Mitch Report
Antony Kaspi & Mark Ziemann
date generated: 2024-06-04
Background
Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch
Input profiles
Here is the first few lines of the input profile.
| x | |
|---|---|
| 0610009B22Rik | 0.0259293 |
| 0610009E02Rik | 0.7519591 |
| 0610009L18Rik | -1.0644467 |
| 0610010K14Rik | 0.4476085 |
| 0610012G03Rik | -0.1633199 |
| 0610030E20Rik | -0.6249661 |
Here are some metrics about the input data profile:
| Profile metrics | |
|---|---|
| num_genesets | 1604 |
| num_genes_in_profile | 17595 |
| duplicated_genes_present | 0 |
| num_profile_genes_in_sets | 8418 |
| num_profile_genes_not_in_sets | 9177 |
Here is a plot of the input profiles. Note the dynamic ranges.
Here is the contour plot of the profile including all detected genes.
Input genesets
Here are some metrics about the gene sets used:
GMT file of genesets:| Gene sets metrics | |
|---|---|
| num_genesets | 1604 |
| num_genesets_excluded | 426 |
| num_genesets_included | 1178 |
Differential pathway expression
Interactive enrichment scatterplot
Significance is calculated by -log10(p-value). All points shown are FDR<0.05.
Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.
Results table
Top N= 50 gene sets| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | 19 | 9.30e-08 | 0.707 | 5.48e-06 |
| ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM | 12 | 2.63e-04 | 0.608 | 3.99e-03 |
| GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION | 12 | 5.67e-04 | 0.575 | 7.03e-03 |
| PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | 12 | 7.87e-04 | 0.560 | 9.09e-03 |
| RHOBTB3 ATPASE CYCLE | 10 | 2.44e-03 | 0.553 | 2.11e-02 |
| TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE | 13 | 8.34e-04 | 0.535 | 9.36e-03 |
| BBSOME MEDIATED CARGO TARGETING TO CILIUM | 23 | 9.26e-06 | 0.534 | 2.80e-04 |
| CITRIC ACID CYCLE TCA CYCLE | 22 | 3.36e-05 | 0.511 | 8.17e-04 |
| NUCLEOBASE BIOSYNTHESIS | 15 | 6.66e-04 | 0.507 | 8.01e-03 |
| KERATAN SULFATE BIOSYNTHESIS | 24 | 2.53e-05 | 0.497 | 6.48e-04 |
| COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 44 | 1.47e-08 | 0.494 | 1.15e-06 |
| COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING | 26 | 2.52e-05 | 0.477 | 6.48e-04 |
| HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR | 48 | 2.45e-08 | 0.465 | 1.70e-06 |
| KERATAN SULFATE KERATIN METABOLISM | 30 | 1.45e-05 | 0.457 | 4.07e-04 |
| CALNEXIN CALRETICULIN CYCLE | 26 | 5.88e-05 | 0.455 | 1.21e-03 |
| GLYCOGEN STORAGE DISEASES | 12 | 6.42e-03 | 0.454 | 4.23e-02 |
| GAP JUNCTION ASSEMBLY | 21 | 3.13e-04 | 0.454 | 4.61e-03 |
| ENDOSOMAL VACUOLAR PATHWAY | 10 | 1.31e-02 | -0.453 | 6.79e-02 |
| RETROGRADE NEUROTROPHIN SIGNALLING | 13 | 4.76e-03 | 0.452 | 3.38e-02 |
| GLYCOGEN SYNTHESIS | 14 | 3.62e-03 | 0.449 | 2.73e-02 |
| SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III | 23 | 2.64e-04 | 0.439 | 3.99e-03 |
| LDL CLEARANCE | 16 | 2.46e-03 | 0.437 | 2.12e-02 |
| CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX | 10 | 1.69e-02 | 0.436 | 7.96e-02 |
| OLFACTORY SIGNALING PATHWAY | 40 | 2.55e-06 | -0.430 | 1.11e-04 |
| RHO GTPASES ACTIVATE IQGAPS | 23 | 3.80e-04 | 0.428 | 5.20e-03 |
| RECEPTOR MEDIATED MITOPHAGY | 11 | 1.48e-02 | 0.424 | 7.47e-02 |
| PURINE SALVAGE | 12 | 1.14e-02 | 0.422 | 6.21e-02 |
| N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | 35 | 1.73e-05 | 0.420 | 4.74e-04 |
| CD28 DEPENDENT VAV1 PATHWAY | 11 | 1.64e-02 | 0.418 | 7.89e-02 |
| ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | 11 | 1.65e-02 | 0.417 | 7.89e-02 |
| N GLYCAN ANTENNAE ELONGATION | 15 | 5.18e-03 | 0.417 | 3.55e-02 |
| TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX | 12 | 1.24e-02 | 0.417 | 6.53e-02 |
| WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 | 13 | 9.63e-03 | 0.415 | 5.43e-02 |
| SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL | 10 | 2.35e-02 | 0.414 | 1.00e-01 |
| GLYCOGEN METABOLISM | 25 | 3.52e-04 | 0.413 | 4.99e-03 |
| REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS | 14 | 8.17e-03 | 0.408 | 4.91e-02 |
| CYTOSOLIC TRNA AMINOACYLATION | 24 | 5.41e-04 | 0.408 | 6.92e-03 |
| INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE | 22 | 9.55e-04 | 0.407 | 1.05e-02 |
| GLYCOSPHINGOLIPID METABOLISM | 38 | 1.44e-05 | 0.407 | 4.07e-04 |
| WNT LIGAND BIOGENESIS AND TRAFFICKING | 21 | 1.61e-03 | 0.398 | 1.57e-02 |
| SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | 20 | 2.10e-03 | 0.397 | 1.91e-02 |
| GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | 14 | 1.08e-02 | 0.394 | 5.95e-02 |
| SUPPRESSION OF PHAGOSOMAL MATURATION | 12 | 1.83e-02 | 0.394 | 8.37e-02 |
| CS DS DEGRADATION | 14 | 1.23e-02 | 0.386 | 6.52e-02 |
| IRE1ALPHA ACTIVATES CHAPERONES | 50 | 2.68e-06 | 0.384 | 1.12e-04 |
| KERATAN SULFATE DEGRADATION | 11 | 2.84e-02 | 0.382 | 1.14e-01 |
| ACTIVATION OF AMPK DOWNSTREAM OF NMDARS | 20 | 3.35e-03 | 0.379 | 2.62e-02 |
| RECYCLING PATHWAY OF L1 | 40 | 3.40e-05 | 0.379 | 8.17e-04 |
| POST CHAPERONIN TUBULIN FOLDING PATHWAY | 17 | 7.01e-03 | 0.378 | 4.49e-02 |
| COPI MEDIATED ANTEROGRADE TRANSPORT | 91 | 5.74e-10 | 0.376 | 5.21e-08 |
Results (complete table)
Click HERE to show results for all gene sets
| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | 19 | 9.30e-08 | 7.07e-01 | 5.48e-06 |
| ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM | 12 | 2.63e-04 | 6.08e-01 | 3.99e-03 |
| GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION | 12 | 5.67e-04 | 5.75e-01 | 7.03e-03 |
| PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | 12 | 7.87e-04 | 5.60e-01 | 9.09e-03 |
| RHOBTB3 ATPASE CYCLE | 10 | 2.44e-03 | 5.53e-01 | 2.11e-02 |
| TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE | 13 | 8.34e-04 | 5.35e-01 | 9.36e-03 |
| BBSOME MEDIATED CARGO TARGETING TO CILIUM | 23 | 9.26e-06 | 5.34e-01 | 2.80e-04 |
| CITRIC ACID CYCLE TCA CYCLE | 22 | 3.36e-05 | 5.11e-01 | 8.17e-04 |
| NUCLEOBASE BIOSYNTHESIS | 15 | 6.66e-04 | 5.07e-01 | 8.01e-03 |
| KERATAN SULFATE BIOSYNTHESIS | 24 | 2.53e-05 | 4.97e-01 | 6.48e-04 |
| COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 44 | 1.47e-08 | 4.94e-01 | 1.15e-06 |
| COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING | 26 | 2.52e-05 | 4.77e-01 | 6.48e-04 |
| HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR | 48 | 2.45e-08 | 4.65e-01 | 1.70e-06 |
| KERATAN SULFATE KERATIN METABOLISM | 30 | 1.45e-05 | 4.57e-01 | 4.07e-04 |
| CALNEXIN CALRETICULIN CYCLE | 26 | 5.88e-05 | 4.55e-01 | 1.21e-03 |
| GLYCOGEN STORAGE DISEASES | 12 | 6.42e-03 | 4.54e-01 | 4.23e-02 |
| GAP JUNCTION ASSEMBLY | 21 | 3.13e-04 | 4.54e-01 | 4.61e-03 |
| ENDOSOMAL VACUOLAR PATHWAY | 10 | 1.31e-02 | -4.53e-01 | 6.79e-02 |
| RETROGRADE NEUROTROPHIN SIGNALLING | 13 | 4.76e-03 | 4.52e-01 | 3.38e-02 |
| GLYCOGEN SYNTHESIS | 14 | 3.62e-03 | 4.49e-01 | 2.73e-02 |
| SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III | 23 | 2.64e-04 | 4.39e-01 | 3.99e-03 |
| LDL CLEARANCE | 16 | 2.46e-03 | 4.37e-01 | 2.12e-02 |
| CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX | 10 | 1.69e-02 | 4.36e-01 | 7.96e-02 |
| OLFACTORY SIGNALING PATHWAY | 40 | 2.55e-06 | -4.30e-01 | 1.11e-04 |
| RHO GTPASES ACTIVATE IQGAPS | 23 | 3.80e-04 | 4.28e-01 | 5.20e-03 |
| RECEPTOR MEDIATED MITOPHAGY | 11 | 1.48e-02 | 4.24e-01 | 7.47e-02 |
| PURINE SALVAGE | 12 | 1.14e-02 | 4.22e-01 | 6.21e-02 |
| N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | 35 | 1.73e-05 | 4.20e-01 | 4.74e-04 |
| CD28 DEPENDENT VAV1 PATHWAY | 11 | 1.64e-02 | 4.18e-01 | 7.89e-02 |
| ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | 11 | 1.65e-02 | 4.17e-01 | 7.89e-02 |
| N GLYCAN ANTENNAE ELONGATION | 15 | 5.18e-03 | 4.17e-01 | 3.55e-02 |
| TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX | 12 | 1.24e-02 | 4.17e-01 | 6.53e-02 |
| WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 | 13 | 9.63e-03 | 4.15e-01 | 5.43e-02 |
| SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL | 10 | 2.35e-02 | 4.14e-01 | 1.00e-01 |
| GLYCOGEN METABOLISM | 25 | 3.52e-04 | 4.13e-01 | 4.99e-03 |
| REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS | 14 | 8.17e-03 | 4.08e-01 | 4.91e-02 |
| CYTOSOLIC TRNA AMINOACYLATION | 24 | 5.41e-04 | 4.08e-01 | 6.92e-03 |
| INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE | 22 | 9.55e-04 | 4.07e-01 | 1.05e-02 |
| GLYCOSPHINGOLIPID METABOLISM | 38 | 1.44e-05 | 4.07e-01 | 4.07e-04 |
| WNT LIGAND BIOGENESIS AND TRAFFICKING | 21 | 1.61e-03 | 3.98e-01 | 1.57e-02 |
| SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | 20 | 2.10e-03 | 3.97e-01 | 1.91e-02 |
| GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | 14 | 1.08e-02 | 3.94e-01 | 5.95e-02 |
| SUPPRESSION OF PHAGOSOMAL MATURATION | 12 | 1.83e-02 | 3.94e-01 | 8.37e-02 |
| CS DS DEGRADATION | 14 | 1.23e-02 | 3.86e-01 | 6.52e-02 |
| IRE1ALPHA ACTIVATES CHAPERONES | 50 | 2.68e-06 | 3.84e-01 | 1.12e-04 |
| KERATAN SULFATE DEGRADATION | 11 | 2.84e-02 | 3.82e-01 | 1.14e-01 |
| ACTIVATION OF AMPK DOWNSTREAM OF NMDARS | 20 | 3.35e-03 | 3.79e-01 | 2.62e-02 |
| RECYCLING PATHWAY OF L1 | 40 | 3.40e-05 | 3.79e-01 | 8.17e-04 |
| POST CHAPERONIN TUBULIN FOLDING PATHWAY | 17 | 7.01e-03 | 3.78e-01 | 4.49e-02 |
| COPI MEDIATED ANTEROGRADE TRANSPORT | 91 | 5.74e-10 | 3.76e-01 | 5.21e-08 |
| BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS | 11 | 3.32e-02 | 3.71e-01 | 1.30e-01 |
| RESPONSE OF MTB TO PHAGOCYTOSIS | 21 | 3.30e-03 | 3.70e-01 | 2.59e-02 |
| CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE | 49 | 7.32e-06 | 3.70e-01 | 2.33e-04 |
| ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 | 10 | 4.50e-02 | 3.66e-01 | 1.60e-01 |
| INTERFERON ALPHA BETA SIGNALING | 53 | 4.93e-06 | -3.63e-01 | 1.71e-04 |
| BRANCHED CHAIN AMINO ACID CATABOLISM | 21 | 4.41e-03 | 3.59e-01 | 3.19e-02 |
| N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | 24 | 2.43e-03 | 3.58e-01 | 2.11e-02 |
| ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES | 10 | 5.15e-02 | 3.56e-01 | 1.75e-01 |
| KILLING MECHANISMS | 11 | 4.22e-02 | -3.54e-01 | 1.53e-01 |
| VLDLR INTERNALISATION AND DEGRADATION | 12 | 3.50e-02 | 3.52e-01 | 1.33e-01 |
| GAP JUNCTION TRAFFICKING AND REGULATION | 33 | 4.83e-04 | 3.51e-01 | 6.32e-03 |
| ER QUALITY CONTROL COMPARTMENT ERQC | 21 | 5.65e-03 | 3.49e-01 | 3.82e-02 |
| ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA | 15 | 1.98e-02 | 3.47e-01 | 8.84e-02 |
| GOLGI TO ER RETROGRADE TRANSPORT | 119 | 5.98e-11 | 3.47e-01 | 1.01e-08 |
| INSULIN PROCESSING | 24 | 3.26e-03 | 3.47e-01 | 2.58e-02 |
| SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES | 29 | 1.25e-03 | 3.46e-01 | 1.30e-02 |
| ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | 38 | 2.33e-04 | 3.45e-01 | 3.66e-03 |
| FATTY ACYL COA BIOSYNTHESIS | 32 | 7.81e-04 | 3.43e-01 | 9.09e-03 |
| SULFUR AMINO ACID METABOLISM | 23 | 4.77e-03 | 3.40e-01 | 3.38e-02 |
| AGGREPHAGY | 35 | 5.22e-04 | 3.39e-01 | 6.76e-03 |
| HYALURONAN UPTAKE AND DEGRADATION | 11 | 5.32e-02 | 3.37e-01 | 1.78e-01 |
| NUCLEAR ENVELOPE NE REASSEMBLY | 64 | 3.78e-06 | 3.34e-01 | 1.39e-04 |
| MATURATION OF SARS COV 2 SPIKE PROTEIN | 29 | 1.90e-03 | 3.33e-01 | 1.77e-02 |
| DERMATAN SULFATE BIOSYNTHESIS | 11 | 5.65e-02 | 3.32e-01 | 1.87e-01 |
| INTRAFLAGELLAR TRANSPORT | 52 | 3.48e-05 | 3.32e-01 | 8.20e-04 |
| GLUCONEOGENESIS | 27 | 2.84e-03 | 3.32e-01 | 2.34e-02 |
| INFECTION WITH MYCOBACTERIUM TUBERCULOSIS | 24 | 4.91e-03 | 3.32e-01 | 3.43e-02 |
| THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS | 27 | 3.27e-03 | 3.27e-01 | 2.58e-02 |
| INSULIN RECEPTOR RECYCLING | 20 | 1.18e-02 | 3.25e-01 | 6.40e-02 |
| PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | 51 | 6.18e-05 | 3.24e-01 | 1.21e-03 |
| HSF1 ACTIVATION | 25 | 5.37e-03 | 3.22e-01 | 3.65e-02 |
| SPRY REGULATION OF FGF SIGNALING | 16 | 2.59e-02 | 3.22e-01 | 1.06e-01 |
| GLUTAMATE AND GLUTAMINE METABOLISM | 13 | 4.53e-02 | 3.21e-01 | 1.61e-01 |
| TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | 171 | 5.64e-13 | 3.20e-01 | 1.33e-10 |
| DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM | 39 | 5.53e-04 | 3.20e-01 | 7.00e-03 |
| LYSOSOME VESICLE BIOGENESIS | 33 | 1.52e-03 | 3.19e-01 | 1.53e-02 |
| MATURATION OF NUCLEOPROTEIN | 10 | 8.29e-02 | -3.17e-01 | 2.42e-01 |
| INITIATION OF NUCLEAR ENVELOPE NE REFORMATION | 17 | 2.42e-02 | 3.16e-01 | 1.02e-01 |
| MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | 15 | 3.47e-02 | -3.15e-01 | 1.32e-01 |
| ER TO GOLGI ANTEROGRADE TRANSPORT | 142 | 1.21e-10 | 3.13e-01 | 1.48e-08 |
| PEROXISOMAL LIPID METABOLISM | 27 | 4.91e-03 | 3.13e-01 | 3.43e-02 |
| PROTEIN METHYLATION | 17 | 2.56e-02 | 3.13e-01 | 1.06e-01 |
| COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 86 | 5.84e-07 | 3.12e-01 | 2.99e-05 |
| MHC CLASS II ANTIGEN PRESENTATION | 102 | 5.59e-08 | 3.11e-01 | 3.46e-06 |
| RAF ACTIVATION | 34 | 1.68e-03 | 3.11e-01 | 1.63e-02 |
| CTLA4 INHIBITORY SIGNALING | 20 | 1.65e-02 | 3.10e-01 | 7.89e-02 |
| RAP1 SIGNALLING | 15 | 3.79e-02 | 3.10e-01 | 1.40e-01 |
| TRNA AMINOACYLATION | 42 | 5.61e-04 | 3.08e-01 | 7.03e-03 |
| APOPTOSIS INDUCED DNA FRAGMENTATION | 10 | 9.43e-02 | -3.06e-01 | 2.66e-01 |
| HSF1 DEPENDENT TRANSACTIVATION | 33 | 2.39e-03 | 3.06e-01 | 2.10e-02 |
| KSRP KHSRP BINDS AND DESTABILIZES MRNA | 16 | 3.46e-02 | -3.05e-01 | 1.32e-01 |
| ASPARTATE AND ASPARAGINE METABOLISM | 10 | 9.79e-02 | 3.02e-01 | 2.72e-01 |
| GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | 30 | 4.23e-03 | 3.02e-01 | 3.08e-02 |
| SPHINGOLIPID METABOLISM | 80 | 3.32e-06 | 3.01e-01 | 1.26e-04 |
| ADENYLATE CYCLASE INHIBITORY PATHWAY | 13 | 6.11e-02 | 3.00e-01 | 1.96e-01 |
| SELECTIVE AUTOPHAGY | 72 | 1.10e-05 | 3.00e-01 | 3.23e-04 |
| EPHRIN SIGNALING | 19 | 2.41e-02 | 2.99e-01 | 1.02e-01 |
| DARPP 32 EVENTS | 23 | 1.32e-02 | 2.99e-01 | 6.81e-02 |
| PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING | 11 | 8.64e-02 | -2.99e-01 | 2.49e-01 |
| CARGO CONCENTRATION IN THE ER | 31 | 4.20e-03 | 2.97e-01 | 3.08e-02 |
| NUCLEOTIDE LIKE PURINERGIC RECEPTORS | 13 | 6.65e-02 | 2.94e-01 | 2.08e-01 |
| CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE | 11 | 9.14e-02 | 2.94e-01 | 2.60e-01 |
| VEGFR2 MEDIATED VASCULAR PERMEABILITY | 27 | 8.68e-03 | 2.92e-01 | 5.13e-02 |
| ASPARAGINE N LINKED GLYCOSYLATION | 285 | 2.63e-17 | 2.91e-01 | 1.55e-14 |
| PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES | 13 | 6.90e-02 | 2.91e-01 | 2.13e-01 |
| PEROXISOMAL PROTEIN IMPORT | 59 | 1.12e-04 | 2.91e-01 | 2.06e-03 |
| RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA | 25 | 1.21e-02 | -2.90e-01 | 6.45e-02 |
| ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 | 20 | 2.52e-02 | 2.89e-01 | 1.05e-01 |
| HDMS DEMETHYLATE HISTONES | 30 | 6.21e-03 | -2.89e-01 | 4.16e-02 |
| CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN | 36 | 2.75e-03 | 2.88e-01 | 2.30e-02 |
| REGULATION OF MECP2 EXPRESSION AND ACTIVITY | 29 | 7.81e-03 | -2.85e-01 | 4.80e-02 |
| PKA MEDIATED PHOSPHORYLATION OF CREB | 19 | 3.13e-02 | 2.85e-01 | 1.24e-01 |
| NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | 14 | 6.46e-02 | 2.85e-01 | 2.02e-01 |
| IRON UPTAKE AND TRANSPORT | 51 | 4.51e-04 | 2.84e-01 | 5.97e-03 |
| TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST | 15 | 5.72e-02 | 2.84e-01 | 1.88e-01 |
| DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS | 59 | 1.70e-04 | 2.83e-01 | 2.93e-03 |
| AUTOPHAGY | 139 | 9.69e-09 | 2.82e-01 | 8.15e-07 |
| COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING | 36 | 3.56e-03 | 2.81e-01 | 2.73e-02 |
| ACYL CHAIN REMODELLING OF PE | 17 | 4.77e-02 | 2.77e-01 | 1.66e-01 |
| SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | 16 | 5.49e-02 | 2.77e-01 | 1.83e-01 |
| INTERFERON GAMMA SIGNALING | 74 | 3.77e-05 | -2.77e-01 | 8.71e-04 |
| RAB GERANYLGERANYLATION | 57 | 3.60e-04 | 2.73e-01 | 5.05e-03 |
| PKMTS METHYLATE HISTONE LYSINES | 51 | 7.49e-04 | -2.73e-01 | 8.82e-03 |
| LYSINE CATABOLISM | 11 | 1.18e-01 | 2.72e-01 | 3.07e-01 |
| SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | 13 | 8.98e-02 | 2.72e-01 | 2.57e-01 |
| RESOLUTION OF D LOOP STRUCTURES | 31 | 9.13e-03 | -2.71e-01 | 5.24e-02 |
| CHOLESTEROL BIOSYNTHESIS | 24 | 2.19e-02 | 2.70e-01 | 9.61e-02 |
| RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION | 54 | 5.96e-04 | -2.70e-01 | 7.24e-03 |
| GAP JUNCTION DEGRADATION | 11 | 1.21e-01 | 2.70e-01 | 3.11e-01 |
| COPII MEDIATED VESICLE TRANSPORT | 66 | 1.69e-04 | 2.68e-01 | 2.93e-03 |
| THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT | 66 | 1.72e-04 | 2.67e-01 | 2.93e-03 |
| SIGNAL AMPLIFICATION | 31 | 1.00e-02 | 2.67e-01 | 5.58e-02 |
| GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK | 16 | 6.42e-02 | 2.67e-01 | 2.02e-01 |
| DEGRADATION OF CYSTEINE AND HOMOCYSTEINE | 13 | 9.57e-02 | 2.67e-01 | 2.69e-01 |
| INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | 13 | 9.60e-02 | 2.67e-01 | 2.69e-01 |
| INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC | 185 | 4.85e-10 | 2.65e-01 | 4.76e-08 |
| BUDDING AND MATURATION OF HIV VIRION | 27 | 1.71e-02 | 2.65e-01 | 8.00e-02 |
| DEPOLYMERISATION OF THE NUCLEAR LAMINA | 13 | 9.79e-02 | 2.65e-01 | 2.72e-01 |
| SIGNALING BY HEDGEHOG | 141 | 5.54e-08 | 2.65e-01 | 3.46e-06 |
| ROS AND RNS PRODUCTION IN PHAGOCYTES | 28 | 1.53e-02 | 2.65e-01 | 7.58e-02 |
| G ALPHA Z SIGNALLING EVENTS | 45 | 2.20e-03 | 2.64e-01 | 1.97e-02 |
| G1 S SPECIFIC TRANSCRIPTION | 26 | 2.08e-02 | 2.62e-01 | 9.24e-02 |
| NUCLEOTIDE SALVAGE | 21 | 3.78e-02 | 2.62e-01 | 1.40e-01 |
| TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 | 15 | 7.92e-02 | 2.62e-01 | 2.34e-01 |
| FORMATION OF APOPTOSOME | 10 | 1.52e-01 | 2.62e-01 | 3.69e-01 |
| TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE | 63 | 3.31e-04 | 2.62e-01 | 4.76e-03 |
| PENTOSE PHOSPHATE PATHWAY | 13 | 1.03e-01 | 2.61e-01 | 2.84e-01 |
| NEUROTOXICITY OF CLOSTRIDIUM TOXINS | 10 | 1.53e-01 | 2.61e-01 | 3.70e-01 |
| SEROTONIN RECEPTORS | 10 | 1.54e-01 | 2.60e-01 | 3.71e-01 |
| PKA ACTIVATION IN GLUCAGON SIGNALLING | 16 | 7.18e-02 | 2.60e-01 | 2.19e-01 |
| LAMININ INTERACTIONS | 29 | 1.56e-02 | -2.60e-01 | 7.67e-02 |
| HEDGEHOG OFF STATE | 106 | 3.96e-06 | 2.59e-01 | 1.41e-04 |
| ERKS ARE INACTIVATED | 13 | 1.06e-01 | 2.59e-01 | 2.86e-01 |
| UPTAKE AND ACTIONS OF BACTERIAL TOXINS | 28 | 1.81e-02 | 2.58e-01 | 8.34e-02 |
| DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE | 20 | 4.62e-02 | 2.58e-01 | 1.63e-01 |
| TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX | 18 | 5.96e-02 | 2.56e-01 | 1.92e-01 |
| ACTIVATION OF RAC1 | 13 | 1.10e-01 | 2.56e-01 | 2.93e-01 |
| TRANSFERRIN ENDOCYTOSIS AND RECYCLING | 26 | 2.39e-02 | 2.56e-01 | 1.01e-01 |
| FGFR2 LIGAND BINDING AND ACTIVATION | 12 | 1.25e-01 | -2.56e-01 | 3.20e-01 |
| GLYCOSAMINOGLYCAN METABOLISM | 113 | 2.77e-06 | 2.55e-01 | 1.12e-04 |
| UPTAKE AND FUNCTION OF ANTHRAX TOXINS | 11 | 1.45e-01 | 2.54e-01 | 3.59e-01 |
| GLUCAGON SIGNALING IN METABOLIC REGULATION | 30 | 1.64e-02 | 2.53e-01 | 7.89e-02 |
| PROCESSING AND ACTIVATION OF SUMO | 10 | 1.66e-01 | 2.53e-01 | 3.88e-01 |
| RHO GTPASES ACTIVATE WASPS AND WAVES | 36 | 8.70e-03 | 2.53e-01 | 5.13e-02 |
| LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME | 13 | 1.15e-01 | -2.53e-01 | 3.00e-01 |
| CHONDROITIN SULFATE BIOSYNTHESIS | 18 | 6.42e-02 | 2.52e-01 | 2.02e-01 |
| WNT5A DEPENDENT INTERNALIZATION OF FZD4 | 15 | 9.13e-02 | 2.52e-01 | 2.60e-01 |
| MITOPHAGY | 29 | 1.93e-02 | 2.51e-01 | 8.72e-02 |
| REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION | 10 | 1.69e-01 | -2.51e-01 | 3.93e-01 |
| PROTEIN FOLDING | 90 | 4.10e-05 | 2.50e-01 | 9.11e-04 |
| O LINKED GLYCOSYLATION OF MUCINS | 40 | 6.62e-03 | 2.48e-01 | 4.30e-02 |
| TELOMERE C STRAND SYNTHESIS INITIATION | 13 | 1.24e-01 | 2.46e-01 | 3.18e-01 |
| METABOLISM OF POLYAMINES | 57 | 1.34e-03 | 2.46e-01 | 1.38e-02 |
| CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING | 28 | 2.51e-02 | 2.45e-01 | 1.05e-01 |
| RHOBTB2 GTPASE CYCLE | 23 | 4.23e-02 | 2.45e-01 | 1.53e-01 |
| REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | 92 | 5.22e-05 | 2.44e-01 | 1.10e-03 |
| INTERACTION BETWEEN L1 AND ANKYRINS | 27 | 2.84e-02 | -2.44e-01 | 1.14e-01 |
| HEDGEHOG LIGAND BIOGENESIS | 61 | 1.02e-03 | 2.43e-01 | 1.11e-02 |
| PROLACTIN RECEPTOR SIGNALING | 11 | 1.63e-01 | 2.43e-01 | 3.83e-01 |
| ATTENUATION PHASE | 23 | 4.41e-02 | 2.43e-01 | 1.58e-01 |
| PROTEIN LOCALIZATION | 158 | 1.53e-07 | 2.42e-01 | 8.60e-06 |
| ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS | 10 | 1.87e-01 | 2.41e-01 | 4.19e-01 |
| TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN | 12 | 1.50e-01 | 2.40e-01 | 3.67e-01 |
| REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS | 12 | 1.50e-01 | 2.40e-01 | 3.68e-01 |
| TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES | 11 | 1.69e-01 | -2.39e-01 | 3.93e-01 |
| NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS | 21 | 5.79e-02 | 2.39e-01 | 1.90e-01 |
| GABA RECEPTOR ACTIVATION | 55 | 2.25e-03 | 2.38e-01 | 1.99e-02 |
| PLATELET ADHESION TO EXPOSED COLLAGEN | 13 | 1.37e-01 | -2.38e-01 | 3.43e-01 |
| SIGNALING BY NODAL | 15 | 1.10e-01 | -2.38e-01 | 2.93e-01 |
| POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION | 26 | 3.57e-02 | 2.38e-01 | 1.34e-01 |
| METABOLISM OF CARBOHYDRATES | 260 | 4.24e-11 | 2.38e-01 | 8.33e-09 |
| O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS | 35 | 1.53e-02 | -2.37e-01 | 7.58e-02 |
| G0 AND EARLY G1 | 25 | 4.06e-02 | 2.37e-01 | 1.48e-01 |
| TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN | 20 | 6.87e-02 | 2.35e-01 | 2.13e-01 |
| TRIGLYCERIDE CATABOLISM | 14 | 1.29e-01 | 2.34e-01 | 3.28e-01 |
| REGULATION OF IFNG SIGNALING | 13 | 1.44e-01 | 2.34e-01 | 3.58e-01 |
| ABC TRANSPORTER DISORDERS | 70 | 7.34e-04 | 2.33e-01 | 8.73e-03 |
| CHEMOKINE RECEPTORS BIND CHEMOKINES | 17 | 9.59e-02 | -2.33e-01 | 2.69e-01 |
| DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS | 11 | 1.81e-01 | -2.33e-01 | 4.08e-01 |
| REGULATION OF HMOX1 EXPRESSION AND ACTIVITY | 63 | 1.42e-03 | 2.32e-01 | 1.45e-02 |
| UNFOLDED PROTEIN RESPONSE UPR | 85 | 2.14e-04 | 2.32e-01 | 3.45e-03 |
| PLASMA LIPOPROTEIN CLEARANCE | 28 | 3.40e-02 | 2.32e-01 | 1.31e-01 |
| TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA | 16 | 1.11e-01 | -2.30e-01 | 2.93e-01 |
| GLUTATHIONE SYNTHESIS AND RECYCLING | 11 | 1.88e-01 | 2.29e-01 | 4.19e-01 |
| THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | 28 | 3.56e-02 | 2.29e-01 | 1.34e-01 |
| SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX | 12 | 1.70e-01 | 2.29e-01 | 3.93e-01 |
| CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY | 84 | 3.03e-04 | 2.28e-01 | 4.52e-03 |
| CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | 48 | 6.47e-03 | 2.27e-01 | 4.23e-02 |
| EXTRA NUCLEAR ESTROGEN SIGNALING | 68 | 1.20e-03 | 2.27e-01 | 1.27e-02 |
| ATF6 ATF6 ALPHA ACTIVATES CHAPERONES | 12 | 1.73e-01 | 2.27e-01 | 3.98e-01 |
| CLASS B 2 SECRETIN FAMILY RECEPTORS | 73 | 8.07e-04 | 2.27e-01 | 9.14e-03 |
| ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | 30 | 3.22e-02 | 2.26e-01 | 1.26e-01 |
| REGULATION OF TP53 EXPRESSION AND DEGRADATION | 34 | 2.26e-02 | 2.26e-01 | 9.77e-02 |
| INTEGRATION OF ENERGY METABOLISM | 100 | 9.93e-05 | 2.25e-01 | 1.89e-03 |
| METABOLISM OF NUCLEOTIDES | 92 | 1.97e-04 | 2.25e-01 | 3.23e-03 |
| PLATELET SENSITIZATION BY LDL | 15 | 1.34e-01 | 2.23e-01 | 3.37e-01 |
| NEGATIVE REGULATION OF FGFR3 SIGNALING | 24 | 5.83e-02 | 2.23e-01 | 1.90e-01 |
| A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | 26 | 4.94e-02 | 2.23e-01 | 1.70e-01 |
| REGULATION OF RUNX1 EXPRESSION AND ACTIVITY | 17 | 1.13e-01 | -2.22e-01 | 2.97e-01 |
| SYNTHESIS OF PA | 29 | 3.93e-02 | 2.21e-01 | 1.44e-01 |
| CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | 46 | 9.62e-03 | 2.21e-01 | 5.43e-02 |
| SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | 18 | 1.05e-01 | 2.20e-01 | 2.85e-01 |
| TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS | 18 | 1.07e-01 | 2.20e-01 | 2.87e-01 |
| HEPARAN SULFATE HEPARIN HS GAG METABOLISM | 52 | 6.26e-03 | 2.19e-01 | 4.17e-02 |
| TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | 13 | 1.72e-01 | -2.19e-01 | 3.96e-01 |
| ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS | 36 | 2.33e-02 | 2.18e-01 | 1.00e-01 |
| SCAVENGING OF HEME FROM PLASMA | 12 | 1.91e-01 | -2.18e-01 | 4.24e-01 |
| SIGNAL TRANSDUCTION BY L1 | 21 | 8.47e-02 | 2.17e-01 | 2.47e-01 |
| HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE | 41 | 1.61e-02 | -2.17e-01 | 7.83e-02 |
| FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES | 15 | 1.45e-01 | -2.17e-01 | 3.59e-01 |
| RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY | 15 | 1.48e-01 | 2.16e-01 | 3.64e-01 |
| DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS | 17 | 1.23e-01 | 2.16e-01 | 3.17e-01 |
| VEGFR2 MEDIATED CELL PROLIFERATION | 19 | 1.04e-01 | 2.15e-01 | 2.84e-01 |
| PYRUVATE METABOLISM | 27 | 5.33e-02 | 2.15e-01 | 1.78e-01 |
| INTERLEUKIN 10 SIGNALING | 19 | 1.05e-01 | -2.15e-01 | 2.85e-01 |
| SARS COV 2 INFECTION | 65 | 2.77e-03 | 2.15e-01 | 2.30e-02 |
| PROTEIN UBIQUITINATION | 70 | 1.93e-03 | 2.14e-01 | 1.77e-02 |
| MITOCHONDRIAL TRNA AMINOACYLATION | 21 | 8.93e-02 | 2.14e-01 | 2.56e-01 |
| SIALIC ACID METABOLISM | 32 | 3.63e-02 | 2.14e-01 | 1.35e-01 |
| PI 3K CASCADE FGFR2 | 17 | 1.27e-01 | -2.14e-01 | 3.24e-01 |
| STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS | 10 | 2.43e-01 | -2.13e-01 | 4.84e-01 |
| NEGATIVE REGULATION OF FGFR4 SIGNALING | 24 | 7.14e-02 | 2.13e-01 | 2.19e-01 |
| REGULATION OF PTEN STABILITY AND ACTIVITY | 66 | 2.87e-03 | 2.12e-01 | 2.35e-02 |
| DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE | 26 | 6.20e-02 | 2.11e-01 | 1.98e-01 |
| GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION | 39 | 2.26e-02 | 2.11e-01 | 9.77e-02 |
| HS GAG BIOSYNTHESIS | 30 | 4.56e-02 | 2.11e-01 | 1.61e-01 |
| HDR THROUGH HOMOLOGOUS RECOMBINATION HRR | 64 | 3.74e-03 | -2.10e-01 | 2.80e-02 |
| REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | 15 | 1.60e-01 | 2.09e-01 | 3.79e-01 |
| MTORC1 MEDIATED SIGNALLING | 24 | 7.66e-02 | 2.09e-01 | 2.30e-01 |
| HDACS DEACETYLATE HISTONES | 50 | 1.09e-02 | -2.08e-01 | 6.01e-02 |
| CGMP EFFECTS | 15 | 1.64e-01 | -2.07e-01 | 3.85e-01 |
| REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS | 15 | 1.66e-01 | -2.07e-01 | 3.87e-01 |
| DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | 78 | 1.60e-03 | 2.07e-01 | 1.57e-02 |
| FERTILIZATION | 13 | 1.98e-01 | -2.06e-01 | 4.31e-01 |
| INTEGRIN CELL SURFACE INTERACTIONS | 75 | 2.01e-03 | -2.06e-01 | 1.84e-02 |
| ACYL CHAIN REMODELLING OF PG | 10 | 2.59e-01 | 2.06e-01 | 5.02e-01 |
| FCERI MEDIATED NF KB ACTIVATION | 76 | 1.89e-03 | 2.06e-01 | 1.77e-02 |
| G BETA GAMMA SIGNALLING THROUGH CDC42 | 19 | 1.20e-01 | 2.06e-01 | 3.10e-01 |
| SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS | 15 | 1.67e-01 | 2.06e-01 | 3.90e-01 |
| INTRA GOLGI TRAFFIC | 43 | 1.96e-02 | 2.06e-01 | 8.81e-02 |
| TRANS GOLGI NETWORK VESICLE BUDDING | 70 | 2.94e-03 | 2.06e-01 | 2.39e-02 |
| PROCESSING OF SMDT1 | 16 | 1.54e-01 | 2.06e-01 | 3.71e-01 |
| BETA CATENIN PHOSPHORYLATION CASCADE | 16 | 1.55e-01 | 2.05e-01 | 3.71e-01 |
| SYNTHESIS OF PC | 26 | 7.08e-02 | 2.05e-01 | 2.18e-01 |
| GLYCEROPHOSPHOLIPID BIOSYNTHESIS | 109 | 2.30e-04 | 2.04e-01 | 3.66e-03 |
| AMINE LIGAND BINDING RECEPTORS | 29 | 5.70e-02 | 2.04e-01 | 1.88e-01 |
| SPHINGOLIPID DE NOVO BIOSYNTHESIS | 42 | 2.24e-02 | 2.04e-01 | 9.73e-02 |
| GABA B RECEPTOR ACTIVATION | 40 | 2.62e-02 | 2.03e-01 | 1.07e-01 |
| NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX | 32 | 4.68e-02 | -2.03e-01 | 1.64e-01 |
| REGULATION OF INSULIN SECRETION | 72 | 2.98e-03 | 2.02e-01 | 2.40e-02 |
| MTOR SIGNALLING | 40 | 2.69e-02 | 2.02e-01 | 1.09e-01 |
| VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS | 37 | 3.35e-02 | 2.02e-01 | 1.30e-01 |
| BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA | 16 | 1.63e-01 | -2.01e-01 | 3.83e-01 |
| LATE ENDOSOMAL MICROAUTOPHAGY | 32 | 4.88e-02 | 2.01e-01 | 1.69e-01 |
| RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK | 48 | 1.61e-02 | 2.01e-01 | 7.83e-02 |
| KINESINS | 47 | 1.77e-02 | 2.00e-01 | 8.20e-02 |
| ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS | 84 | 1.55e-03 | 2.00e-01 | 1.53e-02 |
| PROLONGED ERK ACTIVATION EVENTS | 13 | 2.13e-01 | 1.99e-01 | 4.51e-01 |
| NCAM1 INTERACTIONS | 42 | 2.54e-02 | -1.99e-01 | 1.05e-01 |
| DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS | 18 | 1.44e-01 | 1.99e-01 | 3.58e-01 |
| ERYTHROPOIETIN ACTIVATES RAS | 13 | 2.14e-01 | 1.99e-01 | 4.51e-01 |
| MEMBRANE TRAFFICKING | 582 | 2.90e-16 | 1.99e-01 | 1.14e-13 |
| PEPTIDE HORMONE METABOLISM | 60 | 7.82e-03 | 1.99e-01 | 4.80e-02 |
| SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | 14 | 1.98e-01 | 1.99e-01 | 4.32e-01 |
| CELLULAR RESPONSE TO HEAT STRESS | 94 | 9.54e-04 | 1.97e-01 | 1.05e-02 |
| IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | 51 | 1.51e-02 | -1.97e-01 | 7.55e-02 |
| ACTIVATION OF BH3 ONLY PROTEINS | 30 | 6.24e-02 | 1.97e-01 | 1.99e-01 |
| DEGRADATION OF GLI1 BY THE PROTEASOME | 57 | 1.03e-02 | 1.96e-01 | 5.74e-02 |
| HDR THROUGH SINGLE STRAND ANNEALING SSA | 37 | 3.91e-02 | -1.96e-01 | 1.44e-01 |
| THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | 23 | 1.04e-01 | 1.96e-01 | 2.84e-01 |
| DISEASES OF DNA REPAIR | 11 | 2.62e-01 | 1.95e-01 | 5.03e-01 |
| NEGATIVE REGULATION OF NOTCH4 SIGNALING | 54 | 1.31e-02 | 1.95e-01 | 6.79e-02 |
| REGULATION OF KIT SIGNALING | 16 | 1.77e-01 | 1.95e-01 | 4.04e-01 |
| CLATHRIN MEDIATED ENDOCYTOSIS | 134 | 1.01e-04 | 1.95e-01 | 1.89e-03 |
| NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | 20 | 1.32e-01 | -1.95e-01 | 3.33e-01 |
| STABILIZATION OF P53 | 54 | 1.36e-02 | 1.94e-01 | 6.92e-02 |
| CA DEPENDENT EVENTS | 36 | 4.38e-02 | 1.94e-01 | 1.57e-01 |
| CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT | 20 | 1.33e-01 | 1.94e-01 | 3.35e-01 |
| CD28 CO STIMULATION | 31 | 6.20e-02 | 1.94e-01 | 1.98e-01 |
| NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION | 182 | 6.77e-06 | 1.94e-01 | 2.22e-04 |
| RAB GEFS EXCHANGE GTP FOR GDP ON RABS | 88 | 1.72e-03 | 1.93e-01 | 1.64e-02 |
| ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK | 28 | 7.71e-02 | 1.93e-01 | 2.30e-01 |
| MITOTIC METAPHASE AND ANAPHASE | 207 | 1.79e-06 | 1.93e-01 | 8.42e-05 |
| FATTY ACID METABOLISM | 146 | 6.10e-05 | 1.92e-01 | 1.21e-03 |
| B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION | 51 | 1.76e-02 | -1.92e-01 | 8.19e-02 |
| REGULATION OF RAS BY GAPS | 66 | 7.17e-03 | 1.91e-01 | 4.57e-02 |
| REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE | 75 | 4.23e-03 | 1.91e-01 | 3.08e-02 |
| NEUTROPHIL DEGRANULATION | 386 | 1.25e-10 | 1.91e-01 | 1.48e-08 |
| PINK1 PRKN MEDIATED MITOPHAGY | 22 | 1.21e-01 | 1.91e-01 | 3.11e-01 |
| APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS | 81 | 3.11e-03 | 1.90e-01 | 2.49e-02 |
| E2F MEDIATED REGULATION OF DNA REPLICATION | 19 | 1.51e-01 | 1.90e-01 | 3.69e-01 |
| NEDDYLATION | 219 | 1.33e-06 | 1.90e-01 | 6.51e-05 |
| ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS | 10 | 2.99e-01 | -1.90e-01 | 5.45e-01 |
| METHYLATION | 11 | 2.77e-01 | 1.89e-01 | 5.19e-01 |
| VXPX CARGO TARGETING TO CILIUM | 19 | 1.53e-01 | 1.89e-01 | 3.70e-01 |
| HEME SIGNALING | 46 | 2.63e-02 | -1.89e-01 | 1.07e-01 |
| ADENYLATE CYCLASE ACTIVATING PATHWAY | 10 | 3.03e-01 | 1.88e-01 | 5.50e-01 |
| FC EPSILON RECEPTOR FCERI SIGNALING | 123 | 3.19e-04 | 1.88e-01 | 4.63e-03 |
| DSCAM INTERACTIONS | 11 | 2.82e-01 | -1.87e-01 | 5.23e-01 |
| DISEASES OF CARBOHYDRATE METABOLISM | 29 | 8.12e-02 | 1.87e-01 | 2.38e-01 |
| SYNTHESIS OF PE | 13 | 2.44e-01 | 1.87e-01 | 4.84e-01 |
| TBC RABGAPS | 43 | 3.43e-02 | 1.87e-01 | 1.31e-01 |
| AMINO ACIDS REGULATE MTORC1 | 51 | 2.15e-02 | 1.86e-01 | 9.45e-02 |
| CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION | 22 | 1.32e-01 | 1.86e-01 | 3.33e-01 |
| VESICLE MEDIATED TRANSPORT | 615 | 4.77e-15 | 1.85e-01 | 1.40e-12 |
| NUCLEOBASE CATABOLISM | 31 | 7.40e-02 | 1.85e-01 | 2.23e-01 |
| SCF SKP2 MEDIATED DEGRADATION OF P27 P21 | 59 | 1.39e-02 | 1.85e-01 | 7.04e-02 |
| NEGATIVE REGULATION OF MET ACTIVITY | 20 | 1.52e-01 | 1.85e-01 | 3.69e-01 |
| RHOF GTPASE CYCLE | 41 | 4.10e-02 | 1.84e-01 | 1.49e-01 |
| SYNTHESIS OF BILE ACIDS AND BILE SALTS | 23 | 1.27e-01 | 1.84e-01 | 3.24e-01 |
| RESOLUTION OF SISTER CHROMATID COHESION | 102 | 1.37e-03 | 1.83e-01 | 1.40e-02 |
| REGULATION OF RUNX3 EXPRESSION AND ACTIVITY | 53 | 2.09e-02 | 1.83e-01 | 9.25e-02 |
| FCGR3A MEDIATED IL10 SYNTHESIS | 32 | 7.31e-02 | 1.83e-01 | 2.21e-01 |
| PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 | 12 | 2.74e-01 | -1.83e-01 | 5.15e-01 |
| APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | 70 | 8.31e-03 | 1.82e-01 | 4.97e-02 |
| GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | 18 | 1.81e-01 | 1.82e-01 | 4.08e-01 |
| METAL ION SLC TRANSPORTERS | 25 | 1.16e-01 | 1.82e-01 | 3.02e-01 |
| INTERFERON SIGNALING | 162 | 6.94e-05 | -1.81e-01 | 1.34e-03 |
| DEFECTS IN COBALAMIN B12 METABOLISM | 13 | 2.58e-01 | 1.81e-01 | 5.02e-01 |
| COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM | 14 | 2.42e-01 | 1.81e-01 | 4.82e-01 |
| RORA ACTIVATES GENE EXPRESSION | 18 | 1.84e-01 | -1.81e-01 | 4.15e-01 |
| HEDGEHOG ON STATE | 82 | 4.81e-03 | 1.80e-01 | 3.40e-02 |
| METABOLISM OF FAT SOLUBLE VITAMINS | 32 | 7.80e-02 | 1.80e-01 | 2.32e-01 |
| CRMPS IN SEMA3A SIGNALING | 16 | 2.13e-01 | -1.80e-01 | 4.51e-01 |
| PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | 17 | 2.01e-01 | 1.79e-01 | 4.36e-01 |
| CILIUM ASSEMBLY | 192 | 1.93e-05 | 1.79e-01 | 5.16e-04 |
| CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION | 11 | 3.04e-01 | 1.79e-01 | 5.50e-01 |
| MITOCHONDRIAL FATTY ACID BETA OXIDATION | 34 | 7.12e-02 | 1.79e-01 | 2.19e-01 |
| REDUCTION OF CYTOSOLIC CA LEVELS | 12 | 2.87e-01 | -1.78e-01 | 5.28e-01 |
| RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | 107 | 1.54e-03 | 1.77e-01 | 1.53e-02 |
| GPCR LIGAND BINDING | 271 | 5.43e-07 | 1.77e-01 | 2.91e-05 |
| ASSEMBLY OF THE HIV VIRION | 16 | 2.21e-01 | 1.77e-01 | 4.57e-01 |
| LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS | 20 | 1.72e-01 | 1.76e-01 | 3.96e-01 |
| BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION | 26 | 1.21e-01 | -1.76e-01 | 3.11e-01 |
| EPHB MEDIATED FORWARD SIGNALING | 42 | 4.92e-02 | 1.75e-01 | 1.69e-01 |
| COMPLEX I BIOGENESIS | 56 | 2.33e-02 | -1.75e-01 | 1.00e-01 |
| COLLAGEN CHAIN TRIMERIZATION | 41 | 5.24e-02 | -1.75e-01 | 1.76e-01 |
| FCERI MEDIATED MAPK ACTIVATION | 28 | 1.10e-01 | 1.74e-01 | 2.93e-01 |
| RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR | 20 | 1.77e-01 | 1.74e-01 | 4.04e-01 |
| G ALPHA Q SIGNALLING EVENTS | 155 | 1.82e-04 | 1.74e-01 | 3.03e-03 |
| CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS | 94 | 3.55e-03 | 1.74e-01 | 2.73e-02 |
| EGFR DOWNREGULATION | 28 | 1.11e-01 | 1.74e-01 | 2.94e-01 |
| PI 3K CASCADE FGFR1 | 16 | 2.29e-01 | -1.74e-01 | 4.69e-01 |
| TRANSMISSION ACROSS CHEMICAL SYNAPSES | 243 | 3.18e-06 | 1.74e-01 | 1.25e-04 |
| STRIATED MUSCLE CONTRACTION | 27 | 1.18e-01 | -1.74e-01 | 3.07e-01 |
| ABC FAMILY PROTEINS MEDIATED TRANSPORT | 95 | 3.55e-03 | 1.73e-01 | 2.73e-02 |
| SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | 62 | 1.84e-02 | 1.73e-01 | 8.40e-02 |
| SARS COV 1 INFECTION | 48 | 3.83e-02 | 1.73e-01 | 1.42e-01 |
| PCP CE PATHWAY | 89 | 4.98e-03 | 1.72e-01 | 3.45e-02 |
| SIGNALING BY FGFR3 | 34 | 8.23e-02 | 1.72e-01 | 2.41e-01 |
| ACYL CHAIN REMODELLING OF PC | 17 | 2.21e-01 | 1.72e-01 | 4.57e-01 |
| SEPARATION OF SISTER CHROMATIDS | 166 | 1.41e-04 | 1.71e-01 | 2.55e-03 |
| PHOSPHOLIPID METABOLISM | 188 | 5.24e-05 | 1.71e-01 | 1.10e-03 |
| MITOTIC G1 PHASE AND G1 S TRANSITION | 142 | 4.35e-04 | 1.71e-01 | 5.89e-03 |
| AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA | 53 | 3.12e-02 | 1.71e-01 | 1.24e-01 |
| BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | 76 | 9.97e-03 | 1.71e-01 | 5.58e-02 |
| DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | 23 | 1.58e-01 | -1.70e-01 | 3.75e-01 |
| G1 S DNA DAMAGE CHECKPOINTS | 65 | 1.78e-02 | 1.70e-01 | 8.20e-02 |
| ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION | 27 | 1.30e-01 | 1.68e-01 | 3.29e-01 |
| TERMINATION OF TRANSLESION DNA SYNTHESIS | 32 | 9.97e-02 | -1.68e-01 | 2.76e-01 |
| TRANSCRIPTIONAL REGULATION BY MECP2 | 59 | 2.63e-02 | -1.67e-01 | 1.07e-01 |
| TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS | 68 | 1.74e-02 | 1.67e-01 | 8.13e-02 |
| ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 | 24 | 1.57e-01 | 1.67e-01 | 3.75e-01 |
| GLUCOSE METABOLISM | 81 | 9.52e-03 | 1.67e-01 | 5.43e-02 |
| ANCHORING FIBRIL FORMATION | 14 | 2.80e-01 | -1.67e-01 | 5.22e-01 |
| TIGHT JUNCTION INTERACTIONS | 16 | 2.51e-01 | 1.66e-01 | 4.93e-01 |
| NEGATIVE REGULATION OF MAPK PATHWAY | 42 | 6.36e-02 | 1.65e-01 | 2.01e-01 |
| BLOOD GROUP SYSTEMS BIOSYNTHESIS | 15 | 2.67e-01 | 1.65e-01 | 5.07e-01 |
| SIGNALING BY FLT3 FUSION PROTEINS | 19 | 2.13e-01 | -1.65e-01 | 4.51e-01 |
| SIGNALING BY FGFR4 | 34 | 9.67e-02 | 1.65e-01 | 2.70e-01 |
| METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION | 15 | 2.70e-01 | 1.65e-01 | 5.11e-01 |
| PRC2 METHYLATES HISTONES AND DNA | 33 | 1.02e-01 | -1.65e-01 | 2.80e-01 |
| POST TRANSLATIONAL PROTEIN MODIFICATION | 1230 | 4.84e-22 | 1.65e-01 | 5.70e-19 |
| GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION | 31 | 1.14e-01 | 1.64e-01 | 2.98e-01 |
| CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND | 13 | 3.06e-01 | -1.64e-01 | 5.50e-01 |
| INTERLEUKIN 12 FAMILY SIGNALING | 43 | 6.29e-02 | 1.64e-01 | 2.00e-01 |
| GOLGI ASSOCIATED VESICLE BIOGENESIS | 55 | 3.56e-02 | 1.64e-01 | 1.34e-01 |
| JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | 22 | 1.84e-01 | 1.64e-01 | 4.14e-01 |
| INTERLEUKIN 12 SIGNALING | 37 | 8.59e-02 | 1.63e-01 | 2.49e-01 |
| TERMINATION OF O GLYCAN BIOSYNTHESIS | 10 | 3.72e-01 | 1.63e-01 | 6.07e-01 |
| PLATELET ACTIVATION SIGNALING AND AGGREGATION | 224 | 2.81e-05 | 1.63e-01 | 7.05e-04 |
| OPIOID SIGNALLING | 87 | 8.99e-03 | 1.62e-01 | 5.24e-02 |
| ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 | 25 | 1.61e-01 | -1.62e-01 | 3.80e-01 |
| ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY | 10 | 3.78e-01 | 1.61e-01 | 6.07e-01 |
| COMMON PATHWAY OF FIBRIN CLOT FORMATION | 11 | 3.55e-01 | 1.61e-01 | 5.98e-01 |
| CLASS A 1 RHODOPSIN LIKE RECEPTORS | 187 | 1.58e-04 | 1.60e-01 | 2.82e-03 |
| DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX | 82 | 1.23e-02 | 1.60e-01 | 6.51e-02 |
| ORC1 REMOVAL FROM CHROMATIN | 67 | 2.35e-02 | 1.60e-01 | 1.00e-01 |
| REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM | 11 | 3.60e-01 | 1.60e-01 | 6.00e-01 |
| PRE NOTCH PROCESSING IN GOLGI | 18 | 2.42e-01 | 1.59e-01 | 4.82e-01 |
| MET ACTIVATES RAP1 AND RAC1 | 10 | 3.83e-01 | 1.59e-01 | 6.09e-01 |
| RHO GTPASES ACTIVATE FORMINS | 119 | 2.72e-03 | 1.59e-01 | 2.29e-02 |
| FRS MEDIATED FGFR3 SIGNALING | 15 | 2.86e-01 | 1.59e-01 | 5.26e-01 |
| PIWI INTERACTING RNA PIRNA BIOGENESIS | 19 | 2.30e-01 | -1.59e-01 | 4.71e-01 |
| MITOCHONDRIAL PROTEIN IMPORT | 63 | 2.94e-02 | 1.59e-01 | 1.17e-01 |
| MUCOPOLYSACCHARIDOSES | 11 | 3.63e-01 | 1.58e-01 | 6.02e-01 |
| INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | 19 | 2.32e-01 | 1.58e-01 | 4.72e-01 |
| HOST INTERACTIONS OF HIV FACTORS | 125 | 2.24e-03 | 1.58e-01 | 1.99e-02 |
| EPH EPHRIN SIGNALING | 92 | 8.92e-03 | 1.58e-01 | 5.23e-02 |
| DEFECTIVE EXT2 CAUSES EXOSTOSES 2 | 14 | 3.08e-01 | 1.57e-01 | 5.52e-01 |
| E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS | 51 | 5.21e-02 | 1.57e-01 | 1.76e-01 |
| SIGNALING BY HIPPO | 20 | 2.24e-01 | 1.57e-01 | 4.61e-01 |
| ENOS ACTIVATION | 11 | 3.68e-01 | 1.57e-01 | 6.06e-01 |
| SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE | 86 | 1.20e-02 | 1.57e-01 | 6.42e-02 |
| TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS | 44 | 7.24e-02 | 1.57e-01 | 2.20e-01 |
| DNA METHYLATION | 24 | 1.85e-01 | -1.56e-01 | 4.15e-01 |
| TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE | 39 | 9.14e-02 | -1.56e-01 | 2.60e-01 |
| PARASITE INFECTION | 54 | 4.74e-02 | 1.56e-01 | 1.66e-01 |
| CHAPERONE MEDIATED AUTOPHAGY | 21 | 2.17e-01 | 1.56e-01 | 4.53e-01 |
| SIGNALING BY THE B CELL RECEPTOR BCR | 103 | 6.34e-03 | 1.56e-01 | 4.20e-02 |
| DNA REPLICATION PRE INITIATION | 80 | 1.66e-02 | 1.55e-01 | 7.90e-02 |
| DEGRADATION OF AXIN | 53 | 5.12e-02 | 1.55e-01 | 1.74e-01 |
| FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS | 81 | 1.60e-02 | 1.55e-01 | 7.83e-02 |
| SHC1 EVENTS IN EGFR SIGNALING | 11 | 3.74e-01 | 1.55e-01 | 6.07e-01 |
| DEGRADATION OF DVL | 55 | 4.81e-02 | 1.54e-01 | 1.67e-01 |
| PHASE 2 PLATEAU PHASE | 10 | 3.99e-01 | -1.54e-01 | 6.24e-01 |
| TCR SIGNALING | 101 | 7.60e-03 | 1.54e-01 | 4.77e-02 |
| CELL EXTRACELLULAR MATRIX INTERACTIONS | 18 | 2.59e-01 | 1.54e-01 | 5.02e-01 |
| COHESIN LOADING ONTO CHROMATIN | 10 | 4.00e-01 | -1.54e-01 | 6.24e-01 |
| ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS | 22 | 2.12e-01 | 1.54e-01 | 4.51e-01 |
| INOSITOL PHOSPHATE METABOLISM | 46 | 7.17e-02 | 1.54e-01 | 2.19e-01 |
| EUKARYOTIC TRANSLATION ELONGATION | 88 | 1.29e-02 | -1.53e-01 | 6.77e-02 |
| VITAMIN B5 PANTOTHENATE METABOLISM | 15 | 3.04e-01 | 1.53e-01 | 5.50e-01 |
| RAB REGULATION OF TRAFFICKING | 119 | 3.90e-03 | 1.53e-01 | 2.91e-02 |
| TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY | 12 | 3.58e-01 | -1.53e-01 | 6.00e-01 |
| GROWTH HORMONE RECEPTOR SIGNALING | 20 | 2.37e-01 | 1.53e-01 | 4.78e-01 |
| METABOLISM OF LIPIDS | 619 | 1.04e-10 | 1.53e-01 | 1.48e-08 |
| THE NLRP3 INFLAMMASOME | 15 | 3.08e-01 | -1.52e-01 | 5.52e-01 |
| G ALPHA I SIGNALLING EVENTS | 207 | 1.74e-04 | 1.52e-01 | 2.93e-03 |
| G PROTEIN MEDIATED EVENTS | 52 | 5.96e-02 | 1.51e-01 | 1.92e-01 |
| C TYPE LECTIN RECEPTORS CLRS | 112 | 5.78e-03 | 1.51e-01 | 3.89e-02 |
| TRAF6 MEDIATED IRF7 ACTIVATION | 15 | 3.13e-01 | -1.50e-01 | 5.57e-01 |
| SYNAPTIC ADHESION LIKE MOLECULES | 21 | 2.33e-01 | 1.50e-01 | 4.73e-01 |
| MET ACTIVATES PTK2 SIGNALING | 29 | 1.62e-01 | -1.50e-01 | 3.82e-01 |
| NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 2.84e-01 | 1.50e-01 | 5.25e-01 |
| GP1B IX V ACTIVATION SIGNALLING | 11 | 3.90e-01 | -1.50e-01 | 6.16e-01 |
| AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | 25 | 1.97e-01 | 1.49e-01 | 4.31e-01 |
| TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES | 45 | 8.49e-02 | 1.48e-01 | 2.47e-01 |
| HYALURONAN METABOLISM | 15 | 3.20e-01 | 1.48e-01 | 5.64e-01 |
| INTERLEUKIN 15 SIGNALING | 12 | 3.74e-01 | -1.48e-01 | 6.07e-01 |
| CLEC7A DECTIN 1 SIGNALING | 94 | 1.33e-02 | 1.48e-01 | 6.82e-02 |
| DEADENYLATION OF MRNA | 25 | 2.02e-01 | 1.48e-01 | 4.36e-01 |
| L1CAM INTERACTIONS | 108 | 8.16e-03 | 1.47e-01 | 4.91e-02 |
| AQUAPORIN MEDIATED TRANSPORT | 41 | 1.04e-01 | 1.47e-01 | 2.84e-01 |
| CELLULAR RESPONSE TO HYPOXIA | 72 | 3.17e-02 | 1.46e-01 | 1.25e-01 |
| DAG AND IP3 SIGNALING | 40 | 1.13e-01 | 1.45e-01 | 2.97e-01 |
| G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | 24 | 2.19e-01 | 1.45e-01 | 4.57e-01 |
| FGFR1 LIGAND BINDING AND ACTIVATION | 10 | 4.28e-01 | -1.45e-01 | 6.47e-01 |
| CYTOCHROME C MEDIATED APOPTOTIC RESPONSE | 12 | 3.87e-01 | 1.44e-01 | 6.12e-01 |
| ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS | 10 | 4.32e-01 | 1.44e-01 | 6.49e-01 |
| HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | 10 | 4.32e-01 | 1.44e-01 | 6.49e-01 |
| RHO GTPASES ACTIVATE NADPH OXIDASES | 20 | 2.67e-01 | 1.43e-01 | 5.07e-01 |
| INTRINSIC PATHWAY FOR APOPTOSIS | 52 | 7.42e-02 | 1.43e-01 | 2.23e-01 |
| SIGNALLING TO ERKS | 33 | 1.55e-01 | 1.43e-01 | 3.71e-01 |
| INTERLEUKIN 6 SIGNALING | 10 | 4.33e-01 | 1.43e-01 | 6.50e-01 |
| TNF SIGNALING | 43 | 1.05e-01 | 1.43e-01 | 2.85e-01 |
| POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 66 | 4.46e-02 | -1.43e-01 | 1.59e-01 |
| METABOLISM OF STEROIDS | 117 | 7.75e-03 | 1.43e-01 | 4.80e-02 |
| REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA | 13 | 3.74e-01 | 1.42e-01 | 6.07e-01 |
| GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | 23 | 2.38e-01 | 1.42e-01 | 4.78e-01 |
| FRS MEDIATED FGFR4 SIGNALING | 15 | 3.41e-01 | 1.42e-01 | 5.84e-01 |
| CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | 19 | 2.84e-01 | 1.42e-01 | 5.25e-01 |
| DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING | 59 | 5.99e-02 | 1.42e-01 | 1.93e-01 |
| ASSEMBLY OF THE PRE REPLICATIVE COMPLEX | 64 | 5.12e-02 | 1.41e-01 | 1.74e-01 |
| CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER | 26 | 2.14e-01 | 1.41e-01 | 4.51e-01 |
| POLO LIKE KINASE MEDIATED EVENTS | 14 | 3.66e-01 | 1.39e-01 | 6.05e-01 |
| ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION | 95 | 1.89e-02 | 1.39e-01 | 8.61e-02 |
| TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | 17 | 3.20e-01 | 1.39e-01 | 5.64e-01 |
| SIGNALING BY FLT3 ITD AND TKD MUTANTS | 16 | 3.36e-01 | -1.39e-01 | 5.79e-01 |
| GLUTATHIONE CONJUGATION | 30 | 1.89e-01 | 1.39e-01 | 4.20e-01 |
| NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 | 11 | 4.26e-01 | -1.39e-01 | 6.46e-01 |
| FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | 119 | 9.07e-03 | 1.39e-01 | 5.24e-02 |
| DISEASES OF GLYCOSYLATION | 123 | 8.06e-03 | 1.38e-01 | 4.90e-02 |
| EPIGENETIC REGULATION OF GENE EXPRESSION | 107 | 1.35e-02 | -1.38e-01 | 6.89e-02 |
| PHASE II CONJUGATION OF COMPOUNDS | 64 | 5.64e-02 | 1.38e-01 | 1.87e-01 |
| PURINE CATABOLISM | 16 | 3.40e-01 | 1.38e-01 | 5.84e-01 |
| PEPTIDE LIGAND BINDING RECEPTORS | 112 | 1.19e-02 | 1.38e-01 | 6.42e-02 |
| UNWINDING OF DNA | 12 | 4.09e-01 | 1.38e-01 | 6.28e-01 |
| ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS | 69 | 4.84e-02 | -1.37e-01 | 1.68e-01 |
| SARS COV INFECTIONS | 140 | 5.04e-03 | 1.37e-01 | 3.47e-02 |
| SEMA3A PAK DEPENDENT AXON REPULSION | 16 | 3.42e-01 | 1.37e-01 | 5.85e-01 |
| NEURONAL SYSTEM | 370 | 6.14e-06 | 1.37e-01 | 2.07e-04 |
| INTERLEUKIN 20 FAMILY SIGNALING | 14 | 3.76e-01 | -1.37e-01 | 6.07e-01 |
| SIGNALING BY NTRKS | 129 | 7.43e-03 | 1.37e-01 | 4.71e-02 |
| ZINC TRANSPORTERS | 16 | 3.46e-01 | 1.36e-01 | 5.88e-01 |
| RMTS METHYLATE HISTONE ARGININES | 47 | 1.07e-01 | -1.36e-01 | 2.88e-01 |
| SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER | 15 | 3.63e-01 | 1.36e-01 | 6.02e-01 |
| DISORDERS OF TRANSMEMBRANE TRANSPORTERS | 146 | 4.69e-03 | 1.36e-01 | 3.37e-02 |
| PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE | 49 | 1.01e-01 | 1.36e-01 | 2.78e-01 |
| RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY | 96 | 2.21e-02 | -1.35e-01 | 9.64e-02 |
| SIGNALING BY RETINOIC ACID | 33 | 1.80e-01 | 1.35e-01 | 4.08e-01 |
| INNATE IMMUNE SYSTEM | 779 | 1.82e-10 | 1.35e-01 | 1.95e-08 |
| BIOLOGICAL OXIDATIONS | 126 | 9.04e-03 | 1.35e-01 | 5.24e-02 |
| METABOLISM OF AMINO ACIDS AND DERIVATIVES | 316 | 3.95e-05 | 1.35e-01 | 8.95e-04 |
| SHC MEDIATED CASCADE FGFR3 | 13 | 4.01e-01 | 1.35e-01 | 6.24e-01 |
| LYSOSPHINGOLIPID AND LPA RECEPTORS | 13 | 4.02e-01 | 1.34e-01 | 6.24e-01 |
| NONSENSE MEDIATED DECAY NMD | 110 | 1.52e-02 | -1.34e-01 | 7.57e-02 |
| INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL | 15 | 3.70e-01 | 1.34e-01 | 6.07e-01 |
| RAS PROCESSING | 24 | 2.58e-01 | 1.34e-01 | 5.02e-01 |
| SHC1 EVENTS IN ERBB4 SIGNALING | 13 | 4.05e-01 | 1.33e-01 | 6.24e-01 |
| DNA REPLICATION | 122 | 1.10e-02 | 1.33e-01 | 6.05e-02 |
| SUMOYLATION OF INTRACELLULAR RECEPTORS | 27 | 2.31e-01 | 1.33e-01 | 4.71e-01 |
| IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | 10 | 4.66e-01 | 1.33e-01 | 6.77e-01 |
| INTERLEUKIN 1 SIGNALING | 96 | 2.43e-02 | 1.33e-01 | 1.02e-01 |
| ADAPTIVE IMMUNE SYSTEM | 611 | 2.36e-08 | 1.33e-01 | 1.70e-06 |
| ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS | 19 | 3.17e-01 | 1.33e-01 | 5.62e-01 |
| SIGNALING BY EGFR | 47 | 1.16e-01 | 1.32e-01 | 3.03e-01 |
| GPVI MEDIATED ACTIVATION CASCADE | 31 | 2.02e-01 | 1.32e-01 | 4.36e-01 |
| ASYMMETRIC LOCALIZATION OF PCP PROTEINS | 62 | 7.33e-02 | 1.32e-01 | 2.21e-01 |
| REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF | 56 | 8.88e-02 | 1.32e-01 | 2.55e-01 |
| PHASE I FUNCTIONALIZATION OF COMPOUNDS | 59 | 8.07e-02 | 1.31e-01 | 2.38e-01 |
| CD209 DC SIGN SIGNALING | 18 | 3.35e-01 | 1.31e-01 | 5.78e-01 |
| OTHER SEMAPHORIN INTERACTIONS | 19 | 3.25e-01 | -1.30e-01 | 5.69e-01 |
| CYTOSOLIC SULFONATION OF SMALL MOLECULES | 15 | 3.82e-01 | 1.30e-01 | 6.09e-01 |
| HOMOLOGY DIRECTED REPAIR | 111 | 1.92e-02 | -1.29e-01 | 8.70e-02 |
| TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | 11 | 4.61e-01 | 1.28e-01 | 6.75e-01 |
| ESTROGEN DEPENDENT GENE EXPRESSION | 108 | 2.15e-02 | -1.28e-01 | 9.45e-02 |
| MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES | 31 | 2.17e-01 | 1.28e-01 | 4.53e-01 |
| DAP12 INTERACTIONS | 30 | 2.25e-01 | -1.28e-01 | 4.62e-01 |
| PI3K EVENTS IN ERBB2 SIGNALING | 15 | 3.91e-01 | -1.28e-01 | 6.16e-01 |
| NR1H2 AND NR1H3 MEDIATED SIGNALING | 38 | 1.72e-01 | -1.28e-01 | 3.96e-01 |
| HIV INFECTION | 221 | 1.07e-03 | 1.28e-01 | 1.14e-02 |
| SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS | 12 | 4.43e-01 | 1.28e-01 | 6.58e-01 |
| SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION | 28 | 2.45e-01 | -1.27e-01 | 4.85e-01 |
| GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION | 26 | 2.63e-01 | 1.27e-01 | 5.03e-01 |
| SIGNALING BY VEGF | 103 | 2.63e-02 | 1.27e-01 | 1.07e-01 |
| S PHASE | 154 | 6.67e-03 | 1.27e-01 | 4.30e-02 |
| NUCLEAR SIGNALING BY ERBB4 | 31 | 2.22e-01 | 1.27e-01 | 4.59e-01 |
| ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING | 29 | 2.38e-01 | 1.27e-01 | 4.78e-01 |
| PI METABOLISM | 80 | 5.04e-02 | 1.27e-01 | 1.73e-01 |
| NEGATIVE REGULATION OF FGFR1 SIGNALING | 27 | 2.56e-01 | 1.26e-01 | 5.00e-01 |
| REGULATION OF TNFR1 SIGNALING | 34 | 2.03e-01 | 1.26e-01 | 4.36e-01 |
| REGULATION OF BACH1 ACTIVITY | 11 | 4.69e-01 | 1.26e-01 | 6.79e-01 |
| TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT | 18 | 3.55e-01 | 1.26e-01 | 5.98e-01 |
| PEXOPHAGY | 11 | 4.71e-01 | 1.26e-01 | 6.80e-01 |
| SIGNALING BY GPCR | 487 | 2.25e-06 | 1.25e-01 | 1.02e-04 |
| FORMATION OF INCISION COMPLEX IN GG NER | 43 | 1.56e-01 | 1.25e-01 | 3.71e-01 |
| FGFR2 MUTANT RECEPTOR ACTIVATION | 27 | 2.61e-01 | -1.25e-01 | 5.02e-01 |
| TIE2 SIGNALING | 17 | 3.73e-01 | 1.25e-01 | 6.07e-01 |
| FORMATION OF THE CORNIFIED ENVELOPE | 32 | 2.23e-01 | 1.24e-01 | 4.60e-01 |
| TRANSLESION SYNTHESIS BY POLK | 17 | 3.75e-01 | -1.24e-01 | 6.07e-01 |
| CD28 DEPENDENT PI3K AKT SIGNALING | 21 | 3.24e-01 | 1.24e-01 | 5.69e-01 |
| JOSEPHIN DOMAIN DUBS | 11 | 4.75e-01 | 1.24e-01 | 6.81e-01 |
| SIGNALING BY ERBB4 | 57 | 1.05e-01 | 1.24e-01 | 2.85e-01 |
| DISEASES OF IMMUNE SYSTEM | 25 | 2.83e-01 | -1.24e-01 | 5.24e-01 |
| PROGRAMMED CELL DEATH | 186 | 3.59e-03 | 1.24e-01 | 2.73e-02 |
| RHOBTB GTPASE CYCLE | 35 | 2.05e-01 | 1.24e-01 | 4.38e-01 |
| TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | 10 | 4.99e-01 | 1.24e-01 | 7.04e-01 |
| RHOV GTPASE CYCLE | 33 | 2.19e-01 | 1.24e-01 | 4.57e-01 |
| POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | 62 | 9.33e-02 | 1.23e-01 | 2.64e-01 |
| REGULATION OF FZD BY UBIQUITINATION | 19 | 3.55e-01 | 1.22e-01 | 5.98e-01 |
| HS GAG DEGRADATION | 20 | 3.43e-01 | 1.22e-01 | 5.86e-01 |
| FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES | 24 | 3.00e-01 | -1.22e-01 | 5.45e-01 |
| ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | 288 | 3.75e-04 | 1.22e-01 | 5.20e-03 |
| RESPIRATORY ELECTRON TRANSPORT | 102 | 3.35e-02 | -1.22e-01 | 1.30e-01 |
| CHROMATIN MODIFYING ENZYMES | 223 | 1.76e-03 | -1.22e-01 | 1.67e-02 |
| REGULATION OF IFNA SIGNALING | 12 | 4.67e-01 | -1.21e-01 | 6.77e-01 |
| MITOTIC SPINDLE CHECKPOINT | 97 | 3.96e-02 | 1.21e-01 | 1.45e-01 |
| APOPTOSIS | 164 | 7.61e-03 | 1.21e-01 | 4.77e-02 |
| GLYCOLYSIS | 67 | 8.78e-02 | 1.21e-01 | 2.53e-01 |
| REGULATION OF RUNX2 EXPRESSION AND ACTIVITY | 68 | 8.57e-02 | 1.21e-01 | 2.49e-01 |
| PYRIMIDINE SALVAGE | 10 | 5.10e-01 | 1.20e-01 | 7.10e-01 |
| CONDENSATION OF PROPHASE CHROMOSOMES | 31 | 2.47e-01 | -1.20e-01 | 4.88e-01 |
| ACTIVATION OF SMO | 16 | 4.05e-01 | 1.20e-01 | 6.24e-01 |
| RHO GTPASE EFFECTORS | 253 | 1.05e-03 | 1.20e-01 | 1.13e-02 |
| NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 23 | 3.20e-01 | 1.20e-01 | 5.64e-01 |
| MYD88 INDEPENDENT TLR4 CASCADE | 93 | 4.62e-02 | 1.20e-01 | 1.63e-01 |
| CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND | 10 | 5.13e-01 | 1.19e-01 | 7.12e-01 |
| OTHER INTERLEUKIN SIGNALING | 20 | 3.56e-01 | 1.19e-01 | 5.98e-01 |
| DNA DAMAGE RECOGNITION IN GG NER | 38 | 2.03e-01 | 1.19e-01 | 4.36e-01 |
| RNA POLYMERASE III TRANSCRIPTION TERMINATION | 23 | 3.24e-01 | -1.19e-01 | 5.69e-01 |
| DISEASES OF METABOLISM | 197 | 4.19e-03 | 1.18e-01 | 3.08e-02 |
| ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING | 21 | 3.48e-01 | 1.18e-01 | 5.90e-01 |
| SIGNALING BY WNT IN CANCER | 31 | 2.55e-01 | 1.18e-01 | 5.00e-01 |
| IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | 21 | 3.49e-01 | 1.18e-01 | 5.90e-01 |
| APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | 34 | 2.34e-01 | 1.18e-01 | 4.75e-01 |
| CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 | 11 | 4.99e-01 | 1.18e-01 | 7.04e-01 |
| FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF | 14 | 4.46e-01 | -1.18e-01 | 6.60e-01 |
| SUMOYLATION OF IMMUNE RESPONSE PROTEINS | 11 | 5.01e-01 | 1.17e-01 | 7.05e-01 |
| TELOMERE EXTENSION BY TELOMERASE | 22 | 3.45e-01 | 1.16e-01 | 5.88e-01 |
| TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY | 29 | 2.80e-01 | 1.16e-01 | 5.22e-01 |
| METABOLISM OF FOLATE AND PTERINES | 15 | 4.37e-01 | 1.16e-01 | 6.54e-01 |
| TRIGLYCERIDE METABOLISM | 24 | 3.26e-01 | 1.16e-01 | 5.70e-01 |
| INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION | 15 | 4.39e-01 | -1.16e-01 | 6.56e-01 |
| ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | 32 | 2.59e-01 | 1.15e-01 | 5.02e-01 |
| METABOLISM OF VITAMINS AND COFACTORS | 152 | 1.43e-02 | 1.15e-01 | 7.21e-02 |
| SHC MEDIATED CASCADE FGFR4 | 13 | 4.73e-01 | 1.15e-01 | 6.80e-01 |
| TNFR2 NON CANONICAL NF KB PATHWAY | 79 | 7.77e-02 | 1.15e-01 | 2.31e-01 |
| M PHASE | 344 | 2.63e-04 | 1.15e-01 | 3.99e-03 |
| INFLUENZA INFECTION | 146 | 1.69e-02 | -1.15e-01 | 7.96e-02 |
| DNA DOUBLE STRAND BREAK REPAIR | 140 | 1.97e-02 | -1.14e-01 | 8.82e-02 |
| MITOCHONDRIAL CALCIUM ION TRANSPORT | 23 | 3.44e-01 | 1.14e-01 | 5.87e-01 |
| MITOTIC G2 G2 M PHASES | 184 | 7.80e-03 | 1.14e-01 | 4.80e-02 |
| GENE SILENCING BY RNA | 86 | 6.82e-02 | -1.14e-01 | 2.13e-01 |
| NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 23 | 3.46e-01 | -1.13e-01 | 5.88e-01 |
| MITOTIC TELOPHASE CYTOKINESIS | 13 | 4.80e-01 | -1.13e-01 | 6.84e-01 |
| SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | 20 | 3.82e-01 | -1.13e-01 | 6.09e-01 |
| MAPK6 MAPK4 SIGNALING | 83 | 7.68e-02 | 1.12e-01 | 2.30e-01 |
| SIGNALING BY SCF KIT | 41 | 2.13e-01 | 1.12e-01 | 4.51e-01 |
| SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | 53 | 1.59e-01 | 1.12e-01 | 3.77e-01 |
| ORGANELLE BIOGENESIS AND MAINTENANCE | 284 | 1.22e-03 | 1.12e-01 | 1.28e-02 |
| CYCLIN D ASSOCIATED EVENTS IN G1 | 45 | 1.96e-01 | 1.11e-01 | 4.30e-01 |
| CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY | 13 | 4.87e-01 | -1.11e-01 | 6.91e-01 |
| COSTIMULATION BY THE CD28 FAMILY | 51 | 1.71e-01 | 1.11e-01 | 3.94e-01 |
| BILE ACID AND BILE SALT METABOLISM | 26 | 3.28e-01 | 1.11e-01 | 5.72e-01 |
| INWARDLY RECTIFYING K CHANNELS | 32 | 2.78e-01 | 1.11e-01 | 5.21e-01 |
| SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX | 12 | 5.07e-01 | -1.11e-01 | 7.10e-01 |
| KERATINIZATION | 33 | 2.72e-01 | 1.11e-01 | 5.13e-01 |
| SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL | 25 | 3.41e-01 | 1.10e-01 | 5.84e-01 |
| TRAF6 MEDIATED NF KB ACTIVATION | 22 | 3.72e-01 | -1.10e-01 | 6.07e-01 |
| INTERLEUKIN 1 FAMILY SIGNALING | 123 | 3.59e-02 | 1.10e-01 | 1.34e-01 |
| EPHA MEDIATED GROWTH CONE COLLAPSE | 29 | 3.07e-01 | -1.10e-01 | 5.52e-01 |
| EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION | 27 | 3.25e-01 | 1.09e-01 | 5.69e-01 |
| MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION | 16 | 4.50e-01 | 1.09e-01 | 6.63e-01 |
| SIGNALING BY FGFR2 IN DISEASE | 37 | 2.51e-01 | -1.09e-01 | 4.93e-01 |
| TRANSPORT OF SMALL MOLECULES | 584 | 8.00e-06 | 1.08e-01 | 2.48e-04 |
| HEMOSTASIS | 478 | 5.09e-05 | 1.08e-01 | 1.10e-03 |
| METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS | 102 | 5.92e-02 | 1.08e-01 | 1.92e-01 |
| CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION | 348 | 5.90e-04 | 1.07e-01 | 7.24e-03 |
| CELL CYCLE MITOTIC | 479 | 6.18e-05 | 1.07e-01 | 1.21e-03 |
| NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 20 | 4.08e-01 | -1.07e-01 | 6.27e-01 |
| PTEN REGULATION | 133 | 3.35e-02 | 1.07e-01 | 1.30e-01 |
| ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES | 52 | 1.85e-01 | -1.06e-01 | 4.15e-01 |
| RHOBTB1 GTPASE CYCLE | 23 | 3.78e-01 | 1.06e-01 | 6.07e-01 |
| BETA CATENIN INDEPENDENT WNT SIGNALING | 140 | 3.07e-02 | 1.06e-01 | 1.22e-01 |
| SIGNALING BY WNT | 274 | 2.66e-03 | 1.06e-01 | 2.25e-02 |
| FLT3 SIGNALING IN DISEASE | 28 | 3.35e-01 | -1.05e-01 | 5.78e-01 |
| DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX | 41 | 2.45e-01 | 1.05e-01 | 4.85e-01 |
| BIOTIN TRANSPORT AND METABOLISM | 11 | 5.47e-01 | -1.05e-01 | 7.40e-01 |
| SIGNALING BY PTK6 | 50 | 2.03e-01 | 1.04e-01 | 4.36e-01 |
| TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 43 | 2.40e-01 | -1.04e-01 | 4.80e-01 |
| RNA POLYMERASE I TRANSCRIPTION TERMINATION | 31 | 3.19e-01 | -1.03e-01 | 5.64e-01 |
| EPH EPHRIN MEDIATED REPULSION OF CELLS | 51 | 2.03e-01 | 1.03e-01 | 4.36e-01 |
| MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS | 13 | 5.20e-01 | -1.03e-01 | 7.17e-01 |
| RUNX3 REGULATES NOTCH SIGNALING | 13 | 5.21e-01 | -1.03e-01 | 7.17e-01 |
| ACTIVATION OF MATRIX METALLOPROTEINASES | 15 | 4.90e-01 | 1.03e-01 | 6.93e-01 |
| INITIAL TRIGGERING OF COMPLEMENT | 12 | 5.38e-01 | 1.03e-01 | 7.34e-01 |
| ACTIVATION OF THE PRE REPLICATIVE COMPLEX | 30 | 3.31e-01 | 1.02e-01 | 5.75e-01 |
| SENSORY PERCEPTION | 162 | 2.55e-02 | -1.02e-01 | 1.06e-01 |
| RHOH GTPASE CYCLE | 37 | 2.86e-01 | 1.01e-01 | 5.26e-01 |
| SIGNALING BY NOTCH4 | 83 | 1.10e-01 | 1.01e-01 | 2.93e-01 |
| SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS | 41 | 2.62e-01 | 1.01e-01 | 5.03e-01 |
| ECM PROTEOGLYCANS | 68 | 1.51e-01 | -1.01e-01 | 3.68e-01 |
| PHASE 0 RAPID DEPOLARISATION | 28 | 3.57e-01 | -1.01e-01 | 5.99e-01 |
| SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R | 46 | 2.39e-01 | -1.00e-01 | 4.79e-01 |
| INTERLEUKIN 7 SIGNALING | 19 | 4.49e-01 | -1.00e-01 | 6.63e-01 |
| ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION | 119 | 5.91e-02 | 1.00e-01 | 1.92e-01 |
| RAC2 GTPASE CYCLE | 87 | 1.07e-01 | 1.00e-01 | 2.87e-01 |
| MEIOTIC RECOMBINATION | 42 | 2.63e-01 | -9.98e-02 | 5.03e-01 |
| PHASE 4 RESTING MEMBRANE POTENTIAL | 14 | 5.19e-01 | -9.96e-02 | 7.17e-01 |
| MISCELLANEOUS TRANSPORT AND BINDING EVENTS | 21 | 4.30e-01 | 9.94e-02 | 6.49e-01 |
| RHOG GTPASE CYCLE | 74 | 1.40e-01 | 9.93e-02 | 3.49e-01 |
| VIRAL MESSENGER RNA SYNTHESIS | 42 | 2.66e-01 | -9.91e-02 | 5.07e-01 |
| FANCONI ANEMIA PATHWAY | 36 | 3.06e-01 | -9.87e-02 | 5.50e-01 |
| CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | 11 | 5.72e-01 | 9.84e-02 | 7.61e-01 |
| REGULATION OF PTEN GENE TRANSCRIPTION | 58 | 1.96e-01 | 9.83e-02 | 4.29e-01 |
| NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 26 | 3.87e-01 | 9.81e-02 | 6.12e-01 |
| SIGNALING BY CSF3 G CSF | 29 | 3.61e-01 | 9.80e-02 | 6.02e-01 |
| INFLAMMASOMES | 19 | 4.62e-01 | -9.74e-02 | 6.76e-01 |
| APC CDC20 MEDIATED DEGRADATION OF NEK2A | 24 | 4.11e-01 | 9.69e-02 | 6.28e-01 |
| METABOLISM OF STEROID HORMONES | 22 | 4.32e-01 | 9.68e-02 | 6.49e-01 |
| POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE | 25 | 4.03e-01 | 9.67e-02 | 6.24e-01 |
| ABC TRANSPORTERS IN LIPID HOMEOSTASIS | 14 | 5.33e-01 | 9.62e-02 | 7.31e-01 |
| RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN | 37 | 3.12e-01 | -9.62e-02 | 5.54e-01 |
| TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | 16 | 5.07e-01 | 9.58e-02 | 7.10e-01 |
| TNFR1 INDUCED PROAPOPTOTIC SIGNALING | 12 | 5.67e-01 | 9.55e-02 | 7.56e-01 |
| UB SPECIFIC PROCESSING PROTEASES | 169 | 3.33e-02 | 9.50e-02 | 1.30e-01 |
| HEME BIOSYNTHESIS | 13 | 5.55e-01 | 9.46e-02 | 7.49e-01 |
| DNA DAMAGE BYPASS | 47 | 2.63e-01 | -9.45e-02 | 5.03e-01 |
| RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | 125 | 6.85e-02 | -9.44e-02 | 2.13e-01 |
| G PROTEIN BETA GAMMA SIGNALLING | 31 | 3.64e-01 | 9.42e-02 | 6.02e-01 |
| ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K | 11 | 5.90e-01 | -9.39e-02 | 7.76e-01 |
| NGF STIMULATED TRANSCRIPTION | 36 | 3.30e-01 | 9.39e-02 | 5.73e-01 |
| ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | 16 | 5.16e-01 | 9.38e-02 | 7.13e-01 |
| ONCOGENIC MAPK SIGNALING | 77 | 1.55e-01 | 9.38e-02 | 3.71e-01 |
| ORGANIC CATION ANION ZWITTERION TRANSPORT | 11 | 5.92e-01 | -9.33e-02 | 7.78e-01 |
| TRANSLATION | 287 | 6.66e-03 | 9.32e-02 | 4.30e-02 |
| REPRODUCTION | 81 | 1.48e-01 | -9.29e-02 | 3.65e-01 |
| SCAVENGING BY CLASS A RECEPTORS | 14 | 5.48e-01 | 9.27e-02 | 7.40e-01 |
| REGULATED PROTEOLYSIS OF P75NTR | 12 | 5.78e-01 | 9.27e-02 | 7.67e-01 |
| CELL CELL JUNCTION ORGANIZATION | 48 | 2.67e-01 | 9.27e-02 | 5.07e-01 |
| NON INTEGRIN MEMBRANE ECM INTERACTIONS | 57 | 2.30e-01 | -9.19e-02 | 4.71e-01 |
| NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION | 21 | 4.66e-01 | 9.19e-02 | 6.77e-01 |
| SHC1 EVENTS IN ERBB2 SIGNALING | 21 | 4.66e-01 | 9.19e-02 | 6.77e-01 |
| NOTCH HLH TRANSCRIPTION PATHWAY | 28 | 4.00e-01 | -9.18e-02 | 6.24e-01 |
| NEGATIVE REGULATION OF FGFR2 SIGNALING | 28 | 4.02e-01 | 9.14e-02 | 6.24e-01 |
| SIGNALING BY INSULIN RECEPTOR | 65 | 2.03e-01 | 9.13e-02 | 4.36e-01 |
| INTERLEUKIN 17 SIGNALING | 68 | 1.93e-01 | 9.12e-02 | 4.26e-01 |
| TRANSCRIPTIONAL REGULATION BY SMALL RNAS | 65 | 2.04e-01 | -9.12e-02 | 4.36e-01 |
| RNA POLYMERASE I PROMOTER ESCAPE | 51 | 2.61e-01 | -9.10e-02 | 5.02e-01 |
| HIV ELONGATION ARREST AND RECOVERY | 32 | 3.73e-01 | -9.10e-02 | 6.07e-01 |
| RHOJ GTPASE CYCLE | 54 | 2.48e-01 | 9.10e-02 | 4.89e-01 |
| NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 69 | 1.92e-01 | -9.09e-02 | 4.24e-01 |
| NICOTINAMIDE SALVAGING | 14 | 5.57e-01 | -9.06e-02 | 7.50e-01 |
| SIGNALING BY NTRK2 TRKB | 24 | 4.43e-01 | 9.04e-02 | 6.58e-01 |
| ACTIVATION OF GENE EXPRESSION BY SREBF SREBP | 43 | 3.06e-01 | 9.02e-02 | 5.51e-01 |
| METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS | 10 | 6.23e-01 | 8.99e-02 | 7.98e-01 |
| PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS | 20 | 4.87e-01 | 8.97e-02 | 6.91e-01 |
| INTRACELLULAR SIGNALING BY SECOND MESSENGERS | 284 | 9.57e-03 | 8.95e-02 | 5.43e-02 |
| SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS | 73 | 1.86e-01 | -8.95e-02 | 4.17e-01 |
| RAF INDEPENDENT MAPK1 3 ACTIVATION | 21 | 4.78e-01 | 8.95e-02 | 6.83e-01 |
| INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING | 77 | 1.75e-01 | 8.94e-02 | 4.00e-01 |
| SIGNALING BY BRAF AND RAF FUSIONS | 60 | 2.32e-01 | 8.93e-02 | 4.72e-01 |
| CELL CYCLE CHECKPOINTS | 245 | 1.65e-02 | 8.90e-02 | 7.89e-02 |
| SLC MEDIATED TRANSMEMBRANE TRANSPORT | 192 | 3.42e-02 | 8.87e-02 | 1.31e-01 |
| NEGATIVE REGULATION OF FLT3 | 14 | 5.66e-01 | -8.86e-02 | 7.56e-01 |
| NEUROTRANSMITTER RELEASE CYCLE | 48 | 2.89e-01 | 8.86e-02 | 5.30e-01 |
| SIGNALING BY FGFR1 | 44 | 3.10e-01 | 8.85e-02 | 5.53e-01 |
| BASE EXCISION REPAIR AP SITE FORMATION | 33 | 3.83e-01 | -8.78e-02 | 6.09e-01 |
| GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER | 25 | 4.48e-01 | -8.77e-02 | 6.62e-01 |
| ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY | 11 | 6.16e-01 | 8.74e-02 | 7.95e-01 |
| MITOTIC PROPHASE | 98 | 1.36e-01 | 8.73e-02 | 3.40e-01 |
| CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | 31 | 4.01e-01 | -8.72e-02 | 6.24e-01 |
| TCF DEPENDENT SIGNALING IN RESPONSE TO WNT | 181 | 4.33e-02 | 8.72e-02 | 1.56e-01 |
| TRAFFICKING OF AMPA RECEPTORS | 31 | 4.02e-01 | 8.70e-02 | 6.24e-01 |
| FORMATION OF TC NER PRE INCISION COMPLEX | 53 | 2.74e-01 | 8.69e-02 | 5.15e-01 |
| NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 11 | 6.18e-01 | -8.67e-02 | 7.95e-01 |
| INTEGRIN SIGNALING | 24 | 4.63e-01 | 8.66e-02 | 6.76e-01 |
| RESOLUTION OF ABASIC SITES AP SITES | 38 | 3.59e-01 | -8.60e-02 | 6.00e-01 |
| G PROTEIN ACTIVATION | 23 | 4.76e-01 | 8.59e-02 | 6.81e-01 |
| INTERLEUKIN 2 FAMILY SIGNALING | 32 | 4.01e-01 | -8.58e-02 | 6.24e-01 |
| TRANSCRIPTIONAL REGULATION BY E2F6 | 34 | 3.91e-01 | 8.51e-02 | 6.16e-01 |
| MUSCLE CONTRACTION | 161 | 6.31e-02 | -8.49e-02 | 2.00e-01 |
| TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | 13 | 5.97e-01 | -8.48e-02 | 7.82e-01 |
| MITOTIC PROMETAPHASE | 177 | 5.23e-02 | 8.47e-02 | 1.76e-01 |
| SIGNALING BY RECEPTOR TYROSINE KINASES | 462 | 1.90e-03 | 8.45e-02 | 1.77e-02 |
| NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS | 12 | 6.14e-01 | 8.41e-02 | 7.95e-01 |
| INTERLEUKIN 6 FAMILY SIGNALING | 20 | 5.16e-01 | 8.39e-02 | 7.13e-01 |
| PI 3K CASCADE FGFR4 | 13 | 6.01e-01 | -8.38e-02 | 7.83e-01 |
| ADHERENS JUNCTIONS INTERACTIONS | 30 | 4.32e-01 | 8.29e-02 | 6.49e-01 |
| AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | 14 | 5.92e-01 | 8.26e-02 | 7.78e-01 |
| INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | 29 | 4.42e-01 | 8.25e-02 | 6.58e-01 |
| SIGNALING BY INTERLEUKINS | 349 | 8.51e-03 | 8.21e-02 | 5.06e-02 |
| GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER | 84 | 1.94e-01 | 8.21e-02 | 4.26e-01 |
| RRNA PROCESSING IN THE MITOCHONDRION | 10 | 6.53e-01 | 8.20e-02 | 8.18e-01 |
| RA BIOSYNTHESIS PATHWAY | 13 | 6.11e-01 | -8.15e-02 | 7.94e-01 |
| NEPHRIN FAMILY INTERACTIONS | 23 | 5.00e-01 | 8.12e-02 | 7.05e-01 |
| TOLL LIKE RECEPTOR CASCADES | 138 | 1.02e-01 | 8.07e-02 | 2.80e-01 |
| DEREGULATED CDK5 TRIGGERS MULTIPLE NEURODEGENERATIVE PATHWAYS IN ALZHEIMER S DISEASE MODELS | 19 | 5.43e-01 | 8.06e-02 | 7.37e-01 |
| TRNA PROCESSING IN THE NUCLEUS | 56 | 2.97e-01 | 8.05e-02 | 5.44e-01 |
| HDR THROUGH MMEJ ALT NHEJ | 10 | 6.59e-01 | -8.05e-02 | 8.22e-01 |
| CELL CYCLE | 598 | 8.03e-04 | 8.05e-02 | 9.14e-03 |
| HCMV INFECTION | 107 | 1.52e-01 | 8.02e-02 | 3.69e-01 |
| PLATELET CALCIUM HOMEOSTASIS | 26 | 4.80e-01 | -8.00e-02 | 6.84e-01 |
| DOWNSTREAM SIGNAL TRANSDUCTION | 29 | 4.57e-01 | 7.99e-02 | 6.71e-01 |
| RHOD GTPASE CYCLE | 51 | 3.24e-01 | 7.98e-02 | 5.69e-01 |
| ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | 23 | 5.08e-01 | 7.97e-02 | 7.10e-01 |
| ENDOGENOUS STEROLS | 20 | 5.37e-01 | -7.97e-02 | 7.34e-01 |
| PROCESSING OF DNA DOUBLE STRAND BREAK ENDS | 74 | 2.40e-01 | -7.90e-02 | 4.80e-01 |
| ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS | 23 | 5.13e-01 | -7.87e-02 | 7.12e-01 |
| NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION | 58 | 3.02e-01 | 7.85e-02 | 5.48e-01 |
| ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION | 36 | 4.17e-01 | -7.82e-02 | 6.35e-01 |
| O LINKED GLYCOSYLATION | 85 | 2.15e-01 | 7.79e-02 | 4.51e-01 |
| TRANSCRIPTIONAL REGULATION BY RUNX3 | 94 | 1.92e-01 | 7.79e-02 | 4.24e-01 |
| MAP2K AND MAPK ACTIVATION | 36 | 4.19e-01 | 7.78e-02 | 6.38e-01 |
| TRANSCRIPTIONAL REGULATION BY RUNX1 | 183 | 7.27e-02 | -7.70e-02 | 2.21e-01 |
| IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS | 14 | 6.18e-01 | 7.69e-02 | 7.95e-01 |
| TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST | 13 | 6.32e-01 | -7.66e-02 | 8.03e-01 |
| DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS | 369 | 1.17e-02 | 7.66e-02 | 6.34e-02 |
| METABOLISM OF COFACTORS | 19 | 5.64e-01 | 7.65e-02 | 7.55e-01 |
| IRS MEDIATED SIGNALLING | 41 | 3.97e-01 | -7.64e-02 | 6.24e-01 |
| NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | 44 | 3.81e-01 | 7.64e-02 | 6.09e-01 |
| INFECTIOUS DISEASE | 739 | 4.47e-04 | 7.62e-02 | 5.97e-03 |
| MYOGENESIS | 25 | 5.11e-01 | -7.60e-02 | 7.10e-01 |
| APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B | 21 | 5.48e-01 | 7.58e-02 | 7.40e-01 |
| RAC3 GTPASE CYCLE | 90 | 2.20e-01 | 7.49e-02 | 4.57e-01 |
| IRAK4 DEFICIENCY TLR2 4 | 14 | 6.29e-01 | -7.45e-02 | 8.01e-01 |
| RND3 GTPASE CYCLE | 38 | 4.28e-01 | 7.44e-02 | 6.47e-01 |
| PRE NOTCH EXPRESSION AND PROCESSING | 68 | 2.90e-01 | -7.42e-02 | 5.32e-01 |
| FOXO MEDIATED TRANSCRIPTION | 57 | 3.33e-01 | -7.41e-02 | 5.77e-01 |
| RHO GTPASES ACTIVATE CIT | 18 | 5.88e-01 | -7.39e-02 | 7.75e-01 |
| SUMOYLATION OF DNA REPLICATION PROTEINS | 43 | 4.04e-01 | 7.35e-02 | 6.24e-01 |
| P38MAPK EVENTS | 13 | 6.48e-01 | 7.31e-02 | 8.15e-01 |
| G ALPHA S SIGNALLING EVENTS | 108 | 1.90e-01 | 7.30e-02 | 4.22e-01 |
| TRP CHANNELS | 20 | 5.75e-01 | -7.24e-02 | 7.64e-01 |
| FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES | 15 | 6.27e-01 | 7.24e-02 | 8.01e-01 |
| MICRORNA MIRNA BIOGENESIS | 24 | 5.40e-01 | -7.23e-02 | 7.36e-01 |
| NS1 MEDIATED EFFECTS ON HOST PATHWAYS | 37 | 4.50e-01 | -7.18e-02 | 6.63e-01 |
| FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | 18 | 5.99e-01 | -7.17e-02 | 7.82e-01 |
| RHOU GTPASE CYCLE | 34 | 4.72e-01 | 7.14e-02 | 6.80e-01 |
| BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS | 35 | 4.66e-01 | -7.12e-02 | 6.77e-01 |
| DEUBIQUITINATION | 243 | 5.68e-02 | 7.10e-02 | 1.88e-01 |
| MEIOSIS | 68 | 3.11e-01 | -7.10e-02 | 5.54e-01 |
| SUMOYLATION OF DNA METHYLATION PROTEINS | 16 | 6.23e-01 | -7.09e-02 | 7.98e-01 |
| ONCOGENE INDUCED SENESCENCE | 32 | 4.88e-01 | 7.09e-02 | 6.91e-01 |
| RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | 85 | 2.60e-01 | 7.07e-02 | 5.02e-01 |
| RNA POLYMERASE I TRANSCRIPTION | 71 | 3.04e-01 | -7.06e-02 | 5.50e-01 |
| SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 | 630 | 2.59e-03 | 7.06e-02 | 2.21e-02 |
| NEGATIVE REGULATION OF THE PI3K AKT NETWORK | 97 | 2.33e-01 | 7.01e-02 | 4.73e-01 |
| TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS | 33 | 4.86e-01 | 7.00e-02 | 6.91e-01 |
| SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS | 60 | 3.49e-01 | -7.00e-02 | 5.90e-01 |
| REGULATION OF GENE EXPRESSION IN BETA CELLS | 12 | 6.75e-01 | 6.98e-02 | 8.33e-01 |
| HATS ACETYLATE HISTONES | 97 | 2.36e-01 | -6.97e-02 | 4.76e-01 |
| TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS | 54 | 3.78e-01 | -6.94e-02 | 6.07e-01 |
| GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 12 | 6.78e-01 | -6.92e-02 | 8.34e-01 |
| SUMOYLATION OF TRANSCRIPTION COFACTORS | 42 | 4.41e-01 | -6.87e-02 | 6.58e-01 |
| LEISHMANIA INFECTION | 199 | 9.66e-02 | 6.84e-02 | 2.70e-01 |
| NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | 16 | 6.36e-01 | 6.83e-02 | 8.05e-01 |
| SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | 11 | 6.97e-01 | 6.79e-02 | 8.48e-01 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 | 24 | 5.66e-01 | -6.77e-02 | 7.56e-01 |
| GAB1 SIGNALOSOME | 14 | 6.61e-01 | -6.76e-02 | 8.23e-01 |
| TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 | 12 | 6.85e-01 | 6.76e-02 | 8.40e-01 |
| DEFECTS IN VITAMIN AND COFACTOR METABOLISM | 21 | 5.98e-01 | 6.65e-02 | 7.82e-01 |
| ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | 59 | 3.78e-01 | 6.63e-02 | 6.07e-01 |
| SIGNALING BY NOTCH2 | 33 | 5.10e-01 | 6.63e-02 | 7.10e-01 |
| MAPK FAMILY SIGNALING CASCADES | 290 | 5.28e-02 | 6.62e-02 | 1.77e-01 |
| POTASSIUM CHANNELS | 90 | 2.79e-01 | 6.60e-02 | 5.22e-01 |
| NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 12 | 6.92e-01 | 6.60e-02 | 8.44e-01 |
| INTERLEUKIN 37 SIGNALING | 18 | 6.29e-01 | 6.57e-02 | 8.01e-01 |
| THE PHOTOTRANSDUCTION CASCADE | 22 | 5.94e-01 | -6.57e-02 | 7.79e-01 |
| TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | 33 | 5.15e-01 | 6.55e-02 | 7.13e-01 |
| RNA POLYMERASE III TRANSCRIPTION | 41 | 4.70e-01 | -6.52e-02 | 6.79e-01 |
| SEROTONIN NEUROTRANSMITTER RELEASE CYCLE | 18 | 6.33e-01 | 6.49e-02 | 8.03e-01 |
| MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | 15 | 6.66e-01 | -6.45e-02 | 8.25e-01 |
| RHOA GTPASE CYCLE | 141 | 1.88e-01 | 6.42e-02 | 4.20e-01 |
| PI 3K CASCADE FGFR3 | 13 | 6.89e-01 | -6.41e-02 | 8.43e-01 |
| PLATELET AGGREGATION PLUG FORMATION | 32 | 5.32e-01 | 6.38e-02 | 7.31e-01 |
| CRISTAE FORMATION | 31 | 5.40e-01 | 6.36e-02 | 7.36e-01 |
| POTENTIAL THERAPEUTICS FOR SARS | 77 | 3.34e-01 | 6.36e-02 | 5.78e-01 |
| DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | 42 | 4.76e-01 | -6.36e-02 | 6.81e-01 |
| METABOLISM OF PORPHYRINS | 19 | 6.31e-01 | 6.36e-02 | 8.02e-01 |
| DUAL INCISION IN TC NER | 65 | 3.76e-01 | -6.35e-02 | 6.07e-01 |
| MEIOTIC SYNAPSIS | 44 | 4.67e-01 | -6.33e-02 | 6.77e-01 |
| PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION | 23 | 5.99e-01 | -6.33e-02 | 7.82e-01 |
| SIGNALING BY BMP | 25 | 5.84e-01 | 6.33e-02 | 7.74e-01 |
| LONG TERM POTENTIATION | 23 | 6.00e-01 | 6.32e-02 | 7.82e-01 |
| CELLULAR RESPONSES TO EXTERNAL STIMULI | 607 | 8.07e-03 | 6.32e-02 | 4.90e-02 |
| CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | 12 | 7.06e-01 | 6.30e-02 | 8.56e-01 |
| PROTEIN PROTEIN INTERACTIONS AT SYNAPSES | 85 | 3.17e-01 | 6.28e-02 | 5.62e-01 |
| TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES | 61 | 4.05e-01 | -6.17e-02 | 6.24e-01 |
| CARDIAC CONDUCTION | 107 | 2.71e-01 | -6.17e-02 | 5.12e-01 |
| CELL JUNCTION ORGANIZATION | 73 | 3.64e-01 | 6.15e-02 | 6.02e-01 |
| HIV LIFE CYCLE | 142 | 2.07e-01 | 6.14e-02 | 4.41e-01 |
| G2 M CHECKPOINTS | 136 | 2.16e-01 | 6.14e-02 | 4.53e-01 |
| TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | 43 | 4.87e-01 | -6.12e-02 | 6.91e-01 |
| BASE EXCISION REPAIR | 61 | 4.09e-01 | -6.12e-02 | 6.28e-01 |
| SEMAPHORIN INTERACTIONS | 64 | 3.98e-01 | -6.11e-02 | 6.24e-01 |
| SELENOAMINO ACID METABOLISM | 109 | 2.73e-01 | -6.08e-02 | 5.15e-01 |
| REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO | 10 | 7.41e-01 | 6.03e-02 | 8.69e-01 |
| FGFRL1 MODULATION OF FGFR1 SIGNALING | 10 | 7.42e-01 | -6.02e-02 | 8.69e-01 |
| TRANSCRIPTIONAL REGULATION BY RUNX2 | 108 | 2.81e-01 | 6.01e-02 | 5.22e-01 |
| SIGNALING BY FGFR | 74 | 3.74e-01 | 5.98e-02 | 6.07e-01 |
| P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 12 | 7.22e-01 | -5.93e-02 | 8.67e-01 |
| DNA REPAIR | 296 | 8.10e-02 | -5.90e-02 | 2.38e-01 |
| PLASMA LIPOPROTEIN ASSEMBLY | 12 | 7.24e-01 | 5.89e-02 | 8.67e-01 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 | 20 | 6.49e-01 | 5.88e-02 | 8.15e-01 |
| SODIUM CALCIUM EXCHANGERS | 10 | 7.48e-01 | -5.87e-02 | 8.73e-01 |
| SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | 11 | 7.37e-01 | 5.85e-02 | 8.68e-01 |
| PHOSPHORYLATION OF THE APC C | 17 | 6.79e-01 | 5.80e-02 | 8.34e-01 |
| REGULATION OF SIGNALING BY CBL | 22 | 6.38e-01 | 5.80e-02 | 8.06e-01 |
| DISEASES OF MITOTIC CELL CYCLE | 37 | 5.43e-01 | 5.78e-02 | 7.37e-01 |
| ANTIGEN PROCESSING CROSS PRESENTATION | 96 | 3.29e-01 | 5.77e-02 | 5.72e-01 |
| COLLAGEN DEGRADATION | 52 | 4.73e-01 | -5.75e-02 | 6.80e-01 |
| CELL CELL COMMUNICATION | 106 | 3.09e-01 | 5.72e-02 | 5.53e-01 |
| INHIBITION OF DNA RECOMBINATION AT TELOMERE | 39 | 5.37e-01 | -5.71e-02 | 7.34e-01 |
| OVARIAN TUMOR DOMAIN PROTEASES | 36 | 5.56e-01 | 5.68e-02 | 7.49e-01 |
| NF KB IS ACTIVATED AND SIGNALS SURVIVAL | 12 | 7.36e-01 | -5.62e-02 | 8.68e-01 |
| RHO GTPASES ACTIVATE KTN1 | 11 | 7.48e-01 | 5.60e-02 | 8.73e-01 |
| RRNA PROCESSING | 195 | 1.79e-01 | -5.59e-02 | 4.07e-01 |
| SUMOYLATION | 168 | 2.13e-01 | -5.57e-02 | 4.51e-01 |
| RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | 28 | 6.15e-01 | -5.50e-02 | 7.95e-01 |
| DUAL INCISION IN GG NER | 41 | 5.43e-01 | -5.50e-02 | 7.37e-01 |
| TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS | 28 | 6.17e-01 | 5.47e-02 | 7.95e-01 |
| COLLAGEN FORMATION | 79 | 4.02e-01 | -5.46e-02 | 6.24e-01 |
| DEATH RECEPTOR SIGNALLING | 132 | 2.82e-01 | 5.43e-02 | 5.23e-01 |
| SIGNALING BY TGFB FAMILY MEMBERS | 96 | 3.64e-01 | 5.37e-02 | 6.02e-01 |
| COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES | 63 | 4.63e-01 | -5.34e-02 | 6.76e-01 |
| RET SIGNALING | 38 | 5.69e-01 | 5.34e-02 | 7.58e-01 |
| TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE | 94 | 3.73e-01 | 5.32e-02 | 6.07e-01 |
| APOPTOTIC EXECUTION PHASE | 45 | 5.37e-01 | 5.32e-02 | 7.34e-01 |
| MITOCHONDRIAL TRANSLATION | 93 | 3.77e-01 | 5.31e-02 | 6.07e-01 |
| PROCESSIVE SYNTHESIS ON THE LAGGING STRAND | 15 | 7.23e-01 | 5.28e-02 | 8.67e-01 |
| UCH PROTEINASES | 90 | 3.87e-01 | 5.28e-02 | 6.12e-01 |
| PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR | 21 | 6.75e-01 | -5.28e-02 | 8.33e-01 |
| SIGNALING BY FGFR2 | 63 | 4.73e-01 | 5.23e-02 | 6.80e-01 |
| NUCLEAR ENVELOPE BREAKDOWN | 49 | 5.28e-01 | 5.21e-02 | 7.26e-01 |
| G2 M DNA DAMAGE CHECKPOINT | 69 | 4.56e-01 | -5.19e-02 | 6.70e-01 |
| FREE FATTY ACIDS REGULATE INSULIN SECRETION | 10 | 7.77e-01 | 5.18e-02 | 8.95e-01 |
| THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION | 14 | 7.39e-01 | 5.13e-02 | 8.68e-01 |
| INACTIVATION OF CSF3 G CSF SIGNALING | 24 | 6.64e-01 | 5.12e-02 | 8.25e-01 |
| TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS | 11 | 7.70e-01 | 5.10e-02 | 8.89e-01 |
| CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | 92 | 3.98e-01 | 5.10e-02 | 6.24e-01 |
| REGULATION OF TP53 ACTIVITY THROUGH METHYLATION | 18 | 7.08e-01 | -5.09e-02 | 8.58e-01 |
| REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION | 88 | 4.11e-01 | -5.08e-02 | 6.28e-01 |
| TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA | 34 | 6.10e-01 | 5.06e-02 | 7.93e-01 |
| TRIGLYCERIDE BIOSYNTHESIS | 10 | 7.82e-01 | -5.05e-02 | 8.98e-01 |
| MET PROMOTES CELL MOTILITY | 39 | 5.87e-01 | -5.03e-02 | 7.75e-01 |
| COMPLEMENT CASCADE | 26 | 6.62e-01 | 4.95e-02 | 8.23e-01 |
| TOLL LIKE RECEPTOR 9 TLR9 CASCADE | 91 | 4.17e-01 | 4.93e-02 | 6.35e-01 |
| EFFECTS OF PIP2 HYDROLYSIS | 27 | 6.58e-01 | -4.92e-02 | 8.21e-01 |
| TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS | 41 | 5.86e-01 | 4.91e-02 | 7.75e-01 |
| MRNA SPLICING | 188 | 2.49e-01 | 4.88e-02 | 4.90e-01 |
| REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | 83 | 4.42e-01 | 4.88e-02 | 6.58e-01 |
| NCAM SIGNALING FOR NEURITE OUT GROWTH | 62 | 5.07e-01 | -4.87e-02 | 7.10e-01 |
| EUKARYOTIC TRANSLATION INITIATION | 115 | 3.68e-01 | -4.87e-02 | 6.06e-01 |
| PI3K AKT SIGNALING IN CANCER | 91 | 4.23e-01 | 4.86e-02 | 6.42e-01 |
| IRF3 MEDIATED INDUCTION OF TYPE I IFN | 11 | 7.82e-01 | 4.82e-02 | 8.98e-01 |
| INCRETIN SYNTHESIS SECRETION AND INACTIVATION | 14 | 7.56e-01 | 4.79e-02 | 8.78e-01 |
| RHOC GTPASE CYCLE | 73 | 4.80e-01 | 4.78e-02 | 6.84e-01 |
| REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | 29 | 6.58e-01 | -4.75e-02 | 8.21e-01 |
| CYTOPROTECTION BY HMOX1 | 119 | 3.72e-01 | 4.75e-02 | 6.07e-01 |
| SURFACTANT METABOLISM | 16 | 7.43e-01 | 4.74e-02 | 8.70e-01 |
| TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | 83 | 4.60e-01 | 4.70e-02 | 6.74e-01 |
| VISUAL PHOTOTRANSDUCTION | 62 | 5.23e-01 | 4.69e-02 | 7.20e-01 |
| FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX | 50 | 5.73e-01 | -4.60e-02 | 7.62e-01 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 | 20 | 7.22e-01 | 4.60e-02 | 8.67e-01 |
| REGULATION OF LIPID METABOLISM BY PPARALPHA | 108 | 4.11e-01 | -4.58e-02 | 6.28e-01 |
| BASIGIN INTERACTIONS | 22 | 7.12e-01 | 4.55e-02 | 8.61e-01 |
| ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE | 96 | 4.43e-01 | 4.54e-02 | 6.58e-01 |
| SUMOYLATION OF UBIQUITINYLATION PROTEINS | 37 | 6.34e-01 | -4.53e-02 | 8.03e-01 |
| RHO GTPASES ACTIVATE ROCKS | 19 | 7.33e-01 | -4.52e-02 | 8.68e-01 |
| ERBB2 REGULATES CELL MOTILITY | 14 | 7.71e-01 | 4.49e-02 | 8.90e-01 |
| SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | 107 | 4.23e-01 | -4.49e-02 | 6.42e-01 |
| REGULATION OF TP53 ACTIVITY | 152 | 3.41e-01 | 4.48e-02 | 5.84e-01 |
| EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS | 31 | 6.68e-01 | -4.46e-02 | 8.27e-01 |
| SLC TRANSPORTER DISORDERS | 76 | 5.03e-01 | 4.45e-02 | 7.06e-01 |
| NICOTINATE METABOLISM | 23 | 7.13e-01 | 4.44e-02 | 8.61e-01 |
| STIMULI SENSING CHANNELS | 76 | 5.09e-01 | -4.38e-02 | 7.10e-01 |
| RND1 GTPASE CYCLE | 38 | 6.43e-01 | 4.35e-02 | 8.10e-01 |
| ERK MAPK TARGETS | 22 | 7.27e-01 | 4.31e-02 | 8.67e-01 |
| TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS | 12 | 7.96e-01 | 4.30e-02 | 9.06e-01 |
| RHO GTPASES ACTIVATE PAKS | 21 | 7.34e-01 | 4.29e-02 | 8.68e-01 |
| SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS | 18 | 7.53e-01 | -4.28e-02 | 8.76e-01 |
| STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES | 14 | 7.82e-01 | 4.27e-02 | 8.98e-01 |
| SIGNALING BY ACTIVIN | 11 | 8.10e-01 | 4.19e-02 | 9.13e-01 |
| CELLULAR RESPONSE TO CHEMICAL STRESS | 150 | 3.77e-01 | 4.19e-02 | 6.07e-01 |
| SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL | 13 | 7.94e-01 | -4.18e-02 | 9.06e-01 |
| EARLY PHASE OF HIV LIFE CYCLE | 13 | 7.95e-01 | 4.16e-02 | 9.06e-01 |
| SIGNALING BY ERBB2 | 48 | 6.18e-01 | 4.16e-02 | 7.95e-01 |
| RHO GTPASE CYCLE | 423 | 1.45e-01 | 4.14e-02 | 3.59e-01 |
| EXTRACELLULAR MATRIX ORGANIZATION | 250 | 2.60e-01 | -4.14e-02 | 5.02e-01 |
| CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY | 23 | 7.34e-01 | -4.09e-02 | 8.68e-01 |
| BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS | 11 | 8.15e-01 | -4.08e-02 | 9.16e-01 |
| RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY | 25 | 7.25e-01 | -4.07e-02 | 8.67e-01 |
| TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX | 30 | 7.00e-01 | 4.06e-02 | 8.50e-01 |
| SIGNALING BY NOTCH1 | 75 | 5.47e-01 | 4.02e-02 | 7.40e-01 |
| MOLECULES ASSOCIATED WITH ELASTIC FIBRES | 33 | 6.91e-01 | -4.00e-02 | 8.43e-01 |
| ELASTIC FIBRE FORMATION | 38 | 6.72e-01 | -3.97e-02 | 8.32e-01 |
| RNA POLYMERASE II TRANSCRIBES SNRNA GENES | 74 | 5.62e-01 | 3.90e-02 | 7.55e-01 |
| NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING | 33 | 6.99e-01 | 3.89e-02 | 8.50e-01 |
| DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | 26 | 7.32e-01 | 3.89e-02 | 8.68e-01 |
| REGULATION OF BETA CELL DEVELOPMENT | 30 | 7.14e-01 | -3.87e-02 | 8.61e-01 |
| TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | 74 | 5.66e-01 | -3.86e-02 | 7.56e-01 |
| DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS | 50 | 6.39e-01 | -3.83e-02 | 8.06e-01 |
| LGI ADAM INTERACTIONS | 14 | 8.04e-01 | 3.83e-02 | 9.12e-01 |
| SMOOTH MUSCLE CONTRACTION | 33 | 7.08e-01 | -3.77e-02 | 8.57e-01 |
| VOLTAGE GATED POTASSIUM CHANNELS | 38 | 6.88e-01 | 3.77e-02 | 8.42e-01 |
| GLUCAGON TYPE LIGAND RECEPTORS | 26 | 7.39e-01 | 3.77e-02 | 8.68e-01 |
| CHROMOSOME MAINTENANCE | 106 | 5.04e-01 | -3.76e-02 | 7.08e-01 |
| MRNA CAPPING | 29 | 7.28e-01 | 3.74e-02 | 8.67e-01 |
| SIGNALING BY ERYTHROPOIETIN | 24 | 7.53e-01 | -3.70e-02 | 8.76e-01 |
| RIPK1 MEDIATED REGULATED NECROSIS | 25 | 7.49e-01 | 3.70e-02 | 8.73e-01 |
| SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER | 59 | 6.26e-01 | 3.67e-02 | 8.00e-01 |
| DEADENYLATION DEPENDENT MRNA DECAY | 55 | 6.39e-01 | -3.66e-02 | 8.06e-01 |
| ERBB2 ACTIVATES PTK6 SIGNALING | 11 | 8.34e-01 | -3.64e-02 | 9.22e-01 |
| DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | 13 | 8.20e-01 | -3.64e-02 | 9.17e-01 |
| SIGNALING BY MET | 74 | 5.90e-01 | 3.63e-02 | 7.76e-01 |
| POLYMERASE SWITCHING | 14 | 8.14e-01 | -3.62e-02 | 9.16e-01 |
| CROSSLINKING OF COLLAGEN FIBRILS | 15 | 8.09e-01 | -3.61e-02 | 9.13e-01 |
| NRAGE SIGNALS DEATH THROUGH JNK | 54 | 6.47e-01 | -3.60e-02 | 8.15e-01 |
| ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING | 10 | 8.44e-01 | -3.59e-02 | 9.24e-01 |
| SIGNALING BY LEPTIN | 10 | 8.45e-01 | -3.57e-02 | 9.24e-01 |
| REGULATION OF TLR BY ENDOGENOUS LIGAND | 13 | 8.24e-01 | 3.56e-02 | 9.20e-01 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 | 26 | 7.54e-01 | -3.54e-02 | 8.77e-01 |
| AMYLOID FIBER FORMATION | 62 | 6.31e-01 | -3.53e-02 | 8.02e-01 |
| GENERATION OF SECOND MESSENGER MOLECULES | 19 | 7.91e-01 | -3.51e-02 | 9.04e-01 |
| TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX | 11 | 8.41e-01 | 3.49e-02 | 9.24e-01 |
| PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | 237 | 3.58e-01 | 3.47e-02 | 6.00e-01 |
| SIGNALING BY PDGF | 56 | 6.53e-01 | -3.47e-02 | 8.18e-01 |
| DNA STRAND ELONGATION | 32 | 7.34e-01 | 3.47e-02 | 8.68e-01 |
| SIGNALING BY ERBB2 ECD MUTANTS | 16 | 8.11e-01 | -3.46e-02 | 9.13e-01 |
| FLT3 SIGNALING | 36 | 7.20e-01 | -3.46e-02 | 8.67e-01 |
| CELLULAR HEXOSE TRANSPORT | 12 | 8.36e-01 | 3.45e-02 | 9.22e-01 |
| SIGNALING BY FGFR2 IIIA TM | 19 | 7.95e-01 | -3.44e-02 | 9.06e-01 |
| INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS | 35 | 7.29e-01 | 3.39e-02 | 8.67e-01 |
| RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS | 87 | 5.85e-01 | 3.39e-02 | 7.75e-01 |
| METABOLISM OF AMINE DERIVED HORMONES | 10 | 8.53e-01 | 3.38e-02 | 9.29e-01 |
| RNA POLYMERASE I TRANSCRIPTION INITIATION | 47 | 6.89e-01 | -3.37e-02 | 8.43e-01 |
| ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | 73 | 6.20e-01 | -3.36e-02 | 7.96e-01 |
| MRNA SPLICING MINOR PATHWAY | 52 | 6.78e-01 | 3.33e-02 | 8.34e-01 |
| HCMV EARLY EVENTS | 84 | 6.02e-01 | 3.30e-02 | 7.83e-01 |
| SIGNALING BY NOTCH | 193 | 4.37e-01 | 3.25e-02 | 6.54e-01 |
| TELOMERE MAINTENANCE | 82 | 6.14e-01 | -3.22e-02 | 7.95e-01 |
| REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION | 30 | 7.61e-01 | 3.21e-02 | 8.81e-01 |
| DEGRADATION OF THE EXTRACELLULAR MATRIX | 110 | 5.64e-01 | -3.19e-02 | 7.55e-01 |
| NUCLEOTIDE EXCISION REPAIR | 110 | 5.64e-01 | 3.19e-02 | 7.55e-01 |
| HCMV LATE EVENTS | 69 | 6.50e-01 | -3.16e-02 | 8.15e-01 |
| RND2 GTPASE CYCLE | 39 | 7.39e-01 | 3.08e-02 | 8.68e-01 |
| CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA | 59 | 6.84e-01 | -3.06e-02 | 8.39e-01 |
| TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES | 37 | 7.48e-01 | -3.06e-02 | 8.73e-01 |
| HIV TRANSCRIPTION INITIATION | 45 | 7.24e-01 | -3.04e-02 | 8.67e-01 |
| MITOCHONDRIAL BIOGENESIS | 92 | 6.15e-01 | -3.03e-02 | 7.95e-01 |
| FCERI MEDIATED CA 2 MOBILIZATION | 26 | 7.91e-01 | 3.00e-02 | 9.04e-01 |
| RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES | 20 | 8.18e-01 | 2.97e-02 | 9.16e-01 |
| INSULIN RECEPTOR SIGNALLING CASCADE | 46 | 7.28e-01 | -2.97e-02 | 8.67e-01 |
| CA2 PATHWAY | 59 | 6.94e-01 | 2.96e-02 | 8.45e-01 |
| FORMATION OF FIBRIN CLOT CLOTTING CASCADE | 23 | 8.07e-01 | -2.95e-02 | 9.13e-01 |
| SIGNALING BY NUCLEAR RECEPTORS | 229 | 4.44e-01 | 2.94e-02 | 6.58e-01 |
| EXTENSION OF TELOMERES | 49 | 7.22e-01 | 2.94e-02 | 8.67e-01 |
| TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS | 48 | 7.26e-01 | -2.93e-02 | 8.67e-01 |
| NONHOMOLOGOUS END JOINING NHEJ | 46 | 7.32e-01 | -2.92e-02 | 8.68e-01 |
| APOPTOTIC FACTOR MEDIATED RESPONSE | 18 | 8.30e-01 | 2.92e-02 | 9.21e-01 |
| REGULATED NECROSIS | 46 | 7.35e-01 | 2.89e-02 | 8.68e-01 |
| ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | 24 | 8.08e-01 | 2.86e-02 | 9.13e-01 |
| OXIDATIVE STRESS INDUCED SENESCENCE | 82 | 6.56e-01 | -2.84e-02 | 8.21e-01 |
| SIGNALING BY KIT IN DISEASE | 20 | 8.27e-01 | 2.82e-02 | 9.21e-01 |
| G ALPHA 12 13 SIGNALLING EVENTS | 75 | 6.77e-01 | 2.78e-02 | 8.34e-01 |
| PREGNENOLONE BIOSYNTHESIS | 12 | 8.69e-01 | -2.75e-02 | 9.38e-01 |
| LAGGING STRAND SYNTHESIS | 20 | 8.34e-01 | -2.71e-02 | 9.22e-01 |
| SUMOYLATION OF TRANSCRIPTION FACTORS | 18 | 8.45e-01 | 2.66e-02 | 9.24e-01 |
| TRANSLESION SYNTHESIS BY POLH | 19 | 8.43e-01 | -2.63e-02 | 9.24e-01 |
| GRB2 EVENTS IN ERBB2 SIGNALING | 15 | 8.60e-01 | 2.62e-02 | 9.34e-01 |
| INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING | 41 | 7.76e-01 | 2.57e-02 | 8.94e-01 |
| TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE | 19 | 8.46e-01 | 2.57e-02 | 9.24e-01 |
| NEUREXINS AND NEUROLIGINS | 54 | 7.44e-01 | 2.56e-02 | 8.71e-01 |
| PROCESSING OF CAPPED INTRONLESS PRE MRNA | 28 | 8.17e-01 | -2.53e-02 | 9.16e-01 |
| RNA POLYMERASE III CHAIN ELONGATION | 18 | 8.53e-01 | -2.52e-02 | 9.29e-01 |
| DETOXIFICATION OF REACTIVE OXYGEN SPECIES | 32 | 8.09e-01 | 2.47e-02 | 9.13e-01 |
| CIRCADIAN CLOCK | 68 | 7.28e-01 | -2.44e-02 | 8.67e-01 |
| FRS MEDIATED FGFR1 SIGNALING | 18 | 8.58e-01 | 2.44e-02 | 9.32e-01 |
| SIGNALING BY FGFR1 IN DISEASE | 33 | 8.10e-01 | 2.41e-02 | 9.13e-01 |
| REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR | 10 | 8.95e-01 | -2.41e-02 | 9.46e-01 |
| RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION | 23 | 8.42e-01 | 2.41e-02 | 9.24e-01 |
| RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE | 26 | 8.32e-01 | -2.40e-02 | 9.22e-01 |
| METABOLISM OF RNA | 645 | 3.00e-01 | 2.40e-02 | 5.45e-01 |
| SIGNALING BY FGFR3 FUSIONS IN CANCER | 10 | 8.96e-01 | 2.40e-02 | 9.46e-01 |
| ION CHANNEL TRANSPORT | 143 | 6.24e-01 | 2.38e-02 | 7.98e-01 |
| CELLULAR RESPONSE TO STARVATION | 147 | 6.21e-01 | -2.36e-02 | 7.97e-01 |
| SIGNALING BY FGFR4 IN DISEASE | 11 | 8.94e-01 | 2.32e-02 | 9.46e-01 |
| P75NTR RECRUITS SIGNALLING COMPLEXES | 12 | 8.92e-01 | 2.26e-02 | 9.46e-01 |
| ACYL CHAIN REMODELLING OF PS | 14 | 8.84e-01 | 2.26e-02 | 9.45e-01 |
| ANTIMICROBIAL PEPTIDES | 15 | 8.82e-01 | 2.22e-02 | 9.45e-01 |
| TRANSCRIPTIONAL REGULATION BY VENTX | 35 | 8.21e-01 | -2.22e-02 | 9.17e-01 |
| DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA | 63 | 7.62e-01 | -2.21e-02 | 8.81e-01 |
| TELOMERE C STRAND LAGGING STRAND SYNTHESIS | 33 | 8.27e-01 | 2.20e-02 | 9.21e-01 |
| METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES | 20 | 8.65e-01 | 2.19e-02 | 9.37e-01 |
| NERVOUS SYSTEM DEVELOPMENT | 554 | 3.80e-01 | 2.19e-02 | 6.09e-01 |
| ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION | 14 | 8.88e-01 | 2.18e-02 | 9.46e-01 |
| SIGNALING BY NTRK3 TRKC | 17 | 8.77e-01 | -2.16e-02 | 9.44e-01 |
| ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | 33 | 8.30e-01 | -2.16e-02 | 9.21e-01 |
| FRS MEDIATED FGFR2 SIGNALING | 19 | 8.70e-01 | -2.16e-02 | 9.39e-01 |
| ACETYLCHOLINE REGULATES INSULIN SECRETION | 10 | 9.09e-01 | -2.09e-02 | 9.52e-01 |
| RHOQ GTPASE CYCLE | 58 | 7.85e-01 | 2.07e-02 | 8.99e-01 |
| FORMATION OF THE EARLY ELONGATION COMPLEX | 33 | 8.37e-01 | 2.06e-02 | 9.22e-01 |
| CDC42 GTPASE CYCLE | 153 | 6.62e-01 | -2.05e-02 | 8.23e-01 |
| RNA POLYMERASE II TRANSCRIPTION | 1098 | 2.56e-01 | -2.04e-02 | 5.00e-01 |
| P75 NTR RECEPTOR MEDIATED SIGNALLING | 93 | 7.36e-01 | 2.02e-02 | 8.68e-01 |
| PLATELET HOMEOSTASIS | 78 | 7.58e-01 | 2.02e-02 | 8.79e-01 |
| IRAK1 RECRUITS IKK COMPLEX | 14 | 8.97e-01 | 2.00e-02 | 9.47e-01 |
| PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE | 19 | 8.81e-01 | -1.98e-02 | 9.45e-01 |
| RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES | 78 | 7.63e-01 | 1.97e-02 | 8.82e-01 |
| SUMOYLATION OF SUMOYLATION PROTEINS | 33 | 8.47e-01 | -1.94e-02 | 9.24e-01 |
| PYROPTOSIS | 21 | 8.80e-01 | 1.91e-02 | 9.45e-01 |
| ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS | 17 | 8.92e-01 | 1.90e-02 | 9.46e-01 |
| NETRIN 1 SIGNALING | 50 | 8.17e-01 | 1.90e-02 | 9.16e-01 |
| THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT | 172 | 6.74e-01 | 1.86e-02 | 8.33e-01 |
| RNA POLYMERASE II TRANSCRIPTION TERMINATION | 65 | 8.00e-01 | -1.82e-02 | 9.08e-01 |
| DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE | 48 | 8.28e-01 | -1.81e-02 | 9.21e-01 |
| CARNITINE METABOLISM | 14 | 9.07e-01 | -1.79e-02 | 9.52e-01 |
| TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | 79 | 7.83e-01 | 1.79e-02 | 8.99e-01 |
| SNRNP ASSEMBLY | 51 | 8.25e-01 | 1.79e-02 | 9.21e-01 |
| NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 48 | 8.33e-01 | -1.76e-02 | 9.22e-01 |
| CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | 72 | 7.98e-01 | -1.75e-02 | 9.06e-01 |
| SIGNALING BY EGFR IN CANCER | 22 | 8.88e-01 | 1.74e-02 | 9.46e-01 |
| TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX | 15 | 9.10e-01 | -1.68e-02 | 9.52e-01 |
| NOD1 2 SIGNALING PATHWAY | 35 | 8.65e-01 | 1.66e-02 | 9.37e-01 |
| SIGNALING BY ERBB2 IN CANCER | 25 | 8.87e-01 | 1.65e-02 | 9.46e-01 |
| DAP12 SIGNALING | 24 | 8.90e-01 | -1.63e-02 | 9.46e-01 |
| ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT | 23 | 8.93e-01 | -1.62e-02 | 9.46e-01 |
| RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER | 28 | 8.83e-01 | -1.60e-02 | 9.45e-01 |
| CAMK IV MEDIATED PHOSPHORYLATION OF CREB | 10 | 9.32e-01 | -1.57e-02 | 9.64e-01 |
| NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS | 53 | 8.48e-01 | -1.53e-02 | 9.24e-01 |
| CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS | 19 | 9.09e-01 | -1.52e-02 | 9.52e-01 |
| HIV TRANSCRIPTION ELONGATION | 42 | 8.66e-01 | -1.50e-02 | 9.37e-01 |
| SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP | 67 | 8.35e-01 | -1.47e-02 | 9.22e-01 |
| SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA | 41 | 8.72e-01 | -1.45e-02 | 9.40e-01 |
| MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS | 18 | 9.15e-01 | -1.45e-02 | 9.56e-01 |
| SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | 16 | 9.23e-01 | 1.39e-02 | 9.60e-01 |
| IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX | 10 | 9.40e-01 | -1.36e-02 | 9.70e-01 |
| FGFR2 ALTERNATIVE SPLICING | 25 | 9.07e-01 | 1.36e-02 | 9.52e-01 |
| SEMA4D IN SEMAPHORIN SIGNALING | 24 | 9.09e-01 | -1.35e-02 | 9.52e-01 |
| NUCLEAR PORE COMPLEX NPC DISASSEMBLY | 32 | 8.95e-01 | -1.35e-02 | 9.46e-01 |
| TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER | 78 | 8.37e-01 | 1.35e-02 | 9.22e-01 |
| ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS | 18 | 9.21e-01 | 1.34e-02 | 9.59e-01 |
| SYNDECAN INTERACTIONS | 27 | 9.07e-01 | 1.30e-02 | 9.52e-01 |
| SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS | 11 | 9.41e-01 | 1.29e-02 | 9.70e-01 |
| SIGNALING BY FGFR IN DISEASE | 57 | 8.67e-01 | -1.28e-02 | 9.37e-01 |
| DCC MEDIATED ATTRACTIVE SIGNALING | 14 | 9.34e-01 | 1.28e-02 | 9.65e-01 |
| SHC MEDIATED CASCADE FGFR1 | 16 | 9.31e-01 | -1.25e-02 | 9.64e-01 |
| DOWNREGULATION OF ERBB2 SIGNALING | 28 | 9.09e-01 | -1.24e-02 | 9.52e-01 |
| AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS | 10 | 9.48e-01 | 1.19e-02 | 9.75e-01 |
| FGFR1 MUTANT RECEPTOR ACTIVATION | 26 | 9.19e-01 | 1.15e-02 | 9.59e-01 |
| TP53 REGULATES METABOLIC GENES | 85 | 8.55e-01 | -1.15e-02 | 9.30e-01 |
| NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | 13 | 9.43e-01 | -1.14e-02 | 9.71e-01 |
| ION HOMEOSTASIS | 50 | 8.91e-01 | -1.12e-02 | 9.46e-01 |
| SIGNALING BY ROBO RECEPTORS | 208 | 7.85e-01 | 1.10e-02 | 8.99e-01 |
| PERK REGULATES GENE EXPRESSION | 28 | 9.20e-01 | 1.09e-02 | 9.59e-01 |
| YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | 12 | 9.49e-01 | -1.07e-02 | 9.75e-01 |
| METALLOPROTEASE DUBS | 27 | 9.25e-01 | 1.05e-02 | 9.61e-01 |
| RHOB GTPASE CYCLE | 67 | 8.83e-01 | 1.04e-02 | 9.45e-01 |
| CONSTITUTIVE SIGNALING BY EGFRVIII | 15 | 9.46e-01 | -1.01e-02 | 9.73e-01 |
| TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | 32 | 9.22e-01 | 1.01e-02 | 9.59e-01 |
| RAC1 GTPASE CYCLE | 177 | 8.18e-01 | 1.00e-02 | 9.16e-01 |
| DNA DOUBLE STRAND BREAK RESPONSE | 55 | 8.98e-01 | 1.00e-02 | 9.47e-01 |
| TRANSCRIPTION OF THE HIV GENOME | 67 | 8.91e-01 | 9.69e-03 | 9.46e-01 |
| SENSORY PROCESSING OF SOUND | 62 | 9.03e-01 | -8.96e-03 | 9.51e-01 |
| SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | 31 | 9.32e-01 | -8.82e-03 | 9.64e-01 |
| ESR MEDIATED SIGNALING | 172 | 8.44e-01 | 8.70e-03 | 9.24e-01 |
| ARACHIDONIC ACID METABOLISM | 38 | 9.26e-01 | 8.67e-03 | 9.61e-01 |
| TRNA PROCESSING | 105 | 8.78e-01 | 8.64e-03 | 9.44e-01 |
| SUMOYLATION OF RNA BINDING PROTEINS | 45 | 9.28e-01 | -7.79e-03 | 9.62e-01 |
| REGULATION OF EXPRESSION OF SLITS AND ROBOS | 163 | 8.67e-01 | -7.62e-03 | 9.37e-01 |
| SIGNALING BY TGF BETA RECEPTOR COMPLEX | 72 | 9.16e-01 | 7.20e-03 | 9.56e-01 |
| CYTOKINE SIGNALING IN IMMUNE SYSTEM | 542 | 7.98e-01 | -6.45e-03 | 9.06e-01 |
| SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 | 13 | 9.71e-01 | 5.86e-03 | 9.90e-01 |
| RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX | 29 | 9.57e-01 | -5.75e-03 | 9.81e-01 |
| DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | 23 | 9.63e-01 | 5.54e-03 | 9.85e-01 |
| P75NTR SIGNALS VIA NF KB | 15 | 9.72e-01 | -5.20e-03 | 9.91e-01 |
| REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION | 85 | 9.38e-01 | 4.88e-03 | 9.68e-01 |
| TRANSCRIPTIONAL REGULATION BY TP53 | 343 | 8.78e-01 | 4.83e-03 | 9.44e-01 |
| SIGNALING BY PDGFR IN DISEASE | 20 | 9.70e-01 | -4.81e-03 | 9.90e-01 |
| FORMATION OF RNA POL II ELONGATION COMPLEX | 57 | 9.50e-01 | -4.77e-03 | 9.75e-01 |
| RHO GTPASES ACTIVATE PKNS | 51 | 9.56e-01 | 4.50e-03 | 9.80e-01 |
| DEVELOPMENTAL BIOLOGY | 833 | 8.30e-01 | 4.40e-03 | 9.21e-01 |
| SIGNALLING TO RAS | 19 | 9.76e-01 | 4.02e-03 | 9.93e-01 |
| ELEVATION OF CYTOSOLIC CA2 LEVELS | 14 | 9.81e-01 | 3.65e-03 | 9.94e-01 |
| INTERLEUKIN RECEPTOR SHC SIGNALING | 20 | 9.78e-01 | 3.49e-03 | 9.94e-01 |
| PROCESSING OF INTRONLESS PRE MRNAS | 19 | 9.80e-01 | -3.40e-03 | 9.94e-01 |
| DISEASES OF PROGRAMMED CELL DEATH | 58 | 9.65e-01 | -3.31e-03 | 9.86e-01 |
| ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 9.82e-01 | 3.23e-03 | 9.94e-01 |
| AURKA ACTIVATION BY TPX2 | 71 | 9.63e-01 | -3.20e-03 | 9.85e-01 |
| INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | 34 | 9.76e-01 | 2.94e-03 | 9.93e-01 |
| MISMATCH REPAIR | 15 | 9.85e-01 | -2.81e-03 | 9.95e-01 |
| RIP MEDIATED NFKB ACTIVATION VIA ZBP1 | 15 | 9.87e-01 | -2.49e-03 | 9.95e-01 |
| NUCLEAR IMPORT OF REV PROTEIN | 32 | 9.82e-01 | 2.32e-03 | 9.94e-01 |
| UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION | 21 | 9.86e-01 | 2.26e-03 | 9.95e-01 |
| RUNX2 REGULATES BONE DEVELOPMENT | 29 | 9.87e-01 | -1.70e-03 | 9.95e-01 |
| PECAM1 INTERACTIONS | 12 | 9.92e-01 | 1.67e-03 | 9.99e-01 |
| RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 59 | 9.82e-01 | 1.66e-03 | 9.94e-01 |
| ION TRANSPORT BY P TYPE ATPASES | 50 | 9.87e-01 | -1.30e-03 | 9.95e-01 |
| REPRESSION OF WNT TARGET GENES | 14 | 9.94e-01 | -1.11e-03 | 1.00e+00 |
| PYRIMIDINE CATABOLISM | 10 | 9.96e-01 | 9.67e-04 | 1.00e+00 |
| CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER | 64 | 9.95e-01 | -4.21e-04 | 1.00e+00 |
| ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS | 26 | 9.98e-01 | -2.54e-04 | 1.00e+00 |
| PLASMA LIPOPROTEIN REMODELING | 14 | 9.99e-01 | -2.28e-04 | 1.00e+00 |
| SIGNALING BY NOTCH3 | 48 | 9.98e-01 | -1.71e-04 | 1.00e+00 |
| CELLULAR SENESCENCE | 146 | 9.99e-01 | 7.14e-05 | 1.00e+00 |
| SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | 14 | 1.00e+00 | -2.44e-05 | 1.00e+00 |
Detailed Gene set reports
FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC
| set | FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC |
| setSize | 19 |
| pANOVA | 9.3e-08 |
| s.dist | 0.707 |
| p.adjustANOVA | 5.48e-06 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Cct6a | 8139 |
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Tubb4b | 7623 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Cct5 | 7329 |
| Tuba4a | 7209 |
| Cct3 | 7151 |
| Tuba1a | 7068 |
| Tcp1 | 6640 |
| Cct8 | 6487 |
| Cct4 | 6253 |
| Tubb3 | 5844 |
| Cct7 | 4844 |
| Tuba1c | 4486 |
| Cct2 | 3834 |
| Tubb6 | 1808 |
| Tuba8 | -5580 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Cct6a | 8139 |
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Tubb4b | 7623 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Cct5 | 7329 |
| Tuba4a | 7209 |
| Cct3 | 7151 |
| Tuba1a | 7068 |
| Tcp1 | 6640 |
| Cct8 | 6487 |
| Cct4 | 6253 |
| Tubb3 | 5844 |
| Cct7 | 4844 |
| Tuba1c | 4486 |
| Cct2 | 3834 |
| Tubb6 | 1808 |
| Tuba8 | -5580 |
ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM
| set | ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM |
| setSize | 12 |
| pANOVA | 0.000263 |
| s.dist | 0.608 |
| p.adjustANOVA | 0.00399 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Fads2 | 8315 |
| Fads1 | 8229 |
| Elovl1 | 7474 |
| Hsd17b4 | 6569 |
| Acox1 | 6068 |
| Acaa1a | 5293 |
| Scp2 | 3813 |
| Acot8 | 3546 |
| Acsl1 | 2718 |
| Elovl5 | 2635 |
| Elovl2 | 2616 |
| Abcd1 | 1867 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Fads2 | 8315 |
| Fads1 | 8229 |
| Elovl1 | 7474 |
| Hsd17b4 | 6569 |
| Acox1 | 6068 |
| Acaa1a | 5293 |
| Scp2 | 3813 |
| Acot8 | 3546 |
| Acsl1 | 2718 |
| Elovl5 | 2635 |
| Elovl2 | 2616 |
| Abcd1 | 1867 |
GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION
| set | GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION |
| setSize | 12 |
| pANOVA | 0.000567 |
| s.dist | 0.575 |
| p.adjustANOVA | 0.00703 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Mapk3 | 7701 |
| Gorasp2 | 7541 |
| Mapk1 | 7098 |
| Uso1 | 6854 |
| Rab2a | 6471 |
| Rab1b | 6317 |
| Rab1a | 6147 |
| Ccnb2 | 5893 |
| Blzf1 | 4986 |
| Gorasp1 | 4113 |
| Golga2 | -3178 |
| Plk1 | -4346 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Mapk3 | 7701 |
| Gorasp2 | 7541 |
| Mapk1 | 7098 |
| Uso1 | 6854 |
| Rab2a | 6471 |
| Rab1b | 6317 |
| Rab1a | 6147 |
| Ccnb2 | 5893 |
| Blzf1 | 4986 |
| Gorasp1 | 4113 |
| Golga2 | -3178 |
| Plk1 | -4346 |
PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS
| set | PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS |
| setSize | 12 |
| pANOVA | 0.000787 |
| s.dist | 0.56 |
| p.adjustANOVA | 0.00909 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Impdh2 | 7592 |
| Gart | 7384 |
| Paics | 7072 |
| Adss | 6928 |
| Gmps | 6785 |
| Atic | 6716 |
| Adsl | 5425 |
| Adssl1 | 5348 |
| Impdh1 | 3127 |
| Ppat | 1919 |
| Lhpp | 1164 |
| Pfas | -5440 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Impdh2 | 7592 |
| Gart | 7384 |
| Paics | 7072 |
| Adss | 6928 |
| Gmps | 6785 |
| Atic | 6716 |
| Adsl | 5425 |
| Adssl1 | 5348 |
| Impdh1 | 3127 |
| Ppat | 1919 |
| Lhpp | 1164 |
| Pfas | -5440 |
RHOBTB3 ATPASE CYCLE
| set | RHOBTB3 ATPASE CYCLE |
| setSize | 10 |
| pANOVA | 0.00244 |
| s.dist | 0.553 |
| p.adjustANOVA | 0.0211 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Htr7 | 7894 |
| Ccne1 | 7432 |
| Rab9b | 5926 |
| Cul3 | 5824 |
| Hgs | 5342 |
| Plin3 | 5267 |
| Lrrc41 | 4587 |
| Vhl | 2256 |
| Rhobtb3 | 402 |
| Rab9 | -457 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Htr7 | 7894 |
| Ccne1 | 7432 |
| Rab9b | 5926 |
| Cul3 | 5824 |
| Hgs | 5342 |
| Plin3 | 5267 |
| Lrrc41 | 4587 |
| Vhl | 2256 |
| Rhobtb3 | 402 |
| Rab9 | -457 |
TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE
| set | TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE |
| setSize | 13 |
| pANOVA | 0.000834 |
| s.dist | 0.535 |
| p.adjustANOVA | 0.00936 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Tubb4b | 7623 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Tuba4a | 7209 |
| Tuba1a | 7068 |
| Tubb3 | 5844 |
| Gja1 | 5107 |
| Tuba1c | 4486 |
| Tubb6 | 1808 |
| Tuba8 | -5580 |
| Gjb2 | -8879 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Tubb4b | 7623 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Tuba4a | 7209 |
| Tuba1a | 7068 |
| Tubb3 | 5844 |
| Gja1 | 5107 |
| Tuba1c | 4486 |
| Tubb6 | 1808 |
| Tuba8 | -5580 |
| Gjb2 | -8879 |
BBSOME MEDIATED CARGO TARGETING TO CILIUM
| set | BBSOME MEDIATED CARGO TARGETING TO CILIUM |
| setSize | 23 |
| pANOVA | 9.26e-06 |
| s.dist | 0.534 |
| p.adjustANOVA | 0.00028 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Mkks | 8028 |
| Bbs10 | 7881 |
| Cct5 | 7329 |
| Mchr1 | 7256 |
| Bbs9 | 7235 |
| Cct3 | 7151 |
| Arl6 | 6977 |
| Tcp1 | 6640 |
| Lztfl1 | 6505 |
| Cct8 | 6487 |
| Cct4 | 6253 |
| Rab3ip | 6225 |
| Ttc8 | 6174 |
| Bbs1 | 5928 |
| Smo | 5055 |
| Bbs7 | 4517 |
| Cct2 | 3834 |
| Bbs2 | 2163 |
| Bbip1 | 1837 |
| Bbs4 | 1658 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Mkks | 8028 |
| Bbs10 | 7881 |
| Cct5 | 7329 |
| Mchr1 | 7256 |
| Bbs9 | 7235 |
| Cct3 | 7151 |
| Arl6 | 6977 |
| Tcp1 | 6640 |
| Lztfl1 | 6505 |
| Cct8 | 6487 |
| Cct4 | 6253 |
| Rab3ip | 6225 |
| Ttc8 | 6174 |
| Bbs1 | 5928 |
| Smo | 5055 |
| Bbs7 | 4517 |
| Cct2 | 3834 |
| Bbs2 | 2163 |
| Bbip1 | 1837 |
| Bbs4 | 1658 |
| Sstr3 | -5371 |
| Bbs5 | -5701 |
| Bbs12 | -5786 |
CITRIC ACID CYCLE TCA CYCLE
| set | CITRIC ACID CYCLE TCA CYCLE |
| setSize | 22 |
| pANOVA | 3.36e-05 |
| s.dist | 0.511 |
| p.adjustANOVA | 0.000817 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Idh2 | 8249 |
| Idh3a | 7988 |
| Fh1 | 7915 |
| Sucla2 | 6929 |
| Dld | 6907 |
| Idh3b | 6660 |
| Dlst | 6473 |
| Suclg2 | 5339 |
| Mdh2 | 5327 |
| Sdhd | 5081 |
| Aco2 | 4731 |
| Idh3g | 4299 |
| Sdha | 4005 |
| Cs | 3841 |
| Ogdh | 3658 |
| Suclg1 | 3556 |
| Sdhb | 2168 |
| Fahd1 | 1731 |
| Nnt | 1715 |
| Sdhc | 1199 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Idh2 | 8249 |
| Idh3a | 7988 |
| Fh1 | 7915 |
| Sucla2 | 6929 |
| Dld | 6907 |
| Idh3b | 6660 |
| Dlst | 6473 |
| Suclg2 | 5339 |
| Mdh2 | 5327 |
| Sdhd | 5081 |
| Aco2 | 4731 |
| Idh3g | 4299 |
| Sdha | 4005 |
| Cs | 3841 |
| Ogdh | 3658 |
| Suclg1 | 3556 |
| Sdhb | 2168 |
| Fahd1 | 1731 |
| Nnt | 1715 |
| Sdhc | 1199 |
| Me2 | -3410 |
| Me3 | -4850 |
NUCLEOBASE BIOSYNTHESIS
| set | NUCLEOBASE BIOSYNTHESIS |
| setSize | 15 |
| pANOVA | 0.000666 |
| s.dist | 0.507 |
| p.adjustANOVA | 0.00801 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Umps | 7689 |
| Impdh2 | 7592 |
| Gart | 7384 |
| Paics | 7072 |
| Adss | 6928 |
| Gmps | 6785 |
| Atic | 6716 |
| Adsl | 5425 |
| Adssl1 | 5348 |
| Impdh1 | 3127 |
| Ppat | 1919 |
| Lhpp | 1164 |
| Dhodh | 1011 |
| Cad | -2096 |
| Pfas | -5440 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Umps | 7689 |
| Impdh2 | 7592 |
| Gart | 7384 |
| Paics | 7072 |
| Adss | 6928 |
| Gmps | 6785 |
| Atic | 6716 |
| Adsl | 5425 |
| Adssl1 | 5348 |
| Impdh1 | 3127 |
| Ppat | 1919 |
| Lhpp | 1164 |
| Dhodh | 1011 |
| Cad | -2096 |
| Pfas | -5440 |
KERATAN SULFATE BIOSYNTHESIS
| set | KERATAN SULFATE BIOSYNTHESIS |
| setSize | 24 |
| pANOVA | 2.53e-05 |
| s.dist | 0.497 |
| p.adjustANOVA | 0.000648 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Prelp | 8307 |
| B4galt4 | 8133 |
| B4gat1 | 7867 |
| B4galt1 | 7207 |
| B4galt2 | 7054 |
| Chst2 | 6911 |
| B3gnt2 | 6457 |
| Chst1 | 5734 |
| St3gal4 | 5414 |
| Acan | 5263 |
| St3gal2 | 4805 |
| B4galt6 | 4182 |
| B3gnt4 | 4172 |
| Fmod | 4019 |
| Lum | 3387 |
| Slc35d2 | 3269 |
| B3gnt7 | 2823 |
| St3gal1 | 2426 |
| B4galt3 | 2032 |
| St3gal3 | 1873 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Prelp | 8307 |
| B4galt4 | 8133 |
| B4gat1 | 7867 |
| B4galt1 | 7207 |
| B4galt2 | 7054 |
| Chst2 | 6911 |
| B3gnt2 | 6457 |
| Chst1 | 5734 |
| St3gal4 | 5414 |
| Acan | 5263 |
| St3gal2 | 4805 |
| B4galt6 | 4182 |
| B3gnt4 | 4172 |
| Fmod | 4019 |
| Lum | 3387 |
| Slc35d2 | 3269 |
| B3gnt7 | 2823 |
| St3gal1 | 2426 |
| B4galt3 | 2032 |
| St3gal3 | 1873 |
| B4galt5 | 1638 |
| Chst5 | 1488 |
| Ogn | -1935 |
| St3gal6 | -7863 |
COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC
| set | COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC |
| setSize | 44 |
| pANOVA | 1.47e-08 |
| s.dist | 0.494 |
| p.adjustANOVA | 1.15e-06 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Capza2 | 7704 |
| Tubb4b | 7623 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Actr1a | 7390 |
| Capza1 | 7254 |
| Tuba4a | 7209 |
| Dctn4 | 7178 |
| Tuba1a | 7068 |
| Rab6a | 6582 |
| Rab18 | 6538 |
| Dctn6 | 6466 |
| Dctn1 | 6190 |
| Rab3gap1 | 6074 |
| Tubb3 | 5844 |
| Dync1i1 | 5761 |
| Pla2g6 | 5482 |
| Dctn5 | 5435 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Capza2 | 7704 |
| Tubb4b | 7623 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Actr1a | 7390 |
| Capza1 | 7254 |
| Tuba4a | 7209 |
| Dctn4 | 7178 |
| Tuba1a | 7068 |
| Rab6a | 6582 |
| Rab18 | 6538 |
| Dctn6 | 6466 |
| Dctn1 | 6190 |
| Rab3gap1 | 6074 |
| Tubb3 | 5844 |
| Dync1i1 | 5761 |
| Pla2g6 | 5482 |
| Dctn5 | 5435 |
| Rab6b | 5304 |
| Capzb | 5210 |
| Pla2g4a | 4648 |
| Tuba1c | 4486 |
| Galnt1 | 4232 |
| Dynll1 | 3614 |
| Dctn2 | 3316 |
| Actr10 | 2964 |
| Pafah1b3 | 2887 |
| Galnt2 | 2760 |
| Dync1li1 | 2626 |
| Pafah1b1 | 2587 |
| Pafah1b2 | 2295 |
| Rab3gap2 | 2194 |
| Agpat3 | 1988 |
| Tubb6 | 1808 |
| Dync1h1 | 1341 |
| Dctn3 | 330 |
| Bicd2 | -362 |
| Dynll2 | -1892 |
| Dync1li2 | -3544 |
| Dync1i2 | -3904 |
| Bicd1 | -4001 |
| Tuba8 | -5580 |
COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING
| set | COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING |
| setSize | 26 |
| pANOVA | 2.52e-05 |
| s.dist | 0.477 |
| p.adjustANOVA | 0.000648 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Cct6a | 8139 |
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Tubb4b | 7623 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Cct5 | 7329 |
| Tuba4a | 7209 |
| Cct3 | 7151 |
| Tuba1a | 7068 |
| Tcp1 | 6640 |
| Cct8 | 6487 |
| Cct4 | 6253 |
| Tubb3 | 5844 |
| Cct7 | 4844 |
| Pfdn4 | 4530 |
| Tuba1c | 4486 |
| Cct2 | 3834 |
| Vbp1 | 3178 |
| Tubb6 | 1808 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Cct6a | 8139 |
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Tubb4b | 7623 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Cct5 | 7329 |
| Tuba4a | 7209 |
| Cct3 | 7151 |
| Tuba1a | 7068 |
| Tcp1 | 6640 |
| Cct8 | 6487 |
| Cct4 | 6253 |
| Tubb3 | 5844 |
| Cct7 | 4844 |
| Pfdn4 | 4530 |
| Tuba1c | 4486 |
| Cct2 | 3834 |
| Vbp1 | 3178 |
| Tubb6 | 1808 |
| Pfdn1 | 575 |
| Pfdn5 | -3199 |
| Pfdn6 | -3811 |
| Pfdn2 | -4918 |
| Tuba8 | -5580 |
| Actb | -8390 |
HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR
| set | HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR |
| setSize | 48 |
| pANOVA | 2.45e-08 |
| s.dist | 0.465 |
| p.adjustANOVA | 1.7e-06 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Hspa2 | 8280 |
| Hspa1b | 8162 |
| Tubb2a | 8130 |
| Dnaja2 | 7983 |
| Tuba1b | 7873 |
| Capza2 | 7704 |
| Tubb4b | 7623 |
| Dnaja4 | 7557 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Actr1a | 7390 |
| Dnaja1 | 7328 |
| Capza1 | 7254 |
| Tuba4a | 7209 |
| Dctn4 | 7178 |
| Tuba1a | 7068 |
| Stip1 | 6833 |
| Dctn6 | 6466 |
| Dctn1 | 6190 |
| Fkbp5 | 5987 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Hspa2 | 8280 |
| Hspa1b | 8162 |
| Tubb2a | 8130 |
| Dnaja2 | 7983 |
| Tuba1b | 7873 |
| Capza2 | 7704 |
| Tubb4b | 7623 |
| Dnaja4 | 7557 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Actr1a | 7390 |
| Dnaja1 | 7328 |
| Capza1 | 7254 |
| Tuba4a | 7209 |
| Dctn4 | 7178 |
| Tuba1a | 7068 |
| Stip1 | 6833 |
| Dctn6 | 6466 |
| Dctn1 | 6190 |
| Fkbp5 | 5987 |
| Tubb3 | 5844 |
| Dync1i1 | 5761 |
| Fkbp4 | 5613 |
| Dctn5 | 5435 |
| Capzb | 5210 |
| Hspa8 | 5005 |
| Tuba1c | 4486 |
| Dynll1 | 3614 |
| Ptges3 | 3551 |
| Dctn2 | 3316 |
| Actr10 | 2964 |
| Dync1li1 | 2626 |
| Nr3c2 | 2403 |
| Tubb6 | 1808 |
| Dnajb1 | 1795 |
| Dync1h1 | 1341 |
| Dctn3 | 330 |
| Ar | 267 |
| Nr3c1 | -1010 |
| Dynll2 | -1892 |
| Hsp90ab1 | -2349 |
| Hspa1l | -2922 |
| Hsp90aa1 | -2972 |
| Pgr | -3541 |
| Dync1li2 | -3544 |
| Dync1i2 | -3904 |
| Hspa1a | -5095 |
| Tuba8 | -5580 |
KERATAN SULFATE KERATIN METABOLISM
| set | KERATAN SULFATE KERATIN METABOLISM |
| setSize | 30 |
| pANOVA | 1.45e-05 |
| s.dist | 0.457 |
| p.adjustANOVA | 0.000407 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Prelp | 8307 |
| B4galt4 | 8133 |
| B4gat1 | 7867 |
| B4galt1 | 7207 |
| B4galt2 | 7054 |
| Chst2 | 6911 |
| B3gnt2 | 6457 |
| Chst1 | 5734 |
| Hexa | 5634 |
| St3gal4 | 5414 |
| Acan | 5263 |
| St3gal2 | 4805 |
| Gns | 4657 |
| Hexb | 4302 |
| B4galt6 | 4182 |
| B3gnt4 | 4172 |
| Fmod | 4019 |
| Lum | 3387 |
| Slc35d2 | 3269 |
| B3gnt7 | 2823 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Prelp | 8307 |
| B4galt4 | 8133 |
| B4gat1 | 7867 |
| B4galt1 | 7207 |
| B4galt2 | 7054 |
| Chst2 | 6911 |
| B3gnt2 | 6457 |
| Chst1 | 5734 |
| Hexa | 5634 |
| St3gal4 | 5414 |
| Acan | 5263 |
| St3gal2 | 4805 |
| Gns | 4657 |
| Hexb | 4302 |
| B4galt6 | 4182 |
| B3gnt4 | 4172 |
| Fmod | 4019 |
| Lum | 3387 |
| Slc35d2 | 3269 |
| B3gnt7 | 2823 |
| St3gal1 | 2426 |
| Glb1 | 2203 |
| B4galt3 | 2032 |
| St3gal3 | 1873 |
| B4galt5 | 1638 |
| Chst5 | 1488 |
| Glb1l | 553 |
| Ogn | -1935 |
| Galns | -4082 |
| St3gal6 | -7863 |
CALNEXIN CALRETICULIN CYCLE
| set | CALNEXIN CALRETICULIN CYCLE |
| setSize | 26 |
| pANOVA | 5.88e-05 |
| s.dist | 0.455 |
| p.adjustANOVA | 0.00121 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Calr | 8220 |
| Derl2 | 8209 |
| Pdia3 | 7888 |
| Prkcsh | 7715 |
| Ganab | 7292 |
| Rnf185 | 6707 |
| Os9 | 6589 |
| Canx | 6366 |
| Man1b1 | 6136 |
| Marchf6 | 5841 |
| Rnf5 | 5663 |
| Edem2 | 5638 |
| Amfr | 5430 |
| Rnf139 | 5305 |
| Uggt1 | 5301 |
| Syvn1 | 5170 |
| Ubc | 4501 |
| Edem3 | 2272 |
| Ubb | 1303 |
| Rps27a | -478 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Calr | 8220 |
| Derl2 | 8209 |
| Pdia3 | 7888 |
| Prkcsh | 7715 |
| Ganab | 7292 |
| Rnf185 | 6707 |
| Os9 | 6589 |
| Canx | 6366 |
| Man1b1 | 6136 |
| Marchf6 | 5841 |
| Rnf5 | 5663 |
| Edem2 | 5638 |
| Amfr | 5430 |
| Rnf139 | 5305 |
| Uggt1 | 5301 |
| Syvn1 | 5170 |
| Ubc | 4501 |
| Edem3 | 2272 |
| Ubb | 1303 |
| Rps27a | -478 |
| Rnf103 | -722 |
| Edem1 | -1060 |
| Sel1l | -2257 |
| Uggt2 | -2740 |
| Trim13 | -3013 |
| Uba52 | -8214 |
GLYCOGEN STORAGE DISEASES
| set | GLYCOGEN STORAGE DISEASES |
| setSize | 12 |
| pANOVA | 0.00642 |
| s.dist | 0.454 |
| p.adjustANOVA | 0.0423 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Gyg | 7709 |
| Gaa | 7536 |
| Gbe1 | 7310 |
| Nhlrc1 | 6940 |
| G6pc3 | 6445 |
| Epm2a | 5097 |
| Ubc | 4501 |
| Ppp1r3c | 2881 |
| Gys1 | 1877 |
| Ubb | 1303 |
| Rps27a | -478 |
| Uba52 | -8214 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Gyg | 7709 |
| Gaa | 7536 |
| Gbe1 | 7310 |
| Nhlrc1 | 6940 |
| G6pc3 | 6445 |
| Epm2a | 5097 |
| Ubc | 4501 |
| Ppp1r3c | 2881 |
| Gys1 | 1877 |
| Ubb | 1303 |
| Rps27a | -478 |
| Uba52 | -8214 |
GAP JUNCTION ASSEMBLY
| set | GAP JUNCTION ASSEMBLY |
| setSize | 21 |
| pANOVA | 0.000313 |
| s.dist | 0.454 |
| p.adjustANOVA | 0.00461 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Tubb4b | 7623 |
| Gjb6 | 7578 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Tuba4a | 7209 |
| Tuba1a | 7068 |
| Gjd2 | 6954 |
| Gjd3 | 5960 |
| Tubb3 | 5844 |
| Gja1 | 5107 |
| Tuba1c | 4486 |
| Gjb1 | 3855 |
| Gjc1 | 2488 |
| Tubb6 | 1808 |
| Gjc2 | 1414 |
| Gja4 | -1333 |
| Tuba8 | -5580 |
| Gja5 | -7591 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Tubb4b | 7623 |
| Gjb6 | 7578 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Tuba4a | 7209 |
| Tuba1a | 7068 |
| Gjd2 | 6954 |
| Gjd3 | 5960 |
| Tubb3 | 5844 |
| Gja1 | 5107 |
| Tuba1c | 4486 |
| Gjb1 | 3855 |
| Gjc1 | 2488 |
| Tubb6 | 1808 |
| Gjc2 | 1414 |
| Gja4 | -1333 |
| Tuba8 | -5580 |
| Gja5 | -7591 |
| Gjb2 | -8879 |
ENDOSOMAL VACUOLAR PATHWAY
| set | ENDOSOMAL VACUOLAR PATHWAY |
| setSize | 10 |
| pANOVA | 0.0131 |
| s.dist | -0.453 |
| p.adjustANOVA | 0.0679 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| H2-T23 | -9189 |
| H2-M3 | -8825 |
| H2-Q7 | -7765 |
| B2m | -7134 |
| H2-Q10 | -6986 |
| H2-D1 | -5046 |
| Lnpep | -4289 |
| H2-Q2 | -2919 |
| Ctss | 2784 |
| Ctsl | 5337 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H2-T23 | -9189 |
| H2-M3 | -8825 |
| H2-Q7 | -7765 |
| B2m | -7134 |
| H2-Q10 | -6986 |
| H2-D1 | -5046 |
| Lnpep | -4289 |
| H2-Q2 | -2919 |
| Ctss | 2784 |
| Ctsl | 5337 |
RETROGRADE NEUROTROPHIN SIGNALLING
| set | RETROGRADE NEUROTROPHIN SIGNALLING |
| setSize | 13 |
| pANOVA | 0.00476 |
| s.dist | 0.452 |
| p.adjustANOVA | 0.0338 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Ap2m1 | 7792 |
| Dnm2 | 7615 |
| Ap2b1 | 7523 |
| Dnal4 | 7382 |
| Ap2a2 | 6985 |
| Ap2a1 | 6112 |
| Cltc | 4484 |
| Clta | 3557 |
| Sh3gl2 | 2858 |
| Dnm3 | 2300 |
| Dnm1 | 815 |
| Ap2s1 | -3478 |
| Ntrk1 | -7720 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Ap2m1 | 7792 |
| Dnm2 | 7615 |
| Ap2b1 | 7523 |
| Dnal4 | 7382 |
| Ap2a2 | 6985 |
| Ap2a1 | 6112 |
| Cltc | 4484 |
| Clta | 3557 |
| Sh3gl2 | 2858 |
| Dnm3 | 2300 |
| Dnm1 | 815 |
| Ap2s1 | -3478 |
| Ntrk1 | -7720 |
GLYCOGEN SYNTHESIS
| set | GLYCOGEN SYNTHESIS |
| setSize | 14 |
| pANOVA | 0.00362 |
| s.dist | 0.449 |
| p.adjustANOVA | 0.0273 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Pgm1 | 8318 |
| Ugp2 | 8093 |
| Gyg | 7709 |
| Gbe1 | 7310 |
| Nhlrc1 | 6940 |
| Pgm2 | 6645 |
| Epm2a | 5097 |
| Ubc | 4501 |
| Ppp1r3c | 2881 |
| Gys1 | 1877 |
| Ubb | 1303 |
| Rps27a | -478 |
| Pgm2l1 | -2580 |
| Uba52 | -8214 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Pgm1 | 8318 |
| Ugp2 | 8093 |
| Gyg | 7709 |
| Gbe1 | 7310 |
| Nhlrc1 | 6940 |
| Pgm2 | 6645 |
| Epm2a | 5097 |
| Ubc | 4501 |
| Ppp1r3c | 2881 |
| Gys1 | 1877 |
| Ubb | 1303 |
| Rps27a | -478 |
| Pgm2l1 | -2580 |
| Uba52 | -8214 |
SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III
| set | SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III |
| setSize | 23 |
| pANOVA | 0.000264 |
| s.dist | 0.439 |
| p.adjustANOVA | 0.00399 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Tubb4b | 7623 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Vps4a | 7253 |
| Tuba4a | 7209 |
| Chmp7 | 7152 |
| Chmp3 | 7108 |
| Tuba1a | 7068 |
| Chmp2b | 6347 |
| Chmp4b | 6043 |
| Spast | 5927 |
| Tubb3 | 5844 |
| Tuba1c | 4486 |
| Tubb6 | 1808 |
| Chmp6 | 1722 |
| Lemd2 | -1061 |
| Chmp2a | -2648 |
| Ist1 | -4380 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Tubb4b | 7623 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Vps4a | 7253 |
| Tuba4a | 7209 |
| Chmp7 | 7152 |
| Chmp3 | 7108 |
| Tuba1a | 7068 |
| Chmp2b | 6347 |
| Chmp4b | 6043 |
| Spast | 5927 |
| Tubb3 | 5844 |
| Tuba1c | 4486 |
| Tubb6 | 1808 |
| Chmp6 | 1722 |
| Lemd2 | -1061 |
| Chmp2a | -2648 |
| Ist1 | -4380 |
| Cc2d1b | -5271 |
| Tuba8 | -5580 |
| Chmp4c | -8521 |
LDL CLEARANCE
| set | LDL CLEARANCE |
| setSize | 16 |
| pANOVA | 0.00246 |
| s.dist | 0.437 |
| p.adjustANOVA | 0.0212 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Lipa | 8232 |
| Ap2m1 | 7792 |
| Ap2b1 | 7523 |
| Npc1 | 7222 |
| Ap2a2 | 6985 |
| Soat1 | 6715 |
| Ap2a1 | 6112 |
| Nceh1 | 5559 |
| Cltc | 4484 |
| Clta | 3557 |
| Ldlr | 1993 |
| Npc2 | 1628 |
| Lsr | 747 |
| Ap2s1 | -3478 |
| Pcsk9 | -4165 |
| Ldlrap1 | -6120 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Lipa | 8232 |
| Ap2m1 | 7792 |
| Ap2b1 | 7523 |
| Npc1 | 7222 |
| Ap2a2 | 6985 |
| Soat1 | 6715 |
| Ap2a1 | 6112 |
| Nceh1 | 5559 |
| Cltc | 4484 |
| Clta | 3557 |
| Ldlr | 1993 |
| Npc2 | 1628 |
| Lsr | 747 |
| Ap2s1 | -3478 |
| Pcsk9 | -4165 |
| Ldlrap1 | -6120 |
CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX
| set | CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX |
| setSize | 10 |
| pANOVA | 0.0169 |
| s.dist | 0.436 |
| p.adjustANOVA | 0.0796 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Sfn | 6247 |
| Chek1 | 6046 |
| Ywhaq | 5970 |
| Ywhab | 4892 |
| Ywhah | 3724 |
| Wee1 | 3718 |
| Ywhae | 2829 |
| Ywhaz | 1183 |
| Ywhag | 962 |
| Chek2 | -1401 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Sfn | 6247 |
| Chek1 | 6046 |
| Ywhaq | 5970 |
| Ywhab | 4892 |
| Ywhah | 3724 |
| Wee1 | 3718 |
| Ywhae | 2829 |
| Ywhaz | 1183 |
| Ywhag | 962 |
| Chek2 | -1401 |
OLFACTORY SIGNALING PATHWAY
| set | OLFACTORY SIGNALING PATHWAY |
| setSize | 40 |
| pANOVA | 2.55e-06 |
| s.dist | -0.43 |
| p.adjustANOVA | 0.000111 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Rtp4 | -9186 |
| Olfr981 | -9131 |
| Olfr354 | -9067 |
| Olfr635 | -8968 |
| Olfr1310 | -8892 |
| Olfr1192-ps1 | -8828 |
| Olfr796 | -8547 |
| Olfr1564 | -8513 |
| Olfr2 | -8472 |
| Olfr735 | -8412 |
| Olfr63 | -8335 |
| Olfr1309 | -8324 |
| Olfr986 | -8079 |
| Olfr287 | -7682 |
| Olfr90 | -7347 |
| Olfr78 | -7309 |
| Olfr31 | -6761 |
| Olfr804 | -6715 |
| Gng13 | -6625 |
| Olfr1385 | -6537 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Rtp4 | -9186 |
| Olfr981 | -9131 |
| Olfr354 | -9067 |
| Olfr635 | -8968 |
| Olfr1310 | -8892 |
| Olfr1192-ps1 | -8828 |
| Olfr796 | -8547 |
| Olfr1564 | -8513 |
| Olfr2 | -8472 |
| Olfr735 | -8412 |
| Olfr63 | -8335 |
| Olfr1309 | -8324 |
| Olfr986 | -8079 |
| Olfr287 | -7682 |
| Olfr90 | -7347 |
| Olfr78 | -7309 |
| Olfr31 | -6761 |
| Olfr804 | -6715 |
| Gng13 | -6625 |
| Olfr1385 | -6537 |
| Olfr161 | -5854 |
| Olfr365 | -5458 |
| Olfr137 | -5452 |
| Olfr713 | -5017 |
| Reep4 | -4433 |
| Olfr648 | -4385 |
| Olfr147 | -3213 |
| Olfr558 | -2467 |
| Olfr1507 | -587 |
| Reep6 | -581 |
| Reep3 | -347 |
| Olfr446 | 176 |
| Olfr95 | 314 |
| Olfr552 | 353 |
| Reep1 | 2408 |
| Gnal | 4240 |
| Reep2 | 5126 |
| Olfr464 | 6002 |
| Gnb1 | 6353 |
| Reep5 | 6885 |
RHO GTPASES ACTIVATE IQGAPS
| set | RHO GTPASES ACTIVATE IQGAPS |
| setSize | 23 |
| pANOVA | 0.00038 |
| s.dist | 0.428 |
| p.adjustANOVA | 0.0052 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Tubb4b | 7623 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Ctnna1 | 7490 |
| Tuba4a | 7209 |
| Tuba1a | 7068 |
| Ctnnb1 | 6811 |
| Men1 | 6235 |
| Rac1 | 6024 |
| Tubb3 | 5844 |
| Tuba1c | 4486 |
| Cdc42 | 3642 |
| Iqgap2 | 2148 |
| Actg1 | 1985 |
| Tubb6 | 1808 |
| Calm1 | 452 |
| Iqgap1 | -602 |
| Cdh1 | -3099 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Tubb4b | 7623 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Ctnna1 | 7490 |
| Tuba4a | 7209 |
| Tuba1a | 7068 |
| Ctnnb1 | 6811 |
| Men1 | 6235 |
| Rac1 | 6024 |
| Tubb3 | 5844 |
| Tuba1c | 4486 |
| Cdc42 | 3642 |
| Iqgap2 | 2148 |
| Actg1 | 1985 |
| Tubb6 | 1808 |
| Calm1 | 452 |
| Iqgap1 | -602 |
| Cdh1 | -3099 |
| Clip1 | -5315 |
| Tuba8 | -5580 |
| Actb | -8390 |
RECEPTOR MEDIATED MITOPHAGY
| set | RECEPTOR MEDIATED MITOPHAGY |
| setSize | 11 |
| pANOVA | 0.0148 |
| s.dist | 0.424 |
| p.adjustANOVA | 0.0747 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Fundc1 | 6710 |
| Atg12 | 6465 |
| Csnk2a2 | 5878 |
| Csnk2b | 5066 |
| Ulk1 | 4361 |
| Map1lc3b | 3537 |
| Src | 2554 |
| Pgam5 | 2246 |
| Atg5 | 1481 |
| Map1lc3a | 862 |
| Csnk2a1 | -2744 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Fundc1 | 6710 |
| Atg12 | 6465 |
| Csnk2a2 | 5878 |
| Csnk2b | 5066 |
| Ulk1 | 4361 |
| Map1lc3b | 3537 |
| Src | 2554 |
| Pgam5 | 2246 |
| Atg5 | 1481 |
| Map1lc3a | 862 |
| Csnk2a1 | -2744 |
PURINE SALVAGE
| set | PURINE SALVAGE |
| setSize | 12 |
| pANOVA | 0.0114 |
| s.dist | 0.422 |
| p.adjustANOVA | 0.0621 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Adk | 6835 |
| Pnp2 | 6410 |
| Gmpr2 | 6405 |
| Dck | 6352 |
| Dguok | 5002 |
| Hprt | 4961 |
| Gmpr | 3870 |
| Adal | 3168 |
| Ampd3 | 2031 |
| Ampd2 | 748 |
| Ada | -2928 |
| Aprt | -3371 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Adk | 6835 |
| Pnp2 | 6410 |
| Gmpr2 | 6405 |
| Dck | 6352 |
| Dguok | 5002 |
| Hprt | 4961 |
| Gmpr | 3870 |
| Adal | 3168 |
| Ampd3 | 2031 |
| Ampd2 | 748 |
| Ada | -2928 |
| Aprt | -3371 |
N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE
| set | N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE |
| setSize | 35 |
| pANOVA | 1.73e-05 |
| s.dist | 0.42 |
| p.adjustANOVA | 0.000474 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Calr | 8220 |
| Derl2 | 8209 |
| Pdia3 | 7888 |
| Ngly1 | 7717 |
| Prkcsh | 7715 |
| Mlec | 7563 |
| Vcp | 7409 |
| Ganab | 7292 |
| Rnf185 | 6707 |
| Os9 | 6589 |
| Derl1 | 6479 |
| Canx | 6366 |
| Man1b1 | 6136 |
| Marchf6 | 5841 |
| Rnf5 | 5663 |
| Edem2 | 5638 |
| Amfr | 5430 |
| Rnf139 | 5305 |
| Uggt1 | 5301 |
| Syvn1 | 5170 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Calr | 8220 |
| Derl2 | 8209 |
| Pdia3 | 7888 |
| Ngly1 | 7717 |
| Prkcsh | 7715 |
| Mlec | 7563 |
| Vcp | 7409 |
| Ganab | 7292 |
| Rnf185 | 6707 |
| Os9 | 6589 |
| Derl1 | 6479 |
| Canx | 6366 |
| Man1b1 | 6136 |
| Marchf6 | 5841 |
| Rnf5 | 5663 |
| Edem2 | 5638 |
| Amfr | 5430 |
| Rnf139 | 5305 |
| Uggt1 | 5301 |
| Syvn1 | 5170 |
| Ubc | 4501 |
| Rad23b | 3837 |
| Edem3 | 2272 |
| Ubb | 1303 |
| Psmc1 | 755 |
| Rps27a | -478 |
| Rnf103 | -722 |
| Edem1 | -1060 |
| Ubxn1 | -2036 |
| Sel1l | -2257 |
| Uggt2 | -2740 |
| Trim13 | -3013 |
| Mogs | -3454 |
| Engase | -7027 |
| Uba52 | -8214 |
CD28 DEPENDENT VAV1 PATHWAY
| set | CD28 DEPENDENT VAV1 PATHWAY |
| setSize | 11 |
| pANOVA | 0.0164 |
| s.dist | 0.418 |
| p.adjustANOVA | 0.0789 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Cd86 | 6436 |
| Pak1 | 6373 |
| Rac1 | 6024 |
| Pak2 | 5895 |
| Fyn | 4409 |
| Cdc42 | 3642 |
| Pak3 | 3585 |
| Lck | 3288 |
| Vav1 | 1300 |
| Grb2 | -450 |
| Cd80 | -4689 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Cd86 | 6436 |
| Pak1 | 6373 |
| Rac1 | 6024 |
| Pak2 | 5895 |
| Fyn | 4409 |
| Cdc42 | 3642 |
| Pak3 | 3585 |
| Lck | 3288 |
| Vav1 | 1300 |
| Grb2 | -450 |
| Cd80 | -4689 |
ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING
| set | ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING |
| setSize | 11 |
| pANOVA | 0.0165 |
| s.dist | 0.417 |
| p.adjustANOVA | 0.0789 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Prkcsh | 7715 |
| Capza2 | 7704 |
| Mapk3 | 7701 |
| Capza1 | 7254 |
| Mapk1 | 7098 |
| Ddost | 5929 |
| App | 5599 |
| Hmgb1 | -1491 |
| Ager | -2691 |
| Lgals3 | -3828 |
| S100b | -5235 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Prkcsh | 7715 |
| Capza2 | 7704 |
| Mapk3 | 7701 |
| Capza1 | 7254 |
| Mapk1 | 7098 |
| Ddost | 5929 |
| App | 5599 |
| Hmgb1 | -1491 |
| Ager | -2691 |
| Lgals3 | -3828 |
| S100b | -5235 |
N GLYCAN ANTENNAE ELONGATION
| set | N GLYCAN ANTENNAE ELONGATION |
| setSize | 15 |
| pANOVA | 0.00518 |
| s.dist | 0.417 |
| p.adjustANOVA | 0.0355 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| B4galt4 | 8133 |
| B4galt1 | 7207 |
| B4galt2 | 7054 |
| St8sia3 | 5896 |
| St3gal4 | 5414 |
| B4galt6 | 4182 |
| St8sia2 | 3412 |
| Mgat4b | 3298 |
| B4galt3 | 2032 |
| B4galt5 | 1638 |
| St8sia6 | 1391 |
| Mgat4c | 920 |
| Mgat4a | 5 |
| St6gal1 | -307 |
| Mgat5 | -1593 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| B4galt4 | 8133 |
| B4galt1 | 7207 |
| B4galt2 | 7054 |
| St8sia3 | 5896 |
| St3gal4 | 5414 |
| B4galt6 | 4182 |
| St8sia2 | 3412 |
| Mgat4b | 3298 |
| B4galt3 | 2032 |
| B4galt5 | 1638 |
| St8sia6 | 1391 |
| Mgat4c | 920 |
| Mgat4a | 5 |
| St6gal1 | -307 |
| Mgat5 | -1593 |
TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX
| set | TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX |
| setSize | 12 |
| pANOVA | 0.0124 |
| s.dist | 0.417 |
| p.adjustANOVA | 0.0653 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Chmp7 | 7152 |
| Chmp3 | 7108 |
| Chmp2b | 6347 |
| Becn1 | 6138 |
| Chmp4b | 6043 |
| Uvrag | 5914 |
| Pik3c3 | 3999 |
| Map1lc3b | 3537 |
| Pik3r4 | 2157 |
| Chmp6 | 1722 |
| Chmp2a | -2648 |
| Chmp4c | -8521 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Chmp7 | 7152 |
| Chmp3 | 7108 |
| Chmp2b | 6347 |
| Becn1 | 6138 |
| Chmp4b | 6043 |
| Uvrag | 5914 |
| Pik3c3 | 3999 |
| Map1lc3b | 3537 |
| Pik3r4 | 2157 |
| Chmp6 | 1722 |
| Chmp2a | -2648 |
| Chmp4c | -8521 |
WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2
| set | WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 |
| setSize | 13 |
| pANOVA | 0.00963 |
| s.dist | 0.415 |
| p.adjustANOVA | 0.0543 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Fzd2 | 8203 |
| Ap2m1 | 7792 |
| Ap2b1 | 7523 |
| Ap2a2 | 6985 |
| Fzd5 | 6689 |
| Ap2a1 | 6112 |
| Cltc | 4484 |
| Clta | 3557 |
| Ror2 | 3169 |
| Cltb | 3125 |
| Ap2s1 | -3478 |
| Wnt5a | -5647 |
| Ror1 | -6567 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Fzd2 | 8203 |
| Ap2m1 | 7792 |
| Ap2b1 | 7523 |
| Ap2a2 | 6985 |
| Fzd5 | 6689 |
| Ap2a1 | 6112 |
| Cltc | 4484 |
| Clta | 3557 |
| Ror2 | 3169 |
| Cltb | 3125 |
| Ap2s1 | -3478 |
| Wnt5a | -5647 |
| Ror1 | -6567 |
SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL
| set | SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL |
| setSize | 10 |
| pANOVA | 0.0235 |
| s.dist | 0.414 |
| p.adjustANOVA | 0.1 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Itpk1 | 7922 |
| Nudt11 | 7798 |
| Ip6k3 | 7088 |
| Nudt10 | 5335 |
| Nudt4 | 3965 |
| Ip6k1 | 2825 |
| Nudt3 | 2744 |
| Ippk | 611 |
| Ppip5k1 | -2556 |
| Ppip5k2 | -3537 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Itpk1 | 7922 |
| Nudt11 | 7798 |
| Ip6k3 | 7088 |
| Nudt10 | 5335 |
| Nudt4 | 3965 |
| Ip6k1 | 2825 |
| Nudt3 | 2744 |
| Ippk | 611 |
| Ppip5k1 | -2556 |
| Ppip5k2 | -3537 |
GLYCOGEN METABOLISM
| set | GLYCOGEN METABOLISM |
| setSize | 25 |
| pANOVA | 0.000352 |
| s.dist | 0.413 |
| p.adjustANOVA | 0.00499 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Pgm1 | 8318 |
| Ugp2 | 8093 |
| Gyg | 7709 |
| Gaa | 7536 |
| Pygb | 7373 |
| Gbe1 | 7310 |
| Nhlrc1 | 6940 |
| Pygm | 6867 |
| Pgm2 | 6645 |
| Phkb | 5294 |
| Epm2a | 5097 |
| Ubc | 4501 |
| Phka1 | 3671 |
| Ppp1r3c | 2881 |
| Gys1 | 1877 |
| Phkg1 | 1377 |
| Phkg2 | 1354 |
| Ubb | 1303 |
| Agl | 1035 |
| Calm1 | 452 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Pgm1 | 8318 |
| Ugp2 | 8093 |
| Gyg | 7709 |
| Gaa | 7536 |
| Pygb | 7373 |
| Gbe1 | 7310 |
| Nhlrc1 | 6940 |
| Pygm | 6867 |
| Pgm2 | 6645 |
| Phkb | 5294 |
| Epm2a | 5097 |
| Ubc | 4501 |
| Phka1 | 3671 |
| Ppp1r3c | 2881 |
| Gys1 | 1877 |
| Phkg1 | 1377 |
| Phkg2 | 1354 |
| Ubb | 1303 |
| Agl | 1035 |
| Calm1 | 452 |
| Rps27a | -478 |
| Phka2 | -1545 |
| Pgm2l1 | -2580 |
| Pygl | -2605 |
| Uba52 | -8214 |
REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS
| set | REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS |
| setSize | 14 |
| pANOVA | 0.00817 |
| s.dist | 0.408 |
| p.adjustANOVA | 0.0491 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Pou4f1 | 7924 |
| Banp | 7905 |
| Trp73 | 7773 |
| Ppp1r13b | 7716 |
| Pou4f2 | 5933 |
| Ppp1r13l | 4080 |
| Trp53 | 3772 |
| Akt1 | 2879 |
| Zfp385a | 2519 |
| Phf20 | 1128 |
| Akt3 | -553 |
| Akt2 | -868 |
| Trp53bp2 | -1465 |
| Trp63 | -4365 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Pou4f1 | 7924 |
| Banp | 7905 |
| Trp73 | 7773 |
| Ppp1r13b | 7716 |
| Pou4f2 | 5933 |
| Ppp1r13l | 4080 |
| Trp53 | 3772 |
| Akt1 | 2879 |
| Zfp385a | 2519 |
| Phf20 | 1128 |
| Akt3 | -553 |
| Akt2 | -868 |
| Trp53bp2 | -1465 |
| Trp63 | -4365 |
CYTOSOLIC TRNA AMINOACYLATION
| set | CYTOSOLIC TRNA AMINOACYLATION |
| setSize | 24 |
| pANOVA | 0.000541 |
| s.dist | 0.408 |
| p.adjustANOVA | 0.00692 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Hars | 8296 |
| Rars | 7471 |
| Aimp2 | 7423 |
| Farsb | 7201 |
| Ppa1 | 7101 |
| Eef1e1 | 6694 |
| Yars | 6614 |
| Mars1 | 6308 |
| Wars | 6256 |
| Aars | 5087 |
| Iars | 5038 |
| Qars | 4242 |
| Gars | 3842 |
| Dars | 3103 |
| Kars | 2797 |
| Nars | 1888 |
| Lars | 955 |
| Aimp1 | -438 |
| Tars | -1337 |
| Cars | -1855 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Hars | 8296 |
| Rars | 7471 |
| Aimp2 | 7423 |
| Farsb | 7201 |
| Ppa1 | 7101 |
| Eef1e1 | 6694 |
| Yars | 6614 |
| Mars1 | 6308 |
| Wars | 6256 |
| Aars | 5087 |
| Iars | 5038 |
| Qars | 4242 |
| Gars | 3842 |
| Dars | 3103 |
| Kars | 2797 |
| Nars | 1888 |
| Lars | 955 |
| Aimp1 | -438 |
| Tars | -1337 |
| Cars | -1855 |
| Sars | -2075 |
| Eprs | -2547 |
| Vars | -2870 |
| Farsa | -3229 |
INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE
| set | INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE |
| setSize | 22 |
| pANOVA | 0.000955 |
| s.dist | 0.407 |
| p.adjustANOVA | 0.0105 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Get1 | 8075 |
| Stx1a | 7269 |
| Prnp | 7172 |
| Get3 | 7134 |
| Bag6 | 5901 |
| App | 5599 |
| Ubl4a | 5383 |
| Sgta | 5141 |
| Cyb5a | 5085 |
| Vamp2 | 4706 |
| Emd | 4454 |
| Serp1 | 4345 |
| Vapa | 3070 |
| Sec61g | 2206 |
| Hmox1 | 1081 |
| Stx5a | 590 |
| Caml | 502 |
| Otof | -914 |
| Get4 | -946 |
| Sec61b | -1210 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Get1 | 8075 |
| Stx1a | 7269 |
| Prnp | 7172 |
| Get3 | 7134 |
| Bag6 | 5901 |
| App | 5599 |
| Ubl4a | 5383 |
| Sgta | 5141 |
| Cyb5a | 5085 |
| Vamp2 | 4706 |
| Emd | 4454 |
| Serp1 | 4345 |
| Vapa | 3070 |
| Sec61g | 2206 |
| Hmox1 | 1081 |
| Stx5a | 590 |
| Caml | 502 |
| Otof | -914 |
| Get4 | -946 |
| Sec61b | -1210 |
| Aldh3a2 | -2413 |
| Ube2j2 | -2806 |
GLYCOSPHINGOLIPID METABOLISM
| set | GLYCOSPHINGOLIPID METABOLISM |
| setSize | 38 |
| pANOVA | 1.44e-05 |
| s.dist | 0.407 |
| p.adjustANOVA | 0.000407 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| B3galnt1 | 8049 |
| B4galnt1 | 7752 |
| Ugt8a | 7449 |
| Galc | 7211 |
| Neu2 | 7013 |
| Smpd1 | 6879 |
| Gba2 | 6790 |
| Arsa | 6741 |
| Arsb | 6728 |
| Neu1 | 6713 |
| Asah1 | 6629 |
| Esyt1 | 6585 |
| Gltp | 6314 |
| Gm2a | 6088 |
| Neu4 | 5754 |
| Psap | 5642 |
| Hexa | 5634 |
| Gba | 5557 |
| Gla | 4913 |
| Hexb | 4302 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| B3galnt1 | 8049 |
| B4galnt1 | 7752 |
| Ugt8a | 7449 |
| Galc | 7211 |
| Neu2 | 7013 |
| Smpd1 | 6879 |
| Gba2 | 6790 |
| Arsa | 6741 |
| Arsb | 6728 |
| Neu1 | 6713 |
| Asah1 | 6629 |
| Esyt1 | 6585 |
| Gltp | 6314 |
| Gm2a | 6088 |
| Neu4 | 5754 |
| Psap | 5642 |
| Hexa | 5634 |
| Gba | 5557 |
| Gla | 4913 |
| Hexb | 4302 |
| Smpd3 | 4202 |
| Ugcg | 2968 |
| Neu3 | 2483 |
| Sumf1 | 2213 |
| Glb1 | 2203 |
| Sumf2 | 2178 |
| Arsk | 1771 |
| Glb1l | 553 |
| Esyt3 | -117 |
| Cptp | -918 |
| Smpd4 | -2132 |
| Ctsa | -2133 |
| Arsj | -2310 |
| Asah2 | -2428 |
| Smpd2 | -2821 |
| Arsg | -3313 |
| Cerk | -4545 |
| Esyt2 | -6873 |
WNT LIGAND BIOGENESIS AND TRAFFICKING
| set | WNT LIGAND BIOGENESIS AND TRAFFICKING |
| setSize | 21 |
| pANOVA | 0.00161 |
| s.dist | 0.398 |
| p.adjustANOVA | 0.0157 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Wnt11 | 8332 |
| Wls | 8074 |
| Wnt9b | 7249 |
| Snx3 | 7022 |
| Vps35 | 6714 |
| Vps26a | 4677 |
| Wnt7b | 4600 |
| Vps29 | 4573 |
| Wnt9a | 3779 |
| Wnt3 | 3485 |
| Wnt10a | 2481 |
| Wnt2b | 2461 |
| Wnt2 | 2442 |
| Wnt7a | 2248 |
| Wnt4 | 1512 |
| Wnt16 | 1065 |
| Porcn | 773 |
| Tmed5 | 170 |
| Wnt5b | 161 |
| Wnt6 | -1598 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Wnt11 | 8332 |
| Wls | 8074 |
| Wnt9b | 7249 |
| Snx3 | 7022 |
| Vps35 | 6714 |
| Vps26a | 4677 |
| Wnt7b | 4600 |
| Vps29 | 4573 |
| Wnt9a | 3779 |
| Wnt3 | 3485 |
| Wnt10a | 2481 |
| Wnt2b | 2461 |
| Wnt2 | 2442 |
| Wnt7a | 2248 |
| Wnt4 | 1512 |
| Wnt16 | 1065 |
| Porcn | 773 |
| Tmed5 | 170 |
| Wnt5b | 161 |
| Wnt6 | -1598 |
| Wnt5a | -5647 |
SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS
| set | SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS |
| setSize | 20 |
| pANOVA | 0.0021 |
| s.dist | 0.397 |
| p.adjustANOVA | 0.0191 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Acsl4 | 7747 |
| Acsbg1 | 7637 |
| Hsd17b12 | 7632 |
| Elovl1 | 7474 |
| Tecr | 7019 |
| Hacd2 | 6516 |
| Acsl6 | 6051 |
| Hacd3 | 5883 |
| Elovl4 | 5852 |
| Acsl5 | 4918 |
| Acsl3 | 4278 |
| Elovl6 | 2864 |
| Acsl1 | 2718 |
| Elovl5 | 2635 |
| Elovl2 | 2616 |
| Slc27a3 | 2121 |
| Acsf3 | -1821 |
| Hacd4 | -3876 |
| Elovl7 | -8098 |
| Hacd1 | -8737 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Acsl4 | 7747 |
| Acsbg1 | 7637 |
| Hsd17b12 | 7632 |
| Elovl1 | 7474 |
| Tecr | 7019 |
| Hacd2 | 6516 |
| Acsl6 | 6051 |
| Hacd3 | 5883 |
| Elovl4 | 5852 |
| Acsl5 | 4918 |
| Acsl3 | 4278 |
| Elovl6 | 2864 |
| Acsl1 | 2718 |
| Elovl5 | 2635 |
| Elovl2 | 2616 |
| Slc27a3 | 2121 |
| Acsf3 | -1821 |
| Hacd4 | -3876 |
| Elovl7 | -8098 |
| Hacd1 | -8737 |
GLYCOGEN BREAKDOWN GLYCOGENOLYSIS
| set | GLYCOGEN BREAKDOWN GLYCOGENOLYSIS |
| setSize | 14 |
| pANOVA | 0.0108 |
| s.dist | 0.394 |
| p.adjustANOVA | 0.0595 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Gyg | 7709 |
| Gaa | 7536 |
| Pygb | 7373 |
| Pygm | 6867 |
| Pgm2 | 6645 |
| Phkb | 5294 |
| Phka1 | 3671 |
| Phkg1 | 1377 |
| Phkg2 | 1354 |
| Agl | 1035 |
| Calm1 | 452 |
| Phka2 | -1545 |
| Pgm2l1 | -2580 |
| Pygl | -2605 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Gyg | 7709 |
| Gaa | 7536 |
| Pygb | 7373 |
| Pygm | 6867 |
| Pgm2 | 6645 |
| Phkb | 5294 |
| Phka1 | 3671 |
| Phkg1 | 1377 |
| Phkg2 | 1354 |
| Agl | 1035 |
| Calm1 | 452 |
| Phka2 | -1545 |
| Pgm2l1 | -2580 |
| Pygl | -2605 |
SUPPRESSION OF PHAGOSOMAL MATURATION
| set | SUPPRESSION OF PHAGOSOMAL MATURATION |
| setSize | 12 |
| pANOVA | 0.0183 |
| s.dist | 0.394 |
| p.adjustANOVA | 0.0837 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Rab5a | 7204 |
| Atp6v1h | 6960 |
| Rab7 | 5495 |
| Hgs | 5342 |
| Kpna1 | 5150 |
| Ubc | 4501 |
| Coro1a | 3189 |
| Kpnb1 | 3097 |
| Vps33b | 2937 |
| Ubb | 1303 |
| Rps27a | -478 |
| Uba52 | -8214 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Rab5a | 7204 |
| Atp6v1h | 6960 |
| Rab7 | 5495 |
| Hgs | 5342 |
| Kpna1 | 5150 |
| Ubc | 4501 |
| Coro1a | 3189 |
| Kpnb1 | 3097 |
| Vps33b | 2937 |
| Ubb | 1303 |
| Rps27a | -478 |
| Uba52 | -8214 |
CS DS DEGRADATION
| set | CS DS DEGRADATION |
| setSize | 14 |
| pANOVA | 0.0123 |
| s.dist | 0.386 |
| p.adjustANOVA | 0.0652 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Ids | 7282 |
| Arsb | 6728 |
| Vcan | 6690 |
| Bgn | 6561 |
| Hexa | 5634 |
| Cspg4 | 4948 |
| Bcan | 4795 |
| Cspg5 | 4633 |
| Hexb | 4302 |
| Hyal3 | 1785 |
| Hyal1 | -217 |
| Dcn | -2327 |
| Ncan | -3338 |
| Idua | -5811 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Ids | 7282 |
| Arsb | 6728 |
| Vcan | 6690 |
| Bgn | 6561 |
| Hexa | 5634 |
| Cspg4 | 4948 |
| Bcan | 4795 |
| Cspg5 | 4633 |
| Hexb | 4302 |
| Hyal3 | 1785 |
| Hyal1 | -217 |
| Dcn | -2327 |
| Ncan | -3338 |
| Idua | -5811 |
IRE1ALPHA ACTIVATES CHAPERONES
| set | IRE1ALPHA ACTIVATES CHAPERONES |
| setSize | 50 |
| pANOVA | 2.68e-06 |
| s.dist | 0.384 |
| p.adjustANOVA | 0.000112 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Tpp1 | 8361 |
| Pdia6 | 8350 |
| Dnajc3 | 8341 |
| Hspa5 | 8305 |
| Xbp1 | 8257 |
| Srprb | 7690 |
| Atp6v0d1 | 7590 |
| Dnajb11 | 7553 |
| Gfpt1 | 7056 |
| Dnajb9 | 7052 |
| Srpr | 6287 |
| Lmna | 6277 |
| Dctn1 | 6190 |
| Preb | 6173 |
| Hyou1 | 6158 |
| Kdelr3 | 6078 |
| Ppp2r5b | 5759 |
| Yif1a | 5617 |
| Ssr1 | 5265 |
| Cxxc1 | 5185 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Tpp1 | 8361 |
| Pdia6 | 8350 |
| Dnajc3 | 8341 |
| Hspa5 | 8305 |
| Xbp1 | 8257 |
| Srprb | 7690 |
| Atp6v0d1 | 7590 |
| Dnajb11 | 7553 |
| Gfpt1 | 7056 |
| Dnajb9 | 7052 |
| Srpr | 6287 |
| Lmna | 6277 |
| Dctn1 | 6190 |
| Preb | 6173 |
| Hyou1 | 6158 |
| Kdelr3 | 6078 |
| Ppp2r5b | 5759 |
| Yif1a | 5617 |
| Ssr1 | 5265 |
| Cxxc1 | 5185 |
| Syvn1 | 5170 |
| Gosr2 | 4983 |
| Add1 | 4820 |
| Gsk3a | 4755 |
| Serp1 | 4345 |
| Fkbp14 | 3754 |
| Klhdc3 | 3597 |
| Sec31a | 2665 |
| Hdgf | 2610 |
| Extl2 | 1799 |
| Zbtb17 | 1437 |
| Shc1 | 1324 |
| Tln1 | 569 |
| Pla2g4b | 350 |
| Extl3 | 129 |
| Ddx11 | -7 |
| Tspyl2 | -19 |
| Cul7 | -176 |
| Mydgf | -424 |
| Sult1a1 | -440 |
| Ctdsp2 | -499 |
| Arfgap1 | -632 |
| Edem1 | -1060 |
| Ern1 | -1074 |
| Tatdn2 | -2664 |
| Wfs1 | -2874 |
| Extl1 | -3824 |
| Acadvl | -5477 |
| Wipi1 | -6582 |
| Pdia5 | -6749 |
KERATAN SULFATE DEGRADATION
| set | KERATAN SULFATE DEGRADATION |
| setSize | 11 |
| pANOVA | 0.0284 |
| s.dist | 0.382 |
| p.adjustANOVA | 0.114 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Prelp | 8307 |
| Hexa | 5634 |
| Acan | 5263 |
| Gns | 4657 |
| Hexb | 4302 |
| Fmod | 4019 |
| Lum | 3387 |
| Glb1 | 2203 |
| Glb1l | 553 |
| Ogn | -1935 |
| Galns | -4082 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Prelp | 8307 |
| Hexa | 5634 |
| Acan | 5263 |
| Gns | 4657 |
| Hexb | 4302 |
| Fmod | 4019 |
| Lum | 3387 |
| Glb1 | 2203 |
| Glb1l | 553 |
| Ogn | -1935 |
| Galns | -4082 |
ACTIVATION OF AMPK DOWNSTREAM OF NMDARS
| set | ACTIVATION OF AMPK DOWNSTREAM OF NMDARS |
| setSize | 20 |
| pANOVA | 0.00335 |
| s.dist | 0.379 |
| p.adjustANOVA | 0.0262 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Tubb4b | 7623 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Tuba4a | 7209 |
| Tuba1a | 7068 |
| Prkab1 | 6045 |
| Tubb3 | 5844 |
| Prkag2 | 5798 |
| Tuba1c | 4486 |
| Tubb6 | 1808 |
| Prkag1 | 1595 |
| Prkaa1 | 1546 |
| Prkaa2 | 1347 |
| Calm1 | 452 |
| Mapt | -5196 |
| Tuba8 | -5580 |
| Prkab2 | -5820 |
| Camkk2 | -7042 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Tubb4b | 7623 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Tuba4a | 7209 |
| Tuba1a | 7068 |
| Prkab1 | 6045 |
| Tubb3 | 5844 |
| Prkag2 | 5798 |
| Tuba1c | 4486 |
| Tubb6 | 1808 |
| Prkag1 | 1595 |
| Prkaa1 | 1546 |
| Prkaa2 | 1347 |
| Calm1 | 452 |
| Mapt | -5196 |
| Tuba8 | -5580 |
| Prkab2 | -5820 |
| Camkk2 | -7042 |
RECYCLING PATHWAY OF L1
| set | RECYCLING PATHWAY OF L1 |
| setSize | 40 |
| pANOVA | 3.4e-05 |
| s.dist | 0.379 |
| p.adjustANOVA | 0.000817 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Rps6ka6 | 8267 |
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Ap2m1 | 7792 |
| Tubb4b | 7623 |
| Dnm2 | 7615 |
| Ap2b1 | 7523 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Rps6ka4 | 7348 |
| Tuba4a | 7209 |
| Mapk1 | 7098 |
| Tuba1a | 7068 |
| Ap2a2 | 6985 |
| Ezr | 6777 |
| Ap2a1 | 6112 |
| Tubb3 | 5844 |
| Tuba1c | 4486 |
| Cltc | 4484 |
| Clta | 3557 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Rps6ka6 | 8267 |
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Ap2m1 | 7792 |
| Tubb4b | 7623 |
| Dnm2 | 7615 |
| Ap2b1 | 7523 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Rps6ka4 | 7348 |
| Tuba4a | 7209 |
| Mapk1 | 7098 |
| Tuba1a | 7068 |
| Ap2a2 | 6985 |
| Ezr | 6777 |
| Ap2a1 | 6112 |
| Tubb3 | 5844 |
| Tuba1c | 4486 |
| Cltc | 4484 |
| Clta | 3557 |
| L1cam | 3332 |
| Sh3gl2 | 2858 |
| Src | 2554 |
| Dnm3 | 2300 |
| Rps6ka5 | 2129 |
| Actg1 | 1985 |
| Tubb6 | 1808 |
| Numb | 1403 |
| Dnm1 | 815 |
| Msn | 775 |
| Shtn1 | 78 |
| Rps6ka2 | -977 |
| Rps6ka3 | -1314 |
| Rdx | -1896 |
| Ap2s1 | -3478 |
| Rps6ka1 | -4790 |
| Tuba8 | -5580 |
| Dpysl2 | -5753 |
| Actb | -8390 |
| Kif4 | -8456 |
POST CHAPERONIN TUBULIN FOLDING PATHWAY
| set | POST CHAPERONIN TUBULIN FOLDING PATHWAY |
| setSize | 17 |
| pANOVA | 0.00701 |
| s.dist | 0.378 |
| p.adjustANOVA | 0.0449 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Tubb4b | 7623 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Tuba4a | 7209 |
| Tuba1a | 7068 |
| Tbcd | 7047 |
| Tubb3 | 5844 |
| Tuba1c | 4486 |
| Tubb6 | 1808 |
| Arl2 | -1610 |
| Tbcb | -1675 |
| Tbcc | -2974 |
| Tbca | -5116 |
| Tuba8 | -5580 |
| Tbce | -5841 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Tubb2a | 8130 |
| Tuba1b | 7873 |
| Tubb4b | 7623 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Tuba4a | 7209 |
| Tuba1a | 7068 |
| Tbcd | 7047 |
| Tubb3 | 5844 |
| Tuba1c | 4486 |
| Tubb6 | 1808 |
| Arl2 | -1610 |
| Tbcb | -1675 |
| Tbcc | -2974 |
| Tbca | -5116 |
| Tuba8 | -5580 |
| Tbce | -5841 |
COPI MEDIATED ANTEROGRADE TRANSPORT
| set | COPI MEDIATED ANTEROGRADE TRANSPORT |
| setSize | 91 |
| pANOVA | 5.74e-10 |
| s.dist | 0.376 |
| p.adjustANOVA | 5.21e-08 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| Tmed9 | 8187 |
| Tubb2a | 8130 |
| Arf4 | 8012 |
| Tmed2 | 7972 |
| Tuba1b | 7873 |
| Cog4 | 7856 |
| Capza2 | 7704 |
| Tmed7 | 7628 |
| Tubb4b | 7623 |
| Cog1 | 7547 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Copb1 | 7478 |
| Actr1a | 7390 |
| Capza1 | 7254 |
| Tuba4a | 7209 |
| Dctn4 | 7178 |
| Tuba1a | 7068 |
| Cog6 | 6961 |
| Arf1 | 6878 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| Tmed9 | 8187 |
| Tubb2a | 8130 |
| Arf4 | 8012 |
| Tmed2 | 7972 |
| Tuba1b | 7873 |
| Cog4 | 7856 |
| Capza2 | 7704 |
| Tmed7 | 7628 |
| Tubb4b | 7623 |
| Cog1 | 7547 |
| Tubb4a | 7518 |
| Tubb2b | 7505 |
| Copb1 | 7478 |
| Actr1a | 7390 |
| Capza1 | 7254 |
| Tuba4a | 7209 |
| Dctn4 | 7178 |
| Tuba1a | 7068 |
| Cog6 | 6961 |
| Arf1 | 6878 |
| Kdelr1 | 6863 |
| Uso1 | 6854 |
| Dctn6 | 6466 |
| Arcn1 | 6446 |
| Cd55 | 6368 |
| Rab1b | 6317 |
| Dctn1 | 6190 |
| Rab1a | 6147 |
| Kdelr3 | 6078 |
| Tmed10 | 6030 |
| Napg | 5984 |
| Tubb3 | 5844 |
| Dync1i1 | 5761 |
| Arfgap3 | 5743 |
| Napa | 5705 |
| Folr1 | 5699 |
| Dctn5 | 5435 |
| Arfgap2 | 5270 |
| Capzb | 5210 |
| Gosr2 | 4983 |
| Nsf | 4519 |
| Tmed3 | 4494 |
| Tuba1c | 4486 |
| Tmem115 | 4276 |
| Ykt6 | 4252 |
| Copa | 4199 |
| Gorasp1 | 4113 |
| Copb2 | 3646 |
| Dynll1 | 3614 |
| Copz1 | 3592 |
| Gbf1 | 3364 |
| Dctn2 | 3316 |
| Cope | 3295 |
| Cog5 | 3264 |
| Copg1 | 3116 |
| Actr10 | 2964 |
| Dync1li1 | 2626 |
| Napb | 2384 |
| Tubb6 | 1808 |
| Arf3 | 1385 |
| Dync1h1 | 1341 |
| Sptbn5 | 1070 |
| Cog2 | 853 |
| Copg2 | 839 |
| Sptan1 | 631 |
| Stx5a | 590 |
| Dctn3 | 330 |
| Cog7 | 83 |
| Bet1 | -245 |
| Gosr1 | -355 |
| Arfgap1 | -632 |
| Sptbn1 | -846 |
| Arf5 | -1490 |
| Cog8 | -1845 |
| Dynll2 | -1892 |
| Cog3 | -2029 |
| Sptbn2 | -2337 |
| Sptb | -2665 |
| Golga2 | -3178 |
| Sptbn4 | -3400 |
| Copz2 | -3438 |
| Dync1li2 | -3544 |
| Dync1i2 | -3904 |
| Ank1 | -5323 |
| Cd59b | -5416 |
| Tuba8 | -5580 |
| Kdelr2 | -5782 |
| Ank2 | -6068 |
| Bet1l | -7427 |
| Golgb1 | -7437 |
| Ank3 | -8754 |
Here is the session info with all the versions of packages used.
sessionInfo()## R version 4.4.0 (2024-04-24)
## Platform: x86_64-pc-linux-gnu
## Running under: Ubuntu 22.04.4 LTS
##
## Matrix products: default
## BLAS: /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.10.0
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.10.0
##
## locale:
## [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
## [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8
## [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
## [7] LC_PAPER=en_US.UTF-8 LC_NAME=C
## [9] LC_ADDRESS=C LC_TELEPHONE=C
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
##
## time zone: Australia/Melbourne
## tzcode source: system (glibc)
##
## attached base packages:
## [1] stats4 stats graphics grDevices utils datasets methods
## [8] base
##
## other attached packages:
## [1] GGally_2.2.1 ggplot2_3.5.1
## [3] gtools_3.9.5 tibble_3.2.1
## [5] dplyr_1.1.4 echarts4r_0.4.5
## [7] beeswarm_0.4.0 pkgload_1.3.4
## [9] vioplot_0.4.0 sm_2.2-6.0
## [11] kableExtra_1.4.0 topconfects_1.20.0
## [13] limma_3.60.0 eulerr_7.0.2
## [15] mitch_1.16.0 MASS_7.3-60.2
## [17] fgsea_1.30.0 gplots_3.1.3.1
## [19] DESeq2_1.44.0 SummarizedExperiment_1.34.0
## [21] Biobase_2.64.0 MatrixGenerics_1.16.0
## [23] matrixStats_1.3.0 GenomicRanges_1.56.0
## [25] GenomeInfoDb_1.40.0 IRanges_2.38.0
## [27] S4Vectors_0.42.0 BiocGenerics_0.50.0
## [29] reshape2_1.4.4 zoo_1.8-12
##
## loaded via a namespace (and not attached):
## [1] bitops_1.0-7 gridExtra_2.3 rlang_1.1.3
## [4] magrittr_2.0.3 compiler_4.4.0 polylabelr_0.2.0
## [7] systemfonts_1.1.0 vctrs_0.6.5 stringr_1.5.1
## [10] pkgconfig_2.0.3 crayon_1.5.2 fastmap_1.2.0
## [13] XVector_0.44.0 labeling_0.4.3 caTools_1.18.2
## [16] utf8_1.2.4 promises_1.3.0 rmarkdown_2.27
## [19] UCSC.utils_1.0.0 purrr_1.0.2 xfun_0.44
## [22] zlibbioc_1.50.0 cachem_1.1.0 jsonlite_1.8.8
## [25] progress_1.2.3 highr_0.11 later_1.3.2
## [28] DelayedArray_0.30.1 BiocParallel_1.38.0 prettyunits_1.2.0
## [31] parallel_4.4.0 R6_2.5.1 bslib_0.7.0
## [34] stringi_1.8.4 RColorBrewer_1.1-3 jquerylib_0.1.4
## [37] Rcpp_1.0.12 assertthat_0.2.1 knitr_1.47
## [40] httpuv_1.6.15 Matrix_1.7-0 tidyselect_1.2.1
## [43] rstudioapi_0.16.0 abind_1.4-5 yaml_2.3.8
## [46] codetools_0.2-20 lattice_0.22-6 plyr_1.8.9
## [49] withr_3.0.0 shiny_1.8.1.1 evaluate_0.23
## [52] polyclip_1.10-6 ggstats_0.6.0 xml2_1.3.6
## [55] pillar_1.9.0 KernSmooth_2.23-24 generics_0.1.3
## [58] hms_1.1.3 munsell_0.5.1 scales_1.3.0
## [61] xtable_1.8-4 glue_1.7.0 tools_4.4.0
## [64] data.table_1.15.4 locfit_1.5-9.9 fastmatch_1.1-4
## [67] cowplot_1.1.3 grid_4.4.0 tidyr_1.3.1
## [70] colorspace_2.1-0 GenomeInfoDbData_1.2.12 cli_3.6.2
## [73] fansi_1.0.6 S4Arrays_1.4.0 viridisLite_0.4.2
## [76] svglite_2.1.3 gtable_0.3.5 sass_0.4.9
## [79] digest_0.6.35 SparseArray_1.4.3 farver_2.1.2
## [82] htmlwidgets_1.6.4 htmltools_0.5.8.1 lifecycle_1.0.4
## [85] httr_1.4.7 statmod_1.5.0 mime_0.12END of report