Mitch Report

date generated: 2022-01-20

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

##                 x       abs
## A1BG    4.1644895 4.1644895
## A1CF    2.8783151 2.8783151
## A2M     0.3828562 0.3828562
## A4GALT  1.0571952 1.0571952
## AAAS    1.0071471 1.0071471
## AACS   -2.0539621 2.0539621

Here are some metrics about the input data profile:

Profile metrics

	Profile metrics
num_genes_in_profile	14533
duplicated_genes_present	0
num_profile_genes_in_sets	7596
num_profile_genes_not_in_sets	6937
profile_pearson_correl	-0.19928
profile_spearman_correl	-0.03984

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt

Gene sets metrics

	Gene sets metrics
num_genesets	2512
num_genesets_excluded	1135
num_genesets_included	1377

Gene sets by quadrant

Number of significant gene sets (FDR<0.05)= 409

Interactive enrichment scatterplot

All sets with FDR<0.05. Try hovering over the points.

Top N sets irrespective of FDR. Try hovering over the points.

A heatmap of S values for top results

A plot of effect size versus significance

Significance is the -log2(p.adjustMANOVA) and effect size is the s.dist which is the hypotenuse of the s scores.

Results table

Top N= 50 gene sets

set	setSize	pMANOVA	p.adjustMANOVA	s.dist	s.x	s.abs	p.x	p.abs
Cellular responses to stimuli	641	2.71e-23	3.73e-20	0.241	-0.2220	0.09200	1.36e-21	7.93e-05
Asparagine N-linked glycosylation	252	2.39e-22	1.64e-19	0.372	-0.3060	0.21200	6.70e-17	7.65e-09
Cellular responses to stress	633	6.23e-22	2.86e-19	0.235	-0.2170	0.08980	2.20e-20	1.29e-04
Cholesterol biosynthesis	24	2.36e-19	8.13e-17	1.070	0.8430	0.65900	8.63e-13	2.32e-08
Infectious disease	637	9.29e-18	2.56e-15	0.208	-0.2060	0.02470	1.06e-18	2.92e-01
Signal Transduction	1748	2.01e-17	4.62e-15	0.131	-0.1060	0.07770	6.08e-13	1.28e-07
Unfolded Protein Response (UPR)	89	3.68e-17	7.23e-15	0.544	-0.3930	0.37600	1.43e-10	9.26e-10
SRP-dependent cotranslational protein targeting to membrane	109	1.60e-16	2.75e-14	0.473	-0.4730	0.02290	1.48e-17	6.80e-01
Metabolism of proteins	1550	1.40e-15	2.15e-13	0.130	-0.1180	0.05560	3.25e-14	3.40e-04
Axon guidance	424	3.06e-15	3.88e-13	0.233	-0.2320	0.00935	2.94e-16	7.42e-01
Immune System	1374	3.10e-15	3.88e-13	0.136	-0.1060	0.08550	8.91e-11	1.75e-07
IRE1alpha activates chaperones	50	6.59e-15	7.56e-13	0.673	-0.4890	0.46300	2.24e-09	1.48e-08
Innate Immune System	740	2.59e-14	2.75e-12	0.176	-0.1250	0.12300	9.58e-09	1.49e-08
Cellular response to starvation	149	1.93e-13	1.90e-11	0.363	-0.3630	0.00455	2.02e-14	9.24e-01
XBP1(S) activates chaperone genes	48	3.69e-13	3.38e-11	0.643	-0.4680	0.44200	2.02e-08	1.21e-07
L13a-mediated translational silencing of Ceruloplasmin expression	108	5.33e-13	4.58e-11	0.415	-0.4040	-0.09450	4.15e-13	9.02e-02
Nervous system development	444	5.72e-13	4.63e-11	0.209	-0.2090	0.01660	6.25e-14	5.51e-01
GTP hydrolysis and joining of the 60S ribosomal subunit	109	9.36e-13	7.16e-11	0.409	-0.3990	-0.08810	5.93e-13	1.13e-01
Formation of a pool of free 40S subunits	98	2.32e-12	1.61e-10	0.422	-0.3970	-0.14400	1.12e-11	1.39e-02
Cap-dependent Translation Initiation	116	2.46e-12	1.61e-10	0.390	-0.3800	-0.08610	1.61e-12	1.10e-01
Eukaryotic Translation Initiation	116	2.46e-12	1.61e-10	0.390	-0.3800	-0.08610	1.61e-12	1.10e-01
Disease	1247	2.59e-12	1.62e-10	0.127	-0.1140	0.05500	2.40e-11	1.30e-03
DNA strand elongation	32	3.14e-12	1.88e-10	0.729	0.6020	0.41100	3.66e-09	5.82e-05
Complement cascade	35	3.47e-12	1.94e-10	0.695	0.4980	0.48500	3.48e-07	6.84e-07
Developmental Biology	677	3.52e-12	1.94e-10	0.166	-0.1630	0.02810	6.00e-13	2.17e-01
Translation	270	5.70e-12	3.02e-10	0.254	-0.2530	-0.02240	9.51e-13	5.29e-01
Eukaryotic Translation Elongation	91	6.39e-12	3.17e-10	0.430	-0.4070	-0.14000	2.06e-11	2.12e-02
Regulation of expression of SLITs and ROBOs	157	6.44e-12	3.17e-10	0.330	-0.3250	-0.05560	2.15e-12	2.30e-01
Signaling by ROBO receptors	193	8.70e-12	4.13e-10	0.296	-0.2930	-0.04670	2.58e-12	2.64e-01
Diseases of signal transduction by growth factor receptors and second messengers	361	1.36e-11	6.24e-10	0.219	-0.2140	0.04980	3.78e-12	1.05e-01
Response of EIF2AK4 (GCN2) to amino acid deficiency	98	1.42e-11	6.29e-10	0.410	-0.4000	-0.08680	7.59e-12	1.38e-01
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	34	1.79e-11	7.72e-10	0.710	-0.5740	0.41800	7.03e-09	2.46e-05
Viral mRNA Translation	86	2.30e-11	9.61e-10	0.431	-0.4100	-0.13500	5.18e-11	3.09e-02
Post-translational protein modification	1138	2.54e-11	1.03e-09	0.127	-0.0967	0.08220	5.82e-08	4.03e-06
Peptide chain elongation	86	2.62e-11	1.03e-09	0.430	-0.4050	-0.14300	8.24e-11	2.19e-02
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	91	2.70e-11	1.03e-09	0.419	-0.4060	-0.10500	2.32e-11	8.42e-02
Regulation of Complement cascade	30	3.18e-11	1.18e-09	0.719	0.5550	0.45700	1.43e-07	1.50e-05
rRNA processing in the nucleus and cytosol	184	4.11e-11	1.49e-09	0.292	-0.2780	-0.08940	7.82e-11	3.68e-02
Metabolism of RNA	658	5.13e-11	1.81e-09	0.158	-0.1560	-0.02050	1.16e-11	3.74e-01
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	111	5.72e-11	1.92e-09	0.374	-0.3640	-0.08700	3.73e-11	1.14e-01
Nonsense-Mediated Decay (NMD)	111	5.72e-11	1.92e-09	0.374	-0.3640	-0.08700	3.73e-11	1.14e-01
Major pathway of rRNA processing in the nucleolus and cytosol	174	1.64e-10	5.38e-09	0.292	-0.2800	-0.08210	1.91e-10	6.24e-02
SARS-CoV Infections	144	1.93e-10	6.17e-09	0.327	-0.3120	0.09630	1.05e-10	4.64e-02
Selenocysteine synthesis	89	2.72e-10	8.30e-09	0.402	-0.3750	-0.14400	1.00e-09	1.89e-02
Eukaryotic Translation Termination	89	2.77e-10	8.30e-09	0.402	-0.3870	-0.11000	2.80e-10	7.25e-02
Signaling by Receptor Tyrosine Kinases	405	2.77e-10	8.30e-09	0.196	-0.1790	0.07950	7.81e-10	6.32e-03
Influenza Infection	151	3.58e-10	1.05e-08	0.310	-0.3090	-0.02920	6.29e-11	5.37e-01
Transport of small molecules	535	5.27e-10	1.51e-08	0.169	-0.1280	0.11100	4.55e-07	1.35e-05
Transport to the Golgi and subsequent modification	146	9.25e-10	2.60e-08	0.314	-0.2860	0.12900	2.45e-09	7.21e-03
Calnexin/calreticulin cycle	25	1.47e-09	4.06e-08	0.750	-0.6270	0.41200	5.76e-08	3.69e-04

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pMANOVA	p.adjustMANOVA	s.dist	s.x	s.abs	p.x	p.abs
Cellular responses to stimuli	641	2.71e-23	3.73e-20	0.241000	-0.222000	9.20e-02	1.36e-21	7.93e-05
Asparagine N-linked glycosylation	252	2.39e-22	1.64e-19	0.372000	-0.306000	2.12e-01	6.70e-17	7.65e-09
Cellular responses to stress	633	6.23e-22	2.86e-19	0.235000	-0.217000	8.98e-02	2.20e-20	1.29e-04
Cholesterol biosynthesis	24	2.36e-19	8.13e-17	1.070000	0.843000	6.59e-01	8.63e-13	2.32e-08
Infectious disease	637	9.29e-18	2.56e-15	0.208000	-0.206000	2.47e-02	1.06e-18	2.92e-01
Signal Transduction	1748	2.01e-17	4.62e-15	0.131000	-0.106000	7.77e-02	6.08e-13	1.28e-07
Unfolded Protein Response (UPR)	89	3.68e-17	7.23e-15	0.544000	-0.393000	3.76e-01	1.43e-10	9.26e-10
SRP-dependent cotranslational protein targeting to membrane	109	1.60e-16	2.75e-14	0.473000	-0.473000	2.29e-02	1.48e-17	6.80e-01
Metabolism of proteins	1550	1.40e-15	2.15e-13	0.130000	-0.118000	5.56e-02	3.25e-14	3.40e-04
Axon guidance	424	3.06e-15	3.88e-13	0.233000	-0.232000	9.35e-03	2.94e-16	7.42e-01
Immune System	1374	3.10e-15	3.88e-13	0.136000	-0.106000	8.55e-02	8.91e-11	1.75e-07
IRE1alpha activates chaperones	50	6.59e-15	7.56e-13	0.673000	-0.489000	4.63e-01	2.24e-09	1.48e-08
Innate Immune System	740	2.59e-14	2.75e-12	0.176000	-0.125000	1.23e-01	9.58e-09	1.49e-08
Cellular response to starvation	149	1.93e-13	1.90e-11	0.363000	-0.363000	4.55e-03	2.02e-14	9.24e-01
XBP1(S) activates chaperone genes	48	3.69e-13	3.38e-11	0.643000	-0.468000	4.42e-01	2.02e-08	1.21e-07
L13a-mediated translational silencing of Ceruloplasmin expression	108	5.33e-13	4.58e-11	0.415000	-0.404000	-9.45e-02	4.15e-13	9.02e-02
Nervous system development	444	5.72e-13	4.63e-11	0.209000	-0.209000	1.66e-02	6.25e-14	5.51e-01
GTP hydrolysis and joining of the 60S ribosomal subunit	109	9.36e-13	7.16e-11	0.409000	-0.399000	-8.81e-02	5.93e-13	1.13e-01
Formation of a pool of free 40S subunits	98	2.32e-12	1.61e-10	0.422000	-0.397000	-1.44e-01	1.12e-11	1.39e-02
Cap-dependent Translation Initiation	116	2.46e-12	1.61e-10	0.390000	-0.380000	-8.61e-02	1.61e-12	1.10e-01
Eukaryotic Translation Initiation	116	2.46e-12	1.61e-10	0.390000	-0.380000	-8.61e-02	1.61e-12	1.10e-01
Disease	1247	2.59e-12	1.62e-10	0.127000	-0.114000	5.50e-02	2.40e-11	1.30e-03
DNA strand elongation	32	3.14e-12	1.88e-10	0.729000	0.602000	4.11e-01	3.66e-09	5.82e-05
Complement cascade	35	3.47e-12	1.94e-10	0.695000	0.498000	4.85e-01	3.48e-07	6.84e-07
Developmental Biology	677	3.52e-12	1.94e-10	0.166000	-0.163000	2.81e-02	6.00e-13	2.17e-01
Translation	270	5.70e-12	3.02e-10	0.254000	-0.253000	-2.24e-02	9.51e-13	5.29e-01
Eukaryotic Translation Elongation	91	6.39e-12	3.17e-10	0.430000	-0.407000	-1.40e-01	2.06e-11	2.12e-02
Regulation of expression of SLITs and ROBOs	157	6.44e-12	3.17e-10	0.330000	-0.325000	-5.56e-02	2.15e-12	2.30e-01
Signaling by ROBO receptors	193	8.70e-12	4.13e-10	0.296000	-0.293000	-4.67e-02	2.58e-12	2.64e-01
Diseases of signal transduction by growth factor receptors and second messengers	361	1.36e-11	6.24e-10	0.219000	-0.214000	4.98e-02	3.78e-12	1.05e-01
Response of EIF2AK4 (GCN2) to amino acid deficiency	98	1.42e-11	6.29e-10	0.410000	-0.400000	-8.68e-02	7.59e-12	1.38e-01
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	34	1.79e-11	7.72e-10	0.710000	-0.574000	4.18e-01	7.03e-09	2.46e-05
Viral mRNA Translation	86	2.30e-11	9.61e-10	0.431000	-0.410000	-1.35e-01	5.18e-11	3.09e-02
Post-translational protein modification	1138	2.54e-11	1.03e-09	0.127000	-0.096700	8.22e-02	5.82e-08	4.03e-06
Peptide chain elongation	86	2.62e-11	1.03e-09	0.430000	-0.405000	-1.43e-01	8.24e-11	2.19e-02
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	91	2.70e-11	1.03e-09	0.419000	-0.406000	-1.05e-01	2.32e-11	8.42e-02
Regulation of Complement cascade	30	3.18e-11	1.18e-09	0.719000	0.555000	4.57e-01	1.43e-07	1.50e-05
rRNA processing in the nucleus and cytosol	184	4.11e-11	1.49e-09	0.292000	-0.278000	-8.94e-02	7.82e-11	3.68e-02
Metabolism of RNA	658	5.13e-11	1.81e-09	0.158000	-0.156000	-2.05e-02	1.16e-11	3.74e-01
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	111	5.72e-11	1.92e-09	0.374000	-0.364000	-8.70e-02	3.73e-11	1.14e-01
Nonsense-Mediated Decay (NMD)	111	5.72e-11	1.92e-09	0.374000	-0.364000	-8.70e-02	3.73e-11	1.14e-01
Major pathway of rRNA processing in the nucleolus and cytosol	174	1.64e-10	5.38e-09	0.292000	-0.280000	-8.21e-02	1.91e-10	6.24e-02
SARS-CoV Infections	144	1.93e-10	6.17e-09	0.327000	-0.312000	9.63e-02	1.05e-10	4.64e-02
Selenocysteine synthesis	89	2.72e-10	8.30e-09	0.402000	-0.375000	-1.44e-01	1.00e-09	1.89e-02
Eukaryotic Translation Termination	89	2.77e-10	8.30e-09	0.402000	-0.387000	-1.10e-01	2.80e-10	7.25e-02
Signaling by Receptor Tyrosine Kinases	405	2.77e-10	8.30e-09	0.196000	-0.179000	7.95e-02	7.81e-10	6.32e-03
Influenza Infection	151	3.58e-10	1.05e-08	0.310000	-0.309000	-2.92e-02	6.29e-11	5.37e-01
Transport of small molecules	535	5.27e-10	1.51e-08	0.169000	-0.128000	1.11e-01	4.55e-07	1.35e-05
Transport to the Golgi and subsequent modification	146	9.25e-10	2.60e-08	0.314000	-0.286000	1.29e-01	2.45e-09	7.21e-03
Calnexin/calreticulin cycle	25	1.47e-09	4.06e-08	0.750000	-0.627000	4.12e-01	5.76e-08	3.69e-04
Vesicle-mediated transport	555	2.92e-09	7.89e-08	0.158000	-0.154000	3.49e-02	7.17e-10	1.63e-01
Cell Cycle	594	4.37e-09	1.16e-07	0.147000	0.123000	8.12e-02	3.79e-07	7.91e-04
Signaling by Interleukins	315	4.73e-09	1.23e-07	0.207000	-0.175000	1.10e-01	9.78e-08	7.88e-04
Membrane Trafficking	531	5.71e-09	1.46e-07	0.158000	-0.156000	2.58e-02	9.78e-10	3.11e-01
Selenoamino acid metabolism	104	6.19e-09	1.55e-07	0.344000	-0.323000	-1.20e-01	1.30e-08	3.51e-02
ER to Golgi Anterograde Transport	122	7.78e-09	1.91e-07	0.325000	-0.299000	1.28e-01	1.24e-08	1.46e-02
Homologous DNA Pairing and Strand Exchange	42	1.33e-08	3.20e-07	0.529000	0.477000	2.27e-01	8.69e-08	1.09e-02
Biological oxidations	155	1.53e-08	3.62e-07	0.275000	0.245000	1.24e-01	1.42e-07	7.66e-03
Initial triggering of complement	12	1.73e-08	4.03e-07	0.977000	0.607000	7.65e-01	2.72e-04	4.38e-06
Activation of gene expression by SREBF (SREBP)	42	2.85e-08	6.55e-07	0.515000	0.335000	3.91e-01	1.71e-04	1.16e-05
Diseases of DNA repair	34	2.93e-08	6.61e-07	0.576000	0.547000	1.83e-01	3.47e-08	6.54e-02
PIP3 activates AKT signaling	223	3.91e-08	8.68e-07	0.229000	-0.226000	3.53e-02	6.57e-09	3.65e-01
SARS-CoV-2 Infection	69	4.11e-08	8.90e-07	0.413000	-0.361000	2.00e-01	2.16e-07	4.08e-03
Metabolism	1696	4.13e-08	8.90e-07	0.085600	0.034600	7.83e-02	2.04e-02	1.50e-07
Mitotic Prometaphase	181	5.36e-08	1.13e-06	0.246000	0.229000	9.15e-02	1.19e-07	3.41e-02
Resolution of D-loop Structures through Holliday Junction Intermediates	32	5.89e-08	1.23e-06	0.581000	0.540000	2.15e-01	1.27e-07	3.52e-02
rRNA processing	205	6.24e-08	1.28e-06	0.231000	-0.219000	-7.44e-02	7.31e-08	6.71e-02
Ribosomal scanning and start codon recognition	58	7.22e-08	1.46e-06	0.435000	-0.435000	-5.55e-03	1.02e-08	9.42e-01
Cell Cycle, Mitotic	478	8.54e-08	1.70e-06	0.150000	0.118000	9.23e-02	1.02e-05	5.90e-04
Influenza Viral RNA Transcription and Replication	132	8.96e-08	1.76e-06	0.285000	-0.276000	-7.01e-02	4.62e-08	1.65e-01
Regulation of cholesterol biosynthesis by SREBP (SREBF)	54	9.93e-08	1.93e-06	0.442000	0.109000	4.29e-01	1.67e-01	5.07e-08
Translation initiation complex formation	58	1.07e-07	2.04e-06	0.429000	-0.429000	-1.80e-02	1.63e-08	8.13e-01
Unwinding of DNA	12	1.39e-07	2.63e-06	0.919000	0.768000	5.05e-01	4.06e-06	2.48e-03
Fatty acid metabolism	130	1.63e-07	3.03e-06	0.279000	0.230000	1.58e-01	6.13e-06	1.91e-03
Homology Directed Repair	101	1.75e-07	3.22e-06	0.317000	0.289000	1.28e-01	5.14e-07	2.60e-02
Signaling by NTRK1 (TRKA)	102	1.81e-07	3.28e-06	0.323000	-0.305000	1.06e-01	1.00e-07	6.47e-02
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	26	2.04e-07	3.65e-06	0.618000	0.544000	2.94e-01	1.60e-06	9.45e-03
Resolution of D-Loop Structures	33	2.13e-07	3.75e-06	0.549000	0.506000	2.14e-01	4.98e-07	3.30e-02
Transferrin endocytosis and recycling	29	2.37e-07	4.14e-06	0.604000	-0.423000	4.32e-01	8.19e-05	5.72e-05
RHO GTPase cycle	387	2.49e-07	4.27e-06	0.167000	-0.147000	7.94e-02	8.32e-07	7.64e-03
HDR through Homologous Recombination (HRR)	66	2.51e-07	4.27e-06	0.386000	0.345000	1.74e-01	1.28e-06	1.48e-02
Defective HDR through Homologous Recombination (HRR) due to BRCA1 loss-of-function	24	3.01e-07	4.80e-06	0.636000	0.573000	2.75e-01	1.16e-06	1.99e-02
Defective HDR through Homologous Recombination (HRR) due to PALB2 loss of function	24	3.01e-07	4.80e-06	0.636000	0.573000	2.75e-01	1.16e-06	1.99e-02
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function	24	3.01e-07	4.80e-06	0.636000	0.573000	2.75e-01	1.16e-06	1.99e-02
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function	24	3.01e-07	4.80e-06	0.636000	0.573000	2.75e-01	1.16e-06	1.99e-02
Diseases of DNA Double-Strand Break Repair	24	3.01e-07	4.80e-06	0.636000	0.573000	2.75e-01	1.16e-06	1.99e-02
Formation of the ternary complex, and subsequently, the 43S complex	51	3.04e-07	4.80e-06	0.440000	-0.433000	-7.96e-02	8.98e-08	3.26e-01
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	59	3.25e-07	5.08e-06	0.411000	-0.410000	-1.32e-02	4.97e-08	8.61e-01
Neutrophil degranulation	352	4.20e-07	6.50e-06	0.172000	-0.114000	1.29e-01	2.53e-04	3.51e-05
Chromosome Maintenance	90	4.86e-07	7.44e-06	0.324000	0.295000	1.35e-01	1.39e-06	2.72e-02
Intracellular signaling by second messengers	252	5.14e-07	7.78e-06	0.198000	-0.197000	1.42e-02	7.50e-08	6.99e-01
Presynaptic phase of homologous DNA pairing and strand exchange	39	5.30e-07	7.93e-06	0.490000	0.449000	1.95e-01	1.19e-06	3.51e-02
ER Quality Control Compartment (ERQC)	20	6.72e-07	9.95e-06	0.700000	-0.611000	3.42e-01	2.26e-06	8.10e-03
MAPK family signaling cascades	244	8.25e-07	1.20e-05	0.200000	-0.189000	6.42e-02	3.99e-07	8.52e-02
Autophagy	121	8.29e-07	1.20e-05	0.282000	-0.271000	7.77e-02	2.79e-07	1.40e-01
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	19	8.56e-07	1.23e-05	0.713000	-0.580000	4.16e-01	1.22e-05	1.70e-03
Phase II - Conjugation of compounds	75	9.21e-07	1.31e-05	0.346000	0.299000	1.73e-01	7.40e-06	9.49e-03
Cytokine Signaling in Immune system	492	1.03e-06	1.45e-05	0.141000	-0.126000	6.41e-02	2.02e-06	1.55e-02
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	95	1.08e-06	1.50e-05	0.306000	0.275000	1.35e-01	3.73e-06	2.28e-02
Signaling by the B Cell Receptor (BCR)	96	1.96e-06	2.68e-05	0.304000	-0.303000	1.94e-02	2.97e-07	7.43e-01
Hedgehog ligand biogenesis	59	1.97e-06	2.68e-05	0.392000	-0.350000	1.76e-01	3.35e-06	1.91e-02
Defective CFTR causes cystic fibrosis	56	2.19e-06	2.96e-05	0.401000	-0.357000	1.81e-01	3.77e-06	1.90e-02
RAF/MAP kinase cascade	207	2.34e-06	3.12e-05	0.208000	-0.195000	7.27e-02	1.35e-06	7.22e-02
Insulin receptor recycling	23	2.45e-06	3.24e-05	0.623000	-0.524000	3.38e-01	1.37e-05	5.07e-03
Activation of ATR in response to replication stress	37	2.51e-06	3.30e-05	0.475000	0.427000	2.08e-01	7.05e-06	2.89e-02
TCR signaling	91	2.85e-06	3.70e-05	0.308000	-0.305000	4.07e-02	4.87e-07	5.03e-01
Hh mutants are degraded by ERAD	53	2.88e-06	3.71e-05	0.407000	-0.376000	1.56e-01	2.27e-06	4.96e-02
COPI-mediated anterograde transport	74	3.07e-06	3.92e-05	0.343000	-0.321000	1.21e-01	1.83e-06	7.10e-02
Cell Cycle Checkpoints	249	3.53e-06	4.45e-05	0.181000	0.148000	1.05e-01	6.20e-05	4.40e-03
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	99	3.56e-06	4.45e-05	0.291000	0.000729	2.91e-01	9.90e-01	5.59e-07
Macroautophagy	108	3.73e-06	4.62e-05	0.281000	-0.271000	7.72e-02	1.20e-06	1.66e-01
Hh mutants abrogate ligand secretion	55	3.79e-06	4.67e-05	0.395000	-0.363000	1.56e-01	3.23e-06	4.58e-02
Signaling by Rho GTPases, Miro GTPases and RHOBTB3	566	4.22e-06	5.15e-05	0.125000	-0.080600	9.62e-02	1.13e-03	1.02e-04
MyD88 cascade initiated on plasma membrane	77	4.40e-06	5.22e-05	0.331000	-0.318000	9.09e-02	1.41e-06	1.68e-01
Toll Like Receptor 10 (TLR10) Cascade	77	4.40e-06	5.22e-05	0.331000	-0.318000	9.09e-02	1.41e-06	1.68e-01
Toll Like Receptor 5 (TLR5) Cascade	77	4.40e-06	5.22e-05	0.331000	-0.318000	9.09e-02	1.41e-06	1.68e-01
Signaling by Insulin receptor	59	4.69e-06	5.52e-05	0.378000	-0.349000	1.46e-01	3.60e-06	5.29e-02
DNA Double-Strand Break Repair	127	4.84e-06	5.65e-05	0.251000	0.227000	1.05e-01	9.98e-06	4.05e-02
Telomere C-strand (Lagging Strand) Synthesis	34	5.19e-06	6.00e-05	0.480000	0.403000	2.60e-01	4.74e-05	8.66e-03
Fc epsilon receptor (FCERI) signaling	113	5.26e-06	6.01e-05	0.268000	-0.268000	-4.55e-03	8.53e-07	9.33e-01
MAPK1/MAPK3 signaling	212	5.28e-06	6.01e-05	0.199000	-0.186000	7.32e-02	3.38e-06	6.70e-02
ABC transporter disorders	70	5.37e-06	6.06e-05	0.347000	-0.277000	2.09e-01	6.06e-05	2.55e-03
Post-translational protein phosphorylation	91	6.75e-06	7.55e-05	0.297000	-0.030600	2.96e-01	6.14e-01	1.12e-06
EML4 and NUDC in mitotic spindle formation	94	7.50e-06	8.32e-05	0.284000	0.210000	1.91e-01	4.25e-04	1.37e-03
Lagging Strand Synthesis	20	7.95e-06	8.76e-05	0.614000	0.502000	3.54e-01	1.02e-04	6.19e-03
Mitotic Spindle Checkpoint	107	8.30e-06	9.08e-05	0.266000	0.217000	1.53e-01	1.03e-04	6.40e-03
Signaling by NTRKs	115	9.52e-06	1.03e-04	0.262000	-0.254000	6.34e-02	2.52e-06	2.41e-01
Downstream signaling events of B Cell Receptor (BCR)	74	9.76e-06	1.05e-04	0.324000	-0.323000	3.28e-02	1.63e-06	6.26e-01
MyD88 dependent cascade initiated on endosome	81	1.01e-05	1.06e-04	0.311000	-0.301000	7.96e-02	2.86e-06	2.16e-01
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	81	1.01e-05	1.06e-04	0.311000	-0.301000	7.96e-02	2.86e-06	2.16e-01
Toll Like Receptor 7/8 (TLR7/8) Cascade	81	1.01e-05	1.06e-04	0.311000	-0.301000	7.96e-02	2.86e-06	2.16e-01
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	90	1.04e-05	1.08e-04	0.286000	0.208000	1.97e-01	6.63e-04	1.24e-03
Amplification of signal from the kinetochores	90	1.04e-05	1.08e-04	0.286000	0.208000	1.97e-01	6.63e-04	1.24e-03
Signaling by WNT	213	1.13e-05	1.16e-04	0.191000	-0.190000	1.96e-02	1.90e-06	6.23e-01
Activation of the pre-replicative complex	32	1.17e-05	1.19e-04	0.478000	0.392000	2.73e-01	1.24e-04	7.58e-03
Toll Like Receptor 3 (TLR3) Cascade	85	1.19e-05	1.20e-04	0.299000	-0.299000	9.69e-03	1.91e-06	8.77e-01
Toll Like Receptor 9 (TLR9) Cascade	85	1.35e-05	1.36e-04	0.300000	-0.290000	7.55e-02	3.75e-06	2.29e-01
Iron uptake and transport	55	1.45e-05	1.45e-04	0.375000	-0.287000	2.41e-01	2.28e-04	1.99e-03
Signaling by Rho GTPases	551	1.58e-05	1.56e-04	0.120000	-0.073900	9.47e-02	3.22e-03	1.57e-04
MyD88 deficiency (TLR2/4)	11	1.74e-05	1.71e-04	0.800000	0.686000	4.13e-01	8.20e-05	1.78e-02
RAC3 GTPase cycle	79	2.23e-05	2.18e-04	0.306000	-0.280000	1.23e-01	1.72e-05	5.92e-02
Processive synthesis on the lagging strand	15	2.30e-05	2.23e-04	0.676000	0.552000	3.90e-01	2.13e-04	8.93e-03
Regulation of HMOX1 expression and activity	62	2.35e-05	2.26e-04	0.343000	-0.322000	1.20e-01	1.18e-05	1.03e-01
Downstream TCR signaling	76	2.56e-05	2.45e-04	0.307000	-0.303000	4.81e-02	4.96e-06	4.69e-01
Resolution of Sister Chromatid Cohesion	103	2.66e-05	2.53e-04	0.257000	0.206000	1.53e-01	3.00e-04	7.34e-03
ABC-family proteins mediated transport	92	2.72e-05	2.56e-04	0.282000	-0.242000	1.44e-01	6.17e-05	1.70e-02
MyD88-independent TLR4 cascade	88	2.92e-05	2.72e-04	0.282000	-0.282000	3.22e-03	4.92e-06	9.58e-01
TRIF(TICAM1)-mediated TLR4 signaling	88	2.92e-05	2.72e-04	0.282000	-0.282000	3.22e-03	4.92e-06	9.58e-01
Degradation of beta-catenin by the destruction complex	80	3.22e-05	2.98e-04	0.297000	-0.288000	7.19e-02	8.54e-06	2.67e-01
Metabolism of lipids	592	3.60e-05	3.30e-04	0.109000	0.012400	1.08e-01	6.09e-01	7.79e-06
DNA Repair	276	3.68e-05	3.36e-04	0.156000	0.148000	5.13e-02	2.51e-05	1.44e-01
Interleukin-1 signaling	92	4.12e-05	3.69e-04	0.275000	-0.255000	1.02e-01	2.33e-05	9.27e-02
Deposition of new CENPA-containing nucleosomes at the centromere	27	4.13e-05	3.69e-04	0.494000	0.478000	1.25e-01	1.69e-05	2.61e-01
Nucleosome assembly	27	4.13e-05	3.69e-04	0.494000	0.478000	1.25e-01	1.69e-05	2.61e-01
trans-Golgi Network Vesicle Budding	68	4.21e-05	3.74e-04	0.319000	-0.300000	1.07e-01	1.85e-05	1.29e-01
Hemostasis	409	4.36e-05	3.81e-04	0.131000	-0.048100	1.22e-01	9.69e-02	2.39e-05
HDR through Single Strand Annealing (SSA)	37	4.36e-05	3.81e-04	0.421000	0.400000	1.29e-01	2.53e-05	1.74e-01
Deubiquitination	218	4.37e-05	3.81e-04	0.179000	-0.167000	6.50e-02	2.36e-05	9.92e-02
Adaptive Immune System	551	4.42e-05	3.83e-04	0.113000	-0.110000	2.90e-02	1.25e-05	2.47e-01
Chromatin modifying enzymes	195	4.56e-05	3.90e-04	0.187000	-0.186000	1.99e-02	8.16e-06	6.32e-01
Chromatin organization	195	4.56e-05	3.90e-04	0.187000	-0.186000	1.99e-02	8.16e-06	6.32e-01
MAP kinase activation	61	4.61e-05	3.92e-04	0.333000	-0.327000	6.64e-02	1.03e-05	3.70e-01
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	31	4.93e-05	4.17e-04	0.471000	-0.292000	3.70e-01	4.90e-03	3.70e-04
PTEN Regulation	134	5.28e-05	4.43e-04	0.224000	-0.220000	3.86e-02	1.09e-05	4.41e-01
Leading Strand Synthesis	14	5.50e-05	4.56e-04	0.670000	0.544000	3.92e-01	4.25e-04	1.11e-02
Polymerase switching	14	5.50e-05	4.56e-04	0.670000	0.544000	3.92e-01	4.25e-04	1.11e-02
IRAK4 deficiency (TLR2/4)	12	5.59e-05	4.60e-04	0.725000	0.646000	3.31e-01	1.08e-04	4.71e-02
Activation of NF-kappaB in B cells	62	5.61e-05	4.60e-04	0.327000	-0.323000	4.56e-02	1.07e-05	5.35e-01
COPII-mediated vesicle transport	63	5.77e-05	4.70e-04	0.326000	-0.306000	1.13e-01	2.73e-05	1.21e-01
Platelet degranulation	103	6.06e-05	4.91e-04	0.251000	0.010600	2.51e-01	8.53e-01	1.12e-05
Cilium Assembly	172	6.16e-05	4.96e-04	0.194000	0.192000	2.53e-02	1.43e-05	5.67e-01
RAC2 GTPase cycle	75	6.34e-05	5.08e-04	0.298000	-0.275000	1.14e-01	3.85e-05	8.78e-02
Cytoprotection by HMOX1	118	6.78e-05	5.39e-04	0.237000	-0.223000	7.92e-02	2.94e-05	1.38e-01
Interleukin-17 signaling	65	6.86e-05	5.43e-04	0.316000	-0.312000	5.32e-02	1.41e-05	4.58e-01
Signaling by NOTCH	156	7.04e-05	5.54e-04	0.206000	-0.191000	7.71e-02	3.98e-05	9.71e-02
Regulation of TLR by endogenous ligand	12	7.76e-05	6.07e-04	0.712000	0.601000	3.81e-01	3.09e-04	2.23e-02
Interleukin-12 signaling	38	8.24e-05	6.41e-04	0.415000	-0.269000	3.15e-01	4.14e-03	7.67e-04
Extension of Telomeres	50	8.50e-05	6.57e-04	0.348000	0.297000	1.81e-01	2.83e-04	2.70e-02
UCH proteinases	81	9.31e-05	7.15e-04	0.280000	-0.270000	7.15e-02	2.63e-05	2.66e-01
Circadian Clock	65	9.35e-05	7.15e-04	0.313000	-0.289000	1.21e-01	5.64e-05	9.18e-02
Amino acid transport across the plasma membrane	28	1.00e-04	7.63e-04	0.477000	-0.379000	2.91e-01	5.25e-04	7.75e-03
Removal of the Flap Intermediate	14	1.01e-04	7.63e-04	0.650000	0.532000	3.73e-01	5.71e-04	1.57e-02
Interleukin-1 family signaling	111	1.03e-04	7.78e-04	0.239000	-0.215000	1.05e-01	9.25e-05	5.67e-02
Regulation of RUNX2 expression and activity	62	1.04e-04	7.81e-04	0.318000	-0.303000	9.52e-02	3.63e-05	1.95e-01
Base Excision Repair	45	1.14e-04	8.49e-04	0.361000	0.324000	1.61e-01	1.74e-04	6.25e-02
Polymerase switching on the C-strand of the telomere	26	1.36e-04	1.01e-03	0.469000	0.387000	2.65e-01	6.31e-04	1.95e-02
ROS sensing by NFE2L2	54	1.49e-04	1.09e-03	0.333000	-0.322000	8.62e-02	4.25e-05	2.73e-01
Negative regulation of MAPK pathway	41	1.49e-04	1.09e-03	0.384000	-0.356000	1.44e-01	7.97e-05	1.12e-01
Response of EIF2AK1 (HRI) to heme deficiency	15	1.53e-04	1.12e-03	0.637000	-0.443000	4.58e-01	2.96e-03	2.13e-03
Disorders of transmembrane transporters	140	1.70e-04	1.23e-03	0.208000	-0.148000	1.47e-01	2.57e-03	2.75e-03
Transcriptional regulation by RUNX3	91	1.77e-04	1.27e-03	0.257000	-0.223000	1.27e-01	2.37e-04	3.69e-02
Response to elevated platelet cytosolic Ca2+	106	1.78e-04	1.27e-03	0.233000	0.017400	2.32e-01	7.57e-01	3.66e-05
Metabolism of steroids	130	1.78e-04	1.27e-03	0.208000	0.091300	1.87e-01	7.27e-02	2.40e-04
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	64	1.96e-04	1.39e-03	0.304000	-0.155000	2.61e-01	3.17e-02	3.04e-04
Platelet activation, signaling and aggregation	189	2.00e-04	1.41e-03	0.177000	-0.086600	1.55e-01	4.04e-02	2.51e-04
Cargo concentration in the ER	27	2.01e-04	1.41e-03	0.465000	-0.434000	1.66e-01	9.54e-05	1.35e-01
Amino acids regulate mTORC1	51	2.12e-04	1.48e-03	0.339000	-0.288000	1.79e-01	3.84e-04	2.67e-02
Degradation of AXIN	52	2.24e-04	1.56e-03	0.331000	-0.324000	6.97e-02	5.39e-05	3.85e-01
Plasma lipoprotein remodeling	29	2.41e-04	1.67e-03	0.432000	0.156000	4.03e-01	1.46e-01	1.74e-04
Nuclear Events (kinase and transcription factor activation)	56	2.49e-04	1.72e-03	0.318000	-0.307000	8.35e-02	7.25e-05	2.80e-01
FCERI mediated NF-kB activation	70	2.63e-04	1.81e-03	0.282000	-0.280000	3.28e-02	5.17e-05	6.35e-01
TGF-beta receptor signaling activates SMADs	31	2.84e-04	1.94e-03	0.425000	-0.398000	1.49e-01	1.27e-04	1.52e-01
Cellular response to chemical stress	145	3.11e-04	2.11e-03	0.195000	-0.188000	5.19e-02	9.16e-05	2.82e-01
Regulation of PTEN stability and activity	64	3.17e-04	2.13e-03	0.292000	-0.289000	4.19e-02	6.54e-05	5.63e-01
Potential therapeutics for SARS	77	3.18e-04	2.13e-03	0.265000	-0.265000	8.18e-03	5.98e-05	9.01e-01
ROS and RNS production in phagocytes	27	3.20e-04	2.14e-03	0.454000	-0.391000	2.30e-01	4.38e-04	3.85e-02
RHO GTPases Activate Formins	116	3.30e-04	2.20e-03	0.211000	0.117000	1.76e-01	2.96e-02	1.07e-03
RHOQ GTPase cycle	54	3.41e-04	2.25e-03	0.321000	-0.243000	2.09e-01	2.03e-03	7.81e-03
C-type lectin receptors (CLRs)	113	3.53e-04	2.32e-03	0.218000	-0.217000	1.30e-02	6.70e-05	8.12e-01
Collagen chain trimerization	18	3.77e-04	2.47e-03	0.532000	0.478000	2.32e-01	4.42e-04	8.78e-02
Formation of Fibrin Clot (Clotting Cascade)	28	3.86e-04	2.52e-03	0.426000	0.383000	1.86e-01	4.53e-04	8.79e-02
Regulation of mRNA stability by proteins that bind AU-rich elements	86	3.89e-04	2.52e-03	0.249000	-0.246000	3.69e-02	8.18e-05	5.54e-01
Interleukin-12 family signaling	46	3.89e-04	2.52e-03	0.344000	-0.220000	2.65e-01	9.79e-03	1.90e-03
RHOG GTPase cycle	66	3.91e-04	2.52e-03	0.286000	-0.265000	1.07e-01	1.96e-04	1.34e-01
RAC1 GTPase cycle	149	3.94e-04	2.52e-03	0.190000	-0.181000	5.74e-02	1.36e-04	2.27e-01
TCF dependent signaling in response to WNT	145	4.03e-04	2.57e-03	0.191000	-0.190000	1.44e-02	7.77e-05	7.65e-01
Intra-Golgi and retrograde Golgi-to-ER traffic	170	4.22e-04	2.68e-03	0.178000	-0.161000	7.60e-02	2.96e-04	8.80e-02
Transcriptional regulation by RUNX1	147	4.42e-04	2.79e-03	0.191000	-0.165000	9.74e-02	5.80e-04	4.19e-02
Regulation of RUNX3 expression and activity	54	4.43e-04	2.79e-03	0.312000	-0.302000	7.69e-02	1.22e-04	3.29e-01
Apoptotic execution phase	39	4.48e-04	2.80e-03	0.367000	-0.102000	3.53e-01	2.71e-01	1.39e-04
mRNA Splicing - Major Pathway	178	4.73e-04	2.95e-03	0.170000	-0.170000	-5.48e-03	9.49e-05	9.00e-01
Glutathione conjugation	29	4.95e-04	3.07e-03	0.413000	0.390000	1.35e-01	2.74e-04	2.07e-01
Lysosome Vesicle Biogenesis	31	4.97e-04	3.07e-03	0.410000	-0.381000	1.52e-01	2.40e-04	1.44e-01
Collagen degradation	20	5.07e-04	3.11e-03	0.503000	-0.005900	5.03e-01	9.64e-01	9.85e-05
Dectin-1 mediated noncanonical NF-kB signaling	58	5.19e-04	3.18e-03	0.294000	-0.292000	-3.10e-02	1.19e-04	6.83e-01
CLEC7A (Dectin-1) signaling	92	5.33e-04	3.24e-03	0.235000	-0.234000	7.49e-03	1.03e-04	9.01e-01
Response of Mtb to phagocytosis	21	5.37e-04	3.26e-03	0.499000	-0.387000	3.14e-01	2.12e-03	1.28e-02
ATF6 (ATF6-alpha) activates chaperones	12	5.40e-04	3.26e-03	0.659000	-0.424000	5.05e-01	1.10e-02	2.46e-03
Transport of inorganic cations/anions and amino acids/oligopeptides	71	5.41e-04	3.26e-03	0.270000	-0.252000	9.55e-02	2.40e-04	1.64e-01
Telomere Maintenance	65	5.58e-04	3.34e-03	0.273000	0.230000	1.46e-01	1.35e-03	4.14e-02
Signaling by VEGF	89	5.65e-04	3.37e-03	0.238000	-0.237000	1.62e-02	1.11e-04	7.92e-01
Synthesis of substrates in N-glycan biosythesis	49	5.86e-04	3.47e-03	0.324000	-0.157000	2.83e-01	5.77e-02	6.01e-04
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	34	5.87e-04	3.47e-03	0.388000	-0.167000	3.50e-01	9.21e-02	4.08e-04
NIK–>noncanonical NF-kB signaling	56	5.90e-04	3.47e-03	0.297000	-0.297000	-1.26e-02	1.21e-04	8.71e-01
ATF6 (ATF6-alpha) activates chaperone genes	10	6.13e-04	3.59e-03	0.716000	-0.474000	5.37e-01	9.43e-03	3.30e-03
Infection with Mycobacterium tuberculosis	22	6.39e-04	3.73e-03	0.481000	-0.386000	2.87e-01	1.71e-03	1.98e-02
Meiotic recombination	22	6.87e-04	3.99e-03	0.462000	0.406000	2.20e-01	9.76e-04	7.37e-02
mRNA Splicing	186	6.96e-04	4.03e-03	0.162000	-0.162000	-3.36e-03	1.41e-04	9.37e-01
PCP/CE pathway	79	7.37e-04	4.24e-03	0.250000	-0.236000	8.45e-02	2.96e-04	1.95e-01
HDMs demethylate histones	21	7.50e-04	4.30e-03	0.487000	-0.411000	2.61e-01	1.12e-03	3.86e-02
MAPK6/MAPK4 signaling	79	7.57e-04	4.33e-03	0.249000	-0.244000	4.69e-02	1.78e-04	4.71e-01
Ubiquitin-dependent degradation of Cyclin D	49	8.25e-04	4.69e-03	0.313000	-0.308000	5.40e-02	1.88e-04	5.13e-01
Ethanol oxidation	10	8.33e-04	4.72e-03	0.674000	0.479000	4.73e-01	8.67e-03	9.53e-03
AUF1 (hnRNP D0) binds and destabilizes mRNA	52	8.66e-04	4.89e-03	0.303000	-0.298000	5.86e-02	2.07e-04	4.65e-01
Cell-extracellular matrix interactions	14	8.72e-04	4.90e-03	0.591000	-0.460000	3.70e-01	2.88e-03	1.65e-02
Signaling by TGF-beta Receptor Complex	73	9.18e-04	5.11e-03	0.256000	-0.244000	7.84e-02	3.19e-04	2.47e-01
M Phase	339	9.19e-04	5.11e-03	0.116000	0.081900	8.25e-02	9.84e-03	9.32e-03
Heme signaling	42	9.20e-04	5.11e-03	0.337000	-0.323000	9.41e-02	2.87e-04	2.92e-01
Degradation of GLI1 by the proteasome	55	9.99e-04	5.53e-03	0.291000	-0.290000	2.35e-02	2.04e-04	7.63e-01
Signalling to ERKs	31	1.01e-03	5.56e-03	0.390000	-0.364000	1.41e-01	4.50e-04	1.75e-01
Cellular response to heat stress	91	1.06e-03	5.81e-03	0.229000	-0.158000	1.66e-01	9.35e-03	6.21e-03
Anchoring of the basal body to the plasma membrane	93	1.07e-03	5.83e-03	0.222000	0.222000	5.76e-03	2.23e-04	9.24e-01
Resolution of Abasic Sites (AP sites)	37	1.08e-03	5.88e-03	0.346000	0.322000	1.27e-01	6.97e-04	1.82e-01
Degradation of DVL	53	1.10e-03	5.88e-03	0.295000	-0.290000	5.22e-02	2.57e-04	5.11e-01
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	88	1.10e-03	5.88e-03	0.232000	-0.200000	1.17e-01	1.19e-03	5.86e-02
Toll Like Receptor 2 (TLR2) Cascade	88	1.10e-03	5.88e-03	0.232000	-0.200000	1.17e-01	1.19e-03	5.86e-02
Toll Like Receptor TLR1:TLR2 Cascade	88	1.10e-03	5.88e-03	0.232000	-0.200000	1.17e-01	1.19e-03	5.86e-02
Toll Like Receptor TLR6:TLR2 Cascade	88	1.10e-03	5.88e-03	0.232000	-0.200000	1.17e-01	1.19e-03	5.86e-02
Degradation of GLI2 by the proteasome	55	1.12e-03	5.91e-03	0.288000	-0.287000	1.91e-02	2.28e-04	8.07e-01
GLI3 is processed to GLI3R by the proteasome	55	1.12e-03	5.91e-03	0.288000	-0.287000	1.91e-02	2.28e-04	8.07e-01
AURKA Activation by TPX2	69	1.16e-03	6.13e-03	0.256000	0.256000	4.04e-03	2.42e-04	9.54e-01
Regulation of activated PAK-2p34 by proteasome mediated degradation	47	1.17e-03	6.16e-03	0.312000	-0.305000	6.59e-02	2.97e-04	4.35e-01
Golgi Associated Vesicle Biogenesis	55	1.18e-03	6.16e-03	0.289000	-0.280000	7.14e-02	3.31e-04	3.60e-01
Toll-like Receptor Cascades	126	1.18e-03	6.16e-03	0.192000	-0.181000	6.39e-02	4.59e-04	2.16e-01
Ub-specific processing proteases	150	1.33e-03	6.91e-03	0.174000	-0.170000	3.59e-02	3.35e-04	4.49e-01
Uptake and actions of bacterial toxins	22	1.35e-03	6.98e-03	0.454000	-0.421000	1.68e-01	6.22e-04	1.73e-01
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	51	1.46e-03	7.51e-03	0.293000	-0.293000	1.65e-02	3.02e-04	8.39e-01
Integrin cell surface interactions	45	1.50e-03	7.71e-03	0.305000	0.226000	2.04e-01	8.68e-03	1.80e-02
Signaling by NOTCH4	75	1.51e-03	7.71e-03	0.244000	-0.226000	9.25e-02	7.22e-04	1.66e-01
Regulation of HSF1-mediated heat shock response	74	1.56e-03	7.97e-03	0.246000	-0.152000	1.94e-01	2.42e-02	3.87e-03
Base-Excision Repair, AP Site Formation	18	1.59e-03	8.08e-03	0.480000	0.418000	2.36e-01	2.12e-03	8.32e-02
Telomere C-strand synthesis initiation	13	1.65e-03	8.37e-03	0.562000	0.385000	4.09e-01	1.61e-02	1.07e-02
PI Metabolism	71	1.69e-03	8.52e-03	0.242000	-0.231000	-7.48e-02	7.89e-04	2.76e-01
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	22	1.77e-03	8.90e-03	0.447000	-0.355000	2.71e-01	3.93e-03	2.78e-02
Apoptosis	153	1.78e-03	8.90e-03	0.170000	-0.136000	1.03e-01	3.86e-03	2.85e-02
Processive synthesis on the C-strand of the telomere	19	1.79e-03	8.91e-03	0.462000	0.377000	2.68e-01	4.50e-03	4.28e-02
Peroxisomal protein import	57	1.80e-03	8.93e-03	0.267000	0.225000	1.45e-01	3.37e-03	5.84e-02
Processing of Capped Intron-Containing Pre-mRNA	236	1.80e-03	8.93e-03	0.134000	-0.134000	-4.41e-03	3.92e-04	9.07e-01
Common Pathway of Fibrin Clot Formation	16	1.83e-03	9.04e-03	0.502000	0.360000	3.50e-01	1.26e-02	1.53e-02
Cleavage of the damaged pyrimidine	16	1.91e-03	9.31e-03	0.502000	0.422000	2.72e-01	3.50e-03	5.99e-02
Depyrimidination	16	1.91e-03	9.31e-03	0.502000	0.422000	2.72e-01	3.50e-03	5.99e-02
Recognition and association of DNA glycosylase with site containing an affected pyrimidine	16	1.91e-03	9.31e-03	0.502000	0.422000	2.72e-01	3.50e-03	5.99e-02
RND2 GTPase cycle	37	1.92e-03	9.35e-03	0.343000	-0.267000	2.15e-01	5.03e-03	2.36e-02
Transcriptional regulation by RUNX2	96	1.93e-03	9.38e-03	0.211000	-0.206000	4.39e-02	4.96e-04	4.58e-01
PI3K/AKT Signaling in Cancer	68	1.98e-03	9.55e-03	0.247000	-0.247000	3.86e-05	4.22e-04	1.00e+00
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	14	2.04e-03	9.82e-03	0.534000	0.470000	2.54e-01	2.34e-03	9.99e-02
Cellular response to hypoxia	72	2.05e-03	9.82e-03	0.242000	-0.237000	4.64e-02	5.07e-04	4.96e-01
Downregulation of TGF-beta receptor signaling	25	2.16e-03	1.03e-02	0.410000	-0.387000	1.36e-01	8.23e-04	2.41e-01
Signaling by EGFR	44	2.18e-03	1.04e-02	0.306000	-0.305000	1.52e-02	4.63e-04	8.62e-01
DNA Replication	127	2.24e-03	1.06e-02	0.176000	0.108000	1.40e-01	3.66e-02	6.66e-03
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	63	2.28e-03	1.08e-02	0.256000	-0.251000	5.09e-02	5.75e-04	4.85e-01
TNFR2 non-canonical NF-kB pathway	77	2.34e-03	1.11e-02	0.226000	-0.201000	-1.02e-01	2.26e-03	1.22e-01
RUNX1 regulates transcription of genes involved in differentiation of HSCs	61	2.38e-03	1.12e-02	0.260000	-0.253000	5.82e-02	6.38e-04	4.32e-01
Autodegradation of the E3 ubiquitin ligase COP1	49	2.40e-03	1.13e-02	0.288000	-0.287000	2.45e-02	5.22e-04	7.67e-01
Negative regulation of NOTCH4 signaling	52	2.41e-03	1.13e-02	0.278000	-0.278000	-1.98e-03	5.25e-04	9.80e-01
Hedgehog ‘on’ state	75	2.43e-03	1.13e-02	0.235000	-0.220000	8.09e-02	9.78e-04	2.26e-01
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	14	2.44e-03	1.13e-02	0.526000	0.463000	2.50e-01	2.72e-03	1.05e-01
Recruitment of NuMA to mitotic centrosomes	77	2.58e-03	1.19e-02	0.229000	0.227000	-3.27e-02	5.95e-04	6.20e-01
VEGFA-VEGFR2 Pathway	83	2.58e-03	1.19e-02	0.219000	-0.219000	-4.80e-03	5.69e-04	9.40e-01
RHOF GTPase cycle	40	2.70e-03	1.24e-02	0.321000	-0.220000	2.34e-01	1.63e-02	1.06e-02
LDL clearance	19	2.82e-03	1.29e-02	0.463000	-0.328000	3.26e-01	1.32e-02	1.38e-02
RHOV GTPase cycle	35	2.88e-03	1.31e-02	0.339000	-0.311000	1.35e-01	1.47e-03	1.66e-01
Ion channel transport	116	2.88e-03	1.31e-02	0.187000	-0.159000	9.86e-02	3.09e-03	6.69e-02
Scavenging by Class A Receptors	11	2.90e-03	1.31e-02	0.607000	-0.472000	3.81e-01	6.71e-03	2.87e-02
RHOJ GTPase cycle	49	2.91e-03	1.31e-02	0.288000	-0.217000	1.89e-01	8.57e-03	2.22e-02
Class I MHC mediated antigen processing & presentation	331	3.01e-03	1.35e-02	0.110000	-0.106000	3.13e-02	9.63e-04	3.29e-01
Regulation of RAS by GAPs	62	3.03e-03	1.36e-02	0.250000	-0.250000	4.41e-03	6.62e-04	9.52e-01
Fanconi Anemia Pathway	36	3.14e-03	1.40e-02	0.324000	0.317000	6.95e-02	1.01e-03	4.71e-01
Loss of Nlp from mitotic centrosomes	66	3.17e-03	1.41e-02	0.241000	0.241000	-1.31e-03	6.97e-04	9.85e-01
Loss of proteins required for interphase microtubule organization from the centrosome	66	3.17e-03	1.41e-02	0.241000	0.241000	-1.31e-03	6.97e-04	9.85e-01
Beta-catenin independent WNT signaling	117	3.25e-03	1.44e-02	0.183000	-0.175000	5.45e-02	1.09e-03	3.09e-01
Centrosome maturation	78	3.27e-03	1.44e-02	0.224000	0.216000	-5.94e-02	9.92e-04	3.65e-01
Recruitment of mitotic centrosome proteins and complexes	78	3.27e-03	1.44e-02	0.224000	0.216000	-5.94e-02	9.92e-04	3.65e-01
Regulation of TP53 Activity through Acetylation	29	3.33e-03	1.46e-02	0.361000	-0.360000	-2.54e-02	7.88e-04	8.13e-01
Inactivation, recovery and regulation of the phototransduction cascade	20	3.38e-03	1.48e-02	0.432000	-0.094000	-4.21e-01	4.67e-01	1.11e-03
COPI-dependent Golgi-to-ER retrograde traffic	75	3.46e-03	1.51e-02	0.229000	-0.107000	2.02e-01	1.09e-01	2.52e-03
NOTCH4 Intracellular Domain Regulates Transcription	15	3.51e-03	1.53e-02	0.502000	-0.033300	5.01e-01	8.23e-01	7.77e-04
Vif-mediated degradation of APOBEC3G	51	3.66e-03	1.58e-02	0.273000	-0.270000	3.89e-02	8.63e-04	6.31e-01
SARS-CoV-1 Infection	48	3.74e-03	1.61e-02	0.284000	-0.252000	1.31e-01	2.57e-03	1.18e-01
RHOC GTPase cycle	67	3.78e-03	1.63e-02	0.241000	-0.189000	1.49e-01	7.55e-03	3.50e-02
Clathrin-mediated endocytosis	116	3.84e-03	1.65e-02	0.181000	-0.178000	2.97e-02	9.37e-04	5.82e-01
Regulation of ornithine decarboxylase (ODC)	48	3.87e-03	1.66e-02	0.279000	-0.277000	3.31e-02	8.92e-04	6.92e-01
G2/M DNA damage checkpoint	60	3.93e-03	1.68e-02	0.246000	0.239000	6.04e-02	1.41e-03	4.19e-01
Toll Like Receptor 4 (TLR4) Cascade	110	3.99e-03	1.69e-02	0.186000	-0.172000	7.00e-02	1.80e-03	2.05e-01
SCF-beta-TrCP mediated degradation of Emi1	52	4.06e-03	1.72e-02	0.267000	-0.266000	1.63e-02	9.06e-04	8.39e-01
Uptake and function of anthrax toxins	11	4.13e-03	1.74e-02	0.586000	-0.518000	2.74e-01	2.92e-03	1.16e-01
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism	12	4.23e-03	1.78e-02	0.542000	0.246000	4.83e-01	1.39e-01	3.78e-03
alpha-linolenic acid (ALA) metabolism	12	4.23e-03	1.78e-02	0.542000	0.246000	4.83e-01	1.39e-01	3.78e-03
Regulation of Apoptosis	50	4.44e-03	1.86e-02	0.271000	-0.267000	4.40e-02	1.09e-03	5.91e-01
MHC class II antigen presentation	84	4.45e-03	1.86e-02	0.212000	-0.124000	1.72e-01	5.02e-02	6.52e-03
Nuclear Receptor transcription pathway	41	4.48e-03	1.86e-02	0.301000	-0.279000	1.11e-01	1.97e-03	2.17e-01
AKT phosphorylates targets in the cytosol	13	4.58e-03	1.90e-02	0.528000	-0.524000	6.35e-02	1.07e-03	6.92e-01
Retrograde transport at the Trans-Golgi-Network	48	4.71e-03	1.95e-02	0.277000	-0.255000	1.08e-01	2.25e-03	1.95e-01
Cross-presentation of soluble exogenous antigens (endosomes)	42	4.75e-03	1.96e-02	0.294000	-0.286000	6.99e-02	1.35e-03	4.34e-01
Negative regulation of the PI3K/AKT network	74	4.87e-03	2.00e-02	0.222000	-0.211000	6.78e-02	1.68e-03	3.13e-01
Host Interactions of HIV factors	122	4.95e-03	2.03e-02	0.172000	-0.170000	2.13e-02	1.17e-03	6.85e-01
SLC-mediated transmembrane transport	174	5.05e-03	2.06e-02	0.146000	-0.097300	1.09e-01	2.71e-02	1.35e-02
Assembly of active LPL and LIPC lipase complexes	16	5.06e-03	2.06e-02	0.460000	0.307000	3.42e-01	3.33e-02	1.77e-02
TBC/RABGAPs	43	5.07e-03	2.06e-02	0.290000	-0.276000	8.82e-02	1.74e-03	3.17e-01
ESR-mediated signaling	138	5.25e-03	2.13e-02	0.162000	-0.149000	6.32e-02	2.49e-03	2.00e-01
Phase I - Functionalization of compounds	74	5.64e-03	2.28e-02	0.213000	0.192000	9.17e-02	4.26e-03	1.73e-01
Peroxisomal lipid metabolism	26	5.77e-03	2.32e-02	0.357000	0.292000	2.05e-01	9.99e-03	7.00e-02
PERK regulates gene expression	31	5.91e-03	2.37e-02	0.339000	-0.278000	1.94e-01	7.50e-03	6.17e-02
Advanced glycosylation endproduct receptor signaling	10	6.13e-03	2.45e-02	0.594000	-0.390000	4.48e-01	3.27e-02	1.41e-02
Mismatch Repair	15	6.17e-03	2.46e-02	0.469000	0.435000	1.75e-01	3.54e-03	2.40e-01
MAPK targets/ Nuclear events mediated by MAP kinases	30	6.37e-03	2.54e-02	0.338000	-0.331000	6.62e-02	1.69e-03	5.30e-01
Termination of translesion DNA synthesis	32	6.42e-03	2.55e-02	0.319000	0.165000	2.73e-01	1.07e-01	7.57e-03
Antigen processing-Cross presentation	87	6.51e-03	2.58e-02	0.200000	-0.173000	1.00e-01	5.21e-03	1.07e-01
Regulation of actin dynamics for phagocytic cup formation	49	6.57e-03	2.59e-02	0.262000	-0.262000	1.64e-02	1.53e-03	8.42e-01
Mitotic Anaphase	221	6.58e-03	2.59e-02	0.122000	0.063900	1.04e-01	1.03e-01	8.05e-03
MAP3K8 (TPL2)-dependent MAPK1/3 activation	16	6.62e-03	2.60e-02	0.457000	-0.457000	-2.00e-03	1.55e-03	9.89e-01
Vpu mediated degradation of CD4	49	6.74e-03	2.63e-02	0.262000	-0.260000	3.63e-02	1.65e-03	6.61e-01
RHOBTB GTPase Cycle	33	6.75e-03	2.63e-02	0.321000	-0.307000	9.46e-02	2.26e-03	3.47e-01
RHOB GTPase cycle	63	6.79e-03	2.64e-02	0.235000	-0.191000	1.36e-01	8.68e-03	6.25e-02
Processing of DNA double-strand break ends	62	6.83e-03	2.65e-02	0.228000	0.207000	9.57e-02	4.76e-03	1.93e-01
Kinesins	37	6.84e-03	2.65e-02	0.294000	0.203000	2.13e-01	3.28e-02	2.52e-02
Fcgamma receptor (FCGR) dependent phagocytosis	70	7.11e-03	2.74e-02	0.219000	-0.216000	3.73e-02	1.82e-03	5.90e-01
EPH-Ephrin signaling	80	7.31e-03	2.81e-02	0.204000	-0.201000	3.46e-02	1.87e-03	5.93e-01
Collagen biosynthesis and modifying enzymes	36	7.31e-03	2.81e-02	0.296000	0.196000	2.22e-01	4.16e-02	2.14e-02
Intraflagellar transport	34	7.40e-03	2.83e-02	0.309000	0.306000	3.85e-02	2.00e-03	6.98e-01
HIV Infection	217	7.46e-03	2.85e-02	0.123000	-0.123000	-2.74e-03	1.79e-03	9.45e-01
Mitotic Metaphase and Anaphase	222	7.54e-03	2.87e-02	0.120000	0.061500	1.03e-01	1.15e-01	8.38e-03
Pre-NOTCH Expression and Processing	46	7.79e-03	2.95e-02	0.269000	-0.095400	2.52e-01	2.63e-01	3.17e-03
The phototransduction cascade	21	8.16e-03	3.09e-02	0.388000	-0.056100	-3.84e-01	6.56e-01	2.30e-03
Signaling by EGFR in Cancer	22	8.21e-03	3.10e-02	0.383000	-0.381000	3.29e-02	1.96e-03	7.90e-01
Signaling by NOTCH1	62	8.35e-03	3.14e-02	0.228000	-0.227000	2.04e-02	2.00e-03	7.82e-01
Folding of actin by CCT/TriC	10	8.58e-03	3.22e-02	0.569000	-0.549000	1.47e-01	2.64e-03	4.20e-01
The role of GTSE1 in G2/M progression after G2 checkpoint	57	8.61e-03	3.22e-02	0.238000	-0.231000	5.84e-02	2.56e-03	4.46e-01
Organelle biogenesis and maintenance	243	8.62e-03	3.22e-02	0.113000	0.105000	4.40e-02	5.10e-03	2.39e-01
Signaling by Hedgehog	116	8.67e-03	3.23e-02	0.168000	-0.154000	6.72e-02	4.17e-03	2.12e-01
Regulation of lipid metabolism by PPARalpha	115	8.73e-03	3.24e-02	0.168000	-0.038400	1.63e-01	4.78e-01	2.51e-03
Defective pyroptosis	13	8.78e-03	3.25e-02	0.485000	0.428000	2.28e-01	7.60e-03	1.55e-01
Sphingolipid metabolism	77	9.46e-03	3.49e-02	0.205000	-0.170000	1.14e-01	9.83e-03	8.35e-02
Mitochondrial Fatty Acid Beta-Oxidation	32	9.62e-03	3.54e-02	0.305000	0.228000	2.02e-01	2.54e-02	4.76e-02
Olfactory Signaling Pathway	14	9.90e-03	3.63e-02	0.475000	0.184000	-4.38e-01	2.33e-01	4.51e-03
NGF-stimulated transcription	35	9.92e-03	3.63e-02	0.299000	-0.291000	7.08e-02	2.92e-03	4.69e-01
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	18	9.95e-03	3.64e-02	0.421000	-0.255000	3.35e-01	6.08e-02	1.39e-02
rRNA modification in the nucleus and cytosol	58	1.03e-02	3.74e-02	0.230000	-0.230000	1.14e-02	2.47e-03	8.80e-01
Suppression of phagosomal maturation	12	1.03e-02	3.74e-02	0.513000	-0.440000	2.64e-01	8.36e-03	1.13e-01
Initiation of Nuclear Envelope (NE) Reformation	19	1.03e-02	3.74e-02	0.402000	-0.051500	3.99e-01	6.98e-01	2.60e-03
Extra-nuclear estrogen signaling	57	1.04e-02	3.74e-02	0.230000	-0.226000	-4.25e-02	3.21e-03	5.79e-01
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	16	1.04e-02	3.74e-02	0.445000	-0.366000	2.52e-01	1.12e-02	8.12e-02
CDC42 GTPase cycle	130	1.04e-02	3.75e-02	0.156000	-0.130000	8.68e-02	1.05e-02	8.81e-02
FOXO-mediated transcription	52	1.06e-02	3.79e-02	0.246000	-0.208000	1.32e-01	9.66e-03	9.87e-02
Glycosphingolipid metabolism	39	1.07e-02	3.83e-02	0.283000	-0.125000	2.54e-01	1.76e-01	6.08e-03
PKA-mediated phosphorylation of CREB	14	1.08e-02	3.85e-02	0.468000	0.105000	-4.57e-01	4.98e-01	3.10e-03
Sialic acid metabolism	22	1.09e-02	3.88e-02	0.375000	-0.127000	3.53e-01	3.03e-01	4.19e-03
Programmed Cell Death	177	1.11e-02	3.92e-02	0.134000	-0.106000	8.14e-02	1.54e-02	6.22e-02
Synthesis of DNA	116	1.11e-02	3.92e-02	0.158000	0.105000	1.18e-01	5.08e-02	2.79e-02
Stabilization of p53	54	1.12e-02	3.97e-02	0.236000	-0.236000	1.48e-02	2.74e-03	8.51e-01
Metabolism of vitamins and cofactors	160	1.13e-02	3.97e-02	0.135000	0.113000	7.41e-02	1.40e-02	1.06e-01
Dissolution of Fibrin Clot	12	1.17e-02	4.11e-02	0.490000	0.180000	4.56e-01	2.81e-01	6.22e-03
Cyclin A/B1/B2 associated events during G2/M transition	24	1.18e-02	4.12e-02	0.345000	0.251000	2.36e-01	3.35e-02	4.52e-02
Metabolism of polyamines	56	1.19e-02	4.15e-02	0.231000	-0.229000	2.79e-02	3.00e-03	7.18e-01
PPARA activates gene expression	113	1.19e-02	4.15e-02	0.164000	-0.036500	1.59e-01	5.03e-01	3.44e-03
TP53 Regulates Transcription of Cell Death Genes	41	1.20e-02	4.19e-02	0.271000	-0.067500	2.62e-01	4.54e-01	3.68e-03
EGFR downregulation	26	1.23e-02	4.25e-02	0.337000	-0.336000	3.26e-02	3.06e-03	7.73e-01
Signaling by FGFR4	31	1.24e-02	4.28e-02	0.307000	-0.307000	2.30e-03	3.05e-03	9.82e-01
ERKs are inactivated	13	1.27e-02	4.39e-02	0.482000	-0.396000	2.75e-01	1.35e-02	8.61e-02
RHOA GTPase cycle	129	1.30e-02	4.49e-02	0.153000	-0.135000	7.21e-02	8.29e-03	1.58e-01
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	49	1.32e-02	4.50e-02	0.246000	-0.231000	8.59e-02	5.23e-03	2.99e-01
p53-Independent DNA Damage Response	49	1.32e-02	4.50e-02	0.246000	-0.231000	8.59e-02	5.23e-03	2.99e-01
p53-Independent G1/S DNA damage checkpoint	49	1.32e-02	4.50e-02	0.246000	-0.231000	8.59e-02	5.23e-03	2.99e-01
RHO GTPase Effectors	222	1.37e-02	4.68e-02	0.113000	0.022100	1.11e-01	5.72e-01	4.39e-03
Synthesis of PIPs at the plasma membrane	45	1.38e-02	4.70e-02	0.248000	-0.207000	-1.35e-01	1.61e-02	1.17e-01
RUNX3 regulates NOTCH signaling	12	1.41e-02	4.78e-02	0.493000	-0.187000	4.56e-01	2.62e-01	6.18e-03
Cargo recognition for clathrin-mediated endocytosis	81	1.44e-02	4.86e-02	0.188000	-0.187000	6.86e-03	3.58e-03	9.15e-01
Signaling by TGFB family members	87	1.45e-02	4.90e-02	0.181000	-0.180000	2.46e-02	3.78e-03	6.92e-01
CDT1 association with the CDC6:ORC:origin complex	56	1.47e-02	4.94e-02	0.227000	-0.218000	6.44e-02	4.88e-03	4.05e-01
TP53 Regulates Metabolic Genes	84	1.50e-02	5.05e-02	0.183000	-0.183000	2.39e-03	3.78e-03	9.70e-01
Removal of the Flap Intermediate from the C-strand	17	1.54e-02	5.17e-02	0.397000	0.324000	2.30e-01	2.08e-02	1.01e-01
Apoptotic cleavage of cellular proteins	31	1.56e-02	5.21e-02	0.304000	-0.133000	2.73e-01	2.01e-01	8.43e-03
Negative regulation of FGFR1 signaling	22	1.59e-02	5.31e-02	0.356000	-0.352000	5.29e-02	4.24e-03	6.68e-01
Basigin interactions	20	1.61e-02	5.35e-02	0.378000	-0.249000	2.85e-01	5.37e-02	2.75e-02
Antimicrobial peptides	17	1.62e-02	5.36e-02	0.394000	0.279000	2.79e-01	4.65e-02	4.66e-02
Signaling by FGFR3	32	1.62e-02	5.38e-02	0.291000	-0.288000	-4.63e-02	4.89e-03	6.50e-01
Separation of Sister Chromatids	165	1.63e-02	5.38e-02	0.127000	0.072600	1.04e-01	1.08e-01	2.08e-02
RHOD GTPase cycle	49	1.64e-02	5.39e-02	0.242000	-0.173000	1.68e-01	3.58e-02	4.18e-02
Condensation of Prometaphase Chromosomes	11	1.70e-02	5.59e-02	0.487000	0.341000	3.48e-01	5.03e-02	4.57e-02
Degradation of the extracellular matrix	61	1.74e-02	5.69e-02	0.213000	-0.050400	2.07e-01	4.96e-01	5.27e-03
G2/M Checkpoints	130	1.76e-02	5.76e-02	0.142000	0.104000	9.60e-02	4.06e-02	5.91e-02
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	68	1.84e-02	5.99e-02	0.200000	-0.195000	4.34e-02	5.41e-03	5.36e-01
Negative regulation of FGFR4 signaling	21	1.85e-02	6.01e-02	0.358000	-0.353000	6.24e-02	5.12e-03	6.21e-01
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	18	1.86e-02	6.03e-02	0.384000	-0.383000	-1.13e-02	4.86e-03	9.34e-01
Signaling by Ligand-Responsive EGFR Variants in Cancer	18	1.86e-02	6.03e-02	0.384000	-0.383000	-1.13e-02	4.86e-03	9.34e-01
Meiosis	46	1.88e-02	6.06e-02	0.236000	0.204000	1.20e-01	1.70e-02	1.60e-01
Post-translational modification: synthesis of GPI-anchored proteins	48	1.91e-02	6.17e-02	0.236000	0.233000	-3.55e-02	5.19e-03	6.70e-01
Cytosolic sensors of pathogen-associated DNA	53	2.06e-02	6.64e-02	0.223000	-0.220000	3.51e-02	5.67e-03	6.59e-01
RUNX3 regulates p14-ARF	10	2.12e-02	6.79e-02	0.513000	-0.485000	1.68e-01	7.93e-03	3.59e-01
ER-Phagosome pathway	79	2.12e-02	6.79e-02	0.184000	-0.155000	9.92e-02	1.73e-02	1.28e-01
p53-Dependent G1 DNA Damage Response	62	2.13e-02	6.80e-02	0.203000	-0.203000	-5.27e-03	5.64e-03	9.43e-01
p53-Dependent G1/S DNA damage checkpoint	62	2.13e-02	6.80e-02	0.203000	-0.203000	-5.27e-03	5.64e-03	9.43e-01
Inactivation of APC/C via direct inhibition of the APC/C complex	21	2.15e-02	6.82e-02	0.349000	0.349000	4.94e-03	5.65e-03	9.69e-01
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	21	2.15e-02	6.82e-02	0.349000	0.349000	4.94e-03	5.65e-03	9.69e-01
CD28 co-stimulation	26	2.16e-02	6.83e-02	0.310000	-0.289000	-1.10e-01	1.07e-02	3.32e-01
Regulation of signaling by CBL	14	2.16e-02	6.83e-02	0.425000	-0.421000	-5.82e-02	6.41e-03	7.06e-01
RND1 GTPase cycle	37	2.19e-02	6.91e-02	0.268000	-0.206000	1.71e-01	2.99e-02	7.27e-02
Attenuation phase	21	2.21e-02	6.96e-02	0.351000	-0.338000	9.47e-02	7.27e-03	4.53e-01
Mitochondrial tRNA aminoacylation	18	2.24e-02	7.03e-02	0.382000	0.330000	-1.92e-01	1.54e-02	1.58e-01
RHOBTB2 GTPase cycle	23	2.37e-02	7.43e-02	0.332000	-0.326000	6.25e-02	6.85e-03	6.04e-01
Signaling by Nuclear Receptors	197	2.41e-02	7.51e-02	0.115000	-0.099800	5.70e-02	1.59e-02	1.68e-01
HDACs deacetylate histones	32	2.41e-02	7.51e-02	0.274000	-0.234000	-1.42e-01	2.21e-02	1.63e-01
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	24	2.54e-02	7.88e-02	0.314000	0.264000	1.69e-01	2.50e-02	1.52e-01
Activation of NMDA receptors and postsynaptic events	56	2.56e-02	7.94e-02	0.210000	0.016500	-2.09e-01	8.31e-01	6.82e-03
RET signaling	34	2.62e-02	8.11e-02	0.264000	-0.254000	-7.47e-02	1.05e-02	4.51e-01
Antigen processing: Ubiquitination & Proteasome degradation	279	2.64e-02	8.15e-02	0.093700	-0.093400	-7.39e-03	7.42e-03	8.32e-01
Nephrin family interactions	17	2.66e-02	8.17e-02	0.380000	-0.374000	6.79e-02	7.65e-03	6.28e-01
DARPP-32 events	20	2.66e-02	8.17e-02	0.341000	-0.280000	-1.95e-01	3.01e-02	1.31e-01
Intra-Golgi traffic	40	2.72e-02	8.33e-02	0.245000	-0.245000	-2.44e-03	7.32e-03	9.79e-01
Extracellular matrix organization	183	2.72e-02	8.33e-02	0.113000	0.066500	9.15e-02	1.22e-01	3.32e-02
RIP-mediated NFkB activation via ZBP1	14	2.76e-02	8.44e-02	0.416000	-0.411000	6.36e-02	7.78e-03	6.80e-01
tRNA processing in the mitochondrion	17	2.78e-02	8.47e-02	0.369000	0.325000	1.74e-01	2.04e-02	2.14e-01
G1/S-Specific Transcription	28	2.79e-02	8.47e-02	0.287000	0.243000	1.53e-01	2.62e-02	1.62e-01
Plasma lipoprotein assembly, remodeling, and clearance	64	2.80e-02	8.47e-02	0.195000	-0.054500	1.88e-01	4.51e-01	9.50e-03
Semaphorin interactions	51	2.81e-02	8.47e-02	0.220000	-0.198000	9.50e-02	1.44e-02	2.41e-01
Transcriptional Regulation by TP53	351	2.81e-02	8.47e-02	0.085000	-0.067200	5.19e-02	3.11e-02	9.60e-02
ERK/MAPK targets	21	2.81e-02	8.47e-02	0.340000	-0.327000	9.50e-02	9.53e-03	4.51e-01
Neurotransmitter receptors and postsynaptic signal transmission	108	2.83e-02	8.51e-02	0.150000	0.023800	-1.48e-01	6.69e-01	8.03e-03
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	38	2.86e-02	8.58e-02	0.246000	0.098100	2.26e-01	2.96e-01	1.60e-02
tRNA Aminoacylation	24	2.87e-02	8.60e-02	0.320000	0.229000	-2.24e-01	5.18e-02	5.79e-02
DNA Replication Pre-Initiation	85	2.88e-02	8.60e-02	0.167000	-0.009310	1.67e-01	8.82e-01	7.75e-03
Tie2 Signaling	14	2.88e-02	8.60e-02	0.404000	-0.355000	-1.92e-01	2.13e-02	2.13e-01
Prolonged ERK activation events	12	2.90e-02	8.61e-02	0.451000	-0.390000	2.27e-01	1.93e-02	1.74e-01
Asymmetric localization of PCP proteins	58	2.90e-02	8.61e-02	0.205000	-0.192000	7.02e-02	1.14e-02	3.55e-01
Metabolism of nucleotides	86	2.93e-02	8.67e-02	0.163000	0.117000	1.13e-01	6.19e-02	6.95e-02
Glyoxylate metabolism and glycine degradation	27	2.95e-02	8.69e-02	0.299000	0.279000	-1.08e-01	1.22e-02	3.31e-01
SCF(Skp2)-mediated degradation of p27/p21	58	2.95e-02	8.69e-02	0.202000	-0.202000	3.29e-03	7.96e-03	9.66e-01
Binding and Uptake of Ligands by Scavenger Receptors	27	2.96e-02	8.69e-02	0.300000	-0.167000	2.50e-01	1.34e-01	2.46e-02
FCGR3A-mediated phagocytosis	47	2.97e-02	8.69e-02	0.223000	-0.223000	-4.69e-03	8.13e-03	9.56e-01
Leishmania phagocytosis	47	2.97e-02	8.69e-02	0.223000	-0.223000	-4.69e-03	8.13e-03	9.56e-01
Parasite infection	47	2.97e-02	8.69e-02	0.223000	-0.223000	-4.69e-03	8.13e-03	9.56e-01
Carboxyterminal post-translational modifications of tubulin	30	2.99e-02	8.72e-02	0.279000	0.279000	1.28e-03	8.12e-03	9.90e-01
Signaling by FGFR	69	3.00e-02	8.72e-02	0.187000	-0.177000	5.83e-02	1.09e-02	4.03e-01
Activated NOTCH1 Transmits Signal to the Nucleus	25	3.01e-02	8.75e-02	0.307000	-0.305000	3.07e-02	8.25e-03	7.90e-01
Constitutive Signaling by AKT1 E17K in Cancer	24	3.02e-02	8.75e-02	0.308000	-0.291000	-1.00e-01	1.35e-02	3.95e-01
Interconversion of nucleotide di- and triphosphates	27	3.03e-02	8.75e-02	0.293000	0.013300	2.93e-01	9.05e-01	8.40e-03
Plasma lipoprotein clearance	32	3.04e-02	8.77e-02	0.275000	-0.202000	1.88e-01	4.84e-02	6.64e-02
Metabolism of water-soluble vitamins and cofactors	104	3.06e-02	8.81e-02	0.148000	0.130000	6.97e-02	2.21e-02	2.20e-01
Mitotic Prophase	81	3.09e-02	8.88e-02	0.170000	-0.002370	1.70e-01	9.71e-01	8.38e-03
Insulin receptor signalling cascade	37	3.12e-02	8.96e-02	0.251000	-0.249000	3.51e-02	8.80e-03	7.12e-01
Polo-like kinase mediated events	16	3.16e-02	9.06e-02	0.372000	0.309000	2.08e-01	3.26e-02	1.49e-01
Signaling by MET	63	3.25e-02	9.30e-02	0.189000	-0.182000	-4.92e-02	1.24e-02	4.99e-01
Effects of PIP2 hydrolysis	18	3.30e-02	9.40e-02	0.361000	-0.325000	1.57e-01	1.69e-02	2.50e-01
Glutamate and glutamine metabolism	11	3.34e-02	9.51e-02	0.450000	0.104000	4.37e-01	5.50e-01	1.20e-02
Signaling by NOTCH3	37	3.51e-02	9.96e-02	0.251000	-0.202000	1.48e-01	3.33e-02	1.19e-01
Signaling by FGFR1	38	3.52e-02	9.98e-02	0.243000	-0.243000	1.17e-02	9.69e-03	9.01e-01
Incretin synthesis, secretion, and inactivation	13	3.53e-02	9.99e-02	0.417000	-0.407000	9.22e-02	1.10e-02	5.65e-01
Estrogen-dependent gene expression	84	3.54e-02	9.99e-02	0.167000	-0.120000	1.16e-01	5.80e-02	6.70e-02
Regulation of PLK1 Activity at G2/M Transition	84	3.56e-02	1.00e-01	0.164000	0.163000	-1.61e-02	9.91e-03	7.99e-01
NOTCH3 Intracellular Domain Regulates Transcription	17	3.56e-02	1.00e-01	0.366000	-0.120000	3.46e-01	3.91e-01	1.36e-02
Negative regulation of MET activity	18	3.60e-02	1.01e-01	0.355000	-0.340000	1.01e-01	1.25e-02	4.57e-01
Nicotinate metabolism	23	3.61e-02	1.01e-01	0.316000	0.271000	-1.63e-01	2.46e-02	1.77e-01
Post-chaperonin tubulin folding pathway	17	3.62e-02	1.01e-01	0.366000	0.341000	-1.31e-01	1.49e-02	3.50e-01
TNFs bind their physiological receptors	11	3.65e-02	1.02e-01	0.447000	-0.028100	-4.46e-01	8.72e-01	1.05e-02
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	10	3.66e-02	1.02e-01	0.477000	-0.420000	2.26e-01	2.13e-02	2.16e-01
NF-kB is activated and signals survival	12	3.80e-02	1.05e-01	0.424000	-0.422000	-4.52e-02	1.14e-02	7.86e-01
TRAF6 mediated NF-kB activation	22	3.89e-02	1.08e-01	0.314000	-0.314000	1.66e-02	1.08e-02	8.93e-01
FLT3 Signaling	32	3.98e-02	1.10e-01	0.261000	-0.255000	5.82e-02	1.26e-02	5.69e-01
MET activates RAS signaling	10	4.07e-02	1.12e-01	0.464000	-0.461000	4.48e-02	1.15e-02	8.06e-01
DAP12 signaling	21	4.13e-02	1.14e-01	0.313000	-0.284000	-1.31e-01	2.41e-02	2.97e-01
Defective B3GALTL causes PpS	19	4.17e-02	1.15e-01	0.328000	0.184000	2.71e-01	1.64e-01	4.09e-02
RHOH GTPase cycle	32	4.20e-02	1.15e-01	0.260000	-0.247000	8.34e-02	1.58e-02	4.15e-01
E2F mediated regulation of DNA replication	22	4.24e-02	1.16e-01	0.305000	0.272000	1.37e-01	2.72e-02	2.66e-01
ZBP1(DAI) mediated induction of type I IFNs	17	4.28e-02	1.17e-01	0.353000	-0.352000	2.55e-02	1.21e-02	8.56e-01
mTORC1-mediated signalling	24	4.33e-02	1.18e-01	0.299000	-0.284000	9.23e-02	1.60e-02	4.34e-01
Negative regulation of FGFR3 signaling	21	4.33e-02	1.18e-01	0.315000	-0.315000	-8.28e-03	1.24e-02	9.48e-01
Spry regulation of FGF signaling	16	4.34e-02	1.18e-01	0.365000	-0.352000	9.81e-02	1.48e-02	4.97e-01
Death Receptor Signalling	124	4.47e-02	1.20e-01	0.130000	-0.130000	-8.28e-05	1.27e-02	9.99e-01
Activation of BAD and translocation to mitochondria	14	4.48e-02	1.20e-01	0.377000	-0.291000	-2.40e-01	5.98e-02	1.20e-01
CD28 dependent PI3K/Akt signaling	18	4.50e-02	1.20e-01	0.338000	-0.337000	-1.96e-02	1.32e-02	8.86e-01
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	49	4.51e-02	1.20e-01	0.204000	-0.200000	-4.02e-02	1.55e-02	6.26e-01
Constitutive Signaling by NOTCH1 PEST Domain Mutants	49	4.51e-02	1.20e-01	0.204000	-0.200000	-4.02e-02	1.55e-02	6.26e-01
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	49	4.51e-02	1.20e-01	0.204000	-0.200000	-4.02e-02	1.55e-02	6.26e-01
Signaling by NOTCH1 PEST Domain Mutants in Cancer	49	4.51e-02	1.20e-01	0.204000	-0.200000	-4.02e-02	1.55e-02	6.26e-01
Signaling by NOTCH1 in Cancer	49	4.51e-02	1.20e-01	0.204000	-0.200000	-4.02e-02	1.55e-02	6.26e-01
rRNA processing in the mitochondrion	21	4.52e-02	1.20e-01	0.311000	0.306000	5.80e-02	1.53e-02	6.45e-01
Signaling by ALK fusions and activated point mutants	50	4.53e-02	1.20e-01	0.205000	-0.201000	3.74e-02	1.38e-02	6.48e-01
Signaling by ALK in cancer	50	4.53e-02	1.20e-01	0.205000	-0.201000	3.74e-02	1.38e-02	6.48e-01
Acyl chain remodelling of PC	11	4.66e-02	1.24e-01	0.423000	0.286000	3.11e-01	1.00e-01	7.41e-02
p75 NTR receptor-mediated signalling	82	4.71e-02	1.25e-01	0.158000	-0.158000	5.84e-03	1.34e-02	9.27e-01
SHC1 events in EGFR signaling	11	4.77e-02	1.26e-01	0.434000	-0.416000	1.26e-01	1.70e-02	4.71e-01
Cleavage of the damaged purine	11	4.81e-02	1.26e-01	0.421000	0.357000	2.23e-01	4.01e-02	2.00e-01
Depurination	11	4.81e-02	1.26e-01	0.421000	0.357000	2.23e-01	4.01e-02	2.00e-01
Recognition and association of DNA glycosylase with site containing an affected purine	11	4.81e-02	1.26e-01	0.421000	0.357000	2.23e-01	4.01e-02	2.00e-01
Regulation of PTEN mRNA translation	12	4.92e-02	1.29e-01	0.414000	-0.135000	3.91e-01	4.17e-01	1.89e-02
HSF1-dependent transactivation	30	4.99e-02	1.31e-01	0.259000	-0.258000	1.62e-02	1.44e-02	8.78e-01
Constitutive Signaling by Aberrant PI3K in Cancer	43	5.01e-02	1.31e-01	0.217000	-0.212000	4.72e-02	1.61e-02	5.92e-01
Degradation of cysteine and homocysteine	12	5.07e-02	1.32e-01	0.409000	0.405000	-5.75e-02	1.51e-02	7.30e-01
Constitutive Signaling by EGFRvIII	14	5.09e-02	1.32e-01	0.377000	-0.377000	5.41e-03	1.47e-02	9.72e-01
Signaling by EGFRvIII in Cancer	14	5.09e-02	1.32e-01	0.377000	-0.377000	5.41e-03	1.47e-02	9.72e-01
Neddylation	214	5.12e-02	1.33e-01	0.096000	-0.093200	-2.29e-02	1.91e-02	5.65e-01
Regulation of PTEN gene transcription	58	5.13e-02	1.33e-01	0.185000	-0.185000	3.69e-03	1.48e-02	9.61e-01
Assembly of the pre-replicative complex	69	5.16e-02	1.33e-01	0.173000	-0.105000	1.37e-01	1.32e-01	4.86e-02
Negative regulation of FLT3	13	5.23e-02	1.35e-01	0.397000	-0.320000	2.34e-01	4.58e-02	1.44e-01
RAF activation	33	5.23e-02	1.35e-01	0.244000	-0.244000	-6.55e-03	1.54e-02	9.48e-01
PKA activation	12	5.25e-02	1.35e-01	0.409000	0.126000	-3.89e-01	4.51e-01	1.95e-02
G1/S DNA Damage Checkpoints	64	5.30e-02	1.36e-01	0.175000	-0.175000	5.89e-03	1.54e-02	9.35e-01
Role of LAT2/NTAL/LAB on calcium mobilization	12	5.36e-02	1.37e-01	0.396000	-0.317000	-2.36e-01	5.70e-02	1.57e-01
FCERI mediated MAPK activation	25	5.38e-02	1.38e-01	0.279000	-0.279000	-6.46e-03	1.58e-02	9.55e-01
Signalling to RAS	18	5.45e-02	1.39e-01	0.331000	-0.325000	6.12e-02	1.70e-02	6.53e-01
RHOBTB1 GTPase cycle	21	5.46e-02	1.39e-01	0.305000	-0.304000	2.94e-02	1.60e-02	8.16e-01
FCGR3A-mediated IL10 synthesis	23	5.48e-02	1.39e-01	0.291000	0.022800	-2.90e-01	8.50e-01	1.60e-02
Signaling by PDGF	44	5.51e-02	1.40e-01	0.209000	0.021700	2.08e-01	8.04e-01	1.72e-02
Signaling by FGFR2	57	5.58e-02	1.41e-01	0.186000	-0.175000	6.42e-02	2.24e-02	4.02e-01
RORA activates gene expression	18	5.60e-02	1.42e-01	0.333000	-0.229000	2.43e-01	9.32e-02	7.48e-02
PKA activation in glucagon signalling	11	5.61e-02	1.42e-01	0.422000	0.119000	-4.05e-01	4.96e-01	2.00e-02
Gap junction trafficking and regulation	14	5.67e-02	1.43e-01	0.370000	-0.015300	3.70e-01	9.21e-01	1.66e-02
TAK1 activates NFkB by phosphorylation and activation of IKKs complex	24	5.75e-02	1.44e-01	0.286000	-0.254000	1.31e-01	3.10e-02	2.66e-01
Transport of bile salts and organic acids, metal ions and amine compounds	58	5.76e-02	1.44e-01	0.185000	-0.104000	1.53e-01	1.70e-01	4.45e-02
Gap-filling DNA repair synthesis and ligation in GG-NER	25	5.76e-02	1.44e-01	0.271000	0.201000	1.81e-01	8.18e-02	1.17e-01
Inhibition of replication initiation of damaged DNA by RB1/E2F1	13	5.78e-02	1.45e-01	0.375000	0.217000	3.06e-01	1.76e-01	5.60e-02
Translation of Structural Proteins	27	5.83e-02	1.45e-01	0.270000	-0.227000	1.46e-01	4.15e-02	1.88e-01
Nuclear Envelope Breakdown	51	5.85e-02	1.46e-01	0.190000	0.063100	1.80e-01	4.36e-01	2.65e-02
MTOR signalling	40	5.89e-02	1.46e-01	0.218000	-0.217000	1.56e-02	1.74e-02	8.64e-01
Synthesis of PA	25	5.92e-02	1.47e-01	0.269000	0.201000	1.79e-01	8.13e-02	1.22e-01
Cyclin E associated events during G1/S transition	80	5.94e-02	1.47e-01	0.153000	-0.152000	-1.57e-02	1.87e-02	8.08e-01
Signaling by high-kinase activity BRAF mutants	30	5.96e-02	1.47e-01	0.255000	-0.151000	2.06e-01	1.52e-01	5.13e-02
Gap junction trafficking	12	6.02e-02	1.48e-01	0.395000	-0.005450	3.95e-01	9.74e-01	1.78e-02
Ovarian tumor domain proteases	36	6.06e-02	1.49e-01	0.229000	-0.228000	2.27e-02	1.81e-02	8.14e-01
Translocation of SLC2A4 (GLUT4) to the plasma membrane	50	6.21e-02	1.53e-01	0.190000	-0.072600	-1.76e-01	3.75e-01	3.18e-02
Phosphorylation of the APC/C	20	6.24e-02	1.53e-01	0.306000	0.302000	-4.71e-02	1.93e-02	7.16e-01
Metabolism of carbohydrates	235	6.32e-02	1.55e-01	0.088500	0.018200	8.66e-02	6.32e-01	2.26e-02
Intrinsic Pathway of Fibrin Clot Formation	18	6.34e-02	1.55e-01	0.314000	0.258000	1.78e-01	5.80e-02	1.90e-01
PCNA-Dependent Long Patch Base Excision Repair	21	6.35e-02	1.55e-01	0.290000	0.225000	1.83e-01	7.41e-02	1.47e-01
Cohesin Loading onto Chromatin	10	6.36e-02	1.55e-01	0.425000	-0.082400	-4.17e-01	6.52e-01	2.24e-02
Regulation of BACH1 activity	11	6.38e-02	1.55e-01	0.413000	-0.393000	1.27e-01	2.40e-02	4.67e-01
Miscellaneous transport and binding events	21	6.39e-02	1.55e-01	0.301000	-0.248000	1.71e-01	4.90e-02	1.76e-01
Diseases of mitotic cell cycle	37	6.48e-02	1.57e-01	0.226000	0.197000	-1.10e-01	3.79e-02	2.46e-01
Sphingolipid de novo biosynthesis	38	6.52e-02	1.58e-01	0.218000	-0.216000	-2.98e-02	2.14e-02	7.50e-01
p75NTR signals via NF-kB	15	6.61e-02	1.60e-01	0.347000	-0.347000	-5.46e-03	2.00e-02	9.71e-01
Mitophagy	27	6.62e-02	1.60e-01	0.263000	-0.241000	1.04e-01	3.00e-02	3.50e-01
Formation of RNA Pol II elongation complex	57	6.66e-02	1.60e-01	0.177000	-0.173000	-3.67e-02	2.40e-02	6.32e-01
RNA Polymerase II Transcription Elongation	57	6.66e-02	1.60e-01	0.177000	-0.173000	-3.67e-02	2.40e-02	6.32e-01
DNA Damage Bypass	47	6.74e-02	1.62e-01	0.194000	0.044300	1.89e-01	6.00e-01	2.51e-02
FRS-mediated FGFR3 signaling	12	6.75e-02	1.62e-01	0.380000	-0.184000	-3.33e-01	2.69e-01	4.58e-02
Cell recruitment (pro-inflammatory response)	19	6.79e-02	1.62e-01	0.302000	0.257000	1.59e-01	5.28e-02	2.31e-01
Purinergic signaling in leishmaniasis infection	19	6.79e-02	1.62e-01	0.302000	0.257000	1.59e-01	5.28e-02	2.31e-01
RAF-independent MAPK1/3 activation	21	6.79e-02	1.62e-01	0.298000	-0.222000	1.99e-01	7.79e-02	1.15e-01
Cytosolic sulfonation of small molecules	20	6.79e-02	1.62e-01	0.294000	0.255000	1.46e-01	4.81e-02	2.57e-01
HDR through MMEJ (alt-NHEJ)	10	6.82e-02	1.62e-01	0.421000	0.417000	5.43e-02	2.23e-02	7.66e-01
Methylation	12	6.93e-02	1.64e-01	0.381000	0.365000	1.09e-01	2.86e-02	5.14e-01
RHOU GTPase cycle	36	6.94e-02	1.64e-01	0.226000	-0.198000	1.09e-01	3.97e-02	2.57e-01
Rab regulation of trafficking	114	7.03e-02	1.66e-01	0.125000	-0.125000	1.15e-02	2.14e-02	8.32e-01
EGR2 and SOX10-mediated initiation of Schwann cell myelination	23	7.03e-02	1.66e-01	0.274000	0.255000	9.85e-02	3.40e-02	4.14e-01
Glycolysis	65	7.05e-02	1.66e-01	0.168000	-0.086700	1.44e-01	2.27e-01	4.46e-02
SUMOylation of transcription factors	16	7.09e-02	1.67e-01	0.332000	0.005010	-3.32e-01	9.72e-01	2.15e-02
GPCR ligand binding	128	7.10e-02	1.67e-01	0.116000	0.086200	7.69e-02	9.25e-02	1.34e-01
EPHB-mediated forward signaling	34	7.11e-02	1.67e-01	0.225000	-0.210000	-7.91e-02	3.38e-02	4.25e-01
NOTCH1 Intracellular Domain Regulates Transcription	42	7.17e-02	1.67e-01	0.205000	-0.205000	8.40e-03	2.17e-02	9.25e-01
Costimulation by the CD28 family	41	7.17e-02	1.67e-01	0.206000	-0.204000	-2.65e-02	2.36e-02	7.69e-01
L1CAM interactions	72	7.22e-02	1.68e-01	0.159000	-0.145000	6.39e-02	3.33e-02	3.49e-01
Signaling by NTRK2 (TRKB)	20	7.25e-02	1.69e-01	0.292000	-0.096700	-2.76e-01	4.54e-01	3.29e-02
Competing endogenous RNAs (ceRNAs) regulate PTEN translation	11	7.27e-02	1.69e-01	0.402000	-0.086900	3.92e-01	6.18e-01	2.43e-02
Aberrant regulation of mitotic exit in cancer due to RB1 defects	20	7.28e-02	1.69e-01	0.300000	0.269000	-1.34e-01	3.74e-02	3.01e-01
TICAM1-dependent activation of IRF3/IRF7	10	7.28e-02	1.69e-01	0.410000	-0.338000	-2.32e-01	6.40e-02	2.04e-01
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	20	7.30e-02	1.69e-01	0.300000	0.264000	-1.42e-01	4.06e-02	2.70e-01
Formation of TC-NER Pre-Incision Complex	53	7.34e-02	1.69e-01	0.179000	-0.172000	-5.20e-02	3.06e-02	5.12e-01
Downstream signaling of activated FGFR3	17	7.35e-02	1.69e-01	0.314000	-0.216000	-2.27e-01	1.23e-01	1.04e-01
Nicotinamide salvaging	14	7.37e-02	1.69e-01	0.356000	0.341000	-1.05e-01	2.74e-02	4.98e-01
CaM pathway	24	7.40e-02	1.70e-01	0.272000	0.074000	-2.62e-01	5.30e-01	2.66e-02
Calmodulin induced events	24	7.40e-02	1.70e-01	0.272000	0.074000	-2.62e-01	5.30e-01	2.66e-02
APC truncation mutants have impaired AXIN binding	14	7.56e-02	1.72e-01	0.356000	-0.324000	1.47e-01	3.57e-02	3.42e-01
AXIN missense mutants destabilize the destruction complex	14	7.56e-02	1.72e-01	0.356000	-0.324000	1.47e-01	3.57e-02	3.42e-01
Signaling by AMER1 mutants	14	7.56e-02	1.72e-01	0.356000	-0.324000	1.47e-01	3.57e-02	3.42e-01
Signaling by APC mutants	14	7.56e-02	1.72e-01	0.356000	-0.324000	1.47e-01	3.57e-02	3.42e-01
Signaling by AXIN mutants	14	7.56e-02	1.72e-01	0.356000	-0.324000	1.47e-01	3.57e-02	3.42e-01
Truncations of AMER1 destabilize the destruction complex	14	7.56e-02	1.72e-01	0.356000	-0.324000	1.47e-01	3.57e-02	3.42e-01
Pausing and recovery of Tat-mediated HIV elongation	30	7.61e-02	1.72e-01	0.239000	-0.239000	-2.81e-03	2.34e-02	9.79e-01
Tat-mediated HIV elongation arrest and recovery	30	7.61e-02	1.72e-01	0.239000	-0.239000	-2.81e-03	2.34e-02	9.79e-01
Regulation of TP53 Activity through Phosphorylation	88	8.02e-02	1.81e-01	0.139000	0.139000	-1.23e-02	2.48e-02	8.43e-01
FOXO-mediated transcription of cell death genes	15	8.13e-02	1.83e-01	0.340000	-0.286000	1.83e-01	5.49e-02	2.19e-01
Vitamin B5 (pantothenate) metabolism	16	8.18e-02	1.84e-01	0.317000	0.270000	1.67e-01	6.20e-02	2.47e-01
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	20	8.26e-02	1.86e-01	0.287000	-0.286000	-2.37e-02	2.66e-02	8.55e-01
COPI-independent Golgi-to-ER retrograde traffic	31	8.29e-02	1.86e-01	0.229000	-0.071300	-2.17e-01	4.92e-01	3.62e-02
IRS-mediated signalling	32	8.38e-02	1.88e-01	0.225000	-0.216000	-6.13e-02	3.41e-02	5.49e-01
Pre-NOTCH Transcription and Translation	31	8.43e-02	1.88e-01	0.232000	-0.022200	2.31e-01	8.31e-01	2.64e-02
Post NMDA receptor activation events	47	8.58e-02	1.91e-01	0.187000	-0.006790	-1.86e-01	9.36e-01	2.71e-02
Growth hormone receptor signaling	20	8.62e-02	1.92e-01	0.282000	0.116000	2.56e-01	3.67e-01	4.71e-02
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	12	8.88e-02	1.97e-01	0.368000	-0.367000	3.06e-02	2.79e-02	8.54e-01
Signaling by ERBB2	42	8.88e-02	1.97e-01	0.197000	-0.196000	2.29e-02	2.82e-02	7.97e-01
Retrograde neurotrophin signalling	10	8.90e-02	1.97e-01	0.409000	-0.250000	3.24e-01	1.70e-01	7.62e-02
Selective autophagy	56	8.93e-02	1.98e-01	0.171000	-0.169000	2.16e-02	2.85e-02	7.80e-01
Activation of Matrix Metalloproteinases	15	8.99e-02	1.99e-01	0.325000	0.066100	3.18e-01	6.57e-01	3.32e-02
Cyclin A:Cdk2-associated events at S phase entry	82	9.03e-02	1.99e-01	0.139000	-0.138000	-1.90e-02	3.09e-02	7.66e-01
PI-3K cascade:FGFR3	10	9.04e-02	1.99e-01	0.393000	-0.238000	-3.12e-01	1.92e-01	8.75e-02
HATs acetylate histones	78	9.05e-02	1.99e-01	0.145000	-0.138000	4.67e-02	3.57e-02	4.76e-01
Mitotic G1 phase and G1/S transition	144	9.12e-02	2.00e-01	0.104000	0.034900	9.84e-02	4.70e-01	4.18e-02
Metal ion SLC transporters	23	9.16e-02	2.01e-01	0.266000	-0.058700	2.59e-01	6.26e-01	3.16e-02
APC-Cdc20 mediated degradation of Nek2A	26	9.17e-02	2.01e-01	0.247000	0.247000	8.49e-03	2.93e-02	9.40e-01
Golgi-to-ER retrograde transport	106	9.21e-02	2.01e-01	0.125000	-0.097000	7.93e-02	8.47e-02	1.59e-01
Signaling by ERBB4	42	9.33e-02	2.03e-01	0.191000	-0.167000	-9.20e-02	6.06e-02	3.03e-01
Signaling by FGFR3 in disease	14	9.36e-02	2.03e-01	0.329000	-0.203000	-2.59e-01	1.89e-01	9.28e-02
Signaling by FGFR3 point mutants in cancer	14	9.36e-02	2.03e-01	0.329000	-0.203000	-2.59e-01	1.89e-01	9.28e-02
Constitutive Signaling by NOTCH1 HD Domain Mutants	12	9.39e-02	2.03e-01	0.363000	-0.363000	1.05e-02	2.96e-02	9.50e-01
Signaling by NOTCH1 HD Domain Mutants in Cancer	12	9.39e-02	2.03e-01	0.363000	-0.363000	1.05e-02	2.96e-02	9.50e-01
G0 and Early G1	26	9.40e-02	2.03e-01	0.242000	0.177000	1.65e-01	1.19e-01	1.46e-01
S Phase	157	9.48e-02	2.05e-01	0.098700	0.080400	5.72e-02	8.27e-02	2.17e-01
Transcriptional regulation of granulopoiesis	25	9.52e-02	2.06e-01	0.255000	-0.135000	2.16e-01	2.42e-01	6.12e-02
GABA synthesis, release, reuptake and degradation	11	9.56e-02	2.06e-01	0.385000	-0.253000	2.90e-01	1.47e-01	9.55e-02
Downstream signaling of activated FGFR4	17	9.67e-02	2.08e-01	0.298000	-0.263000	-1.40e-01	6.08e-02	3.17e-01
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	24	9.76e-02	2.10e-01	0.254000	0.000465	-2.54e-01	9.97e-01	3.11e-02
O-glycosylation of TSR domain-containing proteins	20	9.85e-02	2.11e-01	0.273000	0.172000	2.11e-01	1.82e-01	1.02e-01
DDX58/IFIH1-mediated induction of interferon-alpha/beta	64	9.92e-02	2.12e-01	0.158000	-0.142000	6.97e-02	5.02e-02	3.35e-01
Aberrant regulation of mitotic cell cycle due to RB1 defects	35	9.97e-02	2.13e-01	0.213000	0.185000	-1.06e-01	5.81e-02	2.78e-01
Pre-NOTCH Processing in Golgi	16	1.00e-01	2.14e-01	0.315000	-0.156000	2.74e-01	2.81e-01	5.81e-02
Synthesis of PIPs at the early endosome membrane	15	1.01e-01	2.15e-01	0.313000	-0.254000	-1.83e-01	8.82e-02	2.19e-01
Diseases of glycosylation	99	1.01e-01	2.16e-01	0.124000	0.017300	1.23e-01	7.67e-01	3.52e-02
IGF1R signaling cascade	35	1.02e-01	2.16e-01	0.208000	-0.208000	-6.32e-03	3.29e-02	9.48e-01
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	35	1.02e-01	2.16e-01	0.208000	-0.208000	-6.32e-03	3.29e-02	9.48e-01
Mitochondrial translation	93	1.04e-01	2.20e-01	0.125000	-0.072600	-1.02e-01	2.27e-01	8.87e-02
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins	10	1.04e-01	2.21e-01	0.381000	0.313000	2.18e-01	8.67e-02	2.34e-01
tRNA modification in the nucleus and cytosol	41	1.05e-01	2.22e-01	0.195000	0.089900	-1.73e-01	3.19e-01	5.58e-02
Negative regulation of FGFR2 signaling	21	1.05e-01	2.22e-01	0.270000	-0.263000	6.14e-02	3.72e-02	6.26e-01
HSF1 activation	24	1.05e-01	2.22e-01	0.255000	-0.211000	1.42e-01	7.33e-02	2.27e-01
TICAM1, RIP1-mediated IKK complex recruitment	17	1.08e-01	2.26e-01	0.290000	-0.244000	-1.58e-01	8.17e-02	2.61e-01
Signaling by PDGFR in disease	17	1.08e-01	2.27e-01	0.294000	-0.291000	-3.84e-02	3.76e-02	7.84e-01
HIV elongation arrest and recovery	32	1.11e-01	2.31e-01	0.213000	-0.212000	-2.20e-02	3.78e-02	8.30e-01
Pausing and recovery of HIV elongation	32	1.11e-01	2.31e-01	0.213000	-0.212000	-2.20e-02	3.78e-02	8.30e-01
Defective EXT1 causes exostoses 1, TRPS2 and CHDS	13	1.11e-01	2.31e-01	0.338000	0.334000	-5.09e-02	3.71e-02	7.51e-01
Defective EXT2 causes exostoses 2	13	1.11e-01	2.31e-01	0.338000	0.334000	-5.09e-02	3.71e-02	7.51e-01
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	13	1.12e-01	2.32e-01	0.336000	-0.018500	3.36e-01	9.08e-01	3.62e-02
Translesion Synthesis by POLH	18	1.12e-01	2.33e-01	0.280000	0.129000	2.49e-01	3.45e-01	6.74e-02
SUMOylation of intracellular receptors	25	1.12e-01	2.33e-01	0.240000	-0.237000	-3.60e-02	3.99e-02	7.55e-01
Reproduction	56	1.13e-01	2.35e-01	0.160000	0.153000	4.39e-02	4.72e-02	5.70e-01
Synthesis of very long-chain fatty acyl-CoAs	18	1.15e-01	2.38e-01	0.279000	0.106000	2.58e-01	4.37e-01	5.77e-02
SHC1 events in ERBB2 signaling	15	1.15e-01	2.38e-01	0.316000	-0.262000	1.76e-01	7.86e-02	2.38e-01
RHO GTPases Activate WASPs and WAVEs	32	1.15e-01	2.38e-01	0.213000	-0.212000	8.71e-03	3.76e-02	9.32e-01
Phospholipid metabolism	160	1.16e-01	2.38e-01	0.095600	-0.095200	9.12e-03	3.81e-02	8.42e-01
Trafficking and processing of endosomal TLR	10	1.16e-01	2.39e-01	0.379000	-0.379000	1.13e-02	3.80e-02	9.51e-01
MAP2K and MAPK activation	34	1.17e-01	2.40e-01	0.210000	-0.143000	1.53e-01	1.48e-01	1.23e-01
Sulfur amino acid metabolism	26	1.17e-01	2.41e-01	0.235000	0.234000	-2.17e-02	3.87e-02	8.48e-01
Vasopressin regulates renal water homeostasis via Aquaporins	24	1.18e-01	2.43e-01	0.248000	0.116000	-2.19e-01	3.25e-01	6.37e-02
GPVI-mediated activation cascade	22	1.20e-01	2.45e-01	0.250000	-0.231000	-9.50e-02	6.03e-02	4.41e-01
Energy dependent regulation of mTOR by LKB1-AMPK	28	1.20e-01	2.45e-01	0.223000	-0.216000	-5.61e-02	4.85e-02	6.08e-01
Transport of vitamins, nucleosides, and related molecules	33	1.21e-01	2.46e-01	0.203000	0.169000	1.13e-01	9.36e-02	2.61e-01
Glucuronidation	10	1.21e-01	2.47e-01	0.377000	-0.054000	3.73e-01	7.68e-01	4.11e-02
ALK mutants bind TKIs	10	1.22e-01	2.47e-01	0.379000	-0.359000	1.22e-01	4.92e-02	5.05e-01
Diseases associated with N-glycosylation of proteins	17	1.23e-01	2.50e-01	0.290000	-0.280000	7.53e-02	4.60e-02	5.91e-01
Keratinization	29	1.23e-01	2.50e-01	0.224000	-0.188000	1.21e-01	8.01e-02	2.58e-01
GPCR downstream signalling	257	1.24e-01	2.52e-01	0.074900	-0.072100	2.04e-02	4.72e-02	5.75e-01
RNA Polymerase II Pre-transcription Events	78	1.25e-01	2.52e-01	0.132000	-0.124000	-4.48e-02	5.82e-02	4.94e-01
DAP12 interactions	24	1.26e-01	2.54e-01	0.235000	-0.195000	-1.32e-01	9.89e-02	2.62e-01
RNA Polymerase III Abortive And Retractive Initiation	41	1.26e-01	2.54e-01	0.184000	-0.184000	4.04e-03	4.20e-02	9.64e-01
RNA Polymerase III Transcription	41	1.26e-01	2.54e-01	0.184000	-0.184000	4.04e-03	4.20e-02	9.64e-01
FCERI mediated Ca+2 mobilization	20	1.27e-01	2.54e-01	0.262000	-0.262000	-3.06e-03	4.23e-02	9.81e-01
Downregulation of SMAD2/3:SMAD4 transcriptional activity	27	1.27e-01	2.55e-01	0.228000	-0.220000	5.94e-02	4.77e-02	5.94e-01
PINK1-PRKN Mediated Mitophagy	20	1.28e-01	2.55e-01	0.264000	-0.259000	5.32e-02	4.53e-02	6.81e-01
Ca-dependent events	25	1.28e-01	2.55e-01	0.236000	0.042400	-2.32e-01	7.14e-01	4.46e-02
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon	14	1.28e-01	2.56e-01	0.307000	-0.238000	-1.93e-01	1.23e-01	2.11e-01
Disassembly of the destruction complex and recruitment of AXIN to the membrane	25	1.28e-01	2.56e-01	0.238000	-0.218000	9.48e-02	5.95e-02	4.12e-01
Beta-catenin phosphorylation cascade	17	1.28e-01	2.56e-01	0.289000	-0.241000	1.59e-01	8.52e-02	2.56e-01
Glutathione synthesis and recycling	12	1.30e-01	2.58e-01	0.332000	0.307000	1.28e-01	6.59e-02	4.44e-01
Transcriptional activation of mitochondrial biogenesis	50	1.30e-01	2.58e-01	0.168000	-0.094100	1.40e-01	2.50e-01	8.80e-02
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand	31	1.30e-01	2.58e-01	0.207000	-0.199000	-5.79e-02	5.52e-02	5.77e-01
Defective B4GALT7 causes EDS, progeroid type	14	1.30e-01	2.58e-01	0.311000	0.310000	2.13e-02	4.47e-02	8.90e-01
Retinoid metabolism and transport	35	1.32e-01	2.61e-01	0.193000	0.149000	1.23e-01	1.28e-01	2.09e-01
Peptide ligand-binding receptors	51	1.33e-01	2.63e-01	0.161000	0.038500	1.56e-01	6.35e-01	5.36e-02
Signaling by FGFR3 fusions in cancer	10	1.33e-01	2.63e-01	0.360000	-0.290000	-2.12e-01	1.12e-01	2.46e-01
PI3K Cascade	28	1.34e-01	2.64e-01	0.217000	-0.214000	-3.66e-02	4.98e-02	7.38e-01
Gamma carboxylation, hypusine formation and arylsulfatase activation	37	1.34e-01	2.64e-01	0.189000	0.046100	1.83e-01	6.27e-01	5.43e-02
Metabolism of amino acids and derivatives	315	1.34e-01	2.64e-01	0.066400	-0.064800	1.47e-02	4.88e-02	6.55e-01
Arachidonic acid metabolism	30	1.35e-01	2.65e-01	0.207000	0.160000	1.32e-01	1.31e-01	2.11e-01
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	30	1.36e-01	2.65e-01	0.207000	-0.118000	-1.70e-01	2.63e-01	1.08e-01
S33 mutants of beta-catenin aren’t phosphorylated	15	1.36e-01	2.65e-01	0.302000	-0.274000	1.28e-01	6.65e-02	3.91e-01
S37 mutants of beta-catenin aren’t phosphorylated	15	1.36e-01	2.65e-01	0.302000	-0.274000	1.28e-01	6.65e-02	3.91e-01
S45 mutants of beta-catenin aren’t phosphorylated	15	1.36e-01	2.65e-01	0.302000	-0.274000	1.28e-01	6.65e-02	3.91e-01
Signaling by CTNNB1 phospho-site mutants	15	1.36e-01	2.65e-01	0.302000	-0.274000	1.28e-01	6.65e-02	3.91e-01
Signaling by GSK3beta mutants	15	1.36e-01	2.65e-01	0.302000	-0.274000	1.28e-01	6.65e-02	3.91e-01
T41 mutants of beta-catenin aren’t phosphorylated	15	1.36e-01	2.65e-01	0.302000	-0.274000	1.28e-01	6.65e-02	3.91e-01
FRS-mediated FGFR4 signaling	12	1.36e-01	2.65e-01	0.326000	-0.250000	-2.09e-01	1.34e-01	2.09e-01
Mitochondrial biogenesis	71	1.37e-01	2.66e-01	0.140000	-0.108000	8.77e-02	1.14e-01	2.01e-01
PI-3K cascade:FGFR4	10	1.38e-01	2.68e-01	0.357000	-0.317000	-1.64e-01	8.22e-02	3.70e-01
Fatty acyl-CoA biosynthesis	29	1.39e-01	2.68e-01	0.210000	0.194000	8.17e-02	7.11e-02	4.47e-01
Interferon alpha/beta signaling	45	1.39e-01	2.68e-01	0.168000	0.097600	1.37e-01	2.57e-01	1.13e-01
Cell-Cell communication	90	1.40e-01	2.69e-01	0.123000	-0.102000	6.93e-02	9.47e-02	2.56e-01
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	23	1.40e-01	2.69e-01	0.236000	-0.229000	-6.00e-02	5.77e-02	6.18e-01
SHC-mediated cascade:FGFR4	10	1.40e-01	2.69e-01	0.360000	-0.357000	-4.68e-02	5.07e-02	7.98e-01
Oncogenic MAPK signaling	72	1.41e-01	2.70e-01	0.138000	-0.113000	7.84e-02	9.76e-02	2.51e-01
GRB2 events in EGFR signaling	10	1.41e-01	2.70e-01	0.363000	-0.360000	4.25e-02	4.86e-02	8.16e-01
RNA Polymerase III Transcription Termination	23	1.41e-01	2.70e-01	0.240000	-0.236000	4.21e-02	5.01e-02	7.27e-01
Regulation of localization of FOXO transcription factors	10	1.42e-01	2.71e-01	0.358000	-0.054200	-3.54e-01	7.66e-01	5.24e-02
Assembly Of The HIV Virion	16	1.42e-01	2.72e-01	0.286000	-0.285000	2.11e-02	4.84e-02	8.84e-01
FLT3 signaling in disease	26	1.43e-01	2.72e-01	0.224000	-0.223000	1.86e-02	4.88e-02	8.69e-01
RNA Polymerase III Transcription Initiation From Type 1 Promoter	28	1.44e-01	2.74e-01	0.214000	-0.212000	-2.69e-02	5.21e-02	8.05e-01
FRS-mediated FGFR1 signaling	12	1.45e-01	2.75e-01	0.321000	-0.241000	-2.12e-01	1.48e-01	2.03e-01
Elastic fibre formation	28	1.45e-01	2.76e-01	0.210000	0.160000	1.36e-01	1.43e-01	2.13e-01
MET promotes cell motility	27	1.46e-01	2.76e-01	0.214000	-0.148000	-1.55e-01	1.84e-01	1.64e-01
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	33	1.46e-01	2.76e-01	0.201000	-0.160000	1.22e-01	1.12e-01	2.26e-01
HS-GAG biosynthesis	22	1.46e-01	2.77e-01	0.237000	0.206000	1.17e-01	9.43e-02	3.41e-01
Hedgehog ‘off’ state	86	1.47e-01	2.77e-01	0.121000	-0.117000	-3.03e-02	6.06e-02	6.28e-01
Lysine catabolism	12	1.48e-01	2.78e-01	0.324000	0.319000	5.38e-02	5.56e-02	7.47e-01
Sensory perception of taste	13	1.49e-01	2.80e-01	0.307000	0.186000	2.43e-01	2.45e-01	1.29e-01
PI-3K cascade:FGFR1	10	1.50e-01	2.82e-01	0.350000	-0.307000	-1.67e-01	9.28e-02	3.60e-01
Activation of HOX genes during differentiation	52	1.51e-01	2.83e-01	0.157000	-0.155000	2.25e-02	5.31e-02	7.79e-01
Activation of anterior HOX genes in hindbrain development during early embryogenesis	52	1.51e-01	2.83e-01	0.157000	-0.155000	2.25e-02	5.31e-02	7.79e-01
Zinc transporters	15	1.51e-01	2.83e-01	0.294000	-0.115000	2.70e-01	4.39e-01	6.98e-02
Signaling by BRAF and RAF1 fusions	55	1.54e-01	2.87e-01	0.153000	-0.072300	1.35e-01	3.54e-01	8.27e-02
SHC-mediated cascade:FGFR1	10	1.56e-01	2.90e-01	0.350000	-0.346000	-5.01e-02	5.78e-02	7.84e-01
Erythropoietin activates RAS	13	1.56e-01	2.92e-01	0.308000	-0.307000	-1.91e-02	5.53e-02	9.05e-01
Glucagon signaling in metabolic regulation	19	1.57e-01	2.92e-01	0.260000	0.168000	-1.98e-01	2.05e-01	1.35e-01
IRS-related events triggered by IGF1R	34	1.57e-01	2.92e-01	0.189000	-0.186000	-3.47e-02	6.07e-02	7.27e-01
Aquaporin-mediated transport	28	1.58e-01	2.94e-01	0.213000	0.115000	-1.80e-01	2.94e-01	9.93e-02
CTLA4 inhibitory signaling	17	1.60e-01	2.96e-01	0.266000	-0.262000	-4.64e-02	6.14e-02	7.40e-01
Heparan sulfate/heparin (HS-GAG) metabolism	36	1.60e-01	2.96e-01	0.181000	0.143000	1.11e-01	1.38e-01	2.49e-01
Gastrin-CREB signalling pathway via PKC and MAPK	16	1.60e-01	2.96e-01	0.273000	-0.264000	-7.27e-02	6.80e-02	6.15e-01
G1/S Transition	127	1.61e-01	2.97e-01	0.097700	0.015400	9.65e-02	7.65e-01	6.08e-02
HS-GAG degradation	18	1.61e-01	2.97e-01	0.262000	0.255000	-6.07e-02	6.10e-02	6.56e-01
Regulation of FOXO transcriptional activity by acetylation	10	1.63e-01	3.01e-01	0.351000	-0.082400	3.41e-01	6.52e-01	6.21e-02
Chylomicron assembly	10	1.64e-01	3.01e-01	0.346000	0.029200	3.45e-01	8.73e-01	5.90e-02
FOXO-mediated transcription of cell cycle genes	14	1.64e-01	3.01e-01	0.295000	-0.291000	5.04e-02	5.95e-02	7.44e-01
Signaling by Hippo	18	1.66e-01	3.04e-01	0.253000	-0.139000	-2.12e-01	3.08e-01	1.20e-01
ATF4 activates genes in response to endoplasmic reticulum stress	26	1.66e-01	3.04e-01	0.219000	-0.182000	1.21e-01	1.09e-01	2.84e-01
SHC-mediated cascade:FGFR3	10	1.66e-01	3.04e-01	0.339000	-0.278000	-1.95e-01	1.28e-01	2.85e-01
Signaling by cytosolic FGFR1 fusion mutants	17	1.68e-01	3.07e-01	0.269000	-0.150000	2.24e-01	2.85e-01	1.10e-01
Neurotransmitter release cycle	31	1.69e-01	3.07e-01	0.199000	-0.108000	1.67e-01	2.97e-01	1.07e-01
WNT5A-dependent internalization of FZD4	12	1.69e-01	3.07e-01	0.318000	-0.301000	1.02e-01	7.08e-02	5.39e-01
Deadenylation of mRNA	24	1.70e-01	3.09e-01	0.225000	-0.212000	7.52e-02	7.24e-02	5.24e-01
InlB-mediated entry of Listeria monocytogenes into host cell	13	1.70e-01	3.09e-01	0.303000	-0.301000	2.97e-02	6.02e-02	8.53e-01
PKMTs methylate histone lysines	41	1.70e-01	3.09e-01	0.170000	-0.170000	1.50e-02	6.02e-02	8.68e-01
N-glycan antennae elongation in the medial/trans-Golgi	19	1.70e-01	3.09e-01	0.253000	-0.224000	1.19e-01	9.13e-02	3.70e-01
Orc1 removal from chromatin	67	1.72e-01	3.12e-01	0.135000	-0.085900	1.04e-01	2.24e-01	1.40e-01
Pyrimidine salvage	10	1.74e-01	3.14e-01	0.335000	0.264000	2.07e-01	1.49e-01	2.57e-01
SUMOylation of DNA replication proteins	45	1.74e-01	3.14e-01	0.158000	0.118000	1.05e-01	1.71e-01	2.23e-01
Pexophagy	11	1.76e-01	3.17e-01	0.327000	-0.321000	6.31e-02	6.55e-02	7.17e-01
Voltage gated Potassium channels	12	1.76e-01	3.17e-01	0.311000	0.009910	-3.11e-01	9.53e-01	6.23e-02
Recycling pathway of L1	24	1.77e-01	3.17e-01	0.222000	-0.215000	5.47e-02	6.86e-02	6.43e-01
Constitutive Signaling by Overexpressed ERBB2	11	1.77e-01	3.18e-01	0.325000	-0.323000	3.14e-02	6.33e-02	8.57e-01
Regulation of IFNA signaling	12	1.77e-01	3.18e-01	0.305000	0.258000	1.61e-01	1.21e-01	3.34e-01
Interleukin-37 signaling	15	1.78e-01	3.20e-01	0.280000	-0.083700	2.67e-01	5.75e-01	7.33e-02
Receptor Mediated Mitophagy	10	1.80e-01	3.22e-01	0.345000	-0.242000	2.46e-01	1.86e-01	1.78e-01
Transcriptional Regulation by VENTX	35	1.81e-01	3.23e-01	0.184000	0.127000	-1.33e-01	1.92e-01	1.73e-01
Mitochondrial translation initiation	87	1.81e-01	3.23e-01	0.113000	-0.046100	-1.03e-01	4.58e-01	9.65e-02
Striated Muscle Contraction	18	1.82e-01	3.24e-01	0.252000	0.251000	-2.50e-02	6.54e-02	8.54e-01
Paradoxical activation of RAF signaling by kinase inactive BRAF	38	1.83e-01	3.24e-01	0.176000	-0.134000	1.15e-01	1.54e-01	2.21e-01
Signaling by RAS mutants	38	1.83e-01	3.24e-01	0.176000	-0.134000	1.15e-01	1.54e-01	2.21e-01
Signaling by moderate kinase activity BRAF mutants	38	1.83e-01	3.24e-01	0.176000	-0.134000	1.15e-01	1.54e-01	2.21e-01
Signaling downstream of RAS mutants	38	1.83e-01	3.24e-01	0.176000	-0.134000	1.15e-01	1.54e-01	2.21e-01
NOTCH3 Activation and Transmission of Signal to the Nucleus	21	1.83e-01	3.24e-01	0.232000	-0.231000	-1.39e-02	6.67e-02	9.12e-01
Diseases of metabolism	179	1.85e-01	3.26e-01	0.078700	0.028600	7.33e-02	5.10e-01	9.14e-02
Signaling by ERBB2 ECD mutants	15	1.85e-01	3.26e-01	0.272000	-0.271000	-3.11e-02	6.95e-02	8.35e-01
TP53 Regulates Transcription of Death Receptors and Ligands	11	1.85e-01	3.26e-01	0.325000	-0.146000	2.90e-01	4.02e-01	9.59e-02
Regulation of gene expression in beta cells	13	1.86e-01	3.26e-01	0.300000	0.201000	-2.23e-01	2.11e-01	1.64e-01
Protein-protein interactions at synapses	52	1.86e-01	3.26e-01	0.145000	0.134000	5.49e-02	9.40e-02	4.94e-01
Signaling by FGFR4 in disease	11	1.89e-01	3.32e-01	0.312000	-0.254000	-1.81e-01	1.45e-01	3.00e-01
Mitochondrial translation elongation	87	1.90e-01	3.33e-01	0.111000	-0.063700	-9.10e-02	3.05e-01	1.43e-01
Collagen formation	53	1.91e-01	3.34e-01	0.142000	0.077700	1.19e-01	3.28e-01	1.35e-01
Disorders of Developmental Biology	12	1.92e-01	3.34e-01	0.298000	-0.265000	-1.36e-01	1.12e-01	4.15e-01
Disorders of Nervous System Development	12	1.92e-01	3.34e-01	0.298000	-0.265000	-1.36e-01	1.12e-01	4.15e-01
Loss of function of MECP2 in Rett syndrome	12	1.92e-01	3.34e-01	0.298000	-0.265000	-1.36e-01	1.12e-01	4.15e-01
Pervasive developmental disorders	12	1.92e-01	3.34e-01	0.298000	-0.265000	-1.36e-01	1.12e-01	4.15e-01
Chaperone Mediated Autophagy	17	1.92e-01	3.34e-01	0.259000	-0.225000	1.28e-01	1.08e-01	3.62e-01
Dual Incision in GG-NER	41	1.92e-01	3.34e-01	0.161000	0.130000	9.47e-02	1.50e-01	2.95e-01
Class A/1 (Rhodopsin-like receptors)	84	1.95e-01	3.39e-01	0.112000	0.086700	7.08e-02	1.70e-01	2.62e-01
IKK complex recruitment mediated by RIP1	20	1.96e-01	3.39e-01	0.229000	-0.198000	-1.15e-01	1.25e-01	3.72e-01
Autodegradation of Cdh1 by Cdh1:APC/C	63	1.99e-01	3.44e-01	0.131000	-0.130000	-8.91e-03	7.39e-02	9.03e-01
Glycogen breakdown (glycogenolysis)	15	2.00e-01	3.46e-01	0.270000	0.066100	-2.62e-01	6.58e-01	7.93e-02
CDK-mediated phosphorylation and removal of Cdc6	69	2.00e-01	3.46e-01	0.126000	-0.124000	1.95e-02	7.48e-02	7.80e-01
RNA Polymerase III Transcription Initiation From Type 2 Promoter	27	2.02e-01	3.47e-01	0.197000	-0.189000	-5.41e-02	8.88e-02	6.27e-01
Frs2-mediated activation	10	2.02e-01	3.47e-01	0.332000	-0.304000	1.33e-01	9.64e-02	4.67e-01
Signal transduction by L1	18	2.02e-01	3.48e-01	0.243000	-0.243000	-3.83e-03	7.41e-02	9.78e-01
Signaling by PDGFRA extracellular domain mutants	11	2.03e-01	3.48e-01	0.307000	-0.290000	-1.01e-01	9.60e-02	5.61e-01
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants	11	2.03e-01	3.48e-01	0.307000	-0.290000	-1.01e-01	9.60e-02	5.61e-01
Depolymerisation of the Nuclear Lamina	14	2.03e-01	3.49e-01	0.277000	-0.040600	2.74e-01	7.93e-01	7.60e-02
Antiviral mechanism by IFN-stimulated genes	77	2.05e-01	3.51e-01	0.120000	-0.076900	9.18e-02	2.44e-01	1.64e-01
Termination of O-glycan biosynthesis	10	2.05e-01	3.51e-01	0.330000	-0.157000	2.90e-01	3.90e-01	1.12e-01
The citric acid (TCA) cycle and respiratory electron transport	151	2.06e-01	3.51e-01	0.084400	0.013200	-8.34e-02	7.81e-01	7.74e-02
Assembly and cell surface presentation of NMDA receptors	17	2.06e-01	3.51e-01	0.253000	0.122000	-2.22e-01	3.82e-01	1.14e-01
Assembly of collagen fibrils and other multimeric structures	34	2.06e-01	3.51e-01	0.175000	0.173000	2.74e-02	8.13e-02	7.82e-01
RNA Polymerase II Transcription Termination	65	2.06e-01	3.51e-01	0.125000	-0.112000	-5.59e-02	1.18e-01	4.36e-01
Interleukin-10 signaling	18	2.07e-01	3.52e-01	0.237000	0.135000	1.95e-01	3.22e-01	1.52e-01
CD209 (DC-SIGN) signaling	18	2.12e-01	3.60e-01	0.239000	-0.239000	-1.37e-02	7.96e-02	9.20e-01
p75NTR recruits signalling complexes	12	2.12e-01	3.60e-01	0.291000	-0.285000	-5.85e-02	8.71e-02	7.26e-01
Signaling by ERBB2 in Cancer	19	2.16e-01	3.65e-01	0.233000	-0.232000	2.04e-02	8.02e-02	8.78e-01
SUMOylation of transcription cofactors	43	2.17e-01	3.67e-01	0.155000	-0.153000	2.40e-02	8.25e-02	7.85e-01
WNT ligand biogenesis and trafficking	11	2.18e-01	3.67e-01	0.301000	-0.292000	-7.30e-02	9.34e-02	6.75e-01
Cytochrome P450 - arranged by substrate type	44	2.18e-01	3.67e-01	0.152000	0.152000	6.18e-04	8.11e-02	9.94e-01
Glucose metabolism	81	2.18e-01	3.68e-01	0.112000	0.004980	1.12e-01	9.38e-01	8.22e-02
Fertilization	10	2.20e-01	3.71e-01	0.314000	-0.077700	-3.05e-01	6.71e-01	9.53e-02
Signaling by GPCR	289	2.22e-01	3.73e-01	0.060300	-0.056200	2.18e-02	1.01e-01	5.25e-01
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	45	2.22e-01	3.73e-01	0.150000	-0.149000	1.25e-02	8.32e-02	8.85e-01
Generation of second messenger molecules	14	2.25e-01	3.78e-01	0.268000	-0.263000	5.25e-02	8.83e-02	7.34e-01
NR1H2 and NR1H3-mediated signaling	40	2.27e-01	3.80e-01	0.160000	-0.099900	1.26e-01	2.74e-01	1.70e-01
Repression of WNT target genes	12	2.27e-01	3.80e-01	0.290000	-0.281000	7.06e-02	9.21e-02	6.72e-01
Translesion synthesis by POLI	17	2.28e-01	3.81e-01	0.237000	0.097400	2.16e-01	4.87e-01	1.23e-01
CDC6 association with the ORC:origin complex	11	2.29e-01	3.82e-01	0.297000	0.293000	4.60e-02	9.19e-02	7.92e-01
Mitochondrial translation termination	87	2.31e-01	3.85e-01	0.104000	-0.070500	-7.67e-02	2.56e-01	2.17e-01
Peptide hormone metabolism	50	2.32e-01	3.86e-01	0.140000	-0.140000	3.35e-03	8.72e-02	9.67e-01
Nucleotide salvage	20	2.32e-01	3.86e-01	0.217000	0.179000	1.22e-01	1.66e-01	3.44e-01
mRNA 3’-end processing	56	2.33e-01	3.87e-01	0.130000	-0.121000	-4.66e-02	1.16e-01	5.47e-01
Formation of Incision Complex in GG-NER	43	2.33e-01	3.87e-01	0.151000	0.150000	-2.03e-02	8.95e-02	8.18e-01
Endosomal Sorting Complex Required For Transport (ESCRT)	31	2.35e-01	3.89e-01	0.174000	-0.084400	-1.52e-01	4.16e-01	1.44e-01
Pentose phosphate pathway	13	2.36e-01	3.90e-01	0.276000	0.098900	-2.58e-01	5.37e-01	1.08e-01
Neurexins and neuroligins	36	2.37e-01	3.91e-01	0.161000	0.148000	6.35e-02	1.24e-01	5.10e-01
Diseases associated with O-glycosylation of proteins	36	2.37e-01	3.92e-01	0.161000	0.055200	1.51e-01	5.66e-01	1.16e-01
Interleukin-4 and Interleukin-13 signaling	66	2.38e-01	3.93e-01	0.123000	-0.063400	1.05e-01	3.74e-01	1.40e-01
Synthesis of PC	24	2.40e-01	3.96e-01	0.202000	-0.070900	1.89e-01	5.48e-01	1.10e-01
Synthesis of Leukotrienes (LT) and Eoxins (EX)	10	2.42e-01	3.97e-01	0.311000	-0.073700	3.02e-01	6.87e-01	9.86e-02
Chondroitin sulfate biosynthesis	14	2.43e-01	3.99e-01	0.265000	-0.180000	1.95e-01	2.45e-01	2.08e-01
Negative regulation of NMDA receptor-mediated neuronal transmission	15	2.44e-01	4.00e-01	0.254000	0.109000	-2.30e-01	4.64e-01	1.24e-01
Defects in cobalamin (B12) metabolism	12	2.44e-01	4.00e-01	0.278000	0.273000	5.00e-02	1.01e-01	7.64e-01
Positive epigenetic regulation of rRNA expression	44	2.45e-01	4.02e-01	0.145000	-0.145000	-1.43e-02	9.68e-02	8.70e-01
APC/C:Cdc20 mediated degradation of Securin	65	2.49e-01	4.06e-01	0.121000	-0.115000	3.70e-02	1.08e-01	6.06e-01
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	21	2.49e-01	4.07e-01	0.210000	0.010500	2.09e-01	9.34e-01	9.68e-02
RHO GTPases Activate ROCKs	19	2.50e-01	4.07e-01	0.225000	-0.174000	1.43e-01	1.89e-01	2.82e-01
Formation of the beta-catenin:TCF transactivating complex	30	2.50e-01	4.07e-01	0.179000	-0.158000	8.37e-02	1.35e-01	4.28e-01
Platelet calcium homeostasis	15	2.50e-01	4.07e-01	0.253000	-0.210000	1.41e-01	1.59e-01	3.45e-01
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	16	2.53e-01	4.11e-01	0.236000	0.221000	8.44e-02	1.27e-01	5.59e-01
Insulin processing	22	2.53e-01	4.11e-01	0.203000	-0.199000	-3.97e-02	1.07e-01	7.47e-01
Cell junction organization	64	2.56e-01	4.15e-01	0.122000	-0.090600	8.14e-02	2.10e-01	2.60e-01
Signaling by Erythropoietin	22	2.57e-01	4.16e-01	0.203000	-0.203000	1.14e-02	9.92e-02	9.26e-01
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	11	2.58e-01	4.17e-01	0.284000	-0.273000	-7.77e-02	1.17e-01	6.55e-01
Nuclear Pore Complex (NPC) Disassembly	35	2.58e-01	4.17e-01	0.158000	0.107000	1.16e-01	2.75e-01	2.35e-01
Other semaphorin interactions	10	2.59e-01	4.18e-01	0.306000	-0.190000	2.40e-01	2.98e-01	1.89e-01
Golgi Cisternae Pericentriolar Stack Reorganization	14	2.60e-01	4.19e-01	0.254000	-0.029900	2.53e-01	8.46e-01	1.02e-01
Visual phototransduction	68	2.61e-01	4.20e-01	0.117000	0.090800	-7.43e-02	1.96e-01	2.90e-01
Nef mediated downregulation of MHC class I complex cell surface expression	10	2.62e-01	4.21e-01	0.302000	0.085100	-2.90e-01	6.41e-01	1.13e-01
Regulation of TNFR1 signaling	34	2.62e-01	4.21e-01	0.160000	-0.147000	-6.37e-02	1.39e-01	5.21e-01
Translation of Replicase and Assembly of the Replication Transcription Complex	13	2.63e-01	4.22e-01	0.262000	-0.262000	1.29e-02	1.02e-01	9.36e-01
Regulated proteolysis of p75NTR	11	2.65e-01	4.24e-01	0.278000	-0.202000	-1.91e-01	2.46e-01	2.73e-01
DAG and IP3 signaling	30	2.65e-01	4.24e-01	0.173000	0.027000	-1.71e-01	7.98e-01	1.06e-01
A tetrasaccharide linker sequence is required for GAG synthesis	18	2.65e-01	4.24e-01	0.219000	0.212000	5.75e-02	1.20e-01	6.73e-01
Signaling by FLT3 ITD and TKD mutants	14	2.66e-01	4.24e-01	0.253000	-0.249000	4.44e-02	1.07e-01	7.74e-01
Phenylalanine and tyrosine metabolism	10	2.66e-01	4.24e-01	0.292000	0.239000	1.67e-01	1.90e-01	3.61e-01
RHO GTPases activate PAKs	20	2.66e-01	4.24e-01	0.208000	-0.199000	-6.01e-02	1.24e-01	6.42e-01
Biotin transport and metabolism	11	2.67e-01	4.24e-01	0.287000	-0.269000	9.77e-02	1.22e-01	5.75e-01
Nuclear Envelope (NE) Reassembly	69	2.67e-01	4.25e-01	0.112000	0.018000	1.11e-01	7.96e-01	1.11e-01
Interleukin-3, Interleukin-5 and GM-CSF signaling	29	2.68e-01	4.26e-01	0.172000	-0.167000	-4.20e-02	1.19e-01	6.96e-01
APC/C:Cdc20 mediated degradation of Cyclin B	24	2.69e-01	4.27e-01	0.193000	0.188000	-4.41e-02	1.12e-01	7.09e-01
Metabolic disorders of biological oxidation enzymes	27	2.69e-01	4.27e-01	0.182000	0.176000	-4.73e-02	1.14e-01	6.71e-01
FGFR1 mutant receptor activation	23	2.70e-01	4.27e-01	0.198000	-0.105000	1.68e-01	3.83e-01	1.62e-01
Early Phase of HIV Life Cycle	12	2.70e-01	4.28e-01	0.265000	0.132000	2.30e-01	4.29e-01	1.68e-01
Myogenesis	19	2.72e-01	4.29e-01	0.212000	-0.206000	-5.07e-02	1.21e-01	7.02e-01
Sema4D in semaphorin signaling	24	2.74e-01	4.32e-01	0.194000	-0.143000	1.30e-01	2.25e-01	2.69e-01
Rap1 signalling	11	2.74e-01	4.32e-01	0.276000	-0.093600	-2.60e-01	5.91e-01	1.35e-01
Late Phase of HIV Life Cycle	132	2.75e-01	4.32e-01	0.080400	-0.078300	-1.81e-02	1.21e-01	7.21e-01
MicroRNA (miRNA) biogenesis	24	2.75e-01	4.33e-01	0.193000	-0.137000	1.36e-01	2.45e-01	2.49e-01
ABC transporters in lipid homeostasis	14	2.76e-01	4.33e-01	0.248000	0.248000	-2.10e-02	1.09e-01	8.92e-01
G alpha (q) signalling events	93	2.77e-01	4.33e-01	0.095300	-0.092500	-2.27e-02	1.23e-01	7.05e-01
Metabolism of fat-soluble vitamins	39	2.77e-01	4.33e-01	0.146000	0.076400	1.24e-01	4.09e-01	1.80e-01
activated TAK1 mediates p38 MAPK activation	18	2.78e-01	4.33e-01	0.222000	-0.190000	1.14e-01	1.62e-01	4.04e-01
Diseases associated with the TLR signaling cascade	22	2.78e-01	4.33e-01	0.194000	0.163000	1.04e-01	1.85e-01	3.99e-01
Diseases of Immune System	22	2.78e-01	4.33e-01	0.194000	0.163000	1.04e-01	1.85e-01	3.99e-01
Interleukin-6 family signaling	19	2.78e-01	4.33e-01	0.215000	-0.079300	2.00e-01	5.50e-01	1.32e-01
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	12	2.80e-01	4.36e-01	0.270000	0.112000	-2.46e-01	5.03e-01	1.40e-01
MECP2 regulates neuronal receptors and channels	13	2.82e-01	4.38e-01	0.252000	-0.237000	-8.50e-02	1.39e-01	5.96e-01
Cardiac conduction	66	2.83e-01	4.39e-01	0.114000	-0.112000	2.00e-02	1.15e-01	7.79e-01
SUMOylation of immune response proteins	11	2.83e-01	4.39e-01	0.273000	-0.259000	-8.63e-02	1.37e-01	6.20e-01
Establishment of Sister Chromatid Cohesion	11	2.83e-01	4.39e-01	0.281000	0.120000	-2.54e-01	4.92e-01	1.45e-01
YAP1- and WWTR1 (TAZ)-stimulated gene expression	12	2.86e-01	4.43e-01	0.268000	-0.117000	2.41e-01	4.82e-01	1.49e-01
Protein localization	150	2.87e-01	4.44e-01	0.075200	-0.010300	7.45e-02	8.28e-01	1.16e-01
Role of phospholipids in phagocytosis	17	2.88e-01	4.44e-01	0.225000	-0.140000	1.77e-01	3.17e-01	2.07e-01
Netrin-1 signaling	35	2.88e-01	4.44e-01	0.153000	-0.146000	-4.31e-02	1.34e-01	6.59e-01
Synthesis of bile acids and bile salts via 24-hydroxycholesterol	14	2.91e-01	4.49e-01	0.238000	-0.176000	-1.60e-01	2.55e-01	3.00e-01
Downstream signal transduction	28	2.94e-01	4.52e-01	0.172000	-0.169000	3.25e-02	1.22e-01	7.66e-01
Mitochondrial iron-sulfur cluster biogenesis	13	2.94e-01	4.52e-01	0.254000	0.229000	-1.11e-01	1.53e-01	4.90e-01
The NLRP3 inflammasome	14	2.95e-01	4.53e-01	0.239000	0.056600	2.32e-01	7.14e-01	1.33e-01
Recognition of DNA damage by PCNA-containing replication complex	30	2.96e-01	4.54e-01	0.163000	0.043100	1.57e-01	6.83e-01	1.37e-01
Diseases associated with glycosaminoglycan metabolism	29	2.96e-01	4.54e-01	0.166000	0.164000	2.50e-02	1.25e-01	8.16e-01
B-WICH complex positively regulates rRNA expression	29	2.97e-01	4.55e-01	0.169000	-0.164000	3.86e-02	1.26e-01	7.19e-01
Gene Silencing by RNA	68	2.98e-01	4.56e-01	0.110000	-0.023700	1.07e-01	7.36e-01	1.26e-01
N-Glycan antennae elongation	12	2.99e-01	4.57e-01	0.263000	-0.239000	1.11e-01	1.52e-01	5.07e-01
Amyloid fiber formation	41	3.00e-01	4.58e-01	0.139000	0.035900	1.34e-01	6.91e-01	1.38e-01
Defective B3GAT3 causes JDSSDHD	14	3.02e-01	4.60e-01	0.238000	0.238000	1.11e-02	1.23e-01	9.43e-01
Formation of HIV-1 elongation complex containing HIV-1 Tat	42	3.03e-01	4.60e-01	0.138000	-0.138000	8.41e-04	1.22e-01	9.92e-01
HIV Transcription Elongation	42	3.03e-01	4.60e-01	0.138000	-0.138000	8.41e-04	1.22e-01	9.92e-01
Tat-mediated elongation of the HIV-1 transcript	42	3.03e-01	4.60e-01	0.138000	-0.138000	8.41e-04	1.22e-01	9.92e-01
Ion transport by P-type ATPases	36	3.03e-01	4.60e-01	0.152000	-0.122000	8.97e-02	2.04e-01	3.52e-01
Opioid Signalling	60	3.04e-01	4.61e-01	0.113000	-0.093900	-6.29e-02	2.08e-01	4.00e-01
Transmission across Chemical Synapses	146	3.05e-01	4.62e-01	0.073700	-0.006410	-7.34e-02	8.94e-01	1.26e-01
Ephrin signaling	15	3.06e-01	4.63e-01	0.227000	-0.216000	-6.90e-02	1.48e-01	6.44e-01
Abortive elongation of HIV-1 transcript in the absence of Tat	23	3.12e-01	4.71e-01	0.186000	-0.180000	4.35e-02	1.34e-01	7.18e-01
Recycling of bile acids and salts	13	3.13e-01	4.73e-01	0.245000	-0.037300	2.43e-01	8.16e-01	1.30e-01
Glycosaminoglycan metabolism	90	3.14e-01	4.73e-01	0.093600	-0.017700	9.19e-02	7.71e-01	1.32e-01
RND3 GTPase cycle	36	3.14e-01	4.73e-01	0.149000	-0.057500	1.37e-01	5.51e-01	1.55e-01
Cristae formation	13	3.16e-01	4.75e-01	0.248000	-0.173000	1.77e-01	2.79e-01	2.68e-01
Transcriptional regulation of white adipocyte differentiation	74	3.19e-01	4.80e-01	0.103000	-0.092900	4.49e-02	1.67e-01	5.05e-01
Diseases associated with glycosylation precursor biosynthesis	18	3.20e-01	4.80e-01	0.206000	-0.019600	2.05e-01	8.86e-01	1.32e-01
Downstream signaling of activated FGFR2	17	3.21e-01	4.81e-01	0.207000	-0.151000	-1.41e-01	2.81e-01	3.13e-01
Budding and maturation of HIV virion	28	3.21e-01	4.81e-01	0.162000	-0.145000	-7.30e-02	1.86e-01	5.04e-01
Sensory Perception	134	3.22e-01	4.83e-01	0.076700	0.064600	-4.14e-02	1.97e-01	4.09e-01
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	17	3.23e-01	4.83e-01	0.214000	-0.198000	7.93e-02	1.57e-01	5.71e-01
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	13	3.24e-01	4.85e-01	0.245000	0.200000	-1.41e-01	2.11e-01	3.80e-01
Interleukin receptor SHC signaling	17	3.25e-01	4.85e-01	0.209000	-0.208000	-2.10e-02	1.38e-01	8.81e-01
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	10	3.25e-01	4.85e-01	0.271000	-0.266000	-5.32e-02	1.45e-01	7.71e-01
Interleukin-20 family signaling	15	3.26e-01	4.85e-01	0.219000	0.178000	1.27e-01	2.32e-01	3.93e-01
Signaling by ERBB2 KD Mutants	18	3.27e-01	4.86e-01	0.203000	-0.203000	-8.86e-03	1.36e-01	9.48e-01
Diseases of programmed cell death	41	3.33e-01	4.95e-01	0.132000	0.113000	6.77e-02	2.12e-01	4.54e-01
NCAM1 interactions	18	3.34e-01	4.95e-01	0.198000	0.139000	1.41e-01	3.08e-01	3.01e-01
Mitochondrial protein import	61	3.34e-01	4.95e-01	0.108000	-0.075300	-7.68e-02	3.10e-01	3.00e-01
Deactivation of the beta-catenin transactivating complex	38	3.34e-01	4.95e-01	0.136000	-0.113000	-7.69e-02	2.30e-01	4.13e-01
Defective B3GALT6 causes EDSP2 and SEMDJL1	14	3.35e-01	4.95e-01	0.226000	0.222000	4.62e-02	1.51e-01	7.65e-01
Respiratory electron transport	103	3.42e-01	5.05e-01	0.082500	-0.029300	-7.71e-02	6.08e-01	1.77e-01
Signaling by Non-Receptor Tyrosine Kinases	44	3.42e-01	5.05e-01	0.129000	-0.122000	4.33e-02	1.63e-01	6.19e-01
Signaling by PTK6	44	3.42e-01	5.05e-01	0.129000	-0.122000	4.33e-02	1.63e-01	6.19e-01
The role of Nef in HIV-1 replication and disease pathogenesis	23	3.46e-01	5.08e-01	0.172000	-0.136000	-1.06e-01	2.60e-01	3.80e-01
Membrane binding and targetting of GAG proteins	14	3.46e-01	5.08e-01	0.223000	-0.214000	-6.16e-02	1.66e-01	6.90e-01
Synthesis And Processing Of GAG, GAGPOL Polyproteins	14	3.46e-01	5.08e-01	0.223000	-0.214000	-6.16e-02	1.66e-01	6.90e-01
FGFR2 alternative splicing	25	3.46e-01	5.08e-01	0.172000	-0.129000	1.13e-01	2.63e-01	3.28e-01
Transport of Mature mRNAs Derived from Intronless Transcripts	42	3.46e-01	5.08e-01	0.131000	-0.023300	1.29e-01	7.94e-01	1.49e-01
Interleukin-15 signaling	12	3.47e-01	5.08e-01	0.242000	0.022000	2.41e-01	8.95e-01	1.49e-01
Mucopolysaccharidoses	11	3.48e-01	5.09e-01	0.258000	-0.149000	2.10e-01	3.91e-01	2.28e-01
VEGFR2 mediated vascular permeability	22	3.48e-01	5.09e-01	0.176000	-0.156000	-8.08e-02	2.05e-01	5.12e-01
Killing mechanisms	10	3.51e-01	5.11e-01	0.263000	-0.023900	-2.62e-01	8.96e-01	1.51e-01
WNT5:FZD7-mediated leishmania damping	10	3.51e-01	5.11e-01	0.263000	-0.023900	-2.62e-01	8.96e-01	1.51e-01
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	12	3.52e-01	5.13e-01	0.240000	0.013900	2.40e-01	9.34e-01	1.50e-01
Endogenous sterols	22	3.52e-01	5.13e-01	0.178000	0.178000	-8.06e-03	1.49e-01	9.48e-01
p130Cas linkage to MAPK signaling for integrins	13	3.53e-01	5.13e-01	0.230000	0.027500	2.28e-01	8.64e-01	1.54e-01
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	42	3.53e-01	5.13e-01	0.131000	0.105000	-7.86e-02	2.40e-01	3.78e-01
PLC beta mediated events	33	3.54e-01	5.13e-01	0.143000	-0.042900	-1.37e-01	6.70e-01	1.74e-01
IRAK1 recruits IKK complex	10	3.55e-01	5.14e-01	0.262000	-0.261000	-1.90e-02	1.53e-01	9.17e-01
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	10	3.55e-01	5.14e-01	0.262000	-0.261000	-1.90e-02	1.53e-01	9.17e-01
Mitotic Telophase/Cytokinesis	13	3.55e-01	5.14e-01	0.234000	0.116000	-2.04e-01	4.69e-01	2.04e-01
Epigenetic regulation of gene expression	85	3.55e-01	5.14e-01	0.090800	-0.089700	1.43e-02	1.53e-01	8.19e-01
p38MAPK events	13	3.56e-01	5.14e-01	0.231000	-0.230000	2.45e-02	1.52e-01	8.78e-01
Global Genome Nucleotide Excision Repair (GG-NER)	84	3.57e-01	5.15e-01	0.090500	0.090500	1.76e-03	1.52e-01	9.78e-01
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	25	3.58e-01	5.15e-01	0.167000	-0.164000	3.19e-02	1.57e-01	7.82e-01
RNA Polymerase III Transcription Initiation	36	3.59e-01	5.17e-01	0.138000	-0.138000	-1.36e-03	1.53e-01	9.89e-01
Formation of HIV elongation complex in the absence of HIV Tat	44	3.63e-01	5.21e-01	0.124000	-0.123000	-1.33e-02	1.59e-01	8.79e-01
Phase 0 - rapid depolarisation	17	3.66e-01	5.26e-01	0.201000	0.072600	-1.88e-01	6.04e-01	1.81e-01
NRIF signals cell death from the nucleus	15	3.67e-01	5.26e-01	0.207000	-0.159000	-1.33e-01	2.87e-01	3.73e-01
Translesion synthesis by REV1	16	3.68e-01	5.27e-01	0.202000	0.053300	1.95e-01	7.12e-01	1.77e-01
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	48	3.72e-01	5.33e-01	0.120000	-0.094400	7.34e-02	2.58e-01	3.79e-01
EPH-ephrin mediated repulsion of cells	38	3.74e-01	5.34e-01	0.132000	-0.131000	2.08e-02	1.64e-01	8.25e-01
Glycerophospholipid biosynthesis	90	3.74e-01	5.34e-01	0.085400	0.003240	8.54e-02	9.58e-01	1.62e-01
FRS-mediated FGFR2 signaling	12	3.74e-01	5.34e-01	0.230000	-0.092200	-2.11e-01	5.80e-01	2.06e-01
BBSome-mediated cargo-targeting to cilium	23	3.76e-01	5.36e-01	0.168000	0.017400	1.67e-01	8.85e-01	1.66e-01
GAB1 signalosome	14	3.78e-01	5.38e-01	0.215000	-0.214000	-1.77e-02	1.66e-01	9.09e-01
Activation of BH3-only proteins	28	3.78e-01	5.38e-01	0.150000	-0.137000	-6.14e-02	2.10e-01	5.74e-01
G-protein mediated events	37	3.79e-01	5.38e-01	0.130000	-0.064800	-1.13e-01	4.95e-01	2.35e-01
Cell surface interactions at the vascular wall	86	3.80e-01	5.38e-01	0.088500	-0.073000	5.01e-02	2.42e-01	4.23e-01
Glucagon-type ligand receptors	11	3.80e-01	5.38e-01	0.246000	0.226000	-9.64e-02	1.94e-01	5.80e-01
TRAF6 mediated IRF7 activation	15	3.80e-01	5.38e-01	0.204000	-0.171000	-1.10e-01	2.50e-01	4.61e-01
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	108	3.80e-01	5.38e-01	0.077000	-0.012000	-7.61e-02	8.29e-01	1.72e-01
TNF signaling	43	3.81e-01	5.39e-01	0.120000	-0.090300	-7.91e-02	3.06e-01	3.70e-01
Translesion synthesis by POLK	17	3.85e-01	5.44e-01	0.191000	0.075500	1.75e-01	5.90e-01	2.12e-01
Lewis blood group biosynthesis	11	3.86e-01	5.45e-01	0.242000	-0.042600	2.38e-01	8.07e-01	1.72e-01
Signaling by BMP	16	3.87e-01	5.45e-01	0.202000	0.087800	-1.82e-01	5.43e-01	2.08e-01
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS)	11	3.87e-01	5.45e-01	0.242000	0.234000	-6.36e-02	1.80e-01	7.15e-01
Diseases of hemostasis	11	3.87e-01	5.45e-01	0.242000	0.234000	-6.36e-02	1.80e-01	7.15e-01
MET activates PTK2 signaling	16	3.88e-01	5.45e-01	0.195000	-0.125000	-1.49e-01	3.85e-01	3.02e-01
Oxidative Stress Induced Senescence	63	3.92e-01	5.50e-01	0.102000	-0.053900	8.61e-02	4.59e-01	2.38e-01
VLDLR internalisation and degradation	12	3.95e-01	5.53e-01	0.232000	-0.181000	1.44e-01	2.77e-01	3.87e-01
Regulation of gene expression by Hypoxia-inducible Factor	11	3.95e-01	5.53e-01	0.240000	-0.228000	7.39e-02	1.90e-01	6.71e-01
Postmitotic nuclear pore complex (NPC) reformation	27	3.98e-01	5.56e-01	0.153000	-0.067000	1.38e-01	5.47e-01	2.15e-01
Nuclear events stimulated by ALK signaling in cancer	17	3.98e-01	5.56e-01	0.192000	-0.183000	6.05e-02	1.92e-01	6.66e-01
Regulation of TP53 Activity through Methylation	19	3.98e-01	5.56e-01	0.180000	-0.180000	6.77e-03	1.75e-01	9.59e-01
Nucleotide biosynthesis	14	4.01e-01	5.59e-01	0.211000	0.202000	-6.03e-02	1.91e-01	6.96e-01
Complex I biogenesis	57	4.01e-01	5.59e-01	0.104000	0.021800	-1.02e-01	7.76e-01	1.83e-01
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases	14	4.03e-01	5.62e-01	0.208000	-0.208000	9.45e-04	1.78e-01	9.95e-01
Tight junction interactions	21	4.04e-01	5.62e-01	0.169000	0.025800	1.67e-01	8.38e-01	1.87e-01
RHO GTPases activate KTN1	11	4.06e-01	5.64e-01	0.235000	-0.232000	3.47e-02	1.82e-01	8.42e-01
Pyroptosis	20	4.07e-01	5.64e-01	0.177000	0.105000	-1.42e-01	4.18e-01	2.71e-01
Hyaluronan metabolism	13	4.08e-01	5.64e-01	0.218000	-0.199000	8.69e-02	2.13e-01	5.87e-01
Transport of the SLBP Dependant Mature mRNA	35	4.08e-01	5.64e-01	0.132000	-0.024900	1.29e-01	7.99e-01	1.86e-01
O-linked glycosylation	64	4.08e-01	5.64e-01	0.095900	0.022700	9.31e-02	7.53e-01	1.98e-01
Organic cation/anion/zwitterion transport	11	4.08e-01	5.64e-01	0.231000	-0.224000	-5.45e-02	1.98e-01	7.54e-01
Neuronal System	207	4.09e-01	5.64e-01	0.055000	0.027500	-4.76e-02	4.96e-01	2.39e-01
Leishmania infection	133	4.09e-01	5.64e-01	0.067400	-0.067300	4.16e-03	1.81e-01	9.34e-01
Blood group systems biosynthesis	13	4.10e-01	5.65e-01	0.212000	0.044600	2.07e-01	7.81e-01	1.96e-01
Synthesis of bile acids and bile salts via 27-hydroxycholesterol	14	4.11e-01	5.65e-01	0.205000	-0.205000	-1.21e-02	1.84e-01	9.38e-01
tRNA processing	114	4.13e-01	5.67e-01	0.073500	0.062100	-3.93e-02	2.53e-01	4.69e-01
Listeria monocytogenes entry into host cells	18	4.13e-01	5.67e-01	0.184000	-0.099900	1.55e-01	4.63e-01	2.55e-01
Molecules associated with elastic fibres	19	4.18e-01	5.74e-01	0.172000	0.114000	1.28e-01	3.88e-01	3.35e-01
Vpr-mediated nuclear import of PICs	33	4.20e-01	5.76e-01	0.132000	0.021100	1.30e-01	8.34e-01	1.97e-01
Signaling by FLT3 fusion proteins	18	4.21e-01	5.77e-01	0.178000	-0.175000	-2.97e-02	1.98e-01	8.27e-01
Transport of Mature Transcript to Cytoplasm	80	4.21e-01	5.77e-01	0.085600	-0.084500	1.33e-02	1.92e-01	8.37e-01
Signaling by WNT in cancer	32	4.23e-01	5.78e-01	0.134000	-0.133000	-1.01e-02	1.92e-01	9.22e-01
Signaling by RAF1 mutants	34	4.25e-01	5.81e-01	0.132000	-0.086700	9.97e-02	3.82e-01	3.14e-01
Regulation of RUNX1 Expression and Activity	17	4.26e-01	5.81e-01	0.187000	-0.117000	1.45e-01	4.04e-01	2.99e-01
ISG15 antiviral mechanism	72	4.26e-01	5.81e-01	0.090600	-0.045100	7.86e-02	5.09e-01	2.49e-01
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	13	4.28e-01	5.83e-01	0.207000	-0.205000	-2.80e-02	2.00e-01	8.61e-01
Interactions of Vpr with host cellular proteins	36	4.29e-01	5.83e-01	0.126000	-0.023900	1.24e-01	8.04e-01	1.98e-01
Syndecan interactions	17	4.29e-01	5.83e-01	0.186000	-0.149000	1.11e-01	2.88e-01	4.29e-01
Laminin interactions	21	4.29e-01	5.83e-01	0.166000	0.059600	-1.55e-01	6.36e-01	2.19e-01
RAS processing	17	4.31e-01	5.85e-01	0.185000	-0.135000	1.27e-01	3.37e-01	3.63e-01
Nonhomologous End-Joining (NHEJ)	34	4.31e-01	5.85e-01	0.126000	0.111000	6.07e-02	2.64e-01	5.41e-01
Sema3A PAK dependent Axon repulsion	14	4.32e-01	5.85e-01	0.196000	-0.134000	-1.43e-01	3.86e-01	3.53e-01
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	11	4.34e-01	5.87e-01	0.229000	-0.161000	1.63e-01	3.54e-01	3.49e-01
Ion homeostasis	35	4.35e-01	5.87e-01	0.129000	-0.101000	7.91e-02	3.00e-01	4.18e-01
Synthesis of IP3 and IP4 in the cytosol	20	4.35e-01	5.87e-01	0.169000	-0.159000	5.64e-02	2.18e-01	6.62e-01
Carnitine metabolism	11	4.35e-01	5.87e-01	0.223000	0.220000	3.42e-02	2.05e-01	8.44e-01
Signaling by NODAL	15	4.36e-01	5.87e-01	0.190000	0.066900	1.77e-01	6.54e-01	2.34e-01
Cell death signalling via NRAGE, NRIF and NADE	65	4.38e-01	5.90e-01	0.092100	-0.092100	1.89e-04	1.99e-01	9.98e-01
RAB geranylgeranylation	52	4.39e-01	5.90e-01	0.104000	-0.098900	3.23e-02	2.18e-01	6.87e-01
G alpha (s) signalling events	50	4.39e-01	5.90e-01	0.107000	-0.049700	9.43e-02	5.43e-01	2.49e-01
Interleukin-6 signaling	10	4.39e-01	5.90e-01	0.238000	-0.102000	2.15e-01	5.76e-01	2.40e-01
Interleukin-7 signaling	16	4.41e-01	5.91e-01	0.181000	0.134000	1.22e-01	3.54e-01	3.98e-01
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	69	4.41e-01	5.91e-01	0.090900	-0.064200	6.43e-02	3.57e-01	3.56e-01
Cobalamin (Cbl, vitamin B12) transport and metabolism	14	4.45e-01	5.96e-01	0.194000	0.187000	5.09e-02	2.25e-01	7.42e-01
Late endosomal microautophagy	29	4.46e-01	5.96e-01	0.137000	-0.136000	1.29e-02	2.04e-01	9.05e-01
Signaling by ERBB2 TMD/JMD mutants	15	4.47e-01	5.97e-01	0.190000	-0.189000	2.23e-02	2.06e-01	8.81e-01
Association of TriC/CCT with target proteins during biosynthesis	38	4.49e-01	5.99e-01	0.119000	-0.118000	1.39e-02	2.07e-01	8.82e-01
TP53 Regulates Transcription of DNA Repair Genes	61	4.49e-01	5.99e-01	0.095500	-0.076600	5.69e-02	3.01e-01	4.42e-01
Aggrephagy	20	4.50e-01	6.00e-01	0.166000	-0.151000	6.76e-02	2.42e-01	6.01e-01
TP53 Regulates Transcription of Caspase Activators and Caspases	11	4.52e-01	6.02e-01	0.219000	0.218000	1.39e-02	2.10e-01	9.37e-01
TRAF3-dependent IRF activation pathway	13	4.53e-01	6.02e-01	0.198000	-0.161000	-1.15e-01	3.15e-01	4.73e-01
Transport of Mature mRNA derived from an Intron-Containing Transcript	71	4.54e-01	6.02e-01	0.086100	-0.086100	-3.32e-03	2.10e-01	9.61e-01
Long-term potentiation	12	4.54e-01	6.02e-01	0.213000	0.117000	-1.78e-01	4.83e-01	2.85e-01
The canonical retinoid cycle in rods (twilight vision)	16	4.55e-01	6.03e-01	0.180000	0.179000	2.11e-02	2.15e-01	8.84e-01
Chondroitin sulfate/dermatan sulfate metabolism	40	4.55e-01	6.03e-01	0.115000	0.001610	1.15e-01	9.86e-01	2.10e-01
Transport of Mature mRNA Derived from an Intronless Transcript	41	4.57e-01	6.04e-01	0.113000	-0.002860	1.13e-01	9.75e-01	2.11e-01
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	17	4.58e-01	6.05e-01	0.176000	-0.174000	2.72e-02	2.14e-01	8.46e-01
Josephin domain DUBs	10	4.60e-01	6.07e-01	0.231000	-0.102000	2.07e-01	5.75e-01	2.56e-01
Synthesis of bile acids and bile salts	31	4.63e-01	6.10e-01	0.128000	-0.128000	-9.60e-03	2.17e-01	9.26e-01
Synthesis of IP2, IP, and Ins in the cytosol	12	4.64e-01	6.11e-01	0.203000	0.156000	1.30e-01	3.50e-01	4.37e-01
Keratan sulfate/keratin metabolism	25	4.64e-01	6.11e-01	0.145000	-0.132000	6.05e-02	2.53e-01	6.01e-01
Citric acid cycle (TCA cycle)	21	4.65e-01	6.12e-01	0.158000	0.055700	-1.48e-01	6.59e-01	2.41e-01
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	24	4.66e-01	6.13e-01	0.144000	-0.035800	-1.40e-01	7.62e-01	2.36e-01
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	70	4.67e-01	6.13e-01	0.087000	-0.053000	6.90e-02	4.44e-01	3.18e-01
Signaling by FGFR1 in disease	30	4.67e-01	6.13e-01	0.133000	-0.112000	7.11e-02	2.89e-01	5.01e-01
Potassium Channels	37	4.71e-01	6.17e-01	0.118000	0.046000	-1.09e-01	6.28e-01	2.51e-01
Pyruvate metabolism and Citric Acid (TCA) cycle	47	4.72e-01	6.18e-01	0.105000	0.072100	-7.69e-02	3.93e-01	3.62e-01
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer’s disease models	20	4.73e-01	6.18e-01	0.161000	-0.085200	1.36e-01	5.10e-01	2.91e-01
Neurodegenerative Diseases	20	4.73e-01	6.18e-01	0.161000	-0.085200	1.36e-01	5.10e-01	2.91e-01
SLC transporter disorders	70	4.74e-01	6.18e-01	0.085100	-0.016800	8.35e-02	8.08e-01	2.28e-01
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	35	4.74e-01	6.18e-01	0.122000	-0.095600	7.53e-02	3.28e-01	4.41e-01
Signal regulatory protein family interactions	10	4.76e-01	6.20e-01	0.220000	0.206000	7.62e-02	2.59e-01	6.76e-01
RHO GTPases activate CIT	19	4.78e-01	6.22e-01	0.161000	0.009130	1.60e-01	9.45e-01	2.26e-01
Glutamate binding, activation of AMPA receptors and synaptic plasticity	21	4.79e-01	6.22e-01	0.153000	0.005430	-1.53e-01	9.66e-01	2.25e-01
Trafficking of AMPA receptors	21	4.79e-01	6.22e-01	0.153000	0.005430	-1.53e-01	9.66e-01	2.25e-01
RA biosynthesis pathway	15	4.79e-01	6.22e-01	0.177000	0.142000	1.06e-01	3.41e-01	4.75e-01
Prostacyclin signalling through prostacyclin receptor	10	4.80e-01	6.23e-01	0.225000	0.201000	-9.95e-02	2.70e-01	5.86e-01
Aflatoxin activation and detoxification	15	4.81e-01	6.23e-01	0.182000	0.045400	-1.76e-01	7.61e-01	2.37e-01
Unblocking of NMDA receptors, glutamate binding and activation	11	4.82e-01	6.24e-01	0.213000	0.079500	-1.98e-01	6.48e-01	2.56e-01
Sema4D induced cell migration and growth-cone collapse	20	4.83e-01	6.24e-01	0.158000	-0.066000	1.44e-01	6.09e-01	2.66e-01
Transcriptional regulation by small RNAs	47	4.86e-01	6.28e-01	0.101000	0.005380	1.01e-01	9.49e-01	2.32e-01
Caspase-mediated cleavage of cytoskeletal proteins	11	4.87e-01	6.29e-01	0.207000	0.050800	2.00e-01	7.71e-01	2.50e-01
RNA Polymerase III Chain Elongation	18	4.89e-01	6.30e-01	0.164000	-0.159000	4.19e-02	2.43e-01	7.58e-01
MET activates RAP1 and RAC1	10	4.92e-01	6.33e-01	0.214000	-0.186000	-1.05e-01	3.08e-01	5.65e-01
Other interleukin signaling	18	4.92e-01	6.33e-01	0.162000	0.001290	1.62e-01	9.92e-01	2.34e-01
Inositol phosphate metabolism	37	4.93e-01	6.34e-01	0.115000	-0.103000	5.03e-02	2.78e-01	5.97e-01
CLEC7A (Dectin-1) induces NFAT activation	10	4.95e-01	6.36e-01	0.219000	-0.207000	7.24e-02	2.57e-01	6.92e-01
KSRP (KHSRP) binds and destabilizes mRNA	17	4.96e-01	6.37e-01	0.163000	-0.088600	-1.37e-01	5.27e-01	3.29e-01
Class B/2 (Secretin family receptors)	39	4.97e-01	6.37e-01	0.108000	0.051600	9.45e-02	5.78e-01	3.08e-01
RNA polymerase II transcribes snRNA genes	71	5.01e-01	6.42e-01	0.079700	-0.074800	-2.75e-02	2.76e-01	6.89e-01
Transport of Ribonucleoproteins into the Host Nucleus	31	5.03e-01	6.43e-01	0.123000	-0.030400	1.19e-01	7.69e-01	2.52e-01
Gluconeogenesis	27	5.03e-01	6.43e-01	0.129000	0.034800	1.24e-01	7.54e-01	2.64e-01
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	32	5.03e-01	6.43e-01	0.117000	-0.070400	-9.40e-02	4.91e-01	3.58e-01
HIV Life Cycle	143	5.04e-01	6.43e-01	0.056800	-0.056800	7.05e-04	2.42e-01	9.88e-01
PI-3K cascade:FGFR2	10	5.05e-01	6.43e-01	0.209000	-0.128000	-1.66e-01	4.84e-01	3.64e-01
Transcription of the HIV genome	67	5.05e-01	6.43e-01	0.081800	-0.078500	-2.30e-02	2.67e-01	7.45e-01
NRAGE signals death through JNK	48	5.09e-01	6.48e-01	0.096800	-0.096700	-3.27e-03	2.47e-01	9.69e-01
Metalloprotease DUBs	16	5.10e-01	6.48e-01	0.166000	0.048800	1.58e-01	7.35e-01	2.73e-01
Regulation of TP53 Degradation	34	5.11e-01	6.48e-01	0.113000	-0.085300	-7.35e-02	3.90e-01	4.58e-01
Regulation of TP53 Expression and Degradation	34	5.11e-01	6.48e-01	0.113000	-0.085300	-7.35e-02	3.90e-01	4.58e-01
Signaling by FGFR in disease	49	5.15e-01	6.53e-01	0.097000	-0.075400	6.11e-02	3.62e-01	4.60e-01
SUMOylation	162	5.17e-01	6.55e-01	0.052900	-0.050900	1.44e-02	2.65e-01	7.52e-01
Synthesis of glycosylphosphatidylinositol (GPI)	18	5.18e-01	6.56e-01	0.157000	0.154000	-3.21e-02	2.58e-01	8.13e-01
Trafficking of GluR2-containing AMPA receptors	10	5.21e-01	6.58e-01	0.205000	-0.180000	-9.88e-02	3.25e-01	5.88e-01
SUMOylation of DNA methylation proteins	16	5.21e-01	6.58e-01	0.162000	0.124000	1.04e-01	3.90e-01	4.73e-01
RAB GEFs exchange GTP for GDP on RABs	82	5.31e-01	6.70e-01	0.071500	-0.070500	-1.19e-02	2.71e-01	8.53e-01
Heme degradation	14	5.32e-01	6.70e-01	0.170000	0.130000	1.09e-01	3.98e-01	4.79e-01
Branched-chain amino acid catabolism	21	5.32e-01	6.70e-01	0.139000	0.065200	1.23e-01	6.05e-01	3.29e-01
VEGFR2 mediated cell proliferation	17	5.33e-01	6.70e-01	0.157000	-0.156000	-1.58e-02	2.66e-01	9.10e-01
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	11	5.33e-01	6.70e-01	0.196000	0.195000	-2.46e-02	2.64e-01	8.88e-01
Downstream signaling of activated FGFR1	20	5.34e-01	6.70e-01	0.142000	-0.119000	-7.70e-02	3.55e-01	5.51e-01
APC/C:Cdc20 mediated degradation of mitotic proteins	72	5.35e-01	6.71e-01	0.077700	-0.041200	6.58e-02	5.46e-01	3.35e-01
Transport of the SLBP independent Mature mRNA	34	5.37e-01	6.73e-01	0.111000	-0.000288	1.11e-01	9.98e-01	2.65e-01
Signaling by KIT in disease	19	5.39e-01	6.74e-01	0.146000	-0.141000	-3.82e-02	2.88e-01	7.73e-01
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	19	5.39e-01	6.74e-01	0.146000	-0.141000	-3.82e-02	2.88e-01	7.73e-01
RUNX2 regulates osteoblast differentiation	16	5.39e-01	6.74e-01	0.163000	0.070300	-1.47e-01	6.27e-01	3.09e-01
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	30	5.40e-01	6.74e-01	0.115000	0.062700	9.64e-02	5.52e-01	3.61e-01
Regulation of Glucokinase by Glucokinase Regulatory Protein	30	5.40e-01	6.74e-01	0.115000	0.062700	9.64e-02	5.52e-01	3.61e-01
Inflammasomes	18	5.41e-01	6.75e-01	0.152000	-0.020700	1.50e-01	8.79e-01	2.70e-01
NOD1/2 Signaling Pathway	31	5.42e-01	6.75e-01	0.117000	-0.107000	4.57e-02	3.02e-01	6.60e-01
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	73	5.43e-01	6.75e-01	0.076000	-0.031300	6.93e-02	6.44e-01	3.07e-01
G beta:gamma signalling through CDC42	11	5.43e-01	6.75e-01	0.196000	0.161000	-1.11e-01	3.54e-01	5.23e-01
Triglyceride biosynthesis	10	5.43e-01	6.75e-01	0.198000	0.127000	1.52e-01	4.87e-01	4.06e-01
DNA Damage/Telomere Stress Induced Senescence	28	5.46e-01	6.77e-01	0.118000	0.084500	8.21e-02	4.39e-01	4.52e-01
GABA receptor activation	29	5.48e-01	6.80e-01	0.119000	0.109000	-4.95e-02	3.12e-01	6.44e-01
E3 ubiquitin ligases ubiquitinate target proteins	44	5.49e-01	6.80e-01	0.096900	-0.039400	8.85e-02	6.52e-01	3.10e-01
Adherens junctions interactions	20	5.49e-01	6.80e-01	0.143000	0.137000	-3.87e-02	2.87e-01	7.65e-01
Signaling by Leptin	10	5.50e-01	6.80e-01	0.197000	0.179000	8.08e-02	3.26e-01	6.58e-01
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	13	5.52e-01	6.83e-01	0.171000	-0.091000	-1.45e-01	5.70e-01	3.65e-01
Deadenylation-dependent mRNA decay	55	5.54e-01	6.84e-01	0.086300	-0.074400	4.38e-02	3.40e-01	5.75e-01
PRC2 methylates histones and DNA	14	5.56e-01	6.86e-01	0.167000	0.167000	1.44e-03	2.79e-01	9.93e-01
Synthesis of PIPs at the Golgi membrane	15	5.58e-01	6.88e-01	0.158000	-0.134000	-8.44e-02	3.70e-01	5.72e-01
VxPx cargo-targeting to cilium	18	5.61e-01	6.91e-01	0.144000	-0.069000	-1.26e-01	6.12e-01	3.53e-01
Transcription of E2F targets under negative control by DREAM complex	19	5.70e-01	7.01e-01	0.138000	0.102000	9.31e-02	4.44e-01	4.82e-01
Interleukin-2 family signaling	29	5.71e-01	7.01e-01	0.116000	-0.056800	1.01e-01	5.97e-01	3.48e-01
Purine ribonucleoside monophosphate biosynthesis	11	5.71e-01	7.01e-01	0.187000	0.069400	-1.74e-01	6.90e-01	3.19e-01
Prolactin receptor signaling	11	5.71e-01	7.01e-01	0.181000	-0.081000	-1.62e-01	6.42e-01	3.51e-01
SUMO E3 ligases SUMOylate target proteins	156	5.75e-01	7.05e-01	0.049400	-0.047500	1.37e-02	3.07e-01	7.69e-01
Cytochrome c-mediated apoptotic response	13	5.76e-01	7.06e-01	0.171000	-0.077300	1.52e-01	6.29e-01	3.42e-01
Negative epigenetic regulation of rRNA expression	47	5.78e-01	7.07e-01	0.089600	-0.082700	3.43e-02	3.27e-01	6.84e-01
Tryptophan catabolism	10	5.78e-01	7.07e-01	0.189000	0.059900	1.79e-01	7.43e-01	3.27e-01
Telomere Extension By Telomerase	22	5.83e-01	7.12e-01	0.126000	0.099200	7.69e-02	4.20e-01	5.33e-01
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	71	5.83e-01	7.12e-01	0.072100	-0.068500	2.26e-02	3.19e-01	7.42e-01
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	19	5.85e-01	7.14e-01	0.135000	-0.119000	-6.32e-02	3.69e-01	6.33e-01
Signaling by NTRK3 (TRKC)	14	5.86e-01	7.14e-01	0.156000	-0.120000	-9.99e-02	4.36e-01	5.17e-01
Nuclear signaling by ERBB4	21	5.87e-01	7.15e-01	0.128000	-0.095600	-8.45e-02	4.49e-01	5.03e-01
Interferon Signaling	147	5.88e-01	7.15e-01	0.048900	0.012300	4.73e-02	7.98e-01	3.23e-01
Formation of the Early Elongation Complex	33	5.89e-01	7.15e-01	0.104000	-0.102000	2.14e-02	3.10e-01	8.32e-01
Formation of the HIV-1 Early Elongation Complex	33	5.89e-01	7.15e-01	0.104000	-0.102000	2.14e-02	3.10e-01	8.32e-01
BMAL1:CLOCK,NPAS2 activates circadian gene expression	25	5.93e-01	7.19e-01	0.120000	-0.069500	9.83e-02	5.48e-01	3.95e-01
Oncogene Induced Senescence	33	5.95e-01	7.21e-01	0.102000	0.002600	1.02e-01	9.79e-01	3.09e-01
Sealing of the nuclear envelope (NE) by ESCRT-III	25	5.95e-01	7.21e-01	0.120000	0.089300	-8.03e-02	4.40e-01	4.87e-01
Synthesis of PIPs at the late endosome membrane	10	5.98e-01	7.23e-01	0.182000	-0.149000	-1.04e-01	4.13e-01	5.71e-01
CRMPs in Sema3A signaling	12	5.98e-01	7.23e-01	0.166000	-0.131000	-1.01e-01	4.31e-01	5.44e-01
ADP signalling through P2Y purinoceptor 1	13	5.99e-01	7.23e-01	0.164000	0.158000	-4.25e-02	3.24e-01	7.91e-01
DNA Damage Recognition in GG-NER	38	6.01e-01	7.23e-01	0.096300	-0.084300	4.65e-02	3.69e-01	6.20e-01
Activation of G protein gated Potassium channels	14	6.01e-01	7.23e-01	0.159000	0.094200	-1.28e-01	5.42e-01	4.08e-01
G protein gated Potassium channels	14	6.01e-01	7.23e-01	0.159000	0.094200	-1.28e-01	5.42e-01	4.08e-01
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	14	6.01e-01	7.23e-01	0.159000	0.094200	-1.28e-01	5.42e-01	4.08e-01
Metabolism of cofactors	18	6.01e-01	7.23e-01	0.136000	0.133000	3.01e-02	3.30e-01	8.25e-01
Cell-cell junction organization	42	6.01e-01	7.23e-01	0.088400	0.076600	4.41e-02	3.91e-01	6.21e-01
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	13	6.05e-01	7.26e-01	0.161000	0.160000	-2.23e-02	3.18e-01	8.89e-01
Signaling by Retinoic Acid	33	6.06e-01	7.27e-01	0.100000	0.100000	8.17e-03	3.20e-01	9.35e-01
Metabolism of steroid hormones	23	6.07e-01	7.27e-01	0.123000	0.097800	-7.40e-02	4.17e-01	5.39e-01
Synaptic adhesion-like molecules	14	6.08e-01	7.27e-01	0.155000	0.151000	-3.57e-02	3.27e-01	8.17e-01
eNOS activation	10	6.08e-01	7.27e-01	0.183000	0.181000	-2.95e-02	3.22e-01	8.72e-01
NS1 Mediated Effects on Host Pathways	39	6.09e-01	7.27e-01	0.094000	-0.075200	5.64e-02	4.17e-01	5.42e-01
Mitotic G2-G2/M phases	177	6.09e-01	7.27e-01	0.043100	0.041600	1.10e-02	3.41e-01	8.00e-01
NOTCH2 Activation and Transmission of Signal to the Nucleus	18	6.15e-01	7.34e-01	0.132000	-0.117000	-6.09e-02	3.89e-01	6.55e-01
NoRC negatively regulates rRNA expression	44	6.17e-01	7.36e-01	0.086800	-0.080900	3.14e-02	3.54e-01	7.19e-01
RUNX2 regulates bone development	22	6.18e-01	7.36e-01	0.121000	0.014400	-1.20e-01	9.07e-01	3.28e-01
Thrombin signalling through proteinase activated receptors (PARs)	21	6.20e-01	7.38e-01	0.124000	-0.018100	1.23e-01	8.86e-01	3.31e-01
Sensory processing of sound	43	6.23e-01	7.41e-01	0.086800	-0.081000	3.14e-02	3.58e-01	7.22e-01
Glutamate Neurotransmitter Release Cycle	17	6.25e-01	7.42e-01	0.139000	-0.087500	1.07e-01	5.32e-01	4.43e-01
SHC-mediated cascade:FGFR2	10	6.27e-01	7.45e-01	0.174000	-0.167000	-4.89e-02	3.59e-01	7.89e-01
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	17	6.30e-01	7.47e-01	0.137000	-0.115000	7.41e-02	4.10e-01	5.97e-01
Ras activation upon Ca2+ influx through NMDA receptor	16	6.31e-01	7.47e-01	0.137000	-0.030900	-1.34e-01	8.30e-01	3.54e-01
STING mediated induction of host immune responses	10	6.32e-01	7.48e-01	0.172000	-0.112000	-1.30e-01	5.38e-01	4.78e-01
Purine catabolism	14	6.33e-01	7.48e-01	0.149000	0.145000	-3.50e-02	3.49e-01	8.21e-01
Xenobiotics	15	6.33e-01	7.48e-01	0.145000	0.127000	-6.95e-02	3.94e-01	6.41e-01
Nuclear import of Rev protein	33	6.36e-01	7.51e-01	0.097300	-0.046200	8.56e-02	6.46e-01	3.95e-01
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects	16	6.39e-01	7.54e-01	0.139000	0.071400	-1.19e-01	6.21e-01	4.09e-01
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	16	6.39e-01	7.54e-01	0.139000	0.071400	-1.19e-01	6.21e-01	4.09e-01
Detoxification of Reactive Oxygen Species	28	6.45e-01	7.60e-01	0.101000	-0.032300	-9.57e-02	7.67e-01	3.81e-01
mRNA Splicing - Minor Pathway	52	6.48e-01	7.62e-01	0.074500	-0.074200	-6.48e-03	3.55e-01	9.36e-01
Regulated Necrosis	47	6.48e-01	7.62e-01	0.079100	0.013400	-7.80e-02	8.73e-01	3.55e-01
Sensory perception of sweet, bitter, and umami (glutamate) taste	11	6.51e-01	7.65e-01	0.159000	0.055800	1.49e-01	7.49e-01	3.92e-01
Metabolism of porphyrins	25	6.56e-01	7.70e-01	0.104000	0.078500	6.81e-02	4.97e-01	5.55e-01
Pregnenolone biosynthesis	10	6.59e-01	7.73e-01	0.170000	0.136000	-1.02e-01	4.57e-01	5.77e-01
SLBP independent Processing of Histone Pre-mRNAs	10	6.64e-01	7.78e-01	0.168000	0.097500	-1.37e-01	5.94e-01	4.53e-01
Bile acid and bile salt metabolism	38	6.66e-01	7.80e-01	0.086000	-0.070900	4.87e-02	4.50e-01	6.03e-01
Regulation of APC/C activators between G1/S and early anaphase	77	6.67e-01	7.80e-01	0.060200	-0.055700	2.28e-02	3.99e-01	7.29e-01
Protein ubiquitination	64	6.68e-01	7.81e-01	0.065100	-0.064900	4.60e-03	3.69e-01	9.49e-01
Platelet Aggregation (Plug Formation)	24	6.70e-01	7.83e-01	0.107000	-0.065600	8.51e-02	5.78e-01	4.71e-01
Nucleotide catabolism	28	6.72e-01	7.84e-01	0.096600	0.019500	9.46e-02	8.58e-01	3.86e-01
Regulation of beta-cell development	27	6.75e-01	7.86e-01	0.096700	0.058800	7.68e-02	5.97e-01	4.90e-01
MASTL Facilitates Mitotic Progression	10	6.75e-01	7.86e-01	0.163000	-0.032500	1.60e-01	8.59e-01	3.82e-01
TP53 Regulates Transcription of Cell Cycle Genes	47	6.76e-01	7.86e-01	0.073300	0.043900	5.86e-02	6.03e-01	4.87e-01
RHO GTPases activate IQGAPs	11	6.80e-01	7.90e-01	0.156000	-0.097800	1.22e-01	5.74e-01	4.85e-01
Mitochondrial calcium ion transport	21	6.81e-01	7.91e-01	0.108000	-0.073600	-7.95e-02	5.59e-01	5.28e-01
Inhibition of DNA recombination at telomere	21	6.82e-01	7.92e-01	0.108000	0.055100	9.33e-02	6.62e-01	4.59e-01
G2/M Transition	175	6.82e-01	7.92e-01	0.037900	0.036300	1.11e-02	4.09e-01	8.00e-01
Signaling by FGFR2 in disease	30	6.84e-01	7.92e-01	0.090500	-0.080400	-4.15e-02	4.46e-01	6.94e-01
Senescence-Associated Secretory Phenotype (SASP)	49	6.85e-01	7.93e-01	0.073300	0.052400	-5.13e-02	5.26e-01	5.35e-01
HCMV Infection	82	6.85e-01	7.93e-01	0.055000	-0.052600	-1.59e-02	4.11e-01	8.03e-01
Muscle contraction	106	6.86e-01	7.93e-01	0.049800	-0.039800	2.99e-02	4.79e-01	5.96e-01
IL-6-type cytokine receptor ligand interactions	13	6.86e-01	7.93e-01	0.141000	-0.049300	1.32e-01	7.58e-01	4.11e-01
Norepinephrine Neurotransmitter Release Cycle	11	6.88e-01	7.94e-01	0.151000	-0.150000	1.76e-02	3.89e-01	9.20e-01
Intrinsic Pathway for Apoptosis	50	6.89e-01	7.95e-01	0.070400	-0.070400	-2.86e-03	3.90e-01	9.72e-01
EPHA-mediated growth cone collapse	15	6.91e-01	7.96e-01	0.131000	-0.099900	8.45e-02	5.03e-01	5.71e-01
PIWI-interacting RNA (piRNA) biogenesis	18	6.92e-01	7.97e-01	0.119000	-0.094600	7.21e-02	4.87e-01	5.96e-01
Anti-inflammatory response favouring Leishmania parasite infection	63	6.94e-01	7.98e-01	0.061400	-0.057000	-2.29e-02	4.35e-01	7.54e-01
Leishmania parasite growth and survival	63	6.94e-01	7.98e-01	0.061400	-0.057000	-2.29e-02	4.35e-01	7.54e-01
mRNA decay by 3’ to 5’ exoribonuclease	16	6.98e-01	8.02e-01	0.124000	0.111000	-5.52e-02	4.40e-01	7.03e-01
Activation of GABAB receptors	23	7.02e-01	8.03e-01	0.103000	0.082700	-6.19e-02	4.93e-01	6.07e-01
GABA B receptor activation	23	7.02e-01	8.03e-01	0.103000	0.082700	-6.19e-02	4.93e-01	6.07e-01
Inwardly rectifying K+ channels	17	7.02e-01	8.03e-01	0.120000	0.094300	-7.44e-02	5.01e-01	5.95e-01
Metabolism of folate and pterines	16	7.02e-01	8.03e-01	0.122000	-0.009830	1.21e-01	9.46e-01	4.01e-01
Signaling by SCF-KIT	37	7.03e-01	8.03e-01	0.079800	-0.079800	1.38e-03	4.01e-01	9.88e-01
Metabolism of non-coding RNA	52	7.03e-01	8.03e-01	0.066300	0.061100	2.59e-02	4.46e-01	7.47e-01
snRNP Assembly	52	7.03e-01	8.03e-01	0.066300	0.061100	2.59e-02	4.46e-01	7.47e-01
SUMOylation of RNA binding proteins	46	7.08e-01	8.07e-01	0.069500	0.043600	5.41e-02	6.09e-01	5.25e-01
Transcriptional Regulation by MECP2	45	7.08e-01	8.07e-01	0.071400	-0.071100	-6.40e-03	4.10e-01	9.41e-01
Downregulation of ERBB2 signaling	21	7.09e-01	8.07e-01	0.105000	-0.105000	6.46e-03	4.07e-01	9.59e-01
G-protein beta:gamma signalling	17	7.17e-01	8.16e-01	0.112000	-0.050500	-1.00e-01	7.18e-01	4.73e-01
Interleukin-35 Signalling	10	7.19e-01	8.17e-01	0.148000	-0.001970	1.48e-01	9.91e-01	4.17e-01
Caspase activation via extrinsic apoptotic signalling pathway	21	7.26e-01	8.25e-01	0.103000	-0.053800	8.74e-02	6.70e-01	4.88e-01
Signaling by NOTCH2	24	7.27e-01	8.25e-01	0.096000	-0.057500	7.68e-02	6.26e-01	5.15e-01
G alpha (12/13) signalling events	59	7.28e-01	8.26e-01	0.061100	-0.050200	3.48e-02	5.05e-01	6.44e-01
Diseases of carbohydrate metabolism	29	7.30e-01	8.27e-01	0.085100	-0.001650	8.51e-02	9.88e-01	4.28e-01
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	22	7.31e-01	8.27e-01	0.096300	-0.091300	-3.05e-02	4.59e-01	8.04e-01
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	17	7.31e-01	8.27e-01	0.109000	-0.034900	-1.04e-01	8.03e-01	4.59e-01
Meiotic synapsis	26	7.32e-01	8.27e-01	0.087800	0.070100	5.30e-02	5.36e-01	6.40e-01
Cytosolic iron-sulfur cluster assembly	11	7.33e-01	8.27e-01	0.140000	0.076100	-1.17e-01	6.62e-01	5.01e-01
GRB2:SOS provides linkage to MAPK signaling for Integrins	13	7.33e-01	8.27e-01	0.125000	0.118000	3.91e-02	4.60e-01	8.07e-01
RHO GTPases activate PKNs	31	7.34e-01	8.27e-01	0.080000	-0.055300	-5.78e-02	5.94e-01	5.77e-01
Activation of kainate receptors upon glutamate binding	16	7.35e-01	8.27e-01	0.113000	0.113000	1.34e-03	4.33e-01	9.93e-01
Sensory processing of sound by inner hair cells of the cochlea	39	7.35e-01	8.27e-01	0.073300	-0.070900	1.89e-02	4.44e-01	8.38e-01
Nucleotide Excision Repair	110	7.38e-01	8.30e-01	0.043800	0.038700	-2.04e-02	4.83e-01	7.11e-01
Integrin signaling	21	7.43e-01	8.34e-01	0.099100	-0.078000	6.10e-02	5.36e-01	6.28e-01
Non-integrin membrane-ECM interactions	37	7.43e-01	8.34e-01	0.071700	-0.051500	-4.99e-02	5.88e-01	6.00e-01
Defective Intrinsic Pathway for Apoptosis	23	7.44e-01	8.34e-01	0.094600	-0.070200	6.33e-02	5.60e-01	5.99e-01
TNFR1-induced NFkappaB signaling pathway	25	7.51e-01	8.42e-01	0.086100	-0.037400	-7.75e-02	7.46e-01	5.02e-01
Regulation of KIT signaling	15	7.53e-01	8.43e-01	0.111000	-0.103000	-4.13e-02	4.91e-01	7.82e-01
Generic Transcription Pathway	1024	7.54e-01	8.43e-01	0.013900	0.012700	5.51e-03	4.97e-01	7.68e-01
Formation of apoptosome	11	7.55e-01	8.43e-01	0.133000	-0.087400	1.00e-01	6.16e-01	5.64e-01
Regulation of the apoptosome activity	11	7.55e-01	8.43e-01	0.133000	-0.087400	1.00e-01	6.16e-01	5.64e-01
Switching of origins to a post-replicative state	87	7.55e-01	8.43e-01	0.047000	-0.013200	4.51e-02	8.32e-01	4.67e-01
Purine salvage	11	7.56e-01	8.43e-01	0.129000	0.127000	2.49e-02	4.67e-01	8.86e-01
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	18	7.56e-01	8.43e-01	0.100000	0.086300	5.06e-02	5.26e-01	7.10e-01
Condensation of Prophase Chromosomes	14	7.56e-01	8.43e-01	0.113000	0.099400	5.46e-02	5.20e-01	7.24e-01
ECM proteoglycans	32	7.61e-01	8.47e-01	0.076200	0.073400	-2.06e-02	4.73e-01	8.41e-01
SUMOylation of DNA damage response and repair proteins	76	7.62e-01	8.47e-01	0.049700	0.045300	-2.03e-02	4.95e-01	7.60e-01
Signaling by FGFR2 IIIa TM	17	7.63e-01	8.48e-01	0.102000	0.014800	1.01e-01	9.16e-01	4.70e-01
mRNA decay by 5’ to 3’ exoribonuclease	15	7.63e-01	8.48e-01	0.111000	-0.051900	9.86e-02	7.28e-01	5.09e-01
SUMOylation of chromatin organization proteins	55	7.64e-01	8.48e-01	0.058400	0.042400	-4.01e-02	5.86e-01	6.07e-01
Interleukin-27 signaling	10	7.68e-01	8.52e-01	0.133000	-0.010500	1.33e-01	9.54e-01	4.68e-01
NEP/NS2 Interacts with the Cellular Export Machinery	31	7.69e-01	8.52e-01	0.075600	-0.009340	7.50e-02	9.28e-01	4.70e-01
Metabolism of nitric oxide: NOS3 activation and regulation	13	7.71e-01	8.53e-01	0.117000	-0.039200	1.10e-01	8.07e-01	4.92e-01
Serotonin Neurotransmitter Release Cycle	10	7.73e-01	8.55e-01	0.131000	0.009340	1.30e-01	9.59e-01	4.76e-01
IRAK2 mediated activation of TAK1 complex	10	7.74e-01	8.55e-01	0.133000	-0.117000	6.25e-02	5.21e-01	7.32e-01
Gap-filling DNA repair synthesis and ligation in TC-NER	64	7.83e-01	8.64e-01	0.050300	0.005810	5.00e-02	9.36e-01	4.89e-01
Cyclin D associated events in G1	46	7.86e-01	8.66e-01	0.059500	0.007530	-5.90e-02	9.30e-01	4.89e-01
G1 Phase	46	7.86e-01	8.66e-01	0.059500	0.007530	-5.90e-02	9.30e-01	4.89e-01
Platelet homeostasis	48	7.89e-01	8.69e-01	0.058300	-0.024500	5.29e-02	7.69e-01	5.26e-01
Glycogen storage diseases	13	7.90e-01	8.69e-01	0.111000	0.105000	-3.76e-02	5.13e-01	8.14e-01
Regulation of innate immune responses to cytosolic DNA	11	7.91e-01	8.71e-01	0.121000	-0.044700	1.12e-01	7.98e-01	5.20e-01
Glycogen metabolism	25	7.94e-01	8.73e-01	0.077400	-0.026200	-7.28e-02	8.20e-01	5.29e-01
TNFR1-induced proapoptotic signaling	12	7.96e-01	8.74e-01	0.114000	0.046200	-1.04e-01	7.82e-01	5.31e-01
Regulation of FZD by ubiquitination	15	7.99e-01	8.77e-01	0.098100	-0.087100	-4.52e-02	5.59e-01	7.62e-01
RHO GTPases Activate NADPH Oxidases	16	8.01e-01	8.78e-01	0.094900	-0.089400	-3.20e-02	5.36e-01	8.25e-01
Keratan sulfate biosynthesis	20	8.03e-01	8.79e-01	0.085100	-0.084200	-1.21e-02	5.14e-01	9.25e-01
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	20	8.03e-01	8.79e-01	0.087100	-0.064900	5.81e-02	6.15e-01	6.53e-01
Class I peroxisomal membrane protein import	19	8.03e-01	8.79e-01	0.089400	0.061600	-6.48e-02	6.42e-01	6.25e-01
Signaling by CSF3 (G-CSF)	27	8.04e-01	8.79e-01	0.074700	-0.064400	3.80e-02	5.63e-01	7.33e-01
Platelet sensitization by LDL	15	8.06e-01	8.80e-01	0.097900	-0.097900	-2.87e-03	5.12e-01	9.85e-01
Dopamine Neurotransmitter Release Cycle	14	8.07e-01	8.80e-01	0.099200	0.060400	7.87e-02	6.96e-01	6.10e-01
Cargo trafficking to the periciliary membrane	47	8.07e-01	8.80e-01	0.054300	0.025700	4.78e-02	7.61e-01	5.71e-01
Viral Messenger RNA Synthesis	43	8.08e-01	8.81e-01	0.057800	-0.009050	5.71e-02	9.18e-01	5.17e-01
PECAM1 interactions	11	8.10e-01	8.82e-01	0.114000	0.035800	-1.09e-01	8.37e-01	5.33e-01
G-protein activation	11	8.12e-01	8.83e-01	0.113000	0.112000	-1.73e-02	5.21e-01	9.21e-01
Regulation of insulin secretion	47	8.14e-01	8.83e-01	0.053900	-0.004430	-5.37e-02	9.58e-01	5.24e-01
TRP channels	10	8.14e-01	8.83e-01	0.118000	0.015300	-1.17e-01	9.33e-01	5.23e-01
RNA Polymerase III Transcription Initiation From Type 3 Promoter	28	8.15e-01	8.83e-01	0.071200	-0.059300	3.94e-02	5.87e-01	7.19e-01
Activation of the AP-1 family of transcription factors	10	8.15e-01	8.83e-01	0.115000	-0.102000	-5.35e-02	5.78e-01	7.70e-01
TRAF6-mediated induction of TAK1 complex within TLR4 complex	14	8.18e-01	8.87e-01	0.099100	-0.091000	3.94e-02	5.56e-01	7.99e-01
RNA Polymerase I Transcription Initiation	44	8.21e-01	8.89e-01	0.054700	-0.054700	-6.34e-04	5.31e-01	9.94e-01
Interaction between L1 and Ankyrins	15	8.22e-01	8.89e-01	0.091500	-0.067000	-6.23e-02	6.53e-01	6.76e-01
HCMV Early Events	58	8.23e-01	8.90e-01	0.047600	-0.047100	7.21e-03	5.36e-01	9.24e-01
Cellular Senescence	124	8.26e-01	8.90e-01	0.032000	0.006580	3.13e-02	8.99e-01	5.48e-01
Signaling by ALK	20	8.26e-01	8.90e-01	0.081500	-0.062900	5.18e-02	6.26e-01	6.89e-01
RNA Pol II CTD phosphorylation and interaction with CE	27	8.27e-01	8.90e-01	0.070000	-0.049600	4.93e-02	6.55e-01	6.57e-01
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	27	8.27e-01	8.90e-01	0.070000	-0.049600	4.93e-02	6.55e-01	6.57e-01
Stimuli-sensing channels	59	8.27e-01	8.90e-01	0.046400	-0.046400	6.42e-04	5.38e-01	9.93e-01
Maturation of nucleoprotein	11	8.29e-01	8.92e-01	0.106000	0.105000	1.08e-02	5.45e-01	9.51e-01
Hyaluronan uptake and degradation	10	8.30e-01	8.92e-01	0.113000	-0.108000	3.29e-02	5.55e-01	8.57e-01
Triglyceride metabolism	22	8.32e-01	8.94e-01	0.074100	0.013700	7.28e-02	9.12e-01	5.55e-01
NCAM signaling for neurite out-growth	35	8.34e-01	8.95e-01	0.057700	0.037400	4.39e-02	7.02e-01	6.53e-01
mRNA Capping	29	8.35e-01	8.96e-01	0.065300	-0.025200	6.02e-02	8.15e-01	5.75e-01
Prefoldin mediated transfer of substrate to CCT/TriC	25	8.42e-01	9.02e-01	0.068000	-0.067700	6.73e-03	5.58e-01	9.54e-01
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	26	8.44e-01	9.04e-01	0.067000	-0.058300	3.31e-02	6.07e-01	7.70e-01
Regulation of IFNG signaling	13	8.48e-01	9.07e-01	0.092400	0.091800	-1.09e-02	5.67e-01	9.46e-01
Signaling by Activin	12	8.49e-01	9.07e-01	0.095900	-0.094800	1.47e-02	5.70e-01	9.30e-01
G beta:gamma signalling through PI3Kgamma	13	8.49e-01	9.07e-01	0.093000	0.042400	-8.28e-02	7.92e-01	6.06e-01
RIPK1-mediated regulated necrosis	27	8.52e-01	9.07e-01	0.061900	-0.054100	-3.00e-02	6.26e-01	7.87e-01
Regulation of necroptotic cell death	27	8.52e-01	9.07e-01	0.061900	-0.054100	-3.00e-02	6.26e-01	7.87e-01
Plasma lipoprotein assembly	17	8.52e-01	9.07e-01	0.079700	0.010300	-7.90e-02	9.42e-01	5.73e-01
Interactions of Rev with host cellular proteins	36	8.52e-01	9.07e-01	0.055500	-0.032600	4.50e-02	7.35e-01	6.41e-01
Export of Viral Ribonucleoproteins from Nucleus	32	8.56e-01	9.11e-01	0.056900	-0.001660	5.69e-02	9.87e-01	5.78e-01
Interferon gamma signaling	57	8.60e-01	9.14e-01	0.041300	0.031700	2.65e-02	6.79e-01	7.30e-01
Synthesis of PE	12	8.61e-01	9.14e-01	0.090900	0.005700	9.07e-02	9.73e-01	5.87e-01
Apoptotic factor-mediated response	18	8.61e-01	9.14e-01	0.073200	0.029200	6.72e-02	8.30e-01	6.22e-01
DCC mediated attractive signaling	12	8.62e-01	9.14e-01	0.092600	-0.078500	4.92e-02	6.38e-01	7.68e-01
Formation of the cornified envelope	21	8.64e-01	9.16e-01	0.069300	-0.059300	3.59e-02	6.38e-01	7.76e-01
G alpha (i) signalling events	121	8.66e-01	9.17e-01	0.028900	-0.018500	2.22e-02	7.26e-01	6.74e-01
Activation of SMO	14	8.69e-01	9.19e-01	0.083400	-0.071000	4.38e-02	6.46e-01	7.77e-01
Regulation of pyruvate dehydrogenase (PDH) complex	15	8.70e-01	9.20e-01	0.080100	0.040000	-6.93e-02	7.88e-01	6.42e-01
Transcriptional regulation of pluripotent stem cells	21	8.71e-01	9.21e-01	0.066000	0.003010	6.60e-02	9.81e-01	6.01e-01
Inactivation of CSF3 (G-CSF) signaling	22	8.78e-01	9.26e-01	0.061800	0.031300	5.33e-02	7.99e-01	6.65e-01
Glycogen synthesis	14	8.78e-01	9.26e-01	0.078500	-0.078300	-5.78e-03	6.12e-01	9.70e-01
Caspase activation via Death Receptors in the presence of ligand	13	8.80e-01	9.27e-01	0.081900	0.021500	-7.91e-02	8.93e-01	6.22e-01
Adrenaline,noradrenaline inhibits insulin secretion	15	8.80e-01	9.27e-01	0.076600	-0.037100	6.70e-02	8.04e-01	6.53e-01
TICAM1,TRAF6-dependent induction of TAK1 complex	10	8.82e-01	9.29e-01	0.089800	-0.051700	-7.34e-02	7.77e-01	6.88e-01
tRNA processing in the nucleus	54	8.88e-01	9.34e-01	0.037800	-0.033900	-1.67e-02	6.66e-01	8.32e-01
Triglyceride catabolism	12	8.89e-01	9.34e-01	0.081000	-0.080700	6.77e-03	6.28e-01	9.68e-01
Processing and activation of SUMO	10	8.89e-01	9.34e-01	0.089400	0.027500	-8.51e-02	8.80e-01	6.41e-01
Alpha-protein kinase 1 signaling pathway	11	8.90e-01	9.34e-01	0.084100	0.084000	-2.90e-03	6.29e-01	9.87e-01
RNA Polymerase I Transcription Termination	27	8.94e-01	9.38e-01	0.053700	-0.039000	3.69e-02	7.26e-01	7.40e-01
Negative regulators of DDX58/IFIH1 signaling	35	8.95e-01	9.38e-01	0.046900	-0.031200	3.50e-02	7.50e-01	7.20e-01
Notch-HLH transcription pathway	24	8.96e-01	9.38e-01	0.054500	-0.050000	-2.15e-02	6.71e-01	8.55e-01
Chemokine receptors bind chemokines	13	8.96e-01	9.38e-01	0.076300	-0.065500	3.92e-02	6.83e-01	8.07e-01
Integration of energy metabolism	73	8.97e-01	9.38e-01	0.031600	0.002940	-3.15e-02	9.65e-01	6.42e-01
Pyruvate metabolism	24	8.98e-01	9.39e-01	0.055200	0.052600	-1.67e-02	6.55e-01	8.88e-01
CASP8 activity is inhibited	10	9.02e-01	9.40e-01	0.082100	-0.018100	-8.01e-02	9.21e-01	6.61e-01
Dimerization of procaspase-8	10	9.02e-01	9.40e-01	0.082100	-0.018100	-8.01e-02	9.21e-01	6.61e-01
Regulation by c-FLIP	10	9.02e-01	9.40e-01	0.082100	-0.018100	-8.01e-02	9.21e-01	6.61e-01
G beta:gamma signalling through PLC beta	11	9.08e-01	9.45e-01	0.075300	0.068000	3.23e-02	6.96e-01	8.53e-01
Presynaptic function of Kainate receptors	11	9.08e-01	9.45e-01	0.075300	0.068000	3.23e-02	6.96e-01	8.53e-01
Assembly of the ORC complex at the origin of replication	10	9.13e-01	9.50e-01	0.077200	0.011600	7.64e-02	9.50e-01	6.76e-01
O-linked glycosylation of mucins	34	9.17e-01	9.52e-01	0.040800	0.013900	3.83e-02	8.88e-01	6.99e-01
Signal amplification	19	9.17e-01	9.52e-01	0.055800	-0.053300	1.63e-02	6.87e-01	9.02e-01
Ca2+ pathway	44	9.18e-01	9.52e-01	0.035800	0.035300	6.17e-03	6.86e-01	9.44e-01
Protein folding	78	9.24e-01	9.58e-01	0.026700	0.020600	-1.69e-02	7.53e-01	7.97e-01
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	13	9.28e-01	9.61e-01	0.062800	-0.054800	3.07e-02	7.32e-01	8.48e-01
G alpha (z) signalling events	25	9.29e-01	9.61e-01	0.044100	-0.043300	-8.58e-03	7.08e-01	9.41e-01
DNA Double Strand Break Response	40	9.29e-01	9.62e-01	0.035300	-0.034100	8.91e-03	7.09e-01	9.22e-01
Processing of Capped Intronless Pre-mRNA	28	9.34e-01	9.66e-01	0.039600	-0.019400	-3.45e-02	8.59e-01	7.52e-01
RMTs methylate histone arginines	30	9.35e-01	9.66e-01	0.039500	0.027000	-2.88e-02	7.98e-01	7.85e-01
ADORA2B mediated anti-inflammatory cytokines production	42	9.36e-01	9.66e-01	0.033100	0.027100	-1.90e-02	7.61e-01	8.31e-01
Transcription-Coupled Nucleotide Excision Repair (TC-NER)	78	9.36e-01	9.66e-01	0.024100	-0.022800	7.68e-03	7.28e-01	9.07e-01
Rev-mediated nuclear export of HIV RNA	34	9.38e-01	9.66e-01	0.035500	0.000584	3.55e-02	9.95e-01	7.20e-01
SUMOylation of ubiquitinylation proteins	38	9.38e-01	9.66e-01	0.033200	-0.031800	-9.50e-03	7.35e-01	9.19e-01
RNA Polymerase I Promoter Clearance	48	9.42e-01	9.66e-01	0.029100	-0.028600	5.55e-03	7.32e-01	9.47e-01
RNA Polymerase I Transcription	48	9.42e-01	9.66e-01	0.029100	-0.028600	5.55e-03	7.32e-01	9.47e-01
Transcriptional Regulation by E2F6	34	9.42e-01	9.66e-01	0.034100	0.033900	4.14e-03	7.33e-01	9.67e-01
APC/C-mediated degradation of cell cycle proteins	84	9.42e-01	9.66e-01	0.022200	-0.008930	2.03e-02	8.88e-01	7.48e-01
Regulation of mitotic cell cycle	84	9.42e-01	9.66e-01	0.022200	-0.008930	2.03e-02	8.88e-01	7.48e-01
Regulation of MECP2 expression and activity	29	9.46e-01	9.66e-01	0.036500	-0.029700	2.12e-02	7.82e-01	8.43e-01
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding	27	9.47e-01	9.66e-01	0.037400	-0.034200	1.50e-02	7.58e-01	8.93e-01
Processing of SMDT1	15	9.48e-01	9.66e-01	0.049300	-0.048200	1.03e-02	7.47e-01	9.45e-01
Downregulation of ERBB2:ERBB3 signaling	10	9.48e-01	9.66e-01	0.060000	-0.059100	1.07e-02	7.46e-01	9.53e-01
Surfactant metabolism	14	9.48e-01	9.66e-01	0.051300	0.041200	-3.06e-02	7.89e-01	8.43e-01
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	11	9.50e-01	9.66e-01	0.055900	0.010300	-5.49e-02	9.53e-01	7.52e-01
Gene expression (Transcription)	1265	9.50e-01	9.66e-01	0.005330	-0.004840	-2.23e-03	7.76e-01	8.96e-01
HIV Transcription Initiation	45	9.51e-01	9.66e-01	0.027200	-0.007060	-2.62e-02	9.35e-01	7.61e-01
RNA Polymerase II HIV Promoter Escape	45	9.51e-01	9.66e-01	0.027200	-0.007060	-2.62e-02	9.35e-01	7.61e-01
RNA Polymerase II Promoter Escape	45	9.51e-01	9.66e-01	0.027200	-0.007060	-2.62e-02	9.35e-01	7.61e-01
RNA Polymerase II Transcription Initiation	45	9.51e-01	9.66e-01	0.027200	-0.007060	-2.62e-02	9.35e-01	7.61e-01
RNA Polymerase II Transcription Initiation And Promoter Clearance	45	9.51e-01	9.66e-01	0.027200	-0.007060	-2.62e-02	9.35e-01	7.61e-01
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	45	9.51e-01	9.66e-01	0.027200	-0.007060	-2.62e-02	9.35e-01	7.61e-01
Factors involved in megakaryocyte development and platelet production	103	9.60e-01	9.75e-01	0.016000	0.010600	1.21e-02	8.53e-01	8.33e-01
HuR (ELAVL1) binds and stabilizes mRNA	10	9.62e-01	9.76e-01	0.051500	-0.023800	4.56e-02	8.96e-01	8.03e-01
Dual incision in TC-NER	65	9.65e-01	9.78e-01	0.019300	-0.005910	1.84e-02	9.34e-01	7.98e-01
SUMOylation of SUMOylation proteins	34	9.65e-01	9.78e-01	0.026000	0.006730	2.51e-02	9.46e-01	8.00e-01
Thromboxane signalling through TP receptor	14	9.69e-01	9.81e-01	0.039200	-0.019400	3.41e-02	9.00e-01	8.25e-01
Regulation of TP53 Activity	152	9.69e-01	9.81e-01	0.011500	-0.009970	-5.82e-03	8.32e-01	9.02e-01
Regulation of TP53 Activity through Association with Co-factors	11	9.72e-01	9.82e-01	0.040700	-0.014700	-3.79e-02	9.33e-01	8.28e-01
Sensory processing of sound by outer hair cells of the cochlea	31	9.72e-01	9.82e-01	0.024700	0.005820	-2.41e-02	9.55e-01	8.17e-01
RNA Polymerase I Promoter Escape	29	9.74e-01	9.83e-01	0.024900	-0.022500	1.07e-02	8.34e-01	9.21e-01
Formation of tubulin folding intermediates by CCT/TriC	20	9.76e-01	9.85e-01	0.027800	-0.026200	-9.44e-03	8.39e-01	9.42e-01
Defects in vitamin and cofactor metabolism	20	9.77e-01	9.85e-01	0.028300	-0.007500	2.73e-02	9.54e-01	8.33e-01
FGFR2 mutant receptor activation	20	9.78e-01	9.85e-01	0.027200	-0.000820	2.72e-02	9.95e-01	8.33e-01
ADP signalling through P2Y purinoceptor 12	12	9.79e-01	9.86e-01	0.034000	0.033400	6.27e-03	8.41e-01	9.70e-01
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	39	9.80e-01	9.86e-01	0.018400	-0.018400	5.06e-04	8.42e-01	9.96e-01
Heme biosynthesis	13	9.81e-01	9.86e-01	0.032300	0.016700	-2.77e-02	9.17e-01	8.63e-01
Protein methylation	15	9.82e-01	9.87e-01	0.028700	0.021900	-1.85e-02	8.83e-01	9.01e-01
Smooth Muscle Contraction	28	9.85e-01	9.89e-01	0.019400	-0.015100	1.22e-02	8.90e-01	9.11e-01
HCMV Late Events	55	9.90e-01	9.93e-01	0.010600	-0.009220	-5.31e-03	9.06e-01	9.46e-01
Cellular hexose transport	16	9.91e-01	9.93e-01	0.019100	-0.013500	-1.36e-02	9.26e-01	9.25e-01
Chaperonin-mediated protein folding	72	9.98e-01	1.00e+00	0.003950	0.000811	-3.86e-03	9.91e-01	9.55e-01
RNA Polymerase II Transcription	1142	9.99e-01	1.00e+00	0.000574	-0.000350	-4.55e-04	9.84e-01	9.80e-01
Processing of Intronless Pre-mRNAs	19	1.00e+00	1.00e+00	0.003750	-0.002490	2.81e-03	9.85e-01	9.83e-01

---

Detailed Gene set reports

Cellular responses to stimuli

Cellular responses to stimuli

metric	value
setSize	641
pMANOVA	2.71e-23
p.adjustMANOVA	3.73e-20
s.dist	0.241
s.x	-0.222
s.abs	0.092
p.x	1.36e-21
p.abs	7.93e-05

Top 20 genes

Gene	x	abs
HSPA5	-7144	14531
CALR	-7142	14529
DNAJB11	-7141	14528
HYOU1	-7140	14527
HERPUD1	-7137	14524
DNAJC3	-7131	14516
HSP90B1	-7129	14514
DNAJB9	-7125	14510
SYVN1	-7108	14485
PDIA6	-7106	14482
EDEM1	-7103	14479
WFS1	-7096	14466
ATP6V0B	-7064	14422
CSRP1	-7054	14410
GFPT1	-7051	14406
DDIT3	-7047	14401
EIF2AK3	-7028	14371
HM13	-7025	14368
FLCN	-7022	14362
RRAGC	-7009	14345

Click HERE to show all gene set members

All member genes

	x	abs
AAAS	2965	5701
ABCC1	-5950	12501
ACADVL	4157	7903
ACD	3041	5857
ACTR10	5570	10590
ACTR1A	-5162	10903
ADD1	-5966	12538
AGO1	4307	8173
AGO3	-5803	12205
AGO4	6581	12561
AJUBA	6013	11454
AKT1S1	-5990	12584
ALB	3096	5965
ANAPC1	1998	3900
ANAPC10	6071	11551
ANAPC11	-1544	3134
ANAPC15	-4945	10442
ANAPC16	6307	12018
ANAPC2	-1639	3349
ANAPC4	305	595
ANAPC5	3942	7485
ANAPC7	6249	11895
APOA1	6993	13433
APOB	-2964	6172
AQP8	-5439	11449
ARFGAP1	-1587	3224
ARNT	1014	1996
ARNTL	-359	732
ASF1A	3905	7415
ASNS	6208	11814
ATF2	-6175	12933
ATF3	2488	4803
ATF4	-5664	11932
ATF5	-6830	14076
ATF6	-6949	14261
ATM	1503	2965
ATOX1	3659	6974
ATP6V0B	-7064	14422
ATP6V0C	-6086	12764
ATP6V0D1	-6908	14206
ATP6V0D2	747	1494
ATP6V0E1	-6622	13731
ATP6V0E2	5683	10798
ATP6V1A	-3777	7965
ATP6V1B1	4549	8635
ATP6V1B2	-5574	11744
ATP6V1C1	-4946	10444
ATP6V1C2	-5929	12453
ATP6V1D	-6922	14228
ATP6V1E1	-6271	13114
ATP6V1E2	-534	1090
ATP6V1F	-868	1771
ATP6V1G1	-5352	11283
ATP6V1G2	690	1360
ATP6V1H	-4423	9358
ATP7A	2111	4123
ATR	5478	10396
BACH1	-4970	10478
BAG1	-4540	9631
BAG2	1269	2521
BAG3	-5335	11246
BAG4	4019	7633
BAG5	-5238	11071
BLVRA	-1440	2921
BLVRB	811	1602
BMI1	-4180	8838
BMT2	638	1250
CA9	-5494	11579
CABIN1	-2162	4476
CALR	-7142	14529
CAMK2A	4566	8669
CAMK2D	1711	3358
CAMK2G	2145	4176
CAPZA1	-4855	10272
CAPZA2	-1549	3143
CAPZB	-1169	2376
CARM1	3517	6725
CAT	5018	9504
CBX2	6958	13350
CBX4	-4063	8580
CBX6	2911	5608
CBX8	-4370	9242
CCAR2	-3268	6864
CCNA2	6594	12587
CCNE1	2754	5315
CCNE2	-2024	4152
CCS	4860	9214
CDC16	1175	2309
CDC23	6113	11639
CDC26	-197	402
CDC27	-1529	3103
CDK2	4114	7809
CDK4	-5064	10698
CDK6	4754	9023
CDKN1A	-3580	7569
CDKN1B	-786	1590
CDKN2A	3704	7056
CDKN2B	1710	3352
CDKN2C	4232	8034
CDKN2D	-4869	10296
CEBPB	-1129	2300
CEBPG	-5987	12578
CHAC1	6845	13119
CHD9	-4634	9842
CITED2	4227	8029
CLOCK	-1648	3360
COL4A6	5592	10629
COX11	1523	3007
COX14	-4004	8475
COX16	-910	1851
COX18	3788	7215
COX19	4126	7838
COX20	-6555	13633
COX4I1	-4038	8531
COX5A	-5033	10625
COX5B	704	1393
COX6A1	-3107	6487
COX6B1	-3158	6617
COX6C	344	661
COX7A2L	-4360	9228
COX7B	-3866	8175
COX7C	1483	2931
COX8A	-4517	9591
CREB1	474	935
CREB3	-3650	7725
CREB3L2	-6832	14080
CREB3L3	5999	11433
CREB3L4	5920	11259
CREBBP	-3888	8214
CREBRF	-4582	9731
CRTC1	2969	5705
CRTC2	-6651	13780
CRTC3	-4964	10469
CRYAB	939	1848
CSNK2A1	-5040	10637
CSNK2A2	-4546	9641
CSNK2B	4415	8368
CSRP1	-7054	14410
CTDSP2	-4462	9444
CUL1	-4129	8725
CUL2	359	703
CUL3	-3056	6363
CUL7	4377	8310
CXCL8	3625	6916
CXXC1	-6033	12670
CYBA	2202	4283
CYCS	562	1098
DCP2	-5125	10825
DCTN1	-1635	3338
DCTN2	-3957	8375
DCTN3	1457	2887
DCTN4	-1937	3979
DCTN5	-3634	7690
DCTN6	-318	666
DDIT3	-7047	14401
DDX11	6254	11907
DEDD2	-3679	7779
DEPDC5	-4989	10518
DIS3	-1573	3190
DNAJA1	-2311	4793
DNAJA2	-3258	6843
DNAJB1	-6326	13228
DNAJB11	-7141	14528
DNAJB6	-5140	10856
DNAJB9	-7125	14510
DNAJC2	-4791	10157
DNAJC3	-7131	14516
DNAJC7	-6489	13527
DYNC1H1	-3614	7639
DYNC1I2	-2780	5783
DYNC1LI1	-2519	5237
DYNC1LI2	-3897	8235
DYNLL1	2509	4853
DYNLL2	6044	11507
E2F1	7096	13694
E2F2	6426	12251
E2F3	444	876
EDEM1	-7103	14479
EED	2369	4581
EEF1A1	-4138	8740
EGLN1	-4303	9096
EGLN2	-6763	13975
EGLN3	2588	5001
EHMT1	-1678	3422
EHMT2	400	784
EIF2AK1	-2921	6069
EIF2AK3	-7028	14371
EIF2AK4	-1455	2950
EIF2S1	-5190	10961
EIF2S2	-4458	9437
EIF2S3	-3669	7757
ELOB	-3004	6272
ELOC	645	1265
EP300	-6470	13485
EP400	-3754	7921
EPAS1	-4915	10387
EPO	2073	4044
ERF	-6016	12637
ERN1	-6872	14152
ERO1A	-198	403
ETS1	3554	6791
ETS2	-2186	4533
EXOSC1	3486	6667
EXOSC2	3779	7192
EXOSC3	-3453	7270
EXOSC4	3220	6193
EXOSC5	-4766	10117
EXOSC6	-6503	13547
EXOSC7	5196	9819
EXOSC8	472	928
EXOSC9	3293	6333
EXTL1	6941	13312
EXTL2	3353	6440
EXTL3	3575	6822
EZH2	-5631	11860
FABP1	5092	9636
FAU	-4990	10520
FBXL17	-4348	9200
FKBP14	-6896	14184
FKBP4	-5807	12213
FKBP5	5342	10097
FLCN	-7022	14362
FNIP1	-6782	13998
FNIP2	-5498	11587
FOS	-5174	10931
FZR1	201	397
GCN1	-4627	9826
GFPT1	-7051	14406
GOSR2	1238	2441
GPX1	3161	6089
GPX2	-6408	13379
GPX3	5394	10217
GPX7	2739	5287
GPX8	743	1486
GRB10	-5504	11598
GSK3A	-3684	7787
GSK3B	-5101	10767
GSR	-3534	7463
H2AFX	5356	10131
HBA1	-3024	6302
HDAC3	38	84
HDAC6	5953	11333
HDGF	-6715	13896
HELZ2	4786	9086
HERPUD1	-7137	14524
HIF1A	-4165	8807
HIF1AN	4302	8161
HIF3A	4444	8437
HIGD1A	720	1427
HIKESHI	6144	11695
HIRA	-6076	12746
HM13	-7025	14368
HMGA1	-5226	11043
HMGA2	5643	10714
HMOX1	4592	8715
HMOX2	-4742	10061
HSBP1	1372	2726
HSF1	-2414	5003
HSP90AA1	-1030	2096
HSP90AB1	-4426	9363
HSP90B1	-7129	14514
HSPA12A	5480	10402
HSPA13	-6786	14005
HSPA14	-5393	11362
HSPA1A	1835	3603
HSPA2	3418	6538
HSPA4	925	1816
HSPA4L	3936	7475
HSPA5	-7144	14531
HSPA6	-3353	7061
HSPA8	-4654	9895
HSPA9	-6580	13667
HSPB8	-5506	11600
HSPH1	-6524	13584
HYOU1	-7140	14527
ID1	4484	8511
IGFBP1	-3931	8301
IGFBP7	4272	8108
IMPACT	4432	8414
ITFG2	2143	4172
JUN	-2934	6103
KAT5	1580	3115
KDELR3	976	1922
KDM6B	-6944	14253
KEAP1	-6482	13510
KHSRP	-994	2029
KLHDC3	-3802	8036
KPTN	4478	8495
LAMTOR1	-774	1557
LAMTOR2	-148	299
LAMTOR3	-2631	5467
LAMTOR4	1834	3602
LAMTOR5	-5293	11181
LIMD1	2987	5738
LMNA	-3717	7854
LMNB1	7101	13707
LRPPRC	-5756	12122
LY96	-1339	2689
MAFK	-6985	14318
MAP2K3	-3342	7038
MAP2K4	-4505	9558
MAP2K6	-2351	4868
MAP2K7	-4399	9311
MAP4K4	-5792	12181
MAPK1	-5066	10705
MAPK10	2952	5681
MAPK11	251	492
MAPK14	2269	4391
MAPK3	6640	12684
MAPK7	-4382	9270
MAPK8	-700	1418
MAPK9	1760	3449
MAPKAPK2	-6461	13468
MAPKAPK3	-5773	12147
MAPKAPK5	-4050	8556
MBTPS1	-5958	12523
MBTPS2	3687	7019
MDM2	-956	1942
MDM4	-2561	5318
MED1	-5451	11468
MEF2D	-5995	12594
MINK1	2261	4372
MIOS	2912	5610
MLST8	1875	3677
MOV10	6408	12217
MRE11	4100	7780
MRPL18	-882	1806
MT-CO1	6493	12380
MT-CO2	716	1414
MT-CO3	7316	14274
MT1A	-309	643
MT1E	-4931	10415
MT1F	-6694	13868
MT1G	-6753	13955
MT1X	-4230	8940
MT2A	-1121	2284
MTF1	-3947	8354
MTOR	-3683	7785
MYDGF	-6976	14306
NBN	4533	8606
NCF2	-5438	11446
NCOA1	-4665	9914
NCOA2	4780	9072
NCOA6	-6745	13941
NCOR1	-4374	9256
NCOR2	-4409	9331
NDC1	-1490	3023
NDUFA4	-390	795
NFE2L2	-2108	4363
NFKB1	-3507	7409
NFYA	-2482	5142
NFYB	5091	9634
NFYC	-690	1395
NPAS2	-5410	11394
NPRL2	4876	9247
NPRL3	4164	7917
NR1D1	-4622	9818
NR3C1	-4005	8476
NR3C2	1520	2999
NRIP1	570	1114
NUDT2	301	589
NUP107	6076	11561
NUP133	1362	2708
NUP153	2712	5230
NUP155	4796	9102
NUP160	-329	683
NUP188	-4991	10521
NUP205	-5275	11144
NUP210	6802	13025
NUP214	-1926	3957
NUP35	5982	11387
NUP37	7100	13706
NUP43	2808	5410
NUP50	-4733	10047
NUP54	3310	6371
NUP58	2380	4603
NUP62	-299	618
NUP85	4178	7946
NUP88	-4777	10134
NUP93	5831	11067
NUP98	-3764	7940
P4HB	-6884	14170
PARN	-4578	9715
PDIA5	579	1130
PDIA6	-7106	14482
PHC1	-4280	9053
PHC2	3713	7072
PHC3	843	1660
PLA2G4B	4716	8953
POM121	-6353	13281
POM121C	-6045	12687
POT1	6132	11678
PPARA	-6722	13906
PPARGC1A	-5869	12350
PPP1R15A	-6783	13999
PPP2R5B	-5131	10834
PRDX1	-6673	13828
PRDX2	-961	1951
PRDX3	165	321
PRDX5	-1274	2560
PRDX6	-54	106
PREB	1446	2868
PRKCD	-5638	11872
PSMA1	-5730	12052
PSMA2	-5801	12203
PSMA3	-3078	6422
PSMA4	-4211	8902
PSMA5	-2715	5657
PSMA6	-126	261
PSMA7	-892	1820
PSMB1	1054	2062
PSMB10	423	838
PSMB2	1876	3678
PSMB3	-1915	3928
PSMB4	-1144	2330
PSMB5	-742	1484
PSMB6	-4888	10326
PSMB7	-4372	9253
PSMB9	5491	10430
PSMC1	-5564	11724
PSMC2	-2389	4948
PSMC3	-1509	3070
PSMC4	-4808	10196
PSMC5	-4091	8646
PSMC6	-4878	10307
PSMD1	-5351	11280
PSMD10	4933	9356
PSMD11	-432	879
PSMD12	4303	8163
PSMD13	-2577	5353
PSMD14	5974	11371
PSMD2	-6435	13423
PSMD3	-5535	11655
PSMD4	4567	8670
PSMD5	5116	9676
PSMD6	-5951	12502
PSMD7	4942	9371
PSMD8	-2928	6091
PSMD9	-4638	9853
PSME1	-2348	4861
PSME2	-5481	11555
PSME3	-3813	8052
PSME4	-6450	13450
PSMF1	-6663	13810
PTGES3	3734	7103
PTK6	3304	6358
RAD50	-4078	8623
RAE1	4394	8335
RAI1	-2008	4118
RANBP2	-4	9
RB1	470	925
RBBP4	-3297	6938
RBBP7	5134	9712
RBX1	-3714	7850
RELA	-2632	5468
RHEB	-3762	7936
RING1	4067	7710
RNF2	2454	4732
RORA	-5875	12360
RPA1	-5008	10563
RPA2	6961	13354
RPA3	6375	12149
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS19BP1	-6915	14217
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS6KA1	-3857	8159
RPS6KA2	-1149	2339
RPS6KA3	-3030	6316
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
RPTOR	407	803
RRAGA	2609	5038
RRAGB	-4819	10211
RRAGC	-7009	14345
RRAGD	-6743	13938
RXRA	-4073	8607
SCMH1	6656	12722
SCO1	-3018	6294
SCO2	-6638	13759
SEC13	-6812	14049
SEC31A	-5766	12138
SEH1L	-4472	9474
SEM1	-3130	6566
SERP1	-6964	14288
SERPINH1	-3945	8349
SESN1	4963	9414
SESN2	-6610	13712
SH3BP4	-3331	7014
SHC1	-6910	14209
SIN3A	-5884	12373
SIN3B	4029	7646
SIRT1	-5628	11855
SKP1	-544	1117
SKP2	5946	11323
SLC38A9	-5539	11664
SLC46A1	-835	1702
SMARCD3	2305	4455
SOD1	5779	10975
SOD2	7342	14367
SP1	-5412	11396
SRPRA	-4802	10175
SRPRB	-6893	14181
SSR1	-6907	14205
ST13	-4320	9142
STAP2	4664	8852
STAT3	4253	8078
STIP1	-3571	7550
SULT1A3	1040	2038
SURF1	327	631
SUZ12	346	664
SYVN1	-7108	14485
SZT2	5052	9557
TACO1	5527	10511
TATDN2	-6467	13480
TBL1X	-1621	3308
TBL1XR1	1404	2795
TCIRG1	180	348
TERF1	-5276	11145
TERF2	4479	8496
TERF2IP	-4282	9056
TFDP1	-2579	5361
TFDP2	4856	9210
TGS1	2148	4181
TINF2	4357	8275
TLN1	-6146	12872
TNFRSF21	-2173	4491
TNIK	4872	9243
TNRC6A	1824	3580
TNRC6B	-4212	8904
TNRC6C	-4805	10180
TP53	-2020	4144
TPP1	-6407	13378
TPR	565	1105
TRIB3	-6798	14029
TSPYL2	-6784	14002
TXN	-3611	7626
TXN2	-243	499
TXNIP	7384	14509
TXNRD1	-6806	14041
TXNRD2	308	603
UBA52	-5068	10707
UBB	-4263	9013
UBC	779	1551
UBE2C	7137	13793
UBE2D1	3523	6734
UBE2D2	-913	1857
UBE2D3	-3997	8449
UBE2E1	3733	7102
UBE2S	-1872	3839
UBN1	-5851	12306
VCP	-6720	13902
VEGFA	-4456	9433
VHL	-6491	13531
WDR24	4466	8468
WDR59	4915	9316
WFS1	-7096	14466
WIPI1	-6942	14251
WTIP	4170	7931
XBP1	5937	11302
XPO1	-1864	3824
YIF1A	195	381
YWHAE	129	253
ZBTB17	-3194	6703

---

---

Asparagine N-linked glycosylation

Asparagine N-linked glycosylation

metric	value
setSize	252
pMANOVA	2.39e-22
p.adjustMANOVA	1.64e-19
s.dist	0.372
s.x	-0.306
s.abs	0.212
p.x	6.7e-17
p.abs	7.65e-09

Top 20 genes

Gene	x	abs
CALR	-7142	14529
SEC24D	-7134	14520
SEL1L	-7124	14508
SYVN1	-7108	14485
EDEM1	-7103	14479
CANX	-7092	14462
PDIA3	-7086	14454
SLC17A5	-7072	14434
TMED2	-7071	14433
MCFD2	-7065	14425
GFPT1	-7051	14406
MIA3	-7049	14404
DERL2	-7046	14399
MAGT1	-7045	14398
RPN1	-7013	14350
FUT3	-7001	14335
OS9	-6986	14320
UGGT1	-6954	14270
TMED7	-6933	14240
NANS	-6906	14204

Click HERE to show all gene set members

All member genes

	x	abs
ACTR10	5570	10590
ACTR1A	-5162	10903
ALG1	-4352	9207
ALG10	2654	5133
ALG10B	5899	11213
ALG11	-5957	12520
ALG12	-6081	12752
ALG13	1348	2687
ALG14	-3206	6723
ALG2	-6554	13631
ALG3	-6601	13700
ALG5	-6471	13488
ALG6	4943	9374
ALG8	1117	2188
ALG9	-426	865
AMDHD2	5414	10267
AMFR	-2698	5612
ANK1	-4656	9901
ANK2	-6778	13993
ANK3	303	591
ANKRD28	4146	7882
ARCN1	-6505	13549
AREG	-4847	10258
ARF1	-6021	12642
ARF3	-2430	5040
ARF4	-5812	12225
ARF5	4743	8998
ARFGAP1	-1587	3224
ARFGAP2	1283	2547
ARFGAP3	-4817	10209
ASGR1	-1889	3870
ASGR2	-2985	6225
B4GALNT2	1387	2758
B4GALT1	-262	540
B4GALT2	-2487	5152
B4GALT3	-4852	10265
B4GALT4	2602	5027
B4GALT5	6846	13121
B4GALT6	2881	5555
BET1	457	896
BET1L	3487	6669
CALR	-7142	14529
CANX	-7092	14462
CAPZA1	-4855	10272
CAPZA2	-1549	3143
CAPZB	-1169	2376
CD55	-6517	13575
CD59	-3245	6818
CHST10	6919	13262
CMAS	5724	10871
CNIH1	212	416
CNIH3	-1958	4025
COG1	4586	8708
COG2	-4254	8997
COG3	-5948	12497
COG4	1972	3852
COG5	-3964	8389
COG6	3264	6266
COG7	4792	9093
COG8	6745	12910
COL7A1	5362	10152
COPA	-3958	8376
COPB1	-4098	8664
COPB2	-6532	13594
COPE	-5961	12527
COPG1	-5135	10840
COPG2	6142	11691
COPZ1	782	1554
CSNK1D	-5722	12038
CTSA	-6288	13149
CTSC	-4446	9398
DAD1	-6240	13053
DCTN1	-1635	3338
DCTN2	-3957	8375
DCTN3	1457	2887
DCTN4	-1937	3979
DCTN5	-3634	7690
DCTN6	-318	666
DDOST	-6429	13410
DERL1	-6423	13398
DERL2	-7046	14399
DHDDS	2399	4636
DOLK	108	213
DOLPP1	-4988	10517
DPAGT1	-6046	12688
DPM1	-1233	2494
DPM2	-2111	4373
DPM3	3217	6189
DYNC1H1	-3614	7639
DYNC1I2	-2780	5783
DYNC1LI1	-2519	5237
DYNC1LI2	-3897	8235
DYNLL1	2509	4853
DYNLL2	6044	11507
EDEM1	-7103	14479
EDEM2	-5520	11628
EDEM3	-1903	3904
ENGASE	6457	12309
F5	831	1638
F8	735	1460
FPGT	5627	10685
FUCA1	2696	5210
FUOM	2573	4976
FUT3	-7001	14335
FUT8	-5134	10839
GANAB	2813	5417
GBF1	-4981	10507
GFPT1	-7051	14406
GLB1	1557	3064
GMDS	-3350	7053
GMPPA	-6346	13267
GMPPB	-6844	14096
GNE	6051	11517
GNPNAT1	2394	4628
GOLGA2	-5310	11209
GOLGB1	-3498	7386
GORASP1	1903	3727
GOSR1	621	1215
GOSR2	1238	2441
KDELR1	-5094	10752
KDELR2	-5893	12387
KDELR3	976	1922
LMAN1	-3431	7220
LMAN2	-6558	13641
LMAN2L	-3429	7218
MAGT1	-7045	14398
MAN1A1	-1021	2084
MAN1A2	-6460	13466
MAN1B1	-3561	7534
MAN1C1	3072	5920
MAN2A1	-1040	2117
MAN2A2	-2336	4840
MANEA	4202	7987
MCFD2	-7065	14425
MGAT1	-6401	13371
MGAT2	-3327	7002
MGAT4A	-5018	10584
MGAT4B	-6279	13132
MGAT4C	1714	3364
MGAT5	-5854	12324
MIA3	-7049	14404
MLEC	-6902	14193
MOGS	-2275	4728
MPDU1	3718	7080
MPI	5076	9596
MVD	7302	14220
NAGK	4508	8559
NANP	483	957
NANS	-6906	14204
NAPA	-5921	12433
NAPB	-419	853
NAPG	-3872	8187
NEU1	-6752	13953
NEU3	7085	13653
NEU4	6950	13335
NGLY1	-2909	6049
NSF	-4839	10249
NUDT14	-4170	8814
NUS1	-6395	13362
OS9	-6986	14320
PDIA3	-7086	14454
PGM3	-5395	11367
PMM1	-2658	5521
PMM2	-5187	10956
PPP6C	-5241	11074
PPP6R1	-6511	13558
PPP6R3	-623	1271
PREB	1446	2868
PRKCSH	-5934	12463
PSMC1	-5564	11724
RAB1A	-3307	6957
RAB1B	-3479	7340
RAD23B	3141	6054
RENBP	-5761	12130
RFT1	5083	9608
RNF103	-6135	12848
RNF139	-3064	6382
RNF185	-6359	13291
RNF5	-6629	13745
RPN1	-7013	14350
RPN2	-6193	12964
RPS27A	-2773	5776
SAR1B	-2973	6198
SCFD1	485	960
SEC13	-6812	14049
SEC16A	-5971	12546
SEC16B	6744	12908
SEC22A	3312	6374
SEC22B	859	1690
SEC22C	-1684	3433
SEC23A	-2717	5659
SEC23IP	390	767
SEC24A	-6839	14088
SEC24B	-5475	11541
SEC24C	-6236	13047
SEC24D	-7134	14520
SEC31A	-5766	12138
SEL1L	-7124	14508
SERPINA1	4014	7622
SLC17A5	-7072	14434
SLC35A1	3906	7418
SLC35C1	-6667	13821
SPTAN1	2385	4610
SPTBN1	-4901	10356
SPTBN2	3883	7379
SRD5A3	4758	9027
ST3GAL1	-5905	12408
ST3GAL2	-4518	9594
ST3GAL3	5918	11257
ST3GAL4	-6801	14033
ST3GAL5	5090	9630
ST3GAL6	-3252	6829
ST6GAL1	-1828	3739
ST6GALNAC4	-6726	13912
ST6GALNAC6	-4820	10212
ST8SIA1	2289	4428
ST8SIA5	-1758	3583
STT3A	-6796	14026
STX17	2586	4997
STX5	-5300	11191
SYVN1	-7108	14485
TBC1D20	-6203	12985
TFG	-5336	11250
TGFA	-4511	9574
TMED10	-6116	12817
TMED2	-7071	14433
TMED3	-4057	8567
TMED7	-6933	14240
TMED9	-6502	13545
TMEM115	-6764	13976
TRAPPC1	3089	5956
TRAPPC10	-6585	13677
TRAPPC2	3547	6775
TRAPPC2L	-4576	9709
TRAPPC3	-4032	8524
TRAPPC4	1781	3487
TRAPPC5	239	470
TRAPPC6A	7244	14069
TRAPPC6B	2584	4993
TRAPPC9	5033	9528
TRIM13	1883	3695
TUSC3	-1219	2465
UAP1	-898	1828
UBA52	-5068	10707
UBB	-4263	9013
UBC	779	1551
UBXN1	-5450	11466
UGGT1	-6954	14270
UGGT2	1425	2839
USO1	-3509	7413
VCP	-6720	13902
YKT6	-4899	10349

---

---

Cellular responses to stress

Cellular responses to stress

metric	value
setSize	633
pMANOVA	6.23e-22
p.adjustMANOVA	2.86e-19
s.dist	0.235
s.x	-0.217
s.abs	0.0898
p.x	2.2e-20
p.abs	0.000129

Top 20 genes

Gene	x	abs
HSPA5	-7144	14531
CALR	-7142	14529
DNAJB11	-7141	14528
HYOU1	-7140	14527
HERPUD1	-7137	14524
DNAJC3	-7131	14516
HSP90B1	-7129	14514
DNAJB9	-7125	14510
SYVN1	-7108	14485
PDIA6	-7106	14482
EDEM1	-7103	14479
WFS1	-7096	14466
ATP6V0B	-7064	14422
GFPT1	-7051	14406
DDIT3	-7047	14401
EIF2AK3	-7028	14371
HM13	-7025	14368
FLCN	-7022	14362
RRAGC	-7009	14345
MAFK	-6985	14318

Click HERE to show all gene set members

All member genes

	x	abs
AAAS	2965	5701
ABCC1	-5950	12501
ACADVL	4157	7903
ACD	3041	5857
ACTR10	5570	10590
ACTR1A	-5162	10903
ADD1	-5966	12538
AGO1	4307	8173
AGO3	-5803	12205
AGO4	6581	12561
AJUBA	6013	11454
AKT1S1	-5990	12584
ALB	3096	5965
ANAPC1	1998	3900
ANAPC10	6071	11551
ANAPC11	-1544	3134
ANAPC15	-4945	10442
ANAPC16	6307	12018
ANAPC2	-1639	3349
ANAPC4	305	595
ANAPC5	3942	7485
ANAPC7	6249	11895
APOA1	6993	13433
APOB	-2964	6172
AQP8	-5439	11449
ARFGAP1	-1587	3224
ARNT	1014	1996
ARNTL	-359	732
ASF1A	3905	7415
ASNS	6208	11814
ATF2	-6175	12933
ATF3	2488	4803
ATF4	-5664	11932
ATF5	-6830	14076
ATF6	-6949	14261
ATM	1503	2965
ATOX1	3659	6974
ATP6V0B	-7064	14422
ATP6V0C	-6086	12764
ATP6V0D1	-6908	14206
ATP6V0D2	747	1494
ATP6V0E1	-6622	13731
ATP6V0E2	5683	10798
ATP6V1A	-3777	7965
ATP6V1B1	4549	8635
ATP6V1B2	-5574	11744
ATP6V1C1	-4946	10444
ATP6V1C2	-5929	12453
ATP6V1D	-6922	14228
ATP6V1E1	-6271	13114
ATP6V1E2	-534	1090
ATP6V1F	-868	1771
ATP6V1G1	-5352	11283
ATP6V1G2	690	1360
ATP6V1H	-4423	9358
ATP7A	2111	4123
ATR	5478	10396
BACH1	-4970	10478
BAG1	-4540	9631
BAG2	1269	2521
BAG3	-5335	11246
BAG4	4019	7633
BAG5	-5238	11071
BLVRA	-1440	2921
BLVRB	811	1602
BMI1	-4180	8838
BMT2	638	1250
CA9	-5494	11579
CABIN1	-2162	4476
CALR	-7142	14529
CAMK2A	4566	8669
CAMK2D	1711	3358
CAMK2G	2145	4176
CAPZA1	-4855	10272
CAPZA2	-1549	3143
CAPZB	-1169	2376
CARM1	3517	6725
CAT	5018	9504
CBX2	6958	13350
CBX4	-4063	8580
CBX6	2911	5608
CBX8	-4370	9242
CCAR2	-3268	6864
CCNA2	6594	12587
CCNE1	2754	5315
CCNE2	-2024	4152
CCS	4860	9214
CDC16	1175	2309
CDC23	6113	11639
CDC26	-197	402
CDC27	-1529	3103
CDK2	4114	7809
CDK4	-5064	10698
CDK6	4754	9023
CDKN1A	-3580	7569
CDKN1B	-786	1590
CDKN2A	3704	7056
CDKN2B	1710	3352
CDKN2C	4232	8034
CDKN2D	-4869	10296
CEBPB	-1129	2300
CEBPG	-5987	12578
CHAC1	6845	13119
CHD9	-4634	9842
CITED2	4227	8029
CLOCK	-1648	3360
COL4A6	5592	10629
COX11	1523	3007
COX14	-4004	8475
COX16	-910	1851
COX18	3788	7215
COX19	4126	7838
COX20	-6555	13633
COX4I1	-4038	8531
COX5A	-5033	10625
COX5B	704	1393
COX6A1	-3107	6487
COX6B1	-3158	6617
COX6C	344	661
COX7A2L	-4360	9228
COX7B	-3866	8175
COX7C	1483	2931
COX8A	-4517	9591
CREB1	474	935
CREB3	-3650	7725
CREB3L2	-6832	14080
CREB3L3	5999	11433
CREB3L4	5920	11259
CREBBP	-3888	8214
CREBRF	-4582	9731
CRTC1	2969	5705
CRTC2	-6651	13780
CRTC3	-4964	10469
CRYAB	939	1848
CSNK2A1	-5040	10637
CSNK2A2	-4546	9641
CSNK2B	4415	8368
CTDSP2	-4462	9444
CUL1	-4129	8725
CUL2	359	703
CUL3	-3056	6363
CUL7	4377	8310
CXCL8	3625	6916
CXXC1	-6033	12670
CYBA	2202	4283
CYCS	562	1098
DCP2	-5125	10825
DCTN1	-1635	3338
DCTN2	-3957	8375
DCTN3	1457	2887
DCTN4	-1937	3979
DCTN5	-3634	7690
DCTN6	-318	666
DDIT3	-7047	14401
DDX11	6254	11907
DEDD2	-3679	7779
DEPDC5	-4989	10518
DIS3	-1573	3190
DNAJA1	-2311	4793
DNAJA2	-3258	6843
DNAJB1	-6326	13228
DNAJB11	-7141	14528
DNAJB6	-5140	10856
DNAJB9	-7125	14510
DNAJC2	-4791	10157
DNAJC3	-7131	14516
DNAJC7	-6489	13527
DYNC1H1	-3614	7639
DYNC1I2	-2780	5783
DYNC1LI1	-2519	5237
DYNC1LI2	-3897	8235
DYNLL1	2509	4853
DYNLL2	6044	11507
E2F1	7096	13694
E2F2	6426	12251
E2F3	444	876
EDEM1	-7103	14479
EED	2369	4581
EEF1A1	-4138	8740
EGLN1	-4303	9096
EGLN2	-6763	13975
EGLN3	2588	5001
EHMT1	-1678	3422
EHMT2	400	784
EIF2AK1	-2921	6069
EIF2AK3	-7028	14371
EIF2AK4	-1455	2950
EIF2S1	-5190	10961
EIF2S2	-4458	9437
EIF2S3	-3669	7757
ELOB	-3004	6272
ELOC	645	1265
EP300	-6470	13485
EP400	-3754	7921
EPAS1	-4915	10387
EPO	2073	4044
ERF	-6016	12637
ERN1	-6872	14152
ERO1A	-198	403
ETS1	3554	6791
ETS2	-2186	4533
EXOSC1	3486	6667
EXOSC2	3779	7192
EXOSC3	-3453	7270
EXOSC4	3220	6193
EXOSC5	-4766	10117
EXOSC6	-6503	13547
EXOSC7	5196	9819
EXOSC8	472	928
EXOSC9	3293	6333
EXTL1	6941	13312
EXTL2	3353	6440
EXTL3	3575	6822
EZH2	-5631	11860
FABP1	5092	9636
FAU	-4990	10520
FBXL17	-4348	9200
FKBP14	-6896	14184
FKBP4	-5807	12213
FKBP5	5342	10097
FLCN	-7022	14362
FNIP1	-6782	13998
FNIP2	-5498	11587
FOS	-5174	10931
FZR1	201	397
GCN1	-4627	9826
GFPT1	-7051	14406
GOSR2	1238	2441
GPX1	3161	6089
GPX2	-6408	13379
GPX3	5394	10217
GPX7	2739	5287
GPX8	743	1486
GRB10	-5504	11598
GSK3A	-3684	7787
GSK3B	-5101	10767
GSR	-3534	7463
H2AFX	5356	10131
HBA1	-3024	6302
HDAC3	38	84
HDAC6	5953	11333
HDGF	-6715	13896
HELZ2	4786	9086
HERPUD1	-7137	14524
HIF1A	-4165	8807
HIF1AN	4302	8161
HIF3A	4444	8437
HIGD1A	720	1427
HIKESHI	6144	11695
HIRA	-6076	12746
HM13	-7025	14368
HMGA1	-5226	11043
HMGA2	5643	10714
HMOX1	4592	8715
HMOX2	-4742	10061
HSBP1	1372	2726
HSF1	-2414	5003
HSP90AA1	-1030	2096
HSP90AB1	-4426	9363
HSP90B1	-7129	14514
HSPA12A	5480	10402
HSPA13	-6786	14005
HSPA14	-5393	11362
HSPA1A	1835	3603
HSPA2	3418	6538
HSPA4	925	1816
HSPA4L	3936	7475
HSPA5	-7144	14531
HSPA6	-3353	7061
HSPA8	-4654	9895
HSPA9	-6580	13667
HSPB8	-5506	11600
HSPH1	-6524	13584
HYOU1	-7140	14527
ID1	4484	8511
IGFBP1	-3931	8301
IGFBP7	4272	8108
IMPACT	4432	8414
ITFG2	2143	4172
JUN	-2934	6103
KAT5	1580	3115
KDELR3	976	1922
KDM6B	-6944	14253
KEAP1	-6482	13510
KHSRP	-994	2029
KLHDC3	-3802	8036
KPTN	4478	8495
LAMTOR1	-774	1557
LAMTOR2	-148	299
LAMTOR3	-2631	5467
LAMTOR4	1834	3602
LAMTOR5	-5293	11181
LIMD1	2987	5738
LMNA	-3717	7854
LMNB1	7101	13707
LRPPRC	-5756	12122
LY96	-1339	2689
MAFK	-6985	14318
MAP2K3	-3342	7038
MAP2K4	-4505	9558
MAP2K6	-2351	4868
MAP2K7	-4399	9311
MAP4K4	-5792	12181
MAPK1	-5066	10705
MAPK10	2952	5681
MAPK11	251	492
MAPK14	2269	4391
MAPK3	6640	12684
MAPK7	-4382	9270
MAPK8	-700	1418
MAPK9	1760	3449
MAPKAPK2	-6461	13468
MAPKAPK3	-5773	12147
MAPKAPK5	-4050	8556
MBTPS1	-5958	12523
MBTPS2	3687	7019
MDM2	-956	1942
MDM4	-2561	5318
MED1	-5451	11468
MEF2D	-5995	12594
MINK1	2261	4372
MIOS	2912	5610
MLST8	1875	3677
MOV10	6408	12217
MRE11	4100	7780
MRPL18	-882	1806
MT-CO1	6493	12380
MT-CO2	716	1414
MT-CO3	7316	14274
MTOR	-3683	7785
MYDGF	-6976	14306
NBN	4533	8606
NCF2	-5438	11446
NCOA1	-4665	9914
NCOA2	4780	9072
NCOA6	-6745	13941
NCOR1	-4374	9256
NCOR2	-4409	9331
NDC1	-1490	3023
NDUFA4	-390	795
NFE2L2	-2108	4363
NFKB1	-3507	7409
NFYA	-2482	5142
NFYB	5091	9634
NFYC	-690	1395
NPAS2	-5410	11394
NPRL2	4876	9247
NPRL3	4164	7917
NR1D1	-4622	9818
NR3C1	-4005	8476
NR3C2	1520	2999
NRIP1	570	1114
NUDT2	301	589
NUP107	6076	11561
NUP133	1362	2708
NUP153	2712	5230
NUP155	4796	9102
NUP160	-329	683
NUP188	-4991	10521
NUP205	-5275	11144
NUP210	6802	13025
NUP214	-1926	3957
NUP35	5982	11387
NUP37	7100	13706
NUP43	2808	5410
NUP50	-4733	10047
NUP54	3310	6371
NUP58	2380	4603
NUP62	-299	618
NUP85	4178	7946
NUP88	-4777	10134
NUP93	5831	11067
NUP98	-3764	7940
P4HB	-6884	14170
PARN	-4578	9715
PDIA5	579	1130
PDIA6	-7106	14482
PHC1	-4280	9053
PHC2	3713	7072
PHC3	843	1660
PLA2G4B	4716	8953
POM121	-6353	13281
POM121C	-6045	12687
POT1	6132	11678
PPARA	-6722	13906
PPARGC1A	-5869	12350
PPP1R15A	-6783	13999
PPP2R5B	-5131	10834
PRDX1	-6673	13828
PRDX2	-961	1951
PRDX3	165	321
PRDX5	-1274	2560
PRDX6	-54	106
PREB	1446	2868
PRKCD	-5638	11872
PSMA1	-5730	12052
PSMA2	-5801	12203
PSMA3	-3078	6422
PSMA4	-4211	8902
PSMA5	-2715	5657
PSMA6	-126	261
PSMA7	-892	1820
PSMB1	1054	2062
PSMB10	423	838
PSMB2	1876	3678
PSMB3	-1915	3928
PSMB4	-1144	2330
PSMB5	-742	1484
PSMB6	-4888	10326
PSMB7	-4372	9253
PSMB9	5491	10430
PSMC1	-5564	11724
PSMC2	-2389	4948
PSMC3	-1509	3070
PSMC4	-4808	10196
PSMC5	-4091	8646
PSMC6	-4878	10307
PSMD1	-5351	11280
PSMD10	4933	9356
PSMD11	-432	879
PSMD12	4303	8163
PSMD13	-2577	5353
PSMD14	5974	11371
PSMD2	-6435	13423
PSMD3	-5535	11655
PSMD4	4567	8670
PSMD5	5116	9676
PSMD6	-5951	12502
PSMD7	4942	9371
PSMD8	-2928	6091
PSMD9	-4638	9853
PSME1	-2348	4861
PSME2	-5481	11555
PSME3	-3813	8052
PSME4	-6450	13450
PSMF1	-6663	13810
PTGES3	3734	7103
PTK6	3304	6358
RAD50	-4078	8623
RAE1	4394	8335
RAI1	-2008	4118
RANBP2	-4	9
RB1	470	925
RBBP4	-3297	6938
RBBP7	5134	9712
RBX1	-3714	7850
RELA	-2632	5468
RHEB	-3762	7936
RING1	4067	7710
RNF2	2454	4732
RORA	-5875	12360
RPA1	-5008	10563
RPA2	6961	13354
RPA3	6375	12149
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS19BP1	-6915	14217
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS6KA1	-3857	8159
RPS6KA2	-1149	2339
RPS6KA3	-3030	6316
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
RPTOR	407	803
RRAGA	2609	5038
RRAGB	-4819	10211
RRAGC	-7009	14345
RRAGD	-6743	13938
RXRA	-4073	8607
SCMH1	6656	12722
SCO1	-3018	6294
SCO2	-6638	13759
SEC13	-6812	14049
SEC31A	-5766	12138
SEH1L	-4472	9474
SEM1	-3130	6566
SERP1	-6964	14288
SERPINH1	-3945	8349
SESN1	4963	9414
SESN2	-6610	13712
SH3BP4	-3331	7014
SHC1	-6910	14209
SIN3A	-5884	12373
SIN3B	4029	7646
SIRT1	-5628	11855
SKP1	-544	1117
SKP2	5946	11323
SLC38A9	-5539	11664
SLC46A1	-835	1702
SMARCD3	2305	4455
SOD1	5779	10975
SOD2	7342	14367
SP1	-5412	11396
SRPRA	-4802	10175
SRPRB	-6893	14181
SSR1	-6907	14205
ST13	-4320	9142
STAP2	4664	8852
STAT3	4253	8078
STIP1	-3571	7550
SULT1A3	1040	2038
SURF1	327	631
SUZ12	346	664
SYVN1	-7108	14485
SZT2	5052	9557
TACO1	5527	10511
TATDN2	-6467	13480
TBL1X	-1621	3308
TBL1XR1	1404	2795
TCIRG1	180	348
TERF1	-5276	11145
TERF2	4479	8496
TERF2IP	-4282	9056
TFDP1	-2579	5361
TFDP2	4856	9210
TGS1	2148	4181
TINF2	4357	8275
TLN1	-6146	12872
TNFRSF21	-2173	4491
TNIK	4872	9243
TNRC6A	1824	3580
TNRC6B	-4212	8904
TNRC6C	-4805	10180
TP53	-2020	4144
TPP1	-6407	13378
TPR	565	1105
TRIB3	-6798	14029
TSPYL2	-6784	14002
TXN	-3611	7626
TXN2	-243	499
TXNIP	7384	14509
TXNRD1	-6806	14041
TXNRD2	308	603
UBA52	-5068	10707
UBB	-4263	9013
UBC	779	1551
UBE2C	7137	13793
UBE2D1	3523	6734
UBE2D2	-913	1857
UBE2D3	-3997	8449
UBE2E1	3733	7102
UBE2S	-1872	3839
UBN1	-5851	12306
VCP	-6720	13902
VEGFA	-4456	9433
VHL	-6491	13531
WDR24	4466	8468
WDR59	4915	9316
WFS1	-7096	14466
WIPI1	-6942	14251
WTIP	4170	7931
XBP1	5937	11302
XPO1	-1864	3824
YIF1A	195	381
YWHAE	129	253
ZBTB17	-3194	6703

---

---

Cholesterol biosynthesis

Cholesterol biosynthesis

metric	value
setSize	24
pMANOVA	2.36e-19
p.adjustMANOVA	8.13e-17
s.dist	1.07
s.x	0.843
s.abs	0.659
p.x	8.63e-13
p.abs	2.32e-08

Top 20 genes

Gene	x	abs
MSMO1	7385	14517
HMGCS1	7372	14473
SQLE	7370	14468
IDI1	7367	14452
HMGCR	7355	14408
MVK	7340	14363
DHCR7	7333	14319
MVD	7302	14220
FDFT1	7289	14189
LSS	7283	14165
ACAT2	6959	13351
ARV1	6888	13201
FDPS	6789	12999
CYP51A1	6741	12901
TM7SF2	6684	12785
NSDHL	6245	11890
DHCR24	5816	11041
GGPS1	5520	10498
SC5D	5323	10071
EBP	5151	9739

Click HERE to show all gene set members

All member genes

	x	abs
ACAT2	6959	13351
ARV1	6888	13201
CYP51A1	6741	12901
DHCR24	5816	11041
DHCR7	7333	14319
EBP	5151	9739
FDFT1	7289	14189
FDPS	6789	12999
GGPS1	5520	10498
HMGCR	7355	14408
HMGCS1	7372	14473
HSD17B7	2596	5017
IDI1	7367	14452
LBR	3485	6666
LSS	7283	14165
MSMO1	7385	14517
MVD	7302	14220
MVK	7340	14363
NSDHL	6245	11890
PLPP6	4705	8931
PMVK	3336	6407
SC5D	5323	10071
SQLE	7370	14468
TM7SF2	6684	12785

---

---

Infectious disease

Infectious disease

metric	value
setSize	637
pMANOVA	9.29e-18
p.adjustMANOVA	2.56e-15
s.dist	0.208
s.x	-0.206
s.abs	0.0247
p.x	1.06e-18
p.abs	0.292

Top 20 genes

Gene	x	abs
CALR	-7142	14529
DNAJC3	-7131	14516
CANX	-7092	14462
ANTXR2	-7077	14440
MAGT1	-7045	14398
MAP1LC3B	-7040	14388
RAMP1	-7037	14385
RPN1	-7013	14350
RPL36AL	-6981	14313
DVL3	-6967	14293
CTSL	-6951	14263
ATP1B3	-6941	14249
TGFB1	-6934	14241
MET	-6878	14159
SFPQ	-6854	14118
ACTG1	-6841	14090
SEC13	-6812	14049
TXNRD1	-6806	14041
ST3GAL4	-6801	14033
STT3A	-6796	14026

Click HERE to show all gene set members

All member genes

	x	abs
AAAS	2965	5701
ABI1	-4478	9492
ABI2	-1197	2431
ABL1	2023	3944
ACE2	2757	5319
ACTB	-5057	10683
ACTG1	-6841	14090
ACTR2	1435	2855
ACTR3	-5296	11186
ADAM17	-5836	12276
ADCY1	4808	9122
ADCY2	-667	1356
ADCY6	-2818	5862
ADCY7	6316	12040
ADCY9	4287	8130
ADM	-2543	5276
ADM2	-6068	12730
ADORA2A	5330	10081
ADORA2B	5127	9698
AHCYL1	4874	9245
ANTXR1	4532	8605
ANTXR2	-7077	14440
AP1B1	940	1849
AP1G1	-1916	3931
AP1M1	2926	5637
AP1M2	914	1788
AP1S1	5804	11022
AP1S2	-4204	8889
AP1S3	-739	1480
AP2A1	-1902	3903
AP2A2	-3499	7391
AP2B1	2029	3955
AP2M1	-4603	9787
AP2S1	-2922	6073
APOBEC3G	7066	13607
ARF1	-6021	12642
ARID4A	-156	323
ARID4B	480	945
ARPC1A	3022	5822
ARPC1B	-4429	9372
ARPC2	-2209	4575
ARPC3	3797	7237
ARPC4	-6094	12778
ARPC5	-1511	3073
ATP1A1	-6777	13992
ATP1A3	-1706	3489
ATP1A4	412	810
ATP1B1	-6624	13734
ATP1B2	-3692	7805
ATP1B3	-6941	14249
ATP6V1H	-4423	9358
B2M	-2523	5242
BAIAP2	-637	1295
BANF1	3790	7227
BECN1	-2900	6036
BRD4	-6479	13501
BRK1	-5431	11428
BRMS1	-6309	13195
BTRC	1386	2757
C3	7357	14417
CALM1	-655	1340
CALR	-7142	14529
CANX	-7092	14462
CASP1	6109	11631
CBL	-5708	12008
CBLL1	-5694	11979
CBX1	4668	8861
CCNH	5556	10565
CCNK	-1089	2223
CCNT1	-4690	9958
CCNT2	4117	7818
CD4	6074	11557
CD9	-3660	7746
CDC42	-2172	4489
CDH1	7296	14202
CDK7	-5444	11458
CDK9	2631	5091
CEBPD	6867	13165
CHD3	-1321	2661
CHD4	-4830	10236
CHMP1A	-5693	11973
CHMP2A	-1088	2222
CHMP2B	-878	1797
CHMP3	1229	2417
CHMP4A	909	1779
CHMP4B	-5021	10594
CHMP4C	-6557	13640
CHMP5	-1722	3519
CHMP6	5904	11222
CHMP7	2690	5197
CLTA	-6439	13432
CLTC	-6220	13017
COMT	2597	5019
CORO1A	3359	6451
CPSF4	1570	3094
CRBN	-1928	3959
CREB1	474	935
CRK	-5650	11901
CSNK1A1	-5349	11277
CTDP1	-4461	9443
CTNNB1	3272	6288
CTNND1	7129	13781
CTSL	-6951	14263
CUL3	-3056	6363
CUL5	-1229	2485
CYBA	2202	4283
CYFIP1	1939	3785
CYFIP2	6224	11850
CYSLTR1	2493	4813
DAD1	-6240	13053
DAXX	3635	6929
DBP	-2002	4112
DDOST	-6429	13410
DDX5	-6665	13814
DNAJC3	-7131	14516
DOCK1	3540	6760
DPEP1	-3163	6625
DRD5	4609	8753
DUSP16	-1750	3571
DUT	6636	12668
DVL1	-2264	4696
DVL2	-905	1843
DVL3	-6967	14293
DYNC1H1	-3614	7639
DYNC1I2	-2780	5783
DYNC1LI1	-2519	5237
DYNC1LI2	-3897	8235
DYNLL1	2509	4853
DYNLL2	6044	11507
EDEM2	-5520	11628
EED	2369	4581
EEF2	-5049	10659
EGFR	-5383	11344
EIF2AK2	2886	5562
ELK1	-5733	12060
ELL	-1439	2915
ELMO1	-2779	5782
ELMO2	942	1854
ELOA	-2831	5887
ELOB	-3004	6272
ELOC	645	1265
ENO1	-4866	10290
ENTPD1	184	358
ENTPD5	3958	7507
EPS15	1254	2479
ERCC2	-583	1192
ERCC3	-2013	4129
EZH2	-5631	11860
FAU	-4990	10520
FEN1	367	721
FKBP1A	-5189	10960
FKBP4	-5807	12213
FNTA	-6282	13142
FNTB	-2551	5296
FURIN	-6683	13851
FUT8	-5134	10839
FXYD1	-2847	5919
FXYD2	-5865	12339
FYN	1937	3783
FZD7	5487	10425
GALNT1	-816	1659
GANAB	2813	5417
GATAD2A	-4108	8682
GATAD2B	-1092	2228
GGT1	-250	514
GGT5	-4012	8488
GIPR	3556	6793
GNAI1	-2495	5167
GNAI2	-3904	8246
GNAI3	-4609	9793
GNAS	459	900
GNAZ	-3724	7864
GNB1	-3237	6796
GNB2	-4514	9583
GNB3	-1008	2063
GNB4	1936	3781
GNB5	700	1388
GNG10	6779	12977
GNG4	6164	11731
GNG5	4123	7830
GNG7	4426	8395
GPHA2	-3711	7837
GPR176	5289	10004
GPR39	994	1956
GPR83	1350	2691
GPS2	-4524	9607
GRB2	-3047	6346
GRSF1	-4747	10070
GSDMD	5413	10266
GSK3A	-3684	7787
GSK3B	-5101	10767
GTF2A1	328	633
GTF2A2	5445	10341
GTF2B	-5704	11995
GTF2E1	5502	10461
GTF2E2	-5813	12227
GTF2F1	-3103	6481
GTF2F2	4556	8650
GTF2H1	-5744	12095
GTF2H2	5321	10066
GTF2H3	6024	11478
GTF2H4	-406	824
GTF2H5	4373	8306
HBEGF	-4402	9320
HDAC1	-2676	5563
HDAC2	-338	693
HDAC3	38	84
HGS	-4210	8898
HLA-A	5777	10971
HMG20B	-3184	6676
HMGA1	-5226	11043
HMOX1	4592	8715
HNRNPK	-2808	5839
HSP90AA1	-1030	2096
HSP90AB1	-4426	9363
HSPA1A	1835	3603
HTR7	-5841	12283
IFNAR1	4161	7910
IFNAR2	-2313	4798
IFNGR1	1624	3204
IFNGR2	997	1962
IL18	2102	4103
IL1R1	6510	12430
IL6R	-4943	10440
IMPDH1	-1807	3690
IMPDH2	4910	9308
IPO5	-6366	13302
IRS1	3502	6691
ISG15	-5488	11568
ITGB1	-4145	8760
ITPR1	-4321	9146
ITPR2	2257	4366
ITPR3	-6088	12768
JAK1	-4963	10468
JAK2	-2719	5664
JAK3	7326	14295
JUN	-2934	6103
KDM1A	4224	8018
KEAP1	-6482	13510
KPNA1	-6701	13876
KPNA2	-4575	9708
KPNA3	-4357	9223
KPNA4	-1701	3478
KPNA5	258	506
KPNB1	-6379	13324
LCK	-6250	13069
LIG1	6206	11811
LIG4	6454	12304
LYN	-3038	6328
MAGT1	-7045	14398
MAN1B1	-3561	7534
MAN2A1	-1040	2117
MAP1LC3B	-7040	14388
MAP2K1	-4120	8704
MAP2K2	-6087	12766
MAP2K3	-3342	7038
MAP2K4	-4505	9558
MAP2K6	-2351	4868
MAP2K7	-4399	9311
MAPK1	-5066	10705
MAPK14	2269	4391
MAPK3	6640	12684
MAPK8	-700	1418
MBD3	-4543	9635
MC1R	7078	13634
MEFV	2468	4758
MET	-6878	14159
MGAT1	-6401	13371
MGAT2	-3327	7002
MGAT4A	-5018	10584
MGAT4B	-6279	13132
MGAT4C	1714	3364
MGAT5	-5854	12324
MNAT1	-205	420
MOGS	-2275	4728
MTA1	1810	3553
MTA2	-5619	11843
MTA3	6411	12223
MVB12A	5589	10620
MVB12B	-3629	7683
MYH9	-4726	10036
MYO10	-5290	11171
MYO1C	-1212	2457
MYO5A	-3500	7394
MYO9B	-5920	12432
NCBP1	-2151	4458
NCBP2	6823	13081
NCK1	1525	3010
NCKAP1	-2788	5794
NCKAP1L	-972	1980
NCKIPSD	5477	10395
NCOR1	-4374	9256
NCOR2	-4409	9331
NDC1	-1490	3023
NEDD4L	7233	14037
NELFA	-5284	11161
NELFB	-2298	4775
NELFCD	-3765	7941
NELFE	26	63
NFE2L2	-2108	4363
NFKB1	-3507	7409
NFKB2	-1311	2634
NMT1	-2085	4289
NMT2	1894	3710
NOXA1	5500	10451
NOXO1	10	21
NPM1	-2033	4183
NR3C1	-4005	8476
NT5E	-6296	13160
NUP107	6076	11561
NUP133	1362	2708
NUP153	2712	5230
NUP155	4796	9102
NUP160	-329	683
NUP188	-4991	10521
NUP205	-5275	11144
NUP210	6802	13025
NUP214	-1926	3957
NUP35	5982	11387
NUP37	7100	13706
NUP43	2808	5410
NUP50	-4733	10047
NUP54	3310	6371
NUP58	2380	4603
NUP62	-299	618
NUP85	4178	7946
NUP88	-4777	10134
NUP93	5831	11067
NUP98	-3764	7940
P2RX4	5401	10229
P2RY11	-6403	13374
PABPN1	-2037	4195
PACS1	414	814
PAK2	-4957	10458
PARP1	2974	5715
PARP10	5859	11125
PARP14	5386	10194
PARP16	-3842	8129
PARP4	462	908
PARP6	-1567	3181
PARP8	3263	6264
PARP9	6988	13424
PDCD6IP	-5380	11336
PGK1	-4810	10198
PHF21A	-1078	2202
PIK3C3	-5220	11026
PIK3R4	1132	2219
PLCG1	2511	4855
PLCG2	-3766	7942
PLK2	-5005	10551
PML	1051	2057
POLR2A	2705	5219
POLR2B	-3699	7815
POLR2C	-3425	7212
POLR2D	2418	4674
POLR2E	-4667	9916
POLR2F	-5283	11158
POLR2G	2003	3910
POLR2H	-3593	7590
POLR2I	4594	8717
POLR2J	-603	1234
POLR2K	5962	11350
POLR2L	-5471	11530
POM121	-6353	13281
POM121C	-6045	12687
PPIA	-4443	9393
PRKACA	1736	3407
PRKACB	-1429	2885
PRKAR1A	4	6
PRKAR1B	-1038	2113
PRKAR2A	-860	1753
PRKCSH	-5934	12463
PRKX	-553	1134
PRMT1	-4281	9055
PSIP1	7193	13933
PSMA1	-5730	12052
PSMA2	-5801	12203
PSMA3	-3078	6422
PSMA4	-4211	8902
PSMA5	-2715	5657
PSMA6	-126	261
PSMA7	-892	1820
PSMB1	1054	2062
PSMB10	423	838
PSMB2	1876	3678
PSMB3	-1915	3928
PSMB4	-1144	2330
PSMB5	-742	1484
PSMB6	-4888	10326
PSMB7	-4372	9253
PSMB9	5491	10430
PSMC1	-5564	11724
PSMC2	-2389	4948
PSMC3	-1509	3070
PSMC4	-4808	10196
PSMC5	-4091	8646
PSMC6	-4878	10307
PSMD1	-5351	11280
PSMD10	4933	9356
PSMD11	-432	879
PSMD12	4303	8163
PSMD13	-2577	5353
PSMD14	5974	11371
PSMD2	-6435	13423
PSMD3	-5535	11655
PSMD4	4567	8670
PSMD5	5116	9676
PSMD6	-5951	12502
PSMD7	4942	9371
PSMD8	-2928	6091
PSMD9	-4638	9853
PSME1	-2348	4861
PSME2	-5481	11555
PSME3	-3813	8052
PSME4	-6450	13450
PSMF1	-6663	13810
PSTPIP1	5948	11328
PTGES3	3734	7103
PTHLH	-6042	12681
PTK2	-4346	9198
PYCARD	6900	13221
RAB5A	-5408	11392
RAB7A	-5810	12220
RAC1	44	95
RAE1	4394	8335
RAMP1	-7037	14385
RAMP2	6288	11990
RAN	-6476	13497
RANBP1	1308	2605
RANBP2	-4	9
RANGAP1	3458	6615
RB1	470	925
RBBP4	-3297	6938
RBBP7	5134	9712
RBX1	-3714	7850
RCC1	-2159	4473
RCOR1	-3493	7376
RELA	-2632	5468
REST	-593	1214
RHBDF2	-3089	6446
RIPK1	-2886	6000
RNF213	5584	10611
RNGTT	-4400	9314
RNMT	4440	8428
ROCK1	-3594	7591
ROCK2	-2772	5775
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPN1	-7013	14350
RPN2	-6193	12964
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
SAP18	-3349	7051
SAP30	-5230	11054
SAP30L	-3887	8212
SEC13	-6812	14049
SEH1L	-4472	9474
SEM1	-3130	6566
SFPQ	-6854	14118
SH3GL1	-4200	8879
SH3KBP1	-917	1864
SIGMAR1	753	1508
SKP1	-544	1117
SLC25A4	-3203	6719
SLC25A5	-4001	8466
SLC25A6	-3733	7878
SNF8	-1198	2432
SRC	3962	7516
SRPK1	3007	5798
SRPK2	-1905	3907
SSRP1	-4525	9609
ST3GAL1	-5905	12408
ST3GAL2	-4518	9594
ST3GAL3	5918	11257
ST3GAL4	-6801	14033
ST6GAL1	-1828	3739
ST6GALNAC4	-6726	13912
STAM	5109	9665
STAM2	3080	5933
STAT2	76	146
STT3A	-6796	14026
STX1A	-2377	4922
STX1B	1841	3612
SUDS3	-2287	4748
SUGT1	1662	3265
SUMO1	3308	6365
SUPT16H	3202	6161
SUPT4H1	-2826	5881
SUPT5H	-5767	12140
SUZ12	346	664
SV2A	2966	5702
TAF1	788	1565
TAF10	626	1223
TAF11	-429	868
TAF12	6601	12600
TAF13	-5280	11153
TAF15	7061	13593
TAF2	-206	426
TAF3	-1222	2472
TAF4	-6108	12802
TAF4B	-4483	9500
TAF5	-2960	6167
TAF6	1145	2253
TAF7	-1012	2071
TAF9	-483	981
TAF9B	6106	11625
TBK1	-5169	10919
TBL1X	-1621	3308
TBL1XR1	1404	2795
TBP	3968	7524
TCEA1	-6409	13380
TGFB1	-6934	14241
TLR9	-2371	4913
TMPRSS2	1456	2886
TPR	565	1105
TRIM27	-4835	10241
TRIM28	-3099	6471
TSG101	-2130	4411
TUBB	5125	9694
TUSC3	-1219	2465
TXN	-3611	7626
TXNIP	7384	14509
TXNRD1	-6806	14041
TYK2	5066	9579
UBA52	-5068	10707
UBAP1	-1894	3882
UBB	-4263	9013
UBC	779	1551
UBE2I	-1318	2653
UVRAG	-6290	13151
VAMP1	3484	6665
VAMP2	-5088	10744
VAV2	2817	5425
VAV3	-4642	9861
VCP	-6720	13902
VEGFA	-4456	9433
VHL	-6491	13531
VPS25	2895	5587
VPS28	4152	7894
VPS33B	4043	7662
VPS36	2474	4767
VPS37A	-4187	8850
VPS37B	-4696	9967
VPS37C	-4620	9815
VPS37D	809	1599
VPS4A	2374	4592
VPS4B	-934	1894
VTA1	1653	3254
WASF1	-5712	12021
WASF2	-3366	7096
WASF3	2619	5070
WASL	-6543	13611
WIPF2	-2965	6174
XPO1	-1864	3824
XRCC4	3376	6479
XRCC5	-4164	8806
XRCC6	28	67
YES1	-1340	2690
ZCRB1	4731	8981

---

---

Signal Transduction

Signal Transduction

metric	value
setSize	1748
pMANOVA	2.01e-17
p.adjustMANOVA	4.62e-15
s.dist	0.131
s.x	-0.106
s.abs	0.0777
p.x	6.08e-13
p.abs	1.28e-07

Top 20 genes

Gene	x	abs
SEL1L	-7124	14508
ATP2A2	-7119	14500
MTMR4	-7109	14488
SYVN1	-7108	14485
TMED2	-7071	14433
ATP6V0B	-7064	14422
ARRB1	-7062	14420
PGF	-7053	14409
DERL2	-7046	14399
RAMP1	-7037	14385
SHB	-7035	14382
CX3CL1	-7031	14375
RUNX1	-7020	14359
SQSTM1	-7010	14347
RRAGC	-7009	14345
STEAP3	-6993	14327
GPER1	-6992	14326
OS9	-6986	14320
ATP6V0A1	-6979	14310
ARHGEF2	-6977	14307

Click HERE to show all gene set members

All member genes

	x	abs
AAAS	2965	5701
AAMP	-5076	10725
AATF	-5468	11526
ABCA1	-2289	4752
ABCD3	-405	821
ABCG5	6607	12609
ABCG8	2955	5687
ABHD12	-6295	13159
ABHD17A	-6185	12949
ABHD17B	-2101	4341
ABHD17C	6192	11785
ABHD6	957	1891
ABI1	-4478	9492
ABI2	-1197	2431
ABL1	2023	3944
ABL2	-3020	6296
ABR	-211	434
ACBD5	-4727	10037
ACKR2	5219	9863
ACTA2	7362	14438
ACTB	-5057	10683
ACTG1	-6841	14090
ACTN1	-6670	13824
ACTR2	1435	2855
ACTR3	-5296	11186
ACVR1B	4400	8345
ACVR2A	775	1545
ACVR2B	931	1830
ADAM10	-2671	5549
ADAM17	-5836	12276
ADAP1	-1403	2817
ADCY1	4808	9122
ADCY2	-667	1356
ADCY6	-2818	5862
ADCY7	6316	12040
ADCY9	4287	8130
ADD3	5685	10801
ADGRE2	1057	2068
ADGRE5	-313	651
ADH1A	6237	11878
ADH4	7331	14312
ADM	-2543	5276
ADM2	-6068	12730
ADORA2A	5330	10081
ADORA2B	5127	9698
ADRA1D	5547	10553
ADRA2C	-6434	13422
AGO1	4307	8173
AGO2	-5530	11647
AGO3	-5803	12205
AGO4	6581	12561
AGT	7091	13674
AGTR1	2260	4371
AHCTF1	-4070	8598
AHCYL1	4874	9245
AKAP12	-2868	5962
AKAP13	-6600	13699
AKR1C3	24	54
AKT1	-2958	6160
AKT1S1	-5990	12584
AKT2	-1946	3993
ALDH1A1	-4952	10453
ALDH1A2	-2454	5079
ALDH3A2	-4574	9706
ALDH8A1	2489	4804
ALS2	2318	4492
AMER1	5007	9484
AMOTL2	-6961	14282
ANKFY1	6079	11567
ANKLE2	-6513	13567
ANKRD26	7017	13489
ANLN	4979	9438
ANOS1	-3087	6441
AP2A1	-1902	3903
AP2A2	-3499	7391
AP2B1	2029	3955
AP2M1	-4603	9787
AP2S1	-2922	6073
APC	-1818	3716
APH1A	619	1209
APH1B	6168	11741
APOC1	746	1491
APOC2	5283	9992
APOE	-3670	7759
APP	-6492	13532
ARAF	-5242	11076
ARAP1	-1641	3351
ARAP2	-1642	3353
ARAP3	-4484	9501
ARC	-2587	5378
AREG	-4847	10258
ARF6	-5404	11385
ARFGAP2	1283	2547
ARFGAP3	-4817	10209
ARHGAP1	2833	5462
ARHGAP10	-233	474
ARHGAP11A	3756	7148
ARHGAP11B	6085	11580
ARHGAP12	-1400	2812
ARHGAP17	-3026	6310
ARHGAP18	-1308	2628
ARHGAP19	6733	12886
ARHGAP21	-4412	9336
ARHGAP22	1306	2602
ARHGAP23	-4953	10454
ARHGAP26	-2989	6232
ARHGAP27	4643	8813
ARHGAP28	-582	1191
ARHGAP29	4530	8603
ARHGAP32	-6905	14201
ARHGAP33	4686	8894
ARHGAP35	-6446	13445
ARHGAP39	-6303	13184
ARHGAP4	930	1829
ARHGAP40	-424	861
ARHGAP42	-5635	11866
ARHGAP44	6102	11618
ARHGAP5	-4477	9487
ARHGAP8	5008	9485
ARHGAP9	-2170	4486
ARHGDIA	-5377	11324
ARHGDIG	1275	2530
ARHGEF1	21	48
ARHGEF10L	5384	10192
ARHGEF11	-5260	11110
ARHGEF12	-1086	2216
ARHGEF16	-3936	8317
ARHGEF17	172	334
ARHGEF18	-909	1850
ARHGEF19	-2038	4198
ARHGEF2	-6977	14307
ARHGEF25	-3620	7665
ARHGEF26	4909	9307
ARHGEF28	-6925	14232
ARHGEF3	4045	7669
ARHGEF39	4647	8819
ARHGEF4	980	1931
ARHGEF40	6470	12329
ARHGEF5	-3818	8063
ARHGEF7	-2913	6055
ARHGEF9	5100	9653
ARL13B	5956	11337
ARL2	5716	10857
ARMCX3	-2911	6051
ARPC1A	3022	5822
ARPC1B	-4429	9372
ARPC2	-2209	4575
ARPC3	3797	7237
ARPC4	-6094	12778
ARPC5	-1511	3073
ARRB1	-7062	14420
ARRB2	-3248	6824
ARTN	973	1918
ASH2L	4729	8974
ATF1	-4925	10407
ATF2	-6175	12933
ATN1	-4249	8980
ATP2A1	4477	8492
ATP2A2	-7119	14500
ATP6AP1	-6235	13046
ATP6V0A1	-6979	14310
ATP6V0A2	-6880	14162
ATP6V0B	-7064	14422
ATP6V0C	-6086	12764
ATP6V0D1	-6908	14206
ATP6V0D2	747	1494
ATP6V0E1	-6622	13731
ATP6V0E2	5683	10798
ATP6V1A	-3777	7965
ATP6V1B1	4549	8635
ATP6V1B2	-5574	11744
ATP6V1C1	-4946	10444
ATP6V1C2	-5929	12453
ATP6V1D	-6922	14228
ATP6V1E1	-6271	13114
ATP6V1E2	-534	1090
ATP6V1F	-868	1771
ATP6V1G1	-5352	11283
ATP6V1G2	690	1360
ATP6V1H	-4423	9358
AURKB	6883	13190
AXIN1	-4215	8908
AXIN2	-5745	12097
AXL	-2605	5419
B4GALT1	-262	540
B9D2	-4569	9695
BAD	-6118	12822
BAG4	4019	7633
BAIAP2	-637	1295
BAIAP2L1	-6338	13253
BAIAP2L2	-3920	8278
BAMBI	6	13
BAX	4757	9026
BCAP31	-6129	12840
BCAR1	-6926	14233
BCL2	1925	3762
BCL2L1	-6349	13271
BCL2L11	-3834	8099
BCL9	-5924	12441
BCL9L	-6828	14074
BCR	-2502	5190
BEX3	7227	14021
BIRC2	-499	1007
BIRC3	3477	6654
BIRC5	5174	9771
BMI1	-4180	8838
BMPR1A	-166	345
BMPR2	2124	4145
BRAF	-4749	10077
BRAP	1211	2384
BRK1	-5431	11428
BTRC	1386	2757
BUB1	3416	6536
BUB1B	6992	13431
BUB3	1165	2290
C1QBP	-682	1380
C3	7357	14417
C5	7218	14003
C5AR1	6719	12862
C5AR2	3489	6671
CAB39	-4956	10457
CAB39L	734	1458
CALM1	-655	1340
CAMK2A	4566	8669
CAMK2D	1711	3358
CAMK2G	2145	4176
CAMK4	4196	7978
CAMKK1	-6422	13397
CAMKK2	3831	7294
CAPZB	-1169	2376
CARM1	3517	6725
CASP10	-5555	11704
CASP2	4204	7990
CASP3	-5257	11107
CASP8	3157	6085
CASP9	-5247	11084
CASR	2065	4021
CAV2	254	495
CBFB	-6381	13329
CBL	-5708	12008
CBX2	6958	13350
CBX4	-4063	8580
CBX6	2911	5608
CBX8	-4370	9242
CBY1	5965	11354
CCDC115	548	1075
CCDC88A	5267	9957
CCDC88C	-2163	4477
CCL16	4092	7766
CCL20	-6885	14171
CCL22	584	1142
CCL28	-252	520
CCNC	-2471	5121
CCND1	-137	277
CCND3	-2677	5565
CCNE1	2754	5315
CCNK	-1089	2223
CCNT1	-4690	9958
CCNT2	4117	7818
CCP110	6203	11807
CCR10	1905	3730
CCR4	1897	3715
CCR6	-6932	14239
CCT2	-5926	12444
CCT6A	-5862	12336
CCT7	-1465	2974
CD19	-472	954
CD55	-6517	13575
CDC14A	127	249
CDC14B	3537	6755
CDC20	5650	10732
CDC25C	6825	13084
CDC37	-5178	10941
CDC42	-2172	4489
CDC42BPA	-5937	12468
CDC42BPB	-5357	11293
CDC42EP1	-1064	2171
CDC42EP2	-5487	11566
CDC42EP4	-6344	13265
CDC42SE2	5380	10187
CDC73	-4683	9943
CDCA8	6649	12700
CDH1	7296	14202
CDK1	7230	14027
CDK2	4114	7809
CDK4	-5064	10698
CDK5	-1352	2721
CDK5R1	-157	326
CDK8	-4276	9040
CDK9	2631	5091
CDKN1A	-3580	7569
CDKN1B	-786	1590
CDKN2B	1710	3352
CDON	2669	5163
CENPA	4546	8625
CENPC	5660	10756
CENPE	5538	10538
CENPF	4197	7980
CENPH	6241	11884
CENPI	5963	11351
CENPK	7030	13518
CENPL	748	1495
CENPM	5262	9951
CENPN	2264	4377
CENPO	-404	820
CENPP	1371	2725
CENPQ	5907	11227
CENPT	4715	8952
CENPU	4358	8282
CEP97	5393	10215
CETP	2836	5470
CFL1	-5737	12075
CFLAR	-2258	4684
CGN	1314	2619
CHD1	-3315	6976
CHD3	-1321	2661
CHD4	-4830	10236
CHD8	-4588	9744
CHEK1	4365	8292
CHN1	-1698	3467
CHN2	-5305	11204
CHUK	-3364	7086
CIT	6027	11482
CKAP4	-3939	8327
CKAP5	6626	12651
CKB	-3007	6276
CLASP1	1561	3071
CLASP2	-4246	8977
CLIP1	-5947	12494
CLIP3	5347	10109
CLTA	-6439	13432
CLTB	-6064	12719
CLTC	-6220	13017
CNKSR1	3649	6956
CNOT6L	5623	10678
CNR2	-204	418
COL4A5	6694	12804
COL6A1	7322	14284
COL6A2	3222	6195
COL6A3	2085	4068
COL9A2	7348	14389
COL9A3	7151	13817
COPS2	-5161	10902
COPS4	-28	51
CPD	6859	13139
CPNE8	-3609	7624
CPSF7	-2243	4652
CPT1A	7075	13626
CPT1B	3852	7323
CRABP2	-4007	8479
CREB1	474	935
CREBBP	-3888	8214
CRK	-5650	11901
CRKL	524	1039
CSF2RA	43	94
CSK	-4113	8692
CSNK1A1	-5349	11277
CSNK1E	3247	6238
CSNK1G2	-1143	2329
CSNK2A1	-5040	10637
CSNK2A2	-4546	9641
CSNK2B	4415	8368
CTBP1	-41	73
CTBP2	-4982	10508
CTNNA1	-5558	11711
CTNNB1	3272	6288
CTNNBIP1	3826	7284
CTNND1	7129	13781
CTSD	2812	5416
CTTN	982	1934
CUL1	-4129	8725
CUL3	-3056	6363
CUL5	-1229	2485
CX3CL1	-7031	14375
CXCL16	-5783	12165
CXCL8	3625	6916
CXCR2	1464	2899
CXXC5	-5859	12331
CYBA	2202	4283
CYFIP1	1939	3785
CYFIP2	6224	11850
CYLD	-6066	12727
CYP26B1	-4218	8914
CYSLTR1	2493	4813
DAAM1	-4459	9439
DAB2IP	-6128	12838
DAGLA	-6851	14113
DAGLB	-4017	8497
DBN1	-5099	10764
DBT	3444	6586
DDRGK1	-5991	12585
DDX39B	-1996	4095
DDX5	-6665	13814
DEF6	4058	7696
DEPDC1B	6112	11636
DERL2	-7046	14399
DGKA	5708	10844
DGKD	-2554	5302
DGKE	-5985	12576
DGKG	1694	3322
DGKH	802	1586
DGKK	5277	9983
DGKQ	-1982	4067
DGKZ	-6208	12992
DHRS3	3195	6151
DHRS4	6459	12312
DIAPH1	-5806	12211
DIAPH2	2492	4808
DIAPH3	5020	9508
DISP2	1498	2959
DKK1	4410	8362
DKK4	-5490	11570
DLAT	-1575	3193
DLC1	-6599	13698
DLD	4167	7922
DLG1	-3865	8171
DLG2	-2019	4143
DLG3	5168	9763
DLG4	5108	9664
DLG5	-5644	11889
DLGAP5	5662	10758
DLK1	3351	6437
DNAJB1	-6326	13228
DNAL4	6609	12616
DNM1	6505	12417
DNM2	-6535	13597
DNMBP	-1516	3080
DOCK1	3540	6760
DOCK4	-1171	2380
DOCK5	4491	8523
DOCK6	-639	1298
DOCK7	3822	7277
DOCK8	-1981	4066
DOCK9	1751	3436
DOK1	4072	7718
DRAP1	2970	5707
DRD5	4609	8753
DSG2	-4228	8936
DSN1	6916	13258
DSP	-4746	10069
DST	-1950	4001
DTX2	-3377	7114
DTX4	3048	5869
DUSP1	-5567	11733
DUSP10	-5271	11134
DUSP16	-1750	3571
DUSP3	-6541	13608
DUSP4	-5977	12556
DUSP5	-5568	11735
DUSP6	-3376	7113
DUSP7	-3870	8185
DUSP8	4879	9251
DUSP9	-284	580
DVL1	-2264	4696
DVL2	-905	1843
DVL3	-6967	14293
DYNC1H1	-3614	7639
DYNC1I2	-2780	5783
DYNC1LI1	-2519	5237
DYNC1LI2	-3897	8235
DYNC2H1	-5775	12153
DYNLL1	2509	4853
DYNLL2	6044	11507
DZIP1	5496	10439
E2F1	7096	13694
E2F3	444	876
E2F4	-3153	6609
E2F5	1069	2102
EBAG9	1586	3126
ECE1	-5583	11768
ECE2	-4044	8542
ECT2	-4944	10441
EDN1	6766	12955
EED	2369	4581
EEF2K	6964	13359
EEPD1	-4610	9795
EFCAB7	6202	11806
EFHD2	3725	7090
EGFR	-5383	11344
EGR1	-1475	2989
EGR2	-3207	6724
EGR3	-3972	8399
EIF4B	-5898	12396
EIF4E	2473	4766
EIF4EBP1	4858	9212
EIF4G1	-5901	12400
ELF3	4575	8687
ELK1	-5733	12060
ELMO1	-2779	5782
ELMO2	942	1854
EMC3	-6661	13805
EMD	-3504	7404
EP300	-6470	13485
EPAS1	-4915	10387
EPHA2	-6857	14124
EPN1	-737	1478
EPO	2073	4044
EPOR	3992	7581
EPS15	1254	2479
EPS15L1	3478	6655
ERBB2	5534	10533
ERBB3	4249	8072
ERBIN	-2316	4809
ERCC6L	39	86
EREG	3467	6635
ERLEC1	-6168	12918
ESR2	3316	6378
ESRP2	-2361	4883
ESYT1	-6539	13601
ETV4	-4971	10479
EVC	5630	10692
EVL	2467	4757
EZH2	-5631	11860
F11R	7054	13568
F2	635	1246
F2R	3850	7320
F2RL1	-6927	14234
F2RL3	2685	5187
F3	1642	3237
FABP5	4021	7635
FADD	1889	3704
FAF2	-4640	9859
FAM135A	-4927	10410
FAM13A	2086	4071
FAM13B	-5513	11613
FAM169A	2362	4565
FAM91A1	-3805	8041
FARP1	5879	11169
FARP2	3688	7020
FAS	2303	4451
FASN	1885	3698
FBXW7	-2564	5325
FER	4431	8408
FERMT2	-3698	7814
FES	5506	10476
FGA	7336	14346
FGB	7226	14018
FGD1	2720	5245
FGD2	-487	990
FGD3	7036	13525
FGD4	6382	12166
FGF17	-4015	8493
FGF23	2097	4091
FGF5	342	659
FGFBP3	6730	12881
FGFR1	-6191	12960
FGFR2	6811	13048
FGFR3	-1195	2426
FGFR4	-2795	5810
FGFRL1	-3751	7915
FGG	6697	12809
FKBP1A	-5189	10960
FKBP4	-5807	12213
FKBP5	5342	10097
FLNA	-6833	14081
FLOT1	1317	2624
FLOT2	7147	13811
FLRT1	3504	6694
FLRT2	3988	7566
FLRT3	7184	13907
FLT3LG	6000	11436
FLT4	2167	4214
FMNL1	-2403	4980
FMNL2	-4100	8666
FMNL3	1155	2271
FN1	-3115	6525
FNBP1	-6371	13314
FNBP1L	1226	2414
FNTA	-6282	13142
FNTB	-2551	5296
FOS	-5174	10931
FOSB	-6091	12773
FOSL1	-6672	13826
FOXA1	5915	11252
FOXO1	5418	10275
FOXO3	2282	4415
FOXO4	-2077	4276
FRAT1	5212	9849
FRAT2	-4922	10404
FRK	602	1179
FRS2	-3790	8007
FRS3	2112	4125
FST	-2393	4958
FSTL3	-5252	11092
FURIN	-6683	13851
FYN	1937	3783
FZD1	4591	8714
FZD3	1245	2458
FZD4	6534	12474
FZD5	4841	9179
FZD6	6312	12029
FZD7	5487	10425
FZD8	2263	4376
FZD9	-6213	13007
GAB1	1575	3105
GAB2	-4127	8722
GABRB3	1163	2287
GABRG2	2849	5492
GABRG3	-451	919
GALNT3	-3227	6774
GALR1	2816	5422
GALR2	-3664	7752
GAS8	1964	3836
GATAD2A	-4108	8682
GATAD2B	-1092	2228
GDNF	-3969	8396
GFAP	2552	4934
GFOD1	-3825	8080
GFRA3	4393	8334
GGA3	4199	7982
GIPR	3556	6793
GIT1	-5582	11767
GIT2	4402	8347
GMIP	5817	11044
GNA11	-5916	12425
GNA12	-6278	13131
GNA13	-6594	13689
GNAI1	-2495	5167
GNAI2	-3904	8246
GNAI3	-4609	9793
GNAL	4390	8331
GNAQ	803	1588
GNAS	459	900
GNAZ	-3724	7864
GNB1	-3237	6796
GNB2	-4514	9583
GNB3	-1008	2063
GNB4	1936	3781
GNB5	700	1388
GNG10	6779	12977
GNG4	6164	11731
GNG5	4123	7830
GNG7	4426	8395
GNRH1	-3111	6508
GNRHR2	3579	6834
GOLGA3	-6836	14085
GOLGA7	-3421	7208
GOLGA8R	4017	7631
GOPC	1629	3212
GPAM	6968	13366
GPER1	-6992	14326
GPHA2	-3711	7837
GPNMB	4151	7893
GPR143	-2627	5460
GPR161	1180	2317
GPR176	5289	10004
GPR35	-2701	5616
GPR39	994	1956
GPR83	1350	2691
GPS1	-3506	7406
GPS2	-4524	9607
GPSM1	559	1094
GPSM2	3970	7530
GPSM3	-2116	4383
GRAP	-3478	7339
GRB10	-5504	11598
GRB2	-3047	6346
GRB7	-4006	8477
GREB1	6757	12928
GRIN1	-442	902
GRIN2B	1330	2648
GRIN2D	-5370	11311
GRK2	1205	2372
GRK3	-3418	7203
GRK5	-6	12
GRK6	1151	2263
GSK3A	-3684	7787
GSK3B	-5101	10767
GTF2A1	328	633
GTF2A2	5445	10341
GTF2F1	-3103	6481
GTF2F2	4556	8650
H2AFX	5356	10131
HBEGF	-4402	9320
HCAR1	2353	4549
HCAR2	2882	5556
HCAR3	3253	6248
HDAC1	-2676	5563
HDAC10	-1408	2826
HDAC11	1004	1970
HDAC2	-338	693
HDAC3	38	84
HDAC4	-1478	2998
HDAC5	-4034	8527
HDAC6	5953	11333
HDAC7	130	254
HDAC8	3835	7301
HEBP1	-6361	13295
HECW1	-1713	3499
HES1	7265	14121
HEY1	-3864	8169
HGFAC	6708	12835
HGS	-4210	8898
HHAT	4068	7712
HIF1A	-4165	8807
HINT2	6227	11856
HMOX2	-4742	10061
HNRNPA1	-1795	3661
HNRNPC	1814	3563
HNRNPF	-6735	13925
HNRNPH1	3111	5994
HNRNPM	-6829	14075
HPN	6820	13075
HRAS	-5543	11673
HSP90AA1	-1030	2096
HSP90AB1	-4426	9363
HSPB1	-3343	7039
HSPE1	844	1662
HTR1D	1778	3482
HTR7	-5841	12283
ICMT	2988	5741
ID1	4484	8511
ID2	-282	576
ID3	2220	4312
IFT122	2370	4583
IFT140	4429	8404
IFT172	3605	6880
IFT52	2860	5515
IFT57	-852	1736
IFT88	5432	10317
IGF1R	-2746	5730
IGF2	7375	14477
IGF2BP1	-4754	10096
IHH	-4252	8989
IKBKB	-2931	6100
IKBKG	-5946	12493
IL17RD	4497	8541
IL1RAP	5361	10146
IL1RL1	347	665
IL32	5419	10276
IL6R	-4943	10440
IL6ST	1965	3837
INCENP	5290	10005
INHBB	-2320	4815
INSR	-5097	10761
INTU	5699	10822
IQCE	-4208	8895
IQGAP1	-5663	11931
IQGAP2	-5323	11231
IQGAP3	6928	13282
IRAK1	-2218	4593
IRAK4	1591	3137
IRS1	3502	6691
IRS2	-5461	11497
ITCH	-6089	12771
ITGA2	-6205	12988
ITGA2B	-688	1391
ITGA3	-1662	3390
ITGAV	-4312	9120
ITGB1	-4145	8760
ITGB3BP	6398	12199
ITPR1	-4321	9146
ITPR2	2257	4366
ITPR3	-6088	12768
ITSN1	159	311
ITSN2	-546	1120
JAG1	-6948	14259
JAG2	-516	1048
JAK1	-4963	10468
JAK2	-2719	5664
JAK3	7326	14295
JUN	-2934	6103
JUNB	-3526	7447
JUND	4563	8660
JUP	2314	4478
KALRN	-408	828
KANK1	4837	9175
KAT2A	5077	9597
KAT2B	-4792	10158
KAT5	1580	3115
KBTBD7	6772	12967
KCTD13	-3029	6315
KCTD3	4624	8775
KCTD6	-178	368
KDM1A	4224	8018
KDM1B	-4647	9876
KDM3A	-6378	13323
KDM4A	-6254	13073
KDM4B	-59	117
KDM4C	-5149	10878
KHDRBS1	1341	2669
KHDRBS3	-3395	7153
KIDINS220	-6056	12710
KIF14	5224	9870
KIF18A	5234	9884
KIF2A	-5815	12231
KIF2C	5981	11386
KIF3A	3299	6347
KIF5A	-6634	13752
KIF5B	-5426	11419
KIF7	6216	11828
KISS1	-2999	6261
KISS1R	2780	5359
KITLG	92	180
KLB	-3807	8045
KLC1	4611	8755
KLC2	-3375	7112
KLC3	3105	5986
KLC4	3897	7401
KLHL12	6844	13118
KMT2D	-6260	13087
KNG1	7382	14503
KNL1	7073	13621
KNTC1	6674	12758
KPNA2	-4575	9708
KRAS	-2044	4210
KREMEN1	364	715
KREMEN2	-791	1609
KSR1	-1	5
KTN1	-3223	6769
LAMA1	1285	2553
LAMA3	-5316	11218
LAMA4	790	1568
LAMA5	6638	12680
LAMB1	3783	7198
LAMB2	495	978
LAMB3	-673	1365
LAMC1	-1300	2611
LAMC2	-228	466
LAMC3	1169	2298
LAMTOR1	-774	1557
LAMTOR2	-148	299
LAMTOR3	-2631	5467
LAMTOR4	1834	3602
LAMTOR5	-5293	11181
LAT	-3697	7813
LATS1	-3238	6798
LATS2	-6101	12786
LBR	3485	6666
LCK	-6250	13069
LEMD3	-919	1868
LEO1	-3088	6444
LEPR	-88	183
LETM1	-5941	12482
LFNG	-1376	2769
LGR4	-395	802
LGR5	-1600	3252
LIMK1	1565	3082
LIMK2	6394	12193
LIN7B	3131	6030
LMAN1	-3431	7220
LMNB1	7101	13707
LPAR2	2695	5209
LPAR6	6924	13275
LRIG1	-6280	13140
LRP5	-2319	4812
LRP6	-4613	9800
LRRC1	1170	2299
LRRC41	1992	3889
LTB4R	-754	1507
LTB4R2	1059	2072
LYL1	726	1438
LYN	-3038	6328
LYPLA1	3378	6485
MAD1L1	4350	8264
MAD2L1	7070	13616
MADD	-5505	11599
MAF1	-5705	11999
MAGED1	5797	11010
MAML1	-6891	14179
MAML2	6847	13122
MAP2K1	-4120	8704
MAP2K2	-6087	12766
MAP2K5	-2441	5053
MAP3K11	-4272	9031
MAP3K7	3767	7172
MAPK1	-5066	10705
MAPK11	251	492
MAPK12	-5538	11663
MAPK13	-1875	3846
MAPK14	2269	4391
MAPK3	6640	12684
MAPK6	-6249	13068
MAPK7	-4382	9270
MAPK8	-700	1418
MAPKAP1	-5936	12466
MAPKAPK2	-6461	13468
MAPKAPK3	-5773	12147
MAPKAPK5	-4050	8556
MAPRE1	-3795	8020
MARK3	-3996	8448
MATK	851	1673
MBD3	-4543	9635
MC1R	7078	13634
MCAM	-4158	8792
MCF2L	531	1047
MCHR1	-4371	9250
MDK	4615	8761
MDM2	-956	1942
MED1	-5451	11468
MEF2A	-3308	6959
MEF2D	-5995	12594
MEMO1	-5843	12288
MEN1	1298	2581
MET	-6878	14159
MFN1	-3811	8050
MFN2	-5992	12586
MFNG	6743	12905
MIB1	1650	3250
MIB2	-4356	9222
MIS12	-6367	13304
MKNK1	-2340	4846
MKRN1	-5695	11981
MKS1	6422	12242
MLST8	1875	3677
MMP2	-4677	9932
MMP3	-1680	3425
MOB1A	340	656
MOB1B	3012	5806
MOSPD2	1344	2673
MOV10	6408	12217
MPP7	2491	4807
MRAS	5118	9679
MSI2	-2422	5020
MST1	-4720	10022
MST1R	5156	9745
MTA1	1810	3553
MTA2	-5619	11843
MTA3	6411	12223
MTMR1	739	1468
MTMR4	-7109	14488
MTOR	-3683	7785
MTR	6057	11525
MTX1	-2595	5395
MUC13	-1524	3097
MUC20	-1019	2082
MXD4	-5116	10802
MYC	1892	3708
MYD88	5939	11305
MYH10	2558	4942
MYH11	1015	1998
MYH14	5492	10431
MYH9	-4726	10036
MYL12B	-6653	13785
MYL6	-6380	13325
MYL9	2704	5218
MYLIP	-6047	12695
MYLK	3757	7150
MYO19	-941	1909
MYO6	2665	5156
MYO9A	-1107	2252
MYO9B	-5920	12432
NAB1	765	1529
NAB2	-6372	13315
NBEA	2723	5256
NCBP1	-2151	4458
NCBP2	6823	13081
NCF2	-5438	11446
NCK1	1525	3010
NCK2	-3916	8271
NCKAP1	-2788	5794
NCKAP1L	-972	1980
NCKIPSD	5477	10395
NCOA1	-4665	9914
NCOA2	4780	9072
NCOA3	-2326	4825
NCOR1	-4374	9256
NCOR2	-4409	9331
NCSTN	-554	1137
NDC80	7161	13840
NDE1	-1744	3555
NDEL1	-5652	11904
NDUFA5	4165	7919
NDUFS3	-551	1132
NEDD4	196	383
NEDD4L	7233	14037
NEDD8	580	1131
NELFB	-2298	4775
NET1	-5731	12058
NEURL1B	3778	7190
NF1	1648	3245
NF2	-6559	13642
NFKB1	-3507	7409
NFKBIA	-6437	13427
NGEF	7064	13605
NGFR	-847	1726
NISCH	5985	11403
NLK	-733	1473
NLN	3407	6521
NMB	-251	517
NOS3	-4903	10359
NOTCH1	-3923	8281
NOTCH2	6231	11869
NOTCH3	4292	8138
NOTUM	6788	12998
NOX3	-4056	8566
NOXA1	5500	10451
NOXO1	10	21
NPB	-1537	3121
NPFFR1	4289	8135
NPHP4	-1636	3341
NPW	-2970	6185
NR1H2	193	373
NR1H3	4678	8878
NR3C1	-4005	8476
NR4A1	3691	7026
NR5A2	-5547	11680
NRAS	2310	4465
NRIP1	570	1114
NRP1	1353	2695
NRP2	-5313	11212
NRTN	3870	7357
NSFL1C	1848	3630
NSL1	3516	6722
NSMAF	451	884
NTSR1	-1675	3412
NUDC	-6662	13808
NUF2	7008	13470
NUMB	-5224	11036
NUP107	6076	11561
NUP133	1362	2708
NUP160	-329	683
NUP37	7100	13706
NUP43	2808	5410
NUP85	4178	7946
NUP98	-3764	7940
OBSCN	3598	6868
OCRL	6835	13103
OFD1	-45	83
OPHN1	6348	12089
OPN3	6679	12767
OPRD1	1233	2430
OPRL1	6531	12469
OS9	-6986	14320
OSBPL11	-2229	4618
OTUD3	-2342	4849
OTUD7B	-1911	3920
OTULIN	-2499	5175
OXER1	5459	10369
OXTR	-2112	4374
P2RY11	-6403	13374
P2RY2	-4163	8802
P4HB	-6884	14170
PAFAH1B1	-118	237
PAG1	2774	5350
PAK1	1031	2021
PAK2	-4957	10458
PAK4	-5359	11295
PAQR3	3763	7167
PARD3	-6165	12914
PARD6A	5924	11269
PARD6B	-3675	7771
PARP1	2974	5715
PBX1	827	1631
PCK1	6525	12455
PCP2	4061	7703
PCSK5	3449	6597
PCSK6	5326	10075
PDE11A	4728	8972
PDE3A	-5805	12209
PDE3B	-5303	11196
PDE4A	-3039	6332
PDE4C	2441	4711
PDE4D	-6396	13364
PDE6A	-172	354
PDE6D	6611	12619
PDE6G	70	134
PDE7A	-1290	2591
PDE8A	-4877	10306
PDGFA	-2660	5524
PDGFB	6920	13263
PDGFC	-5072	10716
PDGFRB	-6820	14062
PDHA1	-1224	2478
PDHB	1808	3550
PDHX	-4992	10522
PDK1	2405	4644
PDK2	6826	13086
PDK3	-2228	4617
PDK4	4595	8724
PDPK1	399	782
PEA15	3314	6376
PEAK1	-4528	9614
PEBP1	-6972	14300
PELP1	-2894	6020
PFN1	-6285	13146
PFN2	6877	13179
PGF	-7053	14409
PGRMC2	-3863	8168
PHB	-4920	10399
PHC1	-4280	9053
PHC2	3713	7072
PHC3	843	1660
PHIP	2538	4905
PHLPP1	-5029	10618
PHLPP2	-3934	8313
PICALM	2021	3941
PIK3AP1	-6957	14273
PIK3C3	-5220	11026
PIK3CA	-2813	5849
PIK3CB	-2588	5379
PIK3CD	-4759	10102
PIK3R1	-4376	9259
PIK3R2	-1355	2728
PIK3R3	-2279	4734
PIK3R4	1132	2219
PIN1	3074	5922
PIP4K2A	-5495	11582
PIP4K2B	2639	5102
PIP4K2C	-6335	13241
PIP5K1A	-1831	3743
PIP5K1B	1047	2051
PIP5K1C	-3229	6778
PKN1	-4731	10044
PKN2	620	1213
PKN3	3362	6455
PKP4	-1800	3674
PLAT	4797	9105
PLCB1	-6196	12974
PLCB3	-2412	4999
PLCG1	2511	4855
PLCG2	-3766	7942
PLD1	7290	14191
PLD2	4048	7673
PLEKHG1	966	1905
PLEKHG2	-5061	10691
PLEKHG3	484	958
PLEKHG4	3233	6215
PLEKHG5	-630	1283
PLEKHG6	-1364	2747
PLG	7380	14495
PLIN1	3775	7186
PLIN3	-5406	11389
PLK1	5045	9548
PLPPR1	4765	9043
PLPPR2	-29	52
PLTP	-4883	10314
PLXNA1	-1050	2146
PLXNB1	-1046	2132
PLXND1	-5686	11963
PMF1	-2433	5043
PML	1051	2057
POFUT1	4155	7899
POGLUT1	-6385	13337
POLR2A	2705	5219
POLR2B	-3699	7815
POLR2C	-3425	7212
POLR2D	2418	4674
POLR2E	-4667	9916
POLR2F	-5283	11158
POLR2G	2003	3910
POLR2H	-3593	7590
POLR2I	4594	8717
POLR2J	-603	1234
POLR2K	5962	11350
POLR2L	-5471	11530
PORCN	320	622
POTEE	4752	9019
POU2F1	1266	2513
PPARD	-788	1594
PPARG	-3168	6636
PPID	-4119	8703
PPM1A	-5736	12067
PPP1CA	-5153	10883
PPP1CB	-3630	7685
PPP1CC	-3392	7149
PPP1R12A	1114	2182
PPP1R12B	-4126	8721
PPP1R15A	-6783	13999
PPP2CA	-5168	10917
PPP2CB	-4523	9606
PPP2R1A	-4744	10064
PPP2R1B	4614	8759
PPP2R5A	-5740	12088
PPP2R5B	-5131	10834
PPP2R5C	2743	5293
PPP2R5D	-2117	4385
PPP2R5E	283	554
PPP3CA	381	748
PPP3CB	-4060	8574
PPP3CC	-2712	5641
PPP3R1	-4176	8832
PPP5C	2684	5186
PRC1	6550	12500
PRDM4	-6194	12965
PRKAA1	5206	9840
PRKAA2	-3053	6357
PRKAB1	-680	1376
PRKAB2	-1763	3594
PRKACA	1736	3407
PRKACB	-1429	2885
PRKAG1	3836	7302
PRKAG2	375	740
PRKAR1A	4	6
PRKAR1B	-1038	2113
PRKAR2A	-860	1753
PRKCA	2439	4709
PRKCD	-5638	11872
PRKCE	-5510	11606
PRKCH	-1569	3185
PRKCI	-826	1681
PRKCZ	-6584	13676
PRKX	-553	1134
PRMT1	-4281	9055
PRR5	-2094	4323
PSAP	-5218	11023
PSEN1	-4938	10427
PSEN2	-2559	5310
PSENEN	-2327	4828
PSMA1	-5730	12052
PSMA2	-5801	12203
PSMA3	-3078	6422
PSMA4	-4211	8902
PSMA5	-2715	5657
PSMA6	-126	261
PSMA7	-892	1820
PSMB1	1054	2062
PSMB10	423	838
PSMB2	1876	3678
PSMB3	-1915	3928
PSMB4	-1144	2330
PSMB5	-742	1484
PSMB6	-4888	10326
PSMB7	-4372	9253
PSMB9	5491	10430
PSMC1	-5564	11724
PSMC2	-2389	4948
PSMC3	-1509	3070
PSMC4	-4808	10196
PSMC5	-4091	8646
PSMC6	-4878	10307
PSMD1	-5351	11280
PSMD10	4933	9356
PSMD11	-432	879
PSMD12	4303	8163
PSMD13	-2577	5353
PSMD14	5974	11371
PSMD2	-6435	13423
PSMD3	-5535	11655
PSMD4	4567	8670
PSMD5	5116	9676
PSMD6	-5951	12502
PSMD7	4942	9371
PSMD8	-2928	6091
PSMD9	-4638	9853
PSME1	-2348	4861
PSME2	-5481	11555
PSME3	-3813	8052
PSME4	-6450	13450
PSMF1	-6663	13810
PSPN	-5177	10939
PTAFR	4486	8514
PTBP1	-6035	12672
PTCH1	-1712	3498
PTCH2	6287	11989
PTEN	-4721	10023
PTENP1	-5107	10778
PTGDR2	6780	12978
PTGES3	3734	7103
PTHLH	-6042	12681
PTK2	-4346	9198
PTK2B	6809	13043
PTK6	3304	6358
PTPN1	3622	6909
PTPN11	-867	1770
PTPN12	-5326	11236
PTPN18	6851	13128
PTPN2	-3809	8048
PTPN3	-6738	13930
PTPN6	6557	12513
PTPRA	815	1606
PTPRJ	-6103	12791
PTPRK	-6199	12980
PTPRS	397	779
PTPRU	4441	8430
PXN	2548	4926
PYGO1	3963	7518
PYGO2	1616	3187
RAB4A	-2148	4453
RAB4B	3174	6116
RAB6A	1296	2578
RAB7A	-5810	12220
RAB9A	-6014	12633
RAC1	44	95
RAC3	1423	2837
RACGAP1	5789	10990
RACK1	-4287	9064
RAD21	601	1178
RAF1	-5557	11708
RALA	-6548	13623
RALB	270	524
RALBP1	-992	2026
RALGAPA1	-1001	2044
RALGDS	4617	8765
RAMP1	-7037	14385
RAMP2	6288	11990
RANBP10	-1342	2698
RANBP2	-4	9
RANBP9	-6871	14151
RANGAP1	3458	6615
RAP1A	309	604
RAP1B	3577	6830
RAP1GDS1	-5198	10985
RAPGEF1	-6586	13680
RAPGEF2	-6716	13897
RAPGEF4	438	863
RARA	-6269	13109
RARG	173	335
RASA1	2559	4950
RASA2	817	1608
RASA4	-277	567
RASAL2	2019	3937
RASGEF1A	-290	596
RASGRF1	1900	3721
RASGRF2	-5955	12510
RASGRP3	-569	1164
RBBP4	-3297	6938
RBBP5	-101	204
RBBP6	-6244	13058
RBBP7	5134	9712
RBCK1	-2891	6012
RBFOX2	1286	2561
RBL1	4660	8842
RBMX	-5221	11027
RBPJ	4794	9099
RBX1	-3714	7850
RCC2	-5709	12011
RCE1	-1124	2289
RCOR1	-3493	7376
RDH10	-6134	12847
RDH11	6369	12131
RDH13	-415	839
RDH14	-3592	7587
RDH16	1613	3180
RDH5	5315	10055
RELA	-2632	5468
REST	-593	1214
RFNG	-1510	3072
RGL1	-5600	11795
RGL2	-3017	6290
RGL3	6456	12308
RGS10	-1881	3858
RGS12	-4241	8968
RGS14	-5515	11616
RGS19	-1130	2301
RGS2	1680	3297
RGS3	-4893	10335
RGS5	6561	12517
RGS9	2861	5517
RHEB	-3762	7936
RHOA	-5294	11182
RHOB	6064	11537
RHOBTB1	5975	11372
RHOBTB2	7276	14141
RHOBTB3	-6640	13761
RHOC	-6747	13943
RHOD	1302	2596
RHOF	-2600	5403
RHOG	-2756	5747
RHOH	49	103
RHOJ	-2522	5241
RHOQ	-6969	14296
RHOT1	4106	7793
RHOT2	515	1020
RHOU	4579	8693
RHPN1	6595	12589
RHPN2	1950	3804
RICTOR	-2076	4274
RING1	4067	7710
RIPK1	-2886	6000
RIPK2	-5779	12158
RIT1	-5298	11188
RND1	-1410	2828
RNF111	2443	4714
RNF146	825	1622
RNF2	2454	4732
RNF20	5837	11085
RNF31	227	445
RNF41	6188	11780
RNF43	1197	2353
ROCK1	-3594	7591
ROCK2	-2772	5775
ROR1	-4544	9638
RPGRIP1L	6834	13101
RPS27	-152	312
RPS27A	-2773	5776
RPS6	-2681	5569
RPS6KA1	-3857	8159
RPS6KA2	-1149	2339
RPS6KA3	-3030	6316
RPS6KA5	3086	5949
RPS6KB1	-3622	7667
RPS6KB2	-3901	8241
RPTOR	407	803
RRAD	-5988	12580
RRAGA	2609	5038
RRAGB	-4819	10211
RRAGC	-7009	14345
RRAGD	-6743	13938
RRAS2	-4979	10503
RTKN	-5834	12273
RTN4	-4643	9862
RUNX1	-7020	14359
RUNX3	-342	698
RUVBL1	5317	10058
RXFP4	-6443	13440
RXRA	-4073	8607
RXRB	878	1725
RYK	-2525	5246
S1PR2	215	421
S1PR3	194	374
SALL4	6934	13298
SAMM50	-5117	10805
SAV1	-3212	6741
SCAI	4892	9277
SCD	6981	13413
SCFD1	485	960
SCMH1	6656	12722
SCRIB	-2641	5488
SEC13	-6812	14049
SEH1L	-4472	9474
SEL1L	-7124	14508
SEM1	-3130	6566
SEMA4F	7059	13579
SENP1	-886	1811
SERPINE1	5901	11217
SFN	-4169	8812
SFPQ	-6854	14118
SGK1	865	1698
SGO1	2010	3925
SGO2	5279	9987
SH2B1	-3615	7640
SH2B2	1149	2259
SH2B3	-4752	10091
SH2D2A	5820	11047
SH3BP1	-95	196
SH3GL1	-4200	8879
SH3KBP1	-917	1864
SH3PXD2A	-5496	11583
SH3RF1	-6212	13005
SHARPIN	3128	6027
SHB	-7035	14382
SHC1	-6910	14209
SHC2	-5479	11550
SHC3	-3782	7979
SHH	-3305	6953
SHKBP1	3221	6194
SHMT2	-6143	12864
SHOC2	-749	1499
SIN3A	-5884	12373
SIRT6	-2510	5203
SKA1	4823	9144
SKA2	6507	12421
SKI	-1777	3621
SKIL	-3659	7744
SKP1	-544	1117
SLC1A5	-5969	12542
SLC38A9	-5539	11664
SLC4A7	3094	5963
SLITRK5	1437	2858
SLK	-5147	10872
SMAD1	4977	9435
SMAD2	-4087	8639
SMAD3	-6145	12871
SMAD4	2742	5290
SMAD5	1543	3047
SMAD6	-476	964
SMAD7	3117	6006
SMAD9	6128	11670
SMARCA4	-3226	6773
SMC1A	784	1560
SMC3	2546	4924
SMO	2649	5118
SMPD2	417	823
SMPD3	874	1715
SMURF1	-6229	13034
SMURF2	-5253	11093
SNAI1	-4674	9927
SNAP23	-5681	11956
SNW1	-5581	11762
SNX3	-4858	10279
SOCS1	5053	9561
SOCS3	7374	14476
SOCS6	-5467	11523
SOS1	-950	1928
SOS2	-5417	11402
SOWAHC	-5665	11934
SOX13	1115	2184
SOX4	-3727	7867
SOX6	-307	637
SOX7	-497	1003
SOX9	7103	13716
SP1	-5412	11396
SPARC	1607	3167
SPATA13	-5931	12459
SPC24	7021	13498
SPDL1	6715	12856
SPEN	-6197	12976
SPHK1	-3142	6587
SPINT1	-3991	8433
SPINT2	-632	1286
SPOP	-3272	6873
SPOPL	-212	435
SPP1	-5872	12355
SPPL2A	-4568	9693
SPPL2B	2936	5650
SPRED1	-2574	5348
SPRED2	-2862	5946
SPRED3	-3905	8248
SPRY1	-1918	3939
SPRY2	-1990	4083
SPTAN1	2385	4610
SPTBN1	-4901	10356
SPTBN2	3883	7379
SQSTM1	-7010	14347
SRC	3962	7516
SREBF1	-3554	7517
SRF	-3090	6447
SRGAP1	-1796	3662
SRGAP2	-1779	3627
SRGAP3	6775	12970
SRRM1	-354	723
SRY	5473	10390
SSTR2	-2650	5508
SSTR3	6553	12506
SSTR5	2225	4318
ST3GAL3	5918	11257
ST3GAL4	-6801	14033
ST3GAL6	-3252	6829
STAG1	-3341	7037
STAG2	-2617	5443
STAM	5109	9665
STAM2	3080	5933
STAP2	4664	8852
STARD13	-6024	12646
STARD8	571	1115
STAT1	-5668	11938
STAT3	4253	8078
STAT5A	5288	10000
STAT5B	6572	12541
STAT6	-1541	3128
STBD1	-3361	7077
STEAP3	-6993	14327
STIP1	-3571	7550
STK10	333	642
STK11	-3146	6595
STK3	-207	428
STK38	-3810	8049
STK4	3459	6620
STMN1	2680	5180
STOM	-1523	3093
STRADA	6661	12729
STRADB	3307	6364
STRAP	-4142	8749
STRN	-5363	11300
STUB1	3373	6475
STX5	-5300	11191
SUFU	2576	4979
SUZ12	346	664
SWAP70	-3097	6466
SYDE1	5815	11040
SYDE2	2107	4108
SYNGAP1	2484	4797
SYVN1	-7108	14485
TAB1	6687	12789
TAB2	-3878	8201
TAB3	2566	4960
TACC3	3154	6081
TAOK1	-2864	5951
TAOK3	-3324	6995
TAS1R1	2471	4764
TAS1R3	-3182	6672
TAS2R4	5037	9532
TAS2R5	6569	12532
TAX1BP1	-6281	13141
TAX1BP3	-2489	5154
TBL1X	-1621	3308
TBL1XR1	1404	2795
TBP	3968	7524
TBXA2R	1137	2235
TCF12	-3164	6626
TCF7	-6556	13636
TCF7L1	3414	6533
TCF7L2	959	1893
TCIRG1	180	348
TERT	4560	8656
TEX2	793	1573
TF	5850	11111
TFDP1	-2579	5361
TFDP2	4856	9210
TFF1	2618	5067
TFF3	7324	14289
TFRC	-6637	13755
TGFA	-4511	9574
TGFB1	-6934	14241
TGFBR1	-2620	5447
TGFBR2	-3644	7714
TGIF1	2034	3964
TGIF2	-798	1624
THBS1	5988	11408
THBS2	2512	4856
THBS3	4450	8446
THBS4	7170	13862
THEM4	6080	11571
TIA1	6310	12027
TIAL1	-4432	9377
TIAM1	4452	8451
TIAM2	-3267	6863
TJP1	-4801	10173
TJP2	6225	11851
TLE1	-2800	5826
TLE2	5001	9473
TLE3	-5003	10548
TLE4	-6478	13500
TLN1	-6146	12872
TLR9	-2371	4913
TMED2	-7071	14433
TMED5	-4243	8971
TMEM59	-6370	13311
TMEM87A	-5423	11413
TMOD3	2983	5728
TMPO	6967	13363
TNFAIP1	5996	11426
TNFAIP3	4359	8284
TNFRSF10A	-4397	9306
TNFRSF10B	-6645	13770
TNFRSF10D	-5009	10566
TNFRSF1A	4807	9118
TNFSF10	5424	10292
TNKS	-4790	10153
TNKS2	-3213	6742
TNRC6A	1824	3580
TNRC6B	-4212	8904
TNRC6C	-4805	10180
TNS3	-3893	8224
TNS4	-3726	7866
TOR1AIP1	-5699	11985
TP53	-2020	4144
TPH1	4694	8911
TPM3	-40	71
TPM4	-822	1674
TRA2B	-1257	2539
TRADD	3885	7383
TRAF1	2688	5192
TRAF2	-577	1180
TRAF6	1597	3150
TRAK1	3646	6949
TRAK2	1119	2191
TRIB1	5404	10234
TRIB3	-6798	14029
TRIM27	-4835	10241
TRIM33	-5413	11397
TRIO	-5341	11264
TRIP10	4417	8370
TRRAP	-3581	7571
TSC1	-5024	10605
TSC2	-2462	5097
TTC21B	4480	8500
TUBA1B	7094	13681
TULP3	-1209	2451
TWF1	-4167	8810
TXNL1	-4076	8617
TYK2	5066	9579
UACA	5249	9918
UBA52	-5068	10707
UBB	-4263	9013
UBC	779	1551
UBE2D1	3523	6734
UBE2D3	-3997	8449
UBE2M	-4337	9174
UBXN11	6442	12284
UCHL5	443	875
UCN	5800	11013
UCN2	-3575	7561
UHMK1	-3687	7794
UHRF1BP1L	-4128	8723
ULK3	4342	8247
USF1	-2194	4545
USF2	-5900	12399
USP13	6054	11521
USP15	-4344	9193
USP2	-5430	11427
USP21	2804	5405
USP34	-4441	9391
USP4	1449	2874
USP7	134	258
USP8	-2820	5864
USP9X	-4318	9136
UTS2B	2923	5630
VAMP3	-698	1415
VANGL1	-4152	8782
VANGL2	3723	7088
VAPA	-4898	10346
VAPB	3551	6785
VAV2	2817	5425
VAV3	-4642	9861
VCL	4407	8357
VCP	-6720	13902
VEGFA	-4456	9433
VEGFB	-6562	13646
VGF	-6864	14140
VHL	-6491	13531
VPS26A	-4841	10251
VPS29	494	977
VPS35	-3006	6275
VRK2	-6520	13580
VRK3	-1278	2573
VWF	1933	3777
WASF1	-5712	12021
WASF2	-3366	7096
WASF3	2619	5070
WASL	-6543	13611
WDR11	3445	6588
WDR19	-1802	3682
WDR35	2156	4193
WDR6	-1254	2528
WDR81	-4080	8629
WDR83	-3643	7711
WDR91	4363	8290
WHAMM	-5798	12191
WIPF2	-2965	6174
WNT11	3642	6940
WNT2B	-4408	9328
WNT3	-2666	5541
WNT6	2412	4663
WNT7B	-4849	10260
WWC1	-789	1596
WWOX	-1477	2994
WWP1	-779	1572
WWP2	-5151	10881
WWTR1	-271	555
XCL1	3488	6670
XIAP	-2929	6096
XPO1	-1864	3824
YAP1	2171	4225
YBX1	-5615	11834
YES1	-1340	2690
YKT6	-4899	10349
YWHAB	2082	4062
YWHAE	129	253
YWHAG	-1018	2081
YWHAH	-3511	7417
YWHAQ	542	1061
YWHAZ	-885	1810
YY1	-5214	11015
ZAP70	-5027	10613
ZDHHC21	4413	8365
ZDHHC7	-5954	12508
ZDHHC9	-5497	11585
ZFYVE16	4169	7925
ZFYVE9	1407	2801
ZNF217	6814	13059
ZNF512B	-4669	9920
ZNRF3	-5742	12093
ZRANB1	-5895	12391
ZW10	-4054	8564
ZWILCH	6246	11891
ZWINT	5984	11400

---

---

Unfolded Protein Response (UPR)

Unfolded Protein Response (UPR)

metric	value
setSize	89
pMANOVA	3.68e-17
p.adjustMANOVA	7.23e-15
s.dist	0.544
s.x	-0.393
s.abs	0.376
p.x	1.43e-10
p.abs	9.26e-10

Top 20 genes

Gene	x	abs
HSPA5	-7144	14531
CALR	-7142	14529
DNAJB11	-7141	14528
HYOU1	-7140	14527
HERPUD1	-7137	14524
DNAJC3	-7131	14516
HSP90B1	-7129	14514
DNAJB9	-7125	14510
SYVN1	-7108	14485
PDIA6	-7106	14482
EDEM1	-7103	14479
WFS1	-7096	14466
GFPT1	-7051	14406
DDIT3	-7047	14401
EIF2AK3	-7028	14371
MYDGF	-6976	14306
SERP1	-6964	14288
ATF6	-6949	14261
WIPI1	-6942	14251
SHC1	-6910	14209

Click HERE to show all gene set members

All member genes

	x	abs
ACADVL	4157	7903
ADD1	-5966	12538
ARFGAP1	-1587	3224
ASNS	6208	11814
ATF3	2488	4803
ATF4	-5664	11932
ATF6	-6949	14261
ATP6V0D1	-6908	14206
CALR	-7142	14529
CEBPB	-1129	2300
CEBPG	-5987	12578
CREB3	-3650	7725
CREB3L2	-6832	14080
CREB3L3	5999	11433
CREB3L4	5920	11259
CREBRF	-4582	9731
CTDSP2	-4462	9444
CUL7	4377	8310
CXCL8	3625	6916
CXXC1	-6033	12670
DCP2	-5125	10825
DCTN1	-1635	3338
DDIT3	-7047	14401
DDX11	6254	11907
DIS3	-1573	3190
DNAJB11	-7141	14528
DNAJB9	-7125	14510
DNAJC3	-7131	14516
EDEM1	-7103	14479
EIF2AK3	-7028	14371
EIF2S1	-5190	10961
EIF2S2	-4458	9437
EIF2S3	-3669	7757
ERN1	-6872	14152
EXOSC1	3486	6667
EXOSC2	3779	7192
EXOSC3	-3453	7270
EXOSC4	3220	6193
EXOSC5	-4766	10117
EXOSC6	-6503	13547
EXOSC7	5196	9819
EXOSC8	472	928
EXOSC9	3293	6333
EXTL1	6941	13312
EXTL2	3353	6440
EXTL3	3575	6822
FKBP14	-6896	14184
GFPT1	-7051	14406
GOSR2	1238	2441
GSK3A	-3684	7787
HDGF	-6715	13896
HERPUD1	-7137	14524
HSP90B1	-7129	14514
HSPA5	-7144	14531
HYOU1	-7140	14527
IGFBP1	-3931	8301
KDELR3	976	1922
KHSRP	-994	2029
KLHDC3	-3802	8036
LMNA	-3717	7854
MBTPS1	-5958	12523
MBTPS2	3687	7019
MYDGF	-6976	14306
NFYA	-2482	5142
NFYB	5091	9634
NFYC	-690	1395
PARN	-4578	9715
PDIA5	579	1130
PDIA6	-7106	14482
PLA2G4B	4716	8953
PPP2R5B	-5131	10834
PREB	1446	2868
SEC31A	-5766	12138
SERP1	-6964	14288
SHC1	-6910	14209
SRPRA	-4802	10175
SRPRB	-6893	14181
SSR1	-6907	14205
SULT1A3	1040	2038
SYVN1	-7108	14485
TATDN2	-6467	13480
TLN1	-6146	12872
TPP1	-6407	13378
TSPYL2	-6784	14002
WFS1	-7096	14466
WIPI1	-6942	14251
XBP1	5937	11302
YIF1A	195	381
ZBTB17	-3194	6703

---

---

SRP-dependent cotranslational protein targeting to membrane

SRP-dependent cotranslational protein targeting to membrane

metric	value
setSize	109
pMANOVA	1.6e-16
p.adjustMANOVA	2.75e-14
s.dist	0.473
s.x	-0.473
s.abs	0.0229
p.x	1.48e-17
p.abs	0.68

Top 20 genes

Gene	x	abs
SEC61A1	-7030	14374
RPN1	-7013	14350
SSR4	-7004	14338
TRAM1	-6997	14331
SEC11C	-6991	14325
RPL36AL	-6981	14313
SEC61B	-6958	14278
SSR3	-6928	14235
SSR1	-6907	14205
SRPRB	-6893	14181
SPCS3	-6781	13996
SSR2	-6759	13968
DDOST	-6429	13410
SRP68	-6420	13394
SRP19	-6363	13297
RPN2	-6193	12964
SRP14	-5938	12470
SPCS2	-5930	12458
SRP72	-5526	11640
RPL19	-5254	11094

Click HERE to show all gene set members

All member genes

	x	abs
DDOST	-6429	13410
FAU	-4990	10520
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPN1	-7013	14350
RPN2	-6193	12964
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
SEC11A	-3046	6345
SEC11C	-6991	14325
SEC61A1	-7030	14374
SEC61A2	-1397	2808
SEC61B	-6958	14278
SEC61G	-4052	8561
SPCS1	2416	4672
SPCS2	-5930	12458
SPCS3	-6781	13996
SRP14	-5938	12470
SRP19	-6363	13297
SRP54	-1969	4041
SRP68	-6420	13394
SRP72	-5526	11640
SRP9	5604	10650
SRPRA	-4802	10175
SRPRB	-6893	14181
SSR1	-6907	14205
SSR2	-6759	13968
SSR3	-6928	14235
SSR4	-7004	14338
TRAM1	-6997	14331
UBA52	-5068	10707

---

---

Metabolism of proteins

Metabolism of proteins

metric	value
setSize	1550
pMANOVA	1.4e-15
p.adjustMANOVA	2.15e-13
s.dist	0.13
s.x	-0.118
s.abs	0.0556
p.x	3.25e-14
p.abs	0.00034

Top 20 genes

Gene	x	abs
CALR	-7142	14529
RAB17	-7135	14521
SEC24D	-7134	14520
DNAJC3	-7131	14516
HSP90B1	-7129	14514
SEL1L	-7124	14508
SELENOS	-7117	14498
SYVN1	-7108	14485
PDIA6	-7106	14482
EDEM1	-7103	14479
WFS1	-7096	14466
KLF4	-7093	14463
CANX	-7092	14462
PDIA3	-7086	14454
ERO1B	-7079	14442
SLC17A5	-7072	14434
TMED2	-7071	14433
KLHL21	-7069	14429
MCFD2	-7065	14425
ARRB1	-7062	14420

Click HERE to show all gene set members

All member genes

	x	abs
AAAS	2965	5701
AARS2	5743	10908
ABCA3	3033	5842
ACE2	2757	5319
ACHE	-1152	2348
ACTB	-5057	10683
ACTL6A	-1378	2772
ACTR10	5570	10590
ACTR1A	-5162	10903
ACTR5	4150	7892
ACTR8	-3157	6616
ADAM10	-2671	5549
ADAMTS1	3770	7179
ADAMTS10	6971	13383
ADAMTS13	5043	9541
ADAMTS17	-2445	5058
ADAMTS2	6939	13309
ADAMTS4	1241	2448
ADAMTS6	6501	12405
ADAMTS7	2880	5554
ADAMTS9	6402	12207
ADAMTSL2	-3475	7330
ADAMTSL3	2956	5688
ADAMTSL4	7040	13538
ADAMTSL5	-1090	2224
ADORA2A	5330	10081
ADORA2B	5127	9698
ADRA2C	-6434	13422
ADRM1	-3551	7511
AFP	-4151	8777
AGBL2	5191	9809
AGBL3	1865	3660
AGBL5	2606	5032
AGT	7091	13674
AGTPBP1	5818	11045
AHSG	25	62
AIMP1	1790	3508
AIMP2	1067	2099
ALB	3096	5965
ALG1	-4352	9207
ALG10	2654	5133
ALG10B	5899	11213
ALG11	-5957	12520
ALG12	-6081	12752
ALG13	1348	2687
ALG14	-3206	6723
ALG2	-6554	13631
ALG3	-6601	13700
ALG5	-6471	13488
ALG6	4943	9374
ALG8	1117	2188
ALG9	-426	865
AMDHD2	5414	10267
AMFR	-2698	5612
ANK1	-4656	9901
ANK2	-6778	13993
ANK3	303	591
ANKRD28	4146	7882
ANKRD9	2692	5202
ANO8	-168	350
ANPEP	4690	8901
AP3M1	3816	7269
APC	-1818	3716
APEH	4698	8922
APH1A	619	1209
APH1B	6168	11741
APLP2	-3330	7009
APOA1	6993	13433
APOA2	-6307	13191
APOA4	226	444
APOA5	4116	7816
APOB	-2964	6172
APOE	-3670	7759
APOL1	4896	9284
APP	-6492	13532
ARCN1	-6505	13549
AREG	-4847	10258
ARF1	-6021	12642
ARF3	-2430	5040
ARF4	-5812	12225
ARF5	4743	8998
ARFGAP1	-1587	3224
ARFGAP2	1283	2547
ARFGAP3	-4817	10209
ARFGEF2	1022	2008
ARL2	5716	10857
ARRB1	-7062	14420
ARRB2	-3248	6824
ARSA	2878	5552
ARSB	-6939	14246
ARSD	-4527	9613
ARSG	7341	14366
ARSI	6118	11653
ARSK	-1251	2519
ART4	6681	12770
ASB1	-4171	8818
ASB13	6386	12175
ASB18	-601	1231
ASB2	-6960	14280
ASB3	3026	5827
ASB4	-3822	8067
ASB6	-5243	11077
ASB7	-3889	8217
ASB8	-1103	2243
ASB9	5150	9735
ASGR1	-1889	3870
ASGR2	-2985	6225
ASXL1	-1908	3914
ASXL2	-5845	12292
ATP6AP2	-1245	2508
ATXN3	3714	7075
ATXN7	-4932	10416
AURKA	1224	2412
AURKAIP1	-5100	10765
AURKB	6883	13190
AXIN1	-4215	8908
AXIN2	-5745	12097
B2M	-2523	5242
B3GALNT2	-2427	5034
B3GLCT	-5422	11411
B3GNT2	-2359	4879
B3GNT3	4629	8781
B3GNT4	-1829	3741
B3GNT7	1584	3122
B3GNT8	3574	6820
B3GNT9	-4301	9094
B3GNTL1	1392	2766
B4GALNT2	1387	2758
B4GALT1	-262	540
B4GALT2	-2487	5152
B4GALT3	-4852	10265
B4GALT4	2602	5027
B4GALT5	6846	13121
B4GALT6	2881	5555
B4GAT1	-3691	7803
BABAM1	2979	5721
BACE1	6090	11590
BAP1	-2760	5752
BARD1	6138	11687
BCL10	-4471	9472
BECN1	-2900	6036
BET1	457	896
BET1L	3487	6669
BGLAP	241	475
BIRC2	-499	1007
BIRC3	3477	6654
BIRC5	5174	9771
BLM	5994	11423
BMI1	-4180	8838
BMP4	-6869	14148
BPIFB2	-4967	10473
BRCA1	5107	9663
BRCC3	2358	4560
BST1	713	1408
BTBD1	37	81
BTRC	1386	2757
C1GALT1	742	1485
C1GALT1C1	-2939	6112
C3	7357	14417
C4A	7346	14381
CALB1	1461	2895
CALM1	-655	1340
CALR	-7142	14529
CALU	-4521	9602
CAMKMT	962	1898
CAND1	-1658	3381
CANX	-7092	14462
CAPZA1	-4855	10272
CAPZA2	-1549	3143
CAPZB	-1169	2376
CARS2	2078	4056
CASP8AP2	5260	9946
CBX2	6958	13350
CBX4	-4063	8580
CBX5	7222	14012
CBX8	-4370	9242
CCDC22	-1703	3481
CCDC59	-4775	10132
CCDC8	2470	4762
CCNA2	6594	12587
CCNE1	2754	5315
CCNE2	-2024	4152
CCNF	1291	2569
CCP110	6203	11807
CCT2	-5926	12444
CCT3	-2912	6052
CCT4	-1418	2852
CCT5	-6251	13070
CCT6A	-5862	12336
CCT6B	563	1100
CCT7	-1465	2974
CCT8	-5605	11813
CD109	-5016	10579
CD55	-6517	13575
CD59	-3245	6818
CDC20	5650	10732
CDC25A	5954	11334
CDC34	-5516	11619
CDC73	-4683	9943
CDCA8	6649	12700
CDH2	-2339	4845
CDK1	7230	14027
CDKN2A	3704	7056
CEACAM5	1008	1981
CES1	7025	13506
CETN2	5801	11018
CHCHD1	1058	2069
CHD3	-1321	2661
CHGB	2226	4319
CHM	5425	10293
CHML	1746	3428
CHST10	6919	13262
CISH	6003	11440
CKAP4	-3939	8327
CLSPN	7014	13484
CMAS	5724	10871
CNIH1	212	416
CNIH3	-1958	4025
COG1	4586	8708
COG2	-4254	8997
COG3	-5948	12497
COG4	1972	3852
COG5	-3964	8389
COG6	3264	6266
COG7	4792	9093
COG8	6745	12910
COL7A1	5362	10152
COMMD1	4304	8164
COMMD10	117	233
COMMD2	395	774
COMMD3	4983	9446
COMMD4	-2	7
COMMD5	-4916	10389
COMMD6	5668	10773
COMMD7	5185	9798
COMMD8	710	1404
COMMD9	-3531	7455
COPA	-3958	8376
COPB1	-4098	8664
COPB2	-6532	13594
COPE	-5961	12527
COPG1	-5135	10840
COPG2	6142	11691
COPS2	-5161	10902
COPS3	-4618	9810
COPS4	-28	51
COPS5	-3031	6317
COPS6	-3063	6380
COPS7A	5653	10738
COPS7B	-839	1713
COPS8	-4894	10337
COPZ1	782	1554
CP	7325	14292
CPB2	4337	8234
CPE	-5338	11255
CPM	1144	2250
CREBBP	-3888	8214
CSF1	-6711	13888
CSF2RA	43	94
CSNK1D	-5722	12038
CSNK2A1	-5040	10637
CSNK2A2	-4546	9641
CSNK2B	4415	8368
CST3	3732	7101
CTBP1	-41	73
CTNNB1	3272	6288
CTR9	-3895	8230
CTSA	-6288	13149
CTSC	-4446	9398
CTSD	2812	5416
CTSH	5655	10743
CUL1	-4129	8725
CUL2	359	703
CUL3	-3056	6363
CUL4A	-2265	4702
CUL4B	-4685	9945
CUL5	-1229	2485
CUL7	4377	8310
CUL9	6773	12968
CYLD	-6066	12727
CYR61	-2582	5367
DAD1	-6240	13053
DAG1	-2174	4498
DAP3	972	1917
DARS2	2466	4756
DAXX	3635	6929
DCAF10	-5421	11410
DCAF11	-6142	12860
DCAF13	4652	8826
DCAF16	5344	10105
DCAF17	3819	7273
DCAF4	5420	10278
DCAF5	-4547	9642
DCAF6	-2469	5119
DCAF7	5557	10568
DCAF8	4645	8816
DCTN1	-1635	3338
DCTN2	-3957	8375
DCTN3	1457	2887
DCTN4	-1937	3979
DCTN5	-3634	7690
DCTN6	-318	666
DCUN1D1	1428	2843
DCUN1D2	-4601	9784
DCUN1D3	-5821	12244
DCUN1D4	-400	815
DCUN1D5	-1895	3884
DDA1	-5633	11862
DDB1	-5688	11967
DDB2	6754	12925
DDOST	-6429	13410
DDX17	-3321	6985
DDX5	-6665	13814
DDX58	-927	1883
DERL1	-6423	13398
DERL2	-7046	14399
DHDDS	2399	4636
DHPS	3475	6649
DNAJC24	2574	4977
DNAJC3	-7131	14516
DNMT1	2134	4159
DNMT3A	3360	6452
DNMT3B	6957	13348
DOHH	-4258	9002
DOLK	108	213
DOLPP1	-4988	10517
DPAGT1	-6046	12688
DPH1	-5397	11373
DPH2	-5629	11858
DPH3	-5074	10720
DPH5	6731	12882
DPH6	5513	10486
DPH7	-2301	4778
DPM1	-1233	2494
DPM2	-2111	4373
DPM3	3217	6189
DPP4	-6681	13845
DTL	4577	8690
DYNC1H1	-3614	7639
DYNC1I2	-2780	5783
DYNC1LI1	-2519	5237
DYNC1LI2	-3897	8235
DYNLL1	2509	4853
DYNLL2	6044	11507
EARS2	1253	2477
EDEM1	-7103	14479
EDEM2	-5520	11628
EDEM3	-1903	3904
EEF1A1	-4138	8740
EEF1A1P5	-1745	3558
EEF1A2	553	1086
EEF1B2	-4836	10243
EEF1D	-5115	10800
EEF1E1	-4013	8489
EEF1G	-3612	7628
EEF2	-5049	10659
EEF2KMT	867	1703
EID3	-2695	5599
EIF1AX	-274	563
EIF2B1	-143	293
EIF2B2	-4811	10200
EIF2B3	5203	9835
EIF2B4	437	862
EIF2B5	-4838	10248
EIF2S1	-5190	10961
EIF2S2	-4458	9437
EIF2S3	-3669	7757
EIF3A	-6965	14290
EIF3B	-5127	10829
EIF3C	-374	764
EIF3D	-3740	7889
EIF3E	3244	6234
EIF3F	-893	1821
EIF3G	-4724	10029
EIF3H	899	1763
EIF3I	-5279	11151
EIF3J	-4539	9629
EIF3K	-2206	4569
EIF3L	-2407	4991
EIF3M	-4358	9224
EIF4A1	-6995	14329
EIF4A2	5593	10631
EIF4B	-5898	12396
EIF4E	2473	4766
EIF4EBP1	4858	9212
EIF4G1	-5901	12400
EIF4H	-5055	10679
EIF5	-6065	12721
EIF5A	-5678	11952
EIF5A2	-4929	10412
EIF5B	3318	6386
ELOB	-3004	6272
ELOC	645	1265
ENGASE	6457	12309
EP300	-6470	13485
EPAS1	-4915	10387
ERAL1	2351	4546
ERCC8	-2409	4995
ERO1A	-198	403
ERO1B	-7079	14442
ETF1	-6952	14268
ETFB	2051	4002
ETFBKMT	3805	7248
EVA1A	-4709	9995
EXOC1	6302	12013
EXOC2	-747	1496
EXOC3	-3898	8237
EXOC4	1053	2059
EXOC5	337	650
EXOC6	2506	4847
EXOC7	3531	6748
EXOC8	-92	189
F10	5732	10888
F2	635	1246
F5	831	1638
F7	6332	12069
F8	735	1460
FAM20A	7332	14315
FAM20C	4945	9378
FARS2	1328	2645
FARSA	-2976	6205
FARSB	3269	6282
FAU	-4990	10520
FBN1	7148	13813
FBXL12	-1137	2320
FBXL13	-870	1783
FBXL14	-2614	5439
FBXL15	612	1200
FBXL16	7269	14129
FBXL18	-1507	3067
FBXL19	-2110	4369
FBXL20	-3941	8336
FBXL22	3108	5990
FBXL3	-2027	4168
FBXL4	4801	9111
FBXL5	5669	10775
FBXL8	2924	5631
FBXO10	18	43
FBXO11	-3853	8152
FBXO15	3559	6797
FBXO17	5986	11405
FBXO2	-78	158
FBXO21	4978	9436
FBXO22	4762	9038
FBXO27	3623	6911
FBXO30	137	270
FBXO31	-5485	11563
FBXO32	-5299	11189
FBXO4	4180	7948
FBXO41	6136	11685
FBXO44	-4694	9964
FBXO6	3932	7468
FBXO7	947	1865
FBXO9	-1843	3776
FBXW10	-2540	5268
FBXW11	-3784	7986
FBXW2	-294	602
FBXW4	6039	11502
FBXW5	-5945	12489
FBXW7	-2564	5325
FBXW8	3716	7078
FBXW9	890	1747
FEM1A	-1576	3196
FEM1B	-103	209
FEM1C	-4764	10115
FGA	7336	14346
FGF23	2097	4091
FGG	6697	12809
FKBP8	6242	11886
FKBP9	7108	13730
FN1	-3115	6525
FN3K	1324	2638
FN3KRP	6434	12265
FOXK1	-4324	9151
FOXK2	-6570	13656
FOXO4	-2077	4276
FPGT	5627	10685
FSTL3	-5252	11092
FUCA1	2696	5210
FUCA2	-6538	13600
FUOM	2573	4976
FURIN	-6683	13851
FUT3	-7001	14335
FUT8	-5134	10839
GADD45GIP1	-3917	8274
GALNT1	-816	1659
GALNT10	-4763	10114
GALNT11	7125	13771
GALNT13	-810	1646
GALNT16	2794	5384
GALNT2	6578	12555
GALNT3	-3227	6774
GALNT4	2438	4706
GALNT6	4939	9366
GALNT7	-4049	8555
GAN	-3641	7702
GANAB	2813	5417
GAS6	2708	5226
GATA4	-6369	13306
GATA6	2495	4816
GBA	-6674	13831
GBF1	-4981	10507
GCNT1	679	1328
GCNT3	-7052	14407
GCNT4	3690	7025
GFM1	-2827	5882
GFM2	-2567	5337
GFPT1	-7051	14406
GGA1	2520	4881
GGA2	-6138	12852
GGA3	4199	7982
GGCX	-4023	8504
GLB1	1557	3064
GMDS	-3350	7053
GMPPA	-6346	13267
GMPPB	-6844	14096
GNA11	-5916	12425
GNAQ	803	1588
GNB1	-3237	6796
GNB2	-4514	9583
GNB3	-1008	2063
GNB4	1936	3781
GNB5	700	1388
GNE	6051	11517
GNG10	6779	12977
GNG4	6164	11731
GNG5	4123	7830
GNG7	4426	8395
GNPNAT1	2394	4628
GOLGA2	-5310	11209
GOLGB1	-3498	7386
GOLM1	-4779	10136
GORASP1	1903	3727
GOSR1	621	1215
GOSR2	1238	2441
GP2	806	1595
GPAA1	-2406	4990
GPC3	4191	7971
GPLD1	-4556	9667
GPR119	-2983	6222
GPS1	-3506	7406
GSN	1496	2952
GSPT1	-6825	14070
H2AFX	5356	10131
HARS2	5687	10804
HCFC1	-6060	12714
HDAC1	-2676	5563
HDAC2	-338	693
HDAC3	38	84
HDAC4	-1478	2998
HDAC7	130	254
HERC2	-3739	7888
HGS	-4210	8898
HIC1	-2592	5389
HIF1A	-4165	8807
HIF3A	4444	8437
HIPK2	6284	11978
HLA-A	5777	10971
HLA-B	2764	5329
HLTF	6769	12961
HNRNPC	1814	3563
HNRNPK	-2808	5839
HRC	5955	11335
HSP90B1	-7129	14514
HSPA8	-4654	9895
HSPG2	7157	13832
IARS2	-1767	3601
ICMT	2988	5741
IDE	-4045	8543
IFIH1	6646	12693
IGF2	7375	14477
IGFALS	5854	11119
IGFBP1	-3931	8301
IGFBP2	6370	12133
IGFBP3	6060	11532
IGFBP4	5060	9571
IGFBP6	-2783	5787
IGFBP7	4272	8108
IKBKE	-787	1593
IKBKG	-5946	12493
INCENP	5290	10005
ING2	-711	1437
INHA	-500	1010
INHBB	-2320	4815
INHBC	2246	4351
INHBE	-4510	9570
INO80	-3397	7157
INO80B	2818	5426
INO80C	-185	380
INO80D	-3312	6967
INO80E	3921	7449
ITIH2	1740	3417
ITM2B	3727	7092
JOSD1	-5993	12588
JOSD2	3811	7257
KAT2A	5077	9597
KAT2B	-4792	10158
KBTBD6	6796	13016
KBTBD7	6772	12967
KBTBD8	2943	5662
KCTD6	-178	368
KCTD7	-3550	7510
KDELR1	-5094	10752
KDELR2	-5893	12387
KDELR3	976	1922
KDM1B	-4647	9876
KEAP1	-6482	13510
KIF13A	-4995	10525
KIF5A	-6634	13752
KIF5B	-5426	11419
KIF5C	2266	4382
KIFC3	-6237	13049
KIN	3578	6833
KLF4	-7093	14463
KLHL11	-1223	2475
KLHL13	4291	8137
KLHL2	-3269	6866
KLHL20	3344	6424
KLHL21	-7069	14429
KLHL22	5084	9610
KLHL25	-215	441
KLHL42	-4874	10303
KLHL5	-991	2025
KLHL9	3712	7071
KNG1	7382	14503
KTN1	-3223	6769
L3MBTL2	789	1567
LAMB1	3783	7198
LAMB2	495	978
LAMC1	-1300	2611
LARGE1	-5056	10682
LARGE2	-2856	5939
LARS2	6133	11681
LEO1	-3088	6444
LGALS1	-6649	13778
LMAN1	-3431	7220
LMAN2	-6558	13641
LMAN2L	-3429	7218
LMCD1	888	1745
LMO7	-1246	2512
LONP2	-6122	12828
LRR1	-494	1000
LRRC41	1992	3889
LRRC49	-625	1273
LTBP1	-1904	3905
LY6E	4473	8481
LYPD3	-297	613
LYZ	3804	7247
MAGT1	-7045	14398
MAN1A1	-1021	2084
MAN1A2	-6460	13466
MAN1B1	-3561	7534
MAN1C1	3072	5920
MAN2A1	-1040	2117
MAN2A2	-2336	4840
MANEA	4202	7987
MAP3K7	3767	7172
MARS2	1957	3819
MAT2B	1703	3339
MATN3	7298	14207
MAVS	1695	3323
MBD1	-4444	9395
MBD5	-3114	6524
MBD6	-6742	13936
MBOAT4	1368	2719
MBTPS1	-5958	12523
MCFD2	-7065	14425
MCRS1	-1472	2985
MDC1	-3323	6989
MDM2	-956	1942
MDM4	-2561	5318
MELTF	7295	14199
MEN1	1298	2581
METTL21A	5233	9883
METTL22	2346	4532
MFGE8	5552	10560
MGAT1	-6401	13371
MGAT2	-3327	7002
MGAT4A	-5018	10584
MGAT4B	-6279	13132
MGAT4C	1714	3364
MGAT5	-5854	12324
MIA3	-7049	14404
MITF	267	519
MLEC	-6902	14193
MMP2	-4677	9932
MOGS	-2275	4728
MPDU1	3718	7080
MPI	5076	9596
MRPL1	5865	11138
MRPL10	3731	7100
MRPL11	4075	7726
MRPL12	4261	8090
MRPL13	482	955
MRPL14	-4864	10287
MRPL15	1406	2798
MRPL16	5878	11164
MRPL17	5943	11317
MRPL18	-882	1806
MRPL19	96	185
MRPL2	6122	11658
MRPL20	773	1542
MRPL21	2518	4873
MRPL22	-2025	4161
MRPL23	-4800	10172
MRPL24	6982	13414
MRPL27	2747	5301
MRPL28	1039	2037
MRPL3	-5054	10675
MRPL30	5960	11343
MRPL32	-4532	9619
MRPL33	-4189	8854
MRPL34	-4611	9796
MRPL35	-4563	9685
MRPL36	-2957	6159
MRPL37	-2997	6255
MRPL38	-5234	11062
MRPL39	-2415	5007
MRPL4	-1923	3949
MRPL40	-473	956
MRPL41	-4594	9760
MRPL42	5341	10095
MRPL43	4791	9092
MRPL44	-4094	8651
MRPL46	-4455	9431
MRPL47	-4976	10494
MRPL48	-2613	5438
MRPL49	4062	7704
MRPL50	-402	818
MRPL51	-4467	9463
MRPL52	1657	3259
MRPL53	-1391	2796
MRPL54	-3013	6283
MRPL55	5826	11058
MRPL57	-2716	5658
MRPL58	1346	2678
MRPL9	-726	1463
MRPS10	-474	959
MRPS11	-2271	4718
MRPS12	-5083	10736
MRPS14	785	1561
MRPS15	-5376	11322
MRPS16	5883	11175
MRPS17	895	1758
MRPS18A	-532	1085
MRPS18B	-3346	7044
MRPS18C	-4493	9522
MRPS2	-5145	10865
MRPS21	4888	9271
MRPS22	-3909	8259
MRPS23	-2664	5535
MRPS24	-4327	9158
MRPS25	7089	13672
MRPS26	3245	6236
MRPS27	2381	4604
MRPS28	-2470	5120
MRPS30	-1657	3380
MRPS31	6190	11782
MRPS33	4704	8930
MRPS34	-2704	5623
MRPS35	-1461	2963
MRPS36	-3292	6924
MRPS5	787	1563
MRPS6	-5687	11965
MRPS7	1777	3479
MRPS9	-1007	2061
MRRF	-2721	5669
MSLN	4555	8649
MSRA	-1733	3536
MSRB1	1864	3659
MSRB2	5860	11130
MSRB3	-621	1267
MTA1	1810	3553
MTFMT	3156	6084
MTIF2	664	1307
MTIF3	-173	355
MTRF1L	-6400	13369
MUC13	-1524	3097
MUC15	4828	9153
MUC20	-1019	2082
MUC5B	7378	14487
MUL1	-5892	12386
MVD	7302	14220
MXRA8	-4064	8582
MYC	1892	3708
MYO5A	-3500	7394
MYRIP	-1341	2692
MYSM1	1066	2098
N6AMT1	7144	13806
NAE1	5740	10901
NAGK	4508	8559
NANP	483	957
NANS	-6906	14204
NAPA	-5921	12433
NAPB	-419	853
NAPG	-3872	8187
NARS2	2113	4126
NAT8	1943	3791
NCOA1	-4665	9914
NCOA2	4780	9072
NCOR2	-4409	9331
NCSTN	-554	1137
NDC1	-1490	3023
NEDD8	580	1131
NEGR1	1869	3667
NEU1	-6752	13953
NEU3	7085	13653
NEU4	6950	13335
NEURL2	2359	4562
NFKB2	-1311	2634
NFKBIA	-6437	13427
NFRKB	-4026	8510
NGLY1	-2909	6049
NICN1	4839	9177
NOD1	5449	10348
NOP56	-1145	2332
NOP58	5612	10662
NOTUM	6788	12998
NPM1	-2033	4183
NR1H2	193	373
NR1H3	4678	8878
NR1H4	-6037	12674
NR1I2	5656	10746
NR2C1	535	1052
NR3C1	-4005	8476
NR3C2	1520	2999
NR5A1	-4679	9936
NR5A2	-5547	11680
NRIP1	570	1114
NRN1L	4081	7736
NSF	-4839	10249
NSMCE1	6680	12769
NSMCE2	-4496	9534
NSMCE3	1095	2144
NSMCE4A	-1462	2966
NUB1	3894	7395
NUCB1	-5103	10770
NUDT14	-4170	8814
NUP107	6076	11561
NUP133	1362	2708
NUP153	2712	5230
NUP155	4796	9102
NUP160	-329	683
NUP188	-4991	10521
NUP205	-5275	11144
NUP210	6802	13025
NUP214	-1926	3957
NUP35	5982	11387
NUP37	7100	13706
NUP43	2808	5410
NUP50	-4733	10047
NUP54	3310	6371
NUP58	2380	4603
NUP62	-299	618
NUP85	4178	7946
NUP88	-4777	10134
NUP93	5831	11067
NUP98	-3764	7940
NUS1	-6395	13362
OBSL1	2391	4622
ODAM	7310	14256
OGT	6452	12301
OS9	-6986	14320
OTOA	87	171
OTUB1	-293	600
OTUB2	5916	11254
OTUD3	-2342	4849
OTUD5	-5944	12487
OTUD7A	589	1152
OTUD7B	-1911	3920
OTULIN	-2499	5175
OXA1L	2372	4586
P2RY2	-4163	8802
P4HB	-6884	14170
PABPC1	-3543	7490
PAF1	1828	3589
PAPPA	1432	2849
PARK7	-2508	5199
PARP1	2974	5715
PARS2	7123	13767
PAX6	-478	967
PCGF2	-5881	12369
PCMT1	-5697	11983
PCNA	6523	12452
PCSK9	7381	14502
PDCL	-1005	2055
PDIA3	-7086	14454
PDIA6	-7106	14482
PEX10	2668	5162
PEX12	4742	8996
PEX13	-721	1454
PEX14	-3636	7694
PEX2	4569	8675
PEX5	-346	707
PFDN1	4605	8746
PFDN2	-3625	7675
PFDN4	2960	5694
PFDN5	-2781	5784
PFDN6	5123	9689
PGAP1	5952	11332
PGM3	-5395	11367
PHC1	-4280	9053
PHC2	3713	7072
PHC3	843	1660
PIAS1	-272	560
PIAS2	388	761
PIAS3	-1381	2775
PIAS4	-5022	10596
PIGA	-4278	9048
PIGB	4297	8147
PIGC	2130	4155
PIGF	4815	9133
PIGG	-6186	12950
PIGH	-1877	3848
PIGK	6215	11827
PIGL	5841	11096
PIGM	5248	9913
PIGN	-1322	2662
PIGO	2315	4481
PIGP	3397	6509
PIGQ	4551	8638
PIGS	-609	1243
PIGT	-1154	2351
PIGU	1074	2112
PIGV	4200	7983
PIGW	-5277	11146
PIGX	63	124
PIGY	948	1867
PIGZ	5536	10536
PLAUR	4485	8513
PLG	7380	14495
PML	1051	2057
PMM1	-2658	5521
PMM2	-5187	10956
PNPLA2	-5366	11306
POFUT2	-264	542
POLB	-4316	9130
POM121	-6353	13281
POM121C	-6045	12687
POMGNT1	3215	6187
POMGNT2	4488	8517
POMK	2475	4768
POMT1	-3914	8266
POMT2	-6788	14007
PPA1	-1553	3152
PPA2	2403	4640
PPARA	-6722	13906
PPARG	-3168	6636
PPARGC1A	-5869	12350
PPP6C	-5241	11074
PPP6R1	-6511	13558
PPP6R3	-623	1271
PREB	1446	2868
PRKCSH	-5934	12463
PRKDC	-2300	4777
PRMT3	5707	10843
PROC	6720	12863
PROS1	6053	11519
PROZ	6212	11823
PRSS23	655	1288
PSENEN	-2327	4828
PSMA1	-5730	12052
PSMA2	-5801	12203
PSMA3	-3078	6422
PSMA4	-4211	8902
PSMA5	-2715	5657
PSMA6	-126	261
PSMA7	-892	1820
PSMB1	1054	2062
PSMB10	423	838
PSMB2	1876	3678
PSMB3	-1915	3928
PSMB4	-1144	2330
PSMB5	-742	1484
PSMB6	-4888	10326
PSMB7	-4372	9253
PSMB9	5491	10430
PSMC1	-5564	11724
PSMC2	-2389	4948
PSMC3	-1509	3070
PSMC4	-4808	10196
PSMC5	-4091	8646
PSMC6	-4878	10307
PSMD1	-5351	11280
PSMD10	4933	9356
PSMD11	-432	879
PSMD12	4303	8163
PSMD13	-2577	5353
PSMD14	5974	11371
PSMD2	-6435	13423
PSMD3	-5535	11655
PSMD4	4567	8670
PSMD5	5116	9676
PSMD6	-5951	12502
PSMD7	4942	9371
PSMD8	-2928	6091
PSMD9	-4638	9853
PSME1	-2348	4861
PSME2	-5481	11555
PSME3	-3813	8052
PSME4	-6450	13450
PSMF1	-6663	13810
PTCD3	1514	2990
PTEN	-4721	10023
PTP4A2	-5085	10739
PTRH2	-5409	11393
PUM2	-5288	11167
QSOX1	-1250	2518
RAB10	1625	3205
RAB11A	4527	8597
RAB11B	-876	1793
RAB12	950	1872
RAB13	3724	7089
RAB14	3647	6952
RAB15	-3665	7753
RAB17	-7135	14521
RAB18	-372	760
RAB1A	-3307	6957
RAB1B	-3479	7340
RAB20	-6619	13727
RAB21	2694	5208
RAB22A	-6525	13585
RAB23	4722	8961
RAB24	4024	7638
RAB26	2740	5288
RAB27A	3011	5804
RAB29	1630	3213
RAB2A	-5379	11326
RAB2B	-1387	2784
RAB30	288	562
RAB31	-4876	10305
RAB32	-5287	11166
RAB33B	-2981	6213
RAB35	-5270	11131
RAB36	4950	9394
RAB37	6989	13426
RAB39B	-1774	3618
RAB3A	4309	8176
RAB3B	-1738	3544
RAB3D	1600	3155
RAB40B	4658	8839
RAB40C	-5019	10588
RAB42	4442	8434
RAB43	-6699	13874
RAB4A	-2148	4453
RAB4B	3174	6116
RAB5A	-5408	11392
RAB5B	2913	5611
RAB5C	-3129	6565
RAB6A	1296	2578
RAB6B	1396	2780
RAB7A	-5810	12220
RAB8A	-2247	4658
RAB8B	4676	8875
RAB9A	-6014	12633
RABGGTA	-4673	9926
RABGGTB	-5199	10986
RAD18	6045	11508
RAD21	601	1178
RAD23A	7141	13802
RAD23B	3141	6054
RAD52	6185	11769
RAE1	4394	8335
RANBP2	-4	9
RANGAP1	3458	6615
RARA	-6269	13109
RARS2	5085	9611
RBBP5	-101	204
RBBP7	5134	9712
RBX1	-3714	7850
RCE1	-1124	2289
RCN1	3434	6562
RECK	7128	13774
RELA	-2632	5468
RENBP	-5761	12130
RFT1	5083	9608
RFWD2	-2022	4150
RGS9	2861	5517
RHOA	-5294	11182
RHOT1	4106	7793
RING1	4067	7710
RIPK1	-2886	6000
RIPK2	-5779	12158
RNF103	-6135	12848
RNF123	-4681	9939
RNF128	-1375	2768
RNF135	126	247
RNF139	-3064	6382
RNF144A	4501	8547
RNF146	825	1622
RNF168	-3576	7562
RNF181	-4815	10206
RNF185	-6359	13291
RNF2	2454	4732
RNF20	5837	11085
RNF40	-5459	11493
RNF5	-6629	13745
RNF7	-611	1249
RORA	-5875	12360
RPA1	-5008	10563
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPN1	-7013	14350
RPN2	-6193	12964
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
RRAGA	2609	5038
RTF1	-1751	3574
RTN4RL2	5004	9479
RUVBL1	5317	10058
RWDD3	6644	12691
RXRA	-4073	8607
SAE1	1799	3527
SAFB	-6184	12947
SAR1B	-2973	6198
SARS2	-521	1066
SATB2	-2932	6101
SCFD1	485	960
SCMH1	6656	12722
SDC2	147	289
SEC11A	-3046	6345
SEC11C	-6991	14325
SEC13	-6812	14049
SEC16A	-5971	12546
SEC16B	6744	12908
SEC22A	3312	6374
SEC22B	859	1690
SEC22C	-1684	3433
SEC23A	-2717	5659
SEC23IP	390	767
SEC24A	-6839	14088
SEC24B	-5475	11541
SEC24C	-6236	13047
SEC24D	-7134	14520
SEC31A	-5766	12138
SEC61A1	-7030	14374
SEC61A2	-1397	2808
SEC61B	-6958	14278
SEC61G	-4052	8561
SEH1L	-4472	9474
SEL1L	-7124	14508
SELENOS	-7117	14498
SEM1	-3130	6566
SENP1	-886	1811
SENP2	-3731	7874
SENP5	-5170	10920
SENP8	6135	11684
SERPINA1	4014	7622
SERPINA10	4206	7992
SERPINC1	-6588	13683
SERPIND1	6689	12796
SFTPB	-720	1453
SHISA5	4853	9203
SHPRH	6150	11706
SIAH1	-3347	7045
SIAH2	-6666	13819
SIN3A	-5884	12373
SKIV2L	4599	8733
SKP1	-544	1117
SKP2	5946	11323
SLC17A5	-7072	14434
SLC30A5	-3771	7959
SLC30A6	4251	8074
SLC30A7	-6817	14058
SLC35A1	3906	7418
SLC35C1	-6667	13821
SMAD1	4977	9435
SMAD2	-4087	8639
SMAD3	-6145	12871
SMAD4	2742	5290
SMAD7	3117	6006
SMC1A	784	1560
SMC3	2546	4924
SMC5	-2095	4328
SMC6	2150	4184
SMURF2	-5253	11093
SNX3	-4858	10279
SOCS2	-1346	2710
SOCS3	7374	14476
SOCS5	-6643	13766
SOCS6	-5467	11523
SORL1	-3586	7576
SP100	-2455	5083
SP3	-4660	9908
SPCS1	2416	4672
SPCS2	-5930	12458
SPCS3	-6781	13996
SPHK1	-3142	6587
SPON2	-6404	13375
SPP1	-5872	12355
SPP2	1592	3138
SPSB1	1077	2118
SPSB2	-1306	2622
SPSB3	-4739	10054
SPTAN1	2385	4610
SPTBN1	-4901	10356
SPTBN2	3883	7379
SRD5A3	4758	9027
SRP14	-5938	12470
SRP19	-6363	13297
SRP54	-1969	4041
SRP68	-6420	13394
SRP72	-5526	11640
SRP9	5604	10650
SRPRA	-4802	10175
SRPRB	-6893	14181
SSR1	-6907	14205
SSR2	-6759	13968
SSR3	-6928	14235
SSR4	-7004	14338
ST3GAL1	-5905	12408
ST3GAL2	-4518	9594
ST3GAL3	5918	11257
ST3GAL4	-6801	14033
ST3GAL5	5090	9630
ST3GAL6	-3252	6829
ST6GAL1	-1828	3739
ST6GALNAC4	-6726	13912
ST6GALNAC6	-4820	10212
ST8SIA1	2289	4428
ST8SIA5	-1758	3583
STAG1	-3341	7037
STAG2	-2617	5443
STAM	5109	9665
STAM2	3080	5933
STAMBP	5873	11154
STAMBPL1	2213	4302
STAT3	4253	8078
STC2	-6224	13029
STS	-4430	9373
STT3A	-6796	14026
STX17	2586	4997
STX1A	-2377	4922
STX5	-5300	11191
SUDS3	-2287	4748
SUMF1	6175	11754
SUMF2	1101	2158
SUMO1	3308	6365
SUMO2	1568	3089
SUMO3	4906	9299
SUZ12	346	664
SVBP	-1922	3948
SYVN1	-7108	14485
TAB1	6687	12789
TADA2B	-5182	10948
TADA3	-1216	2462
TAF10	626	1223
TAF9B	6106	11625
TARS2	2575	4978
TBC1D20	-6203	12985
TBCA	3995	7588
TBCB	1809	3552
TBCC	2785	5369
TBCD	-3294	6931
TBCE	923	1805
TCF7L2	959	1893
TCP1	-4735	10050
TDG	-3113	6520
TECTA	2402	4639
TECTB	-6219	13015
TF	5850	11111
TFG	-5336	11250
TFPT	1213	2390
TGFA	-4511	9574
TGFB1	-6934	14241
TGFBI	-4782	10140
TGFBR1	-2620	5447
TGFBR2	-3644	7714
TGOLN2	-2105	4352
THBS1	5988	11408
THBS2	2512	4856
THRA	-2996	6251
THRB	-3951	8360
THSD1	-5333	11244
THSD4	-6356	13286
TIMP1	-6294	13158
TMED10	-6116	12817
TMED2	-7071	14433
TMED3	-4057	8567
TMED7	-6933	14240
TMED9	-6502	13545
TMEM115	-6764	13976
TMEM129	4918	9321
TMEM132A	2376	4597
TNFAIP3	4359	8284
TNIP1	-4433	9381
TNIP2	-1314	2640
TNKS	-4790	10153
TNKS2	-3213	6742
TOMM20	676	1324
TOMM70	-2797	5819
TOP1	-6472	13490
TOP2A	6875	13176
TOP2B	-3712	7845
TOPORS	-2753	5743
TP53	-2020	4144
TP53BP1	4788	9089
TPGS1	-5251	11091
TPGS2	5616	10668
TPR	565	1105
TPST1	-2126	4399
TPST2	-2873	5975
TRAF2	-577	1180
TRAF3	-356	729
TRAF6	1597	3150
TRAM1	-6997	14331
TRAPPC1	3089	5956
TRAPPC10	-6585	13677
TRAPPC2	3547	6775
TRAPPC2L	-4576	9709
TRAPPC3	-4032	8524
TRAPPC4	1781	3487
TRAPPC5	239	470
TRAPPC6A	7244	14069
TRAPPC6B	2584	4993
TRAPPC9	5033	9528
TRIM13	1883	3695
TRIM25	-5492	11574
TRIM27	-4835	10241
TRIM28	-3099	6471
TRIM4	-4229	8937
TRMT112	-3869	8181
TRRAP	-3581	7571
TSFM	-1098	2236
TSPAN14	-4626	9825
TSPAN15	4238	8046
TSPAN33	4207	7993
TSPAN5	-2154	4464
TTF1	5165	9758
TTL	-2640	5487
TTLL1	6723	12868
TTLL11	-6233	13041
TTLL12	-556	1140
TTLL3	7102	13715
TTLL4	2011	3926
TTLL5	-713	1443
TTLL7	-3685	7789
TTLL9	-1023	2086
TTR	-3924	8283
TUBA1A	4706	8932
TUBA1B	7094	13681
TUBA1C	6761	12940
TUBA4A	682	1335
TUBA8	-1280	2575
TUBB1	2717	5236
TUBB2A	1290	2568
TUBB2B	4184	7952
TUBB3	436	858
TUBB4B	6758	12934
TUBB6	-1115	2268
TUBB8	4034	7651
TUFM	-3458	7286
TULP4	-4002	8471
TUSC3	-1219	2465
TXN	-3611	7626
UAP1	-898	1828
UBA1	516	1021
UBA2	-3913	8263
UBA3	-1275	2562
UBA52	-5068	10707
UBA6	-2266	4704
UBB	-4263	9013
UBC	779	1551
UBD	3463	6630
UBE2A	3752	7140
UBE2B	-2586	5375
UBE2C	7137	13793
UBE2D1	3523	6734
UBE2D2	-913	1857
UBE2D3	-3997	8449
UBE2E1	3733	7102
UBE2E3	-2654	5512
UBE2F	-5885	12374
UBE2G1	-5763	12134
UBE2G2	-718	1451
UBE2H	5369	10168
UBE2I	-1318	2653
UBE2J2	-6232	13040
UBE2K	383	750
UBE2L3	-3143	6589
UBE2L6	7272	14134
UBE2M	-4337	9174
UBE2N	1836	3604
UBE2Q2	2642	5107
UBE2R2	-386	790
UBE2S	-1872	3839
UBE2T	5710	10846
UBE2V2	3369	6467
UBE2W	-1973	4047
UBE2Z	-964	1959
UBXN1	-5450	11466
UBXN7	1120	2192
UCHL3	-5231	11055
UCHL5	443	875
UCN	5800	11013
UGGT1	-6954	14270
UGGT2	1425	2839
UHRF2	-2752	5740
UIMC1	-6627	13741
USO1	-3509	7413
USP10	1016	1999
USP11	2763	5328
USP12	-3488	7363
USP13	6054	11521
USP14	5232	9882
USP15	-4344	9193
USP16	-6545	13615
USP18	5875	11159
USP19	-2419	5014
USP2	-5430	11427
USP20	1248	2470
USP21	2804	5405
USP22	-5265	11124
USP24	-2786	5792
USP25	-325	676
USP28	-1668	3404
USP3	-3962	8383
USP30	6349	12091
USP33	1924	3761
USP34	-4441	9391
USP37	3800	7241
USP4	1449	2874
USP42	-5109	10780
USP47	-1849	3795
USP48	2408	4648
USP49	1405	2797
USP5	-2837	5894
USP7	134	258
USP8	-2820	5864
USP9X	-4318	9136
VAMP2	-5088	10744
VARS2	-1827	3738
VASH1	2462	4751
VASH2	5945	11320
VBP1	-3287	6910
VCAN	-5649	11899
VCP	-6720	13902
VCPIP1	-5042	10640
VCPKMT	4329	8222
VDAC1	-1027	2092
VDAC2	-2869	5966
VDAC3	-273	561
VGF	-6864	14140
VHL	-6491	13531
VNN1	5548	10554
VNN3	6337	12074
VWA1	2832	5457
WAC	-5965	12537
WARS2	4080	7734
WDR20	-3937	8319
WDR48	543	1063
WDR5	2561	4953
WDR61	452	889
WDTC1	-1303	2617
WFS1	-7096	14466
WRAP53	2169	4218
WRN	3032	5841
WSB1	-4879	10308
WSB2	-7029	14373
XPC	5353	10123
XPNPEP2	6043	11506
XRCC4	3376	6479
XRN2	-3427	7216
YARS2	-645	1313
YKT6	-4899	10349
YOD1	-6141	12859
YY1	-5214	11015
ZBED1	3448	6594
ZDHHC2	-1819	3717
ZNF131	-3603	7607
ZNF350	2186	4246
ZRANB1	-5895	12391

---

---

Axon guidance

Axon guidance

metric	value
setSize	424
pMANOVA	3.06e-15
p.adjustMANOVA	3.88e-13
s.dist	0.233
s.x	-0.232
s.abs	0.00935
p.x	2.94e-16
p.abs	0.742

Top 20 genes

Gene	x	abs
VASP	-7075	14437
ABLIM1	-7055	14411
RPL36AL	-6981	14313
ETF1	-6952	14268
RNPS1	-6938	14245
ARHGEF28	-6925	14232
SHC1	-6910	14209
MET	-6878	14159
RANBP9	-6871	14151
EPHA2	-6857	14124
ACTG1	-6841	14090
GSPT1	-6825	14070
ANK2	-6778	13993
SEMA6A	-6761	13971
RHOC	-6747	13943
SCN2A	-6712	13891
SIAH2	-6666	13819
PSMF1	-6663	13810
MYL12B	-6653	13785
WASL	-6543	13611

Click HERE to show all gene set members

All member genes

	x	abs
ABL1	2023	3944
ABL2	-3020	6296
ABLIM1	-7055	14411
ABLIM2	6389	12183
ABLIM3	2675	5174
ACTB	-5057	10683
ACTG1	-6841	14090
ACTR2	1435	2855
ACTR3	-5296	11186
ADAM10	-2671	5549
AGAP2	4399	8342
AGRN	-2369	4911
AKAP5	3035	5848
ALCAM	3171	6109
ANK1	-4656	9901
ANK2	-6778	13993
ANK3	303	591
AP2A1	-1902	3903
AP2A2	-3499	7391
AP2B1	2029	3955
AP2M1	-4603	9787
AP2S1	-2922	6073
APH1A	619	1209
APH1B	6168	11741
ARHGAP35	-6446	13445
ARHGAP39	-6303	13184
ARHGEF11	-5260	11110
ARHGEF12	-1086	2216
ARHGEF28	-6925	14232
ARHGEF7	-2913	6055
ARPC1A	3022	5822
ARPC1B	-4429	9372
ARPC2	-2209	4575
ARPC3	3797	7237
ARPC4	-6094	12778
ARPC5	-1511	3073
ARTN	973	1918
CACNA1D	-5676	11949
CACNA1H	-3915	8269
CACNB1	2967	5703
CACNB3	3735	7109
CACNB4	1983	3874
CAP1	-4085	8634
CAP2	-2694	5594
CASC3	-5986	12577
CD24	5327	10076
CDC42	-2172	4489
CDK5	-1352	2721
CDK5R1	-157	326
CFL1	-5737	12075
CLASP1	1561	3071
CLASP2	-4246	8977
CLTA	-6439	13432
CLTB	-6064	12719
CLTC	-6220	13017
CLTCL1	6404	12210
CNTN2	200	389
CNTNAP1	7239	14053
COL4A5	6694	12804
COL6A1	7322	14284
COL6A2	3222	6195
COL6A3	2085	4068
COL9A2	7348	14389
COL9A3	7151	13817
CREB1	474	935
CSNK2A1	-5040	10637
CSNK2A2	-4546	9641
CSNK2B	4415	8368
CUL2	359	703
DAG1	-2174	4498
DLG1	-3865	8171
DLG3	5168	9763
DLG4	5108	9664
DNM1	6505	12417
DNM2	-6535	13597
DOCK1	3540	6760
DOK1	4072	7718
DOK4	-2697	5609
DOK6	-2987	6228
DPYSL2	-6519	13578
DPYSL4	1531	3019
DSCAML1	-2830	5885
EFNA1	-5830	12263
EFNA2	1735	3403
EFNA3	-1228	2484
EFNA4	3658	6973
EFNB1	3480	6658
EFNB2	-3470	7322
EFNB3	3419	6539
EGFR	-5383	11344
EIF4A3	1154	2270
EIF4G1	-5901	12400
ELOB	-3004	6272
ELOC	645	1265
ENAH	-3139	6582
EPHA1	4960	9410
EPHA10	1725	3385
EPHA2	-6857	14124
EPHB1	-5141	10858
EPHB4	-4379	9264
ERBB2	5534	10533
ETF1	-6952	14268
EVL	2467	4757
EZR	-4464	9453
FARP2	3688	7020
FAU	-4990	10520
FES	5506	10476
FGFR1	-6191	12960
FLRT3	7184	13907
FRS2	-3790	8007
FYN	1937	3783
GAB1	1575	3105
GAB2	-4127	8722
GDNF	-3969	8396
GFRA3	4393	8334
GIT1	-5582	11767
GPC1	5178	9776
GRB10	-5504	11598
GRB2	-3047	6346
GRB7	-4006	8477
GRIN1	-442	902
GRIN2B	1330	2648
GSK3B	-5101	10767
GSPT1	-6825	14070
HOXA2	2735	5280
HRAS	-5543	11673
HSP90AA1	-1030	2096
HSP90AB1	-4426	9363
HSPA8	-4654	9895
IRS2	-5461	11497
ITGA1	5152	9740
ITGA10	-6466	13478
ITGA2	-6205	12988
ITGA2B	-688	1391
ITGA5	587	1149
ITGAV	-4312	9120
ITGB1	-4145	8760
ITSN1	159	311
KALRN	-408	828
KIF4A	6056	11524
KRAS	-2044	4210
L1CAM	-904	1841
LAMA1	1285	2553
LAMB1	3783	7198
LAMC1	-1300	2611
LDB1	1882	3689
LIMK1	1565	3082
LIMK2	6394	12193
LYN	-3038	6328
LYPLA2	-4095	8653
MAGOH	-969	1976
MAGOHB	5814	11039
MAP2K1	-4120	8704
MAP2K2	-6087	12766
MAPK1	-5066	10705
MAPK11	251	492
MAPK12	-5538	11663
MAPK13	-1875	3846
MAPK14	2269	4391
MAPK3	6640	12684
MAPK7	-4382	9270
MAPK8	-700	1418
MET	-6878	14159
MMP2	-4677	9932
MSI1	4326	8215
MYH10	2558	4942
MYH11	1015	1998
MYH14	5492	10431
MYH9	-4726	10036
MYL12A	-3398	7159
MYL12B	-6653	13785
MYL6	-6380	13325
MYL9	2704	5218
MYO10	-5290	11171
MYO9B	-5920	12432
NCBP1	-2151	4458
NCBP2	6823	13081
NCK1	1525	3010
NCK2	-3916	8271
NCSTN	-554	1137
NEO1	4016	7629
NGEF	7064	13605
NRAS	2310	4465
NRCAM	-3815	8057
NRP1	1353	2695
NRP2	-5313	11212
NRTN	3870	7357
NTN4	-1999	4099
NUMB	-5224	11036
PABPC1	-3543	7490
PAK1	1031	2021
PAK2	-4957	10458
PAK4	-5359	11295
PDLIM7	-2636	5473
PFN1	-6285	13146
PFN2	6877	13179
PIK3CA	-2813	5849
PIK3CB	-2588	5379
PIK3CD	-4759	10102
PIK3R1	-4376	9259
PIK3R2	-1355	2728
PIK3R3	-2279	4734
PIP5K1C	-3229	6778
PITPNA	-5591	11779
PLCG1	2511	4855
PLXNA1	-1050	2146
PLXNA2	-3814	8056
PLXNA3	-6318	13213
PLXNB1	-1046	2132
PLXNB3	-3778	7967
PLXNC1	4319	8196
PLXND1	-5686	11963
PPP3CB	-4060	8574
PRKACA	1736	3407
PRKACB	-1429	2885
PRKAR2A	-860	1753
PRKCA	2439	4709
PRNP	-6115	12816
PSEN1	-4938	10427
PSEN2	-2559	5310
PSENEN	-2327	4828
PSMA1	-5730	12052
PSMA2	-5801	12203
PSMA3	-3078	6422
PSMA4	-4211	8902
PSMA5	-2715	5657
PSMA6	-126	261
PSMA7	-892	1820
PSMB1	1054	2062
PSMB10	423	838
PSMB2	1876	3678
PSMB3	-1915	3928
PSMB4	-1144	2330
PSMB5	-742	1484
PSMB6	-4888	10326
PSMB7	-4372	9253
PSMB9	5491	10430
PSMC1	-5564	11724
PSMC2	-2389	4948
PSMC3	-1509	3070
PSMC4	-4808	10196
PSMC5	-4091	8646
PSMC6	-4878	10307
PSMD1	-5351	11280
PSMD10	4933	9356
PSMD11	-432	879
PSMD12	4303	8163
PSMD13	-2577	5353
PSMD14	5974	11371
PSMD2	-6435	13423
PSMD3	-5535	11655
PSMD4	4567	8670
PSMD5	5116	9676
PSMD6	-5951	12502
PSMD7	4942	9371
PSMD8	-2928	6091
PSMD9	-4638	9853
PSME1	-2348	4861
PSME2	-5481	11555
PSME3	-3813	8052
PSME4	-6450	13450
PSMF1	-6663	13810
PSPN	-5177	10939
PTK2	-4346	9198
PTPN11	-867	1770
PTPRA	815	1606
RAC1	44	95
RANBP9	-6871	14151
RAP1GAP	-4998	10531
RASA1	2559	4950
RBM8A	-1583	3215
RBX1	-3714	7850
RDX	1011	1989
RELN	-662	1347
RGMA	3210	6178
RGMB	1321	2630
RHOA	-5294	11182
RHOB	6064	11537
RHOC	-6747	13943
RND1	-1410	2828
RNPS1	-6938	14245
ROBO1	-5577	11752
ROBO3	4691	8903
ROCK1	-3594	7591
ROCK2	-2772	5775
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS6KA1	-3857	8159
RPS6KA2	-1149	2339
RPS6KA3	-3030	6316
RPS6KA4	731	1447
RPS6KA5	3086	5949
RPS6KA6	3918	7442
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
RRAS	-1578	3199
SCN11A	-295	607
SCN1A	7327	14299
SCN1B	2398	4633
SCN2A	-6712	13891
SCN3B	2499	4826
SCN8A	249	488
SCN9A	3533	6751
SDC2	147	289
SDCBP	-1822	3724
SEM1	-3130	6566
SEMA3A	4001	7600
SEMA4D	6479	12347
SEMA6A	-6761	13971
SEMA7A	-3299	6944
SH3KBP1	-917	1864
SHANK3	935	1838
SHC1	-6910	14209
SHC3	-3782	7979
SHTN1	547	1074
SIAH1	-3347	7045
SIAH2	-6666	13819
SLIT1	886	1741
SOS1	-950	1928
SOS2	-5417	11402
SPTAN1	2385	4610
SPTBN1	-4901	10356
SPTBN2	3883	7379
SRC	3962	7516
SRGAP1	-1796	3662
SRGAP2	-1779	3627
SRGAP3	6775	12970
TIAM1	4452	8451
TLN1	-6146	12872
TRIO	-5341	11264
TRPC1	3602	6877
UBA52	-5068	10707
UBB	-4263	9013
UBC	779	1551
UNC5B	-6252	13071
UPF2	-3830	8093
UPF3A	-6189	12957
UPF3B	2326	4503
USP33	1924	3761
VASP	-7075	14437
VAV2	2817	5425
VAV3	-4642	9861
VLDLR	3001	5770
WASL	-6543	13611
YES1	-1340	2690
ZSWIM8	-5267	11127

---

---

Immune System

Immune System

metric	value
setSize	1374
pMANOVA	3.1e-15
p.adjustMANOVA	3.88e-13
s.dist	0.136
s.x	-0.106
s.abs	0.0855
p.x	8.91e-11
p.abs	1.75e-07

Top 20 genes

Gene	x	abs
HSPA5	-7144	14531
CALR	-7142	14529
SEC24D	-7134	14520
DNAJC3	-7131	14516
HSP90B1	-7129	14514
CANX	-7092	14462
PDIA3	-7086	14454
VASP	-7075	14437
PLPP5	-7074	14436
KLHL21	-7069	14429
UBE2J1	-7068	14428
ATP6V0B	-7064	14422
MAP3K8	-7060	14418
NCR3LG1	-7048	14403
MAGT1	-7045	14398
CNN2	-7036	14383
SEC61A1	-7030	14374
ERP44	-7023	14364
SQSTM1	-7010	14347
EIF4A1	-6995	14329

Click HERE to show all gene set members

All member genes

	x	abs
A1BG	7060	13591
AAAS	2965	5701
AAMP	-5076	10725
ABCE1	-819	1665
ABI1	-4478	9492
ABI2	-1197	2431
ABL1	2023	3944
ABL2	-3020	6296
ACAA1	3886	7384
ACLY	4562	8659
ACTB	-5057	10683
ACTG1	-6841	14090
ACTR10	5570	10590
ACTR1A	-5162	10903
ACTR1B	5765	10947
ACTR2	1435	2855
ACTR3	-5296	11186
ADAM10	-2671	5549
ADAM17	-5836	12276
ADAM8	-1193	2424
ADAR	-3971	8398
ADGRE5	-313	651
ADGRG3	1417	2825
AGA	6147	11701
AGER	-2057	4235
AGL	2176	4233
AGPAT2	4769	9047
AHCYL1	4874	9245
AHSG	25	62
AIP	-4270	9029
AKT1	-2958	6160
AKT2	-1946	3993
ALAD	6318	12045
ALDH3B1	6860	13143
ALDOA	-6463	13474
ALDOC	5970	11365
ALPK1	5041	9538
AMPD3	-829	1688
ANAPC1	1998	3900
ANAPC10	6071	11551
ANAPC11	-1544	3134
ANAPC13	-1975	4052
ANAPC2	-1639	3349
ANAPC4	305	595
ANAPC5	3942	7485
ANAPC7	6249	11895
ANO6	-5826	12256
ANPEP	4690	8901
ANXA2	6155	11716
AP1B1	940	1849
AP1G1	-1916	3931
AP1M1	2926	5637
AP1M2	914	1788
AP1S1	5804	11022
AP1S2	-4204	8889
AP1S3	-739	1480
AP2A1	-1902	3903
AP2A2	-3499	7391
AP2B1	2029	3955
AP2M1	-4603	9787
AP2S1	-2922	6073
APAF1	1277	2532
APEH	4698	8922
APOB	-2964	6172
APP	-6492	13532
APRT	3389	6499
AREL1	-303	629
ARF1	-6021	12642
ARG1	-4179	8835
ARHGAP9	-2170	4486
ARIH1	-1512	3075
ARIH2	-6355	13284
ARL8A	-5922	12434
ARMC8	2401	4638
ARPC1A	3022	5822
ARPC1B	-4429	9372
ARPC2	-2209	4575
ARPC3	3797	7237
ARPC4	-6094	12778
ARPC5	-1511	3073
ARSA	2878	5552
ARSB	-6939	14246
ASAH1	-6648	13777
ASB1	-4171	8818
ASB13	6386	12175
ASB18	-601	1231
ASB2	-6960	14280
ASB3	3026	5827
ASB4	-3822	8067
ASB6	-5243	11077
ASB7	-3889	8217
ASB8	-1103	2243
ASB9	5150	9735
ATAD3B	-6334	13239
ATF1	-4925	10407
ATF2	-6175	12933
ATG12	-3333	7022
ATG5	2931	5644
ATG7	5453	10354
ATOX1	3659	6974
ATP11A	1486	2935
ATP11B	-2420	5015
ATP6AP2	-1245	2508
ATP6V0A1	-6979	14310
ATP6V0A2	-6880	14162
ATP6V0B	-7064	14422
ATP6V0C	-6086	12764
ATP6V0D1	-6908	14206
ATP6V0D2	747	1494
ATP6V0E1	-6622	13731
ATP6V0E2	5683	10798
ATP6V1A	-3777	7965
ATP6V1B1	4549	8635
ATP6V1B2	-5574	11744
ATP6V1C1	-4946	10444
ATP6V1C2	-5929	12453
ATP6V1D	-6922	14228
ATP6V1E1	-6271	13114
ATP6V1E2	-534	1090
ATP6V1F	-868	1771
ATP6V1G1	-5352	11283
ATP6V1G2	690	1360
ATP6V1H	-4423	9358
ATP7A	2111	4123
ATP8A1	5995	11425
B2M	-2523	5242
B4GALT1	-262	540
BAIAP2	-637	1295
BATF	-4520	9599
BCL10	-4471	9472
BCL2	1925	3762
BCL2L1	-6349	13271
BCL2L11	-3834	8099
BCL6	-4296	9080
BIRC2	-499	1007
BIRC3	3477	6654
BIRC5	5174	9771
BLMH	5642	10712
BOLA2	-1094	2230
BPIFB1	6516	12440
BPIFB2	-4967	10473
BPIFB6	-5923	12439
BRI3	-6843	14094
BRK1	-5431	11428
BRWD1	-1263	2546
BST1	713	1408
BST2	2868	5531
BTBD1	37	81
BTN2A1	-6754	13956
BTN2A2	6418	12236
BTN3A1	7132	13787
BTN3A2	7149	13815
BTN3A3	6893	13210
BTNL9	-1735	3539
BTRC	1386	2757
C1R	7201	13954
C1S	7360	14430
C2	4264	8098
C3	7357	14417
C4A	7346	14381
C4B	7286	14173
C4BPA	5221	9865
C4BPB	-6787	14006
C5	7218	14003
C5AR1	6719	12862
C5AR2	3489	6671
C6	6620	12636
C6orf120	6141	11690
C7	4745	9004
C8A	7235	14042
C8B	7343	14372
C8G	-2213	4585
CAB39	-4956	10457
CALM1	-655	1340
CALR	-7142	14529
CAMK2A	4566	8669
CAMK2D	1711	3358
CAMK2G	2145	4176
CAND1	-1658	3381
CANT1	-2398	4969
CANX	-7092	14462
CAP1	-4085	8634
CAPN1	-5850	12305
CAPZA1	-4855	10272
CAPZA2	-1549	3143
CAPZB	-1169	2376
CARD9	2322	4496
CASP1	6109	11631
CASP10	-5555	11704
CASP2	4204	7990
CASP3	-5257	11107
CASP4	-184	379
CASP8	3157	6085
CASP9	-5247	11084
CAT	5018	9504
CBL	-5708	12008
CBLB	-2897	6025
CCL20	-6885	14171
CCL22	584	1142
CCND1	-137	277
CCNF	1291	2569
CCR6	-6932	14239
CCT2	-5926	12444
CCT8	-5605	11813
CD101	-3638	7697
CD14	6998	13442
CD19	-472	954
CD22	-6256	13079
CD226	372	728
CD36	5264	9953
CD4	6074	11557
CD40	949	1869
CD46	5036	9531
CD47	6101	11617
CD55	-6517	13575
CD58	-5480	11554
CD59	-3245	6818
CD63	-6107	12800
CD68	6463	12316
CD74	1162	2282
CD79A	-929	1885
CD8A	4468	8470
CD99	-2817	5861
CDA	6735	12891
CDC16	1175	2309
CDC20	5650	10732
CDC23	6113	11639
CDC26	-197	402
CDC27	-1529	3103
CDC34	-5516	11619
CDC42	-2172	4489
CDH1	7296	14202
CDK13	-6415	13387
CDKN1A	-3580	7569
CDKN1B	-786	1590
CEACAM1	-6974	14302
CEBPD	6867	13165
CENPE	5538	10538
CEP290	5787	10987
CFB	7350	14394
CFD	5558	10570
CFI	6891	13206
CFL1	-5737	12075
CHUK	-3364	7086
CIITA	1176	2310
CISH	6003	11440
CKAP4	-3939	8327
CLCF1	-5429	11424
CLEC10A	-6451	13452
CLEC2D	6035	11496
CLEC7A	1881	3685
CLTA	-6439	13432
CLTC	-6220	13017
CLU	5647	10723
CMTM6	-259	535
CNN2	-7036	14383
CNPY3	-3981	8413
CNTF	-3706	7828
COLEC11	-5996	12595
COLEC12	522	1036
COMMD3	4983	9446
COMMD9	-3531	7455
COPB1	-4098	8664
COTL1	-877	1794
CPB2	4337	8234
CPN1	4039	7658
CPN2	-110	221
CPNE1	-3710	7836
CPNE3	3303	6354
CPPED1	2657	5138
CRACR2A	-75	155
CRCP	979	1930
CREB1	474	935
CREBBP	-3888	8214
CREG1	-47	87
CRISPLD2	-2075	4273
CRK	-5650	11901
CRKL	524	1039
CRLF1	3695	7035
CSF1	-6711	13888
CSF2RA	43	94
CSF3R	7351	14395
CSK	-4113	8692
CSNK2B	4415	8368
CST3	3732	7101
CSTB	776	1547
CTF1	4240	8054
CTNNB1	3272	6288
CTSA	-6288	13149
CTSB	-5204	10996
CTSC	-4446	9398
CTSD	2812	5416
CTSE	125	246
CTSH	5655	10743
CTSK	-4821	10213
CTSL	-6951	14263
CTSS	1499	2960
CTSV	2161	4202
CUL1	-4129	8725
CUL2	359	703
CUL3	-3056	6363
CUL5	-1229	2485
CUL7	4377	8310
CXADR	72	136
CXCL8	3625	6916
CXCR2	1464	2899
CYB5R3	600	1177
CYBA	2202	4283
CYFIP1	1939	3785
CYFIP2	6224	11850
CYLD	-6066	12727
CYSTM1	-6768	13982
DBNL	3382	6490
DCTN1	-1635	3338
DCTN2	-3957	8375
DCTN3	1457	2887
DCTN4	-1937	3979
DCTN5	-3634	7690
DCTN6	-318	666
DDOST	-6429	13410
DDX3X	-6449	13448
DDX41	-5919	12428
DDX58	-927	1883
DEGS1	-6054	12708
DERA	5319	10063
DET1	6311	12028
DGAT1	111	222
DHX36	-566	1159
DHX58	6062	11535
DHX9	-4112	8688
DIAPH1	-5806	12211
DNAJC13	-677	1370
DNAJC3	-7131	14516
DNAJC5	-6522	13582
DNASE1L1	6262	11920
DNM1	6505	12417
DNM2	-6535	13597
DOCK1	3540	6760
DOK3	-5877	12363
DPP7	4601	8739
DSN1	6916	13258
DSP	-4746	10069
DTX3L	5458	10364
DTX4	3048	5869
DUSP3	-6541	13608
DUSP4	-5977	12556
DUSP6	-3376	7113
DUSP7	-3870	8185
DYNC1H1	-3614	7639
DYNC1I2	-2780	5783
DYNC1LI1	-2519	5237
DYNC1LI2	-3897	8235
DYNLL1	2509	4853
DYNLL2	6044	11507
DYNLT1	3809	7253
DZIP3	6813	13056
EBI3	5791	10994
ECSIT	-5840	12282
EDA	-1292	2594
EDA2R	-3214	6745
EEA1	-2764	5759
EEF1A1	-4138	8740
EEF2	-5049	10659
EGR1	-1475	2989
EIF2AK2	2886	5562
EIF4A1	-6995	14329
EIF4A2	5593	10631
EIF4A3	1154	2270
EIF4E	2473	4766
EIF4E2	-4465	9454
EIF4E3	2306	4457
EIF4G1	-5901	12400
EIF4G2	-6418	13391
EIF4G3	-5852	12310
ELK1	-5733	12060
ELMO1	-2779	5782
ELMO2	942	1854
ELOB	-3004	6272
ELOC	645	1265
ENAH	-3139	6582
EP300	-6470	13485
EPPIN	4893	9281
ERAP1	-1151	2345
ERAP2	4482	8507
ERP44	-7023	14364
EVL	2467	4757
F2	635	1246
FABP5	4021	7635
FADD	1889	3704
FAF2	-4640	9859
FBXL12	-1137	2320
FBXL13	-870	1783
FBXL14	-2614	5439
FBXL15	612	1200
FBXL16	7269	14129
FBXL18	-1507	3067
FBXL19	-2110	4369
FBXL20	-3941	8336
FBXL22	3108	5990
FBXL3	-2027	4168
FBXL4	4801	9111
FBXL5	5669	10775
FBXL8	2924	5631
FBXO10	18	43
FBXO11	-3853	8152
FBXO15	3559	6797
FBXO17	5986	11405
FBXO2	-78	158
FBXO21	4978	9436
FBXO22	4762	9038
FBXO27	3623	6911
FBXO30	137	270
FBXO31	-5485	11563
FBXO32	-5299	11189
FBXO4	4180	7948
FBXO41	6136	11685
FBXO44	-4694	9964
FBXO6	3932	7468
FBXO7	947	1865
FBXO9	-1843	3776
FBXW10	-2540	5268
FBXW11	-3784	7986
FBXW2	-294	602
FBXW4	6039	11502
FBXW5	-5945	12489
FBXW7	-2564	5325
FBXW8	3716	7078
FBXW9	890	1747
FCER1G	380	746
FGA	7336	14346
FGB	7226	14018
FGG	6697	12809
FKBP1A	-5189	10960
FLNA	-6833	14081
FLNB	2867	5530
FLT3LG	6000	11436
FN1	-3115	6525
FOS	-5174	10931
FOXO1	5418	10275
FOXO3	2282	4415
FRK	602	1179
FSCN1	2591	5006
FTH1	-5419	11406
FTL	-6697	13872
FUCA1	2696	5210
FUCA2	-6538	13600
FYN	1937	3783
FZR1	201	397
GAA	4697	8919
GAB2	-4127	8722
GALNS	-6314	13205
GAN	-3641	7702
GBP1	3503	6692
GBP2	-4577	9711
GBP4	1334	2652
GBP5	2542	4914
GCA	7258	14108
GDI2	-2026	4162
GGH	-6936	14243
GHDC	-827	1682
GHR	733	1455
GLA	-5640	11875
GLB1	1557	3064
GLIPR1	-4691	9959
GLMN	1839	3608
GM2A	5280	9989
GMFG	-220	450
GNS	-6813	14052
GOLGA7	-3421	7208
GPI	-4904	10361
GRB10	-5504	11598
GRB2	-3047	6346
GRN	-2805	5836
GSDMD	5413	10266
GSN	1496	2952
GSTA2	5171	9767
GSTO1	2273	4401
GUSB	1260	2493
GYG1	-1167	2373
HACE1	6570	12533
HAVCR2	-1603	3267
HEBP2	-3167	6631
HECTD1	-5553	11699
HECTD2	1208	2378
HECTD3	-2034	4185
HERC1	-2688	5582
HERC2	-3739	7888
HERC3	3443	6583
HERC4	-1256	2535
HERC5	1855	3641
HERC6	5973	11369
HEXB	-6455	13459
HGSNAT	5921	11261
HIF1A	-4165	8807
HLA-A	5777	10971
HLA-B	2764	5329
HLA-C	5936	11297
HLA-H	4193	7975
HMGB1	5546	10552
HMOX1	4592	8715
HMOX2	-4742	10061
HNRNPA2B1	-6445	13444
HNRNPDL	-933	1890
HNRNPF	-6735	13925
HP	6732	12884
HRAS	-5543	11673
HSP90AA1	-1030	2096
HSP90AB1	-4426	9363
HSP90B1	-7129	14514
HSPA1A	1835	3603
HSPA5	-7144	14531
HSPA6	-3353	7061
HSPA8	-4654	9895
HSPA9	-6580	13667
HTN1	1687	3309
HTN3	2502	4834
HUWE1	-3769	7955
HVCN1	3884	7380
ICAM1	-1264	2548
ICAM2	6868	13167
ICAM3	-6441	13436
ICAM4	161	315
ICAM5	728	1440
ICOSLG	5061	9572
IDH1	-5470	11528
IFI27	-1017	2080
IFI30	-6187	12951
IFI35	6618	12631
IFI6	-4166	8808
IFIH1	6646	12693
IFIT1	6374	12148
IFIT3	5949	11329
IFIT5	6717	12858
IFITM1	-540	1106
IFITM2	3282	6308
IFITM3	-5819	12241
IFNAR1	4161	7910
IFNAR2	-2313	4798
IFNGR1	1624	3204
IFNGR2	997	1962
IFNLR1	-2031	4179
IGF2R	-6540	13604
IKBKB	-2931	6100
IKBKE	-787	1593
IKBKG	-5946	12493
IL10RB	5733	10890
IL11	-3967	8393
IL11RA	4693	8909
IL12A	4312	8182
IL12RB1	421	832
IL13RA1	5359	10143
IL15	586	1148
IL15RA	4756	9025
IL16	266	518
IL17RA	-186	382
IL17RB	-6937	14244
IL17RC	1440	2861
IL17RE	3847	7316
IL18	2102	4103
IL18BP	-4340	9182
IL1R1	6510	12430
IL1R2	892	1751
IL1RAP	5361	10146
IL1RL1	347	665
IL1RN	7124	13768
IL20RB	-3604	7608
IL21R	7359	14424
IL22RA1	-612	1251
IL23A	-1422	2869
IL27RA	122	242
IL32	5419	10276
IL34	6416	12233
IL4R	3348	6431
IL6R	-4943	10440
IL6ST	1965	3837
IL7	3739	7119
ILF2	-5258	11108
IMPDH1	-1807	3690
IMPDH2	4910	9308
INPP5D	3931	7467
INPPL1	-587	1197
IP6K2	-4148	8767
IQGAP1	-5663	11931
IQGAP2	-5323	11231
IRAK1	-2218	4593
IRAK2	-6713	13893
IRAK4	1591	3137
IRF1	5197	9820
IRF2	-335	690
IRF3	862	1694
IRF4	-3173	6647
IRF5	2827	5450
IRF9	-6092	12775
IRS1	3502	6691
IRS2	-5461	11497
ISG15	-5488	11568
ISG20	-5154	10884
IST1	-2001	4111
ITCH	-6089	12771
ITGAL	6325	12056
ITGAV	-4312	9120
ITGAX	1919	3756
ITGB1	-4145	8760
ITGB2	6494	12388
ITGB5	-5532	11649
ITK	-1112	2265
ITPR1	-4321	9146
ITPR2	2257	4366
ITPR3	-6088	12768
JAK1	-4963	10468
JAK2	-2719	5664
JAK3	7326	14295
JAML	1090	2138
JUN	-2934	6103
JUNB	-3526	7447
JUP	2314	4478
KBTBD6	6796	13016
KBTBD7	6772	12967
KBTBD8	2943	5662
KCMF1	-6393	13357
KCNAB2	675	1323
KCTD6	-178	368
KCTD7	-3550	7510
KEAP1	-6482	13510
KIF11	6577	12553
KIF15	6037	11499
KIF18A	5234	9884
KIF20A	5931	11285
KIF22	6933	13293
KIF23	6313	12032
KIF2A	-5815	12231
KIF2C	5981	11386
KIF3A	3299	6347
KIF3B	-6315	13207
KIF3C	1853	3639
KIF4A	6056	11524
KIF5A	-6634	13752
KIF5B	-5426	11419
KIF5C	2266	4382
KIFAP3	6573	12544
KLC1	4611	8755
KLC2	-3375	7112
KLC3	3105	5986
KLC4	3897	7401
KLHL11	-1223	2475
KLHL13	4291	8137
KLHL2	-3269	6866
KLHL20	3344	6424
KLHL21	-7069	14429
KLHL22	5084	9610
KLHL25	-215	441
KLHL42	-4874	10303
KLHL5	-991	2025
KLHL9	3712	7071
KLRD1	2155	4192
KLRG1	2270	4392
KLRK1	-2060	4247
KPNA1	-6701	13876
KPNA2	-4575	9708
KPNA3	-4357	9223
KPNA4	-1701	3478
KPNA5	258	506
KPNB1	-6379	13324
KRAS	-2044	4210
LAG3	-3610	7625
LAIR1	-3025	6304
LAMA5	6638	12680
LAMP1	-6982	14314
LAMP2	-6966	14291
LAMTOR1	-774	1557
LAMTOR2	-148	299
LAMTOR3	-2631	5467
LAT	-3697	7813
LAT2	670	1316
LBP	5684	10799
LCK	-6250	13069
LCN2	-4096	8658
LCP1	-901	1834
LEAP2	7329	14305
LGALS3	-6923	14229
LGALS9	-1496	3034
LGMN	1001	1966
LIF	-3587	7579
LIFR	-3759	7929
LIMK1	1565	3082
LMNB1	7101	13707
LMO7	-1246	2512
LNPEP	-3128	6564
LONRF1	5944	11318
LPCAT1	5166	9761
LRG1	6726	12875
LRR1	-494	1000
LRRC41	1992	3889
LRRFIP1	-5477	11545
LRSAM1	6259	11916
LTA4H	6248	11893
LTBR	-1719	3510
LTN1	-1814	3702
LY96	-1339	2689
LYN	-3038	6328
LYZ	3804	7247
MADCAM1	5372	10174
MAGT1	-7045	14398
MALT1	-6026	12658
MAN2B1	-600	1230
MANBA	3572	6817
MAOA	-3288	6912
MAP2K1	-4120	8704
MAP2K3	-3342	7038
MAP2K4	-4505	9558
MAP2K6	-2351	4868
MAP2K7	-4399	9311
MAP3K1	-6230	13035
MAP3K14	-2575	5349
MAP3K3	-5546	11679
MAP3K7	3767	7172
MAP3K8	-7060	14418
MAPK1	-5066	10705
MAPK10	2952	5681
MAPK11	251	492
MAPK12	-5538	11663
MAPK13	-1875	3846
MAPK14	2269	4391
MAPK3	6640	12684
MAPK7	-4382	9270
MAPK8	-700	1418
MAPK9	1760	3449
MAPKAP1	-5936	12466
MAPKAPK2	-6461	13468
MAPKAPK3	-5773	12147
MASP1	-6062	12716
MASP2	5751	10923
MAVS	1695	3323
MBL2	6911	13247
MCL1	-3681	7783
MEF2A	-3308	6959
MEFV	2468	4758
METTL7A	4368	8298
MEX3C	-5460	11495
MGRN1	-1188	2418
MGST1	2313	4472
MIB2	-4356	9222
MICA	1351	2693
MICB	-918	1866
MID1	2810	5413
MIF	-5176	10935
MKRN1	-5695	11981
MLEC	-6902	14193
MLST8	1875	3677
MMP2	-4677	9932
MMP3	-1680	3425
MOSPD2	1344	2673
MRE11	4100	7780
MT2A	-1121	2284
MTAP	4110	7801
MTOR	-3683	7785
MUC13	-1524	3097
MUC15	4828	9153
MUC20	-1019	2082
MUC5B	7378	14487
MVP	-5935	12465
MX1	5298	10017
MX2	-1456	2953
MYC	1892	3708
MYD88	5939	11305
MYH9	-4726	10036
MYLIP	-6047	12695
MYO10	-5290	11171
MYO1C	-1212	2457
MYO5A	-3500	7394
MYO9B	-5920	12432
NANOG	1164	2288
NAPRT	988	1945
NBEAL2	4086	7749
NCF2	-5438	11446
NCK1	1525	3010
NCKAP1	-2788	5794
NCKAP1L	-972	1980
NCKIPSD	5477	10395
NCR3LG1	-7048	14403
NCSTN	-554	1137
NDC1	-1490	3023
NDUFC2	-6804	14038
NECTIN2	-2239	4645
NEDD4	196	383
NEDD4L	7233	14037
NEU1	-6752	13953
NF2	-6559	13642
NFATC2	4720	8958
NFATC3	-6750	13947
NFKB1	-3507	7409
NFKB2	-1311	2634
NFKBIA	-6437	13427
NFKBIB	-6474	13495
NFKBIE	919	1799
NHLRC3	7191	13928
NIT2	5596	10636
NKIRAS1	150	298
NKIRAS2	-4598	9777
NLRC4	-3690	7799
NLRC5	4976	9432
NLRP1	136	269
NLRX1	6266	11926
NME2	-3974	8403
NOD1	5449	10348
NOS1	709	1403
NOS3	-4903	10359
NPC2	-6207	12991
NPDC1	5488	10426
NPEPPS	-1702	3480
NRAS	2310	4465
NUP107	6076	11561
NUP133	1362	2708
NUP153	2712	5230
NUP155	4796	9102
NUP160	-329	683
NUP188	-4991	10521
NUP205	-5275	11144
NUP210	6802	13025
NUP214	-1926	3957
NUP35	5982	11387
NUP37	7100	13706
NUP43	2808	5410
NUP50	-4733	10047
NUP54	3310	6371
NUP58	2380	4603
NUP62	-299	618
NUP85	4178	7946
NUP88	-4777	10134
NUP93	5831	11067
NUP98	-3764	7940
OAS1	-6953	14269
OAS3	-6048	12696
OPRD1	1233	2430
ORAI1	-1417	2851
ORAI2	-4848	10259
ORM1	-3973	8400
ORM2	-1240	2502
ORMDL3	5040	9537
OSBPL1A	-1032	2101
OSCAR	-4571	9699
OSMR	5392	10214
OSTF1	-4843	10254
OTUD5	-5944	12487
P2RX1	-6853	14116
P4HB	-6884	14170
PA2G4	-3141	6585
PAFAH1B2	-471	953
PAG1	2774	5350
PAK1	1031	2021
PAK2	-4957	10458
PANX1	-5636	11867
PCBP2	974	1919
PDAP1	-3657	7739
PDCD4	3127	6023
PDE12	1929	3769
PDIA3	-7086	14454
PDPK1	399	782
PDXK	-6100	12784
PDZD11	3385	6494
PECAM1	1098	2152
PELI1	-5222	11028
PELI2	-1870	3834
PELI3	5019	9505
PFKL	5437	10325
PGAM1	-6174	12932
PGM1	-4600	9783
PGM2	263	513
PGRMC1	-242	498
PIAS1	-272	560
PIK3AP1	-6957	14273
PIK3C3	-5220	11026
PIK3CA	-2813	5849
PIK3CB	-2588	5379
PIK3CD	-4759	10102
PIK3R1	-4376	9259
PIK3R2	-1355	2728
PIK3R3	-2279	4734
PIK3R4	1132	2219
PILRA	-1760	3588
PILRB	-136	276
PIM1	-4092	8647
PIN1	3074	5922
PITPNA	-5591	11779
PJA1	2653	5131
PJA2	-6376	13321
PKM	-5137	10849
PLA2G2A	7254	14102
PLA2G6	6084	11578
PLAC8	2524	4886
PLAU	-2962	6169
PLAUR	4485	8513
PLCG1	2511	4855
PLCG2	-3766	7942
PLD1	7290	14191
PLD2	4048	7673
PLD3	1239	2446
PLEKHO2	-4227	8935
PLPP5	-7074	14436
PML	1051	2057
PNP	-6810	14046
POLR1C	-4986	10515
POLR1D	-4516	9588
POLR2E	-4667	9916
POLR2F	-5283	11158
POLR2H	-3593	7590
POLR2K	5962	11350
POLR2L	-5471	11530
POLR3A	-2056	4231
POLR3B	-2273	4721
POLR3C	-1730	3531
POLR3D	4454	8453
POLR3E	-5626	11853
POLR3F	688	1355
POLR3G	1545	3049
POLR3GL	7315	14267
POLR3H	-2496	5168
POLR3K	3152	6076
POM121	-6353	13281
POM121C	-6045	12687
POU2F1	1266	2513
PPIA	-4443	9393
PPIE	1333	2651
PPL	-3149	6600
PPM1B	-5398	11375
PPP2CA	-5168	10917
PPP2CB	-4523	9606
PPP2R1A	-4744	10064
PPP2R1B	4614	8759
PPP2R5A	-5740	12088
PPP2R5B	-5131	10834
PPP2R5C	2743	5293
PPP2R5D	-2117	4385
PPP2R5E	283	554
PPP3CA	381	748
PPP3CB	-4060	8574
PPP3R1	-4176	8832
PRCP	-2276	4730
PRDX4	-6268	13105
PRDX6	-54	106
PRKACA	1736	3407
PRKACB	-1429	2885
PRKCD	-5638	11872
PRKCE	-5510	11606
PRKCSH	-5934	12463
PRKDC	-2300	4777
PRLR	-3529	7452
PROS1	6053	11519
PRR5	-2094	4323
PSAP	-5218	11023
PSEN1	-4938	10427
PSMA1	-5730	12052
PSMA2	-5801	12203
PSMA3	-3078	6422
PSMA4	-4211	8902
PSMA5	-2715	5657
PSMA6	-126	261
PSMA7	-892	1820
PSMB1	1054	2062
PSMB10	423	838
PSMB2	1876	3678
PSMB3	-1915	3928
PSMB4	-1144	2330
PSMB5	-742	1484
PSMB6	-4888	10326
PSMB7	-4372	9253
PSMB9	5491	10430
PSMC1	-5564	11724
PSMC2	-2389	4948
PSMC3	-1509	3070
PSMC4	-4808	10196
PSMC5	-4091	8646
PSMC6	-4878	10307
PSMD1	-5351	11280
PSMD10	4933	9356
PSMD11	-432	879
PSMD12	4303	8163
PSMD13	-2577	5353
PSMD14	5974	11371
PSMD2	-6435	13423
PSMD3	-5535	11655
PSMD4	4567	8670
PSMD5	5116	9676
PSMD6	-5951	12502
PSMD7	4942	9371
PSMD8	-2928	6091
PSMD9	-4638	9853
PSME1	-2348	4861
PSME2	-5481	11555
PSME3	-3813	8052
PSME4	-6450	13450
PSMF1	-6663	13810
PSTPIP1	5948	11328
PTAFR	4486	8514
PTEN	-4721	10023
PTGES2	3607	6882
PTK2	-4346	9198
PTK2B	6809	13043
PTPN1	3622	6909
PTPN11	-867	1770
PTPN12	-5326	11236
PTPN14	-4062	8577
PTPN18	6851	13128
PTPN2	-3809	8048
PTPN23	-5932	12460
PTPN4	-2238	4643
PTPN6	6557	12513
PTPN9	5324	10072
PTPRJ	-6103	12791
PTPRN2	1971	3851
PVR	-5786	12169
PYCARD	6900	13221
PYGB	-6693	13867
PYGL	4903	9295
QPCT	-2416	5009
QSOX1	-1250	2518
RAB10	1625	3205
RAB14	3647	6952
RAB18	-372	760
RAB24	4024	7638
RAB27A	3011	5804
RAB31	-4876	10305
RAB37	6989	13426
RAB3A	4309	8176
RAB3D	1600	3155
RAB4B	3174	6116
RAB5B	2913	5611
RAB5C	-3129	6565
RAB6A	1296	2578
RAB7A	-5810	12220
RAC1	44	95
RACGAP1	5789	10990
RAE1	4394	8335
RAF1	-5557	11708
RALA	-6548	13623
RANBP2	-4	9
RAP1A	309	604
RAP1B	3577	6830
RAP1GAP	-4998	10531
RAP1GAP2	3326	6395
RAP2B	-6173	12931
RAP2C	-1109	2257
RAPGEF1	-6586	13680
RAPGEF4	438	863
RASGRP3	-569	1164
RBBP6	-6244	13058
RBCK1	-2891	6012
RBSN	5208	9844
RBX1	-3714	7850
RCHY1	-2947	6131
REL	-160	330
RELA	-2632	5468
RELB	-469	951
RHOA	-5294	11182
RHOF	-2600	5403
RHOG	-2756	5747
RHOU	4579	8693
RICTOR	-2076	4274
RILP	-4675	9929
RIPK1	-2886	6000
RIPK2	-5779	12158
RLIM	-971	1979
RNASET2	-701	1419
RNF111	2443	4714
RNF114	-963	1958
RNF115	-2643	5494
RNF123	-4681	9939
RNF125	7321	14283
RNF126	-4225	8928
RNF130	-5910	12414
RNF135	126	247
RNF138	-1859	3815
RNF14	-3295	6933
RNF144B	6303	12014
RNF19A	-4816	10207
RNF19B	-4500	9545
RNF213	5584	10611
RNF216	4252	8077
RNF217	1448	2873
RNF220	999	1964
RNF25	622	1216
RNF34	-2647	5503
RNF4	-377	771
RNF41	6188	11780
RNF6	-5120	10809
RNF7	-611	1249
ROCK1	-3594	7591
RORA	-5875	12360
RORC	7056	13571
RPLP0	-4290	9067
RPS27A	-2773	5776
RPS6KA1	-3857	8159
RPS6KA2	-1149	2339
RPS6KA3	-3030	6316
RPS6KA5	3086	5949
S100A1	6858	13138
S100A11	-6865	14143
S100P	-2653	5511
SAMHD1	4346	8254
SAR1B	-2973	6198
SARM1	-3956	8374
SCAMP1	1817	3566
SDC1	2160	4201
SDCBP	-1822	3724
SEC13	-6812	14049
SEC22B	859	1690
SEC23A	-2717	5659
SEC24A	-6839	14088
SEC24B	-5475	11541
SEC24C	-6236	13047
SEC24D	-7134	14520
SEC31A	-5766	12138
SEC61A1	-7030	14374
SEC61A2	-1397	2808
SEC61B	-6958	14278
SEC61G	-4052	8561
SEH1L	-4472	9474
SEM1	-3130	6566
SERPINA1	4014	7622
SERPINA3	7328	14304
SERPINB1	2181	4239
SERPINB6	-2474	5125
SERPING1	7387	14532
SH2B1	-3615	7640
SH2B3	-4752	10091
SH3KBP1	-917	1864
SH3RF1	-6212	13005
SHC1	-6910	14209
SIAH1	-3347	7045
SIAH2	-6666	13819
SIGIRR	1500	2961
SIGLEC10	-594	1218
SIKE1	4383	8322
SIPA1	-4745	10068
SIRPA	-3538	7474
SIRPB1	1105	2169
SKP1	-544	1117
SKP2	5946	11323
SLA2	7214	13986
SLC11A1	3527	6739
SLC15A4	2407	4647
SLC27A2	829	1635
SLC2A3	-1535	3116
SLC2A5	3250	6243
SLC44A2	6879	13182
SLCO4C1	5675	10785
SMAD3	-6145	12871
SMARCA4	-3226	6773
SMURF1	-6229	13034
SMURF2	-5253	11093
SNAP23	-5681	11956
SNAP29	-703	1422
SNRPA1	-6983	14316
SOCS1	5053	9561
SOCS2	-1346	2710
SOCS3	7374	14476
SOCS5	-6643	13766
SOCS6	-5467	11523
SOD1	5779	10975
SOD2	7342	14367
SOS1	-950	1928
SOS2	-5417	11402
SP100	-2455	5083
SPSB1	1077	2118
SPSB2	-1306	2622
SPTAN1	2385	4610
SPTBN2	3883	7379
SQSTM1	-7010	14347
SRC	3962	7516
SRP14	-5938	12470
STAT1	-5668	11938
STAT2	76	146
STAT3	4253	8078
STAT5A	5288	10000
STAT5B	6572	12541
STAT6	-1541	3128
STBD1	-3361	7077
STIM1	-3329	7007
STK10	333	642
STK11IP	-2838	5898
STOM	-1523	3093
STUB1	3373	6475
STX1A	-2377	4922
STX3	-6959	14279
STX4	-491	995
STXBP2	740	1474
SUGT1	1662	3265
SUMO1	3308	6365
SURF4	-6593	13688
SVIP	2180	4238
SYNGR1	6711	12842
TAB1	6687	12789
TAB2	-3878	8201
TAB3	2566	4960
TALDO1	-5554	11703
TANK	-4621	9817
TAP1	-414	836
TAP2	-558	1143
TAPBP	-130	266
TAX1BP1	-6281	13141
TBC1D10C	5382	10190
TBK1	-5169	10919
TCIRG1	180	348
TCP1	-4735	10050
TGFB1	-6934	14241
THEM4	6080	11571
THOP1	-5882	12370
TICAM1	-1956	4022
TIFA	3587	6848
TIMP1	-6294	13158
TIMP2	-3938	8320
TIRAP	4446	8439
TKFC	7267	14126
TLR6	1131	2218
TLR9	-2371	4913
TMBIM1	-6493	13533
TMC6	-6114	12813
TMEM179B	-3567	7543
TMEM30A	-2956	6157
TMEM63A	3357	6449
TNFAIP3	4359	8284
TNFRSF11A	6300	12009
TNFRSF12A	-5405	11388
TNFRSF13C	4785	9085
TNFRSF14	2741	5289
TNFRSF1A	4807	9118
TNFRSF25	296	581
TNFRSF9	-640	1299
TNFSF12	4816	9134
TNFSF13	-1035	2105
TNFSF14	1985	3876
TNFSF15	-357	730
TNFSF4	-4966	10472
TNFSF9	763	1527
TNIP2	-1314	2640
TOLLIP	-6576	13662
TOM1	-4199	8877
TOMM70	-2797	5819
TP53	-2020	4144
TPP2	-6027	12660
TPR	565	1105
TRAF2	-577	1180
TRAF3	-356	729
TRAF6	1597	3150
TRAF7	-5369	11310
TRAIP	6925	13276
TRAPPC1	3089	5956
TRIB3	-6798	14029
TRIM11	-3250	6826
TRIM14	6269	11936
TRIM2	6197	11801
TRIM21	4105	7792
TRIM22	6415	12230
TRIM25	-5492	11574
TRIM26	-6126	12834
TRIM29	-412	834
TRIM3	5236	9887
TRIM32	5977	11376
TRIM35	-3032	6318
TRIM36	5698	10821
TRIM37	-3461	7290
TRIM38	-1131	2306
TRIM39	-3437	7228
TRIM4	-4229	8937
TRIM41	-3598	7599
TRIM45	6884	13192
TRIM46	-171	353
TRIM5	-6483	13511
TRIM50	3393	6504
TRIM56	6183	11765
TRIM62	-3535	7465
TRIM69	4557	8652
TRIM71	-1686	3441
TRIM8	-5512	11611
TRIP12	-4503	9551
TRPC1	3602	6877
TSPAN14	-4626	9825
TTR	-3924	8283
TUBB	5125	9694
TUBB4B	6758	12934
TXLNA	-3002	6268
TXN	-3611	7626
TXNDC5	-5385	11346
TXNIP	7384	14509
TYK2	5066	9579
UBA1	516	1021
UBA3	-1275	2562
UBA5	-3984	8421
UBA52	-5068	10707
UBA6	-2266	4704
UBA7	6211	11821
UBAC1	-312	648
UBB	-4263	9013
UBC	779	1551
UBE2A	3752	7140
UBE2B	-2586	5375
UBE2C	7137	13793
UBE2D1	3523	6734
UBE2D2	-913	1857
UBE2D3	-3997	8449
UBE2D4	3190	6143
UBE2E1	3733	7102
UBE2E2	2114	4127
UBE2E3	-2654	5512
UBE2F	-5885	12374
UBE2G1	-5763	12134
UBE2G2	-718	1451
UBE2H	5369	10168
UBE2J1	-7068	14428
UBE2J2	-6232	13040
UBE2K	383	750
UBE2L3	-3143	6589
UBE2L6	7272	14134
UBE2M	-4337	9174
UBE2N	1836	3604
UBE2O	-6331	13236
UBE2Q1	-6639	13760
UBE2Q2	2642	5107
UBE2R2	-386	790
UBE2S	-1872	3839
UBE2V1	-4655	9900
UBE2V2	3369	6467
UBE2W	-1973	4047
UBE2Z	-964	1959
UBE3A	-2547	5286
UBE3B	4451	8447
UBE3C	-6041	12679
UBE3D	-3465	7298
UBE4A	1433	2850
UBOX5	2442	4712
UBR1	2428	4691
UBR2	-1393	2800
UBR4	-6345	13266
UFL1	2652	5128
ULBP1	5560	10573
UNC13D	-1871	3835
UNC93B1	-517	1053
UNKL	5989	11412
USP18	5875	11159
USP41	1563	3076
VAMP2	-5088	10744
VAMP3	-698	1415
VAMP7	-2787	5793
VAMP8	-4969	10475
VAPA	-4898	10346
VASP	-7075	14437
VAT1	-4497	9540
VAV2	2817	5425
VAV3	-4642	9861
VCL	4407	8357
VCP	-6720	13902
VEGFA	-4456	9433
VHL	-6491	13531
VNN1	5548	10554
VRK3	-1278	2573
VTN	6910	13246
WASF1	-5712	12021
WASF2	-3366	7096
WASF3	2619	5070
WASL	-6543	13611
WIPF2	-2965	6174
WSB1	-4879	10308
WWP1	-779	1572
XAF1	5517	10493
XRCC5	-4164	8806
XRCC6	28	67
YES1	-1340	2690
YPEL5	-4173	8825
YWHAB	2082	4062
YWHAZ	-885	1810
ZAP70	-5027	10613
ZEB1	-533	1087
ZNRF1	590	1153
ZNRF2	-3150	6602

---

---

IRE1alpha activates chaperones

IRE1alpha activates chaperones

metric	value
setSize	50
pMANOVA	6.59e-15
p.adjustMANOVA	7.56e-13
s.dist	0.673
s.x	-0.489
s.abs	0.463
p.x	2.24e-09
p.abs	1.48e-08

Top 20 genes

Gene	x	abs
HSPA5	-7144	14531
DNAJB11	-7141	14528
HYOU1	-7140	14527
DNAJC3	-7131	14516
DNAJB9	-7125	14510
SYVN1	-7108	14485
PDIA6	-7106	14482
EDEM1	-7103	14479
WFS1	-7096	14466
GFPT1	-7051	14406
MYDGF	-6976	14306
SERP1	-6964	14288
WIPI1	-6942	14251
SHC1	-6910	14209
ATP6V0D1	-6908	14206
SSR1	-6907	14205
FKBP14	-6896	14184
SRPRB	-6893	14181
ERN1	-6872	14152
TSPYL2	-6784	14002

Click HERE to show all gene set members

All member genes

	x	abs
ACADVL	4157	7903
ADD1	-5966	12538
ARFGAP1	-1587	3224
ATP6V0D1	-6908	14206
CTDSP2	-4462	9444
CUL7	4377	8310
CXXC1	-6033	12670
DCTN1	-1635	3338
DDX11	6254	11907
DNAJB11	-7141	14528
DNAJB9	-7125	14510
DNAJC3	-7131	14516
EDEM1	-7103	14479
ERN1	-6872	14152
EXTL1	6941	13312
EXTL2	3353	6440
EXTL3	3575	6822
FKBP14	-6896	14184
GFPT1	-7051	14406
GOSR2	1238	2441
GSK3A	-3684	7787
HDGF	-6715	13896
HSPA5	-7144	14531
HYOU1	-7140	14527
KDELR3	976	1922
KLHDC3	-3802	8036
LMNA	-3717	7854
MYDGF	-6976	14306
PDIA5	579	1130
PDIA6	-7106	14482
PLA2G4B	4716	8953
PPP2R5B	-5131	10834
PREB	1446	2868
SEC31A	-5766	12138
SERP1	-6964	14288
SHC1	-6910	14209
SRPRA	-4802	10175
SRPRB	-6893	14181
SSR1	-6907	14205
SULT1A3	1040	2038
SYVN1	-7108	14485
TATDN2	-6467	13480
TLN1	-6146	12872
TPP1	-6407	13378
TSPYL2	-6784	14002
WFS1	-7096	14466
WIPI1	-6942	14251
XBP1	5937	11302
YIF1A	195	381
ZBTB17	-3194	6703

---

---

Innate Immune System

Innate Immune System

metric	value
setSize	740
pMANOVA	2.59e-14
p.adjustMANOVA	2.75e-12
s.dist	0.176
s.x	-0.125
s.abs	0.123
p.x	9.58e-09
p.abs	1.49e-08

Top 20 genes

Gene	x	abs
DNAJC3	-7131	14516
HSP90B1	-7129	14514
PLPP5	-7074	14436
ATP6V0B	-7064	14422
MAP3K8	-7060	14418
MAGT1	-7045	14398
CNN2	-7036	14383
ERP44	-7023	14364
LAMP1	-6982	14314
ATP6V0A1	-6979	14310
CEACAM1	-6974	14302
LAMP2	-6966	14291
CTSL	-6951	14263
ARSB	-6939	14246
GGH	-6936	14243
CCR6	-6932	14239
LGALS3	-6923	14229
ATP6V1D	-6922	14228
SHC1	-6910	14209
ATP6V0D1	-6908	14206

Click HERE to show all gene set members

All member genes

	x	abs
A1BG	7060	13591
AAMP	-5076	10725
ABI1	-4478	9492
ABI2	-1197	2431
ABL1	2023	3944
ACAA1	3886	7384
ACLY	4562	8659
ACTB	-5057	10683
ACTG1	-6841	14090
ACTR10	5570	10590
ACTR1B	5765	10947
ACTR2	1435	2855
ACTR3	-5296	11186
ADAM10	-2671	5549
ADAM8	-1193	2424
ADGRE5	-313	651
ADGRG3	1417	2825
AGA	6147	11701
AGER	-2057	4235
AGL	2176	4233
AGPAT2	4769	9047
AHCYL1	4874	9245
AHSG	25	62
ALAD	6318	12045
ALDH3B1	6860	13143
ALDOA	-6463	13474
ALDOC	5970	11365
ALPK1	5041	9538
AMPD3	-829	1688
ANO6	-5826	12256
ANPEP	4690	8901
ANXA2	6155	11716
AP1M1	2926	5637
AP2A2	-3499	7391
APAF1	1277	2532
APEH	4698	8922
APOB	-2964	6172
APP	-6492	13532
APRT	3389	6499
ARG1	-4179	8835
ARHGAP9	-2170	4486
ARL8A	-5922	12434
ARMC8	2401	4638
ARPC1A	3022	5822
ARPC1B	-4429	9372
ARPC2	-2209	4575
ARPC3	3797	7237
ARPC4	-6094	12778
ARPC5	-1511	3073
ARSA	2878	5552
ARSB	-6939	14246
ASAH1	-6648	13777
ATAD3B	-6334	13239
ATF1	-4925	10407
ATF2	-6175	12933
ATG12	-3333	7022
ATG5	2931	5644
ATG7	5453	10354
ATOX1	3659	6974
ATP11A	1486	2935
ATP11B	-2420	5015
ATP6AP2	-1245	2508
ATP6V0A1	-6979	14310
ATP6V0A2	-6880	14162
ATP6V0B	-7064	14422
ATP6V0C	-6086	12764
ATP6V0D1	-6908	14206
ATP6V0D2	747	1494
ATP6V0E1	-6622	13731
ATP6V0E2	5683	10798
ATP6V1A	-3777	7965
ATP6V1B1	4549	8635
ATP6V1B2	-5574	11744
ATP6V1C1	-4946	10444
ATP6V1C2	-5929	12453
ATP6V1D	-6922	14228
ATP6V1E1	-6271	13114
ATP6V1E2	-534	1090
ATP6V1F	-868	1771
ATP6V1G1	-5352	11283
ATP6V1G2	690	1360
ATP6V1H	-4423	9358
ATP7A	2111	4123
ATP8A1	5995	11425
B2M	-2523	5242
B4GALT1	-262	540
BAIAP2	-637	1295
BCL10	-4471	9472
BCL2	1925	3762
BCL2L1	-6349	13271
BIRC2	-499	1007
BIRC3	3477	6654
BPIFB1	6516	12440
BPIFB2	-4967	10473
BPIFB6	-5923	12439
BRI3	-6843	14094
BRK1	-5431	11428
BST1	713	1408
BST2	2868	5531
BTRC	1386	2757
C1R	7201	13954
C1S	7360	14430
C2	4264	8098
C3	7357	14417
C4A	7346	14381
C4B	7286	14173
C4BPA	5221	9865
C4BPB	-6787	14006
C5	7218	14003
C5AR1	6719	12862
C5AR2	3489	6671
C6	6620	12636
C6orf120	6141	11690
C7	4745	9004
C8A	7235	14042
C8B	7343	14372
C8G	-2213	4585
CAB39	-4956	10457
CALM1	-655	1340
CAND1	-1658	3381
CANT1	-2398	4969
CAP1	-4085	8634
CAPN1	-5850	12305
CAPZA1	-4855	10272
CAPZA2	-1549	3143
CARD9	2322	4496
CASP1	6109	11631
CASP10	-5555	11704
CASP2	4204	7990
CASP4	-184	379
CASP8	3157	6085
CASP9	-5247	11084
CAT	5018	9504
CCL22	584	1142
CCR6	-6932	14239
CCT2	-5926	12444
CCT8	-5605	11813
CD14	6998	13442
CD19	-472	954
CD36	5264	9953
CD4	6074	11557
CD46	5036	9531
CD47	6101	11617
CD55	-6517	13575
CD58	-5480	11554
CD59	-3245	6818
CD63	-6107	12800
CD68	6463	12316
CDA	6735	12891
CDC34	-5516	11619
CDC42	-2172	4489
CDK13	-6415	13387
CEACAM1	-6974	14302
CEP290	5787	10987
CFB	7350	14394
CFD	5558	10570
CFI	6891	13206
CFL1	-5737	12075
CHUK	-3364	7086
CKAP4	-3939	8327
CLEC10A	-6451	13452
CLEC7A	1881	3685
CLU	5647	10723
CMTM6	-259	535
CNN2	-7036	14383
CNPY3	-3981	8413
COLEC11	-5996	12595
COMMD3	4983	9446
COMMD9	-3531	7455
COPB1	-4098	8664
COTL1	-877	1794
CPB2	4337	8234
CPN1	4039	7658
CPN2	-110	221
CPNE1	-3710	7836
CPNE3	3303	6354
CPPED1	2657	5138
CRACR2A	-75	155
CRCP	979	1930
CREB1	474	935
CREBBP	-3888	8214
CREG1	-47	87
CRISPLD2	-2075	4273
CRK	-5650	11901
CSNK2B	4415	8368
CST3	3732	7101
CSTB	776	1547
CTNNB1	3272	6288
CTSA	-6288	13149
CTSB	-5204	10996
CTSC	-4446	9398
CTSD	2812	5416
CTSH	5655	10743
CTSK	-4821	10213
CTSL	-6951	14263
CTSS	1499	2960
CTSV	2161	4202
CUL1	-4129	8725
CXCR2	1464	2899
CYB5R3	600	1177
CYBA	2202	4283
CYFIP1	1939	3785
CYFIP2	6224	11850
CYLD	-6066	12727
CYSTM1	-6768	13982
DBNL	3382	6490
DDOST	-6429	13410
DDX3X	-6449	13448
DDX41	-5919	12428
DDX58	-927	1883
DEGS1	-6054	12708
DERA	5319	10063
DGAT1	111	222
DHX36	-566	1159
DHX58	6062	11535
DHX9	-4112	8688
DIAPH1	-5806	12211
DNAJC13	-677	1370
DNAJC3	-7131	14516
DNAJC5	-6522	13582
DNASE1L1	6262	11920
DNM1	6505	12417
DNM2	-6535	13597
DOCK1	3540	6760
DOK3	-5877	12363
DPP7	4601	8739
DSN1	6916	13258
DSP	-4746	10069
DTX4	3048	5869
DUSP3	-6541	13608
DUSP4	-5977	12556
DUSP6	-3376	7113
DUSP7	-3870	8185
DYNC1H1	-3614	7639
DYNC1LI1	-2519	5237
DYNLL1	2509	4853
DYNLT1	3809	7253
ECSIT	-5840	12282
EEA1	-2764	5759
EEF1A1	-4138	8740
EEF2	-5049	10659
ELK1	-5733	12060
ELMO1	-2779	5782
ELMO2	942	1854
EP300	-6470	13485
EPPIN	4893	9281
ERP44	-7023	14364
F2	635	1246
FABP5	4021	7635
FADD	1889	3704
FAF2	-4640	9859
FBXW11	-3784	7986
FCER1G	380	746
FGA	7336	14346
FGB	7226	14018
FGG	6697	12809
FOS	-5174	10931
FRK	602	1179
FTH1	-5419	11406
FTL	-6697	13872
FUCA1	2696	5210
FUCA2	-6538	13600
FYN	1937	3783
GAA	4697	8919
GAB2	-4127	8722
GALNS	-6314	13205
GCA	7258	14108
GDI2	-2026	4162
GGH	-6936	14243
GHDC	-827	1682
GLA	-5640	11875
GLB1	1557	3064
GLIPR1	-4691	9959
GM2A	5280	9989
GMFG	-220	450
GNS	-6813	14052
GOLGA7	-3421	7208
GPI	-4904	10361
GRB2	-3047	6346
GRN	-2805	5836
GSDMD	5413	10266
GSN	1496	2952
GUSB	1260	2493
GYG1	-1167	2373
HEBP2	-3167	6631
HERC5	1855	3641
HEXB	-6455	13459
HGSNAT	5921	11261
HLA-A	5777	10971
HLA-B	2764	5329
HLA-C	5936	11297
HLA-H	4193	7975
HMGB1	5546	10552
HMOX1	4592	8715
HMOX2	-4742	10061
HP	6732	12884
HRAS	-5543	11673
HSP90AA1	-1030	2096
HSP90AB1	-4426	9363
HSP90B1	-7129	14514
HSPA1A	1835	3603
HSPA6	-3353	7061
HSPA8	-4654	9895
HTN1	1687	3309
HTN3	2502	4834
HUWE1	-3769	7955
HVCN1	3884	7380
ICAM2	6868	13167
ICAM3	-6441	13436
IDH1	-5470	11528
IFIH1	6646	12693
IGF2R	-6540	13604
IKBKB	-2931	6100
IKBKE	-787	1593
IKBKG	-5946	12493
ILF2	-5258	11108
IMPDH1	-1807	3690
IMPDH2	4910	9308
IQGAP1	-5663	11931
IQGAP2	-5323	11231
IRAK1	-2218	4593
IRAK2	-6713	13893
IRAK4	1591	3137
IRF3	862	1694
ISG15	-5488	11568
IST1	-2001	4111
ITCH	-6089	12771
ITGAL	6325	12056
ITGAV	-4312	9120
ITGAX	1919	3756
ITGB2	6494	12388
ITK	-1112	2265
ITPR1	-4321	9146
ITPR2	2257	4366
ITPR3	-6088	12768
JUN	-2934	6103
JUP	2314	4478
KCMF1	-6393	13357
KCNAB2	675	1323
KLRD1	2155	4192
KLRK1	-2060	4247
KPNB1	-6379	13324
KRAS	-2044	4210
LAIR1	-3025	6304
LAMP1	-6982	14314
LAMP2	-6966	14291
LAMTOR1	-774	1557
LAMTOR2	-148	299
LAMTOR3	-2631	5467
LAT	-3697	7813
LAT2	670	1316
LBP	5684	10799
LCK	-6250	13069
LCN2	-4096	8658
LEAP2	7329	14305
LGALS3	-6923	14229
LGMN	1001	1966
LIMK1	1565	3082
LPCAT1	5166	9761
LRG1	6726	12875
LRRFIP1	-5477	11545
LTA4H	6248	11893
LY96	-1339	2689
LYN	-3038	6328
LYZ	3804	7247
MAGT1	-7045	14398
MALT1	-6026	12658
MAN2B1	-600	1230
MANBA	3572	6817
MAP2K1	-4120	8704
MAP2K3	-3342	7038
MAP2K4	-4505	9558
MAP2K6	-2351	4868
MAP2K7	-4399	9311
MAP3K1	-6230	13035
MAP3K14	-2575	5349
MAP3K7	3767	7172
MAP3K8	-7060	14418
MAPK1	-5066	10705
MAPK10	2952	5681
MAPK11	251	492
MAPK12	-5538	11663
MAPK13	-1875	3846
MAPK14	2269	4391
MAPK3	6640	12684
MAPK7	-4382	9270
MAPK8	-700	1418
MAPK9	1760	3449
MAPKAPK2	-6461	13468
MAPKAPK3	-5773	12147
MASP1	-6062	12716
MASP2	5751	10923
MAVS	1695	3323
MBL2	6911	13247
MEF2A	-3308	6959
MEFV	2468	4758
METTL7A	4368	8298
MGST1	2313	4472
MIF	-5176	10935
MLEC	-6902	14193
MOSPD2	1344	2673
MRE11	4100	7780
MUC13	-1524	3097
MUC15	4828	9153
MUC20	-1019	2082
MUC5B	7378	14487
MVP	-5935	12465
MYD88	5939	11305
MYH9	-4726	10036
MYO10	-5290	11171
MYO1C	-1212	2457
MYO5A	-3500	7394
MYO9B	-5920	12432
NAPRT	988	1945
NBEAL2	4086	7749
NCF2	-5438	11446
NCK1	1525	3010
NCKAP1	-2788	5794
NCKAP1L	-972	1980
NCKIPSD	5477	10395
NCSTN	-554	1137
NDUFC2	-6804	14038
NEU1	-6752	13953
NF2	-6559	13642
NFATC2	4720	8958
NFATC3	-6750	13947
NFKB1	-3507	7409
NFKB2	-1311	2634
NFKBIA	-6437	13427
NFKBIB	-6474	13495
NHLRC3	7191	13928
NIT2	5596	10636
NKIRAS1	150	298
NKIRAS2	-4598	9777
NLRC4	-3690	7799
NLRC5	4976	9432
NLRP1	136	269
NLRX1	6266	11926
NME2	-3974	8403
NOD1	5449	10348
NOS1	709	1403
NOS3	-4903	10359
NPC2	-6207	12991
NRAS	2310	4465
ORM1	-3973	8400
ORM2	-1240	2502
ORMDL3	5040	9537
OSCAR	-4571	9699
OSTF1	-4843	10254
OTUD5	-5944	12487
P2RX1	-6853	14116
PA2G4	-3141	6585
PAFAH1B2	-471	953
PAK1	1031	2021
PAK2	-4957	10458
PANX1	-5636	11867
PCBP2	974	1919
PDAP1	-3657	7739
PDPK1	399	782
PDXK	-6100	12784
PDZD11	3385	6494
PECAM1	1098	2152
PELI1	-5222	11028
PELI2	-1870	3834
PELI3	5019	9505
PFKL	5437	10325
PGAM1	-6174	12932
PGM1	-4600	9783
PGM2	263	513
PGRMC1	-242	498
PIK3C3	-5220	11026
PIK3CA	-2813	5849
PIK3CB	-2588	5379
PIK3R1	-4376	9259
PIK3R2	-1355	2728
PIK3R4	1132	2219
PIN1	3074	5922
PKM	-5137	10849
PLA2G2A	7254	14102
PLA2G6	6084	11578
PLAC8	2524	4886
PLAU	-2962	6169
PLAUR	4485	8513
PLCG1	2511	4855
PLCG2	-3766	7942
PLD1	7290	14191
PLD2	4048	7673
PLD3	1239	2446
PLEKHO2	-4227	8935
PLPP5	-7074	14436
PNP	-6810	14046
POLR1C	-4986	10515
POLR1D	-4516	9588
POLR2E	-4667	9916
POLR2F	-5283	11158
POLR2H	-3593	7590
POLR2K	5962	11350
POLR2L	-5471	11530
POLR3A	-2056	4231
POLR3B	-2273	4721
POLR3C	-1730	3531
POLR3D	4454	8453
POLR3E	-5626	11853
POLR3F	688	1355
POLR3G	1545	3049
POLR3GL	7315	14267
POLR3H	-2496	5168
POLR3K	3152	6076
PPIA	-4443	9393
PPIE	1333	2651
PPP2CA	-5168	10917
PPP2CB	-4523	9606
PPP2R1A	-4744	10064
PPP2R1B	4614	8759
PPP2R5D	-2117	4385
PPP3CA	381	748
PPP3CB	-4060	8574
PPP3R1	-4176	8832
PRCP	-2276	4730
PRDX4	-6268	13105
PRDX6	-54	106
PRKACA	1736	3407
PRKACB	-1429	2885
PRKCD	-5638	11872
PRKCE	-5510	11606
PRKCSH	-5934	12463
PRKDC	-2300	4777
PROS1	6053	11519
PSAP	-5218	11023
PSEN1	-4938	10427
PSMA1	-5730	12052
PSMA2	-5801	12203
PSMA3	-3078	6422
PSMA4	-4211	8902
PSMA5	-2715	5657
PSMA6	-126	261
PSMA7	-892	1820
PSMB1	1054	2062
PSMB10	423	838
PSMB2	1876	3678
PSMB3	-1915	3928
PSMB4	-1144	2330
PSMB5	-742	1484
PSMB6	-4888	10326
PSMB7	-4372	9253
PSMB9	5491	10430
PSMC1	-5564	11724
PSMC2	-2389	4948
PSMC3	-1509	3070
PSMC4	-4808	10196
PSMC5	-4091	8646
PSMC6	-4878	10307
PSMD1	-5351	11280
PSMD10	4933	9356
PSMD11	-432	879
PSMD12	4303	8163
PSMD13	-2577	5353
PSMD14	5974	11371
PSMD2	-6435	13423
PSMD3	-5535	11655
PSMD4	4567	8670
PSMD5	5116	9676
PSMD6	-5951	12502
PSMD7	4942	9371
PSMD8	-2928	6091
PSMD9	-4638	9853
PSME1	-2348	4861
PSME2	-5481	11555
PSME3	-3813	8052
PSME4	-6450	13450
PSMF1	-6663	13810
PSTPIP1	5948	11328
PTAFR	4486	8514
PTGES2	3607	6882
PTK2	-4346	9198
PTPN11	-867	1770
PTPN4	-2238	4643
PTPN6	6557	12513
PTPRJ	-6103	12791
PTPRN2	1971	3851
PYCARD	6900	13221
PYGB	-6693	13867
PYGL	4903	9295
QPCT	-2416	5009
QSOX1	-1250	2518
RAB10	1625	3205
RAB14	3647	6952
RAB18	-372	760
RAB24	4024	7638
RAB27A	3011	5804
RAB31	-4876	10305
RAB37	6989	13426
RAB3A	4309	8176
RAB3D	1600	3155
RAB4B	3174	6116
RAB5B	2913	5611
RAB5C	-3129	6565
RAB6A	1296	2578
RAB7A	-5810	12220
RAC1	44	95
RAF1	-5557	11708
RAP1A	309	604
RAP1B	3577	6830
RAP2B	-6173	12931
RAP2C	-1109	2257
RBSN	5208	9844
RELA	-2632	5468
RELB	-469	951
RHOA	-5294	11182
RHOF	-2600	5403
RHOG	-2756	5747
RIPK1	-2886	6000
RIPK2	-5779	12158
RNASET2	-701	1419
RNF125	7321	14283
RNF135	126	247
RNF216	4252	8077
ROCK1	-3594	7591
RPS27A	-2773	5776
RPS6KA1	-3857	8159
RPS6KA2	-1149	2339
RPS6KA3	-3030	6316
RPS6KA5	3086	5949
S100A1	6858	13138
S100A11	-6865	14143
S100P	-2653	5511
SARM1	-3956	8374
SCAMP1	1817	3566
SDCBP	-1822	3724
SEM1	-3130	6566
SERPINA1	4014	7622
SERPINA3	7328	14304
SERPINB1	2181	4239
SERPINB6	-2474	5125
SERPING1	7387	14532
SHC1	-6910	14209
SIGIRR	1500	2961
SIKE1	4383	8322
SIRPA	-3538	7474
SIRPB1	1105	2169
SKP1	-544	1117
SLC11A1	3527	6739
SLC15A4	2407	4647
SLC27A2	829	1635
SLC2A3	-1535	3116
SLC2A5	3250	6243
SLC44A2	6879	13182
SLCO4C1	5675	10785
SNAP23	-5681	11956
SNAP29	-703	1422
SOCS1	5053	9561
SOS1	-950	1928
SPTAN1	2385	4610
SRC	3962	7516
SRP14	-5938	12470
STAT6	-1541	3128
STBD1	-3361	7077
STK10	333	642
STK11IP	-2838	5898
STOM	-1523	3093
SUGT1	1662	3265
SURF4	-6593	13688
SVIP	2180	4238
SYNGR1	6711	12842
TAB1	6687	12789
TAB2	-3878	8201
TAB3	2566	4960
TANK	-4621	9817
TAX1BP1	-6281	13141
TBC1D10C	5382	10190
TBK1	-5169	10919
TCIRG1	180	348
TICAM1	-1956	4022
TIFA	3587	6848
TIMP2	-3938	8320
TIRAP	4446	8439
TKFC	7267	14126
TLR6	1131	2218
TLR9	-2371	4913
TMBIM1	-6493	13533
TMC6	-6114	12813
TMEM179B	-3567	7543
TMEM30A	-2956	6157
TMEM63A	3357	6449
TNFAIP3	4359	8284
TNIP2	-1314	2640
TOLLIP	-6576	13662
TOM1	-4199	8877
TOMM70	-2797	5819
TRAF2	-577	1180
TRAF3	-356	729
TRAF6	1597	3150
TRAPPC1	3089	5956
TRIM21	4105	7792
TRIM25	-5492	11574
TRIM32	5977	11376
TRIM4	-4229	8937
TRIM56	6183	11765
TSPAN14	-4626	9825
TTR	-3924	8283
TUBB	5125	9694
TUBB4B	6758	12934
TXN	-3611	7626
TXNDC5	-5385	11346
TXNIP	7384	14509
UBA3	-1275	2562
UBA52	-5068	10707
UBA7	6211	11821
UBB	-4263	9013
UBC	779	1551
UBE2D1	3523	6734
UBE2D2	-913	1857
UBE2D3	-3997	8449
UBE2K	383	750
UBE2L6	7272	14134
UBE2M	-4337	9174
UBE2N	1836	3604
UBE2V1	-4655	9900
UBR4	-6345	13266
UNC13D	-1871	3835
UNC93B1	-517	1053
VAMP8	-4969	10475
VAPA	-4898	10346
VAT1	-4497	9540
VAV2	2817	5425
VAV3	-4642	9861
VCL	4407	8357
VCP	-6720	13902
VNN1	5548	10554
VRK3	-1278	2573
VTN	6910	13246
WASF1	-5712	12021
WASF2	-3366	7096
WASF3	2619	5070
WASL	-6543	13611
WIPF2	-2965	6174
XRCC5	-4164	8806
XRCC6	28	67
YES1	-1340	2690
YPEL5	-4173	8825

---

---

Cellular response to starvation

Cellular response to starvation

metric	value
setSize	149
pMANOVA	1.93e-13
p.adjustMANOVA	1.9e-11
s.dist	0.363
s.x	-0.363
s.abs	0.00455
p.x	2.02e-14
p.abs	0.924

Top 20 genes

Gene	x	abs
ATP6V0B	-7064	14422
DDIT3	-7047	14401
FLCN	-7022	14362
RRAGC	-7009	14345
RPL36AL	-6981	14313
ATP6V1D	-6922	14228
ATP6V0D1	-6908	14206
SEC13	-6812	14049
TRIB3	-6798	14029
FNIP1	-6782	13998
RRAGD	-6743	13938
ATP6V0E1	-6622	13731
SESN2	-6610	13712
ATP6V1E1	-6271	13114
ATF2	-6175	12933
ATP6V0C	-6086	12764
CEBPG	-5987	12578
ATP6V1C2	-5929	12453
ATF4	-5664	11932
ATP6V1B2	-5574	11744

Click HERE to show all gene set members

All member genes

	x	abs
ASNS	6208	11814
ATF2	-6175	12933
ATF3	2488	4803
ATF4	-5664	11932
ATP6V0B	-7064	14422
ATP6V0C	-6086	12764
ATP6V0D1	-6908	14206
ATP6V0D2	747	1494
ATP6V0E1	-6622	13731
ATP6V0E2	5683	10798
ATP6V1A	-3777	7965
ATP6V1B1	4549	8635
ATP6V1B2	-5574	11744
ATP6V1C1	-4946	10444
ATP6V1C2	-5929	12453
ATP6V1D	-6922	14228
ATP6V1E1	-6271	13114
ATP6V1E2	-534	1090
ATP6V1F	-868	1771
ATP6V1G1	-5352	11283
ATP6V1G2	690	1360
ATP6V1H	-4423	9358
BMT2	638	1250
CEBPB	-1129	2300
CEBPG	-5987	12578
DDIT3	-7047	14401
DEPDC5	-4989	10518
EIF2AK4	-1455	2950
EIF2S1	-5190	10961
EIF2S2	-4458	9437
EIF2S3	-3669	7757
FAU	-4990	10520
FLCN	-7022	14362
FNIP1	-6782	13998
FNIP2	-5498	11587
GCN1	-4627	9826
IMPACT	4432	8414
ITFG2	2143	4172
KPTN	4478	8495
LAMTOR1	-774	1557
LAMTOR2	-148	299
LAMTOR3	-2631	5467
LAMTOR4	1834	3602
LAMTOR5	-5293	11181
MIOS	2912	5610
MLST8	1875	3677
MTOR	-3683	7785
NPRL2	4876	9247
NPRL3	4164	7917
RHEB	-3762	7936
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
RPTOR	407	803
RRAGA	2609	5038
RRAGB	-4819	10211
RRAGC	-7009	14345
RRAGD	-6743	13938
SEC13	-6812	14049
SEH1L	-4472	9474
SESN1	4963	9414
SESN2	-6610	13712
SH3BP4	-3331	7014
SLC38A9	-5539	11664
SZT2	5052	9557
TCIRG1	180	348
TRIB3	-6798	14029
UBA52	-5068	10707
WDR24	4466	8468
WDR59	4915	9316

---

---

XBP1(S) activates chaperone genes

XBP1(S) activates chaperone genes

metric	value
setSize	48
pMANOVA	3.69e-13
p.adjustMANOVA	3.38e-11
s.dist	0.643
s.x	-0.468
s.abs	0.442
p.x	2.02e-08
p.abs	1.21e-07

Top 20 genes

Gene	x	abs
DNAJB11	-7141	14528
HYOU1	-7140	14527
DNAJC3	-7131	14516
DNAJB9	-7125	14510
SYVN1	-7108	14485
PDIA6	-7106	14482
EDEM1	-7103	14479
WFS1	-7096	14466
GFPT1	-7051	14406
MYDGF	-6976	14306
SERP1	-6964	14288
WIPI1	-6942	14251
SHC1	-6910	14209
ATP6V0D1	-6908	14206
SSR1	-6907	14205
FKBP14	-6896	14184
SRPRB	-6893	14181
TSPYL2	-6784	14002
HDGF	-6715	13896
TATDN2	-6467	13480

Click HERE to show all gene set members

All member genes

	x	abs
ACADVL	4157	7903
ADD1	-5966	12538
ARFGAP1	-1587	3224
ATP6V0D1	-6908	14206
CTDSP2	-4462	9444
CUL7	4377	8310
CXXC1	-6033	12670
DCTN1	-1635	3338
DDX11	6254	11907
DNAJB11	-7141	14528
DNAJB9	-7125	14510
DNAJC3	-7131	14516
EDEM1	-7103	14479
EXTL1	6941	13312
EXTL2	3353	6440
EXTL3	3575	6822
FKBP14	-6896	14184
GFPT1	-7051	14406
GOSR2	1238	2441
GSK3A	-3684	7787
HDGF	-6715	13896
HYOU1	-7140	14527
KDELR3	976	1922
KLHDC3	-3802	8036
LMNA	-3717	7854
MYDGF	-6976	14306
PDIA5	579	1130
PDIA6	-7106	14482
PLA2G4B	4716	8953
PPP2R5B	-5131	10834
PREB	1446	2868
SEC31A	-5766	12138
SERP1	-6964	14288
SHC1	-6910	14209
SRPRA	-4802	10175
SRPRB	-6893	14181
SSR1	-6907	14205
SULT1A3	1040	2038
SYVN1	-7108	14485
TATDN2	-6467	13480
TLN1	-6146	12872
TPP1	-6407	13378
TSPYL2	-6784	14002
WFS1	-7096	14466
WIPI1	-6942	14251
XBP1	5937	11302
YIF1A	195	381
ZBTB17	-3194	6703

---

---

L13a-mediated translational silencing of Ceruloplasmin expression

L13a-mediated translational silencing of Ceruloplasmin expression

metric	value
setSize	108
pMANOVA	5.33e-13
p.adjustMANOVA	4.58e-11
s.dist	0.415
s.x	-0.404
s.abs	-0.0945
p.x	4.15e-13
p.abs	0.0902

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
EIF1AX	-274	563
EIF2S1	-5190	10961
EIF2S2	-4458	9437
EIF2S3	-3669	7757
EIF3A	-6965	14290
EIF3B	-5127	10829
EIF3C	-374	764
EIF3D	-3740	7889
EIF3E	3244	6234
EIF3F	-893	1821
EIF3G	-4724	10029
EIF3H	899	1763
EIF3I	-5279	11151
EIF3J	-4539	9629
EIF3K	-2206	4569
EIF3L	-2407	4991
EIF3M	-4358	9224
EIF4A1	-6995	14329
EIF4A2	5593	10631
EIF4B	-5898	12396
EIF4E	2473	4766
EIF4G1	-5901	12400
EIF4H	-5055	10679
FAU	-4990	10520
PABPC1	-3543	7490
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
UBA52	-5068	10707

---

---

Nervous system development

Nervous system development

metric	value
setSize	444
pMANOVA	5.72e-13
p.adjustMANOVA	4.63e-11
s.dist	0.209
s.x	-0.209
s.abs	0.0166
p.x	6.25e-14
p.abs	0.551

Top 20 genes

Gene	x	abs
VASP	-7075	14437
ABLIM1	-7055	14411
RPL36AL	-6981	14313
ETF1	-6952	14268
RNPS1	-6938	14245
ARHGEF28	-6925	14232
SHC1	-6910	14209
MET	-6878	14159
RANBP9	-6871	14151
EPHA2	-6857	14124
ACTG1	-6841	14090
GSPT1	-6825	14070
ANK2	-6778	13993
SEMA6A	-6761	13971
RHOC	-6747	13943
SCN2A	-6712	13891
SIAH2	-6666	13819
PSMF1	-6663	13810
MYL12B	-6653	13785
WASL	-6543	13611

Click HERE to show all gene set members

All member genes

	x	abs
ABL1	2023	3944
ABL2	-3020	6296
ABLIM1	-7055	14411
ABLIM2	6389	12183
ABLIM3	2675	5174
ACTB	-5057	10683
ACTG1	-6841	14090
ACTR2	1435	2855
ACTR3	-5296	11186
ADAM10	-2671	5549
ADGRG6	-428	867
ADGRV1	6861	13152
AGAP2	4399	8342
AGRN	-2369	4911
AKAP5	3035	5848
ALCAM	3171	6109
ANK1	-4656	9901
ANK2	-6778	13993
ANK3	303	591
AP2A1	-1902	3903
AP2A2	-3499	7391
AP2B1	2029	3955
AP2M1	-4603	9787
AP2S1	-2922	6073
APH1A	619	1209
APH1B	6168	11741
ARHGAP35	-6446	13445
ARHGAP39	-6303	13184
ARHGEF11	-5260	11110
ARHGEF12	-1086	2216
ARHGEF28	-6925	14232
ARHGEF7	-2913	6055
ARPC1A	3022	5822
ARPC1B	-4429	9372
ARPC2	-2209	4575
ARPC3	3797	7237
ARPC4	-6094	12778
ARPC5	-1511	3073
ARTN	973	1918
CACNA1D	-5676	11949
CACNA1H	-3915	8269
CACNB1	2967	5703
CACNB3	3735	7109
CACNB4	1983	3874
CAP1	-4085	8634
CAP2	-2694	5594
CASC3	-5986	12577
CD24	5327	10076
CDC42	-2172	4489
CDK5	-1352	2721
CDK5R1	-157	326
CFL1	-5737	12075
CLASP1	1561	3071
CLASP2	-4246	8977
CLTA	-6439	13432
CLTB	-6064	12719
CLTC	-6220	13017
CLTCL1	6404	12210
CNTN2	200	389
CNTNAP1	7239	14053
COL4A5	6694	12804
COL6A1	7322	14284
COL6A2	3222	6195
COL6A3	2085	4068
COL9A2	7348	14389
COL9A3	7151	13817
CREB1	474	935
CSNK2A1	-5040	10637
CSNK2A2	-4546	9641
CSNK2B	4415	8368
CUL2	359	703
CYP51A1	6741	12901
DAG1	-2174	4498
DLG1	-3865	8171
DLG3	5168	9763
DLG4	5108	9664
DNM1	6505	12417
DNM2	-6535	13597
DOCK1	3540	6760
DOK1	4072	7718
DOK4	-2697	5609
DOK6	-2987	6228
DPYSL2	-6519	13578
DPYSL4	1531	3019
DSCAML1	-2830	5885
EFNA1	-5830	12263
EFNA2	1735	3403
EFNA3	-1228	2484
EFNA4	3658	6973
EFNB1	3480	6658
EFNB2	-3470	7322
EFNB3	3419	6539
EGFR	-5383	11344
EGR2	-3207	6724
EIF4A3	1154	2270
EIF4G1	-5901	12400
ELOB	-3004	6272
ELOC	645	1265
ENAH	-3139	6582
EPHA1	4960	9410
EPHA10	1725	3385
EPHA2	-6857	14124
EPHB1	-5141	10858
EPHB4	-4379	9264
ERBB2	5534	10533
ETF1	-6952	14268
EVL	2467	4757
EZR	-4464	9453
FARP2	3688	7020
FAU	-4990	10520
FES	5506	10476
FGFR1	-6191	12960
FLRT3	7184	13907
FRS2	-3790	8007
FYN	1937	3783
GAB1	1575	3105
GAB2	-4127	8722
GDNF	-3969	8396
GFRA3	4393	8334
GIT1	-5582	11767
GJB1	6678	12765
GPC1	5178	9776
GRB10	-5504	11598
GRB2	-3047	6346
GRB7	-4006	8477
GRIN1	-442	902
GRIN2B	1330	2648
GSK3B	-5101	10767
GSPT1	-6825	14070
HDAC2	-338	693
HMGCR	7355	14408
HOXA2	2735	5280
HRAS	-5543	11673
HSP90AA1	-1030	2096
HSP90AB1	-4426	9363
HSPA8	-4654	9895
IRS2	-5461	11497
ITGA1	5152	9740
ITGA10	-6466	13478
ITGA2	-6205	12988
ITGA2B	-688	1391
ITGA5	587	1149
ITGAV	-4312	9120
ITGB1	-4145	8760
ITSN1	159	311
KALRN	-408	828
KIF4A	6056	11524
KRAS	-2044	4210
L1CAM	-904	1841
LAMA1	1285	2553
LAMB1	3783	7198
LAMC1	-1300	2611
LDB1	1882	3689
LIMK1	1565	3082
LIMK2	6394	12193
LYN	-3038	6328
LYPLA2	-4095	8653
MAGOH	-969	1976
MAGOHB	5814	11039
MAP2K1	-4120	8704
MAP2K2	-6087	12766
MAPK1	-5066	10705
MAPK11	251	492
MAPK12	-5538	11663
MAPK13	-1875	3846
MAPK14	2269	4391
MAPK3	6640	12684
MAPK7	-4382	9270
MAPK8	-700	1418
MBP	2888	5570
MET	-6878	14159
MMP2	-4677	9932
MPZ	7386	14523
MSI1	4326	8215
MYH10	2558	4942
MYH11	1015	1998
MYH14	5492	10431
MYH9	-4726	10036
MYL12A	-3398	7159
MYL12B	-6653	13785
MYL6	-6380	13325
MYL9	2704	5218
MYO10	-5290	11171
MYO9B	-5920	12432
NAB1	765	1529
NAB2	-6372	13315
NCBP1	-2151	4458
NCBP2	6823	13081
NCK1	1525	3010
NCK2	-3916	8271
NCSTN	-554	1137
NEO1	4016	7629
NGEF	7064	13605
NRAS	2310	4465
NRCAM	-3815	8057
NRP1	1353	2695
NRP2	-5313	11212
NRTN	3870	7357
NTN4	-1999	4099
NUMB	-5224	11036
PABPC1	-3543	7490
PAK1	1031	2021
PAK2	-4957	10458
PAK4	-5359	11295
PDLIM7	-2636	5473
PFN1	-6285	13146
PFN2	6877	13179
PIK3CA	-2813	5849
PIK3CB	-2588	5379
PIK3CD	-4759	10102
PIK3R1	-4376	9259
PIK3R2	-1355	2728
PIK3R3	-2279	4734
PIP5K1C	-3229	6778
PITPNA	-5591	11779
PLCG1	2511	4855
PLXNA1	-1050	2146
PLXNA2	-3814	8056
PLXNA3	-6318	13213
PLXNB1	-1046	2132
PLXNB3	-3778	7967
PLXNC1	4319	8196
PLXND1	-5686	11963
PMP22	7297	14203
PPP3CB	-4060	8574
PRKACA	1736	3407
PRKACB	-1429	2885
PRKAR2A	-860	1753
PRKCA	2439	4709
PRNP	-6115	12816
PRX	-2432	5042
PSEN1	-4938	10427
PSEN2	-2559	5310
PSENEN	-2327	4828
PSMA1	-5730	12052
PSMA2	-5801	12203
PSMA3	-3078	6422
PSMA4	-4211	8902
PSMA5	-2715	5657
PSMA6	-126	261
PSMA7	-892	1820
PSMB1	1054	2062
PSMB10	423	838
PSMB2	1876	3678
PSMB3	-1915	3928
PSMB4	-1144	2330
PSMB5	-742	1484
PSMB6	-4888	10326
PSMB7	-4372	9253
PSMB9	5491	10430
PSMC1	-5564	11724
PSMC2	-2389	4948
PSMC3	-1509	3070
PSMC4	-4808	10196
PSMC5	-4091	8646
PSMC6	-4878	10307
PSMD1	-5351	11280
PSMD10	4933	9356
PSMD11	-432	879
PSMD12	4303	8163
PSMD13	-2577	5353
PSMD14	5974	11371
PSMD2	-6435	13423
PSMD3	-5535	11655
PSMD4	4567	8670
PSMD5	5116	9676
PSMD6	-5951	12502
PSMD7	4942	9371
PSMD8	-2928	6091
PSMD9	-4638	9853
PSME1	-2348	4861
PSME2	-5481	11555
PSME3	-3813	8052
PSME4	-6450	13450
PSMF1	-6663	13810
PSPN	-5177	10939
PTK2	-4346	9198
PTPN11	-867	1770
PTPRA	815	1606
RAC1	44	95
RANBP9	-6871	14151
RAP1GAP	-4998	10531
RASA1	2559	4950
RBM8A	-1583	3215
RBX1	-3714	7850
RDX	1011	1989
RELN	-662	1347
RGMA	3210	6178
RGMB	1321	2630
RHOA	-5294	11182
RHOB	6064	11537
RHOC	-6747	13943
RND1	-1410	2828
RNPS1	-6938	14245
ROBO1	-5577	11752
ROBO3	4691	8903
ROCK1	-3594	7591
ROCK2	-2772	5775
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS6KA1	-3857	8159
RPS6KA2	-1149	2339
RPS6KA3	-3030	6316
RPS6KA4	731	1447
RPS6KA5	3086	5949
RPS6KA6	3918	7442
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
RRAS	-1578	3199
SCD5	3592	6855
SCN11A	-295	607
SCN1A	7327	14299
SCN1B	2398	4633
SCN2A	-6712	13891
SCN3B	2499	4826
SCN8A	249	488
SCN9A	3533	6751
SDC2	147	289
SDCBP	-1822	3724
SEM1	-3130	6566
SEMA3A	4001	7600
SEMA4D	6479	12347
SEMA6A	-6761	13971
SEMA7A	-3299	6944
SH3KBP1	-917	1864
SHANK3	935	1838
SHC1	-6910	14209
SHC3	-3782	7979
SHTN1	547	1074
SIAH1	-3347	7045
SIAH2	-6666	13819
SLIT1	886	1741
SMARCA4	-3226	6773
SOS1	-950	1928
SOS2	-5417	11402
SPTAN1	2385	4610
SPTBN1	-4901	10356
SPTBN2	3883	7379
SRC	3962	7516
SREBF2	7304	14223
SRGAP1	-1796	3662
SRGAP2	-1779	3627
SRGAP3	6775	12970
TEAD1	6440	12277
TIAM1	4452	8451
TLN1	-6146	12872
TRIO	-5341	11264
TRPC1	3602	6877
UBA52	-5068	10707
UBB	-4263	9013
UBC	779	1551
UNC5B	-6252	13071
UPF2	-3830	8093
UPF3A	-6189	12957
UPF3B	2326	4503
USP33	1924	3761
UTRN	-4105	8674
VASP	-7075	14437
VAV2	2817	5425
VAV3	-4642	9861
VLDLR	3001	5770
WASL	-6543	13611
WWTR1	-271	555
YAP1	2171	4225
YES1	-1340	2690
ZSWIM8	-5267	11127

---

---

GTP hydrolysis and joining of the 60S ribosomal subunit

GTP hydrolysis and joining of the 60S ribosomal subunit

metric	value
setSize	109
pMANOVA	9.36e-13
p.adjustMANOVA	7.16e-11
s.dist	0.409
s.x	-0.399
s.abs	-0.0881
p.x	5.93e-13
p.abs	0.113

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
EIF1AX	-274	563
EIF2S1	-5190	10961
EIF2S2	-4458	9437
EIF2S3	-3669	7757
EIF3A	-6965	14290
EIF3B	-5127	10829
EIF3C	-374	764
EIF3D	-3740	7889
EIF3E	3244	6234
EIF3F	-893	1821
EIF3G	-4724	10029
EIF3H	899	1763
EIF3I	-5279	11151
EIF3J	-4539	9629
EIF3K	-2206	4569
EIF3L	-2407	4991
EIF3M	-4358	9224
EIF4A1	-6995	14329
EIF4A2	5593	10631
EIF4B	-5898	12396
EIF4E	2473	4766
EIF4G1	-5901	12400
EIF4H	-5055	10679
EIF5	-6065	12721
EIF5B	3318	6386
FAU	-4990	10520
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
UBA52	-5068	10707

---

---

Formation of a pool of free 40S subunits

Formation of a pool of free 40S subunits

metric	value
setSize	98
pMANOVA	2.32e-12
p.adjustMANOVA	1.61e-10
s.dist	0.422
s.x	-0.397
s.abs	-0.144
p.x	1.12e-11
p.abs	0.0139

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
EIF1AX	-274	563
EIF3A	-6965	14290
EIF3B	-5127	10829
EIF3C	-374	764
EIF3D	-3740	7889
EIF3E	3244	6234
EIF3F	-893	1821
EIF3G	-4724	10029
EIF3H	899	1763
EIF3I	-5279	11151
EIF3J	-4539	9629
EIF3K	-2206	4569
EIF3L	-2407	4991
EIF3M	-4358	9224
FAU	-4990	10520
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
UBA52	-5068	10707

---

---

Cap-dependent Translation Initiation

Cap-dependent Translation Initiation

metric	value
setSize	116
pMANOVA	2.46e-12
p.adjustMANOVA	1.61e-10
s.dist	0.39
s.x	-0.38
s.abs	-0.0861
p.x	1.61e-12
p.abs	0.11

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
EIF1AX	-274	563
EIF2B1	-143	293
EIF2B2	-4811	10200
EIF2B3	5203	9835
EIF2B4	437	862
EIF2B5	-4838	10248
EIF2S1	-5190	10961
EIF2S2	-4458	9437
EIF2S3	-3669	7757
EIF3A	-6965	14290
EIF3B	-5127	10829
EIF3C	-374	764
EIF3D	-3740	7889
EIF3E	3244	6234
EIF3F	-893	1821
EIF3G	-4724	10029
EIF3H	899	1763
EIF3I	-5279	11151
EIF3J	-4539	9629
EIF3K	-2206	4569
EIF3L	-2407	4991
EIF3M	-4358	9224
EIF4A1	-6995	14329
EIF4A2	5593	10631
EIF4B	-5898	12396
EIF4E	2473	4766
EIF4EBP1	4858	9212
EIF4G1	-5901	12400
EIF4H	-5055	10679
EIF5	-6065	12721
EIF5B	3318	6386
FAU	-4990	10520
PABPC1	-3543	7490
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
UBA52	-5068	10707

---

---

Eukaryotic Translation Initiation

Eukaryotic Translation Initiation

metric	value
setSize	116
pMANOVA	2.46e-12
p.adjustMANOVA	1.61e-10
s.dist	0.39
s.x	-0.38
s.abs	-0.0861
p.x	1.61e-12
p.abs	0.11

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
EIF1AX	-274	563
EIF2B1	-143	293
EIF2B2	-4811	10200
EIF2B3	5203	9835
EIF2B4	437	862
EIF2B5	-4838	10248
EIF2S1	-5190	10961
EIF2S2	-4458	9437
EIF2S3	-3669	7757
EIF3A	-6965	14290
EIF3B	-5127	10829
EIF3C	-374	764
EIF3D	-3740	7889
EIF3E	3244	6234
EIF3F	-893	1821
EIF3G	-4724	10029
EIF3H	899	1763
EIF3I	-5279	11151
EIF3J	-4539	9629
EIF3K	-2206	4569
EIF3L	-2407	4991
EIF3M	-4358	9224
EIF4A1	-6995	14329
EIF4A2	5593	10631
EIF4B	-5898	12396
EIF4E	2473	4766
EIF4EBP1	4858	9212
EIF4G1	-5901	12400
EIF4H	-5055	10679
EIF5	-6065	12721
EIF5B	3318	6386
FAU	-4990	10520
PABPC1	-3543	7490
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
UBA52	-5068	10707

---

---

Disease

Disease

metric	value
setSize	1247
pMANOVA	2.59e-12
p.adjustMANOVA	1.62e-10
s.dist	0.127
s.x	-0.114
s.abs	0.055
p.x	2.4e-11
p.abs	0.0013

Top 20 genes

Gene	x	abs
CALR	-7142	14529
DNAJC3	-7131	14516
SLC2A1	-7130	14515
SLC3A2	-7128	14513
SEL1L	-7124	14508
SYVN1	-7108	14485
CANX	-7092	14462
ANTXR2	-7077	14440
SLC17A5	-7072	14434
ARRB1	-7062	14420
GFPT1	-7051	14406
DERL2	-7046	14399
MAGT1	-7045	14398
MAP1LC3B	-7040	14388
RAMP1	-7037	14385
EIF2AK3	-7028	14371
RPN1	-7013	14350
SLC33A1	-7011	14348
SQSTM1	-7010	14347
OS9	-6986	14320

Click HERE to show all gene set members

All member genes

	x	abs
AAAS	2965	5701
ABCA1	-2289	4752
ABCA3	3033	5842
ABCA4	138	271
ABCB4	-6800	14032
ABCB6	-2491	5157
ABCC2	-6611	13713
ABCC6	4285	8124
ABCC9	3136	6037
ABCD1	-6246	13062
ABCD4	5258	9940
ABCG5	6607	12609
ABCG8	2955	5687
ABI1	-4478	9492
ABI2	-1197	2431
ABL1	2023	3944
ACACA	118	236
ACE2	2757	5319
ACTB	-5057	10683
ACTG1	-6841	14090
ACTR2	1435	2855
ACTR3	-5296	11186
ACY1	4275	8112
ADAM10	-2671	5549
ADAM17	-5836	12276
ADAMTS1	3770	7179
ADAMTS10	6971	13383
ADAMTS13	5043	9541
ADAMTS17	-2445	5058
ADAMTS2	6939	13309
ADAMTS4	1241	2448
ADAMTS6	6501	12405
ADAMTS7	2880	5554
ADAMTS9	6402	12207
ADAMTSL2	-3475	7330
ADAMTSL3	2956	5688
ADAMTSL4	7040	13538
ADAMTSL5	-1090	2224
ADCY1	4808	9122
ADCY2	-667	1356
ADCY6	-2818	5862
ADCY7	6316	12040
ADCY9	4287	8130
ADM	-2543	5276
ADM2	-6068	12730
ADORA2A	5330	10081
ADORA2B	5127	9698
AGGF1	3135	6035
AGK	2062	4016
AGRN	-2369	4911
AGTRAP	5793	11004
AHCY	-1945	3991
AHCYL1	4874	9245
AKAP9	5113	9671
AKT1	-2958	6160
AKT1S1	-5990	12584
AKT2	-1946	3993
ALDOB	1990	3886
ALG1	-4352	9207
ALG11	-5957	12520
ALG12	-6081	12752
ALG13	1348	2687
ALG14	-3206	6723
ALG2	-6554	13631
ALG3	-6601	13700
ALG6	4943	9374
ALG8	1117	2188
ALG9	-426	865
AMER1	5007	9484
AMN	-881	1802
ANAPC1	1998	3900
ANAPC10	6071	11551
ANAPC11	-1544	3134
ANAPC15	-4945	10442
ANAPC16	6307	12018
ANAPC2	-1639	3349
ANAPC4	305	595
ANAPC5	3942	7485
ANAPC7	6249	11895
ANTXR1	4532	8605
ANTXR2	-7077	14440
AP1B1	940	1849
AP1G1	-1916	3931
AP1M1	2926	5637
AP1M2	914	1788
AP1S1	5804	11022
AP1S2	-4204	8889
AP1S3	-739	1480
AP2A1	-1902	3903
AP2A2	-3499	7391
AP2B1	2029	3955
AP2M1	-4603	9787
AP2S1	-2922	6073
AP3B1	13	31
APC	-1818	3716
APH1A	619	1209
APH1B	6168	11741
APOA1	6993	13433
APOBEC3G	7066	13607
APP	-6492	13532
ARAF	-5242	11076
AREG	-4847	10258
ARF1	-6021	12642
ARID4A	-156	323
ARID4B	480	945
ARPC1A	3022	5822
ARPC1B	-4429	9372
ARPC2	-2209	4575
ARPC3	3797	7237
ARPC4	-6094	12778
ARPC5	-1511	3073
ARRB1	-7062	14420
ARRB2	-3248	6824
ARSB	-6939	14246
ATG7	5453	10354
ATIC	-520	1065
ATM	1503	2965
ATP1A1	-6777	13992
ATP1A3	-1706	3489
ATP1A4	412	810
ATP1B1	-6624	13734
ATP1B2	-3692	7805
ATP1B3	-6941	14249
ATP6V1H	-4423	9358
ATRX	2556	4939
AXIN1	-4215	8908
B2M	-2523	5242
B3GALT6	-4868	10295
B3GAT3	-3209	6727
B3GLCT	-5422	11411
B4GALT1	-262	540
B4GALT7	4091	7764
B4GAT1	-3691	7803
BAD	-6118	12822
BAG4	4019	7633
BAIAP2	-637	1295
BANF1	3790	7227
BARD1	6138	11687
BCL2L1	-6349	13271
BCL2L11	-3834	8099
BCR	-2502	5190
BECN1	-2900	6036
BGN	5087	9620
BIRC6	-3068	6387
BLM	5994	11423
BRAF	-4749	10077
BRAP	1211	2384
BRCA1	5107	9663
BRCA2	5396	10219
BRD4	-6479	13501
BRIP1	6392	12189
BRK1	-5431	11428
BRMS1	-6309	13195
BSG	-4895	10339
BTD	-4207	8893
BTRC	1386	2757
C1GALT1	742	1485
C1GALT1C1	-2939	6112
C1QBP	-682	1380
C3	7357	14417
CALM1	-655	1340
CALR	-7142	14529
CAMK2A	4566	8669
CAMK2D	1711	3358
CAMK2G	2145	4176
CAMK4	4196	7978
CANX	-7092	14462
CAPN1	-5850	12305
CAPN2	-3774	7962
CAPNS1	-4414	9343
CASP1	6109	11631
CASP8	3157	6085
CASP9	-5247	11084
CAST	-381	778
CBL	-5708	12008
CBLL1	-5694	11979
CBX1	4668	8861
CCNC	-2471	5121
CCND1	-137	277
CCND2	-3838	8117
CCND3	-2677	5565
CCNE1	2754	5315
CCNE2	-2024	4152
CCNH	5556	10565
CCNK	-1089	2223
CCNT1	-4690	9958
CCNT2	4117	7818
CD14	6998	13442
CD19	-472	954
CD320	-3680	7781
CD36	5264	9953
CD4	6074	11557
CD9	-3660	7746
CDC16	1175	2309
CDC23	6113	11639
CDC25A	5954	11334
CDC25B	6275	11958
CDC25C	6825	13084
CDC26	-197	402
CDC27	-1529	3103
CDC37	-5178	10941
CDC42	-2172	4489
CDH1	7296	14202
CDK2	4114	7809
CDK4	-5064	10698
CDK5	-1352	2721
CDK5R1	-157	326
CDK6	4754	9023
CDK7	-5444	11458
CDK8	-4276	9040
CDK9	2631	5091
CDKN1A	-3580	7569
CDKN1B	-786	1590
CDKN2A	3704	7056
CEBPB	-1129	2300
CEBPD	6867	13165
CHD3	-1321	2661
CHD4	-4830	10236
CHMP1A	-5693	11973
CHMP2A	-1088	2222
CHMP2B	-878	1797
CHMP3	1229	2417
CHMP4A	909	1779
CHMP4B	-5021	10594
CHMP4C	-6557	13640
CHMP5	-1722	3519
CHMP6	5904	11222
CHMP7	2690	5197
CHST14	6461	12314
CHST3	2703	5217
CHST6	5182	9782
CHSY1	-4336	9172
CHUK	-3364	7086
CLCN6	3165	6094
CLTA	-6439	13432
CLTC	-6220	13017
CNKSR1	3649	6956
CNTRL	6358	12110
COMT	2597	5019
CORO1A	3359	6451
CP	7325	14292
CPSF4	1570	3094
CPSF6	-4789	10151
CRBN	-1928	3959
CREB1	474	935
CREBBP	-3888	8214
CRK	-5650	11901
CSF2RA	43	94
CSK	-4113	8692
CSNK1A1	-5349	11277
CTBP1	-41	73
CTBP2	-4982	10508
CTDP1	-4461	9443
CTNNB1	3272	6288
CTNND1	7129	13781
CTSA	-6288	13149
CTSL	-6951	14263
CUBN	854	1678
CUL1	-4129	8725
CUL3	-3056	6363
CUL5	-1229	2485
CUX1	-1665	3398
CYBA	2202	4283
CYFIP1	1939	3785
CYFIP2	6224	11850
CYP11A1	5667	10772
CYP17A1	-380	777
CYP19A1	6444	12287
CYP21A2	4343	8249
CYP24A1	2409	4653
CYP26B1	-4218	8914
CYP27A1	-3786	7994
CYP27B1	-5723	12039
CYP2R1	3494	6680
CYP2U1	5991	11416
CYSLTR1	2493	4813
DAD1	-6240	13053
DAG1	-2174	4498
DAXX	3635	6929
DBP	-2002	4112
DCTN1	-1635	3338
DCXR	-3525	7446
DDOST	-6429	13410
DDX5	-6665	13814
DERL1	-6423	13398
DERL2	-7046	14399
DHDDS	2399	4636
DKK1	4410	8362
DKK4	-5490	11570
DNA2	3379	6486
DNAJC3	-7131	14516
DNMT1	2134	4159
DNMT3A	3360	6452
DNMT3B	6957	13348
DOCK1	3540	6760
DOLK	108	213
DPAGT1	-6046	12688
DPEP1	-3163	6625
DPM1	-1233	2494
DPM2	-2111	4373
DPM3	3217	6189
DRD5	4609	8753
DUSP10	-5271	11134
DUSP16	-1750	3571
DUSP6	-3376	7113
DUSP7	-3870	8185
DUSP8	4879	9251
DUSP9	-284	580
DUT	6636	12668
DVL1	-2264	4696
DVL2	-905	1843
DVL3	-6967	14293
DYNC1H1	-3614	7639
DYNC1I2	-2780	5783
DYNC1LI1	-2519	5237
DYNC1LI2	-3897	8235
DYNLL1	2509	4853
DYNLL2	6044	11507
E2F1	7096	13694
E2F2	6426	12251
E2F3	444	876
EDEM2	-5520	11628
EED	2369	4581
EEF1G	-3612	7628
EEF2	-5049	10659
EGFR	-5383	11344
EIF2AK2	2886	5562
EIF2AK3	-7028	14371
ELK1	-5733	12060
ELL	-1439	2915
ELMO1	-2779	5782
ELMO2	942	1854
ELOA	-2831	5887
ELOB	-3004	6272
ELOC	645	1265
EML4	27	66
ENO1	-4866	10290
ENTPD1	184	358
ENTPD5	3958	7507
EP300	-6470	13485
EPM2A	5000	9471
EPS15	1254	2479
ERBB2	5534	10533
ERBB3	4249	8072
ERBIN	-2316	4809
ERCC2	-583	1192
ERCC3	-2013	4129
EREG	3467	6635
ERLEC1	-6168	12918
ERLIN1	3212	6181
ERLIN2	5405	10235
ESR2	3316	6378
ETV6	-1588	3225
EXO1	6663	12733
EXT1	-2144	4444
EXT2	5580	10604
EZH2	-5631	11860
F10	5732	10888
F11	4836	9173
F12	6397	12198
F2	635	1246
F8	735	1460
FADD	1889	3704
FAM114A2	6340	12078
FAU	-4990	10520
FBXW7	-2564	5325
FDX1	2458	4743
FDX2	285	557
FDXR	3064	5910
FEN1	367	721
FGA	7336	14346
FGB	7226	14018
FGF17	-4015	8493
FGF23	2097	4091
FGF5	342	659
FGFR1	-6191	12960
FGFR1OP2	-6202	12984
FGFR2	6811	13048
FGFR3	-1195	2426
FGFR4	-2795	5810
FGG	6697	12809
FIP1L1	-5876	12362
FKBP1A	-5189	10960
FKBP4	-5807	12213
FLT3LG	6000	11436
FMO3	142	281
FN1	-3115	6525
FNTA	-6282	13142
FNTB	-2551	5296
FOXO1	5418	10275
FOXO3	2282	4415
FOXO4	-2077	4276
FRS2	-3790	8007
FRS3	2112	4125
FURIN	-6683	13851
FUT8	-5134	10839
FXR1	-4803	10176
FXYD1	-2847	5919
FXYD2	-5865	12339
FYN	1937	3783
FZD4	6534	12474
FZD5	4841	9179
FZD6	6312	12029
FZD7	5487	10425
FZD8	2263	4376
FZR1	201	397
G6PC3	1108	2174
GAA	4697	8919
GAB1	1575	3105
GAB2	-4127	8722
GALE	2553	4935
GALK1	7177	13889
GALNS	-6314	13205
GALNT1	-816	1659
GALNT3	-3227	6774
GALT	6341	12080
GANAB	2813	5417
GATAD2A	-4108	8682
GATAD2B	-1092	2228
GBE1	-3927	8293
GCC2	-597	1225
GCKR	7281	14160
GCLC	-6903	14194
GCLM	2237	4335
GFPT1	-7051	14406
GGCX	-4023	8504
GGT1	-250	514
GGT5	-4012	8488
GIPR	3556	6793
GLB1	1557	3064
GNAI1	-2495	5167
GNAI2	-3904	8246
GNAI3	-4609	9793
GNAS	459	900
GNAZ	-3724	7864
GNB1	-3237	6796
GNB2	-4514	9583
GNB3	-1008	2063
GNB4	1936	3781
GNB5	700	1388
GNE	6051	11517
GNG10	6779	12977
GNG4	6164	11731
GNG5	4123	7830
GNG7	4426	8395
GNS	-6813	14052
GOLGA2	-5310	11209
GOLGA4	-4624	9822
GOLGB1	-3498	7386
GPC1	5178	9776
GPC2	5828	11063
GPC3	4191	7971
GPC4	952	1874
GPC6	4318	8195
GPHA2	-3711	7837
GPR176	5289	10004
GPR39	994	1956
GPR83	1350	2691
GPS2	-4524	9607
GRB2	-3047	6346
GRSF1	-4747	10070
GSDMD	5413	10266
GSK3A	-3684	7787
GSK3B	-5101	10767
GSS	3160	6088
GTF2A1	328	633
GTF2A2	5445	10341
GTF2B	-5704	11995
GTF2E1	5502	10461
GTF2E2	-5813	12227
GTF2F1	-3103	6481
GTF2F2	4556	8650
GTF2H1	-5744	12095
GTF2H2	5321	10066
GTF2H3	6024	11478
GTF2H4	-406	824
GTF2H5	4373	8306
GUSB	1260	2493
GYG1	-1167	2373
GYG2	1023	2010
GYS1	3798	7238
H2AFX	5356	10131
HBEGF	-4402	9320
HDAC1	-2676	5563
HDAC10	-1408	2826
HDAC11	1004	1970
HDAC2	-338	693
HDAC3	38	84
HDAC4	-1478	2998
HDAC5	-4034	8527
HDAC6	5953	11333
HDAC7	130	254
HDAC8	3835	7301
HES1	7265	14121
HEXA	-4335	9171
HEXB	-6455	13459
HEY1	-3864	8169
HGS	-4210	8898
HGSNAT	5921	11261
HHAT	4068	7712
HIP1	7319	14277
HK1	-6574	13660
HLA-A	5777	10971
HLCS	-1769	3609
HMG20B	-3184	6676
HMGA1	-5226	11043
HMGB1	5546	10552
HMOX1	4592	8715
HNRNPK	-2808	5839
HRAS	-5543	11673
HSP90AA1	-1030	2096
HSP90AB1	-4426	9363
HSPA1A	1835	3603
HSPG2	7157	13832
HTR7	-5841	12283
HYAL1	2604	5029
IDH1	-5470	11528
IDS	-4768	10121
IDUA	5809	11033
IFNAR1	4161	7910
IFNAR2	-2313	4798
IFNGR1	1624	3204
IFNGR2	997	1962
IHH	-4252	8989
IKBKB	-2931	6100
IKBKG	-5946	12493
IL18	2102	4103
IL1R1	6510	12430
IL6R	-4943	10440
IMPDH1	-1807	3690
IMPDH2	4910	9308
IPO5	-6366	13302
IQGAP1	-5663	11931
IRAK4	1591	3137
IRS1	3502	6691
IRS2	-5461	11497
ISG15	-5488	11568
ITGA2B	-688	1391
ITGB1	-4145	8760
ITPR1	-4321	9146
ITPR2	2257	4366
ITPR3	-6088	12768
JAG1	-6948	14259
JAG2	-516	1048
JAK1	-4963	10468
JAK2	-2719	5664
JAK3	7326	14295
JUN	-2934	6103
JUNB	-3526	7447
KANK1	4837	9175
KAT2A	5077	9597
KAT2B	-4792	10158
KAT5	1580	3115
KCNJ11	4499	8545
KDM1A	4224	8018
KDM7A	-6055	12709
KEAP1	-6482	13510
KHK	6286	11987
KIAA1549	-5776	12155
KIF5B	-5426	11419
KITLG	92	180
KLB	-3807	8045
KLC1	4611	8755
KLKB1	1361	2707
KPNA1	-6701	13876
KPNA2	-4575	9708
KPNA3	-4357	9223
KPNA4	-1701	3478
KPNA5	258	506
KPNB1	-6379	13324
KRAS	-2044	4210
KREMEN1	364	715
KREMEN2	-791	1609
KSR1	-1	5
LARGE1	-5056	10682
LCK	-6250	13069
LFNG	-1376	2769
LIG1	6206	11811
LIG4	6454	12304
LMBRD1	-6198	12979
LMNA	-3717	7854
LMNB1	7101	13707
LMO7	-1246	2512
LRAT	2585	4994
LRP5	-2319	4812
LRP6	-4613	9800
LRRFIP1	-5477	11545
LY96	-1339	2689
LYN	-3038	6328
MAGT1	-7045	14398
MAML1	-6891	14179
MAML2	6847	13122
MAN1B1	-3561	7534
MAN2A1	-1040	2117
MAOA	-3288	6912
MAP1LC3B	-7040	14388
MAP2K1	-4120	8704
MAP2K2	-6087	12766
MAP2K3	-3342	7038
MAP2K4	-4505	9558
MAP2K6	-2351	4868
MAP2K7	-4399	9311
MAP3K11	-4272	9031
MAPK1	-5066	10705
MAPK14	2269	4391
MAPK3	6640	12684
MAPK8	-700	1418
MAPKAP1	-5936	12466
MARK3	-3996	8448
MAT1A	6114	11641
MBD3	-4543	9635
MC1R	7078	13634
MCCC1	-5566	11728
MCCC2	-2365	4899
MDM2	-956	1942
MECP2	-4891	10331
MEFV	2468	4758
MET	-6878	14159
MGAT1	-6401	13371
MGAT2	-3327	7002
MGAT4A	-5018	10584
MGAT4B	-6279	13132
MGAT4C	1714	3364
MGAT5	-5854	12324
MIB1	1650	3250
MIB2	-4356	9222
MLH1	1370	2724
MLST8	1875	3677
MMAA	1953	3808
MMAB	7195	13940
MMACHC	4886	9266
MMADHC	5435	10322
MNAT1	-205	420
MOGS	-2275	4728
MPDU1	3718	7080
MPI	5076	9596
MPRIP	-266	545
MRAS	5118	9679
MRE11	4100	7780
MSH2	4066	7708
MSH3	-255	528
MSH6	450	883
MTA1	1810	3553
MTA2	-5619	11843
MTA3	6411	12223
MTOR	-3683	7785
MTR	6057	11525
MTRR	1240	2447
MUC13	-1524	3097
MUC15	4828	9153
MUC20	-1019	2082
MUC5B	7378	14487
MUTYH	6556	12512
MVB12A	5589	10620
MVB12B	-3629	7683
MYC	1892	3708
MYD88	5939	11305
MYH9	-4726	10036
MYO10	-5290	11171
MYO18A	3903	7411
MYO1C	-1212	2457
MYO5A	-3500	7394
MYO9B	-5920	12432
NAGLU	-4398	9309
NAPEPLD	-1467	2977
NBN	4533	8606
NCBP1	-2151	4458
NCBP2	6823	13081
NCK1	1525	3010
NCKAP1	-2788	5794
NCKAP1L	-972	1980
NCKIPSD	5477	10395
NCOR1	-4374	9256
NCOR2	-4409	9331
NCSTN	-554	1137
NDC1	-1490	3023
NEDD4L	7233	14037
NEIL1	6345	12085
NEIL3	6230	11865
NELFA	-5284	11161
NELFB	-2298	4775
NELFCD	-3765	7941
NELFE	26	63
NEU1	-6752	13953
NEURL1B	3778	7190
NF1	1648	3245
NFE2L2	-2108	4363
NFKB1	-3507	7409
NFKB2	-1311	2634
NFKBIA	-6437	13427
NMT1	-2085	4289
NMT2	1894	3710
NOTCH1	-3923	8281
NOTCH2	6231	11869
NOTCH3	4292	8138
NOXA1	5500	10451
NOXO1	10	21
NPM1	-2033	4183
NR3C1	-4005	8476
NR4A1	3691	7026
NRAS	2310	4465
NT5E	-6296	13160
NTHL1	3521	6732
NUP107	6076	11561
NUP133	1362	2708
NUP153	2712	5230
NUP155	4796	9102
NUP160	-329	683
NUP188	-4991	10521
NUP205	-5275	11144
NUP210	6802	13025
NUP214	-1926	3957
NUP35	5982	11387
NUP37	7100	13706
NUP43	2808	5410
NUP50	-4733	10047
NUP54	3310	6371
NUP58	2380	4603
NUP62	-299	618
NUP85	4178	7946
NUP88	-4777	10134
NUP93	5831	11067
NUP98	-3764	7940
NUS1	-6395	13362
OGG1	3917	7441
OPLAH	5314	10049
OS9	-6986	14320
P2RX4	5401	10229
P2RY11	-6403	13374
PABPN1	-2037	4195
PACS1	414	814
PAH	-3408	7178
PAK2	-4957	10458
PALB2	4305	8170
PAPSS1	3746	7130
PAPSS2	1548	3052
PARP1	2974	5715
PARP10	5859	11125
PARP14	5386	10194
PARP16	-3842	8129
PARP4	462	908
PARP6	-1567	3181
PARP8	3263	6264
PARP9	6988	13424
PC	-5292	11179
PCCA	-6623	13733
PCCB	1766	3460
PDCD6IP	-5380	11336
PDGFA	-2660	5524
PDGFB	6920	13263
PDGFRB	-6820	14062
PDPK1	399	782
PEBP1	-6972	14300
PGK1	-4810	10198
PGM1	-4600	9783
PHB	-4920	10399
PHF21A	-1078	2202
PIK3AP1	-6957	14273
PIK3C3	-5220	11026
PIK3CA	-2813	5849
PIK3CB	-2588	5379
PIK3CD	-4759	10102
PIK3R1	-4376	9259
PIK3R2	-1355	2728
PIK3R3	-2279	4734
PIK3R4	1132	2219
PIM1	-4092	8647
PLCG1	2511	4855
PLCG2	-3766	7942
PLK2	-5005	10551
PML	1051	2057
PMM2	-5187	10956
PMS2	3890	7389
POLA1	4949	9387
POLA2	6695	12805
POLR2A	2705	5219
POLR2B	-3699	7815
POLR2C	-3425	7212
POLR2D	2418	4674
POLR2E	-4667	9916
POLR2F	-5283	11158
POLR2G	2003	3910
POLR2H	-3593	7590
POLR2I	4594	8717
POLR2J	-603	1234
POLR2K	5962	11350
POLR2L	-5471	11530
POM121	-6353	13281
POM121C	-6045	12687
POMGNT1	3215	6187
POMT1	-3914	8266
POMT2	-6788	14007
PORCN	320	622
PPFIBP1	-3970	8397
PPIA	-4443	9393
PPM1B	-5398	11375
PPP1CB	-3630	7685
PPP1CC	-3392	7149
PPP1R3C	6692	12799
PPP2CA	-5168	10917
PPP2CB	-4523	9606
PPP2R1A	-4744	10064
PPP2R1B	4614	8759
PPP2R5A	-5740	12088
PPP2R5B	-5131	10834
PPP2R5C	2743	5293
PPP2R5D	-2117	4385
PPP2R5E	283	554
PRDX1	-6673	13828
PRDX2	-961	1951
PRELP	546	1073
PRIM1	6962	13355
PRIM2	6599	12596
PRKACA	1736	3407
PRKACB	-1429	2885
PRKAR1A	4	6
PRKAR1B	-1038	2113
PRKAR2A	-860	1753
PRKCSH	-5934	12463
PRKX	-553	1134
PRMT1	-4281	9055
PRR5	-2094	4323
PSEN1	-4938	10427
PSEN2	-2559	5310
PSENEN	-2327	4828
PSIP1	7193	13933
PSMA1	-5730	12052
PSMA2	-5801	12203
PSMA3	-3078	6422
PSMA4	-4211	8902
PSMA5	-2715	5657
PSMA6	-126	261
PSMA7	-892	1820
PSMB1	1054	2062
PSMB10	423	838
PSMB2	1876	3678
PSMB3	-1915	3928
PSMB4	-1144	2330
PSMB5	-742	1484
PSMB6	-4888	10326
PSMB7	-4372	9253
PSMB9	5491	10430
PSMC1	-5564	11724
PSMC2	-2389	4948
PSMC3	-1509	3070
PSMC4	-4808	10196
PSMC5	-4091	8646
PSMC6	-4878	10307
PSMD1	-5351	11280
PSMD10	4933	9356
PSMD11	-432	879
PSMD12	4303	8163
PSMD13	-2577	5353
PSMD14	5974	11371
PSMD2	-6435	13423
PSMD3	-5535	11655
PSMD4	4567	8670
PSMD5	5116	9676
PSMD6	-5951	12502
PSMD7	4942	9371
PSMD8	-2928	6091
PSMD9	-4638	9853
PSME1	-2348	4861
PSME2	-5481	11555
PSME3	-3813	8052
PSME4	-6450	13450
PSMF1	-6663	13810
PSTPIP1	5948	11328
PTEN	-4721	10023
PTGES3	3734	7103
PTHLH	-6042	12681
PTK2	-4346	9198
PTPN11	-867	1770
PTPN12	-5326	11236
PYCARD	6900	13221
QKI	-5427	11421
RAB5A	-5408	11392
RAB7A	-5810	12220
RAC1	44	95
RAD50	-4078	8623
RAD51	6326	12057
RAD51AP1	7241	14061
RAD51B	4156	7901
RAD51C	6033	11490
RAD51D	6153	11713
RAE1	4394	8335
RAF1	-5557	11708
RAMP1	-7037	14385
RAMP2	6288	11990
RAN	-6476	13497
RANBP1	1308	2605
RANBP2	-4	9
RANGAP1	3458	6615
RAP1A	309	604
RAP1B	3577	6830
RB1	470	925
RBBP4	-3297	6938
RBBP7	5134	9712
RBBP8	3824	7280
RBP1	-3386	7136
RBP4	7308	14250
RBPJ	4794	9099
RBX1	-3714	7850
RCC1	-2159	4473
RCOR1	-3493	7376
RDH12	5744	10909
RDH5	5315	10055
RELA	-2632	5468
REST	-593	1214
RFT1	5083	9608
RHBDF2	-3089	6446
RHOG	-2756	5747
RICTOR	-2076	4274
RIPK1	-2886	6000
RMI1	3620	6903
RMI2	7209	13969
RNF185	-6359	13291
RNF213	5584	10611
RNF43	1197	2353
RNF5	-6629	13745
RNGTT	-4400	9314
RNMT	4440	8428
ROCK1	-3594	7591
ROCK2	-2772	5775
RPIA	3101	5974
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPN1	-7013	14350
RPN2	-6193	12964
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS6KB2	-3901	8241
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
RRBP1	-6551	13627
S100A1	6858	13138
SAP18	-3349	7051
SAP30	-5230	11054
SAP30L	-3887	8212
SDC1	2160	4201
SDC2	147	289
SDC3	4241	8055
SDC4	-2147	4450
SEC13	-6812	14049
SEC31A	-5766	12138
SEH1L	-4472	9474
SEL1L	-7124	14508
SEM1	-3130	6566
SERPING1	7387	14532
SFPQ	-6854	14118
SFTPB	-720	1453
SGSH	1472	2908
SH3GL1	-4200	8879
SH3KBP1	-917	1864
SHC1	-6910	14209
SHH	-3305	6953
SHOC2	-749	1499
SIGMAR1	753	1508
SIN3A	-5884	12373
SKP1	-544	1117
SKP2	5946	11323
SLC11A2	-3217	6749
SLC12A6	-6223	13027
SLC16A1	4057	7693
SLC17A5	-7072	14434
SLC20A2	-2599	5400
SLC22A18	262	512
SLC22A5	-1944	3989
SLC24A1	5215	9854
SLC24A4	2892	5578
SLC25A4	-3203	6719
SLC25A5	-4001	8466
SLC25A6	-3733	7878
SLC26A2	2580	4985
SLC26A3	83	165
SLC27A4	-1101	2241
SLC29A3	-456	930
SLC2A1	-7130	14515
SLC2A10	4273	8109
SLC2A2	7259	14109
SLC2A9	-1899	3896
SLC33A1	-7011	14348
SLC34A3	-4411	9335
SLC35A1	3906	7418
SLC35A2	-2730	5685
SLC35A3	4972	9426
SLC35C1	-6667	13821
SLC35D1	3595	6862
SLC37A4	5575	10598
SLC39A4	6798	13020
SLC3A1	-1764	3595
SLC3A2	-7128	14513
SLC40A1	-2061	4248
SLC4A1	141	280
SLC5A2	3524	6735
SLC6A14	695	1374
SLC6A2	-6609	13711
SLC6A20	876	1719
SLC7A7	2968	5704
SLC7A9	2093	4084
SLC9A6	-5075	10721
SLCO1B3	4370	8303
SLCO2A1	4980	9440
SMAD2	-4087	8639
SMAD3	-6145	12871
SMAD4	2742	5290
SND1	-6000	12607
SNF8	-1198	2432
SNW1	-5581	11762
SOD2	7342	14367
SOS1	-950	1928
SPON2	-6404	13375
SPRED1	-2574	5348
SPRED2	-2862	5946
SPRED3	-3905	8248
SPTBN1	-4901	10356
SQSTM1	-7010	14347
SRC	3962	7516
SRD5A3	4758	9027
SRPK1	3007	5798
SRPK2	-1905	3907
SSRP1	-4525	9609
ST3GAL1	-5905	12408
ST3GAL2	-4518	9594
ST3GAL3	5918	11257
ST3GAL4	-6801	14033
ST6GAL1	-1828	3739
ST6GALNAC4	-6726	13912
STAM	5109	9665
STAM2	3080	5933
STAT1	-5668	11938
STAT2	76	146
STAT3	4253	8078
STAT5A	5288	10000
STAT5B	6572	12541
STRA6	1551	3056
STRN	-5363	11300
STT3A	-6796	14026
STX1A	-2377	4922
STX1B	1841	3612
SUDS3	-2287	4748
SUGT1	1662	3265
SUMO1	3308	6365
SUPT16H	3202	6161
SUPT4H1	-2826	5881
SUPT5H	-5767	12140
SUZ12	346	664
SV2A	2966	5702
SYVN1	-7108	14485
TAF1	788	1565
TAF10	626	1223
TAF11	-429	868
TAF12	6601	12600
TAF13	-5280	11153
TAF15	7061	13593
TAF2	-206	426
TAF3	-1222	2472
TAF4	-6108	12802
TAF4B	-4483	9500
TAF5	-2960	6167
TAF6	1145	2253
TAF7	-1012	2071
TAF9	-483	981
TAF9B	6106	11625
TALDO1	-5554	11703
TBK1	-5169	10919
TBL1X	-1621	3308
TBL1XR1	1404	2795
TBP	3968	7524
TBXAS1	4766	9044
TCEA1	-6409	13380
TCF7L2	959	1893
TCN2	3151	6075
TFDP1	-2579	5361
TFDP2	4856	9210
TFG	-5336	11250
TGFA	-4511	9574
TGFB1	-6934	14241
TGFBR1	-2620	5447
TGFBR2	-3644	7714
THBS1	5988	11408
THBS2	2512	4856
THSD1	-5333	11244
THSD4	-6356	13286
TICAM1	-1956	4022
TIRAP	4446	8439
TLN1	-6146	12872
TLR6	1131	2218
TLR9	-2371	4913
TMPRSS2	1456	2886
TNKS	-4790	10153
TNKS2	-3213	6742
TOP3A	-2378	4927
TP53	-2020	4144
TPM3	-40	71
TPM4	-822	1674
TPMT	-2290	4759
TPR	565	1105
TPST1	-2126	4399
TPST2	-2873	5975
TRADD	3885	7383
TRAF2	-577	1180
TRAF3	-356	729
TRAK1	3646	6949
TRIM24	-4887	10323
TRIM27	-4835	10241
TRIM28	-3099	6471
TRIP11	-990	2024
TSC2	-2462	5097
TSG101	-2130	4411
TTR	-3924	8283
TUBB	5125	9694
TUSC3	-1219	2465
TXN	-3611	7626
TXNIP	7384	14509
TXNRD1	-6806	14041
TYK2	5066	9579
UBA52	-5068	10707
UBAP1	-1894	3882
UBB	-4263	9013
UBC	779	1551
UBE2C	7137	13793
UBE2D1	3523	6734
UBE2E1	3733	7102
UBE2I	-1318	2653
UBE2S	-1872	3839
UGT1A1	2676	5176
UNC93B1	-517	1053
UVRAG	-6290	13151
VAMP1	3484	6665
VAMP2	-5088	10744
VAV2	2817	5425
VAV3	-4642	9861
VCAN	-5649	11899
VCL	4407	8357
VCP	-6720	13902
VEGFA	-4456	9433
VHL	-6491	13531
VPS25	2895	5587
VPS28	4152	7894
VPS33B	4043	7662
VPS36	2474	4767
VPS37A	-4187	8850
VPS37B	-4696	9967
VPS37C	-4620	9815
VPS37D	809	1599
VPS4A	2374	4592
VPS4B	-934	1894
VTA1	1653	3254
VWF	1933	3777
WASF1	-5712	12021
WASF2	-3366	7096
WASF3	2619	5070
WASL	-6543	13611
WDCP	6637	12675
WDR48	543	1063
WIPF2	-2965	6174
WRN	3032	5841
XPO1	-1864	3824
XRCC2	6513	12436
XRCC4	3376	6479
XRCC5	-4164	8806
XRCC6	28	67
YES1	-1340	2690
YWHAB	2082	4062
YWHAE	129	253
ZC3HAV1	4414	8366
ZC3HC1	5790	10991
ZCRB1	4731	8981
ZFYVE9	1407	2801
ZMYM2	2755	5316

---

---

DNA strand elongation

DNA strand elongation

metric	value
setSize	32
pMANOVA	3.14e-12
p.adjustMANOVA	1.88e-10
s.dist	0.729
s.x	0.602
s.abs	0.411
p.x	3.66e-09
p.abs	5.82e-05

Top 20 genes

Gene	x	abs
GINS1	7335	14342
MCM5	6983	13415
PRIM1	6962	13355
RPA2	6961	13354
GINS2	6909	13245
MCM6	6787	12996
GINS3	6759	12937
MCM2	6755	12926
POLA2	6695	12805
MCM4	6635	12667
PRIM2	6599	12596
GINS4	6560	12516
PCNA	6523	12452
RPA3	6375	12149
LIG1	6206	11811
POLD1	5832	11069
RFC3	5349	10111
POLA1	4949	9387
POLD2	4930	9350
MCM3	4773	9054

Click HERE to show all gene set members

All member genes

	x	abs
CDC45	1783	3490
DNA2	3379	6486
FEN1	367	721
GINS1	7335	14342
GINS2	6909	13245
GINS3	6759	12937
GINS4	6560	12516
LIG1	6206	11811
MCM2	6755	12926
MCM3	4773	9054
MCM4	6635	12667
MCM5	6983	13415
MCM6	6787	12996
MCM7	2514	4863
MCM8	4587	8710
PCNA	6523	12452
POLA1	4949	9387
POLA2	6695	12805
POLD1	5832	11069
POLD2	4930	9350
POLD3	4459	8459
POLD4	-3285	6907
PRIM1	6962	13355
PRIM2	6599	12596
RFC1	-4980	10506
RFC2	3878	7371
RFC3	5349	10111
RFC4	4683	8885
RFC5	4385	8324
RPA1	-5008	10563
RPA2	6961	13354
RPA3	6375	12149

---

---

Complement cascade

Complement cascade

metric	value
setSize	35
pMANOVA	3.47e-12
p.adjustMANOVA	1.94e-10
s.dist	0.695
s.x	0.498
s.abs	0.485
p.x	3.48e-07
p.abs	6.84e-07

Top 20 genes

Gene	x	abs
SERPING1	7387	14532
C1S	7360	14430
C3	7357	14417
CFB	7350	14394
C4A	7346	14381
C8B	7343	14372
C4B	7286	14173
C8A	7235	14042
C5	7218	14003
C1R	7201	13954
MBL2	6911	13247
VTN	6910	13246
CFI	6891	13206
C5AR1	6719	12862
C6	6620	12636
PROS1	6053	11519
MASP2	5751	10923
CLU	5647	10723
CFD	5558	10570
C4BPA	5221	9865

Click HERE to show all gene set members

All member genes

	x	abs
C1R	7201	13954
C1S	7360	14430
C2	4264	8098
C3	7357	14417
C4A	7346	14381
C4B	7286	14173
C4BPA	5221	9865
C4BPB	-6787	14006
C5	7218	14003
C5AR1	6719	12862
C5AR2	3489	6671
C6	6620	12636
C7	4745	9004
C8A	7235	14042
C8B	7343	14372
C8G	-2213	4585
CD19	-472	954
CD46	5036	9531
CD55	-6517	13575
CD59	-3245	6818
CFB	7350	14394
CFD	5558	10570
CFI	6891	13206
CLU	5647	10723
COLEC11	-5996	12595
CPB2	4337	8234
CPN1	4039	7658
CPN2	-110	221
F2	635	1246
MASP1	-6062	12716
MASP2	5751	10923
MBL2	6911	13247
PROS1	6053	11519
SERPING1	7387	14532
VTN	6910	13246

---

---

Developmental Biology

Developmental Biology

metric	value
setSize	677
pMANOVA	3.52e-12
p.adjustMANOVA	1.94e-10
s.dist	0.166
s.x	-0.163
s.abs	0.0281
p.x	6e-13
p.abs	0.217

Top 20 genes

Gene	x	abs
GFI1	-7110	14489
KLF4	-7093	14463
VASP	-7075	14437
ABLIM1	-7055	14411
RUNX1	-7020	14359
RPL36AL	-6981	14313
ETF1	-6952	14268
RNPS1	-6938	14245
TGFB1	-6934	14241
ARHGEF28	-6925	14232
SHC1	-6910	14209
MAML1	-6891	14179
MET	-6878	14159
RANBP9	-6871	14151
EPHA2	-6857	14124
ACTG1	-6841	14090
GSPT1	-6825	14070
ANK2	-6778	13993
SEMA6A	-6761	13971
RHOC	-6747	13943

Click HERE to show all gene set members

All member genes

	x	abs
ABL1	2023	3944
ABL2	-3020	6296
ABLIM1	-7055	14411
ABLIM2	6389	12183
ABLIM3	2675	5174
ACTB	-5057	10683
ACTG1	-6841	14090
ACTR2	1435	2855
ACTR3	-5296	11186
ACVR1B	4400	8345
ACVR2A	775	1545
ACVR2B	931	1830
ADAM10	-2671	5549
ADAM11	-1647	3359
ADAM22	1805	3543
ADGRG6	-428	867
ADGRV1	6861	13152
AGAP2	4399	8342
AGRN	-2369	4911
AJUBA	6013	11454
AKAP5	3035	5848
AKT1	-2958	6160
AKT2	-1946	3993
ALCAM	3171	6109
ANGPTL4	6953	13342
ANK1	-4656	9901
ANK2	-6778	13993
ANK3	303	591
AP2A1	-1902	3903
AP2A2	-3499	7391
AP2B1	2029	3955
AP2M1	-4603	9787
AP2S1	-2922	6073
APH1A	619	1209
APH1B	6168	11741
ARHGAP35	-6446	13445
ARHGAP39	-6303	13184
ARHGEF11	-5260	11110
ARHGEF12	-1086	2216
ARHGEF28	-6925	14232
ARHGEF7	-2913	6055
ARPC1A	3022	5822
ARPC1B	-4429	9372
ARPC2	-2209	4575
ARPC3	3797	7237
ARPC4	-6094	12778
ARPC5	-1511	3073
ARTN	973	1918
ASH2L	4729	8974
BNIP2	-5239	11072
CACNA1D	-5676	11949
CACNA1H	-3915	8269
CACNB1	2967	5703
CACNB3	3735	7109
CACNB4	1983	3874
CACNG4	-3785	7988
CACNG8	1174	2305
CAP1	-4085	8634
CAP2	-2694	5594
CAPN1	-5850	12305
CAPNS1	-4414	9343
CARM1	3517	6725
CASC3	-5986	12577
CBFB	-6381	13329
CCNC	-2471	5121
CCND3	-2677	5565
CD24	5327	10076
CD36	5264	9953
CDC42	-2172	4489
CDH15	-2166	4482
CDH2	-2339	4845
CDK19	-1471	2984
CDK2	4114	7809
CDK4	-5064	10698
CDK5	-1352	2721
CDK5R1	-157	326
CDK8	-4276	9040
CDKN1A	-3580	7569
CDON	2669	5163
CEBPA	3000	5769
CEBPB	-1129	2300
CEBPD	6867	13165
CFL1	-5737	12075
CHD9	-4634	9842
CLASP1	1561	3071
CLASP2	-4246	8977
CLTA	-6439	13432
CLTB	-6064	12719
CLTC	-6220	13017
CLTCL1	6404	12210
CNOT6	732	1450
CNTN2	200	389
CNTNAP1	7239	14053
COL4A5	6694	12804
COL6A1	7322	14284
COL6A2	3222	6195
COL6A3	2085	4068
COL9A2	7348	14389
COL9A3	7151	13817
CREB1	474	935
CREBBP	-3888	8214
CSF3R	7351	14395
CSNK2A1	-5040	10637
CSNK2A2	-4546	9641
CSNK2B	4415	8368
CSTA	2890	5576
CTCF	4990	9457
CTNNA1	-5558	11711
CTNNB1	3272	6288
CUL2	359	703
CYP51A1	6741	12901
DAG1	-2174	4498
DEK	4581	8696
DKK1	4410	8362
DLG1	-3865	8171
DLG3	5168	9763
DLG4	5108	9664
DNM1	6505	12417
DNM2	-6535	13597
DOCK1	3540	6760
DOK1	4072	7718
DOK4	-2697	5609
DOK6	-2987	6228
DPPA4	3619	6901
DPYSL2	-6519	13578
DPYSL4	1531	3019
DRAP1	2970	5707
DSC2	-2349	4865
DSC3	-202	413
DSCAML1	-2830	5885
DSG2	-4228	8936
DSP	-4746	10069
E2F1	7096	13694
EED	2369	4581
EFNA1	-5830	12263
EFNA2	1735	3403
EFNA3	-1228	2484
EFNA4	3658	6973
EFNB1	3480	6658
EFNB2	-3470	7322
EFNB3	3419	6539
EGFR	-5383	11344
EGR2	-3207	6724
EIF4A3	1154	2270
EIF4G1	-5901	12400
ELOB	-3004	6272
ELOC	645	1265
ENAH	-3139	6582
EP300	-6470	13485
EPAS1	-4915	10387
EPHA1	4960	9410
EPHA10	1725	3385
EPHA2	-6857	14124
EPHB1	-5141	10858
EPHB4	-4379	9264
ERBB2	5534	10533
ETF1	-6952	14268
EVL	2467	4757
EVPL	7038	13528
EZH2	-5631	11860
EZR	-4464	9453
FAM120B	4955	9402
FARP2	3688	7020
FAU	-4990	10520
FES	5506	10476
FGFR1	-6191	12960
FLRT3	7184	13907
FOXA2	-1563	3171
FOXA3	2431	4694
FOXO1	5418	10275
FOXO3	2282	4415
FOXP1	-4141	8747
FRS2	-3790	8007
FURIN	-6683	13851
FYN	1937	3783
GAB1	1575	3105
GAB2	-4127	8722
GATA2	-1286	2587
GATA4	-6369	13306
GATA6	2495	4816
GDF1	5042	9539
GDNF	-3969	8396
GFI1	-7110	14489
GFRA3	4393	8334
GIT1	-5582	11767
GJB1	6678	12765
GPC1	5178	9776
GRB10	-5504	11598
GRB2	-3047	6346
GRB7	-4006	8477
GRIN1	-442	902
GRIN2B	1330	2648
GSK3B	-5101	10767
GSPT1	-6825	14070
H2AFX	5356	10131
HDAC2	-338	693
HDAC3	38	84
HELZ2	4786	9086
HES1	7265	14121
HHEX	922	1804
HIF3A	4444	8437
HMGCR	7355	14408
HNF1A	783	1559
HNF1B	912	1782
HNF4A	-121	248
HNF4G	-890	1815
HOXA2	2735	5280
HOXA3	6669	12744
HOXA4	-5235	11064
HOXD1	1160	2279
HRAS	-5543	11673
HSP90AA1	-1030	2096
HSP90AB1	-4426	9363
HSPA8	-4654	9895
IL6R	-4943	10440
IRS2	-5461	11497
ITGA1	5152	9740
ITGA10	-6466	13478
ITGA2	-6205	12988
ITGA2B	-688	1391
ITGA5	587	1149
ITGAV	-4312	9120
ITGB1	-4145	8760
ITSN1	159	311
JUN	-2934	6103
JUP	2314	4478
KALRN	-408	828
KAT2A	5077	9597
KAT2B	-4792	10158
KAZN	-6374	13318
KDM6A	-6150	12878
KIF4A	6056	11524
KLF4	-7093	14463
KLF5	-6373	13317
KMT2A	-3225	6772
KMT2C	-6514	13569
KMT2D	-6260	13087
KRAS	-2044	4210
KRT10	2866	5529
KRT15	1181	2318
KRT17	-6225	13030
KRT18	-6682	13848
KRT19	-4417	9346
KRT23	-4907	10366
KRT8	-6499	13540
KRT80	-4809	10197
L1CAM	-904	1841
LAMA1	1285	2553
LAMB1	3783	7198
LAMC1	-1300	2611
LDB1	1882	3689
LEFTY2	5686	10803
LIMK1	1565	3082
LIMK2	6394	12193
LYN	-3038	6328
LYPLA2	-4095	8653
MAFA	-561	1146
MAGOH	-969	1976
MAGOHB	5814	11039
MAML1	-6891	14179
MAML2	6847	13122
MAP2K1	-4120	8704
MAP2K2	-6087	12766
MAP2K6	-2351	4868
MAPK1	-5066	10705
MAPK11	251	492
MAPK12	-5538	11663
MAPK13	-1875	3846
MAPK14	2269	4391
MAPK3	6640	12684
MAPK7	-4382	9270
MAPK8	-700	1418
MBP	2888	5570
MED1	-5451	11468
MED10	-1134	2313
MED11	4574	8686
MED12	3501	6690
MED13	-5289	11168
MED13L	-4184	8847
MED14	-1453	2943
MED15	-4756	10099
MED16	610	1198
MED17	-4637	9850
MED18	-3198	6710
MED19	-1350	2717
MED20	5621	10676
MED21	-723	1457
MED22	6131	11676
MED23	2950	5679
MED24	-715	1445
MED25	1246	2466
MED26	-4882	10313
MED27	-2745	5729
MED28	2239	4339
MED29	6433	12264
MED30	5637	10702
MED31	341	657
MED4	2904	5601
MED6	-2003	4113
MED7	5750	10922
MED8	157	308
MED9	4847	9189
MEF2A	-3308	6959
MEF2B	4564	8661
MEF2D	-5995	12594
MEIS1	5510	10482
MET	-6878	14159
MMP2	-4677	9932
MPZ	7386	14523
MSI1	4326	8215
MYC	1892	3708
MYH10	2558	4942
MYH11	1015	1998
MYH14	5492	10431
MYH9	-4726	10036
MYL12A	-3398	7159
MYL12B	-6653	13785
MYL6	-6380	13325
MYL9	2704	5218
MYO10	-5290	11171
MYO9B	-5920	12432
NAB1	765	1529
NAB2	-6372	13315
NANOG	1164	2288
NCBP1	-2151	4458
NCBP2	6823	13081
NCK1	1525	3010
NCK2	-3916	8271
NCOA1	-4665	9914
NCOA2	4780	9072
NCOA3	-2326	4825
NCOA6	-6745	13941
NCOR1	-4374	9256
NCOR2	-4409	9331
NCSTN	-554	1137
NEO1	4016	7629
NFKB1	-3507	7409
NGEF	7064	13605
NOTCH1	-3923	8281
NR2F2	-4332	9167
NR5A1	-4679	9936
NR5A2	-5547	11680
NR6A1	-3646	7721
NRAS	2310	4465
NRCAM	-3815	8057
NRP1	1353	2695
NRP2	-5313	11212
NRTN	3870	7357
NTN4	-1999	4099
NUMB	-5224	11036
ONECUT1	5291	10006
ONECUT3	1186	2331
PABPC1	-3543	7490
PAGR1	1634	3220
PAK1	1031	2021
PAK2	-4957	10458
PAK4	-5359	11295
PAX6	-478	967
PAXIP1	-4383	9272
PBX1	827	1631
PCGF2	-5881	12369
PCK1	6525	12455
PCSK6	5326	10075
PDLIM7	-2636	5473
PDX1	5812	11037
PERP	4630	8783
PFN1	-6285	13146
PFN2	6877	13179
PIAS2	388	761
PIK3CA	-2813	5849
PIK3CB	-2588	5379
PIK3CD	-4759	10102
PIK3R1	-4376	9259
PIK3R2	-1355	2728
PIK3R3	-2279	4734
PIP5K1C	-3229	6778
PITPNA	-5591	11779
PKLR	7311	14260
PKNOX1	-3036	6325
PKP2	1490	2944
PKP3	204	401
PKP4	-1800	3674
PLCG1	2511	4855
PLIN1	3775	7186
PLXNA1	-1050	2146
PLXNA2	-3814	8056
PLXNA3	-6318	13213
PLXNB1	-1046	2132
PLXNB3	-3778	7967
PLXNC1	4319	8196
PLXND1	-5686	11963
PML	1051	2057
PMP22	7297	14203
POLR2A	2705	5219
POLR2B	-3699	7815
POLR2C	-3425	7212
POLR2D	2418	4674
POLR2E	-4667	9916
POLR2F	-5283	11158
POLR2G	2003	3910
POLR2H	-3593	7590
POLR2I	4594	8717
POLR2J	-603	1234
POLR2K	5962	11350
POLR2L	-5471	11530
POU5F1	-4823	10220
PPARA	-6722	13906
PPARG	-3168	6636
PPARGC1A	-5869	12350
PPL	-3149	6600
PPP3CB	-4060	8574
PRKACA	1736	3407
PRKACB	-1429	2885
PRKAR2A	-860	1753
PRKCA	2439	4709
PRNP	-6115	12816
PRSS8	7354	14402
PRX	-2432	5042
PSEN1	-4938	10427
PSEN2	-2559	5310
PSENEN	-2327	4828
PSMA1	-5730	12052
PSMA2	-5801	12203
PSMA3	-3078	6422
PSMA4	-4211	8902
PSMA5	-2715	5657
PSMA6	-126	261
PSMA7	-892	1820
PSMB1	1054	2062
PSMB10	423	838
PSMB2	1876	3678
PSMB3	-1915	3928
PSMB4	-1144	2330
PSMB5	-742	1484
PSMB6	-4888	10326
PSMB7	-4372	9253
PSMB9	5491	10430
PSMC1	-5564	11724
PSMC2	-2389	4948
PSMC3	-1509	3070
PSMC4	-4808	10196
PSMC5	-4091	8646
PSMC6	-4878	10307
PSMD1	-5351	11280
PSMD10	4933	9356
PSMD11	-432	879
PSMD12	4303	8163
PSMD13	-2577	5353
PSMD14	5974	11371
PSMD2	-6435	13423
PSMD3	-5535	11655
PSMD4	4567	8670
PSMD5	5116	9676
PSMD6	-5951	12502
PSMD7	4942	9371
PSMD8	-2928	6091
PSMD9	-4638	9853
PSME1	-2348	4861
PSME2	-5481	11555
PSME3	-3813	8052
PSME4	-6450	13450
PSMF1	-6663	13810
PSPN	-5177	10939
PTK2	-4346	9198
PTPN11	-867	1770
PTPRA	815	1606
RAC1	44	95
RANBP9	-6871	14151
RAP1GAP	-4998	10531
RARA	-6269	13109
RARG	173	335
RASA1	2559	4950
RBBP4	-3297	6938
RBBP5	-101	204
RBBP7	5134	9712
RBM8A	-1583	3215
RBPJ	4794	9099
RBX1	-3714	7850
RDX	1011	1989
RELA	-2632	5468
RELN	-662	1347
RGMA	3210	6178
RGMB	1321	2630
RHOA	-5294	11182
RHOB	6064	11537
RHOC	-6747	13943
RND1	-1410	2828
RNPS1	-6938	14245
ROBO1	-5577	11752
ROBO3	4691	8903
ROCK1	-3594	7591
ROCK2	-2772	5775
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS6KA1	-3857	8159
RPS6KA2	-1149	2339
RPS6KA3	-3030	6316
RPS6KA4	731	1447
RPS6KA5	3086	5949
RPS6KA6	3918	7442
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
RRAS	-1578	3199
RUNX1	-7020	14359
RXRA	-4073	8607
SALL1	1265	2511
SALL4	6934	13298
SCD5	3592	6855
SCN11A	-295	607
SCN1A	7327	14299
SCN1B	2398	4633
SCN2A	-6712	13891
SCN3B	2499	4826
SCN8A	249	488
SCN9A	3533	6751
SDC2	147	289
SDCBP	-1822	3724
SEM1	-3130	6566
SEMA3A	4001	7600
SEMA4D	6479	12347
SEMA6A	-6761	13971
SEMA7A	-3299	6944
SH3KBP1	-917	1864
SHANK3	935	1838
SHC1	-6910	14209
SHC3	-3782	7979
SHTN1	547	1074
SIAH1	-3347	7045
SIAH2	-6666	13819
SLC2A2	7259	14109
SLC2A4	1030	2019
SLIT1	886	1741
SMAD2	-4087	8639
SMAD3	-6145	12871
SMAD4	2742	5290
SMARCA4	-3226	6773
SMARCD3	2305	4455
SNW1	-5581	11762
SOS1	-950	1928
SOS2	-5417	11402
SOX9	7103	13716
SPAG9	-5897	12395
SPINK9	2709	5227
SPTAN1	2385	4610
SPTBN1	-4901	10356
SPTBN2	3883	7379
SRC	3962	7516
SREBF1	-3554	7517
SREBF2	7304	14223
SRGAP1	-1796	3662
SRGAP2	-1779	3627
SRGAP3	6775	12970
SRY	5473	10390
ST14	1967	3840
STAT3	4253	8078
STX1A	-2377	4922
STX1B	1841	3612
SUZ12	346	664
TBL1X	-1621	3308
TBL1XR1	1404	2795
TCF12	-3164	6626
TCF3	-1396	2805
TDGF1	-5711	12019
TEAD1	6440	12277
TFDP1	-2579	5361
TFDP2	4856	9210
TGFB1	-6934	14241
TGM1	-2621	5448
TGS1	2148	4181
THRAP3	-3489	7364
TIAM1	4452	8451
TLN1	-6146	12872
TRIO	-5341	11264
TRPC1	3602	6877
TSC22D1	4059	7699
UBA52	-5068	10707
UBB	-4263	9013
UBC	779	1551
UNC5B	-6252	13071
UPF2	-3830	8093
UPF3A	-6189	12957
UPF3B	2326	4503
USP33	1924	3761
UTRN	-4105	8674
VASP	-7075	14437
VAV2	2817	5425
VAV3	-4642	9861
VLDLR	3001	5770
WASL	-6543	13611
WDR5	2561	4953
WT1	114	225
WWTR1	-271	555
YAP1	2171	4225
YES1	-1340	2690
YY1	-5214	11015
ZFPM2	1391	2765
ZNF335	-1966	4037
ZNF638	1329	2646
ZSWIM8	-5267	11127

---

---

Translation

Translation

metric	value
setSize	270
pMANOVA	5.7e-12
p.adjustMANOVA	3.02e-10
s.dist	0.254
s.x	-0.253
s.abs	-0.0224
p.x	9.51e-13
p.abs	0.529

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
AARS2	5743	10908
AIMP1	1790	3508
AIMP2	1067	2099
APEH	4698	8922
AURKAIP1	-5100	10765
CARS2	2078	4056
CHCHD1	1058	2069
DAP3	972	1917
DARS2	2466	4756
DDOST	-6429	13410
EARS2	1253	2477
EEF1A1	-4138	8740
EEF1A1P5	-1745	3558
EEF1A2	553	1086
EEF1B2	-4836	10243
EEF1D	-5115	10800
EEF1E1	-4013	8489
EEF1G	-3612	7628
EEF2	-5049	10659
EIF1AX	-274	563
EIF2B1	-143	293
EIF2B2	-4811	10200
EIF2B3	5203	9835
EIF2B4	437	862
EIF2B5	-4838	10248
EIF2S1	-5190	10961
EIF2S2	-4458	9437
EIF2S3	-3669	7757
EIF3A	-6965	14290
EIF3B	-5127	10829
EIF3C	-374	764
EIF3D	-3740	7889
EIF3E	3244	6234
EIF3F	-893	1821
EIF3G	-4724	10029
EIF3H	899	1763
EIF3I	-5279	11151
EIF3J	-4539	9629
EIF3K	-2206	4569
EIF3L	-2407	4991
EIF3M	-4358	9224
EIF4A1	-6995	14329
EIF4A2	5593	10631
EIF4B	-5898	12396
EIF4E	2473	4766
EIF4EBP1	4858	9212
EIF4G1	-5901	12400
EIF4H	-5055	10679
EIF5	-6065	12721
EIF5B	3318	6386
ERAL1	2351	4546
ETF1	-6952	14268
FARS2	1328	2645
FARSA	-2976	6205
FARSB	3269	6282
FAU	-4990	10520
GADD45GIP1	-3917	8274
GFM1	-2827	5882
GFM2	-2567	5337
GSPT1	-6825	14070
HARS2	5687	10804
IARS2	-1767	3601
LARS2	6133	11681
MARS2	1957	3819
MRPL1	5865	11138
MRPL10	3731	7100
MRPL11	4075	7726
MRPL12	4261	8090
MRPL13	482	955
MRPL14	-4864	10287
MRPL15	1406	2798
MRPL16	5878	11164
MRPL17	5943	11317
MRPL18	-882	1806
MRPL19	96	185
MRPL2	6122	11658
MRPL20	773	1542
MRPL21	2518	4873
MRPL22	-2025	4161
MRPL23	-4800	10172
MRPL24	6982	13414
MRPL27	2747	5301
MRPL28	1039	2037
MRPL3	-5054	10675
MRPL30	5960	11343
MRPL32	-4532	9619
MRPL33	-4189	8854
MRPL34	-4611	9796
MRPL35	-4563	9685
MRPL36	-2957	6159
MRPL37	-2997	6255
MRPL38	-5234	11062
MRPL39	-2415	5007
MRPL4	-1923	3949
MRPL40	-473	956
MRPL41	-4594	9760
MRPL42	5341	10095
MRPL43	4791	9092
MRPL44	-4094	8651
MRPL46	-4455	9431
MRPL47	-4976	10494
MRPL48	-2613	5438
MRPL49	4062	7704
MRPL50	-402	818
MRPL51	-4467	9463
MRPL52	1657	3259
MRPL53	-1391	2796
MRPL54	-3013	6283
MRPL55	5826	11058
MRPL57	-2716	5658
MRPL58	1346	2678
MRPL9	-726	1463
MRPS10	-474	959
MRPS11	-2271	4718
MRPS12	-5083	10736
MRPS14	785	1561
MRPS15	-5376	11322
MRPS16	5883	11175
MRPS17	895	1758
MRPS18A	-532	1085
MRPS18B	-3346	7044
MRPS18C	-4493	9522
MRPS2	-5145	10865
MRPS21	4888	9271
MRPS22	-3909	8259
MRPS23	-2664	5535
MRPS24	-4327	9158
MRPS25	7089	13672
MRPS26	3245	6236
MRPS27	2381	4604
MRPS28	-2470	5120
MRPS30	-1657	3380
MRPS31	6190	11782
MRPS33	4704	8930
MRPS34	-2704	5623
MRPS35	-1461	2963
MRPS36	-3292	6924
MRPS5	787	1563
MRPS6	-5687	11965
MRPS7	1777	3479
MRPS9	-1007	2061
MRRF	-2721	5669
MTFMT	3156	6084
MTIF2	664	1307
MTIF3	-173	355
MTRF1L	-6400	13369
N6AMT1	7144	13806
NARS2	2113	4126
OXA1L	2372	4586
PABPC1	-3543	7490
PARS2	7123	13767
PPA1	-1553	3152
PPA2	2403	4640
PTCD3	1514	2990
RARS2	5085	9611
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPN1	-7013	14350
RPN2	-6193	12964
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
SARS2	-521	1066
SEC11A	-3046	6345
SEC11C	-6991	14325
SEC61A1	-7030	14374
SEC61A2	-1397	2808
SEC61B	-6958	14278
SEC61G	-4052	8561
SPCS1	2416	4672
SPCS2	-5930	12458
SPCS3	-6781	13996
SRP14	-5938	12470
SRP19	-6363	13297
SRP54	-1969	4041
SRP68	-6420	13394
SRP72	-5526	11640
SRP9	5604	10650
SRPRA	-4802	10175
SRPRB	-6893	14181
SSR1	-6907	14205
SSR2	-6759	13968
SSR3	-6928	14235
SSR4	-7004	14338
TARS2	2575	4978
TRAM1	-6997	14331
TRMT112	-3869	8181
TSFM	-1098	2236
TUFM	-3458	7286
UBA52	-5068	10707
VARS2	-1827	3738
WARS2	4080	7734
YARS2	-645	1313

---

---

Eukaryotic Translation Elongation

Eukaryotic Translation Elongation

metric	value
setSize	91
pMANOVA	6.39e-12
p.adjustMANOVA	3.17e-10
s.dist	0.43
s.x	-0.407
s.abs	-0.14
p.x	2.06e-11
p.abs	0.0212

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
EEF1A1	-4138	8740
EEF1A1P5	-1745	3558
EEF1A2	553	1086
EEF1B2	-4836	10243
EEF1D	-5115	10800
EEF1G	-3612	7628
EEF2	-5049	10659
FAU	-4990	10520
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
UBA52	-5068	10707

---

---

Regulation of expression of SLITs and ROBOs

Regulation of expression of SLITs and ROBOs

metric	value
setSize	157
pMANOVA	6.44e-12
p.adjustMANOVA	3.17e-10
s.dist	0.33
s.x	-0.325
s.abs	-0.0556
p.x	2.15e-12
p.abs	0.23

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
CASC3	-5986	12577
COL4A5	6694	12804
CUL2	359	703
DAG1	-2174	4498
EIF4A3	1154	2270
EIF4G1	-5901	12400
ELOB	-3004	6272
ELOC	645	1265
ETF1	-6952	14268
FAU	-4990	10520
GSPT1	-6825	14070
HOXA2	2735	5280
LDB1	1882	3689
MAGOH	-969	1976
MAGOHB	5814	11039
MSI1	4326	8215
NCBP1	-2151	4458
NCBP2	6823	13081
PABPC1	-3543	7490
PSMA1	-5730	12052
PSMA2	-5801	12203
PSMA3	-3078	6422
PSMA4	-4211	8902
PSMA5	-2715	5657
PSMA6	-126	261
PSMA7	-892	1820
PSMB1	1054	2062
PSMB10	423	838
PSMB2	1876	3678
PSMB3	-1915	3928
PSMB4	-1144	2330
PSMB5	-742	1484
PSMB6	-4888	10326
PSMB7	-4372	9253
PSMB9	5491	10430
PSMC1	-5564	11724
PSMC2	-2389	4948
PSMC3	-1509	3070
PSMC4	-4808	10196
PSMC5	-4091	8646
PSMC6	-4878	10307
PSMD1	-5351	11280
PSMD10	4933	9356
PSMD11	-432	879
PSMD12	4303	8163
PSMD13	-2577	5353
PSMD14	5974	11371
PSMD2	-6435	13423
PSMD3	-5535	11655
PSMD4	4567	8670
PSMD5	5116	9676
PSMD6	-5951	12502
PSMD7	4942	9371
PSMD8	-2928	6091
PSMD9	-4638	9853
PSME1	-2348	4861
PSME2	-5481	11555
PSME3	-3813	8052
PSME4	-6450	13450
PSMF1	-6663	13810
RBM8A	-1583	3215
RBX1	-3714	7850
RNPS1	-6938	14245
ROBO1	-5577	11752
ROBO3	4691	8903
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
SEM1	-3130	6566
SLIT1	886	1741
UBA52	-5068	10707
UBB	-4263	9013
UBC	779	1551
UPF2	-3830	8093
UPF3A	-6189	12957
UPF3B	2326	4503
USP33	1924	3761
ZSWIM8	-5267	11127

---

---

Signaling by ROBO receptors

Signaling by ROBO receptors

metric	value
setSize	193
pMANOVA	8.7e-12
p.adjustMANOVA	4.13e-10
s.dist	0.296
s.x	-0.293
s.abs	-0.0467
p.x	2.58e-12
p.abs	0.264

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
ABL1	2023	3944
ABL2	-3020	6296
AKAP5	3035	5848
ARHGAP39	-6303	13184
CAP1	-4085	8634
CAP2	-2694	5594
CASC3	-5986	12577
CDC42	-2172	4489
CLASP1	1561	3071
CLASP2	-4246	8977
COL4A5	6694	12804
CUL2	359	703
DAG1	-2174	4498
EIF4A3	1154	2270
EIF4G1	-5901	12400
ELOB	-3004	6272
ELOC	645	1265
ENAH	-3139	6582
ETF1	-6952	14268
EVL	2467	4757
FAU	-4990	10520
FLRT3	7184	13907
GPC1	5178	9776
GSPT1	-6825	14070
HOXA2	2735	5280
LDB1	1882	3689
MAGOH	-969	1976
MAGOHB	5814	11039
MSI1	4326	8215
MYO9B	-5920	12432
NCBP1	-2151	4458
NCBP2	6823	13081
NCK1	1525	3010
NCK2	-3916	8271
NRP1	1353	2695
PABPC1	-3543	7490
PAK1	1031	2021
PAK2	-4957	10458
PAK4	-5359	11295
PFN1	-6285	13146
PFN2	6877	13179
PPP3CB	-4060	8574
PRKACA	1736	3407
PRKACB	-1429	2885
PRKAR2A	-860	1753
PRKCA	2439	4709
PSMA1	-5730	12052
PSMA2	-5801	12203
PSMA3	-3078	6422
PSMA4	-4211	8902
PSMA5	-2715	5657
PSMA6	-126	261
PSMA7	-892	1820
PSMB1	1054	2062
PSMB10	423	838
PSMB2	1876	3678
PSMB3	-1915	3928
PSMB4	-1144	2330
PSMB5	-742	1484
PSMB6	-4888	10326
PSMB7	-4372	9253
PSMB9	5491	10430
PSMC1	-5564	11724
PSMC2	-2389	4948
PSMC3	-1509	3070
PSMC4	-4808	10196
PSMC5	-4091	8646
PSMC6	-4878	10307
PSMD1	-5351	11280
PSMD10	4933	9356
PSMD11	-432	879
PSMD12	4303	8163
PSMD13	-2577	5353
PSMD14	5974	11371
PSMD2	-6435	13423
PSMD3	-5535	11655
PSMD4	4567	8670
PSMD5	5116	9676
PSMD6	-5951	12502
PSMD7	4942	9371
PSMD8	-2928	6091
PSMD9	-4638	9853
PSME1	-2348	4861
PSME2	-5481	11555
PSME3	-3813	8052
PSME4	-6450	13450
PSMF1	-6663	13810
RAC1	44	95
RBM8A	-1583	3215
RBX1	-3714	7850
RHOA	-5294	11182
RNPS1	-6938	14245
ROBO1	-5577	11752
ROBO3	4691	8903
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
SEM1	-3130	6566
SLIT1	886	1741
SOS1	-950	1928
SOS2	-5417	11402
SRC	3962	7516
SRGAP1	-1796	3662
SRGAP2	-1779	3627
SRGAP3	6775	12970
UBA52	-5068	10707
UBB	-4263	9013
UBC	779	1551
UPF2	-3830	8093
UPF3A	-6189	12957
UPF3B	2326	4503
USP33	1924	3761
VASP	-7075	14437
ZSWIM8	-5267	11127

---

---

Diseases of signal transduction by growth factor receptors and second messengers

Diseases of signal transduction by growth factor receptors and second messengers

metric	value
setSize	361
pMANOVA	1.36e-11
p.adjustMANOVA	6.24e-10
s.dist	0.219
s.x	-0.214
s.abs	0.0498
p.x	3.78e-12
p.abs	0.105

Top 20 genes

Gene	x	abs
SEL1L	-7124	14508
SYVN1	-7108	14485
ARRB1	-7062	14420
DERL2	-7046	14399
EIF2AK3	-7028	14371
SQSTM1	-7010	14347
OS9	-6986	14320
PEBP1	-6972	14300
PIK3AP1	-6957	14273
JAG1	-6948	14259
TGFB1	-6934	14241
SHC1	-6910	14209
MAML1	-6891	14179
MET	-6878	14159
PDGFRB	-6820	14062
VCP	-6720	13902
PSMF1	-6663	13810
RRBP1	-6551	13627
EP300	-6470	13485
PSME4	-6450	13450

Click HERE to show all gene set members

All member genes

	x	abs
ADAM10	-2671	5549
ADAM17	-5836	12276
AGGF1	3135	6035
AGK	2062	4016
AGTRAP	5793	11004
AKAP9	5113	9671
AKT1	-2958	6160
AKT1S1	-5990	12584
AKT2	-1946	3993
AMER1	5007	9484
AP3B1	13	31
APC	-1818	3716
APH1A	619	1209
APH1B	6168	11741
ARAF	-5242	11076
AREG	-4847	10258
ARRB1	-7062	14420
ARRB2	-3248	6824
ATG7	5453	10354
ATIC	-520	1065
AXIN1	-4215	8908
BAD	-6118	12822
BAG4	4019	7633
BCL2L1	-6349	13271
BCL2L11	-3834	8099
BCR	-2502	5190
BIRC6	-3068	6387
BRAF	-4749	10077
BRAP	1211	2384
CALM1	-655	1340
CAMK2A	4566	8669
CAMK2D	1711	3358
CAMK2G	2145	4176
CASP9	-5247	11084
CBL	-5708	12008
CCNC	-2471	5121
CD19	-472	954
CDC37	-5178	10941
CDK8	-4276	9040
CDKN1A	-3580	7569
CDKN1B	-786	1590
CEBPB	-1129	2300
CHUK	-3364	7086
CLCN6	3165	6094
CLTC	-6220	13017
CNKSR1	3649	6956
CNTRL	6358	12110
CPSF6	-4789	10151
CREB1	474	935
CREBBP	-3888	8214
CSK	-4113	8692
CSNK1A1	-5349	11277
CTBP1	-41	73
CTBP2	-4982	10508
CTNNB1	3272	6288
CUL1	-4129	8725
CUX1	-1665	3398
DCTN1	-1635	3338
DERL2	-7046	14399
DKK1	4410	8362
DKK4	-5490	11570
DUSP10	-5271	11134
DUSP16	-1750	3571
DUSP6	-3376	7113
DUSP7	-3870	8185
DUSP8	4879	9251
DUSP9	-284	580
EEF1G	-3612	7628
EGFR	-5383	11344
EIF2AK3	-7028	14371
EML4	27	66
EP300	-6470	13485
ERBB2	5534	10533
ERBB3	4249	8072
ERBIN	-2316	4809
EREG	3467	6635
ERLEC1	-6168	12918
ERLIN2	5405	10235
ESR2	3316	6378
ETV6	-1588	3225
FAM114A2	6340	12078
FBXW7	-2564	5325
FGA	7336	14346
FGB	7226	14018
FGF17	-4015	8493
FGF23	2097	4091
FGF5	342	659
FGFR1	-6191	12960
FGFR1OP2	-6202	12984
FGFR2	6811	13048
FGFR3	-1195	2426
FGFR4	-2795	5810
FGG	6697	12809
FIP1L1	-5876	12362
FKBP1A	-5189	10960
FLT3LG	6000	11436
FN1	-3115	6525
FOXO1	5418	10275
FOXO3	2282	4415
FOXO4	-2077	4276
FRS2	-3790	8007
FRS3	2112	4125
FXR1	-4803	10176
FYN	1937	3783
FZD4	6534	12474
FZD5	4841	9179
FZD6	6312	12029
FZD8	2263	4376
GAB1	1575	3105
GAB2	-4127	8722
GCC2	-597	1225
GOLGA4	-4624	9822
GOLGB1	-3498	7386
GRB2	-3047	6346
GSK3A	-3684	7787
GSK3B	-5101	10767
GTF2F1	-3103	6481
GTF2F2	4556	8650
HBEGF	-4402	9320
HDAC1	-2676	5563
HDAC10	-1408	2826
HDAC11	1004	1970
HDAC2	-338	693
HDAC3	38	84
HDAC4	-1478	2998
HDAC5	-4034	8527
HDAC6	5953	11333
HDAC7	130	254
HDAC8	3835	7301
HES1	7265	14121
HEY1	-3864	8169
HHAT	4068	7712
HIP1	7319	14277
HRAS	-5543	11673
HSP90AA1	-1030	2096
IHH	-4252	8989
IQGAP1	-5663	11931
IRS1	3502	6691
IRS2	-5461	11497
ITGA2B	-688	1391
JAG1	-6948	14259
JAG2	-516	1048
JAK2	-2719	5664
JUNB	-3526	7447
KANK1	4837	9175
KAT2A	5077	9597
KAT2B	-4792	10158
KDM7A	-6055	12709
KIAA1549	-5776	12155
KIF5B	-5426	11419
KITLG	92	180
KLB	-3807	8045
KLC1	4611	8755
KRAS	-2044	4210
KREMEN1	364	715
KREMEN2	-791	1609
KSR1	-1	5
LCK	-6250	13069
LMNA	-3717	7854
LMO7	-1246	2512
LRP5	-2319	4812
LRP6	-4613	9800
LRRFIP1	-5477	11545
LYN	-3038	6328
MAML1	-6891	14179
MAML2	6847	13122
MAP2K1	-4120	8704
MAP2K2	-6087	12766
MAP3K11	-4272	9031
MAPK1	-5066	10705
MAPK3	6640	12684
MAPKAP1	-5936	12466
MARK3	-3996	8448
MDM2	-956	1942
MECP2	-4891	10331
MET	-6878	14159
MIB1	1650	3250
MIB2	-4356	9222
MLST8	1875	3677
MPRIP	-266	545
MRAS	5118	9679
MTOR	-3683	7785
MYC	1892	3708
MYH9	-4726	10036
MYO18A	3903	7411
NCBP1	-2151	4458
NCBP2	6823	13081
NCOR1	-4374	9256
NCOR2	-4409	9331
NCSTN	-554	1137
NEURL1B	3778	7190
NF1	1648	3245
NOTCH1	-3923	8281
NPM1	-2033	4183
NR4A1	3691	7026
NRAS	2310	4465
OS9	-6986	14320
PAPSS1	3746	7130
PDGFA	-2660	5524
PDGFB	6920	13263
PDGFRB	-6820	14062
PDPK1	399	782
PEBP1	-6972	14300
PHB	-4920	10399
PIK3AP1	-6957	14273
PIK3CA	-2813	5849
PIK3CB	-2588	5379
PIK3CD	-4759	10102
PIK3R1	-4376	9259
PIK3R2	-1355	2728
PIK3R3	-2279	4734
PIM1	-4092	8647
PLCG1	2511	4855
POLR2A	2705	5219
POLR2B	-3699	7815
POLR2C	-3425	7212
POLR2D	2418	4674
POLR2E	-4667	9916
POLR2F	-5283	11158
POLR2G	2003	3910
POLR2H	-3593	7590
POLR2I	4594	8717
POLR2J	-603	1234
POLR2K	5962	11350
POLR2L	-5471	11530
PORCN	320	622
PPFIBP1	-3970	8397
PPM1B	-5398	11375
PPP1CB	-3630	7685
PPP1CC	-3392	7149
PPP2CA	-5168	10917
PPP2CB	-4523	9606
PPP2R1A	-4744	10064
PPP2R1B	4614	8759
PPP2R5A	-5740	12088
PPP2R5B	-5131	10834
PPP2R5C	2743	5293
PPP2R5D	-2117	4385
PPP2R5E	283	554
PRKAR1A	4	6
PRR5	-2094	4323
PSEN1	-4938	10427
PSEN2	-2559	5310
PSENEN	-2327	4828
PSMA1	-5730	12052
PSMA2	-5801	12203
PSMA3	-3078	6422
PSMA4	-4211	8902
PSMA5	-2715	5657
PSMA6	-126	261
PSMA7	-892	1820
PSMB1	1054	2062
PSMB10	423	838
PSMB2	1876	3678
PSMB3	-1915	3928
PSMB4	-1144	2330
PSMB5	-742	1484
PSMB6	-4888	10326
PSMB7	-4372	9253
PSMB9	5491	10430
PSMC1	-5564	11724
PSMC2	-2389	4948
PSMC3	-1509	3070
PSMC4	-4808	10196
PSMC5	-4091	8646
PSMC6	-4878	10307
PSMD1	-5351	11280
PSMD10	4933	9356
PSMD11	-432	879
PSMD12	4303	8163
PSMD13	-2577	5353
PSMD14	5974	11371
PSMD2	-6435	13423
PSMD3	-5535	11655
PSMD4	4567	8670
PSMD5	5116	9676
PSMD6	-5951	12502
PSMD7	4942	9371
PSMD8	-2928	6091
PSMD9	-4638	9853
PSME1	-2348	4861
PSME2	-5481	11555
PSME3	-3813	8052
PSME4	-6450	13450
PSMF1	-6663	13810
PTEN	-4721	10023
PTPN11	-867	1770
PTPN12	-5326	11236
QKI	-5427	11421
RAC1	44	95
RAF1	-5557	11708
RANBP2	-4	9
RAP1A	309	604
RAP1B	3577	6830
RBPJ	4794	9099
RBX1	-3714	7850
RHOG	-2756	5747
RICTOR	-2076	4274
RNF213	5584	10611
RNF43	1197	2353
RPS27A	-2773	5776
RPS6	-2681	5569
RPS6KB2	-3901	8241
RRBP1	-6551	13627
SEC31A	-5766	12138
SEL1L	-7124	14508
SEM1	-3130	6566
SHC1	-6910	14209
SHH	-3305	6953
SHOC2	-749	1499
SKP1	-544	1117
SMAD2	-4087	8639
SMAD3	-6145	12871
SMAD4	2742	5290
SND1	-6000	12607
SNW1	-5581	11762
SOS1	-950	1928
SPRED1	-2574	5348
SPRED2	-2862	5946
SPRED3	-3905	8248
SPTBN1	-4901	10356
SQSTM1	-7010	14347
SRC	3962	7516
STAT1	-5668	11938
STAT3	4253	8078
STAT5A	5288	10000
STAT5B	6572	12541
STRN	-5363	11300
SYVN1	-7108	14485
TBL1X	-1621	3308
TBL1XR1	1404	2795
TCF7L2	959	1893
TFG	-5336	11250
TGFA	-4511	9574
TGFB1	-6934	14241
TGFBR1	-2620	5447
TGFBR2	-3644	7714
TLN1	-6146	12872
TNKS	-4790	10153
TNKS2	-3213	6742
TPM3	-40	71
TPM4	-822	1674
TPR	565	1105
TRAK1	3646	6949
TRIM24	-4887	10323
TRIP11	-990	2024
TSC2	-2462	5097
UBA52	-5068	10707
UBB	-4263	9013
UBC	779	1551
VCL	4407	8357
VCP	-6720	13902
VWF	1933	3777
WDCP	6637	12675
WDR48	543	1063
YES1	-1340	2690
YWHAB	2082	4062
ZC3HAV1	4414	8366
ZC3HC1	5790	10991
ZFYVE9	1407	2801
ZMYM2	2755	5316

---

---

Response of EIF2AK4 (GCN2) to amino acid deficiency

Response of EIF2AK4 (GCN2) to amino acid deficiency

metric	value
setSize	98
pMANOVA	1.42e-11
p.adjustMANOVA	6.29e-10
s.dist	0.41
s.x	-0.4
s.abs	-0.0868
p.x	7.59e-12
p.abs	0.138

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
ASNS	6208	11814
ATF2	-6175	12933
ATF3	2488	4803
ATF4	-5664	11932
CEBPB	-1129	2300
CEBPG	-5987	12578
DDIT3	-7047	14401
EIF2AK4	-1455	2950
EIF2S1	-5190	10961
EIF2S2	-4458	9437
EIF2S3	-3669	7757
FAU	-4990	10520
GCN1	-4627	9826
IMPACT	4432	8414
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
TRIB3	-6798	14029
UBA52	-5068	10707

---

---

N-glycan trimming in the ER and Calnexin/Calreticulin cycle

N-glycan trimming in the ER and Calnexin/Calreticulin cycle

metric	value
setSize	34
pMANOVA	1.79e-11
p.adjustMANOVA	7.72e-10
s.dist	0.71
s.x	-0.574
s.abs	0.418
p.x	7.03e-09
p.abs	2.46e-05

Top 20 genes

Gene	x	abs
CALR	-7142	14529
SEL1L	-7124	14508
SYVN1	-7108	14485
EDEM1	-7103	14479
CANX	-7092	14462
PDIA3	-7086	14454
DERL2	-7046	14399
OS9	-6986	14320
UGGT1	-6954	14270
MLEC	-6902	14193
VCP	-6720	13902
RNF5	-6629	13745
DERL1	-6423	13398
RNF185	-6359	13291
RNF103	-6135	12848
PRKCSH	-5934	12463
PSMC1	-5564	11724
EDEM2	-5520	11628
UBXN1	-5450	11466
UBA52	-5068	10707

Click HERE to show all gene set members

All member genes

	x	abs
AMFR	-2698	5612
CALR	-7142	14529
CANX	-7092	14462
DERL1	-6423	13398
DERL2	-7046	14399
EDEM1	-7103	14479
EDEM2	-5520	11628
EDEM3	-1903	3904
ENGASE	6457	12309
GANAB	2813	5417
MAN1B1	-3561	7534
MLEC	-6902	14193
MOGS	-2275	4728
NGLY1	-2909	6049
OS9	-6986	14320
PDIA3	-7086	14454
PRKCSH	-5934	12463
PSMC1	-5564	11724
RAD23B	3141	6054
RNF103	-6135	12848
RNF139	-3064	6382
RNF185	-6359	13291
RNF5	-6629	13745
RPS27A	-2773	5776
SEL1L	-7124	14508
SYVN1	-7108	14485
TRIM13	1883	3695
UBA52	-5068	10707
UBB	-4263	9013
UBC	779	1551
UBXN1	-5450	11466
UGGT1	-6954	14270
UGGT2	1425	2839
VCP	-6720	13902

---

---

Viral mRNA Translation

Viral mRNA Translation

metric	value
setSize	86
pMANOVA	2.3e-11
p.adjustMANOVA	9.61e-10
s.dist	0.431
s.x	-0.41
s.abs	-0.135
p.x	5.18e-11
p.abs	0.0309

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
DNAJC3	-7131	14516
FAU	-4990	10520
GRSF1	-4747	10070
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
UBA52	-5068	10707

---

---

Post-translational protein modification

Post-translational protein modification

metric	value
setSize	1138
pMANOVA	2.54e-11
p.adjustMANOVA	1.03e-09
s.dist	0.127
s.x	-0.0967
s.abs	0.0822
p.x	5.82e-08
p.abs	4.03e-06

Top 20 genes

Gene	x	abs
CALR	-7142	14529
RAB17	-7135	14521
SEC24D	-7134	14520
DNAJC3	-7131	14516
HSP90B1	-7129	14514
SEL1L	-7124	14508
SELENOS	-7117	14498
SYVN1	-7108	14485
PDIA6	-7106	14482
EDEM1	-7103	14479
WFS1	-7096	14466
CANX	-7092	14462
PDIA3	-7086	14454
SLC17A5	-7072	14434
TMED2	-7071	14433
KLHL21	-7069	14429
MCFD2	-7065	14425
ARRB1	-7062	14420
GCNT3	-7052	14407
GFPT1	-7051	14406

Click HERE to show all gene set members

All member genes

	x	abs
AAAS	2965	5701
ACTB	-5057	10683
ACTL6A	-1378	2772
ACTR10	5570	10590
ACTR1A	-5162	10903
ACTR5	4150	7892
ACTR8	-3157	6616
ADAM10	-2671	5549
ADAMTS1	3770	7179
ADAMTS10	6971	13383
ADAMTS13	5043	9541
ADAMTS17	-2445	5058
ADAMTS2	6939	13309
ADAMTS4	1241	2448
ADAMTS6	6501	12405
ADAMTS7	2880	5554
ADAMTS9	6402	12207
ADAMTSL2	-3475	7330
ADAMTSL3	2956	5688
ADAMTSL4	7040	13538
ADAMTSL5	-1090	2224
ADRM1	-3551	7511
AFP	-4151	8777
AGBL2	5191	9809
AGBL3	1865	3660
AGBL5	2606	5032
AGTPBP1	5818	11045
AHSG	25	62
ALB	3096	5965
ALG1	-4352	9207
ALG10	2654	5133
ALG10B	5899	11213
ALG11	-5957	12520
ALG12	-6081	12752
ALG13	1348	2687
ALG14	-3206	6723
ALG2	-6554	13631
ALG3	-6601	13700
ALG5	-6471	13488
ALG6	4943	9374
ALG8	1117	2188
ALG9	-426	865
AMDHD2	5414	10267
AMFR	-2698	5612
ANK1	-4656	9901
ANK2	-6778	13993
ANK3	303	591
ANKRD28	4146	7882
ANKRD9	2692	5202
ANO8	-168	350
APC	-1818	3716
APLP2	-3330	7009
APOA1	6993	13433
APOA2	-6307	13191
APOA5	4116	7816
APOB	-2964	6172
APOE	-3670	7759
APOL1	4896	9284
APP	-6492	13532
ARCN1	-6505	13549
AREG	-4847	10258
ARF1	-6021	12642
ARF3	-2430	5040
ARF4	-5812	12225
ARF5	4743	8998
ARFGAP1	-1587	3224
ARFGAP2	1283	2547
ARFGAP3	-4817	10209
ARRB1	-7062	14420
ARRB2	-3248	6824
ARSA	2878	5552
ARSB	-6939	14246
ARSD	-4527	9613
ARSG	7341	14366
ARSI	6118	11653
ARSK	-1251	2519
ART4	6681	12770
ASB1	-4171	8818
ASB13	6386	12175
ASB18	-601	1231
ASB2	-6960	14280
ASB3	3026	5827
ASB4	-3822	8067
ASB6	-5243	11077
ASB7	-3889	8217
ASB8	-1103	2243
ASB9	5150	9735
ASGR1	-1889	3870
ASGR2	-2985	6225
ASXL1	-1908	3914
ASXL2	-5845	12292
ATXN3	3714	7075
ATXN7	-4932	10416
AURKA	1224	2412
AURKB	6883	13190
AXIN1	-4215	8908
AXIN2	-5745	12097
B3GALNT2	-2427	5034
B3GLCT	-5422	11411
B3GNT2	-2359	4879
B3GNT3	4629	8781
B3GNT4	-1829	3741
B3GNT7	1584	3122
B3GNT8	3574	6820
B3GNT9	-4301	9094
B3GNTL1	1392	2766
B4GALNT2	1387	2758
B4GALT1	-262	540
B4GALT2	-2487	5152
B4GALT3	-4852	10265
B4GALT4	2602	5027
B4GALT5	6846	13121
B4GALT6	2881	5555
B4GAT1	-3691	7803
BABAM1	2979	5721
BAP1	-2760	5752
BARD1	6138	11687
BCL10	-4471	9472
BECN1	-2900	6036
BET1	457	896
BET1L	3487	6669
BGLAP	241	475
BIRC2	-499	1007
BIRC3	3477	6654
BIRC5	5174	9771
BLM	5994	11423
BMI1	-4180	8838
BMP4	-6869	14148
BPIFB2	-4967	10473
BRCA1	5107	9663
BRCC3	2358	4560
BST1	713	1408
BTBD1	37	81
BTRC	1386	2757
C1GALT1	742	1485
C1GALT1C1	-2939	6112
C3	7357	14417
C4A	7346	14381
CALM1	-655	1340
CALR	-7142	14529
CALU	-4521	9602
CAMKMT	962	1898
CAND1	-1658	3381
CANX	-7092	14462
CAPZA1	-4855	10272
CAPZA2	-1549	3143
CAPZB	-1169	2376
CASP8AP2	5260	9946
CBX2	6958	13350
CBX4	-4063	8580
CBX5	7222	14012
CBX8	-4370	9242
CCDC22	-1703	3481
CCDC8	2470	4762
CCNA2	6594	12587
CCNF	1291	2569
CCP110	6203	11807
CD109	-5016	10579
CD55	-6517	13575
CD59	-3245	6818
CDC20	5650	10732
CDC25A	5954	11334
CDC34	-5516	11619
CDC73	-4683	9943
CDCA8	6649	12700
CDH2	-2339	4845
CDK1	7230	14027
CDKN2A	3704	7056
CEACAM5	1008	1981
CETN2	5801	11018
CHD3	-1321	2661
CHGB	2226	4319
CHM	5425	10293
CHML	1746	3428
CHST10	6919	13262
CISH	6003	11440
CKAP4	-3939	8327
CLSPN	7014	13484
CMAS	5724	10871
CNIH1	212	416
CNIH3	-1958	4025
COG1	4586	8708
COG2	-4254	8997
COG3	-5948	12497
COG4	1972	3852
COG5	-3964	8389
COG6	3264	6266
COG7	4792	9093
COG8	6745	12910
COL7A1	5362	10152
COMMD1	4304	8164
COMMD10	117	233
COMMD2	395	774
COMMD3	4983	9446
COMMD4	-2	7
COMMD5	-4916	10389
COMMD6	5668	10773
COMMD7	5185	9798
COMMD8	710	1404
COMMD9	-3531	7455
COPA	-3958	8376
COPB1	-4098	8664
COPB2	-6532	13594
COPE	-5961	12527
COPG1	-5135	10840
COPG2	6142	11691
COPS2	-5161	10902
COPS3	-4618	9810
COPS4	-28	51
COPS5	-3031	6317
COPS6	-3063	6380
COPS7A	5653	10738
COPS7B	-839	1713
COPS8	-4894	10337
COPZ1	782	1554
CP	7325	14292
CPM	1144	2250
CREBBP	-3888	8214
CSF1	-6711	13888
CSNK1D	-5722	12038
CST3	3732	7101
CTBP1	-41	73
CTR9	-3895	8230
CTSA	-6288	13149
CTSC	-4446	9398
CUL1	-4129	8725
CUL2	359	703
CUL3	-3056	6363
CUL4A	-2265	4702
CUL4B	-4685	9945
CUL5	-1229	2485
CUL7	4377	8310
CUL9	6773	12968
CYLD	-6066	12727
CYR61	-2582	5367
DAD1	-6240	13053
DAG1	-2174	4498
DAXX	3635	6929
DCAF10	-5421	11410
DCAF11	-6142	12860
DCAF13	4652	8826
DCAF16	5344	10105
DCAF17	3819	7273
DCAF4	5420	10278
DCAF5	-4547	9642
DCAF6	-2469	5119
DCAF7	5557	10568
DCAF8	4645	8816
DCTN1	-1635	3338
DCTN2	-3957	8375
DCTN3	1457	2887
DCTN4	-1937	3979
DCTN5	-3634	7690
DCTN6	-318	666
DCUN1D1	1428	2843
DCUN1D2	-4601	9784
DCUN1D3	-5821	12244
DCUN1D4	-400	815
DCUN1D5	-1895	3884
DDA1	-5633	11862
DDB1	-5688	11967
DDB2	6754	12925
DDOST	-6429	13410
DDX17	-3321	6985
DDX5	-6665	13814
DDX58	-927	1883
DERL1	-6423	13398
DERL2	-7046	14399
DHDDS	2399	4636
DHPS	3475	6649
DNAJC24	2574	4977
DNAJC3	-7131	14516
DNMT1	2134	4159
DNMT3A	3360	6452
DNMT3B	6957	13348
DOHH	-4258	9002
DOLK	108	213
DOLPP1	-4988	10517
DPAGT1	-6046	12688
DPH1	-5397	11373
DPH2	-5629	11858
DPH3	-5074	10720
DPH5	6731	12882
DPH6	5513	10486
DPH7	-2301	4778
DPM1	-1233	2494
DPM2	-2111	4373
DPM3	3217	6189
DTL	4577	8690
DYNC1H1	-3614	7639
DYNC1I2	-2780	5783
DYNC1LI1	-2519	5237
DYNC1LI2	-3897	8235
DYNLL1	2509	4853
DYNLL2	6044	11507
EDEM1	-7103	14479
EDEM2	-5520	11628
EDEM3	-1903	3904
EEF1A1	-4138	8740
EEF2	-5049	10659
EEF2KMT	867	1703
EID3	-2695	5599
EIF5A	-5678	11952
EIF5A2	-4929	10412
ELOB	-3004	6272
ELOC	645	1265
ENGASE	6457	12309
EP300	-6470	13485
EPAS1	-4915	10387
ERCC8	-2409	4995
ETFB	2051	4002
ETFBKMT	3805	7248
EVA1A	-4709	9995
F10	5732	10888
F2	635	1246
F5	831	1638
F7	6332	12069
F8	735	1460
FAM20A	7332	14315
FAM20C	4945	9378
FBN1	7148	13813
FBXL12	-1137	2320
FBXL13	-870	1783
FBXL14	-2614	5439
FBXL15	612	1200
FBXL16	7269	14129
FBXL18	-1507	3067
FBXL19	-2110	4369
FBXL20	-3941	8336
FBXL22	3108	5990
FBXL3	-2027	4168
FBXL4	4801	9111
FBXL5	5669	10775
FBXL8	2924	5631
FBXO10	18	43
FBXO11	-3853	8152
FBXO15	3559	6797
FBXO17	5986	11405
FBXO2	-78	158
FBXO21	4978	9436
FBXO22	4762	9038
FBXO27	3623	6911
FBXO30	137	270
FBXO31	-5485	11563
FBXO32	-5299	11189
FBXO4	4180	7948
FBXO41	6136	11685
FBXO44	-4694	9964
FBXO6	3932	7468
FBXO7	947	1865
FBXO9	-1843	3776
FBXW10	-2540	5268
FBXW11	-3784	7986
FBXW2	-294	602
FBXW4	6039	11502
FBXW5	-5945	12489
FBXW7	-2564	5325
FBXW8	3716	7078
FBXW9	890	1747
FEM1A	-1576	3196
FEM1B	-103	209
FEM1C	-4764	10115
FGA	7336	14346
FGF23	2097	4091
FGG	6697	12809
FKBP8	6242	11886
FN1	-3115	6525
FN3K	1324	2638
FN3KRP	6434	12265
FOXK1	-4324	9151
FOXK2	-6570	13656
FOXO4	-2077	4276
FPGT	5627	10685
FSTL3	-5252	11092
FUCA1	2696	5210
FUCA2	-6538	13600
FUOM	2573	4976
FURIN	-6683	13851
FUT3	-7001	14335
FUT8	-5134	10839
GALNT1	-816	1659
GALNT10	-4763	10114
GALNT11	7125	13771
GALNT13	-810	1646
GALNT16	2794	5384
GALNT2	6578	12555
GALNT3	-3227	6774
GALNT4	2438	4706
GALNT6	4939	9366
GALNT7	-4049	8555
GAN	-3641	7702
GANAB	2813	5417
GAS6	2708	5226
GBF1	-4981	10507
GCNT1	679	1328
GCNT3	-7052	14407
GCNT4	3690	7025
GFPT1	-7051	14406
GGCX	-4023	8504
GLB1	1557	3064
GMDS	-3350	7053
GMPPA	-6346	13267
GMPPB	-6844	14096
GNE	6051	11517
GNPNAT1	2394	4628
GOLGA2	-5310	11209
GOLGB1	-3498	7386
GOLM1	-4779	10136
GORASP1	1903	3727
GOSR1	621	1215
GOSR2	1238	2441
GP2	806	1595
GPAA1	-2406	4990
GPC3	4191	7971
GPLD1	-4556	9667
GPS1	-3506	7406
HCFC1	-6060	12714
HDAC1	-2676	5563
HDAC2	-338	693
HDAC4	-1478	2998
HDAC7	130	254
HERC2	-3739	7888
HGS	-4210	8898
HIC1	-2592	5389
HIF1A	-4165	8807
HIF3A	4444	8437
HIPK2	6284	11978
HLA-A	5777	10971
HLA-B	2764	5329
HLTF	6769	12961
HNRNPC	1814	3563
HNRNPK	-2808	5839
HRC	5955	11335
HSP90B1	-7129	14514
HSPA8	-4654	9895
ICMT	2988	5741
IDE	-4045	8543
IFIH1	6646	12693
IGFBP1	-3931	8301
IGFBP3	6060	11532
IGFBP4	5060	9571
IGFBP7	4272	8108
IKBKE	-787	1593
IKBKG	-5946	12493
INCENP	5290	10005
ING2	-711	1437
INO80	-3397	7157
INO80B	2818	5426
INO80C	-185	380
INO80D	-3312	6967
INO80E	3921	7449
ITIH2	1740	3417
JOSD1	-5993	12588
JOSD2	3811	7257
KAT2A	5077	9597
KAT2B	-4792	10158
KBTBD6	6796	13016
KBTBD7	6772	12967
KBTBD8	2943	5662
KCTD6	-178	368
KCTD7	-3550	7510
KDELR1	-5094	10752
KDELR2	-5893	12387
KDELR3	976	1922
KDM1B	-4647	9876
KEAP1	-6482	13510
KIN	3578	6833
KLHL11	-1223	2475
KLHL13	4291	8137
KLHL2	-3269	6866
KLHL20	3344	6424
KLHL21	-7069	14429
KLHL22	5084	9610
KLHL25	-215	441
KLHL42	-4874	10303
KLHL5	-991	2025
KLHL9	3712	7071
KNG1	7382	14503
KTN1	-3223	6769
L3MBTL2	789	1567
LAMB1	3783	7198
LAMB2	495	978
LAMC1	-1300	2611
LARGE1	-5056	10682
LARGE2	-2856	5939
LEO1	-3088	6444
LGALS1	-6649	13778
LMAN1	-3431	7220
LMAN2	-6558	13641
LMAN2L	-3429	7218
LMO7	-1246	2512
LRR1	-494	1000
LRRC41	1992	3889
LRRC49	-625	1273
LTBP1	-1904	3905
LY6E	4473	8481
LYPD3	-297	613
MAGT1	-7045	14398
MAN1A1	-1021	2084
MAN1A2	-6460	13466
MAN1B1	-3561	7534
MAN1C1	3072	5920
MAN2A1	-1040	2117
MAN2A2	-2336	4840
MANEA	4202	7987
MAP3K7	3767	7172
MAT2B	1703	3339
MATN3	7298	14207
MAVS	1695	3323
MBD1	-4444	9395
MBD5	-3114	6524
MBD6	-6742	13936
MBTPS1	-5958	12523
MCFD2	-7065	14425
MCRS1	-1472	2985
MDC1	-3323	6989
MDM2	-956	1942
MDM4	-2561	5318
MELTF	7295	14199
MEN1	1298	2581
METTL21A	5233	9883
METTL22	2346	4532
MFGE8	5552	10560
MGAT1	-6401	13371
MGAT2	-3327	7002
MGAT4A	-5018	10584
MGAT4B	-6279	13132
MGAT4C	1714	3364
MGAT5	-5854	12324
MIA3	-7049	14404
MITF	267	519
MLEC	-6902	14193
MOGS	-2275	4728
MPDU1	3718	7080
MPI	5076	9596
MSLN	4555	8649
MTA1	1810	3553
MUC13	-1524	3097
MUC15	4828	9153
MUC20	-1019	2082
MUC5B	7378	14487
MUL1	-5892	12386
MVD	7302	14220
MXRA8	-4064	8582
MYC	1892	3708
MYSM1	1066	2098
NAE1	5740	10901
NAGK	4508	8559
NANP	483	957
NANS	-6906	14204
NAPA	-5921	12433
NAPB	-419	853
NAPG	-3872	8187
NCOA1	-4665	9914
NCOA2	4780	9072
NCOR2	-4409	9331
NDC1	-1490	3023
NEDD8	580	1131
NEGR1	1869	3667
NEU1	-6752	13953
NEU3	7085	13653
NEU4	6950	13335
NEURL2	2359	4562
NFKB2	-1311	2634
NFKBIA	-6437	13427
NFRKB	-4026	8510
NGLY1	-2909	6049
NICN1	4839	9177
NOD1	5449	10348
NOP58	5612	10662
NOTUM	6788	12998
NPM1	-2033	4183
NR1H2	193	373
NR1H3	4678	8878
NR1H4	-6037	12674
NR1I2	5656	10746
NR2C1	535	1052
NR3C1	-4005	8476
NR3C2	1520	2999
NR5A1	-4679	9936
NR5A2	-5547	11680
NRIP1	570	1114
NRN1L	4081	7736
NSF	-4839	10249
NSMCE1	6680	12769
NSMCE2	-4496	9534
NSMCE3	1095	2144
NSMCE4A	-1462	2966
NUB1	3894	7395
NUCB1	-5103	10770
NUDT14	-4170	8814
NUP107	6076	11561
NUP133	1362	2708
NUP153	2712	5230
NUP155	4796	9102
NUP160	-329	683
NUP188	-4991	10521
NUP205	-5275	11144
NUP210	6802	13025
NUP214	-1926	3957
NUP35	5982	11387
NUP37	7100	13706
NUP43	2808	5410
NUP50	-4733	10047
NUP54	3310	6371
NUP58	2380	4603
NUP62	-299	618
NUP85	4178	7946
NUP88	-4777	10134
NUP93	5831	11067
NUP98	-3764	7940
NUS1	-6395	13362
OBSL1	2391	4622
OGT	6452	12301
OS9	-6986	14320
OTOA	87	171
OTUB1	-293	600
OTUB2	5916	11254
OTUD3	-2342	4849
OTUD5	-5944	12487
OTUD7A	589	1152
OTUD7B	-1911	3920
OTULIN	-2499	5175
P4HB	-6884	14170
PAF1	1828	3589
PARK7	-2508	5199
PARP1	2974	5715
PCGF2	-5881	12369
PCNA	6523	12452
PCSK9	7381	14502
PDIA3	-7086	14454
PDIA6	-7106	14482
PEX10	2668	5162
PEX12	4742	8996
PEX13	-721	1454
PEX14	-3636	7694
PEX2	4569	8675
PEX5	-346	707
PGAP1	5952	11332
PGM3	-5395	11367
PHC1	-4280	9053
PHC2	3713	7072
PHC3	843	1660
PIAS1	-272	560
PIAS2	388	761
PIAS3	-1381	2775
PIAS4	-5022	10596
PIGA	-4278	9048
PIGB	4297	8147
PIGC	2130	4155
PIGF	4815	9133
PIGG	-6186	12950
PIGH	-1877	3848
PIGK	6215	11827
PIGL	5841	11096
PIGM	5248	9913
PIGN	-1322	2662
PIGO	2315	4481
PIGP	3397	6509
PIGQ	4551	8638
PIGS	-609	1243
PIGT	-1154	2351
PIGU	1074	2112
PIGV	4200	7983
PIGW	-5277	11146
PIGX	63	124
PIGY	948	1867
PIGZ	5536	10536
PLAUR	4485	8513
PML	1051	2057
PMM1	-2658	5521
PMM2	-5187	10956
PNPLA2	-5366	11306
POFUT2	-264	542
POLB	-4316	9130
POM121	-6353	13281
POM121C	-6045	12687
POMGNT1	3215	6187
POMGNT2	4488	8517
POMK	2475	4768
POMT1	-3914	8266
POMT2	-6788	14007
PPARA	-6722	13906
PPARG	-3168	6636
PPARGC1A	-5869	12350
PPP6C	-5241	11074
PPP6R1	-6511	13558
PPP6R3	-623	1271
PREB	1446	2868
PRKCSH	-5934	12463
PRKDC	-2300	4777
PRMT3	5707	10843
PROC	6720	12863
PROS1	6053	11519
PROZ	6212	11823
PRSS23	655	1288
PSMA1	-5730	12052
PSMA2	-5801	12203
PSMA3	-3078	6422
PSMA4	-4211	8902
PSMA5	-2715	5657
PSMA6	-126	261
PSMA7	-892	1820
PSMB1	1054	2062
PSMB10	423	838
PSMB2	1876	3678
PSMB3	-1915	3928
PSMB4	-1144	2330
PSMB5	-742	1484
PSMB6	-4888	10326
PSMB7	-4372	9253
PSMB9	5491	10430
PSMC1	-5564	11724
PSMC2	-2389	4948
PSMC3	-1509	3070
PSMC4	-4808	10196
PSMC5	-4091	8646
PSMC6	-4878	10307
PSMD1	-5351	11280
PSMD10	4933	9356
PSMD11	-432	879
PSMD12	4303	8163
PSMD13	-2577	5353
PSMD14	5974	11371
PSMD2	-6435	13423
PSMD3	-5535	11655
PSMD4	4567	8670
PSMD5	5116	9676
PSMD6	-5951	12502
PSMD7	4942	9371
PSMD8	-2928	6091
PSMD9	-4638	9853
PSME1	-2348	4861
PSME2	-5481	11555
PSME3	-3813	8052
PSME4	-6450	13450
PSMF1	-6663	13810
PTEN	-4721	10023
PTP4A2	-5085	10739
PTRH2	-5409	11393
PUM2	-5288	11167
QSOX1	-1250	2518
RAB10	1625	3205
RAB11A	4527	8597
RAB11B	-876	1793
RAB12	950	1872
RAB13	3724	7089
RAB14	3647	6952
RAB15	-3665	7753
RAB17	-7135	14521
RAB18	-372	760
RAB1A	-3307	6957
RAB1B	-3479	7340
RAB20	-6619	13727
RAB21	2694	5208
RAB22A	-6525	13585
RAB23	4722	8961
RAB24	4024	7638
RAB26	2740	5288
RAB27A	3011	5804
RAB29	1630	3213
RAB2A	-5379	11326
RAB2B	-1387	2784
RAB30	288	562
RAB31	-4876	10305
RAB32	-5287	11166
RAB33B	-2981	6213
RAB35	-5270	11131
RAB36	4950	9394
RAB37	6989	13426
RAB39B	-1774	3618
RAB3A	4309	8176
RAB3B	-1738	3544
RAB3D	1600	3155
RAB40B	4658	8839
RAB40C	-5019	10588
RAB42	4442	8434
RAB43	-6699	13874
RAB4A	-2148	4453
RAB4B	3174	6116
RAB5A	-5408	11392
RAB5B	2913	5611
RAB5C	-3129	6565
RAB6A	1296	2578
RAB6B	1396	2780
RAB7A	-5810	12220
RAB8A	-2247	4658
RAB8B	4676	8875
RAB9A	-6014	12633
RABGGTA	-4673	9926
RABGGTB	-5199	10986
RAD18	6045	11508
RAD21	601	1178
RAD23A	7141	13802
RAD23B	3141	6054
RAD52	6185	11769
RAE1	4394	8335
RANBP2	-4	9
RANGAP1	3458	6615
RARA	-6269	13109
RBBP5	-101	204
RBBP7	5134	9712
RBX1	-3714	7850
RCE1	-1124	2289
RCN1	3434	6562
RECK	7128	13774
RELA	-2632	5468
RENBP	-5761	12130
RFT1	5083	9608
RFWD2	-2022	4150
RHOA	-5294	11182
RHOT1	4106	7793
RING1	4067	7710
RIPK1	-2886	6000
RIPK2	-5779	12158
RNF103	-6135	12848
RNF123	-4681	9939
RNF128	-1375	2768
RNF135	126	247
RNF139	-3064	6382
RNF144A	4501	8547
RNF146	825	1622
RNF168	-3576	7562
RNF181	-4815	10206
RNF185	-6359	13291
RNF2	2454	4732
RNF20	5837	11085
RNF40	-5459	11493
RNF5	-6629	13745
RNF7	-611	1249
RORA	-5875	12360
RPA1	-5008	10563
RPN1	-7013	14350
RPN2	-6193	12964
RPS2	-3462	7293
RPS27A	-2773	5776
RRAGA	2609	5038
RTF1	-1751	3574
RTN4RL2	5004	9479
RUVBL1	5317	10058
RWDD3	6644	12691
RXRA	-4073	8607
SAE1	1799	3527
SAFB	-6184	12947
SAR1B	-2973	6198
SATB2	-2932	6101
SCFD1	485	960
SCMH1	6656	12722
SDC2	147	289
SEC13	-6812	14049
SEC16A	-5971	12546
SEC16B	6744	12908
SEC22A	3312	6374
SEC22B	859	1690
SEC22C	-1684	3433
SEC23A	-2717	5659
SEC23IP	390	767
SEC24A	-6839	14088
SEC24B	-5475	11541
SEC24C	-6236	13047
SEC24D	-7134	14520
SEC31A	-5766	12138
SEH1L	-4472	9474
SEL1L	-7124	14508
SELENOS	-7117	14498
SEM1	-3130	6566
SENP1	-886	1811
SENP2	-3731	7874
SENP5	-5170	10920
SENP8	6135	11684
SERPINA1	4014	7622
SERPINA10	4206	7992
SERPINC1	-6588	13683
SERPIND1	6689	12796
SHISA5	4853	9203
SHPRH	6150	11706
SIAH2	-6666	13819
SIN3A	-5884	12373
SKP1	-544	1117
SKP2	5946	11323
SLC17A5	-7072	14434
SLC35A1	3906	7418
SLC35C1	-6667	13821
SMAD1	4977	9435
SMAD2	-4087	8639
SMAD3	-6145	12871
SMAD4	2742	5290
SMAD7	3117	6006
SMC1A	784	1560
SMC3	2546	4924
SMC5	-2095	4328
SMC6	2150	4184
SMURF2	-5253	11093
SNX3	-4858	10279
SOCS2	-1346	2710
SOCS3	7374	14476
SOCS5	-6643	13766
SOCS6	-5467	11523
SP100	-2455	5083
SP3	-4660	9908
SPON2	-6404	13375
SPP1	-5872	12355
SPP2	1592	3138
SPSB1	1077	2118
SPSB2	-1306	2622
SPSB3	-4739	10054
SPTAN1	2385	4610
SPTBN1	-4901	10356
SPTBN2	3883	7379
SRD5A3	4758	9027
ST3GAL1	-5905	12408
ST3GAL2	-4518	9594
ST3GAL3	5918	11257
ST3GAL4	-6801	14033
ST3GAL5	5090	9630
ST3GAL6	-3252	6829
ST6GAL1	-1828	3739
ST6GALNAC4	-6726	13912
ST6GALNAC6	-4820	10212
ST8SIA1	2289	4428
ST8SIA5	-1758	3583
STAG1	-3341	7037
STAG2	-2617	5443
STAM	5109	9665
STAM2	3080	5933
STAMBP	5873	11154
STAMBPL1	2213	4302
STC2	-6224	13029
STS	-4430	9373
STT3A	-6796	14026
STX17	2586	4997
STX5	-5300	11191
SUDS3	-2287	4748
SUMF1	6175	11754
SUMF2	1101	2158
SUMO1	3308	6365
SUMO2	1568	3089
SUMO3	4906	9299
SUZ12	346	664
SVBP	-1922	3948
SYVN1	-7108	14485
TAB1	6687	12789
TADA2B	-5182	10948
TADA3	-1216	2462
TAF10	626	1223
TAF9B	6106	11625
TBC1D20	-6203	12985
TDG	-3113	6520
TECTA	2402	4639
TECTB	-6219	13015
TF	5850	11111
TFG	-5336	11250
TFPT	1213	2390
TGFA	-4511	9574
TGFB1	-6934	14241
TGFBR1	-2620	5447
TGFBR2	-3644	7714
TGOLN2	-2105	4352
THBS1	5988	11408
THBS2	2512	4856
THRA	-2996	6251
THRB	-3951	8360
THSD1	-5333	11244
THSD4	-6356	13286
TIMP1	-6294	13158
TMED10	-6116	12817
TMED2	-7071	14433
TMED3	-4057	8567
TMED7	-6933	14240
TMED9	-6502	13545
TMEM115	-6764	13976
TMEM129	4918	9321
TMEM132A	2376	4597
TNFAIP3	4359	8284
TNIP1	-4433	9381
TNIP2	-1314	2640
TNKS	-4790	10153
TNKS2	-3213	6742
TOMM20	676	1324
TOMM70	-2797	5819
TOP1	-6472	13490
TOP2A	6875	13176
TOP2B	-3712	7845
TOPORS	-2753	5743
TP53	-2020	4144
TP53BP1	4788	9089
TPGS1	-5251	11091
TPGS2	5616	10668
TPR	565	1105
TPST1	-2126	4399
TPST2	-2873	5975
TRAF2	-577	1180
TRAF3	-356	729
TRAF6	1597	3150
TRAPPC1	3089	5956
TRAPPC10	-6585	13677
TRAPPC2	3547	6775
TRAPPC2L	-4576	9709
TRAPPC3	-4032	8524
TRAPPC4	1781	3487
TRAPPC5	239	470
TRAPPC6A	7244	14069
TRAPPC6B	2584	4993
TRAPPC9	5033	9528
TRIM13	1883	3695
TRIM25	-5492	11574
TRIM27	-4835	10241
TRIM28	-3099	6471
TRIM4	-4229	8937
TRRAP	-3581	7571
TTL	-2640	5487
TTLL1	6723	12868
TTLL11	-6233	13041
TTLL12	-556	1140
TTLL3	7102	13715
TTLL4	2011	3926
TTLL5	-713	1443
TTLL7	-3685	7789
TTLL9	-1023	2086
TUBA1A	4706	8932
TUBA1B	7094	13681
TUBA1C	6761	12940
TUBB1	2717	5236
TUBB2A	1290	2568
TUBB2B	4184	7952
TUBB3	436	858
TUBB4B	6758	12934
TUBB6	-1115	2268
TUBB8	4034	7651
TULP4	-4002	8471
TUSC3	-1219	2465
UAP1	-898	1828
UBA1	516	1021
UBA2	-3913	8263
UBA3	-1275	2562
UBA52	-5068	10707
UBA6	-2266	4704
UBB	-4263	9013
UBC	779	1551
UBD	3463	6630
UBE2A	3752	7140
UBE2B	-2586	5375
UBE2C	7137	13793
UBE2D1	3523	6734
UBE2D2	-913	1857
UBE2D3	-3997	8449
UBE2E1	3733	7102
UBE2E3	-2654	5512
UBE2F	-5885	12374
UBE2G1	-5763	12134
UBE2G2	-718	1451
UBE2H	5369	10168
UBE2I	-1318	2653
UBE2J2	-6232	13040
UBE2K	383	750
UBE2L3	-3143	6589
UBE2M	-4337	9174
UBE2N	1836	3604
UBE2Q2	2642	5107
UBE2R2	-386	790
UBE2S	-1872	3839
UBE2T	5710	10846
UBE2V2	3369	6467
UBE2W	-1973	4047
UBE2Z	-964	1959
UBXN1	-5450	11466
UBXN7	1120	2192
UCHL3	-5231	11055
UCHL5	443	875
UGGT1	-6954	14270
UGGT2	1425	2839
UHRF2	-2752	5740
UIMC1	-6627	13741
USO1	-3509	7413
USP10	1016	1999
USP11	2763	5328
USP12	-3488	7363
USP13	6054	11521
USP14	5232	9882
USP15	-4344	9193
USP16	-6545	13615
USP18	5875	11159
USP19	-2419	5014
USP2	-5430	11427
USP20	1248	2470
USP21	2804	5405
USP22	-5265	11124
USP24	-2786	5792
USP25	-325	676
USP28	-1668	3404
USP3	-3962	8383
USP30	6349	12091
USP33	1924	3761
USP34	-4441	9391
USP37	3800	7241
USP4	1449	2874
USP42	-5109	10780
USP47	-1849	3795
USP48	2408	4648
USP49	1405	2797
USP5	-2837	5894
USP7	134	258
USP8	-2820	5864
USP9X	-4318	9136
VASH1	2462	4751
VASH2	5945	11320
VCAN	-5649	11899
VCP	-6720	13902
VCPIP1	-5042	10640
VCPKMT	4329	8222
VDAC1	-1027	2092
VDAC2	-2869	5966
VDAC3	-273	561
VGF	-6864	14140
VHL	-6491	13531
VNN1	5548	10554
VNN3	6337	12074
VWA1	2832	5457
WAC	-5965	12537
WDR20	-3937	8319
WDR48	543	1063
WDR5	2561	4953
WDR61	452	889
WDTC1	-1303	2617
WFS1	-7096	14466
WRN	3032	5841
WSB1	-4879	10308
WSB2	-7029	14373
XPC	5353	10123
XPNPEP2	6043	11506
XRCC4	3376	6479
YKT6	-4899	10349
YOD1	-6141	12859
YY1	-5214	11015
ZBED1	3448	6594
ZNF131	-3603	7607
ZNF350	2186	4246
ZRANB1	-5895	12391

---

---

Peptide chain elongation

Peptide chain elongation

metric	value
setSize	86
pMANOVA	2.62e-11
p.adjustMANOVA	1.03e-09
s.dist	0.43
s.x	-0.405
s.abs	-0.143
p.x	8.24e-11
p.abs	0.0219

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
EEF1A1	-4138	8740
EEF2	-5049	10659
FAU	-4990	10520
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
UBA52	-5068	10707

---

---

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

metric	value
setSize	91
pMANOVA	2.7e-11
p.adjustMANOVA	1.03e-09
s.dist	0.419
s.x	-0.406
s.abs	-0.105
p.x	2.32e-11
p.abs	0.0842

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
EIF4G1	-5901	12400
ETF1	-6952	14268
FAU	-4990	10520
GSPT1	-6825	14070
NCBP1	-2151	4458
NCBP2	6823	13081
PABPC1	-3543	7490
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
UBA52	-5068	10707
UPF1	-4700	9973

---

---

Regulation of Complement cascade

Regulation of Complement cascade

metric	value
setSize	30
pMANOVA	3.18e-11
p.adjustMANOVA	1.18e-09
s.dist	0.719
s.x	0.555
s.abs	0.457
p.x	1.43e-07
p.abs	1.5e-05

Top 20 genes

Gene	x	abs
SERPING1	7387	14532
C1S	7360	14430
C3	7357	14417
CFB	7350	14394
C4A	7346	14381
C8B	7343	14372
C4B	7286	14173
C8A	7235	14042
C5	7218	14003
C1R	7201	13954
VTN	6910	13246
CFI	6891	13206
C5AR1	6719	12862
C6	6620	12636
PROS1	6053	11519
CLU	5647	10723
C4BPA	5221	9865
CD46	5036	9531
C7	4745	9004
CPB2	4337	8234

Click HERE to show all gene set members

All member genes

	x	abs
C1R	7201	13954
C1S	7360	14430
C2	4264	8098
C3	7357	14417
C4A	7346	14381
C4B	7286	14173
C4BPA	5221	9865
C4BPB	-6787	14006
C5	7218	14003
C5AR1	6719	12862
C5AR2	3489	6671
C6	6620	12636
C7	4745	9004
C8A	7235	14042
C8B	7343	14372
C8G	-2213	4585
CD19	-472	954
CD46	5036	9531
CD55	-6517	13575
CD59	-3245	6818
CFB	7350	14394
CFI	6891	13206
CLU	5647	10723
CPB2	4337	8234
CPN1	4039	7658
CPN2	-110	221
F2	635	1246
PROS1	6053	11519
SERPING1	7387	14532
VTN	6910	13246

---

---

rRNA processing in the nucleus and cytosol

rRNA processing in the nucleus and cytosol

metric	value
setSize	184
pMANOVA	4.11e-11
p.adjustMANOVA	1.49e-09
s.dist	0.292
s.x	-0.278
s.abs	-0.0894
p.x	7.82e-11
p.abs	0.0368

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
BMS1	-4769	10122
BOP1	-4381	9269
BYSL	-2637	5477
C1D	3482	6660
CSNK1D	-5722	12038
CSNK1E	3247	6238
DCAF13	4652	8826
DDX21	-256	530
DDX47	-4068	8593
DDX49	-6809	14045
DDX52	-3894	8227
DHX37	-5250	11090
DIMT1	2382	4606
DIS3	-1573	3190
DKC1	-1249	2517
EBNA1BP2	-3613	7630
EMG1	7347	14384
ERI1	-2490	5155
EXOSC1	3486	6667
EXOSC10	-341	697
EXOSC2	3779	7192
EXOSC3	-3453	7270
EXOSC4	3220	6193
EXOSC5	-4766	10117
EXOSC6	-6503	13547
EXOSC7	5196	9819
EXOSC8	472	928
EXOSC9	3293	6333
FAU	-4990	10520
FBL	-1548	3141
FCF1	-2713	5649
FTSJ3	2052	4006
GAR1	-3015	6286
GNL3	-5332	11243
HEATR1	-1324	2664
IMP3	-4633	9837
IMP4	-4940	10435
ISG20L2	-3623	7668
KRR1	924	1808
LAS1L	7022	13502
LTV1	-5474	11539
MPHOSPH10	-6827	14072
MPHOSPH6	5619	10672
NAT10	3342	6419
NCL	-1840	3770
NHP2	-4261	9010
NIP7	-2165	4480
NOB1	-3772	7960
NOC4L	-1552	3148
NOL11	4020	7634
NOL12	-3773	7961
NOL6	1999	3901
NOL9	-4954	10455
NOP10	-4958	10460
NOP14	-5209	11001
NOP2	-3859	8162
NOP56	-1145	2332
NOP58	5612	10662
PDCD11	3334	6405
PELP1	-2894	6020
PES1	-3505	7405
PNO1	-5758	12126
PWP2	-2005	4115
RBM28	771	1540
RCL1	-942	1910
RIOK1	2711	5229
RIOK2	-4018	8498
RIOK3	-6332	13237
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPP14	1309	2606
RPP30	1439	2860
RPP38	1564	3081
RPP40	1770	3469
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
RRP1	-5133	10838
RRP36	-6354	13283
RRP7A	2006	3915
RRP9	-2591	5388
SENP3	-1399	2810
SNU13	-129	265
TBL3	-794	1617
TEX10	-4283	9059
THUMPD1	-270	553
TRMT112	-3869	8181
TSR1	-851	1732
TSR3	-466	947
UBA52	-5068	10707
UTP11	-1337	2685
UTP14A	-5799	12194
UTP14C	-6243	13057
UTP15	-2509	5201
UTP18	-4476	9483
UTP20	-2811	5845
UTP3	4280	8119
UTP4	-6111	12808
UTP6	-1836	3755
WDR12	3814	7261
WDR18	2127	4149
WDR3	5692	10815
WDR36	5735	10892
WDR43	-4193	8863
WDR46	4709	8939
WDR75	3573	6819
XRN2	-3427	7216

---

---

Metabolism of RNA

Metabolism of RNA

metric	value
setSize	658
pMANOVA	5.13e-11
p.adjustMANOVA	1.81e-09
s.dist	0.158
s.x	-0.156
s.abs	-0.0205
p.x	1.16e-11
p.abs	0.374

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
A1CF	6295	12003
AAAS	2965	5701
ACTB	-5057	10683
ADAR	-3971	8398
ADARB1	1506	2971
ADAT1	478	942
ADAT2	6214	11826
ADAT3	-6988	14322
AKT1	-2958	6160
ALKBH8	4880	9252
ALYREF	-6816	14057
ANP32A	7288	14187
APOBEC3B	954	1881
APOBEC3C	7172	13865
AQR	-2059	4245
BCAS2	-879	1798
BMS1	-4769	10122
BOP1	-4381	9269
BUD31	-5011	10569
BYSL	-2637	5477
C1D	3482	6660
C2orf49	-3132	6572
CASC3	-5986	12577
CCAR1	2925	5636
CCNH	5556	10565
CD2BP2	-4125	8720
CDC40	-2131	4412
CDC5L	-2511	5204
CDK7	-5444	11458
CDKAL1	1232	2428
CHERP	-3803	8039
CHTOP	3093	5961
CLNS1A	6527	12457
CLP1	-5588	11776
CNOT1	-2405	4986
CNOT10	-7014	14353
CNOT11	3855	7331
CNOT2	52	107
CNOT3	-6386	13338
CNOT4	-4794	10160
CNOT6	732	1450
CNOT6L	5623	10678
CNOT7	-3082	6430
CNOT8	-6043	12683
CPSF1	-3880	8203
CPSF2	6432	12262
CPSF3	6257	11912
CPSF4	1570	3094
CPSF7	-2243	4652
CRNKL1	-2736	5706
CSNK1D	-5722	12038
CSNK1E	3247	6238
CSTF1	2549	4928
CSTF2	1521	3002
CSTF2T	6871	13172
CSTF3	1177	2311
CTNNBL1	3386	6496
CTU1	-4818	10210
CTU2	-2497	5170
CWC15	-1362	2745
CWC22	-3881	8204
CWC25	-3271	6870
CWC27	-4256	9000
DCAF13	4652	8826
DCP1A	40	88
DCP1B	3617	6898
DCP2	-5125	10825
DCPS	5495	10436
DDX1	-4308	9106
DDX20	-4581	9730
DDX21	-256	530
DDX23	-3721	7859
DDX39A	-6895	14183
DDX39B	-1996	4095
DDX42	5700	10826
DDX46	-967	1974
DDX47	-4068	8593
DDX49	-6809	14045
DDX5	-6665	13814
DDX52	-3894	8227
DDX6	-74	152
DHX15	-1757	3582
DHX16	-2633	5469
DHX37	-5250	11090
DHX38	-6333	13238
DHX9	-4112	8688
DIMT1	2382	4606
DIS3	-1573	3190
DKC1	-1249	2517
DNAJC8	2214	4304
DUS2	3842	7310
EBNA1BP2	-3613	7630
EDC3	-3136	6578
EDC4	-4795	10161
EFTUD2	-3071	6408
EIF4A1	-6995	14329
EIF4A2	5593	10631
EIF4A3	1154	2270
EIF4B	-5898	12396
EIF4E	2473	4766
EIF4G1	-5901	12400
ELAC2	-5264	11117
ELAVL1	-2841	5905
EMG1	7347	14384
ENPP2	6800	13023
ERCC2	-583	1192
ERCC3	-2013	4129
ERI1	-2490	5155
ETF1	-6952	14268
EXOSC1	3486	6667
EXOSC10	-341	697
EXOSC2	3779	7192
EXOSC3	-3453	7270
EXOSC4	3220	6193
EXOSC5	-4766	10117
EXOSC6	-6503	13547
EXOSC7	5196	9819
EXOSC8	472	928
EXOSC9	3293	6333
FAM98B	5786	10984
FAU	-4990	10520
FBL	-1548	3141
FCF1	-2713	5649
FIP1L1	-5876	12362
FTSJ1	-5735	12066
FTSJ3	2052	4006
FUS	7280	14158
FYTTD1	-5952	12505
GAR1	-3015	6286
GCFC2	1481	2925
GEMIN2	6729	12880
GEMIN4	4278	8116
GEMIN5	-2043	4207
GEMIN6	5443	10338
GEMIN7	5050	9555
GEMIN8	928	1822
GLE1	2507	4850
GNL3	-5332	11243
GPKOW	3887	7385
GPRC5A	-5847	12295
GSPT1	-6825	14070
GTF2F1	-3103	6481
GTF2F2	4556	8650
GTF2H1	-5744	12095
GTF2H2	5321	10066
GTF2H3	6024	11478
GTF2H4	-406	824
GTF2H5	4373	8306
GTPBP3	3375	6478
HBS1L	2038	3975
HEATR1	-1324	2664
HNRNPA0	5448	10347
HNRNPA1	-1795	3661
HNRNPA2B1	-6445	13444
HNRNPA3	-6510	13557
HNRNPC	1814	3563
HNRNPD	3107	5989
HNRNPF	-6735	13925
HNRNPH1	3111	5994
HNRNPH2	2555	4938
HNRNPK	-2808	5839
HNRNPL	-4046	8548
HNRNPM	-6829	14075
HNRNPR	1444	2866
HNRNPU	-3716	7853
HNRNPUL1	-1055	2155
HSD17B10	-4604	9788
HSPA1A	1835	3603
HSPA8	-4654	9895
HSPB1	-3343	7039
IGF2	7375	14477
IGF2BP1	-4754	10096
IGF2BP2	-2324	4823
IGF2BP3	36	80
IMP3	-4633	9837
IMP4	-4940	10435
ISG20L2	-3623	7668
ISY1	-2774	5777
KHSRP	-994	2029
KRR1	924	1808
LAGE3	2937	5651
LAS1L	7022	13502
LCMT2	4904	9296
LSM1	-4814	10205
LSM10	-1755	3579
LSM11	5855	11120
LSM2	1691	3315
LSM3	5148	9728
LSM4	6899	13220
LSM5	5261	9948
LSM6	5218	9857
LSM7	-3745	7902
LSM8	5399	10223
LTV1	-5474	11539
MAGOH	-969	1976
MAGOHB	5814	11039
MAPK11	251	492
MAPK14	2269	4391
MAPKAPK2	-6461	13468
METTL1	1104	2167
METTL14	4585	8707
METTL3	4870	9236
MNAT1	-205	420
MPHOSPH10	-6827	14072
MPHOSPH6	5619	10672
MRM1	1041	2042
MRM2	-777	1566
MRM3	2765	5331
MT-ATP6	6186	11770
MT-ATP8	6710	12839
MT-CO1	6493	12380
MT-CO2	716	1414
MT-CO3	7316	14274
MT-CYB	7213	13980
MT-ND1	-4361	9229
MT-ND2	-1660	3387
MT-ND3	3491	6674
MT-ND4	3146	6063
MT-ND4L	1652	3253
MT-ND5	3335	6406
MT-ND6	3010	5803
MTERF4	6222	11841
MTO1	-5079	10728
MYC	1892	3708
NAT10	3342	6419
NCBP1	-2151	4458
NCBP2	6823	13081
NCL	-1840	3770
NDC1	-1490	3023
NHP2	-4261	9010
NIP7	-2165	4480
NOB1	-3772	7960
NOC4L	-1552	3148
NOL11	4020	7634
NOL12	-3773	7961
NOL6	1999	3901
NOL9	-4954	10455
NOP10	-4958	10460
NOP14	-5209	11001
NOP2	-3859	8162
NOP56	-1145	2332
NOP58	5612	10662
NSUN2	-5750	12104
NSUN4	4005	7610
NSUN6	1776	3477
NT5C3B	-4014	8490
NUDT21	2243	4345
NUP107	6076	11561
NUP133	1362	2708
NUP153	2712	5230
NUP155	4796	9102
NUP160	-329	683
NUP188	-4991	10521
NUP205	-5275	11144
NUP210	6802	13025
NUP214	-1926	3957
NUP35	5982	11387
NUP37	7100	13706
NUP43	2808	5410
NUP50	-4733	10047
NUP54	3310	6371
NUP58	2380	4603
NUP62	-299	618
NUP85	4178	7946
NUP88	-4777	10134
NUP93	5831	11067
NUP98	-3764	7940
NXF1	-6277	13130
NXT1	-2092	4313
OSGEP	-368	753
PABPC1	-3543	7490
PABPN1	-2037	4195
PAIP1	377	743
PAN2	7162	13842
PAN3	-1113	2266
PAPOLA	-3183	6675
PARN	-4578	9715
PATL1	-6707	13883
PCBP1	-3633	7689
PCBP2	974	1919
PCF11	-4093	8648
PDCD11	3334	6405
PDCD7	-1301	2613
PELP1	-2894	6020
PES1	-3505	7405
PHAX	-5719	12034
PHF5A	-729	1469
PLRG1	-1743	3554
PNO1	-5758	12126
PNRC2	5595	10635
POLDIP3	1421	2834
POLR2A	2705	5219
POLR2B	-3699	7815
POLR2C	-3425	7212
POLR2D	2418	4674
POLR2E	-4667	9916
POLR2F	-5283	11158
POLR2G	2003	3910
POLR2H	-3593	7590
POLR2I	4594	8717
POLR2J	-603	1234
POLR2K	5962	11350
POLR2L	-5471	11530
POM121	-6353	13281
POM121C	-6045	12687
POP1	-3098	6469
POP4	-42	75
POP5	2364	4573
POP7	-1753	3576
PPIE	1333	2651
PPIH	-247	505
PPIL1	-4712	10001
PPIL3	5149	9734
PPIL4	2522	4884
PPIL6	1052	2058
PPP2CA	-5168	10917
PPP2R1A	-4744	10064
PPP2R2A	5688	10808
PPWD1	3615	6894
PQBP1	-4220	8917
PRCC	-6133	12846
PRKCA	2439	4709
PRKCD	-5638	11872
PRMT5	-1166	2371
PRPF19	2734	5278
PRPF3	-5593	11786
PRPF31	2039	3976
PRPF38A	-1785	3638
PRPF4	2278	4407
PRPF40A	-4000	8463
PRPF6	3945	7488
PRPF8	-4723	10028
PSMA1	-5730	12052
PSMA2	-5801	12203
PSMA3	-3078	6422
PSMA4	-4211	8902
PSMA5	-2715	5657
PSMA6	-126	261
PSMA7	-892	1820
PSMB1	1054	2062
PSMB10	423	838
PSMB2	1876	3678
PSMB3	-1915	3928
PSMB4	-1144	2330
PSMB5	-742	1484
PSMB6	-4888	10326
PSMB7	-4372	9253
PSMB9	5491	10430
PSMC1	-5564	11724
PSMC2	-2389	4948
PSMC3	-1509	3070
PSMC4	-4808	10196
PSMC5	-4091	8646
PSMC6	-4878	10307
PSMD1	-5351	11280
PSMD10	4933	9356
PSMD11	-432	879
PSMD12	4303	8163
PSMD13	-2577	5353
PSMD14	5974	11371
PSMD2	-6435	13423
PSMD3	-5535	11655
PSMD4	4567	8670
PSMD5	5116	9676
PSMD6	-5951	12502
PSMD7	4942	9371
PSMD8	-2928	6091
PSMD9	-4638	9853
PSME1	-2348	4861
PSME2	-5481	11555
PSME3	-3813	8052
PSME4	-6450	13450
PSMF1	-6663	13810
PTBP1	-6035	12672
PUF60	-5927	12445
PUS1	3715	7076
PUS3	4248	8071
PUS7	2099	4098
PWP2	-2005	4115
QTRT1	5195	9816
QTRT2	4536	8612
RAE1	4394	8335
RAN	-6476	13497
RANBP2	-4	9
RBM17	-3092	6454
RBM22	-3875	8191
RBM28	771	1540
RBM5	5541	10543
RBM8A	-1583	3215
RBMX	-5221	11027
RCL1	-942	1910
RIOK1	2711	5229
RIOK2	-4018	8498
RIOK3	-6332	13237
RNGTT	-4400	9314
RNMT	4440	8428
RNPC3	3974	7540
RNPS1	-6938	14245
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPP14	1309	2606
RPP30	1439	2860
RPP38	1564	3081
RPP40	1770	3469
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
RRP1	-5133	10838
RRP36	-6354	13283
RRP7A	2006	3915
RRP9	-2591	5388
RTCB	-5521	11630
SARNP	-3109	6495
SART1	-4784	10145
SEC13	-6812	14049
SEH1L	-4472	9474
SEM1	-3130	6566
SENP3	-1399	2810
SET	2106	4107
SF1	-4554	9656
SF3A1	-4178	8834
SF3A2	-3293	6927
SF3A3	-3033	6319
SF3B1	-343	700
SF3B2	-1718	3509
SF3B3	-4118	8702
SF3B4	-2942	6117
SF3B5	-4294	9077
SF3B6	5469	10382
SKIV2L	4599	8733
SLBP	-6130	12841
SLU7	281	550
SMG1	-2778	5781
SMG5	-654	1338
SMG6	-1323	2663
SMG7	-2718	5661
SMG8	-3868	8180
SMG9	3998	7594
SMN1	-3422	7209
SMNDC1	-978	1991
SNRNP200	-1880	3855
SNRNP25	217	423
SNRNP27	2043	3984
SNRNP35	7126	13772
SNRNP40	-5200	10989
SNRNP48	-6317	13211
SNRNP70	-3471	7324
SNRPA	-6516	13573
SNRPA1	-6983	14316
SNRPB	-1707	3491
SNRPB2	572	1116
SNRPC	686	1350
SNRPD1	5905	11223
SNRPD2	-3171	6642
SNRPD3	-5999	12606
SNRPE	3034	5846
SNRPF	2328	4505
SNRPG	-99	202
SNRPN	623	1217
SNU13	-129	265
SNUPN	-1386	2783
SNW1	-5581	11762
SRRM1	-354	723
SRRM2	-5973	12548
SRRT	-6216	13010
SRSF1	-5478	11549
SRSF10	-4662	9910
SRSF11	-1739	3545
SRSF2	-660	1345
SRSF3	-5244	11078
SRSF4	-6822	14066
SRSF5	6261	11918
SRSF6	6395	12195
SRSF7	2693	5205
SRSF9	-5148	10875
SUGP1	1250	2473
SUPT5H	-5767	12140
SYF2	-6169	12922
SYMPK	-77	157
TBL3	-794	1617
TEX10	-4283	9059
TFB1M	518	1025
TFIP11	-1238	2500
TGS1	2148	4181
THADA	2501	4833
THG1L	1859	3649
THOC1	221	431
THOC2	-1832	3745
THOC3	2285	4422
THOC5	-3719	7857
THOC6	3050	5874
THOC7	1544	3048
THUMPD1	-270	553
TNFSF13	-1035	2105
TNKS1BP1	2031	3960
TNPO1	-6263	13094
TP53RK	-693	1401
TPR	565	1105
TPRKB	2341	4523
TRA2B	-1257	2539
TRDMT1	4998	9466
TRIT1	156	307
TRMT1	-362	736
TRMT10A	-514	1037
TRMT10C	4994	9461
TRMT11	5691	10814
TRMT112	-3869	8181
TRMT12	2539	4906
TRMT13	2920	5627
TRMT44	-4221	8918
TRMT5	6848	13123
TRMT6	-2889	6009
TRMT61A	-644	1311
TRMT61B	3833	7299
TRMU	-5863	12337
TRNT1	3774	7184
TSEN15	6489	12375
TSEN2	3158	6086
TSEN34	469	923
TSEN54	102	200
TSR1	-851	1732
TSR3	-466	947
TTC37	3159	6087
TXNL4A	-2705	5625
TYW1	-5525	11638
TYW3	-105	215
TYW5	-351	716
U2AF1	-2991	6240
U2AF1L4	2349	4541
U2AF2	-987	2011
U2SURP	2650	5123
UBA52	-5068	10707
UBB	-4263	9013
UBC	779	1551
UPF1	-4700	9973
UPF2	-3830	8093
UPF3A	-6189	12957
UPF3B	2326	4503
URM1	1139	2239
USP39	-5721	12036
UTP11	-1337	2685
UTP14A	-5799	12194
UTP14C	-6243	13057
UTP15	-2509	5201
UTP18	-4476	9483
UTP20	-2811	5845
UTP3	4280	8119
UTP4	-6111	12808
UTP6	-1836	3755
WBP11	-1682	3429
WBP4	-2099	4338
WDR12	3814	7261
WDR18	2127	4149
WDR3	5692	10815
WDR33	-4359	9227
WDR36	5735	10892
WDR4	-1153	2350
WDR43	-4193	8863
WDR46	4709	8939
WDR61	452	889
WDR75	3573	6819
WDR77	1552	3057
WTAP	-2646	5502
XAB2	4040	7659
XPO1	-1864	3824
XPOT	-6616	13721
XRN1	-3316	6977
XRN2	-3427	7216
YBX1	-5615	11834
YWHAB	2082	4062
YWHAZ	-885	1810
ZBTB8OS	-2366	4904
ZC3H11A	394	773
ZCCHC11	-659	1344
ZCCHC6	-4631	9834
ZCRB1	4731	8981
ZFP36	-6509	13556
ZFP36L1	-6818	14059
ZMAT5	-2710	5635
ZNF473	1958	3820
ZRSR2	-4009	8485

---

---

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

metric	value
setSize	111
pMANOVA	5.72e-11
p.adjustMANOVA	1.92e-09
s.dist	0.374
s.x	-0.364
s.abs	-0.087
p.x	3.73e-11
p.abs	0.114

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
CASC3	-5986	12577
DCP1A	40	88
EIF4A3	1154	2270
EIF4G1	-5901	12400
ETF1	-6952	14268
FAU	-4990	10520
GSPT1	-6825	14070
MAGOH	-969	1976
MAGOHB	5814	11039
NCBP1	-2151	4458
NCBP2	6823	13081
PABPC1	-3543	7490
PNRC2	5595	10635
PPP2CA	-5168	10917
PPP2R1A	-4744	10064
PPP2R2A	5688	10808
RBM8A	-1583	3215
RNPS1	-6938	14245
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
SMG1	-2778	5781
SMG5	-654	1338
SMG6	-1323	2663
SMG7	-2718	5661
SMG8	-3868	8180
SMG9	3998	7594
UBA52	-5068	10707
UPF1	-4700	9973
UPF2	-3830	8093
UPF3A	-6189	12957
UPF3B	2326	4503

---

---

Nonsense-Mediated Decay (NMD)

Nonsense-Mediated Decay (NMD)

metric	value
setSize	111
pMANOVA	5.72e-11
p.adjustMANOVA	1.92e-09
s.dist	0.374
s.x	-0.364
s.abs	-0.087
p.x	3.73e-11
p.abs	0.114

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
CASC3	-5986	12577
DCP1A	40	88
EIF4A3	1154	2270
EIF4G1	-5901	12400
ETF1	-6952	14268
FAU	-4990	10520
GSPT1	-6825	14070
MAGOH	-969	1976
MAGOHB	5814	11039
NCBP1	-2151	4458
NCBP2	6823	13081
PABPC1	-3543	7490
PNRC2	5595	10635
PPP2CA	-5168	10917
PPP2R1A	-4744	10064
PPP2R2A	5688	10808
RBM8A	-1583	3215
RNPS1	-6938	14245
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
SMG1	-2778	5781
SMG5	-654	1338
SMG6	-1323	2663
SMG7	-2718	5661
SMG8	-3868	8180
SMG9	3998	7594
UBA52	-5068	10707
UPF1	-4700	9973
UPF2	-3830	8093
UPF3A	-6189	12957
UPF3B	2326	4503

---

---

Major pathway of rRNA processing in the nucleolus and cytosol

Major pathway of rRNA processing in the nucleolus and cytosol

metric	value
setSize	174
pMANOVA	1.64e-10
p.adjustMANOVA	5.38e-09
s.dist	0.292
s.x	-0.28
s.abs	-0.0821
p.x	1.91e-10
p.abs	0.0624

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
BMS1	-4769	10122
BOP1	-4381	9269
BYSL	-2637	5477
C1D	3482	6660
CSNK1D	-5722	12038
CSNK1E	3247	6238
DCAF13	4652	8826
DDX21	-256	530
DDX47	-4068	8593
DDX49	-6809	14045
DDX52	-3894	8227
DHX37	-5250	11090
DIS3	-1573	3190
EBNA1BP2	-3613	7630
EMG1	7347	14384
ERI1	-2490	5155
EXOSC1	3486	6667
EXOSC10	-341	697
EXOSC2	3779	7192
EXOSC3	-3453	7270
EXOSC4	3220	6193
EXOSC5	-4766	10117
EXOSC6	-6503	13547
EXOSC7	5196	9819
EXOSC8	472	928
EXOSC9	3293	6333
FAU	-4990	10520
FBL	-1548	3141
FCF1	-2713	5649
FTSJ3	2052	4006
GNL3	-5332	11243
HEATR1	-1324	2664
IMP3	-4633	9837
IMP4	-4940	10435
ISG20L2	-3623	7668
KRR1	924	1808
LAS1L	7022	13502
LTV1	-5474	11539
MPHOSPH10	-6827	14072
MPHOSPH6	5619	10672
NCL	-1840	3770
NIP7	-2165	4480
NOB1	-3772	7960
NOC4L	-1552	3148
NOL11	4020	7634
NOL12	-3773	7961
NOL6	1999	3901
NOL9	-4954	10455
NOP14	-5209	11001
NOP56	-1145	2332
NOP58	5612	10662
PDCD11	3334	6405
PELP1	-2894	6020
PES1	-3505	7405
PNO1	-5758	12126
PWP2	-2005	4115
RBM28	771	1540
RCL1	-942	1910
RIOK1	2711	5229
RIOK2	-4018	8498
RIOK3	-6332	13237
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPP14	1309	2606
RPP30	1439	2860
RPP38	1564	3081
RPP40	1770	3469
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
RRP1	-5133	10838
RRP36	-6354	13283
RRP7A	2006	3915
RRP9	-2591	5388
SENP3	-1399	2810
SNU13	-129	265
TBL3	-794	1617
TEX10	-4283	9059
TSR1	-851	1732
UBA52	-5068	10707
UTP11	-1337	2685
UTP14A	-5799	12194
UTP14C	-6243	13057
UTP15	-2509	5201
UTP18	-4476	9483
UTP20	-2811	5845
UTP3	4280	8119
UTP4	-6111	12808
UTP6	-1836	3755
WDR12	3814	7261
WDR18	2127	4149
WDR3	5692	10815
WDR36	5735	10892
WDR43	-4193	8863
WDR46	4709	8939
WDR75	3573	6819
XRN2	-3427	7216

---

---

SARS-CoV Infections

SARS-CoV Infections

metric	value
setSize	144
pMANOVA	1.93e-10
p.adjustMANOVA	6.17e-09
s.dist	0.327
s.x	-0.312
s.abs	0.0963
p.x	1.05e-10
p.abs	0.0464

Top 20 genes

Gene	x	abs
CANX	-7092	14462
MAGT1	-7045	14398
MAP1LC3B	-7040	14388
RPN1	-7013	14350
CTSL	-6951	14263
ATP1B3	-6941	14249
ST3GAL4	-6801	14033
STT3A	-6796	14026
ATP1A1	-6777	13992
ST6GALNAC4	-6726	13912
VCP	-6720	13902
FURIN	-6683	13851
DDX5	-6665	13814
ATP1B1	-6624	13734
CHMP4C	-6557	13640
VHL	-6491	13531
KEAP1	-6482	13510
BRD4	-6479	13501
DDOST	-6429	13410
MGAT1	-6401	13371

Click HERE to show all gene set members

All member genes

	x	abs
ACE2	2757	5319
AP2A1	-1902	3903
AP2A2	-3499	7391
AP2B1	2029	3955
AP2M1	-4603	9787
AP2S1	-2922	6073
ARID4A	-156	323
ARID4B	480	945
ATP1A1	-6777	13992
ATP1A3	-1706	3489
ATP1A4	412	810
ATP1B1	-6624	13734
ATP1B2	-3692	7805
ATP1B3	-6941	14249
BECN1	-2900	6036
BRD4	-6479	13501
BRMS1	-6309	13195
CANX	-7092	14462
CHD3	-1321	2661
CHD4	-4830	10236
CHMP2A	-1088	2222
CHMP2B	-878	1797
CHMP3	1229	2417
CHMP4A	909	1779
CHMP4B	-5021	10594
CHMP4C	-6557	13640
CHMP6	5904	11222
CHMP7	2690	5197
COMT	2597	5019
CRBN	-1928	3959
CSNK1A1	-5349	11277
CTSL	-6951	14263
CUL3	-3056	6363
CYSLTR1	2493	4813
DAD1	-6240	13053
DDOST	-6429	13410
DDX5	-6665	13814
EDEM2	-5520	11628
FKBP1A	-5189	10960
FKBP4	-5807	12213
FNTA	-6282	13142
FNTB	-2551	5296
FURIN	-6683	13851
FUT8	-5134	10839
FXYD1	-2847	5919
FXYD2	-5865	12339
GALNT1	-816	1659
GANAB	2813	5417
GATAD2A	-4108	8682
GATAD2B	-1092	2228
GSK3A	-3684	7787
GSK3B	-5101	10767
HDAC1	-2676	5563
HDAC2	-338	693
HMG20B	-3184	6676
HSP90AA1	-1030	2096
HSP90AB1	-4426	9363
IFNAR1	4161	7910
IFNAR2	-2313	4798
IFNGR1	1624	3204
IFNGR2	997	1962
IL1R1	6510	12430
IL6R	-4943	10440
IMPDH1	-1807	3690
IMPDH2	4910	9308
ITGB1	-4145	8760
JAK1	-4963	10468
JAK2	-2719	5664
JAK3	7326	14295
KDM1A	4224	8018
KEAP1	-6482	13510
MAGT1	-7045	14398
MAN1B1	-3561	7534
MAN2A1	-1040	2117
MAP1LC3B	-7040	14388
MBD3	-4543	9635
MGAT1	-6401	13371
MGAT2	-3327	7002
MGAT4A	-5018	10584
MGAT4B	-6279	13132
MGAT4C	1714	3364
MGAT5	-5854	12324
MOGS	-2275	4728
MTA1	1810	3553
MTA2	-5619	11843
MTA3	6411	12223
NFE2L2	-2108	4363
NR3C1	-4005	8476
PARP10	5859	11125
PARP14	5386	10194
PARP16	-3842	8129
PARP4	462	908
PARP6	-1567	3181
PARP8	3263	6264
PARP9	6988	13424
PHF21A	-1078	2202
PIK3C3	-5220	11026
PIK3R4	1132	2219
PRKCSH	-5934	12463
PRMT1	-4281	9055
PTGES3	3734	7103
RB1	470	925
RBBP4	-3297	6938
RBBP7	5134	9712
RBX1	-3714	7850
RCOR1	-3493	7376
REST	-593	1214
RIPK1	-2886	6000
ROCK1	-3594	7591
ROCK2	-2772	5775
RPN1	-7013	14350
RPN2	-6193	12964
RPS27A	-2773	5776
SAP18	-3349	7051
SAP30	-5230	11054
SAP30L	-3887	8212
SIGMAR1	753	1508
SRPK1	3007	5798
SRPK2	-1905	3907
ST3GAL1	-5905	12408
ST3GAL2	-4518	9594
ST3GAL3	5918	11257
ST3GAL4	-6801	14033
ST6GAL1	-1828	3739
ST6GALNAC4	-6726	13912
STAT2	76	146
STT3A	-6796	14026
SUDS3	-2287	4748
SUMO1	3308	6365
TBK1	-5169	10919
TLR9	-2371	4913
TMPRSS2	1456	2886
TUBB	5125	9694
TUSC3	-1219	2465
TYK2	5066	9579
UBA52	-5068	10707
UBB	-4263	9013
UBC	779	1551
UBE2I	-1318	2653
UVRAG	-6290	13151
VCP	-6720	13902
VEGFA	-4456	9433
VHL	-6491	13531
ZCRB1	4731	8981

---

---

Selenocysteine synthesis

Selenocysteine synthesis

metric	value
setSize	89
pMANOVA	2.72e-10
p.adjustMANOVA	8.3e-09
s.dist	0.402
s.x	-0.375
s.abs	-0.144
p.x	1e-09
p.abs	0.0189

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
EEFSEC	3653	6962
FAU	-4990	10520
PSTK	-1545	3136
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
SECISBP2	-410	831
SEPHS2	-6447	13446
SEPSECS	6852	13129
UBA52	-5068	10707

---

---

Eukaryotic Translation Termination

Eukaryotic Translation Termination

metric	value
setSize	89
pMANOVA	2.77e-10
p.adjustMANOVA	8.3e-09
s.dist	0.402
s.x	-0.387
s.abs	-0.11
p.x	2.8e-10
p.abs	0.0725

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
APEH	4698	8922
ETF1	-6952	14268
FAU	-4990	10520
GSPT1	-6825	14070
N6AMT1	7144	13806
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
TRMT112	-3869	8181
UBA52	-5068	10707

---

---

Signaling by Receptor Tyrosine Kinases

Signaling by Receptor Tyrosine Kinases

metric	value
setSize	405
pMANOVA	2.77e-10
p.adjustMANOVA	8.3e-09
s.dist	0.196
s.x	-0.179
s.abs	0.0795
p.x	7.81e-10
p.abs	0.00632

Top 20 genes

Gene	x	abs
ATP6V0B	-7064	14422
PGF	-7053	14409
SHB	-7035	14382
ATP6V0A1	-6979	14310
BCAR1	-6926	14233
ATP6V1D	-6922	14228
SHC1	-6910	14209
ATP6V0D1	-6908	14206
ATP6V0A2	-6880	14162
MET	-6878	14159
RANBP9	-6871	14151
VGF	-6864	14140
HNRNPM	-6829	14075
PDGFRB	-6820	14062
TRIB3	-6798	14029
PTPN3	-6738	13930
HNRNPF	-6735	13925
FURIN	-6683	13851
FOSL1	-6672	13826
ATP6V0E1	-6622	13731

Click HERE to show all gene set members

All member genes

	x	abs
AAMP	-5076	10725
ABI1	-4478	9492
ABI2	-1197	2431
ADAM10	-2671	5549
ADAM17	-5836	12276
ADAP1	-1403	2817
ADORA2A	5330	10081
AHCYL1	4874	9245
AKT1	-2958	6160
AKT2	-1946	3993
ANOS1	-3087	6441
AP2A1	-1902	3903
AP2A2	-3499	7391
AP2B1	2029	3955
AP2M1	-4603	9787
AP2S1	-2922	6073
APH1A	619	1209
APH1B	6168	11741
APOE	-3670	7759
ARC	-2587	5378
AREG	-4847	10258
ARF6	-5404	11385
ARHGEF7	-2913	6055
ATF1	-4925	10407
ATF2	-6175	12933
ATP6AP1	-6235	13046
ATP6V0A1	-6979	14310
ATP6V0A2	-6880	14162
ATP6V0B	-7064	14422
ATP6V0C	-6086	12764
ATP6V0D1	-6908	14206
ATP6V0D2	747	1494
ATP6V0E1	-6622	13731
ATP6V0E2	5683	10798
ATP6V1A	-3777	7965
ATP6V1B1	4549	8635
ATP6V1B2	-5574	11744
ATP6V1C1	-4946	10444
ATP6V1C2	-5929	12453
ATP6V1D	-6922	14228
ATP6V1E1	-6271	13114
ATP6V1E2	-534	1090
ATP6V1F	-868	1771
ATP6V1G1	-5352	11283
ATP6V1G2	690	1360
ATP6V1H	-4423	9358
AXL	-2605	5419
BAIAP2	-637	1295
BAX	4757	9026
BCAR1	-6926	14233
BRAF	-4749	10077
BRK1	-5431	11428
CALM1	-655	1340
CBL	-5708	12008
CDC37	-5178	10941
CDC42	-2172	4489
CDK5	-1352	2721
CDK5R1	-157	326
CHD4	-4830	10236
CHEK1	4365	8292
CLTA	-6439	13432
CLTC	-6220	13017
COL4A5	6694	12804
COL6A1	7322	14284
COL6A2	3222	6195
COL6A3	2085	4068
COL9A2	7348	14389
COL9A3	7151	13817
CREB1	474	935
CRK	-5650	11901
CRKL	524	1039
CSK	-4113	8692
CTNNA1	-5558	11711
CTNNB1	3272	6288
CTNND1	7129	13781
CUL5	-1229	2485
CYBA	2202	4283
CYFIP1	1939	3785
CYFIP2	6224	11850
DIAPH1	-5806	12211
DLG4	5108	9664
DNAL4	6609	12616
DNM1	6505	12417
DNM2	-6535	13597
DOCK1	3540	6760
DOCK7	3822	7277
DUSP3	-6541	13608
DUSP4	-5977	12556
DUSP6	-3376	7113
DUSP7	-3870	8185
EGFR	-5383	11344
EGR1	-1475	2989
EGR2	-3207	6724
EGR3	-3972	8399
ELK1	-5733	12060
ELMO1	-2779	5782
ELMO2	942	1854
EP300	-6470	13485
EPN1	-737	1478
EPS15	1254	2479
EPS15L1	3478	6655
ERBB2	5534	10533
ERBB3	4249	8072
ERBIN	-2316	4809
EREG	3467	6635
ESRP2	-2361	4883
F3	1642	3237
FER	4431	8408
FES	5506	10476
FGF17	-4015	8493
FGF23	2097	4091
FGF5	342	659
FGFBP3	6730	12881
FGFR1	-6191	12960
FGFR2	6811	13048
FGFR3	-1195	2426
FGFR4	-2795	5810
FGFRL1	-3751	7915
FLRT1	3504	6694
FLRT2	3988	7566
FLRT3	7184	13907
FLT3LG	6000	11436
FLT4	2167	4214
FOS	-5174	10931
FOSB	-6091	12773
FOSL1	-6672	13826
FRS2	-3790	8007
FRS3	2112	4125
FURIN	-6683	13851
FYN	1937	3783
GAB1	1575	3105
GAB2	-4127	8722
GABRB3	1163	2287
GABRG2	2849	5492
GABRG3	-451	919
GALNT3	-3227	6774
GFAP	2552	4934
GGA3	4199	7982
GRAP	-3478	7339
GRB10	-5504	11598
GRB2	-3047	6346
GRB7	-4006	8477
GRIN2B	1330	2648
GTF2F1	-3103	6481
GTF2F2	4556	8650
HBEGF	-4402	9320
HDAC1	-2676	5563
HDAC2	-338	693
HDAC3	38	84
HGFAC	6708	12835
HGS	-4210	8898
HIF1A	-4165	8807
HNRNPA1	-1795	3661
HNRNPF	-6735	13925
HNRNPH1	3111	5994
HNRNPM	-6829	14075
HPN	6820	13075
HRAS	-5543	11673
HSP90AA1	-1030	2096
HSPB1	-3343	7039
ID1	4484	8511
ID2	-282	576
ID3	2220	4312
IGF1R	-2746	5730
IGF2	7375	14477
INSR	-5097	10761
IRS1	3502	6691
IRS2	-5461	11497
ITCH	-6089	12771
ITGA2	-6205	12988
ITGA3	-1662	3390
ITGAV	-4312	9120
ITGB1	-4145	8760
ITPR1	-4321	9146
ITPR2	2257	4366
ITPR3	-6088	12768
JAK2	-2719	5664
JAK3	7326	14295
JUNB	-3526	7447
JUND	4563	8660
JUP	2314	4478
KIDINS220	-6056	12710
KITLG	92	180
KLB	-3807	8045
KRAS	-2044	4210
LAMA1	1285	2553
LAMA3	-5316	11218
LAMA4	790	1568
LAMA5	6638	12680
LAMB1	3783	7198
LAMB2	495	978
LAMB3	-673	1365
LAMC1	-1300	2611
LAMC2	-228	466
LAMC3	1169	2298
LCK	-6250	13069
LRIG1	-6280	13140
LYL1	726	1438
LYN	-3038	6328
MAP2K1	-4120	8704
MAP2K2	-6087	12766
MAP2K5	-2441	5053
MAPK1	-5066	10705
MAPK11	251	492
MAPK12	-5538	11663
MAPK13	-1875	3846
MAPK14	2269	4391
MAPK3	6640	12684
MAPK7	-4382	9270
MAPKAP1	-5936	12466
MAPKAPK2	-6461	13468
MAPKAPK3	-5773	12147
MATK	851	1673
MDK	4615	8761
MEF2A	-3308	6959
MEF2D	-5995	12594
MEMO1	-5843	12288
MET	-6878	14159
MKNK1	-2340	4846
MLST8	1875	3677
MST1	-4720	10022
MST1R	5156	9745
MTOR	-3683	7785
MUC20	-1019	2082
MXD4	-5116	10802
MYC	1892	3708
NAB1	765	1529
NAB2	-6372	13315
NCBP1	-2151	4458
NCBP2	6823	13081
NCF2	-5438	11446
NCK1	1525	3010
NCK2	-3916	8271
NCKAP1	-2788	5794
NCKAP1L	-972	1980
NCOR1	-4374	9256
NCSTN	-554	1137
NEDD4	196	383
NELFB	-2298	4775
NOS3	-4903	10359
NRAS	2310	4465
NRP1	1353	2695
NRP2	-5313	11212
PAG1	2774	5350
PAK1	1031	2021
PAK2	-4957	10458
PCSK5	3449	6597
PCSK6	5326	10075
PDE3B	-5303	11196
PDGFA	-2660	5524
PDGFB	6920	13263
PDGFC	-5072	10716
PDGFRB	-6820	14062
PDPK1	399	782
PGF	-7053	14409
PIK3C3	-5220	11026
PIK3CA	-2813	5849
PIK3CB	-2588	5379
PIK3R1	-4376	9259
PIK3R2	-1355	2728
PIK3R3	-2279	4734
PIK3R4	1132	2219
PLAT	4797	9105
PLCG1	2511	4855
PLG	7380	14495
POLR2A	2705	5219
POLR2B	-3699	7815
POLR2C	-3425	7212
POLR2D	2418	4674
POLR2E	-4667	9916
POLR2F	-5283	11158
POLR2G	2003	3910
POLR2H	-3593	7590
POLR2I	4594	8717
POLR2J	-603	1234
POLR2K	5962	11350
POLR2L	-5471	11530
PPP2CA	-5168	10917
PPP2CB	-4523	9606
PPP2R1A	-4744	10064
PPP2R1B	4614	8759
PPP2R5D	-2117	4385
PRKACA	1736	3407
PRKACB	-1429	2885
PRKCA	2439	4709
PRKCD	-5638	11872
PRKCE	-5510	11606
PRKCZ	-6584	13676
PRR5	-2094	4323
PSEN1	-4938	10427
PSEN2	-2559	5310
PSENEN	-2327	4828
PTBP1	-6035	12672
PTK2	-4346	9198
PTK2B	6809	13043
PTK6	3304	6358
PTPN1	3622	6909
PTPN11	-867	1770
PTPN12	-5326	11236
PTPN18	6851	13128
PTPN2	-3809	8048
PTPN3	-6738	13930
PTPN6	6557	12513
PTPRJ	-6103	12791
PTPRK	-6199	12980
PTPRS	397	779
PTPRU	4441	8430
PXN	2548	4926
RAB4A	-2148	4453
RAB4B	3174	6116
RAC1	44	95
RALA	-6548	13623
RALB	270	524
RALGDS	4617	8765
RANBP10	-1342	2698
RANBP9	-6871	14151
RAP1A	309	604
RAP1B	3577	6830
RAPGEF1	-6586	13680
RASA1	2559	4950
RBFOX2	1286	2561
REST	-593	1214
RHOA	-5294	11182
RICTOR	-2076	4274
RIT1	-5298	11188
RNF41	6188	11780
ROCK1	-3594	7591
ROCK2	-2772	5775
RPS27A	-2773	5776
RPS6KA1	-3857	8159
RPS6KA2	-1149	2339
RPS6KA3	-3030	6316
RPS6KA5	3086	5949
RRAD	-5988	12580
SGK1	865	1698
SH2B2	1149	2259
SH2B3	-4752	10091
SH2D2A	5820	11047
SH3GL1	-4200	8879
SH3KBP1	-917	1864
SHB	-7035	14382
SHC1	-6910	14209
SHC2	-5479	11550
SHC3	-3782	7979
SIN3A	-5884	12373
SOCS1	5053	9561
SOCS6	-5467	11523
SOS1	-950	1928
SPARC	1607	3167
SPHK1	-3142	6587
SPINT1	-3991	8433
SPINT2	-632	1286
SPP1	-5872	12355
SPRED1	-2574	5348
SPRED2	-2862	5946
SPRY1	-1918	3939
SPRY2	-1990	4083
SRC	3962	7516
SRF	-3090	6447
STAM	5109	9665
STAM2	3080	5933
STAT1	-5668	11938
STAT3	4253	8078
STAT5A	5288	10000
STAT5B	6572	12541
STAT6	-1541	3128
STMN1	2680	5180
STUB1	3373	6475
TAB2	-3878	8201
TCF12	-3164	6626
TCIRG1	180	348
TF	5850	11111
TGFA	-4511	9574
THBS1	5988	11408
THBS2	2512	4856
THBS3	4450	8446
THBS4	7170	13862
THEM4	6080	11571
TIA1	6310	12027
TIAL1	-4432	9377
TIAM1	4452	8451
TLR9	-2371	4913
TNS3	-3893	8224
TNS4	-3726	7866
TPH1	4694	8911
TRIB1	5404	10234
TRIB3	-6798	14029
UBA52	-5068	10707
UBB	-4263	9013
UBC	779	1551
USP8	-2820	5864
VAV2	2817	5425
VAV3	-4642	9861
VEGFA	-4456	9433
VEGFB	-6562	13646
VGF	-6864	14140
VRK3	-1278	2573
WASF1	-5712	12021
WASF2	-3366	7096
WASF3	2619	5070
WWOX	-1477	2994
WWP1	-779	1572
YAP1	2171	4225
YES1	-1340	2690
YWHAB	2082	4062

---

---

Influenza Infection

Influenza Infection

metric	value
setSize	151
pMANOVA	3.58e-10
p.adjustMANOVA	1.05e-08
s.dist	0.31
s.x	-0.309
s.abs	-0.0292
p.x	6.29e-11
p.abs	0.537

Top 20 genes

Gene	x	abs

Click HERE to show all gene set members

All member genes

	x	abs
AAAS	2965	5701
CALR	-7142	14529
CANX	-7092	14462
CLTA	-6439	13432
CLTC	-6220	13017
CPSF4	1570	3094
DNAJC3	-7131	14516
EIF2AK2	2886	5562
FAU	-4990	10520
GRSF1	-4747	10070
GTF2F1	-3103	6481
GTF2F2	4556	8650
HSP90AA1	-1030	2096
HSPA1A	1835	3603
IPO5	-6366	13302
ISG15	-5488	11568
KPNA1	-6701	13876
KPNA2	-4575	9708
KPNA3	-4357	9223
KPNA4	-1701	3478
KPNA5	258	506
KPNB1	-6379	13324
NDC1	-1490	3023
NUP107	6076	11561
NUP133	1362	2708
NUP153	2712	5230
NUP155	4796	9102
NUP160	-329	683
NUP188	-4991	10521
NUP205	-5275	11144
NUP210	6802	13025
NUP214	-1926	3957
NUP35	5982	11387
NUP37	7100	13706
NUP43	2808	5410
NUP50	-4733	10047
NUP54	3310	6371
NUP58	2380	4603
NUP62	-299	618
NUP85	4178	7946
NUP88	-4777	10134
NUP93	5831	11067
NUP98	-3764	7940
PABPN1	-2037	4195
PARP1	2974	5715
POLR2A	2705	5219
POLR2B	-3699	7815
POLR2C	-3425	7212
POLR2D	2418	4674
POLR2E	-4667	9916
POLR2F	-5283	11158
POLR2G	2003	3910
POLR2H	-3593	7590
POLR2I	4594	8717
POLR2J	-603	1234
POLR2K	5962	11350
POLR2L	-5471	11530
POM121	-6353	13281
POM121C	-6045	12687
RAE1	4394	8335
RAN	-6476	13497
RANBP2	-4	9
RPL10	-5026	10608
RPL10A	-2689	5584
RPL11	-5032	10624
RPL12	-983	2000
RPL13	-706	1426
RPL13A	-2872	5970
RPL14	-4978	10500
RPL15	-1313	2637
RPL17	-1119	2280
RPL18	-3961	8381
RPL18A	-2240	4649
RPL19	-5254	11094
RPL21	1385	2755
RPL22	2142	4170
RPL22L1	-214	439
RPL23	-1913	3923
RPL23A	-2692	5592
RPL24	-1804	3686
RPL26	-1747	3560
RPL26L1	-3873	8188
RPL27	-2070	4268
RPL27A	-4297	9081
RPL28	-3546	7500
RPL29	-3450	7265
RPL3	-1165	2369
RPL30	-4081	8630
RPL31	330	638
RPL32	-3448	7263
RPL34	-2974	6203
RPL35	-2849	5927
RPL35A	-4159	8797
RPL36	-3432	7221
RPL36A	2875	5542
RPL36AL	-6981	14313
RPL37	-3413	7194
RPL37A	-2451	5072
RPL38	-1791	3652
RPL39	-2270	4713
RPL4	-2563	5324
RPL41	-2635	5472
RPL5	-495	1001
RPL6	-3843	8132
RPL7	-2984	6223
RPL7A	-2233	4625
RPL8	-3467	7307
RPL9	261	509
RPLP0	-4290	9067
RPLP1	-4391	9291
RPLP2	-2863	5950
RPS10	-3155	6612
RPS11	-4702	9977
RPS12	-4367	9239
RPS13	-2581	5366
RPS14	-3261	6851
RPS15	-5010	10567
RPS15A	-3019	6295
RPS16	-2898	6026
RPS17	-3369	7104
RPS18	-2648	5504
RPS19	-4661	9909
RPS2	-3462	7293
RPS20	-1754	3578
RPS21	-2927	6082
RPS23	-2467	5114
RPS24	-3352	7060
RPS25	-937	1901
RPS26	419	827
RPS27	-152	312
RPS27A	-2773	5776
RPS27L	-3180	6664
RPS28	-4652	9891
RPS29	-3844	8133
RPS3	-2880	5985
RPS3A	-179	369
RPS4X	-3464	7297
RPS4Y1	-2120	4388
RPS5	-4778	10135
RPS6	-2681	5569
RPS7	-5138	10850
RPS8	-1071	2190
RPS9	-4028	8515
RPSA	-3520	7435
SEC13	-6812	14049
SEH1L	-4472	9474
SLC25A6	-3733	7878
TGFB1	-6934	14241
TPR	565	1105
UBA52	-5068	10707
XPO1	-1864	3824

---

---

Transport of small molecules

Transport of small molecules

metric	value
setSize	535
pMANOVA	5.27e-10
p.adjustMANOVA	1.51e-08
s.dist	0.169
s.x	-0.128
s.abs	0.111
p.x	4.55e-07
p.abs	1.35e-05

Top 20 genes

Gene	x	abs
SLC6A12	-7138	14525
SLC2A1	-7130	14515
SLC3A2	-7128	14513
SEL1L	-7124	14508
ATP2A2	-7119	14500
SLC4A2	-7091	14460
AZGP1	-7090	14459
SLC5A3	-7087	14456
SLC17A5	-7072	14434
ATP6V0B	-7064	14422
DERL2	-7046	14399
MAGT1	-7045	14398
RUNX1	-7020	14359
SLC33A1	-7011	14348
STEAP3	-6993	14327
OS9	-6986	14320
ATP6V0A1	-6979	14310
CLCN7	-6975	14303
SLC1A4	-6962	14285
ATP1B3	-6941	14249

Click HERE to show all gene set members

All member genes

	x	abs
A2M	1190	2340
ABCA1	-2289	4752
ABCA10	-1900	3897
ABCA2	5830	11066
ABCA3	3033	5842
ABCA4	138	271
ABCA5	-3440	7239
ABCA6	1075	2114
ABCA7	1307	2604
ABCA9	348	670
ABCB1	-6821	14065
ABCB10	4966	9418
ABCB4	-6800	14032
ABCB6	-2491	5157
ABCB7	-37	64
ABCB8	73	138
ABCB9	1393	2771
ABCC1	-5950	12501
ABCC10	-5440	11451
ABCC11	1235	2434
ABCC2	-6611	13713
ABCC3	6271	11944
ABCC4	-6050	12699
ABCC5	-4923	10405
ABCC6	4285	8124
ABCC9	3136	6037
ABCD1	-6246	13062
ABCD3	-405	821
ABCF1	-5879	12365
ABCG2	-2268	4707
ABCG5	6607	12609
ABCG8	2955	5687
ACO1	6643	12690
ADCY1	4808	9122
ADCY2	-667	1356
ADCY6	-2818	5862
ADCY7	6316	12040
ADCY9	4287	8130
ADD1	-5966	12538
ADD2	3583	6840
ADD3	5685	10801
AFG3L2	-5918	12427
AHCYL2	-3027	6312
AKAP1	350	674
ALAD	6318	12045
ALB	3096	5965
AMN	-881	1802
ANGPTL4	6953	13342
ANGPTL8	5759	10936
ANKH	-2214	4588
ANO10	-2362	4894
ANO3	660	1301
ANO6	-5826	12256
ANO7	3225	6199
ANO8	-168	350
ANO9	3858	7334
AP2A1	-1902	3903
AP2A2	-3499	7391
AP2B1	2029	3955
AP2M1	-4603	9787
AP2S1	-2922	6073
APOA1	6993	13433
APOA2	-6307	13191
APOA4	226	444
APOA5	4116	7816
APOB	-2964	6172
APOBR	-1761	3591
APOC1	746	1491
APOC2	5283	9992
APOC3	7361	14431
APOE	-3670	7759
APOF	-4084	8633
AQP11	4559	8655
AQP3	-6877	14157
AQP6	-530	1080
AQP7	4962	9413
AQP8	-5439	11449
ARL2	5716	10857
ARL2BP	2008	3919
ASIC1	5987	11407
ASIC3	-1710	3495
ASPH	-4305	9100
ATP10A	-5452	11471
ATP10B	633	1240
ATP10D	1678	3294
ATP11A	1486	2935
ATP11B	-2420	5015
ATP11C	-1808	3691
ATP13A1	-6730	13918
ATP13A2	-5321	11229
ATP1A1	-6777	13992
ATP1A3	-1706	3489
ATP1A4	412	810
ATP1B1	-6624	13734
ATP1B2	-3692	7805
ATP1B3	-6941	14249
ATP2A1	4477	8492
ATP2A2	-7119	14500
ATP2B1	-5317	11220
ATP2B2	-1271	2557
ATP2B4	6765	12954
ATP2C1	738	1467
ATP6AP1	-6235	13046
ATP6V0A1	-6979	14310
ATP6V0A2	-6880	14162
ATP6V0B	-7064	14422
ATP6V0C	-6086	12764
ATP6V0D1	-6908	14206
ATP6V0D2	747	1494
ATP6V0E1	-6622	13731
ATP6V0E2	5683	10798
ATP6V1A	-3777	7965
ATP6V1B1	4549	8635
ATP6V1B2	-5574	11744
ATP6V1C1	-4946	10444
ATP6V1C2	-5929	12453
ATP6V1D	-6922	14228
ATP6V1E1	-6271	13114
ATP6V1E2	-534	1090
ATP6V1F	-868	1771
ATP6V1G1	-5352	11283
ATP6V1G2	690	1360
ATP6V1H	-4423	9358
ATP7A	2111	4123
ATP7B	-6074	12740
ATP8A1	5995	11425
ATP8B1	2014	3930
ATP8B2	-6740	13934
ATP8B3	-1158	2356
ATP9A	7207	13965
ATP9B	4824	9145
AZGP1	-7090	14459
BEST1	-4422	9355
BEST4	6068	11546
BMP1	324	626
BSG	-4895	10339
CALM1	-655	1340
CAMK2A	4566	8669
CAMK2D	1711	3358
CAMK2G	2145	4176
CAND1	-1658	3381
CES3	7260	14110
CETP	2836	5470
CIDEC	5540	10542
CLCN2	-4116	8698
CLCN3	-6297	13163
CLCN4	-5598	11792
CLCN5	-4913	10384
CLCN6	3165	6094
CLCN7	-6975	14303
CLIC2	1785	3497
CLTA	-6439	13432
CLTC	-6220	13017
CP	7325	14292
CREB3L3	5999	11433
CTNS	-6067	12728
CUBN	854	1678
CUL1	-4129	8725
CUTC	6805	13036
CYB5R1	-5677	11951
CYB5R2	-765	1534
CYB5R4	-3202	6715
CYB5RL	-1539	3125
CYBRD1	913	1784
CYGB	7221	14010
DERL1	-6423	13398
DERL2	-7046	14399
DMTN	3006	5795
EIF2S1	-5190	10961
EIF2S2	-4458	9437
EIF2S3	-3669	7757
ERLEC1	-6168	12918
ERLIN1	3212	6181
ERLIN2	5405	10235
FBXL5	5669	10775
FGF21	-5017	10580
FKBP1B	6880	13183
FLVCR1	-5183	10949
FTH1	-5419	11406
FTL	-6697	13872
FURIN	-6683	13851
FXYD1	-2847	5919
FXYD2	-5865	12339
GLRX3	-3903	8244
GNAS	459	900
GNB1	-3237	6796
GNB2	-4514	9583
GNB3	-1008	2063
GNB4	1936	3781
GNB5	700	1388
GNG10	6779	12977
GNG4	6164	11731
GNG5	4123	7830
GNG7	4426	8395
HBA1	-3024	6302
HDLBP	-6874	14154
HFE	6292	11997
HMOX1	4592	8715
HMOX2	-4742	10061
IREB2	-2200	4556
KCNJ11	4499	8545
LCAT	-6469	13483
LCN12	4023	7637
LCN15	-740	1482
LCN2	-4096	8658
LDLR	5216	9855
LDLRAP1	1234	2433
LETM1	-5941	12482
LIPA	-3416	7201
LIPC	6782	12986
LIPG	7369	14461
LMF1	5611	10661
LMF2	-3441	7243
LRRC8A	-6858	14125
LRRC8B	3745	7129
LRRC8C	-1082	2208
LRRC8D	3262	6262
LRRC8E	-4728	10038
LSR	-6760	13970
MAGT1	-7045	14398
MBTPS1	-5958	12523
MBTPS2	3687	7019
MCOLN1	-6597	13693
MCU	432	850
MCUB	818	1610
MFSD4B	384	751
MICU1	-2871	5968
MICU2	5884	11176
MICU3	5270	9966
MMGT1	-3233	6784
MRS2	2613	5059
MTTP	6265	11924
MYLIP	-6047	12695
MYO5B	-5	11
NCEH1	-6227	13032
NEDD4L	7233	14037
NEDD8	580	1131
NIPA1	-4536	9625
NIPA2	-6669	13823
NIPAL1	-81	164
NIPAL2	-4860	10281
NIPAL3	4474	8482
NPC1	-5943	12486
NPC2	-6207	12991
NR1H2	193	373
NR1H3	4678	8878
OS9	-6986	14320
OSTM1	-5356	11289
P4HB	-6884	14170
PARL	4472	8480
PCSK5	3449	6597
PCSK6	5326	10075
PCSK9	7381	14502
PDZD11	3385	6494
PEX19	7099	13704
PEX3	3593	6860
PHB	-4920	10399
PHB2	-2481	5140
PLTP	-4883	10314
PMPCA	-2331	4832
PMPCB	5842	11098
PRKACA	1736	3407
PRKACB	-1429	2885
PRKAR1A	4	6
PRKAR1B	-1038	2113
PRKAR2A	-860	1753
PSMA1	-5730	12052
PSMA2	-5801	12203
PSMA3	-3078	6422
PSMA4	-4211	8902
PSMA5	-2715	5657
PSMA6	-126	261
PSMA7	-892	1820
PSMB1	1054	2062
PSMB10	423	838
PSMB2	1876	3678
PSMB3	-1915	3928
PSMB4	-1144	2330
PSMB5	-742	1484
PSMB6	-4888	10326
PSMB7	-4372	9253
PSMB9	5491	10430
PSMC1	-5564	11724
PSMC2	-2389	4948
PSMC3	-1509	3070
PSMC4	-4808	10196
PSMC5	-4091	8646
PSMC6	-4878	10307
PSMD1	-5351	11280
PSMD10	4933	9356
PSMD11	-432	879
PSMD12	4303	8163
PSMD13	-2577	5353
PSMD14	5974	11371
PSMD2	-6435	13423
PSMD3	-5535	11655
PSMD4	4567	8670
PSMD5	5116	9676
PSMD6	-5951	12502
PSMD7	4942	9371
PSMD8	-2928	6091
PSMD9	-4638	9853
PSME1	-2348	4861
PSME2	-5481	11555
PSME3	-3813	8052
PSME4	-6450	13450
PSMF1	-6663	13810
RAB11A	4527	8597
RAB11FIP2	-712	1442
RAF1	-5557	11708
RHBG	6586	12570
RNF185	-6359	13291
RNF5	-6629	13745
RPS27A	-2773	5776
RSC1A1	-188	387
RUNX1	-7020	14359
RYR3	2451	4725
SAR1B	-2973	6198
SCARB1	-3949	8356
SCNN1A	6872	13173
SCNN1D	6512	12435
SEL1L	-7124	14508
SEM1	-3130	6566
SGK1	865	1698
SGK2	-6547	13618
SGK3	-6660	13801
SKP1	-544	1117
SLC11A1	3527	6739
SLC11A2	-3217	6749
SLC12A2	-5278	11147
SLC12A4	-1609	3276
SLC12A5	1045	2048
SLC12A6	-6223	13027
SLC12A7	-6765	13978
SLC13A3	6824	13083
SLC13A5	7039	13529
SLC14A2	-848	1727
SLC15A1	3651	6960
SLC15A2	1189	2338
SLC15A4	2407	4647
SLC16A1	4057	7693
SLC16A10	-5868	12348
SLC16A3	-5037	10630
SLC16A7	569	1113
SLC17A1	6328	12062
SLC17A5	-7072	14434
SLC17A7	248	487
SLC1A2	-4985	10514
SLC1A4	-6962	14285
SLC1A5	-5969	12542
SLC1A6	1489	2942
SLC1A7	-2986	6227
SLC20A1	1772	3471
SLC20A2	-2599	5400
SLC22A1	-2514	5220
SLC22A11	45	97
SLC22A15	-6719	13900
SLC22A16	2697	5211
SLC22A17	3832	7295
SLC22A18	262	512
SLC22A3	-5728	12047
SLC22A4	-2747	5732
SLC22A5	-1944	3989
SLC22A7	7270	14131
SLC24A1	5215	9854
SLC24A4	2892	5578
SLC25A10	1107	2172
SLC25A22	-6177	12936
SLC25A26	-3380	7125
SLC25A29	1225	2413
SLC25A4	-3203	6719
SLC25A5	-4001	8466
SLC25A6	-3733	7878
SLC26A1	-6856	14123
SLC26A11	-5710	12012
SLC26A2	2580	4985
SLC26A3	83	165
SLC26A6	-3127	6561
SLC27A1	5484	10421
SLC27A4	-1101	2241
SLC28A1	2814	5420
SLC28A2	2980	5722
SLC29A1	6260	11917
SLC29A2	5346	10107
SLC29A3	-456	930
SLC29A4	3137	6038
SLC2A1	-7130	14515
SLC2A10	4273	8109
SLC2A11	-3946	8353
SLC2A13	-4648	9877
SLC2A14	4503	8550
SLC2A2	7259	14109
SLC2A3	-1535	3116
SLC2A4	1030	2019
SLC2A6	-1104	2245
SLC2A8	-6375	13319
SLC2A9	-1899	3896
SLC30A1	-6410	13381
SLC30A10	6874	13175
SLC30A2	1818	3567
SLC30A3	4877	9248
SLC30A5	-3771	7959
SLC30A6	4251	8074
SLC30A7	-6817	14058
SLC31A1	-6109	12803
SLC33A1	-7011	14348
SLC34A3	-4411	9335
SLC35A1	3906	7418
SLC35A2	-2730	5685
SLC35A3	4972	9426
SLC35B2	1397	2785
SLC35B3	5383	10191
SLC35B4	5565	10583
SLC35C1	-6667	13821
SLC35D1	3595	6862
SLC35D2	-4538	9628
SLC36A1	-6079	12750
SLC36A4	-2674	5557
SLC38A1	-6099	12783
SLC38A2	-5384	11345
SLC38A3	-3218	6758
SLC38A4	7106	13723
SLC38A5	-4053	8563
SLC39A1	-4765	10116
SLC39A10	7112	13739
SLC39A14	-6749	13945
SLC39A3	3172	6110
SLC39A4	6798	13020
SLC39A5	-3468	7315
SLC39A6	-883	1807
SLC39A7	-6897	14185
SLC39A8	978	1929
SLC3A1	-1764	3595
SLC3A2	-7128	14513
SLC40A1	-2061	4248
SLC41A1	2050	3998
SLC41A2	-4651	9890
SLC43A1	-2176	4501
SLC43A2	-3278	6891
SLC44A1	-2042	4205
SLC44A2	6879	13182
SLC44A3	4670	8864
SLC44A4	-73	151
SLC44A5	2874	5540
SLC45A3	777	1548
SLC46A1	-835	1702
SLC47A1	2119	4136
SLC4A1	141	280
SLC4A2	-7091	14460
SLC4A3	-2735	5700
SLC4A5	1807	3549
SLC4A7	3094	5963
SLC4A8	822	1616
SLC50A1	-1505	3058
SLC5A11	-2333	4837
SLC5A2	3524	6735
SLC5A3	-7087	14456
SLC5A6	-5696	11982
SLC5A9	7133	13788
SLC6A11	-2353	4870
SLC6A12	-7138	14525
SLC6A14	695	1374
SLC6A2	-6609	13711
SLC6A20	876	1719
SLC6A6	-6842	14092
SLC6A9	-6424	13399
SLC7A1	-3181	6668
SLC7A10	-5071	10715
SLC7A11	6137	11686
SLC7A2	-5658	11923
SLC7A3	6226	11852
SLC7A5	-5500	11592
SLC7A6	-6794	14024
SLC7A7	2968	5704
SLC7A9	2093	4084
SLC8B1	4519	8584
SLC9A1	-6394	13358
SLC9A4	3848	7317
SLC9A5	1017	2001
SLC9A6	-5075	10721
SLC9A7	3040	5856
SLC9A8	2525	4887
SLC9B1	-1425	2876
SLC9B2	-1574	3192
SLCO1A2	2074	4048
SLCO1B3	4370	8303
SLCO2A1	4980	9440
SLCO2B1	6904	13235
SLCO4A1	-5739	12084
SLCO4C1	5675	10785
SMDT1	-2400	4971
SOAT1	-2594	5394
SOAT2	-6413	13385
SPG7	3037	5853
STEAP2	-4854	10271
STEAP3	-6993	14327
STOM	-1523	3093
STOML2	-2751	5739
TCIRG1	180	348
TF	5850	11111
TFR2	7088	13670
TFRC	-6637	13755
TPCN1	-1096	2232
TPCN2	4830	9157
TRPC1	3602	6877
TRPC4AP	-2573	5347
TRPM4	6005	11442
TRPM6	3306	6362
TRPM7	-5734	12063
TRPV1	454	891
TRPV2	30	69
TRPV3	1488	2941
TRPV4	2337	4517
TSC22D3	4770	9049
TTYH1	4435	8417
TTYH2	3949	7495
TTYH3	-5319	11226
TUSC3	-1219	2465
UBA52	-5068	10707
UBB	-4263	9013
UBC	779	1551
UNC79	-697	1413
UNC80	3953	7499
VCP	-6720	13902
VDAC1	-1027	2092
VDAC2	-2869	5966
VDAC3	-273	561
VLDLR	3001	5770
WNK1	-527	1076
WNK2	3585	6844
WNK3	1427	2842
WNK4	-1776	3620
WWP1	-779	1572
YME1L1	-5518	11621
ZDHHC8	-283	577

---

---

Transport to the Golgi and subsequent modification

Transport to the Golgi and subsequent modification

metric	value
setSize	146
pMANOVA	9.25e-10
p.adjustMANOVA	2.6e-08
s.dist	0.314
s.x	-0.286
s.abs	0.129
p.x	2.45e-09
p.abs	0.00721

Top 20 genes

Gene	x	abs
SEC24D	-7134	14520
TMED2	-7071	14433
MCFD2	-7065	14425
MIA3	-7049	14404
FUT3	-7001	14335
TMED7	-6933	14240
SEC24A	-6839	14088
SEC13	-6812	14049
ST3GAL4	-6801	14033
ANK2	-6778	13993
TMEM115	-6764	13976
TRAPPC10	-6585	13677
LMAN2	-6558	13641
COPB2	-6532	13594
CD55	-6517	13575
PPP6R1	-6511	13558
ARCN1	-6505	13549
TMED9	-6502	13545
MAN1A2	-6460	13466
MGAT1	-6401	13371

Click HERE to show all gene set members

All member genes

	x	abs
ACTR10	5570	10590
ACTR1A	-5162	10903
ANK1	-4656	9901
ANK2	-6778	13993
ANK3	303	591
ANKRD28	4146	7882
ARCN1	-6505	13549
AREG	-4847	10258
ARF1	-6021	12642
ARF3	-2430	5040
ARF4	-5812	12225
ARF5	4743	8998
ARFGAP1	-1587	3224
ARFGAP2	1283	2547
ARFGAP3	-4817	10209
B4GALT1	-262	540
B4GALT2	-2487	5152
B4GALT3	-4852	10265
B4GALT4	2602	5027
B4GALT5	6846	13121
B4GALT6	2881	5555
BET1	457	896
BET1L	3487	6669
CAPZA1	-4855	10272
CAPZA2	-1549	3143
CAPZB	-1169	2376
CD55	-6517	13575
CD59	-3245	6818
CHST10	6919	13262
CNIH1	212	416
CNIH3	-1958	4025
COG1	4586	8708
COG2	-4254	8997
COG3	-5948	12497
COG4	1972	3852
COG5	-3964	8389
COG6	3264	6266
COG7	4792	9093
COG8	6745	12910
COL7A1	5362	10152
COPA	-3958	8376
COPB1	-4098	8664
COPB2	-6532	13594
COPE	-5961	12527
COPG1	-5135	10840
COPG2	6142	11691
COPZ1	782	1554
CSNK1D	-5722	12038
CTSC	-4446	9398
DCTN1	-1635	3338
DCTN2	-3957	8375
DCTN3	1457	2887
DCTN4	-1937	3979
DCTN5	-3634	7690
DCTN6	-318	666
DYNC1H1	-3614	7639
DYNC1I2	-2780	5783
DYNC1LI1	-2519	5237
DYNC1LI2	-3897	8235
DYNLL1	2509	4853
DYNLL2	6044	11507
F5	831	1638
F8	735	1460
FUCA1	2696	5210
FUT3	-7001	14335
FUT8	-5134	10839
GBF1	-4981	10507
GOLGA2	-5310	11209
GOLGB1	-3498	7386
GORASP1	1903	3727
GOSR1	621	1215
GOSR2	1238	2441
KDELR1	-5094	10752
KDELR2	-5893	12387
KDELR3	976	1922
LMAN1	-3431	7220
LMAN2	-6558	13641
LMAN2L	-3429	7218
MAN1A1	-1021	2084
MAN1A2	-6460	13466
MAN1C1	3072	5920
MAN2A1	-1040	2117
MAN2A2	-2336	4840
MANEA	4202	7987
MCFD2	-7065	14425
MGAT1	-6401	13371
MGAT2	-3327	7002
MGAT4A	-5018	10584
MGAT4B	-6279	13132
MGAT4C	1714	3364
MGAT5	-5854	12324
MIA3	-7049	14404
NAPA	-5921	12433
NAPB	-419	853
NAPG	-3872	8187
NSF	-4839	10249
PPP6C	-5241	11074
PPP6R1	-6511	13558
PPP6R3	-623	1271
PREB	1446	2868
RAB1A	-3307	6957
RAB1B	-3479	7340
SAR1B	-2973	6198
SCFD1	485	960
SEC13	-6812	14049
SEC16A	-5971	12546
SEC16B	6744	12908
SEC22A	3312	6374
SEC22B	859	1690
SEC22C	-1684	3433
SEC23A	-2717	5659
SEC23IP	390	767
SEC24A	-6839	14088
SEC24B	-5475	11541
SEC24C	-6236	13047
SEC24D	-7134	14520
SEC31A	-5766	12138
SERPINA1	4014	7622
SPTAN1	2385	4610
SPTBN1	-4901	10356
SPTBN2	3883	7379
ST3GAL4	-6801	14033
ST6GAL1	-1828	3739
STX17	2586	4997
STX5	-5300	11191
TBC1D20	-6203	12985
TFG	-5336	11250
TGFA	-4511	9574
TMED10	-6116	12817
TMED2	-7071	14433
TMED3	-4057	8567
TMED7	-6933	14240
TMED9	-6502	13545
TMEM115	-6764	13976
TRAPPC1	3089	5956
TRAPPC10	-6585	13677
TRAPPC2	3547	6775
TRAPPC2L	-4576	9709
TRAPPC3	-4032	8524
TRAPPC4	1781	3487
TRAPPC5	239	470
TRAPPC6A	7244	14069
TRAPPC6B	2584	4993
TRAPPC9	5033	9528
USO1	-3509	7413
YKT6	-4899	10349

---

---

Calnexin/calreticulin cycle

Calnexin/calreticulin cycle

metric	value
setSize	25
pMANOVA	1.47e-09
p.adjustMANOVA	4.06e-08
s.dist	0.75
s.x	-0.627
s.abs	0.412
p.x	5.76e-08
p.abs	0.000369

Top 20 genes

Gene	x	abs
CALR	-7142	14529
SEL1L	-7124	14508
SYVN1	-7108	14485
EDEM1	-7103	14479
CANX	-7092	14462
PDIA3	-7086	14454
DERL2	-7046	14399
OS9	-6986	14320
UGGT1	-6954	14270
RNF5	-6629	13745
RNF185	-6359	13291
RNF103	-6135	12848
PRKCSH	-5934	12463
EDEM2	-5520	11628
UBA52	-5068	10707
UBB	-4263	9013
MAN1B1	-3561	7534
RNF139	-3064	6382
RPS27A	-2773	5776
AMFR	-2698	5612

Click HERE to show all gene set members

All member genes

	x	abs
AMFR	-2698	5612
CALR	-7142	14529
CANX	-7092	14462
DERL2	-7046	14399
EDEM1	-7103	14479
EDEM2	-5520	11628
EDEM3	-1903	3904
GANAB	2813	5417
MAN1B1	-3561	7534
OS9	-6986	14320
PDIA3	-7086	14454
PRKCSH	-5934	12463
RNF103	-6135	12848
RNF139	-3064	6382
RNF185	-6359	13291
RNF5	-6629	13745
RPS27A	-2773	5776
SEL1L	-7124	14508
SYVN1	-7108	14485
TRIM13	1883	3695
UBA52	-5068	10707
UBB	-4263	9013
UBC	779	1551
UGGT1	-6954	14270
UGGT2	1425	2839

---

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.1.2 (2021-11-01)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 20.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.9.0
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.9.0
## 
## locale:
##  [1] LC_CTYPE=en_AU.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_AU.UTF-8        LC_COLLATE=en_AU.UTF-8    
##  [5] LC_MONETARY=en_AU.UTF-8    LC_MESSAGES=en_AU.UTF-8   
##  [7] LC_PAPER=en_AU.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_AU.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.2.4               GGally_2.1.2               
##  [3] ggplot2_3.3.5               reshape2_1.4.4             
##  [5] beeswarm_0.4.0              gplots_3.1.1               
##  [7] gtools_3.9.2                tibble_3.1.6               
##  [9] dplyr_1.0.7                 echarts4r_0.4.3            
## [11] eulerr_6.1.1                kableExtra_1.3.4           
## [13] mitch_1.4.1                 clusterProfiler_4.0.5      
## [15] DESeq2_1.32.0               SummarizedExperiment_1.22.0
## [17] Biobase_2.52.0              MatrixGenerics_1.4.3       
## [19] matrixStats_0.61.0          GenomicRanges_1.44.0       
## [21] GenomeInfoDb_1.28.4         IRanges_2.26.0             
## [23] S4Vectors_0.30.2            BiocGenerics_0.38.0        
## [25] getDEE2_1.2.0              
## 
## loaded via a namespace (and not attached):
##   [1] shadowtext_0.1.1       fastmatch_1.1-3        systemfonts_1.0.3     
##   [4] plyr_1.8.6             igraph_1.2.11          lazyeval_0.2.2        
##   [7] polylabelr_0.2.0       splines_4.1.2          BiocParallel_1.26.2   
##  [10] digest_0.6.29          yulab.utils_0.0.4      htmltools_0.5.2       
##  [13] GOSemSim_2.18.1        viridis_0.6.2          GO.db_3.13.0          
##  [16] fansi_1.0.0            magrittr_2.0.1         memoise_2.0.1         
##  [19] Biostrings_2.60.2      annotate_1.70.0        graphlayouts_0.8.0    
##  [22] svglite_2.0.0          enrichplot_1.12.3      colorspace_2.0-2      
##  [25] rvest_1.0.2            blob_1.2.2             ggrepel_0.9.1         
##  [28] xfun_0.29              tcltk_4.1.2            crayon_1.4.2          
##  [31] RCurl_1.98-1.5         jsonlite_1.7.2         scatterpie_0.1.7      
##  [34] genefilter_1.74.1      survival_3.2-13        ape_5.6-1             
##  [37] glue_1.6.0             polyclip_1.10-0        gtable_0.3.0          
##  [40] zlibbioc_1.38.0        XVector_0.32.0         webshot_0.5.2         
##  [43] htm2txt_2.1.1          DelayedArray_0.18.0    scales_1.1.1          
##  [46] DOSE_3.18.3            DBI_1.1.2              Rcpp_1.0.7            
##  [49] viridisLite_0.4.0      xtable_1.8-4           gridGraphics_0.5-1    
##  [52] tidytree_0.3.7         bit_4.0.4              htmlwidgets_1.5.4     
##  [55] httr_1.4.2             fgsea_1.18.0           RColorBrewer_1.1-2    
##  [58] ellipsis_0.3.2         pkgconfig_2.0.3        reshape_0.8.8         
##  [61] XML_3.99-0.8           farver_2.1.0           sass_0.4.0            
##  [64] locfit_1.5-9.4         utf8_1.2.2             labeling_0.4.2        
##  [67] ggplotify_0.1.0        tidyselect_1.1.1       rlang_0.4.12          
##  [70] later_1.3.0            AnnotationDbi_1.54.1   munsell_0.5.0         
##  [73] tools_4.1.2            cachem_1.0.6           downloader_0.4        
##  [76] generics_0.1.1         RSQLite_2.2.9          evaluate_0.14         
##  [79] stringr_1.4.0          fastmap_1.1.0          yaml_2.2.1            
##  [82] ggtree_3.0.4           knitr_1.37             bit64_4.0.5           
##  [85] tidygraph_1.2.0        caTools_1.18.2         purrr_0.3.4           
##  [88] KEGGREST_1.32.0        ggraph_2.0.5           nlme_3.1-153          
##  [91] mime_0.12              aplot_0.1.2            xml2_1.3.3            
##  [94] DO.db_2.9              rstudioapi_0.13        compiler_4.1.2        
##  [97] png_0.1-7              testthat_3.1.1         treeio_1.16.2         
## [100] tweenr_1.0.2           geneplotter_1.70.0     bslib_0.3.1           
## [103] stringi_1.7.6          highr_0.9              desc_1.4.0            
## [106] lattice_0.20-45        Matrix_1.4-0           vctrs_0.3.8           
## [109] pillar_1.6.4           lifecycle_1.0.1        jquerylib_0.1.4       
## [112] data.table_1.14.2      cowplot_1.1.1          bitops_1.0-7          
## [115] httpuv_1.6.5           patchwork_1.1.1        qvalue_2.24.0         
## [118] R6_2.5.1               promises_1.2.0.1       KernSmooth_2.23-20    
## [121] gridExtra_2.3          MASS_7.3-54            assertthat_0.2.1      
## [124] rprojroot_2.0.2        withr_2.4.3            GenomeInfoDbData_1.2.6
## [127] grid_4.1.2             ggfun_0.0.4            tidyr_1.1.4           
## [130] rmarkdown_2.11         ggforce_0.3.3          shiny_1.7.1

END of report