Mitch Report
Antony Kaspi & Mark Ziemann
date generated: 2024-06-05
Background
Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch
Input profiles
Here is the first few lines of the input profile.
| x | |
|---|---|
| 0610009B22Rik | 1.8312366 |
| 0610009E02Rik | -0.1037028 |
| 0610009L18Rik | -0.0756377 |
| 0610010K14Rik | 0.4176706 |
| 0610012G03Rik | 0.0087096 |
| 0610030E20Rik | -1.6095238 |
Here are some metrics about the input data profile:
| Profile metrics | |
|---|---|
| num_genesets | 1604 |
| num_genes_in_profile | 16611 |
| duplicated_genes_present | 0 |
| num_profile_genes_in_sets | 8254 |
| num_profile_genes_not_in_sets | 8357 |
Here is a plot of the input profiles. Note the dynamic ranges.
Here is the contour plot of the profile including all detected genes.
Input genesets
Here are some metrics about the gene sets used:
GMT file of genesets:| Gene sets metrics | |
|---|---|
| num_genesets | 1604 |
| num_genesets_excluded | 437 |
| num_genesets_included | 1167 |
Differential pathway expression
Interactive enrichment scatterplot
Significance is calculated by -log10(p-value). All points shown are FDR<0.05.
Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.
Results table
Top N= 50 gene sets| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | 11 | 1.76e-04 | 0.653 | 1.65e-03 |
| NUCLEOTIDE LIKE PURINERGIC RECEPTORS | 13 | 5.32e-04 | 0.555 | 4.34e-03 |
| ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 | 19 | 4.05e-05 | 0.544 | 5.13e-04 |
| ASPARTATE AND ASPARAGINE METABOLISM | 10 | 3.02e-03 | 0.542 | 1.72e-02 |
| COMPLEX I BIOGENESIS | 56 | 4.15e-12 | 0.535 | 2.85e-10 |
| SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | 20 | 3.49e-05 | 0.535 | 4.58e-04 |
| TRIGLYCERIDE CATABOLISM | 14 | 6.66e-04 | 0.525 | 5.27e-03 |
| PINK1 PRKN MEDIATED MITOPHAGY | 22 | 2.43e-05 | 0.520 | 3.33e-04 |
| FRS MEDIATED FGFR4 SIGNALING | 12 | 1.91e-03 | 0.518 | 1.21e-02 |
| SHC MEDIATED CASCADE FGFR4 | 10 | 4.72e-03 | 0.516 | 2.43e-02 |
| EUKARYOTIC TRANSLATION ELONGATION | 87 | 1.03e-16 | 0.515 | 1.10e-14 |
| CRMPS IN SEMA3A SIGNALING | 16 | 3.86e-04 | -0.513 | 3.31e-03 |
| RESPIRATORY ELECTRON TRANSPORT | 102 | 4.40e-19 | 0.511 | 8.56e-17 |
| PI 3K CASCADE FGFR4 | 10 | 5.33e-03 | 0.509 | 2.65e-02 |
| RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | 125 | 2.09e-22 | 0.504 | 4.88e-20 |
| PLATELET SENSITIZATION BY LDL | 15 | 7.63e-04 | 0.502 | 5.74e-03 |
| FRS MEDIATED FGFR3 SIGNALING | 14 | 1.20e-03 | 0.500 | 8.19e-03 |
| SIGNALING BY FGFR3 FUSIONS IN CANCER | 10 | 6.27e-03 | 0.499 | 3.02e-02 |
| SHC MEDIATED CASCADE FGFR3 | 12 | 2.95e-03 | 0.496 | 1.68e-02 |
| CITRIC ACID CYCLE TCA CYCLE | 22 | 5.73e-05 | 0.496 | 6.62e-04 |
| SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES | 29 | 4.04e-06 | 0.494 | 8.43e-05 |
| BLOOD GROUP SYSTEMS BIOSYNTHESIS | 13 | 2.05e-03 | 0.494 | 1.28e-02 |
| SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | 106 | 2.70e-18 | 0.490 | 3.15e-16 |
| PI 3K CASCADE FGFR3 | 12 | 3.30e-03 | 0.490 | 1.82e-02 |
| TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS | 15 | 1.12e-03 | 0.486 | 7.81e-03 |
| RHOBTB3 ATPASE CYCLE | 10 | 8.04e-03 | 0.484 | 3.69e-02 |
| FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | 18 | 3.83e-04 | 0.483 | 3.31e-03 |
| ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | 59 | 1.88e-10 | 0.479 | 1.00e-08 |
| ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES | 10 | 9.07e-03 | 0.477 | 4.10e-02 |
| FATTY ACYL COA BIOSYNTHESIS | 32 | 3.13e-06 | 0.476 | 6.76e-05 |
| FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES | 17 | 7.14e-04 | 0.474 | 5.51e-03 |
| EUKARYOTIC TRANSLATION INITIATION | 114 | 2.27e-18 | 0.474 | 3.10e-16 |
| PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | 16 | 1.04e-03 | 0.473 | 7.48e-03 |
| ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM | 12 | 4.70e-03 | 0.471 | 2.43e-02 |
| RAS PROCESSING | 23 | 9.41e-05 | 0.470 | 9.83e-04 |
| GLYCOGEN SYNTHESIS | 14 | 2.41e-03 | 0.468 | 1.44e-02 |
| THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT | 172 | 3.22e-26 | 0.468 | 1.25e-23 |
| RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY | 94 | 4.86e-15 | 0.467 | 4.36e-13 |
| METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION | 15 | 1.96e-03 | 0.462 | 1.24e-02 |
| G BETA GAMMA SIGNALLING THROUGH CDC42 | 18 | 7.73e-04 | 0.458 | 5.74e-03 |
| METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS | 10 | 1.23e-02 | 0.457 | 5.22e-02 |
| GLYCOGEN STORAGE DISEASES | 12 | 6.45e-03 | 0.454 | 3.10e-02 |
| CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT | 20 | 4.40e-04 | 0.454 | 3.67e-03 |
| PROTEIN METHYLATION | 17 | 1.24e-03 | 0.452 | 8.36e-03 |
| SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | 12 | 6.92e-03 | 0.450 | 3.25e-02 |
| ENOS ACTIVATION | 11 | 1.00e-02 | 0.448 | 4.43e-02 |
| DARPP 32 EVENTS | 23 | 2.27e-04 | 0.444 | 2.07e-03 |
| MITOPHAGY | 29 | 5.72e-05 | 0.432 | 6.62e-04 |
| CRISTAE FORMATION | 31 | 3.31e-05 | 0.431 | 4.44e-04 |
| SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX | 13 | 7.18e-03 | 0.431 | 3.34e-02 |
Results (complete table)
Click HERE to show results for all gene sets
| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | 11 | 1.76e-04 | 6.53e-01 | 1.65e-03 |
| NUCLEOTIDE LIKE PURINERGIC RECEPTORS | 13 | 5.32e-04 | 5.55e-01 | 4.34e-03 |
| ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 | 19 | 4.05e-05 | 5.44e-01 | 5.13e-04 |
| ASPARTATE AND ASPARAGINE METABOLISM | 10 | 3.02e-03 | 5.42e-01 | 1.72e-02 |
| COMPLEX I BIOGENESIS | 56 | 4.15e-12 | 5.35e-01 | 2.85e-10 |
| SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | 20 | 3.49e-05 | 5.35e-01 | 4.58e-04 |
| TRIGLYCERIDE CATABOLISM | 14 | 6.66e-04 | 5.25e-01 | 5.27e-03 |
| PINK1 PRKN MEDIATED MITOPHAGY | 22 | 2.43e-05 | 5.20e-01 | 3.33e-04 |
| FRS MEDIATED FGFR4 SIGNALING | 12 | 1.91e-03 | 5.18e-01 | 1.21e-02 |
| SHC MEDIATED CASCADE FGFR4 | 10 | 4.72e-03 | 5.16e-01 | 2.43e-02 |
| EUKARYOTIC TRANSLATION ELONGATION | 87 | 1.03e-16 | 5.15e-01 | 1.10e-14 |
| CRMPS IN SEMA3A SIGNALING | 16 | 3.86e-04 | -5.13e-01 | 3.31e-03 |
| RESPIRATORY ELECTRON TRANSPORT | 102 | 4.40e-19 | 5.11e-01 | 8.56e-17 |
| PI 3K CASCADE FGFR4 | 10 | 5.33e-03 | 5.09e-01 | 2.65e-02 |
| RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | 125 | 2.09e-22 | 5.04e-01 | 4.88e-20 |
| PLATELET SENSITIZATION BY LDL | 15 | 7.63e-04 | 5.02e-01 | 5.74e-03 |
| FRS MEDIATED FGFR3 SIGNALING | 14 | 1.20e-03 | 5.00e-01 | 8.19e-03 |
| SIGNALING BY FGFR3 FUSIONS IN CANCER | 10 | 6.27e-03 | 4.99e-01 | 3.02e-02 |
| SHC MEDIATED CASCADE FGFR3 | 12 | 2.95e-03 | 4.96e-01 | 1.68e-02 |
| CITRIC ACID CYCLE TCA CYCLE | 22 | 5.73e-05 | 4.96e-01 | 6.62e-04 |
| SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES | 29 | 4.04e-06 | 4.94e-01 | 8.43e-05 |
| BLOOD GROUP SYSTEMS BIOSYNTHESIS | 13 | 2.05e-03 | 4.94e-01 | 1.28e-02 |
| SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | 106 | 2.70e-18 | 4.90e-01 | 3.15e-16 |
| PI 3K CASCADE FGFR3 | 12 | 3.30e-03 | 4.90e-01 | 1.82e-02 |
| TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS | 15 | 1.12e-03 | 4.86e-01 | 7.81e-03 |
| RHOBTB3 ATPASE CYCLE | 10 | 8.04e-03 | 4.84e-01 | 3.69e-02 |
| FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | 18 | 3.83e-04 | 4.83e-01 | 3.31e-03 |
| ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | 59 | 1.88e-10 | 4.79e-01 | 1.00e-08 |
| ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES | 10 | 9.07e-03 | 4.77e-01 | 4.10e-02 |
| FATTY ACYL COA BIOSYNTHESIS | 32 | 3.13e-06 | 4.76e-01 | 6.76e-05 |
| FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES | 17 | 7.14e-04 | 4.74e-01 | 5.51e-03 |
| EUKARYOTIC TRANSLATION INITIATION | 114 | 2.27e-18 | 4.74e-01 | 3.10e-16 |
| PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | 16 | 1.04e-03 | 4.73e-01 | 7.48e-03 |
| ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM | 12 | 4.70e-03 | 4.71e-01 | 2.43e-02 |
| RAS PROCESSING | 23 | 9.41e-05 | 4.70e-01 | 9.83e-04 |
| GLYCOGEN SYNTHESIS | 14 | 2.41e-03 | 4.68e-01 | 1.44e-02 |
| THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT | 172 | 3.22e-26 | 4.68e-01 | 1.25e-23 |
| RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY | 94 | 4.86e-15 | 4.67e-01 | 4.36e-13 |
| METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION | 15 | 1.96e-03 | 4.62e-01 | 1.24e-02 |
| G BETA GAMMA SIGNALLING THROUGH CDC42 | 18 | 7.73e-04 | 4.58e-01 | 5.74e-03 |
| METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS | 10 | 1.23e-02 | 4.57e-01 | 5.22e-02 |
| GLYCOGEN STORAGE DISEASES | 12 | 6.45e-03 | 4.54e-01 | 3.10e-02 |
| CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT | 20 | 4.40e-04 | 4.54e-01 | 3.67e-03 |
| PROTEIN METHYLATION | 17 | 1.24e-03 | 4.52e-01 | 8.36e-03 |
| SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | 12 | 6.92e-03 | 4.50e-01 | 3.25e-02 |
| ENOS ACTIVATION | 11 | 1.00e-02 | 4.48e-01 | 4.43e-02 |
| DARPP 32 EVENTS | 23 | 2.27e-04 | 4.44e-01 | 2.07e-03 |
| MITOPHAGY | 29 | 5.72e-05 | 4.32e-01 | 6.62e-04 |
| CRISTAE FORMATION | 31 | 3.31e-05 | 4.31e-01 | 4.44e-04 |
| SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX | 13 | 7.18e-03 | 4.31e-01 | 3.34e-02 |
| CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION | 11 | 1.49e-02 | 4.24e-01 | 6.11e-02 |
| PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | 12 | 1.10e-02 | 4.24e-01 | 4.74e-02 |
| SIGNAL AMPLIFICATION | 30 | 6.35e-05 | 4.22e-01 | 7.19e-04 |
| SELENOAMINO ACID METABOLISM | 107 | 8.49e-14 | 4.18e-01 | 6.60e-12 |
| TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX | 12 | 1.35e-02 | 4.12e-01 | 5.65e-02 |
| THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | 22 | 8.29e-04 | 4.12e-01 | 6.09e-03 |
| BRANCHED CHAIN AMINO ACID CATABOLISM | 21 | 1.10e-03 | 4.11e-01 | 7.77e-03 |
| DETOXIFICATION OF REACTIVE OXYGEN SPECIES | 31 | 7.77e-05 | 4.10e-01 | 8.32e-04 |
| CTLA4 INHIBITORY SIGNALING | 19 | 2.03e-03 | 4.09e-01 | 1.27e-02 |
| CD28 DEPENDENT VAV1 PATHWAY | 10 | 2.57e-02 | 4.07e-01 | 8.97e-02 |
| ER QUALITY CONTROL COMPARTMENT ERQC | 21 | 1.26e-03 | 4.07e-01 | 8.40e-03 |
| CALNEXIN CALRETICULIN CYCLE | 26 | 3.49e-04 | 4.05e-01 | 3.07e-03 |
| ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 | 10 | 2.66e-02 | 4.05e-01 | 9.18e-02 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 | 17 | 3.94e-03 | 4.04e-01 | 2.09e-02 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 | 19 | 2.37e-03 | 4.03e-01 | 1.42e-02 |
| DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS | 59 | 9.66e-08 | 4.01e-01 | 3.22e-06 |
| METABOLISM OF POLYAMINES | 57 | 1.86e-07 | 3.99e-01 | 5.56e-06 |
| SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS | 15 | 7.51e-03 | 3.99e-01 | 3.48e-02 |
| INFECTION WITH MYCOBACTERIUM TUBERCULOSIS | 24 | 7.32e-04 | 3.98e-01 | 5.58e-03 |
| GAP JUNCTION DEGRADATION | 11 | 2.44e-02 | 3.92e-01 | 8.74e-02 |
| PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | 51 | 1.30e-06 | 3.92e-01 | 3.17e-05 |
| COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING | 35 | 6.33e-05 | 3.91e-01 | 7.19e-04 |
| COMPLEMENT CASCADE | 22 | 1.52e-03 | 3.91e-01 | 9.93e-03 |
| TRP CHANNELS | 19 | 3.29e-03 | -3.90e-01 | 1.82e-02 |
| GLUTATHIONE CONJUGATION | 29 | 2.87e-04 | 3.89e-01 | 2.57e-03 |
| GLYCOGEN METABOLISM | 25 | 7.71e-04 | 3.89e-01 | 5.74e-03 |
| CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | 46 | 5.33e-06 | 3.88e-01 | 9.58e-05 |
| REGULATION OF RUNX1 EXPRESSION AND ACTIVITY | 17 | 5.83e-03 | -3.86e-01 | 2.83e-02 |
| GLUCONEOGENESIS | 27 | 5.24e-04 | 3.86e-01 | 4.31e-03 |
| GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION | 24 | 1.12e-03 | 3.84e-01 | 7.81e-03 |
| NEGATIVE REGULATION OF NOTCH4 SIGNALING | 54 | 1.28e-06 | 3.81e-01 | 3.17e-05 |
| N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | 35 | 9.94e-05 | 3.80e-01 | 1.03e-03 |
| SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | 13 | 1.77e-02 | 3.80e-01 | 6.97e-02 |
| TRANSLATION | 286 | 2.27e-28 | 3.80e-01 | 1.33e-25 |
| MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS | 13 | 1.89e-02 | 3.76e-01 | 7.30e-02 |
| MITOCHONDRIAL TRANSLATION | 93 | 4.83e-10 | 3.74e-01 | 2.25e-08 |
| NONSENSE MEDIATED DECAY NMD | 109 | 2.09e-11 | 3.72e-01 | 1.28e-09 |
| METABOLISM OF AMINO ACIDS AND DERIVATIVES | 307 | 5.90e-29 | 3.71e-01 | 6.88e-26 |
| TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | 16 | 1.03e-02 | 3.71e-01 | 4.50e-02 |
| REGULATION OF EXPRESSION OF SLITS AND ROBOS | 160 | 6.87e-16 | 3.70e-01 | 6.68e-14 |
| METHYLATION | 11 | 3.49e-02 | 3.67e-01 | 1.11e-01 |
| REGULATION OF RUNX3 EXPRESSION AND ACTIVITY | 53 | 3.80e-06 | 3.67e-01 | 8.06e-05 |
| COMMON PATHWAY OF FIBRIN CLOT FORMATION | 11 | 3.54e-02 | 3.66e-01 | 1.11e-01 |
| AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA | 53 | 4.28e-06 | 3.65e-01 | 8.62e-05 |
| INSULIN RECEPTOR RECYCLING | 20 | 4.83e-03 | 3.64e-01 | 2.45e-02 |
| ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 | 23 | 2.52e-03 | 3.64e-01 | 1.49e-02 |
| ERYTHROPOIETIN ACTIVATES RAS | 13 | 2.33e-02 | 3.63e-01 | 8.48e-02 |
| DEGRADATION OF GLI1 BY THE PROTEASOME | 57 | 2.27e-06 | 3.62e-01 | 5.08e-05 |
| REGULATION OF HMOX1 EXPRESSION AND ACTIVITY | 63 | 8.77e-07 | 3.58e-01 | 2.44e-05 |
| FGFR2 LIGAND BINDING AND ACTIVATION | 12 | 3.18e-02 | 3.58e-01 | 1.03e-01 |
| JOSEPHIN DOMAIN DUBS | 11 | 4.01e-02 | 3.57e-01 | 1.23e-01 |
| CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 | 11 | 4.04e-02 | 3.57e-01 | 1.23e-01 |
| PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES | 13 | 2.59e-02 | 3.57e-01 | 9.02e-02 |
| DEGRADATION OF CYSTEINE AND HOMOCYSTEINE | 12 | 3.26e-02 | 3.56e-01 | 1.05e-01 |
| HEDGEHOG LIGAND BIOGENESIS | 61 | 1.53e-06 | 3.56e-01 | 3.57e-05 |
| TRIGLYCERIDE METABOLISM | 22 | 3.86e-03 | 3.56e-01 | 2.06e-02 |
| ATF6 ATF6 ALPHA ACTIVATES CHAPERONES | 12 | 3.34e-02 | 3.55e-01 | 1.07e-01 |
| DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | 78 | 6.82e-08 | 3.53e-01 | 2.57e-06 |
| G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | 23 | 3.49e-03 | 3.52e-01 | 1.90e-02 |
| FRS MEDIATED FGFR2 SIGNALING | 18 | 1.01e-02 | 3.50e-01 | 4.45e-02 |
| SUPPRESSION OF PHAGOSOMAL MATURATION | 12 | 3.57e-02 | 3.50e-01 | 1.11e-01 |
| IRON UPTAKE AND TRANSPORT | 52 | 1.35e-05 | 3.49e-01 | 2.10e-04 |
| CELLULAR RESPONSE TO STARVATION | 145 | 4.96e-13 | 3.48e-01 | 3.61e-11 |
| PYRUVATE METABOLISM | 27 | 1.77e-03 | 3.48e-01 | 1.14e-02 |
| ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | 11 | 4.63e-02 | 3.47e-01 | 1.37e-01 |
| STABILIZATION OF P53 | 54 | 1.07e-05 | 3.46e-01 | 1.73e-04 |
| MITOCHONDRIAL PROTEIN IMPORT | 63 | 2.19e-06 | 3.45e-01 | 5.02e-05 |
| TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | 13 | 3.17e-02 | 3.44e-01 | 1.03e-01 |
| RECEPTOR MEDIATED MITOPHAGY | 11 | 4.89e-02 | 3.43e-01 | 1.41e-01 |
| COLLAGEN CHAIN TRIMERIZATION | 39 | 2.27e-04 | -3.41e-01 | 2.07e-03 |
| DEGRADATION OF AXIN | 53 | 1.74e-05 | 3.41e-01 | 2.60e-04 |
| CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE | 11 | 5.01e-02 | 3.41e-01 | 1.43e-01 |
| RESPONSE OF MTB TO PHAGOCYTOSIS | 21 | 6.94e-03 | 3.40e-01 | 3.25e-02 |
| PENTOSE PHOSPHATE PATHWAY | 13 | 3.55e-02 | 3.37e-01 | 1.11e-01 |
| DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING | 59 | 7.79e-06 | 3.37e-01 | 1.34e-04 |
| INITIAL TRIGGERING OF COMPLEMENT | 10 | 6.55e-02 | 3.36e-01 | 1.77e-01 |
| THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | 28 | 2.08e-03 | 3.36e-01 | 1.29e-02 |
| DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX | 82 | 1.58e-07 | 3.35e-01 | 4.97e-06 |
| SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS | 12 | 4.51e-02 | 3.34e-01 | 1.34e-01 |
| SCF SKP2 MEDIATED DEGRADATION OF P27 P21 | 59 | 1.04e-05 | 3.32e-01 | 1.71e-04 |
| GLUTATHIONE SYNTHESIS AND RECYCLING | 11 | 5.76e-02 | 3.31e-01 | 1.59e-01 |
| BETA CATENIN PHOSPHORYLATION CASCADE | 16 | 2.28e-02 | 3.29e-01 | 8.35e-02 |
| RHO GTPASES ACTIVATE WASPS AND WAVES | 36 | 6.48e-04 | 3.29e-01 | 5.22e-03 |
| TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX | 15 | 2.80e-02 | 3.28e-01 | 9.54e-02 |
| KILLING MECHANISMS | 10 | 7.29e-02 | -3.28e-01 | 1.91e-01 |
| INTERACTION BETWEEN L1 AND ANKYRINS | 29 | 2.28e-03 | -3.27e-01 | 1.39e-02 |
| REGULATION OF TLR BY ENDOGENOUS LIGAND | 11 | 6.04e-02 | 3.27e-01 | 1.65e-01 |
| O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS | 36 | 7.18e-04 | -3.26e-01 | 5.51e-03 |
| REGULATION OF PTEN STABILITY AND ACTIVITY | 66 | 4.88e-06 | 3.25e-01 | 9.13e-05 |
| FCERI MEDIATED NF KB ACTIVATION | 76 | 9.91e-07 | 3.25e-01 | 2.57e-05 |
| PI 3K CASCADE FGFR2 | 16 | 2.49e-02 | 3.24e-01 | 8.75e-02 |
| CELLULAR RESPONSE TO HYPOXIA | 71 | 2.42e-06 | 3.24e-01 | 5.34e-05 |
| FORMATION OF FIBRIN CLOT CLOTTING CASCADE | 21 | 1.05e-02 | 3.23e-01 | 4.57e-02 |
| PKMTS METHYLATE HISTONE LYSINES | 48 | 1.17e-04 | -3.21e-01 | 1.16e-03 |
| TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT | 18 | 1.85e-02 | 3.21e-01 | 7.21e-02 |
| PHASE II CONJUGATION OF COMPOUNDS | 60 | 1.78e-05 | 3.20e-01 | 2.60e-04 |
| ANTIGEN PROCESSING CROSS PRESENTATION | 93 | 9.46e-08 | 3.20e-01 | 3.22e-06 |
| TRANSFERRIN ENDOCYTOSIS AND RECYCLING | 26 | 4.75e-03 | 3.20e-01 | 2.43e-02 |
| CELL EXTRACELLULAR MATRIX INTERACTIONS | 18 | 1.94e-02 | 3.18e-01 | 7.41e-02 |
| LDL CLEARANCE | 16 | 2.78e-02 | 3.18e-01 | 9.50e-02 |
| PROTEIN UBIQUITINATION | 69 | 5.08e-06 | 3.18e-01 | 9.26e-05 |
| REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | 15 | 3.38e-02 | 3.17e-01 | 1.08e-01 |
| IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | 21 | 1.23e-02 | 3.16e-01 | 5.22e-02 |
| TIE2 SIGNALING | 17 | 2.46e-02 | 3.15e-01 | 8.74e-02 |
| G PROTEIN ACTIVATION | 22 | 1.07e-02 | 3.14e-01 | 4.65e-02 |
| SIGNALING BY FGFR4 IN DISEASE | 10 | 8.53e-02 | 3.14e-01 | 2.11e-01 |
| PROTEIN LOCALIZATION | 156 | 1.39e-11 | 3.14e-01 | 9.02e-10 |
| ROS AND RNS PRODUCTION IN PHAGOCYTES | 28 | 4.08e-03 | 3.14e-01 | 2.13e-02 |
| NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 11 | 7.19e-02 | -3.13e-01 | 1.89e-01 |
| BUDDING AND MATURATION OF HIV VIRION | 27 | 4.84e-03 | 3.13e-01 | 2.45e-02 |
| SPHINGOLIPID DE NOVO BIOSYNTHESIS | 41 | 5.24e-04 | 3.13e-01 | 4.31e-03 |
| ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | 30 | 3.17e-03 | 3.11e-01 | 1.78e-02 |
| INFLAMMASOMES | 19 | 1.89e-02 | 3.11e-01 | 7.30e-02 |
| NUCLEOBASE BIOSYNTHESIS | 15 | 3.71e-02 | 3.11e-01 | 1.15e-01 |
| IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX | 10 | 8.87e-02 | 3.11e-01 | 2.17e-01 |
| SYNAPTIC ADHESION LIKE MOLECULES | 21 | 1.38e-02 | -3.11e-01 | 5.72e-02 |
| NEGATIVE REGULATION OF FGFR3 SIGNALING | 23 | 1.00e-02 | 3.10e-01 | 4.43e-02 |
| ANCHORING FIBRIL FORMATION | 13 | 5.32e-02 | -3.10e-01 | 1.50e-01 |
| THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT | 66 | 1.47e-05 | 3.08e-01 | 2.23e-04 |
| RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY | 14 | 4.62e-02 | 3.08e-01 | 1.37e-01 |
| REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO | 10 | 9.22e-02 | -3.08e-01 | 2.24e-01 |
| INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE | 22 | 1.26e-02 | 3.07e-01 | 5.31e-02 |
| FATTY ACID METABOLISM | 146 | 1.71e-10 | 3.06e-01 | 9.53e-09 |
| PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS | 19 | 2.08e-02 | 3.06e-01 | 7.74e-02 |
| IRAK4 DEFICIENCY TLR2 4 | 12 | 6.64e-02 | 3.06e-01 | 1.79e-01 |
| SIGNALING BY THE B CELL RECEPTOR BCR | 103 | 9.14e-08 | 3.05e-01 | 3.22e-06 |
| INFLUENZA INFECTION | 145 | 2.45e-10 | 3.05e-01 | 1.24e-08 |
| DEGRADATION OF DVL | 55 | 9.43e-05 | 3.04e-01 | 9.83e-04 |
| MITOCHONDRIAL FATTY ACID BETA OXIDATION | 33 | 2.59e-03 | 3.03e-01 | 1.53e-02 |
| SIGNALING BY ROBO RECEPTORS | 205 | 8.04e-14 | 3.03e-01 | 6.60e-12 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 | 23 | 1.20e-02 | 3.03e-01 | 5.13e-02 |
| SIGNALING BY FGFR4 | 31 | 3.56e-03 | 3.03e-01 | 1.92e-02 |
| NEGATIVE REGULATION OF FGFR4 SIGNALING | 21 | 1.65e-02 | 3.02e-01 | 6.61e-02 |
| RHOBTB2 GTPASE CYCLE | 23 | 1.24e-02 | 3.01e-01 | 5.24e-02 |
| ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K | 11 | 8.47e-02 | 3.00e-01 | 2.11e-01 |
| ORC1 REMOVAL FROM CHROMATIN | 67 | 2.31e-05 | 2.99e-01 | 3.21e-04 |
| GPVI MEDIATED ACTIVATION CASCADE | 31 | 3.97e-03 | 2.99e-01 | 2.09e-02 |
| FRS MEDIATED FGFR1 SIGNALING | 17 | 3.30e-02 | 2.99e-01 | 1.07e-01 |
| ASSEMBLY OF THE PRE REPLICATIVE COMPLEX | 64 | 3.79e-05 | 2.98e-01 | 4.86e-04 |
| ABC TRANSPORTER DISORDERS | 69 | 1.94e-05 | 2.97e-01 | 2.76e-04 |
| IRF3 MEDIATED INDUCTION OF TYPE I IFN | 11 | 8.87e-02 | -2.96e-01 | 2.17e-01 |
| GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION | 32 | 3.82e-03 | 2.95e-01 | 2.05e-02 |
| SULFUR AMINO ACID METABOLISM | 22 | 1.66e-02 | 2.95e-01 | 6.61e-02 |
| GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | 14 | 5.69e-02 | 2.94e-01 | 1.58e-01 |
| SEROTONIN RECEPTORS | 10 | 1.09e-01 | 2.93e-01 | 2.49e-01 |
| AQUAPORIN MEDIATED TRANSPORT | 40 | 1.37e-03 | 2.93e-01 | 9.05e-03 |
| CLEC7A DECTIN 1 SIGNALING | 94 | 9.55e-07 | 2.93e-01 | 2.53e-05 |
| APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | 69 | 2.88e-05 | 2.91e-01 | 3.91e-04 |
| SARS COV 2 INFECTION | 65 | 4.94e-05 | 2.91e-01 | 6.07e-04 |
| GLUCAGON SIGNALING IN METABOLIC REGULATION | 29 | 6.67e-03 | 2.91e-01 | 3.18e-02 |
| SCAVENGING BY CLASS A RECEPTORS | 13 | 6.96e-02 | 2.91e-01 | 1.85e-01 |
| CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY | 84 | 4.16e-06 | 2.91e-01 | 8.52e-05 |
| CHAPERONE MEDIATED AUTOPHAGY | 20 | 2.48e-02 | 2.90e-01 | 8.75e-02 |
| REGULATION OF MECP2 EXPRESSION AND ACTIVITY | 30 | 5.99e-03 | -2.90e-01 | 2.90e-02 |
| LYSOSOME VESICLE BIOGENESIS | 33 | 3.97e-03 | 2.90e-01 | 2.09e-02 |
| C TYPE LECTIN RECEPTORS CLRS | 111 | 1.38e-07 | 2.90e-01 | 4.49e-06 |
| ANTIMICROBIAL PEPTIDES | 14 | 6.09e-02 | 2.89e-01 | 1.66e-01 |
| BBSOME MEDIATED CARGO TARGETING TO CILIUM | 23 | 1.64e-02 | 2.89e-01 | 6.61e-02 |
| DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | 26 | 1.08e-02 | 2.89e-01 | 4.65e-02 |
| REGULATION OF RUNX2 EXPRESSION AND ACTIVITY | 69 | 3.40e-05 | 2.89e-01 | 4.51e-04 |
| VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS | 37 | 2.47e-03 | 2.88e-01 | 1.47e-02 |
| BIOLOGICAL OXIDATIONS | 123 | 3.90e-08 | 2.87e-01 | 1.52e-06 |
| PLATELET ADHESION TO EXPOSED COLLAGEN | 12 | 8.54e-02 | 2.87e-01 | 2.11e-01 |
| SEROTONIN NEUROTRANSMITTER RELEASE CYCLE | 18 | 3.54e-02 | -2.86e-01 | 1.11e-01 |
| PROCESSING AND ACTIVATION OF SUMO | 10 | 1.17e-01 | 2.86e-01 | 2.65e-01 |
| MET RECEPTOR RECYCLING | 10 | 1.18e-01 | 2.86e-01 | 2.65e-01 |
| TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX | 11 | 1.01e-01 | 2.85e-01 | 2.39e-01 |
| G1 S DNA DAMAGE CHECKPOINTS | 65 | 7.57e-05 | 2.84e-01 | 8.25e-04 |
| TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | 32 | 5.51e-03 | 2.84e-01 | 2.70e-02 |
| ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING | 10 | 1.23e-01 | -2.82e-01 | 2.74e-01 |
| PYROPTOSIS | 20 | 2.90e-02 | 2.82e-01 | 9.79e-02 |
| REGULATION OF RAS BY GAPS | 66 | 7.74e-05 | 2.81e-01 | 8.32e-04 |
| INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION | 13 | 7.92e-02 | 2.81e-01 | 2.01e-01 |
| RAF ACTIVATION | 34 | 4.84e-03 | 2.79e-01 | 2.45e-02 |
| E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS | 50 | 6.53e-04 | 2.79e-01 | 5.22e-03 |
| SIGNALING BY FGFR3 | 34 | 5.06e-03 | 2.78e-01 | 2.55e-02 |
| COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING | 26 | 1.43e-02 | 2.77e-01 | 5.91e-02 |
| INCRETIN SYNTHESIS SECRETION AND INACTIVATION | 13 | 8.37e-02 | 2.77e-01 | 2.10e-01 |
| HYALURONAN UPTAKE AND DEGRADATION | 11 | 1.12e-01 | 2.77e-01 | 2.55e-01 |
| ABC FAMILY PROTEINS MEDIATED TRANSPORT | 93 | 4.93e-06 | 2.74e-01 | 9.13e-05 |
| RHO GTPASES ACTIVATE KTN1 | 11 | 1.16e-01 | 2.74e-01 | 2.63e-01 |
| DERMATAN SULFATE BIOSYNTHESIS | 11 | 1.16e-01 | 2.73e-01 | 2.64e-01 |
| FC EPSILON RECEPTOR FCERI SIGNALING | 123 | 1.70e-07 | 2.73e-01 | 5.23e-06 |
| CELLULAR RESPONSE TO CHEMICAL STRESS | 149 | 9.40e-09 | 2.73e-01 | 4.06e-07 |
| INTERLEUKIN 12 SIGNALING | 37 | 4.38e-03 | 2.71e-01 | 2.27e-02 |
| RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | 107 | 1.36e-06 | 2.70e-01 | 3.23e-05 |
| SPHINGOLIPID METABOLISM | 79 | 3.53e-05 | 2.69e-01 | 4.58e-04 |
| SIGNALING BY RETINOIC ACID | 32 | 8.60e-03 | 2.68e-01 | 3.94e-02 |
| SHC MEDIATED CASCADE FGFR1 | 15 | 7.19e-02 | 2.68e-01 | 1.89e-01 |
| NOTCH HLH TRANSCRIPTION PATHWAY | 28 | 1.43e-02 | -2.68e-01 | 5.91e-02 |
| TNFR2 NON CANONICAL NF KB PATHWAY | 79 | 4.11e-05 | 2.67e-01 | 5.16e-04 |
| CS DS DEGRADATION | 14 | 8.45e-02 | 2.66e-01 | 2.11e-01 |
| FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | 19 | 4.51e-02 | 2.66e-01 | 1.34e-01 |
| SARS COV 1 INFECTION | 48 | 1.48e-03 | 2.65e-01 | 9.74e-03 |
| NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX | 32 | 9.42e-03 | -2.65e-01 | 4.21e-02 |
| INTERLEUKIN 1 SIGNALING | 95 | 8.15e-06 | 2.65e-01 | 1.38e-04 |
| MITOCHONDRIAL CALCIUM ION TRANSPORT | 23 | 2.80e-02 | 2.65e-01 | 9.54e-02 |
| PI 3K CASCADE FGFR1 | 15 | 7.71e-02 | 2.64e-01 | 1.98e-01 |
| INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL | 15 | 7.76e-02 | 2.63e-01 | 1.99e-01 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 | 25 | 2.32e-02 | 2.62e-01 | 8.45e-02 |
| ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | 23 | 2.94e-02 | 2.62e-01 | 9.89e-02 |
| DNA REPLICATION PRE INITIATION | 79 | 5.65e-05 | 2.62e-01 | 6.62e-04 |
| CROSSLINKING OF COLLAGEN FIBRILS | 13 | 1.03e-01 | -2.62e-01 | 2.40e-01 |
| ASYMMETRIC LOCALIZATION OF PCP PROTEINS | 62 | 3.78e-04 | 2.61e-01 | 3.30e-03 |
| RRNA PROCESSING | 194 | 3.84e-10 | 2.61e-01 | 1.87e-08 |
| DISEASES OF CARBOHYDRATE METABOLISM | 29 | 1.52e-02 | 2.61e-01 | 6.19e-02 |
| APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS | 80 | 5.71e-05 | 2.60e-01 | 6.62e-04 |
| TRANS GOLGI NETWORK VESICLE BUDDING | 70 | 1.67e-04 | 2.60e-01 | 1.58e-03 |
| NEUTROPHIL DEGRANULATION | 384 | 2.39e-18 | 2.60e-01 | 3.10e-16 |
| INTERLEUKIN 12 FAMILY SIGNALING | 44 | 2.86e-03 | 2.60e-01 | 1.65e-02 |
| FCERI MEDIATED CA 2 MOBILIZATION | 26 | 2.21e-02 | 2.59e-01 | 8.14e-02 |
| SYNTHESIS OF BILE ACIDS AND BILE SALTS | 21 | 3.98e-02 | 2.59e-01 | 1.22e-01 |
| WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 | 13 | 1.06e-01 | 2.59e-01 | 2.47e-01 |
| P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 12 | 1.21e-01 | 2.58e-01 | 2.71e-01 |
| PEROXISOMAL LIPID METABOLISM | 26 | 2.28e-02 | 2.58e-01 | 8.35e-02 |
| PURINE CATABOLISM | 16 | 7.48e-02 | 2.57e-01 | 1.95e-01 |
| MATURATION OF SARS COV 2 SPIKE PROTEIN | 29 | 1.65e-02 | 2.57e-01 | 6.61e-02 |
| TCR SIGNALING | 101 | 8.26e-06 | 2.57e-01 | 1.38e-04 |
| SIGNALING BY BMP | 24 | 2.95e-02 | 2.57e-01 | 9.89e-02 |
| THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS | 27 | 2.17e-02 | 2.55e-01 | 8.00e-02 |
| SIGNALING BY NOTCH4 | 83 | 6.43e-05 | 2.54e-01 | 7.22e-04 |
| ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING | 28 | 2.06e-02 | 2.53e-01 | 7.67e-02 |
| METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES | 21 | 4.49e-02 | 2.53e-01 | 1.34e-01 |
| G PROTEIN BETA GAMMA SIGNALLING | 30 | 1.66e-02 | 2.53e-01 | 6.61e-02 |
| VEGFR2 MEDIATED VASCULAR PERMEABILITY | 26 | 2.60e-02 | 2.52e-01 | 9.03e-02 |
| SIGNALING BY INSULIN RECEPTOR | 61 | 6.68e-04 | 2.52e-01 | 5.27e-03 |
| KINESINS | 47 | 2.82e-03 | -2.52e-01 | 1.63e-02 |
| INACTIVATION OF CSF3 G CSF SIGNALING | 24 | 3.52e-02 | 2.48e-01 | 1.11e-01 |
| CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | 89 | 5.19e-05 | 2.48e-01 | 6.31e-04 |
| RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS | 81 | 1.17e-04 | 2.48e-01 | 1.16e-03 |
| ARACHIDONIC ACID METABOLISM | 40 | 6.76e-03 | 2.48e-01 | 3.21e-02 |
| TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | 17 | 7.73e-02 | -2.47e-01 | 1.98e-01 |
| DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | 23 | 4.04e-02 | -2.47e-01 | 1.23e-01 |
| GLUTAMATE AND GLUTAMINE METABOLISM | 13 | 1.24e-01 | 2.47e-01 | 2.76e-01 |
| NCAM1 INTERACTIONS | 39 | 7.84e-03 | -2.46e-01 | 3.61e-02 |
| COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES | 62 | 8.37e-04 | -2.45e-01 | 6.11e-03 |
| PYRIMIDINE SALVAGE | 10 | 1.80e-01 | -2.45e-01 | 3.55e-01 |
| GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION | 11 | 1.60e-01 | 2.45e-01 | 3.27e-01 |
| ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION | 26 | 3.10e-02 | 2.44e-01 | 1.02e-01 |
| MET ACTIVATES RAP1 AND RAC1 | 11 | 1.61e-01 | 2.44e-01 | 3.28e-01 |
| PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR | 20 | 5.97e-02 | 2.43e-01 | 1.64e-01 |
| METABOLISM OF COFACTORS | 18 | 7.40e-02 | 2.43e-01 | 1.93e-01 |
| INWARDLY RECTIFYING K CHANNELS | 31 | 1.97e-02 | 2.42e-01 | 7.51e-02 |
| ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS | 10 | 1.85e-01 | -2.42e-01 | 3.63e-01 |
| SIGNALING BY CSF3 G CSF | 29 | 2.44e-02 | 2.42e-01 | 8.74e-02 |
| CYTOPROTECTION BY HMOX1 | 119 | 5.64e-06 | 2.41e-01 | 9.98e-05 |
| SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE | 86 | 1.22e-04 | 2.40e-01 | 1.18e-03 |
| GLUCAGON TYPE LIGAND RECEPTORS | 23 | 4.68e-02 | 2.40e-01 | 1.37e-01 |
| NEGATIVE REGULATION OF FGFR2 SIGNALING | 27 | 3.19e-02 | 2.39e-01 | 1.03e-01 |
| PLATELET ACTIVATION SIGNALING AND AGGREGATION | 225 | 7.46e-10 | 2.38e-01 | 3.35e-08 |
| MAPK6 MAPK4 SIGNALING | 83 | 1.81e-04 | 2.38e-01 | 1.69e-03 |
| HOST INTERACTIONS OF HIV FACTORS | 125 | 4.78e-06 | 2.37e-01 | 9.13e-05 |
| SIGNALING BY ERBB2 ECD MUTANTS | 16 | 1.01e-01 | 2.37e-01 | 2.38e-01 |
| PHASE I FUNCTIONALIZATION OF COMPOUNDS | 60 | 1.72e-03 | 2.34e-01 | 1.11e-02 |
| PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION | 22 | 5.79e-02 | 2.34e-01 | 1.60e-01 |
| SUMOYLATION OF TRANSCRIPTION FACTORS | 17 | 9.57e-02 | 2.33e-01 | 2.30e-01 |
| PROLONGED ERK ACTIVATION EVENTS | 14 | 1.31e-01 | 2.33e-01 | 2.85e-01 |
| EXTRA NUCLEAR ESTROGEN SIGNALING | 67 | 9.68e-04 | 2.33e-01 | 7.01e-03 |
| INITIATION OF NUCLEAR ENVELOPE NE REFORMATION | 16 | 1.08e-01 | 2.32e-01 | 2.48e-01 |
| N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | 23 | 5.38e-02 | 2.32e-01 | 1.51e-01 |
| PEXOPHAGY | 11 | 1.83e-01 | 2.32e-01 | 3.61e-01 |
| GOLGI ASSOCIATED VESICLE BIOGENESIS | 55 | 3.18e-03 | 2.30e-01 | 1.78e-02 |
| S PHASE | 153 | 9.32e-07 | 2.30e-01 | 2.53e-05 |
| TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | 13 | 1.53e-01 | -2.29e-01 | 3.18e-01 |
| METALLOPROTEASE DUBS | 25 | 4.76e-02 | 2.29e-01 | 1.39e-01 |
| DAP12 INTERACTIONS | 29 | 3.32e-02 | 2.29e-01 | 1.07e-01 |
| INTERLEUKIN 1 FAMILY SIGNALING | 123 | 1.26e-05 | 2.28e-01 | 2.02e-04 |
| METABOLISM OF PORPHYRINS | 19 | 8.56e-02 | 2.28e-01 | 2.11e-01 |
| MISCELLANEOUS TRANSPORT AND BINDING EVENTS | 20 | 7.94e-02 | 2.27e-01 | 2.01e-01 |
| EARLY PHASE OF HIV LIFE CYCLE | 14 | 1.43e-01 | 2.26e-01 | 3.03e-01 |
| EPHRIN SIGNALING | 19 | 8.78e-02 | 2.26e-01 | 2.16e-01 |
| NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | 11 | 1.97e-01 | 2.25e-01 | 3.75e-01 |
| FORMATION OF APOPTOSOME | 10 | 2.19e-01 | 2.25e-01 | 3.95e-01 |
| RAB GERANYLGERANYLATION | 58 | 3.16e-03 | 2.24e-01 | 1.78e-02 |
| PEROXISOMAL PROTEIN IMPORT | 57 | 3.44e-03 | 2.24e-01 | 1.89e-02 |
| SIGNALING BY FGFR1 | 43 | 1.11e-02 | 2.24e-01 | 4.76e-02 |
| DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS | 51 | 5.79e-03 | -2.23e-01 | 2.83e-02 |
| PHASE 0 RAPID DEPOLARISATION | 31 | 3.14e-02 | -2.23e-01 | 1.03e-01 |
| LGI ADAM INTERACTIONS | 14 | 1.49e-01 | -2.23e-01 | 3.11e-01 |
| GABA RECEPTOR ACTIVATION | 52 | 5.49e-03 | 2.23e-01 | 2.70e-02 |
| RHO GTPASES ACTIVATE CIT | 18 | 1.03e-01 | 2.22e-01 | 2.40e-01 |
| GABA B RECEPTOR ACTIVATION | 39 | 1.64e-02 | 2.22e-01 | 6.61e-02 |
| N GLYCAN ANTENNAE ELONGATION | 15 | 1.37e-01 | 2.22e-01 | 2.94e-01 |
| GLYCOSPHINGOLIPID METABOLISM | 38 | 1.86e-02 | 2.21e-01 | 7.23e-02 |
| SHC1 EVENTS IN EGFR SIGNALING | 11 | 2.06e-01 | 2.20e-01 | 3.81e-01 |
| SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL | 10 | 2.28e-01 | 2.20e-01 | 4.06e-01 |
| SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 | 12 | 1.88e-01 | 2.20e-01 | 3.65e-01 |
| INNATE IMMUNE SYSTEM | 772 | 5.71e-25 | 2.19e-01 | 1.67e-22 |
| THE NLRP3 INFLAMMASOME | 15 | 1.43e-01 | 2.19e-01 | 3.03e-01 |
| E2F MEDIATED REGULATION OF DNA REPLICATION | 19 | 9.95e-02 | 2.18e-01 | 2.36e-01 |
| COSTIMULATION BY THE CD28 FAMILY | 48 | 9.04e-03 | 2.18e-01 | 4.10e-02 |
| TRANSCRIPTIONAL REGULATION BY RUNX3 | 92 | 3.09e-04 | 2.18e-01 | 2.75e-03 |
| PARASITE INFECTION | 55 | 5.29e-03 | 2.17e-01 | 2.64e-02 |
| SYNDECAN INTERACTIONS | 26 | 5.55e-02 | 2.17e-01 | 1.56e-01 |
| GAP JUNCTION TRAFFICKING AND REGULATION | 33 | 3.12e-02 | 2.17e-01 | 1.02e-01 |
| DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | 13 | 1.76e-01 | 2.17e-01 | 3.51e-01 |
| SIGNALING BY FGFR2 IN DISEASE | 36 | 2.45e-02 | 2.17e-01 | 8.74e-02 |
| COHESIN LOADING ONTO CHROMATIN | 10 | 2.36e-01 | 2.16e-01 | 4.16e-01 |
| CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX | 10 | 2.36e-01 | 2.16e-01 | 4.16e-01 |
| FCERI MEDIATED MAPK ACTIVATION | 28 | 5.01e-02 | 2.14e-01 | 1.43e-01 |
| INTRAFLAGELLAR TRANSPORT | 49 | 9.72e-03 | -2.14e-01 | 4.33e-02 |
| SIGNALING BY FGFR2 IIIA TM | 19 | 1.07e-01 | 2.13e-01 | 2.48e-01 |
| GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | 18 | 1.17e-01 | 2.13e-01 | 2.65e-01 |
| BILE ACID AND BILE SALT METABOLISM | 24 | 7.14e-02 | 2.13e-01 | 1.89e-01 |
| SMOOTH MUSCLE CONTRACTION | 33 | 3.49e-02 | 2.12e-01 | 1.11e-01 |
| CD209 DC SIGN SIGNALING | 18 | 1.19e-01 | 2.12e-01 | 2.68e-01 |
| BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS | 12 | 2.03e-01 | 2.12e-01 | 3.80e-01 |
| LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS | 20 | 1.01e-01 | 2.12e-01 | 2.39e-01 |
| ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY | 11 | 2.25e-01 | 2.11e-01 | 4.04e-01 |
| GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION | 38 | 2.45e-02 | 2.11e-01 | 8.74e-02 |
| ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | 16 | 1.44e-01 | 2.11e-01 | 3.05e-01 |
| MITOTIC G1 PHASE AND G1 S TRANSITION | 140 | 1.85e-05 | 2.10e-01 | 2.67e-04 |
| IRS MEDIATED SIGNALLING | 37 | 2.76e-02 | 2.09e-01 | 9.48e-02 |
| CYTOSOLIC TRNA AMINOACYLATION | 24 | 7.67e-02 | 2.09e-01 | 1.98e-01 |
| PERK REGULATES GENE EXPRESSION | 28 | 5.66e-02 | 2.08e-01 | 1.58e-01 |
| GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 12 | 2.13e-01 | 2.08e-01 | 3.89e-01 |
| MRNA SPLICING MINOR PATHWAY | 52 | 1.02e-02 | 2.06e-01 | 4.49e-02 |
| FOXO MEDIATED TRANSCRIPTION | 59 | 6.48e-03 | 2.05e-01 | 3.10e-02 |
| ERKS ARE INACTIVATED | 13 | 2.02e-01 | 2.05e-01 | 3.79e-01 |
| SIGNALING BY EGFR IN CANCER | 22 | 9.83e-02 | 2.04e-01 | 2.35e-01 |
| REGULATED PROTEOLYSIS OF P75NTR | 12 | 2.22e-01 | 2.04e-01 | 4.00e-01 |
| REGULATION OF BACH1 ACTIVITY | 11 | 2.44e-01 | 2.03e-01 | 4.21e-01 |
| RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX | 29 | 5.88e-02 | 2.03e-01 | 1.62e-01 |
| TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS | 44 | 2.01e-02 | 2.03e-01 | 7.54e-02 |
| MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | 15 | 1.76e-01 | -2.02e-01 | 3.51e-01 |
| OPIOID SIGNALLING | 86 | 1.26e-03 | 2.01e-01 | 8.40e-03 |
| PLASMA LIPOPROTEIN CLEARANCE | 26 | 7.59e-02 | 2.01e-01 | 1.97e-01 |
| FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS | 82 | 1.65e-03 | 2.01e-01 | 1.07e-02 |
| FCGR3A MEDIATED IL10 SYNTHESIS | 32 | 4.91e-02 | 2.01e-01 | 1.41e-01 |
| SIGNALING BY WNT IN CANCER | 31 | 5.32e-02 | 2.01e-01 | 1.50e-01 |
| NEGATIVE REGULATION OF FGFR1 SIGNALING | 26 | 7.68e-02 | 2.01e-01 | 1.98e-01 |
| REGULATED NECROSIS | 45 | 2.00e-02 | 2.00e-01 | 7.54e-02 |
| DNA REPLICATION | 121 | 1.48e-04 | 2.00e-01 | 1.41e-03 |
| PCP CE PATHWAY | 90 | 1.08e-03 | 2.00e-01 | 7.61e-03 |
| DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | 23 | 9.81e-02 | 1.99e-01 | 2.35e-01 |
| ACTIVATION OF SMO | 16 | 1.68e-01 | -1.99e-01 | 3.37e-01 |
| CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS | 19 | 1.33e-01 | 1.99e-01 | 2.88e-01 |
| RHOH GTPASE CYCLE | 37 | 3.63e-02 | 1.99e-01 | 1.13e-01 |
| UPTAKE AND FUNCTION OF ANTHRAX TOXINS | 11 | 2.54e-01 | 1.98e-01 | 4.32e-01 |
| KERATAN SULFATE BIOSYNTHESIS | 24 | 9.25e-02 | 1.98e-01 | 2.24e-01 |
| DAP12 SIGNALING | 24 | 9.29e-02 | 1.98e-01 | 2.24e-01 |
| REGULATION OF SIGNALING BY CBL | 22 | 1.08e-01 | 1.98e-01 | 2.48e-01 |
| NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | 17 | 1.58e-01 | 1.98e-01 | 3.24e-01 |
| PURINE SALVAGE | 12 | 2.36e-01 | 1.97e-01 | 4.16e-01 |
| FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF | 13 | 2.18e-01 | -1.97e-01 | 3.94e-01 |
| SIGNALING BY ERYTHROPOIETIN | 24 | 9.46e-02 | 1.97e-01 | 2.28e-01 |
| RHO GTPASES ACTIVATE PKNS | 47 | 1.98e-02 | 1.96e-01 | 7.51e-02 |
| TRANSCRIPTIONAL REGULATION BY RUNX2 | 110 | 3.94e-04 | 1.96e-01 | 3.34e-03 |
| HEDGEHOG ON STATE | 82 | 2.24e-03 | 1.95e-01 | 1.37e-02 |
| SPRY REGULATION OF FGF SIGNALING | 16 | 1.77e-01 | 1.95e-01 | 3.52e-01 |
| INFECTIOUS DISEASE | 727 | 9.98e-19 | 1.93e-01 | 1.66e-16 |
| EPHB MEDIATED FORWARD SIGNALING | 42 | 3.06e-02 | 1.93e-01 | 1.02e-01 |
| SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R | 42 | 3.06e-02 | 1.93e-01 | 1.02e-01 |
| PROLACTIN RECEPTOR SIGNALING | 11 | 2.69e-01 | 1.93e-01 | 4.46e-01 |
| GAP JUNCTION ASSEMBLY | 21 | 1.27e-01 | 1.92e-01 | 2.80e-01 |
| GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER | 24 | 1.05e-01 | 1.91e-01 | 2.45e-01 |
| TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 43 | 3.03e-02 | -1.91e-01 | 1.01e-01 |
| SIGNALING BY NTRK3 TRKC | 17 | 1.76e-01 | -1.90e-01 | 3.51e-01 |
| HEME SIGNALING | 44 | 2.97e-02 | -1.89e-01 | 9.94e-02 |
| UCH PROTEINASES | 88 | 2.15e-03 | 1.89e-01 | 1.32e-02 |
| TRANSLESION SYNTHESIS BY POLH | 19 | 1.53e-01 | 1.89e-01 | 3.18e-01 |
| CYTOSOLIC SULFONATION OF SMALL MOLECULES | 15 | 2.05e-01 | 1.89e-01 | 3.81e-01 |
| SARS COV INFECTIONS | 139 | 1.27e-04 | 1.88e-01 | 1.23e-03 |
| REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | 88 | 2.37e-03 | 1.88e-01 | 1.42e-02 |
| PHASE 2 PLATEAU PHASE | 13 | 2.42e-01 | -1.88e-01 | 4.18e-01 |
| NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS | 11 | 2.82e-01 | -1.87e-01 | 4.60e-01 |
| TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES | 10 | 3.06e-01 | -1.87e-01 | 4.83e-01 |
| SIGNALING BY HIPPO | 20 | 1.48e-01 | 1.87e-01 | 3.10e-01 |
| REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | 84 | 3.11e-03 | 1.87e-01 | 1.76e-02 |
| PROGRAMMED CELL DEATH | 185 | 1.28e-05 | 1.86e-01 | 2.02e-04 |
| REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM | 11 | 2.85e-01 | 1.86e-01 | 4.64e-01 |
| CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND | 13 | 2.47e-01 | 1.86e-01 | 4.23e-01 |
| WNT LIGAND BIOGENESIS AND TRAFFICKING | 21 | 1.43e-01 | 1.85e-01 | 3.03e-01 |
| VOLTAGE GATED POTASSIUM CHANNELS | 40 | 4.35e-02 | -1.85e-01 | 1.31e-01 |
| ACTIVATION OF RAC1 | 13 | 2.50e-01 | 1.84e-01 | 4.28e-01 |
| INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING | 77 | 5.35e-03 | 1.84e-01 | 2.65e-02 |
| STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES | 14 | 2.35e-01 | -1.84e-01 | 4.15e-01 |
| DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX | 41 | 4.21e-02 | 1.83e-01 | 1.27e-01 |
| APOPTOSIS | 163 | 5.59e-05 | 1.83e-01 | 6.62e-04 |
| LAGGING STRAND SYNTHESIS | 20 | 1.56e-01 | 1.83e-01 | 3.23e-01 |
| TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN | 11 | 2.96e-01 | 1.82e-01 | 4.73e-01 |
| UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION | 21 | 1.49e-01 | -1.82e-01 | 3.12e-01 |
| RESOLUTION OF D LOOP STRUCTURES | 30 | 8.48e-02 | -1.82e-01 | 2.11e-01 |
| SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX | 13 | 2.57e-01 | 1.82e-01 | 4.34e-01 |
| RHOBTB GTPASE CYCLE | 35 | 6.31e-02 | 1.82e-01 | 1.72e-01 |
| KERATAN SULFATE KERATIN METABOLISM | 30 | 8.53e-02 | 1.82e-01 | 2.11e-01 |
| GENERATION OF SECOND MESSENGER MOLECULES | 20 | 1.60e-01 | 1.82e-01 | 3.27e-01 |
| NF KB IS ACTIVATED AND SIGNALS SURVIVAL | 13 | 2.59e-01 | 1.81e-01 | 4.36e-01 |
| RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES | 20 | 1.61e-01 | -1.81e-01 | 3.28e-01 |
| INTEGRIN SIGNALING | 24 | 1.25e-01 | 1.81e-01 | 2.78e-01 |
| RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION | 50 | 2.74e-02 | -1.80e-01 | 9.44e-02 |
| PKA MEDIATED PHOSPHORYLATION OF CREB | 19 | 1.74e-01 | 1.80e-01 | 3.48e-01 |
| CGMP EFFECTS | 15 | 2.27e-01 | -1.80e-01 | 4.06e-01 |
| PRE NOTCH PROCESSING IN GOLGI | 17 | 1.99e-01 | 1.80e-01 | 3.78e-01 |
| RAP1 SIGNALLING | 15 | 2.28e-01 | 1.80e-01 | 4.06e-01 |
| INTERLEUKIN 7 SIGNALING | 20 | 1.65e-01 | -1.79e-01 | 3.33e-01 |
| TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX | 17 | 2.01e-01 | 1.79e-01 | 3.79e-01 |
| FGFR2 MUTANT RECEPTOR ACTIVATION | 26 | 1.15e-01 | 1.79e-01 | 2.61e-01 |
| HIV INFECTION | 221 | 4.92e-06 | 1.79e-01 | 9.13e-05 |
| SEPARATION OF SISTER CHROMATIDS | 164 | 8.60e-05 | 1.78e-01 | 9.12e-04 |
| MUCOPOLYSACCHARIDOSES | 11 | 3.07e-01 | 1.78e-01 | 4.83e-01 |
| KERATAN SULFATE DEGRADATION | 11 | 3.09e-01 | 1.77e-01 | 4.84e-01 |
| TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS | 62 | 1.59e-02 | 1.77e-01 | 6.48e-02 |
| REGULATION OF TP53 ACTIVITY THROUGH METHYLATION | 18 | 1.94e-01 | -1.77e-01 | 3.70e-01 |
| INSULIN RECEPTOR SIGNALLING CASCADE | 42 | 4.74e-02 | 1.77e-01 | 1.39e-01 |
| CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS | 93 | 3.30e-03 | 1.76e-01 | 1.82e-02 |
| MITOTIC METAPHASE AND ANAPHASE | 204 | 1.44e-05 | 1.76e-01 | 2.22e-04 |
| INTERLEUKIN 10 SIGNALING | 17 | 2.09e-01 | 1.76e-01 | 3.84e-01 |
| SYNTHESIS OF PC | 25 | 1.28e-01 | 1.76e-01 | 2.81e-01 |
| GP1B IX V ACTIVATION SIGNALLING | 11 | 3.13e-01 | -1.76e-01 | 4.88e-01 |
| HEME BIOSYNTHESIS | 13 | 2.73e-01 | 1.76e-01 | 4.51e-01 |
| ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES | 10 | 3.36e-01 | -1.76e-01 | 5.13e-01 |
| G ALPHA Z SIGNALLING EVENTS | 45 | 4.16e-02 | 1.76e-01 | 1.26e-01 |
| SIGNALING BY INTERLEUKINS | 346 | 2.17e-08 | 1.76e-01 | 9.06e-07 |
| RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY | 24 | 1.38e-01 | 1.75e-01 | 2.96e-01 |
| UB SPECIFIC PROCESSING PROTEASES | 166 | 1.14e-04 | 1.74e-01 | 1.14e-03 |
| REGULATION OF FZD BY UBIQUITINATION | 19 | 1.91e-01 | 1.73e-01 | 3.67e-01 |
| TELOMERE EXTENSION BY TELOMERASE | 23 | 1.51e-01 | -1.73e-01 | 3.16e-01 |
| RHO GTPASES ACTIVATE ROCKS | 19 | 1.92e-01 | 1.73e-01 | 3.68e-01 |
| TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 | 12 | 3.01e-01 | 1.72e-01 | 4.79e-01 |
| ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE | 96 | 3.55e-03 | -1.72e-01 | 1.92e-02 |
| COLLAGEN FORMATION | 77 | 9.30e-03 | -1.72e-01 | 4.17e-02 |
| ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS | 26 | 1.30e-01 | 1.71e-01 | 2.85e-01 |
| PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 | 11 | 3.25e-01 | 1.71e-01 | 5.02e-01 |
| RHOQ GTPASE CYCLE | 58 | 2.49e-02 | 1.70e-01 | 8.75e-02 |
| G ALPHA I SIGNALLING EVENTS | 193 | 4.67e-05 | 1.70e-01 | 5.80e-04 |
| SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | 14 | 2.70e-01 | -1.70e-01 | 4.48e-01 |
| DISORDERS OF TRANSMEMBRANE TRANSPORTERS | 138 | 5.94e-04 | 1.69e-01 | 4.81e-03 |
| EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION | 27 | 1.29e-01 | 1.69e-01 | 2.82e-01 |
| HSF1 ACTIVATION | 26 | 1.39e-01 | 1.68e-01 | 2.96e-01 |
| HDMS DEMETHYLATE HISTONES | 27 | 1.31e-01 | -1.68e-01 | 2.86e-01 |
| RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 59 | 2.61e-02 | 1.68e-01 | 9.03e-02 |
| ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES | 49 | 4.42e-02 | -1.66e-01 | 1.32e-01 |
| PLASMA LIPOPROTEIN ASSEMBLY | 11 | 3.41e-01 | 1.66e-01 | 5.17e-01 |
| SIGNALING BY FGFR1 IN DISEASE | 32 | 1.06e-01 | 1.65e-01 | 2.46e-01 |
| RND3 GTPASE CYCLE | 38 | 7.86e-02 | -1.65e-01 | 2.00e-01 |
| REGULATION OF TP53 EXPRESSION AND DEGRADATION | 34 | 9.82e-02 | 1.64e-01 | 2.35e-01 |
| SIGNALING BY VEGF | 102 | 4.38e-03 | 1.63e-01 | 2.27e-02 |
| FORMATION OF INCISION COMPLEX IN GG NER | 43 | 6.39e-02 | 1.63e-01 | 1.74e-01 |
| AURKA ACTIVATION BY TPX2 | 71 | 1.74e-02 | -1.63e-01 | 6.88e-02 |
| UPTAKE AND ACTIONS OF BACTERIAL TOXINS | 29 | 1.29e-01 | 1.63e-01 | 2.82e-01 |
| G2 M CHECKPOINTS | 133 | 1.18e-03 | 1.63e-01 | 8.13e-03 |
| DSCAM INTERACTIONS | 11 | 3.50e-01 | -1.63e-01 | 5.25e-01 |
| POLYMERASE SWITCHING | 14 | 2.93e-01 | 1.62e-01 | 4.72e-01 |
| NCAM SIGNALING FOR NEURITE OUT GROWTH | 59 | 3.10e-02 | -1.62e-01 | 1.02e-01 |
| AMYLOID FIBER FORMATION | 56 | 3.56e-02 | 1.62e-01 | 1.11e-01 |
| TCF DEPENDENT SIGNALING IN RESPONSE TO WNT | 177 | 1.97e-04 | 1.62e-01 | 1.83e-03 |
| TOLL LIKE RECEPTOR CASCADES | 137 | 1.05e-03 | 1.62e-01 | 7.49e-03 |
| METABOLISM OF CARBOHYDRATES | 258 | 7.50e-06 | 1.62e-01 | 1.31e-04 |
| RUNX3 REGULATES NOTCH SIGNALING | 13 | 3.12e-01 | -1.62e-01 | 4.88e-01 |
| SIGNALING BY FGFR IN DISEASE | 55 | 3.79e-02 | 1.62e-01 | 1.17e-01 |
| PROCESSIVE SYNTHESIS ON THE LAGGING STRAND | 15 | 2.80e-01 | 1.61e-01 | 4.59e-01 |
| NEGATIVE REGULATION OF MET ACTIVITY | 21 | 2.01e-01 | 1.61e-01 | 3.79e-01 |
| DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE | 27 | 1.47e-01 | 1.61e-01 | 3.10e-01 |
| REPRESSION OF WNT TARGET GENES | 14 | 2.97e-01 | 1.61e-01 | 4.74e-01 |
| APOPTOTIC FACTOR MEDIATED RESPONSE | 18 | 2.39e-01 | 1.60e-01 | 4.17e-01 |
| AUTOPHAGY | 138 | 1.17e-03 | 1.60e-01 | 8.09e-03 |
| CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE | 49 | 5.26e-02 | 1.60e-01 | 1.49e-01 |
| SIGNALING BY TGFB FAMILY MEMBERS | 96 | 6.81e-03 | 1.60e-01 | 3.22e-02 |
| LATE ENDOSOMAL MICROAUTOPHAGY | 31 | 1.25e-01 | 1.59e-01 | 2.78e-01 |
| SELECTIVE AUTOPHAGY | 72 | 1.99e-02 | 1.59e-01 | 7.51e-02 |
| CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION | 21 | 2.08e-01 | 1.59e-01 | 3.84e-01 |
| METAL ION SLC TRANSPORTERS | 24 | 1.79e-01 | 1.58e-01 | 3.55e-01 |
| ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA | 15 | 2.88e-01 | 1.58e-01 | 4.67e-01 |
| CELLULAR RESPONSES TO EXTERNAL STIMULI | 597 | 5.35e-11 | 1.58e-01 | 3.12e-09 |
| MET ACTIVATES PTK2 SIGNALING | 29 | 1.42e-01 | -1.58e-01 | 3.03e-01 |
| PEPTIDE HORMONE METABOLISM | 58 | 3.80e-02 | 1.58e-01 | 1.17e-01 |
| NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS | 21 | 2.11e-01 | 1.58e-01 | 3.87e-01 |
| KSRP KHSRP BINDS AND DESTABILIZES MRNA | 16 | 2.75e-01 | -1.58e-01 | 4.53e-01 |
| TRANSLESION SYNTHESIS BY POLK | 17 | 2.61e-01 | 1.57e-01 | 4.39e-01 |
| CHROMATIN MODIFYING ENZYMES | 217 | 6.62e-05 | -1.57e-01 | 7.29e-04 |
| HDACS DEACETYLATE HISTONES | 45 | 6.81e-02 | -1.57e-01 | 1.83e-01 |
| RHO GTPASES ACTIVATE PAKS | 21 | 2.13e-01 | 1.57e-01 | 3.89e-01 |
| BASIGIN INTERACTIONS | 22 | 2.04e-01 | 1.57e-01 | 3.80e-01 |
| NUCLEOBASE CATABOLISM | 31 | 1.32e-01 | 1.56e-01 | 2.87e-01 |
| RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | 85 | 1.29e-02 | -1.56e-01 | 5.40e-02 |
| INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | 13 | 3.30e-01 | 1.56e-01 | 5.07e-01 |
| P75NTR REGULATES AXONOGENESIS | 10 | 3.95e-01 | 1.55e-01 | 5.62e-01 |
| SIGNALING BY ERBB4 | 57 | 4.27e-02 | 1.55e-01 | 1.28e-01 |
| RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES | 78 | 1.79e-02 | -1.55e-01 | 7.00e-02 |
| MTORC1 MEDIATED SIGNALLING | 24 | 1.89e-01 | 1.55e-01 | 3.66e-01 |
| INTERLEUKIN 37 SIGNALING | 19 | 2.45e-01 | 1.54e-01 | 4.22e-01 |
| RHOG GTPASE CYCLE | 73 | 2.34e-02 | 1.53e-01 | 8.49e-02 |
| FERTILIZATION | 12 | 3.58e-01 | -1.53e-01 | 5.29e-01 |
| BETA CATENIN INDEPENDENT WNT SIGNALING | 138 | 1.91e-03 | 1.53e-01 | 1.21e-02 |
| NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | 12 | 3.58e-01 | 1.53e-01 | 5.29e-01 |
| CLASS A 1 RHODOPSIN LIKE RECEPTORS | 178 | 4.33e-04 | 1.53e-01 | 3.63e-03 |
| SIGNALING BY TGF BETA RECEPTOR COMPLEX | 72 | 2.48e-02 | 1.53e-01 | 8.75e-02 |
| NRAGE SIGNALS DEATH THROUGH JNK | 56 | 4.76e-02 | -1.53e-01 | 1.39e-01 |
| REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS | 13 | 3.40e-01 | -1.53e-01 | 5.16e-01 |
| NEDDYLATION | 216 | 1.11e-04 | 1.53e-01 | 1.13e-03 |
| ACYL CHAIN REMODELLING OF PE | 16 | 2.91e-01 | 1.52e-01 | 4.71e-01 |
| PROTEIN FOLDING | 88 | 1.38e-02 | 1.52e-01 | 5.72e-02 |
| RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA | 24 | 1.98e-01 | -1.52e-01 | 3.76e-01 |
| SIGNALING BY WNT | 266 | 2.10e-05 | 1.52e-01 | 2.95e-04 |
| PLATELET AGGREGATION PLUG FORMATION | 33 | 1.34e-01 | 1.51e-01 | 2.90e-01 |
| NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 2.82e-01 | -1.51e-01 | 4.60e-01 |
| DISEASES OF DNA REPAIR | 11 | 3.87e-01 | -1.51e-01 | 5.57e-01 |
| STIMULI SENSING CHANNELS | 74 | 2.53e-02 | -1.51e-01 | 8.85e-02 |
| SYNTHESIS OF PE | 12 | 3.67e-01 | -1.50e-01 | 5.39e-01 |
| ELEVATION OF CYTOSOLIC CA2 LEVELS | 14 | 3.30e-01 | -1.50e-01 | 5.07e-01 |
| CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | 12 | 3.69e-01 | -1.50e-01 | 5.40e-01 |
| PECAM1 INTERACTIONS | 12 | 3.70e-01 | 1.50e-01 | 5.40e-01 |
| TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS | 12 | 3.70e-01 | 1.49e-01 | 5.40e-01 |
| HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR | 48 | 7.39e-02 | 1.49e-01 | 1.93e-01 |
| REGULATION OF IFNG SIGNALING | 13 | 3.52e-01 | 1.49e-01 | 5.28e-01 |
| SIGNALING BY PDGFR IN DISEASE | 20 | 2.50e-01 | 1.48e-01 | 4.28e-01 |
| GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK | 16 | 3.04e-01 | 1.48e-01 | 4.82e-01 |
| TP53 REGULATES METABOLIC GENES | 84 | 1.89e-02 | 1.48e-01 | 7.30e-02 |
| METABOLISM OF NUCLEOTIDES | 91 | 1.47e-02 | 1.48e-01 | 6.02e-02 |
| COLLAGEN DEGRADATION | 49 | 7.42e-02 | -1.47e-01 | 1.93e-01 |
| SIGNALING BY ERBB2 | 48 | 8.00e-02 | 1.46e-01 | 2.02e-01 |
| NEGATIVE REGULATION OF MAPK PATHWAY | 43 | 9.86e-02 | 1.46e-01 | 2.35e-01 |
| DISEASES OF IMMUNE SYSTEM | 23 | 2.28e-01 | 1.45e-01 | 4.06e-01 |
| ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION | 14 | 3.48e-01 | 1.45e-01 | 5.24e-01 |
| AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | 14 | 3.51e-01 | 1.44e-01 | 5.27e-01 |
| BASE EXCISION REPAIR AP SITE FORMATION | 29 | 1.81e-01 | -1.44e-01 | 3.57e-01 |
| SIGNALING BY PTK6 | 50 | 8.02e-02 | 1.43e-01 | 2.02e-01 |
| LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME | 13 | 3.72e-01 | -1.43e-01 | 5.43e-01 |
| SIALIC ACID METABOLISM | 32 | 1.63e-01 | 1.42e-01 | 3.30e-01 |
| MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS | 18 | 2.96e-01 | -1.42e-01 | 4.73e-01 |
| SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | 18 | 2.96e-01 | -1.42e-01 | 4.73e-01 |
| UNFOLDED PROTEIN RESPONSE UPR | 85 | 2.37e-02 | 1.42e-01 | 8.55e-02 |
| OLFACTORY SIGNALING PATHWAY | 23 | 2.40e-01 | 1.42e-01 | 4.18e-01 |
| JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | 22 | 2.51e-01 | 1.42e-01 | 4.28e-01 |
| LONG TERM POTENTIATION | 23 | 2.41e-01 | -1.41e-01 | 4.18e-01 |
| SIGNALING BY FGFR2 | 64 | 5.11e-02 | 1.41e-01 | 1.45e-01 |
| INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | 28 | 1.97e-01 | 1.41e-01 | 3.75e-01 |
| REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | 29 | 1.91e-01 | -1.40e-01 | 3.67e-01 |
| LYSOSPHINGOLIPID AND LPA RECEPTORS | 12 | 4.00e-01 | 1.40e-01 | 5.68e-01 |
| LEISHMANIA INFECTION | 193 | 7.86e-04 | 1.40e-01 | 5.80e-03 |
| TRANSCRIPTIONAL REGULATION BY VENTX | 35 | 1.52e-01 | -1.40e-01 | 3.16e-01 |
| DOWNSTREAM SIGNAL TRANSDUCTION | 29 | 1.92e-01 | 1.40e-01 | 3.68e-01 |
| NR1H2 AND NR1H3 MEDIATED SIGNALING | 38 | 1.36e-01 | -1.40e-01 | 2.93e-01 |
| PKA ACTIVATION IN GLUCAGON SIGNALLING | 16 | 3.35e-01 | 1.39e-01 | 5.11e-01 |
| IRAK1 RECRUITS IKK COMPLEX | 14 | 3.67e-01 | 1.39e-01 | 5.39e-01 |
| GPCR LIGAND BINDING | 259 | 1.18e-04 | 1.39e-01 | 1.16e-03 |
| APC CDC20 MEDIATED DEGRADATION OF NEK2A | 24 | 2.38e-01 | 1.39e-01 | 4.17e-01 |
| RA BIOSYNTHESIS PATHWAY | 12 | 4.04e-01 | 1.39e-01 | 5.72e-01 |
| SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION | 24 | 2.39e-01 | 1.39e-01 | 4.17e-01 |
| ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 3.22e-01 | -1.39e-01 | 4.99e-01 |
| SURFACTANT METABOLISM | 16 | 3.37e-01 | 1.39e-01 | 5.14e-01 |
| NGF STIMULATED TRANSCRIPTION | 37 | 1.46e-01 | 1.38e-01 | 3.08e-01 |
| INTERLEUKIN 35 SIGNALLING | 10 | 4.50e-01 | 1.38e-01 | 6.12e-01 |
| TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE | 17 | 3.25e-01 | -1.38e-01 | 5.02e-01 |
| APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B | 21 | 2.75e-01 | 1.38e-01 | 4.53e-01 |
| ADENYLATE CYCLASE ACTIVATING PATHWAY | 10 | 4.53e-01 | -1.37e-01 | 6.14e-01 |
| EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS | 31 | 1.87e-01 | -1.37e-01 | 3.65e-01 |
| NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS | 53 | 8.55e-02 | 1.37e-01 | 2.11e-01 |
| HEMOSTASIS | 471 | 4.13e-07 | 1.37e-01 | 1.21e-05 |
| CD28 CO STIMULATION | 29 | 2.04e-01 | 1.36e-01 | 3.80e-01 |
| THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION | 14 | 3.80e-01 | 1.36e-01 | 5.50e-01 |
| TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES | 61 | 6.79e-02 | -1.35e-01 | 1.83e-01 |
| HS GAG BIOSYNTHESIS | 29 | 2.08e-01 | 1.35e-01 | 3.84e-01 |
| FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES | 24 | 2.52e-01 | 1.35e-01 | 4.29e-01 |
| MET ACTIVATES RAS SIGNALING | 10 | 4.61e-01 | 1.35e-01 | 6.20e-01 |
| RIPK1 MEDIATED REGULATED NECROSIS | 25 | 2.44e-01 | 1.35e-01 | 4.21e-01 |
| CYTOCHROME C MEDIATED APOPTOTIC RESPONSE | 12 | 4.19e-01 | 1.35e-01 | 5.84e-01 |
| RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | 28 | 2.18e-01 | -1.34e-01 | 3.94e-01 |
| CELL CYCLE CHECKPOINTS | 241 | 3.32e-04 | 1.34e-01 | 2.93e-03 |
| ASPARAGINE N LINKED GLYCOSYLATION | 283 | 1.08e-04 | 1.34e-01 | 1.11e-03 |
| SIGNALING BY EGFR | 47 | 1.12e-01 | 1.34e-01 | 2.56e-01 |
| DNA DAMAGE RECOGNITION IN GG NER | 38 | 1.53e-01 | 1.34e-01 | 3.18e-01 |
| TRANSCRIPTIONAL REGULATION BY MECP2 | 60 | 7.31e-02 | -1.34e-01 | 1.92e-01 |
| DNA STRAND ELONGATION | 32 | 1.90e-01 | 1.34e-01 | 3.67e-01 |
| TIGHT JUNCTION INTERACTIONS | 18 | 3.26e-01 | 1.34e-01 | 5.03e-01 |
| SUMOYLATION OF IMMUNE RESPONSE PROTEINS | 11 | 4.43e-01 | 1.34e-01 | 6.06e-01 |
| CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | 34 | 1.78e-01 | 1.33e-01 | 3.54e-01 |
| GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER | 83 | 3.66e-02 | 1.33e-01 | 1.14e-01 |
| ADAPTIVE IMMUNE SYSTEM | 594 | 3.68e-08 | 1.33e-01 | 1.48e-06 |
| SIGNALING BY FGFR | 74 | 4.96e-02 | 1.32e-01 | 1.43e-01 |
| VITAMIN B5 PANTOTHENATE METABOLISM | 14 | 3.93e-01 | 1.32e-01 | 5.62e-01 |
| RHO GTPASES ACTIVATE IQGAPS | 24 | 2.65e-01 | 1.32e-01 | 4.42e-01 |
| NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING | 33 | 1.91e-01 | 1.31e-01 | 3.68e-01 |
| RND2 GTPASE CYCLE | 38 | 1.62e-01 | -1.31e-01 | 3.28e-01 |
| CLATHRIN MEDIATED ENDOCYTOSIS | 133 | 9.18e-03 | 1.31e-01 | 4.14e-02 |
| TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS | 43 | 1.38e-01 | 1.31e-01 | 2.96e-01 |
| DEGRADATION OF THE EXTRACELLULAR MATRIX | 105 | 2.10e-02 | -1.30e-01 | 7.76e-02 |
| HEDGEHOG OFF STATE | 106 | 2.05e-02 | 1.30e-01 | 7.66e-02 |
| CARGO CONCENTRATION IN THE ER | 31 | 2.11e-01 | 1.30e-01 | 3.87e-01 |
| NEGATIVE REGULATION OF THE PI3K AKT NETWORK | 93 | 3.12e-02 | 1.29e-01 | 1.02e-01 |
| HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE | 40 | 1.58e-01 | -1.29e-01 | 3.24e-01 |
| MATURATION OF NUCLEOPROTEIN | 10 | 4.81e-01 | -1.29e-01 | 6.37e-01 |
| AMINE LIGAND BINDING RECEPTORS | 31 | 2.16e-01 | 1.28e-01 | 3.92e-01 |
| DEFECTS IN COBALAMIN B12 METABOLISM | 12 | 4.41e-01 | 1.28e-01 | 6.05e-01 |
| CONSTITUTIVE SIGNALING BY EGFRVIII | 15 | 3.91e-01 | 1.28e-01 | 5.60e-01 |
| CAMK IV MEDIATED PHOSPHORYLATION OF CREB | 10 | 4.85e-01 | -1.27e-01 | 6.40e-01 |
| TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX | 30 | 2.28e-01 | 1.27e-01 | 4.06e-01 |
| ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS | 22 | 3.02e-01 | 1.27e-01 | 4.80e-01 |
| REGULATION OF IFNA SIGNALING | 12 | 4.46e-01 | -1.27e-01 | 6.08e-01 |
| ACYL CHAIN REMODELLING OF PG | 10 | 4.88e-01 | 1.27e-01 | 6.42e-01 |
| ELASTIC FIBRE FORMATION | 36 | 1.89e-01 | 1.27e-01 | 3.66e-01 |
| CLASS B 2 SECRETIN FAMILY RECEPTORS | 69 | 6.92e-02 | 1.27e-01 | 1.85e-01 |
| MRNA SPLICING | 188 | 2.82e-03 | 1.26e-01 | 1.63e-02 |
| DEUBIQUITINATION | 240 | 7.54e-04 | 1.26e-01 | 5.71e-03 |
| SIGNALING BY LEPTIN | 10 | 4.89e-01 | -1.26e-01 | 6.43e-01 |
| ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION | 114 | 1.99e-02 | 1.26e-01 | 7.51e-02 |
| ERBB2 ACTIVATES PTK6 SIGNALING | 11 | 4.69e-01 | -1.26e-01 | 6.26e-01 |
| INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING | 41 | 1.63e-01 | 1.26e-01 | 3.29e-01 |
| CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION | 341 | 6.61e-05 | 1.26e-01 | 7.29e-04 |
| PROCESSING OF SMDT1 | 16 | 3.83e-01 | 1.26e-01 | 5.55e-01 |
| ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION | 90 | 3.96e-02 | 1.26e-01 | 1.22e-01 |
| RHO GTPASE EFFECTORS | 247 | 6.98e-04 | 1.25e-01 | 5.43e-03 |
| CYCLIN D ASSOCIATED EVENTS IN G1 | 45 | 1.46e-01 | 1.25e-01 | 3.08e-01 |
| PROTEIN PROTEIN INTERACTIONS AT SYNAPSES | 85 | 4.61e-02 | -1.25e-01 | 1.37e-01 |
| OTHER SEMAPHORIN INTERACTIONS | 19 | 3.45e-01 | -1.25e-01 | 5.22e-01 |
| NUCLEAR PORE COMPLEX NPC DISASSEMBLY | 31 | 2.29e-01 | -1.25e-01 | 4.07e-01 |
| RHOV GTPASE CYCLE | 32 | 2.22e-01 | -1.25e-01 | 4.00e-01 |
| O LINKED GLYCOSYLATION | 85 | 4.79e-02 | -1.24e-01 | 1.39e-01 |
| AMINO ACIDS REGULATE MTORC1 | 51 | 1.25e-01 | 1.24e-01 | 2.78e-01 |
| TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS | 31 | 2.33e-01 | 1.24e-01 | 4.13e-01 |
| MITOTIC TELOPHASE CYTOKINESIS | 13 | 4.41e-01 | 1.23e-01 | 6.05e-01 |
| PROCESSING OF INTRONLESS PRE MRNAS | 19 | 3.54e-01 | -1.23e-01 | 5.28e-01 |
| SIGNALING BY MET | 75 | 6.63e-02 | 1.23e-01 | 1.79e-01 |
| CILIUM ASSEMBLY | 189 | 3.67e-03 | -1.23e-01 | 1.98e-02 |
| CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING | 28 | 2.63e-01 | 1.22e-01 | 4.41e-01 |
| G ALPHA Q SIGNALLING EVENTS | 154 | 8.94e-03 | 1.22e-01 | 4.08e-02 |
| HDR THROUGH MMEJ ALT NHEJ | 10 | 5.04e-01 | -1.22e-01 | 6.56e-01 |
| PEPTIDE LIGAND BINDING RECEPTORS | 101 | 3.47e-02 | 1.22e-01 | 1.11e-01 |
| RHOBTB1 GTPASE CYCLE | 23 | 3.13e-01 | 1.22e-01 | 4.88e-01 |
| SIGNALING BY KIT IN DISEASE | 20 | 3.47e-01 | 1.22e-01 | 5.23e-01 |
| TRAFFICKING OF AMPA RECEPTORS | 31 | 2.41e-01 | -1.22e-01 | 4.18e-01 |
| SIGNAL TRANSDUCTION BY L1 | 21 | 3.35e-01 | 1.22e-01 | 5.11e-01 |
| NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION | 59 | 1.07e-01 | 1.22e-01 | 2.47e-01 |
| ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | 37 | 2.03e-01 | 1.21e-01 | 3.80e-01 |
| NS1 MEDIATED EFFECTS ON HOST PATHWAYS | 37 | 2.04e-01 | -1.21e-01 | 3.80e-01 |
| OVARIAN TUMOR DOMAIN PROTEASES | 36 | 2.11e-01 | 1.20e-01 | 3.87e-01 |
| NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | 20 | 3.56e-01 | -1.19e-01 | 5.29e-01 |
| METABOLISM OF LIPIDS | 608 | 6.27e-07 | 1.19e-01 | 1.78e-05 |
| RORA ACTIVATES GENE EXPRESSION | 18 | 3.84e-01 | -1.18e-01 | 5.55e-01 |
| INTERLEUKIN 27 SIGNALING | 10 | 5.18e-01 | 1.18e-01 | 6.68e-01 |
| SIGNALING BY NUCLEAR RECEPTORS | 219 | 2.75e-03 | 1.18e-01 | 1.61e-02 |
| PLATELET HOMEOSTASIS | 76 | 7.80e-02 | 1.17e-01 | 1.99e-01 |
| RHOJ GTPASE CYCLE | 54 | 1.38e-01 | 1.17e-01 | 2.96e-01 |
| TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST | 15 | 4.35e-01 | -1.16e-01 | 5.98e-01 |
| CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN | 34 | 2.40e-01 | -1.16e-01 | 4.18e-01 |
| GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | 23 | 3.35e-01 | -1.16e-01 | 5.11e-01 |
| CYTOKINE SIGNALING IN IMMUNE SYSTEM | 537 | 4.49e-06 | 1.16e-01 | 8.88e-05 |
| RAB GEFS EXCHANGE GTP FOR GDP ON RABS | 87 | 6.17e-02 | 1.16e-01 | 1.68e-01 |
| RNA POLYMERASE III TRANSCRIPTION | 41 | 2.01e-01 | -1.16e-01 | 3.79e-01 |
| DCC MEDIATED ATTRACTIVE SIGNALING | 14 | 4.57e-01 | 1.15e-01 | 6.16e-01 |
| COPII MEDIATED VESICLE TRANSPORT | 66 | 1.07e-01 | 1.15e-01 | 2.48e-01 |
| DEFECTS IN VITAMIN AND COFACTOR METABOLISM | 20 | 3.75e-01 | 1.15e-01 | 5.45e-01 |
| TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS | 41 | 2.06e-01 | -1.14e-01 | 3.82e-01 |
| SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | 62 | 1.21e-01 | 1.14e-01 | 2.71e-01 |
| NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 12 | 4.95e-01 | 1.14e-01 | 6.49e-01 |
| CELLULAR HEXOSE TRANSPORT | 11 | 5.13e-01 | -1.14e-01 | 6.65e-01 |
| SIGNALING BY NODAL | 15 | 4.46e-01 | 1.14e-01 | 6.08e-01 |
| DUAL INCISION IN GG NER | 40 | 2.15e-01 | 1.13e-01 | 3.92e-01 |
| TBC RABGAPS | 43 | 2.00e-01 | 1.13e-01 | 3.78e-01 |
| METABOLISM OF RNA | 643 | 1.20e-06 | 1.13e-01 | 3.04e-05 |
| ACTIVATION OF THE PRE REPLICATIVE COMPLEX | 29 | 2.94e-01 | 1.13e-01 | 4.72e-01 |
| TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA | 34 | 2.57e-01 | -1.12e-01 | 4.35e-01 |
| REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS | 12 | 5.02e-01 | 1.12e-01 | 6.54e-01 |
| INTEGRATION OF ENERGY METABOLISM | 98 | 5.57e-02 | 1.12e-01 | 1.56e-01 |
| NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION | 21 | 3.77e-01 | -1.11e-01 | 5.47e-01 |
| EGFR DOWNREGULATION | 28 | 3.09e-01 | 1.11e-01 | 4.84e-01 |
| TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER | 77 | 9.21e-02 | 1.11e-01 | 2.24e-01 |
| MAPK FAMILY SIGNALING CASCADES | 287 | 1.23e-03 | 1.11e-01 | 8.35e-03 |
| ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING | 21 | 3.78e-01 | 1.11e-01 | 5.48e-01 |
| A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | 26 | 3.28e-01 | -1.11e-01 | 5.06e-01 |
| SYNTHESIS OF PA | 29 | 3.03e-01 | 1.10e-01 | 4.81e-01 |
| RESOLUTION OF SISTER CHROMATID COHESION | 100 | 5.71e-02 | 1.10e-01 | 1.58e-01 |
| RND1 GTPASE CYCLE | 38 | 2.41e-01 | -1.10e-01 | 4.18e-01 |
| EPH EPHRIN SIGNALING | 90 | 7.19e-02 | 1.10e-01 | 1.89e-01 |
| DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM | 39 | 2.36e-01 | 1.10e-01 | 4.16e-01 |
| IRE1ALPHA ACTIVATES CHAPERONES | 49 | 1.84e-01 | 1.10e-01 | 3.61e-01 |
| NEGATIVE REGULATION OF FLT3 | 14 | 4.79e-01 | -1.09e-01 | 6.35e-01 |
| BIOTIN TRANSPORT AND METABOLISM | 11 | 5.30e-01 | 1.09e-01 | 6.78e-01 |
| TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE | 63 | 1.35e-01 | 1.09e-01 | 2.91e-01 |
| ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS | 18 | 4.23e-01 | -1.09e-01 | 5.87e-01 |
| GLUCOSE METABOLISM | 80 | 9.24e-02 | 1.09e-01 | 2.24e-01 |
| TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | 31 | 2.94e-01 | 1.09e-01 | 4.72e-01 |
| SIGNALING BY ERBB2 IN CANCER | 25 | 3.47e-01 | 1.09e-01 | 5.23e-01 |
| MOLECULES ASSOCIATED WITH ELASTIC FIBRES | 32 | 2.88e-01 | 1.09e-01 | 4.67e-01 |
| ASSEMBLY OF THE HIV VIRION | 16 | 4.54e-01 | 1.08e-01 | 6.14e-01 |
| DOWNREGULATION OF ERBB2 SIGNALING | 28 | 3.23e-01 | 1.08e-01 | 5.00e-01 |
| TRNA PROCESSING | 105 | 5.62e-02 | -1.08e-01 | 1.57e-01 |
| ZINC TRANSPORTERS | 15 | 4.69e-01 | 1.08e-01 | 6.26e-01 |
| CHOLESTEROL BIOSYNTHESIS | 24 | 3.61e-01 | 1.08e-01 | 5.32e-01 |
| FREE FATTY ACIDS REGULATE INSULIN SECRETION | 10 | 5.55e-01 | 1.08e-01 | 6.98e-01 |
| GLYCOSAMINOGLYCAN METABOLISM | 114 | 4.69e-02 | 1.08e-01 | 1.38e-01 |
| DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | 38 | 2.53e-01 | 1.07e-01 | 4.29e-01 |
| RETROGRADE NEUROTROPHIN SIGNALLING | 14 | 4.89e-01 | 1.07e-01 | 6.43e-01 |
| PLATELET CALCIUM HOMEOSTASIS | 25 | 3.56e-01 | -1.07e-01 | 5.29e-01 |
| MYD88 INDEPENDENT TLR4 CASCADE | 93 | 7.63e-02 | 1.06e-01 | 1.97e-01 |
| TRANSPORT OF SMALL MOLECULES | 566 | 1.76e-05 | 1.06e-01 | 2.60e-04 |
| SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | 11 | 5.43e-01 | 1.06e-01 | 6.89e-01 |
| ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 | 21 | 4.01e-01 | 1.06e-01 | 5.69e-01 |
| BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | 76 | 1.11e-01 | 1.06e-01 | 2.54e-01 |
| ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS | 35 | 2.81e-01 | -1.05e-01 | 4.60e-01 |
| FGFR1 MUTANT RECEPTOR ACTIVATION | 25 | 3.63e-01 | 1.05e-01 | 5.35e-01 |
| FANCONI ANEMIA PATHWAY | 36 | 2.76e-01 | -1.05e-01 | 4.54e-01 |
| CARNITINE METABOLISM | 14 | 4.97e-01 | 1.05e-01 | 6.50e-01 |
| NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | 43 | 2.37e-01 | -1.04e-01 | 4.16e-01 |
| YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | 10 | 5.69e-01 | 1.04e-01 | 7.08e-01 |
| DUAL INCISION IN TC NER | 64 | 1.54e-01 | 1.03e-01 | 3.19e-01 |
| PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE | 49 | 2.15e-01 | 1.02e-01 | 3.92e-01 |
| MICRORNA MIRNA BIOGENESIS | 24 | 3.86e-01 | -1.02e-01 | 5.56e-01 |
| RECYCLING PATHWAY OF L1 | 40 | 2.66e-01 | 1.02e-01 | 4.44e-01 |
| REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION | 30 | 3.38e-01 | -1.01e-01 | 5.15e-01 |
| FORMATION OF TC NER PRE INCISION COMPLEX | 53 | 2.06e-01 | 1.01e-01 | 3.81e-01 |
| AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | 25 | 3.84e-01 | -1.00e-01 | 5.55e-01 |
| FORMATION OF THE CORNIFIED ENVELOPE | 28 | 3.58e-01 | -1.00e-01 | 5.29e-01 |
| KERATINIZATION | 28 | 3.58e-01 | -1.00e-01 | 5.29e-01 |
| NUCLEOTIDE EXCISION REPAIR | 109 | 7.04e-02 | 1.00e-01 | 1.87e-01 |
| ESR MEDIATED SIGNALING | 163 | 2.81e-02 | 9.98e-02 | 9.54e-02 |
| POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | 59 | 1.86e-01 | -9.96e-02 | 3.63e-01 |
| TOLL LIKE RECEPTOR 9 TLR9 CASCADE | 91 | 1.01e-01 | 9.94e-02 | 2.39e-01 |
| ERK MAPK TARGETS | 22 | 4.24e-01 | 9.85e-02 | 5.87e-01 |
| HIV TRANSCRIPTION INITIATION | 45 | 2.56e-01 | 9.79e-02 | 4.34e-01 |
| TNFR1 INDUCED PROAPOPTOTIC SIGNALING | 12 | 5.58e-01 | 9.76e-02 | 6.99e-01 |
| REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION | 10 | 5.94e-01 | 9.75e-02 | 7.26e-01 |
| MITOTIC SPINDLE CHECKPOINT | 96 | 9.91e-02 | 9.75e-02 | 2.35e-01 |
| POTENTIAL THERAPEUTICS FOR SARS | 76 | 1.42e-01 | 9.74e-02 | 3.03e-01 |
| ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS | 23 | 4.20e-01 | 9.73e-02 | 5.84e-01 |
| REGULATION OF INSULIN SECRETION | 71 | 1.58e-01 | 9.69e-02 | 3.25e-01 |
| COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 44 | 2.66e-01 | 9.68e-02 | 4.44e-01 |
| P75NTR RECRUITS SIGNALLING COMPLEXES | 13 | 5.46e-01 | 9.68e-02 | 6.91e-01 |
| ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | 284 | 5.16e-03 | 9.66e-02 | 2.58e-02 |
| REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION | 84 | 1.26e-01 | -9.66e-02 | 2.78e-01 |
| METABOLISM OF STEROIDS | 111 | 8.05e-02 | 9.61e-02 | 2.03e-01 |
| RAC2 GTPASE CYCLE | 86 | 1.26e-01 | 9.56e-02 | 2.78e-01 |
| INSULIN PROCESSING | 24 | 4.23e-01 | 9.45e-02 | 5.87e-01 |
| SIGNALING BY HEDGEHOG | 141 | 5.30e-02 | 9.45e-02 | 1.50e-01 |
| INTRINSIC PATHWAY FOR APOPTOSIS | 50 | 2.52e-01 | 9.36e-02 | 4.29e-01 |
| STRIATED MUSCLE CONTRACTION | 26 | 4.10e-01 | -9.34e-02 | 5.76e-01 |
| RHO GTPASES ACTIVATE FORMINS | 118 | 8.05e-02 | 9.32e-02 | 2.03e-01 |
| TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE | 92 | 1.26e-01 | 9.25e-02 | 2.78e-01 |
| NEUROTRANSMITTER RELEASE CYCLE | 48 | 2.69e-01 | 9.23e-02 | 4.46e-01 |
| EFFECTS OF PIP2 HYDROLYSIS | 27 | 4.07e-01 | -9.22e-02 | 5.74e-01 |
| POST TRANSLATIONAL PROTEIN MODIFICATION | 1206 | 9.30e-08 | 9.22e-02 | 3.22e-06 |
| G PROTEIN MEDIATED EVENTS | 52 | 2.52e-01 | 9.19e-02 | 4.29e-01 |
| NERVOUS SYSTEM DEVELOPMENT | 546 | 2.52e-04 | 9.19e-02 | 2.28e-03 |
| DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS | 365 | 2.63e-03 | 9.19e-02 | 1.54e-02 |
| ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS | 66 | 1.97e-01 | -9.18e-02 | 3.75e-01 |
| NUCLEAR IMPORT OF REV PROTEIN | 32 | 3.69e-01 | -9.17e-02 | 5.40e-01 |
| SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS | 41 | 3.10e-01 | 9.17e-02 | 4.85e-01 |
| RAB REGULATION OF TRAFFICKING | 118 | 8.56e-02 | 9.17e-02 | 2.11e-01 |
| DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA | 63 | 2.09e-01 | 9.16e-02 | 3.84e-01 |
| SUMOYLATION OF DNA METHYLATION PROTEINS | 16 | 5.27e-01 | -9.14e-02 | 6.77e-01 |
| IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | 45 | 2.94e-01 | 9.05e-02 | 4.72e-01 |
| CHONDROITIN SULFATE BIOSYNTHESIS | 19 | 4.95e-01 | 9.04e-02 | 6.49e-01 |
| RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER | 28 | 4.08e-01 | -9.03e-02 | 5.75e-01 |
| PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | 237 | 1.75e-02 | 8.97e-02 | 6.91e-02 |
| ABC TRANSPORTERS IN LIPID HOMEOSTASIS | 13 | 5.77e-01 | 8.94e-02 | 7.14e-01 |
| GENE SILENCING BY RNA | 83 | 1.60e-01 | -8.93e-02 | 3.27e-01 |
| NETRIN 1 SIGNALING | 49 | 2.81e-01 | -8.91e-02 | 4.59e-01 |
| PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING | 11 | 6.10e-01 | -8.87e-02 | 7.41e-01 |
| RHO GTPASES ACTIVATE NADPH OXIDASES | 18 | 5.15e-01 | 8.87e-02 | 6.66e-01 |
| APOPTOTIC EXECUTION PHASE | 46 | 3.00e-01 | 8.84e-02 | 4.78e-01 |
| SIGNALING BY GPCR | 476 | 1.01e-03 | 8.83e-02 | 7.25e-03 |
| POST CHAPERONIN TUBULIN FOLDING PATHWAY | 17 | 5.29e-01 | -8.83e-02 | 6.78e-01 |
| TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | 169 | 4.80e-02 | 8.83e-02 | 1.39e-01 |
| P75NTR SIGNALS VIA NF KB | 16 | 5.41e-01 | 8.82e-02 | 6.89e-01 |
| HS GAG DEGRADATION | 20 | 4.96e-01 | -8.80e-02 | 6.49e-01 |
| TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE | 13 | 5.84e-01 | 8.78e-02 | 7.19e-01 |
| HCMV EARLY EVENTS | 79 | 1.84e-01 | -8.66e-02 | 3.61e-01 |
| MEMBRANE TRAFFICKING | 579 | 3.95e-04 | 8.65e-02 | 3.34e-03 |
| CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY | 23 | 4.73e-01 | 8.65e-02 | 6.30e-01 |
| REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS | 11 | 6.20e-01 | 8.64e-02 | 7.47e-01 |
| INTERLEUKIN RECEPTOR SHC SIGNALING | 20 | 5.06e-01 | 8.60e-02 | 6.57e-01 |
| INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | 19 | 5.18e-01 | 8.56e-02 | 6.68e-01 |
| SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS | 57 | 2.64e-01 | -8.56e-02 | 4.41e-01 |
| SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER | 15 | 5.69e-01 | -8.48e-02 | 7.08e-01 |
| ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS | 17 | 5.45e-01 | -8.47e-02 | 6.91e-01 |
| CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | 49 | 3.05e-01 | 8.47e-02 | 4.83e-01 |
| SIGNALING BY RECEPTOR TYROSINE KINASES | 463 | 2.10e-03 | 8.37e-02 | 1.29e-02 |
| OXIDATIVE STRESS INDUCED SENESCENCE | 78 | 2.02e-01 | -8.36e-02 | 3.79e-01 |
| LYSINE CATABOLISM | 11 | 6.32e-01 | 8.33e-02 | 7.55e-01 |
| SHC1 EVENTS IN ERBB4 SIGNALING | 13 | 6.03e-01 | 8.33e-02 | 7.35e-01 |
| PTEN REGULATION | 134 | 9.63e-02 | 8.33e-02 | 2.31e-01 |
| SIGNALING BY FLT3 FUSION PROTEINS | 18 | 5.41e-01 | -8.31e-02 | 6.89e-01 |
| SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER | 59 | 2.71e-01 | -8.29e-02 | 4.48e-01 |
| SIGNALING BY NTRKS | 131 | 1.03e-01 | 8.25e-02 | 2.41e-01 |
| HATS ACETYLATE HISTONES | 91 | 1.75e-01 | -8.24e-02 | 3.50e-01 |
| NUCLEAR ENVELOPE NE REASSEMBLY | 63 | 2.61e-01 | 8.20e-02 | 4.39e-01 |
| SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | 15 | 5.83e-01 | -8.19e-02 | 7.19e-01 |
| MYOGENESIS | 25 | 4.79e-01 | -8.18e-02 | 6.36e-01 |
| TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS | 28 | 4.55e-01 | 8.17e-02 | 6.15e-01 |
| HIV LIFE CYCLE | 143 | 9.23e-02 | 8.16e-02 | 2.24e-01 |
| DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE | 43 | 3.55e-01 | -8.16e-02 | 5.29e-01 |
| PRE NOTCH EXPRESSION AND PROCESSING | 63 | 2.64e-01 | -8.14e-02 | 4.41e-01 |
| COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM | 13 | 6.12e-01 | 8.13e-02 | 7.42e-01 |
| CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | 19 | 5.40e-01 | 8.13e-02 | 6.88e-01 |
| CONDENSATION OF PROPHASE CHROMOSOMES | 27 | 4.65e-01 | 8.12e-02 | 6.23e-01 |
| VESICLE MEDIATED TRANSPORT | 607 | 6.75e-04 | 8.12e-02 | 5.29e-03 |
| SODIUM CALCIUM EXCHANGERS | 10 | 6.66e-01 | 7.90e-02 | 7.84e-01 |
| TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS | 54 | 3.18e-01 | -7.87e-02 | 4.94e-01 |
| TNF SIGNALING | 43 | 3.75e-01 | 7.82e-02 | 5.45e-01 |
| ECM PROTEOGLYCANS | 64 | 2.81e-01 | -7.80e-02 | 4.59e-01 |
| METABOLISM OF VITAMINS AND COFACTORS | 148 | 1.03e-01 | 7.77e-02 | 2.41e-01 |
| REGULATION OF LIPID METABOLISM BY PPARALPHA | 107 | 1.66e-01 | -7.76e-02 | 3.34e-01 |
| RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK | 48 | 3.55e-01 | 7.72e-02 | 5.29e-01 |
| MTOR SIGNALLING | 40 | 3.99e-01 | 7.71e-02 | 5.67e-01 |
| INTRACELLULAR SIGNALING BY SECOND MESSENGERS | 281 | 2.84e-02 | 7.61e-02 | 9.60e-02 |
| SIGNALLING TO ERKS | 34 | 4.46e-01 | 7.56e-02 | 6.08e-01 |
| TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | 43 | 3.93e-01 | 7.53e-02 | 5.62e-01 |
| DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS | 18 | 5.80e-01 | 7.53e-02 | 7.18e-01 |
| INTERLEUKIN 2 FAMILY SIGNALING | 33 | 4.56e-01 | 7.50e-02 | 6.15e-01 |
| M PHASE | 336 | 1.91e-02 | 7.46e-02 | 7.31e-02 |
| POLO LIKE KINASE MEDIATED EVENTS | 13 | 6.44e-01 | 7.40e-02 | 7.65e-01 |
| SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III | 23 | 5.42e-01 | 7.35e-02 | 6.89e-01 |
| VEGFR2 MEDIATED CELL PROLIFERATION | 19 | 5.81e-01 | 7.32e-02 | 7.18e-01 |
| SUMOYLATION OF SUMOYLATION PROTEINS | 33 | 4.68e-01 | -7.30e-02 | 6.25e-01 |
| CELL CYCLE MITOTIC | 470 | 7.02e-03 | 7.28e-02 | 3.28e-02 |
| GAB1 SIGNALOSOME | 14 | 6.38e-01 | 7.27e-02 | 7.59e-01 |
| TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 | 15 | 6.26e-01 | 7.27e-02 | 7.52e-01 |
| RNA POLYMERASE III TRANSCRIPTION TERMINATION | 23 | 5.46e-01 | -7.27e-02 | 6.91e-01 |
| RUNX2 REGULATES BONE DEVELOPMENT | 29 | 5.00e-01 | 7.25e-02 | 6.52e-01 |
| SIGNALING BY FLT3 ITD AND TKD MUTANTS | 15 | 6.27e-01 | 7.24e-02 | 7.52e-01 |
| CA2 PATHWAY | 56 | 3.53e-01 | 7.18e-02 | 5.28e-01 |
| INOSITOL PHOSPHATE METABOLISM | 47 | 3.95e-01 | 7.17e-02 | 5.62e-01 |
| APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | 35 | 4.64e-01 | 7.16e-02 | 6.22e-01 |
| VIRAL MESSENGER RNA SYNTHESIS | 42 | 4.26e-01 | -7.11e-02 | 5.88e-01 |
| HDR THROUGH HOMOLOGOUS RECOMBINATION HRR | 62 | 3.34e-01 | -7.10e-02 | 5.11e-01 |
| CELL JUNCTION ORGANIZATION | 75 | 2.93e-01 | 7.02e-02 | 4.72e-01 |
| DNA REPAIR | 291 | 4.11e-02 | -6.98e-02 | 1.24e-01 |
| ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT | 23 | 5.64e-01 | 6.94e-02 | 7.05e-01 |
| RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE | 22 | 5.73e-01 | -6.94e-02 | 7.13e-01 |
| REGULATION OF TNFR1 SIGNALING | 34 | 4.85e-01 | 6.91e-02 | 6.40e-01 |
| TRAF6 MEDIATED NF KB ACTIVATION | 22 | 5.75e-01 | 6.91e-02 | 7.13e-01 |
| SUMOYLATION OF INTRACELLULAR RECEPTORS | 26 | 5.43e-01 | 6.89e-02 | 6.89e-01 |
| ION TRANSPORT BY P TYPE ATPASES | 47 | 4.18e-01 | -6.83e-02 | 5.84e-01 |
| SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | 31 | 5.12e-01 | 6.81e-02 | 6.65e-01 |
| SIGNALING BY NTRK2 TRKB | 24 | 5.65e-01 | 6.78e-02 | 7.05e-01 |
| REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE | 76 | 3.07e-01 | 6.78e-02 | 4.83e-01 |
| NEUREXINS AND NEUROLIGINS | 54 | 3.94e-01 | -6.71e-02 | 5.62e-01 |
| TRANSCRIPTION OF THE HIV GENOME | 67 | 3.43e-01 | 6.70e-02 | 5.20e-01 |
| CELLULAR SENESCENCE | 141 | 1.70e-01 | -6.69e-02 | 3.42e-01 |
| ENDOGENOUS STEROLS | 21 | 5.95e-01 | 6.69e-02 | 7.28e-01 |
| CDC42 GTPASE CYCLE | 153 | 1.54e-01 | -6.69e-02 | 3.18e-01 |
| CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY | 13 | 6.76e-01 | -6.68e-02 | 7.93e-01 |
| DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE | 20 | 6.07e-01 | -6.65e-02 | 7.38e-01 |
| NEUROTOXICITY OF CLOSTRIDIUM TOXINS | 10 | 7.17e-01 | -6.62e-02 | 8.27e-01 |
| GLYCEROPHOSPHOLIPID BIOSYNTHESIS | 107 | 2.38e-01 | 6.61e-02 | 4.17e-01 |
| TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST | 13 | 6.80e-01 | -6.61e-02 | 7.97e-01 |
| MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION | 16 | 6.50e-01 | 6.56e-02 | 7.71e-01 |
| RNA POLYMERASE III CHAIN ELONGATION | 18 | 6.32e-01 | -6.53e-02 | 7.55e-01 |
| RAC3 GTPASE CYCLE | 88 | 2.93e-01 | 6.49e-02 | 4.72e-01 |
| REGULATION OF PTEN GENE TRANSCRIPTION | 59 | 3.90e-01 | -6.48e-02 | 5.58e-01 |
| DEVELOPMENTAL BIOLOGY | 809 | 1.87e-03 | 6.47e-02 | 1.20e-02 |
| NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 23 | 5.91e-01 | -6.47e-02 | 7.24e-01 |
| DEADENYLATION DEPENDENT MRNA DECAY | 55 | 4.09e-01 | -6.43e-02 | 5.76e-01 |
| SIGNALLING TO RAS | 20 | 6.20e-01 | -6.40e-02 | 7.47e-01 |
| ACTIVATION OF AMPK DOWNSTREAM OF NMDARS | 20 | 6.22e-01 | -6.38e-02 | 7.48e-01 |
| SIGNALING BY NOTCH2 | 33 | 5.27e-01 | -6.36e-02 | 6.77e-01 |
| RNA POLYMERASE I PROMOTER ESCAPE | 47 | 4.52e-01 | 6.35e-02 | 6.14e-01 |
| REGULATION OF KIT SIGNALING | 16 | 6.61e-01 | -6.34e-02 | 7.80e-01 |
| ORGANELLE BIOGENESIS AND MAINTENANCE | 281 | 6.95e-02 | -6.31e-02 | 1.85e-01 |
| NUCLEAR ENVELOPE BREAKDOWN | 47 | 4.56e-01 | -6.29e-02 | 6.15e-01 |
| FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX | 46 | 4.62e-01 | -6.28e-02 | 6.20e-01 |
| NUCLEAR SIGNALING BY ERBB4 | 31 | 5.48e-01 | 6.24e-02 | 6.92e-01 |
| METABOLISM OF STEROID HORMONES | 20 | 6.29e-01 | 6.24e-02 | 7.53e-01 |
| SEMAPHORIN INTERACTIONS | 64 | 3.89e-01 | -6.23e-02 | 5.58e-01 |
| CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA | 59 | 4.13e-01 | -6.17e-02 | 5.78e-01 |
| TRNA PROCESSING IN THE NUCLEUS | 56 | 4.26e-01 | -6.15e-02 | 5.89e-01 |
| METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS | 100 | 2.89e-01 | 6.14e-02 | 4.68e-01 |
| MHC CLASS II ANTIGEN PRESENTATION | 103 | 2.83e-01 | 6.13e-02 | 4.61e-01 |
| CELL CELL COMMUNICATION | 107 | 2.75e-01 | 6.11e-02 | 4.53e-01 |
| SIGNALING BY PDGF | 55 | 4.34e-01 | -6.10e-02 | 5.97e-01 |
| BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION | 26 | 5.91e-01 | -6.09e-02 | 7.24e-01 |
| RET SIGNALING | 37 | 5.22e-01 | 6.09e-02 | 6.72e-01 |
| MAP2K AND MAPK ACTIVATION | 36 | 5.29e-01 | 6.07e-02 | 6.78e-01 |
| CA DEPENDENT EVENTS | 36 | 5.30e-01 | 6.05e-02 | 6.78e-01 |
| SEMA3A PAK DEPENDENT AXON REPULSION | 16 | 6.75e-01 | 6.05e-02 | 7.93e-01 |
| MITOCHONDRIAL BIOGENESIS | 92 | 3.19e-01 | 6.01e-02 | 4.96e-01 |
| ONCOGENE INDUCED SENESCENCE | 32 | 5.56e-01 | -6.01e-02 | 6.99e-01 |
| CELLULAR RESPONSE TO HEAT STRESS | 95 | 3.13e-01 | 5.99e-02 | 4.88e-01 |
| TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES | 45 | 4.95e-01 | -5.88e-02 | 6.49e-01 |
| NICOTINAMIDE SALVAGING | 15 | 6.94e-01 | -5.86e-02 | 8.10e-01 |
| ER TO GOLGI ANTEROGRADE TRANSPORT | 141 | 2.31e-01 | 5.84e-02 | 4.11e-01 |
| POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE | 25 | 6.14e-01 | 5.84e-02 | 7.42e-01 |
| ION CHANNEL TRANSPORT | 138 | 2.39e-01 | -5.82e-02 | 4.17e-01 |
| RHOF GTPASE CYCLE | 40 | 5.29e-01 | 5.75e-02 | 6.78e-01 |
| SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP | 63 | 4.34e-01 | 5.70e-02 | 5.97e-01 |
| FGFR2 ALTERNATIVE SPLICING | 26 | 6.15e-01 | -5.70e-02 | 7.43e-01 |
| CIRCADIAN CLOCK | 68 | 4.16e-01 | 5.70e-02 | 5.82e-01 |
| DISEASES OF MITOTIC CELL CYCLE | 37 | 5.50e-01 | -5.67e-02 | 6.94e-01 |
| CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | 74 | 4.01e-01 | -5.65e-02 | 5.69e-01 |
| COPI MEDIATED ANTEROGRADE TRANSPORT | 90 | 3.56e-01 | 5.63e-02 | 5.29e-01 |
| SIGNALING BY NOTCH | 188 | 1.86e-01 | 5.60e-02 | 3.63e-01 |
| THE PHOTOTRANSDUCTION CASCADE | 20 | 6.65e-01 | 5.60e-02 | 7.84e-01 |
| SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 | 628 | 1.72e-02 | 5.59e-02 | 6.84e-02 |
| SLC MEDIATED TRANSMEMBRANE TRANSPORT | 183 | 1.93e-01 | 5.59e-02 | 3.68e-01 |
| DNA DOUBLE STRAND BREAK REPAIR | 136 | 2.61e-01 | -5.59e-02 | 4.39e-01 |
| NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 | 11 | 7.49e-01 | -5.58e-02 | 8.53e-01 |
| REPRODUCTION | 75 | 4.06e-01 | -5.55e-02 | 5.73e-01 |
| DISEASES OF PROGRAMMED CELL DEATH | 54 | 4.81e-01 | 5.55e-02 | 6.37e-01 |
| REGULATION OF BETA CELL DEVELOPMENT | 24 | 6.43e-01 | -5.47e-02 | 7.64e-01 |
| MITOTIC PROPHASE | 92 | 3.69e-01 | 5.43e-02 | 5.40e-01 |
| DISEASES OF METABOLISM | 198 | 1.89e-01 | 5.42e-02 | 3.66e-01 |
| SIGNALING BY NOTCH1 | 75 | 4.19e-01 | -5.41e-02 | 5.84e-01 |
| RNA POLYMERASE I TRANSCRIPTION | 67 | 4.45e-01 | 5.40e-02 | 6.08e-01 |
| G ALPHA S SIGNALLING EVENTS | 103 | 3.46e-01 | 5.37e-02 | 5.23e-01 |
| EPIGENETIC REGULATION OF GENE EXPRESSION | 103 | 3.47e-01 | -5.37e-02 | 5.23e-01 |
| RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR | 20 | 6.81e-01 | 5.30e-02 | 7.98e-01 |
| PROCESSING OF CAPPED INTRONLESS PRE MRNA | 28 | 6.27e-01 | -5.30e-02 | 7.52e-01 |
| NOD1 2 SIGNALING PATHWAY | 35 | 5.88e-01 | 5.29e-02 | 7.23e-01 |
| INTERFERON ALPHA BETA SIGNALING | 52 | 5.18e-01 | 5.18e-02 | 6.68e-01 |
| CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER | 61 | 4.85e-01 | 5.17e-02 | 6.40e-01 |
| IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | 10 | 7.78e-01 | 5.14e-02 | 8.70e-01 |
| UNWINDING OF DNA | 12 | 7.58e-01 | 5.14e-02 | 8.58e-01 |
| RRNA PROCESSING IN THE MITOCHONDRION | 10 | 7.79e-01 | 5.11e-02 | 8.70e-01 |
| TRAF6 MEDIATED IRF7 ACTIVATION | 15 | 7.32e-01 | -5.10e-02 | 8.39e-01 |
| REDUCTION OF CYTOSOLIC CA LEVELS | 11 | 7.71e-01 | -5.06e-02 | 8.67e-01 |
| PI3K AKT SIGNALING IN CANCER | 88 | 4.13e-01 | 5.06e-02 | 5.78e-01 |
| TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN | 20 | 6.98e-01 | 5.01e-02 | 8.12e-01 |
| BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS | 11 | 7.74e-01 | 5.00e-02 | 8.67e-01 |
| B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION | 47 | 5.53e-01 | 5.00e-02 | 6.97e-01 |
| TRANSMISSION ACROSS CHEMICAL SYNAPSES | 235 | 1.88e-01 | 5.00e-02 | 3.65e-01 |
| ADENYLATE CYCLASE INHIBITORY PATHWAY | 13 | 7.56e-01 | 4.98e-02 | 8.58e-01 |
| MITOTIC G2 G2 M PHASES | 184 | 2.47e-01 | 4.96e-02 | 4.23e-01 |
| CHROMOSOME MAINTENANCE | 103 | 3.86e-01 | 4.94e-02 | 5.56e-01 |
| SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA | 41 | 5.89e-01 | 4.87e-02 | 7.23e-01 |
| TRNA AMINOACYLATION | 42 | 5.85e-01 | 4.87e-02 | 7.21e-01 |
| VLDLR INTERNALISATION AND DEGRADATION | 12 | 7.71e-01 | 4.86e-02 | 8.67e-01 |
| INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS | 35 | 6.19e-01 | -4.85e-02 | 7.47e-01 |
| SUMOYLATION OF UBIQUITINYLATION PROTEINS | 37 | 6.10e-01 | -4.84e-02 | 7.41e-01 |
| SIGNALING BY NOTCH3 | 48 | 5.67e-01 | -4.77e-02 | 7.07e-01 |
| CELL CYCLE | 588 | 5.07e-02 | 4.74e-02 | 1.45e-01 |
| SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | 11 | 7.86e-01 | 4.74e-02 | 8.73e-01 |
| SENSORY PERCEPTION | 140 | 3.34e-01 | 4.73e-02 | 5.11e-01 |
| NICOTINATE METABOLISM | 24 | 6.93e-01 | -4.66e-02 | 8.09e-01 |
| RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN | 37 | 6.25e-01 | -4.65e-02 | 7.51e-01 |
| EPHA MEDIATED GROWTH CONE COLLAPSE | 27 | 6.76e-01 | -4.64e-02 | 7.93e-01 |
| HOMOLOGY DIRECTED REPAIR | 107 | 4.16e-01 | -4.55e-02 | 5.82e-01 |
| ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS | 83 | 4.74e-01 | -4.55e-02 | 6.31e-01 |
| REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION | 87 | 4.64e-01 | -4.54e-02 | 6.22e-01 |
| TELOMERE C STRAND LAGGING STRAND SYNTHESIS | 33 | 6.52e-01 | 4.53e-02 | 7.72e-01 |
| RNA POLYMERASE II TRANSCRIBES SNRNA GENES | 74 | 5.06e-01 | -4.48e-02 | 6.57e-01 |
| P75 NTR RECEPTOR MEDIATED SIGNALLING | 95 | 4.59e-01 | -4.40e-02 | 6.17e-01 |
| INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC | 184 | 3.07e-01 | 4.38e-02 | 4.83e-01 |
| MITOCHONDRIAL TRNA AMINOACYLATION | 21 | 7.29e-01 | -4.37e-02 | 8.37e-01 |
| FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | 117 | 4.21e-01 | -4.31e-02 | 5.85e-01 |
| METABOLISM OF FOLATE AND PTERINES | 15 | 7.74e-01 | 4.29e-02 | 8.67e-01 |
| CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND | 10 | 8.16e-01 | -4.26e-02 | 8.93e-01 |
| CARDIAC CONDUCTION | 108 | 4.47e-01 | -4.24e-02 | 6.08e-01 |
| PLASMA LIPOPROTEIN REMODELING | 15 | 7.77e-01 | -4.23e-02 | 8.69e-01 |
| SUMOYLATION OF TRANSCRIPTION COFACTORS | 42 | 6.36e-01 | -4.22e-02 | 7.58e-01 |
| NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 65 | 5.57e-01 | 4.21e-02 | 6.99e-01 |
| SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS | 11 | 8.10e-01 | 4.19e-02 | 8.90e-01 |
| GLYCOLYSIS | 66 | 5.58e-01 | 4.18e-02 | 6.99e-01 |
| PHOSPHORYLATION OF THE APC C | 17 | 7.68e-01 | 4.13e-02 | 8.65e-01 |
| TERMINATION OF TRANSLESION DNA SYNTHESIS | 30 | 6.97e-01 | 4.11e-02 | 8.12e-01 |
| AGGREPHAGY | 35 | 6.75e-01 | 4.10e-02 | 7.93e-01 |
| CD28 DEPENDENT PI3K AKT SIGNALING | 19 | 7.58e-01 | -4.08e-02 | 8.58e-01 |
| ATTENUATION PHASE | 24 | 7.31e-01 | 4.05e-02 | 8.39e-01 |
| ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | 73 | 5.53e-01 | -4.02e-02 | 6.97e-01 |
| PYRIMIDINE CATABOLISM | 10 | 8.26e-01 | -4.02e-02 | 9.01e-01 |
| SLC TRANSPORTER DISORDERS | 69 | 5.65e-01 | 4.01e-02 | 7.05e-01 |
| SIGNALING BY ACTIVIN | 12 | 8.10e-01 | 4.01e-02 | 8.90e-01 |
| NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 48 | 6.33e-01 | -3.99e-02 | 7.55e-01 |
| LAMININ INTERACTIONS | 27 | 7.20e-01 | -3.98e-02 | 8.30e-01 |
| NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 26 | 7.26e-01 | -3.97e-02 | 8.35e-01 |
| PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE | 19 | 7.67e-01 | -3.93e-02 | 8.64e-01 |
| REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA | 13 | 8.07e-01 | -3.91e-02 | 8.90e-01 |
| RNA POLYMERASE I TRANSCRIPTION TERMINATION | 31 | 7.07e-01 | -3.91e-02 | 8.19e-01 |
| DISEASES OF GLYCOSYLATION | 124 | 4.54e-01 | -3.90e-02 | 6.14e-01 |
| WNT5A DEPENDENT INTERNALIZATION OF FZD4 | 15 | 7.94e-01 | -3.90e-02 | 8.81e-01 |
| PHOSPHOLIPID METABOLISM | 185 | 3.64e-01 | 3.88e-02 | 5.35e-01 |
| NEPHRIN FAMILY INTERACTIONS | 22 | 7.55e-01 | 3.84e-02 | 8.58e-01 |
| DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS | 17 | 7.85e-01 | 3.82e-02 | 8.73e-01 |
| INHIBITION OF DNA RECOMBINATION AT TELOMERE | 35 | 6.98e-01 | 3.78e-02 | 8.12e-01 |
| RHOC GTPASE CYCLE | 73 | 5.83e-01 | -3.72e-02 | 7.19e-01 |
| INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | 34 | 7.09e-01 | -3.70e-02 | 8.20e-01 |
| MEIOSIS | 63 | 6.14e-01 | -3.68e-02 | 7.42e-01 |
| MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES | 31 | 7.25e-01 | 3.65e-02 | 8.34e-01 |
| TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | 79 | 5.75e-01 | -3.65e-02 | 7.13e-01 |
| RHOB GTPASE CYCLE | 67 | 6.06e-01 | -3.65e-02 | 7.38e-01 |
| MEIOTIC SYNAPSIS | 39 | 6.94e-01 | -3.64e-02 | 8.10e-01 |
| RNA POLYMERASE I TRANSCRIPTION INITIATION | 47 | 6.67e-01 | -3.63e-02 | 7.86e-01 |
| NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 23 | 7.67e-01 | 3.58e-02 | 8.64e-01 |
| MRNA CAPPING | 29 | 7.42e-01 | 3.53e-02 | 8.48e-01 |
| RHO GTPASE CYCLE | 427 | 2.18e-01 | 3.49e-02 | 3.94e-01 |
| SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS | 73 | 6.10e-01 | 3.46e-02 | 7.41e-01 |
| SUMOYLATION OF RNA BINDING PROTEINS | 45 | 6.89e-01 | -3.46e-02 | 8.05e-01 |
| NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION | 175 | 4.33e-01 | 3.44e-02 | 5.97e-01 |
| REGULATION OF TP53 ACTIVITY | 148 | 4.77e-01 | -3.39e-02 | 6.34e-01 |
| TRANSCRIPTIONAL REGULATION BY SMALL RNAS | 61 | 6.52e-01 | -3.34e-02 | 7.72e-01 |
| TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | 82 | 6.02e-01 | -3.33e-02 | 7.35e-01 |
| CHEMOKINE RECEPTORS BIND CHEMOKINES | 15 | 8.27e-01 | 3.26e-02 | 9.01e-01 |
| ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION | 32 | 7.51e-01 | 3.24e-02 | 8.54e-01 |
| INTERLEUKIN 17 SIGNALING | 66 | 6.55e-01 | 3.18e-02 | 7.74e-01 |
| EXTRACELLULAR MATRIX ORGANIZATION | 239 | 4.12e-01 | -3.09e-02 | 5.78e-01 |
| DNA DOUBLE STRAND BREAK RESPONSE | 52 | 7.03e-01 | 3.05e-02 | 8.17e-01 |
| HEPARAN SULFATE HEPARIN HS GAG METABOLISM | 51 | 7.09e-01 | 3.02e-02 | 8.20e-01 |
| ACYL CHAIN REMODELLING OF PC | 17 | 8.33e-01 | 2.96e-02 | 9.04e-01 |
| GOLGI TO ER RETROGRADE TRANSPORT | 118 | 5.87e-01 | 2.90e-02 | 7.22e-01 |
| TELOMERE C STRAND SYNTHESIS INITIATION | 13 | 8.58e-01 | -2.87e-02 | 9.23e-01 |
| TRANSCRIPTIONAL REGULATION BY RUNX1 | 176 | 5.13e-01 | 2.86e-02 | 6.65e-01 |
| NUCLEOTIDE SALVAGE | 21 | 8.22e-01 | -2.84e-02 | 8.98e-01 |
| NONHOMOLOGOUS END JOINING NHEJ | 43 | 7.48e-01 | -2.83e-02 | 8.53e-01 |
| RHOU GTPASE CYCLE | 33 | 7.81e-01 | -2.80e-02 | 8.71e-01 |
| ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS | 19 | 8.35e-01 | 2.76e-02 | 9.04e-01 |
| METABOLISM OF FAT SOLUBLE VITAMINS | 31 | 7.92e-01 | 2.74e-02 | 8.79e-01 |
| SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | 20 | 8.34e-01 | -2.70e-02 | 9.04e-01 |
| POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 62 | 7.14e-01 | 2.70e-02 | 8.24e-01 |
| RAC1 GTPASE CYCLE | 177 | 5.39e-01 | 2.68e-02 | 6.88e-01 |
| DNA METHYLATION | 20 | 8.36e-01 | -2.68e-02 | 9.04e-01 |
| OTHER INTERLEUKIN SIGNALING | 20 | 8.41e-01 | 2.60e-02 | 9.07e-01 |
| ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | 32 | 8.00e-01 | -2.59e-02 | 8.85e-01 |
| TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA | 16 | 8.63e-01 | -2.49e-02 | 9.27e-01 |
| MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | 15 | 8.69e-01 | -2.46e-02 | 9.27e-01 |
| SEMA4D IN SEMAPHORIN SIGNALING | 24 | 8.36e-01 | 2.45e-02 | 9.04e-01 |
| ONCOGENIC MAPK SIGNALING | 77 | 7.11e-01 | 2.44e-02 | 8.22e-01 |
| SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL | 26 | 8.32e-01 | -2.41e-02 | 9.04e-01 |
| INTEGRIN CELL SURFACE INTERACTIONS | 68 | 7.35e-01 | -2.37e-02 | 8.41e-01 |
| SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | 16 | 8.70e-01 | 2.37e-02 | 9.27e-01 |
| CELL CELL JUNCTION ORGANIZATION | 50 | 7.73e-01 | 2.36e-02 | 8.67e-01 |
| PHASE 4 RESTING MEMBRANE POTENTIAL | 14 | 8.79e-01 | 2.35e-02 | 9.33e-01 |
| INTERLEUKIN 6 SIGNALING | 10 | 8.98e-01 | -2.35e-02 | 9.40e-01 |
| VISUAL PHOTOTRANSDUCTION | 58 | 7.57e-01 | 2.35e-02 | 8.58e-01 |
| TRANSCRIPTIONAL REGULATION BY E2F6 | 34 | 8.14e-01 | -2.33e-02 | 8.92e-01 |
| ACYL CHAIN REMODELLING OF PS | 14 | 8.81e-01 | -2.32e-02 | 9.33e-01 |
| ERBB2 REGULATES CELL MOTILITY | 14 | 8.81e-01 | 2.31e-02 | 9.33e-01 |
| POTASSIUM CHANNELS | 90 | 7.06e-01 | -2.30e-02 | 8.19e-01 |
| G1 S SPECIFIC TRANSCRIPTION | 26 | 8.40e-01 | 2.29e-02 | 9.07e-01 |
| EXTENSION OF TELOMERES | 50 | 7.82e-01 | -2.26e-02 | 8.72e-01 |
| PREGNENOLONE BIOSYNTHESIS | 12 | 8.93e-01 | 2.23e-02 | 9.39e-01 |
| HSF1 DEPENDENT TRANSACTIVATION | 34 | 8.22e-01 | 2.23e-02 | 8.98e-01 |
| ACTIVATION OF GENE EXPRESSION BY SREBF SREBP | 43 | 8.03e-01 | 2.20e-02 | 8.88e-01 |
| BASE EXCISION REPAIR | 56 | 7.77e-01 | -2.19e-02 | 8.69e-01 |
| O LINKED GLYCOSYLATION OF MUCINS | 40 | 8.11e-01 | 2.19e-02 | 8.90e-01 |
| GROWTH HORMONE RECEPTOR SIGNALING | 20 | 8.69e-01 | -2.14e-02 | 9.27e-01 |
| TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY | 13 | 8.94e-01 | 2.13e-02 | 9.39e-01 |
| MITOTIC PROMETAPHASE | 175 | 6.36e-01 | -2.08e-02 | 7.58e-01 |
| SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | 52 | 7.97e-01 | -2.06e-02 | 8.83e-01 |
| RESOLUTION OF ABASIC SITES AP SITES | 37 | 8.31e-01 | -2.03e-02 | 9.04e-01 |
| AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS | 10 | 9.12e-01 | 2.02e-02 | 9.49e-01 |
| SENSORY PROCESSING OF SOUND | 61 | 7.85e-01 | 2.02e-02 | 8.73e-01 |
| RHOD GTPASE CYCLE | 50 | 8.09e-01 | 1.97e-02 | 8.90e-01 |
| MEIOTIC RECOMBINATION | 38 | 8.33e-01 | 1.97e-02 | 9.04e-01 |
| TELOMERE MAINTENANCE | 79 | 7.62e-01 | 1.97e-02 | 8.61e-01 |
| ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | 23 | 8.71e-01 | -1.96e-02 | 9.27e-01 |
| HCMV INFECTION | 102 | 7.35e-01 | -1.94e-02 | 8.41e-01 |
| P38MAPK EVENTS | 13 | 9.08e-01 | -1.86e-02 | 9.47e-01 |
| NON INTEGRIN MEMBRANE ECM INTERACTIONS | 55 | 8.12e-01 | 1.86e-02 | 8.90e-01 |
| TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY | 29 | 8.68e-01 | 1.78e-02 | 9.27e-01 |
| INTERLEUKIN 15 SIGNALING | 12 | 9.17e-01 | -1.75e-02 | 9.52e-01 |
| G ALPHA 12 13 SIGNALLING EVENTS | 75 | 7.98e-01 | 1.71e-02 | 8.83e-01 |
| RMTS METHYLATE HISTONE ARGININES | 42 | 8.49e-01 | -1.70e-02 | 9.14e-01 |
| CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER | 26 | 8.81e-01 | 1.70e-02 | 9.33e-01 |
| GRB2 EVENTS IN ERBB2 SIGNALING | 15 | 9.14e-01 | 1.62e-02 | 9.50e-01 |
| POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION | 26 | 8.87e-01 | -1.62e-02 | 9.36e-01 |
| G0 AND EARLY G1 | 24 | 8.92e-01 | 1.60e-02 | 9.39e-01 |
| EPH EPHRIN MEDIATED REPULSION OF CELLS | 49 | 8.47e-01 | 1.59e-02 | 9.13e-01 |
| RHOA GTPASE CYCLE | 143 | 7.44e-01 | 1.58e-02 | 8.49e-01 |
| HDR THROUGH SINGLE STRAND ANNEALING SSA | 36 | 8.70e-01 | -1.58e-02 | 9.27e-01 |
| SNRNP ASSEMBLY | 51 | 8.47e-01 | -1.57e-02 | 9.13e-01 |
| RAF INDEPENDENT MAPK1 3 ACTIVATION | 21 | 9.02e-01 | 1.55e-02 | 9.43e-01 |
| SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL | 13 | 9.24e-01 | -1.54e-02 | 9.56e-01 |
| COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 85 | 8.08e-01 | -1.53e-02 | 8.90e-01 |
| BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS | 30 | 8.86e-01 | 1.52e-02 | 9.36e-01 |
| SUMOYLATION | 162 | 7.43e-01 | -1.49e-02 | 8.49e-01 |
| APOPTOSIS INDUCED DNA FRAGMENTATION | 10 | 9.36e-01 | 1.47e-02 | 9.60e-01 |
| NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 20 | 9.10e-01 | -1.46e-02 | 9.48e-01 |
| INTRA GOLGI TRAFFIC | 43 | 8.70e-01 | 1.44e-02 | 9.27e-01 |
| IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS | 12 | 9.31e-01 | 1.43e-02 | 9.60e-01 |
| MUSCLE CONTRACTION | 162 | 7.61e-01 | -1.39e-02 | 8.60e-01 |
| CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | 12 | 9.35e-01 | -1.37e-02 | 9.60e-01 |
| FORMATION OF THE EARLY ELONGATION COMPLEX | 33 | 8.95e-01 | 1.32e-02 | 9.39e-01 |
| SIGNALING BY BRAF AND RAF FUSIONS | 60 | 8.65e-01 | -1.27e-02 | 9.27e-01 |
| TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE | 37 | 8.95e-01 | 1.25e-02 | 9.39e-01 |
| SUMOYLATION OF DNA REPLICATION PROTEINS | 42 | 8.89e-01 | -1.24e-02 | 9.37e-01 |
| RNA POLYMERASE II TRANSCRIPTION TERMINATION | 65 | 8.65e-01 | 1.22e-02 | 9.27e-01 |
| HCMV LATE EVENTS | 64 | 8.68e-01 | 1.20e-02 | 9.27e-01 |
| DEPOLYMERISATION OF THE NUCLEAR LAMINA | 12 | 9.42e-01 | 1.20e-02 | 9.63e-01 |
| SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS | 18 | 9.30e-01 | -1.19e-02 | 9.60e-01 |
| ACTIVATION OF MATRIX METALLOPROTEINASES | 14 | 9.39e-01 | 1.18e-02 | 9.61e-01 |
| DEATH RECEPTOR SIGNALLING | 134 | 8.17e-01 | -1.16e-02 | 8.93e-01 |
| TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES | 35 | 9.06e-01 | 1.15e-02 | 9.47e-01 |
| FORMATION OF RNA POL II ELONGATION COMPLEX | 57 | 8.86e-01 | -1.09e-02 | 9.36e-01 |
| FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES | 15 | 9.42e-01 | -1.08e-02 | 9.63e-01 |
| INTERLEUKIN 6 FAMILY SIGNALING | 18 | 9.37e-01 | -1.07e-02 | 9.60e-01 |
| HIV ELONGATION ARREST AND RECOVERY | 32 | 9.17e-01 | 1.07e-02 | 9.52e-01 |
| G2 M DNA DAMAGE CHECKPOINT | 65 | 8.82e-01 | 1.06e-02 | 9.33e-01 |
| SIGNALING BY SCF KIT | 41 | 9.08e-01 | 1.05e-02 | 9.47e-01 |
| PROCESSING OF DNA DOUBLE STRAND BREAK ENDS | 71 | 8.80e-01 | 1.04e-02 | 9.33e-01 |
| PRC2 METHYLATES HISTONES AND DNA | 29 | 9.29e-01 | -9.50e-03 | 9.60e-01 |
| DAG AND IP3 SIGNALING | 40 | 9.18e-01 | -9.45e-03 | 9.52e-01 |
| ACTIVATION OF BH3 ONLY PROTEINS | 28 | 9.34e-01 | -9.02e-03 | 9.60e-01 |
| HYALURONAN METABOLISM | 15 | 9.52e-01 | 9.00e-03 | 9.70e-01 |
| PD 1 SIGNALING | 10 | 9.62e-01 | -8.72e-03 | 9.76e-01 |
| ADHERENS JUNCTIONS INTERACTIONS | 30 | 9.36e-01 | -8.45e-03 | 9.60e-01 |
| INTERFERON GAMMA SIGNALING | 73 | 9.01e-01 | 8.43e-03 | 9.43e-01 |
| DNA DAMAGE BYPASS | 46 | 9.23e-01 | 8.20e-03 | 9.56e-01 |
| ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | 34 | 9.36e-01 | 7.98e-03 | 9.60e-01 |
| ACETYLCHOLINE REGULATES INSULIN SECRETION | 10 | 9.65e-01 | -7.95e-03 | 9.79e-01 |
| FLT3 SIGNALING | 36 | 9.36e-01 | 7.68e-03 | 9.60e-01 |
| RIP MEDIATED NFKB ACTIVATION VIA ZBP1 | 15 | 9.60e-01 | -7.51e-03 | 9.76e-01 |
| RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION | 23 | 9.58e-01 | -6.32e-03 | 9.75e-01 |
| BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA | 16 | 9.70e-01 | 5.49e-03 | 9.82e-01 |
| DEADENYLATION OF MRNA | 25 | 9.62e-01 | -5.49e-03 | 9.76e-01 |
| TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | 77 | 9.34e-01 | 5.45e-03 | 9.60e-01 |
| REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF | 56 | 9.45e-01 | -5.33e-03 | 9.65e-01 |
| ION HOMEOSTASIS | 48 | 9.53e-01 | 4.93e-03 | 9.70e-01 |
| NEURONAL SYSTEM | 363 | 8.75e-01 | -4.81e-03 | 9.31e-01 |
| L1CAM INTERACTIONS | 109 | 9.32e-01 | 4.74e-03 | 9.60e-01 |
| RNA POLYMERASE II TRANSCRIPTION | 1083 | 8.07e-01 | 4.44e-03 | 8.90e-01 |
| TRANSCRIPTIONAL REGULATION BY TP53 | 338 | 8.91e-01 | 4.35e-03 | 9.38e-01 |
| DEFECTIVE EXT2 CAUSES EXOSTOSES 2 | 14 | 9.78e-01 | 4.35e-03 | 9.86e-01 |
| DEREGULATED CDK5 TRIGGERS MULTIPLE NEURODEGENERATIVE PATHWAYS IN ALZHEIMER S DISEASE MODELS | 19 | 9.75e-01 | -4.11e-03 | 9.86e-01 |
| INTERLEUKIN 20 FAMILY SIGNALING | 14 | 9.83e-01 | 3.20e-03 | 9.88e-01 |
| GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | 30 | 9.76e-01 | 3.13e-03 | 9.86e-01 |
| INTERFERON SIGNALING | 160 | 9.46e-01 | -3.09e-03 | 9.65e-01 |
| ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK | 28 | 9.79e-01 | 2.83e-03 | 9.86e-01 |
| SHC1 EVENTS IN ERBB2 SIGNALING | 21 | 9.83e-01 | -2.66e-03 | 9.88e-01 |
| MET PROMOTES CELL MOTILITY | 39 | 9.78e-01 | 2.57e-03 | 9.86e-01 |
| VXPX CARGO TARGETING TO CILIUM | 19 | 9.86e-01 | -2.37e-03 | 9.89e-01 |
| HIV TRANSCRIPTION ELONGATION | 42 | 9.80e-01 | 2.19e-03 | 9.86e-01 |
| PI METABOLISM | 79 | 9.78e-01 | 1.78e-03 | 9.86e-01 |
| ESTROGEN DEPENDENT GENE EXPRESSION | 100 | 9.75e-01 | -1.78e-03 | 9.86e-01 |
| PI3K EVENTS IN ERBB2 SIGNALING | 15 | 9.92e-01 | 1.52e-03 | 9.94e-01 |
| PIWI INTERACTING RNA PIRNA BIOGENESIS | 20 | 9.92e-01 | 1.36e-03 | 9.94e-01 |
| MISMATCH REPAIR | 14 | 9.94e-01 | -1.07e-03 | 9.95e-01 |
| FLT3 SIGNALING IN DISEASE | 27 | 1.00e+00 | -1.34e-05 | 1.00e+00 |
Detailed Gene set reports
TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR
| set | TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR |
| setSize | 11 |
| pANOVA | 0.000176 |
| s.dist | 0.653 |
| p.adjustANOVA | 0.00165 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Ctss | 7952 |
| Lgmn | 7926 |
| Ctsb | 7845 |
| Tlr7 | 7104 |
| Hsp90b1 | 6320 |
| Unc93b1 | 5766 |
| Ctsl | 5480 |
| Tlr3 | 4655 |
| Ctsk | 4395 |
| Cnpy3 | 1652 |
| Tlr9 | -1435 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Ctss | 7952 |
| Lgmn | 7926 |
| Ctsb | 7845 |
| Tlr7 | 7104 |
| Hsp90b1 | 6320 |
| Unc93b1 | 5766 |
| Ctsl | 5480 |
| Tlr3 | 4655 |
| Ctsk | 4395 |
| Cnpy3 | 1652 |
| Tlr9 | -1435 |
NUCLEOTIDE LIKE PURINERGIC RECEPTORS
| set | NUCLEOTIDE LIKE PURINERGIC RECEPTORS |
| setSize | 13 |
| pANOVA | 0.000532 |
| s.dist | 0.555 |
| p.adjustANOVA | 0.00434 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| P2ry12 | 7415 |
| P2ry1 | 7379 |
| Adora3 | 7107 |
| P2ry14 | 7093 |
| P2ry13 | 5910 |
| Gpr17 | 5851 |
| Adora2b | 5034 |
| Adora2a | 4710 |
| P2ry6 | 3721 |
| Lpar4 | 2293 |
| Adora1 | 932 |
| Lpar6 | 570 |
| P2ry2 | -495 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| P2ry12 | 7415 |
| P2ry1 | 7379 |
| Adora3 | 7107 |
| P2ry14 | 7093 |
| P2ry13 | 5910 |
| Gpr17 | 5851 |
| Adora2b | 5034 |
| Adora2a | 4710 |
| P2ry6 | 3721 |
| Lpar4 | 2293 |
| Adora1 | 932 |
| Lpar6 | 570 |
| P2ry2 | -495 |
ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12
| set | ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 |
| setSize | 19 |
| pANOVA | 4.05e-05 |
| s.dist | 0.544 |
| p.adjustANOVA | 0.000513 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Gng12 | 7807 |
| P2ry12 | 7415 |
| Gng10 | 7126 |
| Gng5 | 7048 |
| Gnai3 | 7035 |
| Gnb5 | 6693 |
| Gng11 | 6629 |
| Gng7 | 5131 |
| Gnai1 | 5066 |
| Gng3 | 4235 |
| Gnai2 | 4104 |
| Gngt2 | 2843 |
| Gnb4 | 2643 |
| Gng8 | 2078 |
| Gng4 | 2020 |
| Gng2 | 1559 |
| Gnb2 | 1365 |
| Gng13 | 922 |
| Gnb1 | 595 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Gng12 | 7807 |
| P2ry12 | 7415 |
| Gng10 | 7126 |
| Gng5 | 7048 |
| Gnai3 | 7035 |
| Gnb5 | 6693 |
| Gng11 | 6629 |
| Gng7 | 5131 |
| Gnai1 | 5066 |
| Gng3 | 4235 |
| Gnai2 | 4104 |
| Gngt2 | 2843 |
| Gnb4 | 2643 |
| Gng8 | 2078 |
| Gng4 | 2020 |
| Gng2 | 1559 |
| Gnb2 | 1365 |
| Gng13 | 922 |
| Gnb1 | 595 |
ASPARTATE AND ASPARAGINE METABOLISM
| set | ASPARTATE AND ASPARAGINE METABOLISM |
| setSize | 10 |
| pANOVA | 0.00302 |
| s.dist | 0.542 |
| p.adjustANOVA | 0.0172 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Asns | 7505 |
| Slc25a13 | 7185 |
| Folh1 | 6672 |
| Got1 | 6571 |
| Got2 | 5981 |
| Naalad2 | 5320 |
| Aspa | 4959 |
| Slc25a12 | 4531 |
| Nat8l | 103 |
| Aspg | -5666 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Asns | 7505 |
| Slc25a13 | 7185 |
| Folh1 | 6672 |
| Got1 | 6571 |
| Got2 | 5981 |
| Naalad2 | 5320 |
| Aspa | 4959 |
| Slc25a12 | 4531 |
| Nat8l | 103 |
| Aspg | -5666 |
COMPLEX I BIOGENESIS
| set | COMPLEX I BIOGENESIS |
| setSize | 56 |
| pANOVA | 4.15e-12 |
| s.dist | 0.535 |
| p.adjustANOVA | 2.85e-10 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Ndufb5 | 7945 |
| Ndufv2 | 7898 |
| Ndufc1 | 7880 |
| Ndufaf4 | 7876 |
| mt-Nd4 | 7792 |
| mt-Nd3 | 7697 |
| mt-Nd6 | 7693 |
| mt-Nd1 | 7591 |
| Ndufa12 | 7567 |
| Ndufs4 | 7518 |
| Ndufs2 | 7517 |
| mt-Nd5 | 7515 |
| Ndufa10 | 7482 |
| mt-Nd2 | 7442 |
| Timmdc1 | 7363 |
| Ndufaf1 | 7142 |
| Ndufa5 | 7113 |
| Ndufb9 | 6753 |
| Ndufaf6 | 6598 |
| Ndufb4 | 6560 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Ndufb5 | 7945 |
| Ndufv2 | 7898 |
| Ndufc1 | 7880 |
| Ndufaf4 | 7876 |
| mt-Nd4 | 7792 |
| mt-Nd3 | 7697 |
| mt-Nd6 | 7693 |
| mt-Nd1 | 7591 |
| Ndufa12 | 7567 |
| Ndufs4 | 7518 |
| Ndufs2 | 7517 |
| mt-Nd5 | 7515 |
| Ndufa10 | 7482 |
| mt-Nd2 | 7442 |
| Timmdc1 | 7363 |
| Ndufaf1 | 7142 |
| Ndufa5 | 7113 |
| Ndufb9 | 6753 |
| Ndufaf6 | 6598 |
| Ndufb4 | 6560 |
| Ndufb11 | 6480 |
| Ndufs1 | 6382 |
| Ndufaf2 | 6189 |
| Ndufb8 | 6188 |
| Ndufs3 | 6002 |
| Ndufa13 | 5847 |
| Ndufaf5 | 5686 |
| Ndufab1 | 5623 |
| Ndufc2 | 4817 |
| Ndufa6 | 4773 |
| Ndufs5 | 4714 |
| Ndufa7 | 4536 |
| Ndufb6 | 4186 |
| Ndufs6 | 3840 |
| Ndufv1 | 3475 |
| Ndufb1 | 3426 |
| Tmem126b | 3235 |
| Ndufa1 | 2823 |
| Ndufb3 | 2500 |
| Ecsit | 2348 |
| Ndufs7 | 2106 |
| Acad9 | 1991 |
| Ndufa8 | 1700 |
| Ndufb7 | 1370 |
| Ndufb2 | 1235 |
| Ndufs8 | 350 |
| Ndufb10 | 315 |
| Ndufv3 | 202 |
| Nubpl | 24 |
| Ndufa3 | -187 |
| Ndufa11 | -921 |
| Ndufaf3 | -1144 |
| Ndufa9 | -1155 |
| Ndufaf7 | -1201 |
| Ndufa2 | -1362 |
| Tmem186 | -7246 |
SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS
| set | SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS |
| setSize | 20 |
| pANOVA | 3.49e-05 |
| s.dist | 0.535 |
| p.adjustANOVA | 0.000458 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Elovl1 | 8118 |
| Hsd17b12 | 7867 |
| Elovl5 | 7775 |
| Hacd3 | 7770 |
| Acsbg1 | 7557 |
| Acsl3 | 7542 |
| Hacd1 | 7419 |
| Hacd2 | 7203 |
| Elovl4 | 6856 |
| Acsl4 | 5773 |
| Elovl2 | 5589 |
| Tecr | 4332 |
| Acsl1 | 4283 |
| Elovl7 | 3643 |
| Acsl6 | 3626 |
| Elovl6 | 1439 |
| Hacd4 | -253 |
| Acsl5 | -955 |
| Slc27a3 | -5089 |
| Acsf3 | -5413 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Elovl1 | 8118 |
| Hsd17b12 | 7867 |
| Elovl5 | 7775 |
| Hacd3 | 7770 |
| Acsbg1 | 7557 |
| Acsl3 | 7542 |
| Hacd1 | 7419 |
| Hacd2 | 7203 |
| Elovl4 | 6856 |
| Acsl4 | 5773 |
| Elovl2 | 5589 |
| Tecr | 4332 |
| Acsl1 | 4283 |
| Elovl7 | 3643 |
| Acsl6 | 3626 |
| Elovl6 | 1439 |
| Hacd4 | -253 |
| Acsl5 | -955 |
| Slc27a3 | -5089 |
| Acsf3 | -5413 |
TRIGLYCERIDE CATABOLISM
| set | TRIGLYCERIDE CATABOLISM |
| setSize | 14 |
| pANOVA | 0.000666 |
| s.dist | 0.525 |
| p.adjustANOVA | 0.00527 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Cav1 | 8036 |
| Plin3 | 7872 |
| Ppp1cc | 7076 |
| Abhd5 | 7018 |
| Ppp1cb | 6638 |
| Prkacb | 6523 |
| Fabp5 | 6250 |
| Lipe | 4720 |
| Ppp1ca | 4210 |
| Gpd2 | 3446 |
| Fabp3 | 1587 |
| Mgll | 872 |
| Prkaca | 1 |
| Fabp7 | -5741 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Cav1 | 8036 |
| Plin3 | 7872 |
| Ppp1cc | 7076 |
| Abhd5 | 7018 |
| Ppp1cb | 6638 |
| Prkacb | 6523 |
| Fabp5 | 6250 |
| Lipe | 4720 |
| Ppp1ca | 4210 |
| Gpd2 | 3446 |
| Fabp3 | 1587 |
| Mgll | 872 |
| Prkaca | 1 |
| Fabp7 | -5741 |
PINK1 PRKN MEDIATED MITOPHAGY
| set | PINK1 PRKN MEDIATED MITOPHAGY |
| setSize | 22 |
| pANOVA | 2.43e-05 |
| s.dist | 0.52 |
| p.adjustANOVA | 0.000333 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Tomm20 | 7699 |
| Tomm6 | 6889 |
| Atg5 | 6464 |
| Rps27a | 6289 |
| Map1lc3b | 5971 |
| Vdac1 | 5872 |
| Tomm22 | 5807 |
| Pink1 | 5613 |
| Tomm70a | 5591 |
| Sqstm1 | 5435 |
| Atg12 | 4936 |
| Uba52 | 4681 |
| Ubb | 4464 |
| Map1lc3a | 4293 |
| Mterf3 | 4098 |
| Prkn | 4078 |
| Tomm7 | 2401 |
| Tomm5 | 1994 |
| Tomm40 | 1049 |
| Mfn2 | -565 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Tomm20 | 7699 |
| Tomm6 | 6889 |
| Atg5 | 6464 |
| Rps27a | 6289 |
| Map1lc3b | 5971 |
| Vdac1 | 5872 |
| Tomm22 | 5807 |
| Pink1 | 5613 |
| Tomm70a | 5591 |
| Sqstm1 | 5435 |
| Atg12 | 4936 |
| Uba52 | 4681 |
| Ubb | 4464 |
| Map1lc3a | 4293 |
| Mterf3 | 4098 |
| Prkn | 4078 |
| Tomm7 | 2401 |
| Tomm5 | 1994 |
| Tomm40 | 1049 |
| Mfn2 | -565 |
| Ubc | -674 |
| Mfn1 | -1475 |
FRS MEDIATED FGFR4 SIGNALING
| set | FRS MEDIATED FGFR4 SIGNALING |
| setSize | 12 |
| pANOVA | 0.00191 |
| s.dist | 0.518 |
| p.adjustANOVA | 0.0121 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Fgf1 | 7468 |
| Hras | 6145 |
| Fgf2 | 5929 |
| Kras | 5615 |
| Frs2 | 4437 |
| Fgf9 | 4378 |
| Nras | 3870 |
| Fgf18 | 3659 |
| Ptpn11 | 3578 |
| Frs3 | 2470 |
| Grb2 | 1153 |
| Sos1 | 678 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Fgf1 | 7468 |
| Hras | 6145 |
| Fgf2 | 5929 |
| Kras | 5615 |
| Frs2 | 4437 |
| Fgf9 | 4378 |
| Nras | 3870 |
| Fgf18 | 3659 |
| Ptpn11 | 3578 |
| Frs3 | 2470 |
| Grb2 | 1153 |
| Sos1 | 678 |
SHC MEDIATED CASCADE FGFR4
| set | SHC MEDIATED CASCADE FGFR4 |
| setSize | 10 |
| pANOVA | 0.00472 |
| s.dist | 0.516 |
| p.adjustANOVA | 0.0243 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Fgf1 | 7468 |
| Hras | 6145 |
| Fgf2 | 5929 |
| Kras | 5615 |
| Fgf9 | 4378 |
| Nras | 3870 |
| Fgf18 | 3659 |
| Shc1 | 2133 |
| Grb2 | 1153 |
| Sos1 | 678 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Fgf1 | 7468 |
| Hras | 6145 |
| Fgf2 | 5929 |
| Kras | 5615 |
| Fgf9 | 4378 |
| Nras | 3870 |
| Fgf18 | 3659 |
| Shc1 | 2133 |
| Grb2 | 1153 |
| Sos1 | 678 |
EUKARYOTIC TRANSLATION ELONGATION
| set | EUKARYOTIC TRANSLATION ELONGATION |
| setSize | 87 |
| pANOVA | 1.03e-16 |
| s.dist | 0.515 |
| p.adjustANOVA | 1.1e-14 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Rps25 | 7859 |
| Rps9 | 7628 |
| Rpl23a | 7570 |
| Rpl24 | 7541 |
| Rps27l | 7478 |
| Eef1g | 7476 |
| Rps8 | 7353 |
| Rps3a1 | 7092 |
| Eef1a1 | 7065 |
| Rpl22l1 | 6947 |
| Rps23 | 6816 |
| Eef1a2 | 6783 |
| Rpl6 | 6754 |
| Rps4x | 6721 |
| Rpl23 | 6524 |
| Rps24 | 6393 |
| Rps7 | 6303 |
| Rps27a | 6289 |
| Rpl37a | 6191 |
| Rpl4 | 6149 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Rps25 | 7859 |
| Rps9 | 7628 |
| Rpl23a | 7570 |
| Rpl24 | 7541 |
| Rps27l | 7478 |
| Eef1g | 7476 |
| Rps8 | 7353 |
| Rps3a1 | 7092 |
| Eef1a1 | 7065 |
| Rpl22l1 | 6947 |
| Rps23 | 6816 |
| Eef1a2 | 6783 |
| Rpl6 | 6754 |
| Rps4x | 6721 |
| Rpl23 | 6524 |
| Rps24 | 6393 |
| Rps7 | 6303 |
| Rps27a | 6289 |
| Rpl37a | 6191 |
| Rpl4 | 6149 |
| Rpl13a | 6125 |
| Rpl5 | 6040 |
| Rpl3 | 5937 |
| Rplp0 | 5892 |
| Rpl22 | 5878 |
| Rps29 | 5799 |
| Fau | 5748 |
| Rpl31 | 5694 |
| Rpl17 | 5605 |
| Rpl14 | 5536 |
| Rps18 | 5497 |
| Rpl35a | 5485 |
| Eef1b2 | 5434 |
| Rps20 | 5423 |
| Rpl18a | 5353 |
| Rps19 | 5332 |
| Rpl11 | 5303 |
| Eef2 | 5251 |
| Rps26 | 5236 |
| Rpl27 | 5212 |
| Rpl30 | 5199 |
| Rpl9 | 5143 |
| Rpl7 | 5021 |
| Rps5 | 4951 |
| Rpl39 | 4874 |
| Uba52 | 4681 |
| Rpl32 | 4628 |
| Rpl35 | 4266 |
| Rpl36a | 4039 |
| Rpl38 | 4000 |
| Rps28 | 3896 |
| Rpl29 | 3664 |
| Rpl26 | 3635 |
| Rpl19 | 3569 |
| Rps11 | 3520 |
| Rpl34 | 3516 |
| Eef1d | 3441 |
| Rpl13 | 3237 |
| Rps21 | 3189 |
| Rpsa | 3114 |
| Rpl15 | 3021 |
| Rpl37 | 2954 |
| Rpl27a | 2792 |
| Rps17 | 2735 |
| Rpl21 | 2679 |
| Rpl8 | 2676 |
| Rpl7a | 2289 |
| Rps27 | 2205 |
| Rps13 | 2151 |
| Rps6 | 2047 |
| Rps16 | 1905 |
| Rpl36al | 1812 |
| Rps2 | 1413 |
| Rps3 | 1378 |
| Rps10 | 1099 |
| Rpl28 | 834 |
| Rplp2 | 776 |
| Rpl10a | 729 |
| Rps15 | 685 |
| Rpl18 | 262 |
| Rps15a | -368 |
| Rpl36 | -379 |
| Rps12 | -530 |
| Rplp1 | -556 |
| Rps14 | -1429 |
| Rpl10 | -3718 |
| Rpl12 | -7477 |
CRMPS IN SEMA3A SIGNALING
| set | CRMPS IN SEMA3A SIGNALING |
| setSize | 16 |
| pANOVA | 0.000386 |
| s.dist | -0.513 |
| p.adjustANOVA | 0.00331 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Plxna4 | -7942 |
| Plxna3 | -7853 |
| Plxna1 | -7443 |
| Dpysl2 | -7162 |
| Crmp1 | -6319 |
| Dpysl4 | -6207 |
| Dpysl3 | -5935 |
| Dpysl5 | -5626 |
| Plxna2 | -4401 |
| Cdk5 | -4322 |
| Nrp1 | -3885 |
| Cdk5r1 | -2374 |
| Gsk3b | -1843 |
| Fes | -725 |
| Fyn | 236 |
| Sema3a | 874 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Plxna4 | -7942 |
| Plxna3 | -7853 |
| Plxna1 | -7443 |
| Dpysl2 | -7162 |
| Crmp1 | -6319 |
| Dpysl4 | -6207 |
| Dpysl3 | -5935 |
| Dpysl5 | -5626 |
| Plxna2 | -4401 |
| Cdk5 | -4322 |
| Nrp1 | -3885 |
| Cdk5r1 | -2374 |
| Gsk3b | -1843 |
| Fes | -725 |
| Fyn | 236 |
| Sema3a | 874 |
RESPIRATORY ELECTRON TRANSPORT
| set | RESPIRATORY ELECTRON TRANSPORT |
| setSize | 102 |
| pANOVA | 4.4e-19 |
| s.dist | 0.511 |
| p.adjustANOVA | 8.56e-17 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Coq10b | 8018 |
| Ndufb5 | 7945 |
| Ndufv2 | 7898 |
| Ndufc1 | 7880 |
| mt-Co1 | 7878 |
| Ndufaf4 | 7876 |
| mt-Nd4 | 7792 |
| Cox7a2l | 7767 |
| Sdhc | 7741 |
| mt-Nd3 | 7697 |
| mt-Nd6 | 7693 |
| mt-Nd1 | 7591 |
| Ndufa12 | 7567 |
| Ndufs4 | 7518 |
| Ndufs2 | 7517 |
| mt-Nd5 | 7515 |
| mt-Co2 | 7496 |
| Ndufa10 | 7482 |
| mt-Nd2 | 7442 |
| mt-Cytb | 7412 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Coq10b | 8018 |
| Ndufb5 | 7945 |
| Ndufv2 | 7898 |
| Ndufc1 | 7880 |
| mt-Co1 | 7878 |
| Ndufaf4 | 7876 |
| mt-Nd4 | 7792 |
| Cox7a2l | 7767 |
| Sdhc | 7741 |
| mt-Nd3 | 7697 |
| mt-Nd6 | 7693 |
| mt-Nd1 | 7591 |
| Ndufa12 | 7567 |
| Ndufs4 | 7518 |
| Ndufs2 | 7517 |
| mt-Nd5 | 7515 |
| mt-Co2 | 7496 |
| Ndufa10 | 7482 |
| mt-Nd2 | 7442 |
| mt-Cytb | 7412 |
| Timmdc1 | 7363 |
| Cycs | 7346 |
| Uqcrb | 7299 |
| mt-Co3 | 7285 |
| Ndufaf1 | 7142 |
| Ndufa5 | 7113 |
| Cox5a | 7098 |
| Surf1 | 7004 |
| Ndufa4 | 6928 |
| Ndufb9 | 6753 |
| Ndufaf6 | 6598 |
| Ndufb4 | 6560 |
| Cox6a1 | 6527 |
| Ndufb11 | 6480 |
| Ndufs1 | 6382 |
| Ndufaf2 | 6189 |
| Ndufb8 | 6188 |
| Sco2 | 6004 |
| Ndufs3 | 6002 |
| Ndufa13 | 5847 |
| Cox7c | 5830 |
| Ndufaf5 | 5686 |
| Ndufab1 | 5623 |
| Uqcrc2 | 5493 |
| Coq10a | 5366 |
| Cox20 | 5324 |
| Cox5b | 5289 |
| Sdha | 5222 |
| Sdhd | 5010 |
| Taco1 | 4977 |
| Cox6c | 4921 |
| Ndufc2 | 4817 |
| Ndufa6 | 4773 |
| Cox16 | 4727 |
| Ndufs5 | 4714 |
| Cox8a | 4559 |
| Ndufa7 | 4536 |
| Cox7b | 4525 |
| Sdhb | 4462 |
| Uqcrq | 4402 |
| Cox18 | 4188 |
| Ndufb6 | 4186 |
| Uqcrfs1 | 3897 |
| Ndufs6 | 3840 |
| Ndufv1 | 3475 |
| Ndufb1 | 3426 |
| Uqcrh | 3305 |
| Tmem126b | 3235 |
| Etfa | 3126 |
| Ndufa1 | 2823 |
| Ndufb3 | 2500 |
| Ecsit | 2348 |
| Cyc1 | 2328 |
| Ndufs7 | 2106 |
| Etfb | 2002 |
| Acad9 | 1991 |
| Cox6b1 | 1748 |
| Ndufa8 | 1700 |
| Ndufb7 | 1370 |
| Ndufb2 | 1235 |
| Etfdh | 1105 |
| Uqcr10 | 945 |
| Uqcrc1 | 826 |
| Cox4i1 | 421 |
| Ndufs8 | 350 |
| Ndufb10 | 315 |
| Ndufv3 | 202 |
| Sco1 | 89 |
| Nubpl | 24 |
| Ndufa3 | -187 |
| Trap1 | -275 |
| Uqcr11 | -884 |
| Ndufa11 | -921 |
| Ndufaf3 | -1144 |
| Ndufa9 | -1155 |
| Ndufaf7 | -1201 |
| Ndufa2 | -1362 |
| Cox14 | -2277 |
| Cox19 | -4426 |
| Lrpprc | -6916 |
| Cox11 | -7077 |
| Tmem186 | -7246 |
PI 3K CASCADE FGFR4
| set | PI 3K CASCADE FGFR4 |
| setSize | 10 |
| pANOVA | 0.00533 |
| s.dist | 0.509 |
| p.adjustANOVA | 0.0265 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Gab1 | 7497 |
| Fgf1 | 7468 |
| Pik3ca | 6280 |
| Fgf2 | 5929 |
| Frs2 | 4437 |
| Fgf9 | 4378 |
| Fgf18 | 3659 |
| Ptpn11 | 3578 |
| Grb2 | 1153 |
| Pik3r1 | -3940 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Gab1 | 7497 |
| Fgf1 | 7468 |
| Pik3ca | 6280 |
| Fgf2 | 5929 |
| Frs2 | 4437 |
| Fgf9 | 4378 |
| Fgf18 | 3659 |
| Ptpn11 | 3578 |
| Grb2 | 1153 |
| Pik3r1 | -3940 |
RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS
| set | RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS |
| setSize | 125 |
| pANOVA | 2.09e-22 |
| s.dist | 0.504 |
| p.adjustANOVA | 4.88e-20 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Coq10b | 8018 |
| Ndufb5 | 7945 |
| Atp5b | 7927 |
| Ndufv2 | 7898 |
| Ndufc1 | 7880 |
| mt-Co1 | 7878 |
| Ndufaf4 | 7876 |
| Atp5a1 | 7860 |
| mt-Nd4 | 7792 |
| Cox7a2l | 7767 |
| Sdhc | 7741 |
| mt-Nd3 | 7697 |
| mt-Nd6 | 7693 |
| Atp5c1 | 7596 |
| mt-Nd1 | 7591 |
| Ndufa12 | 7567 |
| Ndufs4 | 7518 |
| Ndufs2 | 7517 |
| mt-Nd5 | 7515 |
| mt-Co2 | 7496 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Coq10b | 8018 |
| Ndufb5 | 7945 |
| Atp5b | 7927 |
| Ndufv2 | 7898 |
| Ndufc1 | 7880 |
| mt-Co1 | 7878 |
| Ndufaf4 | 7876 |
| Atp5a1 | 7860 |
| mt-Nd4 | 7792 |
| Cox7a2l | 7767 |
| Sdhc | 7741 |
| mt-Nd3 | 7697 |
| mt-Nd6 | 7693 |
| Atp5c1 | 7596 |
| mt-Nd1 | 7591 |
| Ndufa12 | 7567 |
| Ndufs4 | 7518 |
| Ndufs2 | 7517 |
| mt-Nd5 | 7515 |
| mt-Co2 | 7496 |
| Ndufa10 | 7482 |
| mt-Nd2 | 7442 |
| mt-Cytb | 7412 |
| Timmdc1 | 7363 |
| Cycs | 7346 |
| Uqcrb | 7299 |
| mt-Co3 | 7285 |
| Atp5pb | 7223 |
| Ndufaf1 | 7142 |
| Ndufa5 | 7113 |
| Cox5a | 7098 |
| Surf1 | 7004 |
| Ndufa4 | 6928 |
| Slc25a14 | 6824 |
| Ndufb9 | 6753 |
| Ucp2 | 6711 |
| Ndufaf6 | 6598 |
| Ndufb4 | 6560 |
| mt-Atp6 | 6540 |
| Cox6a1 | 6527 |
| Ndufb11 | 6480 |
| mt-Atp8 | 6394 |
| Ndufs1 | 6382 |
| Ndufaf2 | 6189 |
| Ndufb8 | 6188 |
| Atp5h | 6056 |
| Sco2 | 6004 |
| Ndufs3 | 6002 |
| Ndufa13 | 5847 |
| Cox7c | 5830 |
| Ndufaf5 | 5686 |
| Ndufab1 | 5623 |
| Uqcrc2 | 5493 |
| Coq10a | 5366 |
| Cox20 | 5324 |
| Cox5b | 5289 |
| Sdha | 5222 |
| Sdhd | 5010 |
| Taco1 | 4977 |
| Cox6c | 4921 |
| Ndufc2 | 4817 |
| Ndufa6 | 4773 |
| Pm20d1 | 4762 |
| Cox16 | 4727 |
| Ndufs5 | 4714 |
| Cox8a | 4559 |
| Ndufa7 | 4536 |
| Cox7b | 4525 |
| Sdhb | 4462 |
| Uqcrq | 4402 |
| Atp5g3 | 4197 |
| Cox18 | 4188 |
| Ndufb6 | 4186 |
| Ucp3 | 4014 |
| Atp5o | 3981 |
| Uqcrfs1 | 3897 |
| Ndufs6 | 3840 |
| Atp5j | 3779 |
| Ndufv1 | 3475 |
| Ndufb1 | 3426 |
| Uqcrh | 3305 |
| Tmem126b | 3235 |
| Etfa | 3126 |
| Ndufa1 | 2823 |
| Dmac2l | 2814 |
| Ndufb3 | 2500 |
| Ecsit | 2348 |
| Cyc1 | 2328 |
| Ndufs7 | 2106 |
| Etfb | 2002 |
| Acad9 | 1991 |
| Atp5d | 1771 |
| Cox6b1 | 1748 |
| Atp5l | 1715 |
| Ndufa8 | 1700 |
| Atp5j2 | 1380 |
| Ndufb7 | 1370 |
| Atp5e | 1326 |
| Ndufb2 | 1235 |
| Etfdh | 1105 |
| Atp5g1 | 1065 |
| Uqcr10 | 945 |
| Uqcrc1 | 826 |
| Cox4i1 | 421 |
| Atp5k | 361 |
| Ndufs8 | 350 |
| Ndufb10 | 315 |
| Ndufv3 | 202 |
| Sco1 | 89 |
| Nubpl | 24 |
| Ndufa3 | -187 |
| Trap1 | -275 |
| Uqcr11 | -884 |
| Ndufa11 | -921 |
| Ndufaf3 | -1144 |
| Ndufa9 | -1155 |
| Ndufaf7 | -1201 |
| Ndufa2 | -1362 |
| Cox14 | -2277 |
| Atp5g2 | -3021 |
| Cox19 | -4426 |
| Slc25a27 | -6534 |
| Lrpprc | -6916 |
| Cox11 | -7077 |
| Tmem186 | -7246 |
PLATELET SENSITIZATION BY LDL
| set | PLATELET SENSITIZATION BY LDL |
| setSize | 15 |
| pANOVA | 0.000763 |
| s.dist | 0.502 |
| p.adjustANOVA | 0.00574 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Ppp2cb | 7901 |
| Ppp2r5a | 7828 |
| Ppp2r5b | 7716 |
| Pla2g4a | 7169 |
| Pecam1 | 6293 |
| Ppp2r5c | 6223 |
| Ppp2r5d | 6076 |
| Ppp2ca | 6009 |
| Ppp2r5e | 5887 |
| Ppp2r1a | 5786 |
| Ptpn6 | 5294 |
| Ptpn11 | 3578 |
| Ppp2r1b | -3521 |
| Mapk14 | -4078 |
| Lrp8 | -8388 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Ppp2cb | 7901 |
| Ppp2r5a | 7828 |
| Ppp2r5b | 7716 |
| Pla2g4a | 7169 |
| Pecam1 | 6293 |
| Ppp2r5c | 6223 |
| Ppp2r5d | 6076 |
| Ppp2ca | 6009 |
| Ppp2r5e | 5887 |
| Ppp2r1a | 5786 |
| Ptpn6 | 5294 |
| Ptpn11 | 3578 |
| Ppp2r1b | -3521 |
| Mapk14 | -4078 |
| Lrp8 | -8388 |
FRS MEDIATED FGFR3 SIGNALING
| set | FRS MEDIATED FGFR3 SIGNALING |
| setSize | 14 |
| pANOVA | 0.0012 |
| s.dist | 0.5 |
| p.adjustANOVA | 0.00819 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Fgfr3 | 7899 |
| Fgf1 | 7468 |
| Hras | 6145 |
| Fgf2 | 5929 |
| Kras | 5615 |
| Frs2 | 4437 |
| Fgf9 | 4378 |
| Nras | 3870 |
| Fgf18 | 3659 |
| Ptpn11 | 3578 |
| Frs3 | 2470 |
| Grb2 | 1153 |
| Sos1 | 678 |
| Fgf5 | -1717 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Fgfr3 | 7899 |
| Fgf1 | 7468 |
| Hras | 6145 |
| Fgf2 | 5929 |
| Kras | 5615 |
| Frs2 | 4437 |
| Fgf9 | 4378 |
| Nras | 3870 |
| Fgf18 | 3659 |
| Ptpn11 | 3578 |
| Frs3 | 2470 |
| Grb2 | 1153 |
| Sos1 | 678 |
| Fgf5 | -1717 |
SIGNALING BY FGFR3 FUSIONS IN CANCER
| set | SIGNALING BY FGFR3 FUSIONS IN CANCER |
| setSize | 10 |
| pANOVA | 0.00627 |
| s.dist | 0.499 |
| p.adjustANOVA | 0.0302 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Fgfr3 | 7899 |
| Gab1 | 7497 |
| Pik3ca | 6280 |
| Hras | 6145 |
| Kras | 5615 |
| Frs2 | 4437 |
| Nras | 3870 |
| Grb2 | 1153 |
| Sos1 | 678 |
| Pik3r1 | -3940 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Fgfr3 | 7899 |
| Gab1 | 7497 |
| Pik3ca | 6280 |
| Hras | 6145 |
| Kras | 5615 |
| Frs2 | 4437 |
| Nras | 3870 |
| Grb2 | 1153 |
| Sos1 | 678 |
| Pik3r1 | -3940 |
SHC MEDIATED CASCADE FGFR3
| set | SHC MEDIATED CASCADE FGFR3 |
| setSize | 12 |
| pANOVA | 0.00295 |
| s.dist | 0.496 |
| p.adjustANOVA | 0.0168 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Fgfr3 | 7899 |
| Fgf1 | 7468 |
| Hras | 6145 |
| Fgf2 | 5929 |
| Kras | 5615 |
| Fgf9 | 4378 |
| Nras | 3870 |
| Fgf18 | 3659 |
| Shc1 | 2133 |
| Grb2 | 1153 |
| Sos1 | 678 |
| Fgf5 | -1717 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Fgfr3 | 7899 |
| Fgf1 | 7468 |
| Hras | 6145 |
| Fgf2 | 5929 |
| Kras | 5615 |
| Fgf9 | 4378 |
| Nras | 3870 |
| Fgf18 | 3659 |
| Shc1 | 2133 |
| Grb2 | 1153 |
| Sos1 | 678 |
| Fgf5 | -1717 |
CITRIC ACID CYCLE TCA CYCLE
| set | CITRIC ACID CYCLE TCA CYCLE |
| setSize | 22 |
| pANOVA | 5.73e-05 |
| s.dist | 0.496 |
| p.adjustANOVA | 0.000662 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Idh3a | 7891 |
| Sdhc | 7741 |
| Suclg2 | 7070 |
| Sucla2 | 6896 |
| Idh2 | 6269 |
| Suclg1 | 5313 |
| Sdha | 5222 |
| Fh1 | 5179 |
| Sdhd | 5010 |
| Cs | 4982 |
| Dld | 4603 |
| Sdhb | 4462 |
| Aco2 | 4212 |
| Nnt | 4028 |
| Ogdh | 3796 |
| Mdh2 | 3697 |
| Me2 | 3462 |
| Fahd1 | 1568 |
| Me3 | 55 |
| Dlst | -353 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Idh3a | 7891 |
| Sdhc | 7741 |
| Suclg2 | 7070 |
| Sucla2 | 6896 |
| Idh2 | 6269 |
| Suclg1 | 5313 |
| Sdha | 5222 |
| Fh1 | 5179 |
| Sdhd | 5010 |
| Cs | 4982 |
| Dld | 4603 |
| Sdhb | 4462 |
| Aco2 | 4212 |
| Nnt | 4028 |
| Ogdh | 3796 |
| Mdh2 | 3697 |
| Me2 | 3462 |
| Fahd1 | 1568 |
| Me3 | 55 |
| Dlst | -353 |
| Idh3g | -2180 |
| Idh3b | -2460 |
SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES
| set | SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES |
| setSize | 29 |
| pANOVA | 4.04e-06 |
| s.dist | 0.494 |
| p.adjustANOVA | 8.43e-05 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Ube2r2 | 8021 |
| Ube2g1 | 7708 |
| Ube2l3 | 7108 |
| Ube2a | 6536 |
| Rps27a | 6289 |
| Ube2d2a | 6132 |
| Ube2d1 | 5984 |
| Ube2e3 | 5808 |
| Otulin | 5555 |
| Ube2e1 | 5418 |
| Ube2q2 | 5323 |
| Ube2w | 5307 |
| Ube2b | 5261 |
| Usp9x | 4844 |
| Uba52 | 4681 |
| Uba6 | 4676 |
| Ubb | 4464 |
| Ube2z | 4174 |
| Cdc34 | 3661 |
| Uchl3 | 3251 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Ube2r2 | 8021 |
| Ube2g1 | 7708 |
| Ube2l3 | 7108 |
| Ube2a | 6536 |
| Rps27a | 6289 |
| Ube2d2a | 6132 |
| Ube2d1 | 5984 |
| Ube2e3 | 5808 |
| Otulin | 5555 |
| Ube2e1 | 5418 |
| Ube2q2 | 5323 |
| Ube2w | 5307 |
| Ube2b | 5261 |
| Usp9x | 4844 |
| Uba52 | 4681 |
| Uba6 | 4676 |
| Ubb | 4464 |
| Ube2z | 4174 |
| Cdc34 | 3661 |
| Uchl3 | 3251 |
| Ube2h | 2616 |
| Usp5 | 2452 |
| Ube2k | 2136 |
| Ube2s | 841 |
| Uba1 | 320 |
| Ubc | -674 |
| Ube2t | -678 |
| Usp7 | -1723 |
| Ube2g2 | -1824 |
BLOOD GROUP SYSTEMS BIOSYNTHESIS
| set | BLOOD GROUP SYSTEMS BIOSYNTHESIS |
| setSize | 13 |
| pANOVA | 0.00205 |
| s.dist | 0.494 |
| p.adjustANOVA | 0.0128 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| St3gal4 | 8093 |
| B3galt5 | 6530 |
| B3galt2 | 6472 |
| St3gal6 | 5388 |
| B3galt1 | 5296 |
| Fut9 | 5237 |
| Fut11 | 4675 |
| Fut10 | 3979 |
| St6galnac6 | 3151 |
| Fut2 | 2114 |
| St3gal3 | 1139 |
| Fut4 | 842 |
| B3galt4 | -1986 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| St3gal4 | 8093 |
| B3galt5 | 6530 |
| B3galt2 | 6472 |
| St3gal6 | 5388 |
| B3galt1 | 5296 |
| Fut9 | 5237 |
| Fut11 | 4675 |
| Fut10 | 3979 |
| St6galnac6 | 3151 |
| Fut2 | 2114 |
| St3gal3 | 1139 |
| Fut4 | 842 |
| B3galt4 | -1986 |
SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE
| set | SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE |
| setSize | 106 |
| pANOVA | 2.7e-18 |
| s.dist | 0.49 |
| p.adjustANOVA | 3.15e-16 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Spcs1 | 7968 |
| Rps25 | 7859 |
| Rps9 | 7628 |
| Ssr3 | 7590 |
| Rpl23a | 7570 |
| Rpl24 | 7541 |
| Rps27l | 7478 |
| Rps8 | 7353 |
| Srp72 | 7265 |
| Rps3a1 | 7092 |
| Srp54a | 7058 |
| Rpl22l1 | 6947 |
| Sec11c | 6817 |
| Rps23 | 6816 |
| Rpl6 | 6754 |
| Rps4x | 6721 |
| Srpr | 6583 |
| Rpl23 | 6524 |
| Rps24 | 6393 |
| Rps7 | 6303 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Spcs1 | 7968 |
| Rps25 | 7859 |
| Rps9 | 7628 |
| Ssr3 | 7590 |
| Rpl23a | 7570 |
| Rpl24 | 7541 |
| Rps27l | 7478 |
| Rps8 | 7353 |
| Srp72 | 7265 |
| Rps3a1 | 7092 |
| Srp54a | 7058 |
| Rpl22l1 | 6947 |
| Sec11c | 6817 |
| Rps23 | 6816 |
| Rpl6 | 6754 |
| Rps4x | 6721 |
| Srpr | 6583 |
| Rpl23 | 6524 |
| Rps24 | 6393 |
| Rps7 | 6303 |
| Rps27a | 6289 |
| Rpl37a | 6191 |
| Rpl4 | 6149 |
| Rpl13a | 6125 |
| Ddost | 6106 |
| Spcs3 | 6041 |
| Rpl5 | 6040 |
| Rpl3 | 5937 |
| Rplp0 | 5892 |
| Rpl22 | 5878 |
| Rps29 | 5799 |
| Fau | 5748 |
| Rpl31 | 5694 |
| Srp9 | 5650 |
| Rpl17 | 5605 |
| Rpl14 | 5536 |
| Rps18 | 5497 |
| Rpl35a | 5485 |
| Spcs2 | 5474 |
| Srprb | 5461 |
| Rps20 | 5423 |
| Rpl18a | 5353 |
| Rps19 | 5332 |
| Rpl11 | 5303 |
| Rps26 | 5236 |
| Rpl27 | 5212 |
| Rpl30 | 5199 |
| Rpl9 | 5143 |
| Ssr1 | 5036 |
| Rpl7 | 5021 |
| Rps5 | 4951 |
| Rpl39 | 4874 |
| Uba52 | 4681 |
| Rpl32 | 4628 |
| Rpl35 | 4266 |
| Srp19 | 4116 |
| Ssr2 | 4054 |
| Rpl36a | 4039 |
| Rpl38 | 4000 |
| Rps28 | 3896 |
| Srp14 | 3837 |
| Rpl29 | 3664 |
| Rpl26 | 3635 |
| Rpl19 | 3569 |
| Rps11 | 3520 |
| Rpl34 | 3516 |
| Rpn2 | 3272 |
| Rpl13 | 3237 |
| Sec61g | 3230 |
| Rps21 | 3189 |
| Rpsa | 3114 |
| Rpl15 | 3021 |
| Rpl37 | 2954 |
| Rpl27a | 2792 |
| Rps17 | 2735 |
| Rpl21 | 2679 |
| Rpl8 | 2676 |
| Rpn1 | 2598 |
| Tram1 | 2539 |
| Rpl7a | 2289 |
| Rps27 | 2205 |
| Rps13 | 2151 |
| Sec61b | 2099 |
| Rps6 | 2047 |
| Rps16 | 1905 |
| Rpl36al | 1812 |
| Rps2 | 1413 |
| Rps3 | 1378 |
| Rps10 | 1099 |
| Rpl28 | 834 |
| Sec11a | 820 |
| Rplp2 | 776 |
| Rpl10a | 729 |
| Rps15 | 685 |
| Rpl18 | 262 |
| Ssr4 | -81 |
| Rps15a | -368 |
| Rpl36 | -379 |
| Rps12 | -530 |
| Rplp1 | -556 |
| Srp68 | -977 |
| Rps14 | -1429 |
| Rpl10 | -3718 |
| Sec61a1 | -5471 |
| Sec61a2 | -6161 |
| Rpl12 | -7477 |
PI 3K CASCADE FGFR3
| set | PI 3K CASCADE FGFR3 |
| setSize | 12 |
| pANOVA | 0.0033 |
| s.dist | 0.49 |
| p.adjustANOVA | 0.0182 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Fgfr3 | 7899 |
| Gab1 | 7497 |
| Fgf1 | 7468 |
| Pik3ca | 6280 |
| Fgf2 | 5929 |
| Frs2 | 4437 |
| Fgf9 | 4378 |
| Fgf18 | 3659 |
| Ptpn11 | 3578 |
| Grb2 | 1153 |
| Fgf5 | -1717 |
| Pik3r1 | -3940 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Fgfr3 | 7899 |
| Gab1 | 7497 |
| Fgf1 | 7468 |
| Pik3ca | 6280 |
| Fgf2 | 5929 |
| Frs2 | 4437 |
| Fgf9 | 4378 |
| Fgf18 | 3659 |
| Ptpn11 | 3578 |
| Grb2 | 1153 |
| Fgf5 | -1717 |
| Pik3r1 | -3940 |
TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS
| set | TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS |
| setSize | 15 |
| pANOVA | 0.00112 |
| s.dist | 0.486 |
| p.adjustANOVA | 0.00781 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Sox2 | 7747 |
| Smad4 | 6987 |
| Hhex | 6618 |
| Hif3a | 6507 |
| Sall1 | 6356 |
| Klf4 | 5976 |
| Fgf2 | 5929 |
| Epas1 | 3991 |
| Stat3 | 3876 |
| Tsc22d1 | 3292 |
| Smad2 | 3120 |
| Foxp1 | 2382 |
| Pbx1 | 580 |
| Zic3 | 417 |
| Nr6a1 | -6010 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Sox2 | 7747 |
| Smad4 | 6987 |
| Hhex | 6618 |
| Hif3a | 6507 |
| Sall1 | 6356 |
| Klf4 | 5976 |
| Fgf2 | 5929 |
| Epas1 | 3991 |
| Stat3 | 3876 |
| Tsc22d1 | 3292 |
| Smad2 | 3120 |
| Foxp1 | 2382 |
| Pbx1 | 580 |
| Zic3 | 417 |
| Nr6a1 | -6010 |
RHOBTB3 ATPASE CYCLE
| set | RHOBTB3 ATPASE CYCLE |
| setSize | 10 |
| pANOVA | 0.00804 |
| s.dist | 0.484 |
| p.adjustANOVA | 0.0369 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Plin3 | 7872 |
| Rhobtb3 | 7503 |
| Cul3 | 7452 |
| Rab9 | 6895 |
| Vhl | 5234 |
| Rab9b | 4734 |
| Lrrc41 | 2740 |
| Htr7 | 2254 |
| Hgs | 614 |
| Ccne1 | -6920 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Plin3 | 7872 |
| Rhobtb3 | 7503 |
| Cul3 | 7452 |
| Rab9 | 6895 |
| Vhl | 5234 |
| Rab9b | 4734 |
| Lrrc41 | 2740 |
| Htr7 | 2254 |
| Hgs | 614 |
| Ccne1 | -6920 |
FORMATION OF ATP BY CHEMIOSMOTIC COUPLING
| set | FORMATION OF ATP BY CHEMIOSMOTIC COUPLING |
| setSize | 18 |
| pANOVA | 0.000383 |
| s.dist | 0.483 |
| p.adjustANOVA | 0.00331 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Atp5b | 7927 |
| Atp5a1 | 7860 |
| Atp5c1 | 7596 |
| Atp5pb | 7223 |
| mt-Atp6 | 6540 |
| mt-Atp8 | 6394 |
| Atp5h | 6056 |
| Atp5g3 | 4197 |
| Atp5o | 3981 |
| Atp5j | 3779 |
| Dmac2l | 2814 |
| Atp5d | 1771 |
| Atp5l | 1715 |
| Atp5j2 | 1380 |
| Atp5e | 1326 |
| Atp5g1 | 1065 |
| Atp5k | 361 |
| Atp5g2 | -3021 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Atp5b | 7927 |
| Atp5a1 | 7860 |
| Atp5c1 | 7596 |
| Atp5pb | 7223 |
| mt-Atp6 | 6540 |
| mt-Atp8 | 6394 |
| Atp5h | 6056 |
| Atp5g3 | 4197 |
| Atp5o | 3981 |
| Atp5j | 3779 |
| Dmac2l | 2814 |
| Atp5d | 1771 |
| Atp5l | 1715 |
| Atp5j2 | 1380 |
| Atp5e | 1326 |
| Atp5g1 | 1065 |
| Atp5k | 361 |
| Atp5g2 | -3021 |
ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S
| set | ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S |
| setSize | 59 |
| pANOVA | 1.88e-10 |
| s.dist | 0.479 |
| p.adjustANOVA | 1e-08 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Rps25 | 7859 |
| Rps9 | 7628 |
| Rps27l | 7478 |
| Eif2s2 | 7386 |
| Eif2s1 | 7378 |
| Rps8 | 7353 |
| Eif3j2 | 7327 |
| Eif2s3x | 7322 |
| Rps3a1 | 7092 |
| Eif3e | 6910 |
| Eif3m | 6835 |
| Rps23 | 6816 |
| Rps4x | 6721 |
| Eif4e | 6694 |
| Pabpc1 | 6475 |
| Rps24 | 6393 |
| Rps7 | 6303 |
| Rps27a | 6289 |
| Eif4a2 | 5817 |
| Rps29 | 5799 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Rps25 | 7859 |
| Rps9 | 7628 |
| Rps27l | 7478 |
| Eif2s2 | 7386 |
| Eif2s1 | 7378 |
| Rps8 | 7353 |
| Eif3j2 | 7327 |
| Eif2s3x | 7322 |
| Rps3a1 | 7092 |
| Eif3e | 6910 |
| Eif3m | 6835 |
| Rps23 | 6816 |
| Rps4x | 6721 |
| Eif4e | 6694 |
| Pabpc1 | 6475 |
| Rps24 | 6393 |
| Rps7 | 6303 |
| Rps27a | 6289 |
| Eif4a2 | 5817 |
| Rps29 | 5799 |
| Eif3f | 5752 |
| Fau | 5748 |
| Rps18 | 5497 |
| Rps20 | 5423 |
| Eif3h | 5371 |
| Rps19 | 5332 |
| Rps26 | 5236 |
| Rps5 | 4951 |
| Eif4b | 4224 |
| Eif3g | 4203 |
| Rps28 | 3896 |
| Eif1ax | 3745 |
| Eif3l | 3736 |
| Rps11 | 3520 |
| Rps21 | 3189 |
| Eif4ebp1 | 3185 |
| Rpsa | 3114 |
| Eif3c | 2741 |
| Rps17 | 2735 |
| Eif3i | 2279 |
| Eif4a1 | 2228 |
| Rps27 | 2205 |
| Rps13 | 2151 |
| Rps6 | 2047 |
| Rps16 | 1905 |
| Eif3b | 1735 |
| Rps2 | 1413 |
| Rps3 | 1378 |
| Rps10 | 1099 |
| Rps15 | 685 |
| Eif3j1 | 347 |
| Eif3d | 142 |
| Rps15a | -368 |
| Rps12 | -530 |
| Eif4h | -1077 |
| Eif3k | -1122 |
| Rps14 | -1429 |
| Eif3a | -4677 |
| Eif4g1 | -6407 |
ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES
| set | ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES |
| setSize | 10 |
| pANOVA | 0.00907 |
| s.dist | 0.477 |
| p.adjustANOVA | 0.041 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Xbp1 | 7924 |
| Calr | 7911 |
| Hspa5 | 7750 |
| Nfyc | 6773 |
| Hsp90b1 | 6320 |
| Nfyb | 4929 |
| Ddit3 | 4263 |
| Atf6 | 1166 |
| Atf4 | -2108 |
| Nfya | -7171 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Xbp1 | 7924 |
| Calr | 7911 |
| Hspa5 | 7750 |
| Nfyc | 6773 |
| Hsp90b1 | 6320 |
| Nfyb | 4929 |
| Ddit3 | 4263 |
| Atf6 | 1166 |
| Atf4 | -2108 |
| Nfya | -7171 |
FATTY ACYL COA BIOSYNTHESIS
| set | FATTY ACYL COA BIOSYNTHESIS |
| setSize | 32 |
| pANOVA | 3.13e-06 |
| s.dist | 0.476 |
| p.adjustANOVA | 6.76e-05 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Elovl1 | 8118 |
| Scd2 | 8077 |
| Scd1 | 7998 |
| Hsd17b12 | 7867 |
| Elovl5 | 7775 |
| Hacd3 | 7770 |
| Acsbg1 | 7557 |
| Acsl3 | 7542 |
| Hacd1 | 7419 |
| Hacd2 | 7203 |
| Elovl4 | 6856 |
| Ppt1 | 6207 |
| Slc25a1 | 6127 |
| Acsl4 | 5773 |
| Elovl2 | 5589 |
| Tecr | 4332 |
| Acsl1 | 4283 |
| Acly | 3709 |
| Elovl7 | 3643 |
| Acsl6 | 3626 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Elovl1 | 8118 |
| Scd2 | 8077 |
| Scd1 | 7998 |
| Hsd17b12 | 7867 |
| Elovl5 | 7775 |
| Hacd3 | 7770 |
| Acsbg1 | 7557 |
| Acsl3 | 7542 |
| Hacd1 | 7419 |
| Hacd2 | 7203 |
| Elovl4 | 6856 |
| Ppt1 | 6207 |
| Slc25a1 | 6127 |
| Acsl4 | 5773 |
| Elovl2 | 5589 |
| Tecr | 4332 |
| Acsl1 | 4283 |
| Acly | 3709 |
| Elovl7 | 3643 |
| Acsl6 | 3626 |
| Cbr4 | 3573 |
| Rpp14 | 3564 |
| H2-Ke6 | 2049 |
| Elovl6 | 1439 |
| Fasn | 1074 |
| Ppt2 | 713 |
| Acaca | 149 |
| Hacd4 | -253 |
| Acsl5 | -955 |
| Slc27a3 | -5089 |
| Acsf3 | -5413 |
| Morc2a | -7768 |
FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES
| set | FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES |
| setSize | 17 |
| pANOVA | 0.000714 |
| s.dist | 0.474 |
| p.adjustANOVA | 0.00551 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Cav1 | 8036 |
| Btg1 | 8015 |
| Smad4 | 6987 |
| Mstn | 6804 |
| Cdkn1b | 6122 |
| Klf4 | 5976 |
| Ccng2 | 5737 |
| Rbl2 | 5406 |
| Foxg1 | 5262 |
| Foxo1 | 4368 |
| Smad3 | 3893 |
| Smad2 | 3120 |
| Pcbp4 | 3012 |
| Foxo3 | 1080 |
| Gadd45a | -2057 |
| Foxo4 | -3214 |
| Cdkn1a | -4737 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Cav1 | 8036 |
| Btg1 | 8015 |
| Smad4 | 6987 |
| Mstn | 6804 |
| Cdkn1b | 6122 |
| Klf4 | 5976 |
| Ccng2 | 5737 |
| Rbl2 | 5406 |
| Foxg1 | 5262 |
| Foxo1 | 4368 |
| Smad3 | 3893 |
| Smad2 | 3120 |
| Pcbp4 | 3012 |
| Foxo3 | 1080 |
| Gadd45a | -2057 |
| Foxo4 | -3214 |
| Cdkn1a | -4737 |
EUKARYOTIC TRANSLATION INITIATION
| set | EUKARYOTIC TRANSLATION INITIATION |
| setSize | 114 |
| pANOVA | 2.27e-18 |
| s.dist | 0.474 |
| p.adjustANOVA | 3.1e-16 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Rps25 | 7859 |
| Rps9 | 7628 |
| Rpl23a | 7570 |
| Rpl24 | 7541 |
| Rps27l | 7478 |
| Eif2s2 | 7386 |
| Eif2s1 | 7378 |
| Rps8 | 7353 |
| Eif3j2 | 7327 |
| Eif2s3x | 7322 |
| Rps3a1 | 7092 |
| Rpl22l1 | 6947 |
| Eif3e | 6910 |
| Eif3m | 6835 |
| Rps23 | 6816 |
| Rpl6 | 6754 |
| Rps4x | 6721 |
| Eif4e | 6694 |
| Rpl23 | 6524 |
| Pabpc1 | 6475 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Rps25 | 7859 |
| Rps9 | 7628 |
| Rpl23a | 7570 |
| Rpl24 | 7541 |
| Rps27l | 7478 |
| Eif2s2 | 7386 |
| Eif2s1 | 7378 |
| Rps8 | 7353 |
| Eif3j2 | 7327 |
| Eif2s3x | 7322 |
| Rps3a1 | 7092 |
| Rpl22l1 | 6947 |
| Eif3e | 6910 |
| Eif3m | 6835 |
| Rps23 | 6816 |
| Rpl6 | 6754 |
| Rps4x | 6721 |
| Eif4e | 6694 |
| Rpl23 | 6524 |
| Pabpc1 | 6475 |
| Rps24 | 6393 |
| Rps7 | 6303 |
| Rps27a | 6289 |
| Rpl37a | 6191 |
| Rpl4 | 6149 |
| Rpl13a | 6125 |
| Rpl5 | 6040 |
| Rpl3 | 5937 |
| Rplp0 | 5892 |
| Rpl22 | 5878 |
| Eif4a2 | 5817 |
| Rps29 | 5799 |
| Eif3f | 5752 |
| Fau | 5748 |
| Rpl31 | 5694 |
| Rpl17 | 5605 |
| Rpl14 | 5536 |
| Rps18 | 5497 |
| Rpl35a | 5485 |
| Eif5b | 5449 |
| Rps20 | 5423 |
| Eif3h | 5371 |
| Rpl18a | 5353 |
| Rps19 | 5332 |
| Rpl11 | 5303 |
| Rps26 | 5236 |
| Rpl27 | 5212 |
| Rpl30 | 5199 |
| Rpl9 | 5143 |
| Rpl7 | 5021 |
| Rps5 | 4951 |
| Eif5 | 4919 |
| Rpl39 | 4874 |
| Uba52 | 4681 |
| Rpl32 | 4628 |
| Eif2b2 | 4509 |
| Rpl35 | 4266 |
| Eif4b | 4224 |
| Eif3g | 4203 |
| Rpl36a | 4039 |
| Rpl38 | 4000 |
| Rps28 | 3896 |
| Eif1ax | 3745 |
| Eif3l | 3736 |
| Rpl29 | 3664 |
| Rpl26 | 3635 |
| Rpl19 | 3569 |
| Rps11 | 3520 |
| Rpl34 | 3516 |
| Eif2b5 | 3327 |
| Rpl13 | 3237 |
| Rps21 | 3189 |
| Eif4ebp1 | 3185 |
| Rpsa | 3114 |
| Rpl15 | 3021 |
| Eif2b4 | 3007 |
| Rpl37 | 2954 |
| Rpl27a | 2792 |
| Eif3c | 2741 |
| Rps17 | 2735 |
| Rpl21 | 2679 |
| Rpl8 | 2676 |
| Rpl7a | 2289 |
| Eif3i | 2279 |
| Eif4a1 | 2228 |
| Rps27 | 2205 |
| Rps13 | 2151 |
| Rps6 | 2047 |
| Rps16 | 1905 |
| Rpl36al | 1812 |
| Eif3b | 1735 |
| Rps2 | 1413 |
| Rps3 | 1378 |
| Rps10 | 1099 |
| Rpl28 | 834 |
| Rplp2 | 776 |
| Rpl10a | 729 |
| Rps15 | 685 |
| Eif3j1 | 347 |
| Rpl18 | 262 |
| Eif3d | 142 |
| Rps15a | -368 |
| Rpl36 | -379 |
| Rps12 | -530 |
| Rplp1 | -556 |
| Eif4h | -1077 |
| Eif3k | -1122 |
| Eif2b3 | -1343 |
| Rps14 | -1429 |
| Eif2b1 | -2157 |
| Rpl10 | -3718 |
| Eif3a | -4677 |
| Eif4g1 | -6407 |
| Rpl12 | -7477 |
PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR
| set | PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR |
| setSize | 16 |
| pANOVA | 0.00104 |
| s.dist | 0.473 |
| p.adjustANOVA | 0.00748 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Gng12 | 7807 |
| Gng10 | 7126 |
| Gng5 | 7048 |
| Gnb5 | 6693 |
| Gng11 | 6629 |
| Gng7 | 5131 |
| Gng3 | 4235 |
| Gngt2 | 2843 |
| Gnb4 | 2643 |
| Gng8 | 2078 |
| Gng4 | 2020 |
| Gng2 | 1559 |
| Gnb2 | 1365 |
| Gnas | 1269 |
| Gng13 | 922 |
| Gnb1 | 595 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Gng12 | 7807 |
| Gng10 | 7126 |
| Gng5 | 7048 |
| Gnb5 | 6693 |
| Gng11 | 6629 |
| Gng7 | 5131 |
| Gng3 | 4235 |
| Gngt2 | 2843 |
| Gnb4 | 2643 |
| Gng8 | 2078 |
| Gng4 | 2020 |
| Gng2 | 1559 |
| Gnb2 | 1365 |
| Gnas | 1269 |
| Gng13 | 922 |
| Gnb1 | 595 |
ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM
| set | ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM |
| setSize | 12 |
| pANOVA | 0.0047 |
| s.dist | 0.471 |
| p.adjustANOVA | 0.0243 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Elovl1 | 8118 |
| Elovl5 | 7775 |
| Scp2 | 7638 |
| Hsd17b4 | 7398 |
| Elovl2 | 5589 |
| Acox1 | 5295 |
| Fads2 | 4738 |
| Acsl1 | 4283 |
| Fads1 | 4278 |
| Acot8 | -1056 |
| Abcd1 | -2478 |
| Acaa1a | -6799 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Elovl1 | 8118 |
| Elovl5 | 7775 |
| Scp2 | 7638 |
| Hsd17b4 | 7398 |
| Elovl2 | 5589 |
| Acox1 | 5295 |
| Fads2 | 4738 |
| Acsl1 | 4283 |
| Fads1 | 4278 |
| Acot8 | -1056 |
| Abcd1 | -2478 |
| Acaa1a | -6799 |
RAS PROCESSING
| set | RAS PROCESSING |
| setSize | 23 |
| pANOVA | 9.41e-05 |
| s.dist | 0.47 |
| p.adjustANOVA | 0.000983 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Abhd17b | 7892 |
| Abhd17c | 7875 |
| Golga7 | 7402 |
| Fnta | 7324 |
| Zdhhc9 | 6876 |
| Bcl2l1 | 6712 |
| Rps27a | 6289 |
| Hras | 6145 |
| Lypla1 | 5861 |
| Kras | 5615 |
| Pde6d | 5594 |
| Calm1 | 5545 |
| Uba52 | 4681 |
| Ubb | 4464 |
| Abhd17a | 4112 |
| Nras | 3870 |
| Prkcq | 3125 |
| Prkg2 | 2321 |
| Ubc | -674 |
| Fntb | -1258 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Abhd17b | 7892 |
| Abhd17c | 7875 |
| Golga7 | 7402 |
| Fnta | 7324 |
| Zdhhc9 | 6876 |
| Bcl2l1 | 6712 |
| Rps27a | 6289 |
| Hras | 6145 |
| Lypla1 | 5861 |
| Kras | 5615 |
| Pde6d | 5594 |
| Calm1 | 5545 |
| Uba52 | 4681 |
| Ubb | 4464 |
| Abhd17a | 4112 |
| Nras | 3870 |
| Prkcq | 3125 |
| Prkg2 | 2321 |
| Ubc | -674 |
| Fntb | -1258 |
| Arl2 | -2071 |
| Rce1 | -4928 |
| Icmt | -7175 |
GLYCOGEN SYNTHESIS
| set | GLYCOGEN SYNTHESIS |
| setSize | 14 |
| pANOVA | 0.00241 |
| s.dist | 0.468 |
| p.adjustANOVA | 0.0144 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Pgm1 | 8125 |
| Ugp2 | 7605 |
| Gbe1 | 7451 |
| Gyg | 7284 |
| Rps27a | 6289 |
| Nhlrc1 | 5029 |
| Ppp1r3c | 4991 |
| Uba52 | 4681 |
| Ubb | 4464 |
| Gys1 | 3095 |
| Pgm2 | 725 |
| Pgm2l1 | -550 |
| Ubc | -674 |
| Epm2a | -6624 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Pgm1 | 8125 |
| Ugp2 | 7605 |
| Gbe1 | 7451 |
| Gyg | 7284 |
| Rps27a | 6289 |
| Nhlrc1 | 5029 |
| Ppp1r3c | 4991 |
| Uba52 | 4681 |
| Ubb | 4464 |
| Gys1 | 3095 |
| Pgm2 | 725 |
| Pgm2l1 | -550 |
| Ubc | -674 |
| Epm2a | -6624 |
THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT
| set | THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT |
| setSize | 172 |
| pANOVA | 3.22e-26 |
| s.dist | 0.468 |
| p.adjustANOVA | 1.25e-23 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Coq10b | 8018 |
| Pdk3 | 7974 |
| Ndufb5 | 7945 |
| Atp5b | 7927 |
| Ndufv2 | 7898 |
| Idh3a | 7891 |
| Ndufc1 | 7880 |
| mt-Co1 | 7878 |
| Ndufaf4 | 7876 |
| Atp5a1 | 7860 |
| mt-Nd4 | 7792 |
| Cox7a2l | 7767 |
| Sdhc | 7741 |
| mt-Nd3 | 7697 |
| mt-Nd6 | 7693 |
| Dlat | 7601 |
| Atp5c1 | 7596 |
| mt-Nd1 | 7591 |
| Ndufa12 | 7567 |
| Ndufs4 | 7518 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Coq10b | 8018 |
| Pdk3 | 7974 |
| Ndufb5 | 7945 |
| Atp5b | 7927 |
| Ndufv2 | 7898 |
| Idh3a | 7891 |
| Ndufc1 | 7880 |
| mt-Co1 | 7878 |
| Ndufaf4 | 7876 |
| Atp5a1 | 7860 |
| mt-Nd4 | 7792 |
| Cox7a2l | 7767 |
| Sdhc | 7741 |
| mt-Nd3 | 7697 |
| mt-Nd6 | 7693 |
| Dlat | 7601 |
| Atp5c1 | 7596 |
| mt-Nd1 | 7591 |
| Ndufa12 | 7567 |
| Ndufs4 | 7518 |
| Ndufs2 | 7517 |
| mt-Nd5 | 7515 |
| mt-Co2 | 7496 |
| Ndufa10 | 7482 |
| mt-Nd2 | 7442 |
| mt-Cytb | 7412 |
| Timmdc1 | 7363 |
| Cycs | 7346 |
| Uqcrb | 7299 |
| mt-Co3 | 7285 |
| Pdha1 | 7266 |
| Atp5pb | 7223 |
| Mpc1 | 7217 |
| Ndufaf1 | 7142 |
| Ndufa5 | 7113 |
| Cox5a | 7098 |
| Suclg2 | 7070 |
| Surf1 | 7004 |
| Ndufa4 | 6928 |
| Sucla2 | 6896 |
| Slc25a14 | 6824 |
| Ndufb9 | 6753 |
| Glo1 | 6717 |
| Ucp2 | 6711 |
| Ndufaf6 | 6598 |
| Ndufb4 | 6560 |
| mt-Atp6 | 6540 |
| Cox6a1 | 6527 |
| Ndufb11 | 6480 |
| mt-Atp8 | 6394 |
| Ndufs1 | 6382 |
| Rxra | 6291 |
| Idh2 | 6269 |
| Ndufaf2 | 6189 |
| Ndufb8 | 6188 |
| Atp5h | 6056 |
| Sco2 | 6004 |
| Ndufs3 | 6002 |
| Pdk4 | 5988 |
| Ldhb | 5923 |
| Vdac1 | 5872 |
| Ndufa13 | 5847 |
| Pdp1 | 5832 |
| Cox7c | 5830 |
| Me1 | 5759 |
| Ndufaf5 | 5686 |
| Ndufab1 | 5623 |
| Uqcrc2 | 5493 |
| Coq10a | 5366 |
| Mpc2 | 5349 |
| Cox20 | 5324 |
| Suclg1 | 5313 |
| Cox5b | 5289 |
| Sdha | 5222 |
| Fh1 | 5179 |
| Pdhb | 5144 |
| Sdhd | 5010 |
| Cs | 4982 |
| Taco1 | 4977 |
| Cox6c | 4921 |
| Pdhx | 4838 |
| Ndufc2 | 4817 |
| Ndufa6 | 4773 |
| Pm20d1 | 4762 |
| Cox16 | 4727 |
| Ndufs5 | 4714 |
| Dld | 4603 |
| Cox8a | 4559 |
| Ndufa7 | 4536 |
| Cox7b | 4525 |
| Adhfe1 | 4471 |
| Sdhb | 4462 |
| Uqcrq | 4402 |
| Aco2 | 4212 |
| Atp5g3 | 4197 |
| Cox18 | 4188 |
| Ndufb6 | 4186 |
| Slc16a1 | 4040 |
| Nnt | 4028 |
| Ucp3 | 4014 |
| Atp5o | 3981 |
| Uqcrfs1 | 3897 |
| Ndufs6 | 3840 |
| Ogdh | 3796 |
| Atp5j | 3779 |
| Mdh2 | 3697 |
| Ndufv1 | 3475 |
| Me2 | 3462 |
| Ndufb1 | 3426 |
| Bsg | 3346 |
| Uqcrh | 3305 |
| Ppard | 3263 |
| Tmem126b | 3235 |
| Etfa | 3126 |
| Ndufa1 | 2823 |
| Dmac2l | 2814 |
| Ndufb3 | 2500 |
| Ecsit | 2348 |
| Cyc1 | 2328 |
| Ndufs7 | 2106 |
| Etfb | 2002 |
| Acad9 | 1991 |
| Atp5d | 1771 |
| Cox6b1 | 1748 |
| Atp5l | 1715 |
| Ndufa8 | 1700 |
| Hagh | 1628 |
| Fahd1 | 1568 |
| Atp5j2 | 1380 |
| Ndufb7 | 1370 |
| Atp5e | 1326 |
| Ndufb2 | 1235 |
| Etfdh | 1105 |
| Atp5g1 | 1065 |
| Uqcr10 | 945 |
| Uqcrc1 | 826 |
| Cox4i1 | 421 |
| Atp5k | 361 |
| Ndufs8 | 350 |
| Pdk2 | 329 |
| Ndufb10 | 315 |
| Ndufv3 | 202 |
| Sco1 | 89 |
| Me3 | 55 |
| Nubpl | 24 |
| Ldha | -113 |
| Ndufa3 | -187 |
| Trap1 | -275 |
| Dlst | -353 |
| Uqcr11 | -884 |
| Ndufa11 | -921 |
| Ndufaf3 | -1144 |
| D2hgdh | -1145 |
| Ndufa9 | -1155 |
| Ndufaf7 | -1201 |
| Ndufa2 | -1362 |
| L2hgdh | -1917 |
| Slc16a3 | -1979 |
| Idh3g | -2180 |
| Cox14 | -2277 |
| Idh3b | -2460 |
| Pdpr | -2921 |
| Atp5g2 | -3021 |
| Gstz1 | -4292 |
| Cox19 | -4426 |
| Slc25a27 | -6534 |
| Lrpprc | -6916 |
| Pdp2 | -6931 |
| Cox11 | -7077 |
| Tmem186 | -7246 |
| Slc16a8 | -7495 |
| Pdk1 | -8282 |
RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY
| set | RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY |
| setSize | 94 |
| pANOVA | 4.86e-15 |
| s.dist | 0.467 |
| p.adjustANOVA | 4.36e-13 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Rps25 | 7859 |
| Rps9 | 7628 |
| Rpl23a | 7570 |
| Rpl24 | 7541 |
| Asns | 7505 |
| Rps27l | 7478 |
| Eif2s2 | 7386 |
| Eif2s1 | 7378 |
| Rps8 | 7353 |
| Eif2s3x | 7322 |
| Rps3a1 | 7092 |
| Rpl22l1 | 6947 |
| Rps23 | 6816 |
| Rpl6 | 6754 |
| Rps4x | 6721 |
| Rpl23 | 6524 |
| Rps24 | 6393 |
| Rps7 | 6303 |
| Rps27a | 6289 |
| Rpl37a | 6191 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Rps25 | 7859 |
| Rps9 | 7628 |
| Rpl23a | 7570 |
| Rpl24 | 7541 |
| Asns | 7505 |
| Rps27l | 7478 |
| Eif2s2 | 7386 |
| Eif2s1 | 7378 |
| Rps8 | 7353 |
| Eif2s3x | 7322 |
| Rps3a1 | 7092 |
| Rpl22l1 | 6947 |
| Rps23 | 6816 |
| Rpl6 | 6754 |
| Rps4x | 6721 |
| Rpl23 | 6524 |
| Rps24 | 6393 |
| Rps7 | 6303 |
| Rps27a | 6289 |
| Rpl37a | 6191 |
| Rpl4 | 6149 |
| Rpl13a | 6125 |
| Rpl5 | 6040 |
| Rpl3 | 5937 |
| Rplp0 | 5892 |
| Rpl22 | 5878 |
| Rps29 | 5799 |
| Fau | 5748 |
| Rpl31 | 5694 |
| Rpl17 | 5605 |
| Impact | 5556 |
| Rpl14 | 5536 |
| Rps18 | 5497 |
| Rpl35a | 5485 |
| Rps20 | 5423 |
| Rpl18a | 5353 |
| Rps19 | 5332 |
| Rpl11 | 5303 |
| Rps26 | 5236 |
| Rpl27 | 5212 |
| Rpl30 | 5199 |
| Rpl9 | 5143 |
| Rpl7 | 5021 |
| Rps5 | 4951 |
| Rpl39 | 4874 |
| Uba52 | 4681 |
| Rpl32 | 4628 |
| Cebpb | 4519 |
| Rpl35 | 4266 |
| Ddit3 | 4263 |
| Rpl36a | 4039 |
| Rpl38 | 4000 |
| Rps28 | 3896 |
| Rpl29 | 3664 |
| Rpl26 | 3635 |
| Rpl19 | 3569 |
| Rps11 | 3520 |
| Rpl34 | 3516 |
| Rpl13 | 3237 |
| Rps21 | 3189 |
| Rpsa | 3114 |
| Rpl15 | 3021 |
| Rpl37 | 2954 |
| Rpl27a | 2792 |
| Rps17 | 2735 |
| Rpl21 | 2679 |
| Rpl8 | 2676 |
| Rpl7a | 2289 |
| Rps27 | 2205 |
| Rps13 | 2151 |
| Rps6 | 2047 |
| Rps16 | 1905 |
| Rpl36al | 1812 |
| Atf2 | 1701 |
| Rps2 | 1413 |
| Rps3 | 1378 |
| Rps10 | 1099 |
| Rpl28 | 834 |
| Rplp2 | 776 |
| Rpl10a | 729 |
| Rps15 | 685 |
| Cebpg | 650 |
| Rpl18 | 262 |
| Rps15a | -368 |
| Rpl36 | -379 |
| Rps12 | -530 |
| Rplp1 | -556 |
| Atf3 | -1131 |
| Rps14 | -1429 |
| Atf4 | -2108 |
| Rpl10 | -3718 |
| Rpl12 | -7477 |
| Gcn1 | -7719 |
| Eif2ak4 | -8362 |
METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION
| set | METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION |
| setSize | 15 |
| pANOVA | 0.00196 |
| s.dist | 0.462 |
| p.adjustANOVA | 0.0124 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Cav1 | 8036 |
| Ddah1 | 7709 |
| Wasl | 7634 |
| Cygb | 5960 |
| Lypla1 | 5861 |
| Hsp90aa1 | 5564 |
| Calm1 | 5545 |
| Nostrin | 5532 |
| Ddah2 | 5415 |
| Akt1 | 1895 |
| Dnm2 | 1477 |
| Nosip | 1160 |
| Spr | 474 |
| Nos3 | 164 |
| Zdhhc21 | -7664 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Cav1 | 8036 |
| Ddah1 | 7709 |
| Wasl | 7634 |
| Cygb | 5960 |
| Lypla1 | 5861 |
| Hsp90aa1 | 5564 |
| Calm1 | 5545 |
| Nostrin | 5532 |
| Ddah2 | 5415 |
| Akt1 | 1895 |
| Dnm2 | 1477 |
| Nosip | 1160 |
| Spr | 474 |
| Nos3 | 164 |
| Zdhhc21 | -7664 |
G BETA GAMMA SIGNALLING THROUGH CDC42
| set | G BETA GAMMA SIGNALLING THROUGH CDC42 |
| setSize | 18 |
| pANOVA | 0.000773 |
| s.dist | 0.458 |
| p.adjustANOVA | 0.00574 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Gng12 | 7807 |
| Gng10 | 7126 |
| Gng5 | 7048 |
| Gnb5 | 6693 |
| Gng11 | 6629 |
| Cdc42 | 6362 |
| Gng7 | 5131 |
| Pak1 | 4489 |
| Gng3 | 4235 |
| Gngt2 | 2843 |
| Gnb4 | 2643 |
| Gng8 | 2078 |
| Gng4 | 2020 |
| Gng2 | 1559 |
| Gnb2 | 1365 |
| Gng13 | 922 |
| Gnb1 | 595 |
| Arhgef6 | -4424 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Gng12 | 7807 |
| Gng10 | 7126 |
| Gng5 | 7048 |
| Gnb5 | 6693 |
| Gng11 | 6629 |
| Cdc42 | 6362 |
| Gng7 | 5131 |
| Pak1 | 4489 |
| Gng3 | 4235 |
| Gngt2 | 2843 |
| Gnb4 | 2643 |
| Gng8 | 2078 |
| Gng4 | 2020 |
| Gng2 | 1559 |
| Gnb2 | 1365 |
| Gng13 | 922 |
| Gnb1 | 595 |
| Arhgef6 | -4424 |
METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS
| set | METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS |
| setSize | 10 |
| pANOVA | 0.0123 |
| s.dist | 0.457 |
| p.adjustANOVA | 0.0522 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Agt | 7607 |
| Ctsd | 7190 |
| Atp6ap2 | 6698 |
| Ctsz | 6131 |
| Anpep | 6061 |
| Ace2 | 5657 |
| Ace | 4119 |
| Mme | 3652 |
| Enpep | -4527 |
| Aopep | -6420 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Agt | 7607 |
| Ctsd | 7190 |
| Atp6ap2 | 6698 |
| Ctsz | 6131 |
| Anpep | 6061 |
| Ace2 | 5657 |
| Ace | 4119 |
| Mme | 3652 |
| Enpep | -4527 |
| Aopep | -6420 |
GLYCOGEN STORAGE DISEASES
| set | GLYCOGEN STORAGE DISEASES |
| setSize | 12 |
| pANOVA | 0.00645 |
| s.dist | 0.454 |
| p.adjustANOVA | 0.031 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Gbe1 | 7451 |
| Gyg | 7284 |
| Rps27a | 6289 |
| Nhlrc1 | 5029 |
| Ppp1r3c | 4991 |
| Uba52 | 4681 |
| Ubb | 4464 |
| Gaa | 3616 |
| G6pc3 | 3466 |
| Gys1 | 3095 |
| Ubc | -674 |
| Epm2a | -6624 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Gbe1 | 7451 |
| Gyg | 7284 |
| Rps27a | 6289 |
| Nhlrc1 | 5029 |
| Ppp1r3c | 4991 |
| Uba52 | 4681 |
| Ubb | 4464 |
| Gaa | 3616 |
| G6pc3 | 3466 |
| Gys1 | 3095 |
| Ubc | -674 |
| Epm2a | -6624 |
CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT
| set | CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT |
| setSize | 20 |
| pANOVA | 0.00044 |
| s.dist | 0.454 |
| p.adjustANOVA | 0.00367 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Slc25a17 | 8078 |
| Pex2 | 7871 |
| Atad1 | 7417 |
| Abcd3 | 7381 |
| Pex13 | 7008 |
| Fis1 | 7007 |
| Pex19 | 6868 |
| Abcd2 | 6375 |
| Gdap1 | 4775 |
| Acbd5 | 4667 |
| Pxmp2 | 3670 |
| Aldh3a2 | 3590 |
| Pex11b | 3173 |
| Pex3 | 1834 |
| Pex12 | 1617 |
| Pxmp4 | 1131 |
| Pex14 | -1275 |
| Pex16 | -1370 |
| Abcd1 | -2478 |
| Pex26 | -5622 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Slc25a17 | 8078 |
| Pex2 | 7871 |
| Atad1 | 7417 |
| Abcd3 | 7381 |
| Pex13 | 7008 |
| Fis1 | 7007 |
| Pex19 | 6868 |
| Abcd2 | 6375 |
| Gdap1 | 4775 |
| Acbd5 | 4667 |
| Pxmp2 | 3670 |
| Aldh3a2 | 3590 |
| Pex11b | 3173 |
| Pex3 | 1834 |
| Pex12 | 1617 |
| Pxmp4 | 1131 |
| Pex14 | -1275 |
| Pex16 | -1370 |
| Abcd1 | -2478 |
| Pex26 | -5622 |
PROTEIN METHYLATION
| set | PROTEIN METHYLATION |
| setSize | 17 |
| pANOVA | 0.00124 |
| s.dist | 0.452 |
| p.adjustANOVA | 0.00836 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Vcp | 7132 |
| Eef1a1 | 7065 |
| Camkmt | 5734 |
| Kin | 5706 |
| Calm1 | 5545 |
| Hspa8 | 5345 |
| Eef2 | 5251 |
| Prmt3 | 5088 |
| Eef1akmt1 | 4900 |
| Eef1akmt2 | 3788 |
| Mettl21a | 3587 |
| Etfb | 2002 |
| Rps2 | 1413 |
| Mettl22 | 1306 |
| Vcpkmt | 181 |
| Etfbkmt | -988 |
| Eef2kmt | -2298 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Vcp | 7132 |
| Eef1a1 | 7065 |
| Camkmt | 5734 |
| Kin | 5706 |
| Calm1 | 5545 |
| Hspa8 | 5345 |
| Eef2 | 5251 |
| Prmt3 | 5088 |
| Eef1akmt1 | 4900 |
| Eef1akmt2 | 3788 |
| Mettl21a | 3587 |
| Etfb | 2002 |
| Rps2 | 1413 |
| Mettl22 | 1306 |
| Vcpkmt | 181 |
| Etfbkmt | -988 |
| Eef2kmt | -2298 |
SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL
| set | SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL |
| setSize | 12 |
| pANOVA | 0.00692 |
| s.dist | 0.45 |
| p.adjustANOVA | 0.0325 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Scp2 | 7638 |
| Hsd3b7 | 7512 |
| Hsd17b4 | 7398 |
| Rxra | 6291 |
| Ptgis | 6080 |
| Cyp7b1 | 4729 |
| Cyp27a1 | 4439 |
| Slc27a2 | 2608 |
| Amacr | 2243 |
| Acot8 | -1056 |
| Ncoa2 | -2261 |
| Ncoa1 | -2935 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Scp2 | 7638 |
| Hsd3b7 | 7512 |
| Hsd17b4 | 7398 |
| Rxra | 6291 |
| Ptgis | 6080 |
| Cyp7b1 | 4729 |
| Cyp27a1 | 4439 |
| Slc27a2 | 2608 |
| Amacr | 2243 |
| Acot8 | -1056 |
| Ncoa2 | -2261 |
| Ncoa1 | -2935 |
ENOS ACTIVATION
| set | ENOS ACTIVATION |
| setSize | 11 |
| pANOVA | 0.01 |
| s.dist | 0.448 |
| p.adjustANOVA | 0.0443 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Cav1 | 8036 |
| Ddah1 | 7709 |
| Cygb | 5960 |
| Lypla1 | 5861 |
| Hsp90aa1 | 5564 |
| Calm1 | 5545 |
| Ddah2 | 5415 |
| Akt1 | 1895 |
| Spr | 474 |
| Nos3 | 164 |
| Zdhhc21 | -7664 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Cav1 | 8036 |
| Ddah1 | 7709 |
| Cygb | 5960 |
| Lypla1 | 5861 |
| Hsp90aa1 | 5564 |
| Calm1 | 5545 |
| Ddah2 | 5415 |
| Akt1 | 1895 |
| Spr | 474 |
| Nos3 | 164 |
| Zdhhc21 | -7664 |
DARPP 32 EVENTS
| set | DARPP 32 EVENTS |
| setSize | 23 |
| pANOVA | 0.000227 |
| s.dist | 0.444 |
| p.adjustANOVA | 0.00207 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Ppp2cb | 7901 |
| Prkar2b | 6991 |
| Ppp3r1 | 6925 |
| Ppp3ca | 6775 |
| Prkar2a | 6574 |
| Prkacb | 6523 |
| Ppp3cb | 6519 |
| Prkar1a | 6083 |
| Ppp2r5d | 6076 |
| Ppp2ca | 6009 |
| Ppp2r1a | 5786 |
| Pde4b | 5607 |
| Calm1 | 5545 |
| Ppp1r1b | 5019 |
| Ppp1ca | 4210 |
| Prkar1b | 3053 |
| Pde4c | 791 |
| Prkaca | 1 |
| Pde4a | -425 |
| Ppp2r1b | -3521 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Ppp2cb | 7901 |
| Prkar2b | 6991 |
| Ppp3r1 | 6925 |
| Ppp3ca | 6775 |
| Prkar2a | 6574 |
| Prkacb | 6523 |
| Ppp3cb | 6519 |
| Prkar1a | 6083 |
| Ppp2r5d | 6076 |
| Ppp2ca | 6009 |
| Ppp2r1a | 5786 |
| Pde4b | 5607 |
| Calm1 | 5545 |
| Ppp1r1b | 5019 |
| Ppp1ca | 4210 |
| Prkar1b | 3053 |
| Pde4c | 791 |
| Prkaca | 1 |
| Pde4a | -425 |
| Ppp2r1b | -3521 |
| Ppp3cc | -3743 |
| Pde4d | -3802 |
| Cdk5 | -4322 |
MITOPHAGY
| set | MITOPHAGY |
| setSize | 29 |
| pANOVA | 5.72e-05 |
| s.dist | 0.432 |
| p.adjustANOVA | 0.000662 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Tomm20 | 7699 |
| Fundc1 | 7516 |
| Tomm6 | 6889 |
| Atg5 | 6464 |
| Rps27a | 6289 |
| Map1lc3b | 5971 |
| Vdac1 | 5872 |
| Tomm22 | 5807 |
| Pink1 | 5613 |
| Tomm70a | 5591 |
| Sqstm1 | 5435 |
| Csnk2a1 | 4962 |
| Atg12 | 4936 |
| Uba52 | 4681 |
| Ubb | 4464 |
| Map1lc3a | 4293 |
| Mterf3 | 4098 |
| Prkn | 4078 |
| Csnk2b | 4025 |
| Tomm7 | 2401 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Tomm20 | 7699 |
| Fundc1 | 7516 |
| Tomm6 | 6889 |
| Atg5 | 6464 |
| Rps27a | 6289 |
| Map1lc3b | 5971 |
| Vdac1 | 5872 |
| Tomm22 | 5807 |
| Pink1 | 5613 |
| Tomm70a | 5591 |
| Sqstm1 | 5435 |
| Csnk2a1 | 4962 |
| Atg12 | 4936 |
| Uba52 | 4681 |
| Ubb | 4464 |
| Map1lc3a | 4293 |
| Mterf3 | 4098 |
| Prkn | 4078 |
| Csnk2b | 4025 |
| Tomm7 | 2401 |
| Pgam5 | 2303 |
| Tomm5 | 1994 |
| Tomm40 | 1049 |
| Mfn2 | -565 |
| Ubc | -674 |
| Mfn1 | -1475 |
| Csnk2a2 | -2248 |
| Ulk1 | -3161 |
| Src | -5726 |
CRISTAE FORMATION
| set | CRISTAE FORMATION |
| setSize | 31 |
| pANOVA | 3.31e-05 |
| s.dist | 0.431 |
| p.adjustANOVA | 0.000444 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Atp5b | 7927 |
| Atp5a1 | 7860 |
| Atp5c1 | 7596 |
| Immt | 7359 |
| Atp5pb | 7223 |
| Apoo | 6688 |
| mt-Atp6 | 6540 |
| mt-Atp8 | 6394 |
| Chchd3 | 6321 |
| Apool | 6097 |
| Atp5h | 6056 |
| Micos13 | 5293 |
| Hspa9 | 4467 |
| Atp5g3 | 4197 |
| Atp5o | 3981 |
| Atp5j | 3779 |
| Mtx2 | 3334 |
| Dmac2l | 2814 |
| Atp5d | 1771 |
| Atp5l | 1715 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Atp5b | 7927 |
| Atp5a1 | 7860 |
| Atp5c1 | 7596 |
| Immt | 7359 |
| Atp5pb | 7223 |
| Apoo | 6688 |
| mt-Atp6 | 6540 |
| mt-Atp8 | 6394 |
| Chchd3 | 6321 |
| Apool | 6097 |
| Atp5h | 6056 |
| Micos13 | 5293 |
| Hspa9 | 4467 |
| Atp5g3 | 4197 |
| Atp5o | 3981 |
| Atp5j | 3779 |
| Mtx2 | 3334 |
| Dmac2l | 2814 |
| Atp5d | 1771 |
| Atp5l | 1715 |
| Atp5j2 | 1380 |
| Atp5e | 1326 |
| Atp5g1 | 1065 |
| Micos10 | 1030 |
| Tmem11 | 547 |
| Atp5k | 361 |
| Chchd6 | -14 |
| Dnajc11 | -1025 |
| Mtx1 | -1760 |
| Samm50 | -2185 |
| Atp5g2 | -3021 |
SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX
| set | SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX |
| setSize | 13 |
| pANOVA | 0.00718 |
| s.dist | 0.431 |
| p.adjustANOVA | 0.0334 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Ptgds | 7969 |
| Ptgr2 | 6515 |
| Ptgis | 6080 |
| Ptges3 | 5826 |
| Ptgs1 | 5378 |
| Hpgd | 4922 |
| Hpgds | 4782 |
| Ptges | 4715 |
| Prxl2b | 4287 |
| Ptges2 | 1260 |
| Tbxas1 | 542 |
| Ptgs2 | -3990 |
| Cbr1 | -4167 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Ptgds | 7969 |
| Ptgr2 | 6515 |
| Ptgis | 6080 |
| Ptges3 | 5826 |
| Ptgs1 | 5378 |
| Hpgd | 4922 |
| Hpgds | 4782 |
| Ptges | 4715 |
| Prxl2b | 4287 |
| Ptges2 | 1260 |
| Tbxas1 | 542 |
| Ptgs2 | -3990 |
| Cbr1 | -4167 |
Here is the session info with all the versions of packages used.
sessionInfo()## R version 4.4.0 (2024-04-24)
## Platform: x86_64-pc-linux-gnu
## Running under: Ubuntu 22.04.4 LTS
##
## Matrix products: default
## BLAS: /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.10.0
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.10.0
##
## locale:
## [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
## [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8
## [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
## [7] LC_PAPER=en_US.UTF-8 LC_NAME=C
## [9] LC_ADDRESS=C LC_TELEPHONE=C
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
##
## time zone: Australia/Melbourne
## tzcode source: system (glibc)
##
## attached base packages:
## [1] stats4 stats graphics grDevices utils datasets methods
## [8] base
##
## other attached packages:
## [1] GGally_2.2.1 ggplot2_3.5.1
## [3] gtools_3.9.5 tibble_3.2.1
## [5] dplyr_1.1.4 echarts4r_0.4.5
## [7] beeswarm_0.4.0 pkgload_1.3.4
## [9] vioplot_0.4.0 sm_2.2-6.0
## [11] kableExtra_1.4.0 topconfects_1.20.0
## [13] limma_3.60.0 eulerr_7.0.2
## [15] mitch_1.16.0 MASS_7.3-60.2
## [17] fgsea_1.30.0 gplots_3.1.3.1
## [19] DESeq2_1.44.0 SummarizedExperiment_1.34.0
## [21] Biobase_2.64.0 MatrixGenerics_1.16.0
## [23] matrixStats_1.3.0 GenomicRanges_1.56.0
## [25] GenomeInfoDb_1.40.0 IRanges_2.38.0
## [27] S4Vectors_0.42.0 BiocGenerics_0.50.0
## [29] reshape2_1.4.4 zoo_1.8-12
##
## loaded via a namespace (and not attached):
## [1] bitops_1.0-7 gridExtra_2.3 rlang_1.1.4
## [4] magrittr_2.0.3 compiler_4.4.0 polylabelr_0.2.0
## [7] systemfonts_1.1.0 vctrs_0.6.5 stringr_1.5.1
## [10] pkgconfig_2.0.3 crayon_1.5.2 fastmap_1.2.0
## [13] XVector_0.44.0 labeling_0.4.3 caTools_1.18.2
## [16] utf8_1.2.4 promises_1.3.0 rmarkdown_2.27
## [19] UCSC.utils_1.0.0 purrr_1.0.2 xfun_0.44
## [22] zlibbioc_1.50.0 cachem_1.1.0 jsonlite_1.8.8
## [25] highr_0.11 later_1.3.2 DelayedArray_0.30.1
## [28] BiocParallel_1.38.0 parallel_4.4.0 R6_2.5.1
## [31] bslib_0.7.0 stringi_1.8.4 RColorBrewer_1.1-3
## [34] jquerylib_0.1.4 Rcpp_1.0.12 assertthat_0.2.1
## [37] knitr_1.47 httpuv_1.6.15 Matrix_1.7-0
## [40] tidyselect_1.2.1 rstudioapi_0.16.0 abind_1.4-5
## [43] yaml_2.3.8 codetools_0.2-20 lattice_0.22-6
## [46] plyr_1.8.9 withr_3.0.0 shiny_1.8.1.1
## [49] evaluate_0.23 polyclip_1.10-6 ggstats_0.6.0
## [52] xml2_1.3.6 pillar_1.9.0 KernSmooth_2.23-24
## [55] generics_0.1.3 munsell_0.5.1 scales_1.3.0
## [58] xtable_1.8-4 glue_1.7.0 tools_4.4.0
## [61] data.table_1.15.4 locfit_1.5-9.9 fastmatch_1.1-4
## [64] cowplot_1.1.3 grid_4.4.0 tidyr_1.3.1
## [67] colorspace_2.1-0 GenomeInfoDbData_1.2.12 cli_3.6.2
## [70] fansi_1.0.6 S4Arrays_1.4.0 viridisLite_0.4.2
## [73] svglite_2.1.3 gtable_0.3.5 sass_0.4.9
## [76] digest_0.6.35 SparseArray_1.4.3 farver_2.1.2
## [79] htmlwidgets_1.6.4 htmltools_0.5.8.1 lifecycle_1.0.4
## [82] httr_1.4.7 statmod_1.5.0 mime_0.12END of report