9.08e-01 |
| Keratan sulfate/keratin metabolism | 25 | 6.01e-01 | 6.05e-02 | 9.08e-01 |
| Aggrephagy | 20 | 6.01e-01 | 6.76e-02 | 9.08e-01 |
| Transcriptional regulation of pluripotent stem cells | 21 | 6.01e-01 | 6.60e-02 | 9.08e-01 |
| Bile acid and bile salt metabolism | 38 | 6.03e-01 | 4.87e-02 | 9.10e-01 |
| RHOBTB2 GTPase cycle | 23 | 6.04e-01 | 6.25e-02 | 9.10e-01 |
| G beta:gamma signalling through PI3Kgamma | 13 | 6.06e-01 | -8.28e-02 | 9.10e-01 |
| APC/C:Cdc20 mediated degradation of Securin | 65 | 6.06e-01 | 3.70e-02 | 9.10e-01 |
| Activation of GABAB receptors | 23 | 6.07e-01 | -6.19e-02 | 9.10e-01 |
| GABA B receptor activation | 23 | 6.07e-01 | -6.19e-02 | 9.10e-01 |
| SUMOylation of chromatin organization proteins | 55 | 6.07e-01 | -4.01e-02 | 9.10e-01 |
| Energy dependent regulation of mTOR by LKB1-AMPK | 28 | 6.08e-01 | -5.61e-02 | 9.10e-01 |
| Dopamine Neurotransmitter Release Cycle | 14 | 6.10e-01 | 7.87e-02 | 9.13e-01 |
| Gastrin-CREB signalling pathway via PKC and MAPK | 16 | 6.15e-01 | -7.27e-02 | 9.16e-01 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | 23 | 6.18e-01 | -6.00e-02 | 9.16e-01 |
| Signaling by Non-Receptor Tyrosine Kinases | 44 | 6.19e-01 | 4.33e-02 | 9.16e-01 |
| Signaling by PTK6 | 44 | 6.19e-01 | 4.33e-02 | 9.16e-01 |
| DNA Damage Recognition in GG-NER | 38 | 6.20e-01 | 4.65e-02 | 9.16e-01 |
| Recruitment of NuMA to mitotic centrosomes | 77 | 6.20e-01 | -3.27e-02 | 9.16e-01 |
| SUMOylation of immune response proteins | 11 | 6.20e-01 | -8.63e-02 | 9.16e-01 |
| Negative regulation of FGFR4 signaling | 21 | 6.21e-01 | 6.24e-02 | 9.16e-01 |
| Cell-cell junction organization | 42 | 6.21e-01 | 4.41e-02 | 9.16e-01 |
| Caspase activation via Death Receptors in the presence of ligand | 13 | 6.22e-01 | -7.91e-02 | 9.16e-01 |
| Apoptotic factor-mediated response | 18 | 6.22e-01 | 6.72e-02 | 9.16e-01 |
| Signaling by WNT | 213 | 6.23e-01 | 1.96e-02 | 9.16e-01 |
| Class I peroxisomal membrane protein import | 19 | 6.25e-01 | -6.48e-02 | 9.16e-01 |
| Negative regulation of FGFR2 signaling | 21 | 6.26e-01 | 6.14e-02 | 9.16e-01 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | 49 | 6.26e-01 | -4.02e-02 | 9.16e-01 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | 49 | 6.26e-01 | -4.02e-02 | 9.16e-01 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | 49 | 6.26e-01 | -4.02e-02 | 9.16e-01 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | 49 | 6.26e-01 | -4.02e-02 | 9.16e-01 |
| Signaling by NOTCH1 in Cancer | 49 | 6.26e-01 | -4.02e-02 | 9.16e-01 |
| Downstream signaling events of B Cell Receptor (BCR) | 74 | 6.26e-01 | 3.28e-02 | 9.16e-01 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | 27 | 6.27e-01 | -5.41e-02 | 9.16e-01 |
| Hedgehog ‘off’ state | 86 | 6.28e-01 | -3.03e-02 | 9.16e-01 |
| Nephrin family interactions | 17 | 6.28e-01 | 6.79e-02 | 9.16e-01 |
| Integrin signaling | 21 | 6.28e-01 | 6.10e-02 | 9.16e-01 |
| Vif-mediated degradation of APOBEC3G | 51 | 6.31e-01 | 3.89e-02 | 9.17e-01 |
| Formation of RNA Pol II elongation complex | 57 | 6.32e-01 | -3.67e-02 | 9.17e-01 |
| RNA Polymerase II Transcription Elongation | 57 | 6.32e-01 | -3.67e-02 | 9.17e-01 |
| Chromatin modifying enzymes | 195 | 6.32e-01 | 1.99e-02 | 9.17e-01 |
| Chromatin organization | 195 | 6.32e-01 | 1.99e-02 | 9.17e-01 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | 19 | 6.33e-01 | -6.32e-02 | 9.18e-01 |
| FCERI mediated NF-kB activation | 70 | 6.35e-01 | 3.28e-02 | 9.19e-01 |
| Meiotic synapsis | 26 | 6.40e-01 | 5.30e-02 | 9.23e-01 |
| Interactions of Rev with host cellular proteins | 36 | 6.41e-01 | 4.50e-02 | 9.23e-01 |
| Processing and activation of SUMO | 10 | 6.41e-01 | -8.51e-02 | 9.23e-01 |
| Xenobiotics | 15 | 6.41e-01 | -6.95e-02 | 9.23e-01 |
| RHO GTPases activate PAKs | 20 | 6.42e-01 | -6.01e-02 | 9.23e-01 |
| Regulation of pyruvate dehydrogenase (PDH) complex | 15 | 6.42e-01 | -6.93e-02 | 9.23e-01 |
| Integration of energy metabolism | 73 | 6.42e-01 | -3.15e-02 | 9.23e-01 |
| Recycling pathway of L1 | 24 | 6.43e-01 | 5.47e-02 | 9.23e-01 |
| Ephrin signaling | 15 | 6.44e-01 | -6.90e-02 | 9.23e-01 |
| G alpha (12/13) signalling events | 59 | 6.44e-01 | 3.48e-02 | 9.23e-01 |
| GABA receptor activation | 29 | 6.44e-01 | -4.95e-02 | 9.23e-01 |
| rRNA processing in the mitochondrion | 21 | 6.45e-01 | 5.80e-02 | 9.23e-01 |
| Signaling by ALK fusions and activated point mutants | 50 | 6.48e-01 | 3.74e-02 | 9.24e-01 |
| Signaling by ALK in cancer | 50 | 6.48e-01 | 3.74e-02 | 9.24e-01 |
| Signaling by FGFR3 | 32 | 6.50e-01 | -4.63e-02 | 9.25e-01 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | 20 | 6.53e-01 | 5.81e-02 | 9.25e-01 |
| NCAM signaling for neurite out-growth | 35 | 6.53e-01 | 4.39e-02 | 9.25e-01 |
| Adrenaline,noradrenaline inhibits insulin secretion | 15 | 6.53e-01 | 6.70e-02 | 9.25e-01 |
| Signalling to RAS | 18 | 6.53e-01 | 6.12e-02 | 9.25e-01 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | 18 | 6.55e-01 | -6.09e-02 | 9.25e-01 |
| Metabolism of amino acids and derivatives | 315 | 6.55e-01 | 1.47e-02 | 9.25e-01 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | 11 | 6.55e-01 | -7.77e-02 | 9.25e-01 |
| HS-GAG degradation | 18 | 6.56e-01 | -6.07e-02 | 9.25e-01 |
| RNA Pol II CTD phosphorylation and interaction with CE | 27 | 6.57e-01 | 4.93e-02 | 9.25e-01 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | 27 | 6.57e-01 | 4.93e-02 | 9.25e-01 |
| Signaling by Leptin | 10 | 6.58e-01 | 8.08e-02 | 9.25e-01 |
| Cytosolic sensors of pathogen-associated DNA | 53 | 6.59e-01 | 3.51e-02 | 9.25e-01 |
| Netrin-1 signaling | 35 | 6.59e-01 | -4.31e-02 | 9.25e-01 |
| NOD1/2 Signaling Pathway | 31 | 6.60e-01 | 4.57e-02 | 9.25e-01 |
| Vpu mediated degradation of CD4 | 49 | 6.61e-01 | 3.63e-02 | 9.25e-01 |
| CASP8 activity is inhibited | 10 | 6.61e-01 | -8.01e-02 | 9.25e-01 |
| Dimerization of procaspase-8 | 10 | 6.61e-01 | -8.01e-02 | 9.25e-01 |
| Regulation by c-FLIP | 10 | 6.61e-01 | -8.01e-02 | 9.25e-01 |
| Synthesis of IP3 and IP4 in the cytosol | 20 | 6.62e-01 | 5.64e-02 | 9.26e-01 |
| Inactivation of CSF3 (G-CSF) signaling | 22 | 6.65e-01 | 5.33e-02 | 9.29e-01 |
| Nuclear events stimulated by ALK signaling in cancer | 17 | 6.66e-01 | 6.05e-02 | 9.29e-01 |
| Negative regulation of FGFR1 signaling | 22 | 6.68e-01 | 5.29e-02 | 9.30e-01 |
| Post-translational modification: synthesis of GPI-anchored proteins | 48 | 6.70e-01 | -3.55e-02 | 9.33e-01 |
| Metabolic disorders of biological oxidation enzymes | 27 | 6.71e-01 | -4.73e-02 | 9.33e-01 |
| Regulation of gene expression by Hypoxia-inducible Factor | 11 | 6.71e-01 | 7.39e-02 | 9.33e-01 |
| Repression of WNT target genes | 12 | 6.72e-01 | 7.06e-02 | 9.33e-01 |
| A tetrasaccharide linker sequence is required for GAG synthesis | 18 | 6.73e-01 | 5.75e-02 | 9.33e-01 |
| G alpha (i) signalling events | 121 | 6.74e-01 | 2.22e-02 | 9.33e-01 |
| WNT ligand biogenesis and trafficking | 11 | 6.75e-01 | -7.30e-02 | 9.33e-01 |
| Assembly of the ORC complex at the origin of replication | 10 | 6.76e-01 | 7.64e-02 | 9.33e-01 |
| Interaction between L1 and Ankyrins | 15 | 6.76e-01 | -6.23e-02 | 9.33e-01 |
| Signal regulatory protein family interactions | 10 | 6.76e-01 | 7.62e-02 | 9.33e-01 |
| SRP-dependent cotranslational protein targeting to membrane | 109 | 6.80e-01 | 2.29e-02 | 9.36e-01 |
| RIP-mediated NFkB activation via ZBP1 | 14 | 6.80e-01 | 6.36e-02 | 9.36e-01 |
| PINK1-PRKN Mediated Mitophagy | 20 | 6.81e-01 | 5.32e-02 | 9.36e-01 |
| Dectin-1 mediated noncanonical NF-kB signaling | 58 | 6.83e-01 | -3.10e-02 | 9.39e-01 |
| Negative epigenetic regulation of rRNA expression | 47 | 6.84e-01 | 3.43e-02 | 9.40e-01 |
| Host Interactions of HIV factors | 122 | 6.85e-01 | 2.13e-02 | 9.40e-01 |
| RAB geranylgeranylation | 52 | 6.87e-01 | 3.23e-02 | 9.40e-01 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | 10 | 6.88e-01 | -7.34e-02 | 9.40e-01 |
| Signaling by ALK | 20 | 6.89e-01 | 5.18e-02 | 9.40e-01 |
| RNA polymerase II transcribes snRNA genes | 71 | 6.89e-01 | -2.75e-02 | 9.40e-01 |
| Membrane binding and targetting of GAG proteins | 14 | 6.90e-01 | -6.16e-02 | 9.40e-01 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | 14 | 6.90e-01 | -6.16e-02 | 9.40e-01 |
| Regulation of ornithine decarboxylase (ODC) | 48 | 6.92e-01 | 3.31e-02 | 9.40e-01 |
| AKT phosphorylates targets in the cytosol | 13 | 6.92e-01 | 6.35e-02 | 9.40e-01 |
| CLEC7A (Dectin-1) induces NFAT activation | 10 | 6.92e-01 | 7.24e-02 | 9.40e-01 |
| Signaling by TGFB family members | 87 | 6.92e-01 | 2.46e-02 | 9.40e-01 |
| Signaling by FGFR2 in disease | 30 | 6.94e-01 | -4.15e-02 | 9.42e-01 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | 29 | 6.96e-01 | -4.20e-02 | 9.42e-01 |
| Nucleotide biosynthesis | 14 | 6.96e-01 | -6.03e-02 | 9.42e-01 |
| Intraflagellar transport | 34 | 6.98e-01 | 3.85e-02 | 9.43e-01 |
| O-linked glycosylation of mucins | 34 | 6.99e-01 | 3.83e-02 | 9.44e-01 |
| Intracellular signaling by second messengers | 252 | 6.99e-01 | 1.42e-02 | 9.44e-01 |
| Myogenesis | 19 | 7.02e-01 | -5.07e-02 | 9.47e-01 |
| mRNA decay by 3’ to 5’ exoribonuclease | 16 | 7.03e-01 | -5.52e-02 | 9.47e-01 |
| G alpha (q) signalling events | 93 | 7.05e-01 | -2.27e-02 | 9.49e-01 |
| Regulation of signaling by CBL | 14 | 7.06e-01 | -5.82e-02 | 9.50e-01 |
| APC/C:Cdc20 mediated degradation of Cyclin B | 24 | 7.09e-01 | -4.41e-02 | 9.52e-01 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | 18 | 7.10e-01 | 5.06e-02 | 9.53e-01 |
| Nucleotide Excision Repair | 110 | 7.11e-01 | -2.04e-02 | 9.54e-01 |
| Insulin receptor signalling cascade | 37 | 7.12e-01 | 3.51e-02 | 9.54e-01 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | 11 | 7.15e-01 | -6.36e-02 | 9.54e-01 |
| Diseases of hemostasis | 11 | 7.15e-01 | -6.36e-02 | 9.54e-01 |
| Phosphorylation of the APC/C | 20 | 7.16e-01 | -4.71e-02 | 9.54e-01 |
| Pexophagy | 11 | 7.17e-01 | 6.31e-02 | 9.54e-01 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | 23 | 7.18e-01 | 4.35e-02 | 9.54e-01 |
| Metabolism of polyamines | 56 | 7.18e-01 | 2.79e-02 | 9.54e-01 |
| NoRC negatively regulates rRNA expression | 44 | 7.19e-01 | 3.14e-02 | 9.54e-01 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | 28 | 7.19e-01 | 3.94e-02 | 9.54e-01 |
| B-WICH complex positively regulates rRNA expression | 29 | 7.19e-01 | 3.86e-02 | 9.54e-01 |
| Rev-mediated nuclear export of HIV RNA | 34 | 7.20e-01 | 3.55e-02 | 9.54e-01 |
| Negative regulators of DDX58/IFIH1 signaling | 35 | 7.20e-01 | 3.50e-02 | 9.54e-01 |
| Late Phase of HIV Life Cycle | 132 | 7.21e-01 | -1.81e-02 | 9.54e-01 |
| Sensory processing of sound | 43 | 7.22e-01 | 3.14e-02 | 9.55e-01 |
| Condensation of Prophase Chromosomes | 14 | 7.24e-01 | 5.46e-02 | 9.56e-01 |
| p75NTR recruits signalling complexes | 12 | 7.26e-01 | -5.85e-02 | 9.57e-01 |
| IRS-related events triggered by IGF1R | 34 | 7.27e-01 | -3.47e-02 | 9.57e-01 |
| RNA Polymerase III Transcription Termination | 23 | 7.27e-01 | 4.21e-02 | 9.57e-01 |
| Regulation of APC/C activators between G1/S and early anaphase | 77 | 7.29e-01 | 2.28e-02 | 9.60e-01 |
| Interferon gamma signaling | 57 | 7.30e-01 | 2.65e-02 | 9.60e-01 |
| Degradation of cysteine and homocysteine | 12 | 7.30e-01 | -5.75e-02 | 9.60e-01 |
| IRAK2 mediated activation of TAK1 complex | 10 | 7.32e-01 | 6.25e-02 | 9.61e-01 |
| Signaling by CSF3 (G-CSF) | 27 | 7.33e-01 | 3.80e-02 | 9.61e-01 |
| Generation of second messenger molecules | 14 | 7.34e-01 | 5.25e-02 | 9.61e-01 |
| PI3K Cascade | 28 | 7.38e-01 | -3.66e-02 | 9.64e-01 |
| RNA Polymerase I Transcription Termination | 27 | 7.40e-01 | 3.69e-02 | 9.64e-01 |
| CTLA4 inhibitory signaling | 17 | 7.40e-01 | -4.64e-02 | 9.64e-01 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | 14 | 7.42e-01 | 5.09e-02 | 9.64e-01 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | 71 | 7.42e-01 | 2.26e-02 | 9.64e-01 |
| Axon guidance | 424 | 7.42e-01 | 9.35e-03 | 9.64e-01 |
| Signaling by the B Cell Receptor (BCR) | 96 | 7.43e-01 | 1.94e-02 | 9.64e-01 |
| FOXO-mediated transcription of cell cycle genes | 14 | 7.44e-01 | 5.04e-02 | 9.64e-01 |
| Transcription of the HIV genome | 67 | 7.45e-01 | -2.30e-02 | 9.64e-01 |
| Lysine catabolism | 12 | 7.47e-01 | 5.38e-02 | 9.64e-01 |
| Metabolism of non-coding RNA | 52 | 7.47e-01 | 2.59e-02 | 9.64e-01 |
| snRNP Assembly | 52 | 7.47e-01 | 2.59e-02 | 9.64e-01 |
| Insulin processing | 22 | 7.47e-01 | -3.97e-02 | 9.64e-01 |
| APC/C-mediated degradation of cell cycle proteins | 84 | 7.48e-01 | 2.03e-02 | 9.64e-01 |
| Regulation of mitotic cell cycle | 84 | 7.48e-01 | 2.03e-02 | 9.64e-01 |
| Sphingolipid de novo biosynthesis | 38 | 7.50e-01 | -2.98e-02 | 9.64e-01 |
| Defective EXT1 causes exostoses 1, TRPS2 and CHDS | 13 | 7.51e-01 | -5.09e-02 | 9.64e-01 |
| Defective EXT2 causes exostoses 2 | 13 | 7.51e-01 | -5.09e-02 | 9.64e-01 |
| SUMOylation | 162 | 7.52e-01 | 1.44e-02 | 9.64e-01 |
| Processing of Capped Intronless Pre-mRNA | 28 | 7.52e-01 | -3.45e-02 | 9.64e-01 |
| SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | 11 | 7.52e-01 | -5.49e-02 | 9.64e-01 |
| Anti-inflammatory response favouring Leishmania parasite infection | 63 | 7.54e-01 | -2.29e-02 | 9.64e-01 |
| Leishmania parasite growth and survival | 63 | 7.54e-01 | -2.29e-02 | 9.64e-01 |
| Organic cation/anion/zwitterion transport | 11 | 7.54e-01 | -5.45e-02 | 9.64e-01 |
| SUMOylation of intracellular receptors | 25 | 7.55e-01 | -3.60e-02 | 9.64e-01 |
| RNA Polymerase III Chain Elongation | 18 | 7.58e-01 | 4.19e-02 | 9.64e-01 |
| SUMOylation of DNA damage response and repair proteins | 76 | 7.60e-01 | -2.03e-02 | 9.64e-01 |
| HIV Transcription Initiation | 45 | 7.61e-01 | -2.62e-02 | 9.64e-01 |
| RNA Polymerase II HIV Promoter Escape | 45 | 7.61e-01 | -2.62e-02 | 9.64e-01 |
| RNA Polymerase II Promoter Escape | 45 | 7.61e-01 | -2.62e-02 | 9.64e-01 |
| RNA Polymerase II Transcription Initiation | 45 | 7.61e-01 | -2.62e-02 | 9.64e-01 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | 45 | 7.61e-01 | -2.62e-02 | 9.64e-01 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | 45 | 7.61e-01 | -2.62e-02 | 9.64e-01 |
| Regulation of FZD by ubiquitination | 15 | 7.62e-01 | -4.52e-02 | 9.64e-01 |
| Degradation of GLI1 by the proteasome | 55 | 7.63e-01 | 2.35e-02 | 9.64e-01 |
| Defects in cobalamin (B12) metabolism | 12 | 7.64e-01 | 5.00e-02 | 9.64e-01 |
| Adherens junctions interactions | 20 | 7.65e-01 | -3.87e-02 | 9.64e-01 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | 14 | 7.65e-01 | 4.62e-02 | 9.64e-01 |
| TCF dependent signaling in response to WNT | 145 | 7.65e-01 | 1.44e-02 | 9.64e-01 |
| Cyclin A:Cdk2-associated events at S phase entry | 82 | 7.66e-01 | -1.90e-02 | 9.64e-01 |
| Downstream signal transduction | 28 | 7.66e-01 | 3.25e-02 | 9.64e-01 |
| HDR through MMEJ (alt-NHEJ) | 10 | 7.66e-01 | 5.43e-02 | 9.64e-01 |
| Autodegradation of the E3 ubiquitin ligase COP1 | 49 | 7.67e-01 | 2.45e-02 | 9.64e-01 |
| DCC mediated attractive signaling | 12 | 7.68e-01 | 4.92e-02 | 9.64e-01 |
| Generic Transcription Pathway | 1024 | 7.68e-01 | 5.51e-03 | 9.64e-01 |
| SUMO E3 ligases SUMOylate target proteins | 156 | 7.69e-01 | 1.37e-02 | 9.64e-01 |
| Costimulation by the CD28 family | 41 | 7.69e-01 | -2.65e-02 | 9.64e-01 |
| Activation of the AP-1 family of transcription factors | 10 | 7.70e-01 | -5.35e-02 | 9.64e-01 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | 26 | 7.70e-01 | 3.31e-02 | 9.64e-01 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | 10 | 7.71e-01 | -5.32e-02 | 9.64e-01 |
| Signaling by KIT in disease | 19 | 7.73e-01 | -3.82e-02 | 9.64e-01 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | 19 | 7.73e-01 | -3.82e-02 | 9.64e-01 |
| EGFR downregulation | 26 | 7.73e-01 | 3.26e-02 | 9.64e-01 |
| Signaling by FLT3 ITD and TKD mutants | 14 | 7.74e-01 | 4.44e-02 | 9.64e-01 |
| Formation of the cornified envelope | 21 | 7.76e-01 | 3.59e-02 | 9.65e-01 |
| Activation of SMO | 14 | 7.77e-01 | 4.38e-02 | 9.65e-01 |
| Activation of HOX genes during differentiation | 52 | 7.79e-01 | 2.25e-02 | 9.65e-01 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | 52 | 7.79e-01 | 2.25e-02 | 9.65e-01 |
| Cardiac conduction | 66 | 7.79e-01 | 2.00e-02 | 9.65e-01 |
| CDK-mediated phosphorylation and removal of Cdc6 | 69 | 7.80e-01 | 1.95e-02 | 9.65e-01 |
| Selective autophagy | 56 | 7.80e-01 | 2.16e-02 | 9.65e-01 |
| Regulation of KIT signaling | 15 | 7.82e-01 | -4.13e-02 | 9.65e-01 |
| Signaling by NOTCH1 | 62 | 7.82e-01 | 2.04e-02 | 9.65e-01 |
| Assembly of collagen fibrils and other multimeric structures | 34 | 7.82e-01 | 2.74e-02 | 9.65e-01 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | 25 | 7.82e-01 | 3.19e-02 | 9.65e-01 |
| SHC-mediated cascade:FGFR1 | 10 | 7.84e-01 | -5.01e-02 | 9.65e-01 |
| Signaling by PDGFR in disease | 17 | 7.84e-01 | -3.84e-02 | 9.65e-01 |
| RMTs methylate histone arginines | 30 | 7.85e-01 | -2.88e-02 | 9.65e-01 |
| SUMOylation of transcription cofactors | 43 | 7.85e-01 | 2.40e-02 | 9.65e-01 |
| NF-kB is activated and signals survival | 12 | 7.86e-01 | -4.52e-02 | 9.65e-01 |
| RIPK1-mediated regulated necrosis | 27 | 7.87e-01 | -3.00e-02 | 9.65e-01 |
| Regulation of necroptotic cell death | 27 | 7.87e-01 | -3.00e-02 | 9.65e-01 |
| SHC-mediated cascade:FGFR2 | 10 | 7.89e-01 | -4.89e-02 | 9.66e-01 |
| Signaling by EGFR in Cancer | 22 | 7.90e-01 | 3.29e-02 | 9.66e-01 |
| Activated NOTCH1 Transmits Signal to the Nucleus | 25 | 7.90e-01 | 3.07e-02 | 9.66e-01 |
| ADP signalling through P2Y purinoceptor 1 | 13 | 7.91e-01 | -4.25e-02 | 9.66e-01 |
| CDC6 association with the ORC:origin complex | 11 | 7.92e-01 | 4.60e-02 | 9.66e-01 |
| Signaling by VEGF | 89 | 7.92e-01 | 1.62e-02 | 9.66e-01 |
| Protein folding | 78 | 7.97e-01 | -1.69e-02 | 9.68e-01 |
| Signaling by ERBB2 | 42 | 7.97e-01 | 2.29e-02 | 9.68e-01 |
| SHC-mediated cascade:FGFR4 | 10 | 7.98e-01 | -4.68e-02 | 9.68e-01 |
| Dual incision in TC-NER | 65 | 7.98e-01 | 1.84e-02 | 9.68e-01 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | 14 | 7.99e-01 | 3.94e-02 | 9.68e-01 |
| Regulation of PLK1 Activity at G2/M Transition | 84 | 7.99e-01 | -1.61e-02 | 9.68e-01 |
| G2/M Transition | 175 | 8.00e-01 | 1.11e-02 | 9.68e-01 |
| SUMOylation of SUMOylation proteins | 34 | 8.00e-01 | 2.51e-02 | 9.68e-01 |
| Mitotic G2-G2/M phases | 177 | 8.00e-01 | 1.10e-02 | 9.68e-01 |
| HuR (ELAVL1) binds and stabilizes mRNA | 10 | 8.03e-01 | 4.56e-02 | 9.69e-01 |
| HCMV Infection | 82 | 8.03e-01 | -1.59e-02 | 9.69e-01 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | 22 | 8.04e-01 | -3.05e-02 | 9.69e-01 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | 28 | 8.05e-01 | -2.69e-02 | 9.69e-01 |
| MET activates RAS signaling | 10 | 8.06e-01 | 4.48e-02 | 9.69e-01 |
| Degradation of GLI2 by the proteasome | 55 | 8.07e-01 | 1.91e-02 | 9.69e-01 |
| GLI3 is processed to GLI3R by the proteasome | 55 | 8.07e-01 | 1.91e-02 | 9.69e-01 |
| Chemokine receptors bind chemokines | 13 | 8.07e-01 | 3.92e-02 | 9.69e-01 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | 13 | 8.07e-01 | 3.91e-02 | 9.69e-01 |
| Cyclin E associated events during G1/S transition | 80 | 8.08e-01 | -1.57e-02 | 9.69e-01 |
| C-type lectin receptors (CLRs) | 113 | 8.12e-01 | 1.30e-02 | 9.71e-01 |
| Translation initiation complex formation | 58 | 8.13e-01 | -1.80e-02 | 9.71e-01 |
| Regulation of TP53 Activity through Acetylation | 29 | 8.13e-01 | -2.54e-02 | 9.71e-01 |
| Synthesis of glycosylphosphatidylinositol (GPI) | 18 | 8.13e-01 | -3.21e-02 | 9.71e-01 |
| Ovarian tumor domain proteases | 36 | 8.14e-01 | 2.27e-02 | 9.71e-01 |
| Glycogen storage diseases | 13 | 8.14e-01 | -3.76e-02 | 9.71e-01 |
| RHOBTB1 GTPase cycle | 21 | 8.16e-01 | 2.94e-02 | 9.71e-01 |
| Diseases associated with glycosaminoglycan metabolism | 29 | 8.16e-01 | 2.50e-02 | 9.71e-01 |
| GRB2 events in EGFR signaling | 10 | 8.16e-01 | 4.25e-02 | 9.71e-01 |
| Sensory processing of sound by outer hair cells of the cochlea | 31 | 8.17e-01 | -2.41e-02 | 9.71e-01 |
| Synaptic adhesion-like molecules | 14 | 8.17e-01 | -3.57e-02 | 9.71e-01 |
| Formation of Incision Complex in GG-NER | 43 | 8.18e-01 | -2.03e-02 | 9.71e-01 |
| Epigenetic regulation of gene expression | 85 | 8.19e-01 | 1.43e-02 | 9.72e-01 |
| Purine catabolism | 14 | 8.21e-01 | -3.50e-02 | 9.72e-01 |
| EPH-ephrin mediated repulsion of cells | 38 | 8.25e-01 | 2.08e-02 | 9.73e-01 |
| RHO GTPases Activate NADPH Oxidases | 16 | 8.25e-01 | -3.20e-02 | 9.73e-01 |
| Metabolism of cofactors | 18 | 8.25e-01 | 3.01e-02 | 9.73e-01 |
| Thromboxane signalling through TP receptor | 14 | 8.25e-01 | 3.41e-02 | 9.73e-01 |
| Signaling by FLT3 fusion proteins | 18 | 8.27e-01 | -2.97e-02 | 9.73e-01 |
| Regulation of TP53 Activity through Association with Co-factors | 11 | 8.28e-01 | -3.79e-02 | 9.73e-01 |
| HIV elongation arrest and recovery | 32 | 8.30e-01 | -2.20e-02 | 9.73e-01 |
| Pausing and recovery of HIV elongation | 32 | 8.30e-01 | -2.20e-02 | 9.73e-01 |
| ADORA2B mediated anti-inflammatory cytokines production | 42 | 8.31e-01 | -1.90e-02 | 9.73e-01 |
| Formation of the Early Elongation Complex | 33 | 8.32e-01 | 2.14e-02 | 9.73e-01 |
| Formation of the HIV-1 Early Elongation Complex | 33 | 8.32e-01 | 2.14e-02 | 9.73e-01 |
| Rab regulation of trafficking | 114 | 8.32e-01 | 1.15e-02 | 9.73e-01 |
| Antigen processing: Ubiquitination & Proteasome degradation | 279 | 8.32e-01 | -7.39e-03 | 9.73e-01 |
| tRNA processing in the nucleus | 54 | 8.32e-01 | -1.67e-02 | 9.73e-01 |
| Factors involved in megakaryocyte development and platelet production | 103 | 8.33e-01 | 1.21e-02 | 9.73e-01 |
| Defects in vitamin and cofactor metabolism | 20 | 8.33e-01 | 2.73e-02 | 9.73e-01 |
| FGFR2 mutant receptor activation | 20 | 8.33e-01 | 2.72e-02 | 9.73e-01 |
| Signaling by ERBB2 ECD mutants | 15 | 8.35e-01 | -3.11e-02 | 9.74e-01 |
| Transport of Mature Transcript to Cytoplasm | 80 | 8.37e-01 | 1.33e-02 | 9.75e-01 |
| Sensory processing of sound by inner hair cells of the cochlea | 39 | 8.38e-01 | 1.89e-02 | 9.75e-01 |
| SCF-beta-TrCP mediated degradation of Emi1 | 52 | 8.39e-01 | 1.63e-02 | 9.75e-01 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | 51 | 8.39e-01 | 1.65e-02 | 9.75e-01 |
| ECM proteoglycans | 32 | 8.41e-01 | -2.06e-02 | 9.75e-01 |
| RHO GTPases activate KTN1 | 11 | 8.42e-01 | 3.47e-02 | 9.75e-01 |
| Regulation of actin dynamics for phagocytic cup formation | 49 | 8.42e-01 | 1.64e-02 | 9.75e-01 |
| Phospholipid metabolism | 160 | 8.42e-01 | 9.12e-03 | 9.75e-01 |
| Regulation of TP53 Activity through Phosphorylation | 88 | 8.43e-01 | -1.23e-02 | 9.75e-01 |
| Surfactant metabolism | 14 | 8.43e-01 | -3.06e-02 | 9.75e-01 |
| Regulation of MECP2 expression and activity | 29 | 8.43e-01 | 2.12e-02 | 9.75e-01 |
| Carnitine metabolism | 11 | 8.44e-01 | 3.42e-02 | 9.75e-01 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | 17 | 8.46e-01 | 2.72e-02 | 9.77e-01 |
| Sulfur amino acid metabolism | 26 | 8.48e-01 | -2.17e-02 | 9.77e-01 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | 13 | 8.48e-01 | 3.07e-02 | 9.77e-01 |
| Stabilization of p53 | 54 | 8.51e-01 | 1.48e-02 | 9.78e-01 |
| RAB GEFs exchange GTP for GDP on RABs | 82 | 8.53e-01 | -1.19e-02 | 9.78e-01 |
| InlB-mediated entry of Listeria monocytogenes into host cell | 13 | 8.53e-01 | 2.97e-02 | 9.78e-01 |
| G beta:gamma signalling through PLC beta | 11 | 8.53e-01 | 3.23e-02 | 9.78e-01 |
| Presynaptic function of Kainate receptors | 11 | 8.53e-01 | 3.23e-02 | 9.78e-01 |
| Striated Muscle Contraction | 18 | 8.54e-01 | -2.50e-02 | 9.78e-01 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | 12 | 8.54e-01 | 3.06e-02 | 9.78e-01 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | 20 | 8.55e-01 | -2.37e-02 | 9.78e-01 |
| Notch-HLH transcription pathway | 24 | 8.55e-01 | -2.15e-02 | 9.78e-01 |
| ZBP1(DAI) mediated induction of type I IFNs | 17 | 8.56e-01 | 2.55e-02 | 9.78e-01 |
| Constitutive Signaling by Overexpressed ERBB2 | 11 | 8.57e-01 | 3.14e-02 | 9.78e-01 |
| Hyaluronan uptake and degradation | 10 | 8.57e-01 | 3.29e-02 | 9.78e-01 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | 13 | 8.61e-01 | -2.80e-02 | 9.81e-01 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | 59 | 8.61e-01 | -1.32e-02 | 9.81e-01 |
| Signaling by EGFR | 44 | 8.62e-01 | 1.52e-02 | 9.81e-01 |
| Heme biosynthesis | 13 | 8.63e-01 | -2.77e-02 | 9.81e-01 |
| MTOR signalling | 40 | 8.64e-01 | 1.56e-02 | 9.82e-01 |
| PKMTs methylate histone lysines | 41 | 8.68e-01 | 1.50e-02 | 9.86e-01 |
| FLT3 signaling in disease | 26 | 8.69e-01 | 1.86e-02 | 9.86e-01 |
| Positive epigenetic regulation of rRNA expression | 44 | 8.70e-01 | -1.43e-02 | 9.86e-01 |
| NIK–>noncanonical NF-kB signaling | 56 | 8.71e-01 | -1.26e-02 | 9.86e-01 |
| eNOS activation | 10 | 8.72e-01 | -2.95e-02 | 9.86e-01 |
| Toll Like Receptor 3 (TLR3) Cascade | 85 | 8.77e-01 | 9.69e-03 | 9.90e-01 |
| Signaling by ERBB2 in Cancer | 19 | 8.78e-01 | 2.04e-02 | 9.90e-01 |
| HSF1-dependent transactivation | 30 | 8.78e-01 | 1.62e-02 | 9.90e-01 |
| p38MAPK events | 13 | 8.78e-01 | 2.45e-02 | 9.90e-01 |
| Formation of HIV elongation complex in the absence of HIV Tat | 44 | 8.79e-01 | -1.33e-02 | 9.90e-01 |
| rRNA modification in the nucleus and cytosol | 58 | 8.80e-01 | 1.14e-02 | 9.90e-01 |
| Signaling by ERBB2 TMD/JMD mutants | 15 | 8.81e-01 | 2.23e-02 | 9.90e-01 |
| Interleukin receptor SHC signaling | 17 | 8.81e-01 | -2.10e-02 | 9.90e-01 |
| Association of TriC/CCT with target proteins during biosynthesis | 38 | 8.82e-01 | 1.39e-02 | 9.91e-01 |
| The canonical retinoid cycle in rods (twilight vision) | 16 | 8.84e-01 | 2.11e-02 | 9.91e-01 |
| Assembly Of The HIV Virion | 16 | 8.84e-01 | 2.11e-02 | 9.91e-01 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | 45 | 8.85e-01 | 1.25e-02 | 9.91e-01 |
| CD28 dependent PI3K/Akt signaling | 18 | 8.86e-01 | -1.96e-02 | 9.91e-01 |
| Purine salvage | 11 | 8.86e-01 | 2.49e-02 | 9.91e-01 |
| Pyruvate metabolism | 24 | 8.88e-01 | -1.67e-02 | 9.91e-01 |
| Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane | 11 | 8.88e-01 | -2.46e-02 | 9.91e-01 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | 13 | 8.89e-01 | -2.23e-02 | 9.92e-01 |
| Defective B4GALT7 causes EDS, progeroid type | 14 | 8.90e-01 | 2.13e-02 | 9.93e-01 |
| ABC transporters in lipid homeostasis | 14 | 8.92e-01 | -2.10e-02 | 9.93e-01 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | 27 | 8.93e-01 | 1.50e-02 | 9.93e-01 |
| TRAF6 mediated NF-kB activation | 22 | 8.93e-01 | 1.66e-02 | 9.93e-01 |
| Gene expression (Transcription) | 1265 | 8.96e-01 | -2.23e-03 | 9.95e-01 |
| mRNA Splicing - Major Pathway | 178 | 9.00e-01 | -5.48e-03 | 9.95e-01 |
| Signaling by FGFR1 | 38 | 9.01e-01 | 1.17e-02 | 9.95e-01 |
| CLEC7A (Dectin-1) signaling | 92 | 9.01e-01 | 7.49e-03 | 9.95e-01 |
| Potential therapeutics for SARS | 77 | 9.01e-01 | 8.18e-03 | 9.95e-01 |
| Protein methylation | 15 | 9.01e-01 | -1.85e-02 | 9.95e-01 |
| Regulation of TP53 Activity | 152 | 9.02e-01 | -5.82e-03 | 9.95e-01 |
| Signal amplification | 19 | 9.02e-01 | 1.63e-02 | 9.95e-01 |
| Autodegradation of Cdh1 by Cdh1:APC/C | 63 | 9.03e-01 | -8.91e-03 | 9.95e-01 |
| Late endosomal microautophagy | 29 | 9.05e-01 | 1.29e-02 | 9.95e-01 |
| Erythropoietin activates RAS | 13 | 9.05e-01 | -1.91e-02 | 9.95e-01 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | 78 | 9.07e-01 | 7.68e-03 | 9.95e-01 |
| Processing of Capped Intron-Containing Pre-mRNA | 236 | 9.07e-01 | -4.41e-03 | 9.95e-01 |
| GAB1 signalosome | 14 | 9.09e-01 | -1.77e-02 | 9.95e-01 |
| VEGFR2 mediated cell proliferation | 17 | 9.10e-01 | -1.58e-02 | 9.95e-01 |
| Smooth Muscle Contraction | 28 | 9.11e-01 | 1.22e-02 | 9.95e-01 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | 21 | 9.12e-01 | -1.39e-02 | 9.95e-01 |
| Cargo recognition for clathrin-mediated endocytosis | 81 | 9.15e-01 | 6.86e-03 | 9.95e-01 |
| IRAK1 recruits IKK complex | 10 | 9.17e-01 | -1.90e-02 | 9.95e-01 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | 10 | 9.17e-01 | -1.90e-02 | 9.95e-01 |
| SUMOylation of ubiquitinylation proteins | 38 | 9.19e-01 | -9.50e-03 | 9.95e-01 |
| Norepinephrine Neurotransmitter Release Cycle | 11 | 9.20e-01 | 1.76e-02 | 9.95e-01 |
| CD209 (DC-SIGN) signaling | 18 | 9.20e-01 | -1.37e-02 | 9.95e-01 |
| RNA Polymerase I Promoter Escape | 29 | 9.21e-01 | 1.07e-02 | 9.95e-01 |
| G-protein activation | 11 | 9.21e-01 | -1.73e-02 | 9.95e-01 |
| Signaling by WNT in cancer | 32 | 9.22e-01 | -1.01e-02 | 9.95e-01 |
| DNA Double Strand Break Response | 40 | 9.22e-01 | 8.91e-03 | 9.95e-01 |
| Anchoring of the basal body to the plasma membrane | 93 | 9.24e-01 | 5.76e-03 | 9.95e-01 |
| Cellular response to starvation | 149 | 9.24e-01 | 4.55e-03 | 9.95e-01 |
| HCMV Early Events | 58 | 9.24e-01 | 7.21e-03 | 9.95e-01 |
| Cellular hexose transport | 16 | 9.25e-01 | -1.36e-02 | 9.95e-01 |
| NOTCH1 Intracellular Domain Regulates Transcription | 42 | 9.25e-01 | 8.40e-03 | 9.95e-01 |
| Keratan sulfate biosynthesis | 20 | 9.25e-01 | -1.21e-02 | 9.95e-01 |
| Signaling by Erythropoietin | 22 | 9.26e-01 | 1.14e-02 | 9.95e-01 |
| Synthesis of bile acids and bile salts | 31 | 9.26e-01 | -9.60e-03 | 9.95e-01 |
| p75 NTR receptor-mediated signalling | 82 | 9.27e-01 | 5.84e-03 | 9.95e-01 |
| Signaling by Activin | 12 | 9.30e-01 | 1.47e-02 | 9.95e-01 |
| RHO GTPases Activate WASPs and WAVEs | 32 | 9.32e-01 | 8.71e-03 | 9.95e-01 |
| Fc epsilon receptor (FCERI) signaling | 113 | 9.33e-01 | -4.55e-03 | 9.95e-01 |
| Leishmania infection | 133 | 9.34e-01 | 4.16e-03 | 9.95e-01 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | 18 | 9.34e-01 | -1.13e-02 | 9.95e-01 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | 18 | 9.34e-01 | -1.13e-02 | 9.95e-01 |
| G1/S DNA Damage Checkpoints | 64 | 9.35e-01 | 5.89e-03 | 9.95e-01 |
| Signaling by Retinoic Acid | 33 | 9.35e-01 | 8.17e-03 | 9.95e-01 |
| mRNA Splicing - Minor Pathway | 52 | 9.36e-01 | -6.48e-03 | 9.95e-01 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | 13 | 9.36e-01 | 1.29e-02 | 9.95e-01 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | 11 | 9.37e-01 | 1.39e-02 | 9.95e-01 |
| mRNA Splicing | 186 | 9.37e-01 | -3.36e-03 | 9.95e-01 |
| Synthesis of bile acids and bile salts via 27-hydroxycholesterol | 14 | 9.38e-01 | -1.21e-02 | 9.95e-01 |
| VEGFA-VEGFR2 Pathway | 83 | 9.40e-01 | -4.80e-03 | 9.95e-01 |
| APC-Cdc20 mediated degradation of Nek2A | 26 | 9.40e-01 | 8.49e-03 | 9.95e-01 |
| G alpha (z) signalling events | 25 | 9.41e-01 | -8.58e-03 | 9.95e-01 |
| Transcriptional Regulation by MECP2 | 45 | 9.41e-01 | -6.40e-03 | 9.95e-01 |
| Formation of tubulin folding intermediates by CCT/TriC | 20 | 9.42e-01 | -9.44e-03 | 9.95e-01 |
| Ribosomal scanning and start codon recognition | 58 | 9.42e-01 | -5.55e-03 | 9.95e-01 |
| p53-Dependent G1 DNA Damage Response | 62 | 9.43e-01 | -5.27e-03 | 9.95e-01 |
| p53-Dependent G1/S DNA damage checkpoint | 62 | 9.43e-01 | -5.27e-03 | 9.95e-01 |
| Defective B3GAT3 causes JDSSDHD | 14 | 9.43e-01 | 1.11e-02 | 9.95e-01 |
| Ca2+ pathway | 44 | 9.44e-01 | 6.17e-03 | 9.95e-01 |
| HIV Infection | 217 | 9.45e-01 | -2.74e-03 | 9.95e-01 |
| Processing of SMDT1 | 15 | 9.45e-01 | 1.03e-02 | 9.95e-01 |
| Regulation of IFNG signaling | 13 | 9.46e-01 | -1.09e-02 | 9.95e-01 |
| HCMV Late Events | 55 | 9.46e-01 | -5.31e-03 | 9.95e-01 |
| RNA Polymerase I Promoter Clearance | 48 | 9.47e-01 | 5.55e-03 | 9.95e-01 |
| RNA Polymerase I Transcription | 48 | 9.47e-01 | 5.55e-03 | 9.95e-01 |
| Negative regulation of FGFR3 signaling | 21 | 9.48e-01 | -8.28e-03 | 9.95e-01 |
| Endogenous sterols | 22 | 9.48e-01 | -8.06e-03 | 9.95e-01 |
| RAF activation | 33 | 9.48e-01 | -6.55e-03 | 9.95e-01 |
| Signaling by ERBB2 KD Mutants | 18 | 9.48e-01 | -8.86e-03 | 9.95e-01 |
| IGF1R signaling cascade | 35 | 9.48e-01 | -6.32e-03 | 9.95e-01 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | 35 | 9.48e-01 | -6.32e-03 | 9.95e-01 |
| Protein ubiquitination | 64 | 9.49e-01 | 4.60e-03 | 9.95e-01 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | 12 | 9.50e-01 | 1.05e-02 | 9.95e-01 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | 12 | 9.50e-01 | 1.05e-02 | 9.95e-01 |
| Trafficking and processing of endosomal TLR | 10 | 9.51e-01 | 1.13e-02 | 9.95e-01 |
| Maturation of nucleoprotein | 11 | 9.51e-01 | 1.08e-02 | 9.95e-01 |
| Regulation of RAS by GAPs | 62 | 9.52e-01 | 4.41e-03 | 9.95e-01 |
| Downregulation of ERBB2:ERBB3 signaling | 10 | 9.53e-01 | 1.07e-02 | 9.95e-01 |
| Prefoldin mediated transfer of substrate to CCT/TriC | 25 | 9.54e-01 | 6.73e-03 | 9.95e-01 |
| AURKA Activation by TPX2 | 69 | 9.54e-01 | 4.04e-03 | 9.95e-01 |
| Chaperonin-mediated protein folding | 72 | 9.55e-01 | -3.86e-03 | 9.95e-01 |
| FCERI mediated MAPK activation | 25 | 9.55e-01 | -6.46e-03 | 9.95e-01 |
| FCGR3A-mediated phagocytosis | 47 | 9.56e-01 | -4.69e-03 | 9.95e-01 |
| Leishmania phagocytosis | 47 | 9.56e-01 | -4.69e-03 | 9.95e-01 |
| Parasite infection | 47 | 9.56e-01 | -4.69e-03 | 9.95e-01 |
| MyD88-independent TLR4 cascade | 88 | 9.58e-01 | 3.22e-03 | 9.95e-01 |
| TRIF(TICAM1)-mediated TLR4 signaling | 88 | 9.58e-01 | 3.22e-03 | 9.95e-01 |
| Downregulation of ERBB2 signaling | 21 | 9.59e-01 | 6.46e-03 | 9.95e-01 |
| Regulation of TP53 Activity through Methylation | 19 | 9.59e-01 | 6.77e-03 | 9.95e-01 |
| Regulation of PTEN gene transcription | 58 | 9.61e-01 | 3.69e-03 | 9.95e-01 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | 71 | 9.61e-01 | -3.32e-03 | 9.95e-01 |
| RNA Polymerase III Abortive And Retractive Initiation | 41 | 9.64e-01 | 4.04e-03 | 9.95e-01 |
| RNA Polymerase III Transcription | 41 | 9.64e-01 | 4.04e-03 | 9.95e-01 |
| SCF(Skp2)-mediated degradation of p27/p21 | 58 | 9.66e-01 | 3.29e-03 | 9.95e-01 |
| Transcriptional Regulation by E2F6 | 34 | 9.67e-01 | 4.14e-03 | 9.95e-01 |
| Peptide hormone metabolism | 50 | 9.67e-01 | 3.35e-03 | 9.95e-01 |
| Triglyceride catabolism | 12 | 9.68e-01 | 6.77e-03 | 9.95e-01 |
| NRAGE signals death through JNK | 48 | 9.69e-01 | -3.27e-03 | 9.95e-01 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | 21 | 9.69e-01 | 4.94e-03 | 9.95e-01 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | 21 | 9.69e-01 | 4.94e-03 | 9.95e-01 |
| TP53 Regulates Metabolic Genes | 84 | 9.70e-01 | 2.39e-03 | 9.95e-01 |
| ADP signalling through P2Y purinoceptor 12 | 12 | 9.70e-01 | 6.27e-03 | 9.95e-01 |
| Glycogen synthesis | 14 | 9.70e-01 | -5.78e-03 | 9.95e-01 |
| p75NTR signals via NF-kB | 15 | 9.71e-01 | -5.46e-03 | 9.95e-01 |
| Constitutive Signaling by EGFRvIII | 14 | 9.72e-01 | 5.41e-03 | 9.95e-01 |
| Signaling by EGFRvIII in Cancer | 14 | 9.72e-01 | 5.41e-03 | 9.95e-01 |
| Intrinsic Pathway for Apoptosis | 50 | 9.72e-01 | -2.86e-03 | 9.95e-01 |
| Signal transduction by L1 | 18 | 9.78e-01 | -3.83e-03 | 9.98e-01 |
| Global Genome Nucleotide Excision Repair (GG-NER) | 84 | 9.78e-01 | 1.76e-03 | 9.98e-01 |
| Intra-Golgi traffic | 40 | 9.79e-01 | -2.44e-03 | 9.98e-01 |
| Pausing and recovery of Tat-mediated HIV elongation | 30 | 9.79e-01 | -2.81e-03 | 9.98e-01 |
| Tat-mediated HIV elongation arrest and recovery | 30 | 9.79e-01 | -2.81e-03 | 9.98e-01 |
| RNA Polymerase II Transcription | 1142 | 9.80e-01 | -4.55e-04 | 9.98e-01 |
| Negative regulation of NOTCH4 signaling | 52 | 9.80e-01 | -1.98e-03 | 9.98e-01 |
| FCERI mediated Ca+2 mobilization | 20 | 9.81e-01 | -3.06e-03 | 9.98e-01 |
| Signaling by FGFR4 | 31 | 9.82e-01 | 2.30e-03 | 9.98e-01 |
| Processing of Intronless Pre-mRNAs | 19 | 9.83e-01 | 2.81e-03 | 9.98e-01 |
| Platelet sensitization by LDL | 15 | 9.85e-01 | -2.87e-03 | 9.98e-01 |
| Loss of Nlp from mitotic centrosomes | 66 | 9.85e-01 | -1.31e-03 | 9.98e-01 |
| Loss of proteins required for interphase microtubule organization from the centrosome | 66 | 9.85e-01 | -1.31e-03 | 9.98e-01 |
| Alpha-protein kinase 1 signaling pathway | 11 | 9.87e-01 | -2.90e-03 | 9.98e-01 |
| Signaling by SCF-KIT | 37 | 9.88e-01 | 1.38e-03 | 9.98e-01 |
| HIV Life Cycle | 143 | 9.88e-01 | 7.05e-04 | 9.98e-01 |
| RNA Polymerase III Transcription Initiation | 36 | 9.89e-01 | -1.36e-03 | 9.98e-01 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | 16 | 9.89e-01 | -2.00e-03 | 9.98e-01 |
| Carboxyterminal post-translational modifications of tubulin | 30 | 9.90e-01 | 1.28e-03 | 9.98e-01 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | 42 | 9.92e-01 | 8.41e-04 | 9.98e-01 |
| HIV Transcription Elongation | 42 | 9.92e-01 | 8.41e-04 | 9.98e-01 |
| Tat-mediated elongation of the HIV-1 transcript | 42 | 9.92e-01 | 8.41e-04 | 9.98e-01 |
| PRC2 methylates histones and DNA | 14 | 9.93e-01 | 1.44e-03 | 9.98e-01 |
| Activation of kainate receptors upon glutamate binding | 16 | 9.93e-01 | 1.34e-03 | 9.98e-01 |
| Stimuli-sensing channels | 59 | 9.93e-01 | 6.42e-04 | 9.98e-01 |
| RNA Polymerase I Transcription Initiation | 44 | 9.94e-01 | -6.34e-04 | 9.98e-01 |
| Cytochrome P450 - arranged by substrate type | 44 | 9.94e-01 | 6.18e-04 | 9.98e-01 |
| PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases | 14 | 9.95e-01 | 9.45e-04 | 9.98e-01 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | 39 | 9.96e-01 | 5.06e-04 | 9.98e-01 |
| Cell death signalling via NRAGE, NRIF and NADE | 65 | 9.98e-01 | 1.89e-04 | 9.99e-01 |
| Death Receptor Signalling | 124 | 9.99e-01 | -8.28e-05 | 9.99e-01 |
| PI3K/AKT Signaling in Cancer | 68 | 1.00e+00 | 3.86e-05 | 1.00e+00 |
Detailed Gene set reports
Unfolded Protein Response (UPR)
| 1318 | |
|---|---|
| set | Unfolded Protein Response (UPR) |
| setSize | 89 |
| pANOVA | 9.26e-10 |
| s.dist | 0.376 |
| p.adjustANOVA | 1.27e-06 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| HSPA5 | 14531 |
| CALR | 14529 |
| DNAJB11 | 14528 |
| HYOU1 | 14527 |
| HERPUD1 | 14524 |
| DNAJC3 | 14516 |
| HSP90B1 | 14514 |
| DNAJB9 | 14510 |
| SYVN1 | 14485 |
| PDIA6 | 14482 |
| EDEM1 | 14479 |
| WFS1 | 14466 |
| GFPT1 | 14406 |
| DDIT3 | 14401 |
| EIF2AK3 | 14371 |
| MYDGF | 14306 |
| SERP1 | 14288 |
| ATF6 | 14261 |
| WIPI1 | 14251 |
| SHC1 | 14209 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HSPA5 | 14531 |
| CALR | 14529 |
| DNAJB11 | 14528 |
| HYOU1 | 14527 |
| HERPUD1 | 14524 |
| DNAJC3 | 14516 |
| HSP90B1 | 14514 |
| DNAJB9 | 14510 |
| SYVN1 | 14485 |
| PDIA6 | 14482 |
| EDEM1 | 14479 |
| WFS1 | 14466 |
| GFPT1 | 14406 |
| DDIT3 | 14401 |
| EIF2AK3 | 14371 |
| MYDGF | 14306 |
| SERP1 | 14288 |
| ATF6 | 14261 |
| WIPI1 | 14251 |
| SHC1 | 14209 |
| ATP6V0D1 | 14206 |
| SSR1 | 14205 |
| FKBP14 | 14184 |
| SRPRB | 14181 |
| ERN1 | 14152 |
| CREB3L2 | 14080 |
| TSPYL2 | 14002 |
| HDGF | 13896 |
| EXOSC6 | 13547 |
| TATDN2 | 13480 |
| TPP1 | 13378 |
| EXTL1 | 13312 |
| TLN1 | 12872 |
| CXXC1 | 12670 |
| CEBPG | 12578 |
| ADD1 | 12538 |
| MBTPS1 | 12523 |
| SEC31A | 12138 |
| ATF4 | 11932 |
| DDX11 | 11907 |
| ASNS | 11814 |
| CREB3L3 | 11433 |
| XBP1 | 11302 |
| CREB3L4 | 11259 |
| EIF2S1 | 10961 |
| PPP2R5B | 10834 |
| DCP2 | 10825 |
| SRPRA | 10175 |
| EXOSC5 | 10117 |
| EXOSC7 | 9819 |
| CREBRF | 9731 |
| PARN | 9715 |
| NFYB | 9634 |
| CTDSP2 | 9444 |
| EIF2S2 | 9437 |
| PLA2G4B | 8953 |
| CUL7 | 8310 |
| IGFBP1 | 8301 |
| KLHDC3 | 8036 |
| ACADVL | 7903 |
| LMNA | 7854 |
| GSK3A | 7787 |
| EIF2S3 | 7757 |
| CREB3 | 7725 |
| EXOSC3 | 7270 |
| EXOSC2 | 7192 |
| MBTPS2 | 7019 |
| CXCL8 | 6916 |
| EXTL3 | 6822 |
| ZBTB17 | 6703 |
| EXOSC1 | 6667 |
| EXTL2 | 6440 |
| EXOSC9 | 6333 |
| EXOSC4 | 6193 |
| NFYA | 5142 |
| ATF3 | 4803 |
| DCTN1 | 3338 |
| ARFGAP1 | 3224 |
| DIS3 | 3190 |
| PREB | 2868 |
| GOSR2 | 2441 |
| CEBPB | 2300 |
| SULT1A3 | 2038 |
| KHSRP | 2029 |
| KDELR3 | 1922 |
| NFYC | 1395 |
| PDIA5 | 1130 |
| EXOSC8 | 928 |
| YIF1A | 381 |
Asparagine N-linked glycosylation
| 74 | |
|---|---|
| set | Asparagine N-linked glycosylation |
| setSize | 252 |
| pANOVA | 7.65e-09 |
| s.dist | 0.212 |
| p.adjustANOVA | 5.12e-06 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CALR | 14529 |
| SEC24D | 14520 |
| SEL1L | 14508 |
| SYVN1 | 14485 |
| EDEM1 | 14479 |
| CANX | 14462 |
| PDIA3 | 14454 |
| SLC17A5 | 14434 |
| TMED2 | 14433 |
| MCFD2 | 14425 |
| GFPT1 | 14406 |
| MIA3 | 14404 |
| DERL2 | 14399 |
| MAGT1 | 14398 |
| RPN1 | 14350 |
| FUT3 | 14335 |
| OS9 | 14320 |
| UGGT1 | 14270 |
| TMED7 | 14240 |
| MVD | 14220 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CALR | 14529 |
| SEC24D | 14520 |
| SEL1L | 14508 |
| SYVN1 | 14485 |
| EDEM1 | 14479 |
| CANX | 14462 |
| PDIA3 | 14454 |
| SLC17A5 | 14434 |
| TMED2 | 14433 |
| MCFD2 | 14425 |
| GFPT1 | 14406 |
| MIA3 | 14404 |
| DERL2 | 14399 |
| MAGT1 | 14398 |
| RPN1 | 14350 |
| FUT3 | 14335 |
| OS9 | 14320 |
| UGGT1 | 14270 |
| TMED7 | 14240 |
| MVD | 14220 |
| NANS | 14204 |
| MLEC | 14193 |
| GMPPB | 14096 |
| SEC24A | 14088 |
| TRAPPC6A | 14069 |
| SEC13 | 14049 |
| ST3GAL4 | 14033 |
| STT3A | 14026 |
| ANK2 | 13993 |
| TMEM115 | 13976 |
| NEU1 | 13953 |
| ST6GALNAC4 | 13912 |
| VCP | 13902 |
| SLC35C1 | 13821 |
| RNF5 | 13745 |
| ALG3 | 13700 |
| TRAPPC10 | 13677 |
| NEU3 | 13653 |
| LMAN2 | 13641 |
| ALG2 | 13631 |
| COPB2 | 13594 |
| CD55 | 13575 |
| PPP6R1 | 13558 |
| ARCN1 | 13549 |
| TMED9 | 13545 |
| ALG5 | 13488 |
| MAN1A2 | 13466 |
| DDOST | 13410 |
| DERL1 | 13398 |
| MGAT1 | 13371 |
| NUS1 | 13362 |
| NEU4 | 13335 |
| RNF185 | 13291 |
| GMPPA | 13267 |
| CHST10 | 13262 |
| CTSA | 13149 |
| MGAT4B | 13132 |
| B4GALT5 | 13121 |
| DAD1 | 13053 |
| SEC24C | 13047 |
| TBC1D20 | 12985 |
| RPN2 | 12964 |
| COG8 | 12910 |
| SEC16B | 12908 |
| RNF103 | 12848 |
| TMED10 | 12817 |
| ALG12 | 12752 |
| DPAGT1 | 12688 |
| ARF1 | 12642 |
| SEC16A | 12546 |
| COPE | 12527 |
| ALG11 | 12520 |
| COG3 | 12497 |
| PRKCSH | 12463 |
| NAPA | 12433 |
| ST3GAL1 | 12408 |
| KDELR2 | 12387 |
| MGAT5 | 12324 |
| ENGASE | 12309 |
| ARF4 | 12225 |
| SEC31A | 12138 |
| RENBP | 12130 |
| CSNK1D | 12038 |
| PSMC1 | 11724 |
| COPG2 | 11691 |
| EDEM2 | 11628 |
| SEC24B | 11541 |
| GNE | 11517 |
| DYNLL2 | 11507 |
| UBXN1 | 11466 |
| PGM3 | 11367 |
| ST3GAL3 | 11257 |
| TFG | 11250 |
| ALG10B | 11213 |
| GOLGA2 | 11209 |
| STX5 | 11191 |
| PPP6C | 11074 |
| PMM2 | 10956 |
| ACTR1A | 10903 |
| CMAS | 10871 |
| COPG1 | 10840 |
| FUT8 | 10839 |
| KDELR1 | 10752 |
| UBA52 | 10707 |
| FPGT | 10685 |
| ACTR10 | 10590 |
| MGAT4A | 10584 |
| DOLPP1 | 10517 |
| GBF1 | 10507 |
| SPTBN1 | 10356 |
| YKT6 | 10349 |
| CAPZA1 | 10272 |
| AMDHD2 | 10267 |
| B4GALT3 | 10265 |
| AREG | 10258 |
| NSF | 10249 |
| ST6GALNAC6 | 10212 |
| ARFGAP3 | 10209 |
| COL7A1 | 10152 |
| ANK1 | 9901 |
| TRAPPC2L | 9709 |
| ST3GAL5 | 9630 |
| RFT1 | 9608 |
| MPI | 9596 |
| ST3GAL2 | 9594 |
| TGFA | 9574 |
| TRAPPC9 | 9528 |
| CTSC | 9398 |
| ALG6 | 9374 |
| ALG1 | 9207 |
| COG7 | 9093 |
| SRD5A3 | 9027 |
| UBB | 9013 |
| ARF5 | 8998 |
| COG2 | 8997 |
| NUDT14 | 8814 |
| COG1 | 8708 |
| COPB1 | 8664 |
| TMED3 | 8567 |
| NAGK | 8559 |
| TRAPPC3 | 8524 |
| COG5 | 8389 |
| COPA | 8376 |
| DCTN2 | 8375 |
| DYNC1LI2 | 8235 |
| NAPG | 8187 |
| MANEA | 7987 |
| ANKRD28 | 7882 |
| DCTN5 | 7690 |
| DYNC1H1 | 7639 |
| SERPINA1 | 7622 |
| MAN1B1 | 7534 |
| SLC35A1 | 7418 |
| USO1 | 7413 |
| GOLGB1 | 7386 |
| SPTBN2 | 7379 |
| RAB1B | 7340 |
| LMAN1 | 7220 |
| LMAN2L | 7218 |
| MPDU1 | 7080 |
| GMDS | 7053 |
| MGAT2 | 7002 |
| RAB1A | 6957 |
| ST3GAL6 | 6829 |
| CD59 | 6818 |
| TRAPPC2 | 6775 |
| ALG14 | 6723 |
| BET1L | 6669 |
| RNF139 | 6382 |
| SEC22A | 6374 |
| COG6 | 6266 |
| ASGR2 | 6225 |
| SAR1B | 6198 |
| DPM3 | 6189 |
| RAD23B | 6054 |
| NGLY1 | 6049 |
| TRAPPC1 | 5956 |
| MAN1C1 | 5920 |
| DYNC1I2 | 5783 |
| RPS27A | 5776 |
| SEC23A | 5659 |
| AMFR | 5612 |
| B4GALT6 | 5555 |
| PMM1 | 5521 |
| GANAB | 5417 |
| DYNC1LI1 | 5237 |
| FUCA1 | 5210 |
| B4GALT2 | 5152 |
| ALG10 | 5133 |
| ARF3 | 5040 |
| B4GALT4 | 5027 |
| STX17 | 4997 |
| TRAPPC6B | 4993 |
| FUOM | 4976 |
| DYNLL1 | 4853 |
| MAN2A2 | 4840 |
| MOGS | 4728 |
| DHDDS | 4636 |
| GNPNAT1 | 4628 |
| SPTAN1 | 4610 |
| ST8SIA1 | 4428 |
| DPM2 | 4373 |
| CNIH3 | 4025 |
| DCTN4 | 3979 |
| EDEM3 | 3904 |
| ASGR1 | 3870 |
| COG4 | 3852 |
| ST6GAL1 | 3739 |
| GORASP1 | 3727 |
| TRIM13 | 3695 |
| ST8SIA5 | 3583 |
| TRAPPC4 | 3487 |
| SEC22C | 3433 |
| MGAT4C | 3364 |
| DCTN1 | 3338 |
| ARFGAP1 | 3224 |
| CAPZA2 | 3143 |
| GLB1 | 3064 |
| DCTN3 | 2887 |
| PREB | 2868 |
| UGGT2 | 2839 |
| B4GALNT2 | 2758 |
| ALG13 | 2687 |
| ARFGAP2 | 2547 |
| DPM1 | 2494 |
| TUSC3 | 2465 |
| GOSR2 | 2441 |
| CAPZB | 2376 |
| ALG8 | 2188 |
| MAN2A1 | 2117 |
| MAN1A1 | 2084 |
| KDELR3 | 1922 |
| UAP1 | 1828 |
| SEC22B | 1690 |
| F5 | 1638 |
| COPZ1 | 1554 |
| UBC | 1551 |
| F8 | 1460 |
| PPP6R3 | 1271 |
| GOSR1 | 1215 |
| SCFD1 | 960 |
| NANP | 957 |
| BET1 | 896 |
| ALG9 | 865 |
| NAPB | 853 |
| SEC23IP | 767 |
| DCTN6 | 666 |
| ANK3 | 591 |
| B4GALT1 | 540 |
| TRAPPC5 | 470 |
| CNIH1 | 416 |
| DOLK | 213 |
IRE1alpha activates chaperones
| 498 | |
|---|---|
| set | IRE1alpha activates chaperones |
| setSize | 50 |
| pANOVA | 1.48e-08 |
| s.dist | 0.463 |
| p.adjustANOVA | 5.12e-06 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| HSPA5 | 14531 |
| DNAJB11 | 14528 |
| HYOU1 | 14527 |
| DNAJC3 | 14516 |
| DNAJB9 | 14510 |
| SYVN1 | 14485 |
| PDIA6 | 14482 |
| EDEM1 | 14479 |
| WFS1 | 14466 |
| GFPT1 | 14406 |
| MYDGF | 14306 |
| SERP1 | 14288 |
| WIPI1 | 14251 |
| SHC1 | 14209 |
| ATP6V0D1 | 14206 |
| SSR1 | 14205 |
| FKBP14 | 14184 |
| SRPRB | 14181 |
| ERN1 | 14152 |
| TSPYL2 | 14002 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HSPA5 | 14531 |
| DNAJB11 | 14528 |
| HYOU1 | 14527 |
| DNAJC3 | 14516 |
| DNAJB9 | 14510 |
| SYVN1 | 14485 |
| PDIA6 | 14482 |
| EDEM1 | 14479 |
| WFS1 | 14466 |
| GFPT1 | 14406 |
| MYDGF | 14306 |
| SERP1 | 14288 |
| WIPI1 | 14251 |
| SHC1 | 14209 |
| ATP6V0D1 | 14206 |
| SSR1 | 14205 |
| FKBP14 | 14184 |
| SRPRB | 14181 |
| ERN1 | 14152 |
| TSPYL2 | 14002 |
| HDGF | 13896 |
| TATDN2 | 13480 |
| TPP1 | 13378 |
| EXTL1 | 13312 |
| TLN1 | 12872 |
| CXXC1 | 12670 |
| ADD1 | 12538 |
| SEC31A | 12138 |
| DDX11 | 11907 |
| XBP1 | 11302 |
| PPP2R5B | 10834 |
| SRPRA | 10175 |
| CTDSP2 | 9444 |
| PLA2G4B | 8953 |
| CUL7 | 8310 |
| KLHDC3 | 8036 |
| ACADVL | 7903 |
| LMNA | 7854 |
| GSK3A | 7787 |
| EXTL3 | 6822 |
| ZBTB17 | 6703 |
| EXTL2 | 6440 |
| DCTN1 | 3338 |
| ARFGAP1 | 3224 |
| PREB | 2868 |
| GOSR2 | 2441 |
| SULT1A3 | 2038 |
| KDELR3 | 1922 |
| PDIA5 | 1130 |
| YIF1A | 381 |
Innate Immune System
| 520 | |
|---|---|
| set | Innate Immune System |
| setSize | 740 |
| pANOVA | 1.49e-08 |
| s.dist | 0.123 |
| p.adjustANOVA | 5.12e-06 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SERPING1 | 14532 |
| DNAJC3 | 14516 |
| HSP90B1 | 14514 |
| TXNIP | 14509 |
| MUC5B | 14487 |
| PLPP5 | 14436 |
| C1S | 14430 |
| ATP6V0B | 14422 |
| MAP3K8 | 14418 |
| C3 | 14417 |
| MAGT1 | 14398 |
| CFB | 14394 |
| CNN2 | 14383 |
| C4A | 14381 |
| C8B | 14372 |
| ERP44 | 14364 |
| FGA | 14346 |
| LAMP1 | 14314 |
| ATP6V0A1 | 14310 |
| LEAP2 | 14305 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SERPING1 | 14532 |
| DNAJC3 | 14516 |
| HSP90B1 | 14514 |
| TXNIP | 14509 |
| MUC5B | 14487 |
| PLPP5 | 14436 |
| C1S | 14430 |
| ATP6V0B | 14422 |
| MAP3K8 | 14418 |
| C3 | 14417 |
| MAGT1 | 14398 |
| CFB | 14394 |
| CNN2 | 14383 |
| C4A | 14381 |
| C8B | 14372 |
| ERP44 | 14364 |
| FGA | 14346 |
| LAMP1 | 14314 |
| ATP6V0A1 | 14310 |
| LEAP2 | 14305 |
| SERPINA3 | 14304 |
| CEACAM1 | 14302 |
| LAMP2 | 14291 |
| RNF125 | 14283 |
| POLR3GL | 14267 |
| CTSL | 14263 |
| ARSB | 14246 |
| GGH | 14243 |
| CCR6 | 14239 |
| LGALS3 | 14229 |
| ATP6V1D | 14228 |
| SHC1 | 14209 |
| ATP6V0D1 | 14206 |
| MLEC | 14193 |
| PLD1 | 14191 |
| C4B | 14173 |
| ATP6V0A2 | 14162 |
| S100A11 | 14143 |
| UBE2L6 | 14134 |
| TKFC | 14126 |
| P2RX1 | 14116 |
| GCA | 14108 |
| PLA2G2A | 14102 |
| BRI3 | 14094 |
| ACTG1 | 14090 |
| GNS | 14052 |
| PNP | 14046 |
| C8A | 14042 |
| NDUFC2 | 14038 |
| FGB | 14018 |
| C4BPB | 14006 |
| C5 | 14003 |
| CYSTM1 | 13982 |
| C1R | 13954 |
| NEU1 | 13953 |
| NFATC3 | 13947 |
| NHLRC3 | 13928 |
| VCP | 13902 |
| IRAK2 | 13893 |
| FTL | 13872 |
| PYGB | 13867 |
| PSMF1 | 13810 |
| ASAH1 | 13777 |
| ATP6V0E1 | 13731 |
| SURF4 | 13688 |
| TOLLIP | 13662 |
| NF2 | 13642 |
| WASL | 13611 |
| DUSP3 | 13608 |
| IGF2R | 13604 |
| FUCA2 | 13600 |
| DNM2 | 13597 |
| A1BG | 13591 |
| DNAJC5 | 13582 |
| CD55 | 13575 |
| TMBIM1 | 13533 |
| APP | 13532 |
| NFKBIB | 13495 |
| EP300 | 13485 |
| ALDOA | 13474 |
| MAPKAPK2 | 13468 |
| HEXB | 13459 |
| CLEC10A | 13452 |
| PSME4 | 13450 |
| DDX3X | 13448 |
| CD14 | 13442 |
| ICAM3 | 13436 |
| NFKBIA | 13427 |
| RAB37 | 13426 |
| PSMD2 | 13423 |
| DDOST | 13410 |
| CDK13 | 13387 |
| KCMF1 | 13357 |
| KPNB1 | 13324 |
| BCL2L1 | 13271 |
| UBR4 | 13266 |
| DSN1 | 13258 |
| MBL2 | 13247 |
| VTN | 13246 |
| ATAD3B | 13239 |
| PYCARD | 13221 |
| CFI | 13206 |
| GALNS | 13205 |
| SLC44A2 | 13182 |
| ICAM2 | 13167 |
| CTSA | 13149 |
| ALDH3B1 | 13143 |
| TAX1BP1 | 13141 |
| S100A1 | 13138 |
| ATP6V1E1 | 13114 |
| PRDX4 | 13105 |
| LCK | 13069 |
| MAP3K1 | 13035 |
| NPC2 | 12991 |
| TUBB4B | 12934 |
| ATF2 | 12933 |
| PGAM1 | 12932 |
| RAP2B | 12931 |
| CDA | 12891 |
| HP | 12884 |
| LRG1 | 12875 |
| C5AR1 | 12862 |
| SYNGR1 | 12842 |
| TMC6 | 12813 |
| FGG | 12809 |
| CD63 | 12800 |
| PTPRJ | 12791 |
| TAB1 | 12789 |
| PDXK | 12784 |
| ARPC4 | 12778 |
| ITCH | 12771 |
| ITPR3 | 12768 |
| ATP6V0C | 12764 |
| CYLD | 12727 |
| MASP1 | 12716 |
| DEGS1 | 12708 |
| IFIH1 | 12693 |
| MAPK3 | 12684 |
| MALT1 | 12658 |
| C6 | 12636 |
| COLEC11 | 12595 |
| DUSP4 | 12556 |
| PTPN6 | 12513 |
| PSMD6 | 12502 |
| IKBKG | 12493 |
| OTUD5 | 12487 |
| SRP14 | 12470 |
| MVP | 12465 |
| PRKCSH | 12463 |
| ATP6V1C2 | 12453 |
| CCT2 | 12444 |
| BPIFB1 | 12440 |
| BPIFB6 | 12439 |
| ARL8A | 12434 |
| MYO9B | 12432 |
| DDX41 | 12428 |
| DNM1 | 12417 |
| ITGB2 | 12388 |
| DOK3 | 12363 |
| CD68 | 12316 |
| CAPN1 | 12305 |
| ECSIT | 12282 |
| ANO6 | 12256 |
| RAB7A | 12220 |
| DIAPH1 | 12211 |
| PSMA2 | 12203 |
| RIPK2 | 12158 |
| MAPKAPK3 | 12147 |
| CFL1 | 12075 |
| ELK1 | 12060 |
| ITGAL | 12056 |
| PSMA1 | 12052 |
| ALAD | 12045 |
| WASF1 | 12021 |
| SNAP23 | 11956 |
| IQGAP1 | 11931 |
| NLRX1 | 11926 |
| DNASE1L1 | 11920 |
| CRK | 11901 |
| LTA4H | 11893 |
| GLA | 11875 |
| PRKCD | 11872 |
| PANX1 | 11867 |
| POLR3E | 11853 |
| CYFIP2 | 11850 |
| UBA7 | 11821 |
| CCT8 | 11813 |
| TRIM56 | 11765 |
| ATP6V1B2 | 11744 |
| PSMC1 | 11724 |
| ANXA2 | 11716 |
| RAF1 | 11708 |
| CASP10 | 11704 |
| AGA | 11701 |
| C6orf120 | 11690 |
| HRAS | 11673 |
| MAPK12 | 11663 |
| PSMD3 | 11655 |
| CASP1 | 11631 |
| CDC34 | 11619 |
| CD47 | 11617 |
| PRKCE | 11606 |
| PLA2G6 | 11578 |
| TRIM25 | 11574 |
| ISG15 | 11568 |
| CD4 | 11557 |
| PSME2 | 11555 |
| CD58 | 11554 |
| LRRFIP1 | 11545 |
| DHX58 | 11535 |
| POLR2L | 11530 |
| IDH1 | 11528 |
| PROS1 | 11519 |
| NCF2 | 11446 |
| BRK1 | 11428 |
| ATP8A1 | 11425 |
| FTH1 | 11406 |
| TRIM32 | 11376 |
| PSMD14 | 11371 |
| ALDOC | 11365 |
| POLR2K | 11350 |
| TXNDC5 | 11346 |
| PSTPIP1 | 11328 |
| MYD88 | 11305 |
| HLA-C | 11297 |
| ATP6V1G1 | 11283 |
| PSMD1 | 11280 |
| HGSNAT | 11261 |
| IQGAP2 | 11231 |
| ACTR3 | 11186 |
| RHOA | 11182 |
| MYO10 | 11171 |
| POLR2F | 11158 |
| ILF2 | 11108 |
| CASP9 | 11084 |
| PELI1 | 11028 |
| PIK3C3 | 11026 |
| PSAP | 11023 |
| CTSB | 10996 |
| CEP290 | 10987 |
| HLA-A | 10971 |
| ACTR1B | 10947 |
| MIF | 10935 |
| FOS | 10931 |
| MASP2 | 10923 |
| TBK1 | 10919 |
| PPP2CA | 10917 |
| PKM | 10849 |
| LBP | 10799 |
| ATP6V0E2 | 10798 |
| SLCO4C1 | 10785 |
| CTSH | 10743 |
| AAMP | 10725 |
| CLU | 10723 |
| UBA52 | 10707 |
| MAPK1 | 10705 |
| ACTB | 10683 |
| EEF2 | 10659 |
| NIT2 | 10636 |
| ACTR10 | 10590 |
| CFD | 10570 |
| VNN1 | 10554 |
| HMGB1 | 10552 |
| POLR1C | 10515 |
| VAMP8 | 10475 |
| BPIFB2 | 10473 |
| PAK2 | 10458 |
| CAB39 | 10457 |
| ATP6V1C1 | 10444 |
| PSMB9 | 10430 |
| PSEN1 | 10427 |
| ATF1 | 10407 |
| NCKIPSD | 10395 |
| GPI | 10361 |
| NOS3 | 10359 |
| ATG7 | 10354 |
| NOD1 | 10348 |
| VAPA | 10346 |
| PSMB6 | 10326 |
| PFKL | 10325 |
| PSMC6 | 10307 |
| RAB31 | 10305 |
| CAPZA1 | 10272 |
| GSDMD | 10266 |
| OSTF1 | 10254 |
| CTSK | 10213 |
| PSMC4 | 10196 |
| TBC1D10C | 10190 |
| DSP | 10069 |
| PPP2R1A | 10064 |
| DERA | 10063 |
| HMOX2 | 10061 |
| MYH9 | 10036 |
| GM2A | 9989 |
| GLIPR1 | 9959 |
| CD36 | 9953 |
| POLR2E | 9916 |
| UBE2V1 | 9900 |
| HSPA8 | 9895 |
| C4BPA | 9865 |
| VAV3 | 9861 |
| FAF2 | 9859 |
| PSMD9 | 9853 |
| RBSN | 9844 |
| TSPAN14 | 9825 |
| TANK | 9817 |
| PGM1 | 9783 |
| NKIRAS2 | 9777 |
| LPCAT1 | 9761 |
| OSCAR | 9699 |
| TUBB | 9694 |
| PSMD5 | 9676 |
| PPP2CB | 9606 |
| POLR1D | 9588 |
| SOCS1 | 9561 |
| MAP2K4 | 9558 |
| VAT1 | 9540 |
| ALPK1 | 9538 |
| ORMDL3 | 9537 |
| CD46 | 9531 |
| PELI3 | 9505 |
| CAT | 9504 |
| ABI1 | 9492 |
| BCL10 | 9472 |
| COMMD3 | 9446 |
| NLRC5 | 9432 |
| CTSC | 9398 |
| PPIA | 9393 |
| ARPC1B | 9372 |
| PSMD7 | 9371 |
| HSP90AB1 | 9363 |
| ATP6V1H | 9358 |
| PSMD10 | 9356 |
| MAP2K7 | 9311 |
| IMPDH2 | 9308 |
| PYGL | 9295 |
| EPPIN | 9281 |
| MAPK7 | 9270 |
| PIK3R1 | 9259 |
| PSMB7 | 9253 |
| AHCYL1 | 9245 |
| PTK2 | 9198 |
| UBE2M | 9174 |
| MUC15 | 9153 |
| ITPR1 | 9146 |
| ITGAV | 9120 |
| AGPAT2 | 9047 |
| UBB | 9013 |
| C7 | 9004 |
| NFATC2 | 8958 |
| TRIM4 | 8937 |
| PLEKHO2 | 8935 |
| APEH | 8922 |
| GAA | 8919 |
| PSMA4 | 8902 |
| ANPEP | 8901 |
| TOM1 | 8877 |
| ARG1 | 8835 |
| PPP3R1 | 8832 |
| YPEL5 | 8825 |
| XRCC5 | 8806 |
| PPP2R1B | 8759 |
| EEF1A1 | 8740 |
| DPP7 | 8739 |
| CUL1 | 8725 |
| GAB2 | 8722 |
| HMOX1 | 8715 |
| MAP2K1 | 8704 |
| DHX9 | 8688 |
| PSMD4 | 8670 |
| COPB1 | 8664 |
| ACLY | 8659 |
| LCN2 | 8658 |
| PSMC5 | 8646 |
| ATP6V1B1 | 8635 |
| CAP1 | 8634 |
| PPP3CB | 8574 |
| PTAFR | 8514 |
| PLAUR | 8513 |
| POLR3D | 8453 |
| UBE2D3 | 8449 |
| TIRAP | 8439 |
| CNPY3 | 8413 |
| NME2 | 8403 |
| ORM1 | 8400 |
| SARM1 | 8374 |
| CSNK2B | 8368 |
| VCL | 8357 |
| CKAP4 | 8327 |
| SIKE1 | 8322 |
| TIMP2 | 8320 |
| METTL7A | 8298 |
| TNFAIP3 | 8284 |
| TTR | 8283 |
| CPB2 | 8234 |
| CREBBP | 8214 |
| TAB2 | 8201 |
| DUSP7 | 8185 |
| RAB3A | 8176 |
| PSMD12 | 8163 |
| RPS6KA1 | 8159 |
| C2 | 8098 |
| RNF216 | 8077 |
| PSME3 | 8052 |
| CASP2 | 7990 |
| FBXW11 | 7986 |
| HLA-H | 7975 |
| ATP6V1A | 7965 |
| HUWE1 | 7955 |
| PLCG2 | 7942 |
| CPNE1 | 7836 |
| LAT | 7813 |
| NLRC4 | 7799 |
| TRIM21 | 7792 |
| MRE11 | 7780 |
| NBEAL2 | 7749 |
| PDAP1 | 7739 |
| PLD2 | 7673 |
| CPN1 | 7658 |
| DYNC1H1 | 7639 |
| RAB24 | 7638 |
| FABP5 | 7635 |
| TXN | 7626 |
| SERPINA1 | 7622 |
| ROCK1 | 7591 |
| POLR2H | 7590 |
| TMEM179B | 7543 |
| SRC | 7516 |
| SIRPA | 7474 |
| COMMD9 | 7455 |
| NFKB1 | 7409 |
| MYO5A | 7394 |
| AP2A2 | 7391 |
| ACAA1 | 7384 |
| HVCN1 | 7380 |
| DYNLT1 | 7253 |
| LYZ | 7247 |
| ARPC3 | 7237 |
| GOLGA7 | 7208 |
| MAP3K7 | 7172 |
| DUSP6 | 7113 |
| CST3 | 7101 |
| WASF2 | 7096 |
| CHUK | 7086 |
| STBD1 | 7077 |
| HSPA6 | 7061 |
| MAP2K3 | 7038 |
| ATG12 | 7022 |
| ATOX1 | 6974 |
| MEF2A | 6959 |
| RAB14 | 6952 |
| PTGES2 | 6882 |
| TIFA | 6848 |
| RAP1B | 6830 |
| CD59 | 6818 |
| MANBA | 6817 |
| DOCK1 | 6760 |
| SLC11A1 | 6739 |
| UBE2D1 | 6734 |
| C5AR2 | 6671 |
| BIRC3 | 6654 |
| HEBP2 | 6631 |
| PA2G4 | 6585 |
| SEM1 | 6566 |
| RAB5C | 6565 |
| APRT | 6499 |
| PDZD11 | 6494 |
| DBNL | 6490 |
| TMEM63A | 6449 |
| PSMA3 | 6422 |
| CPNE3 | 6354 |
| GRB2 | 6346 |
| LYN | 6328 |
| RPS6KA3 | 6316 |
| LAIR1 | 6304 |
| CTNNB1 | 6288 |
| SLC2A5 | 6243 |
| WIPF2 | 6174 |
| APOB | 6172 |
| PLAU | 6169 |
| TMEM30A | 6157 |
| RAB4B | 6116 |
| JUN | 6103 |
| IKBKB | 6100 |
| PSMD8 | 6091 |
| CASP8 | 6085 |
| POLR3K | 6076 |
| RIPK1 | 6000 |
| TRAPPC1 | 5956 |
| RPS6KA5 | 5949 |
| PIN1 | 5922 |
| STK11IP | 5898 |
| DTX4 | 5869 |
| PIK3CA | 5849 |
| GRN | 5836 |
| ARPC1A | 5822 |
| TOMM70 | 5819 |
| RAB27A | 5804 |
| NCKAP1 | 5794 |
| ELMO1 | 5782 |
| RPS27A | 5776 |
| EEA1 | 5759 |
| RHOG | 5747 |
| MAPK10 | 5681 |
| PSMA5 | 5657 |
| ATG5 | 5644 |
| AP1M1 | 5637 |
| RAB5B | 5611 |
| ARSA | 5552 |
| ADAM10 | 5549 |
| BST2 | 5531 |
| S100P | 5511 |
| RELA | 5468 |
| LAMTOR3 | 5467 |
| VAV2 | 5425 |
| CTSD | 5416 |
| RHOF | 5403 |
| PIK3CB | 5379 |
| PSMD13 | 5353 |
| MAP3K14 | 5349 |
| HLA-B | 5329 |
| B2M | 5242 |
| DYNC1LI1 | 5237 |
| FUCA1 | 5210 |
| POLR3H | 5168 |
| CPPED1 | 5138 |
| SERPINB6 | 5125 |
| WASF3 | 5070 |
| ATP11B | 5015 |
| QPCT | 5009 |
| CANT1 | 4969 |
| TAB3 | 4960 |
| PSMC2 | 4948 |
| TLR9 | 4913 |
| PLAC8 | 4886 |
| MAP2K6 | 4868 |
| PSME1 | 4861 |
| PLCG1 | 4855 |
| DYNLL1 | 4853 |
| HTN3 | 4834 |
| PRKDC | 4777 |
| MEFV | 4758 |
| PRCP | 4730 |
| POLR3B | 4721 |
| SLC15A4 | 4647 |
| PTPN4 | 4643 |
| ARMC8 | 4638 |
| SPTAN1 | 4610 |
| IRAK1 | 4593 |
| C8G | 4585 |
| ARPC2 | 4575 |
| CARD9 | 4496 |
| CDC42 | 4489 |
| ARHGAP9 | 4486 |
| JUP | 4478 |
| MGST1 | 4472 |
| NRAS | 4465 |
| MAPK14 | 4391 |
| PPP2R5D | 4385 |
| ITPR2 | 4366 |
| CYBA | 4283 |
| CRISPLD2 | 4273 |
| KLRK1 | 4247 |
| SERPINB1 | 4239 |
| SVIP | 4238 |
| AGER | 4235 |
| AGL | 4233 |
| POLR3A | 4231 |
| KRAS | 4210 |
| CTSV | 4202 |
| KLRD1 | 4192 |
| GDI2 | 4162 |
| ATP7A | 4123 |
| IST1 | 4111 |
| TICAM1 | 4022 |
| ABL1 | 3944 |
| PSMB3 | 3928 |
| PTPRN2 | 3851 |
| MAPK13 | 3846 |
| UNC13D | 3835 |
| PELI2 | 3834 |
| CYFIP1 | 3785 |
| FYN | 3783 |
| BCL2 | 3762 |
| ITGAX | 3756 |
| SDCBP | 3724 |
| FADD | 3704 |
| IMPDH1 | 3690 |
| CLEC7A | 3685 |
| PSMB2 | 3678 |
| HERC5 | 3641 |
| UBE2N | 3604 |
| HSPA1A | 3603 |
| SCAMP1 | 3566 |
| POLR3C | 3531 |
| MAPK9 | 3449 |
| PRKACA | 3407 |
| CAND1 | 3381 |
| MAVS | 3323 |
| HTN1 | 3309 |
| SUGT1 | 3265 |
| RAB10 | 3205 |
| RAB3D | 3155 |
| TRAF6 | 3150 |
| CAPZA2 | 3143 |
| IRAK4 | 3137 |
| STAT6 | 3128 |
| SLC2A3 | 3116 |
| MUC13 | 3097 |
| STOM | 3093 |
| LIMK1 | 3082 |
| ARPC5 | 3073 |
| PSMC3 | 3070 |
| GLB1 | 3064 |
| POLR3G | 3049 |
| NCK1 | 3010 |
| SIGIRR | 2961 |
| CTSS | 2960 |
| GSN | 2952 |
| ATP11A | 2935 |
| CXCR2 | 2899 |
| PRKACB | 2885 |
| ACTR2 | 2855 |
| ADGRG3 | 2825 |
| BTRC | 2757 |
| PIK3R2 | 2728 |
| YES1 | 2690 |
| LY96 | 2689 |
| MOSPD2 | 2673 |
| PPIE | 2651 |
| TNIP2 | 2640 |
| NFKB2 | 2634 |
| RAB6A | 2578 |
| VRK3 | 2573 |
| UBA3 | 2562 |
| APAF1 | 2532 |
| QSOX1 | 2518 |
| ATP6AP2 | 2508 |
| ORM2 | 2502 |
| GUSB | 2493 |
| MYO1C | 2457 |
| PLD3 | 2446 |
| ABI2 | 2431 |
| ADAM8 | 2424 |
| GYG1 | 2373 |
| RPS6KA2 | 2339 |
| PSMB4 | 2330 |
| ITK | 2265 |
| RAP2C | 2257 |
| PIK3R4 | 2219 |
| TLR6 | 2218 |
| SIRPB1 | 2169 |
| PECAM1 | 2152 |
| HSP90AA1 | 2096 |
| MUC20 | 2082 |
| PSMB1 | 2062 |
| PAK1 | 2021 |
| NCKAP1L | 1980 |
| LGMN | 1966 |
| NAPRT | 1945 |
| CRCP | 1930 |
| SOS1 | 1928 |
| PCBP2 | 1919 |
| DDX58 | 1883 |
| UBE2D2 | 1857 |
| ELMO2 | 1854 |
| PSMA7 | 1820 |
| COTL1 | 1794 |
| ATP6V1F | 1771 |
| PTPN11 | 1770 |
| IRF3 | 1694 |
| AMPD3 | 1688 |
| GHDC | 1682 |
| SLC27A2 | 1635 |
| IKBKE | 1593 |
| LAMTOR1 | 1557 |
| UBC | 1551 |
| CSTB | 1547 |
| ATP6V0D2 | 1494 |
| PSMB5 | 1484 |
| SNAP29 | 1422 |
| RNASET2 | 1419 |
| MAPK8 | 1418 |
| BST1 | 1408 |
| NOS1 | 1403 |
| DNAJC13 | 1370 |
| ATP6V1G2 | 1360 |
| POLR3F | 1355 |
| CALM1 | 1340 |
| KCNAB2 | 1323 |
| LAT2 | 1316 |
| BAIAP2 | 1295 |
| F2 | 1246 |
| MAN2B1 | 1230 |
| TRAF2 | 1180 |
| FRK | 1179 |
| CYB5R3 | 1177 |
| DHX36 | 1159 |
| CCL22 | 1142 |
| NCSTN | 1137 |
| SKP1 | 1117 |
| ATP6V1E2 | 1090 |
| UNC93B1 | 1053 |
| BIRC2 | 1007 |
| CD19 | 954 |
| PAFAH1B2 | 953 |
| RELB | 951 |
| CREB1 | 935 |
| PSMD11 | 879 |
| PSMB10 | 838 |
| PDPK1 | 782 |
| RAB18 | 760 |
| UBE2K | 750 |
| PPP3CA | 748 |
| FCER1G | 746 |
| TRAF3 | 729 |
| ADGRE5 | 651 |
| STK10 | 642 |
| RAP1A | 604 |
| B4GALT1 | 540 |
| CMTM6 | 535 |
| PGM2 | 513 |
| PGRMC1 | 498 |
| MAPK11 | 492 |
| GMFG | 450 |
| CASP4 | 379 |
| TCIRG1 | 348 |
| LAMTOR2 | 299 |
| NKIRAS1 | 298 |
| NLRP1 | 269 |
| PSMA6 | 261 |
| RNF135 | 247 |
| DGAT1 | 222 |
| CPN2 | 221 |
| CRACR2A | 155 |
| PRDX6 | 106 |
| RAC1 | 95 |
| CREG1 | 87 |
| XRCC6 | 67 |
| AHSG | 62 |
Cholesterol biosynthesis
| 162 | |
|---|---|
| set | Cholesterol biosynthesis |
| setSize | 24 |
| pANOVA | 2.32e-08 |
| s.dist | 0.659 |
| p.adjustANOVA | 6.4e-06 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MSMO1 | 14517 |
| HMGCS1 | 14473 |
| SQLE | 14468 |
| IDI1 | 14452 |
| HMGCR | 14408 |
| MVK | 14363 |
| DHCR7 | 14319 |
| MVD | 14220 |
| FDFT1 | 14189 |
| LSS | 14165 |
| ACAT2 | 13351 |
| ARV1 | 13201 |
| FDPS | 12999 |
| CYP51A1 | 12901 |
| TM7SF2 | 12785 |
| NSDHL | 11890 |
| DHCR24 | 11041 |
| GGPS1 | 10498 |
| SC5D | 10071 |
| EBP | 9739 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MSMO1 | 14517 |
| HMGCS1 | 14473 |
| SQLE | 14468 |
| IDI1 | 14452 |
| HMGCR | 14408 |
| MVK | 14363 |
| DHCR7 | 14319 |
| MVD | 14220 |
| FDFT1 | 14189 |
| LSS | 14165 |
| ACAT2 | 13351 |
| ARV1 | 13201 |
| FDPS | 12999 |
| CYP51A1 | 12901 |
| TM7SF2 | 12785 |
| NSDHL | 11890 |
| DHCR24 | 11041 |
| GGPS1 | 10498 |
| SC5D | 10071 |
| EBP | 9739 |
| PLPP6 | 8931 |
| LBR | 6666 |
| PMVK | 6407 |
| HSD17B7 | 5017 |
Regulation of cholesterol biosynthesis by SREBP (SREBF)
| 977 | |
|---|---|
| set | Regulation of cholesterol biosynthesis by SREBP (SREBF) |
| setSize | 54 |
| pANOVA | 5.07e-08 |
| s.dist | 0.429 |
| p.adjustANOVA | 1.16e-05 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SEC24D | 14520 |
| HMGCS1 | 14473 |
| SQLE | 14468 |
| IDI1 | 14452 |
| HMGCR | 14408 |
| MVK | 14363 |
| DHCR7 | 14319 |
| SREBF2 | 14223 |
| MVD | 14220 |
| FDFT1 | 14189 |
| LSS | 14165 |
| ELOVL6 | 14093 |
| SEC24A | 14088 |
| NCOA6 | 13941 |
| PPARA | 13906 |
| RAN | 13497 |
| SCD | 13413 |
| GPAM | 13366 |
| KPNB1 | 13324 |
| SEC24C | 13047 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SEC24D | 14520 |
| HMGCS1 | 14473 |
| SQLE | 14468 |
| IDI1 | 14452 |
| HMGCR | 14408 |
| MVK | 14363 |
| DHCR7 | 14319 |
| SREBF2 | 14223 |
| MVD | 14220 |
| FDFT1 | 14189 |
| LSS | 14165 |
| ELOVL6 | 14093 |
| SEC24A | 14088 |
| NCOA6 | 13941 |
| PPARA | 13906 |
| RAN | 13497 |
| SCD | 13413 |
| GPAM | 13366 |
| KPNB1 | 13324 |
| SEC24C | 13047 |
| FDPS | 12999 |
| CYP51A1 | 12901 |
| TM7SF2 | 12785 |
| MBTPS1 | 12523 |
| INSIG2 | 12407 |
| SCAP | 11960 |
| SEC24B | 11541 |
| ACACB | 11531 |
| MED1 | 11468 |
| SP1 | 11396 |
| GGPS1 | 10498 |
| SC5D | 10071 |
| NCOA1 | 9914 |
| CHD9 | 9842 |
| NFYB | 9634 |
| HELZ2 | 9086 |
| NCOA2 | 9072 |
| RXRA | 8607 |
| MTF1 | 8354 |
| CREBBP | 8214 |
| SREBF1 | 7517 |
| MBTPS2 | 7019 |
| CARM1 | 6725 |
| PMVK | 6407 |
| SAR1B | 6198 |
| SEC23A | 5659 |
| NFYA | 5142 |
| SMARCD3 | 4455 |
| TGS1 | 4181 |
| FASN | 3698 |
| TBL1X | 3308 |
| TBL1XR1 | 2795 |
| NFYC | 1395 |
| ACACA | 236 |
XBP1(S) activates chaperone genes
| 1341 | |
|---|---|
| set | XBP1(S) activates chaperone genes |
| setSize | 48 |
| pANOVA | 1.21e-07 |
| s.dist | 0.442 |
| p.adjustANOVA | 2.21e-05 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| DNAJB11 | 14528 |
| HYOU1 | 14527 |
| DNAJC3 | 14516 |
| DNAJB9 | 14510 |
| SYVN1 | 14485 |
| PDIA6 | 14482 |
| EDEM1 | 14479 |
| WFS1 | 14466 |
| GFPT1 | 14406 |
| MYDGF | 14306 |
| SERP1 | 14288 |
| WIPI1 | 14251 |
| SHC1 | 14209 |
| ATP6V0D1 | 14206 |
| SSR1 | 14205 |
| FKBP14 | 14184 |
| SRPRB | 14181 |
| TSPYL2 | 14002 |
| HDGF | 13896 |
| TATDN2 | 13480 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| DNAJB11 | 14528 |
| HYOU1 | 14527 |
| DNAJC3 | 14516 |
| DNAJB9 | 14510 |
| SYVN1 | 14485 |
| PDIA6 | 14482 |
| EDEM1 | 14479 |
| WFS1 | 14466 |
| GFPT1 | 14406 |
| MYDGF | 14306 |
| SERP1 | 14288 |
| WIPI1 | 14251 |
| SHC1 | 14209 |
| ATP6V0D1 | 14206 |
| SSR1 | 14205 |
| FKBP14 | 14184 |
| SRPRB | 14181 |
| TSPYL2 | 14002 |
| HDGF | 13896 |
| TATDN2 | 13480 |
| TPP1 | 13378 |
| EXTL1 | 13312 |
| TLN1 | 12872 |
| CXXC1 | 12670 |
| ADD1 | 12538 |
| SEC31A | 12138 |
| DDX11 | 11907 |
| XBP1 | 11302 |
| PPP2R5B | 10834 |
| SRPRA | 10175 |
| CTDSP2 | 9444 |
| PLA2G4B | 8953 |
| CUL7 | 8310 |
| KLHDC3 | 8036 |
| ACADVL | 7903 |
| LMNA | 7854 |
| GSK3A | 7787 |
| EXTL3 | 6822 |
| ZBTB17 | 6703 |
| EXTL2 | 6440 |
| DCTN1 | 3338 |
| ARFGAP1 | 3224 |
| PREB | 2868 |
| GOSR2 | 2441 |
| SULT1A3 | 2038 |
| KDELR3 | 1922 |
| PDIA5 | 1130 |
| YIF1A | 381 |
Signal Transduction
| 1072 | |
|---|---|
| set | Signal Transduction |
| setSize | 1748 |
| pANOVA | 1.28e-07 |
| s.dist | 0.0777 |
| p.adjustANOVA | 2.21e-05 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SEL1L | 14508 |
| KNG1 | 14503 |
| ATP2A2 | 14500 |
| PLG | 14495 |
| MTMR4 | 14488 |
| SYVN1 | 14485 |
| IGF2 | 14477 |
| SOCS3 | 14476 |
| ACTA2 | 14438 |
| TMED2 | 14433 |
| ATP6V0B | 14422 |
| ARRB1 | 14420 |
| C3 | 14417 |
| PGF | 14409 |
| DERL2 | 14399 |
| COL9A2 | 14389 |
| RAMP1 | 14385 |
| SHB | 14382 |
| CX3CL1 | 14375 |
| RUNX1 | 14359 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SEL1L | 14508 |
| KNG1 | 14503 |
| ATP2A2 | 14500 |
| PLG | 14495 |
| MTMR4 | 14488 |
| SYVN1 | 14485 |
| IGF2 | 14477 |
| SOCS3 | 14476 |
| ACTA2 | 14438 |
| TMED2 | 14433 |
| ATP6V0B | 14422 |
| ARRB1 | 14420 |
| C3 | 14417 |
| PGF | 14409 |
| DERL2 | 14399 |
| COL9A2 | 14389 |
| RAMP1 | 14385 |
| SHB | 14382 |
| CX3CL1 | 14375 |
| RUNX1 | 14359 |
| SQSTM1 | 14347 |
| FGA | 14346 |
| RRAGC | 14345 |
| STEAP3 | 14327 |
| GPER1 | 14326 |
| OS9 | 14320 |
| ADH4 | 14312 |
| ATP6V0A1 | 14310 |
| ARHGEF2 | 14307 |
| PEBP1 | 14300 |
| RHOQ | 14296 |
| JAK3 | 14295 |
| DVL3 | 14293 |
| TFF3 | 14289 |
| COL6A1 | 14284 |
| AMOTL2 | 14282 |
| PIK3AP1 | 14273 |
| JAG1 | 14259 |
| TGFB1 | 14241 |
| CCR6 | 14239 |
| F2RL1 | 14234 |
| BCAR1 | 14233 |
| ARHGEF28 | 14232 |
| ATP6V1D | 14228 |
| SHC1 | 14209 |
| ATP6V0D1 | 14206 |
| CDH1 | 14202 |
| ARHGAP32 | 14201 |
| PLD1 | 14191 |
| MAML1 | 14179 |
| CCL20 | 14171 |
| P4HB | 14170 |
| ATP6V0A2 | 14162 |
| MET | 14159 |
| RANBP9 | 14151 |
| RHOBTB2 | 14141 |
| VGF | 14140 |
| EPHA2 | 14124 |
| HES1 | 14121 |
| SFPQ | 14118 |
| DAGLA | 14113 |
| ACTG1 | 14090 |
| GOLGA3 | 14085 |
| FLNA | 14081 |
| HNRNPM | 14075 |
| BCL9L | 14074 |
| PDGFRB | 14062 |
| SEC13 | 14049 |
| NEDD4L | 14037 |
| ST3GAL4 | 14033 |
| TRIB3 | 14029 |
| CDK1 | 14027 |
| BEX3 | 14021 |
| FGB | 14018 |
| C5 | 14003 |
| PPP1R15A | 13999 |
| RHOC | 13943 |
| RRAGD | 13938 |
| PTPN3 | 13930 |
| HNRNPF | 13925 |
| FLRT3 | 13907 |
| VCP | 13902 |
| RAPGEF2 | 13897 |
| THBS4 | 13862 |
| FURIN | 13851 |
| NDC80 | 13840 |
| FOSL1 | 13826 |
| ACTN1 | 13824 |
| COL9A3 | 13817 |
| DDX5 | 13814 |
| FLOT2 | 13811 |
| PSMF1 | 13810 |
| NUDC | 13808 |
| EMC3 | 13805 |
| MYL12B | 13785 |
| CTNND1 | 13781 |
| TNFRSF10B | 13770 |
| RHOBTB3 | 13761 |
| TFRC | 13755 |
| KIF5A | 13752 |
| ATP6V0E1 | 13731 |
| SOX9 | 13716 |
| LMNB1 | 13707 |
| NUP37 | 13706 |
| AKAP13 | 13699 |
| DLC1 | 13698 |
| E2F1 | 13694 |
| GNA13 | 13689 |
| TUBA1B | 13681 |
| RAPGEF1 | 13680 |
| PRKCZ | 13676 |
| AGT | 13674 |
| VEGFB | 13646 |
| NF2 | 13642 |
| TCF7 | 13636 |
| MC1R | 13634 |
| CPT1A | 13626 |
| RALA | 13623 |
| KNL1 | 13621 |
| MAD2L1 | 13616 |
| WASL | 13611 |
| DUSP3 | 13608 |
| NGEF | 13605 |
| ESYT1 | 13601 |
| DNM2 | 13597 |
| VRK2 | 13580 |
| SEMA4F | 13579 |
| CD55 | 13575 |
| F11R | 13568 |
| ANKLE2 | 13567 |
| APP | 13532 |
| VHL | 13531 |
| FGD3 | 13525 |
| CENPK | 13518 |
| TLE4 | 13500 |
| SPC24 | 13498 |
| ANKRD26 | 13489 |
| EP300 | 13485 |
| NUF2 | 13470 |
| MAPKAPK2 | 13468 |
| PSME4 | 13450 |
| ARHGAP35 | 13445 |
| RXFP4 | 13440 |
| CLTA | 13432 |
| BUB1B | 13431 |
| NFKBIA | 13427 |
| PSMD2 | 13423 |
| ADRA2C | 13422 |
| SCD | 13413 |
| CAMKK1 | 13397 |
| P2RY11 | 13374 |
| GPAM | 13366 |
| PDE4D | 13364 |
| TMPO | 13363 |
| EEF2K | 13359 |
| CBX2 | 13350 |
| POGLUT1 | 13337 |
| CBFB | 13329 |
| MYL6 | 13325 |
| KDM3A | 13323 |
| NAB2 | 13315 |
| FNBP1 | 13314 |
| TMEM59 | 13311 |
| MIS12 | 13304 |
| SALL4 | 13298 |
| HEBP1 | 13295 |
| IQGAP3 | 13282 |
| LPAR6 | 13275 |
| BCL2L1 | 13271 |
| CDC42EP4 | 13265 |
| PDGFB | 13263 |
| DSN1 | 13258 |
| BAIAP2L1 | 13253 |
| PIP4K2C | 13241 |
| DNAJB1 | 13228 |
| AURKB | 13190 |
| ARHGAP39 | 13184 |
| PFN2 | 13179 |
| ABHD12 | 13159 |
| PFN1 | 13146 |
| FNTA | 13142 |
| TAX1BP1 | 13141 |
| LRIG1 | 13140 |
| CPD | 13139 |
| GNA12 | 13131 |
| PTPN18 | 13128 |
| MAML2 | 13122 |
| KLHL12 | 13118 |
| ATP6V1E1 | 13114 |
| RARA | 13109 |
| OCRL | 13103 |
| RPGRIP1L | 13101 |
| KMT2D | 13087 |
| PDK2 | 13086 |
| CDC25C | 13084 |
| NCBP2 | 13081 |
| HPN | 13075 |
| KDM4A | 13073 |
| LCK | 13069 |
| MAPK6 | 13068 |
| ZNF217 | 13059 |
| RBBP6 | 13058 |
| FGFR2 | 13048 |
| ATP6AP1 | 13046 |
| PTK2B | 13043 |
| SMURF1 | 13034 |
| CLTC | 13017 |
| FZD9 | 13007 |
| SH3RF1 | 13005 |
| NOTUM | 12998 |
| DGKZ | 12992 |
| ITGA2 | 12988 |
| PTPRK | 12980 |
| PTGDR2 | 12978 |
| GNG10 | 12977 |
| SPEN | 12976 |
| PLCB1 | 12974 |
| SRGAP3 | 12970 |
| KBTBD7 | 12967 |
| PRDM4 | 12965 |
| FGFR1 | 12960 |
| EDN1 | 12955 |
| ABHD17A | 12949 |
| ATF2 | 12933 |
| GREB1 | 12928 |
| ERLEC1 | 12918 |
| PARD3 | 12914 |
| MFNG | 12905 |
| ARHGAP19 | 12886 |
| FGFBP3 | 12881 |
| TLN1 | 12872 |
| SMAD3 | 12871 |
| SHMT2 | 12864 |
| C5AR1 | 12862 |
| SPDL1 | 12856 |
| RDH10 | 12847 |
| BCAP31 | 12840 |
| DAB2IP | 12838 |
| HGFAC | 12835 |
| BAD | 12822 |
| FGG | 12809 |
| COL4A5 | 12804 |
| PTPRJ | 12791 |
| TAB1 | 12789 |
| LATS2 | 12786 |
| ARPC4 | 12778 |
| FOSB | 12773 |
| ITCH | 12771 |
| ITPR3 | 12768 |
| OPN3 | 12767 |
| MAP2K2 | 12766 |
| ATP6V0C | 12764 |
| KNTC1 | 12758 |
| ADM2 | 12730 |
| STRADA | 12729 |
| CYLD | 12727 |
| SCMH1 | 12722 |
| CLTB | 12719 |
| KIDINS220 | 12710 |
| CDCA8 | 12700 |
| MYLIP | 12695 |
| MAPK3 | 12684 |
| PTHLH | 12681 |
| LAMA5 | 12680 |
| PTBP1 | 12672 |
| CKAP5 | 12651 |
| STARD13 | 12646 |
| RAB9A | 12633 |
| PDE6D | 12619 |
| DNAL4 | 12616 |
| ABCG5 | 12609 |
| MEF2D | 12594 |
| RHPN1 | 12589 |
| MFN2 | 12586 |
| DDRGK1 | 12585 |
| AKT1S1 | 12584 |
| RRAD | 12580 |
| DGKE | 12576 |
| AGO4 | 12561 |
| DUSP4 | 12556 |
| SLC1A5 | 12542 |
| STAT5B | 12541 |
| TAS2R5 | 12532 |
| RGS5 | 12517 |
| PTPN6 | 12513 |
| RASGRF2 | 12510 |
| ZDHHC7 | 12508 |
| SSTR3 | 12506 |
| PSMD6 | 12502 |
| PRC1 | 12500 |
| CLIP1 | 12494 |
| IKBKG | 12493 |
| LETM1 | 12482 |
| FZD4 | 12474 |
| OPRL1 | 12469 |
| CDC42BPA | 12468 |
| MAPKAP1 | 12466 |
| SPATA13 | 12459 |
| PCK1 | 12455 |
| ATP6V1C2 | 12453 |
| CCT2 | 12444 |
| BCL9 | 12441 |
| MYO9B | 12432 |
| GNA11 | 12425 |
| SKA2 | 12421 |
| DNM1 | 12417 |
| EIF4G1 | 12400 |
| USF2 | 12399 |
| EIF4B | 12396 |
| ZRANB1 | 12391 |
| SIN3A | 12373 |
| SPP1 | 12355 |
| CCT6A | 12336 |
| CXXC5 | 12331 |
| ARHGEF40 | 12329 |
| DHRS4 | 12312 |
| RGL3 | 12308 |
| MEMO1 | 12288 |
| UBXN11 | 12284 |
| HTR7 | 12283 |
| ADAM17 | 12276 |
| RTKN | 12273 |
| MKS1 | 12242 |
| KIF2A | 12231 |
| MTA3 | 12223 |
| RAB7A | 12220 |
| MOV10 | 12217 |
| FKBP4 | 12213 |
| DIAPH1 | 12211 |
| PDE3A | 12209 |
| AGO3 | 12205 |
| PSMA2 | 12203 |
| ITGB3BP | 12199 |
| LIMK2 | 12193 |
| WHAMM | 12191 |
| FGD4 | 12166 |
| CXCL16 | 12165 |
| RIPK2 | 12158 |
| DYNC2H1 | 12153 |
| MAPKAPK3 | 12147 |
| RDH11 | 12131 |
| AXIN2 | 12097 |
| ZNRF3 | 12093 |
| OPHN1 | 12089 |
| PPP2R5A | 12088 |
| CFL1 | 12075 |
| PPM1A | 12067 |
| ELK1 | 12060 |
| NET1 | 12058 |
| PSMA1 | 12052 |
| ADCY7 | 12040 |
| FZD6 | 12029 |
| TIA1 | 12027 |
| WASF1 | 12021 |
| RCC2 | 12011 |
| CBL | 12008 |
| MAF1 | 11999 |
| RAMP2 | 11990 |
| PTCH2 | 11989 |
| TOR1AIP1 | 11985 |
| MKRN1 | 11981 |
| PLXND1 | 11963 |
| SNAP23 | 11956 |
| STAT1 | 11938 |
| SOWAHC | 11934 |
| IQGAP1 | 11931 |
| NDEL1 | 11904 |
| CRK | 11901 |
| ZWILCH | 11891 |
| DLG5 | 11889 |
| CENPH | 11884 |
| ADH1A | 11878 |
| PRKCD | 11872 |
| NOTCH2 | 11869 |
| ARHGAP42 | 11866 |
| EZH2 | 11860 |
| HINT2 | 11856 |
| TJP2 | 11851 |
| CYFIP2 | 11850 |
| MTA2 | 11843 |
| YBX1 | 11834 |
| KIF7 | 11828 |
| CCP110 | 11807 |
| EFCAB7 | 11806 |
| RGL1 | 11795 |
| ABHD17C | 11785 |
| RNF41 | 11780 |
| ECE1 | 11768 |
| GIT1 | 11767 |
| SNW1 | 11762 |
| ATP6V1B2 | 11744 |
| APH1B | 11741 |
| DUSP5 | 11735 |
| DUSP1 | 11733 |
| GNG4 | 11731 |
| PSMC1 | 11724 |
| CTNNA1 | 11711 |
| RAF1 | 11708 |
| CASP10 | 11704 |
| NR5A2 | 11680 |
| HRAS | 11673 |
| SMAD9 | 11670 |
| SLC38A9 | 11664 |
| MAPK12 | 11663 |
| PSMD3 | 11655 |
| AGO2 | 11647 |
| DEPDC1B | 11636 |
| ARHGAP44 | 11618 |
| RGS14 | 11616 |
| FAM13B | 11613 |
| PRKCE | 11606 |
| MADD | 11599 |
| GRB10 | 11598 |
| ZDHHC9 | 11585 |
| SH3PXD2A | 11583 |
| PIP4K2A | 11582 |
| ARHGAP11B | 11580 |
| THEM4 | 11571 |
| DKK4 | 11570 |
| ANKFY1 | 11567 |
| CDC42EP2 | 11566 |
| NUP107 | 11561 |
| PSME2 | 11555 |
| SHC2 | 11550 |
| RHOB | 11537 |
| POLR2L | 11530 |
| AATF | 11526 |
| MTR | 11525 |
| SOCS6 | 11523 |
| USP13 | 11521 |
| DYNLL2 | 11507 |
| IRS2 | 11497 |
| CIT | 11482 |
| MED1 | 11468 |
| NCF2 | 11446 |
| FLT3LG | 11436 |
| BRK1 | 11428 |
| USP2 | 11427 |
| TNFAIP1 | 11426 |
| KIF5B | 11419 |
| TMEM87A | 11413 |
| THBS1 | 11408 |
| NISCH | 11403 |
| SOS2 | 11402 |
| ZWINT | 11400 |
| TRIM33 | 11397 |
| SP1 | 11396 |
| PLIN3 | 11389 |
| KIF2C | 11386 |
| ARF6 | 11385 |
| RHOBTB1 | 11372 |
| PSMD14 | 11371 |
| CBY1 | 11354 |
| CENPI | 11351 |
| POLR2K | 11350 |
| EGFR | 11344 |
| ARL13B | 11337 |
| HDAC6 | 11333 |
| ARHGDIA | 11324 |
| GRIN2D | 11311 |
| MYD88 | 11305 |
| STRN | 11300 |
| PAK4 | 11295 |
| CDC42BPB | 11293 |
| ATP6V1G1 | 11283 |
| PSMD1 | 11280 |
| CSNK1A1 | 11277 |
| PARD6A | 11269 |
| TRIO | 11264 |
| ST3GAL3 | 11257 |
| FOXA1 | 11252 |
| PTPN12 | 11236 |
| IQGAP2 | 11231 |
| CENPQ | 11227 |
| LAMA3 | 11218 |
| SERPINE1 | 11217 |
| NRP2 | 11212 |
| CHN2 | 11204 |
| PDE3B | 11196 |
| STX5 | 11191 |
| RIT1 | 11188 |
| ACTR3 | 11186 |
| RHOA | 11182 |
| LAMTOR5 | 11181 |
| FARP1 | 11169 |
| POLR2F | 11158 |
| DUSP10 | 11134 |
| TF | 11111 |
| ARHGEF11 | 11110 |
| CASP3 | 11107 |
| SMURF2 | 11093 |
| FSTL3 | 11092 |
| RNF20 | 11085 |
| CASP9 | 11084 |
| ARAF | 11076 |
| SH2D2A | 11047 |
| GMIP | 11044 |
| SYDE1 | 11040 |
| NUMB | 11036 |
| RBMX | 11027 |
| PIK3C3 | 11026 |
| PSAP | 11023 |
| YY1 | 11015 |
| UCN | 11013 |
| MAGED1 | 11010 |
| RACGAP1 | 10990 |
| RAP1GDS1 | 10985 |
| FKBP1A | 10960 |
| CDC37 | 10941 |
| PSPN | 10939 |
| FOS | 10931 |
| PPP2CA | 10917 |
| COPS2 | 10902 |
| PPP1CA | 10883 |
| WWP2 | 10881 |
| KDM4C | 10878 |
| SLK | 10872 |
| ARL2 | 10857 |
| DGKA | 10844 |
| PPP2R5B | 10834 |
| INTU | 10822 |
| SAMM50 | 10805 |
| MXD4 | 10802 |
| ADD3 | 10801 |
| ATP6V0E2 | 10798 |
| PTENP1 | 10778 |
| GSK3B | 10767 |
| DBN1 | 10764 |
| INSR | 10761 |
| DLGAP5 | 10758 |
| CENPC | 10756 |
| CDC20 | 10732 |
| AAMP | 10725 |
| PDGFC | 10716 |
| UBA52 | 10707 |
| MAPK1 | 10705 |
| CDK4 | 10698 |
| EVC | 10692 |
| PLEKHG2 | 10691 |
| ACTB | 10683 |
| CNOT6L | 10678 |
| CSNK2A1 | 10637 |
| PHLPP1 | 10618 |
| ZAP70 | 10613 |
| TSC1 | 10605 |
| TNFRSF10D | 10566 |
| ADRA1D | 10553 |
| TLE3 | 10548 |
| CENPE | 10538 |
| ERBB2 | 10533 |
| PDHX | 10522 |
| CTBP2 | 10508 |
| RRAS2 | 10503 |
| ETV4 | 10479 |
| FES | 10476 |
| JAK1 | 10468 |
| PAK2 | 10458 |
| CAB39 | 10457 |
| ARHGAP23 | 10454 |
| ALDH1A1 | 10453 |
| NOXA1 | 10451 |
| ATP6V1C1 | 10444 |
| ECT2 | 10441 |
| IL6R | 10440 |
| DZIP1 | 10439 |
| MYH14 | 10431 |
| PSMB9 | 10430 |
| PSEN1 | 10427 |
| FZD7 | 10425 |
| FAM135A | 10410 |
| ATF1 | 10407 |
| FRAT2 | 10404 |
| PHB | 10399 |
| NCKIPSD | 10395 |
| SRY | 10390 |
| EPAS1 | 10387 |
| OXER1 | 10369 |
| NOS3 | 10359 |
| SPTBN1 | 10356 |
| YKT6 | 10349 |
| VAPA | 10346 |
| GTF2A2 | 10341 |
| RGS3 | 10335 |
| PSMB6 | 10326 |
| IFT88 | 10317 |
| PLTP | 10314 |
| PSMC6 | 10307 |
| PDE8A | 10306 |
| TNFSF10 | 10292 |
| SNX3 | 10279 |
| IL32 | 10276 |
| FOXO1 | 10275 |
| WNT7B | 10260 |
| AREG | 10258 |
| VPS26A | 10251 |
| TRIM27 | 10241 |
| CHD4 | 10236 |
| TRIB1 | 10234 |
| CEP97 | 10215 |
| RRAGB | 10211 |
| ARFGAP3 | 10209 |
| PSMC4 | 10196 |
| ARHGEF10L | 10192 |
| CDC42SE2 | 10187 |
| TNRC6C | 10180 |
| TJP1 | 10173 |
| KAT2B | 10158 |
| TNKS | 10153 |
| IL1RAP | 10146 |
| H2AFX | 10131 |
| CLIP3 | 10109 |
| PIK3CD | 10102 |
| FKBP5 | 10097 |
| IGF2BP1 | 10096 |
| SH2B3 | 10091 |
| ADORA2A | 10081 |
| BRAF | 10077 |
| PCSK6 | 10075 |
| DSP | 10069 |
| PPP2R1A | 10064 |
| HMOX2 | 10061 |
| RUVBL1 | 10058 |
| RDH5 | 10055 |
| PKN1 | 10044 |
| ACBD5 | 10037 |
| MYH9 | 10036 |
| PTEN | 10023 |
| MST1 | 10022 |
| INCENP | 10005 |
| GPR176 | 10004 |
| STAT5A | 10000 |
| APOC2 | 9992 |
| SGO2 | 9987 |
| DGKK | 9983 |
| CCNT1 | 9958 |
| CCDC88A | 9957 |
| CENPM | 9951 |
| CDC73 | 9943 |
| MMP2 | 9932 |
| SNAI1 | 9927 |
| ZNF512B | 9920 |
| UACA | 9918 |
| POLR2E | 9916 |
| NCOA1 | 9914 |
| KIF18A | 9884 |
| KDM1B | 9876 |
| KIF14 | 9870 |
| ACKR2 | 9863 |
| RTN4 | 9862 |
| VAV3 | 9861 |
| FAF2 | 9859 |
| PSMD9 | 9853 |
| FRAT1 | 9849 |
| PRKAA1 | 9840 |
| LRP6 | 9800 |
| EEPD1 | 9795 |
| GNAI3 | 9793 |
| AP2M1 | 9787 |
| BIRC5 | 9771 |
| DLG3 | 9763 |
| MST1R | 9745 |
| CHD8 | 9744 |
| RBBP7 | 9712 |
| KPNA2 | 9708 |
| ALDH3A2 | 9706 |
| ADORA2B | 9698 |
| B9D2 | 9695 |
| SPPL2A | 9693 |
| MRAS | 9679 |
| PSMD5 | 9676 |
| STAM | 9665 |
| DLG4 | 9664 |
| ARHGEF9 | 9653 |
| CSNK2A2 | 9641 |
| ROR1 | 9638 |
| MBD3 | 9635 |
| PEAK1 | 9614 |
| GPS2 | 9607 |
| PPP2CB | 9606 |
| KAT2A | 9597 |
| GNB2 | 9583 |
| TYK2 | 9579 |
| TGFA | 9574 |
| SOCS1 | 9561 |
| PLK1 | 9548 |
| TAS2R4 | 9532 |
| DIAPH3 | 9508 |
| ARAP3 | 9501 |
| ABI1 | 9492 |
| ARHGAP5 | 9487 |
| ARHGAP8 | 9485 |
| AMER1 | 9484 |
| SEH1L | 9474 |
| TLE2 | 9473 |
| DAAM1 | 9439 |
| ANLN | 9438 |
| SMAD1 | 9435 |
| VEGFA | 9433 |
| USP34 | 9391 |
| TIAL1 | 9377 |
| ARPC1B | 9372 |
| PSMD7 | 9371 |
| HSP90AB1 | 9363 |
| ATP6V1H | 9358 |
| PSMD10 | 9356 |
| ARHGAP21 | 9336 |
| NCOR2 | 9331 |
| WNT2B | 9328 |
| HBEGF | 9320 |
| ARHGEF26 | 9307 |
| TNFRSF10A | 9306 |
| SCAI | 9277 |
| MAPK7 | 9270 |
| PIK3R1 | 9259 |
| NCOR1 | 9256 |
| PSMB7 | 9253 |
| DUSP8 | 9251 |
| MCHR1 | 9250 |
| AHCYL1 | 9245 |
| CBX8 | 9242 |
| MIB2 | 9222 |
| EIF4EBP1 | 9212 |
| TFDP2 | 9210 |
| PTK2 | 9198 |
| USP15 | 9193 |
| FZD5 | 9179 |
| KANK1 | 9175 |
| UBE2M | 9174 |
| ITPR1 | 9146 |
| SKA1 | 9144 |
| USP9X | 9136 |
| ADCY1 | 9122 |
| ITGAV | 9120 |
| TNFRSF1A | 9118 |
| PLAT | 9105 |
| RBPJ | 9099 |
| NCOA2 | 9072 |
| RACK1 | 9064 |
| PRMT1 | 9055 |
| PHC1 | 9053 |
| PLPPR1 | 9043 |
| CDK8 | 9040 |
| MAP3K11 | 9031 |
| BAX | 9026 |
| POTEE | 9019 |
| UBB | 9013 |
| IHH | 8989 |
| ATN1 | 8980 |
| CLASP2 | 8977 |
| ASH2L | 8974 |
| PDE11A | 8972 |
| TMED5 | 8971 |
| RGS12 | 8968 |
| CENPT | 8952 |
| DSG2 | 8936 |
| CYP26B1 | 8914 |
| TPH1 | 8911 |
| AXIN1 | 8908 |
| TNRC6B | 8904 |
| PSMA4 | 8902 |
| HGS | 8898 |
| IQCE | 8895 |
| ARHGAP33 | 8894 |
| SH3GL1 | 8879 |
| NR1H3 | 8878 |
| STAP2 | 8852 |
| RBL1 | 8842 |
| BMI1 | 8838 |
| PPP3R1 | 8832 |
| ARHGEF39 | 8819 |
| ARHGAP27 | 8813 |
| SFN | 8812 |
| TWF1 | 8810 |
| HIF1A | 8807 |
| P2RY2 | 8802 |
| MCAM | 8792 |
| VANGL1 | 8782 |
| KCTD3 | 8775 |
| RALGDS | 8765 |
| MDK | 8761 |
| ITGB1 | 8760 |
| PPP2R1B | 8759 |
| KLC1 | 8755 |
| DRD5 | 8753 |
| STRAP | 8749 |
| CUL1 | 8725 |
| PDK4 | 8724 |
| UHRF1BP1L | 8723 |
| GAB2 | 8722 |
| PPP1R12B | 8721 |
| POLR2I | 8717 |
| FZD1 | 8714 |
| MAP2K1 | 8704 |
| PPID | 8703 |
| RHOU | 8693 |
| CSK | 8692 |
| ELF3 | 8687 |
| GATAD2A | 8682 |
| PSMD4 | 8670 |
| CAMK2A | 8669 |
| FMNL2 | 8666 |
| JUND | 8660 |
| TERT | 8656 |
| GTF2F2 | 8650 |
| PSMC5 | 8646 |
| SMAD2 | 8639 |
| ATP6V1B1 | 8635 |
| WDR81 | 8629 |
| CENPA | 8625 |
| TXNL1 | 8617 |
| RXRA | 8607 |
| ARHGAP29 | 8603 |
| AHCTF1 | 8598 |
| CBX4 | 8580 |
| PPP3CB | 8574 |
| NOX3 | 8566 |
| ZW10 | 8564 |
| MAPKAPK5 | 8556 |
| ECE2 | 8542 |
| IL17RD | 8541 |
| HDAC5 | 8527 |
| DOCK5 | 8523 |
| PTAFR | 8514 |
| ID1 | 8511 |
| TTC21B | 8500 |
| DAGLB | 8497 |
| FGF17 | 8493 |
| ATP2A1 | 8492 |
| CRABP2 | 8479 |
| GRB7 | 8477 |
| NR3C1 | 8476 |
| TIAM1 | 8451 |
| UBE2D3 | 8449 |
| MARK3 | 8448 |
| THBS3 | 8446 |
| SPINT1 | 8433 |
| PTPRU | 8430 |
| FER | 8408 |
| IFT140 | 8404 |
| EGR3 | 8399 |
| GDNF | 8396 |
| GNG7 | 8395 |
| TRIP10 | 8370 |
| CSNK2B | 8368 |
| ZDHHC21 | 8365 |
| DKK1 | 8362 |
| VCL | 8357 |
| GIT2 | 8347 |
| ACVR1B | 8345 |
| GFRA3 | 8334 |
| GNAL | 8331 |
| CKAP4 | 8327 |
| ARHGEF16 | 8317 |
| PHLPP2 | 8313 |
| CHEK1 | 8292 |
| WDR91 | 8290 |
| TNFAIP3 | 8284 |
| CENPU | 8282 |
| NOTCH1 | 8281 |
| BAIAP2L2 | 8278 |
| NCK2 | 8271 |
| MAD1L1 | 8264 |
| SPRED3 | 8248 |
| ULK3 | 8247 |
| GNAI2 | 8246 |
| RPS6KB2 | 8241 |
| DYNC1LI2 | 8235 |
| TNS3 | 8224 |
| CREBBP | 8214 |
| TAB2 | 8201 |
| DUSP7 | 8185 |
| AGO1 | 8173 |
| DLG1 | 8171 |
| HEY1 | 8169 |
| PGRMC2 | 8168 |
| PSMD12 | 8163 |
| RPS6KA1 | 8159 |
| NOTCH3 | 8138 |
| NPFFR1 | 8135 |
| ADCY9 | 8130 |
| BCL2L11 | 8099 |
| GFOD1 | 8080 |
| STAT3 | 8078 |
| ERBB3 | 8072 |
| ARHGEF5 | 8063 |
| PSME3 | 8052 |
| MFN1 | 8050 |
| STK38 | 8049 |
| PTPN2 | 8048 |
| KLB | 8045 |
| FAM91A1 | 8041 |
| MAPRE1 | 8020 |
| KDM1A | 8018 |
| FRS2 | 8007 |
| CASP2 | 7990 |
| GGA3 | 7982 |
| CENPF | 7980 |
| SHC3 | 7979 |
| CAMK4 | 7978 |
| ATP6V1A | 7965 |
| NUP85 | 7946 |
| PLCG2 | 7942 |
| NUP98 | 7940 |
| RHEB | 7936 |
| ZFYVE16 | 7925 |
| DLD | 7922 |
| NDUFA5 | 7919 |
| FGFRL1 | 7915 |
| POFUT1 | 7899 |
| GPNMB | 7893 |
| SOX4 | 7867 |
| TNS4 | 7866 |
| GNAZ | 7864 |
| RBX1 | 7850 |
| GPHA2 | 7837 |
| GNG5 | 7830 |
| CCNT2 | 7818 |
| POLR2B | 7815 |
| FERMT2 | 7814 |
| LAT | 7813 |
| CDK2 | 7809 |
| UHMK1 | 7794 |
| RHOT1 | 7793 |
| GSK3A | 7787 |
| MTOR | 7785 |
| PARD6B | 7771 |
| CCL16 | 7766 |
| APOE | 7759 |
| GALR2 | 7752 |
| SKIL | 7744 |
| DOK1 | 7718 |
| TGFBR2 | 7714 |
| HHAT | 7712 |
| WDR83 | 7711 |
| RING1 | 7710 |
| PCP2 | 7703 |
| DEF6 | 7696 |
| PPP1CB | 7685 |
| PLD2 | 7673 |
| ARHGEF3 | 7669 |
| RPS6KB1 | 7667 |
| ARHGEF25 | 7665 |
| SH2B1 | 7640 |
| DYNC1H1 | 7639 |
| FABP5 | 7635 |
| BAG4 | 7633 |
| GOLGA8R | 7631 |
| CPNE8 | 7624 |
| ROCK1 | 7591 |
| POLR2H | 7590 |
| RDH14 | 7587 |
| EPOR | 7581 |
| TRRAP | 7571 |
| CDKN1A | 7569 |
| FLRT2 | 7566 |
| UCN2 | 7561 |
| STIP1 | 7550 |
| GPSM2 | 7530 |
| TBP | 7524 |
| PYGO1 | 7518 |
| SREBF1 | 7517 |
| SRC | 7516 |
| JUNB | 7447 |
| YWHAH | 7417 |
| NFKB1 | 7409 |
| GPS1 | 7406 |
| EMD | 7404 |
| KLC4 | 7401 |
| AP2A2 | 7391 |
| TRADD | 7383 |
| SPTBN2 | 7379 |
| RCOR1 | 7376 |
| NRTN | 7357 |
| GRAP | 7339 |
| CPT1B | 7323 |
| F2R | 7320 |
| PRKAG1 | 7302 |
| HDAC8 | 7301 |
| CAMKK2 | 7294 |
| CTNNBIP1 | 7284 |
| DOCK7 | 7277 |
| ARPC3 | 7237 |
| LMAN1 | 7220 |
| POLR2C | 7212 |
| GOLGA7 | 7208 |
| GRK3 | 7203 |
| LAMB1 | 7198 |
| NEURL1B | 7190 |
| PLIN1 | 7186 |
| MAP3K7 | 7172 |
| PAQR3 | 7167 |
| KHDRBS3 | 7153 |
| MYLK | 7150 |
| PPP1CC | 7149 |
| ARHGAP11A | 7148 |
| DTX2 | 7114 |
| DUSP6 | 7113 |
| KLC2 | 7112 |
| PTGES3 | 7103 |
| WASF2 | 7096 |
| EFHD2 | 7090 |
| VANGL2 | 7088 |
| CHUK | 7086 |
| STBD1 | 7077 |
| PHC2 | 7072 |
| HSPB1 | 7039 |
| STAG1 | 7037 |
| NR4A1 | 7026 |
| FARP2 | 7020 |
| TAOK3 | 6995 |
| CHD1 | 6976 |
| MEF2A | 6959 |
| CNKSR1 | 6956 |
| SHH | 6953 |
| TRAK1 | 6949 |
| WNT11 | 6940 |
| RBBP4 | 6938 |
| CXCL8 | 6916 |
| PTPN1 | 6909 |
| IFT172 | 6880 |
| SPOP | 6873 |
| OBSCN | 6868 |
| TIAM2 | 6863 |
| GNRHR2 | 6834 |
| RAP1B | 6830 |
| ST3GAL6 | 6829 |
| ARRB2 | 6824 |
| LATS1 | 6798 |
| GNB1 | 6796 |
| GIPR | 6793 |
| VAPB | 6785 |
| PIP5K1C | 6778 |
| GALNT3 | 6774 |
| SMARCA4 | 6773 |
| KTN1 | 6769 |
| DOCK1 | 6760 |
| CDC14B | 6755 |
| TNKS2 | 6742 |
| SAV1 | 6741 |
| UBE2D1 | 6734 |
| CARM1 | 6725 |
| EGR2 | 6724 |
| NSL1 | 6722 |
| FLRT1 | 6694 |
| IRS1 | 6691 |
| TAS1R3 | 6672 |
| C5AR2 | 6671 |
| XCL1 | 6670 |
| LBR | 6666 |
| EPS15L1 | 6655 |
| BIRC3 | 6654 |
| PPARG | 6636 |
| EREG | 6635 |
| TCF12 | 6626 |
| STK4 | 6620 |
| RANGAP1 | 6615 |
| E2F4 | 6609 |
| PCSK5 | 6597 |
| STK11 | 6595 |
| WDR11 | 6588 |
| SPHK1 | 6587 |
| DBT | 6586 |
| SEM1 | 6566 |
| BUB1 | 6536 |
| TCF7L1 | 6533 |
| FN1 | 6525 |
| NLN | 6521 |
| GNRH1 | 6508 |
| LYPLA1 | 6485 |
| GTF2F1 | 6481 |
| STUB1 | 6475 |
| SWAP70 | 6466 |
| PKN3 | 6455 |
| SRF | 6447 |
| LEO1 | 6444 |
| ANOS1 | 6441 |
| DLK1 | 6437 |
| PSMA3 | 6422 |
| ESR2 | 6378 |
| PEA15 | 6376 |
| STRADB | 6364 |
| CUL3 | 6363 |
| PTK6 | 6358 |
| PRKAA2 | 6357 |
| KIF3A | 6347 |
| GRB2 | 6346 |
| PDE4A | 6332 |
| LYN | 6328 |
| RPS6KA3 | 6316 |
| KCTD13 | 6315 |
| ARHGAP17 | 6310 |
| ABL2 | 6296 |
| RGL2 | 6290 |
| CTNNB1 | 6288 |
| CKB | 6276 |
| VPS35 | 6275 |
| KISS1 | 6261 |
| HCAR3 | 6248 |
| CSNK1E | 6238 |
| ARHGAP26 | 6232 |
| PLEKHG4 | 6215 |
| COL6A2 | 6195 |
| SHKBP1 | 6194 |
| NPW | 6185 |
| WIPF2 | 6174 |
| AKT1 | 6160 |
| DHRS3 | 6151 |
| RAB4B | 6116 |
| JUN | 6103 |
| IKBKB | 6100 |
| XIAP | 6096 |
| PSMD8 | 6091 |
| CASP8 | 6085 |
| TACC3 | 6081 |
| AP2S1 | 6073 |
| ARHGEF7 | 6055 |
| ARMCX3 | 6051 |
| LIN7B | 6030 |
| SHARPIN | 6027 |
| PELP1 | 6020 |
| RBCK1 | 6012 |
| SMAD7 | 6006 |
| RIPK1 | 6000 |
| HNRNPH1 | 5994 |
| KLC3 | 5986 |
| SLC4A7 | 5963 |
| AKAP12 | 5962 |
| TAOK1 | 5951 |
| RPS6KA5 | 5949 |
| SPRED2 | 5946 |
| STAM2 | 5933 |
| PIN1 | 5922 |
| DTX4 | 5869 |
| USP8 | 5864 |
| ADCY6 | 5862 |
| PIK3CA | 5849 |
| TLE1 | 5826 |
| ARPC1A | 5822 |
| FGFR4 | 5810 |
| MOB1B | 5806 |
| NCKAP1 | 5794 |
| DYNC1I2 | 5783 |
| ELMO1 | 5782 |
| RPS27A | 5776 |
| ROCK2 | 5775 |
| RHOG | 5747 |
| ICMT | 5741 |
| IGF1R | 5730 |
| TMOD3 | 5728 |
| PARP1 | 5715 |
| DRAP1 | 5707 |
| AAAS | 5701 |
| ABCG8 | 5687 |
| JAK2 | 5664 |
| PSMA5 | 5657 |
| SPPL2B | 5650 |
| PPP3CC | 5641 |
| UTS2B | 5630 |
| GPR35 | 5616 |
| CBX6 | 5608 |
| RPS6 | 5569 |
| CCND3 | 5565 |
| HDAC1 | 5563 |
| HCAR2 | 5556 |
| ADAM10 | 5549 |
| WNT3 | 5541 |
| PDGFA | 5524 |
| RGS9 | 5517 |
| IFT52 | 5515 |
| SSTR2 | 5508 |
| GABRG2 | 5492 |
| SCRIB | 5488 |
| CETP | 5470 |
| RELA | 5468 |
| LAMTOR3 | 5467 |
| ARHGAP1 | 5462 |
| GPR143 | 5460 |
| TGFBR1 | 5447 |
| STAG2 | 5443 |
| VAV2 | 5425 |
| GALR1 | 5422 |
| AXL | 5419 |
| CTSD | 5416 |
| NUP43 | 5410 |
| USP21 | 5405 |
| RHOF | 5403 |
| MTX1 | 5395 |
| PIK3CB | 5379 |
| ARC | 5378 |
| TFDP1 | 5361 |
| KISS1R | 5359 |
| PSMD13 | 5353 |
| PAG1 | 5350 |
| SPRED1 | 5348 |
| FBXW7 | 5325 |
| CCNE1 | 5315 |
| PSEN2 | 5310 |
| DGKD | 5302 |
| FNTB | 5296 |
| PPP2R5C | 5293 |
| SMAD4 | 5290 |
| ADM | 5276 |
| NBEA | 5256 |
| RYK | 5246 |
| FGD1 | 5245 |
| RHOJ | 5241 |
| DYNC1LI1 | 5237 |
| POLR2A | 5219 |
| MYL9 | 5218 |
| LPAR2 | 5209 |
| SIRT6 | 5203 |
| TRAF1 | 5192 |
| BCR | 5190 |
| F2RL3 | 5187 |
| PPP5C | 5186 |
| STMN1 | 5180 |
| OTULIN | 5175 |
| GNAI1 | 5167 |
| CDON | 5163 |
| MYO6 | 5156 |
| TAX1BP3 | 5154 |
| CCNC | 5121 |
| SMO | 5118 |
| PIP4K2B | 5102 |
| TSC2 | 5097 |
| CDK9 | 5091 |
| ALDH1A2 | 5079 |
| WASF3 | 5070 |
| TFF1 | 5067 |
| MAP2K5 | 5053 |
| PMF1 | 5043 |
| RRAGA | 5038 |
| MSI2 | 5020 |
| PLCB3 | 4999 |
| FMNL1 | 4980 |
| SUFU | 4979 |
| TAB3 | 4960 |
| FST | 4958 |
| RASA1 | 4950 |
| PSMC2 | 4948 |
| MYH10 | 4942 |
| GFAP | 4934 |
| PXN | 4926 |
| SMC3 | 4924 |
| TLR9 | 4913 |
| PHIP | 4905 |
| ESRP2 | 4883 |
| PSME1 | 4861 |
| THBS2 | 4856 |
| PLCG1 | 4855 |
| DYNLL1 | 4853 |
| OTUD3 | 4849 |
| MKNK1 | 4846 |
| PSENEN | 4828 |
| NCOA3 | 4825 |
| INHBB | 4815 |
| CYSLTR1 | 4813 |
| LRP5 | 4812 |
| ERBIN | 4809 |
| DIAPH2 | 4808 |
| MPP7 | 4807 |
| ALDH8A1 | 4804 |
| SYNGAP1 | 4797 |
| NELFB | 4775 |
| EIF4E | 4766 |
| TAS1R1 | 4764 |
| EVL | 4757 |
| ABCA1 | 4752 |
| PIK3R3 | 4734 |
| RNF2 | 4732 |
| RNF111 | 4714 |
| PDE4C | 4711 |
| PRKCA | 4709 |
| DVL1 | 4696 |
| CFLAR | 4684 |
| POLR2D | 4674 |
| WNT6 | 4663 |
| CPSF7 | 4652 |
| PDK1 | 4644 |
| OSBPL11 | 4618 |
| PDK3 | 4617 |
| SPTAN1 | 4610 |
| IRAK1 | 4593 |
| IFT122 | 4583 |
| EED | 4581 |
| ARPC2 | 4575 |
| FAM169A | 4565 |
| HCAR1 | 4549 |
| USF1 | 4545 |
| ALS2 | 4492 |
| CDC42 | 4489 |
| ARHGAP9 | 4486 |
| JUP | 4478 |
| CCDC88C | 4477 |
| NRAS | 4465 |
| NCBP1 | 4458 |
| RAB4A | 4453 |
| FAS | 4451 |
| FOXO3 | 4415 |
| MAPK14 | 4391 |
| PPP2R5D | 4385 |
| GPSM3 | 4383 |
| CENPN | 4377 |
| FZD8 | 4376 |
| OXTR | 4374 |
| AGTR1 | 4371 |
| ITPR2 | 4366 |
| ABHD17B | 4341 |
| PRR5 | 4323 |
| SSTR5 | 4318 |
| ID3 | 4312 |
| CYBA | 4283 |
| FOXO4 | 4276 |
| RICTOR | 4274 |
| YAP1 | 4225 |
| FLT4 | 4214 |
| KRAS | 4210 |
| ARHGEF19 | 4198 |
| WDR35 | 4193 |
| CAMK2G | 4176 |
| BMPR2 | 4145 |
| TP53 | 4144 |
| DLG2 | 4143 |
| FRS3 | 4125 |
| SYDE2 | 4108 |
| DDX39B | 4095 |
| FGF23 | 4091 |
| SPRY2 | 4083 |
| FAM13A | 4071 |
| COL6A3 | 4068 |
| DGKQ | 4067 |
| DOCK8 | 4066 |
| YWHAB | 4062 |
| EPO | 4044 |
| CASR | 4021 |
| DST | 4001 |
| AKT2 | 3993 |
| TGIF1 | 3964 |
| AP2B1 | 3955 |
| ABL1 | 3944 |
| PICALM | 3941 |
| SPRY1 | 3939 |
| RASAL2 | 3937 |
| PSMB3 | 3928 |
| SGO1 | 3925 |
| OTUD7B | 3920 |
| POLR2G | 3910 |
| AP2A1 | 3903 |
| LRRC41 | 3889 |
| RGS10 | 3858 |
| MAPK13 | 3846 |
| IL6ST | 3837 |
| GAS8 | 3836 |
| XPO1 | 3824 |
| RHPN2 | 3804 |
| CYFIP1 | 3785 |
| FYN | 3783 |
| GNB4 | 3781 |
| VWF | 3777 |
| BCL2 | 3762 |
| PIP5K1A | 3743 |
| CCR10 | 3730 |
| RASGRF1 | 3721 |
| APC | 3716 |
| CCR4 | 3715 |
| MYC | 3708 |
| FADD | 3704 |
| FASN | 3698 |
| WDR19 | 3682 |
| PSMB2 | 3678 |
| MLST8 | 3677 |
| PKP4 | 3674 |
| SRGAP1 | 3662 |
| HNRNPA1 | 3661 |
| NSFL1C | 3630 |
| SRGAP2 | 3627 |
| SKI | 3621 |
| LAMTOR4 | 3602 |
| PRKAB2 | 3594 |
| TNRC6A | 3580 |
| DUSP16 | 3571 |
| HNRNPC | 3563 |
| NDE1 | 3555 |
| MTA1 | 3553 |
| PDHB | 3550 |
| HECW1 | 3499 |
| PTCH1 | 3498 |
| HTR1D | 3482 |
| CHN1 | 3467 |
| DOCK9 | 3436 |
| MMP3 | 3425 |
| NTSR1 | 3412 |
| PRKACA | 3407 |
| ITGA3 | 3390 |
| CAMK2D | 3358 |
| ARAP2 | 3353 |
| CDKN2B | 3352 |
| ARAP1 | 3351 |
| NPHP4 | 3341 |
| DGKG | 3322 |
| TBL1X | 3308 |
| RGS2 | 3297 |
| LGR5 | 3252 |
| MIB1 | 3250 |
| NF1 | 3245 |
| F3 | 3237 |
| GOPC | 3212 |
| DLAT | 3193 |
| PYGO2 | 3187 |
| PRKCH | 3185 |
| RDH16 | 3180 |
| SPARC | 3167 |
| TRAF6 | 3150 |
| IRAK4 | 3137 |
| STAT6 | 3128 |
| EBAG9 | 3126 |
| NPB | 3121 |
| KAT5 | 3115 |
| GAB1 | 3105 |
| MUC13 | 3097 |
| STOM | 3093 |
| LIMK1 | 3082 |
| DNMBP | 3080 |
| ARPC5 | 3073 |
| RFNG | 3072 |
| CLASP1 | 3071 |
| PSMC3 | 3070 |
| SMAD5 | 3047 |
| NCK1 | 3010 |
| HDAC4 | 2998 |
| WWOX | 2994 |
| EGR1 | 2989 |
| CCT7 | 2974 |
| DISP2 | 2959 |
| CXCR2 | 2899 |
| PRKACB | 2885 |
| USP4 | 2874 |
| SLITRK5 | 2858 |
| ACTR2 | 2855 |
| RAC3 | 2837 |
| RND1 | 2828 |
| HDAC10 | 2826 |
| ADAP1 | 2817 |
| ARHGAP12 | 2812 |
| ZFYVE9 | 2801 |
| TBL1XR1 | 2795 |
| LFNG | 2769 |
| BTRC | 2757 |
| PLEKHG6 | 2747 |
| PIK3R2 | 2728 |
| CENPP | 2725 |
| CDK5 | 2721 |
| NUP133 | 2708 |
| RANBP10 | 2698 |
| NRP1 | 2695 |
| GPR83 | 2691 |
| YES1 | 2690 |
| MOSPD2 | 2673 |
| KHDRBS1 | 2669 |
| CHD3 | 2661 |
| GRIN2B | 2648 |
| ARHGAP18 | 2628 |
| FLOT1 | 2624 |
| CGN | 2619 |
| LAMC1 | 2611 |
| ARHGAP22 | 2602 |
| RHOD | 2596 |
| PDE7A | 2591 |
| MEN1 | 2581 |
| RAB6A | 2578 |
| VRK3 | 2573 |
| RBFOX2 | 2561 |
| LAMA1 | 2553 |
| ARFGAP2 | 2547 |
| TRA2B | 2539 |
| ARHGDIG | 2530 |
| WDR6 | 2528 |
| POU2F1 | 2513 |
| CUL5 | 2485 |
| EPS15 | 2479 |
| PDHA1 | 2478 |
| FZD3 | 2458 |
| TULP3 | 2451 |
| ABI2 | 2431 |
| OPRD1 | 2430 |
| FGFR3 | 2426 |
| FNBP1L | 2414 |
| BRAP | 2384 |
| DOCK4 | 2380 |
| CAPZB | 2376 |
| GRK2 | 2372 |
| RNF43 | 2353 |
| RPS6KA2 | 2339 |
| PSMB4 | 2330 |
| CSNK1G2 | 2329 |
| GPR161 | 2317 |
| RGS19 | 2301 |
| LRRC1 | 2299 |
| LAMC3 | 2298 |
| BUB3 | 2290 |
| RCE1 | 2289 |
| GABRB3 | 2287 |
| FMNL3 | 2271 |
| GRK6 | 2263 |
| SH2B2 | 2259 |
| MYO9A | 2252 |
| TBXA2R | 2235 |
| GATAD2B | 2228 |
| CCNK | 2223 |
| PIK3R4 | 2219 |
| ARHGEF12 | 2216 |
| TRAK2 | 2191 |
| SOX13 | 2184 |
| PPP1R12A | 2182 |
| CDC42EP1 | 2171 |
| PLXNA1 | 2146 |
| PLXNB1 | 2132 |
| PRKAR1B | 2113 |
| E2F5 | 2102 |
| HSP90AA1 | 2096 |
| MUC20 | 2082 |
| YWHAG | 2081 |
| LTB4R2 | 2072 |
| ADGRE2 | 2068 |
| GNB3 | 2063 |
| PSMB1 | 2062 |
| PML | 2057 |
| PIP5K1B | 2051 |
| RALGAPA1 | 2044 |
| RALBP1 | 2026 |
| PAK1 | 2021 |
| MYH11 | 1998 |
| NCKAP1L | 1980 |
| HDAC11 | 1970 |
| GPR39 | 1956 |
| MDM2 | 1942 |
| CTTN | 1934 |
| ARHGEF4 | 1931 |
| SOS1 | 1928 |
| ARTN | 1918 |
| MYO19 | 1909 |
| PLEKHG1 | 1905 |
| TCF7L2 | 1893 |
| ABHD6 | 1891 |
| LEMD3 | 1868 |
| SH3KBP1 | 1864 |
| ELMO2 | 1854 |
| ARHGEF18 | 1850 |
| DVL2 | 1843 |
| ACVR2B | 1830 |
| ARHGAP4 | 1829 |
| PSMA7 | 1820 |
| SENP1 | 1811 |
| YWHAZ | 1810 |
| ATP6V1F | 1771 |
| PTPN11 | 1770 |
| PRKAR2A | 1753 |
| IFT57 | 1736 |
| NGFR | 1726 |
| RXRB | 1725 |
| SMPD3 | 1715 |
| SGK1 | 1698 |
| PRKCI | 1681 |
| TPM4 | 1674 |
| MATK | 1673 |
| HSPE1 | 1662 |
| PHC3 | 1660 |
| PBX1 | 1631 |
| TGIF2 | 1624 |
| RNF146 | 1622 |
| KREMEN2 | 1609 |
| RASA2 | 1608 |
| PTPRA | 1606 |
| WWC1 | 1596 |
| PPARD | 1594 |
| CDKN1B | 1590 |
| GNAQ | 1588 |
| DGKH | 1586 |
| TEX2 | 1573 |
| WWP1 | 1572 |
| LAMA4 | 1568 |
| SMC1A | 1560 |
| LAMTOR1 | 1557 |
| UBC | 1551 |
| ACVR2A | 1545 |
| NAB1 | 1529 |
| LTB4R | 1507 |
| SHOC2 | 1499 |
| CENPL | 1495 |
| ATP6V0D2 | 1494 |
| APOC1 | 1491 |
| PSMB5 | 1484 |
| EPN1 | 1478 |
| NLK | 1473 |
| MTMR1 | 1468 |
| CAB39L | 1458 |
| LYL1 | 1438 |
| MAPK8 | 1418 |
| VAMP3 | 1415 |
| ITGA2B | 1391 |
| GNB5 | 1388 |
| C1QBP | 1380 |
| PRKAB1 | 1376 |
| LAMB3 | 1365 |
| ATP6V1G2 | 1360 |
| ADCY2 | 1356 |
| CALM1 | 1340 |
| DOCK6 | 1298 |
| BAIAP2 | 1295 |
| SPINT2 | 1286 |
| PLEKHG5 | 1283 |
| F2 | 1246 |
| POLR2J | 1234 |
| REST | 1214 |
| PKN2 | 1213 |
| APH1A | 1209 |
| ARHGAP28 | 1191 |
| TRAF2 | 1180 |
| FRK | 1179 |
| RAD21 | 1178 |
| RASGRP3 | 1164 |
| CCL22 | 1142 |
| NCSTN | 1137 |
| PRKX | 1134 |
| NDUFS3 | 1132 |
| NEDD8 | 1131 |
| ITSN2 | 1120 |
| SKP1 | 1117 |
| STARD8 | 1115 |
| NRIP1 | 1114 |
| GPSM1 | 1094 |
| ATP6V1E2 | 1090 |
| CCDC115 | 1075 |
| YWHAQ | 1061 |
| JAG2 | 1048 |
| MCF2L | 1047 |
| CRKL | 1039 |
| RHOT2 | 1020 |
| BIRC2 | 1007 |
| SOX7 | 1003 |
| FGD2 | 990 |
| LAMB2 | 978 |
| VPS29 | 977 |
| SMAD6 | 964 |
| SCFD1 | 960 |
| PLEKHG3 | 958 |
| CD19 | 954 |
| CREB1 | 935 |
| GABRG3 | 919 |
| GRIN1 | 902 |
| GNAS | 900 |
| NSMAF | 884 |
| PSMD11 | 879 |
| E2F3 | 876 |
| UCHL5 | 875 |
| RAPGEF4 | 863 |
| ARHGAP40 | 861 |
| RDH13 | 839 |
| PSMB10 | 838 |
| KALRN | 828 |
| SMPD2 | 823 |
| ABCD3 | 821 |
| CENPO | 820 |
| RPTOR | 803 |
| LGR4 | 802 |
| PDPK1 | 782 |
| PTPRS | 779 |
| PPP3CA | 748 |
| PRKAG2 | 740 |
| SRRM1 | 723 |
| KREMEN1 | 715 |
| RUNX3 | 698 |
| HDAC2 | 693 |
| NUP160 | 683 |
| IL1RL1 | 665 |
| SUZ12 | 664 |
| FGF5 | 659 |
| MOB1A | 656 |
| ADGRE5 | 651 |
| STK10 | 642 |
| SOX6 | 637 |
| GTF2A1 | 633 |
| PORCN | 622 |
| RAP1A | 604 |
| RASGEF1A | 596 |
| DUSP9 | 580 |
| ID2 | 576 |
| RASA4 | 567 |
| WWTR1 | 555 |
| PPP2R5E | 554 |
| B4GALT1 | 540 |
| RALB | 524 |
| CCL28 | 520 |
| NMB | 517 |
| CAV2 | 495 |
| MAPK11 | 492 |
| ARHGAP10 | 474 |
| LAMC2 | 466 |
| RNF31 | 445 |
| SPOPL | 435 |
| ABR | 434 |
| STK3 | 428 |
| S1PR2 | 421 |
| CNR2 | 418 |
| NEDD4 | 383 |
| S1PR3 | 374 |
| NR1H2 | 373 |
| KCTD6 | 368 |
| PDE6A | 354 |
| TCIRG1 | 348 |
| BMPR1A | 345 |
| RARG | 335 |
| ARHGEF17 | 334 |
| CDK5R1 | 326 |
| RPS27 | 312 |
| ITSN1 | 311 |
| LAMTOR2 | 299 |
| CCND1 | 277 |
| PSMA6 | 261 |
| USP7 | 258 |
| HDAC7 | 254 |
| YWHAE | 253 |
| CDC14A | 249 |
| PAFAH1B1 | 237 |
| RBBP5 | 204 |
| SH3BP1 | 196 |
| LEPR | 183 |
| KITLG | 180 |
| PDE6G | 134 |
| KDM4B | 117 |
| RHOH | 103 |
| RAC1 | 95 |
| CSF2RA | 94 |
| ERCC6L | 86 |
| HDAC3 | 84 |
| OFD1 | 83 |
| CTBP1 | 73 |
| TPM3 | 71 |
| AKR1C3 | 54 |
| PLPPR2 | 52 |
| COPS4 | 51 |
| ARHGEF1 | 48 |
| NOXO1 | 21 |
| BAMBI | 13 |
| GRK5 | 12 |
| RANBP2 | 9 |
| PRKAR1A | 6 |
| KSR1 | 5 |
Metabolism
| 617 | |
|---|---|
| set | Metabolism |
| setSize | 1696 |
| pANOVA | 1.5e-07 |
| s.dist | 0.0783 |
| p.adjustANOVA | 2.29e-05 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SLC6A12 | 14525 |
| SEC24D | 14520 |
| MSMO1 | 14517 |
| SLC2A1 | 14515 |
| SLC3A2 | 14513 |
| AKR1B10 | 14512 |
| AKR1C2 | 14496 |
| CYP1A1 | 14494 |
| MTMR4 | 14488 |
| AKR1C1 | 14484 |
| HMGCS1 | 14473 |
| ADI1 | 14471 |
| SQLE | 14468 |
| ARG2 | 14464 |
| CEMIP | 14458 |
| UGT2B4 | 14457 |
| ACSS2 | 14455 |
| ENTPD7 | 14453 |
| IDI1 | 14452 |
| ACSM3 | 14445 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SLC6A12 | 14525 |
| SEC24D | 14520 |
| MSMO1 | 14517 |
| SLC2A1 | 14515 |
| SLC3A2 | 14513 |
| AKR1B10 | 14512 |
| AKR1C2 | 14496 |
| CYP1A1 | 14494 |
| MTMR4 | 14488 |
| AKR1C1 | 14484 |
| HMGCS1 | 14473 |
| ADI1 | 14471 |
| SQLE | 14468 |
| ARG2 | 14464 |
| CEMIP | 14458 |
| UGT2B4 | 14457 |
| ACSS2 | 14455 |
| ENTPD7 | 14453 |
| IDI1 | 14452 |
| ACSM3 | 14445 |
| GLRX | 14439 |
| APOC3 | 14431 |
| FADS1 | 14413 |
| HMGCR | 14408 |
| ACSF2 | 14400 |
| GSTA4 | 14391 |
| AOX1 | 14380 |
| AS3MT | 14376 |
| ARSG | 14366 |
| MVK | 14363 |
| SLC52A2 | 14355 |
| ACSL1 | 14340 |
| FUT3 | 14335 |
| UGDH | 14328 |
| DHCR7 | 14319 |
| RPL36AL | 14313 |
| ADH4 | 14312 |
| ACSL4 | 14281 |
| BPHL | 14275 |
| MT-CO3 | 14274 |
| PKLR | 14260 |
| RBP4 | 14250 |
| CMBL | 14247 |
| ARSB | 14246 |
| SREBF2 | 14223 |
| MVD | 14220 |
| AMPD2 | 14212 |
| CRYL1 | 14211 |
| PNPLA3 | 14198 |
| CYP4F2 | 14196 |
| CYP4F3 | 14195 |
| GCLC | 14194 |
| PLD1 | 14191 |
| FDFT1 | 14189 |
| PNPLA6 | 14177 |
| CHKA | 14176 |
| LSS | 14165 |
| GCKR | 14160 |
| PFKFB2 | 14153 |
| INPP1 | 14150 |
| ACBD4 | 14149 |
| TPH2 | 14138 |
| TKFC | 14126 |
| SLC26A1 | 14123 |
| ACAD10 | 14120 |
| CES3 | 14110 |
| SLC2A2 | 14109 |
| PLA2G2A | 14102 |
| ELOVL6 | 14093 |
| SEC24A | 14088 |
| SCLY | 14082 |
| ITPKA | 14078 |
| ACSS1 | 14077 |
| ABCB1 | 14065 |
| CA14 | 14063 |
| CTH | 14055 |
| GNS | 14052 |
| SULT1C4 | 14051 |
| SEC13 | 14049 |
| PNP | 14046 |
| TXNRD1 | 14041 |
| NDUFC2 | 14038 |
| SPTSSB | 14034 |
| ST3GAL4 | 14033 |
| ABCB4 | 14032 |
| TRIB3 | 14029 |
| PTDSS1 | 14025 |
| CYP3A7 | 14020 |
| SLC51B | 14011 |
| CYGB | 14010 |
| HMMR | 14001 |
| MT-CYB | 13980 |
| LHPP | 13964 |
| ESRRA | 13960 |
| NEU1 | 13953 |
| LPIN3 | 13949 |
| SDHB | 13948 |
| NCOA6 | 13941 |
| MMAB | 13940 |
| CSGALNACT2 | 13909 |
| LPIN2 | 13908 |
| PPARA | 13906 |
| FTCD | 13892 |
| GALK1 | 13889 |
| ESYT2 | 13884 |
| CHPF2 | 13877 |
| PYGB | 13867 |
| ASRGL1 | 13863 |
| OSBP | 13854 |
| PITPNB | 13834 |
| HSPG2 | 13832 |
| GBA | 13831 |
| GSTA1 | 13820 |
| OSBPL2 | 13812 |
| PSMF1 | 13810 |
| N6AMT1 | 13806 |
| SULT1E1 | 13803 |
| ACOT13 | 13798 |
| NME4 | 13796 |
| CYB5B | 13791 |
| ASAH1 | 13777 |
| NDUFAF2 | 13763 |
| SCO2 | 13759 |
| GDPD1 | 13747 |
| OAT | 13738 |
| PCCA | 13733 |
| COASY | 13714 |
| ABCC2 | 13713 |
| NUP37 | 13706 |
| GLUD1 | 13696 |
| AGT | 13674 |
| DHFR2 | 13673 |
| HK1 | 13660 |
| NEU3 | 13653 |
| ACSM5 | 13648 |
| COX20 | 13633 |
| CPT1A | 13626 |
| HMGCL | 13619 |
| COX10 | 13613 |
| WASL | 13611 |
| FADS2 | 13609 |
| HPRT1 | 13606 |
| ESYT1 | 13601 |
| LPCAT2 | 13599 |
| DNM2 | 13597 |
| MOCOS | 13596 |
| ACOT2 | 13592 |
| COQ10B | 13587 |
| FAAH2 | 13577 |
| AMACR | 13555 |
| GLO1 | 13553 |
| SLC23A1 | 13552 |
| EHHADH | 13541 |
| CES1 | 13506 |
| HAL | 13505 |
| RAN | 13497 |
| PPM1K | 13491 |
| AMT | 13487 |
| EP300 | 13485 |
| ALDOA | 13474 |
| DMGDH | 13469 |
| MAPKAPK2 | 13468 |
| HEXB | 13459 |
| KYAT1 | 13456 |
| PSME4 | 13450 |
| SEPHS2 | 13446 |
| APOA1 | 13433 |
| DHODH | 13429 |
| PARP9 | 13424 |
| PSMD2 | 13423 |
| ADRA2C | 13422 |
| SCD | 13413 |
| PHKG2 | 13392 |
| GPX2 | 13379 |
| GPAM | 13366 |
| CERS2 | 13365 |
| SLC9A1 | 13358 |
| ADH6 | 13353 |
| ACAT2 | 13351 |
| GUK1 | 13349 |
| ANGPTL4 | 13342 |
| NEU4 | 13335 |
| DHFR | 13334 |
| UGP2 | 13333 |
| PPOX | 13332 |
| ENPP3 | 13326 |
| KPNB1 | 13324 |
| UROC1 | 13310 |
| MID1IP1 | 13308 |
| POM121 | 13281 |
| HMGCS2 | 13280 |
| BCKDHA | 13255 |
| PIP4K2C | 13241 |
| SLCO2B1 | 13235 |
| GAPDH | 13233 |
| NAGS | 13232 |
| TAT | 13224 |
| GRHL1 | 13217 |
| CYP2W1 | 13216 |
| ARV1 | 13201 |
| B4GALNT1 | 13199 |
| MAT2A | 13193 |
| APOA2 | 13191 |
| SLC44A2 | 13182 |
| BDH2 | 13164 |
| NT5E | 13160 |
| CTSA | 13149 |
| ALDH3B1 | 13143 |
| TK1 | 13137 |
| GSTM2 | 13136 |
| SRR | 13135 |
| DECR1 | 13133 |
| SEPSECS | 13129 |
| B4GALT5 | 13121 |
| CHAC1 | 13119 |
| ACOT9 | 13115 |
| MRI1 | 13112 |
| OCRL | 13103 |
| PRODH2 | 13097 |
| XYLT2 | 13090 |
| PDK2 | 13086 |
| MIGA2 | 13080 |
| PCK2 | 13065 |
| ASL | 13064 |
| ABCD1 | 13062 |
| CHPF | 13050 |
| SEC24C | 13047 |
| AKR1B1 | 13033 |
| NUP210 | 13025 |
| ENPP2 | 13023 |
| AMDHD1 | 13018 |
| SULT2A1 | 13013 |
| SLC25A20 | 13011 |
| FDPS | 12999 |
| LMBRD1 | 12979 |
| GNG10 | 12977 |
| PLCB1 | 12974 |
| GPAT4 | 12941 |
| UPP1 | 12939 |
| PGAM1 | 12932 |
| NUDT3 | 12923 |
| PHYKPL | 12912 |
| GPAT3 | 12906 |
| CYP51A1 | 12901 |
| CDA | 12891 |
| CAD | 12876 |
| SHMT2 | 12864 |
| MT-ATP8 | 12839 |
| HSD17B11 | 12833 |
| SHMT1 | 12815 |
| GLCE | 12812 |
| PPP1R3C | 12799 |
| ACSL3 | 12797 |
| GBA2 | 12790 |
| TM7SF2 | 12785 |
| PDXK | 12784 |
| ITPR3 | 12768 |
| MOCS1 | 12763 |
| ABHD10 | 12754 |
| PITPNM1 | 12747 |
| COQ5 | 12720 |
| NDUFS6 | 12717 |
| DEGS1 | 12708 |
| HS3ST5 | 12706 |
| ANKRD1 | 12704 |
| GCAT | 12698 |
| POM121C | 12687 |
| AK2 | 12676 |
| NR1H4 | 12674 |
| DUT | 12668 |
| ISCA2 | 12647 |
| ARF1 | 12642 |
| ACSM2B | 12625 |
| INPP5K | 12614 |
| SULT1A1 | 12613 |
| STARD10 | 12612 |
| TYMP | 12610 |
| AASS | 12608 |
| PNPLA8 | 12549 |
| INPP5A | 12539 |
| MPC1 | 12529 |
| CSAD | 12525 |
| MBTPS1 | 12523 |
| SCP2 | 12518 |
| LPCAT4 | 12504 |
| PSMD6 | 12502 |
| ABCC1 | 12501 |
| PTGR2 | 12490 |
| SDHC | 12485 |
| L2HGDH | 12484 |
| GSTM4 | 12476 |
| ACAD8 | 12462 |
| DNPH1 | 12456 |
| PCK1 | 12455 |
| FUT1 | 12442 |
| DDO | 12429 |
| HK2 | 12426 |
| GNA11 | 12425 |
| ST3GAL1 | 12408 |
| INSIG2 | 12407 |
| PCYT1B | 12394 |
| UGT2B7 | 12393 |
| ACADM | 12392 |
| MT-CO1 | 12380 |
| SIN3A | 12373 |
| NDUFA9 | 12372 |
| RORA | 12360 |
| PPARGC1A | 12350 |
| PHYH | 12345 |
| MTHFD1L | 12340 |
| SERINC5 | 12338 |
| SLC19A2 | 12327 |
| PNPO | 12315 |
| CHST14 | 12314 |
| HYKK | 12313 |
| CYP19A1 | 12287 |
| AKR1B15 | 12286 |
| ECSIT | 12282 |
| DCTD | 12274 |
| MECR | 12270 |
| HACD2 | 12269 |
| MED29 | 12264 |
| HACD3 | 12248 |
| GLUL | 12218 |
| PSMA2 | 12203 |
| BRIP1 | 12189 |
| INPP5B | 12185 |
| NUDT19 | 12180 |
| GLS2 | 12173 |
| NDUFV3 | 12159 |
| RDH11 | 12131 |
| HIBADH | 12124 |
| GDPD3 | 12123 |
| LRPPRC | 12122 |
| DTYMK | 12116 |
| IMPA2 | 12106 |
| GALT | 12080 |
| BPNT1 | 12072 |
| APOM | 12064 |
| PSMA1 | 12052 |
| SLC22A3 | 12047 |
| ALAD | 12045 |
| ADCY7 | 12040 |
| CYP27B1 | 12039 |
| FIG4 | 12002 |
| KHK | 11987 |
| SLC5A6 | 11982 |
| GLYCTK | 11974 |
| CERS6 | 11969 |
| SPTLC3 | 11964 |
| HS6ST1 | 11962 |
| SCAP | 11960 |
| HSD17B12 | 11955 |
| CACNA1D | 11949 |
| ABCC3 | 11944 |
| NDUFB9 | 11939 |
| IQGAP1 | 11931 |
| THTPA | 11906 |
| VCAN | 11899 |
| LTA4H | 11893 |
| NSDHL | 11890 |
| CTPS2 | 11888 |
| MOGAT3 | 11883 |
| SLC25A1 | 11880 |
| ADH1A | 11878 |
| PECR | 11877 |
| GLA | 11875 |
| ACOT11 | 11870 |
| SMOX | 11863 |
| AK4 | 11832 |
| NUDT4 | 11830 |
| PFAS | 11829 |
| ACOX1 | 11824 |
| MGST2 | 11822 |
| ASNS | 11814 |
| UGT2A3 | 11797 |
| RGL1 | 11795 |
| PTGR1 | 11789 |
| MT-ATP6 | 11770 |
| ADO | 11757 |
| PSAT1 | 11756 |
| SUMF1 | 11754 |
| GNG4 | 11731 |
| MCCC1 | 11728 |
| PSMC1 | 11724 |
| FAAH | 11722 |
| SLC25A12 | 11721 |
| TALDO1 | 11703 |
| NAXE | 11697 |
| ISCU | 11683 |
| IDH3G | 11677 |
| MED22 | 11676 |
| AFMID | 11668 |
| PSMD3 | 11655 |
| CHST13 | 11654 |
| ARSI | 11653 |
| MCEE | 11652 |
| PLEKHA3 | 11648 |
| LPIN1 | 11643 |
| MAT1A | 11641 |
| EPHX2 | 11635 |
| SLC51A | 11608 |
| CBR1 | 11607 |
| ADSSL1 | 11605 |
| SLC7A5 | 11592 |
| PIP4K2A | 11582 |
| CA9 | 11579 |
| PLA2G6 | 11578 |
| GPD1 | 11575 |
| THEM4 | 11571 |
| NUP107 | 11561 |
| PSME2 | 11555 |
| ACP6 | 11552 |
| RUFY1 | 11544 |
| SEC24B | 11541 |
| ACACB | 11531 |
| CPS1 | 11529 |
| IDH1 | 11528 |
| MTR | 11525 |
| CHAC2 | 11498 |
| MED1 | 11468 |
| SUOX | 11441 |
| PITPNM3 | 11438 |
| SLC25A11 | 11420 |
| CYP2U1 | 11416 |
| ENTPD6 | 11409 |
| SP1 | 11396 |
| NPAS2 | 11394 |
| RAB5A | 11392 |
| PLIN3 | 11389 |
| NUP35 | 11387 |
| PSMD14 | 11371 |
| ALDOC | 11365 |
| IVD | 11363 |
| PLEKHA6 | 11356 |
| ENTPD4 | 11341 |
| VAC14 | 11319 |
| PNPLA2 | 11306 |
| AASDHPPT | 11292 |
| GCH1 | 11288 |
| PSMD1 | 11280 |
| SERINC3 | 11266 |
| ST3GAL3 | 11257 |
| ELOVL1 | 11234 |
| CTPS1 | 11224 |
| MAN2B2 | 11205 |
| ACSM2A | 11198 |
| GLS | 11183 |
| PC | 11179 |
| MED13 | 11168 |
| NFS1 | 11157 |
| NUP205 | 11144 |
| AZIN2 | 11132 |
| PARP10 | 11125 |
| NMRAL1 | 11123 |
| MOGAT2 | 11122 |
| ADIPOR1 | 11114 |
| RPL19 | 11094 |
| AHR | 11075 |
| POLD1 | 11069 |
| NUP93 | 11067 |
| HADH | 11065 |
| GPC2 | 11063 |
| MAN2C1 | 11046 |
| DHCR24 | 11041 |
| IDUA | 11033 |
| NDST2 | 11032 |
| PIK3C3 | 11026 |
| PSAP | 11023 |
| CYP3A43 | 11009 |
| PCTP | 10959 |
| FLVCR1 | 10949 |
| ESD | 10938 |
| MED7 | 10922 |
| PPP2CA | 10917 |
| FITM1 | 10904 |
| SMPD4 | 10896 |
| PPCS | 10893 |
| CHPT1 | 10889 |
| DDAH1 | 10885 |
| PPP1CA | 10883 |
| LIAS | 10877 |
| DECR2 | 10859 |
| RPS7 | 10850 |
| PKM | 10849 |
| TYMS | 10848 |
| NDUFS4 | 10828 |
| GGCT | 10820 |
| FXN | 10818 |
| IP6K1 | 10812 |
| RBKS | 10789 |
| ELOVL5 | 10783 |
| RFK | 10777 |
| CYP11A1 | 10772 |
| MIOX | 10766 |
| VAMP2 | 10744 |
| BCKDK | 10733 |
| NT5M | 10722 |
| UBA52 | 10707 |
| MED30 | 10702 |
| CERS4 | 10687 |
| GAMT | 10677 |
| MED20 | 10676 |
| ACADS | 10658 |
| LRP10 | 10655 |
| NDUFS7 | 10649 |
| CSNK2A1 | 10637 |
| AGPS | 10633 |
| SLC16A3 | 10630 |
| COX5A | 10625 |
| RPL11 | 10624 |
| RPL10 | 10608 |
| EXT2 | 10604 |
| GPT2 | 10601 |
| SLC37A4 | 10598 |
| PIAS4 | 10596 |
| ACER2 | 10591 |
| HIBCH | 10572 |
| STARD5 | 10571 |
| RPS15 | 10567 |
| VNN1 | 10554 |
| ACOT8 | 10550 |
| CIDEC | 10542 |
| UQCRFS1 | 10539 |
| RRM1 | 10529 |
| PDHX | 10522 |
| NUP188 | 10521 |
| FAU | 10520 |
| CPT2 | 10519 |
| TACO1 | 10511 |
| RPL14 | 10500 |
| GGPS1 | 10498 |
| GPT | 10497 |
| COQ10A | 10484 |
| TECR | 10471 |
| NDUFA1 | 10465 |
| CKM | 10459 |
| ALDH1A1 | 10453 |
| PSMB9 | 10430 |
| SLC27A1 | 10421 |
| ALDH18A1 | 10420 |
| MLX | 10413 |
| ABCC5 | 10405 |
| NUDT16 | 10392 |
| GPI | 10361 |
| NOS3 | 10359 |
| NDUFB4 | 10351 |
| VAPA | 10346 |
| SLC25A44 | 10345 |
| MTMR14 | 10343 |
| BSG | 10339 |
| PSMB6 | 10326 |
| PFKL | 10325 |
| MMADHC | 10322 |
| TTPA | 10319 |
| MED26 | 10313 |
| ACY3 | 10311 |
| PSMC6 | 10307 |
| B3GALT6 | 10295 |
| ENO1 | 10290 |
| B4GALT3 | 10265 |
| SLC19A3 | 10263 |
| SGMS1 | 10257 |
| PPCDC | 10221 |
| ST6GALNAC6 | 10212 |
| ABHD5 | 10203 |
| PGK1 | 10198 |
| PSMC4 | 10196 |
| PARP14 | 10194 |
| SLC35B3 | 10191 |
| TMEM86B | 10186 |
| MINPP1 | 10179 |
| SLC25A15 | 10167 |
| PFKP | 10139 |
| RPS5 | 10135 |
| NUP88 | 10134 |
| IDS | 10121 |
| NUDT12 | 10119 |
| PIK3CD | 10102 |
| MED15 | 10099 |
| DPYD | 10094 |
| NDUFAF3 | 10080 |
| SC5D | 10071 |
| ECI2 | 10067 |
| NDUFB1 | 10065 |
| PPP2R1A | 10064 |
| DERA | 10063 |
| HMOX2 | 10061 |
| CDS1 | 10059 |
| OPLAH | 10049 |
| NUP50 | 10047 |
| ACBD5 | 10037 |
| ENTPD2 | 10034 |
| PTEN | 10023 |
| PCYT2 | 10019 |
| FAHD1 | 10013 |
| ACAD11 | 10011 |
| APOC2 | 9992 |
| GM2A | 9989 |
| RPS11 | 9977 |
| GLIPR1 | 9959 |
| CD36 | 9953 |
| ABCD4 | 9940 |
| ENOPH1 | 9938 |
| AACS | 9934 |
| NUDT13 | 9919 |
| NCOA1 | 9914 |
| RPS19 | 9909 |
| ACSL6 | 9898 |
| GNPDA2 | 9896 |
| ADA | 9894 |
| RPS28 | 9891 |
| STARD3 | 9872 |
| PDP2 | 9869 |
| TRAP1 | 9867 |
| NUBP1 | 9866 |
| LDLR | 9855 |
| PSMD9 | 9853 |
| MED17 | 9850 |
| CHD9 | 9842 |
| GGT7 | 9832 |
| ALDH1B1 | 9831 |
| SULT1A4 | 9821 |
| NR1D1 | 9818 |
| AHRR | 9804 |
| CYP39A1 | 9791 |
| HSD17B10 | 9788 |
| ASAH2 | 9785 |
| PGM1 | 9783 |
| CHST6 | 9782 |
| GPC1 | 9776 |
| ALDH7A1 | 9768 |
| GSTA2 | 9767 |
| LPCAT1 | 9761 |
| EBP | 9739 |
| ALDH3A2 | 9706 |
| CKMT2 | 9686 |
| NUDT7 | 9681 |
| GMPS | 9677 |
| PSMD5 | 9676 |
| SERINC1 | 9659 |
| CSNK2A2 | 9641 |
| NMNAT1 | 9639 |
| FABP1 | 9636 |
| NFYB | 9634 |
| CBS | 9632 |
| SLC35D2 | 9628 |
| BGN | 9620 |
| ARSD | 9613 |
| GPS2 | 9607 |
| PPP2CB | 9606 |
| ST3GAL2 | 9594 |
| COX8A | 9591 |
| GNB2 | 9583 |
| NQO1 | 9580 |
| AGMAT | 9556 |
| MOCS3 | 9550 |
| ORMDL3 | 9537 |
| NME3 | 9525 |
| NDUFAF1 | 9523 |
| OSBPL10 | 9510 |
| COQ3 | 9503 |
| NDUFAF5 | 9498 |
| ADH5 | 9486 |
| FBP1 | 9481 |
| SEH1L | 9474 |
| EPM2A | 9471 |
| AGPAT3 | 9468 |
| PFKM | 9464 |
| ADPRM | 9459 |
| COQ9 | 9456 |
| ITPK1 | 9412 |
| ENPP7 | 9404 |
| FAM120B | 9402 |
| UQCRB | 9401 |
| MLXIPL | 9399 |
| NDUFAF6 | 9386 |
| PI4KA | 9385 |
| PHKA1 | 9383 |
| STS | 9373 |
| PSMD7 | 9371 |
| HSP90AB1 | 9363 |
| NQO2 | 9360 |
| PSMD10 | 9356 |
| QDPR | 9341 |
| NCOR2 | 9331 |
| CHDH | 9330 |
| GLB1L | 9326 |
| GSTZ1 | 9312 |
| NAGLU | 9309 |
| IMPDH2 | 9308 |
| GSTK1 | 9301 |
| PYGL | 9295 |
| RPLP1 | 9291 |
| RIMKLA | 9282 |
| MMACHC | 9266 |
| ALDH1L1 | 9262 |
| PIK3R1 | 9259 |
| ABHD14B | 9257 |
| NCOR1 | 9256 |
| PSMB7 | 9253 |
| AHCYL1 | 9245 |
| RPS12 | 9239 |
| PUDP | 9233 |
| FUT4 | 9232 |
| MT-ND1 | 9229 |
| COX7A2L | 9228 |
| MIGA1 | 9221 |
| LRP8 | 9195 |
| MED9 | 9189 |
| SULT1C2 | 9188 |
| CHSY1 | 9172 |
| HEXA | 9171 |
| HSD17B8 | 9165 |
| ITPR1 | 9146 |
| STAR | 9140 |
| ADCY1 | 9122 |
| GCSH | 9108 |
| OSBPL3 | 9104 |
| NUP155 | 9102 |
| AGXT | 9091 |
| OSBPL9 | 9090 |
| HELZ2 | 9086 |
| HS3ST3A1 | 9084 |
| RPL27A | 9081 |
| NCOA2 | 9072 |
| STARD4 | 9071 |
| RPLP0 | 9067 |
| MTMR12 | 9063 |
| ITPKC | 9060 |
| RIDA | 9058 |
| NNT | 9057 |
| ALDH1L2 | 9050 |
| AGPAT2 | 9047 |
| TBXAS1 | 9044 |
| CDK8 | 9040 |
| AIP | 9029 |
| SRD5A3 | 9027 |
| UBB | 9013 |
| ACADSB | 8978 |
| CPTP | 8966 |
| GATM | 8959 |
| PLA2G4B | 8953 |
| SLC19A1 | 8951 |
| PLPP6 | 8931 |
| AOC3 | 8929 |
| GAA | 8919 |
| CYP26B1 | 8914 |
| TPH1 | 8911 |
| PSMA4 | 8902 |
| BTD | 8893 |
| NR1H3 | 8878 |
| ACER3 | 8870 |
| FPGS | 8866 |
| SLC44A3 | 8864 |
| MED13L | 8847 |
| VKORC1L1 | 8845 |
| ARG1 | 8835 |
| SAMD8 | 8833 |
| PEX11A | 8829 |
| AK9 | 8821 |
| RPL35A | 8797 |
| AK7 | 8795 |
| B3GNT3 | 8781 |
| NT5C | 8771 |
| IP6K2 | 8767 |
| PPP2R1B | 8759 |
| UCK2 | 8752 |
| PDK4 | 8724 |
| HMOX1 | 8715 |
| MED11 | 8686 |
| GNPDA1 | 8671 |
| PSMD4 | 8670 |
| RTEL1 | 8668 |
| ACLY | 8659 |
| PSMC5 | 8646 |
| CHP1 | 8645 |
| RPL30 | 8630 |
| HGD | 8620 |
| ESYT3 | 8615 |
| COQ6 | 8608 |
| RXRA | 8607 |
| KCNJ11 | 8545 |
| GPCPD1 | 8532 |
| COX4I1 | 8531 |
| RPS9 | 8515 |
| EEF1E1 | 8489 |
| GGT5 | 8488 |
| COX14 | 8475 |
| PITPNM2 | 8457 |
| TAZ | 8445 |
| CRAT | 8427 |
| INPP5F | 8411 |
| NUBP2 | 8405 |
| NME2 | 8403 |
| GNG7 | 8395 |
| FECH | 8388 |
| NUDT15 | 8382 |
| RPL18 | 8381 |
| CSNK2B | 8368 |
| SYNJ1 | 8367 |
| ZDHHC21 | 8365 |
| LIPT1 | 8359 |
| MTF1 | 8354 |
| RAE1 | 8335 |
| HILPDA | 8332 |
| SPR | 8323 |
| SLCO1B3 | 8303 |
| TK2 | 8295 |
| GBE1 | 8293 |
| PGM2L1 | 8291 |
| TTR | 8283 |
| ABHD3 | 8280 |
| FUT11 | 8276 |
| PYCR2 | 8272 |
| PNPLA4 | 8265 |
| PCYT1A | 8255 |
| SAMHD1 | 8254 |
| CYP21A2 | 8249 |
| GNAI2 | 8246 |
| FUT10 | 8242 |
| HSD17B2 | 8238 |
| CYP4V2 | 8236 |
| G6PD | 8221 |
| CREBBP | 8214 |
| NDUFB5 | 8211 |
| GPC6 | 8195 |
| RPL26L1 | 8188 |
| TRMT112 | 8181 |
| COX7B | 8175 |
| NDUFA7 | 8174 |
| HS3ST3B1 | 8172 |
| PSMD12 | 8163 |
| NUDT1 | 8144 |
| MTHFS | 8136 |
| RPS29 | 8133 |
| RPL6 | 8132 |
| ADCY9 | 8130 |
| PARP16 | 8129 |
| NDUFS1 | 8126 |
| ACY1 | 8112 |
| ACSBG1 | 8106 |
| PTDSS2 | 8095 |
| SDC3 | 8055 |
| PSME3 | 8052 |
| PLEKHA5 | 8030 |
| ALDH2 | 8012 |
| UQCRC2 | 8002 |
| FUT2 | 8000 |
| ETHE1 | 7998 |
| CYP27A1 | 7994 |
| GPC3 | 7971 |
| NDUFAF7 | 7970 |
| NUP85 | 7946 |
| PLCG2 | 7942 |
| NUP98 | 7940 |
| DLD | 7922 |
| COQ7 | 7920 |
| NDUFA5 | 7919 |
| ACADVL | 7903 |
| MMS19 | 7900 |
| PLCH2 | 7887 |
| GPX4 | 7884 |
| PAOX | 7870 |
| COX19 | 7838 |
| CPNE1 | 7836 |
| GNG5 | 7830 |
| ENO2 | 7826 |
| HNMT | 7819 |
| APOA5 | 7816 |
| B4GAT1 | 7803 |
| MTAP | 7801 |
| IDH3B | 7796 |
| CD320 | 7781 |
| CHST9 | 7776 |
| B4GALT7 | 7764 |
| APOE | 7759 |
| BDH1 | 7748 |
| DGUOK | 7742 |
| SLC16A1 | 7693 |
| SDSL | 7688 |
| PPP1CB | 7685 |
| BCAT2 | 7684 |
| PLD2 | 7673 |
| ACAA2 | 7672 |
| BCAT1 | 7652 |
| SIN3B | 7646 |
| TIMMDC1 | 7636 |
| FABP5 | 7635 |
| TXN | 7626 |
| PGS1 | 7623 |
| CA5B | 7621 |
| DLST | 7611 |
| BAAT | 7606 |
| GOT2 | 7596 |
| LIPT2 | 7595 |
| ISCA1 | 7589 |
| PLCD1 | 7585 |
| HOGA1 | 7531 |
| GCHFR | 7521 |
| TKT | 7520 |
| AZIN1 | 7519 |
| SREBF1 | 7517 |
| ENTPD5 | 7507 |
| RRM2 | 7504 |
| RPL28 | 7500 |
| TNFAIP8 | 7470 |
| INPP5D | 7467 |
| GSR | 7463 |
| SLC25A32 | 7453 |
| DCXR | 7446 |
| FLAD1 | 7436 |
| RPSA | 7435 |
| AADAT | 7398 |
| MTMR9 | 7392 |
| ACAA1 | 7384 |
| SGMS2 | 7378 |
| ELOVL7 | 7372 |
| THRAP3 | 7364 |
| PDPR | 7351 |
| MPC2 | 7337 |
| CPT1B | 7323 |
| AGPAT1 | 7309 |
| RPL8 | 7307 |
| RPS4X | 7297 |
| RPS2 | 7293 |
| ITPA | 7279 |
| IPPK | 7267 |
| RPL29 | 7265 |
| RPL32 | 7263 |
| STXBP1 | 7252 |
| TMEM55B | 7246 |
| GYS1 | 7238 |
| RPL36 | 7221 |
| NDST1 | 7217 |
| COX18 | 7215 |
| ACOT7 | 7200 |
| RPL37 | 7194 |
| CARNMT1 | 7188 |
| PLIN1 | 7186 |
| PAH | 7178 |
| PPP1CC | 7149 |
| SBF1 | 7143 |
| RBP1 | 7136 |
| NOSIP | 7133 |
| PAPSS1 | 7130 |
| SRM | 7127 |
| LPCAT3 | 7121 |
| OSBPL7 | 7117 |
| CACNB3 | 7109 |
| RPS17 | 7104 |
| PTGES3 | 7103 |
| ACOX3 | 7093 |
| KYAT3 | 7091 |
| UBIAD1 | 7066 |
| RPS24 | 7060 |
| MAOB | 7055 |
| CYB5A | 7052 |
| IYD | 7048 |
| NDUFA2 | 7032 |
| NT5C3A | 7021 |
| MBTPS2 | 7019 |
| UGT2B10 | 7015 |
| HAAO | 7005 |
| AMD1 | 6999 |
| SULT1A2 | 6998 |
| CSGALNACT1 | 6991 |
| PANK4 | 6986 |
| BPGM | 6969 |
| CYP3A4 | 6964 |
| EEFSEC | 6962 |
| RAB14 | 6952 |
| NDUFS2 | 6936 |
| LCLAT1 | 6935 |
| PIPOX | 6928 |
| ETNK2 | 6918 |
| SLC23A2 | 6913 |
| MAOA | 6912 |
| PFKFB3 | 6897 |
| PON3 | 6884 |
| PTGES2 | 6882 |
| SPTLC1 | 6875 |
| TIAM2 | 6863 |
| SLC35D1 | 6862 |
| SCD5 | 6855 |
| ARNT2 | 6853 |
| RPS14 | 6851 |
| PPARGC1B | 6846 |
| PLPP1 | 6845 |
| MCAT | 6837 |
| ST3GAL6 | 6829 |
| MANBA | 6817 |
| CYP2E1 | 6804 |
| PLD6 | 6800 |
| GNB1 | 6796 |
| VAPB | 6785 |
| PIP5K1C | 6778 |
| OSBPL8 | 6767 |
| SLC25A17 | 6764 |
| OXCT2 | 6756 |
| AKR1C4 | 6744 |
| NAXD | 6743 |
| CMPK1 | 6740 |
| B3GAT3 | 6727 |
| CARM1 | 6725 |
| VKORC1 | 6714 |
| MED18 | 6710 |
| NMRK1 | 6709 |
| PI4K2A | 6701 |
| MED12 | 6690 |
| CYP2R1 | 6680 |
| TMEM186 | 6678 |
| MT-ND3 | 6674 |
| LBR | 6666 |
| RPS27L | 6664 |
| PPARG | 6636 |
| DPEP1 | 6625 |
| PLPP3 | 6619 |
| COX6B1 | 6617 |
| RPS10 | 6612 |
| ACO2 | 6598 |
| STK11 | 6595 |
| ADHFE1 | 6592 |
| ENO3 | 6590 |
| SPHK1 | 6587 |
| DBT | 6586 |
| SEM1 | 6566 |
| NRF1 | 6553 |
| PNPLA7 | 6544 |
| DCK | 6537 |
| MLYCD | 6512 |
| CHKB | 6506 |
| CA5A | 6505 |
| APRT | 6499 |
| PDZD11 | 6494 |
| COX6A1 | 6487 |
| LYPLA1 | 6485 |
| CRYM | 6463 |
| SULT1B1 | 6435 |
| PSMA3 | 6422 |
| NAALAD2 | 6414 |
| TPI1 | 6413 |
| PMVK | 6407 |
| MT-ND5 | 6406 |
| PIK3C2B | 6385 |
| ALDH9A1 | 6372 |
| NUP54 | 6371 |
| PRKAA2 | 6357 |
| CPNE3 | 6354 |
| HS2ST1 | 6339 |
| XYLB | 6334 |
| ALAS1 | 6320 |
| RPS15A | 6295 |
| SCO1 | 6294 |
| PRKD2 | 6289 |
| CKB | 6276 |
| PTS | 6274 |
| DIO1 | 6269 |
| PARP8 | 6264 |
| ETNPPL | 6239 |
| RPL7 | 6223 |
| RPL34 | 6203 |
| SAR1B | 6198 |
| SORD | 6184 |
| APOB | 6172 |
| AKT1 | 6160 |
| ACBD7 | 6158 |
| GSTM1 | 6155 |
| MTMR6 | 6138 |
| UROD | 6113 |
| CHST7 | 6111 |
| PSMD8 | 6091 |
| GPX1 | 6089 |
| GSS | 6088 |
| RPS21 | 6082 |
| ADSL | 6079 |
| ACOT1 | 6078 |
| TCN2 | 6075 |
| CRLS1 | 6066 |
| MT-ND4 | 6063 |
| PLCD3 | 6050 |
| AGPAT5 | 6047 |
| DHRS7B | 6034 |
| RPS16 | 6026 |
| PDP1 | 5987 |
| RPS3 | 5985 |
| ME2 | 5980 |
| TPST2 | 5975 |
| RPIA | 5974 |
| PANK1 | 5973 |
| RPL13A | 5970 |
| ALB | 5965 |
| RPLP2 | 5950 |
| RPL35 | 5927 |
| SLC25A19 | 5918 |
| FDXR | 5910 |
| AK1 | 5909 |
| LRP12 | 5904 |
| HSCB | 5900 |
| CA3 | 5889 |
| FH | 5877 |
| ADCY6 | 5862 |
| PIK3CA | 5849 |
| AKAP5 | 5848 |
| COX15 | 5828 |
| MT-ND6 | 5803 |
| RPS27A | 5776 |
| SLC6A8 | 5773 |
| KYNU | 5772 |
| NDUFA3 | 5766 |
| FUT6 | 5760 |
| NDUFB7 | 5754 |
| ELOVL2 | 5746 |
| SERINC2 | 5745 |
| MED27 | 5729 |
| AAAS | 5701 |
| ACAD9 | 5691 |
| PPM1L | 5684 |
| MED23 | 5679 |
| ENPP1 | 5660 |
| SEC23A | 5659 |
| PSMA5 | 5657 |
| PLA2G15 | 5653 |
| QPRT | 5648 |
| PANK2 | 5634 |
| HADHA | 5626 |
| LRP1 | 5613 |
| MED4 | 5601 |
| RPL23A | 5592 |
| RPL10A | 5584 |
| RPS6 | 5569 |
| NMNAT3 | 5561 |
| SLC36A4 | 5557 |
| B4GALT6 | 5555 |
| ARSA | 5552 |
| GPD1L | 5544 |
| RPL36A | 5542 |
| SLC44A5 | 5540 |
| GSTO2 | 5526 |
| NAT8L | 5510 |
| RPS18 | 5504 |
| UQCRQ | 5498 |
| HAGH | 5493 |
| CNDP2 | 5485 |
| ADSS | 5475 |
| RPL41 | 5472 |
| OAZ1 | 5465 |
| HSD3B7 | 5445 |
| GMPR2 | 5440 |
| PLEKHA2 | 5432 |
| INPP5E | 5431 |
| SGPP1 | 5415 |
| NUP43 | 5410 |
| PRPS2 | 5393 |
| PIK3CB | 5379 |
| RPS13 | 5366 |
| SDHD | 5358 |
| PSMD13 | 5353 |
| CIAPIN1 | 5343 |
| RPL4 | 5324 |
| DSE | 5314 |
| ACSS3 | 5303 |
| INPP5J | 5266 |
| NUBPL | 5258 |
| PLCE1 | 5235 |
| CYC1 | 5234 |
| DEGS2 | 5232 |
| NUP153 | 5230 |
| PXMP2 | 5225 |
| SLC22A1 | 5220 |
| CHST3 | 5217 |
| UGT1A1 | 5176 |
| GNAI1 | 5167 |
| B4GALT2 | 5152 |
| MPST | 5144 |
| NFYA | 5142 |
| CCNC | 5121 |
| RPS23 | 5114 |
| GSTM3 | 5108 |
| PIP4K2B | 5102 |
| PAICS | 5093 |
| GC | 5084 |
| ACBD6 | 5076 |
| AKR7A2 | 5073 |
| RPL37A | 5072 |
| ARF3 | 5040 |
| AKR7L | 5039 |
| HYAL1 | 5029 |
| B4GALT4 | 5027 |
| COMT | 5019 |
| HSD17B7 | 5017 |
| PLCB3 | 4999 |
| LRAT | 4994 |
| SLC26A2 | 4985 |
| PSMC2 | 4948 |
| PDSS1 | 4946 |
| GALE | 4935 |
| RETSAT | 4932 |
| MTHFD2L | 4929 |
| STX1A | 4922 |
| AGRN | 4911 |
| MCCC2 | 4899 |
| AOC2 | 4896 |
| CERS1 | 4891 |
| B3GNT2 | 4879 |
| SPHK2 | 4877 |
| SLC6A11 | 4870 |
| SLC25A27 | 4866 |
| PSME1 | 4861 |
| PLCG1 | 4855 |
| ACAT1 | 4838 |
| NCOA3 | 4825 |
| COA1 | 4821 |
| SPTSSA | 4796 |
| AK6 | 4794 |
| MORC2 | 4784 |
| NDUFB3 | 4780 |
| TPMT | 4759 |
| ABCA1 | 4752 |
| FDX1 | 4743 |
| GALC | 4735 |
| PIK3R3 | 4734 |
| UQCRH | 4733 |
| RPL39 | 4713 |
| PRKCA | 4709 |
| ABCG2 | 4707 |
| NDUFB11 | 4671 |
| BCO2 | 4667 |
| LPGAT1 | 4666 |
| PODXL2 | 4657 |
| HSD17B1 | 4656 |
| CYP24A1 | 4653 |
| RPL18A | 4649 |
| PDK1 | 4644 |
| PPA2 | 4640 |
| CYP4F12 | 4627 |
| RPL7A | 4625 |
| TNFAIP8L1 | 4624 |
| PDK3 | 4617 |
| GDPD5 | 4613 |
| STARD7 | 4611 |
| PEMT | 4605 |
| NUP58 | 4603 |
| NDUFB2 | 4598 |
| OAZ3 | 4577 |
| MTMR3 | 4570 |
| MTMR10 | 4553 |
| NDUFV2 | 4527 |
| BHMT | 4522 |
| NDUFA13 | 4521 |
| UGT8 | 4511 |
| FAH | 4507 |
| PLCH1 | 4504 |
| NDUFS5 | 4495 |
| TNFRSF21 | 4491 |
| PIKFYVE | 4479 |
| MGST1 | 4472 |
| SMARCD3 | 4455 |
| RAB4A | 4453 |
| SDC4 | 4450 |
| ETNK1 | 4448 |
| EXT1 | 4444 |
| CHST12 | 4437 |
| BHMT2 | 4435 |
| ENTPD8 | 4429 |
| DGAT2 | 4420 |
| TST | 4409 |
| GSTO1 | 4401 |
| TPST1 | 4399 |
| RPS4Y1 | 4388 |
| PPP2R5D | 4385 |
| ITPR2 | 4366 |
| ASPA | 4358 |
| TMEM126B | 4349 |
| MED28 | 4339 |
| GCLM | 4335 |
| CBSL | 4315 |
| B3GAT2 | 4305 |
| ACSF3 | 4297 |
| GCDH | 4269 |
| RPL27 | 4268 |
| SUCLG2 | 4243 |
| MBOAT7 | 4241 |
| AGL | 4233 |
| AKR1D1 | 4223 |
| LYRM4 | 4217 |
| SLC44A1 | 4205 |
| SDC1 | 4201 |
| INMT | 4197 |
| PGP | 4194 |
| TGS1 | 4181 |
| RPL22 | 4170 |
| CHSY3 | 4151 |
| GSTT2B | 4147 |
| CDO1 | 4133 |
| NDUFAB1 | 4114 |
| MED6 | 4113 |
| ALDH4A1 | 4105 |
| GLRX5 | 4064 |
| SLCO1A2 | 4048 |
| PLEKHA1 | 4043 |
| SELENOI | 4039 |
| HPD | 4035 |
| HYAL3 | 4023 |
| SLC25A14 | 4017 |
| AGK | 4016 |
| ETFB | 4002 |
| AHCY | 3991 |
| SLC22A5 | 3989 |
| MGST3 | 3973 |
| UQCR11 | 3967 |
| NUP214 | 3957 |
| MOCS2 | 3956 |
| SUCLG1 | 3936 |
| AKR7A3 | 3934 |
| PTPMT1 | 3929 |
| PSMB3 | 3928 |
| RPL23 | 3923 |
| GGT6 | 3902 |
| HYAL2 | 3890 |
| ALDOB | 3886 |
| OAZ2 | 3878 |
| LIPH | 3871 |
| PHKB | 3861 |
| NADK2 | 3854 |
| HSD17B4 | 3810 |
| MMAA | 3808 |
| CDIPT | 3801 |
| MTHFR | 3788 |
| GNB4 | 3781 |
| SERPINA6 | 3759 |
| PIP5K1A | 3743 |
| B3GNT4 | 3741 |
| NDUFB8 | 3733 |
| PI4KB | 3711 |
| DDHD1 | 3709 |
| RRM2B | 3700 |
| NAMPT | 3699 |
| FASN | 3698 |
| IMPDH1 | 3690 |
| RPL24 | 3686 |
| PSMB2 | 3678 |
| RPL38 | 3652 |
| CHST15 | 3643 |
| GPHN | 3623 |
| ORMDL2 | 3614 |
| HLCS | 3609 |
| PRKAB2 | 3594 |
| RPS20 | 3578 |
| RPL26 | 3560 |
| PDHB | 3550 |
| MDH1 | 3541 |
| SMPD1 | 3537 |
| APIP | 3520 |
| AIMP1 | 3508 |
| FHL2 | 3504 |
| ACSL5 | 3496 |
| PCCB | 3460 |
| FITM2 | 3457 |
| PRKACA | 3407 |
| ACSM1 | 3400 |
| SPTLC2 | 3399 |
| AADAC | 3391 |
| MT-ND2 | 3387 |
| CA13 | 3377 |
| CLOCK | 3360 |
| CIAO1 | 3355 |
| MAT2B | 3339 |
| UPB1 | 3336 |
| SMS | 3332 |
| PRPS1 | 3321 |
| TBL1X | 3308 |
| SYNJ2 | 3280 |
| SLC25A16 | 3248 |
| ACOXL | 3244 |
| SRD5A1 | 3243 |
| ALDH6A1 | 3242 |
| UMPS | 3221 |
| DLAT | 3193 |
| PARP6 | 3181 |
| NDUFB10 | 3165 |
| UCKL1 | 3156 |
| PPA1 | 3152 |
| KCNB1 | 3146 |
| PSTK | 3136 |
| CYP7A1 | 3133 |
| B3GNT7 | 3122 |
| MDH2 | 3120 |
| IPMK | 3118 |
| SLC2A3 | 3116 |
| IDH3A | 3112 |
| SUMO2 | 3089 |
| PSMC3 | 3070 |
| GLB1 | 3064 |
| PAPSS2 | 3052 |
| SLC27A5 | 3043 |
| CS | 3037 |
| NDC1 | 3023 |
| PANK3 | 3009 |
| COX11 | 3007 |
| PDSS2 | 2993 |
| CDK19 | 2984 |
| POR | 2976 |
| SLC25A28 | 2968 |
| MED14 | 2943 |
| GDA | 2932 |
| COX7C | 2931 |
| BLVRA | 2921 |
| SGSH | 2908 |
| PLEKHA4 | 2901 |
| OSBPL6 | 2900 |
| PRKACB | 2885 |
| PTGIS | 2883 |
| PRODH | 2872 |
| CERK | 2848 |
| CTRC | 2844 |
| PYCR1 | 2835 |
| ODC1 | 2823 |
| PLA2G4C | 2813 |
| TBL1XR1 | 2795 |
| PPIP5K1 | 2792 |
| SLC35B2 | 2785 |
| B4GALNT2 | 2758 |
| RPL21 | 2755 |
| HAS3 | 2751 |
| PIK3R2 | 2728 |
| HACL1 | 2718 |
| MED19 | 2717 |
| PRKD3 | 2712 |
| NUP133 | 2708 |
| PRKD1 | 2704 |
| RPE | 2670 |
| GLTP | 2660 |
| RHD | 2658 |
| PPT1 | 2656 |
| UBE2I | 2653 |
| KDSR | 2642 |
| D2HGDH | 2641 |
| RPL15 | 2637 |
| HSD17B13 | 2635 |
| PFKFB1 | 2623 |
| UROS | 2540 |
| NDUFA12 | 2537 |
| NDOR1 | 2526 |
| ARSK | 2519 |
| DDAH2 | 2507 |
| AUH | 2497 |
| GUSB | 2493 |
| EPHX1 | 2481 |
| PDHA1 | 2478 |
| MED25 | 2466 |
| MTRR | 2447 |
| PLD3 | 2446 |
| SBF2 | 2408 |
| SDHA | 2403 |
| UGCG | 2377 |
| GYG1 | 2373 |
| RPL3 | 2369 |
| CROT | 2357 |
| ACHE | 2348 |
| PSMB4 | 2330 |
| CSNK1G2 | 2329 |
| IDH2 | 2314 |
| MED10 | 2313 |
| RPL17 | 2280 |
| NDUFAF4 | 2261 |
| NADK | 2258 |
| PIK3R4 | 2219 |
| RPS8 | 2190 |
| PI4K2B | 2175 |
| G6PC3 | 2174 |
| SLC25A10 | 2172 |
| GK | 2160 |
| SUMF2 | 2158 |
| AKR1A1 | 2156 |
| MTHFD2 | 2153 |
| PRKAR1B | 2113 |
| OSBPL1A | 2101 |
| AIMP2 | 2099 |
| HSP90AA1 | 2096 |
| VDAC1 | 2092 |
| SHPK | 2085 |
| NDUFB6 | 2079 |
| NDUFS8 | 2075 |
| MARCKS | 2067 |
| PPAT | 2065 |
| GNB3 | 2063 |
| PSMB1 | 2062 |
| CYP2D6 | 2056 |
| PIP5K1B | 2051 |
| GLDC | 2046 |
| SULT1A3 | 2038 |
| NUDT18 | 2017 |
| GYG2 | 2010 |
| RPL12 | 2000 |
| SLC25A21 | 1997 |
| ARNT | 1996 |
| TPK1 | 1978 |
| LGMN | 1966 |
| CBR4 | 1961 |
| STARD3NL | 1953 |
| NAPRT | 1945 |
| PHKG1 | 1941 |
| CKMT1A | 1913 |
| RPS25 | 1901 |
| SUCLA2 | 1889 |
| GPC4 | 1874 |
| DHTKD1 | 1873 |
| COX16 | 1851 |
| PSMA7 | 1820 |
| AMN | 1802 |
| ASMT | 1800 |
| CEPT1 | 1789 |
| NME1 | 1786 |
| SLC25A37 | 1785 |
| ACOX2 | 1774 |
| UQCR10 | 1768 |
| PRKAR2A | 1753 |
| SARDH | 1750 |
| ETFDH | 1746 |
| RXRB | 1725 |
| SMPD3 | 1715 |
| OGDH | 1705 |
| ADPGK | 1704 |
| SLC46A1 | 1702 |
| AMPD3 | 1688 |
| CUBN | 1678 |
| UGT2B11 | 1644 |
| CDS2 | 1637 |
| SLC27A2 | 1635 |
| IDO2 | 1618 |
| PLA2G12A | 1614 |
| BLVRB | 1602 |
| PPARD | 1594 |
| NDUFA8 | 1589 |
| GNAQ | 1588 |
| PON1 | 1585 |
| HMBS | 1579 |
| PPIP5K2 | 1574 |
| UBC | 1551 |
| SLC25A13 | 1525 |
| CYP2J2 | 1505 |
| GDE1 | 1502 |
| PSMB5 | 1484 |
| FABP2 | 1471 |
| PISD | 1470 |
| MTMR1 | 1468 |
| MED21 | 1457 |
| MED24 | 1445 |
| RPL13 | 1426 |
| MT-CO2 | 1414 |
| BST1 | 1408 |
| NFYC | 1395 |
| COX5B | 1393 |
| GNB5 | 1388 |
| DDC | 1382 |
| IMPA1 | 1368 |
| MTMR2 | 1361 |
| ADCY2 | 1356 |
| NDUFA11 | 1353 |
| CALM1 | 1340 |
| GOT1 | 1297 |
| UQCRC1 | 1285 |
| HSD11B2 | 1264 |
| PCBD1 | 1241 |
| ETFA | 1238 |
| MAN2B1 | 1230 |
| ORMDL1 | 1227 |
| CACNA1A | 1224 |
| MED16 | 1198 |
| INPPL1 | 1197 |
| ADH1B | 1195 |
| ERCC2 | 1192 |
| PLIN2 | 1183 |
| CYB5R3 | 1177 |
| ADK | 1168 |
| PGD | 1139 |
| NDUFS3 | 1132 |
| TPR | 1105 |
| PON2 | 1101 |
| CYCS | 1098 |
| DDHD2 | 1093 |
| ADAL | 1092 |
| PRELP | 1073 |
| ATIC | 1065 |
| MTHFD1 | 1043 |
| DBI | 1034 |
| AGMO | 1027 |
| RPL5 | 1001 |
| LYVE1 | 992 |
| CHST5 | 989 |
| TMLHE | 950 |
| HSD17B14 | 944 |
| DCTPP1 | 940 |
| NDUFV1 | 927 |
| PARP4 | 908 |
| CYP4F11 | 904 |
| GNAS | 900 |
| UCP2 | 886 |
| SYT5 | 881 |
| PSMD11 | 879 |
| NDUFA6 | 871 |
| RAPGEF4 | 863 |
| DSEL | 856 |
| ISYNA1 | 846 |
| PSMB10 | 838 |
| SECISBP2 | 831 |
| PHKA2 | 829 |
| RPS26 | 827 |
| SMPD2 | 823 |
| GNPAT | 822 |
| SLC27A3 | 807 |
| NDUFA4 | 795 |
| CYP8B1 | 789 |
| CYP17A1 | 777 |
| PGLS | 770 |
| CYP3A5 | 747 |
| PRKAG2 | 740 |
| ARNTL | 732 |
| SLC37A2 | 727 |
| PLPP2 | 694 |
| BCKDHB | 689 |
| NUP160 | 683 |
| NUDT5 | 678 |
| ECI1 | 669 |
| COX6C | 661 |
| MED31 | 657 |
| RPL31 | 638 |
| NADSYN1 | 635 |
| SURF1 | 631 |
| NUP62 | 618 |
| PHGDH | 606 |
| RAP1A | 604 |
| GNMT | 590 |
| HADHB | 568 |
| FDX2 | 557 |
| CYP2S1 | 548 |
| B4GALT1 | 540 |
| NDUFC1 | 527 |
| ECHS1 | 523 |
| PLEKHA8 | 515 |
| GGT1 | 514 |
| PGM2 | 513 |
| RPL9 | 509 |
| MTM1 | 500 |
| TXN2 | 499 |
| ACP5 | 497 |
| CPOX | 478 |
| ADIPOR2 | 476 |
| GADL1 | 467 |
| CERS5 | 459 |
| APOA4 | 444 |
| RPL22L1 | 439 |
| ABHD4 | 422 |
| GRHPR | 410 |
| INPP4A | 400 |
| LDHA | 384 |
| COQ2 | 375 |
| NR1H2 | 373 |
| HACD1 | 370 |
| RPS3A | 369 |
| PIK3C2A | 365 |
| ENTPD1 | 358 |
| CYP2B6 | 351 |
| CYP46A1 | 347 |
| RPS27 | 312 |
| MED8 | 308 |
| NAT1 | 306 |
| NT5C2 | 296 |
| SDC2 | 289 |
| FMO3 | 281 |
| PSMA6 | 261 |
| PYGM | 255 |
| ACACA | 236 |
| DGAT1 | 222 |
| TSPO | 220 |
| SACM1L | 218 |
| OXCT1 | 203 |
| GART | 193 |
| TNFAIP8L3 | 182 |
| CES2 | 177 |
| NDUFA10 | 173 |
| NUDT9 | 167 |
| SLC44A4 | 151 |
| UCK1 | 142 |
| PSPH | 137 |
| ASS1 | 135 |
| HDAC3 | 84 |
| ABCB7 | 64 |
| SAT1 | 60 |
| AKR1C3 | 54 |
| HTD2 | 47 |
| PFKFB4 | 33 |
| SGPL1 | 10 |
| RANBP2 | 9 |
| PRKAR1A | 6 |
Immune System
| 502 | |
|---|---|
| set | Immune System |
| setSize | 1374 |
| pANOVA | 1.75e-07 |
| s.dist | 0.0855 |
| p.adjustANOVA | 2.41e-05 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SERPING1 | 14532 |
| HSPA5 | 14531 |
| CALR | 14529 |
| SEC24D | 14520 |
| DNAJC3 | 14516 |
| HSP90B1 | 14514 |
| TXNIP | 14509 |
| MUC5B | 14487 |
| SOCS3 | 14476 |
| CANX | 14462 |
| PDIA3 | 14454 |
| VASP | 14437 |
| PLPP5 | 14436 |
| C1S | 14430 |
| KLHL21 | 14429 |
| UBE2J1 | 14428 |
| IL21R | 14424 |
| ATP6V0B | 14422 |
| MAP3K8 | 14418 |
| C3 | 14417 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SERPING1 | 14532 |
| HSPA5 | 14531 |
| CALR | 14529 |
| SEC24D | 14520 |
| DNAJC3 | 14516 |
| HSP90B1 | 14514 |
| TXNIP | 14509 |
| MUC5B | 14487 |
| SOCS3 | 14476 |
| CANX | 14462 |
| PDIA3 | 14454 |
| VASP | 14437 |
| PLPP5 | 14436 |
| C1S | 14430 |
| KLHL21 | 14429 |
| UBE2J1 | 14428 |
| IL21R | 14424 |
| ATP6V0B | 14422 |
| MAP3K8 | 14418 |
| C3 | 14417 |
| NCR3LG1 | 14403 |
| MAGT1 | 14398 |
| CSF3R | 14395 |
| CFB | 14394 |
| CNN2 | 14383 |
| C4A | 14381 |
| SEC61A1 | 14374 |
| C8B | 14372 |
| SOD2 | 14367 |
| ERP44 | 14364 |
| SQSTM1 | 14347 |
| FGA | 14346 |
| EIF4A1 | 14329 |
| SNRPA1 | 14316 |
| LAMP1 | 14314 |
| ATP6V0A1 | 14310 |
| LEAP2 | 14305 |
| SERPINA3 | 14304 |
| CEACAM1 | 14302 |
| JAK3 | 14295 |
| LAMP2 | 14291 |
| RNF125 | 14283 |
| ASB2 | 14280 |
| STX3 | 14279 |
| SEC61B | 14278 |
| PIK3AP1 | 14273 |
| OAS1 | 14269 |
| POLR3GL | 14267 |
| CTSL | 14263 |
| ARSB | 14246 |
| IL17RB | 14244 |
| GGH | 14243 |
| TGFB1 | 14241 |
| CCR6 | 14239 |
| LGALS3 | 14229 |
| ATP6V1D | 14228 |
| SHC1 | 14209 |
| ATP6V0D1 | 14206 |
| CDH1 | 14202 |
| MLEC | 14193 |
| PLD1 | 14191 |
| C4B | 14173 |
| CCL20 | 14171 |
| P4HB | 14170 |
| ATP6V0A2 | 14162 |
| S100A11 | 14143 |
| UBE2L6 | 14134 |
| FBXL16 | 14129 |
| TKFC | 14126 |
| P2RX1 | 14116 |
| GCA | 14108 |
| PLA2G2A | 14102 |
| BRI3 | 14094 |
| ACTG1 | 14090 |
| SEC24A | 14088 |
| FLNA | 14081 |
| GNS | 14052 |
| SEC13 | 14049 |
| PNP | 14046 |
| C8A | 14042 |
| NDUFC2 | 14038 |
| NEDD4L | 14037 |
| TRIB3 | 14029 |
| FGB | 14018 |
| C4BPB | 14006 |
| C5 | 14003 |
| SLA2 | 13986 |
| CYSTM1 | 13982 |
| BTN2A1 | 13956 |
| C1R | 13954 |
| NEU1 | 13953 |
| NFATC3 | 13947 |
| NHLRC3 | 13928 |
| HNRNPF | 13925 |
| VCP | 13902 |
| IRAK2 | 13893 |
| CSF1 | 13888 |
| KPNA1 | 13876 |
| FTL | 13872 |
| PYGB | 13867 |
| SIAH2 | 13819 |
| BTN3A2 | 13815 |
| PSMF1 | 13810 |
| UBE2C | 13793 |
| BTN3A1 | 13787 |
| ASAH1 | 13777 |
| IL1RN | 13768 |
| SOCS5 | 13766 |
| UBE2Q1 | 13760 |
| KIF5A | 13752 |
| ATP6V0E1 | 13731 |
| LMNB1 | 13707 |
| NUP37 | 13706 |
| SURF4 | 13688 |
| RAPGEF1 | 13680 |
| HSPA9 | 13667 |
| TOLLIP | 13662 |
| NF2 | 13642 |
| RALA | 13623 |
| WASL | 13611 |
| DUSP3 | 13608 |
| IGF2R | 13604 |
| FUCA2 | 13600 |
| DNM2 | 13597 |
| A1BG | 13591 |
| DNAJC5 | 13582 |
| CD55 | 13575 |
| RORC | 13571 |
| TMBIM1 | 13533 |
| APP | 13532 |
| VHL | 13531 |
| TRIM5 | 13511 |
| KEAP1 | 13510 |
| NFKBIB | 13495 |
| EP300 | 13485 |
| ALDOA | 13474 |
| MAPKAPK2 | 13468 |
| HEXB | 13459 |
| CLEC10A | 13452 |
| PSME4 | 13450 |
| DDX3X | 13448 |
| HNRNPA2B1 | 13444 |
| CD14 | 13442 |
| ICAM3 | 13436 |
| CLTA | 13432 |
| NFKBIA | 13427 |
| RAB37 | 13426 |
| PSMD2 | 13423 |
| DDOST | 13410 |
| EIF4G2 | 13391 |
| CDK13 | 13387 |
| KCMF1 | 13357 |
| KPNB1 | 13324 |
| PJA2 | 13321 |
| KIF22 | 13293 |
| ARIH2 | 13284 |
| POM121 | 13281 |
| TRAIP | 13276 |
| BCL2L1 | 13271 |
| UBR4 | 13266 |
| DSN1 | 13258 |
| MBL2 | 13247 |
| VTN | 13246 |
| ATAD3B | 13239 |
| UBE2O | 13236 |
| PYCARD | 13221 |
| BTN3A3 | 13210 |
| KIF3B | 13207 |
| CFI | 13206 |
| GALNS | 13205 |
| TRIM45 | 13192 |
| SLC44A2 | 13182 |
| ICAM2 | 13167 |
| CEBPD | 13165 |
| TIMP1 | 13158 |
| CTSA | 13149 |
| ALDH3B1 | 13143 |
| TAX1BP1 | 13141 |
| S100A1 | 13138 |
| PTPN18 | 13128 |
| ATP6V1E1 | 13114 |
| PRDX4 | 13105 |
| CD22 | 13079 |
| LCK | 13069 |
| RBBP6 | 13058 |
| DZIP3 | 13056 |
| SEC24C | 13047 |
| PTK2B | 13043 |
| UBE2J2 | 13040 |
| MAP3K1 | 13035 |
| SMURF1 | 13034 |
| NUP210 | 13025 |
| CLTC | 13017 |
| KBTBD6 | 13016 |
| SH3RF1 | 13005 |
| NPC2 | 12991 |
| KBTBD7 | 12967 |
| IFI30 | 12951 |
| TUBB4B | 12934 |
| ATF2 | 12933 |
| PGAM1 | 12932 |
| RAP2B | 12931 |
| CDA | 12891 |
| HP | 12884 |
| LRG1 | 12875 |
| SMAD3 | 12871 |
| C5AR1 | 12862 |
| IFIT5 | 12858 |
| SYNGR1 | 12842 |
| TRIM26 | 12834 |
| TMC6 | 12813 |
| FGG | 12809 |
| CD63 | 12800 |
| PTPRJ | 12791 |
| TAB1 | 12789 |
| PDXK | 12784 |
| ARPC4 | 12778 |
| IRF9 | 12775 |
| ITCH | 12771 |
| ITPR3 | 12768 |
| ATP6V0C | 12764 |
| CYLD | 12727 |
| MASP1 | 12716 |
| DEGS1 | 12708 |
| OAS3 | 12696 |
| MYLIP | 12695 |
| IFIH1 | 12693 |
| POM121C | 12687 |
| MAPK3 | 12684 |
| LAMA5 | 12680 |
| UBE3C | 12679 |
| TPP2 | 12660 |
| MALT1 | 12658 |
| ARF1 | 12642 |
| C6 | 12636 |
| IFI35 | 12631 |
| COLEC11 | 12595 |
| DUSP4 | 12556 |
| KIF11 | 12553 |
| KIFAP3 | 12544 |
| STAT5B | 12541 |
| HACE1 | 12533 |
| PTPN6 | 12513 |
| PSMD6 | 12502 |
| IKBKG | 12493 |
| FBXW5 | 12489 |
| OTUD5 | 12487 |
| SRP14 | 12470 |
| MAPKAP1 | 12466 |
| MVP | 12465 |
| PRKCSH | 12463 |
| PTPN23 | 12460 |
| ATP6V1C2 | 12453 |
| CCT2 | 12444 |
| BPIFB1 | 12440 |
| BPIFB6 | 12439 |
| ARL8A | 12434 |
| MYO9B | 12432 |
| IL1R1 | 12430 |
| DDX41 | 12428 |
| DNM1 | 12417 |
| RNF130 | 12414 |
| EIF4G1 | 12400 |
| ITGB2 | 12388 |
| UBE2F | 12374 |
| THOP1 | 12370 |
| DOK3 | 12363 |
| RORA | 12360 |
| CD68 | 12316 |
| EIF4G3 | 12310 |
| CAPN1 | 12305 |
| ECSIT | 12282 |
| ADAM17 | 12276 |
| ANO6 | 12256 |
| IFITM3 | 12241 |
| BTN2A2 | 12236 |
| IL34 | 12233 |
| KIF2A | 12231 |
| TRIM22 | 12230 |
| RAB7A | 12220 |
| DIAPH1 | 12211 |
| PSMA2 | 12203 |
| ASB13 | 12175 |
| PVR | 12169 |
| RIPK2 | 12158 |
| IFIT1 | 12148 |
| MAPKAPK3 | 12147 |
| SEC31A | 12138 |
| UBE2G1 | 12134 |
| PPP2R5A | 12088 |
| CFL1 | 12075 |
| ELK1 | 12060 |
| ITGAL | 12056 |
| PSMA1 | 12052 |
| ALAD | 12045 |
| KIF23 | 12032 |
| DET1 | 12028 |
| WASF1 | 12021 |
| RNF144B | 12014 |
| TNFRSF11A | 12009 |
| CBL | 12008 |
| MKRN1 | 11981 |
| SNAP23 | 11956 |
| STAT1 | 11938 |
| TRIM14 | 11936 |
| IQGAP1 | 11931 |
| NLRX1 | 11926 |
| DNASE1L1 | 11920 |
| LRSAM1 | 11916 |
| CRK | 11901 |
| ANAPC7 | 11895 |
| LTA4H | 11893 |
| GLA | 11875 |
| PRKCD | 11872 |
| PANX1 | 11867 |
| POLR3E | 11853 |
| CYFIP2 | 11850 |
| UBA7 | 11821 |
| CCT8 | 11813 |
| TRIM2 | 11801 |
| RNF41 | 11780 |
| PITPNA | 11779 |
| TRIM56 | 11765 |
| ATP6V1B2 | 11744 |
| PSMC1 | 11724 |
| ANXA2 | 11716 |
| RAF1 | 11708 |
| CASP10 | 11704 |
| TALDO1 | 11703 |
| AGA | 11701 |
| HECTD1 | 11699 |
| C6orf120 | 11690 |
| FBXO41 | 11685 |
| MAP3K3 | 11679 |
| HRAS | 11673 |
| MAPK12 | 11663 |
| PSMD3 | 11655 |
| ITGB5 | 11649 |
| CDC23 | 11639 |
| CASP1 | 11631 |
| CDC34 | 11619 |
| CD47 | 11617 |
| TRIM8 | 11611 |
| PRKCE | 11606 |
| GRB10 | 11598 |
| PLA2G6 | 11578 |
| TRIM25 | 11574 |
| THEM4 | 11571 |
| ISG15 | 11568 |
| FBXO31 | 11563 |
| NUP107 | 11561 |
| CD4 | 11557 |
| PSME2 | 11555 |
| CD58 | 11554 |
| ANAPC10 | 11551 |
| LRRFIP1 | 11545 |
| SEC24B | 11541 |
| DHX58 | 11535 |
| POLR2L | 11530 |
| IDH1 | 11528 |
| KIF4A | 11524 |
| SOCS6 | 11523 |
| PROS1 | 11519 |
| DYNLL2 | 11507 |
| FBXW4 | 11502 |
| KIF15 | 11499 |
| IRS2 | 11497 |
| CLEC2D | 11496 |
| MEX3C | 11495 |
| NCF2 | 11446 |
| CISH | 11440 |
| FLT3LG | 11436 |
| BRK1 | 11428 |
| ATP8A1 | 11425 |
| CLCF1 | 11424 |
| KIF5B | 11419 |
| UNKL | 11412 |
| FTH1 | 11406 |
| FBXO17 | 11405 |
| SOS2 | 11402 |
| TNFRSF12A | 11388 |
| NUP35 | 11387 |
| KIF2C | 11386 |
| TRIM32 | 11376 |
| PPM1B | 11375 |
| PSMD14 | 11371 |
| HERC6 | 11369 |
| ALDOC | 11365 |
| POLR2K | 11350 |
| TXNDC5 | 11346 |
| IFIT3 | 11329 |
| PSTPIP1 | 11328 |
| SKP2 | 11323 |
| LONRF1 | 11318 |
| TRAF7 | 11310 |
| MYD88 | 11305 |
| HLA-C | 11297 |
| KIF20A | 11285 |
| ATP6V1G1 | 11283 |
| PSMD1 | 11280 |
| HGSNAT | 11261 |
| PTPN12 | 11236 |
| IQGAP2 | 11231 |
| FBXO32 | 11189 |
| ACTR3 | 11186 |
| RHOA | 11182 |
| MYO10 | 11171 |
| USP18 | 11159 |
| POLR2F | 11158 |
| NUP205 | 11144 |
| ILF2 | 11108 |
| CASP3 | 11107 |
| SMURF2 | 11093 |
| CASP9 | 11084 |
| ASB6 | 11077 |
| NUP93 | 11067 |
| PELI1 | 11028 |
| PIK3C3 | 11026 |
| PSAP | 11023 |
| AP1S1 | 11022 |
| CTSB | 10996 |
| EBI3 | 10994 |
| RACGAP1 | 10990 |
| CEP290 | 10987 |
| SOD1 | 10975 |
| HLA-A | 10971 |
| FKBP1A | 10960 |
| ACTR1B | 10947 |
| MIF | 10935 |
| FOS | 10931 |
| MASP2 | 10923 |
| TBK1 | 10919 |
| PPP2CA | 10917 |
| ACTR1A | 10903 |
| IL10RB | 10890 |
| ISG20 | 10884 |
| PKM | 10849 |
| PPP2R5B | 10834 |
| TRIM36 | 10821 |
| RNF6 | 10809 |
| LBP | 10799 |
| ATP6V0E2 | 10798 |
| SLCO4C1 | 10785 |
| FBXL5 | 10775 |
| VAMP2 | 10744 |
| CTSH | 10743 |
| CDC20 | 10732 |
| AAMP | 10725 |
| CLU | 10723 |
| BLMH | 10712 |
| UBA52 | 10707 |
| MAPK1 | 10705 |
| ACTB | 10683 |
| EEF2 | 10659 |
| NIT2 | 10636 |
| EIF4A2 | 10631 |
| ZAP70 | 10613 |
| RNF213 | 10611 |
| ACTR10 | 10590 |
| ULBP1 | 10573 |
| CFD | 10570 |
| VNN1 | 10554 |
| HMGB1 | 10552 |
| CENPE | 10538 |
| RAP1GAP | 10531 |
| NUP188 | 10521 |
| POLR1C | 10515 |
| XAF1 | 10493 |
| VAMP8 | 10475 |
| BPIFB2 | 10473 |
| TNFSF4 | 10472 |
| JAK1 | 10468 |
| PAK2 | 10458 |
| CAB39 | 10457 |
| ATP6V1C1 | 10444 |
| IL6R | 10440 |
| PSMB9 | 10430 |
| PSEN1 | 10427 |
| NPDC1 | 10426 |
| ATF1 | 10407 |
| NCKIPSD | 10395 |
| DTX3L | 10364 |
| GPI | 10361 |
| NOS3 | 10359 |
| ATG7 | 10354 |
| NOD1 | 10348 |
| VAPA | 10346 |
| PSMB6 | 10326 |
| PFKL | 10325 |
| WSB1 | 10308 |
| PSMC6 | 10307 |
| RAB31 | 10305 |
| KLHL42 | 10303 |
| IL32 | 10276 |
| FOXO1 | 10275 |
| CAPZA1 | 10272 |
| GSDMD | 10266 |
| ORAI2 | 10259 |
| OSTF1 | 10254 |
| OSMR | 10214 |
| CTSK | 10213 |
| RNF19A | 10207 |
| PSMC4 | 10196 |
| TBC1D10C | 10190 |
| MADCAM1 | 10174 |
| UBE2H | 10168 |
| IL1RAP | 10146 |
| IL13RA1 | 10143 |
| NUP88 | 10134 |
| PIK3CD | 10102 |
| SH2B3 | 10091 |
| PTPN9 | 10072 |
| DSP | 10069 |
| SIPA1 | 10068 |
| PPP2R1A | 10064 |
| DERA | 10063 |
| HMOX2 | 10061 |
| TCP1 | 10050 |
| NUP50 | 10047 |
| MYH9 | 10036 |
| PTEN | 10023 |
| MX1 | 10017 |
| STAT5A | 10000 |
| GM2A | 9989 |
| FBXO44 | 9964 |
| GLIPR1 | 9959 |
| CD36 | 9953 |
| RNF123 | 9939 |
| MMP2 | 9932 |
| RILP | 9929 |
| POLR2E | 9916 |
| UBE2V1 | 9900 |
| HSPA8 | 9895 |
| TRIM3 | 9887 |
| KIF18A | 9884 |
| C4BPA | 9865 |
| VAV3 | 9861 |
| FAF2 | 9859 |
| PSMD9 | 9853 |
| RBSN | 9844 |
| TSPAN14 | 9825 |
| IRF1 | 9820 |
| TANK | 9817 |
| AP2M1 | 9787 |
| PGM1 | 9783 |
| NKIRAS2 | 9777 |
| BIRC5 | 9771 |
| GSTA2 | 9767 |
| LPCAT1 | 9761 |
| ASB9 | 9735 |
| GBP2 | 9711 |
| KPNA2 | 9708 |
| OSCAR | 9699 |
| TUBB | 9694 |
| PSMD5 | 9676 |
| KLHL22 | 9610 |
| PPP2CB | 9606 |
| BATF | 9599 |
| POLR1D | 9588 |
| TYK2 | 9579 |
| ICOSLG | 9572 |
| SOCS1 | 9561 |
| MAP2K4 | 9558 |
| TRIP12 | 9551 |
| RNF19B | 9545 |
| VAT1 | 9540 |
| ALPK1 | 9538 |
| ORMDL3 | 9537 |
| CD46 | 9531 |
| PELI3 | 9505 |
| CAT | 9504 |
| ABI1 | 9492 |
| SEH1L | 9474 |
| BCL10 | 9472 |
| EIF4E2 | 9454 |
| COMMD3 | 9446 |
| FBXO21 | 9436 |
| VEGFA | 9433 |
| NLRC5 | 9432 |
| CTSC | 9398 |
| PPIA | 9393 |
| ARPC1B | 9372 |
| PSMD7 | 9371 |
| HSP90AB1 | 9363 |
| ATP6V1H | 9358 |
| PSMD10 | 9356 |
| MAP2K7 | 9311 |
| IMPDH2 | 9308 |
| PYGL | 9295 |
| EPPIN | 9281 |
| MAPK7 | 9270 |
| PIK3R1 | 9259 |
| PSMB7 | 9253 |
| AHCYL1 | 9245 |
| KPNA3 | 9223 |
| MIB2 | 9222 |
| PTK2 | 9198 |
| IL18BP | 9182 |
| UBE2M | 9174 |
| MUC15 | 9153 |
| ITPR1 | 9146 |
| TNFSF12 | 9134 |
| ITGAV | 9120 |
| TNFRSF1A | 9118 |
| FBXL4 | 9111 |
| NUP155 | 9102 |
| TNFRSF13C | 9085 |
| BCL6 | 9080 |
| RPLP0 | 9067 |
| AGPAT2 | 9047 |
| FBXO22 | 9038 |
| AIP | 9029 |
| IL15RA | 9025 |
| UBB | 9013 |
| C7 | 9004 |
| NFATC2 | 8958 |
| TRIM4 | 8937 |
| PLEKHO2 | 8935 |
| RNF126 | 8928 |
| APEH | 8922 |
| GAA | 8919 |
| IL11RA | 8909 |
| PSMA4 | 8902 |
| ANPEP | 8901 |
| AP1S2 | 8889 |
| TOM1 | 8877 |
| ARG1 | 8835 |
| PPP3R1 | 8832 |
| YPEL5 | 8825 |
| ASB1 | 8818 |
| IFI6 | 8808 |
| HIF1A | 8807 |
| XRCC5 | 8806 |
| IP6K2 | 8767 |
| ITGB1 | 8760 |
| PPP2R1B | 8759 |
| KLC1 | 8755 |
| EEF1A1 | 8740 |
| DPP7 | 8739 |
| CUL1 | 8725 |
| GAB2 | 8722 |
| HMOX1 | 8715 |
| MAP2K1 | 8704 |
| RHOU | 8693 |
| CSK | 8692 |
| DHX9 | 8688 |
| PSMD4 | 8670 |
| CAMK2A | 8669 |
| COPB1 | 8664 |
| ACLY | 8659 |
| LCN2 | 8658 |
| TRIM69 | 8652 |
| PIM1 | 8647 |
| PSMC5 | 8646 |
| ATP6V1B1 | 8635 |
| CAP1 | 8634 |
| PTPN14 | 8577 |
| PPP3CB | 8574 |
| SEC61G | 8561 |
| PTAFR | 8514 |
| PLAUR | 8513 |
| ERAP2 | 8507 |
| CD8A | 8470 |
| POLR3D | 8453 |
| UBE2D3 | 8449 |
| UBE3B | 8447 |
| TIRAP | 8439 |
| UBA5 | 8421 |
| CNPY3 | 8413 |
| NME2 | 8403 |
| ORM1 | 8400 |
| ADAR | 8398 |
| IL11 | 8393 |
| DCTN2 | 8375 |
| SARM1 | 8374 |
| CSNK2B | 8368 |
| VCL | 8357 |
| FBXL20 | 8336 |
| RAE1 | 8335 |
| CKAP4 | 8327 |
| SIKE1 | 8322 |
| TIMP2 | 8320 |
| CUL7 | 8310 |
| METTL7A | 8298 |
| TNFAIP3 | 8284 |
| TTR | 8283 |
| SAMHD1 | 8254 |
| DYNC1LI2 | 8235 |
| CPB2 | 8234 |
| ASB7 | 8217 |
| CREBBP | 8214 |
| TAB2 | 8201 |
| DUSP7 | 8185 |
| IL12A | 8182 |
| RAB3A | 8176 |
| PSMD12 | 8163 |
| RPS6KA1 | 8159 |
| FBXO11 | 8152 |
| KLHL13 | 8137 |
| BCL2L11 | 8099 |
| C2 | 8098 |
| STAT3 | 8078 |
| RNF216 | 8077 |
| ASB4 | 8067 |
| CTF1 | 8054 |
| PSME3 | 8052 |
| PTPN2 | 8048 |
| CASP2 | 7990 |
| FBXW11 | 7986 |
| HLA-H | 7975 |
| ATP6V1A | 7965 |
| HUWE1 | 7955 |
| FBXO4 | 7948 |
| NUP85 | 7946 |
| PLCG2 | 7942 |
| NUP98 | 7940 |
| LIFR | 7929 |
| IFNAR1 | 7910 |
| HERC2 | 7888 |
| RBX1 | 7850 |
| CPNE1 | 7836 |
| CNTF | 7828 |
| LAT | 7813 |
| MTAP | 7801 |
| NLRC4 | 7799 |
| TRIM21 | 7792 |
| MTOR | 7785 |
| MCL1 | 7783 |
| MRE11 | 7780 |
| NBEAL2 | 7749 |
| PDAP1 | 7739 |
| GAN | 7702 |
| CD101 | 7697 |
| DCTN5 | 7690 |
| PLD2 | 7673 |
| CPN1 | 7658 |
| SH2B1 | 7640 |
| DYNC1H1 | 7639 |
| RAB24 | 7638 |
| FABP5 | 7635 |
| TXN | 7626 |
| LAG3 | 7625 |
| SERPINA1 | 7622 |
| IL20RB | 7608 |
| TRIM41 | 7599 |
| ROCK1 | 7591 |
| POLR2H | 7590 |
| LIF | 7579 |
| CDKN1A | 7569 |
| TMEM179B | 7543 |
| SRC | 7516 |
| KCTD7 | 7510 |
| ANAPC5 | 7485 |
| SIRPA | 7474 |
| FBXO6 | 7468 |
| INPP5D | 7467 |
| TRIM62 | 7465 |
| COMMD9 | 7455 |
| PRLR | 7452 |
| JUNB | 7447 |
| NFKB1 | 7409 |
| KLC4 | 7401 |
| MYO5A | 7394 |
| AP2A2 | 7391 |
| ACAA1 | 7384 |
| HVCN1 | 7380 |
| SPTBN2 | 7379 |
| IL17RE | 7316 |
| UBE3D | 7298 |
| TRIM37 | 7290 |
| DYNLT1 | 7253 |
| LYZ | 7247 |
| ARPC3 | 7237 |
| TRIM39 | 7228 |
| GOLGA7 | 7208 |
| MAP3K7 | 7172 |
| UBE2A | 7140 |
| IL7 | 7119 |
| DUSP6 | 7113 |
| KLC2 | 7112 |
| UBE2E1 | 7102 |
| CST3 | 7101 |
| WASF2 | 7096 |
| CHUK | 7086 |
| FBXW8 | 7078 |
| STBD1 | 7077 |
| KLHL9 | 7071 |
| HSPA6 | 7061 |
| SIAH1 | 7045 |
| MAP2K3 | 7038 |
| CRLF1 | 7035 |
| ATG12 | 7022 |
| STIM1 | 7007 |
| ATOX1 | 6974 |
| MEF2A | 6959 |
| RAB14 | 6952 |
| RNF14 | 6933 |
| CXCL8 | 6916 |
| MAOA | 6912 |
| FBXO27 | 6911 |
| PTPN1 | 6909 |
| PTGES2 | 6882 |
| TRPC1 | 6877 |
| KLHL2 | 6866 |
| TIFA | 6848 |
| RAP1B | 6830 |
| TRIM11 | 6826 |
| CD59 | 6818 |
| MANBA | 6817 |
| FBXO15 | 6797 |
| SMARCA4 | 6773 |
| DOCK1 | 6760 |
| EDA2R | 6745 |
| SLC11A1 | 6739 |
| UBE2D1 | 6734 |
| GBP1 | 6692 |
| IRS1 | 6691 |
| C5AR2 | 6671 |
| BIRC3 | 6654 |
| IRF4 | 6647 |
| HEBP2 | 6631 |
| ZNRF2 | 6602 |
| PPL | 6600 |
| UBE2L3 | 6589 |
| PA2G4 | 6585 |
| HERC3 | 6583 |
| ENAH | 6582 |
| SEM1 | 6566 |
| RAB5C | 6565 |
| LNPEP | 6564 |
| FN1 | 6525 |
| TRIM50 | 6504 |
| APRT | 6499 |
| PDZD11 | 6494 |
| DBNL | 6490 |
| STUB1 | 6475 |
| UBE2V2 | 6467 |
| TMEM63A | 6449 |
| IL4R | 6431 |
| KLHL20 | 6424 |
| PSMA3 | 6422 |
| RAP1GAP2 | 6395 |
| NUP54 | 6371 |
| SUMO1 | 6365 |
| CUL3 | 6363 |
| CPNE3 | 6354 |
| KIF3A | 6347 |
| GRB2 | 6346 |
| LYN | 6328 |
| TRIM35 | 6318 |
| RPS6KA3 | 6316 |
| IFITM2 | 6308 |
| LAIR1 | 6304 |
| ABL2 | 6296 |
| CTNNB1 | 6288 |
| ELOB | 6272 |
| TXLNA | 6268 |
| SLC2A5 | 6243 |
| SAR1B | 6198 |
| WIPF2 | 6174 |
| APOB | 6172 |
| PLAU | 6169 |
| AKT1 | 6160 |
| TMEM30A | 6157 |
| UBE2D4 | 6143 |
| RCHY1 | 6131 |
| RAB4B | 6116 |
| JUN | 6103 |
| IKBKB | 6100 |
| PSMD8 | 6091 |
| CASP8 | 6085 |
| POLR3K | 6076 |
| AP2S1 | 6073 |
| CBLB | 6025 |
| PDCD4 | 6023 |
| RBCK1 | 6012 |
| RIPK1 | 6000 |
| FBXL22 | 5990 |
| KLC3 | 5986 |
| TRAPPC1 | 5956 |
| RPS6KA5 | 5949 |
| PIN1 | 5922 |
| STK11IP | 5898 |
| DTX4 | 5869 |
| CD99 | 5861 |
| PIK3CA | 5849 |
| GRN | 5836 |
| ASB3 | 5827 |
| ARPC1A | 5822 |
| TOMM70 | 5819 |
| RAB27A | 5804 |
| NCKAP1 | 5794 |
| VAMP7 | 5793 |
| DYNC1I2 | 5783 |
| ELMO1 | 5782 |
| RPS27A | 5776 |
| EEA1 | 5759 |
| RHOG | 5747 |
| AAAS | 5701 |
| MAPK10 | 5681 |
| JAK2 | 5664 |
| KBTBD8 | 5662 |
| SEC23A | 5659 |
| PSMA5 | 5657 |
| ATG5 | 5644 |
| AP1M1 | 5637 |
| FBXL8 | 5631 |
| RAB5B | 5611 |
| HERC1 | 5582 |
| EIF2AK2 | 5562 |
| ARSA | 5552 |
| ADAM10 | 5549 |
| BST2 | 5531 |
| FLNB | 5530 |
| UBE2E3 | 5512 |
| S100P | 5511 |
| RNF34 | 5503 |
| RNF115 | 5494 |
| RELA | 5468 |
| LAMTOR3 | 5467 |
| IRF5 | 5450 |
| FBXL14 | 5439 |
| VAV2 | 5425 |
| CTSD | 5416 |
| MID1 | 5413 |
| NUP43 | 5410 |
| RHOF | 5403 |
| PIK3CB | 5379 |
| UBE2B | 5375 |
| PSMD13 | 5353 |
| PAG1 | 5350 |
| MAP3K14 | 5349 |
| HLA-B | 5329 |
| FBXW7 | 5325 |
| PPP2R5C | 5293 |
| TNFRSF14 | 5289 |
| UBE3A | 5286 |
| FBXW10 | 5268 |
| B2M | 5242 |
| DYNC1LI1 | 5237 |
| NUP153 | 5230 |
| FUCA1 | 5210 |
| POLR3H | 5168 |
| CPPED1 | 5138 |
| PJA1 | 5131 |
| UFL1 | 5128 |
| SERPINB6 | 5125 |
| UBE2Q2 | 5107 |
| SP100 | 5083 |
| WASF3 | 5070 |
| ATP11B | 5015 |
| QPCT | 5009 |
| FSCN1 | 5006 |
| CANT1 | 4969 |
| TAB3 | 4960 |
| PSMC2 | 4948 |
| STX1A | 4922 |
| GBP5 | 4914 |
| TLR9 | 4913 |
| PLAC8 | 4886 |
| MAP2K6 | 4868 |
| PSME1 | 4861 |
| PLCG1 | 4855 |
| DYNLL1 | 4853 |
| HTN3 | 4834 |
| IFNAR2 | 4798 |
| PRKDC | 4777 |
| EIF4E | 4766 |
| MEFV | 4758 |
| EVL | 4757 |
| PIK3R3 | 4734 |
| PRCP | 4730 |
| POLR3B | 4721 |
| RNF111 | 4714 |
| UBOX5 | 4712 |
| UBA6 | 4704 |
| UBR1 | 4691 |
| SLC15A4 | 4647 |
| NECTIN2 | 4645 |
| PTPN4 | 4643 |
| ARMC8 | 4638 |
| SPTAN1 | 4610 |
| NUP58 | 4603 |
| IRAK1 | 4593 |
| C8G | 4585 |
| ARPC2 | 4575 |
| CARD9 | 4496 |
| CDC42 | 4489 |
| ARHGAP9 | 4486 |
| JUP | 4478 |
| MGST1 | 4472 |
| NRAS | 4465 |
| EIF4E3 | 4457 |
| FOXO3 | 4415 |
| GSTO1 | 4401 |
| KLRG1 | 4392 |
| MAPK14 | 4391 |
| PPP2R5D | 4385 |
| KIF5C | 4382 |
| FBXL19 | 4369 |
| ITPR2 | 4366 |
| PRR5 | 4323 |
| CYBA | 4283 |
| RICTOR | 4274 |
| CRISPLD2 | 4273 |
| KLRK1 | 4247 |
| SERPINB1 | 4239 |
| SVIP | 4238 |
| AGER | 4235 |
| AGL | 4233 |
| POLR3A | 4231 |
| KRAS | 4210 |
| CTSV | 4202 |
| SDC1 | 4201 |
| KLRD1 | 4192 |
| HECTD3 | 4185 |
| IFNLR1 | 4179 |
| CAMK2G | 4176 |
| FBXL3 | 4168 |
| GDI2 | 4162 |
| TP53 | 4144 |
| UBE2E2 | 4127 |
| ATP7A | 4123 |
| IST1 | 4111 |
| IL18 | 4103 |
| YWHAB | 4062 |
| ANAPC13 | 4052 |
| UBE2W | 4047 |
| TICAM1 | 4022 |
| AKT2 | 3993 |
| DCTN4 | 3979 |
| NUP214 | 3957 |
| AP2B1 | 3955 |
| ABL1 | 3944 |
| AP1G1 | 3931 |
| PSMB3 | 3928 |
| AP2A1 | 3903 |
| ANAPC1 | 3900 |
| LRRC41 | 3889 |
| TNFSF14 | 3876 |
| PTPRN2 | 3851 |
| MAPK13 | 3846 |
| UBE2S | 3839 |
| IL6ST | 3837 |
| UNC13D | 3835 |
| PELI2 | 3834 |
| RNF138 | 3815 |
| CYFIP1 | 3785 |
| FYN | 3783 |
| FBXO9 | 3776 |
| PDE12 | 3769 |
| BCL2 | 3762 |
| ITGAX | 3756 |
| SDCBP | 3724 |
| MYC | 3708 |
| FADD | 3704 |
| LTN1 | 3702 |
| IMPDH1 | 3690 |
| CLEC7A | 3685 |
| PSMB2 | 3678 |
| MLST8 | 3677 |
| HERC5 | 3641 |
| KIF3C | 3639 |
| GLMN | 3608 |
| UBE2N | 3604 |
| HSPA1A | 3603 |
| PILRA | 3588 |
| SCAMP1 | 3566 |
| BTNL9 | 3539 |
| POLR3C | 3531 |
| LTBR | 3510 |
| NPEPPS | 3480 |
| KPNA4 | 3478 |
| MAPK9 | 3449 |
| TRIM71 | 3441 |
| MMP3 | 3425 |
| PRKACA | 3407 |
| CAND1 | 3381 |
| CAMK2D | 3358 |
| ANAPC2 | 3349 |
| DCTN1 | 3338 |
| MAVS | 3323 |
| HTN1 | 3309 |
| HAVCR2 | 3267 |
| SUGT1 | 3265 |
| RAB10 | 3205 |
| IFNGR1 | 3204 |
| RAB3D | 3155 |
| TRAF6 | 3150 |
| CAPZA2 | 3143 |
| IRAK4 | 3137 |
| ANAPC11 | 3134 |
| STAT6 | 3128 |
| SLC2A3 | 3116 |
| CDC27 | 3103 |
| MUC13 | 3097 |
| STOM | 3093 |
| LIMK1 | 3082 |
| USP41 | 3076 |
| ARIH1 | 3075 |
| ARPC5 | 3073 |
| PSMC3 | 3070 |
| FBXL18 | 3067 |
| GLB1 | 3064 |
| POLR3G | 3049 |
| LGALS9 | 3034 |
| NDC1 | 3023 |
| NCK1 | 3010 |
| EGR1 | 2989 |
| SIGIRR | 2961 |
| CTSS | 2960 |
| MX2 | 2953 |
| GSN | 2952 |
| ATP11A | 2935 |
| CXCR2 | 2899 |
| DCTN3 | 2887 |
| PRKACB | 2885 |
| RNF217 | 2873 |
| IL23A | 2869 |
| IL17RC | 2861 |
| ACTR2 | 2855 |
| ORAI1 | 2851 |
| UBE4A | 2850 |
| ADGRG3 | 2825 |
| SEC61A2 | 2808 |
| UBR2 | 2800 |
| BTRC | 2757 |
| PIK3R2 | 2728 |
| SOCS2 | 2710 |
| NUP133 | 2708 |
| MICA | 2693 |
| YES1 | 2690 |
| LY96 | 2689 |
| MOSPD2 | 2673 |
| GBP4 | 2652 |
| PPIE | 2651 |
| TNIP2 | 2640 |
| NFKB2 | 2634 |
| SPSB2 | 2622 |
| EDA | 2594 |
| RAB6A | 2578 |
| VRK3 | 2573 |
| CCNF | 2569 |
| UBA3 | 2562 |
| ICAM1 | 2548 |
| BRWD1 | 2546 |
| HERC4 | 2535 |
| APAF1 | 2532 |
| QSOX1 | 2518 |
| POU2F1 | 2513 |
| LMO7 | 2512 |
| ATP6AP2 | 2508 |
| ORM2 | 2502 |
| GUSB | 2493 |
| CUL5 | 2485 |
| KLHL11 | 2475 |
| MYO1C | 2457 |
| PLD3 | 2446 |
| ABI2 | 2431 |
| OPRD1 | 2430 |
| ADAM8 | 2424 |
| MGRN1 | 2418 |
| HECTD2 | 2378 |
| CAPZB | 2376 |
| GYG1 | 2373 |
| ERAP1 | 2345 |
| RPS6KA2 | 2339 |
| PSMB4 | 2330 |
| FBXL12 | 2320 |
| CIITA | 2310 |
| CDC16 | 2309 |
| TRIM38 | 2306 |
| NANOG | 2288 |
| MT2A | 2284 |
| CD74 | 2282 |
| EIF4A3 | 2270 |
| ITK | 2265 |
| RAP2C | 2257 |
| ASB8 | 2243 |
| BOLA2 | 2230 |
| PIK3R4 | 2219 |
| TLR6 | 2218 |
| SIRPB1 | 2169 |
| PECAM1 | 2152 |
| JAML | 2138 |
| SPSB1 | 2118 |
| TNFSF13 | 2105 |
| OSBPL1A | 2101 |
| HSP90AA1 | 2096 |
| MUC20 | 2082 |
| IFI27 | 2080 |
| PSMB1 | 2062 |
| PML | 2057 |
| KLHL5 | 2025 |
| PAK1 | 2021 |
| NCKAP1L | 1980 |
| RLIM | 1979 |
| LGMN | 1966 |
| RNF220 | 1964 |
| IFNGR2 | 1962 |
| UBE2Z | 1959 |
| RNF114 | 1958 |
| NAPRT | 1945 |
| CRCP | 1930 |
| SOS1 | 1928 |
| PCBP2 | 1919 |
| HNRNPDL | 1890 |
| CD79A | 1885 |
| DDX58 | 1883 |
| CD40 | 1869 |
| MICB | 1866 |
| FBXO7 | 1865 |
| SH3KBP1 | 1864 |
| UBE2D2 | 1857 |
| ELMO2 | 1854 |
| AP1B1 | 1849 |
| LCP1 | 1834 |
| PSMA7 | 1820 |
| YWHAZ | 1810 |
| NFKBIE | 1799 |
| COTL1 | 1794 |
| AP1M2 | 1788 |
| FBXL13 | 1783 |
| ATP6V1F | 1771 |
| PTPN11 | 1770 |
| IL1R2 | 1751 |
| FBXW9 | 1747 |
| IRF3 | 1694 |
| SEC22B | 1690 |
| AMPD3 | 1688 |
| GHDC | 1682 |
| ABCE1 | 1665 |
| SLC27A2 | 1635 |
| IKBKE | 1593 |
| CDKN1B | 1590 |
| WWP1 | 1572 |
| LAMTOR1 | 1557 |
| UBC | 1551 |
| CSTB | 1547 |
| TNFSF9 | 1527 |
| ATP6V0D2 | 1494 |
| PSMB5 | 1484 |
| AP1S3 | 1480 |
| STXBP2 | 1474 |
| GHR | 1455 |
| UBE2G2 | 1451 |
| ICAM5 | 1440 |
| SNAP29 | 1422 |
| RNASET2 | 1419 |
| MAPK8 | 1418 |
| VAMP3 | 1415 |
| BST1 | 1408 |
| NOS1 | 1403 |
| DNAJC13 | 1370 |
| ATP6V1G2 | 1360 |
| POLR3F | 1355 |
| CALM1 | 1340 |
| KCNAB2 | 1323 |
| LAT2 | 1316 |
| TNFRSF9 | 1299 |
| BAIAP2 | 1295 |
| ELOC | 1265 |
| IL22RA1 | 1251 |
| RNF7 | 1249 |
| F2 | 1246 |
| ASB18 | 1231 |
| MAN2B1 | 1230 |
| SIGLEC10 | 1218 |
| RNF25 | 1216 |
| FBXL15 | 1200 |
| INPPL1 | 1197 |
| TRAF2 | 1180 |
| FRK | 1179 |
| CYB5R3 | 1177 |
| RASGRP3 | 1164 |
| DHX36 | 1159 |
| ZNRF1 | 1153 |
| IL15 | 1148 |
| TAP2 | 1143 |
| CCL22 | 1142 |
| NCSTN | 1137 |
| SKP1 | 1117 |
| IFITM1 | 1106 |
| TPR | 1105 |
| ATP6V1E2 | 1090 |
| ZEB1 | 1087 |
| UNC93B1 | 1053 |
| CRKL | 1039 |
| COLEC12 | 1036 |
| UBA1 | 1021 |
| BIRC2 | 1007 |
| LRR1 | 1000 |
| STX4 | 995 |
| CD19 | 954 |
| PAFAH1B2 | 953 |
| RELB | 951 |
| CREB1 | 935 |
| PSMD11 | 879 |
| RAPGEF4 | 863 |
| PSMB10 | 838 |
| TAP1 | 836 |
| TRIM29 | 834 |
| IL12RB1 | 832 |
| UBE2R2 | 790 |
| PDPK1 | 782 |
| RNF4 | 771 |
| RAB18 | 760 |
| UBE2K | 750 |
| PPP3CA | 748 |
| FCER1G | 746 |
| TNFSF15 | 730 |
| TRAF3 | 729 |
| CD226 | 728 |
| CUL2 | 703 |
| IRF2 | 690 |
| NUP160 | 683 |
| DCTN6 | 666 |
| IL1RL1 | 665 |
| ADGRE5 | 651 |
| UBAC1 | 648 |
| STK10 | 642 |
| AREL1 | 629 |
| NUP62 | 618 |
| RAP1A | 604 |
| FBXW2 | 602 |
| ANAPC4 | 595 |
| TNFRSF25 | 581 |
| PIAS1 | 560 |
| PPP2R5E | 554 |
| B4GALT1 | 540 |
| CMTM6 | 535 |
| IL16 | 518 |
| PGM2 | 513 |
| KPNA5 | 506 |
| PGRMC1 | 498 |
| MAPK11 | 492 |
| GMFG | 450 |
| KLHL25 | 441 |
| CDC26 | 402 |
| FZR1 | 397 |
| NEDD4 | 383 |
| IL17RA | 382 |
| CASP4 | 379 |
| KCTD6 | 368 |
| TRIM46 | 353 |
| TCIRG1 | 348 |
| REL | 330 |
| ICAM4 | 315 |
| LAMTOR2 | 299 |
| NKIRAS1 | 298 |
| CCND1 | 277 |
| PILRB | 276 |
| FBXO30 | 270 |
| NLRP1 | 269 |
| TAPBP | 266 |
| PSMA6 | 261 |
| RNF135 | 247 |
| CTSE | 246 |
| IL27RA | 242 |
| DGAT1 | 222 |
| CPN2 | 221 |
| FBXO2 | 158 |
| CRACR2A | 155 |
| STAT2 | 146 |
| CXADR | 136 |
| PRDX6 | 106 |
| RAC1 | 95 |
| CSF2RA | 94 |
| CREG1 | 87 |
| BTBD1 | 81 |
| XRCC6 | 67 |
| AHSG | 62 |
| FBXO10 | 43 |
| RANBP2 | 9 |
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
| 954 | |
|---|---|
| set | Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| setSize | 99 |
| pANOVA | 5.59e-07 |
| s.dist | 0.291 |
| p.adjustANOVA | 7e-05 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| DNAJC3 | 14516 |
| HSP90B1 | 14514 |
| KNG1 | 14503 |
| PCSK9 | 14502 |
| PLG | 14495 |
| PDIA6 | 14482 |
| IGF2 | 14477 |
| WFS1 | 14466 |
| C3 | 14417 |
| MIA3 | 14404 |
| C4A | 14381 |
| FGA | 14346 |
| FAM20A | 14315 |
| CP | 14292 |
| MATN3 | 14207 |
| MELTF | 14199 |
| P4HB | 14170 |
| BMP4 | 14148 |
| VGF | 14140 |
| CSF1 | 13888 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| DNAJC3 | 14516 |
| HSP90B1 | 14514 |
| KNG1 | 14503 |
| PCSK9 | 14502 |
| PLG | 14495 |
| PDIA6 | 14482 |
| IGF2 | 14477 |
| WFS1 | 14466 |
| C3 | 14417 |
| MIA3 | 14404 |
| C4A | 14381 |
| FGA | 14346 |
| FAM20A | 14315 |
| CP | 14292 |
| MATN3 | 14207 |
| MELTF | 14199 |
| P4HB | 14170 |
| BMP4 | 14148 |
| VGF | 14140 |
| CSF1 | 13888 |
| FBN1 | 13813 |
| LGALS1 | 13778 |
| SERPINC1 | 13683 |
| FUCA2 | 13600 |
| APP | 13532 |
| APOA1 | 13433 |
| APOA2 | 13191 |
| TIMP1 | 13158 |
| STC2 | 13029 |
| NOTUM | 12998 |
| PROC | 12863 |
| FGG | 12809 |
| SERPIND1 | 12796 |
| MBTPS1 | 12523 |
| PRKCSH | 12463 |
| SPP1 | 12355 |
| IGFBP2 | 12133 |
| VCAN | 11899 |
| IGFBP3 | 11532 |
| HRC | 11335 |
| PNPLA2 | 11306 |
| IGFALS | 11119 |
| TF | 11111 |
| FSTL3 | 11092 |
| NUCB1 | 10770 |
| MGAT4A | 10584 |
| MFGE8 | 10560 |
| BPIFB2 | 10473 |
| GOLM1 | 10136 |
| EVA1A | 9995 |
| MMP2 | 9932 |
| CALU | 9602 |
| IGFBP4 | 9571 |
| FAM20C | 9378 |
| APOL1 | 9284 |
| SHISA5 | 9203 |
| AFP | 8777 |
| MSLN | 8649 |
| MXRA8 | 8582 |
| CKAP4 | 8327 |
| IGFBP1 | 8301 |
| IGFBP7 | 8108 |
| SERPINA10 | 7992 |
| GPC3 | 7971 |
| APOA5 | 7816 |
| APOE | 7759 |
| SERPINA1 | 7622 |
| LAMB1 | 7198 |
| CST3 | 7101 |
| APLP2 | 7009 |
| KTN1 | 6769 |
| RCN1 | 6562 |
| FN1 | 6525 |
| APOB | 6172 |
| ALB | 5965 |
| IGFBP6 | 5787 |
| ADAM10 | 5549 |
| VWA1 | 5457 |
| CYR61 | 5367 |
| GAS6 | 5226 |
| CDH2 | 4845 |
| TMEM132A | 4597 |
| TGOLN2 | 4352 |
| CHGB | 4319 |
| FGF23 | 4091 |
| LTBP1 | 3905 |
| ITIH2 | 3417 |
| SPP2 | 3138 |
| PAPPA | 2849 |
| LAMC1 | 2611 |
| MEN1 | 2581 |
| QSOX1 | 2518 |
| F5 | 1638 |
| PRSS23 | 1288 |
| F2 | 1246 |
| LAMB2 | 978 |
| ANO8 | 350 |
| SDC2 | 289 |
| AHSG | 62 |
Complement cascade
| 187 | |
|---|---|
| set | Complement cascade |
| setSize | 35 |
| pANOVA | 6.84e-07 |
| s.dist | 0.485 |
| p.adjustANOVA | 7.85e-05 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SERPING1 | 14532 |
| C1S | 14430 |
| C3 | 14417 |
| CFB | 14394 |
| C4A | 14381 |
| C8B | 14372 |
| C4B | 14173 |
| C8A | 14042 |
| C4BPB | 14006 |
| C5 | 14003 |
| C1R | 13954 |
| CD55 | 13575 |
| MBL2 | 13247 |
| VTN | 13246 |
| CFI | 13206 |
| C5AR1 | 12862 |
| MASP1 | 12716 |
| C6 | 12636 |
| COLEC11 | 12595 |
| PROS1 | 11519 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SERPING1 | 14532 |
| C1S | 14430 |
| C3 | 14417 |
| CFB | 14394 |
| C4A | 14381 |
| C8B | 14372 |
| C4B | 14173 |
| C8A | 14042 |
| C4BPB | 14006 |
| C5 | 14003 |
| C1R | 13954 |
| CD55 | 13575 |
| MBL2 | 13247 |
| VTN | 13246 |
| CFI | 13206 |
| C5AR1 | 12862 |
| MASP1 | 12716 |
| C6 | 12636 |
| COLEC11 | 12595 |
| PROS1 | 11519 |
| MASP2 | 10923 |
| CLU | 10723 |
| CFD | 10570 |
| C4BPA | 9865 |
| CD46 | 9531 |
| C7 | 9004 |
| CPB2 | 8234 |
| C2 | 8098 |
| CPN1 | 7658 |
| CD59 | 6818 |
| C5AR2 | 6671 |
| C8G | 4585 |
| F2 | 1246 |
| CD19 | 954 |
| CPN2 | 221 |
Post-translational protein phosphorylation
| 815 | |
|---|---|
| set | Post-translational protein phosphorylation |
| setSize | 91 |
| pANOVA | 1.12e-06 |
| s.dist | 0.296 |
| p.adjustANOVA | 0.000118 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| DNAJC3 | 14516 |
| HSP90B1 | 14514 |
| KNG1 | 14503 |
| PCSK9 | 14502 |
| PDIA6 | 14482 |
| WFS1 | 14466 |
| C3 | 14417 |
| MIA3 | 14404 |
| C4A | 14381 |
| FGA | 14346 |
| FAM20A | 14315 |
| CP | 14292 |
| MATN3 | 14207 |
| MELTF | 14199 |
| P4HB | 14170 |
| BMP4 | 14148 |
| VGF | 14140 |
| CSF1 | 13888 |
| FBN1 | 13813 |
| LGALS1 | 13778 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| DNAJC3 | 14516 |
| HSP90B1 | 14514 |
| KNG1 | 14503 |
| PCSK9 | 14502 |
| PDIA6 | 14482 |
| WFS1 | 14466 |
| C3 | 14417 |
| MIA3 | 14404 |
| C4A | 14381 |
| FGA | 14346 |
| FAM20A | 14315 |
| CP | 14292 |
| MATN3 | 14207 |
| MELTF | 14199 |
| P4HB | 14170 |
| BMP4 | 14148 |
| VGF | 14140 |
| CSF1 | 13888 |
| FBN1 | 13813 |
| LGALS1 | 13778 |
| SERPINC1 | 13683 |
| FUCA2 | 13600 |
| APP | 13532 |
| APOA1 | 13433 |
| APOA2 | 13191 |
| TIMP1 | 13158 |
| STC2 | 13029 |
| NOTUM | 12998 |
| PROC | 12863 |
| FGG | 12809 |
| SERPIND1 | 12796 |
| MBTPS1 | 12523 |
| PRKCSH | 12463 |
| SPP1 | 12355 |
| VCAN | 11899 |
| IGFBP3 | 11532 |
| HRC | 11335 |
| PNPLA2 | 11306 |
| TF | 11111 |
| FSTL3 | 11092 |
| NUCB1 | 10770 |
| MGAT4A | 10584 |
| MFGE8 | 10560 |
| BPIFB2 | 10473 |
| GOLM1 | 10136 |
| EVA1A | 9995 |
| CALU | 9602 |
| IGFBP4 | 9571 |
| FAM20C | 9378 |
| APOL1 | 9284 |
| SHISA5 | 9203 |
| AFP | 8777 |
| MSLN | 8649 |
| MXRA8 | 8582 |
| CKAP4 | 8327 |
| IGFBP1 | 8301 |
| IGFBP7 | 8108 |
| SERPINA10 | 7992 |
| GPC3 | 7971 |
| APOA5 | 7816 |
| APOE | 7759 |
| SERPINA1 | 7622 |
| LAMB1 | 7198 |
| CST3 | 7101 |
| APLP2 | 7009 |
| KTN1 | 6769 |
| RCN1 | 6562 |
| FN1 | 6525 |
| APOB | 6172 |
| ALB | 5965 |
| ADAM10 | 5549 |
| VWA1 | 5457 |
| CYR61 | 5367 |
| GAS6 | 5226 |
| CDH2 | 4845 |
| TMEM132A | 4597 |
| TGOLN2 | 4352 |
| CHGB | 4319 |
| FGF23 | 4091 |
| LTBP1 | 3905 |
| ITIH2 | 3417 |
| SPP2 | 3138 |
| LAMC1 | 2611 |
| MEN1 | 2581 |
| QSOX1 | 2518 |
| F5 | 1638 |
| PRSS23 | 1288 |
| LAMB2 | 978 |
| ANO8 | 350 |
| SDC2 | 289 |
| AHSG | 62 |
Post-translational protein modification
| 814 | |
|---|---|
| set | Post-translational protein modification |
| setSize | 1138 |
| pANOVA | 4.03e-06 |
| s.dist | 0.0822 |
| p.adjustANOVA | 0.000396 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CALR | 14529 |
| RAB17 | 14521 |
| SEC24D | 14520 |
| DNAJC3 | 14516 |
| HSP90B1 | 14514 |
| SEL1L | 14508 |
| KNG1 | 14503 |
| PCSK9 | 14502 |
| SELENOS | 14498 |
| MUC5B | 14487 |
| SYVN1 | 14485 |
| PDIA6 | 14482 |
| EDEM1 | 14479 |
| SOCS3 | 14476 |
| WFS1 | 14466 |
| CANX | 14462 |
| PDIA3 | 14454 |
| SLC17A5 | 14434 |
| TMED2 | 14433 |
| KLHL21 | 14429 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CALR | 14529 |
| RAB17 | 14521 |
| SEC24D | 14520 |
| DNAJC3 | 14516 |
| HSP90B1 | 14514 |
| SEL1L | 14508 |
| KNG1 | 14503 |
| PCSK9 | 14502 |
| SELENOS | 14498 |
| MUC5B | 14487 |
| SYVN1 | 14485 |
| PDIA6 | 14482 |
| EDEM1 | 14479 |
| SOCS3 | 14476 |
| WFS1 | 14466 |
| CANX | 14462 |
| PDIA3 | 14454 |
| SLC17A5 | 14434 |
| TMED2 | 14433 |
| KLHL21 | 14429 |
| MCFD2 | 14425 |
| ARRB1 | 14420 |
| C3 | 14417 |
| GCNT3 | 14407 |
| GFPT1 | 14406 |
| MIA3 | 14404 |
| DERL2 | 14399 |
| MAGT1 | 14398 |
| C4A | 14381 |
| WSB2 | 14373 |
| ARSG | 14366 |
| RPN1 | 14350 |
| FGA | 14346 |
| FUT3 | 14335 |
| OS9 | 14320 |
| FAM20A | 14315 |
| CP | 14292 |
| ASB2 | 14280 |
| UGGT1 | 14270 |
| ARSB | 14246 |
| TGFB1 | 14241 |
| TMED7 | 14240 |
| MVD | 14220 |
| MATN3 | 14207 |
| NANS | 14204 |
| MELTF | 14199 |
| MLEC | 14193 |
| P4HB | 14170 |
| BMP4 | 14148 |
| VGF | 14140 |
| FBXL16 | 14129 |
| GMPPB | 14096 |
| SEC24A | 14088 |
| TRAPPC6A | 14069 |
| SEC13 | 14049 |
| ST3GAL4 | 14033 |
| CDK1 | 14027 |
| STT3A | 14026 |
| CBX5 | 14012 |
| POMT2 | 14007 |
| ANK2 | 13993 |
| TMEM115 | 13976 |
| NEU1 | 13953 |
| MBD6 | 13936 |
| ST6GALNAC4 | 13912 |
| PPARA | 13906 |
| VCP | 13902 |
| CSF1 | 13888 |
| RAB43 | 13874 |
| FURIN | 13851 |
| SLC35C1 | 13821 |
| SIAH2 | 13819 |
| DDX5 | 13814 |
| FBN1 | 13813 |
| PSMF1 | 13810 |
| RAD23A | 13802 |
| UBE2C | 13793 |
| LGALS1 | 13778 |
| RECK | 13774 |
| GALNT11 | 13771 |
| SOCS5 | 13766 |
| RNF5 | 13745 |
| UIMC1 | 13741 |
| RAB20 | 13727 |
| TTLL3 | 13715 |
| NUP37 | 13706 |
| ALG3 | 13700 |
| SERPINC1 | 13683 |
| TUBA1B | 13681 |
| TRAPPC10 | 13677 |
| FOXK2 | 13656 |
| NEU3 | 13653 |
| LMAN2 | 13641 |
| ALG2 | 13631 |
| USP16 | 13615 |
| FUCA2 | 13600 |
| COPB2 | 13594 |
| RAB22A | 13585 |
| CD55 | 13575 |
| PPP6R1 | 13558 |
| ARCN1 | 13549 |
| TMED9 | 13545 |
| ADAMTSL4 | 13538 |
| APP | 13532 |
| VHL | 13531 |
| KEAP1 | 13510 |
| TOP1 | 13490 |
| ALG5 | 13488 |
| EP300 | 13485 |
| CLSPN | 13484 |
| MAN1A2 | 13466 |
| PSME4 | 13450 |
| APOA1 | 13433 |
| NFKBIA | 13427 |
| RAB37 | 13426 |
| PSMD2 | 13423 |
| DDOST | 13410 |
| DERL1 | 13398 |
| ADAMTS10 | 13383 |
| SPON2 | 13375 |
| MGAT1 | 13371 |
| NUS1 | 13362 |
| CBX2 | 13350 |
| DNMT3B | 13348 |
| NEU4 | 13335 |
| ADAMTS2 | 13309 |
| RNF185 | 13291 |
| THSD4 | 13286 |
| POM121 | 13281 |
| GMPPA | 13267 |
| CHST10 | 13262 |
| APOA2 | 13191 |
| AURKB | 13190 |
| TOP2A | 13176 |
| TIMP1 | 13158 |
| CTSA | 13149 |
| MGAT4B | 13132 |
| B4GALT5 | 13121 |
| RARA | 13109 |
| DAD1 | 13053 |
| SEC24C | 13047 |
| TTLL11 | 13041 |
| UBE2J2 | 13040 |
| STC2 | 13029 |
| NUP210 | 13025 |
| KBTBD6 | 13016 |
| TECTB | 13015 |
| NOTUM | 12998 |
| TBC1D20 | 12985 |
| CUL9 | 12968 |
| KBTBD7 | 12967 |
| RPN2 | 12964 |
| HLTF | 12961 |
| PIGG | 12950 |
| SAFB | 12947 |
| TUBA1C | 12940 |
| TUBB4B | 12934 |
| DDB2 | 12925 |
| COG8 | 12910 |
| SEC16B | 12908 |
| DPH5 | 12882 |
| SMAD3 | 12871 |
| TTLL1 | 12868 |
| PROC | 12863 |
| DCAF11 | 12860 |
| YOD1 | 12859 |
| RNF103 | 12848 |
| TMED10 | 12817 |
| FGG | 12809 |
| SERPIND1 | 12796 |
| TAB1 | 12789 |
| ART4 | 12770 |
| NSMCE1 | 12769 |
| ALG12 | 12752 |
| CYLD | 12727 |
| SCMH1 | 12722 |
| HCFC1 | 12714 |
| CDCA8 | 12700 |
| IFIH1 | 12693 |
| RWDD3 | 12691 |
| DPAGT1 | 12688 |
| POM121C | 12687 |
| NR1H4 | 12674 |
| ARF1 | 12642 |
| RAB9A | 12633 |
| JOSD1 | 12588 |
| CCNA2 | 12587 |
| GALNT2 | 12555 |
| SEC16A | 12546 |
| WAC | 12537 |
| COPE | 12527 |
| MBTPS1 | 12523 |
| ALG11 | 12520 |
| PSMD6 | 12502 |
| COG3 | 12497 |
| IKBKG | 12493 |
| FBXW5 | 12489 |
| OTUD5 | 12487 |
| PRKCSH | 12463 |
| PCNA | 12452 |
| NAPA | 12433 |
| ST3GAL1 | 12408 |
| ADAMTS6 | 12405 |
| ZRANB1 | 12391 |
| KDELR2 | 12387 |
| MUL1 | 12386 |
| UBE2F | 12374 |
| SIN3A | 12373 |
| PCGF2 | 12369 |
| RORA | 12360 |
| SPP1 | 12355 |
| PPARGC1A | 12350 |
| MGAT5 | 12324 |
| ENGASE | 12309 |
| OGT | 12301 |
| ASXL2 | 12292 |
| FN3KRP | 12265 |
| DCUN1D3 | 12244 |
| ARF4 | 12225 |
| RAB7A | 12220 |
| ADAMTS9 | 12207 |
| PSMA2 | 12203 |
| ASB13 | 12175 |
| RIPK2 | 12158 |
| SEC31A | 12138 |
| UBE2G1 | 12134 |
| RENBP | 12130 |
| AXIN2 | 12097 |
| USP30 | 12091 |
| VNN3 | 12074 |
| F7 | 12069 |
| PSMA1 | 12052 |
| CSNK1D | 12038 |
| HIPK2 | 11978 |
| DDB1 | 11967 |
| EIF5A | 11952 |
| VCAN | 11899 |
| FKBP8 | 11886 |
| DDA1 | 11862 |
| DPH2 | 11858 |
| PIGK | 11827 |
| PROZ | 11823 |
| CCP110 | 11807 |
| RAD52 | 11769 |
| SUMF1 | 11754 |
| PSMC1 | 11724 |
| SHPRH | 11706 |
| COPG2 | 11691 |
| BARD1 | 11687 |
| FBXO41 | 11685 |
| SENP8 | 11684 |
| NR5A2 | 11680 |
| PSMD3 | 11655 |
| ARSI | 11653 |
| EDEM2 | 11628 |
| TAF9B | 11625 |
| CDC34 | 11619 |
| TRIM25 | 11574 |
| FBXO31 | 11563 |
| NUP107 | 11561 |
| PSME2 | 11555 |
| SEC24B | 11541 |
| IGFBP3 | 11532 |
| SOCS6 | 11523 |
| USP13 | 11521 |
| PROS1 | 11519 |
| GNE | 11517 |
| RAD18 | 11508 |
| DYNLL2 | 11507 |
| XPNPEP2 | 11506 |
| FBXW4 | 11502 |
| RNF40 | 11493 |
| UBXN1 | 11466 |
| CISH | 11440 |
| USP2 | 11427 |
| BLM | 11423 |
| B3GLCT | 11411 |
| DCAF10 | 11410 |
| THBS1 | 11408 |
| FBXO17 | 11405 |
| PTRH2 | 11393 |
| RAB5A | 11392 |
| NUP35 | 11387 |
| DPH1 | 11373 |
| PSMD14 | 11371 |
| PGM3 | 11367 |
| HRC | 11335 |
| CDC25A | 11334 |
| PGAP1 | 11332 |
| RAB2A | 11326 |
| SKP2 | 11323 |
| VASH2 | 11320 |
| PNPLA2 | 11306 |
| PSMD1 | 11280 |
| ST3GAL3 | 11257 |
| OTUB2 | 11254 |
| TFG | 11250 |
| THSD1 | 11244 |
| ALG10B | 11213 |
| GOLGA2 | 11209 |
| STX5 | 11191 |
| FBXO32 | 11189 |
| RHOA | 11182 |
| PUM2 | 11167 |
| RAB32 | 11166 |
| USP18 | 11159 |
| STAMBP | 11154 |
| PIGW | 11146 |
| NUP205 | 11144 |
| RAB35 | 11131 |
| USP22 | 11124 |
| TF | 11111 |
| PIGL | 11096 |
| SMURF2 | 11093 |
| FSTL3 | 11092 |
| TPGS1 | 11091 |
| RNF20 | 11085 |
| ASB6 | 11077 |
| PPP6C | 11074 |
| NUP93 | 11067 |
| UCHL3 | 11055 |
| AGTPBP1 | 11045 |
| CETN2 | 11018 |
| YY1 | 11015 |
| RABGGTB | 10986 |
| HLA-A | 10971 |
| PMM2 | 10956 |
| TADA2B | 10948 |
| SENP5 | 10920 |
| ACTR1A | 10903 |
| COPS2 | 10902 |
| NAE1 | 10901 |
| F10 | 10888 |
| CMAS | 10871 |
| UBE2T | 10846 |
| PRMT3 | 10843 |
| COPG1 | 10840 |
| FUT8 | 10839 |
| USP42 | 10780 |
| FBXL5 | 10775 |
| COMMD6 | 10773 |
| NUCB1 | 10770 |
| KDELR1 | 10752 |
| NR1I2 | 10746 |
| PTP4A2 | 10739 |
| COPS7A | 10738 |
| CDC20 | 10732 |
| DPH3 | 10720 |
| UBA52 | 10707 |
| FPGT | 10685 |
| ACTB | 10683 |
| LARGE1 | 10682 |
| TPGS2 | 10668 |
| NOP58 | 10662 |
| EEF2 | 10659 |
| VCPIP1 | 10640 |
| PIAS4 | 10596 |
| ACTR10 | 10590 |
| RAB40C | 10588 |
| MGAT4A | 10584 |
| CD109 | 10579 |
| DCAF7 | 10568 |
| RPA1 | 10563 |
| MFGE8 | 10560 |
| VNN1 | 10554 |
| PIGZ | 10536 |
| NUP188 | 10521 |
| DOLPP1 | 10517 |
| GBF1 | 10507 |
| DPH6 | 10486 |
| BPIFB2 | 10473 |
| PSMB9 | 10430 |
| ATXN7 | 10416 |
| EIF5A2 | 10412 |
| COMMD5 | 10389 |
| EPAS1 | 10387 |
| SPTBN1 | 10356 |
| YKT6 | 10349 |
| NOD1 | 10348 |
| COPS8 | 10337 |
| PSMB6 | 10326 |
| WSB1 | 10308 |
| PSMC6 | 10307 |
| RAB31 | 10305 |
| KLHL42 | 10303 |
| CHM | 10293 |
| SNX3 | 10279 |
| DCAF4 | 10278 |
| CAPZA1 | 10272 |
| AMDHD2 | 10267 |
| B4GALT3 | 10265 |
| AREG | 10258 |
| NSF | 10249 |
| TRIM27 | 10241 |
| ST6GALNAC6 | 10212 |
| ARFGAP3 | 10209 |
| RNF181 | 10206 |
| PSMC4 | 10196 |
| UBE2H | 10168 |
| KAT2B | 10158 |
| TNKS | 10153 |
| COL7A1 | 10152 |
| GOLM1 | 10136 |
| NUP88 | 10134 |
| XPC | 10123 |
| FEM1C | 10115 |
| GALNT10 | 10114 |
| DCAF16 | 10105 |
| RUVBL1 | 10058 |
| SPSB3 | 10054 |
| NUP50 | 10047 |
| PTEN | 10023 |
| INCENP | 10005 |
| EVA1A | 9995 |
| FBXO44 | 9964 |
| CASP8AP2 | 9946 |
| CUL4B | 9945 |
| CDC73 | 9943 |
| RNF123 | 9939 |
| NR5A1 | 9936 |
| RABGGTA | 9926 |
| NCOA1 | 9914 |
| PIGM | 9913 |
| SP3 | 9908 |
| ANK1 | 9901 |
| HSPA8 | 9895 |
| METTL21A | 9883 |
| USP14 | 9882 |
| KDM1B | 9876 |
| PSMD9 | 9853 |
| COPS3 | 9810 |
| AGBL2 | 9809 |
| COMMD7 | 9798 |
| DCUN1D2 | 9784 |
| BIRC5 | 9771 |
| ASB9 | 9735 |
| RBBP7 | 9712 |
| TRAPPC2L | 9709 |
| PSMD5 | 9676 |
| GPLD1 | 9667 |
| STAM | 9665 |
| BRCA1 | 9663 |
| DCAF5 | 9642 |
| ST3GAL5 | 9630 |
| ARSD | 9613 |
| KLHL22 | 9610 |
| RFT1 | 9608 |
| CALU | 9602 |
| KAT2A | 9597 |
| MPI | 9596 |
| ST3GAL2 | 9594 |
| TGFA | 9574 |
| IGFBP4 | 9571 |
| ADAMTS13 | 9541 |
| NSMCE2 | 9534 |
| TRAPPC9 | 9528 |
| RTN4RL2 | 9479 |
| SEH1L | 9474 |
| BCL10 | 9472 |
| COMMD3 | 9446 |
| FBXO21 | 9436 |
| SMAD1 | 9435 |
| CTSC | 9398 |
| MBD1 | 9395 |
| RAB36 | 9394 |
| USP34 | 9391 |
| TNIP1 | 9381 |
| FAM20C | 9378 |
| ALG6 | 9374 |
| STS | 9373 |
| PSMD7 | 9371 |
| GALNT6 | 9366 |
| PSMD10 | 9356 |
| NCOR2 | 9331 |
| TMEM129 | 9321 |
| SUMO3 | 9299 |
| APOL1 | 9284 |
| PSMB7 | 9253 |
| CBX8 | 9242 |
| ALG1 | 9207 |
| SHISA5 | 9203 |
| USP15 | 9193 |
| NICN1 | 9177 |
| UBE2M | 9174 |
| MUC15 | 9153 |
| FOXK1 | 9151 |
| USP9X | 9136 |
| PIGF | 9133 |
| POLB | 9130 |
| FBXL4 | 9111 |
| NUP155 | 9102 |
| B3GNT9 | 9094 |
| COG7 | 9093 |
| TP53BP1 | 9089 |
| NCOA2 | 9072 |
| PHC1 | 9053 |
| PIGA | 9048 |
| FBXO22 | 9038 |
| SRD5A3 | 9027 |
| UBB | 9013 |
| DOHH | 9002 |
| ARF5 | 8998 |
| COG2 | 8997 |
| PEX12 | 8996 |
| RAB23 | 8961 |
| TRIM4 | 8937 |
| TUBA1A | 8932 |
| AXIN1 | 8908 |
| PSMA4 | 8902 |
| HGS | 8898 |
| NR1H3 | 8878 |
| RAB8B | 8875 |
| RAB40B | 8839 |
| BMI1 | 8838 |
| DCAF13 | 8826 |
| ASB1 | 8818 |
| DCAF8 | 8816 |
| NUDT14 | 8814 |
| HIF1A | 8807 |
| B3GNT3 | 8781 |
| AFP | 8777 |
| EEF1A1 | 8740 |
| CUL1 | 8725 |
| COG1 | 8708 |
| DTL | 8690 |
| PEX2 | 8675 |
| PSMD4 | 8670 |
| COPB1 | 8664 |
| MSLN | 8649 |
| PSMC5 | 8646 |
| SMAD2 | 8639 |
| PIGQ | 8638 |
| RXRA | 8607 |
| RAB11A | 8597 |
| MXRA8 | 8582 |
| CBX4 | 8580 |
| TMED3 | 8567 |
| NAGK | 8559 |
| GALNT7 | 8555 |
| RNF144A | 8547 |
| IDE | 8543 |
| TRAPPC3 | 8524 |
| POMGNT2 | 8517 |
| PLAUR | 8513 |
| NFRKB | 8510 |
| GGCX | 8504 |
| LY6E | 8481 |
| NR3C1 | 8476 |
| TULP4 | 8471 |
| UBE2D3 | 8449 |
| HIF3A | 8437 |
| RAB42 | 8434 |
| COG5 | 8389 |
| USP3 | 8383 |
| COPA | 8376 |
| DCTN2 | 8375 |
| THRB | 8360 |
| FBXL20 | 8336 |
| RAE1 | 8335 |
| CKAP4 | 8327 |
| WDR20 | 8319 |
| CUL7 | 8310 |
| IGFBP1 | 8301 |
| TNFAIP3 | 8284 |
| POMT1 | 8266 |
| UBA2 | 8263 |
| DYNC1LI2 | 8235 |
| CTR9 | 8230 |
| VCPKMT | 8222 |
| ASB7 | 8217 |
| CREBBP | 8214 |
| NAPG | 8187 |
| RAB3A | 8176 |
| COMMD1 | 8164 |
| PSMD12 | 8163 |
| FBXO11 | 8152 |
| PIGB | 8147 |
| KLHL13 | 8137 |
| IGFBP7 | 8108 |
| ASB4 | 8067 |
| PSME3 | 8052 |
| SERPINA10 | 7992 |
| MANEA | 7987 |
| FBXW11 | 7986 |
| PIGV | 7983 |
| GPC3 | 7971 |
| TUBB2B | 7952 |
| FBXO4 | 7948 |
| NUP85 | 7946 |
| NUP98 | 7940 |
| ACTR5 | 7892 |
| HERC2 | 7888 |
| ANKRD28 | 7882 |
| SENP2 | 7874 |
| RBX1 | 7850 |
| TOP2B | 7845 |
| APOA5 | 7816 |
| B4GAT1 | 7803 |
| RHOT1 | 7793 |
| TTLL7 | 7789 |
| APOE | 7759 |
| RAB15 | 7753 |
| NRN1L | 7736 |
| TGFBR2 | 7714 |
| RING1 | 7710 |
| GAN | 7702 |
| PEX14 | 7694 |
| DCTN5 | 7690 |
| TUBB8 | 7651 |
| DYNC1H1 | 7639 |
| RAB24 | 7638 |
| SERPINA1 | 7622 |
| ZNF131 | 7607 |
| TRRAP | 7571 |
| RNF168 | 7562 |
| MAN1B1 | 7534 |
| ADRM1 | 7511 |
| KCTD7 | 7510 |
| FBXO6 | 7468 |
| COMMD9 | 7455 |
| INO80E | 7449 |
| SLC35A1 | 7418 |
| USO1 | 7413 |
| GPS1 | 7406 |
| NUB1 | 7395 |
| GOLGB1 | 7386 |
| SPTBN2 | 7379 |
| USP12 | 7363 |
| RAB1B | 7340 |
| ADAMTSL2 | 7330 |
| RPS2 | 7293 |
| DCAF17 | 7273 |
| JOSD2 | 7257 |
| ETFBKMT | 7248 |
| USP37 | 7241 |
| LMAN1 | 7220 |
| LMAN2L | 7218 |
| LAMB1 | 7198 |
| ADAMTS1 | 7179 |
| MAP3K7 | 7172 |
| INO80 | 7157 |
| UBE2A | 7140 |
| UBE2E1 | 7102 |
| CST3 | 7101 |
| RAB13 | 7089 |
| MPDU1 | 7080 |
| FBXW8 | 7078 |
| ATXN3 | 7075 |
| PHC2 | 7072 |
| KLHL9 | 7071 |
| CDKN2A | 7056 |
| GMDS | 7053 |
| STAG1 | 7037 |
| GCNT4 | 7025 |
| APLP2 | 7009 |
| MGAT2 | 7002 |
| MDC1 | 6989 |
| DDX17 | 6985 |
| INO80D | 6967 |
| RAB1A | 6957 |
| RAB14 | 6952 |
| DAXX | 6929 |
| FBXO27 | 6911 |
| KLHL2 | 6866 |
| KIN | 6833 |
| ST3GAL6 | 6829 |
| ARRB2 | 6824 |
| B3GNT8 | 6820 |
| CD59 | 6818 |
| FBXO15 | 6797 |
| TRAPPC2 | 6775 |
| GALNT3 | 6774 |
| KTN1 | 6769 |
| TNKS2 | 6742 |
| UBE2D1 | 6734 |
| ALG14 | 6723 |
| BET1L | 6669 |
| BIRC3 | 6654 |
| DHPS | 6649 |
| PPARG | 6636 |
| UBD | 6630 |
| ACTR8 | 6616 |
| RANGAP1 | 6615 |
| ZBED1 | 6594 |
| UBE2L3 | 6589 |
| SEM1 | 6566 |
| RAB5C | 6565 |
| RCN1 | 6562 |
| FN1 | 6525 |
| MBD5 | 6524 |
| TDG | 6520 |
| PIGP | 6509 |
| XRCC4 | 6479 |
| TRIM28 | 6471 |
| UBE2V2 | 6467 |
| DNMT3A | 6452 |
| LEO1 | 6444 |
| KLHL20 | 6424 |
| PSMA3 | 6422 |
| RNF139 | 6382 |
| COPS6 | 6380 |
| SEC22A | 6374 |
| NUP54 | 6371 |
| SUMO1 | 6365 |
| CUL3 | 6363 |
| COPS5 | 6317 |
| ELOB | 6272 |
| COG6 | 6266 |
| THRA | 6251 |
| ASGR2 | 6225 |
| RAB33B | 6213 |
| SAR1B | 6198 |
| DPM3 | 6189 |
| POMGNT1 | 6187 |
| APOB | 6172 |
| RAB4B | 6116 |
| C1GALT1C1 | 6112 |
| SATB2 | 6101 |
| PSMD8 | 6091 |
| RAD23B | 6054 |
| NGLY1 | 6049 |
| BECN1 | 6036 |
| SMAD7 | 6006 |
| RIPK1 | 6000 |
| FBXL22 | 5990 |
| TPST2 | 5975 |
| VDAC2 | 5966 |
| ALB | 5965 |
| TRAPPC1 | 5956 |
| LARGE2 | 5939 |
| STAM2 | 5933 |
| MAN1C1 | 5920 |
| USP5 | 5894 |
| USP8 | 5864 |
| WRN | 5841 |
| HNRNPK | 5839 |
| ASB3 | 5827 |
| TOMM70 | 5819 |
| RAB27A | 5804 |
| USP24 | 5792 |
| DYNC1I2 | 5783 |
| RPS27A | 5776 |
| BAP1 | 5752 |
| TOPORS | 5743 |
| ICMT | 5741 |
| UHRF2 | 5740 |
| BABAM1 | 5721 |
| PARP1 | 5715 |
| AAAS | 5701 |
| ADAMTSL3 | 5688 |
| KBTBD8 | 5662 |
| SEC23A | 5659 |
| PSMA5 | 5657 |
| FBXL8 | 5631 |
| AMFR | 5612 |
| RAB5B | 5611 |
| EID3 | 5599 |
| HDAC1 | 5563 |
| B4GALT6 | 5555 |
| ADAMTS7 | 5554 |
| ARSA | 5552 |
| ADAM10 | 5549 |
| PMM1 | 5521 |
| UBE2E3 | 5512 |
| TTL | 5487 |
| RELA | 5468 |
| VWA1 | 5457 |
| TGFBR1 | 5447 |
| STAG2 | 5443 |
| FBXL14 | 5439 |
| INO80B | 5426 |
| GANAB | 5417 |
| NUP43 | 5410 |
| USP21 | 5405 |
| HIC1 | 5389 |
| GALNT16 | 5384 |
| UBE2B | 5375 |
| CYR61 | 5367 |
| PSMD13 | 5353 |
| HLA-B | 5329 |
| USP11 | 5328 |
| FBXW7 | 5325 |
| MDM4 | 5318 |
| SMAD4 | 5290 |
| RAB26 | 5288 |
| FBXW10 | 5268 |
| DYNC1LI1 | 5237 |
| TUBB1 | 5236 |
| NUP153 | 5230 |
| GAS6 | 5226 |
| FUCA1 | 5210 |
| RAB21 | 5208 |
| ANKRD9 | 5202 |
| PARK7 | 5199 |
| OTULIN | 5175 |
| PEX10 | 5162 |
| B4GALT2 | 5152 |
| ALG10 | 5133 |
| DCAF6 | 5119 |
| UBE2Q2 | 5107 |
| SP100 | 5083 |
| ADAMTS17 | 5058 |
| ARF3 | 5040 |
| RRAGA | 5038 |
| B3GALNT2 | 5034 |
| AGBL5 | 5032 |
| B4GALT4 | 5027 |
| USP19 | 5014 |
| STX17 | 4997 |
| ERCC8 | 4995 |
| TRAPPC6B | 4993 |
| GPAA1 | 4990 |
| DNAJC24 | 4977 |
| FUOM | 4976 |
| WDR5 | 4953 |
| PSMC2 | 4948 |
| SMC3 | 4924 |
| B3GNT2 | 4879 |
| PSME1 | 4861 |
| THBS2 | 4856 |
| DYNLL1 | 4853 |
| OTUD3 | 4849 |
| CDH2 | 4845 |
| MAN2A2 | 4840 |
| DPH7 | 4778 |
| PRKDC | 4777 |
| POMK | 4768 |
| CCDC8 | 4762 |
| VASH1 | 4751 |
| SUDS3 | 4748 |
| RNF2 | 4732 |
| MOGS | 4728 |
| GALNT4 | 4706 |
| UBA6 | 4704 |
| CUL4A | 4702 |
| RAB8A | 4658 |
| USP48 | 4648 |
| TECTA | 4639 |
| DHDDS | 4636 |
| GNPNAT1 | 4628 |
| OBSL1 | 4622 |
| SPTAN1 | 4610 |
| NUP58 | 4603 |
| TMEM132A | 4597 |
| NEURL2 | 4562 |
| BRCC3 | 4560 |
| METTL22 | 4532 |
| DAG1 | 4498 |
| PIGO | 4481 |
| RAB4A | 4453 |
| ST8SIA1 | 4428 |
| TPST1 | 4399 |
| DPM2 | 4373 |
| FBXL19 | 4369 |
| TGOLN2 | 4352 |
| SMC5 | 4328 |
| CHGB | 4319 |
| STAMBPL1 | 4302 |
| FOXO4 | 4276 |
| ZNF350 | 4246 |
| SMC6 | 4184 |
| NPM1 | 4183 |
| FBXL3 | 4168 |
| DNMT1 | 4159 |
| PIGC | 4155 |
| RFWD2 | 4150 |
| TP53 | 4144 |
| FGF23 | 4091 |
| UBE2W | 4047 |
| CNIH3 | 4025 |
| ETFB | 4002 |
| DCTN4 | 3979 |
| NUP214 | 3957 |
| SVBP | 3948 |
| PSMB3 | 3928 |
| TTLL4 | 3926 |
| OTUD7B | 3920 |
| ASXL1 | 3914 |
| LTBP1 | 3905 |
| EDEM3 | 3904 |
| LRRC41 | 3889 |
| DCUN1D5 | 3884 |
| ASGR1 | 3870 |
| COG4 | 3852 |
| PIGH | 3848 |
| UBE2S | 3839 |
| USP47 | 3795 |
| FBXO9 | 3776 |
| USP33 | 3761 |
| B3GNT4 | 3741 |
| ST6GAL1 | 3739 |
| GORASP1 | 3727 |
| APC | 3716 |
| MYC | 3708 |
| TRIM13 | 3695 |
| PSMB2 | 3678 |
| NEGR1 | 3667 |
| AGBL3 | 3660 |
| RAB39B | 3618 |
| UBE2N | 3604 |
| PAF1 | 3589 |
| ST8SIA5 | 3583 |
| RTF1 | 3574 |
| HNRNPC | 3563 |
| MTA1 | 3553 |
| RAB3B | 3544 |
| SAE1 | 3527 |
| TRAPPC4 | 3487 |
| CCDC22 | 3481 |
| SEC22C | 3433 |
| CHML | 3428 |
| ITIH2 | 3417 |
| USP28 | 3404 |
| CAND1 | 3381 |
| MGAT4C | 3364 |
| MAT2B | 3339 |
| DCTN1 | 3338 |
| MAVS | 3323 |
| ARFGAP1 | 3224 |
| RAB29 | 3213 |
| RAB10 | 3205 |
| FEM1A | 3196 |
| RAB3D | 3155 |
| TRAF6 | 3150 |
| CAPZA2 | 3143 |
| SPP2 | 3138 |
| B3GNT7 | 3122 |
| MUC13 | 3097 |
| SUMO2 | 3089 |
| PSMC3 | 3070 |
| FBXL18 | 3067 |
| GLB1 | 3064 |
| NDC1 | 3023 |
| NR3C2 | 2999 |
| HDAC4 | 2998 |
| MCRS1 | 2985 |
| NSMCE4A | 2966 |
| DCTN3 | 2887 |
| USP4 | 2874 |
| PREB | 2868 |
| DCUN1D1 | 2843 |
| UGGT2 | 2839 |
| USP49 | 2797 |
| RAB2B | 2784 |
| RAB6B | 2780 |
| PIAS3 | 2775 |
| ACTL6A | 2772 |
| RNF128 | 2768 |
| B3GNTL1 | 2766 |
| B4GALNT2 | 2758 |
| BTRC | 2757 |
| SOCS2 | 2710 |
| NUP133 | 2708 |
| ALG13 | 2687 |
| PIGN | 2662 |
| CHD3 | 2661 |
| UBE2I | 2653 |
| TNIP2 | 2640 |
| FN3K | 2638 |
| NFKB2 | 2634 |
| SPSB2 | 2622 |
| WDTC1 | 2617 |
| LAMC1 | 2611 |
| MEN1 | 2581 |
| RAB6A | 2578 |
| CCNF | 2569 |
| TUBB2A | 2568 |
| UBA3 | 2562 |
| ARFGAP2 | 2547 |
| ARSK | 2519 |
| QSOX1 | 2518 |
| LMO7 | 2512 |
| DPM1 | 2494 |
| CUL5 | 2485 |
| KLHL11 | 2475 |
| USP20 | 2470 |
| TUSC3 | 2465 |
| TADA3 | 2462 |
| ADAMTS4 | 2448 |
| GOSR2 | 2441 |
| AURKA | 2412 |
| TFPT | 2390 |
| CAPZB | 2376 |
| PIGT | 2351 |
| PSMB4 | 2330 |
| FBXL12 | 2320 |
| RCE1 | 2289 |
| TUBB6 | 2268 |
| CPM | 2250 |
| ASB8 | 2243 |
| ADAMTSL5 | 2224 |
| UBXN7 | 2192 |
| ALG8 | 2188 |
| SUMF2 | 2158 |
| NSMCE3 | 2144 |
| SPSB1 | 2118 |
| MAN2A1 | 2117 |
| PIGU | 2112 |
| MYSM1 | 2098 |
| VDAC1 | 2092 |
| TTLL9 | 2086 |
| MAN1A1 | 2084 |
| MUC20 | 2082 |
| PSMB1 | 2062 |
| PML | 2057 |
| KLHL5 | 2025 |
| USP10 | 1999 |
| CEACAM5 | 1981 |
| UBE2Z | 1959 |
| MDM2 | 1942 |
| KDELR3 | 1922 |
| CAMKMT | 1898 |
| DDX58 | 1883 |
| RAB12 | 1872 |
| PIGY | 1867 |
| FBXO7 | 1865 |
| UBE2D2 | 1857 |
| UAP1 | 1828 |
| PSMA7 | 1820 |
| SENP1 | 1811 |
| RAB11B | 1793 |
| FBXL13 | 1783 |
| FBXW9 | 1747 |
| COPS7B | 1713 |
| EEF2KMT | 1703 |
| SEC22B | 1690 |
| PHC3 | 1660 |
| GALNT1 | 1659 |
| GALNT13 | 1646 |
| F5 | 1638 |
| RNF146 | 1622 |
| GP2 | 1595 |
| IKBKE | 1593 |
| L3MBTL2 | 1567 |
| SMC1A | 1560 |
| COPZ1 | 1554 |
| UBC | 1551 |
| C1GALT1 | 1485 |
| PSMB5 | 1484 |
| F8 | 1460 |
| PEX13 | 1454 |
| UBE2G2 | 1451 |
| TTLL5 | 1443 |
| ING2 | 1437 |
| BST1 | 1408 |
| COMMD8 | 1404 |
| CALM1 | 1340 |
| GCNT1 | 1328 |
| TOMM20 | 1324 |
| PRSS23 | 1288 |
| LRRC49 | 1273 |
| PPP6R3 | 1271 |
| ELOC | 1265 |
| RNF7 | 1249 |
| F2 | 1246 |
| PIGS | 1243 |
| ASB18 | 1231 |
| TAF10 | 1223 |
| GOSR1 | 1215 |
| FBXL15 | 1200 |
| TRAF2 | 1180 |
| RAD21 | 1178 |
| OTUD7A | 1152 |
| TTLL12 | 1140 |
| NEDD8 | 1131 |
| SKP1 | 1117 |
| NRIP1 | 1114 |
| TPR | 1105 |
| WDR48 | 1063 |
| NR2C1 | 1052 |
| UBA1 | 1021 |
| BIRC2 | 1007 |
| LRR1 | 1000 |
| LAMB2 | 978 |
| SCFD1 | 960 |
| NANP | 957 |
| BET1 | 896 |
| WDR61 | 889 |
| PSMD11 | 879 |
| UCHL5 | 875 |
| ALG9 | 865 |
| TUBB3 | 858 |
| NAPB | 853 |
| PSMB10 | 838 |
| DCUN1D4 | 815 |
| UBE2R2 | 790 |
| COMMD2 | 774 |
| SEC23IP | 767 |
| PIAS2 | 761 |
| RAB18 | 760 |
| UBE2K | 750 |
| TRAF3 | 729 |
| PEX5 | 707 |
| CUL2 | 703 |
| HDAC2 | 693 |
| NUP160 | 683 |
| USP25 | 676 |
| DCTN6 | 666 |
| SUZ12 | 664 |
| NUP62 | 618 |
| LYPD3 | 613 |
| FBXW2 | 602 |
| OTUB1 | 600 |
| ANK3 | 591 |
| RAB30 | 562 |
| VDAC3 | 561 |
| PIAS1 | 560 |
| POFUT2 | 542 |
| B4GALT1 | 540 |
| MITF | 519 |
| BGLAP | 475 |
| TRAPPC5 | 470 |
| KLHL25 | 441 |
| CNIH1 | 416 |
| INO80C | 380 |
| NR1H2 | 373 |
| KCTD6 | 368 |
| ANO8 | 350 |
| SDC2 | 289 |
| FBXO30 | 270 |
| PSMA6 | 261 |
| USP7 | 258 |
| HDAC7 | 254 |
| RNF135 | 247 |
| COMMD10 | 233 |
| DOLK | 213 |
| FEM1B | 209 |
| RBBP5 | 204 |
| OTOA | 171 |
| FBXO2 | 158 |
| PIGX | 124 |
| BTBD1 | 81 |
| CTBP1 | 73 |
| AHSG | 62 |
| COPS4 | 51 |
| FBXO10 | 43 |
| RANBP2 | 9 |
| COMMD4 | 7 |
Initial triggering of complement
| 517 | |
|---|---|
| set | Initial triggering of complement |
| setSize | 12 |
| pANOVA | 4.38e-06 |
| s.dist | 0.765 |
| p.adjustANOVA | 0.000402 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| C1S | 14430 |
| C3 | 14417 |
| CFB | 14394 |
| C4A | 14381 |
| C4B | 14173 |
| C1R | 13954 |
| MBL2 | 13247 |
| MASP1 | 12716 |
| COLEC11 | 12595 |
| MASP2 | 10923 |
| CFD | 10570 |
| C2 | 8098 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| C1S | 14430 |
| C3 | 14417 |
| CFB | 14394 |
| C4A | 14381 |
| C4B | 14173 |
| C1R | 13954 |
| MBL2 | 13247 |
| MASP1 | 12716 |
| COLEC11 | 12595 |
| MASP2 | 10923 |
| CFD | 10570 |
| C2 | 8098 |
Metabolism of lipids
| 624 | |
|---|---|
| set | Metabolism of lipids |
| setSize | 592 |
| pANOVA | 7.79e-06 |
| s.dist | 0.108 |
| p.adjustANOVA | 0.00067 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SEC24D | 14520 |
| MSMO1 | 14517 |
| AKR1C2 | 14496 |
| CYP1A1 | 14494 |
| MTMR4 | 14488 |
| AKR1C1 | 14484 |
| HMGCS1 | 14473 |
| SQLE | 14468 |
| IDI1 | 14452 |
| ACSM3 | 14445 |
| FADS1 | 14413 |
| HMGCR | 14408 |
| ACSF2 | 14400 |
| ARSG | 14366 |
| MVK | 14363 |
| ACSL1 | 14340 |
| DHCR7 | 14319 |
| ACSL4 | 14281 |
| ARSB | 14246 |
| SREBF2 | 14223 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SEC24D | 14520 |
| MSMO1 | 14517 |
| AKR1C2 | 14496 |
| CYP1A1 | 14494 |
| MTMR4 | 14488 |
| AKR1C1 | 14484 |
| HMGCS1 | 14473 |
| SQLE | 14468 |
| IDI1 | 14452 |
| ACSM3 | 14445 |
| FADS1 | 14413 |
| HMGCR | 14408 |
| ACSF2 | 14400 |
| ARSG | 14366 |
| MVK | 14363 |
| ACSL1 | 14340 |
| DHCR7 | 14319 |
| ACSL4 | 14281 |
| ARSB | 14246 |
| SREBF2 | 14223 |
| MVD | 14220 |
| PNPLA3 | 14198 |
| CYP4F2 | 14196 |
| CYP4F3 | 14195 |
| PLD1 | 14191 |
| FDFT1 | 14189 |
| PNPLA6 | 14177 |
| CHKA | 14176 |
| LSS | 14165 |
| ACBD4 | 14149 |
| ACAD10 | 14120 |
| PLA2G2A | 14102 |
| ELOVL6 | 14093 |
| SEC24A | 14088 |
| TXNRD1 | 14041 |
| SPTSSB | 14034 |
| ABCB4 | 14032 |
| TRIB3 | 14029 |
| PTDSS1 | 14025 |
| SLC51B | 14011 |
| ESRRA | 13960 |
| NEU1 | 13953 |
| LPIN3 | 13949 |
| NCOA6 | 13941 |
| LPIN2 | 13908 |
| PPARA | 13906 |
| ESYT2 | 13884 |
| OSBP | 13854 |
| PITPNB | 13834 |
| GBA | 13831 |
| OSBPL2 | 13812 |
| ACOT13 | 13798 |
| ASAH1 | 13777 |
| GDPD1 | 13747 |
| PCCA | 13733 |
| AGT | 13674 |
| NEU3 | 13653 |
| CPT1A | 13626 |
| HMGCL | 13619 |
| FADS2 | 13609 |
| ESYT1 | 13601 |
| LPCAT2 | 13599 |
| ACOT2 | 13592 |
| FAAH2 | 13577 |
| AMACR | 13555 |
| EHHADH | 13541 |
| RAN | 13497 |
| EP300 | 13485 |
| MAPKAPK2 | 13468 |
| HEXB | 13459 |
| APOA1 | 13433 |
| SCD | 13413 |
| GPX2 | 13379 |
| GPAM | 13366 |
| CERS2 | 13365 |
| ACAT2 | 13351 |
| ANGPTL4 | 13342 |
| NEU4 | 13335 |
| KPNB1 | 13324 |
| MID1IP1 | 13308 |
| HMGCS2 | 13280 |
| PIP4K2C | 13241 |
| GRHL1 | 13217 |
| ARV1 | 13201 |
| B4GALNT1 | 13199 |
| APOA2 | 13191 |
| SLC44A2 | 13182 |
| BDH2 | 13164 |
| CTSA | 13149 |
| ALDH3B1 | 13143 |
| DECR1 | 13133 |
| ACOT9 | 13115 |
| OCRL | 13103 |
| MIGA2 | 13080 |
| ABCD1 | 13062 |
| SEC24C | 13047 |
| AKR1B1 | 13033 |
| SULT2A1 | 13013 |
| SLC25A20 | 13011 |
| FDPS | 12999 |
| GPAT4 | 12941 |
| GPAT3 | 12906 |
| CYP51A1 | 12901 |
| HSD17B11 | 12833 |
| ACSL3 | 12797 |
| GBA2 | 12790 |
| TM7SF2 | 12785 |
| PITPNM1 | 12747 |
| DEGS1 | 12708 |
| ANKRD1 | 12704 |
| NR1H4 | 12674 |
| ARF1 | 12642 |
| INPP5K | 12614 |
| STARD10 | 12612 |
| PNPLA8 | 12549 |
| MBTPS1 | 12523 |
| SCP2 | 12518 |
| LPCAT4 | 12504 |
| ABCC1 | 12501 |
| PTGR2 | 12490 |
| GSTM4 | 12476 |
| INSIG2 | 12407 |
| PCYT1B | 12394 |
| ACADM | 12392 |
| SIN3A | 12373 |
| RORA | 12360 |
| PPARGC1A | 12350 |
| PHYH | 12345 |
| CYP19A1 | 12287 |
| AKR1B15 | 12286 |
| MECR | 12270 |
| HACD2 | 12269 |
| MED29 | 12264 |
| HACD3 | 12248 |
| NUDT19 | 12180 |
| GDPD3 | 12123 |
| CYP27B1 | 12039 |
| FIG4 | 12002 |
| CERS6 | 11969 |
| SPTLC3 | 11964 |
| SCAP | 11960 |
| HSD17B12 | 11955 |
| ABCC3 | 11944 |
| LTA4H | 11893 |
| NSDHL | 11890 |
| MOGAT3 | 11883 |
| SLC25A1 | 11880 |
| PECR | 11877 |
| GLA | 11875 |
| ACOT11 | 11870 |
| ACOX1 | 11824 |
| RGL1 | 11795 |
| PTGR1 | 11789 |
| SUMF1 | 11754 |
| FAAH | 11722 |
| MED22 | 11676 |
| ARSI | 11653 |
| MCEE | 11652 |
| PLEKHA3 | 11648 |
| LPIN1 | 11643 |
| EPHX2 | 11635 |
| SLC51A | 11608 |
| CBR1 | 11607 |
| PIP4K2A | 11582 |
| PLA2G6 | 11578 |
| GPD1 | 11575 |
| THEM4 | 11571 |
| ACP6 | 11552 |
| RUFY1 | 11544 |
| SEC24B | 11541 |
| ACACB | 11531 |
| MED1 | 11468 |
| PITPNM3 | 11438 |
| CYP2U1 | 11416 |
| SP1 | 11396 |
| NPAS2 | 11394 |
| RAB5A | 11392 |
| PLIN3 | 11389 |
| PLEKHA6 | 11356 |
| VAC14 | 11319 |
| PNPLA2 | 11306 |
| ELOVL1 | 11234 |
| MED13 | 11168 |
| MOGAT2 | 11122 |
| AHR | 11075 |
| HADH | 11065 |
| DHCR24 | 11041 |
| PIK3C3 | 11026 |
| PSAP | 11023 |
| PCTP | 10959 |
| MED7 | 10922 |
| FITM1 | 10904 |
| SMPD4 | 10896 |
| CHPT1 | 10889 |
| PPP1CA | 10883 |
| DECR2 | 10859 |
| ELOVL5 | 10783 |
| CYP11A1 | 10772 |
| MED30 | 10702 |
| CERS4 | 10687 |
| MED20 | 10676 |
| ACADS | 10658 |
| CSNK2A1 | 10637 |
| AGPS | 10633 |
| PIAS4 | 10596 |
| ACER2 | 10591 |
| STARD5 | 10571 |
| ACOT8 | 10550 |
| CIDEC | 10542 |
| CPT2 | 10519 |
| GGPS1 | 10498 |
| TECR | 10471 |
| SLC27A1 | 10421 |
| VAPA | 10346 |
| MTMR14 | 10343 |
| MED26 | 10313 |
| SGMS1 | 10257 |
| ABHD5 | 10203 |
| TMEM86B | 10186 |
| PIK3CD | 10102 |
| MED15 | 10099 |
| SC5D | 10071 |
| ECI2 | 10067 |
| CDS1 | 10059 |
| ACBD5 | 10037 |
| PTEN | 10023 |
| PCYT2 | 10019 |
| ACAD11 | 10011 |
| GM2A | 9989 |
| GLIPR1 | 9959 |
| CD36 | 9953 |
| AACS | 9934 |
| NCOA1 | 9914 |
| ACSL6 | 9898 |
| STARD3 | 9872 |
| MED17 | 9850 |
| CHD9 | 9842 |
| NR1D1 | 9818 |
| AHRR | 9804 |
| CYP39A1 | 9791 |
| ASAH2 | 9785 |
| LPCAT1 | 9761 |
| EBP | 9739 |
| ALDH3A2 | 9706 |
| NUDT7 | 9681 |
| CSNK2A2 | 9641 |
| FABP1 | 9636 |
| NFYB | 9634 |
| ARSD | 9613 |
| GPS2 | 9607 |
| ORMDL3 | 9537 |
| OSBPL10 | 9510 |
| AGPAT3 | 9468 |
| ENPP7 | 9404 |
| FAM120B | 9402 |
| PI4KA | 9385 |
| STS | 9373 |
| NCOR2 | 9331 |
| GLB1L | 9326 |
| PIK3R1 | 9259 |
| NCOR1 | 9256 |
| MIGA1 | 9221 |
| MED9 | 9189 |
| HEXA | 9171 |
| HSD17B8 | 9165 |
| STAR | 9140 |
| OSBPL3 | 9104 |
| OSBPL9 | 9090 |
| HELZ2 | 9086 |
| NCOA2 | 9072 |
| STARD4 | 9071 |
| MTMR12 | 9063 |
| AGPAT2 | 9047 |
| TBXAS1 | 9044 |
| CDK8 | 9040 |
| SRD5A3 | 9027 |
| CPTP | 8966 |
| PLA2G4B | 8953 |
| PLPP6 | 8931 |
| NR1H3 | 8878 |
| ACER3 | 8870 |
| SLC44A3 | 8864 |
| MED13L | 8847 |
| SAMD8 | 8833 |
| PEX11A | 8829 |
| MED11 | 8686 |
| ACLY | 8659 |
| ESYT3 | 8615 |
| RXRA | 8607 |
| GPCPD1 | 8532 |
| GGT5 | 8488 |
| PITPNM2 | 8457 |
| TAZ | 8445 |
| CRAT | 8427 |
| INPP5F | 8411 |
| CSNK2B | 8368 |
| SYNJ1 | 8367 |
| MTF1 | 8354 |
| HILPDA | 8332 |
| SLCO1B3 | 8303 |
| ABHD3 | 8280 |
| PNPLA4 | 8265 |
| PCYT1A | 8255 |
| CYP21A2 | 8249 |
| HSD17B2 | 8238 |
| CREBBP | 8214 |
| ACSBG1 | 8106 |
| PTDSS2 | 8095 |
| PLEKHA5 | 8030 |
| CYP27A1 | 7994 |
| ACADVL | 7903 |
| GPX4 | 7884 |
| CPNE1 | 7836 |
| APOA5 | 7816 |
| BDH1 | 7748 |
| PPP1CB | 7685 |
| PLD2 | 7673 |
| ACAA2 | 7672 |
| SIN3B | 7646 |
| FABP5 | 7635 |
| PGS1 | 7623 |
| BAAT | 7606 |
| SREBF1 | 7517 |
| TNFAIP8 | 7470 |
| INPP5D | 7467 |
| MTMR9 | 7392 |
| ACAA1 | 7384 |
| SGMS2 | 7378 |
| ELOVL7 | 7372 |
| THRAP3 | 7364 |
| CPT1B | 7323 |
| AGPAT1 | 7309 |
| TMEM55B | 7246 |
| ACOT7 | 7200 |
| PLIN1 | 7186 |
| PPP1CC | 7149 |
| SBF1 | 7143 |
| LPCAT3 | 7121 |
| OSBPL7 | 7117 |
| PTGES3 | 7103 |
| ACOX3 | 7093 |
| MBTPS2 | 7019 |
| CYP3A4 | 6964 |
| RAB14 | 6952 |
| LCLAT1 | 6935 |
| ETNK2 | 6918 |
| PON3 | 6884 |
| PTGES2 | 6882 |
| SPTLC1 | 6875 |
| TIAM2 | 6863 |
| SCD5 | 6855 |
| ARNT2 | 6853 |
| PPARGC1B | 6846 |
| PLPP1 | 6845 |
| MCAT | 6837 |
| CYP2E1 | 6804 |
| PLD6 | 6800 |
| VAPB | 6785 |
| PIP5K1C | 6778 |
| OSBPL8 | 6767 |
| SLC25A17 | 6764 |
| OXCT2 | 6756 |
| AKR1C4 | 6744 |
| CARM1 | 6725 |
| MED18 | 6710 |
| PI4K2A | 6701 |
| MED12 | 6690 |
| CYP2R1 | 6680 |
| LBR | 6666 |
| PPARG | 6636 |
| DPEP1 | 6625 |
| PLPP3 | 6619 |
| SPHK1 | 6587 |
| NRF1 | 6553 |
| PNPLA7 | 6544 |
| MLYCD | 6512 |
| CHKB | 6506 |
| PMVK | 6407 |
| PIK3C2B | 6385 |
| PRKAA2 | 6357 |
| CPNE3 | 6354 |
| ALAS1 | 6320 |
| PRKD2 | 6289 |
| ETNPPL | 6239 |
| SAR1B | 6198 |
| ACBD7 | 6158 |
| MTMR6 | 6138 |
| GPX1 | 6089 |
| ACOT1 | 6078 |
| CRLS1 | 6066 |
| AGPAT5 | 6047 |
| DHRS7B | 6034 |
| ALB | 5965 |
| FDXR | 5910 |
| PIK3CA | 5849 |
| ELOVL2 | 5746 |
| MED27 | 5729 |
| PPM1L | 5684 |
| MED23 | 5679 |
| SEC23A | 5659 |
| PLA2G15 | 5653 |
| HADHA | 5626 |
| MED4 | 5601 |
| ARSA | 5552 |
| GPD1L | 5544 |
| SLC44A5 | 5540 |
| HSD3B7 | 5445 |
| PLEKHA2 | 5432 |
| INPP5E | 5431 |
| SGPP1 | 5415 |
| PIK3CB | 5379 |
| ACSS3 | 5303 |
| INPP5J | 5266 |
| DEGS2 | 5232 |
| NFYA | 5142 |
| CCNC | 5121 |
| PIP4K2B | 5102 |
| GC | 5084 |
| ACBD6 | 5076 |
| ARF3 | 5040 |
| HSD17B7 | 5017 |
| CERS1 | 4891 |
| SPHK2 | 4877 |
| ACAT1 | 4838 |
| NCOA3 | 4825 |
| SPTSSA | 4796 |
| MORC2 | 4784 |
| ABCA1 | 4752 |
| FDX1 | 4743 |
| GALC | 4735 |
| PIK3R3 | 4734 |
| LPGAT1 | 4666 |
| HSD17B1 | 4656 |
| CYP24A1 | 4653 |
| TNFAIP8L1 | 4624 |
| GDPD5 | 4613 |
| STARD7 | 4611 |
| PEMT | 4605 |
| MTMR3 | 4570 |
| MTMR10 | 4553 |
| UGT8 | 4511 |
| TNFRSF21 | 4491 |
| PIKFYVE | 4479 |
| SMARCD3 | 4455 |
| RAB4A | 4453 |
| ETNK1 | 4448 |
| DGAT2 | 4420 |
| MED28 | 4339 |
| ACSF3 | 4297 |
| MBOAT7 | 4241 |
| AKR1D1 | 4223 |
| SLC44A1 | 4205 |
| TGS1 | 4181 |
| NDUFAB1 | 4114 |
| MED6 | 4113 |
| SLCO1A2 | 4048 |
| PLEKHA1 | 4043 |
| SELENOI | 4039 |
| AGK | 4016 |
| SLC22A5 | 3989 |
| PTPMT1 | 3929 |
| LIPH | 3871 |
| HSD17B4 | 3810 |
| MMAA | 3808 |
| CDIPT | 3801 |
| SERPINA6 | 3759 |
| PIP5K1A | 3743 |
| PI4KB | 3711 |
| DDHD1 | 3709 |
| FASN | 3698 |
| ORMDL2 | 3614 |
| PRKAB2 | 3594 |
| SMPD1 | 3537 |
| FHL2 | 3504 |
| ACSL5 | 3496 |
| PCCB | 3460 |
| FITM2 | 3457 |
| PRKACA | 3407 |
| SPTLC2 | 3399 |
| CLOCK | 3360 |
| TBL1X | 3308 |
| SYNJ2 | 3280 |
| ACOXL | 3244 |
| SRD5A1 | 3243 |
| CYP7A1 | 3133 |
| SUMO2 | 3089 |
| GLB1 | 3064 |
| SLC27A5 | 3043 |
| CDK19 | 2984 |
| MED14 | 2943 |
| PLEKHA4 | 2901 |
| OSBPL6 | 2900 |
| PRKACB | 2885 |
| PTGIS | 2883 |
| CERK | 2848 |
| PLA2G4C | 2813 |
| TBL1XR1 | 2795 |
| PIK3R2 | 2728 |
| HACL1 | 2718 |
| MED19 | 2717 |
| PRKD3 | 2712 |
| PRKD1 | 2704 |
| GLTP | 2660 |
| PPT1 | 2656 |
| UBE2I | 2653 |
| KDSR | 2642 |
| HSD17B13 | 2635 |
| ARSK | 2519 |
| MED25 | 2466 |
| PLD3 | 2446 |
| SBF2 | 2408 |
| UGCG | 2377 |
| CROT | 2357 |
| ACHE | 2348 |
| CSNK1G2 | 2329 |
| MED10 | 2313 |
| PIK3R4 | 2219 |
| PI4K2B | 2175 |
| GK | 2160 |
| SUMF2 | 2158 |
| OSBPL1A | 2101 |
| CYP2D6 | 2056 |
| PIP5K1B | 2051 |
| ARNT | 1996 |
| LGMN | 1966 |
| CBR4 | 1961 |
| STARD3NL | 1953 |
| CEPT1 | 1789 |
| ACOX2 | 1774 |
| RXRB | 1725 |
| SMPD3 | 1715 |
| CUBN | 1678 |
| CDS2 | 1637 |
| SLC27A2 | 1635 |
| PLA2G12A | 1614 |
| PPARD | 1594 |
| PON1 | 1585 |
| CYP2J2 | 1505 |
| GDE1 | 1502 |
| FABP2 | 1471 |
| PISD | 1470 |
| MTMR1 | 1468 |
| MED21 | 1457 |
| MED24 | 1445 |
| NFYC | 1395 |
| MTMR2 | 1361 |
| HSD11B2 | 1264 |
| ORMDL1 | 1227 |
| MED16 | 1198 |
| INPPL1 | 1197 |
| PLIN2 | 1183 |
| PON2 | 1101 |
| DDHD2 | 1093 |
| DBI | 1034 |
| AGMO | 1027 |
| HSD17B14 | 944 |
| CYP4F11 | 904 |
| SMPD2 | 823 |
| GNPAT | 822 |
| SLC27A3 | 807 |
| CYP8B1 | 789 |
| CYP17A1 | 777 |
| PRKAG2 | 740 |
| ARNTL | 732 |
| PLPP2 | 694 |
| ECI1 | 669 |
| MED31 | 657 |
| HADHB | 568 |
| FDX2 | 557 |
| ECHS1 | 523 |
| PLEKHA8 | 515 |
| GGT1 | 514 |
| MTM1 | 500 |
| CERS5 | 459 |
| ABHD4 | 422 |
| INPP4A | 400 |
| NR1H2 | 373 |
| HACD1 | 370 |
| PIK3C2A | 365 |
| CYP46A1 | 347 |
| MED8 | 308 |
| ACACA | 236 |
| DGAT1 | 222 |
| TSPO | 220 |
| SACM1L | 218 |
| OXCT1 | 203 |
| TNFAIP8L3 | 182 |
| SLC44A4 | 151 |
| HDAC3 | 84 |
| AKR1C3 | 54 |
| HTD2 | 47 |
| SGPL1 | 10 |
Platelet degranulation
| 804 | |
|---|---|
| set | Platelet degranulation |
| setSize | 103 |
| pANOVA | 1.12e-05 |
| s.dist | 0.251 |
| p.adjustANOVA | 0.000888 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MANF | 14533 |
| SERPING1 | 14532 |
| HSPA5 | 14531 |
| KNG1 | 14503 |
| PLG | 14495 |
| IGF2 | 14477 |
| FGA | 14346 |
| SERPINA3 | 14304 |
| LAMP2 | 14291 |
| TGFB1 | 14241 |
| PCYOX1L | 14197 |
| FLNA | 14081 |
| FGB | 14018 |
| ITIH3 | 13927 |
| ACTN1 | 13824 |
| LHFPL2 | 13786 |
| VEGFB | 13646 |
| A1BG | 13591 |
| BRPF3 | 13542 |
| APP | 13532 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MANF | 14533 |
| SERPING1 | 14532 |
| HSPA5 | 14531 |
| KNG1 | 14503 |
| PLG | 14495 |
| IGF2 | 14477 |
| FGA | 14346 |
| SERPINA3 | 14304 |
| LAMP2 | 14291 |
| TGFB1 | 14241 |
| PCYOX1L | 14197 |
| FLNA | 14081 |
| FGB | 14018 |
| ITIH3 | 13927 |
| ACTN1 | 13824 |
| LHFPL2 | 13786 |
| VEGFB | 13646 |
| A1BG | 13591 |
| BRPF3 | 13542 |
| APP | 13532 |
| ANXA5 | 13476 |
| ALDOA | 13474 |
| APOA1 | 13433 |
| SERPINF2 | 13388 |
| TOR4A | 13305 |
| PDGFB | 13263 |
| TIMP1 | 13158 |
| PFN1 | 13146 |
| SERPINA4 | 12966 |
| HABP4 | 12946 |
| TAGLN2 | 12885 |
| TLN1 | 12872 |
| FGG | 12809 |
| CD63 | 12800 |
| ABCC4 | 12699 |
| FAM3C | 12377 |
| NHLRC2 | 12356 |
| ITIH4 | 12212 |
| WDR1 | 12167 |
| CFL1 | 12075 |
| CYB5R1 | 11951 |
| PROS1 | 11519 |
| THBS1 | 11408 |
| SERPINE1 | 11217 |
| TF | 11111 |
| PSAP | 11023 |
| SOD1 | 10975 |
| APOH | 10937 |
| LEFTY2 | 10803 |
| CLU | 10723 |
| CD109 | 10579 |
| CFD | 10570 |
| TMX3 | 10142 |
| TMSB4X | 10078 |
| CD36 | 9953 |
| ACTN4 | 9828 |
| CALU | 9602 |
| VEGFA | 9433 |
| HRG | 9408 |
| PPIA | 9393 |
| APOOL | 9286 |
| CAP1 | 8634 |
| ORM1 | 8400 |
| VCL | 8357 |
| ENDOD1 | 8089 |
| TEX264 | 7996 |
| GTPBP2 | 7790 |
| CD9 | 7746 |
| SERPINA1 | 7622 |
| FERMT3 | 7573 |
| APLP2 | 7009 |
| LGALS3BP | 6917 |
| FN1 | 6525 |
| TIMP3 | 6229 |
| ALB | 5965 |
| ECM1 | 5858 |
| CHID1 | 5583 |
| PDGFA | 5524 |
| GAS6 | 5226 |
| SCCPDH | 4529 |
| VWF | 3777 |
| SPARC | 3167 |
| SPP2 | 3138 |
| CDC37L1 | 3066 |
| SELENOP | 2773 |
| QSOX1 | 2518 |
| ORM2 | 2502 |
| SYTL4 | 2386 |
| A2M | 2340 |
| PECAM1 | 2152 |
| RARRES2 | 1845 |
| F5 | 1638 |
| VTI1B | 1619 |
| OLA1 | 1578 |
| STXBP2 | 1474 |
| F8 | 1460 |
| ITGA2B | 1391 |
| CALM1 | 1340 |
| TUBA4A | 1335 |
| MAGED2 | 745 |
| TGFB3 | 649 |
| PHACTR2 | 144 |
| AHSG | 62 |
Activation of gene expression by SREBF (SREBP)
| 42 | |
|---|---|
| set | Activation of gene expression by SREBF (SREBP) |
| setSize | 42 |
| pANOVA | 1.16e-05 |
| s.dist | 0.391 |
| p.adjustANOVA | 0.000888 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| HMGCS1 | 14473 |
| SQLE | 14468 |
| IDI1 | 14452 |
| HMGCR | 14408 |
| MVK | 14363 |
| DHCR7 | 14319 |
| SREBF2 | 14223 |
| MVD | 14220 |
| FDFT1 | 14189 |
| LSS | 14165 |
| ELOVL6 | 14093 |
| NCOA6 | 13941 |
| PPARA | 13906 |
| SCD | 13413 |
| GPAM | 13366 |
| FDPS | 12999 |
| CYP51A1 | 12901 |
| TM7SF2 | 12785 |
| ACACB | 11531 |
| MED1 | 11468 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HMGCS1 | 14473 |
| SQLE | 14468 |
| IDI1 | 14452 |
| HMGCR | 14408 |
| MVK | 14363 |
| DHCR7 | 14319 |
| SREBF2 | 14223 |
| MVD | 14220 |
| FDFT1 | 14189 |
| LSS | 14165 |
| ELOVL6 | 14093 |
| NCOA6 | 13941 |
| PPARA | 13906 |
| SCD | 13413 |
| GPAM | 13366 |
| FDPS | 12999 |
| CYP51A1 | 12901 |
| TM7SF2 | 12785 |
| ACACB | 11531 |
| MED1 | 11468 |
| SP1 | 11396 |
| GGPS1 | 10498 |
| SC5D | 10071 |
| NCOA1 | 9914 |
| CHD9 | 9842 |
| NFYB | 9634 |
| HELZ2 | 9086 |
| NCOA2 | 9072 |
| RXRA | 8607 |
| MTF1 | 8354 |
| CREBBP | 8214 |
| SREBF1 | 7517 |
| CARM1 | 6725 |
| PMVK | 6407 |
| NFYA | 5142 |
| SMARCD3 | 4455 |
| TGS1 | 4181 |
| FASN | 3698 |
| TBL1X | 3308 |
| TBL1XR1 | 2795 |
| NFYC | 1395 |
| ACACA | 236 |
Transport of small molecules
| 1302 | |
|---|---|
| set | Transport of small molecules |
| setSize | 535 |
| pANOVA | 1.35e-05 |
| s.dist | 0.111 |
| p.adjustANOVA | 0.00098 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SLC6A12 | 14525 |
| SLC2A1 | 14515 |
| SLC3A2 | 14513 |
| SEL1L | 14508 |
| PCSK9 | 14502 |
| ATP2A2 | 14500 |
| LIPG | 14461 |
| SLC4A2 | 14460 |
| AZGP1 | 14459 |
| SLC5A3 | 14456 |
| SLC17A5 | 14434 |
| APOC3 | 14431 |
| ATP6V0B | 14422 |
| DERL2 | 14399 |
| MAGT1 | 14398 |
| RUNX1 | 14359 |
| SLC33A1 | 14348 |
| STEAP3 | 14327 |
| OS9 | 14320 |
| ATP6V0A1 | 14310 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SLC6A12 | 14525 |
| SLC2A1 | 14515 |
| SLC3A2 | 14513 |
| SEL1L | 14508 |
| PCSK9 | 14502 |
| ATP2A2 | 14500 |
| LIPG | 14461 |
| SLC4A2 | 14460 |
| AZGP1 | 14459 |
| SLC5A3 | 14456 |
| SLC17A5 | 14434 |
| APOC3 | 14431 |
| ATP6V0B | 14422 |
| DERL2 | 14399 |
| MAGT1 | 14398 |
| RUNX1 | 14359 |
| SLC33A1 | 14348 |
| STEAP3 | 14327 |
| OS9 | 14320 |
| ATP6V0A1 | 14310 |
| CLCN7 | 14303 |
| CP | 14292 |
| SLC1A4 | 14285 |
| ATP1B3 | 14249 |
| ATP6V1D | 14228 |
| ATP6V0D1 | 14206 |
| SLC39A7 | 14185 |
| P4HB | 14170 |
| ATP6V0A2 | 14162 |
| AQP3 | 14157 |
| HDLBP | 14154 |
| SLC22A7 | 14131 |
| LRRC8A | 14125 |
| SLC26A1 | 14123 |
| CES3 | 14110 |
| SLC2A2 | 14109 |
| SLC6A6 | 14092 |
| ABCB1 | 14065 |
| SLC30A7 | 14058 |
| NEDD4L | 14037 |
| ABCB4 | 14032 |
| SLC7A6 | 14024 |
| CYGB | 14010 |
| ATP1A1 | 13992 |
| SLC12A7 | 13978 |
| LSR | 13970 |
| ATP9A | 13965 |
| SLC39A14 | 13945 |
| ATP8B2 | 13934 |
| ATP13A1 | 13918 |
| VCP | 13902 |
| SLC22A15 | 13900 |
| FTL | 13872 |
| FURIN | 13851 |
| NIPA2 | 13823 |
| SLC35C1 | 13821 |
| PSMF1 | 13810 |
| SGK3 | 13801 |
| SLC5A9 | 13788 |
| TFRC | 13755 |
| RNF5 | 13745 |
| SLC39A10 | 13739 |
| ATP1B1 | 13734 |
| ATP6V0E1 | 13731 |
| SLC38A4 | 13723 |
| ABCC2 | 13713 |
| SLC6A2 | 13711 |
| PEX19 | 13704 |
| MCOLN1 | 13693 |
| TFR2 | 13670 |
| SGK2 | 13618 |
| SLC13A5 | 13529 |
| LCAT | 13483 |
| PSME4 | 13450 |
| APOA1 | 13433 |
| CLTA | 13432 |
| PSMD2 | 13423 |
| SLC6A9 | 13399 |
| DERL1 | 13398 |
| SOAT2 | 13385 |
| SLC30A1 | 13381 |
| SLC9A1 | 13358 |
| ANGPTL4 | 13342 |
| SLC2A8 | 13319 |
| RNF185 | 13291 |
| SLCO2B1 | 13235 |
| APOA2 | 13191 |
| FKBP1B | 13183 |
| SLC44A2 | 13182 |
| SLC30A10 | 13175 |
| SCNN1A | 13173 |
| CLCN3 | 13163 |
| ATP6V1E1 | 13114 |
| SLC13A3 | 13083 |
| ABCD1 | 13062 |
| ATP6AP1 | 13046 |
| CUTC | 13036 |
| NCEH1 | 13032 |
| SLC12A6 | 13027 |
| SLC39A4 | 13020 |
| CLTC | 13017 |
| NPC2 | 12991 |
| LIPC | 12986 |
| GNG10 | 12977 |
| ATP2B4 | 12954 |
| SLC25A22 | 12936 |
| ERLEC1 | 12918 |
| SLC31A1 | 12803 |
| SLC38A1 | 12783 |
| ATP6V0C | 12764 |
| SLC36A1 | 12750 |
| ATP7B | 12740 |
| CTNS | 12728 |
| ABCC4 | 12699 |
| MYLIP | 12695 |
| ACO1 | 12690 |
| ABCG5 | 12609 |
| RHBG | 12570 |
| SLC1A5 | 12542 |
| ADD1 | 12538 |
| MBTPS1 | 12523 |
| PSMD6 | 12502 |
| ABCC1 | 12501 |
| NPC1 | 12486 |
| LETM1 | 12482 |
| ATP6V1C2 | 12453 |
| SCNN1D | 12435 |
| AFG3L2 | 12427 |
| ABCF1 | 12365 |
| SLC16A10 | 12348 |
| FXYD2 | 12339 |
| ANO6 | 12256 |
| PSMA2 | 12203 |
| SLCO4A1 | 12084 |
| TRPM7 | 12063 |
| SLC17A1 | 12062 |
| PSMA1 | 12052 |
| SLC22A3 | 12047 |
| ALAD | 12045 |
| ADCY7 | 12040 |
| SLC26A11 | 12012 |
| HFE | 11997 |
| SLC5A6 | 11982 |
| CYB5R1 | 11951 |
| ABCC3 | 11944 |
| MTTP | 11924 |
| SLC7A2 | 11923 |
| SLC29A1 | 11917 |
| SLC7A3 | 11852 |
| CLCN4 | 11792 |
| ATP6V1B2 | 11744 |
| GNG4 | 11731 |
| PSMC1 | 11724 |
| RAF1 | 11708 |
| SLC7A11 | 11686 |
| PSMD3 | 11655 |
| YME1L1 | 11621 |
| SLC7A5 | 11592 |
| PSME2 | 11555 |
| BEST4 | 11546 |
| ATP10A | 11471 |
| ABCC10 | 11451 |
| AQP8 | 11449 |
| TRPM4 | 11442 |
| CREB3L3 | 11433 |
| ATP8A1 | 11425 |
| ASIC1 | 11407 |
| FTH1 | 11406 |
| PSMD14 | 11371 |
| SLC38A2 | 11345 |
| OSTM1 | 11289 |
| ATP6V1G1 | 11283 |
| PSMD1 | 11280 |
| ATP13A2 | 11229 |
| TTYH3 | 11226 |
| ATP2B1 | 11220 |
| MICU2 | 11176 |
| SLC12A2 | 11147 |
| TF | 11111 |
| PMPCB | 11098 |
| ABCA2 | 11066 |
| EIF2S1 | 10961 |
| FLVCR1 | 10949 |
| ANGPTL8 | 10936 |
| ARL2 | 10857 |
| ADD3 | 10801 |
| ATP6V0E2 | 10798 |
| SLCO4C1 | 10785 |
| FBXL5 | 10775 |
| SLC9A6 | 10721 |
| SLC7A10 | 10715 |
| UBA52 | 10707 |
| LMF1 | 10661 |
| SLC16A3 | 10630 |
| SLC35B4 | 10583 |
| FGF21 | 10580 |
| CIDEC | 10542 |
| SLC1A2 | 10514 |
| ATP6V1C1 | 10444 |
| PSMB9 | 10430 |
| SLC27A1 | 10421 |
| ABCC5 | 10405 |
| PHB | 10399 |
| CLCN5 | 10384 |
| BSG | 10339 |
| PSMB6 | 10326 |
| PLTP | 10314 |
| PSMC6 | 10307 |
| NIPAL2 | 10281 |
| STEAP2 | 10271 |
| ERLIN2 | 10235 |
| PSMC4 | 10196 |
| SLC35B3 | 10191 |
| SLC39A1 | 10116 |
| SLC29A2 | 10107 |
| PCSK6 | 10075 |
| HMOX2 | 10061 |
| LRRC8E | 10038 |
| APOC2 | 9992 |
| MICU3 | 9966 |
| SLC41A2 | 9890 |
| SLC2A13 | 9877 |
| LDLR | 9855 |
| SLC24A1 | 9854 |
| PSMD9 | 9853 |
| AP2M1 | 9787 |
| PSMD5 | 9676 |
| SLC35D2 | 9628 |
| NIPA1 | 9625 |
| GNB2 | 9583 |
| SLCO2A1 | 9440 |
| EIF2S2 | 9437 |
| SLC35A3 | 9426 |
| ABCB10 | 9418 |
| AQP7 | 9413 |
| PSMD7 | 9371 |
| ATP6V1H | 9358 |
| PSMD10 | 9356 |
| BEST1 | 9355 |
| SLC34A3 | 9335 |
| PSMB7 | 9253 |
| SLC30A3 | 9248 |
| TPCN2 | 9157 |
| ATP9B | 9145 |
| ADCY1 | 9122 |
| ASPH | 9100 |
| TSC22D3 | 9049 |
| UBB | 9013 |
| PSMA4 | 8902 |
| NR1H3 | 8878 |
| SLC44A3 | 8864 |
| CUL1 | 8725 |
| HMOX1 | 8715 |
| CLCN2 | 8698 |
| PSMD4 | 8670 |
| CAMK2A | 8669 |
| LCN2 | 8658 |
| AQP11 | 8655 |
| PSMC5 | 8646 |
| ATP6V1B1 | 8635 |
| APOF | 8633 |
| RAB11A | 8597 |
| SLC8B1 | 8584 |
| SLC38A5 | 8563 |
| SLC2A14 | 8550 |
| KCNJ11 | 8545 |
| ATP2A1 | 8492 |
| NIPAL3 | 8482 |
| PARL | 8480 |
| SLC25A5 | 8466 |
| TTYH1 | 8417 |
| GNG7 | 8395 |
| SCARB1 | 8356 |
| SLC2A11 | 8353 |
| SLCO1B3 | 8303 |
| GLRX3 | 8244 |
| PSMD12 | 8163 |
| ADCY9 | 8130 |
| ABCC6 | 8124 |
| SLC2A10 | 8109 |
| SLC30A6 | 8074 |
| PSME3 | 8052 |
| ATP6V1A | 7965 |
| SLC30A5 | 7959 |
| SLC25A6 | 7878 |
| GNG5 | 7830 |
| APOA5 | 7816 |
| ATP1B2 | 7805 |
| APOE | 7759 |
| EIF2S3 | 7757 |
| SLC16A1 | 7693 |
| LCN12 | 7637 |
| UNC80 | 7499 |
| TTYH2 | 7495 |
| SLC35A1 | 7418 |
| AP2A2 | 7391 |
| ANO9 | 7334 |
| SLC9A4 | 7317 |
| SLC39A5 | 7315 |
| SLC22A17 | 7295 |
| LMF2 | 7243 |
| ABCA5 | 7239 |
| LIPA | 7201 |
| LRRC8B | 7129 |
| SLC25A26 | 7125 |
| MBTPS2 | 7019 |
| SLC15A1 | 6960 |
| SLC43A2 | 6891 |
| TRPC1 | 6877 |
| SLC35D1 | 6862 |
| PEX3 | 6860 |
| WNK2 | 6844 |
| ADD2 | 6840 |
| GNB1 | 6796 |
| MMGT1 | 6784 |
| SLC38A3 | 6758 |
| SLC11A2 | 6749 |
| SLC11A1 | 6739 |
| SLC5A2 | 6735 |
| SLC25A4 | 6719 |
| CYB5R4 | 6715 |
| SLC7A1 | 6668 |
| PCSK5 | 6597 |
| SEM1 | 6566 |
| SLC26A6 | 6561 |
| PDZD11 | 6494 |
| PSMA3 | 6422 |
| TRPM6 | 6362 |
| AHCYL2 | 6312 |
| HBA1 | 6302 |
| LRRC8D | 6262 |
| SLC1A7 | 6227 |
| ANO7 | 6199 |
| SAR1B | 6198 |
| ERLIN1 | 6181 |
| APOB | 6172 |
| SLC39A3 | 6110 |
| CLCN6 | 6094 |
| PSMD8 | 6091 |
| AP2S1 | 6073 |
| SLC29A4 | 6038 |
| ABCC9 | 6037 |
| MICU1 | 5968 |
| VDAC2 | 5966 |
| ALB | 5965 |
| SLC4A7 | 5963 |
| FXYD1 | 5919 |
| ADCY6 | 5862 |
| SLC9A7 | 5856 |
| SPG7 | 5853 |
| ABCA3 | 5842 |
| DMTN | 5795 |
| RPS27A | 5776 |
| VLDLR | 5770 |
| STOML2 | 5739 |
| SLC22A4 | 5732 |
| SLC28A2 | 5722 |
| SLC7A7 | 5704 |
| SLC4A3 | 5700 |
| ABCG8 | 5687 |
| SLC35A2 | 5685 |
| PSMA5 | 5657 |
| SLC24A4 | 5578 |
| SLC36A4 | 5557 |
| SLC44A5 | 5540 |
| CETP | 5470 |
| SLC28A1 | 5420 |
| SLC20A2 | 5400 |
| SOAT1 | 5394 |
| PSMD13 | 5353 |
| TRPC4AP | 5347 |
| SLC22A1 | 5220 |
| SLC22A16 | 5211 |
| ABCB6 | 5157 |
| PHB2 | 5140 |
| MRS2 | 5059 |
| ATP11B | 5015 |
| SLC26A2 | 4985 |
| SMDT1 | 4971 |
| PSMC2 | 4948 |
| ANO10 | 4894 |
| SLC9A8 | 4887 |
| SLC6A11 | 4870 |
| PSME1 | 4861 |
| SLC5A11 | 4837 |
| PMPCA | 4832 |
| ABCA1 | 4752 |
| RYR3 | 4725 |
| ABCG2 | 4707 |
| SLC15A4 | 4647 |
| ANKH | 4588 |
| IREB2 | 4556 |
| TRPV4 | 4517 |
| SLC43A1 | 4501 |
| SLC40A1 | 4248 |
| SLC44A1 | 4205 |
| CAMK2G | 4176 |
| SLC47A1 | 4136 |
| ATP7A | 4123 |
| SLC7A9 | 4084 |
| SLCO1A2 | 4048 |
| SLC41A1 | 3998 |
| SLC22A5 | 3989 |
| AP2B1 | 3955 |
| ATP8B1 | 3930 |
| PSMB3 | 3928 |
| ARL2BP | 3919 |
| AP2A1 | 3903 |
| ABCA10 | 3897 |
| SLC2A9 | 3896 |
| GNB4 | 3781 |
| ATP11C | 3691 |
| PSMB2 | 3678 |
| WNK4 | 3620 |
| SLC3A1 | 3595 |
| APOBR | 3591 |
| SLC30A2 | 3567 |
| SLC4A5 | 3549 |
| CLIC2 | 3497 |
| ASIC3 | 3495 |
| ATP1A3 | 3489 |
| SLC20A1 | 3471 |
| PRKACA | 3407 |
| CAND1 | 3381 |
| CAMK2D | 3358 |
| ATP10D | 3294 |
| SLC12A4 | 3276 |
| SLC9B2 | 3192 |
| CYB5RL | 3125 |
| SLC2A3 | 3116 |
| STOM | 3093 |
| PSMC3 | 3070 |
| SLC50A1 | 3058 |
| SLC1A6 | 2942 |
| TRPV3 | 2941 |
| ATP11A | 2935 |
| PRKACB | 2885 |
| SLC9B1 | 2876 |
| WNK3 | 2842 |
| SLC35B2 | 2785 |
| ABCB9 | 2771 |
| ABCA7 | 2604 |
| ATP2B2 | 2557 |
| TUSC3 | 2465 |
| ABCC11 | 2434 |
| LDLRAP1 | 2433 |
| SLC25A29 | 2413 |
| ATP8B3 | 2356 |
| A2M | 2340 |
| SLC15A2 | 2338 |
| PSMB4 | 2330 |
| SLC2A6 | 2245 |
| SLC27A4 | 2241 |
| TPCN1 | 2232 |
| LRRC8C | 2208 |
| SLC25A10 | 2172 |
| ABCA6 | 2114 |
| PRKAR1B | 2113 |
| VDAC1 | 2092 |
| GNB3 | 2063 |
| PSMB1 | 2062 |
| SLC12A5 | 2048 |
| SLC2A4 | 2019 |
| SLC9A5 | 2001 |
| SLC39A8 | 1929 |
| PSMA7 | 1820 |
| SLC39A6 | 1807 |
| AMN | 1802 |
| CYBRD1 | 1784 |
| ATP6V1F | 1771 |
| PRKAR2A | 1753 |
| SLC14A2 | 1727 |
| SLC6A20 | 1719 |
| SLC46A1 | 1702 |
| SGK1 | 1698 |
| CUBN | 1678 |
| SLC4A8 | 1616 |
| MCUB | 1610 |
| WWP1 | 1572 |
| UBC | 1551 |
| SLC45A3 | 1548 |
| CYB5R2 | 1534 |
| ATP6V0D2 | 1494 |
| APOC1 | 1491 |
| PSMB5 | 1484 |
| LCN15 | 1482 |
| ATP2C1 | 1467 |
| RAB11FIP2 | 1442 |
| UNC79 | 1413 |
| GNB5 | 1388 |
| SLC6A14 | 1374 |
| ATP6V1G2 | 1360 |
| ADCY2 | 1356 |
| CALM1 | 1340 |
| ANO3 | 1301 |
| ATP10B | 1240 |
| NEDD8 | 1131 |
| SKP1 | 1117 |
| SLC16A7 | 1113 |
| ATP6V1E2 | 1090 |
| AQP6 | 1080 |
| WNK1 | 1076 |
| SLC29A3 | 930 |
| GNAS | 900 |
| TRPV1 | 891 |
| PSMD11 | 879 |
| MCU | 850 |
| PSMB10 | 838 |
| ABCD3 | 821 |
| ATP1A4 | 810 |
| MFSD4B | 751 |
| AKAP1 | 674 |
| ABCA9 | 670 |
| BMP1 | 626 |
| ZDHHC8 | 577 |
| VDAC3 | 561 |
| SLC22A18 | 512 |
| SLC17A7 | 487 |
| APOA4 | 444 |
| RSC1A1 | 387 |
| NR1H2 | 373 |
| ANO8 | 350 |
| TCIRG1 | 348 |
| SLC4A1 | 280 |
| ABCA4 | 271 |
| PSMA6 | 261 |
| SLC26A3 | 165 |
| NIPAL1 | 164 |
| SLC44A4 | 151 |
| ABCB8 | 138 |
| SLC22A11 | 97 |
| TRPV2 | 69 |
| ABCB7 | 64 |
| MYO5B | 11 |
| PRKAR1A | 6 |
Regulation of Complement cascade
| 946 | |
|---|---|
| set | Regulation of Complement cascade |
| setSize | 30 |
| pANOVA | 1.5e-05 |
| s.dist | 0.457 |
| p.adjustANOVA | 0.00103 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SERPING1 | 14532 |
| C1S | 14430 |
| C3 | 14417 |
| CFB | 14394 |
| C4A | 14381 |
| C8B | 14372 |
| C4B | 14173 |
| C8A | 14042 |
| C4BPB | 14006 |
| C5 | 14003 |
| C1R | 13954 |
| CD55 | 13575 |
| VTN | 13246 |
| CFI | 13206 |
| C5AR1 | 12862 |
| C6 | 12636 |
| PROS1 | 11519 |
| CLU | 10723 |
| C4BPA | 9865 |
| CD46 | 9531 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SERPING1 | 14532 |
| C1S | 14430 |
| C3 | 14417 |
| CFB | 14394 |
| C4A | 14381 |
| C8B | 14372 |
| C4B | 14173 |
| C8A | 14042 |
| C4BPB | 14006 |
| C5 | 14003 |
| C1R | 13954 |
| CD55 | 13575 |
| VTN | 13246 |
| CFI | 13206 |
| C5AR1 | 12862 |
| C6 | 12636 |
| PROS1 | 11519 |
| CLU | 10723 |
| C4BPA | 9865 |
| CD46 | 9531 |
| C7 | 9004 |
| CPB2 | 8234 |
| C2 | 8098 |
| CPN1 | 7658 |
| CD59 | 6818 |
| C5AR2 | 6671 |
| C8G | 4585 |
| F2 | 1246 |
| CD19 | 954 |
| CPN2 | 221 |
Hemostasis
| 480 | |
|---|---|
| set | Hemostasis |
| setSize | 409 |
| pANOVA | 2.39e-05 |
| s.dist | 0.122 |
| p.adjustANOVA | 0.00154 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MANF | 14533 |
| SERPING1 | 14532 |
| HSPA5 | 14531 |
| SLC3A2 | 14513 |
| KNG1 | 14503 |
| ATP2A2 | 14500 |
| PLG | 14495 |
| IGF2 | 14477 |
| ARRB1 | 14420 |
| FGA | 14346 |
| MAFK | 14318 |
| SERPINA3 | 14304 |
| CEACAM1 | 14302 |
| MAFG | 14298 |
| LAMP2 | 14291 |
| ATP1B3 | 14249 |
| TGFB1 | 14241 |
| BCAR1 | 14233 |
| SHC1 | 14209 |
| PCYOX1L | 14197 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MANF | 14533 |
| SERPING1 | 14532 |
| HSPA5 | 14531 |
| SLC3A2 | 14513 |
| KNG1 | 14503 |
| ATP2A2 | 14500 |
| PLG | 14495 |
| IGF2 | 14477 |
| ARRB1 | 14420 |
| FGA | 14346 |
| MAFK | 14318 |
| SERPINA3 | 14304 |
| CEACAM1 | 14302 |
| MAFG | 14298 |
| LAMP2 | 14291 |
| ATP1B3 | 14249 |
| TGFB1 | 14241 |
| BCAR1 | 14233 |
| SHC1 | 14209 |
| PCYOX1L | 14197 |
| KCNMB3 | 14128 |
| P2RX1 | 14116 |
| DAGLA | 14113 |
| FLNA | 14081 |
| SLC7A6 | 14024 |
| FGB | 14018 |
| CBX5 | 14012 |
| ITIH3 | 13927 |
| SERPINB8 | 13922 |
| CABLES1 | 13825 |
| ACTN1 | 13824 |
| LHFPL2 | 13786 |
| TNFRSF10B | 13770 |
| KIF5A | 13752 |
| ATP1B1 | 13734 |
| GNA13 | 13689 |
| SERPINC1 | 13683 |
| PRKCZ | 13676 |
| ESAM | 13675 |
| VEGFB | 13646 |
| A1BG | 13591 |
| F11R | 13568 |
| SPN | 13546 |
| BRPF3 | 13542 |
| APP | 13532 |
| SERPINA5 | 13513 |
| ITGA10 | 13478 |
| ANXA5 | 13476 |
| ALDOA | 13474 |
| APOA1 | 13433 |
| ADRA2C | 13422 |
| SERPINF2 | 13388 |
| GATA4 | 13306 |
| TOR4A | 13305 |
| KIF22 | 13293 |
| PDGFB | 13263 |
| CABLES2 | 13226 |
| KIF3B | 13207 |
| ABHD12 | 13159 |
| TIMP1 | 13158 |
| PFN1 | 13146 |
| CD99L2 | 13134 |
| GNA12 | 13131 |
| S100A10 | 13095 |
| LCK | 13069 |
| DGKZ | 12992 |
| ITGA2 | 12988 |
| GNG10 | 12977 |
| SERPINA4 | 12966 |
| ATP2B4 | 12954 |
| HABP4 | 12946 |
| PAFAH2 | 12920 |
| TAGLN2 | 12885 |
| TLN1 | 12872 |
| PROC | 12863 |
| FGG | 12809 |
| CD63 | 12800 |
| SERPIND1 | 12796 |
| KIF20B | 12774 |
| ITPR3 | 12768 |
| ABCC4 | 12699 |
| MAPK3 | 12684 |
| THPO | 12650 |
| MFN2 | 12586 |
| DGKE | 12576 |
| KIF11 | 12553 |
| KIFAP3 | 12544 |
| EHD1 | 12536 |
| PTPN6 | 12513 |
| GNA11 | 12425 |
| MAFF | 12413 |
| ITGB2 | 12388 |
| FAM3C | 12377 |
| SIN3A | 12373 |
| NHLRC2 | 12356 |
| F13B | 12289 |
| KIF2A | 12231 |
| ITIH4 | 12212 |
| F12 | 12198 |
| ZFPM1 | 12174 |
| WDR1 | 12167 |
| PPP2R5A | 12088 |
| CFL1 | 12075 |
| F7 | 12069 |
| ITGAL | 12056 |
| KIF23 | 12032 |
| CYB5R1 | 11951 |
| CRK | 11901 |
| PRKCD | 11872 |
| KIF12 | 11816 |
| GNG4 | 11731 |
| ANXA2 | 11716 |
| RAF1 | 11708 |
| SLC7A11 | 11686 |
| PSG2 | 11682 |
| HRAS | 11673 |
| NFE2 | 11657 |
| CD47 | 11617 |
| PRKCE | 11606 |
| SLC7A5 | 11592 |
| CD58 | 11554 |
| RHOB | 11537 |
| KIF4A | 11524 |
| PROS1 | 11519 |
| KIF15 | 11499 |
| KIF16B | 11491 |
| RAD51C | 11490 |
| PDE9A | 11485 |
| KIF5B | 11419 |
| THBS1 | 11408 |
| RAB5A | 11392 |
| KIF2C | 11386 |
| KIF20A | 11285 |
| ATP2B1 | 11220 |
| SERPINE1 | 11217 |
| RHOA | 11182 |
| KIF13B | 11172 |
| TF | 11111 |
| PSAP | 11023 |
| RACGAP1 | 10990 |
| SOD1 | 10975 |
| APOH | 10937 |
| MIF | 10935 |
| PPP2CA | 10917 |
| F10 | 10888 |
| DGKA | 10844 |
| PPP2R5B | 10834 |
| LEFTY2 | 10803 |
| SERPINE2 | 10796 |
| AAMP | 10725 |
| CLU | 10723 |
| SLC7A10 | 10715 |
| MAPK1 | 10705 |
| SLC16A3 | 10630 |
| CD109 | 10579 |
| CFD | 10570 |
| TNFRSF10D | 10566 |
| CENPE | 10538 |
| NOS3 | 10359 |
| BSG | 10339 |
| CAPZA1 | 10272 |
| ORAI2 | 10259 |
| P2RX4 | 10229 |
| TMX3 | 10142 |
| SH2B3 | 10091 |
| TMSB4X | 10078 |
| PPP2R1A | 10064 |
| DGKK | 9983 |
| CD36 | 9953 |
| KIF18A | 9884 |
| VAV3 | 9861 |
| RBSN | 9844 |
| ACTN4 | 9828 |
| IRF1 | 9820 |
| GNAI3 | 9793 |
| GPC1 | 9776 |
| ITGA1 | 9740 |
| CARMIL1 | 9621 |
| PPP2CB | 9606 |
| CALU | 9602 |
| GNB2 | 9583 |
| VEGFA | 9433 |
| ITPK1 | 9412 |
| HRG | 9408 |
| PPIA | 9393 |
| TNFRSF10A | 9306 |
| APOOL | 9286 |
| KIF18B | 9265 |
| PIK3R1 | 9259 |
| PTK2 | 9198 |
| LRP8 | 9195 |
| F11 | 9173 |
| ITPR1 | 9146 |
| ITGAV | 9120 |
| PLAT | 9105 |
| VPS45 | 9030 |
| MERTK | 9003 |
| PDE11A | 8972 |
| PPIL2 | 8970 |
| ITGB1 | 8760 |
| PPP2R1B | 8759 |
| KLC1 | 8755 |
| TSPAN7 | 8731 |
| CSK | 8692 |
| CAP1 | 8634 |
| DOCK5 | 8523 |
| PLAUR | 8513 |
| DAGLB | 8497 |
| ATP2A1 | 8492 |
| GRB7 | 8477 |
| ORM1 | 8400 |
| GNG7 | 8395 |
| KIF9 | 8378 |
| VCL | 8357 |
| PICK1 | 8308 |
| GNAI2 | 8246 |
| ENDOD1 | 8089 |
| SDC3 | 8055 |
| MFN1 | 8050 |
| KDM1A | 8018 |
| TEX264 | 7996 |
| PLCG2 | 7942 |
| RAD51B | 7901 |
| GNG5 | 7830 |
| LAT | 7813 |
| CDK2 | 7809 |
| ATP1B2 | 7805 |
| GTPBP2 | 7790 |
| CD9 | 7746 |
| KIF21A | 7701 |
| SLC16A1 | 7693 |
| JAM3 | 7676 |
| SH2B1 | 7640 |
| SERPINA1 | 7622 |
| FERMT3 | 7573 |
| SRC | 7516 |
| SIRPA | 7474 |
| INPP5D | 7467 |
| KLC4 | 7401 |
| STXBP3 | 7400 |
| RCOR1 | 7376 |
| F2R | 7320 |
| DOCK7 | 7277 |
| KLC2 | 7112 |
| APLP2 | 7009 |
| STIM1 | 7007 |
| LGALS3BP | 6917 |
| PTPN1 | 6909 |
| RAP1B | 6830 |
| ARRB2 | 6824 |
| GNB1 | 6796 |
| DOCK1 | 6760 |
| HMG20B | 6676 |
| KIFC2 | 6618 |
| FN1 | 6525 |
| KIF3A | 6347 |
| GRB2 | 6346 |
| LYN | 6328 |
| GLG1 | 6233 |
| TIMP3 | 6229 |
| KCNMB4 | 6197 |
| APOB | 6172 |
| PLAU | 6169 |
| AKT1 | 6160 |
| KLC3 | 5986 |
| ALB | 5965 |
| CD99 | 5861 |
| ECM1 | 5858 |
| PIK3CA | 5849 |
| PROCR | 5763 |
| RHOG | 5747 |
| SLC7A7 | 5704 |
| EHD2 | 5680 |
| JAK2 | 5664 |
| KIF21B | 5629 |
| CHID1 | 5583 |
| HDAC1 | 5563 |
| AKAP10 | 5536 |
| PDGFA | 5524 |
| EHD3 | 5520 |
| VAV2 | 5425 |
| PIK3CB | 5379 |
| KIF1B | 5362 |
| ANGPT2 | 5309 |
| DGKD | 5302 |
| PPP2R5C | 5293 |
| WEE1 | 5244 |
| GAS6 | 5226 |
| AK3 | 5212 |
| F2RL3 | 5187 |
| GNAI1 | 5167 |
| SERPINB6 | 5125 |
| PLCG1 | 4855 |
| GATA6 | 4816 |
| PIK3R3 | 4734 |
| PRCP | 4730 |
| PRKCA | 4709 |
| SCCPDH | 4529 |
| CDC42 | 4489 |
| KIF1C | 4483 |
| NRAS | 4465 |
| SDC4 | 4450 |
| MAPK14 | 4391 |
| PPP2R5D | 4385 |
| KIF5C | 4382 |
| ITPR2 | 4366 |
| KRAS | 4210 |
| SDC1 | 4201 |
| TP53 | 4144 |
| SLC7A9 | 4084 |
| DGKQ | 4067 |
| DOCK8 | 4066 |
| ITGA6 | 4010 |
| HBG2 | 4007 |
| ABL1 | 3944 |
| FYN | 3783 |
| GNB4 | 3781 |
| VWF | 3777 |
| ITGAX | 3756 |
| TFPI | 3729 |
| KIF3C | 3639 |
| DOCK9 | 3436 |
| PRKACA | 3407 |
| ITGA3 | 3390 |
| DGKG | 3322 |
| KCNMB1 | 3258 |
| F3 | 3237 |
| PRKCH | 3185 |
| SPARC | 3167 |
| CAPZA2 | 3143 |
| SPP2 | 3138 |
| CDC37L1 | 3066 |
| KIF6 | 2972 |
| PRKACB | 2885 |
| ORAI1 | 2851 |
| HBE1 | 2816 |
| KIF26B | 2804 |
| SELENOP | 2773 |
| ZFPM2 | 2765 |
| PIK3R2 | 2728 |
| CDK5 | 2721 |
| KLKB1 | 2707 |
| EPCAM | 2699 |
| YES1 | 2690 |
| JMJD1C | 2636 |
| GATA2 | 2587 |
| ATP2B2 | 2557 |
| P2RX5 | 2533 |
| QSOX1 | 2518 |
| ORM2 | 2502 |
| SYTL4 | 2386 |
| DOCK4 | 2380 |
| CAPZB | 2376 |
| KIF27 | 2370 |
| A2M | 2340 |
| CD74 | 2282 |
| SH2B2 | 2259 |
| TBXA2R | 2235 |
| PHF21A | 2202 |
| PECAM1 | 2152 |
| JAML | 2138 |
| PRKAR1B | 2113 |
| GNB3 | 2063 |
| CEACAM5 | 1981 |
| SOS1 | 1928 |
| ABHD6 | 1891 |
| RARRES2 | 1845 |
| L1CAM | 1841 |
| YWHAZ | 1810 |
| PTPN11 | 1770 |
| PRKAR2A | 1753 |
| F5 | 1638 |
| VTI1B | 1619 |
| GNAQ | 1588 |
| DGKH | 1586 |
| OLA1 | 1578 |
| STXBP2 | 1474 |
| F8 | 1460 |
| NOS1 | 1403 |
| ITGA2B | 1391 |
| GNB5 | 1388 |
| C1QBP | 1380 |
| KIFC1 | 1342 |
| CALM1 | 1340 |
| TUBA4A | 1335 |
| DOCK6 | 1298 |
| F2 | 1246 |
| ITGA5 | 1149 |
| STX4 | 995 |
| MICAL1 | 991 |
| GNAS | 900 |
| RAPGEF4 | 863 |
| PDPK1 | 782 |
| FCER1G | 746 |
| MAGED2 | 745 |
| HDAC2 | 693 |
| IRF2 | 690 |
| AKAP1 | 674 |
| TGFB3 | 649 |
| JAM2 | 625 |
| GRB14 | 608 |
| RAP1A | 604 |
| PPP2R5E | 554 |
| SDC2 | 289 |
| PHACTR2 | 144 |
| CXADR | 136 |
| RAC1 | 95 |
| AHSG | 62 |
| PRKAR1A | 6 |
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
| 673 | |
|---|---|
| set | N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
| setSize | 34 |
| pANOVA | 2.46e-05 |
| s.dist | 0.418 |
| p.adjustANOVA | 0.00154 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CALR | 14529 |
| SEL1L | 14508 |
| SYVN1 | 14485 |
| EDEM1 | 14479 |
| CANX | 14462 |
| PDIA3 | 14454 |
| DERL2 | 14399 |
| OS9 | 14320 |
| UGGT1 | 14270 |
| MLEC | 14193 |
| VCP | 13902 |
| RNF5 | 13745 |
| DERL1 | 13398 |
| RNF185 | 13291 |
| RNF103 | 12848 |
| PRKCSH | 12463 |
| ENGASE | 12309 |
| PSMC1 | 11724 |
| EDEM2 | 11628 |
| UBXN1 | 11466 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CALR | 14529 |
| SEL1L | 14508 |
| SYVN1 | 14485 |
| EDEM1 | 14479 |
| CANX | 14462 |
| PDIA3 | 14454 |
| DERL2 | 14399 |
| OS9 | 14320 |
| UGGT1 | 14270 |
| MLEC | 14193 |
| VCP | 13902 |
| RNF5 | 13745 |
| DERL1 | 13398 |
| RNF185 | 13291 |
| RNF103 | 12848 |
| PRKCSH | 12463 |
| ENGASE | 12309 |
| PSMC1 | 11724 |
| EDEM2 | 11628 |
| UBXN1 | 11466 |
| UBA52 | 10707 |
| UBB | 9013 |
| MAN1B1 | 7534 |
| RNF139 | 6382 |
| RAD23B | 6054 |
| NGLY1 | 6049 |
| RPS27A | 5776 |
| AMFR | 5612 |
| GANAB | 5417 |
| MOGS | 4728 |
| EDEM3 | 3904 |
| TRIM13 | 3695 |
| UGGT2 | 2839 |
| UBC | 1551 |
Neutrophil degranulation
| 715 | |
|---|---|
| set | Neutrophil degranulation |
| setSize | 352 |
| pANOVA | 3.51e-05 |
| s.dist | 0.129 |
| p.adjustANOVA | 0.0021 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| DNAJC3 | 14516 |
| C3 | 14417 |
| MAGT1 | 14398 |
| CNN2 | 14383 |
| ERP44 | 14364 |
| LAMP1 | 14314 |
| ATP6V0A1 | 14310 |
| SERPINA3 | 14304 |
| CEACAM1 | 14302 |
| LAMP2 | 14291 |
| ARSB | 14246 |
| GGH | 14243 |
| LGALS3 | 14229 |
| ATP6V1D | 14228 |
| MLEC | 14193 |
| PLD1 | 14191 |
| S100A11 | 14143 |
| P2RX1 | 14116 |
| GCA | 14108 |
| BRI3 | 14094 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| DNAJC3 | 14516 |
| C3 | 14417 |
| MAGT1 | 14398 |
| CNN2 | 14383 |
| ERP44 | 14364 |
| LAMP1 | 14314 |
| ATP6V0A1 | 14310 |
| SERPINA3 | 14304 |
| CEACAM1 | 14302 |
| LAMP2 | 14291 |
| ARSB | 14246 |
| GGH | 14243 |
| LGALS3 | 14229 |
| ATP6V1D | 14228 |
| MLEC | 14193 |
| PLD1 | 14191 |
| S100A11 | 14143 |
| P2RX1 | 14116 |
| GCA | 14108 |
| BRI3 | 14094 |
| GNS | 14052 |
| PNP | 14046 |
| NDUFC2 | 14038 |
| CYSTM1 | 13982 |
| NEU1 | 13953 |
| NHLRC3 | 13928 |
| VCP | 13902 |
| FTL | 13872 |
| PYGB | 13867 |
| ASAH1 | 13777 |
| SURF4 | 13688 |
| TOLLIP | 13662 |
| IGF2R | 13604 |
| FUCA2 | 13600 |
| A1BG | 13591 |
| DNAJC5 | 13582 |
| CD55 | 13575 |
| TMBIM1 | 13533 |
| ALDOA | 13474 |
| HEXB | 13459 |
| DDX3X | 13448 |
| CD14 | 13442 |
| RAB37 | 13426 |
| PSMD2 | 13423 |
| DDOST | 13410 |
| CDK13 | 13387 |
| KCMF1 | 13357 |
| KPNB1 | 13324 |
| UBR4 | 13266 |
| DSN1 | 13258 |
| ATAD3B | 13239 |
| PYCARD | 13221 |
| GALNS | 13205 |
| SLC44A2 | 13182 |
| CTSA | 13149 |
| ALDH3B1 | 13143 |
| PRDX4 | 13105 |
| NPC2 | 12991 |
| TUBB4B | 12934 |
| PGAM1 | 12932 |
| RAP2B | 12931 |
| CDA | 12891 |
| HP | 12884 |
| LRG1 | 12875 |
| C5AR1 | 12862 |
| SYNGR1 | 12842 |
| TMC6 | 12813 |
| CD63 | 12800 |
| PTPRJ | 12791 |
| PDXK | 12784 |
| ATP6V0C | 12764 |
| DEGS1 | 12708 |
| PTPN6 | 12513 |
| PSMD6 | 12502 |
| SRP14 | 12470 |
| MVP | 12465 |
| CCT2 | 12444 |
| ARL8A | 12434 |
| ITGB2 | 12388 |
| DOK3 | 12363 |
| CD68 | 12316 |
| CAPN1 | 12305 |
| ANO6 | 12256 |
| RAB7A | 12220 |
| DIAPH1 | 12211 |
| PSMA2 | 12203 |
| ITGAL | 12056 |
| ALAD | 12045 |
| SNAP23 | 11956 |
| IQGAP1 | 11931 |
| DNASE1L1 | 11920 |
| LTA4H | 11893 |
| GLA | 11875 |
| PRKCD | 11872 |
| CCT8 | 11813 |
| ANXA2 | 11716 |
| AGA | 11701 |
| C6orf120 | 11690 |
| PSMD3 | 11655 |
| CD47 | 11617 |
| CD58 | 11554 |
| IDH1 | 11528 |
| ATP8A1 | 11425 |
| FTH1 | 11406 |
| PSMD14 | 11371 |
| ALDOC | 11365 |
| TXNDC5 | 11346 |
| HLA-C | 11297 |
| PSMD1 | 11280 |
| HGSNAT | 11261 |
| IQGAP2 | 11231 |
| RHOA | 11182 |
| ILF2 | 11108 |
| PSAP | 11023 |
| CTSB | 10996 |
| CEP290 | 10987 |
| HLA-A | 10971 |
| ACTR1B | 10947 |
| MIF | 10935 |
| PKM | 10849 |
| SLCO4C1 | 10785 |
| CTSH | 10743 |
| MAPK1 | 10705 |
| EEF2 | 10659 |
| NIT2 | 10636 |
| ACTR10 | 10590 |
| CFD | 10570 |
| VNN1 | 10554 |
| HMGB1 | 10552 |
| VAMP8 | 10475 |
| CAB39 | 10457 |
| PSEN1 | 10427 |
| GPI | 10361 |
| ATG7 | 10354 |
| VAPA | 10346 |
| PFKL | 10325 |
| RAB31 | 10305 |
| GSDMD | 10266 |
| OSTF1 | 10254 |
| TBC1D10C | 10190 |
| DSP | 10069 |
| DERA | 10063 |
| HMOX2 | 10061 |
| GM2A | 9989 |
| GLIPR1 | 9959 |
| CD36 | 9953 |
| HSPA8 | 9895 |
| FAF2 | 9859 |
| TSPAN14 | 9825 |
| PGM1 | 9783 |
| LPCAT1 | 9761 |
| OSCAR | 9699 |
| TUBB | 9694 |
| VAT1 | 9540 |
| ORMDL3 | 9537 |
| CAT | 9504 |
| COMMD3 | 9446 |
| CTSC | 9398 |
| PPIA | 9393 |
| PSMD7 | 9371 |
| HSP90AB1 | 9363 |
| IMPDH2 | 9308 |
| PYGL | 9295 |
| PSMB7 | 9253 |
| ITGAV | 9120 |
| AGPAT2 | 9047 |
| PLEKHO2 | 8935 |
| APEH | 8922 |
| GAA | 8919 |
| ANPEP | 8901 |
| TOM1 | 8877 |
| ARG1 | 8835 |
| YPEL5 | 8825 |
| XRCC5 | 8806 |
| EEF1A1 | 8740 |
| DPP7 | 8739 |
| COPB1 | 8664 |
| ACLY | 8659 |
| LCN2 | 8658 |
| CAP1 | 8634 |
| PTAFR | 8514 |
| PLAUR | 8513 |
| NME2 | 8403 |
| ORM1 | 8400 |
| CSNK2B | 8368 |
| VCL | 8357 |
| CKAP4 | 8327 |
| TIMP2 | 8320 |
| METTL7A | 8298 |
| TTR | 8283 |
| RAB3A | 8176 |
| PSMD12 | 8163 |
| HLA-H | 7975 |
| HUWE1 | 7955 |
| CPNE1 | 7836 |
| NBEAL2 | 7749 |
| PDAP1 | 7739 |
| DYNC1H1 | 7639 |
| RAB24 | 7638 |
| FABP5 | 7635 |
| SERPINA1 | 7622 |
| ROCK1 | 7591 |
| TMEM179B | 7543 |
| SIRPA | 7474 |
| COMMD9 | 7455 |
| NFKB1 | 7409 |
| AP2A2 | 7391 |
| ACAA1 | 7384 |
| HVCN1 | 7380 |
| DYNLT1 | 7253 |
| LYZ | 7247 |
| GOLGA7 | 7208 |
| CST3 | 7101 |
| STBD1 | 7077 |
| HSPA6 | 7061 |
| RAB14 | 6952 |
| PTGES2 | 6882 |
| RAP1B | 6830 |
| CD59 | 6818 |
| MANBA | 6817 |
| SLC11A1 | 6739 |
| HEBP2 | 6631 |
| PA2G4 | 6585 |
| RAB5C | 6565 |
| APRT | 6499 |
| DBNL | 6490 |
| TMEM63A | 6449 |
| CPNE3 | 6354 |
| LAIR1 | 6304 |
| SLC2A5 | 6243 |
| PLAU | 6169 |
| TMEM30A | 6157 |
| RAB4B | 6116 |
| TRAPPC1 | 5956 |
| STK11IP | 5898 |
| GRN | 5836 |
| RAB27A | 5804 |
| RHOG | 5747 |
| PSMA5 | 5657 |
| AP1M1 | 5637 |
| RAB5B | 5611 |
| ARSA | 5552 |
| ADAM10 | 5549 |
| BST2 | 5531 |
| S100P | 5511 |
| LAMTOR3 | 5467 |
| CTSD | 5416 |
| RHOF | 5403 |
| PSMD13 | 5353 |
| HLA-B | 5329 |
| B2M | 5242 |
| DYNC1LI1 | 5237 |
| FUCA1 | 5210 |
| CPPED1 | 5138 |
| SERPINB6 | 5125 |
| ATP11B | 5015 |
| QPCT | 5009 |
| CANT1 | 4969 |
| PSMC2 | 4948 |
| PLAC8 | 4886 |
| DYNLL1 | 4853 |
| PRCP | 4730 |
| SLC15A4 | 4647 |
| ARMC8 | 4638 |
| SPTAN1 | 4610 |
| ARHGAP9 | 4486 |
| JUP | 4478 |
| MGST1 | 4472 |
| NRAS | 4465 |
| MAPK14 | 4391 |
| CYBA | 4283 |
| CRISPLD2 | 4273 |
| SERPINB1 | 4239 |
| SVIP | 4238 |
| AGL | 4233 |
| GDI2 | 4162 |
| IST1 | 4111 |
| PTPRN2 | 3851 |
| UNC13D | 3835 |
| CYFIP1 | 3785 |
| ITGAX | 3756 |
| SDCBP | 3724 |
| IMPDH1 | 3690 |
| HSPA1A | 3603 |
| SCAMP1 | 3566 |
| CAND1 | 3381 |
| RAB10 | 3205 |
| RAB3D | 3155 |
| SLC2A3 | 3116 |
| STOM | 3093 |
| ARPC5 | 3073 |
| PSMC3 | 3070 |
| GLB1 | 3064 |
| CTSS | 2960 |
| GSN | 2952 |
| ATP11A | 2935 |
| CXCR2 | 2899 |
| ACTR2 | 2855 |
| ADGRG3 | 2825 |
| MOSPD2 | 2673 |
| PPIE | 2651 |
| RAB6A | 2578 |
| APAF1 | 2532 |
| QSOX1 | 2518 |
| ATP6AP2 | 2508 |
| ORM2 | 2502 |
| GUSB | 2493 |
| ADAM8 | 2424 |
| GYG1 | 2373 |
| RAP2C | 2257 |
| SIRPB1 | 2169 |
| PECAM1 | 2152 |
| HSP90AA1 | 2096 |
| PSMB1 | 2062 |
| NCKAP1L | 1980 |
| NAPRT | 1945 |
| COTL1 | 1794 |
| AMPD3 | 1688 |
| GHDC | 1682 |
| SLC27A2 | 1635 |
| LAMTOR1 | 1557 |
| CSTB | 1547 |
| SNAP29 | 1422 |
| RNASET2 | 1419 |
| BST1 | 1408 |
| DNAJC13 | 1370 |
| KCNAB2 | 1323 |
| MAN2B1 | 1230 |
| FRK | 1179 |
| CYB5R3 | 1177 |
| NCSTN | 1137 |
| PAFAH1B2 | 953 |
| PSMD11 | 879 |
| RAB18 | 760 |
| FCER1G | 746 |
| ADGRE5 | 651 |
| STK10 | 642 |
| RAP1A | 604 |
| B4GALT1 | 540 |
| CMTM6 | 535 |
| PGM2 | 513 |
| PGRMC1 | 498 |
| GMFG | 450 |
| TCIRG1 | 348 |
| LAMTOR2 | 299 |
| DGAT1 | 222 |
| CRACR2A | 155 |
| PRDX6 | 106 |
| RAC1 | 95 |
| CREG1 | 87 |
| XRCC6 | 67 |
| AHSG | 62 |
Response to elevated platelet cytosolic Ca2+
| 1009 | |
|---|---|
| set | Response to elevated platelet cytosolic Ca2+ |
| setSize | 106 |
| pANOVA | 3.66e-05 |
| s.dist | 0.232 |
| p.adjustANOVA | 0.0021 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MANF | 14533 |
| SERPING1 | 14532 |
| HSPA5 | 14531 |
| KNG1 | 14503 |
| PLG | 14495 |
| IGF2 | 14477 |
| FGA | 14346 |
| SERPINA3 | 14304 |
| LAMP2 | 14291 |
| TGFB1 | 14241 |
| PCYOX1L | 14197 |
| FLNA | 14081 |
| FGB | 14018 |
| ITIH3 | 13927 |
| ACTN1 | 13824 |
| LHFPL2 | 13786 |
| VEGFB | 13646 |
| A1BG | 13591 |
| BRPF3 | 13542 |
| APP | 13532 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MANF | 14533 |
| SERPING1 | 14532 |
| HSPA5 | 14531 |
| KNG1 | 14503 |
| PLG | 14495 |
| IGF2 | 14477 |
| FGA | 14346 |
| SERPINA3 | 14304 |
| LAMP2 | 14291 |
| TGFB1 | 14241 |
| PCYOX1L | 14197 |
| FLNA | 14081 |
| FGB | 14018 |
| ITIH3 | 13927 |
| ACTN1 | 13824 |
| LHFPL2 | 13786 |
| VEGFB | 13646 |
| A1BG | 13591 |
| BRPF3 | 13542 |
| APP | 13532 |
| ANXA5 | 13476 |
| ALDOA | 13474 |
| APOA1 | 13433 |
| SERPINF2 | 13388 |
| TOR4A | 13305 |
| PDGFB | 13263 |
| TIMP1 | 13158 |
| PFN1 | 13146 |
| SERPINA4 | 12966 |
| HABP4 | 12946 |
| TAGLN2 | 12885 |
| TLN1 | 12872 |
| FGG | 12809 |
| CD63 | 12800 |
| ABCC4 | 12699 |
| FAM3C | 12377 |
| NHLRC2 | 12356 |
| ITIH4 | 12212 |
| WDR1 | 12167 |
| CFL1 | 12075 |
| CYB5R1 | 11951 |
| PROS1 | 11519 |
| THBS1 | 11408 |
| SERPINE1 | 11217 |
| TF | 11111 |
| PSAP | 11023 |
| SOD1 | 10975 |
| APOH | 10937 |
| LEFTY2 | 10803 |
| CLU | 10723 |
| CD109 | 10579 |
| CFD | 10570 |
| TMX3 | 10142 |
| TMSB4X | 10078 |
| CD36 | 9953 |
| ACTN4 | 9828 |
| CALU | 9602 |
| VEGFA | 9433 |
| HRG | 9408 |
| PPIA | 9393 |
| APOOL | 9286 |
| CAP1 | 8634 |
| ORM1 | 8400 |
| VCL | 8357 |
| ENDOD1 | 8089 |
| TEX264 | 7996 |
| GTPBP2 | 7790 |
| CD9 | 7746 |
| SERPINA1 | 7622 |
| FERMT3 | 7573 |
| STXBP3 | 7400 |
| APLP2 | 7009 |
| LGALS3BP | 6917 |
| FN1 | 6525 |
| TIMP3 | 6229 |
| ALB | 5965 |
| ECM1 | 5858 |
| CHID1 | 5583 |
| PDGFA | 5524 |
| GAS6 | 5226 |
| PRKCA | 4709 |
| SCCPDH | 4529 |
| VWF | 3777 |
| SPARC | 3167 |
| SPP2 | 3138 |
| CDC37L1 | 3066 |
| SELENOP | 2773 |
| QSOX1 | 2518 |
| ORM2 | 2502 |
| SYTL4 | 2386 |
| A2M | 2340 |
| PECAM1 | 2152 |
| RARRES2 | 1845 |
| F5 | 1638 |
| VTI1B | 1619 |
| OLA1 | 1578 |
| STXBP2 | 1474 |
| F8 | 1460 |
| ITGA2B | 1391 |
| CALM1 | 1340 |
| TUBA4A | 1335 |
| STX4 | 995 |
| MAGED2 | 745 |
| TGFB3 | 649 |
| PHACTR2 | 144 |
| AHSG | 62 |
Transferrin endocytosis and recycling
| 1282 | |
|---|---|
| set | Transferrin endocytosis and recycling |
| setSize | 29 |
| pANOVA | 5.72e-05 |
| s.dist | 0.432 |
| p.adjustANOVA | 0.00308 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| ATP6V0B | 14422 |
| STEAP3 | 14327 |
| ATP6V0A1 | 14310 |
| ATP6V1D | 14228 |
| ATP6V0D1 | 14206 |
| ATP6V0A2 | 14162 |
| TFRC | 13755 |
| ATP6V0E1 | 13731 |
| MCOLN1 | 13693 |
| TFR2 | 13670 |
| ATP6V1E1 | 13114 |
| ATP6AP1 | 13046 |
| ATP6V0C | 12764 |
| ATP6V1C2 | 12453 |
| HFE | 11997 |
| ATP6V1B2 | 11744 |
| ATP6V1G1 | 11283 |
| TF | 11111 |
| ATP6V0E2 | 10798 |
| ATP6V1C1 | 10444 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ATP6V0B | 14422 |
| STEAP3 | 14327 |
| ATP6V0A1 | 14310 |
| ATP6V1D | 14228 |
| ATP6V0D1 | 14206 |
| ATP6V0A2 | 14162 |
| TFRC | 13755 |
| ATP6V0E1 | 13731 |
| MCOLN1 | 13693 |
| TFR2 | 13670 |
| ATP6V1E1 | 13114 |
| ATP6AP1 | 13046 |
| ATP6V0C | 12764 |
| ATP6V1C2 | 12453 |
| HFE | 11997 |
| ATP6V1B2 | 11744 |
| ATP6V1G1 | 11283 |
| TF | 11111 |
| ATP6V0E2 | 10798 |
| ATP6V1C1 | 10444 |
| STEAP2 | 10271 |
| ATP6V1H | 9358 |
| ATP6V1B1 | 8635 |
| ATP6V1A | 7965 |
| ATP6V1F | 1771 |
| ATP6V0D2 | 1494 |
| ATP6V1G2 | 1360 |
| ATP6V1E2 | 1090 |
| TCIRG1 | 348 |
DNA strand elongation
| 230 | |
|---|---|
| set | DNA strand elongation |
| setSize | 32 |
| pANOVA | 5.82e-05 |
| s.dist | 0.411 |
| p.adjustANOVA | 0.00308 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| GINS1 | 14342 |
| MCM5 | 13415 |
| PRIM1 | 13355 |
| RPA2 | 13354 |
| GINS2 | 13245 |
| MCM6 | 12996 |
| GINS3 | 12937 |
| MCM2 | 12926 |
| POLA2 | 12805 |
| MCM4 | 12667 |
| PRIM2 | 12596 |
| GINS4 | 12516 |
| PCNA | 12452 |
| RPA3 | 12149 |
| LIG1 | 11811 |
| POLD1 | 11069 |
| RPA1 | 10563 |
| RFC1 | 10506 |
| RFC3 | 10111 |
| POLA1 | 9387 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| GINS1 | 14342 |
| MCM5 | 13415 |
| PRIM1 | 13355 |
| RPA2 | 13354 |
| GINS2 | 13245 |
| MCM6 | 12996 |
| GINS3 | 12937 |
| MCM2 | 12926 |
| POLA2 | 12805 |
| MCM4 | 12667 |
| PRIM2 | 12596 |
| GINS4 | 12516 |
| PCNA | 12452 |
| RPA3 | 12149 |
| LIG1 | 11811 |
| POLD1 | 11069 |
| RPA1 | 10563 |
| RFC1 | 10506 |
| RFC3 | 10111 |
| POLA1 | 9387 |
| POLD2 | 9350 |
| MCM3 | 9054 |
| RFC4 | 8885 |
| MCM8 | 8710 |
| POLD3 | 8459 |
| RFC5 | 8324 |
| RFC2 | 7371 |
| POLD4 | 6907 |
| DNA2 | 6486 |
| MCM7 | 4863 |
| CDC45 | 3490 |
| FEN1 | 721 |
Cellular responses to stimuli
| 155 | |
|---|---|
| set | Cellular responses to stimuli |
| setSize | 641 |
| pANOVA | 7.93e-05 |
| s.dist | 0.092 |
| p.adjustANOVA | 0.00404 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| HSPA5 | 14531 |
| CALR | 14529 |
| DNAJB11 | 14528 |
| HYOU1 | 14527 |
| HERPUD1 | 14524 |
| DNAJC3 | 14516 |
| HSP90B1 | 14514 |
| DNAJB9 | 14510 |
| TXNIP | 14509 |
| SYVN1 | 14485 |
| PDIA6 | 14482 |
| EDEM1 | 14479 |
| WFS1 | 14466 |
| ATP6V0B | 14422 |
| CSRP1 | 14410 |
| GFPT1 | 14406 |
| DDIT3 | 14401 |
| EIF2AK3 | 14371 |
| HM13 | 14368 |
| SOD2 | 14367 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HSPA5 | 14531 |
| CALR | 14529 |
| DNAJB11 | 14528 |
| HYOU1 | 14527 |
| HERPUD1 | 14524 |
| DNAJC3 | 14516 |
| HSP90B1 | 14514 |
| DNAJB9 | 14510 |
| TXNIP | 14509 |
| SYVN1 | 14485 |
| PDIA6 | 14482 |
| EDEM1 | 14479 |
| WFS1 | 14466 |
| ATP6V0B | 14422 |
| CSRP1 | 14410 |
| GFPT1 | 14406 |
| DDIT3 | 14401 |
| EIF2AK3 | 14371 |
| HM13 | 14368 |
| SOD2 | 14367 |
| FLCN | 14362 |
| RRAGC | 14345 |
| MAFK | 14318 |
| RPL36AL | 14313 |
| MYDGF | 14306 |
| SERP1 | 14288 |
| MT-CO3 | 14274 |
| ATF6 | 14261 |
| KDM6B | 14253 |
| WIPI1 | 14251 |
| ATP6V1D | 14228 |
| RPS19BP1 | 14217 |
| SHC1 | 14209 |
| ATP6V0D1 | 14206 |
| SSR1 | 14205 |
| FKBP14 | 14184 |
| SRPRB | 14181 |
| P4HB | 14170 |
| ERN1 | 14152 |
| CREB3L2 | 14080 |
| ATF5 | 14076 |
| SEC13 | 14049 |
| TXNRD1 | 14041 |
| TRIB3 | 14029 |
| HSPA13 | 14005 |
| TSPYL2 | 14002 |
| PPP1R15A | 13999 |
| FNIP1 | 13998 |
| EGLN2 | 13975 |
| MT1G | 13955 |
| NCOA6 | 13941 |
| RRAGD | 13938 |
| PPARA | 13906 |
| VCP | 13902 |
| HDGF | 13896 |
| MT1F | 13868 |
| PRDX1 | 13828 |
| PSMF1 | 13810 |
| UBE2C | 13793 |
| CRTC2 | 13780 |
| SCO2 | 13759 |
| ATP6V0E1 | 13731 |
| SESN2 | 13712 |
| LMNB1 | 13707 |
| NUP37 | 13706 |
| E2F1 | 13694 |
| HSPA9 | 13667 |
| COX20 | 13633 |
| HSPH1 | 13584 |
| EXOSC6 | 13547 |
| VHL | 13531 |
| DNAJC7 | 13527 |
| KEAP1 | 13510 |
| EP300 | 13485 |
| TATDN2 | 13480 |
| MAPKAPK2 | 13468 |
| PSME4 | 13450 |
| APOA1 | 13433 |
| PSMD2 | 13423 |
| GPX2 | 13379 |
| TPP1 | 13378 |
| RPA2 | 13354 |
| CBX2 | 13350 |
| EXTL1 | 13312 |
| POM121 | 13281 |
| DNAJB1 | 13228 |
| CHAC1 | 13119 |
| ATP6V1E1 | 13114 |
| NUP210 | 13025 |
| ATF2 | 12933 |
| TLN1 | 12872 |
| ATP6V0C | 12764 |
| HIRA | 12746 |
| SCMH1 | 12722 |
| POM121C | 12687 |
| MAPK3 | 12684 |
| CXXC1 | 12670 |
| ERF | 12637 |
| MEF2D | 12594 |
| CCNA2 | 12587 |
| AKT1S1 | 12584 |
| CEBPG | 12578 |
| AGO4 | 12561 |
| ADD1 | 12538 |
| MBTPS1 | 12523 |
| PSMD6 | 12502 |
| ABCC1 | 12501 |
| ATP6V1C2 | 12453 |
| MT-CO1 | 12380 |
| SIN3A | 12373 |
| RORA | 12360 |
| PPARGC1A | 12350 |
| UBN1 | 12306 |
| E2F2 | 12251 |
| MOV10 | 12217 |
| FKBP4 | 12213 |
| AGO3 | 12205 |
| PSMA2 | 12203 |
| MAP4K4 | 12181 |
| RPA3 | 12149 |
| MAPKAPK3 | 12147 |
| SEC31A | 12138 |
| LRPPRC | 12122 |
| PSMA1 | 12052 |
| ANAPC16 | 12018 |
| ATF4 | 11932 |
| DDX11 | 11907 |
| ANAPC7 | 11895 |
| PRKCD | 11872 |
| EZH2 | 11860 |
| SIRT1 | 11855 |
| ASNS | 11814 |
| ATP6V1B2 | 11744 |
| PSMC1 | 11724 |
| HIKESHI | 11695 |
| POT1 | 11678 |
| SLC38A9 | 11664 |
| PSMD3 | 11655 |
| CDC23 | 11639 |
| HSPB8 | 11600 |
| GRB10 | 11598 |
| FNIP2 | 11587 |
| CA9 | 11579 |
| NUP107 | 11561 |
| PSME2 | 11555 |
| ANAPC10 | 11551 |
| DYNLL2 | 11507 |
| MED1 | 11468 |
| AJUBA | 11454 |
| AQP8 | 11449 |
| NCF2 | 11446 |
| CREB3L3 | 11433 |
| SP1 | 11396 |
| NPAS2 | 11394 |
| NUP35 | 11387 |
| PSMD14 | 11371 |
| HSPA14 | 11362 |
| HDAC6 | 11333 |
| SKP2 | 11323 |
| XBP1 | 11302 |
| ATP6V1G1 | 11283 |
| PSMD1 | 11280 |
| CREB3L4 | 11259 |
| BAG3 | 11246 |
| LAMTOR5 | 11181 |
| TERF1 | 11145 |
| NUP205 | 11144 |
| RPL19 | 11094 |
| BAG5 | 11071 |
| NUP93 | 11067 |
| HMGA1 | 11043 |
| SOD1 | 10975 |
| EIF2S1 | 10961 |
| FOS | 10931 |
| ACTR1A | 10903 |
| DNAJB6 | 10856 |
| RPS7 | 10850 |
| PPP2R5B | 10834 |
| DCP2 | 10825 |
| ATP6V0E2 | 10798 |
| GSK3B | 10767 |
| HMGA2 | 10714 |
| UBA52 | 10707 |
| MAPK1 | 10705 |
| CDK4 | 10698 |
| CSNK2A1 | 10637 |
| COL4A6 | 10629 |
| COX5A | 10625 |
| RPL11 | 10624 |
| RPL10 | 10608 |
| ACTR10 | 10590 |
| RPS15 | 10567 |
| RPA1 | 10563 |
| NUP188 | 10521 |
| FAU | 10520 |
| DEPDC5 | 10518 |
| TACO1 | 10511 |
| RPL14 | 10500 |
| BACH1 | 10478 |
| CRTC3 | 10469 |
| ATP6V1C1 | 10444 |
| ANAPC15 | 10442 |
| PSMB9 | 10430 |
| MT1E | 10415 |
| HSPA12A | 10402 |
| ATR | 10396 |
| EPAS1 | 10387 |
| PSMB6 | 10326 |
| PSMC6 | 10307 |
| CDKN2D | 10296 |
| CAPZA1 | 10272 |
| GPX3 | 10217 |
| RRAGB | 10211 |
| PSMC4 | 10196 |
| TNRC6C | 10180 |
| SRPRA | 10175 |
| DNAJC2 | 10157 |
| RPS5 | 10135 |
| NUP88 | 10134 |
| H2AFX | 10131 |
| EXOSC5 | 10117 |
| FKBP5 | 10097 |
| HMOX2 | 10061 |
| NUP50 | 10047 |
| RPS11 | 9977 |
| NCOA1 | 9914 |
| RPS19 | 9909 |
| HSPA8 | 9895 |
| RPS28 | 9891 |
| PSMD9 | 9853 |
| CHD9 | 9842 |
| GCN1 | 9826 |
| EXOSC7 | 9819 |
| NR1D1 | 9818 |
| CREBRF | 9731 |
| PARN | 9715 |
| RBBP7 | 9712 |
| PSMD5 | 9676 |
| CSNK2A2 | 9641 |
| FABP1 | 9636 |
| NFYB | 9634 |
| BAG1 | 9631 |
| COX8A | 9591 |
| MAP2K4 | 9558 |
| SZT2 | 9557 |
| CAT | 9504 |
| SEH1L | 9474 |
| CTDSP2 | 9444 |
| EIF2S2 | 9437 |
| VEGFA | 9433 |
| SESN1 | 9414 |
| PSMD7 | 9371 |
| HSP90AB1 | 9363 |
| ATP6V1H | 9358 |
| PSMD10 | 9356 |
| NCOR2 | 9331 |
| WDR59 | 9316 |
| MAP2K7 | 9311 |
| RPLP1 | 9291 |
| MAPK7 | 9270 |
| NCOR1 | 9256 |
| PSMB7 | 9253 |
| NPRL2 | 9247 |
| TNIK | 9243 |
| CBX8 | 9242 |
| RPS12 | 9239 |
| COX7A2L | 9228 |
| CCS | 9214 |
| TFDP2 | 9210 |
| FBXL17 | 9200 |
| ST13 | 9142 |
| NUP155 | 9102 |
| EGLN1 | 9096 |
| HELZ2 | 9086 |
| RPL27A | 9081 |
| NCOA2 | 9072 |
| RPLP0 | 9067 |
| TERF2IP | 9056 |
| PHC1 | 9053 |
| CDK6 | 9023 |
| UBB | 9013 |
| PLA2G4B | 8953 |
| MT1X | 8940 |
| TNRC6B | 8904 |
| PSMA4 | 8902 |
| STAP2 | 8852 |
| BMI1 | 8838 |
| HIF1A | 8807 |
| RPL35A | 8797 |
| EEF1A1 | 8740 |
| CUL1 | 8725 |
| HMOX1 | 8715 |
| PSMD4 | 8670 |
| CAMK2A | 8669 |
| PSMC5 | 8646 |
| ATP6V1B1 | 8635 |
| RPL30 | 8630 |
| RAD50 | 8623 |
| RXRA | 8607 |
| NBN | 8606 |
| CBX4 | 8580 |
| MAPKAPK5 | 8556 |
| COX4I1 | 8531 |
| RPS9 | 8515 |
| ID1 | 8511 |
| TERF2 | 8496 |
| KPTN | 8495 |
| NR3C1 | 8476 |
| COX14 | 8475 |
| WDR24 | 8468 |
| UBE2D3 | 8449 |
| HIF3A | 8437 |
| IMPACT | 8414 |
| RPL18 | 8381 |
| DCTN2 | 8375 |
| CSNK2B | 8368 |
| MTF1 | 8354 |
| SERPINH1 | 8349 |
| RAE1 | 8335 |
| CUL7 | 8310 |
| IGFBP1 | 8301 |
| TINF2 | 8275 |
| DYNC1LI2 | 8235 |
| CREBBP | 8214 |
| RPL26L1 | 8188 |
| COX7B | 8175 |
| AGO1 | 8173 |
| PSMD12 | 8163 |
| HIF1AN | 8161 |
| RPS6KA1 | 8159 |
| RPS29 | 8133 |
| RPL6 | 8132 |
| IGFBP7 | 8108 |
| STAT3 | 8078 |
| PSME3 | 8052 |
| KLHDC3 | 8036 |
| CDKN2C | 8034 |
| CITED2 | 8029 |
| ATP6V1A | 7965 |
| NUP85 | 7946 |
| NUP98 | 7940 |
| RHEB | 7936 |
| WTIP | 7931 |
| EP400 | 7921 |
| NPRL3 | 7917 |
| ACADVL | 7903 |
| LMNA | 7854 |
| RBX1 | 7850 |
| COX19 | 7838 |
| CDK2 | 7809 |
| GSK3A | 7787 |
| MTOR | 7785 |
| MRE11 | 7780 |
| DEDD2 | 7779 |
| EIF2S3 | 7757 |
| CREB3 | 7725 |
| RING1 | 7710 |
| DCTN5 | 7690 |
| SIN3B | 7646 |
| DYNC1H1 | 7639 |
| BAG4 | 7633 |
| TXN | 7626 |
| CDKN1A | 7569 |
| STIP1 | 7550 |
| RPL28 | 7500 |
| ANAPC5 | 7485 |
| HSPA4L | 7475 |
| GSR | 7463 |
| RPSA | 7435 |
| ASF1A | 7415 |
| NFKB1 | 7409 |
| RPL8 | 7307 |
| RPS4X | 7297 |
| RPS2 | 7293 |
| EXOSC3 | 7270 |
| RPL29 | 7265 |
| RPL32 | 7263 |
| RPL36 | 7221 |
| COX18 | 7215 |
| RPL37 | 7194 |
| EXOSC2 | 7192 |
| RPS17 | 7104 |
| PTGES3 | 7103 |
| UBE2E1 | 7102 |
| PHC2 | 7072 |
| HSPA6 | 7061 |
| RPS24 | 7060 |
| CDKN2A | 7056 |
| MAP2K3 | 7038 |
| MBTPS2 | 7019 |
| SH3BP4 | 7014 |
| ATOX1 | 6974 |
| RBBP4 | 6938 |
| CXCL8 | 6916 |
| CCAR2 | 6864 |
| RPS14 | 6851 |
| DNAJA2 | 6843 |
| EXTL3 | 6822 |
| ETS1 | 6791 |
| UBE2D1 | 6734 |
| CARM1 | 6725 |
| ZBTB17 | 6703 |
| EXOSC1 | 6667 |
| RPS27L | 6664 |
| COX6B1 | 6617 |
| RPS10 | 6612 |
| SEM1 | 6566 |
| HSPA2 | 6538 |
| COX6A1 | 6487 |
| EXTL2 | 6440 |
| PSMA3 | 6422 |
| NUP54 | 6371 |
| CUL3 | 6363 |
| PTK6 | 6358 |
| EXOSC9 | 6333 |
| RPS6KA3 | 6316 |
| HBA1 | 6302 |
| RPS15A | 6295 |
| SCO1 | 6294 |
| ELOB | 6272 |
| RPL7 | 6223 |
| RPL34 | 6203 |
| EXOSC4 | 6193 |
| APOB | 6172 |
| JUN | 6103 |
| PSMD8 | 6091 |
| GPX1 | 6089 |
| RPS21 | 6082 |
| EIF2AK1 | 6069 |
| RPS16 | 6026 |
| RPS3 | 5985 |
| RPL13A | 5970 |
| ALB | 5965 |
| RPLP2 | 5950 |
| RPL35 | 5927 |
| ACD | 5857 |
| DYNC1I2 | 5783 |
| RPS27A | 5776 |
| LIMD1 | 5738 |
| CRTC1 | 5705 |
| AAAS | 5701 |
| MAPK10 | 5681 |
| PSMA5 | 5657 |
| MIOS | 5610 |
| CBX6 | 5608 |
| RPL23A | 5592 |
| RPL10A | 5584 |
| RPS6 | 5569 |
| RPL36A | 5542 |
| RPS18 | 5504 |
| RPL41 | 5472 |
| RELA | 5468 |
| LAMTOR3 | 5467 |
| NUP43 | 5410 |
| RPS13 | 5366 |
| TFDP1 | 5361 |
| PSMD13 | 5353 |
| RPL4 | 5324 |
| MDM4 | 5318 |
| CCNE1 | 5315 |
| GPX7 | 5287 |
| DYNC1LI1 | 5237 |
| NUP153 | 5230 |
| NFYA | 5142 |
| RPS23 | 5114 |
| RPL37A | 5072 |
| RRAGA | 5038 |
| HSF1 | 5003 |
| EGLN3 | 5001 |
| PSMC2 | 4948 |
| MAP2K6 | 4868 |
| PSME1 | 4861 |
| DYNLL1 | 4853 |
| ATF3 | 4803 |
| DNAJA1 | 4793 |
| RNF2 | 4732 |
| RPL39 | 4713 |
| RPL18A | 4649 |
| RPL7A | 4625 |
| NUP58 | 4603 |
| EED | 4581 |
| ETS2 | 4533 |
| TNFRSF21 | 4491 |
| CABIN1 | 4476 |
| SMARCD3 | 4455 |
| MAPK14 | 4391 |
| RPS4Y1 | 4388 |
| MINK1 | 4372 |
| NFE2L2 | 4363 |
| CYBA | 4283 |
| RPL27 | 4268 |
| TGS1 | 4181 |
| CAMK2G | 4176 |
| ITFG2 | 4172 |
| RPL22 | 4170 |
| CCNE2 | 4152 |
| TP53 | 4144 |
| ATP7A | 4123 |
| RAI1 | 4118 |
| EPO | 4044 |
| DCTN4 | 3979 |
| NUP214 | 3957 |
| PSMB3 | 3928 |
| RPL23 | 3923 |
| ANAPC1 | 3900 |
| UBE2S | 3839 |
| XPO1 | 3824 |
| RPL24 | 3686 |
| PSMB2 | 3678 |
| MLST8 | 3677 |
| RPL38 | 3652 |
| HSPA1A | 3603 |
| LAMTOR4 | 3602 |
| TNRC6A | 3580 |
| RPS20 | 3578 |
| RPL26 | 3560 |
| MAPK9 | 3449 |
| EHMT1 | 3422 |
| CLOCK | 3360 |
| CAMK2D | 3358 |
| CDKN2B | 3352 |
| ANAPC2 | 3349 |
| DCTN1 | 3338 |
| TBL1X | 3308 |
| ARFGAP1 | 3224 |
| DIS3 | 3190 |
| CAPZA2 | 3143 |
| ANAPC11 | 3134 |
| KAT5 | 3115 |
| CDC27 | 3103 |
| PSMC3 | 3070 |
| NDC1 | 3023 |
| COX11 | 3007 |
| NR3C2 | 2999 |
| ATM | 2965 |
| EIF2AK4 | 2950 |
| COX7C | 2931 |
| BLVRA | 2921 |
| DCTN3 | 2887 |
| PREB | 2868 |
| TBL1XR1 | 2795 |
| RPL21 | 2755 |
| HSBP1 | 2726 |
| NUP133 | 2708 |
| LY96 | 2689 |
| RPL15 | 2637 |
| PRDX5 | 2560 |
| BAG2 | 2521 |
| GOSR2 | 2441 |
| CAPZB | 2376 |
| RPL3 | 2369 |
| RPS6KA2 | 2339 |
| PSMB4 | 2330 |
| CDC16 | 2309 |
| CEBPB | 2300 |
| MT2A | 2284 |
| RPL17 | 2280 |
| RPS8 | 2190 |
| HSP90AA1 | 2096 |
| PSMB1 | 2062 |
| SULT1A3 | 2038 |
| KHSRP | 2029 |
| RPL12 | 2000 |
| ARNT | 1996 |
| PRDX2 | 1951 |
| MDM2 | 1942 |
| KDELR3 | 1922 |
| RPS25 | 1901 |
| UBE2D2 | 1857 |
| COX16 | 1851 |
| CRYAB | 1848 |
| PSMA7 | 1820 |
| HSPA4 | 1816 |
| MRPL18 | 1806 |
| ATP6V1F | 1771 |
| SLC46A1 | 1702 |
| PHC3 | 1660 |
| BLVRB | 1602 |
| CDKN1B | 1590 |
| LAMTOR1 | 1557 |
| UBC | 1551 |
| ATP6V0D2 | 1494 |
| GPX8 | 1486 |
| PSMB5 | 1484 |
| HIGD1A | 1427 |
| RPL13 | 1426 |
| MAPK8 | 1418 |
| MT-CO2 | 1414 |
| NFYC | 1395 |
| COX5B | 1393 |
| ATP6V1G2 | 1360 |
| ELOC | 1265 |
| BMT2 | 1250 |
| PDIA5 | 1130 |
| SKP1 | 1117 |
| NRIP1 | 1114 |
| TPR | 1105 |
| CYCS | 1098 |
| ATP6V1E2 | 1090 |
| RPL5 | 1001 |
| CREB1 | 935 |
| EXOSC8 | 928 |
| RB1 | 925 |
| PSMD11 | 879 |
| E2F3 | 876 |
| PSMB10 | 838 |
| RPS26 | 827 |
| RPTOR | 803 |
| NDUFA4 | 795 |
| EHMT2 | 784 |
| ARNTL | 732 |
| CUL2 | 703 |
| NUP160 | 683 |
| DCTN6 | 666 |
| SUZ12 | 664 |
| COX6C | 661 |
| MT1A | 643 |
| RPL31 | 638 |
| SURF1 | 631 |
| NUP62 | 618 |
| TXNRD2 | 603 |
| ANAPC4 | 595 |
| NUDT2 | 589 |
| RPL9 | 509 |
| TXN2 | 499 |
| MAPK11 | 492 |
| RPL22L1 | 439 |
| ERO1A | 403 |
| CDC26 | 402 |
| FZR1 | 397 |
| YIF1A | 381 |
| RPS3A | 369 |
| TCIRG1 | 348 |
| PRDX3 | 321 |
| RPS27 | 312 |
| LAMTOR2 | 299 |
| PSMA6 | 261 |
| YWHAE | 253 |
| PRDX6 | 106 |
| HDAC3 | 84 |
| RANBP2 | 9 |
Collagen degradation
| 183 | |
|---|---|
| set | Collagen degradation |
| setSize | 20 |
| pANOVA | 9.85e-05 |
| s.dist | 0.503 |
| p.adjustANOVA | 0.00482 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| COL16A1 | 14435 |
| COL9A2 | 14389 |
| MMP11 | 14360 |
| TMPRSS6 | 14341 |
| CTSL | 14263 |
| COL18A1 | 14139 |
| FURIN | 13851 |
| COL9A3 | 13817 |
| PHYKPL | 12912 |
| ADAM17 | 12276 |
| MMP14 | 11612 |
| CTSB | 10996 |
| CTSK | 10213 |
| ADAM9 | 10018 |
| MMP2 | 9932 |
| MMP15 | 6696 |
| COL26A1 | 5699 |
| ADAM10 | 5549 |
| CTSD | 5416 |
| MMP3 | 3425 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| COL16A1 | 14435 |
| COL9A2 | 14389 |
| MMP11 | 14360 |
| TMPRSS6 | 14341 |
| CTSL | 14263 |
| COL18A1 | 14139 |
| FURIN | 13851 |
| COL9A3 | 13817 |
| PHYKPL | 12912 |
| ADAM17 | 12276 |
| MMP14 | 11612 |
| CTSB | 10996 |
| CTSK | 10213 |
| ADAM9 | 10018 |
| MMP2 | 9932 |
| MMP15 | 6696 |
| COL26A1 | 5699 |
| ADAM10 | 5549 |
| CTSD | 5416 |
| MMP3 | 3425 |
Signaling by Rho GTPases, Miro GTPases and RHOBTB3
| 1149 | |
|---|---|
| set | Signaling by Rho GTPases, Miro GTPases and RHOBTB3 |
| setSize | 566 |
| pANOVA | 0.000102 |
| s.dist | 0.0962 |
| p.adjustANOVA | 0.00482 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| STEAP3 | 14327 |
| ARHGEF2 | 14307 |
| RHOQ | 14296 |
| DVL3 | 14293 |
| JAG1 | 14259 |
| ARHGEF28 | 14232 |
| CDH1 | 14202 |
| ARHGAP32 | 14201 |
| PLD1 | 14191 |
| RHOBTB2 | 14141 |
| EPHA2 | 14124 |
| ACTG1 | 14090 |
| GOLGA3 | 14085 |
| FLNA | 14081 |
| SEC13 | 14049 |
| RHOC | 13943 |
| VCP | 13902 |
| NDC80 | 13840 |
| ACTN1 | 13824 |
| FLOT2 | 13811 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| STEAP3 | 14327 |
| ARHGEF2 | 14307 |
| RHOQ | 14296 |
| DVL3 | 14293 |
| JAG1 | 14259 |
| ARHGEF28 | 14232 |
| CDH1 | 14202 |
| ARHGAP32 | 14201 |
| PLD1 | 14191 |
| RHOBTB2 | 14141 |
| EPHA2 | 14124 |
| ACTG1 | 14090 |
| GOLGA3 | 14085 |
| FLNA | 14081 |
| SEC13 | 14049 |
| RHOC | 13943 |
| VCP | 13902 |
| NDC80 | 13840 |
| ACTN1 | 13824 |
| FLOT2 | 13811 |
| NUDC | 13808 |
| EMC3 | 13805 |
| MYL12B | 13785 |
| RHOBTB3 | 13761 |
| TFRC | 13755 |
| KIF5A | 13752 |
| LMNB1 | 13707 |
| NUP37 | 13706 |
| AKAP13 | 13699 |
| DLC1 | 13698 |
| GNA13 | 13689 |
| TUBA1B | 13681 |
| RAPGEF1 | 13680 |
| PRKCZ | 13676 |
| NF2 | 13642 |
| KNL1 | 13621 |
| MAD2L1 | 13616 |
| WASL | 13611 |
| NGEF | 13605 |
| ESYT1 | 13601 |
| VRK2 | 13580 |
| SEMA4F | 13579 |
| ANKLE2 | 13567 |
| VHL | 13531 |
| FGD3 | 13525 |
| CENPK | 13518 |
| SPC24 | 13498 |
| ANKRD26 | 13489 |
| NUF2 | 13470 |
| ARHGAP35 | 13445 |
| BUB1B | 13431 |
| TMPO | 13363 |
| MYL6 | 13325 |
| FNBP1 | 13314 |
| TMEM59 | 13311 |
| MIS12 | 13304 |
| IQGAP3 | 13282 |
| CDC42EP4 | 13265 |
| DSN1 | 13258 |
| BAIAP2L1 | 13253 |
| AURKB | 13190 |
| ARHGAP39 | 13184 |
| PFN2 | 13179 |
| PFN1 | 13146 |
| CPD | 13139 |
| OCRL | 13103 |
| CDC25C | 13084 |
| LCK | 13069 |
| RBBP6 | 13058 |
| ATP6AP1 | 13046 |
| PTK2B | 13043 |
| CLTC | 13017 |
| SH3RF1 | 13005 |
| SPEN | 12976 |
| SRGAP3 | 12970 |
| ARHGAP19 | 12886 |
| SHMT2 | 12864 |
| SPDL1 | 12856 |
| BCAP31 | 12840 |
| ARPC4 | 12778 |
| KNTC1 | 12758 |
| KIDINS220 | 12710 |
| CDCA8 | 12700 |
| MAPK3 | 12684 |
| CKAP5 | 12651 |
| STARD13 | 12646 |
| RAB9A | 12633 |
| RHPN1 | 12589 |
| MFN2 | 12586 |
| DDRGK1 | 12585 |
| SLC1A5 | 12542 |
| RASGRF2 | 12510 |
| PRC1 | 12500 |
| CLIP1 | 12494 |
| LETM1 | 12482 |
| CDC42BPA | 12468 |
| SPATA13 | 12459 |
| CCT2 | 12444 |
| MYO9B | 12432 |
| SKA2 | 12421 |
| CCT6A | 12336 |
| ARHGEF40 | 12329 |
| UBXN11 | 12284 |
| HTR7 | 12283 |
| RTKN | 12273 |
| KIF2A | 12231 |
| RAB7A | 12220 |
| DIAPH1 | 12211 |
| ITGB3BP | 12199 |
| LIMK2 | 12193 |
| WHAMM | 12191 |
| FGD4 | 12166 |
| OPHN1 | 12089 |
| PPP2R5A | 12088 |
| CFL1 | 12075 |
| NET1 | 12058 |
| WASF1 | 12021 |
| RCC2 | 12011 |
| TOR1AIP1 | 11985 |
| PLXND1 | 11963 |
| SNAP23 | 11956 |
| SOWAHC | 11934 |
| IQGAP1 | 11931 |
| NDEL1 | 11904 |
| ZWILCH | 11891 |
| DLG5 | 11889 |
| CENPH | 11884 |
| PRKCD | 11872 |
| ARHGAP42 | 11866 |
| HINT2 | 11856 |
| TJP2 | 11851 |
| CYFIP2 | 11850 |
| CCP110 | 11807 |
| GIT1 | 11767 |
| CTNNA1 | 11711 |
| DEPDC1B | 11636 |
| ARHGAP44 | 11618 |
| FAM13B | 11613 |
| SH3PXD2A | 11583 |
| ARHGAP11B | 11580 |
| ANKFY1 | 11567 |
| CDC42EP2 | 11566 |
| NUP107 | 11561 |
| RHOB | 11537 |
| MTR | 11525 |
| DYNLL2 | 11507 |
| CIT | 11482 |
| NCF2 | 11446 |
| BRK1 | 11428 |
| TNFAIP1 | 11426 |
| KIF5B | 11419 |
| TMEM87A | 11413 |
| NISCH | 11403 |
| SOS2 | 11402 |
| ZWINT | 11400 |
| PLIN3 | 11389 |
| KIF2C | 11386 |
| RHOBTB1 | 11372 |
| CENPI | 11351 |
| ARL13B | 11337 |
| ARHGDIA | 11324 |
| PAK4 | 11295 |
| CDC42BPB | 11293 |
| PARD6A | 11269 |
| TRIO | 11264 |
| IQGAP2 | 11231 |
| CENPQ | 11227 |
| CHN2 | 11204 |
| STX5 | 11191 |
| ACTR3 | 11186 |
| RHOA | 11182 |
| FARP1 | 11169 |
| ARHGEF11 | 11110 |
| RNF20 | 11085 |
| GMIP | 11044 |
| SYDE1 | 11040 |
| RBMX | 11027 |
| PIK3C3 | 11026 |
| RACGAP1 | 10990 |
| RAP1GDS1 | 10985 |
| CDC37 | 10941 |
| PPP2CA | 10917 |
| COPS2 | 10902 |
| WWP2 | 10881 |
| KDM4C | 10878 |
| SLK | 10872 |
| PPP2R5B | 10834 |
| SAMM50 | 10805 |
| ADD3 | 10801 |
| DBN1 | 10764 |
| CENPC | 10756 |
| CDC20 | 10732 |
| MAPK1 | 10705 |
| PLEKHG2 | 10691 |
| ACTB | 10683 |
| ZAP70 | 10613 |
| CENPE | 10538 |
| RRAS2 | 10503 |
| PAK2 | 10458 |
| ARHGAP23 | 10454 |
| NOXA1 | 10451 |
| ECT2 | 10441 |
| MYH14 | 10431 |
| FAM135A | 10410 |
| NCKIPSD | 10395 |
| SPTBN1 | 10356 |
| YKT6 | 10349 |
| IL32 | 10276 |
| CEP97 | 10215 |
| ARFGAP3 | 10209 |
| ARHGEF10L | 10192 |
| CDC42SE2 | 10187 |
| H2AFX | 10131 |
| DSP | 10069 |
| PPP2R1A | 10064 |
| HMOX2 | 10061 |
| PKN1 | 10044 |
| ACBD5 | 10037 |
| MYH9 | 10036 |
| INCENP | 10005 |
| SGO2 | 9987 |
| CCDC88A | 9957 |
| CENPM | 9951 |
| ZNF512B | 9920 |
| UACA | 9918 |
| KIF18A | 9884 |
| KIF14 | 9870 |
| VAV3 | 9861 |
| FAF2 | 9859 |
| BIRC5 | 9771 |
| ALDH3A2 | 9706 |
| B9D2 | 9695 |
| STAM | 9665 |
| DLG4 | 9664 |
| ARHGEF9 | 9653 |
| PEAK1 | 9614 |
| PPP2CB | 9606 |
| PLK1 | 9548 |
| DIAPH3 | 9508 |
| ARAP3 | 9501 |
| ABI1 | 9492 |
| ARHGAP5 | 9487 |
| ARHGAP8 | 9485 |
| SEH1L | 9474 |
| DAAM1 | 9439 |
| ANLN | 9438 |
| ARPC1B | 9372 |
| HSP90AB1 | 9363 |
| ARHGAP21 | 9336 |
| ARHGEF26 | 9307 |
| SCAI | 9277 |
| PIK3R1 | 9259 |
| PTK2 | 9198 |
| SKA1 | 9144 |
| USP9X | 9136 |
| NCOA2 | 9072 |
| MAP3K11 | 9031 |
| POTEE | 9019 |
| CLASP2 | 8977 |
| CENPT | 8952 |
| DSG2 | 8936 |
| HGS | 8898 |
| ARHGAP33 | 8894 |
| ARHGEF39 | 8819 |
| ARHGAP27 | 8813 |
| SFN | 8812 |
| TWF1 | 8810 |
| MCAM | 8792 |
| VANGL1 | 8782 |
| KCTD3 | 8775 |
| ITGB1 | 8760 |
| PPP2R1B | 8759 |
| KLC1 | 8755 |
| UHRF1BP1L | 8723 |
| PPP1R12B | 8721 |
| RHOU | 8693 |
| CSK | 8692 |
| FMNL2 | 8666 |
| WDR81 | 8629 |
| CENPA | 8625 |
| TXNL1 | 8617 |
| ARHGAP29 | 8603 |
| AHCTF1 | 8598 |
| NOX3 | 8566 |
| ZW10 | 8564 |
| DOCK5 | 8523 |
| GRB7 | 8477 |
| TIAM1 | 8451 |
| TRIP10 | 8370 |
| GIT2 | 8347 |
| CKAP4 | 8327 |
| ARHGEF16 | 8317 |
| WDR91 | 8290 |
| CENPU | 8282 |
| BAIAP2L2 | 8278 |
| NCK2 | 8271 |
| MAD1L1 | 8264 |
| DYNC1LI2 | 8235 |
| PGRMC2 | 8168 |
| GFOD1 | 8080 |
| ARHGEF5 | 8063 |
| MFN1 | 8050 |
| STK38 | 8049 |
| FAM91A1 | 8041 |
| MAPRE1 | 8020 |
| KDM1A | 8018 |
| FRS2 | 8007 |
| CENPF | 7980 |
| NUP85 | 7946 |
| NUP98 | 7940 |
| NDUFA5 | 7919 |
| FERMT2 | 7814 |
| RHOT1 | 7793 |
| PARD6B | 7771 |
| DEF6 | 7696 |
| PPP1CB | 7685 |
| PLD2 | 7673 |
| ARHGEF3 | 7669 |
| ARHGEF25 | 7665 |
| DYNC1H1 | 7639 |
| GOLGA8R | 7631 |
| CPNE8 | 7624 |
| ROCK1 | 7591 |
| STIP1 | 7550 |
| SRC | 7516 |
| YWHAH | 7417 |
| GPS1 | 7406 |
| EMD | 7404 |
| KLC4 | 7401 |
| DOCK7 | 7277 |
| ARPC3 | 7237 |
| LMAN1 | 7220 |
| MYLK | 7150 |
| PPP1CC | 7149 |
| ARHGAP11A | 7148 |
| KLC2 | 7112 |
| WASF2 | 7096 |
| EFHD2 | 7090 |
| VANGL2 | 7088 |
| STBD1 | 7077 |
| FARP2 | 7020 |
| TAOK3 | 6995 |
| TRAK1 | 6949 |
| OBSCN | 6868 |
| TIAM2 | 6863 |
| VAPB | 6785 |
| KTN1 | 6769 |
| DOCK1 | 6760 |
| NSL1 | 6722 |
| LBR | 6666 |
| RANGAP1 | 6615 |
| WDR11 | 6588 |
| DBT | 6586 |
| BUB1 | 6536 |
| SWAP70 | 6466 |
| PKN3 | 6455 |
| SRF | 6447 |
| CUL3 | 6363 |
| GRB2 | 6346 |
| KCTD13 | 6315 |
| ARHGAP17 | 6310 |
| ABL2 | 6296 |
| CTNNB1 | 6288 |
| CKB | 6276 |
| ARHGAP26 | 6232 |
| PLEKHG4 | 6215 |
| SHKBP1 | 6194 |
| WIPF2 | 6174 |
| ARHGEF7 | 6055 |
| ARMCX3 | 6051 |
| LIN7B | 6030 |
| KLC3 | 5986 |
| SLC4A7 | 5963 |
| AKAP12 | 5962 |
| TAOK1 | 5951 |
| STAM2 | 5933 |
| PIN1 | 5922 |
| PIK3CA | 5849 |
| ARPC1A | 5822 |
| NCKAP1 | 5794 |
| DYNC1I2 | 5783 |
| ROCK2 | 5775 |
| RHOG | 5747 |
| TMOD3 | 5728 |
| AAAS | 5701 |
| SCRIB | 5488 |
| ARHGAP1 | 5462 |
| VAV2 | 5425 |
| NUP43 | 5410 |
| RHOF | 5403 |
| MTX1 | 5395 |
| CCNE1 | 5315 |
| PPP2R5C | 5293 |
| FGD1 | 5245 |
| RHOJ | 5241 |
| DYNC1LI1 | 5237 |
| MYL9 | 5218 |
| BCR | 5190 |
| MYO6 | 5156 |
| TAX1BP3 | 5154 |
| WASF3 | 5070 |
| PMF1 | 5043 |
| MSI2 | 5020 |
| FMNL1 | 4980 |
| MYH10 | 4942 |
| PHIP | 4905 |
| DYNLL1 | 4853 |
| ERBIN | 4809 |
| DIAPH2 | 4808 |
| MPP7 | 4807 |
| EVL | 4757 |
| PIK3R3 | 4734 |
| PRKCA | 4709 |
| DVL1 | 4696 |
| CPSF7 | 4652 |
| OSBPL11 | 4618 |
| SPTAN1 | 4610 |
| ARPC2 | 4575 |
| FAM169A | 4565 |
| ALS2 | 4492 |
| CDC42 | 4489 |
| ARHGAP9 | 4486 |
| JUP | 4478 |
| MAPK14 | 4391 |
| PPP2R5D | 4385 |
| CENPN | 4377 |
| CYBA | 4283 |
| ARHGEF19 | 4198 |
| FRS3 | 4125 |
| SYDE2 | 4108 |
| DDX39B | 4095 |
| FAM13A | 4071 |
| DOCK8 | 4066 |
| YWHAB | 4062 |
| DST | 4001 |
| ABL1 | 3944 |
| PICALM | 3941 |
| RASAL2 | 3937 |
| SGO1 | 3925 |
| LRRC41 | 3889 |
| XPO1 | 3824 |
| RHPN2 | 3804 |
| CYFIP1 | 3785 |
| PKP4 | 3674 |
| SRGAP1 | 3662 |
| NSFL1C | 3630 |
| SRGAP2 | 3627 |
| HNRNPC | 3563 |
| NDE1 | 3555 |
| CHN1 | 3467 |
| DOCK9 | 3436 |
| ARAP2 | 3353 |
| ARAP1 | 3351 |
| GOPC | 3212 |
| MUC13 | 3097 |
| STOM | 3093 |
| LIMK1 | 3082 |
| DNMBP | 3080 |
| ARPC5 | 3073 |
| CLASP1 | 3071 |
| NCK1 | 3010 |
| CCT7 | 2974 |
| SLITRK5 | 2858 |
| ACTR2 | 2855 |
| RAC3 | 2837 |
| RND1 | 2828 |
| ARHGAP12 | 2812 |
| PLEKHG6 | 2747 |
| PIK3R2 | 2728 |
| CENPP | 2725 |
| NUP133 | 2708 |
| MOSPD2 | 2673 |
| ARHGAP18 | 2628 |
| FLOT1 | 2624 |
| ARHGAP22 | 2602 |
| RHOD | 2596 |
| MEN1 | 2581 |
| ARFGAP2 | 2547 |
| TRA2B | 2539 |
| ARHGDIG | 2530 |
| WDR6 | 2528 |
| ABI2 | 2431 |
| FNBP1L | 2414 |
| DOCK4 | 2380 |
| CAPZB | 2376 |
| LRRC1 | 2299 |
| BUB3 | 2290 |
| FMNL3 | 2271 |
| MYO9A | 2252 |
| PIK3R4 | 2219 |
| ARHGEF12 | 2216 |
| TRAK2 | 2191 |
| PPP1R12A | 2182 |
| CDC42EP1 | 2171 |
| PLXNA1 | 2146 |
| PLXNB1 | 2132 |
| HSP90AA1 | 2096 |
| YWHAG | 2081 |
| RALGAPA1 | 2044 |
| RALBP1 | 2026 |
| PAK1 | 2021 |
| MYH11 | 1998 |
| NCKAP1L | 1980 |
| CTTN | 1934 |
| ARHGEF4 | 1931 |
| SOS1 | 1928 |
| MYO19 | 1909 |
| PLEKHG1 | 1905 |
| LEMD3 | 1868 |
| ELMO2 | 1854 |
| ARHGEF18 | 1850 |
| DVL2 | 1843 |
| ARHGAP4 | 1829 |
| SENP1 | 1811 |
| YWHAZ | 1810 |
| TPM4 | 1674 |
| HSPE1 | 1662 |
| CDKN1B | 1590 |
| TEX2 | 1573 |
| LAMTOR1 | 1557 |
| CENPL | 1495 |
| MTMR1 | 1468 |
| VAMP3 | 1415 |
| C1QBP | 1380 |
| CALM1 | 1340 |
| DOCK6 | 1298 |
| BAIAP2 | 1295 |
| PLEKHG5 | 1283 |
| PKN2 | 1213 |
| ARHGAP28 | 1191 |
| NDUFS3 | 1132 |
| ITSN2 | 1120 |
| STARD8 | 1115 |
| CCDC115 | 1075 |
| YWHAQ | 1061 |
| MCF2L | 1047 |
| RHOT2 | 1020 |
| FGD2 | 990 |
| SCFD1 | 960 |
| PLEKHG3 | 958 |
| ARHGAP40 | 861 |
| KALRN | 828 |
| ABCD3 | 821 |
| CENPO | 820 |
| PDPK1 | 782 |
| SRRM1 | 723 |
| NUP160 | 683 |
| STK10 | 642 |
| PPP2R5E | 554 |
| MAPK11 | 492 |
| ARHGAP10 | 474 |
| ABR | 434 |
| ARHGEF17 | 334 |
| RPS27 | 312 |
| ITSN1 | 311 |
| YWHAE | 253 |
| PAFAH1B1 | 237 |
| SH3BP1 | 196 |
| RHOH | 103 |
| RAC1 | 95 |
| ERCC6L | 86 |
| TPM3 | 71 |
| COPS4 | 51 |
| ARHGEF1 | 48 |
| NOXO1 | 21 |
| RANBP2 | 9 |
Cellular responses to stress
| 156 | |
|---|---|
| set | Cellular responses to stress |
| setSize | 633 |
| pANOVA | 0.000129 |
| s.dist | 0.0898 |
| p.adjustANOVA | 0.00594 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| HSPA5 | 14531 |
| CALR | 14529 |
| DNAJB11 | 14528 |
| HYOU1 | 14527 |
| HERPUD1 | 14524 |
| DNAJC3 | 14516 |
| HSP90B1 | 14514 |
| DNAJB9 | 14510 |
| TXNIP | 14509 |
| SYVN1 | 14485 |
| PDIA6 | 14482 |
| EDEM1 | 14479 |
| WFS1 | 14466 |
| ATP6V0B | 14422 |
| GFPT1 | 14406 |
| DDIT3 | 14401 |
| EIF2AK3 | 14371 |
| HM13 | 14368 |
| SOD2 | 14367 |
| FLCN | 14362 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HSPA5 | 14531 |
| CALR | 14529 |
| DNAJB11 | 14528 |
| HYOU1 | 14527 |
| HERPUD1 | 14524 |
| DNAJC3 | 14516 |
| HSP90B1 | 14514 |
| DNAJB9 | 14510 |
| TXNIP | 14509 |
| SYVN1 | 14485 |
| PDIA6 | 14482 |
| EDEM1 | 14479 |
| WFS1 | 14466 |
| ATP6V0B | 14422 |
| GFPT1 | 14406 |
| DDIT3 | 14401 |
| EIF2AK3 | 14371 |
| HM13 | 14368 |
| SOD2 | 14367 |
| FLCN | 14362 |
| RRAGC | 14345 |
| MAFK | 14318 |
| RPL36AL | 14313 |
| MYDGF | 14306 |
| SERP1 | 14288 |
| MT-CO3 | 14274 |
| ATF6 | 14261 |
| KDM6B | 14253 |
| WIPI1 | 14251 |
| ATP6V1D | 14228 |
| RPS19BP1 | 14217 |
| SHC1 | 14209 |
| ATP6V0D1 | 14206 |
| SSR1 | 14205 |
| FKBP14 | 14184 |
| SRPRB | 14181 |
| P4HB | 14170 |
| ERN1 | 14152 |
| CREB3L2 | 14080 |
| ATF5 | 14076 |
| SEC13 | 14049 |
| TXNRD1 | 14041 |
| TRIB3 | 14029 |
| HSPA13 | 14005 |
| TSPYL2 | 14002 |
| PPP1R15A | 13999 |
| FNIP1 | 13998 |
| EGLN2 | 13975 |
| NCOA6 | 13941 |
| RRAGD | 13938 |
| PPARA | 13906 |
| VCP | 13902 |
| HDGF | 13896 |
| PRDX1 | 13828 |
| PSMF1 | 13810 |
| UBE2C | 13793 |
| CRTC2 | 13780 |
| SCO2 | 13759 |
| ATP6V0E1 | 13731 |
| SESN2 | 13712 |
| LMNB1 | 13707 |
| NUP37 | 13706 |
| E2F1 | 13694 |
| HSPA9 | 13667 |
| COX20 | 13633 |
| HSPH1 | 13584 |
| EXOSC6 | 13547 |
| VHL | 13531 |
| DNAJC7 | 13527 |
| KEAP1 | 13510 |
| EP300 | 13485 |
| TATDN2 | 13480 |
| MAPKAPK2 | 13468 |
| PSME4 | 13450 |
| APOA1 | 13433 |
| PSMD2 | 13423 |
| GPX2 | 13379 |
| TPP1 | 13378 |
| RPA2 | 13354 |
| CBX2 | 13350 |
| EXTL1 | 13312 |
| POM121 | 13281 |
| DNAJB1 | 13228 |
| CHAC1 | 13119 |
| ATP6V1E1 | 13114 |
| NUP210 | 13025 |
| ATF2 | 12933 |
| TLN1 | 12872 |
| ATP6V0C | 12764 |
| HIRA | 12746 |
| SCMH1 | 12722 |
| POM121C | 12687 |
| MAPK3 | 12684 |
| CXXC1 | 12670 |
| ERF | 12637 |
| MEF2D | 12594 |
| CCNA2 | 12587 |
| AKT1S1 | 12584 |
| CEBPG | 12578 |
| AGO4 | 12561 |
| ADD1 | 12538 |
| MBTPS1 | 12523 |
| PSMD6 | 12502 |
| ABCC1 | 12501 |
| ATP6V1C2 | 12453 |
| MT-CO1 | 12380 |
| SIN3A | 12373 |
| RORA | 12360 |
| PPARGC1A | 12350 |
| UBN1 | 12306 |
| E2F2 | 12251 |
| MOV10 | 12217 |
| FKBP4 | 12213 |
| AGO3 | 12205 |
| PSMA2 | 12203 |
| MAP4K4 | 12181 |
| RPA3 | 12149 |
| MAPKAPK3 | 12147 |
| SEC31A | 12138 |
| LRPPRC | 12122 |
| PSMA1 | 12052 |
| ANAPC16 | 12018 |
| ATF4 | 11932 |
| DDX11 | 11907 |
| ANAPC7 | 11895 |
| PRKCD | 11872 |
| EZH2 | 11860 |
| SIRT1 | 11855 |
| ASNS | 11814 |
| ATP6V1B2 | 11744 |
| PSMC1 | 11724 |
| HIKESHI | 11695 |
| POT1 | 11678 |
| SLC38A9 | 11664 |
| PSMD3 | 11655 |
| CDC23 | 11639 |
| HSPB8 | 11600 |
| GRB10 | 11598 |
| FNIP2 | 11587 |
| CA9 | 11579 |
| NUP107 | 11561 |
| PSME2 | 11555 |
| ANAPC10 | 11551 |
| DYNLL2 | 11507 |
| MED1 | 11468 |
| AJUBA | 11454 |
| AQP8 | 11449 |
| NCF2 | 11446 |
| CREB3L3 | 11433 |
| SP1 | 11396 |
| NPAS2 | 11394 |
| NUP35 | 11387 |
| PSMD14 | 11371 |
| HSPA14 | 11362 |
| HDAC6 | 11333 |
| SKP2 | 11323 |
| XBP1 | 11302 |
| ATP6V1G1 | 11283 |
| PSMD1 | 11280 |
| CREB3L4 | 11259 |
| BAG3 | 11246 |
| LAMTOR5 | 11181 |
| TERF1 | 11145 |
| NUP205 | 11144 |
| RPL19 | 11094 |
| BAG5 | 11071 |
| NUP93 | 11067 |
| HMGA1 | 11043 |
| SOD1 | 10975 |
| EIF2S1 | 10961 |
| FOS | 10931 |
| ACTR1A | 10903 |
| DNAJB6 | 10856 |
| RPS7 | 10850 |
| PPP2R5B | 10834 |
| DCP2 | 10825 |
| ATP6V0E2 | 10798 |
| GSK3B | 10767 |
| HMGA2 | 10714 |
| UBA52 | 10707 |
| MAPK1 | 10705 |
| CDK4 | 10698 |
| CSNK2A1 | 10637 |
| COL4A6 | 10629 |
| COX5A | 10625 |
| RPL11 | 10624 |
| RPL10 | 10608 |
| ACTR10 | 10590 |
| RPS15 | 10567 |
| RPA1 | 10563 |
| NUP188 | 10521 |
| FAU | 10520 |
| DEPDC5 | 10518 |
| TACO1 | 10511 |
| RPL14 | 10500 |
| BACH1 | 10478 |
| CRTC3 | 10469 |
| ATP6V1C1 | 10444 |
| ANAPC15 | 10442 |
| PSMB9 | 10430 |
| HSPA12A | 10402 |
| ATR | 10396 |
| EPAS1 | 10387 |
| PSMB6 | 10326 |
| PSMC6 | 10307 |
| CDKN2D | 10296 |
| CAPZA1 | 10272 |
| GPX3 | 10217 |
| RRAGB | 10211 |
| PSMC4 | 10196 |
| TNRC6C | 10180 |
| SRPRA | 10175 |
| DNAJC2 | 10157 |
| RPS5 | 10135 |
| NUP88 | 10134 |
| H2AFX | 10131 |
| EXOSC5 | 10117 |
| FKBP5 | 10097 |
| HMOX2 | 10061 |
| NUP50 | 10047 |
| RPS11 | 9977 |
| NCOA1 | 9914 |
| RPS19 | 9909 |
| HSPA8 | 9895 |
| RPS28 | 9891 |
| PSMD9 | 9853 |
| CHD9 | 9842 |
| GCN1 | 9826 |
| EXOSC7 | 9819 |
| NR1D1 | 9818 |
| CREBRF | 9731 |
| PARN | 9715 |
| RBBP7 | 9712 |
| PSMD5 | 9676 |
| CSNK2A2 | 9641 |
| FABP1 | 9636 |
| NFYB | 9634 |
| BAG1 | 9631 |
| COX8A | 9591 |
| MAP2K4 | 9558 |
| SZT2 | 9557 |
| CAT | 9504 |
| SEH1L | 9474 |
| CTDSP2 | 9444 |
| EIF2S2 | 9437 |
| VEGFA | 9433 |
| SESN1 | 9414 |
| PSMD7 | 9371 |
| HSP90AB1 | 9363 |
| ATP6V1H | 9358 |
| PSMD10 | 9356 |
| NCOR2 | 9331 |
| WDR59 | 9316 |
| MAP2K7 | 9311 |
| RPLP1 | 9291 |
| MAPK7 | 9270 |
| NCOR1 | 9256 |
| PSMB7 | 9253 |
| NPRL2 | 9247 |
| TNIK | 9243 |
| CBX8 | 9242 |
| RPS12 | 9239 |
| COX7A2L | 9228 |
| CCS | 9214 |
| TFDP2 | 9210 |
| FBXL17 | 9200 |
| ST13 | 9142 |
| NUP155 | 9102 |
| EGLN1 | 9096 |
| HELZ2 | 9086 |
| RPL27A | 9081 |
| NCOA2 | 9072 |
| RPLP0 | 9067 |
| TERF2IP | 9056 |
| PHC1 | 9053 |
| CDK6 | 9023 |
| UBB | 9013 |
| PLA2G4B | 8953 |
| TNRC6B | 8904 |
| PSMA4 | 8902 |
| STAP2 | 8852 |
| BMI1 | 8838 |
| HIF1A | 8807 |
| RPL35A | 8797 |
| EEF1A1 | 8740 |
| CUL1 | 8725 |
| HMOX1 | 8715 |
| PSMD4 | 8670 |
| CAMK2A | 8669 |
| PSMC5 | 8646 |
| ATP6V1B1 | 8635 |
| RPL30 | 8630 |
| RAD50 | 8623 |
| RXRA | 8607 |
| NBN | 8606 |
| CBX4 | 8580 |
| MAPKAPK5 | 8556 |
| COX4I1 | 8531 |
| RPS9 | 8515 |
| ID1 | 8511 |
| TERF2 | 8496 |
| KPTN | 8495 |
| NR3C1 | 8476 |
| COX14 | 8475 |
| WDR24 | 8468 |
| UBE2D3 | 8449 |
| HIF3A | 8437 |
| IMPACT | 8414 |
| RPL18 | 8381 |
| DCTN2 | 8375 |
| CSNK2B | 8368 |
| SERPINH1 | 8349 |
| RAE1 | 8335 |
| CUL7 | 8310 |
| IGFBP1 | 8301 |
| TINF2 | 8275 |
| DYNC1LI2 | 8235 |
| CREBBP | 8214 |
| RPL26L1 | 8188 |
| COX7B | 8175 |
| AGO1 | 8173 |
| PSMD12 | 8163 |
| HIF1AN | 8161 |
| RPS6KA1 | 8159 |
| RPS29 | 8133 |
| RPL6 | 8132 |
| IGFBP7 | 8108 |
| STAT3 | 8078 |
| PSME3 | 8052 |
| KLHDC3 | 8036 |
| CDKN2C | 8034 |
| CITED2 | 8029 |
| ATP6V1A | 7965 |
| NUP85 | 7946 |
| NUP98 | 7940 |
| RHEB | 7936 |
| WTIP | 7931 |
| EP400 | 7921 |
| NPRL3 | 7917 |
| ACADVL | 7903 |
| LMNA | 7854 |
| RBX1 | 7850 |
| COX19 | 7838 |
| CDK2 | 7809 |
| GSK3A | 7787 |
| MTOR | 7785 |
| MRE11 | 7780 |
| DEDD2 | 7779 |
| EIF2S3 | 7757 |
| CREB3 | 7725 |
| RING1 | 7710 |
| DCTN5 | 7690 |
| SIN3B | 7646 |
| DYNC1H1 | 7639 |
| BAG4 | 7633 |
| TXN | 7626 |
| CDKN1A | 7569 |
| STIP1 | 7550 |
| RPL28 | 7500 |
| ANAPC5 | 7485 |
| HSPA4L | 7475 |
| GSR | 7463 |
| RPSA | 7435 |
| ASF1A | 7415 |
| NFKB1 | 7409 |
| RPL8 | 7307 |
| RPS4X | 7297 |
| RPS2 | 7293 |
| EXOSC3 | 7270 |
| RPL29 | 7265 |
| RPL32 | 7263 |
| RPL36 | 7221 |
| COX18 | 7215 |
| RPL37 | 7194 |
| EXOSC2 | 7192 |
| RPS17 | 7104 |
| PTGES3 | 7103 |
| UBE2E1 | 7102 |
| PHC2 | 7072 |
| HSPA6 | 7061 |
| RPS24 | 7060 |
| CDKN2A | 7056 |
| MAP2K3 | 7038 |
| MBTPS2 | 7019 |
| SH3BP4 | 7014 |
| ATOX1 | 6974 |
| RBBP4 | 6938 |
| CXCL8 | 6916 |
| CCAR2 | 6864 |
| RPS14 | 6851 |
| DNAJA2 | 6843 |
| EXTL3 | 6822 |
| ETS1 | 6791 |
| UBE2D1 | 6734 |
| CARM1 | 6725 |
| ZBTB17 | 6703 |
| EXOSC1 | 6667 |
| RPS27L | 6664 |
| COX6B1 | 6617 |
| RPS10 | 6612 |
| SEM1 | 6566 |
| HSPA2 | 6538 |
| COX6A1 | 6487 |
| EXTL2 | 6440 |
| PSMA3 | 6422 |
| NUP54 | 6371 |
| CUL3 | 6363 |
| PTK6 | 6358 |
| EXOSC9 | 6333 |
| RPS6KA3 | 6316 |
| HBA1 | 6302 |
| RPS15A | 6295 |
| SCO1 | 6294 |
| ELOB | 6272 |
| RPL7 | 6223 |
| RPL34 | 6203 |
| EXOSC4 | 6193 |
| APOB | 6172 |
| JUN | 6103 |
| PSMD8 | 6091 |
| GPX1 | 6089 |
| RPS21 | 6082 |
| EIF2AK1 | 6069 |
| RPS16 | 6026 |
| RPS3 | 5985 |
| RPL13A | 5970 |
| ALB | 5965 |
| RPLP2 | 5950 |
| RPL35 | 5927 |
| ACD | 5857 |
| DYNC1I2 | 5783 |
| RPS27A | 5776 |
| LIMD1 | 5738 |
| CRTC1 | 5705 |
| AAAS | 5701 |
| MAPK10 | 5681 |
| PSMA5 | 5657 |
| MIOS | 5610 |
| CBX6 | 5608 |
| RPL23A | 5592 |
| RPL10A | 5584 |
| RPS6 | 5569 |
| RPL36A | 5542 |
| RPS18 | 5504 |
| RPL41 | 5472 |
| RELA | 5468 |
| LAMTOR3 | 5467 |
| NUP43 | 5410 |
| RPS13 | 5366 |
| TFDP1 | 5361 |
| PSMD13 | 5353 |
| RPL4 | 5324 |
| MDM4 | 5318 |
| CCNE1 | 5315 |
| GPX7 | 5287 |
| DYNC1LI1 | 5237 |
| NUP153 | 5230 |
| NFYA | 5142 |
| RPS23 | 5114 |
| RPL37A | 5072 |
| RRAGA | 5038 |
| HSF1 | 5003 |
| EGLN3 | 5001 |
| PSMC2 | 4948 |
| MAP2K6 | 4868 |
| PSME1 | 4861 |
| DYNLL1 | 4853 |
| ATF3 | 4803 |
| DNAJA1 | 4793 |
| RNF2 | 4732 |
| RPL39 | 4713 |
| RPL18A | 4649 |
| RPL7A | 4625 |
| NUP58 | 4603 |
| EED | 4581 |
| ETS2 | 4533 |
| TNFRSF21 | 4491 |
| CABIN1 | 4476 |
| SMARCD3 | 4455 |
| MAPK14 | 4391 |
| RPS4Y1 | 4388 |
| MINK1 | 4372 |
| NFE2L2 | 4363 |
| CYBA | 4283 |
| RPL27 | 4268 |
| TGS1 | 4181 |
| CAMK2G | 4176 |
| ITFG2 | 4172 |
| RPL22 | 4170 |
| CCNE2 | 4152 |
| TP53 | 4144 |
| ATP7A | 4123 |
| RAI1 | 4118 |
| EPO | 4044 |
| DCTN4 | 3979 |
| NUP214 | 3957 |
| PSMB3 | 3928 |
| RPL23 | 3923 |
| ANAPC1 | 3900 |
| UBE2S | 3839 |
| XPO1 | 3824 |
| RPL24 | 3686 |
| PSMB2 | 3678 |
| MLST8 | 3677 |
| RPL38 | 3652 |
| HSPA1A | 3603 |
| LAMTOR4 | 3602 |
| TNRC6A | 3580 |
| RPS20 | 3578 |
| RPL26 | 3560 |
| MAPK9 | 3449 |
| EHMT1 | 3422 |
| CLOCK | 3360 |
| CAMK2D | 3358 |
| CDKN2B | 3352 |
| ANAPC2 | 3349 |
| DCTN1 | 3338 |
| TBL1X | 3308 |
| ARFGAP1 | 3224 |
| DIS3 | 3190 |
| CAPZA2 | 3143 |
| ANAPC11 | 3134 |
| KAT5 | 3115 |
| CDC27 | 3103 |
| PSMC3 | 3070 |
| NDC1 | 3023 |
| COX11 | 3007 |
| NR3C2 | 2999 |
| ATM | 2965 |
| EIF2AK4 | 2950 |
| COX7C | 2931 |
| BLVRA | 2921 |
| DCTN3 | 2887 |
| PREB | 2868 |
| TBL1XR1 | 2795 |
| RPL21 | 2755 |
| HSBP1 | 2726 |
| NUP133 | 2708 |
| LY96 | 2689 |
| RPL15 | 2637 |
| PRDX5 | 2560 |
| BAG2 | 2521 |
| GOSR2 | 2441 |
| CAPZB | 2376 |
| RPL3 | 2369 |
| RPS6KA2 | 2339 |
| PSMB4 | 2330 |
| CDC16 | 2309 |
| CEBPB | 2300 |
| RPL17 | 2280 |
| RPS8 | 2190 |
| HSP90AA1 | 2096 |
| PSMB1 | 2062 |
| SULT1A3 | 2038 |
| KHSRP | 2029 |
| RPL12 | 2000 |
| ARNT | 1996 |
| PRDX2 | 1951 |
| MDM2 | 1942 |
| KDELR3 | 1922 |
| RPS25 | 1901 |
| UBE2D2 | 1857 |
| COX16 | 1851 |
| CRYAB | 1848 |
| PSMA7 | 1820 |
| HSPA4 | 1816 |
| MRPL18 | 1806 |
| ATP6V1F | 1771 |
| SLC46A1 | 1702 |
| PHC3 | 1660 |
| BLVRB | 1602 |
| CDKN1B | 1590 |
| LAMTOR1 | 1557 |
| UBC | 1551 |
| ATP6V0D2 | 1494 |
| GPX8 | 1486 |
| PSMB5 | 1484 |
| HIGD1A | 1427 |
| RPL13 | 1426 |
| MAPK8 | 1418 |
| MT-CO2 | 1414 |
| NFYC | 1395 |
| COX5B | 1393 |
| ATP6V1G2 | 1360 |
| ELOC | 1265 |
| BMT2 | 1250 |
| PDIA5 | 1130 |
| SKP1 | 1117 |
| NRIP1 | 1114 |
| TPR | 1105 |
| CYCS | 1098 |
| ATP6V1E2 | 1090 |
| RPL5 | 1001 |
| CREB1 | 935 |
| EXOSC8 | 928 |
| RB1 | 925 |
| PSMD11 | 879 |
| E2F3 | 876 |
| PSMB10 | 838 |
| RPS26 | 827 |
| RPTOR | 803 |
| NDUFA4 | 795 |
| EHMT2 | 784 |
| ARNTL | 732 |
| CUL2 | 703 |
| NUP160 | 683 |
| DCTN6 | 666 |
| SUZ12 | 664 |
| COX6C | 661 |
| RPL31 | 638 |
| SURF1 | 631 |
| NUP62 | 618 |
| TXNRD2 | 603 |
| ANAPC4 | 595 |
| NUDT2 | 589 |
| RPL9 | 509 |
| TXN2 | 499 |
| MAPK11 | 492 |
| RPL22L1 | 439 |
| ERO1A | 403 |
| CDC26 | 402 |
| FZR1 | 397 |
| YIF1A | 381 |
| RPS3A | 369 |
| TCIRG1 | 348 |
| PRDX3 | 321 |
| RPS27 | 312 |
| LAMTOR2 | 299 |
| PSMA6 | 261 |
| YWHAE | 253 |
| PRDX6 | 106 |
| HDAC3 | 84 |
| RANBP2 | 9 |
Apoptotic execution phase
| 70 | |
|---|---|
| set | Apoptotic execution phase |
| setSize | 39 |
| pANOVA | 0.000139 |
| s.dist | 0.353 |
| p.adjustANOVA | 0.00616 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CDH1 | 14202 |
| KPNA1 | 13876 |
| LMNB1 | 13707 |
| HMGB2 | 13614 |
| DFFA | 13559 |
| PLEC | 13537 |
| CLSPN | 13484 |
| MAPT | 13405 |
| KPNB1 | 13324 |
| FNTA | 13142 |
| STK26 | 12952 |
| BCAP31 | 12840 |
| ADD1 | 12538 |
| PRKCD | 11872 |
| TJP2 | 11851 |
| CASP3 | 11107 |
| DNM1L | 10670 |
| HMGB1 | 10552 |
| PAK2 | 10458 |
| DFFB | 10294 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CDH1 | 14202 |
| KPNA1 | 13876 |
| LMNB1 | 13707 |
| HMGB2 | 13614 |
| DFFA | 13559 |
| PLEC | 13537 |
| CLSPN | 13484 |
| MAPT | 13405 |
| KPNB1 | 13324 |
| FNTA | 13142 |
| STK26 | 12952 |
| BCAP31 | 12840 |
| ADD1 | 12538 |
| PRKCD | 11872 |
| TJP2 | 11851 |
| CASP3 | 11107 |
| DNM1L | 10670 |
| HMGB1 | 10552 |
| PAK2 | 10458 |
| DFFB | 10294 |
| TJP1 | 10173 |
| DSP | 10069 |
| CASP7 | 9780 |
| STK24 | 9682 |
| PTK2 | 9198 |
| DSG2 | 8936 |
| ACIN1 | 8243 |
| LMNA | 7854 |
| CASP6 | 7839 |
| GAS2 | 7602 |
| ROCK1 | 7591 |
| DBNL | 6490 |
| CTNNB1 | 6288 |
| CASP8 | 6085 |
| SPTAN1 | 4610 |
| OCLN | 3996 |
| APC | 3716 |
| GSN | 2952 |
| BIRC2 | 1007 |
Signaling by Rho GTPases
| 1148 | |
|---|---|
| set | Signaling by Rho GTPases |
| setSize | 551 |
| pANOVA | 0.000157 |
| s.dist | 0.0947 |
| p.adjustANOVA | 0.00678 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| STEAP3 | 14327 |
| ARHGEF2 | 14307 |
| RHOQ | 14296 |
| DVL3 | 14293 |
| JAG1 | 14259 |
| ARHGEF28 | 14232 |
| CDH1 | 14202 |
| ARHGAP32 | 14201 |
| PLD1 | 14191 |
| RHOBTB2 | 14141 |
| EPHA2 | 14124 |
| ACTG1 | 14090 |
| GOLGA3 | 14085 |
| FLNA | 14081 |
| SEC13 | 14049 |
| RHOC | 13943 |
| VCP | 13902 |
| NDC80 | 13840 |
| ACTN1 | 13824 |
| FLOT2 | 13811 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| STEAP3 | 14327 |
| ARHGEF2 | 14307 |
| RHOQ | 14296 |
| DVL3 | 14293 |
| JAG1 | 14259 |
| ARHGEF28 | 14232 |
| CDH1 | 14202 |
| ARHGAP32 | 14201 |
| PLD1 | 14191 |
| RHOBTB2 | 14141 |
| EPHA2 | 14124 |
| ACTG1 | 14090 |
| GOLGA3 | 14085 |
| FLNA | 14081 |
| SEC13 | 14049 |
| RHOC | 13943 |
| VCP | 13902 |
| NDC80 | 13840 |
| ACTN1 | 13824 |
| FLOT2 | 13811 |
| NUDC | 13808 |
| EMC3 | 13805 |
| MYL12B | 13785 |
| TFRC | 13755 |
| KIF5A | 13752 |
| LMNB1 | 13707 |
| NUP37 | 13706 |
| AKAP13 | 13699 |
| DLC1 | 13698 |
| GNA13 | 13689 |
| TUBA1B | 13681 |
| RAPGEF1 | 13680 |
| PRKCZ | 13676 |
| NF2 | 13642 |
| KNL1 | 13621 |
| MAD2L1 | 13616 |
| WASL | 13611 |
| NGEF | 13605 |
| ESYT1 | 13601 |
| VRK2 | 13580 |
| SEMA4F | 13579 |
| ANKLE2 | 13567 |
| FGD3 | 13525 |
| CENPK | 13518 |
| SPC24 | 13498 |
| ANKRD26 | 13489 |
| NUF2 | 13470 |
| ARHGAP35 | 13445 |
| BUB1B | 13431 |
| TMPO | 13363 |
| MYL6 | 13325 |
| FNBP1 | 13314 |
| TMEM59 | 13311 |
| MIS12 | 13304 |
| IQGAP3 | 13282 |
| CDC42EP4 | 13265 |
| DSN1 | 13258 |
| BAIAP2L1 | 13253 |
| AURKB | 13190 |
| ARHGAP39 | 13184 |
| PFN2 | 13179 |
| PFN1 | 13146 |
| CPD | 13139 |
| OCRL | 13103 |
| CDC25C | 13084 |
| LCK | 13069 |
| RBBP6 | 13058 |
| ATP6AP1 | 13046 |
| PTK2B | 13043 |
| CLTC | 13017 |
| SH3RF1 | 13005 |
| SPEN | 12976 |
| SRGAP3 | 12970 |
| ARHGAP19 | 12886 |
| SHMT2 | 12864 |
| SPDL1 | 12856 |
| BCAP31 | 12840 |
| ARPC4 | 12778 |
| KNTC1 | 12758 |
| KIDINS220 | 12710 |
| CDCA8 | 12700 |
| MAPK3 | 12684 |
| CKAP5 | 12651 |
| STARD13 | 12646 |
| RHPN1 | 12589 |
| DDRGK1 | 12585 |
| SLC1A5 | 12542 |
| RASGRF2 | 12510 |
| PRC1 | 12500 |
| CLIP1 | 12494 |
| LETM1 | 12482 |
| CDC42BPA | 12468 |
| SPATA13 | 12459 |
| CCT2 | 12444 |
| MYO9B | 12432 |
| SKA2 | 12421 |
| CCT6A | 12336 |
| ARHGEF40 | 12329 |
| UBXN11 | 12284 |
| RTKN | 12273 |
| KIF2A | 12231 |
| RAB7A | 12220 |
| DIAPH1 | 12211 |
| ITGB3BP | 12199 |
| LIMK2 | 12193 |
| WHAMM | 12191 |
| FGD4 | 12166 |
| OPHN1 | 12089 |
| PPP2R5A | 12088 |
| CFL1 | 12075 |
| NET1 | 12058 |
| WASF1 | 12021 |
| RCC2 | 12011 |
| TOR1AIP1 | 11985 |
| PLXND1 | 11963 |
| SNAP23 | 11956 |
| SOWAHC | 11934 |
| IQGAP1 | 11931 |
| NDEL1 | 11904 |
| ZWILCH | 11891 |
| DLG5 | 11889 |
| CENPH | 11884 |
| PRKCD | 11872 |
| ARHGAP42 | 11866 |
| HINT2 | 11856 |
| TJP2 | 11851 |
| CYFIP2 | 11850 |
| CCP110 | 11807 |
| GIT1 | 11767 |
| CTNNA1 | 11711 |
| DEPDC1B | 11636 |
| ARHGAP44 | 11618 |
| FAM13B | 11613 |
| SH3PXD2A | 11583 |
| ARHGAP11B | 11580 |
| ANKFY1 | 11567 |
| CDC42EP2 | 11566 |
| NUP107 | 11561 |
| RHOB | 11537 |
| MTR | 11525 |
| DYNLL2 | 11507 |
| CIT | 11482 |
| NCF2 | 11446 |
| BRK1 | 11428 |
| TNFAIP1 | 11426 |
| KIF5B | 11419 |
| TMEM87A | 11413 |
| NISCH | 11403 |
| SOS2 | 11402 |
| ZWINT | 11400 |
| KIF2C | 11386 |
| RHOBTB1 | 11372 |
| CENPI | 11351 |
| ARL13B | 11337 |
| ARHGDIA | 11324 |
| PAK4 | 11295 |
| CDC42BPB | 11293 |
| PARD6A | 11269 |
| TRIO | 11264 |
| IQGAP2 | 11231 |
| CENPQ | 11227 |
| CHN2 | 11204 |
| STX5 | 11191 |
| ACTR3 | 11186 |
| RHOA | 11182 |
| FARP1 | 11169 |
| ARHGEF11 | 11110 |
| RNF20 | 11085 |
| GMIP | 11044 |
| SYDE1 | 11040 |
| RBMX | 11027 |
| PIK3C3 | 11026 |
| RACGAP1 | 10990 |
| CDC37 | 10941 |
| PPP2CA | 10917 |
| COPS2 | 10902 |
| WWP2 | 10881 |
| KDM4C | 10878 |
| SLK | 10872 |
| PPP2R5B | 10834 |
| SAMM50 | 10805 |
| ADD3 | 10801 |
| DBN1 | 10764 |
| CENPC | 10756 |
| CDC20 | 10732 |
| MAPK1 | 10705 |
| PLEKHG2 | 10691 |
| ACTB | 10683 |
| ZAP70 | 10613 |
| CENPE | 10538 |
| RRAS2 | 10503 |
| PAK2 | 10458 |
| ARHGAP23 | 10454 |
| NOXA1 | 10451 |
| ECT2 | 10441 |
| MYH14 | 10431 |
| FAM135A | 10410 |
| NCKIPSD | 10395 |
| SPTBN1 | 10356 |
| YKT6 | 10349 |
| IL32 | 10276 |
| CEP97 | 10215 |
| ARFGAP3 | 10209 |
| ARHGEF10L | 10192 |
| CDC42SE2 | 10187 |
| H2AFX | 10131 |
| DSP | 10069 |
| PPP2R1A | 10064 |
| HMOX2 | 10061 |
| PKN1 | 10044 |
| ACBD5 | 10037 |
| MYH9 | 10036 |
| INCENP | 10005 |
| SGO2 | 9987 |
| CCDC88A | 9957 |
| CENPM | 9951 |
| ZNF512B | 9920 |
| UACA | 9918 |
| KIF18A | 9884 |
| KIF14 | 9870 |
| VAV3 | 9861 |
| FAF2 | 9859 |
| BIRC5 | 9771 |
| ALDH3A2 | 9706 |
| B9D2 | 9695 |
| STAM | 9665 |
| DLG4 | 9664 |
| ARHGEF9 | 9653 |
| PEAK1 | 9614 |
| PPP2CB | 9606 |
| PLK1 | 9548 |
| DIAPH3 | 9508 |
| ARAP3 | 9501 |
| ABI1 | 9492 |
| ARHGAP5 | 9487 |
| ARHGAP8 | 9485 |
| SEH1L | 9474 |
| DAAM1 | 9439 |
| ANLN | 9438 |
| ARPC1B | 9372 |
| HSP90AB1 | 9363 |
| ARHGAP21 | 9336 |
| ARHGEF26 | 9307 |
| SCAI | 9277 |
| PIK3R1 | 9259 |
| PTK2 | 9198 |
| SKA1 | 9144 |
| USP9X | 9136 |
| NCOA2 | 9072 |
| MAP3K11 | 9031 |
| POTEE | 9019 |
| CLASP2 | 8977 |
| CENPT | 8952 |
| DSG2 | 8936 |
| HGS | 8898 |
| ARHGAP33 | 8894 |
| ARHGEF39 | 8819 |
| ARHGAP27 | 8813 |
| SFN | 8812 |
| TWF1 | 8810 |
| MCAM | 8792 |
| VANGL1 | 8782 |
| KCTD3 | 8775 |
| ITGB1 | 8760 |
| PPP2R1B | 8759 |
| KLC1 | 8755 |
| UHRF1BP1L | 8723 |
| PPP1R12B | 8721 |
| RHOU | 8693 |
| CSK | 8692 |
| FMNL2 | 8666 |
| WDR81 | 8629 |
| CENPA | 8625 |
| TXNL1 | 8617 |
| ARHGAP29 | 8603 |
| AHCTF1 | 8598 |
| NOX3 | 8566 |
| ZW10 | 8564 |
| DOCK5 | 8523 |
| GRB7 | 8477 |
| TIAM1 | 8451 |
| TRIP10 | 8370 |
| GIT2 | 8347 |
| CKAP4 | 8327 |
| ARHGEF16 | 8317 |
| WDR91 | 8290 |
| CENPU | 8282 |
| BAIAP2L2 | 8278 |
| NCK2 | 8271 |
| MAD1L1 | 8264 |
| DYNC1LI2 | 8235 |
| PGRMC2 | 8168 |
| GFOD1 | 8080 |
| ARHGEF5 | 8063 |
| STK38 | 8049 |
| FAM91A1 | 8041 |
| MAPRE1 | 8020 |
| KDM1A | 8018 |
| FRS2 | 8007 |
| CENPF | 7980 |
| NUP85 | 7946 |
| NUP98 | 7940 |
| NDUFA5 | 7919 |
| FERMT2 | 7814 |
| PARD6B | 7771 |
| DEF6 | 7696 |
| PPP1CB | 7685 |
| PLD2 | 7673 |
| ARHGEF3 | 7669 |
| ARHGEF25 | 7665 |
| DYNC1H1 | 7639 |
| GOLGA8R | 7631 |
| CPNE8 | 7624 |
| ROCK1 | 7591 |
| STIP1 | 7550 |
| SRC | 7516 |
| YWHAH | 7417 |
| GPS1 | 7406 |
| EMD | 7404 |
| KLC4 | 7401 |
| DOCK7 | 7277 |
| ARPC3 | 7237 |
| LMAN1 | 7220 |
| MYLK | 7150 |
| PPP1CC | 7149 |
| ARHGAP11A | 7148 |
| KLC2 | 7112 |
| WASF2 | 7096 |
| EFHD2 | 7090 |
| VANGL2 | 7088 |
| STBD1 | 7077 |
| FARP2 | 7020 |
| TAOK3 | 6995 |
| OBSCN | 6868 |
| TIAM2 | 6863 |
| VAPB | 6785 |
| KTN1 | 6769 |
| DOCK1 | 6760 |
| NSL1 | 6722 |
| LBR | 6666 |
| RANGAP1 | 6615 |
| WDR11 | 6588 |
| DBT | 6586 |
| BUB1 | 6536 |
| SWAP70 | 6466 |
| PKN3 | 6455 |
| SRF | 6447 |
| CUL3 | 6363 |
| GRB2 | 6346 |
| KCTD13 | 6315 |
| ARHGAP17 | 6310 |
| ABL2 | 6296 |
| CTNNB1 | 6288 |
| CKB | 6276 |
| ARHGAP26 | 6232 |
| PLEKHG4 | 6215 |
| SHKBP1 | 6194 |
| WIPF2 | 6174 |
| ARHGEF7 | 6055 |
| ARMCX3 | 6051 |
| LIN7B | 6030 |
| KLC3 | 5986 |
| SLC4A7 | 5963 |
| AKAP12 | 5962 |
| TAOK1 | 5951 |
| STAM2 | 5933 |
| PIN1 | 5922 |
| PIK3CA | 5849 |
| ARPC1A | 5822 |
| NCKAP1 | 5794 |
| DYNC1I2 | 5783 |
| ROCK2 | 5775 |
| RHOG | 5747 |
| TMOD3 | 5728 |
| AAAS | 5701 |
| SCRIB | 5488 |
| ARHGAP1 | 5462 |
| VAV2 | 5425 |
| NUP43 | 5410 |
| RHOF | 5403 |
| MTX1 | 5395 |
| PPP2R5C | 5293 |
| FGD1 | 5245 |
| RHOJ | 5241 |
| DYNC1LI1 | 5237 |
| MYL9 | 5218 |
| BCR | 5190 |
| MYO6 | 5156 |
| TAX1BP3 | 5154 |
| WASF3 | 5070 |
| PMF1 | 5043 |
| MSI2 | 5020 |
| FMNL1 | 4980 |
| MYH10 | 4942 |
| PHIP | 4905 |
| DYNLL1 | 4853 |
| ERBIN | 4809 |
| DIAPH2 | 4808 |
| MPP7 | 4807 |
| EVL | 4757 |
| PIK3R3 | 4734 |
| PRKCA | 4709 |
| DVL1 | 4696 |
| CPSF7 | 4652 |
| OSBPL11 | 4618 |
| SPTAN1 | 4610 |
| ARPC2 | 4575 |
| FAM169A | 4565 |
| ALS2 | 4492 |
| CDC42 | 4489 |
| ARHGAP9 | 4486 |
| JUP | 4478 |
| MAPK14 | 4391 |
| PPP2R5D | 4385 |
| CENPN | 4377 |
| CYBA | 4283 |
| ARHGEF19 | 4198 |
| FRS3 | 4125 |
| SYDE2 | 4108 |
| DDX39B | 4095 |
| FAM13A | 4071 |
| DOCK8 | 4066 |
| YWHAB | 4062 |
| DST | 4001 |
| ABL1 | 3944 |
| PICALM | 3941 |
| RASAL2 | 3937 |
| SGO1 | 3925 |
| XPO1 | 3824 |
| RHPN2 | 3804 |
| CYFIP1 | 3785 |
| PKP4 | 3674 |
| SRGAP1 | 3662 |
| NSFL1C | 3630 |
| SRGAP2 | 3627 |
| HNRNPC | 3563 |
| NDE1 | 3555 |
| CHN1 | 3467 |
| DOCK9 | 3436 |
| ARAP2 | 3353 |
| ARAP1 | 3351 |
| GOPC | 3212 |
| MUC13 | 3097 |
| STOM | 3093 |
| LIMK1 | 3082 |
| DNMBP | 3080 |
| ARPC5 | 3073 |
| CLASP1 | 3071 |
| NCK1 | 3010 |
| CCT7 | 2974 |
| SLITRK5 | 2858 |
| ACTR2 | 2855 |
| RAC3 | 2837 |
| RND1 | 2828 |
| ARHGAP12 | 2812 |
| PLEKHG6 | 2747 |
| PIK3R2 | 2728 |
| CENPP | 2725 |
| NUP133 | 2708 |
| MOSPD2 | 2673 |
| ARHGAP18 | 2628 |
| FLOT1 | 2624 |
| ARHGAP22 | 2602 |
| RHOD | 2596 |
| MEN1 | 2581 |
| ARFGAP2 | 2547 |
| TRA2B | 2539 |
| ARHGDIG | 2530 |
| WDR6 | 2528 |
| ABI2 | 2431 |
| FNBP1L | 2414 |
| DOCK4 | 2380 |
| CAPZB | 2376 |
| LRRC1 | 2299 |
| BUB3 | 2290 |
| FMNL3 | 2271 |
| MYO9A | 2252 |
| PIK3R4 | 2219 |
| ARHGEF12 | 2216 |
| PPP1R12A | 2182 |
| CDC42EP1 | 2171 |
| PLXNA1 | 2146 |
| PLXNB1 | 2132 |
| HSP90AA1 | 2096 |
| YWHAG | 2081 |
| RALGAPA1 | 2044 |
| RALBP1 | 2026 |
| PAK1 | 2021 |
| MYH11 | 1998 |
| NCKAP1L | 1980 |
| CTTN | 1934 |
| ARHGEF4 | 1931 |
| SOS1 | 1928 |
| PLEKHG1 | 1905 |
| LEMD3 | 1868 |
| ELMO2 | 1854 |
| ARHGEF18 | 1850 |
| DVL2 | 1843 |
| ARHGAP4 | 1829 |
| SENP1 | 1811 |
| YWHAZ | 1810 |
| TPM4 | 1674 |
| HSPE1 | 1662 |
| CDKN1B | 1590 |
| TEX2 | 1573 |
| LAMTOR1 | 1557 |
| CENPL | 1495 |
| MTMR1 | 1468 |
| VAMP3 | 1415 |
| C1QBP | 1380 |
| CALM1 | 1340 |
| DOCK6 | 1298 |
| BAIAP2 | 1295 |
| PLEKHG5 | 1283 |
| PKN2 | 1213 |
| ARHGAP28 | 1191 |
| NDUFS3 | 1132 |
| ITSN2 | 1120 |
| STARD8 | 1115 |
| CCDC115 | 1075 |
| YWHAQ | 1061 |
| MCF2L | 1047 |
| FGD2 | 990 |
| SCFD1 | 960 |
| PLEKHG3 | 958 |
| ARHGAP40 | 861 |
| KALRN | 828 |
| ABCD3 | 821 |
| CENPO | 820 |
| PDPK1 | 782 |
| SRRM1 | 723 |
| NUP160 | 683 |
| STK10 | 642 |
| PPP2R5E | 554 |
| MAPK11 | 492 |
| ARHGAP10 | 474 |
| ABR | 434 |
| ARHGEF17 | 334 |
| RPS27 | 312 |
| ITSN1 | 311 |
| YWHAE | 253 |
| PAFAH1B1 | 237 |
| SH3BP1 | 196 |
| RHOH | 103 |
| RAC1 | 95 |
| ERCC6L | 86 |
| TPM3 | 71 |
| COPS4 | 51 |
| ARHGEF1 | 48 |
| NOXO1 | 21 |
| RANBP2 | 9 |
Plasma lipoprotein remodeling
| 800 | |
|---|---|
| set | Plasma lipoprotein remodeling |
| setSize | 29 |
| pANOVA | 0.000174 |
| s.dist | 0.403 |
| p.adjustANOVA | 0.00728 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| LIPG | 14461 |
| APOC3 | 14431 |
| P4HB | 14170 |
| FURIN | 13851 |
| LCAT | 13483 |
| APOA1 | 13433 |
| ANGPTL4 | 13342 |
| APOA2 | 13191 |
| LIPC | 12986 |
| MBTPS1 | 12523 |
| MTTP | 11924 |
| CREB3L3 | 11433 |
| ANGPTL8 | 10936 |
| LMF1 | 10661 |
| FGF21 | 10580 |
| CIDEC | 10542 |
| PLTP | 10314 |
| PCSK6 | 10075 |
| APOC2 | 9992 |
| APOF | 8633 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| LIPG | 14461 |
| APOC3 | 14431 |
| P4HB | 14170 |
| FURIN | 13851 |
| LCAT | 13483 |
| APOA1 | 13433 |
| ANGPTL4 | 13342 |
| APOA2 | 13191 |
| LIPC | 12986 |
| MBTPS1 | 12523 |
| MTTP | 11924 |
| CREB3L3 | 11433 |
| ANGPTL8 | 10936 |
| LMF1 | 10661 |
| FGF21 | 10580 |
| CIDEC | 10542 |
| PLTP | 10314 |
| PCSK6 | 10075 |
| APOC2 | 9992 |
| APOF | 8633 |
| APOA5 | 7816 |
| APOE | 7759 |
| LMF2 | 7243 |
| MBTPS2 | 7019 |
| PCSK5 | 6597 |
| APOB | 6172 |
| ALB | 5965 |
| CETP | 5470 |
| APOA4 | 444 |
Metabolism of steroids
| 632 | |
|---|---|
| set | Metabolism of steroids |
| setSize | 130 |
| pANOVA | 0.00024 |
| s.dist | 0.187 |
| p.adjustANOVA | 0.00973 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SEC24D | 14520 |
| MSMO1 | 14517 |
| AKR1C2 | 14496 |
| AKR1C1 | 14484 |
| HMGCS1 | 14473 |
| SQLE | 14468 |
| IDI1 | 14452 |
| HMGCR | 14408 |
| MVK | 14363 |
| DHCR7 | 14319 |
| SREBF2 | 14223 |
| MVD | 14220 |
| FDFT1 | 14189 |
| LSS | 14165 |
| ELOVL6 | 14093 |
| SEC24A | 14088 |
| SLC51B | 14011 |
| NCOA6 | 13941 |
| PPARA | 13906 |
| OSBP | 13854 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SEC24D | 14520 |
| MSMO1 | 14517 |
| AKR1C2 | 14496 |
| AKR1C1 | 14484 |
| HMGCS1 | 14473 |
| SQLE | 14468 |
| IDI1 | 14452 |
| HMGCR | 14408 |
| MVK | 14363 |
| DHCR7 | 14319 |
| SREBF2 | 14223 |
| MVD | 14220 |
| FDFT1 | 14189 |
| LSS | 14165 |
| ELOVL6 | 14093 |
| SEC24A | 14088 |
| SLC51B | 14011 |
| NCOA6 | 13941 |
| PPARA | 13906 |
| OSBP | 13854 |
| OSBPL2 | 13812 |
| AMACR | 13555 |
| RAN | 13497 |
| SCD | 13413 |
| GPAM | 13366 |
| ACAT2 | 13351 |
| KPNB1 | 13324 |
| ARV1 | 13201 |
| SEC24C | 13047 |
| AKR1B1 | 13033 |
| FDPS | 12999 |
| CYP51A1 | 12901 |
| HSD17B11 | 12833 |
| TM7SF2 | 12785 |
| NR1H4 | 12674 |
| MBTPS1 | 12523 |
| SCP2 | 12518 |
| INSIG2 | 12407 |
| CYP19A1 | 12287 |
| AKR1B15 | 12286 |
| CYP27B1 | 12039 |
| SCAP | 11960 |
| HSD17B12 | 11955 |
| ABCC3 | 11944 |
| NSDHL | 11890 |
| SLC51A | 11608 |
| SEC24B | 11541 |
| ACACB | 11531 |
| MED1 | 11468 |
| SP1 | 11396 |
| DHCR24 | 11041 |
| CYP11A1 | 10772 |
| PIAS4 | 10596 |
| STARD5 | 10571 |
| ACOT8 | 10550 |
| GGPS1 | 10498 |
| SC5D | 10071 |
| NCOA1 | 9914 |
| STARD3 | 9872 |
| CHD9 | 9842 |
| CYP39A1 | 9791 |
| EBP | 9739 |
| NFYB | 9634 |
| STAR | 9140 |
| OSBPL3 | 9104 |
| OSBPL9 | 9090 |
| HELZ2 | 9086 |
| NCOA2 | 9072 |
| STARD4 | 9071 |
| SRD5A3 | 9027 |
| PLPP6 | 8931 |
| RXRA | 8607 |
| MTF1 | 8354 |
| SLCO1B3 | 8303 |
| CYP21A2 | 8249 |
| HSD17B2 | 8238 |
| CREBBP | 8214 |
| CYP27A1 | 7994 |
| BAAT | 7606 |
| SREBF1 | 7517 |
| OSBPL7 | 7117 |
| MBTPS2 | 7019 |
| AKR1C4 | 6744 |
| CARM1 | 6725 |
| CYP2R1 | 6680 |
| LBR | 6666 |
| PMVK | 6407 |
| SAR1B | 6198 |
| ALB | 5965 |
| FDXR | 5910 |
| SEC23A | 5659 |
| HSD3B7 | 5445 |
| NFYA | 5142 |
| GC | 5084 |
| HSD17B7 | 5017 |
| FDX1 | 4743 |
| HSD17B1 | 4656 |
| CYP24A1 | 4653 |
| SMARCD3 | 4455 |
| AKR1D1 | 4223 |
| TGS1 | 4181 |
| SLCO1A2 | 4048 |
| HSD17B4 | 3810 |
| SERPINA6 | 3759 |
| FASN | 3698 |
| TBL1X | 3308 |
| SRD5A1 | 3243 |
| CYP7A1 | 3133 |
| SUMO2 | 3089 |
| SLC27A5 | 3043 |
| OSBPL6 | 2900 |
| PTGIS | 2883 |
| TBL1XR1 | 2795 |
| UBE2I | 2653 |
| OSBPL1A | 2101 |
| LGMN | 1966 |
| STARD3NL | 1953 |
| ACOX2 | 1774 |
| CUBN | 1678 |
| SLC27A2 | 1635 |
| NFYC | 1395 |
| HSD11B2 | 1264 |
| HSD17B14 | 944 |
| CYP8B1 | 789 |
| CYP17A1 | 777 |
| FDX2 | 557 |
| CYP46A1 | 347 |
| ACACA | 236 |
| TSPO | 220 |
| AKR1C3 | 54 |
Platelet activation, signaling and aggregation
| 802 | |
|---|---|
| set | Platelet activation, signaling and aggregation |
| setSize | 189 |
| pANOVA | 0.000251 |
| s.dist | 0.155 |
| p.adjustANOVA | 0.00989 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MANF | 14533 |
| SERPING1 | 14532 |
| HSPA5 | 14531 |
| KNG1 | 14503 |
| PLG | 14495 |
| IGF2 | 14477 |
| ARRB1 | 14420 |
| FGA | 14346 |
| SERPINA3 | 14304 |
| LAMP2 | 14291 |
| TGFB1 | 14241 |
| BCAR1 | 14233 |
| SHC1 | 14209 |
| PCYOX1L | 14197 |
| DAGLA | 14113 |
| FLNA | 14081 |
| FGB | 14018 |
| ITIH3 | 13927 |
| ACTN1 | 13824 |
| LHFPL2 | 13786 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MANF | 14533 |
| SERPING1 | 14532 |
| HSPA5 | 14531 |
| KNG1 | 14503 |
| PLG | 14495 |
| IGF2 | 14477 |
| ARRB1 | 14420 |
| FGA | 14346 |
| SERPINA3 | 14304 |
| LAMP2 | 14291 |
| TGFB1 | 14241 |
| BCAR1 | 14233 |
| SHC1 | 14209 |
| PCYOX1L | 14197 |
| DAGLA | 14113 |
| FLNA | 14081 |
| FGB | 14018 |
| ITIH3 | 13927 |
| ACTN1 | 13824 |
| LHFPL2 | 13786 |
| GNA13 | 13689 |
| PRKCZ | 13676 |
| VEGFB | 13646 |
| A1BG | 13591 |
| BRPF3 | 13542 |
| APP | 13532 |
| ANXA5 | 13476 |
| ALDOA | 13474 |
| APOA1 | 13433 |
| ADRA2C | 13422 |
| SERPINF2 | 13388 |
| TOR4A | 13305 |
| PDGFB | 13263 |
| ABHD12 | 13159 |
| TIMP1 | 13158 |
| PFN1 | 13146 |
| GNA12 | 13131 |
| LCK | 13069 |
| DGKZ | 12992 |
| GNG10 | 12977 |
| SERPINA4 | 12966 |
| HABP4 | 12946 |
| TAGLN2 | 12885 |
| TLN1 | 12872 |
| FGG | 12809 |
| CD63 | 12800 |
| ITPR3 | 12768 |
| ABCC4 | 12699 |
| MAPK3 | 12684 |
| THPO | 12650 |
| DGKE | 12576 |
| PTPN6 | 12513 |
| GNA11 | 12425 |
| FAM3C | 12377 |
| NHLRC2 | 12356 |
| ITIH4 | 12212 |
| WDR1 | 12167 |
| CFL1 | 12075 |
| CYB5R1 | 11951 |
| CRK | 11901 |
| PRKCD | 11872 |
| GNG4 | 11731 |
| RAF1 | 11708 |
| PRKCE | 11606 |
| RHOB | 11537 |
| PROS1 | 11519 |
| THBS1 | 11408 |
| SERPINE1 | 11217 |
| RHOA | 11182 |
| TF | 11111 |
| PSAP | 11023 |
| SOD1 | 10975 |
| APOH | 10937 |
| DGKA | 10844 |
| LEFTY2 | 10803 |
| AAMP | 10725 |
| CLU | 10723 |
| MAPK1 | 10705 |
| CD109 | 10579 |
| CFD | 10570 |
| TMX3 | 10142 |
| TMSB4X | 10078 |
| DGKK | 9983 |
| CD36 | 9953 |
| VAV3 | 9861 |
| ACTN4 | 9828 |
| GNAI3 | 9793 |
| CALU | 9602 |
| GNB2 | 9583 |
| VEGFA | 9433 |
| HRG | 9408 |
| PPIA | 9393 |
| APOOL | 9286 |
| PIK3R1 | 9259 |
| PTK2 | 9198 |
| ITPR1 | 9146 |
| CSK | 8692 |
| CAP1 | 8634 |
| DAGLB | 8497 |
| ORM1 | 8400 |
| GNG7 | 8395 |
| VCL | 8357 |
| GNAI2 | 8246 |
| ENDOD1 | 8089 |
| TEX264 | 7996 |
| PLCG2 | 7942 |
| GNG5 | 7830 |
| LAT | 7813 |
| GTPBP2 | 7790 |
| CD9 | 7746 |
| SERPINA1 | 7622 |
| FERMT3 | 7573 |
| SRC | 7516 |
| STXBP3 | 7400 |
| F2R | 7320 |
| APLP2 | 7009 |
| LGALS3BP | 6917 |
| PTPN1 | 6909 |
| RAP1B | 6830 |
| ARRB2 | 6824 |
| GNB1 | 6796 |
| FN1 | 6525 |
| GRB2 | 6346 |
| LYN | 6328 |
| TIMP3 | 6229 |
| AKT1 | 6160 |
| ALB | 5965 |
| ECM1 | 5858 |
| PIK3CA | 5849 |
| RHOG | 5747 |
| CHID1 | 5583 |
| PDGFA | 5524 |
| VAV2 | 5425 |
| PIK3CB | 5379 |
| DGKD | 5302 |
| GAS6 | 5226 |
| F2RL3 | 5187 |
| GNAI1 | 5167 |
| PIK3R3 | 4734 |
| PRKCA | 4709 |
| SCCPDH | 4529 |
| CDC42 | 4489 |
| MAPK14 | 4391 |
| ITPR2 | 4366 |
| DGKQ | 4067 |
| FYN | 3783 |
| GNB4 | 3781 |
| VWF | 3777 |
| DGKG | 3322 |
| PRKCH | 3185 |
| SPARC | 3167 |
| SPP2 | 3138 |
| CDC37L1 | 3066 |
| SELENOP | 2773 |
| PIK3R2 | 2728 |
| QSOX1 | 2518 |
| ORM2 | 2502 |
| SYTL4 | 2386 |
| A2M | 2340 |
| TBXA2R | 2235 |
| PECAM1 | 2152 |
| GNB3 | 2063 |
| SOS1 | 1928 |
| ABHD6 | 1891 |
| RARRES2 | 1845 |
| YWHAZ | 1810 |
| PTPN11 | 1770 |
| F5 | 1638 |
| VTI1B | 1619 |
| GNAQ | 1588 |
| DGKH | 1586 |
| OLA1 | 1578 |
| STXBP2 | 1474 |
| F8 | 1460 |
| ITGA2B | 1391 |
| GNB5 | 1388 |
| CALM1 | 1340 |
| TUBA4A | 1335 |
| F2 | 1246 |
| STX4 | 995 |
| RAPGEF4 | 863 |
| PDPK1 | 782 |
| FCER1G | 746 |
| MAGED2 | 745 |
| TGFB3 | 649 |
| RAP1A | 604 |
| PHACTR2 | 144 |
| RAC1 | 95 |
| AHSG | 62 |
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
| 99 | |
|---|---|
| set | Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| setSize | 64 |
| pANOVA | 0.000304 |
| s.dist | 0.261 |
| p.adjustANOVA | 0.0116 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SLC17A5 | 14434 |
| GFPT1 | 14406 |
| MVD | 14220 |
| NANS | 14204 |
| GMPPB | 14096 |
| ST3GAL4 | 14033 |
| NEU1 | 13953 |
| ST6GALNAC4 | 13912 |
| SLC35C1 | 13821 |
| ALG3 | 13700 |
| NEU3 | 13653 |
| ALG2 | 13631 |
| ALG5 | 13488 |
| NUS1 | 13362 |
| NEU4 | 13335 |
| GMPPA | 13267 |
| CTSA | 13149 |
| ALG12 | 12752 |
| DPAGT1 | 12688 |
| ALG11 | 12520 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SLC17A5 | 14434 |
| GFPT1 | 14406 |
| MVD | 14220 |
| NANS | 14204 |
| GMPPB | 14096 |
| ST3GAL4 | 14033 |
| NEU1 | 13953 |
| ST6GALNAC4 | 13912 |
| SLC35C1 | 13821 |
| ALG3 | 13700 |
| NEU3 | 13653 |
| ALG2 | 13631 |
| ALG5 | 13488 |
| NUS1 | 13362 |
| NEU4 | 13335 |
| GMPPA | 13267 |
| CTSA | 13149 |
| ALG12 | 12752 |
| DPAGT1 | 12688 |
| ALG11 | 12520 |
| ST3GAL1 | 12408 |
| RENBP | 12130 |
| GNE | 11517 |
| PGM3 | 11367 |
| ST3GAL3 | 11257 |
| ALG10B | 11213 |
| PMM2 | 10956 |
| CMAS | 10871 |
| FPGT | 10685 |
| DOLPP1 | 10517 |
| AMDHD2 | 10267 |
| ST6GALNAC6 | 10212 |
| ST3GAL5 | 9630 |
| RFT1 | 9608 |
| MPI | 9596 |
| ST3GAL2 | 9594 |
| ALG6 | 9374 |
| ALG1 | 9207 |
| SRD5A3 | 9027 |
| NUDT14 | 8814 |
| NAGK | 8559 |
| SLC35A1 | 7418 |
| MPDU1 | 7080 |
| GMDS | 7053 |
| ST3GAL6 | 6829 |
| ALG14 | 6723 |
| DPM3 | 6189 |
| PMM1 | 5521 |
| ALG10 | 5133 |
| FUOM | 4976 |
| DHDDS | 4636 |
| GNPNAT1 | 4628 |
| ST8SIA1 | 4428 |
| DPM2 | 4373 |
| ST6GAL1 | 3739 |
| ST8SIA5 | 3583 |
| GLB1 | 3064 |
| ALG13 | 2687 |
| DPM1 | 2494 |
| ALG8 | 2188 |
| UAP1 | 1828 |
| NANP | 957 |
| ALG9 | 865 |
| DOLK | 213 |
Metabolism of proteins
| 630 | |
|---|---|
| set | Metabolism of proteins |
| setSize | 1550 |
| pANOVA | 0.00034 |
| s.dist | 0.0556 |
| p.adjustANOVA | 0.0126 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CALR | 14529 |
| RAB17 | 14521 |
| SEC24D | 14520 |
| DNAJC3 | 14516 |
| HSP90B1 | 14514 |
| SEL1L | 14508 |
| KNG1 | 14503 |
| PCSK9 | 14502 |
| SELENOS | 14498 |
| PLG | 14495 |
| MUC5B | 14487 |
| SYVN1 | 14485 |
| PDIA6 | 14482 |
| EDEM1 | 14479 |
| IGF2 | 14477 |
| SOCS3 | 14476 |
| WFS1 | 14466 |
| KLF4 | 14463 |
| CANX | 14462 |
| PDIA3 | 14454 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CALR | 14529 |
| RAB17 | 14521 |
| SEC24D | 14520 |
| DNAJC3 | 14516 |
| HSP90B1 | 14514 |
| SEL1L | 14508 |
| KNG1 | 14503 |
| PCSK9 | 14502 |
| SELENOS | 14498 |
| PLG | 14495 |
| MUC5B | 14487 |
| SYVN1 | 14485 |
| PDIA6 | 14482 |
| EDEM1 | 14479 |
| IGF2 | 14477 |
| SOCS3 | 14476 |
| WFS1 | 14466 |
| KLF4 | 14463 |
| CANX | 14462 |
| PDIA3 | 14454 |
| ERO1B | 14442 |
| SLC17A5 | 14434 |
| TMED2 | 14433 |
| KLHL21 | 14429 |
| MCFD2 | 14425 |
| ARRB1 | 14420 |
| C3 | 14417 |
| GCNT3 | 14407 |
| GFPT1 | 14406 |
| MIA3 | 14404 |
| DERL2 | 14399 |
| MAGT1 | 14398 |
| C4A | 14381 |
| SEC61A1 | 14374 |
| WSB2 | 14373 |
| ARSG | 14366 |
| RPN1 | 14350 |
| FGA | 14346 |
| SSR4 | 14338 |
| FUT3 | 14335 |
| TRAM1 | 14331 |
| EIF4A1 | 14329 |
| SEC11C | 14325 |
| OS9 | 14320 |
| FAM20A | 14315 |
| RPL36AL | 14313 |
| CP | 14292 |
| EIF3A | 14290 |
| ASB2 | 14280 |
| SEC61B | 14278 |
| UGGT1 | 14270 |
| ETF1 | 14268 |
| ODAM | 14256 |
| ARSB | 14246 |
| TGFB1 | 14241 |
| TMED7 | 14240 |
| SSR3 | 14235 |
| MVD | 14220 |
| MATN3 | 14207 |
| SSR1 | 14205 |
| NANS | 14204 |
| MELTF | 14199 |
| MLEC | 14193 |
| SRPRB | 14181 |
| P4HB | 14170 |
| BMP4 | 14148 |
| VGF | 14140 |
| UBE2L6 | 14134 |
| FBXL16 | 14129 |
| GMPPB | 14096 |
| SEC24A | 14088 |
| GSPT1 | 14070 |
| TRAPPC6A | 14069 |
| SLC30A7 | 14058 |
| SEC13 | 14049 |
| ST3GAL4 | 14033 |
| CDK1 | 14027 |
| STT3A | 14026 |
| CBX5 | 14012 |
| POMT2 | 14007 |
| SPCS3 | 13996 |
| ANK2 | 13993 |
| TMEM115 | 13976 |
| SSR2 | 13968 |
| NEU1 | 13953 |
| MBD6 | 13936 |
| ST6GALNAC4 | 13912 |
| PPARA | 13906 |
| VCP | 13902 |
| CSF1 | 13888 |
| RAB43 | 13874 |
| FURIN | 13851 |
| DPP4 | 13845 |
| HSPG2 | 13832 |
| GBA | 13831 |
| SLC35C1 | 13821 |
| SIAH2 | 13819 |
| DDX5 | 13814 |
| FBN1 | 13813 |
| PSMF1 | 13810 |
| N6AMT1 | 13806 |
| RAD23A | 13802 |
| UBE2C | 13793 |
| LGALS1 | 13778 |
| RECK | 13774 |
| GALNT11 | 13771 |
| PARS2 | 13767 |
| SOCS5 | 13766 |
| KIF5A | 13752 |
| RNF5 | 13745 |
| UIMC1 | 13741 |
| FKBP9 | 13730 |
| RAB20 | 13727 |
| TTLL3 | 13715 |
| NUP37 | 13706 |
| ALG3 | 13700 |
| SERPINC1 | 13683 |
| TUBA1B | 13681 |
| TRAPPC10 | 13677 |
| AGT | 13674 |
| MRPS25 | 13672 |
| FOXK2 | 13656 |
| NEU3 | 13653 |
| LMAN2 | 13641 |
| ALG2 | 13631 |
| USP16 | 13615 |
| FUCA2 | 13600 |
| COPB2 | 13594 |
| RAB22A | 13585 |
| CD55 | 13575 |
| PPP6R1 | 13558 |
| ARCN1 | 13549 |
| TMED9 | 13545 |
| ADAMTSL4 | 13538 |
| APP | 13532 |
| VHL | 13531 |
| KEAP1 | 13510 |
| CES1 | 13506 |
| TOP1 | 13490 |
| ALG5 | 13488 |
| EP300 | 13485 |
| CLSPN | 13484 |
| MAN1A2 | 13466 |
| PSME4 | 13450 |
| APOA1 | 13433 |
| NFKBIA | 13427 |
| RAB37 | 13426 |
| PSMD2 | 13423 |
| ADRA2C | 13422 |
| MRPL24 | 13414 |
| DDOST | 13410 |
| DERL1 | 13398 |
| SRP68 | 13394 |
| ADAMTS10 | 13383 |
| SPON2 | 13375 |
| MGAT1 | 13371 |
| MTRF1L | 13369 |
| NUS1 | 13362 |
| CBX2 | 13350 |
| DNMT3B | 13348 |
| NEU4 | 13335 |
| ADAMTS2 | 13309 |
| GATA4 | 13306 |
| SRP19 | 13297 |
| RNF185 | 13291 |
| THSD4 | 13286 |
| POM121 | 13281 |
| GMPPA | 13267 |
| CHST10 | 13262 |
| APOA2 | 13191 |
| AURKB | 13190 |
| TOP2A | 13176 |
| TIMP1 | 13158 |
| CTSA | 13149 |
| MGAT4B | 13132 |
| B4GALT5 | 13121 |
| RARA | 13109 |
| CCT5 | 13070 |
| DAD1 | 13053 |
| KIFC3 | 13049 |
| SEC24C | 13047 |
| TTLL11 | 13041 |
| UBE2J2 | 13040 |
| STC2 | 13029 |
| NUP210 | 13025 |
| KBTBD6 | 13016 |
| TECTB | 13015 |
| NOTUM | 12998 |
| TBC1D20 | 12985 |
| GNG10 | 12977 |
| CUL9 | 12968 |
| KBTBD7 | 12967 |
| RPN2 | 12964 |
| HLTF | 12961 |
| PIGG | 12950 |
| SAFB | 12947 |
| TUBA1C | 12940 |
| TUBB4B | 12934 |
| DDB2 | 12925 |
| COG8 | 12910 |
| SEC16B | 12908 |
| DPH5 | 12882 |
| SMAD3 | 12871 |
| TTLL1 | 12868 |
| PROC | 12863 |
| DCAF11 | 12860 |
| YOD1 | 12859 |
| GGA2 | 12852 |
| RNF103 | 12848 |
| LONP2 | 12828 |
| TMED10 | 12817 |
| FGG | 12809 |
| SERPIND1 | 12796 |
| TAB1 | 12789 |
| ART4 | 12770 |
| NSMCE1 | 12769 |
| ALG12 | 12752 |
| CYLD | 12727 |
| SCMH1 | 12722 |
| EIF5 | 12721 |
| HCFC1 | 12714 |
| CDCA8 | 12700 |
| IFIH1 | 12693 |
| RWDD3 | 12691 |
| DPAGT1 | 12688 |
| POM121C | 12687 |
| NR1H4 | 12674 |
| ARF1 | 12642 |
| RAB9A | 12633 |
| JOSD1 | 12588 |
| CCNA2 | 12587 |
| GALNT2 | 12555 |
| SEC16A | 12546 |
| WAC | 12537 |
| COPE | 12527 |
| MBTPS1 | 12523 |
| ALG11 | 12520 |
| PSMD6 | 12502 |
| COG3 | 12497 |
| IKBKG | 12493 |
| FBXW5 | 12489 |
| OTUD5 | 12487 |
| SRP14 | 12470 |
| PRKCSH | 12463 |
| SPCS2 | 12458 |
| PCNA | 12452 |
| CCT2 | 12444 |
| NAPA | 12433 |
| GNA11 | 12425 |
| ST3GAL1 | 12408 |
| ADAMTS6 | 12405 |
| EIF4G1 | 12400 |
| EIF4B | 12396 |
| ZRANB1 | 12391 |
| KDELR2 | 12387 |
| MUL1 | 12386 |
| UBE2F | 12374 |
| SIN3A | 12373 |
| PCGF2 | 12369 |
| RORA | 12360 |
| SPP1 | 12355 |
| PPARGC1A | 12350 |
| CCT6A | 12336 |
| MGAT5 | 12324 |
| ENGASE | 12309 |
| OGT | 12301 |
| ASXL2 | 12292 |
| FN3KRP | 12265 |
| DCUN1D3 | 12244 |
| ARF4 | 12225 |
| RAB7A | 12220 |
| ADAMTS9 | 12207 |
| PSMA2 | 12203 |
| ASB13 | 12175 |
| RIPK2 | 12158 |
| SEC31A | 12138 |
| UBE2G1 | 12134 |
| IGFBP2 | 12133 |
| RENBP | 12130 |
| AXIN2 | 12097 |
| USP30 | 12091 |
| VNN3 | 12074 |
| F7 | 12069 |
| PSMA1 | 12052 |
| CSNK1D | 12038 |
| EXOC1 | 12013 |
| PCMT1 | 11983 |
| HIPK2 | 11978 |
| DDB1 | 11967 |
| MRPS6 | 11965 |
| EIF5A | 11952 |
| VCAN | 11899 |
| FKBP8 | 11886 |
| DDA1 | 11862 |
| DPH2 | 11858 |
| PIGK | 11827 |
| PROZ | 11823 |
| CCT8 | 11813 |
| CCP110 | 11807 |
| MRPS31 | 11782 |
| RAD52 | 11769 |
| SUMF1 | 11754 |
| APH1B | 11741 |
| GNG4 | 11731 |
| PSMC1 | 11724 |
| SHPRH | 11706 |
| COPG2 | 11691 |
| BARD1 | 11687 |
| FBXO41 | 11685 |
| SENP8 | 11684 |
| LARS2 | 11681 |
| NR5A2 | 11680 |
| MRPL2 | 11658 |
| PSMD3 | 11655 |
| ARSI | 11653 |
| SRP72 | 11640 |
| EDEM2 | 11628 |
| TAF9B | 11625 |
| CDC34 | 11619 |
| BACE1 | 11590 |
| TRIM25 | 11574 |
| FBXO31 | 11563 |
| NUP107 | 11561 |
| PSME2 | 11555 |
| SEC24B | 11541 |
| IGFBP3 | 11532 |
| SOCS6 | 11523 |
| USP13 | 11521 |
| PROS1 | 11519 |
| GNE | 11517 |
| RAD18 | 11508 |
| DYNLL2 | 11507 |
| XPNPEP2 | 11506 |
| FBXW4 | 11502 |
| RNF40 | 11493 |
| UBXN1 | 11466 |
| CISH | 11440 |
| USP2 | 11427 |
| BLM | 11423 |
| KIF5B | 11419 |
| B3GLCT | 11411 |
| DCAF10 | 11410 |
| THBS1 | 11408 |
| FBXO17 | 11405 |
| PTRH2 | 11393 |
| RAB5A | 11392 |
| NUP35 | 11387 |
| DPH1 | 11373 |
| PSMD14 | 11371 |
| PGM3 | 11367 |
| MRPL30 | 11343 |
| HRC | 11335 |
| CDC25A | 11334 |
| PGAP1 | 11332 |
| RAB2A | 11326 |
| SKP2 | 11323 |
| MRPS15 | 11322 |
| VASH2 | 11320 |
| MRPL17 | 11317 |
| PNPLA2 | 11306 |
| PSMD1 | 11280 |
| ST3GAL3 | 11257 |
| CPE | 11255 |
| OTUB2 | 11254 |
| TFG | 11250 |
| THSD1 | 11244 |
| ALG10B | 11213 |
| GOLGA2 | 11209 |
| STX5 | 11191 |
| FBXO32 | 11189 |
| RHOA | 11182 |
| MRPS16 | 11175 |
| PUM2 | 11167 |
| RAB32 | 11166 |
| MRPL16 | 11164 |
| USP18 | 11159 |
| STAMBP | 11154 |
| EIF3I | 11151 |
| PIGW | 11146 |
| NUP205 | 11144 |
| MRPL1 | 11138 |
| RAB35 | 11131 |
| MSRB2 | 11130 |
| USP22 | 11124 |
| IGFALS | 11119 |
| TF | 11111 |
| PIGL | 11096 |
| RPL19 | 11094 |
| SMURF2 | 11093 |
| FSTL3 | 11092 |
| TPGS1 | 11091 |
| RNF20 | 11085 |
| ASB6 | 11077 |
| PPP6C | 11074 |
| NUP93 | 11067 |
| MRPL38 | 11062 |
| MRPL55 | 11058 |
| UCHL3 | 11055 |
| AGTPBP1 | 11045 |
| CETN2 | 11018 |
| YY1 | 11015 |
| UCN | 11013 |
| RABGGTB | 10986 |
| HLA-A | 10971 |
| EIF2S1 | 10961 |
| PMM2 | 10956 |
| TADA2B | 10948 |
| SENP5 | 10920 |
| AARS2 | 10908 |
| ACTR1A | 10903 |
| COPS2 | 10902 |
| NAE1 | 10901 |
| F10 | 10888 |
| CMAS | 10871 |
| MRPS2 | 10865 |
| ARL2 | 10857 |
| RPS7 | 10850 |
| UBE2T | 10846 |
| PRMT3 | 10843 |
| COPG1 | 10840 |
| FUT8 | 10839 |
| EIF3B | 10829 |
| HARS2 | 10804 |
| EEF1D | 10800 |
| USP42 | 10780 |
| FBXL5 | 10775 |
| COMMD6 | 10773 |
| NUCB1 | 10770 |
| AURKAIP1 | 10765 |
| KDELR1 | 10752 |
| NR1I2 | 10746 |
| VAMP2 | 10744 |
| CTSH | 10743 |
| PTP4A2 | 10739 |
| COPS7A | 10738 |
| MRPS12 | 10736 |
| CDC20 | 10732 |
| DPH3 | 10720 |
| UBA52 | 10707 |
| FPGT | 10685 |
| ACTB | 10683 |
| LARGE1 | 10682 |
| EIF4H | 10679 |
| MRPL3 | 10675 |
| TPGS2 | 10668 |
| NOP58 | 10662 |
| EEF2 | 10659 |
| SRP9 | 10650 |
| VCPIP1 | 10640 |
| CSNK2A1 | 10637 |
| EIF4A2 | 10631 |
| RPL11 | 10624 |
| RPL10 | 10608 |
| PIAS4 | 10596 |
| ACTR10 | 10590 |
| RAB40C | 10588 |
| MGAT4A | 10584 |
| CD109 | 10579 |
| DCAF7 | 10568 |
| RPS15 | 10567 |
| RPA1 | 10563 |
| MFGE8 | 10560 |
| VNN1 | 10554 |
| PIGZ | 10536 |
| KIF13A | 10525 |
| NUP188 | 10521 |
| FAU | 10520 |
| DOLPP1 | 10517 |
| GBF1 | 10507 |
| RPL14 | 10500 |
| MRPL47 | 10494 |
| DPH6 | 10486 |
| BPIFB2 | 10473 |
| PSMB9 | 10430 |
| ATXN7 | 10416 |
| EIF5A2 | 10412 |
| COMMD5 | 10389 |
| EPAS1 | 10387 |
| SPTBN1 | 10356 |
| YKT6 | 10349 |
| NOD1 | 10348 |
| COPS8 | 10337 |
| PSMB6 | 10326 |
| WSB1 | 10308 |
| PSMC6 | 10307 |
| RAB31 | 10305 |
| KLHL42 | 10303 |
| CHM | 10293 |
| MRPL14 | 10287 |
| SNX3 | 10279 |
| DCAF4 | 10278 |
| CAPZA1 | 10272 |
| AMDHD2 | 10267 |
| B4GALT3 | 10265 |
| AREG | 10258 |
| NSF | 10249 |
| EIF2B5 | 10248 |
| EEF1B2 | 10243 |
| TRIM27 | 10241 |
| ST6GALNAC6 | 10212 |
| ARFGAP3 | 10209 |
| RNF181 | 10206 |
| EIF2B2 | 10200 |
| PSMC4 | 10196 |
| SRPRA | 10175 |
| MRPL23 | 10172 |
| UBE2H | 10168 |
| KAT2B | 10158 |
| TNKS | 10153 |
| COL7A1 | 10152 |
| TGFBI | 10140 |
| GOLM1 | 10136 |
| RPS5 | 10135 |
| NUP88 | 10134 |
| CCDC59 | 10132 |
| H2AFX | 10131 |
| XPC | 10123 |
| FEM1C | 10115 |
| GALNT10 | 10114 |
| DCAF16 | 10105 |
| MRPL42 | 10095 |
| ADORA2A | 10081 |
| RUVBL1 | 10058 |
| SPSB3 | 10054 |
| TCP1 | 10050 |
| NUP50 | 10047 |
| EIF3G | 10029 |
| PTEN | 10023 |
| INCENP | 10005 |
| EVA1A | 9995 |
| RPS11 | 9977 |
| FBXO44 | 9964 |
| CASP8AP2 | 9946 |
| CUL4B | 9945 |
| CDC73 | 9943 |
| RNF123 | 9939 |
| NR5A1 | 9936 |
| MMP2 | 9932 |
| RABGGTA | 9926 |
| NCOA1 | 9914 |
| PIGM | 9913 |
| RPS19 | 9909 |
| SP3 | 9908 |
| ANK1 | 9901 |
| HSPA8 | 9895 |
| RPS28 | 9891 |
| METTL21A | 9883 |
| USP14 | 9882 |
| KDM1B | 9876 |
| PSMD9 | 9853 |
| EIF2B3 | 9835 |
| TSPAN14 | 9825 |
| COPS3 | 9810 |
| AGBL2 | 9809 |
| COMMD7 | 9798 |
| MRPL34 | 9796 |
| DCUN1D2 | 9784 |
| BIRC5 | 9771 |
| MRPL41 | 9760 |
| TTF1 | 9758 |
| ASB9 | 9735 |
| RBBP7 | 9712 |
| TRAPPC2L | 9709 |
| ADORA2B | 9698 |
| PFDN6 | 9689 |
| MRPL35 | 9685 |
| PSMD5 | 9676 |
| GPLD1 | 9667 |
| STAM | 9665 |
| BRCA1 | 9663 |
| DCAF5 | 9642 |
| CSNK2A2 | 9641 |
| ST3GAL5 | 9630 |
| EIF3J | 9629 |
| MRPL32 | 9619 |
| ARSD | 9613 |
| RARS2 | 9611 |
| KLHL22 | 9610 |
| RFT1 | 9608 |
| CALU | 9602 |
| KAT2A | 9597 |
| MPI | 9596 |
| ST3GAL2 | 9594 |
| GNB2 | 9583 |
| TGFA | 9574 |
| IGFBP4 | 9571 |
| INHBE | 9570 |
| ADAMTS13 | 9541 |
| NSMCE2 | 9534 |
| TRAPPC9 | 9528 |
| MRPS18C | 9522 |
| RTN4RL2 | 9479 |
| SEH1L | 9474 |
| BCL10 | 9472 |
| MRPL51 | 9463 |
| COMMD3 | 9446 |
| EIF2S2 | 9437 |
| FBXO21 | 9436 |
| SMAD1 | 9435 |
| MRPL46 | 9431 |
| CTSC | 9398 |
| MBD1 | 9395 |
| RAB36 | 9394 |
| USP34 | 9391 |
| TNIP1 | 9381 |
| FAM20C | 9378 |
| ALG6 | 9374 |
| STS | 9373 |
| PSMD7 | 9371 |
| GALNT6 | 9366 |
| PSMD10 | 9356 |
| NCOR2 | 9331 |
| TMEM129 | 9321 |
| SUMO3 | 9299 |
| RPLP1 | 9291 |
| APOL1 | 9284 |
| MRPS21 | 9271 |
| PSMB7 | 9253 |
| CBX8 | 9242 |
| RPS12 | 9239 |
| EIF3M | 9224 |
| EIF4EBP1 | 9212 |
| ALG1 | 9207 |
| SHISA5 | 9203 |
| USP15 | 9193 |
| NICN1 | 9177 |
| UBE2M | 9174 |
| MRPS24 | 9158 |
| MUC15 | 9153 |
| FOXK1 | 9151 |
| USP9X | 9136 |
| PIGF | 9133 |
| POLB | 9130 |
| FBXL4 | 9111 |
| NUP155 | 9102 |
| B3GNT9 | 9094 |
| COG7 | 9093 |
| MRPL43 | 9092 |
| TP53BP1 | 9089 |
| RPL27A | 9081 |
| NCOA2 | 9072 |
| RPLP0 | 9067 |
| PHC1 | 9053 |
| PIGA | 9048 |
| FBXO22 | 9038 |
| SRD5A3 | 9027 |
| UBB | 9013 |
| DOHH | 9002 |
| ARF5 | 8998 |
| COG2 | 8997 |
| PEX12 | 8996 |
| RAB23 | 8961 |
| TRIM4 | 8937 |
| TUBA1A | 8932 |
| MRPS33 | 8930 |
| APEH | 8922 |
| AXIN1 | 8908 |
| PSMA4 | 8902 |
| ANPEP | 8901 |
| HGS | 8898 |
| NR1H3 | 8878 |
| RAB8B | 8875 |
| MRPL33 | 8854 |
| RAB40B | 8839 |
| BMI1 | 8838 |
| DCAF13 | 8826 |
| ASB1 | 8818 |
| DCAF8 | 8816 |
| NUDT14 | 8814 |
| HIF1A | 8807 |
| P2RY2 | 8802 |
| RPL35A | 8797 |
| B3GNT3 | 8781 |
| AFP | 8777 |
| PFDN1 | 8746 |
| EEF1A1 | 8740 |
| SKIV2L | 8733 |
| CUL1 | 8725 |
| COG1 | 8708 |
| DTL | 8690 |
| PEX2 | 8675 |
| PSMD4 | 8670 |
| COPB1 | 8664 |
| MRPL44 | 8651 |
| MSLN | 8649 |
| PSMC5 | 8646 |
| SMAD2 | 8639 |
| PIGQ | 8638 |
| RPL30 | 8630 |
| RXRA | 8607 |
| RAB11A | 8597 |
| MXRA8 | 8582 |
| CBX4 | 8580 |
| TMED3 | 8567 |
| SEC61G | 8561 |
| NAGK | 8559 |
| GALNT7 | 8555 |
| RNF144A | 8547 |
| IDE | 8543 |
| TRAPPC3 | 8524 |
| POMGNT2 | 8517 |
| RPS9 | 8515 |
| PLAUR | 8513 |
| NFRKB | 8510 |
| GGCX | 8504 |
| EEF1E1 | 8489 |
| LY6E | 8481 |
| NR3C1 | 8476 |
| TULP4 | 8471 |
| UBE2D3 | 8449 |
| HIF3A | 8437 |
| RAB42 | 8434 |
| GNG7 | 8395 |
| COG5 | 8389 |
| USP3 | 8383 |
| RPL18 | 8381 |
| COPA | 8376 |
| DCTN2 | 8375 |
| CSNK2B | 8368 |
| THRB | 8360 |
| FBXL20 | 8336 |
| RAE1 | 8335 |
| CKAP4 | 8327 |
| WDR20 | 8319 |
| CUL7 | 8310 |
| IGFBP1 | 8301 |
| TNFAIP3 | 8284 |
| TTR | 8283 |
| GADD45GIP1 | 8274 |
| POMT1 | 8266 |
| UBA2 | 8263 |
| MRPS22 | 8259 |
| EXOC3 | 8237 |
| DYNC1LI2 | 8235 |
| CPB2 | 8234 |
| CTR9 | 8230 |
| VCPKMT | 8222 |
| ASB7 | 8217 |
| CREBBP | 8214 |
| RPL26L1 | 8188 |
| NAPG | 8187 |
| TRMT112 | 8181 |
| RAB3A | 8176 |
| COMMD1 | 8164 |
| PSMD12 | 8163 |
| FBXO11 | 8152 |
| PIGB | 8147 |
| KLHL13 | 8137 |
| RPS29 | 8133 |
| RPL6 | 8132 |
| IGFBP7 | 8108 |
| MRPL12 | 8090 |
| STAT3 | 8078 |
| SLC30A6 | 8074 |
| ASB4 | 8067 |
| PSME3 | 8052 |
| TSPAN15 | 8046 |
| TSPAN33 | 7993 |
| SERPINA10 | 7992 |
| MANEA | 7987 |
| FBXW11 | 7986 |
| PIGV | 7983 |
| GGA3 | 7982 |
| GPC3 | 7971 |
| SLC30A5 | 7959 |
| TUBB2B | 7952 |
| FBXO4 | 7948 |
| NUP85 | 7946 |
| NUP98 | 7940 |
| ACTR5 | 7892 |
| EIF3D | 7889 |
| HERC2 | 7888 |
| ANKRD28 | 7882 |
| SENP2 | 7874 |
| RBX1 | 7850 |
| TOP2B | 7845 |
| GNG5 | 7830 |
| APOA5 | 7816 |
| B4GAT1 | 7803 |
| RHOT1 | 7793 |
| TTLL7 | 7789 |
| APOE | 7759 |
| EIF2S3 | 7757 |
| RAB15 | 7753 |
| NRN1L | 7736 |
| WARS2 | 7734 |
| MRPL11 | 7726 |
| TGFBR2 | 7714 |
| RING1 | 7710 |
| MRPL49 | 7704 |
| GAN | 7702 |
| PEX14 | 7694 |
| DCTN5 | 7690 |
| PFDN2 | 7675 |
| TUBB8 | 7651 |
| DYNC1H1 | 7639 |
| RAB24 | 7638 |
| EEF1G | 7628 |
| TXN | 7626 |
| SERPINA1 | 7622 |
| ZNF131 | 7607 |
| TBCA | 7588 |
| SORL1 | 7576 |
| TRRAP | 7571 |
| RNF168 | 7562 |
| MAN1B1 | 7534 |
| ADRM1 | 7511 |
| KCTD7 | 7510 |
| RPL28 | 7500 |
| PABPC1 | 7490 |
| FBXO6 | 7468 |
| COMMD9 | 7455 |
| INO80E | 7449 |
| RPSA | 7435 |
| SLC35A1 | 7418 |
| USO1 | 7413 |
| GPS1 | 7406 |
| NUB1 | 7395 |
| MYO5A | 7394 |
| GOLGB1 | 7386 |
| SPTBN2 | 7379 |
| USP12 | 7363 |
| RAB1B | 7340 |
| ADAMTSL2 | 7330 |
| RPL8 | 7307 |
| RPS4X | 7297 |
| RPS2 | 7293 |
| TUFM | 7286 |
| DCAF17 | 7273 |
| AP3M1 | 7269 |
| RPL29 | 7265 |
| RPL32 | 7263 |
| JOSD2 | 7257 |
| ETFBKMT | 7248 |
| LYZ | 7247 |
| USP37 | 7241 |
| RPL36 | 7221 |
| LMAN1 | 7220 |
| LMAN2L | 7218 |
| XRN2 | 7216 |
| LAMB1 | 7198 |
| RPL37 | 7194 |
| ADAMTS1 | 7179 |
| MAP3K7 | 7172 |
| INO80 | 7157 |
| UBE2A | 7140 |
| RPS17 | 7104 |
| UBE2E1 | 7102 |
| CST3 | 7101 |
| MRPL10 | 7100 |
| ITM2B | 7092 |
| RAB13 | 7089 |
| MPDU1 | 7080 |
| FBXW8 | 7078 |
| ATXN3 | 7075 |
| PHC2 | 7072 |
| KLHL9 | 7071 |
| RPS24 | 7060 |
| CDKN2A | 7056 |
| GMDS | 7053 |
| SIAH1 | 7045 |
| MRPS18B | 7044 |
| STAG1 | 7037 |
| GCNT4 | 7025 |
| APLP2 | 7009 |
| MGAT2 | 7002 |
| MDC1 | 6989 |
| DDX17 | 6985 |
| INO80D | 6967 |
| RAB1A | 6957 |
| RAB14 | 6952 |
| TBCD | 6931 |
| DAXX | 6929 |
| MRPS36 | 6924 |
| FBXO27 | 6911 |
| VBP1 | 6910 |
| KLHL2 | 6866 |
| RPS14 | 6851 |
| KIN | 6833 |
| ST3GAL6 | 6829 |
| ARRB2 | 6824 |
| B3GNT8 | 6820 |
| CD59 | 6818 |
| FBXO15 | 6797 |
| GNB1 | 6796 |
| TRAPPC2 | 6775 |
| GALNT3 | 6774 |
| KTN1 | 6769 |
| EXOC7 | 6748 |
| TNKS2 | 6742 |
| UBE2D1 | 6734 |
| ALG14 | 6723 |
| BET1L | 6669 |
| RPS27L | 6664 |
| BIRC3 | 6654 |
| DHPS | 6649 |
| PPARG | 6636 |
| UBD | 6630 |
| ACTR8 | 6616 |
| RANGAP1 | 6615 |
| RPS10 | 6612 |
| ZBED1 | 6594 |
| UBE2L3 | 6589 |
| SPHK1 | 6587 |
| SEM1 | 6566 |
| RAB5C | 6565 |
| RCN1 | 6562 |
| FN1 | 6525 |
| MBD5 | 6524 |
| TDG | 6520 |
| PIGP | 6509 |
| XRCC4 | 6479 |
| TRIM28 | 6471 |
| UBE2V2 | 6467 |
| DNMT3A | 6452 |
| LEO1 | 6444 |
| KLHL20 | 6424 |
| PSMA3 | 6422 |
| EIF5B | 6386 |
| RNF139 | 6382 |
| COPS6 | 6380 |
| SEC22A | 6374 |
| NUP54 | 6371 |
| SUMO1 | 6365 |
| CUL3 | 6363 |
| SEC11A | 6345 |
| COPS5 | 6317 |
| RPS15A | 6295 |
| CTNNB1 | 6288 |
| MRPL54 | 6283 |
| FARSB | 6282 |
| ELOB | 6272 |
| COG6 | 6266 |
| MRPL37 | 6255 |
| THRA | 6251 |
| MRPS26 | 6236 |
| EIF3E | 6234 |
| ASGR2 | 6225 |
| RPL7 | 6223 |
| GPR119 | 6222 |
| RAB33B | 6213 |
| FARSA | 6205 |
| RPL34 | 6203 |
| SAR1B | 6198 |
| DPM3 | 6189 |
| POMGNT1 | 6187 |
| APOB | 6172 |
| MRPL36 | 6159 |
| RAB4B | 6116 |
| C1GALT1C1 | 6112 |
| SATB2 | 6101 |
| PSMD8 | 6091 |
| MTFMT | 6084 |
| RPS21 | 6082 |
| RAD23B | 6054 |
| CCT3 | 6052 |
| NGLY1 | 6049 |
| BECN1 | 6036 |
| RPS16 | 6026 |
| SMAD7 | 6006 |
| RIPK1 | 6000 |
| FBXL22 | 5990 |
| RPS3 | 5985 |
| TPST2 | 5975 |
| RPL13A | 5970 |
| VDAC2 | 5966 |
| ALB | 5965 |
| TRAPPC1 | 5956 |
| RPLP2 | 5950 |
| LARGE2 | 5939 |
| STAM2 | 5933 |
| RPL35 | 5927 |
| MAN1C1 | 5920 |
| USP5 | 5894 |
| GFM1 | 5882 |
| USP8 | 5864 |
| ABCA3 | 5842 |
| WRN | 5841 |
| HNRNPK | 5839 |
| ASB3 | 5827 |
| TOMM70 | 5819 |
| RAB27A | 5804 |
| USP24 | 5792 |
| IGFBP6 | 5787 |
| PFDN5 | 5784 |
| DYNC1I2 | 5783 |
| RPS27A | 5776 |
| BAP1 | 5752 |
| TOPORS | 5743 |
| ICMT | 5741 |
| UHRF2 | 5740 |
| BABAM1 | 5721 |
| PARP1 | 5715 |
| AAAS | 5701 |
| PFDN4 | 5694 |
| ADAMTSL3 | 5688 |
| MRRF | 5669 |
| KBTBD8 | 5662 |
| SEC23A | 5659 |
| MRPL57 | 5658 |
| PSMA5 | 5657 |
| FBXL8 | 5631 |
| MRPS34 | 5623 |
| AMFR | 5612 |
| RAB5B | 5611 |
| EID3 | 5599 |
| RPL23A | 5592 |
| RPL10A | 5584 |
| RPS6 | 5569 |
| HDAC1 | 5563 |
| B4GALT6 | 5555 |
| ADAMTS7 | 5554 |
| ARSA | 5552 |
| ADAM10 | 5549 |
| RPL36A | 5542 |
| MRPS23 | 5535 |
| PMM1 | 5521 |
| RGS9 | 5517 |
| UBE2E3 | 5512 |
| RPS18 | 5504 |
| TTL | 5487 |
| RPL41 | 5472 |
| RELA | 5468 |
| VWA1 | 5457 |
| TGFBR1 | 5447 |
| STAG2 | 5443 |
| FBXL14 | 5439 |
| MRPL48 | 5438 |
| INO80B | 5426 |
| GANAB | 5417 |
| CTSD | 5416 |
| NUP43 | 5410 |
| USP21 | 5405 |
| HIC1 | 5389 |
| GALNT16 | 5384 |
| UBE2B | 5375 |
| TBCC | 5369 |
| CYR61 | 5367 |
| RPS13 | 5366 |
| PSMD13 | 5353 |
| GFM2 | 5337 |
| HLA-B | 5329 |
| USP11 | 5328 |
| FBXW7 | 5325 |
| RPL4 | 5324 |
| ACE2 | 5319 |
| MDM4 | 5318 |
| CCNE1 | 5315 |
| MRPL27 | 5301 |
| SMAD4 | 5290 |
| RAB26 | 5288 |
| FBXW10 | 5268 |
| B2M | 5242 |
| DYNC1LI1 | 5237 |
| TUBB1 | 5236 |
| NUP153 | 5230 |
| GAS6 | 5226 |
| FUCA1 | 5210 |
| RAB21 | 5208 |
| ANKRD9 | 5202 |
| PARK7 | 5199 |
| OTULIN | 5175 |
| PEX10 | 5162 |
| B4GALT2 | 5152 |
| ALG10 | 5133 |
| MRPS28 | 5120 |
| DCAF6 | 5119 |
| RPS23 | 5114 |
| UBE2Q2 | 5107 |
| SP100 | 5083 |
| RPL37A | 5072 |
| ADAMTS17 | 5058 |
| ARF3 | 5040 |
| RRAGA | 5038 |
| B3GALNT2 | 5034 |
| AGBL5 | 5032 |
| B4GALT4 | 5027 |
| USP19 | 5014 |
| MRPL39 | 5007 |
| STX17 | 4997 |
| ERCC8 | 4995 |
| TRAPPC6B | 4993 |
| EIF3L | 4991 |
| GPAA1 | 4990 |
| TARS2 | 4978 |
| DNAJC24 | 4977 |
| FUOM | 4976 |
| WDR5 | 4953 |
| PSMC2 | 4948 |
| SMC3 | 4924 |
| STX1A | 4922 |
| GGA1 | 4881 |
| B3GNT2 | 4879 |
| MRPL21 | 4873 |
| PSME1 | 4861 |
| THBS2 | 4856 |
| DYNLL1 | 4853 |
| OTUD3 | 4849 |
| EXOC6 | 4847 |
| CDH2 | 4845 |
| MAN2A2 | 4840 |
| PSENEN | 4828 |
| GATA6 | 4816 |
| INHBB | 4815 |
| DPH7 | 4778 |
| PRKDC | 4777 |
| POMK | 4768 |
| EIF4E | 4766 |
| CCDC8 | 4762 |
| DARS2 | 4756 |
| VASH1 | 4751 |
| SUDS3 | 4748 |
| RNF2 | 4732 |
| MOGS | 4728 |
| MRPS11 | 4718 |
| RPL39 | 4713 |
| GALNT4 | 4706 |
| UBA6 | 4704 |
| CUL4A | 4702 |
| SPCS1 | 4672 |
| RAB8A | 4658 |
| RPL18A | 4649 |
| USP48 | 4648 |
| PPA2 | 4640 |
| TECTA | 4639 |
| DHDDS | 4636 |
| GNPNAT1 | 4628 |
| RPL7A | 4625 |
| OBSL1 | 4622 |
| SPTAN1 | 4610 |
| MRPS27 | 4604 |
| NUP58 | 4603 |
| TMEM132A | 4597 |
| OXA1L | 4586 |
| EIF3K | 4569 |
| NEURL2 | 4562 |
| BRCC3 | 4560 |
| ERAL1 | 4546 |
| METTL22 | 4532 |
| DAG1 | 4498 |
| PIGO | 4481 |
| TSPAN5 | 4464 |
| RAB4A | 4453 |
| ST8SIA1 | 4428 |
| TPST1 | 4399 |
| RPS4Y1 | 4388 |
| KIF5C | 4382 |
| DPM2 | 4373 |
| FBXL19 | 4369 |
| TGOLN2 | 4352 |
| INHBC | 4351 |
| SMC5 | 4328 |
| CHGB | 4319 |
| STAMBPL1 | 4302 |
| FOXO4 | 4276 |
| RPL27 | 4268 |
| ZNF350 | 4246 |
| WRAP53 | 4218 |
| SMC6 | 4184 |
| NPM1 | 4183 |
| RPL22 | 4170 |
| FBXL3 | 4168 |
| MRPL22 | 4161 |
| DNMT1 | 4159 |
| PIGC | 4155 |
| CCNE2 | 4152 |
| RFWD2 | 4150 |
| TP53 | 4144 |
| NARS2 | 4126 |
| FGF23 | 4091 |
| CARS2 | 4056 |
| UBE2W | 4047 |
| SRP54 | 4041 |
| CNIH3 | 4025 |
| ETFB | 4002 |
| DCTN4 | 3979 |
| NUP214 | 3957 |
| MRPL4 | 3949 |
| SVBP | 3948 |
| PSMB3 | 3928 |
| TTLL4 | 3926 |
| RPL23 | 3923 |
| OTUD7B | 3920 |
| ASXL1 | 3914 |
| LTBP1 | 3905 |
| EDEM3 | 3904 |
| LRRC41 | 3889 |
| DCUN1D5 | 3884 |
| ASGR1 | 3870 |
| COG4 | 3852 |
| PIGH | 3848 |
| UBE2S | 3839 |
| MARS2 | 3819 |
| USP47 | 3795 |
| NAT8 | 3791 |
| GNB4 | 3781 |
| FBXO9 | 3776 |
| USP33 | 3761 |
| B3GNT4 | 3741 |
| ST6GAL1 | 3739 |
| VARS2 | 3738 |
| GORASP1 | 3727 |
| ZDHHC2 | 3717 |
| APC | 3716 |
| MYC | 3708 |
| TRIM13 | 3695 |
| RPL24 | 3686 |
| PSMB2 | 3678 |
| NEGR1 | 3667 |
| AGBL3 | 3660 |
| MSRB1 | 3659 |
| RPL38 | 3652 |
| RAB39B | 3618 |
| UBE2N | 3604 |
| IARS2 | 3601 |
| PAF1 | 3589 |
| ST8SIA5 | 3583 |
| RPS20 | 3578 |
| RTF1 | 3574 |
| HNRNPC | 3563 |
| RPL26 | 3560 |
| EEF1A1P5 | 3558 |
| MTA1 | 3553 |
| TBCB | 3552 |
| RAB3B | 3544 |
| MSRA | 3536 |
| SAE1 | 3527 |
| AIMP1 | 3508 |
| TRAPPC4 | 3487 |
| CCDC22 | 3481 |
| MRPS7 | 3479 |
| SEC22C | 3433 |
| CHML | 3428 |
| ITIH2 | 3417 |
| USP28 | 3404 |
| CAND1 | 3381 |
| MRPS30 | 3380 |
| MGAT4C | 3364 |
| MAT2B | 3339 |
| DCTN1 | 3338 |
| MAVS | 3323 |
| MRPL52 | 3259 |
| ARFGAP1 | 3224 |
| RAB29 | 3213 |
| RAB10 | 3205 |
| FEM1A | 3196 |
| RAB3D | 3155 |
| PPA1 | 3152 |
| TRAF6 | 3150 |
| CAPZA2 | 3143 |
| SPP2 | 3138 |
| B3GNT7 | 3122 |
| MUC13 | 3097 |
| SUMO2 | 3089 |
| PSMC3 | 3070 |
| FBXL18 | 3067 |
| GLB1 | 3064 |
| NDC1 | 3023 |
| NR3C2 | 2999 |
| HDAC4 | 2998 |
| PTCD3 | 2990 |
| MCRS1 | 2985 |
| CCT7 | 2974 |
| NSMCE4A | 2966 |
| MRPS35 | 2963 |
| GSN | 2952 |
| CALB1 | 2895 |
| DCTN3 | 2887 |
| USP4 | 2874 |
| PREB | 2868 |
| CCT4 | 2852 |
| PAPPA | 2849 |
| DCUN1D1 | 2843 |
| UGGT2 | 2839 |
| SEC61A2 | 2808 |
| MRPL15 | 2798 |
| USP49 | 2797 |
| MRPL53 | 2796 |
| RAB2B | 2784 |
| RAB6B | 2780 |
| PIAS3 | 2775 |
| ACTL6A | 2772 |
| RNF128 | 2768 |
| B3GNTL1 | 2766 |
| B4GALNT2 | 2758 |
| BTRC | 2757 |
| RPL21 | 2755 |
| MBOAT4 | 2719 |
| SOCS2 | 2710 |
| NUP133 | 2708 |
| MYRIP | 2692 |
| ALG13 | 2687 |
| MRPL58 | 2678 |
| PIGN | 2662 |
| CHD3 | 2661 |
| UBE2I | 2653 |
| FARS2 | 2645 |
| TNIP2 | 2640 |
| FN3K | 2638 |
| RPL15 | 2637 |
| NFKB2 | 2634 |
| SPSB2 | 2622 |
| WDTC1 | 2617 |
| LAMC1 | 2611 |
| MEN1 | 2581 |
| RAB6A | 2578 |
| TUBA8 | 2575 |
| CCNF | 2569 |
| TUBB2A | 2568 |
| UBA3 | 2562 |
| ARFGAP2 | 2547 |
| ARSK | 2519 |
| QSOX1 | 2518 |
| LMO7 | 2512 |
| ATP6AP2 | 2508 |
| DPM1 | 2494 |
| CUL5 | 2485 |
| EARS2 | 2477 |
| KLHL11 | 2475 |
| USP20 | 2470 |
| TUSC3 | 2465 |
| TADA3 | 2462 |
| ADAMTS4 | 2448 |
| GOSR2 | 2441 |
| AURKA | 2412 |
| TFPT | 2390 |
| CAPZB | 2376 |
| RPL3 | 2369 |
| PIGT | 2351 |
| ACHE | 2348 |
| NOP56 | 2332 |
| PSMB4 | 2330 |
| FBXL12 | 2320 |
| RCE1 | 2289 |
| RPL17 | 2280 |
| TUBB6 | 2268 |
| CPM | 2250 |
| ASB8 | 2243 |
| TSFM | 2236 |
| ADAMTSL5 | 2224 |
| UBXN7 | 2192 |
| RPS8 | 2190 |
| ALG8 | 2188 |
| SUMF2 | 2158 |
| NSMCE3 | 2144 |
| SPSB1 | 2118 |
| MAN2A1 | 2117 |
| PIGU | 2112 |
| AIMP2 | 2099 |
| MYSM1 | 2098 |
| VDAC1 | 2092 |
| TTLL9 | 2086 |
| MAN1A1 | 2084 |
| MUC20 | 2082 |
| CHCHD1 | 2069 |
| GNB3 | 2063 |
| PSMB1 | 2062 |
| MRPS9 | 2061 |
| EXOC4 | 2059 |
| PML | 2057 |
| PDCL | 2055 |
| MRPL28 | 2037 |
| KLHL5 | 2025 |
| ARFGEF2 | 2008 |
| RPL12 | 2000 |
| USP10 | 1999 |
| CEACAM5 | 1981 |
| UBE2Z | 1959 |
| MDM2 | 1942 |
| KDELR3 | 1922 |
| DAP3 | 1917 |
| RPS25 | 1901 |
| CAMKMT | 1898 |
| TCF7L2 | 1893 |
| DDX58 | 1883 |
| RAB12 | 1872 |
| PIGY | 1867 |
| FBXO7 | 1865 |
| UBE2D2 | 1857 |
| UAP1 | 1828 |
| EIF3F | 1821 |
| PSMA7 | 1820 |
| SENP1 | 1811 |
| MRPL18 | 1806 |
| TBCE | 1805 |
| RAB11B | 1793 |
| FBXL13 | 1783 |
| EIF3H | 1763 |
| MRPS17 | 1758 |
| FBXW9 | 1747 |
| LMCD1 | 1745 |
| COPS7B | 1713 |
| EEF2KMT | 1703 |
| SEC22B | 1690 |
| PHC3 | 1660 |
| GALNT1 | 1659 |
| GALNT13 | 1646 |
| F5 | 1638 |
| RNF146 | 1622 |
| GP2 | 1595 |
| IKBKE | 1593 |
| GNAQ | 1588 |
| L3MBTL2 | 1567 |
| MRPS5 | 1563 |
| MRPS14 | 1561 |
| SMC1A | 1560 |
| COPZ1 | 1554 |
| UBC | 1551 |
| MRPL20 | 1542 |
| EXOC2 | 1496 |
| C1GALT1 | 1485 |
| PSMB5 | 1484 |
| MRPL9 | 1463 |
| F8 | 1460 |
| PEX13 | 1454 |
| SFTPB | 1453 |
| UBE2G2 | 1451 |
| TTLL5 | 1443 |
| ING2 | 1437 |
| RPL13 | 1426 |
| BST1 | 1408 |
| COMMD8 | 1404 |
| GNB5 | 1388 |
| CALM1 | 1340 |
| TUBA4A | 1335 |
| GCNT1 | 1328 |
| TOMM20 | 1324 |
| YARS2 | 1313 |
| MTIF2 | 1307 |
| PRSS23 | 1288 |
| LRRC49 | 1273 |
| PPP6R3 | 1271 |
| MSRB3 | 1267 |
| ELOC | 1265 |
| RNF7 | 1249 |
| F2 | 1246 |
| PIGS | 1243 |
| ASB18 | 1231 |
| TAF10 | 1223 |
| GOSR1 | 1215 |
| APH1A | 1209 |
| FBXL15 | 1200 |
| TRAF2 | 1180 |
| RAD21 | 1178 |
| OTUD7A | 1152 |
| TTLL12 | 1140 |
| NCSTN | 1137 |
| NEDD8 | 1131 |
| SKP1 | 1117 |
| NRIP1 | 1114 |
| TPR | 1105 |
| CCT6B | 1100 |
| EEF1A2 | 1086 |
| MRPS18A | 1085 |
| SARS2 | 1066 |
| WDR48 | 1063 |
| NR2C1 | 1052 |
| UBA1 | 1021 |
| INHA | 1010 |
| BIRC2 | 1007 |
| RPL5 | 1001 |
| LRR1 | 1000 |
| LAMB2 | 978 |
| PAX6 | 967 |
| SCFD1 | 960 |
| MRPS10 | 959 |
| NANP | 957 |
| MRPL40 | 956 |
| MRPL13 | 955 |
| BET1 | 896 |
| WDR61 | 889 |
| PSMD11 | 879 |
| UCHL5 | 875 |
| ALG9 | 865 |
| EIF2B4 | 862 |
| TUBB3 | 858 |
| NAPB | 853 |
| PSMB10 | 838 |
| RPS26 | 827 |
| MRPL50 | 818 |
| DCUN1D4 | 815 |
| UBE2R2 | 790 |
| COMMD2 | 774 |
| SEC23IP | 767 |
| EIF3C | 764 |
| PIAS2 | 761 |
| RAB18 | 760 |
| UBE2K | 750 |
| TRAF3 | 729 |
| PEX5 | 707 |
| CUL2 | 703 |
| HDAC2 | 693 |
| NUP160 | 683 |
| USP25 | 676 |
| DCTN6 | 666 |
| SUZ12 | 664 |
| EXOC5 | 650 |
| RPL31 | 638 |
| NUP62 | 618 |
| LYPD3 | 613 |
| FBXW2 | 602 |
| OTUB1 | 600 |
| ANK3 | 591 |
| EIF1AX | 563 |
| RAB30 | 562 |
| VDAC3 | 561 |
| PIAS1 | 560 |
| POFUT2 | 542 |
| B4GALT1 | 540 |
| MITF | 519 |
| RPL9 | 509 |
| BGLAP | 475 |
| TRAPPC5 | 470 |
| APOA4 | 444 |
| KLHL25 | 441 |
| RPL22L1 | 439 |
| CNIH1 | 416 |
| ERO1A | 403 |
| INO80C | 380 |
| NR1H2 | 373 |
| RPS3A | 369 |
| KCTD6 | 368 |
| MTIF3 | 355 |
| ANO8 | 350 |
| RPS27 | 312 |
| EIF2B1 | 293 |
| SDC2 | 289 |
| FBXO30 | 270 |
| PSMA6 | 261 |
| USP7 | 258 |
| HDAC7 | 254 |
| RNF135 | 247 |
| COMMD10 | 233 |
| DOLK | 213 |
| FEM1B | 209 |
| RBBP5 | 204 |
| EXOC8 | 189 |
| MRPL19 | 185 |
| OTOA | 171 |
| FBXO2 | 158 |
| PIGX | 124 |
| CSF2RA | 94 |
| HDAC3 | 84 |
| BTBD1 | 81 |
| CTBP1 | 73 |
| AHSG | 62 |
| COPS4 | 51 |
| FBXO10 | 43 |
| RANBP2 | 9 |
| COMMD4 | 7 |
Calnexin/calreticulin cycle
| 127 | |
|---|---|
| set | Calnexin/calreticulin cycle |
| setSize | 25 |
| pANOVA | 0.000369 |
| s.dist | 0.412 |
| p.adjustANOVA | 0.0131 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CALR | 14529 |
| SEL1L | 14508 |
| SYVN1 | 14485 |
| EDEM1 | 14479 |
| CANX | 14462 |
| PDIA3 | 14454 |
| DERL2 | 14399 |
| OS9 | 14320 |
| UGGT1 | 14270 |
| RNF5 | 13745 |
| RNF185 | 13291 |
| RNF103 | 12848 |
| PRKCSH | 12463 |
| EDEM2 | 11628 |
| UBA52 | 10707 |
| UBB | 9013 |
| MAN1B1 | 7534 |
| RNF139 | 6382 |
| RPS27A | 5776 |
| AMFR | 5612 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CALR | 14529 |
| SEL1L | 14508 |
| SYVN1 | 14485 |
| EDEM1 | 14479 |
| CANX | 14462 |
| PDIA3 | 14454 |
| DERL2 | 14399 |
| OS9 | 14320 |
| UGGT1 | 14270 |
| RNF5 | 13745 |
| RNF185 | 13291 |
| RNF103 | 12848 |
| PRKCSH | 12463 |
| EDEM2 | 11628 |
| UBA52 | 10707 |
| UBB | 9013 |
| MAN1B1 | 7534 |
| RNF139 | 6382 |
| RPS27A | 5776 |
| AMFR | 5612 |
| GANAB | 5417 |
| EDEM3 | 3904 |
| TRIM13 | 3695 |
| UGGT2 | 2839 |
| UBC | 1551 |
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
| 425 | |
|---|---|
| set | Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation |
| setSize | 31 |
| pANOVA | 0.00037 |
| s.dist | 0.37 |
| p.adjustANOVA | 0.0131 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CNN2 | 14383 |
| SOD2 | 14367 |
| SNRPA1 | 14316 |
| HNRNPF | 13925 |
| LMNB1 | 13707 |
| HSPA9 | 13667 |
| RALA | 13623 |
| HNRNPA2B1 | 13444 |
| ARF1 | 12642 |
| CFL1 | 12075 |
| PITPNA | 11779 |
| ANXA2 | 11716 |
| TALDO1 | 11703 |
| PSME2 | 11555 |
| SOD1 | 10975 |
| MIF | 10935 |
| PAK2 | 10458 |
| CAPZA1 | 10272 |
| TCP1 | 10050 |
| GSTA2 | 9767 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CNN2 | 14383 |
| SOD2 | 14367 |
| SNRPA1 | 14316 |
| HNRNPF | 13925 |
| LMNB1 | 13707 |
| HSPA9 | 13667 |
| RALA | 13623 |
| HNRNPA2B1 | 13444 |
| ARF1 | 12642 |
| CFL1 | 12075 |
| PITPNA | 11779 |
| ANXA2 | 11716 |
| TALDO1 | 11703 |
| PSME2 | 11555 |
| SOD1 | 10975 |
| MIF | 10935 |
| PAK2 | 10458 |
| CAPZA1 | 10272 |
| TCP1 | 10050 |
| GSTA2 | 9767 |
| PPIA | 9393 |
| RPLP0 | 9067 |
| AIP | 9029 |
| MTAP | 7801 |
| RAP1B | 6830 |
| PDCD4 | 6023 |
| CDC42 | 4489 |
| GSTO1 | 4401 |
| BOLA2 | 2230 |
| HNRNPDL | 1890 |
| LCP1 | 1834 |
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
| 922 | |
|---|---|
| set | RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function |
| setSize | 34 |
| pANOVA | 0.000408 |
| s.dist | 0.35 |
| p.adjustANOVA | 0.014 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RUNX1 | 14359 |
| SETD1A | 13864 |
| SETD1B | 13746 |
| KMT2B | 13684 |
| KMT2C | 13569 |
| EP300 | 13485 |
| CBFB | 13329 |
| DPY30 | 13091 |
| KMT2D | 13087 |
| PRMT6 | 12591 |
| AGO4 | 12561 |
| SIN3A | 12373 |
| MOV10 | 12217 |
| AGO3 | 12205 |
| ZFPM1 | 12174 |
| NFE2 | 11657 |
| THBS1 | 11408 |
| TNRC6C | 10180 |
| KAT2B | 10158 |
| H2AFX | 10131 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RUNX1 | 14359 |
| SETD1A | 13864 |
| SETD1B | 13746 |
| KMT2B | 13684 |
| KMT2C | 13569 |
| EP300 | 13485 |
| CBFB | 13329 |
| DPY30 | 13091 |
| KMT2D | 13087 |
| PRMT6 | 12591 |
| AGO4 | 12561 |
| SIN3A | 12373 |
| MOV10 | 12217 |
| AGO3 | 12205 |
| ZFPM1 | 12174 |
| NFE2 | 11657 |
| THBS1 | 11408 |
| TNRC6C | 10180 |
| KAT2B | 10158 |
| H2AFX | 10131 |
| PRMT1 | 9055 |
| ASH2L | 8974 |
| TNRC6B | 8904 |
| AGO1 | 8173 |
| SIN3B | 7646 |
| NR4A3 | 7584 |
| KMT2A | 6772 |
| HDAC1 | 5563 |
| KMT2E | 5551 |
| MYL9 | 5218 |
| WDR5 | 4953 |
| TNRC6A | 3580 |
| ITGA2B | 1391 |
| RBBP5 | 204 |
Cell Cycle, Mitotic
| 141 | |
|---|---|
| set | Cell Cycle, Mitotic |
| setSize | 478 |
| pANOVA | 0.00059 |
| s.dist | 0.0923 |
| p.adjustANOVA | 0.0197 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| GINS1 | 14342 |
| CDC6 | 14067 |
| SEC13 | 14049 |
| CDK1 | 14027 |
| HMMR | 14001 |
| LPIN3 | 13949 |
| LPIN2 | 13908 |
| NDC80 | 13840 |
| CABLES1 | 13825 |
| PSMF1 | 13810 |
| NUDC | 13808 |
| UBE2C | 13793 |
| LMNB1 | 13707 |
| NUP37 | 13706 |
| E2F1 | 13694 |
| TUBA1B | 13681 |
| CHMP4C | 13640 |
| KNL1 | 13621 |
| MAD2L1 | 13616 |
| VRK2 | 13580 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| GINS1 | 14342 |
| CDC6 | 14067 |
| SEC13 | 14049 |
| CDK1 | 14027 |
| HMMR | 14001 |
| LPIN3 | 13949 |
| LPIN2 | 13908 |
| NDC80 | 13840 |
| CABLES1 | 13825 |
| PSMF1 | 13810 |
| NUDC | 13808 |
| UBE2C | 13793 |
| LMNB1 | 13707 |
| NUP37 | 13706 |
| E2F1 | 13694 |
| TUBA1B | 13681 |
| CHMP4C | 13640 |
| KNL1 | 13621 |
| MAD2L1 | 13616 |
| VRK2 | 13580 |
| ANKLE2 | 13567 |
| LIN52 | 13530 |
| HAUS5 | 13521 |
| MYBL2 | 13519 |
| CENPK | 13518 |
| SPC24 | 13498 |
| RAN | 13497 |
| EP300 | 13485 |
| NUF2 | 13470 |
| PSME4 | 13450 |
| NEDD1 | 13438 |
| BUB1B | 13431 |
| PSMD2 | 13423 |
| MCM5 | 13415 |
| HAUS4 | 13402 |
| TMPO | 13363 |
| PRIM1 | 13355 |
| RPA2 | 13354 |
| LEMD2 | 13339 |
| DHFR | 13334 |
| KPNB1 | 13324 |
| MIS12 | 13304 |
| POM121 | 13281 |
| POLE4 | 13279 |
| DSN1 | 13258 |
| GINS2 | 13245 |
| AURKB | 13190 |
| TOP2A | 13176 |
| TK1 | 13137 |
| TNPO1 | 13094 |
| CDC25C | 13084 |
| NUP210 | 13025 |
| MCM6 | 12996 |
| TUBA1C | 12940 |
| GINS3 | 12937 |
| TUBB4B | 12934 |
| MCM2 | 12926 |
| SPDL1 | 12856 |
| POLA2 | 12805 |
| KNTC1 | 12758 |
| CDCA8 | 12700 |
| CCNB2 | 12689 |
| POM121C | 12687 |
| MAPK3 | 12684 |
| MCM4 | 12667 |
| ESCO2 | 12665 |
| CKAP5 | 12651 |
| PRIM2 | 12596 |
| CCNA2 | 12587 |
| GINS4 | 12516 |
| PSMD6 | 12502 |
| CLIP1 | 12494 |
| PCNA | 12452 |
| SKA2 | 12421 |
| E2F2 | 12251 |
| KIF2A | 12231 |
| PTTG1 | 12222 |
| PSMA2 | 12203 |
| ITGB3BP | 12199 |
| PCNT | 12160 |
| RPA3 | 12149 |
| SIRT2 | 12121 |
| CNTRL | 12110 |
| PPP2R5A | 12088 |
| PSMA1 | 12052 |
| CSNK1D | 12038 |
| KIF23 | 12032 |
| ANAPC16 | 12018 |
| RCC2 | 12011 |
| CDC25B | 11958 |
| OPTN | 11914 |
| NDEL1 | 11904 |
| ANAPC7 | 11895 |
| ZWILCH | 11891 |
| CENPH | 11884 |
| LIG1 | 11811 |
| PPP2R2D | 11809 |
| CCP110 | 11807 |
| SSNA1 | 11800 |
| CDT1 | 11791 |
| PSMC1 | 11724 |
| DYRK1A | 11712 |
| MCPH1 | 11698 |
| PSMD3 | 11655 |
| SMC2 | 11646 |
| LPIN1 | 11643 |
| CDC23 | 11639 |
| PKMYT1 | 11586 |
| NUP107 | 11561 |
| PSME2 | 11555 |
| ANAPC10 | 11551 |
| NEK6 | 11540 |
| DYNLL2 | 11507 |
| GORASP2 | 11463 |
| CDK7 | 11458 |
| AJUBA | 11454 |
| ZWINT | 11400 |
| NUP35 | 11387 |
| KIF2C | 11386 |
| PSMD14 | 11371 |
| CENPI | 11351 |
| CDC25A | 11334 |
| RAB2A | 11326 |
| SKP2 | 11323 |
| KIF20A | 11285 |
| PSMD1 | 11280 |
| SPAST | 11237 |
| CENPQ | 11227 |
| CHMP6 | 11222 |
| NCAPH | 11214 |
| GOLGA2 | 11209 |
| NEK9 | 11195 |
| CTDNEP1 | 11193 |
| TUBG1 | 11173 |
| NUP205 | 11144 |
| CDC7 | 11135 |
| POLD1 | 11069 |
| NUP93 | 11067 |
| CEP192 | 11035 |
| SMC4 | 11020 |
| CETN2 | 11018 |
| CENPJ | 11011 |
| CEP290 | 10987 |
| GMNN | 10951 |
| TUBG2 | 10942 |
| CDK5RAP2 | 10940 |
| PPP2CA | 10917 |
| ACTR1A | 10903 |
| NCAPG | 10863 |
| TYMS | 10848 |
| PPP2R5B | 10834 |
| PPP2R2A | 10808 |
| GSK3B | 10767 |
| CENPC | 10756 |
| CDC20 | 10732 |
| NUMA1 | 10724 |
| UBA52 | 10707 |
| MAPK1 | 10705 |
| CDK4 | 10698 |
| E2F6 | 10689 |
| BORA | 10684 |
| CSNK2A1 | 10637 |
| KMT5A | 10628 |
| CHMP4B | 10594 |
| CCNH | 10565 |
| RPA1 | 10563 |
| ENSA | 10545 |
| CENPE | 10538 |
| NUP188 | 10521 |
| RFC1 | 10506 |
| ANAPC15 | 10442 |
| PSMB9 | 10430 |
| CDCA5 | 10400 |
| PSMB6 | 10326 |
| PSMC6 | 10307 |
| CDKN2D | 10296 |
| MAX | 10232 |
| PSMC4 | 10196 |
| NEK2 | 10138 |
| NUP88 | 10134 |
| H2AFX | 10131 |
| RFC3 | 10111 |
| PPP2R1A | 10064 |
| PLK4 | 10056 |
| NUP50 | 10047 |
| INCENP | 10005 |
| ESPL1 | 9994 |
| SGO2 | 9987 |
| CENPM | 9951 |
| KIF18A | 9884 |
| PSMD9 | 9853 |
| BIRC5 | 9771 |
| CEP78 | 9704 |
| B9D2 | 9695 |
| TUBB | 9694 |
| PSMD5 | 9676 |
| AKAP9 | 9671 |
| ORC3 | 9670 |
| CSNK2A2 | 9641 |
| PPP2CB | 9606 |
| CEP152 | 9577 |
| PLK1 | 9548 |
| MCM10 | 9536 |
| SEH1L | 9474 |
| SFI1 | 9420 |
| POLA1 | 9387 |
| PSMD7 | 9371 |
| HSP90AB1 | 9363 |
| PSMD10 | 9356 |
| POLD2 | 9350 |
| PSMB7 | 9253 |
| CEP76 | 9240 |
| TFDP2 | 9210 |
| CEP57 | 9181 |
| SKA1 | 9144 |
| FOXM1 | 9137 |
| NUP155 | 9102 |
| MCM3 | 9054 |
| CDK6 | 9023 |
| UBB | 9013 |
| GTSE1 | 8986 |
| CLASP2 | 8977 |
| CENPT | 8952 |
| VRK1 | 8944 |
| TUBA1A | 8932 |
| PSMA4 | 8902 |
| RFC4 | 8885 |
| RBL1 | 8842 |
| CEP41 | 8824 |
| HAUS6 | 8791 |
| PPP2R1B | 8759 |
| CUL1 | 8725 |
| PPP1R12B | 8721 |
| MCM8 | 8710 |
| PSMD4 | 8670 |
| PSMC5 | 8646 |
| CENPA | 8625 |
| AHCTF1 | 8598 |
| NINL | 8595 |
| ZW10 | 8564 |
| POLE2 | 8557 |
| POLD3 | 8459 |
| DCTN2 | 8375 |
| CSNK2B | 8368 |
| RAE1 | 8335 |
| RFC5 | 8324 |
| CENPU | 8282 |
| MAD1L1 | 8264 |
| DYNC1LI2 | 8235 |
| PSMD12 | 8163 |
| CCND2 | 8117 |
| PSME3 | 8052 |
| CDKN2C | 8034 |
| TPX2 | 8033 |
| MZT2B | 8028 |
| PHF8 | 8025 |
| MAPRE1 | 8020 |
| FBXW11 | 7986 |
| CENPF | 7980 |
| TUBB2B | 7952 |
| NUP85 | 7946 |
| NUP98 | 7940 |
| NEK7 | 7858 |
| LMNA | 7854 |
| RBX1 | 7850 |
| ORC2 | 7840 |
| CDK2 | 7809 |
| PPP1CB | 7685 |
| TUBB8 | 7651 |
| DYNC1H1 | 7639 |
| CDKN1A | 7569 |
| SRC | 7516 |
| RRM2 | 7504 |
| ANAPC5 | 7485 |
| USO1 | 7413 |
| EMD | 7404 |
| RFC2 | 7371 |
| RAB1B | 7340 |
| HDAC8 | 7301 |
| BANF1 | 7227 |
| PPP1CC | 7149 |
| PDS5A | 7116 |
| UBE2E1 | 7102 |
| CDKN2A | 7056 |
| STAG1 | 7037 |
| NCAPD3 | 6972 |
| RAB1A | 6957 |
| RBBP4 | 6938 |
| POLD4 | 6907 |
| FBXO5 | 6788 |
| UBE2D1 | 6734 |
| NSL1 | 6722 |
| FKBPL | 6720 |
| HAUS8 | 6695 |
| PPP2R3B | 6689 |
| BLZF1 | 6684 |
| LBR | 6666 |
| PPME1 | 6623 |
| RANGAP1 | 6615 |
| E2F4 | 6609 |
| NIPBL | 6603 |
| SEM1 | 6566 |
| HAUS3 | 6563 |
| BUB1 | 6536 |
| DNA2 | 6486 |
| TUBGCP5 | 6445 |
| CEP164 | 6425 |
| PSMA3 | 6422 |
| NUP54 | 6371 |
| SUMO1 | 6365 |
| PTK6 | 6358 |
| LYN | 6328 |
| CSNK1E | 6238 |
| AKT1 | 6160 |
| PDS5B | 6136 |
| HAUS7 | 6092 |
| PSMD8 | 6091 |
| DBF4 | 6080 |
| CC2D1B | 6039 |
| NCAPD2 | 5978 |
| TAOK1 | 5951 |
| TUBGCP3 | 5843 |
| MZT1 | 5824 |
| DYNC1I2 | 5783 |
| RPS27A | 5776 |
| AAAS | 5701 |
| JAK2 | 5664 |
| PSMA5 | 5657 |
| MASTL | 5640 |
| CCND3 | 5565 |
| HDAC1 | 5563 |
| STAG2 | 5443 |
| TUBGCP4 | 5424 |
| NUP43 | 5410 |
| ODF2 | 5391 |
| NCAPH2 | 5381 |
| TFDP1 | 5361 |
| PSMD13 | 5353 |
| CCNE1 | 5315 |
| PPP2R5C | 5293 |
| CKS1B | 5274 |
| WEE1 | 5244 |
| DYNC1LI1 | 5237 |
| TUBB1 | 5236 |
| NUP153 | 5230 |
| CHMP7 | 5197 |
| LCMT1 | 5160 |
| PMF1 | 5043 |
| PSMC2 | 4948 |
| PCM1 | 4925 |
| SMC3 | 4924 |
| MCM7 | 4863 |
| PSME1 | 4861 |
| DYNLL1 | 4853 |
| PRKCA | 4709 |
| ORC5 | 4688 |
| RAB8A | 4658 |
| NUP58 | 4603 |
| VPS4A | 4592 |
| RCC1 | 4473 |
| PPP2R5D | 4385 |
| CENPN | 4377 |
| ORC1 | 4368 |
| LIN54 | 4306 |
| LIN9 | 4167 |
| CCNE2 | 4152 |
| TP53 | 4144 |
| IST1 | 4111 |
| SET | 4107 |
| AKT2 | 3993 |
| POLE | 3985 |
| NUP214 | 3957 |
| ABL1 | 3944 |
| PSMB3 | 3928 |
| SGO1 | 3925 |
| ANAPC1 | 3900 |
| UBE2S | 3839 |
| TUBGCP6 | 3832 |
| XPO1 | 3824 |
| ORC6 | 3780 |
| GORASP1 | 3727 |
| MYC | 3708 |
| PSMB2 | 3678 |
| ORC4 | 3669 |
| CEP250 | 3590 |
| NDE1 | 3555 |
| CDC45 | 3490 |
| PRKACA | 3407 |
| CDKN2B | 3352 |
| ANAPC2 | 3349 |
| DCTN1 | 3338 |
| RBL2 | 3324 |
| TUBGCP2 | 3172 |
| ANAPC11 | 3134 |
| CDC27 | 3103 |
| HAUS1 | 3101 |
| CLASP1 | 3071 |
| PSMC3 | 3070 |
| FBXL18 | 3067 |
| NDC1 | 3023 |
| CEP135 | 2992 |
| DCTN3 | 2887 |
| BTRC | 2757 |
| CENPP | 2725 |
| NUP133 | 2708 |
| UBE2I | 2653 |
| ESCO1 | 2579 |
| TUBA8 | 2575 |
| TUBB2A | 2568 |
| CHMP3 | 2417 |
| AURKA | 2412 |
| PSMB4 | 2330 |
| CDC16 | 2309 |
| POLE3 | 2308 |
| LIN37 | 2294 |
| BUB3 | 2290 |
| TUBB6 | 2268 |
| CEP131 | 2251 |
| CHMP2A | 2222 |
| SDCCAG8 | 2210 |
| PPP1R12A | 2182 |
| E2F5 | 2102 |
| HSP90AA1 | 2096 |
| YWHAG | 2081 |
| PSMB1 | 2062 |
| CEP70 | 1965 |
| CEP72 | 1949 |
| LEMD3 | 1868 |
| PSMA7 | 1820 |
| CHMP2B | 1797 |
| CHMP4A | 1779 |
| HAUS2 | 1773 |
| MAU2 | 1767 |
| CCNB1 | 1641 |
| CDK11B | 1640 |
| CDKN1B | 1590 |
| SMC1A | 1560 |
| NME7 | 1556 |
| UBC | 1551 |
| NCAPG2 | 1539 |
| CENPL | 1495 |
| PSMB5 | 1484 |
| TUBA4A | 1335 |
| ARPP19 | 1262 |
| RAD21 | 1178 |
| SKP1 | 1117 |
| TPR | 1105 |
| CDK11A | 1049 |
| CNEP1R1 | 972 |
| RB1 | 925 |
| PSMD11 | 879 |
| E2F3 | 876 |
| TUBB3 | 858 |
| CEP63 | 854 |
| PSMB10 | 838 |
| CENPO | 820 |
| FEN1 | 721 |
| PHLDA1 | 720 |
| NUP160 | 683 |
| WAPL | 620 |
| NUP62 | 618 |
| ANAPC4 | 595 |
| MZT2A | 582 |
| ALMS1 | 578 |
| PPP2R5E | 554 |
| MNAT1 | 420 |
| CDC26 | 402 |
| FZR1 | 397 |
| RPS27 | 312 |
| CCND1 | 277 |
| PSMA6 | 261 |
| YWHAE | 253 |
| CDC14A | 249 |
| PAFAH1B1 | 237 |
| ERCC6L | 86 |
| OFD1 | 83 |
| EML4 | 66 |
| RANBP2 | 9 |
Synthesis of substrates in N-glycan biosythesis
| 1196 | |
|---|---|
| set | Synthesis of substrates in N-glycan biosythesis |
| setSize | 49 |
| pANOVA | 0.000601 |
| s.dist | 0.283 |
| p.adjustANOVA | 0.0197 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SLC17A5 | 14434 |
| GFPT1 | 14406 |
| MVD | 14220 |
| NANS | 14204 |
| GMPPB | 14096 |
| ST3GAL4 | 14033 |
| NEU1 | 13953 |
| ST6GALNAC4 | 13912 |
| SLC35C1 | 13821 |
| NEU3 | 13653 |
| ALG5 | 13488 |
| NUS1 | 13362 |
| NEU4 | 13335 |
| GMPPA | 13267 |
| CTSA | 13149 |
| ST3GAL1 | 12408 |
| RENBP | 12130 |
| GNE | 11517 |
| PGM3 | 11367 |
| ST3GAL3 | 11257 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SLC17A5 | 14434 |
| GFPT1 | 14406 |
| MVD | 14220 |
| NANS | 14204 |
| GMPPB | 14096 |
| ST3GAL4 | 14033 |
| NEU1 | 13953 |
| ST6GALNAC4 | 13912 |
| SLC35C1 | 13821 |
| NEU3 | 13653 |
| ALG5 | 13488 |
| NUS1 | 13362 |
| NEU4 | 13335 |
| GMPPA | 13267 |
| CTSA | 13149 |
| ST3GAL1 | 12408 |
| RENBP | 12130 |
| GNE | 11517 |
| PGM3 | 11367 |
| ST3GAL3 | 11257 |
| PMM2 | 10956 |
| CMAS | 10871 |
| FPGT | 10685 |
| DOLPP1 | 10517 |
| AMDHD2 | 10267 |
| ST6GALNAC6 | 10212 |
| ST3GAL5 | 9630 |
| MPI | 9596 |
| ST3GAL2 | 9594 |
| SRD5A3 | 9027 |
| NUDT14 | 8814 |
| NAGK | 8559 |
| SLC35A1 | 7418 |
| GMDS | 7053 |
| ST3GAL6 | 6829 |
| DPM3 | 6189 |
| PMM1 | 5521 |
| FUOM | 4976 |
| DHDDS | 4636 |
| GNPNAT1 | 4628 |
| ST8SIA1 | 4428 |
| DPM2 | 4373 |
| ST6GAL1 | 3739 |
| ST8SIA5 | 3583 |
| GLB1 | 3064 |
| DPM1 | 2494 |
| UAP1 | 1828 |
| NANP | 957 |
| DOLK | 213 |
Interleukin-12 signaling
| 541 | |
|---|---|
| set | Interleukin-12 signaling |
| setSize | 38 |
| pANOVA | 0.000767 |
| s.dist | 0.315 |
| p.adjustANOVA | 0.0237 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CNN2 | 14383 |
| SOD2 | 14367 |
| SNRPA1 | 14316 |
| P4HB | 14170 |
| HNRNPF | 13925 |
| LMNB1 | 13707 |
| HSPA9 | 13667 |
| RALA | 13623 |
| HNRNPA2B1 | 13444 |
| ARF1 | 12642 |
| CFL1 | 12075 |
| PITPNA | 11779 |
| ANXA2 | 11716 |
| TALDO1 | 11703 |
| PSME2 | 11555 |
| SOD1 | 10975 |
| MIF | 10935 |
| JAK1 | 10468 |
| PAK2 | 10458 |
| CAPZA1 | 10272 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CNN2 | 14383 |
| SOD2 | 14367 |
| SNRPA1 | 14316 |
| P4HB | 14170 |
| HNRNPF | 13925 |
| LMNB1 | 13707 |
| HSPA9 | 13667 |
| RALA | 13623 |
| HNRNPA2B1 | 13444 |
| ARF1 | 12642 |
| CFL1 | 12075 |
| PITPNA | 11779 |
| ANXA2 | 11716 |
| TALDO1 | 11703 |
| PSME2 | 11555 |
| SOD1 | 10975 |
| MIF | 10935 |
| JAK1 | 10468 |
| PAK2 | 10458 |
| CAPZA1 | 10272 |
| TCP1 | 10050 |
| GSTA2 | 9767 |
| TYK2 | 9579 |
| PPIA | 9393 |
| RPLP0 | 9067 |
| AIP | 9029 |
| IL12A | 8182 |
| MTAP | 7801 |
| RAP1B | 6830 |
| PDCD4 | 6023 |
| VAMP7 | 5793 |
| JAK2 | 5664 |
| CDC42 | 4489 |
| GSTO1 | 4401 |
| BOLA2 | 2230 |
| HNRNPDL | 1890 |
| LCP1 | 1834 |
| IL12RB1 | 832 |
NOTCH4 Intracellular Domain Regulates Transcription
| 686 | |
|---|---|
| set | NOTCH4 Intracellular Domain Regulates Transcription |
| setSize | 15 |
| pANOVA | 0.000777 |
| s.dist | 0.501 |
| p.adjustANOVA | 0.0237 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| ACTA2 | 14438 |
| MAML1 | 14179 |
| HES1 | 14121 |
| EP300 | 13485 |
| MAML2 | 13122 |
| SMAD3 | 12871 |
| NOTCH2 | 11869 |
| SNW1 | 11762 |
| KAT2B | 10158 |
| KAT2A | 9597 |
| RBPJ | 9099 |
| NOTCH1 | 8281 |
| CREBBP | 8214 |
| HEY1 | 8169 |
| FLT4 | 4214 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ACTA2 | 14438 |
| MAML1 | 14179 |
| HES1 | 14121 |
| EP300 | 13485 |
| MAML2 | 13122 |
| SMAD3 | 12871 |
| NOTCH2 | 11869 |
| SNW1 | 11762 |
| KAT2B | 10158 |
| KAT2A | 9597 |
| RBPJ | 9099 |
| NOTCH1 | 8281 |
| CREBBP | 8214 |
| HEY1 | 8169 |
| FLT4 | 4214 |
Signaling by Interleukins
| 1117 | |
|---|---|
| set | Signaling by Interleukins |
| setSize | 315 |
| pANOVA | 0.000788 |
| s.dist | 0.11 |
| p.adjustANOVA | 0.0237 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| HSP90B1 | 14514 |
| SOCS3 | 14476 |
| CANX | 14462 |
| IL21R | 14424 |
| MAP3K8 | 14418 |
| CSF3R | 14395 |
| CNN2 | 14383 |
| SOD2 | 14367 |
| SQSTM1 | 14347 |
| SNRPA1 | 14316 |
| JAK3 | 14295 |
| STX3 | 14279 |
| IL17RB | 14244 |
| TGFB1 | 14241 |
| SHC1 | 14209 |
| CCL20 | 14171 |
| P4HB | 14170 |
| HNRNPF | 13925 |
| IRAK2 | 13893 |
| CSF1 | 13888 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HSP90B1 | 14514 |
| SOCS3 | 14476 |
| CANX | 14462 |
| IL21R | 14424 |
| MAP3K8 | 14418 |
| CSF3R | 14395 |
| CNN2 | 14383 |
| SOD2 | 14367 |
| SQSTM1 | 14347 |
| SNRPA1 | 14316 |
| JAK3 | 14295 |
| STX3 | 14279 |
| IL17RB | 14244 |
| TGFB1 | 14241 |
| SHC1 | 14209 |
| CCL20 | 14171 |
| P4HB | 14170 |
| HNRNPF | 13925 |
| IRAK2 | 13893 |
| CSF1 | 13888 |
| PSMF1 | 13810 |
| IL1RN | 13768 |
| SOCS5 | 13766 |
| LMNB1 | 13707 |
| RAPGEF1 | 13680 |
| HSPA9 | 13667 |
| TOLLIP | 13662 |
| RALA | 13623 |
| DUSP3 | 13608 |
| RORC | 13571 |
| APP | 13532 |
| NFKBIB | 13495 |
| MAPKAPK2 | 13468 |
| PSME4 | 13450 |
| HNRNPA2B1 | 13444 |
| NFKBIA | 13427 |
| PSMD2 | 13423 |
| BCL2L1 | 13271 |
| CEBPD | 13165 |
| TIMP1 | 13158 |
| PTPN18 | 13128 |
| LCK | 13069 |
| PTK2B | 13043 |
| ATF2 | 12933 |
| SMAD3 | 12871 |
| TAB1 | 12789 |
| MAPK3 | 12684 |
| LAMA5 | 12680 |
| ARF1 | 12642 |
| DUSP4 | 12556 |
| STAT5B | 12541 |
| PTPN6 | 12513 |
| PSMD6 | 12502 |
| IKBKG | 12493 |
| PTPN23 | 12460 |
| IL1R1 | 12430 |
| ITGB2 | 12388 |
| RORA | 12360 |
| IL34 | 12233 |
| PSMA2 | 12203 |
| RIPK2 | 12158 |
| MAPKAPK3 | 12147 |
| CFL1 | 12075 |
| ELK1 | 12060 |
| PSMA1 | 12052 |
| CBL | 12008 |
| STAT1 | 11938 |
| CRK | 11901 |
| PITPNA | 11779 |
| PSMC1 | 11724 |
| ANXA2 | 11716 |
| TALDO1 | 11703 |
| MAP3K3 | 11679 |
| PSMD3 | 11655 |
| CASP1 | 11631 |
| CD4 | 11557 |
| PSME2 | 11555 |
| IRS2 | 11497 |
| CISH | 11440 |
| CLCF1 | 11424 |
| SOS2 | 11402 |
| PSMD14 | 11371 |
| MYD88 | 11305 |
| PSMD1 | 11280 |
| PTPN12 | 11236 |
| CASP3 | 11107 |
| PELI1 | 11028 |
| EBI3 | 10994 |
| SOD1 | 10975 |
| MIF | 10935 |
| FOS | 10931 |
| TBK1 | 10919 |
| PPP2CA | 10917 |
| IL10RB | 10890 |
| LBP | 10799 |
| VAMP2 | 10744 |
| UBA52 | 10707 |
| MAPK1 | 10705 |
| HMGB1 | 10552 |
| JAK1 | 10468 |
| PAK2 | 10458 |
| IL6R | 10440 |
| PSMB9 | 10430 |
| ATF1 | 10407 |
| NOD1 | 10348 |
| PSMB6 | 10326 |
| PSMC6 | 10307 |
| IL32 | 10276 |
| FOXO1 | 10275 |
| CAPZA1 | 10272 |
| GSDMD | 10266 |
| OSMR | 10214 |
| PSMC4 | 10196 |
| IL1RAP | 10146 |
| IL13RA1 | 10143 |
| PIK3CD | 10102 |
| PTPN9 | 10072 |
| PPP2R1A | 10064 |
| TCP1 | 10050 |
| STAT5A | 10000 |
| CD36 | 9953 |
| MMP2 | 9932 |
| UBE2V1 | 9900 |
| HSPA8 | 9895 |
| PSMD9 | 9853 |
| NKIRAS2 | 9777 |
| BIRC5 | 9771 |
| GSTA2 | 9767 |
| PSMD5 | 9676 |
| PPP2CB | 9606 |
| BATF | 9599 |
| TYK2 | 9579 |
| SOCS1 | 9561 |
| MAP2K4 | 9558 |
| PELI3 | 9505 |
| VEGFA | 9433 |
| PPIA | 9393 |
| PSMD7 | 9371 |
| PSMD10 | 9356 |
| MAP2K7 | 9311 |
| MAPK7 | 9270 |
| PIK3R1 | 9259 |
| PSMB7 | 9253 |
| IL18BP | 9182 |
| TNFRSF1A | 9118 |
| BCL6 | 9080 |
| RPLP0 | 9067 |
| AIP | 9029 |
| IL15RA | 9025 |
| UBB | 9013 |
| IL11RA | 8909 |
| PSMA4 | 8902 |
| HIF1A | 8807 |
| ITGB1 | 8760 |
| PPP2R1B | 8759 |
| CUL1 | 8725 |
| GAB2 | 8722 |
| HMOX1 | 8715 |
| MAP2K1 | 8704 |
| RHOU | 8693 |
| PSMD4 | 8670 |
| LCN2 | 8658 |
| PIM1 | 8647 |
| PSMC5 | 8646 |
| PTPN14 | 8577 |
| PTAFR | 8514 |
| IL11 | 8393 |
| TAB2 | 8201 |
| DUSP7 | 8185 |
| IL12A | 8182 |
| PSMD12 | 8163 |
| RPS6KA1 | 8159 |
| STAT3 | 8078 |
| CTF1 | 8054 |
| PSME3 | 8052 |
| PTPN2 | 8048 |
| FBXW11 | 7986 |
| LIFR | 7929 |
| RBX1 | 7850 |
| CNTF | 7828 |
| MTAP | 7801 |
| MCL1 | 7783 |
| IL20RB | 7608 |
| LIF | 7579 |
| CDKN1A | 7569 |
| INPP5D | 7467 |
| JUNB | 7447 |
| NFKB1 | 7409 |
| IL17RE | 7316 |
| MAP3K7 | 7172 |
| IL7 | 7119 |
| DUSP6 | 7113 |
| CHUK | 7086 |
| MAP2K3 | 7038 |
| CRLF1 | 7035 |
| MEF2A | 6959 |
| CXCL8 | 6916 |
| MAOA | 6912 |
| RAP1B | 6830 |
| SMARCA4 | 6773 |
| IRS1 | 6691 |
| IRF4 | 6647 |
| SEM1 | 6566 |
| FN1 | 6525 |
| IL4R | 6431 |
| PSMA3 | 6422 |
| GRB2 | 6346 |
| LYN | 6328 |
| RPS6KA3 | 6316 |
| TXLNA | 6268 |
| AKT1 | 6160 |
| JUN | 6103 |
| IKBKB | 6100 |
| PSMD8 | 6091 |
| PDCD4 | 6023 |
| RPS6KA5 | 5949 |
| PIK3CA | 5849 |
| VAMP7 | 5793 |
| RPS27A | 5776 |
| MAPK10 | 5681 |
| JAK2 | 5664 |
| PSMA5 | 5657 |
| RELA | 5468 |
| PIK3CB | 5379 |
| PSMD13 | 5353 |
| FSCN1 | 5006 |
| TAB3 | 4960 |
| PSMC2 | 4948 |
| STX1A | 4922 |
| MAP2K6 | 4868 |
| PSME1 | 4861 |
| PIK3R3 | 4734 |
| PTPN4 | 4643 |
| IRAK1 | 4593 |
| CDC42 | 4489 |
| FOXO3 | 4415 |
| GSTO1 | 4401 |
| MAPK14 | 4391 |
| PPP2R5D | 4385 |
| AGER | 4235 |
| SDC1 | 4201 |
| IFNLR1 | 4179 |
| TP53 | 4144 |
| IL18 | 4103 |
| PSMB3 | 3928 |
| IL6ST | 3837 |
| PELI2 | 3834 |
| FYN | 3783 |
| BCL2 | 3762 |
| ITGAX | 3756 |
| MYC | 3708 |
| PSMB2 | 3678 |
| UBE2N | 3604 |
| MAPK9 | 3449 |
| MMP3 | 3425 |
| PRKACA | 3407 |
| HAVCR2 | 3267 |
| TRAF6 | 3150 |
| IRAK4 | 3137 |
| STAT6 | 3128 |
| PSMC3 | 3070 |
| LGALS9 | 3034 |
| SIGIRR | 2961 |
| IL23A | 2869 |
| IL17RC | 2861 |
| BTRC | 2757 |
| PIK3R2 | 2728 |
| SOCS2 | 2710 |
| YES1 | 2690 |
| TNIP2 | 2640 |
| NFKB2 | 2634 |
| VRK3 | 2573 |
| ICAM1 | 2548 |
| BRWD1 | 2546 |
| POU2F1 | 2513 |
| OPRD1 | 2430 |
| RPS6KA2 | 2339 |
| PSMB4 | 2330 |
| NANOG | 2288 |
| BOLA2 | 2230 |
| HSP90AA1 | 2096 |
| PSMB1 | 2062 |
| SOS1 | 1928 |
| HNRNPDL | 1890 |
| LCP1 | 1834 |
| PSMA7 | 1820 |
| YWHAZ | 1810 |
| PTPN11 | 1770 |
| IL1R2 | 1751 |
| UBC | 1551 |
| PSMB5 | 1484 |
| STXBP2 | 1474 |
| MAPK8 | 1418 |
| IL22RA1 | 1251 |
| INPPL1 | 1197 |
| IL15 | 1148 |
| CCL22 | 1142 |
| SKP1 | 1117 |
| ZEB1 | 1087 |
| CRKL | 1039 |
| STX4 | 995 |
| CREB1 | 935 |
| PSMD11 | 879 |
| PSMB10 | 838 |
| IL12RB1 | 832 |
| IL1RL1 | 665 |
| IL16 | 518 |
| MAPK11 | 492 |
| IL17RA | 382 |
| NKIRAS1 | 298 |
| CCND1 | 277 |
| PSMA6 | 261 |
| IL27RA | 242 |
| STAT2 | 146 |
| CSF2RA | 94 |
Cell Cycle
| 139 | |
|---|---|
| set | Cell Cycle |
| setSize | 594 |
| pANOVA | 0.000791 |
| s.dist | 0.0812 |
| p.adjustANOVA | 0.0237 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| GINS1 | 14342 |
| SYNE1 | 14086 |
| CDC6 | 14067 |
| SEC13 | 14049 |
| CDK1 | 14027 |
| HMMR | 14001 |
| RMI2 | 13969 |
| LPIN3 | 13949 |
| LPIN2 | 13908 |
| NDC80 | 13840 |
| CABLES1 | 13825 |
| PSMF1 | 13810 |
| NUDC | 13808 |
| UBE2C | 13793 |
| UIMC1 | 13741 |
| LMNB1 | 13707 |
| NUP37 | 13706 |
| E2F1 | 13694 |
| TUBA1B | 13681 |
| CHMP4C | 13640 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| GINS1 | 14342 |
| SYNE1 | 14086 |
| CDC6 | 14067 |
| SEC13 | 14049 |
| CDK1 | 14027 |
| HMMR | 14001 |
| RMI2 | 13969 |
| LPIN3 | 13949 |
| LPIN2 | 13908 |
| NDC80 | 13840 |
| CABLES1 | 13825 |
| PSMF1 | 13810 |
| NUDC | 13808 |
| UBE2C | 13793 |
| UIMC1 | 13741 |
| LMNB1 | 13707 |
| NUP37 | 13706 |
| E2F1 | 13694 |
| TUBA1B | 13681 |
| CHMP4C | 13640 |
| KNL1 | 13621 |
| MAD2L1 | 13616 |
| VRK2 | 13580 |
| ANKLE2 | 13567 |
| LIN52 | 13530 |
| HAUS5 | 13521 |
| MYBL2 | 13519 |
| CENPK | 13518 |
| SPC24 | 13498 |
| RAN | 13497 |
| EP300 | 13485 |
| CLSPN | 13484 |
| NUF2 | 13470 |
| PSME4 | 13450 |
| NEDD1 | 13438 |
| MND1 | 13435 |
| BUB1B | 13431 |
| PSMD2 | 13423 |
| MCM5 | 13415 |
| HAUS4 | 13402 |
| CHEK2 | 13401 |
| TMPO | 13363 |
| PRIM1 | 13355 |
| RPA2 | 13354 |
| LEMD2 | 13339 |
| DHFR | 13334 |
| KPNB1 | 13324 |
| MIS12 | 13304 |
| POM121 | 13281 |
| POLE4 | 13279 |
| DSN1 | 13258 |
| GINS2 | 13245 |
| AURKB | 13190 |
| TOP2A | 13176 |
| TK1 | 13137 |
| TNPO1 | 13094 |
| CDC25C | 13084 |
| NUP210 | 13025 |
| MCM6 | 12996 |
| HJURP | 12958 |
| TUBA1C | 12940 |
| GINS3 | 12937 |
| TUBB4B | 12934 |
| MCM2 | 12926 |
| SPDL1 | 12856 |
| POLA2 | 12805 |
| RAD9A | 12760 |
| KNTC1 | 12758 |
| EXO1 | 12733 |
| CDCA8 | 12700 |
| CCNB2 | 12689 |
| POM121C | 12687 |
| MAPK3 | 12684 |
| MCM4 | 12667 |
| ESCO2 | 12665 |
| CKAP5 | 12651 |
| REC8 | 12639 |
| PRIM2 | 12596 |
| CCNA2 | 12587 |
| RNF8 | 12528 |
| GINS4 | 12516 |
| PSMD6 | 12502 |
| CLIP1 | 12494 |
| PCNA | 12452 |
| SKA2 | 12421 |
| E2F2 | 12251 |
| KIF2A | 12231 |
| PTTG1 | 12222 |
| PSMA2 | 12203 |
| ITGB3BP | 12199 |
| BRIP1 | 12189 |
| PCNT | 12160 |
| RPA3 | 12149 |
| SIRT2 | 12121 |
| CNTRL | 12110 |
| PPP2R5A | 12088 |
| RHNO1 | 12087 |
| RAD51 | 12057 |
| PSMA1 | 12052 |
| CSNK1D | 12038 |
| KIF23 | 12032 |
| ANAPC16 | 12018 |
| RCC2 | 12011 |
| CDC25B | 11958 |
| OPTN | 11914 |
| NDEL1 | 11904 |
| ANAPC7 | 11895 |
| ZWILCH | 11891 |
| CENPH | 11884 |
| LIG1 | 11811 |
| PPP2R2D | 11809 |
| CCP110 | 11807 |
| SSNA1 | 11800 |
| CDT1 | 11791 |
| PSMC1 | 11724 |
| DYRK1A | 11712 |
| TEN1 | 11707 |
| MCPH1 | 11698 |
| BARD1 | 11687 |
| POT1 | 11678 |
| PSMD3 | 11655 |
| SMC2 | 11646 |
| LPIN1 | 11643 |
| CDC23 | 11639 |
| PKMYT1 | 11586 |
| NUP107 | 11561 |
| PSME2 | 11555 |
| ANAPC10 | 11551 |
| NEK6 | 11540 |
| POLR2L | 11530 |
| DYNLL2 | 11507 |
| RAD51C | 11490 |
| GORASP2 | 11463 |
| CDK7 | 11458 |
| AJUBA | 11454 |
| BLM | 11423 |
| ZWINT | 11400 |
| NUP35 | 11387 |
| KIF2C | 11386 |
| PSMD14 | 11371 |
| CENPI | 11351 |
| POLR2K | 11350 |
| CDC25A | 11334 |
| RAB2A | 11326 |
| SKP2 | 11323 |
| KIF20A | 11285 |
| PSMD1 | 11280 |
| SPAST | 11237 |
| CENPQ | 11227 |
| CHMP6 | 11222 |
| RAD1 | 11219 |
| NCAPH | 11214 |
| GOLGA2 | 11209 |
| NEK9 | 11195 |
| CTDNEP1 | 11193 |
| TUBG1 | 11173 |
| POLR2F | 11158 |
| TERF1 | 11145 |
| NUP205 | 11144 |
| CDC7 | 11135 |
| PPP6C | 11074 |
| POLD1 | 11069 |
| NUP93 | 11067 |
| CEP192 | 11035 |
| SMC4 | 11020 |
| CETN2 | 11018 |
| CENPJ | 11011 |
| CEP290 | 10987 |
| GMNN | 10951 |
| TUBG2 | 10942 |
| CDK5RAP2 | 10940 |
| PPP2CA | 10917 |
| ACTR1A | 10903 |
| NCAPG | 10863 |
| TYMS | 10848 |
| PPP2R5B | 10834 |
| DIDO1 | 10824 |
| PPP2R2A | 10808 |
| GSK3B | 10767 |
| CENPC | 10756 |
| CDC20 | 10732 |
| NUMA1 | 10724 |
| UBA52 | 10707 |
| MAPK1 | 10705 |
| CDK4 | 10698 |
| CTC1 | 10690 |
| E2F6 | 10689 |
| BORA | 10684 |
| CSNK2A1 | 10637 |
| KMT5A | 10628 |
| PIAS4 | 10596 |
| CHMP4B | 10594 |
| CCNH | 10565 |
| RPA1 | 10563 |
| ENSA | 10545 |
| CENPE | 10538 |
| NUP188 | 10521 |
| RFC1 | 10506 |
| NOP10 | 10460 |
| ANAPC15 | 10442 |
| PSMB9 | 10430 |
| CDCA5 | 10400 |
| ATR | 10396 |
| PSMB6 | 10326 |
| PSMC6 | 10307 |
| CDKN2D | 10296 |
| PCBP4 | 10280 |
| MAX | 10232 |
| BRCA2 | 10219 |
| PSMC4 | 10196 |
| NEK2 | 10138 |
| NUP88 | 10134 |
| H2AFX | 10131 |
| RFC3 | 10111 |
| PPP2R1A | 10064 |
| RUVBL1 | 10058 |
| PLK4 | 10056 |
| NUP50 | 10047 |
| INCENP | 10005 |
| ESPL1 | 9994 |
| SGO2 | 9987 |
| CENPM | 9951 |
| POLR2E | 9916 |
| KIF18A | 9884 |
| PSMD9 | 9853 |
| SYNE2 | 9847 |
| BIRC5 | 9771 |
| PIF1 | 9764 |
| RBBP7 | 9712 |
| CEP78 | 9704 |
| B9D2 | 9695 |
| TUBB | 9694 |
| PSMD5 | 9676 |
| AKAP9 | 9671 |
| ORC3 | 9670 |
| BRCA1 | 9663 |
| CSNK2A2 | 9641 |
| PPP2CB | 9606 |
| CEP152 | 9577 |
| PLK1 | 9548 |
| MCM10 | 9536 |
| SEH1L | 9474 |
| SFI1 | 9420 |
| POLA1 | 9387 |
| PSMD7 | 9371 |
| HSP90AB1 | 9363 |
| PSMD10 | 9356 |
| POLD2 | 9350 |
| PSMB7 | 9253 |
| CEP76 | 9240 |
| TFDP2 | 9210 |
| CEP57 | 9181 |
| SKA1 | 9144 |
| FOXM1 | 9137 |
| NUP155 | 9102 |
| TP53BP1 | 9089 |
| TERF2IP | 9056 |
| MCM3 | 9054 |
| CDK6 | 9023 |
| UBB | 9013 |
| NHP2 | 9010 |
| GTSE1 | 8986 |
| CLASP2 | 8977 |
| CENPT | 8952 |
| VRK1 | 8944 |
| TUBA1A | 8932 |
| PSMA4 | 8902 |
| RFC4 | 8885 |
| RBL1 | 8842 |
| CEP41 | 8824 |
| SFN | 8812 |
| HAUS6 | 8791 |
| PPP2R1B | 8759 |
| MIS18A | 8742 |
| CUL1 | 8725 |
| PPP1R12B | 8721 |
| POLR2I | 8717 |
| MCM8 | 8710 |
| PSMD4 | 8670 |
| RTEL1 | 8668 |
| TERT | 8656 |
| PSMC5 | 8646 |
| CENPA | 8625 |
| RAD50 | 8623 |
| NBN | 8606 |
| AHCTF1 | 8598 |
| NINL | 8595 |
| ZW10 | 8564 |
| POLE2 | 8557 |
| TERF2 | 8496 |
| POLD3 | 8459 |
| MSH5 | 8386 |
| DCTN2 | 8375 |
| CSNK2B | 8368 |
| RAE1 | 8335 |
| RFC5 | 8324 |
| CHEK1 | 8292 |
| CENPU | 8282 |
| TINF2 | 8275 |
| MAD1L1 | 8264 |
| DYNC1LI2 | 8235 |
| PSMD12 | 8163 |
| CCND2 | 8117 |
| CENPW | 8100 |
| PSME3 | 8052 |
| CDKN2C | 8034 |
| TPX2 | 8033 |
| MZT2B | 8028 |
| PHF8 | 8025 |
| MAPRE1 | 8020 |
| STN1 | 8003 |
| FBXW11 | 7986 |
| CENPF | 7980 |
| TUBB2B | 7952 |
| NUP85 | 7946 |
| NUP98 | 7940 |
| HERC2 | 7888 |
| ANKRD28 | 7882 |
| NEK7 | 7858 |
| LMNA | 7854 |
| RBX1 | 7850 |
| ORC2 | 7840 |
| POLR2B | 7815 |
| CDK2 | 7809 |
| MRE11 | 7780 |
| PPP1CB | 7685 |
| TUBB8 | 7651 |
| DYNC1H1 | 7639 |
| POLR2H | 7590 |
| CDKN1A | 7569 |
| RNF168 | 7562 |
| CHTF18 | 7548 |
| SRC | 7516 |
| RRM2 | 7504 |
| ANAPC5 | 7485 |
| YWHAH | 7417 |
| MLH3 | 7414 |
| USO1 | 7413 |
| EMD | 7404 |
| RFC2 | 7371 |
| RAB1B | 7340 |
| HDAC8 | 7301 |
| MIS18BP1 | 7300 |
| RBBP8 | 7280 |
| NSD2 | 7232 |
| BANF1 | 7227 |
| POLR2C | 7212 |
| PPP1CC | 7149 |
| HUS1 | 7126 |
| PDS5A | 7116 |
| UBE2E1 | 7102 |
| CDKN2A | 7056 |
| STAG1 | 7037 |
| MDC1 | 6989 |
| NCAPD3 | 6972 |
| RAB1A | 6957 |
| RBBP4 | 6938 |
| DAXX | 6929 |
| POLD4 | 6907 |
| RMI1 | 6903 |
| FBXO5 | 6788 |
| UBE2D1 | 6734 |
| NSL1 | 6722 |
| FKBPL | 6720 |
| HAUS8 | 6695 |
| PPP2R3B | 6689 |
| BLZF1 | 6684 |
| LBR | 6666 |
| PPME1 | 6623 |
| RANGAP1 | 6615 |
| E2F4 | 6609 |
| NIPBL | 6603 |
| SEM1 | 6566 |
| HAUS3 | 6563 |
| HSPA2 | 6538 |
| BUB1 | 6536 |
| DNA2 | 6486 |
| UBE2V2 | 6467 |
| TUBGCP5 | 6445 |
| CEP164 | 6425 |
| PSMA3 | 6422 |
| NUP54 | 6371 |
| SUMO1 | 6365 |
| PTK6 | 6358 |
| LYN | 6328 |
| GAR1 | 6286 |
| CSNK1E | 6238 |
| SUN2 | 6171 |
| AKT1 | 6160 |
| PDS5B | 6136 |
| HAUS7 | 6092 |
| PSMD8 | 6091 |
| DBF4 | 6080 |
| OIP5 | 6044 |
| CC2D1B | 6039 |
| NCAPD2 | 5978 |
| TAOK1 | 5951 |
| ACD | 5857 |
| TUBGCP3 | 5843 |
| WRN | 5841 |
| MZT1 | 5824 |
| DYNC1I2 | 5783 |
| RPS27A | 5776 |
| BABAM1 | 5721 |
| PHF20 | 5717 |
| AAAS | 5701 |
| JAK2 | 5664 |
| PSMA5 | 5657 |
| MASTL | 5640 |
| CCND3 | 5565 |
| HDAC1 | 5563 |
| STAG3 | 5548 |
| STAG2 | 5443 |
| TUBGCP4 | 5424 |
| NUP43 | 5410 |
| ODF2 | 5391 |
| NCAPH2 | 5381 |
| TFDP1 | 5361 |
| PSMD13 | 5353 |
| MDM4 | 5318 |
| CCNE1 | 5315 |
| PPP2R5C | 5293 |
| CKS1B | 5274 |
| WEE1 | 5244 |
| DYNC1LI1 | 5237 |
| TUBB1 | 5236 |
| NUP153 | 5230 |
| POLR2A | 5219 |
| CHMP7 | 5197 |
| LCMT1 | 5160 |
| PMF1 | 5043 |
| RUVBL2 | 5012 |
| PSMC2 | 4948 |
| ATRX | 4939 |
| TOP3A | 4927 |
| PCM1 | 4925 |
| SMC3 | 4924 |
| MCM7 | 4863 |
| PSME1 | 4861 |
| DYNLL1 | 4853 |
| PRKCA | 4709 |
| ORC5 | 4688 |
| POLR2D | 4674 |
| RAB8A | 4658 |
| NUP58 | 4603 |
| VPS4A | 4592 |
| BRCC3 | 4560 |
| RCC1 | 4473 |
| RSF1 | 4426 |
| DSCC1 | 4396 |
| PPP2R5D | 4385 |
| CENPN | 4377 |
| ORC1 | 4368 |
| LIN54 | 4306 |
| WRAP53 | 4218 |
| NPM1 | 4183 |
| LIN9 | 4167 |
| CCNE2 | 4152 |
| RFWD2 | 4150 |
| TP53 | 4144 |
| IST1 | 4111 |
| SET | 4107 |
| YWHAB | 4062 |
| AKT2 | 3993 |
| POLE | 3985 |
| NUP214 | 3957 |
| ABL1 | 3944 |
| PSMB3 | 3928 |
| SGO1 | 3925 |
| POLR2G | 3910 |
| ANAPC1 | 3900 |
| UBE2S | 3839 |
| TUBGCP6 | 3832 |
| XPO1 | 3824 |
| ORC6 | 3780 |
| GORASP1 | 3727 |
| MYC | 3708 |
| PSMB2 | 3678 |
| ORC4 | 3669 |
| ATRIP | 3626 |
| UBE2N | 3604 |
| CEP250 | 3590 |
| NDE1 | 3555 |
| CDC45 | 3490 |
| SYCE2 | 3437 |
| PRKACA | 3407 |
| CDKN2B | 3352 |
| ANAPC2 | 3349 |
| PSMC3IP | 3347 |
| DCTN1 | 3338 |
| RBL2 | 3324 |
| TUBGCP2 | 3172 |
| ANAPC11 | 3134 |
| KAT5 | 3115 |
| CDC27 | 3103 |
| HAUS1 | 3101 |
| CLASP1 | 3071 |
| PSMC3 | 3070 |
| FBXL18 | 3067 |
| NDC1 | 3023 |
| CEP135 | 2992 |
| ATM | 2965 |
| DCTN3 | 2887 |
| BTRC | 2757 |
| CENPP | 2725 |
| MLH1 | 2724 |
| NUP133 | 2708 |
| UBE2I | 2653 |
| ESCO1 | 2579 |
| TUBA8 | 2575 |
| TUBB2A | 2568 |
| DKC1 | 2517 |
| CHMP3 | 2417 |
| AURKA | 2412 |
| SHQ1 | 2362 |
| PSMB4 | 2330 |
| SMARCA5 | 2323 |
| CDC16 | 2309 |
| POLE3 | 2308 |
| LIN37 | 2294 |
| BUB3 | 2290 |
| TUBB6 | 2268 |
| CEP131 | 2251 |
| CHMP2A | 2222 |
| SDCCAG8 | 2210 |
| PPP1R12A | 2182 |
| E2F5 | 2102 |
| HSP90AA1 | 2096 |
| YWHAG | 2081 |
| PSMB1 | 2062 |
| CEP70 | 1965 |
| CEP72 | 1949 |
| MDM2 | 1942 |
| LEMD3 | 1868 |
| PSMA7 | 1820 |
| YWHAZ | 1810 |
| CHMP2B | 1797 |
| CHMP4A | 1779 |
| HAUS2 | 1773 |
| MAU2 | 1767 |
| RAD17 | 1689 |
| CCNB1 | 1641 |
| CDK11B | 1640 |
| CDKN1B | 1590 |
| SMC1A | 1560 |
| NME7 | 1556 |
| UBC | 1551 |
| NCAPG2 | 1539 |
| CENPL | 1495 |
| PSMB5 | 1484 |
| TUBA4A | 1335 |
| PPP6R3 | 1271 |
| ARPP19 | 1262 |
| POLR2J | 1234 |
| RAD21 | 1178 |
| SKP1 | 1117 |
| TPR | 1105 |
| YWHAQ | 1061 |
| CDK11A | 1049 |
| CNEP1R1 | 972 |
| RB1 | 925 |
| PSMD11 | 879 |
| E2F3 | 876 |
| TUBB3 | 858 |
| CEP63 | 854 |
| PSMB10 | 838 |
| CENPO | 820 |
| SUN1 | 791 |
| FEN1 | 721 |
| PHLDA1 | 720 |
| NUP160 | 683 |
| ZNF385A | 672 |
| WAPL | 620 |
| NUP62 | 618 |
| ANAPC4 | 595 |
| MZT2A | 582 |
| ALMS1 | 578 |
| PPP2R5E | 554 |
| TOPBP1 | 544 |
| CHTF8 | 440 |
| MNAT1 | 420 |
| CDC26 | 402 |
| FZR1 | 397 |
| RPS27 | 312 |
| CCND1 | 277 |
| PSMA6 | 261 |
| YWHAE | 253 |
| CDC14A | 249 |
| PAFAH1B1 | 237 |
| ERCC6L | 86 |
| OFD1 | 83 |
| EML4 | 66 |
| RAD9B | 50 |
| RANBP2 | 9 |
RHO GTPases Activate Formins
| 864 | |
|---|---|
| set | RHO GTPases Activate Formins |
| setSize | 116 |
| pANOVA | 0.00107 |
| s.dist | 0.176 |
| p.adjustANOVA | 0.0313 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| DVL3 | 14293 |
| ACTG1 | 14090 |
| SEC13 | 14049 |
| RHOC | 13943 |
| NDC80 | 13840 |
| NUDC | 13808 |
| NUP37 | 13706 |
| KNL1 | 13621 |
| MAD2L1 | 13616 |
| CENPK | 13518 |
| SPC24 | 13498 |
| NUF2 | 13470 |
| BUB1B | 13431 |
| MIS12 | 13304 |
| DSN1 | 13258 |
| AURKB | 13190 |
| PFN2 | 13179 |
| PFN1 | 13146 |
| SPDL1 | 12856 |
| KNTC1 | 12758 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| DVL3 | 14293 |
| ACTG1 | 14090 |
| SEC13 | 14049 |
| RHOC | 13943 |
| NDC80 | 13840 |
| NUDC | 13808 |
| NUP37 | 13706 |
| KNL1 | 13621 |
| MAD2L1 | 13616 |
| CENPK | 13518 |
| SPC24 | 13498 |
| NUF2 | 13470 |
| BUB1B | 13431 |
| MIS12 | 13304 |
| DSN1 | 13258 |
| AURKB | 13190 |
| PFN2 | 13179 |
| PFN1 | 13146 |
| SPDL1 | 12856 |
| KNTC1 | 12758 |
| CDCA8 | 12700 |
| CKAP5 | 12651 |
| CLIP1 | 12494 |
| SKA2 | 12421 |
| KIF2A | 12231 |
| DIAPH1 | 12211 |
| ITGB3BP | 12199 |
| PPP2R5A | 12088 |
| RCC2 | 12011 |
| NDEL1 | 11904 |
| ZWILCH | 11891 |
| CENPH | 11884 |
| NUP107 | 11561 |
| RHOB | 11537 |
| DYNLL2 | 11507 |
| ZWINT | 11400 |
| KIF2C | 11386 |
| CENPI | 11351 |
| CENPQ | 11227 |
| RHOA | 11182 |
| PPP2CA | 10917 |
| PPP2R5B | 10834 |
| CENPC | 10756 |
| CDC20 | 10732 |
| ACTB | 10683 |
| CENPE | 10538 |
| PPP2R1A | 10064 |
| INCENP | 10005 |
| SGO2 | 9987 |
| CENPM | 9951 |
| KIF18A | 9884 |
| BIRC5 | 9771 |
| B9D2 | 9695 |
| PPP2CB | 9606 |
| PLK1 | 9548 |
| DIAPH3 | 9508 |
| SEH1L | 9474 |
| DAAM1 | 9439 |
| SCAI | 9277 |
| SKA1 | 9144 |
| CLASP2 | 8977 |
| CENPT | 8952 |
| ITGB1 | 8760 |
| PPP2R1B | 8759 |
| FMNL2 | 8666 |
| CENPA | 8625 |
| AHCTF1 | 8598 |
| ZW10 | 8564 |
| CENPU | 8282 |
| MAD1L1 | 8264 |
| DYNC1LI2 | 8235 |
| MAPRE1 | 8020 |
| CENPF | 7980 |
| NUP85 | 7946 |
| NUP98 | 7940 |
| DYNC1H1 | 7639 |
| SRC | 7516 |
| PPP1CC | 7149 |
| NSL1 | 6722 |
| RANGAP1 | 6615 |
| BUB1 | 6536 |
| SRF | 6447 |
| TAOK1 | 5951 |
| DYNC1I2 | 5783 |
| NUP43 | 5410 |
| PPP2R5C | 5293 |
| DYNC1LI1 | 5237 |
| PMF1 | 5043 |
| FMNL1 | 4980 |
| DYNLL1 | 4853 |
| DIAPH2 | 4808 |
| EVL | 4757 |
| DVL1 | 4696 |
| CDC42 | 4489 |
| PPP2R5D | 4385 |
| CENPN | 4377 |
| SGO1 | 3925 |
| XPO1 | 3824 |
| SRGAP2 | 3627 |
| NDE1 | 3555 |
| CLASP1 | 3071 |
| CENPP | 2725 |
| NUP133 | 2708 |
| RHOD | 2596 |
| BUB3 | 2290 |
| FMNL3 | 2271 |
| DVL2 | 1843 |
| CENPL | 1495 |
| CENPO | 820 |
| NUP160 | 683 |
| PPP2R5E | 554 |
| RPS27 | 312 |
| PAFAH1B1 | 237 |
| RAC1 | 95 |
| ERCC6L | 86 |
| RANBP2 | 9 |
Inactivation, recovery and regulation of the phototransduction cascade
| 506 | |
|---|---|
| set | Inactivation, recovery and regulation of the phototransduction cascade |
| setSize | 20 |
| pANOVA | 0.00111 |
| s.dist | -0.421 |
| p.adjustANOVA | 0.0317 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| PDE6G | 134 |
| PDE6A | 354 |
| SAG | 394 |
| GUCA1B | 786 |
| CALM1 | 1340 |
| GNB5 | 1388 |
| CAMKMT | 1898 |
| CNGA1 | 1946 |
| NMT2 | 3710 |
| CNGB1 | 3798 |
| METAP2 | 3812 |
| NMT1 | 4289 |
| PRKCA | 4709 |
| FNTB | 5296 |
| RGS9 | 5517 |
| GNB1 | 6796 |
| GRK4 | 7256 |
| METAP1 | 7421 |
| RGS9BP | 10201 |
| FNTA | 13142 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| PDE6G | 134 |
| PDE6A | 354 |
| SAG | 394 |
| GUCA1B | 786 |
| CALM1 | 1340 |
| GNB5 | 1388 |
| CAMKMT | 1898 |
| CNGA1 | 1946 |
| NMT2 | 3710 |
| CNGB1 | 3798 |
| METAP2 | 3812 |
| NMT1 | 4289 |
| PRKCA | 4709 |
| FNTB | 5296 |
| RGS9 | 5517 |
| GNB1 | 6796 |
| GRK4 | 7256 |
| METAP1 | 7421 |
| RGS9BP | 10201 |
| FNTA | 13142 |
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
| 57 | |
|---|---|
| set | Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal |
| setSize | 90 |
| pANOVA | 0.00124 |
| s.dist | 0.197 |
| p.adjustANOVA | 0.0341 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SEC13 | 14049 |
| NDC80 | 13840 |
| NUDC | 13808 |
| NUP37 | 13706 |
| KNL1 | 13621 |
| MAD2L1 | 13616 |
| CENPK | 13518 |
| SPC24 | 13498 |
| NUF2 | 13470 |
| BUB1B | 13431 |
| MIS12 | 13304 |
| DSN1 | 13258 |
| AURKB | 13190 |
| SPDL1 | 12856 |
| KNTC1 | 12758 |
| CDCA8 | 12700 |
| CKAP5 | 12651 |
| CLIP1 | 12494 |
| SKA2 | 12421 |
| KIF2A | 12231 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SEC13 | 14049 |
| NDC80 | 13840 |
| NUDC | 13808 |
| NUP37 | 13706 |
| KNL1 | 13621 |
| MAD2L1 | 13616 |
| CENPK | 13518 |
| SPC24 | 13498 |
| NUF2 | 13470 |
| BUB1B | 13431 |
| MIS12 | 13304 |
| DSN1 | 13258 |
| AURKB | 13190 |
| SPDL1 | 12856 |
| KNTC1 | 12758 |
| CDCA8 | 12700 |
| CKAP5 | 12651 |
| CLIP1 | 12494 |
| SKA2 | 12421 |
| KIF2A | 12231 |
| ITGB3BP | 12199 |
| PPP2R5A | 12088 |
| RCC2 | 12011 |
| NDEL1 | 11904 |
| ZWILCH | 11891 |
| CENPH | 11884 |
| NUP107 | 11561 |
| DYNLL2 | 11507 |
| ZWINT | 11400 |
| KIF2C | 11386 |
| CENPI | 11351 |
| CENPQ | 11227 |
| PPP2CA | 10917 |
| PPP2R5B | 10834 |
| CENPC | 10756 |
| CDC20 | 10732 |
| CENPE | 10538 |
| PPP2R1A | 10064 |
| INCENP | 10005 |
| SGO2 | 9987 |
| CENPM | 9951 |
| KIF18A | 9884 |
| BIRC5 | 9771 |
| B9D2 | 9695 |
| PPP2CB | 9606 |
| PLK1 | 9548 |
| SEH1L | 9474 |
| SKA1 | 9144 |
| CLASP2 | 8977 |
| CENPT | 8952 |
| PPP2R1B | 8759 |
| CENPA | 8625 |
| AHCTF1 | 8598 |
| ZW10 | 8564 |
| CENPU | 8282 |
| MAD1L1 | 8264 |
| DYNC1LI2 | 8235 |
| MAPRE1 | 8020 |
| CENPF | 7980 |
| NUP85 | 7946 |
| NUP98 | 7940 |
| DYNC1H1 | 7639 |
| PPP1CC | 7149 |
| NSL1 | 6722 |
| RANGAP1 | 6615 |
| BUB1 | 6536 |
| TAOK1 | 5951 |
| DYNC1I2 | 5783 |
| NUP43 | 5410 |
| PPP2R5C | 5293 |
| DYNC1LI1 | 5237 |
| PMF1 | 5043 |
| DYNLL1 | 4853 |
| PPP2R5D | 4385 |
| CENPN | 4377 |
| SGO1 | 3925 |
| XPO1 | 3824 |
| NDE1 | 3555 |
| CLASP1 | 3071 |
| CENPP | 2725 |
| NUP133 | 2708 |
| BUB3 | 2290 |
| CENPL | 1495 |
| CENPO | 820 |
| NUP160 | 683 |
| PPP2R5E | 554 |
| RPS27 | 312 |
| PAFAH1B1 | 237 |
| ERCC6L | 86 |
| RANBP2 | 9 |
Amplification of signal from the kinetochores
| 58 | |
|---|---|
| set | Amplification of signal from the kinetochores |
| setSize | 90 |
| pANOVA | 0.00124 |
| s.dist | 0.197 |
| p.adjustANOVA | 0.0341 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SEC13 | 14049 |
| NDC80 | 13840 |
| NUDC | 13808 |
| NUP37 | 13706 |
| KNL1 | 13621 |
| MAD2L1 | 13616 |
| CENPK | 13518 |
| SPC24 | 13498 |
| NUF2 | 13470 |
| BUB1B | 13431 |
| MIS12 | 13304 |
| DSN1 | 13258 |
| AURKB | 13190 |
| SPDL1 | 12856 |
| KNTC1 | 12758 |
| CDCA8 | 12700 |
| CKAP5 | 12651 |
| CLIP1 | 12494 |
| SKA2 | 12421 |
| KIF2A | 12231 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SEC13 | 14049 |
| NDC80 | 13840 |
| NUDC | 13808 |
| NUP37 | 13706 |
| KNL1 | 13621 |
| MAD2L1 | 13616 |
| CENPK | 13518 |
| SPC24 | 13498 |
| NUF2 | 13470 |
| BUB1B | 13431 |
| MIS12 | 13304 |
| DSN1 | 13258 |
| AURKB | 13190 |
| SPDL1 | 12856 |
| KNTC1 | 12758 |
| CDCA8 | 12700 |
| CKAP5 | 12651 |
| CLIP1 | 12494 |
| SKA2 | 12421 |
| KIF2A | 12231 |
| ITGB3BP | 12199 |
| PPP2R5A | 12088 |
| RCC2 | 12011 |
| NDEL1 | 11904 |
| ZWILCH | 11891 |
| CENPH | 11884 |
| NUP107 | 11561 |
| DYNLL2 | 11507 |
| ZWINT | 11400 |
| KIF2C | 11386 |
| CENPI | 11351 |
| CENPQ | 11227 |
| PPP2CA | 10917 |
| PPP2R5B | 10834 |
| CENPC | 10756 |
| CDC20 | 10732 |
| CENPE | 10538 |
| PPP2R1A | 10064 |
| INCENP | 10005 |
| SGO2 | 9987 |
| CENPM | 9951 |
| KIF18A | 9884 |
| BIRC5 | 9771 |
| B9D2 | 9695 |
| PPP2CB | 9606 |
| PLK1 | 9548 |
| SEH1L | 9474 |
| SKA1 | 9144 |
| CLASP2 | 8977 |
| CENPT | 8952 |
| PPP2R1B | 8759 |
| CENPA | 8625 |
| AHCTF1 | 8598 |
| ZW10 | 8564 |
| CENPU | 8282 |
| MAD1L1 | 8264 |
| DYNC1LI2 | 8235 |
| MAPRE1 | 8020 |
| CENPF | 7980 |
| NUP85 | 7946 |
| NUP98 | 7940 |
| DYNC1H1 | 7639 |
| PPP1CC | 7149 |
| NSL1 | 6722 |
| RANGAP1 | 6615 |
| BUB1 | 6536 |
| TAOK1 | 5951 |
| DYNC1I2 | 5783 |
| NUP43 | 5410 |
| PPP2R5C | 5293 |
| DYNC1LI1 | 5237 |
| PMF1 | 5043 |
| DYNLL1 | 4853 |
| PPP2R5D | 4385 |
| CENPN | 4377 |
| SGO1 | 3925 |
| XPO1 | 3824 |
| NDE1 | 3555 |
| CLASP1 | 3071 |
| CENPP | 2725 |
| NUP133 | 2708 |
| BUB3 | 2290 |
| CENPL | 1495 |
| CENPO | 820 |
| NUP160 | 683 |
| PPP2R5E | 554 |
| RPS27 | 312 |
| PAFAH1B1 | 237 |
| ERCC6L | 86 |
| RANBP2 | 9 |
Here is the session info with all the versions of packages used.
sessionInfo()## R version 4.1.2 (2021-11-01)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 20.04.3 LTS
##
## Matrix products: default
## BLAS: /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.9.0
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.9.0
##
## locale:
## [1] LC_CTYPE=en_AU.UTF-8 LC_NUMERIC=C
## [3] LC_TIME=en_AU.UTF-8 LC_COLLATE=en_AU.UTF-8
## [5] LC_MONETARY=en_AU.UTF-8 LC_MESSAGES=en_AU.UTF-8
## [7] LC_PAPER=en_AU.UTF-8 LC_NAME=C
## [9] LC_ADDRESS=C LC_TELEPHONE=C
## [11] LC_MEASUREMENT=en_AU.UTF-8 LC_IDENTIFICATION=C
##
## attached base packages:
## [1] parallel stats4 stats graphics grDevices utils datasets
## [8] methods base
##
## other attached packages:
## [1] pkgload_1.2.4 GGally_2.1.2
## [3] ggplot2_3.3.5 reshape2_1.4.4
## [5] beeswarm_0.4.0 gplots_3.1.1
## [7] gtools_3.9.2 tibble_3.1.6
## [9] dplyr_1.0.7 echarts4r_0.4.3
## [11] eulerr_6.1.1 kableExtra_1.3.4
## [13] mitch_1.4.1 clusterProfiler_4.0.5
## [15] DESeq2_1.32.0 SummarizedExperiment_1.22.0
## [17] Biobase_2.52.0 MatrixGenerics_1.4.3
## [19] matrixStats_0.61.0 GenomicRanges_1.44.0
## [21] GenomeInfoDb_1.28.4 IRanges_2.26.0
## [23] S4Vectors_0.30.2 BiocGenerics_0.38.0
## [25] getDEE2_1.2.0
##
## loaded via a namespace (and not attached):
## [1] shadowtext_0.1.1 fastmatch_1.1-3 systemfonts_1.0.3
## [4] plyr_1.8.6 igraph_1.2.11 lazyeval_0.2.2
## [7] polylabelr_0.2.0 splines_4.1.2 BiocParallel_1.26.2
## [10] digest_0.6.29 yulab.utils_0.0.4 htmltools_0.5.2
## [13] GOSemSim_2.18.1 viridis_0.6.2 GO.db_3.13.0
## [16] fansi_1.0.0 magrittr_2.0.1 memoise_2.0.1
## [19] Biostrings_2.60.2 annotate_1.70.0 graphlayouts_0.8.0
## [22] svglite_2.0.0 enrichplot_1.12.3 colorspace_2.0-2
## [25] rvest_1.0.2 blob_1.2.2 ggrepel_0.9.1
## [28] xfun_0.29 tcltk_4.1.2 crayon_1.4.2
## [31] RCurl_1.98-1.5 jsonlite_1.7.2 scatterpie_0.1.7
## [34] genefilter_1.74.1 survival_3.2-13 ape_5.6-1
## [37] glue_1.6.0 polyclip_1.10-0 gtable_0.3.0
## [40] zlibbioc_1.38.0 XVector_0.32.0 webshot_0.5.2
## [43] htm2txt_2.1.1 DelayedArray_0.18.0 scales_1.1.1
## [46] DOSE_3.18.3 DBI_1.1.2 Rcpp_1.0.7
## [49] viridisLite_0.4.0 xtable_1.8-4 gridGraphics_0.5-1
## [52] tidytree_0.3.7 bit_4.0.4 htmlwidgets_1.5.4
## [55] httr_1.4.2 fgsea_1.18.0 RColorBrewer_1.1-2
## [58] ellipsis_0.3.2 pkgconfig_2.0.3 reshape_0.8.8
## [61] XML_3.99-0.8 farver_2.1.0 sass_0.4.0
## [64] locfit_1.5-9.4 utf8_1.2.2 labeling_0.4.2
## [67] ggplotify_0.1.0 tidyselect_1.1.1 rlang_0.4.12
## [70] later_1.3.0 AnnotationDbi_1.54.1 munsell_0.5.0
## [73] tools_4.1.2 cachem_1.0.6 downloader_0.4
## [76] generics_0.1.1 RSQLite_2.2.9 evaluate_0.14
## [79] stringr_1.4.0 fastmap_1.1.0 yaml_2.2.1
## [82] ggtree_3.0.4 knitr_1.37 bit64_4.0.5
## [85] tidygraph_1.2.0 caTools_1.18.2 purrr_0.3.4
## [88] KEGGREST_1.32.0 ggraph_2.0.5 nlme_3.1-153
## [91] mime_0.12 aplot_0.1.2 xml2_1.3.3
## [94] DO.db_2.9 rstudioapi_0.13 compiler_4.1.2
## [97] png_0.1-7 testthat_3.1.1 treeio_1.16.2
## [100] tweenr_1.0.2 geneplotter_1.70.0 bslib_0.3.1
## [103] stringi_1.7.6 highr_0.9 desc_1.4.0
## [106] lattice_0.20-45 Matrix_1.4-0 vctrs_0.3.8
## [109] pillar_1.6.4 lifecycle_1.0.1 jquerylib_0.1.4
## [112] data.table_1.14.2 cowplot_1.1.1 bitops_1.0-7
## [115] httpuv_1.6.5 patchwork_1.1.1 qvalue_2.24.0
## [118] R6_2.5.1 promises_1.2.0.1 KernSmooth_2.23-20
## [121] gridExtra_2.3 MASS_7.3-54 assertthat_0.2.1
## [124] rprojroot_2.0.2 withr_2.4.3 GenomeInfoDbData_1.2.6
## [127] grid_4.1.2 ggfun_0.0.4 tidyr_1.1.4
## [130] rmarkdown_2.11 ggforce_0.3.3 shiny_1.7.1END of report