Mitch Report
Antony Kaspi & Mark Ziemann
date generated: 2024-06-05
Background
Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch
Input profiles
Here is the first few lines of the input profile.
| x | |
|---|---|
| 0610009B22Rik | -0.3304181 |
| 0610009E02Rik | 0.7596333 |
| 0610009L18Rik | -1.2521412 |
| 0610010K14Rik | 0.4193627 |
| 0610012G03Rik | 1.4462155 |
| 0610030E20Rik | -0.2426628 |
Here are some metrics about the input data profile:
| Profile metrics | |
|---|---|
| num_genesets | 1604 |
| num_genes_in_profile | 17078 |
| duplicated_genes_present | 0 |
| num_profile_genes_in_sets | 8370 |
| num_profile_genes_not_in_sets | 8708 |
Here is a plot of the input profiles. Note the dynamic ranges.
Here is the contour plot of the profile including all detected genes.
Input genesets
Here are some metrics about the gene sets used:
GMT file of genesets:| Gene sets metrics | |
|---|---|
| num_genesets | 1604 |
| num_genesets_excluded | 425 |
| num_genesets_included | 1179 |
Differential pathway expression
Interactive enrichment scatterplot
Significance is calculated by -log10(p-value). All points shown are FDR<0.05.
Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.
Results table
Top N= 50 gene sets| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| POST CHAPERONIN TUBULIN FOLDING PATHWAY | 17 | 7.43e-06 | 0.628 | 5.67e-04 |
| TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE | 13 | 2.28e-04 | 0.590 | 5.96e-03 |
| FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | 19 | 1.23e-05 | 0.579 | 7.24e-04 |
| CGMP EFFECTS | 15 | 1.52e-04 | -0.565 | 4.61e-03 |
| REDUCTION OF CYTOSOLIC CA LEVELS | 11 | 1.33e-03 | -0.559 | 2.12e-02 |
| NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | 20 | 5.97e-05 | -0.518 | 2.20e-03 |
| SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III | 23 | 2.23e-05 | 0.511 | 1.09e-03 |
| P75NTR REGULATES AXONOGENESIS | 10 | 6.85e-03 | -0.494 | 6.59e-02 |
| APOPTOSIS INDUCED DNA FRAGMENTATION | 10 | 9.09e-03 | -0.476 | 7.99e-02 |
| WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 | 13 | 3.37e-03 | 0.470 | 4.01e-02 |
| CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION | 11 | 1.08e-02 | -0.444 | 9.12e-02 |
| GAP JUNCTION ASSEMBLY | 21 | 5.68e-04 | 0.434 | 1.12e-02 |
| IRE1ALPHA ACTIVATES CHAPERONES | 50 | 4.02e-07 | 0.414 | 7.89e-05 |
| GLYCOGEN STORAGE DISEASES | 12 | 1.42e-02 | 0.409 | 1.07e-01 |
| CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY | 13 | 1.11e-02 | 0.407 | 9.30e-02 |
| VOLTAGE GATED POTASSIUM CHANNELS | 39 | 1.42e-05 | -0.402 | 7.98e-04 |
| CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN | 36 | 4.14e-05 | 0.395 | 1.81e-03 |
| AGGREPHAGY | 35 | 5.79e-05 | 0.393 | 2.20e-03 |
| THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT | 66 | 5.42e-08 | 0.387 | 2.13e-05 |
| SODIUM CALCIUM EXCHANGERS | 10 | 3.53e-02 | -0.384 | 1.97e-01 |
| INTRAFLAGELLAR TRANSPORT | 51 | 2.06e-06 | 0.384 | 2.43e-04 |
| COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING | 26 | 7.26e-04 | 0.383 | 1.32e-02 |
| CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE | 11 | 2.81e-02 | -0.382 | 1.65e-01 |
| XENOBIOTICS | 10 | 3.77e-02 | -0.380 | 2.08e-01 |
| ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K | 11 | 2.96e-02 | -0.379 | 1.72e-01 |
| NEUROTOXICITY OF CLOSTRIDIUM TOXINS | 10 | 3.85e-02 | -0.378 | 2.08e-01 |
| SIGNALING BY FGFR4 IN DISEASE | 10 | 3.94e-02 | -0.376 | 2.11e-01 |
| DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | 23 | 1.96e-03 | -0.373 | 2.85e-02 |
| MET ACTIVATES RAP1 AND RAC1 | 10 | 4.21e-02 | -0.371 | 2.21e-01 |
| RHO GTPASES ACTIVATE WASPS AND WAVES | 36 | 1.23e-04 | -0.370 | 3.90e-03 |
| DEFECTIVE EXT2 CAUSES EXOSTOSES 2 | 14 | 2.04e-02 | 0.358 | 1.34e-01 |
| HDR THROUGH MMEJ ALT NHEJ | 10 | 5.02e-02 | -0.358 | 2.34e-01 |
| PI3K EVENTS IN ERBB2 SIGNALING | 15 | 1.73e-02 | -0.355 | 1.17e-01 |
| COHESIN LOADING ONTO CHROMATIN | 10 | 5.54e-02 | -0.350 | 2.50e-01 |
| CYTOSOLIC TRNA AMINOACYLATION | 24 | 3.01e-03 | 0.350 | 3.78e-02 |
| REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA | 13 | 3.02e-02 | 0.347 | 1.74e-01 |
| MATURATION OF NUCLEOPROTEIN | 10 | 5.85e-02 | -0.346 | 2.62e-01 |
| REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | 15 | 2.16e-02 | -0.343 | 1.38e-01 |
| ACTIVATION OF AMPK DOWNSTREAM OF NMDARS | 20 | 8.81e-03 | 0.338 | 7.86e-02 |
| CAMK IV MEDIATED PHOSPHORYLATION OF CREB | 10 | 6.44e-02 | -0.338 | 2.78e-01 |
| DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS | 18 | 1.41e-02 | 0.334 | 1.07e-01 |
| INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE | 22 | 6.93e-03 | 0.333 | 6.59e-02 |
| DISEASES OF CARBOHYDRATE METABOLISM | 28 | 2.47e-03 | 0.330 | 3.21e-02 |
| KERATAN SULFATE DEGRADATION | 12 | 5.17e-02 | 0.324 | 2.38e-01 |
| AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA | 53 | 4.71e-05 | 0.323 | 1.98e-03 |
| CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | 46 | 1.60e-04 | 0.322 | 4.61e-03 |
| KERATAN SULFATE BIOSYNTHESIS | 24 | 6.39e-03 | 0.322 | 6.38e-02 |
| SIGNALING BY FGFR3 FUSIONS IN CANCER | 10 | 7.92e-02 | -0.321 | 3.14e-01 |
| REGULATION OF RUNX3 EXPRESSION AND ACTIVITY | 53 | 5.75e-05 | 0.319 | 2.20e-03 |
| RA BIOSYNTHESIS PATHWAY | 12 | 5.54e-02 | 0.319 | 2.50e-01 |
Results (complete table)
Click HERE to show results for all gene sets
| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| POST CHAPERONIN TUBULIN FOLDING PATHWAY | 17 | 7.43e-06 | 0.628000 | 5.67e-04 |
| TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE | 13 | 2.28e-04 | 0.590000 | 5.96e-03 |
| FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | 19 | 1.23e-05 | 0.579000 | 7.24e-04 |
| CGMP EFFECTS | 15 | 1.52e-04 | -0.565000 | 4.61e-03 |
| REDUCTION OF CYTOSOLIC CA LEVELS | 11 | 1.33e-03 | -0.559000 | 2.12e-02 |
| NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | 20 | 5.97e-05 | -0.518000 | 2.20e-03 |
| SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III | 23 | 2.23e-05 | 0.511000 | 1.09e-03 |
| P75NTR REGULATES AXONOGENESIS | 10 | 6.85e-03 | -0.494000 | 6.59e-02 |
| APOPTOSIS INDUCED DNA FRAGMENTATION | 10 | 9.09e-03 | -0.476000 | 7.99e-02 |
| WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 | 13 | 3.37e-03 | 0.470000 | 4.01e-02 |
| CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION | 11 | 1.08e-02 | -0.444000 | 9.12e-02 |
| GAP JUNCTION ASSEMBLY | 21 | 5.68e-04 | 0.434000 | 1.12e-02 |
| IRE1ALPHA ACTIVATES CHAPERONES | 50 | 4.02e-07 | 0.414000 | 7.89e-05 |
| GLYCOGEN STORAGE DISEASES | 12 | 1.42e-02 | 0.409000 | 1.07e-01 |
| CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY | 13 | 1.11e-02 | 0.407000 | 9.30e-02 |
| VOLTAGE GATED POTASSIUM CHANNELS | 39 | 1.42e-05 | -0.402000 | 7.98e-04 |
| CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN | 36 | 4.14e-05 | 0.395000 | 1.81e-03 |
| AGGREPHAGY | 35 | 5.79e-05 | 0.393000 | 2.20e-03 |
| THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT | 66 | 5.42e-08 | 0.387000 | 2.13e-05 |
| SODIUM CALCIUM EXCHANGERS | 10 | 3.53e-02 | -0.384000 | 1.97e-01 |
| INTRAFLAGELLAR TRANSPORT | 51 | 2.06e-06 | 0.384000 | 2.43e-04 |
| COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING | 26 | 7.26e-04 | 0.383000 | 1.32e-02 |
| CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE | 11 | 2.81e-02 | -0.382000 | 1.65e-01 |
| XENOBIOTICS | 10 | 3.77e-02 | -0.380000 | 2.08e-01 |
| ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K | 11 | 2.96e-02 | -0.379000 | 1.72e-01 |
| NEUROTOXICITY OF CLOSTRIDIUM TOXINS | 10 | 3.85e-02 | -0.378000 | 2.08e-01 |
| SIGNALING BY FGFR4 IN DISEASE | 10 | 3.94e-02 | -0.376000 | 2.11e-01 |
| DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | 23 | 1.96e-03 | -0.373000 | 2.85e-02 |
| MET ACTIVATES RAP1 AND RAC1 | 10 | 4.21e-02 | -0.371000 | 2.21e-01 |
| RHO GTPASES ACTIVATE WASPS AND WAVES | 36 | 1.23e-04 | -0.370000 | 3.90e-03 |
| DEFECTIVE EXT2 CAUSES EXOSTOSES 2 | 14 | 2.04e-02 | 0.358000 | 1.34e-01 |
| HDR THROUGH MMEJ ALT NHEJ | 10 | 5.02e-02 | -0.358000 | 2.34e-01 |
| PI3K EVENTS IN ERBB2 SIGNALING | 15 | 1.73e-02 | -0.355000 | 1.17e-01 |
| COHESIN LOADING ONTO CHROMATIN | 10 | 5.54e-02 | -0.350000 | 2.50e-01 |
| CYTOSOLIC TRNA AMINOACYLATION | 24 | 3.01e-03 | 0.350000 | 3.78e-02 |
| REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA | 13 | 3.02e-02 | 0.347000 | 1.74e-01 |
| MATURATION OF NUCLEOPROTEIN | 10 | 5.85e-02 | -0.346000 | 2.62e-01 |
| REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | 15 | 2.16e-02 | -0.343000 | 1.38e-01 |
| ACTIVATION OF AMPK DOWNSTREAM OF NMDARS | 20 | 8.81e-03 | 0.338000 | 7.86e-02 |
| CAMK IV MEDIATED PHOSPHORYLATION OF CREB | 10 | 6.44e-02 | -0.338000 | 2.78e-01 |
| DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS | 18 | 1.41e-02 | 0.334000 | 1.07e-01 |
| INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE | 22 | 6.93e-03 | 0.333000 | 6.59e-02 |
| DISEASES OF CARBOHYDRATE METABOLISM | 28 | 2.47e-03 | 0.330000 | 3.21e-02 |
| KERATAN SULFATE DEGRADATION | 12 | 5.17e-02 | 0.324000 | 2.38e-01 |
| AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA | 53 | 4.71e-05 | 0.323000 | 1.98e-03 |
| CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | 46 | 1.60e-04 | 0.322000 | 4.61e-03 |
| KERATAN SULFATE BIOSYNTHESIS | 24 | 6.39e-03 | 0.322000 | 6.38e-02 |
| SIGNALING BY FGFR3 FUSIONS IN CANCER | 10 | 7.92e-02 | -0.321000 | 3.14e-01 |
| REGULATION OF RUNX3 EXPRESSION AND ACTIVITY | 53 | 5.75e-05 | 0.319000 | 2.20e-03 |
| RA BIOSYNTHESIS PATHWAY | 12 | 5.54e-02 | 0.319000 | 2.50e-01 |
| KERATAN SULFATE KERATIN METABOLISM | 30 | 2.56e-03 | 0.318000 | 3.28e-02 |
| NUCLEOTIDE LIKE PURINERGIC RECEPTORS | 13 | 4.82e-02 | -0.316000 | 2.29e-01 |
| METABOLISM OF STEROID HORMONES | 22 | 1.07e-02 | 0.314000 | 9.12e-02 |
| ASYMMETRIC LOCALIZATION OF PCP PROTEINS | 62 | 2.23e-05 | 0.311000 | 1.09e-03 |
| PHASE 0 RAPID DEPOLARISATION | 30 | 3.21e-03 | -0.311000 | 3.97e-02 |
| PROLONGED ERK ACTIVATION EVENTS | 14 | 4.42e-02 | -0.311000 | 2.22e-01 |
| MITOCHONDRIAL TRANSLATION | 93 | 2.34e-07 | 0.310000 | 6.89e-05 |
| STABILIZATION OF P53 | 54 | 8.06e-05 | 0.310000 | 2.64e-03 |
| ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING | 21 | 1.43e-02 | -0.309000 | 1.07e-01 |
| ASPARTATE AND ASPARAGINE METABOLISM | 10 | 9.16e-02 | -0.308000 | 3.49e-01 |
| HEDGEHOG LIGAND BIOGENESIS | 61 | 3.39e-05 | 0.307000 | 1.60e-03 |
| DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE | 20 | 1.84e-02 | 0.305000 | 1.23e-01 |
| MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS | 18 | 2.54e-02 | -0.304000 | 1.54e-01 |
| ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT | 23 | 1.16e-02 | 0.304000 | 9.56e-02 |
| TRNA AMINOACYLATION | 42 | 7.29e-04 | 0.301000 | 1.32e-02 |
| PREGNENOLONE BIOSYNTHESIS | 12 | 7.14e-02 | 0.301000 | 2.98e-01 |
| DCC MEDIATED ATTRACTIVE SIGNALING | 14 | 5.17e-02 | -0.300000 | 2.38e-01 |
| DEGRADATION OF AXIN | 53 | 1.61e-04 | 0.300000 | 4.61e-03 |
| HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR | 48 | 3.50e-04 | 0.298000 | 8.09e-03 |
| EUKARYOTIC TRANSLATION ELONGATION | 87 | 1.57e-06 | 0.298000 | 2.24e-04 |
| DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING | 59 | 7.97e-05 | 0.297000 | 2.64e-03 |
| ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | 15 | 4.71e-02 | 0.296000 | 2.28e-01 |
| GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | 19 | 2.58e-02 | -0.295000 | 1.54e-01 |
| ERBB2 ACTIVATES PTK6 SIGNALING | 11 | 9.14e-02 | -0.294000 | 3.49e-01 |
| HEME SIGNALING | 45 | 6.81e-04 | -0.293000 | 1.27e-02 |
| FCERI MEDIATED CA 2 MOBILIZATION | 26 | 9.89e-03 | -0.292000 | 8.63e-02 |
| UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION | 21 | 2.08e-02 | -0.291000 | 1.35e-01 |
| SHC1 EVENTS IN ERBB2 SIGNALING | 21 | 2.11e-02 | -0.291000 | 1.35e-01 |
| NEGATIVE REGULATION OF NOTCH4 SIGNALING | 54 | 2.46e-04 | 0.289000 | 6.16e-03 |
| HS GAG DEGRADATION | 21 | 2.22e-02 | 0.288000 | 1.41e-01 |
| RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA | 24 | 1.53e-02 | -0.286000 | 1.09e-01 |
| TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES | 11 | 1.00e-01 | -0.286000 | 3.69e-01 |
| CHOLESTEROL BIOSYNTHESIS | 24 | 1.53e-02 | 0.286000 | 1.09e-01 |
| GLUTATHIONE SYNTHESIS AND RECYCLING | 11 | 1.05e-01 | 0.283000 | 3.77e-01 |
| LONG TERM POTENTIATION | 23 | 1.98e-02 | -0.281000 | 1.32e-01 |
| PARASITE INFECTION | 55 | 3.23e-04 | -0.280000 | 7.70e-03 |
| GAP JUNCTION TRAFFICKING AND REGULATION | 33 | 5.48e-03 | 0.279000 | 5.69e-02 |
| JOSEPHIN DOMAIN DUBS | 11 | 1.10e-01 | 0.279000 | 3.85e-01 |
| ENDOSOMAL VACUOLAR PATHWAY | 11 | 1.10e-01 | -0.278000 | 3.85e-01 |
| ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 4.72e-02 | -0.278000 | 2.28e-01 |
| DEGRADATION OF DVL | 55 | 3.78e-04 | 0.277000 | 8.58e-03 |
| ERBB2 REGULATES CELL MOTILITY | 14 | 7.27e-02 | -0.277000 | 3.03e-01 |
| SIGNALING BY ERBB2 ECD MUTANTS | 16 | 5.52e-02 | -0.277000 | 2.50e-01 |
| DSCAM INTERACTIONS | 10 | 1.31e-01 | -0.276000 | 4.23e-01 |
| PROCESSIVE SYNTHESIS ON THE LAGGING STRAND | 15 | 6.45e-02 | 0.276000 | 2.78e-01 |
| SHC1 EVENTS IN EGFR SIGNALING | 11 | 1.14e-01 | -0.275000 | 3.94e-01 |
| OLFACTORY SIGNALING PATHWAY | 25 | 1.80e-02 | -0.273000 | 1.21e-01 |
| CONSTITUTIVE SIGNALING BY EGFRVIII | 15 | 6.72e-02 | -0.273000 | 2.86e-01 |
| ZINC TRANSPORTERS | 16 | 5.97e-02 | -0.272000 | 2.67e-01 |
| SIGNALING BY LEPTIN | 10 | 1.38e-01 | 0.271000 | 4.33e-01 |
| TRANSCRIPTIONAL REGULATION BY MECP2 | 59 | 3.27e-04 | -0.271000 | 7.70e-03 |
| VEGFR2 MEDIATED CELL PROLIFERATION | 19 | 4.13e-02 | -0.270000 | 2.17e-01 |
| PCP CE PATHWAY | 89 | 1.05e-05 | 0.270000 | 6.91e-04 |
| HEDGEHOG OFF STATE | 106 | 1.71e-06 | 0.269000 | 2.24e-04 |
| GLUCONEOGENESIS | 27 | 1.56e-02 | 0.269000 | 1.11e-01 |
| NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 10 | 1.41e-01 | -0.269000 | 4.37e-01 |
| ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION | 14 | 8.30e-02 | -0.268000 | 3.27e-01 |
| MITOCHONDRIAL TRNA AMINOACYLATION | 21 | 3.41e-02 | 0.267000 | 1.93e-01 |
| DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS | 59 | 3.98e-04 | 0.267000 | 8.86e-03 |
| SIGNALING BY ERBB2 IN CANCER | 25 | 2.10e-02 | -0.267000 | 1.35e-01 |
| DEGRADATION OF GLI1 BY THE PROTEASOME | 57 | 5.05e-04 | 0.266000 | 1.06e-02 |
| METABOLISM OF FAT SOLUBLE VITAMINS | 35 | 6.78e-03 | 0.264000 | 6.59e-02 |
| METAL ION SLC TRANSPORTERS | 25 | 2.25e-02 | -0.264000 | 1.41e-01 |
| REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO | 10 | 1.52e-01 | -0.262000 | 4.47e-01 |
| SIGNALING BY BMP | 25 | 2.38e-02 | -0.261000 | 1.46e-01 |
| APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | 70 | 1.64e-04 | 0.261000 | 4.61e-03 |
| CA DEPENDENT EVENTS | 36 | 6.84e-03 | -0.260000 | 6.59e-02 |
| MISCELLANEOUS TRANSPORT AND BINDING EVENTS | 20 | 4.54e-02 | -0.258000 | 2.25e-01 |
| TRANSLATION | 286 | 6.48e-14 | 0.258000 | 7.64e-11 |
| CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT | 20 | 4.59e-02 | -0.258000 | 2.26e-01 |
| SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | 16 | 7.47e-02 | -0.257000 | 3.08e-01 |
| DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM | 40 | 4.90e-03 | 0.257000 | 5.34e-02 |
| AMINE LIGAND BINDING RECEPTORS | 29 | 1.68e-02 | -0.257000 | 1.16e-01 |
| A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | 26 | 2.38e-02 | 0.256000 | 1.46e-01 |
| MITOCHONDRIAL PROTEIN IMPORT | 63 | 4.47e-04 | 0.256000 | 9.69e-03 |
| METABOLISM OF POLYAMINES | 57 | 8.64e-04 | 0.255000 | 1.52e-02 |
| ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING | 10 | 1.62e-01 | -0.255000 | 4.63e-01 |
| TIE2 SIGNALING | 17 | 6.91e-02 | -0.255000 | 2.91e-01 |
| NF KB IS ACTIVATED AND SIGNALS SURVIVAL | 13 | 1.12e-01 | 0.255000 | 3.90e-01 |
| HSF1 ACTIVATION | 25 | 2.86e-02 | 0.253000 | 1.67e-01 |
| REGULATION OF HMOX1 EXPRESSION AND ACTIVITY | 63 | 5.24e-04 | 0.253000 | 1.08e-02 |
| ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS | 18 | 6.38e-02 | 0.252000 | 2.77e-01 |
| G PROTEIN MEDIATED EVENTS | 52 | 1.65e-03 | -0.252000 | 2.47e-02 |
| REGULATION OF MECP2 EXPRESSION AND ACTIVITY | 30 | 1.70e-02 | -0.252000 | 1.16e-01 |
| SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | 106 | 7.70e-06 | 0.252000 | 5.67e-04 |
| BLOOD GROUP SYSTEMS BIOSYNTHESIS | 13 | 1.17e-01 | -0.251000 | 3.98e-01 |
| PEXOPHAGY | 11 | 1.51e-01 | 0.250000 | 4.45e-01 |
| SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS | 12 | 1.34e-01 | -0.250000 | 4.27e-01 |
| UNFOLDED PROTEIN RESPONSE UPR | 86 | 7.18e-05 | 0.248000 | 2.49e-03 |
| DAG AND IP3 SIGNALING | 40 | 6.91e-03 | -0.247000 | 6.59e-02 |
| INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION | 13 | 1.23e-01 | -0.247000 | 4.07e-01 |
| SCF SKP2 MEDIATED DEGRADATION OF P27 P21 | 59 | 1.11e-03 | 0.246000 | 1.81e-02 |
| HSF1 DEPENDENT TRANSACTIVATION | 33 | 1.48e-02 | 0.245000 | 1.09e-01 |
| PYRIMIDINE SALVAGE | 10 | 1.81e-01 | 0.244000 | 4.85e-01 |
| ATTENUATION PHASE | 23 | 4.40e-02 | 0.243000 | 2.22e-01 |
| POTASSIUM CHANNELS | 91 | 7.04e-05 | -0.241000 | 2.49e-03 |
| RHO GTPASES ACTIVATE IQGAPS | 24 | 4.11e-02 | 0.241000 | 2.17e-01 |
| RORA ACTIVATES GENE EXPRESSION | 18 | 7.68e-02 | -0.241000 | 3.10e-01 |
| TERMINATION OF O GLYCAN BIOSYNTHESIS | 10 | 1.87e-01 | 0.241000 | 4.90e-01 |
| SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL | 13 | 1.34e-01 | -0.240000 | 4.27e-01 |
| TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY | 12 | 1.51e-01 | 0.239000 | 4.45e-01 |
| SELENOAMINO ACID METABOLISM | 109 | 1.74e-05 | 0.238000 | 9.34e-04 |
| SIGNALING BY HIPPO | 20 | 6.53e-02 | -0.238000 | 2.80e-01 |
| G1 S DNA DAMAGE CHECKPOINTS | 65 | 9.57e-04 | 0.237000 | 1.61e-02 |
| CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | 12 | 1.55e-01 | -0.237000 | 4.51e-01 |
| APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS | 81 | 2.42e-04 | 0.236000 | 6.16e-03 |
| CROSSLINKING OF COLLAGEN FIBRILS | 16 | 1.05e-01 | 0.234000 | 3.77e-01 |
| VLDLR INTERNALISATION AND DEGRADATION | 12 | 1.61e-01 | 0.234000 | 4.59e-01 |
| INTERLEUKIN 10 SIGNALING | 19 | 7.78e-02 | -0.234000 | 3.11e-01 |
| GAB1 SIGNALOSOME | 14 | 1.30e-01 | -0.234000 | 4.23e-01 |
| ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | 38 | 1.29e-02 | 0.233000 | 1.01e-01 |
| REGULATION OF PTEN STABILITY AND ACTIVITY | 66 | 1.13e-03 | 0.232000 | 1.83e-02 |
| COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 44 | 7.85e-03 | 0.232000 | 7.12e-02 |
| GRB2 EVENTS IN ERBB2 SIGNALING | 15 | 1.23e-01 | -0.230000 | 4.05e-01 |
| INTERACTION BETWEEN L1 AND ANKYRINS | 28 | 3.52e-02 | -0.230000 | 1.97e-01 |
| SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | 20 | 7.51e-02 | -0.230000 | 3.08e-01 |
| RMTS METHYLATE HISTONE ARGININES | 45 | 7.65e-03 | 0.230000 | 7.02e-02 |
| ACTIVATION OF RAC1 | 13 | 1.52e-01 | -0.229000 | 4.47e-01 |
| DEADENYLATION OF MRNA | 25 | 4.78e-02 | -0.229000 | 2.29e-01 |
| NS1 MEDIATED EFFECTS ON HOST PATHWAYS | 37 | 1.67e-02 | -0.227000 | 1.16e-01 |
| DARPP 32 EVENTS | 23 | 6.33e-02 | -0.224000 | 2.77e-01 |
| RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES | 20 | 8.34e-02 | -0.224000 | 3.27e-01 |
| REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION | 10 | 2.21e-01 | -0.224000 | 5.31e-01 |
| COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES | 62 | 2.36e-03 | 0.223000 | 3.15e-02 |
| CARDIAC CONDUCTION | 109 | 5.98e-05 | -0.223000 | 2.20e-03 |
| SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS | 73 | 1.02e-03 | -0.222000 | 1.69e-02 |
| CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING | 28 | 4.23e-02 | -0.222000 | 2.21e-01 |
| MITOTIC TELOPHASE CYTOKINESIS | 13 | 1.67e-01 | -0.222000 | 4.66e-01 |
| TNFR2 NON CANONICAL NF KB PATHWAY | 79 | 6.66e-04 | 0.222000 | 1.27e-02 |
| RNA POLYMERASE III CHAIN ELONGATION | 18 | 1.05e-01 | 0.221000 | 3.77e-01 |
| HDMS DEMETHYLATE HISTONES | 28 | 4.36e-02 | -0.220000 | 2.22e-01 |
| FCERI MEDIATED MAPK ACTIVATION | 28 | 4.37e-02 | -0.220000 | 2.22e-01 |
| NEUROTRANSMITTER RELEASE CYCLE | 49 | 7.68e-03 | -0.220000 | 7.02e-02 |
| SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | 11 | 2.07e-01 | -0.220000 | 5.13e-01 |
| RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY | 95 | 2.16e-04 | 0.220000 | 5.78e-03 |
| INTERFERON GAMMA SIGNALING | 77 | 8.62e-04 | -0.220000 | 1.52e-02 |
| INSULIN PROCESSING | 24 | 6.31e-02 | -0.219000 | 2.77e-01 |
| TRAF6 MEDIATED IRF7 ACTIVATION | 15 | 1.43e-01 | -0.219000 | 4.37e-01 |
| RECYCLING PATHWAY OF L1 | 40 | 1.67e-02 | 0.219000 | 1.16e-01 |
| MISMATCH REPAIR | 14 | 1.58e-01 | 0.218000 | 4.54e-01 |
| NUCLEOTIDE SALVAGE | 21 | 8.40e-02 | 0.218000 | 3.27e-01 |
| REGULATION OF TP53 ACTIVITY THROUGH METHYLATION | 18 | 1.10e-01 | 0.218000 | 3.85e-01 |
| CA2 PATHWAY | 58 | 4.19e-03 | -0.217000 | 4.71e-02 |
| LATE ENDOSOMAL MICROAUTOPHAGY | 32 | 3.35e-02 | 0.217000 | 1.92e-01 |
| SUMOYLATION OF RNA BINDING PROTEINS | 45 | 1.21e-02 | -0.216000 | 9.86e-02 |
| SELECTIVE AUTOPHAGY | 72 | 1.59e-03 | 0.215000 | 2.40e-02 |
| RHOJ GTPASE CYCLE | 54 | 6.23e-03 | -0.215000 | 6.28e-02 |
| SIGNALING BY HEDGEHOG | 141 | 1.09e-05 | 0.215000 | 6.91e-04 |
| WNT5A DEPENDENT INTERNALIZATION OF FZD4 | 15 | 1.50e-01 | 0.215000 | 4.45e-01 |
| INTERLEUKIN 6 SIGNALING | 10 | 2.41e-01 | 0.214000 | 5.51e-01 |
| SIGNALING BY PDGFR IN DISEASE | 20 | 9.74e-02 | -0.214000 | 3.62e-01 |
| RHOQ GTPASE CYCLE | 58 | 4.82e-03 | -0.214000 | 5.32e-02 |
| REGULATION OF EXPRESSION OF SLITS AND ROBOS | 160 | 3.17e-06 | 0.214000 | 3.11e-04 |
| TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | 43 | 1.70e-02 | -0.210000 | 1.16e-01 |
| TIGHT JUNCTION INTERACTIONS | 17 | 1.33e-01 | -0.210000 | 4.27e-01 |
| ADHERENS JUNCTIONS INTERACTIONS | 30 | 4.65e-02 | -0.210000 | 2.26e-01 |
| ACTIVATION OF SMO | 16 | 1.46e-01 | 0.210000 | 4.42e-01 |
| COPI MEDIATED ANTEROGRADE TRANSPORT | 91 | 5.51e-04 | 0.210000 | 1.10e-02 |
| RESPONSE OF MTB TO PHAGOCYTOSIS | 21 | 9.73e-02 | 0.209000 | 3.62e-01 |
| SIGNALING BY FLT3 FUSION PROTEINS | 19 | 1.15e-01 | -0.209000 | 3.95e-01 |
| RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE | 24 | 7.65e-02 | 0.209000 | 3.10e-01 |
| FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES | 16 | 1.49e-01 | -0.209000 | 4.45e-01 |
| REGULATION OF RAS BY GAPS | 66 | 3.44e-03 | 0.208000 | 4.05e-02 |
| CELLULAR RESPONSE TO HYPOXIA | 72 | 2.36e-03 | 0.207000 | 3.15e-02 |
| ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | 73 | 2.44e-03 | -0.205000 | 3.20e-02 |
| CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | 12 | 2.18e-01 | 0.205000 | 5.30e-01 |
| INTERFERON SIGNALING | 165 | 5.65e-06 | -0.205000 | 4.75e-04 |
| CELL CELL JUNCTION ORGANIZATION | 49 | 1.31e-02 | -0.205000 | 1.02e-01 |
| HIV ELONGATION ARREST AND RECOVERY | 32 | 4.50e-02 | 0.205000 | 2.24e-01 |
| FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES | 24 | 8.31e-02 | -0.204000 | 3.27e-01 |
| ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS | 10 | 2.64e-01 | -0.204000 | 5.74e-01 |
| PHASE 4 RESTING MEMBRANE POTENTIAL | 14 | 1.87e-01 | -0.204000 | 4.90e-01 |
| ABC TRANSPORTER DISORDERS | 70 | 3.24e-03 | 0.204000 | 3.97e-02 |
| PLASMA LIPOPROTEIN CLEARANCE | 28 | 6.24e-02 | 0.204000 | 2.76e-01 |
| TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX | 12 | 2.24e-01 | 0.203000 | 5.35e-01 |
| SIGNALING BY FGFR1 IN DISEASE | 33 | 4.41e-02 | -0.203000 | 2.22e-01 |
| MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES | 31 | 5.16e-02 | -0.202000 | 2.38e-01 |
| EUKARYOTIC TRANSLATION INITIATION | 114 | 1.97e-04 | 0.202000 | 5.40e-03 |
| RRNA PROCESSING | 194 | 1.26e-06 | 0.202000 | 2.12e-04 |
| MRNA SPLICING MINOR PATHWAY | 52 | 1.21e-02 | 0.201000 | 9.86e-02 |
| TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY | 29 | 6.27e-02 | 0.200000 | 2.77e-01 |
| ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS | 26 | 7.83e-02 | -0.199000 | 3.12e-01 |
| SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP | 65 | 5.47e-03 | 0.199000 | 5.69e-02 |
| LYSOSPHINGOLIPID AND LPA RECEPTORS | 13 | 2.14e-01 | -0.199000 | 5.24e-01 |
| REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM | 11 | 2.54e-01 | 0.199000 | 5.62e-01 |
| RIP MEDIATED NFKB ACTIVATION VIA ZBP1 | 15 | 1.84e-01 | 0.198000 | 4.89e-01 |
| SUMOYLATION OF SUMOYLATION PROTEINS | 33 | 4.95e-02 | -0.198000 | 2.32e-01 |
| RAP1 SIGNALLING | 15 | 1.86e-01 | -0.197000 | 4.89e-01 |
| ACETYLCHOLINE REGULATES INSULIN SECRETION | 10 | 2.82e-01 | -0.197000 | 5.92e-01 |
| BUDDING AND MATURATION OF HIV VIRION | 27 | 7.73e-02 | 0.196000 | 3.10e-01 |
| HEDGEHOG ON STATE | 82 | 2.17e-03 | 0.196000 | 3.04e-02 |
| KINESINS | 47 | 2.04e-02 | 0.196000 | 1.34e-01 |
| HS GAG BIOSYNTHESIS | 29 | 6.90e-02 | 0.195000 | 2.91e-01 |
| REGULATION OF TNFR1 SIGNALING | 34 | 4.93e-02 | 0.195000 | 2.32e-01 |
| SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | 20 | 1.32e-01 | 0.195000 | 4.26e-01 |
| NONSENSE MEDIATED DECAY NMD | 109 | 4.52e-04 | 0.195000 | 9.69e-03 |
| NUCLEAR PORE COMPLEX NPC DISASSEMBLY | 32 | 5.71e-02 | -0.194000 | 2.57e-01 |
| DEGRADATION OF CYSTEINE AND HOMOCYSTEINE | 12 | 2.44e-01 | 0.194000 | 5.55e-01 |
| COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 86 | 1.98e-03 | 0.193000 | 2.85e-02 |
| RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER | 28 | 7.73e-02 | 0.193000 | 3.10e-01 |
| EARLY PHASE OF HIV LIFE CYCLE | 13 | 2.30e-01 | -0.192000 | 5.41e-01 |
| SULFUR AMINO ACID METABOLISM | 22 | 1.18e-01 | 0.192000 | 3.98e-01 |
| DISEASES OF METABOLISM | 199 | 3.16e-06 | 0.192000 | 3.11e-04 |
| GABA RECEPTOR ACTIVATION | 54 | 1.49e-02 | -0.192000 | 1.09e-01 |
| ION HOMEOSTASIS | 49 | 2.05e-02 | -0.191000 | 1.34e-01 |
| BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION | 26 | 9.14e-02 | -0.191000 | 3.49e-01 |
| ACTIVATION OF THE PRE REPLICATIVE COMPLEX | 29 | 7.47e-02 | -0.191000 | 3.08e-01 |
| TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS | 54 | 1.53e-02 | -0.191000 | 1.09e-01 |
| SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS | 58 | 1.24e-02 | -0.190000 | 9.98e-02 |
| RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR | 20 | 1.42e-01 | -0.190000 | 4.37e-01 |
| RAB GERANYLGERANYLATION | 57 | 1.34e-02 | -0.189000 | 1.02e-01 |
| BETA CATENIN PHOSPHORYLATION CASCADE | 16 | 1.91e-01 | -0.189000 | 4.94e-01 |
| COMPLEX I BIOGENESIS | 56 | 1.45e-02 | 0.189000 | 1.08e-01 |
| INTERFERON ALPHA BETA SIGNALING | 56 | 1.49e-02 | -0.188000 | 1.09e-01 |
| CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY | 84 | 2.88e-03 | 0.188000 | 3.66e-02 |
| RUNX3 REGULATES NOTCH SIGNALING | 13 | 2.41e-01 | -0.188000 | 5.51e-01 |
| E2F MEDIATED REGULATION OF DNA REPLICATION | 19 | 1.57e-01 | -0.188000 | 4.54e-01 |
| COLLAGEN FORMATION | 79 | 3.98e-03 | 0.187000 | 4.61e-02 |
| MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS | 13 | 2.42e-01 | 0.187000 | 5.51e-01 |
| NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS | 11 | 2.82e-01 | 0.187000 | 5.92e-01 |
| BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS | 11 | 2.83e-01 | 0.187000 | 5.92e-01 |
| GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | 30 | 7.64e-02 | 0.187000 | 3.10e-01 |
| HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE | 40 | 4.09e-02 | -0.187000 | 2.17e-01 |
| MYOGENESIS | 25 | 1.06e-01 | -0.187000 | 3.77e-01 |
| SIGNALING BY ERYTHROPOIETIN | 24 | 1.13e-01 | -0.187000 | 3.92e-01 |
| INTERLEUKIN 20 FAMILY SIGNALING | 14 | 2.27e-01 | 0.186000 | 5.38e-01 |
| UCH PROTEINASES | 90 | 2.28e-03 | 0.186000 | 3.13e-02 |
| FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS | 82 | 3.61e-03 | -0.186000 | 4.21e-02 |
| THE PHOTOTRANSDUCTION CASCADE | 21 | 1.40e-01 | -0.186000 | 4.36e-01 |
| POLYMERASE SWITCHING | 14 | 2.30e-01 | 0.185000 | 5.41e-01 |
| LDL CLEARANCE | 16 | 2.02e-01 | 0.184000 | 5.08e-01 |
| ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES | 10 | 3.18e-01 | 0.183000 | 6.20e-01 |
| SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS | 15 | 2.21e-01 | -0.182000 | 5.32e-01 |
| ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | 33 | 6.99e-02 | -0.182000 | 2.93e-01 |
| SIGNALING BY VEGF | 103 | 1.45e-03 | -0.182000 | 2.25e-02 |
| THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION | 15 | 2.23e-01 | 0.182000 | 5.35e-01 |
| RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS | 84 | 4.09e-03 | 0.181000 | 4.64e-02 |
| ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | 30 | 8.69e-02 | 0.181000 | 3.37e-01 |
| CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | 19 | 1.74e-01 | 0.180000 | 4.75e-01 |
| CYTOCHROME C MEDIATED APOPTOTIC RESPONSE | 12 | 2.82e-01 | -0.179000 | 5.92e-01 |
| REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS | 15 | 2.29e-01 | -0.179000 | 5.41e-01 |
| PROTEIN FOLDING | 90 | 3.32e-03 | 0.179000 | 4.01e-02 |
| SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | 52 | 2.58e-02 | -0.179000 | 1.54e-01 |
| METABOLISM OF AMINO ACIDS AND DERIVATIVES | 317 | 4.70e-08 | 0.179000 | 2.13e-05 |
| MUCOPOLYSACCHARIDOSES | 11 | 3.05e-01 | 0.179000 | 6.05e-01 |
| REGULATION OF GENE EXPRESSION IN BETA CELLS | 10 | 3.29e-01 | -0.178000 | 6.26e-01 |
| REGULATION OF IFNA SIGNALING | 12 | 2.86e-01 | 0.178000 | 5.94e-01 |
| HEPARAN SULFATE HEPARIN HS GAG METABOLISM | 52 | 2.67e-02 | 0.178000 | 1.57e-01 |
| CHEMOKINE RECEPTORS BIND CHEMOKINES | 16 | 2.19e-01 | -0.178000 | 5.30e-01 |
| NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | 12 | 2.88e-01 | -0.177000 | 5.95e-01 |
| CHAPERONE MEDIATED AUTOPHAGY | 21 | 1.60e-01 | 0.177000 | 4.59e-01 |
| FCERI MEDIATED NF KB ACTIVATION | 77 | 7.26e-03 | 0.177000 | 6.79e-02 |
| PIWI INTERACTING RNA PIRNA BIOGENESIS | 19 | 1.82e-01 | 0.177000 | 4.86e-01 |
| OPIOID SIGNALLING | 87 | 4.52e-03 | -0.176000 | 5.02e-02 |
| TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 | 12 | 2.91e-01 | 0.176000 | 5.95e-01 |
| FREE FATTY ACIDS REGULATE INSULIN SECRETION | 10 | 3.35e-01 | -0.176000 | 6.28e-01 |
| SYNTHESIS OF PE | 13 | 2.72e-01 | 0.176000 | 5.86e-01 |
| GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 12 | 2.92e-01 | -0.176000 | 5.95e-01 |
| THE NLRP3 INFLAMMASOME | 15 | 2.42e-01 | 0.175000 | 5.51e-01 |
| EXTRA NUCLEAR ESTROGEN SIGNALING | 68 | 1.29e-02 | -0.175000 | 1.01e-01 |
| EFFECTS OF PIP2 HYDROLYSIS | 27 | 1.17e-01 | -0.174000 | 3.98e-01 |
| ORGANIC CATION ANION ZWITTERION TRANSPORT | 12 | 2.96e-01 | 0.174000 | 5.98e-01 |
| METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES | 21 | 1.68e-01 | 0.174000 | 4.67e-01 |
| ASSEMBLY OF THE HIV VIRION | 16 | 2.31e-01 | 0.173000 | 5.41e-01 |
| SIGNALING BY NTRK2 TRKB | 24 | 1.43e-01 | -0.173000 | 4.37e-01 |
| TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST | 15 | 2.47e-01 | 0.173000 | 5.57e-01 |
| ENOS ACTIVATION | 11 | 3.23e-01 | -0.172000 | 6.20e-01 |
| MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | 15 | 2.49e-01 | 0.172000 | 5.57e-01 |
| OTHER SEMAPHORIN INTERACTIONS | 19 | 1.95e-01 | -0.172000 | 4.98e-01 |
| SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS | 18 | 2.08e-01 | -0.171000 | 5.15e-01 |
| EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS | 31 | 9.97e-02 | -0.171000 | 3.68e-01 |
| AUTOPHAGY | 139 | 5.47e-04 | 0.170000 | 1.10e-02 |
| REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | 84 | 7.15e-03 | 0.170000 | 6.74e-02 |
| IRAK4 DEFICIENCY TLR2 4 | 13 | 2.91e-01 | -0.169000 | 5.95e-01 |
| RHO GTPASES ACTIVATE NADPH OXIDASES | 21 | 1.80e-01 | -0.169000 | 4.85e-01 |
| APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B | 21 | 1.81e-01 | 0.169000 | 4.85e-01 |
| BIOTIN TRANSPORT AND METABOLISM | 11 | 3.33e-01 | 0.169000 | 6.26e-01 |
| DAP12 INTERACTIONS | 31 | 1.05e-01 | -0.168000 | 3.77e-01 |
| APC CDC20 MEDIATED DEGRADATION OF NEK2A | 24 | 1.54e-01 | 0.168000 | 4.49e-01 |
| GLUTAMATE AND GLUTAMINE METABOLISM | 13 | 2.94e-01 | 0.168000 | 5.96e-01 |
| CARNITINE METABOLISM | 14 | 2.79e-01 | 0.167000 | 5.91e-01 |
| POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE | 25 | 1.49e-01 | 0.167000 | 4.45e-01 |
| SHC1 EVENTS IN ERBB4 SIGNALING | 13 | 2.99e-01 | -0.167000 | 6.01e-01 |
| NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION | 21 | 1.89e-01 | -0.166000 | 4.90e-01 |
| RAC2 GTPASE CYCLE | 87 | 7.64e-03 | -0.166000 | 7.02e-02 |
| INTERLEUKIN 1 SIGNALING | 96 | 5.11e-03 | 0.165000 | 5.48e-02 |
| CD209 DC SIGN SIGNALING | 18 | 2.25e-01 | -0.165000 | 5.36e-01 |
| TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN | 20 | 2.02e-01 | -0.165000 | 5.08e-01 |
| FORMATION OF THE CORNIFIED ENVELOPE | 30 | 1.18e-01 | 0.165000 | 3.98e-01 |
| KERATINIZATION | 30 | 1.18e-01 | 0.165000 | 3.98e-01 |
| GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | 23 | 1.72e-01 | -0.165000 | 4.71e-01 |
| PKA MEDIATED PHOSPHORYLATION OF CREB | 19 | 2.15e-01 | -0.164000 | 5.25e-01 |
| CELLULAR RESPONSE TO STARVATION | 146 | 6.27e-04 | 0.164000 | 1.21e-02 |
| FGFR1 MUTANT RECEPTOR ACTIVATION | 26 | 1.49e-01 | -0.163000 | 4.45e-01 |
| BBSOME MEDIATED CARGO TARGETING TO CILIUM | 23 | 1.75e-01 | 0.163000 | 4.78e-01 |
| PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES | 13 | 3.09e-01 | -0.163000 | 6.09e-01 |
| PYRUVATE METABOLISM | 27 | 1.43e-01 | -0.163000 | 4.37e-01 |
| DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX | 82 | 1.08e-02 | 0.163000 | 9.12e-02 |
| ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS | 35 | 9.57e-02 | 0.163000 | 3.60e-01 |
| PI METABOLISM | 79 | 1.24e-02 | -0.163000 | 9.98e-02 |
| FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF | 14 | 2.92e-01 | -0.163000 | 5.95e-01 |
| CYTOSOLIC SULFONATION OF SMALL MOLECULES | 15 | 2.77e-01 | 0.162000 | 5.89e-01 |
| CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND | 10 | 3.74e-01 | -0.162000 | 6.72e-01 |
| PECAM1 INTERACTIONS | 12 | 3.31e-01 | -0.162000 | 6.26e-01 |
| DAP12 SIGNALING | 24 | 1.69e-01 | -0.162000 | 4.68e-01 |
| INFECTION WITH MYCOBACTERIUM TUBERCULOSIS | 24 | 1.69e-01 | 0.162000 | 4.68e-01 |
| INHIBITION OF DNA RECOMBINATION AT TELOMERE | 37 | 8.95e-02 | 0.161000 | 3.46e-01 |
| SUMOYLATION OF UBIQUITINYLATION PROTEINS | 37 | 9.12e-02 | -0.160000 | 3.49e-01 |
| DNA METHYLATION | 22 | 1.93e-01 | 0.160000 | 4.96e-01 |
| FGFR2 ALTERNATIVE SPLICING | 25 | 1.67e-01 | 0.160000 | 4.66e-01 |
| FORMATION OF THE EARLY ELONGATION COMPLEX | 33 | 1.12e-01 | 0.160000 | 3.90e-01 |
| ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | 59 | 3.39e-02 | 0.160000 | 1.93e-01 |
| DISEASES OF GLYCOSYLATION | 125 | 2.10e-03 | 0.159000 | 2.98e-02 |
| NEUREXINS AND NEUROLIGINS | 54 | 4.28e-02 | -0.159000 | 2.22e-01 |
| GLYCOSAMINOGLYCAN METABOLISM | 114 | 3.36e-03 | 0.159000 | 4.01e-02 |
| NUCLEAR IMPORT OF REV PROTEIN | 32 | 1.20e-01 | -0.159000 | 4.01e-01 |
| LAGGING STRAND SYNTHESIS | 20 | 2.19e-01 | 0.159000 | 5.30e-01 |
| CILIUM ASSEMBLY | 191 | 1.61e-04 | 0.159000 | 4.61e-03 |
| DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | 13 | 3.23e-01 | 0.158000 | 6.20e-01 |
| SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL | 10 | 3.87e-01 | 0.158000 | 6.77e-01 |
| BASE EXCISION REPAIR AP SITE FORMATION | 31 | 1.28e-01 | 0.158000 | 4.20e-01 |
| RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | 125 | 2.38e-03 | 0.157000 | 3.15e-02 |
| SEROTONIN NEUROTRANSMITTER RELEASE CYCLE | 18 | 2.47e-01 | -0.157000 | 5.57e-01 |
| FANCONI ANEMIA PATHWAY | 36 | 1.02e-01 | 0.157000 | 3.75e-01 |
| RESPIRATORY ELECTRON TRANSPORT | 102 | 6.09e-03 | 0.157000 | 6.19e-02 |
| CITRIC ACID CYCLE TCA CYCLE | 22 | 2.03e-01 | 0.157000 | 5.08e-01 |
| EPHA MEDIATED GROWTH CONE COLLAPSE | 29 | 1.45e-01 | -0.157000 | 4.39e-01 |
| FOXO MEDIATED TRANSCRIPTION | 58 | 3.93e-02 | -0.157000 | 2.11e-01 |
| RESOLUTION OF D LOOP STRUCTURES | 30 | 1.39e-01 | -0.156000 | 4.35e-01 |
| P75NTR SIGNALS VIA NF KB | 16 | 2.81e-01 | 0.156000 | 5.92e-01 |
| SEMA4D IN SEMAPHORIN SIGNALING | 24 | 1.88e-01 | 0.155000 | 4.90e-01 |
| KILLING MECHANISMS | 11 | 3.73e-01 | 0.155000 | 6.70e-01 |
| SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | 13 | 3.33e-01 | 0.155000 | 6.26e-01 |
| METABOLISM OF FOLATE AND PTERINES | 15 | 2.99e-01 | 0.155000 | 6.01e-01 |
| N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | 25 | 1.81e-01 | 0.155000 | 4.85e-01 |
| RAC3 GTPASE CYCLE | 90 | 1.12e-02 | -0.155000 | 9.33e-02 |
| PI 3K CASCADE FGFR2 | 16 | 2.85e-01 | -0.154000 | 5.93e-01 |
| RHOBTB1 GTPASE CYCLE | 23 | 2.00e-01 | -0.154000 | 5.08e-01 |
| ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION | 34 | 1.20e-01 | 0.154000 | 4.01e-01 |
| NEURONAL SYSTEM | 369 | 3.99e-07 | -0.154000 | 7.89e-05 |
| GOLGI TO ER RETROGRADE TRANSPORT | 119 | 4.06e-03 | 0.153000 | 4.64e-02 |
| ELEVATION OF CYTOSOLIC CA2 LEVELS | 16 | 2.91e-01 | 0.153000 | 5.95e-01 |
| ANTIMICROBIAL PEPTIDES | 18 | 2.63e-01 | 0.152000 | 5.74e-01 |
| TRAFFICKING OF AMPA RECEPTORS | 31 | 1.42e-01 | -0.152000 | 4.37e-01 |
| INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | 34 | 1.25e-01 | -0.152000 | 4.09e-01 |
| TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA | 16 | 2.94e-01 | -0.152000 | 5.95e-01 |
| SIGNALING BY NOTCH4 | 83 | 1.70e-02 | 0.152000 | 1.16e-01 |
| MUSCLE CONTRACTION | 162 | 8.76e-04 | -0.152000 | 1.52e-02 |
| HDR THROUGH SINGLE STRAND ANNEALING SSA | 36 | 1.16e-01 | -0.151000 | 3.98e-01 |
| GLYCOGEN METABOLISM | 25 | 1.92e-01 | 0.151000 | 4.96e-01 |
| TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX | 14 | 3.29e-01 | 0.151000 | 6.26e-01 |
| MITOCHONDRIAL FATTY ACID BETA OXIDATION | 34 | 1.29e-01 | 0.150000 | 4.23e-01 |
| METABOLISM OF CARBOHYDRATES | 258 | 3.90e-05 | 0.149000 | 1.77e-03 |
| PROTEIN LOCALIZATION | 156 | 1.41e-03 | 0.148000 | 2.22e-02 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 | 25 | 2.00e-01 | -0.148000 | 5.08e-01 |
| NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 2.91e-01 | -0.148000 | 5.95e-01 |
| COMMON PATHWAY OF FIBRIN CLOT FORMATION | 11 | 3.95e-01 | -0.148000 | 6.85e-01 |
| DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | 26 | 1.92e-01 | -0.148000 | 4.95e-01 |
| PLATELET HOMEOSTASIS | 79 | 2.31e-02 | -0.148000 | 1.43e-01 |
| ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM | 12 | 3.75e-01 | 0.148000 | 6.72e-01 |
| CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE | 49 | 7.50e-02 | 0.147000 | 3.08e-01 |
| BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS | 12 | 3.81e-01 | -0.146000 | 6.73e-01 |
| INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS | 35 | 1.35e-01 | -0.146000 | 4.27e-01 |
| ANTIGEN PROCESSING CROSS PRESENTATION | 97 | 1.33e-02 | 0.146000 | 1.02e-01 |
| NUCLEAR ENVELOPE NE REASSEMBLY | 64 | 4.41e-02 | 0.146000 | 2.22e-01 |
| INFLAMMASOMES | 19 | 2.73e-01 | 0.145000 | 5.86e-01 |
| MATURATION OF SARS COV 2 SPIKE PROTEIN | 29 | 1.78e-01 | 0.145000 | 4.82e-01 |
| SUPPRESSION OF PHAGOSOMAL MATURATION | 12 | 3.86e-01 | 0.145000 | 6.76e-01 |
| RAC1 GTPASE CYCLE | 178 | 9.46e-04 | -0.144000 | 1.61e-02 |
| PLASMA LIPOPROTEIN ASSEMBLY | 13 | 3.69e-01 | 0.144000 | 6.66e-01 |
| SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA | 42 | 1.08e-01 | 0.143000 | 3.82e-01 |
| ASSEMBLY OF THE PRE REPLICATIVE COMPLEX | 64 | 4.81e-02 | 0.143000 | 2.29e-01 |
| REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | 29 | 1.84e-01 | -0.142000 | 4.89e-01 |
| TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA | 34 | 1.51e-01 | -0.142000 | 4.45e-01 |
| PHOSPHORYLATION OF THE APC C | 17 | 3.10e-01 | 0.142000 | 6.10e-01 |
| PROCESSING OF INTRONLESS PRE MRNAS | 19 | 2.85e-01 | -0.142000 | 5.93e-01 |
| YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | 11 | 4.17e-01 | 0.141000 | 6.98e-01 |
| DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | 23 | 2.41e-01 | -0.141000 | 5.51e-01 |
| PEPTIDE LIGAND BINDING RECEPTORS | 118 | 8.27e-03 | 0.141000 | 7.44e-02 |
| RHOU GTPASE CYCLE | 33 | 1.63e-01 | -0.141000 | 4.63e-01 |
| ERK MAPK TARGETS | 22 | 2.54e-01 | -0.140000 | 5.62e-01 |
| DISEASES OF DNA REPAIR | 11 | 4.22e-01 | 0.140000 | 7.03e-01 |
| MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION | 16 | 3.33e-01 | 0.140000 | 6.26e-01 |
| VEGFR2 MEDIATED VASCULAR PERMEABILITY | 27 | 2.10e-01 | -0.139000 | 5.17e-01 |
| SUMOYLATION OF IMMUNE RESPONSE PROTEINS | 11 | 4.23e-01 | 0.139000 | 7.05e-01 |
| SCAVENGING BY CLASS A RECEPTORS | 14 | 3.69e-01 | 0.139000 | 6.66e-01 |
| ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS | 17 | 3.22e-01 | -0.139000 | 6.20e-01 |
| OVARIAN TUMOR DOMAIN PROTEASES | 36 | 1.50e-01 | -0.139000 | 4.45e-01 |
| REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | 91 | 2.26e-02 | 0.138000 | 1.41e-01 |
| CIRCADIAN CLOCK | 68 | 4.91e-02 | -0.138000 | 2.32e-01 |
| SIGNALING BY EGFR IN CANCER | 22 | 2.63e-01 | -0.138000 | 5.74e-01 |
| P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 12 | 4.10e-01 | -0.137000 | 6.98e-01 |
| HYALURONAN UPTAKE AND DEGRADATION | 11 | 4.30e-01 | 0.137000 | 7.10e-01 |
| PLATELET CALCIUM HOMEOSTASIS | 27 | 2.17e-01 | -0.137000 | 5.26e-01 |
| REGULATION OF RUNX1 EXPRESSION AND ACTIVITY | 17 | 3.27e-01 | -0.137000 | 6.26e-01 |
| ERYTHROPOIETIN ACTIVATES RAS | 13 | 3.93e-01 | -0.137000 | 6.84e-01 |
| NETRIN 1 SIGNALING | 49 | 9.83e-02 | -0.137000 | 3.64e-01 |
| INWARDLY RECTIFYING K CHANNELS | 32 | 1.81e-01 | -0.137000 | 4.85e-01 |
| ER TO GOLGI ANTEROGRADE TRANSPORT | 142 | 5.10e-03 | 0.136000 | 5.48e-02 |
| GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK | 17 | 3.32e-01 | -0.136000 | 6.26e-01 |
| CYTOPROTECTION BY HMOX1 | 119 | 1.06e-02 | 0.136000 | 9.12e-02 |
| RRNA PROCESSING IN THE MITOCHONDRION | 10 | 4.58e-01 | 0.136000 | 7.33e-01 |
| GLYCOGEN SYNTHESIS | 14 | 3.80e-01 | 0.136000 | 6.73e-01 |
| INTERLEUKIN 7 SIGNALING | 19 | 3.08e-01 | 0.135000 | 6.06e-01 |
| SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | 14 | 3.81e-01 | 0.135000 | 6.73e-01 |
| DNA DAMAGE RECOGNITION IN GG NER | 38 | 1.50e-01 | 0.135000 | 4.45e-01 |
| SIGNALING BY TGF BETA RECEPTOR COMPLEX | 72 | 4.79e-02 | -0.135000 | 2.29e-01 |
| DNA REPLICATION PRE INITIATION | 79 | 3.83e-02 | 0.135000 | 2.08e-01 |
| PROCESSING OF SMDT1 | 16 | 3.52e-01 | 0.134000 | 6.50e-01 |
| BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS | 32 | 1.88e-01 | 0.134000 | 4.90e-01 |
| GLUCOSE METABOLISM | 80 | 3.83e-02 | 0.134000 | 2.08e-01 |
| CD28 DEPENDENT VAV1 PATHWAY | 11 | 4.43e-01 | -0.134000 | 7.17e-01 |
| PRE NOTCH PROCESSING IN GOLGI | 17 | 3.42e-01 | 0.133000 | 6.37e-01 |
| MICRORNA MIRNA BIOGENESIS | 24 | 2.61e-01 | 0.133000 | 5.72e-01 |
| PINK1 PRKN MEDIATED MITOPHAGY | 22 | 2.83e-01 | 0.132000 | 5.92e-01 |
| PI 3K CASCADE FGFR4 | 12 | 4.29e-01 | -0.132000 | 7.10e-01 |
| SIGNALING BY FGFR2 IIIA TM | 19 | 3.20e-01 | 0.132000 | 6.20e-01 |
| INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | 29 | 2.21e-01 | 0.131000 | 5.31e-01 |
| SPRY REGULATION OF FGF SIGNALING | 16 | 3.63e-01 | 0.131000 | 6.59e-01 |
| DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | 79 | 4.50e-02 | 0.131000 | 2.24e-01 |
| PI 3K CASCADE FGFR3 | 13 | 4.15e-01 | -0.131000 | 6.98e-01 |
| PROTEIN PROTEIN INTERACTIONS AT SYNAPSES | 85 | 3.78e-02 | -0.130000 | 2.08e-01 |
| FCGR3A MEDIATED IL10 SYNTHESIS | 32 | 2.02e-01 | -0.130000 | 5.08e-01 |
| CRISTAE FORMATION | 31 | 2.11e-01 | 0.130000 | 5.18e-01 |
| POLO LIKE KINASE MEDIATED EVENTS | 14 | 4.02e-01 | 0.129000 | 6.92e-01 |
| EPHRIN SIGNALING | 19 | 3.30e-01 | 0.129000 | 6.26e-01 |
| CLASS B 2 SECRETIN FAMILY RECEPTORS | 70 | 6.21e-02 | 0.129000 | 2.76e-01 |
| NEGATIVE REGULATION OF THE PI3K AKT NETWORK | 94 | 3.08e-02 | -0.129000 | 1.77e-01 |
| TELOMERE MAINTENANCE | 80 | 4.63e-02 | 0.129000 | 2.26e-01 |
| CELLULAR RESPONSE TO CHEMICAL STRESS | 151 | 6.60e-03 | 0.128000 | 6.54e-02 |
| GOLGI ASSOCIATED VESICLE BIOGENESIS | 54 | 1.04e-01 | -0.128000 | 3.77e-01 |
| ACYL CHAIN REMODELLING OF PE | 16 | 3.80e-01 | -0.127000 | 6.73e-01 |
| ORC1 REMOVAL FROM CHROMATIN | 67 | 7.35e-02 | 0.126000 | 3.05e-01 |
| ABC FAMILY PROTEINS MEDIATED TRANSPORT | 94 | 3.49e-02 | 0.126000 | 1.97e-01 |
| RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 59 | 9.62e-02 | 0.125000 | 3.60e-01 |
| FGFR2 MUTANT RECEPTOR ACTIVATION | 26 | 2.69e-01 | 0.125000 | 5.82e-01 |
| SEPARATION OF SISTER CHROMATIDS | 166 | 5.51e-03 | 0.125000 | 5.69e-02 |
| LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME | 13 | 4.35e-01 | -0.125000 | 7.10e-01 |
| SIGNALING BY ERBB2 | 48 | 1.34e-01 | -0.125000 | 4.27e-01 |
| DEFECTS IN VITAMIN AND COFACTOR METABOLISM | 21 | 3.22e-01 | 0.125000 | 6.20e-01 |
| ACTIVATION OF BH3 ONLY PROTEINS | 30 | 2.39e-01 | -0.124000 | 5.51e-01 |
| SIGNALING BY ROBO RECEPTORS | 205 | 2.25e-03 | 0.124000 | 3.12e-02 |
| TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | 172 | 5.31e-03 | 0.123000 | 5.64e-02 |
| TRANSCRIPTIONAL REGULATION BY RUNX3 | 92 | 4.13e-02 | 0.123000 | 2.17e-01 |
| TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | 17 | 3.80e-01 | -0.123000 | 6.73e-01 |
| PURINE SALVAGE | 12 | 4.61e-01 | 0.123000 | 7.36e-01 |
| CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | 48 | 1.42e-01 | 0.123000 | 4.37e-01 |
| SYNTHESIS OF PA | 29 | 2.54e-01 | 0.122000 | 5.62e-01 |
| TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS | 12 | 4.63e-01 | -0.122000 | 7.36e-01 |
| COSTIMULATION BY THE CD28 FAMILY | 50 | 1.35e-01 | -0.122000 | 4.27e-01 |
| FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | 18 | 3.70e-01 | 0.122000 | 6.66e-01 |
| RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION | 22 | 3.22e-01 | -0.122000 | 6.20e-01 |
| BASE EXCISION REPAIR | 58 | 1.09e-01 | 0.122000 | 3.83e-01 |
| TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX | 30 | 2.49e-01 | 0.122000 | 5.57e-01 |
| DEREGULATED CDK5 TRIGGERS MULTIPLE NEURODEGENERATIVE PATHWAYS IN ALZHEIMER S DISEASE MODELS | 19 | 3.58e-01 | 0.122000 | 6.54e-01 |
| SIGNALING BY FLT3 ITD AND TKD MUTANTS | 16 | 4.00e-01 | -0.121000 | 6.90e-01 |
| INSULIN RECEPTOR SIGNALLING CASCADE | 44 | 1.65e-01 | -0.121000 | 4.66e-01 |
| RHOF GTPASE CYCLE | 40 | 1.85e-01 | -0.121000 | 4.89e-01 |
| ACTIVATION OF MATRIX METALLOPROTEINASES | 14 | 4.34e-01 | -0.121000 | 7.10e-01 |
| REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS | 12 | 4.69e-01 | -0.121000 | 7.37e-01 |
| SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | 18 | 3.78e-01 | -0.120000 | 6.73e-01 |
| G PROTEIN BETA GAMMA SIGNALLING | 31 | 2.48e-01 | -0.120000 | 5.57e-01 |
| NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 23 | 3.20e-01 | -0.120000 | 6.20e-01 |
| TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | 11 | 4.92e-01 | -0.120000 | 7.56e-01 |
| RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY | 15 | 4.24e-01 | 0.119000 | 7.05e-01 |
| METABOLISM OF AMINE DERIVED HORMONES | 10 | 5.14e-01 | 0.119000 | 7.70e-01 |
| METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION | 15 | 4.24e-01 | -0.119000 | 7.05e-01 |
| SIGNALING BY TGFB FAMILY MEMBERS | 97 | 4.31e-02 | -0.119000 | 2.22e-01 |
| GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER | 24 | 3.14e-01 | 0.119000 | 6.15e-01 |
| SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | 11 | 4.96e-01 | 0.119000 | 7.58e-01 |
| PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE | 52 | 1.39e-01 | 0.119000 | 4.35e-01 |
| GLYCOLYSIS | 66 | 9.61e-02 | 0.119000 | 3.60e-01 |
| IRS MEDIATED SIGNALLING | 39 | 2.01e-01 | -0.118000 | 5.08e-01 |
| DEFECTS IN COBALAMIN B12 METABOLISM | 13 | 4.61e-01 | 0.118000 | 7.36e-01 |
| APOPTOTIC EXECUTION PHASE | 45 | 1.72e-01 | -0.118000 | 4.71e-01 |
| FORMATION OF FIBRIN CLOT CLOTTING CASCADE | 21 | 3.51e-01 | -0.118000 | 6.49e-01 |
| POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION | 26 | 3.00e-01 | -0.117000 | 6.01e-01 |
| REGULATION OF IFNG SIGNALING | 13 | 4.65e-01 | 0.117000 | 7.36e-01 |
| REGULATION OF FZD BY UBIQUITINATION | 20 | 3.65e-01 | 0.117000 | 6.61e-01 |
| DNA REPLICATION | 121 | 2.64e-02 | 0.117000 | 1.57e-01 |
| KSRP KHSRP BINDS AND DESTABILIZES MRNA | 16 | 4.19e-01 | 0.117000 | 7.02e-01 |
| TRANSMISSION ACROSS CHEMICAL SYNAPSES | 241 | 1.90e-03 | -0.116000 | 2.80e-02 |
| SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE | 86 | 6.48e-02 | 0.115000 | 2.79e-01 |
| INFLUENZA INFECTION | 145 | 1.68e-02 | 0.115000 | 1.16e-01 |
| NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 | 11 | 5.09e-01 | -0.115000 | 7.64e-01 |
| METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS | 11 | 5.09e-01 | 0.115000 | 7.64e-01 |
| CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER | 61 | 1.22e-01 | -0.115000 | 4.03e-01 |
| MHC CLASS II ANTIGEN PRESENTATION | 102 | 4.59e-02 | 0.114000 | 2.26e-01 |
| NUCLEAR ENVELOPE BREAKDOWN | 49 | 1.67e-01 | -0.114000 | 4.66e-01 |
| TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | 32 | 2.64e-01 | -0.114000 | 5.74e-01 |
| CLEC7A DECTIN 1 SIGNALING | 95 | 5.53e-02 | 0.114000 | 2.50e-01 |
| FORMATION OF INCISION COMPLEX IN GG NER | 43 | 1.97e-01 | -0.114000 | 5.03e-01 |
| SIGNALING BY KIT IN DISEASE | 20 | 3.80e-01 | -0.113000 | 6.73e-01 |
| EPHB MEDIATED FORWARD SIGNALING | 42 | 2.05e-01 | -0.113000 | 5.10e-01 |
| FORMATION OF TC NER PRE INCISION COMPLEX | 53 | 1.55e-01 | 0.113000 | 4.51e-01 |
| RNA POLYMERASE I TRANSCRIPTION | 69 | 1.05e-01 | 0.113000 | 3.77e-01 |
| REGULATION OF RUNX2 EXPRESSION AND ACTIVITY | 69 | 1.06e-01 | 0.113000 | 3.77e-01 |
| TELOMERE EXTENSION BY TELOMERASE | 22 | 3.62e-01 | 0.112000 | 6.58e-01 |
| ATF6 ATF6 ALPHA ACTIVATES CHAPERONES | 12 | 5.02e-01 | 0.112000 | 7.63e-01 |
| RHOBTB GTPASE CYCLE | 35 | 2.52e-01 | -0.112000 | 5.61e-01 |
| TNF SIGNALING | 43 | 2.04e-01 | 0.112000 | 5.09e-01 |
| METHYLATION | 12 | 5.05e-01 | 0.111000 | 7.63e-01 |
| ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES | 52 | 1.66e-01 | 0.111000 | 4.66e-01 |
| LAMININ INTERACTIONS | 29 | 3.03e-01 | -0.111000 | 6.04e-01 |
| NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION | 180 | 1.06e-02 | -0.111000 | 9.12e-02 |
| REPRESSION OF WNT TARGET GENES | 14 | 4.75e-01 | 0.110000 | 7.42e-01 |
| CELL JUNCTION ORGANIZATION | 73 | 1.03e-01 | -0.110000 | 3.76e-01 |
| INTERLEUKIN 1 FAMILY SIGNALING | 121 | 3.61e-02 | 0.110000 | 2.01e-01 |
| GLYCOSPHINGOLIPID METABOLISM | 38 | 2.40e-01 | 0.110000 | 5.51e-01 |
| SYNAPTIC ADHESION LIKE MOLECULES | 21 | 3.83e-01 | 0.110000 | 6.73e-01 |
| SUMOYLATION OF TRANSCRIPTION FACTORS | 17 | 4.34e-01 | -0.110000 | 7.10e-01 |
| RNA POLYMERASE I TRANSCRIPTION INITIATION | 47 | 1.94e-01 | 0.109000 | 4.98e-01 |
| SIALIC ACID METABOLISM | 32 | 2.84e-01 | -0.109000 | 5.93e-01 |
| ASPARAGINE N LINKED GLYCOSYLATION | 286 | 1.50e-03 | 0.109000 | 2.29e-02 |
| SLC TRANSPORTER DISORDERS | 76 | 9.98e-02 | -0.109000 | 3.68e-01 |
| TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | 13 | 4.96e-01 | -0.109000 | 7.58e-01 |
| N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | 35 | 2.65e-01 | 0.109000 | 5.74e-01 |
| FORMATION OF APOPTOSOME | 10 | 5.51e-01 | -0.109000 | 7.88e-01 |
| SUMOYLATION OF DNA METHYLATION PROTEINS | 16 | 4.51e-01 | -0.109000 | 7.27e-01 |
| RETINOID CYCLE DISEASE EVENTS | 10 | 5.52e-01 | 0.109000 | 7.88e-01 |
| PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE | 19 | 4.12e-01 | 0.109000 | 6.98e-01 |
| COLLAGEN CHAIN TRIMERIZATION | 40 | 2.35e-01 | 0.108000 | 5.46e-01 |
| CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS | 19 | 4.14e-01 | -0.108000 | 6.98e-01 |
| PI 3K CASCADE FGFR1 | 15 | 4.69e-01 | -0.108000 | 7.37e-01 |
| CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY | 22 | 3.82e-01 | -0.108000 | 6.73e-01 |
| NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 12 | 5.20e-01 | -0.107000 | 7.74e-01 |
| PHASE I FUNCTIONALIZATION OF COMPOUNDS | 62 | 1.44e-01 | 0.107000 | 4.39e-01 |
| ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA | 15 | 4.73e-01 | -0.107000 | 7.40e-01 |
| METABOLISM OF RNA | 644 | 4.15e-06 | 0.107000 | 3.77e-04 |
| PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING | 11 | 5.40e-01 | -0.107000 | 7.82e-01 |
| APOPTOTIC FACTOR MEDIATED RESPONSE | 18 | 4.33e-01 | -0.107000 | 7.10e-01 |
| LGI ADAM INTERACTIONS | 14 | 4.90e-01 | -0.107000 | 7.56e-01 |
| RHOV GTPASE CYCLE | 32 | 2.97e-01 | -0.107000 | 5.98e-01 |
| MAPK6 MAPK4 SIGNALING | 83 | 9.34e-02 | 0.107000 | 3.54e-01 |
| REGULATION OF BETA CELL DEVELOPMENT | 28 | 3.33e-01 | -0.106000 | 6.26e-01 |
| MITOTIC METAPHASE AND ANAPHASE | 207 | 8.87e-03 | 0.106000 | 7.86e-02 |
| DISEASES OF PROGRAMMED CELL DEATH | 56 | 1.72e-01 | 0.106000 | 4.71e-01 |
| VXPX CARGO TARGETING TO CILIUM | 19 | 4.27e-01 | 0.105000 | 7.09e-01 |
| NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX | 32 | 3.04e-01 | -0.105000 | 6.05e-01 |
| MITOTIC G2 G2 M PHASES | 184 | 1.43e-02 | 0.105000 | 1.07e-01 |
| PLATELET ADHESION TO EXPOSED COLLAGEN | 12 | 5.30e-01 | -0.105000 | 7.78e-01 |
| RETROGRADE NEUROTROPHIN SIGNALLING | 14 | 4.99e-01 | 0.104000 | 7.61e-01 |
| METABOLISM OF NUCLEOTIDES | 92 | 8.38e-02 | 0.104000 | 3.27e-01 |
| NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING | 33 | 3.01e-01 | -0.104000 | 6.01e-01 |
| CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX | 10 | 5.70e-01 | -0.104000 | 8.01e-01 |
| POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | 58 | 1.72e-01 | -0.104000 | 4.71e-01 |
| RNA POLYMERASE I TRANSCRIPTION TERMINATION | 31 | 3.19e-01 | 0.103000 | 6.20e-01 |
| CELL CELL COMMUNICATION | 106 | 6.62e-02 | -0.103000 | 2.83e-01 |
| FATTY ACYL COA BIOSYNTHESIS | 32 | 3.12e-01 | -0.103000 | 6.13e-01 |
| CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA | 59 | 1.72e-01 | 0.103000 | 4.71e-01 |
| MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | 15 | 4.91e-01 | -0.103000 | 7.56e-01 |
| RHO GTPASES ACTIVATE PAKS | 21 | 4.16e-01 | -0.103000 | 6.98e-01 |
| SUMOYLATION | 165 | 2.44e-02 | -0.102000 | 1.49e-01 |
| SUMOYLATION OF DNA REPLICATION PROTEINS | 43 | 2.50e-01 | -0.101000 | 5.60e-01 |
| STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS | 10 | 5.79e-01 | 0.101000 | 8.05e-01 |
| DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA | 63 | 1.65e-01 | -0.101000 | 4.66e-01 |
| VISUAL PHOTOTRANSDUCTION | 63 | 1.66e-01 | 0.101000 | 4.66e-01 |
| POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 64 | 1.66e-01 | 0.100000 | 4.66e-01 |
| RHOG GTPASE CYCLE | 73 | 1.39e-01 | -0.100000 | 4.35e-01 |
| EXTENSION OF TELOMERES | 49 | 2.26e-01 | 0.100000 | 5.36e-01 |
| ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | 32 | 3.27e-01 | 0.100000 | 6.26e-01 |
| TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST | 13 | 5.33e-01 | -0.100000 | 7.79e-01 |
| TBC RABGAPS | 43 | 2.58e-01 | 0.099600 | 5.69e-01 |
| RNA POLYMERASE III TRANSCRIPTION TERMINATION | 23 | 4.09e-01 | 0.099500 | 6.98e-01 |
| SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX | 12 | 5.52e-01 | 0.099100 | 7.88e-01 |
| MITOPHAGY | 29 | 3.56e-01 | 0.099000 | 6.54e-01 |
| THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT | 172 | 2.52e-02 | 0.099000 | 1.53e-01 |
| GLUTATHIONE CONJUGATION | 29 | 3.57e-01 | 0.098800 | 6.54e-01 |
| PTEN REGULATION | 133 | 4.96e-02 | 0.098700 | 2.32e-01 |
| P75NTR RECRUITS SIGNALLING COMPLEXES | 13 | 5.38e-01 | 0.098600 | 7.81e-01 |
| GPVI MEDIATED ACTIVATION CASCADE | 31 | 3.44e-01 | -0.098300 | 6.39e-01 |
| INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | 13 | 5.40e-01 | 0.098200 | 7.82e-01 |
| HIV TRANSCRIPTION ELONGATION | 42 | 2.71e-01 | 0.098100 | 5.85e-01 |
| REGULATION OF TLR BY ENDOGENOUS LIGAND | 12 | 5.56e-01 | -0.098100 | 7.90e-01 |
| TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | 10 | 5.91e-01 | -0.098100 | 8.15e-01 |
| MRNA SPLICING | 188 | 2.06e-02 | 0.098000 | 1.34e-01 |
| RHOD GTPASE CYCLE | 50 | 2.32e-01 | -0.097800 | 5.42e-01 |
| ION TRANSPORT BY P TYPE ATPASES | 49 | 2.39e-01 | -0.097300 | 5.51e-01 |
| CELLULAR HEXOSE TRANSPORT | 11 | 5.78e-01 | 0.096800 | 8.05e-01 |
| TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 43 | 2.74e-01 | 0.096400 | 5.87e-01 |
| PRC2 METHYLATES HISTONES AND DNA | 31 | 3.54e-01 | 0.096200 | 6.52e-01 |
| O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS | 35 | 3.26e-01 | -0.096000 | 6.24e-01 |
| CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | 89 | 1.18e-01 | -0.095900 | 3.98e-01 |
| SIGNALING BY NODAL | 15 | 5.22e-01 | -0.095400 | 7.75e-01 |
| TRANSCRIPTIONAL REGULATION BY E2F6 | 34 | 3.37e-01 | -0.095100 | 6.30e-01 |
| EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION | 27 | 3.94e-01 | -0.094800 | 6.84e-01 |
| SIGNALING BY ACTIVIN | 12 | 5.71e-01 | -0.094400 | 8.02e-01 |
| INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | 19 | 4.76e-01 | 0.094400 | 7.44e-01 |
| TELOMERE C STRAND SYNTHESIS INITIATION | 13 | 5.59e-01 | 0.093700 | 7.92e-01 |
| ADENYLATE CYCLASE ACTIVATING PATHWAY | 10 | 6.09e-01 | -0.093400 | 8.21e-01 |
| METABOLISM OF COFACTORS | 19 | 4.83e-01 | 0.092900 | 7.52e-01 |
| TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS | 41 | 3.05e-01 | -0.092700 | 6.05e-01 |
| FORMATION OF RNA POL II ELONGATION COMPLEX | 57 | 2.26e-01 | 0.092600 | 5.37e-01 |
| SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS | 11 | 5.97e-01 | -0.092100 | 8.16e-01 |
| SIGNALING BY ERBB4 | 57 | 2.31e-01 | -0.091800 | 5.41e-01 |
| CS DS DEGRADATION | 14 | 5.53e-01 | 0.091500 | 7.88e-01 |
| HCMV INFECTION | 105 | 1.06e-01 | 0.091400 | 3.77e-01 |
| TELOMERE C STRAND LAGGING STRAND SYNTHESIS | 33 | 3.64e-01 | 0.091300 | 6.60e-01 |
| HYALURONAN METABOLISM | 15 | 5.42e-01 | 0.090800 | 7.84e-01 |
| TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | 16 | 5.30e-01 | 0.090700 | 7.78e-01 |
| RND1 GTPASE CYCLE | 38 | 3.35e-01 | -0.090500 | 6.27e-01 |
| G ALPHA I SIGNALLING EVENTS | 206 | 2.60e-02 | -0.090100 | 1.55e-01 |
| RHOB GTPASE CYCLE | 67 | 2.03e-01 | -0.090100 | 5.08e-01 |
| NEGATIVE REGULATION OF FGFR4 SIGNALING | 23 | 4.56e-01 | 0.089800 | 7.31e-01 |
| IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | 10 | 6.24e-01 | -0.089500 | 8.26e-01 |
| IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX | 10 | 6.25e-01 | 0.089200 | 8.26e-01 |
| RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | 28 | 4.14e-01 | 0.089100 | 6.98e-01 |
| TRIGLYCERIDE CATABOLISM | 14 | 5.64e-01 | -0.089000 | 7.96e-01 |
| G BETA GAMMA SIGNALLING THROUGH CDC42 | 19 | 5.04e-01 | -0.088700 | 7.63e-01 |
| CD28 CO STIMULATION | 31 | 3.93e-01 | -0.088700 | 6.84e-01 |
| SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R | 45 | 3.08e-01 | -0.087900 | 6.06e-01 |
| STIMULI SENSING CHANNELS | 76 | 1.85e-01 | -0.087900 | 4.89e-01 |
| ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION | 27 | 4.29e-01 | 0.087900 | 7.10e-01 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 | 23 | 4.66e-01 | -0.087900 | 7.37e-01 |
| TCF DEPENDENT SIGNALING IN RESPONSE TO WNT | 179 | 4.29e-02 | 0.087800 | 2.22e-01 |
| CELL EXTRACELLULAR MATRIX INTERACTIONS | 18 | 5.21e-01 | 0.087400 | 7.75e-01 |
| PROTEIN METHYLATION | 17 | 5.33e-01 | 0.087400 | 7.79e-01 |
| BIOLOGICAL OXIDATIONS | 127 | 9.21e-02 | 0.086600 | 3.50e-01 |
| CELLULAR RESPONSES TO EXTERNAL STIMULI | 604 | 2.96e-04 | 0.086600 | 7.27e-03 |
| METABOLISM OF VITAMINS AND COFACTORS | 156 | 6.29e-02 | 0.086400 | 2.77e-01 |
| TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS | 69 | 2.15e-01 | -0.086300 | 5.25e-01 |
| AMYLOID FIBER FORMATION | 60 | 2.48e-01 | 0.086300 | 5.57e-01 |
| SIGNALING BY SCF KIT | 41 | 3.39e-01 | -0.086200 | 6.33e-01 |
| MEIOTIC RECOMBINATION | 40 | 3.45e-01 | -0.086200 | 6.41e-01 |
| ORGANELLE BIOGENESIS AND MAINTENANCE | 283 | 1.27e-02 | 0.086200 | 1.01e-01 |
| PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR | 20 | 5.05e-01 | 0.086200 | 7.63e-01 |
| CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 | 11 | 6.22e-01 | -0.086000 | 8.25e-01 |
| ADENYLATE CYCLASE INHIBITORY PATHWAY | 13 | 5.95e-01 | -0.085300 | 8.16e-01 |
| DEADENYLATION DEPENDENT MRNA DECAY | 55 | 2.74e-01 | -0.085200 | 5.87e-01 |
| HCMV EARLY EVENTS | 82 | 1.83e-01 | 0.085100 | 4.87e-01 |
| ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS | 10 | 6.44e-01 | -0.084500 | 8.34e-01 |
| HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | 10 | 6.44e-01 | -0.084500 | 8.34e-01 |
| G2 M DNA DAMAGE CHECKPOINT | 66 | 2.35e-01 | -0.084500 | 5.46e-01 |
| INTERLEUKIN 27 SIGNALING | 10 | 6.44e-01 | -0.084500 | 8.34e-01 |
| GENERATION OF SECOND MESSENGER MOLECULES | 19 | 5.26e-01 | -0.084000 | 7.77e-01 |
| TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER | 77 | 2.03e-01 | 0.083900 | 5.08e-01 |
| UPTAKE AND ACTIONS OF BACTERIAL TOXINS | 29 | 4.35e-01 | -0.083900 | 7.10e-01 |
| MEIOSIS | 66 | 2.41e-01 | -0.083600 | 5.51e-01 |
| CYCLIN D ASSOCIATED EVENTS IN G1 | 45 | 3.32e-01 | -0.083600 | 6.26e-01 |
| GROWTH HORMONE RECEPTOR SIGNALING | 20 | 5.18e-01 | 0.083500 | 7.73e-01 |
| METABOLISM OF STEROIDS | 116 | 1.21e-01 | 0.083500 | 4.02e-01 |
| REGULATION OF LIPID METABOLISM BY PPARALPHA | 108 | 1.35e-01 | -0.083300 | 4.27e-01 |
| REPRODUCTION | 79 | 2.01e-01 | -0.083200 | 5.08e-01 |
| RNA POLYMERASE III TRANSCRIPTION | 41 | 3.57e-01 | 0.083100 | 6.54e-01 |
| FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES | 15 | 5.78e-01 | -0.083000 | 8.05e-01 |
| SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX | 13 | 6.05e-01 | 0.082700 | 8.21e-01 |
| GLUCAGON TYPE LIGAND RECEPTORS | 26 | 4.67e-01 | 0.082400 | 7.37e-01 |
| ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | 23 | 4.94e-01 | 0.082400 | 7.58e-01 |
| TCR SIGNALING | 100 | 1.55e-01 | 0.082300 | 4.51e-01 |
| INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC | 185 | 5.46e-02 | 0.082000 | 2.50e-01 |
| BRANCHED CHAIN AMINO ACID CATABOLISM | 21 | 5.16e-01 | 0.081800 | 7.72e-01 |
| BETA CATENIN INDEPENDENT WNT SIGNALING | 139 | 9.61e-02 | 0.081800 | 3.60e-01 |
| SIGNALING BY FGFR1 | 43 | 3.56e-01 | -0.081400 | 6.54e-01 |
| NEGATIVE REGULATION OF FGFR3 SIGNALING | 24 | 4.90e-01 | 0.081300 | 7.56e-01 |
| TRNA PROCESSING IN THE NUCLEUS | 56 | 2.93e-01 | -0.081200 | 5.95e-01 |
| ESR MEDIATED SIGNALING | 169 | 6.91e-02 | -0.081100 | 2.91e-01 |
| FERTILIZATION | 13 | 6.14e-01 | -0.080700 | 8.21e-01 |
| INITIATION OF NUCLEAR ENVELOPE NE REFORMATION | 17 | 5.66e-01 | 0.080400 | 7.97e-01 |
| NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION | 59 | 2.91e-01 | -0.079500 | 5.95e-01 |
| RNA POLYMERASE II TRANSCRIPTION | 1090 | 1.11e-05 | -0.079400 | 6.91e-04 |
| INTERLEUKIN 6 FAMILY SIGNALING | 20 | 5.41e-01 | 0.078900 | 7.83e-01 |
| RAS PROCESSING | 24 | 5.03e-01 | 0.078900 | 7.63e-01 |
| FLT3 SIGNALING | 36 | 4.16e-01 | -0.078400 | 6.98e-01 |
| TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | 86 | 2.09e-01 | -0.078300 | 5.17e-01 |
| IRAK1 RECRUITS IKK COMPLEX | 14 | 6.12e-01 | 0.078200 | 8.21e-01 |
| NEGATIVE REGULATION OF FGFR1 SIGNALING | 26 | 4.91e-01 | 0.078000 | 7.56e-01 |
| COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM | 14 | 6.13e-01 | 0.078000 | 8.21e-01 |
| PI3K AKT SIGNALING IN CANCER | 88 | 2.10e-01 | -0.077400 | 5.17e-01 |
| SIGNALING BY FGFR2 | 63 | 2.89e-01 | 0.077300 | 5.95e-01 |
| G1 S SPECIFIC TRANSCRIPTION | 26 | 4.96e-01 | 0.077200 | 7.58e-01 |
| NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS | 20 | 5.54e-01 | 0.076500 | 7.88e-01 |
| NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 67 | 2.79e-01 | 0.076500 | 5.91e-01 |
| RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | 85 | 2.25e-01 | 0.076200 | 5.36e-01 |
| ELASTIC FIBRE FORMATION | 38 | 4.17e-01 | 0.076100 | 6.98e-01 |
| UNWINDING OF DNA | 12 | 6.49e-01 | -0.075800 | 8.37e-01 |
| ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS | 83 | 2.33e-01 | -0.075800 | 5.43e-01 |
| GLYCEROPHOSPHOLIPID BIOSYNTHESIS | 107 | 1.81e-01 | 0.074900 | 4.85e-01 |
| LYSOSOME VESICLE BIOGENESIS | 32 | 4.64e-01 | 0.074800 | 7.36e-01 |
| RESOLUTION OF ABASIC SITES AP SITES | 37 | 4.33e-01 | 0.074500 | 7.10e-01 |
| GABA B RECEPTOR ACTIVATION | 40 | 4.15e-01 | -0.074500 | 6.98e-01 |
| SEMA3A PAK DEPENDENT AXON REPULSION | 16 | 6.06e-01 | -0.074400 | 8.21e-01 |
| LYSINE CATABOLISM | 11 | 6.71e-01 | 0.073900 | 8.54e-01 |
| AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS | 10 | 6.88e-01 | -0.073400 | 8.59e-01 |
| RNA POLYMERASE I PROMOTER ESCAPE | 49 | 3.76e-01 | 0.073100 | 6.72e-01 |
| PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | 17 | 6.03e-01 | 0.072900 | 8.21e-01 |
| NEGATIVE REGULATION OF FLT3 | 14 | 6.39e-01 | 0.072400 | 8.33e-01 |
| TNFR1 INDUCED PROAPOPTOTIC SIGNALING | 12 | 6.64e-01 | 0.072400 | 8.49e-01 |
| NICOTINATE METABOLISM | 25 | 5.31e-01 | -0.072400 | 7.78e-01 |
| CRMPS IN SEMA3A SIGNALING | 16 | 6.16e-01 | 0.072300 | 8.21e-01 |
| RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN | 37 | 4.47e-01 | -0.072300 | 7.21e-01 |
| PKMTS METHYLATE HISTONE LYSINES | 49 | 3.82e-01 | -0.072300 | 6.73e-01 |
| HOST INTERACTIONS OF HIV FACTORS | 124 | 1.67e-01 | 0.072000 | 4.66e-01 |
| FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX | 48 | 3.89e-01 | 0.071800 | 6.80e-01 |
| SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | 62 | 3.28e-01 | 0.071800 | 6.26e-01 |
| DNA DAMAGE BYPASS | 46 | 4.00e-01 | -0.071800 | 6.90e-01 |
| PEROXISOMAL PROTEIN IMPORT | 57 | 3.49e-01 | 0.071800 | 6.46e-01 |
| SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION | 26 | 5.28e-01 | 0.071500 | 7.78e-01 |
| CALNEXIN CALRETICULIN CYCLE | 26 | 5.29e-01 | 0.071400 | 7.78e-01 |
| NONHOMOLOGOUS END JOINING NHEJ | 44 | 4.14e-01 | -0.071200 | 6.98e-01 |
| SIGNAL TRANSDUCTION BY L1 | 21 | 5.74e-01 | -0.070800 | 8.03e-01 |
| DNA STRAND ELONGATION | 32 | 4.88e-01 | 0.070800 | 7.56e-01 |
| EGFR DOWNREGULATION | 28 | 5.18e-01 | -0.070600 | 7.73e-01 |
| ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS | 19 | 5.95e-01 | 0.070500 | 8.16e-01 |
| DETOXIFICATION OF REACTIVE OXYGEN SPECIES | 33 | 4.85e-01 | 0.070200 | 7.53e-01 |
| RHO GTPASE CYCLE | 426 | 1.33e-02 | -0.070200 | 1.02e-01 |
| TOLL LIKE RECEPTOR CASCADES | 137 | 1.58e-01 | -0.070000 | 4.54e-01 |
| P38MAPK EVENTS | 12 | 6.75e-01 | 0.069900 | 8.54e-01 |
| ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 | 23 | 5.62e-01 | 0.069900 | 7.94e-01 |
| CYTOKINE SIGNALING IN IMMUNE SYSTEM | 541 | 5.59e-03 | -0.069900 | 5.73e-02 |
| SUMOYLATION OF TRANSCRIPTION COFACTORS | 42 | 4.33e-01 | -0.069900 | 7.10e-01 |
| TOLL LIKE RECEPTOR 9 TLR9 CASCADE | 90 | 2.54e-01 | -0.069600 | 5.62e-01 |
| NEDDYLATION | 219 | 7.67e-02 | 0.069500 | 3.10e-01 |
| NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | 45 | 4.20e-01 | 0.069500 | 7.02e-01 |
| SARS COV 1 INFECTION | 48 | 4.06e-01 | 0.069400 | 6.95e-01 |
| O LINKED GLYCOSYLATION OF MUCINS | 41 | 4.44e-01 | 0.069100 | 7.19e-01 |
| TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS | 11 | 6.95e-01 | -0.068300 | 8.61e-01 |
| INSULIN RECEPTOR RECYCLING | 20 | 5.97e-01 | 0.068200 | 8.16e-01 |
| C TYPE LECTIN RECEPTORS CLRS | 113 | 2.11e-01 | 0.068100 | 5.18e-01 |
| WNT LIGAND BIOGENESIS AND TRAFFICKING | 20 | 6.00e-01 | 0.067700 | 8.19e-01 |
| B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION | 49 | 4.14e-01 | 0.067500 | 6.98e-01 |
| SPHINGOLIPID DE NOVO BIOSYNTHESIS | 42 | 4.54e-01 | -0.066800 | 7.29e-01 |
| NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | 13 | 6.77e-01 | 0.066600 | 8.54e-01 |
| PLASMA LIPOPROTEIN REMODELING | 17 | 6.35e-01 | 0.066600 | 8.31e-01 |
| RHOBTB2 GTPASE CYCLE | 23 | 5.82e-01 | -0.066300 | 8.09e-01 |
| SIGNALING BY EGFR | 47 | 4.35e-01 | -0.065800 | 7.10e-01 |
| G ALPHA Z SIGNALLING EVENTS | 46 | 4.40e-01 | -0.065800 | 7.15e-01 |
| GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION | 12 | 6.93e-01 | 0.065800 | 8.61e-01 |
| UPTAKE AND FUNCTION OF ANTHRAX TOXINS | 11 | 7.06e-01 | 0.065700 | 8.65e-01 |
| INTRINSIC PATHWAY FOR APOPTOSIS | 52 | 4.13e-01 | -0.065600 | 6.98e-01 |
| INTERLEUKIN 17 SIGNALING | 67 | 3.54e-01 | -0.065600 | 6.52e-01 |
| SARS COV 2 INFECTION | 65 | 3.64e-01 | 0.065200 | 6.59e-01 |
| EXTRACELLULAR MATRIX ORGANIZATION | 243 | 8.14e-02 | 0.065000 | 3.22e-01 |
| MITOCHONDRIAL BIOGENESIS | 92 | 2.82e-01 | -0.065000 | 5.92e-01 |
| IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | 48 | 4.38e-01 | -0.064700 | 7.13e-01 |
| CHROMOSOME MAINTENANCE | 103 | 2.59e-01 | 0.064500 | 5.69e-01 |
| RND2 GTPASE CYCLE | 38 | 4.93e-01 | -0.064300 | 7.56e-01 |
| MITOTIC PROPHASE | 96 | 2.77e-01 | -0.064300 | 5.89e-01 |
| SIGNALING BY NOTCH3 | 48 | 4.42e-01 | -0.064200 | 7.16e-01 |
| MRNA CAPPING | 29 | 5.50e-01 | 0.064200 | 7.88e-01 |
| SIGNALING BY NOTCH | 189 | 1.30e-01 | 0.064000 | 4.23e-01 |
| ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES | 10 | 7.27e-01 | -0.063800 | 8.78e-01 |
| PEROXISOMAL LIPID METABOLISM | 26 | 5.74e-01 | 0.063700 | 8.03e-01 |
| MITOTIC G1 PHASE AND G1 S TRANSITION | 141 | 1.93e-01 | 0.063600 | 4.96e-01 |
| ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION | 95 | 2.87e-01 | 0.063300 | 5.95e-01 |
| RECEPTOR MEDIATED MITOPHAGY | 11 | 7.17e-01 | -0.063100 | 8.70e-01 |
| CDC42 GTPASE CYCLE | 153 | 1.79e-01 | -0.063000 | 4.85e-01 |
| OTHER INTERLEUKIN SIGNALING | 20 | 6.26e-01 | 0.062900 | 8.26e-01 |
| INTERLEUKIN 37 SIGNALING | 18 | 6.45e-01 | 0.062700 | 8.35e-01 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 | 20 | 6.29e-01 | -0.062400 | 8.29e-01 |
| HDR THROUGH HOMOLOGOUS RECOMBINATION HRR | 62 | 3.97e-01 | -0.062300 | 6.86e-01 |
| NR1H2 AND NR1H3 MEDIATED SIGNALING | 38 | 5.07e-01 | -0.062300 | 7.64e-01 |
| SIGNALLING TO ERKS | 33 | 5.36e-01 | -0.062300 | 7.80e-01 |
| REGULATION OF KIT SIGNALING | 16 | 6.67e-01 | -0.062100 | 8.50e-01 |
| ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS | 23 | 6.06e-01 | 0.062100 | 8.21e-01 |
| CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND | 12 | 7.10e-01 | -0.062000 | 8.68e-01 |
| BASIGIN INTERACTIONS | 22 | 6.15e-01 | -0.062000 | 8.21e-01 |
| RHOC GTPASE CYCLE | 73 | 3.61e-01 | -0.061900 | 6.57e-01 |
| NUCLEAR SIGNALING BY ERBB4 | 31 | 5.53e-01 | 0.061600 | 7.88e-01 |
| NEUTROPHIL DEGRANULATION | 386 | 3.82e-02 | 0.061600 | 2.08e-01 |
| SIGNALING BY NOTCH2 | 32 | 5.47e-01 | -0.061600 | 7.88e-01 |
| ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE | 96 | 3.01e-01 | 0.061100 | 6.01e-01 |
| SLC MEDIATED TRANSMEMBRANE TRANSPORT | 192 | 1.45e-01 | -0.061100 | 4.39e-01 |
| REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION | 30 | 5.63e-01 | 0.061000 | 7.95e-01 |
| MAP2K AND MAPK ACTIVATION | 36 | 5.27e-01 | -0.061000 | 7.77e-01 |
| TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX | 18 | 6.54e-01 | 0.061000 | 8.40e-01 |
| TRANSCRIPTIONAL REGULATION BY RUNX2 | 108 | 2.75e-01 | 0.060800 | 5.88e-01 |
| INTERLEUKIN 35 SIGNALLING | 10 | 7.39e-01 | -0.060800 | 8.87e-01 |
| E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS | 51 | 4.53e-01 | -0.060700 | 7.29e-01 |
| RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK | 48 | 4.67e-01 | -0.060700 | 7.37e-01 |
| THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | 23 | 6.15e-01 | 0.060600 | 8.21e-01 |
| G PROTEIN ACTIVATION | 23 | 6.15e-01 | 0.060600 | 8.21e-01 |
| TRANSFERRIN ENDOCYTOSIS AND RECYCLING | 26 | 5.94e-01 | 0.060500 | 8.16e-01 |
| INTERLEUKIN 2 FAMILY SIGNALING | 33 | 5.50e-01 | -0.060100 | 7.88e-01 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 | 19 | 6.52e-01 | -0.059700 | 8.40e-01 |
| TRIGLYCERIDE BIOSYNTHESIS | 10 | 7.46e-01 | 0.059100 | 8.92e-01 |
| THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | 29 | 5.83e-01 | 0.058900 | 8.09e-01 |
| AMINO ACIDS REGULATE MTORC1 | 51 | 4.67e-01 | 0.058800 | 7.37e-01 |
| ERKS ARE INACTIVATED | 13 | 7.14e-01 | -0.058700 | 8.70e-01 |
| NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS | 52 | 4.65e-01 | 0.058600 | 7.36e-01 |
| PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | 237 | 1.21e-01 | 0.058500 | 4.03e-01 |
| NRAGE SIGNALS DEATH THROUGH JNK | 55 | 4.55e-01 | -0.058300 | 7.29e-01 |
| HIV INFECTION | 220 | 1.37e-01 | 0.058300 | 4.32e-01 |
| SURFACTANT METABOLISM | 16 | 6.87e-01 | 0.058100 | 8.59e-01 |
| SIGNALING BY THE B CELL RECEPTOR BCR | 104 | 3.06e-01 | 0.058100 | 6.06e-01 |
| NEPHRIN FAMILY INTERACTIONS | 23 | 6.30e-01 | -0.058000 | 8.29e-01 |
| TRANSLESION SYNTHESIS BY POLK | 17 | 6.80e-01 | -0.057700 | 8.54e-01 |
| SARS COV INFECTIONS | 140 | 2.40e-01 | 0.057600 | 5.51e-01 |
| ABC TRANSPORTERS IN LIPID HOMEOSTASIS | 14 | 7.11e-01 | -0.057200 | 8.69e-01 |
| BILE ACID AND BILE SALT METABOLISM | 25 | 6.21e-01 | -0.057100 | 8.25e-01 |
| AQUAPORIN MEDIATED TRANSPORT | 40 | 5.36e-01 | -0.056600 | 7.80e-01 |
| INOSITOL PHOSPHATE METABOLISM | 47 | 5.02e-01 | -0.056600 | 7.63e-01 |
| RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | 106 | 3.17e-01 | 0.056300 | 6.19e-01 |
| AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | 14 | 7.17e-01 | 0.055900 | 8.70e-01 |
| SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL | 26 | 6.23e-01 | -0.055600 | 8.26e-01 |
| HOMOLOGY DIRECTED REPAIR | 107 | 3.21e-01 | -0.055500 | 6.20e-01 |
| REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR | 10 | 7.61e-01 | 0.055500 | 8.96e-01 |
| G2 M CHECKPOINTS | 133 | 2.70e-01 | 0.055400 | 5.83e-01 |
| REGULATION OF TP53 EXPRESSION AND DEGRADATION | 34 | 5.76e-01 | 0.055400 | 8.04e-01 |
| DISEASES OF IMMUNE SYSTEM | 24 | 6.40e-01 | -0.055100 | 8.33e-01 |
| GPCR LIGAND BINDING | 281 | 1.13e-01 | 0.055000 | 3.92e-01 |
| SIGNALING BY BRAF AND RAF FUSIONS | 60 | 4.62e-01 | -0.054900 | 7.36e-01 |
| RUNX2 REGULATES BONE DEVELOPMENT | 28 | 6.16e-01 | -0.054800 | 8.21e-01 |
| REGULATION OF SIGNALING BY CBL | 22 | 6.57e-01 | -0.054600 | 8.43e-01 |
| SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES | 29 | 6.11e-01 | -0.054500 | 8.21e-01 |
| EPH EPHRIN MEDIATED REPULSION OF CELLS | 51 | 5.13e-01 | -0.052900 | 7.70e-01 |
| ION CHANNEL TRANSPORT | 142 | 2.79e-01 | -0.052700 | 5.91e-01 |
| EPH EPHRIN SIGNALING | 92 | 3.85e-01 | -0.052400 | 6.76e-01 |
| SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS | 41 | 5.61e-01 | -0.052400 | 7.94e-01 |
| FGFR2 LIGAND BINDING AND ACTIVATION | 12 | 7.54e-01 | 0.052200 | 8.94e-01 |
| TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE | 93 | 3.86e-01 | -0.052000 | 6.76e-01 |
| SIGNALING BY WNT IN CANCER | 31 | 6.17e-01 | -0.052000 | 8.21e-01 |
| MITOCHONDRIAL CALCIUM ION TRANSPORT | 23 | 6.67e-01 | 0.051800 | 8.50e-01 |
| IRON UPTAKE AND TRANSPORT | 51 | 5.23e-01 | 0.051700 | 7.75e-01 |
| MOLECULES ASSOCIATED WITH ELASTIC FIBRES | 32 | 6.14e-01 | 0.051500 | 8.21e-01 |
| UB SPECIFIC PROCESSING PROTEASES | 168 | 2.52e-01 | 0.051300 | 5.61e-01 |
| TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS | 28 | 6.40e-01 | 0.051000 | 8.33e-01 |
| SIGNALING BY NUCLEAR RECEPTORS | 225 | 1.88e-01 | -0.051000 | 4.90e-01 |
| JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | 22 | 6.81e-01 | -0.050600 | 8.54e-01 |
| SIGNALING BY NTRKS | 130 | 3.21e-01 | -0.050500 | 6.20e-01 |
| SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER | 15 | 7.36e-01 | 0.050200 | 8.87e-01 |
| TRANSCRIPTIONAL REGULATION BY RUNX1 | 179 | 2.48e-01 | 0.050100 | 5.57e-01 |
| NOTCH HLH TRANSCRIPTION PATHWAY | 28 | 6.48e-01 | 0.049900 | 8.37e-01 |
| SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | 31 | 6.31e-01 | -0.049800 | 8.30e-01 |
| PROTEIN UBIQUITINATION | 70 | 4.72e-01 | -0.049700 | 7.40e-01 |
| INFECTIOUS DISEASE | 737 | 2.24e-02 | 0.049700 | 1.41e-01 |
| DEGRADATION OF THE EXTRACELLULAR MATRIX | 107 | 3.76e-01 | 0.049600 | 6.72e-01 |
| TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS | 44 | 5.70e-01 | 0.049500 | 8.01e-01 |
| FATTY ACID METABOLISM | 145 | 3.05e-01 | 0.049400 | 6.05e-01 |
| S PHASE | 153 | 2.94e-01 | 0.049300 | 5.95e-01 |
| ACYL CHAIN REMODELLING OF PC | 16 | 7.34e-01 | -0.049000 | 8.85e-01 |
| ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 | 10 | 7.89e-01 | 0.048900 | 9.14e-01 |
| SIGNALING BY INSULIN RECEPTOR | 63 | 5.07e-01 | -0.048400 | 7.64e-01 |
| ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | 25 | 6.77e-01 | -0.048100 | 8.54e-01 |
| ACTIVATION OF GENE EXPRESSION BY SREBF SREBP | 43 | 5.88e-01 | 0.047700 | 8.13e-01 |
| TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | 74 | 4.78e-01 | -0.047700 | 7.45e-01 |
| STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES | 14 | 7.58e-01 | -0.047500 | 8.94e-01 |
| MEIOTIC SYNAPSIS | 42 | 5.96e-01 | 0.047300 | 8.16e-01 |
| BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | 76 | 4.77e-01 | 0.047200 | 7.44e-01 |
| TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT | 18 | 7.30e-01 | -0.047100 | 8.80e-01 |
| LEISHMANIA INFECTION | 201 | 2.52e-01 | -0.047000 | 5.61e-01 |
| EPIGENETIC REGULATION OF GENE EXPRESSION | 105 | 4.06e-01 | 0.046900 | 6.95e-01 |
| VITAMIN B5 PANTOTHENATE METABOLISM | 15 | 7.54e-01 | -0.046800 | 8.94e-01 |
| IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | 20 | 7.17e-01 | 0.046800 | 8.70e-01 |
| COMPLEMENT CASCADE | 25 | 6.86e-01 | 0.046800 | 8.59e-01 |
| NICOTINAMIDE SALVAGING | 16 | 7.47e-01 | -0.046500 | 8.92e-01 |
| PROCESSING OF DNA DOUBLE STRAND BREAK ENDS | 71 | 5.00e-01 | -0.046300 | 7.61e-01 |
| CLASS A 1 RHODOPSIN LIKE RECEPTORS | 199 | 2.64e-01 | 0.046000 | 5.74e-01 |
| RNA POLYMERASE II TRANSCRIPTION TERMINATION | 65 | 5.22e-01 | 0.045900 | 7.75e-01 |
| IRF3 MEDIATED INDUCTION OF TYPE I IFN | 11 | 7.92e-01 | 0.045800 | 9.17e-01 |
| METALLOPROTEASE DUBS | 27 | 6.81e-01 | 0.045800 | 8.54e-01 |
| ONCOGENIC MAPK SIGNALING | 77 | 4.89e-01 | -0.045600 | 7.56e-01 |
| SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | 12 | 7.85e-01 | -0.045500 | 9.14e-01 |
| CHONDROITIN SULFATE BIOSYNTHESIS | 18 | 7.40e-01 | 0.045100 | 8.87e-01 |
| TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE | 63 | 5.36e-01 | 0.045000 | 7.80e-01 |
| ONCOGENE INDUCED SENESCENCE | 32 | 6.60e-01 | 0.045000 | 8.45e-01 |
| TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | 31 | 6.66e-01 | -0.044900 | 8.50e-01 |
| PHASE II CONJUGATION OF COMPOUNDS | 62 | 5.47e-01 | 0.044200 | 7.88e-01 |
| TERMINATION OF TRANSLESION DNA SYNTHESIS | 30 | 6.76e-01 | -0.044100 | 8.54e-01 |
| STRIATED MUSCLE CONTRACTION | 25 | 7.04e-01 | -0.043900 | 8.64e-01 |
| NEGATIVE REGULATION OF FGFR2 SIGNALING | 27 | 6.95e-01 | 0.043700 | 8.61e-01 |
| DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS | 51 | 5.93e-01 | 0.043300 | 8.16e-01 |
| ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING | 29 | 6.87e-01 | -0.043300 | 8.59e-01 |
| P75 NTR RECEPTOR MEDIATED SIGNALLING | 94 | 4.69e-01 | -0.043200 | 7.37e-01 |
| SYNDECAN INTERACTIONS | 27 | 6.99e-01 | 0.043100 | 8.64e-01 |
| DUAL INCISION IN TC NER | 64 | 5.54e-01 | 0.042800 | 7.88e-01 |
| SIGNALING BY RECEPTOR TYROSINE KINASES | 467 | 1.17e-01 | -0.042500 | 3.98e-01 |
| PROCESSING OF CAPPED INTRONLESS PRE MRNA | 28 | 7.03e-01 | -0.041700 | 8.64e-01 |
| SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 | 13 | 7.95e-01 | -0.041600 | 9.17e-01 |
| MET PROMOTES CELL MOTILITY | 39 | 6.54e-01 | -0.041500 | 8.40e-01 |
| REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS | 12 | 8.04e-01 | 0.041300 | 9.18e-01 |
| COLLAGEN DEGRADATION | 51 | 6.11e-01 | 0.041200 | 8.21e-01 |
| ACYL CHAIN REMODELLING OF PG | 10 | 8.22e-01 | -0.041100 | 9.26e-01 |
| DISORDERS OF TRANSMEMBRANE TRANSPORTERS | 146 | 3.94e-01 | 0.040900 | 6.84e-01 |
| DERMATAN SULFATE BIOSYNTHESIS | 11 | 8.14e-01 | 0.040900 | 9.22e-01 |
| POTENTIAL THERAPEUTICS FOR SARS | 77 | 5.36e-01 | 0.040900 | 7.80e-01 |
| SIGNALING BY RETINOIC ACID | 32 | 6.89e-01 | 0.040800 | 8.60e-01 |
| NEGATIVE REGULATION OF MET ACTIVITY | 20 | 7.53e-01 | 0.040600 | 8.94e-01 |
| CELLULAR SENESCENCE | 144 | 4.05e-01 | 0.040200 | 6.95e-01 |
| HEMOSTASIS | 473 | 1.37e-01 | -0.040100 | 4.32e-01 |
| RND3 GTPASE CYCLE | 37 | 6.73e-01 | -0.040100 | 8.54e-01 |
| NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | 17 | 7.76e-01 | -0.039900 | 9.05e-01 |
| PROGRAMMED CELL DEATH | 185 | 3.58e-01 | 0.039300 | 6.54e-01 |
| SIGNALLING TO RAS | 19 | 7.68e-01 | 0.039000 | 9.01e-01 |
| NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 20 | 7.64e-01 | -0.038800 | 8.98e-01 |
| TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | 13 | 8.10e-01 | -0.038600 | 9.20e-01 |
| PENTOSE PHOSPHATE PATHWAY | 13 | 8.10e-01 | 0.038500 | 9.20e-01 |
| RHO GTPASE EFFECTORS | 253 | 2.93e-01 | -0.038500 | 5.95e-01 |
| ACYL CHAIN REMODELLING OF PS | 14 | 8.05e-01 | 0.038200 | 9.18e-01 |
| APOPTOSIS | 163 | 4.03e-01 | 0.038000 | 6.92e-01 |
| DNA DOUBLE STRAND BREAK REPAIR | 136 | 4.47e-01 | -0.037800 | 7.21e-01 |
| M PHASE | 342 | 2.33e-01 | 0.037600 | 5.43e-01 |
| ESTROGEN DEPENDENT GENE EXPRESSION | 105 | 5.07e-01 | -0.037500 | 7.64e-01 |
| NUCLEOBASE BIOSYNTHESIS | 15 | 8.02e-01 | 0.037300 | 9.18e-01 |
| RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY | 24 | 7.52e-01 | 0.037300 | 8.94e-01 |
| SIGNALING BY GPCR | 497 | 1.58e-01 | -0.037100 | 4.56e-01 |
| VIRAL MESSENGER RNA SYNTHESIS | 42 | 6.78e-01 | -0.037000 | 8.54e-01 |
| NUCLEOBASE CATABOLISM | 31 | 7.23e-01 | 0.036800 | 8.76e-01 |
| SENSORY PROCESSING OF SOUND | 62 | 6.17e-01 | 0.036700 | 8.21e-01 |
| DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE | 26 | 7.47e-01 | 0.036600 | 8.92e-01 |
| NGF STIMULATED TRANSCRIPTION | 37 | 7.01e-01 | -0.036500 | 8.64e-01 |
| TRANSCRIPTION OF THE HIV GENOME | 67 | 6.08e-01 | 0.036300 | 8.21e-01 |
| AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | 28 | 7.40e-01 | -0.036200 | 8.87e-01 |
| CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | 73 | 5.96e-01 | -0.035900 | 8.16e-01 |
| ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 | 20 | 7.83e-01 | -0.035600 | 9.13e-01 |
| NON INTEGRIN MEMBRANE ECM INTERACTIONS | 57 | 6.43e-01 | 0.035500 | 8.34e-01 |
| FRS MEDIATED FGFR4 SIGNALING | 14 | 8.19e-01 | 0.035400 | 9.23e-01 |
| NUCLEOTIDE EXCISION REPAIR | 109 | 5.24e-01 | 0.035400 | 7.75e-01 |
| REGULATION OF INSULIN SECRETION | 72 | 6.05e-01 | -0.035200 | 8.21e-01 |
| GLUCAGON SIGNALING IN METABOLIC REGULATION | 30 | 7.39e-01 | 0.035100 | 8.87e-01 |
| TP53 REGULATES METABOLIC GENES | 85 | 5.76e-01 | -0.035100 | 8.04e-01 |
| DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS | 17 | 8.02e-01 | 0.035000 | 9.18e-01 |
| TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE | 37 | 7.13e-01 | -0.035000 | 8.69e-01 |
| TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE | 19 | 7.92e-01 | 0.035000 | 9.17e-01 |
| PKA ACTIVATION IN GLUCAGON SIGNALLING | 16 | 8.09e-01 | 0.034900 | 9.20e-01 |
| SIGNALING BY FGFR | 74 | 6.05e-01 | 0.034800 | 8.21e-01 |
| PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS | 20 | 7.88e-01 | -0.034800 | 9.14e-01 |
| RESOLUTION OF SISTER CHROMATID COHESION | 102 | 5.48e-01 | 0.034400 | 7.88e-01 |
| TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS | 46 | 6.91e-01 | 0.033900 | 8.61e-01 |
| REGULATED PROTEOLYSIS OF P75NTR | 12 | 8.39e-01 | -0.033800 | 9.36e-01 |
| SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 | 631 | 1.49e-01 | -0.033800 | 4.45e-01 |
| MET ACTIVATES PTK2 SIGNALING | 29 | 7.55e-01 | 0.033400 | 8.94e-01 |
| TRANS GOLGI NETWORK VESICLE BUDDING | 69 | 6.33e-01 | -0.033300 | 8.30e-01 |
| RIPK1 MEDIATED REGULATED NECROSIS | 25 | 7.74e-01 | 0.033200 | 9.04e-01 |
| CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER | 26 | 7.72e-01 | 0.032800 | 9.04e-01 |
| TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES | 45 | 7.03e-01 | -0.032800 | 8.64e-01 |
| KETONE BODY METABOLISM | 10 | 8.60e-01 | 0.032300 | 9.43e-01 |
| NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 48 | 7.00e-01 | -0.032200 | 8.64e-01 |
| SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | 15 | 8.30e-01 | 0.032000 | 9.33e-01 |
| PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 | 11 | 8.56e-01 | 0.031700 | 9.42e-01 |
| TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 | 15 | 8.32e-01 | -0.031500 | 9.33e-01 |
| TRANSCRIPTIONAL REGULATION BY VENTX | 35 | 7.48e-01 | 0.031300 | 8.92e-01 |
| INTEGRIN CELL SURFACE INTERACTIONS | 71 | 6.49e-01 | -0.031300 | 8.37e-01 |
| ANCHORING FIBRIL FORMATION | 14 | 8.40e-01 | 0.031100 | 9.37e-01 |
| GP1B IX V ACTIVATION SIGNALLING | 10 | 8.65e-01 | -0.031000 | 9.43e-01 |
| OXIDATIVE STRESS INDUCED SENESCENCE | 80 | 6.33e-01 | 0.030900 | 8.30e-01 |
| LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS | 20 | 8.13e-01 | -0.030600 | 9.22e-01 |
| NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 23 | 8.04e-01 | 0.029900 | 9.18e-01 |
| CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION | 22 | 8.09e-01 | 0.029800 | 9.20e-01 |
| SNRNP ASSEMBLY | 51 | 7.13e-01 | -0.029800 | 8.69e-01 |
| ECM PROTEOGLYCANS | 67 | 6.76e-01 | 0.029600 | 8.54e-01 |
| VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS | 37 | 7.59e-01 | -0.029200 | 8.94e-01 |
| SIGNALING BY PDGF | 57 | 7.03e-01 | 0.029200 | 8.64e-01 |
| SIGNALING BY FGFR IN DISEASE | 55 | 7.08e-01 | -0.029200 | 8.67e-01 |
| REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION | 87 | 6.39e-01 | -0.029100 | 8.33e-01 |
| RHOH GTPASE CYCLE | 37 | 7.61e-01 | -0.028900 | 8.96e-01 |
| FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | 118 | 5.89e-01 | 0.028800 | 8.13e-01 |
| ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK | 28 | 7.94e-01 | -0.028500 | 9.17e-01 |
| COPII MEDIATED VESICLE TRANSPORT | 66 | 6.94e-01 | 0.028000 | 8.61e-01 |
| TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES | 37 | 7.68e-01 | -0.028000 | 9.01e-01 |
| NEGATIVE REGULATION OF MAPK PATHWAY | 42 | 7.55e-01 | 0.027900 | 8.94e-01 |
| G ALPHA 12 13 SIGNALLING EVENTS | 75 | 6.77e-01 | -0.027800 | 8.54e-01 |
| INTRA GOLGI TRAFFIC | 43 | 7.56e-01 | -0.027400 | 8.94e-01 |
| RHOA GTPASE CYCLE | 142 | 5.74e-01 | -0.027400 | 8.03e-01 |
| TRIGLYCERIDE METABOLISM | 24 | 8.17e-01 | -0.027300 | 9.22e-01 |
| INTERLEUKIN 15 SIGNALING | 12 | 8.70e-01 | -0.027300 | 9.47e-01 |
| SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER | 59 | 7.17e-01 | -0.027300 | 8.70e-01 |
| O LINKED GLYCOSYLATION | 85 | 6.67e-01 | 0.027000 | 8.50e-01 |
| FRS MEDIATED FGFR1 SIGNALING | 17 | 8.47e-01 | 0.027000 | 9.38e-01 |
| ROS AND RNS PRODUCTION IN PHAGOCYTES | 29 | 8.02e-01 | 0.026900 | 9.18e-01 |
| INTRACELLULAR SIGNALING BY SECOND MESSENGERS | 281 | 4.40e-01 | -0.026800 | 7.15e-01 |
| DOWNSTREAM SIGNAL TRANSDUCTION | 29 | 8.03e-01 | -0.026800 | 9.18e-01 |
| VESICLE MEDIATED TRANSPORT | 611 | 2.60e-01 | 0.026800 | 5.70e-01 |
| INTEGRATION OF ENERGY METABOLISM | 99 | 6.47e-01 | 0.026600 | 8.37e-01 |
| GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION | 25 | 8.18e-01 | 0.026600 | 9.23e-01 |
| BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA | 16 | 8.56e-01 | -0.026200 | 9.42e-01 |
| DEATH RECEPTOR SIGNALLING | 133 | 6.10e-01 | -0.025700 | 8.21e-01 |
| FRS MEDIATED FGFR3 SIGNALING | 15 | 8.64e-01 | 0.025500 | 9.43e-01 |
| RAB GEFS EXCHANGE GTP FOR GDP ON RABS | 88 | 6.80e-01 | -0.025400 | 8.54e-01 |
| METABOLISM OF PORPHYRINS | 19 | 8.49e-01 | -0.025300 | 9.38e-01 |
| PYRIMIDINE CATABOLISM | 10 | 8.91e-01 | 0.025000 | 9.57e-01 |
| TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX | 11 | 8.87e-01 | -0.024800 | 9.55e-01 |
| INTERLEUKIN RECEPTOR SHC SIGNALING | 20 | 8.48e-01 | -0.024800 | 9.38e-01 |
| PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | 12 | 8.83e-01 | 0.024500 | 9.53e-01 |
| NCAM1 INTERACTIONS | 41 | 7.88e-01 | 0.024200 | 9.14e-01 |
| RAF INDEPENDENT MAPK1 3 ACTIVATION | 21 | 8.50e-01 | 0.023800 | 9.38e-01 |
| REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE | 75 | 7.24e-01 | -0.023600 | 8.76e-01 |
| TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS | 19 | 8.59e-01 | 0.023500 | 9.43e-01 |
| CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS | 94 | 6.95e-01 | -0.023400 | 8.61e-01 |
| PHOSPHOLIPID METABOLISM | 185 | 5.88e-01 | -0.023100 | 8.13e-01 |
| ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION | 120 | 6.64e-01 | 0.023000 | 8.49e-01 |
| RAF ACTIVATION | 34 | 8.17e-01 | -0.023000 | 9.22e-01 |
| THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS | 26 | 8.42e-01 | -0.022600 | 9.37e-01 |
| RHO GTPASES ACTIVATE FORMINS | 119 | 6.72e-01 | 0.022500 | 8.54e-01 |
| RHO GTPASES ACTIVATE KTN1 | 11 | 8.98e-01 | -0.022400 | 9.58e-01 |
| CTLA4 INHIBITORY SIGNALING | 20 | 8.63e-01 | 0.022300 | 9.43e-01 |
| ENDOGENOUS STEROLS | 21 | 8.62e-01 | 0.021900 | 9.43e-01 |
| DNA REPAIR | 292 | 5.22e-01 | 0.021800 | 7.75e-01 |
| PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | 51 | 7.89e-01 | -0.021700 | 9.14e-01 |
| FRS MEDIATED FGFR2 SIGNALING | 18 | 8.73e-01 | -0.021700 | 9.49e-01 |
| SIGNALING BY MET | 75 | 7.47e-01 | 0.021600 | 8.92e-01 |
| MITOTIC PROMETAPHASE | 177 | 6.26e-01 | -0.021200 | 8.26e-01 |
| MYD88 INDEPENDENT TLR4 CASCADE | 92 | 7.25e-01 | -0.021200 | 8.77e-01 |
| NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 26 | 8.52e-01 | 0.021100 | 9.39e-01 |
| SEMAPHORIN INTERACTIONS | 64 | 7.70e-01 | 0.021100 | 9.03e-01 |
| DEPOLYMERISATION OF THE NUCLEAR LAMINA | 13 | 8.96e-01 | 0.021000 | 9.58e-01 |
| SIGNALING BY WNT | 270 | 5.58e-01 | 0.020800 | 7.92e-01 |
| MEMBRANE TRAFFICKING | 581 | 3.99e-01 | 0.020500 | 6.90e-01 |
| CELL CYCLE CHECKPOINTS | 242 | 5.86e-01 | 0.020300 | 8.12e-01 |
| GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | 14 | 8.95e-01 | 0.020300 | 9.58e-01 |
| RET SIGNALING | 37 | 8.34e-01 | -0.020000 | 9.33e-01 |
| PURINE CATABOLISM | 16 | 8.92e-01 | -0.019700 | 9.57e-01 |
| CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION | 347 | 5.31e-01 | -0.019600 | 7.78e-01 |
| DNA DOUBLE STRAND BREAK RESPONSE | 53 | 8.05e-01 | 0.019600 | 9.18e-01 |
| HDACS DEACETYLATE HISTONES | 48 | 8.15e-01 | 0.019600 | 9.22e-01 |
| ADAPTIVE IMMUNE SYSTEM | 601 | 4.15e-01 | -0.019600 | 6.98e-01 |
| NERVOUS SYSTEM DEVELOPMENT | 550 | 4.35e-01 | 0.019500 | 7.10e-01 |
| SMOOTH MUSCLE CONTRACTION | 34 | 8.45e-01 | 0.019400 | 9.38e-01 |
| SUMOYLATION OF INTRACELLULAR RECEPTORS | 27 | 8.62e-01 | -0.019400 | 9.43e-01 |
| CLATHRIN MEDIATED ENDOCYTOSIS | 134 | 7.03e-01 | -0.019100 | 8.64e-01 |
| DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE | 46 | 8.24e-01 | -0.018900 | 9.27e-01 |
| GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION | 39 | 8.38e-01 | -0.018900 | 9.36e-01 |
| CELL CYCLE MITOTIC | 476 | 4.85e-01 | 0.018700 | 7.53e-01 |
| PEPTIDE HORMONE METABOLISM | 61 | 8.01e-01 | -0.018600 | 9.18e-01 |
| RHO GTPASES ACTIVATE CIT | 18 | 8.92e-01 | -0.018400 | 9.57e-01 |
| TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN | 12 | 9.13e-01 | -0.018100 | 9.66e-01 |
| RHO GTPASES ACTIVATE ROCKS | 19 | 8.91e-01 | 0.018100 | 9.57e-01 |
| INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL | 15 | 9.04e-01 | 0.018000 | 9.63e-01 |
| RAB REGULATION OF TRAFFICKING | 119 | 7.38e-01 | 0.017800 | 8.87e-01 |
| G0 AND EARLY G1 | 25 | 8.79e-01 | 0.017700 | 9.53e-01 |
| METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS | 103 | 7.58e-01 | 0.017600 | 8.94e-01 |
| INTEGRIN SIGNALING | 24 | 8.83e-01 | -0.017400 | 9.53e-01 |
| SPHINGOLIPID METABOLISM | 80 | 7.89e-01 | 0.017300 | 9.14e-01 |
| SIGNALING BY PTK6 | 50 | 8.33e-01 | -0.017200 | 9.33e-01 |
| INTERLEUKIN 12 FAMILY SIGNALING | 44 | 8.48e-01 | -0.016800 | 9.38e-01 |
| PYROPTOSIS | 21 | 8.96e-01 | -0.016500 | 9.58e-01 |
| REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF | 56 | 8.31e-01 | 0.016500 | 9.33e-01 |
| INTERLEUKIN 12 SIGNALING | 37 | 8.64e-01 | 0.016300 | 9.43e-01 |
| DISEASES OF MITOTIC CELL CYCLE | 37 | 8.65e-01 | -0.016100 | 9.43e-01 |
| GENE SILENCING BY RNA | 84 | 8.02e-01 | -0.015900 | 9.18e-01 |
| HEME BIOSYNTHESIS | 13 | 9.23e-01 | -0.015600 | 9.70e-01 |
| SIGNALING BY NTRK3 TRKC | 17 | 9.14e-01 | -0.015200 | 9.66e-01 |
| SHC MEDIATED CASCADE FGFR4 | 12 | 9.27e-01 | 0.015200 | 9.73e-01 |
| N GLYCAN ANTENNAE ELONGATION | 15 | 9.20e-01 | -0.015000 | 9.69e-01 |
| APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | 34 | 8.80e-01 | 0.015000 | 9.53e-01 |
| TRANSCRIPTIONAL REGULATION BY TP53 | 340 | 6.37e-01 | -0.014900 | 8.33e-01 |
| REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION | 85 | 8.14e-01 | 0.014700 | 9.22e-01 |
| DOWNREGULATION OF ERBB2 SIGNALING | 28 | 8.94e-01 | -0.014500 | 9.58e-01 |
| L1CAM INTERACTIONS | 109 | 7.97e-01 | -0.014300 | 9.18e-01 |
| SIGNALING BY FGFR2 IN DISEASE | 36 | 8.83e-01 | -0.014200 | 9.53e-01 |
| TRANSLESION SYNTHESIS BY POLH | 19 | 9.15e-01 | 0.014200 | 9.66e-01 |
| DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | 39 | 8.82e-01 | 0.013700 | 9.53e-01 |
| ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | 286 | 6.92e-01 | -0.013700 | 8.61e-01 |
| AURKA ACTIVATION BY TPX2 | 71 | 8.44e-01 | -0.013500 | 9.38e-01 |
| ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS | 68 | 8.50e-01 | 0.013200 | 9.38e-01 |
| PRE NOTCH EXPRESSION AND PROCESSING | 65 | 8.59e-01 | -0.012800 | 9.43e-01 |
| MTORC1 MEDIATED SIGNALLING | 24 | 9.14e-01 | -0.012700 | 9.66e-01 |
| SYNTHESIS OF PC | 26 | 9.11e-01 | 0.012700 | 9.66e-01 |
| PROCESSING AND ACTIVATION OF SUMO | 10 | 9.45e-01 | 0.012500 | 9.81e-01 |
| CELLULAR RESPONSE TO HEAT STRESS | 94 | 8.36e-01 | 0.012400 | 9.35e-01 |
| DUAL INCISION IN GG NER | 40 | 8.97e-01 | 0.011800 | 9.58e-01 |
| TRANSPORT OF SMALL MOLECULES | 583 | 6.38e-01 | -0.011500 | 8.33e-01 |
| CHROMATIN MODIFYING ENZYMES | 220 | 7.73e-01 | -0.011300 | 9.04e-01 |
| PLATELET SENSITIZATION BY LDL | 15 | 9.42e-01 | 0.010800 | 9.80e-01 |
| SIGNALING BY CSF3 G CSF | 29 | 9.21e-01 | 0.010700 | 9.69e-01 |
| REGULATED NECROSIS | 46 | 9.02e-01 | 0.010500 | 9.61e-01 |
| INNATE IMMUNE SYSTEM | 781 | 6.23e-01 | 0.010400 | 8.26e-01 |
| POST TRANSLATIONAL PROTEIN MODIFICATION | 1221 | 5.52e-01 | 0.010200 | 7.88e-01 |
| SIGNALING BY INTERLEUKINS | 345 | 7.54e-01 | 0.009850 | 8.94e-01 |
| INACTIVATION OF CSF3 G CSF SIGNALING | 24 | 9.34e-01 | 0.009790 | 9.76e-01 |
| SHC MEDIATED CASCADE FGFR1 | 15 | 9.48e-01 | 0.009690 | 9.81e-01 |
| HATS ACETYLATE HISTONES | 94 | 8.72e-01 | 0.009650 | 9.48e-01 |
| SIGNALING BY NOTCH1 | 75 | 8.86e-01 | -0.009610 | 9.54e-01 |
| PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION | 23 | 9.37e-01 | 0.009580 | 9.77e-01 |
| ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY | 11 | 9.57e-01 | -0.009420 | 9.86e-01 |
| SIGNAL AMPLIFICATION | 31 | 9.29e-01 | 0.009290 | 9.73e-01 |
| MITOTIC SPINDLE CHECKPOINT | 97 | 8.76e-01 | -0.009180 | 9.51e-01 |
| METABOLISM OF LIPIDS | 616 | 7.04e-01 | 0.009000 | 8.64e-01 |
| SENSORY PERCEPTION | 148 | 8.50e-01 | 0.009000 | 9.38e-01 |
| TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES | 61 | 9.06e-01 | -0.008750 | 9.64e-01 |
| RHO GTPASES ACTIVATE PKNS | 49 | 9.17e-01 | -0.008650 | 9.67e-01 |
| G ALPHA S SIGNALLING EVENTS | 108 | 8.82e-01 | 0.008250 | 9.53e-01 |
| ARACHIDONIC ACID METABOLISM | 38 | 9.30e-01 | -0.008220 | 9.73e-01 |
| HCMV LATE EVENTS | 67 | 9.10e-01 | -0.007990 | 9.66e-01 |
| DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS | 366 | 7.98e-01 | -0.007820 | 9.18e-01 |
| PLATELET ACTIVATION SIGNALING AND AGGREGATION | 224 | 8.43e-01 | -0.007680 | 9.38e-01 |
| INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING | 76 | 9.10e-01 | -0.007490 | 9.66e-01 |
| NOD1 2 SIGNALING PATHWAY | 34 | 9.40e-01 | -0.007440 | 9.79e-01 |
| CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | 34 | 9.40e-01 | 0.007420 | 9.79e-01 |
| RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX | 29 | 9.47e-01 | 0.007100 | 9.81e-01 |
| FLT3 SIGNALING IN DISEASE | 28 | 9.49e-01 | 0.006990 | 9.81e-01 |
| PROLACTIN RECEPTOR SIGNALING | 11 | 9.68e-01 | -0.006960 | 9.91e-01 |
| CARGO CONCENTRATION IN THE ER | 31 | 9.51e-01 | 0.006430 | 9.81e-01 |
| CELL CYCLE | 593 | 7.93e-01 | 0.006330 | 9.17e-01 |
| PLATELET AGGREGATION PLUG FORMATION | 32 | 9.51e-01 | 0.006320 | 9.81e-01 |
| CD28 DEPENDENT PI3K AKT SIGNALING | 21 | 9.61e-01 | -0.006190 | 9.89e-01 |
| SIGNALING BY FGFR3 | 35 | 9.50e-01 | -0.006140 | 9.81e-01 |
| TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | 79 | 9.26e-01 | 0.006050 | 9.73e-01 |
| MTOR SIGNALLING | 40 | 9.48e-01 | 0.006020 | 9.81e-01 |
| RNA POLYMERASE II TRANSCRIBES SNRNA GENES | 74 | 9.30e-01 | -0.005930 | 9.73e-01 |
| TRP CHANNELS | 20 | 9.64e-01 | 0.005850 | 9.89e-01 |
| FC EPSILON RECEPTOR FCERI SIGNALING | 124 | 9.12e-01 | 0.005740 | 9.66e-01 |
| ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS | 22 | 9.63e-01 | -0.005720 | 9.89e-01 |
| CONDENSATION OF PROPHASE CHROMOSOMES | 29 | 9.59e-01 | 0.005510 | 9.88e-01 |
| SHC MEDIATED CASCADE FGFR3 | 13 | 9.74e-01 | 0.005300 | 9.93e-01 |
| RHOBTB3 ATPASE CYCLE | 10 | 9.78e-01 | 0.005060 | 9.94e-01 |
| INCRETIN SYNTHESIS SECRETION AND INACTIVATION | 14 | 9.75e-01 | -0.004870 | 9.93e-01 |
| ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | 11 | 9.78e-01 | 0.004820 | 9.94e-01 |
| RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES | 78 | 9.42e-01 | 0.004730 | 9.80e-01 |
| HIV LIFE CYCLE | 142 | 9.27e-01 | 0.004430 | 9.73e-01 |
| TRANSCRIPTIONAL REGULATION BY SMALL RNAS | 63 | 9.52e-01 | 0.004380 | 9.82e-01 |
| DEUBIQUITINATION | 242 | 9.07e-01 | 0.004360 | 9.64e-01 |
| DEVELOPMENTAL BIOLOGY | 822 | 8.39e-01 | 0.004180 | 9.36e-01 |
| DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX | 41 | 9.63e-01 | 0.004150 | 9.89e-01 |
| IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS | 14 | 9.80e-01 | -0.003810 | 9.94e-01 |
| GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION | 32 | 9.71e-01 | -0.003700 | 9.92e-01 |
| G ALPHA Q SIGNALLING EVENTS | 166 | 9.36e-01 | -0.003630 | 9.77e-01 |
| G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | 24 | 9.76e-01 | -0.003500 | 9.94e-01 |
| RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION | 52 | 9.68e-01 | 0.003220 | 9.91e-01 |
| REGULATION OF PTEN GENE TRANSCRIPTION | 58 | 9.68e-01 | -0.003010 | 9.91e-01 |
| NCAM SIGNALING FOR NEURITE OUT GROWTH | 61 | 9.70e-01 | -0.002830 | 9.91e-01 |
| SYNTHESIS OF BILE ACIDS AND BILE SALTS | 22 | 9.82e-01 | -0.002790 | 9.94e-01 |
| SIGNALING BY FGFR4 | 33 | 9.79e-01 | 0.002710 | 9.94e-01 |
| INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING | 41 | 9.79e-01 | -0.002330 | 9.94e-01 |
| PERK REGULATES GENE EXPRESSION | 28 | 9.84e-01 | -0.002130 | 9.95e-01 |
| INITIAL TRIGGERING OF COMPLEMENT | 11 | 9.91e-01 | 0.002020 | 9.96e-01 |
| ER QUALITY CONTROL COMPARTMENT ERQC | 21 | 9.89e-01 | -0.001690 | 9.96e-01 |
| COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING | 36 | 9.86e-01 | -0.001670 | 9.96e-01 |
| TRAF6 MEDIATED NF KB ACTIVATION | 22 | 9.90e-01 | -0.001530 | 9.96e-01 |
| GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER | 83 | 9.81e-01 | -0.001490 | 9.94e-01 |
| ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY | 10 | 9.94e-01 | 0.001270 | 9.98e-01 |
| TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS | 32 | 9.91e-01 | 0.001170 | 9.96e-01 |
| PHASE 2 PLATEAU PHASE | 12 | 9.94e-01 | 0.001150 | 9.98e-01 |
| MAPK FAMILY SIGNALING CASCADES | 287 | 9.75e-01 | -0.001090 | 9.93e-01 |
| GAP JUNCTION DEGRADATION | 11 | 9.96e-01 | 0.000953 | 9.98e-01 |
| HIV TRANSCRIPTION INITIATION | 45 | 9.91e-01 | 0.000928 | 9.96e-01 |
| REGULATION OF TP53 ACTIVITY | 149 | 9.91e-01 | 0.000549 | 9.96e-01 |
| REGULATION OF BACH1 ACTIVITY | 11 | 9.98e-01 | -0.000453 | 9.98e-01 |
| TRNA PROCESSING | 105 | 9.96e-01 | 0.000292 | 9.98e-01 |
| ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 | 24 | 9.98e-01 | -0.000254 | 9.98e-01 |
Detailed Gene set reports
POST CHAPERONIN TUBULIN FOLDING PATHWAY
| set | POST CHAPERONIN TUBULIN FOLDING PATHWAY |
| setSize | 17 |
| pANOVA | 7.43e-06 |
| s.dist | 0.628 |
| p.adjustANOVA | 0.000567 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Tubb6 | 7443 |
| Tubb3 | 7249 |
| Tubb4a | 7218 |
| Tbcb | 7012 |
| Tubb2b | 6485 |
| Arl2 | 6353 |
| Tuba4a | 5173 |
| Tbcd | 5062 |
| Tuba8 | 4756 |
| Tuba1c | 2963 |
| Tbcc | 2458 |
| Tbca | -1009 |
| Tbce | -3127 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Tubb6 | 7443 |
| Tubb3 | 7249 |
| Tubb4a | 7218 |
| Tbcb | 7012 |
| Tubb2b | 6485 |
| Arl2 | 6353 |
| Tuba4a | 5173 |
| Tbcd | 5062 |
| Tuba8 | 4756 |
| Tuba1c | 2963 |
| Tbcc | 2458 |
| Tbca | -1009 |
| Tbce | -3127 |
TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE
| set | TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE |
| setSize | 13 |
| pANOVA | 0.000228 |
| s.dist | 0.59 |
| p.adjustANOVA | 0.00596 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Tubb6 | 7443 |
| Tubb3 | 7249 |
| Tubb4a | 7218 |
| Tubb2b | 6485 |
| Tuba4a | 5173 |
| Tuba8 | 4756 |
| Tuba1c | 2963 |
| Gjb2 | -4214 |
| Gja1 | -4297 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Tubb6 | 7443 |
| Tubb3 | 7249 |
| Tubb4a | 7218 |
| Tubb2b | 6485 |
| Tuba4a | 5173 |
| Tuba8 | 4756 |
| Tuba1c | 2963 |
| Gjb2 | -4214 |
| Gja1 | -4297 |
FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC
| set | FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC |
| setSize | 19 |
| pANOVA | 1.23e-05 |
| s.dist | 0.579 |
| p.adjustANOVA | 0.000724 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Cct5 | 7963 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Tubb6 | 7443 |
| Cct7 | 7270 |
| Tubb3 | 7249 |
| Cct3 | 7238 |
| Tubb4a | 7218 |
| Tubb2b | 6485 |
| Tuba4a | 5173 |
| Tuba8 | 4756 |
| Cct4 | 3814 |
| Tuba1c | 2963 |
| Cct2 | 622 |
| Cct6a | -2054 |
| Cct8 | -2182 |
| Tcp1 | -3186 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Cct5 | 7963 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Tubb6 | 7443 |
| Cct7 | 7270 |
| Tubb3 | 7249 |
| Cct3 | 7238 |
| Tubb4a | 7218 |
| Tubb2b | 6485 |
| Tuba4a | 5173 |
| Tuba8 | 4756 |
| Cct4 | 3814 |
| Tuba1c | 2963 |
| Cct2 | 622 |
| Cct6a | -2054 |
| Cct8 | -2182 |
| Tcp1 | -3186 |
CGMP EFFECTS
| set | CGMP EFFECTS |
| setSize | 15 |
| pANOVA | 0.000152 |
| s.dist | -0.565 |
| p.adjustANOVA | 0.00461 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Kcnmb2 | -8593 |
| Pde1b | -8174 |
| Pde10a | -8111 |
| Pde1a | -7948 |
| Pde2a | -7424 |
| Itpr1 | -7383 |
| Kcnma1 | -7277 |
| Pde5a | -6734 |
| Prkg1 | -5083 |
| Prkg2 | -4794 |
| Pde11a | -3894 |
| Kcnmb4 | -3826 |
| Irag1 | -1233 |
| Pde9a | 2604 |
| Kcnmb1 | 4571 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Kcnmb2 | -8593 |
| Pde1b | -8174 |
| Pde10a | -8111 |
| Pde1a | -7948 |
| Pde2a | -7424 |
| Itpr1 | -7383 |
| Kcnma1 | -7277 |
| Pde5a | -6734 |
| Prkg1 | -5083 |
| Prkg2 | -4794 |
| Pde11a | -3894 |
| Kcnmb4 | -3826 |
| Irag1 | -1233 |
| Pde9a | 2604 |
| Kcnmb1 | 4571 |
REDUCTION OF CYTOSOLIC CA LEVELS
| set | REDUCTION OF CYTOSOLIC CA LEVELS |
| setSize | 11 |
| pANOVA | 0.00133 |
| s.dist | -0.559 |
| p.adjustANOVA | 0.0212 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Atp2b1 | -8492 |
| Slc8a1 | -8193 |
| Calm1 | -7913 |
| Atp2b4 | -7752 |
| Atp2a3 | -7143 |
| Atp2b2 | -6939 |
| Sri | -6779 |
| Atp2a2 | -4275 |
| Atp2b3 | -1359 |
| Slc8a3 | 1469 |
| Slc8a2 | 4177 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Atp2b1 | -8492 |
| Slc8a1 | -8193 |
| Calm1 | -7913 |
| Atp2b4 | -7752 |
| Atp2a3 | -7143 |
| Atp2b2 | -6939 |
| Sri | -6779 |
| Atp2a2 | -4275 |
| Atp2b3 | -1359 |
| Slc8a3 | 1469 |
| Slc8a2 | 4177 |
NITRIC OXIDE STIMULATES GUANYLATE CYCLASE
| set | NITRIC OXIDE STIMULATES GUANYLATE CYCLASE |
| setSize | 20 |
| pANOVA | 5.97e-05 |
| s.dist | -0.518 |
| p.adjustANOVA | 0.0022 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Kcnmb2 | -8593 |
| Gucy1a1 | -8551 |
| Pde1b | -8174 |
| Pde10a | -8111 |
| Pde1a | -7948 |
| Pde2a | -7424 |
| Itpr1 | -7383 |
| Kcnma1 | -7277 |
| Gucy1b1 | -6900 |
| Pde5a | -6734 |
| Gucy1a2 | -5569 |
| Prkg1 | -5083 |
| Prkg2 | -4794 |
| Pde11a | -3894 |
| Kcnmb4 | -3826 |
| Irag1 | -1233 |
| Nos3 | 1734 |
| Pde9a | 2604 |
| Nos1 | 2805 |
| Kcnmb1 | 4571 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Kcnmb2 | -8593 |
| Gucy1a1 | -8551 |
| Pde1b | -8174 |
| Pde10a | -8111 |
| Pde1a | -7948 |
| Pde2a | -7424 |
| Itpr1 | -7383 |
| Kcnma1 | -7277 |
| Gucy1b1 | -6900 |
| Pde5a | -6734 |
| Gucy1a2 | -5569 |
| Prkg1 | -5083 |
| Prkg2 | -4794 |
| Pde11a | -3894 |
| Kcnmb4 | -3826 |
| Irag1 | -1233 |
| Nos3 | 1734 |
| Pde9a | 2604 |
| Nos1 | 2805 |
| Kcnmb1 | 4571 |
SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III
| set | SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III |
| setSize | 23 |
| pANOVA | 2.23e-05 |
| s.dist | 0.511 |
| p.adjustANOVA | 0.00109 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Lemd2 | 8336 |
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Chmp4b | 7599 |
| Tubb6 | 7443 |
| Tubb3 | 7249 |
| Tubb4a | 7218 |
| Chmp7 | 6852 |
| Tubb2b | 6485 |
| Chmp6 | 6179 |
| Tuba4a | 5173 |
| Tuba8 | 4756 |
| Vps4a | 4515 |
| Cc2d1b | 4246 |
| Chmp2a | 3817 |
| Tuba1c | 2963 |
| Chmp3 | -111 |
| Ist1 | -1821 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Lemd2 | 8336 |
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Chmp4b | 7599 |
| Tubb6 | 7443 |
| Tubb3 | 7249 |
| Tubb4a | 7218 |
| Chmp7 | 6852 |
| Tubb2b | 6485 |
| Chmp6 | 6179 |
| Tuba4a | 5173 |
| Tuba8 | 4756 |
| Vps4a | 4515 |
| Cc2d1b | 4246 |
| Chmp2a | 3817 |
| Tuba1c | 2963 |
| Chmp3 | -111 |
| Ist1 | -1821 |
| Chmp4c | -2092 |
| Spast | -3710 |
| Chmp2b | -8309 |
P75NTR REGULATES AXONOGENESIS
| set | P75NTR REGULATES AXONOGENESIS |
| setSize | 10 |
| pANOVA | 0.00685 |
| s.dist | -0.494 |
| p.adjustANOVA | 0.0659 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Mcf2 | -7953 |
| Rtn4 | -7633 |
| Omg | -7278 |
| Ngfr | -6659 |
| Rtn4r | -6173 |
| Ngf | -4926 |
| Mag | -4630 |
| Rhoa | -3098 |
| Lingo1 | -2615 |
| Arhgdia | 8150 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Mcf2 | -7953 |
| Rtn4 | -7633 |
| Omg | -7278 |
| Ngfr | -6659 |
| Rtn4r | -6173 |
| Ngf | -4926 |
| Mag | -4630 |
| Rhoa | -3098 |
| Lingo1 | -2615 |
| Arhgdia | 8150 |
APOPTOSIS INDUCED DNA FRAGMENTATION
| set | APOPTOSIS INDUCED DNA FRAGMENTATION |
| setSize | 10 |
| pANOVA | 0.00909 |
| s.dist | -0.476 |
| p.adjustANOVA | 0.0799 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| H1f2 | -8585 |
| H1f0 | -8564 |
| Hmgb1 | -7101 |
| Kpna1 | -6308 |
| Hmgb2 | -5788 |
| H1f4 | -2606 |
| Casp3 | -2348 |
| Kpnb1 | -1913 |
| Dffb | -1327 |
| Dffa | 3207 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H1f2 | -8585 |
| H1f0 | -8564 |
| Hmgb1 | -7101 |
| Kpna1 | -6308 |
| Hmgb2 | -5788 |
| H1f4 | -2606 |
| Casp3 | -2348 |
| Kpnb1 | -1913 |
| Dffb | -1327 |
| Dffa | 3207 |
WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2
| set | WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 |
| setSize | 13 |
| pANOVA | 0.00337 |
| s.dist | 0.47 |
| p.adjustANOVA | 0.0401 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Fzd2 | 7851 |
| Cltb | 7638 |
| Clta | 6913 |
| Ap2a1 | 6686 |
| Ap2s1 | 6398 |
| Fzd5 | 6237 |
| Ap2m1 | 6090 |
| Ap2a2 | 4320 |
| Ror1 | 2877 |
| Wnt5a | 2571 |
| Ror2 | 929 |
| Ap2b1 | -2191 |
| Cltc | -5100 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Fzd2 | 7851 |
| Cltb | 7638 |
| Clta | 6913 |
| Ap2a1 | 6686 |
| Ap2s1 | 6398 |
| Fzd5 | 6237 |
| Ap2m1 | 6090 |
| Ap2a2 | 4320 |
| Ror1 | 2877 |
| Wnt5a | 2571 |
| Ror2 | 929 |
| Ap2b1 | -2191 |
| Cltc | -5100 |
CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION
| set | CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION |
| setSize | 11 |
| pANOVA | 0.0108 |
| s.dist | -0.444 |
| p.adjustANOVA | 0.0912 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Ppp3r1 | -8475 |
| Ahcyl1 | -8415 |
| Ppp3ca | -8382 |
| Calm1 | -7913 |
| Ppp3cb | -7900 |
| Nfatc3 | -7647 |
| Itpr1 | -7383 |
| Nfatc1 | 247 |
| Itpr2 | 3162 |
| Itpr3 | 4751 |
| Nfatc2 | 5553 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Ppp3r1 | -8475 |
| Ahcyl1 | -8415 |
| Ppp3ca | -8382 |
| Calm1 | -7913 |
| Ppp3cb | -7900 |
| Nfatc3 | -7647 |
| Itpr1 | -7383 |
| Nfatc1 | 247 |
| Itpr2 | 3162 |
| Itpr3 | 4751 |
| Nfatc2 | 5553 |
GAP JUNCTION ASSEMBLY
| set | GAP JUNCTION ASSEMBLY |
| setSize | 21 |
| pANOVA | 0.000568 |
| s.dist | 0.434 |
| p.adjustANOVA | 0.0112 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Gja4 | 7674 |
| Tubb6 | 7443 |
| Tubb3 | 7249 |
| Tubb4a | 7218 |
| Tubb2b | 6485 |
| Gjb6 | 5880 |
| Gjd3 | 5295 |
| Tuba4a | 5173 |
| Tuba8 | 4756 |
| Tuba1c | 2963 |
| Gja5 | 2832 |
| Gjb1 | -810 |
| Gjc2 | -1110 |
| Gjd2 | -3854 |
| Gjc1 | -4130 |
| Gjb2 | -4214 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Gja4 | 7674 |
| Tubb6 | 7443 |
| Tubb3 | 7249 |
| Tubb4a | 7218 |
| Tubb2b | 6485 |
| Gjb6 | 5880 |
| Gjd3 | 5295 |
| Tuba4a | 5173 |
| Tuba8 | 4756 |
| Tuba1c | 2963 |
| Gja5 | 2832 |
| Gjb1 | -810 |
| Gjc2 | -1110 |
| Gjd2 | -3854 |
| Gjc1 | -4130 |
| Gjb2 | -4214 |
| Gja1 | -4297 |
IRE1ALPHA ACTIVATES CHAPERONES
| set | IRE1ALPHA ACTIVATES CHAPERONES |
| setSize | 50 |
| pANOVA | 4.02e-07 |
| s.dist | 0.414 |
| p.adjustANOVA | 7.89e-05 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Preb | 8329 |
| Pdia6 | 8314 |
| Lmna | 8036 |
| Cxxc1 | 7993 |
| Cul7 | 7974 |
| Tln1 | 7828 |
| Dnajb11 | 7757 |
| Hdgf | 7584 |
| Hspa5 | 7487 |
| Xbp1 | 7281 |
| Mydgf | 7186 |
| Klhdc3 | 7144 |
| Syvn1 | 7133 |
| Dctn1 | 7081 |
| Yif1a | 6754 |
| Srpr | 6547 |
| Acadvl | 6284 |
| Gosr2 | 6071 |
| Tspyl2 | 6056 |
| Hyou1 | 6018 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Preb | 8329 |
| Pdia6 | 8314 |
| Lmna | 8036 |
| Cxxc1 | 7993 |
| Cul7 | 7974 |
| Tln1 | 7828 |
| Dnajb11 | 7757 |
| Hdgf | 7584 |
| Hspa5 | 7487 |
| Xbp1 | 7281 |
| Mydgf | 7186 |
| Klhdc3 | 7144 |
| Syvn1 | 7133 |
| Dctn1 | 7081 |
| Yif1a | 6754 |
| Srpr | 6547 |
| Acadvl | 6284 |
| Gosr2 | 6071 |
| Tspyl2 | 6056 |
| Hyou1 | 6018 |
| Arfgap1 | 5801 |
| Srprb | 5762 |
| Pla2g4b | 5672 |
| Tpp1 | 5630 |
| Gsk3a | 5491 |
| Add1 | 5429 |
| Dnajc3 | 5337 |
| Ppp2r5b | 5277 |
| Sult1a1 | 4615 |
| Ddx11 | 4334 |
| Kdelr3 | 4255 |
| Fkbp14 | 4234 |
| Pdia5 | 3995 |
| Zbtb17 | 3514 |
| Shc1 | 2912 |
| Atp6v0d1 | 2718 |
| Extl3 | 2537 |
| Tatdn2 | 807 |
| Sec31a | -1310 |
| Ern1 | -1518 |
| Wipi1 | -2073 |
| Ctdsp2 | -2708 |
| Gfpt1 | -3691 |
| Serp1 | -4399 |
| Ssr1 | -4539 |
| Extl1 | -4808 |
| Wfs1 | -4914 |
| Edem1 | -5335 |
| Dnajb9 | -6988 |
| Extl2 | -7903 |
GLYCOGEN STORAGE DISEASES
| set | GLYCOGEN STORAGE DISEASES |
| setSize | 12 |
| pANOVA | 0.0142 |
| s.dist | 0.409 |
| p.adjustANOVA | 0.107 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Gaa | 7838 |
| Ubb | 7291 |
| G6pc3 | 6828 |
| Nhlrc1 | 5452 |
| Uba52 | 4628 |
| Gys1 | 4199 |
| Gbe1 | 4075 |
| Ppp1r3c | 3898 |
| Ubc | 2643 |
| Rps27a | 2562 |
| Gyg | -1666 |
| Epm2a | -6700 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Gaa | 7838 |
| Ubb | 7291 |
| G6pc3 | 6828 |
| Nhlrc1 | 5452 |
| Uba52 | 4628 |
| Gys1 | 4199 |
| Gbe1 | 4075 |
| Ppp1r3c | 3898 |
| Ubc | 2643 |
| Rps27a | 2562 |
| Gyg | -1666 |
| Epm2a | -6700 |
CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY
| set | CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY |
| setSize | 13 |
| pANOVA | 0.0111 |
| s.dist | 0.407 |
| p.adjustANOVA | 0.093 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Ciapin1 | 8111 |
| Nubp1 | 7783 |
| Ercc2 | 6866 |
| Ciao1 | 6819 |
| Pold1 | 5252 |
| Brip1 | 4585 |
| Ciao3 | 4564 |
| Nubp2 | 3987 |
| Mms19 | 3407 |
| Ciao2b | 2781 |
| Rtel1 | 239 |
| Ndor1 | -2783 |
| Abcb7 | -7378 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Ciapin1 | 8111 |
| Nubp1 | 7783 |
| Ercc2 | 6866 |
| Ciao1 | 6819 |
| Pold1 | 5252 |
| Brip1 | 4585 |
| Ciao3 | 4564 |
| Nubp2 | 3987 |
| Mms19 | 3407 |
| Ciao2b | 2781 |
| Rtel1 | 239 |
| Ndor1 | -2783 |
| Abcb7 | -7378 |
VOLTAGE GATED POTASSIUM CHANNELS
| set | VOLTAGE GATED POTASSIUM CHANNELS |
| setSize | 39 |
| pANOVA | 1.42e-05 |
| s.dist | -0.402 |
| p.adjustANOVA | 0.000798 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Kcna2 | -8534 |
| Kcnh7 | -8521 |
| Kcns1 | -8390 |
| Kcnab1 | -8331 |
| Kcnq5 | -7988 |
| Kcnv1 | -7976 |
| Kcnq3 | -7832 |
| Kcng1 | -7728 |
| Kcnab3 | -7682 |
| Kcnc2 | -7530 |
| Kcnd3 | -7438 |
| Kcnq1 | -7286 |
| Kcnd2 | -6984 |
| Kcnh3 | -6969 |
| Kcna1 | -6292 |
| Kcnb2 | -5930 |
| Kcnh5 | -5311 |
| Kcna4 | -5277 |
| Kcnf1 | -4998 |
| Kcns2 | -4940 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Kcna2 | -8534 |
| Kcnh7 | -8521 |
| Kcns1 | -8390 |
| Kcnab1 | -8331 |
| Kcnq5 | -7988 |
| Kcnv1 | -7976 |
| Kcnq3 | -7832 |
| Kcng1 | -7728 |
| Kcnab3 | -7682 |
| Kcnc2 | -7530 |
| Kcnd3 | -7438 |
| Kcnq1 | -7286 |
| Kcnd2 | -6984 |
| Kcnh3 | -6969 |
| Kcna1 | -6292 |
| Kcnb2 | -5930 |
| Kcnh5 | -5311 |
| Kcna4 | -5277 |
| Kcnf1 | -4998 |
| Kcns2 | -4940 |
| Kcnd1 | -4863 |
| Kcna6 | -3964 |
| Kcnb1 | -3810 |
| Kcnh1 | -2683 |
| Kcng4 | -2540 |
| Kcnc1 | -2106 |
| Kcnq2 | -2014 |
| Kcnh4 | -1514 |
| Kcna3 | -581 |
| Kcnab2 | -430 |
| Kcnh8 | 107 |
| Kcna5 | 809 |
| Kcnc3 | 1721 |
| Kcnq4 | 2730 |
| Kcnh2 | 3386 |
| Kcng2 | 3990 |
| Kcnc4 | 4382 |
| Kcnh6 | 5744 |
| Kcns3 | 7485 |
CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN
| set | CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN |
| setSize | 36 |
| pANOVA | 4.14e-05 |
| s.dist | 0.395 |
| p.adjustANOVA | 0.00181 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Ttll10 | 7533 |
| Tubb6 | 7443 |
| Ttll8 | 7378 |
| Tubb3 | 7249 |
| Tubb4a | 7218 |
| Ttll12 | 6621 |
| Tpgs1 | 6530 |
| Tubb2b | 6485 |
| Ttll11 | 6316 |
| Ttll9 | 6159 |
| Tuba4a | 5173 |
| Ttll1 | 4956 |
| Tuba8 | 4756 |
| Agbl5 | 4478 |
| Agbl2 | 4074 |
| Ttll6 | 3549 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Ttll10 | 7533 |
| Tubb6 | 7443 |
| Ttll8 | 7378 |
| Tubb3 | 7249 |
| Tubb4a | 7218 |
| Ttll12 | 6621 |
| Tpgs1 | 6530 |
| Tubb2b | 6485 |
| Ttll11 | 6316 |
| Ttll9 | 6159 |
| Tuba4a | 5173 |
| Ttll1 | 4956 |
| Tuba8 | 4756 |
| Agbl5 | 4478 |
| Agbl2 | 4074 |
| Ttll6 | 3549 |
| Svbp | 3379 |
| Ttll4 | 3174 |
| Ttl | 3169 |
| Tuba1c | 2963 |
| Nicn1 | 2665 |
| Agbl4 | 2633 |
| Ttll5 | 1137 |
| Lrrc49 | 494 |
| Ttll3 | 337 |
| Vash1 | -200 |
| Ttll13 | -1626 |
| Tpgs2 | -3179 |
| Agbl3 | -3649 |
| Vash2 | -4270 |
| Agtpbp1 | -7632 |
| Ttll7 | -8473 |
AGGREPHAGY
| set | AGGREPHAGY |
| setSize | 35 |
| pANOVA | 5.79e-05 |
| s.dist | 0.393 |
| p.adjustANOVA | 0.0022 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Hsf1 | 8293 |
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Vim | 7567 |
| Tubb6 | 7443 |
| Ubb | 7291 |
| Tubb3 | 7249 |
| Tubb4a | 7218 |
| Tubb2b | 6485 |
| Dync1i1 | 6412 |
| Vcp | 6085 |
| Ift88 | 5601 |
| Hdac6 | 5424 |
| Tuba4a | 5173 |
| Tuba8 | 4756 |
| Park7 | 4662 |
| Uba52 | 4628 |
| Dynll2 | 4072 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Hsf1 | 8293 |
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Vim | 7567 |
| Tubb6 | 7443 |
| Ubb | 7291 |
| Tubb3 | 7249 |
| Tubb4a | 7218 |
| Tubb2b | 6485 |
| Dync1i1 | 6412 |
| Vcp | 6085 |
| Ift88 | 5601 |
| Hdac6 | 5424 |
| Tuba4a | 5173 |
| Tuba8 | 4756 |
| Park7 | 4662 |
| Uba52 | 4628 |
| Dynll2 | 4072 |
| Ube2v1 | 3675 |
| Tuba1c | 2963 |
| Ubc | 2643 |
| Rps27a | 2562 |
| Dync1h1 | 2369 |
| Dync1li1 | 2257 |
| Dynll1 | 2074 |
| Prkn | -1437 |
| Cftr | -2285 |
| Pcnt | -3564 |
| Arl13b | -3571 |
| Dync1i2 | -4033 |
| Dync1li2 | -4384 |
| Ube2n | -7121 |
| Hsp90aa1 | -7566 |
THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT
| set | THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT |
| setSize | 66 |
| pANOVA | 5.42e-08 |
| s.dist | 0.387 |
| p.adjustANOVA | 2.13e-05 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Psmd7 | 8169 |
| Psmc4 | 8152 |
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Psmd3 | 8001 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Psmb5 | 7501 |
| Tubb6 | 7443 |
| Psme1 | 7422 |
| Psmd13 | 7345 |
| Ubb | 7291 |
| Tubb3 | 7249 |
| Tubb4a | 7218 |
| Psmb4 | 6979 |
| Sem1 | 6865 |
| Psmc3 | 6769 |
| Psmd4 | 6676 |
| Tubb2b | 6485 |
| Psmb6 | 6408 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Psmd7 | 8169 |
| Psmc4 | 8152 |
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Psmd3 | 8001 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Psmb5 | 7501 |
| Tubb6 | 7443 |
| Psme1 | 7422 |
| Psmd13 | 7345 |
| Ubb | 7291 |
| Tubb3 | 7249 |
| Tubb4a | 7218 |
| Psmb4 | 6979 |
| Sem1 | 6865 |
| Psmc3 | 6769 |
| Psmd4 | 6676 |
| Tubb2b | 6485 |
| Psmb6 | 6408 |
| Plk1 | 6346 |
| Psmb2 | 6259 |
| Psmc5 | 6152 |
| Psmd10 | 5869 |
| Psma5 | 5777 |
| Psme2 | 5538 |
| Psmd8 | 5385 |
| Tuba4a | 5173 |
| Psmb10 | 4885 |
| Psmc2 | 4876 |
| Tuba8 | 4756 |
| Uba52 | 4628 |
| Psmb7 | 4584 |
| Psmb1 | 4508 |
| Psmd2 | 4252 |
| Psma2 | 4189 |
| Ccnb2 | 4123 |
| Psma7 | 4049 |
| Psmb3 | 3609 |
| Psmd9 | 3389 |
| Tuba1c | 2963 |
| Ubc | 2643 |
| Rps27a | 2562 |
| Psma6 | 2339 |
| Psmd6 | 2281 |
| Cdkn1a | 2190 |
| Hsp90ab1 | 2022 |
| Psmd5 | 1755 |
| Psmd1 | 1243 |
| Trp53 | 1201 |
| Psmd14 | 139 |
| Psme3 | -87 |
| Psma4 | -131 |
| Psma1 | -846 |
| Psmf1 | -1103 |
| Psma3 | -1209 |
| Psmd11 | -2345 |
| Psmc1 | -2685 |
| Fkbpl | -3836 |
| Psmd12 | -4540 |
| Psmc6 | -5063 |
| Mapre1 | -5378 |
| Psme4 | -5595 |
| Psmb8 | -6859 |
| Psmb9 | -7447 |
| Hsp90aa1 | -7566 |
SODIUM CALCIUM EXCHANGERS
| set | SODIUM CALCIUM EXCHANGERS |
| setSize | 10 |
| pANOVA | 0.0353 |
| s.dist | -0.384 |
| p.adjustANOVA | 0.197 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Slc24a2 | -8535 |
| Slc8a1 | -8193 |
| Calm1 | -7913 |
| Sri | -6779 |
| Slc8b1 | -2409 |
| Slc24a3 | -2135 |
| Slc24a5 | -1807 |
| Slc24a4 | -1361 |
| Slc8a3 | 1469 |
| Slc8a2 | 4177 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Slc24a2 | -8535 |
| Slc8a1 | -8193 |
| Calm1 | -7913 |
| Sri | -6779 |
| Slc8b1 | -2409 |
| Slc24a3 | -2135 |
| Slc24a5 | -1807 |
| Slc24a4 | -1361 |
| Slc8a3 | 1469 |
| Slc8a2 | 4177 |
INTRAFLAGELLAR TRANSPORT
| set | INTRAFLAGELLAR TRANSPORT |
| setSize | 51 |
| pANOVA | 2.06e-06 |
| s.dist | 0.384 |
| p.adjustANOVA | 0.000243 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Dynlrb2 | 8377 |
| Ift122 | 8095 |
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Ift22 | 7913 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Dync2i2 | 7841 |
| Ift46 | 7683 |
| Ift172 | 7486 |
| Tubb6 | 7443 |
| Kif17 | 7328 |
| Tubb3 | 7249 |
| Tubb4a | 7218 |
| Ift74 | 7213 |
| Ift43 | 7004 |
| Tubb2b | 6485 |
| Dynlt5 | 5659 |
| Ift88 | 5601 |
| Ift57 | 5352 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Dynlrb2 | 8377 |
| Ift122 | 8095 |
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Ift22 | 7913 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Dync2i2 | 7841 |
| Ift46 | 7683 |
| Ift172 | 7486 |
| Tubb6 | 7443 |
| Kif17 | 7328 |
| Tubb3 | 7249 |
| Tubb4a | 7218 |
| Ift74 | 7213 |
| Ift43 | 7004 |
| Tubb2b | 6485 |
| Dynlt5 | 5659 |
| Ift88 | 5601 |
| Ift57 | 5352 |
| Tuba4a | 5173 |
| Ift140 | 4870 |
| Dync2i1 | 4818 |
| Ift52 | 4499 |
| Ift27 | 4201 |
| Dynll2 | 4072 |
| Wdr35 | 3963 |
| Tuba1c | 2963 |
| Dync2li1 | 2500 |
| Dynll1 | 2074 |
| Ttc30b | 1750 |
| Kif3c | 1730 |
| Dync2h1 | 1547 |
| Dynlrb1 | 1248 |
| Dynlt2a2 | 1142 |
| Hspb11 | 569 |
| Traf3ip1 | 437 |
| Cluap1 | 383 |
| Ift20 | 265 |
| Kif3a | 189 |
| Ttc30a1 | -328 |
| Kif3b | -349 |
| Ift80 | -814 |
| Ift81 | -1255 |
| Ttc21b | -1650 |
| Dynlt2b | -1873 |
| Trip11 | -2698 |
| Wdr19 | -3583 |
| Kifap3 | -5581 |
| Tnpo1 | -6038 |
| Ttc26 | -6599 |
COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING
| set | COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING |
| setSize | 26 |
| pANOVA | 0.000726 |
| s.dist | 0.383 |
| p.adjustANOVA | 0.0132 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Cct5 | 7963 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Tubb6 | 7443 |
| Cct7 | 7270 |
| Tubb3 | 7249 |
| Cct3 | 7238 |
| Tubb4a | 7218 |
| Tubb2b | 6485 |
| Tuba4a | 5173 |
| Tuba8 | 4756 |
| Pfdn1 | 4146 |
| Pfdn6 | 3895 |
| Cct4 | 3814 |
| Tuba1c | 2963 |
| Pfdn5 | 1707 |
| Pfdn2 | 870 |
| Cct2 | 622 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Cct5 | 7963 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Tubb6 | 7443 |
| Cct7 | 7270 |
| Tubb3 | 7249 |
| Cct3 | 7238 |
| Tubb4a | 7218 |
| Tubb2b | 6485 |
| Tuba4a | 5173 |
| Tuba8 | 4756 |
| Pfdn1 | 4146 |
| Pfdn6 | 3895 |
| Cct4 | 3814 |
| Tuba1c | 2963 |
| Pfdn5 | 1707 |
| Pfdn2 | 870 |
| Cct2 | 622 |
| Cct6a | -2054 |
| Cct8 | -2182 |
| Tcp1 | -3186 |
| Pfdn4 | -6243 |
| Vbp1 | -6481 |
| Actb | -7375 |
CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE
| set | CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE |
| setSize | 11 |
| pANOVA | 0.0281 |
| s.dist | -0.382 |
| p.adjustANOVA | 0.165 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Adcy1 | -8407 |
| Prkar2b | -7924 |
| Calm1 | -7913 |
| Prkx | -6774 |
| Adcy8 | -6525 |
| Creb1 | -4282 |
| Prkacb | -3510 |
| Prkar1a | -2085 |
| Prkar2a | -149 |
| Prkaca | 5428 |
| Prkar1b | 5498 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Adcy1 | -8407 |
| Prkar2b | -7924 |
| Calm1 | -7913 |
| Prkx | -6774 |
| Adcy8 | -6525 |
| Creb1 | -4282 |
| Prkacb | -3510 |
| Prkar1a | -2085 |
| Prkar2a | -149 |
| Prkaca | 5428 |
| Prkar1b | 5498 |
XENOBIOTICS
| set | XENOBIOTICS |
| setSize | 10 |
| pANOVA | 0.0377 |
| s.dist | -0.38 |
| p.adjustANOVA | 0.208 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Ahr | -8086 |
| Ahrr | -6676 |
| Cyp2j9 | -6033 |
| Cyp3a13 | -5419 |
| Cyp2d22 | -4563 |
| Cyp2a5 | -4552 |
| Arnt2 | -3122 |
| Cyp2s1 | -2150 |
| Arnt | 1265 |
| Cyp2f2 | 6271 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Ahr | -8086 |
| Ahrr | -6676 |
| Cyp2j9 | -6033 |
| Cyp3a13 | -5419 |
| Cyp2d22 | -4563 |
| Cyp2a5 | -4552 |
| Arnt2 | -3122 |
| Cyp2s1 | -2150 |
| Arnt | 1265 |
| Cyp2f2 | 6271 |
ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K
| set | ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K |
| setSize | 11 |
| pANOVA | 0.0296 |
| s.dist | -0.379 |
| p.adjustANOVA | 0.172 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Pik3ca | -7767 |
| Lyn | -6791 |
| Pik3r1 | -6578 |
| Gab1 | -6540 |
| Pik3cb | -6053 |
| Epor | -5014 |
| Pik3r5 | -3906 |
| Irs2 | -336 |
| Jak2 | 1450 |
| Pik3cd | 1891 |
| Pik3cg | 3339 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Pik3ca | -7767 |
| Lyn | -6791 |
| Pik3r1 | -6578 |
| Gab1 | -6540 |
| Pik3cb | -6053 |
| Epor | -5014 |
| Pik3r5 | -3906 |
| Irs2 | -336 |
| Jak2 | 1450 |
| Pik3cd | 1891 |
| Pik3cg | 3339 |
NEUROTOXICITY OF CLOSTRIDIUM TOXINS
| set | NEUROTOXICITY OF CLOSTRIDIUM TOXINS |
| setSize | 10 |
| pANOVA | 0.0385 |
| s.dist | -0.378 |
| p.adjustANOVA | 0.208 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Syt1 | -8595 |
| Snap25 | -8545 |
| Sv2b | -8126 |
| Syt2 | -7603 |
| Sv2c | -3799 |
| Vamp2 | -3527 |
| Vamp1 | -1069 |
| Stx1b | 405 |
| Sv2a | 634 |
| Stx1a | 7298 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Syt1 | -8595 |
| Snap25 | -8545 |
| Sv2b | -8126 |
| Syt2 | -7603 |
| Sv2c | -3799 |
| Vamp2 | -3527 |
| Vamp1 | -1069 |
| Stx1b | 405 |
| Sv2a | 634 |
| Stx1a | 7298 |
SIGNALING BY FGFR4 IN DISEASE
| set | SIGNALING BY FGFR4 IN DISEASE |
| setSize | 10 |
| pANOVA | 0.0394 |
| s.dist | -0.376 |
| p.adjustANOVA | 0.211 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Pik3ca | -7767 |
| Frs2 | -7124 |
| Kras | -6902 |
| Pik3r1 | -6578 |
| Nras | -6572 |
| Gab1 | -6540 |
| Sos1 | -4007 |
| Grb2 | 2786 |
| Plcg1 | 3728 |
| Hras | 6195 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Pik3ca | -7767 |
| Frs2 | -7124 |
| Kras | -6902 |
| Pik3r1 | -6578 |
| Nras | -6572 |
| Gab1 | -6540 |
| Sos1 | -4007 |
| Grb2 | 2786 |
| Plcg1 | 3728 |
| Hras | 6195 |
DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY
| set | DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY |
| setSize | 23 |
| pANOVA | 0.00196 |
| s.dist | -0.373 |
| p.adjustANOVA | 0.0285 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Ube2d1 | -8287 |
| Trim33 | -7842 |
| Smad3 | -7793 |
| Ncor1 | -7617 |
| Skil | -7606 |
| Nedd4l | -7591 |
| Ube2d3 | -6919 |
| Usp9x | -6023 |
| Smurf2 | -5450 |
| Rnf111 | -5385 |
| Parp1 | -5192 |
| Ski | -4986 |
| Tgif1 | -4547 |
| Tgif2 | -4236 |
| Smad2 | -2412 |
| Ppm1a | -2190 |
| Smad4 | -2153 |
| Hdac1 | -599 |
| Rps27a | 2562 |
| Ubc | 2643 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Ube2d1 | -8287 |
| Trim33 | -7842 |
| Smad3 | -7793 |
| Ncor1 | -7617 |
| Skil | -7606 |
| Nedd4l | -7591 |
| Ube2d3 | -6919 |
| Usp9x | -6023 |
| Smurf2 | -5450 |
| Rnf111 | -5385 |
| Parp1 | -5192 |
| Ski | -4986 |
| Tgif1 | -4547 |
| Tgif2 | -4236 |
| Smad2 | -2412 |
| Ppm1a | -2190 |
| Smad4 | -2153 |
| Hdac1 | -599 |
| Rps27a | 2562 |
| Ubc | 2643 |
| Uba52 | 4628 |
| Ncor2 | 4983 |
| Ubb | 7291 |
MET ACTIVATES RAP1 AND RAC1
| set | MET ACTIVATES RAP1 AND RAC1 |
| setSize | 10 |
| pANOVA | 0.0421 |
| s.dist | -0.371 |
| p.adjustANOVA | 0.221 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Rap1a | -7385 |
| Gab1 | -6540 |
| Rap1b | -6065 |
| Crkl | -5158 |
| Dock7 | -4616 |
| Met | -4272 |
| Rac1 | -3381 |
| Crk | -2189 |
| Grb2 | 2786 |
| Rapgef1 | 4474 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Rap1a | -7385 |
| Gab1 | -6540 |
| Rap1b | -6065 |
| Crkl | -5158 |
| Dock7 | -4616 |
| Met | -4272 |
| Rac1 | -3381 |
| Crk | -2189 |
| Grb2 | 2786 |
| Rapgef1 | 4474 |
RHO GTPASES ACTIVATE WASPS AND WAVES
| set | RHO GTPASES ACTIVATE WASPS AND WAVES |
| setSize | 36 |
| pANOVA | 0.000123 |
| s.dist | -0.37 |
| p.adjustANOVA | 0.0039 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Abi2 | -8465 |
| Actr2 | -8434 |
| Mapk1 | -8349 |
| Abi1 | -7872 |
| Actr3 | -7731 |
| Actb | -7375 |
| Wasf1 | -7306 |
| Wipf3 | -7253 |
| Btk | -7043 |
| Cdc42 | -6996 |
| Nckap1 | -6590 |
| Ptk2 | -6379 |
| Nckap1l | -5894 |
| Was | -5538 |
| Wipf2 | -5183 |
| Wasl | -5092 |
| Cyfip2 | -4770 |
| Brk1 | -3526 |
| Rac1 | -3381 |
| Wasf2 | -3291 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Abi2 | -8465 |
| Actr2 | -8434 |
| Mapk1 | -8349 |
| Abi1 | -7872 |
| Actr3 | -7731 |
| Actb | -7375 |
| Wasf1 | -7306 |
| Wipf3 | -7253 |
| Btk | -7043 |
| Cdc42 | -6996 |
| Nckap1 | -6590 |
| Ptk2 | -6379 |
| Nckap1l | -5894 |
| Was | -5538 |
| Wipf2 | -5183 |
| Wasl | -5092 |
| Cyfip2 | -4770 |
| Brk1 | -3526 |
| Rac1 | -3381 |
| Wasf2 | -3291 |
| Wipf1 | -3286 |
| Baiap2 | -3157 |
| Actg1 | -2768 |
| Nck1 | -2695 |
| Wasf3 | -2392 |
| Abl1 | -1988 |
| Cyfip1 | -1696 |
| Arpc2 | -1128 |
| Arpc5 | -894 |
| Arpc3 | 1528 |
| Arpc4 | 2187 |
| Grb2 | 2786 |
| Arpc1a | 4635 |
| Mapk3 | 4685 |
| Arpc1b | 6550 |
| Nckipsd | 8190 |
DEFECTIVE EXT2 CAUSES EXOSTOSES 2
| set | DEFECTIVE EXT2 CAUSES EXOSTOSES 2 |
| setSize | 14 |
| pANOVA | 0.0204 |
| s.dist | 0.358 |
| p.adjustANOVA | 0.134 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Sdc4 | 8044 |
| Gpc4 | 6965 |
| Gpc6 | 5972 |
| Sdc1 | 5862 |
| Ext2 | 4903 |
| Sdc3 | 4494 |
| Gpc2 | 4260 |
| Gpc3 | 3134 |
| Gpc1 | 2038 |
| Agrn | 2015 |
| Gpc5 | -16 |
| Ext1 | -1271 |
| Hspg2 | -1374 |
| Sdc2 | -3216 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Sdc4 | 8044 |
| Gpc4 | 6965 |
| Gpc6 | 5972 |
| Sdc1 | 5862 |
| Ext2 | 4903 |
| Sdc3 | 4494 |
| Gpc2 | 4260 |
| Gpc3 | 3134 |
| Gpc1 | 2038 |
| Agrn | 2015 |
| Gpc5 | -16 |
| Ext1 | -1271 |
| Hspg2 | -1374 |
| Sdc2 | -3216 |
HDR THROUGH MMEJ ALT NHEJ
| set | HDR THROUGH MMEJ ALT NHEJ |
| setSize | 10 |
| pANOVA | 0.0502 |
| s.dist | -0.358 |
| p.adjustANOVA | 0.234 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Rad50 | -8476 |
| Rbbp8 | -6171 |
| Nbn | -5734 |
| Parp1 | -5192 |
| Parp2 | -4004 |
| Polq | -3572 |
| Mre11a | -2951 |
| Lig3 | -2795 |
| Fen1 | 414 |
| Xrcc1 | 7289 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Rad50 | -8476 |
| Rbbp8 | -6171 |
| Nbn | -5734 |
| Parp1 | -5192 |
| Parp2 | -4004 |
| Polq | -3572 |
| Mre11a | -2951 |
| Lig3 | -2795 |
| Fen1 | 414 |
| Xrcc1 | 7289 |
PI3K EVENTS IN ERBB2 SIGNALING
| set | PI3K EVENTS IN ERBB2 SIGNALING |
| setSize | 15 |
| pANOVA | 0.0173 |
| s.dist | -0.355 |
| p.adjustANOVA | 0.117 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Nrg1 | -8488 |
| Nrg3 | -7906 |
| Pik3ca | -7767 |
| Erbb4 | -7702 |
| Egfr | -7104 |
| Pik3r1 | -6578 |
| Gab1 | -6540 |
| Erbb3 | -6356 |
| Egf | -5325 |
| Hbegf | -556 |
| Btc | -192 |
| Grb2 | 2786 |
| Nrg4 | 3773 |
| Erbb2 | 4214 |
| Nrg2 | 7310 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Nrg1 | -8488 |
| Nrg3 | -7906 |
| Pik3ca | -7767 |
| Erbb4 | -7702 |
| Egfr | -7104 |
| Pik3r1 | -6578 |
| Gab1 | -6540 |
| Erbb3 | -6356 |
| Egf | -5325 |
| Hbegf | -556 |
| Btc | -192 |
| Grb2 | 2786 |
| Nrg4 | 3773 |
| Erbb2 | 4214 |
| Nrg2 | 7310 |
COHESIN LOADING ONTO CHROMATIN
| set | COHESIN LOADING ONTO CHROMATIN |
| setSize | 10 |
| pANOVA | 0.0554 |
| s.dist | -0.35 |
| p.adjustANOVA | 0.25 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Stag1 | -7030 |
| Rad21 | -6531 |
| Stag2 | -6046 |
| Smc3 | -5233 |
| Wapl | -3901 |
| Pds5b | -3723 |
| Pds5a | -2927 |
| Nipbl | -1785 |
| Smc1a | 1103 |
| Mau2 | 5540 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Stag1 | -7030 |
| Rad21 | -6531 |
| Stag2 | -6046 |
| Smc3 | -5233 |
| Wapl | -3901 |
| Pds5b | -3723 |
| Pds5a | -2927 |
| Nipbl | -1785 |
| Smc1a | 1103 |
| Mau2 | 5540 |
CYTOSOLIC TRNA AMINOACYLATION
| set | CYTOSOLIC TRNA AMINOACYLATION |
| setSize | 24 |
| pANOVA | 0.00301 |
| s.dist | 0.35 |
| p.adjustANOVA | 0.0378 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Mars1 | 7865 |
| Vars | 6803 |
| Cars | 6710 |
| Farsa | 6315 |
| Yars | 6286 |
| Aimp2 | 6269 |
| Tars | 6075 |
| Qars | 5876 |
| Wars | 5829 |
| Ppa1 | 5204 |
| Farsb | 5157 |
| Eef1e1 | 5068 |
| Aimp1 | 4799 |
| Aars | 4586 |
| Hars | 4533 |
| Kars | 2992 |
| Gars | 2567 |
| Sars | 1059 |
| Rars | -12 |
| Nars | -1272 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Mars1 | 7865 |
| Vars | 6803 |
| Cars | 6710 |
| Farsa | 6315 |
| Yars | 6286 |
| Aimp2 | 6269 |
| Tars | 6075 |
| Qars | 5876 |
| Wars | 5829 |
| Ppa1 | 5204 |
| Farsb | 5157 |
| Eef1e1 | 5068 |
| Aimp1 | 4799 |
| Aars | 4586 |
| Hars | 4533 |
| Kars | 2992 |
| Gars | 2567 |
| Sars | 1059 |
| Rars | -12 |
| Nars | -1272 |
| Iars | -1525 |
| Dars | -6616 |
| Lars | -6752 |
| Eprs | -7849 |
REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA
| set | REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA |
| setSize | 13 |
| pANOVA | 0.0302 |
| s.dist | 0.347 |
| p.adjustANOVA | 0.174 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Ddx41 | 7495 |
| Ubb | 7291 |
| Irf3 | 6387 |
| Uba52 | 4628 |
| Trim56 | 4112 |
| Dtx4 | 3981 |
| Tbk1 | 2846 |
| Ubc | 2643 |
| Rps27a | 2562 |
| Trex1 | 1739 |
| Trim32 | 585 |
| Sting1 | -1332 |
| Trim21 | -5291 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Ddx41 | 7495 |
| Ubb | 7291 |
| Irf3 | 6387 |
| Uba52 | 4628 |
| Trim56 | 4112 |
| Dtx4 | 3981 |
| Tbk1 | 2846 |
| Ubc | 2643 |
| Rps27a | 2562 |
| Trex1 | 1739 |
| Trim32 | 585 |
| Sting1 | -1332 |
| Trim21 | -5291 |
MATURATION OF NUCLEOPROTEIN
| set | MATURATION OF NUCLEOPROTEIN |
| setSize | 10 |
| pANOVA | 0.0585 |
| s.dist | -0.346 |
| p.adjustANOVA | 0.262 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Parp14 | -8525 |
| Gsk3b | -7578 |
| Parp6 | -4693 |
| Sumo1 | -4065 |
| Parp4 | -3935 |
| Parp9 | -3072 |
| Parp16 | -1441 |
| Ube2i | -1107 |
| Parp8 | 14 |
| Parp10 | 4242 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Parp14 | -8525 |
| Gsk3b | -7578 |
| Parp6 | -4693 |
| Sumo1 | -4065 |
| Parp4 | -3935 |
| Parp9 | -3072 |
| Parp16 | -1441 |
| Ube2i | -1107 |
| Parp8 | 14 |
| Parp10 | 4242 |
REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX
| set | REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX |
| setSize | 15 |
| pANOVA | 0.0216 |
| s.dist | -0.343 |
| p.adjustANOVA | 0.138 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Dld | -7300 |
| Pdk3 | -6982 |
| Pdk4 | -6758 |
| Pdha1 | -6204 |
| Pdpr | -6087 |
| Pdp2 | -5240 |
| Pdhx | -4886 |
| Dlat | -4828 |
| Pdp1 | -4718 |
| Pdk1 | -1948 |
| Pdk2 | -1881 |
| Pdhb | -1161 |
| Gstz1 | 1774 |
| Ppard | 4964 |
| Rxra | 6407 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Dld | -7300 |
| Pdk3 | -6982 |
| Pdk4 | -6758 |
| Pdha1 | -6204 |
| Pdpr | -6087 |
| Pdp2 | -5240 |
| Pdhx | -4886 |
| Dlat | -4828 |
| Pdp1 | -4718 |
| Pdk1 | -1948 |
| Pdk2 | -1881 |
| Pdhb | -1161 |
| Gstz1 | 1774 |
| Ppard | 4964 |
| Rxra | 6407 |
ACTIVATION OF AMPK DOWNSTREAM OF NMDARS
| set | ACTIVATION OF AMPK DOWNSTREAM OF NMDARS |
| setSize | 20 |
| pANOVA | 0.00881 |
| s.dist | 0.338 |
| p.adjustANOVA | 0.0786 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Tubb6 | 7443 |
| Tubb3 | 7249 |
| Tubb4a | 7218 |
| Tubb2b | 6485 |
| Mapt | 5513 |
| Tuba4a | 5173 |
| Prkag1 | 4834 |
| Tuba8 | 4756 |
| Tuba1c | 2963 |
| Prkab1 | 1687 |
| Prkag2 | 150 |
| Camkk2 | -3991 |
| Prkab2 | -4190 |
| Prkaa1 | -5558 |
| Prkaa2 | -7288 |
| Calm1 | -7913 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Tubb4b | 8034 |
| Tubb2a | 8027 |
| Tuba1a | 7897 |
| Tuba1b | 7879 |
| Tubb6 | 7443 |
| Tubb3 | 7249 |
| Tubb4a | 7218 |
| Tubb2b | 6485 |
| Mapt | 5513 |
| Tuba4a | 5173 |
| Prkag1 | 4834 |
| Tuba8 | 4756 |
| Tuba1c | 2963 |
| Prkab1 | 1687 |
| Prkag2 | 150 |
| Camkk2 | -3991 |
| Prkab2 | -4190 |
| Prkaa1 | -5558 |
| Prkaa2 | -7288 |
| Calm1 | -7913 |
CAMK IV MEDIATED PHOSPHORYLATION OF CREB
| set | CAMK IV MEDIATED PHOSPHORYLATION OF CREB |
| setSize | 10 |
| pANOVA | 0.0644 |
| s.dist | -0.338 |
| p.adjustANOVA | 0.278 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Calm1 | -7913 |
| Camk2a | -7607 |
| Camk2d | -7204 |
| Camk4 | -5900 |
| Creb1 | -4282 |
| Camkk2 | -3991 |
| Kpna2 | -651 |
| Camk2b | 1443 |
| Camkk1 | 1725 |
| Camk2g | 4878 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Calm1 | -7913 |
| Camk2a | -7607 |
| Camk2d | -7204 |
| Camk4 | -5900 |
| Creb1 | -4282 |
| Camkk2 | -3991 |
| Kpna2 | -651 |
| Camk2b | 1443 |
| Camkk1 | 1725 |
| Camk2g | 4878 |
DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS
| set | DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS |
| setSize | 18 |
| pANOVA | 0.0141 |
| s.dist | 0.334 |
| p.adjustANOVA | 0.107 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Pgm1 | 8304 |
| Neu1 | 8207 |
| Galk1 | 8079 |
| Dpm3 | 7165 |
| Gale | 6210 |
| Dhdds | 5101 |
| Mpi | 4447 |
| Dolk | 3473 |
| Srd5a3 | 2962 |
| Glb1 | 2460 |
| Gne | 2102 |
| Ctsa | 2035 |
| Galt | 771 |
| Dpm2 | -80 |
| Pmm2 | -482 |
| Nus1 | -3132 |
| Gfpt1 | -3691 |
| Dpm1 | -3816 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Pgm1 | 8304 |
| Neu1 | 8207 |
| Galk1 | 8079 |
| Dpm3 | 7165 |
| Gale | 6210 |
| Dhdds | 5101 |
| Mpi | 4447 |
| Dolk | 3473 |
| Srd5a3 | 2962 |
| Glb1 | 2460 |
| Gne | 2102 |
| Ctsa | 2035 |
| Galt | 771 |
| Dpm2 | -80 |
| Pmm2 | -482 |
| Nus1 | -3132 |
| Gfpt1 | -3691 |
| Dpm1 | -3816 |
INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE
| set | INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE |
| setSize | 22 |
| pANOVA | 0.00693 |
| s.dist | 0.333 |
| p.adjustANOVA | 0.0659 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Sgta | 7678 |
| Get3 | 7456 |
| Stx1a | 7298 |
| Get1 | 7198 |
| Stx5a | 6889 |
| Get4 | 6825 |
| Emd | 6126 |
| Bag6 | 5819 |
| Sec61g | 5347 |
| Sec61b | 5241 |
| Hmox1 | 3879 |
| App | 2249 |
| Ubl4a | 1737 |
| Cyb5a | 415 |
| Ube2j2 | 106 |
| Prnp | -110 |
| Otof | -339 |
| Caml | -880 |
| Aldh3a2 | -1619 |
| Vapa | -2475 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Sgta | 7678 |
| Get3 | 7456 |
| Stx1a | 7298 |
| Get1 | 7198 |
| Stx5a | 6889 |
| Get4 | 6825 |
| Emd | 6126 |
| Bag6 | 5819 |
| Sec61g | 5347 |
| Sec61b | 5241 |
| Hmox1 | 3879 |
| App | 2249 |
| Ubl4a | 1737 |
| Cyb5a | 415 |
| Ube2j2 | 106 |
| Prnp | -110 |
| Otof | -339 |
| Caml | -880 |
| Aldh3a2 | -1619 |
| Vapa | -2475 |
| Vamp2 | -3527 |
| Serp1 | -4399 |
DISEASES OF CARBOHYDRATE METABOLISM
| set | DISEASES OF CARBOHYDRATE METABOLISM |
| setSize | 28 |
| pANOVA | 0.00247 |
| s.dist | 0.33 |
| p.adjustANOVA | 0.0321 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Sgsh | 8093 |
| Gaa | 7838 |
| Taldo1 | 7523 |
| Ubb | 7291 |
| G6pc3 | 6828 |
| Khk | 6701 |
| Nhlrc1 | 5452 |
| Galns | 5081 |
| Uba52 | 4628 |
| Hyal1 | 4500 |
| Gys1 | 4199 |
| Gbe1 | 4075 |
| Gusb | 4023 |
| Ppp1r3c | 3898 |
| Rpia | 3046 |
| Ubc | 2643 |
| Rps27a | 2562 |
| Glb1 | 2460 |
| Gns | 2365 |
| Aldob | 1990 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Sgsh | 8093 |
| Gaa | 7838 |
| Taldo1 | 7523 |
| Ubb | 7291 |
| G6pc3 | 6828 |
| Khk | 6701 |
| Nhlrc1 | 5452 |
| Galns | 5081 |
| Uba52 | 4628 |
| Hyal1 | 4500 |
| Gys1 | 4199 |
| Gbe1 | 4075 |
| Gusb | 4023 |
| Ppp1r3c | 3898 |
| Rpia | 3046 |
| Ubc | 2643 |
| Rps27a | 2562 |
| Glb1 | 2460 |
| Gns | 2365 |
| Aldob | 1990 |
| Dcxr | 670 |
| Idua | 607 |
| Naglu | -1235 |
| Hgsnat | -1382 |
| Arsb | -1428 |
| Gyg | -1666 |
| Epm2a | -6700 |
| Ids | -7070 |
KERATAN SULFATE DEGRADATION
| set | KERATAN SULFATE DEGRADATION |
| setSize | 12 |
| pANOVA | 0.0517 |
| s.dist | 0.324 |
| p.adjustANOVA | 0.238 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Hexa | 7239 |
| Prelp | 6607 |
| Fmod | 6014 |
| Lum | 5928 |
| Galns | 5081 |
| Glb1l | 3635 |
| Omd | 2873 |
| Glb1 | 2460 |
| Gns | 2365 |
| Ogn | -441 |
| Acan | -3736 |
| Hexb | -5625 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Hexa | 7239 |
| Prelp | 6607 |
| Fmod | 6014 |
| Lum | 5928 |
| Galns | 5081 |
| Glb1l | 3635 |
| Omd | 2873 |
| Glb1 | 2460 |
| Gns | 2365 |
| Ogn | -441 |
| Acan | -3736 |
| Hexb | -5625 |
AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA
| set | AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA |
| setSize | 53 |
| pANOVA | 4.71e-05 |
| s.dist | 0.323 |
| p.adjustANOVA | 0.00198 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Psmd7 | 8169 |
| Psmc4 | 8152 |
| Psmd3 | 8001 |
| Hspb1 | 7813 |
| Psmb5 | 7501 |
| Psme1 | 7422 |
| Psmd13 | 7345 |
| Ubb | 7291 |
| Psmb4 | 6979 |
| Sem1 | 6865 |
| Psmc3 | 6769 |
| Psmd4 | 6676 |
| Psmb6 | 6408 |
| Psmb2 | 6259 |
| Psmc5 | 6152 |
| Psmd10 | 5869 |
| Psma5 | 5777 |
| Psme2 | 5538 |
| Psmd8 | 5385 |
| Eif4g1 | 5091 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Psmd7 | 8169 |
| Psmc4 | 8152 |
| Psmd3 | 8001 |
| Hspb1 | 7813 |
| Psmb5 | 7501 |
| Psme1 | 7422 |
| Psmd13 | 7345 |
| Ubb | 7291 |
| Psmb4 | 6979 |
| Sem1 | 6865 |
| Psmc3 | 6769 |
| Psmd4 | 6676 |
| Psmb6 | 6408 |
| Psmb2 | 6259 |
| Psmc5 | 6152 |
| Psmd10 | 5869 |
| Psma5 | 5777 |
| Psme2 | 5538 |
| Psmd8 | 5385 |
| Eif4g1 | 5091 |
| Psmb10 | 4885 |
| Psmc2 | 4876 |
| Uba52 | 4628 |
| Psmb7 | 4584 |
| Psmb1 | 4508 |
| Psmd2 | 4252 |
| Psma2 | 4189 |
| Psma7 | 4049 |
| Hspa8 | 3754 |
| Psmb3 | 3609 |
| Psmd9 | 3389 |
| Ubc | 2643 |
| Rps27a | 2562 |
| Psma6 | 2339 |
| Psmd6 | 2281 |
| Psmd5 | 1755 |
| Psmd1 | 1243 |
| Psmd14 | 139 |
| Psme3 | -87 |
| Psma4 | -131 |
| Hspa1a | -835 |
| Psma1 | -846 |
| Psmf1 | -1103 |
| Psma3 | -1209 |
| Psmd11 | -2345 |
| Psmc1 | -2685 |
| Psmd12 | -4540 |
| Psmc6 | -5063 |
| Psme4 | -5595 |
| Psmb8 | -6859 |
| Pabpc1 | -6891 |
| Hnrnpd | -7272 |
| Psmb9 | -7447 |
CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES
| set | CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES |
| setSize | 46 |
| pANOVA | 0.00016 |
| s.dist | 0.322 |
| p.adjustANOVA | 0.00461 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Psmd7 | 8169 |
| Psmc4 | 8152 |
| Psmd3 | 8001 |
| Psmb5 | 7501 |
| Psme1 | 7422 |
| Psmd13 | 7345 |
| Mrc2 | 7063 |
| Psmb4 | 6979 |
| Sem1 | 6865 |
| Psmc3 | 6769 |
| Psmd4 | 6676 |
| Psmb6 | 6408 |
| Psmb2 | 6259 |
| Psmc5 | 6152 |
| Psmd10 | 5869 |
| Psma5 | 5777 |
| Psme2 | 5538 |
| Psmd8 | 5385 |
| Psmb10 | 4885 |
| Psmc2 | 4876 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Psmd7 | 8169 |
| Psmc4 | 8152 |
| Psmd3 | 8001 |
| Psmb5 | 7501 |
| Psme1 | 7422 |
| Psmd13 | 7345 |
| Mrc2 | 7063 |
| Psmb4 | 6979 |
| Sem1 | 6865 |
| Psmc3 | 6769 |
| Psmd4 | 6676 |
| Psmb6 | 6408 |
| Psmb2 | 6259 |
| Psmc5 | 6152 |
| Psmd10 | 5869 |
| Psma5 | 5777 |
| Psme2 | 5538 |
| Psmd8 | 5385 |
| Psmb10 | 4885 |
| Psmc2 | 4876 |
| Psmb7 | 4584 |
| Psmb1 | 4508 |
| Psmd2 | 4252 |
| Psma2 | 4189 |
| Psma7 | 4049 |
| Psmb3 | 3609 |
| Psmd9 | 3389 |
| Psma6 | 2339 |
| Psmd6 | 2281 |
| Psmd5 | 1755 |
| Psmd1 | 1243 |
| Psmd14 | 139 |
| Psme3 | -87 |
| Psma4 | -131 |
| Psma1 | -846 |
| Psmf1 | -1103 |
| Psma3 | -1209 |
| Psmd11 | -2345 |
| Psmc1 | -2685 |
| Mrc1 | -3331 |
| Fcgr1 | -4229 |
| Psmd12 | -4540 |
| Psmc6 | -5063 |
| Psme4 | -5595 |
| Psmb8 | -6859 |
| Psmb9 | -7447 |
KERATAN SULFATE BIOSYNTHESIS
| set | KERATAN SULFATE BIOSYNTHESIS |
| setSize | 24 |
| pANOVA | 0.00639 |
| s.dist | 0.322 |
| p.adjustANOVA | 0.0638 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| B4galt2 | 8171 |
| St3gal4 | 8159 |
| B4galt4 | 7662 |
| B4galt3 | 7116 |
| St3gal2 | 6982 |
| Prelp | 6607 |
| Chst1 | 6358 |
| Chst5 | 6328 |
| Fmod | 6014 |
| Lum | 5928 |
| St3gal3 | 3821 |
| B3gnt4 | 3755 |
| B4gat1 | 3397 |
| B4galt5 | 2890 |
| Omd | 2873 |
| Chst2 | 1889 |
| B3gnt7 | 262 |
| B3gnt2 | -422 |
| Ogn | -441 |
| St3gal1 | -1814 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| B4galt2 | 8171 |
| St3gal4 | 8159 |
| B4galt4 | 7662 |
| B4galt3 | 7116 |
| St3gal2 | 6982 |
| Prelp | 6607 |
| Chst1 | 6358 |
| Chst5 | 6328 |
| Fmod | 6014 |
| Lum | 5928 |
| St3gal3 | 3821 |
| B3gnt4 | 3755 |
| B4gat1 | 3397 |
| B4galt5 | 2890 |
| Omd | 2873 |
| Chst2 | 1889 |
| B3gnt7 | 262 |
| B3gnt2 | -422 |
| Ogn | -441 |
| St3gal1 | -1814 |
| B4galt6 | -3698 |
| Acan | -3736 |
| B4galt1 | -6119 |
| St3gal6 | -7783 |
SIGNALING BY FGFR3 FUSIONS IN CANCER
| set | SIGNALING BY FGFR3 FUSIONS IN CANCER |
| setSize | 10 |
| pANOVA | 0.0792 |
| s.dist | -0.321 |
| p.adjustANOVA | 0.314 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Pik3ca | -7767 |
| Frs2 | -7124 |
| Kras | -6902 |
| Pik3r1 | -6578 |
| Nras | -6572 |
| Gab1 | -6540 |
| Sos1 | -4007 |
| Grb2 | 2786 |
| Hras | 6195 |
| Fgfr3 | 8471 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Pik3ca | -7767 |
| Frs2 | -7124 |
| Kras | -6902 |
| Pik3r1 | -6578 |
| Nras | -6572 |
| Gab1 | -6540 |
| Sos1 | -4007 |
| Grb2 | 2786 |
| Hras | 6195 |
| Fgfr3 | 8471 |
REGULATION OF RUNX3 EXPRESSION AND ACTIVITY
| set | REGULATION OF RUNX3 EXPRESSION AND ACTIVITY |
| setSize | 53 |
| pANOVA | 5.75e-05 |
| s.dist | 0.319 |
| p.adjustANOVA | 0.0022 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Psmd7 | 8169 |
| Psmc4 | 8152 |
| Psmd3 | 8001 |
| Psmb5 | 7501 |
| Psme1 | 7422 |
| Psmd13 | 7345 |
| Ubb | 7291 |
| Psmb4 | 6979 |
| Sem1 | 6865 |
| Psmc3 | 6769 |
| Psmd4 | 6676 |
| Psmb6 | 6408 |
| Psmb2 | 6259 |
| Psmc5 | 6152 |
| Psmd10 | 5869 |
| Psma5 | 5777 |
| Psme2 | 5538 |
| Psmd8 | 5385 |
| Psmb10 | 4885 |
| Psmc2 | 4876 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Psmd7 | 8169 |
| Psmc4 | 8152 |
| Psmd3 | 8001 |
| Psmb5 | 7501 |
| Psme1 | 7422 |
| Psmd13 | 7345 |
| Ubb | 7291 |
| Psmb4 | 6979 |
| Sem1 | 6865 |
| Psmc3 | 6769 |
| Psmd4 | 6676 |
| Psmb6 | 6408 |
| Psmb2 | 6259 |
| Psmc5 | 6152 |
| Psmd10 | 5869 |
| Psma5 | 5777 |
| Psme2 | 5538 |
| Psmd8 | 5385 |
| Psmb10 | 4885 |
| Psmc2 | 4876 |
| Uba52 | 4628 |
| Psmb7 | 4584 |
| Psmb1 | 4508 |
| Psmd2 | 4252 |
| Psma2 | 4189 |
| Src | 4103 |
| Psma7 | 4049 |
| Psmb3 | 3609 |
| Psmd9 | 3389 |
| Tgfb1 | 2828 |
| Ubc | 2643 |
| Rps27a | 2562 |
| Psma6 | 2339 |
| Psmd6 | 2281 |
| Psmd5 | 1755 |
| Psmd1 | 1243 |
| Psmd14 | 139 |
| Mdm2 | 121 |
| Psme3 | -87 |
| Psma4 | -131 |
| Psma1 | -846 |
| Psmf1 | -1103 |
| Psma3 | -1209 |
| Smurf1 | -1563 |
| Ep300 | -2009 |
| Psmd11 | -2345 |
| Psmc1 | -2685 |
| Cbfb | -3647 |
| Psmd12 | -4540 |
| Psmc6 | -5063 |
| Smurf2 | -5450 |
| Psmb8 | -6859 |
| Psmb9 | -7447 |
RA BIOSYNTHESIS PATHWAY
| set | RA BIOSYNTHESIS PATHWAY |
| setSize | 12 |
| pANOVA | 0.0554 |
| s.dist | 0.319 |
| p.adjustANOVA | 0.25 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Aldh1a1 | 8243 |
| Crabp1 | 7111 |
| Rdh5 | 7035 |
| Dhrs4 | 6318 |
| Rdh14 | 2717 |
| Rdh11 | 2139 |
| Rdh10 | 1554 |
| Aldh1a3 | 1357 |
| Rdh13 | 1085 |
| Dhrs3 | 974 |
| Aldh1a2 | -1668 |
| Cyp26b1 | -4970 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Aldh1a1 | 8243 |
| Crabp1 | 7111 |
| Rdh5 | 7035 |
| Dhrs4 | 6318 |
| Rdh14 | 2717 |
| Rdh11 | 2139 |
| Rdh10 | 1554 |
| Aldh1a3 | 1357 |
| Rdh13 | 1085 |
| Dhrs3 | 974 |
| Aldh1a2 | -1668 |
| Cyp26b1 | -4970 |
Here is the session info with all the versions of packages used.
sessionInfo()## R version 4.4.0 (2024-04-24)
## Platform: x86_64-pc-linux-gnu
## Running under: Ubuntu 22.04.4 LTS
##
## Matrix products: default
## BLAS: /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.10.0
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.10.0
##
## locale:
## [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
## [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8
## [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
## [7] LC_PAPER=en_US.UTF-8 LC_NAME=C
## [9] LC_ADDRESS=C LC_TELEPHONE=C
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
##
## time zone: Australia/Melbourne
## tzcode source: system (glibc)
##
## attached base packages:
## [1] stats4 stats graphics grDevices utils datasets methods
## [8] base
##
## other attached packages:
## [1] GGally_2.2.1 ggplot2_3.5.1
## [3] gtools_3.9.5 tibble_3.2.1
## [5] dplyr_1.1.4 echarts4r_0.4.5
## [7] beeswarm_0.4.0 pkgload_1.3.4
## [9] vioplot_0.4.0 sm_2.2-6.0
## [11] kableExtra_1.4.0 topconfects_1.20.0
## [13] limma_3.60.0 eulerr_7.0.2
## [15] mitch_1.16.0 MASS_7.3-60.2
## [17] fgsea_1.30.0 gplots_3.1.3.1
## [19] DESeq2_1.44.0 SummarizedExperiment_1.34.0
## [21] Biobase_2.64.0 MatrixGenerics_1.16.0
## [23] matrixStats_1.3.0 GenomicRanges_1.56.0
## [25] GenomeInfoDb_1.40.0 IRanges_2.38.0
## [27] S4Vectors_0.42.0 BiocGenerics_0.50.0
## [29] reshape2_1.4.4 zoo_1.8-12
##
## loaded via a namespace (and not attached):
## [1] bitops_1.0-7 gridExtra_2.3 rlang_1.1.4
## [4] magrittr_2.0.3 compiler_4.4.0 polylabelr_0.2.0
## [7] systemfonts_1.1.0 vctrs_0.6.5 stringr_1.5.1
## [10] pkgconfig_2.0.3 crayon_1.5.2 fastmap_1.2.0
## [13] XVector_0.44.0 caTools_1.18.2 utf8_1.2.4
## [16] promises_1.3.0 rmarkdown_2.27 UCSC.utils_1.0.0
## [19] purrr_1.0.2 xfun_0.44 zlibbioc_1.50.0
## [22] cachem_1.1.0 jsonlite_1.8.8 highr_0.11
## [25] later_1.3.2 DelayedArray_0.30.1 BiocParallel_1.38.0
## [28] parallel_4.4.0 R6_2.5.1 bslib_0.7.0
## [31] stringi_1.8.4 RColorBrewer_1.1-3 jquerylib_0.1.4
## [34] Rcpp_1.0.12 assertthat_0.2.1 knitr_1.47
## [37] httpuv_1.6.15 Matrix_1.7-0 tidyselect_1.2.1
## [40] rstudioapi_0.16.0 abind_1.4-5 yaml_2.3.8
## [43] codetools_0.2-20 lattice_0.22-6 plyr_1.8.9
## [46] withr_3.0.0 shiny_1.8.1.1 evaluate_0.23
## [49] polyclip_1.10-6 ggstats_0.6.0 xml2_1.3.6
## [52] pillar_1.9.0 KernSmooth_2.23-24 generics_0.1.3
## [55] munsell_0.5.1 scales_1.3.0 xtable_1.8-4
## [58] glue_1.7.0 tools_4.4.0 data.table_1.15.4
## [61] locfit_1.5-9.9 fastmatch_1.1-4 cowplot_1.1.3
## [64] grid_4.4.0 tidyr_1.3.1 colorspace_2.1-0
## [67] GenomeInfoDbData_1.2.12 cli_3.6.2 fansi_1.0.6
## [70] S4Arrays_1.4.0 viridisLite_0.4.2 svglite_2.1.3
## [73] gtable_0.3.5 sass_0.4.9 digest_0.6.35
## [76] SparseArray_1.4.3 htmlwidgets_1.6.4 htmltools_0.5.8.1
## [79] lifecycle_1.0.4 httr_1.4.7 statmod_1.5.0
## [82] mime_0.12END of report