Mitch Report
Antony Kaspi & Mark Ziemann
date generated: 2024-06-05
Background
Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch
Input profiles
Here is the first few lines of the input profile.
| x | |
|---|---|
| 0610009B22Rik | 0.0972207 |
| 0610009E02Rik | 1.2632625 |
| 0610009L18Rik | -0.6637497 |
| 0610010K14Rik | -0.4536898 |
| 0610012G03Rik | 0.1223624 |
| 0610030E20Rik | -0.0456229 |
Here are some metrics about the input data profile:
| Profile metrics | |
|---|---|
| num_genesets | 1604 |
| num_genes_in_profile | 17098 |
| duplicated_genes_present | 0 |
| num_profile_genes_in_sets | 8378 |
| num_profile_genes_not_in_sets | 8720 |
Here is a plot of the input profiles. Note the dynamic ranges.
Here is the contour plot of the profile including all detected genes.
Input genesets
Here are some metrics about the gene sets used:
GMT file of genesets:| Gene sets metrics | |
|---|---|
| num_genesets | 1604 |
| num_genesets_excluded | 426 |
| num_genesets_included | 1178 |
Differential pathway expression
Interactive enrichment scatterplot
Significance is calculated by -log10(p-value). All points shown are FDR<0.05.
Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.
Results table
Top N= 50 gene sets| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| EUKARYOTIC TRANSLATION ELONGATION | 87 | 5.04e-34 | 0.753 | 5.94e-31 |
| SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | 106 | 4.10e-33 | 0.673 | 2.41e-30 |
| RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY | 95 | 7.03e-28 | 0.649 | 1.66e-25 |
| EUKARYOTIC TRANSLATION INITIATION | 114 | 5.60e-31 | 0.627 | 1.65e-28 |
| REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO | 10 | 6.04e-04 | -0.626 | 6.66e-03 |
| YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | 11 | 4.32e-04 | 0.613 | 5.04e-03 |
| ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | 59 | 9.20e-15 | 0.583 | 7.74e-13 |
| SELENOAMINO ACID METABOLISM | 109 | 2.15e-25 | 0.577 | 4.22e-23 |
| ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS | 10 | 2.45e-03 | -0.553 | 2.09e-02 |
| FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | 18 | 7.61e-05 | 0.539 | 1.34e-03 |
| NONSENSE MEDIATED DECAY NMD | 109 | 2.99e-21 | 0.524 | 3.91e-19 |
| COMPLEX I BIOGENESIS | 56 | 1.96e-11 | 0.518 | 1.21e-09 |
| CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | 12 | 1.97e-03 | -0.516 | 1.75e-02 |
| SEROTONIN NEUROTRANSMITTER RELEASE CYCLE | 18 | 1.95e-04 | -0.507 | 2.82e-03 |
| ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS | 10 | 6.11e-03 | -0.501 | 4.50e-02 |
| HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | 10 | 6.11e-03 | -0.501 | 4.50e-02 |
| ENDOSOMAL VACUOLAR PATHWAY | 11 | 4.83e-03 | 0.491 | 3.77e-02 |
| SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX | 13 | 3.16e-03 | 0.473 | 2.65e-02 |
| REGULATION OF EXPRESSION OF SLITS AND ROBOS | 160 | 9.48e-25 | 0.470 | 1.40e-22 |
| RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | 125 | 5.98e-19 | 0.460 | 7.05e-17 |
| RESPIRATORY ELECTRON TRANSPORT | 102 | 1.43e-15 | 0.457 | 1.41e-13 |
| NEUROTOXICITY OF CLOSTRIDIUM TOXINS | 10 | 1.33e-02 | -0.452 | 8.41e-02 |
| HDR THROUGH MMEJ ALT NHEJ | 10 | 1.36e-02 | -0.451 | 8.50e-02 |
| CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND | 10 | 1.45e-02 | -0.446 | 8.80e-02 |
| GLUTATHIONE CONJUGATION | 29 | 5.58e-05 | 0.432 | 1.11e-03 |
| SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | 12 | 9.99e-03 | 0.430 | 6.76e-02 |
| PHASE 4 RESTING MEMBRANE POTENTIAL | 14 | 6.04e-03 | -0.424 | 4.50e-02 |
| DSCAM INTERACTIONS | 10 | 2.07e-02 | -0.423 | 1.13e-01 |
| RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA | 24 | 3.77e-04 | -0.419 | 4.54e-03 |
| CELLULAR RESPONSE TO STARVATION | 146 | 4.58e-18 | 0.415 | 4.90e-16 |
| CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | 46 | 1.19e-06 | 0.414 | 4.39e-05 |
| MITOCHONDRIAL FATTY ACID BETA OXIDATION | 34 | 2.97e-05 | 0.414 | 6.72e-04 |
| TRANSLATION | 286 | 7.32e-33 | 0.410 | 2.87e-30 |
| REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | 29 | 1.33e-04 | -0.410 | 2.11e-03 |
| EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS | 31 | 8.23e-05 | -0.409 | 1.43e-03 |
| ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM | 12 | 1.44e-02 | 0.408 | 8.80e-02 |
| ANTIGEN PROCESSING CROSS PRESENTATION | 97 | 4.26e-12 | 0.407 | 2.79e-10 |
| BRANCHED CHAIN AMINO ACID CATABOLISM | 21 | 1.25e-03 | 0.407 | 1.22e-02 |
| KERATAN SULFATE DEGRADATION | 12 | 1.48e-02 | 0.407 | 8.82e-02 |
| METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES | 21 | 1.35e-03 | 0.404 | 1.29e-02 |
| CS DS DEGRADATION | 14 | 9.46e-03 | 0.401 | 6.56e-02 |
| ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES | 10 | 3.05e-02 | -0.395 | 1.47e-01 |
| PHASE 0 RAPID DEPOLARISATION | 30 | 2.21e-04 | -0.390 | 3.03e-03 |
| G PROTEIN ACTIVATION | 22 | 1.71e-03 | 0.386 | 1.57e-02 |
| NUCLEAR PORE COMPLEX NPC DISASSEMBLY | 32 | 1.58e-04 | -0.386 | 2.41e-03 |
| RIP MEDIATED NFKB ACTIVATION VIA ZBP1 | 15 | 9.87e-03 | 0.385 | 6.76e-02 |
| THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | 22 | 1.96e-03 | 0.381 | 1.75e-02 |
| CRISTAE FORMATION | 31 | 2.40e-04 | 0.381 | 3.21e-03 |
| SUMOYLATION OF SUMOYLATION PROTEINS | 33 | 1.67e-04 | -0.379 | 2.53e-03 |
| ASPARTATE AND ASPARAGINE METABOLISM | 10 | 3.82e-02 | -0.379 | 1.69e-01 |
Results (complete table)
Click HERE to show results for all gene sets
| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| EUKARYOTIC TRANSLATION ELONGATION | 87 | 5.04e-34 | 7.53e-01 | 5.94e-31 |
| SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | 106 | 4.10e-33 | 6.73e-01 | 2.41e-30 |
| RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY | 95 | 7.03e-28 | 6.49e-01 | 1.66e-25 |
| EUKARYOTIC TRANSLATION INITIATION | 114 | 5.60e-31 | 6.27e-01 | 1.65e-28 |
| REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO | 10 | 6.04e-04 | -6.26e-01 | 6.66e-03 |
| YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | 11 | 4.32e-04 | 6.13e-01 | 5.04e-03 |
| ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | 59 | 9.20e-15 | 5.83e-01 | 7.74e-13 |
| SELENOAMINO ACID METABOLISM | 109 | 2.15e-25 | 5.77e-01 | 4.22e-23 |
| ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS | 10 | 2.45e-03 | -5.53e-01 | 2.09e-02 |
| FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | 18 | 7.61e-05 | 5.39e-01 | 1.34e-03 |
| NONSENSE MEDIATED DECAY NMD | 109 | 2.99e-21 | 5.24e-01 | 3.91e-19 |
| COMPLEX I BIOGENESIS | 56 | 1.96e-11 | 5.18e-01 | 1.21e-09 |
| CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | 12 | 1.97e-03 | -5.16e-01 | 1.75e-02 |
| SEROTONIN NEUROTRANSMITTER RELEASE CYCLE | 18 | 1.95e-04 | -5.07e-01 | 2.82e-03 |
| ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS | 10 | 6.11e-03 | -5.01e-01 | 4.50e-02 |
| HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | 10 | 6.11e-03 | -5.01e-01 | 4.50e-02 |
| ENDOSOMAL VACUOLAR PATHWAY | 11 | 4.83e-03 | 4.91e-01 | 3.77e-02 |
| SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX | 13 | 3.16e-03 | 4.73e-01 | 2.65e-02 |
| REGULATION OF EXPRESSION OF SLITS AND ROBOS | 160 | 9.48e-25 | 4.70e-01 | 1.40e-22 |
| RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | 125 | 5.98e-19 | 4.60e-01 | 7.05e-17 |
| RESPIRATORY ELECTRON TRANSPORT | 102 | 1.43e-15 | 4.57e-01 | 1.41e-13 |
| NEUROTOXICITY OF CLOSTRIDIUM TOXINS | 10 | 1.33e-02 | -4.52e-01 | 8.41e-02 |
| HDR THROUGH MMEJ ALT NHEJ | 10 | 1.36e-02 | -4.51e-01 | 8.50e-02 |
| CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND | 10 | 1.45e-02 | -4.46e-01 | 8.80e-02 |
| GLUTATHIONE CONJUGATION | 29 | 5.58e-05 | 4.32e-01 | 1.11e-03 |
| SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | 12 | 9.99e-03 | 4.30e-01 | 6.76e-02 |
| PHASE 4 RESTING MEMBRANE POTENTIAL | 14 | 6.04e-03 | -4.24e-01 | 4.50e-02 |
| DSCAM INTERACTIONS | 10 | 2.07e-02 | -4.23e-01 | 1.13e-01 |
| RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA | 24 | 3.77e-04 | -4.19e-01 | 4.54e-03 |
| CELLULAR RESPONSE TO STARVATION | 146 | 4.58e-18 | 4.15e-01 | 4.90e-16 |
| CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | 46 | 1.19e-06 | 4.14e-01 | 4.39e-05 |
| MITOCHONDRIAL FATTY ACID BETA OXIDATION | 34 | 2.97e-05 | 4.14e-01 | 6.72e-04 |
| TRANSLATION | 286 | 7.32e-33 | 4.10e-01 | 2.87e-30 |
| REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | 29 | 1.33e-04 | -4.10e-01 | 2.11e-03 |
| EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS | 31 | 8.23e-05 | -4.09e-01 | 1.43e-03 |
| ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM | 12 | 1.44e-02 | 4.08e-01 | 8.80e-02 |
| ANTIGEN PROCESSING CROSS PRESENTATION | 97 | 4.26e-12 | 4.07e-01 | 2.79e-10 |
| BRANCHED CHAIN AMINO ACID CATABOLISM | 21 | 1.25e-03 | 4.07e-01 | 1.22e-02 |
| KERATAN SULFATE DEGRADATION | 12 | 1.48e-02 | 4.07e-01 | 8.82e-02 |
| METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES | 21 | 1.35e-03 | 4.04e-01 | 1.29e-02 |
| CS DS DEGRADATION | 14 | 9.46e-03 | 4.01e-01 | 6.56e-02 |
| ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES | 10 | 3.05e-02 | -3.95e-01 | 1.47e-01 |
| PHASE 0 RAPID DEPOLARISATION | 30 | 2.21e-04 | -3.90e-01 | 3.03e-03 |
| G PROTEIN ACTIVATION | 22 | 1.71e-03 | 3.86e-01 | 1.57e-02 |
| NUCLEAR PORE COMPLEX NPC DISASSEMBLY | 32 | 1.58e-04 | -3.86e-01 | 2.41e-03 |
| RIP MEDIATED NFKB ACTIVATION VIA ZBP1 | 15 | 9.87e-03 | 3.85e-01 | 6.76e-02 |
| THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | 22 | 1.96e-03 | 3.81e-01 | 1.75e-02 |
| CRISTAE FORMATION | 31 | 2.40e-04 | 3.81e-01 | 3.21e-03 |
| SUMOYLATION OF SUMOYLATION PROTEINS | 33 | 1.67e-04 | -3.79e-01 | 2.53e-03 |
| ASPARTATE AND ASPARAGINE METABOLISM | 10 | 3.82e-02 | -3.79e-01 | 1.69e-01 |
| LGI ADAM INTERACTIONS | 14 | 1.44e-02 | -3.78e-01 | 8.80e-02 |
| SUMOYLATION OF RNA BINDING PROTEINS | 45 | 1.27e-05 | -3.76e-01 | 3.41e-04 |
| METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS | 11 | 3.09e-02 | 3.76e-01 | 1.47e-01 |
| REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM | 11 | 3.09e-02 | -3.76e-01 | 1.47e-01 |
| NUCLEAR IMPORT OF REV PROTEIN | 32 | 2.50e-04 | -3.74e-01 | 3.23e-03 |
| NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 7.99e-03 | -3.72e-01 | 5.71e-02 |
| INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | 34 | 1.97e-04 | -3.69e-01 | 2.82e-03 |
| ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS | 18 | 6.86e-03 | 3.68e-01 | 4.96e-02 |
| DETOXIFICATION OF REACTIVE OXYGEN SPECIES | 33 | 2.55e-04 | 3.68e-01 | 3.23e-03 |
| GLUTATHIONE SYNTHESIS AND RECYCLING | 11 | 3.47e-02 | 3.68e-01 | 1.60e-01 |
| DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | 23 | 2.40e-03 | -3.66e-01 | 2.08e-02 |
| SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | 11 | 3.59e-02 | -3.65e-01 | 1.62e-01 |
| IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | 21 | 3.85e-03 | 3.64e-01 | 3.13e-02 |
| VOLTAGE GATED POTASSIUM CHANNELS | 39 | 8.42e-05 | -3.64e-01 | 1.44e-03 |
| FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF | 14 | 1.87e-02 | -3.63e-01 | 1.06e-01 |
| STABILIZATION OF P53 | 54 | 4.19e-06 | 3.62e-01 | 1.37e-04 |
| TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS | 41 | 6.39e-05 | -3.61e-01 | 1.18e-03 |
| NS1 MEDIATED EFFECTS ON HOST PATHWAYS | 37 | 1.46e-04 | -3.61e-01 | 2.29e-03 |
| AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA | 53 | 5.58e-06 | 3.61e-01 | 1.69e-04 |
| INFLUENZA INFECTION | 145 | 8.12e-14 | 3.59e-01 | 5.62e-12 |
| ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 1.04e-02 | -3.59e-01 | 6.98e-02 |
| MITOCHONDRIAL TRANSLATION | 93 | 2.58e-09 | 3.57e-01 | 1.32e-07 |
| ACTIVATION OF MATRIX METALLOPROTEINASES | 14 | 2.19e-02 | -3.54e-01 | 1.16e-01 |
| RETINOID CYCLE DISEASE EVENTS | 10 | 5.29e-02 | 3.54e-01 | 2.12e-01 |
| ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | 16 | 1.45e-02 | 3.53e-01 | 8.80e-02 |
| INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS | 35 | 3.21e-04 | -3.51e-01 | 3.90e-03 |
| METABOLISM OF POLYAMINES | 57 | 5.20e-06 | 3.49e-01 | 1.66e-04 |
| DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS | 59 | 3.58e-06 | 3.49e-01 | 1.24e-04 |
| CELLULAR RESPONSE TO HYPOXIA | 72 | 3.09e-07 | 3.49e-01 | 1.26e-05 |
| IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | 48 | 3.57e-05 | 3.45e-01 | 7.78e-04 |
| NEGATIVE REGULATION OF NOTCH4 SIGNALING | 54 | 1.27e-05 | 3.44e-01 | 3.41e-04 |
| DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING | 59 | 5.36e-06 | 3.43e-01 | 1.66e-04 |
| HEDGEHOG LIGAND BIOGENESIS | 61 | 4.20e-06 | 3.41e-01 | 1.37e-04 |
| METABOLISM OF AMINO ACIDS AND DERIVATIVES | 315 | 3.17e-25 | 3.40e-01 | 5.34e-23 |
| TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS | 19 | 1.05e-02 | 3.39e-01 | 7.03e-02 |
| REDUCTION OF CYTOSOLIC CA LEVELS | 11 | 5.17e-02 | -3.39e-01 | 2.08e-01 |
| DEGRADATION OF AXIN | 53 | 2.26e-05 | 3.37e-01 | 5.24e-04 |
| P75NTR REGULATES AXONOGENESIS | 10 | 6.87e-02 | -3.32e-01 | 2.54e-01 |
| DEGRADATION OF DVL | 55 | 2.12e-05 | 3.32e-01 | 5.09e-04 |
| PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | 16 | 2.18e-02 | 3.31e-01 | 1.16e-01 |
| THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT | 172 | 7.99e-14 | 3.30e-01 | 5.62e-12 |
| ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 | 19 | 1.29e-02 | 3.30e-01 | 8.30e-02 |
| REGULATION OF TLR BY ENDOGENOUS LIGAND | 12 | 4.81e-02 | 3.30e-01 | 1.97e-01 |
| ARACHIDONIC ACID METABOLISM | 38 | 4.48e-04 | 3.29e-01 | 5.17e-03 |
| REGULATION OF RUNX3 EXPRESSION AND ACTIVITY | 53 | 3.87e-05 | 3.27e-01 | 8.29e-04 |
| SUMOYLATION OF UBIQUITINYLATION PROTEINS | 37 | 5.98e-04 | -3.26e-01 | 6.64e-03 |
| PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING | 11 | 6.11e-02 | -3.26e-01 | 2.32e-01 |
| THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION | 14 | 3.50e-02 | 3.25e-01 | 1.60e-01 |
| TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA | 34 | 1.04e-03 | -3.25e-01 | 1.03e-02 |
| SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | 16 | 2.56e-02 | -3.22e-01 | 1.33e-01 |
| COMPLEMENT CASCADE | 25 | 5.43e-03 | 3.21e-01 | 4.12e-02 |
| SCF SKP2 MEDIATED DEGRADATION OF P27 P21 | 59 | 2.03e-05 | 3.21e-01 | 4.99e-04 |
| MATURATION OF NUCLEOPROTEIN | 10 | 7.97e-02 | -3.20e-01 | 2.79e-01 |
| RA BIOSYNTHESIS PATHWAY | 12 | 5.56e-02 | 3.19e-01 | 2.20e-01 |
| TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT | 18 | 1.95e-02 | 3.18e-01 | 1.09e-01 |
| SIGNALING BY ROBO RECEPTORS | 205 | 4.74e-15 | 3.18e-01 | 4.30e-13 |
| CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY | 13 | 4.75e-02 | 3.18e-01 | 1.95e-01 |
| RRNA PROCESSING | 194 | 3.16e-14 | 3.16e-01 | 2.48e-12 |
| PROCESSING OF INTRONLESS PRE MRNAS | 19 | 1.74e-02 | -3.15e-01 | 1.00e-01 |
| ASYMMETRIC LOCALIZATION OF PCP PROTEINS | 62 | 2.03e-05 | 3.13e-01 | 4.99e-04 |
| TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | 17 | 2.58e-02 | -3.12e-01 | 1.33e-01 |
| PKA ACTIVATION IN GLUCAGON SIGNALLING | 16 | 3.09e-02 | -3.12e-01 | 1.47e-01 |
| ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING | 10 | 8.98e-02 | -3.10e-01 | 3.02e-01 |
| ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES | 10 | 9.07e-02 | 3.09e-01 | 3.04e-01 |
| RESOLUTION OF D LOOP STRUCTURES | 30 | 3.41e-03 | -3.09e-01 | 2.81e-02 |
| REGULATION OF HMOX1 EXPRESSION AND ACTIVITY | 63 | 2.27e-05 | 3.09e-01 | 5.24e-04 |
| CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE | 11 | 7.64e-02 | -3.09e-01 | 2.74e-01 |
| G BETA GAMMA SIGNALLING THROUGH CDC42 | 18 | 2.34e-02 | 3.09e-01 | 1.24e-01 |
| BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS | 11 | 7.67e-02 | 3.08e-01 | 2.74e-01 |
| SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | 15 | 3.89e-02 | -3.08e-01 | 1.71e-01 |
| DEGRADATION OF GLI1 BY THE PROTEASOME | 57 | 6.30e-05 | 3.06e-01 | 1.18e-03 |
| SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS | 58 | 5.76e-05 | -3.05e-01 | 1.11e-03 |
| ACTIVATION OF BH3 ONLY PROTEINS | 30 | 4.10e-03 | -3.03e-01 | 3.28e-02 |
| ACYL CHAIN REMODELLING OF PC | 16 | 3.71e-02 | 3.01e-01 | 1.66e-01 |
| INTERLEUKIN 6 SIGNALING | 10 | 1.00e-01 | 3.00e-01 | 3.19e-01 |
| INITIAL TRIGGERING OF COMPLEMENT | 11 | 8.48e-02 | 3.00e-01 | 2.90e-01 |
| ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 | 23 | 1.30e-02 | 2.99e-01 | 8.30e-02 |
| SIGNAL AMPLIFICATION | 30 | 4.96e-03 | 2.96e-01 | 3.85e-02 |
| INTERLEUKIN 6 FAMILY SIGNALING | 20 | 2.19e-02 | 2.96e-01 | 1.16e-01 |
| INTERLEUKIN 15 SIGNALING | 12 | 7.77e-02 | -2.94e-01 | 2.77e-01 |
| RHO GTPASES ACTIVATE CIT | 18 | 3.11e-02 | 2.94e-01 | 1.47e-01 |
| MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES | 31 | 4.79e-03 | -2.93e-01 | 3.76e-02 |
| SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL | 13 | 6.78e-02 | -2.93e-01 | 2.52e-01 |
| ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | 25 | 1.14e-02 | 2.92e-01 | 7.52e-02 |
| DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM | 40 | 1.44e-03 | 2.91e-01 | 1.36e-02 |
| PROTEIN METHYLATION | 17 | 3.84e-02 | 2.90e-01 | 1.70e-01 |
| G1 S DNA DAMAGE CHECKPOINTS | 65 | 5.68e-05 | 2.89e-01 | 1.11e-03 |
| LYSINE CATABOLISM | 11 | 9.81e-02 | 2.88e-01 | 3.15e-01 |
| APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | 70 | 3.20e-05 | 2.88e-01 | 7.11e-04 |
| RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES | 20 | 2.65e-02 | -2.87e-01 | 1.34e-01 |
| PHASE 2 PLATEAU PHASE | 12 | 8.89e-02 | -2.84e-01 | 3.01e-01 |
| MOLECULES ASSOCIATED WITH ELASTIC FIBRES | 32 | 5.53e-03 | 2.83e-01 | 4.15e-02 |
| REGULATION OF RAS BY GAPS | 66 | 6.92e-05 | 2.83e-01 | 1.25e-03 |
| GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | 23 | 1.88e-02 | -2.83e-01 | 1.06e-01 |
| CELLULAR RESPONSE TO CHEMICAL STRESS | 151 | 2.07e-09 | 2.83e-01 | 1.11e-07 |
| INCRETIN SYNTHESIS SECRETION AND INACTIVATION | 13 | 7.80e-02 | 2.82e-01 | 2.77e-01 |
| PROCESSIVE SYNTHESIS ON THE LAGGING STRAND | 15 | 5.91e-02 | 2.82e-01 | 2.26e-01 |
| APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS | 81 | 1.24e-05 | 2.81e-01 | 3.41e-04 |
| NUCLEOTIDE LIKE PURINERGIC RECEPTORS | 13 | 7.99e-02 | 2.81e-01 | 2.79e-01 |
| RET SIGNALING | 37 | 3.17e-03 | -2.80e-01 | 2.65e-02 |
| RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS | 83 | 1.08e-05 | 2.80e-01 | 3.10e-04 |
| INTERACTION BETWEEN L1 AND ANKYRINS | 28 | 1.06e-02 | -2.79e-01 | 7.03e-02 |
| ABC TRANSPORTER DISORDERS | 70 | 7.13e-05 | 2.75e-01 | 1.27e-03 |
| REGULATION OF PTEN STABILITY AND ACTIVITY | 67 | 1.09e-04 | 2.73e-01 | 1.81e-03 |
| GLYCOLYSIS | 66 | 1.24e-04 | -2.73e-01 | 2.03e-03 |
| MITOCHONDRIAL PROTEIN IMPORT | 63 | 1.81e-04 | 2.73e-01 | 2.69e-03 |
| NCAM1 INTERACTIONS | 41 | 2.51e-03 | -2.73e-01 | 2.13e-02 |
| PHASE I FUNCTIONALIZATION OF COMPOUNDS | 62 | 2.10e-04 | 2.72e-01 | 2.93e-03 |
| CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY | 84 | 1.75e-05 | 2.71e-01 | 4.48e-04 |
| BIOLOGICAL OXIDATIONS | 126 | 1.57e-07 | 2.71e-01 | 6.61e-06 |
| INTERLEUKIN 7 SIGNALING | 19 | 4.12e-02 | -2.71e-01 | 1.77e-01 |
| PINK1 PRKN MEDIATED MITOPHAGY | 22 | 2.82e-02 | 2.70e-01 | 1.40e-01 |
| NETRIN 1 SIGNALING | 49 | 1.14e-03 | -2.69e-01 | 1.11e-02 |
| FCERI MEDIATED NF KB ACTIVATION | 77 | 4.89e-05 | 2.68e-01 | 9.96e-04 |
| DARPP 32 EVENTS | 23 | 2.65e-02 | -2.67e-01 | 1.34e-01 |
| DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE | 20 | 3.92e-02 | 2.66e-01 | 1.71e-01 |
| HDMS DEMETHYLATE HISTONES | 28 | 1.52e-02 | -2.65e-01 | 9.05e-02 |
| DCC MEDIATED ATTRACTIVE SIGNALING | 14 | 8.68e-02 | -2.64e-01 | 2.96e-01 |
| REGULATION OF RUNX2 EXPRESSION AND ACTIVITY | 69 | 1.51e-04 | 2.64e-01 | 2.34e-03 |
| POTASSIUM CHANNELS | 90 | 1.54e-05 | -2.64e-01 | 4.02e-04 |
| POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION | 26 | 2.01e-02 | -2.63e-01 | 1.11e-01 |
| PHASE II CONJUGATION OF COMPOUNDS | 61 | 3.81e-04 | 2.63e-01 | 4.54e-03 |
| TNFR1 INDUCED PROAPOPTOTIC SIGNALING | 12 | 1.16e-01 | 2.62e-01 | 3.56e-01 |
| PEROXISOMAL PROTEIN IMPORT | 57 | 6.17e-04 | 2.62e-01 | 6.73e-03 |
| BETA CATENIN PHOSPHORYLATION CASCADE | 16 | 7.03e-02 | -2.61e-01 | 2.58e-01 |
| SULFUR AMINO ACID METABOLISM | 22 | 3.43e-02 | 2.61e-01 | 1.59e-01 |
| IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS | 14 | 9.22e-02 | 2.60e-01 | 3.08e-01 |
| THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT | 66 | 2.67e-04 | 2.60e-01 | 3.34e-03 |
| FATTY ACID METABOLISM | 145 | 7.12e-08 | 2.59e-01 | 3.23e-06 |
| PURINE CATABOLISM | 16 | 7.25e-02 | 2.59e-01 | 2.65e-01 |
| NUCLEOBASE CATABOLISM | 31 | 1.30e-02 | 2.58e-01 | 8.30e-02 |
| SUMOYLATION OF DNA REPLICATION PROTEINS | 42 | 3.93e-03 | -2.57e-01 | 3.17e-02 |
| MISMATCH REPAIR | 14 | 9.61e-02 | 2.57e-01 | 3.12e-01 |
| CYTOPROTECTION BY HMOX1 | 119 | 1.37e-06 | 2.56e-01 | 4.88e-05 |
| CAMK IV MEDIATED PHOSPHORYLATION OF CREB | 10 | 1.62e-01 | -2.56e-01 | 4.31e-01 |
| G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | 23 | 3.49e-02 | 2.54e-01 | 1.60e-01 |
| SUMOYLATION OF DNA METHYLATION PROTEINS | 16 | 8.02e-02 | -2.53e-01 | 2.79e-01 |
| PEROXISOMAL LIPID METABOLISM | 26 | 2.63e-02 | 2.52e-01 | 1.34e-01 |
| SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS | 73 | 2.04e-04 | -2.52e-01 | 2.89e-03 |
| TRAFFICKING OF AMPA RECEPTORS | 31 | 1.58e-02 | -2.51e-01 | 9.28e-02 |
| PCP CE PATHWAY | 89 | 4.91e-05 | 2.49e-01 | 9.96e-04 |
| SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 | 12 | 1.35e-01 | 2.49e-01 | 3.92e-01 |
| TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY | 29 | 2.10e-02 | 2.48e-01 | 1.14e-01 |
| TRANSCRIPTIONAL REGULATION BY RUNX3 | 92 | 4.41e-05 | 2.46e-01 | 9.28e-04 |
| DISEASES OF IMMUNE SYSTEM | 24 | 3.71e-02 | 2.46e-01 | 1.66e-01 |
| FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES | 15 | 9.95e-02 | 2.46e-01 | 3.19e-01 |
| AURKA ACTIVATION BY TPX2 | 71 | 3.88e-04 | -2.44e-01 | 4.57e-03 |
| IRAK4 DEFICIENCY TLR2 4 | 13 | 1.30e-01 | 2.43e-01 | 3.81e-01 |
| COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING | 35 | 1.32e-02 | 2.42e-01 | 8.38e-02 |
| DAG AND IP3 SIGNALING | 40 | 8.13e-03 | -2.42e-01 | 5.77e-02 |
| FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES | 16 | 9.40e-02 | 2.42e-01 | 3.11e-01 |
| METHYLATION | 12 | 1.48e-01 | 2.41e-01 | 4.11e-01 |
| SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX | 12 | 1.48e-01 | 2.41e-01 | 4.11e-01 |
| RNA POLYMERASE I TRANSCRIPTION TERMINATION | 31 | 2.05e-02 | 2.40e-01 | 1.13e-01 |
| DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | 79 | 2.28e-04 | 2.40e-01 | 3.08e-03 |
| CHONDROITIN SULFATE BIOSYNTHESIS | 18 | 7.86e-02 | 2.39e-01 | 2.77e-01 |
| ASSEMBLY OF THE PRE REPLICATIVE COMPLEX | 64 | 9.38e-04 | 2.39e-01 | 9.44e-03 |
| HEDGEHOG ON STATE | 82 | 1.82e-04 | 2.39e-01 | 2.69e-03 |
| DEGRADATION OF CYSTEINE AND HOMOCYSTEINE | 12 | 1.52e-01 | 2.39e-01 | 4.18e-01 |
| APOPTOSIS INDUCED DNA FRAGMENTATION | 10 | 1.91e-01 | -2.39e-01 | 4.72e-01 |
| PKA MEDIATED PHOSPHORYLATION OF CREB | 19 | 7.21e-02 | -2.38e-01 | 2.64e-01 |
| REGULATION OF TNFR1 SIGNALING | 34 | 1.63e-02 | 2.38e-01 | 9.53e-02 |
| ORC1 REMOVAL FROM CHROMATIN | 67 | 7.79e-04 | 2.37e-01 | 8.18e-03 |
| PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS | 19 | 7.36e-02 | 2.37e-01 | 2.67e-01 |
| NUCLEAR ENVELOPE BREAKDOWN | 49 | 4.26e-03 | -2.36e-01 | 3.39e-02 |
| SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS | 15 | 1.13e-01 | -2.36e-01 | 3.52e-01 |
| POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | 59 | 1.73e-03 | -2.36e-01 | 1.58e-02 |
| GLUCOSE METABOLISM | 80 | 2.74e-04 | -2.35e-01 | 3.39e-03 |
| TNFR2 NON CANONICAL NF KB PATHWAY | 80 | 2.93e-04 | 2.34e-01 | 3.59e-03 |
| VIRAL MESSENGER RNA SYNTHESIS | 42 | 8.62e-03 | -2.34e-01 | 6.01e-02 |
| TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 | 12 | 1.61e-01 | 2.34e-01 | 4.31e-01 |
| ELASTIC FIBRE FORMATION | 38 | 1.28e-02 | 2.33e-01 | 8.30e-02 |
| DEREGULATED CDK5 TRIGGERS MULTIPLE NEURODEGENERATIVE PATHWAYS IN ALZHEIMER S DISEASE MODELS | 19 | 7.87e-02 | -2.33e-01 | 2.77e-01 |
| REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS | 15 | 1.19e-01 | -2.33e-01 | 3.61e-01 |
| ADENYLATE CYCLASE ACTIVATING PATHWAY | 10 | 2.03e-01 | -2.33e-01 | 4.93e-01 |
| ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA | 15 | 1.19e-01 | -2.33e-01 | 3.61e-01 |
| CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND | 13 | 1.46e-01 | 2.33e-01 | 4.11e-01 |
| FGFR2 ALTERNATIVE SPLICING | 25 | 4.43e-02 | 2.32e-01 | 1.87e-01 |
| MAPK6 MAPK4 SIGNALING | 83 | 2.53e-04 | 2.32e-01 | 3.23e-03 |
| UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION | 21 | 6.60e-02 | -2.32e-01 | 2.48e-01 |
| COLLAGEN CHAIN TRIMERIZATION | 40 | 1.14e-02 | -2.31e-01 | 7.52e-02 |
| REGULATION OF GENE EXPRESSION IN BETA CELLS | 10 | 2.08e-01 | -2.30e-01 | 4.97e-01 |
| O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS | 36 | 1.70e-02 | -2.30e-01 | 9.87e-02 |
| SUMOYLATION OF IMMUNE RESPONSE PROTEINS | 11 | 1.87e-01 | 2.30e-01 | 4.65e-01 |
| REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS | 12 | 1.68e-01 | -2.30e-01 | 4.40e-01 |
| GLYCOSPHINGOLIPID METABOLISM | 38 | 1.46e-02 | 2.29e-01 | 8.82e-02 |
| POLYMERASE SWITCHING | 14 | 1.39e-01 | 2.28e-01 | 4.02e-01 |
| PROTEIN LOCALIZATION | 156 | 1.14e-06 | 2.26e-01 | 4.34e-05 |
| NF KB IS ACTIVATED AND SIGNALS SURVIVAL | 13 | 1.59e-01 | 2.26e-01 | 4.31e-01 |
| FORMATION OF APOPTOSOME | 10 | 2.17e-01 | 2.25e-01 | 5.11e-01 |
| SEMA3A PAK DEPENDENT AXON REPULSION | 16 | 1.19e-01 | -2.25e-01 | 3.61e-01 |
| RAS PROCESSING | 24 | 5.86e-02 | 2.23e-01 | 2.25e-01 |
| CGMP EFFECTS | 15 | 1.35e-01 | -2.23e-01 | 3.92e-01 |
| SIGNALING BY NOTCH4 | 83 | 4.61e-04 | 2.22e-01 | 5.28e-03 |
| GLUCAGON TYPE LIGAND RECEPTORS | 25 | 5.44e-02 | 2.22e-01 | 2.16e-01 |
| TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES | 11 | 2.07e-01 | -2.20e-01 | 4.97e-01 |
| RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES | 78 | 7.92e-04 | -2.20e-01 | 8.18e-03 |
| COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING | 26 | 5.40e-02 | 2.18e-01 | 2.15e-01 |
| NCAM SIGNALING FOR NEURITE OUT GROWTH | 61 | 3.22e-03 | -2.18e-01 | 2.67e-02 |
| CLEC7A DECTIN 1 SIGNALING | 95 | 2.46e-04 | 2.18e-01 | 3.23e-03 |
| DNA REPLICATION PRE INITIATION | 79 | 8.27e-04 | 2.18e-01 | 8.40e-03 |
| INTERLEUKIN 1 SIGNALING | 96 | 2.49e-04 | 2.16e-01 | 3.23e-03 |
| CA DEPENDENT EVENTS | 36 | 2.47e-02 | -2.16e-01 | 1.29e-01 |
| CARDIAC CONDUCTION | 109 | 9.65e-05 | -2.16e-01 | 1.62e-03 |
| PD 1 SIGNALING | 10 | 2.38e-01 | 2.16e-01 | 5.32e-01 |
| ANTIMICROBIAL PEPTIDES | 20 | 9.61e-02 | 2.15e-01 | 3.12e-01 |
| SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES | 29 | 4.54e-02 | 2.15e-01 | 1.89e-01 |
| TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS | 13 | 1.82e-01 | -2.14e-01 | 4.59e-01 |
| UCH PROTEINASES | 89 | 5.09e-04 | 2.13e-01 | 5.71e-03 |
| APOPTOTIC FACTOR MEDIATED RESPONSE | 18 | 1.18e-01 | 2.13e-01 | 3.61e-01 |
| REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | 84 | 8.06e-04 | 2.12e-01 | 8.26e-03 |
| CELL EXTRACELLULAR MATRIX INTERACTIONS | 18 | 1.21e-01 | 2.11e-01 | 3.64e-01 |
| LONG TERM POTENTIATION | 23 | 8.29e-02 | -2.09e-01 | 2.85e-01 |
| RNA POLYMERASE I PROMOTER ESCAPE | 48 | 1.28e-02 | 2.08e-01 | 8.30e-02 |
| GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | 19 | 1.18e-01 | -2.07e-01 | 3.61e-01 |
| METABOLISM OF STEROID HORMONES | 22 | 9.31e-02 | 2.07e-01 | 3.09e-01 |
| INTERLEUKIN 12 SIGNALING | 37 | 2.98e-02 | 2.06e-01 | 1.45e-01 |
| PRC2 METHYLATES HISTONES AND DNA | 30 | 5.07e-02 | 2.06e-01 | 2.05e-01 |
| SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | 11 | 2.38e-01 | 2.06e-01 | 5.32e-01 |
| UPTAKE AND ACTIONS OF BACTERIAL TOXINS | 29 | 5.61e-02 | -2.05e-01 | 2.21e-01 |
| BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS | 12 | 2.22e-01 | 2.03e-01 | 5.13e-01 |
| ACTIVATION OF RAC1 | 13 | 2.05e-01 | -2.03e-01 | 4.94e-01 |
| ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY | 10 | 2.66e-01 | 2.03e-01 | 5.63e-01 |
| HYALURONAN UPTAKE AND DEGRADATION | 11 | 2.44e-01 | 2.03e-01 | 5.41e-01 |
| C TYPE LECTIN RECEPTORS CLRS | 112 | 2.12e-04 | 2.03e-01 | 2.93e-03 |
| DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | 23 | 9.28e-02 | -2.02e-01 | 3.09e-01 |
| DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX | 82 | 1.54e-03 | 2.02e-01 | 1.44e-02 |
| NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | 20 | 1.19e-01 | -2.01e-01 | 3.61e-01 |
| SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE | 86 | 1.29e-03 | 2.01e-01 | 1.24e-02 |
| ABC FAMILY PROTEINS MEDIATED TRANSPORT | 94 | 7.84e-04 | 2.01e-01 | 8.18e-03 |
| NEURONAL SYSTEM | 368 | 4.41e-11 | -2.00e-01 | 2.60e-09 |
| DERMATAN SULFATE BIOSYNTHESIS | 11 | 2.52e-01 | 2.00e-01 | 5.50e-01 |
| TCR SIGNALING | 102 | 5.03e-04 | 1.99e-01 | 5.70e-03 |
| TRNA PROCESSING IN THE NUCLEUS | 56 | 9.98e-03 | -1.99e-01 | 6.76e-02 |
| REGULATION OF BETA CELL DEVELOPMENT | 28 | 6.89e-02 | -1.99e-01 | 2.54e-01 |
| ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | 11 | 2.54e-01 | 1.99e-01 | 5.50e-01 |
| PLATELET CALCIUM HOMEOSTASIS | 26 | 8.05e-02 | -1.98e-01 | 2.79e-01 |
| PROLACTIN RECEPTOR SIGNALING | 12 | 2.35e-01 | 1.98e-01 | 5.31e-01 |
| BETA CATENIN INDEPENDENT WNT SIGNALING | 138 | 6.36e-05 | 1.97e-01 | 1.18e-03 |
| SIGNALING BY CSF3 G CSF | 29 | 6.76e-02 | 1.96e-01 | 2.52e-01 |
| RHOH GTPASE CYCLE | 37 | 3.92e-02 | 1.96e-01 | 1.71e-01 |
| FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | 19 | 1.41e-01 | 1.95e-01 | 4.02e-01 |
| REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA | 13 | 2.24e-01 | 1.95e-01 | 5.14e-01 |
| ACYL CHAIN REMODELLING OF PE | 16 | 1.77e-01 | 1.95e-01 | 4.52e-01 |
| RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | 85 | 1.91e-03 | -1.95e-01 | 1.72e-02 |
| GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION | 32 | 5.70e-02 | 1.94e-01 | 2.23e-01 |
| GLYCOGEN SYNTHESIS | 14 | 2.08e-01 | 1.94e-01 | 4.97e-01 |
| GLYCOGEN METABOLISM | 25 | 9.27e-02 | 1.94e-01 | 3.09e-01 |
| TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX | 17 | 1.67e-01 | 1.93e-01 | 4.38e-01 |
| INFLAMMASOMES | 19 | 1.44e-01 | 1.93e-01 | 4.09e-01 |
| REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION | 85 | 2.07e-03 | -1.93e-01 | 1.82e-02 |
| INACTIVATION OF CSF3 G CSF SIGNALING | 24 | 1.01e-01 | 1.93e-01 | 3.22e-01 |
| ADHERENS JUNCTIONS INTERACTIONS | 30 | 6.77e-02 | -1.93e-01 | 2.52e-01 |
| EFFECTS OF PIP2 HYDROLYSIS | 27 | 8.73e-02 | -1.90e-01 | 2.97e-01 |
| CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 | 11 | 2.77e-01 | 1.89e-01 | 5.76e-01 |
| THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | 28 | 8.29e-02 | 1.89e-01 | 2.85e-01 |
| RNA POLYMERASE I TRANSCRIPTION | 68 | 6.96e-03 | 1.89e-01 | 5.00e-02 |
| PI METABOLISM | 79 | 3.68e-03 | -1.89e-01 | 3.01e-02 |
| KERATAN SULFATE KERATIN METABOLISM | 30 | 7.40e-02 | 1.88e-01 | 2.68e-01 |
| TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 | 15 | 2.06e-01 | 1.88e-01 | 4.97e-01 |
| COLLAGEN DEGRADATION | 51 | 2.00e-02 | -1.88e-01 | 1.11e-01 |
| FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES | 24 | 1.11e-01 | 1.88e-01 | 3.46e-01 |
| NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS | 11 | 2.82e-01 | 1.87e-01 | 5.79e-01 |
| TRANSCRIPTIONAL REGULATION BY RUNX2 | 109 | 7.46e-04 | 1.87e-01 | 7.92e-03 |
| SYNAPTIC ADHESION LIKE MOLECULES | 21 | 1.40e-01 | -1.86e-01 | 4.02e-01 |
| CYTOCHROME C MEDIATED APOPTOTIC RESPONSE | 12 | 2.69e-01 | 1.84e-01 | 5.66e-01 |
| DNA METHYLATION | 21 | 1.45e-01 | 1.84e-01 | 4.09e-01 |
| ACYL CHAIN REMODELLING OF PG | 10 | 3.22e-01 | 1.81e-01 | 6.14e-01 |
| ERK MAPK TARGETS | 22 | 1.44e-01 | -1.80e-01 | 4.09e-01 |
| REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION | 10 | 3.25e-01 | 1.80e-01 | 6.14e-01 |
| TRAF6 MEDIATED NF KB ACTIVATION | 22 | 1.45e-01 | 1.79e-01 | 4.09e-01 |
| FRS MEDIATED FGFR4 SIGNALING | 14 | 2.46e-01 | 1.79e-01 | 5.43e-01 |
| INTERLEUKIN 1 FAMILY SIGNALING | 122 | 6.42e-04 | 1.79e-01 | 6.94e-03 |
| TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS | 45 | 3.80e-02 | 1.79e-01 | 1.69e-01 |
| ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | 73 | 8.27e-03 | -1.79e-01 | 5.83e-02 |
| LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME | 13 | 2.64e-01 | -1.79e-01 | 5.62e-01 |
| SEMA4D IN SEMAPHORIN SIGNALING | 24 | 1.30e-01 | 1.79e-01 | 3.81e-01 |
| TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY | 12 | 2.85e-01 | 1.78e-01 | 5.79e-01 |
| ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 | 10 | 3.29e-01 | 1.78e-01 | 6.16e-01 |
| METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION | 15 | 2.33e-01 | 1.78e-01 | 5.27e-01 |
| MITOCHONDRIAL TRNA AMINOACYLATION | 21 | 1.59e-01 | 1.77e-01 | 4.31e-01 |
| PREGNENOLONE BIOSYNTHESIS | 12 | 2.89e-01 | 1.77e-01 | 5.85e-01 |
| BBSOME MEDIATED CARGO TARGETING TO CILIUM | 23 | 1.43e-01 | 1.76e-01 | 4.08e-01 |
| INTERFERON ALPHA BETA SIGNALING | 55 | 2.39e-02 | 1.76e-01 | 1.26e-01 |
| ERKS ARE INACTIVATED | 13 | 2.72e-01 | -1.76e-01 | 5.71e-01 |
| TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX | 30 | 9.55e-02 | 1.76e-01 | 3.12e-01 |
| GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION | 12 | 2.93e-01 | -1.75e-01 | 5.89e-01 |
| ANCHORING FIBRIL FORMATION | 14 | 2.56e-01 | -1.75e-01 | 5.50e-01 |
| G PROTEIN MEDIATED EVENTS | 52 | 2.90e-02 | -1.75e-01 | 1.43e-01 |
| SHC MEDIATED CASCADE FGFR4 | 12 | 2.94e-01 | 1.75e-01 | 5.90e-01 |
| NEUTROPHIL DEGRANULATION | 389 | 4.25e-09 | 1.74e-01 | 2.09e-07 |
| TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS | 10 | 3.43e-01 | -1.73e-01 | 6.27e-01 |
| CELL CELL JUNCTION ORGANIZATION | 49 | 3.61e-02 | -1.73e-01 | 1.62e-01 |
| JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | 22 | 1.60e-01 | -1.73e-01 | 4.31e-01 |
| MATURATION OF SARS COV 2 SPIKE PROTEIN | 29 | 1.08e-01 | 1.73e-01 | 3.38e-01 |
| SIGNALING BY NTRKS | 130 | 7.20e-04 | -1.72e-01 | 7.71e-03 |
| PLASMA LIPOPROTEIN REMODELING | 17 | 2.21e-01 | -1.72e-01 | 5.13e-01 |
| DEFECTS IN VITAMIN AND COFACTOR METABOLISM | 21 | 1.74e-01 | 1.71e-01 | 4.45e-01 |
| PLASMA LIPOPROTEIN ASSEMBLY | 13 | 2.85e-01 | 1.71e-01 | 5.79e-01 |
| B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION | 48 | 4.07e-02 | 1.71e-01 | 1.76e-01 |
| CD28 DEPENDENT VAV1 PATHWAY | 11 | 3.29e-01 | 1.70e-01 | 6.16e-01 |
| G1 S SPECIFIC TRANSCRIPTION | 26 | 1.36e-01 | 1.69e-01 | 3.93e-01 |
| SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | 52 | 3.56e-02 | -1.68e-01 | 1.62e-01 |
| ION HOMEOSTASIS | 49 | 4.16e-02 | -1.68e-01 | 1.78e-01 |
| TRANSMISSION ACROSS CHEMICAL SYNAPSES | 240 | 7.80e-06 | -1.68e-01 | 2.30e-04 |
| ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | 38 | 7.44e-02 | 1.67e-01 | 2.68e-01 |
| DISEASES OF CARBOHYDRATE METABOLISM | 28 | 1.26e-01 | 1.67e-01 | 3.74e-01 |
| NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION | 21 | 1.85e-01 | -1.67e-01 | 4.64e-01 |
| ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION | 26 | 1.41e-01 | 1.67e-01 | 4.02e-01 |
| CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | 33 | 9.72e-02 | 1.67e-01 | 3.14e-01 |
| SPHINGOLIPID METABOLISM | 80 | 9.97e-03 | 1.67e-01 | 6.76e-02 |
| SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS | 18 | 2.22e-01 | -1.66e-01 | 5.13e-01 |
| ADENYLATE CYCLASE INHIBITORY PATHWAY | 13 | 2.99e-01 | -1.66e-01 | 5.94e-01 |
| INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | 29 | 1.21e-01 | 1.66e-01 | 3.64e-01 |
| AMYLOID FIBER FORMATION | 59 | 2.72e-02 | 1.66e-01 | 1.37e-01 |
| PYRIMIDINE CATABOLISM | 10 | 3.63e-01 | 1.66e-01 | 6.43e-01 |
| NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION | 179 | 1.32e-04 | -1.66e-01 | 2.11e-03 |
| E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS | 51 | 4.14e-02 | 1.65e-01 | 1.77e-01 |
| NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 12 | 3.24e-01 | 1.64e-01 | 6.14e-01 |
| KSRP KHSRP BINDS AND DESTABILIZES MRNA | 16 | 2.55e-01 | -1.64e-01 | 5.50e-01 |
| ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE | 96 | 5.50e-03 | -1.64e-01 | 4.15e-02 |
| NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION | 59 | 2.98e-02 | -1.64e-01 | 1.45e-01 |
| APC CDC20 MEDIATED DEGRADATION OF NEK2A | 24 | 1.66e-01 | 1.63e-01 | 4.37e-01 |
| SHC1 EVENTS IN EGFR SIGNALING | 11 | 3.49e-01 | 1.63e-01 | 6.30e-01 |
| KERATAN SULFATE BIOSYNTHESIS | 24 | 1.67e-01 | 1.63e-01 | 4.38e-01 |
| DISEASES OF DNA REPAIR | 11 | 3.50e-01 | -1.63e-01 | 6.32e-01 |
| SNRNP ASSEMBLY | 51 | 4.51e-02 | -1.62e-01 | 1.89e-01 |
| REGULATION OF KIT SIGNALING | 16 | 2.62e-01 | -1.62e-01 | 5.58e-01 |
| RECEPTOR MEDIATED MITOPHAGY | 11 | 3.52e-01 | -1.62e-01 | 6.33e-01 |
| DEFECTS IN COBALAMIN B12 METABOLISM | 13 | 3.14e-01 | 1.61e-01 | 6.11e-01 |
| RAP1 SIGNALLING | 15 | 2.81e-01 | -1.61e-01 | 5.79e-01 |
| DNA REPLICATION | 121 | 2.34e-03 | 1.60e-01 | 2.04e-02 |
| PROTEIN UBIQUITINATION | 70 | 2.14e-02 | 1.59e-01 | 1.15e-01 |
| RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | 106 | 4.74e-03 | 1.59e-01 | 3.75e-02 |
| NRAGE SIGNALS DEATH THROUGH JNK | 55 | 4.18e-02 | -1.59e-01 | 1.78e-01 |
| FRS MEDIATED FGFR3 SIGNALING | 15 | 2.88e-01 | 1.58e-01 | 5.84e-01 |
| SIGNALING BY PDGFR IN DISEASE | 20 | 2.21e-01 | -1.58e-01 | 5.13e-01 |
| SIGNALING BY THE B CELL RECEPTOR BCR | 104 | 5.39e-03 | 1.58e-01 | 4.12e-02 |
| ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION | 14 | 3.06e-01 | -1.58e-01 | 6.04e-01 |
| FGFR1 MUTANT RECEPTOR ACTIVATION | 26 | 1.64e-01 | -1.58e-01 | 4.34e-01 |
| RHO GTPASES ACTIVATE KTN1 | 11 | 3.66e-01 | 1.57e-01 | 6.45e-01 |
| SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | 14 | 3.09e-01 | 1.57e-01 | 6.06e-01 |
| MITOTIC G1 PHASE AND G1 S TRANSITION | 140 | 1.40e-03 | 1.57e-01 | 1.33e-02 |
| ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING | 28 | 1.52e-01 | 1.57e-01 | 4.18e-01 |
| RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK | 48 | 6.07e-02 | -1.57e-01 | 2.31e-01 |
| GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER | 24 | 1.85e-01 | 1.56e-01 | 4.64e-01 |
| MITOTIC PROPHASE | 95 | 8.54e-03 | -1.56e-01 | 5.99e-02 |
| POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 63 | 3.21e-02 | 1.56e-01 | 1.51e-01 |
| TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX | 15 | 2.96e-01 | 1.56e-01 | 5.90e-01 |
| RNA POLYMERASE I TRANSCRIPTION INITIATION | 47 | 6.49e-02 | 1.56e-01 | 2.44e-01 |
| MRNA SPLICING MINOR PATHWAY | 52 | 5.33e-02 | 1.55e-01 | 2.13e-01 |
| SCAVENGING BY CLASS A RECEPTORS | 14 | 3.17e-01 | 1.55e-01 | 6.14e-01 |
| DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | 39 | 9.54e-02 | 1.54e-01 | 3.12e-01 |
| ERBB2 REGULATES CELL MOTILITY | 14 | 3.18e-01 | 1.54e-01 | 6.14e-01 |
| INTERLEUKIN 17 SIGNALING | 67 | 2.92e-02 | -1.54e-01 | 1.43e-01 |
| NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 66 | 3.04e-02 | 1.54e-01 | 1.47e-01 |
| PROLONGED ERK ACTIVATION EVENTS | 14 | 3.19e-01 | -1.54e-01 | 6.14e-01 |
| INTERLEUKIN 12 FAMILY SIGNALING | 44 | 7.99e-02 | 1.53e-01 | 2.79e-01 |
| INSULIN PROCESSING | 24 | 1.96e-01 | -1.53e-01 | 4.80e-01 |
| SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | 20 | 2.39e-01 | 1.52e-01 | 5.32e-01 |
| GLYCOGEN STORAGE DISEASES | 12 | 3.62e-01 | 1.52e-01 | 6.42e-01 |
| ATF6 ATF6 ALPHA ACTIVATES CHAPERONES | 12 | 3.62e-01 | 1.52e-01 | 6.42e-01 |
| DAP12 INTERACTIONS | 31 | 1.43e-01 | 1.52e-01 | 4.08e-01 |
| RND2 GTPASE CYCLE | 38 | 1.05e-01 | -1.52e-01 | 3.32e-01 |
| SHC MEDIATED CASCADE FGFR3 | 13 | 3.45e-01 | 1.51e-01 | 6.27e-01 |
| FGFR2 LIGAND BINDING AND ACTIVATION | 12 | 3.65e-01 | 1.51e-01 | 6.44e-01 |
| GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | 14 | 3.28e-01 | 1.51e-01 | 6.16e-01 |
| NEUROTRANSMITTER RELEASE CYCLE | 49 | 6.80e-02 | -1.51e-01 | 2.52e-01 |
| CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | 19 | 2.57e-01 | 1.50e-01 | 5.52e-01 |
| PROTEIN FOLDING | 89 | 1.45e-02 | 1.50e-01 | 8.80e-02 |
| IRAK1 RECRUITS IKK COMPLEX | 14 | 3.32e-01 | 1.50e-01 | 6.19e-01 |
| DEFECTIVE EXT2 CAUSES EXOSTOSES 2 | 14 | 3.34e-01 | 1.49e-01 | 6.19e-01 |
| REPRESSION OF WNT TARGET GENES | 14 | 3.36e-01 | 1.48e-01 | 6.21e-01 |
| NUCLEOBASE BIOSYNTHESIS | 15 | 3.21e-01 | -1.48e-01 | 6.14e-01 |
| REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE | 75 | 2.71e-02 | -1.48e-01 | 1.37e-01 |
| RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR | 20 | 2.54e-01 | -1.47e-01 | 5.50e-01 |
| HYALURONAN METABOLISM | 15 | 3.24e-01 | 1.47e-01 | 6.14e-01 |
| REGULATION OF MECP2 EXPRESSION AND ACTIVITY | 30 | 1.64e-01 | -1.47e-01 | 4.34e-01 |
| STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS | 10 | 4.21e-01 | -1.47e-01 | 6.96e-01 |
| CELLULAR RESPONSES TO EXTERNAL STIMULI | 603 | 1.01e-09 | 1.46e-01 | 5.64e-08 |
| TRP CHANNELS | 18 | 2.84e-01 | -1.46e-01 | 5.79e-01 |
| OLFACTORY SIGNALING PATHWAY | 27 | 1.89e-01 | -1.46e-01 | 4.70e-01 |
| SIGNALING BY FGFR2 | 63 | 4.54e-02 | 1.46e-01 | 1.89e-01 |
| S PHASE | 153 | 1.90e-03 | 1.46e-01 | 1.72e-02 |
| INTERLEUKIN 35 SIGNALLING | 10 | 4.25e-01 | -1.46e-01 | 6.99e-01 |
| RHOU GTPASE CYCLE | 33 | 1.48e-01 | -1.45e-01 | 4.11e-01 |
| CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION | 11 | 4.05e-01 | -1.45e-01 | 6.82e-01 |
| NGF STIMULATED TRANSCRIPTION | 37 | 1.27e-01 | -1.45e-01 | 3.78e-01 |
| SLC TRANSPORTER DISORDERS | 76 | 2.91e-02 | -1.45e-01 | 1.43e-01 |
| SUMOYLATION OF INTRACELLULAR RECEPTORS | 27 | 1.93e-01 | 1.45e-01 | 4.75e-01 |
| SIGNALING BY PDGF | 57 | 5.89e-02 | -1.45e-01 | 2.26e-01 |
| CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING | 28 | 1.85e-01 | -1.45e-01 | 4.64e-01 |
| INTERLEUKIN 2 FAMILY SIGNALING | 33 | 1.51e-01 | -1.45e-01 | 4.17e-01 |
| FCERI MEDIATED MAPK ACTIVATION | 28 | 1.87e-01 | -1.44e-01 | 4.65e-01 |
| G PROTEIN BETA GAMMA SIGNALLING | 30 | 1.72e-01 | 1.44e-01 | 4.43e-01 |
| SYNTHESIS OF PC | 26 | 2.04e-01 | 1.44e-01 | 4.93e-01 |
| HEME SIGNALING | 45 | 9.53e-02 | -1.44e-01 | 3.12e-01 |
| NEGATIVE REGULATION OF MAPK PATHWAY | 42 | 1.07e-01 | -1.44e-01 | 3.38e-01 |
| INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION | 13 | 3.71e-01 | 1.43e-01 | 6.49e-01 |
| BILE ACID AND BILE SALT METABOLISM | 24 | 2.26e-01 | 1.43e-01 | 5.16e-01 |
| TNF SIGNALING | 43 | 1.05e-01 | 1.43e-01 | 3.32e-01 |
| MITOTIC PROMETAPHASE | 178 | 1.04e-03 | -1.43e-01 | 1.03e-02 |
| REGULATION OF IFNG SIGNALING | 13 | 3.76e-01 | 1.42e-01 | 6.54e-01 |
| RND1 GTPASE CYCLE | 38 | 1.32e-01 | -1.41e-01 | 3.83e-01 |
| LAGGING STRAND SYNTHESIS | 20 | 2.74e-01 | 1.41e-01 | 5.72e-01 |
| ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS | 83 | 2.75e-02 | -1.40e-01 | 1.38e-01 |
| ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES | 52 | 8.08e-02 | -1.40e-01 | 2.79e-01 |
| REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | 91 | 2.13e-02 | 1.40e-01 | 1.15e-01 |
| PROTEIN PROTEIN INTERACTIONS AT SYNAPSES | 85 | 2.63e-02 | -1.39e-01 | 1.34e-01 |
| SIGNALING BY FGFR2 IIIA TM | 19 | 2.94e-01 | 1.39e-01 | 5.90e-01 |
| OTHER SEMAPHORIN INTERACTIONS | 19 | 2.97e-01 | -1.38e-01 | 5.90e-01 |
| HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE | 40 | 1.31e-01 | -1.38e-01 | 3.82e-01 |
| INOSITOL PHOSPHATE METABOLISM | 47 | 1.02e-01 | -1.38e-01 | 3.24e-01 |
| ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION | 33 | 1.70e-01 | 1.38e-01 | 4.43e-01 |
| PROCESSING OF CAPPED INTRONLESS PRE MRNA | 28 | 2.07e-01 | -1.38e-01 | 4.97e-01 |
| P75NTR SIGNALS VIA NF KB | 16 | 3.41e-01 | 1.37e-01 | 6.26e-01 |
| SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | 14 | 3.74e-01 | -1.37e-01 | 6.52e-01 |
| POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE | 25 | 2.38e-01 | 1.36e-01 | 5.32e-01 |
| CHROMOSOME MAINTENANCE | 103 | 1.71e-02 | 1.36e-01 | 9.87e-02 |
| ERYTHROPOIETIN ACTIVATES RAS | 13 | 3.97e-01 | 1.36e-01 | 6.72e-01 |
| DEGRADATION OF THE EXTRACELLULAR MATRIX | 108 | 1.53e-02 | -1.35e-01 | 9.05e-02 |
| HEDGEHOG OFF STATE | 106 | 1.63e-02 | 1.35e-01 | 9.53e-02 |
| ABC TRANSPORTERS IN LIPID HOMEOSTASIS | 14 | 3.82e-01 | -1.35e-01 | 6.58e-01 |
| NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 | 11 | 4.39e-01 | 1.35e-01 | 7.11e-01 |
| CYTOSOLIC TRNA AMINOACYLATION | 24 | 2.54e-01 | -1.35e-01 | 5.50e-01 |
| METABOLISM OF FAT SOLUBLE VITAMINS | 35 | 1.71e-01 | 1.34e-01 | 4.43e-01 |
| GP1B IX V ACTIVATION SIGNALLING | 10 | 4.65e-01 | -1.34e-01 | 7.22e-01 |
| RHOV GTPASE CYCLE | 32 | 1.91e-01 | -1.34e-01 | 4.72e-01 |
| EPIGENETIC REGULATION OF GENE EXPRESSION | 104 | 1.92e-02 | 1.33e-01 | 1.08e-01 |
| MITOPHAGY | 29 | 2.16e-01 | 1.33e-01 | 5.11e-01 |
| INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE | 22 | 2.81e-01 | 1.33e-01 | 5.79e-01 |
| NUCLEAR SIGNALING BY ERBB4 | 31 | 2.01e-01 | 1.33e-01 | 4.91e-01 |
| CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | 48 | 1.12e-01 | 1.33e-01 | 3.48e-01 |
| CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA | 59 | 7.88e-02 | 1.32e-01 | 2.77e-01 |
| NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 23 | 2.74e-01 | 1.32e-01 | 5.72e-01 |
| POLO LIKE KINASE MEDIATED EVENTS | 14 | 3.94e-01 | 1.32e-01 | 6.72e-01 |
| P75NTR RECRUITS SIGNALLING COMPLEXES | 13 | 4.11e-01 | 1.32e-01 | 6.87e-01 |
| HDR THROUGH SINGLE STRAND ANNEALING SSA | 36 | 1.73e-01 | -1.31e-01 | 4.43e-01 |
| ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K | 11 | 4.51e-01 | -1.31e-01 | 7.18e-01 |
| TRIGLYCERIDE CATABOLISM | 14 | 3.96e-01 | 1.31e-01 | 6.72e-01 |
| HATS ACETYLATE HISTONES | 93 | 2.91e-02 | -1.31e-01 | 1.43e-01 |
| NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 23 | 2.78e-01 | -1.31e-01 | 5.76e-01 |
| IRE1ALPHA ACTIVATES CHAPERONES | 50 | 1.11e-01 | 1.30e-01 | 3.46e-01 |
| EPHRIN SIGNALING | 19 | 3.25e-01 | -1.30e-01 | 6.14e-01 |
| PECAM1 INTERACTIONS | 12 | 4.35e-01 | 1.30e-01 | 7.07e-01 |
| BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA | 16 | 3.68e-01 | -1.30e-01 | 6.46e-01 |
| SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL | 26 | 2.52e-01 | -1.30e-01 | 5.50e-01 |
| A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | 26 | 2.53e-01 | 1.30e-01 | 5.50e-01 |
| GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | 30 | 2.21e-01 | 1.29e-01 | 5.13e-01 |
| N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | 35 | 1.87e-01 | 1.29e-01 | 4.65e-01 |
| TELOMERE EXTENSION BY TELOMERASE | 22 | 2.96e-01 | 1.29e-01 | 5.90e-01 |
| SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION | 25 | 2.65e-01 | 1.29e-01 | 5.63e-01 |
| METABOLISM OF NUCLEOTIDES | 92 | 3.36e-02 | 1.28e-01 | 1.57e-01 |
| DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX | 41 | 1.56e-01 | 1.28e-01 | 4.23e-01 |
| CRMPS IN SEMA3A SIGNALING | 16 | 3.75e-01 | -1.28e-01 | 6.53e-01 |
| G0 AND EARLY G1 | 24 | 2.81e-01 | 1.27e-01 | 5.79e-01 |
| TELOMERE MAINTENANCE | 79 | 5.13e-02 | 1.27e-01 | 2.07e-01 |
| FOXO MEDIATED TRANSCRIPTION | 58 | 9.53e-02 | 1.27e-01 | 3.12e-01 |
| WNT5A DEPENDENT INTERNALIZATION OF FZD4 | 15 | 3.96e-01 | -1.27e-01 | 6.72e-01 |
| EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION | 27 | 2.55e-01 | 1.26e-01 | 5.50e-01 |
| SIGNALING BY FGFR1 IN DISEASE | 33 | 2.09e-01 | -1.26e-01 | 4.97e-01 |
| CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN | 36 | 1.90e-01 | -1.26e-01 | 4.70e-01 |
| RHO GTPASES ACTIVATE ROCKS | 19 | 3.41e-01 | 1.26e-01 | 6.26e-01 |
| LATE ENDOSOMAL MICROAUTOPHAGY | 32 | 2.19e-01 | 1.26e-01 | 5.12e-01 |
| METABOLISM OF COFACTORS | 19 | 3.45e-01 | 1.25e-01 | 6.27e-01 |
| TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN | 20 | 3.33e-01 | -1.25e-01 | 6.19e-01 |
| DISEASES OF METABOLISM | 198 | 2.43e-03 | 1.25e-01 | 2.09e-02 |
| FERTILIZATION | 13 | 4.36e-01 | -1.25e-01 | 7.07e-01 |
| PEXOPHAGY | 11 | 4.73e-01 | 1.25e-01 | 7.28e-01 |
| ONCOGENE INDUCED SENESCENCE | 32 | 2.22e-01 | 1.25e-01 | 5.13e-01 |
| ASSEMBLY OF THE HIV VIRION | 16 | 3.88e-01 | 1.25e-01 | 6.67e-01 |
| GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION | 25 | 2.82e-01 | 1.24e-01 | 5.79e-01 |
| MUSCLE CONTRACTION | 162 | 6.51e-03 | -1.24e-01 | 4.77e-02 |
| TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE | 19 | 3.51e-01 | -1.24e-01 | 6.32e-01 |
| INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | 19 | 3.55e-01 | 1.23e-01 | 6.35e-01 |
| SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | 18 | 3.68e-01 | -1.23e-01 | 6.46e-01 |
| DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE | 45 | 1.56e-01 | -1.22e-01 | 4.23e-01 |
| GOLGI ASSOCIATED VESICLE BIOGENESIS | 54 | 1.23e-01 | -1.21e-01 | 3.69e-01 |
| INTRAFLAGELLAR TRANSPORT | 52 | 1.31e-01 | 1.21e-01 | 3.83e-01 |
| ORGANIC CATION ANION ZWITTERION TRANSPORT | 12 | 4.70e-01 | 1.21e-01 | 7.25e-01 |
| RUNX3 REGULATES NOTCH SIGNALING | 13 | 4.53e-01 | -1.20e-01 | 7.20e-01 |
| O LINKED GLYCOSYLATION | 84 | 5.70e-02 | -1.20e-01 | 2.23e-01 |
| GENE SILENCING BY RNA | 83 | 5.86e-02 | -1.20e-01 | 2.25e-01 |
| GAP JUNCTION DEGRADATION | 11 | 4.92e-01 | 1.20e-01 | 7.47e-01 |
| PRE NOTCH PROCESSING IN GOLGI | 17 | 3.93e-01 | 1.20e-01 | 6.72e-01 |
| APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B | 21 | 3.45e-01 | 1.19e-01 | 6.27e-01 |
| MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS | 13 | 4.58e-01 | 1.19e-01 | 7.21e-01 |
| INFECTIOUS DISEASE | 733 | 5.39e-08 | 1.18e-01 | 2.54e-06 |
| P75 NTR RECEPTOR MEDIATED SIGNALLING | 94 | 4.73e-02 | -1.18e-01 | 1.95e-01 |
| TCF DEPENDENT SIGNALING IN RESPONSE TO WNT | 178 | 6.67e-03 | 1.18e-01 | 4.85e-02 |
| TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE | 13 | 4.62e-01 | 1.18e-01 | 7.21e-01 |
| PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION | 23 | 3.28e-01 | 1.18e-01 | 6.16e-01 |
| BASIGIN INTERACTIONS | 22 | 3.42e-01 | -1.17e-01 | 6.27e-01 |
| ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS | 19 | 3.78e-01 | 1.17e-01 | 6.55e-01 |
| CELLULAR RESPONSE TO HEAT STRESS | 94 | 5.04e-02 | -1.17e-01 | 2.05e-01 |
| VITAMIN B5 PANTOTHENATE METABOLISM | 15 | 4.33e-01 | -1.17e-01 | 7.05e-01 |
| EARLY PHASE OF HIV LIFE CYCLE | 14 | 4.49e-01 | -1.17e-01 | 7.16e-01 |
| INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING | 77 | 7.64e-02 | 1.17e-01 | 2.74e-01 |
| SIGNALING BY FGFR | 74 | 8.36e-02 | 1.16e-01 | 2.86e-01 |
| SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP | 64 | 1.09e-01 | 1.16e-01 | 3.40e-01 |
| METABOLISM OF RNA | 644 | 5.79e-07 | 1.16e-01 | 2.28e-05 |
| DOWNSTREAM SIGNAL TRANSDUCTION | 29 | 2.83e-01 | -1.15e-01 | 5.79e-01 |
| BIOTIN TRANSPORT AND METABOLISM | 11 | 5.09e-01 | 1.15e-01 | 7.60e-01 |
| SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS | 11 | 5.09e-01 | 1.15e-01 | 7.60e-01 |
| GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION | 38 | 2.23e-01 | 1.14e-01 | 5.13e-01 |
| RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN | 37 | 2.31e-01 | -1.14e-01 | 5.26e-01 |
| RETROGRADE NEUROTROPHIN SIGNALLING | 14 | 4.62e-01 | -1.13e-01 | 7.21e-01 |
| CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | 73 | 9.56e-02 | -1.13e-01 | 3.12e-01 |
| FGFR2 MUTANT RECEPTOR ACTIVATION | 26 | 3.22e-01 | 1.12e-01 | 6.14e-01 |
| SIGNALING BY FLT3 FUSION PROTEINS | 19 | 3.98e-01 | -1.12e-01 | 6.72e-01 |
| INNATE IMMUNE SYSTEM | 784 | 1.22e-07 | 1.12e-01 | 5.33e-06 |
| BUDDING AND MATURATION OF HIV VIRION | 27 | 3.19e-01 | 1.11e-01 | 6.14e-01 |
| L1CAM INTERACTIONS | 109 | 4.59e-02 | -1.11e-01 | 1.90e-01 |
| TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | 79 | 8.94e-02 | -1.11e-01 | 3.02e-01 |
| PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | 12 | 5.09e-01 | -1.10e-01 | 7.60e-01 |
| RHOBTB GTPASE CYCLE | 35 | 2.60e-01 | 1.10e-01 | 5.56e-01 |
| INTRA GOLGI TRAFFIC | 43 | 2.12e-01 | -1.10e-01 | 5.04e-01 |
| SPHINGOLIPID DE NOVO BIOSYNTHESIS | 42 | 2.19e-01 | 1.10e-01 | 5.12e-01 |
| INHIBITION OF DNA RECOMBINATION AT TELOMERE | 36 | 2.58e-01 | 1.09e-01 | 5.53e-01 |
| FRS MEDIATED FGFR2 SIGNALING | 18 | 4.24e-01 | 1.09e-01 | 6.99e-01 |
| APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | 34 | 2.74e-01 | 1.09e-01 | 5.72e-01 |
| FCGR3A MEDIATED IL10 SYNTHESIS | 32 | 2.90e-01 | -1.08e-01 | 5.85e-01 |
| SIGNALLING TO ERKS | 33 | 2.84e-01 | -1.08e-01 | 5.79e-01 |
| NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 11 | 5.37e-01 | -1.08e-01 | 7.71e-01 |
| RHO GTPASES ACTIVATE PAKS | 21 | 3.94e-01 | 1.07e-01 | 6.72e-01 |
| SIGNALING BY HEDGEHOG | 141 | 2.78e-02 | 1.07e-01 | 1.39e-01 |
| TRANSCRIPTIONAL REGULATION BY RUNX1 | 178 | 1.38e-02 | 1.07e-01 | 8.59e-02 |
| SIGNALING BY FGFR3 FUSIONS IN CANCER | 10 | 5.61e-01 | 1.06e-01 | 7.86e-01 |
| CROSSLINKING OF COLLAGEN FIBRILS | 16 | 4.65e-01 | -1.06e-01 | 7.22e-01 |
| PLASMA LIPOPROTEIN CLEARANCE | 28 | 3.34e-01 | 1.06e-01 | 6.19e-01 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 | 19 | 4.27e-01 | 1.05e-01 | 6.99e-01 |
| G2 M CHECKPOINTS | 133 | 3.61e-02 | 1.05e-01 | 1.62e-01 |
| TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | 43 | 2.32e-01 | -1.05e-01 | 5.27e-01 |
| SYNDECAN INTERACTIONS | 27 | 3.46e-01 | 1.05e-01 | 6.28e-01 |
| TRANSCRIPTIONAL REGULATION BY SMALL RNAS | 62 | 1.54e-01 | -1.05e-01 | 4.20e-01 |
| TRNA PROCESSING | 105 | 6.42e-02 | -1.05e-01 | 2.43e-01 |
| SIALIC ACID METABOLISM | 32 | 3.07e-01 | -1.04e-01 | 6.06e-01 |
| IRS MEDIATED SIGNALLING | 39 | 2.60e-01 | -1.04e-01 | 5.56e-01 |
| TBC RABGAPS | 43 | 2.38e-01 | -1.04e-01 | 5.32e-01 |
| ROS AND RNS PRODUCTION IN PHAGOCYTES | 29 | 3.32e-01 | 1.04e-01 | 6.19e-01 |
| EXTENSION OF TELOMERES | 49 | 2.09e-01 | 1.04e-01 | 4.97e-01 |
| TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | 13 | 5.19e-01 | 1.03e-01 | 7.65e-01 |
| RHOBTB2 GTPASE CYCLE | 23 | 3.92e-01 | 1.03e-01 | 6.70e-01 |
| TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | 16 | 4.75e-01 | 1.03e-01 | 7.30e-01 |
| GLYCOSAMINOGLYCAN METABOLISM | 114 | 5.76e-02 | 1.03e-01 | 2.23e-01 |
| SIGNALING BY WNT IN CANCER | 31 | 3.21e-01 | -1.03e-01 | 6.14e-01 |
| PLATELET ADHESION TO EXPOSED COLLAGEN | 12 | 5.37e-01 | 1.03e-01 | 7.71e-01 |
| ENDOGENOUS STEROLS | 21 | 4.15e-01 | 1.03e-01 | 6.92e-01 |
| NUCLEOTIDE SALVAGE | 21 | 4.15e-01 | 1.03e-01 | 6.92e-01 |
| FC EPSILON RECEPTOR FCERI SIGNALING | 124 | 5.02e-02 | 1.02e-01 | 2.04e-01 |
| SYNTHESIS OF PE | 13 | 5.26e-01 | 1.01e-01 | 7.70e-01 |
| AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | 28 | 3.53e-01 | 1.01e-01 | 6.34e-01 |
| GABA RECEPTOR ACTIVATION | 53 | 2.03e-01 | -1.01e-01 | 4.93e-01 |
| CLASS A 1 RHODOPSIN LIKE RECEPTORS | 202 | 1.34e-02 | 1.01e-01 | 8.46e-02 |
| REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | 15 | 4.98e-01 | -1.01e-01 | 7.54e-01 |
| CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | 90 | 9.82e-02 | 1.01e-01 | 3.15e-01 |
| CALNEXIN CALRETICULIN CYCLE | 26 | 3.74e-01 | 1.01e-01 | 6.52e-01 |
| MAP2K AND MAPK ACTIVATION | 36 | 2.96e-01 | 1.01e-01 | 5.90e-01 |
| SENSORY PROCESSING OF SOUND | 62 | 1.72e-01 | -1.00e-01 | 4.43e-01 |
| SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III | 23 | 4.06e-01 | 1.00e-01 | 6.82e-01 |
| LYSOSOME VESICLE BIOGENESIS | 32 | 3.27e-01 | -1.00e-01 | 6.16e-01 |
| PTEN REGULATION | 134 | 4.60e-02 | 9.99e-02 | 1.90e-01 |
| SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS | 12 | 5.50e-01 | -9.96e-02 | 7.79e-01 |
| IRON UPTAKE AND TRANSPORT | 52 | 2.15e-01 | 9.95e-02 | 5.09e-01 |
| SIGNALING BY HIPPO | 20 | 4.44e-01 | -9.89e-02 | 7.15e-01 |
| SIGNALING BY NOTCH | 189 | 1.92e-02 | 9.89e-02 | 1.08e-01 |
| LYSOSPHINGOLIPID AND LPA RECEPTORS | 13 | 5.37e-01 | -9.88e-02 | 7.71e-01 |
| HCMV EARLY EVENTS | 81 | 1.25e-01 | -9.88e-02 | 3.72e-01 |
| GENERATION OF SECOND MESSENGER MOLECULES | 20 | 4.47e-01 | 9.82e-02 | 7.16e-01 |
| CLASS B 2 SECRETIN FAMILY RECEPTORS | 69 | 1.61e-01 | 9.76e-02 | 4.31e-01 |
| TRIGLYCERIDE METABOLISM | 24 | 4.08e-01 | 9.75e-02 | 6.84e-01 |
| RHOJ GTPASE CYCLE | 54 | 2.17e-01 | -9.71e-02 | 5.11e-01 |
| MUCOPOLYSACCHARIDOSES | 11 | 5.78e-01 | 9.68e-02 | 7.97e-01 |
| JOSEPHIN DOMAIN DUBS | 11 | 5.79e-01 | 9.67e-02 | 7.97e-01 |
| SARS COV 2 INFECTION | 65 | 1.79e-01 | 9.64e-02 | 4.54e-01 |
| E2F MEDIATED REGULATION OF DNA REPLICATION | 19 | 4.69e-01 | -9.60e-02 | 7.25e-01 |
| THE PHOTOTRANSDUCTION CASCADE | 21 | 4.48e-01 | -9.57e-02 | 7.16e-01 |
| VEGFR2 MEDIATED CELL PROLIFERATION | 19 | 4.71e-01 | -9.55e-02 | 7.26e-01 |
| TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA | 16 | 5.09e-01 | -9.54e-02 | 7.60e-01 |
| GLUTAMATE AND GLUTAMINE METABOLISM | 13 | 5.52e-01 | -9.52e-02 | 7.80e-01 |
| COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM | 14 | 5.38e-01 | 9.50e-02 | 7.71e-01 |
| SHC1 EVENTS IN ERBB4 SIGNALING | 13 | 5.54e-01 | 9.49e-02 | 7.80e-01 |
| PEPTIDE LIGAND BINDING RECEPTORS | 120 | 7.31e-02 | 9.48e-02 | 2.66e-01 |
| ELEVATION OF CYTOSOLIC CA2 LEVELS | 15 | 5.26e-01 | -9.46e-02 | 7.70e-01 |
| NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS | 52 | 2.39e-01 | 9.44e-02 | 5.32e-01 |
| INTERFERON GAMMA SIGNALING | 77 | 1.53e-01 | 9.42e-02 | 4.19e-01 |
| PYROPTOSIS | 21 | 4.56e-01 | 9.39e-02 | 7.21e-01 |
| ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 | 22 | 4.47e-01 | 9.36e-02 | 7.16e-01 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 | 20 | 4.69e-01 | 9.35e-02 | 7.25e-01 |
| GRB2 EVENTS IN ERBB2 SIGNALING | 15 | 5.31e-01 | 9.34e-02 | 7.71e-01 |
| INSULIN RECEPTOR SIGNALLING CASCADE | 44 | 2.84e-01 | -9.34e-02 | 5.79e-01 |
| NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING | 33 | 3.54e-01 | 9.33e-02 | 6.34e-01 |
| STIMULI SENSING CHANNELS | 74 | 1.66e-01 | -9.31e-02 | 4.37e-01 |
| INFECTION WITH MYCOBACTERIUM TUBERCULOSIS | 24 | 4.30e-01 | 9.31e-02 | 7.02e-01 |
| SHC1 EVENTS IN ERBB2 SIGNALING | 21 | 4.61e-01 | 9.29e-02 | 7.21e-01 |
| CHROMATIN MODIFYING ENZYMES | 219 | 1.82e-02 | -9.27e-02 | 1.04e-01 |
| SIGNALING BY NTRK3 TRKC | 17 | 5.11e-01 | -9.22e-02 | 7.60e-01 |
| SUMOYLATION | 164 | 4.19e-02 | -9.22e-02 | 1.78e-01 |
| TRANS GOLGI NETWORK VESICLE BUDDING | 69 | 1.87e-01 | -9.19e-02 | 4.65e-01 |
| RHOB GTPASE CYCLE | 67 | 1.94e-01 | -9.18e-02 | 4.76e-01 |
| PHOSPHORYLATION OF THE APC C | 17 | 5.13e-01 | 9.16e-02 | 7.61e-01 |
| ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS | 26 | 4.19e-01 | -9.15e-02 | 6.96e-01 |
| TRANSCRIPTIONAL REGULATION BY MECP2 | 59 | 2.25e-01 | -9.14e-02 | 5.15e-01 |
| RHOBTB1 GTPASE CYCLE | 23 | 4.49e-01 | 9.12e-02 | 7.16e-01 |
| DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS | 50 | 2.66e-01 | -9.10e-02 | 5.63e-01 |
| RUNX2 REGULATES BONE DEVELOPMENT | 29 | 3.97e-01 | 9.09e-02 | 6.72e-01 |
| SIGNALING BY LEPTIN | 10 | 6.21e-01 | 9.03e-02 | 8.31e-01 |
| NONHOMOLOGOUS END JOINING NHEJ | 44 | 3.05e-01 | -8.94e-02 | 6.03e-01 |
| DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS | 18 | 5.13e-01 | 8.90e-02 | 7.61e-01 |
| CA2 PATHWAY | 57 | 2.46e-01 | 8.88e-02 | 5.43e-01 |
| REPRODUCTION | 76 | 1.82e-01 | -8.86e-02 | 4.59e-01 |
| REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION | 30 | 4.02e-01 | -8.83e-02 | 6.79e-01 |
| GPVI MEDIATED ACTIVATION CASCADE | 31 | 3.95e-01 | 8.83e-02 | 6.72e-01 |
| TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST | 13 | 5.82e-01 | -8.81e-02 | 7.98e-01 |
| RAB GERANYLGERANYLATION | 57 | 2.52e-01 | -8.78e-02 | 5.50e-01 |
| STRIATED MUSCLE CONTRACTION | 25 | 4.48e-01 | 8.76e-02 | 7.16e-01 |
| SIGNALING BY INTERLEUKINS | 348 | 5.13e-03 | 8.75e-02 | 3.95e-02 |
| RMTS METHYLATE HISTONE ARGININES | 44 | 3.15e-01 | 8.75e-02 | 6.12e-01 |
| SIGNALING BY PTK6 | 50 | 2.85e-01 | 8.74e-02 | 5.79e-01 |
| PEPTIDE HORMONE METABOLISM | 61 | 2.39e-01 | 8.73e-02 | 5.32e-01 |
| RESOLUTION OF SISTER CHROMATID COHESION | 103 | 1.27e-01 | -8.71e-02 | 3.78e-01 |
| SIGNALING BY WNT | 268 | 1.47e-02 | 8.67e-02 | 8.82e-02 |
| MRNA CAPPING | 29 | 4.20e-01 | 8.65e-02 | 6.96e-01 |
| FRS MEDIATED FGFR1 SIGNALING | 17 | 5.42e-01 | 8.54e-02 | 7.75e-01 |
| APOPTOSIS | 164 | 5.94e-02 | 8.54e-02 | 2.27e-01 |
| ACTIVATION OF SMO | 16 | 5.56e-01 | 8.51e-02 | 7.82e-01 |
| SARS COV 1 INFECTION | 48 | 3.09e-01 | 8.50e-02 | 6.06e-01 |
| REGULATION OF BACH1 ACTIVITY | 11 | 6.26e-01 | -8.50e-02 | 8.33e-01 |
| MTORC1 MEDIATED SIGNALLING | 24 | 4.71e-01 | 8.49e-02 | 7.26e-01 |
| DNA DAMAGE RECOGNITION IN GG NER | 38 | 3.67e-01 | -8.47e-02 | 6.45e-01 |
| GAP JUNCTION ASSEMBLY | 21 | 5.03e-01 | 8.45e-02 | 7.57e-01 |
| TIGHT JUNCTION INTERACTIONS | 17 | 5.47e-01 | -8.43e-02 | 7.78e-01 |
| PROCESSING OF SMDT1 | 16 | 5.61e-01 | 8.41e-02 | 7.86e-01 |
| METALLOPROTEASE DUBS | 26 | 4.62e-01 | 8.33e-02 | 7.21e-01 |
| SIGNALING BY ERBB4 | 57 | 2.77e-01 | 8.32e-02 | 5.76e-01 |
| TRANSFERRIN ENDOCYTOSIS AND RECYCLING | 26 | 4.63e-01 | 8.32e-02 | 7.21e-01 |
| DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS | 17 | 5.53e-01 | -8.32e-02 | 7.80e-01 |
| SODIUM CALCIUM EXCHANGERS | 10 | 6.49e-01 | -8.31e-02 | 8.48e-01 |
| PIWI INTERACTING RNA PIRNA BIOGENESIS | 19 | 5.31e-01 | 8.30e-02 | 7.71e-01 |
| TOLL LIKE RECEPTOR 9 TLR9 CASCADE | 91 | 1.71e-01 | -8.30e-02 | 4.43e-01 |
| HCMV LATE EVENTS | 66 | 2.45e-01 | -8.29e-02 | 5.41e-01 |
| INTRINSIC PATHWAY FOR APOPTOSIS | 52 | 3.01e-01 | -8.29e-02 | 5.98e-01 |
| DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA | 63 | 2.56e-01 | 8.28e-02 | 5.50e-01 |
| DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | 13 | 6.05e-01 | -8.28e-02 | 8.15e-01 |
| PLATELET ACTIVATION SIGNALING AND AGGREGATION | 223 | 3.39e-02 | 8.26e-02 | 1.58e-01 |
| FORMATION OF FIBRIN CLOT CLOTTING CASCADE | 21 | 5.14e-01 | 8.24e-02 | 7.61e-01 |
| STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES | 14 | 5.95e-01 | 8.21e-02 | 8.09e-01 |
| TERMINATION OF TRANSLESION DNA SYNTHESIS | 31 | 4.29e-01 | 8.21e-02 | 7.02e-01 |
| TRANSCRIPTIONAL REGULATION BY E2F6 | 34 | 4.09e-01 | 8.19e-02 | 6.84e-01 |
| RHOBTB3 ATPASE CYCLE | 10 | 6.54e-01 | -8.17e-02 | 8.52e-01 |
| TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | 11 | 6.39e-01 | 8.17e-02 | 8.41e-01 |
| ACYL CHAIN REMODELLING OF PS | 14 | 5.97e-01 | 8.15e-02 | 8.11e-01 |
| NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | 12 | 6.27e-01 | 8.11e-02 | 8.33e-01 |
| MEIOSIS | 63 | 2.67e-01 | -8.10e-02 | 5.63e-01 |
| TRANSCRIPTIONAL REGULATION BY VENTX | 35 | 4.09e-01 | 8.07e-02 | 6.84e-01 |
| ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | 30 | 4.45e-01 | 8.06e-02 | 7.16e-01 |
| FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | 119 | 1.29e-01 | -8.06e-02 | 3.80e-01 |
| INWARDLY RECTIFYING K CHANNELS | 31 | 4.40e-01 | -8.02e-02 | 7.12e-01 |
| MITOTIC SPINDLE CHECKPOINT | 98 | 1.73e-01 | -7.98e-02 | 4.43e-01 |
| G ALPHA Z SIGNALLING EVENTS | 45 | 3.56e-01 | 7.95e-02 | 6.36e-01 |
| HIV TRANSCRIPTION INITIATION | 45 | 3.57e-01 | 7.94e-02 | 6.36e-01 |
| SIGNALING BY VEGF | 103 | 1.69e-01 | -7.85e-02 | 4.41e-01 |
| CTLA4 INHIBITORY SIGNALING | 20 | 5.49e-01 | -7.74e-02 | 7.78e-01 |
| RHOQ GTPASE CYCLE | 58 | 3.10e-01 | -7.71e-02 | 6.06e-01 |
| WNT LIGAND BIOGENESIS AND TRAFFICKING | 20 | 5.51e-01 | -7.71e-02 | 7.79e-01 |
| HIV LIFE CYCLE | 143 | 1.14e-01 | -7.66e-02 | 3.53e-01 |
| HS GAG DEGRADATION | 21 | 5.44e-01 | 7.66e-02 | 7.75e-01 |
| MYOGENESIS | 25 | 5.10e-01 | -7.61e-02 | 7.60e-01 |
| INITIATION OF NUCLEAR ENVELOPE NE REFORMATION | 17 | 5.88e-01 | 7.60e-02 | 8.02e-01 |
| NEGATIVE REGULATION OF THE PI3K AKT NETWORK | 94 | 2.04e-01 | -7.59e-02 | 4.93e-01 |
| REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS | 12 | 6.50e-01 | -7.56e-02 | 8.48e-01 |
| VXPX CARGO TARGETING TO CILIUM | 19 | 5.69e-01 | -7.54e-02 | 7.94e-01 |
| HOST INTERACTIONS OF HIV FACTORS | 125 | 1.47e-01 | 7.51e-02 | 4.11e-01 |
| TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS | 31 | 4.69e-01 | -7.51e-02 | 7.25e-01 |
| RORA ACTIVATES GENE EXPRESSION | 18 | 5.81e-01 | 7.51e-02 | 7.97e-01 |
| METABOLISM OF LIPIDS | 614 | 1.58e-03 | 7.50e-02 | 1.47e-02 |
| DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | 26 | 5.10e-01 | -7.47e-02 | 7.60e-01 |
| SEPARATION OF SISTER CHROMATIDS | 167 | 9.69e-02 | 7.45e-02 | 3.14e-01 |
| GPCR LIGAND BINDING | 283 | 3.17e-02 | 7.43e-02 | 1.50e-01 |
| ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK | 28 | 4.97e-01 | -7.42e-02 | 7.52e-01 |
| N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | 24 | 5.30e-01 | -7.41e-02 | 7.70e-01 |
| AMINE LIGAND BINDING RECEPTORS | 31 | 4.77e-01 | -7.38e-02 | 7.32e-01 |
| HS GAG BIOSYNTHESIS | 29 | 4.93e-01 | 7.35e-02 | 7.49e-01 |
| RAF ACTIVATION | 34 | 4.59e-01 | -7.33e-02 | 7.21e-01 |
| MITOCHONDRIAL BIOGENESIS | 92 | 2.27e-01 | 7.30e-02 | 5.17e-01 |
| ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS | 35 | 4.55e-01 | -7.29e-02 | 7.21e-01 |
| TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES | 61 | 3.28e-01 | -7.25e-02 | 6.16e-01 |
| SIGNALING BY KIT IN DISEASE | 20 | 5.76e-01 | -7.22e-02 | 7.97e-01 |
| TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN | 12 | 6.65e-01 | -7.21e-02 | 8.60e-01 |
| EPH EPHRIN MEDIATED REPULSION OF CELLS | 51 | 3.74e-01 | -7.20e-02 | 6.52e-01 |
| ECM PROTEOGLYCANS | 67 | 3.08e-01 | 7.20e-02 | 6.06e-01 |
| GLYCEROPHOSPHOLIPID BIOSYNTHESIS | 107 | 1.99e-01 | 7.19e-02 | 4.87e-01 |
| RHO GTPASES ACTIVATE FORMINS | 120 | 1.74e-01 | -7.19e-02 | 4.45e-01 |
| ACTIVATION OF THE PRE REPLICATIVE COMPLEX | 29 | 5.07e-01 | -7.12e-02 | 7.60e-01 |
| ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING | 21 | 5.73e-01 | -7.10e-02 | 7.97e-01 |
| ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION | 92 | 2.40e-01 | 7.09e-02 | 5.33e-01 |
| VISUAL PHOTOTRANSDUCTION | 62 | 3.35e-01 | 7.08e-02 | 6.19e-01 |
| ACETYLCHOLINE REGULATES INSULIN SECRETION | 10 | 6.98e-01 | -7.08e-02 | 8.79e-01 |
| HEPARAN SULFATE HEPARIN HS GAG METABOLISM | 52 | 3.79e-01 | 7.06e-02 | 6.56e-01 |
| CYTOSOLIC SULFONATION OF SMALL MOLECULES | 15 | 6.37e-01 | 7.04e-02 | 8.40e-01 |
| IRF3 MEDIATED INDUCTION OF TYPE I IFN | 11 | 6.86e-01 | 7.04e-02 | 8.74e-01 |
| CHAPERONE MEDIATED AUTOPHAGY | 21 | 5.78e-01 | 7.02e-02 | 7.97e-01 |
| CLATHRIN MEDIATED ENDOCYTOSIS | 135 | 1.60e-01 | -7.01e-02 | 4.31e-01 |
| REGULATED PROTEOLYSIS OF P75NTR | 12 | 6.75e-01 | 6.99e-02 | 8.67e-01 |
| HSF1 ACTIVATION | 25 | 5.47e-01 | 6.96e-02 | 7.78e-01 |
| EXTRA NUCLEAR ESTROGEN SIGNALING | 67 | 3.25e-01 | 6.95e-02 | 6.14e-01 |
| SHC MEDIATED CASCADE FGFR1 | 15 | 6.41e-01 | 6.95e-02 | 8.43e-01 |
| AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS | 10 | 7.05e-01 | -6.93e-02 | 8.82e-01 |
| SYNTHESIS OF PA | 29 | 5.23e-01 | 6.85e-02 | 7.68e-01 |
| CELL JUNCTION ORGANIZATION | 73 | 3.12e-01 | -6.85e-02 | 6.09e-01 |
| G ALPHA Q SIGNALLING EVENTS | 167 | 1.28e-01 | 6.84e-02 | 3.78e-01 |
| PURINE SALVAGE | 12 | 6.84e-01 | 6.78e-02 | 8.74e-01 |
| P38MAPK EVENTS | 12 | 6.84e-01 | -6.78e-02 | 8.74e-01 |
| SIGNALING BY FGFR2 IN DISEASE | 36 | 4.84e-01 | 6.74e-02 | 7.40e-01 |
| CDC42 GTPASE CYCLE | 152 | 1.55e-01 | -6.69e-02 | 4.22e-01 |
| FORMATION OF THE CORNIFIED ENVELOPE | 30 | 5.28e-01 | -6.66e-02 | 7.70e-01 |
| KERATINIZATION | 30 | 5.28e-01 | -6.66e-02 | 7.70e-01 |
| ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS | 23 | 5.81e-01 | -6.65e-02 | 7.97e-01 |
| FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX | 47 | 4.31e-01 | 6.64e-02 | 7.03e-01 |
| TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS | 44 | 4.48e-01 | 6.61e-02 | 7.16e-01 |
| DNA STRAND ELONGATION | 32 | 5.19e-01 | 6.59e-02 | 7.65e-01 |
| SIGNALING BY RETINOIC ACID | 32 | 5.20e-01 | 6.58e-02 | 7.65e-01 |
| DAP12 SIGNALING | 24 | 5.77e-01 | 6.58e-02 | 7.97e-01 |
| VEGFR2 MEDIATED VASCULAR PERMEABILITY | 27 | 5.57e-01 | 6.54e-02 | 7.82e-01 |
| MEIOTIC SYNAPSIS | 40 | 4.80e-01 | -6.46e-02 | 7.35e-01 |
| COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES | 62 | 3.81e-01 | -6.43e-02 | 6.58e-01 |
| REGULATION OF TP53 ACTIVITY | 150 | 1.79e-01 | -6.37e-02 | 4.54e-01 |
| ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT | 23 | 5.97e-01 | 6.37e-02 | 8.11e-01 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 | 23 | 6.00e-01 | 6.32e-02 | 8.13e-01 |
| INTERLEUKIN RECEPTOR SHC SIGNALING | 20 | 6.25e-01 | -6.31e-02 | 8.33e-01 |
| MITOTIC METAPHASE AND ANAPHASE | 208 | 1.18e-01 | 6.30e-02 | 3.61e-01 |
| INTERLEUKIN 10 SIGNALING | 20 | 6.26e-01 | 6.30e-02 | 8.33e-01 |
| OPIOID SIGNALLING | 86 | 3.13e-01 | -6.30e-02 | 6.11e-01 |
| TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS | 69 | 3.66e-01 | 6.29e-02 | 6.45e-01 |
| RRNA PROCESSING IN THE MITOCHONDRION | 10 | 7.31e-01 | -6.27e-02 | 8.92e-01 |
| CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY | 23 | 6.03e-01 | -6.27e-02 | 8.15e-01 |
| FORMATION OF THE EARLY ELONGATION COMPLEX | 33 | 5.33e-01 | 6.27e-02 | 7.71e-01 |
| IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | 10 | 7.32e-01 | -6.26e-02 | 8.92e-01 |
| DISEASES OF MITOTIC CELL CYCLE | 37 | 5.12e-01 | 6.24e-02 | 7.61e-01 |
| DISEASES OF PROGRAMMED CELL DEATH | 55 | 4.26e-01 | 6.21e-02 | 6.99e-01 |
| RHO GTPASES ACTIVATE PKNS | 48 | 4.58e-01 | 6.20e-02 | 7.21e-01 |
| EPHA MEDIATED GROWTH CONE COLLAPSE | 29 | 5.66e-01 | 6.16e-02 | 7.90e-01 |
| TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX | 12 | 7.13e-01 | 6.13e-02 | 8.86e-01 |
| SIGNALING BY ERYTHROPOIETIN | 24 | 6.05e-01 | -6.10e-02 | 8.15e-01 |
| TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | 74 | 3.64e-01 | 6.10e-02 | 6.44e-01 |
| CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE | 49 | 4.61e-01 | 6.09e-02 | 7.21e-01 |
| DNA DOUBLE STRAND BREAK REPAIR | 136 | 2.21e-01 | -6.08e-02 | 5.13e-01 |
| TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE | 93 | 3.14e-01 | -6.05e-02 | 6.11e-01 |
| UNWINDING OF DNA | 12 | 7.21e-01 | -5.95e-02 | 8.90e-01 |
| SYNTHESIS OF BILE ACIDS AND BILE SALTS | 21 | 6.38e-01 | 5.93e-02 | 8.41e-01 |
| PROGRAMMED CELL DEATH | 186 | 1.64e-01 | 5.93e-02 | 4.34e-01 |
| BLOOD GROUP SYSTEMS BIOSYNTHESIS | 13 | 7.13e-01 | -5.90e-02 | 8.86e-01 |
| MRNA SPLICING | 188 | 1.66e-01 | 5.87e-02 | 4.37e-01 |
| ION CHANNEL TRANSPORT | 140 | 2.32e-01 | -5.86e-02 | 5.27e-01 |
| TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS | 54 | 4.57e-01 | -5.86e-02 | 7.21e-01 |
| CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS | 95 | 3.24e-01 | -5.86e-02 | 6.14e-01 |
| METABOLISM OF FOLATE AND PTERINES | 15 | 6.95e-01 | 5.85e-02 | 8.78e-01 |
| HDR THROUGH HOMOLOGOUS RECOMBINATION HRR | 62 | 4.27e-01 | -5.84e-02 | 6.99e-01 |
| SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R | 44 | 5.04e-01 | -5.83e-02 | 7.58e-01 |
| NUCLEAR ENVELOPE NE REASSEMBLY | 64 | 4.21e-01 | -5.81e-02 | 6.96e-01 |
| GAB1 SIGNALOSOME | 14 | 7.08e-01 | -5.78e-02 | 8.84e-01 |
| RHOD GTPASE CYCLE | 50 | 4.80e-01 | -5.77e-02 | 7.35e-01 |
| GROWTH HORMONE RECEPTOR SIGNALING | 21 | 6.48e-01 | 5.76e-02 | 8.48e-01 |
| SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | 20 | 6.56e-01 | 5.76e-02 | 8.52e-01 |
| REGULATION OF IFNA SIGNALING | 12 | 7.31e-01 | 5.74e-02 | 8.92e-01 |
| DISEASES OF GLYCOSYLATION | 124 | 2.71e-01 | 5.72e-02 | 5.70e-01 |
| THE NLRP3 INFLAMMASOME | 15 | 7.01e-01 | 5.72e-02 | 8.80e-01 |
| RND3 GTPASE CYCLE | 37 | 5.49e-01 | -5.70e-02 | 7.78e-01 |
| DISORDERS OF TRANSMEMBRANE TRANSPORTERS | 146 | 2.39e-01 | 5.66e-02 | 5.32e-01 |
| SIGNALING BY NUCLEAR RECEPTORS | 223 | 1.48e-01 | 5.64e-02 | 4.11e-01 |
| NEDDYLATION | 219 | 1.52e-01 | 5.63e-02 | 4.18e-01 |
| CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX | 10 | 7.58e-01 | -5.63e-02 | 9.04e-01 |
| RESPONSE OF MTB TO PHAGOCYTOSIS | 21 | 6.57e-01 | 5.60e-02 | 8.52e-01 |
| MEMBRANE TRAFFICKING | 583 | 2.15e-02 | -5.59e-02 | 1.16e-01 |
| RHO GTPASES ACTIVATE NADPH OXIDASES | 20 | 6.66e-01 | 5.58e-02 | 8.60e-01 |
| DEADENYLATION OF MRNA | 25 | 6.30e-01 | -5.57e-02 | 8.34e-01 |
| SMOOTH MUSCLE CONTRACTION | 34 | 5.75e-01 | 5.56e-02 | 7.97e-01 |
| LAMININ INTERACTIONS | 29 | 6.06e-01 | -5.53e-02 | 8.15e-01 |
| INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING | 41 | 5.40e-01 | 5.53e-02 | 7.73e-01 |
| COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 44 | 5.28e-01 | -5.50e-02 | 7.70e-01 |
| UPTAKE AND FUNCTION OF ANTHRAX TOXINS | 11 | 7.53e-01 | 5.48e-02 | 9.04e-01 |
| UNFOLDED PROTEIN RESPONSE UPR | 86 | 3.80e-01 | 5.48e-02 | 6.58e-01 |
| SIGNAL TRANSDUCTION BY L1 | 21 | 6.66e-01 | -5.45e-02 | 8.60e-01 |
| NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | 13 | 7.35e-01 | 5.42e-02 | 8.95e-01 |
| RHO GTPASE CYCLE | 425 | 5.74e-02 | -5.39e-02 | 2.23e-01 |
| RAC1 GTPASE CYCLE | 177 | 2.17e-01 | -5.39e-02 | 5.11e-01 |
| SIGNALING BY NTRK2 TRKB | 24 | 6.48e-01 | -5.38e-02 | 8.48e-01 |
| PYRUVATE METABOLISM | 27 | 6.29e-01 | -5.38e-02 | 8.34e-01 |
| PLATELET HOMEOSTASIS | 77 | 4.16e-01 | -5.37e-02 | 6.92e-01 |
| SIGNALING BY ACTIVIN | 12 | 7.49e-01 | -5.34e-02 | 9.04e-01 |
| TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES | 45 | 5.36e-01 | -5.33e-02 | 7.71e-01 |
| VESICLE MEDIATED TRANSPORT | 614 | 2.52e-02 | -5.31e-02 | 1.32e-01 |
| PROCESSING AND ACTIVATION OF SUMO | 10 | 7.71e-01 | 5.31e-02 | 9.06e-01 |
| RHOF GTPASE CYCLE | 40 | 5.62e-01 | -5.31e-02 | 7.86e-01 |
| REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF | 56 | 4.94e-01 | -5.28e-02 | 7.49e-01 |
| HOMOLOGY DIRECTED REPAIR | 107 | 3.48e-01 | -5.26e-02 | 6.29e-01 |
| NERVOUS SYSTEM DEVELOPMENT | 550 | 3.57e-02 | 5.26e-02 | 1.62e-01 |
| RAB REGULATION OF TRAFFICKING | 119 | 3.25e-01 | -5.23e-02 | 6.14e-01 |
| AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | 14 | 7.35e-01 | -5.22e-02 | 8.95e-01 |
| HEME BIOSYNTHESIS | 13 | 7.45e-01 | 5.22e-02 | 9.03e-01 |
| HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR | 48 | 5.32e-01 | -5.22e-02 | 7.71e-01 |
| COPI MEDIATED ANTEROGRADE TRANSPORT | 91 | 3.91e-01 | -5.21e-02 | 6.70e-01 |
| SIGNALING BY NOTCH2 | 33 | 6.06e-01 | 5.19e-02 | 8.15e-01 |
| ENOS ACTIVATION | 11 | 7.66e-01 | 5.18e-02 | 9.05e-01 |
| NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 26 | 6.48e-01 | 5.17e-02 | 8.48e-01 |
| SIGNALLING TO RAS | 19 | 6.98e-01 | -5.15e-02 | 8.79e-01 |
| FATTY ACYL COA BIOSYNTHESIS | 32 | 6.14e-01 | 5.15e-02 | 8.24e-01 |
| SIGNALING BY MET | 75 | 4.42e-01 | 5.14e-02 | 7.13e-01 |
| METABOLISM OF VITAMINS AND COFACTORS | 156 | 2.69e-01 | 5.13e-02 | 5.66e-01 |
| TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | 171 | 2.52e-01 | -5.08e-02 | 5.50e-01 |
| SIGNALING BY FGFR3 | 35 | 6.04e-01 | 5.07e-02 | 8.15e-01 |
| INTERLEUKIN 37 SIGNALING | 18 | 7.10e-01 | 5.05e-02 | 8.85e-01 |
| CYTOKINE SIGNALING IN IMMUNE SYSTEM | 545 | 4.48e-02 | 5.04e-02 | 1.89e-01 |
| TRIGLYCERIDE BIOSYNTHESIS | 10 | 7.83e-01 | 5.03e-02 | 9.12e-01 |
| BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS | 33 | 6.18e-01 | 5.02e-02 | 8.28e-01 |
| NON INTEGRIN MEMBRANE ECM INTERACTIONS | 57 | 5.14e-01 | 5.00e-02 | 7.61e-01 |
| TIE2 SIGNALING | 17 | 7.23e-01 | 4.97e-02 | 8.90e-01 |
| PYRIMIDINE SALVAGE | 10 | 7.87e-01 | 4.94e-02 | 9.14e-01 |
| ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS | 67 | 4.85e-01 | 4.94e-02 | 7.40e-01 |
| RECYCLING PATHWAY OF L1 | 40 | 5.91e-01 | -4.91e-02 | 8.05e-01 |
| SIGNALING BY FGFR4 IN DISEASE | 10 | 7.88e-01 | -4.91e-02 | 9.15e-01 |
| CARNITINE METABOLISM | 14 | 7.51e-01 | 4.91e-02 | 9.04e-01 |
| NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS | 21 | 6.99e-01 | 4.87e-02 | 8.79e-01 |
| REGULATION OF PTEN GENE TRANSCRIPTION | 58 | 5.22e-01 | -4.86e-02 | 7.68e-01 |
| DUAL INCISION IN TC NER | 64 | 5.02e-01 | 4.86e-02 | 7.57e-01 |
| DEADENYLATION DEPENDENT MRNA DECAY | 55 | 5.35e-01 | -4.84e-02 | 7.71e-01 |
| RAB GEFS EXCHANGE GTP FOR GDP ON RABS | 88 | 4.33e-01 | -4.84e-02 | 7.05e-01 |
| SIGNALING BY EGFR IN CANCER | 22 | 6.95e-01 | 4.83e-02 | 8.78e-01 |
| ER TO GOLGI ANTEROGRADE TRANSPORT | 142 | 3.22e-01 | -4.82e-02 | 6.14e-01 |
| SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 | 630 | 3.98e-02 | -4.82e-02 | 1.73e-01 |
| WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 | 13 | 7.64e-01 | 4.81e-02 | 9.05e-01 |
| COLLAGEN FORMATION | 79 | 4.60e-01 | -4.81e-02 | 7.21e-01 |
| KINESINS | 48 | 5.66e-01 | -4.79e-02 | 7.90e-01 |
| TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX | 11 | 7.85e-01 | 4.76e-02 | 9.13e-01 |
| CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION | 347 | 1.29e-01 | 4.75e-02 | 3.80e-01 |
| VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS | 36 | 6.26e-01 | 4.70e-02 | 8.33e-01 |
| MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION | 16 | 7.46e-01 | -4.68e-02 | 9.04e-01 |
| SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER | 15 | 7.54e-01 | 4.68e-02 | 9.04e-01 |
| PI 3K CASCADE FGFR1 | 15 | 7.54e-01 | -4.68e-02 | 9.04e-01 |
| DEATH RECEPTOR SIGNALLING | 133 | 3.58e-01 | -4.62e-02 | 6.36e-01 |
| SIGNALING BY TGF BETA RECEPTOR COMPLEX | 72 | 5.00e-01 | -4.60e-02 | 7.55e-01 |
| EXTRACELLULAR MATRIX ORGANIZATION | 244 | 2.18e-01 | 4.59e-02 | 5.12e-01 |
| DNA REPAIR | 292 | 1.80e-01 | -4.57e-02 | 4.56e-01 |
| SIGNALING BY BMP | 25 | 6.94e-01 | -4.54e-02 | 8.78e-01 |
| PENTOSE PHOSPHATE PATHWAY | 13 | 7.77e-01 | 4.54e-02 | 9.10e-01 |
| INSULIN RECEPTOR RECYCLING | 20 | 7.25e-01 | 4.54e-02 | 8.92e-01 |
| MITOTIC TELOPHASE CYTOKINESIS | 13 | 7.77e-01 | -4.53e-02 | 9.10e-01 |
| CD28 CO STIMULATION | 31 | 6.63e-01 | 4.53e-02 | 8.59e-01 |
| CITRIC ACID CYCLE TCA CYCLE | 22 | 7.14e-01 | 4.51e-02 | 8.86e-01 |
| RHOA GTPASE CYCLE | 142 | 3.54e-01 | -4.51e-02 | 6.34e-01 |
| TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE | 38 | 6.31e-01 | 4.50e-02 | 8.35e-01 |
| NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | 17 | 7.49e-01 | 4.49e-02 | 9.04e-01 |
| ACTIVATION OF AMPK DOWNSTREAM OF NMDARS | 20 | 7.29e-01 | -4.48e-02 | 8.92e-01 |
| MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | 15 | 7.64e-01 | -4.47e-02 | 9.05e-01 |
| ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION | 117 | 4.06e-01 | 4.45e-02 | 6.82e-01 |
| DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS | 366 | 1.45e-01 | 4.45e-02 | 4.09e-01 |
| HIV INFECTION | 221 | 2.56e-01 | 4.44e-02 | 5.50e-01 |
| SIGNALING BY INSULIN RECEPTOR | 63 | 5.44e-01 | -4.42e-02 | 7.75e-01 |
| NEUREXINS AND NEUROLIGINS | 54 | 5.75e-01 | -4.41e-02 | 7.97e-01 |
| PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 | 11 | 8.01e-01 | -4.39e-02 | 9.17e-01 |
| METABOLISM OF STEROIDS | 115 | 4.18e-01 | 4.38e-02 | 6.94e-01 |
| SIGNALING BY EGFR | 47 | 6.04e-01 | 4.37e-02 | 8.15e-01 |
| RNA POLYMERASE II TRANSCRIBES SNRNA GENES | 74 | 5.16e-01 | -4.37e-02 | 7.63e-01 |
| SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS | 41 | 6.30e-01 | 4.36e-02 | 8.34e-01 |
| REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION | 87 | 4.86e-01 | -4.33e-02 | 7.40e-01 |
| RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX | 29 | 6.88e-01 | 4.32e-02 | 8.75e-01 |
| ATTENUATION PHASE | 23 | 7.21e-01 | 4.30e-02 | 8.90e-01 |
| SUMOYLATION OF TRANSCRIPTION FACTORS | 17 | 7.60e-01 | -4.27e-02 | 9.04e-01 |
| SIGNALING BY FGFR4 | 33 | 6.73e-01 | 4.25e-02 | 8.65e-01 |
| RHO GTPASES ACTIVATE IQGAPS | 24 | 7.20e-01 | 4.23e-02 | 8.90e-01 |
| DEVELOPMENTAL BIOLOGY | 821 | 4.04e-02 | 4.23e-02 | 1.75e-01 |
| G ALPHA 12 13 SIGNALLING EVENTS | 74 | 5.29e-01 | 4.23e-02 | 7.70e-01 |
| ESR MEDIATED SIGNALING | 167 | 3.47e-01 | 4.23e-02 | 6.28e-01 |
| CELL CELL COMMUNICATION | 106 | 4.55e-01 | -4.20e-02 | 7.21e-01 |
| CILIUM ASSEMBLY | 192 | 3.20e-01 | -4.17e-02 | 6.14e-01 |
| SENSORY PERCEPTION | 149 | 3.81e-01 | -4.16e-02 | 6.58e-01 |
| COHESIN LOADING ONTO CHROMATIN | 10 | 8.20e-01 | 4.15e-02 | 9.27e-01 |
| SIGNALING BY ERBB2 | 48 | 6.20e-01 | 4.13e-02 | 8.30e-01 |
| GAP JUNCTION TRAFFICKING AND REGULATION | 33 | 6.82e-01 | 4.12e-02 | 8.74e-01 |
| PHOSPHOLIPID METABOLISM | 185 | 3.37e-01 | -4.10e-02 | 6.21e-01 |
| ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | 32 | 6.89e-01 | 4.09e-02 | 8.75e-01 |
| RESOLUTION OF ABASIC SITES AP SITES | 37 | 6.68e-01 | -4.08e-02 | 8.61e-01 |
| ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS | 17 | 7.72e-01 | 4.07e-02 | 9.06e-01 |
| PKMTS METHYLATE HISTONE LYSINES | 49 | 6.27e-01 | -4.01e-02 | 8.33e-01 |
| MISCELLANEOUS TRANSPORT AND BINDING EVENTS | 20 | 7.57e-01 | -4.00e-02 | 9.04e-01 |
| NEGATIVE REGULATION OF MET ACTIVITY | 20 | 7.57e-01 | 4.00e-02 | 9.04e-01 |
| TRAF6 MEDIATED IRF7 ACTIVATION | 15 | 7.90e-01 | 3.98e-02 | 9.15e-01 |
| COPII MEDIATED VESICLE TRANSPORT | 66 | 5.77e-01 | -3.97e-02 | 7.97e-01 |
| MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | 15 | 7.91e-01 | -3.95e-02 | 9.15e-01 |
| LEISHMANIA INFECTION | 197 | 3.41e-01 | 3.94e-02 | 6.26e-01 |
| NICOTINAMIDE SALVAGING | 16 | 7.86e-01 | -3.93e-02 | 9.13e-01 |
| G2 M DNA DAMAGE CHECKPOINT | 66 | 5.84e-01 | -3.90e-02 | 7.98e-01 |
| PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR | 20 | 7.63e-01 | 3.90e-02 | 9.05e-01 |
| NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX | 32 | 7.03e-01 | -3.89e-02 | 8.81e-01 |
| PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES | 13 | 8.09e-01 | -3.86e-02 | 9.20e-01 |
| CELLULAR SENESCENCE | 143 | 4.26e-01 | -3.86e-02 | 6.99e-01 |
| CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | 12 | 8.17e-01 | -3.85e-02 | 9.25e-01 |
| SELECTIVE AUTOPHAGY | 72 | 5.73e-01 | 3.84e-02 | 7.97e-01 |
| COMMON PATHWAY OF FIBRIN CLOT FORMATION | 11 | 8.26e-01 | -3.83e-02 | 9.28e-01 |
| EPHB MEDIATED FORWARD SIGNALING | 42 | 6.68e-01 | 3.83e-02 | 8.61e-01 |
| RAC3 GTPASE CYCLE | 89 | 5.33e-01 | 3.82e-02 | 7.71e-01 |
| ION TRANSPORT BY P TYPE ATPASES | 49 | 6.45e-01 | -3.81e-02 | 8.47e-01 |
| INTERLEUKIN 20 FAMILY SIGNALING | 14 | 8.05e-01 | 3.81e-02 | 9.19e-01 |
| REGULATION OF FZD BY UBIQUITINATION | 20 | 7.68e-01 | 3.81e-02 | 9.06e-01 |
| LDL CLEARANCE | 16 | 7.92e-01 | -3.80e-02 | 9.16e-01 |
| AUTOPHAGY | 139 | 4.41e-01 | 3.79e-02 | 7.12e-01 |
| TELOMERE C STRAND LAGGING STRAND SYNTHESIS | 33 | 7.07e-01 | 3.79e-02 | 8.83e-01 |
| ADAPTIVE IMMUNE SYSTEM | 603 | 1.16e-01 | 3.76e-02 | 3.57e-01 |
| MICRORNA MIRNA BIOGENESIS | 24 | 7.53e-01 | 3.71e-02 | 9.04e-01 |
| FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS | 82 | 5.62e-01 | -3.71e-02 | 7.86e-01 |
| SIGNALING BY NODAL | 15 | 8.04e-01 | -3.70e-02 | 9.19e-01 |
| SARS COV INFECTIONS | 140 | 4.54e-01 | 3.67e-02 | 7.21e-01 |
| ERBB2 ACTIVATES PTK6 SIGNALING | 11 | 8.35e-01 | 3.62e-02 | 9.33e-01 |
| REGULATED NECROSIS | 46 | 6.72e-01 | 3.62e-02 | 8.65e-01 |
| TRANSCRIPTIONAL REGULATION BY TP53 | 341 | 2.55e-01 | -3.59e-02 | 5.50e-01 |
| SEROTONIN RECEPTORS | 10 | 8.47e-01 | -3.52e-02 | 9.38e-01 |
| FLT3 SIGNALING IN DISEASE | 28 | 7.49e-01 | 3.49e-02 | 9.04e-01 |
| TELOMERE C STRAND SYNTHESIS INITIATION | 13 | 8.28e-01 | 3.48e-02 | 9.30e-01 |
| BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION | 26 | 7.61e-01 | 3.45e-02 | 9.04e-01 |
| HCMV INFECTION | 104 | 5.44e-01 | -3.45e-02 | 7.75e-01 |
| TP53 REGULATES METABOLIC GENES | 85 | 5.83e-01 | 3.44e-02 | 7.98e-01 |
| REGULATION OF TP53 ACTIVITY THROUGH METHYLATION | 18 | 8.01e-01 | -3.44e-02 | 9.17e-01 |
| SUPPRESSION OF PHAGOSOMAL MATURATION | 12 | 8.37e-01 | -3.42e-02 | 9.34e-01 |
| THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS | 27 | 7.59e-01 | 3.42e-02 | 9.04e-01 |
| NEGATIVE REGULATION OF FLT3 | 14 | 8.25e-01 | 3.41e-02 | 9.28e-01 |
| NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | 45 | 6.93e-01 | 3.40e-02 | 8.78e-01 |
| RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE | 23 | 7.78e-01 | 3.39e-02 | 9.10e-01 |
| NEGATIVE REGULATION OF FGFR1 SIGNALING | 26 | 7.65e-01 | -3.39e-02 | 9.05e-01 |
| TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | 31 | 7.45e-01 | 3.38e-02 | 9.03e-01 |
| FANCONI ANEMIA PATHWAY | 36 | 7.27e-01 | -3.36e-02 | 8.92e-01 |
| RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 59 | 6.57e-01 | 3.35e-02 | 8.52e-01 |
| NR1H2 AND NR1H3 MEDIATED SIGNALING | 38 | 7.23e-01 | 3.32e-02 | 8.90e-01 |
| PRE NOTCH EXPRESSION AND PROCESSING | 64 | 6.46e-01 | -3.32e-02 | 8.48e-01 |
| HSF1 DEPENDENT TRANSACTIVATION | 33 | 7.42e-01 | 3.31e-02 | 9.02e-01 |
| N GLYCAN ANTENNAE ELONGATION | 15 | 8.25e-01 | 3.31e-02 | 9.28e-01 |
| POST TRANSLATIONAL PROTEIN MODIFICATION | 1218 | 5.66e-02 | -3.27e-02 | 2.22e-01 |
| PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE | 52 | 6.85e-01 | -3.25e-02 | 8.74e-01 |
| SIGNALING BY NOTCH3 | 48 | 7.02e-01 | -3.20e-02 | 8.80e-01 |
| GABA B RECEPTOR ACTIVATION | 39 | 7.30e-01 | -3.19e-02 | 8.92e-01 |
| CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS | 19 | 8.10e-01 | 3.19e-02 | 9.20e-01 |
| MHC CLASS II ANTIGEN PRESENTATION | 102 | 5.80e-01 | -3.17e-02 | 7.97e-01 |
| RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION | 51 | 6.95e-01 | 3.17e-02 | 8.78e-01 |
| INTERLEUKIN 27 SIGNALING | 10 | 8.62e-01 | -3.17e-02 | 9.44e-01 |
| CHEMOKINE RECEPTORS BIND CHEMOKINES | 17 | 8.22e-01 | -3.15e-02 | 9.27e-01 |
| PLATELET AGGREGATION PLUG FORMATION | 32 | 7.59e-01 | -3.14e-02 | 9.04e-01 |
| NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 20 | 8.09e-01 | -3.13e-02 | 9.20e-01 |
| GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 12 | 8.52e-01 | 3.11e-02 | 9.41e-01 |
| DNA DOUBLE STRAND BREAK RESPONSE | 53 | 6.96e-01 | -3.11e-02 | 8.78e-01 |
| INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC | 186 | 4.66e-01 | -3.10e-02 | 7.24e-01 |
| INTEGRIN SIGNALING | 24 | 7.94e-01 | 3.08e-02 | 9.16e-01 |
| FLT3 SIGNALING | 36 | 7.50e-01 | -3.07e-02 | 9.04e-01 |
| RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY | 24 | 7.95e-01 | -3.07e-02 | 9.16e-01 |
| G ALPHA S SIGNALLING EVENTS | 105 | 5.88e-01 | 3.06e-02 | 8.02e-01 |
| SIGNALING BY FGFR1 | 43 | 7.29e-01 | -3.05e-02 | 8.92e-01 |
| M PHASE | 342 | 3.35e-01 | -3.04e-02 | 6.19e-01 |
| NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 48 | 7.16e-01 | -3.03e-02 | 8.87e-01 |
| CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER | 61 | 6.85e-01 | -3.00e-02 | 8.74e-01 |
| PI 3K CASCADE FGFR4 | 12 | 8.59e-01 | 2.96e-02 | 9.42e-01 |
| RNA POLYMERASE II TRANSCRIPTION TERMINATION | 65 | 6.81e-01 | 2.95e-02 | 8.73e-01 |
| SIGNALING BY ERBB2 IN CANCER | 25 | 8.00e-01 | 2.93e-02 | 9.17e-01 |
| ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | 23 | 8.08e-01 | -2.93e-02 | 9.20e-01 |
| NICOTINATE METABOLISM | 25 | 8.01e-01 | 2.92e-02 | 9.17e-01 |
| REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR | 10 | 8.74e-01 | 2.91e-02 | 9.50e-01 |
| SIGNALING BY ERBB2 ECD MUTANTS | 16 | 8.42e-01 | 2.87e-02 | 9.37e-01 |
| PERK REGULATES GENE EXPRESSION | 28 | 7.93e-01 | -2.87e-02 | 9.16e-01 |
| SIGNALING BY RECEPTOR TYROSINE KINASES | 466 | 2.93e-01 | -2.85e-02 | 5.89e-01 |
| TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | 32 | 7.82e-01 | -2.82e-02 | 9.12e-01 |
| G ALPHA I SIGNALLING EVENTS | 208 | 4.89e-01 | -2.79e-02 | 7.45e-01 |
| CELL CYCLE MITOTIC | 475 | 3.05e-01 | -2.76e-02 | 6.03e-01 |
| REGULATION OF TP53 EXPRESSION AND DEGRADATION | 35 | 7.80e-01 | -2.73e-02 | 9.10e-01 |
| GLUCAGON SIGNALING IN METABOLIC REGULATION | 29 | 8.02e-01 | 2.70e-02 | 9.17e-01 |
| SIGNALING BY BRAF AND RAF FUSIONS | 60 | 7.20e-01 | -2.68e-02 | 8.90e-01 |
| REGULATION OF LIPID METABOLISM BY PPARALPHA | 108 | 6.33e-01 | -2.66e-02 | 8.36e-01 |
| CELLULAR HEXOSE TRANSPORT | 11 | 8.80e-01 | 2.63e-02 | 9.54e-01 |
| SIGNALING BY FLT3 ITD AND TKD MUTANTS | 16 | 8.56e-01 | -2.62e-02 | 9.41e-01 |
| SLC MEDIATED TRANSMEMBRANE TRANSPORT | 192 | 5.35e-01 | 2.60e-02 | 7.71e-01 |
| SURFACTANT METABOLISM | 16 | 8.58e-01 | 2.59e-02 | 9.42e-01 |
| EGFR DOWNREGULATION | 28 | 8.13e-01 | 2.58e-02 | 9.21e-01 |
| TRANSPORT OF SMALL MOLECULES | 581 | 2.90e-01 | 2.58e-02 | 5.85e-01 |
| DUAL INCISION IN GG NER | 40 | 7.78e-01 | -2.58e-02 | 9.10e-01 |
| TRANSLESION SYNTHESIS BY POLK | 17 | 8.55e-01 | 2.57e-02 | 9.41e-01 |
| RNA POLYMERASE II TRANSCRIPTION | 1089 | 1.61e-01 | -2.53e-02 | 4.31e-01 |
| CHOLESTEROL BIOSYNTHESIS | 24 | 8.32e-01 | -2.50e-02 | 9.31e-01 |
| SIGNALING BY GPCR | 499 | 3.43e-01 | -2.49e-02 | 6.27e-01 |
| ONCOGENIC MAPK SIGNALING | 77 | 7.11e-01 | 2.44e-02 | 8.85e-01 |
| GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK | 17 | 8.63e-01 | 2.41e-02 | 9.44e-01 |
| AMINO ACIDS REGULATE MTORC1 | 51 | 7.71e-01 | -2.36e-02 | 9.06e-01 |
| RHOG GTPASE CYCLE | 73 | 7.30e-01 | 2.34e-02 | 8.92e-01 |
| TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | 10 | 8.98e-01 | -2.34e-02 | 9.58e-01 |
| KILLING MECHANISMS | 10 | 8.99e-01 | 2.32e-02 | 9.58e-01 |
| OVARIAN TUMOR DOMAIN PROTEASES | 36 | 8.10e-01 | -2.32e-02 | 9.20e-01 |
| SIGNALING BY TGFB FAMILY MEMBERS | 97 | 6.96e-01 | -2.30e-02 | 8.78e-01 |
| REGULATION OF SIGNALING BY CBL | 22 | 8.52e-01 | 2.29e-02 | 9.41e-01 |
| INTERFERON SIGNALING | 164 | 6.14e-01 | -2.29e-02 | 8.24e-01 |
| CD209 DC SIGN SIGNALING | 18 | 8.69e-01 | 2.25e-02 | 9.48e-01 |
| SEMAPHORIN INTERACTIONS | 64 | 7.56e-01 | -2.25e-02 | 9.04e-01 |
| FORMATION OF RNA POL II ELONGATION COMPLEX | 57 | 7.69e-01 | 2.25e-02 | 9.06e-01 |
| TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | 13 | 8.88e-01 | 2.25e-02 | 9.58e-01 |
| ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS | 22 | 8.55e-01 | -2.25e-02 | 9.41e-01 |
| DOWNREGULATION OF ERBB2 SIGNALING | 28 | 8.39e-01 | 2.21e-02 | 9.36e-01 |
| INTEGRATION OF ENERGY METABOLISM | 98 | 7.06e-01 | -2.21e-02 | 8.83e-01 |
| INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | 13 | 8.91e-01 | 2.19e-02 | 9.58e-01 |
| GLUCONEOGENESIS | 27 | 8.44e-01 | -2.19e-02 | 9.37e-01 |
| MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS | 18 | 8.73e-01 | -2.18e-02 | 9.50e-01 |
| SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | 62 | 7.67e-01 | 2.18e-02 | 9.05e-01 |
| MAPK FAMILY SIGNALING CASCADES | 287 | 5.26e-01 | 2.18e-02 | 7.70e-01 |
| HIV TRANSCRIPTION ELONGATION | 42 | 8.11e-01 | 2.13e-02 | 9.20e-01 |
| MET ACTIVATES PTK2 SIGNALING | 29 | 8.43e-01 | -2.13e-02 | 9.37e-01 |
| CELL CYCLE | 590 | 3.88e-01 | -2.09e-02 | 6.67e-01 |
| CELL CYCLE CHECKPOINTS | 243 | 5.81e-01 | 2.06e-02 | 7.97e-01 |
| MET ACTIVATES RAP1 AND RAC1 | 10 | 9.10e-01 | -2.06e-02 | 9.60e-01 |
| RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION | 23 | 8.65e-01 | 2.05e-02 | 9.45e-01 |
| CARGO CONCENTRATION IN THE ER | 31 | 8.44e-01 | -2.05e-02 | 9.37e-01 |
| VLDLR INTERNALISATION AND DEGRADATION | 12 | 9.02e-01 | 2.04e-02 | 9.58e-01 |
| OXIDATIVE STRESS INDUCED SENESCENCE | 79 | 7.59e-01 | -1.99e-02 | 9.04e-01 |
| NOTCH HLH TRANSCRIPTION PATHWAY | 28 | 8.55e-01 | -1.99e-02 | 9.41e-01 |
| TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS | 28 | 8.56e-01 | 1.98e-02 | 9.41e-01 |
| CYCLIN D ASSOCIATED EVENTS IN G1 | 45 | 8.22e-01 | 1.94e-02 | 9.27e-01 |
| CD28 DEPENDENT PI3K AKT SIGNALING | 21 | 8.78e-01 | -1.94e-02 | 9.53e-01 |
| ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY | 11 | 9.13e-01 | 1.91e-02 | 9.61e-01 |
| TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES | 37 | 8.44e-01 | -1.87e-02 | 9.37e-01 |
| PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE | 19 | 8.88e-01 | 1.86e-02 | 9.58e-01 |
| RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY | 15 | 9.04e-01 | -1.81e-02 | 9.58e-01 |
| APOPTOTIC EXECUTION PHASE | 45 | 8.35e-01 | 1.80e-02 | 9.33e-01 |
| CONSTITUTIVE SIGNALING BY EGFRVIII | 15 | 9.07e-01 | -1.74e-02 | 9.58e-01 |
| PI3K AKT SIGNALING IN CANCER | 88 | 7.78e-01 | -1.74e-02 | 9.10e-01 |
| RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | 28 | 8.74e-01 | -1.73e-02 | 9.50e-01 |
| MEIOTIC RECOMBINATION | 38 | 8.54e-01 | 1.73e-02 | 9.41e-01 |
| PI 3K CASCADE FGFR3 | 13 | 9.15e-01 | 1.71e-02 | 9.61e-01 |
| PI3K EVENTS IN ERBB2 SIGNALING | 15 | 9.11e-01 | -1.67e-02 | 9.60e-01 |
| COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 87 | 7.90e-01 | 1.65e-02 | 9.15e-01 |
| SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | 31 | 8.75e-01 | 1.63e-02 | 9.51e-01 |
| RNA POLYMERASE III CHAIN ELONGATION | 18 | 9.10e-01 | 1.54e-02 | 9.60e-01 |
| DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE | 26 | 8.93e-01 | -1.52e-02 | 9.58e-01 |
| TRANSCRIPTION OF THE HIV GENOME | 67 | 8.32e-01 | 1.50e-02 | 9.31e-01 |
| ESTROGEN DEPENDENT GENE EXPRESSION | 104 | 7.97e-01 | 1.46e-02 | 9.17e-01 |
| GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER | 83 | 8.21e-01 | -1.44e-02 | 9.27e-01 |
| ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | 286 | 6.78e-01 | -1.43e-02 | 8.71e-01 |
| UB SPECIFIC PROCESSING PROTEASES | 167 | 7.54e-01 | 1.41e-02 | 9.04e-01 |
| SIGNALING BY SCF KIT | 41 | 8.78e-01 | 1.38e-02 | 9.53e-01 |
| NEGATIVE REGULATION OF FGFR2 SIGNALING | 27 | 9.01e-01 | -1.38e-02 | 9.58e-01 |
| ER QUALITY CONTROL COMPARTMENT ERQC | 21 | 9.14e-01 | 1.36e-02 | 9.61e-01 |
| RHO GTPASE EFFECTORS | 252 | 7.15e-01 | -1.34e-02 | 8.86e-01 |
| BASE EXCISION REPAIR AP SITE FORMATION | 30 | 9.00e-01 | -1.33e-02 | 9.58e-01 |
| RAF INDEPENDENT MAPK1 3 ACTIVATION | 21 | 9.17e-01 | 1.31e-02 | 9.61e-01 |
| MITOTIC G2 G2 M PHASES | 184 | 7.61e-01 | -1.30e-02 | 9.04e-01 |
| FORMATION OF INCISION COMPLEX IN GG NER | 43 | 8.83e-01 | -1.29e-02 | 9.55e-01 |
| SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL | 10 | 9.43e-01 | 1.29e-02 | 9.76e-01 |
| SIGNALING BY NOTCH1 | 75 | 8.47e-01 | -1.29e-02 | 9.38e-01 |
| MYD88 INDEPENDENT TLR4 CASCADE | 93 | 8.31e-01 | 1.28e-02 | 9.31e-01 |
| IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX | 10 | 9.46e-01 | 1.25e-02 | 9.76e-01 |
| RIPK1 MEDIATED REGULATED NECROSIS | 25 | 9.14e-01 | -1.25e-02 | 9.61e-01 |
| O LINKED GLYCOSYLATION OF MUCINS | 39 | 8.94e-01 | -1.24e-02 | 9.58e-01 |
| CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION | 22 | 9.21e-01 | -1.22e-02 | 9.64e-01 |
| PI 3K CASCADE FGFR2 | 16 | 9.33e-01 | -1.21e-02 | 9.74e-01 |
| SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER | 59 | 8.73e-01 | 1.21e-02 | 9.50e-01 |
| HEMOSTASIS | 473 | 6.57e-01 | 1.20e-02 | 8.52e-01 |
| RNA POLYMERASE III TRANSCRIPTION | 41 | 8.95e-01 | -1.19e-02 | 9.58e-01 |
| TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST | 15 | 9.37e-01 | -1.19e-02 | 9.74e-01 |
| TOLL LIKE RECEPTOR CASCADES | 138 | 8.11e-01 | 1.18e-02 | 9.20e-01 |
| PLATELET SENSITIZATION BY LDL | 15 | 9.37e-01 | -1.18e-02 | 9.74e-01 |
| RHOC GTPASE CYCLE | 73 | 8.62e-01 | -1.18e-02 | 9.44e-01 |
| SCAVENGING OF HEME FROM PLASMA | 10 | 9.49e-01 | -1.17e-02 | 9.76e-01 |
| TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 43 | 8.95e-01 | -1.16e-02 | 9.58e-01 |
| SIGNALING BY FGFR IN DISEASE | 55 | 8.82e-01 | -1.16e-02 | 9.54e-01 |
| GOLGI TO ER RETROGRADE TRANSPORT | 120 | 8.32e-01 | -1.12e-02 | 9.31e-01 |
| SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA | 42 | 9.01e-01 | -1.11e-02 | 9.58e-01 |
| SUMOYLATION OF TRANSCRIPTION COFACTORS | 42 | 9.01e-01 | -1.11e-02 | 9.58e-01 |
| TRANSLESION SYNTHESIS BY POLH | 19 | 9.34e-01 | -1.09e-02 | 9.74e-01 |
| ACTIVATION OF GENE EXPRESSION BY SREBF SREBP | 43 | 9.03e-01 | 1.08e-02 | 9.58e-01 |
| REGULATION OF RUNX1 EXPRESSION AND ACTIVITY | 17 | 9.42e-01 | 1.03e-02 | 9.76e-01 |
| HDACS DEACETYLATE HISTONES | 47 | 9.04e-01 | -1.02e-02 | 9.58e-01 |
| PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | 237 | 7.98e-01 | 9.69e-03 | 9.17e-01 |
| HIV ELONGATION ARREST AND RECOVERY | 32 | 9.27e-01 | 9.35e-03 | 9.70e-01 |
| RAC2 GTPASE CYCLE | 87 | 8.82e-01 | 9.19e-03 | 9.54e-01 |
| ZINC TRANSPORTERS | 16 | 9.51e-01 | -8.93e-03 | 9.76e-01 |
| INTRACELLULAR SIGNALING BY SECOND MESSENGERS | 282 | 8.01e-01 | -8.72e-03 | 9.17e-01 |
| TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE | 63 | 9.05e-01 | -8.72e-03 | 9.58e-01 |
| METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS | 103 | 8.86e-01 | 8.17e-03 | 9.57e-01 |
| POTENTIAL THERAPEUTICS FOR SARS | 77 | 9.03e-01 | -8.06e-03 | 9.58e-01 |
| P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 12 | 9.63e-01 | -7.74e-03 | 9.83e-01 |
| NEGATIVE REGULATION OF FGFR4 SIGNALING | 23 | 9.49e-01 | 7.67e-03 | 9.76e-01 |
| NOD1 2 SIGNALING PATHWAY | 34 | 9.39e-01 | 7.57e-03 | 9.75e-01 |
| POST CHAPERONIN TUBULIN FOLDING PATHWAY | 17 | 9.57e-01 | -7.50e-03 | 9.81e-01 |
| AGGREPHAGY | 35 | 9.39e-01 | 7.42e-03 | 9.75e-01 |
| CONDENSATION OF PROPHASE CHROMOSOMES | 28 | 9.47e-01 | -7.21e-03 | 9.76e-01 |
| COSTIMULATION BY THE CD28 FAMILY | 51 | 9.37e-01 | 6.41e-03 | 9.74e-01 |
| MTOR SIGNALLING | 40 | 9.44e-01 | -6.37e-03 | 9.76e-01 |
| MITOCHONDRIAL CALCIUM ION TRANSPORT | 23 | 9.58e-01 | -6.36e-03 | 9.81e-01 |
| EPH EPHRIN SIGNALING | 92 | 9.17e-01 | -6.31e-03 | 9.61e-01 |
| CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT | 20 | 9.61e-01 | 6.29e-03 | 9.83e-01 |
| PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | 51 | 9.40e-01 | -6.07e-03 | 9.75e-01 |
| INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL | 15 | 9.68e-01 | -5.94e-03 | 9.83e-01 |
| MET PROMOTES CELL MOTILITY | 39 | 9.50e-01 | -5.77e-03 | 9.76e-01 |
| NEPHRIN FAMILY INTERACTIONS | 23 | 9.62e-01 | -5.73e-03 | 9.83e-01 |
| SPRY REGULATION OF FGF SIGNALING | 16 | 9.68e-01 | 5.72e-03 | 9.83e-01 |
| INTEGRIN CELL SURFACE INTERACTIONS | 71 | 9.35e-01 | -5.64e-03 | 9.74e-01 |
| OTHER INTERLEUKIN SIGNALING | 21 | 9.64e-01 | -5.62e-03 | 9.83e-01 |
| TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER | 77 | 9.33e-01 | 5.54e-03 | 9.74e-01 |
| FREE FATTY ACIDS REGULATE INSULIN SECRETION | 10 | 9.76e-01 | -5.49e-03 | 9.85e-01 |
| ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | 33 | 9.58e-01 | 5.33e-03 | 9.81e-01 |
| METABOLISM OF CARBOHYDRATES | 258 | 8.95e-01 | -4.77e-03 | 9.58e-01 |
| METAL ION SLC TRANSPORTERS | 25 | 9.68e-01 | -4.69e-03 | 9.83e-01 |
| LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS | 20 | 9.71e-01 | 4.64e-03 | 9.84e-01 |
| DEUBIQUITINATION | 241 | 9.03e-01 | -4.54e-03 | 9.58e-01 |
| TRNA AMINOACYLATION | 42 | 9.59e-01 | 4.54e-03 | 9.82e-01 |
| PROCESSING OF DNA DOUBLE STRAND BREAK ENDS | 71 | 9.49e-01 | 4.40e-03 | 9.76e-01 |
| ORGANELLE BIOGENESIS AND MAINTENANCE | 284 | 8.99e-01 | -4.40e-03 | 9.58e-01 |
| BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | 76 | 9.49e-01 | -4.21e-03 | 9.76e-01 |
| RNA POLYMERASE III TRANSCRIPTION TERMINATION | 23 | 9.72e-01 | 4.20e-03 | 9.84e-01 |
| ASPARAGINE N LINKED GLYCOSYLATION | 285 | 9.06e-01 | -4.08e-03 | 9.58e-01 |
| AQUAPORIN MEDIATED TRANSPORT | 39 | 9.72e-01 | -3.24e-03 | 9.84e-01 |
| CIRCADIAN CLOCK | 68 | 9.65e-01 | -3.11e-03 | 9.83e-01 |
| REGULATION OF INSULIN SECRETION | 71 | 9.66e-01 | -2.94e-03 | 9.83e-01 |
| CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER | 26 | 9.80e-01 | -2.78e-03 | 9.87e-01 |
| FCERI MEDIATED CA 2 MOBILIZATION | 26 | 9.82e-01 | -2.60e-03 | 9.87e-01 |
| RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER | 28 | 9.81e-01 | 2.54e-03 | 9.87e-01 |
| FORMATION OF TC NER PRE INCISION COMPLEX | 53 | 9.75e-01 | -2.47e-03 | 9.85e-01 |
| BASE EXCISION REPAIR | 57 | 9.75e-01 | -2.44e-03 | 9.85e-01 |
| RHO GTPASES ACTIVATE WASPS AND WAVES | 36 | 9.80e-01 | 2.36e-03 | 9.87e-01 |
| PARASITE INFECTION | 55 | 9.77e-01 | 2.24e-03 | 9.85e-01 |
| NUCLEOTIDE EXCISION REPAIR | 109 | 9.70e-01 | 2.10e-03 | 9.84e-01 |
| NEGATIVE REGULATION OF FGFR3 SIGNALING | 24 | 9.88e-01 | 1.81e-03 | 9.92e-01 |
| DEPOLYMERISATION OF THE NUCLEAR LAMINA | 13 | 9.93e-01 | -1.33e-03 | 9.97e-01 |
| METABOLISM OF PORPHYRINS | 19 | 9.95e-01 | -8.97e-04 | 9.97e-01 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 | 25 | 9.97e-01 | -5.04e-04 | 9.98e-01 |
| DNA DAMAGE BYPASS | 47 | 9.98e-01 | -1.93e-04 | 9.99e-01 |
| TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | 86 | 9.99e-01 | 7.79e-05 | 9.99e-01 |
Detailed Gene set reports
EUKARYOTIC TRANSLATION ELONGATION
| set | EUKARYOTIC TRANSLATION ELONGATION |
| setSize | 87 |
| pANOVA | 5.04e-34 |
| s.dist | 0.753 |
| p.adjustANOVA | 5.94e-31 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Rps29 | 8325 |
| Rpl39 | 8217 |
| Rps21 | 8165 |
| Rpl3 | 8059 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Rps28 | 7899 |
| Rpl38 | 7881 |
| Rps19 | 7880 |
| Rpsa | 7818 |
| Rpl35 | 7727 |
| Rplp2 | 7724 |
| Rpl36 | 7707 |
| Rplp1 | 7699 |
| Rps27a | 7650 |
| Rps9 | 7591 |
| Rps3 | 7581 |
| Rpl13a | 7538 |
| Fau | 7502 |
| Rps6 | 7496 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Rps29 | 8325 |
| Rpl39 | 8217 |
| Rps21 | 8165 |
| Rpl3 | 8059 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Rps28 | 7899 |
| Rpl38 | 7881 |
| Rps19 | 7880 |
| Rpsa | 7818 |
| Rpl35 | 7727 |
| Rplp2 | 7724 |
| Rpl36 | 7707 |
| Rplp1 | 7699 |
| Rps27a | 7650 |
| Rps9 | 7591 |
| Rps3 | 7581 |
| Rpl13a | 7538 |
| Fau | 7502 |
| Rps6 | 7496 |
| Rpl8 | 7495 |
| Rps3a1 | 7466 |
| Rpl22l1 | 7456 |
| Rps5 | 7446 |
| Rps8 | 7442 |
| Rpl37a | 7406 |
| Uba52 | 7390 |
| Rpl27a | 7368 |
| Rps10 | 7263 |
| Rpl18a | 7262 |
| Rps12 | 7244 |
| Rpl13 | 7240 |
| Rps24 | 7234 |
| Rpl9 | 7223 |
| Rps14 | 7194 |
| Rps16 | 7180 |
| Rps13 | 7176 |
| Rps23 | 7139 |
| Eef1d | 7127 |
| Rpl36al | 7116 |
| Rpl34 | 7060 |
| Rpl27 | 7054 |
| Rps15 | 7047 |
| Rps27l | 6994 |
| Eef1b2 | 6956 |
| Rpl23 | 6935 |
| Rpl19 | 6905 |
| Rpl37 | 6889 |
| Rpl32 | 6870 |
| Rpl18 | 6859 |
| Rpl31 | 6770 |
| Rps17 | 6719 |
| Rpl14 | 6633 |
| Rpl23a | 6576 |
| Rps4x | 6516 |
| Rpl35a | 6487 |
| Rps15a | 6468 |
| Rpl21 | 6433 |
| Rplp0 | 6389 |
| Rpl36a | 6363 |
| Rpl17 | 6354 |
| Rps25 | 6317 |
| Eef1a1 | 6294 |
| Rpl30 | 6288 |
| Rpl4 | 6203 |
| Rpl7 | 6140 |
| Rpl10a | 6104 |
| Rpl24 | 5910 |
| Rpl10 | 5873 |
| Rps11 | 5845 |
| Rpl5 | 5817 |
| Rpl11 | 5763 |
| Rps26 | 5705 |
| Eef1g | 5693 |
| Rpl22 | 5587 |
| Rpl15 | 5502 |
| Rpl26 | 5476 |
| Rpl12 | 4905 |
| Rpl29 | 4830 |
| Eef2 | 4634 |
| Rpl6 | 4589 |
| Rps18 | 4496 |
| Rpl7a | 4328 |
| Rpl28 | 4170 |
| Rps7 | 3275 |
| Rps2 | 2143 |
| Eef1a2 | -4833 |
SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE
| set | SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE |
| setSize | 106 |
| pANOVA | 4.1e-33 |
| s.dist | 0.673 |
| p.adjustANOVA | 2.41e-30 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Rps29 | 8325 |
| Rpl39 | 8217 |
| Rps21 | 8165 |
| Sec61g | 8104 |
| Rpl3 | 8059 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Rps28 | 7899 |
| Rpl38 | 7881 |
| Rps19 | 7880 |
| Ssr3 | 7840 |
| Rpsa | 7818 |
| Rpl35 | 7727 |
| Rplp2 | 7724 |
| Rpl36 | 7707 |
| Rplp1 | 7699 |
| Spcs1 | 7680 |
| Rps27a | 7650 |
| Sec61b | 7616 |
| Rps9 | 7591 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Rps29 | 8325 |
| Rpl39 | 8217 |
| Rps21 | 8165 |
| Sec61g | 8104 |
| Rpl3 | 8059 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Rps28 | 7899 |
| Rpl38 | 7881 |
| Rps19 | 7880 |
| Ssr3 | 7840 |
| Rpsa | 7818 |
| Rpl35 | 7727 |
| Rplp2 | 7724 |
| Rpl36 | 7707 |
| Rplp1 | 7699 |
| Spcs1 | 7680 |
| Rps27a | 7650 |
| Sec61b | 7616 |
| Rps9 | 7591 |
| Rps3 | 7581 |
| Rpl13a | 7538 |
| Fau | 7502 |
| Rps6 | 7496 |
| Rpl8 | 7495 |
| Rps3a1 | 7466 |
| Rpl22l1 | 7456 |
| Rps5 | 7446 |
| Rps8 | 7442 |
| Rpl37a | 7406 |
| Uba52 | 7390 |
| Rpl27a | 7368 |
| Rps10 | 7263 |
| Rpl18a | 7262 |
| Rps12 | 7244 |
| Rpl13 | 7240 |
| Rps24 | 7234 |
| Rpl9 | 7223 |
| Rps14 | 7194 |
| Rps16 | 7180 |
| Rps13 | 7176 |
| Rps23 | 7139 |
| Rpl36al | 7116 |
| Rpl34 | 7060 |
| Rpl27 | 7054 |
| Rps15 | 7047 |
| Rps27l | 6994 |
| Rpl23 | 6935 |
| Rpl19 | 6905 |
| Rpl37 | 6889 |
| Rpl32 | 6870 |
| Rpl18 | 6859 |
| Tram1 | 6780 |
| Rpl31 | 6770 |
| Rps17 | 6719 |
| Rpl14 | 6633 |
| Rpl23a | 6576 |
| Ssr4 | 6529 |
| Rps4x | 6516 |
| Rpl35a | 6487 |
| Rps15a | 6468 |
| Rpl21 | 6433 |
| Rplp0 | 6389 |
| Rpl36a | 6363 |
| Rpl17 | 6354 |
| Rps25 | 6317 |
| Rpl30 | 6288 |
| Rpl4 | 6203 |
| Rpl7 | 6140 |
| Rpl10a | 6104 |
| Srp19 | 5926 |
| Rpl24 | 5910 |
| Rpl10 | 5873 |
| Rps11 | 5845 |
| Rpl5 | 5817 |
| Rpl11 | 5763 |
| Rps26 | 5705 |
| Rpl22 | 5587 |
| Rpn2 | 5569 |
| Rpl15 | 5502 |
| Rpl26 | 5476 |
| Sec11c | 5451 |
| Spcs2 | 4943 |
| Rpl12 | 4905 |
| Ssr2 | 4846 |
| Rpl29 | 4830 |
| Rpl6 | 4589 |
| Rps18 | 4496 |
| Rpl7a | 4328 |
| Srp9 | 4193 |
| Rpl28 | 4170 |
| Rpn1 | 3420 |
| Rps7 | 3275 |
| Sec11a | 3016 |
| Ddost | 2887 |
| Srp14 | 2676 |
| Srp54a | 2547 |
| Rps2 | 2143 |
| Sec61a1 | 507 |
| Srp68 | 157 |
| Srpr | 63 |
| Spcs3 | -1014 |
| Ssr1 | -1076 |
| Srp72 | -1847 |
| Srprb | -3751 |
| Sec61a2 | -5451 |
RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY
| set | RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY |
| setSize | 95 |
| pANOVA | 7.03e-28 |
| s.dist | 0.649 |
| p.adjustANOVA | 1.66e-25 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Rps29 | 8325 |
| Rpl39 | 8217 |
| Rps21 | 8165 |
| Rpl3 | 8059 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Rps28 | 7899 |
| Rpl38 | 7881 |
| Rps19 | 7880 |
| Rpsa | 7818 |
| Rpl35 | 7727 |
| Rplp2 | 7724 |
| Rpl36 | 7707 |
| Rplp1 | 7699 |
| Rps27a | 7650 |
| Rps9 | 7591 |
| Rps3 | 7581 |
| Rpl13a | 7538 |
| Fau | 7502 |
| Rps6 | 7496 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Rps29 | 8325 |
| Rpl39 | 8217 |
| Rps21 | 8165 |
| Rpl3 | 8059 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Rps28 | 7899 |
| Rpl38 | 7881 |
| Rps19 | 7880 |
| Rpsa | 7818 |
| Rpl35 | 7727 |
| Rplp2 | 7724 |
| Rpl36 | 7707 |
| Rplp1 | 7699 |
| Rps27a | 7650 |
| Rps9 | 7591 |
| Rps3 | 7581 |
| Rpl13a | 7538 |
| Fau | 7502 |
| Rps6 | 7496 |
| Rpl8 | 7495 |
| Rps3a1 | 7466 |
| Rpl22l1 | 7456 |
| Rps5 | 7446 |
| Rps8 | 7442 |
| Rpl37a | 7406 |
| Uba52 | 7390 |
| Rpl27a | 7368 |
| Rps10 | 7263 |
| Rpl18a | 7262 |
| Rps12 | 7244 |
| Rpl13 | 7240 |
| Rps24 | 7234 |
| Rpl9 | 7223 |
| Rps14 | 7194 |
| Rps16 | 7180 |
| Rps13 | 7176 |
| Rps23 | 7139 |
| Rpl36al | 7116 |
| Rpl34 | 7060 |
| Rpl27 | 7054 |
| Rps15 | 7047 |
| Rps27l | 6994 |
| Rpl23 | 6935 |
| Rpl19 | 6905 |
| Rpl37 | 6889 |
| Rpl32 | 6870 |
| Rpl18 | 6859 |
| Rpl31 | 6770 |
| Rps17 | 6719 |
| Rpl14 | 6633 |
| Rpl23a | 6576 |
| Rps4x | 6516 |
| Rpl35a | 6487 |
| Rps15a | 6468 |
| Rpl21 | 6433 |
| Rplp0 | 6389 |
| Rpl36a | 6363 |
| Rpl17 | 6354 |
| Rps25 | 6317 |
| Rpl30 | 6288 |
| Rpl4 | 6203 |
| Rpl7 | 6140 |
| Rpl10a | 6104 |
| Rpl24 | 5910 |
| Rpl10 | 5873 |
| Rps11 | 5845 |
| Rpl5 | 5817 |
| Rpl11 | 5763 |
| Rps26 | 5705 |
| Rpl22 | 5587 |
| Rpl15 | 5502 |
| Rpl26 | 5476 |
| Rpl12 | 4905 |
| Rpl29 | 4830 |
| Rpl6 | 4589 |
| Rps18 | 4496 |
| Rpl7a | 4328 |
| Rpl28 | 4170 |
| Ddit3 | 4082 |
| Eif2s3x | 3871 |
| Eif2s2 | 3839 |
| Rps7 | 3275 |
| Trib3 | 2830 |
| Impact | 2367 |
| Rps2 | 2143 |
| Gcn1 | 1962 |
| Atf3 | 1512 |
| Atf4 | -536 |
| Cebpg | -983 |
| Eif2s1 | -2149 |
| Cebpb | -2830 |
| Atf2 | -6236 |
| Asns | -6356 |
| Eif2ak4 | -7339 |
EUKARYOTIC TRANSLATION INITIATION
| set | EUKARYOTIC TRANSLATION INITIATION |
| setSize | 114 |
| pANOVA | 5.6e-31 |
| s.dist | 0.627 |
| p.adjustANOVA | 1.65e-28 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Rps29 | 8325 |
| Rpl39 | 8217 |
| Eif3f | 8193 |
| Rps21 | 8165 |
| Rpl3 | 8059 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Rps28 | 7899 |
| Rpl38 | 7881 |
| Rps19 | 7880 |
| Rpsa | 7818 |
| Eif4a1 | 7791 |
| Rpl35 | 7727 |
| Rplp2 | 7724 |
| Rpl36 | 7707 |
| Rplp1 | 7699 |
| Rps27a | 7650 |
| Eif3j2 | 7628 |
| Rps9 | 7591 |
| Rps3 | 7581 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Rps29 | 8325 |
| Rpl39 | 8217 |
| Eif3f | 8193 |
| Rps21 | 8165 |
| Rpl3 | 8059 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Rps28 | 7899 |
| Rpl38 | 7881 |
| Rps19 | 7880 |
| Rpsa | 7818 |
| Eif4a1 | 7791 |
| Rpl35 | 7727 |
| Rplp2 | 7724 |
| Rpl36 | 7707 |
| Rplp1 | 7699 |
| Rps27a | 7650 |
| Eif3j2 | 7628 |
| Rps9 | 7591 |
| Rps3 | 7581 |
| Rpl13a | 7538 |
| Fau | 7502 |
| Rps6 | 7496 |
| Rpl8 | 7495 |
| Rps3a1 | 7466 |
| Rpl22l1 | 7456 |
| Rps5 | 7446 |
| Rps8 | 7442 |
| Rpl37a | 7406 |
| Uba52 | 7390 |
| Rpl27a | 7368 |
| Rps10 | 7263 |
| Rpl18a | 7262 |
| Eif3b | 7245 |
| Rps12 | 7244 |
| Rpl13 | 7240 |
| Rps24 | 7234 |
| Rpl9 | 7223 |
| Rps14 | 7194 |
| Rps16 | 7180 |
| Rps13 | 7176 |
| Rps23 | 7139 |
| Rpl36al | 7116 |
| Rpl34 | 7060 |
| Rpl27 | 7054 |
| Rps15 | 7047 |
| Rps27l | 6994 |
| Rpl23 | 6935 |
| Rpl19 | 6905 |
| Rpl37 | 6889 |
| Rpl32 | 6870 |
| Rpl18 | 6859 |
| Rpl31 | 6770 |
| Rps17 | 6719 |
| Eif3l | 6652 |
| Rpl14 | 6633 |
| Rpl23a | 6576 |
| Rps4x | 6516 |
| Rpl35a | 6487 |
| Eif2b5 | 6486 |
| Rps15a | 6468 |
| Rpl21 | 6433 |
| Rplp0 | 6389 |
| Rpl36a | 6363 |
| Rpl17 | 6354 |
| Rps25 | 6317 |
| Rpl30 | 6288 |
| Rpl4 | 6203 |
| Rpl7 | 6140 |
| Eif3m | 6107 |
| Rpl10a | 6104 |
| Rpl24 | 5910 |
| Rpl10 | 5873 |
| Rps11 | 5845 |
| Rpl5 | 5817 |
| Eif2b4 | 5807 |
| Rpl11 | 5763 |
| Eif3e | 5752 |
| Rps26 | 5705 |
| Rpl22 | 5587 |
| Eif3d | 5586 |
| Pabpc1 | 5562 |
| Rpl15 | 5502 |
| Rpl26 | 5476 |
| Eif3i | 5418 |
| Eif3k | 5051 |
| Rpl12 | 4905 |
| Rpl29 | 4830 |
| Rpl6 | 4589 |
| Eif4ebp1 | 4505 |
| Rps18 | 4496 |
| Rpl7a | 4328 |
| Eif3h | 4201 |
| Rpl28 | 4170 |
| Eif2s3x | 3871 |
| Eif2s2 | 3839 |
| Eif4e | 3721 |
| Rps7 | 3275 |
| Rps2 | 2143 |
| Eif3g | 2061 |
| Eif2b2 | 1157 |
| Eif5b | 996 |
| Eif3j1 | 483 |
| Eif2b3 | 454 |
| Eif3c | 409 |
| Eif4h | -21 |
| Eif4a2 | -2044 |
| Eif2s1 | -2149 |
| Eif4g1 | -2240 |
| Eif4b | -2682 |
| Eif5 | -3724 |
| Eif1ax | -5164 |
| Eif2b1 | -5626 |
| Eif3a | -5816 |
REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO
| set | REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO |
| setSize | 10 |
| pANOVA | 0.000604 |
| s.dist | -0.626 |
| p.adjustANOVA | 0.00666 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Nell2 | -7516 |
| Slit3 | -7300 |
| Slit1 | -6972 |
| Robo3 | -5970 |
| Robo2 | -5165 |
| Ntn1 | -4877 |
| Slit2 | -4682 |
| Src | -4513 |
| Robo1 | -3170 |
| Dcc | -1809 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Nell2 | -7516 |
| Slit3 | -7300 |
| Slit1 | -6972 |
| Robo3 | -5970 |
| Robo2 | -5165 |
| Ntn1 | -4877 |
| Slit2 | -4682 |
| Src | -4513 |
| Robo1 | -3170 |
| Dcc | -1809 |
YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION
| set | YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION |
| setSize | 11 |
| pANOVA | 0.000432 |
| s.dist | 0.613 |
| p.adjustANOVA | 0.00504 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Yap1 | 8610 |
| Tead2 | 8388 |
| Ccn2 | 8180 |
| Tead1 | 7665 |
| Hipk2 | 6424 |
| Wwtr1 | 6388 |
| Kat2b | 3883 |
| Nppa | 3407 |
| Runx2 | 3069 |
| Tead3 | 2146 |
| Hipk1 | 1120 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Yap1 | 8610 |
| Tead2 | 8388 |
| Ccn2 | 8180 |
| Tead1 | 7665 |
| Hipk2 | 6424 |
| Wwtr1 | 6388 |
| Kat2b | 3883 |
| Nppa | 3407 |
| Runx2 | 3069 |
| Tead3 | 2146 |
| Hipk1 | 1120 |
ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S
| set | ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S |
| setSize | 59 |
| pANOVA | 9.2e-15 |
| s.dist | 0.583 |
| p.adjustANOVA | 7.74e-13 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Rps29 | 8325 |
| Eif3f | 8193 |
| Rps21 | 8165 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Rps28 | 7899 |
| Rps19 | 7880 |
| Rpsa | 7818 |
| Eif4a1 | 7791 |
| Rps27a | 7650 |
| Eif3j2 | 7628 |
| Rps9 | 7591 |
| Rps3 | 7581 |
| Fau | 7502 |
| Rps6 | 7496 |
| Rps3a1 | 7466 |
| Rps5 | 7446 |
| Rps8 | 7442 |
| Rps10 | 7263 |
| Eif3b | 7245 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Rps29 | 8325 |
| Eif3f | 8193 |
| Rps21 | 8165 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Rps28 | 7899 |
| Rps19 | 7880 |
| Rpsa | 7818 |
| Eif4a1 | 7791 |
| Rps27a | 7650 |
| Eif3j2 | 7628 |
| Rps9 | 7591 |
| Rps3 | 7581 |
| Fau | 7502 |
| Rps6 | 7496 |
| Rps3a1 | 7466 |
| Rps5 | 7446 |
| Rps8 | 7442 |
| Rps10 | 7263 |
| Eif3b | 7245 |
| Rps12 | 7244 |
| Rps24 | 7234 |
| Rps14 | 7194 |
| Rps16 | 7180 |
| Rps13 | 7176 |
| Rps23 | 7139 |
| Rps15 | 7047 |
| Rps27l | 6994 |
| Rps17 | 6719 |
| Eif3l | 6652 |
| Rps4x | 6516 |
| Rps15a | 6468 |
| Rps25 | 6317 |
| Eif3m | 6107 |
| Rps11 | 5845 |
| Eif3e | 5752 |
| Rps26 | 5705 |
| Eif3d | 5586 |
| Pabpc1 | 5562 |
| Eif3i | 5418 |
| Eif3k | 5051 |
| Eif4ebp1 | 4505 |
| Rps18 | 4496 |
| Eif3h | 4201 |
| Eif2s3x | 3871 |
| Eif2s2 | 3839 |
| Eif4e | 3721 |
| Rps7 | 3275 |
| Rps2 | 2143 |
| Eif3g | 2061 |
| Eif3j1 | 483 |
| Eif3c | 409 |
| Eif4h | -21 |
| Eif4a2 | -2044 |
| Eif2s1 | -2149 |
| Eif4g1 | -2240 |
| Eif4b | -2682 |
| Eif1ax | -5164 |
| Eif3a | -5816 |
SELENOAMINO ACID METABOLISM
| set | SELENOAMINO ACID METABOLISM |
| setSize | 109 |
| pANOVA | 2.15e-25 |
| s.dist | 0.577 |
| p.adjustANOVA | 4.22e-23 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Ahcy | 8530 |
| Rps29 | 8325 |
| Rpl39 | 8217 |
| Rps21 | 8165 |
| Rpl3 | 8059 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Aimp2 | 7927 |
| Rps28 | 7899 |
| Rpl38 | 7881 |
| Rps19 | 7880 |
| Rpsa | 7818 |
| Rpl35 | 7727 |
| Rplp2 | 7724 |
| Rpl36 | 7707 |
| Rplp1 | 7699 |
| Rps27a | 7650 |
| Rps9 | 7591 |
| Rps3 | 7581 |
| Rpl13a | 7538 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Ahcy | 8530 |
| Rps29 | 8325 |
| Rpl39 | 8217 |
| Rps21 | 8165 |
| Rpl3 | 8059 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Aimp2 | 7927 |
| Rps28 | 7899 |
| Rpl38 | 7881 |
| Rps19 | 7880 |
| Rpsa | 7818 |
| Rpl35 | 7727 |
| Rplp2 | 7724 |
| Rpl36 | 7707 |
| Rplp1 | 7699 |
| Rps27a | 7650 |
| Rps9 | 7591 |
| Rps3 | 7581 |
| Rpl13a | 7538 |
| Fau | 7502 |
| Rps6 | 7496 |
| Rpl8 | 7495 |
| Rps3a1 | 7466 |
| Rpl22l1 | 7456 |
| Rps5 | 7446 |
| Rps8 | 7442 |
| Rpl37a | 7406 |
| Uba52 | 7390 |
| Rpl27a | 7368 |
| Rps10 | 7263 |
| Rpl18a | 7262 |
| Qars | 7261 |
| Rps12 | 7244 |
| Rpl13 | 7240 |
| Rps24 | 7234 |
| Cth | 7224 |
| Rpl9 | 7223 |
| Nnmt | 7217 |
| Rps14 | 7194 |
| Rps16 | 7180 |
| Rps13 | 7176 |
| Rps23 | 7139 |
| Rpl36al | 7116 |
| Rpl34 | 7060 |
| Rpl27 | 7054 |
| Rps15 | 7047 |
| Rps27l | 6994 |
| Rpl23 | 6935 |
| Rpl19 | 6905 |
| Rpl37 | 6889 |
| Rpl32 | 6870 |
| Rpl18 | 6859 |
| Rpl31 | 6770 |
| Rps17 | 6719 |
| Rpl14 | 6633 |
| Rpl23a | 6576 |
| Rps4x | 6516 |
| Rpl35a | 6487 |
| Rps15a | 6468 |
| Rpl21 | 6433 |
| Rplp0 | 6389 |
| Rpl36a | 6363 |
| Rpl17 | 6354 |
| Rps25 | 6317 |
| Rpl30 | 6288 |
| Aimp1 | 6270 |
| Rpl4 | 6203 |
| Rpl7 | 6140 |
| Rpl10a | 6104 |
| Pstk | 6052 |
| Rpl24 | 5910 |
| Rpl10 | 5873 |
| Rps11 | 5845 |
| Rpl5 | 5817 |
| Rpl11 | 5763 |
| Rps26 | 5705 |
| Eef1e1 | 5676 |
| Rpl22 | 5587 |
| Rpl15 | 5502 |
| Rpl26 | 5476 |
| Sephs2 | 4917 |
| Rpl12 | 4905 |
| Rpl29 | 4830 |
| Rpl6 | 4589 |
| Rps18 | 4496 |
| Rpl7a | 4328 |
| Rpl28 | 4170 |
| Rps7 | 3275 |
| Papss2 | 2966 |
| Papss1 | 2389 |
| Rps2 | 2143 |
| Gsr | 1994 |
| Cbs | 1303 |
| Kars | 1027 |
| Eefsec | 738 |
| Scly | -2846 |
| Hnmt | -2920 |
| Mars1 | -3089 |
| Rars | -3143 |
| Gnmt | -3939 |
| Eprs | -4256 |
| Lars | -4585 |
| Txnrd1 | -5189 |
| Dars | -5550 |
| Sepsecs | -6753 |
| Secisbp2 | -7375 |
| Iars | -7715 |
| Sars | -8043 |
ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS
| set | ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS |
| setSize | 10 |
| pANOVA | 0.00245 |
| s.dist | -0.553 |
| p.adjustANOVA | 0.0209 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Fos | -7886 |
| Jun | -7598 |
| Mapk8 | -7465 |
| Atf2 | -6236 |
| Mapk10 | -6198 |
| Mapk9 | -5765 |
| Mapk11 | -4774 |
| Mapk1 | -2436 |
| Mapk14 | -1646 |
| Mapk3 | 4265 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Fos | -7886 |
| Jun | -7598 |
| Mapk8 | -7465 |
| Atf2 | -6236 |
| Mapk10 | -6198 |
| Mapk9 | -5765 |
| Mapk11 | -4774 |
| Mapk1 | -2436 |
| Mapk14 | -1646 |
| Mapk3 | 4265 |
FORMATION OF ATP BY CHEMIOSMOTIC COUPLING
| set | FORMATION OF ATP BY CHEMIOSMOTIC COUPLING |
| setSize | 18 |
| pANOVA | 7.61e-05 |
| s.dist | 0.539 |
| p.adjustANOVA | 0.00134 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Atp5g2 | 8457 |
| mt-Atp8 | 8090 |
| Atp5e | 7419 |
| Atp5k | 7191 |
| Atp5l | 6507 |
| mt-Atp6 | 6401 |
| Atp5h | 6283 |
| Atp5g3 | 6018 |
| Atp5d | 5331 |
| Atp5j2 | 3902 |
| Atp5j | 3861 |
| Atp5c1 | 3539 |
| Atp5a1 | 3507 |
| Atp5g1 | 3376 |
| Atp5b | 2773 |
| Dmac2l | 1976 |
| Atp5pb | 826 |
| Atp5o | 98 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Atp5g2 | 8457 |
| mt-Atp8 | 8090 |
| Atp5e | 7419 |
| Atp5k | 7191 |
| Atp5l | 6507 |
| mt-Atp6 | 6401 |
| Atp5h | 6283 |
| Atp5g3 | 6018 |
| Atp5d | 5331 |
| Atp5j2 | 3902 |
| Atp5j | 3861 |
| Atp5c1 | 3539 |
| Atp5a1 | 3507 |
| Atp5g1 | 3376 |
| Atp5b | 2773 |
| Dmac2l | 1976 |
| Atp5pb | 826 |
| Atp5o | 98 |
NONSENSE MEDIATED DECAY NMD
| set | NONSENSE MEDIATED DECAY NMD |
| setSize | 109 |
| pANOVA | 2.99e-21 |
| s.dist | 0.524 |
| p.adjustANOVA | 3.91e-19 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Rps29 | 8325 |
| Rpl39 | 8217 |
| Rps21 | 8165 |
| Rpl3 | 8059 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Rps28 | 7899 |
| Rpl38 | 7881 |
| Rps19 | 7880 |
| Rpsa | 7818 |
| Magoh | 7812 |
| Rpl35 | 7727 |
| Rplp2 | 7724 |
| Rpl36 | 7707 |
| Rplp1 | 7699 |
| Rps27a | 7650 |
| Rps9 | 7591 |
| Rps3 | 7581 |
| Rpl13a | 7538 |
| Fau | 7502 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Rps29 | 8325 |
| Rpl39 | 8217 |
| Rps21 | 8165 |
| Rpl3 | 8059 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Rps28 | 7899 |
| Rpl38 | 7881 |
| Rps19 | 7880 |
| Rpsa | 7818 |
| Magoh | 7812 |
| Rpl35 | 7727 |
| Rplp2 | 7724 |
| Rpl36 | 7707 |
| Rplp1 | 7699 |
| Rps27a | 7650 |
| Rps9 | 7591 |
| Rps3 | 7581 |
| Rpl13a | 7538 |
| Fau | 7502 |
| Rps6 | 7496 |
| Rpl8 | 7495 |
| Rps3a1 | 7466 |
| Rpl22l1 | 7456 |
| Rps5 | 7446 |
| Rps8 | 7442 |
| Rpl37a | 7406 |
| Uba52 | 7390 |
| Rpl27a | 7368 |
| Rps10 | 7263 |
| Rpl18a | 7262 |
| Rps12 | 7244 |
| Rpl13 | 7240 |
| Rps24 | 7234 |
| Rpl9 | 7223 |
| Rps14 | 7194 |
| Rps16 | 7180 |
| Rps13 | 7176 |
| Rps23 | 7139 |
| Rpl36al | 7116 |
| Rpl34 | 7060 |
| Rpl27 | 7054 |
| Rps15 | 7047 |
| Rps27l | 6994 |
| Rpl23 | 6935 |
| Rpl19 | 6905 |
| Rpl37 | 6889 |
| Rpl32 | 6870 |
| Rpl18 | 6859 |
| Rpl31 | 6770 |
| Rps17 | 6719 |
| Ncbp1 | 6701 |
| Rpl14 | 6633 |
| Rpl23a | 6576 |
| Rps4x | 6516 |
| Rpl35a | 6487 |
| Rps15a | 6468 |
| Rpl21 | 6433 |
| Rplp0 | 6389 |
| Rpl36a | 6363 |
| Rpl17 | 6354 |
| Rps25 | 6317 |
| Rpl30 | 6288 |
| Rbm8a | 6262 |
| Rpl4 | 6203 |
| Rpl7 | 6140 |
| Rpl10a | 6104 |
| Rpl24 | 5910 |
| Rpl10 | 5873 |
| Rps11 | 5845 |
| Rpl5 | 5817 |
| Rpl11 | 5763 |
| Rps26 | 5705 |
| Rpl22 | 5587 |
| Pabpc1 | 5562 |
| Rpl15 | 5502 |
| Rpl26 | 5476 |
| Pnrc2 | 5214 |
| Rpl12 | 4905 |
| Rpl29 | 4830 |
| Rpl6 | 4589 |
| Rps18 | 4496 |
| Rpl7a | 4328 |
| Rpl28 | 4170 |
| Eif4a3 | 3538 |
| Rps7 | 3275 |
| Rps2 | 2143 |
| Smg1 | 277 |
| Upf2 | -51 |
| Smg7 | -287 |
| Upf3b | -603 |
| Upf3a | -1445 |
| Rnps1 | -2027 |
| Eif4g1 | -2240 |
| Gspt1 | -2349 |
| Ppp2ca | -2719 |
| Upf1 | -2741 |
| Smg5 | -3899 |
| Casc3 | -4016 |
| Ppp2r1a | -4370 |
| Gspt2 | -4765 |
| Dcp1a | -5084 |
| Smg8 | -5251 |
| Ncbp2 | -5269 |
| Ppp2r2a | -5293 |
| Etf1 | -5342 |
| Smg6 | -6631 |
| Magohb | -6733 |
| Smg9 | -6776 |
COMPLEX I BIOGENESIS
| set | COMPLEX I BIOGENESIS |
| setSize | 56 |
| pANOVA | 1.96e-11 |
| s.dist | 0.518 |
| p.adjustANOVA | 1.21e-09 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Ndufa2 | 7963 |
| mt-Nd3 | 7923 |
| Ndufb2 | 7696 |
| mt-Nd6 | 7500 |
| Ndufaf5 | 7376 |
| Ndufa1 | 7278 |
| Ndufs3 | 7185 |
| mt-Nd5 | 7002 |
| Ndufaf1 | 6861 |
| Ndufb10 | 6726 |
| Timmdc1 | 6716 |
| mt-Nd4 | 6667 |
| Ndufb11 | 6666 |
| mt-Nd2 | 6657 |
| Ndufaf7 | 6650 |
| Ndufv1 | 6606 |
| Ndufb9 | 6566 |
| Ndufb1 | 6523 |
| Ecsit | 6255 |
| Ndufs6 | 6240 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Ndufa2 | 7963 |
| mt-Nd3 | 7923 |
| Ndufb2 | 7696 |
| mt-Nd6 | 7500 |
| Ndufaf5 | 7376 |
| Ndufa1 | 7278 |
| Ndufs3 | 7185 |
| mt-Nd5 | 7002 |
| Ndufaf1 | 6861 |
| Ndufb10 | 6726 |
| Timmdc1 | 6716 |
| mt-Nd4 | 6667 |
| Ndufb11 | 6666 |
| mt-Nd2 | 6657 |
| Ndufaf7 | 6650 |
| Ndufv1 | 6606 |
| Ndufb9 | 6566 |
| Ndufb1 | 6523 |
| Ecsit | 6255 |
| Ndufs6 | 6240 |
| mt-Nd1 | 6157 |
| Ndufa3 | 6040 |
| Ndufaf6 | 6023 |
| Ndufb8 | 6022 |
| Ndufa7 | 5942 |
| Ndufc2 | 5918 |
| Ndufc1 | 5901 |
| Ndufb4 | 5866 |
| Ndufa6 | 5748 |
| Ndufab1 | 5531 |
| Ndufs5 | 5396 |
| Ndufa13 | 5381 |
| Ndufa11 | 5153 |
| Ndufa5 | 5144 |
| Ndufb7 | 4964 |
| Ndufb6 | 4790 |
| Ndufb5 | 4719 |
| Ndufaf3 | 4397 |
| Ndufs7 | 4138 |
| Nubpl | 3930 |
| Ndufs2 | 3779 |
| Ndufa12 | 3663 |
| Ndufs4 | 3561 |
| Ndufa8 | 3300 |
| Ndufv3 | 3082 |
| Ndufs8 | 3026 |
| Ndufv2 | 2411 |
| Ndufb3 | 2058 |
| Ndufaf2 | 1345 |
| Ndufa9 | 886 |
| Acad9 | -240 |
| Tmem126b | -1183 |
| Ndufaf4 | -2005 |
| Ndufa10 | -3073 |
| Ndufs1 | -3913 |
| Tmem186 | -7055 |
CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS
| set | CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS |
| setSize | 12 |
| pANOVA | 0.00197 |
| s.dist | -0.516 |
| p.adjustANOVA | 0.0175 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Grm2 | -8216 |
| Gabbr2 | -8029 |
| Grm4 | -7366 |
| Grm7 | -6646 |
| Casr | -5400 |
| Grm8 | -4660 |
| Gabbr1 | -3159 |
| Grm5 | -2797 |
| Grm1 | -2628 |
| Grm3 | -2113 |
| Tas1r1 | -1400 |
| Tas1r3 | 1374 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Grm2 | -8216 |
| Gabbr2 | -8029 |
| Grm4 | -7366 |
| Grm7 | -6646 |
| Casr | -5400 |
| Grm8 | -4660 |
| Gabbr1 | -3159 |
| Grm5 | -2797 |
| Grm1 | -2628 |
| Grm3 | -2113 |
| Tas1r1 | -1400 |
| Tas1r3 | 1374 |
SEROTONIN NEUROTRANSMITTER RELEASE CYCLE
| set | SEROTONIN NEUROTRANSMITTER RELEASE CYCLE |
| setSize | 18 |
| pANOVA | 0.000195 |
| s.dist | -0.507 |
| p.adjustANOVA | 0.00282 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Snap25 | -7959 |
| Slc18a2 | -7320 |
| Stxbp1 | -6855 |
| Syn1 | -6817 |
| Syt1 | -6725 |
| Ppfia2 | -6016 |
| Syn2 | -5142 |
| Ppfia1 | -4819 |
| Tspoap1 | -4694 |
| Stx1a | -4521 |
| Rab3a | -4200 |
| Unc13b | -3941 |
| Rims1 | -3759 |
| Syn3 | -3689 |
| Cplx1 | -3550 |
| Ppfia4 | -1765 |
| Ppfia3 | -157 |
| Vamp2 | 6733 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Snap25 | -7959 |
| Slc18a2 | -7320 |
| Stxbp1 | -6855 |
| Syn1 | -6817 |
| Syt1 | -6725 |
| Ppfia2 | -6016 |
| Syn2 | -5142 |
| Ppfia1 | -4819 |
| Tspoap1 | -4694 |
| Stx1a | -4521 |
| Rab3a | -4200 |
| Unc13b | -3941 |
| Rims1 | -3759 |
| Syn3 | -3689 |
| Cplx1 | -3550 |
| Ppfia4 | -1765 |
| Ppfia3 | -157 |
| Vamp2 | 6733 |
ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS
| set | ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS |
| setSize | 10 |
| pANOVA | 0.00611 |
| s.dist | -0.501 |
| p.adjustANOVA | 0.045 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Chrna6 | -8382 |
| Chrnb3 | -8347 |
| Chrna4 | -7671 |
| Chrna1 | -7135 |
| Chrna7 | -5502 |
| Chrna5 | -5297 |
| Chrnb2 | -2518 |
| Chrna2 | -1457 |
| Chrna3 | 522 |
| Chrnb4 | 4542 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Chrna6 | -8382 |
| Chrnb3 | -8347 |
| Chrna4 | -7671 |
| Chrna1 | -7135 |
| Chrna7 | -5502 |
| Chrna5 | -5297 |
| Chrnb2 | -2518 |
| Chrna2 | -1457 |
| Chrna3 | 522 |
| Chrnb4 | 4542 |
HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS
| set | HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS |
| setSize | 10 |
| pANOVA | 0.00611 |
| s.dist | -0.501 |
| p.adjustANOVA | 0.045 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Chrna6 | -8382 |
| Chrnb3 | -8347 |
| Chrna4 | -7671 |
| Chrna1 | -7135 |
| Chrna7 | -5502 |
| Chrna5 | -5297 |
| Chrnb2 | -2518 |
| Chrna2 | -1457 |
| Chrna3 | 522 |
| Chrnb4 | 4542 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Chrna6 | -8382 |
| Chrnb3 | -8347 |
| Chrna4 | -7671 |
| Chrna1 | -7135 |
| Chrna7 | -5502 |
| Chrna5 | -5297 |
| Chrnb2 | -2518 |
| Chrna2 | -1457 |
| Chrna3 | 522 |
| Chrnb4 | 4542 |
ENDOSOMAL VACUOLAR PATHWAY
| set | ENDOSOMAL VACUOLAR PATHWAY |
| setSize | 11 |
| pANOVA | 0.00483 |
| s.dist | 0.491 |
| p.adjustANOVA | 0.0377 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| B2m | 6647 |
| H2-Q7 | 6536 |
| H2-Q2 | 5329 |
| H2-T23 | 5215 |
| Ctsl | 4952 |
| H2-Bl | 4802 |
| H2-D1 | 4745 |
| H2-Q10 | 4365 |
| Ctss | 2955 |
| Lnpep | 2504 |
| H2-M3 | -248 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| B2m | 6647 |
| H2-Q7 | 6536 |
| H2-Q2 | 5329 |
| H2-T23 | 5215 |
| Ctsl | 4952 |
| H2-Bl | 4802 |
| H2-D1 | 4745 |
| H2-Q10 | 4365 |
| Ctss | 2955 |
| Lnpep | 2504 |
| H2-M3 | -248 |
SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX
| set | SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX |
| setSize | 13 |
| pANOVA | 0.00316 |
| s.dist | 0.473 |
| p.adjustANOVA | 0.0265 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Ptgis | 8576 |
| Tbxas1 | 8492 |
| Ptgds | 8159 |
| Hpgd | 8096 |
| Prxl2b | 7999 |
| Ptges3 | 7445 |
| Ptges2 | 7146 |
| Ptges | 2442 |
| Ptgr2 | 2136 |
| Hpgds | 2090 |
| Ptgs1 | 155 |
| Cbr1 | -38 |
| Ptgs2 | -8199 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Ptgis | 8576 |
| Tbxas1 | 8492 |
| Ptgds | 8159 |
| Hpgd | 8096 |
| Prxl2b | 7999 |
| Ptges3 | 7445 |
| Ptges2 | 7146 |
| Ptges | 2442 |
| Ptgr2 | 2136 |
| Hpgds | 2090 |
| Ptgs1 | 155 |
| Cbr1 | -38 |
| Ptgs2 | -8199 |
REGULATION OF EXPRESSION OF SLITS AND ROBOS
| set | REGULATION OF EXPRESSION OF SLITS AND ROBOS |
| setSize | 160 |
| pANOVA | 9.48e-25 |
| s.dist | 0.47 |
| p.adjustANOVA | 1.4e-22 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Rps29 | 8325 |
| Rpl39 | 8217 |
| Psme2 | 8167 |
| Rps21 | 8165 |
| Rpl3 | 8059 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Rps28 | 7899 |
| Rpl38 | 7881 |
| Rps19 | 7880 |
| Rpsa | 7818 |
| Magoh | 7812 |
| Rpl35 | 7727 |
| Rplp2 | 7724 |
| Rpl36 | 7707 |
| Rplp1 | 7699 |
| Rps27a | 7650 |
| Rps9 | 7591 |
| Rps3 | 7581 |
| Rpl13a | 7538 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Rps29 | 8325 |
| Rpl39 | 8217 |
| Psme2 | 8167 |
| Rps21 | 8165 |
| Rpl3 | 8059 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Rps28 | 7899 |
| Rpl38 | 7881 |
| Rps19 | 7880 |
| Rpsa | 7818 |
| Magoh | 7812 |
| Rpl35 | 7727 |
| Rplp2 | 7724 |
| Rpl36 | 7707 |
| Rplp1 | 7699 |
| Rps27a | 7650 |
| Rps9 | 7591 |
| Rps3 | 7581 |
| Rpl13a | 7538 |
| Fau | 7502 |
| Rps6 | 7496 |
| Rpl8 | 7495 |
| Rps3a1 | 7466 |
| Rpl22l1 | 7456 |
| Rps5 | 7446 |
| Rps8 | 7442 |
| Psmb2 | 7416 |
| Rpl37a | 7406 |
| Uba52 | 7390 |
| Rpl27a | 7368 |
| Rps10 | 7263 |
| Rpl18a | 7262 |
| Rps12 | 7244 |
| Rpl13 | 7240 |
| Rps24 | 7234 |
| Rpl9 | 7223 |
| Psma3 | 7211 |
| Sem1 | 7197 |
| Rps14 | 7194 |
| Rps16 | 7180 |
| Rps13 | 7176 |
| Rps23 | 7139 |
| Rpl36al | 7116 |
| Rpl34 | 7060 |
| Rpl27 | 7054 |
| Rps15 | 7047 |
| Psmd13 | 6995 |
| Rps27l | 6994 |
| Rpl23 | 6935 |
| Psmd3 | 6933 |
| Rpl19 | 6905 |
| Rpl37 | 6889 |
| Rpl32 | 6870 |
| Rpl18 | 6859 |
| Psmd10 | 6835 |
| Rpl31 | 6770 |
| Psmd14 | 6756 |
| Psmd9 | 6720 |
| Rps17 | 6719 |
| Ncbp1 | 6701 |
| Psmc5 | 6669 |
| Rpl14 | 6633 |
| Rpl23a | 6576 |
| Rps4x | 6516 |
| Rpl35a | 6487 |
| Rps15a | 6468 |
| Rpl21 | 6433 |
| Rplp0 | 6389 |
| Elob | 6367 |
| Rpl36a | 6363 |
| Rpl17 | 6354 |
| Rps25 | 6317 |
| Rpl30 | 6288 |
| Rbm8a | 6262 |
| Psmb7 | 6239 |
| Psmc3 | 6233 |
| Psmb4 | 6222 |
| Rpl4 | 6203 |
| Psmb5 | 6186 |
| Rpl7 | 6140 |
| Psmd8 | 6112 |
| Rpl10a | 6104 |
| Psma1 | 6039 |
| Isl1 | 5986 |
| Rpl24 | 5910 |
| Psmc4 | 5879 |
| Psmd7 | 5877 |
| Rpl10 | 5873 |
| Rps11 | 5845 |
| Psmb1 | 5844 |
| Rpl5 | 5817 |
| Psmb10 | 5781 |
| Rpl11 | 5763 |
| Rps26 | 5705 |
| Psmb6 | 5649 |
| Rpl22 | 5587 |
| Pabpc1 | 5562 |
| Psmb3 | 5551 |
| Rpl15 | 5502 |
| Rpl26 | 5476 |
| Psmd6 | 5161 |
| Rpl12 | 4905 |
| Rpl29 | 4830 |
| Psma7 | 4674 |
| Psma2 | 4614 |
| Rpl6 | 4589 |
| Psme1 | 4564 |
| Psma6 | 4555 |
| Rps18 | 4496 |
| Rpl7a | 4328 |
| Rpl28 | 4170 |
| Psmb8 | 3669 |
| Psma5 | 3570 |
| Eif4a3 | 3538 |
| Psmd4 | 3516 |
| Rps7 | 3275 |
| Psme3 | 3265 |
| Col4a5 | 2477 |
| Rps2 | 2143 |
| Psma4 | 1887 |
| Rbx1 | 1817 |
| Psmc1 | 1380 |
| Eloc | 1095 |
| Dag1 | 929 |
| Psmb9 | 907 |
| Psmd11 | 828 |
| Psmc2 | 431 |
| Ubb | 86 |
| Upf2 | -51 |
| Psmf1 | -380 |
| Upf3b | -603 |
| Psmd2 | -922 |
| Psmd5 | -1283 |
| Upf3a | -1445 |
| Rnps1 | -2027 |
| Psmd1 | -2046 |
| Eif4g1 | -2240 |
| Gspt1 | -2349 |
| Psme4 | -2417 |
| Ldb1 | -2536 |
| Robo1 | -3170 |
| Zswim8 | -3685 |
| Cul2 | -3771 |
| Msi1 | -3998 |
| Casc3 | -4016 |
| Usp33 | -4017 |
| Lhx2 | -4681 |
| Slit2 | -4682 |
| Gspt2 | -4765 |
| Robo2 | -5165 |
| Psmc6 | -5260 |
| Ncbp2 | -5269 |
| Etf1 | -5342 |
| Robo3 | -5970 |
| Lhx9 | -6266 |
| Magohb | -6733 |
| Slit1 | -6972 |
| Ubc | -7102 |
| Psmd12 | -7851 |
RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS
| set | RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS |
| setSize | 125 |
| pANOVA | 5.98e-19 |
| s.dist | 0.46 |
| p.adjustANOVA | 7.05e-17 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Atp5g2 | 8457 |
| mt-Atp8 | 8090 |
| Slc25a14 | 8011 |
| Ndufa2 | 7963 |
| mt-Nd3 | 7923 |
| Ndufb2 | 7696 |
| Ucp2 | 7676 |
| mt-Nd6 | 7500 |
| Atp5e | 7419 |
| Ndufaf5 | 7376 |
| Cox6a1 | 7373 |
| Ndufa1 | 7278 |
| Pm20d1 | 7235 |
| Atp5k | 7191 |
| Ndufs3 | 7185 |
| mt-Nd5 | 7002 |
| Surf1 | 6986 |
| Ndufaf1 | 6861 |
| mt-Co1 | 6740 |
| Ndufb10 | 6726 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Atp5g2 | 8457 |
| mt-Atp8 | 8090 |
| Slc25a14 | 8011 |
| Ndufa2 | 7963 |
| mt-Nd3 | 7923 |
| Ndufb2 | 7696 |
| Ucp2 | 7676 |
| mt-Nd6 | 7500 |
| Atp5e | 7419 |
| Ndufaf5 | 7376 |
| Cox6a1 | 7373 |
| Ndufa1 | 7278 |
| Pm20d1 | 7235 |
| Atp5k | 7191 |
| Ndufs3 | 7185 |
| mt-Nd5 | 7002 |
| Surf1 | 6986 |
| Ndufaf1 | 6861 |
| mt-Co1 | 6740 |
| Ndufb10 | 6726 |
| Timmdc1 | 6716 |
| mt-Nd4 | 6667 |
| Ndufb11 | 6666 |
| mt-Nd2 | 6657 |
| Ndufaf7 | 6650 |
| Ndufv1 | 6606 |
| Ndufb9 | 6566 |
| Ndufb1 | 6523 |
| Atp5l | 6507 |
| mt-Atp6 | 6401 |
| Atp5h | 6283 |
| Cox7a2l | 6275 |
| Ecsit | 6255 |
| Ndufs6 | 6240 |
| mt-Cytb | 6215 |
| Cox4i1 | 6200 |
| mt-Nd1 | 6157 |
| mt-Co2 | 6148 |
| Ndufa3 | 6040 |
| Coq10b | 6034 |
| Cox5b | 6025 |
| Ndufaf6 | 6023 |
| Ndufb8 | 6022 |
| Atp5g3 | 6018 |
| Uqcrq | 5997 |
| Uqcrh | 5950 |
| Ndufa7 | 5942 |
| Ndufc2 | 5918 |
| Ndufc1 | 5901 |
| Ndufb4 | 5866 |
| mt-Co3 | 5862 |
| Uqcr11 | 5770 |
| Ndufa6 | 5748 |
| Etfb | 5714 |
| Uqcr10 | 5704 |
| Cox8a | 5665 |
| Cyc1 | 5609 |
| Ndufab1 | 5531 |
| Cox6b1 | 5521 |
| Cox16 | 5508 |
| Ndufs5 | 5396 |
| Ndufa13 | 5381 |
| Atp5d | 5331 |
| Cox5a | 5222 |
| Cox7c | 5208 |
| Cox20 | 5192 |
| Ndufa11 | 5153 |
| Ndufa5 | 5144 |
| Cox6c | 5015 |
| Ndufb7 | 4964 |
| Ndufb6 | 4790 |
| Ndufb5 | 4719 |
| Sdhc | 4680 |
| Ndufaf3 | 4397 |
| Ndufa4 | 4306 |
| Ndufs7 | 4138 |
| Taco1 | 3936 |
| Nubpl | 3930 |
| Atp5j2 | 3902 |
| Atp5j | 3861 |
| Ndufs2 | 3779 |
| Ndufa12 | 3663 |
| Uqcrc1 | 3657 |
| Etfa | 3585 |
| Ndufs4 | 3561 |
| Atp5c1 | 3539 |
| Atp5a1 | 3507 |
| Atp5g1 | 3376 |
| Ndufa8 | 3300 |
| Ndufv3 | 3082 |
| Ndufs8 | 3026 |
| Uqcrb | 2967 |
| Cox18 | 2930 |
| Sdhb | 2831 |
| Atp5b | 2773 |
| Cox7b | 2719 |
| Trap1 | 2673 |
| Sdhd | 2560 |
| Ndufv2 | 2411 |
| Cox14 | 2152 |
| Ndufb3 | 2058 |
| Dmac2l | 1976 |
| Coq10a | 1695 |
| Uqcrfs1 | 1408 |
| Ndufaf2 | 1345 |
| Cox11 | 1344 |
| Cycs | 1132 |
| Ndufa9 | 886 |
| Atp5pb | 826 |
| Atp5o | 98 |
| Acad9 | -240 |
| Cox19 | -1027 |
| Uqcrc2 | -1109 |
| Sco2 | -1171 |
| Tmem126b | -1183 |
| Ndufaf4 | -2005 |
| Ndufa10 | -3073 |
| Ndufs1 | -3913 |
| Sdha | -4496 |
| Etfdh | -4499 |
| Ucp3 | -5644 |
| Sco1 | -5724 |
| Lrpprc | -6291 |
| Tmem186 | -7055 |
| Slc25a27 | -7309 |
RESPIRATORY ELECTRON TRANSPORT
| set | RESPIRATORY ELECTRON TRANSPORT |
| setSize | 102 |
| pANOVA | 1.43e-15 |
| s.dist | 0.457 |
| p.adjustANOVA | 1.41e-13 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Ndufa2 | 7963 |
| mt-Nd3 | 7923 |
| Ndufb2 | 7696 |
| mt-Nd6 | 7500 |
| Ndufaf5 | 7376 |
| Cox6a1 | 7373 |
| Ndufa1 | 7278 |
| Ndufs3 | 7185 |
| mt-Nd5 | 7002 |
| Surf1 | 6986 |
| Ndufaf1 | 6861 |
| mt-Co1 | 6740 |
| Ndufb10 | 6726 |
| Timmdc1 | 6716 |
| mt-Nd4 | 6667 |
| Ndufb11 | 6666 |
| mt-Nd2 | 6657 |
| Ndufaf7 | 6650 |
| Ndufv1 | 6606 |
| Ndufb9 | 6566 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Ndufa2 | 7963 |
| mt-Nd3 | 7923 |
| Ndufb2 | 7696 |
| mt-Nd6 | 7500 |
| Ndufaf5 | 7376 |
| Cox6a1 | 7373 |
| Ndufa1 | 7278 |
| Ndufs3 | 7185 |
| mt-Nd5 | 7002 |
| Surf1 | 6986 |
| Ndufaf1 | 6861 |
| mt-Co1 | 6740 |
| Ndufb10 | 6726 |
| Timmdc1 | 6716 |
| mt-Nd4 | 6667 |
| Ndufb11 | 6666 |
| mt-Nd2 | 6657 |
| Ndufaf7 | 6650 |
| Ndufv1 | 6606 |
| Ndufb9 | 6566 |
| Ndufb1 | 6523 |
| Cox7a2l | 6275 |
| Ecsit | 6255 |
| Ndufs6 | 6240 |
| mt-Cytb | 6215 |
| Cox4i1 | 6200 |
| mt-Nd1 | 6157 |
| mt-Co2 | 6148 |
| Ndufa3 | 6040 |
| Coq10b | 6034 |
| Cox5b | 6025 |
| Ndufaf6 | 6023 |
| Ndufb8 | 6022 |
| Uqcrq | 5997 |
| Uqcrh | 5950 |
| Ndufa7 | 5942 |
| Ndufc2 | 5918 |
| Ndufc1 | 5901 |
| Ndufb4 | 5866 |
| mt-Co3 | 5862 |
| Uqcr11 | 5770 |
| Ndufa6 | 5748 |
| Etfb | 5714 |
| Uqcr10 | 5704 |
| Cox8a | 5665 |
| Cyc1 | 5609 |
| Ndufab1 | 5531 |
| Cox6b1 | 5521 |
| Cox16 | 5508 |
| Ndufs5 | 5396 |
| Ndufa13 | 5381 |
| Cox5a | 5222 |
| Cox7c | 5208 |
| Cox20 | 5192 |
| Ndufa11 | 5153 |
| Ndufa5 | 5144 |
| Cox6c | 5015 |
| Ndufb7 | 4964 |
| Ndufb6 | 4790 |
| Ndufb5 | 4719 |
| Sdhc | 4680 |
| Ndufaf3 | 4397 |
| Ndufa4 | 4306 |
| Ndufs7 | 4138 |
| Taco1 | 3936 |
| Nubpl | 3930 |
| Ndufs2 | 3779 |
| Ndufa12 | 3663 |
| Uqcrc1 | 3657 |
| Etfa | 3585 |
| Ndufs4 | 3561 |
| Ndufa8 | 3300 |
| Ndufv3 | 3082 |
| Ndufs8 | 3026 |
| Uqcrb | 2967 |
| Cox18 | 2930 |
| Sdhb | 2831 |
| Cox7b | 2719 |
| Trap1 | 2673 |
| Sdhd | 2560 |
| Ndufv2 | 2411 |
| Cox14 | 2152 |
| Ndufb3 | 2058 |
| Coq10a | 1695 |
| Uqcrfs1 | 1408 |
| Ndufaf2 | 1345 |
| Cox11 | 1344 |
| Cycs | 1132 |
| Ndufa9 | 886 |
| Acad9 | -240 |
| Cox19 | -1027 |
| Uqcrc2 | -1109 |
| Sco2 | -1171 |
| Tmem126b | -1183 |
| Ndufaf4 | -2005 |
| Ndufa10 | -3073 |
| Ndufs1 | -3913 |
| Sdha | -4496 |
| Etfdh | -4499 |
| Sco1 | -5724 |
| Lrpprc | -6291 |
| Tmem186 | -7055 |
NEUROTOXICITY OF CLOSTRIDIUM TOXINS
| set | NEUROTOXICITY OF CLOSTRIDIUM TOXINS |
| setSize | 10 |
| pANOVA | 0.0133 |
| s.dist | -0.452 |
| p.adjustANOVA | 0.0841 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Snap25 | -7959 |
| Sv2b | -7037 |
| Syt1 | -6725 |
| Stx1b | -5807 |
| Vamp1 | -5125 |
| Stx1a | -4521 |
| Sv2a | -3052 |
| Syt2 | -2657 |
| Sv2c | -955 |
| Vamp2 | 6733 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Snap25 | -7959 |
| Sv2b | -7037 |
| Syt1 | -6725 |
| Stx1b | -5807 |
| Vamp1 | -5125 |
| Stx1a | -4521 |
| Sv2a | -3052 |
| Syt2 | -2657 |
| Sv2c | -955 |
| Vamp2 | 6733 |
HDR THROUGH MMEJ ALT NHEJ
| set | HDR THROUGH MMEJ ALT NHEJ |
| setSize | 10 |
| pANOVA | 0.0136 |
| s.dist | -0.451 |
| p.adjustANOVA | 0.085 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Rbbp8 | -8294 |
| Rad50 | -7884 |
| Parp1 | -7496 |
| Nbn | -7293 |
| Fen1 | -7155 |
| Parp2 | -4740 |
| Lig3 | -2437 |
| Mre11a | 129 |
| Polq | 365 |
| Xrcc1 | 7822 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Rbbp8 | -8294 |
| Rad50 | -7884 |
| Parp1 | -7496 |
| Nbn | -7293 |
| Fen1 | -7155 |
| Parp2 | -4740 |
| Lig3 | -2437 |
| Mre11a | 129 |
| Polq | 365 |
| Xrcc1 | 7822 |
CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND
| set | CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND |
| setSize | 10 |
| pANOVA | 0.0145 |
| s.dist | -0.446 |
| p.adjustANOVA | 0.088 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Unc5a | -8203 |
| Unc5b | -8178 |
| Dapk2 | -5691 |
| Appl1 | -4320 |
| Maged1 | -3858 |
| Dapk1 | -3670 |
| Casp9 | -3519 |
| Dcc | -1809 |
| Casp3 | -1381 |
| Dapk3 | 4017 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Unc5a | -8203 |
| Unc5b | -8178 |
| Dapk2 | -5691 |
| Appl1 | -4320 |
| Maged1 | -3858 |
| Dapk1 | -3670 |
| Casp9 | -3519 |
| Dcc | -1809 |
| Casp3 | -1381 |
| Dapk3 | 4017 |
GLUTATHIONE CONJUGATION
| set | GLUTATHIONE CONJUGATION |
| setSize | 29 |
| pANOVA | 5.58e-05 |
| s.dist | 0.432 |
| p.adjustANOVA | 0.00111 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Oplah | 8377 |
| Cndp2 | 7974 |
| Gsto1 | 7626 |
| Ggct | 7323 |
| Gss | 7318 |
| Gstt2 | 7169 |
| Ggt5 | 7135 |
| Gstp2 | 7028 |
| Akr1a1 | 6816 |
| Gstm7 | 6560 |
| Gsta3 | 5671 |
| Gstk1 | 5118 |
| Esd | 5071 |
| Ggt1 | 4927 |
| Mgst1 | 4693 |
| Gstp1 | 4517 |
| Gstm2 | 4479 |
| Gstm4 | 3985 |
| Gstm5 | 3651 |
| Gstm1 | 3580 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Oplah | 8377 |
| Cndp2 | 7974 |
| Gsto1 | 7626 |
| Ggct | 7323 |
| Gss | 7318 |
| Gstt2 | 7169 |
| Ggt5 | 7135 |
| Gstp2 | 7028 |
| Akr1a1 | 6816 |
| Gstm7 | 6560 |
| Gsta3 | 5671 |
| Gstk1 | 5118 |
| Esd | 5071 |
| Ggt1 | 4927 |
| Mgst1 | 4693 |
| Gstp1 | 4517 |
| Gstm2 | 4479 |
| Gstm4 | 3985 |
| Gstm5 | 3651 |
| Gstm1 | 3580 |
| Gstz1 | 2642 |
| Hpgds | 2090 |
| Gclm | 1220 |
| Chac1 | 917 |
| Mgst3 | 258 |
| Chac2 | -1930 |
| Ggt7 | -2812 |
| Gclc | -4209 |
| Gsto2 | -5735 |
SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL
| set | SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL |
| setSize | 12 |
| pANOVA | 0.00999 |
| s.dist | 0.43 |
| p.adjustANOVA | 0.0676 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Ptgis | 8576 |
| Hsd3b7 | 8559 |
| Cyp7b1 | 8041 |
| Slc27a2 | 7309 |
| Scp2 | 6946 |
| Acot8 | 6631 |
| Rxra | 5401 |
| Amacr | 2743 |
| Hsd17b4 | 1888 |
| Ncoa2 | -2202 |
| Ncoa1 | -2994 |
| Cyp27a1 | -5023 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Ptgis | 8576 |
| Hsd3b7 | 8559 |
| Cyp7b1 | 8041 |
| Slc27a2 | 7309 |
| Scp2 | 6946 |
| Acot8 | 6631 |
| Rxra | 5401 |
| Amacr | 2743 |
| Hsd17b4 | 1888 |
| Ncoa2 | -2202 |
| Ncoa1 | -2994 |
| Cyp27a1 | -5023 |
PHASE 4 RESTING MEMBRANE POTENTIAL
| set | PHASE 4 RESTING MEMBRANE POTENTIAL |
| setSize | 14 |
| pANOVA | 0.00604 |
| s.dist | -0.424 |
| p.adjustANOVA | 0.045 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Kcnk10 | -7624 |
| Kcnj2 | -7542 |
| Kcnj14 | -7426 |
| Kcnk9 | -7333 |
| Kcnk4 | -6897 |
| Kcnk3 | -5985 |
| Kcnk13 | -5817 |
| Kcnj4 | -3948 |
| Kcnk5 | -3050 |
| Kcnj12 | -2375 |
| Kcnk1 | -1317 |
| Kcnk2 | 1615 |
| Kcnk6 | 2946 |
| Kcnk12 | 6216 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Kcnk10 | -7624 |
| Kcnj2 | -7542 |
| Kcnj14 | -7426 |
| Kcnk9 | -7333 |
| Kcnk4 | -6897 |
| Kcnk3 | -5985 |
| Kcnk13 | -5817 |
| Kcnj4 | -3948 |
| Kcnk5 | -3050 |
| Kcnj12 | -2375 |
| Kcnk1 | -1317 |
| Kcnk2 | 1615 |
| Kcnk6 | 2946 |
| Kcnk12 | 6216 |
DSCAM INTERACTIONS
| set | DSCAM INTERACTIONS |
| setSize | 10 |
| pANOVA | 0.0207 |
| s.dist | -0.423 |
| p.adjustANOVA | 0.113 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Mapk8 | -7465 |
| Pak1 | -6411 |
| Dscam | -5784 |
| Ntn1 | -4877 |
| Mapk11 | -4774 |
| Dscaml1 | -3542 |
| Mapk12 | -2605 |
| Dcc | -1809 |
| Mapk14 | -1646 |
| Rac1 | 4340 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Mapk8 | -7465 |
| Pak1 | -6411 |
| Dscam | -5784 |
| Ntn1 | -4877 |
| Mapk11 | -4774 |
| Dscaml1 | -3542 |
| Mapk12 | -2605 |
| Dcc | -1809 |
| Mapk14 | -1646 |
| Rac1 | 4340 |
RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA
| set | RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA |
| setSize | 24 |
| pANOVA | 0.000377 |
| s.dist | -0.419 |
| p.adjustANOVA | 0.00454 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Blm | -8384 |
| Rbbp8 | -8294 |
| Xrcc3 | -7967 |
| Rad50 | -7884 |
| Rad51 | -7849 |
| Rad51d | -7587 |
| Palb2 | -7389 |
| Nbn | -7293 |
| Rad51ap1 | -7237 |
| Top3a | -6628 |
| Wrn | -6578 |
| Dna2 | -6229 |
| Rmi2 | -5721 |
| Kat5 | -5326 |
| Rtel1 | -4761 |
| Rad51c | -4066 |
| Bard1 | -2086 |
| Mre11a | 129 |
| Atm | 286 |
| Rmi1 | 2827 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Blm | -8384 |
| Rbbp8 | -8294 |
| Xrcc3 | -7967 |
| Rad50 | -7884 |
| Rad51 | -7849 |
| Rad51d | -7587 |
| Palb2 | -7389 |
| Nbn | -7293 |
| Rad51ap1 | -7237 |
| Top3a | -6628 |
| Wrn | -6578 |
| Dna2 | -6229 |
| Rmi2 | -5721 |
| Kat5 | -5326 |
| Rtel1 | -4761 |
| Rad51c | -4066 |
| Bard1 | -2086 |
| Mre11a | 129 |
| Atm | 286 |
| Rmi1 | 2827 |
| Brca2 | 4100 |
| Brca1 | 6945 |
| Xrcc2 | 7259 |
| Brip1 | 7515 |
CELLULAR RESPONSE TO STARVATION
| set | CELLULAR RESPONSE TO STARVATION |
| setSize | 146 |
| pANOVA | 4.58e-18 |
| s.dist | 0.415 |
| p.adjustANOVA | 4.9e-16 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Castor1 | 8512 |
| Mlst8 | 8503 |
| Rps29 | 8325 |
| Atp6v1c2 | 8304 |
| Rpl39 | 8217 |
| Rps21 | 8165 |
| Atp6v0e | 8109 |
| Rpl3 | 8059 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Rps28 | 7899 |
| Rpl38 | 7881 |
| Rps19 | 7880 |
| Rpsa | 7818 |
| Rpl35 | 7727 |
| Rplp2 | 7724 |
| Rpl36 | 7707 |
| Rplp1 | 7699 |
| Kptn | 7689 |
| Rps27a | 7650 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Castor1 | 8512 |
| Mlst8 | 8503 |
| Rps29 | 8325 |
| Atp6v1c2 | 8304 |
| Rpl39 | 8217 |
| Rps21 | 8165 |
| Atp6v0e | 8109 |
| Rpl3 | 8059 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Rps28 | 7899 |
| Rpl38 | 7881 |
| Rps19 | 7880 |
| Rpsa | 7818 |
| Rpl35 | 7727 |
| Rplp2 | 7724 |
| Rpl36 | 7707 |
| Rplp1 | 7699 |
| Kptn | 7689 |
| Rps27a | 7650 |
| Rps9 | 7591 |
| Rps3 | 7581 |
| Rpl13a | 7538 |
| Fau | 7502 |
| Rps6 | 7496 |
| Rpl8 | 7495 |
| Rps3a1 | 7466 |
| Rpl22l1 | 7456 |
| Rps5 | 7446 |
| Rps8 | 7442 |
| Rpl37a | 7406 |
| Uba52 | 7390 |
| Rpl27a | 7368 |
| Rps10 | 7263 |
| Rpl18a | 7262 |
| Rps12 | 7244 |
| Rpl13 | 7240 |
| Rps24 | 7234 |
| Rpl9 | 7223 |
| Rps14 | 7194 |
| Rps16 | 7180 |
| Rps13 | 7176 |
| Rps23 | 7139 |
| Rpl36al | 7116 |
| Rpl34 | 7060 |
| Rpl27 | 7054 |
| Rps15 | 7047 |
| Rps27l | 6994 |
| Rpl23 | 6935 |
| Rpl19 | 6905 |
| Rpl37 | 6889 |
| Rpl32 | 6870 |
| Rpl18 | 6859 |
| Rpl31 | 6770 |
| Rps17 | 6719 |
| Rpl14 | 6633 |
| Rpl23a | 6576 |
| Lamtor2 | 6553 |
| Rps4x | 6516 |
| Rpl35a | 6487 |
| Rps15a | 6468 |
| Rpl21 | 6433 |
| Rplp0 | 6389 |
| Rpl36a | 6363 |
| Rpl17 | 6354 |
| Rps25 | 6317 |
| Rpl30 | 6288 |
| Rpl4 | 6203 |
| Rpl7 | 6140 |
| Rpl10a | 6104 |
| Wdr24 | 5952 |
| Rpl24 | 5910 |
| Rpl10 | 5873 |
| Rps11 | 5845 |
| Rpl5 | 5817 |
| Rpl11 | 5763 |
| Rps26 | 5705 |
| Rpl22 | 5587 |
| Rpl15 | 5502 |
| Rpl26 | 5476 |
| Atp6v1g1 | 5160 |
| Rpl12 | 4905 |
| Rpl29 | 4830 |
| Atp6v1f | 4740 |
| Rpl6 | 4589 |
| Rps18 | 4496 |
| Nprl2 | 4476 |
| Lamtor1 | 4375 |
| Rpl7a | 4328 |
| Rpl28 | 4170 |
| Atp6v1h | 4123 |
| Ddit3 | 4082 |
| Atp6v0b | 4021 |
| Eif2s3x | 3871 |
| Eif2s2 | 3839 |
| Castor2 | 3544 |
| Rps7 | 3275 |
| Rheb | 2958 |
| Lamtor4 | 2840 |
| Trib3 | 2830 |
| Lamtor5 | 2740 |
| Tcirg1 | 2569 |
| Atp6v0c | 2424 |
| Impact | 2367 |
| Rps2 | 2143 |
| Gcn1 | 1962 |
| Atf3 | 1512 |
| Sec13 | 1308 |
| Atp6v0e2 | 1097 |
| Mios | 1096 |
| Szt2 | 1038 |
| Itfg2 | 872 |
| Lamtor3 | 740 |
| Fnip1 | 727 |
| Atp6v1e1 | -196 |
| Atf4 | -536 |
| Slc38a9 | -597 |
| Atp6v1a | -692 |
| Rptor | -746 |
| Cebpg | -983 |
| Atp6v1d | -1485 |
| Sesn1 | -1559 |
| Depdc5 | -2003 |
| Wdr59 | -2112 |
| Eif2s1 | -2149 |
| Atp6v0d1 | -2204 |
| Nprl3 | -2473 |
| Cebpb | -2830 |
| Sh3bp4 | -3811 |
| Rragb | -4767 |
| Flcn | -5391 |
| Rragc | -5457 |
| Mtor | -5458 |
| Atp6v1c1 | -5664 |
| Rraga | -5881 |
| Atp6v1b2 | -6061 |
| Atf2 | -6236 |
| Bmt2 | -6338 |
| Asns | -6356 |
| Rragd | -6395 |
| Seh1l | -6781 |
| Sesn2 | -7161 |
| Eif2ak4 | -7339 |
| Fnip2 | -7416 |
| BC048403 | -7968 |
| Atp6v1g2 | -8275 |
CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES
| set | CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES |
| setSize | 46 |
| pANOVA | 1.19e-06 |
| s.dist | 0.414 |
| p.adjustANOVA | 4.39e-05 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Psme2 | 8167 |
| Psmb2 | 7416 |
| Psma3 | 7211 |
| Sem1 | 7197 |
| Psmd13 | 6995 |
| Psmd3 | 6933 |
| Psmd10 | 6835 |
| Psmd14 | 6756 |
| Psmd9 | 6720 |
| Psmc5 | 6669 |
| Psmb7 | 6239 |
| Psmc3 | 6233 |
| Psmb4 | 6222 |
| Psmb5 | 6186 |
| Psmd8 | 6112 |
| Psma1 | 6039 |
| Mrc2 | 5958 |
| Psmc4 | 5879 |
| Psmd7 | 5877 |
| Psmb1 | 5844 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Psme2 | 8167 |
| Psmb2 | 7416 |
| Psma3 | 7211 |
| Sem1 | 7197 |
| Psmd13 | 6995 |
| Psmd3 | 6933 |
| Psmd10 | 6835 |
| Psmd14 | 6756 |
| Psmd9 | 6720 |
| Psmc5 | 6669 |
| Psmb7 | 6239 |
| Psmc3 | 6233 |
| Psmb4 | 6222 |
| Psmb5 | 6186 |
| Psmd8 | 6112 |
| Psma1 | 6039 |
| Mrc2 | 5958 |
| Psmc4 | 5879 |
| Psmd7 | 5877 |
| Psmb1 | 5844 |
| Psmb10 | 5781 |
| Psmb6 | 5649 |
| Psmb3 | 5551 |
| Psmd6 | 5161 |
| Psma7 | 4674 |
| Psma2 | 4614 |
| Psme1 | 4564 |
| Psma6 | 4555 |
| Psmb8 | 3669 |
| Psma5 | 3570 |
| Psmd4 | 3516 |
| Psme3 | 3265 |
| Fcgr1 | 1944 |
| Psma4 | 1887 |
| Psmc1 | 1380 |
| Psmb9 | 907 |
| Psmd11 | 828 |
| Psmc2 | 431 |
| Psmf1 | -380 |
| Psmd2 | -922 |
| Psmd5 | -1283 |
| Psmd1 | -2046 |
| Psme4 | -2417 |
| Mrc1 | -3888 |
| Psmc6 | -5260 |
| Psmd12 | -7851 |
MITOCHONDRIAL FATTY ACID BETA OXIDATION
| set | MITOCHONDRIAL FATTY ACID BETA OXIDATION |
| setSize | 34 |
| pANOVA | 2.97e-05 |
| s.dist | 0.414 |
| p.adjustANOVA | 0.000672 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Acot11 | 8638 |
| Hadha | 8110 |
| Acad11 | 7846 |
| Eci1 | 7520 |
| Acsf2 | 7505 |
| Dbi | 7372 |
| Acaa2 | 7295 |
| Pctp | 6803 |
| Acbd6 | 6677 |
| Decr1 | 6629 |
| Acads | 6455 |
| Acbd7 | 6411 |
| Pccb | 6385 |
| Them4 | 5740 |
| Ndufab1 | 5531 |
| Acadm | 5279 |
| Mmut | 5072 |
| Echs1 | 4798 |
| Mcee | 4697 |
| Mmaa | 4369 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Acot11 | 8638 |
| Hadha | 8110 |
| Acad11 | 7846 |
| Eci1 | 7520 |
| Acsf2 | 7505 |
| Dbi | 7372 |
| Acaa2 | 7295 |
| Pctp | 6803 |
| Acbd6 | 6677 |
| Decr1 | 6629 |
| Acads | 6455 |
| Acbd7 | 6411 |
| Pccb | 6385 |
| Them4 | 5740 |
| Ndufab1 | 5531 |
| Acadm | 5279 |
| Mmut | 5072 |
| Echs1 | 4798 |
| Mcee | 4697 |
| Mmaa | 4369 |
| Mcat | 4284 |
| Hadhb | 4192 |
| Acadvl | 3924 |
| Acot13 | 2694 |
| Hadh | 1982 |
| Acadl | 1532 |
| Mecr | 1025 |
| Acot1 | 19 |
| Acad10 | -425 |
| Pcca | -2444 |
| Acot9 | -3650 |
| Acot2 | -5063 |
| Acot3 | -5715 |
| Acot7 | -6220 |
TRANSLATION
| set | TRANSLATION |
| setSize | 286 |
| pANOVA | 7.32e-33 |
| s.dist | 0.41 |
| p.adjustANOVA | 2.87e-30 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Lars2 | 8636 |
| Apeh | 8468 |
| Mrpl23 | 8406 |
| Mrpl51 | 8341 |
| Rps29 | 8325 |
| Eral1 | 8270 |
| Rpl39 | 8217 |
| Mrps35 | 8207 |
| Eif3f | 8193 |
| Rps21 | 8165 |
| Sec61g | 8104 |
| Rpl3 | 8059 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Aimp2 | 7927 |
| Rps28 | 7899 |
| Rpl38 | 7881 |
| Rps19 | 7880 |
| Ssr3 | 7840 |
| Mrps6 | 7838 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Lars2 | 8636 |
| Apeh | 8468 |
| Mrpl23 | 8406 |
| Mrpl51 | 8341 |
| Rps29 | 8325 |
| Eral1 | 8270 |
| Rpl39 | 8217 |
| Mrps35 | 8207 |
| Eif3f | 8193 |
| Rps21 | 8165 |
| Sec61g | 8104 |
| Rpl3 | 8059 |
| Rps20 | 8018 |
| Rps27 | 7935 |
| Aimp2 | 7927 |
| Rps28 | 7899 |
| Rpl38 | 7881 |
| Rps19 | 7880 |
| Ssr3 | 7840 |
| Mrps6 | 7838 |
| Rpsa | 7818 |
| Eif4a1 | 7791 |
| Mrpl9 | 7734 |
| Rpl35 | 7727 |
| Rplp2 | 7724 |
| Rpl36 | 7707 |
| Rplp1 | 7699 |
| Spcs1 | 7680 |
| Rps27a | 7650 |
| Eif3j2 | 7628 |
| Sec61b | 7616 |
| Rps9 | 7591 |
| Rps3 | 7581 |
| Rpl13a | 7538 |
| Fau | 7502 |
| Rps6 | 7496 |
| Rpl8 | 7495 |
| Rps3a1 | 7466 |
| Rpl22l1 | 7456 |
| Rps5 | 7446 |
| Rps8 | 7442 |
| Mrpl52 | 7428 |
| Rpl37a | 7406 |
| Uba52 | 7390 |
| Rpl27a | 7368 |
| Mrpl14 | 7297 |
| Rps10 | 7263 |
| Rpl18a | 7262 |
| Qars | 7261 |
| Eif3b | 7245 |
| Rps12 | 7244 |
| Rpl13 | 7240 |
| Rps24 | 7234 |
| Rpl9 | 7223 |
| Rps14 | 7194 |
| Rps16 | 7180 |
| Rps13 | 7176 |
| Rps23 | 7139 |
| Eef1d | 7127 |
| Mrpl16 | 7120 |
| Rpl36al | 7116 |
| Mrpl47 | 7114 |
| Rpl34 | 7060 |
| Rpl27 | 7054 |
| Rps15 | 7047 |
| Mrpl32 | 7023 |
| Rps27l | 6994 |
| Fars2 | 6982 |
| Eef1b2 | 6956 |
| Rpl23 | 6935 |
| Rpl19 | 6905 |
| Rpl37 | 6889 |
| Rpl32 | 6870 |
| Rpl18 | 6859 |
| Mrps9 | 6823 |
| Mrpl35 | 6791 |
| Tram1 | 6780 |
| Rpl31 | 6770 |
| Chchd1 | 6757 |
| Rps17 | 6719 |
| Mrpl36 | 6683 |
| Eif3l | 6652 |
| Mrps18c | 6638 |
| Rpl14 | 6633 |
| Rpl23a | 6576 |
| Ssr4 | 6529 |
| Rps4x | 6516 |
| Rpl35a | 6487 |
| Eif2b5 | 6486 |
| Rps15a | 6468 |
| Rpl21 | 6433 |
| Rplp0 | 6389 |
| Mrps17 | 6374 |
| Rpl36a | 6363 |
| Rpl17 | 6354 |
| Mrps15 | 6337 |
| Rps25 | 6317 |
| Mrpl53 | 6297 |
| Eef1a1 | 6294 |
| Rpl30 | 6288 |
| Aimp1 | 6270 |
| Mrps23 | 6230 |
| Yars2 | 6226 |
| Rpl4 | 6203 |
| Rpl7 | 6140 |
| Eif3m | 6107 |
| Rpl10a | 6104 |
| Mrpl11 | 6056 |
| Mrpl12 | 5985 |
| Mrpl37 | 5957 |
| Srp19 | 5926 |
| Rpl24 | 5910 |
| Rpl10 | 5873 |
| Rps11 | 5845 |
| Dap3 | 5841 |
| Rpl5 | 5817 |
| Eif2b4 | 5807 |
| Mrpl4 | 5783 |
| Rpl11 | 5763 |
| Eif3e | 5752 |
| Mrpl28 | 5745 |
| Mrps30 | 5728 |
| Rps26 | 5705 |
| Eef1g | 5693 |
| Eef1e1 | 5676 |
| Mrpl24 | 5664 |
| Mrpl34 | 5634 |
| Rpl22 | 5587 |
| Eif3d | 5586 |
| Rpn2 | 5569 |
| Pabpc1 | 5562 |
| Mrpl41 | 5546 |
| Mrpl43 | 5518 |
| Rpl15 | 5502 |
| Rpl26 | 5476 |
| Sec11c | 5451 |
| Eif3i | 5418 |
| Mrpl46 | 5399 |
| Mrps7 | 5147 |
| Eif3k | 5051 |
| Mrpl33 | 4970 |
| Aurkaip1 | 4963 |
| Spcs2 | 4943 |
| Mrps16 | 4906 |
| Rpl12 | 4905 |
| Ssr2 | 4846 |
| Farsa | 4832 |
| Rpl29 | 4830 |
| Mrpl15 | 4794 |
| Mrpl57 | 4755 |
| Mrpl54 | 4716 |
| Mrpl42 | 4707 |
| Mrpl48 | 4655 |
| Mrpl17 | 4652 |
| Eef2 | 4634 |
| Mrps14 | 4613 |
| Rpl6 | 4589 |
| Mrps21 | 4541 |
| Eif4ebp1 | 4505 |
| Rps18 | 4496 |
| Mrps27 | 4488 |
| Tufm | 4465 |
| Mrps33 | 4464 |
| Mrpl20 | 4409 |
| Mrpl2 | 4384 |
| Rpl7a | 4328 |
| Ppa1 | 4279 |
| Eif3h | 4201 |
| Srp9 | 4193 |
| Rpl28 | 4170 |
| Pars2 | 4015 |
| Mrps34 | 3963 |
| Eif2s3x | 3871 |
| Mrpl21 | 3845 |
| Eif2s2 | 3839 |
| Mrps24 | 3796 |
| Oxa1l | 3789 |
| Mrps26 | 3739 |
| Eif4e | 3721 |
| Mrpl27 | 3682 |
| Vars | 3611 |
| Tars2 | 3605 |
| Rpn1 | 3420 |
| Rps7 | 3275 |
| Dars2 | 3257 |
| Mrpl13 | 3064 |
| Sec11a | 3016 |
| Gadd45gip1 | 2922 |
| Ddost | 2887 |
| Trmt112 | 2845 |
| Mtfmt | 2760 |
| Tsfm | 2729 |
| Srp14 | 2676 |
| Mrpl18 | 2609 |
| Mrpl30 | 2551 |
| Srp54a | 2547 |
| Cars2 | 2546 |
| Ppa2 | 2485 |
| Mtrf1l | 2390 |
| Mrps11 | 2197 |
| Rps2 | 2143 |
| Ears2 | 2132 |
| Mrps22 | 2117 |
| Gfm2 | 2091 |
| Vars2 | 2082 |
| Eif3g | 2061 |
| Mrpl58 | 2023 |
| Mrpl3 | 1964 |
| Mrps18b | 1886 |
| Hars2 | 1707 |
| Mrps25 | 1332 |
| Eif2b2 | 1157 |
| Mrpl50 | 1037 |
| Kars | 1027 |
| Eif5b | 996 |
| Iars2 | 941 |
| Mrps18a | 794 |
| Mrpl40 | 704 |
| Mrps12 | 631 |
| Mrpl49 | 539 |
| Sec61a1 | 507 |
| Eif3j1 | 483 |
| Eif2b3 | 454 |
| Mrps28 | 451 |
| Eif3c | 409 |
| Mrpl38 | 261 |
| Mrps10 | 237 |
| Srp68 | 157 |
| Mrps36 | 115 |
| Srpr | 63 |
| Mtif2 | 54 |
| Cars | 47 |
| Nars2 | 3 |
| Eif4h | -21 |
| Mars2 | -200 |
| Hars | -493 |
| Mrps2 | -726 |
| Mrpl39 | -826 |
| Spcs3 | -1014 |
| Ssr1 | -1076 |
| Mrpl10 | -1207 |
| N6amt1 | -1345 |
| Mrpl19 | -1448 |
| Mrrf | -1591 |
| Nars | -1824 |
| Srp72 | -1847 |
| Eif4a2 | -2044 |
| Rars2 | -2049 |
| Eif2s1 | -2149 |
| Eif4g1 | -2240 |
| Gspt1 | -2349 |
| Tars | -2423 |
| Eif4b | -2682 |
| Aars2 | -2890 |
| Mars1 | -3089 |
| Rars | -3143 |
| Mrpl44 | -3183 |
| Mrpl22 | -3379 |
| Sars2 | -3396 |
| Eif5 | -3724 |
| Srprb | -3751 |
| Wars | -3801 |
| Wars2 | -4133 |
| Gfm1 | -4233 |
| Eprs | -4256 |
| Mtif3 | -4363 |
| Yars | -4567 |
| Lars | -4585 |
| Gspt2 | -4765 |
| Eef1a2 | -4833 |
| Mrpl55 | -4920 |
| Farsb | -4937 |
| Eif1ax | -5164 |
| Aars | -5176 |
| Gars | -5203 |
| Etf1 | -5342 |
| Sec61a2 | -5451 |
| Dars | -5550 |
| Eif2b1 | -5626 |
| Eif3a | -5816 |
| Mrps5 | -6875 |
| Mrps31 | -7126 |
| Mrpl1 | -7669 |
| Iars | -7715 |
| Ptcd3 | -8034 |
| Sars | -8043 |
REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN
| set | REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN |
| setSize | 29 |
| pANOVA | 0.000133 |
| s.dist | -0.41 |
| p.adjustANOVA | 0.00211 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Nup107 | -8355 |
| Nup88 | -7616 |
| Nup54 | -7537 |
| Nup210 | -7482 |
| Nup205 | -7127 |
| Aaas | -7031 |
| Ndc1 | -6991 |
| Seh1l | -6781 |
| Tpr | -5951 |
| Nup153 | -5611 |
| Nup37 | -5542 |
| Nup98 | -4894 |
| Nup62 | -4679 |
| Nup35 | -4254 |
| Nupl2 | -3955 |
| Pom121 | -3928 |
| Nup133 | -3614 |
| Ranbp2 | -3595 |
| Nup188 | -3466 |
| Rae1 | -3187 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Nup107 | -8355 |
| Nup88 | -7616 |
| Nup54 | -7537 |
| Nup210 | -7482 |
| Nup205 | -7127 |
| Aaas | -7031 |
| Ndc1 | -6991 |
| Seh1l | -6781 |
| Tpr | -5951 |
| Nup153 | -5611 |
| Nup37 | -5542 |
| Nup98 | -4894 |
| Nup62 | -4679 |
| Nup35 | -4254 |
| Nupl2 | -3955 |
| Pom121 | -3928 |
| Nup133 | -3614 |
| Ranbp2 | -3595 |
| Nup188 | -3466 |
| Rae1 | -3187 |
| Nup160 | -1268 |
| Nup43 | -893 |
| Nup50 | -235 |
| Nup214 | 169 |
| Sec13 | 1308 |
| Nup85 | 2289 |
| Nup155 | 3222 |
| Nup93 | 4215 |
| Gck | 5759 |
EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS
| set | EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS |
| setSize | 31 |
| pANOVA | 8.23e-05 |
| s.dist | -0.409 |
| p.adjustANOVA | 0.00143 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Nup107 | -8355 |
| Hspa1a | -8121 |
| Nup88 | -7616 |
| Nup54 | -7537 |
| Nup210 | -7482 |
| Nup205 | -7127 |
| Aaas | -7031 |
| Ndc1 | -6991 |
| Seh1l | -6781 |
| Tpr | -5951 |
| Nup153 | -5611 |
| Nup37 | -5542 |
| Nup98 | -4894 |
| Nup62 | -4679 |
| Nup35 | -4254 |
| Nupl2 | -3955 |
| Pom121 | -3928 |
| Nup133 | -3614 |
| Ranbp2 | -3595 |
| Nup188 | -3466 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Nup107 | -8355 |
| Hspa1a | -8121 |
| Nup88 | -7616 |
| Nup54 | -7537 |
| Nup210 | -7482 |
| Nup205 | -7127 |
| Aaas | -7031 |
| Ndc1 | -6991 |
| Seh1l | -6781 |
| Tpr | -5951 |
| Nup153 | -5611 |
| Nup37 | -5542 |
| Nup98 | -4894 |
| Nup62 | -4679 |
| Nup35 | -4254 |
| Nupl2 | -3955 |
| Pom121 | -3928 |
| Nup133 | -3614 |
| Ranbp2 | -3595 |
| Nup188 | -3466 |
| Rae1 | -3187 |
| Nup160 | -1268 |
| Nup43 | -893 |
| Nup50 | -235 |
| Nup214 | 169 |
| Sec13 | 1308 |
| Xpo1 | 1947 |
| Nup85 | 2289 |
| Nup155 | 3222 |
| Nup93 | 4215 |
| Ran | 5628 |
ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM
| set | ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM |
| setSize | 12 |
| pANOVA | 0.0144 |
| s.dist | 0.408 |
| p.adjustANOVA | 0.088 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Elovl2 | 8344 |
| Acaa1a | 7597 |
| Fads2 | 7337 |
| Scp2 | 6946 |
| Elovl1 | 6662 |
| Acot8 | 6631 |
| Fads1 | 4884 |
| Abcd1 | 2304 |
| Hsd17b4 | 1888 |
| Elovl5 | 1033 |
| Acox1 | -2010 |
| Acsl1 | -7957 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Elovl2 | 8344 |
| Acaa1a | 7597 |
| Fads2 | 7337 |
| Scp2 | 6946 |
| Elovl1 | 6662 |
| Acot8 | 6631 |
| Fads1 | 4884 |
| Abcd1 | 2304 |
| Hsd17b4 | 1888 |
| Elovl5 | 1033 |
| Acox1 | -2010 |
| Acsl1 | -7957 |
ANTIGEN PROCESSING CROSS PRESENTATION
| set | ANTIGEN PROCESSING CROSS PRESENTATION |
| setSize | 97 |
| pANOVA | 4.26e-12 |
| s.dist | 0.407 |
| p.adjustANOVA | 2.79e-10 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Snap23 | 8621 |
| Cd14 | 8564 |
| Psme2 | 8167 |
| Tapbp | 8116 |
| Sec61g | 8104 |
| Rps27a | 7650 |
| Sec61b | 7616 |
| Psmb2 | 7416 |
| Uba52 | 7390 |
| Itgb5 | 7249 |
| S100a1 | 7225 |
| Psma3 | 7211 |
| Sem1 | 7197 |
| Vamp8 | 7066 |
| Cyba | 7019 |
| Vamp3 | 7011 |
| Psmd13 | 6995 |
| Cd36 | 6992 |
| Psmd3 | 6933 |
| Psmd10 | 6835 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Snap23 | 8621 |
| Cd14 | 8564 |
| Psme2 | 8167 |
| Tapbp | 8116 |
| Sec61g | 8104 |
| Rps27a | 7650 |
| Sec61b | 7616 |
| Psmb2 | 7416 |
| Uba52 | 7390 |
| Itgb5 | 7249 |
| S100a1 | 7225 |
| Psma3 | 7211 |
| Sem1 | 7197 |
| Vamp8 | 7066 |
| Cyba | 7019 |
| Vamp3 | 7011 |
| Psmd13 | 6995 |
| Cd36 | 6992 |
| Psmd3 | 6933 |
| Psmd10 | 6835 |
| Ikbkb | 6807 |
| Psmd14 | 6756 |
| Tlr2 | 6729 |
| Psmd9 | 6720 |
| Psmc5 | 6669 |
| B2m | 6647 |
| H2-Q7 | 6536 |
| Calr | 6481 |
| Myd88 | 6282 |
| Psmb7 | 6239 |
| Psmc3 | 6233 |
| Psmb4 | 6222 |
| Psmb5 | 6186 |
| Psmd8 | 6112 |
| Psma1 | 6039 |
| Mrc2 | 5958 |
| Psmc4 | 5879 |
| Psmd7 | 5877 |
| Psmb1 | 5844 |
| Hmgb1 | 5824 |
| Psmb10 | 5781 |
| Stx4a | 5761 |
| Ncf1 | 5673 |
| Psmb6 | 5649 |
| Psmb3 | 5551 |
| Chuk | 5449 |
| S100a9 | 5339 |
| H2-Q2 | 5329 |
| H2-T23 | 5215 |
| Psmd6 | 5161 |
| Ncf2 | 5067 |
| Ctsl | 4952 |
| H2-Bl | 4802 |
| H2-D1 | 4745 |
| Psma7 | 4674 |
| Psma2 | 4614 |
| Psme1 | 4564 |
| Psma6 | 4555 |
| H2-Q10 | 4365 |
| Pdia3 | 4296 |
| Itgav | 4026 |
| Psmb8 | 3669 |
| Psma5 | 3570 |
| Psmd4 | 3516 |
| Psme3 | 3265 |
| Ctss | 2955 |
| Lnpep | 2504 |
| Fcgr1 | 1944 |
| Psma4 | 1887 |
| Tap2 | 1415 |
| Psmc1 | 1380 |
| Tap1 | 1347 |
| Sec22b | 1116 |
| Psmb9 | 907 |
| Psmd11 | 828 |
| Sec61a1 | 507 |
| Psmc2 | 431 |
| Ubb | 86 |
| Ikbkg | -41 |
| Tlr4 | -99 |
| H2-M3 | -248 |
| Psmf1 | -380 |
| Psmd2 | -922 |
| Btk | -1145 |
| Psmd5 | -1283 |
| Psmd1 | -2046 |
| Cybb | -2094 |
| Psme4 | -2417 |
| Tlr6 | -2526 |
| Mrc1 | -3888 |
| Tlr1 | -4465 |
| Psmc6 | -5260 |
| Sec61a2 | -5451 |
| Tirap | -6447 |
| Ubc | -7102 |
| Psmd12 | -7851 |
| Ncf4 | -8133 |
BRANCHED CHAIN AMINO ACID CATABOLISM
| set | BRANCHED CHAIN AMINO ACID CATABOLISM |
| setSize | 21 |
| pANOVA | 0.00125 |
| s.dist | 0.407 |
| p.adjustANOVA | 0.0122 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Bcat2 | 8550 |
| Acad8 | 8469 |
| Mccc1 | 8277 |
| Acadsb | 8034 |
| Ivd | 8008 |
| Ppm1k | 6873 |
| Dbt | 6531 |
| Bckdhb | 6345 |
| Aldh6a1 | 6164 |
| Mccc2 | 5987 |
| Bckdha | 5974 |
| Hsd17b10 | 5066 |
| Echs1 | 4798 |
| Hibadh | 2479 |
| Acat1 | 1573 |
| Hibch | 1110 |
| Slc25a44 | -1726 |
| Auh | -3340 |
| Dld | -3576 |
| Bckdk | -3625 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Bcat2 | 8550 |
| Acad8 | 8469 |
| Mccc1 | 8277 |
| Acadsb | 8034 |
| Ivd | 8008 |
| Ppm1k | 6873 |
| Dbt | 6531 |
| Bckdhb | 6345 |
| Aldh6a1 | 6164 |
| Mccc2 | 5987 |
| Bckdha | 5974 |
| Hsd17b10 | 5066 |
| Echs1 | 4798 |
| Hibadh | 2479 |
| Acat1 | 1573 |
| Hibch | 1110 |
| Slc25a44 | -1726 |
| Auh | -3340 |
| Dld | -3576 |
| Bckdk | -3625 |
| Bcat1 | -5802 |
KERATAN SULFATE DEGRADATION
| set | KERATAN SULFATE DEGRADATION |
| setSize | 12 |
| pANOVA | 0.0148 |
| s.dist | 0.407 |
| p.adjustANOVA | 0.0882 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Lum | 8065 |
| Prelp | 7956 |
| Fmod | 7559 |
| Ogn | 7015 |
| Hexa | 6557 |
| Hexb | 6142 |
| Omd | 5526 |
| Galns | 5300 |
| Glb1l | 4308 |
| Gns | -2332 |
| Glb1 | -4199 |
| Acan | -8380 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Lum | 8065 |
| Prelp | 7956 |
| Fmod | 7559 |
| Ogn | 7015 |
| Hexa | 6557 |
| Hexb | 6142 |
| Omd | 5526 |
| Galns | 5300 |
| Glb1l | 4308 |
| Gns | -2332 |
| Glb1 | -4199 |
| Acan | -8380 |
METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES
| set | METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES |
| setSize | 21 |
| pANOVA | 0.00135 |
| s.dist | 0.404 |
| p.adjustANOVA | 0.0129 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Ahcy | 8530 |
| Tbxas1 | 8492 |
| Oplah | 8377 |
| Cyp7b1 | 8041 |
| Fdx1 | 7878 |
| Cyp1b1 | 7747 |
| Slc35d1 | 7660 |
| Gss | 7318 |
| Cyp2u1 | 7276 |
| Tpmt | 6210 |
| Ggt1 | 4927 |
| Maoa | 3726 |
| Fdx2 | 2439 |
| Fdxr | 1441 |
| Gclm | 1220 |
| Cyp11a1 | 180 |
| Acy1 | -422 |
| Cyp26b1 | -889 |
| Gclc | -4209 |
| Cyp27a1 | -5023 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Ahcy | 8530 |
| Tbxas1 | 8492 |
| Oplah | 8377 |
| Cyp7b1 | 8041 |
| Fdx1 | 7878 |
| Cyp1b1 | 7747 |
| Slc35d1 | 7660 |
| Gss | 7318 |
| Cyp2u1 | 7276 |
| Tpmt | 6210 |
| Ggt1 | 4927 |
| Maoa | 3726 |
| Fdx2 | 2439 |
| Fdxr | 1441 |
| Gclm | 1220 |
| Cyp11a1 | 180 |
| Acy1 | -422 |
| Cyp26b1 | -889 |
| Gclc | -4209 |
| Cyp27a1 | -5023 |
| Cyp19a1 | -5252 |
CS DS DEGRADATION
| set | CS DS DEGRADATION |
| setSize | 14 |
| pANOVA | 0.00946 |
| s.dist | 0.401 |
| p.adjustANOVA | 0.0656 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Hyal1 | 8262 |
| Vcan | 7946 |
| Bgn | 7482 |
| Dcn | 7034 |
| Hexa | 6557 |
| Hexb | 6142 |
| Hyal3 | 5321 |
| Bcan | 4929 |
| Cspg5 | 2616 |
| Ncan | 2086 |
| Arsb | 353 |
| Idua | 168 |
| Ids | -3809 |
| Cspg4 | -5036 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Hyal1 | 8262 |
| Vcan | 7946 |
| Bgn | 7482 |
| Dcn | 7034 |
| Hexa | 6557 |
| Hexb | 6142 |
| Hyal3 | 5321 |
| Bcan | 4929 |
| Cspg5 | 2616 |
| Ncan | 2086 |
| Arsb | 353 |
| Idua | 168 |
| Ids | -3809 |
| Cspg4 | -5036 |
ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES
| set | ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES |
| setSize | 10 |
| pANOVA | 0.0305 |
| s.dist | -0.395 |
| p.adjustANOVA | 0.147 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Angptl4 | -8114 |
| Lpl | -8026 |
| Pcsk5 | -7522 |
| Mbtps2 | -7036 |
| Pcsk6 | -5127 |
| Mbtps1 | -3472 |
| Furin | -1304 |
| Creb3l3 | -965 |
| Lmf2 | 4574 |
| Lmf1 | 4762 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Angptl4 | -8114 |
| Lpl | -8026 |
| Pcsk5 | -7522 |
| Mbtps2 | -7036 |
| Pcsk6 | -5127 |
| Mbtps1 | -3472 |
| Furin | -1304 |
| Creb3l3 | -965 |
| Lmf2 | 4574 |
| Lmf1 | 4762 |
PHASE 0 RAPID DEPOLARISATION
| set | PHASE 0 RAPID DEPOLARISATION |
| setSize | 30 |
| pANOVA | 0.000221 |
| s.dist | -0.39 |
| p.adjustANOVA | 0.00303 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Camk2g | -7823 |
| Fgf13 | -7684 |
| Scn3b | -7487 |
| Camk2b | -7200 |
| Cacng7 | -6977 |
| Cacnb1 | -6880 |
| Cacnb2 | -6714 |
| Fgf14 | -6650 |
| Cacng6 | -6387 |
| Scn1b | -6277 |
| Scn5a | -4650 |
| Fgf12 | -4528 |
| Camk2d | -4044 |
| Scn4b | -3697 |
| Scn2b | -3575 |
| Scn8a | -3452 |
| Cacna2d2 | -2570 |
| Cacng4 | -2529 |
| Scn1a | -2352 |
| Cacng8 | -2234 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Camk2g | -7823 |
| Fgf13 | -7684 |
| Scn3b | -7487 |
| Camk2b | -7200 |
| Cacng7 | -6977 |
| Cacnb1 | -6880 |
| Cacnb2 | -6714 |
| Fgf14 | -6650 |
| Cacng6 | -6387 |
| Scn1b | -6277 |
| Scn5a | -4650 |
| Fgf12 | -4528 |
| Camk2d | -4044 |
| Scn4b | -3697 |
| Scn2b | -3575 |
| Scn8a | -3452 |
| Cacna2d2 | -2570 |
| Cacng4 | -2529 |
| Scn1a | -2352 |
| Cacng8 | -2234 |
| Scn2a | -1986 |
| Scn3a | -865 |
| Camk2a | -717 |
| Rangrf | -502 |
| Fgf11 | -233 |
| Cacna1c | 276 |
| Scn11a | 933 |
| Calm1 | 1522 |
| Scn7a | 4303 |
| Scn9a | 5842 |
G PROTEIN ACTIVATION
| set | G PROTEIN ACTIVATION |
| setSize | 22 |
| pANOVA | 0.00171 |
| s.dist | 0.386 |
| p.adjustANOVA | 0.0157 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Pdyn | 8489 |
| Gng5 | 8162 |
| Pomc | 7939 |
| Gng12 | 7725 |
| Gng10 | 7667 |
| Gngt2 | 6406 |
| Gnb4 | 6272 |
| Gna11 | 5847 |
| Gng13 | 5779 |
| Gng8 | 5475 |
| Gng11 | 4553 |
| Gng3 | 3542 |
| Gnb2 | 3212 |
| Gna15 | 3178 |
| Gnb1 | 2606 |
| Gng7 | 2311 |
| Gng4 | -105 |
| Oprm1 | -472 |
| Gna14 | -747 |
| Gnaq | -1547 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Pdyn | 8489 |
| Gng5 | 8162 |
| Pomc | 7939 |
| Gng12 | 7725 |
| Gng10 | 7667 |
| Gngt2 | 6406 |
| Gnb4 | 6272 |
| Gna11 | 5847 |
| Gng13 | 5779 |
| Gng8 | 5475 |
| Gng11 | 4553 |
| Gng3 | 3542 |
| Gnb2 | 3212 |
| Gna15 | 3178 |
| Gnb1 | 2606 |
| Gng7 | 2311 |
| Gng4 | -105 |
| Oprm1 | -472 |
| Gna14 | -747 |
| Gnaq | -1547 |
| Gnb5 | -4408 |
| Gng2 | -5942 |
NUCLEAR PORE COMPLEX NPC DISASSEMBLY
| set | NUCLEAR PORE COMPLEX NPC DISASSEMBLY |
| setSize | 32 |
| pANOVA | 0.000158 |
| s.dist | -0.386 |
| p.adjustANOVA | 0.00241 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Nup107 | -8355 |
| Nup88 | -7616 |
| Nek6 | -7541 |
| Nup54 | -7537 |
| Nup210 | -7482 |
| Nup205 | -7127 |
| Aaas | -7031 |
| Ndc1 | -6991 |
| Seh1l | -6781 |
| Tpr | -5951 |
| Nup153 | -5611 |
| Nup37 | -5542 |
| Nup98 | -4894 |
| Nup62 | -4679 |
| Nup35 | -4254 |
| Nupl2 | -3955 |
| Pom121 | -3928 |
| Nup133 | -3614 |
| Ranbp2 | -3595 |
| Nup188 | -3466 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Nup107 | -8355 |
| Nup88 | -7616 |
| Nek6 | -7541 |
| Nup54 | -7537 |
| Nup210 | -7482 |
| Nup205 | -7127 |
| Aaas | -7031 |
| Ndc1 | -6991 |
| Seh1l | -6781 |
| Tpr | -5951 |
| Nup153 | -5611 |
| Nup37 | -5542 |
| Nup98 | -4894 |
| Nup62 | -4679 |
| Nup35 | -4254 |
| Nupl2 | -3955 |
| Pom121 | -3928 |
| Nup133 | -3614 |
| Ranbp2 | -3595 |
| Nup188 | -3466 |
| Rae1 | -3187 |
| Nek9 | -2632 |
| Nup160 | -1268 |
| Nup43 | -893 |
| Nup50 | -235 |
| Nup214 | 169 |
| Sec13 | 1308 |
| Nup85 | 2289 |
| Nup155 | 3222 |
| Nup93 | 4215 |
| Nek7 | 5931 |
| Ccnb2 | 6558 |
RIP MEDIATED NFKB ACTIVATION VIA ZBP1
| set | RIP MEDIATED NFKB ACTIVATION VIA ZBP1 |
| setSize | 15 |
| pANOVA | 0.00987 |
| s.dist | 0.385 |
| p.adjustANOVA | 0.0676 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Nfkb2 | 8458 |
| Nfkbib | 7644 |
| Nkiras2 | 7204 |
| Ikbkb | 6807 |
| Myd88 | 6282 |
| Ripk1 | 6256 |
| Chuk | 5449 |
| Ticam1 | 4370 |
| Rela | 3019 |
| Nfkbia | 1048 |
| Nkiras1 | 1032 |
| Nfkb1 | 555 |
| Ikbkg | -41 |
| Tlr3 | -1594 |
| Dhx9 | -4881 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Nfkb2 | 8458 |
| Nfkbib | 7644 |
| Nkiras2 | 7204 |
| Ikbkb | 6807 |
| Myd88 | 6282 |
| Ripk1 | 6256 |
| Chuk | 5449 |
| Ticam1 | 4370 |
| Rela | 3019 |
| Nfkbia | 1048 |
| Nkiras1 | 1032 |
| Nfkb1 | 555 |
| Ikbkg | -41 |
| Tlr3 | -1594 |
| Dhx9 | -4881 |
THROMBOXANE SIGNALLING THROUGH TP RECEPTOR
| set | THROMBOXANE SIGNALLING THROUGH TP RECEPTOR |
| setSize | 22 |
| pANOVA | 0.00196 |
| s.dist | 0.381 |
| p.adjustANOVA | 0.0175 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Gng5 | 8162 |
| Gng12 | 7725 |
| Gng10 | 7667 |
| Gngt2 | 6406 |
| Aamp | 6329 |
| Gnb4 | 6272 |
| Gna11 | 5847 |
| Gng13 | 5779 |
| Tbxa2r | 5651 |
| Gng8 | 5475 |
| Gng11 | 4553 |
| Gng3 | 3542 |
| Gnb2 | 3212 |
| Gna15 | 3178 |
| Gna13 | 3049 |
| Gnb1 | 2606 |
| Gng7 | 2311 |
| Gng4 | -105 |
| Gna14 | -747 |
| Gnaq | -1547 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Gng5 | 8162 |
| Gng12 | 7725 |
| Gng10 | 7667 |
| Gngt2 | 6406 |
| Aamp | 6329 |
| Gnb4 | 6272 |
| Gna11 | 5847 |
| Gng13 | 5779 |
| Tbxa2r | 5651 |
| Gng8 | 5475 |
| Gng11 | 4553 |
| Gng3 | 3542 |
| Gnb2 | 3212 |
| Gna15 | 3178 |
| Gna13 | 3049 |
| Gnb1 | 2606 |
| Gng7 | 2311 |
| Gng4 | -105 |
| Gna14 | -747 |
| Gnaq | -1547 |
| Gnb5 | -4408 |
| Gng2 | -5942 |
CRISTAE FORMATION
| set | CRISTAE FORMATION |
| setSize | 31 |
| pANOVA | 0.00024 |
| s.dist | 0.381 |
| p.adjustANOVA | 0.00321 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Atp5g2 | 8457 |
| mt-Atp8 | 8090 |
| Atp5e | 7419 |
| Micos13 | 7279 |
| Atp5k | 7191 |
| Chchd6 | 6613 |
| Atp5l | 6507 |
| mt-Atp6 | 6401 |
| Atp5h | 6283 |
| Atp5g3 | 6018 |
| Mtx2 | 5698 |
| Atp5d | 5331 |
| Mtx1 | 5031 |
| Chchd3 | 5009 |
| Micos10 | 4685 |
| Atp5j2 | 3902 |
| Atp5j | 3861 |
| Samm50 | 3859 |
| Atp5c1 | 3539 |
| Atp5a1 | 3507 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Atp5g2 | 8457 |
| mt-Atp8 | 8090 |
| Atp5e | 7419 |
| Micos13 | 7279 |
| Atp5k | 7191 |
| Chchd6 | 6613 |
| Atp5l | 6507 |
| mt-Atp6 | 6401 |
| Atp5h | 6283 |
| Atp5g3 | 6018 |
| Mtx2 | 5698 |
| Atp5d | 5331 |
| Mtx1 | 5031 |
| Chchd3 | 5009 |
| Micos10 | 4685 |
| Atp5j2 | 3902 |
| Atp5j | 3861 |
| Samm50 | 3859 |
| Atp5c1 | 3539 |
| Atp5a1 | 3507 |
| Atp5g1 | 3376 |
| Atp5b | 2773 |
| Dmac2l | 1976 |
| Immt | 1067 |
| Tmem11 | 983 |
| Atp5pb | 826 |
| Atp5o | 98 |
| Apoo | -1116 |
| Hspa9 | -5045 |
| Dnajc11 | -6796 |
| Apool | -7223 |
SUMOYLATION OF SUMOYLATION PROTEINS
| set | SUMOYLATION OF SUMOYLATION PROTEINS |
| setSize | 33 |
| pANOVA | 0.000167 |
| s.dist | -0.379 |
| p.adjustANOVA | 0.00253 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Nup107 | -8355 |
| Topors | -8004 |
| Nup88 | -7616 |
| Nup54 | -7537 |
| Nup210 | -7482 |
| Nup205 | -7127 |
| Aaas | -7031 |
| Ndc1 | -6991 |
| Seh1l | -6781 |
| Tpr | -5951 |
| Nup153 | -5611 |
| Nup37 | -5542 |
| Nup98 | -4894 |
| Nup62 | -4679 |
| Nup35 | -4254 |
| Nupl2 | -3955 |
| Pom121 | -3928 |
| Ube2i | -3852 |
| Nup133 | -3614 |
| Ranbp2 | -3595 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Nup107 | -8355 |
| Topors | -8004 |
| Nup88 | -7616 |
| Nup54 | -7537 |
| Nup210 | -7482 |
| Nup205 | -7127 |
| Aaas | -7031 |
| Ndc1 | -6991 |
| Seh1l | -6781 |
| Tpr | -5951 |
| Nup153 | -5611 |
| Nup37 | -5542 |
| Nup98 | -4894 |
| Nup62 | -4679 |
| Nup35 | -4254 |
| Nupl2 | -3955 |
| Pom121 | -3928 |
| Ube2i | -3852 |
| Nup133 | -3614 |
| Ranbp2 | -3595 |
| Nup188 | -3466 |
| Rae1 | -3187 |
| Nup160 | -1268 |
| Nup43 | -893 |
| Nup50 | -235 |
| Nup214 | 169 |
| Sec13 | 1308 |
| Nup85 | 2289 |
| Sumo2 | 2585 |
| Nup155 | 3222 |
| Nup93 | 4215 |
| Pias4 | 5089 |
| Sumo1 | 5435 |
ASPARTATE AND ASPARAGINE METABOLISM
| set | ASPARTATE AND ASPARAGINE METABOLISM |
| setSize | 10 |
| pANOVA | 0.0382 |
| s.dist | -0.379 |
| p.adjustANOVA | 0.169 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Got1 | -7212 |
| Nat8l | -6765 |
| Asns | -6356 |
| Got2 | -5868 |
| Aspa | -5695 |
| Slc25a12 | -4391 |
| Aspg | -3294 |
| Folh1 | -222 |
| Naalad2 | 1550 |
| Slc25a13 | 7443 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Got1 | -7212 |
| Nat8l | -6765 |
| Asns | -6356 |
| Got2 | -5868 |
| Aspa | -5695 |
| Slc25a12 | -4391 |
| Aspg | -3294 |
| Folh1 | -222 |
| Naalad2 | 1550 |
| Slc25a13 | 7443 |
Here is the session info with all the versions of packages used.
sessionInfo()## R version 4.4.0 (2024-04-24)
## Platform: x86_64-pc-linux-gnu
## Running under: Ubuntu 22.04.4 LTS
##
## Matrix products: default
## BLAS: /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.10.0
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.10.0
##
## locale:
## [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
## [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8
## [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
## [7] LC_PAPER=en_US.UTF-8 LC_NAME=C
## [9] LC_ADDRESS=C LC_TELEPHONE=C
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
##
## time zone: Australia/Melbourne
## tzcode source: system (glibc)
##
## attached base packages:
## [1] stats4 stats graphics grDevices utils datasets methods
## [8] base
##
## other attached packages:
## [1] GGally_2.2.1 ggplot2_3.5.1
## [3] gtools_3.9.5 tibble_3.2.1
## [5] dplyr_1.1.4 echarts4r_0.4.5
## [7] beeswarm_0.4.0 pkgload_1.3.4
## [9] vioplot_0.4.0 sm_2.2-6.0
## [11] kableExtra_1.4.0 topconfects_1.20.0
## [13] limma_3.60.0 eulerr_7.0.2
## [15] mitch_1.16.0 MASS_7.3-60.2
## [17] fgsea_1.30.0 gplots_3.1.3.1
## [19] DESeq2_1.44.0 SummarizedExperiment_1.34.0
## [21] Biobase_2.64.0 MatrixGenerics_1.16.0
## [23] matrixStats_1.3.0 GenomicRanges_1.56.0
## [25] GenomeInfoDb_1.40.0 IRanges_2.38.0
## [27] S4Vectors_0.42.0 BiocGenerics_0.50.0
## [29] reshape2_1.4.4 zoo_1.8-12
##
## loaded via a namespace (and not attached):
## [1] bitops_1.0-7 gridExtra_2.3 rlang_1.1.4
## [4] magrittr_2.0.3 compiler_4.4.0 polylabelr_0.2.0
## [7] systemfonts_1.1.0 vctrs_0.6.5 stringr_1.5.1
## [10] pkgconfig_2.0.3 crayon_1.5.2 fastmap_1.2.0
## [13] XVector_0.44.0 caTools_1.18.2 utf8_1.2.4
## [16] promises_1.3.0 rmarkdown_2.27 UCSC.utils_1.0.0
## [19] purrr_1.0.2 xfun_0.44 zlibbioc_1.50.0
## [22] cachem_1.1.0 jsonlite_1.8.8 highr_0.11
## [25] later_1.3.2 DelayedArray_0.30.1 BiocParallel_1.38.0
## [28] parallel_4.4.0 R6_2.5.1 bslib_0.7.0
## [31] stringi_1.8.4 RColorBrewer_1.1-3 jquerylib_0.1.4
## [34] Rcpp_1.0.12 assertthat_0.2.1 knitr_1.47
## [37] httpuv_1.6.15 Matrix_1.7-0 tidyselect_1.2.1
## [40] rstudioapi_0.16.0 abind_1.4-5 yaml_2.3.8
## [43] codetools_0.2-20 lattice_0.22-6 plyr_1.8.9
## [46] withr_3.0.0 shiny_1.8.1.1 evaluate_0.23
## [49] polyclip_1.10-6 ggstats_0.6.0 xml2_1.3.6
## [52] pillar_1.9.0 KernSmooth_2.23-24 generics_0.1.3
## [55] munsell_0.5.1 scales_1.3.0 xtable_1.8-4
## [58] glue_1.7.0 tools_4.4.0 data.table_1.15.4
## [61] locfit_1.5-9.9 fastmatch_1.1-4 cowplot_1.1.3
## [64] grid_4.4.0 tidyr_1.3.1 colorspace_2.1-0
## [67] GenomeInfoDbData_1.2.12 cli_3.6.2 fansi_1.0.6
## [70] S4Arrays_1.4.0 viridisLite_0.4.2 svglite_2.1.3
## [73] gtable_0.3.5 sass_0.4.9 digest_0.6.35
## [76] SparseArray_1.4.3 htmlwidgets_1.6.4 htmltools_0.5.8.1
## [79] lifecycle_1.0.4 httr_1.4.7 statmod_1.5.0
## [82] mime_0.12END of report