Mitch Report
Antony Kaspi & Mark Ziemann
date generated: 2022-10-13
Background
Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch
Input profiles
Here is the first few lines of the input profile.
## hyp hip amy pag ni
## 0610009B22Rik -1.1049767 -0.23239644 0.19606842 0.5780015 -0.23492611
## 0610009E02Rik 0.6328195 -1.02165121 2.50381380 0.4394343 -0.09139988
## 0610009L18Rik -1.8903112 -0.01240851 0.71226654 1.4508124 -1.43010001
## 0610010K14Rik 0.5240337 -0.07303716 -0.06247159 2.1194691 -0.78295210
## 0610012G03Rik -0.2555955 0.88341789 -0.08438765 2.6585547 -0.10566247
## 0610030E20Rik 0.7313254 0.32408607 -0.30737084 -1.5015909 -0.39636314| Profile metrics | |
|---|---|
| num_genes_in_profile | 15984 |
| duplicated_genes_present | 0 |
| num_profile_genes_in_sets | 8078 |
| num_profile_genes_not_in_sets | 7906 |
Here is a plot of the input profiles. Note the dynamic ranges. 
Here is the contour plot of the profile including all detected genes. 
Input genesets
Here are some metrics about the gene sets used: GMT file of genesets: mouse_msigdb_reactome_2022-02-16.gmt| Gene sets metrics | |
|---|---|
| num_genesets | 1604 |
| num_genesets_excluded | 452 |
| num_genesets_included | 1152 |
| hyp | hip | amy | pag | ni | Count | |
|---|---|---|---|---|---|---|
| 1 | -1 | -1 | -1 | -1 | -1 | 1186 |
| 2 | 1 | -1 | -1 | -1 | -1 | 505 |
| 3 | -1 | 1 | -1 | -1 | -1 | 367 |
| 4 | 1 | 1 | -1 | -1 | -1 | 224 |
| 5 | -1 | -1 | 1 | -1 | -1 | 417 |
| 6 | 1 | -1 | 1 | -1 | -1 | 503 |
| 7 | -1 | 1 | 1 | -1 | -1 | 217 |
| 8 | 1 | 1 | 1 | -1 | -1 | 310 |
| 9 | -1 | -1 | -1 | 0 | -1 | 1 |
| 10 | -1 | -1 | -1 | 1 | -1 | 650 |
| 11 | 1 | -1 | -1 | 1 | -1 | 228 |
| 12 | -1 | 1 | -1 | 1 | -1 | 704 |
| 13 | 1 | 1 | -1 | 1 | -1 | 238 |
| 14 | -1 | -1 | 0 | 1 | -1 | 1 |
| 15 | -1 | -1 | 1 | 1 | -1 | 523 |
| 16 | 1 | -1 | 1 | 1 | -1 | 319 |
| 17 | -1 | 0 | 1 | 1 | -1 | 1 |
| 18 | -1 | 1 | 1 | 1 | -1 | 640 |
| 19 | 1 | 1 | 1 | 1 | -1 | 465 |
| 20 | 1 | -1 | -1 | -1 | 0 | 1 |
| 21 | -1 | -1 | -1 | -1 | 1 | 833 |
| 22 | 1 | -1 | -1 | -1 | 1 | 686 |
| 23 | -1 | 1 | -1 | -1 | 1 | 388 |
| 24 | 0 | 1 | -1 | -1 | 1 | 1 |
| 25 | 1 | 1 | -1 | -1 | 1 | 407 |
| 26 | -1 | -1 | 1 | -1 | 1 | 357 |
| 27 | 1 | -1 | 1 | -1 | 1 | 1054 |
| 28 | -1 | 1 | 1 | -1 | 1 | 240 |
| 29 | 1 | 1 | 1 | -1 | 1 | 721 |
| 30 | -1 | -1 | -1 | 1 | 1 | 363 |
| 31 | 1 | -1 | -1 | 1 | 1 | 244 |
| 32 | -1 | 1 | -1 | 1 | 1 | 512 |
| 33 | 1 | 1 | -1 | 1 | 1 | 451 |
| 34 | -1 | -1 | 1 | 1 | 1 | 299 |
| 35 | 1 | -1 | 1 | 1 | 1 | 449 |
| 36 | -1 | 1 | 1 | 1 | 1 | 476 |
| 37 | 1 | 1 | 1 | 1 | 1 | 1003 |
Gene sets by sector
| s.hyp | s.hip | s.amy | s.pag | s.ni | Count | |
|---|---|---|---|---|---|---|
| 1 | -1 | -1 | -1 | -1 | -1 | 33 |
| 2 | 1 | -1 | -1 | -1 | -1 | 3 |
| 3 | -1 | 1 | -1 | -1 | -1 | 1 |
| 4 | 1 | 1 | -1 | -1 | -1 | 5 |
| 5 | -1 | -1 | 1 | -1 | -1 | 8 |
| 6 | 1 | -1 | 1 | -1 | -1 | 5 |
| 7 | -1 | 1 | 1 | -1 | -1 | 2 |
| 8 | 1 | 1 | 1 | -1 | -1 | 1 |
| 9 | -1 | -1 | -1 | 1 | -1 | 36 |
| 10 | -1 | 1 | -1 | 1 | -1 | 58 |
| 11 | 1 | 1 | -1 | 1 | -1 | 1 |
| 12 | -1 | -1 | 1 | 1 | -1 | 28 |
| 13 | 1 | -1 | 1 | 1 | -1 | 2 |
| 14 | -1 | 1 | 1 | 1 | -1 | 56 |
| 15 | -1 | -1 | -1 | -1 | 1 | 18 |
| 16 | 1 | -1 | -1 | -1 | 1 | 17 |
| 17 | -1 | 1 | -1 | -1 | 1 | 3 |
| 18 | 1 | 1 | -1 | -1 | 1 | 5 |
| 19 | -1 | -1 | 1 | -1 | 1 | 13 |
| 20 | 1 | -1 | 1 | -1 | 1 | 81 |
| 21 | -1 | 1 | 1 | -1 | 1 | 1 |
| 22 | 1 | 1 | 1 | -1 | 1 | 16 |
| 23 | -1 | -1 | -1 | 1 | 1 | 7 |
| 24 | 1 | -1 | -1 | 1 | 1 | 1 |
| 25 | -1 | 1 | -1 | 1 | 1 | 7 |
| 26 | 1 | 1 | -1 | 1 | 1 | 9 |
| 27 | -1 | -1 | 1 | 1 | 1 | 12 |
| 28 | -1 | 1 | 1 | 1 | 1 | 11 |
| 29 | 1 | 1 | 1 | 1 | 1 | 16 |
Interactive enrichment scatterplot
All sets with FDR<0.05. Try hovering over the points.
Top N sets irrespective of FDR. Try hovering over the points.
A heatmap of S values for top results
A plot of effect size versus significance
Significance is the -log2(p.adjustMANOVA) and effect size is the s.dist which is the hypotenuse of the s scores.
Results table
Top N= 50 gene sets| set | setSize | pMANOVA | p.adjustMANOVA | s.dist | s.hyp | s.hip | s.amy | s.pag | s.ni | p.hyp | p.hip | p.amy | p.pag | p.ni |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EUKARYOTIC TRANSLATION ELONGATION | 87 | 4.25e-70 | 2.45e-67 | 1.230 | -0.5120 | 0.1370 | -0.20400 | 0.85700 | -0.67800 | 1.54e-16 | 2.73e-02 | 1.02e-03 | 1.20e-43 | 7.01e-28 |
| RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY | 94 | 8.77e-65 | 2.53e-62 | 1.140 | -0.4870 | 0.0738 | -0.21100 | 0.76200 | -0.66000 | 3.28e-16 | 2.17e-01 | 4.01e-04 | 1.89e-37 | 1.80e-28 |
| SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | 106 | 6.08e-69 | 2.33e-66 | 1.100 | -0.4810 | 0.0605 | -0.20600 | 0.75500 | -0.61100 | 1.13e-17 | 2.82e-01 | 2.43e-04 | 2.89e-41 | 1.58e-27 |
| ATTENUATION PHASE | 23 | 8.18e-10 | 1.33e-08 | 1.090 | -0.5550 | -0.4740 | -0.39000 | -0.38200 | -0.59400 | 4.09e-06 | 8.30e-05 | 1.20e-03 | 1.53e-03 | 8.16e-07 |
| ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES | 10 | 4.53e-04 | 2.25e-03 | 1.080 | -0.5160 | -0.6620 | -0.50300 | -0.17100 | -0.41400 | 4.70e-03 | 2.89e-04 | 5.89e-03 | 3.50e-01 | 2.34e-02 |
| EUKARYOTIC TRANSLATION INITIATION | 114 | 4.37e-62 | 8.39e-60 | 1.010 | -0.4260 | 0.1060 | -0.13500 | 0.74400 | -0.50100 | 3.80e-15 | 5.03e-02 | 1.28e-02 | 5.38e-43 | 2.36e-20 |
| SELENOAMINO ACID METABOLISM | 107 | 6.38e-57 | 8.17e-55 | 1.010 | -0.4230 | 0.1280 | -0.15800 | 0.71700 | -0.52500 | 4.10e-14 | 2.27e-02 | 4.68e-03 | 1.01e-37 | 5.83e-21 |
| NONSENSE MEDIATED DECAY NMD | 109 | 1.23e-54 | 1.29e-52 | 0.972 | -0.3850 | 0.0938 | -0.12000 | 0.66900 | -0.57200 | 3.96e-12 | 9.08e-02 | 3.07e-02 | 1.36e-33 | 5.59e-25 |
| COMPLEX I BIOGENESIS | 56 | 3.98e-28 | 2.29e-26 | 0.971 | -0.5040 | 0.0518 | -0.06440 | 0.72200 | -0.40200 | 6.85e-11 | 5.02e-01 | 4.05e-01 | 8.79e-21 | 1.90e-07 |
| HSF1 ACTIVATION | 25 | 1.20e-07 | 1.38e-06 | 0.942 | -0.5870 | -0.3990 | -0.41800 | -0.18600 | -0.41700 | 3.83e-07 | 5.47e-04 | 2.93e-04 | 1.07e-01 | 3.06e-04 |
| ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | 59 | 6.17e-25 | 3.23e-23 | 0.908 | -0.4480 | 0.0815 | -0.11300 | 0.65900 | -0.41200 | 2.57e-09 | 2.79e-01 | 1.34e-01 | 2.03e-18 | 4.51e-08 |
| MITOCHONDRIAL TRANSLATION | 93 | 8.92e-39 | 5.71e-37 | 0.893 | -0.3170 | 0.2560 | -0.03590 | 0.74800 | -0.26700 | 1.24e-07 | 2.01e-05 | 5.50e-01 | 9.42e-36 | 8.92e-06 |
| RESPIRATORY ELECTRON TRANSPORT | 102 | 1.10e-43 | 9.74e-42 | 0.882 | -0.4400 | 0.0842 | -0.05910 | 0.69700 | -0.29800 | 1.70e-14 | 1.42e-01 | 3.02e-01 | 3.70e-34 | 2.11e-07 |
| ADENYLATE CYCLASE ACTIVATING PATHWAY | 10 | 1.18e-03 | 4.97e-03 | 0.875 | 0.3020 | -0.2610 | 0.17700 | -0.73600 | 0.18000 | 9.83e-02 | 1.53e-01 | 3.32e-01 | 5.54e-05 | 3.23e-01 |
| MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS | 13 | 2.23e-04 | 1.18e-03 | 0.867 | -0.3980 | 0.2210 | -0.16100 | 0.63100 | -0.34900 | 1.29e-02 | 1.69e-01 | 3.14e-01 | 8.26e-05 | 2.95e-02 |
| REGULATION OF EXPRESSION OF SLITS AND ROBOS | 159 | 1.64e-62 | 3.77e-60 | 0.866 | -0.4130 | 0.0693 | -0.07520 | 0.59300 | -0.46600 | 2.84e-19 | 1.32e-01 | 1.02e-01 | 3.09e-38 | 3.43e-24 |
| FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | 18 | 1.68e-07 | 1.89e-06 | 0.857 | -0.3070 | -0.0183 | -0.12900 | 0.74400 | -0.26500 | 2.42e-02 | 8.93e-01 | 3.45e-01 | 4.54e-08 | 5.15e-02 |
| RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | 125 | 1.57e-49 | 1.51e-47 | 0.841 | -0.3890 | 0.0804 | -0.06970 | 0.68700 | -0.27000 | 5.65e-14 | 1.21e-01 | 1.79e-01 | 3.01e-40 | 1.81e-07 |
| SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | 11 | 1.16e-03 | 4.95e-03 | 0.826 | -0.4420 | 0.1650 | 0.19900 | 0.53700 | -0.36400 | 1.12e-02 | 3.42e-01 | 2.54e-01 | 2.05e-03 | 3.68e-02 |
| REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO | 10 | 1.07e-03 | 4.64e-03 | 0.818 | 0.2330 | -0.1030 | 0.56700 | -0.49000 | 0.20800 | 2.02e-01 | 5.72e-01 | 1.91e-03 | 7.29e-03 | 2.56e-01 |
| FORMATION OF FIBRIN CLOT CLOTTING CASCADE | 18 | 8.81e-07 | 8.38e-06 | 0.811 | 0.1690 | 0.6310 | -0.29300 | 0.29700 | 0.23900 | 2.14e-01 | 3.56e-06 | 3.12e-02 | 2.91e-02 | 7.93e-02 |
| SIGNALING BY HIPPO | 20 | 7.87e-07 | 7.75e-06 | 0.806 | -0.4010 | -0.0681 | -0.41800 | -0.54300 | 0.12000 | 1.90e-03 | 5.98e-01 | 1.20e-03 | 2.62e-05 | 3.51e-01 |
| RHOBTB2 GTPASE CYCLE | 23 | 3.79e-05 | 2.44e-04 | 0.796 | -0.4220 | -0.3850 | -0.23600 | -0.23800 | -0.44200 | 4.66e-04 | 1.39e-03 | 4.98e-02 | 4.84e-02 | 2.45e-04 |
| CAMK IV MEDIATED PHOSPHORYLATION OF CREB | 10 | 8.28e-03 | 2.51e-02 | 0.781 | 0.3490 | -0.2550 | 0.49600 | -0.14000 | 0.39800 | 5.63e-02 | 1.63e-01 | 6.62e-03 | 4.44e-01 | 2.95e-02 |
| CRISTAE FORMATION | 31 | 1.60e-10 | 2.79e-09 | 0.781 | -0.2750 | 0.0520 | -0.07630 | 0.69000 | -0.22200 | 8.11e-03 | 6.17e-01 | 4.62e-01 | 2.84e-11 | 3.23e-02 |
| TRANSLATION | 286 | 8.05e-94 | 9.27e-91 | 0.780 | -0.3350 | 0.1410 | -0.07790 | 0.61800 | -0.29800 | 1.99e-22 | 4.36e-05 | 2.38e-02 | 1.27e-72 | 4.67e-18 |
| REGULATION OF RUNX1 EXPRESSION AND ACTIVITY | 17 | 1.83e-04 | 9.97e-04 | 0.779 | 0.1190 | -0.4290 | -0.16300 | -0.57800 | -0.22100 | 3.96e-01 | 2.22e-03 | 2.44e-01 | 3.72e-05 | 1.15e-01 |
| ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K | 11 | 5.54e-03 | 1.81e-02 | 0.777 | 0.1510 | -0.6350 | -0.08550 | -0.40200 | 0.09190 | 3.85e-01 | 2.64e-04 | 6.24e-01 | 2.09e-02 | 5.98e-01 |
| INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION | 12 | 1.69e-04 | 9.28e-04 | 0.775 | 0.0314 | 0.5990 | -0.42900 | 0.16500 | 0.16900 | 8.51e-01 | 3.25e-04 | 1.00e-02 | 3.22e-01 | 3.12e-01 |
| UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION | 21 | 1.63e-05 | 1.14e-04 | 0.769 | 0.4370 | -0.2780 | 0.40600 | -0.29300 | 0.26900 | 5.23e-04 | 2.77e-02 | 1.28e-03 | 2.03e-02 | 3.29e-02 |
| REDUCTION OF CYTOSOLIC CA LEVELS | 11 | 1.31e-02 | 3.62e-02 | 0.763 | 0.4460 | -0.1730 | 0.27200 | -0.31900 | 0.42200 | 1.05e-02 | 3.19e-01 | 1.19e-01 | 6.74e-02 | 1.53e-02 |
| TRAF6 MEDIATED IRF7 ACTIVATION | 15 | 3.31e-03 | 1.18e-02 | 0.756 | -0.1760 | -0.4480 | -0.38500 | -0.43500 | 0.04760 | 2.38e-01 | 2.64e-03 | 9.89e-03 | 3.54e-03 | 7.50e-01 |
| TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | 17 | 4.81e-04 | 2.38e-03 | 0.747 | 0.4410 | -0.1000 | 0.55400 | -0.11200 | 0.18500 | 1.66e-03 | 4.75e-01 | 7.59e-05 | 4.22e-01 | 1.86e-01 |
| LONG TERM POTENTIATION | 23 | 1.26e-05 | 8.91e-05 | 0.743 | 0.4420 | -0.2890 | 0.32500 | -0.32800 | 0.24600 | 2.44e-04 | 1.65e-02 | 7.00e-03 | 6.50e-03 | 4.10e-02 |
| INFLUENZA INFECTION | 145 | 1.16e-41 | 8.32e-40 | 0.742 | -0.3580 | -0.0182 | -0.10800 | 0.48100 | -0.42300 | 9.47e-14 | 7.05e-01 | 2.55e-02 | 1.38e-23 | 1.44e-18 |
| SYNAPTIC ADHESION LIKE MOLECULES | 21 | 7.75e-06 | 5.95e-05 | 0.742 | 0.3280 | -0.1230 | 0.52000 | -0.37100 | 0.14300 | 9.20e-03 | 3.30e-01 | 3.74e-05 | 3.26e-03 | 2.55e-01 |
| CELLULAR RESPONSE TO STARVATION | 145 | 3.07e-43 | 2.35e-41 | 0.741 | -0.3040 | 0.0548 | -0.06220 | 0.57100 | -0.35100 | 2.59e-10 | 2.56e-01 | 1.97e-01 | 1.47e-32 | 3.19e-13 |
| PKA MEDIATED PHOSPHORYLATION OF CREB | 19 | 5.46e-05 | 3.33e-04 | 0.740 | -0.0309 | -0.3860 | 0.05160 | -0.61200 | 0.14500 | 8.16e-01 | 3.58e-03 | 6.97e-01 | 3.84e-06 | 2.74e-01 |
| RRNA PROCESSING | 194 | 2.68e-56 | 3.08e-54 | 0.731 | -0.2900 | 0.0620 | -0.00171 | 0.54400 | -0.38800 | 3.49e-12 | 1.37e-01 | 9.67e-01 | 4.44e-39 | 1.21e-20 |
| BIOTIN TRANSPORT AND METABOLISM | 11 | 7.31e-03 | 2.26e-02 | 0.730 | 0.1110 | 0.5500 | 0.33800 | -0.00956 | 0.32300 | 5.24e-01 | 1.57e-03 | 5.25e-02 | 9.56e-01 | 6.40e-02 |
| CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE | 11 | 1.13e-02 | 3.21e-02 | 0.724 | -0.3190 | -0.4050 | -0.15100 | -0.46600 | 0.13600 | 6.72e-02 | 2.02e-02 | 3.87e-01 | 7.40e-03 | 4.34e-01 |
| NEGATIVE REGULATION OF NOTCH4 SIGNALING | 54 | 4.60e-16 | 1.89e-14 | 0.724 | -0.3820 | 0.0500 | 0.08490 | 0.58200 | -0.17000 | 1.18e-06 | 5.25e-01 | 2.81e-01 | 1.31e-13 | 3.05e-02 |
| PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING | 11 | 9.16e-03 | 2.75e-02 | 0.721 | 0.3950 | -0.2320 | 0.40200 | -0.38600 | 0.02240 | 2.34e-02 | 1.83e-01 | 2.11e-02 | 2.67e-02 | 8.98e-01 |
| COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING | 26 | 1.69e-06 | 1.53e-05 | 0.719 | -0.4880 | -0.1340 | -0.05830 | 0.37000 | -0.34800 | 1.65e-05 | 2.37e-01 | 6.07e-01 | 1.10e-03 | 2.11e-03 |
| TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | 13 | 1.96e-02 | 4.96e-02 | 0.716 | -0.2110 | -0.4010 | -0.34700 | -0.43300 | 0.00433 | 1.89e-01 | 1.23e-02 | 3.04e-02 | 6.84e-03 | 9.78e-01 |
| ADENYLATE CYCLASE INHIBITORY PATHWAY | 13 | 2.99e-03 | 1.09e-02 | 0.714 | 0.0959 | -0.2210 | 0.02000 | -0.66200 | 0.11300 | 5.49e-01 | 1.67e-01 | 9.01e-01 | 3.53e-05 | 4.80e-01 |
| MITOCHONDRIAL PROTEIN IMPORT | 63 | 2.86e-17 | 1.27e-15 | 0.712 | -0.2390 | 0.1760 | 0.04490 | 0.64300 | -0.06040 | 1.03e-03 | 1.60e-02 | 5.38e-01 | 9.77e-19 | 4.07e-01 |
| MUCOPOLYSACCHARIDOSES | 11 | 6.18e-03 | 1.95e-02 | 0.711 | 0.2360 | 0.4280 | 0.43800 | -0.19200 | 0.19200 | 1.75e-01 | 1.39e-02 | 1.19e-02 | 2.69e-01 | 2.70e-01 |
| NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION | 21 | 6.46e-05 | 3.87e-04 | 0.707 | 0.3520 | -0.3500 | 0.34300 | -0.24300 | 0.27700 | 5.26e-03 | 5.56e-03 | 6.54e-03 | 5.37e-02 | 2.81e-02 |
| ATF6 ATF6 ALPHA ACTIVATES CHAPERONES | 12 | 4.70e-02 | 9.94e-02 | 0.704 | -0.3330 | -0.4040 | -0.38800 | -0.13700 | -0.22700 | 4.58e-02 | 1.54e-02 | 1.99e-02 | 4.11e-01 | 1.73e-01 |
Results (complete table)
Click HERE to show results for all gene sets
| set | setSize | pMANOVA | p.adjustMANOVA | s.dist | s.hyp | s.hip | s.amy | s.pag | s.ni | p.hyp | p.hip | p.amy | p.pag | p.ni |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EUKARYOTIC TRANSLATION ELONGATION | 87 | 4.25e-70 | 2.45e-67 | 1.2300 | -0.512000 | 0.137000 | -0.204000 | 8.57e-01 | -6.78e-01 | 1.54e-16 | 2.73e-02 | 1.02e-03 | 1.20e-43 | 7.01e-28 |
| RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY | 94 | 8.77e-65 | 2.53e-62 | 1.1400 | -0.487000 | 0.073800 | -0.211000 | 7.62e-01 | -6.60e-01 | 3.28e-16 | 2.17e-01 | 4.01e-04 | 1.89e-37 | 1.80e-28 |
| SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | 106 | 6.08e-69 | 2.33e-66 | 1.1000 | -0.481000 | 0.060500 | -0.206000 | 7.55e-01 | -6.11e-01 | 1.13e-17 | 2.82e-01 | 2.43e-04 | 2.89e-41 | 1.58e-27 |
| ATTENUATION PHASE | 23 | 8.18e-10 | 1.33e-08 | 1.0900 | -0.555000 | -0.474000 | -0.390000 | -3.82e-01 | -5.94e-01 | 4.09e-06 | 8.30e-05 | 1.20e-03 | 1.53e-03 | 8.16e-07 |
| ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES | 10 | 4.53e-04 | 2.25e-03 | 1.0800 | -0.516000 | -0.662000 | -0.503000 | -1.71e-01 | -4.14e-01 | 4.70e-03 | 2.89e-04 | 5.89e-03 | 3.50e-01 | 2.34e-02 |
| EUKARYOTIC TRANSLATION INITIATION | 114 | 4.37e-62 | 8.39e-60 | 1.0100 | -0.426000 | 0.106000 | -0.135000 | 7.44e-01 | -5.01e-01 | 3.80e-15 | 5.03e-02 | 1.28e-02 | 5.38e-43 | 2.36e-20 |
| SELENOAMINO ACID METABOLISM | 107 | 6.38e-57 | 8.17e-55 | 1.0100 | -0.423000 | 0.128000 | -0.158000 | 7.17e-01 | -5.25e-01 | 4.10e-14 | 2.27e-02 | 4.68e-03 | 1.01e-37 | 5.83e-21 |
| NONSENSE MEDIATED DECAY NMD | 109 | 1.23e-54 | 1.29e-52 | 0.9720 | -0.385000 | 0.093800 | -0.120000 | 6.69e-01 | -5.72e-01 | 3.96e-12 | 9.08e-02 | 3.07e-02 | 1.36e-33 | 5.59e-25 |
| COMPLEX I BIOGENESIS | 56 | 3.98e-28 | 2.29e-26 | 0.9710 | -0.504000 | 0.051800 | -0.064400 | 7.22e-01 | -4.02e-01 | 6.85e-11 | 5.02e-01 | 4.05e-01 | 8.79e-21 | 1.90e-07 |
| HSF1 ACTIVATION | 25 | 1.20e-07 | 1.38e-06 | 0.9420 | -0.587000 | -0.399000 | -0.418000 | -1.86e-01 | -4.17e-01 | 3.83e-07 | 5.47e-04 | 2.93e-04 | 1.07e-01 | 3.06e-04 |
| ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | 59 | 6.17e-25 | 3.23e-23 | 0.9080 | -0.448000 | 0.081500 | -0.113000 | 6.59e-01 | -4.12e-01 | 2.57e-09 | 2.79e-01 | 1.34e-01 | 2.03e-18 | 4.51e-08 |
| MITOCHONDRIAL TRANSLATION | 93 | 8.92e-39 | 5.71e-37 | 0.8930 | -0.317000 | 0.256000 | -0.035900 | 7.48e-01 | -2.67e-01 | 1.24e-07 | 2.01e-05 | 5.50e-01 | 9.42e-36 | 8.92e-06 |
| RESPIRATORY ELECTRON TRANSPORT | 102 | 1.10e-43 | 9.74e-42 | 0.8820 | -0.440000 | 0.084200 | -0.059100 | 6.97e-01 | -2.98e-01 | 1.70e-14 | 1.42e-01 | 3.02e-01 | 3.70e-34 | 2.11e-07 |
| ADENYLATE CYCLASE ACTIVATING PATHWAY | 10 | 1.18e-03 | 4.97e-03 | 0.8750 | 0.302000 | -0.261000 | 0.177000 | -7.36e-01 | 1.80e-01 | 9.83e-02 | 1.53e-01 | 3.32e-01 | 5.54e-05 | 3.23e-01 |
| MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS | 13 | 2.23e-04 | 1.18e-03 | 0.8670 | -0.398000 | 0.221000 | -0.161000 | 6.31e-01 | -3.49e-01 | 1.29e-02 | 1.69e-01 | 3.14e-01 | 8.26e-05 | 2.95e-02 |
| REGULATION OF EXPRESSION OF SLITS AND ROBOS | 159 | 1.64e-62 | 3.77e-60 | 0.8660 | -0.413000 | 0.069300 | -0.075200 | 5.93e-01 | -4.66e-01 | 2.84e-19 | 1.32e-01 | 1.02e-01 | 3.09e-38 | 3.43e-24 |
| FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | 18 | 1.68e-07 | 1.89e-06 | 0.8570 | -0.307000 | -0.018300 | -0.129000 | 7.44e-01 | -2.65e-01 | 2.42e-02 | 8.93e-01 | 3.45e-01 | 4.54e-08 | 5.15e-02 |
| RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | 125 | 1.57e-49 | 1.51e-47 | 0.8410 | -0.389000 | 0.080400 | -0.069700 | 6.87e-01 | -2.70e-01 | 5.65e-14 | 1.21e-01 | 1.79e-01 | 3.01e-40 | 1.81e-07 |
| SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | 11 | 1.16e-03 | 4.95e-03 | 0.8260 | -0.442000 | 0.165000 | 0.199000 | 5.37e-01 | -3.64e-01 | 1.12e-02 | 3.42e-01 | 2.54e-01 | 2.05e-03 | 3.68e-02 |
| REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO | 10 | 1.07e-03 | 4.64e-03 | 0.8180 | 0.233000 | -0.103000 | 0.567000 | -4.90e-01 | 2.08e-01 | 2.02e-01 | 5.72e-01 | 1.91e-03 | 7.29e-03 | 2.56e-01 |
| FORMATION OF FIBRIN CLOT CLOTTING CASCADE | 18 | 8.81e-07 | 8.38e-06 | 0.8110 | 0.169000 | 0.631000 | -0.293000 | 2.97e-01 | 2.39e-01 | 2.14e-01 | 3.56e-06 | 3.12e-02 | 2.91e-02 | 7.93e-02 |
| SIGNALING BY HIPPO | 20 | 7.87e-07 | 7.75e-06 | 0.8060 | -0.401000 | -0.068100 | -0.418000 | -5.43e-01 | 1.20e-01 | 1.90e-03 | 5.98e-01 | 1.20e-03 | 2.62e-05 | 3.51e-01 |
| RHOBTB2 GTPASE CYCLE | 23 | 3.79e-05 | 2.44e-04 | 0.7960 | -0.422000 | -0.385000 | -0.236000 | -2.38e-01 | -4.42e-01 | 4.66e-04 | 1.39e-03 | 4.98e-02 | 4.84e-02 | 2.45e-04 |
| CAMK IV MEDIATED PHOSPHORYLATION OF CREB | 10 | 8.28e-03 | 2.51e-02 | 0.7810 | 0.349000 | -0.255000 | 0.496000 | -1.40e-01 | 3.98e-01 | 5.63e-02 | 1.63e-01 | 6.62e-03 | 4.44e-01 | 2.95e-02 |
| CRISTAE FORMATION | 31 | 1.60e-10 | 2.79e-09 | 0.7810 | -0.275000 | 0.052000 | -0.076300 | 6.90e-01 | -2.22e-01 | 8.11e-03 | 6.17e-01 | 4.62e-01 | 2.84e-11 | 3.23e-02 |
| TRANSLATION | 286 | 8.05e-94 | 9.27e-91 | 0.7800 | -0.335000 | 0.141000 | -0.077900 | 6.18e-01 | -2.98e-01 | 1.99e-22 | 4.36e-05 | 2.38e-02 | 1.27e-72 | 4.67e-18 |
| REGULATION OF RUNX1 EXPRESSION AND ACTIVITY | 17 | 1.83e-04 | 9.97e-04 | 0.7790 | 0.119000 | -0.429000 | -0.163000 | -5.78e-01 | -2.21e-01 | 3.96e-01 | 2.22e-03 | 2.44e-01 | 3.72e-05 | 1.15e-01 |
| ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K | 11 | 5.54e-03 | 1.81e-02 | 0.7770 | 0.151000 | -0.635000 | -0.085500 | -4.02e-01 | 9.19e-02 | 3.85e-01 | 2.64e-04 | 6.24e-01 | 2.09e-02 | 5.98e-01 |
| INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION | 12 | 1.69e-04 | 9.28e-04 | 0.7750 | 0.031400 | 0.599000 | -0.429000 | 1.65e-01 | 1.69e-01 | 8.51e-01 | 3.25e-04 | 1.00e-02 | 3.22e-01 | 3.12e-01 |
| UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION | 21 | 1.63e-05 | 1.14e-04 | 0.7690 | 0.437000 | -0.278000 | 0.406000 | -2.93e-01 | 2.69e-01 | 5.23e-04 | 2.77e-02 | 1.28e-03 | 2.03e-02 | 3.29e-02 |
| REDUCTION OF CYTOSOLIC CA LEVELS | 11 | 1.31e-02 | 3.62e-02 | 0.7630 | 0.446000 | -0.173000 | 0.272000 | -3.19e-01 | 4.22e-01 | 1.05e-02 | 3.19e-01 | 1.19e-01 | 6.74e-02 | 1.53e-02 |
| TRAF6 MEDIATED IRF7 ACTIVATION | 15 | 3.31e-03 | 1.18e-02 | 0.7560 | -0.176000 | -0.448000 | -0.385000 | -4.35e-01 | 4.76e-02 | 2.38e-01 | 2.64e-03 | 9.89e-03 | 3.54e-03 | 7.50e-01 |
| TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | 17 | 4.81e-04 | 2.38e-03 | 0.7470 | 0.441000 | -0.100000 | 0.554000 | -1.12e-01 | 1.85e-01 | 1.66e-03 | 4.75e-01 | 7.59e-05 | 4.22e-01 | 1.86e-01 |
| LONG TERM POTENTIATION | 23 | 1.26e-05 | 8.91e-05 | 0.7430 | 0.442000 | -0.289000 | 0.325000 | -3.28e-01 | 2.46e-01 | 2.44e-04 | 1.65e-02 | 7.00e-03 | 6.50e-03 | 4.10e-02 |
| INFLUENZA INFECTION | 145 | 1.16e-41 | 8.32e-40 | 0.7420 | -0.358000 | -0.018200 | -0.108000 | 4.81e-01 | -4.23e-01 | 9.47e-14 | 7.05e-01 | 2.55e-02 | 1.38e-23 | 1.44e-18 |
| SYNAPTIC ADHESION LIKE MOLECULES | 21 | 7.75e-06 | 5.95e-05 | 0.7420 | 0.328000 | -0.123000 | 0.520000 | -3.71e-01 | 1.43e-01 | 9.20e-03 | 3.30e-01 | 3.74e-05 | 3.26e-03 | 2.55e-01 |
| CELLULAR RESPONSE TO STARVATION | 145 | 3.07e-43 | 2.35e-41 | 0.7410 | -0.304000 | 0.054800 | -0.062200 | 5.71e-01 | -3.51e-01 | 2.59e-10 | 2.56e-01 | 1.97e-01 | 1.47e-32 | 3.19e-13 |
| PKA MEDIATED PHOSPHORYLATION OF CREB | 19 | 5.46e-05 | 3.33e-04 | 0.7400 | -0.030900 | -0.386000 | 0.051600 | -6.12e-01 | 1.45e-01 | 8.16e-01 | 3.58e-03 | 6.97e-01 | 3.84e-06 | 2.74e-01 |
| RRNA PROCESSING | 194 | 2.68e-56 | 3.08e-54 | 0.7310 | -0.290000 | 0.062000 | -0.001710 | 5.44e-01 | -3.88e-01 | 3.49e-12 | 1.37e-01 | 9.67e-01 | 4.44e-39 | 1.21e-20 |
| BIOTIN TRANSPORT AND METABOLISM | 11 | 7.31e-03 | 2.26e-02 | 0.7300 | 0.111000 | 0.550000 | 0.338000 | -9.56e-03 | 3.23e-01 | 5.24e-01 | 1.57e-03 | 5.25e-02 | 9.56e-01 | 6.40e-02 |
| CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE | 11 | 1.13e-02 | 3.21e-02 | 0.7240 | -0.319000 | -0.405000 | -0.151000 | -4.66e-01 | 1.36e-01 | 6.72e-02 | 2.02e-02 | 3.87e-01 | 7.40e-03 | 4.34e-01 |
| NEGATIVE REGULATION OF NOTCH4 SIGNALING | 54 | 4.60e-16 | 1.89e-14 | 0.7240 | -0.382000 | 0.050000 | 0.084900 | 5.82e-01 | -1.70e-01 | 1.18e-06 | 5.25e-01 | 2.81e-01 | 1.31e-13 | 3.05e-02 |
| PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING | 11 | 9.16e-03 | 2.75e-02 | 0.7210 | 0.395000 | -0.232000 | 0.402000 | -3.86e-01 | 2.24e-02 | 2.34e-02 | 1.83e-01 | 2.11e-02 | 2.67e-02 | 8.98e-01 |
| COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING | 26 | 1.69e-06 | 1.53e-05 | 0.7190 | -0.488000 | -0.134000 | -0.058300 | 3.70e-01 | -3.48e-01 | 1.65e-05 | 2.37e-01 | 6.07e-01 | 1.10e-03 | 2.11e-03 |
| TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | 13 | 1.96e-02 | 4.96e-02 | 0.7160 | -0.211000 | -0.401000 | -0.347000 | -4.33e-01 | 4.33e-03 | 1.89e-01 | 1.23e-02 | 3.04e-02 | 6.84e-03 | 9.78e-01 |
| ADENYLATE CYCLASE INHIBITORY PATHWAY | 13 | 2.99e-03 | 1.09e-02 | 0.7140 | 0.095900 | -0.221000 | 0.020000 | -6.62e-01 | 1.13e-01 | 5.49e-01 | 1.67e-01 | 9.01e-01 | 3.53e-05 | 4.80e-01 |
| MITOCHONDRIAL PROTEIN IMPORT | 63 | 2.86e-17 | 1.27e-15 | 0.7120 | -0.239000 | 0.176000 | 0.044900 | 6.43e-01 | -6.04e-02 | 1.03e-03 | 1.60e-02 | 5.38e-01 | 9.77e-19 | 4.07e-01 |
| MUCOPOLYSACCHARIDOSES | 11 | 6.18e-03 | 1.95e-02 | 0.7110 | 0.236000 | 0.428000 | 0.438000 | -1.92e-01 | 1.92e-01 | 1.75e-01 | 1.39e-02 | 1.19e-02 | 2.69e-01 | 2.70e-01 |
| NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION | 21 | 6.46e-05 | 3.87e-04 | 0.7070 | 0.352000 | -0.350000 | 0.343000 | -2.43e-01 | 2.77e-01 | 5.26e-03 | 5.56e-03 | 6.54e-03 | 5.37e-02 | 2.81e-02 |
| ATF6 ATF6 ALPHA ACTIVATES CHAPERONES | 12 | 4.70e-02 | 9.94e-02 | 0.7040 | -0.333000 | -0.404000 | -0.388000 | -1.37e-01 | -2.27e-01 | 4.58e-02 | 1.54e-02 | 1.99e-02 | 4.11e-01 | 1.73e-01 |
| PURINE CATABOLISM | 16 | 4.23e-03 | 1.43e-02 | 0.7030 | -0.042100 | 0.455000 | 0.167000 | 4.89e-01 | 1.36e-01 | 7.71e-01 | 1.64e-03 | 2.47e-01 | 7.02e-04 | 3.46e-01 |
| CGMP EFFECTS | 15 | 4.25e-03 | 1.43e-02 | 0.7020 | 0.466000 | -0.089800 | 0.494000 | -5.66e-02 | 1.39e-01 | 1.77e-03 | 5.47e-01 | 9.16e-04 | 7.04e-01 | 3.50e-01 |
| RNA POLYMERASE III CHAIN ELONGATION | 18 | 7.51e-04 | 3.46e-03 | 0.7010 | 0.024600 | 0.279000 | 0.178000 | 6.02e-01 | 1.38e-01 | 8.56e-01 | 4.02e-02 | 1.90e-01 | 9.79e-06 | 3.12e-01 |
| NEUROTOXICITY OF CLOSTRIDIUM TOXINS | 10 | 3.48e-02 | 7.79e-02 | 0.6970 | 0.505000 | -0.186000 | 0.392000 | 8.36e-03 | 2.09e-01 | 5.73e-03 | 3.09e-01 | 3.20e-02 | 9.63e-01 | 2.52e-01 |
| TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS | 15 | 4.01e-03 | 1.38e-02 | 0.6970 | -0.020000 | -0.249000 | -0.267000 | -5.83e-01 | -1.10e-01 | 8.93e-01 | 9.56e-02 | 7.30e-02 | 9.24e-05 | 4.61e-01 |
| ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT | 23 | 1.93e-05 | 1.30e-04 | 0.6910 | -0.155000 | 0.158000 | 0.310000 | 5.08e-01 | -2.73e-01 | 1.99e-01 | 1.91e-01 | 1.00e-02 | 2.45e-05 | 2.36e-02 |
| INCRETIN SYNTHESIS SECRETION AND INACTIVATION | 12 | 2.12e-02 | 5.24e-02 | 0.6900 | -0.559000 | -0.013400 | -0.146000 | 1.88e-01 | -3.28e-01 | 8.06e-04 | 9.36e-01 | 3.82e-01 | 2.58e-01 | 4.94e-02 |
| SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 | 12 | 2.12e-02 | 5.24e-02 | 0.6900 | -0.559000 | -0.013400 | -0.146000 | 1.88e-01 | -3.28e-01 | 8.06e-04 | 9.36e-01 | 3.82e-01 | 2.58e-01 | 4.94e-02 |
| LYSOSPHINGOLIPID AND LPA RECEPTORS | 12 | 3.36e-03 | 1.20e-02 | 0.6890 | -0.118000 | -0.063800 | -0.072300 | -3.35e-01 | -5.83e-01 | 4.81e-01 | 7.02e-01 | 6.65e-01 | 4.45e-02 | 4.76e-04 |
| DNA METHYLATION | 17 | 9.36e-04 | 4.13e-03 | 0.6890 | -0.300000 | 0.147000 | -0.437000 | 3.37e-01 | -2.41e-01 | 3.25e-02 | 2.95e-01 | 1.80e-03 | 1.60e-02 | 8.59e-02 |
| CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | 46 | 8.60e-12 | 2.02e-10 | 0.6850 | -0.366000 | 0.026200 | -0.014400 | 5.50e-01 | -1.79e-01 | 1.73e-05 | 7.59e-01 | 8.66e-01 | 1.12e-10 | 3.56e-02 |
| AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA | 53 | 3.30e-13 | 1.00e-11 | 0.6830 | -0.424000 | -0.016600 | -0.002230 | 4.73e-01 | -2.52e-01 | 9.27e-08 | 8.34e-01 | 9.78e-01 | 2.66e-09 | 1.49e-03 |
| INTERACTION BETWEEN L1 AND ANKYRINS | 27 | 3.92e-06 | 3.16e-05 | 0.6830 | 0.293000 | -0.243000 | 0.365000 | -4.10e-01 | 1.44e-01 | 8.46e-03 | 2.89e-02 | 1.04e-03 | 2.27e-04 | 1.97e-01 |
| CA DEPENDENT EVENTS | 36 | 4.37e-08 | 5.24e-07 | 0.6830 | 0.236000 | -0.268000 | 0.264000 | -4.41e-01 | 2.72e-01 | 1.44e-02 | 5.33e-03 | 6.18e-03 | 4.58e-06 | 4.77e-03 |
| ABC TRANSPORTERS IN LIPID HOMEOSTASIS | 13 | 6.72e-03 | 2.10e-02 | 0.6820 | 0.207000 | -0.006690 | 0.046400 | -3.12e-01 | 5.68e-01 | 1.96e-01 | 9.67e-01 | 7.72e-01 | 5.12e-02 | 3.87e-04 |
| ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 1.42e-03 | 5.75e-03 | 0.6810 | 0.486000 | -0.232000 | 0.360000 | -1.66e-01 | 1.30e-01 | 5.23e-04 | 9.82e-02 | 1.01e-02 | 2.36e-01 | 3.53e-01 |
| SCF SKP2 MEDIATED DEGRADATION OF P27 P21 | 58 | 2.07e-14 | 7.21e-13 | 0.6760 | -0.410000 | 0.076600 | 0.030300 | 5.07e-01 | -1.58e-01 | 6.64e-08 | 3.13e-01 | 6.90e-01 | 2.47e-11 | 3.79e-02 |
| SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | 11 | 1.76e-02 | 4.51e-02 | 0.6690 | 0.151000 | 0.009130 | 0.059000 | -3.55e-01 | 5.43e-01 | 3.87e-01 | 9.58e-01 | 7.35e-01 | 4.13e-02 | 1.83e-03 |
| DAG AND IP3 SIGNALING | 40 | 3.33e-08 | 4.08e-07 | 0.6680 | 0.292000 | -0.264000 | 0.243000 | -3.75e-01 | 3.02e-01 | 1.38e-03 | 3.88e-03 | 7.92e-03 | 4.03e-05 | 9.46e-04 |
| THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT | 172 | 1.29e-43 | 1.06e-41 | 0.6680 | -0.265000 | 0.112000 | -0.050000 | 5.86e-01 | -1.29e-01 | 2.01e-09 | 1.11e-02 | 2.59e-01 | 2.95e-40 | 3.54e-03 |
| COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING | 34 | 2.84e-07 | 3.03e-06 | 0.6590 | -0.423000 | -0.334000 | -0.055400 | 1.83e-01 | -3.27e-01 | 1.94e-05 | 7.65e-04 | 5.76e-01 | 6.54e-02 | 9.76e-04 |
| STABILIZATION OF P53 | 54 | 4.93e-13 | 1.38e-11 | 0.6580 | -0.361000 | -0.030400 | -0.030900 | 5.11e-01 | -1.99e-01 | 4.47e-06 | 6.99e-01 | 6.94e-01 | 8.54e-11 | 1.15e-02 |
| THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT | 65 | 1.17e-15 | 4.49e-14 | 0.6570 | -0.362000 | 0.008960 | 0.032100 | 5.09e-01 | -2.01e-01 | 4.49e-07 | 9.01e-01 | 6.55e-01 | 1.23e-12 | 5.05e-03 |
| ANTIMICROBIAL PEPTIDES | 13 | 2.90e-03 | 1.07e-02 | 0.6570 | 0.207000 | 0.331000 | -0.216000 | 4.47e-01 | 1.79e-01 | 1.95e-01 | 3.87e-02 | 1.77e-01 | 5.21e-03 | 2.64e-01 |
| REGULATION OF RUNX3 EXPRESSION AND ACTIVITY | 53 | 4.79e-13 | 1.38e-11 | 0.6560 | -0.392000 | -0.027800 | 0.004050 | 4.99e-01 | -1.65e-01 | 7.87e-07 | 7.27e-01 | 9.59e-01 | 3.31e-10 | 3.74e-02 |
| METABOLISM OF POLYAMINES | 56 | 3.32e-14 | 1.12e-12 | 0.6560 | -0.307000 | 0.027500 | 0.033700 | 5.71e-01 | -9.31e-02 | 7.23e-05 | 7.22e-01 | 6.63e-01 | 1.45e-13 | 2.28e-01 |
| SEROTONIN NEUROTRANSMITTER RELEASE CYCLE | 18 | 9.04e-04 | 4.01e-03 | 0.6550 | 0.348000 | -0.167000 | 0.449000 | -2.78e-01 | 3.38e-02 | 1.05e-02 | 2.19e-01 | 9.85e-04 | 4.09e-02 | 8.04e-01 |
| DEGRADATION OF DVL | 55 | 1.06e-13 | 3.39e-12 | 0.6550 | -0.387000 | -0.037000 | 0.044400 | 4.94e-01 | -1.78e-01 | 6.90e-07 | 6.35e-01 | 5.69e-01 | 2.33e-10 | 2.24e-02 |
| DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS | 18 | 4.16e-03 | 1.41e-02 | 0.6530 | 0.133000 | 0.175000 | 0.440000 | 3.14e-01 | 2.93e-01 | 3.28e-01 | 1.98e-01 | 1.23e-03 | 2.13e-02 | 3.12e-02 |
| VOLTAGE GATED POTASSIUM CHANNELS | 39 | 9.19e-07 | 8.68e-06 | 0.6510 | 0.425000 | -0.077900 | 0.355000 | -2.04e-01 | 2.65e-01 | 4.34e-06 | 4.00e-01 | 1.27e-04 | 2.78e-02 | 4.27e-03 |
| DETOXIFICATION OF REACTIVE OXYGEN SPECIES | 31 | 6.48e-06 | 5.01e-05 | 0.6500 | -0.340000 | 0.205000 | -0.132000 | 4.57e-01 | -1.98e-01 | 1.06e-03 | 4.87e-02 | 2.04e-01 | 1.05e-05 | 5.70e-02 |
| RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE | 20 | 8.74e-04 | 3.90e-03 | 0.6500 | -0.364000 | 0.114000 | -0.147000 | 4.53e-01 | -2.23e-01 | 4.86e-03 | 3.78e-01 | 2.56e-01 | 4.51e-04 | 8.37e-02 |
| NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | 21 | 7.70e-04 | 3.53e-03 | 0.6490 | 0.491000 | -0.088200 | 0.343000 | -2.05e-01 | 1.15e-01 | 9.89e-05 | 4.84e-01 | 6.49e-03 | 1.03e-01 | 3.64e-01 |
| TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX | 12 | 2.38e-02 | 5.78e-02 | 0.6480 | 0.046200 | 0.135000 | 0.451000 | 3.53e-01 | 2.68e-01 | 7.82e-01 | 4.18e-01 | 6.80e-03 | 3.42e-02 | 1.08e-01 |
| SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL | 13 | 7.61e-03 | 2.34e-02 | 0.6470 | 0.233000 | 0.314000 | -0.022600 | -2.48e-01 | 4.51e-01 | 1.45e-01 | 5.02e-02 | 8.88e-01 | 1.22e-01 | 4.84e-03 |
| SHC MEDIATED CASCADE FGFR4 | 10 | 2.40e-02 | 5.79e-02 | 0.6450 | -0.221000 | -0.113000 | -0.552000 | -2.50e-05 | 2.24e-01 | 2.26e-01 | 5.36e-01 | 2.51e-03 | 1.00e+00 | 2.21e-01 |
| HSF1 DEPENDENT TRANSACTIVATION | 33 | 7.73e-05 | 4.54e-04 | 0.6440 | -0.292000 | -0.324000 | -0.193000 | -2.77e-01 | -3.33e-01 | 3.75e-03 | 1.28e-03 | 5.51e-02 | 5.98e-03 | 9.34e-04 |
| REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | 15 | 1.36e-02 | 3.75e-02 | 0.6440 | 0.275000 | 0.239000 | 0.068500 | 9.51e-02 | 5.17e-01 | 6.51e-02 | 1.08e-01 | 6.46e-01 | 5.24e-01 | 5.25e-04 |
| CITRIC ACID CYCLE TCA CYCLE | 22 | 1.01e-04 | 5.80e-04 | 0.6420 | 0.027500 | 0.200000 | 0.053800 | 4.49e-01 | 4.08e-01 | 8.24e-01 | 1.05e-01 | 6.62e-01 | 2.63e-04 | 9.27e-04 |
| DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS | 58 | 5.80e-13 | 1.57e-11 | 0.6390 | -0.382000 | 0.006550 | 0.000855 | 4.78e-01 | -1.86e-01 | 4.90e-07 | 9.31e-01 | 9.91e-01 | 3.08e-10 | 1.43e-02 |
| COHESIN LOADING ONTO CHROMATIN | 10 | 8.39e-02 | 1.55e-01 | 0.6380 | 0.049700 | -0.254000 | -0.187000 | -5.39e-01 | 1.20e-01 | 7.85e-01 | 1.64e-01 | 3.05e-01 | 3.16e-03 | 5.10e-01 |
| NEUREXINS AND NEUROLIGINS | 54 | 1.11e-10 | 2.03e-09 | 0.6370 | 0.300000 | -0.279000 | 0.280000 | -3.82e-01 | 1.16e-01 | 1.39e-04 | 3.88e-04 | 3.81e-04 | 1.18e-06 | 1.41e-01 |
| RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES | 20 | 7.20e-04 | 3.34e-03 | 0.6360 | 0.080200 | -0.278000 | 0.098100 | -4.99e-01 | 2.48e-01 | 5.35e-01 | 3.12e-02 | 4.48e-01 | 1.11e-04 | 5.47e-02 |
| IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | 10 | 2.64e-02 | 6.22e-02 | 0.6350 | 0.285000 | -0.340000 | 0.329000 | -1.96e-01 | -2.43e-01 | 1.19e-01 | 6.23e-02 | 7.15e-02 | 2.82e-01 | 1.84e-01 |
| FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | 19 | 1.04e-03 | 4.56e-03 | 0.6340 | -0.449000 | -0.215000 | -0.083400 | 2.82e-01 | -2.60e-01 | 7.00e-04 | 1.05e-01 | 5.29e-01 | 3.33e-02 | 5.00e-02 |
| ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS | 10 | 5.54e-02 | 1.12e-01 | 0.6330 | 0.050200 | -0.369000 | 0.181000 | -4.75e-01 | 6.05e-02 | 7.83e-01 | 4.34e-02 | 3.21e-01 | 9.23e-03 | 7.40e-01 |
| TRAFFICKING OF AMPA RECEPTORS | 31 | 2.21e-05 | 1.47e-04 | 0.6320 | 0.410000 | -0.093600 | 0.436000 | -1.31e-01 | 1.27e-01 | 7.82e-05 | 3.67e-01 | 2.71e-05 | 2.05e-01 | 2.19e-01 |
| PKA ACTIVATION IN GLUCAGON SIGNALLING | 16 | 2.12e-03 | 8.33e-03 | 0.6320 | -0.025200 | -0.255000 | 0.130000 | -5.51e-01 | 1.16e-01 | 8.61e-01 | 7.76e-02 | 3.68e-01 | 1.35e-04 | 4.20e-01 |
| MET ACTIVATES RAP1 AND RAC1 | 10 | 1.53e-01 | 2.40e-01 | 0.6320 | -0.248000 | -0.399000 | -0.309000 | -2.88e-01 | -1.26e-02 | 1.75e-01 | 2.88e-02 | 9.12e-02 | 1.15e-01 | 9.45e-01 |
| AMINE LIGAND BINDING RECEPTORS | 28 | 5.79e-06 | 4.50e-05 | 0.6310 | 0.238000 | 0.040100 | 0.286000 | -4.43e-01 | 2.51e-01 | 2.95e-02 | 7.14e-01 | 8.87e-03 | 5.01e-05 | 2.17e-02 |
| BRANCHED CHAIN AMINO ACID CATABOLISM | 21 | 1.65e-04 | 9.12e-04 | 0.6310 | -0.099600 | 0.327000 | -0.074200 | 2.99e-01 | 4.31e-01 | 4.29e-01 | 9.45e-03 | 5.56e-01 | 1.77e-02 | 6.22e-04 |
| SIGNALING BY ROBO RECEPTORS | 204 | 1.06e-40 | 7.18e-39 | 0.6270 | -0.333000 | 0.026200 | -0.045900 | 3.92e-01 | -3.55e-01 | 2.32e-16 | 5.19e-01 | 2.60e-01 | 5.37e-22 | 2.23e-18 |
| SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER | 15 | 5.00e-03 | 1.66e-02 | 0.6270 | -0.268000 | -0.156000 | 0.015100 | -3.28e-01 | -4.35e-01 | 7.25e-02 | 2.94e-01 | 9.19e-01 | 2.79e-02 | 3.51e-03 |
| SIGNALING BY FGFR4 IN DISEASE | 10 | 1.91e-01 | 2.82e-01 | 0.6230 | -0.207000 | -0.428000 | -0.269000 | -2.66e-01 | -1.39e-01 | 2.57e-01 | 1.91e-02 | 1.41e-01 | 1.45e-01 | 4.46e-01 |
| MITOCHONDRIAL FATTY ACID BETA OXIDATION | 33 | 1.51e-06 | 1.38e-05 | 0.6230 | -0.089100 | 0.392000 | -0.214000 | 4.16e-01 | 9.12e-02 | 3.76e-01 | 9.78e-05 | 3.36e-02 | 3.59e-05 | 3.65e-01 |
| INHIBITION OF DNA RECOMBINATION AT TELOMERE | 33 | 4.70e-06 | 3.71e-05 | 0.6220 | -0.263000 | 0.093900 | -0.098900 | 4.71e-01 | -2.78e-01 | 8.92e-03 | 3.51e-01 | 3.25e-01 | 2.85e-06 | 5.65e-03 |
| SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | 15 | 1.42e-02 | 3.86e-02 | 0.6200 | 0.249000 | -0.014700 | 0.349000 | -2.69e-01 | 3.58e-01 | 9.55e-02 | 9.22e-01 | 1.94e-02 | 7.08e-02 | 1.63e-02 |
| PROCESSING OF SMDT1 | 16 | 9.31e-03 | 2.78e-02 | 0.6200 | -0.019600 | 0.310000 | -0.005890 | 5.34e-01 | 5.61e-02 | 8.92e-01 | 3.19e-02 | 9.67e-01 | 2.19e-04 | 6.98e-01 |
| DEGRADATION OF AXIN | 53 | 5.62e-11 | 1.10e-09 | 0.6170 | -0.381000 | 0.015600 | 0.000221 | 4.58e-01 | -1.60e-01 | 1.56e-06 | 8.44e-01 | 9.98e-01 | 8.27e-09 | 4.44e-02 |
| EFFECTS OF PIP2 HYDROLYSIS | 27 | 3.00e-04 | 1.55e-03 | 0.6140 | 0.417000 | -0.166000 | 0.250000 | -1.52e-01 | 3.00e-01 | 1.78e-04 | 1.35e-01 | 2.48e-02 | 1.71e-01 | 6.89e-03 |
| ASPARTATE AND ASPARAGINE METABOLISM | 11 | 8.22e-02 | 1.52e-01 | 0.6100 | 0.140000 | 0.333000 | 0.075300 | 1.26e-01 | 4.69e-01 | 4.23e-01 | 5.55e-02 | 6.65e-01 | 4.68e-01 | 7.09e-03 |
| RETROGRADE NEUROTROPHIN SIGNALLING | 12 | 5.98e-02 | 1.20e-01 | 0.6100 | 0.207000 | 0.168000 | 0.446000 | -7.89e-02 | 3.09e-01 | 2.14e-01 | 3.14e-01 | 7.50e-03 | 6.36e-01 | 6.37e-02 |
| LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME | 13 | 1.48e-02 | 3.96e-02 | 0.6080 | 0.105000 | -0.458000 | 0.273000 | -2.61e-01 | -7.86e-02 | 5.14e-01 | 4.29e-03 | 8.81e-02 | 1.03e-01 | 6.24e-01 |
| SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | 14 | 7.37e-03 | 2.28e-02 | 0.6070 | 0.025300 | -0.439000 | 0.157000 | -2.55e-01 | 2.91e-01 | 8.70e-01 | 4.43e-03 | 3.08e-01 | 9.90e-02 | 5.94e-02 |
| NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 | 11 | 4.17e-02 | 9.01e-02 | 0.6050 | 0.070100 | -0.082200 | -0.401000 | -4.07e-01 | 1.68e-01 | 6.87e-01 | 6.37e-01 | 2.13e-02 | 1.94e-02 | 3.35e-01 |
| SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | 16 | 7.70e-03 | 2.36e-02 | 0.6040 | 0.179000 | -0.012100 | 0.035400 | -3.88e-01 | 4.26e-01 | 2.14e-01 | 9.33e-01 | 8.07e-01 | 7.28e-03 | 3.21e-03 |
| G PROTEIN ACTIVATION | 21 | 1.41e-03 | 5.75e-03 | 0.6030 | -0.377000 | -0.237000 | 0.020200 | 1.36e-01 | -3.83e-01 | 2.81e-03 | 6.05e-02 | 8.73e-01 | 2.79e-01 | 2.36e-03 |
| RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS | 80 | 6.68e-14 | 2.20e-12 | 0.6020 | -0.375000 | 0.055900 | -0.129000 | 3.88e-01 | -2.27e-01 | 6.70e-09 | 3.88e-01 | 4.57e-02 | 2.09e-09 | 4.61e-04 |
| PYROPTOSIS | 20 | 1.20e-03 | 5.05e-03 | 0.5970 | -0.285000 | 0.023200 | 0.025900 | 4.90e-01 | -1.85e-01 | 2.74e-02 | 8.57e-01 | 8.41e-01 | 1.49e-04 | 1.51e-01 |
| ASSEMBLY OF THE PRE REPLICATIVE COMPLEX | 64 | 5.87e-13 | 1.57e-11 | 0.5970 | -0.294000 | 0.054600 | 0.072000 | 5.02e-01 | -9.72e-02 | 4.77e-05 | 4.50e-01 | 3.20e-01 | 3.71e-12 | 1.79e-01 |
| FORMATION OF THE EARLY ELONGATION COMPLEX | 33 | 1.04e-05 | 7.64e-05 | 0.5960 | -0.155000 | 0.177000 | 0.276000 | 4.37e-01 | -1.81e-01 | 1.25e-01 | 7.85e-02 | 6.01e-03 | 1.38e-05 | 7.20e-02 |
| DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING | 58 | 1.81e-11 | 4.01e-10 | 0.5960 | -0.325000 | 0.007530 | 0.013700 | 4.76e-01 | -1.51e-01 | 1.92e-05 | 9.21e-01 | 8.57e-01 | 3.65e-10 | 4.73e-02 |
| APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | 70 | 2.02e-13 | 6.30e-12 | 0.5930 | -0.343000 | 0.067900 | 0.030500 | 4.60e-01 | -1.31e-01 | 6.93e-07 | 3.26e-01 | 6.60e-01 | 2.79e-11 | 5.91e-02 |
| HEDGEHOG LIGAND BIOGENESIS | 61 | 4.92e-11 | 1.00e-09 | 0.5930 | -0.400000 | -0.002100 | -0.040600 | 3.86e-01 | -2.04e-01 | 6.59e-08 | 9.77e-01 | 5.83e-01 | 1.89e-07 | 5.87e-03 |
| CONSTITUTIVE SIGNALING BY EGFRVIII | 15 | 8.43e-02 | 1.55e-01 | 0.5930 | -0.218000 | -0.368000 | -0.277000 | -2.21e-01 | -2.08e-01 | 1.43e-01 | 1.37e-02 | 6.30e-02 | 1.38e-01 | 1.64e-01 |
| PROTEIN PROTEIN INTERACTIONS AT SYNAPSES | 85 | 4.17e-15 | 1.55e-13 | 0.5920 | 0.227000 | -0.234000 | 0.262000 | -3.91e-01 | 1.50e-01 | 2.94e-04 | 1.91e-04 | 3.06e-05 | 4.60e-10 | 1.72e-02 |
| SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS | 15 | 2.74e-03 | 1.02e-02 | 0.5920 | -0.161000 | -0.131000 | 0.000706 | -3.99e-01 | 3.85e-01 | 2.81e-01 | 3.78e-01 | 9.96e-01 | 7.52e-03 | 9.88e-03 |
| DEGRADATION OF GLI1 BY THE PROTEASOME | 57 | 7.04e-11 | 1.31e-09 | 0.5910 | -0.365000 | 0.014600 | -0.010500 | 4.43e-01 | -1.42e-01 | 1.90e-06 | 8.49e-01 | 8.91e-01 | 7.44e-09 | 6.32e-02 |
| RORA ACTIVATES GENE EXPRESSION | 18 | 8.13e-03 | 2.47e-02 | 0.5910 | 0.313000 | -0.285000 | -0.032600 | -3.81e-01 | 1.53e-01 | 2.16e-02 | 3.60e-02 | 8.11e-01 | 5.17e-03 | 2.62e-01 |
| APOPTOSIS INDUCED DNA FRAGMENTATION | 10 | 4.86e-02 | 1.02e-01 | 0.5890 | 0.103000 | 0.401000 | -0.267000 | 1.36e-01 | 2.92e-01 | 5.72e-01 | 2.83e-02 | 1.43e-01 | 4.56e-01 | 1.10e-01 |
| REGULATION OF MECP2 EXPRESSION AND ACTIVITY | 29 | 1.30e-04 | 7.36e-04 | 0.5870 | 0.190000 | -0.338000 | 0.117000 | -4.25e-01 | -1.68e-02 | 7.60e-02 | 1.65e-03 | 2.75e-01 | 7.36e-05 | 8.76e-01 |
| DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | 23 | 6.23e-04 | 2.94e-03 | 0.5870 | 0.280000 | -0.228000 | 0.376000 | -2.69e-01 | 3.23e-02 | 2.02e-02 | 5.86e-02 | 1.79e-03 | 2.58e-02 | 7.89e-01 |
| RRNA PROCESSING IN THE MITOCHONDRION | 10 | 9.35e-02 | 1.68e-01 | 0.5870 | 0.023500 | 0.093100 | 0.359000 | 3.61e-01 | 2.76e-01 | 8.97e-01 | 6.10e-01 | 4.91e-02 | 4.80e-02 | 1.31e-01 |
| PURINE SALVAGE | 12 | 2.98e-02 | 6.87e-02 | 0.5860 | -0.261000 | 0.194000 | 0.190000 | 4.28e-01 | 1.36e-01 | 1.18e-01 | 2.46e-01 | 2.54e-01 | 1.03e-02 | 4.14e-01 |
| METABOLISM OF AMINO ACIDS AND DERIVATIVES | 304 | 5.08e-58 | 7.31e-56 | 0.5860 | -0.244000 | 0.138000 | -0.079800 | 5.01e-01 | -8.52e-02 | 3.01e-13 | 3.46e-05 | 1.71e-02 | 4.48e-51 | 1.08e-02 |
| MRNA SPLICING MINOR PATHWAY | 52 | 4.20e-09 | 6.21e-08 | 0.5830 | -0.280000 | 0.101000 | 0.152000 | 3.22e-01 | -3.54e-01 | 4.77e-04 | 2.07e-01 | 5.86e-02 | 6.03e-05 | 1.03e-05 |
| CHEMOKINE RECEPTORS BIND CHEMOKINES | 12 | 8.58e-02 | 1.57e-01 | 0.5830 | -0.121000 | -0.318000 | -0.056000 | -1.98e-01 | -4.26e-01 | 4.68e-01 | 5.65e-02 | 7.37e-01 | 2.36e-01 | 1.07e-02 |
| LGI ADAM INTERACTIONS | 14 | 2.75e-02 | 6.42e-02 | 0.5800 | 0.342000 | -0.121000 | 0.452000 | -3.17e-02 | -1.24e-02 | 2.68e-02 | 4.33e-01 | 3.43e-03 | 8.37e-01 | 9.36e-01 |
| SIGNALING BY FGFR3 FUSIONS IN CANCER | 10 | 1.98e-01 | 2.90e-01 | 0.5790 | -0.213000 | -0.293000 | -0.405000 | -1.97e-01 | 3.06e-02 | 2.42e-01 | 1.08e-01 | 2.65e-02 | 2.82e-01 | 8.67e-01 |
| MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS | 18 | 8.64e-03 | 2.61e-02 | 0.5790 | 0.309000 | -0.246000 | 0.213000 | -3.64e-01 | 4.63e-02 | 2.34e-02 | 7.10e-02 | 1.19e-01 | 7.55e-03 | 7.34e-01 |
| GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 12 | 1.30e-01 | 2.13e-01 | 0.5790 | -0.308000 | -0.330000 | -0.156000 | -3.09e-01 | -1.02e-01 | 6.43e-02 | 4.76e-02 | 3.49e-01 | 6.35e-02 | 5.42e-01 |
| RHOBTB GTPASE CYCLE | 35 | 6.29e-04 | 2.96e-03 | 0.5760 | -0.318000 | -0.287000 | -0.208000 | -2.05e-01 | -2.52e-01 | 1.14e-03 | 3.36e-03 | 3.35e-02 | 3.56e-02 | 9.92e-03 |
| NUCLEOTIDE LIKE PURINERGIC RECEPTORS | 12 | 1.38e-01 | 2.23e-01 | 0.5760 | -0.220000 | -0.123000 | -0.440000 | -2.24e-01 | -1.56e-01 | 1.87e-01 | 4.62e-01 | 8.31e-03 | 1.79e-01 | 3.50e-01 |
| STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES | 14 | 1.18e-01 | 2.01e-01 | 0.5740 | -0.154000 | -0.290000 | -0.286000 | -2.68e-01 | -2.60e-01 | 3.18e-01 | 6.04e-02 | 6.36e-02 | 8.26e-02 | 9.22e-02 |
| SODIUM CALCIUM EXCHANGERS | 10 | 1.52e-01 | 2.40e-01 | 0.5740 | 0.257000 | -0.127000 | 0.180000 | -3.86e-01 | 2.56e-01 | 1.60e-01 | 4.87e-01 | 3.25e-01 | 3.44e-02 | 1.61e-01 |
| FGFR2 ALTERNATIVE SPLICING | 25 | 5.67e-04 | 2.71e-03 | 0.5720 | -0.208000 | -0.055100 | 0.023000 | 2.82e-01 | -4.48e-01 | 7.22e-02 | 6.34e-01 | 8.42e-01 | 1.46e-02 | 1.07e-04 |
| SIGNALING BY FGFR2 IIIA TM | 19 | 3.78e-03 | 1.31e-02 | 0.5710 | -0.099700 | 0.078000 | 0.010400 | 4.82e-01 | -2.79e-01 | 4.52e-01 | 5.56e-01 | 9.37e-01 | 2.77e-04 | 3.54e-02 |
| REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA | 13 | 1.28e-01 | 2.11e-01 | 0.5710 | -0.383000 | -0.212000 | -0.148000 | -3.25e-02 | -3.33e-01 | 1.67e-02 | 1.86e-01 | 3.54e-01 | 8.39e-01 | 3.76e-02 |
| AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS | 10 | 1.27e-01 | 2.10e-01 | 0.5700 | 0.159000 | -0.478000 | 0.016300 | -2.62e-01 | -4.47e-02 | 3.83e-01 | 8.84e-03 | 9.29e-01 | 1.52e-01 | 8.07e-01 |
| ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 | 19 | 1.09e-02 | 3.14e-02 | 0.5700 | -0.365000 | 0.184000 | -0.277000 | 2.52e-01 | -1.32e-01 | 5.91e-03 | 1.65e-01 | 3.69e-02 | 5.70e-02 | 3.18e-01 |
| INTERFERON ALPHA BETA SIGNALING | 53 | 2.30e-07 | 2.52e-06 | 0.5700 | -0.150000 | -0.298000 | -0.308000 | -1.08e-02 | -3.44e-01 | 5.84e-02 | 1.73e-04 | 1.08e-04 | 8.92e-01 | 1.51e-05 |
| ERYTHROPOIETIN ACTIVATES RAS | 13 | 2.41e-02 | 5.79e-02 | 0.5680 | -0.118000 | -0.436000 | -0.231000 | -1.17e-01 | 2.27e-01 | 4.61e-01 | 6.47e-03 | 1.49e-01 | 4.66e-01 | 1.57e-01 |
| G1 S DNA DAMAGE CHECKPOINTS | 64 | 1.89e-11 | 4.12e-10 | 0.5680 | -0.316000 | -0.009870 | -0.051100 | 4.48e-01 | -1.40e-01 | 1.27e-05 | 8.91e-01 | 4.80e-01 | 5.76e-10 | 5.34e-02 |
| PINK1 PRKN MEDIATED MITOPHAGY | 22 | 7.20e-04 | 3.34e-03 | 0.5680 | -0.213000 | 0.025500 | 0.070500 | 5.11e-01 | -9.99e-02 | 8.34e-02 | 8.36e-01 | 5.67e-01 | 3.34e-05 | 4.17e-01 |
| WNT5A DEPENDENT INTERNALIZATION OF FZD4 | 15 | 2.75e-02 | 6.42e-02 | 0.5660 | 0.193000 | -0.015700 | 0.506000 | -1.55e-02 | 1.63e-01 | 1.95e-01 | 9.16e-01 | 6.92e-04 | 9.17e-01 | 2.73e-01 |
| SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION | 22 | 3.44e-03 | 1.22e-02 | 0.5640 | -0.286000 | 0.123000 | -0.335000 | 2.95e-01 | -1.50e-01 | 2.04e-02 | 3.17e-01 | 6.49e-03 | 1.67e-02 | 2.24e-01 |
| PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | 16 | 1.52e-02 | 4.05e-02 | 0.5630 | -0.369000 | -0.095100 | 0.037000 | 3.09e-01 | -2.74e-01 | 1.06e-02 | 5.10e-01 | 7.98e-01 | 3.23e-02 | 5.75e-02 |
| REGULATION OF HMOX1 EXPRESSION AND ACTIVITY | 63 | 2.18e-10 | 3.69e-09 | 0.5630 | -0.312000 | 0.074500 | -0.004310 | 4.42e-01 | -1.37e-01 | 1.90e-05 | 3.07e-01 | 9.53e-01 | 1.32e-09 | 6.08e-02 |
| SIGNALING BY BMP | 25 | 2.15e-03 | 8.42e-03 | 0.5620 | -0.095100 | -0.197000 | -0.260000 | -4.35e-01 | 1.07e-01 | 4.10e-01 | 8.87e-02 | 2.42e-02 | 1.67e-04 | 3.57e-01 |
| CONDENSATION OF PROPHASE CHROMOSOMES | 25 | 1.38e-03 | 5.66e-03 | 0.5610 | -0.304000 | 0.133000 | -0.377000 | 2.22e-01 | -1.13e-01 | 8.44e-03 | 2.51e-01 | 1.10e-03 | 5.43e-02 | 3.26e-01 |
| DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX | 41 | 1.23e-05 | 8.76e-05 | 0.5600 | -0.197000 | -0.152000 | -0.203000 | -4.21e-01 | -1.82e-01 | 2.90e-02 | 9.13e-02 | 2.49e-02 | 3.06e-06 | 4.36e-02 |
| GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION | 11 | 1.17e-01 | 1.99e-01 | 0.5590 | 0.137000 | 0.055800 | 0.280000 | 2.56e-01 | 3.84e-01 | 4.32e-01 | 7.49e-01 | 1.08e-01 | 1.42e-01 | 2.75e-02 |
| PI 3K CASCADE FGFR4 | 10 | 9.71e-02 | 1.73e-01 | 0.5590 | -0.034000 | -0.093000 | -0.501000 | -1.90e-01 | 1.26e-01 | 8.52e-01 | 6.11e-01 | 6.10e-03 | 2.97e-01 | 4.89e-01 |
| HEME SIGNALING | 44 | 3.77e-06 | 3.08e-05 | 0.5590 | 0.271000 | -0.267000 | 0.117000 | -3.59e-01 | 1.61e-01 | 1.90e-03 | 2.15e-03 | 1.81e-01 | 3.87e-05 | 6.48e-02 |
| ORC1 REMOVAL FROM CHROMATIN | 66 | 4.95e-11 | 1.00e-09 | 0.5560 | -0.311000 | 0.067300 | 0.014500 | 4.44e-01 | -1.05e-01 | 1.26e-05 | 3.45e-01 | 8.39e-01 | 4.50e-10 | 1.40e-01 |
| RHOBTB3 ATPASE CYCLE | 10 | 3.96e-02 | 8.69e-02 | 0.5560 | -0.314000 | 0.113000 | -0.213000 | -9.32e-02 | 3.79e-01 | 8.53e-02 | 5.36e-01 | 2.44e-01 | 6.10e-01 | 3.81e-02 |
| DSCAM INTERACTIONS | 10 | 1.28e-01 | 2.11e-01 | 0.5550 | 0.304000 | -0.273000 | 0.343000 | -1.52e-01 | 1.57e-02 | 9.55e-02 | 1.35e-01 | 6.05e-02 | 4.05e-01 | 9.31e-01 |
| CALNEXIN CALRETICULIN CYCLE | 26 | 5.00e-03 | 1.66e-02 | 0.5550 | -0.365000 | -0.286000 | -0.229000 | -1.87e-01 | -7.28e-02 | 1.27e-03 | 1.17e-02 | 4.30e-02 | 9.85e-02 | 5.21e-01 |
| ERK MAPK TARGETS | 22 | 3.85e-03 | 1.33e-02 | 0.5540 | 0.220000 | -0.229000 | 0.262000 | -1.98e-01 | 3.13e-01 | 7.46e-02 | 6.29e-02 | 3.31e-02 | 1.08e-01 | 1.10e-02 |
| CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 | 11 | 1.43e-01 | 2.29e-01 | 0.5530 | -0.308000 | -0.284000 | -0.361000 | -6.12e-03 | 1.03e-02 | 7.68e-02 | 1.03e-01 | 3.84e-02 | 9.72e-01 | 9.53e-01 |
| RNA POLYMERASE I PROMOTER ESCAPE | 45 | 3.07e-06 | 2.57e-05 | 0.5530 | -0.293000 | 0.138000 | -0.050800 | 3.89e-01 | -2.15e-01 | 6.61e-04 | 1.09e-01 | 5.56e-01 | 6.29e-06 | 1.26e-02 |
| ANTIGEN PROCESSING CROSS PRESENTATION | 91 | 5.24e-15 | 1.89e-13 | 0.5520 | -0.305000 | -0.051400 | -0.185000 | 3.85e-01 | -1.64e-01 | 4.97e-07 | 3.97e-01 | 2.32e-03 | 2.18e-10 | 6.96e-03 |
| DEGRADATION OF CYSTEINE AND HOMOCYSTEINE | 13 | 2.51e-02 | 5.98e-02 | 0.5510 | -0.075000 | 0.134000 | -0.006940 | 3.71e-01 | 3.77e-01 | 6.40e-01 | 4.04e-01 | 9.65e-01 | 2.05e-02 | 1.85e-02 |
| CHOLESTEROL BIOSYNTHESIS | 24 | 2.06e-04 | 1.11e-03 | 0.5500 | -0.487000 | -0.216000 | 0.008680 | -1.25e-01 | -5.51e-02 | 3.58e-05 | 6.69e-02 | 9.41e-01 | 2.91e-01 | 6.41e-01 |
| SIGNALING BY ERBB2 ECD MUTANTS | 16 | 1.23e-01 | 2.06e-01 | 0.5480 | -0.265000 | -0.304000 | -0.269000 | -1.81e-01 | -1.80e-01 | 6.63e-02 | 3.52e-02 | 6.24e-02 | 2.11e-01 | 2.13e-01 |
| PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR | 20 | 1.10e-02 | 3.15e-02 | 0.5470 | -0.167000 | 0.214000 | 0.120000 | 4.57e-01 | -5.19e-02 | 1.97e-01 | 9.82e-02 | 3.52e-01 | 4.03e-04 | 6.88e-01 |
| UNWINDING OF DNA | 12 | 1.92e-01 | 2.82e-01 | 0.5470 | 0.113000 | 0.243000 | 0.250000 | 2.72e-01 | 3.01e-01 | 4.97e-01 | 1.45e-01 | 1.34e-01 | 1.03e-01 | 7.10e-02 |
| ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | 22 | 2.80e-02 | 6.51e-02 | 0.5450 | -0.337000 | -0.223000 | -0.293000 | -1.92e-01 | -1.04e-01 | 6.23e-03 | 6.96e-02 | 1.74e-02 | 1.20e-01 | 4.00e-01 |
| MISCELLANEOUS TRANSPORT AND BINDING EVENTS | 20 | 1.45e-02 | 3.91e-02 | 0.5440 | 0.296000 | -0.186000 | 0.028700 | -3.20e-01 | 2.67e-01 | 2.21e-02 | 1.50e-01 | 8.24e-01 | 1.33e-02 | 3.90e-02 |
| NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS | 10 | 4.61e-02 | 9.77e-02 | 0.5440 | -0.045800 | 0.169000 | 0.012000 | -3.89e-01 | 3.37e-01 | 8.02e-01 | 3.54e-01 | 9.48e-01 | 3.34e-02 | 6.50e-02 |
| CELLULAR RESPONSE TO HYPOXIA | 71 | 4.32e-11 | 9.05e-10 | 0.5430 | -0.322000 | 0.025600 | -0.018500 | 4.08e-01 | -1.53e-01 | 2.71e-06 | 7.09e-01 | 7.87e-01 | 2.74e-09 | 2.54e-02 |
| COMPLEMENT CASCADE | 23 | 1.65e-05 | 1.14e-04 | 0.5430 | 0.186000 | 0.247000 | -0.399000 | 1.58e-01 | -1.22e-01 | 1.22e-01 | 4.02e-02 | 9.29e-04 | 1.89e-01 | 3.13e-01 |
| INTERLEUKIN 6 SIGNALING | 10 | 1.49e-01 | 2.37e-01 | 0.5420 | 0.294000 | -0.263000 | -0.143000 | -2.70e-01 | 2.11e-01 | 1.08e-01 | 1.51e-01 | 4.32e-01 | 1.39e-01 | 2.47e-01 |
| GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION | 31 | 2.85e-04 | 1.48e-03 | 0.5420 | -0.306000 | 0.084700 | -0.082400 | 4.03e-01 | -1.52e-01 | 3.17e-03 | 4.14e-01 | 4.27e-01 | 1.02e-04 | 1.44e-01 |
| G PROTEIN MEDIATED EVENTS | 51 | 5.24e-07 | 5.39e-06 | 0.5410 | 0.157000 | -0.227000 | 0.115000 | -3.72e-01 | 2.55e-01 | 5.28e-02 | 5.10e-03 | 1.57e-01 | 4.35e-06 | 1.63e-03 |
| FCGR3A MEDIATED IL10 SYNTHESIS | 32 | 4.51e-04 | 2.25e-03 | 0.5390 | -0.051600 | -0.292000 | -0.114000 | -4.02e-01 | 1.68e-01 | 6.13e-01 | 4.27e-03 | 2.66e-01 | 8.28e-05 | 9.93e-02 |
| SEMA3A PAK DEPENDENT AXON REPULSION | 16 | 3.89e-02 | 8.59e-02 | 0.5390 | -0.140000 | -0.401000 | -0.003780 | -3.30e-01 | 4.04e-02 | 3.34e-01 | 5.45e-03 | 9.79e-01 | 2.25e-02 | 7.80e-01 |
| OLFACTORY SIGNALING PATHWAY | 22 | 1.43e-04 | 7.98e-04 | 0.5390 | 0.152000 | -0.098200 | -0.298000 | -3.31e-02 | -4.10e-01 | 2.17e-01 | 4.26e-01 | 1.54e-02 | 7.88e-01 | 8.82e-04 |
| CELLULAR HEXOSE TRANSPORT | 10 | 3.32e-01 | 4.28e-01 | 0.5360 | 0.214000 | 0.213000 | 0.330000 | 3.23e-02 | 2.94e-01 | 2.42e-01 | 2.45e-01 | 7.06e-02 | 8.60e-01 | 1.08e-01 |
| BETA CATENIN PHOSPHORYLATION CASCADE | 16 | 5.92e-03 | 1.90e-02 | 0.5350 | -0.118000 | -0.094900 | 0.058900 | -3.44e-01 | 3.76e-01 | 4.14e-01 | 5.11e-01 | 6.83e-01 | 1.71e-02 | 9.20e-03 |
| GP1B IX V ACTIVATION SIGNALLING | 10 | 1.83e-01 | 2.74e-01 | 0.5330 | 0.275000 | 0.338000 | 0.259000 | -1.14e-01 | 1.18e-01 | 1.33e-01 | 6.41e-02 | 1.56e-01 | 5.31e-01 | 5.17e-01 |
| CROSSLINKING OF COLLAGEN FIBRILS | 14 | 4.14e-02 | 8.96e-02 | 0.5330 | 0.270000 | 0.137000 | 0.392000 | -1.95e-01 | 3.98e-03 | 7.98e-02 | 3.76e-01 | 1.11e-02 | 2.06e-01 | 9.79e-01 |
| THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | 21 | 3.46e-03 | 1.22e-02 | 0.5320 | -0.322000 | -0.262000 | 0.030500 | 2.11e-01 | -2.57e-01 | 1.07e-02 | 3.79e-02 | 8.09e-01 | 9.48e-02 | 4.15e-02 |
| MITOTIC TELOPHASE CYTOKINESIS | 13 | 1.11e-01 | 1.92e-01 | 0.5300 | 0.064100 | -0.201000 | -0.131000 | -4.69e-01 | 2.89e-03 | 6.89e-01 | 2.10e-01 | 4.13e-01 | 3.44e-03 | 9.86e-01 |
| NEPHRIN FAMILY INTERACTIONS | 21 | 1.09e-02 | 3.15e-02 | 0.5290 | 0.305000 | -0.093500 | 0.177000 | -3.62e-01 | 1.27e-01 | 1.56e-02 | 4.58e-01 | 1.60e-01 | 4.09e-03 | 3.14e-01 |
| GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | 23 | 2.66e-03 | 1.00e-02 | 0.5290 | 0.290000 | -0.306000 | 0.268000 | -7.39e-02 | 1.58e-01 | 1.60e-02 | 1.11e-02 | 2.63e-02 | 5.40e-01 | 1.91e-01 |
| TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | 11 | 8.05e-02 | 1.49e-01 | 0.5280 | -0.132000 | 0.155000 | -0.443000 | 2.04e-01 | -1.52e-02 | 4.49e-01 | 3.74e-01 | 1.10e-02 | 2.42e-01 | 9.30e-01 |
| CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | 11 | 7.24e-02 | 1.37e-01 | 0.5280 | 0.087000 | -0.103000 | 0.243000 | -4.48e-01 | 3.25e-02 | 6.17e-01 | 5.55e-01 | 1.63e-01 | 1.00e-02 | 8.52e-01 |
| INITIAL TRIGGERING OF COMPLEMENT | 10 | 2.02e-02 | 5.04e-02 | 0.5280 | 0.316000 | 0.195000 | -0.263000 | 1.42e-01 | -2.29e-01 | 8.39e-02 | 2.87e-01 | 1.50e-01 | 4.36e-01 | 2.10e-01 |
| CRMPS IN SEMA3A SIGNALING | 16 | 2.20e-02 | 5.40e-02 | 0.5280 | 0.054700 | -0.280000 | 0.250000 | -3.59e-01 | 8.00e-02 | 7.05e-01 | 5.22e-02 | 8.38e-02 | 1.30e-02 | 5.79e-01 |
| TRANSLESION SYNTHESIS BY POLK | 17 | 5.23e-02 | 1.07e-01 | 0.5260 | -0.123000 | 0.270000 | 0.080900 | 4.09e-01 | -1.23e-01 | 3.78e-01 | 5.40e-02 | 5.64e-01 | 3.54e-03 | 3.80e-01 |
| IRF3 MEDIATED INDUCTION OF TYPE I IFN | 11 | 2.78e-01 | 3.75e-01 | 0.5260 | -0.144000 | -0.172000 | -0.292000 | -2.56e-01 | -2.74e-01 | 4.08e-01 | 3.22e-01 | 9.39e-02 | 1.41e-01 | 1.15e-01 |
| DISEASES OF DNA REPAIR | 11 | 6.38e-02 | 1.26e-01 | 0.5250 | -0.226000 | -0.124000 | 0.274000 | 2.34e-02 | -3.65e-01 | 1.95e-01 | 4.75e-01 | 1.15e-01 | 8.93e-01 | 3.62e-02 |
| METABOLISM OF STEROID HORMONES | 19 | 2.12e-02 | 5.24e-02 | 0.5230 | -0.340000 | 0.066000 | -0.031200 | 3.43e-01 | -1.88e-01 | 1.04e-02 | 6.18e-01 | 8.14e-01 | 9.57e-03 | 1.57e-01 |
| GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION | 24 | 4.28e-03 | 1.44e-02 | 0.5220 | -0.067200 | 0.234000 | 0.053400 | 3.97e-01 | 2.29e-01 | 5.69e-01 | 4.68e-02 | 6.51e-01 | 7.59e-04 | 5.25e-02 |
| PIWI INTERACTING RNA PIRNA BIOGENESIS | 19 | 1.01e-02 | 2.99e-02 | 0.5200 | -0.195000 | -0.123000 | 0.051000 | 3.27e-01 | -3.29e-01 | 1.41e-01 | 3.55e-01 | 7.00e-01 | 1.37e-02 | 1.31e-02 |
| DNA REPLICATION PRE INITIATION | 78 | 5.15e-12 | 1.32e-10 | 0.5190 | -0.251000 | 0.046200 | 0.023600 | 4.47e-01 | -5.92e-02 | 1.24e-04 | 4.81e-01 | 7.18e-01 | 8.58e-12 | 3.67e-01 |
| GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | 18 | 6.36e-02 | 1.26e-01 | 0.5190 | 0.383000 | 0.216000 | 0.159000 | -4.88e-02 | 2.20e-01 | 4.96e-03 | 1.12e-01 | 2.44e-01 | 7.20e-01 | 1.07e-01 |
| SIGNALING BY ACTIVIN | 12 | 1.15e-01 | 1.97e-01 | 0.5180 | 0.121000 | -0.160000 | -0.097800 | -4.57e-01 | -1.02e-01 | 4.66e-01 | 3.38e-01 | 5.57e-01 | 6.18e-03 | 5.42e-01 |
| P38MAPK EVENTS | 12 | 3.76e-02 | 8.36e-02 | 0.5180 | -0.098300 | -0.451000 | -0.183000 | 3.52e-02 | 1.43e-01 | 5.56e-01 | 6.83e-03 | 2.73e-01 | 8.33e-01 | 3.90e-01 |
| SIGNALING BY WNT IN CANCER | 30 | 2.11e-05 | 1.42e-04 | 0.5170 | -0.084700 | 0.059900 | -0.036800 | -4.00e-01 | 3.09e-01 | 4.22e-01 | 5.70e-01 | 7.28e-01 | 1.51e-04 | 3.36e-03 |
| REGULATION OF PTEN STABILITY AND ACTIVITY | 66 | 3.31e-10 | 5.53e-09 | 0.5170 | -0.313000 | -0.072700 | -0.006810 | 3.80e-01 | -1.41e-01 | 1.13e-05 | 3.07e-01 | 9.24e-01 | 9.28e-08 | 4.79e-02 |
| OTHER SEMAPHORIN INTERACTIONS | 19 | 2.06e-02 | 5.14e-02 | 0.5170 | 0.044900 | -0.228000 | -0.054300 | -3.82e-01 | -2.53e-01 | 7.35e-01 | 8.59e-02 | 6.82e-01 | 3.95e-03 | 5.60e-02 |
| GLUCONEOGENESIS | 27 | 1.05e-03 | 4.60e-03 | 0.5170 | -0.065600 | 0.142000 | 0.224000 | 3.55e-01 | 2.57e-01 | 5.55e-01 | 2.02e-01 | 4.41e-02 | 1.40e-03 | 2.09e-02 |
| RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR | 20 | 1.70e-02 | 4.41e-02 | 0.5160 | 0.225000 | -0.257000 | 0.257000 | -1.94e-01 | 2.15e-01 | 8.18e-02 | 4.70e-02 | 4.66e-02 | 1.33e-01 | 9.57e-02 |
| NRAGE SIGNALS DEATH THROUGH JNK | 54 | 1.98e-06 | 1.77e-05 | 0.5150 | 0.227000 | -0.106000 | 0.087500 | -3.03e-01 | 3.22e-01 | 3.88e-03 | 1.79e-01 | 2.66e-01 | 1.20e-04 | 4.36e-05 |
| CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION | 11 | 1.09e-01 | 1.89e-01 | 0.5140 | 0.106000 | -0.130000 | -0.160000 | -1.43e-01 | 4.36e-01 | 5.43e-01 | 4.55e-01 | 3.57e-01 | 4.11e-01 | 1.23e-02 |
| VXPX CARGO TARGETING TO CILIUM | 19 | 2.38e-02 | 5.77e-02 | 0.5140 | 0.163000 | -0.244000 | 0.178000 | -2.74e-01 | 2.68e-01 | 2.20e-01 | 6.59e-02 | 1.78e-01 | 3.86e-02 | 4.35e-02 |
| METHYLATION | 11 | 1.46e-01 | 2.33e-01 | 0.5140 | -0.144000 | 0.223000 | -0.122000 | 4.05e-01 | 1.22e-01 | 4.09e-01 | 2.00e-01 | 4.83e-01 | 2.00e-02 | 4.85e-01 |
| MATURATION OF NUCLEOPROTEIN | 10 | 2.51e-01 | 3.49e-01 | 0.5130 | -0.230000 | -0.197000 | -0.004770 | -2.30e-01 | -3.44e-01 | 2.07e-01 | 2.82e-01 | 9.79e-01 | 2.07e-01 | 5.99e-02 |
| ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 | 19 | 3.25e-02 | 7.38e-02 | 0.5130 | -0.403000 | -0.175000 | -0.089100 | 1.22e-01 | -2.17e-01 | 2.35e-03 | 1.87e-01 | 5.02e-01 | 3.57e-01 | 1.02e-01 |
| APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS | 81 | 1.27e-11 | 2.92e-10 | 0.5120 | -0.287000 | 0.078400 | 0.042100 | 4.08e-01 | -7.48e-02 | 8.18e-06 | 2.23e-01 | 5.13e-01 | 2.28e-10 | 2.45e-01 |
| INTERLEUKIN RECEPTOR SHC SIGNALING | 20 | 2.30e-02 | 5.62e-02 | 0.5120 | -0.108000 | -0.229000 | -0.084300 | -4.32e-01 | 5.89e-02 | 4.01e-01 | 7.67e-02 | 5.14e-01 | 8.14e-04 | 6.48e-01 |
| CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS | 19 | 9.35e-02 | 1.68e-01 | 0.5110 | -0.263000 | -0.241000 | -0.202000 | -4.48e-02 | -3.01e-01 | 4.71e-02 | 6.92e-02 | 1.27e-01 | 7.36e-01 | 2.31e-02 |
| TRANSLESION SYNTHESIS BY POLH | 19 | 2.58e-02 | 6.10e-02 | 0.5110 | -0.021600 | 0.160000 | 0.102000 | 4.70e-01 | -5.93e-02 | 8.70e-01 | 2.28e-01 | 4.42e-01 | 3.91e-04 | 6.54e-01 |
| GLUTATHIONE CONJUGATION | 29 | 3.00e-03 | 1.09e-02 | 0.5090 | -0.116000 | 0.280000 | -0.032900 | 4.02e-01 | -6.90e-02 | 2.81e-01 | 9.16e-03 | 7.59e-01 | 1.79e-04 | 5.20e-01 |
| ASYMMETRIC LOCALIZATION OF PCP PROTEINS | 62 | 1.27e-08 | 1.70e-07 | 0.5090 | -0.325000 | 0.061600 | 0.012800 | 3.76e-01 | -8.61e-02 | 9.74e-06 | 4.01e-01 | 8.62e-01 | 2.97e-07 | 2.41e-01 |
| BASE EXCISION REPAIR AP SITE FORMATION | 27 | 3.69e-03 | 1.30e-02 | 0.5080 | -0.198000 | 0.118000 | -0.015700 | 3.93e-01 | -2.25e-01 | 7.46e-02 | 2.91e-01 | 8.88e-01 | 4.12e-04 | 4.33e-02 |
| PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES | 13 | 4.21e-02 | 9.02e-02 | 0.5080 | -0.138000 | -0.116000 | -0.236000 | -1.10e-01 | 3.97e-01 | 3.89e-01 | 4.69e-01 | 1.40e-01 | 4.91e-01 | 1.33e-02 |
| SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE | 85 | 6.62e-12 | 1.66e-10 | 0.5060 | -0.293000 | 0.084200 | 0.044500 | 3.94e-01 | -7.32e-02 | 2.93e-06 | 1.80e-01 | 4.79e-01 | 3.42e-10 | 2.44e-01 |
| MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES | 31 | 1.05e-03 | 4.60e-03 | 0.5060 | 0.141000 | -0.238000 | 0.165000 | -3.29e-01 | 2.10e-01 | 1.76e-01 | 2.20e-02 | 1.11e-01 | 1.53e-03 | 4.33e-02 |
| ACTIVATION OF RAC1 | 13 | 7.38e-02 | 1.39e-01 | 0.5060 | -0.170000 | -0.135000 | -0.039000 | -4.55e-01 | -2.51e-03 | 2.90e-01 | 3.98e-01 | 8.08e-01 | 4.49e-03 | 9.88e-01 |
| RNA POLYMERASE II TRANSCRIPTION TERMINATION | 65 | 7.59e-09 | 1.08e-07 | 0.5060 | -0.256000 | -0.088300 | 0.109000 | 1.38e-01 | -3.89e-01 | 3.63e-04 | 2.19e-01 | 1.28e-01 | 5.53e-02 | 5.65e-08 |
| ANCHORING FIBRIL FORMATION | 13 | 1.25e-01 | 2.08e-01 | 0.5050 | 0.219000 | -0.207000 | 0.300000 | -2.40e-01 | 1.31e-01 | 1.72e-01 | 1.97e-01 | 6.15e-02 | 1.34e-01 | 4.14e-01 |
| ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 | 22 | 1.41e-02 | 3.85e-02 | 0.5050 | -0.313000 | -0.258000 | -0.003260 | 6.55e-02 | -2.93e-01 | 1.10e-02 | 3.63e-02 | 9.79e-01 | 5.95e-01 | 1.73e-02 |
| INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | 29 | 1.50e-03 | 6.05e-03 | 0.5050 | -0.369000 | -0.022900 | -0.060500 | 2.97e-01 | -1.62e-01 | 5.90e-04 | 8.31e-01 | 5.73e-01 | 5.61e-03 | 1.32e-01 |
| REGULATION OF TLR BY ENDOGENOUS LIGAND | 10 | 1.61e-01 | 2.50e-01 | 0.5040 | -0.298000 | 0.080600 | -0.088200 | 3.80e-01 | 8.16e-02 | 1.02e-01 | 6.59e-01 | 6.29e-01 | 3.75e-02 | 6.55e-01 |
| PROLONGED ERK ACTIVATION EVENTS | 12 | 1.38e-01 | 2.23e-01 | 0.5000 | 0.076000 | -0.215000 | 0.043100 | -2.62e-01 | 3.58e-01 | 6.48e-01 | 1.98e-01 | 7.96e-01 | 1.16e-01 | 3.19e-02 |
| RHO GTPASES ACTIVATE NADPH OXIDASES | 19 | 7.32e-02 | 1.38e-01 | 0.5000 | 0.218000 | 0.059100 | 0.270000 | 6.67e-02 | 3.49e-01 | 1.00e-01 | 6.56e-01 | 4.18e-02 | 6.15e-01 | 8.47e-03 |
| HIV TRANSCRIPTION ELONGATION | 42 | 4.48e-05 | 2.85e-04 | 0.5000 | -0.109000 | 0.149000 | 0.240000 | 3.48e-01 | -1.92e-01 | 2.22e-01 | 9.54e-02 | 7.08e-03 | 9.54e-05 | 3.16e-02 |
| ERKS ARE INACTIVATED | 13 | 4.14e-02 | 8.96e-02 | 0.4990 | 0.006130 | -0.233000 | 0.286000 | -8.99e-02 | 3.24e-01 | 9.69e-01 | 1.45e-01 | 7.43e-02 | 5.75e-01 | 4.32e-02 |
| SHC MEDIATED CASCADE FGFR3 | 12 | 5.15e-02 | 1.06e-01 | 0.4990 | -0.050500 | -0.043100 | -0.425000 | 6.21e-02 | 2.45e-01 | 7.62e-01 | 7.96e-01 | 1.09e-02 | 7.10e-01 | 1.41e-01 |
| CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING | 28 | 4.19e-03 | 1.42e-02 | 0.4970 | 0.206000 | -0.237000 | 0.176000 | -2.52e-01 | 2.33e-01 | 5.90e-02 | 3.03e-02 | 1.07e-01 | 2.10e-02 | 3.28e-02 |
| REGULATION OF RUNX2 EXPRESSION AND ACTIVITY | 67 | 3.15e-09 | 4.78e-08 | 0.4970 | -0.284000 | -0.073300 | 0.010000 | 3.56e-01 | -1.85e-01 | 5.73e-05 | 3.00e-01 | 8.87e-01 | 4.79e-07 | 8.75e-03 |
| FRS MEDIATED FGFR4 SIGNALING | 12 | 7.40e-02 | 1.39e-01 | 0.4970 | -0.082700 | -0.032200 | -0.450000 | 2.09e-05 | 1.92e-01 | 6.20e-01 | 8.47e-01 | 6.96e-03 | 1.00e+00 | 2.49e-01 |
| NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING | 34 | 3.67e-03 | 1.29e-02 | 0.4970 | -0.365000 | -0.219000 | -0.178000 | -1.26e-01 | -1.35e-01 | 2.32e-04 | 2.70e-02 | 7.26e-02 | 2.03e-01 | 1.74e-01 |
| SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES | 29 | 3.98e-03 | 1.38e-02 | 0.4960 | -0.427000 | -0.036700 | -0.160000 | 1.39e-01 | -1.31e-01 | 6.90e-05 | 7.32e-01 | 1.37e-01 | 1.95e-01 | 2.23e-01 |
| SULFUR AMINO ACID METABOLISM | 23 | 1.72e-03 | 6.90e-03 | 0.4950 | -0.152000 | 0.113000 | -0.099900 | 3.46e-01 | 2.82e-01 | 2.06e-01 | 3.48e-01 | 4.07e-01 | 4.03e-03 | 1.94e-02 |
| P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 12 | 2.09e-01 | 3.02e-01 | 0.4950 | -0.273000 | -0.264000 | -0.168000 | -2.63e-01 | 6.43e-02 | 1.02e-01 | 1.14e-01 | 3.15e-01 | 1.15e-01 | 7.00e-01 |
| REGULATION OF RAS BY GAPS | 66 | 1.38e-09 | 2.18e-08 | 0.4950 | -0.311000 | -0.080300 | 0.003650 | 3.58e-01 | -1.17e-01 | 1.25e-05 | 2.59e-01 | 9.59e-01 | 4.88e-07 | 1.01e-01 |
| G BETA GAMMA SIGNALLING THROUGH CDC42 | 18 | 2.21e-02 | 5.42e-02 | 0.4940 | -0.321000 | -0.149000 | 0.045100 | 2.67e-01 | -2.11e-01 | 1.83e-02 | 2.72e-01 | 7.40e-01 | 4.97e-02 | 1.21e-01 |
| RAS PROCESSING | 23 | 1.09e-03 | 4.71e-03 | 0.4920 | -0.199000 | -0.015800 | -0.021400 | 4.29e-01 | 1.34e-01 | 9.93e-02 | 8.96e-01 | 8.59e-01 | 3.69e-04 | 2.66e-01 |
| BBSOME MEDIATED CARGO TARGETING TO CILIUM | 23 | 3.99e-02 | 8.75e-02 | 0.4920 | -0.353000 | -0.106000 | -0.164000 | 1.12e-01 | -2.58e-01 | 3.39e-03 | 3.79e-01 | 1.72e-01 | 3.52e-01 | 3.21e-02 |
| POST CHAPERONIN TUBULIN FOLDING PATHWAY | 17 | 4.18e-02 | 9.01e-02 | 0.4920 | -0.219000 | 0.131000 | 0.190000 | 3.66e-01 | -8.06e-02 | 1.18e-01 | 3.52e-01 | 1.76e-01 | 8.93e-03 | 5.65e-01 |
| THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION | 13 | 3.80e-02 | 8.43e-02 | 0.4910 | 0.200000 | 0.404000 | -0.145000 | 9.46e-02 | -8.61e-02 | 2.13e-01 | 1.16e-02 | 3.65e-01 | 5.55e-01 | 5.91e-01 |
| SIGNALING BY ERBB2 IN CANCER | 24 | 5.27e-02 | 1.07e-01 | 0.4900 | -0.175000 | -0.214000 | -0.298000 | -2.54e-01 | -1.01e-01 | 1.39e-01 | 6.90e-02 | 1.15e-02 | 3.10e-02 | 3.90e-01 |
| NCAM SIGNALING FOR NEURITE OUT GROWTH | 55 | 1.13e-07 | 1.31e-06 | 0.4890 | 0.049500 | -0.222000 | 0.251000 | -3.53e-01 | 4.64e-03 | 5.26e-01 | 4.45e-03 | 1.29e-03 | 5.99e-06 | 9.53e-01 |
| RUNX2 REGULATES BONE DEVELOPMENT | 28 | 1.05e-02 | 3.06e-02 | 0.4890 | -0.155000 | -0.224000 | -0.128000 | -3.79e-01 | -6.99e-02 | 1.56e-01 | 3.98e-02 | 2.42e-01 | 5.22e-04 | 5.22e-01 |
| NCAM1 INTERACTIONS | 35 | 6.87e-05 | 4.08e-04 | 0.4890 | 0.022700 | -0.220000 | 0.228000 | -3.48e-01 | -1.30e-01 | 8.17e-01 | 2.45e-02 | 1.95e-02 | 3.67e-04 | 1.83e-01 |
| RNA POLYMERASE III TRANSCRIPTION TERMINATION | 23 | 1.15e-02 | 3.24e-02 | 0.4880 | -0.001530 | 0.137000 | 0.086800 | 4.59e-01 | 2.94e-02 | 9.90e-01 | 2.54e-01 | 4.71e-01 | 1.37e-04 | 8.07e-01 |
| GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER | 24 | 1.40e-02 | 3.83e-02 | 0.4870 | -0.262000 | 0.128000 | 0.040800 | 3.29e-01 | -2.05e-01 | 2.62e-02 | 2.79e-01 | 7.30e-01 | 5.25e-03 | 8.20e-02 |
| CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY | 83 | 5.32e-11 | 1.06e-09 | 0.4860 | -0.334000 | 0.061900 | -0.002130 | 3.44e-01 | -4.74e-02 | 1.41e-07 | 3.30e-01 | 9.73e-01 | 6.05e-08 | 4.55e-01 |
| VEGFR2 MEDIATED CELL PROLIFERATION | 19 | 3.05e-02 | 7.02e-02 | 0.4860 | 0.042600 | -0.328000 | -0.116000 | -2.20e-01 | 2.54e-01 | 7.48e-01 | 1.33e-02 | 3.83e-01 | 9.71e-02 | 5.52e-02 |
| ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM | 12 | 9.78e-02 | 1.74e-01 | 0.4850 | -0.026500 | 0.286000 | -0.202000 | 2.65e-02 | 3.33e-01 | 8.74e-01 | 8.61e-02 | 2.26e-01 | 8.74e-01 | 4.59e-02 |
| RECEPTOR MEDIATED MITOPHAGY | 11 | 7.95e-02 | 1.48e-01 | 0.4840 | -0.044500 | -0.081200 | 0.196000 | 3.01e-01 | 3.10e-01 | 7.99e-01 | 6.41e-01 | 2.60e-01 | 8.42e-02 | 7.47e-02 |
| INTERLEUKIN 6 FAMILY SIGNALING | 18 | 1.63e-02 | 4.30e-02 | 0.4830 | 0.370000 | -0.099300 | -0.102000 | -3.40e-02 | 2.74e-01 | 6.52e-03 | 4.66e-01 | 4.56e-01 | 8.03e-01 | 4.40e-02 |
| TIGHT JUNCTION INTERACTIONS | 14 | 5.10e-02 | 1.05e-01 | 0.4820 | -0.236000 | 0.199000 | -0.275000 | 4.75e-02 | 2.44e-01 | 1.27e-01 | 1.98e-01 | 7.46e-02 | 7.59e-01 | 1.13e-01 |
| INTERFERON GAMMA SIGNALING | 75 | 5.45e-07 | 5.55e-06 | 0.4810 | -0.085900 | -0.226000 | -0.318000 | -1.55e-01 | -2.19e-01 | 1.99e-01 | 7.20e-04 | 1.95e-06 | 2.06e-02 | 1.04e-03 |
| POLYMERASE SWITCHING | 14 | 1.35e-01 | 2.20e-01 | 0.4810 | -0.002920 | 0.178000 | 0.050700 | 4.14e-01 | -1.59e-01 | 9.85e-01 | 2.48e-01 | 7.42e-01 | 7.27e-03 | 3.02e-01 |
| ABC TRANSPORTER DISORDERS | 68 | 1.35e-08 | 1.78e-07 | 0.4810 | -0.275000 | 0.013800 | 0.034800 | 3.73e-01 | -1.23e-01 | 8.65e-05 | 8.45e-01 | 6.20e-01 | 1.06e-07 | 7.99e-02 |
| CD209 DC SIGN SIGNALING | 18 | 1.10e-01 | 1.90e-01 | 0.4810 | -0.086000 | -0.327000 | -0.190000 | -2.78e-01 | 5.94e-02 | 5.27e-01 | 1.63e-02 | 1.63e-01 | 4.14e-02 | 6.62e-01 |
| RNA POLYMERASE I TRANSCRIPTION TERMINATION | 31 | 1.78e-03 | 7.09e-03 | 0.4810 | -0.110000 | 0.097200 | 0.174000 | 3.50e-01 | -2.39e-01 | 2.88e-01 | 3.49e-01 | 9.41e-02 | 7.54e-04 | 2.14e-02 |
| SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | 52 | 1.84e-05 | 1.26e-04 | 0.4800 | 0.250000 | -0.162000 | 0.029100 | -2.09e-01 | 3.12e-01 | 1.84e-03 | 4.36e-02 | 7.17e-01 | 9.14e-03 | 9.87e-05 |
| PREGNENOLONE BIOSYNTHESIS | 12 | 1.83e-01 | 2.74e-01 | 0.4800 | -0.321000 | -0.070900 | -0.033900 | 2.94e-01 | -1.87e-01 | 5.45e-02 | 6.71e-01 | 8.39e-01 | 7.76e-02 | 2.63e-01 |
| PROTEIN METHYLATION | 17 | 5.20e-02 | 1.07e-01 | 0.4800 | -0.038600 | 0.166000 | -0.083200 | 3.97e-01 | -1.92e-01 | 7.83e-01 | 2.36e-01 | 5.53e-01 | 4.65e-03 | 1.70e-01 |
| EPHRIN SIGNALING | 19 | 6.49e-02 | 1.27e-01 | 0.4790 | -0.011400 | -0.357000 | 0.014300 | -3.19e-01 | 2.12e-02 | 9.31e-01 | 7.08e-03 | 9.14e-01 | 1.62e-02 | 8.73e-01 |
| REPRESSION OF WNT TARGET GENES | 14 | 2.41e-02 | 5.79e-02 | 0.4780 | -0.158000 | 0.141000 | -0.130000 | -4.08e-01 | -1.26e-02 | 3.07e-01 | 3.61e-01 | 3.98e-01 | 8.17e-03 | 9.35e-01 |
| APC CDC20 MEDIATED DEGRADATION OF NEK2A | 25 | 1.19e-02 | 3.34e-02 | 0.4780 | -0.198000 | 0.182000 | 0.140000 | 3.56e-01 | -9.87e-02 | 8.73e-02 | 1.16e-01 | 2.25e-01 | 2.04e-03 | 3.93e-01 |
| EARLY PHASE OF HIV LIFE CYCLE | 13 | 1.58e-01 | 2.46e-01 | 0.4780 | -0.214000 | 0.226000 | -0.227000 | 9.33e-02 | -2.67e-01 | 1.82e-01 | 1.59e-01 | 1.57e-01 | 5.60e-01 | 9.50e-02 |
| SCAVENGING BY CLASS A RECEPTORS | 13 | 2.32e-02 | 5.67e-02 | 0.4770 | 0.163000 | 0.147000 | -0.257000 | 9.57e-02 | -3.23e-01 | 3.09e-01 | 3.59e-01 | 1.09e-01 | 5.50e-01 | 4.36e-02 |
| MRNA CAPPING | 29 | 3.14e-03 | 1.13e-02 | 0.4770 | -0.189000 | 0.091400 | 0.131000 | 3.82e-01 | -1.44e-01 | 7.79e-02 | 3.95e-01 | 2.21e-01 | 3.77e-04 | 1.80e-01 |
| RHOV GTPASE CYCLE | 32 | 2.78e-03 | 1.03e-02 | 0.4750 | 0.055200 | -0.204000 | -0.009570 | -4.25e-01 | 1.85e-02 | 5.89e-01 | 4.62e-02 | 9.25e-01 | 3.14e-05 | 8.56e-01 |
| ACTIVATION OF GENE EXPRESSION BY SREBF SREBP | 43 | 4.98e-04 | 2.44e-03 | 0.4750 | -0.102000 | -0.312000 | -0.062300 | -3.36e-01 | 2.60e-02 | 2.49e-01 | 3.97e-04 | 4.80e-01 | 1.37e-04 | 7.68e-01 |
| NUCLEOBASE CATABOLISM | 31 | 4.11e-03 | 1.40e-02 | 0.4740 | -0.087700 | 0.338000 | 0.109000 | 2.47e-01 | 1.74e-01 | 3.98e-01 | 1.13e-03 | 2.95e-01 | 1.73e-02 | 9.30e-02 |
| PROTEIN LOCALIZATION | 157 | 2.20e-19 | 1.10e-17 | 0.4740 | -0.138000 | 0.141000 | 0.008730 | 4.29e-01 | 3.84e-02 | 2.92e-03 | 2.25e-03 | 8.50e-01 | 1.69e-20 | 4.07e-01 |
| RA BIOSYNTHESIS PATHWAY | 12 | 1.01e-01 | 1.79e-01 | 0.4730 | -0.047600 | 0.204000 | -0.359000 | 2.23e-01 | 4.32e-02 | 7.75e-01 | 2.21e-01 | 3.15e-02 | 1.81e-01 | 7.96e-01 |
| SIGNALING BY EGFR IN CANCER | 21 | 1.13e-01 | 1.94e-01 | 0.4730 | -0.247000 | -0.171000 | -0.206000 | -2.57e-02 | -3.00e-01 | 5.01e-02 | 1.75e-01 | 1.02e-01 | 8.38e-01 | 1.72e-02 |
| GLYCOGEN STORAGE DISEASES | 12 | 1.22e-01 | 2.05e-01 | 0.4720 | -0.427000 | 0.040900 | -0.141000 | 1.11e-01 | 8.14e-02 | 1.04e-02 | 8.06e-01 | 3.99e-01 | 5.06e-01 | 6.26e-01 |
| MITOCHONDRIAL CALCIUM ION TRANSPORT | 23 | 2.16e-02 | 5.33e-02 | 0.4710 | 0.004510 | 0.192000 | 0.015300 | 4.27e-01 | -4.43e-02 | 9.70e-01 | 1.10e-01 | 8.99e-01 | 3.91e-04 | 7.13e-01 |
| BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION | 25 | 2.34e-02 | 5.69e-02 | 0.4700 | 0.157000 | -0.286000 | -0.037200 | -3.31e-01 | 5.51e-02 | 1.74e-01 | 1.33e-02 | 7.48e-01 | 4.16e-03 | 6.34e-01 |
| PKMTS METHYLATE HISTONE LYSINES | 47 | 2.53e-04 | 1.32e-03 | 0.4690 | 0.077800 | -0.311000 | -0.136000 | -3.01e-01 | -9.16e-02 | 3.57e-01 | 2.28e-04 | 1.06e-01 | 3.54e-04 | 2.77e-01 |
| GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | 14 | 1.40e-01 | 2.25e-01 | 0.4680 | -0.120000 | -0.104000 | -0.353000 | -2.04e-01 | 1.67e-01 | 4.36e-01 | 5.01e-01 | 2.22e-02 | 1.87e-01 | 2.80e-01 |
| HDR THROUGH MMEJ ALT NHEJ | 10 | 1.84e-01 | 2.74e-01 | 0.4680 | 0.371000 | -0.037300 | 0.207000 | -6.75e-03 | -1.91e-01 | 4.19e-02 | 8.38e-01 | 2.56e-01 | 9.71e-01 | 2.96e-01 |
| SIGNALING BY ERYTHROPOIETIN | 24 | 2.41e-02 | 5.79e-02 | 0.4670 | 0.044200 | -0.387000 | -0.055400 | -2.41e-01 | 7.49e-02 | 7.08e-01 | 1.05e-03 | 6.38e-01 | 4.07e-02 | 5.25e-01 |
| RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY | 24 | 2.58e-02 | 6.10e-02 | 0.4670 | -0.091100 | 0.181000 | 0.138000 | 3.96e-01 | -3.06e-02 | 4.40e-01 | 1.25e-01 | 2.41e-01 | 7.79e-04 | 7.96e-01 |
| TRANSCRIPTIONAL REGULATION BY MECP2 | 58 | 3.62e-06 | 3.00e-05 | 0.4670 | 0.221000 | -0.221000 | 0.153000 | -3.10e-01 | -1.04e-02 | 3.61e-03 | 3.56e-03 | 4.35e-02 | 4.36e-05 | 8.91e-01 |
| RHOU GTPASE CYCLE | 33 | 3.71e-03 | 1.30e-02 | 0.4660 | 0.195000 | -0.144000 | 0.011100 | -3.50e-01 | 1.89e-01 | 5.21e-02 | 1.53e-01 | 9.12e-01 | 5.11e-04 | 5.99e-02 |
| PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | 51 | 1.88e-05 | 1.28e-04 | 0.4650 | 0.047200 | 0.189000 | 0.010500 | 3.35e-01 | 2.59e-01 | 5.60e-01 | 1.99e-02 | 8.97e-01 | 3.60e-05 | 1.41e-03 |
| MTORC1 MEDIATED SIGNALLING | 24 | 4.02e-02 | 8.76e-02 | 0.4650 | 0.018400 | 0.213000 | 0.205000 | 2.96e-01 | 2.02e-01 | 8.76e-01 | 7.06e-02 | 8.17e-02 | 1.20e-02 | 8.64e-02 |
| ADHERENS JUNCTIONS INTERACTIONS | 30 | 1.29e-04 | 7.33e-04 | 0.4650 | -0.205000 | -0.035300 | 0.025600 | -4.10e-01 | 6.66e-02 | 5.26e-02 | 7.38e-01 | 8.08e-01 | 1.03e-04 | 5.28e-01 |
| GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | 29 | 1.71e-02 | 4.43e-02 | 0.4650 | 0.159000 | 0.219000 | 0.074800 | 2.17e-01 | 3.00e-01 | 1.38e-01 | 4.17e-02 | 4.86e-01 | 4.30e-02 | 5.17e-03 |
| SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III | 23 | 1.75e-02 | 4.49e-02 | 0.4640 | -0.119000 | 0.112000 | 0.261000 | 3.35e-01 | -9.23e-02 | 3.21e-01 | 3.51e-01 | 3.05e-02 | 5.40e-03 | 4.44e-01 |
| PLASMA LIPOPROTEIN REMODELING | 13 | 2.78e-01 | 3.75e-01 | 0.4640 | 0.290000 | 0.228000 | 0.052800 | 1.58e-01 | 2.26e-01 | 7.00e-02 | 1.54e-01 | 7.42e-01 | 3.23e-01 | 1.58e-01 |
| METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS | 10 | 3.33e-01 | 4.29e-01 | 0.4640 | 0.265000 | 0.356000 | 0.026400 | 5.68e-02 | 1.20e-01 | 1.47e-01 | 5.13e-02 | 8.85e-01 | 7.56e-01 | 5.10e-01 |
| PEROXISOMAL LIPID METABOLISM | 26 | 1.65e-02 | 4.32e-02 | 0.4630 | 0.082300 | 0.263000 | -0.023200 | 3.02e-01 | 2.17e-01 | 4.68e-01 | 2.01e-02 | 8.38e-01 | 7.78e-03 | 5.54e-02 |
| APOPTOTIC FACTOR MEDIATED RESPONSE | 18 | 2.88e-02 | 6.67e-02 | 0.4620 | -0.259000 | -0.068000 | -0.166000 | 3.38e-01 | -5.78e-03 | 5.74e-02 | 6.17e-01 | 2.24e-01 | 1.30e-02 | 9.66e-01 |
| SIGNAL AMPLIFICATION | 29 | 1.29e-02 | 3.58e-02 | 0.4610 | -0.320000 | -0.257000 | -0.066600 | -7.34e-03 | -2.01e-01 | 2.89e-03 | 1.68e-02 | 5.35e-01 | 9.45e-01 | 6.15e-02 |
| MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | 15 | 5.30e-02 | 1.08e-01 | 0.4610 | -0.233000 | -0.046800 | 0.177000 | 3.46e-01 | -7.13e-02 | 1.18e-01 | 7.54e-01 | 2.34e-01 | 2.05e-02 | 6.33e-01 |
| HIV ELONGATION ARREST AND RECOVERY | 32 | 1.95e-03 | 7.73e-03 | 0.4610 | -0.080400 | 0.069200 | 0.193000 | 3.06e-01 | -2.64e-01 | 4.31e-01 | 4.98e-01 | 5.86e-02 | 2.70e-03 | 9.63e-03 |
| ZINC TRANSPORTERS | 14 | 2.57e-01 | 3.54e-01 | 0.4590 | 0.365000 | -0.037200 | 0.165000 | -8.59e-02 | 2.02e-01 | 1.79e-02 | 8.10e-01 | 2.84e-01 | 5.78e-01 | 1.90e-01 |
| PHASE 0 RAPID DEPOLARISATION | 28 | 1.39e-02 | 3.81e-02 | 0.4590 | 0.253000 | -0.046100 | 0.234000 | -2.54e-01 | 1.59e-01 | 2.07e-02 | 6.73e-01 | 3.18e-02 | 2.01e-02 | 1.47e-01 |
| TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 | 12 | 4.21e-01 | 5.17e-01 | 0.4580 | -0.299000 | -0.163000 | -0.226000 | 4.40e-02 | -2.03e-01 | 7.29e-02 | 3.28e-01 | 1.75e-01 | 7.92e-01 | 2.24e-01 |
| MITOPHAGY | 29 | 1.22e-03 | 5.11e-03 | 0.4580 | -0.159000 | -0.011900 | 0.101000 | 4.17e-01 | -1.47e-02 | 1.40e-01 | 9.11e-01 | 3.45e-01 | 1.00e-04 | 8.91e-01 |
| RESOLUTION OF ABASIC SITES AP SITES | 37 | 1.18e-03 | 4.97e-03 | 0.4580 | -0.018100 | 0.110000 | 0.235000 | 3.53e-01 | -1.32e-01 | 8.49e-01 | 2.47e-01 | 1.32e-02 | 2.04e-04 | 1.64e-01 |
| VEGFR2 MEDIATED VASCULAR PERMEABILITY | 26 | 1.90e-02 | 4.82e-02 | 0.4570 | -0.078700 | -0.264000 | -0.172000 | -2.66e-01 | 1.81e-01 | 4.87e-01 | 1.98e-02 | 1.29e-01 | 1.87e-02 | 1.11e-01 |
| PI3K EVENTS IN ERBB2 SIGNALING | 14 | 2.08e-01 | 3.02e-01 | 0.4570 | -0.108000 | -0.084300 | -0.237000 | -3.37e-01 | -1.43e-01 | 4.84e-01 | 5.85e-01 | 1.25e-01 | 2.89e-02 | 3.55e-01 |
| MEIOTIC RECOMBINATION | 35 | 2.66e-03 | 1.00e-02 | 0.4570 | -0.267000 | 0.205000 | -0.218000 | 1.95e-01 | -1.01e-01 | 6.37e-03 | 3.57e-02 | 2.56e-02 | 4.59e-02 | 3.01e-01 |
| PRC2 METHYLATES HISTONES AND DNA | 26 | 2.56e-02 | 6.08e-02 | 0.4570 | -0.225000 | 0.042500 | -0.211000 | 2.35e-01 | -2.37e-01 | 4.70e-02 | 7.08e-01 | 6.32e-02 | 3.78e-02 | 3.62e-02 |
| INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE | 22 | 2.67e-02 | 6.29e-02 | 0.4570 | -0.046200 | 0.085400 | 0.207000 | 3.93e-01 | 4.29e-02 | 7.08e-01 | 4.88e-01 | 9.28e-02 | 1.43e-03 | 7.28e-01 |
| CELLULAR RESPONSE TO CHEMICAL STRESS | 149 | 3.04e-16 | 1.30e-14 | 0.4560 | -0.203000 | 0.058800 | -0.006210 | 3.74e-01 | -1.53e-01 | 1.84e-05 | 2.16e-01 | 8.96e-01 | 3.36e-15 | 1.33e-03 |
| INTERLEUKIN 12 SIGNALING | 36 | 1.30e-03 | 5.40e-03 | 0.4540 | -0.275000 | 0.060700 | -0.073500 | 3.38e-01 | -8.47e-02 | 4.24e-03 | 5.29e-01 | 4.45e-01 | 4.52e-04 | 3.79e-01 |
| ACTIVATION OF SMO | 16 | 9.98e-02 | 1.77e-01 | 0.4540 | -0.062200 | -0.253000 | -0.010400 | -2.99e-01 | 2.20e-01 | 6.67e-01 | 7.94e-02 | 9.42e-01 | 3.87e-02 | 1.27e-01 |
| IRAK4 DEFICIENCY TLR2 4 | 11 | 1.66e-01 | 2.56e-01 | 0.4540 | -0.271000 | 0.034800 | -0.236000 | 1.69e-01 | 2.17e-01 | 1.20e-01 | 8.42e-01 | 1.76e-01 | 3.33e-01 | 2.12e-01 |
| SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL | 10 | 1.51e-01 | 2.39e-01 | 0.4530 | -0.182000 | 0.175000 | 0.240000 | 6.48e-02 | 2.84e-01 | 3.20e-01 | 3.38e-01 | 1.90e-01 | 7.23e-01 | 1.20e-01 |
| DNA REPLICATION | 119 | 4.43e-13 | 1.31e-11 | 0.4530 | -0.222000 | 0.091800 | 0.029800 | 3.78e-01 | -5.87e-02 | 2.98e-05 | 8.41e-02 | 5.75e-01 | 1.02e-12 | 2.69e-01 |
| REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM | 10 | 1.31e-01 | 2.14e-01 | 0.4530 | -0.126000 | -0.081900 | 0.214000 | -2.62e-01 | 2.61e-01 | 4.90e-01 | 6.54e-01 | 2.42e-01 | 1.52e-01 | 1.53e-01 |
| APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B | 21 | 5.28e-02 | 1.07e-01 | 0.4520 | -0.234000 | 0.160000 | 0.059900 | 3.27e-01 | -1.17e-01 | 6.38e-02 | 2.04e-01 | 6.35e-01 | 9.43e-03 | 3.54e-01 |
| DNA DAMAGE RECOGNITION IN GG NER | 38 | 3.77e-03 | 1.31e-02 | 0.4520 | 0.034000 | 0.188000 | 0.180000 | 3.68e-01 | 8.73e-03 | 7.17e-01 | 4.53e-02 | 5.51e-02 | 8.55e-05 | 9.26e-01 |
| ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING | 20 | 9.34e-02 | 1.68e-01 | 0.4520 | -0.110000 | -0.261000 | -0.046900 | -3.45e-01 | -4.42e-02 | 3.92e-01 | 4.31e-02 | 7.17e-01 | 7.48e-03 | 7.32e-01 |
| TNFR2 NON CANONICAL NF KB PATHWAY | 76 | 2.14e-08 | 2.81e-07 | 0.4520 | -0.276000 | -0.007350 | -0.028900 | 3.40e-01 | -1.07e-01 | 3.14e-05 | 9.12e-01 | 6.63e-01 | 3.09e-07 | 1.08e-01 |
| CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX | 10 | 1.87e-01 | 2.77e-01 | 0.4510 | -0.420000 | 0.034200 | 0.015200 | 1.52e-01 | 4.94e-02 | 2.14e-02 | 8.52e-01 | 9.34e-01 | 4.06e-01 | 7.87e-01 |
| CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | 12 | 3.12e-01 | 4.08e-01 | 0.4500 | 0.029800 | 0.198000 | 0.227000 | 1.40e-01 | 3.02e-01 | 8.58e-01 | 2.35e-01 | 1.74e-01 | 4.01e-01 | 7.00e-02 |
| METABOLISM OF COFACTORS | 18 | 8.40e-02 | 1.55e-01 | 0.4480 | -0.182000 | 0.084000 | -0.088600 | 3.75e-01 | -1.08e-01 | 1.81e-01 | 5.37e-01 | 5.15e-01 | 5.89e-03 | 4.27e-01 |
| GAP JUNCTION ASSEMBLY | 20 | 9.31e-02 | 1.68e-01 | 0.4470 | -0.120000 | 0.312000 | 0.019500 | 2.96e-01 | -9.85e-03 | 3.51e-01 | 1.56e-02 | 8.80e-01 | 2.20e-02 | 9.39e-01 |
| FGFR2 MUTANT RECEPTOR ACTIVATION | 24 | 1.60e-02 | 4.24e-02 | 0.4460 | -0.088900 | 0.022700 | 0.038600 | 3.88e-01 | -1.96e-01 | 4.51e-01 | 8.47e-01 | 7.44e-01 | 9.92e-04 | 9.61e-02 |
| REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | 84 | 3.47e-09 | 5.19e-08 | 0.4460 | -0.296000 | -0.052400 | 0.026900 | 2.85e-01 | -1.63e-01 | 2.73e-06 | 4.06e-01 | 6.70e-01 | 6.22e-06 | 9.93e-03 |
| RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER | 28 | 3.51e-02 | 7.85e-02 | 0.4450 | 0.088500 | 0.226000 | 0.125000 | 3.49e-01 | 3.41e-02 | 4.18e-01 | 3.86e-02 | 2.52e-01 | 1.37e-03 | 7.55e-01 |
| FORMATION OF TC NER PRE INCISION COMPLEX | 53 | 4.39e-05 | 2.81e-04 | 0.4430 | -0.127000 | 0.135000 | 0.154000 | 3.72e-01 | -2.92e-03 | 1.09e-01 | 9.04e-02 | 5.32e-02 | 2.76e-06 | 9.71e-01 |
| PLATELET SENSITIZATION BY LDL | 15 | 2.12e-01 | 3.05e-01 | 0.4430 | -0.142000 | -0.178000 | -0.196000 | -3.05e-01 | 1.14e-01 | 3.41e-01 | 2.32e-01 | 1.89e-01 | 4.05e-02 | 4.46e-01 |
| NUCLEOTIDE SALVAGE | 21 | 4.18e-02 | 9.01e-02 | 0.4430 | -0.174000 | 0.194000 | 0.169000 | 3.05e-01 | 8.25e-02 | 1.69e-01 | 1.24e-01 | 1.80e-01 | 1.54e-02 | 5.13e-01 |
| KERATAN SULFATE DEGRADATION | 11 | 5.26e-01 | 6.09e-01 | 0.4420 | 0.237000 | 0.274000 | 0.144000 | 1.40e-01 | 1.55e-01 | 1.74e-01 | 1.16e-01 | 4.10e-01 | 4.21e-01 | 3.73e-01 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 | 17 | 1.12e-01 | 1.93e-01 | 0.4410 | -0.076600 | -0.135000 | -0.385000 | -1.31e-01 | 7.14e-02 | 5.85e-01 | 3.34e-01 | 5.97e-03 | 3.49e-01 | 6.10e-01 |
| PI 3K CASCADE FGFR3 | 12 | 1.29e-01 | 2.12e-01 | 0.4410 | 0.106000 | -0.026400 | -0.382000 | -9.66e-02 | 1.64e-01 | 5.27e-01 | 8.74e-01 | 2.20e-02 | 5.62e-01 | 3.24e-01 |
| HDMS DEMETHYLATE HISTONES | 26 | 2.70e-02 | 6.35e-02 | 0.4400 | 0.188000 | -0.129000 | -0.030300 | -2.41e-01 | 2.88e-01 | 9.76e-02 | 2.56e-01 | 7.89e-01 | 3.38e-02 | 1.10e-02 |
| DAP12 INTERACTIONS | 28 | 1.87e-02 | 4.77e-02 | 0.4400 | -0.301000 | -0.243000 | -0.183000 | 6.83e-02 | -7.84e-02 | 5.89e-03 | 2.63e-02 | 9.41e-02 | 5.31e-01 | 4.73e-01 |
| BASE EXCISION REPAIR | 54 | 6.54e-05 | 3.91e-04 | 0.4390 | -0.119000 | 0.116000 | 0.066800 | 3.73e-01 | -1.47e-01 | 1.31e-01 | 1.40e-01 | 3.96e-01 | 2.10e-06 | 6.16e-02 |
| RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 59 | 1.64e-05 | 1.14e-04 | 0.4380 | -0.211000 | 0.040400 | 0.066300 | 2.94e-01 | -2.35e-01 | 5.05e-03 | 5.91e-01 | 3.78e-01 | 9.68e-05 | 1.81e-03 |
| JOSEPHIN DOMAIN DUBS | 11 | 2.74e-01 | 3.72e-01 | 0.4370 | -0.207000 | -0.020800 | 0.156000 | 2.93e-01 | -1.94e-01 | 2.35e-01 | 9.05e-01 | 3.71e-01 | 9.25e-02 | 2.66e-01 |
| GLUTAMATE AND GLUTAMINE METABOLISM | 13 | 9.16e-02 | 1.66e-01 | 0.4360 | -0.049000 | -0.002500 | -0.081800 | 2.14e-01 | 3.67e-01 | 7.60e-01 | 9.88e-01 | 6.10e-01 | 1.81e-01 | 2.19e-02 |
| VITAMIN B5 PANTOTHENATE METABOLISM | 14 | 1.26e-01 | 2.09e-01 | 0.4360 | 0.057900 | 0.134000 | -0.173000 | -2.31e-02 | 3.72e-01 | 7.08e-01 | 3.87e-01 | 2.63e-01 | 8.81e-01 | 1.60e-02 |
| RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY | 14 | 2.43e-01 | 3.41e-01 | 0.4350 | -0.248000 | -0.105000 | -0.194000 | 2.24e-01 | -1.69e-01 | 1.08e-01 | 4.98e-01 | 2.10e-01 | 1.46e-01 | 2.73e-01 |
| ER QUALITY CONTROL COMPARTMENT ERQC | 21 | 8.92e-02 | 1.62e-01 | 0.4340 | -0.342000 | -0.188000 | -0.163000 | -9.74e-02 | -2.56e-02 | 6.73e-03 | 1.37e-01 | 1.95e-01 | 4.40e-01 | 8.39e-01 |
| PLATELET CALCIUM HOMEOSTASIS | 25 | 6.53e-02 | 1.27e-01 | 0.4340 | 0.265000 | -0.005000 | 0.106000 | -1.49e-01 | 2.91e-01 | 2.20e-02 | 9.66e-01 | 3.57e-01 | 1.97e-01 | 1.18e-02 |
| INSULIN PROCESSING | 24 | 3.27e-02 | 7.42e-02 | 0.4330 | 0.080000 | -0.335000 | 0.072900 | -2.12e-01 | 1.37e-01 | 4.98e-01 | 4.49e-03 | 5.37e-01 | 7.24e-02 | 2.46e-01 |
| INTERLEUKIN 7 SIGNALING | 18 | 8.73e-02 | 1.59e-01 | 0.4330 | 0.306000 | 0.090300 | 0.115000 | -2.55e-01 | 8.74e-02 | 2.48e-02 | 5.07e-01 | 3.97e-01 | 6.10e-02 | 5.21e-01 |
| SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS | 18 | 1.73e-01 | 2.63e-01 | 0.4330 | -0.015400 | -0.213000 | -0.082100 | -3.63e-01 | -5.31e-02 | 9.10e-01 | 1.18e-01 | 5.47e-01 | 7.60e-03 | 6.97e-01 |
| PI METABOLISM | 79 | 1.05e-06 | 9.81e-06 | 0.4320 | 0.192000 | -0.158000 | 0.076300 | -2.08e-01 | 2.76e-01 | 3.25e-03 | 1.51e-02 | 2.41e-01 | 1.42e-03 | 2.32e-05 |
| SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX | 13 | 2.45e-01 | 3.42e-01 | 0.4320 | -0.092300 | 0.175000 | -0.109000 | 3.67e-01 | 1.05e-02 | 5.64e-01 | 2.74e-01 | 4.95e-01 | 2.18e-02 | 9.48e-01 |
| DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | 78 | 1.04e-08 | 1.41e-07 | 0.4310 | -0.244000 | -0.053700 | 0.014500 | 3.41e-01 | -8.49e-02 | 1.93e-04 | 4.13e-01 | 8.25e-01 | 2.00e-07 | 1.95e-01 |
| HIV TRANSCRIPTION INITIATION | 45 | 5.39e-04 | 2.61e-03 | 0.4310 | -0.210000 | 0.040700 | 0.029000 | 3.19e-01 | -1.93e-01 | 1.48e-02 | 6.36e-01 | 7.37e-01 | 2.11e-04 | 2.50e-02 |
| NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 1.06e-01 | 1.85e-01 | 0.4310 | 0.246000 | -0.185000 | 0.274000 | -1.14e-01 | -4.92e-02 | 7.91e-02 | 1.86e-01 | 5.05e-02 | 4.16e-01 | 7.25e-01 |
| UCH PROTEINASES | 89 | 2.76e-08 | 3.46e-07 | 0.4300 | -0.230000 | 0.054500 | -0.016200 | 3.37e-01 | -1.24e-01 | 1.73e-04 | 3.74e-01 | 7.92e-01 | 4.12e-08 | 4.26e-02 |
| HEME BIOSYNTHESIS | 13 | 2.14e-01 | 3.08e-01 | 0.4300 | 0.109000 | -0.022200 | 0.187000 | 2.24e-01 | 2.96e-01 | 4.95e-01 | 8.90e-01 | 2.43e-01 | 1.62e-01 | 6.51e-02 |
| ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS | 35 | 3.10e-03 | 1.12e-02 | 0.4300 | 0.169000 | -0.172000 | 0.317000 | -1.15e-01 | 1.13e-01 | 8.32e-02 | 7.80e-02 | 1.19e-03 | 2.40e-01 | 2.49e-01 |
| NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | 10 | 4.35e-01 | 5.27e-01 | 0.4270 | -0.224000 | -0.295000 | -0.171000 | 7.47e-02 | -1.02e-01 | 2.21e-01 | 1.06e-01 | 3.49e-01 | 6.83e-01 | 5.75e-01 |
| BUDDING AND MATURATION OF HIV VIRION | 27 | 1.40e-02 | 3.83e-02 | 0.4260 | -0.179000 | 0.076300 | 0.180000 | 3.24e-01 | -7.84e-02 | 1.07e-01 | 4.93e-01 | 1.05e-01 | 3.54e-03 | 4.81e-01 |
| RAF INDEPENDENT MAPK1 3 ACTIVATION | 20 | 6.53e-02 | 1.27e-01 | 0.4260 | 0.101000 | -0.305000 | 0.057200 | -1.64e-01 | 2.19e-01 | 4.36e-01 | 1.82e-02 | 6.58e-01 | 2.04e-01 | 8.96e-02 |
| REGULATION OF BACH1 ACTIVITY | 11 | 4.39e-01 | 5.29e-01 | 0.4250 | -0.021500 | 0.304000 | 0.001780 | 2.77e-01 | -1.03e-01 | 9.02e-01 | 8.10e-02 | 9.92e-01 | 1.11e-01 | 5.54e-01 |
| DEFECTS IN COBALAMIN B12 METABOLISM | 12 | 1.03e-01 | 1.80e-01 | 0.4240 | 0.025800 | -0.017300 | -0.368000 | 2.05e-01 | 3.69e-02 | 8.77e-01 | 9.17e-01 | 2.72e-02 | 2.19e-01 | 8.25e-01 |
| SIGNALING BY PDGFR IN DISEASE | 20 | 1.43e-01 | 2.29e-01 | 0.4240 | 0.014400 | -0.245000 | -0.196000 | -2.68e-01 | 9.58e-02 | 9.11e-01 | 5.81e-02 | 1.29e-01 | 3.79e-02 | 4.58e-01 |
| RHO GTPASES ACTIVATE KTN1 | 11 | 2.88e-01 | 3.83e-01 | 0.4230 | -0.140000 | 0.153000 | -0.258000 | 2.37e-01 | 1.14e-01 | 4.21e-01 | 3.81e-01 | 1.39e-01 | 1.73e-01 | 5.14e-01 |
| SYNTHESIS OF PE | 13 | 1.02e-01 | 1.80e-01 | 0.4220 | 0.083900 | -0.187000 | -0.328000 | 8.90e-03 | 1.69e-01 | 6.01e-01 | 2.43e-01 | 4.05e-02 | 9.56e-01 | 2.93e-01 |
| CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY | 13 | 7.05e-02 | 1.34e-01 | 0.4220 | 0.013200 | -0.302000 | 0.203000 | 1.92e-01 | 9.08e-02 | 9.34e-01 | 5.94e-02 | 2.04e-01 | 2.30e-01 | 5.71e-01 |
| MRNA SPLICING | 188 | 1.28e-17 | 5.91e-16 | 0.4220 | -0.193000 | 0.012300 | 0.064100 | 1.61e-01 | -3.32e-01 | 5.22e-06 | 7.72e-01 | 1.30e-01 | 1.43e-04 | 4.21e-15 |
| FRS MEDIATED FGFR3 SIGNALING | 14 | 8.41e-02 | 1.55e-01 | 0.4210 | 0.043900 | 0.016300 | -0.355000 | 5.33e-02 | 2.15e-01 | 7.76e-01 | 9.16e-01 | 2.14e-02 | 7.30e-01 | 1.63e-01 |
| N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | 35 | 1.17e-02 | 3.30e-02 | 0.4210 | -0.313000 | -0.219000 | -0.128000 | -1.14e-01 | -4.64e-02 | 1.36e-03 | 2.48e-02 | 1.91e-01 | 2.44e-01 | 6.34e-01 |
| GAB1 SIGNALOSOME | 13 | 4.31e-01 | 5.24e-01 | 0.4210 | -0.090300 | -0.161000 | -0.194000 | -2.67e-01 | -1.85e-01 | 5.73e-01 | 3.14e-01 | 2.26e-01 | 9.52e-02 | 2.48e-01 |
| DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA | 63 | 8.25e-04 | 3.74e-03 | 0.4200 | -0.224000 | -0.214000 | -0.238000 | -1.36e-01 | -7.13e-02 | 2.07e-03 | 3.37e-03 | 1.10e-03 | 6.23e-02 | 3.28e-01 |
| INSULIN RECEPTOR RECYCLING | 20 | 1.64e-02 | 4.32e-02 | 0.4200 | -0.045200 | -0.097500 | 0.190000 | 2.93e-01 | 2.06e-01 | 7.27e-01 | 4.50e-01 | 1.42e-01 | 2.32e-02 | 1.11e-01 |
| ION HOMEOSTASIS | 47 | 2.96e-03 | 1.08e-02 | 0.4190 | 0.315000 | -0.035800 | 0.154000 | -4.41e-02 | 2.23e-01 | 1.91e-04 | 6.72e-01 | 6.77e-02 | 6.01e-01 | 8.20e-03 |
| SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | 12 | 4.40e-01 | 5.29e-01 | 0.4180 | -0.255000 | -0.046300 | -0.256000 | 1.53e-01 | -1.38e-01 | 1.26e-01 | 7.81e-01 | 1.25e-01 | 3.60e-01 | 4.10e-01 |
| CYTOPROTECTION BY HMOX1 | 119 | 2.14e-11 | 4.57e-10 | 0.4180 | -0.170000 | 0.014400 | 0.021800 | 3.54e-01 | -1.41e-01 | 1.34e-03 | 7.86e-01 | 6.81e-01 | 2.65e-11 | 7.79e-03 |
| METABOLISM OF RNA | 643 | 1.95e-60 | 3.22e-58 | 0.4170 | -0.186000 | 0.005320 | 0.048500 | 2.77e-01 | -2.45e-01 | 9.61e-16 | 8.19e-01 | 3.71e-02 | 6.75e-33 | 3.98e-26 |
| ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS | 83 | 2.01e-07 | 2.25e-06 | 0.4160 | 0.127000 | -0.217000 | 0.205000 | -1.76e-01 | 1.93e-01 | 4.63e-02 | 6.39e-04 | 1.23e-03 | 5.65e-03 | 2.40e-03 |
| SIGNALING BY LEPTIN | 10 | 4.49e-01 | 5.39e-01 | 0.4160 | 0.336000 | 0.046700 | -0.027300 | -8.41e-02 | 2.24e-01 | 6.62e-02 | 7.98e-01 | 8.81e-01 | 6.45e-01 | 2.19e-01 |
| PLATELET ADHESION TO EXPOSED COLLAGEN | 11 | 2.15e-01 | 3.09e-01 | 0.4160 | -0.003890 | 0.333000 | -0.245000 | -3.33e-03 | 4.26e-02 | 9.82e-01 | 5.56e-02 | 1.60e-01 | 9.85e-01 | 8.07e-01 |
| SIGNALING BY NOTCH4 | 83 | 3.27e-07 | 3.43e-06 | 0.4160 | -0.241000 | 0.065200 | 0.010600 | 3.15e-01 | -1.07e-01 | 1.52e-04 | 3.05e-01 | 8.68e-01 | 7.21e-07 | 9.26e-02 |
| CHONDROITIN SULFATE BIOSYNTHESIS | 18 | 2.52e-01 | 3.51e-01 | 0.4150 | 0.298000 | 0.161000 | 0.159000 | -6.47e-02 | 1.66e-01 | 2.85e-02 | 2.38e-01 | 2.43e-01 | 6.35e-01 | 2.22e-01 |
| OVARIAN TUMOR DOMAIN PROTEASES | 36 | 3.09e-02 | 7.07e-02 | 0.4120 | -0.126000 | -0.268000 | -0.242000 | -1.42e-01 | -6.06e-02 | 1.92e-01 | 5.38e-03 | 1.21e-02 | 1.40e-01 | 5.29e-01 |
| TRAF6 MEDIATED NF KB ACTIVATION | 21 | 1.04e-01 | 1.82e-01 | 0.4120 | -0.060500 | -0.191000 | -0.302000 | -1.64e-01 | 1.09e-01 | 6.31e-01 | 1.30e-01 | 1.67e-02 | 1.93e-01 | 3.88e-01 |
| FCERI MEDIATED MAPK ACTIVATION | 28 | 4.01e-02 | 8.76e-02 | 0.4120 | -0.147000 | -0.299000 | -0.087700 | -2.16e-01 | 6.80e-02 | 1.79e-01 | 6.25e-03 | 4.22e-01 | 4.82e-02 | 5.33e-01 |
| DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | 34 | 9.98e-03 | 2.95e-02 | 0.4120 | -0.164000 | 0.113000 | -0.211000 | 2.64e-01 | -1.23e-01 | 9.77e-02 | 2.52e-01 | 3.37e-02 | 7.62e-03 | 2.13e-01 |
| RHOF GTPASE CYCLE | 39 | 1.21e-03 | 5.08e-03 | 0.4110 | 0.067200 | -0.005040 | -0.117000 | -3.72e-01 | 1.14e-01 | 4.68e-01 | 9.57e-01 | 2.06e-01 | 5.95e-05 | 2.17e-01 |
| RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | 28 | 9.60e-03 | 2.85e-02 | 0.4110 | 0.003420 | 0.008230 | 0.150000 | 3.66e-01 | 1.12e-01 | 9.75e-01 | 9.40e-01 | 1.70e-01 | 7.98e-04 | 3.03e-01 |
| DUAL INCISION IN GG NER | 40 | 5.97e-03 | 1.91e-02 | 0.4110 | -0.066700 | 0.162000 | 0.174000 | 3.20e-01 | -7.55e-02 | 4.66e-01 | 7.57e-02 | 5.71e-02 | 4.63e-04 | 4.09e-01 |
| P75NTR RECRUITS SIGNALLING COMPLEXES | 12 | 3.96e-01 | 4.94e-01 | 0.4110 | -0.132000 | 0.019200 | -0.117000 | 1.62e-01 | -3.33e-01 | 4.28e-01 | 9.08e-01 | 4.84e-01 | 3.30e-01 | 4.60e-02 |
| FORMATION OF THE CORNIFIED ENVELOPE | 20 | 1.85e-01 | 2.74e-01 | 0.4100 | 0.164000 | 0.187000 | 0.319000 | 4.58e-02 | 5.31e-02 | 2.05e-01 | 1.47e-01 | 1.36e-02 | 7.23e-01 | 6.81e-01 |
| KERATINIZATION | 20 | 1.85e-01 | 2.74e-01 | 0.4100 | 0.164000 | 0.187000 | 0.319000 | 4.58e-02 | 5.31e-02 | 2.05e-01 | 1.47e-01 | 1.36e-02 | 7.23e-01 | 6.81e-01 |
| TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | 77 | 8.32e-06 | 6.30e-05 | 0.4100 | 0.182000 | -0.079800 | 0.037100 | -2.29e-01 | 2.73e-01 | 5.67e-03 | 2.27e-01 | 5.74e-01 | 5.26e-04 | 3.44e-05 |
| CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER | 26 | 4.21e-02 | 9.02e-02 | 0.4100 | 0.250000 | -0.198000 | 0.052100 | -1.24e-01 | 2.19e-01 | 2.72e-02 | 8.09e-02 | 6.46e-01 | 2.76e-01 | 5.28e-02 |
| STRIATED MUSCLE CONTRACTION | 21 | 2.46e-02 | 5.88e-02 | 0.4090 | 0.153000 | -0.055000 | 0.143000 | 1.47e-01 | -3.15e-01 | 2.25e-01 | 6.63e-01 | 2.57e-01 | 2.42e-01 | 1.25e-02 |
| REGULATION OF SIGNALING BY CBL | 22 | 7.26e-02 | 1.37e-01 | 0.4090 | -0.085800 | -0.317000 | -0.047100 | -1.95e-01 | 1.37e-01 | 4.86e-01 | 9.98e-03 | 7.02e-01 | 1.13e-01 | 2.67e-01 |
| IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS | 12 | 2.81e-01 | 3.76e-01 | 0.4090 | 0.223000 | -0.066600 | -0.095500 | -2.86e-02 | 3.21e-01 | 1.82e-01 | 6.90e-01 | 5.67e-01 | 8.64e-01 | 5.41e-02 |
| PERK REGULATES GENE EXPRESSION | 28 | 9.46e-03 | 2.81e-02 | 0.4090 | -0.280000 | -0.224000 | -0.038800 | 1.74e-01 | -7.92e-02 | 1.02e-02 | 3.98e-02 | 7.22e-01 | 1.11e-01 | 4.68e-01 |
| CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT | 20 | 6.52e-02 | 1.27e-01 | 0.4090 | -0.087900 | 0.184000 | -0.018200 | 1.77e-01 | 3.07e-01 | 4.96e-01 | 1.55e-01 | 8.88e-01 | 1.72e-01 | 1.76e-02 |
| ELASTIC FIBRE FORMATION | 36 | 1.38e-03 | 5.66e-03 | 0.4080 | 0.318000 | 0.244000 | -0.007560 | -5.35e-02 | 5.32e-02 | 9.59e-04 | 1.14e-02 | 9.37e-01 | 5.78e-01 | 5.81e-01 |
| INTERLEUKIN 10 SIGNALING | 17 | 2.44e-01 | 3.42e-01 | 0.4080 | -0.040900 | -0.204000 | -0.300000 | -1.79e-01 | 2.71e-02 | 7.70e-01 | 1.45e-01 | 3.25e-02 | 2.01e-01 | 8.47e-01 |
| DUAL INCISION IN TC NER | 64 | 3.48e-05 | 2.25e-04 | 0.4060 | -0.152000 | 0.120000 | 0.139000 | 3.23e-01 | -5.85e-02 | 3.53e-02 | 9.69e-02 | 5.41e-02 | 7.82e-06 | 4.19e-01 |
| DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE | 26 | 1.07e-02 | 3.10e-02 | 0.4060 | -0.050200 | -0.044600 | 0.071900 | -2.91e-01 | 2.65e-01 | 6.58e-01 | 6.94e-01 | 5.26e-01 | 1.01e-02 | 1.94e-02 |
| FCERI MEDIATED NF KB ACTIVATION | 76 | 7.60e-07 | 7.55e-06 | 0.4050 | -0.201000 | -0.008270 | -0.020200 | 3.36e-01 | -1.01e-01 | 2.44e-03 | 9.01e-01 | 7.60e-01 | 4.05e-07 | 1.27e-01 |
| SHC1 EVENTS IN EGFR SIGNALING | 10 | 6.39e-01 | 7.00e-01 | 0.4040 | -0.237000 | -0.123000 | -0.291000 | 2.97e-03 | -8.79e-02 | 1.95e-01 | 4.99e-01 | 1.11e-01 | 9.87e-01 | 6.30e-01 |
| KSRP KHSRP BINDS AND DESTABILIZES MRNA | 16 | 9.37e-02 | 1.68e-01 | 0.4040 | -0.081500 | -0.051500 | 0.313000 | 2.35e-01 | 2.81e-02 | 5.73e-01 | 7.21e-01 | 3.04e-02 | 1.03e-01 | 8.46e-01 |
| NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 23 | 9.28e-02 | 1.68e-01 | 0.4040 | -0.055200 | -0.141000 | -0.081500 | -3.33e-01 | -1.50e-01 | 6.47e-01 | 2.42e-01 | 4.99e-01 | 5.69e-03 | 2.14e-01 |
| INTERLEUKIN 20 FAMILY SIGNALING | 12 | 4.50e-01 | 5.39e-01 | 0.4030 | 0.198000 | -0.203000 | 0.071400 | -2.64e-01 | 8.87e-02 | 2.36e-01 | 2.24e-01 | 6.68e-01 | 1.14e-01 | 5.95e-01 |
| REGULATION OF IFNA SIGNALING | 12 | 3.76e-01 | 4.73e-01 | 0.4030 | 0.066500 | -0.328000 | -0.092800 | -1.25e-01 | -1.62e-01 | 6.90e-01 | 4.91e-02 | 5.78e-01 | 4.54e-01 | 3.30e-01 |
| PYRIMIDINE CATABOLISM | 10 | 5.57e-01 | 6.36e-01 | 0.4030 | -0.096900 | 0.304000 | 0.099600 | 2.23e-01 | 3.42e-02 | 5.96e-01 | 9.62e-02 | 5.85e-01 | 2.23e-01 | 8.51e-01 |
| SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL | 25 | 7.05e-02 | 1.34e-01 | 0.4020 | 0.191000 | 0.066000 | 0.004800 | -1.55e-01 | 3.11e-01 | 9.87e-02 | 5.68e-01 | 9.67e-01 | 1.81e-01 | 7.05e-03 |
| NICOTINAMIDE SALVAGING | 15 | 1.73e-01 | 2.63e-01 | 0.4020 | -0.231000 | 0.110000 | 0.073600 | 2.21e-02 | -3.00e-01 | 1.22e-01 | 4.61e-01 | 6.22e-01 | 8.82e-01 | 4.41e-02 |
| GENERATION OF SECOND MESSENGER MOLECULES | 17 | 5.08e-02 | 1.05e-01 | 0.4000 | 0.015800 | 0.220000 | -0.158000 | -5.26e-02 | -2.90e-01 | 9.10e-01 | 1.17e-01 | 2.58e-01 | 7.07e-01 | 3.87e-02 |
| SIGNALING BY RETINOIC ACID | 31 | 1.20e-02 | 3.35e-02 | 0.3990 | 0.087500 | 0.223000 | -0.123000 | 2.31e-01 | 1.83e-01 | 3.99e-01 | 3.14e-02 | 2.36e-01 | 2.59e-02 | 7.83e-02 |
| NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 11 | 2.71e-01 | 3.69e-01 | 0.3990 | 0.139000 | 0.186000 | -0.066900 | -2.83e-01 | 1.44e-01 | 4.26e-01 | 2.86e-01 | 7.01e-01 | 1.04e-01 | 4.08e-01 |
| ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING | 10 | 4.79e-01 | 5.66e-01 | 0.3990 | 0.298000 | 0.021000 | 0.248000 | -4.03e-02 | -7.97e-02 | 1.02e-01 | 9.08e-01 | 1.75e-01 | 8.25e-01 | 6.63e-01 |
| RND3 GTPASE CYCLE | 37 | 5.26e-03 | 1.73e-02 | 0.3990 | -0.082500 | -0.095900 | -0.065700 | -3.64e-01 | -7.67e-02 | 3.85e-01 | 3.13e-01 | 4.89e-01 | 1.26e-04 | 4.19e-01 |
| CD28 DEPENDENT PI3K AKT SIGNALING | 20 | 1.36e-01 | 2.21e-01 | 0.3990 | 0.177000 | -0.131000 | 0.070500 | -9.05e-02 | 3.12e-01 | 1.71e-01 | 3.10e-01 | 5.85e-01 | 4.84e-01 | 1.58e-02 |
| ONCOGENIC MAPK SIGNALING | 76 | 8.76e-06 | 6.55e-05 | 0.3990 | 0.041600 | -0.290000 | 0.049200 | -2.36e-01 | 1.22e-01 | 5.31e-01 | 1.25e-05 | 4.59e-01 | 3.69e-04 | 6.69e-02 |
| RHOBTB1 GTPASE CYCLE | 23 | 2.44e-01 | 3.42e-01 | 0.3990 | -0.208000 | -0.214000 | -0.203000 | -1.35e-01 | -1.02e-01 | 8.42e-02 | 7.59e-02 | 9.23e-02 | 2.61e-01 | 3.97e-01 |
| AMYLOID FIBER FORMATION | 54 | 5.16e-04 | 2.51e-03 | 0.3980 | -0.202000 | 0.031700 | -0.189000 | 2.57e-01 | -1.22e-01 | 1.04e-02 | 6.87e-01 | 1.63e-02 | 1.09e-03 | 1.20e-01 |
| STIMULI SENSING CHANNELS | 73 | 5.17e-05 | 3.17e-04 | 0.3970 | 0.313000 | 0.002700 | 0.053500 | -9.12e-02 | 2.21e-01 | 3.91e-06 | 9.68e-01 | 4.29e-01 | 1.78e-01 | 1.08e-03 |
| CYTOCHROME C MEDIATED APOPTOTIC RESPONSE | 12 | 2.25e-01 | 3.20e-01 | 0.3960 | -0.191000 | -0.146000 | -0.236000 | 1.49e-01 | 1.45e-01 | 2.51e-01 | 3.83e-01 | 1.57e-01 | 3.71e-01 | 3.83e-01 |
| CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND | 12 | 3.31e-01 | 4.28e-01 | 0.3960 | -0.091200 | -0.080200 | -0.373000 | 4.95e-02 | -2.28e-02 | 5.85e-01 | 6.31e-01 | 2.53e-02 | 7.67e-01 | 8.91e-01 |
| ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS | 18 | 2.02e-01 | 2.94e-01 | 0.3960 | -0.053300 | -0.168000 | -0.338000 | -1.05e-01 | -1.44e-02 | 6.95e-01 | 2.18e-01 | 1.29e-02 | 4.43e-01 | 9.16e-01 |
| PLASMA LIPOPROTEIN ASSEMBLY | 11 | 5.08e-01 | 5.94e-01 | 0.3960 | -0.026000 | 0.340000 | 0.031100 | 1.63e-01 | 1.13e-01 | 8.81e-01 | 5.09e-02 | 8.58e-01 | 3.48e-01 | 5.17e-01 |
| DERMATAN SULFATE BIOSYNTHESIS | 11 | 1.82e-01 | 2.74e-01 | 0.3960 | 0.041800 | 0.299000 | 0.172000 | -1.36e-01 | -1.33e-01 | 8.10e-01 | 8.65e-02 | 3.23e-01 | 4.36e-01 | 4.46e-01 |
| CD28 DEPENDENT VAV1 PATHWAY | 11 | 4.27e-01 | 5.21e-01 | 0.3950 | -0.345000 | -0.119000 | -0.028400 | -9.79e-02 | -1.14e-01 | 4.78e-02 | 4.96e-01 | 8.70e-01 | 5.74e-01 | 5.11e-01 |
| LYSINE CATABOLISM | 11 | 3.84e-01 | 4.81e-01 | 0.3950 | 0.052800 | 0.316000 | -0.141000 | 1.02e-01 | 1.52e-01 | 7.62e-01 | 6.93e-02 | 4.19e-01 | 5.57e-01 | 3.82e-01 |
| ERBB2 ACTIVATES PTK6 SIGNALING | 10 | 4.18e-01 | 5.15e-01 | 0.3950 | -0.021300 | 0.029200 | -0.221000 | -3.24e-01 | -3.04e-02 | 9.07e-01 | 8.73e-01 | 2.27e-01 | 7.62e-02 | 8.68e-01 |
| HS GAG BIOSYNTHESIS | 29 | 4.02e-03 | 1.38e-02 | 0.3940 | 0.002530 | 0.065100 | 0.222000 | -2.60e-01 | 1.85e-01 | 9.81e-01 | 5.44e-01 | 3.83e-02 | 1.54e-02 | 8.52e-02 |
| REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF | 56 | 5.67e-04 | 2.71e-03 | 0.3940 | -0.027300 | -0.229000 | -0.022700 | -2.91e-01 | 1.30e-01 | 7.24e-01 | 3.06e-03 | 7.69e-01 | 1.66e-04 | 9.20e-02 |
| TRIGLYCERIDE CATABOLISM | 14 | 3.01e-01 | 3.96e-01 | 0.3940 | -0.278000 | 0.047600 | -0.024900 | 2.67e-01 | -6.30e-02 | 7.19e-02 | 7.58e-01 | 8.72e-01 | 8.42e-02 | 6.83e-01 |
| TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER | 77 | 7.90e-06 | 6.03e-05 | 0.3930 | -0.137000 | 0.116000 | 0.124000 | 3.23e-01 | -4.81e-02 | 3.72e-02 | 7.79e-02 | 6.08e-02 | 9.40e-07 | 4.66e-01 |
| GLYCOSPHINGOLIPID METABOLISM | 37 | 2.93e-03 | 1.08e-02 | 0.3930 | 0.013600 | 0.050100 | 0.033600 | 2.65e-02 | 3.87e-01 | 8.86e-01 | 5.98e-01 | 7.24e-01 | 7.80e-01 | 4.62e-05 |
| FORMATION OF APOPTOSOME | 10 | 3.38e-01 | 4.34e-01 | 0.3920 | -0.117000 | -0.193000 | -0.279000 | 1.39e-01 | 7.51e-02 | 5.22e-01 | 2.92e-01 | 1.26e-01 | 4.46e-01 | 6.81e-01 |
| CHAPERONE MEDIATED AUTOPHAGY | 19 | 1.76e-01 | 2.65e-01 | 0.3920 | -0.115000 | 0.086200 | -0.096700 | 2.86e-01 | -2.05e-01 | 3.85e-01 | 5.16e-01 | 4.65e-01 | 3.09e-02 | 1.22e-01 |
| BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS | 11 | 4.23e-01 | 5.18e-01 | 0.3910 | 0.191000 | 0.121000 | 0.056000 | 3.13e-01 | -1.83e-02 | 2.73e-01 | 4.88e-01 | 7.48e-01 | 7.20e-02 | 9.16e-01 |
| NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 62 | 2.25e-04 | 1.19e-03 | 0.3910 | -0.186000 | 0.040300 | -0.019400 | 2.81e-01 | -1.91e-01 | 1.11e-02 | 5.83e-01 | 7.92e-01 | 1.28e-04 | 9.23e-03 |
| HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR | 48 | 2.68e-03 | 1.00e-02 | 0.3890 | -0.313000 | -0.183000 | -0.060200 | 9.16e-03 | -1.27e-01 | 1.77e-04 | 2.80e-02 | 4.71e-01 | 9.13e-01 | 1.29e-01 |
| NEURONAL SYSTEM | 362 | 3.97e-26 | 2.18e-24 | 0.3890 | 0.186000 | -0.108000 | 0.180000 | -2.08e-01 | 1.70e-01 | 1.27e-09 | 4.13e-04 | 4.22e-09 | 1.30e-11 | 2.78e-08 |
| ION TRANSPORT BY P TYPE ATPASES | 46 | 5.94e-03 | 1.90e-02 | 0.3890 | 0.192000 | 0.057100 | 0.110000 | -1.76e-01 | 2.61e-01 | 2.44e-02 | 5.03e-01 | 1.97e-01 | 3.91e-02 | 2.24e-03 |
| SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | 20 | 6.48e-02 | 1.27e-01 | 0.3880 | -0.079700 | 0.189000 | -0.171000 | -9.80e-03 | 2.81e-01 | 5.37e-01 | 1.44e-01 | 1.87e-01 | 9.40e-01 | 2.94e-02 |
| PHASE II CONJUGATION OF COMPOUNDS | 60 | 5.71e-04 | 2.72e-03 | 0.3870 | -0.125000 | 0.225000 | -0.014800 | 2.89e-01 | 1.50e-02 | 9.55e-02 | 2.54e-03 | 8.43e-01 | 1.11e-04 | 8.41e-01 |
| RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN | 37 | 1.35e-02 | 3.72e-02 | 0.3870 | -0.013200 | -0.291000 | 0.049100 | -1.69e-01 | -1.85e-01 | 8.90e-01 | 2.22e-03 | 6.05e-01 | 7.46e-02 | 5.14e-02 |
| ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | 30 | 1.43e-02 | 3.89e-02 | 0.3870 | -0.157000 | 0.052700 | 0.195000 | 2.91e-01 | 6.02e-04 | 1.36e-01 | 6.17e-01 | 6.45e-02 | 5.89e-03 | 9.95e-01 |
| MAPK6 MAPK4 SIGNALING | 83 | 2.13e-06 | 1.88e-05 | 0.3870 | -0.275000 | -0.128000 | -0.019700 | 1.75e-01 | -1.62e-01 | 1.52e-05 | 4.32e-02 | 7.57e-01 | 5.80e-03 | 1.06e-02 |
| NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | 10 | 5.19e-01 | 6.03e-01 | 0.3870 | 0.237000 | 0.286000 | -0.001000 | 3.23e-02 | 1.02e-01 | 1.95e-01 | 1.17e-01 | 9.96e-01 | 8.60e-01 | 5.78e-01 |
| HEPARAN SULFATE HEPARIN HS GAG METABOLISM | 51 | 3.12e-04 | 1.58e-03 | 0.3850 | 0.110000 | 0.140000 | 0.247000 | -1.78e-01 | 1.56e-01 | 1.74e-01 | 8.44e-02 | 2.32e-03 | 2.81e-02 | 5.40e-02 |
| RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX | 28 | 5.07e-02 | 1.05e-01 | 0.3850 | -0.139000 | 0.139000 | 0.119000 | 3.08e-01 | 1.52e-02 | 2.02e-01 | 2.04e-01 | 2.75e-01 | 4.80e-03 | 8.89e-01 |
| B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION | 45 | 6.19e-03 | 1.95e-02 | 0.3850 | -0.189000 | 0.029200 | -0.073700 | 2.49e-01 | -2.09e-01 | 2.81e-02 | 7.35e-01 | 3.92e-01 | 3.84e-03 | 1.53e-02 |
| SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | 12 | 4.10e-01 | 5.08e-01 | 0.3840 | 0.018500 | 0.208000 | -0.053600 | 1.13e-01 | 2.98e-01 | 9.12e-01 | 2.12e-01 | 7.48e-01 | 4.99e-01 | 7.42e-02 |
| ASSEMBLY OF THE HIV VIRION | 16 | 1.80e-01 | 2.71e-01 | 0.3830 | -0.212000 | -0.139000 | 0.064500 | 2.29e-01 | -1.61e-01 | 1.42e-01 | 3.35e-01 | 6.55e-01 | 1.12e-01 | 2.65e-01 |
| NETRIN 1 SIGNALING | 48 | 2.71e-03 | 1.02e-02 | 0.3830 | 0.176000 | -0.088600 | 0.213000 | -2.29e-01 | 1.00e-01 | 3.49e-02 | 2.89e-01 | 1.07e-02 | 6.14e-03 | 2.30e-01 |
| SIGNALING BY FGFR1 IN DISEASE | 32 | 7.42e-02 | 1.39e-01 | 0.3820 | -0.014700 | -0.202000 | -0.174000 | -2.72e-01 | 2.37e-02 | 8.86e-01 | 4.77e-02 | 8.77e-02 | 7.73e-03 | 8.17e-01 |
| TERMINATION OF TRANSLESION DNA SYNTHESIS | 31 | 3.71e-02 | 8.26e-02 | 0.3820 | -0.208000 | 0.073800 | 0.062600 | 2.58e-01 | -1.63e-01 | 4.47e-02 | 4.77e-01 | 5.47e-01 | 1.30e-02 | 1.15e-01 |
| MOLECULES ASSOCIATED WITH ELASTIC FIBRES | 31 | 6.06e-03 | 1.93e-02 | 0.3810 | 0.300000 | 0.217000 | -0.072500 | -2.06e-02 | 5.19e-02 | 3.81e-03 | 3.69e-02 | 4.85e-01 | 8.43e-01 | 6.17e-01 |
| LATE ENDOSOMAL MICROAUTOPHAGY | 30 | 3.31e-02 | 7.50e-02 | 0.3810 | -0.092900 | 0.057300 | 0.133000 | 3.29e-01 | -8.57e-02 | 3.78e-01 | 5.87e-01 | 2.09e-01 | 1.82e-03 | 4.17e-01 |
| NUCLEAR PORE COMPLEX NPC DISASSEMBLY | 31 | 4.94e-02 | 1.03e-01 | 0.3800 | 0.186000 | -0.175000 | 0.104000 | -1.51e-01 | 2.14e-01 | 7.37e-02 | 9.13e-02 | 3.14e-01 | 1.45e-01 | 3.97e-02 |
| REGULATED NECROSIS | 45 | 5.04e-03 | 1.66e-02 | 0.3800 | -0.224000 | -0.001270 | -0.084000 | 2.60e-01 | -1.39e-01 | 9.24e-03 | 9.88e-01 | 3.30e-01 | 2.53e-03 | 1.07e-01 |
| MYOGENESIS | 24 | 1.14e-01 | 1.95e-01 | 0.3800 | 0.111000 | -0.130000 | 0.030300 | -2.14e-01 | 2.62e-01 | 3.49e-01 | 2.71e-01 | 7.97e-01 | 7.02e-02 | 2.63e-02 |
| TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT | 18 | 1.86e-01 | 2.76e-01 | 0.3800 | -0.156000 | -0.144000 | -0.304000 | 8.01e-02 | 1.09e-03 | 2.52e-01 | 2.91e-01 | 2.53e-02 | 5.56e-01 | 9.94e-01 |
| INOSITOL PHOSPHATE METABOLISM | 46 | 1.71e-03 | 6.88e-03 | 0.3790 | 0.075300 | 0.168000 | 0.047900 | -1.30e-01 | 3.01e-01 | 3.77e-01 | 4.88e-02 | 5.74e-01 | 1.28e-01 | 4.15e-04 |
| SIGNALING BY KIT IN DISEASE | 20 | 1.84e-01 | 2.74e-01 | 0.3790 | 0.007820 | -0.333000 | -0.039700 | -1.63e-01 | 6.54e-02 | 9.52e-01 | 9.95e-03 | 7.59e-01 | 2.07e-01 | 6.13e-01 |
| DAP12 SIGNALING | 24 | 1.02e-01 | 1.79e-01 | 0.3780 | -0.293000 | -0.206000 | -0.113000 | 2.26e-02 | -3.69e-02 | 1.29e-02 | 8.07e-02 | 3.36e-01 | 8.48e-01 | 7.55e-01 |
| SUMOYLATION OF DNA METHYLATION PROTEINS | 15 | 3.33e-01 | 4.29e-01 | 0.3780 | -0.023600 | -0.269000 | 0.086600 | -2.03e-01 | -1.46e-01 | 8.74e-01 | 7.11e-02 | 5.61e-01 | 1.74e-01 | 3.26e-01 |
| SYNTHESIS OF PC | 26 | 1.48e-02 | 3.96e-02 | 0.3780 | 0.158000 | -0.063300 | -0.072400 | 1.53e-01 | 2.92e-01 | 1.63e-01 | 5.76e-01 | 5.23e-01 | 1.77e-01 | 9.92e-03 |
| DNA STRAND ELONGATION | 32 | 6.59e-02 | 1.28e-01 | 0.3780 | 0.026800 | 0.186000 | 0.078300 | 3.08e-01 | 8.33e-02 | 7.93e-01 | 6.89e-02 | 4.43e-01 | 2.61e-03 | 4.15e-01 |
| PENTOSE PHOSPHATE PATHWAY | 13 | 3.72e-01 | 4.70e-01 | 0.3780 | -0.105000 | 0.243000 | -0.183000 | 1.34e-01 | -1.47e-01 | 5.11e-01 | 1.30e-01 | 2.55e-01 | 4.04e-01 | 3.60e-01 |
| NEUROTRANSMITTER RELEASE CYCLE | 48 | 6.64e-03 | 2.08e-02 | 0.3770 | 0.286000 | -0.067700 | 0.082900 | -9.21e-02 | 2.01e-01 | 5.97e-04 | 4.17e-01 | 3.21e-01 | 2.70e-01 | 1.60e-02 |
| PCP CE PATHWAY | 88 | 5.69e-07 | 5.70e-06 | 0.3770 | -0.247000 | 0.038600 | 0.057200 | 2.70e-01 | -6.38e-02 | 6.45e-05 | 5.32e-01 | 3.54e-01 | 1.24e-05 | 3.01e-01 |
| AMINO ACIDS REGULATE MTORC1 | 51 | 8.35e-04 | 3.76e-03 | 0.3760 | 0.035200 | 0.019100 | 0.213000 | 2.14e-01 | 2.22e-01 | 6.64e-01 | 8.13e-01 | 8.58e-03 | 8.37e-03 | 6.18e-03 |
| SIGNALING BY FLT3 FUSION PROTEINS | 18 | 3.01e-01 | 3.96e-01 | 0.3760 | -0.013100 | -0.197000 | -0.123000 | -2.61e-01 | 1.37e-01 | 9.23e-01 | 1.47e-01 | 3.67e-01 | 5.54e-02 | 3.14e-01 |
| REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE | 75 | 6.24e-04 | 2.94e-03 | 0.3750 | -0.186000 | -0.207000 | -0.108000 | -2.12e-01 | -8.18e-02 | 5.28e-03 | 1.96e-03 | 1.06e-01 | 1.53e-03 | 2.21e-01 |
| SIGNALLING TO RAS | 17 | 9.78e-02 | 1.74e-01 | 0.3750 | -0.024400 | -0.325000 | -0.106000 | 2.43e-02 | 1.49e-01 | 8.62e-01 | 2.02e-02 | 4.48e-01 | 8.62e-01 | 2.87e-01 |
| GLYCOGEN METABOLISM | 25 | 6.31e-02 | 1.25e-01 | 0.3750 | -0.186000 | -0.043700 | -0.275000 | -6.07e-02 | 1.57e-01 | 1.08e-01 | 7.05e-01 | 1.74e-02 | 5.99e-01 | 1.73e-01 |
| PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION | 22 | 1.57e-01 | 2.45e-01 | 0.3740 | -0.170000 | 0.062700 | -0.320000 | -1.15e-02 | -6.87e-02 | 1.67e-01 | 6.11e-01 | 9.37e-03 | 9.25e-01 | 5.77e-01 |
| ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS | 26 | 9.92e-02 | 1.76e-01 | 0.3740 | -0.032000 | -0.212000 | -0.160000 | -2.02e-01 | 1.65e-01 | 7.78e-01 | 6.11e-02 | 1.59e-01 | 7.41e-02 | 1.45e-01 |
| ENOS ACTIVATION | 11 | 5.89e-01 | 6.61e-01 | 0.3740 | -0.181000 | 0.004300 | -0.322000 | 6.20e-04 | -6.04e-02 | 3.00e-01 | 9.80e-01 | 6.47e-02 | 9.97e-01 | 7.29e-01 |
| PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS | 19 | 1.12e-01 | 1.93e-01 | 0.3740 | -0.216000 | -0.105000 | 0.130000 | 2.09e-01 | -1.46e-01 | 1.03e-01 | 4.30e-01 | 3.27e-01 | 1.15e-01 | 2.70e-01 |
| CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND | 10 | 5.67e-01 | 6.44e-01 | 0.3730 | 0.288000 | 0.048000 | -0.002820 | -1.85e-01 | 1.40e-01 | 1.14e-01 | 7.93e-01 | 9.88e-01 | 3.12e-01 | 4.44e-01 |
| WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 | 13 | 3.02e-01 | 3.96e-01 | 0.3720 | -0.000872 | 0.291000 | 0.224000 | -2.04e-02 | 6.02e-02 | 9.96e-01 | 6.97e-02 | 1.62e-01 | 8.99e-01 | 7.07e-01 |
| MTOR SIGNALLING | 40 | 9.25e-03 | 2.77e-02 | 0.3720 | 0.029100 | 0.073000 | 0.144000 | 2.03e-01 | 2.66e-01 | 7.50e-01 | 4.24e-01 | 1.16e-01 | 2.66e-02 | 3.65e-03 |
| G2 M CHECKPOINTS | 128 | 7.34e-09 | 1.06e-07 | 0.3720 | -0.229000 | -0.000811 | -0.061000 | 2.59e-01 | -1.22e-01 | 7.73e-06 | 9.87e-01 | 2.34e-01 | 4.17e-07 | 1.71e-02 |
| AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | 14 | 2.38e-01 | 3.36e-01 | 0.3720 | 0.203000 | -0.156000 | 0.058300 | 1.03e-01 | 2.43e-01 | 1.89e-01 | 3.12e-01 | 7.06e-01 | 5.04e-01 | 1.16e-01 |
| NOTCH HLH TRANSCRIPTION PATHWAY | 28 | 4.92e-02 | 1.03e-01 | 0.3720 | 0.148000 | -0.151000 | -0.064300 | -2.73e-01 | -1.22e-01 | 1.76e-01 | 1.67e-01 | 5.56e-01 | 1.26e-02 | 2.62e-01 |
| DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX | 82 | 3.02e-06 | 2.55e-05 | 0.3710 | -0.294000 | 0.020900 | 0.001290 | 2.19e-01 | -5.57e-02 | 4.31e-06 | 7.44e-01 | 9.84e-01 | 6.17e-04 | 3.84e-01 |
| ERBB2 REGULATES CELL MOTILITY | 13 | 4.05e-01 | 5.02e-01 | 0.3700 | -0.118000 | -0.002600 | -0.230000 | -2.55e-01 | 7.13e-02 | 4.62e-01 | 9.87e-01 | 1.51e-01 | 1.12e-01 | 6.56e-01 |
| TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | 16 | 4.29e-01 | 5.23e-01 | 0.3690 | -0.313000 | -0.014600 | -0.148000 | 4.50e-02 | -1.18e-01 | 3.02e-02 | 9.20e-01 | 3.06e-01 | 7.55e-01 | 4.16e-01 |
| INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING | 41 | 1.68e-02 | 4.38e-02 | 0.3690 | -0.082700 | -0.191000 | -0.058700 | -2.88e-01 | 7.88e-02 | 3.59e-01 | 3.42e-02 | 5.16e-01 | 1.43e-03 | 3.83e-01 |
| TELOMERE MAINTENANCE | 75 | 4.57e-05 | 2.88e-04 | 0.3680 | -0.100000 | 0.056000 | -0.054100 | 2.94e-01 | -1.82e-01 | 1.33e-01 | 4.02e-01 | 4.18e-01 | 1.08e-05 | 6.48e-03 |
| ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION | 14 | 4.24e-01 | 5.19e-01 | 0.3680 | -0.106000 | -0.216000 | -0.117000 | -2.06e-01 | 1.46e-01 | 4.93e-01 | 1.62e-01 | 4.48e-01 | 1.81e-01 | 3.43e-01 |
| RAC1 GTPASE CYCLE | 176 | 1.48e-11 | 3.34e-10 | 0.3670 | 0.096200 | -0.103000 | -0.051600 | -2.85e-01 | 1.76e-01 | 2.79e-02 | 1.90e-02 | 2.38e-01 | 6.81e-11 | 6.03e-05 |
| INTERLEUKIN 2 FAMILY SIGNALING | 33 | 7.09e-02 | 1.35e-01 | 0.3670 | 0.010200 | -0.198000 | -0.055700 | -3.00e-01 | 4.79e-02 | 9.19e-01 | 4.92e-02 | 5.80e-01 | 2.90e-03 | 6.34e-01 |
| GABA RECEPTOR ACTIVATION | 53 | 1.16e-03 | 4.95e-03 | 0.3670 | -0.143000 | -0.162000 | -0.035100 | -2.85e-01 | 7.41e-02 | 7.12e-02 | 4.16e-02 | 6.58e-01 | 3.41e-04 | 3.51e-01 |
| GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER | 83 | 6.30e-05 | 3.80e-04 | 0.3670 | -0.086500 | 0.160000 | 0.121000 | 2.94e-01 | -1.96e-02 | 1.73e-01 | 1.16e-02 | 5.77e-02 | 3.78e-06 | 7.58e-01 |
| LAGGING STRAND SYNTHESIS | 20 | 2.16e-01 | 3.10e-01 | 0.3660 | -0.025200 | 0.151000 | -0.024700 | 3.28e-01 | -4.76e-02 | 8.45e-01 | 2.42e-01 | 8.48e-01 | 1.10e-02 | 7.13e-01 |
| FORMATION OF INCISION COMPLEX IN GG NER | 43 | 1.49e-02 | 3.98e-02 | 0.3660 | -0.091300 | 0.204000 | 0.151000 | 2.43e-01 | 4.79e-02 | 3.00e-01 | 2.10e-02 | 8.68e-02 | 5.83e-03 | 5.87e-01 |
| GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK | 16 | 3.40e-01 | 4.36e-01 | 0.3660 | -0.076300 | -0.296000 | -0.039800 | -1.75e-01 | 8.91e-02 | 5.97e-01 | 4.01e-02 | 7.83e-01 | 2.26e-01 | 5.37e-01 |
| INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | 20 | 2.28e-01 | 3.23e-01 | 0.3660 | -0.125000 | 0.138000 | 0.114000 | 2.93e-01 | -1.08e-02 | 3.32e-01 | 2.87e-01 | 3.76e-01 | 2.33e-02 | 9.33e-01 |
| RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION | 22 | 2.16e-01 | 3.10e-01 | 0.3660 | -0.087000 | -0.169000 | -0.062700 | -3.06e-01 | -1.37e-02 | 4.80e-01 | 1.71e-01 | 6.11e-01 | 1.30e-02 | 9.11e-01 |
| FATTY ACID METABOLISM | 143 | 2.04e-10 | 3.51e-09 | 0.3650 | 0.013100 | 0.222000 | -0.113000 | 2.17e-01 | 1.55e-01 | 7.87e-01 | 4.46e-06 | 1.97e-02 | 7.63e-06 | 1.42e-03 |
| ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS | 23 | 4.08e-02 | 8.86e-02 | 0.3650 | -0.212000 | -0.170000 | 0.057500 | 2.30e-01 | -5.38e-02 | 7.78e-02 | 1.58e-01 | 6.33e-01 | 5.59e-02 | 6.55e-01 |
| N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | 23 | 1.08e-01 | 1.88e-01 | 0.3650 | -0.122000 | -0.022900 | -0.183000 | -2.69e-01 | 1.09e-01 | 3.12e-01 | 8.50e-01 | 1.29e-01 | 2.54e-02 | 3.64e-01 |
| METABOLISM OF NUCLEOTIDES | 92 | 1.91e-06 | 1.72e-05 | 0.3650 | -0.194000 | 0.162000 | 0.046200 | 2.53e-01 | 5.49e-02 | 1.33e-03 | 7.12e-03 | 4.44e-01 | 2.72e-05 | 3.64e-01 |
| SURFACTANT METABOLISM | 15 | 4.71e-01 | 5.58e-01 | 0.3640 | -0.206000 | -0.021500 | -0.276000 | -1.13e-01 | -2.91e-02 | 1.67e-01 | 8.86e-01 | 6.44e-02 | 4.50e-01 | 8.45e-01 |
| RAF ACTIVATION | 34 | 6.17e-03 | 1.95e-02 | 0.3640 | -0.078300 | -0.219000 | 0.082600 | -1.37e-01 | 2.30e-01 | 4.30e-01 | 2.73e-02 | 4.05e-01 | 1.66e-01 | 2.04e-02 |
| BLOOD GROUP SYSTEMS BIOSYNTHESIS | 12 | 3.24e-01 | 4.21e-01 | 0.3640 | -0.094400 | 0.049300 | -0.110000 | 4.05e-02 | 3.28e-01 | 5.71e-01 | 7.68e-01 | 5.10e-01 | 8.08e-01 | 4.94e-02 |
| INTEGRIN SIGNALING | 24 | 1.43e-01 | 2.29e-01 | 0.3640 | -0.043300 | -0.219000 | -0.092500 | -2.14e-01 | 1.68e-01 | 7.14e-01 | 6.32e-02 | 4.33e-01 | 7.00e-02 | 1.54e-01 |
| TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS | 42 | 1.27e-02 | 3.54e-02 | 0.3640 | -0.205000 | 0.153000 | -0.222000 | 3.75e-02 | -1.27e-01 | 2.16e-02 | 8.67e-02 | 1.26e-02 | 6.74e-01 | 1.56e-01 |
| PROCESSING OF CAPPED INTRONLESS PRE MRNA | 28 | 3.07e-02 | 7.04e-02 | 0.3640 | -0.156000 | -0.048600 | 0.201000 | 1.35e-01 | -2.17e-01 | 1.54e-01 | 6.56e-01 | 6.62e-02 | 2.17e-01 | 4.69e-02 |
| THE NLRP3 INFLAMMASOME | 15 | 4.33e-01 | 5.26e-01 | 0.3630 | -0.126000 | -0.006160 | -0.312000 | -9.52e-02 | -9.93e-02 | 3.99e-01 | 9.67e-01 | 3.65e-02 | 5.23e-01 | 5.05e-01 |
| ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK | 28 | 3.88e-02 | 8.59e-02 | 0.3630 | 0.005690 | 0.041300 | 0.079600 | 1.46e-01 | 3.20e-01 | 9.58e-01 | 7.05e-01 | 4.66e-01 | 1.81e-01 | 3.35e-03 |
| CELL CELL JUNCTION ORGANIZATION | 46 | 1.76e-04 | 9.59e-04 | 0.3620 | -0.196000 | 0.021400 | -0.031300 | -2.79e-01 | 1.18e-01 | 2.15e-02 | 8.02e-01 | 7.14e-01 | 1.07e-03 | 1.68e-01 |
| RHOB GTPASE CYCLE | 67 | 5.67e-04 | 2.71e-03 | 0.3620 | 0.134000 | -0.085700 | 0.001200 | -2.49e-01 | 2.10e-01 | 5.76e-02 | 2.25e-01 | 9.86e-01 | 4.30e-04 | 3.01e-03 |
| RUNX3 REGULATES NOTCH SIGNALING | 13 | 2.62e-01 | 3.60e-01 | 0.3620 | 0.127000 | 0.095400 | -0.186000 | -2.66e-01 | 2.41e-02 | 4.27e-01 | 5.52e-01 | 2.47e-01 | 9.70e-02 | 8.81e-01 |
| PI 3K CASCADE FGFR2 | 14 | 3.61e-01 | 4.58e-01 | 0.3620 | 0.093800 | -0.198000 | -0.232000 | -1.44e-01 | 9.18e-02 | 5.43e-01 | 2.00e-01 | 1.33e-01 | 3.51e-01 | 5.52e-01 |
| DARPP 32 EVENTS | 23 | 4.86e-02 | 1.02e-01 | 0.3620 | -0.029200 | -0.080100 | 0.215000 | -6.54e-02 | 2.71e-01 | 8.08e-01 | 5.06e-01 | 7.47e-02 | 5.87e-01 | 2.46e-02 |
| RAP1 SIGNALLING | 15 | 4.14e-01 | 5.12e-01 | 0.3610 | 0.149000 | -0.133000 | 0.144000 | -1.02e-01 | 2.44e-01 | 3.18e-01 | 3.74e-01 | 3.33e-01 | 4.93e-01 | 1.02e-01 |
| NUCLEOTIDE EXCISION REPAIR | 109 | 1.20e-06 | 1.10e-05 | 0.3610 | -0.091800 | 0.130000 | 0.130000 | 2.95e-01 | -3.60e-02 | 9.80e-02 | 1.91e-02 | 1.93e-02 | 1.07e-07 | 5.17e-01 |
| GLYCOGEN SYNTHESIS | 14 | 3.62e-01 | 4.59e-01 | 0.3610 | -0.252000 | -0.056900 | -0.224000 | 7.18e-02 | 9.07e-02 | 1.03e-01 | 7.12e-01 | 1.47e-01 | 6.42e-01 | 5.57e-01 |
| ACTIVATION OF MATRIX METALLOPROTEINASES | 14 | 1.20e-01 | 2.03e-01 | 0.3610 | -0.067300 | 0.192000 | 0.017900 | -2.95e-01 | 4.09e-02 | 6.63e-01 | 2.14e-01 | 9.08e-01 | 5.63e-02 | 7.91e-01 |
| IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | 20 | 1.43e-01 | 2.28e-01 | 0.3610 | -0.086400 | -0.184000 | -0.291000 | 6.32e-02 | -6.13e-03 | 5.03e-01 | 1.55e-01 | 2.42e-02 | 6.25e-01 | 9.62e-01 |
| INACTIVATION OF CSF3 G CSF SIGNALING | 24 | 1.62e-01 | 2.51e-01 | 0.3600 | -0.237000 | -0.138000 | -0.213000 | 8.86e-02 | -3.64e-02 | 4.45e-02 | 2.42e-01 | 7.08e-02 | 4.52e-01 | 7.57e-01 |
| SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS | 12 | 5.48e-01 | 6.29e-01 | 0.3600 | 0.053000 | -0.255000 | -0.125000 | -1.75e-01 | 1.22e-01 | 7.50e-01 | 1.25e-01 | 4.55e-01 | 2.93e-01 | 4.63e-01 |
| THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | 26 | 7.80e-02 | 1.46e-01 | 0.3590 | -0.242000 | -0.193000 | 0.026300 | 9.11e-02 | -1.56e-01 | 3.30e-02 | 8.83e-02 | 8.17e-01 | 4.21e-01 | 1.68e-01 |
| YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | 11 | 5.88e-01 | 6.61e-01 | 0.3590 | 0.137000 | -0.065200 | -0.076100 | -2.77e-01 | 1.53e-01 | 4.30e-01 | 7.08e-01 | 6.62e-01 | 1.12e-01 | 3.79e-01 |
| TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS | 54 | 2.26e-03 | 8.72e-03 | 0.3590 | 0.175000 | -0.257000 | 0.069700 | -1.56e-01 | 5.60e-02 | 2.64e-02 | 1.11e-03 | 3.76e-01 | 4.70e-02 | 4.77e-01 |
| NS1 MEDIATED EFFECTS ON HOST PATHWAYS | 37 | 2.00e-02 | 5.04e-02 | 0.3590 | 0.029200 | -0.255000 | 0.100000 | -1.96e-01 | 1.20e-01 | 7.59e-01 | 7.36e-03 | 2.90e-01 | 3.88e-02 | 2.06e-01 |
| DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | 23 | 1.49e-01 | 2.36e-01 | 0.3590 | 0.054900 | -0.168000 | 0.116000 | -2.87e-01 | 4.68e-02 | 6.49e-01 | 1.64e-01 | 3.37e-01 | 1.74e-02 | 6.98e-01 |
| NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 26 | 7.08e-02 | 1.35e-01 | 0.3590 | -0.168000 | -0.050100 | 0.077700 | -5.31e-02 | -2.98e-01 | 1.38e-01 | 6.58e-01 | 4.93e-01 | 6.39e-01 | 8.48e-03 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 | 19 | 1.56e-01 | 2.45e-01 | 0.3580 | 0.016000 | -0.088900 | -0.322000 | -7.83e-02 | 1.01e-01 | 9.04e-01 | 5.02e-01 | 1.50e-02 | 5.55e-01 | 4.45e-01 |
| CYTOSOLIC TRNA AMINOACYLATION | 24 | 3.92e-02 | 8.63e-02 | 0.3580 | -0.141000 | 0.015600 | 0.041700 | 2.47e-01 | 2.13e-01 | 2.32e-01 | 8.95e-01 | 7.24e-01 | 3.61e-02 | 7.13e-02 |
| SUMOYLATION OF TRANSCRIPTION FACTORS | 16 | 5.72e-01 | 6.48e-01 | 0.3570 | -0.245000 | -0.078800 | -0.199000 | -2.61e-02 | -1.46e-01 | 8.97e-02 | 5.85e-01 | 1.69e-01 | 8.57e-01 | 3.14e-01 |
| EPHB MEDIATED FORWARD SIGNALING | 42 | 1.11e-02 | 3.17e-02 | 0.3570 | -0.107000 | -0.293000 | 0.064500 | -1.33e-01 | -8.96e-02 | 2.31e-01 | 1.01e-03 | 4.70e-01 | 1.37e-01 | 3.15e-01 |
| TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS | 10 | 5.88e-01 | 6.61e-01 | 0.3570 | 0.065600 | -0.045500 | -0.230000 | -2.24e-01 | 1.32e-01 | 7.20e-01 | 8.03e-01 | 2.07e-01 | 2.19e-01 | 4.71e-01 |
| TRANSFERRIN ENDOCYTOSIS AND RECYCLING | 26 | 4.03e-02 | 8.78e-02 | 0.3560 | 0.017100 | -0.008860 | 0.061800 | 2.51e-01 | 2.45e-01 | 8.80e-01 | 9.38e-01 | 5.85e-01 | 2.70e-02 | 3.07e-02 |
| HEDGEHOG ON STATE | 82 | 9.44e-06 | 7.02e-05 | 0.3560 | -0.294000 | -0.097500 | -0.049700 | 1.58e-01 | -5.95e-02 | 4.27e-06 | 1.27e-01 | 4.37e-01 | 1.37e-02 | 3.52e-01 |
| POTASSIUM CHANNELS | 89 | 4.99e-05 | 3.08e-04 | 0.3550 | 0.149000 | -0.045700 | 0.235000 | -1.15e-01 | 1.82e-01 | 1.54e-02 | 4.56e-01 | 1.27e-04 | 6.15e-02 | 3.01e-03 |
| PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | 237 | 9.24e-16 | 3.67e-14 | 0.3550 | -0.169000 | -0.015900 | 0.063900 | 1.36e-01 | -2.73e-01 | 7.43e-06 | 6.74e-01 | 9.08e-02 | 3.29e-04 | 5.27e-13 |
| SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX | 12 | 5.10e-01 | 5.96e-01 | 0.3540 | 0.242000 | -0.004160 | 0.165000 | 1.97e-01 | 2.62e-02 | 1.46e-01 | 9.80e-01 | 3.21e-01 | 2.37e-01 | 8.75e-01 |
| TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE | 13 | 5.25e-01 | 6.07e-01 | 0.3540 | -0.141000 | 0.236000 | 0.079100 | 1.98e-01 | -6.27e-02 | 3.79e-01 | 1.40e-01 | 6.21e-01 | 2.17e-01 | 6.95e-01 |
| TRP CHANNELS | 18 | 2.09e-01 | 3.02e-01 | 0.3530 | 0.317000 | -0.053400 | -0.037000 | -8.09e-02 | 1.16e-01 | 1.98e-02 | 6.95e-01 | 7.86e-01 | 5.53e-01 | 3.95e-01 |
| CIRCADIAN CLOCK | 67 | 1.16e-03 | 4.95e-03 | 0.3530 | 0.050500 | -0.237000 | 0.021900 | -2.41e-01 | 8.53e-02 | 4.75e-01 | 8.01e-04 | 7.56e-01 | 6.36e-04 | 2.27e-01 |
| RIP MEDIATED NFKB ACTIVATION VIA ZBP1 | 15 | 1.96e-01 | 2.88e-01 | 0.3530 | 0.101000 | -0.126000 | -0.299000 | -2.58e-02 | 9.11e-02 | 4.99e-01 | 3.97e-01 | 4.48e-02 | 8.63e-01 | 5.41e-01 |
| CDC42 GTPASE CYCLE | 152 | 8.83e-09 | 1.24e-07 | 0.3530 | 0.132000 | -0.112000 | 0.006080 | -2.73e-01 | 1.40e-01 | 4.93e-03 | 1.72e-02 | 8.97e-01 | 6.24e-09 | 2.89e-03 |
| INTERLEUKIN 12 FAMILY SIGNALING | 42 | 1.14e-02 | 3.23e-02 | 0.3510 | -0.193000 | -0.015600 | -0.097200 | 2.66e-01 | -7.61e-02 | 3.08e-02 | 8.61e-01 | 2.76e-01 | 2.91e-03 | 3.94e-01 |
| PHOSPHORYLATION OF THE APC C | 17 | 2.95e-01 | 3.92e-01 | 0.3500 | -0.223000 | 0.095000 | 0.091800 | 2.29e-01 | -5.69e-02 | 1.12e-01 | 4.98e-01 | 5.12e-01 | 1.02e-01 | 6.84e-01 |
| SIGNALING BY NTRK2 TRKB | 23 | 1.99e-01 | 2.91e-01 | 0.3490 | 0.060600 | -0.192000 | 0.094700 | -2.64e-01 | 5.21e-02 | 6.15e-01 | 1.12e-01 | 4.32e-01 | 2.81e-02 | 6.66e-01 |
| S PHASE | 152 | 4.47e-10 | 7.36e-09 | 0.3480 | -0.213000 | 0.075500 | -0.000865 | 2.64e-01 | -6.60e-03 | 5.72e-06 | 1.09e-01 | 9.85e-01 | 2.00e-08 | 8.88e-01 |
| DISEASES OF IMMUNE SYSTEM | 22 | 1.31e-01 | 2.14e-01 | 0.3480 | -0.106000 | -0.081000 | -0.289000 | -2.10e-03 | 1.39e-01 | 3.87e-01 | 5.11e-01 | 1.89e-02 | 9.86e-01 | 2.58e-01 |
| EXTRA NUCLEAR ESTROGEN SIGNALING | 65 | 7.65e-03 | 2.35e-02 | 0.3470 | -0.205000 | -0.187000 | -0.124000 | -1.52e-01 | -7.05e-02 | 4.25e-03 | 9.18e-03 | 8.38e-02 | 3.45e-02 | 3.26e-01 |
| E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS | 48 | 1.74e-02 | 4.48e-02 | 0.3470 | -0.229000 | -0.027600 | -0.165000 | 1.67e-01 | -1.10e-01 | 6.07e-03 | 7.40e-01 | 4.81e-02 | 4.53e-02 | 1.89e-01 |
| COPI MEDIATED ANTEROGRADE TRANSPORT | 90 | 3.03e-06 | 2.55e-05 | 0.3460 | 0.007690 | 0.000491 | 0.239000 | 1.52e-01 | 1.99e-01 | 9.00e-01 | 9.94e-01 | 8.74e-05 | 1.30e-02 | 1.10e-03 |
| SPRY REGULATION OF FGF SIGNALING | 16 | 3.50e-01 | 4.48e-01 | 0.3460 | 0.081300 | -0.023400 | 0.326000 | 7.76e-02 | 1.62e-02 | 5.73e-01 | 8.71e-01 | 2.38e-02 | 5.91e-01 | 9.11e-01 |
| UPTAKE AND FUNCTION OF ANTHRAX TOXINS | 11 | 5.56e-01 | 6.36e-01 | 0.3460 | 0.172000 | -0.146000 | -0.030800 | -6.11e-02 | 2.53e-01 | 3.24e-01 | 4.00e-01 | 8.59e-01 | 7.26e-01 | 1.46e-01 |
| PYRUVATE METABOLISM | 27 | 1.28e-01 | 2.11e-01 | 0.3460 | 0.041500 | 0.164000 | -0.021400 | 2.47e-01 | 1.72e-01 | 7.09e-01 | 1.40e-01 | 8.47e-01 | 2.64e-02 | 1.22e-01 |
| SIGNALLING TO ERKS | 31 | 2.02e-02 | 5.04e-02 | 0.3460 | -0.019200 | -0.234000 | -0.052500 | -4.42e-02 | 2.44e-01 | 8.53e-01 | 2.43e-02 | 6.13e-01 | 6.70e-01 | 1.85e-02 |
| PROTEIN FOLDING | 87 | 2.50e-06 | 2.15e-05 | 0.3450 | -0.192000 | -0.079200 | 0.082000 | 2.38e-01 | -1.14e-01 | 2.03e-03 | 2.02e-01 | 1.87e-01 | 1.26e-04 | 6.66e-02 |
| IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | 43 | 1.13e-02 | 3.21e-02 | 0.3450 | -0.069500 | 0.057100 | -0.200000 | 3.53e-02 | -2.64e-01 | 4.31e-01 | 5.17e-01 | 2.36e-02 | 6.89e-01 | 2.77e-03 |
| PHASE 2 PLATEAU PHASE | 11 | 3.37e-01 | 4.34e-01 | 0.3430 | 0.147000 | 0.154000 | 0.085300 | -2.10e-01 | -1.45e-01 | 3.98e-01 | 3.77e-01 | 6.24e-01 | 2.29e-01 | 4.05e-01 |
| GABA B RECEPTOR ACTIVATION | 39 | 1.30e-02 | 3.60e-02 | 0.3430 | -0.164000 | -0.183000 | 0.040200 | -2.34e-01 | 2.80e-02 | 7.56e-02 | 4.82e-02 | 6.64e-01 | 1.16e-02 | 7.62e-01 |
| ION CHANNEL TRANSPORT | 136 | 2.72e-06 | 2.32e-05 | 0.3430 | 0.226000 | 0.015100 | 0.095700 | -6.46e-02 | 2.30e-01 | 5.37e-06 | 7.61e-01 | 5.42e-02 | 1.94e-01 | 3.87e-06 |
| METALLOPROTEASE DUBS | 26 | 1.76e-01 | 2.66e-01 | 0.3420 | -0.235000 | 0.060100 | -0.143000 | 1.86e-01 | -5.03e-02 | 3.79e-02 | 5.96e-01 | 2.06e-01 | 9.99e-02 | 6.57e-01 |
| MICRORNA MIRNA BIOGENESIS | 24 | 1.20e-01 | 2.03e-01 | 0.3420 | -0.065400 | -0.142000 | -0.008690 | 1.65e-01 | -2.55e-01 | 5.79e-01 | 2.28e-01 | 9.41e-01 | 1.62e-01 | 3.08e-02 |
| SIGNALING BY BRAF AND RAF FUSIONS | 60 | 4.03e-03 | 1.38e-02 | 0.3410 | 0.062500 | -0.231000 | 0.041800 | -2.17e-01 | 9.80e-02 | 4.02e-01 | 1.94e-03 | 5.75e-01 | 3.64e-03 | 1.89e-01 |
| CTLA4 INHIBITORY SIGNALING | 20 | 1.68e-01 | 2.58e-01 | 0.3400 | -0.142000 | -0.201000 | -0.031900 | -1.39e-01 | 1.86e-01 | 2.72e-01 | 1.19e-01 | 8.05e-01 | 2.83e-01 | 1.49e-01 |
| AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | 24 | 2.54e-01 | 3.53e-01 | 0.3400 | 0.161000 | -0.004330 | 0.087600 | -1.74e-01 | 2.27e-01 | 1.72e-01 | 9.71e-01 | 4.58e-01 | 1.40e-01 | 5.38e-02 |
| PROTEIN UBIQUITINATION | 67 | 2.25e-03 | 8.69e-03 | 0.3400 | -0.268000 | -0.047600 | -0.146000 | 1.21e-01 | -7.42e-02 | 1.48e-04 | 5.00e-01 | 3.89e-02 | 8.79e-02 | 2.94e-01 |
| INTRA GOLGI TRAFFIC | 43 | 1.79e-02 | 4.58e-02 | 0.3400 | 0.077800 | -0.023800 | 0.143000 | -4.35e-02 | 2.94e-01 | 3.77e-01 | 7.87e-01 | 1.04e-01 | 6.21e-01 | 8.59e-04 |
| FCERI MEDIATED CA 2 MOBILIZATION | 25 | 1.24e-01 | 2.07e-01 | 0.3390 | -0.083100 | -0.155000 | -0.230000 | -7.07e-02 | 1.61e-01 | 4.72e-01 | 1.80e-01 | 4.64e-02 | 5.40e-01 | 1.64e-01 |
| DOWNSTREAM SIGNAL TRANSDUCTION | 29 | 1.20e-01 | 2.03e-01 | 0.3390 | 0.090300 | -0.195000 | -0.015000 | -1.69e-01 | 1.99e-01 | 4.00e-01 | 6.99e-02 | 8.89e-01 | 1.15e-01 | 6.33e-02 |
| DCC MEDIATED ATTRACTIVE SIGNALING | 14 | 2.81e-01 | 3.76e-01 | 0.3380 | -0.186000 | -0.137000 | 0.090800 | -2.20e-01 | 6.69e-02 | 2.28e-01 | 3.76e-01 | 5.56e-01 | 1.54e-01 | 6.65e-01 |
| REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS | 12 | 5.95e-01 | 6.66e-01 | 0.3380 | 0.113000 | -0.241000 | -0.071900 | -1.55e-01 | 1.20e-01 | 4.99e-01 | 1.49e-01 | 6.66e-01 | 3.53e-01 | 4.73e-01 |
| ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | 32 | 9.40e-02 | 1.68e-01 | 0.3370 | -0.167000 | -0.105000 | -0.029300 | -2.05e-01 | -1.78e-01 | 1.02e-01 | 3.03e-01 | 7.74e-01 | 4.49e-02 | 8.15e-02 |
| FORMATION OF RNA POL II ELONGATION COMPLEX | 57 | 2.27e-03 | 8.72e-03 | 0.3370 | -0.082800 | 0.043600 | 0.165000 | 1.98e-01 | -1.95e-01 | 2.80e-01 | 5.69e-01 | 3.12e-02 | 9.76e-03 | 1.08e-02 |
| CLEC7A DECTIN 1 SIGNALING | 93 | 5.02e-06 | 3.93e-05 | 0.3370 | -0.188000 | 0.009090 | -0.065800 | 2.71e-01 | -2.16e-03 | 1.70e-03 | 8.80e-01 | 2.73e-01 | 6.44e-06 | 9.71e-01 |
| MITOTIC G1 PHASE AND G1 S TRANSITION | 139 | 5.59e-09 | 8.16e-08 | 0.3360 | -0.202000 | 0.041000 | -0.012500 | 2.65e-01 | 2.33e-03 | 3.91e-05 | 4.05e-01 | 7.99e-01 | 6.87e-08 | 9.62e-01 |
| RNA POLYMERASE I TRANSCRIPTION | 65 | 2.68e-03 | 1.00e-02 | 0.3360 | -0.158000 | 0.074300 | 0.024000 | 2.30e-01 | -1.70e-01 | 2.79e-02 | 3.00e-01 | 7.38e-01 | 1.33e-03 | 1.81e-02 |
| CS DS DEGRADATION | 14 | 2.56e-01 | 3.54e-01 | 0.3350 | 0.165000 | 0.132000 | 0.120000 | -1.83e-01 | -1.41e-01 | 2.85e-01 | 3.94e-01 | 4.38e-01 | 2.35e-01 | 3.60e-01 |
| IRS MEDIATED SIGNALLING | 35 | 5.75e-02 | 1.16e-01 | 0.3350 | 0.092000 | -0.178000 | -0.107000 | -1.61e-01 | 1.87e-01 | 3.46e-01 | 6.90e-02 | 2.74e-01 | 9.97e-02 | 5.53e-02 |
| SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP | 59 | 7.78e-03 | 2.38e-02 | 0.3350 | -0.207000 | 0.106000 | -0.084900 | 1.96e-01 | -1.12e-01 | 5.98e-03 | 1.58e-01 | 2.60e-01 | 9.19e-03 | 1.38e-01 |
| DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS | 17 | 1.34e-01 | 2.19e-01 | 0.3350 | -0.078000 | -0.131000 | 0.147000 | 1.97e-01 | 1.69e-01 | 5.78e-01 | 3.49e-01 | 2.93e-01 | 1.61e-01 | 2.28e-01 |
| NR1H2 AND NR1H3 MEDIATED SIGNALING | 38 | 2.60e-02 | 6.15e-02 | 0.3340 | 0.175000 | -0.024500 | -0.099600 | -2.55e-01 | 7.55e-02 | 6.22e-02 | 7.94e-01 | 2.88e-01 | 6.60e-03 | 4.21e-01 |
| NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 20 | 1.71e-01 | 2.62e-01 | 0.3330 | 0.155000 | 0.119000 | -0.082300 | -2.31e-01 | 1.13e-01 | 2.30e-01 | 3.58e-01 | 5.24e-01 | 7.33e-02 | 3.82e-01 |
| HOST INTERACTIONS OF HIV FACTORS | 122 | 2.34e-08 | 3.03e-07 | 0.3330 | -0.203000 | -0.051200 | 0.032900 | 2.50e-01 | -5.80e-02 | 1.10e-04 | 3.30e-01 | 5.30e-01 | 1.81e-06 | 2.69e-01 |
| BIOLOGICAL OXIDATIONS | 120 | 8.55e-06 | 6.44e-05 | 0.3330 | -0.065800 | 0.227000 | 0.006760 | 2.29e-01 | 5.27e-02 | 2.14e-01 | 1.81e-05 | 8.98e-01 | 1.54e-05 | 3.19e-01 |
| INSULIN RECEPTOR SIGNALLING CASCADE | 40 | 4.19e-02 | 9.01e-02 | 0.3330 | 0.145000 | -0.130000 | -0.061300 | -1.71e-01 | 1.99e-01 | 1.12e-01 | 1.55e-01 | 5.03e-01 | 6.09e-02 | 2.96e-02 |
| L1CAM INTERACTIONS | 107 | 2.50e-06 | 2.15e-05 | 0.3330 | 0.085800 | -0.078000 | 0.176000 | -2.26e-01 | 1.23e-01 | 1.25e-01 | 1.64e-01 | 1.62e-03 | 5.58e-05 | 2.84e-02 |
| CELLULAR RESPONSE TO HEAT STRESS | 94 | 7.43e-04 | 3.44e-03 | 0.3320 | -0.145000 | -0.204000 | -0.075200 | -1.86e-01 | -8.87e-02 | 1.55e-02 | 6.37e-04 | 2.08e-01 | 1.89e-03 | 1.38e-01 |
| GLUCAGON SIGNALING IN METABOLIC REGULATION | 29 | 8.03e-02 | 1.49e-01 | 0.3320 | -0.168000 | -0.172000 | 0.063900 | -2.03e-01 | -8.56e-02 | 1.18e-01 | 1.10e-01 | 5.52e-01 | 5.82e-02 | 4.25e-01 |
| REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION | 10 | 5.07e-01 | 5.94e-01 | 0.3320 | 0.054700 | -0.241000 | -0.142000 | 6.64e-03 | 1.70e-01 | 7.65e-01 | 1.87e-01 | 4.36e-01 | 9.71e-01 | 3.51e-01 |
| RHOA GTPASE CYCLE | 142 | 2.34e-07 | 2.54e-06 | 0.3320 | 0.075300 | -0.109000 | -0.069300 | -2.47e-01 | 1.64e-01 | 1.22e-01 | 2.53e-02 | 1.55e-01 | 4.02e-07 | 7.55e-04 |
| ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING | 28 | 5.20e-02 | 1.07e-01 | 0.3320 | -0.070600 | -0.186000 | 0.176000 | 8.45e-02 | -1.79e-01 | 5.18e-01 | 8.78e-02 | 1.07e-01 | 4.39e-01 | 1.01e-01 |
| GLUCAGON TYPE LIGAND RECEPTORS | 23 | 2.15e-01 | 3.10e-01 | 0.3320 | -0.134000 | -0.047700 | 0.051300 | 1.87e-01 | -2.28e-01 | 2.65e-01 | 6.92e-01 | 6.71e-01 | 1.20e-01 | 5.84e-02 |
| COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM | 13 | 2.55e-01 | 3.53e-01 | 0.3310 | 0.045000 | -0.064700 | -0.268000 | 1.75e-01 | 3.82e-02 | 7.79e-01 | 6.87e-01 | 9.46e-02 | 2.76e-01 | 8.11e-01 |
| TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 43 | 3.39e-02 | 7.62e-02 | 0.3310 | 0.108000 | 0.092200 | 0.143000 | 2.52e-01 | -7.32e-02 | 2.20e-01 | 2.96e-01 | 1.05e-01 | 4.26e-03 | 4.07e-01 |
| TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | 43 | 3.93e-02 | 8.64e-02 | 0.3300 | -0.068700 | -0.156000 | -0.022500 | -2.79e-01 | -3.89e-02 | 4.36e-01 | 7.60e-02 | 7.99e-01 | 1.55e-03 | 6.59e-01 |
| TRANSMISSION ACROSS CHEMICAL SYNAPSES | 235 | 6.80e-12 | 1.67e-10 | 0.3300 | 0.151000 | -0.122000 | 0.138000 | -1.76e-01 | 1.46e-01 | 6.89e-05 | 1.32e-03 | 2.79e-04 | 3.49e-06 | 1.17e-04 |
| SIGNALING BY FLT3 ITD AND TKD MUTANTS | 15 | 5.32e-01 | 6.14e-01 | 0.3300 | 0.108000 | 0.118000 | 0.011300 | 9.48e-02 | 2.72e-01 | 4.69e-01 | 4.27e-01 | 9.40e-01 | 5.25e-01 | 6.80e-02 |
| TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN | 20 | 4.14e-01 | 5.12e-01 | 0.3290 | -0.062400 | -0.233000 | -0.003240 | -2.18e-01 | -5.09e-02 | 6.29e-01 | 7.13e-02 | 9.80e-01 | 9.12e-02 | 6.94e-01 |
| CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | 19 | 2.79e-01 | 3.75e-01 | 0.3290 | -0.142000 | 0.101000 | 0.083000 | 2.48e-01 | 9.91e-02 | 2.84e-01 | 4.46e-01 | 5.31e-01 | 6.17e-02 | 4.55e-01 |
| CELL EXTRACELLULAR MATRIX INTERACTIONS | 18 | 3.85e-01 | 4.82e-01 | 0.3290 | -0.106000 | 0.000619 | -0.293000 | -1.04e-01 | 1.74e-02 | 4.38e-01 | 9.96e-01 | 3.15e-02 | 4.45e-01 | 8.98e-01 |
| EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS | 31 | 1.12e-01 | 1.93e-01 | 0.3280 | 0.065100 | -0.234000 | 0.087000 | -1.74e-01 | 1.01e-01 | 5.30e-01 | 2.39e-02 | 4.02e-01 | 9.34e-02 | 3.29e-01 |
| REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS | 13 | 4.39e-01 | 5.29e-01 | 0.3270 | 0.112000 | 0.041300 | -0.159000 | -2.56e-01 | 4.51e-02 | 4.83e-01 | 7.97e-01 | 3.20e-01 | 1.10e-01 | 7.78e-01 |
| TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX | 18 | 2.20e-01 | 3.14e-01 | 0.3270 | -0.153000 | 0.053500 | -0.152000 | 7.90e-02 | 2.27e-01 | 2.60e-01 | 6.94e-01 | 2.64e-01 | 5.62e-01 | 9.58e-02 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 | 21 | 2.83e-01 | 3.79e-01 | 0.3270 | 0.016800 | -0.197000 | -0.228000 | -1.12e-01 | 5.88e-02 | 8.94e-01 | 1.17e-01 | 7.04e-02 | 3.76e-01 | 6.41e-01 |
| INTERLEUKIN 1 SIGNALING | 93 | 1.12e-05 | 8.10e-05 | 0.3270 | -0.127000 | 0.018500 | -0.017800 | 3.00e-01 | -2.33e-02 | 3.50e-02 | 7.59e-01 | 7.67e-01 | 5.98e-07 | 6.98e-01 |
| COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES | 58 | 2.18e-03 | 8.53e-03 | 0.3260 | -0.113000 | -0.067300 | 0.004040 | -2.20e-01 | -2.02e-01 | 1.38e-01 | 3.76e-01 | 9.58e-01 | 3.81e-03 | 7.68e-03 |
| CELL JUNCTION ORGANIZATION | 70 | 2.30e-04 | 1.21e-03 | 0.3260 | -0.149000 | -0.024500 | -0.113000 | -2.42e-01 | 1.10e-01 | 3.06e-02 | 7.23e-01 | 1.04e-01 | 4.77e-04 | 1.13e-01 |
| TRANSCRIPTION OF THE HIV GENOME | 67 | 2.07e-03 | 8.18e-03 | 0.3250 | -0.149000 | 0.045200 | 0.068300 | 2.29e-01 | -1.56e-01 | 3.51e-02 | 5.22e-01 | 3.34e-01 | 1.18e-03 | 2.68e-02 |
| TRANSCRIPTIONAL REGULATION BY RUNX2 | 105 | 1.98e-05 | 1.33e-04 | 0.3250 | -0.230000 | -0.102000 | -0.018800 | 1.36e-01 | -1.54e-01 | 4.71e-05 | 6.98e-02 | 7.39e-01 | 1.64e-02 | 6.56e-03 |
| AGGREPHAGY | 34 | 6.54e-02 | 1.27e-01 | 0.3250 | -0.084100 | 0.010700 | 0.119000 | 2.41e-01 | -1.63e-01 | 3.96e-01 | 9.14e-01 | 2.31e-01 | 1.51e-02 | 1.01e-01 |
| FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX | 44 | 4.73e-02 | 9.94e-02 | 0.3250 | -0.158000 | -0.036900 | -0.130000 | -1.83e-01 | -1.70e-01 | 6.95e-02 | 6.72e-01 | 1.35e-01 | 3.62e-02 | 5.06e-02 |
| NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION | 58 | 1.02e-02 | 2.99e-02 | 0.3250 | 0.131000 | -0.172000 | 0.099500 | -1.98e-01 | 9.74e-02 | 8.38e-02 | 2.33e-02 | 1.90e-01 | 9.06e-03 | 2.00e-01 |
| SIGNALING BY NODAL | 15 | 5.60e-01 | 6.38e-01 | 0.3240 | 0.191000 | -0.117000 | -0.012000 | -1.82e-01 | 1.47e-01 | 2.00e-01 | 4.35e-01 | 9.36e-01 | 2.22e-01 | 3.23e-01 |
| RHOC GTPASE CYCLE | 73 | 8.33e-04 | 3.76e-03 | 0.3230 | 0.039900 | -0.049700 | -0.133000 | -2.48e-01 | 1.46e-01 | 5.56e-01 | 4.63e-01 | 4.95e-02 | 2.54e-04 | 3.08e-02 |
| REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | 29 | 1.66e-01 | 2.56e-01 | 0.3230 | 0.130000 | -0.176000 | 0.134000 | -1.37e-01 | 1.39e-01 | 2.25e-01 | 1.01e-01 | 2.11e-01 | 2.01e-01 | 1.94e-01 |
| INTERLEUKIN 37 SIGNALING | 17 | 2.98e-01 | 3.94e-01 | 0.3230 | 0.118000 | -0.102000 | -0.250000 | -1.30e-01 | 8.81e-03 | 4.00e-01 | 4.65e-01 | 7.40e-02 | 3.53e-01 | 9.50e-01 |
| RND2 GTPASE CYCLE | 38 | 1.60e-02 | 4.24e-02 | 0.3230 | 0.051500 | 0.005430 | -0.031600 | -3.11e-01 | -6.24e-02 | 5.83e-01 | 9.54e-01 | 7.36e-01 | 9.21e-04 | 5.06e-01 |
| METAL ION SLC TRANSPORTERS | 23 | 2.89e-01 | 3.84e-01 | 0.3230 | 0.251000 | -0.020000 | 0.028300 | -1.65e-01 | 1.12e-01 | 3.73e-02 | 8.68e-01 | 8.15e-01 | 1.71e-01 | 3.52e-01 |
| ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION | 30 | 2.20e-01 | 3.14e-01 | 0.3220 | -0.181000 | 0.046900 | -0.137000 | 1.48e-01 | -1.68e-01 | 8.58e-02 | 6.56e-01 | 1.93e-01 | 1.62e-01 | 1.11e-01 |
| SIGNALING BY VEGF | 100 | 4.80e-05 | 2.99e-04 | 0.3220 | 0.001420 | -0.173000 | -0.032400 | -2.06e-01 | 1.75e-01 | 9.80e-01 | 2.85e-03 | 5.76e-01 | 3.83e-04 | 2.52e-03 |
| ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 | 10 | 8.20e-01 | 8.54e-01 | 0.3220 | -0.136000 | -0.204000 | -0.153000 | -1.41e-01 | 1.60e-02 | 4.58e-01 | 2.64e-01 | 4.01e-01 | 4.39e-01 | 9.30e-01 |
| NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION | 176 | 2.52e-09 | 3.92e-08 | 0.3220 | 0.083000 | -0.155000 | 0.143000 | -1.98e-01 | 1.15e-01 | 5.79e-02 | 3.89e-04 | 1.09e-03 | 6.20e-06 | 8.86e-03 |
| SIGNALING BY NOTCH3 | 48 | 1.67e-02 | 4.36e-02 | 0.3210 | -0.109000 | -0.091300 | 0.002830 | -1.80e-01 | -2.25e-01 | 1.90e-01 | 2.74e-01 | 9.73e-01 | 3.11e-02 | 6.98e-03 |
| G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | 23 | 1.22e-01 | 2.05e-01 | 0.3210 | -0.158000 | -0.214000 | -0.012900 | 1.66e-01 | -6.70e-02 | 1.90e-01 | 7.50e-02 | 9.15e-01 | 1.68e-01 | 5.78e-01 |
| SMOOTH MUSCLE CONTRACTION | 32 | 2.12e-02 | 5.24e-02 | 0.3210 | 0.217000 | 0.175000 | -0.068600 | 1.15e-01 | -8.57e-02 | 3.34e-02 | 8.67e-02 | 5.02e-01 | 2.60e-01 | 4.01e-01 |
| SHC1 EVENTS IN ERBB2 SIGNALING | 20 | 4.25e-01 | 5.20e-01 | 0.3210 | 0.004470 | -0.126000 | -0.182000 | -2.21e-01 | 7.13e-02 | 9.72e-01 | 3.30e-01 | 1.59e-01 | 8.76e-02 | 5.81e-01 |
| METABOLISM OF FOLATE AND PTERINES | 15 | 5.38e-01 | 6.19e-01 | 0.3200 | -0.075100 | 0.094800 | 0.034500 | 2.94e-01 | -1.49e-02 | 6.15e-01 | 5.25e-01 | 8.17e-01 | 4.86e-02 | 9.20e-01 |
| RHO GTPASES ACTIVATE PKNS | 45 | 5.36e-02 | 1.08e-01 | 0.3200 | -0.175000 | 0.093700 | -0.142000 | 1.70e-01 | -1.18e-01 | 4.21e-02 | 2.77e-01 | 1.00e-01 | 4.79e-02 | 1.70e-01 |
| RHOQ GTPASE CYCLE | 57 | 2.01e-02 | 5.04e-02 | 0.3200 | 0.061400 | -0.164000 | -0.095000 | -2.46e-01 | 4.45e-02 | 4.23e-01 | 3.20e-02 | 2.15e-01 | 1.33e-03 | 5.61e-01 |
| SIGNALING BY NOTCH1 | 75 | 3.06e-03 | 1.11e-02 | 0.3190 | -0.076400 | -0.158000 | -0.035200 | -2.46e-01 | -9.87e-02 | 2.53e-01 | 1.82e-02 | 5.98e-01 | 2.37e-04 | 1.40e-01 |
| NF KB IS ACTIVATED AND SIGNALS SURVIVAL | 12 | 6.60e-01 | 7.14e-01 | 0.3190 | -0.070600 | 0.099500 | -0.082100 | 2.12e-01 | -1.88e-01 | 6.72e-01 | 5.50e-01 | 6.22e-01 | 2.04e-01 | 2.60e-01 |
| REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | 85 | 1.21e-05 | 8.69e-05 | 0.3180 | 0.168000 | 0.234000 | -0.109000 | 7.06e-02 | 4.12e-02 | 7.59e-03 | 1.98e-04 | 8.28e-02 | 2.61e-01 | 5.12e-01 |
| FGFR1 MUTANT RECEPTOR ACTIVATION | 25 | 2.84e-01 | 3.79e-01 | 0.3180 | 0.051600 | -0.109000 | -0.121000 | -2.62e-01 | 5.57e-02 | 6.55e-01 | 3.47e-01 | 2.94e-01 | 2.33e-02 | 6.30e-01 |
| PHASE 4 RESTING MEMBRANE POTENTIAL | 13 | 3.28e-01 | 4.25e-01 | 0.3180 | -0.092600 | 0.049100 | 0.195000 | -1.17e-01 | 1.95e-01 | 5.63e-01 | 7.59e-01 | 2.23e-01 | 4.64e-01 | 2.24e-01 |
| SIGNALING BY NTRK3 TRKC | 16 | 5.17e-01 | 6.03e-01 | 0.3170 | 0.009240 | -0.208000 | 0.064000 | -2.03e-01 | -1.10e-01 | 9.49e-01 | 1.50e-01 | 6.58e-01 | 1.60e-01 | 4.46e-01 |
| SIGNALING BY FGFR2 IN DISEASE | 34 | 7.29e-02 | 1.38e-01 | 0.3170 | -0.124000 | -0.110000 | -0.051900 | 1.96e-01 | -1.80e-01 | 2.12e-01 | 2.67e-01 | 6.00e-01 | 4.82e-02 | 7.00e-02 |
| SEMAPHORIN INTERACTIONS | 64 | 1.14e-02 | 3.23e-02 | 0.3170 | -0.003280 | -0.197000 | -0.020200 | -2.23e-01 | -1.09e-01 | 9.64e-01 | 6.53e-03 | 7.80e-01 | 2.09e-03 | 1.32e-01 |
| HYALURONAN METABOLISM | 15 | 3.61e-01 | 4.58e-01 | 0.3170 | 0.178000 | 0.165000 | 0.099400 | -1.77e-01 | -5.83e-03 | 2.31e-01 | 2.68e-01 | 5.05e-01 | 2.36e-01 | 9.69e-01 |
| SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS | 11 | 6.11e-01 | 6.78e-01 | 0.3170 | 0.120000 | -0.237000 | 0.058900 | -6.90e-02 | -1.47e-01 | 4.91e-01 | 1.74e-01 | 7.35e-01 | 6.92e-01 | 3.99e-01 |
| INTERLEUKIN 17 SIGNALING | 66 | 7.12e-03 | 2.22e-02 | 0.3170 | 0.167000 | -0.128000 | 0.032600 | -1.61e-01 | 1.70e-01 | 1.87e-02 | 7.30e-02 | 6.47e-01 | 2.41e-02 | 1.67e-02 |
| TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE | 38 | 8.72e-02 | 1.59e-01 | 0.3160 | -0.115000 | 0.095700 | 0.066200 | 2.54e-01 | -9.14e-02 | 2.18e-01 | 3.08e-01 | 4.80e-01 | 6.72e-03 | 3.30e-01 |
| METABOLISM OF PORPHYRINS | 19 | 4.48e-01 | 5.39e-01 | 0.3160 | 0.082800 | 0.047000 | 0.153000 | 2.10e-01 | 1.52e-01 | 5.32e-01 | 7.23e-01 | 2.47e-01 | 1.13e-01 | 2.52e-01 |
| CHROMOSOME MAINTENANCE | 97 | 9.24e-05 | 5.38e-04 | 0.3160 | -0.078100 | 0.068200 | -0.056400 | 2.52e-01 | -1.49e-01 | 1.84e-01 | 2.46e-01 | 3.37e-01 | 1.82e-05 | 1.13e-02 |
| ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS | 22 | 3.65e-01 | 4.61e-01 | 0.3150 | 0.166000 | -0.095900 | -0.026900 | -1.85e-01 | 1.67e-01 | 1.79e-01 | 4.36e-01 | 8.27e-01 | 1.33e-01 | 1.75e-01 |
| GLYCOSAMINOGLYCAN METABOLISM | 113 | 1.02e-05 | 7.55e-05 | 0.3140 | 0.107000 | 0.159000 | 0.176000 | -1.06e-01 | 1.41e-01 | 5.01e-02 | 3.61e-03 | 1.25e-03 | 5.20e-02 | 9.51e-03 |
| FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF | 14 | 3.48e-01 | 4.45e-01 | 0.3140 | 0.200000 | 0.219000 | -0.077400 | -6.77e-02 | -2.68e-05 | 1.94e-01 | 1.56e-01 | 6.16e-01 | 6.61e-01 | 1.00e+00 |
| INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING | 75 | 2.46e-03 | 9.38e-03 | 0.3130 | -0.092300 | -0.086700 | -0.273000 | -8.25e-02 | 2.73e-02 | 1.67e-01 | 1.95e-01 | 4.47e-05 | 2.17e-01 | 6.83e-01 |
| INTERFERON SIGNALING | 163 | 3.65e-06 | 3.00e-05 | 0.3130 | -0.065300 | -0.211000 | -0.153000 | -8.33e-02 | -1.36e-01 | 1.51e-01 | 3.46e-06 | 7.37e-04 | 6.68e-02 | 2.76e-03 |
| NEGATIVE REGULATION OF THE PI3K AKT NETWORK | 88 | 4.84e-04 | 2.38e-03 | 0.3120 | 0.107000 | -0.131000 | -0.064700 | -1.71e-01 | 1.88e-01 | 8.20e-02 | 3.43e-02 | 2.94e-01 | 5.48e-03 | 2.30e-03 |
| TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES | 37 | 1.07e-01 | 1.87e-01 | 0.3120 | 0.069900 | 0.149000 | 0.005200 | 2.37e-01 | 1.18e-01 | 4.62e-01 | 1.16e-01 | 9.56e-01 | 1.27e-02 | 2.13e-01 |
| ACTIVATION OF AMPK DOWNSTREAM OF NMDARS | 20 | 1.87e-01 | 2.77e-01 | 0.3120 | -0.051000 | -0.066400 | 0.198000 | 1.96e-01 | 1.12e-01 | 6.93e-01 | 6.07e-01 | 1.25e-01 | 1.28e-01 | 3.87e-01 |
| HS GAG DEGRADATION | 20 | 4.38e-01 | 5.29e-01 | 0.3120 | 0.156000 | 0.104000 | 0.206000 | -9.99e-02 | 9.70e-02 | 2.28e-01 | 4.19e-01 | 1.10e-01 | 4.39e-01 | 4.53e-01 |
| RET SIGNALING | 35 | 1.22e-01 | 2.05e-01 | 0.3120 | 0.102000 | -0.117000 | 0.093300 | -2.36e-01 | 9.17e-02 | 2.96e-01 | 2.29e-01 | 3.40e-01 | 1.57e-02 | 3.48e-01 |
| SIALIC ACID METABOLISM | 32 | 1.73e-01 | 2.63e-01 | 0.3110 | 0.096600 | 0.174000 | 0.037200 | -1.79e-02 | 2.36e-01 | 3.45e-01 | 8.87e-02 | 7.16e-01 | 8.61e-01 | 2.10e-02 |
| SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS | 41 | 3.45e-02 | 7.76e-02 | 0.3110 | 0.013400 | -0.239000 | 0.082800 | -1.32e-01 | 1.24e-01 | 8.82e-01 | 8.12e-03 | 3.59e-01 | 1.44e-01 | 1.71e-01 |
| NONHOMOLOGOUS END JOINING NHEJ | 41 | 1.68e-01 | 2.58e-01 | 0.3110 | -0.147000 | -0.082200 | -0.201000 | -7.96e-03 | -1.67e-01 | 1.03e-01 | 3.62e-01 | 2.57e-02 | 9.30e-01 | 6.50e-02 |
| REGULATED PROTEOLYSIS OF P75NTR | 12 | 5.96e-01 | 6.66e-01 | 0.3100 | -0.030900 | -0.075100 | -0.299000 | -1.38e-02 | 1.48e-02 | 8.53e-01 | 6.53e-01 | 7.30e-02 | 9.34e-01 | 9.29e-01 |
| ABC FAMILY PROTEINS MEDIATED TRANSPORT | 92 | 2.60e-05 | 1.71e-04 | 0.3100 | -0.190000 | -0.012300 | 0.043600 | 2.39e-01 | -2.33e-02 | 1.62e-03 | 8.39e-01 | 4.70e-01 | 7.49e-05 | 7.00e-01 |
| A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | 26 | 2.71e-01 | 3.69e-01 | 0.3100 | 0.153000 | 0.192000 | 0.147000 | -6.76e-02 | 9.64e-02 | 1.78e-01 | 8.98e-02 | 1.94e-01 | 5.51e-01 | 3.95e-01 |
| LDL CLEARANCE | 15 | 4.54e-01 | 5.42e-01 | 0.3100 | -0.148000 | -0.134000 | -0.014500 | -2.04e-01 | 1.20e-01 | 3.22e-01 | 3.68e-01 | 9.23e-01 | 1.72e-01 | 4.22e-01 |
| SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER | 59 | 1.67e-02 | 4.36e-02 | 0.3090 | -0.069600 | -0.121000 | -0.041300 | -2.06e-01 | -1.79e-01 | 3.56e-01 | 1.09e-01 | 5.84e-01 | 6.34e-03 | 1.75e-02 |
| TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES | 11 | 5.00e-01 | 5.88e-01 | 0.3090 | 0.175000 | -0.169000 | -0.183000 | -4.35e-02 | -2.68e-02 | 3.15e-01 | 3.33e-01 | 2.92e-01 | 8.03e-01 | 8.78e-01 |
| CELLULAR RESPONSES TO EXTERNAL STIMULI | 593 | 8.78e-29 | 5.32e-27 | 0.3080 | -0.175000 | -0.020600 | -0.040500 | 2.05e-01 | -1.42e-01 | 4.24e-13 | 3.93e-01 | 9.40e-02 | 1.98e-17 | 4.00e-09 |
| SHC1 EVENTS IN ERBB4 SIGNALING | 12 | 6.54e-01 | 7.10e-01 | 0.3080 | -0.070800 | -0.032200 | -0.238000 | -1.27e-01 | 1.27e-01 | 6.71e-01 | 8.47e-01 | 1.54e-01 | 4.48e-01 | 4.45e-01 |
| REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION | 30 | 1.56e-01 | 2.45e-01 | 0.3080 | 0.185000 | -0.158000 | 0.172000 | -2.03e-02 | 7.39e-02 | 7.97e-02 | 1.34e-01 | 1.03e-01 | 8.48e-01 | 4.84e-01 |
| IRE1ALPHA ACTIVATES CHAPERONES | 49 | 2.72e-02 | 6.36e-02 | 0.3070 | -0.062000 | -0.269000 | 0.010700 | -1.33e-01 | 2.68e-02 | 4.53e-01 | 1.15e-03 | 8.97e-01 | 1.07e-01 | 7.45e-01 |
| POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION | 26 | 1.80e-01 | 2.71e-01 | 0.3070 | 0.028600 | -0.198000 | 0.046000 | -1.08e-01 | 2.01e-01 | 8.01e-01 | 8.00e-02 | 6.85e-01 | 3.40e-01 | 7.64e-02 |
| SIGNALING BY TGFB FAMILY MEMBERS | 97 | 1.10e-03 | 4.71e-03 | 0.3070 | -0.143000 | -0.134000 | -0.105000 | -2.11e-01 | -2.09e-02 | 1.51e-02 | 2.24e-02 | 7.46e-02 | 3.36e-04 | 7.22e-01 |
| APOPTOTIC EXECUTION PHASE | 43 | 1.04e-02 | 3.05e-02 | 0.3070 | -0.063100 | 0.114000 | -0.128000 | -1.76e-01 | 1.73e-01 | 4.74e-01 | 1.95e-01 | 1.47e-01 | 4.58e-02 | 4.99e-02 |
| SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R | 40 | 5.77e-02 | 1.16e-01 | 0.3070 | 0.130000 | -0.119000 | -0.139000 | -1.60e-01 | 1.34e-01 | 1.56e-01 | 1.93e-01 | 1.29e-01 | 7.92e-02 | 1.41e-01 |
| FRS MEDIATED FGFR2 SIGNALING | 16 | 3.39e-01 | 4.35e-01 | 0.3070 | 0.041400 | -0.139000 | -0.228000 | -6.86e-03 | 1.45e-01 | 7.75e-01 | 3.35e-01 | 1.15e-01 | 9.62e-01 | 3.14e-01 |
| NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS | 18 | 2.31e-01 | 3.27e-01 | 0.3070 | -0.129000 | -0.172000 | 0.180000 | 1.02e-01 | -6.93e-02 | 3.42e-01 | 2.06e-01 | 1.86e-01 | 4.54e-01 | 6.11e-01 |
| NEGATIVE REGULATION OF FGFR1 SIGNALING | 25 | 3.79e-01 | 4.76e-01 | 0.3060 | 0.182000 | -0.030900 | 0.210000 | 5.11e-02 | 1.14e-01 | 1.16e-01 | 7.89e-01 | 6.90e-02 | 6.58e-01 | 3.22e-01 |
| PEROXISOMAL PROTEIN IMPORT | 58 | 5.42e-03 | 1.77e-02 | 0.3060 | -0.047500 | 0.110000 | -0.094800 | 2.53e-01 | 7.78e-02 | 5.31e-01 | 1.47e-01 | 2.12e-01 | 8.44e-04 | 3.05e-01 |
| G ALPHA 12 13 SIGNALLING EVENTS | 74 | 2.52e-03 | 9.59e-03 | 0.3060 | 0.062100 | -0.131000 | 0.036700 | -1.73e-01 | 2.02e-01 | 3.56e-01 | 5.10e-02 | 5.85e-01 | 9.91e-03 | 2.63e-03 |
| N GLYCAN ANTENNAE ELONGATION | 15 | 6.09e-01 | 6.77e-01 | 0.3050 | -0.046100 | -0.060700 | -0.152000 | -2.53e-01 | 1.60e-02 | 7.57e-01 | 6.84e-01 | 3.09e-01 | 8.93e-02 | 9.15e-01 |
| DEREGULATED CDK5 TRIGGERS MULTIPLE NEURODEGENERATIVE PATHWAYS IN ALZHEIMER S DISEASE MODELS | 19 | 5.46e-01 | 6.27e-01 | 0.3050 | 0.247000 | 0.063800 | 0.163000 | -4.07e-03 | 3.77e-02 | 6.19e-02 | 6.30e-01 | 2.20e-01 | 9.75e-01 | 7.76e-01 |
| OPIOID SIGNALLING | 85 | 3.06e-04 | 1.57e-03 | 0.3050 | 0.037000 | -0.157000 | 0.137000 | -1.70e-01 | 1.38e-01 | 5.55e-01 | 1.25e-02 | 2.89e-02 | 6.72e-03 | 2.77e-02 |
| VLDLR INTERNALISATION AND DEGRADATION | 11 | 8.33e-01 | 8.63e-01 | 0.3040 | 0.143000 | 0.138000 | 0.170000 | -2.62e-02 | 1.53e-01 | 4.12e-01 | 4.29e-01 | 3.30e-01 | 8.80e-01 | 3.79e-01 |
| NUCLEAR ENVELOPE BREAKDOWN | 48 | 6.18e-02 | 1.22e-01 | 0.3040 | 0.168000 | -0.106000 | 0.152000 | -9.15e-02 | 1.46e-01 | 4.43e-02 | 2.02e-01 | 6.88e-02 | 2.73e-01 | 8.03e-02 |
| SIGNALING BY CSF3 G CSF | 29 | 1.70e-01 | 2.60e-01 | 0.3030 | -0.192000 | -0.094000 | -0.190000 | 9.79e-02 | 2.33e-02 | 7.35e-02 | 3.81e-01 | 7.62e-02 | 3.62e-01 | 8.28e-01 |
| REGULATION OF FZD BY UBIQUITINATION | 19 | 2.88e-01 | 3.83e-01 | 0.3030 | -0.132000 | 0.096400 | -0.172000 | -1.42e-01 | 1.24e-01 | 3.18e-01 | 4.67e-01 | 1.95e-01 | 2.82e-01 | 3.50e-01 |
| RECYCLING PATHWAY OF L1 | 40 | 8.78e-02 | 1.60e-01 | 0.3030 | 0.085500 | 0.030000 | 0.215000 | -6.90e-02 | 1.80e-01 | 3.49e-01 | 7.43e-01 | 1.85e-02 | 4.51e-01 | 4.84e-02 |
| ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | 15 | 6.30e-01 | 6.94e-01 | 0.3020 | -0.111000 | -0.173000 | -0.187000 | 4.84e-02 | -1.07e-01 | 4.57e-01 | 2.45e-01 | 2.09e-01 | 7.45e-01 | 4.75e-01 |
| PI3K AKT SIGNALING IN CANCER | 83 | 1.25e-03 | 5.20e-03 | 0.3020 | 0.150000 | -0.097600 | -0.078700 | -1.72e-01 | 1.53e-01 | 1.83e-02 | 1.25e-01 | 2.15e-01 | 6.89e-03 | 1.59e-02 |
| VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS | 35 | 6.45e-02 | 1.27e-01 | 0.3020 | -0.165000 | -0.185000 | 0.070400 | -1.54e-01 | -2.97e-02 | 9.09e-02 | 5.84e-02 | 4.71e-01 | 1.15e-01 | 7.61e-01 |
| NUCLEAR IMPORT OF REV PROTEIN | 32 | 1.61e-01 | 2.50e-01 | 0.3010 | 0.117000 | -0.189000 | 0.090500 | -1.07e-01 | 1.47e-01 | 2.51e-01 | 6.41e-02 | 3.75e-01 | 2.95e-01 | 1.50e-01 |
| P75NTR SIGNALS VIA NF KB | 15 | 5.69e-01 | 6.45e-01 | 0.3010 | -0.062300 | 0.027100 | -0.129000 | 1.49e-01 | -2.18e-01 | 6.76e-01 | 8.56e-01 | 3.88e-01 | 3.18e-01 | 1.44e-01 |
| PROCESSING OF INTRONLESS PRE MRNAS | 19 | 2.99e-01 | 3.95e-01 | 0.3010 | 0.018600 | -0.132000 | 0.224000 | -6.47e-02 | -1.36e-01 | 8.88e-01 | 3.18e-01 | 9.15e-02 | 6.25e-01 | 3.03e-01 |
| PRE NOTCH PROCESSING IN GOLGI | 17 | 5.47e-01 | 6.28e-01 | 0.3010 | 0.081800 | 0.085500 | 0.041900 | -5.33e-02 | 2.68e-01 | 5.59e-01 | 5.42e-01 | 7.65e-01 | 7.04e-01 | 5.55e-02 |
| SUMOYLATION OF UBIQUITINYLATION PROTEINS | 37 | 1.04e-01 | 1.82e-01 | 0.3000 | 0.079000 | -0.189000 | 0.092200 | -1.36e-01 | 1.46e-01 | 4.06e-01 | 4.66e-02 | 3.32e-01 | 1.53e-01 | 1.26e-01 |
| PARASITE INFECTION | 54 | 1.48e-02 | 3.96e-02 | 0.3000 | 0.042200 | -0.141000 | 0.096900 | -1.44e-01 | 1.96e-01 | 5.92e-01 | 7.40e-02 | 2.18e-01 | 6.67e-02 | 1.29e-02 |
| NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | 16 | 5.96e-01 | 6.66e-01 | 0.3000 | -0.143000 | 0.053000 | -0.047300 | 2.33e-01 | -1.01e-01 | 3.20e-01 | 7.14e-01 | 7.43e-01 | 1.07e-01 | 4.84e-01 |
| SIGNALING BY ERBB4 | 56 | 6.65e-02 | 1.28e-01 | 0.3000 | -0.150000 | -0.045400 | -0.208000 | -1.15e-01 | -9.45e-02 | 5.25e-02 | 5.57e-01 | 7.05e-03 | 1.38e-01 | 2.22e-01 |
| BILE ACID AND BILE SALT METABOLISM | 25 | 2.49e-01 | 3.47e-01 | 0.3000 | 0.120000 | 0.127000 | -0.082700 | -4.29e-02 | 2.25e-01 | 2.97e-01 | 2.71e-01 | 4.74e-01 | 7.11e-01 | 5.20e-02 |
| ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS | 19 | 3.00e-01 | 3.95e-01 | 0.3000 | -0.239000 | 0.131000 | 0.075200 | 9.76e-02 | -2.17e-02 | 7.14e-02 | 3.25e-01 | 5.71e-01 | 4.62e-01 | 8.70e-01 |
| SLC TRANSPORTER DISORDERS | 64 | 1.49e-02 | 3.98e-02 | 0.3000 | 0.180000 | -0.091500 | 0.038300 | -9.39e-02 | 1.97e-01 | 1.30e-02 | 2.06e-01 | 5.96e-01 | 1.94e-01 | 6.46e-03 |
| ARACHIDONIC ACID METABOLISM | 37 | 6.75e-02 | 1.30e-01 | 0.2990 | 0.059400 | 0.140000 | -0.087100 | 2.36e-01 | 5.53e-02 | 5.32e-01 | 1.40e-01 | 3.60e-01 | 1.31e-02 | 5.61e-01 |
| POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE | 25 | 2.69e-01 | 3.68e-01 | 0.2990 | 0.047500 | 0.060100 | 0.079300 | 2.54e-01 | -1.11e-01 | 6.81e-01 | 6.03e-01 | 4.93e-01 | 2.77e-02 | 3.36e-01 |
| TCR SIGNALING | 98 | 3.55e-04 | 1.80e-03 | 0.2980 | -0.162000 | 0.009010 | -0.053800 | 2.21e-01 | -1.05e-01 | 5.52e-03 | 8.78e-01 | 3.58e-01 | 1.61e-04 | 7.33e-02 |
| DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE | 41 | 6.10e-02 | 1.21e-01 | 0.2980 | -0.100000 | 0.157000 | -0.201000 | 1.09e-01 | -4.44e-02 | 2.66e-01 | 8.20e-02 | 2.60e-02 | 2.28e-01 | 6.23e-01 |
| APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | 32 | 6.04e-02 | 1.20e-01 | 0.2970 | -0.097100 | 0.047300 | -0.073200 | -2.24e-01 | 1.45e-01 | 3.42e-01 | 6.43e-01 | 4.74e-01 | 2.81e-02 | 1.56e-01 |
| CARDIAC CONDUCTION | 102 | 1.48e-03 | 5.99e-03 | 0.2970 | 0.180000 | -0.022800 | 0.125000 | -1.26e-01 | 1.53e-01 | 1.69e-03 | 6.90e-01 | 2.90e-02 | 2.85e-02 | 7.46e-03 |
| RHOD GTPASE CYCLE | 49 | 1.77e-02 | 4.53e-02 | 0.2970 | 0.070800 | -0.020400 | 0.061500 | -2.77e-01 | 4.37e-02 | 3.91e-01 | 8.05e-01 | 4.57e-01 | 7.94e-04 | 5.97e-01 |
| SIGNALING BY THE B CELL RECEPTOR BCR | 103 | 1.08e-05 | 7.85e-05 | 0.2960 | -0.190000 | -0.088200 | -0.026600 | 2.06e-01 | -2.78e-02 | 8.89e-04 | 1.22e-01 | 6.41e-01 | 3.09e-04 | 6.27e-01 |
| TRANSCRIPTIONAL REGULATION BY E2F6 | 34 | 2.64e-01 | 3.62e-01 | 0.2950 | -0.128000 | -0.219000 | -0.079700 | -1.27e-01 | -2.33e-02 | 1.96e-01 | 2.75e-02 | 4.21e-01 | 2.01e-01 | 8.14e-01 |
| TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS | 58 | 5.66e-03 | 1.84e-02 | 0.2950 | 0.201000 | 0.135000 | -0.046000 | -1.22e-01 | 1.05e-01 | 8.00e-03 | 7.44e-02 | 5.45e-01 | 1.09e-01 | 1.66e-01 |
| ESTROGEN DEPENDENT GENE EXPRESSION | 99 | 5.85e-03 | 1.89e-02 | 0.2950 | -0.156000 | -0.079100 | -0.140000 | -1.02e-01 | -1.62e-01 | 7.41e-03 | 1.74e-01 | 1.59e-02 | 7.90e-02 | 5.50e-03 |
| SLC MEDIATED TRANSMEMBRANE TRANSPORT | 172 | 8.51e-07 | 8.24e-06 | 0.2950 | 0.165000 | 0.042000 | 0.014300 | -1.26e-01 | 2.05e-01 | 1.98e-04 | 3.43e-01 | 7.47e-01 | 4.53e-03 | 3.72e-06 |
| FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES | 15 | 5.55e-01 | 6.35e-01 | 0.2940 | 0.087400 | -0.144000 | -0.037300 | -7.41e-02 | 2.26e-01 | 5.58e-01 | 3.33e-01 | 8.03e-01 | 6.19e-01 | 1.29e-01 |
| FANCONI ANEMIA PATHWAY | 36 | 1.84e-01 | 2.74e-01 | 0.2940 | 0.180000 | 0.157000 | 0.057400 | 1.59e-01 | 2.78e-02 | 6.18e-02 | 1.03e-01 | 5.51e-01 | 9.84e-02 | 7.73e-01 |
| DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 | 24 | 4.03e-01 | 5.01e-01 | 0.2940 | 0.046100 | -0.201000 | -0.140000 | -1.52e-01 | 3.34e-02 | 6.96e-01 | 8.81e-02 | 2.35e-01 | 1.99e-01 | 7.77e-01 |
| CYTOSOLIC SULFONATION OF SMALL MOLECULES | 15 | 6.98e-01 | 7.47e-01 | 0.2930 | 0.004630 | 0.144000 | 0.204000 | 1.38e-01 | 6.62e-02 | 9.75e-01 | 3.35e-01 | 1.72e-01 | 3.53e-01 | 6.57e-01 |
| DEFECTS IN VITAMIN AND COFACTOR METABOLISM | 20 | 4.36e-01 | 5.28e-01 | 0.2920 | 0.030600 | 0.199000 | -0.088100 | 1.41e-01 | 1.32e-01 | 8.13e-01 | 1.24e-01 | 4.95e-01 | 2.75e-01 | 3.08e-01 |
| LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS | 19 | 4.40e-01 | 5.29e-01 | 0.2920 | -0.165000 | -0.142000 | 0.040000 | -1.65e-01 | -9.68e-02 | 2.13e-01 | 2.83e-01 | 7.63e-01 | 2.14e-01 | 4.65e-01 |
| SPHINGOLIPID METABOLISM | 78 | 2.68e-04 | 1.40e-03 | 0.2920 | -0.024200 | -0.011300 | -0.090500 | -8.32e-03 | 2.77e-01 | 7.12e-01 | 8.63e-01 | 1.67e-01 | 8.99e-01 | 2.44e-05 |
| PEXOPHAGY | 11 | 8.29e-01 | 8.61e-01 | 0.2920 | 0.032800 | 0.158000 | 0.103000 | 2.08e-01 | -7.48e-02 | 8.51e-01 | 3.63e-01 | 5.56e-01 | 2.33e-01 | 6.67e-01 |
| RND1 GTPASE CYCLE | 37 | 1.24e-01 | 2.07e-01 | 0.2920 | 0.042000 | -0.050800 | -0.127000 | -2.52e-01 | 3.42e-02 | 6.58e-01 | 5.93e-01 | 1.80e-01 | 8.04e-03 | 7.19e-01 |
| NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 23 | 2.85e-01 | 3.79e-01 | 0.2920 | -0.144000 | -0.005840 | 0.020700 | -1.12e-01 | -2.27e-01 | 2.31e-01 | 9.61e-01 | 8.63e-01 | 3.54e-01 | 6.00e-02 |
| INFLAMMASOMES | 19 | 4.51e-01 | 5.40e-01 | 0.2910 | -0.062200 | 0.043200 | -0.248000 | -7.66e-02 | -1.08e-01 | 6.39e-01 | 7.44e-01 | 6.17e-02 | 5.63e-01 | 4.15e-01 |
| HIV INFECTION | 218 | 1.24e-10 | 2.20e-09 | 0.2900 | -0.161000 | -0.003830 | 0.057800 | 2.23e-01 | -7.34e-02 | 4.37e-05 | 9.22e-01 | 1.42e-01 | 1.49e-08 | 6.24e-02 |
| CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | 72 | 9.02e-03 | 2.71e-02 | 0.2900 | 0.094500 | -0.050400 | 0.043900 | -1.72e-01 | 2.02e-01 | 1.66e-01 | 4.60e-01 | 5.20e-01 | 1.16e-02 | 3.05e-03 |
| ONCOGENE INDUCED SENESCENCE | 32 | 2.67e-01 | 3.65e-01 | 0.2890 | -0.032900 | -0.165000 | -0.044800 | -1.02e-01 | -2.07e-01 | 7.48e-01 | 1.07e-01 | 6.61e-01 | 3.16e-01 | 4.24e-02 |
| TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN | 12 | 7.95e-01 | 8.33e-01 | 0.2890 | 0.162000 | 0.081700 | 0.057400 | 1.53e-01 | 1.54e-01 | 3.31e-01 | 6.24e-01 | 7.31e-01 | 3.59e-01 | 3.55e-01 |
| BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA | 16 | 4.21e-01 | 5.17e-01 | 0.2890 | -0.154000 | 0.037200 | 0.171000 | 1.64e-01 | 4.51e-02 | 2.88e-01 | 7.97e-01 | 2.35e-01 | 2.56e-01 | 7.55e-01 |
| SYNTHESIS OF BILE ACIDS AND BILE SALTS | 22 | 4.79e-01 | 5.66e-01 | 0.2870 | 0.121000 | 0.097400 | 0.002570 | -1.28e-02 | 2.41e-01 | 3.28e-01 | 4.29e-01 | 9.83e-01 | 9.17e-01 | 5.02e-02 |
| DEPOLYMERISATION OF THE NUCLEAR LAMINA | 13 | 8.13e-01 | 8.47e-01 | 0.2860 | 0.194000 | -0.009890 | 0.133000 | -9.06e-02 | 1.36e-01 | 2.26e-01 | 9.51e-01 | 4.08e-01 | 5.72e-01 | 3.97e-01 |
| GLUTATHIONE SYNTHESIS AND RECYCLING | 11 | 8.03e-01 | 8.39e-01 | 0.2860 | -0.015800 | 0.146000 | -0.011100 | 2.22e-01 | 1.04e-01 | 9.28e-01 | 4.01e-01 | 9.49e-01 | 2.02e-01 | 5.50e-01 |
| COLLAGEN CHAIN TRIMERIZATION | 36 | 6.04e-02 | 1.20e-01 | 0.2860 | -0.000401 | -0.031000 | 0.042100 | -2.29e-01 | -1.63e-01 | 9.97e-01 | 7.47e-01 | 6.62e-01 | 1.74e-02 | 8.98e-02 |
| SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | 31 | 3.53e-01 | 4.50e-01 | 0.2860 | -0.141000 | -0.108000 | -0.062400 | -1.50e-01 | -1.54e-01 | 1.73e-01 | 2.96e-01 | 5.48e-01 | 1.49e-01 | 1.38e-01 |
| RAC2 GTPASE CYCLE | 86 | 8.88e-04 | 3.95e-03 | 0.2850 | 0.061800 | 0.016900 | -0.087500 | -2.00e-01 | 1.72e-01 | 3.22e-01 | 7.87e-01 | 1.61e-01 | 1.34e-03 | 5.81e-03 |
| REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS | 12 | 6.47e-01 | 7.07e-01 | 0.2850 | 0.124000 | -0.219000 | 0.033900 | -1.99e-02 | 1.29e-01 | 4.58e-01 | 1.89e-01 | 8.39e-01 | 9.05e-01 | 4.39e-01 |
| KERATAN SULFATE BIOSYNTHESIS | 24 | 4.94e-01 | 5.81e-01 | 0.2850 | 0.056600 | 0.152000 | 0.071000 | 8.73e-02 | 2.06e-01 | 6.32e-01 | 1.97e-01 | 5.47e-01 | 4.59e-01 | 8.08e-02 |
| BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS | 11 | 6.14e-01 | 6.80e-01 | 0.2850 | 0.054200 | -0.000370 | -0.063000 | 2.66e-01 | -5.95e-02 | 7.56e-01 | 9.98e-01 | 7.18e-01 | 1.26e-01 | 7.32e-01 |
| SPHINGOLIPID DE NOVO BIOSYNTHESIS | 41 | 5.15e-02 | 1.06e-01 | 0.2850 | -0.058300 | -0.066700 | -0.202000 | -3.97e-02 | 1.75e-01 | 5.19e-01 | 4.60e-01 | 2.52e-02 | 6.60e-01 | 5.19e-02 |
| CLASS B 2 SECRETIN FAMILY RECEPTORS | 63 | 5.73e-03 | 1.85e-02 | 0.2840 | -0.242000 | 0.107000 | -0.004110 | 2.23e-02 | -1.02e-01 | 9.07e-04 | 1.44e-01 | 9.55e-01 | 7.60e-01 | 1.63e-01 |
| PHOSPHOLIPID METABOLISM | 184 | 2.78e-07 | 3.00e-06 | 0.2840 | 0.132000 | -0.107000 | 0.032900 | -7.96e-02 | 2.10e-01 | 1.99e-03 | 1.21e-02 | 4.42e-01 | 6.30e-02 | 9.62e-07 |
| GLUCOSE METABOLISM | 79 | 2.23e-03 | 8.69e-03 | 0.2830 | 0.028200 | 0.008260 | 0.174000 | 4.29e-02 | 2.17e-01 | 6.65e-01 | 8.99e-01 | 7.45e-03 | 5.10e-01 | 8.37e-04 |
| LAMININ INTERACTIONS | 27 | 1.92e-01 | 2.82e-01 | 0.2830 | 0.088300 | 0.019200 | -0.105000 | -2.47e-01 | -3.90e-03 | 4.27e-01 | 8.63e-01 | 3.44e-01 | 2.64e-02 | 9.72e-01 |
| NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX | 32 | 1.60e-01 | 2.50e-01 | 0.2830 | 0.182000 | -0.052600 | -0.071600 | -1.97e-01 | 1.93e-02 | 7.55e-02 | 6.07e-01 | 4.84e-01 | 5.35e-02 | 8.50e-01 |
| TP53 REGULATES METABOLIC GENES | 85 | 8.50e-04 | 3.81e-03 | 0.2830 | -0.171000 | -0.022100 | -0.033700 | 2.19e-01 | -3.48e-02 | 6.50e-03 | 7.25e-01 | 5.91e-01 | 4.79e-04 | 5.79e-01 |
| NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 48 | 1.21e-01 | 2.05e-01 | 0.2830 | -0.052300 | -0.143000 | -0.042100 | -2.16e-01 | -9.13e-02 | 5.31e-01 | 8.62e-02 | 6.14e-01 | 9.74e-03 | 2.74e-01 |
| PROCESSING AND ACTIVATION OF SUMO | 10 | 8.21e-01 | 8.54e-01 | 0.2830 | -0.116000 | 0.097200 | 0.025600 | 2.35e-01 | 3.48e-02 | 5.26e-01 | 5.94e-01 | 8.89e-01 | 1.99e-01 | 8.49e-01 |
| TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA | 16 | 4.71e-01 | 5.58e-01 | 0.2820 | -0.136000 | 0.017300 | 0.123000 | 2.05e-01 | 6.29e-02 | 3.47e-01 | 9.05e-01 | 3.94e-01 | 1.56e-01 | 6.63e-01 |
| SIGNALING BY NTRKS | 126 | 1.34e-04 | 7.50e-04 | 0.2820 | 0.096600 | -0.131000 | 0.098300 | -1.67e-01 | 1.25e-01 | 6.15e-02 | 1.13e-02 | 5.70e-02 | 1.26e-03 | 1.54e-02 |
| CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER | 56 | 2.40e-02 | 5.79e-02 | 0.2820 | 0.118000 | -0.037200 | -0.128000 | -1.81e-01 | 1.22e-01 | 1.27e-01 | 6.30e-01 | 9.68e-02 | 1.91e-02 | 1.15e-01 |
| TOLL LIKE RECEPTOR 9 TLR9 CASCADE | 89 | 3.38e-03 | 1.20e-02 | 0.2810 | 0.137000 | -0.124000 | -0.011400 | -1.41e-01 | 1.59e-01 | 2.61e-02 | 4.38e-02 | 8.52e-01 | 2.18e-02 | 9.54e-03 |
| POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 60 | 3.34e-02 | 7.56e-02 | 0.2810 | -0.120000 | -0.015800 | -0.010100 | 1.53e-01 | -2.02e-01 | 1.08e-01 | 8.32e-01 | 8.93e-01 | 4.09e-02 | 6.72e-03 |
| FATTY ACYL COA BIOSYNTHESIS | 32 | 1.42e-01 | 2.28e-01 | 0.2810 | -0.011800 | 0.106000 | -0.084600 | 1.52e-02 | 2.45e-01 | 9.08e-01 | 2.98e-01 | 4.08e-01 | 8.81e-01 | 1.65e-02 |
| SEPARATION OF SISTER CHROMATIDS | 165 | 3.73e-08 | 4.52e-07 | 0.2800 | -0.191000 | -0.024900 | 0.018200 | 2.03e-01 | -1.13e-02 | 2.39e-05 | 5.82e-01 | 6.87e-01 | 7.34e-06 | 8.02e-01 |
| SELECTIVE AUTOPHAGY | 71 | 2.25e-03 | 8.69e-03 | 0.2790 | -0.060200 | -0.025500 | 0.086500 | 2.56e-01 | -2.22e-02 | 3.81e-01 | 7.10e-01 | 2.08e-01 | 1.92e-04 | 7.46e-01 |
| PROLACTIN RECEPTOR SIGNALING | 11 | 6.53e-01 | 7.10e-01 | 0.2790 | -0.030700 | 0.116000 | -0.031900 | -1.82e-01 | 1.71e-01 | 8.60e-01 | 5.06e-01 | 8.55e-01 | 2.96e-01 | 3.26e-01 |
| INTRAFLAGELLAR TRANSPORT | 49 | 2.49e-02 | 5.94e-02 | 0.2780 | -0.127000 | 0.168000 | 0.152000 | 8.60e-02 | -4.73e-02 | 1.23e-01 | 4.16e-02 | 6.49e-02 | 2.98e-01 | 5.67e-01 |
| PI 3K CASCADE FGFR1 | 14 | 6.43e-01 | 7.03e-01 | 0.2780 | 0.199000 | -0.102000 | -0.059500 | -7.65e-02 | 1.35e-01 | 1.98e-01 | 5.08e-01 | 7.00e-01 | 6.20e-01 | 3.83e-01 |
| C TYPE LECTIN RECEPTORS CLRS | 110 | 5.00e-05 | 3.08e-04 | 0.2780 | -0.171000 | -0.042200 | -0.079900 | 1.99e-01 | -3.39e-03 | 1.91e-03 | 4.44e-01 | 1.48e-01 | 3.08e-04 | 9.51e-01 |
| O LINKED GLYCOSYLATION OF MUCINS | 40 | 9.00e-02 | 1.63e-01 | 0.2780 | 0.025300 | 0.067800 | 0.047800 | -1.10e-01 | 2.40e-01 | 7.82e-01 | 4.58e-01 | 6.01e-01 | 2.30e-01 | 8.65e-03 |
| CD28 CO STIMULATION | 30 | 2.09e-01 | 3.02e-01 | 0.2780 | 0.022200 | -0.198000 | 0.004880 | -9.27e-02 | 1.69e-01 | 8.33e-01 | 6.04e-02 | 9.63e-01 | 3.80e-01 | 1.08e-01 |
| NEGATIVE REGULATION OF MAPK PATHWAY | 41 | 2.01e-02 | 5.04e-02 | 0.2780 | -0.048900 | -0.199000 | 0.120000 | 1.08e-02 | 1.43e-01 | 5.88e-01 | 2.73e-02 | 1.82e-01 | 9.05e-01 | 1.14e-01 |
| METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION | 15 | 6.06e-01 | 6.74e-01 | 0.2770 | -0.113000 | 0.078300 | -0.224000 | 5.05e-02 | 7.28e-02 | 4.49e-01 | 6.00e-01 | 1.33e-01 | 7.35e-01 | 6.26e-01 |
| PECAM1 INTERACTIONS | 12 | 7.90e-01 | 8.30e-01 | 0.2770 | 0.109000 | -0.084000 | -0.027000 | -2.37e-01 | 3.14e-02 | 5.13e-01 | 6.15e-01 | 8.71e-01 | 1.55e-01 | 8.50e-01 |
| RIPK1 MEDIATED REGULATED NECROSIS | 25 | 5.32e-01 | 6.14e-01 | 0.2770 | -0.175000 | -0.020900 | -0.172000 | 7.58e-02 | -1.02e-01 | 1.29e-01 | 8.57e-01 | 1.37e-01 | 5.12e-01 | 3.79e-01 |
| SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS | 55 | 4.47e-02 | 9.48e-02 | 0.2770 | 0.067700 | -0.218000 | 0.075700 | -1.34e-01 | 2.97e-02 | 3.86e-01 | 5.17e-03 | 3.32e-01 | 8.66e-02 | 7.03e-01 |
| RHOJ GTPASE CYCLE | 54 | 5.19e-02 | 1.07e-01 | 0.2760 | 0.112000 | -0.060300 | -0.076500 | -2.15e-01 | 9.05e-02 | 1.56e-01 | 4.44e-01 | 3.31e-01 | 6.26e-03 | 2.50e-01 |
| PLATELET AGGREGATION PLUG FORMATION | 31 | 2.33e-01 | 3.29e-01 | 0.2760 | 0.005310 | -0.059400 | -0.021000 | -1.96e-01 | 1.84e-01 | 9.59e-01 | 5.67e-01 | 8.40e-01 | 5.91e-02 | 7.67e-02 |
| GAP JUNCTION TRAFFICKING AND REGULATION | 32 | 2.79e-01 | 3.75e-01 | 0.2760 | -0.084900 | 0.210000 | 0.054700 | 1.40e-01 | 4.65e-02 | 4.06e-01 | 4.00e-02 | 5.92e-01 | 1.71e-01 | 6.49e-01 |
| SYNTHESIS OF PA | 28 | 2.99e-01 | 3.95e-01 | 0.2760 | -0.054900 | -0.176000 | -0.031300 | -1.49e-01 | 1.36e-01 | 6.15e-01 | 1.07e-01 | 7.75e-01 | 1.71e-01 | 2.12e-01 |
| MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | 15 | 5.88e-01 | 6.61e-01 | 0.2750 | 0.119000 | 0.081800 | 0.047800 | 1.79e-01 | -1.44e-01 | 4.25e-01 | 5.83e-01 | 7.49e-01 | 2.31e-01 | 3.34e-01 |
| ER TO GOLGI ANTEROGRADE TRANSPORT | 138 | 1.55e-05 | 1.09e-04 | 0.2750 | 0.024200 | 0.019500 | 0.165000 | 9.48e-02 | 1.96e-01 | 6.23e-01 | 6.93e-01 | 8.28e-04 | 5.48e-02 | 7.02e-05 |
| SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | 18 | 3.26e-01 | 4.24e-01 | 0.2750 | 0.109000 | -0.208000 | 0.075000 | 1.03e-01 | -6.63e-02 | 4.24e-01 | 1.27e-01 | 5.82e-01 | 4.50e-01 | 6.26e-01 |
| FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS | 81 | 6.95e-03 | 2.17e-02 | 0.2750 | 0.076800 | -0.141000 | 0.067100 | -1.41e-01 | 1.59e-01 | 2.33e-01 | 2.85e-02 | 2.96e-01 | 2.84e-02 | 1.33e-02 |
| ACTIVATION OF THE PRE REPLICATIVE COMPLEX | 28 | 2.75e-01 | 3.73e-01 | 0.2750 | -0.009110 | 0.089700 | -0.013700 | 1.97e-01 | 1.68e-01 | 9.33e-01 | 4.11e-01 | 9.00e-01 | 7.09e-02 | 1.24e-01 |
| CARNITINE METABOLISM | 14 | 6.58e-01 | 7.13e-01 | 0.2740 | 0.140000 | 0.114000 | -0.093900 | -4.03e-04 | 1.84e-01 | 3.64e-01 | 4.62e-01 | 5.43e-01 | 9.98e-01 | 2.33e-01 |
| SIGNAL TRANSDUCTION BY L1 | 21 | 3.85e-01 | 4.82e-01 | 0.2740 | 0.011300 | -0.093400 | 0.141000 | -2.16e-01 | 8.32e-03 | 9.29e-01 | 4.59e-01 | 2.64e-01 | 8.71e-02 | 9.47e-01 |
| INTERLEUKIN 15 SIGNALING | 13 | 6.34e-01 | 6.95e-01 | 0.2740 | 0.059400 | 0.049500 | -0.006000 | -2.54e-01 | 6.83e-02 | 7.11e-01 | 7.57e-01 | 9.70e-01 | 1.13e-01 | 6.70e-01 |
| CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN | 34 | 2.37e-01 | 3.35e-01 | 0.2730 | -0.045800 | 0.162000 | 0.110000 | 1.16e-01 | 1.44e-01 | 6.44e-01 | 1.03e-01 | 2.68e-01 | 2.41e-01 | 1.46e-01 |
| TBC RABGAPS | 41 | 7.75e-02 | 1.45e-01 | 0.2720 | 0.015000 | -0.037100 | 0.161000 | -1.76e-02 | 2.15e-01 | 8.68e-01 | 6.81e-01 | 7.47e-02 | 8.46e-01 | 1.71e-02 |
| NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | 40 | 1.78e-01 | 2.69e-01 | 0.2720 | -0.000768 | -0.100000 | -0.032200 | -2.41e-01 | 6.96e-02 | 9.93e-01 | 2.73e-01 | 7.25e-01 | 8.32e-03 | 4.47e-01 |
| SUMOYLATION OF TRANSCRIPTION COFACTORS | 42 | 1.32e-01 | 2.15e-01 | 0.2710 | -0.029400 | -0.144000 | 0.049900 | -2.02e-01 | -9.22e-02 | 7.41e-01 | 1.06e-01 | 5.76e-01 | 2.32e-02 | 3.02e-01 |
| COLLAGEN DEGRADATION | 47 | 8.34e-03 | 2.52e-02 | 0.2710 | 0.008080 | 0.099700 | -0.015700 | -2.02e-01 | -1.50e-01 | 9.24e-01 | 2.37e-01 | 8.52e-01 | 1.67e-02 | 7.47e-02 |
| TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 | 15 | 5.59e-01 | 6.38e-01 | 0.2710 | -0.174000 | -0.023100 | -0.129000 | -8.99e-03 | 1.61e-01 | 2.43e-01 | 8.77e-01 | 3.86e-01 | 9.52e-01 | 2.80e-01 |
| GRB2 EVENTS IN ERBB2 SIGNALING | 14 | 7.63e-01 | 8.08e-01 | 0.2710 | -0.091900 | -0.039400 | -0.200000 | -1.47e-01 | 4.21e-02 | 5.52e-01 | 7.98e-01 | 1.95e-01 | 3.41e-01 | 7.85e-01 |
| HDACS DEACETYLATE HISTONES | 44 | 1.81e-01 | 2.72e-01 | 0.2710 | -0.094500 | -0.075600 | -0.127000 | 5.73e-02 | -1.99e-01 | 2.78e-01 | 3.86e-01 | 1.47e-01 | 5.11e-01 | 2.28e-02 |
| TELOMERE C STRAND SYNTHESIS INITIATION | 13 | 6.39e-01 | 7.00e-01 | 0.2700 | 0.138000 | 0.021200 | 0.028200 | 2.29e-01 | -2.01e-02 | 3.90e-01 | 8.95e-01 | 8.60e-01 | 1.53e-01 | 9.00e-01 |
| PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | 12 | 6.30e-01 | 6.94e-01 | 0.2690 | -0.131000 | 0.027800 | -0.015200 | 9.97e-02 | 2.11e-01 | 4.33e-01 | 8.68e-01 | 9.28e-01 | 5.50e-01 | 2.06e-01 |
| INWARDLY RECTIFYING K CHANNELS | 31 | 7.02e-02 | 1.34e-01 | 0.2690 | -0.187000 | -0.152000 | 0.104000 | 1.56e-03 | 6.00e-02 | 7.21e-02 | 1.43e-01 | 3.15e-01 | 9.88e-01 | 5.63e-01 |
| SHC MEDIATED CASCADE FGFR1 | 14 | 5.24e-01 | 6.07e-01 | 0.2690 | 0.064800 | -0.117000 | -0.096100 | 5.95e-02 | 2.04e-01 | 6.75e-01 | 4.50e-01 | 5.34e-01 | 7.00e-01 | 1.86e-01 |
| UPTAKE AND ACTIONS OF BACTERIAL TOXINS | 27 | 2.52e-01 | 3.51e-01 | 0.2690 | 0.115000 | -0.194000 | -0.008460 | -2.96e-02 | 1.42e-01 | 3.00e-01 | 8.09e-02 | 9.39e-01 | 7.90e-01 | 2.01e-01 |
| NOD1 2 SIGNALING PATHWAY | 34 | 5.31e-02 | 1.08e-01 | 0.2690 | 0.131000 | -0.194000 | -0.124000 | 2.68e-02 | 2.99e-02 | 1.86e-01 | 4.98e-02 | 2.09e-01 | 7.87e-01 | 7.63e-01 |
| GAP JUNCTION DEGRADATION | 11 | 6.67e-01 | 7.20e-01 | 0.2680 | -0.053700 | 0.187000 | 0.081300 | -8.17e-02 | 1.44e-01 | 7.58e-01 | 2.82e-01 | 6.41e-01 | 6.39e-01 | 4.08e-01 |
| AUTOPHAGY | 137 | 4.61e-06 | 3.69e-05 | 0.2680 | -0.024200 | -0.000777 | 0.112000 | 2.26e-01 | 8.78e-02 | 6.25e-01 | 9.87e-01 | 2.37e-02 | 4.94e-06 | 7.64e-02 |
| RMTS METHYLATE HISTONE ARGININES | 42 | 1.08e-01 | 1.88e-01 | 0.2680 | -0.111000 | -0.088400 | -0.031200 | 1.75e-01 | -1.42e-01 | 2.15e-01 | 3.22e-01 | 7.26e-01 | 4.95e-02 | 1.10e-01 |
| CELL CELL COMMUNICATION | 101 | 8.15e-04 | 3.71e-03 | 0.2680 | -0.022100 | -0.053800 | -0.041500 | -2.41e-01 | 9.22e-02 | 7.01e-01 | 3.51e-01 | 4.72e-01 | 2.84e-05 | 1.10e-01 |
| PROCESSING OF DNA DOUBLE STRAND BREAK ENDS | 67 | 7.00e-02 | 1.34e-01 | 0.2680 | -0.168000 | -0.049800 | -0.116000 | 8.76e-02 | -1.40e-01 | 1.73e-02 | 4.81e-01 | 9.98e-02 | 2.15e-01 | 4.74e-02 |
| GPVI MEDIATED ACTIVATION CASCADE | 31 | 1.61e-01 | 2.50e-01 | 0.2680 | -0.060400 | -0.030600 | -0.139000 | -1.84e-02 | 2.18e-01 | 5.61e-01 | 7.68e-01 | 1.81e-01 | 8.59e-01 | 3.58e-02 |
| ACYL CHAIN REMODELLING OF PS | 14 | 6.24e-01 | 6.90e-01 | 0.2670 | 0.059700 | -0.027400 | 0.234000 | -7.27e-02 | -8.52e-02 | 6.99e-01 | 8.59e-01 | 1.30e-01 | 6.38e-01 | 5.81e-01 |
| TRANSCRIPTIONAL REGULATION BY RUNX3 | 93 | 7.96e-03 | 2.43e-02 | 0.2670 | -0.185000 | 0.023100 | -0.059200 | 1.46e-01 | -1.09e-01 | 2.10e-03 | 7.00e-01 | 3.24e-01 | 1.53e-02 | 7.03e-02 |
| REGULATION OF IFNG SIGNALING | 13 | 4.59e-01 | 5.46e-01 | 0.2670 | 0.100000 | -0.086100 | -0.167000 | 1.37e-01 | 8.36e-02 | 5.31e-01 | 5.91e-01 | 2.96e-01 | 3.94e-01 | 6.02e-01 |
| COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 44 | 1.52e-02 | 4.05e-02 | 0.2670 | -0.138000 | -0.024300 | 0.109000 | 8.51e-02 | 1.80e-01 | 1.13e-01 | 7.80e-01 | 2.12e-01 | 3.29e-01 | 3.93e-02 |
| PROCESSIVE SYNTHESIS ON THE LAGGING STRAND | 15 | 5.90e-01 | 6.62e-01 | 0.2660 | -0.064700 | 0.039400 | -0.153000 | 1.97e-01 | 5.64e-02 | 6.64e-01 | 7.92e-01 | 3.05e-01 | 1.87e-01 | 7.05e-01 |
| RHO GTPASES ACTIVATE CIT | 18 | 3.79e-01 | 4.76e-01 | 0.2660 | 0.120000 | 0.054700 | 0.007380 | 1.57e-02 | -2.30e-01 | 3.78e-01 | 6.88e-01 | 9.57e-01 | 9.08e-01 | 9.10e-02 |
| HEDGEHOG OFF STATE | 106 | 2.04e-04 | 1.10e-03 | 0.2660 | -0.236000 | -0.030800 | 0.025600 | 9.84e-02 | -5.74e-02 | 2.62e-05 | 5.84e-01 | 6.49e-01 | 8.03e-02 | 3.08e-01 |
| SIGNALING BY TGF BETA RECEPTOR COMPLEX | 72 | 3.53e-02 | 7.88e-02 | 0.2650 | -0.146000 | -0.132000 | -0.065700 | -1.64e-01 | -1.15e-02 | 3.19e-02 | 5.26e-02 | 3.36e-01 | 1.61e-02 | 8.67e-01 |
| NGF STIMULATED TRANSCRIPTION | 36 | 2.61e-01 | 3.59e-01 | 0.2650 | 0.092200 | -0.138000 | 0.011300 | -2.00e-01 | -5.00e-02 | 3.38e-01 | 1.52e-01 | 9.07e-01 | 3.83e-02 | 6.04e-01 |
| G PROTEIN BETA GAMMA SIGNALLING | 30 | 1.29e-01 | 2.12e-01 | 0.2640 | -0.130000 | -0.163000 | 0.005310 | 1.62e-01 | -9.60e-03 | 2.18e-01 | 1.22e-01 | 9.60e-01 | 1.24e-01 | 9.28e-01 |
| RNA POLYMERASE I TRANSCRIPTION INITIATION | 47 | 6.03e-02 | 1.20e-01 | 0.2640 | -0.054800 | -0.019900 | 0.167000 | 1.34e-01 | -1.43e-01 | 5.16e-01 | 8.13e-01 | 4.72e-02 | 1.11e-01 | 9.06e-02 |
| SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA | 39 | 8.38e-02 | 1.55e-01 | 0.2640 | 0.097600 | 0.157000 | -0.020700 | -1.55e-01 | 1.06e-01 | 2.92e-01 | 9.06e-02 | 8.23e-01 | 9.40e-02 | 2.53e-01 |
| TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | 79 | 2.88e-03 | 1.07e-02 | 0.2640 | -0.097200 | -0.115000 | 0.120000 | 3.65e-02 | -1.77e-01 | 1.36e-01 | 7.86e-02 | 6.48e-02 | 5.76e-01 | 6.64e-03 |
| SIGNALING BY SCF KIT | 41 | 2.38e-01 | 3.35e-01 | 0.2630 | 0.003780 | -0.177000 | -0.101000 | -1.45e-01 | 7.93e-02 | 9.67e-01 | 4.95e-02 | 2.65e-01 | 1.08e-01 | 3.80e-01 |
| ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA | 15 | 6.58e-01 | 7.13e-01 | 0.2620 | -0.112000 | 0.048500 | 0.077700 | 2.11e-01 | 5.65e-02 | 4.51e-01 | 7.45e-01 | 6.02e-01 | 1.57e-01 | 7.05e-01 |
| AQUAPORIN MEDIATED TRANSPORT | 37 | 1.34e-01 | 2.18e-01 | 0.2610 | -0.137000 | -0.163000 | 0.062700 | -1.37e-01 | -3.93e-03 | 1.48e-01 | 8.60e-02 | 5.09e-01 | 1.48e-01 | 9.67e-01 |
| DISEASES OF PROGRAMMED CELL DEATH | 51 | 4.71e-02 | 9.94e-02 | 0.2610 | -0.003050 | 0.101000 | -0.124000 | 1.99e-01 | -5.43e-02 | 9.70e-01 | 2.13e-01 | 1.25e-01 | 1.40e-02 | 5.02e-01 |
| GROWTH HORMONE RECEPTOR SIGNALING | 20 | 6.43e-01 | 7.03e-01 | 0.2600 | 0.086700 | -0.121000 | -0.039900 | -2.09e-01 | -1.30e-02 | 5.02e-01 | 3.49e-01 | 7.57e-01 | 1.05e-01 | 9.20e-01 |
| SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | 62 | 6.51e-02 | 1.27e-01 | 0.2600 | 0.062800 | 0.029800 | 0.148000 | 1.25e-01 | 1.59e-01 | 3.92e-01 | 6.85e-01 | 4.46e-02 | 8.92e-02 | 3.06e-02 |
| DOWNREGULATION OF ERBB2 SIGNALING | 27 | 6.24e-01 | 6.90e-01 | 0.2600 | -0.140000 | -0.093300 | -0.143000 | 9.83e-03 | -1.36e-01 | 2.07e-01 | 4.01e-01 | 1.99e-01 | 9.30e-01 | 2.21e-01 |
| RHO GTPASES ACTIVATE WASPS AND WAVES | 36 | 2.00e-01 | 2.93e-01 | 0.2590 | 0.064400 | -0.089300 | 0.200000 | -2.91e-02 | 1.20e-01 | 5.04e-01 | 3.54e-01 | 3.81e-02 | 7.63e-01 | 2.14e-01 |
| ELEVATION OF CYTOSOLIC CA2 LEVELS | 14 | 7.83e-01 | 8.25e-01 | 0.2590 | 0.122000 | 0.127000 | -0.023500 | -1.55e-02 | 1.87e-01 | 4.29e-01 | 4.09e-01 | 8.79e-01 | 9.20e-01 | 2.25e-01 |
| NEDDYLATION | 214 | 2.77e-09 | 4.25e-08 | 0.2590 | -0.080100 | 0.031600 | 0.101000 | 1.86e-01 | 1.21e-01 | 4.39e-02 | 4.26e-01 | 1.13e-02 | 2.73e-06 | 2.23e-03 |
| TRANSCRIPTIONAL REGULATION BY VENTX | 35 | 2.67e-01 | 3.65e-01 | 0.2580 | -0.081800 | -0.075000 | -0.023500 | -2.02e-01 | -1.14e-01 | 4.02e-01 | 4.43e-01 | 8.10e-01 | 3.84e-02 | 2.45e-01 |
| TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS | 41 | 1.67e-01 | 2.57e-01 | 0.2580 | 0.089200 | -0.125000 | 0.175000 | -6.33e-02 | 9.32e-02 | 3.23e-01 | 1.67e-01 | 5.31e-02 | 4.83e-01 | 3.02e-01 |
| MISMATCH REPAIR | 14 | 7.01e-01 | 7.49e-01 | 0.2580 | -0.208000 | 0.057100 | -0.019100 | 1.37e-01 | 3.11e-02 | 1.78e-01 | 7.12e-01 | 9.01e-01 | 3.74e-01 | 8.40e-01 |
| INTEGRATION OF ENERGY METABOLISM | 96 | 3.25e-03 | 1.17e-02 | 0.2570 | 0.053000 | -0.116000 | 0.125000 | -1.60e-01 | 9.15e-02 | 3.70e-01 | 5.05e-02 | 3.44e-02 | 6.66e-03 | 1.22e-01 |
| TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | 30 | 4.39e-01 | 5.29e-01 | 0.2570 | 0.065300 | 0.125000 | 0.010100 | 9.58e-02 | 1.91e-01 | 5.36e-01 | 2.35e-01 | 9.24e-01 | 3.64e-01 | 6.96e-02 |
| G0 AND EARLY G1 | 24 | 3.51e-01 | 4.48e-01 | 0.2560 | -0.122000 | 0.056000 | -0.137000 | 3.90e-02 | 1.66e-01 | 3.03e-01 | 6.35e-01 | 2.45e-01 | 7.41e-01 | 1.60e-01 |
| SENSORY PROCESSING OF SOUND | 59 | 7.67e-02 | 1.44e-01 | 0.2560 | 0.142000 | 0.043400 | 0.116000 | -1.45e-01 | 9.55e-02 | 5.99e-02 | 5.64e-01 | 1.24e-01 | 5.38e-02 | 2.05e-01 |
| TNFR1 INDUCED PROAPOPTOTIC SIGNALING | 12 | 8.47e-01 | 8.73e-01 | 0.2560 | 0.150000 | -0.123000 | -0.004520 | -1.24e-01 | 1.11e-01 | 3.67e-01 | 4.59e-01 | 9.78e-01 | 4.58e-01 | 5.04e-01 |
| CYCLIN D ASSOCIATED EVENTS IN G1 | 45 | 8.77e-02 | 1.60e-01 | 0.2560 | -0.228000 | 0.078100 | -0.055000 | 6.33e-02 | 2.63e-02 | 8.29e-03 | 3.65e-01 | 5.23e-01 | 4.63e-01 | 7.60e-01 |
| CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | 48 | 1.16e-01 | 1.97e-01 | 0.2560 | 0.137000 | 0.140000 | 0.119000 | -9.40e-02 | 6.14e-02 | 1.00e-01 | 9.26e-02 | 1.53e-01 | 2.60e-01 | 4.62e-01 |
| RNA POLYMERASE III TRANSCRIPTION | 41 | 1.18e-01 | 2.01e-01 | 0.2550 | 0.021000 | -0.001380 | 0.066700 | 2.45e-01 | -5.09e-03 | 8.16e-01 | 9.88e-01 | 4.60e-01 | 6.58e-03 | 9.55e-01 |
| ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION | 26 | 3.16e-01 | 4.12e-01 | 0.2540 | -0.094800 | -0.091000 | 0.120000 | -9.35e-02 | -1.55e-01 | 4.03e-01 | 4.22e-01 | 2.89e-01 | 4.09e-01 | 1.70e-01 |
| ACYL CHAIN REMODELLING OF PG | 10 | 7.46e-01 | 7.93e-01 | 0.2540 | -0.100000 | -0.117000 | 0.177000 | -9.26e-02 | -3.29e-02 | 5.84e-01 | 5.22e-01 | 3.34e-01 | 6.12e-01 | 8.57e-01 |
| ROS AND RNS PRODUCTION IN PHAGOCYTES | 29 | 2.64e-01 | 3.62e-01 | 0.2540 | -0.042000 | 0.046000 | -0.082700 | 2.16e-01 | 8.42e-02 | 6.95e-01 | 6.69e-01 | 4.41e-01 | 4.42e-02 | 4.33e-01 |
| UNFOLDED PROTEIN RESPONSE UPR | 84 | 4.42e-03 | 1.48e-02 | 0.2540 | -0.120000 | -0.222000 | -0.011500 | -2.39e-02 | 4.22e-03 | 5.78e-02 | 4.36e-04 | 8.56e-01 | 7.05e-01 | 9.47e-01 |
| DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | 13 | 8.33e-01 | 8.63e-01 | 0.2540 | -0.169000 | -0.092000 | -0.034900 | 9.77e-02 | -1.28e-01 | 2.90e-01 | 5.66e-01 | 8.27e-01 | 5.42e-01 | 4.23e-01 |
| HYALURONAN UPTAKE AND DEGRADATION | 11 | 7.79e-01 | 8.22e-01 | 0.2540 | 0.136000 | 0.164000 | 0.051600 | -1.23e-01 | 3.59e-02 | 4.35e-01 | 3.47e-01 | 7.67e-01 | 4.81e-01 | 8.37e-01 |
| COPII MEDIATED VESICLE TRANSPORT | 63 | 6.64e-02 | 1.28e-01 | 0.2530 | 0.075800 | 0.039700 | 0.063500 | 7.63e-02 | 2.17e-01 | 2.99e-01 | 5.86e-01 | 3.84e-01 | 2.95e-01 | 2.93e-03 |
| ESR MEDIATED SIGNALING | 160 | 2.07e-03 | 8.18e-03 | 0.2530 | -0.150000 | -0.113000 | -0.108000 | -9.31e-02 | -9.29e-02 | 1.11e-03 | 1.37e-02 | 1.84e-02 | 4.23e-02 | 4.29e-02 |
| PHASE I FUNCTIONALIZATION OF COMPOUNDS | 57 | 1.28e-01 | 2.11e-01 | 0.2530 | -0.011200 | 0.201000 | 0.011800 | 1.34e-01 | 7.30e-02 | 8.83e-01 | 8.67e-03 | 8.78e-01 | 7.94e-02 | 3.41e-01 |
| TCF DEPENDENT SIGNALING IN RESPONSE TO WNT | 173 | 4.58e-05 | 2.88e-04 | 0.2530 | -0.227000 | -0.039400 | -0.092100 | -2.64e-02 | -4.23e-02 | 2.69e-07 | 3.72e-01 | 3.69e-02 | 5.50e-01 | 3.37e-01 |
| CA2 PATHWAY | 55 | 1.13e-01 | 1.94e-01 | 0.2530 | 0.006530 | -0.083900 | -0.051700 | -2.29e-01 | 3.98e-02 | 9.33e-01 | 2.82e-01 | 5.07e-01 | 3.30e-03 | 6.10e-01 |
| G2 M DNA DAMAGE CHECKPOINT | 63 | 1.46e-01 | 2.32e-01 | 0.2530 | -0.169000 | -0.032600 | -0.126000 | 6.24e-02 | -1.20e-01 | 2.04e-02 | 6.55e-01 | 8.35e-02 | 3.92e-01 | 9.95e-02 |
| INTERLEUKIN 1 FAMILY SIGNALING | 118 | 1.15e-04 | 6.56e-04 | 0.2530 | -0.082300 | -0.003210 | -0.053300 | 2.33e-01 | 3.08e-03 | 1.23e-01 | 9.52e-01 | 3.18e-01 | 1.28e-05 | 9.54e-01 |
| E2F MEDIATED REGULATION OF DNA REPLICATION | 19 | 5.04e-01 | 5.92e-01 | 0.2520 | -0.196000 | -0.026700 | -0.097300 | -1.20e-02 | 1.22e-01 | 1.39e-01 | 8.40e-01 | 4.63e-01 | 9.28e-01 | 3.59e-01 |
| TRNA AMINOACYLATION | 42 | 1.04e-01 | 1.82e-01 | 0.2520 | -0.124000 | 0.063600 | 0.071600 | 1.65e-01 | 1.07e-01 | 1.63e-01 | 4.76e-01 | 4.22e-01 | 6.42e-02 | 2.30e-01 |
| RNA POLYMERASE II TRANSCRIBES SNRNA GENES | 74 | 1.25e-02 | 3.47e-02 | 0.2510 | -0.070200 | -0.159000 | 0.032700 | 7.40e-02 | -1.63e-01 | 2.97e-01 | 1.84e-02 | 6.27e-01 | 2.72e-01 | 1.54e-02 |
| ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS | 17 | 5.77e-01 | 6.52e-01 | 0.2510 | -0.231000 | 0.019400 | 0.030000 | -2.16e-02 | -8.92e-02 | 9.89e-02 | 8.90e-01 | 8.30e-01 | 8.78e-01 | 5.24e-01 |
| SIGNALING BY FGFR1 | 42 | 2.78e-01 | 3.75e-01 | 0.2510 | -0.006710 | -0.195000 | -0.006330 | -1.56e-01 | 2.80e-02 | 9.40e-01 | 2.91e-02 | 9.43e-01 | 8.05e-02 | 7.54e-01 |
| COLLAGEN FORMATION | 74 | 1.12e-02 | 3.21e-02 | 0.2510 | -0.083100 | -0.047500 | 0.012800 | -1.82e-01 | -1.43e-01 | 2.17e-01 | 4.80e-01 | 8.49e-01 | 6.89e-03 | 3.30e-02 |
| INTEGRIN CELL SURFACE INTERACTIONS | 66 | 1.08e-02 | 3.13e-02 | 0.2510 | 0.017900 | 0.033400 | -0.141000 | -1.57e-01 | -1.30e-01 | 8.01e-01 | 6.39e-01 | 4.80e-02 | 2.72e-02 | 6.87e-02 |
| FRS MEDIATED FGFR1 SIGNALING | 16 | 5.78e-01 | 6.52e-01 | 0.2510 | 0.133000 | -0.055400 | -0.076500 | 5.21e-02 | 1.83e-01 | 3.57e-01 | 7.01e-01 | 5.96e-01 | 7.18e-01 | 2.05e-01 |
| POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | 56 | 6.06e-02 | 1.20e-01 | 0.2500 | 0.132000 | 0.060600 | 0.189000 | -6.06e-02 | -4.81e-02 | 8.74e-02 | 4.33e-01 | 1.46e-02 | 4.33e-01 | 5.33e-01 |
| RHO GTPASE CYCLE | 421 | 1.27e-12 | 3.32e-11 | 0.2500 | 0.029800 | -0.083600 | -0.046500 | -2.22e-01 | 5.89e-02 | 2.97e-01 | 3.35e-03 | 1.03e-01 | 7.58e-15 | 3.90e-02 |
| MEIOSIS | 61 | 5.81e-02 | 1.16e-01 | 0.2490 | -0.113000 | 0.173000 | -0.087400 | 7.29e-02 | -8.01e-02 | 1.27e-01 | 1.94e-02 | 2.38e-01 | 3.25e-01 | 2.79e-01 |
| REGULATION OF TP53 ACTIVITY THROUGH METHYLATION | 18 | 7.88e-01 | 8.29e-01 | 0.2490 | -0.096800 | -0.087800 | -0.125000 | 2.48e-02 | -1.70e-01 | 4.77e-01 | 5.19e-01 | 3.60e-01 | 8.56e-01 | 2.12e-01 |
| EPHA MEDIATED GROWTH CONE COLLAPSE | 27 | 2.71e-01 | 3.69e-01 | 0.2490 | 0.108000 | -0.019700 | -0.014800 | -1.58e-01 | -1.58e-01 | 3.33e-01 | 8.59e-01 | 8.94e-01 | 1.57e-01 | 1.56e-01 |
| TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA | 34 | 2.81e-01 | 3.76e-01 | 0.2490 | 0.069100 | -0.166000 | 0.123000 | -7.35e-02 | 9.39e-02 | 4.86e-01 | 9.40e-02 | 2.13e-01 | 4.59e-01 | 3.44e-01 |
| INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS | 35 | 3.08e-01 | 4.03e-01 | 0.2490 | 0.068300 | -0.173000 | 0.067400 | -1.05e-01 | 1.08e-01 | 4.84e-01 | 7.69e-02 | 4.91e-01 | 2.83e-01 | 2.69e-01 |
| MITOTIC METAPHASE AND ANAPHASE | 205 | 2.51e-08 | 3.21e-07 | 0.2470 | -0.166000 | -0.021200 | 0.045300 | 1.76e-01 | 5.00e-03 | 4.49e-05 | 6.01e-01 | 2.65e-01 | 1.46e-05 | 9.02e-01 |
| CARGO CONCENTRATION IN THE ER | 29 | 4.05e-01 | 5.02e-01 | 0.2470 | 0.029100 | -0.037200 | -0.064000 | -1.34e-01 | 1.91e-01 | 7.86e-01 | 7.29e-01 | 5.51e-01 | 2.13e-01 | 7.45e-02 |
| RHO GTPASES ACTIVATE PAKS | 21 | 4.19e-01 | 5.16e-01 | 0.2440 | 0.132000 | -0.018300 | 0.052900 | -5.56e-02 | -1.90e-01 | 2.94e-01 | 8.85e-01 | 6.75e-01 | 6.59e-01 | 1.33e-01 |
| NUCLEOBASE BIOSYNTHESIS | 15 | 6.20e-01 | 6.86e-01 | 0.2440 | -0.175000 | 0.061900 | -0.019200 | 6.72e-02 | 1.43e-01 | 2.41e-01 | 6.78e-01 | 8.98e-01 | 6.52e-01 | 3.39e-01 |
| MYD88 INDEPENDENT TLR4 CASCADE | 91 | 1.06e-02 | 3.10e-02 | 0.2440 | 0.086300 | -0.130000 | -0.070500 | -1.08e-01 | 1.36e-01 | 1.55e-01 | 3.28e-02 | 2.46e-01 | 7.45e-02 | 2.52e-02 |
| ECM PROTEOGLYCANS | 62 | 2.79e-02 | 6.48e-02 | 0.2430 | 0.210000 | 0.046700 | 0.006660 | -1.12e-01 | 4.25e-05 | 4.22e-03 | 5.25e-01 | 9.28e-01 | 1.27e-01 | 1.00e+00 |
| MEIOTIC SYNAPSIS | 38 | 3.11e-01 | 4.06e-01 | 0.2430 | -0.092300 | 0.140000 | -0.083100 | 9.24e-02 | -1.24e-01 | 3.25e-01 | 1.36e-01 | 3.75e-01 | 3.24e-01 | 1.87e-01 |
| DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE | 20 | 6.33e-01 | 6.95e-01 | 0.2430 | 0.096200 | 0.177000 | 0.096600 | -6.20e-02 | 7.22e-02 | 4.56e-01 | 1.72e-01 | 4.54e-01 | 6.31e-01 | 5.76e-01 |
| METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS | 100 | 1.88e-02 | 4.77e-02 | 0.2420 | 0.028300 | 0.134000 | 0.031500 | 1.39e-01 | 1.41e-01 | 6.25e-01 | 2.09e-02 | 5.86e-01 | 1.64e-02 | 1.51e-02 |
| KERATAN SULFATE KERATIN METABOLISM | 30 | 5.34e-01 | 6.15e-01 | 0.2420 | 0.021900 | 0.133000 | 0.086800 | 7.92e-02 | 1.64e-01 | 8.35e-01 | 2.07e-01 | 4.11e-01 | 4.53e-01 | 1.21e-01 |
| SIGNALING BY INSULIN RECEPTOR | 59 | 4.25e-02 | 9.09e-02 | 0.2420 | 0.067800 | -0.112000 | 0.011800 | -8.26e-03 | 2.04e-01 | 3.68e-01 | 1.39e-01 | 8.75e-01 | 9.13e-01 | 6.78e-03 |
| DEFECTIVE EXT2 CAUSES EXOSTOSES 2 | 14 | 8.52e-01 | 8.77e-01 | 0.2420 | 0.082300 | 0.062500 | 0.174000 | -3.88e-02 | 1.28e-01 | 5.94e-01 | 6.86e-01 | 2.61e-01 | 8.01e-01 | 4.06e-01 |
| SUPPRESSION OF PHAGOSOMAL MATURATION | 13 | 8.43e-01 | 8.71e-01 | 0.2420 | -0.163000 | -0.067900 | -0.115000 | 1.11e-01 | -4.29e-02 | 3.10e-01 | 6.72e-01 | 4.71e-01 | 4.87e-01 | 7.89e-01 |
| TRANSCRIPTIONAL REGULATION BY RUNX1 | 174 | 4.39e-04 | 2.20e-03 | 0.2410 | -0.143000 | -0.103000 | -0.037900 | 2.83e-02 | -1.58e-01 | 1.13e-03 | 1.94e-02 | 3.89e-01 | 5.20e-01 | 3.34e-04 |
| RHOG GTPASE CYCLE | 73 | 2.21e-02 | 5.42e-02 | 0.2410 | 0.034000 | 0.017500 | -0.097300 | -1.00e-01 | 1.93e-01 | 6.16e-01 | 7.97e-01 | 1.51e-01 | 1.39e-01 | 4.40e-03 |
| SIGNALING BY HEDGEHOG | 141 | 1.54e-04 | 8.51e-04 | 0.2410 | -0.221000 | -0.082400 | -0.010800 | -1.72e-02 | -4.70e-02 | 6.22e-06 | 9.14e-02 | 8.24e-01 | 7.24e-01 | 3.36e-01 |
| TRNA PROCESSING | 105 | 2.30e-03 | 8.80e-03 | 0.2400 | 0.028300 | -0.018800 | 0.150000 | 1.82e-01 | -2.07e-02 | 6.17e-01 | 7.40e-01 | 7.78e-03 | 1.26e-03 | 7.14e-01 |
| G ALPHA Z SIGNALLING EVENTS | 44 | 2.06e-01 | 3.01e-01 | 0.2390 | -0.054900 | -0.155000 | 0.062700 | -1.56e-01 | -4.34e-02 | 5.29e-01 | 7.47e-02 | 4.72e-01 | 7.32e-02 | 6.18e-01 |
| TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES | 61 | 6.74e-02 | 1.30e-01 | 0.2380 | -0.064600 | 0.002010 | 0.108000 | 1.37e-01 | -1.50e-01 | 3.83e-01 | 9.78e-01 | 1.46e-01 | 6.52e-02 | 4.31e-02 |
| REGULATION OF TP53 EXPRESSION AND DEGRADATION | 33 | 1.73e-01 | 2.63e-01 | 0.2380 | 0.059800 | -0.175000 | -0.074500 | 2.39e-02 | 1.28e-01 | 5.53e-01 | 8.13e-02 | 4.59e-01 | 8.12e-01 | 2.03e-01 |
| SIGNALING BY ERBB2 | 47 | 3.82e-01 | 4.79e-01 | 0.2370 | -0.105000 | -0.167000 | -0.095700 | -7.80e-02 | -4.61e-02 | 2.13e-01 | 4.73e-02 | 2.56e-01 | 3.55e-01 | 5.84e-01 |
| GLYCOLYSIS | 65 | 5.24e-02 | 1.07e-01 | 0.2370 | 0.047200 | -0.058200 | 0.158000 | -2.17e-02 | 1.59e-01 | 5.11e-01 | 4.17e-01 | 2.79e-02 | 7.63e-01 | 2.64e-02 |
| SIGNALING BY EGFR | 46 | 3.29e-01 | 4.27e-01 | 0.2360 | -0.105000 | -0.118000 | -0.050700 | -1.63e-01 | -4.31e-02 | 2.19e-01 | 1.67e-01 | 5.52e-01 | 5.60e-02 | 6.13e-01 |
| REGULATION OF BETA CELL DEVELOPMENT | 24 | 6.26e-01 | 6.91e-01 | 0.2360 | 0.088600 | -0.058700 | -0.033500 | -1.99e-01 | 6.15e-02 | 4.53e-01 | 6.19e-01 | 7.76e-01 | 9.14e-02 | 6.02e-01 |
| EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION | 26 | 4.59e-01 | 5.47e-01 | 0.2360 | 0.008660 | -0.014500 | -0.037100 | -2.32e-01 | -8.59e-03 | 9.39e-01 | 8.98e-01 | 7.44e-01 | 4.05e-02 | 9.40e-01 |
| KILLING MECHANISMS | 10 | 8.81e-01 | 9.01e-01 | 0.2360 | -0.009600 | -0.087600 | 0.077400 | -2.04e-01 | 4.81e-03 | 9.58e-01 | 6.32e-01 | 6.72e-01 | 2.63e-01 | 9.79e-01 |
| TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | 13 | 8.40e-01 | 8.68e-01 | 0.2350 | -0.062500 | 0.003410 | -0.131000 | 1.34e-01 | -1.28e-01 | 6.97e-01 | 9.83e-01 | 4.15e-01 | 4.03e-01 | 4.24e-01 |
| CELL CYCLE CHECKPOINTS | 235 | 9.81e-08 | 1.15e-06 | 0.2350 | -0.165000 | -0.034600 | -0.025800 | 1.61e-01 | -1.73e-02 | 1.42e-05 | 3.62e-01 | 4.97e-01 | 2.20e-05 | 6.49e-01 |
| REPRODUCTION | 70 | 8.48e-02 | 1.56e-01 | 0.2350 | -0.145000 | 0.110000 | -0.094000 | 6.37e-02 | -9.49e-02 | 3.56e-02 | 1.12e-01 | 1.74e-01 | 3.57e-01 | 1.70e-01 |
| CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY | 22 | 4.60e-01 | 5.47e-01 | 0.2340 | 0.081400 | -0.021900 | -0.205000 | -5.70e-02 | 5.11e-02 | 5.09e-01 | 8.59e-01 | 9.64e-02 | 6.44e-01 | 6.78e-01 |
| MITOCHONDRIAL BIOGENESIS | 92 | 3.04e-04 | 1.56e-03 | 0.2340 | 0.024700 | -0.168000 | 0.035000 | 1.54e-01 | -2.98e-02 | 6.83e-01 | 5.25e-03 | 5.62e-01 | 1.08e-02 | 6.21e-01 |
| REGULATION OF INSULIN SECRETION | 70 | 3.37e-02 | 7.60e-02 | 0.2340 | 0.025500 | -0.101000 | 0.137000 | -1.57e-01 | 2.07e-02 | 7.12e-01 | 1.43e-01 | 4.77e-02 | 2.32e-02 | 7.64e-01 |
| METABOLISM OF CARBOHYDRATES | 255 | 1.13e-06 | 1.05e-05 | 0.2340 | 0.032000 | 0.105000 | 0.115000 | -7.27e-04 | 1.71e-01 | 3.80e-01 | 4.07e-03 | 1.56e-03 | 9.84e-01 | 2.60e-06 |
| REGULATION OF KIT SIGNALING | 16 | 8.09e-01 | 8.44e-01 | 0.2330 | -0.054200 | -0.175000 | -0.027500 | -1.26e-01 | 6.57e-02 | 7.07e-01 | 2.26e-01 | 8.49e-01 | 3.83e-01 | 6.49e-01 |
| RHO GTPASES ACTIVATE ROCKS | 19 | 5.07e-01 | 5.94e-01 | 0.2330 | 0.105000 | 0.032000 | -0.007100 | 4.67e-02 | -2.00e-01 | 4.27e-01 | 8.09e-01 | 9.57e-01 | 7.24e-01 | 1.31e-01 |
| SIGNALING BY NOTCH | 186 | 4.02e-04 | 2.02e-03 | 0.2320 | -0.171000 | -0.083500 | -0.039400 | 3.48e-02 | -1.22e-01 | 6.01e-05 | 4.98e-02 | 3.54e-01 | 4.14e-01 | 4.11e-03 |
| PROGRAMMED CELL DEATH | 182 | 2.49e-05 | 1.65e-04 | 0.2320 | -0.131000 | 0.020600 | -0.014500 | 1.89e-01 | -1.04e-02 | 2.28e-03 | 6.33e-01 | 7.37e-01 | 1.14e-05 | 8.09e-01 |
| INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL | 15 | 8.31e-01 | 8.62e-01 | 0.2310 | -0.121000 | -0.074900 | 0.026800 | -1.72e-02 | -1.79e-01 | 4.15e-01 | 6.15e-01 | 8.58e-01 | 9.08e-01 | 2.29e-01 |
| DNA DAMAGE BYPASS | 46 | 2.57e-01 | 3.54e-01 | 0.2310 | -0.067700 | 0.066100 | 0.084600 | 1.93e-01 | -1.02e-02 | 4.27e-01 | 4.38e-01 | 3.21e-01 | 2.38e-02 | 9.05e-01 |
| INFECTIOUS DISEASE | 711 | 1.29e-18 | 6.17e-17 | 0.2310 | -0.153000 | -0.035000 | -0.016500 | 1.24e-01 | -1.14e-01 | 5.29e-12 | 1.14e-01 | 4.55e-01 | 1.95e-08 | 2.93e-07 |
| NON INTEGRIN MEMBRANE ECM INTERACTIONS | 55 | 7.16e-02 | 1.36e-01 | 0.2300 | 0.119000 | -0.005590 | -0.046400 | -1.87e-01 | -4.22e-02 | 1.28e-01 | 9.43e-01 | 5.52e-01 | 1.68e-02 | 5.88e-01 |
| PYRIMIDINE SALVAGE | 10 | 8.70e-01 | 8.91e-01 | 0.2300 | -0.127000 | 0.078400 | 0.087200 | 1.25e-01 | 8.43e-02 | 4.86e-01 | 6.68e-01 | 6.33e-01 | 4.93e-01 | 6.44e-01 |
| RAB GEFS EXCHANGE GTP FOR GDP ON RABS | 86 | 7.31e-03 | 2.26e-02 | 0.2290 | -0.033200 | -0.040100 | 0.005270 | -7.61e-02 | 2.10e-01 | 5.95e-01 | 5.20e-01 | 9.33e-01 | 2.23e-01 | 7.65e-04 |
| RAC3 GTPASE CYCLE | 88 | 1.74e-02 | 4.48e-02 | 0.2290 | 0.060600 | 0.027900 | 0.002210 | -1.72e-01 | 1.36e-01 | 3.26e-01 | 6.51e-01 | 9.71e-01 | 5.28e-03 | 2.74e-02 |
| BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | 76 | 4.40e-02 | 9.34e-02 | 0.2290 | 0.038600 | 0.005120 | 0.114000 | 1.33e-01 | 1.41e-01 | 5.61e-01 | 9.39e-01 | 8.46e-02 | 4.46e-02 | 3.39e-02 |
| SUMOYLATION OF SUMOYLATION PROTEINS | 33 | 4.30e-01 | 5.24e-01 | 0.2280 | 0.055200 | -0.151000 | 0.094900 | -9.69e-02 | 8.95e-02 | 5.83e-01 | 1.35e-01 | 3.45e-01 | 3.35e-01 | 3.74e-01 |
| CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE | 49 | 4.00e-01 | 4.99e-01 | 0.2280 | -0.137000 | -0.140000 | -0.075600 | -6.09e-02 | -6.57e-02 | 9.73e-02 | 9.05e-02 | 3.60e-01 | 4.61e-01 | 4.26e-01 |
| SUMOYLATION OF RNA BINDING PROTEINS | 45 | 2.43e-01 | 3.41e-01 | 0.2280 | 0.038300 | -0.168000 | 0.098800 | -1.08e-01 | 2.52e-02 | 6.57e-01 | 5.08e-02 | 2.52e-01 | 2.12e-01 | 7.70e-01 |
| NUCLEAR SIGNALING BY ERBB4 | 30 | 3.91e-01 | 4.88e-01 | 0.2270 | -0.085900 | 0.133000 | -0.120000 | -3.16e-02 | -1.07e-01 | 4.16e-01 | 2.08e-01 | 2.57e-01 | 7.65e-01 | 3.11e-01 |
| RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION | 48 | 2.73e-01 | 3.71e-01 | 0.2270 | -0.012100 | -0.079800 | -0.095500 | -8.70e-02 | -1.69e-01 | 8.85e-01 | 3.39e-01 | 2.53e-01 | 2.97e-01 | 4.34e-02 |
| DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM | 39 | 5.19e-01 | 6.03e-01 | 0.2270 | 0.110000 | 0.162000 | 0.055700 | 5.34e-02 | 8.51e-02 | 2.33e-01 | 8.03e-02 | 5.47e-01 | 5.64e-01 | 3.58e-01 |
| PTEN REGULATION | 132 | 8.06e-04 | 3.68e-03 | 0.2260 | -0.140000 | -0.109000 | 0.033400 | 9.04e-02 | -1.01e-01 | 5.61e-03 | 3.03e-02 | 5.08e-01 | 7.31e-02 | 4.43e-02 |
| DEADENYLATION OF MRNA | 25 | 5.44e-01 | 6.25e-01 | 0.2260 | 0.054500 | -0.108000 | 0.176000 | -7.34e-02 | 2.39e-03 | 6.37e-01 | 3.48e-01 | 1.28e-01 | 5.26e-01 | 9.83e-01 |
| TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST | 15 | 6.28e-01 | 6.93e-01 | 0.2250 | -0.134000 | -0.042600 | 0.027800 | 2.76e-02 | 1.72e-01 | 3.69e-01 | 7.75e-01 | 8.52e-01 | 8.53e-01 | 2.50e-01 |
| G1 S SPECIFIC TRANSCRIPTION | 25 | 4.54e-01 | 5.42e-01 | 0.2250 | -0.045100 | 0.016000 | -0.014600 | 1.02e-01 | 1.94e-01 | 6.96e-01 | 8.90e-01 | 8.99e-01 | 3.80e-01 | 9.30e-02 |
| ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY | 11 | 7.62e-01 | 8.08e-01 | 0.2250 | 0.067200 | -0.104000 | -0.039700 | 1.54e-01 | -9.95e-02 | 7.00e-01 | 5.52e-01 | 8.20e-01 | 3.76e-01 | 5.68e-01 |
| TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS | 28 | 3.31e-01 | 4.28e-01 | 0.2240 | -0.064200 | 0.116000 | -0.018000 | -8.20e-02 | -1.60e-01 | 5.57e-01 | 2.89e-01 | 8.69e-01 | 4.53e-01 | 1.43e-01 |
| APOPTOSIS | 161 | 2.18e-04 | 1.16e-03 | 0.2230 | -0.138000 | 0.014000 | -0.030300 | 1.72e-01 | -2.72e-03 | 2.63e-03 | 7.60e-01 | 5.08e-01 | 1.64e-04 | 9.53e-01 |
| DISEASES OF CARBOHYDRATE METABOLISM | 29 | 4.15e-01 | 5.13e-01 | 0.2230 | -0.080600 | 0.171000 | 0.095100 | 3.84e-02 | 5.93e-02 | 4.53e-01 | 1.11e-01 | 3.76e-01 | 7.21e-01 | 5.80e-01 |
| INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | 34 | 4.73e-01 | 5.60e-01 | 0.2230 | 0.101000 | -0.099300 | 0.072000 | -4.26e-02 | 1.50e-01 | 3.07e-01 | 3.16e-01 | 4.68e-01 | 6.68e-01 | 1.30e-01 |
| IRON UPTAKE AND TRANSPORT | 52 | 1.38e-01 | 2.23e-01 | 0.2230 | -0.080300 | 0.055600 | -0.052200 | 1.72e-01 | 8.80e-02 | 3.17e-01 | 4.88e-01 | 5.15e-01 | 3.18e-02 | 2.72e-01 |
| SIGNALING BY FGFR2 | 60 | 1.26e-01 | 2.09e-01 | 0.2230 | -0.069100 | -0.079500 | 0.019900 | 9.33e-02 | -1.72e-01 | 3.55e-01 | 2.87e-01 | 7.90e-01 | 2.12e-01 | 2.16e-02 |
| CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | 31 | 5.66e-01 | 6.43e-01 | 0.2230 | 0.162000 | 0.127000 | 0.020300 | 5.25e-02 | 6.38e-02 | 1.19e-01 | 2.20e-01 | 8.45e-01 | 6.13e-01 | 5.39e-01 |
| PEPTIDE LIGAND BINDING RECEPTORS | 84 | 5.31e-03 | 1.74e-02 | 0.2230 | -0.095200 | 0.096000 | -0.005220 | -9.07e-02 | -1.52e-01 | 1.32e-01 | 1.29e-01 | 9.34e-01 | 1.51e-01 | 1.63e-02 |
| RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA | 24 | 4.89e-01 | 5.77e-01 | 0.2230 | 0.048200 | 0.022800 | -0.154000 | -1.28e-01 | -8.09e-02 | 6.83e-01 | 8.47e-01 | 1.91e-01 | 2.78e-01 | 4.93e-01 |
| MUSCLE CONTRACTION | 150 | 3.06e-03 | 1.11e-02 | 0.2230 | 0.191000 | 0.006950 | 0.091400 | -5.32e-02 | 4.19e-02 | 5.39e-05 | 8.83e-01 | 5.36e-02 | 2.61e-01 | 3.76e-01 |
| DISEASES OF MITOTIC CELL CYCLE | 37 | 2.81e-01 | 3.76e-01 | 0.2230 | -0.186000 | 0.043800 | 0.054400 | 3.60e-02 | -9.32e-02 | 5.00e-02 | 6.45e-01 | 5.67e-01 | 7.05e-01 | 3.27e-01 |
| RAB REGULATION OF TRAFFICKING | 115 | 1.33e-03 | 5.47e-03 | 0.2220 | -0.016400 | -0.038000 | 0.060800 | -5.37e-02 | 2.03e-01 | 7.62e-01 | 4.82e-01 | 2.60e-01 | 3.20e-01 | 1.73e-04 |
| INITIATION OF NUCLEAR ENVELOPE NE REFORMATION | 16 | 7.65e-01 | 8.09e-01 | 0.2220 | -0.103000 | 0.114000 | 0.125000 | 9.88e-02 | 2.29e-02 | 4.75e-01 | 4.32e-01 | 3.88e-01 | 4.94e-01 | 8.74e-01 |
| THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS | 24 | 3.56e-01 | 4.54e-01 | 0.2220 | -0.151000 | -0.120000 | 0.088200 | 2.30e-02 | 6.25e-02 | 2.02e-01 | 3.10e-01 | 4.54e-01 | 8.46e-01 | 5.96e-01 |
| ACYL CHAIN REMODELLING OF PC | 16 | 6.93e-01 | 7.43e-01 | 0.2220 | -0.120000 | -0.091900 | 0.113000 | -8.67e-02 | -7.70e-02 | 4.06e-01 | 5.25e-01 | 4.34e-01 | 5.48e-01 | 5.94e-01 |
| FC EPSILON RECEPTOR FCERI SIGNALING | 122 | 1.07e-03 | 4.64e-03 | 0.2210 | -0.157000 | -0.083500 | -0.045900 | 1.23e-01 | 7.69e-04 | 2.74e-03 | 1.12e-01 | 3.82e-01 | 1.90e-02 | 9.88e-01 |
| MITOTIC G2 G2 M PHASES | 182 | 4.64e-05 | 2.91e-04 | 0.2210 | -0.125000 | 0.012400 | 0.059300 | 1.69e-01 | -3.14e-02 | 3.67e-03 | 7.74e-01 | 1.68e-01 | 8.50e-05 | 4.66e-01 |
| RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK | 48 | 1.88e-01 | 2.77e-01 | 0.2210 | 0.011100 | -0.011200 | 0.121000 | 2.86e-02 | 1.82e-01 | 8.95e-01 | 8.94e-01 | 1.46e-01 | 7.32e-01 | 2.93e-02 |
| TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | 166 | 1.32e-04 | 7.41e-04 | 0.2210 | 0.006790 | 0.009890 | 0.114000 | 2.83e-02 | 1.87e-01 | 8.80e-01 | 8.26e-01 | 1.17e-02 | 5.30e-01 | 3.28e-05 |
| DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | 26 | 6.81e-01 | 7.33e-01 | 0.2200 | -0.195000 | -0.040100 | -0.072000 | -3.84e-02 | -4.94e-02 | 8.60e-02 | 7.23e-01 | 5.25e-01 | 7.34e-01 | 6.63e-01 |
| ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | 74 | 4.38e-02 | 9.33e-02 | 0.2200 | -0.049600 | -0.201000 | 0.037300 | -6.10e-02 | 2.15e-02 | 4.61e-01 | 2.80e-03 | 5.80e-01 | 3.65e-01 | 7.49e-01 |
| WNT LIGAND BIOGENESIS AND TRAFFICKING | 18 | 6.52e-01 | 7.10e-01 | 0.2200 | -0.163000 | -0.125000 | -0.029600 | 1.32e-02 | 7.18e-02 | 2.31e-01 | 3.60e-01 | 8.28e-01 | 9.23e-01 | 5.98e-01 |
| VIRAL MESSENGER RNA SYNTHESIS | 42 | 1.73e-01 | 2.63e-01 | 0.2200 | 0.030800 | -0.110000 | 0.148000 | 1.12e-01 | -2.93e-02 | 7.30e-01 | 2.17e-01 | 9.77e-02 | 2.10e-01 | 7.43e-01 |
| CHROMATIN MODIFYING ENZYMES | 216 | 7.62e-05 | 4.50e-04 | 0.2190 | 0.058100 | -0.167000 | 0.025500 | -1.19e-01 | -4.21e-02 | 1.42e-01 | 2.38e-05 | 5.19e-01 | 2.59e-03 | 2.87e-01 |
| P75 NTR RECEPTOR MEDIATED SIGNALLING | 93 | 5.08e-02 | 1.05e-01 | 0.2190 | 0.079300 | -0.068200 | 0.033700 | -1.16e-01 | 1.50e-01 | 1.87e-01 | 2.56e-01 | 5.74e-01 | 5.42e-02 | 1.27e-02 |
| OXIDATIVE STRESS INDUCED SENESCENCE | 76 | 1.68e-01 | 2.58e-01 | 0.2190 | -0.104000 | -0.131000 | -0.046800 | -9.80e-03 | -1.33e-01 | 1.16e-01 | 4.93e-02 | 4.81e-01 | 8.83e-01 | 4.58e-02 |
| TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY | 11 | 9.29e-01 | 9.39e-01 | 0.2180 | -0.168000 | -0.105000 | -0.081200 | 2.89e-02 | -2.41e-02 | 3.34e-01 | 5.46e-01 | 6.41e-01 | 8.68e-01 | 8.90e-01 |
| NEUTROPHIL DEGRANULATION | 378 | 7.04e-11 | 1.31e-09 | 0.2180 | -0.104000 | -0.006310 | -0.135000 | 1.33e-01 | 2.21e-02 | 5.52e-04 | 8.34e-01 | 6.56e-06 | 9.62e-06 | 4.61e-01 |
| TRIGLYCERIDE METABOLISM | 22 | 5.53e-01 | 6.33e-01 | 0.2160 | -0.105000 | -0.018900 | -0.076000 | 1.39e-01 | 1.01e-01 | 3.93e-01 | 8.78e-01 | 5.37e-01 | 2.58e-01 | 4.11e-01 |
| TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE | 90 | 4.72e-02 | 9.94e-02 | 0.2160 | 0.079700 | -0.083100 | -0.018400 | -9.16e-02 | 1.58e-01 | 1.92e-01 | 1.73e-01 | 7.63e-01 | 1.33e-01 | 9.81e-03 |
| CLASS A 1 RHODOPSIN LIKE RECEPTORS | 150 | 1.08e-05 | 7.85e-05 | 0.2160 | -0.046800 | 0.049200 | 0.017400 | -1.91e-01 | -7.44e-02 | 3.23e-01 | 2.99e-01 | 7.14e-01 | 5.73e-05 | 1.16e-01 |
| IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX | 10 | 9.29e-01 | 9.39e-01 | 0.2160 | 0.026700 | 0.101000 | -0.018800 | 1.65e-01 | -9.10e-02 | 8.84e-01 | 5.81e-01 | 9.18e-01 | 3.67e-01 | 6.18e-01 |
| OTHER INTERLEUKIN SIGNALING | 19 | 6.77e-01 | 7.29e-01 | 0.2160 | 0.086700 | -0.190000 | 0.028800 | -1.25e-02 | 4.57e-02 | 5.13e-01 | 1.52e-01 | 8.28e-01 | 9.25e-01 | 7.30e-01 |
| BASIGIN INTERACTIONS | 22 | 6.33e-01 | 6.95e-01 | 0.2150 | -0.136000 | 0.135000 | -0.095900 | -1.21e-02 | 8.71e-04 | 2.69e-01 | 2.72e-01 | 4.36e-01 | 9.22e-01 | 9.94e-01 |
| MAP2K AND MAPK ACTIVATION | 36 | 3.64e-01 | 4.61e-01 | 0.2150 | -0.104000 | -0.177000 | 0.001510 | -5.02e-02 | 3.90e-02 | 2.81e-01 | 6.60e-02 | 9.88e-01 | 6.02e-01 | 6.86e-01 |
| EPH EPHRIN MEDIATED REPULSION OF CELLS | 49 | 1.40e-01 | 2.25e-01 | 0.2140 | -0.012100 | -0.045300 | 0.114000 | -1.73e-01 | 2.48e-02 | 8.83e-01 | 5.83e-01 | 1.69e-01 | 3.62e-02 | 7.64e-01 |
| ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | 32 | 4.03e-01 | 5.01e-01 | 0.2130 | -0.048500 | 0.037700 | -0.124000 | 1.51e-01 | 5.82e-02 | 6.35e-01 | 7.12e-01 | 2.23e-01 | 1.39e-01 | 5.69e-01 |
| MATURATION OF SARS COV 2 SPIKE PROTEIN | 29 | 5.18e-01 | 6.03e-01 | 0.2130 | -0.071100 | -0.157000 | -0.013500 | -7.98e-02 | 9.59e-02 | 5.08e-01 | 1.44e-01 | 9.00e-01 | 4.57e-01 | 3.71e-01 |
| G ALPHA S SIGNALLING EVENTS | 94 | 1.88e-02 | 4.77e-02 | 0.2120 | 0.071700 | -0.020600 | 0.117000 | -1.61e-01 | 2.65e-03 | 2.30e-01 | 7.30e-01 | 5.04e-02 | 7.12e-03 | 9.65e-01 |
| TELOMERE C STRAND LAGGING STRAND SYNTHESIS | 33 | 5.16e-01 | 6.02e-01 | 0.2110 | 0.040100 | 0.062900 | 0.018000 | 1.92e-01 | -4.38e-02 | 6.90e-01 | 5.32e-01 | 8.58e-01 | 5.70e-02 | 6.63e-01 |
| SIGNALING BY NOTCH2 | 33 | 3.17e-01 | 4.13e-01 | 0.2110 | -0.075500 | 0.040800 | 0.003380 | -1.48e-01 | -1.23e-01 | 4.53e-01 | 6.85e-01 | 9.73e-01 | 1.42e-01 | 2.21e-01 |
| SNRNP ASSEMBLY | 51 | 1.50e-01 | 2.38e-01 | 0.2100 | -0.066800 | -0.055600 | 0.123000 | 1.34e-01 | -5.95e-02 | 4.09e-01 | 4.92e-01 | 1.29e-01 | 9.79e-02 | 4.63e-01 |
| THE PHOTOTRANSDUCTION CASCADE | 18 | 7.86e-01 | 8.28e-01 | 0.2100 | 0.123000 | -0.030300 | 0.149000 | 1.83e-02 | -7.41e-02 | 3.65e-01 | 8.24e-01 | 2.75e-01 | 8.93e-01 | 5.86e-01 |
| PLATELET HOMEOSTASIS | 77 | 1.57e-01 | 2.46e-01 | 0.2100 | 0.114000 | -0.071500 | 0.091700 | -1.06e-01 | 7.87e-02 | 8.32e-02 | 2.79e-01 | 1.65e-01 | 1.09e-01 | 2.33e-01 |
| TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST | 12 | 7.98e-01 | 8.35e-01 | 0.2090 | -0.119000 | -0.005810 | 0.041100 | 3.71e-02 | 1.63e-01 | 4.76e-01 | 9.72e-01 | 8.05e-01 | 8.24e-01 | 3.28e-01 |
| TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE | 63 | 2.95e-02 | 6.81e-02 | 0.2080 | -0.041400 | -0.121000 | 0.085600 | 7.32e-02 | 1.20e-01 | 5.70e-01 | 9.71e-02 | 2.40e-01 | 3.16e-01 | 9.90e-02 |
| NEGATIVE REGULATION OF FGFR2 SIGNALING | 25 | 7.05e-01 | 7.52e-01 | 0.2080 | 0.123000 | -0.084500 | 0.113000 | 1.33e-02 | 9.05e-02 | 2.88e-01 | 4.65e-01 | 3.26e-01 | 9.08e-01 | 4.34e-01 |
| SUMOYLATION OF DNA REPLICATION PROTEINS | 43 | 2.43e-01 | 3.41e-01 | 0.2080 | -0.021800 | -0.142000 | 0.082400 | -6.32e-02 | 1.09e-01 | 8.05e-01 | 1.07e-01 | 3.50e-01 | 4.73e-01 | 2.16e-01 |
| RAB GERANYLGERANYLATION | 57 | 1.20e-01 | 2.03e-01 | 0.2080 | -0.090000 | 0.026300 | 0.019000 | 1.55e-01 | 1.00e-01 | 2.40e-01 | 7.32e-01 | 8.04e-01 | 4.26e-02 | 1.92e-01 |
| METABOLISM OF VITAMINS AND COFACTORS | 147 | 1.10e-02 | 3.15e-02 | 0.2080 | 0.016500 | 0.132000 | -0.002480 | 1.40e-01 | 7.60e-02 | 7.31e-01 | 5.70e-03 | 9.59e-01 | 3.43e-03 | 1.12e-01 |
| DEGRADATION OF THE EXTRACELLULAR MATRIX | 101 | 4.78e-03 | 1.59e-02 | 0.2080 | 0.107000 | 0.090900 | 0.031500 | -1.50e-01 | -4.98e-03 | 6.32e-02 | 1.15e-01 | 5.85e-01 | 9.43e-03 | 9.31e-01 |
| FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES | 23 | 7.01e-01 | 7.49e-01 | 0.2070 | 0.105000 | -0.076000 | -0.038700 | -1.46e-01 | -5.72e-02 | 3.85e-01 | 5.28e-01 | 7.48e-01 | 2.24e-01 | 6.35e-01 |
| MET ACTIVATES PTK2 SIGNALING | 28 | 4.31e-01 | 5.24e-01 | 0.2070 | 0.127000 | 0.025400 | -0.003080 | -1.35e-01 | -8.91e-02 | 2.46e-01 | 8.16e-01 | 9.78e-01 | 2.16e-01 | 4.14e-01 |
| EPIGENETIC REGULATION OF GENE EXPRESSION | 100 | 3.23e-02 | 7.36e-02 | 0.2070 | -0.047000 | -0.052900 | 0.010800 | 6.55e-02 | -1.83e-01 | 4.17e-01 | 3.61e-01 | 8.52e-01 | 2.58e-01 | 1.60e-03 |
| TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS | 44 | 4.02e-01 | 5.01e-01 | 0.2060 | -0.160000 | -0.105000 | -0.008940 | -5.54e-02 | -5.33e-02 | 6.68e-02 | 2.27e-01 | 9.18e-01 | 5.25e-01 | 5.41e-01 |
| TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES | 44 | 2.09e-01 | 3.02e-01 | 0.2040 | -0.101000 | -0.097500 | 0.036700 | -9.87e-02 | 1.05e-01 | 2.48e-01 | 2.63e-01 | 6.74e-01 | 2.57e-01 | 2.30e-01 |
| NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS | 52 | 1.56e-01 | 2.45e-01 | 0.2040 | 0.053500 | -0.114000 | -0.159000 | -2.02e-02 | -7.37e-03 | 5.04e-01 | 1.55e-01 | 4.76e-02 | 8.01e-01 | 9.27e-01 |
| SIGNALING BY FGFR | 70 | 1.92e-01 | 2.82e-01 | 0.2040 | -0.071700 | -0.111000 | 0.001370 | 7.68e-03 | -1.55e-01 | 3.00e-01 | 1.10e-01 | 9.84e-01 | 9.12e-01 | 2.48e-02 |
| ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | 37 | 2.20e-01 | 3.14e-01 | 0.2030 | -0.031200 | -0.109000 | 0.054700 | 1.51e-01 | 5.10e-02 | 7.43e-01 | 2.52e-01 | 5.65e-01 | 1.11e-01 | 5.92e-01 |
| SIGNALING BY GPCR | 437 | 8.34e-10 | 1.33e-08 | 0.2030 | 0.040800 | -0.046200 | 0.062600 | -1.74e-01 | 5.64e-02 | 1.45e-01 | 9.87e-02 | 2.53e-02 | 5.67e-10 | 4.42e-02 |
| NEGATIVE REGULATION OF FGFR3 SIGNALING | 23 | 8.33e-01 | 8.63e-01 | 0.2020 | 0.131000 | 0.014900 | 0.065300 | 5.17e-02 | 1.28e-01 | 2.75e-01 | 9.01e-01 | 5.88e-01 | 6.68e-01 | 2.87e-01 |
| METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES | 20 | 7.78e-01 | 8.22e-01 | 0.2010 | -0.008610 | 0.108000 | -0.099900 | 1.35e-01 | -2.30e-02 | 9.47e-01 | 4.02e-01 | 4.39e-01 | 2.96e-01 | 8.59e-01 |
| DEATH RECEPTOR SIGNALLING | 132 | 2.45e-02 | 5.86e-02 | 0.2010 | 0.075200 | -0.089300 | 0.024200 | -1.22e-01 | 1.07e-01 | 1.36e-01 | 7.67e-02 | 6.32e-01 | 1.59e-02 | 3.43e-02 |
| MHC CLASS II ANTIGEN PRESENTATION | 101 | 1.22e-01 | 2.05e-01 | 0.2010 | 0.065600 | 0.060500 | 0.082700 | 8.30e-02 | 1.37e-01 | 2.55e-01 | 2.94e-01 | 1.51e-01 | 1.50e-01 | 1.78e-02 |
| SUMOYLATION | 157 | 1.64e-02 | 4.32e-02 | 0.2010 | -0.003700 | -0.139000 | -0.016400 | -1.42e-01 | -2.39e-02 | 9.36e-01 | 2.69e-03 | 7.23e-01 | 2.18e-03 | 6.06e-01 |
| NEGATIVE REGULATION OF FLT3 | 14 | 8.69e-01 | 8.91e-01 | 0.2010 | 0.086400 | -0.006480 | 0.089600 | 1.35e-01 | -8.00e-02 | 5.76e-01 | 9.67e-01 | 5.62e-01 | 3.80e-01 | 6.04e-01 |
| TOLL LIKE RECEPTOR CASCADES | 134 | 5.65e-03 | 1.84e-02 | 0.2000 | 0.041700 | -0.047400 | -0.099600 | -7.10e-02 | 1.45e-01 | 4.05e-01 | 3.44e-01 | 4.66e-02 | 1.56e-01 | 3.71e-03 |
| EXTRACELLULAR MATRIX ORGANIZATION | 232 | 8.73e-07 | 8.38e-06 | 0.2000 | 0.092200 | 0.054500 | -0.044400 | -1.62e-01 | -1.84e-02 | 1.58e-02 | 1.53e-01 | 2.45e-01 | 2.31e-05 | 6.29e-01 |
| GPCR LIGAND BINDING | 224 | 1.32e-07 | 1.50e-06 | 0.2000 | -0.095900 | 0.058300 | 0.022600 | -1.44e-01 | -7.74e-02 | 1.36e-02 | 1.34e-01 | 5.61e-01 | 2.06e-04 | 4.65e-02 |
| NUCLEAR ENVELOPE NE REASSEMBLY | 63 | 9.44e-02 | 1.69e-01 | 0.2000 | -0.061200 | -0.004340 | 0.147000 | 1.05e-01 | 5.72e-02 | 4.01e-01 | 9.52e-01 | 4.32e-02 | 1.49e-01 | 4.33e-01 |
| RESOLUTION OF D LOOP STRUCTURES | 30 | 3.73e-01 | 4.70e-01 | 0.1990 | 0.167000 | 0.063200 | -0.068600 | -4.78e-02 | -3.19e-02 | 1.14e-01 | 5.49e-01 | 5.16e-01 | 6.50e-01 | 7.63e-01 |
| PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE | 46 | 4.51e-01 | 5.40e-01 | 0.1990 | 0.030100 | 0.118000 | 0.046500 | 4.08e-03 | 1.51e-01 | 7.24e-01 | 1.66e-01 | 5.85e-01 | 9.62e-01 | 7.69e-02 |
| UB SPECIFIC PROCESSING PROTEASES | 163 | 5.08e-04 | 2.48e-03 | 0.1990 | -0.117000 | -0.126000 | -0.056100 | 8.42e-02 | -8.80e-03 | 1.02e-02 | 5.75e-03 | 2.17e-01 | 6.40e-02 | 8.47e-01 |
| TRNA PROCESSING IN THE NUCLEUS | 56 | 1.13e-01 | 1.94e-01 | 0.1980 | -0.006390 | -0.114000 | 0.125000 | 1.00e-01 | -2.34e-02 | 9.34e-01 | 1.39e-01 | 1.05e-01 | 1.96e-01 | 7.62e-01 |
| SUMOYLATION OF INTRACELLULAR RECEPTORS | 24 | 5.99e-01 | 6.67e-01 | 0.1980 | -0.014000 | 0.051500 | -0.023200 | -1.78e-01 | 6.39e-02 | 9.05e-01 | 6.62e-01 | 8.44e-01 | 1.30e-01 | 5.88e-01 |
| DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS | 48 | 2.80e-01 | 3.76e-01 | 0.1980 | 0.079400 | 0.056900 | -0.033800 | -1.52e-01 | 7.45e-02 | 3.41e-01 | 4.95e-01 | 6.86e-01 | 6.92e-02 | 3.72e-01 |
| EPH EPHRIN SIGNALING | 90 | 5.10e-02 | 1.05e-01 | 0.1980 | -0.006840 | -0.111000 | 0.094500 | -1.26e-01 | -4.49e-02 | 9.11e-01 | 6.80e-02 | 1.21e-01 | 3.94e-02 | 4.62e-01 |
| O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS | 33 | 3.73e-01 | 4.70e-01 | 0.1980 | 0.108000 | 0.036700 | -0.080900 | -1.31e-01 | -4.99e-02 | 2.83e-01 | 7.16e-01 | 4.21e-01 | 1.94e-01 | 6.20e-01 |
| HIV LIFE CYCLE | 142 | 5.89e-03 | 1.89e-02 | 0.1980 | -0.089100 | 0.006920 | 0.074300 | 1.41e-01 | -7.57e-02 | 6.70e-02 | 8.87e-01 | 1.27e-01 | 3.78e-03 | 1.20e-01 |
| GOLGI ASSOCIATED VESICLE BIOGENESIS | 54 | 1.74e-01 | 2.64e-01 | 0.1970 | -0.044100 | -0.002730 | -0.017500 | -3.99e-02 | 1.87e-01 | 5.75e-01 | 9.72e-01 | 8.24e-01 | 6.13e-01 | 1.73e-02 |
| O LINKED GLYCOSYLATION | 82 | 1.26e-01 | 2.09e-01 | 0.1970 | 0.083700 | 0.053000 | 0.030100 | -1.11e-01 | 1.26e-01 | 1.90e-01 | 4.07e-01 | 6.38e-01 | 8.28e-02 | 4.84e-02 |
| DNA REPAIR | 287 | 3.23e-05 | 2.10e-04 | 0.1970 | -0.009010 | 0.052800 | 0.065600 | 1.74e-01 | -3.75e-02 | 7.93e-01 | 1.25e-01 | 5.65e-02 | 4.03e-07 | 2.76e-01 |
| SARS COV 1 INFECTION | 48 | 2.20e-01 | 3.14e-01 | 0.1970 | -0.070500 | 0.016700 | 0.162000 | 8.11e-02 | 2.80e-02 | 3.98e-01 | 8.41e-01 | 5.28e-02 | 3.31e-01 | 7.37e-01 |
| BETA CATENIN INDEPENDENT WNT SIGNALING | 136 | 4.72e-03 | 1.57e-02 | 0.1960 | -0.162000 | -0.027700 | 0.014800 | 1.02e-01 | -3.30e-02 | 1.16e-03 | 5.78e-01 | 7.67e-01 | 4.03e-02 | 5.08e-01 |
| SYNDECAN INTERACTIONS | 26 | 4.58e-01 | 5.46e-01 | 0.1950 | 0.131000 | 0.086700 | -0.088600 | -5.72e-02 | -4.92e-02 | 2.48e-01 | 4.44e-01 | 4.34e-01 | 6.14e-01 | 6.64e-01 |
| TIE2 SIGNALING | 17 | 9.10e-01 | 9.24e-01 | 0.1940 | 0.000365 | -0.147000 | -0.079500 | -9.30e-02 | 3.04e-02 | 9.98e-01 | 2.93e-01 | 5.70e-01 | 5.07e-01 | 8.28e-01 |
| IRAK1 RECRUITS IKK COMPLEX | 14 | 9.48e-01 | 9.56e-01 | 0.1930 | -0.065600 | -0.025900 | -0.124000 | -6.47e-02 | -1.14e-01 | 6.71e-01 | 8.67e-01 | 4.23e-01 | 6.75e-01 | 4.60e-01 |
| DEADENYLATION DEPENDENT MRNA DECAY | 55 | 2.28e-01 | 3.23e-01 | 0.1930 | -0.006500 | -0.039800 | 0.142000 | 1.10e-01 | -5.78e-02 | 9.34e-01 | 6.10e-01 | 6.94e-02 | 1.59e-01 | 4.59e-01 |
| ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | 282 | 9.99e-09 | 1.39e-07 | 0.1930 | -0.077400 | -0.038600 | 0.092400 | 6.60e-02 | 1.29e-01 | 2.57e-02 | 2.66e-01 | 7.75e-03 | 5.70e-02 | 1.95e-04 |
| SIGNALING BY PDGF | 53 | 4.25e-01 | 5.20e-01 | 0.1910 | 0.079300 | -0.120000 | -0.006770 | -9.76e-02 | 7.86e-02 | 3.18e-01 | 1.30e-01 | 9.32e-01 | 2.19e-01 | 3.23e-01 |
| SUMOYLATION OF IMMUNE RESPONSE PROTEINS | 11 | 9.54e-01 | 9.61e-01 | 0.1910 | -0.064300 | 0.093400 | -0.045100 | 6.06e-02 | -1.34e-01 | 7.12e-01 | 5.92e-01 | 7.95e-01 | 7.28e-01 | 4.42e-01 |
| TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE | 19 | 8.93e-01 | 9.10e-01 | 0.1900 | 0.029800 | 0.137000 | -0.009190 | 1.28e-01 | 5.08e-03 | 8.22e-01 | 3.02e-01 | 9.45e-01 | 3.36e-01 | 9.69e-01 |
| SIGNALING BY WNT | 260 | 2.02e-04 | 1.09e-03 | 0.1900 | -0.158000 | -0.082800 | -0.059500 | -2.29e-02 | -8.03e-03 | 1.21e-05 | 2.18e-02 | 9.96e-02 | 5.26e-01 | 8.24e-01 |
| GLYCEROPHOSPHOLIPID BIOSYNTHESIS | 106 | 2.81e-02 | 6.51e-02 | 0.1890 | 0.080000 | -0.073900 | 0.001810 | 1.35e-02 | 1.54e-01 | 1.55e-01 | 1.89e-01 | 9.74e-01 | 8.11e-01 | 6.09e-03 |
| DISEASES OF GLYCOSYLATION | 121 | 1.38e-01 | 2.23e-01 | 0.1890 | 0.074400 | 0.086700 | 0.083600 | 3.08e-02 | 1.21e-01 | 1.58e-01 | 1.00e-01 | 1.13e-01 | 5.58e-01 | 2.14e-02 |
| NICOTINATE METABOLISM | 24 | 6.98e-01 | 7.47e-01 | 0.1890 | -0.152000 | 0.090700 | 0.034600 | 5.22e-02 | -1.65e-02 | 1.97e-01 | 4.42e-01 | 7.70e-01 | 6.58e-01 | 8.89e-01 |
| MITOCHONDRIAL TRNA AMINOACYLATION | 21 | 7.12e-01 | 7.59e-01 | 0.1880 | -0.125000 | 0.051100 | 0.100000 | 7.87e-02 | 2.95e-02 | 3.20e-01 | 6.85e-01 | 4.26e-01 | 5.32e-01 | 8.15e-01 |
| CLATHRIN MEDIATED ENDOCYTOSIS | 128 | 4.31e-02 | 9.20e-02 | 0.1880 | 0.064400 | -0.035800 | 0.081100 | -9.55e-02 | 1.19e-01 | 2.09e-01 | 4.84e-01 | 1.14e-01 | 6.24e-02 | 2.00e-02 |
| ENDOGENOUS STEROLS | 20 | 7.15e-01 | 7.62e-01 | 0.1870 | 0.082400 | -0.009480 | -0.007610 | 2.49e-02 | -1.66e-01 | 5.24e-01 | 9.42e-01 | 9.53e-01 | 8.47e-01 | 2.00e-01 |
| PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE | 19 | 8.17e-01 | 8.51e-01 | 0.1860 | -0.116000 | 0.051200 | -0.043600 | 9.91e-02 | 8.26e-02 | 3.81e-01 | 6.99e-01 | 7.42e-01 | 4.55e-01 | 5.33e-01 |
| INTRINSIC PATHWAY FOR APOPTOSIS | 52 | 3.26e-01 | 4.24e-01 | 0.1850 | -0.039200 | 0.007170 | 0.030700 | 1.77e-01 | 1.90e-02 | 6.25e-01 | 9.29e-01 | 7.02e-01 | 2.76e-02 | 8.13e-01 |
| POLO LIKE KINASE MEDIATED EVENTS | 13 | 9.18e-01 | 9.30e-01 | 0.1840 | 0.016100 | -0.090900 | 0.051600 | 4.04e-03 | -1.51e-01 | 9.20e-01 | 5.70e-01 | 7.47e-01 | 9.80e-01 | 3.47e-01 |
| MEMBRANE TRAFFICKING | 567 | 7.79e-12 | 1.87e-10 | 0.1840 | 0.004150 | -0.026000 | 0.061200 | -3.87e-02 | 1.67e-01 | 8.67e-01 | 2.92e-01 | 1.32e-02 | 1.17e-01 | 1.34e-11 |
| ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES | 48 | 3.53e-01 | 4.50e-01 | 0.1830 | 0.039400 | -0.034300 | 0.083200 | -1.45e-01 | -5.39e-02 | 6.37e-01 | 6.82e-01 | 3.19e-01 | 8.33e-02 | 5.19e-01 |
| REGULATION OF PTEN GENE TRANSCRIPTION | 57 | 3.02e-01 | 3.96e-01 | 0.1830 | -0.010300 | -0.101000 | 0.088600 | -1.12e-01 | -5.11e-02 | 8.93e-01 | 1.87e-01 | 2.47e-01 | 1.43e-01 | 5.05e-01 |
| TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX | 11 | 9.70e-01 | 9.74e-01 | 0.1830 | -0.083200 | 0.089800 | -0.029300 | 8.83e-02 | -9.87e-02 | 6.33e-01 | 6.06e-01 | 8.66e-01 | 6.12e-01 | 5.71e-01 |
| FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES | 15 | 7.99e-01 | 8.35e-01 | 0.1810 | 0.011500 | -0.157000 | -0.006370 | 8.69e-02 | 2.46e-02 | 9.39e-01 | 2.93e-01 | 9.66e-01 | 5.60e-01 | 8.69e-01 |
| EXTENSION OF TELOMERES | 48 | 4.20e-01 | 5.17e-01 | 0.1810 | 0.014400 | 0.028900 | -0.000120 | 1.58e-01 | -8.30e-02 | 8.63e-01 | 7.29e-01 | 9.99e-01 | 5.83e-02 | 3.20e-01 |
| ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS | 63 | 2.76e-01 | 3.73e-01 | 0.1810 | -0.016500 | -0.045800 | -0.048300 | 6.34e-02 | -1.55e-01 | 8.20e-01 | 5.30e-01 | 5.08e-01 | 3.84e-01 | 3.30e-02 |
| GOLGI TO ER RETROGRADE TRANSPORT | 119 | 9.83e-03 | 2.91e-02 | 0.1810 | -0.038000 | 0.001860 | 0.100000 | -7.34e-03 | 1.46e-01 | 4.74e-01 | 9.72e-01 | 5.96e-02 | 8.90e-01 | 6.00e-03 |
| GENE SILENCING BY RNA | 81 | 1.40e-01 | 2.25e-01 | 0.1800 | -0.024100 | -0.123000 | -0.041800 | 5.29e-02 | -1.10e-01 | 7.08e-01 | 5.64e-02 | 5.16e-01 | 4.10e-01 | 8.74e-02 |
| PRE NOTCH EXPRESSION AND PROCESSING | 61 | 4.67e-01 | 5.54e-01 | 0.1800 | -0.041800 | -0.039000 | -0.150000 | -6.93e-02 | -4.16e-02 | 5.72e-01 | 5.98e-01 | 4.32e-02 | 3.49e-01 | 5.74e-01 |
| DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS | 358 | 9.66e-05 | 5.59e-04 | 0.1800 | -0.046000 | -0.130000 | -0.039100 | -1.06e-01 | 2.08e-02 | 1.36e-01 | 2.46e-05 | 2.05e-01 | 6.03e-04 | 5.00e-01 |
| SIGNALING BY PTK6 | 50 | 4.92e-01 | 5.80e-01 | 0.1790 | -0.098100 | -0.049500 | -0.105000 | -6.99e-02 | 6.44e-02 | 2.30e-01 | 5.45e-01 | 1.98e-01 | 3.92e-01 | 4.31e-01 |
| TRANSPORT OF SMALL MOLECULES | 547 | 3.71e-07 | 3.85e-06 | 0.1790 | 0.086900 | 0.027800 | 0.043100 | -6.04e-03 | 1.48e-01 | 5.43e-04 | 2.69e-01 | 8.60e-02 | 8.10e-01 | 3.70e-09 |
| MET PROMOTES CELL MOTILITY | 38 | 6.71e-01 | 7.24e-01 | 0.1780 | 0.030800 | -0.051400 | -0.070000 | -1.51e-01 | -2.04e-02 | 7.42e-01 | 5.83e-01 | 4.56e-01 | 1.07e-01 | 8.28e-01 |
| INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC | 185 | 7.03e-04 | 3.29e-03 | 0.1780 | -0.023200 | -0.010100 | 0.069300 | -1.40e-03 | 1.62e-01 | 5.87e-01 | 8.14e-01 | 1.04e-01 | 9.74e-01 | 1.47e-04 |
| MAPK FAMILY SIGNALING CASCADES | 279 | 2.72e-05 | 1.78e-04 | 0.1770 | -0.053000 | -0.149000 | 0.024800 | -5.81e-02 | 4.92e-02 | 1.29e-01 | 1.94e-05 | 4.76e-01 | 9.57e-02 | 1.58e-01 |
| RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES | 78 | 1.69e-01 | 2.60e-01 | 0.1750 | -0.010800 | 0.053800 | 0.149000 | 1.49e-02 | 7.36e-02 | 8.70e-01 | 4.12e-01 | 2.32e-02 | 8.21e-01 | 2.62e-01 |
| ASPARAGINE N LINKED GLYCOSYLATION | 279 | 2.39e-06 | 2.10e-05 | 0.1750 | -0.032700 | -0.037100 | 0.091200 | 4.73e-02 | 1.33e-01 | 3.48e-01 | 2.88e-01 | 8.93e-03 | 1.75e-01 | 1.35e-04 |
| COSTIMULATION BY THE CD28 FAMILY | 47 | 5.93e-01 | 6.64e-01 | 0.1750 | 0.013200 | -0.073000 | -0.056200 | -1.12e-01 | 9.65e-02 | 8.76e-01 | 3.87e-01 | 5.05e-01 | 1.85e-01 | 2.52e-01 |
| TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX | 29 | 5.62e-01 | 6.39e-01 | 0.1740 | 0.039900 | 0.011500 | -0.144000 | 7.71e-02 | -4.23e-02 | 7.10e-01 | 9.15e-01 | 1.78e-01 | 4.72e-01 | 6.93e-01 |
| NERVOUS SYSTEM DEVELOPMENT | 537 | 1.01e-08 | 1.39e-07 | 0.1740 | -0.081800 | -0.076400 | 0.044500 | 8.54e-03 | -1.25e-01 | 1.25e-03 | 2.58e-03 | 7.88e-02 | 7.36e-01 | 7.61e-07 |
| VESICLE MEDIATED TRANSPORT | 596 | 5.73e-11 | 1.10e-09 | 0.1740 | 0.004450 | -0.023800 | 0.051600 | -4.00e-02 | 1.59e-01 | 8.54e-01 | 3.23e-01 | 3.23e-02 | 9.74e-02 | 3.87e-11 |
| METABOLISM OF STEROIDS | 110 | 6.67e-02 | 1.29e-01 | 0.1740 | -0.098100 | -0.065700 | -0.050100 | -8.90e-02 | 7.61e-02 | 7.56e-02 | 2.35e-01 | 3.65e-01 | 1.07e-01 | 1.69e-01 |
| INTRACELLULAR SIGNALING BY SECOND MESSENGERS | 274 | 3.10e-04 | 1.58e-03 | 0.1740 | 0.025900 | -0.140000 | 0.026000 | -7.25e-02 | 6.36e-02 | 4.62e-01 | 7.21e-05 | 4.60e-01 | 3.94e-02 | 7.07e-02 |
| TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY | 29 | 6.86e-01 | 7.36e-01 | 0.1730 | 0.081300 | -0.148000 | 0.028600 | -1.24e-02 | -2.56e-02 | 4.49e-01 | 1.68e-01 | 7.90e-01 | 9.08e-01 | 8.11e-01 |
| POTENTIAL THERAPEUTICS FOR SARS | 76 | 3.47e-01 | 4.44e-01 | 0.1730 | -0.047100 | -0.081500 | -0.003730 | -8.36e-02 | -1.19e-01 | 4.78e-01 | 2.20e-01 | 9.55e-01 | 2.08e-01 | 7.28e-02 |
| JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | 22 | 8.65e-01 | 8.88e-01 | 0.1730 | 0.135000 | -0.023200 | -0.022300 | -8.24e-02 | 6.28e-02 | 2.74e-01 | 8.51e-01 | 8.57e-01 | 5.03e-01 | 6.10e-01 |
| TRANSCRIPTIONAL REGULATION BY SMALL RNAS | 59 | 3.64e-01 | 4.61e-01 | 0.1730 | -0.077800 | -0.039800 | -0.012700 | 1.33e-01 | -6.59e-02 | 3.02e-01 | 5.97e-01 | 8.66e-01 | 7.70e-02 | 3.82e-01 |
| REGULATION OF TNFR1 SIGNALING | 34 | 6.48e-01 | 7.07e-01 | 0.1720 | 0.022200 | -0.166000 | 0.010400 | -1.38e-02 | -3.87e-02 | 8.23e-01 | 9.48e-02 | 9.17e-01 | 8.89e-01 | 6.97e-01 |
| ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | 23 | 6.28e-01 | 6.93e-01 | 0.1720 | 0.115000 | -0.073000 | -0.099400 | 3.16e-02 | -1.88e-02 | 3.41e-01 | 5.45e-01 | 4.09e-01 | 7.93e-01 | 8.76e-01 |
| METABOLISM OF FAT SOLUBLE VITAMINS | 30 | 6.05e-01 | 6.73e-01 | 0.1720 | 0.086200 | 0.134000 | -0.036600 | 1.08e-02 | -5.35e-02 | 4.14e-01 | 2.06e-01 | 7.29e-01 | 9.18e-01 | 6.12e-01 |
| TNF SIGNALING | 43 | 6.54e-01 | 7.10e-01 | 0.1710 | 0.016600 | -0.152000 | 0.006770 | -7.09e-02 | -3.09e-02 | 8.51e-01 | 8.48e-02 | 9.39e-01 | 4.22e-01 | 7.26e-01 |
| ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION | 105 | 1.01e-01 | 1.78e-01 | 0.1710 | -0.048800 | -0.068100 | 0.014300 | -1.49e-01 | 3.16e-03 | 3.88e-01 | 2.28e-01 | 8.01e-01 | 8.59e-03 | 9.55e-01 |
| LYSOSOME VESICLE BIOGENESIS | 32 | 6.49e-01 | 7.08e-01 | 0.1710 | -0.097800 | 0.056100 | 0.070600 | 9.19e-02 | 5.60e-02 | 3.38e-01 | 5.83e-01 | 4.89e-01 | 3.68e-01 | 5.84e-01 |
| SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 | 620 | 3.19e-08 | 3.95e-07 | 0.1700 | 0.009000 | -0.069800 | -0.017800 | -1.39e-01 | 6.48e-02 | 7.04e-01 | 3.15e-03 | 4.52e-01 | 4.33e-09 | 6.11e-03 |
| HCMV LATE EVENTS | 63 | 2.08e-01 | 3.02e-01 | 0.1690 | -0.074700 | -0.031300 | 0.021300 | 1.39e-01 | 4.77e-02 | 3.05e-01 | 6.67e-01 | 7.70e-01 | 5.67e-02 | 5.13e-01 |
| DISORDERS OF TRANSMEMBRANE TRANSPORTERS | 132 | 1.13e-02 | 3.21e-02 | 0.1690 | -0.055000 | -0.037500 | 0.036700 | 1.47e-01 | 3.23e-02 | 2.76e-01 | 4.58e-01 | 4.67e-01 | 3.54e-03 | 5.22e-01 |
| SEMA4D IN SEMAPHORIN SIGNALING | 24 | 7.76e-01 | 8.20e-01 | 0.1670 | 0.046700 | -0.065900 | -0.121000 | -1.90e-02 | -8.09e-02 | 6.92e-01 | 5.77e-01 | 3.05e-01 | 8.72e-01 | 4.93e-01 |
| CYTOKINE SIGNALING IN IMMUNE SYSTEM | 528 | 2.29e-07 | 2.52e-06 | 0.1670 | -0.052200 | -0.112000 | -0.113000 | -4.67e-03 | 3.84e-03 | 4.10e-02 | 1.22e-05 | 9.89e-06 | 8.55e-01 | 8.80e-01 |
| KINESINS | 48 | 5.08e-01 | 5.94e-01 | 0.1670 | 0.008540 | -0.027100 | 0.026600 | -1.61e-01 | 2.54e-02 | 9.18e-01 | 7.46e-01 | 7.50e-01 | 5.43e-02 | 7.60e-01 |
| TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | 32 | 8.52e-01 | 8.77e-01 | 0.1670 | -0.132000 | -0.070500 | -0.053200 | -2.75e-02 | -4.33e-02 | 1.96e-01 | 4.90e-01 | 6.02e-01 | 7.88e-01 | 6.72e-01 |
| G ALPHA I SIGNALLING EVENTS | 184 | 6.30e-03 | 1.98e-02 | 0.1670 | -0.007140 | -0.074800 | 0.072200 | -1.28e-01 | 2.22e-02 | 8.68e-01 | 8.06e-02 | 9.19e-02 | 2.76e-03 | 6.04e-01 |
| EGFR DOWNREGULATION | 27 | 6.62e-01 | 7.15e-01 | 0.1660 | -0.059900 | -0.008850 | 0.121000 | -5.41e-02 | -7.99e-02 | 5.90e-01 | 9.37e-01 | 2.75e-01 | 6.27e-01 | 4.72e-01 |
| MITOTIC SPINDLE CHECKPOINT | 96 | 3.16e-02 | 7.23e-02 | 0.1660 | -0.108000 | -0.077200 | 0.023500 | 4.14e-02 | 8.72e-02 | 6.65e-02 | 1.91e-01 | 6.91e-01 | 4.84e-01 | 1.40e-01 |
| DNA DOUBLE STRAND BREAK RESPONSE | 50 | 6.82e-01 | 7.33e-01 | 0.1660 | -0.096800 | 0.010200 | -0.037100 | 7.95e-02 | -1.01e-01 | 2.37e-01 | 9.00e-01 | 6.50e-01 | 3.31e-01 | 2.15e-01 |
| CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION | 337 | 7.62e-08 | 9.04e-07 | 0.1650 | -0.099700 | -0.049400 | 0.020000 | 6.54e-02 | 1.01e-01 | 1.71e-03 | 1.20e-01 | 5.28e-01 | 3.96e-02 | 1.46e-03 |
| RHO GTPASES ACTIVATE IQGAPS | 23 | 7.48e-01 | 7.94e-01 | 0.1650 | -0.104000 | -0.026900 | 0.092500 | 8.02e-02 | 2.29e-02 | 3.86e-01 | 8.23e-01 | 4.42e-01 | 5.06e-01 | 8.49e-01 |
| VISUAL PHOTOTRANSDUCTION | 54 | 3.02e-01 | 3.96e-01 | 0.1650 | 0.073400 | 0.139000 | -0.011800 | -3.36e-02 | -3.24e-02 | 3.51e-01 | 7.68e-02 | 8.81e-01 | 6.70e-01 | 6.81e-01 |
| ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION | 81 | 8.85e-02 | 1.61e-01 | 0.1640 | -0.053200 | -0.007640 | 0.071700 | -1.32e-01 | -3.86e-02 | 4.08e-01 | 9.06e-01 | 2.65e-01 | 3.95e-02 | 5.49e-01 |
| TRANS GOLGI NETWORK VESICLE BUDDING | 69 | 1.61e-01 | 2.50e-01 | 0.1640 | -0.099100 | -0.003850 | -0.009330 | -5.75e-03 | 1.30e-01 | 1.55e-01 | 9.56e-01 | 8.93e-01 | 9.34e-01 | 6.22e-02 |
| M PHASE | 336 | 3.90e-06 | 3.16e-05 | 0.1640 | -0.096600 | -0.007270 | 0.043000 | 1.21e-01 | 2.99e-02 | 2.41e-03 | 8.19e-01 | 1.77e-01 | 1.41e-04 | 3.48e-01 |
| INFECTION WITH MYCOBACTERIUM TUBERCULOSIS | 25 | 8.90e-01 | 9.09e-01 | 0.1630 | -0.095300 | -0.005250 | -0.119000 | 5.44e-02 | -1.62e-02 | 4.09e-01 | 9.64e-01 | 3.02e-01 | 6.38e-01 | 8.88e-01 |
| CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION | 20 | 9.27e-01 | 9.38e-01 | 0.1620 | -0.099300 | -0.089700 | -0.024100 | -8.80e-02 | -1.88e-04 | 4.42e-01 | 4.88e-01 | 8.52e-01 | 4.96e-01 | 9.99e-01 |
| TELOMERE EXTENSION BY TELOMERASE | 21 | 9.05e-01 | 9.20e-01 | 0.1610 | -0.053200 | -0.018900 | 0.008320 | 1.13e-01 | -9.96e-02 | 6.73e-01 | 8.81e-01 | 9.47e-01 | 3.68e-01 | 4.30e-01 |
| ACTIVATION OF BH3 ONLY PROTEINS | 30 | 7.91e-01 | 8.30e-01 | 0.1610 | -0.009110 | 0.009000 | 0.138000 | 7.99e-02 | 1.26e-02 | 9.31e-01 | 9.32e-01 | 1.90e-01 | 4.49e-01 | 9.05e-01 |
| BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS | 31 | 7.18e-01 | 7.64e-01 | 0.1610 | 0.004220 | 0.018000 | -0.155000 | -5.47e-03 | -3.76e-02 | 9.68e-01 | 8.63e-01 | 1.35e-01 | 9.58e-01 | 7.17e-01 |
| SIGNALING BY NUCLEAR RECEPTORS | 215 | 5.69e-02 | 1.15e-01 | 0.1600 | -0.090300 | -0.037200 | -0.115000 | -4.14e-02 | -3.23e-02 | 2.27e-02 | 3.48e-01 | 3.82e-03 | 2.96e-01 | 4.15e-01 |
| SENSORY PERCEPTION | 133 | 1.65e-02 | 4.32e-02 | 0.1590 | 0.121000 | 0.058200 | -0.008490 | -7.63e-02 | -3.79e-02 | 1.65e-02 | 2.47e-01 | 8.66e-01 | 1.29e-01 | 4.51e-01 |
| RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | 85 | 2.57e-01 | 3.54e-01 | 0.1580 | -0.009160 | 0.065500 | 0.125000 | 1.94e-02 | 6.83e-02 | 8.84e-01 | 2.97e-01 | 4.64e-02 | 7.57e-01 | 2.77e-01 |
| HOMOLOGY DIRECTED REPAIR | 103 | 2.33e-01 | 3.29e-01 | 0.1580 | -0.076700 | -0.019300 | -0.045600 | 1.07e-01 | -7.18e-02 | 1.79e-01 | 7.35e-01 | 4.24e-01 | 6.13e-02 | 2.08e-01 |
| SARS COV 2 INFECTION | 65 | 1.97e-01 | 2.89e-01 | 0.1570 | -0.099000 | -0.061200 | 0.102000 | 2.38e-02 | 4.42e-03 | 1.68e-01 | 3.94e-01 | 1.56e-01 | 7.40e-01 | 9.51e-01 |
| COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 86 | 2.41e-01 | 3.39e-01 | 0.1560 | -0.001750 | 0.033600 | 0.107000 | -1.07e-02 | 1.08e-01 | 9.78e-01 | 5.91e-01 | 8.74e-02 | 8.64e-01 | 8.27e-02 |
| TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX | 14 | 9.12e-01 | 9.24e-01 | 0.1560 | 0.059300 | 0.014600 | -0.067900 | 1.25e-01 | -1.67e-02 | 7.01e-01 | 9.25e-01 | 6.60e-01 | 4.18e-01 | 9.14e-01 |
| REGULATION OF LIPID METABOLISM BY PPARALPHA | 105 | 2.22e-01 | 3.16e-01 | 0.1560 | 0.054500 | -0.087800 | 0.081500 | -8.30e-02 | 7.18e-03 | 3.35e-01 | 1.20e-01 | 1.49e-01 | 1.42e-01 | 8.99e-01 |
| SIGNALING BY RECEPTOR TYROSINE KINASES | 449 | 8.65e-05 | 5.06e-04 | 0.1560 | 0.013100 | -0.083500 | -0.002390 | -1.18e-01 | 5.64e-02 | 6.36e-01 | 2.53e-03 | 9.31e-01 | 2.00e-05 | 4.12e-02 |
| AURKA ACTIVATION BY TPX2 | 71 | 4.32e-01 | 5.25e-01 | 0.1540 | -0.010600 | 0.055900 | 0.097100 | 4.09e-02 | 9.66e-02 | 8.77e-01 | 4.16e-01 | 1.57e-01 | 5.52e-01 | 1.59e-01 |
| RESOLUTION OF SISTER CHROMATID COHESION | 100 | 6.61e-02 | 1.28e-01 | 0.1540 | -0.083800 | -0.077400 | 0.002790 | 8.02e-03 | 1.03e-01 | 1.48e-01 | 1.81e-01 | 9.62e-01 | 8.90e-01 | 7.57e-02 |
| MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION | 16 | 9.69e-01 | 9.74e-01 | 0.1530 | 0.081400 | 0.050000 | 0.020500 | -5.72e-02 | 1.04e-01 | 5.73e-01 | 7.29e-01 | 8.87e-01 | 6.92e-01 | 4.74e-01 |
| DISEASES OF METABOLISM | 194 | 8.03e-02 | 1.49e-01 | 0.1530 | 0.027300 | 0.107000 | 0.040700 | 4.61e-02 | 8.63e-02 | 5.12e-01 | 1.03e-02 | 3.29e-01 | 2.69e-01 | 3.86e-02 |
| PLASMA LIPOPROTEIN CLEARANCE | 25 | 7.56e-01 | 8.02e-01 | 0.1510 | -0.130000 | 0.027600 | 0.004160 | -5.63e-02 | 4.55e-02 | 2.61e-01 | 8.11e-01 | 9.71e-01 | 6.26e-01 | 6.93e-01 |
| FLT3 SIGNALING | 36 | 7.91e-01 | 8.30e-01 | 0.1510 | 0.023200 | -0.098000 | 0.013900 | -5.83e-02 | 9.48e-02 | 8.10e-01 | 3.09e-01 | 8.86e-01 | 5.45e-01 | 3.25e-01 |
| HDR THROUGH HOMOLOGOUS RECOMBINATION HRR | 62 | 5.98e-01 | 6.67e-01 | 0.1490 | -0.034200 | 0.041000 | -0.028200 | 1.14e-01 | -7.48e-02 | 6.42e-01 | 5.77e-01 | 7.01e-01 | 1.20e-01 | 3.09e-01 |
| METABOLISM OF LIPIDS | 600 | 2.68e-08 | 3.39e-07 | 0.1490 | 0.013300 | 0.003830 | -0.019000 | 3.20e-02 | 1.44e-01 | 5.80e-01 | 8.73e-01 | 4.28e-01 | 1.83e-01 | 2.09e-09 |
| LEISHMANIA INFECTION | 183 | 3.79e-02 | 8.41e-02 | 0.1490 | -0.023300 | -0.060300 | 0.011700 | -1.27e-01 | 4.17e-02 | 5.87e-01 | 1.60e-01 | 7.84e-01 | 3.08e-03 | 3.32e-01 |
| CELL CYCLE MITOTIC | 468 | 8.42e-07 | 8.22e-06 | 0.1480 | -0.082800 | -0.004240 | 0.024200 | 1.17e-01 | 2.92e-02 | 2.23e-03 | 8.76e-01 | 3.71e-01 | 1.61e-05 | 2.80e-01 |
| FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | 119 | 1.72e-01 | 2.62e-01 | 0.1480 | 0.015100 | -0.005820 | 0.012200 | -9.38e-02 | 1.12e-01 | 7.77e-01 | 9.13e-01 | 8.19e-01 | 7.74e-02 | 3.46e-02 |
| DEUBIQUITINATION | 237 | 3.99e-03 | 1.38e-02 | 0.1470 | -0.078400 | -0.110000 | -0.047800 | 3.21e-02 | 1.33e-02 | 3.79e-02 | 3.70e-03 | 2.06e-01 | 3.96e-01 | 7.25e-01 |
| SIGNALING BY FGFR4 | 31 | 8.96e-01 | 9.11e-01 | 0.1470 | -0.024700 | -0.105000 | -0.067900 | -6.20e-02 | 3.86e-02 | 8.12e-01 | 3.14e-01 | 5.13e-01 | 5.50e-01 | 7.10e-01 |
| MITOTIC PROPHASE | 91 | 2.08e-01 | 3.02e-01 | 0.1450 | 0.018900 | -0.038000 | 0.012000 | 5.37e-02 | 1.27e-01 | 7.55e-01 | 5.31e-01 | 8.43e-01 | 3.76e-01 | 3.64e-02 |
| RHO GTPASES ACTIVATE FORMINS | 117 | 5.28e-02 | 1.07e-01 | 0.1440 | -0.086000 | -0.082500 | 0.031900 | 2.29e-03 | 7.38e-02 | 1.08e-01 | 1.24e-01 | 5.51e-01 | 9.66e-01 | 1.68e-01 |
| INNATE IMMUNE SYSTEM | 760 | 1.19e-10 | 2.15e-09 | 0.1440 | -0.057200 | -0.030200 | -0.096400 | 7.10e-02 | 4.58e-02 | 7.65e-03 | 1.59e-01 | 6.96e-06 | 9.43e-04 | 3.30e-02 |
| FLT3 SIGNALING IN DISEASE | 27 | 8.59e-01 | 8.83e-01 | 0.1430 | 0.021100 | -0.093900 | -0.033800 | -1.83e-02 | 9.86e-02 | 8.49e-01 | 3.98e-01 | 7.61e-01 | 8.69e-01 | 3.75e-01 |
| SIGNALING BY FGFR IN DISEASE | 53 | 7.95e-01 | 8.33e-01 | 0.1420 | -0.057100 | -0.090000 | -0.061500 | 5.10e-03 | -7.13e-02 | 4.72e-01 | 2.57e-01 | 4.39e-01 | 9.49e-01 | 3.70e-01 |
| GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION | 38 | 8.72e-01 | 8.92e-01 | 0.1420 | -0.063200 | -0.094500 | -0.006740 | -8.06e-02 | -2.65e-02 | 5.00e-01 | 3.13e-01 | 9.43e-01 | 3.90e-01 | 7.77e-01 |
| PEPTIDE HORMONE METABOLISM | 56 | 6.68e-01 | 7.20e-01 | 0.1410 | -0.102000 | -0.063300 | -0.012900 | -7.25e-02 | -8.99e-03 | 1.87e-01 | 4.13e-01 | 8.67e-01 | 3.48e-01 | 9.07e-01 |
| REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION | 86 | 4.37e-01 | 5.29e-01 | 0.1410 | -0.059800 | -0.074400 | -0.014200 | 5.83e-02 | -8.43e-02 | 3.38e-01 | 2.34e-01 | 8.20e-01 | 3.50e-01 | 1.77e-01 |
| RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | 102 | 2.90e-01 | 3.85e-01 | 0.1400 | -0.003280 | 0.092700 | -0.072800 | 7.52e-02 | -2.72e-03 | 9.54e-01 | 1.06e-01 | 2.04e-01 | 1.90e-01 | 9.62e-01 |
| SIGNALING BY INTERLEUKINS | 337 | 1.07e-04 | 6.12e-04 | 0.1390 | -0.034200 | -0.071600 | -0.089500 | 4.52e-02 | 5.49e-02 | 2.82e-01 | 2.43e-02 | 4.86e-03 | 1.55e-01 | 8.40e-02 |
| NEGATIVE REGULATION OF FGFR4 SIGNALING | 21 | 9.63e-01 | 9.68e-01 | 0.1380 | 0.067400 | -0.012900 | 0.051200 | 2.11e-02 | 1.07e-01 | 5.93e-01 | 9.19e-01 | 6.85e-01 | 8.67e-01 | 3.97e-01 |
| HCMV INFECTION | 101 | 1.53e-01 | 2.41e-01 | 0.1380 | -0.068600 | -0.069200 | 0.048900 | 8.48e-02 | -3.25e-03 | 2.34e-01 | 2.30e-01 | 3.96e-01 | 1.41e-01 | 9.55e-01 |
| CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA | 59 | 5.27e-01 | 6.09e-01 | 0.1380 | -0.017400 | -0.021800 | -0.091100 | 9.23e-02 | -3.65e-02 | 8.18e-01 | 7.73e-01 | 2.26e-01 | 2.20e-01 | 6.28e-01 |
| TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | 73 | 5.80e-01 | 6.54e-01 | 0.1380 | 0.042000 | -0.066400 | 0.067400 | -9.00e-02 | 1.01e-02 | 5.35e-01 | 3.27e-01 | 3.20e-01 | 1.84e-01 | 8.82e-01 |
| SARS COV INFECTIONS | 139 | 1.44e-01 | 2.29e-01 | 0.1370 | -0.085000 | -0.072400 | 0.039000 | -2.90e-02 | -6.33e-02 | 8.40e-02 | 1.41e-01 | 4.28e-01 | 5.55e-01 | 1.98e-01 |
| SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | 20 | 8.91e-01 | 9.09e-01 | 0.1350 | 0.052400 | 0.028900 | -0.103000 | 3.37e-03 | -6.43e-02 | 6.85e-01 | 8.23e-01 | 4.26e-01 | 9.79e-01 | 6.19e-01 |
| CELL CYCLE | 583 | 2.44e-06 | 2.13e-05 | 0.1340 | -0.073500 | -0.010600 | 0.021700 | 1.09e-01 | -7.67e-03 | 2.55e-03 | 6.64e-01 | 3.73e-01 | 7.60e-06 | 7.53e-01 |
| HCMV EARLY EVENTS | 78 | 5.15e-01 | 6.02e-01 | 0.1340 | -0.058600 | -0.119000 | -0.005320 | -4.81e-03 | -1.82e-02 | 3.71e-01 | 7.01e-02 | 9.35e-01 | 9.41e-01 | 7.82e-01 |
| CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | 88 | 2.98e-01 | 3.94e-01 | 0.1330 | 0.026300 | 0.069100 | -0.093100 | -4.79e-02 | 3.65e-02 | 6.70e-01 | 2.63e-01 | 1.32e-01 | 4.38e-01 | 5.55e-01 |
| SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS | 73 | 6.62e-01 | 7.15e-01 | 0.1320 | 0.001420 | -0.087900 | 0.024500 | -9.45e-02 | -1.61e-02 | 9.83e-01 | 1.94e-01 | 7.18e-01 | 1.63e-01 | 8.12e-01 |
| HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE | 40 | 8.73e-01 | 8.93e-01 | 0.1300 | -0.039600 | 0.012900 | -0.109000 | 1.50e-02 | -5.42e-02 | 6.65e-01 | 8.88e-01 | 2.31e-01 | 8.70e-01 | 5.54e-01 |
| DEVELOPMENTAL BIOLOGY | 787 | 5.52e-07 | 5.58e-06 | 0.1300 | -0.050800 | -0.060700 | 0.037100 | -2.21e-02 | -9.31e-02 | 1.61e-02 | 4.04e-03 | 7.86e-02 | 2.96e-01 | 1.03e-05 |
| CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS | 88 | 5.95e-01 | 6.66e-01 | 0.1290 | 0.046200 | -0.010200 | 0.046100 | -7.05e-02 | 8.55e-02 | 4.54e-01 | 8.69e-01 | 4.55e-01 | 2.53e-01 | 1.66e-01 |
| FOXO MEDIATED TRANSCRIPTION | 56 | 5.70e-01 | 6.45e-01 | 0.1270 | -0.021600 | -0.111000 | -0.016200 | 2.60e-02 | 4.96e-02 | 7.80e-01 | 1.50e-01 | 8.34e-01 | 7.36e-01 | 5.21e-01 |
| TRANSCRIPTIONAL REGULATION BY TP53 | 339 | 1.42e-03 | 5.75e-03 | 0.1260 | -0.053100 | -0.027800 | 0.042500 | 1.02e-01 | -1.43e-03 | 9.37e-02 | 3.81e-01 | 1.80e-01 | 1.29e-03 | 9.64e-01 |
| DNA DOUBLE STRAND BREAK REPAIR | 132 | 2.76e-01 | 3.73e-01 | 0.1250 | -0.039500 | -0.018500 | -0.019200 | 1.00e-01 | -5.80e-02 | 4.34e-01 | 7.13e-01 | 7.04e-01 | 4.66e-02 | 2.50e-01 |
| SIGNALING BY MET | 74 | 7.20e-01 | 7.66e-01 | 0.1240 | -0.028900 | -0.052600 | -0.030800 | -9.80e-02 | 3.41e-02 | 6.68e-01 | 4.34e-01 | 6.47e-01 | 1.45e-01 | 6.12e-01 |
| NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 12 | 9.90e-01 | 9.90e-01 | 0.1210 | -0.030600 | 0.103000 | 0.013000 | 3.05e-02 | -4.51e-02 | 8.55e-01 | 5.38e-01 | 9.38e-01 | 8.55e-01 | 7.87e-01 |
| REGULATION OF TP53 ACTIVITY | 148 | 1.74e-01 | 2.64e-01 | 0.1210 | 0.027000 | -0.106000 | 0.037500 | -5.26e-03 | 3.48e-02 | 5.71e-01 | 2.64e-02 | 4.31e-01 | 9.12e-01 | 4.66e-01 |
| ACYL CHAIN REMODELLING OF PE | 16 | 9.61e-01 | 9.68e-01 | 0.1200 | -0.040000 | -0.004430 | 0.059700 | -6.38e-02 | 7.14e-02 | 7.82e-01 | 9.76e-01 | 6.79e-01 | 6.59e-01 | 6.21e-01 |
| INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | 13 | 9.80e-01 | 9.82e-01 | 0.1190 | -0.099200 | -0.037100 | -0.015700 | 6.09e-03 | 5.25e-02 | 5.36e-01 | 8.17e-01 | 9.22e-01 | 9.70e-01 | 7.43e-01 |
| TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS | 28 | 8.92e-01 | 9.09e-01 | 0.1180 | -0.111000 | -0.008190 | 0.034500 | -1.60e-02 | -1.52e-02 | 3.10e-01 | 9.40e-01 | 7.52e-01 | 8.84e-01 | 8.89e-01 |
| RESPONSE OF MTB TO PHAGOCYTOSIS | 22 | 9.78e-01 | 9.81e-01 | 0.1160 | -0.106000 | -0.021800 | -0.018400 | 5.52e-03 | -3.62e-02 | 3.87e-01 | 8.59e-01 | 8.81e-01 | 9.64e-01 | 7.69e-01 |
| ADAPTIVE IMMUNE SYSTEM | 585 | 4.68e-06 | 3.71e-05 | 0.1140 | -0.042700 | -0.036700 | 0.005640 | 3.12e-02 | 9.40e-02 | 7.90e-02 | 1.31e-01 | 8.17e-01 | 1.99e-01 | 1.10e-04 |
| HATS ACETYLATE HISTONES | 90 | 5.63e-01 | 6.40e-01 | 0.1110 | 0.011900 | -0.073200 | 0.077800 | -7.26e-03 | -2.82e-02 | 8.45e-01 | 2.30e-01 | 2.03e-01 | 9.05e-01 | 6.44e-01 |
| NEGATIVE REGULATION OF MET ACTIVITY | 20 | 9.88e-01 | 9.89e-01 | 0.1090 | 0.008960 | -0.094400 | -0.011400 | -4.46e-02 | -2.73e-02 | 9.45e-01 | 4.65e-01 | 9.30e-01 | 7.30e-01 | 8.32e-01 |
| G ALPHA Q SIGNALLING EVENTS | 140 | 4.92e-01 | 5.80e-01 | 0.1070 | -0.005610 | -0.056400 | 0.022900 | -8.55e-02 | 1.73e-02 | 9.09e-01 | 2.50e-01 | 6.40e-01 | 8.12e-02 | 7.25e-01 |
| CILIUM ASSEMBLY | 189 | 9.91e-02 | 1.76e-01 | 0.1060 | -0.075800 | 0.015200 | 0.045600 | -3.04e-02 | -4.82e-02 | 7.27e-02 | 7.19e-01 | 2.81e-01 | 4.71e-01 | 2.54e-01 |
| RHOH GTPASE CYCLE | 37 | 8.95e-01 | 9.10e-01 | 0.1060 | 0.012200 | 0.038900 | -0.084900 | -2.85e-02 | -3.85e-02 | 8.98e-01 | 6.82e-01 | 3.72e-01 | 7.64e-01 | 6.86e-01 |
| HDR THROUGH SINGLE STRAND ANNEALING SSA | 36 | 9.34e-01 | 9.43e-01 | 0.1050 | -0.003690 | 0.027100 | -0.053700 | 4.70e-02 | -7.22e-02 | 9.69e-01 | 7.79e-01 | 5.77e-01 | 6.25e-01 | 4.53e-01 |
| RNA POLYMERASE II TRANSCRIPTION | 1069 | 5.82e-05 | 3.53e-04 | 0.1040 | -0.054900 | -0.078100 | -0.004530 | -1.83e-02 | -3.55e-02 | 2.69e-03 | 1.95e-05 | 8.04e-01 | 3.16e-01 | 5.23e-02 |
| SIGNALING BY FGFR3 | 34 | 9.71e-01 | 9.74e-01 | 0.1010 | -0.001750 | -0.074200 | -0.046000 | -4.13e-02 | 2.80e-02 | 9.86e-01 | 4.54e-01 | 6.43e-01 | 6.77e-01 | 7.78e-01 |
| MITOTIC PROMETAPHASE | 175 | 1.97e-01 | 2.89e-01 | 0.0989 | -0.035500 | -0.012800 | 0.041600 | -6.18e-03 | 8.11e-02 | 4.18e-01 | 7.71e-01 | 3.43e-01 | 8.88e-01 | 6.46e-02 |
| HEMOSTASIS | 463 | 3.19e-02 | 7.28e-02 | 0.0979 | 0.028100 | 0.011300 | -0.011900 | -5.35e-02 | 7.53e-02 | 3.01e-01 | 6.78e-01 | 6.62e-01 | 4.96e-02 | 5.70e-03 |
| POST TRANSLATIONAL PROTEIN MODIFICATION | 1184 | 3.21e-07 | 3.39e-06 | 0.0969 | -0.006020 | -0.015400 | 0.029200 | 2.58e-02 | 8.72e-02 | 7.30e-01 | 3.77e-01 | 9.44e-02 | 1.38e-01 | 5.66e-07 |
| ORGANELLE BIOGENESIS AND MAINTENANCE | 281 | 1.38e-01 | 2.23e-01 | 0.0920 | -0.043100 | -0.045500 | 0.042400 | 3.04e-02 | -4.25e-02 | 2.15e-01 | 1.90e-01 | 2.22e-01 | 3.82e-01 | 2.22e-01 |
| REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION | 84 | 8.52e-01 | 8.77e-01 | 0.0909 | -0.015900 | 0.037400 | 0.062900 | 4.09e-02 | 3.13e-02 | 8.02e-01 | 5.53e-01 | 3.20e-01 | 5.18e-01 | 6.20e-01 |
| ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE | 96 | 5.87e-01 | 6.61e-01 | 0.0889 | -0.051400 | 0.012800 | 0.053700 | -3.90e-02 | -2.63e-02 | 3.84e-01 | 8.28e-01 | 3.64e-01 | 5.09e-01 | 6.56e-01 |
| CELLULAR SENESCENCE | 138 | 8.38e-01 | 8.67e-01 | 0.0879 | -0.040100 | -0.037600 | -0.033300 | -7.44e-03 | -5.95e-02 | 4.17e-01 | 4.46e-01 | 5.00e-01 | 8.80e-01 | 2.28e-01 |
| RHO GTPASE EFFECTORS | 243 | 2.55e-01 | 3.53e-01 | 0.0790 | -0.028200 | -0.040000 | 0.022200 | -1.32e-03 | 5.79e-02 | 4.49e-01 | 2.84e-01 | 5.51e-01 | 9.72e-01 | 1.21e-01 |
| PLATELET ACTIVATION SIGNALING AND AGGREGATION | 216 | 5.22e-01 | 6.06e-01 | 0.0737 | -0.013100 | -0.021400 | -0.027400 | -7.26e-03 | 6.32e-02 | 7.40e-01 | 5.88e-01 | 4.88e-01 | 8.54e-01 | 1.10e-01 |
Detailed Gene set reports
EUKARYOTIC TRANSLATION ELONGATION
| metric | value |
|---|---|
| setSize | 87 |
| pMANOVA | 4.25e-70 |
| p.adjustMANOVA | 2.45e-67 |
| s.dist | 1.23 |
| s.hyp | -0.512 |
| s.hip | 0.137 |
| s.amy | -0.204 |
| s.pag | 0.857 |
| s.ni | -0.678 |
| p.hyp | 1.54e-16 |
| p.hip | 0.0273 |
| p.amy | 0.00102 |
| p.pag | 1.2e-43 |
| p.ni | 7.01e-28 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | ni |
|---|---|---|
| Rps29 | 7482 | -7465 |
| Rpl38 | 7427 | -7458 |
| Rps28 | 7397 | -7470 |
| Rpl39 | 7435 | -7398 |
| Rps27 | 7449 | -7364 |
| Rps21 | 7488 | -7191 |
| Rpl37a | 7353 | -7233 |
| Rpl37 | 7169 | -7308 |
| Rpl23 | 6983 | -7403 |
| Rpl35a | 7450 | -6779 |
| Rpl36al | 7142 | -7041 |
| Rpl35 | 7203 | -6944 |
| Rps23 | 6890 | -7067 |
| Rps17 | 7182 | -6746 |
| Rpl36a | 6846 | -6933 |
| Rps8 | 7004 | -6741 |
| Rpl30 | 6489 | -7269 |
| Rpl21 | 6613 | -7105 |
| Rpl31 | 7055 | -6596 |
| Rpl36 | 7394 | -6244 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Eef1a1 | -4411 | 2294 | -379 | 5219 | -1585 |
| Eef1a2 | -2588 | 1169 | 4877 | 143 | 6668 |
| Eef1b2 | -4710 | 2420 | 473 | 6170 | -4981 |
| Eef1d | -3728 | 5506 | -4520 | 6179 | -1242 |
| Eef1g | -4818 | -581 | -3602 | 5481 | -4562 |
| Eef2 | 3372 | 350 | -1855 | 1302 | 5577 |
| Fau | -5907 | 1583 | 1608 | 7212 | -5383 |
| Rpl10 | 7552 | 2305 | -6483 | 1980 | 1798 |
| Rpl10a | -4754 | 5887 | -3904 | 6315 | -6264 |
| Rpl11 | -7040 | -1610 | -1752 | 7106 | -5100 |
| Rpl12 | -1293 | 111 | -1276 | 5593 | -4815 |
| Rpl13 | -5435 | 705 | -309 | 7111 | -4751 |
| Rpl13a | -6127 | -800 | -4926 | 6137 | -3678 |
| Rpl14 | -4973 | 3377 | -3827 | 6231 | -6184 |
| Rpl15 | -1081 | 4664 | -97 | 5670 | -5225 |
| Rpl17 | -6154 | 1812 | -4356 | 5972 | -3587 |
| Rpl18 | -3623 | 1407 | 1250 | 6814 | -5632 |
| Rpl18a | -1090 | 3984 | -5189 | 6777 | -4423 |
| Rpl19 | -6145 | 1844 | 1393 | 7139 | -5256 |
| Rpl21 | -5242 | 1494 | -2632 | 6613 | -7105 |
| Rpl22 | 2309 | 1493 | 135 | 7361 | -5393 |
| Rpl22l1 | -6274 | -4977 | -2367 | 6270 | -5683 |
| Rpl23 | -4886 | -1314 | -5284 | 6983 | -7403 |
| Rpl23a | -5685 | 181 | -4668 | 5986 | -6814 |
| Rpl24 | -6576 | 1391 | -3886 | 6934 | -6380 |
| Rpl26 | -6659 | 1690 | -587 | 7025 | -6436 |
| Rpl27 | -6845 | 1737 | -3419 | 6972 | -3911 |
| Rpl27a | -5517 | 3660 | -2513 | 5849 | -4735 |
| Rpl28 | -1279 | 5641 | -1248 | 5705 | -5460 |
| Rpl29 | -1125 | 4140 | -4187 | 6593 | -5922 |
| Rpl3 | -4393 | 97 | 1158 | 6008 | -4443 |
| Rpl30 | -3489 | -1769 | -4305 | 6489 | -7269 |
| Rpl31 | -6836 | -3203 | -1412 | 7055 | -6596 |
| Rpl32 | -4734 | -2231 | 1048 | 7325 | -5634 |
| Rpl34 | -5472 | -4039 | -1304 | 7052 | -5665 |
| Rpl35 | -5746 | -5044 | -3769 | 7203 | -6944 |
| Rpl35a | -5482 | -3840 | 570 | 7450 | -6779 |
| Rpl36 | -4150 | -526 | -925 | 7394 | -6244 |
| Rpl36a | -5737 | 966 | -3217 | 6846 | -6933 |
| Rpl36al | -5513 | 1911 | -471 | 7142 | -7041 |
| Rpl37 | -4803 | -2009 | -157 | 7169 | -7308 |
| Rpl37a | -5196 | -2693 | 70 | 7353 | -7233 |
| Rpl38 | -4285 | -3890 | 857 | 7427 | -7458 |
| Rpl39 | -6226 | -2451 | 1477 | 7435 | -7398 |
| Rpl4 | -4925 | 1852 | -4074 | 6135 | -4712 |
| Rpl5 | 5744 | -2476 | -3141 | 5665 | 42 |
| Rpl6 | -5411 | 5527 | -1164 | 5021 | -4217 |
| Rpl7 | -5113 | 1762 | 151 | 6242 | -4040 |
| Rpl7a | -3564 | 4076 | 1931 | 6938 | -2667 |
| Rpl8 | -3703 | 3543 | -3664 | 6481 | -4491 |
| Rpl9 | -5504 | 344 | 903 | 6756 | -2526 |
| Rplp0 | -3763 | 4412 | -942 | 6357 | 956 |
| Rplp1 | -3659 | -3603 | -814 | 6990 | -6512 |
| Rplp2 | -1405 | 721 | 5081 | 7200 | -5799 |
| Rps10 | -5436 | 1596 | -1596 | 7118 | -2524 |
| Rps11 | -6088 | -966 | -1330 | 6240 | -6425 |
| Rps12 | -6536 | 2445 | -4827 | 7047 | -5574 |
| Rps13 | -2674 | -235 | -1978 | 6430 | -3919 |
| Rps14 | -3675 | 1734 | 3410 | 7146 | -3493 |
| Rps15 | -5634 | 2477 | 239 | 7130 | -5513 |
| Rps15a | 369 | 608 | -3369 | 6779 | -5204 |
| Rps16 | -4792 | 2799 | -1537 | 6267 | -5455 |
| Rps17 | -5260 | -1557 | 1246 | 7182 | -6746 |
| Rps18 | -4838 | 1158 | 194 | 6830 | -4753 |
| Rps19 | -6105 | -2857 | -5576 | 6611 | -5782 |
| Rps2 | -2017 | 387 | -812 | 6266 | -3726 |
| Rps20 | -4819 | -1197 | -4402 | 5625 | -7090 |
| Rps21 | -4549 | -3950 | -722 | 7488 | -7191 |
| Rps23 | -6959 | 2961 | -3533 | 6890 | -7067 |
| Rps24 | -6377 | -301 | -5394 | 5997 | -5015 |
| Rps25 | -6573 | -1150 | -1883 | 6238 | -5538 |
| Rps26 | -5325 | 3572 | -3697 | 5769 | -6007 |
| Rps27 | -5449 | -2098 | 2068 | 7449 | -7364 |
| Rps27a | -6372 | -7132 | -2043 | 6853 | -6401 |
| Rps27l | -4990 | -3246 | -4325 | 6048 | -3758 |
| Rps28 | -2854 | -2799 | 2837 | 7397 | -7470 |
| Rps29 | -234 | -4717 | -446 | 7482 | -7465 |
| Rps3 | -5535 | 1738 | -2705 | 6117 | -1500 |
| Rps3a1 | -6001 | 295 | -2164 | 5731 | -4251 |
| Rps4x | -3555 | -300 | -4680 | 5409 | -4453 |
| Rps5 | -4284 | 1344 | -1916 | 5993 | -4583 |
| Rps6 | -4272 | 4707 | 1599 | 6014 | -5295 |
| Rps7 | -5696 | 1849 | -3387 | 6808 | -5804 |
| Rps8 | -6704 | -566 | -5243 | 7004 | -6741 |
| Rps9 | -5004 | 1757 | -844 | 6794 | -4576 |
| Rpsa | -5034 | -2245 | -4844 | 5145 | -2970 |
| Uba52 | -2504 | 5042 | 585 | 6605 | -5655 |
RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY
| metric | value |
|---|---|
| setSize | 94 |
| pMANOVA | 8.77e-65 |
| p.adjustMANOVA | 2.53e-62 |
| s.dist | 1.14 |
| s.hyp | -0.487 |
| s.hip | 0.0738 |
| s.amy | -0.211 |
| s.pag | 0.762 |
| s.ni | -0.66 |
| p.hyp | 3.28e-16 |
| p.hip | 0.217 |
| p.amy | 0.000401 |
| p.pag | 1.89e-37 |
| p.ni | 1.8e-28 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | ni |
|---|---|---|
| Rps29 | 7482 | -7465 |
| Rpl38 | 7427 | -7458 |
| Rps28 | 7397 | -7470 |
| Rpl39 | 7435 | -7398 |
| Rps27 | 7449 | -7364 |
| Rps21 | 7488 | -7191 |
| Rpl37a | 7353 | -7233 |
| Rpl37 | 7169 | -7308 |
| Rpl23 | 6983 | -7403 |
| Rpl35a | 7450 | -6779 |
| Rpl36al | 7142 | -7041 |
| Rpl35 | 7203 | -6944 |
| Rps23 | 6890 | -7067 |
| Rps17 | 7182 | -6746 |
| Rpl36a | 6846 | -6933 |
| Rps8 | 7004 | -6741 |
| Rpl30 | 6489 | -7269 |
| Rpl21 | 6613 | -7105 |
| Rpl31 | 7055 | -6596 |
| Rpl36 | 7394 | -6244 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Asns | 3882 | -6268 | 3921 | -1608 | 3670 |
| Atf2 | -2259 | -2053 | -1225 | -6889 | 4100 |
| Atf3 | -7700 | -7800 | -7270 | 402 | -7377 |
| Atf4 | -5109 | -7556 | -3593 | 7029 | -2762 |
| Cebpb | 1867 | 5859 | 3905 | 1566 | 1301 |
| Cebpg | -5947 | -3335 | -491 | -484 | -5918 |
| Ddit3 | -8087 | -8557 | -6904 | 5070 | -7401 |
| Eif2ak4 | 6067 | 4810 | 662 | -4836 | -2491 |
| Eif2s1 | -6701 | -39 | -1217 | 5813 | 2921 |
| Eif2s2 | -4538 | -2403 | -5282 | 4050 | -5700 |
| Eif2s3x | 17 | -3878 | -3881 | -646 | 1396 |
| Fau | -5907 | 1583 | 1608 | 7212 | -5383 |
| Gcn1 | 6541 | -4336 | 5274 | -6548 | 2059 |
| Impact | -6033 | 2687 | -5811 | -5272 | -4307 |
| Rpl10 | 7552 | 2305 | -6483 | 1980 | 1798 |
| Rpl10a | -4754 | 5887 | -3904 | 6315 | -6264 |
| Rpl11 | -7040 | -1610 | -1752 | 7106 | -5100 |
| Rpl12 | -1293 | 111 | -1276 | 5593 | -4815 |
| Rpl13 | -5435 | 705 | -309 | 7111 | -4751 |
| Rpl13a | -6127 | -800 | -4926 | 6137 | -3678 |
| Rpl14 | -4973 | 3377 | -3827 | 6231 | -6184 |
| Rpl15 | -1081 | 4664 | -97 | 5670 | -5225 |
| Rpl17 | -6154 | 1812 | -4356 | 5972 | -3587 |
| Rpl18 | -3623 | 1407 | 1250 | 6814 | -5632 |
| Rpl18a | -1090 | 3984 | -5189 | 6777 | -4423 |
| Rpl19 | -6145 | 1844 | 1393 | 7139 | -5256 |
| Rpl21 | -5242 | 1494 | -2632 | 6613 | -7105 |
| Rpl22 | 2309 | 1493 | 135 | 7361 | -5393 |
| Rpl22l1 | -6274 | -4977 | -2367 | 6270 | -5683 |
| Rpl23 | -4886 | -1314 | -5284 | 6983 | -7403 |
| Rpl23a | -5685 | 181 | -4668 | 5986 | -6814 |
| Rpl24 | -6576 | 1391 | -3886 | 6934 | -6380 |
| Rpl26 | -6659 | 1690 | -587 | 7025 | -6436 |
| Rpl27 | -6845 | 1737 | -3419 | 6972 | -3911 |
| Rpl27a | -5517 | 3660 | -2513 | 5849 | -4735 |
| Rpl28 | -1279 | 5641 | -1248 | 5705 | -5460 |
| Rpl29 | -1125 | 4140 | -4187 | 6593 | -5922 |
| Rpl3 | -4393 | 97 | 1158 | 6008 | -4443 |
| Rpl30 | -3489 | -1769 | -4305 | 6489 | -7269 |
| Rpl31 | -6836 | -3203 | -1412 | 7055 | -6596 |
| Rpl32 | -4734 | -2231 | 1048 | 7325 | -5634 |
| Rpl34 | -5472 | -4039 | -1304 | 7052 | -5665 |
| Rpl35 | -5746 | -5044 | -3769 | 7203 | -6944 |
| Rpl35a | -5482 | -3840 | 570 | 7450 | -6779 |
| Rpl36 | -4150 | -526 | -925 | 7394 | -6244 |
| Rpl36a | -5737 | 966 | -3217 | 6846 | -6933 |
| Rpl36al | -5513 | 1911 | -471 | 7142 | -7041 |
| Rpl37 | -4803 | -2009 | -157 | 7169 | -7308 |
| Rpl37a | -5196 | -2693 | 70 | 7353 | -7233 |
| Rpl38 | -4285 | -3890 | 857 | 7427 | -7458 |
| Rpl39 | -6226 | -2451 | 1477 | 7435 | -7398 |
| Rpl4 | -4925 | 1852 | -4074 | 6135 | -4712 |
| Rpl5 | 5744 | -2476 | -3141 | 5665 | 42 |
| Rpl6 | -5411 | 5527 | -1164 | 5021 | -4217 |
| Rpl7 | -5113 | 1762 | 151 | 6242 | -4040 |
| Rpl7a | -3564 | 4076 | 1931 | 6938 | -2667 |
| Rpl8 | -3703 | 3543 | -3664 | 6481 | -4491 |
| Rpl9 | -5504 | 344 | 903 | 6756 | -2526 |
| Rplp0 | -3763 | 4412 | -942 | 6357 | 956 |
| Rplp1 | -3659 | -3603 | -814 | 6990 | -6512 |
| Rplp2 | -1405 | 721 | 5081 | 7200 | -5799 |
| Rps10 | -5436 | 1596 | -1596 | 7118 | -2524 |
| Rps11 | -6088 | -966 | -1330 | 6240 | -6425 |
| Rps12 | -6536 | 2445 | -4827 | 7047 | -5574 |
| Rps13 | -2674 | -235 | -1978 | 6430 | -3919 |
| Rps14 | -3675 | 1734 | 3410 | 7146 | -3493 |
| Rps15 | -5634 | 2477 | 239 | 7130 | -5513 |
| Rps15a | 369 | 608 | -3369 | 6779 | -5204 |
| Rps16 | -4792 | 2799 | -1537 | 6267 | -5455 |
| Rps17 | -5260 | -1557 | 1246 | 7182 | -6746 |
| Rps18 | -4838 | 1158 | 194 | 6830 | -4753 |
| Rps19 | -6105 | -2857 | -5576 | 6611 | -5782 |
| Rps2 | -2017 | 387 | -812 | 6266 | -3726 |
| Rps20 | -4819 | -1197 | -4402 | 5625 | -7090 |
| Rps21 | -4549 | -3950 | -722 | 7488 | -7191 |
| Rps23 | -6959 | 2961 | -3533 | 6890 | -7067 |
| Rps24 | -6377 | -301 | -5394 | 5997 | -5015 |
| Rps25 | -6573 | -1150 | -1883 | 6238 | -5538 |
| Rps26 | -5325 | 3572 | -3697 | 5769 | -6007 |
| Rps27 | -5449 | -2098 | 2068 | 7449 | -7364 |
| Rps27a | -6372 | -7132 | -2043 | 6853 | -6401 |
| Rps27l | -4990 | -3246 | -4325 | 6048 | -3758 |
| Rps28 | -2854 | -2799 | 2837 | 7397 | -7470 |
| Rps29 | -234 | -4717 | -446 | 7482 | -7465 |
| Rps3 | -5535 | 1738 | -2705 | 6117 | -1500 |
| Rps3a1 | -6001 | 295 | -2164 | 5731 | -4251 |
| Rps4x | -3555 | -300 | -4680 | 5409 | -4453 |
| Rps5 | -4284 | 1344 | -1916 | 5993 | -4583 |
| Rps6 | -4272 | 4707 | 1599 | 6014 | -5295 |
| Rps7 | -5696 | 1849 | -3387 | 6808 | -5804 |
| Rps8 | -6704 | -566 | -5243 | 7004 | -6741 |
| Rps9 | -5004 | 1757 | -844 | 6794 | -4576 |
| Rpsa | -5034 | -2245 | -4844 | 5145 | -2970 |
| Uba52 | -2504 | 5042 | 585 | 6605 | -5655 |
SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE
| metric | value |
|---|---|
| setSize | 106 |
| pMANOVA | 6.08e-69 |
| p.adjustMANOVA | 2.33e-66 |
| s.dist | 1.1 |
| s.hyp | -0.481 |
| s.hip | 0.0605 |
| s.amy | -0.206 |
| s.pag | 0.755 |
| s.ni | -0.611 |
| p.hyp | 1.13e-17 |
| p.hip | 0.282 |
| p.amy | 0.000243 |
| p.pag | 2.89e-41 |
| p.ni | 1.58e-27 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | ni |
|---|---|---|
| Rps29 | 7482 | -7465 |
| Rpl38 | 7427 | -7458 |
| Rps28 | 7397 | -7470 |
| Rpl39 | 7435 | -7398 |
| Rps27 | 7449 | -7364 |
| Rps21 | 7488 | -7191 |
| Rpl37a | 7353 | -7233 |
| Rpl37 | 7169 | -7308 |
| Rpl23 | 6983 | -7403 |
| Rpl35a | 7450 | -6779 |
| Rpl36al | 7142 | -7041 |
| Rpl35 | 7203 | -6944 |
| Sec61b | 7337 | -6763 |
| Rps23 | 6890 | -7067 |
| Rps17 | 7182 | -6746 |
| Rpl36a | 6846 | -6933 |
| Rps8 | 7004 | -6741 |
| Rpl30 | 6489 | -7269 |
| Rpl21 | 6613 | -7105 |
| Rpl31 | 7055 | -6596 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Ddost | -3345 | -3221 | 2102 | 2616 | -4771 |
| Fau | -5907 | 1583 | 1608 | 7212 | -5383 |
| Rpl10 | 7552 | 2305 | -6483 | 1980 | 1798 |
| Rpl10a | -4754 | 5887 | -3904 | 6315 | -6264 |
| Rpl11 | -7040 | -1610 | -1752 | 7106 | -5100 |
| Rpl12 | -1293 | 111 | -1276 | 5593 | -4815 |
| Rpl13 | -5435 | 705 | -309 | 7111 | -4751 |
| Rpl13a | -6127 | -800 | -4926 | 6137 | -3678 |
| Rpl14 | -4973 | 3377 | -3827 | 6231 | -6184 |
| Rpl15 | -1081 | 4664 | -97 | 5670 | -5225 |
| Rpl17 | -6154 | 1812 | -4356 | 5972 | -3587 |
| Rpl18 | -3623 | 1407 | 1250 | 6814 | -5632 |
| Rpl18a | -1090 | 3984 | -5189 | 6777 | -4423 |
| Rpl19 | -6145 | 1844 | 1393 | 7139 | -5256 |
| Rpl21 | -5242 | 1494 | -2632 | 6613 | -7105 |
| Rpl22 | 2309 | 1493 | 135 | 7361 | -5393 |
| Rpl22l1 | -6274 | -4977 | -2367 | 6270 | -5683 |
| Rpl23 | -4886 | -1314 | -5284 | 6983 | -7403 |
| Rpl23a | -5685 | 181 | -4668 | 5986 | -6814 |
| Rpl24 | -6576 | 1391 | -3886 | 6934 | -6380 |
| Rpl26 | -6659 | 1690 | -587 | 7025 | -6436 |
| Rpl27 | -6845 | 1737 | -3419 | 6972 | -3911 |
| Rpl27a | -5517 | 3660 | -2513 | 5849 | -4735 |
| Rpl28 | -1279 | 5641 | -1248 | 5705 | -5460 |
| Rpl29 | -1125 | 4140 | -4187 | 6593 | -5922 |
| Rpl3 | -4393 | 97 | 1158 | 6008 | -4443 |
| Rpl30 | -3489 | -1769 | -4305 | 6489 | -7269 |
| Rpl31 | -6836 | -3203 | -1412 | 7055 | -6596 |
| Rpl32 | -4734 | -2231 | 1048 | 7325 | -5634 |
| Rpl34 | -5472 | -4039 | -1304 | 7052 | -5665 |
| Rpl35 | -5746 | -5044 | -3769 | 7203 | -6944 |
| Rpl35a | -5482 | -3840 | 570 | 7450 | -6779 |
| Rpl36 | -4150 | -526 | -925 | 7394 | -6244 |
| Rpl36a | -5737 | 966 | -3217 | 6846 | -6933 |
| Rpl36al | -5513 | 1911 | -471 | 7142 | -7041 |
| Rpl37 | -4803 | -2009 | -157 | 7169 | -7308 |
| Rpl37a | -5196 | -2693 | 70 | 7353 | -7233 |
| Rpl38 | -4285 | -3890 | 857 | 7427 | -7458 |
| Rpl39 | -6226 | -2451 | 1477 | 7435 | -7398 |
| Rpl4 | -4925 | 1852 | -4074 | 6135 | -4712 |
| Rpl5 | 5744 | -2476 | -3141 | 5665 | 42 |
| Rpl6 | -5411 | 5527 | -1164 | 5021 | -4217 |
| Rpl7 | -5113 | 1762 | 151 | 6242 | -4040 |
| Rpl7a | -3564 | 4076 | 1931 | 6938 | -2667 |
| Rpl8 | -3703 | 3543 | -3664 | 6481 | -4491 |
| Rpl9 | -5504 | 344 | 903 | 6756 | -2526 |
| Rplp0 | -3763 | 4412 | -942 | 6357 | 956 |
| Rplp1 | -3659 | -3603 | -814 | 6990 | -6512 |
| Rplp2 | -1405 | 721 | 5081 | 7200 | -5799 |
| Rpn1 | -4337 | -7680 | -5653 | 954 | -6688 |
| Rpn2 | 567 | 2281 | -341 | -1514 | -2629 |
| Rps10 | -5436 | 1596 | -1596 | 7118 | -2524 |
| Rps11 | -6088 | -966 | -1330 | 6240 | -6425 |
| Rps12 | -6536 | 2445 | -4827 | 7047 | -5574 |
| Rps13 | -2674 | -235 | -1978 | 6430 | -3919 |
| Rps14 | -3675 | 1734 | 3410 | 7146 | -3493 |
| Rps15 | -5634 | 2477 | 239 | 7130 | -5513 |
| Rps15a | 369 | 608 | -3369 | 6779 | -5204 |
| Rps16 | -4792 | 2799 | -1537 | 6267 | -5455 |
| Rps17 | -5260 | -1557 | 1246 | 7182 | -6746 |
| Rps18 | -4838 | 1158 | 194 | 6830 | -4753 |
| Rps19 | -6105 | -2857 | -5576 | 6611 | -5782 |
| Rps2 | -2017 | 387 | -812 | 6266 | -3726 |
| Rps20 | -4819 | -1197 | -4402 | 5625 | -7090 |
| Rps21 | -4549 | -3950 | -722 | 7488 | -7191 |
| Rps23 | -6959 | 2961 | -3533 | 6890 | -7067 |
| Rps24 | -6377 | -301 | -5394 | 5997 | -5015 |
| Rps25 | -6573 | -1150 | -1883 | 6238 | -5538 |
| Rps26 | -5325 | 3572 | -3697 | 5769 | -6007 |
| Rps27 | -5449 | -2098 | 2068 | 7449 | -7364 |
| Rps27a | -6372 | -7132 | -2043 | 6853 | -6401 |
| Rps27l | -4990 | -3246 | -4325 | 6048 | -3758 |
| Rps28 | -2854 | -2799 | 2837 | 7397 | -7470 |
| Rps29 | -234 | -4717 | -446 | 7482 | -7465 |
| Rps3 | -5535 | 1738 | -2705 | 6117 | -1500 |
| Rps3a1 | -6001 | 295 | -2164 | 5731 | -4251 |
| Rps4x | -3555 | -300 | -4680 | 5409 | -4453 |
| Rps5 | -4284 | 1344 | -1916 | 5993 | -4583 |
| Rps6 | -4272 | 4707 | 1599 | 6014 | -5295 |
| Rps7 | -5696 | 1849 | -3387 | 6808 | -5804 |
| Rps8 | -6704 | -566 | -5243 | 7004 | -6741 |
| Rps9 | -5004 | 1757 | -844 | 6794 | -4576 |
| Rpsa | -5034 | -2245 | -4844 | 5145 | -2970 |
| Sec11a | -7127 | -6550 | -5434 | 6199 | -3396 |
| Sec11c | -6474 | -2330 | -1390 | 7039 | -5441 |
| Sec61a1 | -1747 | -8379 | -6972 | 893 | -2327 |
| Sec61a2 | 2624 | -7285 | 696 | 1163 | -1570 |
| Sec61b | -3658 | 2229 | 2906 | 7337 | -6763 |
| Sec61g | -2940 | -4761 | -6122 | 6367 | 3468 |
| Spcs1 | -4369 | 1863 | -1685 | 6189 | -4700 |
| Spcs2 | -5799 | -5164 | -4098 | 4006 | -4171 |
| Spcs3 | -5662 | -7747 | 582 | 5 | 7366 |
| Srp14 | -6588 | 1875 | 1614 | 6416 | -5439 |
| Srp19 | -5268 | 6274 | -2237 | 5258 | -5856 |
| Srp54a | 1906 | -2837 | -5232 | 1541 | -2688 |
| Srp68 | 1016 | -7311 | 1841 | -1098 | 6797 |
| Srp72 | 3704 | 4824 | 509 | -5882 | 1592 |
| Srp9 | -4785 | 4091 | 702 | 6767 | -1805 |
| Srpr | 2424 | -3797 | -3773 | -5219 | 6962 |
| Srprb | -4307 | -4558 | -1862 | 4654 | -2825 |
| Ssr1 | 1409 | -340 | -3512 | -2483 | 1323 |
| Ssr2 | -3113 | 4494 | 3015 | 5354 | -290 |
| Ssr3 | -5658 | 1122 | -2992 | 2453 | 3971 |
| Ssr4 | -4733 | 232 | 2302 | 5827 | -2902 |
| Tram1 | -5082 | -1901 | -2689 | -6019 | -2866 |
| Uba52 | -2504 | 5042 | 585 | 6605 | -5655 |
ATTENUATION PHASE
| metric | value |
|---|---|
| setSize | 23 |
| pMANOVA | 8.18e-10 |
| p.adjustMANOVA | 1.33e-08 |
| s.dist | 1.09 |
| s.hyp | -0.555 |
| s.hip | -0.474 |
| s.amy | -0.39 |
| s.pag | -0.382 |
| s.ni | -0.594 |
| p.hyp | 4.09e-06 |
| p.hip | 8.3e-05 |
| p.amy | 0.0012 |
| p.pag | 0.00153 |
| p.ni | 8.16e-07 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | ni | hyp |
|---|---|---|
| Serpinh1 | -7457 | -8169 |
| Hspb1 | -7148 | -8007 |
| Hspa1b | -6798 | -8134 |
| Hsph1 | -6613 | -8099 |
| Fkbp4 | -6510 | -8071 |
| Hspa1a | -6471 | -8073 |
| Hsp90ab1 | -6462 | -7658 |
| Hsp90aa1 | -6162 | -7973 |
| Hspa8 | -6347 | -7640 |
| Dnajb1 | -5879 | -8118 |
| Ptges3 | -6040 | -7744 |
| Hsf1 | -6216 | -5123 |
| Hsbp1 | -4395 | -5762 |
| Ubb | -5290 | -4378 |
| Dnajb6 | -3746 | -5164 |
| Mrpl18 | -3037 | -5890 |
| Hspa1l | -6233 | -2214 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Col4a6 | 7726 | 1733 | -5086 | -2425 | 2423 |
| Crebbp | 5856 | -6540 | 2739 | -5698 | -6903 |
| Dedd2 | -6503 | -6839 | -6868 | -4963 | 2937 |
| Dnajb1 | -8118 | -8530 | -7783 | -7821 | -5879 |
| Dnajb6 | -5164 | 1333 | -1168 | 4244 | -3746 |
| Ep300 | 1346 | -3349 | -2137 | -4410 | 4066 |
| Fkbp4 | -8071 | -8446 | -7982 | -4084 | -6510 |
| Hsbp1 | -5762 | 4518 | 3646 | 6500 | -4395 |
| Hsf1 | -5123 | -2646 | 2144 | 75 | -6216 |
| Hsp90aa1 | -7973 | -8277 | -7326 | -4822 | -6162 |
| Hsp90ab1 | -7658 | -7115 | -4184 | -3700 | -6462 |
| Hspa1a | -8073 | -7910 | -7847 | -7813 | -6471 |
| Hspa1b | -8134 | -8449 | -7884 | -8270 | -6798 |
| Hspa1l | -2214 | 5884 | 2957 | -7401 | -6233 |
| Hspa2 | 2167 | -541 | 7295 | -5357 | -3387 |
| Hspa8 | -7640 | -8365 | -7244 | -4298 | -6347 |
| Hspb1 | -8007 | -8589 | -7986 | -8289 | -7148 |
| Hsph1 | -8099 | -8525 | -7948 | -8014 | -6613 |
| Mrpl18 | -5890 | -1549 | -1994 | 5860 | -3037 |
| Ptges3 | -7744 | -7847 | -6150 | -2080 | -6040 |
| Serpinh1 | -8169 | -8568 | -7988 | -8376 | -7457 |
| Tnfrsf21 | -435 | -6492 | 5944 | -5259 | 3980 |
| Ubb | -4378 | 3667 | 1287 | 6541 | -5290 |
ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES
| metric | value |
|---|---|
| setSize | 10 |
| pMANOVA | 0.000453 |
| p.adjustMANOVA | 0.00225 |
| s.dist | 1.08 |
| s.hyp | -0.516 |
| s.hip | -0.662 |
| s.amy | -0.503 |
| s.pag | -0.171 |
| s.ni | -0.414 |
| p.hyp | 0.0047 |
| p.hip | 0.000289 |
| p.amy | 0.00589 |
| p.pag | 0.35 |
| p.ni | 0.0234 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | hip | hyp |
|---|---|---|
| Hspa5 | -8614 | -8142 |
| Ddit3 | -8557 | -8087 |
| Xbp1 | -8605 | -7999 |
| Hsp90b1 | -8424 | -7732 |
| Calr | -8556 | -7354 |
| Atf4 | -7556 | -5109 |
| Nfyb | -3590 | -6572 |
| Nfya | -6390 | -1638 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Atf4 | -5109 | -7556 | -3593 | 7029 | -2762 |
| Atf6 | 7586 | -2375 | 5449 | -3372 | 8083 |
| Calr | -7354 | -8556 | -7756 | -5638 | -7238 |
| Ddit3 | -8087 | -8557 | -6904 | 5070 | -7401 |
| Hsp90b1 | -7732 | -8424 | -7893 | -4419 | -7388 |
| Hspa5 | -8142 | -8614 | -7975 | -8202 | -7402 |
| Nfya | -1638 | -6390 | -7828 | -4497 | 891 |
| Nfyb | -6572 | -3590 | 4348 | 455 | -2550 |
| Nfyc | 1976 | 3520 | -45 | 3546 | 4908 |
| Xbp1 | -7999 | -8605 | -7945 | -7851 | -7288 |
EUKARYOTIC TRANSLATION INITIATION
| metric | value |
|---|---|
| setSize | 114 |
| pMANOVA | 4.37e-62 |
| p.adjustMANOVA | 8.39e-60 |
| s.dist | 1.01 |
| s.hyp | -0.426 |
| s.hip | 0.106 |
| s.amy | -0.135 |
| s.pag | 0.744 |
| s.ni | -0.501 |
| p.hyp | 3.8e-15 |
| p.hip | 0.0503 |
| p.amy | 0.0128 |
| p.pag | 5.38e-43 |
| p.ni | 2.36e-20 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | ni |
|---|---|---|
| Rps29 | 7482 | -7465 |
| Rpl38 | 7427 | -7458 |
| Rps28 | 7397 | -7470 |
| Rpl39 | 7435 | -7398 |
| Rps27 | 7449 | -7364 |
| Rps21 | 7488 | -7191 |
| Rpl37a | 7353 | -7233 |
| Rpl37 | 7169 | -7308 |
| Rpl23 | 6983 | -7403 |
| Rpl35a | 7450 | -6779 |
| Rpl36al | 7142 | -7041 |
| Rpl35 | 7203 | -6944 |
| Rps23 | 6890 | -7067 |
| Rps17 | 7182 | -6746 |
| Rpl36a | 6846 | -6933 |
| Rps8 | 7004 | -6741 |
| Rpl30 | 6489 | -7269 |
| Rpl21 | 6613 | -7105 |
| Rpl31 | 7055 | -6596 |
| Rpl36 | 7394 | -6244 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Eif1ax | -5050 | 563 | -1955 | -625 | 7369 |
| Eif2b1 | 2982 | 1450 | -901 | 6024 | 5116 |
| Eif2b2 | -5516 | -4454 | 2377 | 5658 | 8178 |
| Eif2b3 | 2215 | 2475 | 828 | -950 | -3759 |
| Eif2b4 | 7283 | 38 | 2725 | 4551 | 2240 |
| Eif2b5 | 1288 | -5596 | 2078 | 3337 | 6169 |
| Eif2s1 | -6701 | -39 | -1217 | 5813 | 2921 |
| Eif2s2 | -4538 | -2403 | -5282 | 4050 | -5700 |
| Eif2s3x | 17 | -3878 | -3881 | -646 | 1396 |
| Eif3a | -6953 | -3944 | 1407 | -5013 | -7267 |
| Eif3b | 1168 | -6669 | 317 | 185 | 1132 |
| Eif3c | 5026 | 1285 | 6212 | 1990 | -609 |
| Eif3d | -246 | 5830 | 31 | 5012 | 3393 |
| Eif3e | -3996 | -271 | -1571 | 3711 | -2173 |
| Eif3f | -1429 | -114 | 5534 | 4747 | 1677 |
| Eif3g | -6158 | 4506 | -1026 | 6812 | -3309 |
| Eif3h | -5774 | 4130 | -1152 | 6092 | 398 |
| Eif3i | -5204 | 989 | 3667 | 6588 | 1783 |
| Eif3j1 | -933 | -3758 | -6113 | 5970 | -3553 |
| Eif3j2 | -7756 | -7169 | -7559 | -7227 | -640 |
| Eif3k | -5937 | 2750 | -2777 | 5339 | -2714 |
| Eif3l | 1203 | 1231 | 2859 | 4204 | 1293 |
| Eif3m | -3122 | 5534 | -872 | 6520 | 2334 |
| Eif4a1 | -5925 | -6104 | 4369 | 5645 | -6174 |
| Eif4a2 | -6255 | 2282 | -1778 | 4032 | 6477 |
| Eif4b | 7049 | 1455 | 4759 | -676 | 3264 |
| Eif4e | -2868 | 336 | -2621 | 4261 | 2119 |
| Eif4ebp1 | -884 | 6714 | 2834 | 3590 | -216 |
| Eif4g1 | 3439 | 953 | 4989 | -4135 | 2939 |
| Eif4h | 3731 | 704 | 3643 | 3900 | 5149 |
| Eif5 | 1858 | 2090 | 1643 | 4507 | 7317 |
| Eif5b | -1320 | -3993 | -2163 | 2055 | -7070 |
| Fau | -5907 | 1583 | 1608 | 7212 | -5383 |
| Pabpc1 | -4196 | -1362 | 4329 | -2356 | -620 |
| Rpl10 | 7552 | 2305 | -6483 | 1980 | 1798 |
| Rpl10a | -4754 | 5887 | -3904 | 6315 | -6264 |
| Rpl11 | -7040 | -1610 | -1752 | 7106 | -5100 |
| Rpl12 | -1293 | 111 | -1276 | 5593 | -4815 |
| Rpl13 | -5435 | 705 | -309 | 7111 | -4751 |
| Rpl13a | -6127 | -800 | -4926 | 6137 | -3678 |
| Rpl14 | -4973 | 3377 | -3827 | 6231 | -6184 |
| Rpl15 | -1081 | 4664 | -97 | 5670 | -5225 |
| Rpl17 | -6154 | 1812 | -4356 | 5972 | -3587 |
| Rpl18 | -3623 | 1407 | 1250 | 6814 | -5632 |
| Rpl18a | -1090 | 3984 | -5189 | 6777 | -4423 |
| Rpl19 | -6145 | 1844 | 1393 | 7139 | -5256 |
| Rpl21 | -5242 | 1494 | -2632 | 6613 | -7105 |
| Rpl22 | 2309 | 1493 | 135 | 7361 | -5393 |
| Rpl22l1 | -6274 | -4977 | -2367 | 6270 | -5683 |
| Rpl23 | -4886 | -1314 | -5284 | 6983 | -7403 |
| Rpl23a | -5685 | 181 | -4668 | 5986 | -6814 |
| Rpl24 | -6576 | 1391 | -3886 | 6934 | -6380 |
| Rpl26 | -6659 | 1690 | -587 | 7025 | -6436 |
| Rpl27 | -6845 | 1737 | -3419 | 6972 | -3911 |
| Rpl27a | -5517 | 3660 | -2513 | 5849 | -4735 |
| Rpl28 | -1279 | 5641 | -1248 | 5705 | -5460 |
| Rpl29 | -1125 | 4140 | -4187 | 6593 | -5922 |
| Rpl3 | -4393 | 97 | 1158 | 6008 | -4443 |
| Rpl30 | -3489 | -1769 | -4305 | 6489 | -7269 |
| Rpl31 | -6836 | -3203 | -1412 | 7055 | -6596 |
| Rpl32 | -4734 | -2231 | 1048 | 7325 | -5634 |
| Rpl34 | -5472 | -4039 | -1304 | 7052 | -5665 |
| Rpl35 | -5746 | -5044 | -3769 | 7203 | -6944 |
| Rpl35a | -5482 | -3840 | 570 | 7450 | -6779 |
| Rpl36 | -4150 | -526 | -925 | 7394 | -6244 |
| Rpl36a | -5737 | 966 | -3217 | 6846 | -6933 |
| Rpl36al | -5513 | 1911 | -471 | 7142 | -7041 |
| Rpl37 | -4803 | -2009 | -157 | 7169 | -7308 |
| Rpl37a | -5196 | -2693 | 70 | 7353 | -7233 |
| Rpl38 | -4285 | -3890 | 857 | 7427 | -7458 |
| Rpl39 | -6226 | -2451 | 1477 | 7435 | -7398 |
| Rpl4 | -4925 | 1852 | -4074 | 6135 | -4712 |
| Rpl5 | 5744 | -2476 | -3141 | 5665 | 42 |
| Rpl6 | -5411 | 5527 | -1164 | 5021 | -4217 |
| Rpl7 | -5113 | 1762 | 151 | 6242 | -4040 |
| Rpl7a | -3564 | 4076 | 1931 | 6938 | -2667 |
| Rpl8 | -3703 | 3543 | -3664 | 6481 | -4491 |
| Rpl9 | -5504 | 344 | 903 | 6756 | -2526 |
| Rplp0 | -3763 | 4412 | -942 | 6357 | 956 |
| Rplp1 | -3659 | -3603 | -814 | 6990 | -6512 |
| Rplp2 | -1405 | 721 | 5081 | 7200 | -5799 |
| Rps10 | -5436 | 1596 | -1596 | 7118 | -2524 |
| Rps11 | -6088 | -966 | -1330 | 6240 | -6425 |
| Rps12 | -6536 | 2445 | -4827 | 7047 | -5574 |
| Rps13 | -2674 | -235 | -1978 | 6430 | -3919 |
| Rps14 | -3675 | 1734 | 3410 | 7146 | -3493 |
| Rps15 | -5634 | 2477 | 239 | 7130 | -5513 |
| Rps15a | 369 | 608 | -3369 | 6779 | -5204 |
| Rps16 | -4792 | 2799 | -1537 | 6267 | -5455 |
| Rps17 | -5260 | -1557 | 1246 | 7182 | -6746 |
| Rps18 | -4838 | 1158 | 194 | 6830 | -4753 |
| Rps19 | -6105 | -2857 | -5576 | 6611 | -5782 |
| Rps2 | -2017 | 387 | -812 | 6266 | -3726 |
| Rps20 | -4819 | -1197 | -4402 | 5625 | -7090 |
| Rps21 | -4549 | -3950 | -722 | 7488 | -7191 |
| Rps23 | -6959 | 2961 | -3533 | 6890 | -7067 |
| Rps24 | -6377 | -301 | -5394 | 5997 | -5015 |
| Rps25 | -6573 | -1150 | -1883 | 6238 | -5538 |
| Rps26 | -5325 | 3572 | -3697 | 5769 | -6007 |
| Rps27 | -5449 | -2098 | 2068 | 7449 | -7364 |
| Rps27a | -6372 | -7132 | -2043 | 6853 | -6401 |
| Rps27l | -4990 | -3246 | -4325 | 6048 | -3758 |
| Rps28 | -2854 | -2799 | 2837 | 7397 | -7470 |
| Rps29 | -234 | -4717 | -446 | 7482 | -7465 |
| Rps3 | -5535 | 1738 | -2705 | 6117 | -1500 |
| Rps3a1 | -6001 | 295 | -2164 | 5731 | -4251 |
| Rps4x | -3555 | -300 | -4680 | 5409 | -4453 |
| Rps5 | -4284 | 1344 | -1916 | 5993 | -4583 |
| Rps6 | -4272 | 4707 | 1599 | 6014 | -5295 |
| Rps7 | -5696 | 1849 | -3387 | 6808 | -5804 |
| Rps8 | -6704 | -566 | -5243 | 7004 | -6741 |
| Rps9 | -5004 | 1757 | -844 | 6794 | -4576 |
| Rpsa | -5034 | -2245 | -4844 | 5145 | -2970 |
| Uba52 | -2504 | 5042 | 585 | 6605 | -5655 |
SELENOAMINO ACID METABOLISM
| metric | value |
|---|---|
| setSize | 107 |
| pMANOVA | 6.38e-57 |
| p.adjustMANOVA | 8.17e-55 |
| s.dist | 1.01 |
| s.hyp | -0.423 |
| s.hip | 0.128 |
| s.amy | -0.158 |
| s.pag | 0.717 |
| s.ni | -0.525 |
| p.hyp | 4.1e-14 |
| p.hip | 0.0227 |
| p.amy | 0.00468 |
| p.pag | 1.01e-37 |
| p.ni | 5.83e-21 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | ni |
|---|---|---|
| Rps29 | 7482 | -7465 |
| Rpl38 | 7427 | -7458 |
| Rps28 | 7397 | -7470 |
| Rpl39 | 7435 | -7398 |
| Rps27 | 7449 | -7364 |
| Rps21 | 7488 | -7191 |
| Rpl37a | 7353 | -7233 |
| Rpl37 | 7169 | -7308 |
| Rpl23 | 6983 | -7403 |
| Rpl35a | 7450 | -6779 |
| Rpl36al | 7142 | -7041 |
| Rpl35 | 7203 | -6944 |
| Rps23 | 6890 | -7067 |
| Rps17 | 7182 | -6746 |
| Rpl36a | 6846 | -6933 |
| Rps8 | 7004 | -6741 |
| Rpl30 | 6489 | -7269 |
| Rpl21 | 6613 | -7105 |
| Rpl31 | 7055 | -6596 |
| Rpl36 | 7394 | -6244 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Ahcy | -1194 | 3109 | 1954 | 3885 | -3002 |
| Aimp1 | -2821 | 5719 | 3587 | 6197 | -3383 |
| Aimp2 | -6494 | 1723 | 1316 | 5025 | -1429 |
| Cbs | 7220 | 3331 | -1267 | 3524 | 5933 |
| Cth | -1300 | 5137 | -4665 | -4102 | 6059 |
| Dars | -7892 | 5922 | -3590 | 920 | 4739 |
| Eef1e1 | -4089 | 2160 | -2652 | 3568 | -2112 |
| Eefsec | 4076 | -2075 | 7260 | -1847 | -2318 |
| Eprs | 7535 | -3999 | 5735 | 731 | -722 |
| Fau | -5907 | 1583 | 1608 | 7212 | -5383 |
| Gsr | -7789 | 149 | -1532 | -1326 | -4520 |
| Hnmt | -7450 | -1938 | -4403 | 5600 | -1750 |
| Iars | 3479 | -5780 | -3489 | -6464 | 6023 |
| Kars | -3919 | -5643 | -4095 | 4476 | 3554 |
| Lars | 7141 | 5295 | 6692 | 2736 | 1842 |
| Mars1 | 1094 | -4538 | 4234 | 181 | -4294 |
| Papss1 | 156 | 1462 | 207 | -2761 | 1131 |
| Papss2 | -4890 | 4821 | -7690 | -4656 | 892 |
| Pstk | -983 | 419 | 4484 | 7232 | 2128 |
| Qars | -1177 | -2125 | 1998 | -1044 | 5216 |
| Rars | -1491 | -2819 | -3228 | 5096 | 3454 |
| Rpl10 | 7552 | 2305 | -6483 | 1980 | 1798 |
| Rpl10a | -4754 | 5887 | -3904 | 6315 | -6264 |
| Rpl11 | -7040 | -1610 | -1752 | 7106 | -5100 |
| Rpl12 | -1293 | 111 | -1276 | 5593 | -4815 |
| Rpl13 | -5435 | 705 | -309 | 7111 | -4751 |
| Rpl13a | -6127 | -800 | -4926 | 6137 | -3678 |
| Rpl14 | -4973 | 3377 | -3827 | 6231 | -6184 |
| Rpl15 | -1081 | 4664 | -97 | 5670 | -5225 |
| Rpl17 | -6154 | 1812 | -4356 | 5972 | -3587 |
| Rpl18 | -3623 | 1407 | 1250 | 6814 | -5632 |
| Rpl18a | -1090 | 3984 | -5189 | 6777 | -4423 |
| Rpl19 | -6145 | 1844 | 1393 | 7139 | -5256 |
| Rpl21 | -5242 | 1494 | -2632 | 6613 | -7105 |
| Rpl22 | 2309 | 1493 | 135 | 7361 | -5393 |
| Rpl22l1 | -6274 | -4977 | -2367 | 6270 | -5683 |
| Rpl23 | -4886 | -1314 | -5284 | 6983 | -7403 |
| Rpl23a | -5685 | 181 | -4668 | 5986 | -6814 |
| Rpl24 | -6576 | 1391 | -3886 | 6934 | -6380 |
| Rpl26 | -6659 | 1690 | -587 | 7025 | -6436 |
| Rpl27 | -6845 | 1737 | -3419 | 6972 | -3911 |
| Rpl27a | -5517 | 3660 | -2513 | 5849 | -4735 |
| Rpl28 | -1279 | 5641 | -1248 | 5705 | -5460 |
| Rpl29 | -1125 | 4140 | -4187 | 6593 | -5922 |
| Rpl3 | -4393 | 97 | 1158 | 6008 | -4443 |
| Rpl30 | -3489 | -1769 | -4305 | 6489 | -7269 |
| Rpl31 | -6836 | -3203 | -1412 | 7055 | -6596 |
| Rpl32 | -4734 | -2231 | 1048 | 7325 | -5634 |
| Rpl34 | -5472 | -4039 | -1304 | 7052 | -5665 |
| Rpl35 | -5746 | -5044 | -3769 | 7203 | -6944 |
| Rpl35a | -5482 | -3840 | 570 | 7450 | -6779 |
| Rpl36 | -4150 | -526 | -925 | 7394 | -6244 |
| Rpl36a | -5737 | 966 | -3217 | 6846 | -6933 |
| Rpl36al | -5513 | 1911 | -471 | 7142 | -7041 |
| Rpl37 | -4803 | -2009 | -157 | 7169 | -7308 |
| Rpl37a | -5196 | -2693 | 70 | 7353 | -7233 |
| Rpl38 | -4285 | -3890 | 857 | 7427 | -7458 |
| Rpl39 | -6226 | -2451 | 1477 | 7435 | -7398 |
| Rpl4 | -4925 | 1852 | -4074 | 6135 | -4712 |
| Rpl5 | 5744 | -2476 | -3141 | 5665 | 42 |
| Rpl6 | -5411 | 5527 | -1164 | 5021 | -4217 |
| Rpl7 | -5113 | 1762 | 151 | 6242 | -4040 |
| Rpl7a | -3564 | 4076 | 1931 | 6938 | -2667 |
| Rpl8 | -3703 | 3543 | -3664 | 6481 | -4491 |
| Rpl9 | -5504 | 344 | 903 | 6756 | -2526 |
| Rplp0 | -3763 | 4412 | -942 | 6357 | 956 |
| Rplp1 | -3659 | -3603 | -814 | 6990 | -6512 |
| Rplp2 | -1405 | 721 | 5081 | 7200 | -5799 |
| Rps10 | -5436 | 1596 | -1596 | 7118 | -2524 |
| Rps11 | -6088 | -966 | -1330 | 6240 | -6425 |
| Rps12 | -6536 | 2445 | -4827 | 7047 | -5574 |
| Rps13 | -2674 | -235 | -1978 | 6430 | -3919 |
| Rps14 | -3675 | 1734 | 3410 | 7146 | -3493 |
| Rps15 | -5634 | 2477 | 239 | 7130 | -5513 |
| Rps15a | 369 | 608 | -3369 | 6779 | -5204 |
| Rps16 | -4792 | 2799 | -1537 | 6267 | -5455 |
| Rps17 | -5260 | -1557 | 1246 | 7182 | -6746 |
| Rps18 | -4838 | 1158 | 194 | 6830 | -4753 |
| Rps19 | -6105 | -2857 | -5576 | 6611 | -5782 |
| Rps2 | -2017 | 387 | -812 | 6266 | -3726 |
| Rps20 | -4819 | -1197 | -4402 | 5625 | -7090 |
| Rps21 | -4549 | -3950 | -722 | 7488 | -7191 |
| Rps23 | -6959 | 2961 | -3533 | 6890 | -7067 |
| Rps24 | -6377 | -301 | -5394 | 5997 | -5015 |
| Rps25 | -6573 | -1150 | -1883 | 6238 | -5538 |
| Rps26 | -5325 | 3572 | -3697 | 5769 | -6007 |
| Rps27 | -5449 | -2098 | 2068 | 7449 | -7364 |
| Rps27a | -6372 | -7132 | -2043 | 6853 | -6401 |
| Rps27l | -4990 | -3246 | -4325 | 6048 | -3758 |
| Rps28 | -2854 | -2799 | 2837 | 7397 | -7470 |
| Rps29 | -234 | -4717 | -446 | 7482 | -7465 |
| Rps3 | -5535 | 1738 | -2705 | 6117 | -1500 |
| Rps3a1 | -6001 | 295 | -2164 | 5731 | -4251 |
| Rps4x | -3555 | -300 | -4680 | 5409 | -4453 |
| Rps5 | -4284 | 1344 | -1916 | 5993 | -4583 |
| Rps6 | -4272 | 4707 | 1599 | 6014 | -5295 |
| Rps7 | -5696 | 1849 | -3387 | 6808 | -5804 |
| Rps8 | -6704 | -566 | -5243 | 7004 | -6741 |
| Rps9 | -5004 | 1757 | -844 | 6794 | -4576 |
| Rpsa | -5034 | -2245 | -4844 | 5145 | -2970 |
| Sars | -523 | 3642 | 2351 | 4931 | 712 |
| Scly | 3231 | 4894 | -1268 | 1064 | 6874 |
| Secisbp2 | -2948 | -2734 | 3184 | -1713 | 387 |
| Sephs2 | -5146 | 2835 | 7038 | 3598 | 6996 |
| Sepsecs | 6714 | -2336 | -3554 | 1576 | -1467 |
| Txnrd1 | -6413 | -4368 | -7174 | -4169 | 1474 |
| Uba52 | -2504 | 5042 | 585 | 6605 | -5655 |
NONSENSE MEDIATED DECAY NMD
| metric | value |
|---|---|
| setSize | 109 |
| pMANOVA | 1.23e-54 |
| p.adjustMANOVA | 1.29e-52 |
| s.dist | 0.972 |
| s.hyp | -0.385 |
| s.hip | 0.0938 |
| s.amy | -0.12 |
| s.pag | 0.669 |
| s.ni | -0.572 |
| p.hyp | 3.96e-12 |
| p.hip | 0.0908 |
| p.amy | 0.0307 |
| p.pag | 1.36e-33 |
| p.ni | 5.59e-25 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | ni |
|---|---|---|
| Rps29 | 7482 | -7465 |
| Rpl38 | 7427 | -7458 |
| Rps28 | 7397 | -7470 |
| Rpl39 | 7435 | -7398 |
| Rps27 | 7449 | -7364 |
| Rps21 | 7488 | -7191 |
| Rpl37a | 7353 | -7233 |
| Rpl37 | 7169 | -7308 |
| Rpl23 | 6983 | -7403 |
| Rpl35a | 7450 | -6779 |
| Rpl36al | 7142 | -7041 |
| Rpl35 | 7203 | -6944 |
| Rps23 | 6890 | -7067 |
| Rps17 | 7182 | -6746 |
| Rpl36a | 6846 | -6933 |
| Rps8 | 7004 | -6741 |
| Rpl30 | 6489 | -7269 |
| Rpl21 | 6613 | -7105 |
| Rpl31 | 7055 | -6596 |
| Rpl36 | 7394 | -6244 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Casc3 | 4984 | -4302 | 1439 | -5352 | 371 |
| Dcp1a | 6453 | -2002 | 1514 | -4220 | 6808 |
| Eif4a3 | 1584 | 3787 | 6555 | 6201 | -4877 |
| Eif4g1 | 3439 | 953 | 4989 | -4135 | 2939 |
| Etf1 | -4514 | -1719 | -5831 | 2237 | 745 |
| Fau | -5907 | 1583 | 1608 | 7212 | -5383 |
| Gspt1 | 1609 | -582 | -4047 | -5342 | 6563 |
| Gspt2 | -5177 | 6055 | 689 | -4954 | -1529 |
| Magoh | -6703 | -2382 | 1798 | 7239 | -4713 |
| Magohb | -8083 | -7545 | 1819 | 6954 | -6268 |
| Ncbp1 | 472 | -1721 | 5922 | 1206 | 2493 |
| Ncbp2 | -2016 | 5799 | 659 | 5157 | -5666 |
| Pabpc1 | -4196 | -1362 | 4329 | -2356 | -620 |
| Pnrc2 | -7026 | -2716 | -7067 | 2666 | 2349 |
| Ppp2ca | -1717 | 760 | -1274 | 4992 | 1219 |
| Ppp2r1a | 2450 | -1919 | 5720 | 293 | 3525 |
| Ppp2r2a | -3671 | -864 | -3361 | -1611 | -2344 |
| Rbm8a | -7955 | -5212 | -6869 | 2235 | -7128 |
| Rnps1 | -2423 | 1730 | 4062 | 1254 | -2459 |
| Rpl10 | 7552 | 2305 | -6483 | 1980 | 1798 |
| Rpl10a | -4754 | 5887 | -3904 | 6315 | -6264 |
| Rpl11 | -7040 | -1610 | -1752 | 7106 | -5100 |
| Rpl12 | -1293 | 111 | -1276 | 5593 | -4815 |
| Rpl13 | -5435 | 705 | -309 | 7111 | -4751 |
| Rpl13a | -6127 | -800 | -4926 | 6137 | -3678 |
| Rpl14 | -4973 | 3377 | -3827 | 6231 | -6184 |
| Rpl15 | -1081 | 4664 | -97 | 5670 | -5225 |
| Rpl17 | -6154 | 1812 | -4356 | 5972 | -3587 |
| Rpl18 | -3623 | 1407 | 1250 | 6814 | -5632 |
| Rpl18a | -1090 | 3984 | -5189 | 6777 | -4423 |
| Rpl19 | -6145 | 1844 | 1393 | 7139 | -5256 |
| Rpl21 | -5242 | 1494 | -2632 | 6613 | -7105 |
| Rpl22 | 2309 | 1493 | 135 | 7361 | -5393 |
| Rpl22l1 | -6274 | -4977 | -2367 | 6270 | -5683 |
| Rpl23 | -4886 | -1314 | -5284 | 6983 | -7403 |
| Rpl23a | -5685 | 181 | -4668 | 5986 | -6814 |
| Rpl24 | -6576 | 1391 | -3886 | 6934 | -6380 |
| Rpl26 | -6659 | 1690 | -587 | 7025 | -6436 |
| Rpl27 | -6845 | 1737 | -3419 | 6972 | -3911 |
| Rpl27a | -5517 | 3660 | -2513 | 5849 | -4735 |
| Rpl28 | -1279 | 5641 | -1248 | 5705 | -5460 |
| Rpl29 | -1125 | 4140 | -4187 | 6593 | -5922 |
| Rpl3 | -4393 | 97 | 1158 | 6008 | -4443 |
| Rpl30 | -3489 | -1769 | -4305 | 6489 | -7269 |
| Rpl31 | -6836 | -3203 | -1412 | 7055 | -6596 |
| Rpl32 | -4734 | -2231 | 1048 | 7325 | -5634 |
| Rpl34 | -5472 | -4039 | -1304 | 7052 | -5665 |
| Rpl35 | -5746 | -5044 | -3769 | 7203 | -6944 |
| Rpl35a | -5482 | -3840 | 570 | 7450 | -6779 |
| Rpl36 | -4150 | -526 | -925 | 7394 | -6244 |
| Rpl36a | -5737 | 966 | -3217 | 6846 | -6933 |
| Rpl36al | -5513 | 1911 | -471 | 7142 | -7041 |
| Rpl37 | -4803 | -2009 | -157 | 7169 | -7308 |
| Rpl37a | -5196 | -2693 | 70 | 7353 | -7233 |
| Rpl38 | -4285 | -3890 | 857 | 7427 | -7458 |
| Rpl39 | -6226 | -2451 | 1477 | 7435 | -7398 |
| Rpl4 | -4925 | 1852 | -4074 | 6135 | -4712 |
| Rpl5 | 5744 | -2476 | -3141 | 5665 | 42 |
| Rpl6 | -5411 | 5527 | -1164 | 5021 | -4217 |
| Rpl7 | -5113 | 1762 | 151 | 6242 | -4040 |
| Rpl7a | -3564 | 4076 | 1931 | 6938 | -2667 |
| Rpl8 | -3703 | 3543 | -3664 | 6481 | -4491 |
| Rpl9 | -5504 | 344 | 903 | 6756 | -2526 |
| Rplp0 | -3763 | 4412 | -942 | 6357 | 956 |
| Rplp1 | -3659 | -3603 | -814 | 6990 | -6512 |
| Rplp2 | -1405 | 721 | 5081 | 7200 | -5799 |
| Rps10 | -5436 | 1596 | -1596 | 7118 | -2524 |
| Rps11 | -6088 | -966 | -1330 | 6240 | -6425 |
| Rps12 | -6536 | 2445 | -4827 | 7047 | -5574 |
| Rps13 | -2674 | -235 | -1978 | 6430 | -3919 |
| Rps14 | -3675 | 1734 | 3410 | 7146 | -3493 |
| Rps15 | -5634 | 2477 | 239 | 7130 | -5513 |
| Rps15a | 369 | 608 | -3369 | 6779 | -5204 |
| Rps16 | -4792 | 2799 | -1537 | 6267 | -5455 |
| Rps17 | -5260 | -1557 | 1246 | 7182 | -6746 |
| Rps18 | -4838 | 1158 | 194 | 6830 | -4753 |
| Rps19 | -6105 | -2857 | -5576 | 6611 | -5782 |
| Rps2 | -2017 | 387 | -812 | 6266 | -3726 |
| Rps20 | -4819 | -1197 | -4402 | 5625 | -7090 |
| Rps21 | -4549 | -3950 | -722 | 7488 | -7191 |
| Rps23 | -6959 | 2961 | -3533 | 6890 | -7067 |
| Rps24 | -6377 | -301 | -5394 | 5997 | -5015 |
| Rps25 | -6573 | -1150 | -1883 | 6238 | -5538 |
| Rps26 | -5325 | 3572 | -3697 | 5769 | -6007 |
| Rps27 | -5449 | -2098 | 2068 | 7449 | -7364 |
| Rps27a | -6372 | -7132 | -2043 | 6853 | -6401 |
| Rps27l | -4990 | -3246 | -4325 | 6048 | -3758 |
| Rps28 | -2854 | -2799 | 2837 | 7397 | -7470 |
| Rps29 | -234 | -4717 | -446 | 7482 | -7465 |
| Rps3 | -5535 | 1738 | -2705 | 6117 | -1500 |
| Rps3a1 | -6001 | 295 | -2164 | 5731 | -4251 |
| Rps4x | -3555 | -300 | -4680 | 5409 | -4453 |
| Rps5 | -4284 | 1344 | -1916 | 5993 | -4583 |
| Rps6 | -4272 | 4707 | 1599 | 6014 | -5295 |
| Rps7 | -5696 | 1849 | -3387 | 6808 | -5804 |
| Rps8 | -6704 | -566 | -5243 | 7004 | -6741 |
| Rps9 | -5004 | 1757 | -844 | 6794 | -4576 |
| Rpsa | -5034 | -2245 | -4844 | 5145 | -2970 |
| Smg1 | 3917 | -8033 | -5095 | -7406 | 321 |
| Smg5 | 7469 | 3553 | 7051 | 4369 | 8104 |
| Smg6 | 6779 | 2126 | 5259 | -6151 | -687 |
| Smg7 | 2631 | -6546 | 414 | -7610 | 2309 |
| Smg8 | 4635 | 2703 | 2249 | -3912 | -2190 |
| Smg9 | 5772 | 5707 | 7473 | 5784 | 335 |
| Uba52 | -2504 | 5042 | 585 | 6605 | -5655 |
| Upf1 | 3691 | -5182 | 7561 | -6027 | 2672 |
| Upf2 | -3464 | -2789 | -5456 | 1772 | -4025 |
| Upf3a | 6309 | 4755 | 7420 | 4843 | -6023 |
| Upf3b | -5155 | 749 | -5684 | 2733 | -7352 |
COMPLEX I BIOGENESIS
| metric | value |
|---|---|
| setSize | 56 |
| pMANOVA | 3.98e-28 |
| p.adjustMANOVA | 2.29e-26 |
| s.dist | 0.971 |
| s.hyp | -0.504 |
| s.hip | 0.0518 |
| s.amy | -0.0644 |
| s.pag | 0.722 |
| s.ni | -0.402 |
| p.hyp | 6.85e-11 |
| p.hip | 0.502 |
| p.amy | 0.405 |
| p.pag | 8.79e-21 |
| p.ni | 1.9e-07 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | hyp |
|---|---|---|
| Ndufaf2 | 7198 | -7557 |
| Ndufa6 | 7289 | -6844 |
| Ndufc1 | 7415 | -6020 |
| Ndufb5 | 6768 | -6381 |
| Ndufv2 | 6958 | -6176 |
| Ndufaf5 | 5854 | -7301 |
| Tmem186 | 6454 | -6371 |
| Ndufaf6 | 6296 | -6441 |
| Ndufs5 | 7341 | -5414 |
| Ndufb8 | 7254 | -5455 |
| Ndufb1 | 7534 | -5136 |
| mt-Nd3 | 5046 | -7666 |
| Ndufb7 | 7060 | -5348 |
| Ndufb2 | 6803 | -5495 |
| Ndufb9 | 7322 | -5088 |
| Ndufs4 | 7305 | -4999 |
| Ndufb3 | 7318 | -4901 |
| Ndufa7 | 7181 | -4884 |
| Ndufa11 | 7197 | -4843 |
| Ndufb6 | 6739 | -5142 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Acad9 | -5676 | 366 | -1294 | -1492 | 6692 |
| Ecsit | -1051 | -2710 | -1024 | 3059 | 4374 |
| mt-Nd1 | -6928 | -5185 | -7660 | -3622 | -4224 |
| mt-Nd2 | -7861 | -4570 | -7273 | -8198 | -1645 |
| mt-Nd3 | -7666 | -6680 | -4666 | 5046 | -7075 |
| mt-Nd4 | -7348 | -6449 | -7717 | -6517 | -1867 |
| mt-Nd5 | -7124 | -4082 | -7797 | -7940 | 4926 |
| mt-Nd6 | -8023 | 2876 | -4700 | 100 | -6865 |
| Ndufa1 | -1642 | -1771 | 25 | 7523 | -7305 |
| Ndufa10 | -1375 | 769 | 49 | 6233 | 457 |
| Ndufa11 | -4843 | 2880 | 3522 | 7197 | -608 |
| Ndufa12 | -1267 | 1783 | -1884 | 7022 | -5851 |
| Ndufa13 | -493 | -2327 | -476 | 7372 | -6180 |
| Ndufa2 | -4537 | -3358 | 2985 | 7507 | -6445 |
| Ndufa3 | -2637 | -3209 | 4823 | 7520 | -6859 |
| Ndufa5 | -2620 | 2624 | -4109 | 7373 | -7195 |
| Ndufa6 | -6844 | 2822 | 1084 | 7289 | -7245 |
| Ndufa7 | -4884 | 3044 | 195 | 7181 | -719 |
| Ndufa8 | -3930 | 4826 | -2935 | 6143 | -2093 |
| Ndufa9 | -2068 | 488 | 2622 | 5779 | 4053 |
| Ndufab1 | -719 | -1773 | 1653 | 6967 | -4334 |
| Ndufaf1 | -5335 | 2520 | -173 | 4543 | -403 |
| Ndufaf2 | -7557 | -2229 | -89 | 7198 | -1969 |
| Ndufaf3 | 1992 | -3493 | 6320 | 6633 | -5590 |
| Ndufaf4 | -7221 | -8261 | -7354 | 3011 | -2079 |
| Ndufaf5 | -7301 | 6059 | -4640 | 5854 | 32 |
| Ndufaf6 | -6441 | -1241 | 977 | 6296 | -2306 |
| Ndufaf7 | -846 | -862 | 647 | 5389 | -1634 |
| Ndufb1 | -5136 | -4408 | 4888 | 7534 | -6898 |
| Ndufb10 | -2943 | -2704 | -955 | 6844 | -5638 |
| Ndufb11 | -5045 | 1491 | -1381 | 6729 | -6277 |
| Ndufb2 | -5495 | -3363 | -493 | 6803 | -4662 |
| Ndufb3 | -4901 | 1103 | 1115 | 7318 | -6494 |
| Ndufb4 | -4431 | 4159 | -2771 | 6606 | -1293 |
| Ndufb5 | -6381 | -2510 | 270 | 6768 | -3161 |
| Ndufb6 | -5142 | -5657 | 1899 | 6739 | -1364 |
| Ndufb7 | -5348 | 4587 | 1129 | 7060 | -5502 |
| Ndufb8 | -5455 | 591 | 1725 | 7254 | -333 |
| Ndufb9 | -5088 | -751 | 661 | 7322 | -4018 |
| Ndufc1 | -6020 | -136 | -2495 | 7415 | -6066 |
| Ndufc2 | -4295 | 417 | -4151 | 7276 | -4063 |
| Ndufs1 | 3181 | 5455 | 2072 | 1262 | 6289 |
| Ndufs2 | 449 | 1114 | 1294 | 6867 | -257 |
| Ndufs3 | -1117 | -2046 | 2011 | 6166 | -1401 |
| Ndufs4 | -4999 | 3455 | -2569 | 7305 | -2336 |
| Ndufs5 | -5414 | 852 | 1064 | 7341 | -6250 |
| Ndufs6 | -3788 | -280 | 2472 | 7369 | -6459 |
| Ndufs7 | -1023 | 4628 | -348 | 5983 | 355 |
| Ndufs8 | -2992 | 3128 | -1185 | 6711 | -1521 |
| Ndufv1 | -847 | -2170 | 5300 | 6852 | 121 |
| Ndufv2 | -6176 | 1293 | -2541 | 6958 | -2516 |
| Ndufv3 | -2781 | 4189 | 58 | 6995 | -6906 |
| Nubpl | -5005 | -3952 | -2336 | 6663 | 2142 |
| Timmdc1 | -4766 | -2177 | 3005 | 6897 | 95 |
| Tmem126b | -5439 | 2670 | -3406 | 6075 | -4984 |
| Tmem186 | -6371 | 6143 | 5973 | 6454 | -2551 |
HSF1 ACTIVATION
| metric | value |
|---|---|
| setSize | 25 |
| pMANOVA | 1.2e-07 |
| p.adjustMANOVA | 1.38e-06 |
| s.dist | 0.942 |
| s.hyp | -0.587 |
| s.hip | -0.399 |
| s.amy | -0.418 |
| s.pag | -0.186 |
| s.ni | -0.417 |
| p.hyp | 3.83e-07 |
| p.hip | 0.000547 |
| p.amy | 0.000293 |
| p.pag | 0.107 |
| p.ni | 0.000306 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | hyp | amy |
|---|---|---|
| Serpinh1 | -8169 | -7988 |
| Fkbp4 | -8071 | -7982 |
| Hsph1 | -8099 | -7948 |
| Hspa1b | -8134 | -7884 |
| Hspb1 | -8007 | -7986 |
| Hspa1a | -8073 | -7847 |
| Dnajb1 | -8118 | -7783 |
| Hsp90aa1 | -7973 | -7326 |
| Ptges3 | -7744 | -6150 |
| Dedd2 | -6503 | -6868 |
| Rpa1 | -6591 | -6403 |
| Hsp90ab1 | -7658 | -4184 |
| Mrpl18 | -5890 | -1994 |
| Rpa2 | -4626 | -2263 |
| Dnajb6 | -5164 | -1168 |
| Ywhae | -4153 | -914 |
| Eef1a1 | -4411 | -379 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Col4a6 | 7726 | 1733 | -5086 | -2425 | 2423 |
| Dedd2 | -6503 | -6839 | -6868 | -4963 | 2937 |
| Dnajb1 | -8118 | -8530 | -7783 | -7821 | -5879 |
| Dnajb6 | -5164 | 1333 | -1168 | 4244 | -3746 |
| Eef1a1 | -4411 | 2294 | -379 | 5219 | -1585 |
| Fkbp4 | -8071 | -8446 | -7982 | -4084 | -6510 |
| Hdac6 | 4648 | -5277 | 523 | -2780 | -1869 |
| Hsbp1 | -5762 | 4518 | 3646 | 6500 | -4395 |
| Hsf1 | -5123 | -2646 | 2144 | 75 | -6216 |
| Hsp90aa1 | -7973 | -8277 | -7326 | -4822 | -6162 |
| Hsp90ab1 | -7658 | -7115 | -4184 | -3700 | -6462 |
| Hspa1a | -8073 | -7910 | -7847 | -7813 | -6471 |
| Hspa1b | -8134 | -8449 | -7884 | -8270 | -6798 |
| Hspb1 | -8007 | -8589 | -7986 | -8289 | -7148 |
| Hsph1 | -8099 | -8525 | -7948 | -8014 | -6613 |
| Mrpl18 | -5890 | -1549 | -1994 | 5860 | -3037 |
| Ptges3 | -7744 | -7847 | -6150 | -2080 | -6040 |
| Rpa1 | -6591 | 136 | -6403 | 2511 | 6252 |
| Rpa2 | -4626 | 3845 | -2263 | -1754 | 4156 |
| Rpa3 | 879 | -5021 | 451 | 2729 | 6924 |
| Serpinh1 | -8169 | -8568 | -7988 | -8376 | -7457 |
| Tnfrsf21 | -435 | -6492 | 5944 | -5259 | 3980 |
| Ubb | -4378 | 3667 | 1287 | 6541 | -5290 |
| Vcp | -1766 | -4700 | 754 | -1631 | -5028 |
| Ywhae | -4153 | 1888 | -914 | 603 | -860 |
ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S
| metric | value |
|---|---|
| setSize | 59 |
| pMANOVA | 6.17e-25 |
| p.adjustMANOVA | 3.23e-23 |
| s.dist | 0.908 |
| s.hyp | -0.448 |
| s.hip | 0.0815 |
| s.amy | -0.113 |
| s.pag | 0.659 |
| s.ni | -0.412 |
| p.hyp | 2.57e-09 |
| p.hip | 0.279 |
| p.amy | 0.134 |
| p.pag | 2.03e-18 |
| p.ni | 4.51e-08 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | hyp |
|---|---|---|
| Rps23 | 6890 | -6959 |
| Rps8 | 7004 | -6704 |
| Rps12 | 7047 | -6536 |
| Rps27a | 6853 | -6372 |
| Fau | 7212 | -5907 |
| Eif3g | 6812 | -6158 |
| Rps25 | 6238 | -6573 |
| Rps27 | 7449 | -5449 |
| Rps19 | 6611 | -6105 |
| Rps15 | 7130 | -5634 |
| Eif2s1 | 5813 | -6701 |
| Rps7 | 6808 | -5696 |
| Rps10 | 7118 | -5436 |
| Rps24 | 5997 | -6377 |
| Rps11 | 6240 | -6088 |
| Rps17 | 7182 | -5260 |
| Eif3h | 6092 | -5774 |
| Rps3a1 | 5731 | -6001 |
| Eif3i | 6588 | -5204 |
| Rps21 | 7488 | -4549 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Eif1ax | -5050 | 563 | -1955 | -625 | 7369 |
| Eif2s1 | -6701 | -39 | -1217 | 5813 | 2921 |
| Eif2s2 | -4538 | -2403 | -5282 | 4050 | -5700 |
| Eif2s3x | 17 | -3878 | -3881 | -646 | 1396 |
| Eif3a | -6953 | -3944 | 1407 | -5013 | -7267 |
| Eif3b | 1168 | -6669 | 317 | 185 | 1132 |
| Eif3c | 5026 | 1285 | 6212 | 1990 | -609 |
| Eif3d | -246 | 5830 | 31 | 5012 | 3393 |
| Eif3e | -3996 | -271 | -1571 | 3711 | -2173 |
| Eif3f | -1429 | -114 | 5534 | 4747 | 1677 |
| Eif3g | -6158 | 4506 | -1026 | 6812 | -3309 |
| Eif3h | -5774 | 4130 | -1152 | 6092 | 398 |
| Eif3i | -5204 | 989 | 3667 | 6588 | 1783 |
| Eif3j1 | -933 | -3758 | -6113 | 5970 | -3553 |
| Eif3j2 | -7756 | -7169 | -7559 | -7227 | -640 |
| Eif3k | -5937 | 2750 | -2777 | 5339 | -2714 |
| Eif3l | 1203 | 1231 | 2859 | 4204 | 1293 |
| Eif3m | -3122 | 5534 | -872 | 6520 | 2334 |
| Eif4a1 | -5925 | -6104 | 4369 | 5645 | -6174 |
| Eif4a2 | -6255 | 2282 | -1778 | 4032 | 6477 |
| Eif4b | 7049 | 1455 | 4759 | -676 | 3264 |
| Eif4e | -2868 | 336 | -2621 | 4261 | 2119 |
| Eif4ebp1 | -884 | 6714 | 2834 | 3590 | -216 |
| Eif4g1 | 3439 | 953 | 4989 | -4135 | 2939 |
| Eif4h | 3731 | 704 | 3643 | 3900 | 5149 |
| Fau | -5907 | 1583 | 1608 | 7212 | -5383 |
| Pabpc1 | -4196 | -1362 | 4329 | -2356 | -620 |
| Rps10 | -5436 | 1596 | -1596 | 7118 | -2524 |
| Rps11 | -6088 | -966 | -1330 | 6240 | -6425 |
| Rps12 | -6536 | 2445 | -4827 | 7047 | -5574 |
| Rps13 | -2674 | -235 | -1978 | 6430 | -3919 |
| Rps14 | -3675 | 1734 | 3410 | 7146 | -3493 |
| Rps15 | -5634 | 2477 | 239 | 7130 | -5513 |
| Rps15a | 369 | 608 | -3369 | 6779 | -5204 |
| Rps16 | -4792 | 2799 | -1537 | 6267 | -5455 |
| Rps17 | -5260 | -1557 | 1246 | 7182 | -6746 |
| Rps18 | -4838 | 1158 | 194 | 6830 | -4753 |
| Rps19 | -6105 | -2857 | -5576 | 6611 | -5782 |
| Rps2 | -2017 | 387 | -812 | 6266 | -3726 |
| Rps20 | -4819 | -1197 | -4402 | 5625 | -7090 |
| Rps21 | -4549 | -3950 | -722 | 7488 | -7191 |
| Rps23 | -6959 | 2961 | -3533 | 6890 | -7067 |
| Rps24 | -6377 | -301 | -5394 | 5997 | -5015 |
| Rps25 | -6573 | -1150 | -1883 | 6238 | -5538 |
| Rps26 | -5325 | 3572 | -3697 | 5769 | -6007 |
| Rps27 | -5449 | -2098 | 2068 | 7449 | -7364 |
| Rps27a | -6372 | -7132 | -2043 | 6853 | -6401 |
| Rps27l | -4990 | -3246 | -4325 | 6048 | -3758 |
| Rps28 | -2854 | -2799 | 2837 | 7397 | -7470 |
| Rps29 | -234 | -4717 | -446 | 7482 | -7465 |
| Rps3 | -5535 | 1738 | -2705 | 6117 | -1500 |
| Rps3a1 | -6001 | 295 | -2164 | 5731 | -4251 |
| Rps4x | -3555 | -300 | -4680 | 5409 | -4453 |
| Rps5 | -4284 | 1344 | -1916 | 5993 | -4583 |
| Rps6 | -4272 | 4707 | 1599 | 6014 | -5295 |
| Rps7 | -5696 | 1849 | -3387 | 6808 | -5804 |
| Rps8 | -6704 | -566 | -5243 | 7004 | -6741 |
| Rps9 | -5004 | 1757 | -844 | 6794 | -4576 |
| Rpsa | -5034 | -2245 | -4844 | 5145 | -2970 |
MITOCHONDRIAL TRANSLATION
| metric | value |
|---|---|
| setSize | 93 |
| pMANOVA | 8.92e-39 |
| p.adjustMANOVA | 5.71e-37 |
| s.dist | 0.893 |
| s.hyp | -0.317 |
| s.hip | 0.256 |
| s.amy | -0.0359 |
| s.pag | 0.748 |
| s.ni | -0.267 |
| p.hyp | 1.24e-07 |
| p.hip | 2.01e-05 |
| p.amy | 0.55 |
| p.pag | 9.42e-36 |
| p.ni | 8.92e-06 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | hyp |
|---|---|---|
| Mrps18c | 7176 | -7065 |
| Mrps28 | 7418 | -6811 |
| Mrpl14 | 6661 | -7286 |
| Mrpl53 | 7284 | -6639 |
| Mrpl20 | 7258 | -6519 |
| Mrps7 | 6239 | -7344 |
| Mrpl46 | 6237 | -7085 |
| Mrpl52 | 7390 | -5954 |
| Mrps22 | 5476 | -7948 |
| Mrpl48 | 6942 | -6124 |
| Mrpl33 | 6503 | -6497 |
| Gadd45gip1 | 7248 | -5657 |
| Mrpl13 | 6553 | -6207 |
| Mrrf | 5073 | -7772 |
| Mrpl12 | 6609 | -5882 |
| Mrpl57 | 6037 | -6419 |
| Tsfm | 6095 | -6083 |
| Mrpl11 | 6839 | -5254 |
| Mrpl28 | 6773 | -5222 |
| Mrpl18 | 5860 | -5890 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Aurkaip1 | -3086 | 3022 | 42 | 6936 | -4705 |
| Chchd1 | -4961 | 1272 | -3652 | 4586 | -4442 |
| Dap3 | -1253 | -4822 | 1211 | 3216 | -3270 |
| Eral1 | -4952 | 934 | 643 | 4929 | 3792 |
| Gadd45gip1 | -5657 | 6927 | -2559 | 7248 | -6665 |
| Gfm1 | -2018 | -937 | 1527 | 1626 | 6987 |
| Gfm2 | 1062 | -7473 | -3525 | -6490 | -3291 |
| Mrpl1 | 992 | 5947 | -2443 | 6649 | 5258 |
| Mrpl10 | 1879 | 1361 | -2761 | 4599 | -1740 |
| Mrpl11 | -5254 | 5334 | 1665 | 6839 | -3134 |
| Mrpl12 | -5882 | 4072 | -2217 | 6609 | -276 |
| Mrpl13 | -6207 | 2695 | -1459 | 6553 | -5019 |
| Mrpl14 | -7286 | -119 | 1512 | 6661 | -4211 |
| Mrpl15 | -2305 | 1549 | 863 | 6178 | 4693 |
| Mrpl16 | -1284 | 5083 | 2305 | 5753 | -2518 |
| Mrpl17 | -1714 | 3409 | 3223 | 5890 | 1456 |
| Mrpl18 | -5890 | -1549 | -1994 | 5860 | -3037 |
| Mrpl19 | 596 | -6654 | -4785 | 4294 | 663 |
| Mrpl2 | 1870 | 1052 | 3513 | 7315 | -2532 |
| Mrpl20 | -6519 | 2377 | 2323 | 7258 | -3749 |
| Mrpl21 | -2110 | 5249 | -981 | 6671 | -4232 |
| Mrpl22 | -2060 | 2064 | -5366 | 5105 | -5899 |
| Mrpl23 | 4859 | 6608 | 7517 | 6345 | 5644 |
| Mrpl24 | -3031 | -2024 | -898 | 3526 | -4571 |
| Mrpl27 | -4208 | 5727 | 2391 | 6774 | -4936 |
| Mrpl28 | -5222 | -318 | 115 | 6773 | -3335 |
| Mrpl3 | 1174 | 5406 | 2209 | 4493 | 5245 |
| Mrpl30 | -4723 | -7449 | -4961 | 7085 | -4843 |
| Mrpl32 | -744 | 1078 | -2106 | 5355 | -5809 |
| Mrpl33 | -6497 | 1202 | -4073 | 6503 | -5647 |
| Mrpl34 | -4227 | 4066 | 1161 | 6463 | 664 |
| Mrpl35 | -4084 | -7926 | -2449 | 6136 | -3332 |
| Mrpl36 | 1669 | -4014 | -3043 | 5490 | 899 |
| Mrpl37 | -4200 | -2415 | 6182 | 3310 | -2662 |
| Mrpl38 | -5630 | -1707 | -140 | 5052 | 5520 |
| Mrpl39 | -2052 | -2049 | -2448 | 6571 | 4690 |
| Mrpl4 | 2848 | -3719 | 587 | 4090 | 4241 |
| Mrpl40 | -1688 | -635 | 2112 | 6926 | -149 |
| Mrpl41 | -1196 | 4119 | -114 | 7186 | -2810 |
| Mrpl42 | -4711 | 1149 | -1566 | 6210 | -5136 |
| Mrpl43 | 2128 | 6123 | 3105 | 6914 | -1411 |
| Mrpl44 | -330 | 1775 | -2714 | 6957 | -236 |
| Mrpl46 | -7085 | 4523 | 2912 | 6237 | 715 |
| Mrpl47 | -5944 | 2207 | -1391 | 4451 | -6722 |
| Mrpl48 | -6124 | -2533 | -1624 | 6942 | -1540 |
| Mrpl49 | -2365 | 5073 | -1722 | 6491 | 4270 |
| Mrpl50 | -1198 | 1058 | -5051 | 4751 | -72 |
| Mrpl51 | -4570 | 404 | -5422 | 7040 | -4837 |
| Mrpl52 | -5954 | 1977 | -1130 | 7390 | -7235 |
| Mrpl53 | -6639 | 1342 | 2774 | 7284 | 1770 |
| Mrpl54 | -2430 | 6666 | 1091 | 7299 | -113 |
| Mrpl55 | -1268 | 4941 | 3529 | 6330 | -3406 |
| Mrpl57 | -6419 | 3753 | 294 | 6037 | -1433 |
| Mrpl58 | -644 | 7271 | -505 | 7526 | -1114 |
| Mrpl9 | 4967 | -648 | 5546 | 6962 | 8185 |
| Mrps10 | -1298 | 2599 | 1556 | 6347 | -6188 |
| Mrps11 | -3356 | 4316 | -4616 | 4464 | -2541 |
| Mrps12 | -4618 | -969 | -2510 | 7009 | -1687 |
| Mrps14 | -4998 | 3422 | -1075 | 6290 | -4505 |
| Mrps15 | 3255 | 4779 | 5761 | 6181 | -7028 |
| Mrps16 | -3689 | -728 | 3672 | 7136 | -2981 |
| Mrps17 | -3198 | -4205 | 721 | 6176 | -2111 |
| Mrps18a | -5153 | 773 | 375 | 5147 | -4985 |
| Mrps18b | 1882 | 4699 | 6568 | 5615 | 3311 |
| Mrps18c | -7065 | 5718 | 1280 | 7176 | -4449 |
| Mrps2 | -5187 | 3643 | -3063 | 3194 | -1712 |
| Mrps21 | -1319 | -1469 | -1393 | 7411 | -6422 |
| Mrps22 | -7948 | 2226 | -3386 | 5476 | 27 |
| Mrps23 | -1105 | 2061 | 446 | 6563 | 1203 |
| Mrps24 | -3065 | 4540 | -715 | 6986 | -5226 |
| Mrps25 | -2151 | -2197 | 1641 | 4566 | -4358 |
| Mrps26 | -2660 | 6707 | 1526 | 7237 | -2044 |
| Mrps27 | -2279 | 2536 | 5187 | 6772 | 2400 |
| Mrps28 | -6811 | 5250 | -284 | 7418 | 4481 |
| Mrps30 | -1493 | -76 | -340 | 2793 | 7545 |
| Mrps31 | -2956 | 5290 | -6391 | 1471 | -6530 |
| Mrps33 | -3032 | 2817 | 2967 | 7164 | -5463 |
| Mrps34 | -1524 | 5391 | 4883 | 7215 | -2980 |
| Mrps35 | -4109 | -2386 | -4247 | 5154 | -5105 |
| Mrps36 | -528 | 1971 | -5580 | 6482 | -2136 |
| Mrps5 | -3252 | 4678 | -5618 | 1452 | -3187 |
| Mrps6 | -6365 | -347 | -3933 | 5125 | -5302 |
| Mrps7 | -7344 | 2502 | -1725 | 6239 | -3589 |
| Mrps9 | -2595 | 4672 | -159 | 6221 | -6523 |
| Mrrf | -7772 | 1183 | -3588 | 5073 | 2464 |
| Mtfmt | 1689 | -5402 | 6027 | 5724 | -7073 |
| Mtif2 | 4688 | 4640 | -1816 | 4425 | -3488 |
| Mtif3 | -1214 | -341 | 2008 | 4991 | -1724 |
| Mtrf1l | -1708 | -2289 | -7824 | -4404 | -4230 |
| Oxa1l | 2952 | 3978 | 5784 | 2108 | 7131 |
| Ptcd3 | -2581 | -4130 | -1696 | 1339 | 1168 |
| Tsfm | -6083 | -3471 | -166 | 6095 | -696 |
| Tufm | 2 | -3435 | -3801 | 3887 | -1319 |
RESPIRATORY ELECTRON TRANSPORT
| metric | value |
|---|---|
| setSize | 102 |
| pMANOVA | 1.1e-43 |
| p.adjustMANOVA | 9.74e-42 |
| s.dist | 0.882 |
| s.hyp | -0.44 |
| s.hip | 0.0842 |
| s.amy | -0.0591 |
| s.pag | 0.697 |
| s.ni | -0.298 |
| p.hyp | 1.7e-14 |
| p.hip | 0.142 |
| p.amy | 0.302 |
| p.pag | 3.7e-34 |
| p.ni | 2.11e-07 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | hyp |
|---|---|---|
| Ndufaf2 | 7198 | -7557 |
| Ndufa6 | 7289 | -6844 |
| Ndufc1 | 7415 | -6020 |
| Ndufb5 | 6768 | -6381 |
| Ndufv2 | 6958 | -6176 |
| Uqcr10 | 7414 | -5777 |
| Ndufaf5 | 5854 | -7301 |
| Ndufa4 | 7443 | -5550 |
| Tmem186 | 6454 | -6371 |
| Cox16 | 6517 | -6282 |
| Ndufaf6 | 6296 | -6441 |
| Uqcrh | 7167 | -5590 |
| Ndufs5 | 7341 | -5414 |
| Ndufb8 | 7254 | -5455 |
| Ndufb1 | 7534 | -5136 |
| mt-Nd3 | 5046 | -7666 |
| Ndufb7 | 7060 | -5348 |
| Ndufb2 | 6803 | -5495 |
| Ndufb9 | 7322 | -5088 |
| Ndufs4 | 7305 | -4999 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Acad9 | -5676 | 366 | -1294 | -1492 | 6692 |
| Coq10a | -872 | 174 | 5512 | 5642 | 391 |
| Coq10b | -6767 | -4385 | -6656 | -1657 | 4691 |
| Cox11 | -5932 | 7313 | 440 | 3726 | 8009 |
| Cox14 | 706 | 4447 | -776 | 7356 | -1516 |
| Cox16 | -6282 | 2257 | -655 | 6517 | -6680 |
| Cox18 | -3104 | -1376 | 5803 | 3205 | -3296 |
| Cox19 | -5148 | -5349 | 3732 | 5991 | 873 |
| Cox20 | -1044 | 4893 | -7512 | 6453 | -7393 |
| Cox4i1 | -3460 | -1188 | 515 | 7220 | -2439 |
| Cox5a | -4271 | 1133 | 261 | 7346 | -4824 |
| Cox5b | -2705 | 2950 | 1495 | 7376 | -6255 |
| Cox6a1 | -1788 | 328 | -119 | 7216 | -4900 |
| Cox6b1 | -3261 | -444 | 1867 | 7386 | -3016 |
| Cox6c | -4918 | -2459 | -1646 | 7401 | -6749 |
| Cox7a2l | -4693 | 1079 | -1681 | 6310 | -3384 |
| Cox7b | -4523 | 1796 | 982 | 7333 | -4507 |
| Cox7c | -4742 | -5409 | -360 | 7511 | -6259 |
| Cox8a | -2866 | -1850 | 3090 | 7510 | -4137 |
| Cyc1 | -2233 | 4850 | 3117 | 7172 | 3586 |
| Cycs | -4981 | -5765 | -4663 | 5515 | -1835 |
| Ecsit | -1051 | -2710 | -1024 | 3059 | 4374 |
| Etfa | -752 | 6447 | -2498 | 4988 | 3243 |
| Etfb | -1476 | 2943 | -3519 | 6573 | -4684 |
| Etfdh | -2121 | -2201 | 843 | 4969 | 4804 |
| Lrpprc | 4844 | 219 | 3885 | -1624 | 4485 |
| mt-Co1 | -6566 | -5691 | -7888 | -4846 | 3504 |
| mt-Co2 | -6934 | -6438 | -7852 | -408 | -6525 |
| mt-Co3 | -7004 | -7097 | -7148 | 3668 | -3117 |
| mt-Cytb | -6223 | -5636 | -7841 | -2825 | -4086 |
| mt-Nd1 | -6928 | -5185 | -7660 | -3622 | -4224 |
| mt-Nd2 | -7861 | -4570 | -7273 | -8198 | -1645 |
| mt-Nd3 | -7666 | -6680 | -4666 | 5046 | -7075 |
| mt-Nd4 | -7348 | -6449 | -7717 | -6517 | -1867 |
| mt-Nd5 | -7124 | -4082 | -7797 | -7940 | 4926 |
| mt-Nd6 | -8023 | 2876 | -4700 | 100 | -6865 |
| Ndufa1 | -1642 | -1771 | 25 | 7523 | -7305 |
| Ndufa10 | -1375 | 769 | 49 | 6233 | 457 |
| Ndufa11 | -4843 | 2880 | 3522 | 7197 | -608 |
| Ndufa12 | -1267 | 1783 | -1884 | 7022 | -5851 |
| Ndufa13 | -493 | -2327 | -476 | 7372 | -6180 |
| Ndufa2 | -4537 | -3358 | 2985 | 7507 | -6445 |
| Ndufa3 | -2637 | -3209 | 4823 | 7520 | -6859 |
| Ndufa4 | -5550 | 879 | 695 | 7443 | -6311 |
| Ndufa5 | -2620 | 2624 | -4109 | 7373 | -7195 |
| Ndufa6 | -6844 | 2822 | 1084 | 7289 | -7245 |
| Ndufa7 | -4884 | 3044 | 195 | 7181 | -719 |
| Ndufa8 | -3930 | 4826 | -2935 | 6143 | -2093 |
| Ndufa9 | -2068 | 488 | 2622 | 5779 | 4053 |
| Ndufab1 | -719 | -1773 | 1653 | 6967 | -4334 |
| Ndufaf1 | -5335 | 2520 | -173 | 4543 | -403 |
| Ndufaf2 | -7557 | -2229 | -89 | 7198 | -1969 |
| Ndufaf3 | 1992 | -3493 | 6320 | 6633 | -5590 |
| Ndufaf4 | -7221 | -8261 | -7354 | 3011 | -2079 |
| Ndufaf5 | -7301 | 6059 | -4640 | 5854 | 32 |
| Ndufaf6 | -6441 | -1241 | 977 | 6296 | -2306 |
| Ndufaf7 | -846 | -862 | 647 | 5389 | -1634 |
| Ndufb1 | -5136 | -4408 | 4888 | 7534 | -6898 |
| Ndufb10 | -2943 | -2704 | -955 | 6844 | -5638 |
| Ndufb11 | -5045 | 1491 | -1381 | 6729 | -6277 |
| Ndufb2 | -5495 | -3363 | -493 | 6803 | -4662 |
| Ndufb3 | -4901 | 1103 | 1115 | 7318 | -6494 |
| Ndufb4 | -4431 | 4159 | -2771 | 6606 | -1293 |
| Ndufb5 | -6381 | -2510 | 270 | 6768 | -3161 |
| Ndufb6 | -5142 | -5657 | 1899 | 6739 | -1364 |
| Ndufb7 | -5348 | 4587 | 1129 | 7060 | -5502 |
| Ndufb8 | -5455 | 591 | 1725 | 7254 | -333 |
| Ndufb9 | -5088 | -751 | 661 | 7322 | -4018 |
| Ndufc1 | -6020 | -136 | -2495 | 7415 | -6066 |
| Ndufc2 | -4295 | 417 | -4151 | 7276 | -4063 |
| Ndufs1 | 3181 | 5455 | 2072 | 1262 | 6289 |
| Ndufs2 | 449 | 1114 | 1294 | 6867 | -257 |
| Ndufs3 | -1117 | -2046 | 2011 | 6166 | -1401 |
| Ndufs4 | -4999 | 3455 | -2569 | 7305 | -2336 |
| Ndufs5 | -5414 | 852 | 1064 | 7341 | -6250 |
| Ndufs6 | -3788 | -280 | 2472 | 7369 | -6459 |
| Ndufs7 | -1023 | 4628 | -348 | 5983 | 355 |
| Ndufs8 | -2992 | 3128 | -1185 | 6711 | -1521 |
| Ndufv1 | -847 | -2170 | 5300 | 6852 | 121 |
| Ndufv2 | -6176 | 1293 | -2541 | 6958 | -2516 |
| Ndufv3 | -2781 | 4189 | 58 | 6995 | -6906 |
| Nubpl | -5005 | -3952 | -2336 | 6663 | 2142 |
| Sco1 | 6003 | 3379 | -1586 | -23 | -4234 |
| Sco2 | -4440 | 7309 | -4790 | 2005 | 3240 |
| Sdha | 1625 | 412 | -402 | -307 | 2983 |
| Sdhb | -3060 | 1036 | 4033 | 6049 | 2667 |
| Sdhc | -3701 | 1262 | -4103 | 4609 | 2812 |
| Sdhd | -1537 | -1697 | 3628 | 7189 | 6034 |
| Surf1 | -295 | 6094 | -2113 | 6860 | 2659 |
| Taco1 | -2002 | 843 | 2808 | -4123 | 7664 |
| Timmdc1 | -4766 | -2177 | 3005 | 6897 | 95 |
| Tmem126b | -5439 | 2670 | -3406 | 6075 | -4984 |
| Tmem186 | -6371 | 6143 | 5973 | 6454 | -2551 |
| Trap1 | 3061 | 3914 | 4469 | 4129 | 8176 |
| Uqcr10 | -5777 | 2680 | 4091 | 7414 | -4487 |
| Uqcr11 | -2063 | -1401 | 976 | 7430 | -5850 |
| Uqcrb | -3491 | -4744 | 1751 | 7153 | -5743 |
| Uqcrc1 | -3385 | 3074 | 2069 | 7101 | 2064 |
| Uqcrc2 | -3878 | 2883 | -1300 | 5852 | 5995 |
| Uqcrfs1 | -1882 | 3351 | 1810 | 6908 | 2495 |
| Uqcrh | -5590 | 1885 | -1120 | 7167 | -1739 |
| Uqcrq | -4697 | -513 | -713 | 7472 | -5260 |
ADENYLATE CYCLASE ACTIVATING PATHWAY
| metric | value |
|---|---|
| setSize | 10 |
| pMANOVA | 0.00118 |
| p.adjustMANOVA | 0.00497 |
| s.dist | 0.875 |
| s.hyp | 0.302 |
| s.hip | -0.261 |
| s.amy | 0.177 |
| s.pag | -0.736 |
| s.ni | 0.18 |
| p.hyp | 0.0983 |
| p.hip | 0.153 |
| p.amy | 0.332 |
| p.pag | 5.54e-05 |
| p.ni | 0.323 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | hyp |
|---|---|---|
| Adcy5 | -7109 | 5698 |
| Gnal | -6523 | 6117 |
| Adcy2 | -5988 | 5238 |
| Adcy6 | -8137 | 3415 |
| Adcy7 | -8304 | 2896 |
| Adcy3 | -7195 | 2809 |
| Adcy9 | -4061 | 4621 |
| Adcy1 | -569 | 6550 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Adcy1 | 6550 | -5883 | 1481 | -569 | 7791 |
| Adcy2 | 5238 | -6343 | 5164 | -5988 | 4022 |
| Adcy3 | 2809 | -8015 | 5837 | -7195 | 2370 |
| Adcy4 | -7925 | -7008 | -6394 | -8405 | -6896 |
| Adcy5 | 5698 | 1302 | 4984 | -7109 | 2333 |
| Adcy6 | 3415 | -2399 | 428 | -8137 | -2772 |
| Adcy7 | 2896 | 1967 | -689 | -8304 | 5066 |
| Adcy8 | -7137 | 349 | -3569 | -6760 | -2592 |
| Adcy9 | 4621 | -3268 | 6495 | -4061 | 4438 |
| Gnal | 6117 | 2185 | 443 | -6523 | 5570 |
MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS
| metric | value |
|---|---|
| setSize | 13 |
| pMANOVA | 0.000223 |
| p.adjustMANOVA | 0.00118 |
| s.dist | 0.867 |
| s.hyp | -0.398 |
| s.hip | 0.221 |
| s.amy | -0.161 |
| s.pag | 0.631 |
| s.ni | -0.349 |
| p.hyp | 0.0129 |
| p.hip | 0.169 |
| p.amy | 0.314 |
| p.pag | 8.26e-05 |
| p.ni | 0.0295 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | hyp |
|---|---|---|
| Fdx1 | 6415 | -8058 |
| Lyrm4 | 6845 | -6982 |
| Fxn | 6236 | -7245 |
| Slc25a28 | 3934 | -7502 |
| Iscu | 5975 | -4062 |
| Glrx5 | 6734 | -3215 |
| Fdxr | 4484 | -4599 |
| Hscb | 5971 | -1232 |
| Isca2 | 4233 | -1561 |
| Nfs1 | 5681 | -697 |
| Fdx2 | 5881 | -436 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Fdx1 | -8058 | -4624 | 2558 | 6415 | -4440 |
| Fdx2 | -436 | 605 | 1510 | 5881 | -4668 |
| Fdxr | -4599 | -3512 | -5745 | 4484 | -2693 |
| Fxn | -7245 | 3296 | -7061 | 6236 | -4353 |
| Glrx5 | -3215 | 3846 | -912 | 6734 | -4911 |
| Hscb | -1232 | -1359 | 412 | 5971 | 3881 |
| Isca1 | 1604 | -2045 | -5126 | 4994 | 3655 |
| Isca2 | -1561 | 5953 | -524 | 4233 | -5852 |
| Iscu | -4062 | 4877 | -3860 | 5975 | -3034 |
| Lyrm4 | -6982 | 4014 | -1683 | 6845 | -4536 |
| Nfs1 | -697 | 6247 | 2962 | 5681 | -602 |
| Slc25a28 | -7502 | -200 | 2247 | 3934 | -6708 |
| Slc25a37 | 248 | -2360 | -1480 | -7456 | 4461 |
REGULATION OF EXPRESSION OF SLITS AND ROBOS
| metric | value |
|---|---|
| setSize | 159 |
| pMANOVA | 1.64e-62 |
| p.adjustMANOVA | 3.77e-60 |
| s.dist | 0.866 |
| s.hyp | -0.413 |
| s.hip | 0.0693 |
| s.amy | -0.0752 |
| s.pag | 0.593 |
| s.ni | -0.466 |
| p.hyp | 2.84e-19 |
| p.hip | 0.132 |
| p.amy | 0.102 |
| p.pag | 3.09e-38 |
| p.ni | 3.43e-24 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | ni |
|---|---|---|
| Rps29 | 7482 | -7465 |
| Rpl38 | 7427 | -7458 |
| Rps28 | 7397 | -7470 |
| Rpl39 | 7435 | -7398 |
| Rps27 | 7449 | -7364 |
| Rps21 | 7488 | -7191 |
| Rpl37a | 7353 | -7233 |
| Rpl37 | 7169 | -7308 |
| Rpl23 | 6983 | -7403 |
| Rpl35a | 7450 | -6779 |
| Rpl36al | 7142 | -7041 |
| Rpl35 | 7203 | -6944 |
| Rps23 | 6890 | -7067 |
| Rps17 | 7182 | -6746 |
| Rpl36a | 6846 | -6933 |
| Rps8 | 7004 | -6741 |
| Rpl30 | 6489 | -7269 |
| Rpl21 | 6613 | -7105 |
| Rpl31 | 7055 | -6596 |
| Sem1 | 6969 | -6676 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Casc3 | 4984 | -4302 | 1439 | -5352 | 371 |
| Col4a5 | -3232 | -4673 | 1386 | -5890 | -2276 |
| Cul2 | -6654 | -515 | -1156 | 1450 | 2026 |
| Dag1 | -866 | -1433 | -3459 | -6302 | 4086 |
| Eif4a3 | 1584 | 3787 | 6555 | 6201 | -4877 |
| Eif4g1 | 3439 | 953 | 4989 | -4135 | 2939 |
| Elob | -4620 | 2590 | -1125 | 5610 | -6996 |
| Eloc | -6626 | 458 | -2989 | 5900 | 190 |
| Etf1 | -4514 | -1719 | -5831 | 2237 | 745 |
| Fau | -5907 | 1583 | 1608 | 7212 | -5383 |
| Gspt1 | 1609 | -582 | -4047 | -5342 | 6563 |
| Gspt2 | -5177 | 6055 | 689 | -4954 | -1529 |
| Ldb1 | 1262 | -2548 | 5905 | -492 | -5188 |
| Lhx2 | 7722 | 1201 | -528 | -8323 | -2401 |
| Lhx9 | 1585 | 4716 | -7335 | -8123 | -3999 |
| Magoh | -6703 | -2382 | 1798 | 7239 | -4713 |
| Magohb | -8083 | -7545 | 1819 | 6954 | -6268 |
| Msi1 | -732 | -116 | -626 | -5345 | -5783 |
| Ncbp1 | 472 | -1721 | 5922 | 1206 | 2493 |
| Ncbp2 | -2016 | 5799 | 659 | 5157 | -5666 |
| Pabpc1 | -4196 | -1362 | 4329 | -2356 | -620 |
| Psma1 | -7420 | -4010 | -2108 | 4832 | 1858 |
| Psma2 | -5644 | 3865 | -2900 | 6209 | 1865 |
| Psma3 | -6066 | 979 | -2046 | 7155 | -4041 |
| Psma4 | -7504 | 977 | 368 | 6831 | -5642 |
| Psma5 | -2124 | -1232 | 2483 | 4725 | 2300 |
| Psma6 | -5994 | 3421 | -370 | 6511 | 835 |
| Psma7 | -6285 | 2069 | 2339 | 6865 | 571 |
| Psmb1 | -5858 | -1406 | -2701 | 5823 | -2062 |
| Psmb10 | -3492 | 4071 | 526 | 5974 | -4727 |
| Psmb2 | -634 | 4648 | 5325 | 7007 | 830 |
| Psmb3 | -6332 | -4121 | 2181 | 7151 | -84 |
| Psmb4 | -4320 | 1432 | -1045 | 6715 | -3833 |
| Psmb5 | -3602 | 1198 | 3279 | 7354 | -522 |
| Psmb6 | -5672 | -1356 | -959 | 6933 | -4272 |
| Psmb7 | -1170 | 1445 | 2791 | 7138 | -1108 |
| Psmb8 | -4080 | -6385 | -7753 | 1678 | -7164 |
| Psmb9 | -4395 | 2842 | -6017 | -1361 | -6203 |
| Psmc1 | -3306 | -2805 | 3510 | 5660 | -2811 |
| Psmc2 | -6518 | 3638 | 311 | 5333 | 14 |
| Psmc3 | -2810 | -6533 | 330 | 5063 | -1709 |
| Psmc4 | -1805 | -523 | 3727 | 6567 | -1984 |
| Psmc5 | -3339 | 1551 | -4032 | 5126 | -3280 |
| Psmc6 | -6889 | -1882 | -5077 | 3383 | 2777 |
| Psmd1 | -6211 | -4112 | 2043 | 1517 | 1743 |
| Psmd10 | -5057 | 5662 | -811 | 3277 | 1494 |
| Psmd11 | -3954 | -7414 | -6745 | -3634 | -2989 |
| Psmd12 | -7136 | -641 | -4440 | 3580 | -1003 |
| Psmd13 | -420 | 3420 | 1880 | 6754 | -3079 |
| Psmd14 | -6510 | -4665 | 1516 | 5163 | 1500 |
| Psmd2 | 5901 | -1504 | 6553 | -254 | 4336 |
| Psmd3 | 6 | -1368 | 4418 | 6572 | -1820 |
| Psmd4 | -3476 | -556 | 3530 | 4997 | -899 |
| Psmd5 | -7412 | -4455 | -6171 | -4153 | 7500 |
| Psmd6 | -5055 | -1678 | -1384 | 2086 | 1811 |
| Psmd7 | 88 | -5762 | 6557 | 6395 | -2888 |
| Psmd8 | -1002 | 758 | 5775 | 5963 | -933 |
| Psmd9 | -869 | -4765 | -1399 | 6885 | -2353 |
| Psme1 | -4847 | 4903 | 2140 | 6188 | -6113 |
| Psme2 | -5948 | -131 | -860 | 4745 | -6182 |
| Psme3 | 2209 | -3777 | 5865 | -3604 | 6598 |
| Psme4 | 6160 | -6527 | -5452 | -4504 | 4226 |
| Psmf1 | 2377 | 3789 | 7161 | 2699 | 6535 |
| Rbm8a | -7955 | -5212 | -6869 | 2235 | -7128 |
| Rbx1 | 234 | -1186 | -2007 | 6309 | -3980 |
| Rnps1 | -2423 | 1730 | 4062 | 1254 | -2459 |
| Robo1 | -2715 | -456 | -179 | -7831 | 6091 |
| Robo2 | 6889 | -5001 | 6428 | -4801 | 7272 |
| Robo3 | 6257 | -7159 | 4337 | -6539 | -164 |
| Rpl10 | 7552 | 2305 | -6483 | 1980 | 1798 |
| Rpl10a | -4754 | 5887 | -3904 | 6315 | -6264 |
| Rpl11 | -7040 | -1610 | -1752 | 7106 | -5100 |
| Rpl12 | -1293 | 111 | -1276 | 5593 | -4815 |
| Rpl13 | -5435 | 705 | -309 | 7111 | -4751 |
| Rpl13a | -6127 | -800 | -4926 | 6137 | -3678 |
| Rpl14 | -4973 | 3377 | -3827 | 6231 | -6184 |
| Rpl15 | -1081 | 4664 | -97 | 5670 | -5225 |
| Rpl17 | -6154 | 1812 | -4356 | 5972 | -3587 |
| Rpl18 | -3623 | 1407 | 1250 | 6814 | -5632 |
| Rpl18a | -1090 | 3984 | -5189 | 6777 | -4423 |
| Rpl19 | -6145 | 1844 | 1393 | 7139 | -5256 |
| Rpl21 | -5242 | 1494 | -2632 | 6613 | -7105 |
| Rpl22 | 2309 | 1493 | 135 | 7361 | -5393 |
| Rpl22l1 | -6274 | -4977 | -2367 | 6270 | -5683 |
| Rpl23 | -4886 | -1314 | -5284 | 6983 | -7403 |
| Rpl23a | -5685 | 181 | -4668 | 5986 | -6814 |
| Rpl24 | -6576 | 1391 | -3886 | 6934 | -6380 |
| Rpl26 | -6659 | 1690 | -587 | 7025 | -6436 |
| Rpl27 | -6845 | 1737 | -3419 | 6972 | -3911 |
| Rpl27a | -5517 | 3660 | -2513 | 5849 | -4735 |
| Rpl28 | -1279 | 5641 | -1248 | 5705 | -5460 |
| Rpl29 | -1125 | 4140 | -4187 | 6593 | -5922 |
| Rpl3 | -4393 | 97 | 1158 | 6008 | -4443 |
| Rpl30 | -3489 | -1769 | -4305 | 6489 | -7269 |
| Rpl31 | -6836 | -3203 | -1412 | 7055 | -6596 |
| Rpl32 | -4734 | -2231 | 1048 | 7325 | -5634 |
| Rpl34 | -5472 | -4039 | -1304 | 7052 | -5665 |
| Rpl35 | -5746 | -5044 | -3769 | 7203 | -6944 |
| Rpl35a | -5482 | -3840 | 570 | 7450 | -6779 |
| Rpl36 | -4150 | -526 | -925 | 7394 | -6244 |
| Rpl36a | -5737 | 966 | -3217 | 6846 | -6933 |
| Rpl36al | -5513 | 1911 | -471 | 7142 | -7041 |
| Rpl37 | -4803 | -2009 | -157 | 7169 | -7308 |
| Rpl37a | -5196 | -2693 | 70 | 7353 | -7233 |
| Rpl38 | -4285 | -3890 | 857 | 7427 | -7458 |
| Rpl39 | -6226 | -2451 | 1477 | 7435 | -7398 |
| Rpl4 | -4925 | 1852 | -4074 | 6135 | -4712 |
| Rpl5 | 5744 | -2476 | -3141 | 5665 | 42 |
| Rpl6 | -5411 | 5527 | -1164 | 5021 | -4217 |
| Rpl7 | -5113 | 1762 | 151 | 6242 | -4040 |
| Rpl7a | -3564 | 4076 | 1931 | 6938 | -2667 |
| Rpl8 | -3703 | 3543 | -3664 | 6481 | -4491 |
| Rpl9 | -5504 | 344 | 903 | 6756 | -2526 |
| Rplp0 | -3763 | 4412 | -942 | 6357 | 956 |
| Rplp1 | -3659 | -3603 | -814 | 6990 | -6512 |
| Rplp2 | -1405 | 721 | 5081 | 7200 | -5799 |
| Rps10 | -5436 | 1596 | -1596 | 7118 | -2524 |
| Rps11 | -6088 | -966 | -1330 | 6240 | -6425 |
| Rps12 | -6536 | 2445 | -4827 | 7047 | -5574 |
| Rps13 | -2674 | -235 | -1978 | 6430 | -3919 |
| Rps14 | -3675 | 1734 | 3410 | 7146 | -3493 |
| Rps15 | -5634 | 2477 | 239 | 7130 | -5513 |
| Rps15a | 369 | 608 | -3369 | 6779 | -5204 |
| Rps16 | -4792 | 2799 | -1537 | 6267 | -5455 |
| Rps17 | -5260 | -1557 | 1246 | 7182 | -6746 |
| Rps18 | -4838 | 1158 | 194 | 6830 | -4753 |
| Rps19 | -6105 | -2857 | -5576 | 6611 | -5782 |
| Rps2 | -2017 | 387 | -812 | 6266 | -3726 |
| Rps20 | -4819 | -1197 | -4402 | 5625 | -7090 |
| Rps21 | -4549 | -3950 | -722 | 7488 | -7191 |
| Rps23 | -6959 | 2961 | -3533 | 6890 | -7067 |
| Rps24 | -6377 | -301 | -5394 | 5997 | -5015 |
| Rps25 | -6573 | -1150 | -1883 | 6238 | -5538 |
| Rps26 | -5325 | 3572 | -3697 | 5769 | -6007 |
| Rps27 | -5449 | -2098 | 2068 | 7449 | -7364 |
| Rps27a | -6372 | -7132 | -2043 | 6853 | -6401 |
| Rps27l | -4990 | -3246 | -4325 | 6048 | -3758 |
| Rps28 | -2854 | -2799 | 2837 | 7397 | -7470 |
| Rps29 | -234 | -4717 | -446 | 7482 | -7465 |
| Rps3 | -5535 | 1738 | -2705 | 6117 | -1500 |
| Rps3a1 | -6001 | 295 | -2164 | 5731 | -4251 |
| Rps4x | -3555 | -300 | -4680 | 5409 | -4453 |
| Rps5 | -4284 | 1344 | -1916 | 5993 | -4583 |
| Rps6 | -4272 | 4707 | 1599 | 6014 | -5295 |
| Rps7 | -5696 | 1849 | -3387 | 6808 | -5804 |
| Rps8 | -6704 | -566 | -5243 | 7004 | -6741 |
| Rps9 | -5004 | 1757 | -844 | 6794 | -4576 |
| Rpsa | -5034 | -2245 | -4844 | 5145 | -2970 |
| Sem1 | -6006 | 529 | -1985 | 6969 | -6676 |
| Slit1 | 3871 | -1008 | 4020 | -7294 | 120 |
| Slit2 | -4111 | 2740 | 7297 | -5917 | 3522 |
| Uba52 | -2504 | 5042 | 585 | 6605 | -5655 |
| Ubb | -4378 | 3667 | 1287 | 6541 | -5290 |
| Ubc | -1247 | 3415 | 2683 | -2012 | -1479 |
| Upf2 | -3464 | -2789 | -5456 | 1772 | -4025 |
| Upf3a | 6309 | 4755 | 7420 | 4843 | -6023 |
| Upf3b | -5155 | 749 | -5684 | 2733 | -7352 |
| Usp33 | -6044 | -3231 | -1192 | -7282 | 6858 |
| Zswim8 | 1963 | -2865 | 6580 | -8108 | 285 |
FORMATION OF ATP BY CHEMIOSMOTIC COUPLING
| metric | value |
|---|---|
| setSize | 18 |
| pMANOVA | 1.68e-07 |
| p.adjustMANOVA | 1.89e-06 |
| s.dist | 0.857 |
| s.hyp | -0.307 |
| s.hip | -0.0183 |
| s.amy | -0.129 |
| s.pag | 0.744 |
| s.ni | -0.265 |
| p.hyp | 0.0242 |
| p.hip | 0.893 |
| p.amy | 0.345 |
| p.pag | 4.54e-08 |
| p.ni | 0.0515 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | hyp |
|---|---|---|
| Atp5pb | 7041 | -6320 |
| Atp5h | 6974 | -6360 |
| Atp5l | 6883 | -5052 |
| Atp5g1 | 7378 | -4692 |
| Atp5j2 | 7316 | -4698 |
| Atp5o | 6868 | -4664 |
| Atp5c1 | 7028 | -4528 |
| Atp5j | 7355 | -3873 |
| Atp5e | 7347 | -3475 |
| Atp5k | 7555 | -1416 |
| mt-Atp8 | 7195 | -903 |
| Atp5g3 | 7058 | -864 |
| Atp5b | 6630 | -231 |
| mt-Atp6 | 106 | -5861 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Atp5a1 | 85 | 172 | 1149 | 1994 | 5105 |
| Atp5b | -231 | -1196 | -507 | 6630 | 4246 |
| Atp5c1 | -4528 | 1091 | -16 | 7028 | 3513 |
| Atp5d | 2242 | 2763 | 3781 | 6545 | 638 |
| Atp5e | -3475 | 1465 | 39 | 7347 | -5736 |
| Atp5g1 | -4692 | -4063 | -1542 | 7378 | -921 |
| Atp5g2 | 26 | -1871 | -3640 | -7013 | 752 |
| Atp5g3 | -864 | 42 | -460 | 7058 | -4178 |
| Atp5h | -6360 | 541 | 267 | 6974 | -4132 |
| Atp5j | -3873 | 1215 | 163 | 7355 | -6047 |
| Atp5j2 | -4698 | -1005 | 213 | 7316 | -5367 |
| Atp5k | -1416 | -6858 | 5172 | 7555 | -7273 |
| Atp5l | -5052 | -1318 | -3961 | 6883 | -3766 |
| Atp5o | -4664 | 4376 | 2037 | 6868 | 43 |
| Atp5pb | -6320 | 3248 | -2868 | 7041 | -1118 |
| Dmac2l | 3196 | -3702 | -4386 | 5033 | 7358 |
| mt-Atp6 | -5861 | -4290 | -7296 | 106 | -5176 |
| mt-Atp8 | -903 | -4537 | -6588 | 7195 | -7172 |
RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS
| metric | value |
|---|---|
| setSize | 125 |
| pMANOVA | 1.57e-49 |
| p.adjustMANOVA | 1.51e-47 |
| s.dist | 0.841 |
| s.hyp | -0.389 |
| s.hip | 0.0804 |
| s.amy | -0.0697 |
| s.pag | 0.687 |
| s.ni | -0.27 |
| p.hyp | 5.65e-14 |
| p.hip | 0.121 |
| p.amy | 0.179 |
| p.pag | 3.01e-40 |
| p.ni | 1.81e-07 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | hyp |
|---|---|---|
| Ndufaf2 | 7198 | -7557 |
| Ndufa6 | 7289 | -6844 |
| Ndufc1 | 7415 | -6020 |
| Atp5pb | 7041 | -6320 |
| Atp5h | 6974 | -6360 |
| Ndufb5 | 6768 | -6381 |
| Ndufv2 | 6958 | -6176 |
| Uqcr10 | 7414 | -5777 |
| Ndufaf5 | 5854 | -7301 |
| Ndufa4 | 7443 | -5550 |
| Tmem186 | 6454 | -6371 |
| Cox16 | 6517 | -6282 |
| Ndufaf6 | 6296 | -6441 |
| Uqcrh | 7167 | -5590 |
| Ndufs5 | 7341 | -5414 |
| Ndufb8 | 7254 | -5455 |
| Ndufb1 | 7534 | -5136 |
| mt-Nd3 | 5046 | -7666 |
| Ndufb7 | 7060 | -5348 |
| Ndufb2 | 6803 | -5495 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Acad9 | -5676 | 366 | -1294 | -1492 | 6692 |
| Atp5a1 | 85 | 172 | 1149 | 1994 | 5105 |
| Atp5b | -231 | -1196 | -507 | 6630 | 4246 |
| Atp5c1 | -4528 | 1091 | -16 | 7028 | 3513 |
| Atp5d | 2242 | 2763 | 3781 | 6545 | 638 |
| Atp5e | -3475 | 1465 | 39 | 7347 | -5736 |
| Atp5g1 | -4692 | -4063 | -1542 | 7378 | -921 |
| Atp5g2 | 26 | -1871 | -3640 | -7013 | 752 |
| Atp5g3 | -864 | 42 | -460 | 7058 | -4178 |
| Atp5h | -6360 | 541 | 267 | 6974 | -4132 |
| Atp5j | -3873 | 1215 | 163 | 7355 | -6047 |
| Atp5j2 | -4698 | -1005 | 213 | 7316 | -5367 |
| Atp5k | -1416 | -6858 | 5172 | 7555 | -7273 |
| Atp5l | -5052 | -1318 | -3961 | 6883 | -3766 |
| Atp5o | -4664 | 4376 | 2037 | 6868 | 43 |
| Atp5pb | -6320 | 3248 | -2868 | 7041 | -1118 |
| Coq10a | -872 | 174 | 5512 | 5642 | 391 |
| Coq10b | -6767 | -4385 | -6656 | -1657 | 4691 |
| Cox11 | -5932 | 7313 | 440 | 3726 | 8009 |
| Cox14 | 706 | 4447 | -776 | 7356 | -1516 |
| Cox16 | -6282 | 2257 | -655 | 6517 | -6680 |
| Cox18 | -3104 | -1376 | 5803 | 3205 | -3296 |
| Cox19 | -5148 | -5349 | 3732 | 5991 | 873 |
| Cox20 | -1044 | 4893 | -7512 | 6453 | -7393 |
| Cox4i1 | -3460 | -1188 | 515 | 7220 | -2439 |
| Cox5a | -4271 | 1133 | 261 | 7346 | -4824 |
| Cox5b | -2705 | 2950 | 1495 | 7376 | -6255 |
| Cox6a1 | -1788 | 328 | -119 | 7216 | -4900 |
| Cox6b1 | -3261 | -444 | 1867 | 7386 | -3016 |
| Cox6c | -4918 | -2459 | -1646 | 7401 | -6749 |
| Cox7a2l | -4693 | 1079 | -1681 | 6310 | -3384 |
| Cox7b | -4523 | 1796 | 982 | 7333 | -4507 |
| Cox7c | -4742 | -5409 | -360 | 7511 | -6259 |
| Cox8a | -2866 | -1850 | 3090 | 7510 | -4137 |
| Cyc1 | -2233 | 4850 | 3117 | 7172 | 3586 |
| Cycs | -4981 | -5765 | -4663 | 5515 | -1835 |
| Dmac2l | 3196 | -3702 | -4386 | 5033 | 7358 |
| Ecsit | -1051 | -2710 | -1024 | 3059 | 4374 |
| Etfa | -752 | 6447 | -2498 | 4988 | 3243 |
| Etfb | -1476 | 2943 | -3519 | 6573 | -4684 |
| Etfdh | -2121 | -2201 | 843 | 4969 | 4804 |
| Lrpprc | 4844 | 219 | 3885 | -1624 | 4485 |
| mt-Atp6 | -5861 | -4290 | -7296 | 106 | -5176 |
| mt-Atp8 | -903 | -4537 | -6588 | 7195 | -7172 |
| mt-Co1 | -6566 | -5691 | -7888 | -4846 | 3504 |
| mt-Co2 | -6934 | -6438 | -7852 | -408 | -6525 |
| mt-Co3 | -7004 | -7097 | -7148 | 3668 | -3117 |
| mt-Cytb | -6223 | -5636 | -7841 | -2825 | -4086 |
| mt-Nd1 | -6928 | -5185 | -7660 | -3622 | -4224 |
| mt-Nd2 | -7861 | -4570 | -7273 | -8198 | -1645 |
| mt-Nd3 | -7666 | -6680 | -4666 | 5046 | -7075 |
| mt-Nd4 | -7348 | -6449 | -7717 | -6517 | -1867 |
| mt-Nd5 | -7124 | -4082 | -7797 | -7940 | 4926 |
| mt-Nd6 | -8023 | 2876 | -4700 | 100 | -6865 |
| Ndufa1 | -1642 | -1771 | 25 | 7523 | -7305 |
| Ndufa10 | -1375 | 769 | 49 | 6233 | 457 |
| Ndufa11 | -4843 | 2880 | 3522 | 7197 | -608 |
| Ndufa12 | -1267 | 1783 | -1884 | 7022 | -5851 |
| Ndufa13 | -493 | -2327 | -476 | 7372 | -6180 |
| Ndufa2 | -4537 | -3358 | 2985 | 7507 | -6445 |
| Ndufa3 | -2637 | -3209 | 4823 | 7520 | -6859 |
| Ndufa4 | -5550 | 879 | 695 | 7443 | -6311 |
| Ndufa5 | -2620 | 2624 | -4109 | 7373 | -7195 |
| Ndufa6 | -6844 | 2822 | 1084 | 7289 | -7245 |
| Ndufa7 | -4884 | 3044 | 195 | 7181 | -719 |
| Ndufa8 | -3930 | 4826 | -2935 | 6143 | -2093 |
| Ndufa9 | -2068 | 488 | 2622 | 5779 | 4053 |
| Ndufab1 | -719 | -1773 | 1653 | 6967 | -4334 |
| Ndufaf1 | -5335 | 2520 | -173 | 4543 | -403 |
| Ndufaf2 | -7557 | -2229 | -89 | 7198 | -1969 |
| Ndufaf3 | 1992 | -3493 | 6320 | 6633 | -5590 |
| Ndufaf4 | -7221 | -8261 | -7354 | 3011 | -2079 |
| Ndufaf5 | -7301 | 6059 | -4640 | 5854 | 32 |
| Ndufaf6 | -6441 | -1241 | 977 | 6296 | -2306 |
| Ndufaf7 | -846 | -862 | 647 | 5389 | -1634 |
| Ndufb1 | -5136 | -4408 | 4888 | 7534 | -6898 |
| Ndufb10 | -2943 | -2704 | -955 | 6844 | -5638 |
| Ndufb11 | -5045 | 1491 | -1381 | 6729 | -6277 |
| Ndufb2 | -5495 | -3363 | -493 | 6803 | -4662 |
| Ndufb3 | -4901 | 1103 | 1115 | 7318 | -6494 |
| Ndufb4 | -4431 | 4159 | -2771 | 6606 | -1293 |
| Ndufb5 | -6381 | -2510 | 270 | 6768 | -3161 |
| Ndufb6 | -5142 | -5657 | 1899 | 6739 | -1364 |
| Ndufb7 | -5348 | 4587 | 1129 | 7060 | -5502 |
| Ndufb8 | -5455 | 591 | 1725 | 7254 | -333 |
| Ndufb9 | -5088 | -751 | 661 | 7322 | -4018 |
| Ndufc1 | -6020 | -136 | -2495 | 7415 | -6066 |
| Ndufc2 | -4295 | 417 | -4151 | 7276 | -4063 |
| Ndufs1 | 3181 | 5455 | 2072 | 1262 | 6289 |
| Ndufs2 | 449 | 1114 | 1294 | 6867 | -257 |
| Ndufs3 | -1117 | -2046 | 2011 | 6166 | -1401 |
| Ndufs4 | -4999 | 3455 | -2569 | 7305 | -2336 |
| Ndufs5 | -5414 | 852 | 1064 | 7341 | -6250 |
| Ndufs6 | -3788 | -280 | 2472 | 7369 | -6459 |
| Ndufs7 | -1023 | 4628 | -348 | 5983 | 355 |
| Ndufs8 | -2992 | 3128 | -1185 | 6711 | -1521 |
| Ndufv1 | -847 | -2170 | 5300 | 6852 | 121 |
| Ndufv2 | -6176 | 1293 | -2541 | 6958 | -2516 |
| Ndufv3 | -2781 | 4189 | 58 | 6995 | -6906 |
| Nubpl | -5005 | -3952 | -2336 | 6663 | 2142 |
| Pm20d1 | -460 | 195 | -6635 | -7154 | 6408 |
| Sco1 | 6003 | 3379 | -1586 | -23 | -4234 |
| Sco2 | -4440 | 7309 | -4790 | 2005 | 3240 |
| Sdha | 1625 | 412 | -402 | -307 | 2983 |
| Sdhb | -3060 | 1036 | 4033 | 6049 | 2667 |
| Sdhc | -3701 | 1262 | -4103 | 4609 | 2812 |
| Sdhd | -1537 | -1697 | 3628 | 7189 | 6034 |
| Slc25a14 | -4554 | 1014 | 1518 | 4345 | -2419 |
| Slc25a27 | 2994 | -4140 | -508 | -4968 | -6824 |
| Surf1 | -295 | 6094 | -2113 | 6860 | 2659 |
| Taco1 | -2002 | 843 | 2808 | -4123 | 7664 |
| Timmdc1 | -4766 | -2177 | 3005 | 6897 | 95 |
| Tmem126b | -5439 | 2670 | -3406 | 6075 | -4984 |
| Tmem186 | -6371 | 6143 | 5973 | 6454 | -2551 |
| Trap1 | 3061 | 3914 | 4469 | 4129 | 8176 |
| Ucp2 | 7565 | 7355 | 6397 | 7529 | 7955 |
| Ucp3 | 7787 | 6629 | -3444 | 6988 | 8403 |
| Uqcr10 | -5777 | 2680 | 4091 | 7414 | -4487 |
| Uqcr11 | -2063 | -1401 | 976 | 7430 | -5850 |
| Uqcrb | -3491 | -4744 | 1751 | 7153 | -5743 |
| Uqcrc1 | -3385 | 3074 | 2069 | 7101 | 2064 |
| Uqcrc2 | -3878 | 2883 | -1300 | 5852 | 5995 |
| Uqcrfs1 | -1882 | 3351 | 1810 | 6908 | 2495 |
| Uqcrh | -5590 | 1885 | -1120 | 7167 | -1739 |
| Uqcrq | -4697 | -513 | -713 | 7472 | -5260 |
SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS
| metric | value |
|---|---|
| setSize | 11 |
| pMANOVA | 0.00116 |
| p.adjustMANOVA | 0.00495 |
| s.dist | 0.826 |
| s.hyp | -0.442 |
| s.hip | 0.165 |
| s.amy | 0.199 |
| s.pag | 0.537 |
| s.ni | -0.364 |
| p.hyp | 0.0112 |
| p.hip | 0.342 |
| p.amy | 0.254 |
| p.pag | 0.00205 |
| p.ni | 0.0368 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | hyp |
|---|---|---|
| Snrpf | 6924 | -6604 |
| Snrpd3 | 6759 | -6090 |
| Snrpe | 7364 | -5188 |
| Slbp | 3956 | -5763 |
| Snrpb | 5392 | -3753 |
| Snrpg | 7388 | -1736 |
| Ncbp2 | 5157 | -2016 |
| Lsm10 | 2625 | -2737 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Lsm10 | -2737 | -1568 | -945 | 2625 | -5055 |
| Lsm11 | -5856 | -4711 | -456 | -4122 | 6156 |
| Ncbp1 | 472 | -1721 | 5922 | 1206 | 2493 |
| Ncbp2 | -2016 | 5799 | 659 | 5157 | -5666 |
| Slbp | -5763 | 1364 | -4150 | 3956 | 2727 |
| Snrpb | -3753 | 314 | 2874 | 5392 | 3672 |
| Snrpd3 | -6090 | 4113 | 4393 | 6759 | -6403 |
| Snrpe | -5188 | 5342 | -793 | 7364 | -7018 |
| Snrpf | -6604 | 2566 | 4624 | 6924 | -7296 |
| Snrpg | -1736 | -3264 | 3990 | 7388 | -6388 |
| Zfp473 | -1563 | -599 | 1377 | -177 | -3755 |
REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO
| metric | value |
|---|---|
| setSize | 10 |
| pMANOVA | 0.00107 |
| p.adjustMANOVA | 0.00464 |
| s.dist | 0.818 |
| s.hyp | 0.233 |
| s.hip | -0.103 |
| s.amy | 0.567 |
| s.pag | -0.49 |
| s.ni | 0.208 |
| p.hyp | 0.202 |
| p.hip | 0.572 |
| p.amy | 0.00191 |
| p.pag | 0.00729 |
| p.ni | 0.256 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | amy | pag |
|---|---|---|
| Slit2 | 7297 | -5917 |
| Robo2 | 6428 | -4801 |
| Nell2 | 7862 | -3820 |
| Slit1 | 4020 | -7294 |
| Robo3 | 4337 | -6539 |
| Src | 4443 | -3308 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Dcc | 2883 | -1945 | -439 | -4529 | -3180 |
| Nell2 | 2237 | -2354 | 7862 | -3820 | 1923 |
| Ntn1 | -2865 | 4380 | 4528 | 310 | 246 |
| Robo1 | -2715 | -456 | -179 | -7831 | 6091 |
| Robo2 | 6889 | -5001 | 6428 | -4801 | 7272 |
| Robo3 | 6257 | -7159 | 4337 | -6539 | -164 |
| Slit1 | 3871 | -1008 | 4020 | -7294 | 120 |
| Slit2 | -4111 | 2740 | 7297 | -5917 | 3522 |
| Slit3 | 2750 | -1245 | 6994 | 337 | 4722 |
| Src | 1566 | -2471 | 4443 | -3308 | 949 |
FORMATION OF FIBRIN CLOT CLOTTING CASCADE
| metric | value |
|---|---|
| setSize | 18 |
| pMANOVA | 8.81e-07 |
| p.adjustMANOVA | 8.38e-06 |
| s.dist | 0.811 |
| s.hyp | 0.169 |
| s.hip | 0.631 |
| s.amy | -0.293 |
| s.pag | 0.297 |
| s.ni | 0.239 |
| p.hyp | 0.214 |
| p.hip | 3.56e-06 |
| p.amy | 0.0312 |
| p.pag | 0.0291 |
| p.ni | 0.0793 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | hip | pag |
|---|---|---|
| F3 | 7347 | 7540 |
| C1qbp | 6114 | 6818 |
| A2m | 7332 | 4005 |
| Serping1 | 7036 | 3323 |
| Prtn3 | 4107 | 4779 |
| Serpind1 | 3258 | 4959 |
| F2r | 7343 | 1908 |
| Tfpi | 5643 | 2305 |
| Thbd | 3380 | 3778 |
| Gp5 | 6378 | 1645 |
| Serpine2 | 4514 | 1992 |
| Pros1 | 6697 | 1068 |
| F13a1 | 1662 | 3998 |
| Serpinc1 | 2102 | 295 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| A2m | 7498 | 7332 | -134 | 4005 | 7093 |
| C1qbp | -3397 | 6114 | -1786 | 6818 | -2779 |
| F13a1 | 3798 | 1662 | -3575 | 3998 | 1155 |
| F2r | -7968 | 7343 | -5298 | 1908 | 3947 |
| F3 | 5900 | 7347 | 3843 | 7540 | 8225 |
| F8 | 1136 | 6657 | -5904 | -4104 | 3109 |
| Gp1ba | -5216 | 2836 | 7902 | -1184 | -6285 |
| Gp5 | 512 | 6378 | -3029 | 1645 | 7244 |
| Prcp | 1683 | -8538 | -5058 | 15 | 3328 |
| Pros1 | 7448 | 6697 | -6566 | 1068 | 4927 |
| Prtn3 | 7056 | 4107 | -1808 | 4779 | 2459 |
| Serpinc1 | -7866 | 2102 | -3199 | 295 | 399 |
| Serpind1 | -531 | 3258 | -5931 | 4959 | -2730 |
| Serpine2 | -6505 | 4514 | -7197 | 1992 | 2502 |
| Serping1 | 6485 | 7036 | -3977 | 3323 | 4054 |
| Tfpi | 5240 | 5643 | 4935 | 2305 | -1591 |
| Thbd | 6199 | 3380 | 923 | 3778 | 6939 |
| Vwf | -443 | 5512 | -6247 | -8107 | 1199 |
SIGNALING BY HIPPO
| metric | value |
|---|---|
| setSize | 20 |
| pMANOVA | 7.87e-07 |
| p.adjustMANOVA | 7.75e-06 |
| s.dist | 0.806 |
| s.hyp | -0.401 |
| s.hip | -0.0681 |
| s.amy | -0.418 |
| s.pag | -0.543 |
| s.ni | 0.12 |
| p.hyp | 0.0019 |
| p.hip | 0.598 |
| p.amy | 0.0012 |
| p.pag | 2.62e-05 |
| p.ni | 0.351 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | amy |
|---|---|---|
| Amotl1 | -8365 | -6810 |
| Tjp1 | -7565 | -6804 |
| Amotl2 | -6699 | -7126 |
| Tjp2 | -6064 | -7580 |
| Wwtr1 | -8101 | -5538 |
| Mob1a | -6528 | -6360 |
| Stk4 | -7287 | -5361 |
| Sav1 | -5365 | -6935 |
| Lats1 | -6521 | -5335 |
| Mob1b | -5983 | -5177 |
| Lats2 | -3760 | -4410 |
| Amot | -3116 | -3776 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Amot | -6433 | -859 | -3776 | -3116 | 7624 |
| Amotl1 | -5853 | 2512 | -6810 | -8365 | -3295 |
| Amotl2 | -8138 | -5509 | -7126 | -6699 | 4014 |
| Casp3 | -7115 | 6951 | -6261 | 928 | 3348 |
| Dvl2 | 2016 | -5381 | 6196 | -6308 | -166 |
| Lats1 | 80 | 1772 | -5335 | -6521 | 6386 |
| Lats2 | 2611 | 1907 | -4410 | -3760 | 7696 |
| Mob1a | 5394 | 642 | -6360 | -6528 | 2753 |
| Mob1b | 549 | -783 | -5177 | -5983 | 1607 |
| Nphp4 | 7608 | 798 | 7898 | -6590 | 4611 |
| Sav1 | -3347 | 3437 | -6935 | -5365 | -4599 |
| Stk3 | -6397 | 316 | -6437 | 3080 | 5683 |
| Stk4 | -3164 | -5734 | -5361 | -7287 | -1814 |
| Tjp1 | -5127 | -7568 | -6804 | -7565 | 2138 |
| Tjp2 | -7727 | -5398 | -7580 | -6064 | -1128 |
| Wwc1 | -7838 | -8161 | 1453 | -8191 | -5332 |
| Wwtr1 | -7972 | -4885 | -5538 | -8101 | -3716 |
| Yap1 | -7159 | -1987 | 1051 | -6878 | -1741 |
| Ywhab | -5536 | 2615 | 1474 | 3514 | 5870 |
| Ywhae | -4153 | 1888 | -914 | 603 | -860 |
RHOBTB2 GTPASE CYCLE
| metric | value |
|---|---|
| setSize | 23 |
| pMANOVA | 3.79e-05 |
| p.adjustMANOVA | 0.000244 |
| s.dist | 0.796 |
| s.hyp | -0.422 |
| s.hip | -0.385 |
| s.amy | -0.236 |
| s.pag | -0.238 |
| s.ni | -0.442 |
| p.hyp | 0.000466 |
| p.hip | 0.00139 |
| p.amy | 0.0498 |
| p.pag | 0.0484 |
| p.ni | 0.000245 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | ni | hyp |
|---|---|---|
| Hsp90ab1 | -6462 | -7658 |
| Hsp90aa1 | -6162 | -7973 |
| Cct7 | -5938 | -7381 |
| Phip | -5523 | -6508 |
| Rhobtb2 | -5900 | -5283 |
| Cct6a | -3098 | -7949 |
| Cct2 | -2928 | -6976 |
| Hnrnpc | -3095 | -5645 |
| Actn1 | -4047 | -4097 |
| Cdc37 | -4820 | -2511 |
| Actg1 | -2859 | -2521 |
| Ddx39b | -5153 | -1086 |
| Tra2b | -492 | -7711 |
| Cul3 | -655 | -4616 |
| Twf1 | -1296 | -1485 |
| Stk38 | -4956 | -287 |
| Tmod3 | -246 | -4900 |
| Msi2 | -106 | -758 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Actg1 | -2521 | -3285 | 4182 | 1997 | -2859 |
| Actn1 | -4097 | -7609 | 5452 | -8249 | -4047 |
| Cct2 | -6976 | -6216 | -4431 | 2670 | -2928 |
| Cct6a | -7949 | -4985 | -4197 | -717 | -3098 |
| Cct7 | -7381 | -8123 | -2899 | 2117 | -5938 |
| Cdc37 | -2511 | 3489 | 3276 | 5313 | -4820 |
| Cul3 | -4616 | 3239 | -5743 | -5327 | -655 |
| Dbn1 | 2269 | -5035 | 7132 | -2838 | -2637 |
| Ddx39b | -1086 | -3497 | 7087 | -532 | -5153 |
| Hnrnpc | -5645 | -3175 | -3758 | 3345 | -3095 |
| Hsp90aa1 | -7973 | -8277 | -7326 | -4822 | -6162 |
| Hsp90ab1 | -7658 | -7115 | -4184 | -3700 | -6462 |
| Msi2 | -758 | 2558 | -5875 | -4796 | -106 |
| Myo6 | 1005 | -4877 | -6881 | -4886 | 3954 |
| Phip | -6508 | -8397 | -6152 | -7991 | -5523 |
| Rbmx | 6518 | 175 | 6256 | -1963 | -6001 |
| Rhobtb2 | -5283 | -8473 | -667 | -5498 | -5900 |
| Srrm1 | 1839 | -924 | 2000 | -7322 | -2672 |
| Stk38 | -287 | -7128 | -5626 | -3111 | -4956 |
| Tmod3 | -4900 | -5727 | -5963 | -4093 | -246 |
| Tra2b | -7711 | -6188 | -5181 | -722 | -492 |
| Twf1 | -1485 | 3077 | -6347 | -4481 | -1296 |
| Txnl1 | -7879 | 1400 | -3468 | 2165 | 1326 |
CAMK IV MEDIATED PHOSPHORYLATION OF CREB
| metric | value |
|---|---|
| setSize | 10 |
| pMANOVA | 0.00828 |
| p.adjustMANOVA | 0.0251 |
| s.dist | 0.781 |
| s.hyp | 0.349 |
| s.hip | -0.255 |
| s.amy | 0.496 |
| s.pag | -0.14 |
| s.ni | 0.398 |
| p.hyp | 0.0563 |
| p.hip | 0.163 |
| p.amy | 0.00662 |
| p.pag | 0.444 |
| p.ni | 0.0295 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | amy | ni |
|---|---|---|
| Camkk1 | 7760 | 7583 |
| Camkk2 | 7829 | 5886 |
| Camk4 | 4549 | 7655 |
| Camk2g | 2753 | 7086 |
| Camk2a | 6629 | 2594 |
| Camk2d | 4117 | 3253 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Calm1 | -3210 | -5777 | -2383 | 480 | 4856 |
| Camk2a | 7207 | -4146 | 6629 | -5758 | 2594 |
| Camk2b | 7405 | -663 | 7585 | 1811 | -336 |
| Camk2d | 3624 | 5724 | 4117 | -6480 | 3253 |
| Camk2g | -2481 | -772 | 2753 | 2961 | 7086 |
| Camk4 | 6681 | -5705 | 4549 | -2352 | 7655 |
| Camkk1 | 7495 | 669 | 7760 | 687 | 7583 |
| Camkk2 | 7234 | -7198 | 7829 | -2116 | 5886 |
| Creb1 | -6520 | -8363 | -6284 | -8066 | 984 |
| Kpna2 | -1424 | -416 | 7080 | 3403 | -2875 |
CRISTAE FORMATION
| metric | value |
|---|---|
| setSize | 31 |
| pMANOVA | 1.6e-10 |
| p.adjustMANOVA | 2.79e-09 |
| s.dist | 0.781 |
| s.hyp | -0.275 |
| s.hip | 0.052 |
| s.amy | -0.0763 |
| s.pag | 0.69 |
| s.ni | -0.222 |
| p.hyp | 0.00811 |
| p.hip | 0.617 |
| p.amy | 0.462 |
| p.pag | 2.84e-11 |
| p.ni | 0.0323 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | hyp |
|---|---|---|
| Micos13 | 7227 | -6812 |
| Atp5pb | 7041 | -6320 |
| Atp5h | 6974 | -6360 |
| Chchd6 | 6724 | -5426 |
| Atp5l | 6883 | -5052 |
| Atp5g1 | 7378 | -4692 |
| Atp5j2 | 7316 | -4698 |
| Tmem11 | 6817 | -5012 |
| Atp5o | 6868 | -4664 |
| Atp5c1 | 7028 | -4528 |
| Micos10 | 6275 | -4831 |
| Atp5j | 7355 | -3873 |
| Atp5e | 7347 | -3475 |
| Apoo | 7345 | -2439 |
| Chchd3 | 7175 | -2013 |
| Atp5k | 7555 | -1416 |
| Apool | 3540 | -2029 |
| mt-Atp8 | 7195 | -903 |
| Atp5g3 | 7058 | -864 |
| Immt | 2423 | -2338 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Apoo | -2439 | 5138 | -1870 | 7345 | 1517 |
| Apool | -2029 | -799 | 498 | 3540 | -2403 |
| Atp5a1 | 85 | 172 | 1149 | 1994 | 5105 |
| Atp5b | -231 | -1196 | -507 | 6630 | 4246 |
| Atp5c1 | -4528 | 1091 | -16 | 7028 | 3513 |
| Atp5d | 2242 | 2763 | 3781 | 6545 | 638 |
| Atp5e | -3475 | 1465 | 39 | 7347 | -5736 |
| Atp5g1 | -4692 | -4063 | -1542 | 7378 | -921 |
| Atp5g2 | 26 | -1871 | -3640 | -7013 | 752 |
| Atp5g3 | -864 | 42 | -460 | 7058 | -4178 |
| Atp5h | -6360 | 541 | 267 | 6974 | -4132 |
| Atp5j | -3873 | 1215 | 163 | 7355 | -6047 |
| Atp5j2 | -4698 | -1005 | 213 | 7316 | -5367 |
| Atp5k | -1416 | -6858 | 5172 | 7555 | -7273 |
| Atp5l | -5052 | -1318 | -3961 | 6883 | -3766 |
| Atp5o | -4664 | 4376 | 2037 | 6868 | 43 |
| Atp5pb | -6320 | 3248 | -2868 | 7041 | -1118 |
| Chchd3 | -2013 | -2411 | 1394 | 7175 | -2172 |
| Chchd6 | -5426 | 3359 | 716 | 6724 | -690 |
| Dmac2l | 3196 | -3702 | -4386 | 5033 | 7358 |
| Dnajc11 | 4680 | -1605 | 3615 | 397 | 2249 |
| Hspa9 | -1762 | 1791 | -3119 | -402 | 2721 |
| Immt | -2338 | 874 | -2881 | 2423 | 6108 |
| Micos10 | -4831 | 664 | -1419 | 6275 | -4875 |
| Micos13 | -6812 | 3871 | -2735 | 7227 | -5800 |
| mt-Atp6 | -5861 | -4290 | -7296 | 106 | -5176 |
| mt-Atp8 | -903 | -4537 | -6588 | 7195 | -7172 |
| Mtx1 | 2550 | 1923 | 6338 | 6889 | -1599 |
| Mtx2 | -179 | -787 | 2691 | 5561 | -181 |
| Samm50 | -638 | -7884 | 1078 | -1768 | -1324 |
| Tmem11 | -5012 | 3191 | -4657 | 6817 | -3983 |
TRANSLATION
| metric | value |
|---|---|
| setSize | 286 |
| pMANOVA | 8.05e-94 |
| p.adjustMANOVA | 9.27e-91 |
| s.dist | 0.78 |
| s.hyp | -0.335 |
| s.hip | 0.141 |
| s.amy | -0.0779 |
| s.pag | 0.618 |
| s.ni | -0.298 |
| p.hyp | 1.99e-22 |
| p.hip | 4.36e-05 |
| p.amy | 0.0238 |
| p.pag | 1.27e-72 |
| p.ni | 4.67e-18 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | hyp |
|---|---|---|
| Mrps18c | 7176 | -7065 |
| Mrps28 | 7418 | -6811 |
| Rpl11 | 7106 | -7040 |
| Mrpl14 | 6661 | -7286 |
| Mrpl53 | 7284 | -6639 |
| Rpl31 | 7055 | -6836 |
| Rps23 | 6890 | -6959 |
| Rpl27 | 6972 | -6845 |
| Mrpl20 | 7258 | -6519 |
| Rps8 | 7004 | -6704 |
| Rpl26 | 7025 | -6659 |
| Rpl39 | 7435 | -6226 |
| Rps12 | 7047 | -6536 |
| Mrps7 | 6239 | -7344 |
| Rpl24 | 6934 | -6576 |
| Sec11c | 7039 | -6474 |
| Mrpl46 | 6237 | -7085 |
| Sec11a | 6199 | -7127 |
| Mrpl52 | 7390 | -5954 |
| Rpl19 | 7139 | -6145 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Aars | 3200 | -1243 | 4761 | -5430 | 3912 |
| Aars2 | -4687 | -565 | 4335 | -883 | 5522 |
| Aimp1 | -2821 | 5719 | 3587 | 6197 | -3383 |
| Aimp2 | -6494 | 1723 | 1316 | 5025 | -1429 |
| Apeh | 4336 | 2118 | 2648 | 3027 | 1721 |
| Aurkaip1 | -3086 | 3022 | 42 | 6936 | -4705 |
| Cars | 104 | -3364 | 5878 | 2833 | -3220 |
| Cars2 | -3833 | -5887 | -3336 | -16 | -4348 |
| Chchd1 | -4961 | 1272 | -3652 | 4586 | -4442 |
| Dap3 | -1253 | -4822 | 1211 | 3216 | -3270 |
| Dars | -7892 | 5922 | -3590 | 920 | 4739 |
| Dars2 | 3965 | 4103 | 6574 | -804 | 7994 |
| Ddost | -3345 | -3221 | 2102 | 2616 | -4771 |
| Ears2 | -7724 | -8152 | -6952 | -7156 | -5039 |
| Eef1a1 | -4411 | 2294 | -379 | 5219 | -1585 |
| Eef1a2 | -2588 | 1169 | 4877 | 143 | 6668 |
| Eef1b2 | -4710 | 2420 | 473 | 6170 | -4981 |
| Eef1d | -3728 | 5506 | -4520 | 6179 | -1242 |
| Eef1e1 | -4089 | 2160 | -2652 | 3568 | -2112 |
| Eef1g | -4818 | -581 | -3602 | 5481 | -4562 |
| Eef2 | 3372 | 350 | -1855 | 1302 | 5577 |
| Eif1ax | -5050 | 563 | -1955 | -625 | 7369 |
| Eif2b1 | 2982 | 1450 | -901 | 6024 | 5116 |
| Eif2b2 | -5516 | -4454 | 2377 | 5658 | 8178 |
| Eif2b3 | 2215 | 2475 | 828 | -950 | -3759 |
| Eif2b4 | 7283 | 38 | 2725 | 4551 | 2240 |
| Eif2b5 | 1288 | -5596 | 2078 | 3337 | 6169 |
| Eif2s1 | -6701 | -39 | -1217 | 5813 | 2921 |
| Eif2s2 | -4538 | -2403 | -5282 | 4050 | -5700 |
| Eif2s3x | 17 | -3878 | -3881 | -646 | 1396 |
| Eif3a | -6953 | -3944 | 1407 | -5013 | -7267 |
| Eif3b | 1168 | -6669 | 317 | 185 | 1132 |
| Eif3c | 5026 | 1285 | 6212 | 1990 | -609 |
| Eif3d | -246 | 5830 | 31 | 5012 | 3393 |
| Eif3e | -3996 | -271 | -1571 | 3711 | -2173 |
| Eif3f | -1429 | -114 | 5534 | 4747 | 1677 |
| Eif3g | -6158 | 4506 | -1026 | 6812 | -3309 |
| Eif3h | -5774 | 4130 | -1152 | 6092 | 398 |
| Eif3i | -5204 | 989 | 3667 | 6588 | 1783 |
| Eif3j1 | -933 | -3758 | -6113 | 5970 | -3553 |
| Eif3j2 | -7756 | -7169 | -7559 | -7227 | -640 |
| Eif3k | -5937 | 2750 | -2777 | 5339 | -2714 |
| Eif3l | 1203 | 1231 | 2859 | 4204 | 1293 |
| Eif3m | -3122 | 5534 | -872 | 6520 | 2334 |
| Eif4a1 | -5925 | -6104 | 4369 | 5645 | -6174 |
| Eif4a2 | -6255 | 2282 | -1778 | 4032 | 6477 |
| Eif4b | 7049 | 1455 | 4759 | -676 | 3264 |
| Eif4e | -2868 | 336 | -2621 | 4261 | 2119 |
| Eif4ebp1 | -884 | 6714 | 2834 | 3590 | -216 |
| Eif4g1 | 3439 | 953 | 4989 | -4135 | 2939 |
| Eif4h | 3731 | 704 | 3643 | 3900 | 5149 |
| Eif5 | 1858 | 2090 | 1643 | 4507 | 7317 |
| Eif5b | -1320 | -3993 | -2163 | 2055 | -7070 |
| Eprs | 7535 | -3999 | 5735 | 731 | -722 |
| Eral1 | -4952 | 934 | 643 | 4929 | 3792 |
| Etf1 | -4514 | -1719 | -5831 | 2237 | 745 |
| Fars2 | -1891 | 66 | 2600 | 4980 | 1813 |
| Farsa | 5058 | -2253 | 396 | 3116 | 3726 |
| Farsb | -4071 | 1254 | -3756 | 447 | 6473 |
| Fau | -5907 | 1583 | 1608 | 7212 | -5383 |
| Gadd45gip1 | -5657 | 6927 | -2559 | 7248 | -6665 |
| Gars | -1783 | -3875 | 2936 | 533 | 2555 |
| Gfm1 | -2018 | -937 | 1527 | 1626 | 6987 |
| Gfm2 | 1062 | -7473 | -3525 | -6490 | -3291 |
| Gspt1 | 1609 | -582 | -4047 | -5342 | 6563 |
| Gspt2 | -5177 | 6055 | 689 | -4954 | -1529 |
| Hars | -4231 | -4776 | -1446 | -151 | 4778 |
| Hars2 | -4336 | -7754 | 6189 | 1841 | 1391 |
| Iars | 3479 | -5780 | -3489 | -6464 | 6023 |
| Iars2 | -1282 | 4470 | 1856 | 130 | -57 |
| Kars | -3919 | -5643 | -4095 | 4476 | 3554 |
| Lars | 7141 | 5295 | 6692 | 2736 | 1842 |
| Lars2 | 3961 | 3386 | -7671 | 2923 | -2072 |
| Mars1 | 1094 | -4538 | 4234 | 181 | -4294 |
| Mars2 | -1357 | -1637 | -3125 | -5587 | -805 |
| Mrpl1 | 992 | 5947 | -2443 | 6649 | 5258 |
| Mrpl10 | 1879 | 1361 | -2761 | 4599 | -1740 |
| Mrpl11 | -5254 | 5334 | 1665 | 6839 | -3134 |
| Mrpl12 | -5882 | 4072 | -2217 | 6609 | -276 |
| Mrpl13 | -6207 | 2695 | -1459 | 6553 | -5019 |
| Mrpl14 | -7286 | -119 | 1512 | 6661 | -4211 |
| Mrpl15 | -2305 | 1549 | 863 | 6178 | 4693 |
| Mrpl16 | -1284 | 5083 | 2305 | 5753 | -2518 |
| Mrpl17 | -1714 | 3409 | 3223 | 5890 | 1456 |
| Mrpl18 | -5890 | -1549 | -1994 | 5860 | -3037 |
| Mrpl19 | 596 | -6654 | -4785 | 4294 | 663 |
| Mrpl2 | 1870 | 1052 | 3513 | 7315 | -2532 |
| Mrpl20 | -6519 | 2377 | 2323 | 7258 | -3749 |
| Mrpl21 | -2110 | 5249 | -981 | 6671 | -4232 |
| Mrpl22 | -2060 | 2064 | -5366 | 5105 | -5899 |
| Mrpl23 | 4859 | 6608 | 7517 | 6345 | 5644 |
| Mrpl24 | -3031 | -2024 | -898 | 3526 | -4571 |
| Mrpl27 | -4208 | 5727 | 2391 | 6774 | -4936 |
| Mrpl28 | -5222 | -318 | 115 | 6773 | -3335 |
| Mrpl3 | 1174 | 5406 | 2209 | 4493 | 5245 |
| Mrpl30 | -4723 | -7449 | -4961 | 7085 | -4843 |
| Mrpl32 | -744 | 1078 | -2106 | 5355 | -5809 |
| Mrpl33 | -6497 | 1202 | -4073 | 6503 | -5647 |
| Mrpl34 | -4227 | 4066 | 1161 | 6463 | 664 |
| Mrpl35 | -4084 | -7926 | -2449 | 6136 | -3332 |
| Mrpl36 | 1669 | -4014 | -3043 | 5490 | 899 |
| Mrpl37 | -4200 | -2415 | 6182 | 3310 | -2662 |
| Mrpl38 | -5630 | -1707 | -140 | 5052 | 5520 |
| Mrpl39 | -2052 | -2049 | -2448 | 6571 | 4690 |
| Mrpl4 | 2848 | -3719 | 587 | 4090 | 4241 |
| Mrpl40 | -1688 | -635 | 2112 | 6926 | -149 |
| Mrpl41 | -1196 | 4119 | -114 | 7186 | -2810 |
| Mrpl42 | -4711 | 1149 | -1566 | 6210 | -5136 |
| Mrpl43 | 2128 | 6123 | 3105 | 6914 | -1411 |
| Mrpl44 | -330 | 1775 | -2714 | 6957 | -236 |
| Mrpl46 | -7085 | 4523 | 2912 | 6237 | 715 |
| Mrpl47 | -5944 | 2207 | -1391 | 4451 | -6722 |
| Mrpl48 | -6124 | -2533 | -1624 | 6942 | -1540 |
| Mrpl49 | -2365 | 5073 | -1722 | 6491 | 4270 |
| Mrpl50 | -1198 | 1058 | -5051 | 4751 | -72 |
| Mrpl51 | -4570 | 404 | -5422 | 7040 | -4837 |
| Mrpl52 | -5954 | 1977 | -1130 | 7390 | -7235 |
| Mrpl53 | -6639 | 1342 | 2774 | 7284 | 1770 |
| Mrpl54 | -2430 | 6666 | 1091 | 7299 | -113 |
| Mrpl55 | -1268 | 4941 | 3529 | 6330 | -3406 |
| Mrpl57 | -6419 | 3753 | 294 | 6037 | -1433 |
| Mrpl58 | -644 | 7271 | -505 | 7526 | -1114 |
| Mrpl9 | 4967 | -648 | 5546 | 6962 | 8185 |
| Mrps10 | -1298 | 2599 | 1556 | 6347 | -6188 |
| Mrps11 | -3356 | 4316 | -4616 | 4464 | -2541 |
| Mrps12 | -4618 | -969 | -2510 | 7009 | -1687 |
| Mrps14 | -4998 | 3422 | -1075 | 6290 | -4505 |
| Mrps15 | 3255 | 4779 | 5761 | 6181 | -7028 |
| Mrps16 | -3689 | -728 | 3672 | 7136 | -2981 |
| Mrps17 | -3198 | -4205 | 721 | 6176 | -2111 |
| Mrps18a | -5153 | 773 | 375 | 5147 | -4985 |
| Mrps18b | 1882 | 4699 | 6568 | 5615 | 3311 |
| Mrps18c | -7065 | 5718 | 1280 | 7176 | -4449 |
| Mrps2 | -5187 | 3643 | -3063 | 3194 | -1712 |
| Mrps21 | -1319 | -1469 | -1393 | 7411 | -6422 |
| Mrps22 | -7948 | 2226 | -3386 | 5476 | 27 |
| Mrps23 | -1105 | 2061 | 446 | 6563 | 1203 |
| Mrps24 | -3065 | 4540 | -715 | 6986 | -5226 |
| Mrps25 | -2151 | -2197 | 1641 | 4566 | -4358 |
| Mrps26 | -2660 | 6707 | 1526 | 7237 | -2044 |
| Mrps27 | -2279 | 2536 | 5187 | 6772 | 2400 |
| Mrps28 | -6811 | 5250 | -284 | 7418 | 4481 |
| Mrps30 | -1493 | -76 | -340 | 2793 | 7545 |
| Mrps31 | -2956 | 5290 | -6391 | 1471 | -6530 |
| Mrps33 | -3032 | 2817 | 2967 | 7164 | -5463 |
| Mrps34 | -1524 | 5391 | 4883 | 7215 | -2980 |
| Mrps35 | -4109 | -2386 | -4247 | 5154 | -5105 |
| Mrps36 | -528 | 1971 | -5580 | 6482 | -2136 |
| Mrps5 | -3252 | 4678 | -5618 | 1452 | -3187 |
| Mrps6 | -6365 | -347 | -3933 | 5125 | -5302 |
| Mrps7 | -7344 | 2502 | -1725 | 6239 | -3589 |
| Mrps9 | -2595 | 4672 | -159 | 6221 | -6523 |
| Mrrf | -7772 | 1183 | -3588 | 5073 | 2464 |
| Mtfmt | 1689 | -5402 | 6027 | 5724 | -7073 |
| Mtif2 | 4688 | 4640 | -1816 | 4425 | -3488 |
| Mtif3 | -1214 | -341 | 2008 | 4991 | -1724 |
| Mtrf1l | -1708 | -2289 | -7824 | -4404 | -4230 |
| N6amt1 | -2858 | 7114 | 5278 | 7000 | -1276 |
| Nars | -4966 | -971 | -6979 | 2552 | 5196 |
| Nars2 | 4863 | 606 | -441 | 1143 | 1622 |
| Oxa1l | 2952 | 3978 | 5784 | 2108 | 7131 |
| Pabpc1 | -4196 | -1362 | 4329 | -2356 | -620 |
| Pars2 | 36 | 5386 | 4577 | -5659 | -4308 |
| Ppa1 | -6926 | 1357 | -4181 | 4045 | -2994 |
| Ppa2 | -2490 | 5091 | -382 | 6994 | -2196 |
| Ptcd3 | -2581 | -4130 | -1696 | 1339 | 1168 |
| Qars | -1177 | -2125 | 1998 | -1044 | 5216 |
| Rars | -1491 | -2819 | -3228 | 5096 | 3454 |
| Rars2 | 4918 | 5836 | -3068 | 5662 | -3739 |
| Rpl10 | 7552 | 2305 | -6483 | 1980 | 1798 |
| Rpl10a | -4754 | 5887 | -3904 | 6315 | -6264 |
| Rpl11 | -7040 | -1610 | -1752 | 7106 | -5100 |
| Rpl12 | -1293 | 111 | -1276 | 5593 | -4815 |
| Rpl13 | -5435 | 705 | -309 | 7111 | -4751 |
| Rpl13a | -6127 | -800 | -4926 | 6137 | -3678 |
| Rpl14 | -4973 | 3377 | -3827 | 6231 | -6184 |
| Rpl15 | -1081 | 4664 | -97 | 5670 | -5225 |
| Rpl17 | -6154 | 1812 | -4356 | 5972 | -3587 |
| Rpl18 | -3623 | 1407 | 1250 | 6814 | -5632 |
| Rpl18a | -1090 | 3984 | -5189 | 6777 | -4423 |
| Rpl19 | -6145 | 1844 | 1393 | 7139 | -5256 |
| Rpl21 | -5242 | 1494 | -2632 | 6613 | -7105 |
| Rpl22 | 2309 | 1493 | 135 | 7361 | -5393 |
| Rpl22l1 | -6274 | -4977 | -2367 | 6270 | -5683 |
| Rpl23 | -4886 | -1314 | -5284 | 6983 | -7403 |
| Rpl23a | -5685 | 181 | -4668 | 5986 | -6814 |
| Rpl24 | -6576 | 1391 | -3886 | 6934 | -6380 |
| Rpl26 | -6659 | 1690 | -587 | 7025 | -6436 |
| Rpl27 | -6845 | 1737 | -3419 | 6972 | -3911 |
| Rpl27a | -5517 | 3660 | -2513 | 5849 | -4735 |
| Rpl28 | -1279 | 5641 | -1248 | 5705 | -5460 |
| Rpl29 | -1125 | 4140 | -4187 | 6593 | -5922 |
| Rpl3 | -4393 | 97 | 1158 | 6008 | -4443 |
| Rpl30 | -3489 | -1769 | -4305 | 6489 | -7269 |
| Rpl31 | -6836 | -3203 | -1412 | 7055 | -6596 |
| Rpl32 | -4734 | -2231 | 1048 | 7325 | -5634 |
| Rpl34 | -5472 | -4039 | -1304 | 7052 | -5665 |
| Rpl35 | -5746 | -5044 | -3769 | 7203 | -6944 |
| Rpl35a | -5482 | -3840 | 570 | 7450 | -6779 |
| Rpl36 | -4150 | -526 | -925 | 7394 | -6244 |
| Rpl36a | -5737 | 966 | -3217 | 6846 | -6933 |
| Rpl36al | -5513 | 1911 | -471 | 7142 | -7041 |
| Rpl37 | -4803 | -2009 | -157 | 7169 | -7308 |
| Rpl37a | -5196 | -2693 | 70 | 7353 | -7233 |
| Rpl38 | -4285 | -3890 | 857 | 7427 | -7458 |
| Rpl39 | -6226 | -2451 | 1477 | 7435 | -7398 |
| Rpl4 | -4925 | 1852 | -4074 | 6135 | -4712 |
| Rpl5 | 5744 | -2476 | -3141 | 5665 | 42 |
| Rpl6 | -5411 | 5527 | -1164 | 5021 | -4217 |
| Rpl7 | -5113 | 1762 | 151 | 6242 | -4040 |
| Rpl7a | -3564 | 4076 | 1931 | 6938 | -2667 |
| Rpl8 | -3703 | 3543 | -3664 | 6481 | -4491 |
| Rpl9 | -5504 | 344 | 903 | 6756 | -2526 |
| Rplp0 | -3763 | 4412 | -942 | 6357 | 956 |
| Rplp1 | -3659 | -3603 | -814 | 6990 | -6512 |
| Rplp2 | -1405 | 721 | 5081 | 7200 | -5799 |
| Rpn1 | -4337 | -7680 | -5653 | 954 | -6688 |
| Rpn2 | 567 | 2281 | -341 | -1514 | -2629 |
| Rps10 | -5436 | 1596 | -1596 | 7118 | -2524 |
| Rps11 | -6088 | -966 | -1330 | 6240 | -6425 |
| Rps12 | -6536 | 2445 | -4827 | 7047 | -5574 |
| Rps13 | -2674 | -235 | -1978 | 6430 | -3919 |
| Rps14 | -3675 | 1734 | 3410 | 7146 | -3493 |
| Rps15 | -5634 | 2477 | 239 | 7130 | -5513 |
| Rps15a | 369 | 608 | -3369 | 6779 | -5204 |
| Rps16 | -4792 | 2799 | -1537 | 6267 | -5455 |
| Rps17 | -5260 | -1557 | 1246 | 7182 | -6746 |
| Rps18 | -4838 | 1158 | 194 | 6830 | -4753 |
| Rps19 | -6105 | -2857 | -5576 | 6611 | -5782 |
| Rps2 | -2017 | 387 | -812 | 6266 | -3726 |
| Rps20 | -4819 | -1197 | -4402 | 5625 | -7090 |
| Rps21 | -4549 | -3950 | -722 | 7488 | -7191 |
| Rps23 | -6959 | 2961 | -3533 | 6890 | -7067 |
| Rps24 | -6377 | -301 | -5394 | 5997 | -5015 |
| Rps25 | -6573 | -1150 | -1883 | 6238 | -5538 |
| Rps26 | -5325 | 3572 | -3697 | 5769 | -6007 |
| Rps27 | -5449 | -2098 | 2068 | 7449 | -7364 |
| Rps27a | -6372 | -7132 | -2043 | 6853 | -6401 |
| Rps27l | -4990 | -3246 | -4325 | 6048 | -3758 |
| Rps28 | -2854 | -2799 | 2837 | 7397 | -7470 |
| Rps29 | -234 | -4717 | -446 | 7482 | -7465 |
| Rps3 | -5535 | 1738 | -2705 | 6117 | -1500 |
| Rps3a1 | -6001 | 295 | -2164 | 5731 | -4251 |
| Rps4x | -3555 | -300 | -4680 | 5409 | -4453 |
| Rps5 | -4284 | 1344 | -1916 | 5993 | -4583 |
| Rps6 | -4272 | 4707 | 1599 | 6014 | -5295 |
| Rps7 | -5696 | 1849 | -3387 | 6808 | -5804 |
| Rps8 | -6704 | -566 | -5243 | 7004 | -6741 |
| Rps9 | -5004 | 1757 | -844 | 6794 | -4576 |
| Rpsa | -5034 | -2245 | -4844 | 5145 | -2970 |
| Sars | -523 | 3642 | 2351 | 4931 | 712 |
| Sars2 | 2073 | 3945 | 7679 | 4920 | 6199 |
| Sec11a | -7127 | -6550 | -5434 | 6199 | -3396 |
| Sec11c | -6474 | -2330 | -1390 | 7039 | -5441 |
| Sec61a1 | -1747 | -8379 | -6972 | 893 | -2327 |
| Sec61a2 | 2624 | -7285 | 696 | 1163 | -1570 |
| Sec61b | -3658 | 2229 | 2906 | 7337 | -6763 |
| Sec61g | -2940 | -4761 | -6122 | 6367 | 3468 |
| Spcs1 | -4369 | 1863 | -1685 | 6189 | -4700 |
| Spcs2 | -5799 | -5164 | -4098 | 4006 | -4171 |
| Spcs3 | -5662 | -7747 | 582 | 5 | 7366 |
| Srp14 | -6588 | 1875 | 1614 | 6416 | -5439 |
| Srp19 | -5268 | 6274 | -2237 | 5258 | -5856 |
| Srp54a | 1906 | -2837 | -5232 | 1541 | -2688 |
| Srp68 | 1016 | -7311 | 1841 | -1098 | 6797 |
| Srp72 | 3704 | 4824 | 509 | -5882 | 1592 |
| Srp9 | -4785 | 4091 | 702 | 6767 | -1805 |
| Srpr | 2424 | -3797 | -3773 | -5219 | 6962 |
| Srprb | -4307 | -4558 | -1862 | 4654 | -2825 |
| Ssr1 | 1409 | -340 | -3512 | -2483 | 1323 |
| Ssr2 | -3113 | 4494 | 3015 | 5354 | -290 |
| Ssr3 | -5658 | 1122 | -2992 | 2453 | 3971 |
| Ssr4 | -4733 | 232 | 2302 | 5827 | -2902 |
| Tars | -7623 | 4920 | -4975 | 330 | 3508 |
| Tars2 | -6945 | -3067 | 4884 | 2562 | -6209 |
| Tram1 | -5082 | -1901 | -2689 | -6019 | -2866 |
| Trmt112 | -2542 | 6716 | -5903 | 5218 | -6826 |
| Tsfm | -6083 | -3471 | -166 | 6095 | -696 |
| Tufm | 2 | -3435 | -3801 | 3887 | -1319 |
| Uba52 | -2504 | 5042 | 585 | 6605 | -5655 |
| Vars | -1428 | -5694 | 1092 | 508 | 2665 |
| Vars2 | -3160 | -3631 | 751 | -8173 | 797 |
| Wars | 2666 | -1822 | 6309 | 1691 | 6504 |
| Wars2 | 340 | 4354 | 3320 | -8073 | 3832 |
| Yars | -2235 | 4838 | -849 | 292 | 5851 |
| Yars2 | -444 | 474 | -1756 | 5487 | 3562 |
REGULATION OF RUNX1 EXPRESSION AND ACTIVITY
| metric | value |
|---|---|
| setSize | 17 |
| pMANOVA | 0.000183 |
| p.adjustMANOVA | 0.000997 |
| s.dist | 0.779 |
| s.hyp | 0.119 |
| s.hip | -0.429 |
| s.amy | -0.163 |
| s.pag | -0.578 |
| s.ni | -0.221 |
| p.hyp | 0.396 |
| p.hip | 0.00222 |
| p.amy | 0.244 |
| p.pag | 3.72e-05 |
| p.ni | 0.115 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | hip |
|---|---|---|
| Ago3 | -8080 | -8133 |
| Cdk6 | -7574 | -7830 |
| Ago2 | -7908 | -7293 |
| Ccnd2 | -8194 | -6065 |
| Tnrc6b | -5911 | -7367 |
| Ccnd1 | -4894 | -8575 |
| Mov10 | -8318 | -4851 |
| Cbfb | -4395 | -8324 |
| Ago4 | -4625 | -6580 |
| Pml | -3743 | -5951 |
| Src | -3308 | -2471 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Ago1 | 2610 | 2030 | -502 | -7431 | 1967 |
| Ago2 | 1116 | -7293 | -3963 | -7908 | -2195 |
| Ago3 | 3091 | -8133 | -6894 | -8080 | 2569 |
| Ago4 | -4764 | -6580 | -7719 | -4625 | 1055 |
| Cbfb | -7736 | -8324 | -6517 | -4395 | -2457 |
| Ccnd1 | -7749 | -8575 | -2004 | -4894 | -7027 |
| Ccnd2 | 1610 | -6065 | -2292 | -8194 | -6326 |
| Ccnd3 | 2906 | 389 | -171 | 82 | 1079 |
| Cdk6 | -5179 | -7830 | -4282 | -7574 | -5178 |
| Mov10 | 1802 | -4851 | 5394 | -8318 | -6862 |
| Pml | -4085 | -5951 | 2765 | -3743 | 5087 |
| Ptpn11 | 6553 | 2873 | 1961 | 2579 | 8298 |
| Runx1 | 3301 | -3005 | -3020 | 443 | -5907 |
| Src | 1566 | -2471 | 4443 | -3308 | 949 |
| Tnrc6a | 6045 | 21 | -2476 | -7314 | -1813 |
| Tnrc6b | 5903 | -7367 | -3061 | -5911 | -4397 |
| Tnrc6c | 6043 | 2308 | 6217 | -7044 | -427 |
ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K
| metric | value |
|---|---|
| setSize | 11 |
| pMANOVA | 0.00554 |
| p.adjustMANOVA | 0.0181 |
| s.dist | 0.777 |
| s.hyp | 0.151 |
| s.hip | -0.635 |
| s.amy | -0.0855 |
| s.pag | -0.402 |
| s.ni | 0.0919 |
| p.hyp | 0.385 |
| p.hip | 0.000264 |
| p.amy | 0.624 |
| p.pag | 0.0209 |
| p.ni | 0.598 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | hip | pag |
|---|---|---|
| Gab1 | -8124 | -8153 |
| Pik3cd | -7153 | -8296 |
| Jak2 | -7478 | -5348 |
| Pik3ca | -7592 | -5089 |
| Pik3cg | -5565 | -6335 |
| Pik3cb | -5251 | -3920 |
| Irs2 | -1332 | -4234 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Epor | 5719 | -5832 | 6155 | 636 | -1706 |
| Gab1 | -8041 | -8124 | -7710 | -8153 | -6979 |
| Irs2 | 1511 | -1332 | 1071 | -4234 | 3315 |
| Jak2 | -3055 | -7478 | -4974 | -5348 | 5153 |
| Lyn | -3294 | -7194 | -7606 | 2628 | 1673 |
| Pik3ca | -7579 | -7592 | -7312 | -5089 | -25 |
| Pik3cb | 1265 | -5251 | 2454 | -3920 | 4733 |
| Pik3cd | 5623 | -7153 | 6795 | -8296 | 3878 |
| Pik3cg | 7511 | -5565 | 4613 | -6335 | -136 |
| Pik3r1 | 5354 | 1098 | 1928 | -4293 | 543 |
| Pik3r5 | 6270 | -8284 | -2895 | 2392 | 3044 |
INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION
| metric | value |
|---|---|
| setSize | 12 |
| pMANOVA | 0.000169 |
| p.adjustMANOVA | 0.000928 |
| s.dist | 0.775 |
| s.hyp | 0.0314 |
| s.hip | 0.599 |
| s.amy | -0.429 |
| s.pag | 0.165 |
| s.ni | 0.169 |
| p.hyp | 0.851 |
| p.hip | 0.000325 |
| p.amy | 0.01 |
| p.pag | 0.322 |
| p.ni | 0.312 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | hip | amy |
|---|---|---|
| Pros1 | 6697 | -6566 |
| F8 | 6657 | -5904 |
| Vwf | 5512 | -6247 |
| Serpine2 | 4514 | -7197 |
| Serping1 | 7036 | -3977 |
| Serpind1 | 3258 | -5931 |
| Gp5 | 6378 | -3029 |
| C1qbp | 6114 | -1786 |
| Serpinc1 | 2102 | -3199 |
| A2m | 7332 | -134 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| A2m | 7498 | 7332 | -134 | 4005 | 7093 |
| C1qbp | -3397 | 6114 | -1786 | 6818 | -2779 |
| F8 | 1136 | 6657 | -5904 | -4104 | 3109 |
| Gp1ba | -5216 | 2836 | 7902 | -1184 | -6285 |
| Gp5 | 512 | 6378 | -3029 | 1645 | 7244 |
| Prcp | 1683 | -8538 | -5058 | 15 | 3328 |
| Pros1 | 7448 | 6697 | -6566 | 1068 | 4927 |
| Serpinc1 | -7866 | 2102 | -3199 | 295 | 399 |
| Serpind1 | -531 | 3258 | -5931 | 4959 | -2730 |
| Serpine2 | -6505 | 4514 | -7197 | 1992 | 2502 |
| Serping1 | 6485 | 7036 | -3977 | 3323 | 4054 |
| Vwf | -443 | 5512 | -6247 | -8107 | 1199 |
UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION
| metric | value |
|---|---|
| setSize | 21 |
| pMANOVA | 1.63e-05 |
| p.adjustMANOVA | 0.000114 |
| s.dist | 0.769 |
| s.hyp | 0.437 |
| s.hip | -0.278 |
| s.amy | 0.406 |
| s.pag | -0.293 |
| s.ni | 0.269 |
| p.hyp | 0.000523 |
| p.hip | 0.0277 |
| p.amy | 0.00128 |
| p.pag | 0.0203 |
| p.ni | 0.0329 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | hyp | amy |
|---|---|---|
| Camk2b | 7405 | 7585 |
| Grin2c | 7709 | 6726 |
| Camk2a | 7207 | 6629 |
| Grin2b | 7286 | 5901 |
| Gria3 | 6971 | 5958 |
| Grin2a | 7735 | 4374 |
| Dlg4 | 5080 | 6564 |
| Gria1 | 6152 | 4999 |
| Actn2 | 5000 | 5279 |
| Grin1 | 2829 | 7216 |
| Dlg3 | 2275 | 7074 |
| Camk2d | 3624 | 4117 |
| Gria2 | 2286 | 3762 |
| Lrrc7 | 1877 | 2148 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Actn2 | 5000 | -6366 | 5279 | 4139 | -6863 |
| Calm1 | -3210 | -5777 | -2383 | 480 | 4856 |
| Camk2a | 7207 | -4146 | 6629 | -5758 | 2594 |
| Camk2b | 7405 | -663 | 7585 | 1811 | -336 |
| Camk2d | 3624 | 5724 | 4117 | -6480 | 3253 |
| Camk2g | -2481 | -772 | 2753 | 2961 | 7086 |
| Dlg1 | -2526 | -6201 | 60 | -478 | 6813 |
| Dlg2 | 5792 | -4706 | -3560 | -6197 | 5701 |
| Dlg3 | 2275 | -6061 | 7074 | -4165 | 2207 |
| Dlg4 | 5080 | -6512 | 6564 | -2292 | -5284 |
| Gria1 | 6152 | -1363 | 4999 | -5220 | 2242 |
| Gria2 | 2286 | -4974 | 3762 | -6757 | -1698 |
| Gria3 | 6971 | -1023 | 5958 | -1351 | 3445 |
| Gria4 | -801 | 1234 | 113 | -548 | 6440 |
| Grin1 | 2829 | -3464 | 7216 | -4005 | 6253 |
| Grin2a | 7735 | -7350 | 4374 | -4196 | 4463 |
| Grin2b | 7286 | -6440 | 5901 | -6614 | -2727 |
| Grin2c | 7709 | 2447 | 6726 | 1345 | 8363 |
| Grin2d | -620 | 4842 | -1980 | -8301 | 495 |
| Lrrc7 | 1877 | -6764 | 2148 | -6931 | 997 |
| Nefl | -153 | -1355 | -5259 | 568 | 7113 |
REDUCTION OF CYTOSOLIC CA LEVELS
| metric | value |
|---|---|
| setSize | 11 |
| pMANOVA | 0.0131 |
| p.adjustMANOVA | 0.0362 |
| s.dist | 0.763 |
| s.hyp | 0.446 |
| s.hip | -0.173 |
| s.amy | 0.272 |
| s.pag | -0.319 |
| s.ni | 0.422 |
| p.hyp | 0.0105 |
| p.hip | 0.319 |
| p.amy | 0.119 |
| p.pag | 0.0674 |
| p.ni | 0.0153 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | hyp | ni |
|---|---|---|
| Slc8a2 | 6569 | 5983 |
| Atp2b3 | 5390 | 5646 |
| Atp2b2 | 6264 | 4247 |
| Atp2b4 | 6885 | 3657 |
| Slc8a3 | 5482 | 3119 |
| Atp2a3 | 6753 | 2080 |
| Slc8a1 | 1563 | 1725 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Atp2a2 | -1976 | -6303 | -224 | -5935 | 6375 |
| Atp2a3 | 6753 | 1343 | -1279 | 3840 | 2080 |
| Atp2b1 | 6975 | -6442 | 3895 | -6483 | -365 |
| Atp2b2 | 6264 | -5874 | 5748 | -3152 | 4247 |
| Atp2b3 | 5390 | 3211 | 4921 | -3744 | 5646 |
| Atp2b4 | 6885 | 1283 | 6673 | -6398 | 3657 |
| Calm1 | -3210 | -5777 | -2383 | 480 | 4856 |
| Slc8a1 | 1563 | -7287 | -993 | -7888 | 1725 |
| Slc8a2 | 6569 | -2683 | 7930 | -1871 | 5983 |
| Slc8a3 | 5482 | 6557 | 3827 | -3110 | 3119 |
| Sri | -3545 | -168 | -4218 | 1597 | 5179 |
TRAF6 MEDIATED IRF7 ACTIVATION
| metric | value |
|---|---|
| setSize | 15 |
| pMANOVA | 0.00331 |
| p.adjustMANOVA | 0.0118 |
| s.dist | 0.756 |
| s.hyp | -0.176 |
| s.hip | -0.448 |
| s.amy | -0.385 |
| s.pag | -0.435 |
| s.ni | 0.0476 |
| p.hyp | 0.238 |
| p.hip | 0.00264 |
| p.amy | 0.00989 |
| p.pag | 0.00354 |
| p.ni | 0.75 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | hip | pag |
|---|---|---|
| Traf6 | -7975 | -6680 |
| Tank | -5853 | -7580 |
| Ddx58 | -8007 | -5179 |
| Crebbp | -6540 | -5698 |
| Sike1 | -6022 | -5176 |
| Ifih1 | -2770 | -8045 |
| Ikbke | -4995 | -3261 |
| Ep300 | -3349 | -4410 |
| Trim25 | -4288 | -3104 |
| Irf3 | -5376 | -1185 |
| Mavs | -1071 | -4923 |
| Traf2 | -6830 | -546 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Crebbp | 5856 | -6540 | 2739 | -5698 | -6903 |
| Ddx58 | -4298 | -8007 | -2124 | -5179 | -3533 |
| Ep300 | 1346 | -3349 | -2137 | -4410 | 4066 |
| Ifih1 | 890 | -2770 | -7809 | -8045 | -1905 |
| Ikbke | -657 | -4995 | 4371 | -3261 | 1491 |
| Irf3 | -5768 | -5376 | -1103 | -1185 | -7110 |
| Irf7 | 1101 | -8554 | -7597 | 2262 | -3028 |
| Mavs | -3159 | -1071 | -1657 | -4923 | 6917 |
| Rnf135 | -1744 | 5488 | -4242 | -1281 | 5257 |
| Sike1 | -7550 | -6022 | -3240 | -5176 | 3017 |
| Tank | 4790 | -5853 | -5596 | -7580 | 2567 |
| Tbk1 | -6450 | 3020 | -5564 | -3672 | 2664 |
| Traf2 | -4243 | -6830 | -2475 | -546 | 3234 |
| Traf6 | -5007 | -7975 | -7299 | -6680 | 1626 |
| Trim25 | 1053 | -4288 | -2307 | -3104 | 4725 |
TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS
| metric | value |
|---|---|
| setSize | 17 |
| pMANOVA | 0.000481 |
| p.adjustMANOVA | 0.00238 |
| s.dist | 0.747 |
| s.hyp | 0.441 |
| s.hip | -0.1 |
| s.amy | 0.554 |
| s.pag | -0.112 |
| s.ni | 0.185 |
| p.hyp | 0.00166 |
| p.hip | 0.475 |
| p.amy | 7.59e-05 |
| p.pag | 0.422 |
| p.ni | 0.186 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | amy | hyp |
|---|---|---|
| Prkca | 7641 | 7016 |
| Prkcb | 6373 | 7139 |
| Ap2b1 | 6698 | 6226 |
| Gria3 | 5958 | 6971 |
| Prkcg | 7502 | 5151 |
| Gria1 | 4999 | 6152 |
| Grip1 | 4296 | 7154 |
| Nsf | 6748 | 4475 |
| Ap2a1 | 6991 | 3934 |
| Gria2 | 3762 | 2286 |
| Pick1 | 5438 | 1459 |
| Ap2m1 | 5424 | 518 |
| Tspan7 | 1366 | 746 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Ap2a1 | 3934 | 1830 | 6991 | -1974 | 5077 |
| Ap2a2 | -1706 | -4789 | 6011 | -5001 | -641 |
| Ap2b1 | 6226 | -5242 | 6698 | -7093 | 5463 |
| Ap2m1 | 518 | 2917 | 5424 | 3094 | -1755 |
| Ap2s1 | -3830 | 2556 | 2408 | 7263 | -4706 |
| Gria1 | 6152 | -1363 | 4999 | -5220 | 2242 |
| Gria2 | 2286 | -4974 | 3762 | -6757 | -1698 |
| Gria3 | 6971 | -1023 | 5958 | -1351 | 3445 |
| Gria4 | -801 | 1234 | 113 | -548 | 6440 |
| Grip1 | 7154 | 2620 | 4296 | -5290 | 6586 |
| Grip2 | 3797 | 2974 | -6456 | -2101 | 107 |
| Nsf | 4475 | 2098 | 6748 | -3951 | 5358 |
| Pick1 | 1459 | -947 | 5438 | 4655 | -883 |
| Prkca | 7016 | -4785 | 7641 | -3036 | 791 |
| Prkcb | 7139 | -8077 | 6373 | -1079 | 3865 |
| Prkcg | 5151 | -4630 | 7502 | 2894 | 3849 |
| Tspan7 | 746 | -4643 | 1366 | 2999 | -39 |
LONG TERM POTENTIATION
| metric | value |
|---|---|
| setSize | 23 |
| pMANOVA | 1.26e-05 |
| p.adjustMANOVA | 8.91e-05 |
| s.dist | 0.743 |
| s.hyp | 0.442 |
| s.hip | -0.289 |
| s.amy | 0.325 |
| s.pag | -0.328 |
| s.ni | 0.246 |
| p.hyp | 0.000244 |
| p.hip | 0.0165 |
| p.amy | 0.007 |
| p.pag | 0.0065 |
| p.ni | 0.041 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | hyp | pag |
|---|---|---|
| Grin2b | 7286 | -6614 |
| Camk2a | 7207 | -5758 |
| Erbb4 | 4764 | -7731 |
| Dlg2 | 5792 | -6197 |
| Grin2a | 7735 | -4196 |
| Gria1 | 6152 | -5220 |
| Camk2d | 3624 | -6480 |
| Gria2 | 2286 | -6757 |
| Lrrc7 | 1877 | -6931 |
| Dlg4 | 5080 | -2292 |
| Grin1 | 2829 | -4005 |
| Dlg3 | 2275 | -4165 |
| Src | 1566 | -3308 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Actn2 | 5000 | -6366 | 5279 | 4139 | -6863 |
| Calm1 | -3210 | -5777 | -2383 | 480 | 4856 |
| Camk2a | 7207 | -4146 | 6629 | -5758 | 2594 |
| Camk2b | 7405 | -663 | 7585 | 1811 | -336 |
| Camk2d | 3624 | 5724 | 4117 | -6480 | 3253 |
| Camk2g | -2481 | -772 | 2753 | 2961 | 7086 |
| Dlg1 | -2526 | -6201 | 60 | -478 | 6813 |
| Dlg2 | 5792 | -4706 | -3560 | -6197 | 5701 |
| Dlg3 | 2275 | -6061 | 7074 | -4165 | 2207 |
| Dlg4 | 5080 | -6512 | 6564 | -2292 | -5284 |
| Erbb4 | 4764 | -3200 | -5392 | -7731 | 4128 |
| Gria1 | 6152 | -1363 | 4999 | -5220 | 2242 |
| Gria2 | 2286 | -4974 | 3762 | -6757 | -1698 |
| Grin1 | 2829 | -3464 | 7216 | -4005 | 6253 |
| Grin2a | 7735 | -7350 | 4374 | -4196 | 4463 |
| Grin2b | 7286 | -6440 | 5901 | -6614 | -2727 |
| Grin2c | 7709 | 2447 | 6726 | 1345 | 8363 |
| Grin2d | -620 | 4842 | -1980 | -8301 | 495 |
| Lrrc7 | 1877 | -6764 | 2148 | -6931 | 997 |
| Nefl | -153 | -1355 | -5259 | 568 | 7113 |
| Nrg1 | -383 | 1943 | -4617 | -3849 | 4042 |
| Nrgn | 7671 | -3823 | 3249 | 1016 | 1864 |
| Src | 1566 | -2471 | 4443 | -3308 | 949 |
INFLUENZA INFECTION
| metric | value |
|---|---|
| setSize | 145 |
| pMANOVA | 1.16e-41 |
| p.adjustMANOVA | 8.32e-40 |
| s.dist | 0.742 |
| s.hyp | -0.358 |
| s.hip | -0.0182 |
| s.amy | -0.108 |
| s.pag | 0.481 |
| s.ni | -0.423 |
| p.hyp | 9.47e-14 |
| p.hip | 0.705 |
| p.amy | 0.0255 |
| p.pag | 1.38e-23 |
| p.ni | 1.44e-18 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | ni |
|---|---|---|
| Rps29 | 7482 | -7465 |
| Rpl38 | 7427 | -7458 |
| Rps28 | 7397 | -7470 |
| Rpl39 | 7435 | -7398 |
| Rps27 | 7449 | -7364 |
| Rps21 | 7488 | -7191 |
| Rpl37a | 7353 | -7233 |
| Rpl37 | 7169 | -7308 |
| Rpl23 | 6983 | -7403 |
| Polr2l | 7528 | -6805 |
| Rpl35a | 7450 | -6779 |
| Rpl36al | 7142 | -7041 |
| Rpl35 | 7203 | -6944 |
| Rps23 | 6890 | -7067 |
| Rps17 | 7182 | -6746 |
| Rpl36a | 6846 | -6933 |
| Rps8 | 7004 | -6741 |
| Rpl30 | 6489 | -7269 |
| Rpl21 | 6613 | -7105 |
| Rpl31 | 7055 | -6596 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Aaas | 4363 | -8487 | 7277 | 5048 | -92 |
| Calr | -7354 | -8556 | -7756 | -5638 | -7238 |
| Canx | -7011 | -5031 | -5978 | -6732 | 1684 |
| Clta | -4595 | 6103 | 2764 | 5503 | 1820 |
| Cltc | 2826 | -3860 | 1130 | -5854 | 7423 |
| Cpsf4 | -4191 | 2318 | 7522 | 485 | -4897 |
| Dnajc3 | -7880 | -8438 | -7715 | -7017 | -6300 |
| Eif2ak2 | 1083 | -8497 | -5760 | -5156 | -2252 |
| Fau | -5907 | 1583 | 1608 | 7212 | -5383 |
| Grsf1 | -2021 | 5790 | -3781 | 5932 | 8315 |
| Gtf2f1 | -3167 | -2326 | -184 | 2998 | -5874 |
| Gtf2f2 | -3094 | 6028 | -3706 | 5835 | -4944 |
| Hsp90aa1 | -7973 | -8277 | -7326 | -4822 | -6162 |
| Hspa1a | -8073 | -7910 | -7847 | -7813 | -6471 |
| Ipo5 | -1721 | -4846 | 5723 | -1504 | 3815 |
| Isg15 | -7974 | -8027 | -7403 | -6299 | -7037 |
| Kpna1 | 299 | -5696 | -5744 | -4704 | 4121 |
| Kpna2 | -1424 | -416 | 7080 | 3403 | -2875 |
| Kpna3 | -8004 | -2762 | -3870 | -7295 | 8410 |
| Kpna4 | -7561 | -6154 | 1200 | -3862 | 8252 |
| Kpnb1 | 480 | -3912 | -2013 | -6343 | 3235 |
| Ndc1 | 2868 | -5533 | 229 | -2020 | 7825 |
| Nup107 | 538 | 3895 | 6063 | 3867 | -402 |
| Nup133 | 2288 | -893 | 4438 | -5990 | 3285 |
| Nup153 | 4933 | -1425 | -3469 | -2437 | 4524 |
| Nup155 | 5907 | -5530 | -478 | -8029 | 4440 |
| Nup160 | 3120 | -1981 | -4176 | -3256 | 185 |
| Nup188 | 6629 | 233 | 7890 | -2605 | 7217 |
| Nup205 | 1772 | -6620 | -358 | -7752 | 3623 |
| Nup210 | 5309 | -6242 | 5471 | -7252 | 5831 |
| Nup214 | 1828 | 355 | 1352 | -4033 | -2669 |
| Nup35 | -8019 | -2953 | 573 | 2525 | -1663 |
| Nup37 | -1215 | 1701 | -195 | -3269 | -5321 |
| Nup43 | -5256 | -638 | -2168 | 1237 | -1850 |
| Nup50 | -4592 | -6667 | -3076 | -6415 | 5209 |
| Nup54 | 3600 | -668 | -5336 | 7194 | -852 |
| Nup62 | -1948 | -3440 | -1398 | 1316 | 2609 |
| Nup85 | -148 | -3865 | -105 | 4250 | 3474 |
| Nup88 | -2564 | -2100 | 5085 | 760 | -1667 |
| Nup93 | 2223 | -3501 | 6729 | -3143 | -1784 |
| Nup98 | 5204 | -1666 | -5694 | -5558 | 1832 |
| Nupl2 | -1949 | -1195 | -2640 | -1238 | -2834 |
| Pabpn1 | -2254 | -2042 | 5228 | 1735 | -4058 |
| Parp1 | 5167 | 3458 | 7133 | -622 | 5612 |
| Polr2a | 3817 | 3195 | 7005 | -6110 | 2386 |
| Polr2b | 1859 | -3814 | 2977 | -2350 | 6139 |
| Polr2c | -3665 | -1067 | -351 | 4861 | -1046 |
| Polr2d | 3856 | 4361 | -1374 | 3601 | -3607 |
| Polr2e | -3033 | 3580 | 5937 | 6359 | -3867 |
| Polr2f | -5573 | -562 | -4059 | 7274 | -5382 |
| Polr2g | -3741 | 1232 | 1513 | 6731 | -4181 |
| Polr2h | -1953 | -4743 | 88 | 6981 | -1618 |
| Polr2i | -6096 | -5148 | -579 | 7432 | -3750 |
| Polr2j | -2039 | 778 | 3581 | 7384 | -1213 |
| Polr2k | -3217 | -284 | 1604 | 6714 | -6154 |
| Polr2l | -2702 | -1272 | 3622 | 7528 | -6805 |
| Pom121 | -950 | -2392 | 4175 | -7006 | 5568 |
| Rae1 | 1118 | 1246 | 7492 | 6151 | -298 |
| Ran | -6118 | -248 | 2932 | 4916 | -2388 |
| Ranbp2 | 1731 | -6073 | -5964 | -6211 | 7830 |
| Rpl10 | 7552 | 2305 | -6483 | 1980 | 1798 |
| Rpl10a | -4754 | 5887 | -3904 | 6315 | -6264 |
| Rpl11 | -7040 | -1610 | -1752 | 7106 | -5100 |
| Rpl12 | -1293 | 111 | -1276 | 5593 | -4815 |
| Rpl13 | -5435 | 705 | -309 | 7111 | -4751 |
| Rpl13a | -6127 | -800 | -4926 | 6137 | -3678 |
| Rpl14 | -4973 | 3377 | -3827 | 6231 | -6184 |
| Rpl15 | -1081 | 4664 | -97 | 5670 | -5225 |
| Rpl17 | -6154 | 1812 | -4356 | 5972 | -3587 |
| Rpl18 | -3623 | 1407 | 1250 | 6814 | -5632 |
| Rpl18a | -1090 | 3984 | -5189 | 6777 | -4423 |
| Rpl19 | -6145 | 1844 | 1393 | 7139 | -5256 |
| Rpl21 | -5242 | 1494 | -2632 | 6613 | -7105 |
| Rpl22 | 2309 | 1493 | 135 | 7361 | -5393 |
| Rpl22l1 | -6274 | -4977 | -2367 | 6270 | -5683 |
| Rpl23 | -4886 | -1314 | -5284 | 6983 | -7403 |
| Rpl23a | -5685 | 181 | -4668 | 5986 | -6814 |
| Rpl24 | -6576 | 1391 | -3886 | 6934 | -6380 |
| Rpl26 | -6659 | 1690 | -587 | 7025 | -6436 |
| Rpl27 | -6845 | 1737 | -3419 | 6972 | -3911 |
| Rpl27a | -5517 | 3660 | -2513 | 5849 | -4735 |
| Rpl28 | -1279 | 5641 | -1248 | 5705 | -5460 |
| Rpl29 | -1125 | 4140 | -4187 | 6593 | -5922 |
| Rpl3 | -4393 | 97 | 1158 | 6008 | -4443 |
| Rpl30 | -3489 | -1769 | -4305 | 6489 | -7269 |
| Rpl31 | -6836 | -3203 | -1412 | 7055 | -6596 |
| Rpl32 | -4734 | -2231 | 1048 | 7325 | -5634 |
| Rpl34 | -5472 | -4039 | -1304 | 7052 | -5665 |
| Rpl35 | -5746 | -5044 | -3769 | 7203 | -6944 |
| Rpl35a | -5482 | -3840 | 570 | 7450 | -6779 |
| Rpl36 | -4150 | -526 | -925 | 7394 | -6244 |
| Rpl36a | -5737 | 966 | -3217 | 6846 | -6933 |
| Rpl36al | -5513 | 1911 | -471 | 7142 | -7041 |
| Rpl37 | -4803 | -2009 | -157 | 7169 | -7308 |
| Rpl37a | -5196 | -2693 | 70 | 7353 | -7233 |
| Rpl38 | -4285 | -3890 | 857 | 7427 | -7458 |
| Rpl39 | -6226 | -2451 | 1477 | 7435 | -7398 |
| Rpl4 | -4925 | 1852 | -4074 | 6135 | -4712 |
| Rpl5 | 5744 | -2476 | -3141 | 5665 | 42 |
| Rpl6 | -5411 | 5527 | -1164 | 5021 | -4217 |
| Rpl7 | -5113 | 1762 | 151 | 6242 | -4040 |
| Rpl7a | -3564 | 4076 | 1931 | 6938 | -2667 |
| Rpl8 | -3703 | 3543 | -3664 | 6481 | -4491 |
| Rpl9 | -5504 | 344 | 903 | 6756 | -2526 |
| Rplp0 | -3763 | 4412 | -942 | 6357 | 956 |
| Rplp1 | -3659 | -3603 | -814 | 6990 | -6512 |
| Rplp2 | -1405 | 721 | 5081 | 7200 | -5799 |
| Rps10 | -5436 | 1596 | -1596 | 7118 | -2524 |
| Rps11 | -6088 | -966 | -1330 | 6240 | -6425 |
| Rps12 | -6536 | 2445 | -4827 | 7047 | -5574 |
| Rps13 | -2674 | -235 | -1978 | 6430 | -3919 |
| Rps14 | -3675 | 1734 | 3410 | 7146 | -3493 |
| Rps15 | -5634 | 2477 | 239 | 7130 | -5513 |
| Rps15a | 369 | 608 | -3369 | 6779 | -5204 |
| Rps16 | -4792 | 2799 | -1537 | 6267 | -5455 |
| Rps17 | -5260 | -1557 | 1246 | 7182 | -6746 |
| Rps18 | -4838 | 1158 | 194 | 6830 | -4753 |
| Rps19 | -6105 | -2857 | -5576 | 6611 | -5782 |
| Rps2 | -2017 | 387 | -812 | 6266 | -3726 |
| Rps20 | -4819 | -1197 | -4402 | 5625 | -7090 |
| Rps21 | -4549 | -3950 | -722 | 7488 | -7191 |
| Rps23 | -6959 | 2961 | -3533 | 6890 | -7067 |
| Rps24 | -6377 | -301 | -5394 | 5997 | -5015 |
| Rps25 | -6573 | -1150 | -1883 | 6238 | -5538 |
| Rps26 | -5325 | 3572 | -3697 | 5769 | -6007 |
| Rps27 | -5449 | -2098 | 2068 | 7449 | -7364 |
| Rps27a | -6372 | -7132 | -2043 | 6853 | -6401 |
| Rps27l | -4990 | -3246 | -4325 | 6048 | -3758 |
| Rps28 | -2854 | -2799 | 2837 | 7397 | -7470 |
| Rps29 | -234 | -4717 | -446 | 7482 | -7465 |
| Rps3 | -5535 | 1738 | -2705 | 6117 | -1500 |
| Rps3a1 | -6001 | 295 | -2164 | 5731 | -4251 |
| Rps4x | -3555 | -300 | -4680 | 5409 | -4453 |
| Rps5 | -4284 | 1344 | -1916 | 5993 | -4583 |
| Rps6 | -4272 | 4707 | 1599 | 6014 | -5295 |
| Rps7 | -5696 | 1849 | -3387 | 6808 | -5804 |
| Rps8 | -6704 | -566 | -5243 | 7004 | -6741 |
| Rps9 | -5004 | 1757 | -844 | 6794 | -4576 |
| Rpsa | -5034 | -2245 | -4844 | 5145 | -2970 |
| Sec13 | -6671 | 26 | 2130 | 5485 | 2317 |
| Seh1l | 5956 | -2758 | 6640 | -1124 | 7315 |
| Tgfb1 | -6806 | -4580 | -5587 | -452 | -787 |
| Tpr | 5291 | 4009 | 3004 | -6130 | -2851 |
| Uba52 | -2504 | 5042 | 585 | 6605 | -5655 |
| Xpo1 | -6754 | -6101 | -6977 | -7724 | -1601 |
SYNAPTIC ADHESION LIKE MOLECULES
| metric | value |
|---|---|
| setSize | 21 |
| pMANOVA | 7.75e-06 |
| p.adjustMANOVA | 5.95e-05 |
| s.dist | 0.742 |
| s.hyp | 0.328 |
| s.hip | -0.123 |
| s.amy | 0.52 |
| s.pag | -0.371 |
| s.ni | 0.143 |
| p.hyp | 0.0092 |
| p.hip | 0.33 |
| p.amy | 3.74e-05 |
| p.pag | 0.00326 |
| p.ni | 0.255 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | amy | pag |
|---|---|---|
| Lrfn4 | 7556 | -6403 |
| Lrfn2 | 5941 | -7845 |
| Grin2b | 5901 | -6614 |
| Ptprs | 7372 | -4961 |
| Dlg3 | 7074 | -4165 |
| Grin1 | 7216 | -4005 |
| Gria1 | 4999 | -5220 |
| Lrfn1 | 5193 | -3950 |
| Grin2a | 4374 | -4196 |
| Ptprf | 2682 | -6156 |
| Dlg4 | 6564 | -2292 |
| Lrfn3 | 3009 | -3870 |
| Gria3 | 5958 | -1351 |
| Ptprd | 260 | -6909 |
| Rtn3 | 2018 | -737 |
| Gria4 | 113 | -548 |
| Dlg1 | 60 | -478 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Dlg1 | -2526 | -6201 | 60 | -478 | 6813 |
| Dlg3 | 2275 | -6061 | 7074 | -4165 | 2207 |
| Dlg4 | 5080 | -6512 | 6564 | -2292 | -5284 |
| Flot1 | -3466 | 4632 | 3600 | 4649 | -5860 |
| Flot2 | 1883 | 2462 | 2524 | 904 | 6272 |
| Gria1 | 6152 | -1363 | 4999 | -5220 | 2242 |
| Gria3 | 6971 | -1023 | 5958 | -1351 | 3445 |
| Gria4 | -801 | 1234 | 113 | -548 | 6440 |
| Grin1 | 2829 | -3464 | 7216 | -4005 | 6253 |
| Grin2a | 7735 | -7350 | 4374 | -4196 | 4463 |
| Grin2b | 7286 | -6440 | 5901 | -6614 | -2727 |
| Grin2c | 7709 | 2447 | 6726 | 1345 | 8363 |
| Grin2d | -620 | 4842 | -1980 | -8301 | 495 |
| Lrfn1 | 4194 | 3315 | 5193 | -3950 | -1794 |
| Lrfn2 | 469 | 3139 | 5941 | -7845 | -5676 |
| Lrfn3 | -2668 | 2205 | 3009 | -3870 | 4730 |
| Lrfn4 | -945 | -7112 | 7556 | -6403 | -2997 |
| Ptprd | 2934 | -5616 | 260 | -6909 | -2463 |
| Ptprf | 143 | -103 | 2682 | -6156 | 7921 |
| Ptprs | 5976 | -4907 | 7372 | -4961 | -1833 |
| Rtn3 | 568 | -1898 | 2018 | -737 | 3370 |
CELLULAR RESPONSE TO STARVATION
| metric | value |
|---|---|
| setSize | 145 |
| pMANOVA | 3.07e-43 |
| p.adjustMANOVA | 2.35e-41 |
| s.dist | 0.741 |
| s.hyp | -0.304 |
| s.hip | 0.0548 |
| s.amy | -0.0622 |
| s.pag | 0.571 |
| s.ni | -0.351 |
| p.hyp | 2.59e-10 |
| p.hip | 0.256 |
| p.amy | 0.197 |
| p.pag | 1.47e-32 |
| p.ni | 3.19e-13 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | ni |
|---|---|---|
| Rps29 | 7482 | -7465 |
| Rpl38 | 7427 | -7458 |
| Rps28 | 7397 | -7470 |
| Rpl39 | 7435 | -7398 |
| Rps27 | 7449 | -7364 |
| Rps21 | 7488 | -7191 |
| Rpl37a | 7353 | -7233 |
| Rpl37 | 7169 | -7308 |
| Rpl23 | 6983 | -7403 |
| Rpl35a | 7450 | -6779 |
| Rpl36al | 7142 | -7041 |
| Rpl35 | 7203 | -6944 |
| Rps23 | 6890 | -7067 |
| Rps17 | 7182 | -6746 |
| Rpl36a | 6846 | -6933 |
| Rps8 | 7004 | -6741 |
| Rpl30 | 6489 | -7269 |
| Rpl21 | 6613 | -7105 |
| Rpl31 | 7055 | -6596 |
| Rpl36 | 7394 | -6244 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Asns | 3882 | -6268 | 3921 | -1608 | 3670 |
| Atf2 | -2259 | -2053 | -1225 | -6889 | 4100 |
| Atf3 | -7700 | -7800 | -7270 | 402 | -7377 |
| Atf4 | -5109 | -7556 | -3593 | 7029 | -2762 |
| Atp6v0b | -3000 | -1762 | 1490 | 6318 | -2278 |
| Atp6v0c | 145 | -1137 | 3074 | 3296 | 219 |
| Atp6v0d1 | -39 | -4833 | 3798 | 4934 | 6676 |
| Atp6v0e | 5140 | 6072 | -6401 | 2015 | 2433 |
| Atp6v0e2 | 477 | -2581 | 5428 | 3773 | 3497 |
| Atp6v1a | -1185 | -812 | 5469 | -1248 | 7878 |
| Atp6v1b2 | 1049 | 12 | 6325 | 869 | 6938 |
| Atp6v1c1 | -898 | -691 | 2911 | 4143 | 3126 |
| Atp6v1c2 | -1034 | -4211 | 2675 | 521 | -1897 |
| Atp6v1d | -1791 | 495 | 1290 | 3907 | -1481 |
| Atp6v1e1 | -3768 | 565 | 3013 | 6219 | 3572 |
| Atp6v1f | -2563 | 3657 | 273 | 6975 | -1012 |
| Atp6v1g1 | -3855 | 680 | -2093 | 6727 | -4612 |
| Atp6v1g2 | 3736 | 4687 | 1585 | 4719 | 3383 |
| Atp6v1h | -6205 | -3480 | -831 | 3446 | 4328 |
| BC048403 | 151 | -2703 | 2234 | 2083 | -2305 |
| Bmt2 | -5593 | -8361 | -5925 | -6337 | 2224 |
| Castor1 | 7102 | 5723 | 7838 | 7343 | 8364 |
| Castor2 | 2568 | -7866 | -4860 | -7009 | -4853 |
| Cebpb | 1867 | 5859 | 3905 | 1566 | 1301 |
| Cebpg | -5947 | -3335 | -491 | -484 | -5918 |
| Ddit3 | -8087 | -8557 | -6904 | 5070 | -7401 |
| Depdc5 | 5572 | -3737 | 3429 | -4667 | 5957 |
| Eif2ak4 | 6067 | 4810 | 662 | -4836 | -2491 |
| Eif2s1 | -6701 | -39 | -1217 | 5813 | 2921 |
| Eif2s2 | -4538 | -2403 | -5282 | 4050 | -5700 |
| Eif2s3x | 17 | -3878 | -3881 | -646 | 1396 |
| Fau | -5907 | 1583 | 1608 | 7212 | -5383 |
| Flcn | 5743 | -2266 | -346 | -5501 | 53 |
| Fnip1 | -4412 | -6859 | -3479 | -6049 | 6825 |
| Fnip2 | 6803 | 3397 | 4956 | -1206 | 3774 |
| Gcn1 | 6541 | -4336 | 5274 | -6548 | 2059 |
| Impact | -6033 | 2687 | -5811 | -5272 | -4307 |
| Itfg2 | -3020 | 4730 | 4745 | 308 | -3783 |
| Kptn | 6575 | 2041 | 5484 | 6206 | 1212 |
| Lamtor1 | 1167 | 3839 | 3216 | 7498 | 187 |
| Lamtor2 | -4743 | 6658 | -1673 | 6639 | -5059 |
| Lamtor3 | -6726 | 3633 | -1958 | 7249 | -1126 |
| Lamtor4 | 671 | -3520 | 2812 | 7375 | -5951 |
| Lamtor5 | -2974 | 3932 | -2210 | 6552 | 3766 |
| Mios | 2095 | 3953 | 2878 | 2720 | 4268 |
| Mlst8 | 6287 | 5034 | 7514 | 4181 | 5809 |
| Mtor | 2415 | -2947 | 6400 | -6261 | 5180 |
| Nprl2 | -6150 | -6539 | 1184 | 4710 | -3949 |
| Nprl3 | 4963 | 1718 | 7334 | -400 | 5490 |
| Rheb | -7406 | -3251 | -1847 | 3154 | -1179 |
| Rpl10 | 7552 | 2305 | -6483 | 1980 | 1798 |
| Rpl10a | -4754 | 5887 | -3904 | 6315 | -6264 |
| Rpl11 | -7040 | -1610 | -1752 | 7106 | -5100 |
| Rpl12 | -1293 | 111 | -1276 | 5593 | -4815 |
| Rpl13 | -5435 | 705 | -309 | 7111 | -4751 |
| Rpl13a | -6127 | -800 | -4926 | 6137 | -3678 |
| Rpl14 | -4973 | 3377 | -3827 | 6231 | -6184 |
| Rpl15 | -1081 | 4664 | -97 | 5670 | -5225 |
| Rpl17 | -6154 | 1812 | -4356 | 5972 | -3587 |
| Rpl18 | -3623 | 1407 | 1250 | 6814 | -5632 |
| Rpl18a | -1090 | 3984 | -5189 | 6777 | -4423 |
| Rpl19 | -6145 | 1844 | 1393 | 7139 | -5256 |
| Rpl21 | -5242 | 1494 | -2632 | 6613 | -7105 |
| Rpl22 | 2309 | 1493 | 135 | 7361 | -5393 |
| Rpl22l1 | -6274 | -4977 | -2367 | 6270 | -5683 |
| Rpl23 | -4886 | -1314 | -5284 | 6983 | -7403 |
| Rpl23a | -5685 | 181 | -4668 | 5986 | -6814 |
| Rpl24 | -6576 | 1391 | -3886 | 6934 | -6380 |
| Rpl26 | -6659 | 1690 | -587 | 7025 | -6436 |
| Rpl27 | -6845 | 1737 | -3419 | 6972 | -3911 |
| Rpl27a | -5517 | 3660 | -2513 | 5849 | -4735 |
| Rpl28 | -1279 | 5641 | -1248 | 5705 | -5460 |
| Rpl29 | -1125 | 4140 | -4187 | 6593 | -5922 |
| Rpl3 | -4393 | 97 | 1158 | 6008 | -4443 |
| Rpl30 | -3489 | -1769 | -4305 | 6489 | -7269 |
| Rpl31 | -6836 | -3203 | -1412 | 7055 | -6596 |
| Rpl32 | -4734 | -2231 | 1048 | 7325 | -5634 |
| Rpl34 | -5472 | -4039 | -1304 | 7052 | -5665 |
| Rpl35 | -5746 | -5044 | -3769 | 7203 | -6944 |
| Rpl35a | -5482 | -3840 | 570 | 7450 | -6779 |
| Rpl36 | -4150 | -526 | -925 | 7394 | -6244 |
| Rpl36a | -5737 | 966 | -3217 | 6846 | -6933 |
| Rpl36al | -5513 | 1911 | -471 | 7142 | -7041 |
| Rpl37 | -4803 | -2009 | -157 | 7169 | -7308 |
| Rpl37a | -5196 | -2693 | 70 | 7353 | -7233 |
| Rpl38 | -4285 | -3890 | 857 | 7427 | -7458 |
| Rpl39 | -6226 | -2451 | 1477 | 7435 | -7398 |
| Rpl4 | -4925 | 1852 | -4074 | 6135 | -4712 |
| Rpl5 | 5744 | -2476 | -3141 | 5665 | 42 |
| Rpl6 | -5411 | 5527 | -1164 | 5021 | -4217 |
| Rpl7 | -5113 | 1762 | 151 | 6242 | -4040 |
| Rpl7a | -3564 | 4076 | 1931 | 6938 | -2667 |
| Rpl8 | -3703 | 3543 | -3664 | 6481 | -4491 |
| Rpl9 | -5504 | 344 | 903 | 6756 | -2526 |
| Rplp0 | -3763 | 4412 | -942 | 6357 | 956 |
| Rplp1 | -3659 | -3603 | -814 | 6990 | -6512 |
| Rplp2 | -1405 | 721 | 5081 | 7200 | -5799 |
| Rps10 | -5436 | 1596 | -1596 | 7118 | -2524 |
| Rps11 | -6088 | -966 | -1330 | 6240 | -6425 |
| Rps12 | -6536 | 2445 | -4827 | 7047 | -5574 |
| Rps13 | -2674 | -235 | -1978 | 6430 | -3919 |
| Rps14 | -3675 | 1734 | 3410 | 7146 | -3493 |
| Rps15 | -5634 | 2477 | 239 | 7130 | -5513 |
| Rps15a | 369 | 608 | -3369 | 6779 | -5204 |
| Rps16 | -4792 | 2799 | -1537 | 6267 | -5455 |
| Rps17 | -5260 | -1557 | 1246 | 7182 | -6746 |
| Rps18 | -4838 | 1158 | 194 | 6830 | -4753 |
| Rps19 | -6105 | -2857 | -5576 | 6611 | -5782 |
| Rps2 | -2017 | 387 | -812 | 6266 | -3726 |
| Rps20 | -4819 | -1197 | -4402 | 5625 | -7090 |
| Rps21 | -4549 | -3950 | -722 | 7488 | -7191 |
| Rps23 | -6959 | 2961 | -3533 | 6890 | -7067 |
| Rps24 | -6377 | -301 | -5394 | 5997 | -5015 |
| Rps25 | -6573 | -1150 | -1883 | 6238 | -5538 |
| Rps26 | -5325 | 3572 | -3697 | 5769 | -6007 |
| Rps27 | -5449 | -2098 | 2068 | 7449 | -7364 |
| Rps27a | -6372 | -7132 | -2043 | 6853 | -6401 |
| Rps27l | -4990 | -3246 | -4325 | 6048 | -3758 |
| Rps28 | -2854 | -2799 | 2837 | 7397 | -7470 |
| Rps29 | -234 | -4717 | -446 | 7482 | -7465 |
| Rps3 | -5535 | 1738 | -2705 | 6117 | -1500 |
| Rps3a1 | -6001 | 295 | -2164 | 5731 | -4251 |
| Rps4x | -3555 | -300 | -4680 | 5409 | -4453 |
| Rps5 | -4284 | 1344 | -1916 | 5993 | -4583 |
| Rps6 | -4272 | 4707 | 1599 | 6014 | -5295 |
| Rps7 | -5696 | 1849 | -3387 | 6808 | -5804 |
| Rps8 | -6704 | -566 | -5243 | 7004 | -6741 |
| Rps9 | -5004 | 1757 | -844 | 6794 | -4576 |
| Rpsa | -5034 | -2245 | -4844 | 5145 | -2970 |
| Rptor | 6686 | -4137 | 1965 | -2648 | 4861 |
| Rraga | -1623 | 5834 | 5023 | 3891 | 7496 |
| Rragb | -6612 | 4331 | -3303 | -820 | 8005 |
| Rragc | -1332 | 2540 | 741 | 3185 | 6898 |
| Rragd | 3025 | -2221 | 2462 | -7705 | 2210 |
| Sec13 | -6671 | 26 | 2130 | 5485 | 2317 |
| Seh1l | 5956 | -2758 | 6640 | -1124 | 7315 |
| Sesn1 | 7194 | 6134 | 5956 | 6550 | 8078 |
| Sesn2 | -4224 | 3362 | 1036 | -1356 | 7789 |
| Sh3bp4 | -2801 | -1511 | 1806 | -5155 | 5210 |
| Slc38a9 | 7303 | -8458 | -6912 | -6778 | 1819 |
| Szt2 | 4344 | -7338 | 5210 | -6771 | 1067 |
| Tcirg1 | -4684 | -8053 | -6719 | -5195 | -6414 |
| Uba52 | -2504 | 5042 | 585 | 6605 | -5655 |
| Wdr24 | -3303 | -907 | 5934 | 1687 | 5 |
| Wdr59 | 4373 | -4347 | -1108 | -3400 | 2856 |
PKA MEDIATED PHOSPHORYLATION OF CREB
| metric | value |
|---|---|
| setSize | 19 |
| pMANOVA | 5.46e-05 |
| p.adjustMANOVA | 0.000333 |
| s.dist | 0.74 |
| s.hyp | -0.0309 |
| s.hip | -0.386 |
| s.amy | 0.0516 |
| s.pag | -0.612 |
| s.ni | 0.145 |
| p.hyp | 0.816 |
| p.hip | 0.00358 |
| p.amy | 0.697 |
| p.pag | 3.84e-06 |
| p.ni | 0.274 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | hip |
|---|---|---|
| Creb1 | -8066 | -8363 |
| Adcy4 | -8405 | -7008 |
| Adcy3 | -7195 | -8015 |
| Adcy2 | -5988 | -6343 |
| Prkacb | -6658 | -5615 |
| Prkar2a | -8197 | -4370 |
| Prkx | -7019 | -4528 |
| Nbea | -6073 | -4254 |
| Adcy6 | -8137 | -2399 |
| Prkar2b | -3385 | -5589 |
| Adcy9 | -4061 | -3268 |
| Prkar1b | -1693 | -3433 |
| Prkar1a | -2814 | -1823 |
| Adcy1 | -569 | -5883 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Adcy1 | 6550 | -5883 | 1481 | -569 | 7791 |
| Adcy2 | 5238 | -6343 | 5164 | -5988 | 4022 |
| Adcy3 | 2809 | -8015 | 5837 | -7195 | 2370 |
| Adcy4 | -7925 | -7008 | -6394 | -8405 | -6896 |
| Adcy5 | 5698 | 1302 | 4984 | -7109 | 2333 |
| Adcy6 | 3415 | -2399 | 428 | -8137 | -2772 |
| Adcy7 | 2896 | 1967 | -689 | -8304 | 5066 |
| Adcy8 | -7137 | 349 | -3569 | -6760 | -2592 |
| Adcy9 | 4621 | -3268 | 6495 | -4061 | 4438 |
| Calm1 | -3210 | -5777 | -2383 | 480 | 4856 |
| Creb1 | -6520 | -8363 | -6284 | -8066 | 984 |
| Nbea | 5096 | -4254 | 5245 | -6073 | 5393 |
| Prkaca | 536 | 2584 | 4026 | -974 | -911 |
| Prkacb | -5780 | -5615 | -705 | -6658 | 2764 |
| Prkar1a | -1344 | -1823 | 1101 | -2814 | 7059 |
| Prkar1b | -1456 | -3433 | 5947 | -1693 | 4760 |
| Prkar2a | -6880 | -4370 | -4761 | -8197 | 4398 |
| Prkar2b | -3250 | -5589 | -1825 | -3385 | -6274 |
| Prkx | -1534 | -4528 | -6228 | -7019 | -5454 |
RRNA PROCESSING
| metric | value |
|---|---|
| setSize | 194 |
| pMANOVA | 2.68e-56 |
| p.adjustMANOVA | 3.08e-54 |
| s.dist | 0.731 |
| s.hyp | -0.29 |
| s.hip | 0.062 |
| s.amy | -0.00171 |
| s.pag | 0.544 |
| s.ni | -0.388 |
| p.hyp | 3.49e-12 |
| p.hip | 0.137 |
| p.amy | 0.967 |
| p.pag | 4.44e-39 |
| p.ni | 1.21e-20 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | ni |
|---|---|---|
| Rps29 | 7482 | -7465 |
| Rpl38 | 7427 | -7458 |
| Rps28 | 7397 | -7470 |
| Rpl39 | 7435 | -7398 |
| Rps27 | 7449 | -7364 |
| Rps21 | 7488 | -7191 |
| Rpl37a | 7353 | -7233 |
| Rpl37 | 7169 | -7308 |
| Rpl23 | 6983 | -7403 |
| Rpl35a | 7450 | -6779 |
| Rpl36al | 7142 | -7041 |
| Rpl35 | 7203 | -6944 |
| Rps23 | 6890 | -7067 |
| Rps17 | 7182 | -6746 |
| Rpl36a | 6846 | -6933 |
| Rps8 | 7004 | -6741 |
| Rpl30 | 6489 | -7269 |
| Rpl21 | 6613 | -7105 |
| Gar1 | 6495 | -7230 |
| Rpl31 | 7055 | -6596 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Bms1 | 1791 | -3928 | -3344 | -1231 | -6854 |
| Bop1 | 1767 | -5308 | 7703 | 4711 | 6961 |
| Bud23 | -4496 | -3746 | 0 | 3962 | -3803 |
| Bysl | -1930 | 3341 | 6110 | -3041 | -4039 |
| C1d | -5706 | 1498 | -958 | 2362 | -3062 |
| Csnk1d | 901 | 2905 | 3451 | -1127 | 4706 |
| Csnk1e | -1640 | -3459 | 5499 | -4321 | -4513 |
| Dcaf13 | 2760 | -8035 | 4061 | 4301 | -6677 |
| Ddx21 | 2752 | 391 | 601 | -2375 | -5811 |
| Ddx47 | -939 | -846 | 638 | 4210 | 3735 |
| Ddx49 | 2567 | 6698 | 5373 | 6835 | 4754 |
| Ddx52 | -3248 | -7088 | 1207 | 4814 | 591 |
| Dhx37 | -954 | -187 | 6139 | -2322 | 208 |
| Dimt1 | -4370 | -5082 | -4189 | -7954 | -1832 |
| Dis3 | -4989 | -4638 | -977 | -3561 | -2313 |
| Dkc1 | -2076 | -5632 | 1032 | 3311 | -6857 |
| Ebna1bp2 | -6060 | -4105 | -6260 | 3066 | -4828 |
| Elac2 | 7202 | -7852 | 7628 | 1467 | 5130 |
| Emg1 | -1800 | -2369 | 1018 | 4295 | -67 |
| Eri1 | -4276 | -7850 | -5838 | 4226 | 4492 |
| Exosc1 | -3066 | 2621 | 6782 | 3973 | 2395 |
| Exosc10 | 2714 | 4634 | 5384 | -1183 | -6170 |
| Exosc2 | -4473 | -7846 | 865 | 5584 | 4321 |
| Exosc3 | -6840 | 5875 | 2597 | 43 | -4699 |
| Exosc4 | -5315 | 6546 | 1007 | 4053 | -5408 |
| Exosc5 | 2688 | -832 | 5816 | 5713 | -486 |
| Exosc7 | -1129 | -5209 | 5349 | 5230 | -5128 |
| Exosc8 | -1139 | -398 | -2872 | 5029 | 3322 |
| Exosc9 | -3486 | -2238 | 2869 | 6215 | 2270 |
| Fau | -5907 | 1583 | 1608 | 7212 | -5383 |
| Fbl | -4809 | -6182 | 6839 | 5535 | -7325 |
| Fcf1 | -3663 | -262 | 5087 | 4986 | -3558 |
| Ftsj3 | 1413 | -5292 | 3049 | 2547 | -5416 |
| Gar1 | -190 | 1349 | 2723 | 6495 | -7230 |
| Gnl3 | -6916 | 2819 | -1866 | 4900 | -4803 |
| Heatr1 | 4085 | -7606 | 598 | -7088 | 373 |
| Hsd17b10 | -5240 | 7146 | -1105 | 6610 | 5512 |
| Imp3 | 1159 | 2252 | -555 | 6532 | -3061 |
| Imp4 | -2958 | -6670 | 2917 | 522 | -2043 |
| Isg20l2 | 5692 | -5285 | -1788 | -191 | -7146 |
| Krr1 | -2892 | -7617 | -1957 | 5088 | -7178 |
| Las1l | -2231 | -6747 | -3861 | -2578 | -5994 |
| Ltv1 | -1335 | -5573 | 3751 | 6420 | 98 |
| Mphosph10 | -6153 | -31 | -5929 | 1327 | -6957 |
| Mphosph6 | 4508 | -2853 | 5886 | 1294 | -6652 |
| Mrm1 | 6061 | 3681 | 3070 | 4474 | 8264 |
| Mrm2 | -4539 | -5644 | 640 | 4545 | 3078 |
| Mrm3 | 2116 | 4564 | -3660 | 4537 | 486 |
| Mterf4 | -4923 | -5525 | 3979 | -1483 | -5006 |
| Mtrex | -702 | -2867 | -5489 | 1739 | 4805 |
| Nat10 | 6017 | -3447 | 6716 | -4062 | -2094 |
| Ncl | -2374 | 3952 | 911 | 2596 | -6917 |
| Nhp2 | 51 | 2937 | 1786 | 6760 | -1956 |
| Nip7 | -7469 | 4466 | 5520 | 6455 | 5106 |
| Nob1 | -836 | -1530 | 2951 | 4840 | -311 |
| Noc4l | 5041 | 4363 | 6409 | 2214 | 6809 |
| Nol11 | 1182 | 4194 | 2640 | 1482 | 6318 |
| Nol12 | 430 | -770 | 378 | 6557 | -5603 |
| Nol6 | 6109 | -1544 | 6597 | -4969 | 4557 |
| Nol9 | 5988 | 994 | 5703 | -2813 | 7025 |
| Nop10 | -7622 | 2474 | -2144 | 6281 | -3956 |
| Nop14 | 3186 | 6039 | -2470 | -673 | -5975 |
| Nop2 | -5966 | 4336 | -4966 | -4569 | -3564 |
| Nop56 | -6236 | -2946 | -1521 | 4690 | -924 |
| Nop58 | 3953 | 816 | 301 | 35 | -7381 |
| Nsun4 | 4572 | -160 | 3568 | 265 | 7197 |
| Pdcd11 | -4668 | -6931 | 1484 | 1144 | -3025 |
| Pelp1 | 613 | 1295 | 5640 | 999 | -3071 |
| Pes1 | 5773 | 3817 | 4130 | 6027 | 2925 |
| Pno1 | -3813 | 4096 | 1057 | 5874 | 2146 |
| Prorp | -4573 | 2206 | 6244 | 994 | 6256 |
| Pwp2 | -5734 | -3735 | 3192 | -2574 | -716 |
| Rbm28 | -1288 | -3441 | -1306 | -5207 | -2290 |
| Rcl1 | -3247 | 1705 | 2035 | 5749 | 2272 |
| Riok1 | 6591 | -3846 | 3023 | 1270 | -18 |
| Riok2 | -4183 | -1482 | 4514 | 1782 | 5935 |
| Riok3 | 6010 | -1592 | 3191 | 2328 | 4820 |
| Rpl10 | 7552 | 2305 | -6483 | 1980 | 1798 |
| Rpl10a | -4754 | 5887 | -3904 | 6315 | -6264 |
| Rpl11 | -7040 | -1610 | -1752 | 7106 | -5100 |
| Rpl12 | -1293 | 111 | -1276 | 5593 | -4815 |
| Rpl13 | -5435 | 705 | -309 | 7111 | -4751 |
| Rpl13a | -6127 | -800 | -4926 | 6137 | -3678 |
| Rpl14 | -4973 | 3377 | -3827 | 6231 | -6184 |
| Rpl15 | -1081 | 4664 | -97 | 5670 | -5225 |
| Rpl17 | -6154 | 1812 | -4356 | 5972 | -3587 |
| Rpl18 | -3623 | 1407 | 1250 | 6814 | -5632 |
| Rpl18a | -1090 | 3984 | -5189 | 6777 | -4423 |
| Rpl19 | -6145 | 1844 | 1393 | 7139 | -5256 |
| Rpl21 | -5242 | 1494 | -2632 | 6613 | -7105 |
| Rpl22 | 2309 | 1493 | 135 | 7361 | -5393 |
| Rpl22l1 | -6274 | -4977 | -2367 | 6270 | -5683 |
| Rpl23 | -4886 | -1314 | -5284 | 6983 | -7403 |
| Rpl23a | -5685 | 181 | -4668 | 5986 | -6814 |
| Rpl24 | -6576 | 1391 | -3886 | 6934 | -6380 |
| Rpl26 | -6659 | 1690 | -587 | 7025 | -6436 |
| Rpl27 | -6845 | 1737 | -3419 | 6972 | -3911 |
| Rpl27a | -5517 | 3660 | -2513 | 5849 | -4735 |
| Rpl28 | -1279 | 5641 | -1248 | 5705 | -5460 |
| Rpl29 | -1125 | 4140 | -4187 | 6593 | -5922 |
| Rpl3 | -4393 | 97 | 1158 | 6008 | -4443 |
| Rpl30 | -3489 | -1769 | -4305 | 6489 | -7269 |
| Rpl31 | -6836 | -3203 | -1412 | 7055 | -6596 |
| Rpl32 | -4734 | -2231 | 1048 | 7325 | -5634 |
| Rpl34 | -5472 | -4039 | -1304 | 7052 | -5665 |
| Rpl35 | -5746 | -5044 | -3769 | 7203 | -6944 |
| Rpl35a | -5482 | -3840 | 570 | 7450 | -6779 |
| Rpl36 | -4150 | -526 | -925 | 7394 | -6244 |
| Rpl36a | -5737 | 966 | -3217 | 6846 | -6933 |
| Rpl36al | -5513 | 1911 | -471 | 7142 | -7041 |
| Rpl37 | -4803 | -2009 | -157 | 7169 | -7308 |
| Rpl37a | -5196 | -2693 | 70 | 7353 | -7233 |
| Rpl38 | -4285 | -3890 | 857 | 7427 | -7458 |
| Rpl39 | -6226 | -2451 | 1477 | 7435 | -7398 |
| Rpl4 | -4925 | 1852 | -4074 | 6135 | -4712 |
| Rpl5 | 5744 | -2476 | -3141 | 5665 | 42 |
| Rpl6 | -5411 | 5527 | -1164 | 5021 | -4217 |
| Rpl7 | -5113 | 1762 | 151 | 6242 | -4040 |
| Rpl7a | -3564 | 4076 | 1931 | 6938 | -2667 |
| Rpl8 | -3703 | 3543 | -3664 | 6481 | -4491 |
| Rpl9 | -5504 | 344 | 903 | 6756 | -2526 |
| Rplp0 | -3763 | 4412 | -942 | 6357 | 956 |
| Rplp1 | -3659 | -3603 | -814 | 6990 | -6512 |
| Rplp2 | -1405 | 721 | 5081 | 7200 | -5799 |
| Rpp14 | -7709 | -32 | -3262 | 2652 | 3658 |
| Rpp21 | -3012 | 2025 | 6220 | 5886 | -6379 |
| Rpp25 | 5272 | 4802 | 6352 | 6637 | -3213 |
| Rpp30 | -3138 | 4151 | -4983 | 2569 | -1250 |
| Rpp38 | -6179 | -4212 | -858 | 4196 | -4504 |
| Rpp40 | 720 | -779 | -2883 | 3767 | -3076 |
| Rps10 | -5436 | 1596 | -1596 | 7118 | -2524 |
| Rps11 | -6088 | -966 | -1330 | 6240 | -6425 |
| Rps12 | -6536 | 2445 | -4827 | 7047 | -5574 |
| Rps13 | -2674 | -235 | -1978 | 6430 | -3919 |
| Rps14 | -3675 | 1734 | 3410 | 7146 | -3493 |
| Rps15 | -5634 | 2477 | 239 | 7130 | -5513 |
| Rps15a | 369 | 608 | -3369 | 6779 | -5204 |
| Rps16 | -4792 | 2799 | -1537 | 6267 | -5455 |
| Rps17 | -5260 | -1557 | 1246 | 7182 | -6746 |
| Rps18 | -4838 | 1158 | 194 | 6830 | -4753 |
| Rps19 | -6105 | -2857 | -5576 | 6611 | -5782 |
| Rps2 | -2017 | 387 | -812 | 6266 | -3726 |
| Rps20 | -4819 | -1197 | -4402 | 5625 | -7090 |
| Rps21 | -4549 | -3950 | -722 | 7488 | -7191 |
| Rps23 | -6959 | 2961 | -3533 | 6890 | -7067 |
| Rps24 | -6377 | -301 | -5394 | 5997 | -5015 |
| Rps25 | -6573 | -1150 | -1883 | 6238 | -5538 |
| Rps26 | -5325 | 3572 | -3697 | 5769 | -6007 |
| Rps27 | -5449 | -2098 | 2068 | 7449 | -7364 |
| Rps27a | -6372 | -7132 | -2043 | 6853 | -6401 |
| Rps27l | -4990 | -3246 | -4325 | 6048 | -3758 |
| Rps28 | -2854 | -2799 | 2837 | 7397 | -7470 |
| Rps29 | -234 | -4717 | -446 | 7482 | -7465 |
| Rps3 | -5535 | 1738 | -2705 | 6117 | -1500 |
| Rps3a1 | -6001 | 295 | -2164 | 5731 | -4251 |
| Rps4x | -3555 | -300 | -4680 | 5409 | -4453 |
| Rps5 | -4284 | 1344 | -1916 | 5993 | -4583 |
| Rps6 | -4272 | 4707 | 1599 | 6014 | -5295 |
| Rps7 | -5696 | 1849 | -3387 | 6808 | -5804 |
| Rps8 | -6704 | -566 | -5243 | 7004 | -6741 |
| Rps9 | -5004 | 1757 | -844 | 6794 | -4576 |
| Rpsa | -5034 | -2245 | -4844 | 5145 | -2970 |
| Rrp1 | -3910 | 2645 | 4697 | 4743 | -6070 |
| Rrp36 | -7983 | -1185 | -3670 | 7049 | -637 |
| Rrp7a | -4480 | -2447 | 354 | 3344 | -2507 |
| Rrp9 | -7661 | -2345 | 1812 | 3545 | -2992 |
| Senp3 | 1531 | 436 | 733 | 544 | 4006 |
| Snu13 | -5832 | 716 | -529 | 6149 | 180 |
| Tbl3 | 4625 | 1978 | 7571 | 4316 | 8173 |
| Tex10 | 5310 | -7707 | -7792 | -2884 | -6681 |
| Tfb1m | -1292 | 2810 | 4843 | -240 | -6059 |
| Thumpd1 | 5996 | 3691 | 5765 | 3992 | 3857 |
| Trmt10c | 661 | -63 | 3517 | 3419 | 2120 |
| Trmt112 | -2542 | 6716 | -5903 | 5218 | -6826 |
| Tsr1 | 7396 | 342 | 2689 | -113 | 6708 |
| Tsr3 | -4365 | 144 | 1402 | 6775 | 906 |
| Uba52 | -2504 | 5042 | 585 | 6605 | -5655 |
| Utp11 | -8076 | 2036 | -6772 | 2935 | -4409 |
| Utp14a | 3014 | 2003 | -5246 | -1434 | -3086 |
| Utp15 | 1888 | -4341 | -3103 | -5808 | -1428 |
| Utp18 | -871 | 2960 | -1270 | -1026 | -2520 |
| Utp20 | 1410 | 8 | 6331 | -7145 | 841 |
| Utp25 | 7655 | 4715 | -4041 | 1704 | 2593 |
| Utp3 | -6029 | -5208 | -1932 | 4749 | -7434 |
| Utp4 | 938 | -56 | -3453 | -6067 | 3587 |
| Utp6 | -6502 | -2482 | -6822 | -3163 | 4455 |
| Wdr12 | -7705 | 4 | -2688 | -745 | -988 |
| Wdr18 | -3116 | 1929 | 3849 | 6766 | 4692 |
| Wdr3 | -6829 | 691 | 7286 | -8019 | 4395 |
| Wdr36 | -3917 | 4002 | -1976 | -615 | -279 |
| Wdr43 | -7417 | 5907 | 3174 | 1794 | 4465 |
| Wdr46 | 1737 | -1683 | 5043 | 4374 | 2551 |
| Wdr75 | -6168 | -1662 | -5453 | -3903 | -1018 |
| Xrn2 | 6705 | 5960 | -21 | 7311 | 7224 |
BIOTIN TRANSPORT AND METABOLISM
| metric | value |
|---|---|
| setSize | 11 |
| pMANOVA | 0.00731 |
| p.adjustMANOVA | 0.0226 |
| s.dist | 0.73 |
| s.hyp | 0.111 |
| s.hip | 0.55 |
| s.amy | 0.338 |
| s.pag | -0.00956 |
| s.ni | 0.323 |
| p.hyp | 0.524 |
| p.hip | 0.00157 |
| p.amy | 0.0525 |
| p.pag | 0.956 |
| p.ni | 0.064 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | hip | amy |
|---|---|---|
| Pccb | 6774 | 7335 |
| Hlcs | 6687 | 6690 |
| Mccc2 | 7056 | 3324 |
| Acacb | 6228 | 2952 |
| Btd | 4575 | 3637 |
| Pdzd11 | 1505 | 6079 |
| Pcx | 5280 | 496 |
| Mccc1 | 1579 | 1173 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Acaca | -127 | -5798 | -842 | -7383 | 1886 |
| Acacb | 6376 | 6228 | 2952 | -4760 | 8286 |
| Btd | -7199 | 4575 | 3637 | -2445 | 289 |
| Hlcs | 6930 | 6687 | 6690 | -63 | 6000 |
| Mccc1 | 2041 | 1579 | 1173 | -5482 | 3035 |
| Mccc2 | 7172 | 7056 | 3324 | 3356 | -3100 |
| Pcca | -1767 | 2233 | -562 | 7527 | 6754 |
| Pccb | -3903 | 6774 | 7335 | 6081 | -1278 |
| Pcx | -2192 | 5280 | 496 | -2092 | 7847 |
| Pdzd11 | -65 | 1505 | 6079 | 4903 | -114 |
| Slc5a6 | 462 | 5338 | -585 | -5162 | 4146 |
CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE
| metric | value |
|---|---|
| setSize | 11 |
| pMANOVA | 0.0113 |
| p.adjustMANOVA | 0.0321 |
| s.dist | 0.724 |
| s.hyp | -0.319 |
| s.hip | -0.405 |
| s.amy | -0.151 |
| s.pag | -0.466 |
| s.ni | 0.136 |
| p.hyp | 0.0672 |
| p.hip | 0.0202 |
| p.amy | 0.387 |
| p.pag | 0.0074 |
| p.ni | 0.434 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | hip |
|---|---|---|
| Creb1 | -8066 | -8363 |
| Prkacb | -6658 | -5615 |
| Prkar2a | -8197 | -4370 |
| Prkx | -7019 | -4528 |
| Prkar2b | -3385 | -5589 |
| Prkar1b | -1693 | -3433 |
| Prkar1a | -2814 | -1823 |
| Adcy1 | -569 | -5883 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Adcy1 | 6550 | -5883 | 1481 | -569 | 7791 |
| Adcy8 | -7137 | 349 | -3569 | -6760 | -2592 |
| Calm1 | -3210 | -5777 | -2383 | 480 | 4856 |
| Creb1 | -6520 | -8363 | -6284 | -8066 | 984 |
| Prkaca | 536 | 2584 | 4026 | -974 | -911 |
| Prkacb | -5780 | -5615 | -705 | -6658 | 2764 |
| Prkar1a | -1344 | -1823 | 1101 | -2814 | 7059 |
| Prkar1b | -1456 | -3433 | 5947 | -1693 | 4760 |
| Prkar2a | -6880 | -4370 | -4761 | -8197 | 4398 |
| Prkar2b | -3250 | -5589 | -1825 | -3385 | -6274 |
| Prkx | -1534 | -4528 | -6228 | -7019 | -5454 |
NEGATIVE REGULATION OF NOTCH4 SIGNALING
| metric | value |
|---|---|
| setSize | 54 |
| pMANOVA | 4.6e-16 |
| p.adjustMANOVA | 1.89e-14 |
| s.dist | 0.724 |
| s.hyp | -0.382 |
| s.hip | 0.05 |
| s.amy | 0.0849 |
| s.pag | 0.582 |
| s.ni | -0.17 |
| p.hyp | 1.18e-06 |
| p.hip | 0.525 |
| p.amy | 0.281 |
| p.pag | 1.31e-13 |
| p.ni | 0.0305 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | hyp |
|---|---|---|
| Psma4 | 6831 | -7504 |
| Psmb3 | 7151 | -6332 |
| Rps27a | 6853 | -6372 |
| Psma3 | 7155 | -6066 |
| Psma7 | 6865 | -6285 |
| Sem1 | 6969 | -6006 |
| Psmb6 | 6933 | -5672 |
| Psma6 | 6511 | -5994 |
| Tacc3 | 5725 | -6674 |
| Psma1 | 4832 | -7420 |
| Psma2 | 6209 | -5644 |
| Psmc2 | 5333 | -6518 |
| Psmb1 | 5823 | -5858 |
| Psmd14 | 5163 | -6510 |
| Skp1 | 4373 | -7030 |
| Psme1 | 6188 | -4847 |
| Psmb4 | 6715 | -4320 |
| Ubb | 6541 | -4378 |
| Psme2 | 4745 | -5948 |
| Psmb5 | 7354 | -3602 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Akt1 | -725 | 267 | 1944 | 3433 | 7591 |
| Cul1 | 5439 | 4556 | -3455 | -2303 | 3314 |
| Fbxw7 | -474 | -7149 | 4798 | -790 | 3165 |
| Notch4 | 7638 | 3639 | 6478 | 5522 | 7513 |
| Psma1 | -7420 | -4010 | -2108 | 4832 | 1858 |
| Psma2 | -5644 | 3865 | -2900 | 6209 | 1865 |
| Psma3 | -6066 | 979 | -2046 | 7155 | -4041 |
| Psma4 | -7504 | 977 | 368 | 6831 | -5642 |
| Psma5 | -2124 | -1232 | 2483 | 4725 | 2300 |
| Psma6 | -5994 | 3421 | -370 | 6511 | 835 |
| Psma7 | -6285 | 2069 | 2339 | 6865 | 571 |
| Psmb1 | -5858 | -1406 | -2701 | 5823 | -2062 |
| Psmb10 | -3492 | 4071 | 526 | 5974 | -4727 |
| Psmb2 | -634 | 4648 | 5325 | 7007 | 830 |
| Psmb3 | -6332 | -4121 | 2181 | 7151 | -84 |
| Psmb4 | -4320 | 1432 | -1045 | 6715 | -3833 |
| Psmb5 | -3602 | 1198 | 3279 | 7354 | -522 |
| Psmb6 | -5672 | -1356 | -959 | 6933 | -4272 |
| Psmb7 | -1170 | 1445 | 2791 | 7138 | -1108 |
| Psmb8 | -4080 | -6385 | -7753 | 1678 | -7164 |
| Psmb9 | -4395 | 2842 | -6017 | -1361 | -6203 |
| Psmc1 | -3306 | -2805 | 3510 | 5660 | -2811 |
| Psmc2 | -6518 | 3638 | 311 | 5333 | 14 |
| Psmc3 | -2810 | -6533 | 330 | 5063 | -1709 |
| Psmc4 | -1805 | -523 | 3727 | 6567 | -1984 |
| Psmc5 | -3339 | 1551 | -4032 | 5126 | -3280 |
| Psmc6 | -6889 | -1882 | -5077 | 3383 | 2777 |
| Psmd1 | -6211 | -4112 | 2043 | 1517 | 1743 |
| Psmd10 | -5057 | 5662 | -811 | 3277 | 1494 |
| Psmd11 | -3954 | -7414 | -6745 | -3634 | -2989 |
| Psmd12 | -7136 | -641 | -4440 | 3580 | -1003 |
| Psmd13 | -420 | 3420 | 1880 | 6754 | -3079 |
| Psmd14 | -6510 | -4665 | 1516 | 5163 | 1500 |
| Psmd2 | 5901 | -1504 | 6553 | -254 | 4336 |
| Psmd3 | 6 | -1368 | 4418 | 6572 | -1820 |
| Psmd4 | -3476 | -556 | 3530 | 4997 | -899 |
| Psmd5 | -7412 | -4455 | -6171 | -4153 | 7500 |
| Psmd6 | -5055 | -1678 | -1384 | 2086 | 1811 |
| Psmd7 | 88 | -5762 | 6557 | 6395 | -2888 |
| Psmd8 | -1002 | 758 | 5775 | 5963 | -933 |
| Psmd9 | -869 | -4765 | -1399 | 6885 | -2353 |
| Psme1 | -4847 | 4903 | 2140 | 6188 | -6113 |
| Psme2 | -5948 | -131 | -860 | 4745 | -6182 |
| Psme3 | 2209 | -3777 | 5865 | -3604 | 6598 |
| Psmf1 | 2377 | 3789 | 7161 | 2699 | 6535 |
| Rbx1 | 234 | -1186 | -2007 | 6309 | -3980 |
| Rps27a | -6372 | -7132 | -2043 | 6853 | -6401 |
| Sem1 | -6006 | 529 | -1985 | 6969 | -6676 |
| Skp1 | -7030 | -655 | -398 | 4373 | 1142 |
| Tacc3 | -6674 | 4929 | 6296 | 5725 | -2186 |
| Uba52 | -2504 | 5042 | 585 | 6605 | -5655 |
| Ubb | -4378 | 3667 | 1287 | 6541 | -5290 |
| Ubc | -1247 | 3415 | 2683 | -2012 | -1479 |
| Ywhaz | 336 | -1873 | 4676 | -3566 | -2575 |
PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING
| metric | value |
|---|---|
| setSize | 11 |
| pMANOVA | 0.00916 |
| p.adjustMANOVA | 0.0275 |
| s.dist | 0.721 |
| s.hyp | 0.395 |
| s.hip | -0.232 |
| s.amy | 0.402 |
| s.pag | -0.386 |
| s.ni | 0.0224 |
| p.hyp | 0.0234 |
| p.hip | 0.183 |
| p.amy | 0.0211 |
| p.pag | 0.0267 |
| p.ni | 0.898 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | amy | hyp |
|---|---|---|
| Cacna1e | 6936 | 6197 |
| Cacnb3 | 6511 | 6311 |
| Cacna1b | 7298 | 4997 |
| Cacna2d3 | 4129 | 5831 |
| Cacna1a | 5610 | 3802 |
| Cacnb1 | 6234 | 1524 |
| Cacnb2 | 1406 | 4802 |
| Cacna2d2 | 1192 | 4313 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Cacna1a | 3802 | -5311 | 5610 | -3347 | 3475 |
| Cacna1b | 4997 | -1552 | 7298 | -6236 | 440 |
| Cacna1e | 6197 | -7845 | 6936 | -7992 | -3711 |
| Cacna2d2 | 4313 | 4362 | 1192 | -2579 | 2557 |
| Cacna2d3 | 5831 | 744 | 4129 | -3448 | 7281 |
| Cacnb1 | 1524 | -8297 | 6234 | -7272 | -1478 |
| Cacnb2 | 4802 | 234 | 1406 | -5481 | 3692 |
| Cacnb3 | 6311 | -7576 | 6511 | -5054 | -2668 |
| Cacnb4 | 4051 | -5803 | -438 | -3739 | 7573 |
| Cacng2 | -4441 | 1887 | -3216 | 3644 | -2985 |
| Cacng4 | -4738 | 1861 | -353 | 2914 | -6794 |
COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING
| metric | value |
|---|---|
| setSize | 26 |
| pMANOVA | 1.69e-06 |
| p.adjustMANOVA | 1.53e-05 |
| s.dist | 0.719 |
| s.hyp | -0.488 |
| s.hip | -0.134 |
| s.amy | -0.0583 |
| s.pag | 0.37 |
| s.ni | -0.348 |
| p.hyp | 1.65e-05 |
| p.hip | 0.237 |
| p.amy | 0.607 |
| p.pag | 0.0011 |
| p.ni | 0.00211 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | hyp | pag |
|---|---|---|
| Pfdn5 | -5586 | 6325 |
| Pfdn1 | -4880 | 6680 |
| Pfdn6 | -4423 | 7177 |
| Cct5 | -7287 | 3825 |
| Pfdn2 | -3890 | 5967 |
| Cct3 | -7734 | 2831 |
| Tuba1a | -5422 | 3572 |
| Cct2 | -6976 | 2670 |
| Tubb4b | -5695 | 3097 |
| Pfdn4 | -7842 | 2216 |
| Cct7 | -7381 | 2117 |
| Vbp1 | -7942 | 1328 |
| Tubb3 | -2697 | 3566 |
| Tubb2a | -4425 | 1810 |
| Tcp1 | -6241 | 1082 |
| Tubb4a | -1886 | 3342 |
| Tuba1b | -3026 | 1706 |
| Cct8 | -4413 | 648 |
| Tuba4a | -464 | 2676 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Actb | 172 | -2786 | 6540 | 1236 | -4618 |
| Cct2 | -6976 | -6216 | -4431 | 2670 | -2928 |
| Cct3 | -7734 | -7399 | -1737 | 2831 | -4158 |
| Cct4 | -7846 | -7519 | -6415 | -2536 | -6802 |
| Cct5 | -7287 | -3378 | -1743 | 3825 | -3457 |
| Cct6a | -7949 | -4985 | -4197 | -717 | -3098 |
| Cct7 | -7381 | -8123 | -2899 | 2117 | -5938 |
| Cct8 | -4413 | -6328 | -4084 | 648 | -4316 |
| Pfdn1 | -4880 | 2985 | -1140 | 6680 | -4865 |
| Pfdn2 | -3890 | 2147 | -325 | 5967 | -7085 |
| Pfdn4 | -7842 | -1286 | -1495 | 2216 | -5421 |
| Pfdn5 | -5586 | -592 | -3078 | 6325 | -4013 |
| Pfdn6 | -4423 | 3532 | 883 | 7177 | -5876 |
| Tcp1 | -6241 | -6345 | -3761 | 1082 | -4000 |
| Tuba1a | -5422 | -8 | 3860 | 3572 | -1571 |
| Tuba1b | -3026 | -1501 | -2474 | 1706 | 1084 |
| Tuba1c | 7751 | 4601 | -4435 | 1956 | 3635 |
| Tuba4a | -464 | -6482 | 6752 | 2676 | 4991 |
| Tuba8 | 7361 | -6707 | 7647 | 6804 | -200 |
| Tubb2a | -4425 | 6203 | 3896 | 1810 | -4403 |
| Tubb2b | -7631 | -525 | -7115 | -2860 | -5116 |
| Tubb3 | -2697 | 4372 | 2624 | 3566 | 931 |
| Tubb4a | -1886 | 3082 | 5443 | 3342 | 3352 |
| Tubb4b | -5695 | 2166 | 3550 | 3097 | 1598 |
| Tubb6 | 345 | 545 | -3085 | -885 | 352 |
| Vbp1 | -7942 | -3561 | -807 | 1328 | 2473 |
TRAF3 DEPENDENT IRF ACTIVATION PATHWAY
| metric | value |
|---|---|
| setSize | 13 |
| pMANOVA | 0.0196 |
| p.adjustMANOVA | 0.0496 |
| s.dist | 0.716 |
| s.hyp | -0.211 |
| s.hip | -0.401 |
| s.amy | -0.347 |
| s.pag | -0.433 |
| s.ni | 0.00433 |
| p.hyp | 0.189 |
| p.hip | 0.0123 |
| p.amy | 0.0304 |
| p.pag | 0.00684 |
| p.ni | 0.978 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | hip |
|---|---|---|
| Traf3 | -6833 | -7345 |
| Ddx58 | -5179 | -8007 |
| Crebbp | -5698 | -6540 |
| Sike1 | -5176 | -6022 |
| Ifih1 | -8045 | -2770 |
| Ikbke | -3261 | -4995 |
| Ep300 | -4410 | -3349 |
| Trim25 | -3104 | -4288 |
| Irf3 | -1185 | -5376 |
| Mavs | -4923 | -1071 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Crebbp | 5856 | -6540 | 2739 | -5698 | -6903 |
| Ddx58 | -4298 | -8007 | -2124 | -5179 | -3533 |
| Ep300 | 1346 | -3349 | -2137 | -4410 | 4066 |
| Ifih1 | 890 | -2770 | -7809 | -8045 | -1905 |
| Ikbke | -657 | -4995 | 4371 | -3261 | 1491 |
| Irf3 | -5768 | -5376 | -1103 | -1185 | -7110 |
| Irf7 | 1101 | -8554 | -7597 | 2262 | -3028 |
| Mavs | -3159 | -1071 | -1657 | -4923 | 6917 |
| Rnf135 | -1744 | 5488 | -4242 | -1281 | 5257 |
| Sike1 | -7550 | -6022 | -3240 | -5176 | 3017 |
| Tbk1 | -6450 | 3020 | -5564 | -3672 | 2664 |
| Traf3 | -4865 | -7345 | -5306 | -6833 | 1194 |
| Trim25 | 1053 | -4288 | -2307 | -3104 | 4725 |
ADENYLATE CYCLASE INHIBITORY PATHWAY
| metric | value |
|---|---|
| setSize | 13 |
| pMANOVA | 0.00299 |
| p.adjustMANOVA | 0.0109 |
| s.dist | 0.714 |
| s.hyp | 0.0959 |
| s.hip | -0.221 |
| s.amy | 0.02 |
| s.pag | -0.662 |
| s.ni | 0.113 |
| p.hyp | 0.549 |
| p.hip | 0.167 |
| p.amy | 0.901 |
| p.pag | 3.53e-05 |
| p.ni | 0.48 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | hip |
|---|---|---|
| Adcy4 | -8405 | -7008 |
| Adcy3 | -7195 | -8015 |
| Adcy2 | -5988 | -6343 |
| Gnai3 | -4572 | -4674 |
| Adcy6 | -8137 | -2399 |
| Gnai1 | -4433 | -3365 |
| Adcy9 | -4061 | -3268 |
| Adcy1 | -569 | -5883 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Adcy1 | 6550 | -5883 | 1481 | -569 | 7791 |
| Adcy2 | 5238 | -6343 | 5164 | -5988 | 4022 |
| Adcy3 | 2809 | -8015 | 5837 | -7195 | 2370 |
| Adcy4 | -7925 | -7008 | -6394 | -8405 | -6896 |
| Adcy5 | 5698 | 1302 | 4984 | -7109 | 2333 |
| Adcy6 | 3415 | -2399 | 428 | -8137 | -2772 |
| Adcy7 | 2896 | 1967 | -689 | -8304 | 5066 |
| Adcy8 | -7137 | 349 | -3569 | -6760 | -2592 |
| Adcy9 | 4621 | -3268 | 6495 | -4061 | 4438 |
| Gnai1 | -7586 | -3365 | -2697 | -4433 | 2266 |
| Gnai2 | -4861 | 4027 | -6734 | -2244 | -4963 |
| Gnai3 | -2266 | -4674 | -2638 | -4572 | 1506 |
| Gnal | 6117 | 2185 | 443 | -6523 | 5570 |
MITOCHONDRIAL PROTEIN IMPORT
| metric | value |
|---|---|
| setSize | 63 |
| pMANOVA | 2.86e-17 |
| p.adjustMANOVA | 1.27e-15 |
| s.dist | 0.712 |
| s.hyp | -0.239 |
| s.hip | 0.176 |
| s.amy | 0.0449 |
| s.pag | 0.643 |
| s.ni | -0.0604 |
| p.hyp | 0.00103 |
| p.hip | 0.016 |
| p.amy | 0.538 |
| p.pag | 9.77e-19 |
| p.ni | 0.407 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | pag | hyp |
|---|---|---|
| Timm8b | 7295 | -7076 |
| Fxn | 6236 | -7245 |
| Timm9 | 6366 | -6663 |
| Tomm22 | 7265 | -5795 |
| Timm23 | 7204 | -5748 |
| Cox17 | 7358 | -5578 |
| Tomm5 | 6691 | -6134 |
| Ndufb8 | 7254 | -5455 |
| Tomm6 | 7048 | -5389 |
| Pmpcb | 5047 | -7063 |
| Coa4 | 5049 | -7038 |
| Atp5g1 | 7378 | -4692 |
| Chchd4 | 6060 | -5401 |
| Grpel1 | 7306 | -4461 |
| Timm22 | 6449 | -4971 |
| Cox19 | 5991 | -5148 |
| Coa6 | 3797 | -7380 |
| Timm50 | 5671 | -4930 |
| Chchd2 | 5387 | -5001 |
| Dnajc19 | 7467 | -3357 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Aco2 | 5025 | 873 | 1479 | 2225 | 8071 |
| Atp5a1 | 85 | 172 | 1149 | 1994 | 5105 |
| Atp5b | -231 | -1196 | -507 | 6630 | 4246 |
| Atp5g1 | -4692 | -4063 | -1542 | 7378 | -921 |
| Bcs1l | -2096 | 937 | 947 | -557 | 4570 |
| Chchd10 | 659 | 6662 | 1537 | 6809 | -3518 |
| Chchd2 | -5001 | 1520 | -4065 | 5387 | -3865 |
| Chchd3 | -2013 | -2411 | 1394 | 7175 | -2172 |
| Chchd4 | -5401 | 5679 | 7167 | 6060 | -1818 |
| Chchd5 | 3509 | 2188 | -2081 | 5592 | -2479 |
| Chchd7 | -3177 | -1838 | 973 | 6069 | -3610 |
| Cmc2 | -2782 | 2466 | 4084 | 5733 | 7622 |
| Cmc4 | -5595 | 204 | 2419 | 2770 | 311 |
| Coa4 | -7038 | 5572 | -6564 | 5049 | -544 |
| Coa6 | -7380 | 6782 | -3275 | 3797 | -2016 |
| Coq2 | -3759 | -111 | 2488 | 6196 | 6134 |
| Cox17 | -5578 | -1377 | 1031 | 7358 | -7400 |
| Cox19 | -5148 | -5349 | 3732 | 5991 | 873 |
| Cs | -997 | -1921 | -2172 | 623 | 5854 |
| Cyc1 | -2233 | 4850 | 3117 | 7172 | 3586 |
| Dnajc19 | -3357 | 5835 | -2942 | 7467 | -7297 |
| Fxn | -7245 | 3296 | -7061 | 6236 | -4353 |
| Gfer | -3757 | 6771 | 2354 | 4728 | -4652 |
| Grpel1 | -4461 | 187 | 1438 | 7306 | 3492 |
| Grpel2 | -1158 | -7485 | 3965 | 4836 | 620 |
| Hscb | -1232 | -1359 | 412 | 5971 | 3881 |
| Hspa9 | -1762 | 1791 | -3119 | -402 | 2721 |
| Hspd1 | -7939 | -8179 | -7333 | -6342 | -5599 |
| Idh3g | 3672 | 6087 | 2279 | 6426 | 6570 |
| Ldhd | 4055 | 1559 | 626 | 5285 | 1357 |
| Mtx1 | 2550 | 1923 | 6338 | 6889 | -1599 |
| Mtx2 | -179 | -787 | 2691 | 5561 | -181 |
| Ndufb8 | -5455 | 591 | 1725 | 7254 | -333 |
| Pam16 | 3935 | -7652 | -7876 | 7292 | -7472 |
| Pitrm1 | -3101 | 4324 | 21 | -6646 | 7841 |
| Pmpca | 6660 | 5070 | 199 | 5571 | 5414 |
| Pmpcb | -7063 | 5016 | -2464 | 5047 | -1924 |
| Samm50 | -638 | -7884 | 1078 | -1768 | -1324 |
| Slc25a12 | 1244 | 4301 | 5027 | -5680 | 6399 |
| Slc25a13 | 5129 | 7350 | 3152 | 5968 | 8426 |
| Slc25a4 | -2495 | 4740 | -2447 | 5750 | 363 |
| Taz | 2149 | 117 | 6741 | 1412 | -4846 |
| Timm10 | -2174 | 5363 | -362 | 7076 | 1039 |
| Timm10b | 1550 | -242 | -3363 | 6921 | -1604 |
| Timm13 | -2116 | 3624 | 2151 | 7474 | -5514 |
| Timm17a | -197 | -3170 | -7267 | 5005 | -589 |
| Timm17b | -6430 | 2395 | -2057 | 3869 | 383 |
| Timm21 | 1061 | 4720 | 2071 | 6186 | -4474 |
| Timm22 | -4971 | 487 | 411 | 6449 | 3493 |
| Timm23 | -5748 | -557 | 1106 | 7204 | 3920 |
| Timm44 | -4644 | -1316 | -940 | 5156 | -2643 |
| Timm50 | -4930 | -445 | -774 | 5671 | -3720 |
| Timm8a1 | -1869 | -3161 | 753 | 6173 | 367 |
| Timm8b | -7076 | -1727 | -1707 | 7295 | -4600 |
| Timm9 | -6663 | -44 | 2115 | 6366 | -5061 |
| Tomm20 | -1494 | -1498 | 3523 | 187 | 4954 |
| Tomm22 | -5795 | -3247 | -938 | 7265 | -2785 |
| Tomm40 | 1394 | 3778 | 5466 | 6050 | 973 |
| Tomm5 | -6134 | -3748 | 3388 | 6691 | -2848 |
| Tomm6 | -5389 | -1013 | -4449 | 7048 | -4670 |
| Tomm7 | -2648 | -890 | 954 | 7537 | -6432 |
| Tomm70a | 2500 | 2431 | -12 | -1935 | 6947 |
| Vdac1 | 4541 | 1517 | 6512 | 4559 | -1925 |
MUCOPOLYSACCHARIDOSES
| metric | value |
|---|---|
| setSize | 11 |
| pMANOVA | 0.00618 |
| p.adjustMANOVA | 0.0195 |
| s.dist | 0.711 |
| s.hyp | 0.236 |
| s.hip | 0.428 |
| s.amy | 0.438 |
| s.pag | -0.192 |
| s.ni | 0.192 |
| p.hyp | 0.175 |
| p.hip | 0.0139 |
| p.amy | 0.0119 |
| p.pag | 0.269 |
| p.ni | 0.27 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | amy | hip |
|---|---|---|
| Glb1 | 7075 | 6465 |
| Sgsh | 4780 | 6978 |
| Hyal1 | 4170 | 6279 |
| Arsb | 4615 | 5126 |
| Galns | 5611 | 3798 |
| Hgsnat | 5571 | 2854 |
| Naglu | 7989 | 827 |
| Gns | 1355 | 4864 |
| Gusb | 434 | 1213 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Arsb | 5009 | 5126 | 4615 | -2007 | 6732 |
| Galns | -6308 | 3798 | 5611 | 2656 | 713 |
| Glb1 | -678 | 6465 | 7075 | 120 | 3757 |
| Gns | 3320 | 4864 | 1355 | -5963 | 5608 |
| Gusb | 3413 | 1213 | 434 | 4722 | -3906 |
| Hgsnat | 4937 | 2854 | 5571 | -2587 | 6187 |
| Hyal1 | 4204 | 6279 | 4170 | -8104 | -2157 |
| Ids | -3023 | -1652 | -1291 | -6112 | 5770 |
| Idua | 1638 | -6036 | -1813 | -4453 | -5212 |
| Naglu | 3510 | 827 | 7989 | 2948 | 7785 |
| Sgsh | 2726 | 6978 | 4780 | -2805 | -2982 |
NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION
| metric | value |
|---|---|
| setSize | 21 |
| pMANOVA | 6.46e-05 |
| p.adjustMANOVA | 0.000387 |
| s.dist | 0.707 |
| s.hyp | 0.352 |
| s.hip | -0.35 |
| s.amy | 0.343 |
| s.pag | -0.243 |
| s.ni | 0.277 |
| p.hyp | 0.00526 |
| p.hip | 0.00556 |
| p.amy | 0.00654 |
| p.pag | 0.0537 |
| p.ni | 0.0281 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | hyp | hip |
|---|---|---|
| Grin2a | 7735 | -7350 |
| Grin2b | 7286 | -6440 |
| Camk4 | 6681 | -5705 |
| Dlg4 | 5080 | -6512 |
| Actn2 | 5000 | -6366 |
| Camk2a | 7207 | -4146 |
| Dlg2 | 5792 | -4706 |
| Dlg3 | 2275 | -6061 |
| Lrrc7 | 1877 | -6764 |
| Grin1 | 2829 | -3464 |
| Ppm1e | 6624 | -1276 |
| Camk2b | 7405 | -663 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Actn2 | 5000 | -6366 | 5279 | 4139 | -6863 |
| Calm1 | -3210 | -5777 | -2383 | 480 | 4856 |
| Camk1 | -7683 | -5366 | -2266 | 5537 | -6355 |
| Camk2a | 7207 | -4146 | 6629 | -5758 | 2594 |
| Camk2b | 7405 | -663 | 7585 | 1811 | -336 |
| Camk2d | 3624 | 5724 | 4117 | -6480 | 3253 |
| Camk2g | -2481 | -772 | 2753 | 2961 | 7086 |
| Camk4 | 6681 | -5705 | 4549 | -2352 | 7655 |
| Dlg1 | -2526 | -6201 | 60 | -478 | 6813 |
| Dlg2 | 5792 | -4706 | -3560 | -6197 | 5701 |
| Dlg3 | 2275 | -6061 | 7074 | -4165 | 2207 |
| Dlg4 | 5080 | -6512 | 6564 | -2292 | -5284 |
| Grin1 | 2829 | -3464 | 7216 | -4005 | 6253 |
| Grin2a | 7735 | -7350 | 4374 | -4196 | 4463 |
| Grin2b | 7286 | -6440 | 5901 | -6614 | -2727 |
| Grin2c | 7709 | 2447 | 6726 | 1345 | 8363 |
| Grin2d | -620 | 4842 | -1980 | -8301 | 495 |
| Lrrc7 | 1877 | -6764 | 2148 | -6931 | 997 |
| Nefl | -153 | -1355 | -5259 | 568 | 7113 |
| Ppm1e | 6624 | -1276 | 1601 | -4038 | 6088 |
| Ppm1f | -5340 | -5857 | 390 | -4729 | 4386 |
ATF6 ATF6 ALPHA ACTIVATES CHAPERONES
| metric | value |
|---|---|
| setSize | 12 |
| pMANOVA | 0.047 |
| p.adjustMANOVA | 0.0994 |
| s.dist | 0.704 |
| s.hyp | -0.333 |
| s.hip | -0.404 |
| s.amy | -0.388 |
| s.pag | -0.137 |
| s.ni | -0.227 |
| p.hyp | 0.0458 |
| p.hip | 0.0154 |
| p.amy | 0.0199 |
| p.pag | 0.411 |
| p.ni | 0.173 |
Warning in xtfrm.data.frame(x): cannot xtfrm data frames
| Gene | hip | amy |
|---|---|---|
| Hspa5 | -8614 | -7975 |
| Xbp1 | -8605 | -7945 |
| Hsp90b1 | -8424 | -7893 |
| Calr | -8556 | -7756 |
| Ddit3 | -8557 | -6904 |
| Nfya | -6390 | -7828 |
| Atf4 | -7556 | -3593 |
Click HERE to show all gene set members
| hyp | hip | amy | pag | ni | |
|---|---|---|---|---|---|
| Atf4 | -5109 | -7556 | -3593 | 7029 | -2762 |
| Atf6 | 7586 | -2375 | 5449 | -3372 | 8083 |
| Calr | -7354 | -8556 | -7756 | -5638 | -7238 |
| Ddit3 | -8087 | -8557 | -6904 | 5070 | -7401 |
| Hsp90b1 | -7732 | -8424 | -7893 | -4419 | -7388 |
| Hspa5 | -8142 | -8614 | -7975 | -8202 | -7402 |
| Mbtps1 | 7525 | 7285 | 6541 | -523 | 5308 |
| Mbtps2 | 1436 | 5622 | -3583 | 152 | 6970 |
| Nfya | -1638 | -6390 | -7828 | -4497 | 891 |
| Nfyb | -6572 | -3590 | 4348 | 455 | -2550 |
| Nfyc | 1976 | 3520 | -45 | 3546 | 4908 |
| Xbp1 | -7999 | -8605 | -7945 | -7851 | -7288 |
Here is the session info with all the versions of packages used.
sessionInfo()## R version 4.2.1 (2022-06-23)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.1 LTS
##
## Matrix products: default
## BLAS: /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so
##
## locale:
## [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
## [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8
## [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
## [7] LC_PAPER=en_US.UTF-8 LC_NAME=C
## [9] LC_ADDRESS=C LC_TELEPHONE=C
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
##
## attached base packages:
## [1] stats4 stats graphics grDevices utils datasets methods
## [8] base
##
## other attached packages:
## [1] pkgload_1.3.0 GGally_2.1.2
## [3] gtools_3.9.3 echarts4r_0.4.4
## [5] beeswarm_0.4.0 vioplot_0.3.7
## [7] sm_2.2-5.7.1 kableExtra_1.3.4
## [9] topconfects_1.12.0 limma_3.52.4
## [11] eulerr_6.1.1 mitch_1.8.0
## [13] MASS_7.3-58.1 fgsea_1.22.0
## [15] gplots_3.1.3 DESeq2_1.36.0
## [17] SummarizedExperiment_1.26.1 Biobase_2.56.0
## [19] MatrixGenerics_1.8.1 matrixStats_0.62.0
## [21] GenomicRanges_1.48.0 GenomeInfoDb_1.32.4
## [23] IRanges_2.30.1 S4Vectors_0.34.0
## [25] BiocGenerics_0.42.0 reshape2_1.4.4
## [27] forcats_0.5.2 stringr_1.4.1
## [29] dplyr_1.0.10 purrr_0.3.5
## [31] readr_2.1.3 tidyr_1.2.1
## [33] tibble_3.1.8 ggplot2_3.3.6
## [35] tidyverse_1.3.2 zoo_1.8-11
##
## loaded via a namespace (and not attached):
## [1] readxl_1.4.1 backports_1.4.1 fastmatch_1.1-3
## [4] systemfonts_1.0.4 plyr_1.8.7 splines_4.2.1
## [7] BiocParallel_1.30.3 digest_0.6.29 htmltools_0.5.3
## [10] fansi_1.0.3 magrittr_2.0.3 memoise_2.0.1
## [13] googlesheets4_1.0.1 tzdb_0.3.0 Biostrings_2.64.1
## [16] annotate_1.74.0 modelr_0.1.9 svglite_2.1.0
## [19] prettyunits_1.1.1 colorspace_2.0-3 blob_1.2.3
## [22] rvest_1.0.3 haven_2.5.1 xfun_0.33
## [25] crayon_1.5.2 RCurl_1.98-1.9 jsonlite_1.8.2
## [28] genefilter_1.78.0 survival_3.4-0 glue_1.6.2
## [31] gtable_0.3.1 gargle_1.2.1 zlibbioc_1.42.0
## [34] XVector_0.36.0 webshot_0.5.4 DelayedArray_0.22.0
## [37] scales_1.2.1 DBI_1.1.3 Rcpp_1.0.9
## [40] viridisLite_0.4.1 xtable_1.8-4 progress_1.2.2
## [43] bit_4.0.4 htmlwidgets_1.5.4 httr_1.4.4
## [46] RColorBrewer_1.1-3 ellipsis_0.3.2 pkgconfig_2.0.3
## [49] reshape_0.8.9 XML_3.99-0.11 farver_2.1.1
## [52] sass_0.4.2 dbplyr_2.2.1 locfit_1.5-9.6
## [55] utf8_1.2.2 tidyselect_1.2.0 labeling_0.4.2
## [58] rlang_1.0.6 later_1.3.0 AnnotationDbi_1.58.0
## [61] munsell_0.5.0 cellranger_1.1.0 tools_4.2.1
## [64] cachem_1.0.6 cli_3.4.1 generics_0.1.3
## [67] RSQLite_2.2.18 broom_1.0.1 evaluate_0.17
## [70] fastmap_1.1.0 yaml_2.3.5 knitr_1.40
## [73] bit64_4.0.5 fs_1.5.2 caTools_1.18.2
## [76] KEGGREST_1.36.3 mime_0.12 xml2_1.3.3
## [79] compiler_4.2.1 rstudioapi_0.14 png_0.1-7
## [82] reprex_2.0.2 geneplotter_1.74.0 bslib_0.4.0
## [85] stringi_1.7.8 highr_0.9 lattice_0.20-45
## [88] Matrix_1.5-1 vctrs_0.4.2 pillar_1.8.1
## [91] lifecycle_1.0.3 jquerylib_0.1.4 data.table_1.14.2
## [94] bitops_1.0-7 httpuv_1.6.6 R6_2.5.1
## [97] promises_1.2.0.1 KernSmooth_2.23-20 gridExtra_2.3
## [100] codetools_0.2-18 assertthat_0.2.1 withr_2.5.0
## [103] GenomeInfoDbData_1.2.8 parallel_4.2.1 hms_1.1.2
## [106] grid_4.2.1 rmarkdown_2.17 googledrive_2.0.0
## [109] shiny_1.7.2 lubridate_1.8.0END of report