Mitch Report
Antony Kaspi & Mark Ziemann
date generated: 2022-01-20
Background
Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch
Input profiles
Here is the first few lines of the input profile.
## x
## A1BG 4.1644895
## A1CF 2.8783151
## A2M 0.3828562
## A4GALT 1.0571952
## AAAS 1.0071471
## AACS -2.0539621| Profile metrics | |
|---|---|
| num_genesets | 2512 |
| num_genes_in_profile | 14533 |
| duplicated_genes_present | 0 |
| num_profile_genes_in_sets | 7596 |
| num_profile_genes_not_in_sets | 6937 |
Here is a plot of the input profiles. Note the dynamic ranges. 
Here is the contour plot of the profile including all detected genes.
Input genesets
Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt| Gene sets metrics | |
|---|---|
| num_genesets | 2512 |
| num_genesets_excluded | 1135 |
| num_genesets_included | 1377 |
Differential pathway expression
Interactive enrichment scatterplot
Significance is calculated by -log10(p-value). All points shown are FDR<0.05.
Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.
Results table
Top N= 50 gene sets| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| Cellular responses to stimuli | 641 | 1.36e-21 | -0.222 | 1.87e-18 |
| Cellular responses to stress | 633 | 2.20e-20 | -0.217 | 1.51e-17 |
| Infectious disease | 637 | 1.06e-18 | -0.206 | 4.88e-16 |
| SRP-dependent cotranslational protein targeting to membrane | 109 | 1.48e-17 | -0.473 | 5.09e-15 |
| Asparagine N-linked glycosylation | 252 | 6.70e-17 | -0.306 | 1.85e-14 |
| Axon guidance | 424 | 2.94e-16 | -0.232 | 6.75e-14 |
| Cellular response to starvation | 149 | 2.02e-14 | -0.363 | 3.98e-12 |
| Metabolism of proteins | 1550 | 3.25e-14 | -0.118 | 5.59e-12 |
| Nervous system development | 444 | 6.25e-14 | -0.209 | 9.56e-12 |
| L13a-mediated translational silencing of Ceruloplasmin expression | 108 | 4.15e-13 | -0.404 | 5.71e-11 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | 109 | 5.93e-13 | -0.399 | 6.44e-11 |
| Developmental Biology | 677 | 6.00e-13 | -0.163 | 6.44e-11 |
| Signal Transduction | 1748 | 6.08e-13 | -0.106 | 6.44e-11 |
| Cholesterol biosynthesis | 24 | 8.63e-13 | 0.843 | 8.49e-11 |
| Translation | 270 | 9.51e-13 | -0.253 | 8.73e-11 |
| Cap-dependent Translation Initiation | 116 | 1.61e-12 | -0.380 | 1.30e-10 |
| Eukaryotic Translation Initiation | 116 | 1.61e-12 | -0.380 | 1.30e-10 |
| Regulation of expression of SLITs and ROBOs | 157 | 2.15e-12 | -0.325 | 1.65e-10 |
| Signaling by ROBO receptors | 193 | 2.58e-12 | -0.293 | 1.87e-10 |
| Diseases of signal transduction by growth factor receptors and second messengers | 361 | 3.78e-12 | -0.214 | 2.60e-10 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | 98 | 7.59e-12 | -0.400 | 4.98e-10 |
| Formation of a pool of free 40S subunits | 98 | 1.12e-11 | -0.397 | 6.94e-10 |
| Metabolism of RNA | 658 | 1.16e-11 | -0.156 | 6.94e-10 |
| Eukaryotic Translation Elongation | 91 | 2.06e-11 | -0.407 | 1.18e-09 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | 91 | 2.32e-11 | -0.406 | 1.27e-09 |
| Disease | 1247 | 2.40e-11 | -0.114 | 1.27e-09 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | 111 | 3.73e-11 | -0.364 | 1.83e-09 |
| Nonsense-Mediated Decay (NMD) | 111 | 3.73e-11 | -0.364 | 1.83e-09 |
| Viral mRNA Translation | 86 | 5.18e-11 | -0.410 | 2.46e-09 |
| Influenza Infection | 151 | 6.29e-11 | -0.309 | 2.89e-09 |
| rRNA processing in the nucleus and cytosol | 184 | 7.82e-11 | -0.278 | 3.47e-09 |
| Peptide chain elongation | 86 | 8.24e-11 | -0.405 | 3.55e-09 |
| Immune System | 1374 | 8.91e-11 | -0.106 | 3.72e-09 |
| SARS-CoV Infections | 144 | 1.05e-10 | -0.312 | 4.26e-09 |
| Unfolded Protein Response (UPR) | 89 | 1.43e-10 | -0.393 | 5.62e-09 |
| Major pathway of rRNA processing in the nucleolus and cytosol | 174 | 1.91e-10 | -0.280 | 7.29e-09 |
| Eukaryotic Translation Termination | 89 | 2.80e-10 | -0.387 | 1.04e-08 |
| Vesicle-mediated transport | 555 | 7.17e-10 | -0.154 | 2.60e-08 |
| Signaling by Receptor Tyrosine Kinases | 405 | 7.81e-10 | -0.179 | 2.76e-08 |
| Membrane Trafficking | 531 | 9.78e-10 | -0.156 | 3.37e-08 |
| Selenocysteine synthesis | 89 | 1.00e-09 | -0.375 | 3.37e-08 |
| IRE1alpha activates chaperones | 50 | 2.24e-09 | -0.489 | 7.35e-08 |
| Transport to the Golgi and subsequent modification | 146 | 2.45e-09 | -0.286 | 7.84e-08 |
| DNA strand elongation | 32 | 3.66e-09 | 0.602 | 1.15e-07 |
| PIP3 activates AKT signaling | 223 | 6.57e-09 | -0.226 | 2.01e-07 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | 34 | 7.03e-09 | -0.574 | 2.11e-07 |
| Innate Immune System | 740 | 9.58e-09 | -0.125 | 2.81e-07 |
| Ribosomal scanning and start codon recognition | 58 | 1.02e-08 | -0.435 | 2.93e-07 |
| ER to Golgi Anterograde Transport | 122 | 1.24e-08 | -0.299 | 3.49e-07 |
| Selenoamino acid metabolism | 104 | 1.30e-08 | -0.323 | 3.57e-07 |
Results (complete table)
Click HERE to show results for all gene sets
| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| Cellular responses to stimuli | 641 | 1.36e-21 | -0.222000 | 1.87e-18 |
| Cellular responses to stress | 633 | 2.20e-20 | -0.217000 | 1.51e-17 |
| Infectious disease | 637 | 1.06e-18 | -0.206000 | 4.88e-16 |
| SRP-dependent cotranslational protein targeting to membrane | 109 | 1.48e-17 | -0.473000 | 5.09e-15 |
| Asparagine N-linked glycosylation | 252 | 6.70e-17 | -0.306000 | 1.85e-14 |
| Axon guidance | 424 | 2.94e-16 | -0.232000 | 6.75e-14 |
| Cellular response to starvation | 149 | 2.02e-14 | -0.363000 | 3.98e-12 |
| Metabolism of proteins | 1550 | 3.25e-14 | -0.118000 | 5.59e-12 |
| Nervous system development | 444 | 6.25e-14 | -0.209000 | 9.56e-12 |
| L13a-mediated translational silencing of Ceruloplasmin expression | 108 | 4.15e-13 | -0.404000 | 5.71e-11 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | 109 | 5.93e-13 | -0.399000 | 6.44e-11 |
| Developmental Biology | 677 | 6.00e-13 | -0.163000 | 6.44e-11 |
| Signal Transduction | 1748 | 6.08e-13 | -0.106000 | 6.44e-11 |
| Cholesterol biosynthesis | 24 | 8.63e-13 | 0.843000 | 8.49e-11 |
| Translation | 270 | 9.51e-13 | -0.253000 | 8.73e-11 |
| Cap-dependent Translation Initiation | 116 | 1.61e-12 | -0.380000 | 1.30e-10 |
| Eukaryotic Translation Initiation | 116 | 1.61e-12 | -0.380000 | 1.30e-10 |
| Regulation of expression of SLITs and ROBOs | 157 | 2.15e-12 | -0.325000 | 1.65e-10 |
| Signaling by ROBO receptors | 193 | 2.58e-12 | -0.293000 | 1.87e-10 |
| Diseases of signal transduction by growth factor receptors and second messengers | 361 | 3.78e-12 | -0.214000 | 2.60e-10 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | 98 | 7.59e-12 | -0.400000 | 4.98e-10 |
| Formation of a pool of free 40S subunits | 98 | 1.12e-11 | -0.397000 | 6.94e-10 |
| Metabolism of RNA | 658 | 1.16e-11 | -0.156000 | 6.94e-10 |
| Eukaryotic Translation Elongation | 91 | 2.06e-11 | -0.407000 | 1.18e-09 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | 91 | 2.32e-11 | -0.406000 | 1.27e-09 |
| Disease | 1247 | 2.40e-11 | -0.114000 | 1.27e-09 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | 111 | 3.73e-11 | -0.364000 | 1.83e-09 |
| Nonsense-Mediated Decay (NMD) | 111 | 3.73e-11 | -0.364000 | 1.83e-09 |
| Viral mRNA Translation | 86 | 5.18e-11 | -0.410000 | 2.46e-09 |
| Influenza Infection | 151 | 6.29e-11 | -0.309000 | 2.89e-09 |
| rRNA processing in the nucleus and cytosol | 184 | 7.82e-11 | -0.278000 | 3.47e-09 |
| Peptide chain elongation | 86 | 8.24e-11 | -0.405000 | 3.55e-09 |
| Immune System | 1374 | 8.91e-11 | -0.106000 | 3.72e-09 |
| SARS-CoV Infections | 144 | 1.05e-10 | -0.312000 | 4.26e-09 |
| Unfolded Protein Response (UPR) | 89 | 1.43e-10 | -0.393000 | 5.62e-09 |
| Major pathway of rRNA processing in the nucleolus and cytosol | 174 | 1.91e-10 | -0.280000 | 7.29e-09 |
| Eukaryotic Translation Termination | 89 | 2.80e-10 | -0.387000 | 1.04e-08 |
| Vesicle-mediated transport | 555 | 7.17e-10 | -0.154000 | 2.60e-08 |
| Signaling by Receptor Tyrosine Kinases | 405 | 7.81e-10 | -0.179000 | 2.76e-08 |
| Membrane Trafficking | 531 | 9.78e-10 | -0.156000 | 3.37e-08 |
| Selenocysteine synthesis | 89 | 1.00e-09 | -0.375000 | 3.37e-08 |
| IRE1alpha activates chaperones | 50 | 2.24e-09 | -0.489000 | 7.35e-08 |
| Transport to the Golgi and subsequent modification | 146 | 2.45e-09 | -0.286000 | 7.84e-08 |
| DNA strand elongation | 32 | 3.66e-09 | 0.602000 | 1.15e-07 |
| PIP3 activates AKT signaling | 223 | 6.57e-09 | -0.226000 | 2.01e-07 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | 34 | 7.03e-09 | -0.574000 | 2.11e-07 |
| Innate Immune System | 740 | 9.58e-09 | -0.125000 | 2.81e-07 |
| Ribosomal scanning and start codon recognition | 58 | 1.02e-08 | -0.435000 | 2.93e-07 |
| ER to Golgi Anterograde Transport | 122 | 1.24e-08 | -0.299000 | 3.49e-07 |
| Selenoamino acid metabolism | 104 | 1.30e-08 | -0.323000 | 3.57e-07 |
| Translation initiation complex formation | 58 | 1.63e-08 | -0.429000 | 4.39e-07 |
| XBP1(S) activates chaperone genes | 48 | 2.02e-08 | -0.468000 | 5.36e-07 |
| Diseases of DNA repair | 34 | 3.47e-08 | 0.547000 | 9.02e-07 |
| Influenza Viral RNA Transcription and Replication | 132 | 4.62e-08 | -0.276000 | 1.18e-06 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | 59 | 4.97e-08 | -0.410000 | 1.24e-06 |
| Calnexin/calreticulin cycle | 25 | 5.76e-08 | -0.627000 | 1.41e-06 |
| Post-translational protein modification | 1138 | 5.82e-08 | -0.096700 | 1.41e-06 |
| rRNA processing | 205 | 7.31e-08 | -0.219000 | 1.74e-06 |
| Intracellular signaling by second messengers | 252 | 7.50e-08 | -0.197000 | 1.75e-06 |
| Homologous DNA Pairing and Strand Exchange | 42 | 8.69e-08 | 0.477000 | 1.99e-06 |
| Formation of the ternary complex, and subsequently, the 43S complex | 51 | 8.98e-08 | -0.433000 | 2.03e-06 |
| Signaling by Interleukins | 315 | 9.78e-08 | -0.175000 | 2.17e-06 |
| Signaling by NTRK1 (TRKA) | 102 | 1.00e-07 | -0.305000 | 2.19e-06 |
| Mitotic Prometaphase | 181 | 1.19e-07 | 0.229000 | 2.56e-06 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | 32 | 1.27e-07 | 0.540000 | 2.69e-06 |
| Biological oxidations | 155 | 1.42e-07 | 0.245000 | 2.95e-06 |
| Regulation of Complement cascade | 30 | 1.43e-07 | 0.555000 | 2.95e-06 |
| SARS-CoV-2 Infection | 69 | 2.16e-07 | -0.361000 | 4.38e-06 |
| Autophagy | 121 | 2.79e-07 | -0.271000 | 5.57e-06 |
| Signaling by the B Cell Receptor (BCR) | 96 | 2.97e-07 | -0.303000 | 5.83e-06 |
| Complement cascade | 35 | 3.48e-07 | 0.498000 | 6.75e-06 |
| Cell Cycle | 594 | 3.79e-07 | 0.123000 | 7.25e-06 |
| MAPK family signaling cascades | 244 | 3.99e-07 | -0.189000 | 7.52e-06 |
| Transport of small molecules | 535 | 4.55e-07 | -0.128000 | 8.48e-06 |
| TCR signaling | 91 | 4.87e-07 | -0.305000 | 8.93e-06 |
| Resolution of D-Loop Structures | 33 | 4.98e-07 | 0.506000 | 9.02e-06 |
| Homology Directed Repair | 101 | 5.14e-07 | 0.289000 | 9.20e-06 |
| RHO GTPase cycle | 387 | 8.32e-07 | -0.147000 | 1.47e-05 |
| Fc epsilon receptor (FCERI) signaling | 113 | 8.53e-07 | -0.268000 | 1.49e-05 |
| Defective HDR through Homologous Recombination (HRR) due to BRCA1 loss-of-function | 24 | 1.16e-06 | 0.573000 | 1.89e-05 |
| Defective HDR through Homologous Recombination (HRR) due to PALB2 loss of function | 24 | 1.16e-06 | 0.573000 | 1.89e-05 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | 24 | 1.16e-06 | 0.573000 | 1.89e-05 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | 24 | 1.16e-06 | 0.573000 | 1.89e-05 |
| Diseases of DNA Double-Strand Break Repair | 24 | 1.16e-06 | 0.573000 | 1.89e-05 |
| Presynaptic phase of homologous DNA pairing and strand exchange | 39 | 1.19e-06 | 0.449000 | 1.92e-05 |
| Macroautophagy | 108 | 1.20e-06 | -0.271000 | 1.92e-05 |
| HDR through Homologous Recombination (HRR) | 66 | 1.28e-06 | 0.345000 | 2.02e-05 |
| RAF/MAP kinase cascade | 207 | 1.35e-06 | -0.195000 | 2.11e-05 |
| Chromosome Maintenance | 90 | 1.39e-06 | 0.295000 | 2.12e-05 |
| MyD88 cascade initiated on plasma membrane | 77 | 1.41e-06 | -0.318000 | 2.12e-05 |
| Toll Like Receptor 10 (TLR10) Cascade | 77 | 1.41e-06 | -0.318000 | 2.12e-05 |
| Toll Like Receptor 5 (TLR5) Cascade | 77 | 1.41e-06 | -0.318000 | 2.12e-05 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | 26 | 1.60e-06 | 0.544000 | 2.37e-05 |
| Downstream signaling events of B Cell Receptor (BCR) | 74 | 1.63e-06 | -0.323000 | 2.39e-05 |
| COPI-mediated anterograde transport | 74 | 1.83e-06 | -0.321000 | 2.65e-05 |
| Signaling by WNT | 213 | 1.90e-06 | -0.190000 | 2.71e-05 |
| Toll Like Receptor 3 (TLR3) Cascade | 85 | 1.91e-06 | -0.299000 | 2.71e-05 |
| Cytokine Signaling in Immune system | 492 | 2.02e-06 | -0.126000 | 2.84e-05 |
| ER Quality Control Compartment (ERQC) | 20 | 2.26e-06 | -0.611000 | 3.12e-05 |
| Hh mutants are degraded by ERAD | 53 | 2.27e-06 | -0.376000 | 3.12e-05 |
| Signaling by NTRKs | 115 | 2.52e-06 | -0.254000 | 3.44e-05 |
| MyD88 dependent cascade initiated on endosome | 81 | 2.86e-06 | -0.301000 | 3.79e-05 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | 81 | 2.86e-06 | -0.301000 | 3.79e-05 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | 81 | 2.86e-06 | -0.301000 | 3.79e-05 |
| Hh mutants abrogate ligand secretion | 55 | 3.23e-06 | -0.363000 | 4.24e-05 |
| Hedgehog ligand biogenesis | 59 | 3.35e-06 | -0.350000 | 4.35e-05 |
| MAPK1/MAPK3 signaling | 212 | 3.38e-06 | -0.186000 | 4.35e-05 |
| Signaling by Insulin receptor | 59 | 3.60e-06 | -0.349000 | 4.60e-05 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | 95 | 3.73e-06 | 0.275000 | 4.67e-05 |
| Toll Like Receptor 9 (TLR9) Cascade | 85 | 3.75e-06 | -0.290000 | 4.67e-05 |
| Defective CFTR causes cystic fibrosis | 56 | 3.77e-06 | -0.357000 | 4.67e-05 |
| Unwinding of DNA | 12 | 4.06e-06 | 0.768000 | 4.99e-05 |
| MyD88-independent TLR4 cascade | 88 | 4.92e-06 | -0.282000 | 5.94e-05 |
| TRIF(TICAM1)-mediated TLR4 signaling | 88 | 4.92e-06 | -0.282000 | 5.94e-05 |
| Downstream TCR signaling | 76 | 4.96e-06 | -0.303000 | 5.94e-05 |
| Fatty acid metabolism | 130 | 6.13e-06 | 0.230000 | 7.27e-05 |
| Activation of ATR in response to replication stress | 37 | 7.05e-06 | 0.427000 | 8.29e-05 |
| Phase II - Conjugation of compounds | 75 | 7.40e-06 | 0.299000 | 8.64e-05 |
| Chromatin modifying enzymes | 195 | 8.16e-06 | -0.186000 | 9.37e-05 |
| Chromatin organization | 195 | 8.16e-06 | -0.186000 | 9.37e-05 |
| Degradation of beta-catenin by the destruction complex | 80 | 8.54e-06 | -0.288000 | 9.72e-05 |
| DNA Double-Strand Break Repair | 127 | 9.98e-06 | 0.227000 | 1.13e-04 |
| Cell Cycle, Mitotic | 478 | 1.02e-05 | 0.118000 | 1.15e-04 |
| MAP kinase activation | 61 | 1.03e-05 | -0.327000 | 1.15e-04 |
| Activation of NF-kappaB in B cells | 62 | 1.07e-05 | -0.323000 | 1.18e-04 |
| PTEN Regulation | 134 | 1.09e-05 | -0.220000 | 1.19e-04 |
| Regulation of HMOX1 expression and activity | 62 | 1.18e-05 | -0.322000 | 1.28e-04 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | 19 | 1.22e-05 | -0.580000 | 1.31e-04 |
| Adaptive Immune System | 551 | 1.25e-05 | -0.110000 | 1.34e-04 |
| Insulin receptor recycling | 23 | 1.37e-05 | -0.524000 | 1.45e-04 |
| Interleukin-17 signaling | 65 | 1.41e-05 | -0.312000 | 1.49e-04 |
| Cilium Assembly | 172 | 1.43e-05 | 0.192000 | 1.49e-04 |
| Deposition of new CENPA-containing nucleosomes at the centromere | 27 | 1.69e-05 | 0.478000 | 1.74e-04 |
| Nucleosome assembly | 27 | 1.69e-05 | 0.478000 | 1.74e-04 |
| RAC3 GTPase cycle | 79 | 1.72e-05 | -0.280000 | 1.76e-04 |
| trans-Golgi Network Vesicle Budding | 68 | 1.85e-05 | -0.300000 | 1.88e-04 |
| Interleukin-1 signaling | 92 | 2.33e-05 | -0.255000 | 2.34e-04 |
| Deubiquitination | 218 | 2.36e-05 | -0.167000 | 2.35e-04 |
| DNA Repair | 276 | 2.51e-05 | 0.148000 | 2.49e-04 |
| HDR through Single Strand Annealing (SSA) | 37 | 2.53e-05 | 0.400000 | 2.49e-04 |
| UCH proteinases | 81 | 2.63e-05 | -0.270000 | 2.57e-04 |
| COPII-mediated vesicle transport | 63 | 2.73e-05 | -0.306000 | 2.65e-04 |
| Cytoprotection by HMOX1 | 118 | 2.94e-05 | -0.223000 | 2.83e-04 |
| Regulation of RUNX2 expression and activity | 62 | 3.63e-05 | -0.303000 | 3.48e-04 |
| RAC2 GTPase cycle | 75 | 3.85e-05 | -0.275000 | 3.66e-04 |
| Signaling by NOTCH | 156 | 3.98e-05 | -0.191000 | 3.75e-04 |
| ROS sensing by NFE2L2 | 54 | 4.25e-05 | -0.322000 | 3.98e-04 |
| Telomere C-strand (Lagging Strand) Synthesis | 34 | 4.74e-05 | 0.403000 | 4.41e-04 |
| FCERI mediated NF-kB activation | 70 | 5.17e-05 | -0.280000 | 4.78e-04 |
| Degradation of AXIN | 52 | 5.39e-05 | -0.324000 | 4.95e-04 |
| Circadian Clock | 65 | 5.64e-05 | -0.289000 | 5.14e-04 |
| Potential therapeutics for SARS | 77 | 5.98e-05 | -0.265000 | 5.42e-04 |
| ABC transporter disorders | 70 | 6.06e-05 | -0.277000 | 5.45e-04 |
| ABC-family proteins mediated transport | 92 | 6.17e-05 | -0.242000 | 5.51e-04 |
| Cell Cycle Checkpoints | 249 | 6.20e-05 | 0.148000 | 5.51e-04 |
| Regulation of PTEN stability and activity | 64 | 6.54e-05 | -0.289000 | 5.77e-04 |
| C-type lectin receptors (CLRs) | 113 | 6.70e-05 | -0.217000 | 5.88e-04 |
| Nuclear Events (kinase and transcription factor activation) | 56 | 7.25e-05 | -0.307000 | 6.32e-04 |
| TCF dependent signaling in response to WNT | 145 | 7.77e-05 | -0.190000 | 6.73e-04 |
| Negative regulation of MAPK pathway | 41 | 7.97e-05 | -0.356000 | 6.86e-04 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | 86 | 8.18e-05 | -0.246000 | 6.93e-04 |
| Transferrin endocytosis and recycling | 29 | 8.19e-05 | -0.423000 | 6.93e-04 |
| MyD88 deficiency (TLR2/4) | 11 | 8.20e-05 | 0.686000 | 6.93e-04 |
| Cellular response to chemical stress | 145 | 9.16e-05 | -0.188000 | 7.69e-04 |
| Interleukin-1 family signaling | 111 | 9.25e-05 | -0.215000 | 7.72e-04 |
| mRNA Splicing - Major Pathway | 178 | 9.49e-05 | -0.170000 | 7.86e-04 |
| Cargo concentration in the ER | 27 | 9.54e-05 | -0.434000 | 7.86e-04 |
| Lagging Strand Synthesis | 20 | 1.02e-04 | 0.502000 | 8.37e-04 |
| CLEC7A (Dectin-1) signaling | 92 | 1.03e-04 | -0.234000 | 8.37e-04 |
| Mitotic Spindle Checkpoint | 107 | 1.03e-04 | 0.217000 | 8.37e-04 |
| IRAK4 deficiency (TLR2/4) | 12 | 1.08e-04 | 0.646000 | 8.69e-04 |
| Signaling by VEGF | 89 | 1.11e-04 | -0.237000 | 8.85e-04 |
| Dectin-1 mediated noncanonical NF-kB signaling | 58 | 1.19e-04 | -0.292000 | 9.46e-04 |
| NIK–>noncanonical NF-kB signaling | 56 | 1.21e-04 | -0.297000 | 9.59e-04 |
| Regulation of RUNX3 expression and activity | 54 | 1.22e-04 | -0.302000 | 9.59e-04 |
| Activation of the pre-replicative complex | 32 | 1.24e-04 | 0.392000 | 9.73e-04 |
| TGF-beta receptor signaling activates SMADs | 31 | 1.27e-04 | -0.398000 | 9.85e-04 |
| RAC1 GTPase cycle | 149 | 1.36e-04 | -0.181000 | 1.05e-03 |
| mRNA Splicing | 186 | 1.41e-04 | -0.162000 | 1.09e-03 |
| Activation of gene expression by SREBF (SREBP) | 42 | 1.71e-04 | 0.335000 | 1.31e-03 |
| Base Excision Repair | 45 | 1.74e-04 | 0.324000 | 1.32e-03 |
| MAPK6/MAPK4 signaling | 79 | 1.78e-04 | -0.244000 | 1.35e-03 |
| Ubiquitin-dependent degradation of Cyclin D | 49 | 1.88e-04 | -0.308000 | 1.42e-03 |
| RHOG GTPase cycle | 66 | 1.96e-04 | -0.265000 | 1.47e-03 |
| Degradation of GLI1 by the proteasome | 55 | 2.04e-04 | -0.290000 | 1.52e-03 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | 52 | 2.07e-04 | -0.298000 | 1.53e-03 |
| Processive synthesis on the lagging strand | 15 | 2.13e-04 | 0.552000 | 1.57e-03 |
| Anchoring of the basal body to the plasma membrane | 93 | 2.23e-04 | 0.222000 | 1.63e-03 |
| Degradation of GLI2 by the proteasome | 55 | 2.28e-04 | -0.287000 | 1.65e-03 |
| GLI3 is processed to GLI3R by the proteasome | 55 | 2.28e-04 | -0.287000 | 1.65e-03 |
| Iron uptake and transport | 55 | 2.28e-04 | -0.287000 | 1.65e-03 |
| Transcriptional regulation by RUNX3 | 91 | 2.37e-04 | -0.223000 | 1.70e-03 |
| Transport of inorganic cations/anions and amino acids/oligopeptides | 71 | 2.40e-04 | -0.252000 | 1.71e-03 |
| Lysosome Vesicle Biogenesis | 31 | 2.40e-04 | -0.381000 | 1.71e-03 |
| AURKA Activation by TPX2 | 69 | 2.42e-04 | 0.256000 | 1.71e-03 |
| Neutrophil degranulation | 352 | 2.53e-04 | -0.114000 | 1.77e-03 |
| Degradation of DVL | 53 | 2.57e-04 | -0.290000 | 1.80e-03 |
| Initial triggering of complement | 12 | 2.72e-04 | 0.607000 | 1.89e-03 |
| Glutathione conjugation | 29 | 2.74e-04 | 0.390000 | 1.90e-03 |
| Extension of Telomeres | 50 | 2.83e-04 | 0.297000 | 1.95e-03 |
| Heme signaling | 42 | 2.87e-04 | -0.323000 | 1.97e-03 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | 170 | 2.96e-04 | -0.161000 | 2.00e-03 |
| PCP/CE pathway | 79 | 2.96e-04 | -0.236000 | 2.00e-03 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | 47 | 2.97e-04 | -0.305000 | 2.00e-03 |
| Resolution of Sister Chromatid Cohesion | 103 | 3.00e-04 | 0.206000 | 2.02e-03 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | 51 | 3.02e-04 | -0.293000 | 2.02e-03 |
| Regulation of TLR by endogenous ligand | 12 | 3.09e-04 | 0.601000 | 2.06e-03 |
| Signaling by TGF-beta Receptor Complex | 73 | 3.19e-04 | -0.244000 | 2.11e-03 |
| Golgi Associated Vesicle Biogenesis | 55 | 3.31e-04 | -0.280000 | 2.18e-03 |
| Ub-specific processing proteases | 150 | 3.35e-04 | -0.170000 | 2.19e-03 |
| Amino acids regulate mTORC1 | 51 | 3.84e-04 | -0.288000 | 2.51e-03 |
| Processing of Capped Intron-Containing Pre-mRNA | 236 | 3.92e-04 | -0.134000 | 2.55e-03 |
| PI3K/AKT Signaling in Cancer | 68 | 4.22e-04 | -0.247000 | 2.71e-03 |
| Leading Strand Synthesis | 14 | 4.25e-04 | 0.544000 | 2.71e-03 |
| Polymerase switching | 14 | 4.25e-04 | 0.544000 | 2.71e-03 |
| EML4 and NUDC in mitotic spindle formation | 94 | 4.25e-04 | 0.210000 | 2.71e-03 |
| ROS and RNS production in phagocytes | 27 | 4.38e-04 | -0.391000 | 2.78e-03 |
| Collagen chain trimerization | 18 | 4.42e-04 | 0.478000 | 2.79e-03 |
| Signalling to ERKs | 31 | 4.50e-04 | -0.364000 | 2.83e-03 |
| Formation of Fibrin Clot (Clotting Cascade) | 28 | 4.53e-04 | 0.383000 | 2.83e-03 |
| Toll-like Receptor Cascades | 126 | 4.59e-04 | -0.181000 | 2.86e-03 |
| Signaling by EGFR | 44 | 4.63e-04 | -0.305000 | 2.87e-03 |
| Transcriptional regulation by RUNX2 | 96 | 4.96e-04 | -0.206000 | 3.06e-03 |
| Cellular response to hypoxia | 72 | 5.07e-04 | -0.237000 | 3.12e-03 |
| Autodegradation of the E3 ubiquitin ligase COP1 | 49 | 5.22e-04 | -0.287000 | 3.18e-03 |
| Negative regulation of NOTCH4 signaling | 52 | 5.25e-04 | -0.278000 | 3.18e-03 |
| Amino acid transport across the plasma membrane | 28 | 5.25e-04 | -0.379000 | 3.18e-03 |
| VEGFA-VEGFR2 Pathway | 83 | 5.69e-04 | -0.219000 | 3.43e-03 |
| Removal of the Flap Intermediate | 14 | 5.71e-04 | 0.532000 | 3.43e-03 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | 63 | 5.75e-04 | -0.251000 | 3.44e-03 |
| Transcriptional regulation by RUNX1 | 147 | 5.80e-04 | -0.165000 | 3.46e-03 |
| Recruitment of NuMA to mitotic centrosomes | 77 | 5.95e-04 | 0.227000 | 3.53e-03 |
| Uptake and actions of bacterial toxins | 22 | 6.22e-04 | -0.421000 | 3.68e-03 |
| Polymerase switching on the C-strand of the telomere | 26 | 6.31e-04 | 0.387000 | 3.71e-03 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | 61 | 6.38e-04 | -0.253000 | 3.74e-03 |
| Regulation of RAS by GAPs | 62 | 6.62e-04 | -0.250000 | 3.83e-03 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | 90 | 6.63e-04 | 0.208000 | 3.83e-03 |
| Amplification of signal from the kinetochores | 90 | 6.63e-04 | 0.208000 | 3.83e-03 |
| Resolution of Abasic Sites (AP sites) | 37 | 6.97e-04 | 0.322000 | 3.98e-03 |
| Loss of Nlp from mitotic centrosomes | 66 | 6.97e-04 | 0.241000 | 3.98e-03 |
| Loss of proteins required for interphase microtubule organization from the centrosome | 66 | 6.97e-04 | 0.241000 | 3.98e-03 |
| Signaling by NOTCH4 | 75 | 7.22e-04 | -0.226000 | 4.11e-03 |
| Regulation of TP53 Activity through Acetylation | 29 | 7.88e-04 | -0.360000 | 4.45e-03 |
| PI Metabolism | 71 | 7.89e-04 | -0.231000 | 4.45e-03 |
| Downregulation of TGF-beta receptor signaling | 25 | 8.23e-04 | -0.387000 | 4.62e-03 |
| Vif-mediated degradation of APOBEC3G | 51 | 8.63e-04 | -0.270000 | 4.83e-03 |
| Regulation of ornithine decarboxylase (ODC) | 48 | 8.92e-04 | -0.277000 | 4.97e-03 |
| SCF-beta-TrCP mediated degradation of Emi1 | 52 | 9.06e-04 | -0.266000 | 5.03e-03 |
| Clathrin-mediated endocytosis | 116 | 9.37e-04 | -0.178000 | 5.18e-03 |
| Class I MHC mediated antigen processing & presentation | 331 | 9.63e-04 | -0.106000 | 5.31e-03 |
| Meiotic recombination | 22 | 9.76e-04 | 0.406000 | 5.34e-03 |
| Hedgehog ‘on’ state | 75 | 9.78e-04 | -0.220000 | 5.34e-03 |
| Centrosome maturation | 78 | 9.92e-04 | 0.216000 | 5.38e-03 |
| Recruitment of mitotic centrosome proteins and complexes | 78 | 9.92e-04 | 0.216000 | 5.38e-03 |
| Fanconi Anemia Pathway | 36 | 1.01e-03 | 0.317000 | 5.47e-03 |
| AKT phosphorylates targets in the cytosol | 13 | 1.07e-03 | -0.524000 | 5.75e-03 |
| Regulation of Apoptosis | 50 | 1.09e-03 | -0.267000 | 5.82e-03 |
| Beta-catenin independent WNT signaling | 117 | 1.09e-03 | -0.175000 | 5.82e-03 |
| HDMs demethylate histones | 21 | 1.12e-03 | -0.411000 | 5.93e-03 |
| Signaling by Rho GTPases, Miro GTPases and RHOBTB3 | 566 | 1.13e-03 | -0.080600 | 5.98e-03 |
| Host Interactions of HIV factors | 122 | 1.17e-03 | -0.170000 | 6.16e-03 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | 88 | 1.19e-03 | -0.200000 | 6.17e-03 |
| Toll Like Receptor 2 (TLR2) Cascade | 88 | 1.19e-03 | -0.200000 | 6.17e-03 |
| Toll Like Receptor TLR1:TLR2 Cascade | 88 | 1.19e-03 | -0.200000 | 6.17e-03 |
| Toll Like Receptor TLR6:TLR2 Cascade | 88 | 1.19e-03 | -0.200000 | 6.17e-03 |
| Telomere Maintenance | 65 | 1.35e-03 | 0.230000 | 6.98e-03 |
| Cross-presentation of soluble exogenous antigens (endosomes) | 42 | 1.35e-03 | -0.286000 | 6.98e-03 |
| G2/M DNA damage checkpoint | 60 | 1.41e-03 | 0.239000 | 7.22e-03 |
| RHOV GTPase cycle | 35 | 1.47e-03 | -0.311000 | 7.53e-03 |
| Regulation of actin dynamics for phagocytic cup formation | 49 | 1.53e-03 | -0.262000 | 7.79e-03 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | 16 | 1.55e-03 | -0.457000 | 7.88e-03 |
| Vpu mediated degradation of CD4 | 49 | 1.65e-03 | -0.260000 | 8.36e-03 |
| Negative regulation of the PI3K/AKT network | 74 | 1.68e-03 | -0.211000 | 8.48e-03 |
| MAPK targets/ Nuclear events mediated by MAP kinases | 30 | 1.69e-03 | -0.331000 | 8.49e-03 |
| Infection with Mycobacterium tuberculosis | 22 | 1.71e-03 | -0.386000 | 8.54e-03 |
| TBC/RABGAPs | 43 | 1.74e-03 | -0.276000 | 8.70e-03 |
| HIV Infection | 217 | 1.79e-03 | -0.123000 | 8.87e-03 |
| Toll Like Receptor 4 (TLR4) Cascade | 110 | 1.80e-03 | -0.172000 | 8.92e-03 |
| Fcgamma receptor (FCGR) dependent phagocytosis | 70 | 1.82e-03 | -0.216000 | 8.99e-03 |
| EPH-Ephrin signaling | 80 | 1.87e-03 | -0.201000 | 9.21e-03 |
| Signaling by EGFR in Cancer | 22 | 1.96e-03 | -0.381000 | 9.60e-03 |
| Nuclear Receptor transcription pathway | 41 | 1.97e-03 | -0.279000 | 9.60e-03 |
| Intraflagellar transport | 34 | 2.00e-03 | 0.306000 | 9.71e-03 |
| Signaling by NOTCH1 | 62 | 2.00e-03 | -0.227000 | 9.71e-03 |
| RHOQ GTPase cycle | 54 | 2.03e-03 | -0.243000 | 9.83e-03 |
| Response of Mtb to phagocytosis | 21 | 2.12e-03 | -0.387000 | 1.02e-02 |
| Base-Excision Repair, AP Site Formation | 18 | 2.12e-03 | 0.418000 | 1.02e-02 |
| Retrograde transport at the Trans-Golgi-Network | 48 | 2.25e-03 | -0.255000 | 1.08e-02 |
| RHOBTB GTPase Cycle | 33 | 2.26e-03 | -0.307000 | 1.08e-02 |
| TNFR2 non-canonical NF-kB pathway | 77 | 2.26e-03 | -0.201000 | 1.08e-02 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | 14 | 2.34e-03 | 0.470000 | 1.11e-02 |
| rRNA modification in the nucleus and cytosol | 58 | 2.47e-03 | -0.230000 | 1.17e-02 |
| ESR-mediated signaling | 138 | 2.49e-03 | -0.149000 | 1.17e-02 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | 57 | 2.56e-03 | -0.231000 | 1.20e-02 |
| SARS-CoV-1 Infection | 48 | 2.57e-03 | -0.252000 | 1.20e-02 |
| Disorders of transmembrane transporters | 140 | 2.57e-03 | -0.148000 | 1.20e-02 |
| Folding of actin by CCT/TriC | 10 | 2.64e-03 | -0.549000 | 1.22e-02 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | 14 | 2.72e-03 | 0.463000 | 1.26e-02 |
| Stabilization of p53 | 54 | 2.74e-03 | -0.236000 | 1.26e-02 |
| Cell-extracellular matrix interactions | 14 | 2.88e-03 | -0.460000 | 1.32e-02 |
| Uptake and function of anthrax toxins | 11 | 2.92e-03 | -0.518000 | 1.33e-02 |
| NGF-stimulated transcription | 35 | 2.92e-03 | -0.291000 | 1.33e-02 |
| Response of EIF2AK1 (HRI) to heme deficiency | 15 | 2.96e-03 | -0.443000 | 1.35e-02 |
| Metabolism of polyamines | 56 | 3.00e-03 | -0.229000 | 1.36e-02 |
| Signaling by FGFR4 | 31 | 3.05e-03 | -0.307000 | 1.38e-02 |
| EGFR downregulation | 26 | 3.06e-03 | -0.336000 | 1.38e-02 |
| Ion channel transport | 116 | 3.09e-03 | -0.159000 | 1.39e-02 |
| Extra-nuclear estrogen signaling | 57 | 3.21e-03 | -0.226000 | 1.43e-02 |
| Signaling by Rho GTPases | 551 | 3.22e-03 | -0.073900 | 1.43e-02 |
| Peroxisomal protein import | 57 | 3.37e-03 | 0.225000 | 1.50e-02 |
| Cleavage of the damaged pyrimidine | 16 | 3.50e-03 | 0.422000 | 1.54e-02 |
| Depyrimidination | 16 | 3.50e-03 | 0.422000 | 1.54e-02 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | 16 | 3.50e-03 | 0.422000 | 1.54e-02 |
| Mismatch Repair | 15 | 3.54e-03 | 0.435000 | 1.55e-02 |
| Cargo recognition for clathrin-mediated endocytosis | 81 | 3.58e-03 | -0.187000 | 1.56e-02 |
| TP53 Regulates Metabolic Genes | 84 | 3.78e-03 | -0.183000 | 1.64e-02 |
| Signaling by TGFB family members | 87 | 3.78e-03 | -0.180000 | 1.64e-02 |
| Apoptosis | 153 | 3.86e-03 | -0.136000 | 1.67e-02 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | 22 | 3.93e-03 | -0.355000 | 1.70e-02 |
| Interleukin-12 signaling | 38 | 4.14e-03 | -0.269000 | 1.78e-02 |
| Signaling by Hedgehog | 116 | 4.17e-03 | -0.154000 | 1.79e-02 |
| Negative regulation of FGFR1 signaling | 22 | 4.24e-03 | -0.352000 | 1.81e-02 |
| Phase I - Functionalization of compounds | 74 | 4.26e-03 | 0.192000 | 1.81e-02 |
| Processive synthesis on the C-strand of the telomere | 19 | 4.50e-03 | 0.377000 | 1.91e-02 |
| Processing of DNA double-strand break ends | 62 | 4.76e-03 | 0.207000 | 2.02e-02 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | 18 | 4.86e-03 | -0.383000 | 2.04e-02 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | 18 | 4.86e-03 | -0.383000 | 2.04e-02 |
| CDT1 association with the CDC6:ORC:origin complex | 56 | 4.88e-03 | -0.218000 | 2.04e-02 |
| Signaling by FGFR3 | 32 | 4.89e-03 | -0.288000 | 2.04e-02 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | 31 | 4.90e-03 | -0.292000 | 2.04e-02 |
| RND2 GTPase cycle | 37 | 5.03e-03 | -0.267000 | 2.09e-02 |
| Organelle biogenesis and maintenance | 243 | 5.10e-03 | 0.105000 | 2.12e-02 |
| Negative regulation of FGFR4 signaling | 21 | 5.12e-03 | -0.353000 | 2.12e-02 |
| Post-translational modification: synthesis of GPI-anchored proteins | 48 | 5.19e-03 | 0.233000 | 2.13e-02 |
| Antigen processing-Cross presentation | 87 | 5.21e-03 | -0.173000 | 2.13e-02 |
| Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | 49 | 5.23e-03 | -0.231000 | 2.13e-02 |
| p53-Independent DNA Damage Response | 49 | 5.23e-03 | -0.231000 | 2.13e-02 |
| p53-Independent G1/S DNA damage checkpoint | 49 | 5.23e-03 | -0.231000 | 2.13e-02 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | 68 | 5.41e-03 | -0.195000 | 2.20e-02 |
| p53-Dependent G1 DNA Damage Response | 62 | 5.64e-03 | -0.203000 | 2.27e-02 |
| p53-Dependent G1/S DNA damage checkpoint | 62 | 5.64e-03 | -0.203000 | 2.27e-02 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | 21 | 5.65e-03 | 0.349000 | 2.27e-02 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | 21 | 5.65e-03 | 0.349000 | 2.27e-02 |
| Cytosolic sensors of pathogen-associated DNA | 53 | 5.67e-03 | -0.220000 | 2.27e-02 |
| Regulation of signaling by CBL | 14 | 6.41e-03 | -0.421000 | 2.56e-02 |
| Scavenging by Class A Receptors | 11 | 6.71e-03 | -0.472000 | 2.67e-02 |
| RHOBTB2 GTPase cycle | 23 | 6.85e-03 | -0.326000 | 2.72e-02 |
| Attenuation phase | 21 | 7.27e-03 | -0.338000 | 2.88e-02 |
| Intra-Golgi traffic | 40 | 7.32e-03 | -0.245000 | 2.89e-02 |
| Antigen processing: Ubiquitination & Proteasome degradation | 279 | 7.42e-03 | -0.093400 | 2.92e-02 |
| PERK regulates gene expression | 31 | 7.50e-03 | -0.278000 | 2.94e-02 |
| RHOC GTPase cycle | 67 | 7.55e-03 | -0.189000 | 2.95e-02 |
| Defective pyroptosis | 13 | 7.60e-03 | 0.428000 | 2.96e-02 |
| Nephrin family interactions | 17 | 7.65e-03 | -0.374000 | 2.97e-02 |
| RIP-mediated NFkB activation via ZBP1 | 14 | 7.78e-03 | -0.411000 | 3.02e-02 |
| RUNX3 regulates p14-ARF | 10 | 7.93e-03 | -0.485000 | 3.07e-02 |
| SCF(Skp2)-mediated degradation of p27/p21 | 58 | 7.96e-03 | -0.202000 | 3.07e-02 |
| Carboxyterminal post-translational modifications of tubulin | 30 | 8.12e-03 | 0.279000 | 3.10e-02 |
| FCGR3A-mediated phagocytosis | 47 | 8.13e-03 | -0.223000 | 3.10e-02 |
| Leishmania phagocytosis | 47 | 8.13e-03 | -0.223000 | 3.10e-02 |
| Parasite infection | 47 | 8.13e-03 | -0.223000 | 3.10e-02 |
| Activated NOTCH1 Transmits Signal to the Nucleus | 25 | 8.25e-03 | -0.305000 | 3.14e-02 |
| RHOA GTPase cycle | 129 | 8.29e-03 | -0.135000 | 3.14e-02 |
| Suppression of phagosomal maturation | 12 | 8.36e-03 | -0.440000 | 3.16e-02 |
| RHOJ GTPase cycle | 49 | 8.57e-03 | -0.217000 | 3.23e-02 |
| Ethanol oxidation | 10 | 8.67e-03 | 0.479000 | 3.25e-02 |
| Integrin cell surface interactions | 45 | 8.68e-03 | 0.226000 | 3.25e-02 |
| RHOB GTPase cycle | 63 | 8.68e-03 | -0.191000 | 3.25e-02 |
| Insulin receptor signalling cascade | 37 | 8.80e-03 | -0.249000 | 3.28e-02 |
| Cellular response to heat stress | 91 | 9.35e-03 | -0.158000 | 3.48e-02 |
| ATF6 (ATF6-alpha) activates chaperone genes | 10 | 9.43e-03 | -0.474000 | 3.50e-02 |
| ERK/MAPK targets | 21 | 9.53e-03 | -0.327000 | 3.53e-02 |
| FOXO-mediated transcription | 52 | 9.66e-03 | -0.208000 | 3.57e-02 |
| Signaling by FGFR1 | 38 | 9.69e-03 | -0.243000 | 3.57e-02 |
| Interleukin-12 family signaling | 46 | 9.79e-03 | -0.220000 | 3.59e-02 |
| Sphingolipid metabolism | 77 | 9.83e-03 | -0.170000 | 3.59e-02 |
| M Phase | 339 | 9.84e-03 | 0.081900 | 3.59e-02 |
| Regulation of PLK1 Activity at G2/M Transition | 84 | 9.91e-03 | 0.163000 | 3.61e-02 |
| Peroxisomal lipid metabolism | 26 | 9.99e-03 | 0.292000 | 3.63e-02 |
| RET signaling | 34 | 1.05e-02 | -0.254000 | 3.79e-02 |
| CDC42 GTPase cycle | 130 | 1.05e-02 | -0.130000 | 3.79e-02 |
| CD28 co-stimulation | 26 | 1.07e-02 | -0.289000 | 3.85e-02 |
| TRAF6 mediated NF-kB activation | 22 | 1.08e-02 | -0.314000 | 3.89e-02 |
| Signaling by FGFR | 69 | 1.09e-02 | -0.177000 | 3.93e-02 |
| ATF6 (ATF6-alpha) activates chaperones | 12 | 1.10e-02 | -0.424000 | 3.93e-02 |
| Incretin synthesis, secretion, and inactivation | 13 | 1.10e-02 | -0.407000 | 3.93e-02 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | 16 | 1.12e-02 | -0.366000 | 3.99e-02 |
| NF-kB is activated and signals survival | 12 | 1.14e-02 | -0.422000 | 4.04e-02 |
| Asymmetric localization of PCP proteins | 58 | 1.14e-02 | -0.192000 | 4.04e-02 |
| MET activates RAS signaling | 10 | 1.15e-02 | -0.461000 | 4.07e-02 |
| ZBP1(DAI) mediated induction of type I IFNs | 17 | 1.21e-02 | -0.352000 | 4.26e-02 |
| Glyoxylate metabolism and glycine degradation | 27 | 1.22e-02 | 0.279000 | 4.27e-02 |
| Negative regulation of FGFR3 signaling | 21 | 1.24e-02 | -0.315000 | 4.34e-02 |
| Signaling by MET | 63 | 1.24e-02 | -0.182000 | 4.34e-02 |
| Negative regulation of MET activity | 18 | 1.25e-02 | -0.340000 | 4.37e-02 |
| FLT3 Signaling | 32 | 1.26e-02 | -0.255000 | 4.38e-02 |
| Common Pathway of Fibrin Clot Formation | 16 | 1.26e-02 | 0.360000 | 4.39e-02 |
| Death Receptor Signalling | 124 | 1.27e-02 | -0.130000 | 4.41e-02 |
| CD28 dependent PI3K/Akt signaling | 18 | 1.32e-02 | -0.337000 | 4.55e-02 |
| LDL clearance | 19 | 1.32e-02 | -0.328000 | 4.55e-02 |
| p75 NTR receptor-mediated signalling | 82 | 1.34e-02 | -0.158000 | 4.61e-02 |
| ERKs are inactivated | 13 | 1.35e-02 | -0.396000 | 4.61e-02 |
| Constitutive Signaling by AKT1 E17K in Cancer | 24 | 1.35e-02 | -0.291000 | 4.62e-02 |
| Signaling by ALK fusions and activated point mutants | 50 | 1.38e-02 | -0.201000 | 4.70e-02 |
| Signaling by ALK in cancer | 50 | 1.38e-02 | -0.201000 | 4.70e-02 |
| Metabolism of vitamins and cofactors | 160 | 1.40e-02 | 0.113000 | 4.76e-02 |
| HSF1-dependent transactivation | 30 | 1.44e-02 | -0.258000 | 4.86e-02 |
| Semaphorin interactions | 51 | 1.44e-02 | -0.198000 | 4.86e-02 |
| Constitutive Signaling by EGFRvIII | 14 | 1.47e-02 | -0.377000 | 4.94e-02 |
| Signaling by EGFRvIII in Cancer | 14 | 1.47e-02 | -0.377000 | 4.94e-02 |
| Regulation of PTEN gene transcription | 58 | 1.48e-02 | -0.185000 | 4.95e-02 |
| Spry regulation of FGF signaling | 16 | 1.48e-02 | -0.352000 | 4.95e-02 |
| Post-chaperonin tubulin folding pathway | 17 | 1.49e-02 | 0.341000 | 4.95e-02 |
| Degradation of cysteine and homocysteine | 12 | 1.51e-02 | 0.405000 | 5.03e-02 |
| rRNA processing in the mitochondrion | 21 | 1.53e-02 | 0.306000 | 5.04e-02 |
| RAF activation | 33 | 1.54e-02 | -0.244000 | 5.04e-02 |
| G1/S DNA Damage Checkpoints | 64 | 1.54e-02 | -0.175000 | 5.04e-02 |
| Programmed Cell Death | 177 | 1.54e-02 | -0.106000 | 5.04e-02 |
| Mitochondrial tRNA aminoacylation | 18 | 1.54e-02 | 0.330000 | 5.04e-02 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | 49 | 1.55e-02 | -0.200000 | 5.04e-02 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | 49 | 1.55e-02 | -0.200000 | 5.04e-02 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | 49 | 1.55e-02 | -0.200000 | 5.04e-02 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | 49 | 1.55e-02 | -0.200000 | 5.04e-02 |
| Signaling by NOTCH1 in Cancer | 49 | 1.55e-02 | -0.200000 | 5.04e-02 |
| RHOH GTPase cycle | 32 | 1.58e-02 | -0.247000 | 5.12e-02 |
| FCERI mediated MAPK activation | 25 | 1.58e-02 | -0.279000 | 5.12e-02 |
| Signaling by Nuclear Receptors | 197 | 1.59e-02 | -0.099800 | 5.14e-02 |
| mTORC1-mediated signalling | 24 | 1.60e-02 | -0.284000 | 5.14e-02 |
| RHOBTB1 GTPase cycle | 21 | 1.60e-02 | -0.304000 | 5.15e-02 |
| Constitutive Signaling by Aberrant PI3K in Cancer | 43 | 1.61e-02 | -0.212000 | 5.15e-02 |
| Synthesis of PIPs at the plasma membrane | 45 | 1.61e-02 | -0.207000 | 5.15e-02 |
| Telomere C-strand synthesis initiation | 13 | 1.61e-02 | 0.385000 | 5.15e-02 |
| RHOF GTPase cycle | 40 | 1.63e-02 | -0.220000 | 5.20e-02 |
| Effects of PIP2 hydrolysis | 18 | 1.69e-02 | -0.325000 | 5.36e-02 |
| Meiosis | 46 | 1.70e-02 | 0.204000 | 5.36e-02 |
| Signalling to RAS | 18 | 1.70e-02 | -0.325000 | 5.36e-02 |
| SHC1 events in EGFR signaling | 11 | 1.70e-02 | -0.416000 | 5.36e-02 |
| ER-Phagosome pathway | 79 | 1.73e-02 | -0.155000 | 5.43e-02 |
| MTOR signalling | 40 | 1.74e-02 | -0.217000 | 5.45e-02 |
| Ovarian tumor domain proteases | 36 | 1.81e-02 | -0.228000 | 5.66e-02 |
| Cyclin E associated events during G1/S transition | 80 | 1.87e-02 | -0.152000 | 5.83e-02 |
| Neddylation | 214 | 1.91e-02 | -0.093200 | 5.95e-02 |
| Prolonged ERK activation events | 12 | 1.93e-02 | -0.390000 | 5.98e-02 |
| Phosphorylation of the APC/C | 20 | 1.93e-02 | 0.302000 | 5.98e-02 |
| p75NTR signals via NF-kB | 15 | 2.00e-02 | -0.347000 | 6.18e-02 |
| tRNA processing in the mitochondrion | 17 | 2.04e-02 | 0.325000 | 6.29e-02 |
| Metabolism | 1696 | 2.04e-02 | 0.034600 | 6.29e-02 |
| Removal of the Flap Intermediate from the C-strand | 17 | 2.08e-02 | 0.324000 | 6.40e-02 |
| Tie2 Signaling | 14 | 2.13e-02 | -0.355000 | 6.52e-02 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | 10 | 2.13e-02 | -0.420000 | 6.52e-02 |
| Rab regulation of trafficking | 114 | 2.14e-02 | -0.125000 | 6.52e-02 |
| Sphingolipid de novo biosynthesis | 38 | 2.14e-02 | -0.216000 | 6.53e-02 |
| NOTCH1 Intracellular Domain Regulates Transcription | 42 | 2.17e-02 | -0.205000 | 6.59e-02 |
| HDACs deacetylate histones | 32 | 2.21e-02 | -0.234000 | 6.70e-02 |
| Metabolism of water-soluble vitamins and cofactors | 104 | 2.21e-02 | 0.130000 | 6.70e-02 |
| HDR through MMEJ (alt-NHEJ) | 10 | 2.23e-02 | 0.417000 | 6.75e-02 |
| Signaling by FGFR2 | 57 | 2.24e-02 | -0.175000 | 6.75e-02 |
| Pausing and recovery of Tat-mediated HIV elongation | 30 | 2.34e-02 | -0.239000 | 7.02e-02 |
| Tat-mediated HIV elongation arrest and recovery | 30 | 2.34e-02 | -0.239000 | 7.02e-02 |
| Costimulation by the CD28 family | 41 | 2.36e-02 | -0.204000 | 7.07e-02 |
| Regulation of BACH1 activity | 11 | 2.40e-02 | -0.393000 | 7.15e-02 |
| Formation of RNA Pol II elongation complex | 57 | 2.40e-02 | -0.173000 | 7.15e-02 |
| RNA Polymerase II Transcription Elongation | 57 | 2.40e-02 | -0.173000 | 7.15e-02 |
| DAP12 signaling | 21 | 2.41e-02 | -0.284000 | 7.15e-02 |
| Regulation of HSF1-mediated heat shock response | 74 | 2.42e-02 | -0.152000 | 7.18e-02 |
| Nicotinate metabolism | 23 | 2.46e-02 | 0.271000 | 7.28e-02 |
| Regulation of TP53 Activity through Phosphorylation | 88 | 2.48e-02 | 0.139000 | 7.32e-02 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | 24 | 2.50e-02 | 0.264000 | 7.35e-02 |
| Mitochondrial Fatty Acid Beta-Oxidation | 32 | 2.54e-02 | 0.228000 | 7.47e-02 |
| G1/S-Specific Transcription | 28 | 2.62e-02 | 0.243000 | 7.67e-02 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | 20 | 2.66e-02 | -0.286000 | 7.79e-02 |
| SLC-mediated transmembrane transport | 174 | 2.71e-02 | -0.097300 | 7.91e-02 |
| E2F mediated regulation of DNA replication | 22 | 2.72e-02 | 0.272000 | 7.92e-02 |
| Nicotinamide salvaging | 14 | 2.74e-02 | 0.341000 | 7.96e-02 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | 12 | 2.79e-02 | -0.367000 | 8.09e-02 |
| Signaling by ERBB2 | 42 | 2.82e-02 | -0.196000 | 8.17e-02 |
| Selective autophagy | 56 | 2.85e-02 | -0.169000 | 8.24e-02 |
| Methylation | 12 | 2.86e-02 | 0.365000 | 8.24e-02 |
| APC-Cdc20 mediated degradation of Nek2A | 26 | 2.93e-02 | 0.247000 | 8.41e-02 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | 12 | 2.96e-02 | -0.363000 | 8.46e-02 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | 12 | 2.96e-02 | -0.363000 | 8.46e-02 |
| RHO GTPases Activate Formins | 116 | 2.96e-02 | 0.117000 | 8.46e-02 |
| RND1 GTPase cycle | 37 | 2.99e-02 | -0.206000 | 8.52e-02 |
| Mitophagy | 27 | 3.00e-02 | -0.241000 | 8.53e-02 |
| DARPP-32 events | 20 | 3.01e-02 | -0.280000 | 8.54e-02 |
| Formation of TC-NER Pre-Incision Complex | 53 | 3.06e-02 | -0.172000 | 8.67e-02 |
| Cyclin A:Cdk2-associated events at S phase entry | 82 | 3.09e-02 | -0.138000 | 8.72e-02 |
| TAK1 activates NFkB by phosphorylation and activation of IKKs complex | 24 | 3.10e-02 | -0.254000 | 8.75e-02 |
| Transcriptional Regulation by TP53 | 351 | 3.11e-02 | -0.067200 | 8.76e-02 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | 64 | 3.17e-02 | -0.155000 | 8.92e-02 |
| Polo-like kinase mediated events | 16 | 3.26e-02 | 0.309000 | 9.14e-02 |
| Advanced glycosylation endproduct receptor signaling | 10 | 3.27e-02 | -0.390000 | 9.14e-02 |
| Kinesins | 37 | 3.28e-02 | 0.203000 | 9.15e-02 |
| IGF1R signaling cascade | 35 | 3.29e-02 | -0.208000 | 9.17e-02 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | 35 | 3.29e-02 | -0.208000 | 9.17e-02 |
| Assembly of active LPL and LIPC lipase complexes | 16 | 3.33e-02 | 0.307000 | 9.22e-02 |
| Signaling by NOTCH3 | 37 | 3.33e-02 | -0.202000 | 9.22e-02 |
| L1CAM interactions | 72 | 3.33e-02 | -0.145000 | 9.22e-02 |
| Cyclin A/B1/B2 associated events during G2/M transition | 24 | 3.35e-02 | 0.251000 | 9.24e-02 |
| EPHB-mediated forward signaling | 34 | 3.38e-02 | -0.210000 | 9.30e-02 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | 23 | 3.40e-02 | 0.255000 | 9.34e-02 |
| IRS-mediated signalling | 32 | 3.41e-02 | -0.216000 | 9.36e-02 |
| APC truncation mutants have impaired AXIN binding | 14 | 3.57e-02 | -0.324000 | 9.66e-02 |
| AXIN missense mutants destabilize the destruction complex | 14 | 3.57e-02 | -0.324000 | 9.66e-02 |
| Signaling by AMER1 mutants | 14 | 3.57e-02 | -0.324000 | 9.66e-02 |
| Signaling by APC mutants | 14 | 3.57e-02 | -0.324000 | 9.66e-02 |
| Signaling by AXIN mutants | 14 | 3.57e-02 | -0.324000 | 9.66e-02 |
| Truncations of AMER1 destabilize the destruction complex | 14 | 3.57e-02 | -0.324000 | 9.66e-02 |
| HATs acetylate histones | 78 | 3.57e-02 | -0.138000 | 9.66e-02 |
| RHOD GTPase cycle | 49 | 3.58e-02 | -0.173000 | 9.66e-02 |
| DNA Replication | 127 | 3.66e-02 | 0.108000 | 9.86e-02 |
| Defective EXT1 causes exostoses 1, TRPS2 and CHDS | 13 | 3.71e-02 | 0.334000 | 9.96e-02 |
| Defective EXT2 causes exostoses 2 | 13 | 3.71e-02 | 0.334000 | 9.96e-02 |
| Negative regulation of FGFR2 signaling | 21 | 3.72e-02 | -0.263000 | 9.98e-02 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | 20 | 3.74e-02 | 0.269000 | 1.00e-01 |
| Signaling by PDGFR in disease | 17 | 3.76e-02 | -0.291000 | 1.00e-01 |
| RHO GTPases Activate WASPs and WAVEs | 32 | 3.76e-02 | -0.212000 | 1.00e-01 |
| HIV elongation arrest and recovery | 32 | 3.78e-02 | -0.212000 | 1.00e-01 |
| Pausing and recovery of HIV elongation | 32 | 3.78e-02 | -0.212000 | 1.00e-01 |
| Diseases of mitotic cell cycle | 37 | 3.79e-02 | 0.197000 | 1.00e-01 |
| Trafficking and processing of endosomal TLR | 10 | 3.80e-02 | -0.379000 | 1.00e-01 |
| Phospholipid metabolism | 160 | 3.81e-02 | -0.095200 | 1.00e-01 |
| Sulfur amino acid metabolism | 26 | 3.87e-02 | 0.234000 | 1.02e-01 |
| RHOU GTPase cycle | 36 | 3.97e-02 | -0.198000 | 1.04e-01 |
| SUMOylation of intracellular receptors | 25 | 3.99e-02 | -0.237000 | 1.05e-01 |
| Cleavage of the damaged purine | 11 | 4.01e-02 | 0.357000 | 1.05e-01 |
| Depurination | 11 | 4.01e-02 | 0.357000 | 1.05e-01 |
| Recognition and association of DNA glycosylase with site containing an affected purine | 11 | 4.01e-02 | 0.357000 | 1.05e-01 |
| Platelet activation, signaling and aggregation | 189 | 4.04e-02 | -0.086600 | 1.05e-01 |
| G2/M Checkpoints | 130 | 4.06e-02 | 0.104000 | 1.05e-01 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | 20 | 4.06e-02 | 0.264000 | 1.05e-01 |
| Translation of Structural Proteins | 27 | 4.15e-02 | -0.227000 | 1.07e-01 |
| Collagen biosynthesis and modifying enzymes | 36 | 4.16e-02 | 0.196000 | 1.08e-01 |
| RNA Polymerase III Abortive And Retractive Initiation | 41 | 4.20e-02 | -0.184000 | 1.08e-01 |
| RNA Polymerase III Transcription | 41 | 4.20e-02 | -0.184000 | 1.08e-01 |
| FCERI mediated Ca+2 mobilization | 20 | 4.23e-02 | -0.262000 | 1.09e-01 |
| Defective B4GALT7 causes EDS, progeroid type | 14 | 4.47e-02 | 0.310000 | 1.15e-01 |
| PINK1-PRKN Mediated Mitophagy | 20 | 4.53e-02 | -0.259000 | 1.16e-01 |
| Negative regulation of FLT3 | 13 | 4.58e-02 | -0.320000 | 1.17e-01 |
| Diseases associated with N-glycosylation of proteins | 17 | 4.60e-02 | -0.280000 | 1.17e-01 |
| Antimicrobial peptides | 17 | 4.65e-02 | 0.279000 | 1.18e-01 |
| GPCR downstream signalling | 257 | 4.72e-02 | -0.072100 | 1.20e-01 |
| Reproduction | 56 | 4.72e-02 | 0.153000 | 1.20e-01 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | 27 | 4.77e-02 | -0.220000 | 1.21e-01 |
| Cytosolic sulfonation of small molecules | 20 | 4.81e-02 | 0.255000 | 1.21e-01 |
| Plasma lipoprotein clearance | 32 | 4.84e-02 | -0.202000 | 1.22e-01 |
| Assembly Of The HIV Virion | 16 | 4.84e-02 | -0.285000 | 1.22e-01 |
| Energy dependent regulation of mTOR by LKB1-AMPK | 28 | 4.85e-02 | -0.216000 | 1.22e-01 |
| GRB2 events in EGFR signaling | 10 | 4.86e-02 | -0.360000 | 1.22e-01 |
| FLT3 signaling in disease | 26 | 4.88e-02 | -0.223000 | 1.22e-01 |
| Metabolism of amino acids and derivatives | 315 | 4.88e-02 | -0.064800 | 1.22e-01 |
| Miscellaneous transport and binding events | 21 | 4.90e-02 | -0.248000 | 1.22e-01 |
| ALK mutants bind TKIs | 10 | 4.92e-02 | -0.359000 | 1.23e-01 |
| PI3K Cascade | 28 | 4.98e-02 | -0.214000 | 1.24e-01 |
| RNA Polymerase III Transcription Termination | 23 | 5.01e-02 | -0.236000 | 1.24e-01 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | 64 | 5.02e-02 | -0.142000 | 1.24e-01 |
| MHC class II antigen presentation | 84 | 5.02e-02 | -0.124000 | 1.24e-01 |
| Condensation of Prometaphase Chromosomes | 11 | 5.03e-02 | 0.341000 | 1.24e-01 |
| SHC-mediated cascade:FGFR4 | 10 | 5.07e-02 | -0.357000 | 1.25e-01 |
| Synthesis of DNA | 116 | 5.08e-02 | 0.105000 | 1.25e-01 |
| tRNA Aminoacylation | 24 | 5.18e-02 | 0.229000 | 1.27e-01 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | 28 | 5.21e-02 | -0.212000 | 1.28e-01 |
| Cell recruitment (pro-inflammatory response) | 19 | 5.28e-02 | 0.257000 | 1.29e-01 |
| Purinergic signaling in leishmaniasis infection | 19 | 5.28e-02 | 0.257000 | 1.29e-01 |
| Activation of HOX genes during differentiation | 52 | 5.31e-02 | -0.155000 | 1.29e-01 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | 52 | 5.31e-02 | -0.155000 | 1.29e-01 |
| Basigin interactions | 20 | 5.37e-02 | -0.249000 | 1.30e-01 |
| FOXO-mediated transcription of cell death genes | 15 | 5.49e-02 | -0.286000 | 1.33e-01 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | 31 | 5.52e-02 | -0.199000 | 1.34e-01 |
| Erythropoietin activates RAS | 13 | 5.53e-02 | -0.307000 | 1.34e-01 |
| Lysine catabolism | 12 | 5.56e-02 | 0.319000 | 1.34e-01 |
| Role of LAT2/NTAL/LAB on calcium mobilization | 12 | 5.70e-02 | -0.317000 | 1.37e-01 |
| Synthesis of substrates in N-glycan biosythesis | 49 | 5.77e-02 | -0.157000 | 1.38e-01 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | 23 | 5.77e-02 | -0.229000 | 1.38e-01 |
| SHC-mediated cascade:FGFR1 | 10 | 5.78e-02 | -0.346000 | 1.38e-01 |
| Intrinsic Pathway of Fibrin Clot Formation | 18 | 5.80e-02 | 0.258000 | 1.38e-01 |
| Estrogen-dependent gene expression | 84 | 5.80e-02 | -0.120000 | 1.38e-01 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | 35 | 5.81e-02 | 0.185000 | 1.38e-01 |
| RNA Polymerase II Pre-transcription Events | 78 | 5.82e-02 | -0.124000 | 1.38e-01 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | 25 | 5.95e-02 | -0.218000 | 1.41e-01 |
| FOXO-mediated transcription of cell cycle genes | 14 | 5.95e-02 | -0.291000 | 1.41e-01 |
| Activation of BAD and translocation to mitochondria | 14 | 5.98e-02 | -0.291000 | 1.41e-01 |
| PKMTs methylate histone lysines | 41 | 6.02e-02 | -0.170000 | 1.42e-01 |
| InlB-mediated entry of Listeria monocytogenes into host cell | 13 | 6.02e-02 | -0.301000 | 1.42e-01 |
| GPVI-mediated activation cascade | 22 | 6.03e-02 | -0.231000 | 1.42e-01 |
| Hedgehog ‘off’ state | 86 | 6.06e-02 | -0.117000 | 1.42e-01 |
| Signaling by ERBB4 | 42 | 6.06e-02 | -0.167000 | 1.42e-01 |
| IRS-related events triggered by IGF1R | 34 | 6.07e-02 | -0.186000 | 1.42e-01 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | 18 | 6.08e-02 | -0.255000 | 1.42e-01 |
| Downstream signaling of activated FGFR4 | 17 | 6.08e-02 | -0.263000 | 1.42e-01 |
| HS-GAG degradation | 18 | 6.10e-02 | 0.255000 | 1.42e-01 |
| CTLA4 inhibitory signaling | 17 | 6.14e-02 | -0.262000 | 1.43e-01 |
| Metabolism of nucleotides | 86 | 6.19e-02 | 0.117000 | 1.44e-01 |
| Vitamin B5 (pantothenate) metabolism | 16 | 6.20e-02 | 0.270000 | 1.44e-01 |
| Constitutive Signaling by Overexpressed ERBB2 | 11 | 6.33e-02 | -0.323000 | 1.46e-01 |
| TICAM1-dependent activation of IRF3/IRF7 | 10 | 6.40e-02 | -0.338000 | 1.48e-01 |
| Striated Muscle Contraction | 18 | 6.54e-02 | 0.251000 | 1.51e-01 |
| Pexophagy | 11 | 6.55e-02 | -0.321000 | 1.51e-01 |
| Glutathione synthesis and recycling | 12 | 6.59e-02 | 0.307000 | 1.51e-01 |
| S33 mutants of beta-catenin aren’t phosphorylated | 15 | 6.65e-02 | -0.274000 | 1.51e-01 |
| S37 mutants of beta-catenin aren’t phosphorylated | 15 | 6.65e-02 | -0.274000 | 1.51e-01 |
| S45 mutants of beta-catenin aren’t phosphorylated | 15 | 6.65e-02 | -0.274000 | 1.51e-01 |
| Signaling by CTNNB1 phospho-site mutants | 15 | 6.65e-02 | -0.274000 | 1.51e-01 |
| Signaling by GSK3beta mutants | 15 | 6.65e-02 | -0.274000 | 1.51e-01 |
| T41 mutants of beta-catenin aren’t phosphorylated | 15 | 6.65e-02 | -0.274000 | 1.51e-01 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | 21 | 6.67e-02 | -0.231000 | 1.52e-01 |
| Gastrin-CREB signalling pathway via PKC and MAPK | 16 | 6.80e-02 | -0.264000 | 1.54e-01 |
| Recycling pathway of L1 | 24 | 6.86e-02 | -0.215000 | 1.55e-01 |
| Signaling by ERBB2 ECD mutants | 15 | 6.95e-02 | -0.271000 | 1.57e-01 |
| WNT5A-dependent internalization of FZD4 | 12 | 7.08e-02 | -0.301000 | 1.60e-01 |
| Fatty acyl-CoA biosynthesis | 29 | 7.11e-02 | 0.194000 | 1.60e-01 |
| Deadenylation of mRNA | 24 | 7.24e-02 | -0.212000 | 1.63e-01 |
| Metabolism of steroids | 130 | 7.27e-02 | 0.091300 | 1.63e-01 |
| HSF1 activation | 24 | 7.33e-02 | -0.211000 | 1.64e-01 |
| Autodegradation of Cdh1 by Cdh1:APC/C | 63 | 7.39e-02 | -0.130000 | 1.65e-01 |
| Signal transduction by L1 | 18 | 7.41e-02 | -0.243000 | 1.65e-01 |
| PCNA-Dependent Long Patch Base Excision Repair | 21 | 7.41e-02 | 0.225000 | 1.65e-01 |
| CDK-mediated phosphorylation and removal of Cdc6 | 69 | 7.48e-02 | -0.124000 | 1.67e-01 |
| RAF-independent MAPK1/3 activation | 21 | 7.79e-02 | -0.222000 | 1.73e-01 |
| SHC1 events in ERBB2 signaling | 15 | 7.86e-02 | -0.262000 | 1.74e-01 |
| CD209 (DC-SIGN) signaling | 18 | 7.96e-02 | -0.239000 | 1.76e-01 |
| Keratinization | 29 | 8.01e-02 | -0.188000 | 1.77e-01 |
| Signaling by ERBB2 in Cancer | 19 | 8.02e-02 | -0.232000 | 1.77e-01 |
| Cytochrome P450 - arranged by substrate type | 44 | 8.11e-02 | 0.152000 | 1.79e-01 |
| Synthesis of PA | 25 | 8.13e-02 | 0.201000 | 1.79e-01 |
| Assembly of collagen fibrils and other multimeric structures | 34 | 8.13e-02 | 0.173000 | 1.79e-01 |
| TICAM1, RIP1-mediated IKK complex recruitment | 17 | 8.17e-02 | -0.244000 | 1.79e-01 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | 25 | 8.18e-02 | 0.201000 | 1.79e-01 |
| PI-3K cascade:FGFR4 | 10 | 8.22e-02 | -0.317000 | 1.80e-01 |
| SUMOylation of transcription cofactors | 43 | 8.25e-02 | -0.153000 | 1.80e-01 |
| S Phase | 157 | 8.27e-02 | 0.080400 | 1.81e-01 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | 45 | 8.32e-02 | -0.149000 | 1.81e-01 |
| Golgi-to-ER retrograde transport | 106 | 8.47e-02 | -0.097000 | 1.84e-01 |
| Beta-catenin phosphorylation cascade | 17 | 8.52e-02 | -0.241000 | 1.85e-01 |
| Gamma-carboxylation, transport, and amino-terminal cleavage of proteins | 10 | 8.67e-02 | 0.313000 | 1.88e-01 |
| p75NTR recruits signalling complexes | 12 | 8.71e-02 | -0.285000 | 1.89e-01 |
| Peptide hormone metabolism | 50 | 8.72e-02 | -0.140000 | 1.89e-01 |
| Synthesis of PIPs at the early endosome membrane | 15 | 8.82e-02 | -0.254000 | 1.90e-01 |
| Generation of second messenger molecules | 14 | 8.83e-02 | -0.263000 | 1.90e-01 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | 27 | 8.88e-02 | -0.189000 | 1.91e-01 |
| Formation of Incision Complex in GG-NER | 43 | 8.95e-02 | 0.150000 | 1.92e-01 |
| N-glycan antennae elongation in the medial/trans-Golgi | 19 | 9.13e-02 | -0.224000 | 1.96e-01 |
| CDC6 association with the ORC:origin complex | 11 | 9.19e-02 | 0.293000 | 1.97e-01 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | 34 | 9.21e-02 | -0.167000 | 1.97e-01 |
| Repression of WNT target genes | 12 | 9.21e-02 | -0.281000 | 1.97e-01 |
| GPCR ligand binding | 128 | 9.25e-02 | 0.086200 | 1.97e-01 |
| PI-3K cascade:FGFR1 | 10 | 9.28e-02 | -0.307000 | 1.97e-01 |
| RORA activates gene expression | 18 | 9.32e-02 | -0.229000 | 1.98e-01 |
| WNT ligand biogenesis and trafficking | 11 | 9.34e-02 | -0.292000 | 1.98e-01 |
| Transport of vitamins, nucleosides, and related molecules | 33 | 9.36e-02 | 0.169000 | 1.98e-01 |
| Protein-protein interactions at synapses | 52 | 9.40e-02 | 0.134000 | 1.99e-01 |
| HS-GAG biosynthesis | 22 | 9.43e-02 | 0.206000 | 1.99e-01 |
| Cell-Cell communication | 90 | 9.47e-02 | -0.102000 | 2.00e-01 |
| Signaling by PDGFRA extracellular domain mutants | 11 | 9.60e-02 | -0.290000 | 2.02e-01 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | 11 | 9.60e-02 | -0.290000 | 2.02e-01 |
| Frs2-mediated activation | 10 | 9.64e-02 | -0.304000 | 2.02e-01 |
| Positive epigenetic regulation of rRNA expression | 44 | 9.68e-02 | -0.145000 | 2.03e-01 |
| Hemostasis | 409 | 9.69e-02 | -0.048100 | 2.03e-01 |
| Oncogenic MAPK signaling | 72 | 9.76e-02 | -0.113000 | 2.04e-01 |
| DAP12 interactions | 24 | 9.89e-02 | -0.195000 | 2.06e-01 |
| Signaling by Erythropoietin | 22 | 9.92e-02 | -0.203000 | 2.07e-01 |
| Acyl chain remodelling of PC | 11 | 1.00e-01 | 0.286000 | 2.09e-01 |
| Defects in cobalamin (B12) metabolism | 12 | 1.01e-01 | 0.273000 | 2.10e-01 |
| Signaling by GPCR | 289 | 1.01e-01 | -0.056200 | 2.10e-01 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | 13 | 1.02e-01 | -0.262000 | 2.12e-01 |
| Mitotic Anaphase | 221 | 1.03e-01 | 0.063900 | 2.12e-01 |
| Signaling by FLT3 ITD and TKD mutants | 14 | 1.07e-01 | -0.249000 | 2.20e-01 |
| Termination of translesion DNA synthesis | 32 | 1.07e-01 | 0.165000 | 2.20e-01 |
| Insulin processing | 22 | 1.07e-01 | -0.199000 | 2.20e-01 |
| Chaperone Mediated Autophagy | 17 | 1.08e-01 | -0.225000 | 2.22e-01 |
| Separation of Sister Chromatids | 165 | 1.08e-01 | 0.072600 | 2.22e-01 |
| APC/C:Cdc20 mediated degradation of Securin | 65 | 1.08e-01 | -0.115000 | 2.22e-01 |
| COPI-dependent Golgi-to-ER retrograde traffic | 75 | 1.09e-01 | -0.107000 | 2.22e-01 |
| ATF4 activates genes in response to endoplasmic reticulum stress | 26 | 1.09e-01 | -0.182000 | 2.22e-01 |
| ABC transporters in lipid homeostasis | 14 | 1.09e-01 | 0.248000 | 2.22e-01 |
| Disorders of Developmental Biology | 12 | 1.12e-01 | -0.265000 | 2.26e-01 |
| Disorders of Nervous System Development | 12 | 1.12e-01 | -0.265000 | 2.26e-01 |
| Loss of function of MECP2 in Rett syndrome | 12 | 1.12e-01 | -0.265000 | 2.26e-01 |
| Pervasive developmental disorders | 12 | 1.12e-01 | -0.265000 | 2.26e-01 |
| APC/C:Cdc20 mediated degradation of Cyclin B | 24 | 1.12e-01 | 0.188000 | 2.26e-01 |
| Signaling by FGFR3 fusions in cancer | 10 | 1.12e-01 | -0.290000 | 2.26e-01 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | 33 | 1.12e-01 | -0.160000 | 2.26e-01 |
| Mitochondrial biogenesis | 71 | 1.14e-01 | -0.108000 | 2.30e-01 |
| Metabolic disorders of biological oxidation enzymes | 27 | 1.14e-01 | 0.176000 | 2.30e-01 |
| Cardiac conduction | 66 | 1.15e-01 | -0.112000 | 2.32e-01 |
| Mitotic Metaphase and Anaphase | 222 | 1.15e-01 | 0.061500 | 2.32e-01 |
| mRNA 3’-end processing | 56 | 1.16e-01 | -0.121000 | 2.33e-01 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | 11 | 1.17e-01 | -0.273000 | 2.35e-01 |
| RNA Polymerase II Transcription Termination | 65 | 1.18e-01 | -0.112000 | 2.35e-01 |
| G0 and Early G1 | 26 | 1.19e-01 | 0.177000 | 2.38e-01 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | 29 | 1.19e-01 | -0.167000 | 2.38e-01 |
| A tetrasaccharide linker sequence is required for GAG synthesis | 18 | 1.20e-01 | 0.212000 | 2.39e-01 |
| Late Phase of HIV Life Cycle | 132 | 1.21e-01 | -0.078300 | 2.40e-01 |
| Myogenesis | 19 | 1.21e-01 | -0.206000 | 2.40e-01 |
| Regulation of IFNA signaling | 12 | 1.21e-01 | 0.258000 | 2.40e-01 |
| Extracellular matrix organization | 183 | 1.22e-01 | 0.066500 | 2.40e-01 |
| Downstream signal transduction | 28 | 1.22e-01 | -0.169000 | 2.40e-01 |
| Biotin transport and metabolism | 11 | 1.22e-01 | -0.269000 | 2.40e-01 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | 42 | 1.22e-01 | -0.138000 | 2.41e-01 |
| HIV Transcription Elongation | 42 | 1.22e-01 | -0.138000 | 2.41e-01 |
| Tat-mediated elongation of the HIV-1 transcript | 42 | 1.22e-01 | -0.138000 | 2.41e-01 |
| Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon | 14 | 1.23e-01 | -0.238000 | 2.41e-01 |
| Downstream signaling of activated FGFR3 | 17 | 1.23e-01 | -0.216000 | 2.41e-01 |
| Defective B3GAT3 causes JDSSDHD | 14 | 1.23e-01 | 0.238000 | 2.41e-01 |
| G alpha (q) signalling events | 93 | 1.23e-01 | -0.092500 | 2.41e-01 |
| RHO GTPases activate PAKs | 20 | 1.24e-01 | -0.199000 | 2.42e-01 |
| Neurexins and neuroligins | 36 | 1.24e-01 | 0.148000 | 2.42e-01 |
| IKK complex recruitment mediated by RIP1 | 20 | 1.25e-01 | -0.198000 | 2.43e-01 |
| Diseases associated with glycosaminoglycan metabolism | 29 | 1.25e-01 | 0.164000 | 2.44e-01 |
| B-WICH complex positively regulates rRNA expression | 29 | 1.26e-01 | -0.164000 | 2.45e-01 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | 16 | 1.27e-01 | 0.221000 | 2.45e-01 |
| Retinoid metabolism and transport | 35 | 1.28e-01 | 0.149000 | 2.48e-01 |
| SHC-mediated cascade:FGFR3 | 10 | 1.28e-01 | -0.278000 | 2.48e-01 |
| Arachidonic acid metabolism | 30 | 1.31e-01 | 0.160000 | 2.52e-01 |
| Assembly of the pre-replicative complex | 69 | 1.32e-01 | -0.105000 | 2.55e-01 |
| FRS-mediated FGFR4 signaling | 12 | 1.34e-01 | -0.250000 | 2.57e-01 |
| Binding and Uptake of Ligands by Scavenger Receptors | 27 | 1.34e-01 | -0.167000 | 2.57e-01 |
| Netrin-1 signaling | 35 | 1.34e-01 | -0.146000 | 2.58e-01 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | 23 | 1.34e-01 | -0.180000 | 2.58e-01 |
| Formation of the beta-catenin:TCF transactivating complex | 30 | 1.35e-01 | -0.158000 | 2.58e-01 |
| Signaling by ERBB2 KD Mutants | 18 | 1.36e-01 | -0.203000 | 2.60e-01 |
| SUMOylation of immune response proteins | 11 | 1.37e-01 | -0.259000 | 2.61e-01 |
| Interleukin receptor SHC signaling | 17 | 1.38e-01 | -0.208000 | 2.62e-01 |
| Heparan sulfate/heparin (HS-GAG) metabolism | 36 | 1.38e-01 | 0.143000 | 2.63e-01 |
| MECP2 regulates neuronal receptors and channels | 13 | 1.39e-01 | -0.237000 | 2.64e-01 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | 12 | 1.39e-01 | 0.246000 | 2.64e-01 |
| alpha-linolenic acid (ALA) metabolism | 12 | 1.39e-01 | 0.246000 | 2.64e-01 |
| Regulation of TNFR1 signaling | 34 | 1.39e-01 | -0.147000 | 2.64e-01 |
| Elastic fibre formation | 28 | 1.43e-01 | 0.160000 | 2.69e-01 |
| Signaling by FGFR4 in disease | 11 | 1.45e-01 | -0.254000 | 2.73e-01 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | 10 | 1.45e-01 | -0.266000 | 2.73e-01 |
| Plasma lipoprotein remodeling | 29 | 1.46e-01 | 0.156000 | 2.75e-01 |
| GABA synthesis, release, reuptake and degradation | 11 | 1.47e-01 | -0.253000 | 2.76e-01 |
| Ephrin signaling | 15 | 1.48e-01 | -0.216000 | 2.76e-01 |
| FRS-mediated FGFR1 signaling | 12 | 1.48e-01 | -0.241000 | 2.76e-01 |
| MAP2K and MAPK activation | 34 | 1.48e-01 | -0.143000 | 2.77e-01 |
| Endogenous sterols | 22 | 1.49e-01 | 0.178000 | 2.77e-01 |
| Pyrimidine salvage | 10 | 1.49e-01 | 0.264000 | 2.78e-01 |
| Dual Incision in GG-NER | 41 | 1.50e-01 | 0.130000 | 2.79e-01 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | 14 | 1.51e-01 | 0.222000 | 2.81e-01 |
| Signaling by high-kinase activity BRAF mutants | 30 | 1.52e-01 | -0.151000 | 2.82e-01 |
| p38MAPK events | 13 | 1.52e-01 | -0.230000 | 2.82e-01 |
| Global Genome Nucleotide Excision Repair (GG-NER) | 84 | 1.52e-01 | 0.090500 | 2.82e-01 |
| N-Glycan antennae elongation | 12 | 1.52e-01 | -0.239000 | 2.82e-01 |
| Mitochondrial iron-sulfur cluster biogenesis | 13 | 1.53e-01 | 0.229000 | 2.82e-01 |
| IRAK1 recruits IKK complex | 10 | 1.53e-01 | -0.261000 | 2.82e-01 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | 10 | 1.53e-01 | -0.261000 | 2.82e-01 |
| RNA Polymerase III Transcription Initiation | 36 | 1.53e-01 | -0.138000 | 2.82e-01 |
| Epigenetic regulation of gene expression | 85 | 1.53e-01 | -0.089700 | 2.82e-01 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | 38 | 1.54e-01 | -0.134000 | 2.82e-01 |
| Signaling by RAS mutants | 38 | 1.54e-01 | -0.134000 | 2.82e-01 |
| Signaling by moderate kinase activity BRAF mutants | 38 | 1.54e-01 | -0.134000 | 2.82e-01 |
| Signaling downstream of RAS mutants | 38 | 1.54e-01 | -0.134000 | 2.82e-01 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | 25 | 1.57e-01 | -0.164000 | 2.86e-01 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | 17 | 1.57e-01 | -0.198000 | 2.87e-01 |
| Formation of HIV elongation complex in the absence of HIV Tat | 44 | 1.59e-01 | -0.123000 | 2.89e-01 |
| Platelet calcium homeostasis | 15 | 1.59e-01 | -0.210000 | 2.90e-01 |
| activated TAK1 mediates p38 MAPK activation | 18 | 1.62e-01 | -0.190000 | 2.94e-01 |
| Signaling by Non-Receptor Tyrosine Kinases | 44 | 1.63e-01 | -0.122000 | 2.95e-01 |
| Signaling by PTK6 | 44 | 1.63e-01 | -0.122000 | 2.95e-01 |
| EPH-ephrin mediated repulsion of cells | 38 | 1.64e-01 | -0.131000 | 2.96e-01 |
| Defective B3GALTL causes PpS | 19 | 1.64e-01 | 0.184000 | 2.97e-01 |
| Membrane binding and targetting of GAG proteins | 14 | 1.66e-01 | -0.214000 | 2.99e-01 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | 14 | 1.66e-01 | -0.214000 | 2.99e-01 |
| Nucleotide salvage | 20 | 1.66e-01 | 0.179000 | 2.99e-01 |
| GAB1 signalosome | 14 | 1.66e-01 | -0.214000 | 2.99e-01 |
| Transcriptional regulation of white adipocyte differentiation | 74 | 1.67e-01 | -0.092900 | 3.00e-01 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | 54 | 1.67e-01 | 0.109000 | 3.00e-01 |
| Transport of bile salts and organic acids, metal ions and amine compounds | 58 | 1.70e-01 | -0.104000 | 3.04e-01 |
| Class A/1 (Rhodopsin-like receptors) | 84 | 1.70e-01 | 0.086700 | 3.04e-01 |
| Retrograde neurotrophin signalling | 10 | 1.70e-01 | -0.250000 | 3.04e-01 |
| SUMOylation of DNA replication proteins | 45 | 1.71e-01 | 0.118000 | 3.04e-01 |
| Regulation of TP53 Activity through Methylation | 19 | 1.75e-01 | -0.180000 | 3.11e-01 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | 13 | 1.76e-01 | 0.217000 | 3.13e-01 |
| Glycosphingolipid metabolism | 39 | 1.76e-01 | -0.125000 | 3.13e-01 |
| PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases | 14 | 1.78e-01 | -0.208000 | 3.16e-01 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | 11 | 1.80e-01 | 0.234000 | 3.18e-01 |
| Diseases of hemostasis | 11 | 1.80e-01 | 0.234000 | 3.18e-01 |
| Leishmania infection | 133 | 1.81e-01 | -0.067300 | 3.20e-01 |
| O-glycosylation of TSR domain-containing proteins | 20 | 1.82e-01 | 0.172000 | 3.21e-01 |
| RHO GTPases activate KTN1 | 11 | 1.82e-01 | -0.232000 | 3.21e-01 |
| MET promotes cell motility | 27 | 1.84e-01 | -0.148000 | 3.24e-01 |
| Synthesis of bile acids and bile salts via 27-hydroxycholesterol | 14 | 1.84e-01 | -0.205000 | 3.24e-01 |
| Diseases associated with the TLR signaling cascade | 22 | 1.85e-01 | 0.163000 | 3.24e-01 |
| Diseases of Immune System | 22 | 1.85e-01 | 0.163000 | 3.24e-01 |
| Budding and maturation of HIV virion | 28 | 1.86e-01 | -0.145000 | 3.25e-01 |
| Receptor Mediated Mitophagy | 10 | 1.86e-01 | -0.242000 | 3.25e-01 |
| Signaling by FGFR3 in disease | 14 | 1.89e-01 | -0.203000 | 3.29e-01 |
| Signaling by FGFR3 point mutants in cancer | 14 | 1.89e-01 | -0.203000 | 3.29e-01 |
| RHO GTPases Activate ROCKs | 19 | 1.89e-01 | -0.174000 | 3.29e-01 |
| Regulation of gene expression by Hypoxia-inducible Factor | 11 | 1.90e-01 | -0.228000 | 3.30e-01 |
| Phenylalanine and tyrosine metabolism | 10 | 1.90e-01 | 0.239000 | 3.31e-01 |
| Nucleotide biosynthesis | 14 | 1.91e-01 | 0.202000 | 3.31e-01 |
| Transport of Mature Transcript to Cytoplasm | 80 | 1.92e-01 | -0.084500 | 3.32e-01 |
| PI-3K cascade:FGFR3 | 10 | 1.92e-01 | -0.238000 | 3.32e-01 |
| Transcriptional Regulation by VENTX | 35 | 1.92e-01 | 0.127000 | 3.32e-01 |
| Nuclear events stimulated by ALK signaling in cancer | 17 | 1.92e-01 | -0.183000 | 3.32e-01 |
| Signaling by WNT in cancer | 32 | 1.92e-01 | -0.133000 | 3.32e-01 |
| Glucagon-type ligand receptors | 11 | 1.94e-01 | 0.226000 | 3.35e-01 |
| Visual phototransduction | 68 | 1.96e-01 | 0.090800 | 3.37e-01 |
| Sensory Perception | 134 | 1.97e-01 | 0.064600 | 3.39e-01 |
| Organic cation/anion/zwitterion transport | 11 | 1.98e-01 | -0.224000 | 3.39e-01 |
| Signaling by FLT3 fusion proteins | 18 | 1.98e-01 | -0.175000 | 3.40e-01 |
| Cell death signalling via NRAGE, NRIF and NADE | 65 | 1.99e-01 | -0.092100 | 3.42e-01 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | 13 | 2.00e-01 | -0.205000 | 3.42e-01 |
| Apoptotic cleavage of cellular proteins | 31 | 2.01e-01 | -0.133000 | 3.43e-01 |
| Ion transport by P-type ATPases | 36 | 2.04e-01 | -0.122000 | 3.48e-01 |
| Late endosomal microautophagy | 29 | 2.04e-01 | -0.136000 | 3.48e-01 |
| VEGFR2 mediated vascular permeability | 22 | 2.05e-01 | -0.156000 | 3.48e-01 |
| Glucagon signaling in metabolic regulation | 19 | 2.05e-01 | 0.168000 | 3.48e-01 |
| Carnitine metabolism | 11 | 2.05e-01 | 0.220000 | 3.49e-01 |
| Signaling by ERBB2 TMD/JMD mutants | 15 | 2.06e-01 | -0.189000 | 3.49e-01 |
| Association of TriC/CCT with target proteins during biosynthesis | 38 | 2.07e-01 | -0.118000 | 3.51e-01 |
| Opioid Signalling | 60 | 2.08e-01 | -0.093900 | 3.53e-01 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | 11 | 2.10e-01 | 0.218000 | 3.54e-01 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | 71 | 2.10e-01 | -0.086100 | 3.54e-01 |
| Activation of BH3-only proteins | 28 | 2.10e-01 | -0.137000 | 3.54e-01 |
| Cell junction organization | 64 | 2.10e-01 | -0.090600 | 3.54e-01 |
| Regulation of gene expression in beta cells | 13 | 2.11e-01 | 0.201000 | 3.54e-01 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | 13 | 2.11e-01 | 0.200000 | 3.55e-01 |
| Diseases of programmed cell death | 41 | 2.12e-01 | 0.113000 | 3.55e-01 |
| Hyaluronan metabolism | 13 | 2.13e-01 | -0.199000 | 3.57e-01 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | 17 | 2.14e-01 | -0.174000 | 3.59e-01 |
| The canonical retinoid cycle in rods (twilight vision) | 16 | 2.15e-01 | 0.179000 | 3.59e-01 |
| Synthesis of bile acids and bile salts | 31 | 2.17e-01 | -0.128000 | 3.63e-01 |
| RAB geranylgeranylation | 52 | 2.18e-01 | -0.098900 | 3.63e-01 |
| Synthesis of IP3 and IP4 in the cytosol | 20 | 2.18e-01 | -0.159000 | 3.64e-01 |
| Orc1 removal from chromatin | 67 | 2.24e-01 | -0.085900 | 3.73e-01 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | 14 | 2.25e-01 | 0.187000 | 3.73e-01 |
| Sema4D in semaphorin signaling | 24 | 2.25e-01 | -0.143000 | 3.73e-01 |
| Mitochondrial translation | 93 | 2.27e-01 | -0.072600 | 3.75e-01 |
| Glycolysis | 65 | 2.27e-01 | -0.086700 | 3.76e-01 |
| Deactivation of the beta-catenin transactivating complex | 38 | 2.30e-01 | -0.113000 | 3.81e-01 |
| Interleukin-20 family signaling | 15 | 2.32e-01 | 0.178000 | 3.83e-01 |
| Olfactory Signaling Pathway | 14 | 2.33e-01 | 0.184000 | 3.85e-01 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | 42 | 2.40e-01 | 0.105000 | 3.95e-01 |
| HIV Life Cycle | 143 | 2.42e-01 | -0.056800 | 3.97e-01 |
| Aggrephagy | 20 | 2.42e-01 | -0.151000 | 3.97e-01 |
| Transcriptional regulation of granulopoiesis | 25 | 2.42e-01 | -0.135000 | 3.97e-01 |
| Cell surface interactions at the vascular wall | 86 | 2.42e-01 | -0.073000 | 3.97e-01 |
| RNA Polymerase III Chain Elongation | 18 | 2.43e-01 | -0.159000 | 3.97e-01 |
| Antiviral mechanism by IFN-stimulated genes | 77 | 2.44e-01 | -0.076900 | 3.99e-01 |
| Sensory perception of taste | 13 | 2.45e-01 | 0.186000 | 3.99e-01 |
| MicroRNA (miRNA) biogenesis | 24 | 2.45e-01 | -0.137000 | 3.99e-01 |
| Chondroitin sulfate biosynthesis | 14 | 2.45e-01 | -0.180000 | 3.99e-01 |
| Regulated proteolysis of p75NTR | 11 | 2.46e-01 | -0.202000 | 4.00e-01 |
| NRAGE signals death through JNK | 48 | 2.47e-01 | -0.096700 | 4.01e-01 |
| Transcriptional activation of mitochondrial biogenesis | 50 | 2.50e-01 | -0.094100 | 4.06e-01 |
| TRAF6 mediated IRF7 activation | 15 | 2.50e-01 | -0.171000 | 4.06e-01 |
| tRNA processing | 114 | 2.53e-01 | 0.062100 | 4.09e-01 |
| Keratan sulfate/keratin metabolism | 25 | 2.53e-01 | -0.132000 | 4.09e-01 |
| Synthesis of bile acids and bile salts via 24-hydroxycholesterol | 14 | 2.55e-01 | -0.176000 | 4.12e-01 |
| Mitochondrial translation termination | 87 | 2.56e-01 | -0.070500 | 4.14e-01 |
| CLEC7A (Dectin-1) induces NFAT activation | 10 | 2.57e-01 | -0.207000 | 4.15e-01 |
| Interferon alpha/beta signaling | 45 | 2.57e-01 | 0.097600 | 4.15e-01 |
| Synthesis of glycosylphosphatidylinositol (GPI) | 18 | 2.58e-01 | 0.154000 | 4.15e-01 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | 48 | 2.58e-01 | -0.094400 | 4.15e-01 |
| Signal regulatory protein family interactions | 10 | 2.59e-01 | 0.206000 | 4.16e-01 |
| The role of Nef in HIV-1 replication and disease pathogenesis | 23 | 2.60e-01 | -0.136000 | 4.16e-01 |
| RUNX3 regulates NOTCH signaling | 12 | 2.62e-01 | -0.187000 | 4.19e-01 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | 30 | 2.63e-01 | -0.118000 | 4.20e-01 |
| Pre-NOTCH Expression and Processing | 46 | 2.63e-01 | -0.095400 | 4.20e-01 |
| FGFR2 alternative splicing | 25 | 2.63e-01 | -0.129000 | 4.20e-01 |
| Nonhomologous End-Joining (NHEJ) | 34 | 2.64e-01 | 0.111000 | 4.20e-01 |
| Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane | 11 | 2.64e-01 | 0.195000 | 4.20e-01 |
| SUMOylation | 162 | 2.65e-01 | -0.050900 | 4.21e-01 |
| VEGFR2 mediated cell proliferation | 17 | 2.66e-01 | -0.156000 | 4.23e-01 |
| Transcription of the HIV genome | 67 | 2.67e-01 | -0.078500 | 4.24e-01 |
| FRS-mediated FGFR3 signaling | 12 | 2.69e-01 | -0.184000 | 4.27e-01 |
| Prostacyclin signalling through prostacyclin receptor | 10 | 2.70e-01 | 0.201000 | 4.27e-01 |
| RAB GEFs exchange GTP for GDP on RABs | 82 | 2.71e-01 | -0.070500 | 4.27e-01 |
| Apoptotic execution phase | 39 | 2.71e-01 | -0.102000 | 4.27e-01 |
| NR1H2 and NR1H3-mediated signaling | 40 | 2.74e-01 | -0.099900 | 4.33e-01 |
| Nuclear Pore Complex (NPC) Disassembly | 35 | 2.75e-01 | 0.107000 | 4.33e-01 |
| RNA polymerase II transcribes snRNA genes | 71 | 2.76e-01 | -0.074800 | 4.35e-01 |
| VLDLR internalisation and degradation | 12 | 2.77e-01 | -0.181000 | 4.35e-01 |
| Inositol phosphate metabolism | 37 | 2.78e-01 | -0.103000 | 4.37e-01 |
| PRC2 methylates histones and DNA | 14 | 2.79e-01 | 0.167000 | 4.38e-01 |
| Cristae formation | 13 | 2.79e-01 | -0.173000 | 4.38e-01 |
| Pre-NOTCH Processing in Golgi | 16 | 2.81e-01 | -0.156000 | 4.39e-01 |
| Downstream signaling of activated FGFR2 | 17 | 2.81e-01 | -0.151000 | 4.39e-01 |
| Dissolution of Fibrin Clot | 12 | 2.81e-01 | 0.180000 | 4.39e-01 |
| Signaling by cytosolic FGFR1 fusion mutants | 17 | 2.85e-01 | -0.150000 | 4.45e-01 |
| NRIF signals cell death from the nucleus | 15 | 2.87e-01 | -0.159000 | 4.47e-01 |
| Adherens junctions interactions | 20 | 2.87e-01 | 0.137000 | 4.47e-01 |
| Syndecan interactions | 17 | 2.88e-01 | -0.149000 | 4.47e-01 |
| Signaling by KIT in disease | 19 | 2.88e-01 | -0.141000 | 4.47e-01 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | 19 | 2.88e-01 | -0.141000 | 4.47e-01 |
| Signaling by FGFR1 in disease | 30 | 2.89e-01 | -0.112000 | 4.48e-01 |
| Aquaporin-mediated transport | 28 | 2.94e-01 | 0.115000 | 4.55e-01 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | 38 | 2.96e-01 | 0.098100 | 4.57e-01 |
| Neurotransmitter release cycle | 31 | 2.97e-01 | -0.108000 | 4.58e-01 |
| Other semaphorin interactions | 10 | 2.98e-01 | -0.190000 | 4.60e-01 |
| Ion homeostasis | 35 | 3.00e-01 | -0.101000 | 4.62e-01 |
| TP53 Regulates Transcription of DNA Repair Genes | 61 | 3.01e-01 | -0.076600 | 4.63e-01 |
| NOD1/2 Signaling Pathway | 31 | 3.02e-01 | -0.107000 | 4.63e-01 |
| Sialic acid metabolism | 22 | 3.03e-01 | -0.127000 | 4.66e-01 |
| Mitochondrial translation elongation | 87 | 3.05e-01 | -0.063700 | 4.68e-01 |
| TNF signaling | 43 | 3.06e-01 | -0.090300 | 4.68e-01 |
| SUMO E3 ligases SUMOylate target proteins | 156 | 3.07e-01 | -0.047500 | 4.70e-01 |
| NCAM1 interactions | 18 | 3.08e-01 | 0.139000 | 4.70e-01 |
| Signaling by Hippo | 18 | 3.08e-01 | -0.139000 | 4.70e-01 |
| MET activates RAP1 and RAC1 | 10 | 3.08e-01 | -0.186000 | 4.70e-01 |
| Mitochondrial protein import | 61 | 3.10e-01 | -0.075300 | 4.72e-01 |
| Formation of the Early Elongation Complex | 33 | 3.10e-01 | -0.102000 | 4.72e-01 |
| Formation of the HIV-1 Early Elongation Complex | 33 | 3.10e-01 | -0.102000 | 4.72e-01 |
| GABA receptor activation | 29 | 3.12e-01 | 0.109000 | 4.73e-01 |
| TRAF3-dependent IRF activation pathway | 13 | 3.15e-01 | -0.161000 | 4.78e-01 |
| Role of phospholipids in phagocytosis | 17 | 3.17e-01 | -0.140000 | 4.81e-01 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | 13 | 3.18e-01 | 0.160000 | 4.82e-01 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | 71 | 3.19e-01 | -0.068500 | 4.82e-01 |
| tRNA modification in the nucleus and cytosol | 41 | 3.19e-01 | 0.089900 | 4.82e-01 |
| Signaling by Retinoic Acid | 33 | 3.20e-01 | 0.100000 | 4.83e-01 |
| Interleukin-10 signaling | 18 | 3.22e-01 | 0.135000 | 4.85e-01 |
| eNOS activation | 10 | 3.22e-01 | 0.181000 | 4.85e-01 |
| ADP signalling through P2Y purinoceptor 1 | 13 | 3.24e-01 | 0.158000 | 4.87e-01 |
| Trafficking of GluR2-containing AMPA receptors | 10 | 3.25e-01 | -0.180000 | 4.88e-01 |
| Vasopressin regulates renal water homeostasis via Aquaporins | 24 | 3.25e-01 | 0.116000 | 4.88e-01 |
| Signaling by Leptin | 10 | 3.26e-01 | 0.179000 | 4.88e-01 |
| Negative epigenetic regulation of rRNA expression | 47 | 3.27e-01 | -0.082700 | 4.89e-01 |
| Synaptic adhesion-like molecules | 14 | 3.27e-01 | 0.151000 | 4.89e-01 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | 35 | 3.28e-01 | -0.095600 | 4.89e-01 |
| Collagen formation | 53 | 3.28e-01 | 0.077700 | 4.89e-01 |
| Metabolism of cofactors | 18 | 3.30e-01 | 0.133000 | 4.92e-01 |
| RAS processing | 17 | 3.37e-01 | -0.135000 | 5.01e-01 |
| Deadenylation-dependent mRNA decay | 55 | 3.40e-01 | -0.074400 | 5.06e-01 |
| Mitotic G2-G2/M phases | 177 | 3.41e-01 | 0.041600 | 5.06e-01 |
| RA biosynthesis pathway | 15 | 3.41e-01 | 0.142000 | 5.07e-01 |
| Translesion Synthesis by POLH | 18 | 3.45e-01 | 0.129000 | 5.11e-01 |
| Purine catabolism | 14 | 3.49e-01 | 0.145000 | 5.16e-01 |
| Synthesis of IP2, IP, and Ins in the cytosol | 12 | 3.50e-01 | 0.156000 | 5.18e-01 |
| NoRC negatively regulates rRNA expression | 44 | 3.54e-01 | -0.080900 | 5.21e-01 |
| G beta:gamma signalling through CDC42 | 11 | 3.54e-01 | 0.161000 | 5.21e-01 |
| Signaling by BRAF and RAF1 fusions | 55 | 3.54e-01 | -0.072300 | 5.21e-01 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | 11 | 3.54e-01 | -0.161000 | 5.21e-01 |
| Interleukin-7 signaling | 16 | 3.54e-01 | 0.134000 | 5.21e-01 |
| Downstream signaling of activated FGFR1 | 20 | 3.55e-01 | -0.119000 | 5.21e-01 |
| mRNA Splicing - Minor Pathway | 52 | 3.55e-01 | -0.074200 | 5.21e-01 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | 69 | 3.57e-01 | -0.064200 | 5.23e-01 |
| Sensory processing of sound | 43 | 3.58e-01 | -0.081000 | 5.25e-01 |
| SHC-mediated cascade:FGFR2 | 10 | 3.59e-01 | -0.167000 | 5.26e-01 |
| Signaling by FGFR in disease | 49 | 3.62e-01 | -0.075400 | 5.29e-01 |
| Growth hormone receptor signaling | 20 | 3.67e-01 | 0.116000 | 5.37e-01 |
| DNA Damage Recognition in GG-NER | 38 | 3.69e-01 | -0.084300 | 5.37e-01 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | 19 | 3.69e-01 | -0.119000 | 5.37e-01 |
| Protein ubiquitination | 64 | 3.69e-01 | -0.064900 | 5.37e-01 |
| Synthesis of PIPs at the Golgi membrane | 15 | 3.70e-01 | -0.134000 | 5.38e-01 |
| Interleukin-4 and Interleukin-13 signaling | 66 | 3.74e-01 | -0.063400 | 5.43e-01 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | 50 | 3.75e-01 | -0.072600 | 5.44e-01 |
| Signaling by RAF1 mutants | 34 | 3.82e-01 | -0.086700 | 5.53e-01 |
| Assembly and cell surface presentation of NMDA receptors | 17 | 3.82e-01 | 0.122000 | 5.53e-01 |
| FGFR1 mutant receptor activation | 23 | 3.83e-01 | -0.105000 | 5.54e-01 |
| MET activates PTK2 signaling | 16 | 3.85e-01 | -0.125000 | 5.56e-01 |
| Sema3A PAK dependent Axon repulsion | 14 | 3.86e-01 | -0.134000 | 5.57e-01 |
| Molecules associated with elastic fibres | 19 | 3.88e-01 | 0.114000 | 5.57e-01 |
| Norepinephrine Neurotransmitter Release Cycle | 11 | 3.89e-01 | -0.150000 | 5.57e-01 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | 18 | 3.89e-01 | -0.117000 | 5.57e-01 |
| Regulation of TP53 Degradation | 34 | 3.90e-01 | -0.085300 | 5.57e-01 |
| Regulation of TP53 Expression and Degradation | 34 | 3.90e-01 | -0.085300 | 5.57e-01 |
| Intrinsic Pathway for Apoptosis | 50 | 3.90e-01 | -0.070400 | 5.57e-01 |
| Termination of O-glycan biosynthesis | 10 | 3.90e-01 | -0.157000 | 5.57e-01 |
| SUMOylation of DNA methylation proteins | 16 | 3.90e-01 | 0.124000 | 5.57e-01 |
| NOTCH3 Intracellular Domain Regulates Transcription | 17 | 3.91e-01 | -0.120000 | 5.57e-01 |
| Cell-cell junction organization | 42 | 3.91e-01 | 0.076600 | 5.57e-01 |
| Mucopolysaccharidoses | 11 | 3.91e-01 | -0.149000 | 5.57e-01 |
| Pyruvate metabolism and Citric Acid (TCA) cycle | 47 | 3.93e-01 | 0.072100 | 5.60e-01 |
| Xenobiotics | 15 | 3.94e-01 | 0.127000 | 5.61e-01 |
| Heme degradation | 14 | 3.98e-01 | 0.130000 | 5.67e-01 |
| Regulation of APC/C activators between G1/S and early anaphase | 77 | 3.99e-01 | -0.055700 | 5.67e-01 |
| Signaling by SCF-KIT | 37 | 4.01e-01 | -0.079800 | 5.69e-01 |
| TP53 Regulates Transcription of Death Receptors and Ligands | 11 | 4.02e-01 | -0.146000 | 5.70e-01 |
| Regulation of RUNX1 Expression and Activity | 17 | 4.04e-01 | -0.117000 | 5.72e-01 |
| Downregulation of ERBB2 signaling | 21 | 4.07e-01 | -0.105000 | 5.76e-01 |
| G2/M Transition | 175 | 4.09e-01 | 0.036300 | 5.78e-01 |
| Metabolism of fat-soluble vitamins | 39 | 4.09e-01 | 0.076400 | 5.78e-01 |
| Transcriptional Regulation by MECP2 | 45 | 4.10e-01 | -0.071100 | 5.78e-01 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | 17 | 4.10e-01 | -0.115000 | 5.78e-01 |
| HCMV Infection | 82 | 4.11e-01 | -0.052600 | 5.78e-01 |
| Synthesis of PIPs at the late endosome membrane | 10 | 4.13e-01 | -0.149000 | 5.81e-01 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | 31 | 4.16e-01 | -0.084400 | 5.85e-01 |
| NS1 Mediated Effects on Host Pathways | 39 | 4.17e-01 | -0.075200 | 5.85e-01 |
| Metabolism of steroid hormones | 23 | 4.17e-01 | 0.097800 | 5.85e-01 |
| Regulation of PTEN mRNA translation | 12 | 4.17e-01 | -0.135000 | 5.85e-01 |
| Pyroptosis | 20 | 4.18e-01 | 0.105000 | 5.85e-01 |
| Telomere Extension By Telomerase | 22 | 4.20e-01 | 0.099200 | 5.88e-01 |
| Early Phase of HIV Life Cycle | 12 | 4.29e-01 | 0.132000 | 5.98e-01 |
| CRMPs in Sema3A signaling | 12 | 4.31e-01 | -0.131000 | 6.02e-01 |
| Activation of kainate receptors upon glutamate binding | 16 | 4.33e-01 | 0.113000 | 6.03e-01 |
| Anti-inflammatory response favouring Leishmania parasite infection | 63 | 4.35e-01 | -0.057000 | 6.05e-01 |
| Leishmania parasite growth and survival | 63 | 4.35e-01 | -0.057000 | 6.05e-01 |
| Signaling by NTRK3 (TRKC) | 14 | 4.36e-01 | -0.120000 | 6.05e-01 |
| Nuclear Envelope Breakdown | 51 | 4.36e-01 | 0.063100 | 6.05e-01 |
| Synthesis of very long-chain fatty acyl-CoAs | 18 | 4.37e-01 | 0.106000 | 6.07e-01 |
| Zinc transporters | 15 | 4.39e-01 | -0.115000 | 6.08e-01 |
| DNA Damage/Telomere Stress Induced Senescence | 28 | 4.39e-01 | 0.084500 | 6.08e-01 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | 25 | 4.40e-01 | 0.089300 | 6.08e-01 |
| mRNA decay by 3’ to 5’ exoribonuclease | 16 | 4.40e-01 | 0.111000 | 6.08e-01 |
| Transcription of E2F targets under negative control by DREAM complex | 19 | 4.44e-01 | 0.102000 | 6.11e-01 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | 70 | 4.44e-01 | -0.053000 | 6.11e-01 |
| Sensory processing of sound by inner hair cells of the cochlea | 39 | 4.44e-01 | -0.070900 | 6.11e-01 |
| Signaling by FGFR2 in disease | 30 | 4.46e-01 | -0.080400 | 6.13e-01 |
| Metabolism of non-coding RNA | 52 | 4.46e-01 | 0.061100 | 6.13e-01 |
| snRNP Assembly | 52 | 4.46e-01 | 0.061100 | 6.13e-01 |
| Nuclear signaling by ERBB4 | 21 | 4.49e-01 | -0.095600 | 6.15e-01 |
| Bile acid and bile salt metabolism | 38 | 4.50e-01 | -0.070900 | 6.16e-01 |
| PKA activation | 12 | 4.51e-01 | 0.126000 | 6.17e-01 |
| Plasma lipoprotein assembly, remodeling, and clearance | 64 | 4.51e-01 | -0.054500 | 6.17e-01 |
| Signaling by NTRK2 (TRKB) | 20 | 4.54e-01 | -0.096700 | 6.20e-01 |
| TP53 Regulates Transcription of Cell Death Genes | 41 | 4.54e-01 | -0.067500 | 6.20e-01 |
| Pregnenolone biosynthesis | 10 | 4.57e-01 | 0.136000 | 6.23e-01 |
| Mitochondrial translation initiation | 87 | 4.58e-01 | -0.046100 | 6.24e-01 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | 22 | 4.59e-01 | -0.091300 | 6.24e-01 |
| Oxidative Stress Induced Senescence | 63 | 4.59e-01 | -0.053900 | 6.24e-01 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | 13 | 4.60e-01 | 0.118000 | 6.25e-01 |
| Listeria monocytogenes entry into host cells | 18 | 4.63e-01 | -0.099900 | 6.28e-01 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | 15 | 4.64e-01 | 0.109000 | 6.28e-01 |
| Purine salvage | 11 | 4.67e-01 | 0.127000 | 6.31e-01 |
| Inactivation, recovery and regulation of the phototransduction cascade | 20 | 4.67e-01 | -0.094000 | 6.31e-01 |
| Mitotic Telophase/Cytokinesis | 13 | 4.69e-01 | 0.116000 | 6.34e-01 |
| Mitotic G1 phase and G1/S transition | 144 | 4.70e-01 | 0.034900 | 6.35e-01 |
| ECM proteoglycans | 32 | 4.73e-01 | 0.073400 | 6.38e-01 |
| Regulation of lipid metabolism by PPARalpha | 115 | 4.78e-01 | -0.038400 | 6.44e-01 |
| Muscle contraction | 106 | 4.79e-01 | -0.039800 | 6.45e-01 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | 12 | 4.82e-01 | -0.117000 | 6.48e-01 |
| Long-term potentiation | 12 | 4.83e-01 | 0.117000 | 6.48e-01 |
| Nucleotide Excision Repair | 110 | 4.83e-01 | 0.038700 | 6.48e-01 |
| PI-3K cascade:FGFR2 | 10 | 4.84e-01 | -0.128000 | 6.48e-01 |
| Translesion synthesis by POLI | 17 | 4.87e-01 | 0.097400 | 6.52e-01 |
| PIWI-interacting RNA (piRNA) biogenesis | 18 | 4.87e-01 | -0.094600 | 6.52e-01 |
| Triglyceride biosynthesis | 10 | 4.87e-01 | 0.127000 | 6.52e-01 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | 32 | 4.91e-01 | -0.070400 | 6.55e-01 |
| Regulation of KIT signaling | 15 | 4.91e-01 | -0.103000 | 6.55e-01 |
| Establishment of Sister Chromatid Cohesion | 11 | 4.92e-01 | 0.120000 | 6.55e-01 |
| COPI-independent Golgi-to-ER retrograde traffic | 31 | 4.92e-01 | -0.071300 | 6.55e-01 |
| Activation of GABAB receptors | 23 | 4.93e-01 | 0.082700 | 6.55e-01 |
| GABA B receptor activation | 23 | 4.93e-01 | 0.082700 | 6.55e-01 |
| SUMOylation of DNA damage response and repair proteins | 76 | 4.95e-01 | 0.045300 | 6.56e-01 |
| G-protein mediated events | 37 | 4.95e-01 | -0.064800 | 6.56e-01 |
| Neuronal System | 207 | 4.96e-01 | 0.027500 | 6.56e-01 |
| Degradation of the extracellular matrix | 61 | 4.96e-01 | -0.050400 | 6.56e-01 |
| PKA activation in glucagon signalling | 11 | 4.96e-01 | 0.119000 | 6.56e-01 |
| Metabolism of porphyrins | 25 | 4.97e-01 | 0.078500 | 6.56e-01 |
| Generic Transcription Pathway | 1024 | 4.97e-01 | 0.012700 | 6.56e-01 |
| PKA-mediated phosphorylation of CREB | 14 | 4.98e-01 | 0.105000 | 6.57e-01 |
| Inwardly rectifying K+ channels | 17 | 5.01e-01 | 0.094300 | 6.60e-01 |
| EPHA-mediated growth cone collapse | 15 | 5.03e-01 | -0.099900 | 6.61e-01 |
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | 12 | 5.03e-01 | 0.112000 | 6.61e-01 |
| PPARA activates gene expression | 113 | 5.03e-01 | -0.036500 | 6.61e-01 |
| G alpha (12/13) signalling events | 59 | 5.05e-01 | -0.050200 | 6.63e-01 |
| ISG15 antiviral mechanism | 72 | 5.09e-01 | -0.045100 | 6.67e-01 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer’s disease models | 20 | 5.10e-01 | -0.085200 | 6.67e-01 |
| Neurodegenerative Diseases | 20 | 5.10e-01 | -0.085200 | 6.67e-01 |
| Diseases of metabolism | 179 | 5.10e-01 | 0.028600 | 6.67e-01 |
| Platelet sensitization by LDL | 15 | 5.12e-01 | -0.097900 | 6.69e-01 |
| Glycogen storage diseases | 13 | 5.13e-01 | 0.105000 | 6.69e-01 |
| Keratan sulfate biosynthesis | 20 | 5.14e-01 | -0.084200 | 6.71e-01 |
| Condensation of Prophase Chromosomes | 14 | 5.20e-01 | 0.099400 | 6.77e-01 |
| G-protein activation | 11 | 5.21e-01 | 0.112000 | 6.78e-01 |
| IRAK2 mediated activation of TAK1 complex | 10 | 5.21e-01 | -0.117000 | 6.78e-01 |
| Senescence-Associated Secretory Phenotype (SASP) | 49 | 5.26e-01 | 0.052400 | 6.83e-01 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | 18 | 5.26e-01 | 0.086300 | 6.83e-01 |
| KSRP (KHSRP) binds and destabilizes mRNA | 17 | 5.27e-01 | -0.088600 | 6.84e-01 |
| CaM pathway | 24 | 5.30e-01 | 0.074000 | 6.86e-01 |
| Calmodulin induced events | 24 | 5.30e-01 | 0.074000 | 6.86e-01 |
| RNA Polymerase I Transcription Initiation | 44 | 5.31e-01 | -0.054700 | 6.86e-01 |
| Glutamate Neurotransmitter Release Cycle | 17 | 5.32e-01 | -0.087500 | 6.88e-01 |
| HCMV Early Events | 58 | 5.36e-01 | -0.047100 | 6.90e-01 |
| Integrin signaling | 21 | 5.36e-01 | -0.078000 | 6.90e-01 |
| RHO GTPases Activate NADPH Oxidases | 16 | 5.36e-01 | -0.089400 | 6.90e-01 |
| Meiotic synapsis | 26 | 5.36e-01 | 0.070100 | 6.90e-01 |
| Pentose phosphate pathway | 13 | 5.37e-01 | 0.098900 | 6.90e-01 |
| Stimuli-sensing channels | 59 | 5.38e-01 | -0.046400 | 6.91e-01 |
| STING mediated induction of host immune responses | 10 | 5.38e-01 | -0.112000 | 6.91e-01 |
| Activation of G protein gated Potassium channels | 14 | 5.42e-01 | 0.094200 | 6.93e-01 |
| G protein gated Potassium channels | 14 | 5.42e-01 | 0.094200 | 6.93e-01 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | 14 | 5.42e-01 | 0.094200 | 6.93e-01 |
| G alpha (s) signalling events | 50 | 5.43e-01 | -0.049700 | 6.94e-01 |
| Signaling by BMP | 16 | 5.43e-01 | 0.087800 | 6.94e-01 |
| Maturation of nucleoprotein | 11 | 5.45e-01 | 0.105000 | 6.95e-01 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | 72 | 5.46e-01 | -0.041200 | 6.96e-01 |
| Postmitotic nuclear pore complex (NPC) reformation | 27 | 5.47e-01 | -0.067000 | 6.96e-01 |
| BMAL1:CLOCK,NPAS2 activates circadian gene expression | 25 | 5.48e-01 | -0.069500 | 6.97e-01 |
| Synthesis of PC | 24 | 5.48e-01 | -0.070900 | 6.97e-01 |
| Interleukin-6 family signaling | 19 | 5.50e-01 | -0.079300 | 6.98e-01 |
| Glutamate and glutamine metabolism | 11 | 5.50e-01 | 0.104000 | 6.98e-01 |
| RND3 GTPase cycle | 36 | 5.51e-01 | -0.057500 | 6.98e-01 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | 30 | 5.52e-01 | 0.062700 | 6.99e-01 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | 30 | 5.52e-01 | 0.062700 | 6.99e-01 |
| Hyaluronan uptake and degradation | 10 | 5.55e-01 | -0.108000 | 7.02e-01 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | 14 | 5.56e-01 | -0.091000 | 7.02e-01 |
| Prefoldin mediated transfer of substrate to CCT/TriC | 25 | 5.58e-01 | -0.067700 | 7.04e-01 |
| Mitochondrial calcium ion transport | 21 | 5.59e-01 | -0.073600 | 7.05e-01 |
| Regulation of FZD by ubiquitination | 15 | 5.59e-01 | -0.087100 | 7.05e-01 |
| Defective Intrinsic Pathway for Apoptosis | 23 | 5.60e-01 | -0.070200 | 7.05e-01 |
| Signaling by CSF3 (G-CSF) | 27 | 5.63e-01 | -0.064400 | 7.08e-01 |
| Diseases associated with O-glycosylation of proteins | 36 | 5.66e-01 | 0.055200 | 7.11e-01 |
| Regulation of IFNG signaling | 13 | 5.67e-01 | 0.091800 | 7.11e-01 |
| Signaling by Activin | 12 | 5.70e-01 | -0.094800 | 7.14e-01 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | 13 | 5.70e-01 | -0.091000 | 7.14e-01 |
| RHO GTPase Effectors | 222 | 5.72e-01 | 0.022100 | 7.16e-01 |
| RHO GTPases activate IQGAPs | 11 | 5.74e-01 | -0.097800 | 7.18e-01 |
| Josephin domain DUBs | 10 | 5.75e-01 | -0.102000 | 7.18e-01 |
| Interleukin-37 signaling | 15 | 5.75e-01 | -0.083700 | 7.18e-01 |
| Interleukin-6 signaling | 10 | 5.76e-01 | -0.102000 | 7.18e-01 |
| Activation of the AP-1 family of transcription factors | 10 | 5.78e-01 | -0.102000 | 7.19e-01 |
| Class B/2 (Secretin family receptors) | 39 | 5.78e-01 | 0.051600 | 7.19e-01 |
| Platelet Aggregation (Plug Formation) | 24 | 5.78e-01 | -0.065600 | 7.19e-01 |
| FRS-mediated FGFR2 signaling | 12 | 5.80e-01 | -0.092200 | 7.21e-01 |
| SUMOylation of chromatin organization proteins | 55 | 5.86e-01 | 0.042400 | 7.28e-01 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | 28 | 5.87e-01 | -0.059300 | 7.28e-01 |
| Non-integrin membrane-ECM interactions | 37 | 5.88e-01 | -0.051500 | 7.28e-01 |
| Translesion synthesis by POLK | 17 | 5.90e-01 | 0.075500 | 7.31e-01 |
| Rap1 signalling | 11 | 5.91e-01 | -0.093600 | 7.31e-01 |
| SLBP independent Processing of Histone Pre-mRNAs | 10 | 5.94e-01 | 0.097500 | 7.34e-01 |
| RHO GTPases activate PKNs | 31 | 5.94e-01 | -0.055300 | 7.34e-01 |
| Interleukin-2 family signaling | 29 | 5.97e-01 | -0.056800 | 7.36e-01 |
| Regulation of beta-cell development | 27 | 5.97e-01 | 0.058800 | 7.36e-01 |
| DNA Damage Bypass | 47 | 6.00e-01 | 0.044300 | 7.39e-01 |
| TP53 Regulates Transcription of Cell Cycle Genes | 47 | 6.03e-01 | 0.043900 | 7.41e-01 |
| Phase 0 - rapid depolarisation | 17 | 6.04e-01 | 0.072600 | 7.43e-01 |
| Branched-chain amino acid catabolism | 21 | 6.05e-01 | 0.065200 | 7.43e-01 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | 26 | 6.07e-01 | -0.058300 | 7.45e-01 |
| Respiratory electron transport | 103 | 6.08e-01 | -0.029300 | 7.45e-01 |
| Sema4D induced cell migration and growth-cone collapse | 20 | 6.09e-01 | -0.066000 | 7.45e-01 |
| SUMOylation of RNA binding proteins | 46 | 6.09e-01 | 0.043600 | 7.45e-01 |
| Metabolism of lipids | 592 | 6.09e-01 | 0.012400 | 7.45e-01 |
| Glycogen synthesis | 14 | 6.12e-01 | -0.078300 | 7.48e-01 |
| VxPx cargo-targeting to cilium | 18 | 6.12e-01 | -0.069000 | 7.48e-01 |
| Post-translational protein phosphorylation | 91 | 6.14e-01 | -0.030600 | 7.49e-01 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | 20 | 6.15e-01 | -0.064900 | 7.49e-01 |
| Formation of apoptosome | 11 | 6.16e-01 | -0.087400 | 7.49e-01 |
| Regulation of the apoptosome activity | 11 | 6.16e-01 | -0.087400 | 7.49e-01 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | 11 | 6.18e-01 | -0.086900 | 7.51e-01 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | 16 | 6.21e-01 | 0.071400 | 7.53e-01 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | 16 | 6.21e-01 | 0.071400 | 7.53e-01 |
| Signaling by NOTCH2 | 24 | 6.26e-01 | -0.057500 | 7.56e-01 |
| Metal ion SLC transporters | 23 | 6.26e-01 | -0.058700 | 7.56e-01 |
| Signaling by ALK | 20 | 6.26e-01 | -0.062900 | 7.56e-01 |
| RIPK1-mediated regulated necrosis | 27 | 6.26e-01 | -0.054100 | 7.56e-01 |
| Regulation of necroptotic cell death | 27 | 6.26e-01 | -0.054100 | 7.56e-01 |
| RUNX2 regulates osteoblast differentiation | 16 | 6.27e-01 | 0.070300 | 7.56e-01 |
| Gamma carboxylation, hypusine formation and arylsulfatase activation | 37 | 6.27e-01 | 0.046100 | 7.56e-01 |
| Triglyceride catabolism | 12 | 6.28e-01 | -0.080700 | 7.56e-01 |
| Potassium Channels | 37 | 6.28e-01 | 0.046000 | 7.56e-01 |
| Alpha-protein kinase 1 signaling pathway | 11 | 6.29e-01 | 0.084000 | 7.56e-01 |
| Cytochrome c-mediated apoptotic response | 13 | 6.29e-01 | -0.077300 | 7.56e-01 |
| Metabolism of carbohydrates | 235 | 6.32e-01 | 0.018200 | 7.59e-01 |
| Peptide ligand-binding receptors | 51 | 6.35e-01 | 0.038500 | 7.61e-01 |
| Laminin interactions | 21 | 6.36e-01 | 0.059600 | 7.62e-01 |
| DCC mediated attractive signaling | 12 | 6.38e-01 | -0.078500 | 7.63e-01 |
| Formation of the cornified envelope | 21 | 6.38e-01 | -0.059300 | 7.63e-01 |
| Nef mediated downregulation of MHC class I complex cell surface expression | 10 | 6.41e-01 | 0.085100 | 7.66e-01 |
| Prolactin receptor signaling | 11 | 6.42e-01 | -0.081000 | 7.66e-01 |
| Class I peroxisomal membrane protein import | 19 | 6.42e-01 | 0.061600 | 7.66e-01 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | 73 | 6.44e-01 | -0.031300 | 7.68e-01 |
| Activation of SMO | 14 | 6.46e-01 | -0.071000 | 7.69e-01 |
| Nuclear import of Rev protein | 33 | 6.46e-01 | -0.046200 | 7.69e-01 |
| Unblocking of NMDA receptors, glutamate binding and activation | 11 | 6.48e-01 | 0.079500 | 7.71e-01 |
| E3 ubiquitin ligases ubiquitinate target proteins | 44 | 6.52e-01 | -0.039400 | 7.73e-01 |
| Regulation of FOXO transcriptional activity by acetylation | 10 | 6.52e-01 | -0.082400 | 7.73e-01 |
| Cohesin Loading onto Chromatin | 10 | 6.52e-01 | -0.082400 | 7.73e-01 |
| Interaction between L1 and Ankyrins | 15 | 6.53e-01 | -0.067000 | 7.74e-01 |
| Signaling by NODAL | 15 | 6.54e-01 | 0.066900 | 7.74e-01 |
| Pyruvate metabolism | 24 | 6.55e-01 | 0.052600 | 7.74e-01 |
| RNA Pol II CTD phosphorylation and interaction with CE | 27 | 6.55e-01 | -0.049600 | 7.74e-01 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | 27 | 6.55e-01 | -0.049600 | 7.74e-01 |
| The phototransduction cascade | 21 | 6.56e-01 | -0.056100 | 7.74e-01 |
| Activation of Matrix Metalloproteinases | 15 | 6.57e-01 | 0.066100 | 7.75e-01 |
| Glycogen breakdown (glycogenolysis) | 15 | 6.58e-01 | 0.066100 | 7.75e-01 |
| Citric acid cycle (TCA cycle) | 21 | 6.59e-01 | 0.055700 | 7.75e-01 |
| Inhibition of DNA recombination at telomere | 21 | 6.62e-01 | 0.055100 | 7.78e-01 |
| Cytosolic iron-sulfur cluster assembly | 11 | 6.62e-01 | 0.076100 | 7.78e-01 |
| tRNA processing in the nucleus | 54 | 6.66e-01 | -0.033900 | 7.82e-01 |
| Neurotransmitter receptors and postsynaptic signal transmission | 108 | 6.69e-01 | 0.023800 | 7.84e-01 |
| PLC beta mediated events | 33 | 6.70e-01 | -0.042900 | 7.84e-01 |
| Caspase activation via extrinsic apoptotic signalling pathway | 21 | 6.70e-01 | -0.053800 | 7.84e-01 |
| Fertilization | 10 | 6.71e-01 | -0.077700 | 7.85e-01 |
| Notch-HLH transcription pathway | 24 | 6.71e-01 | -0.050000 | 7.85e-01 |
| Interferon gamma signaling | 57 | 6.79e-01 | 0.031700 | 7.93e-01 |
| Chemokine receptors bind chemokines | 13 | 6.83e-01 | -0.065500 | 7.96e-01 |
| Recognition of DNA damage by PCNA-containing replication complex | 30 | 6.83e-01 | 0.043100 | 7.96e-01 |
| Ca2+ pathway | 44 | 6.86e-01 | 0.035300 | 7.99e-01 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | 10 | 6.87e-01 | -0.073700 | 7.99e-01 |
| Signal amplification | 19 | 6.87e-01 | -0.053300 | 8.00e-01 |
| Purine ribonucleoside monophosphate biosynthesis | 11 | 6.90e-01 | 0.069400 | 8.02e-01 |
| Amyloid fiber formation | 41 | 6.91e-01 | 0.035900 | 8.02e-01 |
| Dopamine Neurotransmitter Release Cycle | 14 | 6.96e-01 | 0.060400 | 8.06e-01 |
| G beta:gamma signalling through PLC beta | 11 | 6.96e-01 | 0.068000 | 8.06e-01 |
| Presynaptic function of Kainate receptors | 11 | 6.96e-01 | 0.068000 | 8.06e-01 |
| Initiation of Nuclear Envelope (NE) Reformation | 19 | 6.98e-01 | -0.051500 | 8.07e-01 |
| NCAM signaling for neurite out-growth | 35 | 7.02e-01 | 0.037400 | 8.11e-01 |
| G alpha (z) signalling events | 25 | 7.08e-01 | -0.043300 | 8.18e-01 |
| DNA Double Strand Break Response | 40 | 7.09e-01 | -0.034100 | 8.18e-01 |
| Translesion synthesis by REV1 | 16 | 7.12e-01 | 0.053300 | 8.21e-01 |
| Ca-dependent events | 25 | 7.14e-01 | 0.042400 | 8.22e-01 |
| The NLRP3 inflammasome | 14 | 7.14e-01 | 0.056600 | 8.22e-01 |
| G-protein beta:gamma signalling | 17 | 7.18e-01 | -0.050500 | 8.26e-01 |
| RNA Polymerase I Transcription Termination | 27 | 7.26e-01 | -0.039000 | 8.34e-01 |
| G alpha (i) signalling events | 121 | 7.26e-01 | -0.018500 | 8.34e-01 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | 78 | 7.28e-01 | -0.022800 | 8.34e-01 |
| mRNA decay by 5’ to 3’ exoribonuclease | 15 | 7.28e-01 | -0.051900 | 8.34e-01 |
| RNA Polymerase I Promoter Clearance | 48 | 7.32e-01 | -0.028600 | 8.37e-01 |
| RNA Polymerase I Transcription | 48 | 7.32e-01 | -0.028600 | 8.37e-01 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | 13 | 7.32e-01 | -0.054800 | 8.37e-01 |
| Transcriptional Regulation by E2F6 | 34 | 7.33e-01 | 0.033900 | 8.37e-01 |
| SUMOylation of ubiquitinylation proteins | 38 | 7.35e-01 | -0.031800 | 8.38e-01 |
| Interactions of Rev with host cellular proteins | 36 | 7.35e-01 | -0.032600 | 8.38e-01 |
| Metalloprotease DUBs | 16 | 7.35e-01 | 0.048800 | 8.38e-01 |
| Gene Silencing by RNA | 68 | 7.36e-01 | -0.023700 | 8.38e-01 |
| Tryptophan catabolism | 10 | 7.43e-01 | 0.059900 | 8.45e-01 |
| Downregulation of ERBB2:ERBB3 signaling | 10 | 7.46e-01 | -0.059100 | 8.47e-01 |
| TNFR1-induced NFkappaB signaling pathway | 25 | 7.46e-01 | -0.037400 | 8.47e-01 |
| Processing of SMDT1 | 15 | 7.47e-01 | -0.048200 | 8.47e-01 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | 11 | 7.49e-01 | 0.055800 | 8.49e-01 |
| Negative regulators of DDX58/IFIH1 signaling | 35 | 7.50e-01 | -0.031200 | 8.50e-01 |
| Protein folding | 78 | 7.53e-01 | 0.020600 | 8.52e-01 |
| O-linked glycosylation | 64 | 7.53e-01 | 0.022700 | 8.52e-01 |
| Gluconeogenesis | 27 | 7.54e-01 | 0.034800 | 8.53e-01 |
| Response to elevated platelet cytosolic Ca2+ | 106 | 7.57e-01 | 0.017400 | 8.55e-01 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | 27 | 7.58e-01 | -0.034200 | 8.55e-01 |
| IL-6-type cytokine receptor ligand interactions | 13 | 7.58e-01 | -0.049300 | 8.55e-01 |
| Cargo trafficking to the periciliary membrane | 47 | 7.61e-01 | 0.025700 | 8.56e-01 |
| Aflatoxin activation and detoxification | 15 | 7.61e-01 | 0.045400 | 8.56e-01 |
| ADORA2B mediated anti-inflammatory cytokines production | 42 | 7.61e-01 | 0.027100 | 8.56e-01 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | 24 | 7.62e-01 | -0.035800 | 8.56e-01 |
| G1/S Transition | 127 | 7.65e-01 | 0.015400 | 8.59e-01 |
| Regulation of localization of FOXO transcription factors | 10 | 7.66e-01 | -0.054200 | 8.59e-01 |
| Diseases of glycosylation | 99 | 7.67e-01 | 0.017300 | 8.59e-01 |
| Detoxification of Reactive Oxygen Species | 28 | 7.67e-01 | -0.032300 | 8.59e-01 |
| Glucuronidation | 10 | 7.68e-01 | -0.054000 | 8.59e-01 |
| Platelet homeostasis | 48 | 7.69e-01 | -0.024500 | 8.60e-01 |
| Transport of Ribonucleoproteins into the Host Nucleus | 31 | 7.69e-01 | -0.030400 | 8.60e-01 |
| Caspase-mediated cleavage of cytoskeletal proteins | 11 | 7.71e-01 | 0.050800 | 8.61e-01 |
| Glycosaminoglycan metabolism | 90 | 7.71e-01 | -0.017700 | 8.61e-01 |
| Gene expression (Transcription) | 1265 | 7.76e-01 | -0.004840 | 8.65e-01 |
| Complex I biogenesis | 57 | 7.76e-01 | 0.021800 | 8.65e-01 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | 10 | 7.77e-01 | -0.051700 | 8.65e-01 |
| The citric acid (TCA) cycle and respiratory electron transport | 151 | 7.81e-01 | 0.013200 | 8.67e-01 |
| Blood group systems biosynthesis | 13 | 7.81e-01 | 0.044600 | 8.67e-01 |
| TNFR1-induced proapoptotic signaling | 12 | 7.82e-01 | 0.046200 | 8.67e-01 |
| Regulation of MECP2 expression and activity | 29 | 7.82e-01 | -0.029700 | 8.67e-01 |
| Regulation of pyruvate dehydrogenase (PDH) complex | 15 | 7.88e-01 | 0.040000 | 8.74e-01 |
| Surfactant metabolism | 14 | 7.89e-01 | 0.041200 | 8.74e-01 |
| G beta:gamma signalling through PI3Kgamma | 13 | 7.92e-01 | 0.042400 | 8.76e-01 |
| Depolymerisation of the Nuclear Lamina | 14 | 7.93e-01 | -0.040600 | 8.77e-01 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | 42 | 7.94e-01 | -0.023300 | 8.77e-01 |
| Nuclear Envelope (NE) Reassembly | 69 | 7.96e-01 | 0.018000 | 8.78e-01 |
| Regulation of innate immune responses to cytosolic DNA | 11 | 7.98e-01 | -0.044700 | 8.78e-01 |
| Interferon Signaling | 147 | 7.98e-01 | 0.012300 | 8.78e-01 |
| DAG and IP3 signaling | 30 | 7.98e-01 | 0.027000 | 8.78e-01 |
| RMTs methylate histone arginines | 30 | 7.98e-01 | 0.027000 | 8.78e-01 |
| Transport of the SLBP Dependant Mature mRNA | 35 | 7.99e-01 | -0.024900 | 8.78e-01 |
| Inactivation of CSF3 (G-CSF) signaling | 22 | 7.99e-01 | 0.031300 | 8.79e-01 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | 17 | 8.03e-01 | -0.034900 | 8.81e-01 |
| Signaling by PDGF | 44 | 8.04e-01 | 0.021700 | 8.81e-01 |
| Adrenaline,noradrenaline inhibits insulin secretion | 15 | 8.04e-01 | -0.037100 | 8.81e-01 |
| Interactions of Vpr with host cellular proteins | 36 | 8.04e-01 | -0.023900 | 8.81e-01 |
| Metabolism of nitric oxide: NOS3 activation and regulation | 13 | 8.07e-01 | -0.039200 | 8.82e-01 |
| Lewis blood group biosynthesis | 11 | 8.07e-01 | -0.042600 | 8.82e-01 |
| SLC transporter disorders | 70 | 8.08e-01 | -0.016800 | 8.83e-01 |
| mRNA Capping | 29 | 8.15e-01 | -0.025200 | 8.90e-01 |
| Recycling of bile acids and salts | 13 | 8.16e-01 | -0.037300 | 8.90e-01 |
| Glycogen metabolism | 25 | 8.20e-01 | -0.026200 | 8.94e-01 |
| NOTCH4 Intracellular Domain Regulates Transcription | 15 | 8.23e-01 | -0.033300 | 8.97e-01 |
| Protein localization | 150 | 8.28e-01 | -0.010300 | 9.01e-01 |
| Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | 108 | 8.29e-01 | -0.012000 | 9.01e-01 |
| Apoptotic factor-mediated response | 18 | 8.30e-01 | 0.029200 | 9.01e-01 |
| Ras activation upon Ca2+ influx through NMDA receptor | 16 | 8.30e-01 | -0.030900 | 9.01e-01 |
| Pre-NOTCH Transcription and Translation | 31 | 8.31e-01 | -0.022200 | 9.01e-01 |
| Activation of NMDA receptors and postsynaptic events | 56 | 8.31e-01 | 0.016500 | 9.01e-01 |
| Switching of origins to a post-replicative state | 87 | 8.32e-01 | -0.013200 | 9.01e-01 |
| Regulation of TP53 Activity | 152 | 8.32e-01 | -0.009970 | 9.01e-01 |
| Vpr-mediated nuclear import of PICs | 33 | 8.34e-01 | 0.021100 | 9.01e-01 |
| RNA Polymerase I Promoter Escape | 29 | 8.34e-01 | -0.022500 | 9.01e-01 |
| PECAM1 interactions | 11 | 8.37e-01 | 0.035800 | 9.04e-01 |
| Tight junction interactions | 21 | 8.38e-01 | 0.025800 | 9.04e-01 |
| Formation of tubulin folding intermediates by CCT/TriC | 20 | 8.39e-01 | -0.026200 | 9.05e-01 |
| ADP signalling through P2Y purinoceptor 12 | 12 | 8.41e-01 | 0.033400 | 9.06e-01 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | 39 | 8.42e-01 | -0.018400 | 9.07e-01 |
| Golgi Cisternae Pericentriolar Stack Reorganization | 14 | 8.46e-01 | -0.029900 | 9.10e-01 |
| FCGR3A-mediated IL10 synthesis | 23 | 8.50e-01 | 0.022800 | 9.13e-01 |
| Factors involved in megakaryocyte development and platelet production | 103 | 8.53e-01 | 0.010600 | 9.16e-01 |
| Platelet degranulation | 103 | 8.53e-01 | 0.010600 | 9.16e-01 |
| Nucleotide catabolism | 28 | 8.58e-01 | 0.019500 | 9.20e-01 |
| Processing of Capped Intronless Pre-mRNA | 28 | 8.59e-01 | -0.019400 | 9.20e-01 |
| MASTL Facilitates Mitotic Progression | 10 | 8.59e-01 | -0.032500 | 9.20e-01 |
| p130Cas linkage to MAPK signaling for integrins | 13 | 8.64e-01 | 0.027500 | 9.24e-01 |
| TNFs bind their physiological receptors | 11 | 8.72e-01 | -0.028100 | 9.32e-01 |
| Chylomicron assembly | 10 | 8.73e-01 | 0.029200 | 9.32e-01 |
| Regulated Necrosis | 47 | 8.73e-01 | 0.013400 | 9.32e-01 |
| Inflammasomes | 18 | 8.79e-01 | -0.020700 | 9.38e-01 |
| Processing and activation of SUMO | 10 | 8.80e-01 | 0.027500 | 9.38e-01 |
| DNA Replication Pre-Initiation | 85 | 8.82e-01 | -0.009310 | 9.39e-01 |
| Protein methylation | 15 | 8.83e-01 | 0.021900 | 9.40e-01 |
| BBSome-mediated cargo-targeting to cilium | 23 | 8.85e-01 | 0.017400 | 9.40e-01 |
| Diseases associated with glycosylation precursor biosynthesis | 18 | 8.86e-01 | -0.019600 | 9.40e-01 |
| Thrombin signalling through proteinase activated receptors (PARs) | 21 | 8.86e-01 | -0.018100 | 9.40e-01 |
| APC/C-mediated degradation of cell cycle proteins | 84 | 8.88e-01 | -0.008930 | 9.41e-01 |
| Regulation of mitotic cell cycle | 84 | 8.88e-01 | -0.008930 | 9.41e-01 |
| O-linked glycosylation of mucins | 34 | 8.88e-01 | 0.013900 | 9.41e-01 |
| Smooth Muscle Contraction | 28 | 8.90e-01 | -0.015100 | 9.42e-01 |
| Caspase activation via Death Receptors in the presence of ligand | 13 | 8.93e-01 | 0.021500 | 9.44e-01 |
| Transmission across Chemical Synapses | 146 | 8.94e-01 | -0.006410 | 9.44e-01 |
| Interleukin-15 signaling | 12 | 8.95e-01 | 0.022000 | 9.44e-01 |
| Killing mechanisms | 10 | 8.96e-01 | -0.023900 | 9.44e-01 |
| WNT5:FZD7-mediated leishmania damping | 10 | 8.96e-01 | -0.023900 | 9.44e-01 |
| HuR (ELAVL1) binds and stabilizes mRNA | 10 | 8.96e-01 | -0.023800 | 9.44e-01 |
| Cellular Senescence | 124 | 8.99e-01 | 0.006580 | 9.47e-01 |
| Thromboxane signalling through TP receptor | 14 | 9.00e-01 | -0.019400 | 9.47e-01 |
| Interconversion of nucleotide di- and triphosphates | 27 | 9.05e-01 | 0.013300 | 9.51e-01 |
| HCMV Late Events | 55 | 9.06e-01 | -0.009220 | 9.52e-01 |
| RUNX2 regulates bone development | 22 | 9.07e-01 | 0.014400 | 9.52e-01 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | 13 | 9.08e-01 | -0.018500 | 9.52e-01 |
| Triglyceride metabolism | 22 | 9.12e-01 | 0.013700 | 9.55e-01 |
| Signaling by FGFR2 IIIa TM | 17 | 9.16e-01 | 0.014800 | 9.59e-01 |
| Heme biosynthesis | 13 | 9.17e-01 | 0.016700 | 9.60e-01 |
| Viral Messenger RNA Synthesis | 43 | 9.18e-01 | -0.009050 | 9.60e-01 |
| Gap junction trafficking and regulation | 14 | 9.21e-01 | -0.015300 | 9.60e-01 |
| CASP8 activity is inhibited | 10 | 9.21e-01 | -0.018100 | 9.60e-01 |
| Dimerization of procaspase-8 | 10 | 9.21e-01 | -0.018100 | 9.60e-01 |
| Regulation by c-FLIP | 10 | 9.21e-01 | -0.018100 | 9.60e-01 |
| Cellular hexose transport | 16 | 9.26e-01 | -0.013500 | 9.63e-01 |
| NEP/NS2 Interacts with the Cellular Export Machinery | 31 | 9.28e-01 | -0.009340 | 9.63e-01 |
| Cyclin D associated events in G1 | 46 | 9.30e-01 | 0.007530 | 9.63e-01 |
| G1 Phase | 46 | 9.30e-01 | 0.007530 | 9.63e-01 |
| Regulation of TP53 Activity through Association with Co-factors | 11 | 9.33e-01 | -0.014700 | 9.63e-01 |
| TRP channels | 10 | 9.33e-01 | 0.015300 | 9.63e-01 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | 21 | 9.34e-01 | 0.010500 | 9.63e-01 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | 12 | 9.34e-01 | 0.013900 | 9.63e-01 |
| Dual incision in TC-NER | 65 | 9.34e-01 | -0.005910 | 9.63e-01 |
| HIV Transcription Initiation | 45 | 9.35e-01 | -0.007060 | 9.63e-01 |
| RNA Polymerase II HIV Promoter Escape | 45 | 9.35e-01 | -0.007060 | 9.63e-01 |
| RNA Polymerase II Promoter Escape | 45 | 9.35e-01 | -0.007060 | 9.63e-01 |
| RNA Polymerase II Transcription Initiation | 45 | 9.35e-01 | -0.007060 | 9.63e-01 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | 45 | 9.35e-01 | -0.007060 | 9.63e-01 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | 45 | 9.35e-01 | -0.007060 | 9.63e-01 |
| Post NMDA receptor activation events | 47 | 9.36e-01 | -0.006790 | 9.63e-01 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | 64 | 9.36e-01 | 0.005810 | 9.63e-01 |
| Glucose metabolism | 81 | 9.38e-01 | 0.004980 | 9.65e-01 |
| Plasma lipoprotein assembly | 17 | 9.42e-01 | 0.010300 | 9.68e-01 |
| RHO GTPases activate CIT | 19 | 9.45e-01 | 0.009130 | 9.70e-01 |
| Metabolism of folate and pterines | 16 | 9.46e-01 | -0.009830 | 9.70e-01 |
| SUMOylation of SUMOylation proteins | 34 | 9.46e-01 | 0.006730 | 9.70e-01 |
| Transcriptional regulation by small RNAs | 47 | 9.49e-01 | 0.005380 | 9.72e-01 |
| Assembly of the ORC complex at the origin of replication | 10 | 9.50e-01 | 0.011600 | 9.72e-01 |
| Voltage gated Potassium channels | 12 | 9.53e-01 | 0.009910 | 9.74e-01 |
| SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | 11 | 9.53e-01 | 0.010300 | 9.74e-01 |
| Defects in vitamin and cofactor metabolism | 20 | 9.54e-01 | -0.007500 | 9.74e-01 |
| Interleukin-27 signaling | 10 | 9.54e-01 | -0.010500 | 9.74e-01 |
| Sensory processing of sound by outer hair cells of the cochlea | 31 | 9.55e-01 | 0.005820 | 9.74e-01 |
| Glycerophospholipid biosynthesis | 90 | 9.58e-01 | 0.003240 | 9.76e-01 |
| Regulation of insulin secretion | 47 | 9.58e-01 | -0.004430 | 9.76e-01 |
| Serotonin Neurotransmitter Release Cycle | 10 | 9.59e-01 | 0.009340 | 9.76e-01 |
| Collagen degradation | 20 | 9.64e-01 | -0.005900 | 9.80e-01 |
| Integration of energy metabolism | 73 | 9.65e-01 | 0.002940 | 9.80e-01 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | 21 | 9.66e-01 | 0.005430 | 9.80e-01 |
| Trafficking of AMPA receptors | 21 | 9.66e-01 | 0.005430 | 9.80e-01 |
| Mitotic Prophase | 81 | 9.71e-01 | -0.002370 | 9.84e-01 |
| SUMOylation of transcription factors | 16 | 9.72e-01 | 0.005010 | 9.85e-01 |
| Synthesis of PE | 12 | 9.73e-01 | 0.005700 | 9.85e-01 |
| Gap junction trafficking | 12 | 9.74e-01 | -0.005450 | 9.85e-01 |
| Transport of Mature mRNA Derived from an Intronless Transcript | 41 | 9.75e-01 | -0.002860 | 9.85e-01 |
| Oncogene Induced Senescence | 33 | 9.79e-01 | 0.002600 | 9.89e-01 |
| Transcriptional regulation of pluripotent stem cells | 21 | 9.81e-01 | 0.003010 | 9.90e-01 |
| RNA Polymerase II Transcription | 1142 | 9.84e-01 | -0.000350 | 9.93e-01 |
| Processing of Intronless Pre-mRNAs | 19 | 9.85e-01 | -0.002490 | 9.93e-01 |
| Chondroitin sulfate/dermatan sulfate metabolism | 40 | 9.86e-01 | 0.001610 | 9.93e-01 |
| Export of Viral Ribonucleoproteins from Nucleus | 32 | 9.87e-01 | -0.001660 | 9.94e-01 |
| Diseases of carbohydrate metabolism | 29 | 9.88e-01 | -0.001650 | 9.94e-01 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | 99 | 9.90e-01 | 0.000729 | 9.95e-01 |
| Chaperonin-mediated protein folding | 72 | 9.91e-01 | 0.000811 | 9.95e-01 |
| Interleukin-35 Signalling | 10 | 9.91e-01 | -0.001970 | 9.95e-01 |
| Other interleukin signaling | 18 | 9.92e-01 | 0.001290 | 9.95e-01 |
| FGFR2 mutant receptor activation | 20 | 9.95e-01 | -0.000820 | 9.97e-01 |
| Rev-mediated nuclear export of HIV RNA | 34 | 9.95e-01 | 0.000584 | 9.97e-01 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | 24 | 9.97e-01 | 0.000465 | 9.98e-01 |
| Transport of the SLBP independent Mature mRNA | 34 | 9.98e-01 | -0.000288 | 9.98e-01 |
Detailed Gene set reports
Cellular responses to stimuli
| 155 | |
|---|---|
| set | Cellular responses to stimuli |
| setSize | 641 |
| pANOVA | 1.36e-21 |
| s.dist | -0.222 |
| p.adjustANOVA | 1.87e-18 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| HSPA5 | -7144 |
| CALR | -7142 |
| DNAJB11 | -7141 |
| HYOU1 | -7140 |
| HERPUD1 | -7137 |
| DNAJC3 | -7131 |
| HSP90B1 | -7129 |
| DNAJB9 | -7125 |
| SYVN1 | -7108 |
| PDIA6 | -7106 |
| EDEM1 | -7103 |
| WFS1 | -7096 |
| ATP6V0B | -7064 |
| CSRP1 | -7054 |
| GFPT1 | -7051 |
| DDIT3 | -7047 |
| EIF2AK3 | -7028 |
| HM13 | -7025 |
| FLCN | -7022 |
| RRAGC | -7009 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HSPA5 | -7144 |
| CALR | -7142 |
| DNAJB11 | -7141 |
| HYOU1 | -7140 |
| HERPUD1 | -7137 |
| DNAJC3 | -7131 |
| HSP90B1 | -7129 |
| DNAJB9 | -7125 |
| SYVN1 | -7108 |
| PDIA6 | -7106 |
| EDEM1 | -7103 |
| WFS1 | -7096 |
| ATP6V0B | -7064 |
| CSRP1 | -7054 |
| GFPT1 | -7051 |
| DDIT3 | -7047 |
| EIF2AK3 | -7028 |
| HM13 | -7025 |
| FLCN | -7022 |
| RRAGC | -7009 |
| MAFK | -6985 |
| RPL36AL | -6981 |
| MYDGF | -6976 |
| SERP1 | -6964 |
| ATF6 | -6949 |
| KDM6B | -6944 |
| WIPI1 | -6942 |
| ATP6V1D | -6922 |
| RPS19BP1 | -6915 |
| SHC1 | -6910 |
| ATP6V0D1 | -6908 |
| SSR1 | -6907 |
| FKBP14 | -6896 |
| SRPRB | -6893 |
| P4HB | -6884 |
| ERN1 | -6872 |
| CREB3L2 | -6832 |
| ATF5 | -6830 |
| SEC13 | -6812 |
| TXNRD1 | -6806 |
| TRIB3 | -6798 |
| HSPA13 | -6786 |
| TSPYL2 | -6784 |
| PPP1R15A | -6783 |
| FNIP1 | -6782 |
| EGLN2 | -6763 |
| MT1G | -6753 |
| NCOA6 | -6745 |
| RRAGD | -6743 |
| PPARA | -6722 |
| VCP | -6720 |
| HDGF | -6715 |
| MT1F | -6694 |
| PRDX1 | -6673 |
| PSMF1 | -6663 |
| CRTC2 | -6651 |
| SCO2 | -6638 |
| ATP6V0E1 | -6622 |
| SESN2 | -6610 |
| HSPA9 | -6580 |
| COX20 | -6555 |
| HSPH1 | -6524 |
| EXOSC6 | -6503 |
| VHL | -6491 |
| DNAJC7 | -6489 |
| KEAP1 | -6482 |
| EP300 | -6470 |
| TATDN2 | -6467 |
| MAPKAPK2 | -6461 |
| PSME4 | -6450 |
| PSMD2 | -6435 |
| GPX2 | -6408 |
| TPP1 | -6407 |
| POM121 | -6353 |
| DNAJB1 | -6326 |
| ATP6V1E1 | -6271 |
| ATF2 | -6175 |
| TLN1 | -6146 |
| ATP6V0C | -6086 |
| HIRA | -6076 |
| POM121C | -6045 |
| CXXC1 | -6033 |
| ERF | -6016 |
| MEF2D | -5995 |
| AKT1S1 | -5990 |
| CEBPG | -5987 |
| ADD1 | -5966 |
| MBTPS1 | -5958 |
| PSMD6 | -5951 |
| ABCC1 | -5950 |
| ATP6V1C2 | -5929 |
| SIN3A | -5884 |
| RORA | -5875 |
| PPARGC1A | -5869 |
| UBN1 | -5851 |
| FKBP4 | -5807 |
| AGO3 | -5803 |
| PSMA2 | -5801 |
| MAP4K4 | -5792 |
| MAPKAPK3 | -5773 |
| SEC31A | -5766 |
| LRPPRC | -5756 |
| PSMA1 | -5730 |
| ATF4 | -5664 |
| PRKCD | -5638 |
| EZH2 | -5631 |
| SIRT1 | -5628 |
| ATP6V1B2 | -5574 |
| PSMC1 | -5564 |
| SLC38A9 | -5539 |
| PSMD3 | -5535 |
| HSPB8 | -5506 |
| GRB10 | -5504 |
| FNIP2 | -5498 |
| CA9 | -5494 |
| PSME2 | -5481 |
| MED1 | -5451 |
| AQP8 | -5439 |
| NCF2 | -5438 |
| SP1 | -5412 |
| NPAS2 | -5410 |
| HSPA14 | -5393 |
| ATP6V1G1 | -5352 |
| PSMD1 | -5351 |
| BAG3 | -5335 |
| LAMTOR5 | -5293 |
| TERF1 | -5276 |
| NUP205 | -5275 |
| RPL19 | -5254 |
| BAG5 | -5238 |
| HMGA1 | -5226 |
| EIF2S1 | -5190 |
| FOS | -5174 |
| ACTR1A | -5162 |
| DNAJB6 | -5140 |
| RPS7 | -5138 |
| PPP2R5B | -5131 |
| DCP2 | -5125 |
| GSK3B | -5101 |
| UBA52 | -5068 |
| MAPK1 | -5066 |
| CDK4 | -5064 |
| CSNK2A1 | -5040 |
| COX5A | -5033 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| RPA1 | -5008 |
| NUP188 | -4991 |
| FAU | -4990 |
| DEPDC5 | -4989 |
| RPL14 | -4978 |
| BACH1 | -4970 |
| CRTC3 | -4964 |
| ATP6V1C1 | -4946 |
| ANAPC15 | -4945 |
| MT1E | -4931 |
| EPAS1 | -4915 |
| PSMB6 | -4888 |
| PSMC6 | -4878 |
| CDKN2D | -4869 |
| CAPZA1 | -4855 |
| RRAGB | -4819 |
| PSMC4 | -4808 |
| TNRC6C | -4805 |
| SRPRA | -4802 |
| DNAJC2 | -4791 |
| RPS5 | -4778 |
| NUP88 | -4777 |
| EXOSC5 | -4766 |
| HMOX2 | -4742 |
| NUP50 | -4733 |
| RPS11 | -4702 |
| NCOA1 | -4665 |
| RPS19 | -4661 |
| HSPA8 | -4654 |
| RPS28 | -4652 |
| PSMD9 | -4638 |
| CHD9 | -4634 |
| GCN1 | -4627 |
| NR1D1 | -4622 |
| CREBRF | -4582 |
| PARN | -4578 |
| CSNK2A2 | -4546 |
| BAG1 | -4540 |
| COX8A | -4517 |
| MAP2K4 | -4505 |
| SEH1L | -4472 |
| CTDSP2 | -4462 |
| EIF2S2 | -4458 |
| VEGFA | -4456 |
| HSP90AB1 | -4426 |
| ATP6V1H | -4423 |
| NCOR2 | -4409 |
| MAP2K7 | -4399 |
| RPLP1 | -4391 |
| MAPK7 | -4382 |
| NCOR1 | -4374 |
| PSMB7 | -4372 |
| CBX8 | -4370 |
| RPS12 | -4367 |
| COX7A2L | -4360 |
| FBXL17 | -4348 |
| ST13 | -4320 |
| EGLN1 | -4303 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| TERF2IP | -4282 |
| PHC1 | -4280 |
| UBB | -4263 |
| MT1X | -4230 |
| TNRC6B | -4212 |
| PSMA4 | -4211 |
| BMI1 | -4180 |
| HIF1A | -4165 |
| RPL35A | -4159 |
| EEF1A1 | -4138 |
| CUL1 | -4129 |
| PSMC5 | -4091 |
| RPL30 | -4081 |
| RAD50 | -4078 |
| RXRA | -4073 |
| CBX4 | -4063 |
| MAPKAPK5 | -4050 |
| COX4I1 | -4038 |
| RPS9 | -4028 |
| NR3C1 | -4005 |
| COX14 | -4004 |
| UBE2D3 | -3997 |
| RPL18 | -3961 |
| DCTN2 | -3957 |
| MTF1 | -3947 |
| SERPINH1 | -3945 |
| IGFBP1 | -3931 |
| DYNC1LI2 | -3897 |
| CREBBP | -3888 |
| RPL26L1 | -3873 |
| COX7B | -3866 |
| RPS6KA1 | -3857 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| PSME3 | -3813 |
| KLHDC3 | -3802 |
| ATP6V1A | -3777 |
| NUP98 | -3764 |
| RHEB | -3762 |
| EP400 | -3754 |
| LMNA | -3717 |
| RBX1 | -3714 |
| GSK3A | -3684 |
| MTOR | -3683 |
| DEDD2 | -3679 |
| EIF2S3 | -3669 |
| CREB3 | -3650 |
| DCTN5 | -3634 |
| DYNC1H1 | -3614 |
| TXN | -3611 |
| CDKN1A | -3580 |
| STIP1 | -3571 |
| RPL28 | -3546 |
| GSR | -3534 |
| RPSA | -3520 |
| NFKB1 | -3507 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| EXOSC3 | -3453 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| HSPA6 | -3353 |
| RPS24 | -3352 |
| MAP2K3 | -3342 |
| SH3BP4 | -3331 |
| RBBP4 | -3297 |
| CCAR2 | -3268 |
| RPS14 | -3261 |
| DNAJA2 | -3258 |
| ZBTB17 | -3194 |
| RPS27L | -3180 |
| COX6B1 | -3158 |
| RPS10 | -3155 |
| SEM1 | -3130 |
| COX6A1 | -3107 |
| PSMA3 | -3078 |
| CUL3 | -3056 |
| RPS6KA3 | -3030 |
| HBA1 | -3024 |
| RPS15A | -3019 |
| SCO1 | -3018 |
| ELOB | -3004 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| APOB | -2964 |
| JUN | -2934 |
| PSMD8 | -2928 |
| RPS21 | -2927 |
| EIF2AK1 | -2921 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| DYNC1I2 | -2780 |
| RPS27A | -2773 |
| PSMA5 | -2715 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RELA | -2632 |
| LAMTOR3 | -2631 |
| RPS13 | -2581 |
| TFDP1 | -2579 |
| PSMD13 | -2577 |
| RPL4 | -2563 |
| MDM4 | -2561 |
| DYNC1LI1 | -2519 |
| NFYA | -2482 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| HSF1 | -2414 |
| PSMC2 | -2389 |
| MAP2K6 | -2351 |
| PSME1 | -2348 |
| DNAJA1 | -2311 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| ETS2 | -2186 |
| TNFRSF21 | -2173 |
| CABIN1 | -2162 |
| RPS4Y1 | -2120 |
| NFE2L2 | -2108 |
| RPL27 | -2070 |
| CCNE2 | -2024 |
| TP53 | -2020 |
| RAI1 | -2008 |
| DCTN4 | -1937 |
| NUP214 | -1926 |
| PSMB3 | -1915 |
| RPL23 | -1913 |
| UBE2S | -1872 |
| XPO1 | -1864 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| EHMT1 | -1678 |
| CLOCK | -1648 |
| ANAPC2 | -1639 |
| DCTN1 | -1635 |
| TBL1X | -1621 |
| ARFGAP1 | -1587 |
| DIS3 | -1573 |
| CAPZA2 | -1549 |
| ANAPC11 | -1544 |
| CDC27 | -1529 |
| PSMC3 | -1509 |
| NDC1 | -1490 |
| EIF2AK4 | -1455 |
| BLVRA | -1440 |
| LY96 | -1339 |
| RPL15 | -1313 |
| PRDX5 | -1274 |
| CAPZB | -1169 |
| RPL3 | -1165 |
| RPS6KA2 | -1149 |
| PSMB4 | -1144 |
| CEBPB | -1129 |
| MT2A | -1121 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| HSP90AA1 | -1030 |
| KHSRP | -994 |
| RPL12 | -983 |
| PRDX2 | -961 |
| MDM2 | -956 |
| RPS25 | -937 |
| UBE2D2 | -913 |
| COX16 | -910 |
| PSMA7 | -892 |
| MRPL18 | -882 |
| ATP6V1F | -868 |
| SLC46A1 | -835 |
| CDKN1B | -786 |
| LAMTOR1 | -774 |
| PSMB5 | -742 |
| RPL13 | -706 |
| MAPK8 | -700 |
| NFYC | -690 |
| SKP1 | -544 |
| ATP6V1E2 | -534 |
| RPL5 | -495 |
| PSMD11 | -432 |
| NDUFA4 | -390 |
| ARNTL | -359 |
| NUP160 | -329 |
| DCTN6 | -318 |
| MT1A | -309 |
| NUP62 | -299 |
| TXN2 | -243 |
| RPL22L1 | -214 |
| ERO1A | -198 |
| CDC26 | -197 |
| RPS3A | -179 |
| RPS27 | -152 |
| LAMTOR2 | -148 |
| PSMA6 | -126 |
| PRDX6 | -54 |
| RANBP2 | -4 |
| HDAC3 | 38 |
| YWHAE | 129 |
| PRDX3 | 165 |
| TCIRG1 | 180 |
| YIF1A | 195 |
| FZR1 | 201 |
| MAPK11 | 251 |
| RPL9 | 261 |
| NUDT2 | 301 |
| ANAPC4 | 305 |
| TXNRD2 | 308 |
| SURF1 | 327 |
| RPL31 | 330 |
| COX6C | 344 |
| SUZ12 | 346 |
| CUL2 | 359 |
| EHMT2 | 400 |
| RPTOR | 407 |
| RPS26 | 419 |
| PSMB10 | 423 |
| E2F3 | 444 |
| RB1 | 470 |
| EXOSC8 | 472 |
| CREB1 | 474 |
| CYCS | 562 |
| TPR | 565 |
| NRIP1 | 570 |
| PDIA5 | 579 |
| BMT2 | 638 |
| ELOC | 645 |
| ATP6V1G2 | 690 |
| COX5B | 704 |
| MT-CO2 | 716 |
| HIGD1A | 720 |
| GPX8 | 743 |
| ATP6V0D2 | 747 |
| UBC | 779 |
| BLVRB | 811 |
| PHC3 | 843 |
| HSPA4 | 925 |
| CRYAB | 939 |
| KDELR3 | 976 |
| ARNT | 1014 |
| SULT1A3 | 1040 |
| PSMB1 | 1054 |
| CDC16 | 1175 |
| GOSR2 | 1238 |
| BAG2 | 1269 |
| NUP133 | 1362 |
| HSBP1 | 1372 |
| RPL21 | 1385 |
| TBL1XR1 | 1404 |
| PREB | 1446 |
| DCTN3 | 1457 |
| COX7C | 1483 |
| ATM | 1503 |
| NR3C2 | 1520 |
| COX11 | 1523 |
| KAT5 | 1580 |
| CDKN2B | 1710 |
| CAMK2D | 1711 |
| MAPK9 | 1760 |
| TNRC6A | 1824 |
| LAMTOR4 | 1834 |
| HSPA1A | 1835 |
| MLST8 | 1875 |
| PSMB2 | 1876 |
| ANAPC1 | 1998 |
| EPO | 2073 |
| ATP7A | 2111 |
| RPL22 | 2142 |
| ITFG2 | 2143 |
| CAMK2G | 2145 |
| TGS1 | 2148 |
| CYBA | 2202 |
| MINK1 | 2261 |
| MAPK14 | 2269 |
| SMARCD3 | 2305 |
| EED | 2369 |
| NUP58 | 2380 |
| RNF2 | 2454 |
| ATF3 | 2488 |
| DYNLL1 | 2509 |
| EGLN3 | 2588 |
| RRAGA | 2609 |
| NUP153 | 2712 |
| GPX7 | 2739 |
| CCNE1 | 2754 |
| NUP43 | 2808 |
| RPL36A | 2875 |
| CBX6 | 2911 |
| MIOS | 2912 |
| MAPK10 | 2952 |
| AAAS | 2965 |
| CRTC1 | 2969 |
| LIMD1 | 2987 |
| ACD | 3041 |
| ALB | 3096 |
| GPX1 | 3161 |
| EXOSC4 | 3220 |
| EXOSC9 | 3293 |
| PTK6 | 3304 |
| NUP54 | 3310 |
| EXTL2 | 3353 |
| HSPA2 | 3418 |
| EXOSC1 | 3486 |
| CARM1 | 3517 |
| UBE2D1 | 3523 |
| ETS1 | 3554 |
| EXTL3 | 3575 |
| CXCL8 | 3625 |
| ATOX1 | 3659 |
| MBTPS2 | 3687 |
| CDKN2A | 3704 |
| PHC2 | 3713 |
| UBE2E1 | 3733 |
| PTGES3 | 3734 |
| EXOSC2 | 3779 |
| COX18 | 3788 |
| ASF1A | 3905 |
| HSPA4L | 3936 |
| ANAPC5 | 3942 |
| BAG4 | 4019 |
| SIN3B | 4029 |
| RING1 | 4067 |
| MRE11 | 4100 |
| CDK2 | 4114 |
| COX19 | 4126 |
| ACADVL | 4157 |
| NPRL3 | 4164 |
| WTIP | 4170 |
| NUP85 | 4178 |
| CITED2 | 4227 |
| CDKN2C | 4232 |
| STAT3 | 4253 |
| IGFBP7 | 4272 |
| HIF1AN | 4302 |
| PSMD12 | 4303 |
| AGO1 | 4307 |
| TINF2 | 4357 |
| CUL7 | 4377 |
| RAE1 | 4394 |
| CSNK2B | 4415 |
| IMPACT | 4432 |
| HIF3A | 4444 |
| WDR24 | 4466 |
| KPTN | 4478 |
| TERF2 | 4479 |
| ID1 | 4484 |
| NBN | 4533 |
| ATP6V1B1 | 4549 |
| CAMK2A | 4566 |
| PSMD4 | 4567 |
| HMOX1 | 4592 |
| STAP2 | 4664 |
| PLA2G4B | 4716 |
| CDK6 | 4754 |
| NCOA2 | 4780 |
| HELZ2 | 4786 |
| NUP155 | 4796 |
| TFDP2 | 4856 |
| CCS | 4860 |
| TNIK | 4872 |
| NPRL2 | 4876 |
| WDR59 | 4915 |
| PSMD10 | 4933 |
| PSMD7 | 4942 |
| SESN1 | 4963 |
| CAT | 5018 |
| SZT2 | 5052 |
| NFYB | 5091 |
| FABP1 | 5092 |
| PSMD5 | 5116 |
| RBBP7 | 5134 |
| EXOSC7 | 5196 |
| FKBP5 | 5342 |
| H2AFX | 5356 |
| GPX3 | 5394 |
| ATR | 5478 |
| HSPA12A | 5480 |
| PSMB9 | 5491 |
| TACO1 | 5527 |
| ACTR10 | 5570 |
| COL4A6 | 5592 |
| HMGA2 | 5643 |
| ATP6V0E2 | 5683 |
| SOD1 | 5779 |
| NUP93 | 5831 |
| CREB3L4 | 5920 |
| XBP1 | 5937 |
| SKP2 | 5946 |
| HDAC6 | 5953 |
| PSMD14 | 5974 |
| NUP35 | 5982 |
| CREB3L3 | 5999 |
| AJUBA | 6013 |
| DYNLL2 | 6044 |
| ANAPC10 | 6071 |
| NUP107 | 6076 |
| CDC23 | 6113 |
| POT1 | 6132 |
| HIKESHI | 6144 |
| ASNS | 6208 |
| ANAPC7 | 6249 |
| DDX11 | 6254 |
| ANAPC16 | 6307 |
| RPA3 | 6375 |
| MOV10 | 6408 |
| E2F2 | 6426 |
| MT-CO1 | 6493 |
| AGO4 | 6581 |
| CCNA2 | 6594 |
| MAPK3 | 6640 |
| SCMH1 | 6656 |
| NUP210 | 6802 |
| CHAC1 | 6845 |
| EXTL1 | 6941 |
| CBX2 | 6958 |
| RPA2 | 6961 |
| APOA1 | 6993 |
| E2F1 | 7096 |
| NUP37 | 7100 |
| LMNB1 | 7101 |
| UBE2C | 7137 |
| MT-CO3 | 7316 |
| SOD2 | 7342 |
| TXNIP | 7384 |
Cellular responses to stress
| 156 | |
|---|---|
| set | Cellular responses to stress |
| setSize | 633 |
| pANOVA | 2.2e-20 |
| s.dist | -0.217 |
| p.adjustANOVA | 1.51e-17 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| HSPA5 | -7144 |
| CALR | -7142 |
| DNAJB11 | -7141 |
| HYOU1 | -7140 |
| HERPUD1 | -7137 |
| DNAJC3 | -7131 |
| HSP90B1 | -7129 |
| DNAJB9 | -7125 |
| SYVN1 | -7108 |
| PDIA6 | -7106 |
| EDEM1 | -7103 |
| WFS1 | -7096 |
| ATP6V0B | -7064 |
| GFPT1 | -7051 |
| DDIT3 | -7047 |
| EIF2AK3 | -7028 |
| HM13 | -7025 |
| FLCN | -7022 |
| RRAGC | -7009 |
| MAFK | -6985 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HSPA5 | -7144 |
| CALR | -7142 |
| DNAJB11 | -7141 |
| HYOU1 | -7140 |
| HERPUD1 | -7137 |
| DNAJC3 | -7131 |
| HSP90B1 | -7129 |
| DNAJB9 | -7125 |
| SYVN1 | -7108 |
| PDIA6 | -7106 |
| EDEM1 | -7103 |
| WFS1 | -7096 |
| ATP6V0B | -7064 |
| GFPT1 | -7051 |
| DDIT3 | -7047 |
| EIF2AK3 | -7028 |
| HM13 | -7025 |
| FLCN | -7022 |
| RRAGC | -7009 |
| MAFK | -6985 |
| RPL36AL | -6981 |
| MYDGF | -6976 |
| SERP1 | -6964 |
| ATF6 | -6949 |
| KDM6B | -6944 |
| WIPI1 | -6942 |
| ATP6V1D | -6922 |
| RPS19BP1 | -6915 |
| SHC1 | -6910 |
| ATP6V0D1 | -6908 |
| SSR1 | -6907 |
| FKBP14 | -6896 |
| SRPRB | -6893 |
| P4HB | -6884 |
| ERN1 | -6872 |
| CREB3L2 | -6832 |
| ATF5 | -6830 |
| SEC13 | -6812 |
| TXNRD1 | -6806 |
| TRIB3 | -6798 |
| HSPA13 | -6786 |
| TSPYL2 | -6784 |
| PPP1R15A | -6783 |
| FNIP1 | -6782 |
| EGLN2 | -6763 |
| NCOA6 | -6745 |
| RRAGD | -6743 |
| PPARA | -6722 |
| VCP | -6720 |
| HDGF | -6715 |
| PRDX1 | -6673 |
| PSMF1 | -6663 |
| CRTC2 | -6651 |
| SCO2 | -6638 |
| ATP6V0E1 | -6622 |
| SESN2 | -6610 |
| HSPA9 | -6580 |
| COX20 | -6555 |
| HSPH1 | -6524 |
| EXOSC6 | -6503 |
| VHL | -6491 |
| DNAJC7 | -6489 |
| KEAP1 | -6482 |
| EP300 | -6470 |
| TATDN2 | -6467 |
| MAPKAPK2 | -6461 |
| PSME4 | -6450 |
| PSMD2 | -6435 |
| GPX2 | -6408 |
| TPP1 | -6407 |
| POM121 | -6353 |
| DNAJB1 | -6326 |
| ATP6V1E1 | -6271 |
| ATF2 | -6175 |
| TLN1 | -6146 |
| ATP6V0C | -6086 |
| HIRA | -6076 |
| POM121C | -6045 |
| CXXC1 | -6033 |
| ERF | -6016 |
| MEF2D | -5995 |
| AKT1S1 | -5990 |
| CEBPG | -5987 |
| ADD1 | -5966 |
| MBTPS1 | -5958 |
| PSMD6 | -5951 |
| ABCC1 | -5950 |
| ATP6V1C2 | -5929 |
| SIN3A | -5884 |
| RORA | -5875 |
| PPARGC1A | -5869 |
| UBN1 | -5851 |
| FKBP4 | -5807 |
| AGO3 | -5803 |
| PSMA2 | -5801 |
| MAP4K4 | -5792 |
| MAPKAPK3 | -5773 |
| SEC31A | -5766 |
| LRPPRC | -5756 |
| PSMA1 | -5730 |
| ATF4 | -5664 |
| PRKCD | -5638 |
| EZH2 | -5631 |
| SIRT1 | -5628 |
| ATP6V1B2 | -5574 |
| PSMC1 | -5564 |
| SLC38A9 | -5539 |
| PSMD3 | -5535 |
| HSPB8 | -5506 |
| GRB10 | -5504 |
| FNIP2 | -5498 |
| CA9 | -5494 |
| PSME2 | -5481 |
| MED1 | -5451 |
| AQP8 | -5439 |
| NCF2 | -5438 |
| SP1 | -5412 |
| NPAS2 | -5410 |
| HSPA14 | -5393 |
| ATP6V1G1 | -5352 |
| PSMD1 | -5351 |
| BAG3 | -5335 |
| LAMTOR5 | -5293 |
| TERF1 | -5276 |
| NUP205 | -5275 |
| RPL19 | -5254 |
| BAG5 | -5238 |
| HMGA1 | -5226 |
| EIF2S1 | -5190 |
| FOS | -5174 |
| ACTR1A | -5162 |
| DNAJB6 | -5140 |
| RPS7 | -5138 |
| PPP2R5B | -5131 |
| DCP2 | -5125 |
| GSK3B | -5101 |
| UBA52 | -5068 |
| MAPK1 | -5066 |
| CDK4 | -5064 |
| CSNK2A1 | -5040 |
| COX5A | -5033 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| RPA1 | -5008 |
| NUP188 | -4991 |
| FAU | -4990 |
| DEPDC5 | -4989 |
| RPL14 | -4978 |
| BACH1 | -4970 |
| CRTC3 | -4964 |
| ATP6V1C1 | -4946 |
| ANAPC15 | -4945 |
| EPAS1 | -4915 |
| PSMB6 | -4888 |
| PSMC6 | -4878 |
| CDKN2D | -4869 |
| CAPZA1 | -4855 |
| RRAGB | -4819 |
| PSMC4 | -4808 |
| TNRC6C | -4805 |
| SRPRA | -4802 |
| DNAJC2 | -4791 |
| RPS5 | -4778 |
| NUP88 | -4777 |
| EXOSC5 | -4766 |
| HMOX2 | -4742 |
| NUP50 | -4733 |
| RPS11 | -4702 |
| NCOA1 | -4665 |
| RPS19 | -4661 |
| HSPA8 | -4654 |
| RPS28 | -4652 |
| PSMD9 | -4638 |
| CHD9 | -4634 |
| GCN1 | -4627 |
| NR1D1 | -4622 |
| CREBRF | -4582 |
| PARN | -4578 |
| CSNK2A2 | -4546 |
| BAG1 | -4540 |
| COX8A | -4517 |
| MAP2K4 | -4505 |
| SEH1L | -4472 |
| CTDSP2 | -4462 |
| EIF2S2 | -4458 |
| VEGFA | -4456 |
| HSP90AB1 | -4426 |
| ATP6V1H | -4423 |
| NCOR2 | -4409 |
| MAP2K7 | -4399 |
| RPLP1 | -4391 |
| MAPK7 | -4382 |
| NCOR1 | -4374 |
| PSMB7 | -4372 |
| CBX8 | -4370 |
| RPS12 | -4367 |
| COX7A2L | -4360 |
| FBXL17 | -4348 |
| ST13 | -4320 |
| EGLN1 | -4303 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| TERF2IP | -4282 |
| PHC1 | -4280 |
| UBB | -4263 |
| TNRC6B | -4212 |
| PSMA4 | -4211 |
| BMI1 | -4180 |
| HIF1A | -4165 |
| RPL35A | -4159 |
| EEF1A1 | -4138 |
| CUL1 | -4129 |
| PSMC5 | -4091 |
| RPL30 | -4081 |
| RAD50 | -4078 |
| RXRA | -4073 |
| CBX4 | -4063 |
| MAPKAPK5 | -4050 |
| COX4I1 | -4038 |
| RPS9 | -4028 |
| NR3C1 | -4005 |
| COX14 | -4004 |
| UBE2D3 | -3997 |
| RPL18 | -3961 |
| DCTN2 | -3957 |
| SERPINH1 | -3945 |
| IGFBP1 | -3931 |
| DYNC1LI2 | -3897 |
| CREBBP | -3888 |
| RPL26L1 | -3873 |
| COX7B | -3866 |
| RPS6KA1 | -3857 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| PSME3 | -3813 |
| KLHDC3 | -3802 |
| ATP6V1A | -3777 |
| NUP98 | -3764 |
| RHEB | -3762 |
| EP400 | -3754 |
| LMNA | -3717 |
| RBX1 | -3714 |
| GSK3A | -3684 |
| MTOR | -3683 |
| DEDD2 | -3679 |
| EIF2S3 | -3669 |
| CREB3 | -3650 |
| DCTN5 | -3634 |
| DYNC1H1 | -3614 |
| TXN | -3611 |
| CDKN1A | -3580 |
| STIP1 | -3571 |
| RPL28 | -3546 |
| GSR | -3534 |
| RPSA | -3520 |
| NFKB1 | -3507 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| EXOSC3 | -3453 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| HSPA6 | -3353 |
| RPS24 | -3352 |
| MAP2K3 | -3342 |
| SH3BP4 | -3331 |
| RBBP4 | -3297 |
| CCAR2 | -3268 |
| RPS14 | -3261 |
| DNAJA2 | -3258 |
| ZBTB17 | -3194 |
| RPS27L | -3180 |
| COX6B1 | -3158 |
| RPS10 | -3155 |
| SEM1 | -3130 |
| COX6A1 | -3107 |
| PSMA3 | -3078 |
| CUL3 | -3056 |
| RPS6KA3 | -3030 |
| HBA1 | -3024 |
| RPS15A | -3019 |
| SCO1 | -3018 |
| ELOB | -3004 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| APOB | -2964 |
| JUN | -2934 |
| PSMD8 | -2928 |
| RPS21 | -2927 |
| EIF2AK1 | -2921 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| DYNC1I2 | -2780 |
| RPS27A | -2773 |
| PSMA5 | -2715 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RELA | -2632 |
| LAMTOR3 | -2631 |
| RPS13 | -2581 |
| TFDP1 | -2579 |
| PSMD13 | -2577 |
| RPL4 | -2563 |
| MDM4 | -2561 |
| DYNC1LI1 | -2519 |
| NFYA | -2482 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| HSF1 | -2414 |
| PSMC2 | -2389 |
| MAP2K6 | -2351 |
| PSME1 | -2348 |
| DNAJA1 | -2311 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| ETS2 | -2186 |
| TNFRSF21 | -2173 |
| CABIN1 | -2162 |
| RPS4Y1 | -2120 |
| NFE2L2 | -2108 |
| RPL27 | -2070 |
| CCNE2 | -2024 |
| TP53 | -2020 |
| RAI1 | -2008 |
| DCTN4 | -1937 |
| NUP214 | -1926 |
| PSMB3 | -1915 |
| RPL23 | -1913 |
| UBE2S | -1872 |
| XPO1 | -1864 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| EHMT1 | -1678 |
| CLOCK | -1648 |
| ANAPC2 | -1639 |
| DCTN1 | -1635 |
| TBL1X | -1621 |
| ARFGAP1 | -1587 |
| DIS3 | -1573 |
| CAPZA2 | -1549 |
| ANAPC11 | -1544 |
| CDC27 | -1529 |
| PSMC3 | -1509 |
| NDC1 | -1490 |
| EIF2AK4 | -1455 |
| BLVRA | -1440 |
| LY96 | -1339 |
| RPL15 | -1313 |
| PRDX5 | -1274 |
| CAPZB | -1169 |
| RPL3 | -1165 |
| RPS6KA2 | -1149 |
| PSMB4 | -1144 |
| CEBPB | -1129 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| HSP90AA1 | -1030 |
| KHSRP | -994 |
| RPL12 | -983 |
| PRDX2 | -961 |
| MDM2 | -956 |
| RPS25 | -937 |
| UBE2D2 | -913 |
| COX16 | -910 |
| PSMA7 | -892 |
| MRPL18 | -882 |
| ATP6V1F | -868 |
| SLC46A1 | -835 |
| CDKN1B | -786 |
| LAMTOR1 | -774 |
| PSMB5 | -742 |
| RPL13 | -706 |
| MAPK8 | -700 |
| NFYC | -690 |
| SKP1 | -544 |
| ATP6V1E2 | -534 |
| RPL5 | -495 |
| PSMD11 | -432 |
| NDUFA4 | -390 |
| ARNTL | -359 |
| NUP160 | -329 |
| DCTN6 | -318 |
| NUP62 | -299 |
| TXN2 | -243 |
| RPL22L1 | -214 |
| ERO1A | -198 |
| CDC26 | -197 |
| RPS3A | -179 |
| RPS27 | -152 |
| LAMTOR2 | -148 |
| PSMA6 | -126 |
| PRDX6 | -54 |
| RANBP2 | -4 |
| HDAC3 | 38 |
| YWHAE | 129 |
| PRDX3 | 165 |
| TCIRG1 | 180 |
| YIF1A | 195 |
| FZR1 | 201 |
| MAPK11 | 251 |
| RPL9 | 261 |
| NUDT2 | 301 |
| ANAPC4 | 305 |
| TXNRD2 | 308 |
| SURF1 | 327 |
| RPL31 | 330 |
| COX6C | 344 |
| SUZ12 | 346 |
| CUL2 | 359 |
| EHMT2 | 400 |
| RPTOR | 407 |
| RPS26 | 419 |
| PSMB10 | 423 |
| E2F3 | 444 |
| RB1 | 470 |
| EXOSC8 | 472 |
| CREB1 | 474 |
| CYCS | 562 |
| TPR | 565 |
| NRIP1 | 570 |
| PDIA5 | 579 |
| BMT2 | 638 |
| ELOC | 645 |
| ATP6V1G2 | 690 |
| COX5B | 704 |
| MT-CO2 | 716 |
| HIGD1A | 720 |
| GPX8 | 743 |
| ATP6V0D2 | 747 |
| UBC | 779 |
| BLVRB | 811 |
| PHC3 | 843 |
| HSPA4 | 925 |
| CRYAB | 939 |
| KDELR3 | 976 |
| ARNT | 1014 |
| SULT1A3 | 1040 |
| PSMB1 | 1054 |
| CDC16 | 1175 |
| GOSR2 | 1238 |
| BAG2 | 1269 |
| NUP133 | 1362 |
| HSBP1 | 1372 |
| RPL21 | 1385 |
| TBL1XR1 | 1404 |
| PREB | 1446 |
| DCTN3 | 1457 |
| COX7C | 1483 |
| ATM | 1503 |
| NR3C2 | 1520 |
| COX11 | 1523 |
| KAT5 | 1580 |
| CDKN2B | 1710 |
| CAMK2D | 1711 |
| MAPK9 | 1760 |
| TNRC6A | 1824 |
| LAMTOR4 | 1834 |
| HSPA1A | 1835 |
| MLST8 | 1875 |
| PSMB2 | 1876 |
| ANAPC1 | 1998 |
| EPO | 2073 |
| ATP7A | 2111 |
| RPL22 | 2142 |
| ITFG2 | 2143 |
| CAMK2G | 2145 |
| TGS1 | 2148 |
| CYBA | 2202 |
| MINK1 | 2261 |
| MAPK14 | 2269 |
| SMARCD3 | 2305 |
| EED | 2369 |
| NUP58 | 2380 |
| RNF2 | 2454 |
| ATF3 | 2488 |
| DYNLL1 | 2509 |
| EGLN3 | 2588 |
| RRAGA | 2609 |
| NUP153 | 2712 |
| GPX7 | 2739 |
| CCNE1 | 2754 |
| NUP43 | 2808 |
| RPL36A | 2875 |
| CBX6 | 2911 |
| MIOS | 2912 |
| MAPK10 | 2952 |
| AAAS | 2965 |
| CRTC1 | 2969 |
| LIMD1 | 2987 |
| ACD | 3041 |
| ALB | 3096 |
| GPX1 | 3161 |
| EXOSC4 | 3220 |
| EXOSC9 | 3293 |
| PTK6 | 3304 |
| NUP54 | 3310 |
| EXTL2 | 3353 |
| HSPA2 | 3418 |
| EXOSC1 | 3486 |
| CARM1 | 3517 |
| UBE2D1 | 3523 |
| ETS1 | 3554 |
| EXTL3 | 3575 |
| CXCL8 | 3625 |
| ATOX1 | 3659 |
| MBTPS2 | 3687 |
| CDKN2A | 3704 |
| PHC2 | 3713 |
| UBE2E1 | 3733 |
| PTGES3 | 3734 |
| EXOSC2 | 3779 |
| COX18 | 3788 |
| ASF1A | 3905 |
| HSPA4L | 3936 |
| ANAPC5 | 3942 |
| BAG4 | 4019 |
| SIN3B | 4029 |
| RING1 | 4067 |
| MRE11 | 4100 |
| CDK2 | 4114 |
| COX19 | 4126 |
| ACADVL | 4157 |
| NPRL3 | 4164 |
| WTIP | 4170 |
| NUP85 | 4178 |
| CITED2 | 4227 |
| CDKN2C | 4232 |
| STAT3 | 4253 |
| IGFBP7 | 4272 |
| HIF1AN | 4302 |
| PSMD12 | 4303 |
| AGO1 | 4307 |
| TINF2 | 4357 |
| CUL7 | 4377 |
| RAE1 | 4394 |
| CSNK2B | 4415 |
| IMPACT | 4432 |
| HIF3A | 4444 |
| WDR24 | 4466 |
| KPTN | 4478 |
| TERF2 | 4479 |
| ID1 | 4484 |
| NBN | 4533 |
| ATP6V1B1 | 4549 |
| CAMK2A | 4566 |
| PSMD4 | 4567 |
| HMOX1 | 4592 |
| STAP2 | 4664 |
| PLA2G4B | 4716 |
| CDK6 | 4754 |
| NCOA2 | 4780 |
| HELZ2 | 4786 |
| NUP155 | 4796 |
| TFDP2 | 4856 |
| CCS | 4860 |
| TNIK | 4872 |
| NPRL2 | 4876 |
| WDR59 | 4915 |
| PSMD10 | 4933 |
| PSMD7 | 4942 |
| SESN1 | 4963 |
| CAT | 5018 |
| SZT2 | 5052 |
| NFYB | 5091 |
| FABP1 | 5092 |
| PSMD5 | 5116 |
| RBBP7 | 5134 |
| EXOSC7 | 5196 |
| FKBP5 | 5342 |
| H2AFX | 5356 |
| GPX3 | 5394 |
| ATR | 5478 |
| HSPA12A | 5480 |
| PSMB9 | 5491 |
| TACO1 | 5527 |
| ACTR10 | 5570 |
| COL4A6 | 5592 |
| HMGA2 | 5643 |
| ATP6V0E2 | 5683 |
| SOD1 | 5779 |
| NUP93 | 5831 |
| CREB3L4 | 5920 |
| XBP1 | 5937 |
| SKP2 | 5946 |
| HDAC6 | 5953 |
| PSMD14 | 5974 |
| NUP35 | 5982 |
| CREB3L3 | 5999 |
| AJUBA | 6013 |
| DYNLL2 | 6044 |
| ANAPC10 | 6071 |
| NUP107 | 6076 |
| CDC23 | 6113 |
| POT1 | 6132 |
| HIKESHI | 6144 |
| ASNS | 6208 |
| ANAPC7 | 6249 |
| DDX11 | 6254 |
| ANAPC16 | 6307 |
| RPA3 | 6375 |
| MOV10 | 6408 |
| E2F2 | 6426 |
| MT-CO1 | 6493 |
| AGO4 | 6581 |
| CCNA2 | 6594 |
| MAPK3 | 6640 |
| SCMH1 | 6656 |
| NUP210 | 6802 |
| CHAC1 | 6845 |
| EXTL1 | 6941 |
| CBX2 | 6958 |
| RPA2 | 6961 |
| APOA1 | 6993 |
| E2F1 | 7096 |
| NUP37 | 7100 |
| LMNB1 | 7101 |
| UBE2C | 7137 |
| MT-CO3 | 7316 |
| SOD2 | 7342 |
| TXNIP | 7384 |
Infectious disease
| 509 | |
|---|---|
| set | Infectious disease |
| setSize | 637 |
| pANOVA | 1.06e-18 |
| s.dist | -0.206 |
| p.adjustANOVA | 4.88e-16 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CALR | -7142 |
| DNAJC3 | -7131 |
| CANX | -7092 |
| ANTXR2 | -7077 |
| MAGT1 | -7045 |
| MAP1LC3B | -7040 |
| RAMP1 | -7037 |
| RPN1 | -7013 |
| RPL36AL | -6981 |
| DVL3 | -6967 |
| CTSL | -6951 |
| ATP1B3 | -6941 |
| TGFB1 | -6934 |
| MET | -6878 |
| SFPQ | -6854 |
| ACTG1 | -6841 |
| SEC13 | -6812 |
| TXNRD1 | -6806 |
| ST3GAL4 | -6801 |
| STT3A | -6796 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CALR | -7142 |
| DNAJC3 | -7131 |
| CANX | -7092 |
| ANTXR2 | -7077 |
| MAGT1 | -7045 |
| MAP1LC3B | -7040 |
| RAMP1 | -7037 |
| RPN1 | -7013 |
| RPL36AL | -6981 |
| DVL3 | -6967 |
| CTSL | -6951 |
| ATP1B3 | -6941 |
| TGFB1 | -6934 |
| MET | -6878 |
| SFPQ | -6854 |
| ACTG1 | -6841 |
| SEC13 | -6812 |
| TXNRD1 | -6806 |
| ST3GAL4 | -6801 |
| STT3A | -6796 |
| ATP1A1 | -6777 |
| ST6GALNAC4 | -6726 |
| VCP | -6720 |
| KPNA1 | -6701 |
| FURIN | -6683 |
| DDX5 | -6665 |
| PSMF1 | -6663 |
| ATP1B1 | -6624 |
| CHMP4C | -6557 |
| WASL | -6543 |
| VHL | -6491 |
| KEAP1 | -6482 |
| BRD4 | -6479 |
| RAN | -6476 |
| PSME4 | -6450 |
| CLTA | -6439 |
| PSMD2 | -6435 |
| DDOST | -6429 |
| TCEA1 | -6409 |
| P2RY11 | -6403 |
| MGAT1 | -6401 |
| KPNB1 | -6379 |
| IPO5 | -6366 |
| POM121 | -6353 |
| BRMS1 | -6309 |
| NT5E | -6296 |
| UVRAG | -6290 |
| FNTA | -6282 |
| MGAT4B | -6279 |
| LCK | -6250 |
| DAD1 | -6240 |
| CLTC | -6220 |
| RPN2 | -6193 |
| TAF4 | -6108 |
| ARPC4 | -6094 |
| ITPR3 | -6088 |
| MAP2K2 | -6087 |
| ADM2 | -6068 |
| POM121C | -6045 |
| PTHLH | -6042 |
| ARF1 | -6021 |
| PSMD6 | -5951 |
| PRKCSH | -5934 |
| MYO9B | -5920 |
| ST3GAL1 | -5905 |
| FXYD2 | -5865 |
| MGAT5 | -5854 |
| HTR7 | -5841 |
| ADAM17 | -5836 |
| GTF2E2 | -5813 |
| RAB7A | -5810 |
| FKBP4 | -5807 |
| PSMA2 | -5801 |
| SUPT5H | -5767 |
| GTF2H1 | -5744 |
| ELK1 | -5733 |
| PSMA1 | -5730 |
| WASF1 | -5712 |
| CBL | -5708 |
| GTF2B | -5704 |
| CBLL1 | -5694 |
| CHMP1A | -5693 |
| CRK | -5650 |
| EZH2 | -5631 |
| MTA2 | -5619 |
| PSMC1 | -5564 |
| PSMD3 | -5535 |
| EDEM2 | -5520 |
| ISG15 | -5488 |
| PSME2 | -5481 |
| POLR2L | -5471 |
| CDK7 | -5444 |
| BRK1 | -5431 |
| RAB5A | -5408 |
| EGFR | -5383 |
| PDCD6IP | -5380 |
| PSMD1 | -5351 |
| CSNK1A1 | -5349 |
| ACTR3 | -5296 |
| MYO10 | -5290 |
| NELFA | -5284 |
| POLR2F | -5283 |
| TAF13 | -5280 |
| NUP205 | -5275 |
| RPL19 | -5254 |
| SAP30 | -5230 |
| HMGA1 | -5226 |
| PIK3C3 | -5220 |
| FKBP1A | -5189 |
| TBK1 | -5169 |
| RPS7 | -5138 |
| FUT8 | -5134 |
| GSK3B | -5101 |
| VAMP2 | -5088 |
| UBA52 | -5068 |
| MAPK1 | -5066 |
| ACTB | -5057 |
| EEF2 | -5049 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| CHMP4B | -5021 |
| MGAT4A | -5018 |
| RPS15 | -5010 |
| PLK2 | -5005 |
| NUP188 | -4991 |
| FAU | -4990 |
| RPL14 | -4978 |
| JAK1 | -4963 |
| PAK2 | -4957 |
| IL6R | -4943 |
| PSMB6 | -4888 |
| PSMC6 | -4878 |
| ENO1 | -4866 |
| TRIM27 | -4835 |
| CHD4 | -4830 |
| PGK1 | -4810 |
| PSMC4 | -4808 |
| RPS5 | -4778 |
| NUP88 | -4777 |
| GRSF1 | -4747 |
| NUP50 | -4733 |
| MYH9 | -4726 |
| RPS11 | -4702 |
| VPS37B | -4696 |
| CCNT1 | -4690 |
| POLR2E | -4667 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| VAV3 | -4642 |
| PSMD9 | -4638 |
| VPS37C | -4620 |
| GNAI3 | -4609 |
| AP2M1 | -4603 |
| KPNA2 | -4575 |
| MBD3 | -4543 |
| SSRP1 | -4525 |
| GPS2 | -4524 |
| ST3GAL2 | -4518 |
| GNB2 | -4514 |
| MAP2K4 | -4505 |
| TAF4B | -4483 |
| ABI1 | -4478 |
| SEH1L | -4472 |
| CTDP1 | -4461 |
| VEGFA | -4456 |
| PPIA | -4443 |
| ARPC1B | -4429 |
| HSP90AB1 | -4426 |
| ATP6V1H | -4423 |
| NCOR2 | -4409 |
| HBEGF | -4402 |
| RNGTT | -4400 |
| MAP2K7 | -4399 |
| RPLP1 | -4391 |
| NCOR1 | -4374 |
| PSMB7 | -4372 |
| RPS12 | -4367 |
| KPNA3 | -4357 |
| PTK2 | -4346 |
| ITPR1 | -4321 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| PRMT1 | -4281 |
| UBB | -4263 |
| PSMA4 | -4211 |
| HGS | -4210 |
| AP1S2 | -4204 |
| SH3GL1 | -4200 |
| VPS37A | -4187 |
| XRCC5 | -4164 |
| RPL35A | -4159 |
| ITGB1 | -4145 |
| MAP2K1 | -4120 |
| GATAD2A | -4108 |
| PSMC5 | -4091 |
| RPL30 | -4081 |
| RPS9 | -4028 |
| GGT5 | -4012 |
| NR3C1 | -4005 |
| SLC25A5 | -4001 |
| RPL18 | -3961 |
| GNAI2 | -3904 |
| DYNC1LI2 | -3897 |
| SAP30L | -3887 |
| RPL26L1 | -3873 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| PARP16 | -3842 |
| PSME3 | -3813 |
| PLCG2 | -3766 |
| NELFCD | -3765 |
| NUP98 | -3764 |
| SLC25A6 | -3733 |
| GNAZ | -3724 |
| RBX1 | -3714 |
| GPHA2 | -3711 |
| POLR2B | -3699 |
| ATP1B2 | -3692 |
| GSK3A | -3684 |
| CD9 | -3660 |
| MVB12B | -3629 |
| DYNC1H1 | -3614 |
| TXN | -3611 |
| ROCK1 | -3594 |
| POLR2H | -3593 |
| MAN1B1 | -3561 |
| RPL28 | -3546 |
| RPSA | -3520 |
| NFKB1 | -3507 |
| MYO5A | -3500 |
| AP2A2 | -3499 |
| RCOR1 | -3493 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| POLR2C | -3425 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| WASF2 | -3366 |
| RPS24 | -3352 |
| SAP18 | -3349 |
| MAP2K3 | -3342 |
| MGAT2 | -3327 |
| RBBP4 | -3297 |
| RPS14 | -3261 |
| GNB1 | -3237 |
| SLC25A4 | -3203 |
| HMG20B | -3184 |
| RPS27L | -3180 |
| DPEP1 | -3163 |
| RPS10 | -3155 |
| SEM1 | -3130 |
| GTF2F1 | -3103 |
| TRIM28 | -3099 |
| RHBDF2 | -3089 |
| PSMA3 | -3078 |
| CUL3 | -3056 |
| GRB2 | -3047 |
| LYN | -3038 |
| RPS15A | -3019 |
| ELOB | -3004 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| WIPF2 | -2965 |
| TAF5 | -2960 |
| JUN | -2934 |
| PSMD8 | -2928 |
| RPS21 | -2927 |
| AP2S1 | -2922 |
| BECN1 | -2900 |
| RPS16 | -2898 |
| RIPK1 | -2886 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| FXYD1 | -2847 |
| ELOA | -2831 |
| SUPT4H1 | -2826 |
| ADCY6 | -2818 |
| HNRNPK | -2808 |
| NCKAP1 | -2788 |
| DYNC1I2 | -2780 |
| ELMO1 | -2779 |
| RPS27A | -2773 |
| ROCK2 | -2772 |
| JAK2 | -2719 |
| PSMA5 | -2715 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| HDAC1 | -2676 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RELA | -2632 |
| RPS13 | -2581 |
| PSMD13 | -2577 |
| RPL4 | -2563 |
| FNTB | -2551 |
| ADM | -2543 |
| B2M | -2523 |
| DYNC1LI1 | -2519 |
| GNAI1 | -2495 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| PSMC2 | -2389 |
| STX1A | -2377 |
| TLR9 | -2371 |
| MAP2K6 | -2351 |
| PSME1 | -2348 |
| IFNAR2 | -2313 |
| NELFB | -2298 |
| SUDS3 | -2287 |
| MOGS | -2275 |
| RPL39 | -2270 |
| DVL1 | -2264 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| ARPC2 | -2209 |
| CDC42 | -2172 |
| RCC1 | -2159 |
| NCBP1 | -2151 |
| TSG101 | -2130 |
| RPS4Y1 | -2120 |
| NFE2L2 | -2108 |
| NMT1 | -2085 |
| RPL27 | -2070 |
| PABPN1 | -2037 |
| NPM1 | -2033 |
| ERCC3 | -2013 |
| DBP | -2002 |
| CRBN | -1928 |
| NUP214 | -1926 |
| AP1G1 | -1916 |
| PSMB3 | -1915 |
| RPL23 | -1913 |
| SRPK2 | -1905 |
| AP2A1 | -1902 |
| UBAP1 | -1894 |
| XPO1 | -1864 |
| ST6GAL1 | -1828 |
| IMPDH1 | -1807 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| DUSP16 | -1750 |
| RPL26 | -1747 |
| CHMP5 | -1722 |
| ATP1A3 | -1706 |
| KPNA4 | -1701 |
| TBL1X | -1621 |
| PARP6 | -1567 |
| ARPC5 | -1511 |
| PSMC3 | -1509 |
| NDC1 | -1490 |
| ELL | -1439 |
| PRKACB | -1429 |
| YES1 | -1340 |
| CHD3 | -1321 |
| UBE2I | -1318 |
| RPL15 | -1313 |
| NFKB2 | -1311 |
| CUL5 | -1229 |
| TAF3 | -1222 |
| TUSC3 | -1219 |
| MYO1C | -1212 |
| SNF8 | -1198 |
| ABI2 | -1197 |
| RPL3 | -1165 |
| PSMB4 | -1144 |
| RPL17 | -1119 |
| GATAD2B | -1092 |
| CCNK | -1089 |
| CHMP2A | -1088 |
| PHF21A | -1078 |
| RPS8 | -1071 |
| MAN2A1 | -1040 |
| PRKAR1B | -1038 |
| HSP90AA1 | -1030 |
| TAF7 | -1012 |
| GNB3 | -1008 |
| RPL12 | -983 |
| NCKAP1L | -972 |
| RPS25 | -937 |
| VPS4B | -934 |
| SH3KBP1 | -917 |
| DVL2 | -905 |
| PSMA7 | -892 |
| CHMP2B | -878 |
| PRKAR2A | -860 |
| GALNT1 | -816 |
| PSMB5 | -742 |
| AP1S3 | -739 |
| RPL13 | -706 |
| MAPK8 | -700 |
| ADCY2 | -667 |
| CALM1 | -655 |
| BAIAP2 | -637 |
| POLR2J | -603 |
| REST | -593 |
| ERCC2 | -583 |
| PRKX | -553 |
| SKP1 | -544 |
| RPL5 | -495 |
| TAF9 | -483 |
| PSMD11 | -432 |
| TAF11 | -429 |
| GTF2H4 | -406 |
| HDAC2 | -338 |
| NUP160 | -329 |
| NUP62 | -299 |
| GGT1 | -250 |
| RPL22L1 | -214 |
| TAF2 | -206 |
| MNAT1 | -205 |
| RPS3A | -179 |
| ARID4A | -156 |
| RPS27 | -152 |
| PSMA6 | -126 |
| RANBP2 | -4 |
| PRKAR1A | 4 |
| NOXO1 | 10 |
| NELFE | 26 |
| XRCC6 | 28 |
| HDAC3 | 38 |
| RAC1 | 44 |
| STAT2 | 76 |
| ENTPD1 | 184 |
| KPNA5 | 258 |
| RPL9 | 261 |
| GTF2A1 | 328 |
| RPL31 | 330 |
| SUZ12 | 346 |
| FEN1 | 367 |
| ATP1A4 | 412 |
| PACS1 | 414 |
| RPS26 | 419 |
| PSMB10 | 423 |
| GNAS | 459 |
| PARP4 | 462 |
| RB1 | 470 |
| CREB1 | 474 |
| ARID4B | 480 |
| TPR | 565 |
| TAF10 | 626 |
| ELOC | 645 |
| GNB5 | 700 |
| SIGMAR1 | 753 |
| UBC | 779 |
| TAF1 | 788 |
| VPS37D | 809 |
| CHMP4A | 909 |
| AP1M2 | 914 |
| AP1B1 | 940 |
| ELMO2 | 942 |
| GPR39 | 994 |
| IFNGR2 | 997 |
| PML | 1051 |
| PSMB1 | 1054 |
| PIK3R4 | 1132 |
| TAF6 | 1145 |
| CHMP3 | 1229 |
| EPS15 | 1254 |
| RANBP1 | 1308 |
| GPR83 | 1350 |
| NUP133 | 1362 |
| RPL21 | 1385 |
| BTRC | 1386 |
| TBL1XR1 | 1404 |
| ACTR2 | 1435 |
| TMPRSS2 | 1456 |
| NCK1 | 1525 |
| CPSF4 | 1570 |
| IFNGR1 | 1624 |
| VTA1 | 1653 |
| SUGT1 | 1662 |
| MGAT4C | 1714 |
| PRKACA | 1736 |
| MTA1 | 1810 |
| HSPA1A | 1835 |
| STX1B | 1841 |
| PSMB2 | 1876 |
| NMT2 | 1894 |
| GNB4 | 1936 |
| FYN | 1937 |
| CYFIP1 | 1939 |
| POLR2G | 2003 |
| ABL1 | 2023 |
| AP2B1 | 2029 |
| IL18 | 2102 |
| RPL22 | 2142 |
| CYBA | 2202 |
| ITPR2 | 2257 |
| MAPK14 | 2269 |
| EED | 2369 |
| VPS4A | 2374 |
| NUP58 | 2380 |
| POLR2D | 2418 |
| MEFV | 2468 |
| VPS36 | 2474 |
| CYSLTR1 | 2493 |
| DYNLL1 | 2509 |
| PLCG1 | 2511 |
| COMT | 2597 |
| WASF3 | 2619 |
| CDK9 | 2631 |
| CHMP7 | 2690 |
| POLR2A | 2705 |
| NUP153 | 2712 |
| ACE2 | 2757 |
| NUP43 | 2808 |
| GANAB | 2813 |
| VAV2 | 2817 |
| RPL36A | 2875 |
| EIF2AK2 | 2886 |
| VPS25 | 2895 |
| AP1M1 | 2926 |
| AAAS | 2965 |
| SV2A | 2966 |
| PARP1 | 2974 |
| SRPK1 | 3007 |
| ARPC1A | 3022 |
| STAM2 | 3080 |
| SUPT16H | 3202 |
| PARP8 | 3263 |
| CTNNB1 | 3272 |
| SUMO1 | 3308 |
| NUP54 | 3310 |
| CORO1A | 3359 |
| XRCC4 | 3376 |
| RANGAP1 | 3458 |
| VAMP1 | 3484 |
| IRS1 | 3502 |
| DOCK1 | 3540 |
| GIPR | 3556 |
| DAXX | 3635 |
| PTGES3 | 3734 |
| BANF1 | 3790 |
| ARPC3 | 3797 |
| ENTPD5 | 3958 |
| SRC | 3962 |
| TBP | 3968 |
| VPS33B | 4043 |
| CCNT2 | 4117 |
| GNG5 | 4123 |
| VPS28 | 4152 |
| IFNAR1 | 4161 |
| NUP85 | 4178 |
| KDM1A | 4224 |
| ADCY9 | 4287 |
| PSMD12 | 4303 |
| GTF2H5 | 4373 |
| RAE1 | 4394 |
| GNG7 | 4426 |
| RNMT | 4440 |
| ANTXR1 | 4532 |
| GTF2F2 | 4556 |
| PSMD4 | 4567 |
| HMOX1 | 4592 |
| POLR2I | 4594 |
| DRD5 | 4609 |
| CBX1 | 4668 |
| ZCRB1 | 4731 |
| NUP155 | 4796 |
| ADCY1 | 4808 |
| AHCYL1 | 4874 |
| IMPDH2 | 4910 |
| PSMD10 | 4933 |
| PSMD7 | 4942 |
| TYK2 | 5066 |
| STAM | 5109 |
| PSMD5 | 5116 |
| TUBB | 5125 |
| ADORA2B | 5127 |
| RBBP7 | 5134 |
| GPR176 | 5289 |
| GTF2H2 | 5321 |
| ADORA2A | 5330 |
| PARP14 | 5386 |
| P2RX4 | 5401 |
| GSDMD | 5413 |
| GTF2A2 | 5445 |
| NCKIPSD | 5477 |
| FZD7 | 5487 |
| PSMB9 | 5491 |
| NOXA1 | 5500 |
| GTF2E1 | 5502 |
| CCNH | 5556 |
| RNF213 | 5584 |
| MVB12A | 5589 |
| HLA-A | 5777 |
| AP1S1 | 5804 |
| NUP93 | 5831 |
| PARP10 | 5859 |
| CHMP6 | 5904 |
| ST3GAL3 | 5918 |
| PSTPIP1 | 5948 |
| POLR2K | 5962 |
| PSMD14 | 5974 |
| NUP35 | 5982 |
| GTF2H3 | 6024 |
| DYNLL2 | 6044 |
| CD4 | 6074 |
| NUP107 | 6076 |
| TAF9B | 6106 |
| CASP1 | 6109 |
| GNG4 | 6164 |
| LIG1 | 6206 |
| CYFIP2 | 6224 |
| RAMP2 | 6288 |
| ADCY7 | 6316 |
| MTA3 | 6411 |
| LIG4 | 6454 |
| IL1R1 | 6510 |
| TAF12 | 6601 |
| DUT | 6636 |
| MAPK3 | 6640 |
| GNG10 | 6779 |
| NUP210 | 6802 |
| NCBP2 | 6823 |
| CEBPD | 6867 |
| PYCARD | 6900 |
| PARP9 | 6988 |
| TAF15 | 7061 |
| APOBEC3G | 7066 |
| MC1R | 7078 |
| NUP37 | 7100 |
| CTNND1 | 7129 |
| PSIP1 | 7193 |
| NEDD4L | 7233 |
| CDH1 | 7296 |
| JAK3 | 7326 |
| C3 | 7357 |
| TXNIP | 7384 |
SRP-dependent cotranslational protein targeting to membrane
| 1038 | |
|---|---|
| set | SRP-dependent cotranslational protein targeting to membrane |
| setSize | 109 |
| pANOVA | 1.48e-17 |
| s.dist | -0.473 |
| p.adjustANOVA | 5.09e-15 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SEC61A1 | -7030 |
| RPN1 | -7013 |
| SSR4 | -7004 |
| TRAM1 | -6997 |
| SEC11C | -6991 |
| RPL36AL | -6981 |
| SEC61B | -6958 |
| SSR3 | -6928 |
| SSR1 | -6907 |
| SRPRB | -6893 |
| SPCS3 | -6781 |
| SSR2 | -6759 |
| DDOST | -6429 |
| SRP68 | -6420 |
| SRP19 | -6363 |
| RPN2 | -6193 |
| SRP14 | -5938 |
| SPCS2 | -5930 |
| SRP72 | -5526 |
| RPL19 | -5254 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SEC61A1 | -7030 |
| RPN1 | -7013 |
| SSR4 | -7004 |
| TRAM1 | -6997 |
| SEC11C | -6991 |
| RPL36AL | -6981 |
| SEC61B | -6958 |
| SSR3 | -6928 |
| SSR1 | -6907 |
| SRPRB | -6893 |
| SPCS3 | -6781 |
| SSR2 | -6759 |
| DDOST | -6429 |
| SRP68 | -6420 |
| SRP19 | -6363 |
| RPN2 | -6193 |
| SRP14 | -5938 |
| SPCS2 | -5930 |
| SRP72 | -5526 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| SRPRA | -4802 |
| RPS5 | -4778 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| RPL30 | -4081 |
| SEC61G | -4052 |
| RPS9 | -4028 |
| RPL18 | -3961 |
| RPL26L1 | -3873 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| RPL28 | -3546 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| SEC11A | -3046 |
| RPS15A | -3019 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| RPS27A | -2773 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| SRP54 | -1969 |
| RPL23 | -1913 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| SEC61A2 | -1397 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| RPS25 | -937 |
| RPL13 | -706 |
| RPL5 | -495 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPS26 | 419 |
| RPL21 | 1385 |
| RPL22 | 2142 |
| SPCS1 | 2416 |
| RPL36A | 2875 |
| SRP9 | 5604 |
Asparagine N-linked glycosylation
| 74 | |
|---|---|
| set | Asparagine N-linked glycosylation |
| setSize | 252 |
| pANOVA | 6.7e-17 |
| s.dist | -0.306 |
| p.adjustANOVA | 1.85e-14 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CALR | -7142 |
| SEC24D | -7134 |
| SEL1L | -7124 |
| SYVN1 | -7108 |
| EDEM1 | -7103 |
| CANX | -7092 |
| PDIA3 | -7086 |
| SLC17A5 | -7072 |
| TMED2 | -7071 |
| MCFD2 | -7065 |
| GFPT1 | -7051 |
| MIA3 | -7049 |
| DERL2 | -7046 |
| MAGT1 | -7045 |
| RPN1 | -7013 |
| FUT3 | -7001 |
| OS9 | -6986 |
| UGGT1 | -6954 |
| TMED7 | -6933 |
| NANS | -6906 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CALR | -7142 |
| SEC24D | -7134 |
| SEL1L | -7124 |
| SYVN1 | -7108 |
| EDEM1 | -7103 |
| CANX | -7092 |
| PDIA3 | -7086 |
| SLC17A5 | -7072 |
| TMED2 | -7071 |
| MCFD2 | -7065 |
| GFPT1 | -7051 |
| MIA3 | -7049 |
| DERL2 | -7046 |
| MAGT1 | -7045 |
| RPN1 | -7013 |
| FUT3 | -7001 |
| OS9 | -6986 |
| UGGT1 | -6954 |
| TMED7 | -6933 |
| NANS | -6906 |
| MLEC | -6902 |
| GMPPB | -6844 |
| SEC24A | -6839 |
| SEC13 | -6812 |
| ST3GAL4 | -6801 |
| STT3A | -6796 |
| ANK2 | -6778 |
| TMEM115 | -6764 |
| NEU1 | -6752 |
| ST6GALNAC4 | -6726 |
| VCP | -6720 |
| SLC35C1 | -6667 |
| RNF5 | -6629 |
| ALG3 | -6601 |
| TRAPPC10 | -6585 |
| LMAN2 | -6558 |
| ALG2 | -6554 |
| COPB2 | -6532 |
| CD55 | -6517 |
| PPP6R1 | -6511 |
| ARCN1 | -6505 |
| TMED9 | -6502 |
| ALG5 | -6471 |
| MAN1A2 | -6460 |
| DDOST | -6429 |
| DERL1 | -6423 |
| MGAT1 | -6401 |
| NUS1 | -6395 |
| RNF185 | -6359 |
| GMPPA | -6346 |
| CTSA | -6288 |
| MGAT4B | -6279 |
| DAD1 | -6240 |
| SEC24C | -6236 |
| TBC1D20 | -6203 |
| RPN2 | -6193 |
| RNF103 | -6135 |
| TMED10 | -6116 |
| ALG12 | -6081 |
| DPAGT1 | -6046 |
| ARF1 | -6021 |
| SEC16A | -5971 |
| COPE | -5961 |
| ALG11 | -5957 |
| COG3 | -5948 |
| PRKCSH | -5934 |
| NAPA | -5921 |
| ST3GAL1 | -5905 |
| KDELR2 | -5893 |
| MGAT5 | -5854 |
| ARF4 | -5812 |
| SEC31A | -5766 |
| RENBP | -5761 |
| CSNK1D | -5722 |
| PSMC1 | -5564 |
| EDEM2 | -5520 |
| SEC24B | -5475 |
| UBXN1 | -5450 |
| PGM3 | -5395 |
| TFG | -5336 |
| GOLGA2 | -5310 |
| STX5 | -5300 |
| PPP6C | -5241 |
| PMM2 | -5187 |
| ACTR1A | -5162 |
| COPG1 | -5135 |
| FUT8 | -5134 |
| KDELR1 | -5094 |
| UBA52 | -5068 |
| MGAT4A | -5018 |
| DOLPP1 | -4988 |
| GBF1 | -4981 |
| SPTBN1 | -4901 |
| YKT6 | -4899 |
| CAPZA1 | -4855 |
| B4GALT3 | -4852 |
| AREG | -4847 |
| NSF | -4839 |
| ST6GALNAC6 | -4820 |
| ARFGAP3 | -4817 |
| ANK1 | -4656 |
| TRAPPC2L | -4576 |
| ST3GAL2 | -4518 |
| TGFA | -4511 |
| CTSC | -4446 |
| ALG1 | -4352 |
| UBB | -4263 |
| COG2 | -4254 |
| NUDT14 | -4170 |
| COPB1 | -4098 |
| TMED3 | -4057 |
| TRAPPC3 | -4032 |
| COG5 | -3964 |
| COPA | -3958 |
| DCTN2 | -3957 |
| DYNC1LI2 | -3897 |
| NAPG | -3872 |
| DCTN5 | -3634 |
| DYNC1H1 | -3614 |
| MAN1B1 | -3561 |
| USO1 | -3509 |
| GOLGB1 | -3498 |
| RAB1B | -3479 |
| LMAN1 | -3431 |
| LMAN2L | -3429 |
| GMDS | -3350 |
| MGAT2 | -3327 |
| RAB1A | -3307 |
| ST3GAL6 | -3252 |
| CD59 | -3245 |
| ALG14 | -3206 |
| RNF139 | -3064 |
| ASGR2 | -2985 |
| SAR1B | -2973 |
| NGLY1 | -2909 |
| DYNC1I2 | -2780 |
| RPS27A | -2773 |
| SEC23A | -2717 |
| AMFR | -2698 |
| PMM1 | -2658 |
| DYNC1LI1 | -2519 |
| B4GALT2 | -2487 |
| ARF3 | -2430 |
| MAN2A2 | -2336 |
| MOGS | -2275 |
| DPM2 | -2111 |
| CNIH3 | -1958 |
| DCTN4 | -1937 |
| EDEM3 | -1903 |
| ASGR1 | -1889 |
| ST6GAL1 | -1828 |
| ST8SIA5 | -1758 |
| SEC22C | -1684 |
| DCTN1 | -1635 |
| ARFGAP1 | -1587 |
| CAPZA2 | -1549 |
| DPM1 | -1233 |
| TUSC3 | -1219 |
| CAPZB | -1169 |
| MAN2A1 | -1040 |
| MAN1A1 | -1021 |
| UAP1 | -898 |
| PPP6R3 | -623 |
| ALG9 | -426 |
| NAPB | -419 |
| DCTN6 | -318 |
| B4GALT1 | -262 |
| DOLK | 108 |
| CNIH1 | 212 |
| TRAPPC5 | 239 |
| ANK3 | 303 |
| SEC23IP | 390 |
| BET1 | 457 |
| NANP | 483 |
| SCFD1 | 485 |
| GOSR1 | 621 |
| F8 | 735 |
| UBC | 779 |
| COPZ1 | 782 |
| F5 | 831 |
| SEC22B | 859 |
| KDELR3 | 976 |
| ALG8 | 1117 |
| GOSR2 | 1238 |
| ARFGAP2 | 1283 |
| ALG13 | 1348 |
| B4GALNT2 | 1387 |
| UGGT2 | 1425 |
| PREB | 1446 |
| DCTN3 | 1457 |
| GLB1 | 1557 |
| MGAT4C | 1714 |
| TRAPPC4 | 1781 |
| TRIM13 | 1883 |
| GORASP1 | 1903 |
| COG4 | 1972 |
| ST8SIA1 | 2289 |
| SPTAN1 | 2385 |
| GNPNAT1 | 2394 |
| DHDDS | 2399 |
| DYNLL1 | 2509 |
| FUOM | 2573 |
| TRAPPC6B | 2584 |
| STX17 | 2586 |
| B4GALT4 | 2602 |
| ALG10 | 2654 |
| FUCA1 | 2696 |
| GANAB | 2813 |
| B4GALT6 | 2881 |
| MAN1C1 | 3072 |
| TRAPPC1 | 3089 |
| RAD23B | 3141 |
| DPM3 | 3217 |
| COG6 | 3264 |
| SEC22A | 3312 |
| BET1L | 3487 |
| TRAPPC2 | 3547 |
| MPDU1 | 3718 |
| SPTBN2 | 3883 |
| SLC35A1 | 3906 |
| SERPINA1 | 4014 |
| ANKRD28 | 4146 |
| MANEA | 4202 |
| NAGK | 4508 |
| COG1 | 4586 |
| ARF5 | 4743 |
| SRD5A3 | 4758 |
| COG7 | 4792 |
| ALG6 | 4943 |
| TRAPPC9 | 5033 |
| MPI | 5076 |
| RFT1 | 5083 |
| ST3GAL5 | 5090 |
| COL7A1 | 5362 |
| AMDHD2 | 5414 |
| ACTR10 | 5570 |
| FPGT | 5627 |
| CMAS | 5724 |
| ALG10B | 5899 |
| ST3GAL3 | 5918 |
| DYNLL2 | 6044 |
| GNE | 6051 |
| COPG2 | 6142 |
| ENGASE | 6457 |
| SEC16B | 6744 |
| COG8 | 6745 |
| B4GALT5 | 6846 |
| CHST10 | 6919 |
| NEU4 | 6950 |
| NEU3 | 7085 |
| TRAPPC6A | 7244 |
| MVD | 7302 |
Axon guidance
| 87 | |
|---|---|
| set | Axon guidance |
| setSize | 424 |
| pANOVA | 2.94e-16 |
| s.dist | -0.232 |
| p.adjustANOVA | 6.75e-14 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| VASP | -7075 |
| ABLIM1 | -7055 |
| RPL36AL | -6981 |
| ETF1 | -6952 |
| RNPS1 | -6938 |
| ARHGEF28 | -6925 |
| SHC1 | -6910 |
| MET | -6878 |
| RANBP9 | -6871 |
| EPHA2 | -6857 |
| ACTG1 | -6841 |
| GSPT1 | -6825 |
| ANK2 | -6778 |
| SEMA6A | -6761 |
| RHOC | -6747 |
| SCN2A | -6712 |
| SIAH2 | -6666 |
| PSMF1 | -6663 |
| MYL12B | -6653 |
| WASL | -6543 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| VASP | -7075 |
| ABLIM1 | -7055 |
| RPL36AL | -6981 |
| ETF1 | -6952 |
| RNPS1 | -6938 |
| ARHGEF28 | -6925 |
| SHC1 | -6910 |
| MET | -6878 |
| RANBP9 | -6871 |
| EPHA2 | -6857 |
| ACTG1 | -6841 |
| GSPT1 | -6825 |
| ANK2 | -6778 |
| SEMA6A | -6761 |
| RHOC | -6747 |
| SCN2A | -6712 |
| SIAH2 | -6666 |
| PSMF1 | -6663 |
| MYL12B | -6653 |
| WASL | -6543 |
| DNM2 | -6535 |
| DPYSL2 | -6519 |
| ITGA10 | -6466 |
| PSME4 | -6450 |
| ARHGAP35 | -6446 |
| CLTA | -6439 |
| PSMD2 | -6435 |
| MYL6 | -6380 |
| PLXNA3 | -6318 |
| ARHGAP39 | -6303 |
| PFN1 | -6285 |
| UNC5B | -6252 |
| CLTC | -6220 |
| ITGA2 | -6205 |
| FGFR1 | -6191 |
| UPF3A | -6189 |
| TLN1 | -6146 |
| PRNP | -6115 |
| ARPC4 | -6094 |
| MAP2K2 | -6087 |
| CLTB | -6064 |
| CASC3 | -5986 |
| PSMD6 | -5951 |
| MYO9B | -5920 |
| EIF4G1 | -5901 |
| EFNA1 | -5830 |
| PSMA2 | -5801 |
| CFL1 | -5737 |
| PSMA1 | -5730 |
| PLXND1 | -5686 |
| CACNA1D | -5676 |
| PITPNA | -5591 |
| GIT1 | -5582 |
| ROBO1 | -5577 |
| PSMC1 | -5564 |
| HRAS | -5543 |
| MAPK12 | -5538 |
| PSMD3 | -5535 |
| GRB10 | -5504 |
| PSME2 | -5481 |
| IRS2 | -5461 |
| SOS2 | -5417 |
| EGFR | -5383 |
| PAK4 | -5359 |
| PSMD1 | -5351 |
| TRIO | -5341 |
| NRP2 | -5313 |
| ACTR3 | -5296 |
| RHOA | -5294 |
| MYO10 | -5290 |
| ZSWIM8 | -5267 |
| ARHGEF11 | -5260 |
| RPL19 | -5254 |
| NUMB | -5224 |
| PSPN | -5177 |
| EPHB1 | -5141 |
| RPS7 | -5138 |
| GSK3B | -5101 |
| UBA52 | -5068 |
| MAPK1 | -5066 |
| ACTB | -5057 |
| CSNK2A1 | -5040 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| RAP1GAP | -4998 |
| FAU | -4990 |
| RPL14 | -4978 |
| PAK2 | -4957 |
| PSEN1 | -4938 |
| SPTBN1 | -4901 |
| PSMB6 | -4888 |
| PSMC6 | -4878 |
| PSMC4 | -4808 |
| RPS5 | -4778 |
| PIK3CD | -4759 |
| MYH9 | -4726 |
| RPS11 | -4702 |
| MMP2 | -4677 |
| RPS19 | -4661 |
| ANK1 | -4656 |
| HSPA8 | -4654 |
| RPS28 | -4652 |
| VAV3 | -4642 |
| PSMD9 | -4638 |
| AP2M1 | -4603 |
| CSNK2A2 | -4546 |
| EZR | -4464 |
| ARPC1B | -4429 |
| HSP90AB1 | -4426 |
| RPLP1 | -4391 |
| MAPK7 | -4382 |
| EPHB4 | -4379 |
| PIK3R1 | -4376 |
| PSMB7 | -4372 |
| RPS12 | -4367 |
| PTK2 | -4346 |
| ITGAV | -4312 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| UBB | -4263 |
| CLASP2 | -4246 |
| PSMA4 | -4211 |
| RPL35A | -4159 |
| ITGB1 | -4145 |
| GAB2 | -4127 |
| MAP2K1 | -4120 |
| LYPLA2 | -4095 |
| PSMC5 | -4091 |
| CAP1 | -4085 |
| RPL30 | -4081 |
| PPP3CB | -4060 |
| RPS9 | -4028 |
| GRB7 | -4006 |
| GDNF | -3969 |
| RPL18 | -3961 |
| NCK2 | -3916 |
| CACNA1H | -3915 |
| RPL26L1 | -3873 |
| DLG1 | -3865 |
| RPS6KA1 | -3857 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| UPF2 | -3830 |
| NRCAM | -3815 |
| PLXNA2 | -3814 |
| PSME3 | -3813 |
| FRS2 | -3790 |
| SHC3 | -3782 |
| PLXNB3 | -3778 |
| RBX1 | -3714 |
| ROCK1 | -3594 |
| RPL28 | -3546 |
| PABPC1 | -3543 |
| RPSA | -3520 |
| AP2A2 | -3499 |
| EFNB2 | -3470 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| MYL12A | -3398 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| SIAH1 | -3347 |
| SEMA7A | -3299 |
| RPS14 | -3261 |
| PIP5K1C | -3229 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| ENAH | -3139 |
| SEM1 | -3130 |
| PSMA3 | -3078 |
| GRB2 | -3047 |
| LYN | -3038 |
| RPS6KA3 | -3030 |
| ABL2 | -3020 |
| RPS15A | -3019 |
| ELOB | -3004 |
| DOK6 | -2987 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| PSMD8 | -2928 |
| RPS21 | -2927 |
| AP2S1 | -2922 |
| ARHGEF7 | -2913 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| DSCAML1 | -2830 |
| PIK3CA | -2813 |
| RPS27A | -2773 |
| ROCK2 | -2772 |
| PSMA5 | -2715 |
| DOK4 | -2697 |
| CAP2 | -2694 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| ADAM10 | -2671 |
| RPS18 | -2648 |
| PDLIM7 | -2636 |
| RPL41 | -2635 |
| PIK3CB | -2588 |
| RPS13 | -2581 |
| PSMD13 | -2577 |
| RPL4 | -2563 |
| PSEN2 | -2559 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| PSMC2 | -2389 |
| AGRN | -2369 |
| PSME1 | -2348 |
| PSENEN | -2327 |
| PIK3R3 | -2279 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| ARPC2 | -2209 |
| DAG1 | -2174 |
| CDC42 | -2172 |
| NCBP1 | -2151 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| KRAS | -2044 |
| NTN4 | -1999 |
| PSMB3 | -1915 |
| RPL23 | -1913 |
| AP2A1 | -1902 |
| MAPK13 | -1875 |
| SDCBP | -1822 |
| RPL24 | -1804 |
| SRGAP1 | -1796 |
| RPL38 | -1791 |
| SRGAP2 | -1779 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| RBM8A | -1583 |
| RRAS | -1578 |
| ARPC5 | -1511 |
| PSMC3 | -1509 |
| PRKACB | -1429 |
| RND1 | -1410 |
| PIK3R2 | -1355 |
| CDK5 | -1352 |
| YES1 | -1340 |
| RPL15 | -1313 |
| LAMC1 | -1300 |
| EFNA3 | -1228 |
| RPL3 | -1165 |
| RPS6KA2 | -1149 |
| PSMB4 | -1144 |
| RPL17 | -1119 |
| ARHGEF12 | -1086 |
| RPS8 | -1071 |
| PLXNA1 | -1050 |
| PLXNB1 | -1046 |
| HSP90AA1 | -1030 |
| RPL12 | -983 |
| MAGOH | -969 |
| SOS1 | -950 |
| RPS25 | -937 |
| SH3KBP1 | -917 |
| L1CAM | -904 |
| PSMA7 | -892 |
| PTPN11 | -867 |
| PRKAR2A | -860 |
| PSMB5 | -742 |
| RPL13 | -706 |
| MAPK8 | -700 |
| ITGA2B | -688 |
| RELN | -662 |
| NCSTN | -554 |
| RPL5 | -495 |
| GRIN1 | -442 |
| PSMD11 | -432 |
| KALRN | -408 |
| SCN11A | -295 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| CDK5R1 | -157 |
| RPS27 | -152 |
| PSMA6 | -126 |
| RAC1 | 44 |
| SDC2 | 147 |
| ITSN1 | 159 |
| CNTN2 | 200 |
| SCN8A | 249 |
| MAPK11 | 251 |
| RPL9 | 261 |
| ANK3 | 303 |
| RPL31 | 330 |
| CUL2 | 359 |
| RPS26 | 419 |
| PSMB10 | 423 |
| CREB1 | 474 |
| SHTN1 | 547 |
| ITGA5 | 587 |
| APH1A | 619 |
| ELOC | 645 |
| RPS6KA4 | 731 |
| UBC | 779 |
| PTPRA | 815 |
| SLIT1 | 886 |
| SHANK3 | 935 |
| ARTN | 973 |
| RDX | 1011 |
| MYH11 | 1015 |
| PAK1 | 1031 |
| PSMB1 | 1054 |
| EIF4A3 | 1154 |
| LAMA1 | 1285 |
| RGMB | 1321 |
| GRIN2B | 1330 |
| NRP1 | 1353 |
| RPL21 | 1385 |
| ACTR2 | 1435 |
| NCK1 | 1525 |
| DPYSL4 | 1531 |
| CLASP1 | 1561 |
| LIMK1 | 1565 |
| GAB1 | 1575 |
| EPHA10 | 1725 |
| EFNA2 | 1735 |
| PRKACA | 1736 |
| PSMB2 | 1876 |
| LDB1 | 1882 |
| USP33 | 1924 |
| FYN | 1937 |
| CACNB4 | 1983 |
| ABL1 | 2023 |
| AP2B1 | 2029 |
| COL6A3 | 2085 |
| RPL22 | 2142 |
| MAPK14 | 2269 |
| NRAS | 2310 |
| UPF3B | 2326 |
| SPTAN1 | 2385 |
| SCN1B | 2398 |
| PRKCA | 2439 |
| EVL | 2467 |
| SCN3B | 2499 |
| PLCG1 | 2511 |
| MYH10 | 2558 |
| RASA1 | 2559 |
| ABLIM3 | 2675 |
| MYL9 | 2704 |
| HOXA2 | 2735 |
| VAV2 | 2817 |
| RPL36A | 2875 |
| CACNB1 | 2967 |
| VLDLR | 3001 |
| ARPC1A | 3022 |
| AKAP5 | 3035 |
| RPS6KA5 | 3086 |
| ALCAM | 3171 |
| RGMA | 3210 |
| COL6A2 | 3222 |
| EFNB3 | 3419 |
| EFNB1 | 3480 |
| SCN9A | 3533 |
| DOCK1 | 3540 |
| TRPC1 | 3602 |
| EFNA4 | 3658 |
| FARP2 | 3688 |
| CACNB3 | 3735 |
| LAMB1 | 3783 |
| ARPC3 | 3797 |
| NRTN | 3870 |
| SPTBN2 | 3883 |
| RPS6KA6 | 3918 |
| SRC | 3962 |
| SEMA3A | 4001 |
| NEO1 | 4016 |
| DOK1 | 4072 |
| PSMD12 | 4303 |
| PLXNC1 | 4319 |
| MSI1 | 4326 |
| GFRA3 | 4393 |
| AGAP2 | 4399 |
| CSNK2B | 4415 |
| TIAM1 | 4452 |
| PSMD4 | 4567 |
| ROBO3 | 4691 |
| PSMD10 | 4933 |
| PSMD7 | 4942 |
| EPHA1 | 4960 |
| DLG4 | 5108 |
| PSMD5 | 5116 |
| ITGA1 | 5152 |
| DLG3 | 5168 |
| GPC1 | 5178 |
| CD24 | 5327 |
| PSMB9 | 5491 |
| MYH14 | 5492 |
| FES | 5506 |
| ERBB2 | 5534 |
| MAGOHB | 5814 |
| PSMD14 | 5974 |
| KIF4A | 6056 |
| RHOB | 6064 |
| APH1B | 6168 |
| ABLIM2 | 6389 |
| LIMK2 | 6394 |
| CLTCL1 | 6404 |
| SEMA4D | 6479 |
| DNM1 | 6505 |
| MAPK3 | 6640 |
| COL4A5 | 6694 |
| SRGAP3 | 6775 |
| NCBP2 | 6823 |
| PFN2 | 6877 |
| NGEF | 7064 |
| COL9A3 | 7151 |
| FLRT3 | 7184 |
| CNTNAP1 | 7239 |
| COL6A1 | 7322 |
| SCN1A | 7327 |
| COL9A2 | 7348 |
Cellular response to starvation
| 154 | |
|---|---|
| set | Cellular response to starvation |
| setSize | 149 |
| pANOVA | 2.02e-14 |
| s.dist | -0.363 |
| p.adjustANOVA | 3.98e-12 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| ATP6V0B | -7064 |
| DDIT3 | -7047 |
| FLCN | -7022 |
| RRAGC | -7009 |
| RPL36AL | -6981 |
| ATP6V1D | -6922 |
| ATP6V0D1 | -6908 |
| SEC13 | -6812 |
| TRIB3 | -6798 |
| FNIP1 | -6782 |
| RRAGD | -6743 |
| ATP6V0E1 | -6622 |
| SESN2 | -6610 |
| ATP6V1E1 | -6271 |
| ATF2 | -6175 |
| ATP6V0C | -6086 |
| CEBPG | -5987 |
| ATP6V1C2 | -5929 |
| ATF4 | -5664 |
| ATP6V1B2 | -5574 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ATP6V0B | -7064 |
| DDIT3 | -7047 |
| FLCN | -7022 |
| RRAGC | -7009 |
| RPL36AL | -6981 |
| ATP6V1D | -6922 |
| ATP6V0D1 | -6908 |
| SEC13 | -6812 |
| TRIB3 | -6798 |
| FNIP1 | -6782 |
| RRAGD | -6743 |
| ATP6V0E1 | -6622 |
| SESN2 | -6610 |
| ATP6V1E1 | -6271 |
| ATF2 | -6175 |
| ATP6V0C | -6086 |
| CEBPG | -5987 |
| ATP6V1C2 | -5929 |
| ATF4 | -5664 |
| ATP6V1B2 | -5574 |
| SLC38A9 | -5539 |
| FNIP2 | -5498 |
| ATP6V1G1 | -5352 |
| LAMTOR5 | -5293 |
| RPL19 | -5254 |
| EIF2S1 | -5190 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| DEPDC5 | -4989 |
| RPL14 | -4978 |
| ATP6V1C1 | -4946 |
| RRAGB | -4819 |
| RPS5 | -4778 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| GCN1 | -4627 |
| SEH1L | -4472 |
| EIF2S2 | -4458 |
| ATP6V1H | -4423 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| RPL30 | -4081 |
| RPS9 | -4028 |
| RPL18 | -3961 |
| RPL26L1 | -3873 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| ATP6V1A | -3777 |
| RHEB | -3762 |
| MTOR | -3683 |
| EIF2S3 | -3669 |
| RPL28 | -3546 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| SH3BP4 | -3331 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| RPS15A | -3019 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| RPS27A | -2773 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| LAMTOR3 | -2631 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| RPL23 | -1913 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| EIF2AK4 | -1455 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| CEBPB | -1129 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| RPS25 | -937 |
| ATP6V1F | -868 |
| LAMTOR1 | -774 |
| RPL13 | -706 |
| ATP6V1E2 | -534 |
| RPL5 | -495 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| LAMTOR2 | -148 |
| TCIRG1 | 180 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPTOR | 407 |
| RPS26 | 419 |
| BMT2 | 638 |
| ATP6V1G2 | 690 |
| ATP6V0D2 | 747 |
| RPL21 | 1385 |
| LAMTOR4 | 1834 |
| MLST8 | 1875 |
| RPL22 | 2142 |
| ITFG2 | 2143 |
| ATF3 | 2488 |
| RRAGA | 2609 |
| RPL36A | 2875 |
| MIOS | 2912 |
| NPRL3 | 4164 |
| IMPACT | 4432 |
| WDR24 | 4466 |
| KPTN | 4478 |
| ATP6V1B1 | 4549 |
| NPRL2 | 4876 |
| WDR59 | 4915 |
| SESN1 | 4963 |
| SZT2 | 5052 |
| ATP6V0E2 | 5683 |
| ASNS | 6208 |
Metabolism of proteins
| 630 | |
|---|---|
| set | Metabolism of proteins |
| setSize | 1550 |
| pANOVA | 3.25e-14 |
| s.dist | -0.118 |
| p.adjustANOVA | 5.59e-12 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CALR | -7142 |
| RAB17 | -7135 |
| SEC24D | -7134 |
| DNAJC3 | -7131 |
| HSP90B1 | -7129 |
| SEL1L | -7124 |
| SELENOS | -7117 |
| SYVN1 | -7108 |
| PDIA6 | -7106 |
| EDEM1 | -7103 |
| WFS1 | -7096 |
| KLF4 | -7093 |
| CANX | -7092 |
| PDIA3 | -7086 |
| ERO1B | -7079 |
| SLC17A5 | -7072 |
| TMED2 | -7071 |
| KLHL21 | -7069 |
| MCFD2 | -7065 |
| ARRB1 | -7062 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CALR | -7142 |
| RAB17 | -7135 |
| SEC24D | -7134 |
| DNAJC3 | -7131 |
| HSP90B1 | -7129 |
| SEL1L | -7124 |
| SELENOS | -7117 |
| SYVN1 | -7108 |
| PDIA6 | -7106 |
| EDEM1 | -7103 |
| WFS1 | -7096 |
| KLF4 | -7093 |
| CANX | -7092 |
| PDIA3 | -7086 |
| ERO1B | -7079 |
| SLC17A5 | -7072 |
| TMED2 | -7071 |
| KLHL21 | -7069 |
| MCFD2 | -7065 |
| ARRB1 | -7062 |
| GCNT3 | -7052 |
| GFPT1 | -7051 |
| MIA3 | -7049 |
| DERL2 | -7046 |
| MAGT1 | -7045 |
| SEC61A1 | -7030 |
| WSB2 | -7029 |
| RPN1 | -7013 |
| SSR4 | -7004 |
| FUT3 | -7001 |
| TRAM1 | -6997 |
| EIF4A1 | -6995 |
| SEC11C | -6991 |
| OS9 | -6986 |
| RPL36AL | -6981 |
| EIF3A | -6965 |
| ASB2 | -6960 |
| SEC61B | -6958 |
| UGGT1 | -6954 |
| ETF1 | -6952 |
| ARSB | -6939 |
| TGFB1 | -6934 |
| TMED7 | -6933 |
| SSR3 | -6928 |
| SSR1 | -6907 |
| NANS | -6906 |
| MLEC | -6902 |
| SRPRB | -6893 |
| P4HB | -6884 |
| BMP4 | -6869 |
| VGF | -6864 |
| GMPPB | -6844 |
| SEC24A | -6839 |
| GSPT1 | -6825 |
| SLC30A7 | -6817 |
| SEC13 | -6812 |
| ST3GAL4 | -6801 |
| STT3A | -6796 |
| POMT2 | -6788 |
| SPCS3 | -6781 |
| ANK2 | -6778 |
| TMEM115 | -6764 |
| SSR2 | -6759 |
| NEU1 | -6752 |
| MBD6 | -6742 |
| ST6GALNAC4 | -6726 |
| PPARA | -6722 |
| VCP | -6720 |
| CSF1 | -6711 |
| RAB43 | -6699 |
| FURIN | -6683 |
| DPP4 | -6681 |
| GBA | -6674 |
| SLC35C1 | -6667 |
| SIAH2 | -6666 |
| DDX5 | -6665 |
| PSMF1 | -6663 |
| LGALS1 | -6649 |
| SOCS5 | -6643 |
| KIF5A | -6634 |
| RNF5 | -6629 |
| UIMC1 | -6627 |
| RAB20 | -6619 |
| ALG3 | -6601 |
| SERPINC1 | -6588 |
| TRAPPC10 | -6585 |
| FOXK2 | -6570 |
| LMAN2 | -6558 |
| ALG2 | -6554 |
| USP16 | -6545 |
| FUCA2 | -6538 |
| COPB2 | -6532 |
| RAB22A | -6525 |
| CD55 | -6517 |
| PPP6R1 | -6511 |
| ARCN1 | -6505 |
| TMED9 | -6502 |
| APP | -6492 |
| VHL | -6491 |
| KEAP1 | -6482 |
| TOP1 | -6472 |
| ALG5 | -6471 |
| EP300 | -6470 |
| MAN1A2 | -6460 |
| PSME4 | -6450 |
| NFKBIA | -6437 |
| PSMD2 | -6435 |
| ADRA2C | -6434 |
| DDOST | -6429 |
| DERL1 | -6423 |
| SRP68 | -6420 |
| SPON2 | -6404 |
| MGAT1 | -6401 |
| MTRF1L | -6400 |
| NUS1 | -6395 |
| GATA4 | -6369 |
| SRP19 | -6363 |
| RNF185 | -6359 |
| THSD4 | -6356 |
| POM121 | -6353 |
| GMPPA | -6346 |
| APOA2 | -6307 |
| TIMP1 | -6294 |
| CTSA | -6288 |
| MGAT4B | -6279 |
| RARA | -6269 |
| CCT5 | -6251 |
| DAD1 | -6240 |
| KIFC3 | -6237 |
| SEC24C | -6236 |
| TTLL11 | -6233 |
| UBE2J2 | -6232 |
| STC2 | -6224 |
| TECTB | -6219 |
| TBC1D20 | -6203 |
| RPN2 | -6193 |
| PIGG | -6186 |
| SAFB | -6184 |
| SMAD3 | -6145 |
| DCAF11 | -6142 |
| YOD1 | -6141 |
| GGA2 | -6138 |
| RNF103 | -6135 |
| LONP2 | -6122 |
| TMED10 | -6116 |
| ALG12 | -6081 |
| CYLD | -6066 |
| EIF5 | -6065 |
| HCFC1 | -6060 |
| DPAGT1 | -6046 |
| POM121C | -6045 |
| NR1H4 | -6037 |
| ARF1 | -6021 |
| RAB9A | -6014 |
| JOSD1 | -5993 |
| SEC16A | -5971 |
| WAC | -5965 |
| COPE | -5961 |
| MBTPS1 | -5958 |
| ALG11 | -5957 |
| PSMD6 | -5951 |
| COG3 | -5948 |
| IKBKG | -5946 |
| FBXW5 | -5945 |
| OTUD5 | -5944 |
| SRP14 | -5938 |
| PRKCSH | -5934 |
| SPCS2 | -5930 |
| CCT2 | -5926 |
| NAPA | -5921 |
| GNA11 | -5916 |
| ST3GAL1 | -5905 |
| EIF4G1 | -5901 |
| EIF4B | -5898 |
| ZRANB1 | -5895 |
| KDELR2 | -5893 |
| MUL1 | -5892 |
| UBE2F | -5885 |
| SIN3A | -5884 |
| PCGF2 | -5881 |
| RORA | -5875 |
| SPP1 | -5872 |
| PPARGC1A | -5869 |
| CCT6A | -5862 |
| MGAT5 | -5854 |
| ASXL2 | -5845 |
| DCUN1D3 | -5821 |
| ARF4 | -5812 |
| RAB7A | -5810 |
| PSMA2 | -5801 |
| RIPK2 | -5779 |
| SEC31A | -5766 |
| UBE2G1 | -5763 |
| RENBP | -5761 |
| AXIN2 | -5745 |
| PSMA1 | -5730 |
| CSNK1D | -5722 |
| PCMT1 | -5697 |
| DDB1 | -5688 |
| MRPS6 | -5687 |
| EIF5A | -5678 |
| VCAN | -5649 |
| DDA1 | -5633 |
| DPH2 | -5629 |
| CCT8 | -5605 |
| PSMC1 | -5564 |
| NR5A2 | -5547 |
| PSMD3 | -5535 |
| SRP72 | -5526 |
| EDEM2 | -5520 |
| CDC34 | -5516 |
| TRIM25 | -5492 |
| FBXO31 | -5485 |
| PSME2 | -5481 |
| SEC24B | -5475 |
| SOCS6 | -5467 |
| RNF40 | -5459 |
| UBXN1 | -5450 |
| USP2 | -5430 |
| KIF5B | -5426 |
| B3GLCT | -5422 |
| DCAF10 | -5421 |
| PTRH2 | -5409 |
| RAB5A | -5408 |
| DPH1 | -5397 |
| PGM3 | -5395 |
| RAB2A | -5379 |
| MRPS15 | -5376 |
| PNPLA2 | -5366 |
| PSMD1 | -5351 |
| CPE | -5338 |
| TFG | -5336 |
| THSD1 | -5333 |
| GOLGA2 | -5310 |
| STX5 | -5300 |
| FBXO32 | -5299 |
| RHOA | -5294 |
| PUM2 | -5288 |
| RAB32 | -5287 |
| EIF3I | -5279 |
| PIGW | -5277 |
| NUP205 | -5275 |
| RAB35 | -5270 |
| USP22 | -5265 |
| RPL19 | -5254 |
| SMURF2 | -5253 |
| FSTL3 | -5252 |
| TPGS1 | -5251 |
| ASB6 | -5243 |
| PPP6C | -5241 |
| MRPL38 | -5234 |
| UCHL3 | -5231 |
| YY1 | -5214 |
| RABGGTB | -5199 |
| EIF2S1 | -5190 |
| PMM2 | -5187 |
| TADA2B | -5182 |
| SENP5 | -5170 |
| ACTR1A | -5162 |
| COPS2 | -5161 |
| MRPS2 | -5145 |
| RPS7 | -5138 |
| COPG1 | -5135 |
| FUT8 | -5134 |
| EIF3B | -5127 |
| EEF1D | -5115 |
| USP42 | -5109 |
| NUCB1 | -5103 |
| AURKAIP1 | -5100 |
| KDELR1 | -5094 |
| VAMP2 | -5088 |
| PTP4A2 | -5085 |
| MRPS12 | -5083 |
| DPH3 | -5074 |
| UBA52 | -5068 |
| ACTB | -5057 |
| LARGE1 | -5056 |
| EIF4H | -5055 |
| MRPL3 | -5054 |
| EEF2 | -5049 |
| VCPIP1 | -5042 |
| CSNK2A1 | -5040 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| PIAS4 | -5022 |
| RAB40C | -5019 |
| MGAT4A | -5018 |
| CD109 | -5016 |
| RPS15 | -5010 |
| RPA1 | -5008 |
| KIF13A | -4995 |
| NUP188 | -4991 |
| FAU | -4990 |
| DOLPP1 | -4988 |
| GBF1 | -4981 |
| RPL14 | -4978 |
| MRPL47 | -4976 |
| BPIFB2 | -4967 |
| ATXN7 | -4932 |
| EIF5A2 | -4929 |
| COMMD5 | -4916 |
| EPAS1 | -4915 |
| SPTBN1 | -4901 |
| YKT6 | -4899 |
| COPS8 | -4894 |
| PSMB6 | -4888 |
| WSB1 | -4879 |
| PSMC6 | -4878 |
| RAB31 | -4876 |
| KLHL42 | -4874 |
| MRPL14 | -4864 |
| SNX3 | -4858 |
| CAPZA1 | -4855 |
| B4GALT3 | -4852 |
| AREG | -4847 |
| NSF | -4839 |
| EIF2B5 | -4838 |
| EEF1B2 | -4836 |
| TRIM27 | -4835 |
| ST6GALNAC6 | -4820 |
| ARFGAP3 | -4817 |
| RNF181 | -4815 |
| EIF2B2 | -4811 |
| PSMC4 | -4808 |
| SRPRA | -4802 |
| MRPL23 | -4800 |
| KAT2B | -4792 |
| TNKS | -4790 |
| TGFBI | -4782 |
| GOLM1 | -4779 |
| RPS5 | -4778 |
| NUP88 | -4777 |
| CCDC59 | -4775 |
| FEM1C | -4764 |
| GALNT10 | -4763 |
| SPSB3 | -4739 |
| TCP1 | -4735 |
| NUP50 | -4733 |
| EIF3G | -4724 |
| PTEN | -4721 |
| EVA1A | -4709 |
| RPS11 | -4702 |
| FBXO44 | -4694 |
| CUL4B | -4685 |
| CDC73 | -4683 |
| RNF123 | -4681 |
| NR5A1 | -4679 |
| MMP2 | -4677 |
| RABGGTA | -4673 |
| NCOA1 | -4665 |
| RPS19 | -4661 |
| SP3 | -4660 |
| ANK1 | -4656 |
| HSPA8 | -4654 |
| RPS28 | -4652 |
| KDM1B | -4647 |
| PSMD9 | -4638 |
| TSPAN14 | -4626 |
| COPS3 | -4618 |
| MRPL34 | -4611 |
| DCUN1D2 | -4601 |
| MRPL41 | -4594 |
| TRAPPC2L | -4576 |
| MRPL35 | -4563 |
| GPLD1 | -4556 |
| DCAF5 | -4547 |
| CSNK2A2 | -4546 |
| EIF3J | -4539 |
| MRPL32 | -4532 |
| ARSD | -4527 |
| CALU | -4521 |
| ST3GAL2 | -4518 |
| GNB2 | -4514 |
| TGFA | -4511 |
| INHBE | -4510 |
| NSMCE2 | -4496 |
| MRPS18C | -4493 |
| SEH1L | -4472 |
| BCL10 | -4471 |
| MRPL51 | -4467 |
| EIF2S2 | -4458 |
| MRPL46 | -4455 |
| CTSC | -4446 |
| MBD1 | -4444 |
| USP34 | -4441 |
| TNIP1 | -4433 |
| STS | -4430 |
| NCOR2 | -4409 |
| RPLP1 | -4391 |
| PSMB7 | -4372 |
| CBX8 | -4370 |
| RPS12 | -4367 |
| EIF3M | -4358 |
| ALG1 | -4352 |
| USP15 | -4344 |
| UBE2M | -4337 |
| MRPS24 | -4327 |
| FOXK1 | -4324 |
| USP9X | -4318 |
| POLB | -4316 |
| B3GNT9 | -4301 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| PHC1 | -4280 |
| PIGA | -4278 |
| UBB | -4263 |
| DOHH | -4258 |
| COG2 | -4254 |
| TRIM4 | -4229 |
| AXIN1 | -4215 |
| PSMA4 | -4211 |
| HGS | -4210 |
| MRPL33 | -4189 |
| BMI1 | -4180 |
| ASB1 | -4171 |
| NUDT14 | -4170 |
| HIF1A | -4165 |
| P2RY2 | -4163 |
| RPL35A | -4159 |
| AFP | -4151 |
| EEF1A1 | -4138 |
| CUL1 | -4129 |
| COPB1 | -4098 |
| MRPL44 | -4094 |
| PSMC5 | -4091 |
| SMAD2 | -4087 |
| RPL30 | -4081 |
| RXRA | -4073 |
| MXRA8 | -4064 |
| CBX4 | -4063 |
| TMED3 | -4057 |
| SEC61G | -4052 |
| GALNT7 | -4049 |
| IDE | -4045 |
| TRAPPC3 | -4032 |
| RPS9 | -4028 |
| NFRKB | -4026 |
| GGCX | -4023 |
| EEF1E1 | -4013 |
| NR3C1 | -4005 |
| TULP4 | -4002 |
| UBE2D3 | -3997 |
| COG5 | -3964 |
| USP3 | -3962 |
| RPL18 | -3961 |
| COPA | -3958 |
| DCTN2 | -3957 |
| THRB | -3951 |
| FBXL20 | -3941 |
| CKAP4 | -3939 |
| WDR20 | -3937 |
| IGFBP1 | -3931 |
| TTR | -3924 |
| GADD45GIP1 | -3917 |
| POMT1 | -3914 |
| UBA2 | -3913 |
| MRPS22 | -3909 |
| EXOC3 | -3898 |
| DYNC1LI2 | -3897 |
| CTR9 | -3895 |
| ASB7 | -3889 |
| CREBBP | -3888 |
| RPL26L1 | -3873 |
| NAPG | -3872 |
| TRMT112 | -3869 |
| FBXO11 | -3853 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| ASB4 | -3822 |
| PSME3 | -3813 |
| FBXW11 | -3784 |
| SLC30A5 | -3771 |
| NUP98 | -3764 |
| EIF3D | -3740 |
| HERC2 | -3739 |
| SENP2 | -3731 |
| RBX1 | -3714 |
| TOP2B | -3712 |
| B4GAT1 | -3691 |
| TTLL7 | -3685 |
| APOE | -3670 |
| EIF2S3 | -3669 |
| RAB15 | -3665 |
| TGFBR2 | -3644 |
| GAN | -3641 |
| PEX14 | -3636 |
| DCTN5 | -3634 |
| PFDN2 | -3625 |
| DYNC1H1 | -3614 |
| EEF1G | -3612 |
| TXN | -3611 |
| ZNF131 | -3603 |
| SORL1 | -3586 |
| TRRAP | -3581 |
| RNF168 | -3576 |
| MAN1B1 | -3561 |
| ADRM1 | -3551 |
| KCTD7 | -3550 |
| RPL28 | -3546 |
| PABPC1 | -3543 |
| COMMD9 | -3531 |
| RPSA | -3520 |
| USO1 | -3509 |
| GPS1 | -3506 |
| MYO5A | -3500 |
| GOLGB1 | -3498 |
| USP12 | -3488 |
| RAB1B | -3479 |
| ADAMTSL2 | -3475 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| TUFM | -3458 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| LMAN1 | -3431 |
| LMAN2L | -3429 |
| XRN2 | -3427 |
| RPL37 | -3413 |
| INO80 | -3397 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| GMDS | -3350 |
| SIAH1 | -3347 |
| MRPS18B | -3346 |
| STAG1 | -3341 |
| APLP2 | -3330 |
| MGAT2 | -3327 |
| MDC1 | -3323 |
| DDX17 | -3321 |
| INO80D | -3312 |
| RAB1A | -3307 |
| TBCD | -3294 |
| MRPS36 | -3292 |
| VBP1 | -3287 |
| KLHL2 | -3269 |
| RPS14 | -3261 |
| ST3GAL6 | -3252 |
| ARRB2 | -3248 |
| CD59 | -3245 |
| GNB1 | -3237 |
| GALNT3 | -3227 |
| KTN1 | -3223 |
| TNKS2 | -3213 |
| ALG14 | -3206 |
| RPS27L | -3180 |
| PPARG | -3168 |
| ACTR8 | -3157 |
| RPS10 | -3155 |
| UBE2L3 | -3143 |
| SPHK1 | -3142 |
| SEM1 | -3130 |
| RAB5C | -3129 |
| FN1 | -3115 |
| MBD5 | -3114 |
| TDG | -3113 |
| TRIM28 | -3099 |
| LEO1 | -3088 |
| PSMA3 | -3078 |
| RNF139 | -3064 |
| COPS6 | -3063 |
| CUL3 | -3056 |
| SEC11A | -3046 |
| COPS5 | -3031 |
| RPS15A | -3019 |
| MRPL54 | -3013 |
| ELOB | -3004 |
| MRPL37 | -2997 |
| THRA | -2996 |
| ASGR2 | -2985 |
| RPL7 | -2984 |
| GPR119 | -2983 |
| RAB33B | -2981 |
| FARSA | -2976 |
| RPL34 | -2974 |
| SAR1B | -2973 |
| APOB | -2964 |
| MRPL36 | -2957 |
| C1GALT1C1 | -2939 |
| SATB2 | -2932 |
| PSMD8 | -2928 |
| RPS21 | -2927 |
| CCT3 | -2912 |
| NGLY1 | -2909 |
| BECN1 | -2900 |
| RPS16 | -2898 |
| RIPK1 | -2886 |
| RPS3 | -2880 |
| TPST2 | -2873 |
| RPL13A | -2872 |
| VDAC2 | -2869 |
| RPLP2 | -2863 |
| LARGE2 | -2856 |
| RPL35 | -2849 |
| USP5 | -2837 |
| GFM1 | -2827 |
| USP8 | -2820 |
| HNRNPK | -2808 |
| TOMM70 | -2797 |
| USP24 | -2786 |
| IGFBP6 | -2783 |
| PFDN5 | -2781 |
| DYNC1I2 | -2780 |
| RPS27A | -2773 |
| BAP1 | -2760 |
| TOPORS | -2753 |
| UHRF2 | -2752 |
| MRRF | -2721 |
| SEC23A | -2717 |
| MRPL57 | -2716 |
| PSMA5 | -2715 |
| MRPS34 | -2704 |
| AMFR | -2698 |
| EID3 | -2695 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| HDAC1 | -2676 |
| ADAM10 | -2671 |
| MRPS23 | -2664 |
| PMM1 | -2658 |
| UBE2E3 | -2654 |
| RPS18 | -2648 |
| TTL | -2640 |
| RPL41 | -2635 |
| RELA | -2632 |
| TGFBR1 | -2620 |
| STAG2 | -2617 |
| FBXL14 | -2614 |
| MRPL48 | -2613 |
| HIC1 | -2592 |
| UBE2B | -2586 |
| CYR61 | -2582 |
| RPS13 | -2581 |
| PSMD13 | -2577 |
| GFM2 | -2567 |
| FBXW7 | -2564 |
| RPL4 | -2563 |
| MDM4 | -2561 |
| FBXW10 | -2540 |
| B2M | -2523 |
| DYNC1LI1 | -2519 |
| PARK7 | -2508 |
| OTULIN | -2499 |
| B4GALT2 | -2487 |
| MRPS28 | -2470 |
| DCAF6 | -2469 |
| RPS23 | -2467 |
| SP100 | -2455 |
| RPL37A | -2451 |
| ADAMTS17 | -2445 |
| ARF3 | -2430 |
| B3GALNT2 | -2427 |
| USP19 | -2419 |
| MRPL39 | -2415 |
| ERCC8 | -2409 |
| EIF3L | -2407 |
| GPAA1 | -2406 |
| PSMC2 | -2389 |
| STX1A | -2377 |
| B3GNT2 | -2359 |
| PSME1 | -2348 |
| OTUD3 | -2342 |
| CDH2 | -2339 |
| MAN2A2 | -2336 |
| PSENEN | -2327 |
| INHBB | -2320 |
| DPH7 | -2301 |
| PRKDC | -2300 |
| SUDS3 | -2287 |
| MOGS | -2275 |
| MRPS11 | -2271 |
| RPL39 | -2270 |
| UBA6 | -2266 |
| CUL4A | -2265 |
| RAB8A | -2247 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| EIF3K | -2206 |
| DAG1 | -2174 |
| TSPAN5 | -2154 |
| RAB4A | -2148 |
| TPST1 | -2126 |
| RPS4Y1 | -2120 |
| DPM2 | -2111 |
| FBXL19 | -2110 |
| TGOLN2 | -2105 |
| SMC5 | -2095 |
| FOXO4 | -2077 |
| RPL27 | -2070 |
| NPM1 | -2033 |
| FBXL3 | -2027 |
| MRPL22 | -2025 |
| CCNE2 | -2024 |
| RFWD2 | -2022 |
| TP53 | -2020 |
| UBE2W | -1973 |
| SRP54 | -1969 |
| CNIH3 | -1958 |
| DCTN4 | -1937 |
| NUP214 | -1926 |
| MRPL4 | -1923 |
| SVBP | -1922 |
| PSMB3 | -1915 |
| RPL23 | -1913 |
| OTUD7B | -1911 |
| ASXL1 | -1908 |
| LTBP1 | -1904 |
| EDEM3 | -1903 |
| DCUN1D5 | -1895 |
| ASGR1 | -1889 |
| PIGH | -1877 |
| UBE2S | -1872 |
| USP47 | -1849 |
| FBXO9 | -1843 |
| B3GNT4 | -1829 |
| ST6GAL1 | -1828 |
| VARS2 | -1827 |
| ZDHHC2 | -1819 |
| APC | -1818 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RAB39B | -1774 |
| IARS2 | -1767 |
| ST8SIA5 | -1758 |
| RPS20 | -1754 |
| RTF1 | -1751 |
| RPL26 | -1747 |
| EEF1A1P5 | -1745 |
| RAB3B | -1738 |
| MSRA | -1733 |
| CCDC22 | -1703 |
| SEC22C | -1684 |
| USP28 | -1668 |
| CAND1 | -1658 |
| MRPS30 | -1657 |
| DCTN1 | -1635 |
| ARFGAP1 | -1587 |
| FEM1A | -1576 |
| PPA1 | -1553 |
| CAPZA2 | -1549 |
| MUC13 | -1524 |
| PSMC3 | -1509 |
| FBXL18 | -1507 |
| NDC1 | -1490 |
| HDAC4 | -1478 |
| MCRS1 | -1472 |
| CCT7 | -1465 |
| NSMCE4A | -1462 |
| MRPS35 | -1461 |
| CCT4 | -1418 |
| SEC61A2 | -1397 |
| MRPL53 | -1391 |
| RAB2B | -1387 |
| PIAS3 | -1381 |
| ACTL6A | -1378 |
| RNF128 | -1375 |
| SOCS2 | -1346 |
| MYRIP | -1341 |
| PIGN | -1322 |
| CHD3 | -1321 |
| UBE2I | -1318 |
| TNIP2 | -1314 |
| RPL15 | -1313 |
| NFKB2 | -1311 |
| SPSB2 | -1306 |
| WDTC1 | -1303 |
| LAMC1 | -1300 |
| TUBA8 | -1280 |
| UBA3 | -1275 |
| ARSK | -1251 |
| QSOX1 | -1250 |
| LMO7 | -1246 |
| ATP6AP2 | -1245 |
| DPM1 | -1233 |
| CUL5 | -1229 |
| KLHL11 | -1223 |
| TUSC3 | -1219 |
| TADA3 | -1216 |
| CAPZB | -1169 |
| RPL3 | -1165 |
| PIGT | -1154 |
| ACHE | -1152 |
| NOP56 | -1145 |
| PSMB4 | -1144 |
| FBXL12 | -1137 |
| RCE1 | -1124 |
| RPL17 | -1119 |
| TUBB6 | -1115 |
| ASB8 | -1103 |
| TSFM | -1098 |
| ADAMTSL5 | -1090 |
| RPS8 | -1071 |
| MAN2A1 | -1040 |
| VDAC1 | -1027 |
| TTLL9 | -1023 |
| MAN1A1 | -1021 |
| MUC20 | -1019 |
| GNB3 | -1008 |
| MRPS9 | -1007 |
| PDCL | -1005 |
| KLHL5 | -991 |
| RPL12 | -983 |
| UBE2Z | -964 |
| MDM2 | -956 |
| RPS25 | -937 |
| DDX58 | -927 |
| UBE2D2 | -913 |
| UAP1 | -898 |
| EIF3F | -893 |
| PSMA7 | -892 |
| SENP1 | -886 |
| MRPL18 | -882 |
| RAB11B | -876 |
| FBXL13 | -870 |
| COPS7B | -839 |
| GALNT1 | -816 |
| GALNT13 | -810 |
| IKBKE | -787 |
| EXOC2 | -747 |
| PSMB5 | -742 |
| MRPL9 | -726 |
| PEX13 | -721 |
| SFTPB | -720 |
| UBE2G2 | -718 |
| TTLL5 | -713 |
| ING2 | -711 |
| RPL13 | -706 |
| CALM1 | -655 |
| YARS2 | -645 |
| LRRC49 | -625 |
| PPP6R3 | -623 |
| MSRB3 | -621 |
| RNF7 | -611 |
| PIGS | -609 |
| ASB18 | -601 |
| TRAF2 | -577 |
| TTLL12 | -556 |
| NCSTN | -554 |
| SKP1 | -544 |
| MRPS18A | -532 |
| SARS2 | -521 |
| INHA | -500 |
| BIRC2 | -499 |
| RPL5 | -495 |
| LRR1 | -494 |
| PAX6 | -478 |
| MRPS10 | -474 |
| MRPL40 | -473 |
| PSMD11 | -432 |
| ALG9 | -426 |
| NAPB | -419 |
| MRPL50 | -402 |
| DCUN1D4 | -400 |
| UBE2R2 | -386 |
| EIF3C | -374 |
| RAB18 | -372 |
| TRAF3 | -356 |
| PEX5 | -346 |
| HDAC2 | -338 |
| NUP160 | -329 |
| USP25 | -325 |
| DCTN6 | -318 |
| NUP62 | -299 |
| LYPD3 | -297 |
| FBXW2 | -294 |
| OTUB1 | -293 |
| EIF1AX | -274 |
| VDAC3 | -273 |
| PIAS1 | -272 |
| POFUT2 | -264 |
| B4GALT1 | -262 |
| KLHL25 | -215 |
| RPL22L1 | -214 |
| ERO1A | -198 |
| INO80C | -185 |
| RPS3A | -179 |
| KCTD6 | -178 |
| MTIF3 | -173 |
| ANO8 | -168 |
| RPS27 | -152 |
| EIF2B1 | -143 |
| PSMA6 | -126 |
| FEM1B | -103 |
| RBBP5 | -101 |
| EXOC8 | -92 |
| FBXO2 | -78 |
| CTBP1 | -41 |
| COPS4 | -28 |
| RANBP2 | -4 |
| COMMD4 | -2 |
| FBXO10 | 18 |
| AHSG | 25 |
| BTBD1 | 37 |
| HDAC3 | 38 |
| CSF2RA | 43 |
| PIGX | 63 |
| OTOA | 87 |
| MRPL19 | 96 |
| DOLK | 108 |
| COMMD10 | 117 |
| RNF135 | 126 |
| HDAC7 | 130 |
| USP7 | 134 |
| FBXO30 | 137 |
| SDC2 | 147 |
| NR1H2 | 193 |
| CNIH1 | 212 |
| APOA4 | 226 |
| TRAPPC5 | 239 |
| BGLAP | 241 |
| RPL9 | 261 |
| MITF | 267 |
| RAB30 | 288 |
| ANK3 | 303 |
| RPL31 | 330 |
| EXOC5 | 337 |
| SUZ12 | 346 |
| CUL2 | 359 |
| UBE2K | 383 |
| PIAS2 | 388 |
| SEC23IP | 390 |
| COMMD2 | 395 |
| RPS26 | 419 |
| PSMB10 | 423 |
| TUBB3 | 436 |
| EIF2B4 | 437 |
| UCHL5 | 443 |
| WDR61 | 452 |
| BET1 | 457 |
| MRPL13 | 482 |
| NANP | 483 |
| SCFD1 | 485 |
| LAMB2 | 495 |
| UBA1 | 516 |
| NR2C1 | 535 |
| WDR48 | 543 |
| EEF1A2 | 553 |
| CCT6B | 563 |
| TPR | 565 |
| NRIP1 | 570 |
| NEDD8 | 580 |
| OTUD7A | 589 |
| RAD21 | 601 |
| FBXL15 | 612 |
| APH1A | 619 |
| GOSR1 | 621 |
| TAF10 | 626 |
| F2 | 635 |
| ELOC | 645 |
| PRSS23 | 655 |
| MTIF2 | 664 |
| TOMM20 | 676 |
| GCNT1 | 679 |
| TUBA4A | 682 |
| GNB5 | 700 |
| COMMD8 | 710 |
| BST1 | 713 |
| F8 | 735 |
| C1GALT1 | 742 |
| MRPL20 | 773 |
| UBC | 779 |
| COPZ1 | 782 |
| SMC1A | 784 |
| MRPS14 | 785 |
| MRPS5 | 787 |
| L3MBTL2 | 789 |
| GNAQ | 803 |
| GP2 | 806 |
| RNF146 | 825 |
| F5 | 831 |
| PHC3 | 843 |
| SEC22B | 859 |
| EEF2KMT | 867 |
| LMCD1 | 888 |
| FBXW9 | 890 |
| MRPS17 | 895 |
| EIF3H | 899 |
| TBCE | 923 |
| FBXO7 | 947 |
| PIGY | 948 |
| RAB12 | 950 |
| TCF7L2 | 959 |
| CAMKMT | 962 |
| DAP3 | 972 |
| KDELR3 | 976 |
| CEACAM5 | 1008 |
| USP10 | 1016 |
| ARFGEF2 | 1022 |
| MRPL28 | 1039 |
| PML | 1051 |
| EXOC4 | 1053 |
| PSMB1 | 1054 |
| CHCHD1 | 1058 |
| MYSM1 | 1066 |
| AIMP2 | 1067 |
| PIGU | 1074 |
| SPSB1 | 1077 |
| NSMCE3 | 1095 |
| SUMF2 | 1101 |
| ALG8 | 1117 |
| UBXN7 | 1120 |
| CPM | 1144 |
| TFPT | 1213 |
| AURKA | 1224 |
| GOSR2 | 1238 |
| ADAMTS4 | 1241 |
| USP20 | 1248 |
| EARS2 | 1253 |
| ARFGAP2 | 1283 |
| TUBB2A | 1290 |
| CCNF | 1291 |
| RAB6A | 1296 |
| MEN1 | 1298 |
| FN3K | 1324 |
| FARS2 | 1328 |
| MRPL58 | 1346 |
| ALG13 | 1348 |
| NUP133 | 1362 |
| MBOAT4 | 1368 |
| RPL21 | 1385 |
| BTRC | 1386 |
| B4GALNT2 | 1387 |
| B3GNTL1 | 1392 |
| RAB6B | 1396 |
| USP49 | 1405 |
| MRPL15 | 1406 |
| UGGT2 | 1425 |
| DCUN1D1 | 1428 |
| PAPPA | 1432 |
| PREB | 1446 |
| USP4 | 1449 |
| DCTN3 | 1457 |
| CALB1 | 1461 |
| GSN | 1496 |
| PTCD3 | 1514 |
| NR3C2 | 1520 |
| GLB1 | 1557 |
| SUMO2 | 1568 |
| B3GNT7 | 1584 |
| SPP2 | 1592 |
| TRAF6 | 1597 |
| RAB3D | 1600 |
| RAB10 | 1625 |
| RAB29 | 1630 |
| MRPL52 | 1657 |
| MAVS | 1695 |
| MAT2B | 1703 |
| MGAT4C | 1714 |
| ITIH2 | 1740 |
| CHML | 1746 |
| MRPS7 | 1777 |
| TRAPPC4 | 1781 |
| AIMP1 | 1790 |
| SAE1 | 1799 |
| TBCB | 1809 |
| MTA1 | 1810 |
| HNRNPC | 1814 |
| PAF1 | 1828 |
| UBE2N | 1836 |
| MSRB1 | 1864 |
| AGBL3 | 1865 |
| NEGR1 | 1869 |
| PSMB2 | 1876 |
| TRIM13 | 1883 |
| MYC | 1892 |
| GORASP1 | 1903 |
| USP33 | 1924 |
| GNB4 | 1936 |
| NAT8 | 1943 |
| MARS2 | 1957 |
| COG4 | 1972 |
| LRRC41 | 1992 |
| TTLL4 | 2011 |
| ETFB | 2051 |
| CARS2 | 2078 |
| FGF23 | 2097 |
| NARS2 | 2113 |
| PIGC | 2130 |
| DNMT1 | 2134 |
| RPL22 | 2142 |
| SMC6 | 2150 |
| WRAP53 | 2169 |
| ZNF350 | 2186 |
| STAMBPL1 | 2213 |
| CHGB | 2226 |
| INHBC | 2246 |
| KIF5C | 2266 |
| ST8SIA1 | 2289 |
| PIGO | 2315 |
| METTL22 | 2346 |
| ERAL1 | 2351 |
| BRCC3 | 2358 |
| NEURL2 | 2359 |
| OXA1L | 2372 |
| TMEM132A | 2376 |
| NUP58 | 2380 |
| MRPS27 | 2381 |
| SPTAN1 | 2385 |
| OBSL1 | 2391 |
| GNPNAT1 | 2394 |
| DHDDS | 2399 |
| TECTA | 2402 |
| PPA2 | 2403 |
| USP48 | 2408 |
| SPCS1 | 2416 |
| GALNT4 | 2438 |
| RNF2 | 2454 |
| VASH1 | 2462 |
| DARS2 | 2466 |
| CCDC8 | 2470 |
| EIF4E | 2473 |
| POMK | 2475 |
| GATA6 | 2495 |
| EXOC6 | 2506 |
| DYNLL1 | 2509 |
| THBS2 | 2512 |
| MRPL21 | 2518 |
| GGA1 | 2520 |
| SMC3 | 2546 |
| WDR5 | 2561 |
| FUOM | 2573 |
| DNAJC24 | 2574 |
| TARS2 | 2575 |
| TRAPPC6B | 2584 |
| STX17 | 2586 |
| B4GALT4 | 2602 |
| AGBL5 | 2606 |
| RRAGA | 2609 |
| UBE2Q2 | 2642 |
| ALG10 | 2654 |
| PEX10 | 2668 |
| ANKRD9 | 2692 |
| RAB21 | 2694 |
| FUCA1 | 2696 |
| GAS6 | 2708 |
| NUP153 | 2712 |
| TUBB1 | 2717 |
| RAB26 | 2740 |
| SMAD4 | 2742 |
| MRPL27 | 2747 |
| CCNE1 | 2754 |
| ACE2 | 2757 |
| USP11 | 2763 |
| HLA-B | 2764 |
| TBCC | 2785 |
| GALNT16 | 2794 |
| USP21 | 2804 |
| NUP43 | 2808 |
| CTSD | 2812 |
| GANAB | 2813 |
| INO80B | 2818 |
| VWA1 | 2832 |
| RGS9 | 2861 |
| RPL36A | 2875 |
| ARSA | 2878 |
| ADAMTS7 | 2880 |
| B4GALT6 | 2881 |
| RAB5B | 2913 |
| FBXL8 | 2924 |
| KBTBD8 | 2943 |
| ADAMTSL3 | 2956 |
| PFDN4 | 2960 |
| AAAS | 2965 |
| PARP1 | 2974 |
| BABAM1 | 2979 |
| ICMT | 2988 |
| RAB27A | 3011 |
| ASB3 | 3026 |
| WRN | 3032 |
| ABCA3 | 3033 |
| MAN1C1 | 3072 |
| STAM2 | 3080 |
| TRAPPC1 | 3089 |
| ALB | 3096 |
| FBXL22 | 3108 |
| SMAD7 | 3117 |
| RAD23B | 3141 |
| MTFMT | 3156 |
| RAB4B | 3174 |
| POMGNT1 | 3215 |
| DPM3 | 3217 |
| EIF3E | 3244 |
| MRPS26 | 3245 |
| COG6 | 3264 |
| FARSB | 3269 |
| CTNNB1 | 3272 |
| SUMO1 | 3308 |
| NUP54 | 3310 |
| SEC22A | 3312 |
| EIF5B | 3318 |
| KLHL20 | 3344 |
| DNMT3A | 3360 |
| UBE2V2 | 3369 |
| XRCC4 | 3376 |
| PIGP | 3397 |
| RCN1 | 3434 |
| ZBED1 | 3448 |
| RANGAP1 | 3458 |
| UBD | 3463 |
| DHPS | 3475 |
| BIRC3 | 3477 |
| BET1L | 3487 |
| UBE2D1 | 3523 |
| EXOC7 | 3531 |
| TRAPPC2 | 3547 |
| FBXO15 | 3559 |
| B3GNT8 | 3574 |
| KIN | 3578 |
| FBXO27 | 3623 |
| DAXX | 3635 |
| RAB14 | 3647 |
| GCNT4 | 3690 |
| CDKN2A | 3704 |
| KLHL9 | 3712 |
| PHC2 | 3713 |
| ATXN3 | 3714 |
| FBXW8 | 3716 |
| MPDU1 | 3718 |
| RAB13 | 3724 |
| ITM2B | 3727 |
| MRPL10 | 3731 |
| CST3 | 3732 |
| UBE2E1 | 3733 |
| UBE2A | 3752 |
| MAP3K7 | 3767 |
| ADAMTS1 | 3770 |
| LAMB1 | 3783 |
| USP37 | 3800 |
| LYZ | 3804 |
| ETFBKMT | 3805 |
| JOSD2 | 3811 |
| AP3M1 | 3816 |
| DCAF17 | 3819 |
| SPTBN2 | 3883 |
| NUB1 | 3894 |
| SLC35A1 | 3906 |
| INO80E | 3921 |
| FBXO6 | 3932 |
| TBCA | 3995 |
| SERPINA1 | 4014 |
| RAB24 | 4024 |
| TUBB8 | 4034 |
| MRPL49 | 4062 |
| RING1 | 4067 |
| MRPL11 | 4075 |
| WARS2 | 4080 |
| NRN1L | 4081 |
| RHOT1 | 4106 |
| APOA5 | 4116 |
| GNG5 | 4123 |
| ANKRD28 | 4146 |
| ACTR5 | 4150 |
| NUP85 | 4178 |
| FBXO4 | 4180 |
| TUBB2B | 4184 |
| GPC3 | 4191 |
| GGA3 | 4199 |
| PIGV | 4200 |
| MANEA | 4202 |
| SERPINA10 | 4206 |
| TSPAN33 | 4207 |
| TSPAN15 | 4238 |
| SLC30A6 | 4251 |
| STAT3 | 4253 |
| MRPL12 | 4261 |
| IGFBP7 | 4272 |
| KLHL13 | 4291 |
| PIGB | 4297 |
| PSMD12 | 4303 |
| COMMD1 | 4304 |
| RAB3A | 4309 |
| VCPKMT | 4329 |
| CPB2 | 4337 |
| TNFAIP3 | 4359 |
| CUL7 | 4377 |
| RAE1 | 4394 |
| CSNK2B | 4415 |
| GNG7 | 4426 |
| RAB42 | 4442 |
| HIF3A | 4444 |
| LY6E | 4473 |
| PLAUR | 4485 |
| POMGNT2 | 4488 |
| RNF144A | 4501 |
| NAGK | 4508 |
| RAB11A | 4527 |
| PIGQ | 4551 |
| MSLN | 4555 |
| PSMD4 | 4567 |
| PEX2 | 4569 |
| DTL | 4577 |
| COG1 | 4586 |
| SKIV2L | 4599 |
| PFDN1 | 4605 |
| B3GNT3 | 4629 |
| DCAF8 | 4645 |
| DCAF13 | 4652 |
| RAB40B | 4658 |
| RAB8B | 4676 |
| NR1H3 | 4678 |
| ANPEP | 4690 |
| APEH | 4698 |
| MRPS33 | 4704 |
| TUBA1A | 4706 |
| RAB23 | 4722 |
| PEX12 | 4742 |
| ARF5 | 4743 |
| SRD5A3 | 4758 |
| FBXO22 | 4762 |
| NCOA2 | 4780 |
| TP53BP1 | 4788 |
| MRPL43 | 4791 |
| COG7 | 4792 |
| NUP155 | 4796 |
| FBXL4 | 4801 |
| PIGF | 4815 |
| MUC15 | 4828 |
| NICN1 | 4839 |
| SHISA5 | 4853 |
| EIF4EBP1 | 4858 |
| MRPS21 | 4888 |
| APOL1 | 4896 |
| SUMO3 | 4906 |
| TMEM129 | 4918 |
| PSMD10 | 4933 |
| GALNT6 | 4939 |
| PSMD7 | 4942 |
| ALG6 | 4943 |
| FAM20C | 4945 |
| RAB36 | 4950 |
| SMAD1 | 4977 |
| FBXO21 | 4978 |
| COMMD3 | 4983 |
| RTN4RL2 | 5004 |
| TRAPPC9 | 5033 |
| ADAMTS13 | 5043 |
| IGFBP4 | 5060 |
| MPI | 5076 |
| KAT2A | 5077 |
| RFT1 | 5083 |
| KLHL22 | 5084 |
| RARS2 | 5085 |
| ST3GAL5 | 5090 |
| BRCA1 | 5107 |
| STAM | 5109 |
| PSMD5 | 5116 |
| PFDN6 | 5123 |
| ADORA2B | 5127 |
| RBBP7 | 5134 |
| ASB9 | 5150 |
| TTF1 | 5165 |
| BIRC5 | 5174 |
| COMMD7 | 5185 |
| AGBL2 | 5191 |
| EIF2B3 | 5203 |
| USP14 | 5232 |
| METTL21A | 5233 |
| PIGM | 5248 |
| CASP8AP2 | 5260 |
| INCENP | 5290 |
| RUVBL1 | 5317 |
| ADORA2A | 5330 |
| MRPL42 | 5341 |
| DCAF16 | 5344 |
| XPC | 5353 |
| H2AFX | 5356 |
| COL7A1 | 5362 |
| UBE2H | 5369 |
| AMDHD2 | 5414 |
| DCAF4 | 5420 |
| CHM | 5425 |
| NOD1 | 5449 |
| PSMB9 | 5491 |
| DPH6 | 5513 |
| PIGZ | 5536 |
| VNN1 | 5548 |
| MFGE8 | 5552 |
| DCAF7 | 5557 |
| ACTR10 | 5570 |
| EIF4A2 | 5593 |
| SRP9 | 5604 |
| NOP58 | 5612 |
| TPGS2 | 5616 |
| FPGT | 5627 |
| CDC20 | 5650 |
| COPS7A | 5653 |
| CTSH | 5655 |
| NR1I2 | 5656 |
| COMMD6 | 5668 |
| FBXL5 | 5669 |
| HARS2 | 5687 |
| PRMT3 | 5707 |
| UBE2T | 5710 |
| ARL2 | 5716 |
| CMAS | 5724 |
| F10 | 5732 |
| NAE1 | 5740 |
| AARS2 | 5743 |
| HLA-A | 5777 |
| UCN | 5800 |
| CETN2 | 5801 |
| AGTPBP1 | 5818 |
| MRPL55 | 5826 |
| NUP93 | 5831 |
| RNF20 | 5837 |
| PIGL | 5841 |
| TF | 5850 |
| IGFALS | 5854 |
| MSRB2 | 5860 |
| MRPL1 | 5865 |
| STAMBP | 5873 |
| USP18 | 5875 |
| MRPL16 | 5878 |
| MRPS16 | 5883 |
| ALG10B | 5899 |
| OTUB2 | 5916 |
| ST3GAL3 | 5918 |
| MRPL17 | 5943 |
| VASH2 | 5945 |
| SKP2 | 5946 |
| PGAP1 | 5952 |
| CDC25A | 5954 |
| HRC | 5955 |
| MRPL30 | 5960 |
| PSMD14 | 5974 |
| NUP35 | 5982 |
| FBXO17 | 5986 |
| THBS1 | 5988 |
| BLM | 5994 |
| CISH | 6003 |
| FBXW4 | 6039 |
| XPNPEP2 | 6043 |
| DYNLL2 | 6044 |
| RAD18 | 6045 |
| GNE | 6051 |
| PROS1 | 6053 |
| USP13 | 6054 |
| IGFBP3 | 6060 |
| NUP107 | 6076 |
| BACE1 | 6090 |
| TAF9B | 6106 |
| ARSI | 6118 |
| MRPL2 | 6122 |
| LARS2 | 6133 |
| SENP8 | 6135 |
| FBXO41 | 6136 |
| BARD1 | 6138 |
| COPG2 | 6142 |
| SHPRH | 6150 |
| GNG4 | 6164 |
| APH1B | 6168 |
| SUMF1 | 6175 |
| RAD52 | 6185 |
| MRPS31 | 6190 |
| CCP110 | 6203 |
| PROZ | 6212 |
| PIGK | 6215 |
| FKBP8 | 6242 |
| HIPK2 | 6284 |
| EXOC1 | 6302 |
| F7 | 6332 |
| VNN3 | 6337 |
| USP30 | 6349 |
| IGFBP2 | 6370 |
| ASB13 | 6386 |
| ADAMTS9 | 6402 |
| FN3KRP | 6434 |
| OGT | 6452 |
| ENGASE | 6457 |
| ADAMTS6 | 6501 |
| PCNA | 6523 |
| GALNT2 | 6578 |
| CCNA2 | 6594 |
| RWDD3 | 6644 |
| IFIH1 | 6646 |
| CDCA8 | 6649 |
| SCMH1 | 6656 |
| NSMCE1 | 6680 |
| ART4 | 6681 |
| TAB1 | 6687 |
| SERPIND1 | 6689 |
| FGG | 6697 |
| PROC | 6720 |
| TTLL1 | 6723 |
| DPH5 | 6731 |
| SEC16B | 6744 |
| COG8 | 6745 |
| DDB2 | 6754 |
| TUBB4B | 6758 |
| TUBA1C | 6761 |
| HLTF | 6769 |
| KBTBD7 | 6772 |
| CUL9 | 6773 |
| GNG10 | 6779 |
| NOTUM | 6788 |
| KBTBD6 | 6796 |
| NUP210 | 6802 |
| B4GALT5 | 6846 |
| TOP2A | 6875 |
| AURKB | 6883 |
| CHST10 | 6919 |
| ADAMTS2 | 6939 |
| NEU4 | 6950 |
| DNMT3B | 6957 |
| CBX2 | 6958 |
| ADAMTS10 | 6971 |
| MRPL24 | 6982 |
| RAB37 | 6989 |
| APOA1 | 6993 |
| CLSPN | 7014 |
| CES1 | 7025 |
| ADAMTSL4 | 7040 |
| NEU3 | 7085 |
| MRPS25 | 7089 |
| AGT | 7091 |
| TUBA1B | 7094 |
| NUP37 | 7100 |
| TTLL3 | 7102 |
| FKBP9 | 7108 |
| PARS2 | 7123 |
| GALNT11 | 7125 |
| RECK | 7128 |
| UBE2C | 7137 |
| RAD23A | 7141 |
| N6AMT1 | 7144 |
| FBN1 | 7148 |
| HSPG2 | 7157 |
| CBX5 | 7222 |
| CDK1 | 7230 |
| TRAPPC6A | 7244 |
| FBXL16 | 7269 |
| UBE2L6 | 7272 |
| MELTF | 7295 |
| MATN3 | 7298 |
| MVD | 7302 |
| ODAM | 7310 |
| CP | 7325 |
| FAM20A | 7332 |
| FGA | 7336 |
| ARSG | 7341 |
| C4A | 7346 |
| C3 | 7357 |
| SOCS3 | 7374 |
| IGF2 | 7375 |
| MUC5B | 7378 |
| PLG | 7380 |
| PCSK9 | 7381 |
| KNG1 | 7382 |
Nervous system development
| 708 | |
|---|---|
| set | Nervous system development |
| setSize | 444 |
| pANOVA | 6.25e-14 |
| s.dist | -0.209 |
| p.adjustANOVA | 9.56e-12 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| VASP | -7075 |
| ABLIM1 | -7055 |
| RPL36AL | -6981 |
| ETF1 | -6952 |
| RNPS1 | -6938 |
| ARHGEF28 | -6925 |
| SHC1 | -6910 |
| MET | -6878 |
| RANBP9 | -6871 |
| EPHA2 | -6857 |
| ACTG1 | -6841 |
| GSPT1 | -6825 |
| ANK2 | -6778 |
| SEMA6A | -6761 |
| RHOC | -6747 |
| SCN2A | -6712 |
| SIAH2 | -6666 |
| PSMF1 | -6663 |
| MYL12B | -6653 |
| WASL | -6543 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| VASP | -7075 |
| ABLIM1 | -7055 |
| RPL36AL | -6981 |
| ETF1 | -6952 |
| RNPS1 | -6938 |
| ARHGEF28 | -6925 |
| SHC1 | -6910 |
| MET | -6878 |
| RANBP9 | -6871 |
| EPHA2 | -6857 |
| ACTG1 | -6841 |
| GSPT1 | -6825 |
| ANK2 | -6778 |
| SEMA6A | -6761 |
| RHOC | -6747 |
| SCN2A | -6712 |
| SIAH2 | -6666 |
| PSMF1 | -6663 |
| MYL12B | -6653 |
| WASL | -6543 |
| DNM2 | -6535 |
| DPYSL2 | -6519 |
| ITGA10 | -6466 |
| PSME4 | -6450 |
| ARHGAP35 | -6446 |
| CLTA | -6439 |
| PSMD2 | -6435 |
| MYL6 | -6380 |
| NAB2 | -6372 |
| PLXNA3 | -6318 |
| ARHGAP39 | -6303 |
| PFN1 | -6285 |
| UNC5B | -6252 |
| CLTC | -6220 |
| ITGA2 | -6205 |
| FGFR1 | -6191 |
| UPF3A | -6189 |
| TLN1 | -6146 |
| PRNP | -6115 |
| ARPC4 | -6094 |
| MAP2K2 | -6087 |
| CLTB | -6064 |
| CASC3 | -5986 |
| PSMD6 | -5951 |
| MYO9B | -5920 |
| EIF4G1 | -5901 |
| EFNA1 | -5830 |
| PSMA2 | -5801 |
| CFL1 | -5737 |
| PSMA1 | -5730 |
| PLXND1 | -5686 |
| CACNA1D | -5676 |
| PITPNA | -5591 |
| GIT1 | -5582 |
| ROBO1 | -5577 |
| PSMC1 | -5564 |
| HRAS | -5543 |
| MAPK12 | -5538 |
| PSMD3 | -5535 |
| GRB10 | -5504 |
| PSME2 | -5481 |
| IRS2 | -5461 |
| SOS2 | -5417 |
| EGFR | -5383 |
| PAK4 | -5359 |
| PSMD1 | -5351 |
| TRIO | -5341 |
| NRP2 | -5313 |
| ACTR3 | -5296 |
| RHOA | -5294 |
| MYO10 | -5290 |
| ZSWIM8 | -5267 |
| ARHGEF11 | -5260 |
| RPL19 | -5254 |
| NUMB | -5224 |
| PSPN | -5177 |
| EPHB1 | -5141 |
| RPS7 | -5138 |
| GSK3B | -5101 |
| UBA52 | -5068 |
| MAPK1 | -5066 |
| ACTB | -5057 |
| CSNK2A1 | -5040 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| RAP1GAP | -4998 |
| FAU | -4990 |
| RPL14 | -4978 |
| PAK2 | -4957 |
| PSEN1 | -4938 |
| SPTBN1 | -4901 |
| PSMB6 | -4888 |
| PSMC6 | -4878 |
| PSMC4 | -4808 |
| RPS5 | -4778 |
| PIK3CD | -4759 |
| MYH9 | -4726 |
| RPS11 | -4702 |
| MMP2 | -4677 |
| RPS19 | -4661 |
| ANK1 | -4656 |
| HSPA8 | -4654 |
| RPS28 | -4652 |
| VAV3 | -4642 |
| PSMD9 | -4638 |
| AP2M1 | -4603 |
| CSNK2A2 | -4546 |
| EZR | -4464 |
| ARPC1B | -4429 |
| HSP90AB1 | -4426 |
| RPLP1 | -4391 |
| MAPK7 | -4382 |
| EPHB4 | -4379 |
| PIK3R1 | -4376 |
| PSMB7 | -4372 |
| RPS12 | -4367 |
| PTK2 | -4346 |
| ITGAV | -4312 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| UBB | -4263 |
| CLASP2 | -4246 |
| PSMA4 | -4211 |
| RPL35A | -4159 |
| ITGB1 | -4145 |
| GAB2 | -4127 |
| MAP2K1 | -4120 |
| UTRN | -4105 |
| LYPLA2 | -4095 |
| PSMC5 | -4091 |
| CAP1 | -4085 |
| RPL30 | -4081 |
| PPP3CB | -4060 |
| RPS9 | -4028 |
| GRB7 | -4006 |
| GDNF | -3969 |
| RPL18 | -3961 |
| NCK2 | -3916 |
| CACNA1H | -3915 |
| RPL26L1 | -3873 |
| DLG1 | -3865 |
| RPS6KA1 | -3857 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| UPF2 | -3830 |
| NRCAM | -3815 |
| PLXNA2 | -3814 |
| PSME3 | -3813 |
| FRS2 | -3790 |
| SHC3 | -3782 |
| PLXNB3 | -3778 |
| RBX1 | -3714 |
| ROCK1 | -3594 |
| RPL28 | -3546 |
| PABPC1 | -3543 |
| RPSA | -3520 |
| AP2A2 | -3499 |
| EFNB2 | -3470 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| MYL12A | -3398 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| SIAH1 | -3347 |
| SEMA7A | -3299 |
| RPS14 | -3261 |
| PIP5K1C | -3229 |
| SMARCA4 | -3226 |
| EGR2 | -3207 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| ENAH | -3139 |
| SEM1 | -3130 |
| PSMA3 | -3078 |
| GRB2 | -3047 |
| LYN | -3038 |
| RPS6KA3 | -3030 |
| ABL2 | -3020 |
| RPS15A | -3019 |
| ELOB | -3004 |
| DOK6 | -2987 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| PSMD8 | -2928 |
| RPS21 | -2927 |
| AP2S1 | -2922 |
| ARHGEF7 | -2913 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| DSCAML1 | -2830 |
| PIK3CA | -2813 |
| RPS27A | -2773 |
| ROCK2 | -2772 |
| PSMA5 | -2715 |
| DOK4 | -2697 |
| CAP2 | -2694 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| ADAM10 | -2671 |
| RPS18 | -2648 |
| PDLIM7 | -2636 |
| RPL41 | -2635 |
| PIK3CB | -2588 |
| RPS13 | -2581 |
| PSMD13 | -2577 |
| RPL4 | -2563 |
| PSEN2 | -2559 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| PRX | -2432 |
| PSMC2 | -2389 |
| AGRN | -2369 |
| PSME1 | -2348 |
| PSENEN | -2327 |
| PIK3R3 | -2279 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| ARPC2 | -2209 |
| DAG1 | -2174 |
| CDC42 | -2172 |
| NCBP1 | -2151 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| KRAS | -2044 |
| NTN4 | -1999 |
| PSMB3 | -1915 |
| RPL23 | -1913 |
| AP2A1 | -1902 |
| MAPK13 | -1875 |
| SDCBP | -1822 |
| RPL24 | -1804 |
| SRGAP1 | -1796 |
| RPL38 | -1791 |
| SRGAP2 | -1779 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| RBM8A | -1583 |
| RRAS | -1578 |
| ARPC5 | -1511 |
| PSMC3 | -1509 |
| PRKACB | -1429 |
| RND1 | -1410 |
| PIK3R2 | -1355 |
| CDK5 | -1352 |
| YES1 | -1340 |
| RPL15 | -1313 |
| LAMC1 | -1300 |
| EFNA3 | -1228 |
| RPL3 | -1165 |
| RPS6KA2 | -1149 |
| PSMB4 | -1144 |
| RPL17 | -1119 |
| ARHGEF12 | -1086 |
| RPS8 | -1071 |
| PLXNA1 | -1050 |
| PLXNB1 | -1046 |
| HSP90AA1 | -1030 |
| RPL12 | -983 |
| MAGOH | -969 |
| SOS1 | -950 |
| RPS25 | -937 |
| SH3KBP1 | -917 |
| L1CAM | -904 |
| PSMA7 | -892 |
| PTPN11 | -867 |
| PRKAR2A | -860 |
| PSMB5 | -742 |
| RPL13 | -706 |
| MAPK8 | -700 |
| ITGA2B | -688 |
| RELN | -662 |
| NCSTN | -554 |
| RPL5 | -495 |
| GRIN1 | -442 |
| PSMD11 | -432 |
| ADGRG6 | -428 |
| KALRN | -408 |
| HDAC2 | -338 |
| SCN11A | -295 |
| WWTR1 | -271 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| CDK5R1 | -157 |
| RPS27 | -152 |
| PSMA6 | -126 |
| RAC1 | 44 |
| SDC2 | 147 |
| ITSN1 | 159 |
| CNTN2 | 200 |
| SCN8A | 249 |
| MAPK11 | 251 |
| RPL9 | 261 |
| ANK3 | 303 |
| RPL31 | 330 |
| CUL2 | 359 |
| RPS26 | 419 |
| PSMB10 | 423 |
| CREB1 | 474 |
| SHTN1 | 547 |
| ITGA5 | 587 |
| APH1A | 619 |
| ELOC | 645 |
| RPS6KA4 | 731 |
| NAB1 | 765 |
| UBC | 779 |
| PTPRA | 815 |
| SLIT1 | 886 |
| SHANK3 | 935 |
| ARTN | 973 |
| RDX | 1011 |
| MYH11 | 1015 |
| PAK1 | 1031 |
| PSMB1 | 1054 |
| EIF4A3 | 1154 |
| LAMA1 | 1285 |
| RGMB | 1321 |
| GRIN2B | 1330 |
| NRP1 | 1353 |
| RPL21 | 1385 |
| ACTR2 | 1435 |
| NCK1 | 1525 |
| DPYSL4 | 1531 |
| CLASP1 | 1561 |
| LIMK1 | 1565 |
| GAB1 | 1575 |
| EPHA10 | 1725 |
| EFNA2 | 1735 |
| PRKACA | 1736 |
| PSMB2 | 1876 |
| LDB1 | 1882 |
| USP33 | 1924 |
| FYN | 1937 |
| CACNB4 | 1983 |
| ABL1 | 2023 |
| AP2B1 | 2029 |
| COL6A3 | 2085 |
| RPL22 | 2142 |
| YAP1 | 2171 |
| MAPK14 | 2269 |
| NRAS | 2310 |
| UPF3B | 2326 |
| SPTAN1 | 2385 |
| SCN1B | 2398 |
| PRKCA | 2439 |
| EVL | 2467 |
| SCN3B | 2499 |
| PLCG1 | 2511 |
| MYH10 | 2558 |
| RASA1 | 2559 |
| ABLIM3 | 2675 |
| MYL9 | 2704 |
| HOXA2 | 2735 |
| VAV2 | 2817 |
| RPL36A | 2875 |
| MBP | 2888 |
| CACNB1 | 2967 |
| VLDLR | 3001 |
| ARPC1A | 3022 |
| AKAP5 | 3035 |
| RPS6KA5 | 3086 |
| ALCAM | 3171 |
| RGMA | 3210 |
| COL6A2 | 3222 |
| EFNB3 | 3419 |
| EFNB1 | 3480 |
| SCN9A | 3533 |
| DOCK1 | 3540 |
| SCD5 | 3592 |
| TRPC1 | 3602 |
| EFNA4 | 3658 |
| FARP2 | 3688 |
| CACNB3 | 3735 |
| LAMB1 | 3783 |
| ARPC3 | 3797 |
| NRTN | 3870 |
| SPTBN2 | 3883 |
| RPS6KA6 | 3918 |
| SRC | 3962 |
| SEMA3A | 4001 |
| NEO1 | 4016 |
| DOK1 | 4072 |
| PSMD12 | 4303 |
| PLXNC1 | 4319 |
| MSI1 | 4326 |
| GFRA3 | 4393 |
| AGAP2 | 4399 |
| CSNK2B | 4415 |
| TIAM1 | 4452 |
| PSMD4 | 4567 |
| ROBO3 | 4691 |
| PSMD10 | 4933 |
| PSMD7 | 4942 |
| EPHA1 | 4960 |
| DLG4 | 5108 |
| PSMD5 | 5116 |
| ITGA1 | 5152 |
| DLG3 | 5168 |
| GPC1 | 5178 |
| CD24 | 5327 |
| PSMB9 | 5491 |
| MYH14 | 5492 |
| FES | 5506 |
| ERBB2 | 5534 |
| MAGOHB | 5814 |
| PSMD14 | 5974 |
| KIF4A | 6056 |
| RHOB | 6064 |
| APH1B | 6168 |
| ABLIM2 | 6389 |
| LIMK2 | 6394 |
| CLTCL1 | 6404 |
| TEAD1 | 6440 |
| SEMA4D | 6479 |
| DNM1 | 6505 |
| MAPK3 | 6640 |
| GJB1 | 6678 |
| COL4A5 | 6694 |
| CYP51A1 | 6741 |
| SRGAP3 | 6775 |
| NCBP2 | 6823 |
| ADGRV1 | 6861 |
| PFN2 | 6877 |
| NGEF | 7064 |
| COL9A3 | 7151 |
| FLRT3 | 7184 |
| CNTNAP1 | 7239 |
| PMP22 | 7297 |
| SREBF2 | 7304 |
| COL6A1 | 7322 |
| SCN1A | 7327 |
| COL9A2 | 7348 |
| HMGCR | 7355 |
| MPZ | 7386 |
L13a-mediated translational silencing of Ceruloplasmin expression
| 573 | |
|---|---|
| set | L13a-mediated translational silencing of Ceruloplasmin expression |
| setSize | 108 |
| pANOVA | 4.15e-13 |
| s.dist | -0.404 |
| p.adjustANOVA | 5.71e-11 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| EIF4A1 | -6995 |
| RPL36AL | -6981 |
| EIF3A | -6965 |
| EIF4G1 | -5901 |
| EIF4B | -5898 |
| EIF3I | -5279 |
| RPL19 | -5254 |
| EIF2S1 | -5190 |
| RPS7 | -5138 |
| EIF3B | -5127 |
| UBA52 | -5068 |
| EIF4H | -5055 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| EIF3G | -4724 |
| RPS11 | -4702 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| EIF4A1 | -6995 |
| RPL36AL | -6981 |
| EIF3A | -6965 |
| EIF4G1 | -5901 |
| EIF4B | -5898 |
| EIF3I | -5279 |
| RPL19 | -5254 |
| EIF2S1 | -5190 |
| RPS7 | -5138 |
| EIF3B | -5127 |
| UBA52 | -5068 |
| EIF4H | -5055 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| EIF3G | -4724 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| EIF3J | -4539 |
| EIF2S2 | -4458 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| EIF3M | -4358 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| RPL30 | -4081 |
| RPS9 | -4028 |
| RPL18 | -3961 |
| RPL26L1 | -3873 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| EIF3D | -3740 |
| EIF2S3 | -3669 |
| RPL28 | -3546 |
| PABPC1 | -3543 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| RPS15A | -3019 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| RPS27A | -2773 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| EIF3L | -2407 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| EIF3K | -2206 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| RPL23 | -1913 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| RPS25 | -937 |
| EIF3F | -893 |
| RPL13 | -706 |
| RPL5 | -495 |
| EIF3C | -374 |
| EIF1AX | -274 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPS26 | 419 |
| EIF3H | 899 |
| RPL21 | 1385 |
| RPL22 | 2142 |
| EIF4E | 2473 |
| RPL36A | 2875 |
| EIF3E | 3244 |
| EIF4A2 | 5593 |
GTP hydrolysis and joining of the 60S ribosomal subunit
| 416 | |
|---|---|
| set | GTP hydrolysis and joining of the 60S ribosomal subunit |
| setSize | 109 |
| pANOVA | 5.93e-13 |
| s.dist | -0.399 |
| p.adjustANOVA | 6.44e-11 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| EIF4A1 | -6995 |
| RPL36AL | -6981 |
| EIF3A | -6965 |
| EIF5 | -6065 |
| EIF4G1 | -5901 |
| EIF4B | -5898 |
| EIF3I | -5279 |
| RPL19 | -5254 |
| EIF2S1 | -5190 |
| RPS7 | -5138 |
| EIF3B | -5127 |
| UBA52 | -5068 |
| EIF4H | -5055 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| EIF3G | -4724 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| EIF4A1 | -6995 |
| RPL36AL | -6981 |
| EIF3A | -6965 |
| EIF5 | -6065 |
| EIF4G1 | -5901 |
| EIF4B | -5898 |
| EIF3I | -5279 |
| RPL19 | -5254 |
| EIF2S1 | -5190 |
| RPS7 | -5138 |
| EIF3B | -5127 |
| UBA52 | -5068 |
| EIF4H | -5055 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| EIF3G | -4724 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| EIF3J | -4539 |
| EIF2S2 | -4458 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| EIF3M | -4358 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| RPL30 | -4081 |
| RPS9 | -4028 |
| RPL18 | -3961 |
| RPL26L1 | -3873 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| EIF3D | -3740 |
| EIF2S3 | -3669 |
| RPL28 | -3546 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| RPS15A | -3019 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| RPS27A | -2773 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| EIF3L | -2407 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| EIF3K | -2206 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| RPL23 | -1913 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| RPS25 | -937 |
| EIF3F | -893 |
| RPL13 | -706 |
| RPL5 | -495 |
| EIF3C | -374 |
| EIF1AX | -274 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPS26 | 419 |
| EIF3H | 899 |
| RPL21 | 1385 |
| RPL22 | 2142 |
| EIF4E | 2473 |
| RPL36A | 2875 |
| EIF3E | 3244 |
| EIF5B | 3318 |
| EIF4A2 | 5593 |
Developmental Biology
| 268 | |
|---|---|
| set | Developmental Biology |
| setSize | 677 |
| pANOVA | 6e-13 |
| s.dist | -0.163 |
| p.adjustANOVA | 6.44e-11 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| GFI1 | -7110 |
| KLF4 | -7093 |
| VASP | -7075 |
| ABLIM1 | -7055 |
| RUNX1 | -7020 |
| RPL36AL | -6981 |
| ETF1 | -6952 |
| RNPS1 | -6938 |
| TGFB1 | -6934 |
| ARHGEF28 | -6925 |
| SHC1 | -6910 |
| MAML1 | -6891 |
| MET | -6878 |
| RANBP9 | -6871 |
| EPHA2 | -6857 |
| ACTG1 | -6841 |
| GSPT1 | -6825 |
| ANK2 | -6778 |
| SEMA6A | -6761 |
| RHOC | -6747 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| GFI1 | -7110 |
| KLF4 | -7093 |
| VASP | -7075 |
| ABLIM1 | -7055 |
| RUNX1 | -7020 |
| RPL36AL | -6981 |
| ETF1 | -6952 |
| RNPS1 | -6938 |
| TGFB1 | -6934 |
| ARHGEF28 | -6925 |
| SHC1 | -6910 |
| MAML1 | -6891 |
| MET | -6878 |
| RANBP9 | -6871 |
| EPHA2 | -6857 |
| ACTG1 | -6841 |
| GSPT1 | -6825 |
| ANK2 | -6778 |
| SEMA6A | -6761 |
| RHOC | -6747 |
| NCOA6 | -6745 |
| PPARA | -6722 |
| SCN2A | -6712 |
| FURIN | -6683 |
| KRT18 | -6682 |
| SIAH2 | -6666 |
| PSMF1 | -6663 |
| MYL12B | -6653 |
| WASL | -6543 |
| DNM2 | -6535 |
| DPYSL2 | -6519 |
| KMT2C | -6514 |
| KRT8 | -6499 |
| EP300 | -6470 |
| ITGA10 | -6466 |
| PSME4 | -6450 |
| ARHGAP35 | -6446 |
| CLTA | -6439 |
| PSMD2 | -6435 |
| CBFB | -6381 |
| MYL6 | -6380 |
| KAZN | -6374 |
| KLF5 | -6373 |
| NAB2 | -6372 |
| GATA4 | -6369 |
| PLXNA3 | -6318 |
| ARHGAP39 | -6303 |
| PFN1 | -6285 |
| RARA | -6269 |
| KMT2D | -6260 |
| UNC5B | -6252 |
| KRT17 | -6225 |
| CLTC | -6220 |
| ITGA2 | -6205 |
| FGFR1 | -6191 |
| UPF3A | -6189 |
| KDM6A | -6150 |
| TLN1 | -6146 |
| SMAD3 | -6145 |
| PRNP | -6115 |
| ARPC4 | -6094 |
| MAP2K2 | -6087 |
| CLTB | -6064 |
| MEF2D | -5995 |
| CASC3 | -5986 |
| PSMD6 | -5951 |
| MYO9B | -5920 |
| EIF4G1 | -5901 |
| SPAG9 | -5897 |
| PCGF2 | -5881 |
| PPARGC1A | -5869 |
| CAPN1 | -5850 |
| EFNA1 | -5830 |
| PSMA2 | -5801 |
| CFL1 | -5737 |
| PSMA1 | -5730 |
| TDGF1 | -5711 |
| PLXND1 | -5686 |
| CACNA1D | -5676 |
| EZH2 | -5631 |
| PITPNA | -5591 |
| GIT1 | -5582 |
| SNW1 | -5581 |
| ROBO1 | -5577 |
| PSMC1 | -5564 |
| CTNNA1 | -5558 |
| NR5A2 | -5547 |
| HRAS | -5543 |
| MAPK12 | -5538 |
| PSMD3 | -5535 |
| GRB10 | -5504 |
| PSME2 | -5481 |
| POLR2L | -5471 |
| IRS2 | -5461 |
| MED1 | -5451 |
| SOS2 | -5417 |
| EGFR | -5383 |
| PAK4 | -5359 |
| PSMD1 | -5351 |
| TRIO | -5341 |
| NRP2 | -5313 |
| ACTR3 | -5296 |
| RHOA | -5294 |
| MYO10 | -5290 |
| MED13 | -5289 |
| POLR2F | -5283 |
| ZSWIM8 | -5267 |
| ARHGEF11 | -5260 |
| RPL19 | -5254 |
| BNIP2 | -5239 |
| HOXA4 | -5235 |
| NUMB | -5224 |
| YY1 | -5214 |
| PSPN | -5177 |
| EPHB1 | -5141 |
| RPS7 | -5138 |
| GSK3B | -5101 |
| UBA52 | -5068 |
| MAPK1 | -5066 |
| CDK4 | -5064 |
| ACTB | -5057 |
| CSNK2A1 | -5040 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| RAP1GAP | -4998 |
| FAU | -4990 |
| RPL14 | -4978 |
| PAK2 | -4957 |
| IL6R | -4943 |
| PSEN1 | -4938 |
| EPAS1 | -4915 |
| KRT23 | -4907 |
| SPTBN1 | -4901 |
| PSMB6 | -4888 |
| MED26 | -4882 |
| PSMC6 | -4878 |
| POU5F1 | -4823 |
| KRT80 | -4809 |
| PSMC4 | -4808 |
| KAT2B | -4792 |
| RPS5 | -4778 |
| PIK3CD | -4759 |
| MED15 | -4756 |
| DSP | -4746 |
| MYH9 | -4726 |
| RPS11 | -4702 |
| NR5A1 | -4679 |
| MMP2 | -4677 |
| POLR2E | -4667 |
| NCOA1 | -4665 |
| RPS19 | -4661 |
| ANK1 | -4656 |
| HSPA8 | -4654 |
| RPS28 | -4652 |
| VAV3 | -4642 |
| PSMD9 | -4638 |
| MED17 | -4637 |
| CHD9 | -4634 |
| AP2M1 | -4603 |
| CSNK2A2 | -4546 |
| EZR | -4464 |
| ARPC1B | -4429 |
| HSP90AB1 | -4426 |
| KRT19 | -4417 |
| CAPNS1 | -4414 |
| NCOR2 | -4409 |
| RPLP1 | -4391 |
| PAXIP1 | -4383 |
| MAPK7 | -4382 |
| EPHB4 | -4379 |
| PIK3R1 | -4376 |
| NCOR1 | -4374 |
| PSMB7 | -4372 |
| RPS12 | -4367 |
| PTK2 | -4346 |
| NR2F2 | -4332 |
| ITGAV | -4312 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| CDK8 | -4276 |
| UBB | -4263 |
| CLASP2 | -4246 |
| DSG2 | -4228 |
| PSMA4 | -4211 |
| MED13L | -4184 |
| RPL35A | -4159 |
| ITGB1 | -4145 |
| FOXP1 | -4141 |
| GAB2 | -4127 |
| MAP2K1 | -4120 |
| UTRN | -4105 |
| LYPLA2 | -4095 |
| PSMC5 | -4091 |
| SMAD2 | -4087 |
| CAP1 | -4085 |
| RPL30 | -4081 |
| RXRA | -4073 |
| PPP3CB | -4060 |
| RPS9 | -4028 |
| GRB7 | -4006 |
| GDNF | -3969 |
| RPL18 | -3961 |
| NOTCH1 | -3923 |
| NCK2 | -3916 |
| CACNA1H | -3915 |
| CREBBP | -3888 |
| RPL26L1 | -3873 |
| DLG1 | -3865 |
| RPS6KA1 | -3857 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| UPF2 | -3830 |
| NRCAM | -3815 |
| PLXNA2 | -3814 |
| PSME3 | -3813 |
| FRS2 | -3790 |
| CACNG4 | -3785 |
| SHC3 | -3782 |
| PLXNB3 | -3778 |
| RBX1 | -3714 |
| POLR2B | -3699 |
| NR6A1 | -3646 |
| ROCK1 | -3594 |
| POLR2H | -3593 |
| CDKN1A | -3580 |
| SREBF1 | -3554 |
| RPL28 | -3546 |
| PABPC1 | -3543 |
| RPSA | -3520 |
| NFKB1 | -3507 |
| AP2A2 | -3499 |
| THRAP3 | -3489 |
| EFNB2 | -3470 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| POLR2C | -3425 |
| RPL37 | -3413 |
| MYL12A | -3398 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| SIAH1 | -3347 |
| MEF2A | -3308 |
| SEMA7A | -3299 |
| RBBP4 | -3297 |
| RPS14 | -3261 |
| PIP5K1C | -3229 |
| SMARCA4 | -3226 |
| KMT2A | -3225 |
| EGR2 | -3207 |
| MED18 | -3198 |
| RPS27L | -3180 |
| PPARG | -3168 |
| TCF12 | -3164 |
| RPS10 | -3155 |
| PPL | -3149 |
| ENAH | -3139 |
| SEM1 | -3130 |
| PSMA3 | -3078 |
| GRB2 | -3047 |
| LYN | -3038 |
| PKNOX1 | -3036 |
| RPS6KA3 | -3030 |
| ABL2 | -3020 |
| RPS15A | -3019 |
| ELOB | -3004 |
| DOK6 | -2987 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| AKT1 | -2958 |
| JUN | -2934 |
| PSMD8 | -2928 |
| RPS21 | -2927 |
| AP2S1 | -2922 |
| ARHGEF7 | -2913 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| DSCAML1 | -2830 |
| PIK3CA | -2813 |
| RPS27A | -2773 |
| ROCK2 | -2772 |
| MED27 | -2745 |
| PSMA5 | -2715 |
| DOK4 | -2697 |
| CAP2 | -2694 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| CCND3 | -2677 |
| ADAM10 | -2671 |
| RPS18 | -2648 |
| PDLIM7 | -2636 |
| RPL41 | -2635 |
| RELA | -2632 |
| TGM1 | -2621 |
| PIK3CB | -2588 |
| RPS13 | -2581 |
| TFDP1 | -2579 |
| PSMD13 | -2577 |
| RPL4 | -2563 |
| PSEN2 | -2559 |
| CCNC | -2471 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| PRX | -2432 |
| PSMC2 | -2389 |
| STX1A | -2377 |
| AGRN | -2369 |
| MAP2K6 | -2351 |
| DSC2 | -2349 |
| PSME1 | -2348 |
| CDH2 | -2339 |
| PSENEN | -2327 |
| NCOA3 | -2326 |
| PIK3R3 | -2279 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| ARPC2 | -2209 |
| DAG1 | -2174 |
| CDC42 | -2172 |
| CDH15 | -2166 |
| NCBP1 | -2151 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| KRAS | -2044 |
| MED6 | -2003 |
| NTN4 | -1999 |
| ZNF335 | -1966 |
| AKT2 | -1946 |
| PSMB3 | -1915 |
| RPL23 | -1913 |
| AP2A1 | -1902 |
| MAPK13 | -1875 |
| SDCBP | -1822 |
| RPL24 | -1804 |
| PKP4 | -1800 |
| SRGAP1 | -1796 |
| RPL38 | -1791 |
| SRGAP2 | -1779 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| ADAM11 | -1647 |
| TBL1X | -1621 |
| RBM8A | -1583 |
| RRAS | -1578 |
| FOXA2 | -1563 |
| ARPC5 | -1511 |
| PSMC3 | -1509 |
| CDK19 | -1471 |
| MED14 | -1453 |
| PRKACB | -1429 |
| RND1 | -1410 |
| TCF3 | -1396 |
| PIK3R2 | -1355 |
| CDK5 | -1352 |
| MED19 | -1350 |
| YES1 | -1340 |
| RPL15 | -1313 |
| LAMC1 | -1300 |
| GATA2 | -1286 |
| EFNA3 | -1228 |
| RPL3 | -1165 |
| RPS6KA2 | -1149 |
| PSMB4 | -1144 |
| MED10 | -1134 |
| CEBPB | -1129 |
| RPL17 | -1119 |
| ARHGEF12 | -1086 |
| RPS8 | -1071 |
| PLXNA1 | -1050 |
| PLXNB1 | -1046 |
| HSP90AA1 | -1030 |
| RPL12 | -983 |
| MAGOH | -969 |
| SOS1 | -950 |
| RPS25 | -937 |
| SH3KBP1 | -917 |
| L1CAM | -904 |
| PSMA7 | -892 |
| HNF4G | -890 |
| PTPN11 | -867 |
| PRKAR2A | -860 |
| PSMB5 | -742 |
| MED21 | -723 |
| MED24 | -715 |
| RPL13 | -706 |
| MAPK8 | -700 |
| ITGA2B | -688 |
| RELN | -662 |
| POLR2J | -603 |
| MAFA | -561 |
| NCSTN | -554 |
| RPL5 | -495 |
| PAX6 | -478 |
| GRIN1 | -442 |
| PSMD11 | -432 |
| ADGRG6 | -428 |
| KALRN | -408 |
| HDAC2 | -338 |
| SCN11A | -295 |
| WWTR1 | -271 |
| RPL22L1 | -214 |
| DSC3 | -202 |
| RPS3A | -179 |
| CDK5R1 | -157 |
| RPS27 | -152 |
| PSMA6 | -126 |
| HNF4A | -121 |
| RBBP5 | -101 |
| HDAC3 | 38 |
| RAC1 | 44 |
| WT1 | 114 |
| SDC2 | 147 |
| MED8 | 157 |
| ITSN1 | 159 |
| RARG | 173 |
| CNTN2 | 200 |
| PKP3 | 204 |
| SCN8A | 249 |
| MAPK11 | 251 |
| RPL9 | 261 |
| ANK3 | 303 |
| RPL31 | 330 |
| MED31 | 341 |
| SUZ12 | 346 |
| CUL2 | 359 |
| PIAS2 | 388 |
| RPS26 | 419 |
| PSMB10 | 423 |
| CREB1 | 474 |
| SHTN1 | 547 |
| ITGA5 | 587 |
| MED16 | 610 |
| APH1A | 619 |
| ELOC | 645 |
| RPS6KA4 | 731 |
| CNOT6 | 732 |
| NAB1 | 765 |
| ACVR2A | 775 |
| UBC | 779 |
| HNF1A | 783 |
| PTPRA | 815 |
| PBX1 | 827 |
| SLIT1 | 886 |
| HNF1B | 912 |
| HHEX | 922 |
| ACVR2B | 931 |
| SHANK3 | 935 |
| ARTN | 973 |
| RDX | 1011 |
| MYH11 | 1015 |
| SLC2A4 | 1030 |
| PAK1 | 1031 |
| PML | 1051 |
| PSMB1 | 1054 |
| EIF4A3 | 1154 |
| HOXD1 | 1160 |
| NANOG | 1164 |
| CACNG8 | 1174 |
| KRT15 | 1181 |
| ONECUT3 | 1186 |
| MED25 | 1246 |
| SALL1 | 1265 |
| LAMA1 | 1285 |
| RGMB | 1321 |
| ZNF638 | 1329 |
| GRIN2B | 1330 |
| NRP1 | 1353 |
| RPL21 | 1385 |
| ZFPM2 | 1391 |
| TBL1XR1 | 1404 |
| ACTR2 | 1435 |
| PKP2 | 1490 |
| NCK1 | 1525 |
| DPYSL4 | 1531 |
| CLASP1 | 1561 |
| LIMK1 | 1565 |
| GAB1 | 1575 |
| PAGR1 | 1634 |
| EPHA10 | 1725 |
| EFNA2 | 1735 |
| PRKACA | 1736 |
| ADAM22 | 1805 |
| STX1B | 1841 |
| PSMB2 | 1876 |
| LDB1 | 1882 |
| MYC | 1892 |
| USP33 | 1924 |
| FYN | 1937 |
| ST14 | 1967 |
| CACNB4 | 1983 |
| POLR2G | 2003 |
| ABL1 | 2023 |
| AP2B1 | 2029 |
| COL6A3 | 2085 |
| RPL22 | 2142 |
| TGS1 | 2148 |
| YAP1 | 2171 |
| MED28 | 2239 |
| MAPK14 | 2269 |
| FOXO3 | 2282 |
| SMARCD3 | 2305 |
| NRAS | 2310 |
| JUP | 2314 |
| UPF3B | 2326 |
| EED | 2369 |
| SPTAN1 | 2385 |
| SCN1B | 2398 |
| POLR2D | 2418 |
| FOXA3 | 2431 |
| PRKCA | 2439 |
| EVL | 2467 |
| GATA6 | 2495 |
| SCN3B | 2499 |
| PLCG1 | 2511 |
| MYH10 | 2558 |
| RASA1 | 2559 |
| WDR5 | 2561 |
| CDON | 2669 |
| ABLIM3 | 2675 |
| MYL9 | 2704 |
| POLR2A | 2705 |
| SPINK9 | 2709 |
| HOXA2 | 2735 |
| SMAD4 | 2742 |
| VAV2 | 2817 |
| KRT10 | 2866 |
| RPL36A | 2875 |
| MBP | 2888 |
| CSTA | 2890 |
| MED4 | 2904 |
| MED23 | 2950 |
| CACNB1 | 2967 |
| DRAP1 | 2970 |
| CEBPA | 3000 |
| VLDLR | 3001 |
| ARPC1A | 3022 |
| AKAP5 | 3035 |
| RPS6KA5 | 3086 |
| ALCAM | 3171 |
| RGMA | 3210 |
| COL6A2 | 3222 |
| CTNNB1 | 3272 |
| EFNB3 | 3419 |
| EFNB1 | 3480 |
| MED12 | 3501 |
| CARM1 | 3517 |
| SCN9A | 3533 |
| DOCK1 | 3540 |
| SCD5 | 3592 |
| TRPC1 | 3602 |
| DPPA4 | 3619 |
| EFNA4 | 3658 |
| FARP2 | 3688 |
| CACNB3 | 3735 |
| PLIN1 | 3775 |
| LAMB1 | 3783 |
| ARPC3 | 3797 |
| NRTN | 3870 |
| SPTBN2 | 3883 |
| RPS6KA6 | 3918 |
| SRC | 3962 |
| SEMA3A | 4001 |
| NEO1 | 4016 |
| TSC22D1 | 4059 |
| DOK1 | 4072 |
| CDK2 | 4114 |
| STAT3 | 4253 |
| PSMD12 | 4303 |
| PLXNC1 | 4319 |
| MSI1 | 4326 |
| GFRA3 | 4393 |
| AGAP2 | 4399 |
| ACVR1B | 4400 |
| DKK1 | 4410 |
| CSNK2B | 4415 |
| HIF3A | 4444 |
| TIAM1 | 4452 |
| MEF2B | 4564 |
| PSMD4 | 4567 |
| MED11 | 4574 |
| DEK | 4581 |
| POLR2I | 4594 |
| PERP | 4630 |
| ROBO3 | 4691 |
| ASH2L | 4729 |
| NCOA2 | 4780 |
| HELZ2 | 4786 |
| RBPJ | 4794 |
| MED9 | 4847 |
| TFDP2 | 4856 |
| PSMD10 | 4933 |
| PSMD7 | 4942 |
| FAM120B | 4955 |
| EPHA1 | 4960 |
| CTCF | 4990 |
| GDF1 | 5042 |
| KAT2A | 5077 |
| DLG4 | 5108 |
| PSMD5 | 5116 |
| RBBP7 | 5134 |
| ITGA1 | 5152 |
| DLG3 | 5168 |
| GPC1 | 5178 |
| CD36 | 5264 |
| ONECUT1 | 5291 |
| PCSK6 | 5326 |
| CD24 | 5327 |
| H2AFX | 5356 |
| FOXO1 | 5418 |
| SRY | 5473 |
| PSMB9 | 5491 |
| MYH14 | 5492 |
| FES | 5506 |
| MEIS1 | 5510 |
| ERBB2 | 5534 |
| MED20 | 5621 |
| MED30 | 5637 |
| LEFTY2 | 5686 |
| MED7 | 5750 |
| PDX1 | 5812 |
| MAGOHB | 5814 |
| POLR2K | 5962 |
| PSMD14 | 5974 |
| AJUBA | 6013 |
| KIF4A | 6056 |
| RHOB | 6064 |
| MED22 | 6131 |
| APH1B | 6168 |
| ABLIM2 | 6389 |
| LIMK2 | 6394 |
| CLTCL1 | 6404 |
| MED29 | 6433 |
| TEAD1 | 6440 |
| SEMA4D | 6479 |
| DNM1 | 6505 |
| PCK1 | 6525 |
| MAPK3 | 6640 |
| HOXA3 | 6669 |
| GJB1 | 6678 |
| COL4A5 | 6694 |
| CYP51A1 | 6741 |
| SRGAP3 | 6775 |
| NCBP2 | 6823 |
| MAML2 | 6847 |
| ADGRV1 | 6861 |
| CEBPD | 6867 |
| PFN2 | 6877 |
| SALL4 | 6934 |
| ANGPTL4 | 6953 |
| EVPL | 7038 |
| NGEF | 7064 |
| E2F1 | 7096 |
| SOX9 | 7103 |
| COL9A3 | 7151 |
| FLRT3 | 7184 |
| CNTNAP1 | 7239 |
| SLC2A2 | 7259 |
| HES1 | 7265 |
| PMP22 | 7297 |
| SREBF2 | 7304 |
| PKLR | 7311 |
| COL6A1 | 7322 |
| SCN1A | 7327 |
| COL9A2 | 7348 |
| CSF3R | 7351 |
| PRSS8 | 7354 |
| HMGCR | 7355 |
| MPZ | 7386 |
Signal Transduction
| 1072 | |
|---|---|
| set | Signal Transduction |
| setSize | 1748 |
| pANOVA | 6.08e-13 |
| s.dist | -0.106 |
| p.adjustANOVA | 6.44e-11 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SEL1L | -7124 |
| ATP2A2 | -7119 |
| MTMR4 | -7109 |
| SYVN1 | -7108 |
| TMED2 | -7071 |
| ATP6V0B | -7064 |
| ARRB1 | -7062 |
| PGF | -7053 |
| DERL2 | -7046 |
| RAMP1 | -7037 |
| SHB | -7035 |
| CX3CL1 | -7031 |
| RUNX1 | -7020 |
| SQSTM1 | -7010 |
| RRAGC | -7009 |
| STEAP3 | -6993 |
| GPER1 | -6992 |
| OS9 | -6986 |
| ATP6V0A1 | -6979 |
| ARHGEF2 | -6977 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SEL1L | -7124 |
| ATP2A2 | -7119 |
| MTMR4 | -7109 |
| SYVN1 | -7108 |
| TMED2 | -7071 |
| ATP6V0B | -7064 |
| ARRB1 | -7062 |
| PGF | -7053 |
| DERL2 | -7046 |
| RAMP1 | -7037 |
| SHB | -7035 |
| CX3CL1 | -7031 |
| RUNX1 | -7020 |
| SQSTM1 | -7010 |
| RRAGC | -7009 |
| STEAP3 | -6993 |
| GPER1 | -6992 |
| OS9 | -6986 |
| ATP6V0A1 | -6979 |
| ARHGEF2 | -6977 |
| PEBP1 | -6972 |
| RHOQ | -6969 |
| DVL3 | -6967 |
| AMOTL2 | -6961 |
| PIK3AP1 | -6957 |
| JAG1 | -6948 |
| TGFB1 | -6934 |
| CCR6 | -6932 |
| F2RL1 | -6927 |
| BCAR1 | -6926 |
| ARHGEF28 | -6925 |
| ATP6V1D | -6922 |
| SHC1 | -6910 |
| ATP6V0D1 | -6908 |
| ARHGAP32 | -6905 |
| MAML1 | -6891 |
| CCL20 | -6885 |
| P4HB | -6884 |
| ATP6V0A2 | -6880 |
| MET | -6878 |
| RANBP9 | -6871 |
| VGF | -6864 |
| EPHA2 | -6857 |
| SFPQ | -6854 |
| DAGLA | -6851 |
| ACTG1 | -6841 |
| GOLGA3 | -6836 |
| FLNA | -6833 |
| HNRNPM | -6829 |
| BCL9L | -6828 |
| PDGFRB | -6820 |
| SEC13 | -6812 |
| ST3GAL4 | -6801 |
| TRIB3 | -6798 |
| PPP1R15A | -6783 |
| RHOC | -6747 |
| RRAGD | -6743 |
| PTPN3 | -6738 |
| HNRNPF | -6735 |
| VCP | -6720 |
| RAPGEF2 | -6716 |
| FURIN | -6683 |
| FOSL1 | -6672 |
| ACTN1 | -6670 |
| DDX5 | -6665 |
| PSMF1 | -6663 |
| NUDC | -6662 |
| EMC3 | -6661 |
| MYL12B | -6653 |
| TNFRSF10B | -6645 |
| RHOBTB3 | -6640 |
| TFRC | -6637 |
| KIF5A | -6634 |
| ATP6V0E1 | -6622 |
| AKAP13 | -6600 |
| DLC1 | -6599 |
| GNA13 | -6594 |
| RAPGEF1 | -6586 |
| PRKCZ | -6584 |
| VEGFB | -6562 |
| NF2 | -6559 |
| TCF7 | -6556 |
| RALA | -6548 |
| WASL | -6543 |
| DUSP3 | -6541 |
| ESYT1 | -6539 |
| DNM2 | -6535 |
| VRK2 | -6520 |
| CD55 | -6517 |
| ANKLE2 | -6513 |
| APP | -6492 |
| VHL | -6491 |
| TLE4 | -6478 |
| EP300 | -6470 |
| MAPKAPK2 | -6461 |
| PSME4 | -6450 |
| ARHGAP35 | -6446 |
| RXFP4 | -6443 |
| CLTA | -6439 |
| NFKBIA | -6437 |
| PSMD2 | -6435 |
| ADRA2C | -6434 |
| CAMKK1 | -6422 |
| P2RY11 | -6403 |
| PDE4D | -6396 |
| POGLUT1 | -6385 |
| CBFB | -6381 |
| MYL6 | -6380 |
| KDM3A | -6378 |
| NAB2 | -6372 |
| FNBP1 | -6371 |
| TMEM59 | -6370 |
| MIS12 | -6367 |
| HEBP1 | -6361 |
| BCL2L1 | -6349 |
| CDC42EP4 | -6344 |
| BAIAP2L1 | -6338 |
| PIP4K2C | -6335 |
| DNAJB1 | -6326 |
| ARHGAP39 | -6303 |
| ABHD12 | -6295 |
| PFN1 | -6285 |
| FNTA | -6282 |
| TAX1BP1 | -6281 |
| LRIG1 | -6280 |
| GNA12 | -6278 |
| ATP6V1E1 | -6271 |
| RARA | -6269 |
| KMT2D | -6260 |
| KDM4A | -6254 |
| LCK | -6250 |
| MAPK6 | -6249 |
| RBBP6 | -6244 |
| ATP6AP1 | -6235 |
| SMURF1 | -6229 |
| CLTC | -6220 |
| FZD9 | -6213 |
| SH3RF1 | -6212 |
| DGKZ | -6208 |
| ITGA2 | -6205 |
| PTPRK | -6199 |
| SPEN | -6197 |
| PLCB1 | -6196 |
| PRDM4 | -6194 |
| FGFR1 | -6191 |
| ABHD17A | -6185 |
| ATF2 | -6175 |
| ERLEC1 | -6168 |
| PARD3 | -6165 |
| TLN1 | -6146 |
| SMAD3 | -6145 |
| SHMT2 | -6143 |
| RDH10 | -6134 |
| BCAP31 | -6129 |
| DAB2IP | -6128 |
| BAD | -6118 |
| PTPRJ | -6103 |
| LATS2 | -6101 |
| ARPC4 | -6094 |
| FOSB | -6091 |
| ITCH | -6089 |
| ITPR3 | -6088 |
| MAP2K2 | -6087 |
| ATP6V0C | -6086 |
| ADM2 | -6068 |
| CYLD | -6066 |
| CLTB | -6064 |
| KIDINS220 | -6056 |
| MYLIP | -6047 |
| PTHLH | -6042 |
| PTBP1 | -6035 |
| STARD13 | -6024 |
| RAB9A | -6014 |
| MEF2D | -5995 |
| MFN2 | -5992 |
| DDRGK1 | -5991 |
| AKT1S1 | -5990 |
| RRAD | -5988 |
| DGKE | -5985 |
| DUSP4 | -5977 |
| SLC1A5 | -5969 |
| RASGRF2 | -5955 |
| ZDHHC7 | -5954 |
| PSMD6 | -5951 |
| CLIP1 | -5947 |
| IKBKG | -5946 |
| LETM1 | -5941 |
| CDC42BPA | -5937 |
| MAPKAP1 | -5936 |
| SPATA13 | -5931 |
| ATP6V1C2 | -5929 |
| CCT2 | -5926 |
| BCL9 | -5924 |
| MYO9B | -5920 |
| GNA11 | -5916 |
| EIF4G1 | -5901 |
| USF2 | -5900 |
| EIF4B | -5898 |
| ZRANB1 | -5895 |
| SIN3A | -5884 |
| SPP1 | -5872 |
| CCT6A | -5862 |
| CXXC5 | -5859 |
| MEMO1 | -5843 |
| HTR7 | -5841 |
| ADAM17 | -5836 |
| RTKN | -5834 |
| KIF2A | -5815 |
| RAB7A | -5810 |
| FKBP4 | -5807 |
| DIAPH1 | -5806 |
| PDE3A | -5805 |
| AGO3 | -5803 |
| PSMA2 | -5801 |
| WHAMM | -5798 |
| CXCL16 | -5783 |
| RIPK2 | -5779 |
| DYNC2H1 | -5775 |
| MAPKAPK3 | -5773 |
| AXIN2 | -5745 |
| ZNRF3 | -5742 |
| PPP2R5A | -5740 |
| CFL1 | -5737 |
| PPM1A | -5736 |
| ELK1 | -5733 |
| NET1 | -5731 |
| PSMA1 | -5730 |
| WASF1 | -5712 |
| RCC2 | -5709 |
| CBL | -5708 |
| MAF1 | -5705 |
| TOR1AIP1 | -5699 |
| MKRN1 | -5695 |
| PLXND1 | -5686 |
| SNAP23 | -5681 |
| STAT1 | -5668 |
| SOWAHC | -5665 |
| IQGAP1 | -5663 |
| NDEL1 | -5652 |
| CRK | -5650 |
| DLG5 | -5644 |
| PRKCD | -5638 |
| ARHGAP42 | -5635 |
| EZH2 | -5631 |
| MTA2 | -5619 |
| YBX1 | -5615 |
| RGL1 | -5600 |
| ECE1 | -5583 |
| GIT1 | -5582 |
| SNW1 | -5581 |
| ATP6V1B2 | -5574 |
| DUSP5 | -5568 |
| DUSP1 | -5567 |
| PSMC1 | -5564 |
| CTNNA1 | -5558 |
| RAF1 | -5557 |
| CASP10 | -5555 |
| NR5A2 | -5547 |
| HRAS | -5543 |
| SLC38A9 | -5539 |
| MAPK12 | -5538 |
| PSMD3 | -5535 |
| AGO2 | -5530 |
| RGS14 | -5515 |
| FAM13B | -5513 |
| PRKCE | -5510 |
| MADD | -5505 |
| GRB10 | -5504 |
| ZDHHC9 | -5497 |
| SH3PXD2A | -5496 |
| PIP4K2A | -5495 |
| DKK4 | -5490 |
| CDC42EP2 | -5487 |
| PSME2 | -5481 |
| SHC2 | -5479 |
| POLR2L | -5471 |
| AATF | -5468 |
| SOCS6 | -5467 |
| IRS2 | -5461 |
| MED1 | -5451 |
| NCF2 | -5438 |
| BRK1 | -5431 |
| USP2 | -5430 |
| KIF5B | -5426 |
| TMEM87A | -5423 |
| SOS2 | -5417 |
| TRIM33 | -5413 |
| SP1 | -5412 |
| PLIN3 | -5406 |
| ARF6 | -5404 |
| EGFR | -5383 |
| ARHGDIA | -5377 |
| GRIN2D | -5370 |
| STRN | -5363 |
| PAK4 | -5359 |
| CDC42BPB | -5357 |
| ATP6V1G1 | -5352 |
| PSMD1 | -5351 |
| CSNK1A1 | -5349 |
| TRIO | -5341 |
| PTPN12 | -5326 |
| IQGAP2 | -5323 |
| LAMA3 | -5316 |
| NRP2 | -5313 |
| CHN2 | -5305 |
| PDE3B | -5303 |
| STX5 | -5300 |
| RIT1 | -5298 |
| ACTR3 | -5296 |
| RHOA | -5294 |
| LAMTOR5 | -5293 |
| POLR2F | -5283 |
| DUSP10 | -5271 |
| ARHGEF11 | -5260 |
| CASP3 | -5257 |
| SMURF2 | -5253 |
| FSTL3 | -5252 |
| CASP9 | -5247 |
| ARAF | -5242 |
| NUMB | -5224 |
| RBMX | -5221 |
| PIK3C3 | -5220 |
| PSAP | -5218 |
| YY1 | -5214 |
| RAP1GDS1 | -5198 |
| FKBP1A | -5189 |
| CDC37 | -5178 |
| PSPN | -5177 |
| FOS | -5174 |
| PPP2CA | -5168 |
| COPS2 | -5161 |
| PPP1CA | -5153 |
| WWP2 | -5151 |
| KDM4C | -5149 |
| SLK | -5147 |
| PPP2R5B | -5131 |
| SAMM50 | -5117 |
| MXD4 | -5116 |
| PTENP1 | -5107 |
| GSK3B | -5101 |
| DBN1 | -5099 |
| INSR | -5097 |
| AAMP | -5076 |
| PDGFC | -5072 |
| UBA52 | -5068 |
| MAPK1 | -5066 |
| CDK4 | -5064 |
| PLEKHG2 | -5061 |
| ACTB | -5057 |
| CSNK2A1 | -5040 |
| PHLPP1 | -5029 |
| ZAP70 | -5027 |
| TSC1 | -5024 |
| TNFRSF10D | -5009 |
| TLE3 | -5003 |
| PDHX | -4992 |
| CTBP2 | -4982 |
| RRAS2 | -4979 |
| ETV4 | -4971 |
| JAK1 | -4963 |
| PAK2 | -4957 |
| CAB39 | -4956 |
| ARHGAP23 | -4953 |
| ALDH1A1 | -4952 |
| ATP6V1C1 | -4946 |
| ECT2 | -4944 |
| IL6R | -4943 |
| PSEN1 | -4938 |
| FAM135A | -4927 |
| ATF1 | -4925 |
| FRAT2 | -4922 |
| PHB | -4920 |
| EPAS1 | -4915 |
| NOS3 | -4903 |
| SPTBN1 | -4901 |
| YKT6 | -4899 |
| VAPA | -4898 |
| RGS3 | -4893 |
| PSMB6 | -4888 |
| PLTP | -4883 |
| PSMC6 | -4878 |
| PDE8A | -4877 |
| SNX3 | -4858 |
| WNT7B | -4849 |
| AREG | -4847 |
| VPS26A | -4841 |
| TRIM27 | -4835 |
| CHD4 | -4830 |
| RRAGB | -4819 |
| ARFGAP3 | -4817 |
| PSMC4 | -4808 |
| TNRC6C | -4805 |
| TJP1 | -4801 |
| KAT2B | -4792 |
| TNKS | -4790 |
| PIK3CD | -4759 |
| IGF2BP1 | -4754 |
| SH2B3 | -4752 |
| BRAF | -4749 |
| DSP | -4746 |
| PPP2R1A | -4744 |
| HMOX2 | -4742 |
| PKN1 | -4731 |
| ACBD5 | -4727 |
| MYH9 | -4726 |
| PTEN | -4721 |
| MST1 | -4720 |
| CCNT1 | -4690 |
| CDC73 | -4683 |
| MMP2 | -4677 |
| SNAI1 | -4674 |
| ZNF512B | -4669 |
| POLR2E | -4667 |
| NCOA1 | -4665 |
| KDM1B | -4647 |
| RTN4 | -4643 |
| VAV3 | -4642 |
| FAF2 | -4640 |
| PSMD9 | -4638 |
| LRP6 | -4613 |
| EEPD1 | -4610 |
| GNAI3 | -4609 |
| AP2M1 | -4603 |
| CHD8 | -4588 |
| KPNA2 | -4575 |
| ALDH3A2 | -4574 |
| B9D2 | -4569 |
| SPPL2A | -4568 |
| CSNK2A2 | -4546 |
| ROR1 | -4544 |
| MBD3 | -4543 |
| PEAK1 | -4528 |
| GPS2 | -4524 |
| PPP2CB | -4523 |
| GNB2 | -4514 |
| TGFA | -4511 |
| ARAP3 | -4484 |
| ABI1 | -4478 |
| ARHGAP5 | -4477 |
| SEH1L | -4472 |
| DAAM1 | -4459 |
| VEGFA | -4456 |
| USP34 | -4441 |
| TIAL1 | -4432 |
| ARPC1B | -4429 |
| HSP90AB1 | -4426 |
| ATP6V1H | -4423 |
| ARHGAP21 | -4412 |
| NCOR2 | -4409 |
| WNT2B | -4408 |
| HBEGF | -4402 |
| TNFRSF10A | -4397 |
| MAPK7 | -4382 |
| PIK3R1 | -4376 |
| NCOR1 | -4374 |
| PSMB7 | -4372 |
| MCHR1 | -4371 |
| CBX8 | -4370 |
| MIB2 | -4356 |
| PTK2 | -4346 |
| USP15 | -4344 |
| UBE2M | -4337 |
| ITPR1 | -4321 |
| USP9X | -4318 |
| ITGAV | -4312 |
| RACK1 | -4287 |
| PRMT1 | -4281 |
| PHC1 | -4280 |
| CDK8 | -4276 |
| MAP3K11 | -4272 |
| UBB | -4263 |
| IHH | -4252 |
| ATN1 | -4249 |
| CLASP2 | -4246 |
| TMED5 | -4243 |
| RGS12 | -4241 |
| DSG2 | -4228 |
| CYP26B1 | -4218 |
| AXIN1 | -4215 |
| TNRC6B | -4212 |
| PSMA4 | -4211 |
| HGS | -4210 |
| IQCE | -4208 |
| SH3GL1 | -4200 |
| BMI1 | -4180 |
| PPP3R1 | -4176 |
| SFN | -4169 |
| TWF1 | -4167 |
| HIF1A | -4165 |
| P2RY2 | -4163 |
| MCAM | -4158 |
| VANGL1 | -4152 |
| ITGB1 | -4145 |
| STRAP | -4142 |
| CUL1 | -4129 |
| UHRF1BP1L | -4128 |
| GAB2 | -4127 |
| PPP1R12B | -4126 |
| MAP2K1 | -4120 |
| PPID | -4119 |
| CSK | -4113 |
| GATAD2A | -4108 |
| FMNL2 | -4100 |
| PSMC5 | -4091 |
| SMAD2 | -4087 |
| WDR81 | -4080 |
| TXNL1 | -4076 |
| RXRA | -4073 |
| AHCTF1 | -4070 |
| CBX4 | -4063 |
| PPP3CB | -4060 |
| NOX3 | -4056 |
| ZW10 | -4054 |
| MAPKAPK5 | -4050 |
| ECE2 | -4044 |
| HDAC5 | -4034 |
| DAGLB | -4017 |
| FGF17 | -4015 |
| CRABP2 | -4007 |
| GRB7 | -4006 |
| NR3C1 | -4005 |
| UBE2D3 | -3997 |
| MARK3 | -3996 |
| SPINT1 | -3991 |
| EGR3 | -3972 |
| GDNF | -3969 |
| CKAP4 | -3939 |
| ARHGEF16 | -3936 |
| PHLPP2 | -3934 |
| NOTCH1 | -3923 |
| BAIAP2L2 | -3920 |
| NCK2 | -3916 |
| SPRED3 | -3905 |
| GNAI2 | -3904 |
| RPS6KB2 | -3901 |
| DYNC1LI2 | -3897 |
| TNS3 | -3893 |
| CREBBP | -3888 |
| TAB2 | -3878 |
| DUSP7 | -3870 |
| DLG1 | -3865 |
| HEY1 | -3864 |
| PGRMC2 | -3863 |
| RPS6KA1 | -3857 |
| BCL2L11 | -3834 |
| GFOD1 | -3825 |
| ARHGEF5 | -3818 |
| PSME3 | -3813 |
| MFN1 | -3811 |
| STK38 | -3810 |
| PTPN2 | -3809 |
| KLB | -3807 |
| FAM91A1 | -3805 |
| MAPRE1 | -3795 |
| FRS2 | -3790 |
| SHC3 | -3782 |
| ATP6V1A | -3777 |
| PLCG2 | -3766 |
| NUP98 | -3764 |
| RHEB | -3762 |
| FGFRL1 | -3751 |
| SOX4 | -3727 |
| TNS4 | -3726 |
| GNAZ | -3724 |
| RBX1 | -3714 |
| GPHA2 | -3711 |
| POLR2B | -3699 |
| FERMT2 | -3698 |
| LAT | -3697 |
| UHMK1 | -3687 |
| GSK3A | -3684 |
| MTOR | -3683 |
| PARD6B | -3675 |
| APOE | -3670 |
| GALR2 | -3664 |
| SKIL | -3659 |
| TGFBR2 | -3644 |
| WDR83 | -3643 |
| PPP1CB | -3630 |
| RPS6KB1 | -3622 |
| ARHGEF25 | -3620 |
| SH2B1 | -3615 |
| DYNC1H1 | -3614 |
| CPNE8 | -3609 |
| ROCK1 | -3594 |
| POLR2H | -3593 |
| RDH14 | -3592 |
| TRRAP | -3581 |
| CDKN1A | -3580 |
| UCN2 | -3575 |
| STIP1 | -3571 |
| SREBF1 | -3554 |
| JUNB | -3526 |
| YWHAH | -3511 |
| NFKB1 | -3507 |
| GPS1 | -3506 |
| EMD | -3504 |
| AP2A2 | -3499 |
| RCOR1 | -3493 |
| GRAP | -3478 |
| LMAN1 | -3431 |
| POLR2C | -3425 |
| GOLGA7 | -3421 |
| GRK3 | -3418 |
| KHDRBS3 | -3395 |
| PPP1CC | -3392 |
| DTX2 | -3377 |
| DUSP6 | -3376 |
| KLC2 | -3375 |
| WASF2 | -3366 |
| CHUK | -3364 |
| STBD1 | -3361 |
| HSPB1 | -3343 |
| STAG1 | -3341 |
| TAOK3 | -3324 |
| CHD1 | -3315 |
| MEF2A | -3308 |
| SHH | -3305 |
| RBBP4 | -3297 |
| SPOP | -3272 |
| TIAM2 | -3267 |
| ST3GAL6 | -3252 |
| ARRB2 | -3248 |
| LATS1 | -3238 |
| GNB1 | -3237 |
| PIP5K1C | -3229 |
| GALNT3 | -3227 |
| SMARCA4 | -3226 |
| KTN1 | -3223 |
| TNKS2 | -3213 |
| SAV1 | -3212 |
| EGR2 | -3207 |
| TAS1R3 | -3182 |
| PPARG | -3168 |
| TCF12 | -3164 |
| E2F4 | -3153 |
| STK11 | -3146 |
| SPHK1 | -3142 |
| SEM1 | -3130 |
| FN1 | -3115 |
| GNRH1 | -3111 |
| GTF2F1 | -3103 |
| SWAP70 | -3097 |
| SRF | -3090 |
| LEO1 | -3088 |
| ANOS1 | -3087 |
| PSMA3 | -3078 |
| CUL3 | -3056 |
| PRKAA2 | -3053 |
| GRB2 | -3047 |
| PDE4A | -3039 |
| LYN | -3038 |
| RPS6KA3 | -3030 |
| KCTD13 | -3029 |
| ARHGAP17 | -3026 |
| ABL2 | -3020 |
| RGL2 | -3017 |
| CKB | -3007 |
| VPS35 | -3006 |
| KISS1 | -2999 |
| ARHGAP26 | -2989 |
| NPW | -2970 |
| WIPF2 | -2965 |
| AKT1 | -2958 |
| JUN | -2934 |
| IKBKB | -2931 |
| XIAP | -2929 |
| PSMD8 | -2928 |
| AP2S1 | -2922 |
| ARHGEF7 | -2913 |
| ARMCX3 | -2911 |
| PELP1 | -2894 |
| RBCK1 | -2891 |
| RIPK1 | -2886 |
| AKAP12 | -2868 |
| TAOK1 | -2864 |
| SPRED2 | -2862 |
| USP8 | -2820 |
| ADCY6 | -2818 |
| PIK3CA | -2813 |
| TLE1 | -2800 |
| FGFR4 | -2795 |
| NCKAP1 | -2788 |
| DYNC1I2 | -2780 |
| ELMO1 | -2779 |
| RPS27A | -2773 |
| ROCK2 | -2772 |
| RHOG | -2756 |
| IGF1R | -2746 |
| JAK2 | -2719 |
| PSMA5 | -2715 |
| PPP3CC | -2712 |
| GPR35 | -2701 |
| RPS6 | -2681 |
| CCND3 | -2677 |
| HDAC1 | -2676 |
| ADAM10 | -2671 |
| WNT3 | -2666 |
| PDGFA | -2660 |
| SSTR2 | -2650 |
| SCRIB | -2641 |
| RELA | -2632 |
| LAMTOR3 | -2631 |
| GPR143 | -2627 |
| TGFBR1 | -2620 |
| STAG2 | -2617 |
| AXL | -2605 |
| RHOF | -2600 |
| MTX1 | -2595 |
| PIK3CB | -2588 |
| ARC | -2587 |
| TFDP1 | -2579 |
| PSMD13 | -2577 |
| SPRED1 | -2574 |
| FBXW7 | -2564 |
| PSEN2 | -2559 |
| DGKD | -2554 |
| FNTB | -2551 |
| ADM | -2543 |
| RYK | -2525 |
| RHOJ | -2522 |
| DYNC1LI1 | -2519 |
| SIRT6 | -2510 |
| BCR | -2502 |
| OTULIN | -2499 |
| GNAI1 | -2495 |
| TAX1BP3 | -2489 |
| CCNC | -2471 |
| TSC2 | -2462 |
| ALDH1A2 | -2454 |
| MAP2K5 | -2441 |
| PMF1 | -2433 |
| MSI2 | -2422 |
| PLCB3 | -2412 |
| FMNL1 | -2403 |
| FST | -2393 |
| PSMC2 | -2389 |
| TLR9 | -2371 |
| ESRP2 | -2361 |
| PSME1 | -2348 |
| OTUD3 | -2342 |
| MKNK1 | -2340 |
| PSENEN | -2327 |
| NCOA3 | -2326 |
| INHBB | -2320 |
| LRP5 | -2319 |
| ERBIN | -2316 |
| NELFB | -2298 |
| ABCA1 | -2289 |
| PIK3R3 | -2279 |
| DVL1 | -2264 |
| CFLAR | -2258 |
| CPSF7 | -2243 |
| OSBPL11 | -2229 |
| PDK3 | -2228 |
| IRAK1 | -2218 |
| ARPC2 | -2209 |
| USF1 | -2194 |
| CDC42 | -2172 |
| ARHGAP9 | -2170 |
| CCDC88C | -2163 |
| NCBP1 | -2151 |
| RAB4A | -2148 |
| PPP2R5D | -2117 |
| GPSM3 | -2116 |
| OXTR | -2112 |
| ABHD17B | -2101 |
| PRR5 | -2094 |
| FOXO4 | -2077 |
| RICTOR | -2076 |
| KRAS | -2044 |
| ARHGEF19 | -2038 |
| TP53 | -2020 |
| DLG2 | -2019 |
| DDX39B | -1996 |
| SPRY2 | -1990 |
| DGKQ | -1982 |
| DOCK8 | -1981 |
| DST | -1950 |
| AKT2 | -1946 |
| SPRY1 | -1918 |
| PSMB3 | -1915 |
| OTUD7B | -1911 |
| AP2A1 | -1902 |
| RGS10 | -1881 |
| MAPK13 | -1875 |
| XPO1 | -1864 |
| PIP5K1A | -1831 |
| APC | -1818 |
| WDR19 | -1802 |
| PKP4 | -1800 |
| SRGAP1 | -1796 |
| HNRNPA1 | -1795 |
| SRGAP2 | -1779 |
| SKI | -1777 |
| PRKAB2 | -1763 |
| DUSP16 | -1750 |
| NDE1 | -1744 |
| HECW1 | -1713 |
| PTCH1 | -1712 |
| CHN1 | -1698 |
| MMP3 | -1680 |
| NTSR1 | -1675 |
| ITGA3 | -1662 |
| ARAP2 | -1642 |
| ARAP1 | -1641 |
| NPHP4 | -1636 |
| TBL1X | -1621 |
| LGR5 | -1600 |
| DLAT | -1575 |
| PRKCH | -1569 |
| STAT6 | -1541 |
| NPB | -1537 |
| MUC13 | -1524 |
| STOM | -1523 |
| DNMBP | -1516 |
| ARPC5 | -1511 |
| RFNG | -1510 |
| PSMC3 | -1509 |
| HDAC4 | -1478 |
| WWOX | -1477 |
| EGR1 | -1475 |
| CCT7 | -1465 |
| PRKACB | -1429 |
| RND1 | -1410 |
| HDAC10 | -1408 |
| ADAP1 | -1403 |
| ARHGAP12 | -1400 |
| LFNG | -1376 |
| PLEKHG6 | -1364 |
| PIK3R2 | -1355 |
| CDK5 | -1352 |
| RANBP10 | -1342 |
| YES1 | -1340 |
| CHD3 | -1321 |
| ARHGAP18 | -1308 |
| LAMC1 | -1300 |
| PDE7A | -1290 |
| VRK3 | -1278 |
| TRA2B | -1257 |
| WDR6 | -1254 |
| CUL5 | -1229 |
| PDHA1 | -1224 |
| TULP3 | -1209 |
| ABI2 | -1197 |
| FGFR3 | -1195 |
| DOCK4 | -1171 |
| CAPZB | -1169 |
| RPS6KA2 | -1149 |
| PSMB4 | -1144 |
| CSNK1G2 | -1143 |
| RGS19 | -1130 |
| RCE1 | -1124 |
| MYO9A | -1107 |
| GATAD2B | -1092 |
| CCNK | -1089 |
| ARHGEF12 | -1086 |
| CDC42EP1 | -1064 |
| PLXNA1 | -1050 |
| PLXNB1 | -1046 |
| PRKAR1B | -1038 |
| HSP90AA1 | -1030 |
| MUC20 | -1019 |
| YWHAG | -1018 |
| GNB3 | -1008 |
| RALGAPA1 | -1001 |
| RALBP1 | -992 |
| NCKAP1L | -972 |
| MDM2 | -956 |
| SOS1 | -950 |
| MYO19 | -941 |
| LEMD3 | -919 |
| SH3KBP1 | -917 |
| ARHGEF18 | -909 |
| DVL2 | -905 |
| PSMA7 | -892 |
| SENP1 | -886 |
| YWHAZ | -885 |
| ATP6V1F | -868 |
| PTPN11 | -867 |
| PRKAR2A | -860 |
| IFT57 | -852 |
| NGFR | -847 |
| PRKCI | -826 |
| TPM4 | -822 |
| TGIF2 | -798 |
| KREMEN2 | -791 |
| WWC1 | -789 |
| PPARD | -788 |
| CDKN1B | -786 |
| WWP1 | -779 |
| LAMTOR1 | -774 |
| LTB4R | -754 |
| SHOC2 | -749 |
| PSMB5 | -742 |
| EPN1 | -737 |
| NLK | -733 |
| MAPK8 | -700 |
| VAMP3 | -698 |
| ITGA2B | -688 |
| C1QBP | -682 |
| PRKAB1 | -680 |
| LAMB3 | -673 |
| ADCY2 | -667 |
| CALM1 | -655 |
| DOCK6 | -639 |
| BAIAP2 | -637 |
| SPINT2 | -632 |
| PLEKHG5 | -630 |
| POLR2J | -603 |
| REST | -593 |
| ARHGAP28 | -582 |
| TRAF2 | -577 |
| RASGRP3 | -569 |
| NCSTN | -554 |
| PRKX | -553 |
| NDUFS3 | -551 |
| ITSN2 | -546 |
| SKP1 | -544 |
| ATP6V1E2 | -534 |
| JAG2 | -516 |
| BIRC2 | -499 |
| SOX7 | -497 |
| FGD2 | -487 |
| SMAD6 | -476 |
| CD19 | -472 |
| GABRG3 | -451 |
| GRIN1 | -442 |
| PSMD11 | -432 |
| ARHGAP40 | -424 |
| RDH13 | -415 |
| KALRN | -408 |
| ABCD3 | -405 |
| CENPO | -404 |
| LGR4 | -395 |
| SRRM1 | -354 |
| RUNX3 | -342 |
| HDAC2 | -338 |
| NUP160 | -329 |
| ADGRE5 | -313 |
| SOX6 | -307 |
| RASGEF1A | -290 |
| DUSP9 | -284 |
| ID2 | -282 |
| RASA4 | -277 |
| WWTR1 | -271 |
| B4GALT1 | -262 |
| CCL28 | -252 |
| NMB | -251 |
| ARHGAP10 | -233 |
| LAMC2 | -228 |
| SPOPL | -212 |
| ABR | -211 |
| STK3 | -207 |
| CNR2 | -204 |
| KCTD6 | -178 |
| PDE6A | -172 |
| BMPR1A | -166 |
| CDK5R1 | -157 |
| RPS27 | -152 |
| LAMTOR2 | -148 |
| CCND1 | -137 |
| PSMA6 | -126 |
| PAFAH1B1 | -118 |
| RBBP5 | -101 |
| SH3BP1 | -95 |
| LEPR | -88 |
| KDM4B | -59 |
| OFD1 | -45 |
| CTBP1 | -41 |
| TPM3 | -40 |
| PLPPR2 | -29 |
| COPS4 | -28 |
| GRK5 | -6 |
| RANBP2 | -4 |
| KSR1 | -1 |
| PRKAR1A | 4 |
| BAMBI | 6 |
| NOXO1 | 10 |
| ARHGEF1 | 21 |
| AKR1C3 | 24 |
| HDAC3 | 38 |
| ERCC6L | 39 |
| CSF2RA | 43 |
| RAC1 | 44 |
| RHOH | 49 |
| PDE6G | 70 |
| KITLG | 92 |
| CDC14A | 127 |
| YWHAE | 129 |
| HDAC7 | 130 |
| USP7 | 134 |
| ITSN1 | 159 |
| ARHGEF17 | 172 |
| RARG | 173 |
| TCIRG1 | 180 |
| NR1H2 | 193 |
| S1PR3 | 194 |
| NEDD4 | 196 |
| S1PR2 | 215 |
| RNF31 | 227 |
| MAPK11 | 251 |
| CAV2 | 254 |
| RALB | 270 |
| PPP2R5E | 283 |
| RAP1A | 309 |
| PORCN | 320 |
| GTF2A1 | 328 |
| STK10 | 333 |
| MOB1A | 340 |
| FGF5 | 342 |
| SUZ12 | 346 |
| IL1RL1 | 347 |
| KREMEN1 | 364 |
| PRKAG2 | 375 |
| PPP3CA | 381 |
| PTPRS | 397 |
| PDPK1 | 399 |
| RPTOR | 407 |
| SMPD2 | 417 |
| PSMB10 | 423 |
| RAPGEF4 | 438 |
| UCHL5 | 443 |
| E2F3 | 444 |
| NSMAF | 451 |
| GNAS | 459 |
| CREB1 | 474 |
| PLEKHG3 | 484 |
| SCFD1 | 485 |
| VPS29 | 494 |
| LAMB2 | 495 |
| RHOT2 | 515 |
| CRKL | 524 |
| MCF2L | 531 |
| YWHAQ | 542 |
| CCDC115 | 548 |
| GPSM1 | 559 |
| NRIP1 | 570 |
| STARD8 | 571 |
| NEDD8 | 580 |
| CCL22 | 584 |
| RAD21 | 601 |
| FRK | 602 |
| APH1A | 619 |
| PKN2 | 620 |
| F2 | 635 |
| ATP6V1G2 | 690 |
| GNB5 | 700 |
| LYL1 | 726 |
| CAB39L | 734 |
| MTMR1 | 739 |
| APOC1 | 746 |
| ATP6V0D2 | 747 |
| CENPL | 748 |
| NAB1 | 765 |
| ACVR2A | 775 |
| UBC | 779 |
| SMC1A | 784 |
| LAMA4 | 790 |
| TEX2 | 793 |
| DGKH | 802 |
| GNAQ | 803 |
| PTPRA | 815 |
| RASA2 | 817 |
| RNF146 | 825 |
| PBX1 | 827 |
| PHC3 | 843 |
| HSPE1 | 844 |
| MATK | 851 |
| SGK1 | 865 |
| SMPD3 | 874 |
| RXRB | 878 |
| ARHGAP4 | 930 |
| ACVR2B | 931 |
| ELMO2 | 942 |
| ABHD6 | 957 |
| TCF7L2 | 959 |
| PLEKHG1 | 966 |
| ARTN | 973 |
| ARHGEF4 | 980 |
| CTTN | 982 |
| GPR39 | 994 |
| HDAC11 | 1004 |
| MYH11 | 1015 |
| PAK1 | 1031 |
| PIP5K1B | 1047 |
| PML | 1051 |
| PSMB1 | 1054 |
| ADGRE2 | 1057 |
| LTB4R2 | 1059 |
| E2F5 | 1069 |
| PPP1R12A | 1114 |
| SOX13 | 1115 |
| TRAK2 | 1119 |
| PIK3R4 | 1132 |
| TBXA2R | 1137 |
| SH2B2 | 1149 |
| GRK6 | 1151 |
| FMNL3 | 1155 |
| GABRB3 | 1163 |
| BUB3 | 1165 |
| LAMC3 | 1169 |
| LRRC1 | 1170 |
| GPR161 | 1180 |
| RNF43 | 1197 |
| GRK2 | 1205 |
| BRAP | 1211 |
| FNBP1L | 1226 |
| OPRD1 | 1233 |
| FZD3 | 1245 |
| EPS15 | 1254 |
| POU2F1 | 1266 |
| ARHGDIG | 1275 |
| ARFGAP2 | 1283 |
| LAMA1 | 1285 |
| RBFOX2 | 1286 |
| RAB6A | 1296 |
| MEN1 | 1298 |
| RHOD | 1302 |
| ARHGAP22 | 1306 |
| CGN | 1314 |
| FLOT1 | 1317 |
| GRIN2B | 1330 |
| KHDRBS1 | 1341 |
| MOSPD2 | 1344 |
| GPR83 | 1350 |
| NRP1 | 1353 |
| NUP133 | 1362 |
| CENPP | 1371 |
| BTRC | 1386 |
| TBL1XR1 | 1404 |
| ZFYVE9 | 1407 |
| RAC3 | 1423 |
| ACTR2 | 1435 |
| SLITRK5 | 1437 |
| USP4 | 1449 |
| CXCR2 | 1464 |
| DISP2 | 1498 |
| NCK1 | 1525 |
| SMAD5 | 1543 |
| CLASP1 | 1561 |
| LIMK1 | 1565 |
| GAB1 | 1575 |
| KAT5 | 1580 |
| EBAG9 | 1586 |
| IRAK4 | 1591 |
| TRAF6 | 1597 |
| SPARC | 1607 |
| RDH16 | 1613 |
| PYGO2 | 1616 |
| GOPC | 1629 |
| F3 | 1642 |
| NF1 | 1648 |
| MIB1 | 1650 |
| RGS2 | 1680 |
| DGKG | 1694 |
| CDKN2B | 1710 |
| CAMK2D | 1711 |
| PRKACA | 1736 |
| DOCK9 | 1751 |
| HTR1D | 1778 |
| PDHB | 1808 |
| MTA1 | 1810 |
| HNRNPC | 1814 |
| TNRC6A | 1824 |
| LAMTOR4 | 1834 |
| NSFL1C | 1848 |
| MLST8 | 1875 |
| PSMB2 | 1876 |
| FASN | 1885 |
| FADD | 1889 |
| MYC | 1892 |
| CCR4 | 1897 |
| RASGRF1 | 1900 |
| CCR10 | 1905 |
| BCL2 | 1925 |
| VWF | 1933 |
| GNB4 | 1936 |
| FYN | 1937 |
| CYFIP1 | 1939 |
| RHPN2 | 1950 |
| GAS8 | 1964 |
| IL6ST | 1965 |
| LRRC41 | 1992 |
| POLR2G | 2003 |
| SGO1 | 2010 |
| RASAL2 | 2019 |
| PICALM | 2021 |
| ABL1 | 2023 |
| AP2B1 | 2029 |
| TGIF1 | 2034 |
| CASR | 2065 |
| EPO | 2073 |
| YWHAB | 2082 |
| COL6A3 | 2085 |
| FAM13A | 2086 |
| FGF23 | 2097 |
| SYDE2 | 2107 |
| FRS3 | 2112 |
| BMPR2 | 2124 |
| CAMK2G | 2145 |
| WDR35 | 2156 |
| FLT4 | 2167 |
| YAP1 | 2171 |
| CYBA | 2202 |
| ID3 | 2220 |
| SSTR5 | 2225 |
| ITPR2 | 2257 |
| AGTR1 | 2260 |
| FZD8 | 2263 |
| CENPN | 2264 |
| MAPK14 | 2269 |
| FOXO3 | 2282 |
| FAS | 2303 |
| NRAS | 2310 |
| JUP | 2314 |
| ALS2 | 2318 |
| HCAR1 | 2353 |
| FAM169A | 2362 |
| EED | 2369 |
| IFT122 | 2370 |
| SPTAN1 | 2385 |
| PDK1 | 2405 |
| WNT6 | 2412 |
| POLR2D | 2418 |
| PRKCA | 2439 |
| PDE4C | 2441 |
| RNF111 | 2443 |
| RNF2 | 2454 |
| EVL | 2467 |
| TAS1R1 | 2471 |
| EIF4E | 2473 |
| SYNGAP1 | 2484 |
| ALDH8A1 | 2489 |
| MPP7 | 2491 |
| DIAPH2 | 2492 |
| CYSLTR1 | 2493 |
| DYNLL1 | 2509 |
| PLCG1 | 2511 |
| THBS2 | 2512 |
| PHIP | 2538 |
| SMC3 | 2546 |
| PXN | 2548 |
| GFAP | 2552 |
| MYH10 | 2558 |
| RASA1 | 2559 |
| TAB3 | 2566 |
| SUFU | 2576 |
| RRAGA | 2609 |
| TFF1 | 2618 |
| WASF3 | 2619 |
| CDK9 | 2631 |
| PIP4K2B | 2639 |
| SMO | 2649 |
| MYO6 | 2665 |
| CDON | 2669 |
| STMN1 | 2680 |
| PPP5C | 2684 |
| F2RL3 | 2685 |
| TRAF1 | 2688 |
| LPAR2 | 2695 |
| MYL9 | 2704 |
| POLR2A | 2705 |
| FGD1 | 2720 |
| NBEA | 2723 |
| SMAD4 | 2742 |
| PPP2R5C | 2743 |
| CCNE1 | 2754 |
| PAG1 | 2774 |
| KISS1R | 2780 |
| USP21 | 2804 |
| NUP43 | 2808 |
| CTSD | 2812 |
| GALR1 | 2816 |
| VAV2 | 2817 |
| ARHGAP1 | 2833 |
| CETP | 2836 |
| GABRG2 | 2849 |
| IFT52 | 2860 |
| RGS9 | 2861 |
| HCAR2 | 2882 |
| CBX6 | 2911 |
| UTS2B | 2923 |
| SPPL2B | 2936 |
| ABCG8 | 2955 |
| AAAS | 2965 |
| DRAP1 | 2970 |
| PARP1 | 2974 |
| TMOD3 | 2983 |
| ICMT | 2988 |
| MOB1B | 3012 |
| ARPC1A | 3022 |
| DTX4 | 3048 |
| PIN1 | 3074 |
| STAM2 | 3080 |
| RPS6KA5 | 3086 |
| SLC4A7 | 3094 |
| KLC3 | 3105 |
| HNRNPH1 | 3111 |
| SMAD7 | 3117 |
| SHARPIN | 3128 |
| LIN7B | 3131 |
| TACC3 | 3154 |
| CASP8 | 3157 |
| RAB4B | 3174 |
| DHRS3 | 3195 |
| SHKBP1 | 3221 |
| COL6A2 | 3222 |
| PLEKHG4 | 3233 |
| CSNK1E | 3247 |
| HCAR3 | 3253 |
| CTNNB1 | 3272 |
| KIF3A | 3299 |
| PTK6 | 3304 |
| STRADB | 3307 |
| PEA15 | 3314 |
| ESR2 | 3316 |
| DLK1 | 3351 |
| PKN3 | 3362 |
| STUB1 | 3373 |
| LYPLA1 | 3378 |
| NLN | 3407 |
| TCF7L1 | 3414 |
| BUB1 | 3416 |
| DBT | 3444 |
| WDR11 | 3445 |
| PCSK5 | 3449 |
| RANGAP1 | 3458 |
| STK4 | 3459 |
| EREG | 3467 |
| BIRC3 | 3477 |
| EPS15L1 | 3478 |
| LBR | 3485 |
| XCL1 | 3488 |
| C5AR2 | 3489 |
| IRS1 | 3502 |
| FLRT1 | 3504 |
| NSL1 | 3516 |
| CARM1 | 3517 |
| UBE2D1 | 3523 |
| CDC14B | 3537 |
| DOCK1 | 3540 |
| VAPB | 3551 |
| GIPR | 3556 |
| RAP1B | 3577 |
| GNRHR2 | 3579 |
| OBSCN | 3598 |
| IFT172 | 3605 |
| PTPN1 | 3622 |
| CXCL8 | 3625 |
| WNT11 | 3642 |
| TRAK1 | 3646 |
| CNKSR1 | 3649 |
| FARP2 | 3688 |
| NR4A1 | 3691 |
| PHC2 | 3713 |
| VANGL2 | 3723 |
| EFHD2 | 3725 |
| PTGES3 | 3734 |
| ARHGAP11A | 3756 |
| MYLK | 3757 |
| PAQR3 | 3763 |
| MAP3K7 | 3767 |
| PLIN1 | 3775 |
| NEURL1B | 3778 |
| LAMB1 | 3783 |
| ARPC3 | 3797 |
| DOCK7 | 3822 |
| CTNNBIP1 | 3826 |
| CAMKK2 | 3831 |
| HDAC8 | 3835 |
| PRKAG1 | 3836 |
| F2R | 3850 |
| CPT1B | 3852 |
| NRTN | 3870 |
| SPTBN2 | 3883 |
| TRADD | 3885 |
| KLC4 | 3897 |
| SRC | 3962 |
| PYGO1 | 3963 |
| TBP | 3968 |
| GPSM2 | 3970 |
| FLRT2 | 3988 |
| EPOR | 3992 |
| GOLGA8R | 4017 |
| BAG4 | 4019 |
| FABP5 | 4021 |
| ARHGEF3 | 4045 |
| PLD2 | 4048 |
| DEF6 | 4058 |
| PCP2 | 4061 |
| RING1 | 4067 |
| HHAT | 4068 |
| DOK1 | 4072 |
| CCL16 | 4092 |
| RHOT1 | 4106 |
| CDK2 | 4114 |
| CCNT2 | 4117 |
| GNG5 | 4123 |
| GPNMB | 4151 |
| POFUT1 | 4155 |
| NDUFA5 | 4165 |
| DLD | 4167 |
| ZFYVE16 | 4169 |
| NUP85 | 4178 |
| CAMK4 | 4196 |
| CENPF | 4197 |
| GGA3 | 4199 |
| CASP2 | 4204 |
| KDM1A | 4224 |
| ERBB3 | 4249 |
| STAT3 | 4253 |
| ADCY9 | 4287 |
| NPFFR1 | 4289 |
| NOTCH3 | 4292 |
| PSMD12 | 4303 |
| AGO1 | 4307 |
| ULK3 | 4342 |
| MAD1L1 | 4350 |
| CENPU | 4358 |
| TNFAIP3 | 4359 |
| WDR91 | 4363 |
| CHEK1 | 4365 |
| GNAL | 4390 |
| GFRA3 | 4393 |
| ACVR1B | 4400 |
| GIT2 | 4402 |
| VCL | 4407 |
| DKK1 | 4410 |
| ZDHHC21 | 4413 |
| CSNK2B | 4415 |
| TRIP10 | 4417 |
| GNG7 | 4426 |
| IFT140 | 4429 |
| FER | 4431 |
| PTPRU | 4441 |
| THBS3 | 4450 |
| TIAM1 | 4452 |
| ATP2A1 | 4477 |
| TTC21B | 4480 |
| ID1 | 4484 |
| PTAFR | 4486 |
| DOCK5 | 4491 |
| IL17RD | 4497 |
| ARHGAP29 | 4530 |
| CENPA | 4546 |
| ATP6V1B1 | 4549 |
| GTF2F2 | 4556 |
| TERT | 4560 |
| JUND | 4563 |
| CAMK2A | 4566 |
| PSMD4 | 4567 |
| ELF3 | 4575 |
| RHOU | 4579 |
| FZD1 | 4591 |
| POLR2I | 4594 |
| PDK4 | 4595 |
| DRD5 | 4609 |
| KLC1 | 4611 |
| PPP2R1B | 4614 |
| MDK | 4615 |
| RALGDS | 4617 |
| KCTD3 | 4624 |
| ARHGAP27 | 4643 |
| ARHGEF39 | 4647 |
| RBL1 | 4660 |
| STAP2 | 4664 |
| NR1H3 | 4678 |
| ARHGAP33 | 4686 |
| TPH1 | 4694 |
| CENPT | 4715 |
| PDE11A | 4728 |
| ASH2L | 4729 |
| POTEE | 4752 |
| BAX | 4757 |
| PLPPR1 | 4765 |
| NCOA2 | 4780 |
| RBPJ | 4794 |
| PLAT | 4797 |
| TNFRSF1A | 4807 |
| ADCY1 | 4808 |
| SKA1 | 4823 |
| KANK1 | 4837 |
| FZD5 | 4841 |
| TFDP2 | 4856 |
| EIF4EBP1 | 4858 |
| AHCYL1 | 4874 |
| DUSP8 | 4879 |
| SCAI | 4892 |
| ARHGEF26 | 4909 |
| PSMD10 | 4933 |
| PSMD7 | 4942 |
| SMAD1 | 4977 |
| ANLN | 4979 |
| TLE2 | 5001 |
| AMER1 | 5007 |
| ARHGAP8 | 5008 |
| DIAPH3 | 5020 |
| TAS2R4 | 5037 |
| PLK1 | 5045 |
| SOCS1 | 5053 |
| TYK2 | 5066 |
| KAT2A | 5077 |
| ARHGEF9 | 5100 |
| DLG4 | 5108 |
| STAM | 5109 |
| PSMD5 | 5116 |
| MRAS | 5118 |
| ADORA2B | 5127 |
| RBBP7 | 5134 |
| MST1R | 5156 |
| DLG3 | 5168 |
| BIRC5 | 5174 |
| PRKAA1 | 5206 |
| FRAT1 | 5212 |
| ACKR2 | 5219 |
| KIF14 | 5224 |
| KIF18A | 5234 |
| UACA | 5249 |
| CENPM | 5262 |
| CCDC88A | 5267 |
| DGKK | 5277 |
| SGO2 | 5279 |
| APOC2 | 5283 |
| STAT5A | 5288 |
| GPR176 | 5289 |
| INCENP | 5290 |
| RDH5 | 5315 |
| RUVBL1 | 5317 |
| PCSK6 | 5326 |
| ADORA2A | 5330 |
| FKBP5 | 5342 |
| CLIP3 | 5347 |
| H2AFX | 5356 |
| IL1RAP | 5361 |
| CDC42SE2 | 5380 |
| ARHGEF10L | 5384 |
| CEP97 | 5393 |
| TRIB1 | 5404 |
| FOXO1 | 5418 |
| IL32 | 5419 |
| TNFSF10 | 5424 |
| IFT88 | 5432 |
| GTF2A2 | 5445 |
| OXER1 | 5459 |
| SRY | 5473 |
| NCKIPSD | 5477 |
| FZD7 | 5487 |
| PSMB9 | 5491 |
| MYH14 | 5492 |
| DZIP1 | 5496 |
| NOXA1 | 5500 |
| FES | 5506 |
| ERBB2 | 5534 |
| CENPE | 5538 |
| ADRA1D | 5547 |
| CNOT6L | 5623 |
| EVC | 5630 |
| CDC20 | 5650 |
| CENPC | 5660 |
| DLGAP5 | 5662 |
| ATP6V0E2 | 5683 |
| ADD3 | 5685 |
| INTU | 5699 |
| DGKA | 5708 |
| ARL2 | 5716 |
| RACGAP1 | 5789 |
| MAGED1 | 5797 |
| UCN | 5800 |
| SYDE1 | 5815 |
| GMIP | 5817 |
| SH2D2A | 5820 |
| RNF20 | 5837 |
| TF | 5850 |
| FARP1 | 5879 |
| SERPINE1 | 5901 |
| CENPQ | 5907 |
| FOXA1 | 5915 |
| ST3GAL3 | 5918 |
| PARD6A | 5924 |
| MYD88 | 5939 |
| HDAC6 | 5953 |
| ARL13B | 5956 |
| POLR2K | 5962 |
| CENPI | 5963 |
| CBY1 | 5965 |
| PSMD14 | 5974 |
| RHOBTB1 | 5975 |
| KIF2C | 5981 |
| ZWINT | 5984 |
| NISCH | 5985 |
| THBS1 | 5988 |
| TNFAIP1 | 5996 |
| FLT3LG | 6000 |
| CIT | 6027 |
| DYNLL2 | 6044 |
| USP13 | 6054 |
| MTR | 6057 |
| RHOB | 6064 |
| NUP107 | 6076 |
| ANKFY1 | 6079 |
| THEM4 | 6080 |
| ARHGAP11B | 6085 |
| ARHGAP44 | 6102 |
| DEPDC1B | 6112 |
| SMAD9 | 6128 |
| GNG4 | 6164 |
| APH1B | 6168 |
| RNF41 | 6188 |
| ABHD17C | 6192 |
| EFCAB7 | 6202 |
| CCP110 | 6203 |
| KIF7 | 6216 |
| CYFIP2 | 6224 |
| TJP2 | 6225 |
| HINT2 | 6227 |
| NOTCH2 | 6231 |
| ADH1A | 6237 |
| CENPH | 6241 |
| ZWILCH | 6246 |
| PTCH2 | 6287 |
| RAMP2 | 6288 |
| TIA1 | 6310 |
| FZD6 | 6312 |
| ADCY7 | 6316 |
| OPHN1 | 6348 |
| RDH11 | 6369 |
| FGD4 | 6382 |
| LIMK2 | 6394 |
| ITGB3BP | 6398 |
| MOV10 | 6408 |
| MTA3 | 6411 |
| MKS1 | 6422 |
| UBXN11 | 6442 |
| RGL3 | 6456 |
| DHRS4 | 6459 |
| ARHGEF40 | 6470 |
| DNM1 | 6505 |
| SKA2 | 6507 |
| PCK1 | 6525 |
| OPRL1 | 6531 |
| FZD4 | 6534 |
| PRC1 | 6550 |
| SSTR3 | 6553 |
| PTPN6 | 6557 |
| RGS5 | 6561 |
| TAS2R5 | 6569 |
| STAT5B | 6572 |
| AGO4 | 6581 |
| RHPN1 | 6595 |
| ABCG5 | 6607 |
| DNAL4 | 6609 |
| PDE6D | 6611 |
| CKAP5 | 6626 |
| LAMA5 | 6638 |
| MAPK3 | 6640 |
| CDCA8 | 6649 |
| SCMH1 | 6656 |
| STRADA | 6661 |
| KNTC1 | 6674 |
| OPN3 | 6679 |
| TAB1 | 6687 |
| COL4A5 | 6694 |
| FGG | 6697 |
| HGFAC | 6708 |
| SPDL1 | 6715 |
| C5AR1 | 6719 |
| FGFBP3 | 6730 |
| ARHGAP19 | 6733 |
| MFNG | 6743 |
| GREB1 | 6757 |
| EDN1 | 6766 |
| KBTBD7 | 6772 |
| SRGAP3 | 6775 |
| GNG10 | 6779 |
| PTGDR2 | 6780 |
| NOTUM | 6788 |
| PTK2B | 6809 |
| FGFR2 | 6811 |
| ZNF217 | 6814 |
| HPN | 6820 |
| NCBP2 | 6823 |
| CDC25C | 6825 |
| PDK2 | 6826 |
| RPGRIP1L | 6834 |
| OCRL | 6835 |
| KLHL12 | 6844 |
| MAML2 | 6847 |
| PTPN18 | 6851 |
| CPD | 6859 |
| PFN2 | 6877 |
| AURKB | 6883 |
| DSN1 | 6916 |
| PDGFB | 6920 |
| LPAR6 | 6924 |
| IQGAP3 | 6928 |
| SALL4 | 6934 |
| CBX2 | 6958 |
| EEF2K | 6964 |
| TMPO | 6967 |
| GPAM | 6968 |
| SCD | 6981 |
| BUB1B | 6992 |
| NUF2 | 7008 |
| ANKRD26 | 7017 |
| SPC24 | 7021 |
| CENPK | 7030 |
| FGD3 | 7036 |
| F11R | 7054 |
| SEMA4F | 7059 |
| NGEF | 7064 |
| MAD2L1 | 7070 |
| KNL1 | 7073 |
| CPT1A | 7075 |
| MC1R | 7078 |
| AGT | 7091 |
| TUBA1B | 7094 |
| E2F1 | 7096 |
| NUP37 | 7100 |
| LMNB1 | 7101 |
| SOX9 | 7103 |
| CTNND1 | 7129 |
| FLOT2 | 7147 |
| COL9A3 | 7151 |
| NDC80 | 7161 |
| THBS4 | 7170 |
| FLRT3 | 7184 |
| C5 | 7218 |
| FGB | 7226 |
| BEX3 | 7227 |
| CDK1 | 7230 |
| NEDD4L | 7233 |
| HES1 | 7265 |
| RHOBTB2 | 7276 |
| PLD1 | 7290 |
| CDH1 | 7296 |
| COL6A1 | 7322 |
| TFF3 | 7324 |
| JAK3 | 7326 |
| ADH4 | 7331 |
| FGA | 7336 |
| COL9A2 | 7348 |
| C3 | 7357 |
| ACTA2 | 7362 |
| SOCS3 | 7374 |
| IGF2 | 7375 |
| PLG | 7380 |
| KNG1 | 7382 |
Cholesterol biosynthesis
| 162 | |
|---|---|
| set | Cholesterol biosynthesis |
| setSize | 24 |
| pANOVA | 8.63e-13 |
| s.dist | 0.843 |
| p.adjustANOVA | 8.49e-11 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MSMO1 | 7385 |
| HMGCS1 | 7372 |
| SQLE | 7370 |
| IDI1 | 7367 |
| HMGCR | 7355 |
| MVK | 7340 |
| DHCR7 | 7333 |
| MVD | 7302 |
| FDFT1 | 7289 |
| LSS | 7283 |
| ACAT2 | 6959 |
| ARV1 | 6888 |
| FDPS | 6789 |
| CYP51A1 | 6741 |
| TM7SF2 | 6684 |
| NSDHL | 6245 |
| DHCR24 | 5816 |
| GGPS1 | 5520 |
| SC5D | 5323 |
| EBP | 5151 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MSMO1 | 7385 |
| HMGCS1 | 7372 |
| SQLE | 7370 |
| IDI1 | 7367 |
| HMGCR | 7355 |
| MVK | 7340 |
| DHCR7 | 7333 |
| MVD | 7302 |
| FDFT1 | 7289 |
| LSS | 7283 |
| ACAT2 | 6959 |
| ARV1 | 6888 |
| FDPS | 6789 |
| CYP51A1 | 6741 |
| TM7SF2 | 6684 |
| NSDHL | 6245 |
| DHCR24 | 5816 |
| GGPS1 | 5520 |
| SC5D | 5323 |
| EBP | 5151 |
| PLPP6 | 4705 |
| LBR | 3485 |
| PMVK | 3336 |
| HSD17B7 | 2596 |
Translation
| 1283 | |
|---|---|
| set | Translation |
| setSize | 270 |
| pANOVA | 9.51e-13 |
| s.dist | -0.253 |
| p.adjustANOVA | 8.73e-11 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SEC61A1 | -7030 |
| RPN1 | -7013 |
| SSR4 | -7004 |
| TRAM1 | -6997 |
| EIF4A1 | -6995 |
| SEC11C | -6991 |
| RPL36AL | -6981 |
| EIF3A | -6965 |
| SEC61B | -6958 |
| ETF1 | -6952 |
| SSR3 | -6928 |
| SSR1 | -6907 |
| SRPRB | -6893 |
| GSPT1 | -6825 |
| SPCS3 | -6781 |
| SSR2 | -6759 |
| DDOST | -6429 |
| SRP68 | -6420 |
| MTRF1L | -6400 |
| SRP19 | -6363 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SEC61A1 | -7030 |
| RPN1 | -7013 |
| SSR4 | -7004 |
| TRAM1 | -6997 |
| EIF4A1 | -6995 |
| SEC11C | -6991 |
| RPL36AL | -6981 |
| EIF3A | -6965 |
| SEC61B | -6958 |
| ETF1 | -6952 |
| SSR3 | -6928 |
| SSR1 | -6907 |
| SRPRB | -6893 |
| GSPT1 | -6825 |
| SPCS3 | -6781 |
| SSR2 | -6759 |
| DDOST | -6429 |
| SRP68 | -6420 |
| MTRF1L | -6400 |
| SRP19 | -6363 |
| RPN2 | -6193 |
| EIF5 | -6065 |
| SRP14 | -5938 |
| SPCS2 | -5930 |
| EIF4G1 | -5901 |
| EIF4B | -5898 |
| MRPS6 | -5687 |
| SRP72 | -5526 |
| MRPS15 | -5376 |
| EIF3I | -5279 |
| RPL19 | -5254 |
| MRPL38 | -5234 |
| EIF2S1 | -5190 |
| MRPS2 | -5145 |
| RPS7 | -5138 |
| EIF3B | -5127 |
| EEF1D | -5115 |
| AURKAIP1 | -5100 |
| MRPS12 | -5083 |
| UBA52 | -5068 |
| EIF4H | -5055 |
| MRPL3 | -5054 |
| EEF2 | -5049 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| MRPL47 | -4976 |
| MRPL14 | -4864 |
| EIF2B5 | -4838 |
| EEF1B2 | -4836 |
| EIF2B2 | -4811 |
| SRPRA | -4802 |
| MRPL23 | -4800 |
| RPS5 | -4778 |
| EIF3G | -4724 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| MRPL34 | -4611 |
| MRPL41 | -4594 |
| MRPL35 | -4563 |
| EIF3J | -4539 |
| MRPL32 | -4532 |
| MRPS18C | -4493 |
| MRPL51 | -4467 |
| EIF2S2 | -4458 |
| MRPL46 | -4455 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| EIF3M | -4358 |
| MRPS24 | -4327 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| MRPL33 | -4189 |
| RPL35A | -4159 |
| EEF1A1 | -4138 |
| MRPL44 | -4094 |
| RPL30 | -4081 |
| SEC61G | -4052 |
| RPS9 | -4028 |
| EEF1E1 | -4013 |
| RPL18 | -3961 |
| GADD45GIP1 | -3917 |
| MRPS22 | -3909 |
| RPL26L1 | -3873 |
| TRMT112 | -3869 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| EIF3D | -3740 |
| EIF2S3 | -3669 |
| EEF1G | -3612 |
| RPL28 | -3546 |
| PABPC1 | -3543 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| TUFM | -3458 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| MRPS18B | -3346 |
| MRPS36 | -3292 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| SEC11A | -3046 |
| RPS15A | -3019 |
| MRPL54 | -3013 |
| MRPL37 | -2997 |
| RPL7 | -2984 |
| FARSA | -2976 |
| RPL34 | -2974 |
| MRPL36 | -2957 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| GFM1 | -2827 |
| RPS27A | -2773 |
| MRRF | -2721 |
| MRPL57 | -2716 |
| MRPS34 | -2704 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| MRPS23 | -2664 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| MRPL48 | -2613 |
| RPS13 | -2581 |
| GFM2 | -2567 |
| RPL4 | -2563 |
| MRPS28 | -2470 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| MRPL39 | -2415 |
| EIF3L | -2407 |
| MRPS11 | -2271 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| EIF3K | -2206 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| MRPL22 | -2025 |
| SRP54 | -1969 |
| MRPL4 | -1923 |
| RPL23 | -1913 |
| VARS2 | -1827 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| IARS2 | -1767 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| EEF1A1P5 | -1745 |
| MRPS30 | -1657 |
| PPA1 | -1553 |
| MRPS35 | -1461 |
| SEC61A2 | -1397 |
| MRPL53 | -1391 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| RPL17 | -1119 |
| TSFM | -1098 |
| RPS8 | -1071 |
| MRPS9 | -1007 |
| RPL12 | -983 |
| RPS25 | -937 |
| EIF3F | -893 |
| MRPL18 | -882 |
| MRPL9 | -726 |
| RPL13 | -706 |
| YARS2 | -645 |
| MRPS18A | -532 |
| SARS2 | -521 |
| RPL5 | -495 |
| MRPS10 | -474 |
| MRPL40 | -473 |
| MRPL50 | -402 |
| EIF3C | -374 |
| EIF1AX | -274 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| MTIF3 | -173 |
| RPS27 | -152 |
| EIF2B1 | -143 |
| MRPL19 | 96 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPS26 | 419 |
| EIF2B4 | 437 |
| MRPL13 | 482 |
| EEF1A2 | 553 |
| MTIF2 | 664 |
| MRPL20 | 773 |
| MRPS14 | 785 |
| MRPS5 | 787 |
| MRPS17 | 895 |
| EIF3H | 899 |
| DAP3 | 972 |
| MRPL28 | 1039 |
| CHCHD1 | 1058 |
| AIMP2 | 1067 |
| EARS2 | 1253 |
| FARS2 | 1328 |
| MRPL58 | 1346 |
| RPL21 | 1385 |
| MRPL15 | 1406 |
| PTCD3 | 1514 |
| MRPL52 | 1657 |
| MRPS7 | 1777 |
| AIMP1 | 1790 |
| MARS2 | 1957 |
| CARS2 | 2078 |
| NARS2 | 2113 |
| RPL22 | 2142 |
| ERAL1 | 2351 |
| OXA1L | 2372 |
| MRPS27 | 2381 |
| PPA2 | 2403 |
| SPCS1 | 2416 |
| DARS2 | 2466 |
| EIF4E | 2473 |
| MRPL21 | 2518 |
| TARS2 | 2575 |
| MRPL27 | 2747 |
| RPL36A | 2875 |
| MTFMT | 3156 |
| EIF3E | 3244 |
| MRPS26 | 3245 |
| FARSB | 3269 |
| EIF5B | 3318 |
| MRPL10 | 3731 |
| MRPL49 | 4062 |
| MRPL11 | 4075 |
| WARS2 | 4080 |
| MRPL12 | 4261 |
| APEH | 4698 |
| MRPS33 | 4704 |
| MRPL43 | 4791 |
| EIF4EBP1 | 4858 |
| MRPS21 | 4888 |
| RARS2 | 5085 |
| EIF2B3 | 5203 |
| MRPL42 | 5341 |
| EIF4A2 | 5593 |
| SRP9 | 5604 |
| HARS2 | 5687 |
| AARS2 | 5743 |
| MRPL55 | 5826 |
| MRPL1 | 5865 |
| MRPL16 | 5878 |
| MRPS16 | 5883 |
| MRPL17 | 5943 |
| MRPL30 | 5960 |
| MRPL2 | 6122 |
| LARS2 | 6133 |
| MRPS31 | 6190 |
| MRPL24 | 6982 |
| MRPS25 | 7089 |
| PARS2 | 7123 |
| N6AMT1 | 7144 |
Cap-dependent Translation Initiation
| 128 | |
|---|---|
| set | Cap-dependent Translation Initiation |
| setSize | 116 |
| pANOVA | 1.61e-12 |
| s.dist | -0.38 |
| p.adjustANOVA | 1.3e-10 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| EIF4A1 | -6995 |
| RPL36AL | -6981 |
| EIF3A | -6965 |
| EIF5 | -6065 |
| EIF4G1 | -5901 |
| EIF4B | -5898 |
| EIF3I | -5279 |
| RPL19 | -5254 |
| EIF2S1 | -5190 |
| RPS7 | -5138 |
| EIF3B | -5127 |
| UBA52 | -5068 |
| EIF4H | -5055 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| EIF2B5 | -4838 |
| EIF2B2 | -4811 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| EIF4A1 | -6995 |
| RPL36AL | -6981 |
| EIF3A | -6965 |
| EIF5 | -6065 |
| EIF4G1 | -5901 |
| EIF4B | -5898 |
| EIF3I | -5279 |
| RPL19 | -5254 |
| EIF2S1 | -5190 |
| RPS7 | -5138 |
| EIF3B | -5127 |
| UBA52 | -5068 |
| EIF4H | -5055 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| EIF2B5 | -4838 |
| EIF2B2 | -4811 |
| RPS5 | -4778 |
| EIF3G | -4724 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| EIF3J | -4539 |
| EIF2S2 | -4458 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| EIF3M | -4358 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| RPL30 | -4081 |
| RPS9 | -4028 |
| RPL18 | -3961 |
| RPL26L1 | -3873 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| EIF3D | -3740 |
| EIF2S3 | -3669 |
| RPL28 | -3546 |
| PABPC1 | -3543 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| RPS15A | -3019 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| RPS27A | -2773 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| EIF3L | -2407 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| EIF3K | -2206 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| RPL23 | -1913 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| RPS25 | -937 |
| EIF3F | -893 |
| RPL13 | -706 |
| RPL5 | -495 |
| EIF3C | -374 |
| EIF1AX | -274 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| EIF2B1 | -143 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPS26 | 419 |
| EIF2B4 | 437 |
| EIF3H | 899 |
| RPL21 | 1385 |
| RPL22 | 2142 |
| EIF4E | 2473 |
| RPL36A | 2875 |
| EIF3E | 3244 |
| EIF5B | 3318 |
| EIF4EBP1 | 4858 |
| EIF2B3 | 5203 |
| EIF4A2 | 5593 |
Eukaryotic Translation Initiation
| 337 | |
|---|---|
| set | Eukaryotic Translation Initiation |
| setSize | 116 |
| pANOVA | 1.61e-12 |
| s.dist | -0.38 |
| p.adjustANOVA | 1.3e-10 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| EIF4A1 | -6995 |
| RPL36AL | -6981 |
| EIF3A | -6965 |
| EIF5 | -6065 |
| EIF4G1 | -5901 |
| EIF4B | -5898 |
| EIF3I | -5279 |
| RPL19 | -5254 |
| EIF2S1 | -5190 |
| RPS7 | -5138 |
| EIF3B | -5127 |
| UBA52 | -5068 |
| EIF4H | -5055 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| EIF2B5 | -4838 |
| EIF2B2 | -4811 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| EIF4A1 | -6995 |
| RPL36AL | -6981 |
| EIF3A | -6965 |
| EIF5 | -6065 |
| EIF4G1 | -5901 |
| EIF4B | -5898 |
| EIF3I | -5279 |
| RPL19 | -5254 |
| EIF2S1 | -5190 |
| RPS7 | -5138 |
| EIF3B | -5127 |
| UBA52 | -5068 |
| EIF4H | -5055 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| EIF2B5 | -4838 |
| EIF2B2 | -4811 |
| RPS5 | -4778 |
| EIF3G | -4724 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| EIF3J | -4539 |
| EIF2S2 | -4458 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| EIF3M | -4358 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| RPL30 | -4081 |
| RPS9 | -4028 |
| RPL18 | -3961 |
| RPL26L1 | -3873 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| EIF3D | -3740 |
| EIF2S3 | -3669 |
| RPL28 | -3546 |
| PABPC1 | -3543 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| RPS15A | -3019 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| RPS27A | -2773 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| EIF3L | -2407 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| EIF3K | -2206 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| RPL23 | -1913 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| RPS25 | -937 |
| EIF3F | -893 |
| RPL13 | -706 |
| RPL5 | -495 |
| EIF3C | -374 |
| EIF1AX | -274 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| EIF2B1 | -143 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPS26 | 419 |
| EIF2B4 | 437 |
| EIF3H | 899 |
| RPL21 | 1385 |
| RPL22 | 2142 |
| EIF4E | 2473 |
| RPL36A | 2875 |
| EIF3E | 3244 |
| EIF5B | 3318 |
| EIF4EBP1 | 4858 |
| EIF2B3 | 5203 |
| EIF4A2 | 5593 |
Regulation of expression of SLITs and ROBOs
| 978 | |
|---|---|
| set | Regulation of expression of SLITs and ROBOs |
| setSize | 157 |
| pANOVA | 2.15e-12 |
| s.dist | -0.325 |
| p.adjustANOVA | 1.65e-10 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| ETF1 | -6952 |
| RNPS1 | -6938 |
| GSPT1 | -6825 |
| PSMF1 | -6663 |
| PSME4 | -6450 |
| PSMD2 | -6435 |
| UPF3A | -6189 |
| CASC3 | -5986 |
| PSMD6 | -5951 |
| EIF4G1 | -5901 |
| PSMA2 | -5801 |
| PSMA1 | -5730 |
| ROBO1 | -5577 |
| PSMC1 | -5564 |
| PSMD3 | -5535 |
| PSME2 | -5481 |
| PSMD1 | -5351 |
| ZSWIM8 | -5267 |
| RPL19 | -5254 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| ETF1 | -6952 |
| RNPS1 | -6938 |
| GSPT1 | -6825 |
| PSMF1 | -6663 |
| PSME4 | -6450 |
| PSMD2 | -6435 |
| UPF3A | -6189 |
| CASC3 | -5986 |
| PSMD6 | -5951 |
| EIF4G1 | -5901 |
| PSMA2 | -5801 |
| PSMA1 | -5730 |
| ROBO1 | -5577 |
| PSMC1 | -5564 |
| PSMD3 | -5535 |
| PSME2 | -5481 |
| PSMD1 | -5351 |
| ZSWIM8 | -5267 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| PSMB6 | -4888 |
| PSMC6 | -4878 |
| PSMC4 | -4808 |
| RPS5 | -4778 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| PSMD9 | -4638 |
| RPLP1 | -4391 |
| PSMB7 | -4372 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| UBB | -4263 |
| PSMA4 | -4211 |
| RPL35A | -4159 |
| PSMC5 | -4091 |
| RPL30 | -4081 |
| RPS9 | -4028 |
| RPL18 | -3961 |
| RPL26L1 | -3873 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| UPF2 | -3830 |
| PSME3 | -3813 |
| RBX1 | -3714 |
| RPL28 | -3546 |
| PABPC1 | -3543 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| SEM1 | -3130 |
| PSMA3 | -3078 |
| RPS15A | -3019 |
| ELOB | -3004 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| PSMD8 | -2928 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| RPS27A | -2773 |
| PSMA5 | -2715 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RPS13 | -2581 |
| PSMD13 | -2577 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| PSMC2 | -2389 |
| PSME1 | -2348 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| DAG1 | -2174 |
| NCBP1 | -2151 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| PSMB3 | -1915 |
| RPL23 | -1913 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| RBM8A | -1583 |
| PSMC3 | -1509 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| PSMB4 | -1144 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| MAGOH | -969 |
| RPS25 | -937 |
| PSMA7 | -892 |
| PSMB5 | -742 |
| RPL13 | -706 |
| RPL5 | -495 |
| PSMD11 | -432 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| PSMA6 | -126 |
| RPL9 | 261 |
| RPL31 | 330 |
| CUL2 | 359 |
| RPS26 | 419 |
| PSMB10 | 423 |
| ELOC | 645 |
| UBC | 779 |
| SLIT1 | 886 |
| PSMB1 | 1054 |
| EIF4A3 | 1154 |
| RPL21 | 1385 |
| PSMB2 | 1876 |
| LDB1 | 1882 |
| USP33 | 1924 |
| RPL22 | 2142 |
| UPF3B | 2326 |
| HOXA2 | 2735 |
| RPL36A | 2875 |
| PSMD12 | 4303 |
| MSI1 | 4326 |
| PSMD4 | 4567 |
| ROBO3 | 4691 |
| PSMD10 | 4933 |
| PSMD7 | 4942 |
| PSMD5 | 5116 |
| PSMB9 | 5491 |
| MAGOHB | 5814 |
| PSMD14 | 5974 |
| COL4A5 | 6694 |
| NCBP2 | 6823 |
Signaling by ROBO receptors
| 1145 | |
|---|---|
| set | Signaling by ROBO receptors |
| setSize | 193 |
| pANOVA | 2.58e-12 |
| s.dist | -0.293 |
| p.adjustANOVA | 1.87e-10 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| VASP | -7075 |
| RPL36AL | -6981 |
| ETF1 | -6952 |
| RNPS1 | -6938 |
| GSPT1 | -6825 |
| PSMF1 | -6663 |
| PSME4 | -6450 |
| PSMD2 | -6435 |
| ARHGAP39 | -6303 |
| PFN1 | -6285 |
| UPF3A | -6189 |
| CASC3 | -5986 |
| PSMD6 | -5951 |
| MYO9B | -5920 |
| EIF4G1 | -5901 |
| PSMA2 | -5801 |
| PSMA1 | -5730 |
| ROBO1 | -5577 |
| PSMC1 | -5564 |
| PSMD3 | -5535 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| VASP | -7075 |
| RPL36AL | -6981 |
| ETF1 | -6952 |
| RNPS1 | -6938 |
| GSPT1 | -6825 |
| PSMF1 | -6663 |
| PSME4 | -6450 |
| PSMD2 | -6435 |
| ARHGAP39 | -6303 |
| PFN1 | -6285 |
| UPF3A | -6189 |
| CASC3 | -5986 |
| PSMD6 | -5951 |
| MYO9B | -5920 |
| EIF4G1 | -5901 |
| PSMA2 | -5801 |
| PSMA1 | -5730 |
| ROBO1 | -5577 |
| PSMC1 | -5564 |
| PSMD3 | -5535 |
| PSME2 | -5481 |
| SOS2 | -5417 |
| PAK4 | -5359 |
| PSMD1 | -5351 |
| RHOA | -5294 |
| ZSWIM8 | -5267 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| PAK2 | -4957 |
| PSMB6 | -4888 |
| PSMC6 | -4878 |
| PSMC4 | -4808 |
| RPS5 | -4778 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| PSMD9 | -4638 |
| RPLP1 | -4391 |
| PSMB7 | -4372 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| UBB | -4263 |
| CLASP2 | -4246 |
| PSMA4 | -4211 |
| RPL35A | -4159 |
| PSMC5 | -4091 |
| CAP1 | -4085 |
| RPL30 | -4081 |
| PPP3CB | -4060 |
| RPS9 | -4028 |
| RPL18 | -3961 |
| NCK2 | -3916 |
| RPL26L1 | -3873 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| UPF2 | -3830 |
| PSME3 | -3813 |
| RBX1 | -3714 |
| RPL28 | -3546 |
| PABPC1 | -3543 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| ENAH | -3139 |
| SEM1 | -3130 |
| PSMA3 | -3078 |
| ABL2 | -3020 |
| RPS15A | -3019 |
| ELOB | -3004 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| PSMD8 | -2928 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| RPS27A | -2773 |
| PSMA5 | -2715 |
| CAP2 | -2694 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RPS13 | -2581 |
| PSMD13 | -2577 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| PSMC2 | -2389 |
| PSME1 | -2348 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| DAG1 | -2174 |
| CDC42 | -2172 |
| NCBP1 | -2151 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| PSMB3 | -1915 |
| RPL23 | -1913 |
| RPL24 | -1804 |
| SRGAP1 | -1796 |
| RPL38 | -1791 |
| SRGAP2 | -1779 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| RBM8A | -1583 |
| PSMC3 | -1509 |
| PRKACB | -1429 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| PSMB4 | -1144 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| MAGOH | -969 |
| SOS1 | -950 |
| RPS25 | -937 |
| PSMA7 | -892 |
| PRKAR2A | -860 |
| PSMB5 | -742 |
| RPL13 | -706 |
| RPL5 | -495 |
| PSMD11 | -432 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| PSMA6 | -126 |
| RAC1 | 44 |
| RPL9 | 261 |
| RPL31 | 330 |
| CUL2 | 359 |
| RPS26 | 419 |
| PSMB10 | 423 |
| ELOC | 645 |
| UBC | 779 |
| SLIT1 | 886 |
| PAK1 | 1031 |
| PSMB1 | 1054 |
| EIF4A3 | 1154 |
| NRP1 | 1353 |
| RPL21 | 1385 |
| NCK1 | 1525 |
| CLASP1 | 1561 |
| PRKACA | 1736 |
| PSMB2 | 1876 |
| LDB1 | 1882 |
| USP33 | 1924 |
| ABL1 | 2023 |
| RPL22 | 2142 |
| UPF3B | 2326 |
| PRKCA | 2439 |
| EVL | 2467 |
| HOXA2 | 2735 |
| RPL36A | 2875 |
| AKAP5 | 3035 |
| SRC | 3962 |
| PSMD12 | 4303 |
| MSI1 | 4326 |
| PSMD4 | 4567 |
| ROBO3 | 4691 |
| PSMD10 | 4933 |
| PSMD7 | 4942 |
| PSMD5 | 5116 |
| GPC1 | 5178 |
| PSMB9 | 5491 |
| MAGOHB | 5814 |
| PSMD14 | 5974 |
| COL4A5 | 6694 |
| SRGAP3 | 6775 |
| NCBP2 | 6823 |
| PFN2 | 6877 |
| FLRT3 | 7184 |
Diseases of signal transduction by growth factor receptors and second messengers
| 286 | |
|---|---|
| set | Diseases of signal transduction by growth factor receptors and second messengers |
| setSize | 361 |
| pANOVA | 3.78e-12 |
| s.dist | -0.214 |
| p.adjustANOVA | 2.6e-10 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SEL1L | -7124 |
| SYVN1 | -7108 |
| ARRB1 | -7062 |
| DERL2 | -7046 |
| EIF2AK3 | -7028 |
| SQSTM1 | -7010 |
| OS9 | -6986 |
| PEBP1 | -6972 |
| PIK3AP1 | -6957 |
| JAG1 | -6948 |
| TGFB1 | -6934 |
| SHC1 | -6910 |
| MAML1 | -6891 |
| MET | -6878 |
| PDGFRB | -6820 |
| VCP | -6720 |
| PSMF1 | -6663 |
| RRBP1 | -6551 |
| EP300 | -6470 |
| PSME4 | -6450 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SEL1L | -7124 |
| SYVN1 | -7108 |
| ARRB1 | -7062 |
| DERL2 | -7046 |
| EIF2AK3 | -7028 |
| SQSTM1 | -7010 |
| OS9 | -6986 |
| PEBP1 | -6972 |
| PIK3AP1 | -6957 |
| JAG1 | -6948 |
| TGFB1 | -6934 |
| SHC1 | -6910 |
| MAML1 | -6891 |
| MET | -6878 |
| PDGFRB | -6820 |
| VCP | -6720 |
| PSMF1 | -6663 |
| RRBP1 | -6551 |
| EP300 | -6470 |
| PSME4 | -6450 |
| PSMD2 | -6435 |
| BCL2L1 | -6349 |
| LCK | -6250 |
| CLTC | -6220 |
| FGFR1OP2 | -6202 |
| FGFR1 | -6191 |
| ERLEC1 | -6168 |
| TLN1 | -6146 |
| SMAD3 | -6145 |
| BAD | -6118 |
| MAP2K2 | -6087 |
| KDM7A | -6055 |
| SND1 | -6000 |
| AKT1S1 | -5990 |
| PSMD6 | -5951 |
| MAPKAP1 | -5936 |
| FIP1L1 | -5876 |
| ADAM17 | -5836 |
| PSMA2 | -5801 |
| KIAA1549 | -5776 |
| SEC31A | -5766 |
| PPP2R5A | -5740 |
| PSMA1 | -5730 |
| CBL | -5708 |
| STAT1 | -5668 |
| IQGAP1 | -5663 |
| SNW1 | -5581 |
| PSMC1 | -5564 |
| RAF1 | -5557 |
| HRAS | -5543 |
| PSMD3 | -5535 |
| DKK4 | -5490 |
| PSME2 | -5481 |
| LRRFIP1 | -5477 |
| POLR2L | -5471 |
| IRS2 | -5461 |
| QKI | -5427 |
| KIF5B | -5426 |
| PPM1B | -5398 |
| EGFR | -5383 |
| STRN | -5363 |
| PSMD1 | -5351 |
| CSNK1A1 | -5349 |
| TFG | -5336 |
| PTPN12 | -5326 |
| POLR2F | -5283 |
| DUSP10 | -5271 |
| CASP9 | -5247 |
| ARAF | -5242 |
| FKBP1A | -5189 |
| CDC37 | -5178 |
| PPP2CA | -5168 |
| PPP2R5B | -5131 |
| GSK3B | -5101 |
| UBA52 | -5068 |
| MAPK1 | -5066 |
| CTBP2 | -4982 |
| PSEN1 | -4938 |
| PHB | -4920 |
| SPTBN1 | -4901 |
| MECP2 | -4891 |
| PSMB6 | -4888 |
| TRIM24 | -4887 |
| PSMC6 | -4878 |
| AREG | -4847 |
| PSMC4 | -4808 |
| FXR1 | -4803 |
| KAT2B | -4792 |
| TNKS | -4790 |
| CPSF6 | -4789 |
| PIK3CD | -4759 |
| BRAF | -4749 |
| PPP2R1A | -4744 |
| MYH9 | -4726 |
| PTEN | -4721 |
| POLR2E | -4667 |
| PSMD9 | -4638 |
| GOLGA4 | -4624 |
| LRP6 | -4613 |
| PPP2CB | -4523 |
| TGFA | -4511 |
| NCOR2 | -4409 |
| HBEGF | -4402 |
| PIK3R1 | -4376 |
| NCOR1 | -4374 |
| PSMB7 | -4372 |
| MIB2 | -4356 |
| CDK8 | -4276 |
| MAP3K11 | -4272 |
| UBB | -4263 |
| IHH | -4252 |
| AXIN1 | -4215 |
| PSMA4 | -4211 |
| CUL1 | -4129 |
| GAB2 | -4127 |
| MAP2K1 | -4120 |
| CSK | -4113 |
| PIM1 | -4092 |
| PSMC5 | -4091 |
| SMAD2 | -4087 |
| HDAC5 | -4034 |
| FGF17 | -4015 |
| MARK3 | -3996 |
| PPFIBP1 | -3970 |
| NOTCH1 | -3923 |
| SPRED3 | -3905 |
| RPS6KB2 | -3901 |
| CREBBP | -3888 |
| DUSP7 | -3870 |
| HEY1 | -3864 |
| BCL2L11 | -3834 |
| PSME3 | -3813 |
| KLB | -3807 |
| FRS2 | -3790 |
| LMNA | -3717 |
| RBX1 | -3714 |
| POLR2B | -3699 |
| GSK3A | -3684 |
| MTOR | -3683 |
| TGFBR2 | -3644 |
| PPP1CB | -3630 |
| EEF1G | -3612 |
| POLR2H | -3593 |
| CDKN1A | -3580 |
| JUNB | -3526 |
| GOLGB1 | -3498 |
| POLR2C | -3425 |
| PPP1CC | -3392 |
| DUSP6 | -3376 |
| CHUK | -3364 |
| SHH | -3305 |
| ARRB2 | -3248 |
| TNKS2 | -3213 |
| SEM1 | -3130 |
| FN1 | -3115 |
| GTF2F1 | -3103 |
| PSMA3 | -3078 |
| BIRC6 | -3068 |
| GRB2 | -3047 |
| LYN | -3038 |
| AKT1 | -2958 |
| PSMD8 | -2928 |
| SPRED2 | -2862 |
| PIK3CA | -2813 |
| FGFR4 | -2795 |
| RPS27A | -2773 |
| RHOG | -2756 |
| JAK2 | -2719 |
| PSMA5 | -2715 |
| RPS6 | -2681 |
| HDAC1 | -2676 |
| ADAM10 | -2671 |
| PDGFA | -2660 |
| TGFBR1 | -2620 |
| PIK3CB | -2588 |
| PSMD13 | -2577 |
| SPRED1 | -2574 |
| FBXW7 | -2564 |
| PSEN2 | -2559 |
| BCR | -2502 |
| CCNC | -2471 |
| TSC2 | -2462 |
| PSMC2 | -2389 |
| PSME1 | -2348 |
| PSENEN | -2327 |
| LRP5 | -2319 |
| ERBIN | -2316 |
| PIK3R3 | -2279 |
| NCBP1 | -2151 |
| PPP2R5D | -2117 |
| PRR5 | -2094 |
| FOXO4 | -2077 |
| RICTOR | -2076 |
| KRAS | -2044 |
| NPM1 | -2033 |
| AKT2 | -1946 |
| PSMB3 | -1915 |
| APC | -1818 |
| DUSP16 | -1750 |
| CUX1 | -1665 |
| DCTN1 | -1635 |
| TBL1X | -1621 |
| ETV6 | -1588 |
| PSMC3 | -1509 |
| HDAC4 | -1478 |
| HDAC10 | -1408 |
| PIK3R2 | -1355 |
| YES1 | -1340 |
| LMO7 | -1246 |
| FGFR3 | -1195 |
| PSMB4 | -1144 |
| CEBPB | -1129 |
| HSP90AA1 | -1030 |
| TRIP11 | -990 |
| MDM2 | -956 |
| SOS1 | -950 |
| PSMA7 | -892 |
| PTPN11 | -867 |
| TPM4 | -822 |
| KREMEN2 | -791 |
| CDKN1B | -786 |
| SHOC2 | -749 |
| PSMB5 | -742 |
| ITGA2B | -688 |
| CALM1 | -655 |
| POLR2J | -603 |
| GCC2 | -597 |
| NCSTN | -554 |
| SKP1 | -544 |
| ATIC | -520 |
| JAG2 | -516 |
| CD19 | -472 |
| PSMD11 | -432 |
| HDAC2 | -338 |
| DUSP9 | -284 |
| MPRIP | -266 |
| PSMA6 | -126 |
| CTBP1 | -41 |
| TPM3 | -40 |
| RANBP2 | -4 |
| KSR1 | -1 |
| PRKAR1A | 4 |
| AP3B1 | 13 |
| EML4 | 27 |
| HDAC3 | 38 |
| RAC1 | 44 |
| KITLG | 92 |
| HDAC7 | 130 |
| PPP2R5E | 283 |
| RAP1A | 309 |
| PORCN | 320 |
| FGF5 | 342 |
| KREMEN1 | 364 |
| PDPK1 | 399 |
| PSMB10 | 423 |
| CREB1 | 474 |
| WDR48 | 543 |
| TPR | 565 |
| APH1A | 619 |
| UBC | 779 |
| TCF7L2 | 959 |
| HDAC11 | 1004 |
| PSMB1 | 1054 |
| RNF43 | 1197 |
| BRAP | 1211 |
| TBL1XR1 | 1404 |
| ZFYVE9 | 1407 |
| GAB1 | 1575 |
| NF1 | 1648 |
| MIB1 | 1650 |
| CAMK2D | 1711 |
| MLST8 | 1875 |
| PSMB2 | 1876 |
| MYC | 1892 |
| VWF | 1933 |
| FYN | 1937 |
| POLR2G | 2003 |
| AGK | 2062 |
| YWHAB | 2082 |
| FGF23 | 2097 |
| FRS3 | 2112 |
| CAMK2G | 2145 |
| FZD8 | 2263 |
| FOXO3 | 2282 |
| NRAS | 2310 |
| POLR2D | 2418 |
| PLCG1 | 2511 |
| POLR2A | 2705 |
| SMAD4 | 2742 |
| PPP2R5C | 2743 |
| ZMYM2 | 2755 |
| AGGF1 | 3135 |
| CLCN6 | 3165 |
| CTNNB1 | 3272 |
| ESR2 | 3316 |
| EREG | 3467 |
| IRS1 | 3502 |
| RAP1B | 3577 |
| TRAK1 | 3646 |
| CNKSR1 | 3649 |
| NR4A1 | 3691 |
| PAPSS1 | 3746 |
| NEURL1B | 3778 |
| HDAC8 | 3835 |
| MYO18A | 3903 |
| SRC | 3962 |
| BAG4 | 4019 |
| HHAT | 4068 |
| ERBB3 | 4249 |
| STAT3 | 4253 |
| PSMD12 | 4303 |
| VCL | 4407 |
| DKK1 | 4410 |
| ZC3HAV1 | 4414 |
| GTF2F2 | 4556 |
| CAMK2A | 4566 |
| PSMD4 | 4567 |
| POLR2I | 4594 |
| KLC1 | 4611 |
| PPP2R1B | 4614 |
| RBPJ | 4794 |
| KANK1 | 4837 |
| FZD5 | 4841 |
| DUSP8 | 4879 |
| PSMD10 | 4933 |
| PSMD7 | 4942 |
| AMER1 | 5007 |
| KAT2A | 5077 |
| AKAP9 | 5113 |
| PSMD5 | 5116 |
| MRAS | 5118 |
| STAT5A | 5288 |
| ERLIN2 | 5405 |
| FOXO1 | 5418 |
| ATG7 | 5453 |
| PSMB9 | 5491 |
| ERBB2 | 5534 |
| RNF213 | 5584 |
| ZC3HC1 | 5790 |
| AGTRAP | 5793 |
| HDAC6 | 5953 |
| POLR2K | 5962 |
| PSMD14 | 5974 |
| FLT3LG | 6000 |
| APH1B | 6168 |
| FZD6 | 6312 |
| FAM114A2 | 6340 |
| CNTRL | 6358 |
| FZD4 | 6534 |
| STAT5B | 6572 |
| WDCP | 6637 |
| MAPK3 | 6640 |
| FGG | 6697 |
| FGFR2 | 6811 |
| NCBP2 | 6823 |
| MAML2 | 6847 |
| PDGFB | 6920 |
| FGB | 7226 |
| HES1 | 7265 |
| HIP1 | 7319 |
| FGA | 7336 |
Response of EIF2AK4 (GCN2) to amino acid deficiency
| 1007 | |
|---|---|
| set | Response of EIF2AK4 (GCN2) to amino acid deficiency |
| setSize | 98 |
| pANOVA | 7.59e-12 |
| s.dist | -0.4 |
| p.adjustANOVA | 4.98e-10 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| DDIT3 | -7047 |
| RPL36AL | -6981 |
| TRIB3 | -6798 |
| ATF2 | -6175 |
| CEBPG | -5987 |
| ATF4 | -5664 |
| RPL19 | -5254 |
| EIF2S1 | -5190 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| GCN1 | -4627 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| DDIT3 | -7047 |
| RPL36AL | -6981 |
| TRIB3 | -6798 |
| ATF2 | -6175 |
| CEBPG | -5987 |
| ATF4 | -5664 |
| RPL19 | -5254 |
| EIF2S1 | -5190 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| GCN1 | -4627 |
| EIF2S2 | -4458 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| RPL30 | -4081 |
| RPS9 | -4028 |
| RPL18 | -3961 |
| RPL26L1 | -3873 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| EIF2S3 | -3669 |
| RPL28 | -3546 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| RPS15A | -3019 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| RPS27A | -2773 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| RPL23 | -1913 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| EIF2AK4 | -1455 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| CEBPB | -1129 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| RPS25 | -937 |
| RPL13 | -706 |
| RPL5 | -495 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPS26 | 419 |
| RPL21 | 1385 |
| RPL22 | 2142 |
| ATF3 | 2488 |
| RPL36A | 2875 |
| IMPACT | 4432 |
| ASNS | 6208 |
Formation of a pool of free 40S subunits
| 377 | |
|---|---|
| set | Formation of a pool of free 40S subunits |
| setSize | 98 |
| pANOVA | 1.12e-11 |
| s.dist | -0.397 |
| p.adjustANOVA | 6.94e-10 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| EIF3A | -6965 |
| EIF3I | -5279 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| EIF3B | -5127 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| EIF3G | -4724 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| EIF3J | -4539 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| EIF3A | -6965 |
| EIF3I | -5279 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| EIF3B | -5127 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| EIF3G | -4724 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| EIF3J | -4539 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| EIF3M | -4358 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| RPL30 | -4081 |
| RPS9 | -4028 |
| RPL18 | -3961 |
| RPL26L1 | -3873 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| EIF3D | -3740 |
| RPL28 | -3546 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| RPS15A | -3019 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| RPS27A | -2773 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| EIF3L | -2407 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| EIF3K | -2206 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| RPL23 | -1913 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| RPS25 | -937 |
| EIF3F | -893 |
| RPL13 | -706 |
| RPL5 | -495 |
| EIF3C | -374 |
| EIF1AX | -274 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPS26 | 419 |
| EIF3H | 899 |
| RPL21 | 1385 |
| RPL22 | 2142 |
| RPL36A | 2875 |
| EIF3E | 3244 |
Metabolism of RNA
| 618 | |
|---|---|
| set | Metabolism of RNA |
| setSize | 658 |
| pANOVA | 1.16e-11 |
| s.dist | -0.156 |
| p.adjustANOVA | 6.94e-10 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CNOT10 | -7014 |
| EIF4A1 | -6995 |
| ADAT3 | -6988 |
| SNRPA1 | -6983 |
| RPL36AL | -6981 |
| ETF1 | -6952 |
| RNPS1 | -6938 |
| DDX39A | -6895 |
| HNRNPM | -6829 |
| MPHOSPH10 | -6827 |
| GSPT1 | -6825 |
| SRSF4 | -6822 |
| ZFP36L1 | -6818 |
| ALYREF | -6816 |
| SEC13 | -6812 |
| DDX49 | -6809 |
| HNRNPF | -6735 |
| PATL1 | -6707 |
| DDX5 | -6665 |
| PSMF1 | -6663 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CNOT10 | -7014 |
| EIF4A1 | -6995 |
| ADAT3 | -6988 |
| SNRPA1 | -6983 |
| RPL36AL | -6981 |
| ETF1 | -6952 |
| RNPS1 | -6938 |
| DDX39A | -6895 |
| HNRNPM | -6829 |
| MPHOSPH10 | -6827 |
| GSPT1 | -6825 |
| SRSF4 | -6822 |
| ZFP36L1 | -6818 |
| ALYREF | -6816 |
| SEC13 | -6812 |
| DDX49 | -6809 |
| HNRNPF | -6735 |
| PATL1 | -6707 |
| DDX5 | -6665 |
| PSMF1 | -6663 |
| XPOT | -6616 |
| SNRPA | -6516 |
| HNRNPA3 | -6510 |
| ZFP36 | -6509 |
| EXOSC6 | -6503 |
| RAN | -6476 |
| MAPKAPK2 | -6461 |
| PSME4 | -6450 |
| HNRNPA2B1 | -6445 |
| PSMD2 | -6435 |
| CNOT3 | -6386 |
| RRP36 | -6354 |
| POM121 | -6353 |
| DHX38 | -6333 |
| RIOK3 | -6332 |
| SNRNP48 | -6317 |
| NXF1 | -6277 |
| TNPO1 | -6263 |
| UTP14C | -6243 |
| SRRT | -6216 |
| UPF3A | -6189 |
| SYF2 | -6169 |
| PRCC | -6133 |
| SLBP | -6130 |
| UTP4 | -6111 |
| POM121C | -6045 |
| CNOT8 | -6043 |
| PTBP1 | -6035 |
| SNRPD3 | -5999 |
| CASC3 | -5986 |
| SRRM2 | -5973 |
| FYTTD1 | -5952 |
| PSMD6 | -5951 |
| PUF60 | -5927 |
| EIF4G1 | -5901 |
| EIF4B | -5898 |
| FIP1L1 | -5876 |
| TRMU | -5863 |
| GPRC5A | -5847 |
| PSMA2 | -5801 |
| UTP14A | -5799 |
| SUPT5H | -5767 |
| PNO1 | -5758 |
| NSUN2 | -5750 |
| GTF2H1 | -5744 |
| FTSJ1 | -5735 |
| PSMA1 | -5730 |
| CSNK1D | -5722 |
| USP39 | -5721 |
| PHAX | -5719 |
| PRKCD | -5638 |
| YBX1 | -5615 |
| PRPF3 | -5593 |
| CLP1 | -5588 |
| SNW1 | -5581 |
| PSMC1 | -5564 |
| PSMD3 | -5535 |
| TYW1 | -5525 |
| RTCB | -5521 |
| PSME2 | -5481 |
| SRSF1 | -5478 |
| LTV1 | -5474 |
| POLR2L | -5471 |
| CDK7 | -5444 |
| PSMD1 | -5351 |
| GNL3 | -5332 |
| POLR2F | -5283 |
| NUP205 | -5275 |
| ELAC2 | -5264 |
| RPL19 | -5254 |
| DHX37 | -5250 |
| SRSF3 | -5244 |
| RBMX | -5221 |
| NOP14 | -5209 |
| SNRNP40 | -5200 |
| PPP2CA | -5168 |
| SRSF9 | -5148 |
| RPS7 | -5138 |
| RRP1 | -5133 |
| DCP2 | -5125 |
| MTO1 | -5079 |
| UBA52 | -5068 |
| ACTB | -5057 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| BUD31 | -5011 |
| RPS15 | -5010 |
| NUP188 | -4991 |
| FAU | -4990 |
| RPL14 | -4978 |
| NOP10 | -4958 |
| NOL9 | -4954 |
| IMP4 | -4940 |
| PSMB6 | -4888 |
| PSMC6 | -4878 |
| CTU1 | -4818 |
| LSM1 | -4814 |
| PSMC4 | -4808 |
| EDC4 | -4795 |
| CNOT4 | -4794 |
| SART1 | -4784 |
| RPS5 | -4778 |
| NUP88 | -4777 |
| BMS1 | -4769 |
| EXOSC5 | -4766 |
| IGF2BP1 | -4754 |
| PPP2R1A | -4744 |
| NUP50 | -4733 |
| PRPF8 | -4723 |
| PPIL1 | -4712 |
| RPS11 | -4702 |
| UPF1 | -4700 |
| POLR2E | -4667 |
| SRSF10 | -4662 |
| RPS19 | -4661 |
| HSPA8 | -4654 |
| RPS28 | -4652 |
| PSMD9 | -4638 |
| IMP3 | -4633 |
| ZCCHC6 | -4631 |
| HSD17B10 | -4604 |
| DDX20 | -4581 |
| PARN | -4578 |
| SF1 | -4554 |
| UTP18 | -4476 |
| SEH1L | -4472 |
| RNGTT | -4400 |
| RPLP1 | -4391 |
| BOP1 | -4381 |
| PSMB7 | -4372 |
| RPS12 | -4367 |
| MT-ND1 | -4361 |
| WDR33 | -4359 |
| DDX1 | -4308 |
| RPL27A | -4297 |
| SF3B5 | -4294 |
| RPLP0 | -4290 |
| TEX10 | -4283 |
| UBB | -4263 |
| NHP2 | -4261 |
| CWC27 | -4256 |
| TRMT44 | -4221 |
| PQBP1 | -4220 |
| PSMA4 | -4211 |
| WDR43 | -4193 |
| SF3A1 | -4178 |
| RPL35A | -4159 |
| CD2BP2 | -4125 |
| SF3B3 | -4118 |
| DHX9 | -4112 |
| PCF11 | -4093 |
| PSMC5 | -4091 |
| RPL30 | -4081 |
| DDX47 | -4068 |
| HNRNPL | -4046 |
| RPS9 | -4028 |
| RIOK2 | -4018 |
| NT5C3B | -4014 |
| ZRSR2 | -4009 |
| PRPF40A | -4000 |
| ADAR | -3971 |
| RPL18 | -3961 |
| DDX52 | -3894 |
| CWC22 | -3881 |
| CPSF1 | -3880 |
| RBM22 | -3875 |
| RPL26L1 | -3873 |
| TRMT112 | -3869 |
| SMG8 | -3868 |
| NOP2 | -3859 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| UPF2 | -3830 |
| PSME3 | -3813 |
| CHERP | -3803 |
| NOL12 | -3773 |
| NOB1 | -3772 |
| NUP98 | -3764 |
| LSM7 | -3745 |
| DDX23 | -3721 |
| THOC5 | -3719 |
| HNRNPU | -3716 |
| POLR2B | -3699 |
| PCBP1 | -3633 |
| ISG20L2 | -3623 |
| EBNA1BP2 | -3613 |
| POLR2H | -3593 |
| RPL28 | -3546 |
| PABPC1 | -3543 |
| RPSA | -3520 |
| PES1 | -3505 |
| SNRNP70 | -3471 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| EXOSC3 | -3453 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| XRN2 | -3427 |
| POLR2C | -3425 |
| SMN1 | -3422 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| HSPB1 | -3343 |
| XRN1 | -3316 |
| SF3A2 | -3293 |
| CWC25 | -3271 |
| RPS14 | -3261 |
| PAPOLA | -3183 |
| RPS27L | -3180 |
| SNRPD2 | -3171 |
| RPS10 | -3155 |
| EDC3 | -3136 |
| C2orf49 | -3132 |
| SEM1 | -3130 |
| SARNP | -3109 |
| GTF2F1 | -3103 |
| POP1 | -3098 |
| RBM17 | -3092 |
| CNOT7 | -3082 |
| PSMA3 | -3078 |
| EFTUD2 | -3071 |
| SF3A3 | -3033 |
| RPS15A | -3019 |
| GAR1 | -3015 |
| U2AF1 | -2991 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| AKT1 | -2958 |
| SF3B4 | -2942 |
| PSMD8 | -2928 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| PELP1 | -2894 |
| TRMT6 | -2889 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| ELAVL1 | -2841 |
| UTP20 | -2811 |
| HNRNPK | -2808 |
| SMG1 | -2778 |
| ISY1 | -2774 |
| RPS27A | -2773 |
| CRNKL1 | -2736 |
| SMG7 | -2718 |
| PSMA5 | -2715 |
| FCF1 | -2713 |
| ZMAT5 | -2710 |
| TXNL4A | -2705 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| WTAP | -2646 |
| BYSL | -2637 |
| RPL41 | -2635 |
| DHX16 | -2633 |
| RRP9 | -2591 |
| RPS13 | -2581 |
| PSMD13 | -2577 |
| RPL4 | -2563 |
| CDC5L | -2511 |
| UTP15 | -2509 |
| CTU2 | -2497 |
| ERI1 | -2490 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| CNOT1 | -2405 |
| PSMC2 | -2389 |
| ZBTB8OS | -2366 |
| PSME1 | -2348 |
| IGF2BP2 | -2324 |
| RPL39 | -2270 |
| CPSF7 | -2243 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| NIP7 | -2165 |
| NCBP1 | -2151 |
| CDC40 | -2131 |
| RPS4Y1 | -2120 |
| WBP4 | -2099 |
| NXT1 | -2092 |
| RPL27 | -2070 |
| AQR | -2059 |
| GEMIN5 | -2043 |
| PABPN1 | -2037 |
| ERCC3 | -2013 |
| PWP2 | -2005 |
| DDX39B | -1996 |
| NUP214 | -1926 |
| PSMB3 | -1915 |
| RPL23 | -1913 |
| SNRNP200 | -1880 |
| XPO1 | -1864 |
| NCL | -1840 |
| UTP6 | -1836 |
| THOC2 | -1832 |
| RPL24 | -1804 |
| HNRNPA1 | -1795 |
| RPL38 | -1791 |
| PRPF38A | -1785 |
| DHX15 | -1757 |
| LSM10 | -1755 |
| RPS20 | -1754 |
| POP7 | -1753 |
| RPL26 | -1747 |
| PLRG1 | -1743 |
| SRSF11 | -1739 |
| SF3B2 | -1718 |
| SNRPB | -1707 |
| WBP11 | -1682 |
| MT-ND2 | -1660 |
| RBM8A | -1583 |
| DIS3 | -1573 |
| NOC4L | -1552 |
| FBL | -1548 |
| PSMC3 | -1509 |
| NDC1 | -1490 |
| SENP3 | -1399 |
| SNUPN | -1386 |
| CWC15 | -1362 |
| UTP11 | -1337 |
| HEATR1 | -1324 |
| SMG6 | -1323 |
| RPL15 | -1313 |
| PDCD7 | -1301 |
| TRA2B | -1257 |
| DKC1 | -1249 |
| TFIP11 | -1238 |
| PRMT5 | -1166 |
| RPL3 | -1165 |
| WDR4 | -1153 |
| NOP56 | -1145 |
| PSMB4 | -1144 |
| RPL17 | -1119 |
| PAN3 | -1113 |
| RPS8 | -1071 |
| HNRNPUL1 | -1055 |
| TNFSF13 | -1035 |
| KHSRP | -994 |
| U2AF2 | -987 |
| RPL12 | -983 |
| SMNDC1 | -978 |
| MAGOH | -969 |
| DDX46 | -967 |
| RCL1 | -942 |
| RPS25 | -937 |
| PSMA7 | -892 |
| YWHAZ | -885 |
| BCAS2 | -879 |
| TSR1 | -851 |
| TBL3 | -794 |
| MRM2 | -777 |
| PSMB5 | -742 |
| PHF5A | -729 |
| RPL13 | -706 |
| TP53RK | -693 |
| SRSF2 | -660 |
| ZCCHC11 | -659 |
| SMG5 | -654 |
| TRMT61A | -644 |
| POLR2J | -603 |
| ERCC2 | -583 |
| TRMT10A | -514 |
| RPL5 | -495 |
| TSR3 | -466 |
| PSMD11 | -432 |
| GTF2H4 | -406 |
| OSGEP | -368 |
| TRMT1 | -362 |
| SRRM1 | -354 |
| TYW5 | -351 |
| SF3B1 | -343 |
| EXOSC10 | -341 |
| NUP160 | -329 |
| NUP62 | -299 |
| THUMPD1 | -270 |
| DDX21 | -256 |
| PPIH | -247 |
| RPL22L1 | -214 |
| MNAT1 | -205 |
| RPS3A | -179 |
| RPS27 | -152 |
| SNU13 | -129 |
| PSMA6 | -126 |
| TYW3 | -105 |
| SNRPG | -99 |
| SYMPK | -77 |
| DDX6 | -74 |
| POP4 | -42 |
| RANBP2 | -4 |
| IGF2BP3 | 36 |
| DCP1A | 40 |
| CNOT2 | 52 |
| TSEN54 | 102 |
| TRIT1 | 156 |
| SNRNP25 | 217 |
| THOC1 | 221 |
| MAPK11 | 251 |
| RPL9 | 261 |
| SLU7 | 281 |
| RPL31 | 330 |
| PAIP1 | 377 |
| ZC3H11A | 394 |
| RPS26 | 419 |
| PSMB10 | 423 |
| WDR61 | 452 |
| TSEN34 | 469 |
| EXOSC8 | 472 |
| ADAT1 | 478 |
| TFB1M | 518 |
| TPR | 565 |
| SNRPB2 | 572 |
| SNRPN | 623 |
| SNRPC | 686 |
| MT-CO2 | 716 |
| CNOT6 | 732 |
| RBM28 | 771 |
| UBC | 779 |
| KRR1 | 924 |
| GEMIN8 | 928 |
| APOBEC3B | 954 |
| PCBP2 | 974 |
| MRM1 | 1041 |
| PPIL6 | 1052 |
| PSMB1 | 1054 |
| METTL1 | 1104 |
| URM1 | 1139 |
| EIF4A3 | 1154 |
| CSTF3 | 1177 |
| CDKAL1 | 1232 |
| SUGP1 | 1250 |
| RPP14 | 1309 |
| PPIE | 1333 |
| NUP133 | 1362 |
| RPL21 | 1385 |
| POLDIP3 | 1421 |
| RPP30 | 1439 |
| HNRNPR | 1444 |
| GCFC2 | 1481 |
| ADARB1 | 1506 |
| CSTF2 | 1521 |
| THOC7 | 1544 |
| WDR77 | 1552 |
| RPP38 | 1564 |
| CPSF4 | 1570 |
| MT-ND4L | 1652 |
| LSM2 | 1691 |
| RPP40 | 1770 |
| NSUN6 | 1776 |
| HNRNPC | 1814 |
| HSPA1A | 1835 |
| THG1L | 1859 |
| PSMB2 | 1876 |
| MYC | 1892 |
| ZNF473 | 1958 |
| NOL6 | 1999 |
| POLR2G | 2003 |
| RRP7A | 2006 |
| TNKS1BP1 | 2031 |
| HBS1L | 2038 |
| PRPF31 | 2039 |
| SNRNP27 | 2043 |
| FTSJ3 | 2052 |
| YWHAB | 2082 |
| PUS7 | 2099 |
| SET | 2106 |
| WDR18 | 2127 |
| RPL22 | 2142 |
| TGS1 | 2148 |
| DNAJC8 | 2214 |
| NUDT21 | 2243 |
| MAPK14 | 2269 |
| PRPF4 | 2278 |
| THOC3 | 2285 |
| UPF3B | 2326 |
| SNRPF | 2328 |
| TPRKB | 2341 |
| U2AF1L4 | 2349 |
| POP5 | 2364 |
| NUP58 | 2380 |
| DIMT1 | 2382 |
| POLR2D | 2418 |
| PRKCA | 2439 |
| EIF4E | 2473 |
| THADA | 2501 |
| GLE1 | 2507 |
| PPIL4 | 2522 |
| TRMT12 | 2539 |
| CSTF1 | 2549 |
| HNRNPH2 | 2555 |
| U2SURP | 2650 |
| SRSF7 | 2693 |
| POLR2A | 2705 |
| RIOK1 | 2711 |
| NUP153 | 2712 |
| PRPF19 | 2734 |
| MRM3 | 2765 |
| NUP43 | 2808 |
| RPL36A | 2875 |
| TRMT13 | 2920 |
| CCAR1 | 2925 |
| LAGE3 | 2937 |
| AAAS | 2965 |
| MT-ND6 | 3010 |
| SNRPE | 3034 |
| THOC6 | 3050 |
| CHTOP | 3093 |
| HNRNPD | 3107 |
| HNRNPH1 | 3111 |
| MT-ND4 | 3146 |
| TSEN2 | 3158 |
| TTC37 | 3159 |
| EXOSC4 | 3220 |
| CSNK1E | 3247 |
| EXOSC9 | 3293 |
| NUP54 | 3310 |
| PDCD11 | 3334 |
| MT-ND5 | 3335 |
| NAT10 | 3342 |
| GTPBP3 | 3375 |
| CTNNBL1 | 3386 |
| C1D | 3482 |
| EXOSC1 | 3486 |
| MT-ND3 | 3491 |
| WDR75 | 3573 |
| PPWD1 | 3615 |
| DCP1B | 3617 |
| PUS1 | 3715 |
| TRNT1 | 3774 |
| EXOSC2 | 3779 |
| WDR12 | 3814 |
| TRMT61B | 3833 |
| DUS2 | 3842 |
| CNOT11 | 3855 |
| GPKOW | 3887 |
| PRPF6 | 3945 |
| RNPC3 | 3974 |
| SMG9 | 3998 |
| NSUN4 | 4005 |
| NOL11 | 4020 |
| XAB2 | 4040 |
| NUP85 | 4178 |
| PUS3 | 4248 |
| GEMIN4 | 4278 |
| UTP3 | 4280 |
| PSMD12 | 4303 |
| GTF2H5 | 4373 |
| RAE1 | 4394 |
| RNMT | 4440 |
| QTRT2 | 4536 |
| GTF2F2 | 4556 |
| PSMD4 | 4567 |
| METTL14 | 4585 |
| POLR2I | 4594 |
| SKIV2L | 4599 |
| DCAF13 | 4652 |
| WDR46 | 4709 |
| ZCRB1 | 4731 |
| NUP155 | 4796 |
| METTL3 | 4870 |
| ALKBH8 | 4880 |
| LCMT2 | 4904 |
| PSMD10 | 4933 |
| PSMD7 | 4942 |
| TRMT10C | 4994 |
| TRDMT1 | 4998 |
| GEMIN7 | 5050 |
| PSMD5 | 5116 |
| LSM3 | 5148 |
| PPIL3 | 5149 |
| QTRT1 | 5195 |
| EXOSC7 | 5196 |
| LSM6 | 5218 |
| LSM5 | 5261 |
| GTF2H2 | 5321 |
| LSM8 | 5399 |
| GEMIN6 | 5443 |
| HNRNPA0 | 5448 |
| SF3B6 | 5469 |
| PSMB9 | 5491 |
| DCPS | 5495 |
| RBM5 | 5541 |
| CCNH | 5556 |
| EIF4A2 | 5593 |
| PNRC2 | 5595 |
| NOP58 | 5612 |
| MPHOSPH6 | 5619 |
| CNOT6L | 5623 |
| PPP2R2A | 5688 |
| TRMT11 | 5691 |
| WDR3 | 5692 |
| DDX42 | 5700 |
| WDR36 | 5735 |
| FAM98B | 5786 |
| MAGOHB | 5814 |
| NUP93 | 5831 |
| LSM11 | 5855 |
| SNRPD1 | 5905 |
| POLR2K | 5962 |
| PSMD14 | 5974 |
| NUP35 | 5982 |
| GTF2H3 | 6024 |
| NUP107 | 6076 |
| MT-ATP6 | 6186 |
| ADAT2 | 6214 |
| MTERF4 | 6222 |
| CPSF3 | 6257 |
| SRSF5 | 6261 |
| A1CF | 6295 |
| SRSF6 | 6395 |
| CPSF2 | 6432 |
| TSEN15 | 6489 |
| MT-CO1 | 6493 |
| CLNS1A | 6527 |
| MT-ATP8 | 6710 |
| GEMIN2 | 6729 |
| ENPP2 | 6800 |
| NUP210 | 6802 |
| NCBP2 | 6823 |
| TRMT5 | 6848 |
| CSTF2T | 6871 |
| LSM4 | 6899 |
| LAS1L | 7022 |
| NUP37 | 7100 |
| SNRNP35 | 7126 |
| PAN2 | 7162 |
| APOBEC3C | 7172 |
| MT-CYB | 7213 |
| FUS | 7280 |
| ANP32A | 7288 |
| MT-CO3 | 7316 |
| EMG1 | 7347 |
| IGF2 | 7375 |
Eukaryotic Translation Elongation
| 336 | |
|---|---|
| set | Eukaryotic Translation Elongation |
| setSize | 91 |
| pANOVA | 2.06e-11 |
| s.dist | -0.407 |
| p.adjustANOVA | 1.18e-09 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| EEF1D | -5115 |
| UBA52 | -5068 |
| EEF2 | -5049 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| EEF1B2 | -4836 |
| RPS5 | -4778 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| EEF1D | -5115 |
| UBA52 | -5068 |
| EEF2 | -5049 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| EEF1B2 | -4836 |
| RPS5 | -4778 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| EEF1A1 | -4138 |
| RPL30 | -4081 |
| RPS9 | -4028 |
| RPL18 | -3961 |
| RPL26L1 | -3873 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| EEF1G | -3612 |
| RPL28 | -3546 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| RPS15A | -3019 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| RPS27A | -2773 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| RPL23 | -1913 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| EEF1A1P5 | -1745 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| RPS25 | -937 |
| RPL13 | -706 |
| RPL5 | -495 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPS26 | 419 |
| EEF1A2 | 553 |
| RPL21 | 1385 |
| RPL22 | 2142 |
| RPL36A | 2875 |
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
| 722 | |
|---|---|
| set | Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) |
| setSize | 91 |
| pANOVA | 2.32e-11 |
| s.dist | -0.406 |
| p.adjustANOVA | 1.27e-09 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| ETF1 | -6952 |
| GSPT1 | -6825 |
| EIF4G1 | -5901 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| RPS11 | -4702 |
| UPF1 | -4700 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| RPL27A | -4297 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| ETF1 | -6952 |
| GSPT1 | -6825 |
| EIF4G1 | -5901 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| RPS11 | -4702 |
| UPF1 | -4700 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| RPL30 | -4081 |
| RPS9 | -4028 |
| RPL18 | -3961 |
| RPL26L1 | -3873 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| RPL28 | -3546 |
| PABPC1 | -3543 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| RPS15A | -3019 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| RPS27A | -2773 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| NCBP1 | -2151 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| RPL23 | -1913 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| RPS25 | -937 |
| RPL13 | -706 |
| RPL5 | -495 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPS26 | 419 |
| RPL21 | 1385 |
| RPL22 | 2142 |
| RPL36A | 2875 |
| NCBP2 | 6823 |
Disease
| 271 | |
|---|---|
| set | Disease |
| setSize | 1247 |
| pANOVA | 2.4e-11 |
| s.dist | -0.114 |
| p.adjustANOVA | 1.27e-09 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CALR | -7142 |
| DNAJC3 | -7131 |
| SLC2A1 | -7130 |
| SLC3A2 | -7128 |
| SEL1L | -7124 |
| SYVN1 | -7108 |
| CANX | -7092 |
| ANTXR2 | -7077 |
| SLC17A5 | -7072 |
| ARRB1 | -7062 |
| GFPT1 | -7051 |
| DERL2 | -7046 |
| MAGT1 | -7045 |
| MAP1LC3B | -7040 |
| RAMP1 | -7037 |
| EIF2AK3 | -7028 |
| RPN1 | -7013 |
| SLC33A1 | -7011 |
| SQSTM1 | -7010 |
| OS9 | -6986 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CALR | -7142 |
| DNAJC3 | -7131 |
| SLC2A1 | -7130 |
| SLC3A2 | -7128 |
| SEL1L | -7124 |
| SYVN1 | -7108 |
| CANX | -7092 |
| ANTXR2 | -7077 |
| SLC17A5 | -7072 |
| ARRB1 | -7062 |
| GFPT1 | -7051 |
| DERL2 | -7046 |
| MAGT1 | -7045 |
| MAP1LC3B | -7040 |
| RAMP1 | -7037 |
| EIF2AK3 | -7028 |
| RPN1 | -7013 |
| SLC33A1 | -7011 |
| SQSTM1 | -7010 |
| OS9 | -6986 |
| RPL36AL | -6981 |
| PEBP1 | -6972 |
| DVL3 | -6967 |
| PIK3AP1 | -6957 |
| CTSL | -6951 |
| JAG1 | -6948 |
| ATP1B3 | -6941 |
| ARSB | -6939 |
| TGFB1 | -6934 |
| SHC1 | -6910 |
| GCLC | -6903 |
| MAML1 | -6891 |
| MET | -6878 |
| SFPQ | -6854 |
| ACTG1 | -6841 |
| PDGFRB | -6820 |
| GNS | -6813 |
| SEC13 | -6812 |
| TXNRD1 | -6806 |
| ST3GAL4 | -6801 |
| ABCB4 | -6800 |
| STT3A | -6796 |
| POMT2 | -6788 |
| ATP1A1 | -6777 |
| NEU1 | -6752 |
| ST6GALNAC4 | -6726 |
| VCP | -6720 |
| KPNA1 | -6701 |
| FURIN | -6683 |
| PRDX1 | -6673 |
| SLC35C1 | -6667 |
| DDX5 | -6665 |
| PSMF1 | -6663 |
| RNF5 | -6629 |
| ATP1B1 | -6624 |
| PCCA | -6623 |
| ABCC2 | -6611 |
| SLC6A2 | -6609 |
| ALG3 | -6601 |
| HK1 | -6574 |
| CHMP4C | -6557 |
| ALG2 | -6554 |
| RRBP1 | -6551 |
| WASL | -6543 |
| APP | -6492 |
| VHL | -6491 |
| KEAP1 | -6482 |
| BRD4 | -6479 |
| RAN | -6476 |
| EP300 | -6470 |
| HEXB | -6455 |
| PSME4 | -6450 |
| CLTA | -6439 |
| NFKBIA | -6437 |
| PSMD2 | -6435 |
| DDOST | -6429 |
| DERL1 | -6423 |
| TCEA1 | -6409 |
| SPON2 | -6404 |
| P2RY11 | -6403 |
| MGAT1 | -6401 |
| NUS1 | -6395 |
| KPNB1 | -6379 |
| IPO5 | -6366 |
| RNF185 | -6359 |
| THSD4 | -6356 |
| POM121 | -6353 |
| BCL2L1 | -6349 |
| GALNS | -6314 |
| BRMS1 | -6309 |
| NT5E | -6296 |
| UVRAG | -6290 |
| CTSA | -6288 |
| FNTA | -6282 |
| MGAT4B | -6279 |
| LCK | -6250 |
| ABCD1 | -6246 |
| DAD1 | -6240 |
| SLC12A6 | -6223 |
| CLTC | -6220 |
| FGFR1OP2 | -6202 |
| LMBRD1 | -6198 |
| RPN2 | -6193 |
| FGFR1 | -6191 |
| ERLEC1 | -6168 |
| TLN1 | -6146 |
| SMAD3 | -6145 |
| BAD | -6118 |
| TAF4 | -6108 |
| ARPC4 | -6094 |
| ITPR3 | -6088 |
| MAP2K2 | -6087 |
| ALG12 | -6081 |
| ADM2 | -6068 |
| KDM7A | -6055 |
| DPAGT1 | -6046 |
| POM121C | -6045 |
| PTHLH | -6042 |
| ARF1 | -6021 |
| SND1 | -6000 |
| AKT1S1 | -5990 |
| ALG11 | -5957 |
| PSMD6 | -5951 |
| IKBKG | -5946 |
| MAPKAP1 | -5936 |
| PRKCSH | -5934 |
| MYO9B | -5920 |
| ST3GAL1 | -5905 |
| SIN3A | -5884 |
| FIP1L1 | -5876 |
| FXYD2 | -5865 |
| MGAT5 | -5854 |
| CAPN1 | -5850 |
| HTR7 | -5841 |
| ADAM17 | -5836 |
| GTF2E2 | -5813 |
| RAB7A | -5810 |
| FKBP4 | -5807 |
| PSMA2 | -5801 |
| KIAA1549 | -5776 |
| SUPT5H | -5767 |
| SEC31A | -5766 |
| GTF2H1 | -5744 |
| PPP2R5A | -5740 |
| ELK1 | -5733 |
| PSMA1 | -5730 |
| CYP27B1 | -5723 |
| WASF1 | -5712 |
| CBL | -5708 |
| GTF2B | -5704 |
| CBLL1 | -5694 |
| CHMP1A | -5693 |
| STAT1 | -5668 |
| IQGAP1 | -5663 |
| CRK | -5650 |
| VCAN | -5649 |
| EZH2 | -5631 |
| MTA2 | -5619 |
| SNW1 | -5581 |
| MCCC1 | -5566 |
| PSMC1 | -5564 |
| RAF1 | -5557 |
| TALDO1 | -5554 |
| HRAS | -5543 |
| PSMD3 | -5535 |
| EDEM2 | -5520 |
| DKK4 | -5490 |
| ISG15 | -5488 |
| PSME2 | -5481 |
| LRRFIP1 | -5477 |
| POLR2L | -5471 |
| IDH1 | -5470 |
| IRS2 | -5461 |
| CDK7 | -5444 |
| BRK1 | -5431 |
| QKI | -5427 |
| KIF5B | -5426 |
| B3GLCT | -5422 |
| RAB5A | -5408 |
| PPM1B | -5398 |
| EGFR | -5383 |
| PDCD6IP | -5380 |
| STRN | -5363 |
| PSMD1 | -5351 |
| CSNK1A1 | -5349 |
| TFG | -5336 |
| THSD1 | -5333 |
| PTPN12 | -5326 |
| GOLGA2 | -5310 |
| ACTR3 | -5296 |
| PC | -5292 |
| MYO10 | -5290 |
| NELFA | -5284 |
| POLR2F | -5283 |
| TAF13 | -5280 |
| NUP205 | -5275 |
| DUSP10 | -5271 |
| RPL19 | -5254 |
| CASP9 | -5247 |
| ARAF | -5242 |
| SAP30 | -5230 |
| HMGA1 | -5226 |
| PIK3C3 | -5220 |
| FKBP1A | -5189 |
| PMM2 | -5187 |
| CDC37 | -5178 |
| TBK1 | -5169 |
| PPP2CA | -5168 |
| RPS7 | -5138 |
| FUT8 | -5134 |
| PPP2R5B | -5131 |
| GSK3B | -5101 |
| VAMP2 | -5088 |
| SLC9A6 | -5075 |
| UBA52 | -5068 |
| MAPK1 | -5066 |
| CDK4 | -5064 |
| ACTB | -5057 |
| LARGE1 | -5056 |
| EEF2 | -5049 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| CHMP4B | -5021 |
| MGAT4A | -5018 |
| RPS15 | -5010 |
| PLK2 | -5005 |
| NUP188 | -4991 |
| FAU | -4990 |
| CTBP2 | -4982 |
| RPL14 | -4978 |
| JAK1 | -4963 |
| PAK2 | -4957 |
| ANAPC15 | -4945 |
| IL6R | -4943 |
| PSEN1 | -4938 |
| PHB | -4920 |
| SPTBN1 | -4901 |
| BSG | -4895 |
| MECP2 | -4891 |
| PSMB6 | -4888 |
| TRIM24 | -4887 |
| PSMC6 | -4878 |
| B3GALT6 | -4868 |
| ENO1 | -4866 |
| AREG | -4847 |
| TRIM27 | -4835 |
| CHD4 | -4830 |
| PGK1 | -4810 |
| PSMC4 | -4808 |
| FXR1 | -4803 |
| KAT2B | -4792 |
| TNKS | -4790 |
| CPSF6 | -4789 |
| RPS5 | -4778 |
| NUP88 | -4777 |
| IDS | -4768 |
| PIK3CD | -4759 |
| BRAF | -4749 |
| GRSF1 | -4747 |
| PPP2R1A | -4744 |
| NUP50 | -4733 |
| MYH9 | -4726 |
| PTEN | -4721 |
| RPS11 | -4702 |
| VPS37B | -4696 |
| CCNT1 | -4690 |
| POLR2E | -4667 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| VAV3 | -4642 |
| PSMD9 | -4638 |
| GOLGA4 | -4624 |
| VPS37C | -4620 |
| LRP6 | -4613 |
| GNAI3 | -4609 |
| AP2M1 | -4603 |
| PGM1 | -4600 |
| KPNA2 | -4575 |
| MBD3 | -4543 |
| SSRP1 | -4525 |
| GPS2 | -4524 |
| PPP2CB | -4523 |
| ST3GAL2 | -4518 |
| GNB2 | -4514 |
| TGFA | -4511 |
| MAP2K4 | -4505 |
| TAF4B | -4483 |
| ABI1 | -4478 |
| SEH1L | -4472 |
| CTDP1 | -4461 |
| VEGFA | -4456 |
| PPIA | -4443 |
| ARPC1B | -4429 |
| HSP90AB1 | -4426 |
| ATP6V1H | -4423 |
| CAPNS1 | -4414 |
| SLC34A3 | -4411 |
| NCOR2 | -4409 |
| HBEGF | -4402 |
| RNGTT | -4400 |
| MAP2K7 | -4399 |
| NAGLU | -4398 |
| RPLP1 | -4391 |
| PIK3R1 | -4376 |
| NCOR1 | -4374 |
| PSMB7 | -4372 |
| RPS12 | -4367 |
| KPNA3 | -4357 |
| MIB2 | -4356 |
| ALG1 | -4352 |
| PTK2 | -4346 |
| CHSY1 | -4336 |
| HEXA | -4335 |
| ITPR1 | -4321 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| PRMT1 | -4281 |
| CDK8 | -4276 |
| MAP3K11 | -4272 |
| UBB | -4263 |
| IHH | -4252 |
| CYP26B1 | -4218 |
| AXIN1 | -4215 |
| PSMA4 | -4211 |
| HGS | -4210 |
| BTD | -4207 |
| AP1S2 | -4204 |
| SH3GL1 | -4200 |
| VPS37A | -4187 |
| XRCC5 | -4164 |
| RPL35A | -4159 |
| ITGB1 | -4145 |
| CUL1 | -4129 |
| GAB2 | -4127 |
| MAP2K1 | -4120 |
| CSK | -4113 |
| GATAD2A | -4108 |
| PIM1 | -4092 |
| PSMC5 | -4091 |
| SMAD2 | -4087 |
| RPL30 | -4081 |
| RAD50 | -4078 |
| HDAC5 | -4034 |
| RPS9 | -4028 |
| GGCX | -4023 |
| FGF17 | -4015 |
| GGT5 | -4012 |
| NR3C1 | -4005 |
| SLC25A5 | -4001 |
| MARK3 | -3996 |
| PPFIBP1 | -3970 |
| RPL18 | -3961 |
| GBE1 | -3927 |
| TTR | -3924 |
| NOTCH1 | -3923 |
| POMT1 | -3914 |
| SPRED3 | -3905 |
| GNAI2 | -3904 |
| RPS6KB2 | -3901 |
| DYNC1LI2 | -3897 |
| CREBBP | -3888 |
| SAP30L | -3887 |
| RPL26L1 | -3873 |
| DUSP7 | -3870 |
| HEY1 | -3864 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| PARP16 | -3842 |
| CCND2 | -3838 |
| BCL2L11 | -3834 |
| PSME3 | -3813 |
| KLB | -3807 |
| FRS2 | -3790 |
| CYP27A1 | -3786 |
| CAPN2 | -3774 |
| PLCG2 | -3766 |
| NELFCD | -3765 |
| NUP98 | -3764 |
| SLC25A6 | -3733 |
| GNAZ | -3724 |
| LMNA | -3717 |
| RBX1 | -3714 |
| GPHA2 | -3711 |
| POLR2B | -3699 |
| ATP1B2 | -3692 |
| B4GAT1 | -3691 |
| GSK3A | -3684 |
| MTOR | -3683 |
| CD320 | -3680 |
| CD9 | -3660 |
| TGFBR2 | -3644 |
| PPP1CB | -3630 |
| MVB12B | -3629 |
| DYNC1H1 | -3614 |
| EEF1G | -3612 |
| TXN | -3611 |
| ROCK1 | -3594 |
| POLR2H | -3593 |
| CDKN1A | -3580 |
| MAN1B1 | -3561 |
| RPL28 | -3546 |
| JUNB | -3526 |
| DCXR | -3525 |
| RPSA | -3520 |
| NFKB1 | -3507 |
| MYO5A | -3500 |
| AP2A2 | -3499 |
| GOLGB1 | -3498 |
| RCOR1 | -3493 |
| ADAMTSL2 | -3475 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| POLR2C | -3425 |
| RPL37 | -3413 |
| PAH | -3408 |
| PPP1CC | -3392 |
| RBP1 | -3386 |
| DUSP6 | -3376 |
| RPS17 | -3369 |
| WASF2 | -3366 |
| CHUK | -3364 |
| RPS24 | -3352 |
| SAP18 | -3349 |
| MAP2K3 | -3342 |
| MGAT2 | -3327 |
| SHH | -3305 |
| RBBP4 | -3297 |
| MAOA | -3288 |
| RPS14 | -3261 |
| ARRB2 | -3248 |
| GNB1 | -3237 |
| GALNT3 | -3227 |
| SLC11A2 | -3217 |
| TNKS2 | -3213 |
| B3GAT3 | -3209 |
| ALG14 | -3206 |
| SLC25A4 | -3203 |
| HMG20B | -3184 |
| RPS27L | -3180 |
| DPEP1 | -3163 |
| RPS10 | -3155 |
| SEM1 | -3130 |
| FN1 | -3115 |
| GTF2F1 | -3103 |
| TRIM28 | -3099 |
| RHBDF2 | -3089 |
| PSMA3 | -3078 |
| BIRC6 | -3068 |
| CUL3 | -3056 |
| GRB2 | -3047 |
| LYN | -3038 |
| RPS15A | -3019 |
| ELOB | -3004 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| WIPF2 | -2965 |
| TAF5 | -2960 |
| AKT1 | -2958 |
| C1GALT1C1 | -2939 |
| JUN | -2934 |
| IKBKB | -2931 |
| PSMD8 | -2928 |
| RPS21 | -2927 |
| AP2S1 | -2922 |
| BECN1 | -2900 |
| RPS16 | -2898 |
| RIPK1 | -2886 |
| RPS3 | -2880 |
| TPST2 | -2873 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| SPRED2 | -2862 |
| RPL35 | -2849 |
| FXYD1 | -2847 |
| ELOA | -2831 |
| SUPT4H1 | -2826 |
| ADCY6 | -2818 |
| PIK3CA | -2813 |
| HNRNPK | -2808 |
| FGFR4 | -2795 |
| NCKAP1 | -2788 |
| DYNC1I2 | -2780 |
| ELMO1 | -2779 |
| RPS27A | -2773 |
| ROCK2 | -2772 |
| RHOG | -2756 |
| SLC35A2 | -2730 |
| JAK2 | -2719 |
| PSMA5 | -2715 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| CCND3 | -2677 |
| HDAC1 | -2676 |
| ADAM10 | -2671 |
| PDGFA | -2660 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RELA | -2632 |
| TGFBR1 | -2620 |
| SLC20A2 | -2599 |
| PIK3CB | -2588 |
| RPS13 | -2581 |
| TFDP1 | -2579 |
| PSMD13 | -2577 |
| SPRED1 | -2574 |
| FBXW7 | -2564 |
| RPL4 | -2563 |
| PSEN2 | -2559 |
| FNTB | -2551 |
| ADM | -2543 |
| B2M | -2523 |
| DYNC1LI1 | -2519 |
| BCR | -2502 |
| GNAI1 | -2495 |
| ABCB6 | -2491 |
| CCNC | -2471 |
| RPS23 | -2467 |
| TSC2 | -2462 |
| RPL37A | -2451 |
| ADAMTS17 | -2445 |
| PSMC2 | -2389 |
| TOP3A | -2378 |
| STX1A | -2377 |
| TLR9 | -2371 |
| AGRN | -2369 |
| MCCC2 | -2365 |
| MAP2K6 | -2351 |
| PSME1 | -2348 |
| PSENEN | -2327 |
| LRP5 | -2319 |
| ERBIN | -2316 |
| IFNAR2 | -2313 |
| NELFB | -2298 |
| TPMT | -2290 |
| ABCA1 | -2289 |
| SUDS3 | -2287 |
| PIK3R3 | -2279 |
| MOGS | -2275 |
| RPL39 | -2270 |
| DVL1 | -2264 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| ARPC2 | -2209 |
| DAG1 | -2174 |
| CDC42 | -2172 |
| RCC1 | -2159 |
| NCBP1 | -2151 |
| SDC4 | -2147 |
| EXT1 | -2144 |
| TSG101 | -2130 |
| TPST1 | -2126 |
| RPS4Y1 | -2120 |
| PPP2R5D | -2117 |
| DPM2 | -2111 |
| NFE2L2 | -2108 |
| PRR5 | -2094 |
| NMT1 | -2085 |
| FOXO4 | -2077 |
| RICTOR | -2076 |
| RPL27 | -2070 |
| SLC40A1 | -2061 |
| KRAS | -2044 |
| PABPN1 | -2037 |
| NPM1 | -2033 |
| CCNE2 | -2024 |
| TP53 | -2020 |
| ERCC3 | -2013 |
| DBP | -2002 |
| TICAM1 | -1956 |
| AKT2 | -1946 |
| AHCY | -1945 |
| SLC22A5 | -1944 |
| CRBN | -1928 |
| NUP214 | -1926 |
| AP1G1 | -1916 |
| PSMB3 | -1915 |
| RPL23 | -1913 |
| SRPK2 | -1905 |
| AP2A1 | -1902 |
| SLC2A9 | -1899 |
| UBAP1 | -1894 |
| UBE2S | -1872 |
| XPO1 | -1864 |
| ST6GAL1 | -1828 |
| APC | -1818 |
| IMPDH1 | -1807 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| HLCS | -1769 |
| SLC3A1 | -1764 |
| RPS20 | -1754 |
| DUSP16 | -1750 |
| RPL26 | -1747 |
| CHMP5 | -1722 |
| ATP1A3 | -1706 |
| KPNA4 | -1701 |
| CUX1 | -1665 |
| ANAPC2 | -1639 |
| DCTN1 | -1635 |
| TBL1X | -1621 |
| ETV6 | -1588 |
| PARP6 | -1567 |
| ANAPC11 | -1544 |
| CDC27 | -1529 |
| MUC13 | -1524 |
| ARPC5 | -1511 |
| PSMC3 | -1509 |
| NDC1 | -1490 |
| HDAC4 | -1478 |
| NAPEPLD | -1467 |
| ELL | -1439 |
| PRKACB | -1429 |
| HDAC10 | -1408 |
| LFNG | -1376 |
| PIK3R2 | -1355 |
| CDK5 | -1352 |
| YES1 | -1340 |
| LY96 | -1339 |
| CHD3 | -1321 |
| UBE2I | -1318 |
| RPL15 | -1313 |
| NFKB2 | -1311 |
| LMO7 | -1246 |
| DPM1 | -1233 |
| CUL5 | -1229 |
| TAF3 | -1222 |
| TUSC3 | -1219 |
| MYO1C | -1212 |
| SNF8 | -1198 |
| ABI2 | -1197 |
| FGFR3 | -1195 |
| GYG1 | -1167 |
| RPL3 | -1165 |
| PSMB4 | -1144 |
| CEBPB | -1129 |
| RPL17 | -1119 |
| SLC27A4 | -1101 |
| GATAD2B | -1092 |
| ADAMTSL5 | -1090 |
| CCNK | -1089 |
| CHMP2A | -1088 |
| PHF21A | -1078 |
| RPS8 | -1071 |
| MAN2A1 | -1040 |
| PRKAR1B | -1038 |
| HSP90AA1 | -1030 |
| MUC20 | -1019 |
| TAF7 | -1012 |
| GNB3 | -1008 |
| TRIP11 | -990 |
| RPL12 | -983 |
| NCKAP1L | -972 |
| PRDX2 | -961 |
| MDM2 | -956 |
| SOS1 | -950 |
| RPS25 | -937 |
| VPS4B | -934 |
| SH3KBP1 | -917 |
| DVL2 | -905 |
| PSMA7 | -892 |
| AMN | -881 |
| CHMP2B | -878 |
| PTPN11 | -867 |
| PRKAR2A | -860 |
| TPM4 | -822 |
| GALNT1 | -816 |
| KREMEN2 | -791 |
| CDKN1B | -786 |
| SHOC2 | -749 |
| PSMB5 | -742 |
| AP1S3 | -739 |
| SFTPB | -720 |
| RPL13 | -706 |
| MAPK8 | -700 |
| ITGA2B | -688 |
| C1QBP | -682 |
| ADCY2 | -667 |
| CALM1 | -655 |
| BAIAP2 | -637 |
| POLR2J | -603 |
| GCC2 | -597 |
| REST | -593 |
| ERCC2 | -583 |
| TRAF2 | -577 |
| NCSTN | -554 |
| PRKX | -553 |
| SKP1 | -544 |
| ATIC | -520 |
| UNC93B1 | -517 |
| JAG2 | -516 |
| RPL5 | -495 |
| TAF9 | -483 |
| CD19 | -472 |
| SLC29A3 | -456 |
| PSMD11 | -432 |
| TAF11 | -429 |
| ALG9 | -426 |
| GTF2H4 | -406 |
| CAST | -381 |
| CYP17A1 | -380 |
| TRAF3 | -356 |
| HDAC2 | -338 |
| NUP160 | -329 |
| NUP62 | -299 |
| DUSP9 | -284 |
| MPRIP | -266 |
| B4GALT1 | -262 |
| MSH3 | -255 |
| GGT1 | -250 |
| RPL22L1 | -214 |
| TAF2 | -206 |
| MNAT1 | -205 |
| CDC26 | -197 |
| RPS3A | -179 |
| CDK5R1 | -157 |
| ARID4A | -156 |
| RPS27 | -152 |
| CCND1 | -137 |
| PSMA6 | -126 |
| CTBP1 | -41 |
| TPM3 | -40 |
| RANBP2 | -4 |
| KSR1 | -1 |
| PRKAR1A | 4 |
| NOXO1 | 10 |
| AP3B1 | 13 |
| NELFE | 26 |
| EML4 | 27 |
| XRCC6 | 28 |
| HDAC3 | 38 |
| CSF2RA | 43 |
| RAC1 | 44 |
| STAT2 | 76 |
| SLC26A3 | 83 |
| KITLG | 92 |
| DOLK | 108 |
| ACACA | 118 |
| YWHAE | 129 |
| HDAC7 | 130 |
| ABCA4 | 138 |
| SLC4A1 | 141 |
| FMO3 | 142 |
| SDC2 | 147 |
| ENTPD1 | 184 |
| FZR1 | 201 |
| KPNA5 | 258 |
| RPL9 | 261 |
| SLC22A18 | 262 |
| PPP2R5E | 283 |
| FDX2 | 285 |
| ANAPC4 | 305 |
| RAP1A | 309 |
| PORCN | 320 |
| GTF2A1 | 328 |
| RPL31 | 330 |
| FGF5 | 342 |
| SUZ12 | 346 |
| KREMEN1 | 364 |
| FEN1 | 367 |
| PDPK1 | 399 |
| ATP1A4 | 412 |
| PACS1 | 414 |
| RPS26 | 419 |
| PSMB10 | 423 |
| E2F3 | 444 |
| MSH6 | 450 |
| GNAS | 459 |
| PARP4 | 462 |
| RB1 | 470 |
| CREB1 | 474 |
| ARID4B | 480 |
| WDR48 | 543 |
| PRELP | 546 |
| TPR | 565 |
| APH1A | 619 |
| TAF10 | 626 |
| F2 | 635 |
| ELOC | 645 |
| SLC6A14 | 695 |
| GNB5 | 700 |
| F8 | 735 |
| C1GALT1 | 742 |
| SIGMAR1 | 753 |
| UBC | 779 |
| TAF1 | 788 |
| VPS37D | 809 |
| CUBN | 854 |
| SLC6A20 | 876 |
| CHMP4A | 909 |
| AP1M2 | 914 |
| AP1B1 | 940 |
| ELMO2 | 942 |
| GPC4 | 952 |
| TCF7L2 | 959 |
| GPR39 | 994 |
| IFNGR2 | 997 |
| HDAC11 | 1004 |
| GYG2 | 1023 |
| PML | 1051 |
| PSMB1 | 1054 |
| G6PC3 | 1108 |
| ALG8 | 1117 |
| TLR6 | 1131 |
| PIK3R4 | 1132 |
| TAF6 | 1145 |
| CDC16 | 1175 |
| RNF43 | 1197 |
| BRAP | 1211 |
| CHMP3 | 1229 |
| MTRR | 1240 |
| ADAMTS4 | 1241 |
| EPS15 | 1254 |
| GUSB | 1260 |
| RANBP1 | 1308 |
| ALG13 | 1348 |
| GPR83 | 1350 |
| KLKB1 | 1361 |
| NUP133 | 1362 |
| MLH1 | 1370 |
| RPL21 | 1385 |
| BTRC | 1386 |
| TBL1XR1 | 1404 |
| ZFYVE9 | 1407 |
| ACTR2 | 1435 |
| TMPRSS2 | 1456 |
| SGSH | 1472 |
| ATM | 1503 |
| NCK1 | 1525 |
| PAPSS2 | 1548 |
| STRA6 | 1551 |
| GLB1 | 1557 |
| CPSF4 | 1570 |
| GAB1 | 1575 |
| KAT5 | 1580 |
| IRAK4 | 1591 |
| IFNGR1 | 1624 |
| NF1 | 1648 |
| MIB1 | 1650 |
| VTA1 | 1653 |
| SUGT1 | 1662 |
| CAMK2D | 1711 |
| MGAT4C | 1714 |
| PRKACA | 1736 |
| PCCB | 1766 |
| MTA1 | 1810 |
| HSPA1A | 1835 |
| STX1B | 1841 |
| MLST8 | 1875 |
| PSMB2 | 1876 |
| FADD | 1889 |
| MYC | 1892 |
| NMT2 | 1894 |
| VWF | 1933 |
| GNB4 | 1936 |
| FYN | 1937 |
| CYFIP1 | 1939 |
| MMAA | 1953 |
| ALDOB | 1990 |
| ANAPC1 | 1998 |
| POLR2G | 2003 |
| ABL1 | 2023 |
| AP2B1 | 2029 |
| AGK | 2062 |
| YWHAB | 2082 |
| SLC7A9 | 2093 |
| FGF23 | 2097 |
| IL18 | 2102 |
| FRS3 | 2112 |
| DNMT1 | 2134 |
| RPL22 | 2142 |
| CAMK2G | 2145 |
| SDC1 | 2160 |
| CYBA | 2202 |
| GCLM | 2237 |
| ITPR2 | 2257 |
| FZD8 | 2263 |
| MAPK14 | 2269 |
| FOXO3 | 2282 |
| NRAS | 2310 |
| EED | 2369 |
| VPS4A | 2374 |
| NUP58 | 2380 |
| DHDDS | 2399 |
| CYP24A1 | 2409 |
| POLR2D | 2418 |
| FDX1 | 2458 |
| MEFV | 2468 |
| VPS36 | 2474 |
| CYSLTR1 | 2493 |
| DYNLL1 | 2509 |
| PLCG1 | 2511 |
| THBS2 | 2512 |
| GALE | 2553 |
| ATRX | 2556 |
| SLC26A2 | 2580 |
| LRAT | 2585 |
| COMT | 2597 |
| HYAL1 | 2604 |
| WASF3 | 2619 |
| CDK9 | 2631 |
| UGT1A1 | 2676 |
| CHMP7 | 2690 |
| CHST3 | 2703 |
| POLR2A | 2705 |
| NUP153 | 2712 |
| SMAD4 | 2742 |
| PPP2R5C | 2743 |
| CCNE1 | 2754 |
| ZMYM2 | 2755 |
| ACE2 | 2757 |
| NUP43 | 2808 |
| GANAB | 2813 |
| VAV2 | 2817 |
| RPL36A | 2875 |
| ADAMTS7 | 2880 |
| EIF2AK2 | 2886 |
| SLC24A4 | 2892 |
| VPS25 | 2895 |
| AP1M1 | 2926 |
| ABCG8 | 2955 |
| ADAMTSL3 | 2956 |
| AAAS | 2965 |
| SV2A | 2966 |
| SLC7A7 | 2968 |
| PARP1 | 2974 |
| SRPK1 | 3007 |
| ARPC1A | 3022 |
| WRN | 3032 |
| ABCA3 | 3033 |
| FDXR | 3064 |
| STAM2 | 3080 |
| RPIA | 3101 |
| AGGF1 | 3135 |
| ABCC9 | 3136 |
| TCN2 | 3151 |
| CASP8 | 3157 |
| GSS | 3160 |
| CLCN6 | 3165 |
| SUPT16H | 3202 |
| ERLIN1 | 3212 |
| POMGNT1 | 3215 |
| DPM3 | 3217 |
| PARP8 | 3263 |
| CTNNB1 | 3272 |
| SUMO1 | 3308 |
| NUP54 | 3310 |
| ESR2 | 3316 |
| CORO1A | 3359 |
| DNMT3A | 3360 |
| XRCC4 | 3376 |
| DNA2 | 3379 |
| RANGAP1 | 3458 |
| EREG | 3467 |
| VAMP1 | 3484 |
| CYP2R1 | 3494 |
| IRS1 | 3502 |
| NTHL1 | 3521 |
| UBE2D1 | 3523 |
| SLC5A2 | 3524 |
| DOCK1 | 3540 |
| GIPR | 3556 |
| RAP1B | 3577 |
| SLC35D1 | 3595 |
| RMI1 | 3620 |
| DAXX | 3635 |
| TRAK1 | 3646 |
| CNKSR1 | 3649 |
| NR4A1 | 3691 |
| CDKN2A | 3704 |
| MPDU1 | 3718 |
| UBE2E1 | 3733 |
| PTGES3 | 3734 |
| PAPSS1 | 3746 |
| ADAMTS1 | 3770 |
| NEURL1B | 3778 |
| BANF1 | 3790 |
| ARPC3 | 3797 |
| GYS1 | 3798 |
| RBBP8 | 3824 |
| HDAC8 | 3835 |
| TRADD | 3885 |
| PMS2 | 3890 |
| MYO18A | 3903 |
| SLC35A1 | 3906 |
| OGG1 | 3917 |
| ANAPC5 | 3942 |
| ENTPD5 | 3958 |
| SRC | 3962 |
| TBP | 3968 |
| BAG4 | 4019 |
| VPS33B | 4043 |
| SLC16A1 | 4057 |
| MSH2 | 4066 |
| HHAT | 4068 |
| B4GALT7 | 4091 |
| MRE11 | 4100 |
| CDK2 | 4114 |
| CCNT2 | 4117 |
| GNG5 | 4123 |
| VPS28 | 4152 |
| RAD51B | 4156 |
| IFNAR1 | 4161 |
| NUP85 | 4178 |
| GPC3 | 4191 |
| CAMK4 | 4196 |
| KDM1A | 4224 |
| SDC3 | 4241 |
| ERBB3 | 4249 |
| STAT3 | 4253 |
| SLC2A10 | 4273 |
| ACY1 | 4275 |
| ABCC6 | 4285 |
| ADCY9 | 4287 |
| NOTCH3 | 4292 |
| PSMD12 | 4303 |
| PALB2 | 4305 |
| GPC6 | 4318 |
| CYP21A2 | 4343 |
| SLCO1B3 | 4370 |
| GTF2H5 | 4373 |
| RAE1 | 4394 |
| VCL | 4407 |
| DKK1 | 4410 |
| ZC3HAV1 | 4414 |
| GNG7 | 4426 |
| RNMT | 4440 |
| TIRAP | 4446 |
| KCNJ11 | 4499 |
| ANTXR1 | 4532 |
| NBN | 4533 |
| GTF2F2 | 4556 |
| CAMK2A | 4566 |
| PSMD4 | 4567 |
| HMOX1 | 4592 |
| POLR2I | 4594 |
| DRD5 | 4609 |
| KLC1 | 4611 |
| PPP2R1B | 4614 |
| CBX1 | 4668 |
| GAA | 4697 |
| ZCRB1 | 4731 |
| CDK6 | 4754 |
| SRD5A3 | 4758 |
| TBXAS1 | 4766 |
| RBPJ | 4794 |
| NUP155 | 4796 |
| ADCY1 | 4808 |
| MUC15 | 4828 |
| F11 | 4836 |
| KANK1 | 4837 |
| FZD5 | 4841 |
| TFDP2 | 4856 |
| AHCYL1 | 4874 |
| DUSP8 | 4879 |
| MMACHC | 4886 |
| IMPDH2 | 4910 |
| PSMD10 | 4933 |
| PSMD7 | 4942 |
| ALG6 | 4943 |
| POLA1 | 4949 |
| SLC35A3 | 4972 |
| SLCO2A1 | 4980 |
| EPM2A | 5000 |
| AMER1 | 5007 |
| ADAMTS13 | 5043 |
| TYK2 | 5066 |
| MPI | 5076 |
| KAT2A | 5077 |
| RFT1 | 5083 |
| BGN | 5087 |
| BRCA1 | 5107 |
| STAM | 5109 |
| AKAP9 | 5113 |
| PSMD5 | 5116 |
| MRAS | 5118 |
| TUBB | 5125 |
| ADORA2B | 5127 |
| RBBP7 | 5134 |
| GPC1 | 5178 |
| CHST6 | 5182 |
| SLC24A1 | 5215 |
| ABCD4 | 5258 |
| CD36 | 5264 |
| STAT5A | 5288 |
| GPR176 | 5289 |
| OPLAH | 5314 |
| RDH5 | 5315 |
| GTF2H2 | 5321 |
| ADORA2A | 5330 |
| H2AFX | 5356 |
| PARP14 | 5386 |
| BRCA2 | 5396 |
| P2RX4 | 5401 |
| ERLIN2 | 5405 |
| GSDMD | 5413 |
| FOXO1 | 5418 |
| MMADHC | 5435 |
| GTF2A2 | 5445 |
| ATG7 | 5453 |
| NCKIPSD | 5477 |
| FZD7 | 5487 |
| PSMB9 | 5491 |
| NOXA1 | 5500 |
| GTF2E1 | 5502 |
| ERBB2 | 5534 |
| HMGB1 | 5546 |
| CCNH | 5556 |
| SLC37A4 | 5575 |
| EXT2 | 5580 |
| RNF213 | 5584 |
| MVB12A | 5589 |
| CYP11A1 | 5667 |
| F10 | 5732 |
| RDH12 | 5744 |
| HLA-A | 5777 |
| ZC3HC1 | 5790 |
| AGTRAP | 5793 |
| AP1S1 | 5804 |
| IDUA | 5809 |
| GPC2 | 5828 |
| NUP93 | 5831 |
| PARP10 | 5859 |
| CHMP6 | 5904 |
| ST3GAL3 | 5918 |
| HGSNAT | 5921 |
| MYD88 | 5939 |
| SKP2 | 5946 |
| PSTPIP1 | 5948 |
| HDAC6 | 5953 |
| CDC25A | 5954 |
| POLR2K | 5962 |
| PSMD14 | 5974 |
| NUP35 | 5982 |
| THBS1 | 5988 |
| CYP2U1 | 5991 |
| BLM | 5994 |
| FLT3LG | 6000 |
| GTF2H3 | 6024 |
| RAD51C | 6033 |
| DYNLL2 | 6044 |
| GNE | 6051 |
| MTR | 6057 |
| ANAPC10 | 6071 |
| CD4 | 6074 |
| NUP107 | 6076 |
| TAF9B | 6106 |
| CASP1 | 6109 |
| CDC23 | 6113 |
| MAT1A | 6114 |
| BARD1 | 6138 |
| RAD51D | 6153 |
| GNG4 | 6164 |
| APH1B | 6168 |
| LIG1 | 6206 |
| CYFIP2 | 6224 |
| NEIL3 | 6230 |
| NOTCH2 | 6231 |
| ANAPC7 | 6249 |
| CDC25B | 6275 |
| KHK | 6286 |
| RAMP2 | 6288 |
| ANAPC16 | 6307 |
| FZD6 | 6312 |
| ADCY7 | 6316 |
| RAD51 | 6326 |
| FAM114A2 | 6340 |
| GALT | 6341 |
| NEIL1 | 6345 |
| CNTRL | 6358 |
| BRIP1 | 6392 |
| F12 | 6397 |
| ADAMTS9 | 6402 |
| MTA3 | 6411 |
| E2F2 | 6426 |
| CYP19A1 | 6444 |
| LIG4 | 6454 |
| CHST14 | 6461 |
| ADAMTS6 | 6501 |
| IL1R1 | 6510 |
| XRCC2 | 6513 |
| FZD4 | 6534 |
| MUTYH | 6556 |
| STAT5B | 6572 |
| PRIM2 | 6599 |
| TAF12 | 6601 |
| ABCG5 | 6607 |
| DUT | 6636 |
| WDCP | 6637 |
| MAPK3 | 6640 |
| EXO1 | 6663 |
| PPP1R3C | 6692 |
| POLA2 | 6695 |
| FGG | 6697 |
| GNG10 | 6779 |
| SLC39A4 | 6798 |
| NUP210 | 6802 |
| FGFR2 | 6811 |
| NCBP2 | 6823 |
| CDC25C | 6825 |
| MAML2 | 6847 |
| S100A1 | 6858 |
| CEBPD | 6867 |
| PYCARD | 6900 |
| PDGFB | 6920 |
| ADAMTS2 | 6939 |
| DNMT3B | 6957 |
| PRIM1 | 6962 |
| ADAMTS10 | 6971 |
| PARP9 | 6988 |
| APOA1 | 6993 |
| CD14 | 6998 |
| ADAMTSL4 | 7040 |
| TAF15 | 7061 |
| APOBEC3G | 7066 |
| MC1R | 7078 |
| E2F1 | 7096 |
| NUP37 | 7100 |
| LMNB1 | 7101 |
| CTNND1 | 7129 |
| UBE2C | 7137 |
| HSPG2 | 7157 |
| GALK1 | 7177 |
| PSIP1 | 7193 |
| MMAB | 7195 |
| RMI2 | 7209 |
| FGB | 7226 |
| NEDD4L | 7233 |
| RAD51AP1 | 7241 |
| SLC2A2 | 7259 |
| HES1 | 7265 |
| GCKR | 7281 |
| CDH1 | 7296 |
| RBP4 | 7308 |
| HIP1 | 7319 |
| CP | 7325 |
| JAK3 | 7326 |
| FGA | 7336 |
| SOD2 | 7342 |
| C3 | 7357 |
| MUC5B | 7378 |
| TXNIP | 7384 |
| SERPING1 | 7387 |
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
| 721 | |
|---|---|
| set | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
| setSize | 111 |
| pANOVA | 3.73e-11 |
| s.dist | -0.364 |
| p.adjustANOVA | 1.83e-09 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| ETF1 | -6952 |
| RNPS1 | -6938 |
| GSPT1 | -6825 |
| UPF3A | -6189 |
| CASC3 | -5986 |
| EIF4G1 | -5901 |
| RPL19 | -5254 |
| PPP2CA | -5168 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| PPP2R1A | -4744 |
| RPS11 | -4702 |
| UPF1 | -4700 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| ETF1 | -6952 |
| RNPS1 | -6938 |
| GSPT1 | -6825 |
| UPF3A | -6189 |
| CASC3 | -5986 |
| EIF4G1 | -5901 |
| RPL19 | -5254 |
| PPP2CA | -5168 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| PPP2R1A | -4744 |
| RPS11 | -4702 |
| UPF1 | -4700 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| RPL30 | -4081 |
| RPS9 | -4028 |
| RPL18 | -3961 |
| RPL26L1 | -3873 |
| SMG8 | -3868 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| UPF2 | -3830 |
| RPL28 | -3546 |
| PABPC1 | -3543 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| RPS15A | -3019 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| SMG1 | -2778 |
| RPS27A | -2773 |
| SMG7 | -2718 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| NCBP1 | -2151 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| RPL23 | -1913 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| RBM8A | -1583 |
| SMG6 | -1323 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| MAGOH | -969 |
| RPS25 | -937 |
| RPL13 | -706 |
| SMG5 | -654 |
| RPL5 | -495 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| DCP1A | 40 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPS26 | 419 |
| EIF4A3 | 1154 |
| RPL21 | 1385 |
| RPL22 | 2142 |
| UPF3B | 2326 |
| RPL36A | 2875 |
| SMG9 | 3998 |
| PNRC2 | 5595 |
| PPP2R2A | 5688 |
| MAGOHB | 5814 |
| NCBP2 | 6823 |
Nonsense-Mediated Decay (NMD)
| 723 | |
|---|---|
| set | Nonsense-Mediated Decay (NMD) |
| setSize | 111 |
| pANOVA | 3.73e-11 |
| s.dist | -0.364 |
| p.adjustANOVA | 1.83e-09 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| ETF1 | -6952 |
| RNPS1 | -6938 |
| GSPT1 | -6825 |
| UPF3A | -6189 |
| CASC3 | -5986 |
| EIF4G1 | -5901 |
| RPL19 | -5254 |
| PPP2CA | -5168 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| PPP2R1A | -4744 |
| RPS11 | -4702 |
| UPF1 | -4700 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| ETF1 | -6952 |
| RNPS1 | -6938 |
| GSPT1 | -6825 |
| UPF3A | -6189 |
| CASC3 | -5986 |
| EIF4G1 | -5901 |
| RPL19 | -5254 |
| PPP2CA | -5168 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| PPP2R1A | -4744 |
| RPS11 | -4702 |
| UPF1 | -4700 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| RPL30 | -4081 |
| RPS9 | -4028 |
| RPL18 | -3961 |
| RPL26L1 | -3873 |
| SMG8 | -3868 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| UPF2 | -3830 |
| RPL28 | -3546 |
| PABPC1 | -3543 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| RPS15A | -3019 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| SMG1 | -2778 |
| RPS27A | -2773 |
| SMG7 | -2718 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| NCBP1 | -2151 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| RPL23 | -1913 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| RBM8A | -1583 |
| SMG6 | -1323 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| MAGOH | -969 |
| RPS25 | -937 |
| RPL13 | -706 |
| SMG5 | -654 |
| RPL5 | -495 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| DCP1A | 40 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPS26 | 419 |
| EIF4A3 | 1154 |
| RPL21 | 1385 |
| RPL22 | 2142 |
| UPF3B | 2326 |
| RPL36A | 2875 |
| SMG9 | 3998 |
| PNRC2 | 5595 |
| PPP2R2A | 5688 |
| MAGOHB | 5814 |
| NCBP2 | 6823 |
Viral mRNA Translation
| 1330 | |
|---|---|
| set | Viral mRNA Translation |
| setSize | 86 |
| pANOVA | 5.18e-11 |
| s.dist | -0.41 |
| p.adjustANOVA | 2.46e-09 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| DNAJC3 | -7131 |
| RPL36AL | -6981 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| GRSF1 | -4747 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| DNAJC3 | -7131 |
| RPL36AL | -6981 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| GRSF1 | -4747 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| RPL30 | -4081 |
| RPS9 | -4028 |
| RPL18 | -3961 |
| RPL26L1 | -3873 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| RPL28 | -3546 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| RPS15A | -3019 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| RPS27A | -2773 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| RPL23 | -1913 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| RPS25 | -937 |
| RPL13 | -706 |
| RPL5 | -495 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPS26 | 419 |
| RPL21 | 1385 |
| RPL22 | 2142 |
| RPL36A | 2875 |
Influenza Infection
| 511 | |
|---|---|
| set | Influenza Infection |
| setSize | 151 |
| pANOVA | 6.29e-11 |
| s.dist | -0.309 |
| p.adjustANOVA | 2.89e-09 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CALR | -7142 |
| DNAJC3 | -7131 |
| CANX | -7092 |
| RPL36AL | -6981 |
| TGFB1 | -6934 |
| SEC13 | -6812 |
| KPNA1 | -6701 |
| RAN | -6476 |
| CLTA | -6439 |
| KPNB1 | -6379 |
| IPO5 | -6366 |
| POM121 | -6353 |
| CLTC | -6220 |
| POM121C | -6045 |
| ISG15 | -5488 |
| POLR2L | -5471 |
| POLR2F | -5283 |
| NUP205 | -5275 |
| RPL19 | -5254 |
| RPS7 | -5138 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CALR | -7142 |
| DNAJC3 | -7131 |
| CANX | -7092 |
| RPL36AL | -6981 |
| TGFB1 | -6934 |
| SEC13 | -6812 |
| KPNA1 | -6701 |
| RAN | -6476 |
| CLTA | -6439 |
| KPNB1 | -6379 |
| IPO5 | -6366 |
| POM121 | -6353 |
| CLTC | -6220 |
| POM121C | -6045 |
| ISG15 | -5488 |
| POLR2L | -5471 |
| POLR2F | -5283 |
| NUP205 | -5275 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| NUP188 | -4991 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| NUP88 | -4777 |
| GRSF1 | -4747 |
| NUP50 | -4733 |
| RPS11 | -4702 |
| POLR2E | -4667 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| KPNA2 | -4575 |
| SEH1L | -4472 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| KPNA3 | -4357 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| RPL30 | -4081 |
| RPS9 | -4028 |
| RPL18 | -3961 |
| RPL26L1 | -3873 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| NUP98 | -3764 |
| SLC25A6 | -3733 |
| POLR2B | -3699 |
| POLR2H | -3593 |
| RPL28 | -3546 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| POLR2C | -3425 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| GTF2F1 | -3103 |
| RPS15A | -3019 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| RPS27A | -2773 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| PABPN1 | -2037 |
| NUP214 | -1926 |
| RPL23 | -1913 |
| XPO1 | -1864 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| KPNA4 | -1701 |
| NDC1 | -1490 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| HSP90AA1 | -1030 |
| RPL12 | -983 |
| RPS25 | -937 |
| RPL13 | -706 |
| POLR2J | -603 |
| RPL5 | -495 |
| NUP160 | -329 |
| NUP62 | -299 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| RANBP2 | -4 |
| KPNA5 | 258 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPS26 | 419 |
| TPR | 565 |
| NUP133 | 1362 |
| RPL21 | 1385 |
| CPSF4 | 1570 |
| HSPA1A | 1835 |
| POLR2G | 2003 |
| RPL22 | 2142 |
| NUP58 | 2380 |
| POLR2D | 2418 |
| POLR2A | 2705 |
| NUP153 | 2712 |
| NUP43 | 2808 |
| RPL36A | 2875 |
| EIF2AK2 | 2886 |
| AAAS | 2965 |
| PARP1 | 2974 |
| NUP54 | 3310 |
| NUP85 | 4178 |
| RAE1 | 4394 |
| GTF2F2 | 4556 |
| POLR2I | 4594 |
| NUP155 | 4796 |
| NUP93 | 5831 |
| POLR2K | 5962 |
| NUP35 | 5982 |
| NUP107 | 6076 |
| NUP210 | 6802 |
| NUP37 | 7100 |
rRNA processing in the nucleus and cytosol
| 1370 | |
|---|---|
| set | rRNA processing in the nucleus and cytosol |
| setSize | 184 |
| pANOVA | 7.82e-11 |
| s.dist | -0.278 |
| p.adjustANOVA | 3.47e-09 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| MPHOSPH10 | -6827 |
| DDX49 | -6809 |
| EXOSC6 | -6503 |
| RRP36 | -6354 |
| RIOK3 | -6332 |
| UTP14C | -6243 |
| UTP4 | -6111 |
| UTP14A | -5799 |
| PNO1 | -5758 |
| CSNK1D | -5722 |
| LTV1 | -5474 |
| GNL3 | -5332 |
| RPL19 | -5254 |
| DHX37 | -5250 |
| NOP14 | -5209 |
| RPS7 | -5138 |
| RRP1 | -5133 |
| UBA52 | -5068 |
| RPL11 | -5032 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| MPHOSPH10 | -6827 |
| DDX49 | -6809 |
| EXOSC6 | -6503 |
| RRP36 | -6354 |
| RIOK3 | -6332 |
| UTP14C | -6243 |
| UTP4 | -6111 |
| UTP14A | -5799 |
| PNO1 | -5758 |
| CSNK1D | -5722 |
| LTV1 | -5474 |
| GNL3 | -5332 |
| RPL19 | -5254 |
| DHX37 | -5250 |
| NOP14 | -5209 |
| RPS7 | -5138 |
| RRP1 | -5133 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| NOP10 | -4958 |
| NOL9 | -4954 |
| IMP4 | -4940 |
| RPS5 | -4778 |
| BMS1 | -4769 |
| EXOSC5 | -4766 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| IMP3 | -4633 |
| UTP18 | -4476 |
| RPLP1 | -4391 |
| BOP1 | -4381 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| TEX10 | -4283 |
| NHP2 | -4261 |
| WDR43 | -4193 |
| RPL35A | -4159 |
| RPL30 | -4081 |
| DDX47 | -4068 |
| RPS9 | -4028 |
| RIOK2 | -4018 |
| RPL18 | -3961 |
| DDX52 | -3894 |
| RPL26L1 | -3873 |
| TRMT112 | -3869 |
| NOP2 | -3859 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| NOL12 | -3773 |
| NOB1 | -3772 |
| ISG20L2 | -3623 |
| EBNA1BP2 | -3613 |
| RPL28 | -3546 |
| RPSA | -3520 |
| PES1 | -3505 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| EXOSC3 | -3453 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| XRN2 | -3427 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| RPS15A | -3019 |
| GAR1 | -3015 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| PELP1 | -2894 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| UTP20 | -2811 |
| RPS27A | -2773 |
| FCF1 | -2713 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| BYSL | -2637 |
| RPL41 | -2635 |
| RRP9 | -2591 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| UTP15 | -2509 |
| ERI1 | -2490 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| NIP7 | -2165 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| PWP2 | -2005 |
| RPL23 | -1913 |
| NCL | -1840 |
| UTP6 | -1836 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| DIS3 | -1573 |
| NOC4L | -1552 |
| FBL | -1548 |
| SENP3 | -1399 |
| UTP11 | -1337 |
| HEATR1 | -1324 |
| RPL15 | -1313 |
| DKC1 | -1249 |
| RPL3 | -1165 |
| NOP56 | -1145 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| RCL1 | -942 |
| RPS25 | -937 |
| TSR1 | -851 |
| TBL3 | -794 |
| RPL13 | -706 |
| RPL5 | -495 |
| TSR3 | -466 |
| EXOSC10 | -341 |
| THUMPD1 | -270 |
| DDX21 | -256 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| SNU13 | -129 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPS26 | 419 |
| EXOSC8 | 472 |
| RBM28 | 771 |
| KRR1 | 924 |
| RPP14 | 1309 |
| RPL21 | 1385 |
| RPP30 | 1439 |
| RPP38 | 1564 |
| RPP40 | 1770 |
| NOL6 | 1999 |
| RRP7A | 2006 |
| FTSJ3 | 2052 |
| WDR18 | 2127 |
| RPL22 | 2142 |
| DIMT1 | 2382 |
| RIOK1 | 2711 |
| RPL36A | 2875 |
| EXOSC4 | 3220 |
| CSNK1E | 3247 |
| EXOSC9 | 3293 |
| PDCD11 | 3334 |
| NAT10 | 3342 |
| C1D | 3482 |
| EXOSC1 | 3486 |
| WDR75 | 3573 |
| EXOSC2 | 3779 |
| WDR12 | 3814 |
| NOL11 | 4020 |
| UTP3 | 4280 |
| DCAF13 | 4652 |
| WDR46 | 4709 |
| EXOSC7 | 5196 |
| NOP58 | 5612 |
| MPHOSPH6 | 5619 |
| WDR3 | 5692 |
| WDR36 | 5735 |
| LAS1L | 7022 |
| EMG1 | 7347 |
Peptide chain elongation
| 784 | |
|---|---|
| set | Peptide chain elongation |
| setSize | 86 |
| pANOVA | 8.24e-11 |
| s.dist | -0.405 |
| p.adjustANOVA | 3.55e-09 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| EEF2 | -5049 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| EEF1A1 | -4138 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| EEF2 | -5049 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| EEF1A1 | -4138 |
| RPL30 | -4081 |
| RPS9 | -4028 |
| RPL18 | -3961 |
| RPL26L1 | -3873 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| RPL28 | -3546 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| RPS15A | -3019 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| RPS27A | -2773 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| RPL23 | -1913 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| RPS25 | -937 |
| RPL13 | -706 |
| RPL5 | -495 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPS26 | 419 |
| RPL21 | 1385 |
| RPL22 | 2142 |
| RPL36A | 2875 |
Immune System
| 502 | |
|---|---|
| set | Immune System |
| setSize | 1374 |
| pANOVA | 8.91e-11 |
| s.dist | -0.106 |
| p.adjustANOVA | 3.72e-09 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| HSPA5 | -7144 |
| CALR | -7142 |
| SEC24D | -7134 |
| DNAJC3 | -7131 |
| HSP90B1 | -7129 |
| CANX | -7092 |
| PDIA3 | -7086 |
| VASP | -7075 |
| PLPP5 | -7074 |
| KLHL21 | -7069 |
| UBE2J1 | -7068 |
| ATP6V0B | -7064 |
| MAP3K8 | -7060 |
| NCR3LG1 | -7048 |
| MAGT1 | -7045 |
| CNN2 | -7036 |
| SEC61A1 | -7030 |
| ERP44 | -7023 |
| SQSTM1 | -7010 |
| EIF4A1 | -6995 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HSPA5 | -7144 |
| CALR | -7142 |
| SEC24D | -7134 |
| DNAJC3 | -7131 |
| HSP90B1 | -7129 |
| CANX | -7092 |
| PDIA3 | -7086 |
| VASP | -7075 |
| PLPP5 | -7074 |
| KLHL21 | -7069 |
| UBE2J1 | -7068 |
| ATP6V0B | -7064 |
| MAP3K8 | -7060 |
| NCR3LG1 | -7048 |
| MAGT1 | -7045 |
| CNN2 | -7036 |
| SEC61A1 | -7030 |
| ERP44 | -7023 |
| SQSTM1 | -7010 |
| EIF4A1 | -6995 |
| SNRPA1 | -6983 |
| LAMP1 | -6982 |
| ATP6V0A1 | -6979 |
| CEACAM1 | -6974 |
| LAMP2 | -6966 |
| ASB2 | -6960 |
| STX3 | -6959 |
| SEC61B | -6958 |
| PIK3AP1 | -6957 |
| OAS1 | -6953 |
| CTSL | -6951 |
| ARSB | -6939 |
| IL17RB | -6937 |
| GGH | -6936 |
| TGFB1 | -6934 |
| CCR6 | -6932 |
| LGALS3 | -6923 |
| ATP6V1D | -6922 |
| SHC1 | -6910 |
| ATP6V0D1 | -6908 |
| MLEC | -6902 |
| CCL20 | -6885 |
| P4HB | -6884 |
| ATP6V0A2 | -6880 |
| S100A11 | -6865 |
| P2RX1 | -6853 |
| BRI3 | -6843 |
| ACTG1 | -6841 |
| SEC24A | -6839 |
| FLNA | -6833 |
| GNS | -6813 |
| SEC13 | -6812 |
| PNP | -6810 |
| NDUFC2 | -6804 |
| TRIB3 | -6798 |
| C4BPB | -6787 |
| CYSTM1 | -6768 |
| BTN2A1 | -6754 |
| NEU1 | -6752 |
| NFATC3 | -6750 |
| HNRNPF | -6735 |
| VCP | -6720 |
| IRAK2 | -6713 |
| CSF1 | -6711 |
| KPNA1 | -6701 |
| FTL | -6697 |
| PYGB | -6693 |
| SIAH2 | -6666 |
| PSMF1 | -6663 |
| ASAH1 | -6648 |
| SOCS5 | -6643 |
| UBE2Q1 | -6639 |
| KIF5A | -6634 |
| ATP6V0E1 | -6622 |
| SURF4 | -6593 |
| RAPGEF1 | -6586 |
| HSPA9 | -6580 |
| TOLLIP | -6576 |
| NF2 | -6559 |
| RALA | -6548 |
| WASL | -6543 |
| DUSP3 | -6541 |
| IGF2R | -6540 |
| FUCA2 | -6538 |
| DNM2 | -6535 |
| DNAJC5 | -6522 |
| CD55 | -6517 |
| TMBIM1 | -6493 |
| APP | -6492 |
| VHL | -6491 |
| TRIM5 | -6483 |
| KEAP1 | -6482 |
| NFKBIB | -6474 |
| EP300 | -6470 |
| ALDOA | -6463 |
| MAPKAPK2 | -6461 |
| HEXB | -6455 |
| CLEC10A | -6451 |
| PSME4 | -6450 |
| DDX3X | -6449 |
| HNRNPA2B1 | -6445 |
| ICAM3 | -6441 |
| CLTA | -6439 |
| NFKBIA | -6437 |
| PSMD2 | -6435 |
| DDOST | -6429 |
| EIF4G2 | -6418 |
| CDK13 | -6415 |
| KCMF1 | -6393 |
| KPNB1 | -6379 |
| PJA2 | -6376 |
| ARIH2 | -6355 |
| POM121 | -6353 |
| BCL2L1 | -6349 |
| UBR4 | -6345 |
| ATAD3B | -6334 |
| UBE2O | -6331 |
| KIF3B | -6315 |
| GALNS | -6314 |
| TIMP1 | -6294 |
| CTSA | -6288 |
| TAX1BP1 | -6281 |
| ATP6V1E1 | -6271 |
| PRDX4 | -6268 |
| CD22 | -6256 |
| LCK | -6250 |
| RBBP6 | -6244 |
| SEC24C | -6236 |
| UBE2J2 | -6232 |
| MAP3K1 | -6230 |
| SMURF1 | -6229 |
| CLTC | -6220 |
| SH3RF1 | -6212 |
| NPC2 | -6207 |
| IFI30 | -6187 |
| ATF2 | -6175 |
| PGAM1 | -6174 |
| RAP2B | -6173 |
| SMAD3 | -6145 |
| TRIM26 | -6126 |
| TMC6 | -6114 |
| CD63 | -6107 |
| PTPRJ | -6103 |
| PDXK | -6100 |
| ARPC4 | -6094 |
| IRF9 | -6092 |
| ITCH | -6089 |
| ITPR3 | -6088 |
| ATP6V0C | -6086 |
| CYLD | -6066 |
| MASP1 | -6062 |
| DEGS1 | -6054 |
| OAS3 | -6048 |
| MYLIP | -6047 |
| POM121C | -6045 |
| UBE3C | -6041 |
| TPP2 | -6027 |
| MALT1 | -6026 |
| ARF1 | -6021 |
| COLEC11 | -5996 |
| DUSP4 | -5977 |
| PSMD6 | -5951 |
| IKBKG | -5946 |
| FBXW5 | -5945 |
| OTUD5 | -5944 |
| SRP14 | -5938 |
| MAPKAP1 | -5936 |
| MVP | -5935 |
| PRKCSH | -5934 |
| PTPN23 | -5932 |
| ATP6V1C2 | -5929 |
| CCT2 | -5926 |
| BPIFB6 | -5923 |
| ARL8A | -5922 |
| MYO9B | -5920 |
| DDX41 | -5919 |
| RNF130 | -5910 |
| EIF4G1 | -5901 |
| UBE2F | -5885 |
| THOP1 | -5882 |
| DOK3 | -5877 |
| RORA | -5875 |
| EIF4G3 | -5852 |
| CAPN1 | -5850 |
| ECSIT | -5840 |
| ADAM17 | -5836 |
| ANO6 | -5826 |
| IFITM3 | -5819 |
| KIF2A | -5815 |
| RAB7A | -5810 |
| DIAPH1 | -5806 |
| PSMA2 | -5801 |
| PVR | -5786 |
| RIPK2 | -5779 |
| MAPKAPK3 | -5773 |
| SEC31A | -5766 |
| UBE2G1 | -5763 |
| PPP2R5A | -5740 |
| CFL1 | -5737 |
| ELK1 | -5733 |
| PSMA1 | -5730 |
| WASF1 | -5712 |
| CBL | -5708 |
| MKRN1 | -5695 |
| SNAP23 | -5681 |
| STAT1 | -5668 |
| IQGAP1 | -5663 |
| CRK | -5650 |
| GLA | -5640 |
| PRKCD | -5638 |
| PANX1 | -5636 |
| POLR3E | -5626 |
| CCT8 | -5605 |
| PITPNA | -5591 |
| ATP6V1B2 | -5574 |
| PSMC1 | -5564 |
| RAF1 | -5557 |
| CASP10 | -5555 |
| TALDO1 | -5554 |
| HECTD1 | -5553 |
| MAP3K3 | -5546 |
| HRAS | -5543 |
| MAPK12 | -5538 |
| PSMD3 | -5535 |
| ITGB5 | -5532 |
| CDC34 | -5516 |
| TRIM8 | -5512 |
| PRKCE | -5510 |
| GRB10 | -5504 |
| TRIM25 | -5492 |
| ISG15 | -5488 |
| FBXO31 | -5485 |
| PSME2 | -5481 |
| CD58 | -5480 |
| LRRFIP1 | -5477 |
| SEC24B | -5475 |
| POLR2L | -5471 |
| IDH1 | -5470 |
| SOCS6 | -5467 |
| IRS2 | -5461 |
| MEX3C | -5460 |
| NCF2 | -5438 |
| BRK1 | -5431 |
| CLCF1 | -5429 |
| KIF5B | -5426 |
| FTH1 | -5419 |
| SOS2 | -5417 |
| TNFRSF12A | -5405 |
| PPM1B | -5398 |
| TXNDC5 | -5385 |
| TRAF7 | -5369 |
| ATP6V1G1 | -5352 |
| PSMD1 | -5351 |
| PTPN12 | -5326 |
| IQGAP2 | -5323 |
| FBXO32 | -5299 |
| ACTR3 | -5296 |
| RHOA | -5294 |
| MYO10 | -5290 |
| POLR2F | -5283 |
| NUP205 | -5275 |
| ILF2 | -5258 |
| CASP3 | -5257 |
| SMURF2 | -5253 |
| CASP9 | -5247 |
| ASB6 | -5243 |
| PELI1 | -5222 |
| PIK3C3 | -5220 |
| PSAP | -5218 |
| CTSB | -5204 |
| FKBP1A | -5189 |
| MIF | -5176 |
| FOS | -5174 |
| TBK1 | -5169 |
| PPP2CA | -5168 |
| ACTR1A | -5162 |
| ISG20 | -5154 |
| PKM | -5137 |
| PPP2R5B | -5131 |
| RNF6 | -5120 |
| VAMP2 | -5088 |
| AAMP | -5076 |
| UBA52 | -5068 |
| MAPK1 | -5066 |
| ACTB | -5057 |
| EEF2 | -5049 |
| ZAP70 | -5027 |
| RAP1GAP | -4998 |
| NUP188 | -4991 |
| POLR1C | -4986 |
| VAMP8 | -4969 |
| BPIFB2 | -4967 |
| TNFSF4 | -4966 |
| JAK1 | -4963 |
| PAK2 | -4957 |
| CAB39 | -4956 |
| ATP6V1C1 | -4946 |
| IL6R | -4943 |
| PSEN1 | -4938 |
| ATF1 | -4925 |
| GPI | -4904 |
| NOS3 | -4903 |
| VAPA | -4898 |
| PSMB6 | -4888 |
| WSB1 | -4879 |
| PSMC6 | -4878 |
| RAB31 | -4876 |
| KLHL42 | -4874 |
| CAPZA1 | -4855 |
| ORAI2 | -4848 |
| OSTF1 | -4843 |
| CTSK | -4821 |
| RNF19A | -4816 |
| PSMC4 | -4808 |
| NUP88 | -4777 |
| PIK3CD | -4759 |
| SH2B3 | -4752 |
| DSP | -4746 |
| SIPA1 | -4745 |
| PPP2R1A | -4744 |
| HMOX2 | -4742 |
| TCP1 | -4735 |
| NUP50 | -4733 |
| MYH9 | -4726 |
| PTEN | -4721 |
| FBXO44 | -4694 |
| GLIPR1 | -4691 |
| RNF123 | -4681 |
| MMP2 | -4677 |
| RILP | -4675 |
| POLR2E | -4667 |
| UBE2V1 | -4655 |
| HSPA8 | -4654 |
| VAV3 | -4642 |
| FAF2 | -4640 |
| PSMD9 | -4638 |
| TSPAN14 | -4626 |
| TANK | -4621 |
| AP2M1 | -4603 |
| PGM1 | -4600 |
| NKIRAS2 | -4598 |
| GBP2 | -4577 |
| KPNA2 | -4575 |
| OSCAR | -4571 |
| PPP2CB | -4523 |
| BATF | -4520 |
| POLR1D | -4516 |
| MAP2K4 | -4505 |
| TRIP12 | -4503 |
| RNF19B | -4500 |
| VAT1 | -4497 |
| ABI1 | -4478 |
| SEH1L | -4472 |
| BCL10 | -4471 |
| EIF4E2 | -4465 |
| VEGFA | -4456 |
| CTSC | -4446 |
| PPIA | -4443 |
| ARPC1B | -4429 |
| HSP90AB1 | -4426 |
| ATP6V1H | -4423 |
| MAP2K7 | -4399 |
| MAPK7 | -4382 |
| PIK3R1 | -4376 |
| PSMB7 | -4372 |
| KPNA3 | -4357 |
| MIB2 | -4356 |
| PTK2 | -4346 |
| IL18BP | -4340 |
| UBE2M | -4337 |
| ITPR1 | -4321 |
| ITGAV | -4312 |
| BCL6 | -4296 |
| RPLP0 | -4290 |
| AIP | -4270 |
| UBB | -4263 |
| TRIM4 | -4229 |
| PLEKHO2 | -4227 |
| RNF126 | -4225 |
| PSMA4 | -4211 |
| AP1S2 | -4204 |
| TOM1 | -4199 |
| ARG1 | -4179 |
| PPP3R1 | -4176 |
| YPEL5 | -4173 |
| ASB1 | -4171 |
| IFI6 | -4166 |
| HIF1A | -4165 |
| XRCC5 | -4164 |
| IP6K2 | -4148 |
| ITGB1 | -4145 |
| EEF1A1 | -4138 |
| CUL1 | -4129 |
| GAB2 | -4127 |
| MAP2K1 | -4120 |
| CSK | -4113 |
| DHX9 | -4112 |
| COPB1 | -4098 |
| LCN2 | -4096 |
| PIM1 | -4092 |
| PSMC5 | -4091 |
| CAP1 | -4085 |
| PTPN14 | -4062 |
| PPP3CB | -4060 |
| SEC61G | -4052 |
| UBE2D3 | -3997 |
| UBA5 | -3984 |
| CNPY3 | -3981 |
| NME2 | -3974 |
| ORM1 | -3973 |
| ADAR | -3971 |
| IL11 | -3967 |
| DCTN2 | -3957 |
| SARM1 | -3956 |
| FBXL20 | -3941 |
| CKAP4 | -3939 |
| TIMP2 | -3938 |
| TTR | -3924 |
| DYNC1LI2 | -3897 |
| ASB7 | -3889 |
| CREBBP | -3888 |
| TAB2 | -3878 |
| DUSP7 | -3870 |
| RPS6KA1 | -3857 |
| FBXO11 | -3853 |
| BCL2L11 | -3834 |
| ASB4 | -3822 |
| PSME3 | -3813 |
| PTPN2 | -3809 |
| FBXW11 | -3784 |
| ATP6V1A | -3777 |
| HUWE1 | -3769 |
| PLCG2 | -3766 |
| NUP98 | -3764 |
| LIFR | -3759 |
| HERC2 | -3739 |
| RBX1 | -3714 |
| CPNE1 | -3710 |
| CNTF | -3706 |
| LAT | -3697 |
| NLRC4 | -3690 |
| MTOR | -3683 |
| MCL1 | -3681 |
| PDAP1 | -3657 |
| GAN | -3641 |
| CD101 | -3638 |
| DCTN5 | -3634 |
| SH2B1 | -3615 |
| DYNC1H1 | -3614 |
| TXN | -3611 |
| LAG3 | -3610 |
| IL20RB | -3604 |
| TRIM41 | -3598 |
| ROCK1 | -3594 |
| POLR2H | -3593 |
| LIF | -3587 |
| CDKN1A | -3580 |
| TMEM179B | -3567 |
| KCTD7 | -3550 |
| SIRPA | -3538 |
| TRIM62 | -3535 |
| COMMD9 | -3531 |
| PRLR | -3529 |
| JUNB | -3526 |
| NFKB1 | -3507 |
| MYO5A | -3500 |
| AP2A2 | -3499 |
| UBE3D | -3465 |
| TRIM37 | -3461 |
| TRIM39 | -3437 |
| GOLGA7 | -3421 |
| DUSP6 | -3376 |
| KLC2 | -3375 |
| WASF2 | -3366 |
| CHUK | -3364 |
| STBD1 | -3361 |
| HSPA6 | -3353 |
| SIAH1 | -3347 |
| MAP2K3 | -3342 |
| ATG12 | -3333 |
| STIM1 | -3329 |
| MEF2A | -3308 |
| RNF14 | -3295 |
| MAOA | -3288 |
| KLHL2 | -3269 |
| TRIM11 | -3250 |
| CD59 | -3245 |
| SMARCA4 | -3226 |
| EDA2R | -3214 |
| IRF4 | -3173 |
| HEBP2 | -3167 |
| ZNRF2 | -3150 |
| PPL | -3149 |
| UBE2L3 | -3143 |
| PA2G4 | -3141 |
| ENAH | -3139 |
| SEM1 | -3130 |
| RAB5C | -3129 |
| LNPEP | -3128 |
| FN1 | -3115 |
| PSMA3 | -3078 |
| CUL3 | -3056 |
| GRB2 | -3047 |
| LYN | -3038 |
| TRIM35 | -3032 |
| RPS6KA3 | -3030 |
| LAIR1 | -3025 |
| ABL2 | -3020 |
| ELOB | -3004 |
| TXLNA | -3002 |
| SAR1B | -2973 |
| WIPF2 | -2965 |
| APOB | -2964 |
| PLAU | -2962 |
| AKT1 | -2958 |
| TMEM30A | -2956 |
| RCHY1 | -2947 |
| JUN | -2934 |
| IKBKB | -2931 |
| PSMD8 | -2928 |
| AP2S1 | -2922 |
| CBLB | -2897 |
| RBCK1 | -2891 |
| RIPK1 | -2886 |
| STK11IP | -2838 |
| CD99 | -2817 |
| PIK3CA | -2813 |
| GRN | -2805 |
| TOMM70 | -2797 |
| NCKAP1 | -2788 |
| VAMP7 | -2787 |
| DYNC1I2 | -2780 |
| ELMO1 | -2779 |
| RPS27A | -2773 |
| EEA1 | -2764 |
| RHOG | -2756 |
| JAK2 | -2719 |
| SEC23A | -2717 |
| PSMA5 | -2715 |
| HERC1 | -2688 |
| ADAM10 | -2671 |
| UBE2E3 | -2654 |
| S100P | -2653 |
| RNF34 | -2647 |
| RNF115 | -2643 |
| RELA | -2632 |
| LAMTOR3 | -2631 |
| FBXL14 | -2614 |
| RHOF | -2600 |
| PIK3CB | -2588 |
| UBE2B | -2586 |
| PSMD13 | -2577 |
| MAP3K14 | -2575 |
| FBXW7 | -2564 |
| UBE3A | -2547 |
| FBXW10 | -2540 |
| B2M | -2523 |
| DYNC1LI1 | -2519 |
| POLR3H | -2496 |
| SERPINB6 | -2474 |
| SP100 | -2455 |
| ATP11B | -2420 |
| QPCT | -2416 |
| CANT1 | -2398 |
| PSMC2 | -2389 |
| STX1A | -2377 |
| TLR9 | -2371 |
| MAP2K6 | -2351 |
| PSME1 | -2348 |
| IFNAR2 | -2313 |
| PRKDC | -2300 |
| PIK3R3 | -2279 |
| PRCP | -2276 |
| POLR3B | -2273 |
| UBA6 | -2266 |
| NECTIN2 | -2239 |
| PTPN4 | -2238 |
| IRAK1 | -2218 |
| C8G | -2213 |
| ARPC2 | -2209 |
| CDC42 | -2172 |
| ARHGAP9 | -2170 |
| PPP2R5D | -2117 |
| FBXL19 | -2110 |
| PRR5 | -2094 |
| RICTOR | -2076 |
| CRISPLD2 | -2075 |
| KLRK1 | -2060 |
| AGER | -2057 |
| POLR3A | -2056 |
| KRAS | -2044 |
| HECTD3 | -2034 |
| IFNLR1 | -2031 |
| FBXL3 | -2027 |
| GDI2 | -2026 |
| TP53 | -2020 |
| IST1 | -2001 |
| ANAPC13 | -1975 |
| UBE2W | -1973 |
| TICAM1 | -1956 |
| AKT2 | -1946 |
| DCTN4 | -1937 |
| NUP214 | -1926 |
| AP1G1 | -1916 |
| PSMB3 | -1915 |
| AP2A1 | -1902 |
| MAPK13 | -1875 |
| UBE2S | -1872 |
| UNC13D | -1871 |
| PELI2 | -1870 |
| RNF138 | -1859 |
| FBXO9 | -1843 |
| SDCBP | -1822 |
| LTN1 | -1814 |
| IMPDH1 | -1807 |
| PILRA | -1760 |
| BTNL9 | -1735 |
| POLR3C | -1730 |
| LTBR | -1719 |
| NPEPPS | -1702 |
| KPNA4 | -1701 |
| TRIM71 | -1686 |
| MMP3 | -1680 |
| CAND1 | -1658 |
| ANAPC2 | -1639 |
| DCTN1 | -1635 |
| HAVCR2 | -1603 |
| CAPZA2 | -1549 |
| ANAPC11 | -1544 |
| STAT6 | -1541 |
| SLC2A3 | -1535 |
| CDC27 | -1529 |
| MUC13 | -1524 |
| STOM | -1523 |
| ARIH1 | -1512 |
| ARPC5 | -1511 |
| PSMC3 | -1509 |
| FBXL18 | -1507 |
| LGALS9 | -1496 |
| NDC1 | -1490 |
| EGR1 | -1475 |
| MX2 | -1456 |
| PRKACB | -1429 |
| IL23A | -1422 |
| ORAI1 | -1417 |
| SEC61A2 | -1397 |
| UBR2 | -1393 |
| PIK3R2 | -1355 |
| SOCS2 | -1346 |
| YES1 | -1340 |
| LY96 | -1339 |
| TNIP2 | -1314 |
| NFKB2 | -1311 |
| SPSB2 | -1306 |
| EDA | -1292 |
| VRK3 | -1278 |
| UBA3 | -1275 |
| ICAM1 | -1264 |
| BRWD1 | -1263 |
| HERC4 | -1256 |
| QSOX1 | -1250 |
| LMO7 | -1246 |
| ATP6AP2 | -1245 |
| ORM2 | -1240 |
| CUL5 | -1229 |
| KLHL11 | -1223 |
| MYO1C | -1212 |
| ABI2 | -1197 |
| ADAM8 | -1193 |
| MGRN1 | -1188 |
| CAPZB | -1169 |
| GYG1 | -1167 |
| ERAP1 | -1151 |
| RPS6KA2 | -1149 |
| PSMB4 | -1144 |
| FBXL12 | -1137 |
| TRIM38 | -1131 |
| MT2A | -1121 |
| ITK | -1112 |
| RAP2C | -1109 |
| ASB8 | -1103 |
| BOLA2 | -1094 |
| TNFSF13 | -1035 |
| OSBPL1A | -1032 |
| HSP90AA1 | -1030 |
| MUC20 | -1019 |
| IFI27 | -1017 |
| KLHL5 | -991 |
| NCKAP1L | -972 |
| RLIM | -971 |
| UBE2Z | -964 |
| RNF114 | -963 |
| SOS1 | -950 |
| HNRNPDL | -933 |
| CD79A | -929 |
| DDX58 | -927 |
| MICB | -918 |
| SH3KBP1 | -917 |
| UBE2D2 | -913 |
| LCP1 | -901 |
| PSMA7 | -892 |
| YWHAZ | -885 |
| COTL1 | -877 |
| FBXL13 | -870 |
| ATP6V1F | -868 |
| PTPN11 | -867 |
| AMPD3 | -829 |
| GHDC | -827 |
| ABCE1 | -819 |
| IKBKE | -787 |
| CDKN1B | -786 |
| WWP1 | -779 |
| LAMTOR1 | -774 |
| PSMB5 | -742 |
| AP1S3 | -739 |
| UBE2G2 | -718 |
| SNAP29 | -703 |
| RNASET2 | -701 |
| MAPK8 | -700 |
| VAMP3 | -698 |
| DNAJC13 | -677 |
| CALM1 | -655 |
| TNFRSF9 | -640 |
| BAIAP2 | -637 |
| IL22RA1 | -612 |
| RNF7 | -611 |
| ASB18 | -601 |
| MAN2B1 | -600 |
| SIGLEC10 | -594 |
| INPPL1 | -587 |
| TRAF2 | -577 |
| RASGRP3 | -569 |
| DHX36 | -566 |
| TAP2 | -558 |
| NCSTN | -554 |
| SKP1 | -544 |
| IFITM1 | -540 |
| ATP6V1E2 | -534 |
| ZEB1 | -533 |
| UNC93B1 | -517 |
| BIRC2 | -499 |
| LRR1 | -494 |
| STX4 | -491 |
| CD19 | -472 |
| PAFAH1B2 | -471 |
| RELB | -469 |
| PSMD11 | -432 |
| TAP1 | -414 |
| TRIM29 | -412 |
| UBE2R2 | -386 |
| RNF4 | -377 |
| RAB18 | -372 |
| TNFSF15 | -357 |
| TRAF3 | -356 |
| IRF2 | -335 |
| NUP160 | -329 |
| DCTN6 | -318 |
| ADGRE5 | -313 |
| UBAC1 | -312 |
| AREL1 | -303 |
| NUP62 | -299 |
| FBXW2 | -294 |
| PIAS1 | -272 |
| B4GALT1 | -262 |
| CMTM6 | -259 |
| PGRMC1 | -242 |
| GMFG | -220 |
| KLHL25 | -215 |
| CDC26 | -197 |
| IL17RA | -186 |
| CASP4 | -184 |
| KCTD6 | -178 |
| TRIM46 | -171 |
| REL | -160 |
| LAMTOR2 | -148 |
| CCND1 | -137 |
| PILRB | -136 |
| TAPBP | -130 |
| PSMA6 | -126 |
| CPN2 | -110 |
| FBXO2 | -78 |
| CRACR2A | -75 |
| PRDX6 | -54 |
| CREG1 | -47 |
| RANBP2 | -4 |
| FBXO10 | 18 |
| AHSG | 25 |
| XRCC6 | 28 |
| BTBD1 | 37 |
| CSF2RA | 43 |
| RAC1 | 44 |
| CXADR | 72 |
| STAT2 | 76 |
| DGAT1 | 111 |
| IL27RA | 122 |
| CTSE | 125 |
| RNF135 | 126 |
| NLRP1 | 136 |
| FBXO30 | 137 |
| NKIRAS1 | 150 |
| ICAM4 | 161 |
| TCIRG1 | 180 |
| NEDD4 | 196 |
| FZR1 | 201 |
| MAPK11 | 251 |
| KPNA5 | 258 |
| PGM2 | 263 |
| IL16 | 266 |
| PPP2R5E | 283 |
| TNFRSF25 | 296 |
| ANAPC4 | 305 |
| RAP1A | 309 |
| STK10 | 333 |
| IL1RL1 | 347 |
| CUL2 | 359 |
| CD226 | 372 |
| FCER1G | 380 |
| PPP3CA | 381 |
| UBE2K | 383 |
| PDPK1 | 399 |
| IL12RB1 | 421 |
| PSMB10 | 423 |
| RAPGEF4 | 438 |
| CREB1 | 474 |
| UBA1 | 516 |
| COLEC12 | 522 |
| CRKL | 524 |
| TPR | 565 |
| CCL22 | 584 |
| IL15 | 586 |
| ZNRF1 | 590 |
| CYB5R3 | 600 |
| FRK | 602 |
| FBXL15 | 612 |
| RNF25 | 622 |
| F2 | 635 |
| ELOC | 645 |
| LAT2 | 670 |
| KCNAB2 | 675 |
| POLR3F | 688 |
| ATP6V1G2 | 690 |
| NOS1 | 709 |
| BST1 | 713 |
| ICAM5 | 728 |
| GHR | 733 |
| STXBP2 | 740 |
| ATP6V0D2 | 747 |
| TNFSF9 | 763 |
| CSTB | 776 |
| UBC | 779 |
| SLC27A2 | 829 |
| SEC22B | 859 |
| IRF3 | 862 |
| FBXW9 | 890 |
| IL1R2 | 892 |
| AP1M2 | 914 |
| NFKBIE | 919 |
| AP1B1 | 940 |
| ELMO2 | 942 |
| FBXO7 | 947 |
| CD40 | 949 |
| PCBP2 | 974 |
| CRCP | 979 |
| NAPRT | 988 |
| IFNGR2 | 997 |
| RNF220 | 999 |
| LGMN | 1001 |
| PAK1 | 1031 |
| PML | 1051 |
| PSMB1 | 1054 |
| SPSB1 | 1077 |
| JAML | 1090 |
| PECAM1 | 1098 |
| SIRPB1 | 1105 |
| TLR6 | 1131 |
| PIK3R4 | 1132 |
| EIF4A3 | 1154 |
| CD74 | 1162 |
| NANOG | 1164 |
| CDC16 | 1175 |
| CIITA | 1176 |
| HECTD2 | 1208 |
| OPRD1 | 1233 |
| PLD3 | 1239 |
| GUSB | 1260 |
| POU2F1 | 1266 |
| APAF1 | 1277 |
| CCNF | 1291 |
| RAB6A | 1296 |
| PPIE | 1333 |
| GBP4 | 1334 |
| MOSPD2 | 1344 |
| MICA | 1351 |
| NUP133 | 1362 |
| BTRC | 1386 |
| ADGRG3 | 1417 |
| UBE4A | 1433 |
| ACTR2 | 1435 |
| IL17RC | 1440 |
| RNF217 | 1448 |
| DCTN3 | 1457 |
| CXCR2 | 1464 |
| ATP11A | 1486 |
| GSN | 1496 |
| CTSS | 1499 |
| SIGIRR | 1500 |
| NCK1 | 1525 |
| POLR3G | 1545 |
| GLB1 | 1557 |
| USP41 | 1563 |
| LIMK1 | 1565 |
| IRAK4 | 1591 |
| TRAF6 | 1597 |
| RAB3D | 1600 |
| IFNGR1 | 1624 |
| RAB10 | 1625 |
| SUGT1 | 1662 |
| HTN1 | 1687 |
| MAVS | 1695 |
| CAMK2D | 1711 |
| PRKACA | 1736 |
| MAPK9 | 1760 |
| SCAMP1 | 1817 |
| HSPA1A | 1835 |
| UBE2N | 1836 |
| GLMN | 1839 |
| KIF3C | 1853 |
| HERC5 | 1855 |
| MLST8 | 1875 |
| PSMB2 | 1876 |
| CLEC7A | 1881 |
| FADD | 1889 |
| MYC | 1892 |
| ITGAX | 1919 |
| BCL2 | 1925 |
| PDE12 | 1929 |
| FYN | 1937 |
| CYFIP1 | 1939 |
| IL6ST | 1965 |
| PTPRN2 | 1971 |
| TNFSF14 | 1985 |
| LRRC41 | 1992 |
| ANAPC1 | 1998 |
| ABL1 | 2023 |
| AP2B1 | 2029 |
| YWHAB | 2082 |
| IL18 | 2102 |
| ATP7A | 2111 |
| UBE2E2 | 2114 |
| CAMK2G | 2145 |
| KLRD1 | 2155 |
| SDC1 | 2160 |
| CTSV | 2161 |
| AGL | 2176 |
| SVIP | 2180 |
| SERPINB1 | 2181 |
| CYBA | 2202 |
| ITPR2 | 2257 |
| KIF5C | 2266 |
| MAPK14 | 2269 |
| KLRG1 | 2270 |
| GSTO1 | 2273 |
| FOXO3 | 2282 |
| EIF4E3 | 2306 |
| NRAS | 2310 |
| MGST1 | 2313 |
| JUP | 2314 |
| CARD9 | 2322 |
| NUP58 | 2380 |
| SPTAN1 | 2385 |
| ARMC8 | 2401 |
| SLC15A4 | 2407 |
| UBR1 | 2428 |
| UBOX5 | 2442 |
| RNF111 | 2443 |
| EVL | 2467 |
| MEFV | 2468 |
| EIF4E | 2473 |
| HTN3 | 2502 |
| DYNLL1 | 2509 |
| PLCG1 | 2511 |
| PLAC8 | 2524 |
| GBP5 | 2542 |
| TAB3 | 2566 |
| FSCN1 | 2591 |
| WASF3 | 2619 |
| UBE2Q2 | 2642 |
| UFL1 | 2652 |
| PJA1 | 2653 |
| CPPED1 | 2657 |
| FUCA1 | 2696 |
| NUP153 | 2712 |
| TNFRSF14 | 2741 |
| PPP2R5C | 2743 |
| HLA-B | 2764 |
| PAG1 | 2774 |
| NUP43 | 2808 |
| MID1 | 2810 |
| CTSD | 2812 |
| VAV2 | 2817 |
| IRF5 | 2827 |
| FLNB | 2867 |
| BST2 | 2868 |
| ARSA | 2878 |
| EIF2AK2 | 2886 |
| RAB5B | 2913 |
| FBXL8 | 2924 |
| AP1M1 | 2926 |
| ATG5 | 2931 |
| KBTBD8 | 2943 |
| MAPK10 | 2952 |
| AAAS | 2965 |
| RAB27A | 3011 |
| ARPC1A | 3022 |
| ASB3 | 3026 |
| DTX4 | 3048 |
| PIN1 | 3074 |
| RPS6KA5 | 3086 |
| TRAPPC1 | 3089 |
| KLC3 | 3105 |
| FBXL22 | 3108 |
| PDCD4 | 3127 |
| POLR3K | 3152 |
| CASP8 | 3157 |
| RAB4B | 3174 |
| UBE2D4 | 3190 |
| SLC2A5 | 3250 |
| CTNNB1 | 3272 |
| IFITM2 | 3282 |
| KIF3A | 3299 |
| CPNE3 | 3303 |
| SUMO1 | 3308 |
| NUP54 | 3310 |
| RAP1GAP2 | 3326 |
| KLHL20 | 3344 |
| IL4R | 3348 |
| TMEM63A | 3357 |
| UBE2V2 | 3369 |
| STUB1 | 3373 |
| DBNL | 3382 |
| PDZD11 | 3385 |
| APRT | 3389 |
| TRIM50 | 3393 |
| HERC3 | 3443 |
| BIRC3 | 3477 |
| C5AR2 | 3489 |
| IRS1 | 3502 |
| GBP1 | 3503 |
| UBE2D1 | 3523 |
| SLC11A1 | 3527 |
| DOCK1 | 3540 |
| FBXO15 | 3559 |
| MANBA | 3572 |
| RAP1B | 3577 |
| TIFA | 3587 |
| TRPC1 | 3602 |
| PTGES2 | 3607 |
| PTPN1 | 3622 |
| FBXO27 | 3623 |
| CXCL8 | 3625 |
| RAB14 | 3647 |
| ATOX1 | 3659 |
| CRLF1 | 3695 |
| KLHL9 | 3712 |
| FBXW8 | 3716 |
| CST3 | 3732 |
| UBE2E1 | 3733 |
| IL7 | 3739 |
| UBE2A | 3752 |
| MAP3K7 | 3767 |
| ARPC3 | 3797 |
| LYZ | 3804 |
| DYNLT1 | 3809 |
| IL17RE | 3847 |
| SPTBN2 | 3883 |
| HVCN1 | 3884 |
| ACAA1 | 3886 |
| KLC4 | 3897 |
| INPP5D | 3931 |
| FBXO6 | 3932 |
| ANAPC5 | 3942 |
| SRC | 3962 |
| SERPINA1 | 4014 |
| FABP5 | 4021 |
| RAB24 | 4024 |
| CPN1 | 4039 |
| PLD2 | 4048 |
| NBEAL2 | 4086 |
| MRE11 | 4100 |
| TRIM21 | 4105 |
| MTAP | 4110 |
| IFNAR1 | 4161 |
| NUP85 | 4178 |
| FBXO4 | 4180 |
| HLA-H | 4193 |
| CASP2 | 4204 |
| CTF1 | 4240 |
| RNF216 | 4252 |
| STAT3 | 4253 |
| C2 | 4264 |
| KLHL13 | 4291 |
| PSMD12 | 4303 |
| RAB3A | 4309 |
| IL12A | 4312 |
| CPB2 | 4337 |
| SAMHD1 | 4346 |
| TNFAIP3 | 4359 |
| METTL7A | 4368 |
| CUL7 | 4377 |
| SIKE1 | 4383 |
| RAE1 | 4394 |
| VCL | 4407 |
| CSNK2B | 4415 |
| TIRAP | 4446 |
| UBE3B | 4451 |
| POLR3D | 4454 |
| CD8A | 4468 |
| ERAP2 | 4482 |
| PLAUR | 4485 |
| PTAFR | 4486 |
| ATP6V1B1 | 4549 |
| TRIM69 | 4557 |
| ACLY | 4562 |
| CAMK2A | 4566 |
| PSMD4 | 4567 |
| RHOU | 4579 |
| HMOX1 | 4592 |
| DPP7 | 4601 |
| KLC1 | 4611 |
| PPP2R1B | 4614 |
| ANPEP | 4690 |
| IL11RA | 4693 |
| GAA | 4697 |
| APEH | 4698 |
| NFATC2 | 4720 |
| C7 | 4745 |
| IL15RA | 4756 |
| FBXO22 | 4762 |
| AGPAT2 | 4769 |
| TNFRSF13C | 4785 |
| NUP155 | 4796 |
| FBXL4 | 4801 |
| TNFRSF1A | 4807 |
| TNFSF12 | 4816 |
| MUC15 | 4828 |
| AHCYL1 | 4874 |
| EPPIN | 4893 |
| PYGL | 4903 |
| IMPDH2 | 4910 |
| PSMD10 | 4933 |
| PSMD7 | 4942 |
| NLRC5 | 4976 |
| FBXO21 | 4978 |
| COMMD3 | 4983 |
| CAT | 5018 |
| PELI3 | 5019 |
| CD46 | 5036 |
| ORMDL3 | 5040 |
| ALPK1 | 5041 |
| SOCS1 | 5053 |
| ICOSLG | 5061 |
| TYK2 | 5066 |
| KLHL22 | 5084 |
| PSMD5 | 5116 |
| TUBB | 5125 |
| ASB9 | 5150 |
| LPCAT1 | 5166 |
| GSTA2 | 5171 |
| BIRC5 | 5174 |
| IRF1 | 5197 |
| RBSN | 5208 |
| C4BPA | 5221 |
| KIF18A | 5234 |
| TRIM3 | 5236 |
| CD36 | 5264 |
| GM2A | 5280 |
| STAT5A | 5288 |
| MX1 | 5298 |
| DERA | 5319 |
| PTPN9 | 5324 |
| IL13RA1 | 5359 |
| IL1RAP | 5361 |
| UBE2H | 5369 |
| MADCAM1 | 5372 |
| TBC1D10C | 5382 |
| OSMR | 5392 |
| GSDMD | 5413 |
| FOXO1 | 5418 |
| IL32 | 5419 |
| PFKL | 5437 |
| NOD1 | 5449 |
| ATG7 | 5453 |
| DTX3L | 5458 |
| NCKIPSD | 5477 |
| NPDC1 | 5488 |
| PSMB9 | 5491 |
| XAF1 | 5517 |
| CENPE | 5538 |
| HMGB1 | 5546 |
| VNN1 | 5548 |
| CFD | 5558 |
| ULBP1 | 5560 |
| ACTR10 | 5570 |
| RNF213 | 5584 |
| EIF4A2 | 5593 |
| NIT2 | 5596 |
| BLMH | 5642 |
| CLU | 5647 |
| CDC20 | 5650 |
| CTSH | 5655 |
| FBXL5 | 5669 |
| SLCO4C1 | 5675 |
| ATP6V0E2 | 5683 |
| LBP | 5684 |
| TRIM36 | 5698 |
| IL10RB | 5733 |
| MASP2 | 5751 |
| ACTR1B | 5765 |
| HLA-A | 5777 |
| SOD1 | 5779 |
| CEP290 | 5787 |
| RACGAP1 | 5789 |
| EBI3 | 5791 |
| AP1S1 | 5804 |
| NUP93 | 5831 |
| USP18 | 5875 |
| HGSNAT | 5921 |
| KIF20A | 5931 |
| HLA-C | 5936 |
| MYD88 | 5939 |
| LONRF1 | 5944 |
| SKP2 | 5946 |
| PSTPIP1 | 5948 |
| IFIT3 | 5949 |
| POLR2K | 5962 |
| ALDOC | 5970 |
| HERC6 | 5973 |
| PSMD14 | 5974 |
| TRIM32 | 5977 |
| KIF2C | 5981 |
| NUP35 | 5982 |
| FBXO17 | 5986 |
| UNKL | 5989 |
| ATP8A1 | 5995 |
| FLT3LG | 6000 |
| CISH | 6003 |
| CLEC2D | 6035 |
| KIF15 | 6037 |
| FBXW4 | 6039 |
| DYNLL2 | 6044 |
| PROS1 | 6053 |
| KIF4A | 6056 |
| DHX58 | 6062 |
| ANAPC10 | 6071 |
| CD4 | 6074 |
| NUP107 | 6076 |
| THEM4 | 6080 |
| PLA2G6 | 6084 |
| CD47 | 6101 |
| CASP1 | 6109 |
| CDC23 | 6113 |
| FBXO41 | 6136 |
| C6orf120 | 6141 |
| AGA | 6147 |
| ANXA2 | 6155 |
| TRIM56 | 6183 |
| RNF41 | 6188 |
| TRIM2 | 6197 |
| UBA7 | 6211 |
| CYFIP2 | 6224 |
| LTA4H | 6248 |
| ANAPC7 | 6249 |
| LRSAM1 | 6259 |
| DNASE1L1 | 6262 |
| NLRX1 | 6266 |
| TRIM14 | 6269 |
| TNFRSF11A | 6300 |
| RNF144B | 6303 |
| DET1 | 6311 |
| KIF23 | 6313 |
| ALAD | 6318 |
| ITGAL | 6325 |
| IFIT1 | 6374 |
| ASB13 | 6386 |
| TRIM22 | 6415 |
| IL34 | 6416 |
| BTN2A2 | 6418 |
| CD68 | 6463 |
| ITGB2 | 6494 |
| DNM1 | 6505 |
| IL1R1 | 6510 |
| BPIFB1 | 6516 |
| PTPN6 | 6557 |
| HACE1 | 6570 |
| STAT5B | 6572 |
| KIFAP3 | 6573 |
| KIF11 | 6577 |
| IFI35 | 6618 |
| C6 | 6620 |
| LAMA5 | 6638 |
| MAPK3 | 6640 |
| IFIH1 | 6646 |
| TAB1 | 6687 |
| FGG | 6697 |
| SYNGR1 | 6711 |
| IFIT5 | 6717 |
| C5AR1 | 6719 |
| LRG1 | 6726 |
| HP | 6732 |
| CDA | 6735 |
| TUBB4B | 6758 |
| KBTBD7 | 6772 |
| KBTBD6 | 6796 |
| NUP210 | 6802 |
| PTK2B | 6809 |
| DZIP3 | 6813 |
| PTPN18 | 6851 |
| S100A1 | 6858 |
| ALDH3B1 | 6860 |
| CEBPD | 6867 |
| ICAM2 | 6868 |
| SLC44A2 | 6879 |
| TRIM45 | 6884 |
| CFI | 6891 |
| BTN3A3 | 6893 |
| PYCARD | 6900 |
| VTN | 6910 |
| MBL2 | 6911 |
| DSN1 | 6916 |
| TRAIP | 6925 |
| KIF22 | 6933 |
| RAB37 | 6989 |
| CD14 | 6998 |
| RORC | 7056 |
| A1BG | 7060 |
| NUP37 | 7100 |
| LMNB1 | 7101 |
| IL1RN | 7124 |
| BTN3A1 | 7132 |
| UBE2C | 7137 |
| BTN3A2 | 7149 |
| NHLRC3 | 7191 |
| C1R | 7201 |
| SLA2 | 7214 |
| C5 | 7218 |
| FGB | 7226 |
| NEDD4L | 7233 |
| C8A | 7235 |
| PLA2G2A | 7254 |
| GCA | 7258 |
| TKFC | 7267 |
| FBXL16 | 7269 |
| UBE2L6 | 7272 |
| C4B | 7286 |
| PLD1 | 7290 |
| CDH1 | 7296 |
| POLR3GL | 7315 |
| RNF125 | 7321 |
| JAK3 | 7326 |
| SERPINA3 | 7328 |
| LEAP2 | 7329 |
| FGA | 7336 |
| SOD2 | 7342 |
| C8B | 7343 |
| C4A | 7346 |
| CFB | 7350 |
| CSF3R | 7351 |
| C3 | 7357 |
| IL21R | 7359 |
| C1S | 7360 |
| SOCS3 | 7374 |
| MUC5B | 7378 |
| TXNIP | 7384 |
| SERPING1 | 7387 |
SARS-CoV Infections
| 1021 | |
|---|---|
| set | SARS-CoV Infections |
| setSize | 144 |
| pANOVA | 1.05e-10 |
| s.dist | -0.312 |
| p.adjustANOVA | 4.26e-09 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CANX | -7092 |
| MAGT1 | -7045 |
| MAP1LC3B | -7040 |
| RPN1 | -7013 |
| CTSL | -6951 |
| ATP1B3 | -6941 |
| ST3GAL4 | -6801 |
| STT3A | -6796 |
| ATP1A1 | -6777 |
| ST6GALNAC4 | -6726 |
| VCP | -6720 |
| FURIN | -6683 |
| DDX5 | -6665 |
| ATP1B1 | -6624 |
| CHMP4C | -6557 |
| VHL | -6491 |
| KEAP1 | -6482 |
| BRD4 | -6479 |
| DDOST | -6429 |
| MGAT1 | -6401 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CANX | -7092 |
| MAGT1 | -7045 |
| MAP1LC3B | -7040 |
| RPN1 | -7013 |
| CTSL | -6951 |
| ATP1B3 | -6941 |
| ST3GAL4 | -6801 |
| STT3A | -6796 |
| ATP1A1 | -6777 |
| ST6GALNAC4 | -6726 |
| VCP | -6720 |
| FURIN | -6683 |
| DDX5 | -6665 |
| ATP1B1 | -6624 |
| CHMP4C | -6557 |
| VHL | -6491 |
| KEAP1 | -6482 |
| BRD4 | -6479 |
| DDOST | -6429 |
| MGAT1 | -6401 |
| BRMS1 | -6309 |
| UVRAG | -6290 |
| FNTA | -6282 |
| MGAT4B | -6279 |
| DAD1 | -6240 |
| RPN2 | -6193 |
| PRKCSH | -5934 |
| ST3GAL1 | -5905 |
| FXYD2 | -5865 |
| MGAT5 | -5854 |
| FKBP4 | -5807 |
| MTA2 | -5619 |
| EDEM2 | -5520 |
| CSNK1A1 | -5349 |
| SAP30 | -5230 |
| PIK3C3 | -5220 |
| FKBP1A | -5189 |
| TBK1 | -5169 |
| FUT8 | -5134 |
| GSK3B | -5101 |
| UBA52 | -5068 |
| CHMP4B | -5021 |
| MGAT4A | -5018 |
| JAK1 | -4963 |
| IL6R | -4943 |
| CHD4 | -4830 |
| AP2M1 | -4603 |
| MBD3 | -4543 |
| ST3GAL2 | -4518 |
| VEGFA | -4456 |
| HSP90AB1 | -4426 |
| PRMT1 | -4281 |
| UBB | -4263 |
| ITGB1 | -4145 |
| GATAD2A | -4108 |
| NR3C1 | -4005 |
| SAP30L | -3887 |
| PARP16 | -3842 |
| RBX1 | -3714 |
| ATP1B2 | -3692 |
| GSK3A | -3684 |
| ROCK1 | -3594 |
| MAN1B1 | -3561 |
| AP2A2 | -3499 |
| RCOR1 | -3493 |
| SAP18 | -3349 |
| MGAT2 | -3327 |
| RBBP4 | -3297 |
| HMG20B | -3184 |
| CUL3 | -3056 |
| AP2S1 | -2922 |
| BECN1 | -2900 |
| RIPK1 | -2886 |
| FXYD1 | -2847 |
| RPS27A | -2773 |
| ROCK2 | -2772 |
| JAK2 | -2719 |
| HDAC1 | -2676 |
| FNTB | -2551 |
| TLR9 | -2371 |
| IFNAR2 | -2313 |
| SUDS3 | -2287 |
| MOGS | -2275 |
| NFE2L2 | -2108 |
| CRBN | -1928 |
| SRPK2 | -1905 |
| AP2A1 | -1902 |
| ST6GAL1 | -1828 |
| IMPDH1 | -1807 |
| ATP1A3 | -1706 |
| PARP6 | -1567 |
| CHD3 | -1321 |
| UBE2I | -1318 |
| TUSC3 | -1219 |
| GATAD2B | -1092 |
| CHMP2A | -1088 |
| PHF21A | -1078 |
| MAN2A1 | -1040 |
| HSP90AA1 | -1030 |
| CHMP2B | -878 |
| GALNT1 | -816 |
| REST | -593 |
| HDAC2 | -338 |
| ARID4A | -156 |
| STAT2 | 76 |
| ATP1A4 | 412 |
| PARP4 | 462 |
| RB1 | 470 |
| ARID4B | 480 |
| SIGMAR1 | 753 |
| UBC | 779 |
| CHMP4A | 909 |
| IFNGR2 | 997 |
| PIK3R4 | 1132 |
| CHMP3 | 1229 |
| TMPRSS2 | 1456 |
| IFNGR1 | 1624 |
| MGAT4C | 1714 |
| MTA1 | 1810 |
| AP2B1 | 2029 |
| CYSLTR1 | 2493 |
| COMT | 2597 |
| CHMP7 | 2690 |
| ACE2 | 2757 |
| GANAB | 2813 |
| SRPK1 | 3007 |
| PARP8 | 3263 |
| SUMO1 | 3308 |
| PTGES3 | 3734 |
| IFNAR1 | 4161 |
| KDM1A | 4224 |
| ZCRB1 | 4731 |
| IMPDH2 | 4910 |
| TYK2 | 5066 |
| TUBB | 5125 |
| RBBP7 | 5134 |
| PARP14 | 5386 |
| PARP10 | 5859 |
| CHMP6 | 5904 |
| ST3GAL3 | 5918 |
| MTA3 | 6411 |
| IL1R1 | 6510 |
| PARP9 | 6988 |
| JAK3 | 7326 |
Unfolded Protein Response (UPR)
| 1318 | |
|---|---|
| set | Unfolded Protein Response (UPR) |
| setSize | 89 |
| pANOVA | 1.43e-10 |
| s.dist | -0.393 |
| p.adjustANOVA | 5.62e-09 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| HSPA5 | -7144 |
| CALR | -7142 |
| DNAJB11 | -7141 |
| HYOU1 | -7140 |
| HERPUD1 | -7137 |
| DNAJC3 | -7131 |
| HSP90B1 | -7129 |
| DNAJB9 | -7125 |
| SYVN1 | -7108 |
| PDIA6 | -7106 |
| EDEM1 | -7103 |
| WFS1 | -7096 |
| GFPT1 | -7051 |
| DDIT3 | -7047 |
| EIF2AK3 | -7028 |
| MYDGF | -6976 |
| SERP1 | -6964 |
| ATF6 | -6949 |
| WIPI1 | -6942 |
| SHC1 | -6910 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HSPA5 | -7144 |
| CALR | -7142 |
| DNAJB11 | -7141 |
| HYOU1 | -7140 |
| HERPUD1 | -7137 |
| DNAJC3 | -7131 |
| HSP90B1 | -7129 |
| DNAJB9 | -7125 |
| SYVN1 | -7108 |
| PDIA6 | -7106 |
| EDEM1 | -7103 |
| WFS1 | -7096 |
| GFPT1 | -7051 |
| DDIT3 | -7047 |
| EIF2AK3 | -7028 |
| MYDGF | -6976 |
| SERP1 | -6964 |
| ATF6 | -6949 |
| WIPI1 | -6942 |
| SHC1 | -6910 |
| ATP6V0D1 | -6908 |
| SSR1 | -6907 |
| FKBP14 | -6896 |
| SRPRB | -6893 |
| ERN1 | -6872 |
| CREB3L2 | -6832 |
| TSPYL2 | -6784 |
| HDGF | -6715 |
| EXOSC6 | -6503 |
| TATDN2 | -6467 |
| TPP1 | -6407 |
| TLN1 | -6146 |
| CXXC1 | -6033 |
| CEBPG | -5987 |
| ADD1 | -5966 |
| MBTPS1 | -5958 |
| SEC31A | -5766 |
| ATF4 | -5664 |
| EIF2S1 | -5190 |
| PPP2R5B | -5131 |
| DCP2 | -5125 |
| SRPRA | -4802 |
| EXOSC5 | -4766 |
| CREBRF | -4582 |
| PARN | -4578 |
| CTDSP2 | -4462 |
| EIF2S2 | -4458 |
| IGFBP1 | -3931 |
| KLHDC3 | -3802 |
| LMNA | -3717 |
| GSK3A | -3684 |
| EIF2S3 | -3669 |
| CREB3 | -3650 |
| EXOSC3 | -3453 |
| ZBTB17 | -3194 |
| NFYA | -2482 |
| DCTN1 | -1635 |
| ARFGAP1 | -1587 |
| DIS3 | -1573 |
| CEBPB | -1129 |
| KHSRP | -994 |
| NFYC | -690 |
| YIF1A | 195 |
| EXOSC8 | 472 |
| PDIA5 | 579 |
| KDELR3 | 976 |
| SULT1A3 | 1040 |
| GOSR2 | 1238 |
| PREB | 1446 |
| ATF3 | 2488 |
| EXOSC4 | 3220 |
| EXOSC9 | 3293 |
| EXTL2 | 3353 |
| EXOSC1 | 3486 |
| EXTL3 | 3575 |
| CXCL8 | 3625 |
| MBTPS2 | 3687 |
| EXOSC2 | 3779 |
| ACADVL | 4157 |
| CUL7 | 4377 |
| PLA2G4B | 4716 |
| NFYB | 5091 |
| EXOSC7 | 5196 |
| CREB3L4 | 5920 |
| XBP1 | 5937 |
| CREB3L3 | 5999 |
| ASNS | 6208 |
| DDX11 | 6254 |
| EXTL1 | 6941 |
Major pathway of rRNA processing in the nucleolus and cytosol
| 609 | |
|---|---|
| set | Major pathway of rRNA processing in the nucleolus and cytosol |
| setSize | 174 |
| pANOVA | 1.91e-10 |
| s.dist | -0.28 |
| p.adjustANOVA | 7.29e-09 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| MPHOSPH10 | -6827 |
| DDX49 | -6809 |
| EXOSC6 | -6503 |
| RRP36 | -6354 |
| RIOK3 | -6332 |
| UTP14C | -6243 |
| UTP4 | -6111 |
| UTP14A | -5799 |
| PNO1 | -5758 |
| CSNK1D | -5722 |
| LTV1 | -5474 |
| GNL3 | -5332 |
| RPL19 | -5254 |
| DHX37 | -5250 |
| NOP14 | -5209 |
| RPS7 | -5138 |
| RRP1 | -5133 |
| UBA52 | -5068 |
| RPL11 | -5032 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| MPHOSPH10 | -6827 |
| DDX49 | -6809 |
| EXOSC6 | -6503 |
| RRP36 | -6354 |
| RIOK3 | -6332 |
| UTP14C | -6243 |
| UTP4 | -6111 |
| UTP14A | -5799 |
| PNO1 | -5758 |
| CSNK1D | -5722 |
| LTV1 | -5474 |
| GNL3 | -5332 |
| RPL19 | -5254 |
| DHX37 | -5250 |
| NOP14 | -5209 |
| RPS7 | -5138 |
| RRP1 | -5133 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| NOL9 | -4954 |
| IMP4 | -4940 |
| RPS5 | -4778 |
| BMS1 | -4769 |
| EXOSC5 | -4766 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| IMP3 | -4633 |
| UTP18 | -4476 |
| RPLP1 | -4391 |
| BOP1 | -4381 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| TEX10 | -4283 |
| WDR43 | -4193 |
| RPL35A | -4159 |
| RPL30 | -4081 |
| DDX47 | -4068 |
| RPS9 | -4028 |
| RIOK2 | -4018 |
| RPL18 | -3961 |
| DDX52 | -3894 |
| RPL26L1 | -3873 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| NOL12 | -3773 |
| NOB1 | -3772 |
| ISG20L2 | -3623 |
| EBNA1BP2 | -3613 |
| RPL28 | -3546 |
| RPSA | -3520 |
| PES1 | -3505 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| EXOSC3 | -3453 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| XRN2 | -3427 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| RPS15A | -3019 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| PELP1 | -2894 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| UTP20 | -2811 |
| RPS27A | -2773 |
| FCF1 | -2713 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| BYSL | -2637 |
| RPL41 | -2635 |
| RRP9 | -2591 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| UTP15 | -2509 |
| ERI1 | -2490 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| NIP7 | -2165 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| PWP2 | -2005 |
| RPL23 | -1913 |
| NCL | -1840 |
| UTP6 | -1836 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| DIS3 | -1573 |
| NOC4L | -1552 |
| FBL | -1548 |
| SENP3 | -1399 |
| UTP11 | -1337 |
| HEATR1 | -1324 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| NOP56 | -1145 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| RCL1 | -942 |
| RPS25 | -937 |
| TSR1 | -851 |
| TBL3 | -794 |
| RPL13 | -706 |
| RPL5 | -495 |
| EXOSC10 | -341 |
| DDX21 | -256 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| SNU13 | -129 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPS26 | 419 |
| EXOSC8 | 472 |
| RBM28 | 771 |
| KRR1 | 924 |
| RPP14 | 1309 |
| RPL21 | 1385 |
| RPP30 | 1439 |
| RPP38 | 1564 |
| RPP40 | 1770 |
| NOL6 | 1999 |
| RRP7A | 2006 |
| FTSJ3 | 2052 |
| WDR18 | 2127 |
| RPL22 | 2142 |
| RIOK1 | 2711 |
| RPL36A | 2875 |
| EXOSC4 | 3220 |
| CSNK1E | 3247 |
| EXOSC9 | 3293 |
| PDCD11 | 3334 |
| C1D | 3482 |
| EXOSC1 | 3486 |
| WDR75 | 3573 |
| EXOSC2 | 3779 |
| WDR12 | 3814 |
| NOL11 | 4020 |
| UTP3 | 4280 |
| DCAF13 | 4652 |
| WDR46 | 4709 |
| EXOSC7 | 5196 |
| NOP58 | 5612 |
| MPHOSPH6 | 5619 |
| WDR3 | 5692 |
| WDR36 | 5735 |
| LAS1L | 7022 |
| EMG1 | 7347 |
Eukaryotic Translation Termination
| 338 | |
|---|---|
| set | Eukaryotic Translation Termination |
| setSize | 89 |
| pANOVA | 2.8e-10 |
| s.dist | -0.387 |
| p.adjustANOVA | 1.04e-08 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| ETF1 | -6952 |
| GSPT1 | -6825 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| ETF1 | -6952 |
| GSPT1 | -6825 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| RPL30 | -4081 |
| RPS9 | -4028 |
| RPL18 | -3961 |
| RPL26L1 | -3873 |
| TRMT112 | -3869 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| RPL28 | -3546 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| RPS15A | -3019 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| RPS27A | -2773 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| RPL23 | -1913 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| RPS25 | -937 |
| RPL13 | -706 |
| RPL5 | -495 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPS26 | 419 |
| RPL21 | 1385 |
| RPL22 | 2142 |
| RPL36A | 2875 |
| APEH | 4698 |
| N6AMT1 | 7144 |
Vesicle-mediated transport
| 1327 | |
|---|---|
| set | Vesicle-mediated transport |
| setSize | 555 |
| pANOVA | 7.17e-10 |
| s.dist | -0.154 |
| p.adjustANOVA | 2.6e-08 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CALR | -7142 |
| HYOU1 | -7140 |
| SEC24D | -7134 |
| HSP90B1 | -7129 |
| RABGEF1 | -7111 |
| TMED2 | -7071 |
| MCFD2 | -7065 |
| ARRB1 | -7062 |
| MIA3 | -7049 |
| USP6NL | -7041 |
| MAP1LC3B | -7040 |
| AAK1 | -7032 |
| ANKRD27 | -6996 |
| RHOQ | -6969 |
| TMED7 | -6933 |
| VTI1A | -6899 |
| SEC24A | -6839 |
| GNS | -6813 |
| SEC13 | -6812 |
| ANK2 | -6778 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CALR | -7142 |
| HYOU1 | -7140 |
| SEC24D | -7134 |
| HSP90B1 | -7129 |
| RABGEF1 | -7111 |
| TMED2 | -7071 |
| MCFD2 | -7065 |
| ARRB1 | -7062 |
| MIA3 | -7049 |
| USP6NL | -7041 |
| MAP1LC3B | -7040 |
| AAK1 | -7032 |
| ANKRD27 | -6996 |
| RHOQ | -6969 |
| TMED7 | -6933 |
| VTI1A | -6899 |
| SEC24A | -6839 |
| GNS | -6813 |
| SEC13 | -6812 |
| ANK2 | -6778 |
| TMEM115 | -6764 |
| RAB43 | -6699 |
| FTL | -6697 |
| SNX2 | -6677 |
| RHOBTB3 | -6640 |
| TFRC | -6637 |
| KIF5A | -6634 |
| TBC1D4 | -6633 |
| GAPVD1 | -6615 |
| SURF4 | -6593 |
| TRAPPC10 | -6585 |
| MON1B | -6563 |
| LMAN2 | -6558 |
| CHMP4C | -6557 |
| RALA | -6548 |
| WASL | -6543 |
| IGF2R | -6540 |
| HPS1 | -6536 |
| DNM2 | -6535 |
| COPB2 | -6532 |
| HSPH1 | -6524 |
| CD55 | -6517 |
| PPP6R1 | -6511 |
| ARCN1 | -6505 |
| TMED9 | -6502 |
| APP | -6492 |
| MAN1A2 | -6460 |
| CLTA | -6439 |
| M6PR | -6416 |
| SLC2A8 | -6375 |
| FNBP1 | -6371 |
| KIF3B | -6315 |
| TBC1D10B | -6270 |
| SEC24C | -6236 |
| CLTC | -6220 |
| TBC1D20 | -6203 |
| RAB3IL1 | -6158 |
| GGA2 | -6138 |
| REPS2 | -6121 |
| TMED10 | -6116 |
| ARPC4 | -6094 |
| CLTB | -6064 |
| MASP1 | -6062 |
| ARF1 | -6021 |
| AMBP | -6015 |
| RAB9A | -6014 |
| COLEC11 | -5996 |
| SEC16A | -5971 |
| COPE | -5961 |
| COG3 | -5948 |
| NAPA | -5921 |
| KDELR2 | -5893 |
| KIF2A | -5815 |
| ARF4 | -5812 |
| RAB7A | -5810 |
| SYS1 | -5789 |
| SEC31A | -5766 |
| GOLIM4 | -5729 |
| CSNK1D | -5722 |
| CBL | -5708 |
| ACBD3 | -5703 |
| SNAP23 | -5681 |
| OPTN | -5656 |
| TBC1D17 | -5587 |
| CYTH2 | -5571 |
| MADD | -5505 |
| SEC24B | -5475 |
| KIF16B | -5457 |
| KIF5B | -5426 |
| GOLGA5 | -5424 |
| FTH1 | -5419 |
| RAB5A | -5408 |
| PLIN3 | -5406 |
| ARF6 | -5404 |
| TXNDC5 | -5385 |
| EGFR | -5383 |
| CLINT1 | -5368 |
| TFG | -5336 |
| GOLGA2 | -5310 |
| STX5 | -5300 |
| ACTR3 | -5296 |
| KIF13B | -5291 |
| RAB32 | -5287 |
| RAB35 | -5270 |
| PPP6C | -5241 |
| TMF1 | -5205 |
| ACTR1A | -5162 |
| COPS2 | -5161 |
| TBC1D16 | -5152 |
| RAB3GAP1 | -5143 |
| COPG1 | -5135 |
| CYTH1 | -5123 |
| KDELR1 | -5094 |
| VAMP2 | -5088 |
| UBA52 | -5068 |
| ULK1 | -5025 |
| TSC1 | -5024 |
| CHMP4B | -5021 |
| GBF1 | -4981 |
| POLG | -4973 |
| VAMP8 | -4969 |
| SPTBN1 | -4901 |
| YKT6 | -4899 |
| COPS8 | -4894 |
| RAB31 | -4876 |
| CAPZA1 | -4855 |
| AREG | -4847 |
| NSF | -4839 |
| ARFGAP3 | -4817 |
| TJP1 | -4801 |
| SH3D19 | -4772 |
| MYH9 | -4726 |
| YIPF6 | -4714 |
| VPS37B | -4696 |
| ANK1 | -4656 |
| HSPA8 | -4654 |
| RABEP1 | -4653 |
| GOLGA4 | -4624 |
| VPS37C | -4620 |
| COPS3 | -4618 |
| AP2M1 | -4603 |
| ARL1 | -4579 |
| TRAPPC2L | -4576 |
| VPS53 | -4557 |
| NAA35 | -4552 |
| TGFA | -4511 |
| CYTH3 | -4502 |
| AGPAT3 | -4469 |
| CTSC | -4446 |
| HBEGF | -4402 |
| TRAPPC12 | -4380 |
| TBC1D25 | -4373 |
| VPS51 | -4345 |
| VPS45 | -4271 |
| GAK | -4264 |
| UBB | -4263 |
| COG2 | -4254 |
| HGS | -4210 |
| AP1S2 | -4204 |
| SH3GL1 | -4200 |
| RAB3IP | -4190 |
| VPS37A | -4187 |
| SFN | -4169 |
| AP3S1 | -4104 |
| COPB1 | -4098 |
| TMED3 | -4057 |
| ZW10 | -4054 |
| DNAJC6 | -4039 |
| TRAPPC3 | -4032 |
| GCC1 | -4030 |
| TRAPPC8 | -4019 |
| DENND5B | -4010 |
| COG5 | -3964 |
| KIF9 | -3960 |
| COPA | -3958 |
| DCTN2 | -3957 |
| SYNJ1 | -3952 |
| SCARB1 | -3949 |
| DNASE2 | -3925 |
| EXOC3 | -3898 |
| DYNC1LI2 | -3897 |
| NAPG | -3872 |
| SNAPIN | -3828 |
| NAA30 | -3779 |
| AGFG1 | -3713 |
| APOE | -3670 |
| TBC1D15 | -3653 |
| KIF21A | -3640 |
| DCTN5 | -3634 |
| MVB12B | -3629 |
| DYNC1H1 | -3614 |
| PACSIN2 | -3606 |
| YWHAH | -3511 |
| USO1 | -3509 |
| GPS1 | -3506 |
| MYO5A | -3500 |
| AP2A2 | -3499 |
| GOLGB1 | -3498 |
| RAB1B | -3479 |
| LMAN1 | -3431 |
| LMAN2L | -3429 |
| GRK3 | -3418 |
| DENND1A | -3391 |
| SBF1 | -3389 |
| KLC2 | -3375 |
| GABARAP | -3322 |
| RAB1A | -3307 |
| SYT11 | -3281 |
| ARRB2 | -3248 |
| CD59 | -3245 |
| PIP5K1C | -3229 |
| KIFC2 | -3159 |
| RALGAPA2 | -3147 |
| RAB5C | -3129 |
| LNPEP | -3128 |
| DENND5A | -3083 |
| TBC1D2 | -3081 |
| COPS6 | -3063 |
| PRKAA2 | -3053 |
| SCARB2 | -3052 |
| GRB2 | -3047 |
| COPS5 | -3031 |
| HBA1 | -3024 |
| RAB33B | -2981 |
| SAR1B | -2973 |
| BLOC1S3 | -2972 |
| APOB | -2964 |
| AKT1 | -2958 |
| AP2S1 | -2922 |
| VPS54 | -2824 |
| VAMP7 | -2787 |
| DYNC1I2 | -2780 |
| RPS27A | -2773 |
| TOR1A | -2741 |
| SEC23A | -2717 |
| LRP1 | -2699 |
| RIC1 | -2565 |
| GABARAPL2 | -2535 |
| DYNC1LI1 | -2519 |
| PUM1 | -2507 |
| TSC2 | -2462 |
| ARF3 | -2430 |
| ARFIP2 | -2367 |
| MAN2A2 | -2336 |
| RAB8A | -2247 |
| MON1A | -2216 |
| ARPC2 | -2209 |
| KIF1C | -2167 |
| RAB4A | -2148 |
| TSG101 | -2130 |
| TGOLN2 | -2105 |
| TOR1B | -2030 |
| GDI2 | -2026 |
| CNIH3 | -1958 |
| AKT2 | -1946 |
| DCTN4 | -1937 |
| AP1G1 | -1916 |
| TBC1D10A | -1914 |
| AP2A1 | -1902 |
| UBAP1 | -1894 |
| RAB39B | -1774 |
| PRKAB2 | -1763 |
| DENND4C | -1727 |
| CHMP5 | -1722 |
| SEC22C | -1684 |
| CUX1 | -1665 |
| DCTN1 | -1635 |
| BIN1 | -1622 |
| SYNJ2 | -1613 |
| ARFGAP1 | -1587 |
| CCZ1 | -1551 |
| CAPZA2 | -1549 |
| ARPC5 | -1511 |
| STX18 | -1499 |
| DTNBP1 | -1483 |
| AP4E1 | -1454 |
| RALGAPB | -1446 |
| SNX9 | -1443 |
| BICD2 | -1420 |
| KIF26B | -1395 |
| NAA38 | -1234 |
| MYO1C | -1212 |
| SNF8 | -1198 |
| SBF2 | -1186 |
| CAPZB | -1169 |
| CHMP2A | -1088 |
| MAN2A1 | -1040 |
| HSP90AA1 | -1030 |
| MAN1A1 | -1021 |
| YWHAG | -1018 |
| TRIP11 | -990 |
| FCHO2 | -984 |
| VPS4B | -934 |
| SH3KBP1 | -917 |
| BLOC1S1 | -915 |
| DVL2 | -905 |
| RGP1 | -894 |
| YWHAZ | -885 |
| CHMP2B | -878 |
| RAB11B | -876 |
| COPS7B | -839 |
| GALNT1 | -816 |
| EXOC2 | -747 |
| AP1S3 | -739 |
| EPN1 | -737 |
| SNAP29 | -703 |
| VAMP3 | -698 |
| PRKAB1 | -680 |
| KIFC1 | -657 |
| CALM1 | -655 |
| CCZ1B | -629 |
| PPP6R3 | -623 |
| GCC2 | -597 |
| ITSN2 | -546 |
| AP4B1 | -526 |
| STX4 | -491 |
| PAFAH1B2 | -471 |
| NAPB | -419 |
| RAB18 | -372 |
| DCTN6 | -318 |
| STX6 | -263 |
| PIK3C2A | -176 |
| GDI1 | -158 |
| PAFAH1B1 | -118 |
| EXOC8 | -92 |
| SCARF1 | -89 |
| GOLGA1 | -86 |
| COPS4 | -28 |
| AP3B1 | 13 |
| STON2 | 17 |
| RAC1 | 44 |
| RABGAP1 | 98 |
| TBC1D3 | 112 |
| YWHAE | 129 |
| ITSN1 | 159 |
| CNIH1 | 212 |
| TRAPPC5 | 239 |
| TBC1D14 | 280 |
| RAB30 | 288 |
| PAFAH1B3 | 289 |
| ANK3 | 303 |
| EXOC5 | 337 |
| PRKAG2 | 375 |
| SEC23IP | 390 |
| BET1 | 457 |
| SCFD1 | 485 |
| SORT1 | 504 |
| COLEC12 | 522 |
| YWHAQ | 542 |
| NEDD8 | 580 |
| GOSR1 | 621 |
| FCHO1 | 665 |
| RAB3GAP2 | 730 |
| F8 | 735 |
| UBC | 779 |
| COPZ1 | 782 |
| VPS37D | 809 |
| F5 | 831 |
| SEC22B | 859 |
| CHMP4A | 909 |
| AP1M2 | 914 |
| GJC1 | 937 |
| AP1B1 | 940 |
| RAB12 | 950 |
| KDELR3 | 976 |
| CTTN | 982 |
| SLC2A4 | 1030 |
| EXOC4 | 1053 |
| DENND4B | 1143 |
| COL1A1 | 1188 |
| KIF27 | 1204 |
| GRK2 | 1205 |
| FNBP1L | 1226 |
| TPD52 | 1228 |
| CHMP3 | 1229 |
| LDLRAP1 | 1234 |
| GOSR2 | 1238 |
| HIP1R | 1249 |
| EPS15 | 1254 |
| ARFGAP2 | 1283 |
| RAB6A | 1296 |
| DAB2 | 1366 |
| RAB6B | 1396 |
| ACTR2 | 1435 |
| PREB | 1446 |
| DCTN3 | 1457 |
| RIN3 | 1485 |
| KIF6 | 1507 |
| SPARC | 1607 |
| RAB10 | 1625 |
| VTA1 | 1653 |
| NECAP2 | 1733 |
| CHML | 1746 |
| TRAPPC4 | 1781 |
| DENND1B | 1843 |
| KIF3C | 1853 |
| TRAPPC13 | 1878 |
| GORASP1 | 1903 |
| COG4 | 1972 |
| PICALM | 2021 |
| AP2B1 | 2029 |
| YWHAB | 2082 |
| DENND4A | 2123 |
| SNX5 | 2153 |
| AGTR1 | 2260 |
| KIF5C | 2266 |
| TBC1D13 | 2281 |
| ALS2 | 2318 |
| STX10 | 2338 |
| VPS4A | 2374 |
| HPS4 | 2384 |
| SPTAN1 | 2385 |
| STON1 | 2425 |
| NBAS | 2435 |
| UBQLN2 | 2456 |
| VPS36 | 2474 |
| EXOC6 | 2506 |
| DYNLL1 | 2509 |
| BNIP1 | 2517 |
| GGA1 | 2520 |
| BLOC1S4 | 2530 |
| TRAPPC6B | 2584 |
| STX17 | 2586 |
| STX16 | 2644 |
| MYO6 | 2665 |
| CHMP7 | 2690 |
| RAB21 | 2694 |
| KIF1B | 2782 |
| USE1 | 2847 |
| VPS25 | 2895 |
| RAB5B | 2913 |
| KIF21B | 2922 |
| AP1M1 | 2926 |
| RINT1 | 2930 |
| RAB27A | 3011 |
| ARPC1A | 3022 |
| MAN1C1 | 3072 |
| STAM2 | 3080 |
| TRAPPC1 | 3089 |
| REPS1 | 3092 |
| ALB | 3096 |
| DENND2A | 3098 |
| KLC3 | 3105 |
| AP4M1 | 3223 |
| VAMP4 | 3226 |
| TPD52L1 | 3255 |
| AP1G2 | 3257 |
| COG6 | 3264 |
| KIF3A | 3299 |
| SEC22A | 3312 |
| STAB1 | 3437 |
| EREG | 3467 |
| EPS15L1 | 3478 |
| BET1L | 3487 |
| EXOC7 | 3531 |
| TRAPPC2 | 3547 |
| RAB14 | 3647 |
| RAB13 | 3724 |
| ST5 | 3764 |
| BLOC1S6 | 3795 |
| ARPC3 | 3797 |
| PRKAG1 | 3836 |
| SPTBN2 | 3883 |
| STXBP3 | 3896 |
| KLC4 | 3897 |
| TBC1D24 | 3937 |
| TBC1D7 | 3939 |
| DENND2C | 3943 |
| SRC | 3962 |
| SERPINA1 | 4014 |
| SCOC | 4060 |
| TBC1D1 | 4089 |
| RIN1 | 4122 |
| VPS52 | 4124 |
| ANKRD28 | 4146 |
| VPS28 | 4152 |
| GGA3 | 4199 |
| RAB3A | 4309 |
| TRIP10 | 4417 |
| RAB11A | 4527 |
| COG1 | 4586 |
| KLC1 | 4611 |
| RAB8B | 4676 |
| ASPSCR1 | 4685 |
| ARF5 | 4743 |
| COG7 | 4792 |
| DENND6B | 4871 |
| KIF18B | 4885 |
| APOL1 | 4896 |
| RAB36 | 4950 |
| AP4S1 | 4973 |
| TRAPPC9 | 5033 |
| SYTL1 | 5101 |
| STAM | 5109 |
| RINL | 5161 |
| LDLR | 5216 |
| KIF18A | 5234 |
| CD36 | 5264 |
| SNX18 | 5273 |
| NECAP1 | 5336 |
| PACSIN3 | 5360 |
| COL7A1 | 5362 |
| TBC1D10C | 5382 |
| CHM | 5425 |
| CENPE | 5538 |
| ACTR10 | 5570 |
| MVB12A | 5589 |
| BICD1 | 5599 |
| COPS7A | 5653 |
| DENND1C | 5679 |
| DENND6A | 5729 |
| TBC1D8B | 5738 |
| RACGAP1 | 5789 |
| AP1S1 | 5804 |
| TF | 5850 |
| HPX | 5880 |
| CHMP6 | 5904 |
| KIF20A | 5931 |
| KIF2C | 5981 |
| KIF15 | 6037 |
| DYNLL2 | 6044 |
| KIF4A | 6056 |
| CD4 | 6074 |
| PLA2G6 | 6084 |
| RIN2 | 6115 |
| UBQLN1 | 6140 |
| COPG2 | 6142 |
| KIF12 | 6210 |
| TRAPPC11 | 6281 |
| GJC2 | 6283 |
| ARFRP1 | 6299 |
| EXOC1 | 6302 |
| KIF23 | 6313 |
| RABEPK | 6388 |
| CLTCL1 | 6404 |
| DNM1 | 6505 |
| FZD4 | 6534 |
| HPR | 6549 |
| KIFAP3 | 6573 |
| KIF11 | 6577 |
| GALNT2 | 6578 |
| DENND3 | 6588 |
| C2CD5 | 6602 |
| GJB1 | 6678 |
| KIF20B | 6682 |
| HP | 6732 |
| SEC16B | 6744 |
| COG8 | 6745 |
| OCRL | 6835 |
| EPN2 | 6839 |
| CPD | 6859 |
| KIF22 | 6933 |
| APOA1 | 6993 |
| TRAPPC6A | 7244 |
| HIP1 | 7319 |
Signaling by Receptor Tyrosine Kinases
| 1146 | |
|---|---|
| set | Signaling by Receptor Tyrosine Kinases |
| setSize | 405 |
| pANOVA | 7.81e-10 |
| s.dist | -0.179 |
| p.adjustANOVA | 2.76e-08 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| ATP6V0B | -7064 |
| PGF | -7053 |
| SHB | -7035 |
| ATP6V0A1 | -6979 |
| BCAR1 | -6926 |
| ATP6V1D | -6922 |
| SHC1 | -6910 |
| ATP6V0D1 | -6908 |
| ATP6V0A2 | -6880 |
| MET | -6878 |
| RANBP9 | -6871 |
| VGF | -6864 |
| HNRNPM | -6829 |
| PDGFRB | -6820 |
| TRIB3 | -6798 |
| PTPN3 | -6738 |
| HNRNPF | -6735 |
| FURIN | -6683 |
| FOSL1 | -6672 |
| ATP6V0E1 | -6622 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ATP6V0B | -7064 |
| PGF | -7053 |
| SHB | -7035 |
| ATP6V0A1 | -6979 |
| BCAR1 | -6926 |
| ATP6V1D | -6922 |
| SHC1 | -6910 |
| ATP6V0D1 | -6908 |
| ATP6V0A2 | -6880 |
| MET | -6878 |
| RANBP9 | -6871 |
| VGF | -6864 |
| HNRNPM | -6829 |
| PDGFRB | -6820 |
| TRIB3 | -6798 |
| PTPN3 | -6738 |
| HNRNPF | -6735 |
| FURIN | -6683 |
| FOSL1 | -6672 |
| ATP6V0E1 | -6622 |
| RAPGEF1 | -6586 |
| PRKCZ | -6584 |
| VEGFB | -6562 |
| RALA | -6548 |
| DUSP3 | -6541 |
| DNM2 | -6535 |
| EP300 | -6470 |
| MAPKAPK2 | -6461 |
| CLTA | -6439 |
| NAB2 | -6372 |
| LRIG1 | -6280 |
| ATP6V1E1 | -6271 |
| LCK | -6250 |
| ATP6AP1 | -6235 |
| CLTC | -6220 |
| ITGA2 | -6205 |
| PTPRK | -6199 |
| FGFR1 | -6191 |
| ATF2 | -6175 |
| PTPRJ | -6103 |
| FOSB | -6091 |
| ITCH | -6089 |
| ITPR3 | -6088 |
| MAP2K2 | -6087 |
| ATP6V0C | -6086 |
| KIDINS220 | -6056 |
| PTBP1 | -6035 |
| MEF2D | -5995 |
| RRAD | -5988 |
| DUSP4 | -5977 |
| MAPKAP1 | -5936 |
| ATP6V1C2 | -5929 |
| SIN3A | -5884 |
| SPP1 | -5872 |
| MEMO1 | -5843 |
| ADAM17 | -5836 |
| DIAPH1 | -5806 |
| MAPKAPK3 | -5773 |
| ELK1 | -5733 |
| WASF1 | -5712 |
| CBL | -5708 |
| STAT1 | -5668 |
| CRK | -5650 |
| PRKCD | -5638 |
| ATP6V1B2 | -5574 |
| CTNNA1 | -5558 |
| HRAS | -5543 |
| MAPK12 | -5538 |
| PRKCE | -5510 |
| GRB10 | -5504 |
| SHC2 | -5479 |
| POLR2L | -5471 |
| SOCS6 | -5467 |
| IRS2 | -5461 |
| NCF2 | -5438 |
| BRK1 | -5431 |
| ARF6 | -5404 |
| EGFR | -5383 |
| ATP6V1G1 | -5352 |
| PTPN12 | -5326 |
| LAMA3 | -5316 |
| NRP2 | -5313 |
| PDE3B | -5303 |
| RIT1 | -5298 |
| RHOA | -5294 |
| POLR2F | -5283 |
| PIK3C3 | -5220 |
| CDC37 | -5178 |
| FOS | -5174 |
| PPP2CA | -5168 |
| MXD4 | -5116 |
| INSR | -5097 |
| AAMP | -5076 |
| PDGFC | -5072 |
| UBA52 | -5068 |
| MAPK1 | -5066 |
| PAK2 | -4957 |
| ATP6V1C1 | -4946 |
| PSEN1 | -4938 |
| ATF1 | -4925 |
| NOS3 | -4903 |
| AREG | -4847 |
| CHD4 | -4830 |
| SH2B3 | -4752 |
| BRAF | -4749 |
| PPP2R1A | -4744 |
| MST1 | -4720 |
| POLR2E | -4667 |
| VAV3 | -4642 |
| AP2M1 | -4603 |
| PPP2CB | -4523 |
| TGFA | -4511 |
| ABI1 | -4478 |
| VEGFA | -4456 |
| TIAL1 | -4432 |
| ATP6V1H | -4423 |
| HBEGF | -4402 |
| MAPK7 | -4382 |
| PIK3R1 | -4376 |
| NCOR1 | -4374 |
| PTK2 | -4346 |
| ITPR1 | -4321 |
| ITGAV | -4312 |
| UBB | -4263 |
| HGS | -4210 |
| SH3GL1 | -4200 |
| HIF1A | -4165 |
| ITGB1 | -4145 |
| GAB2 | -4127 |
| MAP2K1 | -4120 |
| CSK | -4113 |
| FGF17 | -4015 |
| GRB7 | -4006 |
| SPINT1 | -3991 |
| EGR3 | -3972 |
| NCK2 | -3916 |
| TNS3 | -3893 |
| TAB2 | -3878 |
| DUSP7 | -3870 |
| RPS6KA1 | -3857 |
| PTPN2 | -3809 |
| KLB | -3807 |
| FRS2 | -3790 |
| SHC3 | -3782 |
| ATP6V1A | -3777 |
| FGFRL1 | -3751 |
| TNS4 | -3726 |
| POLR2B | -3699 |
| MTOR | -3683 |
| APOE | -3670 |
| ROCK1 | -3594 |
| POLR2H | -3593 |
| JUNB | -3526 |
| AP2A2 | -3499 |
| GRAP | -3478 |
| POLR2C | -3425 |
| DUSP6 | -3376 |
| WASF2 | -3366 |
| HSPB1 | -3343 |
| MEF2A | -3308 |
| GALNT3 | -3227 |
| EGR2 | -3207 |
| TCF12 | -3164 |
| SPHK1 | -3142 |
| GTF2F1 | -3103 |
| SRF | -3090 |
| ANOS1 | -3087 |
| GRB2 | -3047 |
| LYN | -3038 |
| RPS6KA3 | -3030 |
| AKT1 | -2958 |
| AP2S1 | -2922 |
| ARHGEF7 | -2913 |
| SPRED2 | -2862 |
| USP8 | -2820 |
| PIK3CA | -2813 |
| FGFR4 | -2795 |
| NCKAP1 | -2788 |
| ELMO1 | -2779 |
| RPS27A | -2773 |
| ROCK2 | -2772 |
| IGF1R | -2746 |
| JAK2 | -2719 |
| HDAC1 | -2676 |
| ADAM10 | -2671 |
| PDGFA | -2660 |
| AXL | -2605 |
| PIK3CB | -2588 |
| ARC | -2587 |
| SPRED1 | -2574 |
| PSEN2 | -2559 |
| MAP2K5 | -2441 |
| TLR9 | -2371 |
| ESRP2 | -2361 |
| MKNK1 | -2340 |
| PSENEN | -2327 |
| ERBIN | -2316 |
| NELFB | -2298 |
| PIK3R3 | -2279 |
| CDC42 | -2172 |
| NCBP1 | -2151 |
| RAB4A | -2148 |
| PPP2R5D | -2117 |
| PRR5 | -2094 |
| RICTOR | -2076 |
| KRAS | -2044 |
| SPRY2 | -1990 |
| AKT2 | -1946 |
| SPRY1 | -1918 |
| AP2A1 | -1902 |
| MAPK13 | -1875 |
| HNRNPA1 | -1795 |
| ITGA3 | -1662 |
| STAT6 | -1541 |
| WWOX | -1477 |
| EGR1 | -1475 |
| PRKACB | -1429 |
| ADAP1 | -1403 |
| PIK3R2 | -1355 |
| CDK5 | -1352 |
| RANBP10 | -1342 |
| YES1 | -1340 |
| LAMC1 | -1300 |
| VRK3 | -1278 |
| CUL5 | -1229 |
| ABI2 | -1197 |
| FGFR3 | -1195 |
| RPS6KA2 | -1149 |
| HSP90AA1 | -1030 |
| MUC20 | -1019 |
| NCKAP1L | -972 |
| SOS1 | -950 |
| SH3KBP1 | -917 |
| ATP6V1F | -868 |
| PTPN11 | -867 |
| WWP1 | -779 |
| EPN1 | -737 |
| LAMB3 | -673 |
| CALM1 | -655 |
| BAIAP2 | -637 |
| SPINT2 | -632 |
| POLR2J | -603 |
| REST | -593 |
| NCSTN | -554 |
| ATP6V1E2 | -534 |
| GABRG3 | -451 |
| HDAC2 | -338 |
| ID2 | -282 |
| LAMC2 | -228 |
| CDK5R1 | -157 |
| HDAC3 | 38 |
| RAC1 | 44 |
| KITLG | 92 |
| TCIRG1 | 180 |
| NEDD4 | 196 |
| MAPK11 | 251 |
| RALB | 270 |
| RAP1A | 309 |
| FGF5 | 342 |
| PTPRS | 397 |
| PDPK1 | 399 |
| CREB1 | 474 |
| LAMB2 | 495 |
| CRKL | 524 |
| APH1A | 619 |
| ATP6V1G2 | 690 |
| LYL1 | 726 |
| ATP6V0D2 | 747 |
| NAB1 | 765 |
| UBC | 779 |
| LAMA4 | 790 |
| MATK | 851 |
| SGK1 | 865 |
| ELMO2 | 942 |
| PAK1 | 1031 |
| PIK3R4 | 1132 |
| SH2B2 | 1149 |
| GABRB3 | 1163 |
| LAMC3 | 1169 |
| EPS15 | 1254 |
| LAMA1 | 1285 |
| RBFOX2 | 1286 |
| GRIN2B | 1330 |
| NRP1 | 1353 |
| NCK1 | 1525 |
| GAB1 | 1575 |
| SPARC | 1607 |
| F3 | 1642 |
| PRKACA | 1736 |
| MLST8 | 1875 |
| MYC | 1892 |
| FYN | 1937 |
| CYFIP1 | 1939 |
| POLR2G | 2003 |
| AP2B1 | 2029 |
| YWHAB | 2082 |
| COL6A3 | 2085 |
| FGF23 | 2097 |
| FRS3 | 2112 |
| FLT4 | 2167 |
| YAP1 | 2171 |
| CYBA | 2202 |
| ID3 | 2220 |
| ITPR2 | 2257 |
| MAPK14 | 2269 |
| NRAS | 2310 |
| JUP | 2314 |
| POLR2D | 2418 |
| PRKCA | 2439 |
| PLCG1 | 2511 |
| THBS2 | 2512 |
| PXN | 2548 |
| GFAP | 2552 |
| RASA1 | 2559 |
| WASF3 | 2619 |
| STMN1 | 2680 |
| POLR2A | 2705 |
| PAG1 | 2774 |
| VAV2 | 2817 |
| GABRG2 | 2849 |
| STAM2 | 3080 |
| RPS6KA5 | 3086 |
| HNRNPH1 | 3111 |
| RAB4B | 3174 |
| COL6A2 | 3222 |
| CTNNB1 | 3272 |
| PTK6 | 3304 |
| STUB1 | 3373 |
| PCSK5 | 3449 |
| EREG | 3467 |
| EPS15L1 | 3478 |
| IRS1 | 3502 |
| FLRT1 | 3504 |
| DOCK1 | 3540 |
| RAP1B | 3577 |
| PTPN1 | 3622 |
| LAMB1 | 3783 |
| DOCK7 | 3822 |
| SRC | 3962 |
| FLRT2 | 3988 |
| GGA3 | 4199 |
| ERBB3 | 4249 |
| STAT3 | 4253 |
| CHEK1 | 4365 |
| FER | 4431 |
| PTPRU | 4441 |
| THBS3 | 4450 |
| TIAM1 | 4452 |
| ID1 | 4484 |
| ATP6V1B1 | 4549 |
| GTF2F2 | 4556 |
| JUND | 4563 |
| POLR2I | 4594 |
| PPP2R1B | 4614 |
| MDK | 4615 |
| RALGDS | 4617 |
| TPH1 | 4694 |
| BAX | 4757 |
| PLAT | 4797 |
| AHCYL1 | 4874 |
| SOCS1 | 5053 |
| DLG4 | 5108 |
| STAM | 5109 |
| MST1R | 5156 |
| STAT5A | 5288 |
| PCSK6 | 5326 |
| ADORA2A | 5330 |
| TRIB1 | 5404 |
| FES | 5506 |
| ERBB2 | 5534 |
| ATP6V0E2 | 5683 |
| SH2D2A | 5820 |
| TF | 5850 |
| POLR2K | 5962 |
| THBS1 | 5988 |
| FLT3LG | 6000 |
| THEM4 | 6080 |
| APH1B | 6168 |
| RNF41 | 6188 |
| CYFIP2 | 6224 |
| TIA1 | 6310 |
| DNM1 | 6505 |
| PTPN6 | 6557 |
| STAT5B | 6572 |
| DNAL4 | 6609 |
| LAMA5 | 6638 |
| MAPK3 | 6640 |
| COL4A5 | 6694 |
| HGFAC | 6708 |
| FGFBP3 | 6730 |
| PTK2B | 6809 |
| FGFR2 | 6811 |
| HPN | 6820 |
| NCBP2 | 6823 |
| PTPN18 | 6851 |
| PDGFB | 6920 |
| CTNND1 | 7129 |
| COL9A3 | 7151 |
| THBS4 | 7170 |
| FLRT3 | 7184 |
| COL6A1 | 7322 |
| JAK3 | 7326 |
| COL9A2 | 7348 |
| IGF2 | 7375 |
| PLG | 7380 |
Membrane Trafficking
| 614 | |
|---|---|
| set | Membrane Trafficking |
| setSize | 531 |
| pANOVA | 9.78e-10 |
| s.dist | -0.156 |
| p.adjustANOVA | 3.37e-08 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SEC24D | -7134 |
| RABGEF1 | -7111 |
| TMED2 | -7071 |
| MCFD2 | -7065 |
| ARRB1 | -7062 |
| MIA3 | -7049 |
| USP6NL | -7041 |
| MAP1LC3B | -7040 |
| AAK1 | -7032 |
| ANKRD27 | -6996 |
| RHOQ | -6969 |
| TMED7 | -6933 |
| VTI1A | -6899 |
| SEC24A | -6839 |
| GNS | -6813 |
| SEC13 | -6812 |
| ANK2 | -6778 |
| TMEM115 | -6764 |
| RAB43 | -6699 |
| FTL | -6697 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SEC24D | -7134 |
| RABGEF1 | -7111 |
| TMED2 | -7071 |
| MCFD2 | -7065 |
| ARRB1 | -7062 |
| MIA3 | -7049 |
| USP6NL | -7041 |
| MAP1LC3B | -7040 |
| AAK1 | -7032 |
| ANKRD27 | -6996 |
| RHOQ | -6969 |
| TMED7 | -6933 |
| VTI1A | -6899 |
| SEC24A | -6839 |
| GNS | -6813 |
| SEC13 | -6812 |
| ANK2 | -6778 |
| TMEM115 | -6764 |
| RAB43 | -6699 |
| FTL | -6697 |
| SNX2 | -6677 |
| RHOBTB3 | -6640 |
| TFRC | -6637 |
| KIF5A | -6634 |
| TBC1D4 | -6633 |
| GAPVD1 | -6615 |
| SURF4 | -6593 |
| TRAPPC10 | -6585 |
| MON1B | -6563 |
| LMAN2 | -6558 |
| CHMP4C | -6557 |
| RALA | -6548 |
| WASL | -6543 |
| IGF2R | -6540 |
| HPS1 | -6536 |
| DNM2 | -6535 |
| COPB2 | -6532 |
| CD55 | -6517 |
| PPP6R1 | -6511 |
| ARCN1 | -6505 |
| TMED9 | -6502 |
| APP | -6492 |
| MAN1A2 | -6460 |
| CLTA | -6439 |
| M6PR | -6416 |
| SLC2A8 | -6375 |
| FNBP1 | -6371 |
| KIF3B | -6315 |
| TBC1D10B | -6270 |
| SEC24C | -6236 |
| CLTC | -6220 |
| TBC1D20 | -6203 |
| RAB3IL1 | -6158 |
| GGA2 | -6138 |
| REPS2 | -6121 |
| TMED10 | -6116 |
| ARPC4 | -6094 |
| CLTB | -6064 |
| ARF1 | -6021 |
| RAB9A | -6014 |
| SEC16A | -5971 |
| COPE | -5961 |
| COG3 | -5948 |
| NAPA | -5921 |
| KDELR2 | -5893 |
| KIF2A | -5815 |
| ARF4 | -5812 |
| RAB7A | -5810 |
| SYS1 | -5789 |
| SEC31A | -5766 |
| GOLIM4 | -5729 |
| CSNK1D | -5722 |
| CBL | -5708 |
| ACBD3 | -5703 |
| SNAP23 | -5681 |
| OPTN | -5656 |
| TBC1D17 | -5587 |
| CYTH2 | -5571 |
| MADD | -5505 |
| SEC24B | -5475 |
| KIF16B | -5457 |
| KIF5B | -5426 |
| GOLGA5 | -5424 |
| FTH1 | -5419 |
| RAB5A | -5408 |
| PLIN3 | -5406 |
| ARF6 | -5404 |
| TXNDC5 | -5385 |
| EGFR | -5383 |
| CLINT1 | -5368 |
| TFG | -5336 |
| GOLGA2 | -5310 |
| STX5 | -5300 |
| ACTR3 | -5296 |
| KIF13B | -5291 |
| RAB32 | -5287 |
| RAB35 | -5270 |
| PPP6C | -5241 |
| TMF1 | -5205 |
| ACTR1A | -5162 |
| COPS2 | -5161 |
| TBC1D16 | -5152 |
| RAB3GAP1 | -5143 |
| COPG1 | -5135 |
| CYTH1 | -5123 |
| KDELR1 | -5094 |
| VAMP2 | -5088 |
| UBA52 | -5068 |
| ULK1 | -5025 |
| TSC1 | -5024 |
| CHMP4B | -5021 |
| GBF1 | -4981 |
| POLG | -4973 |
| VAMP8 | -4969 |
| SPTBN1 | -4901 |
| YKT6 | -4899 |
| COPS8 | -4894 |
| RAB31 | -4876 |
| CAPZA1 | -4855 |
| AREG | -4847 |
| NSF | -4839 |
| ARFGAP3 | -4817 |
| TJP1 | -4801 |
| SH3D19 | -4772 |
| MYH9 | -4726 |
| YIPF6 | -4714 |
| VPS37B | -4696 |
| ANK1 | -4656 |
| HSPA8 | -4654 |
| RABEP1 | -4653 |
| GOLGA4 | -4624 |
| VPS37C | -4620 |
| COPS3 | -4618 |
| AP2M1 | -4603 |
| ARL1 | -4579 |
| TRAPPC2L | -4576 |
| VPS53 | -4557 |
| NAA35 | -4552 |
| TGFA | -4511 |
| CYTH3 | -4502 |
| AGPAT3 | -4469 |
| CTSC | -4446 |
| HBEGF | -4402 |
| TRAPPC12 | -4380 |
| TBC1D25 | -4373 |
| VPS51 | -4345 |
| VPS45 | -4271 |
| GAK | -4264 |
| UBB | -4263 |
| COG2 | -4254 |
| HGS | -4210 |
| AP1S2 | -4204 |
| SH3GL1 | -4200 |
| RAB3IP | -4190 |
| VPS37A | -4187 |
| SFN | -4169 |
| AP3S1 | -4104 |
| COPB1 | -4098 |
| TMED3 | -4057 |
| ZW10 | -4054 |
| DNAJC6 | -4039 |
| TRAPPC3 | -4032 |
| GCC1 | -4030 |
| TRAPPC8 | -4019 |
| DENND5B | -4010 |
| COG5 | -3964 |
| KIF9 | -3960 |
| COPA | -3958 |
| DCTN2 | -3957 |
| SYNJ1 | -3952 |
| DNASE2 | -3925 |
| EXOC3 | -3898 |
| DYNC1LI2 | -3897 |
| NAPG | -3872 |
| SNAPIN | -3828 |
| NAA30 | -3779 |
| AGFG1 | -3713 |
| TBC1D15 | -3653 |
| KIF21A | -3640 |
| DCTN5 | -3634 |
| MVB12B | -3629 |
| DYNC1H1 | -3614 |
| PACSIN2 | -3606 |
| YWHAH | -3511 |
| USO1 | -3509 |
| GPS1 | -3506 |
| MYO5A | -3500 |
| AP2A2 | -3499 |
| GOLGB1 | -3498 |
| RAB1B | -3479 |
| LMAN1 | -3431 |
| LMAN2L | -3429 |
| GRK3 | -3418 |
| DENND1A | -3391 |
| SBF1 | -3389 |
| KLC2 | -3375 |
| GABARAP | -3322 |
| RAB1A | -3307 |
| SYT11 | -3281 |
| ARRB2 | -3248 |
| CD59 | -3245 |
| PIP5K1C | -3229 |
| KIFC2 | -3159 |
| RALGAPA2 | -3147 |
| RAB5C | -3129 |
| LNPEP | -3128 |
| DENND5A | -3083 |
| TBC1D2 | -3081 |
| COPS6 | -3063 |
| PRKAA2 | -3053 |
| SCARB2 | -3052 |
| GRB2 | -3047 |
| COPS5 | -3031 |
| RAB33B | -2981 |
| SAR1B | -2973 |
| BLOC1S3 | -2972 |
| APOB | -2964 |
| AKT1 | -2958 |
| AP2S1 | -2922 |
| VPS54 | -2824 |
| VAMP7 | -2787 |
| DYNC1I2 | -2780 |
| RPS27A | -2773 |
| TOR1A | -2741 |
| SEC23A | -2717 |
| RIC1 | -2565 |
| GABARAPL2 | -2535 |
| DYNC1LI1 | -2519 |
| PUM1 | -2507 |
| TSC2 | -2462 |
| ARF3 | -2430 |
| ARFIP2 | -2367 |
| MAN2A2 | -2336 |
| RAB8A | -2247 |
| MON1A | -2216 |
| ARPC2 | -2209 |
| KIF1C | -2167 |
| RAB4A | -2148 |
| TSG101 | -2130 |
| TGOLN2 | -2105 |
| TOR1B | -2030 |
| GDI2 | -2026 |
| CNIH3 | -1958 |
| AKT2 | -1946 |
| DCTN4 | -1937 |
| AP1G1 | -1916 |
| TBC1D10A | -1914 |
| AP2A1 | -1902 |
| UBAP1 | -1894 |
| RAB39B | -1774 |
| PRKAB2 | -1763 |
| DENND4C | -1727 |
| CHMP5 | -1722 |
| SEC22C | -1684 |
| CUX1 | -1665 |
| DCTN1 | -1635 |
| BIN1 | -1622 |
| SYNJ2 | -1613 |
| ARFGAP1 | -1587 |
| CCZ1 | -1551 |
| CAPZA2 | -1549 |
| ARPC5 | -1511 |
| STX18 | -1499 |
| DTNBP1 | -1483 |
| AP4E1 | -1454 |
| RALGAPB | -1446 |
| SNX9 | -1443 |
| BICD2 | -1420 |
| KIF26B | -1395 |
| NAA38 | -1234 |
| MYO1C | -1212 |
| SNF8 | -1198 |
| SBF2 | -1186 |
| CAPZB | -1169 |
| CHMP2A | -1088 |
| MAN2A1 | -1040 |
| MAN1A1 | -1021 |
| YWHAG | -1018 |
| TRIP11 | -990 |
| FCHO2 | -984 |
| VPS4B | -934 |
| SH3KBP1 | -917 |
| BLOC1S1 | -915 |
| DVL2 | -905 |
| RGP1 | -894 |
| YWHAZ | -885 |
| CHMP2B | -878 |
| RAB11B | -876 |
| COPS7B | -839 |
| GALNT1 | -816 |
| EXOC2 | -747 |
| AP1S3 | -739 |
| EPN1 | -737 |
| SNAP29 | -703 |
| VAMP3 | -698 |
| PRKAB1 | -680 |
| KIFC1 | -657 |
| CALM1 | -655 |
| CCZ1B | -629 |
| PPP6R3 | -623 |
| GCC2 | -597 |
| ITSN2 | -546 |
| AP4B1 | -526 |
| STX4 | -491 |
| PAFAH1B2 | -471 |
| NAPB | -419 |
| RAB18 | -372 |
| DCTN6 | -318 |
| STX6 | -263 |
| PIK3C2A | -176 |
| GDI1 | -158 |
| PAFAH1B1 | -118 |
| EXOC8 | -92 |
| GOLGA1 | -86 |
| COPS4 | -28 |
| AP3B1 | 13 |
| STON2 | 17 |
| RAC1 | 44 |
| RABGAP1 | 98 |
| TBC1D3 | 112 |
| YWHAE | 129 |
| ITSN1 | 159 |
| CNIH1 | 212 |
| TRAPPC5 | 239 |
| TBC1D14 | 280 |
| RAB30 | 288 |
| PAFAH1B3 | 289 |
| ANK3 | 303 |
| EXOC5 | 337 |
| PRKAG2 | 375 |
| SEC23IP | 390 |
| BET1 | 457 |
| SCFD1 | 485 |
| SORT1 | 504 |
| YWHAQ | 542 |
| NEDD8 | 580 |
| GOSR1 | 621 |
| FCHO1 | 665 |
| RAB3GAP2 | 730 |
| F8 | 735 |
| UBC | 779 |
| COPZ1 | 782 |
| VPS37D | 809 |
| F5 | 831 |
| SEC22B | 859 |
| CHMP4A | 909 |
| AP1M2 | 914 |
| GJC1 | 937 |
| AP1B1 | 940 |
| RAB12 | 950 |
| KDELR3 | 976 |
| CTTN | 982 |
| SLC2A4 | 1030 |
| EXOC4 | 1053 |
| DENND4B | 1143 |
| KIF27 | 1204 |
| GRK2 | 1205 |
| FNBP1L | 1226 |
| TPD52 | 1228 |
| CHMP3 | 1229 |
| LDLRAP1 | 1234 |
| GOSR2 | 1238 |
| HIP1R | 1249 |
| EPS15 | 1254 |
| ARFGAP2 | 1283 |
| RAB6A | 1296 |
| DAB2 | 1366 |
| RAB6B | 1396 |
| ACTR2 | 1435 |
| PREB | 1446 |
| DCTN3 | 1457 |
| RIN3 | 1485 |
| KIF6 | 1507 |
| RAB10 | 1625 |
| VTA1 | 1653 |
| NECAP2 | 1733 |
| CHML | 1746 |
| TRAPPC4 | 1781 |
| DENND1B | 1843 |
| KIF3C | 1853 |
| TRAPPC13 | 1878 |
| GORASP1 | 1903 |
| COG4 | 1972 |
| PICALM | 2021 |
| AP2B1 | 2029 |
| YWHAB | 2082 |
| DENND4A | 2123 |
| SNX5 | 2153 |
| AGTR1 | 2260 |
| KIF5C | 2266 |
| TBC1D13 | 2281 |
| ALS2 | 2318 |
| STX10 | 2338 |
| VPS4A | 2374 |
| HPS4 | 2384 |
| SPTAN1 | 2385 |
| STON1 | 2425 |
| NBAS | 2435 |
| UBQLN2 | 2456 |
| VPS36 | 2474 |
| EXOC6 | 2506 |
| DYNLL1 | 2509 |
| BNIP1 | 2517 |
| GGA1 | 2520 |
| BLOC1S4 | 2530 |
| TRAPPC6B | 2584 |
| STX17 | 2586 |
| STX16 | 2644 |
| MYO6 | 2665 |
| CHMP7 | 2690 |
| RAB21 | 2694 |
| KIF1B | 2782 |
| USE1 | 2847 |
| VPS25 | 2895 |
| RAB5B | 2913 |
| KIF21B | 2922 |
| AP1M1 | 2926 |
| RINT1 | 2930 |
| RAB27A | 3011 |
| ARPC1A | 3022 |
| MAN1C1 | 3072 |
| STAM2 | 3080 |
| TRAPPC1 | 3089 |
| REPS1 | 3092 |
| DENND2A | 3098 |
| KLC3 | 3105 |
| AP4M1 | 3223 |
| VAMP4 | 3226 |
| TPD52L1 | 3255 |
| AP1G2 | 3257 |
| COG6 | 3264 |
| KIF3A | 3299 |
| SEC22A | 3312 |
| EREG | 3467 |
| EPS15L1 | 3478 |
| BET1L | 3487 |
| EXOC7 | 3531 |
| TRAPPC2 | 3547 |
| RAB14 | 3647 |
| RAB13 | 3724 |
| ST5 | 3764 |
| BLOC1S6 | 3795 |
| ARPC3 | 3797 |
| PRKAG1 | 3836 |
| SPTBN2 | 3883 |
| STXBP3 | 3896 |
| KLC4 | 3897 |
| TBC1D24 | 3937 |
| TBC1D7 | 3939 |
| DENND2C | 3943 |
| SRC | 3962 |
| SERPINA1 | 4014 |
| SCOC | 4060 |
| TBC1D1 | 4089 |
| RIN1 | 4122 |
| VPS52 | 4124 |
| ANKRD28 | 4146 |
| VPS28 | 4152 |
| GGA3 | 4199 |
| RAB3A | 4309 |
| TRIP10 | 4417 |
| RAB11A | 4527 |
| COG1 | 4586 |
| KLC1 | 4611 |
| RAB8B | 4676 |
| ASPSCR1 | 4685 |
| ARF5 | 4743 |
| COG7 | 4792 |
| DENND6B | 4871 |
| KIF18B | 4885 |
| RAB36 | 4950 |
| AP4S1 | 4973 |
| TRAPPC9 | 5033 |
| SYTL1 | 5101 |
| STAM | 5109 |
| RINL | 5161 |
| LDLR | 5216 |
| KIF18A | 5234 |
| SNX18 | 5273 |
| NECAP1 | 5336 |
| PACSIN3 | 5360 |
| COL7A1 | 5362 |
| TBC1D10C | 5382 |
| CHM | 5425 |
| CENPE | 5538 |
| ACTR10 | 5570 |
| MVB12A | 5589 |
| BICD1 | 5599 |
| COPS7A | 5653 |
| DENND1C | 5679 |
| DENND6A | 5729 |
| TBC1D8B | 5738 |
| RACGAP1 | 5789 |
| AP1S1 | 5804 |
| TF | 5850 |
| CHMP6 | 5904 |
| KIF20A | 5931 |
| KIF2C | 5981 |
| KIF15 | 6037 |
| DYNLL2 | 6044 |
| KIF4A | 6056 |
| CD4 | 6074 |
| PLA2G6 | 6084 |
| RIN2 | 6115 |
| UBQLN1 | 6140 |
| COPG2 | 6142 |
| KIF12 | 6210 |
| TRAPPC11 | 6281 |
| GJC2 | 6283 |
| ARFRP1 | 6299 |
| EXOC1 | 6302 |
| KIF23 | 6313 |
| RABEPK | 6388 |
| CLTCL1 | 6404 |
| DNM1 | 6505 |
| FZD4 | 6534 |
| KIFAP3 | 6573 |
| KIF11 | 6577 |
| GALNT2 | 6578 |
| DENND3 | 6588 |
| C2CD5 | 6602 |
| GJB1 | 6678 |
| KIF20B | 6682 |
| SEC16B | 6744 |
| COG8 | 6745 |
| OCRL | 6835 |
| EPN2 | 6839 |
| CPD | 6859 |
| KIF22 | 6933 |
| TRAPPC6A | 7244 |
| HIP1 | 7319 |
Selenocysteine synthesis
| 1057 | |
|---|---|
| set | Selenocysteine synthesis |
| setSize | 89 |
| pANOVA | 1e-09 |
| s.dist | -0.375 |
| p.adjustANOVA | 3.37e-08 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| SEPHS2 | -6447 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| RPL30 | -4081 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| SEPHS2 | -6447 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| RPL30 | -4081 |
| RPS9 | -4028 |
| RPL18 | -3961 |
| RPL26L1 | -3873 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| RPL28 | -3546 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| RPS15A | -3019 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| RPS27A | -2773 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| RPL23 | -1913 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| PSTK | -1545 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| RPS25 | -937 |
| RPL13 | -706 |
| RPL5 | -495 |
| SECISBP2 | -410 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| RPL9 | 261 |
| RPL31 | 330 |
| RPS26 | 419 |
| RPL21 | 1385 |
| RPL22 | 2142 |
| RPL36A | 2875 |
| EEFSEC | 3653 |
| SEPSECS | 6852 |
IRE1alpha activates chaperones
| 498 | |
|---|---|
| set | IRE1alpha activates chaperones |
| setSize | 50 |
| pANOVA | 2.24e-09 |
| s.dist | -0.489 |
| p.adjustANOVA | 7.35e-08 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| HSPA5 | -7144 |
| DNAJB11 | -7141 |
| HYOU1 | -7140 |
| DNAJC3 | -7131 |
| DNAJB9 | -7125 |
| SYVN1 | -7108 |
| PDIA6 | -7106 |
| EDEM1 | -7103 |
| WFS1 | -7096 |
| GFPT1 | -7051 |
| MYDGF | -6976 |
| SERP1 | -6964 |
| WIPI1 | -6942 |
| SHC1 | -6910 |
| ATP6V0D1 | -6908 |
| SSR1 | -6907 |
| FKBP14 | -6896 |
| SRPRB | -6893 |
| ERN1 | -6872 |
| TSPYL2 | -6784 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HSPA5 | -7144 |
| DNAJB11 | -7141 |
| HYOU1 | -7140 |
| DNAJC3 | -7131 |
| DNAJB9 | -7125 |
| SYVN1 | -7108 |
| PDIA6 | -7106 |
| EDEM1 | -7103 |
| WFS1 | -7096 |
| GFPT1 | -7051 |
| MYDGF | -6976 |
| SERP1 | -6964 |
| WIPI1 | -6942 |
| SHC1 | -6910 |
| ATP6V0D1 | -6908 |
| SSR1 | -6907 |
| FKBP14 | -6896 |
| SRPRB | -6893 |
| ERN1 | -6872 |
| TSPYL2 | -6784 |
| HDGF | -6715 |
| TATDN2 | -6467 |
| TPP1 | -6407 |
| TLN1 | -6146 |
| CXXC1 | -6033 |
| ADD1 | -5966 |
| SEC31A | -5766 |
| PPP2R5B | -5131 |
| SRPRA | -4802 |
| CTDSP2 | -4462 |
| KLHDC3 | -3802 |
| LMNA | -3717 |
| GSK3A | -3684 |
| ZBTB17 | -3194 |
| DCTN1 | -1635 |
| ARFGAP1 | -1587 |
| YIF1A | 195 |
| PDIA5 | 579 |
| KDELR3 | 976 |
| SULT1A3 | 1040 |
| GOSR2 | 1238 |
| PREB | 1446 |
| EXTL2 | 3353 |
| EXTL3 | 3575 |
| ACADVL | 4157 |
| CUL7 | 4377 |
| PLA2G4B | 4716 |
| XBP1 | 5937 |
| DDX11 | 6254 |
| EXTL1 | 6941 |
Transport to the Golgi and subsequent modification
| 1306 | |
|---|---|
| set | Transport to the Golgi and subsequent modification |
| setSize | 146 |
| pANOVA | 2.45e-09 |
| s.dist | -0.286 |
| p.adjustANOVA | 7.84e-08 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SEC24D | -7134 |
| TMED2 | -7071 |
| MCFD2 | -7065 |
| MIA3 | -7049 |
| FUT3 | -7001 |
| TMED7 | -6933 |
| SEC24A | -6839 |
| SEC13 | -6812 |
| ST3GAL4 | -6801 |
| ANK2 | -6778 |
| TMEM115 | -6764 |
| TRAPPC10 | -6585 |
| LMAN2 | -6558 |
| COPB2 | -6532 |
| CD55 | -6517 |
| PPP6R1 | -6511 |
| ARCN1 | -6505 |
| TMED9 | -6502 |
| MAN1A2 | -6460 |
| MGAT1 | -6401 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SEC24D | -7134 |
| TMED2 | -7071 |
| MCFD2 | -7065 |
| MIA3 | -7049 |
| FUT3 | -7001 |
| TMED7 | -6933 |
| SEC24A | -6839 |
| SEC13 | -6812 |
| ST3GAL4 | -6801 |
| ANK2 | -6778 |
| TMEM115 | -6764 |
| TRAPPC10 | -6585 |
| LMAN2 | -6558 |
| COPB2 | -6532 |
| CD55 | -6517 |
| PPP6R1 | -6511 |
| ARCN1 | -6505 |
| TMED9 | -6502 |
| MAN1A2 | -6460 |
| MGAT1 | -6401 |
| MGAT4B | -6279 |
| SEC24C | -6236 |
| TBC1D20 | -6203 |
| TMED10 | -6116 |
| ARF1 | -6021 |
| SEC16A | -5971 |
| COPE | -5961 |
| COG3 | -5948 |
| NAPA | -5921 |
| KDELR2 | -5893 |
| MGAT5 | -5854 |
| ARF4 | -5812 |
| SEC31A | -5766 |
| CSNK1D | -5722 |
| SEC24B | -5475 |
| TFG | -5336 |
| GOLGA2 | -5310 |
| STX5 | -5300 |
| PPP6C | -5241 |
| ACTR1A | -5162 |
| COPG1 | -5135 |
| FUT8 | -5134 |
| KDELR1 | -5094 |
| MGAT4A | -5018 |
| GBF1 | -4981 |
| SPTBN1 | -4901 |
| YKT6 | -4899 |
| CAPZA1 | -4855 |
| B4GALT3 | -4852 |
| AREG | -4847 |
| NSF | -4839 |
| ARFGAP3 | -4817 |
| ANK1 | -4656 |
| TRAPPC2L | -4576 |
| TGFA | -4511 |
| CTSC | -4446 |
| COG2 | -4254 |
| COPB1 | -4098 |
| TMED3 | -4057 |
| TRAPPC3 | -4032 |
| COG5 | -3964 |
| COPA | -3958 |
| DCTN2 | -3957 |
| DYNC1LI2 | -3897 |
| NAPG | -3872 |
| DCTN5 | -3634 |
| DYNC1H1 | -3614 |
| USO1 | -3509 |
| GOLGB1 | -3498 |
| RAB1B | -3479 |
| LMAN1 | -3431 |
| LMAN2L | -3429 |
| MGAT2 | -3327 |
| RAB1A | -3307 |
| CD59 | -3245 |
| SAR1B | -2973 |
| DYNC1I2 | -2780 |
| SEC23A | -2717 |
| DYNC1LI1 | -2519 |
| B4GALT2 | -2487 |
| ARF3 | -2430 |
| MAN2A2 | -2336 |
| CNIH3 | -1958 |
| DCTN4 | -1937 |
| ST6GAL1 | -1828 |
| SEC22C | -1684 |
| DCTN1 | -1635 |
| ARFGAP1 | -1587 |
| CAPZA2 | -1549 |
| CAPZB | -1169 |
| MAN2A1 | -1040 |
| MAN1A1 | -1021 |
| PPP6R3 | -623 |
| NAPB | -419 |
| DCTN6 | -318 |
| B4GALT1 | -262 |
| CNIH1 | 212 |
| TRAPPC5 | 239 |
| ANK3 | 303 |
| SEC23IP | 390 |
| BET1 | 457 |
| SCFD1 | 485 |
| GOSR1 | 621 |
| F8 | 735 |
| COPZ1 | 782 |
| F5 | 831 |
| SEC22B | 859 |
| KDELR3 | 976 |
| GOSR2 | 1238 |
| ARFGAP2 | 1283 |
| PREB | 1446 |
| DCTN3 | 1457 |
| MGAT4C | 1714 |
| TRAPPC4 | 1781 |
| GORASP1 | 1903 |
| COG4 | 1972 |
| SPTAN1 | 2385 |
| DYNLL1 | 2509 |
| TRAPPC6B | 2584 |
| STX17 | 2586 |
| B4GALT4 | 2602 |
| FUCA1 | 2696 |
| B4GALT6 | 2881 |
| MAN1C1 | 3072 |
| TRAPPC1 | 3089 |
| COG6 | 3264 |
| SEC22A | 3312 |
| BET1L | 3487 |
| TRAPPC2 | 3547 |
| SPTBN2 | 3883 |
| SERPINA1 | 4014 |
| ANKRD28 | 4146 |
| MANEA | 4202 |
| COG1 | 4586 |
| ARF5 | 4743 |
| COG7 | 4792 |
| TRAPPC9 | 5033 |
| COL7A1 | 5362 |
| ACTR10 | 5570 |
| DYNLL2 | 6044 |
| COPG2 | 6142 |
| SEC16B | 6744 |
| COG8 | 6745 |
| B4GALT5 | 6846 |
| CHST10 | 6919 |
| TRAPPC6A | 7244 |
DNA strand elongation
| 230 | |
|---|---|
| set | DNA strand elongation |
| setSize | 32 |
| pANOVA | 3.66e-09 |
| s.dist | 0.602 |
| p.adjustANOVA | 1.15e-07 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| GINS1 | 7335 |
| MCM5 | 6983 |
| PRIM1 | 6962 |
| RPA2 | 6961 |
| GINS2 | 6909 |
| MCM6 | 6787 |
| GINS3 | 6759 |
| MCM2 | 6755 |
| POLA2 | 6695 |
| MCM4 | 6635 |
| PRIM2 | 6599 |
| GINS4 | 6560 |
| PCNA | 6523 |
| RPA3 | 6375 |
| LIG1 | 6206 |
| POLD1 | 5832 |
| RFC3 | 5349 |
| POLA1 | 4949 |
| POLD2 | 4930 |
| MCM3 | 4773 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| GINS1 | 7335 |
| MCM5 | 6983 |
| PRIM1 | 6962 |
| RPA2 | 6961 |
| GINS2 | 6909 |
| MCM6 | 6787 |
| GINS3 | 6759 |
| MCM2 | 6755 |
| POLA2 | 6695 |
| MCM4 | 6635 |
| PRIM2 | 6599 |
| GINS4 | 6560 |
| PCNA | 6523 |
| RPA3 | 6375 |
| LIG1 | 6206 |
| POLD1 | 5832 |
| RFC3 | 5349 |
| POLA1 | 4949 |
| POLD2 | 4930 |
| MCM3 | 4773 |
| RFC4 | 4683 |
| MCM8 | 4587 |
| POLD3 | 4459 |
| RFC5 | 4385 |
| RFC2 | 3878 |
| DNA2 | 3379 |
| MCM7 | 2514 |
| CDC45 | 1783 |
| FEN1 | 367 |
| POLD4 | -3285 |
| RFC1 | -4980 |
| RPA1 | -5008 |
PIP3 activates AKT signaling
| 768 | |
|---|---|
| set | PIP3 activates AKT signaling |
| setSize | 223 |
| pANOVA | 6.57e-09 |
| s.dist | -0.226 |
| p.adjustANOVA | 2.01e-07 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RRAGC | -7009 |
| PIK3AP1 | -6957 |
| MET | -6878 |
| PDGFRB | -6820 |
| TRIB3 | -6798 |
| RRAGD | -6743 |
| PSMF1 | -6663 |
| PSME4 | -6450 |
| PSMD2 | -6435 |
| PIP4K2C | -6335 |
| LCK | -6250 |
| FGFR1 | -6191 |
| ATF2 | -6175 |
| BAD | -6118 |
| AKT1S1 | -5990 |
| PSMD6 | -5951 |
| MAPKAP1 | -5936 |
| AGO3 | -5803 |
| PSMA2 | -5801 |
| PPP2R5A | -5740 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RRAGC | -7009 |
| PIK3AP1 | -6957 |
| MET | -6878 |
| PDGFRB | -6820 |
| TRIB3 | -6798 |
| RRAGD | -6743 |
| PSMF1 | -6663 |
| PSME4 | -6450 |
| PSMD2 | -6435 |
| PIP4K2C | -6335 |
| LCK | -6250 |
| FGFR1 | -6191 |
| ATF2 | -6175 |
| BAD | -6118 |
| AKT1S1 | -5990 |
| PSMD6 | -5951 |
| MAPKAP1 | -5936 |
| AGO3 | -5803 |
| PSMA2 | -5801 |
| PPP2R5A | -5740 |
| PSMA1 | -5730 |
| MAF1 | -5705 |
| MKRN1 | -5695 |
| EZH2 | -5631 |
| MTA2 | -5619 |
| PSMC1 | -5564 |
| SLC38A9 | -5539 |
| PSMD3 | -5535 |
| AGO2 | -5530 |
| PIP4K2A | -5495 |
| PSME2 | -5481 |
| IRS2 | -5461 |
| EGFR | -5383 |
| STRN | -5363 |
| PSMD1 | -5351 |
| LAMTOR5 | -5293 |
| CASP9 | -5247 |
| PPP2CA | -5168 |
| WWP2 | -5151 |
| PPP2R5B | -5131 |
| PTENP1 | -5107 |
| GSK3B | -5101 |
| INSR | -5097 |
| UBA52 | -5068 |
| MAPK1 | -5066 |
| CSNK2A1 | -5040 |
| PHLPP1 | -5029 |
| VAPA | -4898 |
| PSMB6 | -4888 |
| PSMC6 | -4878 |
| AREG | -4847 |
| TRIM27 | -4835 |
| CHD4 | -4830 |
| RRAGB | -4819 |
| PSMC4 | -4808 |
| TNRC6C | -4805 |
| TNKS | -4790 |
| PIK3CD | -4759 |
| PPP2R1A | -4744 |
| PTEN | -4721 |
| SNAI1 | -4674 |
| PSMD9 | -4638 |
| CSNK2A2 | -4546 |
| MBD3 | -4543 |
| PPP2CB | -4523 |
| TGFA | -4511 |
| HBEGF | -4402 |
| PIK3R1 | -4376 |
| PSMB7 | -4372 |
| CBX8 | -4370 |
| PHC1 | -4280 |
| UBB | -4263 |
| ATN1 | -4249 |
| TNRC6B | -4212 |
| PSMA4 | -4211 |
| BMI1 | -4180 |
| GAB2 | -4127 |
| GATAD2A | -4108 |
| PSMC5 | -4091 |
| CBX4 | -4063 |
| HDAC5 | -4034 |
| FGF17 | -4015 |
| PHLPP2 | -3934 |
| RPS6KB2 | -3901 |
| PSME3 | -3813 |
| KLB | -3807 |
| FRS2 | -3790 |
| RHEB | -3762 |
| GSK3A | -3684 |
| MTOR | -3683 |
| CDKN1A | -3580 |
| RCOR1 | -3493 |
| CHUK | -3364 |
| RBBP4 | -3297 |
| PIP5K1C | -3229 |
| TNKS2 | -3213 |
| PPARG | -3168 |
| SEM1 | -3130 |
| PSMA3 | -3078 |
| GRB2 | -3047 |
| AKT1 | -2958 |
| JUN | -2934 |
| XIAP | -2929 |
| PSMD8 | -2928 |
| PIK3CA | -2813 |
| FGFR4 | -2795 |
| RPS27A | -2773 |
| RHOG | -2756 |
| PSMA5 | -2715 |
| HDAC1 | -2676 |
| PDGFA | -2660 |
| LAMTOR3 | -2631 |
| PIK3CB | -2588 |
| PSMD13 | -2577 |
| TSC2 | -2462 |
| PSMC2 | -2389 |
| PSME1 | -2348 |
| OTUD3 | -2342 |
| PIK3R3 | -2279 |
| IRAK1 | -2218 |
| PPP2R5D | -2117 |
| PRR5 | -2094 |
| FOXO4 | -2077 |
| RICTOR | -2076 |
| TP53 | -2020 |
| AKT2 | -1946 |
| PSMB3 | -1915 |
| PIP5K1A | -1831 |
| PSMC3 | -1509 |
| EGR1 | -1475 |
| PIK3R2 | -1355 |
| CHD3 | -1321 |
| FGFR3 | -1195 |
| PSMB4 | -1144 |
| GATAD2B | -1092 |
| MDM2 | -956 |
| PSMA7 | -892 |
| PTPN11 | -867 |
| CDKN1B | -786 |
| LAMTOR1 | -774 |
| PSMB5 | -742 |
| REST | -593 |
| CD19 | -472 |
| PSMD11 | -432 |
| HDAC2 | -338 |
| LAMTOR2 | -148 |
| PSMA6 | -126 |
| HDAC3 | 38 |
| RAC1 | 44 |
| KITLG | 92 |
| HDAC7 | 130 |
| USP7 | 134 |
| NEDD4 | 196 |
| PPP2R5E | 283 |
| FGF5 | 342 |
| SUZ12 | 346 |
| IL1RL1 | 347 |
| PDPK1 | 399 |
| RPTOR | 407 |
| PSMB10 | 423 |
| CREB1 | 474 |
| FRK | 602 |
| UBC | 779 |
| RNF146 | 825 |
| PHC3 | 843 |
| PIP5K1B | 1047 |
| PML | 1051 |
| PSMB1 | 1054 |
| GAB1 | 1575 |
| IRAK4 | 1591 |
| TRAF6 | 1597 |
| MTA1 | 1810 |
| TNRC6A | 1824 |
| LAMTOR4 | 1834 |
| MLST8 | 1875 |
| PSMB2 | 1876 |
| FYN | 1937 |
| FGF23 | 2097 |
| FOXO3 | 2282 |
| EED | 2369 |
| RNF2 | 2454 |
| RRAGA | 2609 |
| PIP4K2B | 2639 |
| PPP2R5C | 2743 |
| CBX6 | 2911 |
| ESR2 | 3316 |
| STUB1 | 3373 |
| EREG | 3467 |
| IRS1 | 3502 |
| NR4A1 | 3691 |
| PHC2 | 3713 |
| SRC | 3962 |
| RING1 | 4067 |
| KDM1A | 4224 |
| ERBB3 | 4249 |
| PSMD12 | 4303 |
| AGO1 | 4307 |
| CSNK2B | 4415 |
| PSMD4 | 4567 |
| PPP2R1B | 4614 |
| PSMD10 | 4933 |
| PSMD7 | 4942 |
| PSMD5 | 5116 |
| RBBP7 | 5134 |
| IL1RAP | 5361 |
| FOXO1 | 5418 |
| PSMB9 | 5491 |
| ERBB2 | 5534 |
| CNOT6L | 5623 |
| MYD88 | 5939 |
| PSMD14 | 5974 |
| FLT3LG | 6000 |
| USP13 | 6054 |
| THEM4 | 6080 |
| MOV10 | 6408 |
| MTA3 | 6411 |
| AGO4 | 6581 |
| MAPK3 | 6640 |
| SCMH1 | 6656 |
| FGFR2 | 6811 |
| PDGFB | 6920 |
| SALL4 | 6934 |
| CBX2 | 6958 |
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
| 673 | |
|---|---|
| set | N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
| setSize | 34 |
| pANOVA | 7.03e-09 |
| s.dist | -0.574 |
| p.adjustANOVA | 2.11e-07 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CALR | -7142 |
| SEL1L | -7124 |
| SYVN1 | -7108 |
| EDEM1 | -7103 |
| CANX | -7092 |
| PDIA3 | -7086 |
| DERL2 | -7046 |
| OS9 | -6986 |
| UGGT1 | -6954 |
| MLEC | -6902 |
| VCP | -6720 |
| RNF5 | -6629 |
| DERL1 | -6423 |
| RNF185 | -6359 |
| RNF103 | -6135 |
| PRKCSH | -5934 |
| PSMC1 | -5564 |
| EDEM2 | -5520 |
| UBXN1 | -5450 |
| UBA52 | -5068 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CALR | -7142 |
| SEL1L | -7124 |
| SYVN1 | -7108 |
| EDEM1 | -7103 |
| CANX | -7092 |
| PDIA3 | -7086 |
| DERL2 | -7046 |
| OS9 | -6986 |
| UGGT1 | -6954 |
| MLEC | -6902 |
| VCP | -6720 |
| RNF5 | -6629 |
| DERL1 | -6423 |
| RNF185 | -6359 |
| RNF103 | -6135 |
| PRKCSH | -5934 |
| PSMC1 | -5564 |
| EDEM2 | -5520 |
| UBXN1 | -5450 |
| UBA52 | -5068 |
| UBB | -4263 |
| MAN1B1 | -3561 |
| RNF139 | -3064 |
| NGLY1 | -2909 |
| RPS27A | -2773 |
| AMFR | -2698 |
| MOGS | -2275 |
| EDEM3 | -1903 |
| UBC | 779 |
| UGGT2 | 1425 |
| TRIM13 | 1883 |
| GANAB | 2813 |
| RAD23B | 3141 |
| ENGASE | 6457 |
Innate Immune System
| 520 | |
|---|---|
| set | Innate Immune System |
| setSize | 740 |
| pANOVA | 9.58e-09 |
| s.dist | -0.125 |
| p.adjustANOVA | 2.81e-07 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| DNAJC3 | -7131 |
| HSP90B1 | -7129 |
| PLPP5 | -7074 |
| ATP6V0B | -7064 |
| MAP3K8 | -7060 |
| MAGT1 | -7045 |
| CNN2 | -7036 |
| ERP44 | -7023 |
| LAMP1 | -6982 |
| ATP6V0A1 | -6979 |
| CEACAM1 | -6974 |
| LAMP2 | -6966 |
| CTSL | -6951 |
| ARSB | -6939 |
| GGH | -6936 |
| CCR6 | -6932 |
| LGALS3 | -6923 |
| ATP6V1D | -6922 |
| SHC1 | -6910 |
| ATP6V0D1 | -6908 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| DNAJC3 | -7131 |
| HSP90B1 | -7129 |
| PLPP5 | -7074 |
| ATP6V0B | -7064 |
| MAP3K8 | -7060 |
| MAGT1 | -7045 |
| CNN2 | -7036 |
| ERP44 | -7023 |
| LAMP1 | -6982 |
| ATP6V0A1 | -6979 |
| CEACAM1 | -6974 |
| LAMP2 | -6966 |
| CTSL | -6951 |
| ARSB | -6939 |
| GGH | -6936 |
| CCR6 | -6932 |
| LGALS3 | -6923 |
| ATP6V1D | -6922 |
| SHC1 | -6910 |
| ATP6V0D1 | -6908 |
| MLEC | -6902 |
| ATP6V0A2 | -6880 |
| S100A11 | -6865 |
| P2RX1 | -6853 |
| BRI3 | -6843 |
| ACTG1 | -6841 |
| GNS | -6813 |
| PNP | -6810 |
| NDUFC2 | -6804 |
| C4BPB | -6787 |
| CYSTM1 | -6768 |
| NEU1 | -6752 |
| NFATC3 | -6750 |
| VCP | -6720 |
| IRAK2 | -6713 |
| FTL | -6697 |
| PYGB | -6693 |
| PSMF1 | -6663 |
| ASAH1 | -6648 |
| ATP6V0E1 | -6622 |
| SURF4 | -6593 |
| TOLLIP | -6576 |
| NF2 | -6559 |
| WASL | -6543 |
| DUSP3 | -6541 |
| IGF2R | -6540 |
| FUCA2 | -6538 |
| DNM2 | -6535 |
| DNAJC5 | -6522 |
| CD55 | -6517 |
| TMBIM1 | -6493 |
| APP | -6492 |
| NFKBIB | -6474 |
| EP300 | -6470 |
| ALDOA | -6463 |
| MAPKAPK2 | -6461 |
| HEXB | -6455 |
| CLEC10A | -6451 |
| PSME4 | -6450 |
| DDX3X | -6449 |
| ICAM3 | -6441 |
| NFKBIA | -6437 |
| PSMD2 | -6435 |
| DDOST | -6429 |
| CDK13 | -6415 |
| KCMF1 | -6393 |
| KPNB1 | -6379 |
| BCL2L1 | -6349 |
| UBR4 | -6345 |
| ATAD3B | -6334 |
| GALNS | -6314 |
| CTSA | -6288 |
| TAX1BP1 | -6281 |
| ATP6V1E1 | -6271 |
| PRDX4 | -6268 |
| LCK | -6250 |
| MAP3K1 | -6230 |
| NPC2 | -6207 |
| ATF2 | -6175 |
| PGAM1 | -6174 |
| RAP2B | -6173 |
| TMC6 | -6114 |
| CD63 | -6107 |
| PTPRJ | -6103 |
| PDXK | -6100 |
| ARPC4 | -6094 |
| ITCH | -6089 |
| ITPR3 | -6088 |
| ATP6V0C | -6086 |
| CYLD | -6066 |
| MASP1 | -6062 |
| DEGS1 | -6054 |
| MALT1 | -6026 |
| COLEC11 | -5996 |
| DUSP4 | -5977 |
| PSMD6 | -5951 |
| IKBKG | -5946 |
| OTUD5 | -5944 |
| SRP14 | -5938 |
| MVP | -5935 |
| PRKCSH | -5934 |
| ATP6V1C2 | -5929 |
| CCT2 | -5926 |
| BPIFB6 | -5923 |
| ARL8A | -5922 |
| MYO9B | -5920 |
| DDX41 | -5919 |
| DOK3 | -5877 |
| CAPN1 | -5850 |
| ECSIT | -5840 |
| ANO6 | -5826 |
| RAB7A | -5810 |
| DIAPH1 | -5806 |
| PSMA2 | -5801 |
| RIPK2 | -5779 |
| MAPKAPK3 | -5773 |
| CFL1 | -5737 |
| ELK1 | -5733 |
| PSMA1 | -5730 |
| WASF1 | -5712 |
| SNAP23 | -5681 |
| IQGAP1 | -5663 |
| CRK | -5650 |
| GLA | -5640 |
| PRKCD | -5638 |
| PANX1 | -5636 |
| POLR3E | -5626 |
| CCT8 | -5605 |
| ATP6V1B2 | -5574 |
| PSMC1 | -5564 |
| RAF1 | -5557 |
| CASP10 | -5555 |
| HRAS | -5543 |
| MAPK12 | -5538 |
| PSMD3 | -5535 |
| CDC34 | -5516 |
| PRKCE | -5510 |
| TRIM25 | -5492 |
| ISG15 | -5488 |
| PSME2 | -5481 |
| CD58 | -5480 |
| LRRFIP1 | -5477 |
| POLR2L | -5471 |
| IDH1 | -5470 |
| NCF2 | -5438 |
| BRK1 | -5431 |
| FTH1 | -5419 |
| TXNDC5 | -5385 |
| ATP6V1G1 | -5352 |
| PSMD1 | -5351 |
| IQGAP2 | -5323 |
| ACTR3 | -5296 |
| RHOA | -5294 |
| MYO10 | -5290 |
| POLR2F | -5283 |
| ILF2 | -5258 |
| CASP9 | -5247 |
| PELI1 | -5222 |
| PIK3C3 | -5220 |
| PSAP | -5218 |
| CTSB | -5204 |
| MIF | -5176 |
| FOS | -5174 |
| TBK1 | -5169 |
| PPP2CA | -5168 |
| PKM | -5137 |
| AAMP | -5076 |
| UBA52 | -5068 |
| MAPK1 | -5066 |
| ACTB | -5057 |
| EEF2 | -5049 |
| POLR1C | -4986 |
| VAMP8 | -4969 |
| BPIFB2 | -4967 |
| PAK2 | -4957 |
| CAB39 | -4956 |
| ATP6V1C1 | -4946 |
| PSEN1 | -4938 |
| ATF1 | -4925 |
| GPI | -4904 |
| NOS3 | -4903 |
| VAPA | -4898 |
| PSMB6 | -4888 |
| PSMC6 | -4878 |
| RAB31 | -4876 |
| CAPZA1 | -4855 |
| OSTF1 | -4843 |
| CTSK | -4821 |
| PSMC4 | -4808 |
| DSP | -4746 |
| PPP2R1A | -4744 |
| HMOX2 | -4742 |
| MYH9 | -4726 |
| GLIPR1 | -4691 |
| POLR2E | -4667 |
| UBE2V1 | -4655 |
| HSPA8 | -4654 |
| VAV3 | -4642 |
| FAF2 | -4640 |
| PSMD9 | -4638 |
| TSPAN14 | -4626 |
| TANK | -4621 |
| PGM1 | -4600 |
| NKIRAS2 | -4598 |
| OSCAR | -4571 |
| PPP2CB | -4523 |
| POLR1D | -4516 |
| MAP2K4 | -4505 |
| VAT1 | -4497 |
| ABI1 | -4478 |
| BCL10 | -4471 |
| CTSC | -4446 |
| PPIA | -4443 |
| ARPC1B | -4429 |
| HSP90AB1 | -4426 |
| ATP6V1H | -4423 |
| MAP2K7 | -4399 |
| MAPK7 | -4382 |
| PIK3R1 | -4376 |
| PSMB7 | -4372 |
| PTK2 | -4346 |
| UBE2M | -4337 |
| ITPR1 | -4321 |
| ITGAV | -4312 |
| UBB | -4263 |
| TRIM4 | -4229 |
| PLEKHO2 | -4227 |
| PSMA4 | -4211 |
| TOM1 | -4199 |
| ARG1 | -4179 |
| PPP3R1 | -4176 |
| YPEL5 | -4173 |
| XRCC5 | -4164 |
| EEF1A1 | -4138 |
| CUL1 | -4129 |
| GAB2 | -4127 |
| MAP2K1 | -4120 |
| DHX9 | -4112 |
| COPB1 | -4098 |
| LCN2 | -4096 |
| PSMC5 | -4091 |
| CAP1 | -4085 |
| PPP3CB | -4060 |
| UBE2D3 | -3997 |
| CNPY3 | -3981 |
| NME2 | -3974 |
| ORM1 | -3973 |
| SARM1 | -3956 |
| CKAP4 | -3939 |
| TIMP2 | -3938 |
| TTR | -3924 |
| CREBBP | -3888 |
| TAB2 | -3878 |
| DUSP7 | -3870 |
| RPS6KA1 | -3857 |
| PSME3 | -3813 |
| FBXW11 | -3784 |
| ATP6V1A | -3777 |
| HUWE1 | -3769 |
| PLCG2 | -3766 |
| CPNE1 | -3710 |
| LAT | -3697 |
| NLRC4 | -3690 |
| PDAP1 | -3657 |
| DYNC1H1 | -3614 |
| TXN | -3611 |
| ROCK1 | -3594 |
| POLR2H | -3593 |
| TMEM179B | -3567 |
| SIRPA | -3538 |
| COMMD9 | -3531 |
| NFKB1 | -3507 |
| MYO5A | -3500 |
| AP2A2 | -3499 |
| GOLGA7 | -3421 |
| DUSP6 | -3376 |
| WASF2 | -3366 |
| CHUK | -3364 |
| STBD1 | -3361 |
| HSPA6 | -3353 |
| MAP2K3 | -3342 |
| ATG12 | -3333 |
| MEF2A | -3308 |
| CD59 | -3245 |
| HEBP2 | -3167 |
| PA2G4 | -3141 |
| SEM1 | -3130 |
| RAB5C | -3129 |
| PSMA3 | -3078 |
| GRB2 | -3047 |
| LYN | -3038 |
| RPS6KA3 | -3030 |
| LAIR1 | -3025 |
| WIPF2 | -2965 |
| APOB | -2964 |
| PLAU | -2962 |
| TMEM30A | -2956 |
| JUN | -2934 |
| IKBKB | -2931 |
| PSMD8 | -2928 |
| RIPK1 | -2886 |
| STK11IP | -2838 |
| PIK3CA | -2813 |
| GRN | -2805 |
| TOMM70 | -2797 |
| NCKAP1 | -2788 |
| ELMO1 | -2779 |
| RPS27A | -2773 |
| EEA1 | -2764 |
| RHOG | -2756 |
| PSMA5 | -2715 |
| ADAM10 | -2671 |
| S100P | -2653 |
| RELA | -2632 |
| LAMTOR3 | -2631 |
| RHOF | -2600 |
| PIK3CB | -2588 |
| PSMD13 | -2577 |
| MAP3K14 | -2575 |
| B2M | -2523 |
| DYNC1LI1 | -2519 |
| POLR3H | -2496 |
| SERPINB6 | -2474 |
| ATP11B | -2420 |
| QPCT | -2416 |
| CANT1 | -2398 |
| PSMC2 | -2389 |
| TLR9 | -2371 |
| MAP2K6 | -2351 |
| PSME1 | -2348 |
| PRKDC | -2300 |
| PRCP | -2276 |
| POLR3B | -2273 |
| PTPN4 | -2238 |
| IRAK1 | -2218 |
| C8G | -2213 |
| ARPC2 | -2209 |
| CDC42 | -2172 |
| ARHGAP9 | -2170 |
| PPP2R5D | -2117 |
| CRISPLD2 | -2075 |
| KLRK1 | -2060 |
| AGER | -2057 |
| POLR3A | -2056 |
| KRAS | -2044 |
| GDI2 | -2026 |
| IST1 | -2001 |
| TICAM1 | -1956 |
| PSMB3 | -1915 |
| MAPK13 | -1875 |
| UNC13D | -1871 |
| PELI2 | -1870 |
| SDCBP | -1822 |
| IMPDH1 | -1807 |
| POLR3C | -1730 |
| CAND1 | -1658 |
| CAPZA2 | -1549 |
| STAT6 | -1541 |
| SLC2A3 | -1535 |
| MUC13 | -1524 |
| STOM | -1523 |
| ARPC5 | -1511 |
| PSMC3 | -1509 |
| PRKACB | -1429 |
| PIK3R2 | -1355 |
| YES1 | -1340 |
| LY96 | -1339 |
| TNIP2 | -1314 |
| NFKB2 | -1311 |
| VRK3 | -1278 |
| UBA3 | -1275 |
| QSOX1 | -1250 |
| ATP6AP2 | -1245 |
| ORM2 | -1240 |
| MYO1C | -1212 |
| ABI2 | -1197 |
| ADAM8 | -1193 |
| GYG1 | -1167 |
| RPS6KA2 | -1149 |
| PSMB4 | -1144 |
| ITK | -1112 |
| RAP2C | -1109 |
| HSP90AA1 | -1030 |
| MUC20 | -1019 |
| NCKAP1L | -972 |
| SOS1 | -950 |
| DDX58 | -927 |
| UBE2D2 | -913 |
| PSMA7 | -892 |
| COTL1 | -877 |
| ATP6V1F | -868 |
| PTPN11 | -867 |
| AMPD3 | -829 |
| GHDC | -827 |
| IKBKE | -787 |
| LAMTOR1 | -774 |
| PSMB5 | -742 |
| SNAP29 | -703 |
| RNASET2 | -701 |
| MAPK8 | -700 |
| DNAJC13 | -677 |
| CALM1 | -655 |
| BAIAP2 | -637 |
| MAN2B1 | -600 |
| TRAF2 | -577 |
| DHX36 | -566 |
| NCSTN | -554 |
| SKP1 | -544 |
| ATP6V1E2 | -534 |
| UNC93B1 | -517 |
| BIRC2 | -499 |
| CD19 | -472 |
| PAFAH1B2 | -471 |
| RELB | -469 |
| PSMD11 | -432 |
| RAB18 | -372 |
| TRAF3 | -356 |
| ADGRE5 | -313 |
| B4GALT1 | -262 |
| CMTM6 | -259 |
| PGRMC1 | -242 |
| GMFG | -220 |
| CASP4 | -184 |
| LAMTOR2 | -148 |
| PSMA6 | -126 |
| CPN2 | -110 |
| CRACR2A | -75 |
| PRDX6 | -54 |
| CREG1 | -47 |
| AHSG | 25 |
| XRCC6 | 28 |
| RAC1 | 44 |
| DGAT1 | 111 |
| RNF135 | 126 |
| NLRP1 | 136 |
| NKIRAS1 | 150 |
| TCIRG1 | 180 |
| MAPK11 | 251 |
| PGM2 | 263 |
| RAP1A | 309 |
| STK10 | 333 |
| FCER1G | 380 |
| PPP3CA | 381 |
| UBE2K | 383 |
| PDPK1 | 399 |
| PSMB10 | 423 |
| CREB1 | 474 |
| CCL22 | 584 |
| CYB5R3 | 600 |
| FRK | 602 |
| F2 | 635 |
| LAT2 | 670 |
| KCNAB2 | 675 |
| POLR3F | 688 |
| ATP6V1G2 | 690 |
| NOS1 | 709 |
| BST1 | 713 |
| ATP6V0D2 | 747 |
| CSTB | 776 |
| UBC | 779 |
| SLC27A2 | 829 |
| IRF3 | 862 |
| ELMO2 | 942 |
| PCBP2 | 974 |
| CRCP | 979 |
| NAPRT | 988 |
| LGMN | 1001 |
| PAK1 | 1031 |
| PSMB1 | 1054 |
| PECAM1 | 1098 |
| SIRPB1 | 1105 |
| TLR6 | 1131 |
| PIK3R4 | 1132 |
| PLD3 | 1239 |
| GUSB | 1260 |
| APAF1 | 1277 |
| RAB6A | 1296 |
| PPIE | 1333 |
| MOSPD2 | 1344 |
| BTRC | 1386 |
| ADGRG3 | 1417 |
| ACTR2 | 1435 |
| CXCR2 | 1464 |
| ATP11A | 1486 |
| GSN | 1496 |
| CTSS | 1499 |
| SIGIRR | 1500 |
| NCK1 | 1525 |
| POLR3G | 1545 |
| GLB1 | 1557 |
| LIMK1 | 1565 |
| IRAK4 | 1591 |
| TRAF6 | 1597 |
| RAB3D | 1600 |
| RAB10 | 1625 |
| SUGT1 | 1662 |
| HTN1 | 1687 |
| MAVS | 1695 |
| PRKACA | 1736 |
| MAPK9 | 1760 |
| SCAMP1 | 1817 |
| HSPA1A | 1835 |
| UBE2N | 1836 |
| HERC5 | 1855 |
| PSMB2 | 1876 |
| CLEC7A | 1881 |
| FADD | 1889 |
| ITGAX | 1919 |
| BCL2 | 1925 |
| FYN | 1937 |
| CYFIP1 | 1939 |
| PTPRN2 | 1971 |
| ABL1 | 2023 |
| ATP7A | 2111 |
| KLRD1 | 2155 |
| CTSV | 2161 |
| AGL | 2176 |
| SVIP | 2180 |
| SERPINB1 | 2181 |
| CYBA | 2202 |
| ITPR2 | 2257 |
| MAPK14 | 2269 |
| NRAS | 2310 |
| MGST1 | 2313 |
| JUP | 2314 |
| CARD9 | 2322 |
| SPTAN1 | 2385 |
| ARMC8 | 2401 |
| SLC15A4 | 2407 |
| MEFV | 2468 |
| HTN3 | 2502 |
| DYNLL1 | 2509 |
| PLCG1 | 2511 |
| PLAC8 | 2524 |
| TAB3 | 2566 |
| WASF3 | 2619 |
| CPPED1 | 2657 |
| FUCA1 | 2696 |
| HLA-B | 2764 |
| CTSD | 2812 |
| VAV2 | 2817 |
| BST2 | 2868 |
| ARSA | 2878 |
| RAB5B | 2913 |
| AP1M1 | 2926 |
| ATG5 | 2931 |
| MAPK10 | 2952 |
| RAB27A | 3011 |
| ARPC1A | 3022 |
| DTX4 | 3048 |
| PIN1 | 3074 |
| RPS6KA5 | 3086 |
| TRAPPC1 | 3089 |
| POLR3K | 3152 |
| CASP8 | 3157 |
| RAB4B | 3174 |
| SLC2A5 | 3250 |
| CTNNB1 | 3272 |
| CPNE3 | 3303 |
| TMEM63A | 3357 |
| DBNL | 3382 |
| PDZD11 | 3385 |
| APRT | 3389 |
| BIRC3 | 3477 |
| C5AR2 | 3489 |
| UBE2D1 | 3523 |
| SLC11A1 | 3527 |
| DOCK1 | 3540 |
| MANBA | 3572 |
| RAP1B | 3577 |
| TIFA | 3587 |
| PTGES2 | 3607 |
| RAB14 | 3647 |
| ATOX1 | 3659 |
| CST3 | 3732 |
| MAP3K7 | 3767 |
| ARPC3 | 3797 |
| LYZ | 3804 |
| DYNLT1 | 3809 |
| HVCN1 | 3884 |
| ACAA1 | 3886 |
| SRC | 3962 |
| SERPINA1 | 4014 |
| FABP5 | 4021 |
| RAB24 | 4024 |
| CPN1 | 4039 |
| PLD2 | 4048 |
| NBEAL2 | 4086 |
| MRE11 | 4100 |
| TRIM21 | 4105 |
| HLA-H | 4193 |
| CASP2 | 4204 |
| RNF216 | 4252 |
| C2 | 4264 |
| PSMD12 | 4303 |
| RAB3A | 4309 |
| CPB2 | 4337 |
| TNFAIP3 | 4359 |
| METTL7A | 4368 |
| SIKE1 | 4383 |
| VCL | 4407 |
| CSNK2B | 4415 |
| TIRAP | 4446 |
| POLR3D | 4454 |
| PLAUR | 4485 |
| PTAFR | 4486 |
| ATP6V1B1 | 4549 |
| ACLY | 4562 |
| PSMD4 | 4567 |
| HMOX1 | 4592 |
| DPP7 | 4601 |
| PPP2R1B | 4614 |
| ANPEP | 4690 |
| GAA | 4697 |
| APEH | 4698 |
| NFATC2 | 4720 |
| C7 | 4745 |
| AGPAT2 | 4769 |
| MUC15 | 4828 |
| AHCYL1 | 4874 |
| EPPIN | 4893 |
| PYGL | 4903 |
| IMPDH2 | 4910 |
| PSMD10 | 4933 |
| PSMD7 | 4942 |
| NLRC5 | 4976 |
| COMMD3 | 4983 |
| CAT | 5018 |
| PELI3 | 5019 |
| CD46 | 5036 |
| ORMDL3 | 5040 |
| ALPK1 | 5041 |
| SOCS1 | 5053 |
| PSMD5 | 5116 |
| TUBB | 5125 |
| LPCAT1 | 5166 |
| RBSN | 5208 |
| C4BPA | 5221 |
| CD36 | 5264 |
| GM2A | 5280 |
| DERA | 5319 |
| TBC1D10C | 5382 |
| GSDMD | 5413 |
| PFKL | 5437 |
| NOD1 | 5449 |
| ATG7 | 5453 |
| NCKIPSD | 5477 |
| PSMB9 | 5491 |
| HMGB1 | 5546 |
| VNN1 | 5548 |
| CFD | 5558 |
| ACTR10 | 5570 |
| NIT2 | 5596 |
| CLU | 5647 |
| CTSH | 5655 |
| SLCO4C1 | 5675 |
| ATP6V0E2 | 5683 |
| LBP | 5684 |
| MASP2 | 5751 |
| ACTR1B | 5765 |
| HLA-A | 5777 |
| CEP290 | 5787 |
| HGSNAT | 5921 |
| HLA-C | 5936 |
| MYD88 | 5939 |
| PSTPIP1 | 5948 |
| POLR2K | 5962 |
| ALDOC | 5970 |
| PSMD14 | 5974 |
| TRIM32 | 5977 |
| ATP8A1 | 5995 |
| PROS1 | 6053 |
| DHX58 | 6062 |
| CD4 | 6074 |
| PLA2G6 | 6084 |
| CD47 | 6101 |
| CASP1 | 6109 |
| C6orf120 | 6141 |
| AGA | 6147 |
| ANXA2 | 6155 |
| TRIM56 | 6183 |
| UBA7 | 6211 |
| CYFIP2 | 6224 |
| LTA4H | 6248 |
| DNASE1L1 | 6262 |
| NLRX1 | 6266 |
| ALAD | 6318 |
| ITGAL | 6325 |
| CD68 | 6463 |
| ITGB2 | 6494 |
| DNM1 | 6505 |
| BPIFB1 | 6516 |
| PTPN6 | 6557 |
| C6 | 6620 |
| MAPK3 | 6640 |
| IFIH1 | 6646 |
| TAB1 | 6687 |
| FGG | 6697 |
| SYNGR1 | 6711 |
| C5AR1 | 6719 |
| LRG1 | 6726 |
| HP | 6732 |
| CDA | 6735 |
| TUBB4B | 6758 |
| S100A1 | 6858 |
| ALDH3B1 | 6860 |
| ICAM2 | 6868 |
| SLC44A2 | 6879 |
| CFI | 6891 |
| PYCARD | 6900 |
| VTN | 6910 |
| MBL2 | 6911 |
| DSN1 | 6916 |
| RAB37 | 6989 |
| CD14 | 6998 |
| A1BG | 7060 |
| NHLRC3 | 7191 |
| C1R | 7201 |
| C5 | 7218 |
| FGB | 7226 |
| C8A | 7235 |
| PLA2G2A | 7254 |
| GCA | 7258 |
| TKFC | 7267 |
| UBE2L6 | 7272 |
| C4B | 7286 |
| PLD1 | 7290 |
| POLR3GL | 7315 |
| RNF125 | 7321 |
| SERPINA3 | 7328 |
| LEAP2 | 7329 |
| FGA | 7336 |
| C8B | 7343 |
| C4A | 7346 |
| CFB | 7350 |
| C3 | 7357 |
| C1S | 7360 |
| MUC5B | 7378 |
| TXNIP | 7384 |
| SERPING1 | 7387 |
Ribosomal scanning and start codon recognition
| 1014 | |
|---|---|
| set | Ribosomal scanning and start codon recognition |
| setSize | 58 |
| pANOVA | 1.02e-08 |
| s.dist | -0.435 |
| p.adjustANOVA | 2.93e-07 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| EIF4A1 | -6995 |
| EIF3A | -6965 |
| EIF5 | -6065 |
| EIF4G1 | -5901 |
| EIF4B | -5898 |
| EIF3I | -5279 |
| EIF2S1 | -5190 |
| RPS7 | -5138 |
| EIF3B | -5127 |
| EIF4H | -5055 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPS5 | -4778 |
| EIF3G | -4724 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| EIF3J | -4539 |
| EIF2S2 | -4458 |
| RPS12 | -4367 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| EIF4A1 | -6995 |
| EIF3A | -6965 |
| EIF5 | -6065 |
| EIF4G1 | -5901 |
| EIF4B | -5898 |
| EIF3I | -5279 |
| EIF2S1 | -5190 |
| RPS7 | -5138 |
| EIF3B | -5127 |
| EIF4H | -5055 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPS5 | -4778 |
| EIF3G | -4724 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| EIF3J | -4539 |
| EIF2S2 | -4458 |
| RPS12 | -4367 |
| EIF3M | -4358 |
| RPS9 | -4028 |
| RPS29 | -3844 |
| EIF3D | -3740 |
| EIF2S3 | -3669 |
| RPSA | -3520 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| RPS15A | -3019 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPS27A | -2773 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPS13 | -2581 |
| RPS23 | -2467 |
| EIF3L | -2407 |
| EIF3K | -2206 |
| RPS4Y1 | -2120 |
| RPS20 | -1754 |
| RPS8 | -1071 |
| RPS25 | -937 |
| EIF3F | -893 |
| EIF3C | -374 |
| EIF1AX | -274 |
| RPS3A | -179 |
| RPS27 | -152 |
| RPS26 | 419 |
| EIF3H | 899 |
| EIF4E | 2473 |
| EIF3E | 3244 |
| EIF4A2 | 5593 |
ER to Golgi Anterograde Transport
| 316 | |
|---|---|
| set | ER to Golgi Anterograde Transport |
| setSize | 122 |
| pANOVA | 1.24e-08 |
| s.dist | -0.299 |
| p.adjustANOVA | 3.49e-07 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SEC24D | -7134 |
| TMED2 | -7071 |
| MCFD2 | -7065 |
| MIA3 | -7049 |
| TMED7 | -6933 |
| SEC24A | -6839 |
| SEC13 | -6812 |
| ANK2 | -6778 |
| TMEM115 | -6764 |
| TRAPPC10 | -6585 |
| LMAN2 | -6558 |
| COPB2 | -6532 |
| CD55 | -6517 |
| PPP6R1 | -6511 |
| ARCN1 | -6505 |
| TMED9 | -6502 |
| SEC24C | -6236 |
| TBC1D20 | -6203 |
| TMED10 | -6116 |
| ARF1 | -6021 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SEC24D | -7134 |
| TMED2 | -7071 |
| MCFD2 | -7065 |
| MIA3 | -7049 |
| TMED7 | -6933 |
| SEC24A | -6839 |
| SEC13 | -6812 |
| ANK2 | -6778 |
| TMEM115 | -6764 |
| TRAPPC10 | -6585 |
| LMAN2 | -6558 |
| COPB2 | -6532 |
| CD55 | -6517 |
| PPP6R1 | -6511 |
| ARCN1 | -6505 |
| TMED9 | -6502 |
| SEC24C | -6236 |
| TBC1D20 | -6203 |
| TMED10 | -6116 |
| ARF1 | -6021 |
| SEC16A | -5971 |
| COPE | -5961 |
| COG3 | -5948 |
| NAPA | -5921 |
| KDELR2 | -5893 |
| ARF4 | -5812 |
| SEC31A | -5766 |
| CSNK1D | -5722 |
| SEC24B | -5475 |
| TFG | -5336 |
| GOLGA2 | -5310 |
| STX5 | -5300 |
| PPP6C | -5241 |
| ACTR1A | -5162 |
| COPG1 | -5135 |
| KDELR1 | -5094 |
| GBF1 | -4981 |
| SPTBN1 | -4901 |
| YKT6 | -4899 |
| CAPZA1 | -4855 |
| AREG | -4847 |
| NSF | -4839 |
| ARFGAP3 | -4817 |
| ANK1 | -4656 |
| TRAPPC2L | -4576 |
| TGFA | -4511 |
| CTSC | -4446 |
| COG2 | -4254 |
| COPB1 | -4098 |
| TMED3 | -4057 |
| TRAPPC3 | -4032 |
| COG5 | -3964 |
| COPA | -3958 |
| DCTN2 | -3957 |
| DYNC1LI2 | -3897 |
| NAPG | -3872 |
| DCTN5 | -3634 |
| DYNC1H1 | -3614 |
| USO1 | -3509 |
| GOLGB1 | -3498 |
| RAB1B | -3479 |
| LMAN1 | -3431 |
| LMAN2L | -3429 |
| RAB1A | -3307 |
| CD59 | -3245 |
| SAR1B | -2973 |
| DYNC1I2 | -2780 |
| SEC23A | -2717 |
| DYNC1LI1 | -2519 |
| ARF3 | -2430 |
| CNIH3 | -1958 |
| DCTN4 | -1937 |
| SEC22C | -1684 |
| DCTN1 | -1635 |
| ARFGAP1 | -1587 |
| CAPZA2 | -1549 |
| CAPZB | -1169 |
| PPP6R3 | -623 |
| NAPB | -419 |
| DCTN6 | -318 |
| CNIH1 | 212 |
| TRAPPC5 | 239 |
| ANK3 | 303 |
| SEC23IP | 390 |
| BET1 | 457 |
| SCFD1 | 485 |
| GOSR1 | 621 |
| F8 | 735 |
| COPZ1 | 782 |
| F5 | 831 |
| SEC22B | 859 |
| KDELR3 | 976 |
| GOSR2 | 1238 |
| ARFGAP2 | 1283 |
| PREB | 1446 |
| DCTN3 | 1457 |
| TRAPPC4 | 1781 |
| GORASP1 | 1903 |
| COG4 | 1972 |
| SPTAN1 | 2385 |
| DYNLL1 | 2509 |
| TRAPPC6B | 2584 |
| STX17 | 2586 |
| TRAPPC1 | 3089 |
| COG6 | 3264 |
| SEC22A | 3312 |
| BET1L | 3487 |
| TRAPPC2 | 3547 |
| SPTBN2 | 3883 |
| SERPINA1 | 4014 |
| ANKRD28 | 4146 |
| COG1 | 4586 |
| ARF5 | 4743 |
| COG7 | 4792 |
| TRAPPC9 | 5033 |
| COL7A1 | 5362 |
| ACTR10 | 5570 |
| DYNLL2 | 6044 |
| COPG2 | 6142 |
| SEC16B | 6744 |
| COG8 | 6745 |
| TRAPPC6A | 7244 |
Selenoamino acid metabolism
| 1056 | |
|---|---|
| set | Selenoamino acid metabolism |
| setSize | 104 |
| pANOVA | 1.3e-08 |
| s.dist | -0.323 |
| p.adjustANOVA | 3.57e-07 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| SCLY | -6834 |
| TXNRD1 | -6806 |
| SEPHS2 | -6447 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| CBS | -4541 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| RPL27A | -4297 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL36AL | -6981 |
| SCLY | -6834 |
| TXNRD1 | -6806 |
| SEPHS2 | -6447 |
| RPL19 | -5254 |
| RPS7 | -5138 |
| UBA52 | -5068 |
| RPL11 | -5032 |
| RPL10 | -5026 |
| RPS15 | -5010 |
| FAU | -4990 |
| RPL14 | -4978 |
| RPS5 | -4778 |
| RPS11 | -4702 |
| RPS19 | -4661 |
| RPS28 | -4652 |
| CBS | -4541 |
| RPLP1 | -4391 |
| RPS12 | -4367 |
| RPL27A | -4297 |
| RPLP0 | -4290 |
| RPL35A | -4159 |
| RPL30 | -4081 |
| RPS9 | -4028 |
| EEF1E1 | -4013 |
| RPL18 | -3961 |
| RPL26L1 | -3873 |
| RPS29 | -3844 |
| RPL6 | -3843 |
| RPL28 | -3546 |
| GSR | -3534 |
| RPSA | -3520 |
| RPL8 | -3467 |
| RPS4X | -3464 |
| RPS2 | -3462 |
| RPL29 | -3450 |
| RPL32 | -3448 |
| RPL36 | -3432 |
| RPL37 | -3413 |
| RPS17 | -3369 |
| RPS24 | -3352 |
| RPS14 | -3261 |
| RPS27L | -3180 |
| RPS10 | -3155 |
| RPS15A | -3019 |
| RPL7 | -2984 |
| RPL34 | -2974 |
| RPS21 | -2927 |
| RPS16 | -2898 |
| RPS3 | -2880 |
| RPL13A | -2872 |
| RPLP2 | -2863 |
| RPL35 | -2849 |
| RPS27A | -2773 |
| RPL23A | -2692 |
| RPL10A | -2689 |
| RPS6 | -2681 |
| RPS18 | -2648 |
| RPL41 | -2635 |
| RPS13 | -2581 |
| RPL4 | -2563 |
| RPS23 | -2467 |
| RPL37A | -2451 |
| RPL39 | -2270 |
| RPL18A | -2240 |
| RPL7A | -2233 |
| RPS4Y1 | -2120 |
| RPL27 | -2070 |
| AHCY | -1945 |
| RPL23 | -1913 |
| RPL24 | -1804 |
| RPL38 | -1791 |
| RPS20 | -1754 |
| RPL26 | -1747 |
| PSTK | -1545 |
| RPL15 | -1313 |
| RPL3 | -1165 |
| RPL17 | -1119 |
| RPS8 | -1071 |
| RPL12 | -983 |
| RPS25 | -937 |
| RPL13 | -706 |
| RPL5 | -495 |
| SECISBP2 | -410 |
| RPL22L1 | -214 |
| RPS3A | -179 |
| RPS27 | -152 |
| RPL9 | 261 |
| GNMT | 302 |
| RPL31 | 330 |
| RPS26 | 419 |
| AIMP2 | 1067 |
| RPL21 | 1385 |
| PAPSS2 | 1548 |
| AIMP1 | 1790 |
| RPL22 | 2142 |
| INMT | 2159 |
| RPL36A | 2875 |
| EEFSEC | 3653 |
| PAPSS1 | 3746 |
| HNMT | 4118 |
| MAT1A | 6114 |
| SEPSECS | 6852 |
| CTH | 7240 |
Here is the session info with all the versions of packages used.
sessionInfo()## R version 4.1.2 (2021-11-01)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 20.04.3 LTS
##
## Matrix products: default
## BLAS: /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.9.0
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.9.0
##
## locale:
## [1] LC_CTYPE=en_AU.UTF-8 LC_NUMERIC=C
## [3] LC_TIME=en_AU.UTF-8 LC_COLLATE=en_AU.UTF-8
## [5] LC_MONETARY=en_AU.UTF-8 LC_MESSAGES=en_AU.UTF-8
## [7] LC_PAPER=en_AU.UTF-8 LC_NAME=C
## [9] LC_ADDRESS=C LC_TELEPHONE=C
## [11] LC_MEASUREMENT=en_AU.UTF-8 LC_IDENTIFICATION=C
##
## attached base packages:
## [1] parallel stats4 stats graphics grDevices utils datasets
## [8] methods base
##
## other attached packages:
## [1] pkgload_1.2.4 GGally_2.1.2
## [3] ggplot2_3.3.5 reshape2_1.4.4
## [5] beeswarm_0.4.0 gplots_3.1.1
## [7] gtools_3.9.2 tibble_3.1.6
## [9] dplyr_1.0.7 echarts4r_0.4.3
## [11] eulerr_6.1.1 kableExtra_1.3.4
## [13] mitch_1.4.1 clusterProfiler_4.0.5
## [15] DESeq2_1.32.0 SummarizedExperiment_1.22.0
## [17] Biobase_2.52.0 MatrixGenerics_1.4.3
## [19] matrixStats_0.61.0 GenomicRanges_1.44.0
## [21] GenomeInfoDb_1.28.4 IRanges_2.26.0
## [23] S4Vectors_0.30.2 BiocGenerics_0.38.0
## [25] getDEE2_1.2.0
##
## loaded via a namespace (and not attached):
## [1] shadowtext_0.1.1 fastmatch_1.1-3 systemfonts_1.0.3
## [4] plyr_1.8.6 igraph_1.2.11 lazyeval_0.2.2
## [7] polylabelr_0.2.0 splines_4.1.2 BiocParallel_1.26.2
## [10] digest_0.6.29 yulab.utils_0.0.4 htmltools_0.5.2
## [13] GOSemSim_2.18.1 viridis_0.6.2 GO.db_3.13.0
## [16] fansi_1.0.0 magrittr_2.0.1 memoise_2.0.1
## [19] Biostrings_2.60.2 annotate_1.70.0 graphlayouts_0.8.0
## [22] svglite_2.0.0 enrichplot_1.12.3 colorspace_2.0-2
## [25] rvest_1.0.2 blob_1.2.2 ggrepel_0.9.1
## [28] xfun_0.29 tcltk_4.1.2 crayon_1.4.2
## [31] RCurl_1.98-1.5 jsonlite_1.7.2 scatterpie_0.1.7
## [34] genefilter_1.74.1 survival_3.2-13 ape_5.6-1
## [37] glue_1.6.0 polyclip_1.10-0 gtable_0.3.0
## [40] zlibbioc_1.38.0 XVector_0.32.0 webshot_0.5.2
## [43] htm2txt_2.1.1 DelayedArray_0.18.0 scales_1.1.1
## [46] DOSE_3.18.3 DBI_1.1.2 Rcpp_1.0.7
## [49] viridisLite_0.4.0 xtable_1.8-4 gridGraphics_0.5-1
## [52] tidytree_0.3.7 bit_4.0.4 htmlwidgets_1.5.4
## [55] httr_1.4.2 fgsea_1.18.0 RColorBrewer_1.1-2
## [58] ellipsis_0.3.2 pkgconfig_2.0.3 reshape_0.8.8
## [61] XML_3.99-0.8 farver_2.1.0 sass_0.4.0
## [64] locfit_1.5-9.4 utf8_1.2.2 labeling_0.4.2
## [67] ggplotify_0.1.0 tidyselect_1.1.1 rlang_0.4.12
## [70] later_1.3.0 AnnotationDbi_1.54.1 munsell_0.5.0
## [73] tools_4.1.2 cachem_1.0.6 downloader_0.4
## [76] generics_0.1.1 RSQLite_2.2.9 evaluate_0.14
## [79] stringr_1.4.0 fastmap_1.1.0 yaml_2.2.1
## [82] ggtree_3.0.4 knitr_1.37 bit64_4.0.5
## [85] tidygraph_1.2.0 caTools_1.18.2 purrr_0.3.4
## [88] KEGGREST_1.32.0 ggraph_2.0.5 nlme_3.1-153
## [91] mime_0.12 aplot_0.1.2 xml2_1.3.3
## [94] DO.db_2.9 rstudioapi_0.13 compiler_4.1.2
## [97] png_0.1-7 testthat_3.1.1 treeio_1.16.2
## [100] tweenr_1.0.2 geneplotter_1.70.0 bslib_0.3.1
## [103] stringi_1.7.6 highr_0.9 desc_1.4.0
## [106] lattice_0.20-45 Matrix_1.4-0 vctrs_0.3.8
## [109] pillar_1.6.4 lifecycle_1.0.1 jquerylib_0.1.4
## [112] data.table_1.14.2 cowplot_1.1.1 bitops_1.0-7
## [115] httpuv_1.6.5 patchwork_1.1.1 qvalue_2.24.0
## [118] R6_2.5.1 promises_1.2.0.1 KernSmooth_2.23-20
## [121] gridExtra_2.3 MASS_7.3-54 assertthat_0.2.1
## [124] rprojroot_2.0.2 withr_2.4.3 GenomeInfoDbData_1.2.6
## [127] grid_4.1.2 ggfun_0.0.4 tidyr_1.1.4
## [130] rmarkdown_2.11 ggforce_0.3.3 shiny_1.7.1END of report