Mitch Report

date generated: 2025-01-14

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch

	stat
5_8S_rRNA	1.8503649
A4GALT	-1.8915624
AAAS	2.1906313
AACS	1.1170591
AADAC	0.7635603
AADAT	-0.2696192

Here are some metrics about the input data profile:

Profiling data metrics

	Profile metrics
num_genesets	5133
num_genes_in_profile	14530
duplicated_genes_present	0
num_profile_genes_in_sets	9219
num_profile_genes_not_in_sets	5311

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets:

Gene set metrics

	Gene sets metrics
num_genesets	5133
num_genesets_excluded	3358
num_genesets_included	1775

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

set	setSize	pANOVA	s.dist	p.adjustANOVA
GO:0022625 cytosolic large ribosomal subunit	40	2.69e-12	-0.639	2.39e-09
GO:0031663 lipopolysaccharide-mediated signaling pathway	10	1.31e-03	-0.587	6.04e-02
GO:0009378 four-way junction helicase activity	13	2.71e-04	0.583	2.67e-02
GO:0006695 cholesterol biosynthetic process	16	5.86e-05	0.580	7.43e-03
GO:0035145 exon-exon junction complex	10	1.95e-03	0.566	7.07e-02
GO:0070182 DNA polymerase binding	13	4.89e-04	0.558	3.20e-02
GO:0061749 forked DNA-dependent helicase activity	10	2.50e-03	0.552	7.78e-02
GO:0000793 condensed chromosome	13	9.54e-04	0.529	4.70e-02
GO:0070034 telomerase RNA binding	12	1.89e-03	0.518	6.98e-02
GO:0001965 G-protein alpha-subunit binding	10	4.70e-03	-0.516	1.07e-01
GO:0003688 DNA replication origin binding	12	2.03e-03	0.514	7.21e-02
GO:1902774 late endosome to lysosome transport	10	5.92e-03	-0.503	1.22e-01
GO:0030140 trans-Golgi network transport vesicle	11	4.02e-03	-0.501	9.68e-02
GO:0036121 double-stranded DNA helicase activity	11	4.03e-03	0.501	9.68e-02
GO:0031929 TOR signaling	13	1.89e-03	-0.498	6.98e-02
GO:0022627 cytosolic small ribosomal subunit	25	1.72e-05	-0.497	3.89e-03
GO:0003899 DNA-directed 5’-3’ RNA polymerase activity	10	7.20e-03	0.491	1.40e-01
GO:0006120 mitochondrial electron transport, NADH to ubiquinone	19	3.28e-04	-0.476	2.77e-02
GO:0006268 DNA unwinding involved in DNA replication	14	2.15e-03	0.474	7.32e-02
GO:0071806 protein transmembrane transport	12	4.79e-03	-0.470	1.08e-01
GO:0022626 cytosolic ribosome	13	3.38e-03	0.470	9.09e-02
GO:0006749 glutathione metabolic process	15	1.72e-03	-0.468	6.63e-02
GO:0034314 Arp2/3 complex-mediated actin nucleation	11	7.48e-03	-0.466	1.43e-01
GO:0006337 nucleosome disassembly	10	1.08e-02	0.466	1.67e-01
GO:0060047 heart contraction	10	1.15e-02	-0.461	1.71e-01
GO:0072583 clathrin-dependent endocytosis	19	5.43e-04	-0.458	3.21e-02
GO:0030658 transport vesicle membrane	13	4.32e-03	-0.457	1.01e-01
GO:1904646 cellular response to amyloid-beta	10	1.34e-02	-0.452	1.82e-01
GO:0046326 positive regulation of D-glucose import	14	4.21e-03	-0.442	9.95e-02
GO:0007129 homologous chromosome pairing at meiosis	13	6.37e-03	0.437	1.28e-01
GO:0045271 respiratory chain complex I	31	2.58e-05	-0.437	5.09e-03
GO:0016581 NuRD complex	10	1.71e-02	0.436	2.09e-01
GO:0033344 cholesterol efflux	12	9.10e-03	-0.435	1.52e-01
GO:1990391 DNA repair complex	10	1.76e-02	0.434	2.12e-01
GO:0030904 retromer complex	15	3.73e-03	-0.433	9.59e-02
GO:0050829 defense response to Gram-negative bacterium	11	1.30e-02	0.433	1.82e-01
GO:0035371 microtubule plus-end	12	9.88e-03	0.430	1.62e-01
GO:0070530 K63-linked polyubiquitin modification-dependent protein binding	17	2.20e-03	0.429	7.37e-02
GO:0030282 bone mineralization	23	3.71e-04	-0.429	2.97e-02
GO:0035855 megakaryocyte development	10	1.90e-02	0.429	2.17e-01
GO:0140662 ATP-dependent protein folding chaperone	23	3.85e-04	0.428	2.97e-02
GO:0030501 positive regulation of bone mineralization	13	7.76e-03	-0.427	1.43e-01
GO:0001968 fibronectin binding	10	1.97e-02	0.426	2.20e-01
GO:0006352 DNA-templated transcription initiation	11	1.49e-02	0.424	1.95e-01
GO:1990498 mitotic spindle microtubule	10	2.05e-02	0.423	2.23e-01
GO:0005158 insulin receptor binding	13	8.63e-03	-0.421	1.51e-01
GO:0010811 positive regulation of cell-substrate adhesion	13	8.77e-03	-0.420	1.51e-01
GO:0003735 structural constituent of ribosome	118	4.37e-15	-0.418	7.75e-12
GO:0005049 nuclear export signal receptor activity	10	2.27e-02	0.416	2.37e-01
GO:0007042 lysosomal lumen acidification	10	2.54e-02	-0.408	2.52e-01

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
GO:0022625 cytosolic large ribosomal subunit	40	2.69e-12	-0.639000	2.39e-09
GO:0031663 lipopolysaccharide-mediated signaling pathway	10	1.31e-03	-0.587000	6.04e-02
GO:0009378 four-way junction helicase activity	13	2.71e-04	0.583000	2.67e-02
GO:0006695 cholesterol biosynthetic process	16	5.86e-05	0.580000	7.43e-03
GO:0035145 exon-exon junction complex	10	1.95e-03	0.566000	7.07e-02
GO:0070182 DNA polymerase binding	13	4.89e-04	0.558000	3.20e-02
GO:0061749 forked DNA-dependent helicase activity	10	2.50e-03	0.552000	7.78e-02
GO:0000793 condensed chromosome	13	9.54e-04	0.529000	4.70e-02
GO:0070034 telomerase RNA binding	12	1.89e-03	0.518000	6.98e-02
GO:0001965 G-protein alpha-subunit binding	10	4.70e-03	-0.516000	1.07e-01
GO:0003688 DNA replication origin binding	12	2.03e-03	0.514000	7.21e-02
GO:1902774 late endosome to lysosome transport	10	5.92e-03	-0.503000	1.22e-01
GO:0030140 trans-Golgi network transport vesicle	11	4.02e-03	-0.501000	9.68e-02
GO:0036121 double-stranded DNA helicase activity	11	4.03e-03	0.501000	9.68e-02
GO:0031929 TOR signaling	13	1.89e-03	-0.498000	6.98e-02
GO:0022627 cytosolic small ribosomal subunit	25	1.72e-05	-0.497000	3.89e-03
GO:0003899 DNA-directed 5’-3’ RNA polymerase activity	10	7.20e-03	0.491000	1.40e-01
GO:0006120 mitochondrial electron transport, NADH to ubiquinone	19	3.28e-04	-0.476000	2.77e-02
GO:0006268 DNA unwinding involved in DNA replication	14	2.15e-03	0.474000	7.32e-02
GO:0071806 protein transmembrane transport	12	4.79e-03	-0.470000	1.08e-01
GO:0022626 cytosolic ribosome	13	3.38e-03	0.470000	9.09e-02
GO:0006749 glutathione metabolic process	15	1.72e-03	-0.468000	6.63e-02
GO:0034314 Arp2/3 complex-mediated actin nucleation	11	7.48e-03	-0.466000	1.43e-01
GO:0006337 nucleosome disassembly	10	1.08e-02	0.466000	1.67e-01
GO:0060047 heart contraction	10	1.15e-02	-0.461000	1.71e-01
GO:0072583 clathrin-dependent endocytosis	19	5.43e-04	-0.458000	3.21e-02
GO:0030658 transport vesicle membrane	13	4.32e-03	-0.457000	1.01e-01
GO:1904646 cellular response to amyloid-beta	10	1.34e-02	-0.452000	1.82e-01
GO:0046326 positive regulation of D-glucose import	14	4.21e-03	-0.442000	9.95e-02
GO:0007129 homologous chromosome pairing at meiosis	13	6.37e-03	0.437000	1.28e-01
GO:0045271 respiratory chain complex I	31	2.58e-05	-0.437000	5.09e-03
GO:0016581 NuRD complex	10	1.71e-02	0.436000	2.09e-01
GO:0033344 cholesterol efflux	12	9.10e-03	-0.435000	1.52e-01
GO:1990391 DNA repair complex	10	1.76e-02	0.434000	2.12e-01
GO:0030904 retromer complex	15	3.73e-03	-0.433000	9.59e-02
GO:0050829 defense response to Gram-negative bacterium	11	1.30e-02	0.433000	1.82e-01
GO:0035371 microtubule plus-end	12	9.88e-03	0.430000	1.62e-01
GO:0070530 K63-linked polyubiquitin modification-dependent protein binding	17	2.20e-03	0.429000	7.37e-02
GO:0030282 bone mineralization	23	3.71e-04	-0.429000	2.97e-02
GO:0035855 megakaryocyte development	10	1.90e-02	0.429000	2.17e-01
GO:0140662 ATP-dependent protein folding chaperone	23	3.85e-04	0.428000	2.97e-02
GO:0030501 positive regulation of bone mineralization	13	7.76e-03	-0.427000	1.43e-01
GO:0001968 fibronectin binding	10	1.97e-02	0.426000	2.20e-01
GO:0006352 DNA-templated transcription initiation	11	1.49e-02	0.424000	1.95e-01
GO:1990498 mitotic spindle microtubule	10	2.05e-02	0.423000	2.23e-01
GO:0005158 insulin receptor binding	13	8.63e-03	-0.421000	1.51e-01
GO:0010811 positive regulation of cell-substrate adhesion	13	8.77e-03	-0.420000	1.51e-01
GO:0003735 structural constituent of ribosome	118	4.37e-15	-0.418000	7.75e-12
GO:0005049 nuclear export signal receptor activity	10	2.27e-02	0.416000	2.37e-01
GO:0007042 lysosomal lumen acidification	10	2.54e-02	-0.408000	2.52e-01
GO:0043024 ribosomal small subunit binding	13	1.10e-02	0.407000	1.67e-01
GO:0030515 snoRNA binding	14	8.35e-03	0.407000	1.50e-01
GO:0009749 response to glucose	14	8.46e-03	0.406000	1.50e-01
GO:0007339 binding of sperm to zona pellucida	11	1.97e-02	0.406000	2.20e-01
GO:0008143 poly(A) binding	13	1.23e-02	0.401000	1.77e-01
GO:0006396 RNA processing	21	1.51e-03	0.400000	6.53e-02
GO:0000245 spliceosomal complex assembly	10	2.89e-02	0.399000	2.66e-01
GO:0006270 DNA replication initiation	19	2.65e-03	0.398000	7.85e-02
GO:0000400 four-way junction DNA binding	14	1.05e-02	0.395000	1.66e-01
GO:0006400 tRNA modification	11	2.36e-02	0.394000	2.38e-01
GO:0060828 regulation of canonical Wnt signaling pathway	18	3.87e-03	-0.393000	9.67e-02
GO:0031681 G-protein beta-subunit binding	10	3.15e-02	-0.393000	2.75e-01
GO:0009888 tissue development	18	3.99e-03	0.392000	9.68e-02
GO:0060379 cardiac muscle cell myoblast differentiation	10	3.21e-02	0.391000	2.75e-01
GO:0061775 cohesin loader activity	24	9.54e-04	0.390000	4.70e-02
GO:1990518 single-stranded 3’-5’ DNA helicase activity	11	2.59e-02	0.388000	2.54e-01
GO:0032585 multivesicular body membrane	12	2.12e-02	-0.384000	2.26e-01
GO:0043138 3’-5’ DNA helicase activity	10	3.62e-02	0.383000	2.82e-01
GO:0045190 isotype switching	13	1.70e-02	0.382000	2.09e-01
GO:0003678 DNA helicase activity	20	3.15e-03	0.381000	8.86e-02
GO:0045943 positive regulation of transcription by RNA polymerase I	11	2.85e-02	0.381000	2.66e-01
GO:1902358 sulfate transmembrane transport	10	3.72e-02	-0.381000	2.84e-01
GO:0006913 nucleocytoplasmic transport	18	5.26e-03	0.380000	1.14e-01
GO:0140584 chromatin extrusion motor activity	23	1.70e-03	0.378000	6.63e-02
GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity	23	1.70e-03	0.378000	6.63e-02
GO:0140849 ATP-dependent H2AZ histone chaperone activity	23	1.70e-03	0.378000	6.63e-02
GO:0140672 ATAC complex	11	2.99e-02	0.378000	2.71e-01
GO:0050796 regulation of insulin secretion	12	2.36e-02	0.378000	2.38e-01
GO:0017056 structural constituent of nuclear pore	19	4.40e-03	0.377000	1.01e-01
GO:0019216 regulation of lipid metabolic process	10	4.08e-02	-0.374000	3.00e-01
GO:0042474 middle ear morphogenesis	10	4.15e-02	-0.372000	3.01e-01
GO:0002181 cytoplasmic translation	27	8.86e-04	-0.370000	4.64e-02
GO:0061462 protein localization to lysosome	10	4.30e-02	-0.370000	3.04e-01
GO:2000378 negative regulation of reactive oxygen species metabolic process	10	4.38e-02	-0.368000	3.07e-01
GO:0000723 telomere maintenance	29	6.05e-04	0.368000	3.47e-02
GO:0006298 mismatch repair	16	1.11e-02	0.367000	1.67e-01
GO:0030687 preribosome, large subunit precursor	12	2.85e-02	0.365000	2.66e-01
GO:0034045 phagophore assembly site membrane	12	2.85e-02	-0.365000	2.66e-01
GO:0008137 NADH dehydrogenase (ubiquinone) activity	10	4.56e-02	-0.365000	3.16e-01
GO:0009982 pseudouridine synthase activity	12	3.04e-02	0.361000	2.72e-01
GO:0140588 chromatin looping	27	1.24e-03	0.359000	5.95e-02
GO:0048026 positive regulation of mRNA splicing, via spliceosome	12	3.16e-02	0.358000	2.75e-01
GO:0005828 kinetochore microtubule	10	5.03e-02	-0.358000	3.29e-01
GO:0033017 sarcoplasmic reticulum membrane	10	5.04e-02	-0.357000	3.29e-01
GO:0032206 positive regulation of telomere maintenance	14	2.07e-02	0.357000	2.23e-01
GO:0005044 scavenger receptor activity	10	5.15e-02	-0.356000	3.32e-01
GO:0042026 protein refolding	12	3.34e-02	0.355000	2.75e-01
GO:0007611 learning or memory	15	1.84e-02	-0.352000	2.16e-01
GO:0016529 sarcoplasmic reticulum	14	2.30e-02	-0.351000	2.37e-01
GO:0032981 mitochondrial respiratory chain complex I assembly	38	1.95e-04	-0.349000	2.16e-02
GO:0051603 proteolysis involved in protein catabolic process	23	3.82e-03	-0.348000	9.67e-02
GO:0006509 membrane protein ectodomain proteolysis	15	2.00e-02	-0.347000	2.21e-01
GO:0032212 positive regulation of telomere maintenance via telomerase	17	1.35e-02	0.346000	1.82e-01
GO:0030500 regulation of bone mineralization	12	3.93e-02	-0.344000	2.96e-01
GO:0034727 piecemeal microautophagy of the nucleus	13	3.30e-02	-0.342000	2.75e-01
GO:0006412 translation	96	7.57e-09	-0.341000	4.48e-06
GO:0002088 lens development in camera-type eye	12	4.07e-02	-0.341000	3.00e-01
GO:0038061 non-canonical NF-kappaB signal transduction	11	5.02e-02	0.341000	3.29e-01
GO:0035925 mRNA 3’-UTR AU-rich region binding	13	3.33e-02	0.341000	2.75e-01
GO:0051881 regulation of mitochondrial membrane potential	14	2.72e-02	-0.341000	2.61e-01
GO:0061709 reticulophagy	15	2.23e-02	-0.341000	2.35e-01
GO:0005666 RNA polymerase III complex	12	4.20e-02	0.339000	3.01e-01
GO:2001222 regulation of neuron migration	10	6.37e-02	-0.339000	3.77e-01
GO:0051017 actin filament bundle assembly	12	4.23e-02	-0.339000	3.01e-01
GO:0006730 one-carbon metabolic process	13	3.46e-02	0.338000	2.76e-01
GO:0070098 chemokine-mediated signaling pathway	10	6.47e-02	0.337000	3.77e-01
GO:0036342 post-anal tail morphogenesis	10	6.53e-02	0.337000	3.78e-01
GO:0051028 mRNA transport	27	2.49e-03	0.336000	7.78e-02
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	11	5.53e-02	-0.334000	3.46e-01
GO:0043408 regulation of MAPK cascade	21	8.13e-03	0.334000	1.47e-01
GO:0008266 poly(U) RNA binding	16	2.09e-02	0.334000	2.23e-01
GO:0071577 zinc ion transmembrane transport	11	5.54e-02	-0.334000	3.46e-01
GO:0004693 cyclin-dependent protein serine/threonine kinase activity	10	7.02e-02	0.331000	3.80e-01
GO:0009968 negative regulation of signal transduction	14	3.25e-02	-0.330000	2.75e-01
GO:0060348 bone development	28	2.70e-03	-0.328000	7.85e-02
GO:0045821 positive regulation of glycolytic process	10	7.35e-02	-0.327000	3.89e-01
GO:0048705 skeletal system morphogenesis	15	2.87e-02	-0.326000	2.66e-01
GO:0051018 protein kinase A binding	12	5.04e-02	-0.326000	3.29e-01
GO:0015908 fatty acid transport	11	6.14e-02	0.326000	3.70e-01
GO:0009306 protein secretion	20	1.17e-02	-0.326000	1.72e-01
GO:0045177 apical part of cell	35	8.70e-04	-0.325000	4.64e-02
GO:0005978 glycogen biosynthetic process	11	6.19e-02	-0.325000	3.70e-01
GO:0140664 ATP-dependent DNA damage sensor activity	14	3.57e-02	0.324000	2.82e-01
GO:0043596 nuclear replication fork	10	7.65e-02	0.324000	3.95e-01
GO:0030326 embryonic limb morphogenesis	14	3.62e-02	-0.323000	2.82e-01
GO:0030031 cell projection assembly	10	7.68e-02	-0.323000	3.95e-01
GO:0005834 heterotrimeric G-protein complex	20	1.25e-02	-0.323000	1.78e-01
GO:0007004 telomere maintenance via telomerase	11	6.47e-02	0.322000	3.77e-01
GO:0060079 excitatory postsynaptic potential	15	3.19e-02	-0.320000	2.75e-01
GO:0031573 mitotic intra-S DNA damage checkpoint signaling	11	6.67e-02	0.319000	3.80e-01
GO:0061631 ubiquitin conjugating enzyme activity	24	6.84e-03	-0.319000	1.35e-01
GO:0046875 ephrin receptor binding	17	2.29e-02	0.319000	2.37e-01
GO:1903543 positive regulation of exosomal secretion	10	8.26e-02	-0.317000	4.11e-01
GO:0051302 regulation of cell division	11	6.87e-02	0.317000	3.80e-01
GO:0006936 muscle contraction	10	8.36e-02	-0.316000	4.13e-01
GO:0034707 chloride channel complex	11	7.01e-02	0.315000	3.80e-01
GO:0007131 reciprocal meiotic recombination	12	5.91e-02	0.315000	3.63e-01
GO:0002218 activation of innate immune response	17	2.47e-02	0.315000	2.47e-01
GO:0005868 cytoplasmic dynein complex	14	4.18e-02	-0.314000	3.01e-01
GO:0003689 DNA clamp loader activity	32	2.12e-03	0.314000	7.32e-02
GO:0001657 ureteric bud development	14	4.24e-02	0.313000	3.01e-01
GO:0001570 vasculogenesis	26	5.76e-03	0.313000	1.22e-01
GO:0005771 multivesicular body	21	1.31e-02	-0.313000	1.82e-01
GO:0040014 regulation of multicellular organism growth	12	6.11e-02	-0.312000	3.70e-01
GO:0006869 lipid transport	29	3.64e-03	-0.312000	9.50e-02
GO:0045070 positive regulation of viral genome replication	19	1.86e-02	0.312000	2.16e-01
GO:0008089 anterograde axonal transport	10	8.78e-02	-0.312000	4.18e-01
GO:0019003 GDP binding	44	4.10e-04	-0.308000	2.97e-02
GO:0006744 ubiquinone biosynthetic process	11	7.74e-02	-0.308000	3.95e-01
GO:0032508 DNA duplex unwinding	44	4.19e-04	0.307000	2.97e-02
GO:0031669 cellular response to nutrient levels	13	5.53e-02	0.307000	3.46e-01
GO:0098869 cellular oxidant detoxification	28	5.31e-03	-0.304000	1.14e-01
GO:0010569 regulation of double-strand break repair via homologous recombination	10	9.57e-02	0.304000	4.35e-01
GO:0032722 positive regulation of chemokine production	11	8.12e-02	-0.304000	4.08e-01
GO:0071782 endoplasmic reticulum tubular network	12	6.95e-02	0.303000	3.80e-01
GO:0015030 Cajal body	26	7.67e-03	0.302000	1.43e-01
GO:0005815 microtubule organizing center	37	1.50e-03	0.302000	6.53e-02
GO:0017022 myosin binding	11	8.35e-02	-0.301000	4.13e-01
GO:0008154 actin polymerization or depolymerization	12	7.08e-02	-0.301000	3.80e-01
GO:0034704 calcium channel complex	10	1.00e-01	-0.300000	4.42e-01
GO:1904019 epithelial cell apoptotic process	13	6.17e-02	-0.299000	3.70e-01
GO:0006865 amino acid transport	11	8.77e-02	0.297000	4.18e-01
GO:0060045 positive regulation of cardiac muscle cell proliferation	12	7.50e-02	0.297000	3.92e-01
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	15	4.68e-02	0.297000	3.22e-01
GO:0016446 somatic hypermutation of immunoglobulin genes	10	1.05e-01	0.296000	4.50e-01
GO:0003180 aortic valve morphogenesis	11	8.97e-02	-0.296000	4.24e-01
GO:0000422 autophagy of mitochondrion	14	5.66e-02	-0.294000	3.51e-01
GO:0140627 ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	10	1.07e-01	0.294000	4.52e-01
GO:0046329 negative regulation of JNK cascade	12	7.85e-02	-0.293000	3.99e-01
GO:0007338 single fertilization	19	2.70e-02	-0.293000	2.61e-01
GO:0008233 peptidase activity	10	1.09e-01	-0.293000	4.53e-01
GO:0140693 molecular condensate scaffold activity	24	1.36e-02	0.291000	1.83e-01
GO:0030073 insulin secretion	13	6.99e-02	0.290000	3.80e-01
GO:0080008 Cul4-RING E3 ubiquitin ligase complex	13	7.09e-02	0.289000	3.80e-01
GO:0006364 rRNA processing	65	5.57e-05	0.289000	7.43e-03
GO:0000781 chromosome, telomeric region	75	1.75e-05	0.287000	3.89e-03
GO:0032968 positive regulation of transcription elongation by RNA polymerase II	15	5.54e-02	0.286000	3.46e-01
GO:0048146 positive regulation of fibroblast proliferation	18	3.61e-02	0.285000	2.82e-01
GO:0061608 nuclear import signal receptor activity	14	6.65e-02	0.283000	3.80e-01
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator	11	1.04e-01	0.283000	4.46e-01
GO:0005657 replication fork	20	2.89e-02	0.282000	2.66e-01
GO:0032715 negative regulation of interleukin-6 production	14	6.76e-02	-0.282000	3.80e-01
GO:0019915 lipid storage	11	1.06e-01	-0.281000	4.51e-01
GO:0038066 p38MAPK cascade	12	9.29e-02	0.280000	4.32e-01
GO:0047496 vesicle transport along microtubule	11	1.08e-01	-0.280000	4.52e-01
GO:0004683 calcium/calmodulin-dependent protein kinase activity	11	1.10e-01	-0.278000	4.53e-01
GO:0016514 SWI/SNF complex	20	3.15e-02	0.278000	2.75e-01
GO:0001578 microtubule bundle formation	16	5.49e-02	0.277000	3.46e-01
GO:0071347 cellular response to interleukin-1	17	4.90e-02	0.276000	3.28e-01
GO:0030097 hemopoiesis	24	1.95e-02	-0.275000	2.20e-01
GO:0140359 ABC-type transporter activity	11	1.14e-01	-0.275000	4.59e-01
GO:0031072 heat shock protein binding	26	1.52e-02	0.275000	1.97e-01
GO:0030544 Hsp70 protein binding	29	1.06e-02	0.274000	1.66e-01
GO:0004364 glutathione transferase activity	10	1.33e-01	-0.274000	4.91e-01
GO:0099560 synaptic membrane adhesion	15	6.74e-02	0.273000	3.80e-01
GO:0008333 endosome to lysosome transport	32	7.76e-03	-0.272000	1.43e-01
GO:0003925 G protein activity	18	4.64e-02	-0.271000	3.20e-01
GO:0006986 response to unfolded protein	12	1.04e-01	-0.271000	4.46e-01
GO:0090141 positive regulation of mitochondrial fission	16	6.12e-02	-0.270000	3.70e-01
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity	20	3.66e-02	0.270000	2.83e-01
GO:0007095 mitotic G2 DNA damage checkpoint signaling	30	1.06e-02	0.270000	1.66e-01
GO:0034142 toll-like receptor 4 signaling pathway	14	8.06e-02	-0.270000	4.07e-01
GO:0043923 positive regulation by host of viral transcription	12	1.06e-01	0.270000	4.51e-01
GO:0055074 calcium ion homeostasis	18	4.87e-02	-0.268000	3.27e-01
GO:0001662 behavioral fear response	12	1.10e-01	0.267000	4.53e-01
GO:0019955 cytokine binding	13	9.58e-02	-0.267000	4.35e-01
GO:0017147 Wnt-protein binding	18	5.14e-02	-0.265000	3.32e-01
GO:0000380 alternative mRNA splicing, via spliceosome	16	6.72e-02	0.264000	3.80e-01
GO:0006376 mRNA splice site recognition	12	1.13e-01	0.264000	4.59e-01
GO:0043488 regulation of mRNA stability	16	6.81e-02	0.263000	3.80e-01
GO:0060326 cell chemotaxis	27	1.80e-02	0.263000	2.14e-01
GO:0002102 podosome	19	4.74e-02	0.263000	3.22e-01
GO:0006506 GPI anchor biosynthetic process	25	2.36e-02	-0.262000	2.38e-01
GO:0042274 ribosomal small subunit biogenesis	44	2.70e-03	0.262000	7.85e-02
GO:2000042 negative regulation of double-strand break repair via homologous recombination	16	7.05e-02	0.261000	3.80e-01
GO:0008045 motor neuron axon guidance	12	1.20e-01	0.259000	4.70e-01
GO:0031334 positive regulation of protein-containing complex assembly	17	6.44e-02	-0.259000	3.77e-01
GO:0032008 positive regulation of TOR signaling	12	1.23e-01	-0.257000	4.73e-01
GO:0031683 G-protein beta/gamma-subunit complex binding	10	1.59e-01	-0.257000	5.50e-01
GO:0032007 negative regulation of TOR signaling	19	5.35e-02	-0.256000	3.40e-01
GO:0050905 neuromuscular process	10	1.61e-01	-0.256000	5.51e-01
GO:0048255 mRNA stabilization	16	7.66e-02	0.256000	3.95e-01
GO:0003697 single-stranded DNA binding	67	3.01e-04	0.256000	2.69e-02
GO:0036158 outer dynein arm assembly	10	1.62e-01	0.255000	5.51e-01
GO:0008094 ATP-dependent activity, acting on DNA	11	1.43e-01	0.255000	5.14e-01
GO:0034614 cellular response to reactive oxygen species	17	6.87e-02	-0.255000	3.80e-01
GO:0042073 intraciliary transport	16	7.74e-02	-0.255000	3.95e-01
GO:0008139 nuclear localization sequence binding	13	1.12e-01	0.254000	4.58e-01
GO:0043409 negative regulation of MAPK cascade	20	5.00e-02	0.253000	3.29e-01
GO:0000792 heterochromatin	19	5.63e-02	0.253000	3.51e-01
GO:0050661 NADP binding	13	1.14e-01	-0.253000	4.59e-01
GO:0042645 mitochondrial nucleoid	37	7.80e-03	0.253000	1.43e-01
GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	12	1.30e-01	-0.253000	4.86e-01
GO:2000786 positive regulation of autophagosome assembly	14	1.03e-01	-0.252000	4.46e-01
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	13	1.18e-01	0.250000	4.65e-01
GO:0090303 positive regulation of wound healing	11	1.51e-01	-0.250000	5.32e-01
GO:0032040 small-subunit processome	59	8.89e-04	0.250000	4.64e-02
GO:0008021 synaptic vesicle	47	3.10e-03	-0.249000	8.86e-02
GO:0006261 DNA-templated DNA replication	18	6.85e-02	0.248000	3.80e-01
GO:0030992 intraciliary transport particle B	15	9.65e-02	-0.248000	4.35e-01
GO:0035269 protein O-linked mannosylation	13	1.22e-01	0.248000	4.71e-01
GO:0120162 positive regulation of cold-induced thermogenesis	30	1.92e-02	-0.247000	2.19e-01
GO:0070411 I-SMAD binding	11	1.57e-01	-0.247000	5.41e-01
GO:0048013 ephrin receptor signaling pathway	24	3.65e-02	0.247000	2.83e-01
GO:0046966 nuclear thyroid hormone receptor binding	15	9.83e-02	0.247000	4.40e-01
GO:0006397 mRNA processing	72	3.03e-04	0.246000	2.69e-02
GO:0000791 euchromatin	29	2.21e-02	0.246000	2.33e-01
GO:1904115 axon cytoplasm	25	3.37e-02	-0.245000	2.75e-01
GO:0033617 mitochondrial cytochrome c oxidase assembly	13	1.26e-01	-0.245000	4.80e-01
GO:0016197 endosomal transport	27	2.80e-02	-0.244000	2.66e-01
GO:0004602 glutathione peroxidase activity	12	1.43e-01	-0.244000	5.14e-01
GO:0042162 telomeric DNA binding	20	5.95e-02	0.243000	3.63e-01
GO:0042100 B cell proliferation	13	1.29e-01	0.243000	4.85e-01
GO:0022604 regulation of cell morphogenesis	14	1.15e-01	0.243000	4.59e-01
GO:0000974 Prp19 complex	10	1.83e-01	0.243000	5.83e-01
GO:0090128 regulation of synapse maturation	11	1.63e-01	-0.243000	5.54e-01
GO:0032465 regulation of cytokinesis	23	4.39e-02	0.243000	3.07e-01
GO:0140311 protein sequestering activity	18	7.48e-02	0.243000	3.92e-01
GO:0030218 erythrocyte differentiation	27	2.94e-02	-0.242000	2.69e-01
GO:0031468 nuclear membrane reassembly	11	1.64e-01	-0.242000	5.55e-01
GO:0072593 reactive oxygen species metabolic process	16	9.45e-02	-0.241000	4.35e-01
GO:0000502 proteasome complex	13	1.32e-01	-0.241000	4.89e-01
GO:0070372 regulation of ERK1 and ERK2 cascade	12	1.49e-01	0.240000	5.29e-01
GO:0005385 zinc ion transmembrane transporter activity	16	9.65e-02	-0.240000	4.35e-01
GO:0032039 integrator complex	15	1.08e-01	0.240000	4.52e-01
GO:0006935 chemotaxis	14	1.21e-01	-0.239000	4.71e-01
GO:0051537 2 iron, 2 sulfur cluster binding	17	8.79e-02	-0.239000	4.18e-01
GO:0045454 cell redox homeostasis	20	6.43e-02	-0.239000	3.77e-01
GO:0007249 canonical NF-kappaB signal transduction	18	8.00e-02	0.238000	4.06e-01
GO:0042130 negative regulation of T cell proliferation	12	1.53e-01	-0.238000	5.35e-01
GO:0016180 snRNA processing	10	1.93e-01	0.238000	6.01e-01
GO:0048538 thymus development	21	5.92e-02	-0.238000	3.63e-01
GO:0050808 synapse organization	16	9.98e-02	-0.238000	4.42e-01
GO:0006260 DNA replication	34	1.65e-02	0.238000	2.06e-01
GO:0060391 positive regulation of SMAD protein signal transduction	13	1.39e-01	-0.237000	5.08e-01
GO:0045109 intermediate filament organization	10	1.94e-01	-0.237000	6.01e-01
GO:0006094 gluconeogenesis	20	6.69e-02	-0.237000	3.80e-01
GO:0031462 Cul2-RING ubiquitin ligase complex	15	1.13e-01	0.236000	4.59e-01
GO:2000811 negative regulation of anoikis	10	1.96e-01	0.236000	6.01e-01
GO:0003724 RNA helicase activity	37	1.32e-02	0.235000	1.82e-01
GO:0006334 nucleosome assembly	27	3.45e-02	0.235000	2.76e-01
GO:0046854 phosphatidylinositol phosphate biosynthetic process	18	8.57e-02	0.234000	4.18e-01
GO:0036126 sperm flagellum	33	2.00e-02	-0.234000	2.21e-01
GO:0035025 positive regulation of Rho protein signal transduction	10	2.01e-01	-0.234000	6.07e-01
GO:0031201 SNARE complex	33	2.03e-02	-0.234000	2.22e-01
GO:0043536 positive regulation of blood vessel endothelial cell migration	18	8.68e-02	0.233000	4.18e-01
GO:0016579 protein deubiquitination	28	3.32e-02	0.233000	2.75e-01
GO:0010212 response to ionizing radiation	24	4.87e-02	0.233000	3.27e-01
GO:0034497 protein localization to phagophore assembly site	11	1.82e-01	-0.232000	5.83e-01
GO:0016236 macroautophagy	16	1.09e-01	-0.232000	4.53e-01
GO:0005762 mitochondrial large ribosomal subunit	38	1.38e-02	-0.231000	1.84e-01
GO:0045184 establishment of protein localization	17	9.92e-02	-0.231000	4.42e-01
GO:0048018 receptor ligand activity	19	8.21e-02	-0.230000	4.11e-01
GO:2000045 regulation of G1/S transition of mitotic cell cycle	18	9.09e-02	-0.230000	4.26e-01
GO:0050750 low-density lipoprotein particle receptor binding	13	1.51e-01	-0.230000	5.32e-01
GO:0005109 frizzled binding	17	1.00e-01	-0.230000	4.42e-01
GO:0051082 unfolded protein binding	57	2.69e-03	0.230000	7.85e-02
GO:0017116 single-stranded DNA helicase activity	16	1.12e-01	0.229000	4.58e-01
GO:0050772 positive regulation of axonogenesis	12	1.69e-01	-0.229000	5.62e-01
GO:0016460 myosin II complex	12	1.71e-01	-0.228000	5.62e-01
GO:0045505 dynein intermediate chain binding	18	9.35e-02	-0.228000	4.33e-01
GO:0009566 fertilization	13	1.55e-01	0.228000	5.38e-01
GO:0032456 endocytic recycling	42	1.07e-02	-0.228000	1.67e-01
GO:0007017 microtubule-based process	11	1.92e-01	0.227000	6.00e-01
GO:0007076 mitotic chromosome condensation	10	2.13e-01	0.227000	6.26e-01
GO:0007264 small GTPase-mediated signal transduction	46	7.81e-03	-0.227000	1.43e-01
GO:0007608 sensory perception of smell	11	1.95e-01	-0.226000	6.01e-01
GO:0070412 R-SMAD binding	13	1.60e-01	0.225000	5.50e-01
GO:0106222 lncRNA binding	17	1.09e-01	0.224000	4.53e-01
GO:0012506 vesicle membrane	15	1.33e-01	-0.224000	4.91e-01
GO:0008344 adult locomotory behavior	23	6.31e-02	-0.224000	3.76e-01
GO:1990166 protein localization to site of double-strand break	10	2.20e-01	0.224000	6.33e-01
GO:0031466 Cul5-RING ubiquitin ligase complex	11	1.99e-01	-0.224000	6.03e-01
GO:0051894 positive regulation of focal adhesion assembly	15	1.34e-01	0.223000	4.94e-01
GO:0048786 presynaptic active zone	10	2.23e-01	0.223000	6.38e-01
GO:0010976 positive regulation of neuron projection development	31	3.21e-02	0.223000	2.75e-01
GO:0010494 cytoplasmic stress granule	58	3.47e-03	0.222000	9.21e-02
GO:0050767 regulation of neurogenesis	14	1.51e-01	0.221000	5.32e-01
GO:0016853 isomerase activity	19	9.53e-02	0.221000	4.35e-01
GO:0000381 regulation of alternative mRNA splicing, via spliceosome	31	3.33e-02	0.221000	2.75e-01
GO:0099149 regulation of postsynaptic neurotransmitter receptor internalization	13	1.68e-01	0.221000	5.62e-01
GO:0048813 dendrite morphogenesis	20	8.74e-02	-0.221000	4.18e-01
GO:1990247 N6-methyladenosine-containing RNA reader activity	10	2.27e-01	0.221000	6.42e-01
GO:0000421 autophagosome membrane	23	6.77e-02	-0.220000	3.80e-01
GO:0008305 integrin complex	17	1.16e-01	0.220000	4.62e-01
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane	18	1.06e-01	-0.220000	4.51e-01
GO:0046332 SMAD binding	23	6.88e-02	-0.219000	3.80e-01
GO:2000300 regulation of synaptic vesicle exocytosis	19	9.99e-02	-0.218000	4.42e-01
GO:0035102 PRC1 complex	13	1.74e-01	-0.218000	5.69e-01
GO:0032391 photoreceptor connecting cilium	19	1.01e-01	-0.218000	4.42e-01
GO:0051560 mitochondrial calcium ion homeostasis	13	1.74e-01	-0.218000	5.69e-01
GO:0001778 plasma membrane repair	16	1.33e-01	-0.217000	4.91e-01
GO:0007098 centrosome cycle	17	1.22e-01	0.217000	4.71e-01
GO:0043484 regulation of RNA splicing	23	7.21e-02	0.217000	3.85e-01
GO:0006979 response to oxidative stress	49	8.75e-03	-0.217000	1.51e-01
GO:0010592 positive regulation of lamellipodium assembly	10	2.37e-01	-0.216000	6.53e-01
GO:0003727 single-stranded RNA binding	21	8.69e-02	0.216000	4.18e-01
GO:0030016 myofibril	13	1.79e-01	-0.215000	5.77e-01
GO:0005763 mitochondrial small ribosomal subunit	21	8.78e-02	-0.215000	4.18e-01
GO:0019221 cytokine-mediated signaling pathway	45	1.27e-02	-0.215000	1.79e-01
GO:0060337 type I interferon-mediated signaling pathway	10	2.42e-01	-0.214000	6.60e-01
GO:0016973 poly(A)+ mRNA export from nucleus	13	1.83e-01	0.213000	5.83e-01
GO:0051209 release of sequestered calcium ion into cytosol	19	1.08e-01	-0.213000	4.52e-01
GO:0003007 heart morphogenesis	16	1.41e-01	-0.213000	5.12e-01
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding	12	2.04e-01	-0.212000	6.13e-01
GO:0031647 regulation of protein stability	57	5.83e-03	0.211000	1.22e-01
GO:0097352 autophagosome maturation	23	8.04e-02	-0.211000	4.07e-01
GO:0071466 cellular response to xenobiotic stimulus	25	6.87e-02	0.210000	3.80e-01
GO:0045595 regulation of cell differentiation	13	1.89e-01	-0.210000	5.98e-01
GO:0007389 pattern specification process	13	1.90e-01	-0.210000	5.98e-01
GO:0051010 microtubule plus-end binding	11	2.28e-01	0.210000	6.42e-01
GO:1903076 regulation of protein localization to plasma membrane	18	1.23e-01	-0.210000	4.74e-01
GO:0070536 protein K63-linked deubiquitination	16	1.47e-01	-0.210000	5.23e-01
GO:0006465 signal peptide processing	10	2.52e-01	0.209000	6.67e-01
GO:0140861 DNA repair-dependent chromatin remodeling	14	1.75e-01	-0.209000	5.71e-01
GO:0005680 anaphase-promoting complex	13	1.92e-01	0.209000	6.00e-01
GO:0006906 vesicle fusion	15	1.62e-01	-0.208000	5.51e-01
GO:0006310 DNA recombination	23	8.40e-02	0.208000	4.14e-01
GO:0099523 presynaptic cytosol	11	2.33e-01	-0.208000	6.49e-01
GO:0032266 phosphatidylinositol-3-phosphate binding	32	4.22e-02	-0.208000	3.01e-01
GO:0048872 homeostasis of number of cells	14	1.80e-01	-0.207000	5.79e-01
GO:0045732 positive regulation of protein catabolic process	45	1.65e-02	-0.207000	2.06e-01
GO:0000149 SNARE binding	32	4.36e-02	-0.206000	3.07e-01
GO:0042407 cristae formation	11	2.37e-01	-0.206000	6.53e-01
GO:0030838 positive regulation of actin filament polymerization	26	6.94e-02	-0.206000	3.80e-01
GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction	21	1.03e-01	-0.205000	4.46e-01
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage	24	8.23e-02	0.205000	4.11e-01
GO:0051959 dynein light intermediate chain binding	17	1.44e-01	-0.205000	5.16e-01
GO:0009887 animal organ morphogenesis	34	3.91e-02	0.205000	2.95e-01
GO:0000976 transcription cis-regulatory region binding	55	8.82e-03	0.204000	1.51e-01
GO:0045335 phagocytic vesicle	36	3.42e-02	-0.204000	2.76e-01
GO:0071897 DNA biosynthetic process	12	2.21e-01	0.204000	6.34e-01
GO:0000228 nuclear chromosome	13	2.03e-01	0.204000	6.10e-01
GO:0032526 response to retinoic acid	15	1.72e-01	0.204000	5.67e-01
GO:0090102 cochlea development	13	2.06e-01	-0.203000	6.15e-01
GO:0007274 neuromuscular synaptic transmission	12	2.25e-01	0.202000	6.38e-01
GO:0045499 chemorepellent activity	20	1.18e-01	-0.202000	4.65e-01
GO:0051879 Hsp90 protein binding	26	7.47e-02	0.202000	3.92e-01
GO:0001772 immunological synapse	22	1.02e-01	-0.201000	4.45e-01
GO:0000281 mitotic cytokinesis	34	4.24e-02	-0.201000	3.01e-01
GO:0071549 cellular response to dexamethasone stimulus	11	2.50e-01	-0.201000	6.67e-01
GO:0000082 G1/S transition of mitotic cell cycle	41	2.66e-02	0.200000	2.58e-01
GO:0030168 platelet activation	11	2.51e-01	-0.200000	6.67e-01
GO:0046961 proton-transporting ATPase activity, rotational mechanism	14	1.96e-01	-0.199000	6.01e-01
GO:0030665 clathrin-coated vesicle membrane	11	2.52e-01	-0.199000	6.67e-01
GO:0071300 cellular response to retinoic acid	17	1.55e-01	0.199000	5.38e-01
GO:0006887 exocytosis	45	2.09e-02	-0.199000	2.23e-01
GO:0031594 neuromuscular junction	34	4.51e-02	0.199000	3.14e-01
GO:0051787 misfolded protein binding	12	2.34e-01	-0.199000	6.49e-01
GO:0004519 endonuclease activity	13	2.18e-01	0.197000	6.33e-01
GO:0051085 chaperone cofactor-dependent protein refolding	23	1.02e-01	0.197000	4.45e-01
GO:0035861 site of double-strand break	58	9.85e-03	0.196000	1.62e-01
GO:0004198 calcium-dependent cysteine-type endopeptidase activity	10	2.83e-01	-0.196000	7.00e-01
GO:0035615 clathrin adaptor activity	10	2.83e-01	-0.196000	7.00e-01
GO:0005694 chromosome	76	3.19e-03	0.196000	8.86e-02
GO:0022857 transmembrane transporter activity	41	3.07e-02	0.195000	2.74e-01
GO:0007519 skeletal muscle tissue development	17	1.64e-01	-0.195000	5.55e-01
GO:0090543 Flemming body	14	2.09e-01	-0.194000	6.18e-01
GO:0046488 phosphatidylinositol metabolic process	13	2.26e-01	-0.194000	6.41e-01
GO:0070507 regulation of microtubule cytoskeleton organization	15	1.94e-01	-0.194000	6.01e-01
GO:0007094 mitotic spindle assembly checkpoint signaling	19	1.44e-01	0.194000	5.16e-01
GO:0001221 transcription coregulator binding	17	1.69e-01	0.193000	5.62e-01
GO:0002376 immune system process	12	2.52e-01	0.191000	6.67e-01
GO:0030866 cortical actin cytoskeleton organization	20	1.40e-01	0.190000	5.12e-01
GO:0042981 regulation of apoptotic process	55	1.47e-02	0.190000	1.94e-01
GO:0048787 presynaptic active zone membrane	10	2.98e-01	0.190000	7.11e-01
GO:0005581 collagen trimer	21	1.32e-01	-0.190000	4.89e-01
GO:0035098 ESC/E(Z) complex	12	2.55e-01	0.190000	6.68e-01
GO:0030150 protein import into mitochondrial matrix	12	2.59e-01	-0.188000	6.71e-01
GO:0055013 cardiac muscle cell development	11	2.80e-01	-0.188000	6.97e-01
GO:0030878 thyroid gland development	14	2.24e-01	0.188000	6.38e-01
GO:0051056 regulation of small GTPase mediated signal transduction	16	1.94e-01	-0.188000	6.01e-01
GO:0005840 ribosome	43	3.34e-02	-0.188000	2.75e-01
GO:0070498 interleukin-1-mediated signaling pathway	11	2.82e-01	-0.187000	6.99e-01
GO:1900181 negative regulation of protein localization to nucleus	10	3.05e-01	0.187000	7.13e-01
GO:0051321 meiotic cell cycle	22	1.31e-01	0.186000	4.88e-01
GO:0005879 axonemal microtubule	10	3.09e-01	-0.186000	7.15e-01
GO:0071222 cellular response to lipopolysaccharide	44	3.34e-02	0.185000	2.75e-01
GO:0006884 cell volume homeostasis	13	2.48e-01	-0.185000	6.67e-01
GO:0035770 ribonucleoprotein granule	13	2.48e-01	0.185000	6.67e-01
GO:0000794 condensed nuclear chromosome	20	1.53e-01	0.185000	5.35e-01
GO:0071353 cellular response to interleukin-4	10	3.12e-01	-0.185000	7.16e-01
GO:0006275 regulation of DNA replication	24	1.18e-01	0.184000	4.65e-01
GO:0070382 exocytic vesicle	10	3.13e-01	0.184000	7.16e-01
GO:0000266 mitochondrial fission	10	3.14e-01	-0.184000	7.16e-01
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	21	1.46e-01	0.183000	5.22e-01
GO:0050728 negative regulation of inflammatory response	48	2.89e-02	-0.182000	2.66e-01
GO:0032869 cellular response to insulin stimulus	33	7.01e-02	-0.182000	3.80e-01
GO:0042813 Wnt receptor activity	13	2.57e-01	-0.182000	6.69e-01
GO:0030155 regulation of cell adhesion	19	1.70e-01	-0.182000	5.62e-01
GO:1901981 phosphatidylinositol phosphate binding	15	2.23e-01	-0.182000	6.38e-01
GO:0008013 beta-catenin binding	48	2.97e-02	-0.181000	2.71e-01
GO:0060070 canonical Wnt signaling pathway	57	1.79e-02	-0.181000	2.14e-01
GO:0042826 histone deacetylase binding	66	1.11e-02	0.181000	1.67e-01
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway	11	3.00e-01	-0.180000	7.13e-01
GO:0035115 embryonic forelimb morphogenesis	16	2.12e-01	-0.180000	6.25e-01
GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site	16	2.12e-01	-0.180000	6.25e-01
GO:0045785 positive regulation of cell adhesion	15	2.28e-01	0.180000	6.42e-01
GO:0030513 positive regulation of BMP signaling pathway	19	1.76e-01	0.180000	5.71e-01
GO:0022008 neurogenesis	31	8.42e-02	0.179000	4.14e-01
GO:0003684 damaged DNA binding	34	7.07e-02	0.179000	3.80e-01
GO:0045722 positive regulation of gluconeogenesis	11	3.04e-01	-0.179000	7.13e-01
GO:0048675 axon extension	16	2.17e-01	-0.178000	6.31e-01
GO:0009636 response to toxic substance	15	2.32e-01	-0.178000	6.49e-01
GO:0045116 protein neddylation	10	3.29e-01	-0.178000	7.35e-01
GO:0098686 hippocampal mossy fiber to CA3 synapse	18	1.91e-01	-0.178000	6.00e-01
GO:0001702 gastrulation with mouth forming second	10	3.30e-01	-0.178000	7.35e-01
GO:0000045 autophagosome assembly	52	2.66e-02	-0.178000	2.58e-01
GO:0099170 postsynaptic modulation of chemical synaptic transmission	12	2.89e-01	-0.177000	7.07e-01
GO:0003777 microtubule motor activity	23	1.42e-01	0.177000	5.14e-01
GO:0071816 tail-anchored membrane protein insertion into ER membrane	10	3.34e-01	-0.176000	7.35e-01
GO:0016301 kinase activity	14	2.53e-01	-0.176000	6.68e-01
GO:2000352 negative regulation of endothelial cell apoptotic process	14	2.55e-01	0.176000	6.68e-01
GO:0051020 GTPase binding	15	2.39e-01	-0.176000	6.56e-01
GO:0035567 non-canonical Wnt signaling pathway	14	2.55e-01	-0.176000	6.68e-01
GO:0005764 lysosome	132	5.03e-04	-0.176000	3.20e-02
GO:0044389 ubiquitin-like protein ligase binding	16	2.24e-01	-0.175000	6.38e-01
GO:0005902 microvillus	29	1.02e-01	-0.175000	4.45e-01
GO:1903077 negative regulation of protein localization to plasma membrane	14	2.56e-01	-0.175000	6.69e-01
GO:0048009 insulin-like growth factor receptor signaling pathway	31	9.25e-02	-0.175000	4.31e-01
GO:0031648 protein destabilization	32	8.82e-02	-0.174000	4.18e-01
GO:0120163 negative regulation of cold-induced thermogenesis	21	1.68e-01	-0.174000	5.62e-01
GO:0006898 receptor-mediated endocytosis	24	1.40e-01	-0.174000	5.12e-01
GO:0048027 mRNA 5’-UTR binding	19	1.89e-01	0.174000	5.98e-01
GO:0034332 adherens junction organization	13	2.78e-01	-0.174000	6.94e-01
GO:0071013 catalytic step 2 spliceosome	52	3.01e-02	0.174000	2.72e-01
GO:0019888 protein phosphatase regulator activity	16	2.29e-01	0.174000	6.42e-01
GO:0005154 epidermal growth factor receptor binding	19	1.90e-01	-0.174000	5.98e-01
GO:0001673 male germ cell nucleus	26	1.26e-01	0.174000	4.80e-01
GO:0005484 SNAP receptor activity	26	1.27e-01	-0.173000	4.83e-01
GO:0051453 regulation of intracellular pH	14	2.63e-01	0.173000	6.73e-01
GO:0045862 positive regulation of proteolysis	12	3.00e-01	0.173000	7.13e-01
GO:0044322 endoplasmic reticulum quality control compartment	11	3.22e-01	-0.173000	7.30e-01
GO:0051726 regulation of cell cycle	104	2.43e-03	0.172000	7.78e-02
GO:0000774 adenyl-nucleotide exchange factor activity	12	3.02e-01	0.172000	7.13e-01
GO:0035725 sodium ion transmembrane transport	45	4.72e-02	0.171000	3.22e-01
GO:0050769 positive regulation of neurogenesis	12	3.05e-01	0.171000	7.13e-01
GO:0045669 positive regulation of osteoblast differentiation	36	7.62e-02	-0.171000	3.95e-01
GO:0050770 regulation of axonogenesis	13	2.87e-01	0.171000	7.05e-01
GO:0032587 ruffle membrane	41	5.92e-02	0.170000	3.63e-01
GO:0007628 adult walking behavior	11	3.29e-01	0.170000	7.35e-01
GO:0032211 negative regulation of telomere maintenance via telomerase	10	3.53e-01	0.170000	7.49e-01
GO:0005901 caveola	28	1.20e-01	-0.170000	4.70e-01
GO:0010314 phosphatidylinositol-5-phosphate binding	11	3.31e-01	-0.169000	7.35e-01
GO:0031124 mRNA 3’-end processing	13	2.94e-01	0.168000	7.11e-01
GO:0031624 ubiquitin conjugating enzyme binding	17	2.32e-01	-0.168000	6.48e-01
GO:0032728 positive regulation of interferon-beta production	15	2.61e-01	0.168000	6.73e-01
GO:0030032 lamellipodium assembly	20	1.95e-01	-0.167000	6.01e-01
GO:0042593 glucose homeostasis	42	6.07e-02	-0.167000	3.69e-01
GO:0070936 protein K48-linked ubiquitination	68	1.73e-02	-0.167000	2.10e-01
GO:0001894 tissue homeostasis	13	2.97e-01	-0.167000	7.11e-01
GO:0099171 presynaptic modulation of chemical synaptic transmission	11	3.38e-01	0.167000	7.38e-01
GO:0051781 positive regulation of cell division	13	2.98e-01	-0.167000	7.11e-01
GO:0003677 DNA binding	337	1.70e-07	0.166000	7.55e-05
GO:0008076 voltage-gated potassium channel complex	22	1.77e-01	0.166000	5.75e-01
GO:0045815 transcription initiation-coupled chromatin remodeling	20	1.99e-01	0.166000	6.03e-01
GO:0005777 peroxisome	48	4.69e-02	-0.166000	3.22e-01
GO:0000086 G2/M transition of mitotic cell cycle	25	1.51e-01	0.166000	5.32e-01
GO:0070373 negative regulation of ERK1 and ERK2 cascade	30	1.16e-01	0.166000	4.62e-01
GO:0046847 filopodium assembly	10	3.66e-01	0.165000	7.52e-01
GO:0045296 cadherin binding	30	1.18e-01	-0.165000	4.65e-01
GO:1990841 promoter-specific chromatin binding	34	9.69e-02	0.165000	4.35e-01
GO:0060325 face morphogenesis	20	2.04e-01	-0.164000	6.11e-01
GO:0001658 branching involved in ureteric bud morphogenesis	17	2.42e-01	-0.164000	6.60e-01
GO:0016491 oxidoreductase activity	48	4.99e-02	-0.164000	3.29e-01
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis	14	2.89e-01	0.164000	7.07e-01
GO:0050727 regulation of inflammatory response	27	1.42e-01	-0.163000	5.14e-01
GO:2001235 positive regulation of apoptotic signaling pathway	16	2.58e-01	0.163000	6.71e-01
GO:0031623 receptor internalization	21	1.95e-01	-0.163000	6.01e-01
GO:0030509 BMP signaling pathway	37	8.61e-02	-0.163000	4.18e-01
GO:0004896 cytokine receptor activity	19	2.19e-01	-0.163000	6.33e-01
GO:0048821 erythrocyte development	15	2.76e-01	0.162000	6.93e-01
GO:0005930 axoneme	48	5.18e-02	-0.162000	3.33e-01
GO:0051539 4 iron, 4 sulfur cluster binding	34	1.02e-01	0.162000	4.45e-01
GO:0035914 skeletal muscle cell differentiation	24	1.69e-01	0.162000	5.62e-01
GO:0007059 chromosome segregation	41	7.28e-02	0.162000	3.87e-01
GO:0001750 photoreceptor outer segment	24	1.70e-01	-0.162000	5.62e-01
GO:0002039 p53 binding	44	6.33e-02	0.162000	3.76e-01
GO:0072344 rescue of stalled ribosome	26	1.53e-01	0.162000	5.36e-01
GO:0005518 collagen binding	34	1.03e-01	-0.161000	4.46e-01
GO:0071711 basement membrane organization	11	3.54e-01	-0.161000	7.49e-01
GO:0001818 negative regulation of cytokine production	11	3.54e-01	0.161000	7.49e-01
GO:0030317 flagellated sperm motility	30	1.28e-01	-0.161000	4.84e-01
GO:0031032 actomyosin structure organization	18	2.40e-01	-0.160000	6.58e-01
GO:0043240 Fanconi anaemia nuclear complex	11	3.58e-01	0.160000	7.52e-01
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway	19	2.28e-01	-0.160000	6.42e-01
GO:0060173 limb development	23	1.86e-01	-0.159000	5.90e-01
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding	13	3.21e-01	0.159000	7.29e-01
GO:0031145 anaphase-promoting complex-dependent catabolic process	14	3.03e-01	0.159000	7.13e-01
GO:0050679 positive regulation of epithelial cell proliferation	20	2.19e-01	-0.159000	6.33e-01
GO:0050714 positive regulation of protein secretion	19	2.31e-01	0.159000	6.47e-01
GO:0016740 transferase activity	23	1.88e-01	0.159000	5.95e-01
GO:0009966 regulation of signal transduction	38	9.06e-02	0.159000	4.25e-01
GO:0005005 transmembrane-ephrin receptor activity	14	3.04e-01	0.159000	7.13e-01
GO:0034113 heterotypic cell-cell adhesion	11	3.64e-01	0.158000	7.52e-01
GO:0008253 5’-nucleotidase activity	10	3.87e-01	0.158000	7.70e-01
GO:0000786 nucleosome	16	2.74e-01	-0.158000	6.91e-01
GO:0006886 intracellular protein transport	163	5.11e-04	-0.158000	3.20e-02
GO:0005811 lipid droplet	44	6.99e-02	-0.158000	3.80e-01
GO:0008654 phospholipid biosynthetic process	12	3.43e-01	-0.158000	7.42e-01
GO:0022904 respiratory electron transport chain	14	3.07e-01	-0.158000	7.13e-01
GO:0006631 fatty acid metabolic process	34	1.12e-01	-0.158000	4.58e-01
GO:0008237 metallopeptidase activity	12	3.46e-01	-0.157000	7.45e-01
GO:0001650 fibrillar center	102	6.20e-03	0.157000	1.27e-01
GO:0061484 hematopoietic stem cell homeostasis	11	3.67e-01	0.157000	7.52e-01
GO:0090443 FAR/SIN/STRIPAK complex	12	3.47e-01	-0.157000	7.45e-01
GO:0071277 cellular response to calcium ion	31	1.31e-01	-0.157000	4.88e-01
GO:1990023 mitotic spindle midzone	10	3.93e-01	0.156000	7.72e-01
GO:0048568 embryonic organ development	14	3.13e-01	-0.156000	7.16e-01
GO:0006605 protein targeting	18	2.55e-01	-0.155000	6.68e-01
GO:0005769 early endosome	140	1.56e-03	-0.155000	6.61e-02
GO:0031397 negative regulation of protein ubiquitination	33	1.24e-01	-0.155000	4.74e-01
GO:0003690 double-stranded DNA binding	35	1.13e-01	0.155000	4.59e-01
GO:0051287 NAD binding	19	2.43e-01	-0.155000	6.60e-01
GO:0007186 G protein-coupled receptor signaling pathway	90	1.14e-02	-0.154000	1.70e-01
GO:0035035 histone acetyltransferase binding	12	3.54e-01	0.154000	7.49e-01
GO:0140658 ATP-dependent chromatin remodeler activity	11	3.76e-01	0.154000	7.59e-01
GO:0042789 mRNA transcription by RNA polymerase II	25	1.83e-01	0.154000	5.83e-01
GO:0048012 hepatocyte growth factor receptor signaling pathway	17	2.73e-01	0.154000	6.90e-01
GO:0004867 serine-type endopeptidase inhibitor activity	22	2.12e-01	-0.154000	6.25e-01
GO:0048144 fibroblast proliferation	22	2.13e-01	0.153000	6.25e-01
GO:0007612 learning	13	3.38e-01	-0.153000	7.38e-01
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding	42	8.55e-02	-0.153000	4.18e-01
GO:0016485 protein processing	40	9.38e-02	-0.153000	4.34e-01
GO:0000724 double-strand break repair via homologous recombination	71	2.59e-02	0.153000	2.54e-01
GO:0000146 microfilament motor activity	21	2.25e-01	-0.153000	6.38e-01
GO:0032757 positive regulation of interleukin-8 production	16	2.90e-01	-0.153000	7.07e-01
GO:0071407 cellular response to organic cyclic compound	11	3.81e-01	-0.153000	7.64e-01
GO:0071339 MLL1 complex	18	2.63e-01	0.152000	6.73e-01
GO:0006413 translational initiation	30	1.49e-01	0.152000	5.28e-01
GO:0005977 glycogen metabolic process	13	3.42e-01	-0.152000	7.40e-01
GO:0016791 phosphatase activity	15	3.08e-01	-0.152000	7.13e-01
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT	11	3.82e-01	0.152000	7.65e-01
GO:0036297 interstrand cross-link repair	24	1.98e-01	0.152000	6.02e-01
GO:0004386 helicase activity	40	9.64e-02	0.152000	4.35e-01
GO:0030307 positive regulation of cell growth	36	1.15e-01	0.152000	4.59e-01
GO:0080025 phosphatidylinositol-3,5-bisphosphate binding	15	3.09e-01	-0.152000	7.15e-01
GO:1901223 negative regulation of non-canonical NF-kappaB signal transduction	14	3.27e-01	-0.151000	7.35e-01
GO:0010975 regulation of neuron projection development	16	2.96e-01	-0.151000	7.11e-01
GO:0009611 response to wounding	21	2.34e-01	-0.150000	6.49e-01
GO:0031902 late endosome membrane	68	3.26e-02	-0.150000	2.75e-01
GO:0042393 histone binding	95	1.18e-02	0.150000	1.72e-01
GO:0010842 retina layer formation	12	3.70e-01	0.150000	7.55e-01
GO:0000387 spliceosomal snRNP assembly	17	2.86e-01	0.150000	7.03e-01
GO:0005743 mitochondrial inner membrane	182	5.22e-04	-0.149000	3.20e-02
GO:0007229 integrin-mediated signaling pathway	44	8.67e-02	0.149000	4.18e-01
GO:0003714 transcription corepressor activity	100	1.02e-02	0.149000	1.66e-01
GO:0004497 monooxygenase activity	11	3.93e-01	-0.149000	7.72e-01
GO:0021549 cerebellum development	10	4.17e-01	0.148000	7.85e-01
GO:0050830 defense response to Gram-positive bacterium	14	3.37e-01	0.148000	7.38e-01
GO:0042626 ATPase-coupled transmembrane transporter activity	17	2.91e-01	-0.148000	7.08e-01
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	16	3.06e-01	-0.148000	7.13e-01
GO:0004622 lysophospholipase activity	10	4.19e-01	0.148000	7.85e-01
GO:0003700 DNA-binding transcription factor activity	79	2.35e-02	0.148000	2.38e-01
GO:0045292 mRNA cis splicing, via spliceosome	13	3.57e-01	0.148000	7.52e-01
GO:0044325 transmembrane transporter binding	55	5.91e-02	-0.147000	3.63e-01
GO:0006914 autophagy	44	9.16e-02	-0.147000	4.28e-01
GO:0033627 cell adhesion mediated by integrin	22	2.33e-01	0.147000	6.49e-01
GO:0008217 regulation of blood pressure	20	2.57e-01	-0.147000	6.69e-01
GO:0030295 protein kinase activator activity	21	2.46e-01	-0.146000	6.66e-01
GO:0007179 transforming growth factor beta receptor signaling pathway	49	7.71e-02	-0.146000	3.95e-01
GO:0045739 positive regulation of DNA repair	20	2.59e-01	0.146000	6.71e-01
GO:0003729 mRNA binding	145	2.50e-03	0.146000	7.78e-02
GO:0019905 syntaxin binding	25	2.08e-01	-0.145000	6.17e-01
GO:0051225 spindle assembly	21	2.49e-01	0.145000	6.67e-01
GO:0038062 protein tyrosine kinase collagen receptor activity	13	3.65e-01	0.145000	7.52e-01
GO:0030946 protein tyrosine phosphatase activity, metal-dependent	15	3.31e-01	-0.145000	7.35e-01
GO:0140793 histone H2AXY142 phosphatase activity	15	3.31e-01	-0.145000	7.35e-01
GO:0005544 calcium-dependent phospholipid binding	21	2.52e-01	-0.145000	6.67e-01
GO:0009653 anatomical structure morphogenesis	22	2.41e-01	-0.144000	6.58e-01
GO:0007288 sperm axoneme assembly	17	3.04e-01	0.144000	7.13e-01
GO:0034451 centriolar satellite	73	3.38e-02	0.144000	2.75e-01
GO:0030864 cortical actin cytoskeleton	31	1.66e-01	0.144000	5.62e-01
GO:0005516 calmodulin binding	69	3.96e-02	-0.143000	2.96e-01
GO:0003755 peptidyl-prolyl cis-trans isomerase activity	30	1.75e-01	0.143000	5.69e-01
GO:0071944 cell periphery	12	3.90e-01	0.143000	7.72e-01
GO:0042056 chemoattractant activity	11	4.11e-01	0.143000	7.83e-01
GO:0031297 replication fork processing	26	2.07e-01	0.143000	6.16e-01
GO:0030670 phagocytic vesicle membrane	20	2.68e-01	-0.143000	6.84e-01
GO:0006281 DNA repair	95	1.62e-02	0.143000	2.06e-01
GO:0008380 RNA splicing	47	9.02e-02	0.143000	4.25e-01
GO:0043022 ribosome binding	46	9.42e-02	0.143000	4.34e-01
GO:0001649 osteoblast differentiation	39	1.24e-01	-0.142000	4.74e-01
GO:0070006 metalloaminopeptidase activity	15	3.40e-01	-0.142000	7.39e-01
GO:0030490 maturation of SSU-rRNA	12	3.93e-01	0.142000	7.72e-01
GO:0005923 bicellular tight junction	50	8.23e-02	-0.142000	4.11e-01
GO:0061436 establishment of skin barrier	13	3.76e-01	0.142000	7.59e-01
GO:0003148 outflow tract septum morphogenesis	11	4.16e-01	0.142000	7.85e-01
GO:0048511 rhythmic process	25	2.20e-01	0.142000	6.33e-01
GO:0006644 phospholipid metabolic process	11	4.16e-01	0.142000	7.85e-01
GO:0010634 positive regulation of epithelial cell migration	19	2.86e-01	-0.142000	7.03e-01
GO:0007626 locomotory behavior	28	1.95e-01	-0.141000	6.01e-01
GO:0006891 intra-Golgi vesicle-mediated transport	18	2.99e-01	-0.141000	7.11e-01
GO:0014069 postsynaptic density	96	1.67e-02	-0.141000	2.08e-01
GO:1901673 regulation of mitotic spindle assembly	16	3.28e-01	-0.141000	7.35e-01
GO:0005543 phospholipid binding	39	1.27e-01	0.141000	4.83e-01
GO:0050729 positive regulation of inflammatory response	21	2.63e-01	-0.141000	6.73e-01
GO:0050918 positive chemotaxis	13	3.79e-01	0.141000	7.62e-01
GO:0008180 COP9 signalosome	21	2.64e-01	0.141000	6.73e-01
GO:0008327 methyl-CpG binding	16	3.29e-01	-0.141000	7.35e-01
GO:0016459 myosin complex	26	2.15e-01	-0.141000	6.27e-01
GO:0008361 regulation of cell size	12	4.00e-01	-0.140000	7.75e-01
GO:0042254 ribosome biogenesis	16	3.31e-01	0.140000	7.35e-01
GO:0070064 proline-rich region binding	10	4.42e-01	-0.140000	7.96e-01
GO:0043010 camera-type eye development	22	2.55e-01	-0.140000	6.68e-01
GO:0005721 pericentric heterochromatin	18	3.03e-01	0.140000	7.13e-01
GO:0005774 vacuolar membrane	10	4.43e-01	0.140000	7.96e-01
GO:0006303 double-strand break repair via nonhomologous end joining	20	2.79e-01	0.140000	6.96e-01
GO:0090316 positive regulation of intracellular protein transport	14	3.66e-01	0.140000	7.52e-01
GO:0006654 phosphatidic acid biosynthetic process	12	4.03e-01	0.139000	7.78e-01
GO:0018279 protein N-linked glycosylation via asparagine	11	4.24e-01	-0.139000	7.88e-01
GO:0070300 phosphatidic acid binding	13	3.85e-01	-0.139000	7.69e-01
GO:0000902 cell morphogenesis	55	7.47e-02	-0.139000	3.92e-01
GO:0005758 mitochondrial intermembrane space	47	9.95e-02	-0.139000	4.42e-01
GO:0051059 NF-kappaB binding	22	2.59e-01	0.139000	6.71e-01
GO:0019904 protein domain specific binding	104	1.46e-02	-0.139000	1.93e-01
GO:0046627 negative regulation of insulin receptor signaling pathway	16	3.37e-01	0.139000	7.37e-01
GO:0045765 regulation of angiogenesis	11	4.26e-01	0.139000	7.88e-01
GO:0061952 midbody abscission	14	3.71e-01	-0.138000	7.55e-01
GO:0006629 lipid metabolic process	52	8.49e-02	-0.138000	4.16e-01
GO:0006366 transcription by RNA polymerase II	73	4.14e-02	0.138000	3.01e-01
GO:0070628 proteasome binding	13	3.89e-01	-0.138000	7.72e-01
GO:0003730 mRNA 3’-UTR binding	51	8.86e-02	0.138000	4.19e-01
GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process	14	3.73e-01	0.138000	7.56e-01
GO:0042177 negative regulation of protein catabolic process	24	2.43e-01	0.138000	6.60e-01
GO:0006468 protein phosphorylation	12	4.10e-01	0.137000	7.83e-01
GO:0033173 calcineurin-NFAT signaling cascade	10	4.52e-01	-0.137000	8.01e-01
GO:0031491 nucleosome binding	25	2.35e-01	0.137000	6.51e-01
GO:0030136 clathrin-coated vesicle	29	2.02e-01	-0.137000	6.10e-01
GO:0007097 nuclear migration	15	3.61e-01	-0.136000	7.52e-01
GO:0090201 negative regulation of release of cytochrome c from mitochondria	11	4.34e-01	0.136000	7.90e-01
GO:0045773 positive regulation of axon extension	11	4.35e-01	0.136000	7.91e-01
GO:1902018 negative regulation of cilium assembly	13	3.96e-01	0.136000	7.73e-01
GO:0140326 ATPase-coupled intramembrane lipid transporter activity	11	4.35e-01	0.136000	7.91e-01
GO:0000176 nuclear exosome (RNase complex)	12	4.15e-01	0.136000	7.85e-01
GO:0071479 cellular response to ionizing radiation	22	2.71e-01	-0.136000	6.89e-01
GO:2000737 negative regulation of stem cell differentiation	12	4.17e-01	0.135000	7.85e-01
GO:0120009 intermembrane lipid transfer	16	3.49e-01	-0.135000	7.49e-01
GO:0008289 lipid binding	44	1.21e-01	-0.135000	4.71e-01
GO:0002062 chondrocyte differentiation	22	2.74e-01	-0.135000	6.91e-01
GO:0090090 negative regulation of canonical Wnt signaling pathway	69	5.34e-02	-0.135000	3.40e-01
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding	82	3.56e-02	0.134000	2.82e-01
GO:0005682 U5 snRNP	10	4.62e-01	-0.134000	8.09e-01
GO:0005801 cis-Golgi network	28	2.20e-01	-0.134000	6.33e-01
GO:0034976 response to endoplasmic reticulum stress	33	1.83e-01	-0.134000	5.83e-01
GO:0035198 miRNA binding	21	2.89e-01	0.134000	7.07e-01
GO:0005903 brush border	19	3.13e-01	-0.134000	7.16e-01
GO:0051536 iron-sulfur cluster binding	12	4.23e-01	0.134000	7.88e-01
GO:0038084 vascular endothelial growth factor signaling pathway	23	2.68e-01	0.133000	6.84e-01
GO:0030020 extracellular matrix structural constituent conferring tensile strength	19	3.15e-01	0.133000	7.17e-01
GO:0044331 cell-cell adhesion mediated by cadherin	12	4.24e-01	-0.133000	7.88e-01
GO:0031116 positive regulation of microtubule polymerization	11	4.45e-01	0.133000	7.97e-01
GO:0030183 B cell differentiation	26	2.41e-01	-0.133000	6.58e-01
GO:0006351 DNA-templated transcription	36	1.68e-01	0.133000	5.62e-01
GO:0007064 mitotic sister chromatid cohesion	10	4.68e-01	0.133000	8.14e-01
GO:0042572 retinol metabolic process	13	4.08e-01	-0.133000	7.81e-01
GO:0035023 regulation of Rho protein signal transduction	16	3.59e-01	-0.132000	7.52e-01
GO:0090314 positive regulation of protein targeting to membrane	12	4.27e-01	-0.132000	7.88e-01
GO:0001782 B cell homeostasis	11	4.47e-01	-0.132000	7.99e-01
GO:0003676 nucleic acid binding	106	1.89e-02	0.132000	2.17e-01
GO:0045216 cell-cell junction organization	13	4.10e-01	0.132000	7.83e-01
GO:0050839 cell adhesion molecule binding	20	3.08e-01	-0.132000	7.13e-01
GO:0043997 histone H4K12 acetyltransferase activity	10	4.71e-01	0.132000	8.14e-01
GO:0060216 definitive hemopoiesis	10	4.71e-01	-0.132000	8.14e-01
GO:0045648 positive regulation of erythrocyte differentiation	18	3.33e-01	0.132000	7.35e-01
GO:0003723 RNA binding	373	1.47e-05	0.131000	3.89e-03
GO:0043995 histone H4K5 acetyltransferase activity	10	4.73e-01	0.131000	8.14e-01
GO:0043996 histone H4K8 acetyltransferase activity	10	4.73e-01	0.131000	8.14e-01
GO:0030041 actin filament polymerization	16	3.64e-01	-0.131000	7.52e-01
GO:0031464 Cul4A-RING E3 ubiquitin ligase complex	10	4.73e-01	0.131000	8.14e-01
GO:0032731 positive regulation of interleukin-1 beta production	11	4.52e-01	-0.131000	8.01e-01
GO:0019722 calcium-mediated signaling	32	2.00e-01	-0.131000	6.06e-01
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding	83	4.03e-02	-0.130000	2.99e-01
GO:0000278 mitotic cell cycle	54	9.78e-02	0.130000	4.38e-01
GO:0005876 spindle microtubule	20	3.14e-01	-0.130000	7.16e-01
GO:0032743 positive regulation of interleukin-2 production	16	3.68e-01	-0.130000	7.53e-01
GO:0060339 negative regulation of type I interferon-mediated signaling pathway	13	4.18e-01	0.130000	7.85e-01
GO:0000049 tRNA binding	52	1.06e-01	0.130000	4.51e-01
GO:0016235 aggresome	17	3.55e-01	0.129000	7.50e-01
GO:0001817 regulation of cytokine production	25	2.63e-01	-0.129000	6.73e-01
GO:0005198 structural molecule activity	38	1.69e-01	-0.129000	5.62e-01
GO:0030324 lung development	32	2.08e-01	-0.129000	6.17e-01
GO:0008168 methyltransferase activity	13	4.24e-01	0.128000	7.88e-01
GO:0030336 negative regulation of cell migration	51	1.14e-01	-0.128000	4.59e-01
GO:0016282 eukaryotic 43S preinitiation complex	14	4.07e-01	0.128000	7.81e-01
GO:0030030 cell projection organization	13	4.26e-01	0.128000	7.88e-01
GO:0008283 cell population proliferation	66	7.37e-02	0.127000	3.89e-01
GO:0032496 response to lipopolysaccharide	37	1.81e-01	-0.127000	5.80e-01
GO:1902895 positive regulation of miRNA transcription	25	2.71e-01	0.127000	6.89e-01
GO:0005080 protein kinase C binding	17	3.64e-01	0.127000	7.52e-01
GO:0000124 SAGA complex	15	3.96e-01	0.127000	7.73e-01
GO:0030970 retrograde protein transport, ER to cytosol	12	4.48e-01	-0.127000	7.99e-01
GO:0071007 U2-type catalytic step 2 spliceosome	24	2.84e-01	-0.126000	7.00e-01
GO:0006457 protein folding	81	4.94e-02	0.126000	3.29e-01
GO:0000070 mitotic sister chromatid segregation	18	3.54e-01	0.126000	7.49e-01
GO:0030133 transport vesicle	23	2.95e-01	-0.126000	7.11e-01
GO:0016787 hydrolase activity	108	2.38e-02	0.126000	2.38e-01
GO:0000939 inner kinetochore	10	4.91e-01	0.126000	8.30e-01
GO:0034605 cellular response to heat	16	3.83e-01	0.126000	7.65e-01
GO:0014032 neural crest cell development	11	4.71e-01	0.126000	8.14e-01
GO:0030593 neutrophil chemotaxis	13	4.34e-01	-0.125000	7.90e-01
GO:0060324 face development	13	4.34e-01	-0.125000	7.90e-01
GO:0006446 regulation of translational initiation	17	3.72e-01	0.125000	7.56e-01
GO:0006974 DNA damage response	119	1.85e-02	0.125000	2.16e-01
GO:0005667 transcription regulator complex	91	3.97e-02	0.125000	2.96e-01
GO:0003785 actin monomer binding	14	4.19e-01	-0.125000	7.85e-01
GO:0035987 endodermal cell differentiation	21	3.22e-01	0.125000	7.31e-01
GO:0032993 protein-DNA complex	21	3.24e-01	0.124000	7.32e-01
GO:0012505 endomembrane system	97	3.47e-02	-0.124000	2.76e-01
GO:0008033 tRNA processing	15	4.05e-01	0.124000	7.80e-01
GO:0000407 phagophore assembly site	20	3.37e-01	-0.124000	7.37e-01
GO:0098719 sodium ion import across plasma membrane	10	4.97e-01	0.124000	8.34e-01
GO:0050885 neuromuscular process controlling balance	24	2.95e-01	-0.123000	7.11e-01
GO:0005686 U2 snRNP	16	3.93e-01	0.123000	7.72e-01
GO:0005008 hepatocyte growth factor receptor activity	13	4.42e-01	0.123000	7.96e-01
GO:0009408 response to heat	19	3.52e-01	0.123000	7.49e-01
GO:0030170 pyridoxal phosphate binding	34	2.14e-01	-0.123000	6.26e-01
GO:0061351 neural precursor cell proliferation	14	4.25e-01	0.123000	7.88e-01
GO:0006623 protein targeting to vacuole	11	4.81e-01	-0.123000	8.22e-01
GO:0070577 lysine-acetylated histone binding	16	3.96e-01	0.123000	7.73e-01
GO:0030672 synaptic vesicle membrane	45	1.55e-01	-0.123000	5.38e-01
GO:0007218 neuropeptide signaling pathway	14	4.28e-01	-0.122000	7.88e-01
GO:0001889 liver development	30	2.46e-01	-0.122000	6.66e-01
GO:0006417 regulation of translation	44	1.61e-01	0.122000	5.51e-01
GO:0070402 NADPH binding	10	5.04e-01	0.122000	8.34e-01
GO:0070830 bicellular tight junction assembly	19	3.58e-01	-0.122000	7.52e-01
GO:0017025 TBP-class protein binding	18	3.72e-01	0.122000	7.56e-01
GO:0043687 post-translational protein modification	19	3.61e-01	0.121000	7.52e-01
GO:0030159 signaling receptor complex adaptor activity	13	4.51e-01	-0.121000	8.01e-01
GO:0003682 chromatin binding	239	1.33e-03	0.121000	6.04e-02
GO:0005741 mitochondrial outer membrane	96	4.09e-02	-0.121000	3.00e-01
GO:0045494 photoreceptor cell maintenance	25	2.96e-01	-0.121000	7.11e-01
GO:0002250 adaptive immune response	20	3.51e-01	-0.121000	7.49e-01
GO:0046580 negative regulation of Ras protein signal transduction	13	4.52e-01	0.120000	8.01e-01
GO:0097060 synaptic membrane	11	4.90e-01	0.120000	8.29e-01
GO:0001937 negative regulation of endothelial cell proliferation	12	4.71e-01	-0.120000	8.14e-01
GO:0021987 cerebral cortex development	25	2.98e-01	-0.120000	7.11e-01
GO:0003887 DNA-directed DNA polymerase activity	16	4.06e-01	0.120000	7.80e-01
GO:0097730 non-motile cilium	13	4.54e-01	-0.120000	8.01e-01
GO:0004535 poly(A)-specific ribonuclease activity	10	5.12e-01	0.120000	8.38e-01
GO:0032570 response to progesterone	13	4.56e-01	0.120000	8.01e-01
GO:0005938 cell cortex	74	7.63e-02	-0.119000	3.95e-01
GO:0005021 vascular endothelial growth factor receptor activity	15	4.24e-01	0.119000	7.88e-01
GO:1900182 positive regulation of protein localization to nucleus	25	3.06e-01	0.118000	7.13e-01
GO:0071260 cellular response to mechanical stimulus	23	3.26e-01	0.118000	7.35e-01
GO:0048873 homeostasis of number of cells within a tissue	14	4.44e-01	0.118000	7.97e-01
GO:0005019 platelet-derived growth factor beta-receptor activity	13	4.60e-01	0.118000	8.07e-01
GO:0008092 cytoskeletal protein binding	16	4.13e-01	-0.118000	7.85e-01
GO:1902600 proton transmembrane transport	60	1.14e-01	-0.118000	4.59e-01
GO:0051965 positive regulation of synapse assembly	23	3.28e-01	-0.118000	7.35e-01
GO:0006284 base-excision repair	17	4.01e-01	0.118000	7.75e-01
GO:0032874 positive regulation of stress-activated MAPK cascade	11	4.99e-01	0.118000	8.34e-01
GO:0045995 regulation of embryonic development	27	2.90e-01	0.118000	7.07e-01
GO:0048010 vascular endothelial growth factor receptor signaling pathway	13	4.64e-01	0.117000	8.09e-01
GO:0051016 barbed-end actin filament capping	16	4.17e-01	-0.117000	7.85e-01
GO:1990904 ribonucleoprotein complex	104	3.91e-02	0.117000	2.95e-01
GO:0007596 blood coagulation	26	3.01e-01	-0.117000	7.13e-01
GO:0070374 positive regulation of ERK1 and ERK2 cascade	61	1.14e-01	-0.117000	4.59e-01
GO:0008543 fibroblast growth factor receptor signaling pathway	36	2.24e-01	-0.117000	6.38e-01
GO:0001503 ossification	27	2.93e-01	-0.117000	7.10e-01
GO:0001837 epithelial to mesenchymal transition	17	4.04e-01	-0.117000	7.80e-01
GO:0045747 positive regulation of Notch signaling pathway	23	3.32e-01	-0.117000	7.35e-01
GO:0007080 mitotic metaphase chromosome alignment	23	3.33e-01	-0.117000	7.35e-01
GO:0055088 lipid homeostasis	19	3.79e-01	-0.117000	7.62e-01
GO:0004930 G protein-coupled receptor activity	59	1.22e-01	-0.117000	4.71e-01
GO:0048513 animal organ development	11	5.04e-01	0.116000	8.34e-01
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand	12	4.86e-01	0.116000	8.26e-01
GO:0001664 G protein-coupled receptor binding	23	3.35e-01	0.116000	7.35e-01
GO:0010977 negative regulation of neuron projection development	18	3.94e-01	-0.116000	7.72e-01
GO:0000460 maturation of 5.8S rRNA	11	5.05e-01	0.116000	8.34e-01
GO:0005765 lysosomal membrane	139	1.83e-02	-0.116000	2.16e-01
GO:0016887 ATP hydrolysis activity	217	3.30e-03	0.116000	9.01e-02
GO:0034097 response to cytokine	12	4.87e-01	0.116000	8.27e-01
GO:0060612 adipose tissue development	23	3.36e-01	-0.116000	7.37e-01
GO:0005768 endosome	114	3.29e-02	-0.116000	2.75e-01
GO:0000175 3’-5’-RNA exonuclease activity	21	3.59e-01	0.116000	7.52e-01
GO:0005604 basement membrane	45	1.80e-01	0.116000	5.79e-01
GO:0004714 transmembrane receptor protein tyrosine kinase activity	14	4.54e-01	0.115000	8.01e-01
GO:0048536 spleen development	23	3.40e-01	-0.115000	7.39e-01
GO:0043539 protein serine/threonine kinase activator activity	33	2.53e-01	0.115000	6.68e-01
GO:0001508 action potential	10	5.29e-01	-0.115000	8.49e-01
GO:0030220 platelet formation	11	5.10e-01	0.115000	8.36e-01
GO:0042327 positive regulation of phosphorylation	13	4.74e-01	-0.115000	8.15e-01
GO:0005262 calcium channel activity	21	3.65e-01	-0.114000	7.52e-01
GO:0010575 positive regulation of vascular endothelial growth factor production	14	4.60e-01	-0.114000	8.06e-01
GO:2000648 positive regulation of stem cell proliferation	12	4.95e-01	0.114000	8.34e-01
GO:0004722 protein serine/threonine phosphatase activity	33	2.59e-01	-0.114000	6.71e-01
GO:0050681 nuclear androgen receptor binding	16	4.31e-01	-0.114000	7.89e-01
GO:0005730 nucleolus	442	4.62e-05	0.114000	7.31e-03
GO:0006488 dolichol-linked oligosaccharide biosynthetic process	14	4.63e-01	0.113000	8.09e-01
GO:0045672 positive regulation of osteoclast differentiation	12	4.97e-01	-0.113000	8.34e-01
GO:0017134 fibroblast growth factor binding	12	4.97e-01	0.113000	8.34e-01
GO:0046835 carbohydrate phosphorylation	20	3.81e-01	0.113000	7.65e-01
GO:0098552 side of membrane	16	4.34e-01	-0.113000	7.90e-01
GO:0001222 transcription corepressor binding	27	3.10e-01	-0.113000	7.15e-01
GO:0016779 nucleotidyltransferase activity	11	5.17e-01	0.113000	8.41e-01
GO:0002040 sprouting angiogenesis	18	4.08e-01	0.113000	7.81e-01
GO:0045202 synapse	166	1.25e-02	-0.113000	1.78e-01
GO:0090575 RNA polymerase II transcription regulator complex	53	1.56e-01	0.113000	5.41e-01
GO:0006635 fatty acid beta-oxidation	26	3.26e-01	-0.111000	7.35e-01
GO:0061512 protein localization to cilium	22	3.66e-01	-0.111000	7.52e-01
GO:0009617 response to bacterium	36	2.50e-01	-0.111000	6.67e-01
GO:0048839 inner ear development	12	5.09e-01	0.110000	8.36e-01
GO:0007162 negative regulation of cell adhesion	17	4.32e-01	-0.110000	7.90e-01
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle	23	3.62e-01	-0.110000	7.52e-01
GO:0006897 endocytosis	93	6.75e-02	-0.110000	3.80e-01
GO:0050680 negative regulation of epithelial cell proliferation	23	3.63e-01	-0.110000	7.52e-01
GO:0031175 neuron projection development	51	1.77e-01	-0.109000	5.75e-01
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading	25	3.45e-01	0.109000	7.44e-01
GO:0031507 heterochromatin formation	27	3.29e-01	0.108000	7.35e-01
GO:0005681 spliceosomal complex	43	2.19e-01	0.108000	6.33e-01
GO:0015701 bicarbonate transport	12	5.16e-01	0.108000	8.41e-01
GO:0010719 negative regulation of epithelial to mesenchymal transition	16	4.53e-01	0.108000	8.01e-01
GO:0048306 calcium-dependent protein binding	20	4.02e-01	-0.108000	7.78e-01
GO:0045727 positive regulation of translation	36	2.64e-01	0.108000	6.73e-01
GO:0072659 protein localization to plasma membrane	74	1.09e-01	-0.108000	4.53e-01
GO:0035278 miRNA-mediated gene silencing by inhibition of translation	13	5.02e-01	0.108000	8.34e-01
GO:0005871 kinesin complex	22	3.83e-01	0.108000	7.65e-01
GO:0005615 extracellular space	400	2.44e-04	-0.107000	2.55e-02
GO:0061157 mRNA destabilization	12	5.20e-01	-0.107000	8.42e-01
GO:0045214 sarcomere organization	12	5.21e-01	0.107000	8.42e-01
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway	41	2.36e-01	-0.107000	6.52e-01
GO:0003712 transcription coregulator activity	76	1.07e-01	0.107000	4.52e-01
GO:0005975 carbohydrate metabolic process	49	1.96e-01	-0.107000	6.01e-01
GO:0006611 protein export from nucleus	22	3.87e-01	0.106000	7.71e-01
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding	21	3.99e-01	0.106000	7.74e-01
GO:0051315 attachment of mitotic spindle microtubules to kinetochore	10	5.61e-01	0.106000	8.69e-01
GO:0032588 trans-Golgi network membrane	27	3.41e-01	-0.106000	7.40e-01
GO:0050699 WW domain binding	11	5.46e-01	0.105000	8.60e-01
GO:0031982 vesicle	26	3.53e-01	-0.105000	7.49e-01
GO:0070273 phosphatidylinositol-4-phosphate binding	17	4.54e-01	-0.105000	8.01e-01
GO:0051480 regulation of cytosolic calcium ion concentration	13	5.12e-01	-0.105000	8.38e-01
GO:0001935 endothelial cell proliferation	12	5.29e-01	-0.105000	8.49e-01
GO:0051491 positive regulation of filopodium assembly	15	4.82e-01	-0.105000	8.22e-01
GO:0010718 positive regulation of epithelial to mesenchymal transition	26	3.56e-01	-0.105000	7.51e-01
GO:0005576 extracellular region	243	5.13e-03	-0.105000	1.12e-01
GO:0035904 aorta development	15	4.85e-01	-0.104000	8.25e-01
GO:0030426 growth cone	41	2.49e-01	0.104000	6.67e-01
GO:0003743 translation initiation factor activity	39	2.61e-01	0.104000	6.73e-01
GO:0065003 protein-containing complex assembly	37	2.75e-01	0.104000	6.92e-01
GO:0030837 negative regulation of actin filament polymerization	14	5.03e-01	0.104000	8.34e-01
GO:0007275 multicellular organism development	26	3.62e-01	0.103000	7.52e-01
GO:0030521 androgen receptor signaling pathway	12	5.36e-01	-0.103000	8.54e-01
GO:0031965 nuclear membrane	120	5.12e-02	0.103000	3.32e-01
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity	19	4.37e-01	-0.103000	7.91e-01
GO:1905515 non-motile cilium assembly	38	2.73e-01	0.103000	6.90e-01
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment	36	2.86e-01	-0.103000	7.03e-01
GO:0030833 regulation of actin filament polymerization	21	4.15e-01	-0.103000	7.85e-01
GO:0050768 negative regulation of neurogenesis	10	5.74e-01	-0.103000	8.75e-01
GO:0048854 brain morphogenesis	14	5.07e-01	0.102000	8.36e-01
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway	44	2.40e-01	0.102000	6.58e-01
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle	14	5.08e-01	0.102000	8.36e-01
GO:0000226 microtubule cytoskeleton organization	69	1.43e-01	0.102000	5.14e-01
GO:0060261 positive regulation of transcription initiation by RNA polymerase II	30	3.34e-01	0.102000	7.35e-01
GO:0048008 platelet-derived growth factor receptor signaling pathway	17	4.67e-01	-0.102000	8.14e-01
GO:0004843 cysteine-type deubiquitinase activity	58	1.80e-01	0.102000	5.79e-01
GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	35	2.98e-01	-0.102000	7.11e-01
GO:0072686 mitotic spindle	70	1.41e-01	0.102000	5.13e-01
GO:0006513 protein monoubiquitination	27	3.61e-01	-0.102000	7.52e-01
GO:0000932 P-body	61	1.70e-01	0.102000	5.62e-01
GO:2000773 negative regulation of cellular senescence	12	5.43e-01	-0.102000	8.58e-01
GO:0031410 cytoplasmic vesicle	106	7.24e-02	-0.101000	3.86e-01
GO:0008408 3’-5’ exonuclease activity	10	5.81e-01	-0.101000	8.75e-01
GO:0031514 motile cilium	39	2.78e-01	-0.101000	6.94e-01
GO:0032024 positive regulation of insulin secretion	21	4.26e-01	-0.100000	7.88e-01
GO:0048741 skeletal muscle fiber development	16	4.88e-01	0.100000	8.28e-01
GO:0030165 PDZ domain binding	30	3.44e-01	-0.099900	7.42e-01
GO:0019827 stem cell population maintenance	21	4.29e-01	0.099700	7.88e-01
GO:0006367 transcription initiation at RNA polymerase II promoter	20	4.41e-01	-0.099600	7.96e-01
GO:0042605 peptide antigen binding	10	5.87e-01	-0.099300	8.75e-01
GO:0021915 neural tube development	17	4.79e-01	0.099200	8.20e-01
GO:0016829 lyase activity	15	5.06e-01	-0.099200	8.35e-01
GO:0070050 neuron cellular homeostasis	14	5.20e-01	-0.099200	8.42e-01
GO:0045766 positive regulation of angiogenesis	52	2.17e-01	0.098900	6.32e-01
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II	12	5.53e-01	-0.098900	8.67e-01
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway	12	5.53e-01	0.098900	8.67e-01
GO:0048812 neuron projection morphogenesis	30	3.50e-01	0.098600	7.49e-01
GO:0045879 negative regulation of smoothened signaling pathway	15	5.09e-01	-0.098600	8.36e-01
GO:0004674 protein serine/threonine kinase activity	203	1.57e-02	0.098600	2.02e-01
GO:0005814 centriole	92	1.04e-01	0.098300	4.46e-01
GO:0045931 positive regulation of mitotic cell cycle	14	5.25e-01	0.098200	8.46e-01
GO:0070888 E-box binding	21	4.36e-01	-0.098200	7.91e-01
GO:0035116 embryonic hindlimb morphogenesis	11	5.73e-01	-0.098100	8.75e-01
GO:0051382 kinetochore assembly	11	5.74e-01	0.098000	8.75e-01
GO:0006406 mRNA export from nucleus	28	3.70e-01	0.098000	7.55e-01
GO:0090307 mitotic spindle assembly	30	3.53e-01	0.097900	7.49e-01
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process	158	3.40e-02	-0.097900	2.75e-01
GO:0010467 gene expression	81	1.28e-01	-0.097900	4.84e-01
GO:0004177 aminopeptidase activity	13	5.42e-01	-0.097700	8.58e-01
GO:0048863 stem cell differentiation	22	4.28e-01	0.097700	7.88e-01
GO:0032760 positive regulation of tumor necrosis factor production	32	3.39e-01	-0.097700	7.38e-01
GO:0097718 disordered domain specific binding	15	5.13e-01	-0.097600	8.38e-01
GO:0071889 14-3-3 protein binding	15	5.13e-01	0.097500	8.38e-01
GO:0044782 cilium organization	13	5.43e-01	-0.097500	8.58e-01
GO:0007259 cell surface receptor signaling pathway via JAK-STAT	22	4.30e-01	-0.097300	7.88e-01
GO:0005249 voltage-gated potassium channel activity	15	5.15e-01	0.097200	8.40e-01
GO:0031901 early endosome membrane	75	1.47e-01	-0.097000	5.23e-01
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	13	5.45e-01	0.096900	8.60e-01
GO:0000398 mRNA splicing, via spliceosome	87	1.19e-01	0.096800	4.68e-01
GO:0043616 keratinocyte proliferation	11	5.81e-01	0.096100	8.75e-01
GO:0002230 positive regulation of defense response to virus by host	11	5.81e-01	0.096100	8.75e-01
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	12	5.65e-01	0.096000	8.69e-01
GO:0008023 transcription elongation factor complex	14	5.34e-01	0.095900	8.54e-01
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	32	3.49e-01	-0.095600	7.49e-01
GO:0043410 positive regulation of MAPK cascade	61	1.98e-01	-0.095400	6.03e-01
GO:0045022 early endosome to late endosome transport	19	4.72e-01	0.095400	8.14e-01
GO:0009411 response to UV	23	4.30e-01	0.095100	7.88e-01
GO:0007043 cell-cell junction assembly	10	6.03e-01	-0.094900	8.79e-01
GO:0030488 tRNA methylation	20	4.63e-01	0.094800	8.09e-01
GO:0006606 protein import into nucleus	62	1.97e-01	0.094700	6.02e-01
GO:0097431 mitotic spindle pole	27	3.95e-01	0.094700	7.73e-01
GO:0030308 negative regulation of cell growth	42	2.90e-01	0.094500	7.07e-01
GO:0004864 protein phosphatase inhibitor activity	13	5.57e-01	-0.094100	8.69e-01
GO:0005689 U12-type spliceosomal complex	20	4.68e-01	-0.093700	8.14e-01
GO:0001755 neural crest cell migration	27	4.00e-01	0.093600	7.75e-01
GO:0006952 defense response	10	6.09e-01	0.093400	8.80e-01
GO:0045600 positive regulation of fat cell differentiation	22	4.49e-01	-0.093200	8.00e-01
GO:0004521 RNA endonuclease activity	20	4.71e-01	0.093100	8.14e-01
GO:0042383 sarcolemma	36	3.34e-01	-0.093100	7.35e-01
GO:0071333 cellular response to glucose stimulus	13	5.62e-01	-0.092900	8.69e-01
GO:0046676 negative regulation of insulin secretion	11	5.94e-01	0.092900	8.76e-01
GO:0045444 fat cell differentiation	43	2.93e-01	-0.092800	7.09e-01
GO:0005509 calcium ion binding	261	1.04e-02	-0.092400	1.66e-01
GO:0001671 ATPase activator activity	18	4.98e-01	0.092200	8.34e-01
GO:0045666 positive regulation of neuron differentiation	26	4.16e-01	0.092200	7.85e-01
GO:0033290 eukaryotic 48S preinitiation complex	13	5.66e-01	0.092000	8.69e-01
GO:0043005 neuron projection	96	1.20e-01	-0.091800	4.70e-01
GO:0032868 response to insulin	22	4.56e-01	0.091800	8.01e-01
GO:0016055 Wnt signaling pathway	78	1.62e-01	-0.091700	5.51e-01
GO:0031167 rRNA methylation	11	5.99e-01	0.091700	8.79e-01
GO:0043021 ribonucleoprotein complex binding	23	4.48e-01	-0.091400	7.99e-01
GO:0048477 oogenesis	14	5.55e-01	0.091200	8.67e-01
GO:0001666 response to hypoxia	51	2.61e-01	0.091100	6.73e-01
GO:0045121 membrane raft	75	1.73e-01	-0.091000	5.69e-01
GO:1902476 chloride transmembrane transport	38	3.32e-01	-0.091000	7.35e-01
GO:0043029 T cell homeostasis	12	5.86e-01	0.090800	8.75e-01
GO:0042102 positive regulation of T cell proliferation	10	6.19e-01	-0.090800	8.86e-01
GO:0015485 cholesterol binding	28	4.07e-01	-0.090700	7.80e-01
GO:0097038 perinuclear endoplasmic reticulum	10	6.20e-01	-0.090600	8.86e-01
GO:0005905 clathrin-coated pit	30	3.92e-01	-0.090400	7.72e-01
GO:0052689 carboxylic ester hydrolase activity	12	5.88e-01	0.090400	8.75e-01
GO:0048701 embryonic cranial skeleton morphogenesis	13	5.73e-01	-0.090400	8.75e-01
GO:0010595 positive regulation of endothelial cell migration	26	4.26e-01	0.090300	7.88e-01
GO:0000242 pericentriolar material	14	5.59e-01	0.090200	8.69e-01
GO:0000159 protein phosphatase type 2A complex	12	5.91e-01	-0.089600	8.76e-01
GO:0030182 neuron differentiation	55	2.51e-01	-0.089500	6.67e-01
GO:0031333 negative regulation of protein-containing complex assembly	16	5.36e-01	0.089400	8.54e-01
GO:0071805 potassium ion transmembrane transport	38	3.42e-01	0.089100	7.40e-01
GO:0043627 response to estrogen	10	6.26e-01	0.089000	8.88e-01
GO:0001516 prostaglandin biosynthetic process	10	6.27e-01	-0.088800	8.88e-01
GO:0007492 endoderm development	10	6.27e-01	0.088700	8.88e-01
GO:0000987 cis-regulatory region sequence-specific DNA binding	21	4.82e-01	0.088700	8.22e-01
GO:0020037 heme binding	51	2.74e-01	-0.088600	6.91e-01
GO:0046716 muscle cell cellular homeostasis	15	5.53e-01	-0.088600	8.67e-01
GO:0006338 chromatin remodeling	249	1.65e-02	0.088500	2.06e-01
GO:0015035 protein-disulfide reductase activity	14	5.67e-01	-0.088400	8.69e-01
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules	38	3.47e-01	-0.088300	7.45e-01
GO:0004252 serine-type endopeptidase activity	51	2.77e-01	-0.088100	6.93e-01
GO:0030507 spectrin binding	13	5.82e-01	-0.088100	8.75e-01
GO:0097150 neuronal stem cell population maintenance	18	5.18e-01	-0.088100	8.41e-01
GO:0042273 ribosomal large subunit biogenesis	22	4.75e-01	0.088000	8.15e-01
GO:0007399 nervous system development	88	1.54e-01	-0.088000	5.37e-01
GO:0071949 FAD binding	27	4.29e-01	0.087900	7.88e-01
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	67	2.17e-01	-0.087300	6.31e-01
GO:0034220 monoatomic ion transmembrane transport	20	5.00e-01	-0.087200	8.34e-01
GO:0030334 regulation of cell migration	35	3.73e-01	-0.087100	7.56e-01
GO:0001974 blood vessel remodeling	16	5.48e-01	-0.086800	8.62e-01
GO:0001726 ruffle	43	3.26e-01	0.086700	7.35e-01
GO:0071233 cellular response to L-leucine	10	6.35e-01	0.086700	8.88e-01
GO:0000775 chromosome, centromeric region	31	4.05e-01	-0.086400	7.80e-01
GO:0005125 cytokine activity	27	4.38e-01	0.086300	7.91e-01
GO:0007368 determination of left/right symmetry	28	4.30e-01	-0.086300	7.88e-01
GO:0045111 intermediate filament cytoskeleton	23	4.75e-01	-0.086100	8.15e-01
GO:0015630 microtubule cytoskeleton	72	2.07e-01	-0.086000	6.16e-01
GO:0005685 U1 snRNP	12	6.06e-01	0.086000	8.79e-01
GO:0003713 transcription coactivator activity	127	9.61e-02	0.085600	4.35e-01
GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	77	1.96e-01	-0.085300	6.01e-01
GO:0051496 positive regulation of stress fiber assembly	31	4.13e-01	0.085100	7.85e-01
GO:0045740 positive regulation of DNA replication	11	6.27e-01	0.084500	8.88e-01
GO:0015459 potassium channel regulator activity	14	5.85e-01	-0.084300	8.75e-01
GO:0048041 focal adhesion assembly	14	5.85e-01	0.084200	8.75e-01
GO:0098794 postsynapse	66	2.37e-01	-0.084200	6.53e-01
GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway	16	5.61e-01	0.084000	8.69e-01
GO:0050804 modulation of chemical synaptic transmission	34	3.97e-01	-0.084000	7.74e-01
GO:0032924 activin receptor signaling pathway	12	6.16e-01	-0.083600	8.84e-01
GO:0005643 nuclear pore	33	4.06e-01	0.083500	7.80e-01
GO:0042632 cholesterol homeostasis	39	3.67e-01	-0.083400	7.52e-01
GO:0051721 protein phosphatase 2A binding	14	5.90e-01	0.083200	8.76e-01
GO:0032956 regulation of actin cytoskeleton organization	37	3.82e-01	-0.083100	7.65e-01
GO:0005524 ATP binding	899	3.23e-05	0.082600	5.73e-03
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway	32	4.19e-01	-0.082600	7.85e-01
GO:0042995 cell projection	54	2.95e-01	-0.082400	7.11e-01
GO:0004181 metallocarboxypeptidase activity	12	6.22e-01	0.082200	8.87e-01
GO:0044291 cell-cell contact zone	13	6.08e-01	-0.082100	8.80e-01
GO:0045746 negative regulation of Notch signaling pathway	15	5.82e-01	0.082100	8.75e-01
GO:0071346 cellular response to type II interferon	23	4.99e-01	0.081400	8.34e-01
GO:0000993 RNA polymerase II complex binding	23	5.01e-01	0.081200	8.34e-01
GO:0070847 core mediator complex	19	5.41e-01	-0.080900	8.58e-01
GO:0019838 growth factor binding	11	6.44e-01	-0.080500	8.89e-01
GO:0098656 monoatomic anion transmembrane transport	18	5.56e-01	-0.080200	8.68e-01
GO:0033209 tumor necrosis factor-mediated signaling pathway	15	5.93e-01	0.079800	8.76e-01
GO:0033962 P-body assembly	14	6.06e-01	0.079600	8.79e-01
GO:0000307 cyclin-dependent protein kinase holoenzyme complex	20	5.39e-01	0.079400	8.56e-01
GO:1990138 neuron projection extension	10	6.64e-01	-0.079400	8.96e-01
GO:0002053 positive regulation of mesenchymal cell proliferation	10	6.64e-01	0.079300	8.96e-01
GO:0016192 vesicle-mediated transport	101	1.70e-01	-0.079100	5.62e-01
GO:0051015 actin filament binding	123	1.31e-01	-0.078900	4.89e-01
GO:0043588 skin development	24	5.04e-01	-0.078900	8.34e-01
GO:0043296 apical junction complex	11	6.51e-01	0.078700	8.93e-01
GO:0042391 regulation of membrane potential	13	6.24e-01	-0.078600	8.88e-01
GO:0005004 GPI-linked ephrin receptor activity	12	6.37e-01	0.078600	8.88e-01
GO:0005011 macrophage colony-stimulating factor receptor activity	12	6.37e-01	0.078600	8.88e-01
GO:0005018 platelet-derived growth factor alpha-receptor activity	12	6.37e-01	0.078600	8.88e-01
GO:0005020 stem cell factor receptor activity	12	6.37e-01	0.078600	8.88e-01
GO:0008288 boss receptor activity	12	6.37e-01	0.078600	8.88e-01
GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway	12	6.37e-01	0.078600	8.88e-01
GO:0036323 vascular endothelial growth factor receptor-1 signaling pathway	12	6.37e-01	0.078600	8.88e-01
GO:0036332 placental growth factor receptor activity	12	6.37e-01	0.078600	8.88e-01
GO:0038145 macrophage colony-stimulating factor signaling pathway	12	6.37e-01	0.078600	8.88e-01
GO:0060175 brain-derived neurotrophic factor receptor activity	12	6.37e-01	0.078600	8.88e-01
GO:0007030 Golgi organization	64	2.79e-01	-0.078400	6.95e-01
GO:0016607 nuclear speck	242	3.68e-02	0.078100	2.83e-01
GO:0007281 germ cell development	14	6.13e-01	-0.078100	8.82e-01
GO:0006302 double-strand break repair	45	3.67e-01	0.077700	7.52e-01
GO:0045211 postsynaptic membrane	57	3.10e-01	0.077700	7.15e-01
GO:0001569 branching involved in blood vessel morphogenesis	15	6.02e-01	-0.077700	8.79e-01
GO:0030276 clathrin binding	17	5.80e-01	0.077600	8.75e-01
GO:0007420 brain development	79	2.34e-01	0.077500	6.49e-01
GO:0098609 cell-cell adhesion	86	2.15e-01	0.077500	6.27e-01
GO:0001756 somitogenesis	24	5.12e-01	-0.077400	8.38e-01
GO:0030897 HOPS complex	10	6.72e-01	-0.077400	8.99e-01
GO:0031369 translation initiation factor binding	12	6.43e-01	0.077300	8.89e-01
GO:0045893 positive regulation of DNA-templated transcription	224	4.85e-02	0.076700	3.27e-01
GO:0031490 chromatin DNA binding	41	3.97e-01	0.076600	7.73e-01
GO:0030331 nuclear estrogen receptor binding	20	5.54e-01	0.076500	8.67e-01
GO:0046540 U4/U6 x U5 tri-snRNP complex	23	5.26e-01	-0.076400	8.47e-01
GO:0071560 cellular response to transforming growth factor beta stimulus	16	5.97e-01	0.076300	8.79e-01
GO:0016020 membrane	959	7.70e-05	-0.076300	9.11e-03
GO:0050673 epithelial cell proliferation	19	5.65e-01	-0.076300	8.69e-01
GO:0005654 nucleoplasm	1529	1.03e-06	0.076200	3.67e-04
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway	13	6.34e-01	-0.076200	8.88e-01
GO:0005164 tumor necrosis factor receptor binding	13	6.35e-01	-0.076100	8.88e-01
GO:0120020 cholesterol transfer activity	12	6.49e-01	-0.075900	8.92e-01
GO:0060349 bone morphogenesis	11	6.63e-01	0.075900	8.96e-01
GO:0001223 transcription coactivator binding	21	5.47e-01	0.075900	8.62e-01
GO:0051289 protein homotetramerization	36	4.31e-01	0.075800	7.89e-01
GO:0071363 cellular response to growth factor stimulus	19	5.68e-01	0.075700	8.70e-01
GO:0030018 Z disc	51	3.53e-01	0.075300	7.49e-01
GO:0051497 negative regulation of stress fiber assembly	18	5.81e-01	0.075200	8.75e-01
GO:0001822 kidney development	51	3.54e-01	-0.075100	7.49e-01
GO:0005874 microtubule	132	1.37e-01	0.075000	5.04e-01
GO:0038202 TORC1 signaling	12	6.54e-01	0.074700	8.95e-01
GO:0030127 COPII vesicle coat	10	6.84e-01	-0.074400	9.07e-01
GO:0019882 antigen processing and presentation	11	6.71e-01	-0.074000	8.99e-01
GO:0098655 monoatomic cation transmembrane transport	14	6.32e-01	0.073900	8.88e-01
GO:0005007 fibroblast growth factor receptor activity	13	6.45e-01	0.073900	8.90e-01
GO:0098793 presynapse	64	3.08e-01	0.073800	7.13e-01
GO:0043015 gamma-tubulin binding	21	5.59e-01	0.073700	8.69e-01
GO:0008203 cholesterol metabolic process	28	5.00e-01	0.073700	8.34e-01
GO:0005506 iron ion binding	63	3.12e-01	0.073700	7.16e-01
GO:0005794 Golgi apparatus	471	6.42e-03	-0.073700	1.28e-01
GO:0008277 regulation of G protein-coupled receptor signaling pathway	16	6.10e-01	-0.073700	8.80e-01
GO:0008286 insulin receptor signaling pathway	49	3.74e-01	-0.073500	7.57e-01
GO:0032735 positive regulation of interleukin-12 production	12	6.60e-01	0.073400	8.96e-01
GO:0005783 endoplasmic reticulum	434	9.10e-03	-0.073400	1.52e-01
GO:0010839 negative regulation of keratinocyte proliferation	14	6.35e-01	-0.073400	8.88e-01
GO:0042098 T cell proliferation	16	6.12e-01	-0.073200	8.82e-01
GO:0004842 ubiquitin-protein transferase activity	66	3.05e-01	0.073100	7.13e-01
GO:0030057 desmosome	13	6.49e-01	-0.072900	8.92e-01
GO:0042733 embryonic digit morphogenesis	29	4.98e-01	-0.072800	8.34e-01
GO:0038191 neuropilin binding	10	6.92e-01	-0.072400	9.09e-01
GO:0004879 nuclear receptor activity	38	4.43e-01	-0.072000	7.96e-01
GO:0010508 positive regulation of autophagy	39	4.38e-01	-0.071900	7.91e-01
GO:0071539 protein localization to centrosome	20	5.79e-01	0.071800	8.75e-01
GO:1905564 positive regulation of vascular endothelial cell proliferation	10	6.95e-01	0.071700	9.11e-01
GO:0007015 actin filament organization	73	2.91e-01	-0.071500	7.08e-01
GO:0009792 embryo development ending in birth or egg hatching	10	6.97e-01	0.071200	9.12e-01
GO:0030175 filopodium	29	5.07e-01	-0.071100	8.36e-01
GO:0030134 COPII-coated ER to Golgi transport vesicle	22	5.65e-01	-0.070900	8.69e-01
GO:0055085 transmembrane transport	88	2.51e-01	0.070900	6.67e-01
GO:0000423 mitophagy	31	4.95e-01	-0.070800	8.34e-01
GO:0016604 nuclear body	172	1.10e-01	0.070700	4.53e-01
GO:0032755 positive regulation of interleukin-6 production	31	4.96e-01	0.070700	8.34e-01
GO:0035267 NuA4 histone acetyltransferase complex	18	6.04e-01	0.070600	8.79e-01
GO:0043531 ADP binding	21	5.76e-01	-0.070400	8.75e-01
GO:0007040 lysosome organization	33	4.85e-01	-0.070300	8.25e-01
GO:0008584 male gonad development	27	5.28e-01	0.070100	8.49e-01
GO:0010506 regulation of autophagy	26	5.37e-01	0.070000	8.54e-01
GO:0003924 GTPase activity	177	1.10e-01	-0.069700	4.53e-01
GO:0050766 positive regulation of phagocytosis	14	6.52e-01	-0.069700	8.93e-01
GO:0006355 regulation of DNA-templated transcription	160	1.29e-01	0.069700	4.85e-01
GO:0032418 lysosome localization	23	5.63e-01	0.069600	8.69e-01
GO:0061025 membrane fusion	21	5.82e-01	-0.069400	8.75e-01
GO:0008201 heparin binding	57	3.66e-01	-0.069300	7.52e-01
GO:0006633 fatty acid biosynthetic process	22	5.74e-01	-0.069200	8.75e-01
GO:0000785 chromatin	242	6.47e-02	0.069100	3.77e-01
GO:0006096 glycolytic process	23	5.66e-01	0.069100	8.69e-01
GO:0015297 antiporter activity	19	6.03e-01	-0.069000	8.79e-01
GO:0006805 xenobiotic metabolic process	17	6.23e-01	-0.068900	8.88e-01
GO:0010761 fibroblast migration	10	7.06e-01	0.068800	9.17e-01
GO:0043001 Golgi to plasma membrane protein transport	21	5.86e-01	0.068700	8.75e-01
GO:0086091 regulation of heart rate by cardiac conduction	21	5.86e-01	-0.068700	8.75e-01
GO:0005245 voltage-gated calcium channel activity	10	7.07e-01	0.068600	9.17e-01
GO:0006493 protein O-linked glycosylation	31	5.09e-01	-0.068600	8.36e-01
GO:0004715 non-membrane spanning protein tyrosine kinase activity	21	5.87e-01	-0.068600	8.75e-01
GO:2000377 regulation of reactive oxygen species metabolic process	10	7.07e-01	-0.068600	9.17e-01
GO:0016477 cell migration	137	1.67e-01	0.068500	5.62e-01
GO:0070131 positive regulation of mitochondrial translation	10	7.08e-01	-0.068300	9.17e-01
GO:0009791 post-embryonic development	37	4.73e-01	-0.068300	8.14e-01
GO:0009615 response to virus	30	5.18e-01	-0.068200	8.41e-01
GO:0007417 central nervous system development	41	4.51e-01	0.068100	8.01e-01
GO:0051301 cell division	144	1.60e-01	0.067900	5.50e-01
GO:0001525 angiogenesis	85	2.80e-01	0.067900	6.96e-01
GO:0046849 bone remodeling	10	7.12e-01	-0.067400	9.17e-01
GO:0005852 eukaryotic translation initiation factor 3 complex	10	7.12e-01	0.067400	9.17e-01
GO:0035091 phosphatidylinositol binding	74	3.17e-01	-0.067300	7.22e-01
GO:0071456 cellular response to hypoxia	33	5.04e-01	-0.067200	8.34e-01
GO:0001618 virus receptor activity	10	7.14e-01	-0.067000	9.17e-01
GO:0017053 transcription repressor complex	34	5.00e-01	0.066900	8.34e-01
GO:0072089 stem cell proliferation	22	5.88e-01	-0.066800	8.75e-01
GO:0001786 phosphatidylserine binding	24	5.72e-01	-0.066700	8.75e-01
GO:0008320 protein transmembrane transporter activity	11	7.02e-01	-0.066700	9.15e-01
GO:0030286 dynein complex	11	7.03e-01	-0.066500	9.16e-01
GO:0000132 establishment of mitotic spindle orientation	26	5.58e-01	0.066300	8.69e-01
GO:0098586 cellular response to virus	22	5.91e-01	-0.066200	8.76e-01
GO:0046513 ceramide biosynthetic process	19	6.19e-01	-0.066000	8.86e-01
GO:0019843 rRNA binding	22	5.94e-01	-0.065700	8.76e-01
GO:0043565 sequence-specific DNA binding	57	3.92e-01	0.065600	7.72e-01
GO:0007416 synapse assembly	26	5.63e-01	0.065600	8.69e-01
GO:0005102 signaling receptor binding	82	3.06e-01	-0.065500	7.13e-01
GO:0015631 tubulin binding	30	5.35e-01	-0.065500	8.54e-01
GO:0019902 phosphatase binding	22	5.95e-01	-0.065400	8.77e-01
GO:0090263 positive regulation of canonical Wnt signaling pathway	62	3.75e-01	-0.065300	7.58e-01
GO:0030178 negative regulation of Wnt signaling pathway	17	6.42e-01	0.065000	8.89e-01
GO:0016757 glycosyltransferase activity	15	6.63e-01	-0.064900	8.96e-01
GO:0019894 kinesin binding	21	6.07e-01	0.064900	8.79e-01
GO:1904294 positive regulation of ERAD pathway	10	7.23e-01	-0.064900	9.21e-01
GO:0030225 macrophage differentiation	11	7.10e-01	-0.064700	9.17e-01
GO:0048870 cell motility	12	6.99e-01	0.064400	9.13e-01
GO:0038023 signaling receptor activity	41	4.76e-01	-0.064300	8.16e-01
GO:0045332 phospholipid translocation	16	6.56e-01	-0.064300	8.95e-01
GO:0035019 somatic stem cell population maintenance	31	5.41e-01	0.063400	8.58e-01
GO:0043235 receptor complex	78	3.34e-01	-0.063400	7.35e-01
GO:0005085 guanyl-nucleotide exchange factor activity	143	1.92e-01	-0.063300	6.01e-01
GO:1990573 potassium ion import across plasma membrane	18	6.42e-01	-0.063300	8.89e-01
GO:0051123 RNA polymerase II preinitiation complex assembly	16	6.61e-01	-0.063200	8.96e-01
GO:0006882 intracellular zinc ion homeostasis	13	6.93e-01	0.063200	9.09e-01
GO:0005886 plasma membrane	1536	4.94e-05	-0.063200	7.31e-03
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding	391	3.32e-02	0.063000	2.75e-01
GO:0002682 regulation of immune system process	10	7.31e-01	-0.062900	9.23e-01
GO:0001558 regulation of cell growth	24	5.94e-01	0.062800	8.76e-01
GO:0098761 cellular response to interleukin-7	10	7.31e-01	-0.062800	9.23e-01
GO:0032012 regulation of ARF protein signal transduction	14	6.88e-01	-0.062000	9.09e-01
GO:0030330 DNA damage response, signal transduction by p53 class mediator	12	7.11e-01	0.061800	9.17e-01
GO:0042472 inner ear morphogenesis	26	5.87e-01	-0.061500	8.75e-01
GO:0016442 RISC complex	11	7.24e-01	-0.061500	9.21e-01
GO:0005637 nuclear inner membrane	24	6.03e-01	0.061300	8.79e-01
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway	14	6.92e-01	-0.061200	9.09e-01
GO:0030139 endocytic vesicle	37	5.20e-01	-0.061200	8.42e-01
GO:0061136 regulation of proteasomal protein catabolic process	11	7.25e-01	0.061200	9.21e-01
GO:0009897 external side of plasma membrane	107	2.75e-01	-0.061200	6.92e-01
GO:0030968 endoplasmic reticulum unfolded protein response	30	5.63e-01	-0.061000	8.69e-01
GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction	35	5.33e-01	-0.060900	8.53e-01
GO:0007204 positive regulation of cytosolic calcium ion concentration	18	6.55e-01	-0.060900	8.95e-01
GO:0030100 regulation of endocytosis	12	7.16e-01	-0.060800	9.18e-01
GO:0006368 transcription elongation by RNA polymerase II	24	6.07e-01	0.060700	8.79e-01
GO:0099175 regulation of postsynapse organization	19	6.47e-01	-0.060600	8.92e-01
GO:0051219 phosphoprotein binding	20	6.40e-01	-0.060500	8.88e-01
GO:0071108 protein K48-linked deubiquitination	15	6.85e-01	-0.060500	9.08e-01
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	17	6.67e-01	0.060300	8.97e-01
GO:0032154 cleavage furrow	28	5.82e-01	-0.060100	8.75e-01
GO:0045824 negative regulation of innate immune response	16	6.77e-01	0.060100	9.05e-01
GO:0042734 presynaptic membrane	38	5.23e-01	-0.060000	8.44e-01
GO:0030177 positive regulation of Wnt signaling pathway	18	6.62e-01	-0.059500	8.96e-01
GO:0045665 negative regulation of neuron differentiation	25	6.07e-01	-0.059500	8.79e-01
GO:0006289 nucleotide-excision repair	22	6.30e-01	-0.059400	8.88e-01
GO:0001958 endochondral ossification	15	6.91e-01	-0.059300	9.09e-01
GO:0010468 regulation of gene expression	58	4.36e-01	-0.059200	7.91e-01
GO:0098982 GABA-ergic synapse	29	5.82e-01	-0.059100	8.75e-01
GO:0007369 gastrulation	10	7.49e-01	0.058500	9.30e-01
GO:0003725 double-stranded RNA binding	44	5.03e-01	0.058400	8.34e-01
GO:0005507 copper ion binding	24	6.21e-01	-0.058300	8.87e-01
GO:0019933 cAMP-mediated signaling	13	7.17e-01	-0.058200	9.19e-01
GO:0004713 protein tyrosine kinase activity	35	5.52e-01	0.058100	8.67e-01
GO:0009410 response to xenobiotic stimulus	48	4.87e-01	-0.058000	8.27e-01
GO:0019706 protein-cysteine S-palmitoyltransferase activity	17	6.79e-01	-0.058000	9.05e-01
GO:0030514 negative regulation of BMP signaling pathway	26	6.10e-01	0.057800	8.80e-01
GO:0044297 cell body	26	6.10e-01	0.057800	8.80e-01
GO:0006954 inflammatory response	82	3.66e-01	-0.057800	7.52e-01
GO:0000956 nuclear-transcribed mRNA catabolic process	12	7.29e-01	0.057700	9.23e-01
GO:0005776 autophagosome	41	5.26e-01	-0.057300	8.47e-01
GO:0044458 motile cilium assembly	12	7.32e-01	0.057100	9.23e-01
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation	30	5.89e-01	0.057000	8.76e-01
GO:0006612 protein targeting to membrane	24	6.29e-01	0.056900	8.88e-01
GO:0050870 positive regulation of T cell activation	14	7.12e-01	0.056900	9.17e-01
GO:0051604 protein maturation	20	6.60e-01	0.056800	8.96e-01
GO:0043025 neuronal cell body	86	3.64e-01	-0.056700	7.52e-01
GO:0007517 muscle organ development	12	7.35e-01	-0.056400	9.24e-01
GO:0019899 enzyme binding	109	3.11e-01	0.056200	7.16e-01
GO:0042470 melanosome	28	6.07e-01	-0.056200	8.79e-01
GO:0070527 platelet aggregation	16	6.97e-01	-0.056200	9.12e-01
GO:0043204 perikaryon	35	5.67e-01	-0.056000	8.69e-01
GO:0046677 response to antibiotic	13	7.27e-01	-0.055900	9.21e-01
GO:0031210 phosphatidylcholine binding	17	6.90e-01	-0.055800	9.09e-01
GO:0001678 intracellular glucose homeostasis	17	6.91e-01	-0.055600	9.09e-01
GO:0016363 nuclear matrix	46	5.16e-01	0.055400	8.41e-01
GO:0042307 positive regulation of protein import into nucleus	24	6.39e-01	0.055400	8.88e-01
GO:0030234 enzyme regulator activity	15	7.11e-01	-0.055300	9.17e-01
GO:0007052 mitotic spindle organization	33	5.83e-01	0.055300	8.75e-01
GO:0007411 axon guidance	80	3.94e-01	0.055200	7.72e-01
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific	180	2.02e-01	0.055200	6.10e-01
GO:0051259 protein complex oligomerization	14	7.21e-01	0.055100	9.20e-01
GO:0005881 cytoplasmic microtubule	30	6.01e-01	-0.055100	8.79e-01
GO:0006909 phagocytosis	23	6.48e-01	-0.055100	8.92e-01
GO:0033192 calmodulin-dependent protein phosphatase activity	16	7.04e-01	-0.054900	9.17e-01
GO:0016342 catenin complex	14	7.23e-01	-0.054800	9.21e-01
GO:0006346 DNA methylation-dependent constitutive heterochromatin formation	10	7.65e-01	0.054700	9.39e-01
GO:0001676 long-chain fatty acid metabolic process	11	7.54e-01	0.054700	9.35e-01
GO:0061077 chaperone-mediated protein folding	16	7.05e-01	0.054700	9.17e-01
GO:0046907 intracellular transport	14	7.25e-01	-0.054300	9.21e-01
GO:0060382 regulation of DNA strand elongation	10	7.67e-01	0.054100	9.39e-01
GO:0043124 negative regulation of canonical NF-kappaB signal transduction	35	5.80e-01	0.054100	8.75e-01
GO:0051865 protein autoubiquitination	40	5.54e-01	0.054100	8.67e-01
GO:1904262 negative regulation of TORC1 signaling	28	6.21e-01	-0.054000	8.87e-01
GO:0007520 myoblast fusion	10	7.68e-01	0.053800	9.39e-01
GO:0004725 protein tyrosine phosphatase activity	44	5.37e-01	0.053800	8.55e-01
GO:0030163 protein catabolic process	31	6.05e-01	0.053700	8.79e-01
GO:0000165 MAPK cascade	46	5.29e-01	0.053700	8.49e-01
GO:0071526 semaphorin-plexin signaling pathway	25	6.42e-01	0.053700	8.89e-01
GO:0071230 cellular response to amino acid stimulus	29	6.17e-01	-0.053600	8.85e-01
GO:0035924 cellular response to vascular endothelial growth factor stimulus	16	7.11e-01	0.053600	9.17e-01
GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity	13	7.38e-01	-0.053500	9.24e-01
GO:0008542 visual learning	20	6.79e-01	-0.053500	9.05e-01
GO:0045944 positive regulation of transcription by RNA polymerase II	524	3.75e-02	0.053400	2.86e-01
GO:0008104 protein localization	68	4.47e-01	-0.053300	7.99e-01
GO:0030145 manganese ion binding	45	5.39e-01	-0.052900	8.56e-01
GO:0030332 cyclin binding	20	6.83e-01	0.052700	9.07e-01
GO:0003779 actin binding	142	2.81e-01	-0.052500	6.98e-01
GO:0016251 RNA polymerase II general transcription initiation factor activity	22	6.71e-01	0.052300	8.99e-01
GO:0051087 protein-folding chaperone binding	56	4.99e-01	0.052300	8.34e-01
GO:0051216 cartilage development	21	6.79e-01	0.052200	9.05e-01
GO:0007010 cytoskeleton organization	50	5.24e-01	0.052100	8.46e-01
GO:0097009 energy homeostasis	23	6.67e-01	-0.051900	8.97e-01
GO:0003281 ventricular septum development	14	7.37e-01	0.051800	9.24e-01
GO:1990756 ubiquitin-like ligase-substrate adaptor activity	72	4.48e-01	0.051700	7.99e-01
GO:0097546 ciliary base	16	7.21e-01	0.051600	9.20e-01
GO:0051402 neuron apoptotic process	42	5.64e-01	-0.051500	8.69e-01
GO:0042060 wound healing	28	6.38e-01	0.051400	8.88e-01
GO:0031398 positive regulation of protein ubiquitination	40	5.79e-01	-0.050800	8.75e-01
GO:0071356 cellular response to tumor necrosis factor	37	5.93e-01	0.050800	8.76e-01
GO:0042742 defense response to bacterium	28	6.43e-01	-0.050600	8.89e-01
GO:0051592 response to calcium ion	20	6.96e-01	0.050500	9.11e-01
GO:0070979 protein K11-linked ubiquitination	22	6.84e-01	-0.050200	9.07e-01
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation	14	7.45e-01	0.050100	9.29e-01
GO:0005540 hyaluronic acid binding	13	7.55e-01	0.050100	9.35e-01
GO:0031012 extracellular matrix	90	4.12e-01	-0.050100	7.85e-01
GO:0016328 lateral plasma membrane	24	6.72e-01	-0.050000	8.99e-01
GO:0007265 Ras protein signal transduction	37	5.99e-01	-0.050000	8.79e-01
GO:0016358 dendrite development	19	7.07e-01	0.049800	9.17e-01
GO:1904263 positive regulation of TORC1 signaling	35	6.12e-01	-0.049500	8.82e-01
GO:0001541 ovarian follicle development	19	7.11e-01	0.049000	9.17e-01
GO:0043525 positive regulation of neuron apoptotic process	18	7.19e-01	0.049000	9.20e-01
GO:0031252 cell leading edge	19	7.12e-01	0.049000	9.17e-01
GO:0043425 bHLH transcription factor binding	10	7.89e-01	-0.049000	9.48e-01
GO:0004672 protein kinase activity	64	5.01e-01	-0.048700	8.34e-01
GO:0010629 negative regulation of gene expression	101	3.99e-01	-0.048700	7.74e-01
GO:0007155 cell adhesion	105	3.91e-01	-0.048500	7.72e-01
GO:0061564 axon development	13	7.62e-01	-0.048500	9.39e-01
GO:0007163 establishment or maintenance of cell polarity	13	7.64e-01	-0.048100	9.39e-01
GO:0002020 protease binding	44	5.81e-01	0.048100	8.75e-01
GO:0007032 endosome organization	28	6.60e-01	0.048000	8.96e-01
GO:0045668 negative regulation of osteoblast differentiation	27	6.67e-01	0.047900	8.97e-01
GO:0007026 negative regulation of microtubule depolymerization	17	7.32e-01	0.047900	9.23e-01
GO:0005635 nuclear envelope	77	4.69e-01	-0.047800	8.14e-01
GO:0051019 mitogen-activated protein kinase binding	11	7.84e-01	-0.047800	9.47e-01
GO:0003774 cytoskeletal motor activity	14	7.58e-01	-0.047600	9.38e-01
GO:0006486 protein glycosylation	45	5.81e-01	-0.047500	8.75e-01
GO:0060976 coronary vasculature development	17	7.35e-01	0.047500	9.24e-01
GO:0046983 protein dimerization activity	69	4.96e-01	0.047500	8.34e-01
GO:0032922 circadian regulation of gene expression	34	6.32e-01	0.047400	8.88e-01
GO:0030010 establishment of cell polarity	18	7.28e-01	-0.047400	9.22e-01
GO:0035591 signaling adaptor activity	40	6.05e-01	-0.047300	8.79e-01
GO:0001819 positive regulation of cytokine production	13	7.68e-01	0.047300	9.39e-01
GO:0016042 lipid catabolic process	29	6.61e-01	-0.047100	8.96e-01
GO:0006487 protein N-linked glycosylation	30	6.56e-01	-0.047000	8.95e-01
GO:0008285 negative regulation of cell population proliferation	118	3.79e-01	-0.047000	7.62e-01
GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity	34	6.36e-01	-0.046900	8.88e-01
GO:0060291 long-term synaptic potentiation	11	7.88e-01	-0.046900	9.48e-01
GO:0000209 protein polyubiquitination	78	4.75e-01	-0.046800	8.15e-01
GO:0048015 phosphatidylinositol-mediated signaling	18	7.32e-01	0.046700	9.23e-01
GO:0006006 glucose metabolic process	26	6.81e-01	-0.046600	9.05e-01
GO:0007623 circadian rhythm	18	7.32e-01	0.046600	9.23e-01
GO:0030246 carbohydrate binding	41	6.07e-01	-0.046500	8.79e-01
GO:0007528 neuromuscular junction development	14	7.64e-01	0.046400	9.39e-01
GO:0051403 stress-activated MAPK cascade	12	7.82e-01	-0.046200	9.46e-01
GO:0007405 neuroblast proliferation	21	7.14e-01	0.046200	9.17e-01
GO:0001784 phosphotyrosine residue binding	27	6.79e-01	0.046100	9.05e-01
GO:0016592 mediator complex	29	6.68e-01	0.046000	8.99e-01
GO:0042277 peptide binding	10	8.02e-01	-0.045900	9.51e-01
GO:0006511 ubiquitin-dependent protein catabolic process	117	3.92e-01	-0.045900	7.72e-01
GO:0005856 cytoskeleton	174	2.99e-01	-0.045800	7.11e-01
GO:0034063 stress granule assembly	20	7.24e-01	0.045700	9.21e-01
GO:0048384 retinoic acid receptor signaling pathway	11	7.94e-01	0.045500	9.51e-01
GO:0001732 formation of cytoplasmic translation initiation complex	12	7.85e-01	0.045500	9.47e-01
GO:0000139 Golgi membrane	264	2.05e-01	-0.045500	6.13e-01
GO:0050821 protein stabilization	109	4.13e-01	0.045400	7.85e-01
GO:0097190 apoptotic signaling pathway	20	7.26e-01	0.045300	9.21e-01
GO:0031122 cytoplasmic microtubule organization	27	6.88e-01	0.044600	9.09e-01
GO:0000122 negative regulation of transcription by RNA polymerase II	394	1.31e-01	0.044600	4.88e-01
GO:0006893 Golgi to plasma membrane transport	19	7.37e-01	0.044500	9.24e-01
GO:0014704 intercalated disc	14	7.73e-01	-0.044500	9.42e-01
GO:0097194 execution phase of apoptosis	10	8.08e-01	0.044300	9.51e-01
GO:0060395 SMAD protein signal transduction	14	7.74e-01	-0.044300	9.42e-01
GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity	10	8.08e-01	-0.044300	9.51e-01
GO:0051457 maintenance of protein location in nucleus	10	8.09e-01	-0.044100	9.51e-01
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway	11	8.01e-01	0.043900	9.51e-01
GO:0034599 cellular response to oxidative stress	44	6.15e-01	0.043900	8.83e-01
GO:0140416 transcription regulator inhibitor activity	12	7.94e-01	-0.043600	9.51e-01
GO:0001725 stress fiber	42	6.26e-01	0.043500	8.88e-01
GO:0007286 spermatid development	25	7.10e-01	-0.043000	9.17e-01
GO:0030017 sarcomere	12	7.97e-01	-0.042900	9.51e-01
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process	43	6.29e-01	-0.042600	8.88e-01
GO:0005882 intermediate filament	21	7.36e-01	-0.042500	9.24e-01
GO:0106310 protein serine kinase activity	38	6.51e-01	0.042400	8.93e-01
GO:0070588 calcium ion transmembrane transport	43	6.35e-01	0.041900	8.88e-01
GO:0034198 cellular response to amino acid starvation	31	6.87e-01	-0.041900	9.09e-01
GO:0051642 centrosome localization	13	7.94e-01	-0.041800	9.51e-01
GO:0070840 dynein complex binding	12	8.02e-01	-0.041800	9.51e-01
GO:0001736 establishment of planar polarity	11	8.11e-01	-0.041700	9.51e-01
GO:0008017 microtubule binding	153	3.75e-01	-0.041600	7.58e-01
GO:0009954 proximal/distal pattern formation	14	7.88e-01	0.041500	9.48e-01
GO:0006325 chromatin organization	66	5.60e-01	0.041500	8.69e-01
GO:0007601 visual perception	37	6.63e-01	-0.041500	8.96e-01
GO:0005254 chloride channel activity	18	7.61e-01	0.041400	9.39e-01
GO:0043231 intracellular membrane-bounded organelle	117	4.44e-01	0.041000	7.97e-01
GO:0035613 RNA stem-loop binding	11	8.14e-01	-0.041000	9.52e-01
GO:0030199 collagen fibril organization	31	6.93e-01	-0.040900	9.09e-01
GO:0045880 positive regulation of smoothened signaling pathway	22	7.40e-01	-0.040800	9.25e-01
GO:0004721 phosphoprotein phosphatase activity	21	7.48e-01	0.040600	9.29e-01
GO:0060038 cardiac muscle cell proliferation	12	8.09e-01	-0.040400	9.51e-01
GO:0005759 mitochondrial matrix	120	4.48e-01	-0.040100	7.99e-01
GO:0071364 cellular response to epidermal growth factor stimulus	19	7.63e-01	-0.040000	9.39e-01
GO:0032543 mitochondrial translation	22	7.46e-01	0.039900	9.29e-01
GO:0005912 adherens junction	72	5.59e-01	-0.039800	8.69e-01
GO:0007005 mitochondrion organization	61	5.93e-01	-0.039600	8.76e-01
GO:0030215 semaphorin receptor binding	13	8.05e-01	-0.039600	9.51e-01
GO:0045087 innate immune response	82	5.36e-01	-0.039600	8.54e-01
GO:0098978 glutamatergic synapse	232	3.01e-01	-0.039500	7.13e-01
GO:0043122 regulation of canonical NF-kappaB signal transduction	17	7.78e-01	-0.039500	9.44e-01
GO:0060170 ciliary membrane	19	7.66e-01	-0.039400	9.39e-01
GO:0048706 embryonic skeletal system development	16	7.85e-01	0.039400	9.47e-01
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors	18	7.74e-01	0.039100	9.42e-01
GO:0046872 metal ion binding	878	5.21e-02	0.039100	3.34e-01
GO:0016324 apical plasma membrane	123	4.56e-01	-0.039000	8.01e-01
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity	15	7.96e-01	0.038600	9.51e-01
GO:0031418 L-ascorbic acid binding	14	8.04e-01	0.038300	9.51e-01
GO:1990830 cellular response to leukemia inhibitory factor	67	5.89e-01	0.038200	8.76e-01
GO:0005634 nucleus	2133	4.92e-03	0.038100	1.09e-01
GO:0051290 protein heterotetramerization	10	8.35e-01	-0.038000	9.64e-01
GO:0006672 ceramide metabolic process	10	8.35e-01	-0.038000	9.64e-01
GO:0045599 negative regulation of fat cell differentiation	19	7.75e-01	-0.037900	9.42e-01
GO:0005009 insulin receptor activity	14	8.06e-01	-0.037800	9.51e-01
GO:0005778 peroxisomal membrane	27	7.34e-01	-0.037800	9.24e-01
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway	19	7.76e-01	-0.037700	9.43e-01
GO:0044183 protein folding chaperone	21	7.67e-01	0.037400	9.39e-01
GO:0042752 regulation of circadian rhythm	27	7.36e-01	0.037400	9.24e-01
GO:0043495 protein-membrane adaptor activity	17	7.90e-01	0.037400	9.48e-01
GO:0045787 positive regulation of cell cycle	13	8.16e-01	-0.037300	9.53e-01
GO:0035869 ciliary transition zone	22	7.62e-01	0.037300	9.39e-01
GO:0071320 cellular response to cAMP	19	7.80e-01	0.037000	9.45e-01
GO:0035082 axoneme assembly	10	8.40e-01	-0.036900	9.64e-01
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	28	7.37e-01	-0.036700	9.24e-01
GO:0001669 acrosomal vesicle	27	7.41e-01	-0.036700	9.26e-01
GO:0004402 histone acetyltransferase activity	11	8.33e-01	-0.036700	9.64e-01
GO:0000151 ubiquitin ligase complex	48	6.60e-01	-0.036700	8.96e-01
GO:0045814 negative regulation of gene expression, epigenetic	16	8.01e-01	0.036500	9.51e-01
GO:0006874 intracellular calcium ion homeostasis	38	6.98e-01	0.036400	9.12e-01
GO:0050840 extracellular matrix binding	17	7.95e-01	0.036400	9.51e-01
GO:0007224 smoothened signaling pathway	49	6.61e-01	-0.036200	8.96e-01
GO:0005819 spindle	54	6.45e-01	0.036200	8.90e-01
GO:0035556 intracellular signal transduction	185	3.98e-01	-0.036100	7.74e-01
GO:0007605 sensory perception of sound	56	6.40e-01	-0.036100	8.89e-01
GO:0043524 negative regulation of neuron apoptotic process	51	6.56e-01	-0.036100	8.95e-01
GO:0051649 establishment of localization in cell	41	6.91e-01	0.035900	9.09e-01
GO:0002931 response to ischemia	10	8.44e-01	-0.035800	9.64e-01
GO:0060218 hematopoietic stem cell differentiation	11	8.37e-01	0.035800	9.64e-01
GO:0043679 axon terminus	17	7.99e-01	-0.035700	9.51e-01
GO:0044877 protein-containing complex binding	104	5.30e-01	0.035700	8.49e-01
GO:0055037 recycling endosome	55	6.48e-01	0.035600	8.92e-01
GO:0060236 regulation of mitotic spindle organization	12	8.31e-01	0.035500	9.64e-01
GO:0045892 negative regulation of DNA-templated transcription	174	4.20e-01	0.035500	7.87e-01
GO:0061024 membrane organization	13	8.25e-01	0.035500	9.60e-01
GO:0006508 proteolysis	174	4.22e-01	-0.035400	7.88e-01
GO:0098685 Schaffer collateral - CA1 synapse	42	6.93e-01	-0.035200	9.09e-01
GO:0060412 ventricular septum morphogenesis	17	8.03e-01	-0.034900	9.51e-01
GO:0042803 protein homodimerization activity	371	2.51e-01	-0.034900	6.67e-01
GO:0042147 retrograde transport, endosome to Golgi	50	6.71e-01	-0.034800	8.99e-01
GO:0005515 protein binding	92	5.66e-01	-0.034600	8.69e-01
GO:0042149 cellular response to glucose starvation	29	7.48e-01	0.034500	9.29e-01
GO:0140297 DNA-binding transcription factor binding	72	6.15e-01	-0.034300	8.83e-01
GO:0016226 iron-sulfur cluster assembly	17	8.07e-01	-0.034300	9.51e-01
GO:0005200 structural constituent of cytoskeleton	28	7.55e-01	-0.034200	9.35e-01
GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels	16	8.13e-01	0.034100	9.52e-01
GO:0005911 cell-cell junction	79	6.02e-01	-0.034000	8.79e-01
GO:0034394 protein localization to cell surface	17	8.08e-01	-0.034000	9.51e-01
GO:0004222 metalloendopeptidase activity	50	6.80e-01	-0.033700	9.05e-01
GO:0007507 heart development	79	6.06e-01	0.033600	8.79e-01
GO:0034644 cellular response to UV	32	7.43e-01	0.033500	9.26e-01
GO:0015026 coreceptor activity	13	8.35e-01	-0.033300	9.64e-01
GO:0030316 osteoclast differentiation	28	7.63e-01	0.032900	9.39e-01
GO:0008198 ferrous iron binding	12	8.44e-01	0.032900	9.64e-01
GO:0015031 protein transport	174	4.56e-01	-0.032800	8.01e-01
GO:0016925 protein sumoylation	19	8.05e-01	0.032700	9.51e-01
GO:0048704 embryonic skeletal system morphogenesis	18	8.10e-01	0.032700	9.51e-01
GO:0035791 platelet-derived growth factor receptor-beta signaling pathway	15	8.26e-01	0.032700	9.61e-01
GO:0097550 transcription preinitiation complex	12	8.45e-01	-0.032700	9.64e-01
GO:0008083 growth factor activity	41	7.20e-01	0.032300	9.20e-01
GO:0009953 dorsal/ventral pattern formation	16	8.23e-01	0.032300	9.59e-01
GO:0030374 nuclear receptor coactivator activity	31	7.56e-01	0.032300	9.36e-01
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific	113	5.55e-01	-0.032200	8.67e-01
GO:0030855 epithelial cell differentiation	28	7.68e-01	-0.032200	9.39e-01
GO:0006915 apoptotic process	135	5.20e-01	-0.032100	8.42e-01
GO:0060090 molecular adaptor activity	75	6.33e-01	-0.031900	8.88e-01
GO:0008593 regulation of Notch signaling pathway	10	8.61e-01	0.031900	9.65e-01
GO:0009952 anterior/posterior pattern specification	42	7.21e-01	0.031900	9.20e-01
GO:0001675 acrosome assembly	11	8.55e-01	-0.031900	9.64e-01
GO:0006357 regulation of transcription by RNA polymerase II	547	2.07e-01	0.031800	6.16e-01
GO:0005006 epidermal growth factor receptor activity	14	8.37e-01	0.031700	9.64e-01
GO:0005884 actin filament	43	7.20e-01	0.031600	9.20e-01
GO:0043130 ubiquitin binding	61	6.70e-01	0.031500	8.99e-01
GO:0005795 Golgi stack	19	8.12e-01	0.031500	9.52e-01
GO:0017148 negative regulation of translation	44	7.18e-01	0.031500	9.20e-01
GO:0046330 positive regulation of JNK cascade	37	7.42e-01	0.031300	9.26e-01
GO:0017166 vinculin binding	10	8.65e-01	-0.031100	9.68e-01
GO:1990782 protein tyrosine kinase binding	15	8.37e-01	-0.030800	9.64e-01
GO:0030141 secretory granule	19	8.17e-01	-0.030700	9.54e-01
GO:0009898 cytoplasmic side of plasma membrane	48	7.13e-01	-0.030700	9.17e-01
GO:0009986 cell surface	180	4.82e-01	-0.030500	8.22e-01
GO:0004857 enzyme inhibitor activity	13	8.50e-01	0.030300	9.64e-01
GO:0007409 axonogenesis	40	7.45e-01	-0.029800	9.28e-01
GO:0043123 positive regulation of canonical NF-kappaB signal transduction	75	6.58e-01	-0.029500	8.96e-01
GO:0097110 scaffold protein binding	28	7.89e-01	-0.029300	9.48e-01
GO:0007099 centriole replication	13	8.55e-01	0.029300	9.64e-01
GO:0007268 chemical synaptic transmission	32	7.75e-01	0.029200	9.42e-01
GO:0007254 JNK cascade	25	8.01e-01	-0.029100	9.51e-01
GO:0060586 multicellular organismal-level iron ion homeostasis	15	8.50e-01	0.028300	9.64e-01
GO:0035249 synaptic transmission, glutamatergic	17	8.41e-01	-0.028200	9.64e-01
GO:0030971 receptor tyrosine kinase binding	32	7.83e-01	0.028200	9.47e-01
GO:0008284 positive regulation of cell population proliferation	157	5.46e-01	0.028000	8.60e-01
GO:0035264 multicellular organism growth	67	6.93e-01	0.027900	9.09e-01
GO:0000712 resolution of meiotic recombination intermediates	14	8.57e-01	-0.027900	9.64e-01
GO:0005739 mitochondrion	611	2.44e-01	-0.027800	6.60e-01
GO:0007020 microtubule nucleation	14	8.58e-01	0.027500	9.64e-01
GO:0098839 postsynaptic density membrane	35	7.78e-01	0.027500	9.44e-01
GO:0030206 chondroitin sulfate biosynthetic process	11	8.75e-01	0.027400	9.70e-01
GO:0004679 AMP-activated protein kinase activity	32	7.89e-01	-0.027400	9.48e-01
GO:0005929 cilium	78	6.78e-01	-0.027300	9.05e-01
GO:0001530 lipopolysaccharide binding	11	8.76e-01	0.027200	9.70e-01
GO:0030742 GTP-dependent protein binding	13	8.65e-01	-0.027100	9.68e-01
GO:0036211 protein modification process	16	8.52e-01	-0.027000	9.64e-01
GO:0071005 U2-type precatalytic spliceosome	31	7.96e-01	0.026900	9.51e-01
GO:1990837 sequence-specific double-stranded DNA binding	47	7.52e-01	-0.026700	9.33e-01
GO:0001707 mesoderm formation	15	8.58e-01	-0.026600	9.64e-01
GO:0101031 protein folding chaperone complex	18	8.45e-01	-0.026600	9.64e-01
GO:0009925 basal plasma membrane	12	8.73e-01	-0.026600	9.70e-01
GO:0051117 ATPase binding	44	7.61e-01	-0.026500	9.39e-01
GO:0050919 negative chemotaxis	23	8.26e-01	-0.026400	9.61e-01
GO:0004711 ribosomal protein S6 kinase activity	32	8.00e-01	-0.025900	9.51e-01
GO:0006816 calcium ion transport	19	8.46e-01	-0.025800	9.64e-01
GO:0001938 positive regulation of endothelial cell proliferation	22	8.35e-01	0.025700	9.64e-01
GO:0031547 brain-derived neurotrophic factor receptor signaling pathway	14	8.69e-01	0.025600	9.69e-01
GO:0005669 transcription factor TFIID complex	22	8.37e-01	-0.025400	9.64e-01
GO:0007160 cell-matrix adhesion	40	7.82e-01	-0.025300	9.46e-01
GO:0003824 catalytic activity	11	8.85e-01	0.025200	9.74e-01
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific	346	4.24e-01	0.025100	7.88e-01
GO:0008270 zinc ion binding	399	3.93e-01	-0.025000	7.72e-01
GO:0035331 negative regulation of hippo signaling	18	8.57e-01	0.024500	9.64e-01
GO:0005112 Notch binding	13	8.79e-01	0.024400	9.73e-01
GO:0061744 motor behavior	16	8.67e-01	-0.024300	9.69e-01
GO:0046982 protein heterodimerization activity	130	6.35e-01	-0.024100	8.88e-01
GO:0030659 cytoplasmic vesicle membrane	43	7.84e-01	0.024100	9.47e-01
GO:0043066 negative regulation of apoptotic process	150	6.11e-01	-0.024100	8.81e-01
GO:0016601 Rac protein signal transduction	17	8.65e-01	0.023900	9.68e-01
GO:0005813 centrosome	343	4.53e-01	0.023700	8.01e-01
GO:0004888 transmembrane signaling receptor activity	22	8.48e-01	-0.023600	9.64e-01
GO:0072542 protein phosphatase activator activity	10	8.97e-01	-0.023600	9.79e-01
GO:0048278 vesicle docking	13	8.84e-01	-0.023500	9.74e-01
GO:0001540 amyloid-beta binding	28	8.30e-01	0.023400	9.64e-01
GO:0030901 midbrain development	11	8.93e-01	-0.023400	9.79e-01
GO:0141198 protein branched polyubiquitination	13	8.85e-01	0.023300	9.74e-01
GO:0140374 antiviral innate immune response	20	8.57e-01	-0.023300	9.64e-01
GO:0006783 heme biosynthetic process	10	8.99e-01	0.023200	9.79e-01
GO:0048487 beta-tubulin binding	22	8.51e-01	-0.023200	9.64e-01
GO:0005829 cytosol	2018	9.49e-02	0.023100	4.35e-01
GO:0030424 axon	120	6.64e-01	-0.023000	8.96e-01
GO:0007173 epidermal growth factor receptor signaling pathway	38	8.07e-01	-0.022900	9.51e-01
GO:0016922 nuclear receptor binding	21	8.56e-01	-0.022900	9.64e-01
GO:0055038 recycling endosome membrane	43	7.96e-01	0.022800	9.51e-01
GO:0007214 gamma-aminobutyric acid signaling pathway	11	8.96e-01	0.022700	9.79e-01
GO:0097602 cullin family protein binding	16	8.75e-01	-0.022700	9.70e-01
GO:0035064 methylated histone binding	42	8.03e-01	-0.022300	9.51e-01
GO:0001764 neuron migration	39	8.10e-01	0.022200	9.51e-01
GO:0015629 actin cytoskeleton	115	6.81e-01	-0.022200	9.05e-01
GO:0031966 mitochondrial membrane	38	8.13e-01	-0.022100	9.52e-01
GO:0001708 cell fate specification	12	8.95e-01	0.022000	9.79e-01
GO:0045724 positive regulation of cilium assembly	13	8.92e-01	-0.021700	9.79e-01
GO:0090398 cellular senescence	19	8.71e-01	0.021500	9.69e-01
GO:0016605 PML body	61	7.71e-01	0.021500	9.41e-01
GO:0042552 myelination	28	8.44e-01	0.021500	9.64e-01
GO:0005791 rough endoplasmic reticulum	12	8.98e-01	0.021400	9.79e-01
GO:0007266 Rho protein signal transduction	33	8.32e-01	-0.021300	9.64e-01
GO:0070371 ERK1 and ERK2 cascade	20	8.69e-01	0.021300	9.69e-01
GO:0043065 positive regulation of apoptotic process	123	6.85e-01	0.021200	9.07e-01
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT	12	8.99e-01	-0.021100	9.79e-01
GO:0017124 SH3 domain binding	43	8.12e-01	-0.021000	9.51e-01
GO:0005096 GTPase activator activity	153	6.55e-01	0.021000	8.95e-01
GO:0070301 cellular response to hydrogen peroxide	24	8.59e-01	-0.020900	9.64e-01
GO:0016323 basolateral plasma membrane	95	7.27e-01	0.020800	9.21e-01
GO:0030534 adult behavior	10	9.10e-01	-0.020600	9.82e-01
GO:0030890 positive regulation of B cell proliferation	21	8.71e-01	0.020500	9.69e-01
GO:0040029 epigenetic regulation of gene expression	18	8.81e-01	0.020400	9.73e-01
GO:0071168 protein localization to chromatin	17	8.86e-01	-0.020100	9.74e-01
GO:0030674 protein-macromolecule adaptor activity	73	7.67e-01	0.020100	9.39e-01
GO:0035175 histone H3S10 kinase activity	31	8.49e-01	-0.019800	9.64e-01
GO:0072354 histone H3T3 kinase activity	31	8.49e-01	-0.019800	9.64e-01
GO:0004677 DNA-dependent protein kinase activity	31	8.51e-01	0.019500	9.64e-01
GO:0038109 Kit signaling pathway	14	9.00e-01	-0.019500	9.79e-01
GO:0008340 determination of adult lifespan	21	8.78e-01	0.019400	9.72e-01
GO:0090110 COPII-coated vesicle cargo loading	10	9.16e-01	-0.019400	9.85e-01
GO:0031941 filamentous actin	19	8.84e-01	-0.019300	9.74e-01
GO:0007165 signal transduction	265	5.90e-01	-0.019300	8.76e-01
GO:0006955 immune response	41	8.31e-01	-0.019300	9.64e-01
GO:0008360 regulation of cell shape	60	7.97e-01	0.019300	9.51e-01
GO:0000166 nucleotide binding	37	8.40e-01	0.019200	9.64e-01
GO:0003333 amino acid transmembrane transport	10	9.17e-01	-0.019100	9.85e-01
GO:0001501 skeletal system development	34	8.47e-01	0.019100	9.64e-01
GO:0060021 roof of mouth development	35	8.45e-01	0.019100	9.64e-01
GO:0072657 protein localization to membrane	19	8.86e-01	0.019000	9.74e-01
GO:0070971 endoplasmic reticulum exit site	19	8.86e-01	-0.019000	9.74e-01
GO:0070085 glycosylation	14	9.03e-01	0.018900	9.81e-01
GO:0001843 neural tube closure	47	8.23e-01	0.018900	9.59e-01
GO:0043153 entrainment of circadian clock by photoperiod	13	9.07e-01	0.018700	9.82e-01
GO:0032580 Golgi cisterna membrane	27	8.69e-01	-0.018400	9.69e-01
GO:0031463 Cul3-RING ubiquitin ligase complex	42	8.40e-01	-0.018000	9.64e-01
GO:0051260 protein homooligomerization	47	8.33e-01	0.017800	9.64e-01
GO:0032467 positive regulation of cytokinesis	14	9.10e-01	0.017500	9.82e-01
GO:0051607 defense response to virus	56	8.21e-01	-0.017500	9.57e-01
GO:0004197 cysteine-type endopeptidase activity	37	8.54e-01	-0.017500	9.64e-01
GO:0051393 alpha-actinin binding	10	9.24e-01	0.017400	9.89e-01
GO:0097225 sperm midpiece	16	9.05e-01	-0.017300	9.82e-01
GO:0034446 substrate adhesion-dependent cell spreading	35	8.60e-01	-0.017300	9.64e-01
GO:0015914 phospholipid transport	25	8.82e-01	-0.017200	9.74e-01
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process	19	8.97e-01	0.017200	9.79e-01
GO:0050890 cognition	18	9.00e-01	0.017100	9.79e-01
GO:0035329 hippo signaling	18	9.00e-01	-0.017100	9.79e-01
GO:0010628 positive regulation of gene expression	147	7.23e-01	0.016900	9.21e-01
GO:0005802 trans-Golgi network	100	7.71e-01	-0.016900	9.41e-01
GO:0048167 regulation of synaptic plasticity	16	9.09e-01	-0.016500	9.82e-01
GO:0140823 histone H2BS36 kinase activity	31	8.74e-01	-0.016500	9.70e-01
GO:0030335 positive regulation of cell migration	110	7.67e-01	-0.016400	9.39e-01
GO:0007029 endoplasmic reticulum organization	16	9.10e-01	-0.016300	9.82e-01
GO:0032880 regulation of protein localization	41	8.57e-01	0.016200	9.64e-01
GO:0007166 cell surface receptor signaling pathway	40	8.59e-01	-0.016200	9.64e-01
GO:0046034 ATP metabolic process	12	9.24e-01	0.015800	9.89e-01
GO:0005179 hormone activity	12	9.25e-01	0.015800	9.89e-01
GO:0000077 DNA damage checkpoint signaling	26	8.90e-01	-0.015700	9.77e-01
GO:0031526 brush border membrane	12	9.25e-01	0.015700	9.89e-01
GO:0009267 cellular response to starvation	48	8.51e-01	-0.015700	9.64e-01
GO:0016567 protein ubiquitination	155	7.40e-01	-0.015500	9.25e-01
GO:0030425 dendrite	133	7.63e-01	-0.015200	9.39e-01
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle	26	8.95e-01	-0.015000	9.79e-01
GO:0000145 exocyst	12	9.29e-01	-0.015000	9.91e-01
GO:1903078 positive regulation of protein localization to plasma membrane	21	9.06e-01	-0.014900	9.82e-01
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	12	9.29e-01	-0.014800	9.91e-01
GO:0045171 intercellular bridge	55	8.50e-01	0.014800	9.64e-01
GO:0016525 negative regulation of angiogenesis	36	8.80e-01	-0.014600	9.73e-01
GO:0008047 enzyme activator activity	15	9.23e-01	0.014400	9.89e-01
GO:0070161 anchoring junction	18	9.17e-01	0.014200	9.85e-01
GO:0005201 extracellular matrix structural constituent	13	9.31e-01	-0.013900	9.92e-01
GO:0046856 phosphatidylinositol dephosphorylation	26	9.04e-01	-0.013700	9.81e-01
GO:0036503 ERAD pathway	59	8.56e-01	0.013700	9.64e-01
GO:0005789 endoplasmic reticulum membrane	407	6.38e-01	-0.013700	8.88e-01
GO:0005178 integrin binding	66	8.49e-01	0.013600	9.64e-01
GO:0035176 social behavior	16	9.25e-01	0.013600	9.89e-01
GO:0030496 midbody	98	8.18e-01	-0.013500	9.54e-01
GO:0034702 monoatomic ion channel complex	10	9.42e-01	-0.013300	9.97e-01
GO:0048471 perinuclear region of cytoplasm	290	6.98e-01	0.013300	9.12e-01
GO:0000776 kinetochore	90	8.28e-01	-0.013200	9.62e-01
GO:0070403 NAD+ binding	11	9.40e-01	0.013200	9.96e-01
GO:0007613 memory	28	9.05e-01	0.013000	9.82e-01
GO:0010507 negative regulation of autophagy	22	9.16e-01	0.012900	9.85e-01
GO:0001917 photoreceptor inner segment	24	9.14e-01	-0.012800	9.85e-01
GO:0030900 forebrain development	19	9.25e-01	-0.012500	9.89e-01
GO:0005788 endoplasmic reticulum lumen	40	8.91e-01	-0.012500	9.78e-01
GO:0002244 hematopoietic progenitor cell differentiation	34	9.01e-01	0.012300	9.80e-01
GO:0003341 cilium movement	10	9.47e-01	0.012200	9.98e-01
GO:0062023 collagen-containing extracellular matrix	75	8.57e-01	-0.012100	9.64e-01
GO:0050660 flavin adenine dinucleotide binding	32	9.06e-01	-0.012000	9.82e-01
GO:0051131 chaperone-mediated protein complex assembly	14	9.39e-01	0.011800	9.96e-01
GO:0035979 histone H2AXS139 kinase activity	32	9.09e-01	0.011600	9.82e-01
GO:0010824 regulation of centrosome duplication	15	9.40e-01	-0.011200	9.96e-01
GO:0031593 polyubiquitin modification-dependent protein binding	19	9.33e-01	-0.011200	9.94e-01
GO:0004860 protein kinase inhibitor activity	18	9.35e-01	-0.011000	9.95e-01
GO:0005925 focal adhesion	114	8.39e-01	-0.011000	9.64e-01
GO:0031625 ubiquitin protein ligase binding	173	8.05e-01	-0.010900	9.51e-01
GO:0097191 extrinsic apoptotic signaling pathway	20	9.34e-01	-0.010800	9.94e-01
GO:0019900 kinase binding	49	8.98e-01	-0.010600	9.79e-01
GO:0030198 extracellular matrix organization	79	8.70e-01	0.010600	9.69e-01
GO:0001046 core promoter sequence-specific DNA binding	11	9.53e-01	0.010300	9.98e-01
GO:0050852 T cell receptor signaling pathway	49	9.03e-01	-0.010100	9.81e-01
GO:0010608 post-transcriptional regulation of gene expression	11	9.54e-01	-0.010100	9.98e-01
GO:0030036 actin cytoskeleton organization	106	8.58e-01	0.010100	9.64e-01
GO:0005525 GTP binding	213	8.02e-01	-0.009990	9.51e-01
GO:0005010 insulin-like growth factor receptor activity	13	9.50e-01	0.009950	9.98e-01
GO:0034244 negative regulation of transcription elongation by RNA polymerase II	13	9.51e-01	0.009940	9.98e-01
GO:0007219 Notch signaling pathway	42	9.11e-01	-0.009930	9.83e-01
GO:0036464 cytoplasmic ribonucleoprotein granule	36	9.18e-01	0.009910	9.86e-01
GO:1902894 negative regulation of miRNA transcription	12	9.54e-01	0.009700	9.98e-01
GO:0035994 response to muscle stretch	10	9.58e-01	-0.009630	9.98e-01
GO:0007283 spermatogenesis	101	8.67e-01	-0.009620	9.69e-01
GO:0033077 T cell differentiation in thymus	16	9.48e-01	-0.009370	9.98e-01
GO:0070063 RNA polymerase binding	12	9.56e-01	-0.009210	9.98e-01
GO:0006402 mRNA catabolic process	14	9.52e-01	0.009200	9.98e-01
GO:0045165 cell fate commitment	20	9.45e-01	0.008840	9.98e-01
GO:0043542 endothelial cell migration	14	9.55e-01	-0.008750	9.98e-01
GO:0034450 ubiquitin-ubiquitin ligase activity	12	9.58e-01	-0.008720	9.98e-01
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway	25	9.41e-01	0.008510	9.97e-01
GO:0031267 small GTPase binding	167	8.52e-01	0.008370	9.64e-01
GO:0071011 precatalytic spliceosome	12	9.60e-01	0.008300	9.98e-01
GO:0034237 protein kinase A regulatory subunit binding	15	9.56e-01	-0.008300	9.98e-01
GO:0015813 L-glutamate transmembrane transport	11	9.62e-01	0.008210	9.98e-01
GO:0007346 regulation of mitotic cell cycle	30	9.38e-01	0.008200	9.96e-01
GO:0000118 histone deacetylase complex	22	9.48e-01	-0.008060	9.98e-01
GO:0050853 B cell receptor signaling pathway	19	9.52e-01	-0.008030	9.98e-01
GO:0048488 synaptic vesicle endocytosis	21	9.50e-01	-0.007930	9.98e-01
GO:1905168 positive regulation of double-strand break repair via homologous recombination	25	9.46e-01	0.007880	9.98e-01
GO:0090734 site of DNA damage	22	9.50e-01	0.007780	9.98e-01
GO:0030054 cell junction	52	9.25e-01	0.007570	9.89e-01
GO:0019903 protein phosphatase binding	49	9.27e-01	0.007540	9.90e-01
GO:0051233 spindle midzone	17	9.58e-01	-0.007290	9.98e-01
GO:0007018 microtubule-based movement	41	9.36e-01	0.007280	9.95e-01
GO:0061630 ubiquitin protein ligase activity	178	8.70e-01	-0.007150	9.69e-01
GO:0032729 positive regulation of type II interferon production	21	9.55e-01	0.007120	9.98e-01
GO:0044295 axonal growth cone	10	9.69e-01	0.007080	9.98e-01
GO:0044344 cellular response to fibroblast growth factor stimulus	10	9.70e-01	0.006940	9.98e-01
GO:0032420 stereocilium	14	9.65e-01	0.006870	9.98e-01
GO:0019005 SCF ubiquitin ligase complex	43	9.40e-01	0.006660	9.96e-01
GO:0006099 tricarboxylic acid cycle	19	9.62e-01	0.006290	9.98e-01
GO:0012507 ER to Golgi transport vesicle membrane	11	9.72e-01	0.006130	9.98e-01
GO:0072518 Rho-dependent protein serine/threonine kinase activity	32	9.52e-01	0.006110	9.98e-01
GO:0036064 ciliary basal body	103	9.15e-01	0.006090	9.85e-01
GO:0034504 protein localization to nucleus	19	9.63e-01	0.006070	9.98e-01
GO:0043014 alpha-tubulin binding	23	9.60e-01	-0.005980	9.98e-01
GO:0019901 protein kinase binding	235	8.75e-01	0.005970	9.70e-01
GO:0032991 protein-containing complex	206	8.85e-01	-0.005860	9.74e-01
GO:0042802 identical protein binding	664	8.05e-01	0.005650	9.51e-01
GO:0016239 positive regulation of macroautophagy	17	9.69e-01	0.005370	9.98e-01
GO:0042127 regulation of cell population proliferation	45	9.51e-01	-0.005300	9.98e-01
GO:0045453 bone resorption	12	9.75e-01	0.005290	9.98e-01
GO:0008306 associative learning	11	9.76e-01	-0.005200	9.98e-01
GO:0032259 methylation	76	9.38e-01	-0.005200	9.96e-01
GO:0035403 histone H3T6 kinase activity	32	9.61e-01	-0.005040	9.98e-01
GO:0032481 positive regulation of type I interferon production	18	9.71e-01	0.004870	9.98e-01
GO:0003151 outflow tract morphogenesis	19	9.71e-01	0.004790	9.98e-01
GO:0005847 mRNA cleavage and polyadenylation specificity factor complex	11	9.79e-01	0.004590	9.98e-01
GO:0035024 negative regulation of Rho protein signal transduction	14	9.77e-01	-0.004360	9.98e-01
GO:0000922 spindle pole	69	9.54e-01	-0.003980	9.98e-01
GO:1990244 histone H2AT120 kinase activity	31	9.70e-01	-0.003940	9.98e-01
GO:0150052 regulation of postsynapse assembly	12	9.82e-01	-0.003860	9.98e-01
GO:0005737 cytoplasm	2182	7.77e-01	0.003790	9.44e-01
GO:0046718 symbiont entry into host cell	22	9.76e-01	-0.003650	9.98e-01
GO:0010008 endosome membrane	86	9.56e-01	-0.003450	9.98e-01
GO:0030522 intracellular receptor signaling pathway	18	9.80e-01	-0.003440	9.98e-01
GO:0001654 eye development	17	9.80e-01	-0.003430	9.98e-01
GO:0030217 T cell differentiation	18	9.80e-01	0.003410	9.98e-01
GO:0017018 myosin phosphatase activity	13	9.84e-01	-0.003240	9.98e-01
GO:0140791 histone H2AXS140 phosphatase activity	13	9.84e-01	-0.003240	9.98e-01
GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	13	9.84e-01	-0.003240	9.98e-01
GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	13	9.84e-01	-0.003240	9.98e-01
GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	13	9.84e-01	-0.003240	9.98e-01
GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	13	9.84e-01	-0.003240	9.98e-01
GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	13	9.84e-01	-0.003240	9.98e-01
GO:1990439 MAP kinase serine/threonine phosphatase activity	13	9.84e-01	-0.003240	9.98e-01
GO:0034067 protein localization to Golgi apparatus	13	9.84e-01	0.003160	9.98e-01
GO:0002224 toll-like receptor signaling pathway	15	9.83e-01	-0.003100	9.98e-01
GO:0030027 lamellipodium	91	9.60e-01	0.003030	9.98e-01
GO:0003756 protein disulfide isomerase activity	10	9.87e-01	0.002990	9.98e-01
GO:0006622 protein targeting to lysosome	15	9.84e-01	-0.002930	9.98e-01
GO:0070534 protein K63-linked ubiquitination	31	9.78e-01	0.002840	9.98e-01
GO:0007267 cell-cell signaling	13	9.86e-01	0.002780	9.98e-01
GO:0071480 cellular response to gamma radiation	14	9.86e-01	0.002780	9.98e-01
GO:0030863 cortical cytoskeleton	10	9.88e-01	-0.002770	9.98e-01
GO:0040018 positive regulation of multicellular organism growth	16	9.86e-01	-0.002510	9.98e-01
GO:0035402 histone H3T11 kinase activity	30	9.81e-01	-0.002460	9.98e-01
GO:0044022 histone H3S28 kinase activity	30	9.81e-01	-0.002460	9.98e-01
GO:0044023 histone H4S1 kinase activity	30	9.81e-01	-0.002460	9.98e-01
GO:0044024 histone H2AS1 kinase activity	30	9.81e-01	-0.002460	9.98e-01
GO:0044025 histone H2BS14 kinase activity	30	9.81e-01	-0.002460	9.98e-01
GO:0072371 histone H2AS121 kinase activity	30	9.81e-01	-0.002460	9.98e-01
GO:0140855 histone H3S57 kinase activity	30	9.81e-01	-0.002460	9.98e-01
GO:0140857 histone H3T45 kinase activity	30	9.81e-01	-0.002460	9.98e-01
GO:0004435 phosphatidylinositol phospholipase C activity	12	9.89e-01	0.002270	9.98e-01
GO:0032720 negative regulation of tumor necrosis factor production	18	9.87e-01	-0.002180	9.98e-01
GO:0030216 keratinocyte differentiation	27	9.86e-01	-0.001970	9.98e-01
GO:0006879 intracellular iron ion homeostasis	31	9.86e-01	-0.001870	9.98e-01
GO:0043113 receptor clustering	12	9.92e-01	-0.001660	9.98e-01
GO:0048147 negative regulation of fibroblast proliferation	15	9.92e-01	-0.001570	9.98e-01
GO:0035401 histone H3Y41 kinase activity	22	9.91e-01	0.001330	9.98e-01
GO:0001947 heart looping	22	9.92e-01	-0.001290	9.98e-01
GO:0005770 late endosome	75	9.87e-01	0.001110	9.98e-01
GO:1904047 S-adenosyl-L-methionine binding	13	9.95e-01	0.001050	9.98e-01
GO:0008053 mitochondrial fusion	17	9.94e-01	0.001040	9.98e-01
GO:0004676 3-phosphoinositide-dependent protein kinase activity	31	9.93e-01	-0.000923	9.98e-01
GO:0030154 cell differentiation	139	9.85e-01	0.000918	9.98e-01
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity	16	9.95e-01	0.000827	9.98e-01
GO:0048666 neuron development	26	9.95e-01	-0.000764	9.98e-01
GO:0001568 blood vessel development	20	9.95e-01	0.000737	9.98e-01
GO:0000287 magnesium ion binding	152	9.88e-01	-0.000680	9.98e-01
GO:0031290 retinal ganglion cell axon guidance	11	9.97e-01	-0.000670	9.98e-01
GO:0042169 SH2 domain binding	20	9.96e-01	0.000606	9.98e-01
GO:0043197 dendritic spine	46	9.96e-01	0.000450	9.98e-01
GO:0060041 retina development in camera-type eye	21	9.97e-01	0.000423	9.98e-01
GO:0070062 extracellular exosome	40	9.97e-01	0.000393	9.98e-01
GO:0140801 histone H2AXY142 kinase activity	23	9.98e-01	0.000303	9.98e-01
GO:0060271 cilium assembly	125	9.96e-01	0.000257	9.98e-01

---

Detailed Gene set reports

GO:0022625 cytosolic large ribosomal subunit

set	GO:0022625 cytosolic large ribosomal subunit
setSize	40
pANOVA	2.69e-12
s.dist	-0.639
p.adjustANOVA	2.39e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL32	-6882
RPL7L1	-6794
RPL14	-6704
RPL35	-6616
RPL7A	-6567
RPL11	-6558
RPL21	-6433
RPL34	-6266
RPL30	-6180
RPL23	-6176
RPL13	-6161
RPL10A	-6123
RPL24	-6095
RPL36	-6088
RPLP1	-6081
RPL35A	-6055
RPL31	-6047
RPL26L1	-6013
RPL27A	-5884
RPLP2	-5867

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL32	-6882
RPL7L1	-6794
RPL14	-6704
RPL35	-6616
RPL7A	-6567
RPL11	-6558
RPL21	-6433
RPL34	-6266
RPL30	-6180
RPL23	-6176
RPL13	-6161
RPL10A	-6123
RPL24	-6095
RPL36	-6088
RPLP1	-6081
RPL35A	-6055
RPL31	-6047
RPL26L1	-6013
RPL27A	-5884
RPLP2	-5867
RPL7	-5830
RPL9	-5786
RPL15	-5587
RPL5	-5233
RPL8	-5052
RPL27	-4997
RPLP0	-4558
RPL37	-4157
RPL29	-4057
RPL3	-3550
RPL12	-3427
RPL38	-3369
RPL19	-2956
RPL23A	-2828
RPL4	-1964
RPL18A	-1563
RPL6	-1490
RPL37A	-1155
ZCCHC17	49
RPL3L	247

---

GO:0031663 lipopolysaccharide-mediated signaling pathway

set	GO:0031663 lipopolysaccharide-mediated signaling pathway
setSize	10
pANOVA	0.00131
s.dist	-0.587
p.adjustANOVA	0.0604

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RIPK2	-6421
SCARB1	-6042
MTDH	-5085
PRKCE	-5031
MAPK3	-4378
MAPK14	-4237
PTAFR	-4121
LYN	-3419
IRAK2	-2933
TRAF6	-2866

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RIPK2	-6421
SCARB1	-6042
MTDH	-5085
PRKCE	-5031
MAPK3	-4378
MAPK14	-4237
PTAFR	-4121
LYN	-3419
IRAK2	-2933
TRAF6	-2866

---

GO:0009378 four-way junction helicase activity

set	GO:0009378 four-way junction helicase activity
setSize	13
pANOVA	0.000271
s.dist	0.583
p.adjustANOVA	0.0267

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	7025
MCM8	6289
BLM	5536
FANCM	5248
MCM3	4717
RECQL	4577
RECQL5	4549
WRN	4303
MCM5	3875
ERCC3	2133
CHD7	1892
CHD1	1709
MCM9	676

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	7025
MCM8	6289
BLM	5536
FANCM	5248
MCM3	4717
RECQL	4577
RECQL5	4549
WRN	4303
MCM5	3875
ERCC3	2133
CHD7	1892
CHD1	1709
MCM9	676

---

GO:0006695 cholesterol biosynthetic process

set	GO:0006695 cholesterol biosynthetic process
setSize	16
pANOVA	5.86e-05
s.dist	0.58
p.adjustANOVA	0.00743

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LSS	6924
SREBF1	6740
FDPS	6648
HMGCS1	6497
FDFT1	6431
MVD	6344
HSD17B7	6141
DHCR7	5967
HMGCR	5720
MVK	5498
PMVK	5298
LBR	4441
INSIG2	1803
HMGCS2	910
INSIG1	-4628
LIPA	-6462

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LSS	6924
SREBF1	6740
FDPS	6648
HMGCS1	6497
FDFT1	6431
MVD	6344
HSD17B7	6141
DHCR7	5967
HMGCR	5720
MVK	5498
PMVK	5298
LBR	4441
INSIG2	1803
HMGCS2	910
INSIG1	-4628
LIPA	-6462

---

GO:0035145 exon-exon junction complex

set	GO:0035145 exon-exon junction complex
setSize	10
pANOVA	0.00195
s.dist	0.566
p.adjustANOVA	0.0707

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SMG6	7003
CASC3	6913
SRSF1	5832
PNN	5667
THRAP3	5480
UPF2	4784
UPF3B	4739
TDRD3	1774
UPF1	-1076
UPF3A	-1982

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SMG6	7003
CASC3	6913
SRSF1	5832
PNN	5667
THRAP3	5480
UPF2	4784
UPF3B	4739
TDRD3	1774
UPF1	-1076
UPF3A	-1982

---

GO:0070182 DNA polymerase binding

set	GO:0070182 DNA polymerase binding
setSize	13
pANOVA	0.000489
s.dist	0.558
p.adjustANOVA	0.032

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SMG6	7003
FANCI	6888
HSP90AA1	6872
SMARCA4	6705
NAT10	6588
RTEL1	6550
FANCD2	5558
POLG2	5300
LONP1	4259
PCNA	3105
NABP2	-870
PTGES3	-2363
NHEJ1	-5411

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SMG6	7003
FANCI	6888
HSP90AA1	6872
SMARCA4	6705
NAT10	6588
RTEL1	6550
FANCD2	5558
POLG2	5300
LONP1	4259
PCNA	3105
NABP2	-870
PTGES3	-2363
NHEJ1	-5411

---

GO:0061749 forked DNA-dependent helicase activity

set	GO:0061749 forked DNA-dependent helicase activity
setSize	10
pANOVA	0.0025
s.dist	0.552
p.adjustANOVA	0.0778

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	7025
MCM8	6289
BLM	5536
MCM3	4717
WRN	4303
MCM5	3875
ERCC3	2133
CHD7	1892
CHD1	1709
MCM9	676

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	7025
MCM8	6289
BLM	5536
MCM3	4717
WRN	4303
MCM5	3875
ERCC3	2133
CHD7	1892
CHD1	1709
MCM9	676

---

GO:0000793 condensed chromosome

set	GO:0000793 condensed chromosome
setSize	13
pANOVA	0.000954
s.dist	0.529
p.adjustANOVA	0.047

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LIG4	6765
TOP3B	6756
RIF1	6287
HMGB2	6052
FANCD2	5558
NCAPD2	4403
TOP2A	3054
SMARCA5	3037
CDK2	2754
BAZ1B	1726
SMC2	656
NCAPG	342
CTCF	32

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LIG4	6765
TOP3B	6756
RIF1	6287
HMGB2	6052
FANCD2	5558
NCAPD2	4403
TOP2A	3054
SMARCA5	3037
CDK2	2754
BAZ1B	1726
SMC2	656
NCAPG	342
CTCF	32

---

GO:0070034 telomerase RNA binding

set	GO:0070034 telomerase RNA binding
setSize	12
pANOVA	0.00189
s.dist	0.518
p.adjustANOVA	0.0698

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SMG6	7003
SMG5	6981
DKC1	6499
EXOSC10	6498
GAR1	5755
SMG7	5337
PINX1	4908
DHX36	4467
HNRNPU	2079
NAF1	301
PARN	-1399
XRN1	-5624

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SMG6	7003
SMG5	6981
DKC1	6499
EXOSC10	6498
GAR1	5755
SMG7	5337
PINX1	4908
DHX36	4467
HNRNPU	2079
NAF1	301
PARN	-1399
XRN1	-5624

---

GO:0001965 G-protein alpha-subunit binding

set	GO:0001965 G-protein alpha-subunit binding
setSize	10
pANOVA	0.0047
s.dist	-0.516
p.adjustANOVA	0.107

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SASH1	-7446
RGS10	-7186
F2RL1	-6969
CCDC88A	-6783
RIC8A	-4798
RGS22	-4511
RGS2	-3670
GPSM1	-2735
RIC8B	-656
RGS14	5334

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SASH1	-7446
RGS10	-7186
F2RL1	-6969
CCDC88A	-6783
RIC8A	-4798
RGS22	-4511
RGS2	-3670
GPSM1	-2735
RIC8B	-656
RGS14	5334

---

GO:0003688 DNA replication origin binding

set	GO:0003688 DNA replication origin binding
setSize	12
pANOVA	0.00203
s.dist	0.514
p.adjustANOVA	0.0721

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CDC6	6996
DDX11	6918
ORC2	6677
MCM10	6131
CDC45	5962
MCM2	4211
MCM5	3875
ORC5	2663
ORC3	1243
KAT7	1022
ORC4	-368
POLA1	-2837

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CDC6	6996
DDX11	6918
ORC2	6677
MCM10	6131
CDC45	5962
MCM2	4211
MCM5	3875
ORC5	2663
ORC3	1243
KAT7	1022
ORC4	-368
POLA1	-2837

---

GO:1902774 late endosome to lysosome transport

set	GO:1902774 late endosome to lysosome transport
setSize	10
pANOVA	0.00592
s.dist	-0.503
p.adjustANOVA	0.122

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CHMP1B	-6980
VPS41	-6658
CHMP2A	-6209
VPS39	-4318
CHMP2B	-4204
CHMP5	-3641
CHMP7	-3271
CHMP4C	-2046
C9orf72	-1259
CHMP3	157

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CHMP1B	-6980
VPS41	-6658
CHMP2A	-6209
VPS39	-4318
CHMP2B	-4204
CHMP5	-3641
CHMP7	-3271
CHMP4C	-2046
C9orf72	-1259
CHMP3	157

---

GO:0030140 trans-Golgi network transport vesicle

set	GO:0030140 trans-Golgi network transport vesicle
setSize	11
pANOVA	0.00402
s.dist	-0.501
p.adjustANOVA	0.0968

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RAB26	-7165
IGF2R	-6891
ATP7A	-6858
SPG21	-6675
GOPC	-6554
RAB8A	-5730
RAB8B	-5690
CLRN1	-5285
RAB12	-3266
SORT1	5011
FURIN	6974

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RAB26	-7165
IGF2R	-6891
ATP7A	-6858
SPG21	-6675
GOPC	-6554
RAB8A	-5730
RAB8B	-5690
CLRN1	-5285
RAB12	-3266
SORT1	5011
FURIN	6974

---

GO:0036121 double-stranded DNA helicase activity

set	GO:0036121 double-stranded DNA helicase activity
setSize	11
pANOVA	0.00403
s.dist	0.501
p.adjustANOVA	0.0968

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	7025
MCM8	6289
BLM	5536
IGHMBP2	5080
MCM3	4717
MCM5	3875
ERCC3	2133
CHD7	1892
CHD1	1709
MCM9	676
UPF1	-1076

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	7025
MCM8	6289
BLM	5536
IGHMBP2	5080
MCM3	4717
MCM5	3875
ERCC3	2133
CHD7	1892
CHD1	1709
MCM9	676
UPF1	-1076

---

GO:0031929 TOR signaling

set	GO:0031929 TOR signaling
setSize	13
pANOVA	0.00189
s.dist	-0.498
p.adjustANOVA	0.0698

Top enriched genes

Top 20 genes

GeneID	Gene Rank
EIF4EBP1	-7084
HIF1A	-7067
EIF4EBP2	-6888
LIPA	-6462
TLDC1	-6442
PIK3AP1	-6381
RPS6	-5241
FLCN	-4863
MTM1	-4646
TIPRL	-574
MLST8	1057
RPS6KB1	2139
RPS6KB2	2964

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
EIF4EBP1	-7084
HIF1A	-7067
EIF4EBP2	-6888
LIPA	-6462
TLDC1	-6442
PIK3AP1	-6381
RPS6	-5241
FLCN	-4863
MTM1	-4646
TIPRL	-574
MLST8	1057
RPS6KB1	2139
RPS6KB2	2964

---

GO:0022627 cytosolic small ribosomal subunit

set	GO:0022627 cytosolic small ribosomal subunit
setSize	25
pANOVA	1.72e-05
s.dist	-0.497
p.adjustANOVA	0.00389

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS20	-7028
RPS21	-7017
RPS15A	-6768
RPS24	-6552
RPS28	-6379
RPS8	-6355
RPS4Y1	-6320
RPS15	-6308
RPS10	-6193
RPS2	-6109
RPS27L	-5757
RPS7	-5425
RPS12	-5341
RPS16	-5280
RPS6	-5241
RPS3A	-3980
RPS3	-3952
RPS23	-2264
RPS14	-2088
RPS11	-1682

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS20	-7028
RPS21	-7017
RPS15A	-6768
RPS24	-6552
RPS28	-6379
RPS8	-6355
RPS4Y1	-6320
RPS15	-6308
RPS10	-6193
RPS2	-6109
RPS27L	-5757
RPS7	-5425
RPS12	-5341
RPS16	-5280
RPS6	-5241
RPS3A	-3980
RPS3	-3952
RPS23	-2264
RPS14	-2088
RPS11	-1682
RPS26	489
RPS29	869
RPS13	1134
EIF2A	3410
LARP4	5251

---

GO:0003899 DNA-directed 5’-3’ RNA polymerase activity

set	GO:0003899 DNA-directed 5’-3’ RNA polymerase activity
setSize	10
pANOVA	0.0072
s.dist	0.491
p.adjustANOVA	0.14

Top enriched genes

Top 20 genes

GeneID	Gene Rank
POLR3H	6836
POLRMT	6564
POLR1B	6447
POLR2B	4961
POLR3B	4110
POLR2H	3328
POLR3A	3090
POLR2F	-386
POLR2I	-410
POLR3K	-844

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
POLR3H	6836
POLRMT	6564
POLR1B	6447
POLR2B	4961
POLR3B	4110
POLR2H	3328
POLR3A	3090
POLR2F	-386
POLR2I	-410
POLR3K	-844

---

GO:0006120 mitochondrial electron transport, NADH to ubiquinone

set	GO:0006120 mitochondrial electron transport, NADH to ubiquinone
setSize	19
pANOVA	0.000328
s.dist	-0.476
p.adjustANOVA	0.0277

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NDUFB8	-7243
ND5	-7062
NDUFS3	-6614
NDUFC2	-6530
NDUFA8	-6242
NDUFV2	-5853
NDUFA10	-5801
NDUFB9	-5799
ND2	-5608
NDUFB6	-5378
NDUFS6	-4256
NDUFS8	-4074
NDUFAF1	-3880
DNAJC15	-2530
NDUFS2	-1015
NDUFS1	809
DLD	998
NDUFS7	2715
NDUFV1	4058

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NDUFB8	-7243
ND5	-7062
NDUFS3	-6614
NDUFC2	-6530
NDUFA8	-6242
NDUFV2	-5853
NDUFA10	-5801
NDUFB9	-5799
ND2	-5608
NDUFB6	-5378
NDUFS6	-4256
NDUFS8	-4074
NDUFAF1	-3880
DNAJC15	-2530
NDUFS2	-1015
NDUFS1	809
DLD	998
NDUFS7	2715
NDUFV1	4058

---

GO:0006268 DNA unwinding involved in DNA replication

set	GO:0006268 DNA unwinding involved in DNA replication
setSize	14
pANOVA	0.00215
s.dist	0.474
p.adjustANOVA	0.0732

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GINS1	6325
RPA1	6057
CDC45	5962
MCM4	5545
SSBP1	5121
MCM3	4717
RECQL	4577
RECQL5	4549
WRN	4303
MCM2	4211
MCM5	3875
MCM6	-2758
PURA	-2805
GINS3	-4245

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GINS1	6325
RPA1	6057
CDC45	5962
MCM4	5545
SSBP1	5121
MCM3	4717
RECQL	4577
RECQL5	4549
WRN	4303
MCM2	4211
MCM5	3875
MCM6	-2758
PURA	-2805
GINS3	-4245

---

GO:0071806 protein transmembrane transport

set	GO:0071806 protein transmembrane transport
setSize	12
pANOVA	0.00479
s.dist	-0.47
p.adjustANOVA	0.108

Top enriched genes

Top 20 genes

GeneID	Gene Rank
EXOC4	-6894
IFT20	-6655
TMED10	-6147
EDNRA	-6089
TRIP11	-5435
RAB11A	-3646
TIMM22	-3077
DTNBP1	-2432
SEC61G	-1701
HPSE	-887
BLOC1S6	-186
EXOC7	-141

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
EXOC4	-6894
IFT20	-6655
TMED10	-6147
EDNRA	-6089
TRIP11	-5435
RAB11A	-3646
TIMM22	-3077
DTNBP1	-2432
SEC61G	-1701
HPSE	-887
BLOC1S6	-186
EXOC7	-141

---

GO:0022626 cytosolic ribosome

set	GO:0022626 cytosolic ribosome
setSize	13
pANOVA	0.00338
s.dist	0.47
p.adjustANOVA	0.0909

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ASCC2	6020
NEMF	5865
METAP1	5622
RNF25	4705
HBS1L	4646
LTN1	4234
RNF10	3181
USP10	2810
GSPT2	2138
GCN1	1408
PELO	1325
RNF14	1136
ETF1	-1303

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ASCC2	6020
NEMF	5865
METAP1	5622
RNF25	4705
HBS1L	4646
LTN1	4234
RNF10	3181
USP10	2810
GSPT2	2138
GCN1	1408
PELO	1325
RNF14	1136
ETF1	-1303

---

GO:0006749 glutathione metabolic process

set	GO:0006749 glutathione metabolic process
setSize	15
pANOVA	0.00172
s.dist	-0.468
p.adjustANOVA	0.0663

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HAGH	-7283
GSTO2	-7101
SOD1	-6264
ARL6IP5	-5768
SLC7A11	-5700
GSR	-5469
GPX1	-5350
GSTT1	-5080
CTNS	-3831
GSTM2	-3308
HPGDS	-2629
MMACHC	-936
TXNRD3	212
GSTK1	751
GSTZ1	3957

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HAGH	-7283
GSTO2	-7101
SOD1	-6264
ARL6IP5	-5768
SLC7A11	-5700
GSR	-5469
GPX1	-5350
GSTT1	-5080
CTNS	-3831
GSTM2	-3308
HPGDS	-2629
MMACHC	-936
TXNRD3	212
GSTK1	751
GSTZ1	3957

---

GO:0034314 Arp2/3 complex-mediated actin nucleation

set	GO:0034314 Arp2/3 complex-mediated actin nucleation
setSize	11
pANOVA	0.00748
s.dist	-0.466
p.adjustANOVA	0.143

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ARPC4	-7076
ARPC3	-6848
ARPC1A	-6472
ARPC2	-5848
ARPC5	-5663
WASHC1	-5099
ACTR3	-3148
JMY	-1665
ARPC1B	-1328
WHAMM	-691
ARPC5L	4515

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ARPC4	-7076
ARPC3	-6848
ARPC1A	-6472
ARPC2	-5848
ARPC5	-5663
WASHC1	-5099
ACTR3	-3148
JMY	-1665
ARPC1B	-1328
WHAMM	-691
ARPC5L	4515

---

GO:0006337 nucleosome disassembly

set	GO:0006337 nucleosome disassembly
setSize	10
pANOVA	0.0108
s.dist	0.466
p.adjustANOVA	0.167

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SMARCA4	6705
SMARCD1	6161
SMARCC1	5913
SMARCB1	5310
SSRP1	4946
SMARCD2	3783
SMARCE1	2856
ATAD2	305
ATAD2B	-434
ARID2	-3680

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SMARCA4	6705
SMARCD1	6161
SMARCC1	5913
SMARCB1	5310
SSRP1	4946
SMARCD2	3783
SMARCE1	2856
ATAD2	305
ATAD2B	-434
ARID2	-3680

---

GO:0060047 heart contraction

set	GO:0060047 heart contraction
setSize	10
pANOVA	0.0115
s.dist	-0.461
p.adjustANOVA	0.171

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SGCD	-7351
ATG5	-7064
SOD1	-6264
CDC42	-6028
GPX1	-5350
EXT2	-3754
ATP1A1	-3430
EXT1	-2786
DNM1L	-79
GATA6	6676

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SGCD	-7351
ATG5	-7064
SOD1	-6264
CDC42	-6028
GPX1	-5350
EXT2	-3754
ATP1A1	-3430
EXT1	-2786
DNM1L	-79
GATA6	6676

---

GO:0072583 clathrin-dependent endocytosis

set	GO:0072583 clathrin-dependent endocytosis
setSize	19
pANOVA	0.000543
s.dist	-0.458
p.adjustANOVA	0.0321

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GAS7	-7282
GAK	-7169
PICALM	-6569
CLTC	-6467
STON2	-6439
CLTA	-6431
AP2M1	-6213
SCYL2	-5975
GPR107	-5524
FNBP1L	-5482
AP2A2	-5256
LMBRD1	-2734
INPP5F	-2364
CLTB	-2285
CANX	-2055
AP2S1	-719
SNAP91	1156
AP2B1	4823
FCHSD2	6125

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GAS7	-7282
GAK	-7169
PICALM	-6569
CLTC	-6467
STON2	-6439
CLTA	-6431
AP2M1	-6213
SCYL2	-5975
GPR107	-5524
FNBP1L	-5482
AP2A2	-5256
LMBRD1	-2734
INPP5F	-2364
CLTB	-2285
CANX	-2055
AP2S1	-719
SNAP91	1156
AP2B1	4823
FCHSD2	6125

---

GO:0030658 transport vesicle membrane

set	GO:0030658 transport vesicle membrane
setSize	13
pANOVA	0.00432
s.dist	-0.457
p.adjustANOVA	0.101

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TMEM30A	-6868
CPE	-6575
ITPR2	-6479
TMED10	-6147
VAMP7	-5319
KIF1B	-5182
PAM	-4304
SPRED2	-3765
ITPR3	-3556
ECE2	-3235
SORL1	453
PTPRN	2399
ITPR1	2925

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TMEM30A	-6868
CPE	-6575
ITPR2	-6479
TMED10	-6147
VAMP7	-5319
KIF1B	-5182
PAM	-4304
SPRED2	-3765
ITPR3	-3556
ECE2	-3235
SORL1	453
PTPRN	2399
ITPR1	2925

---

GO:1904646 cellular response to amyloid-beta

set	GO:1904646 cellular response to amyloid-beta
setSize	10
pANOVA	0.0134
s.dist	-0.452
p.adjustANOVA	0.182

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CACNA2D1	-7281
LGMN	-7037
IGF1R	-6103
PSEN1	-5593
ITGA4	-5510
APP	-3955
SNX32	-3692
FYN	-1754
ABCC1	-554
EPHA4	6743

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CACNA2D1	-7281
LGMN	-7037
IGF1R	-6103
PSEN1	-5593
ITGA4	-5510
APP	-3955
SNX32	-3692
FYN	-1754
ABCC1	-554
EPHA4	6743

---

GO:0046326 positive regulation of D-glucose import

set	GO:0046326 positive regulation of D-glucose import
setSize	14
pANOVA	0.00421
s.dist	-0.442
p.adjustANOVA	0.0995

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NFE2L2	-7237
OSBPL8	-6873
APPL1	-6728
KLF15	-5983
INSR	-4977
AKT1	-4637
MAPK14	-4237
CLTCL1	-4138
MEF2A	-3328
CAPN10	-1771
SLC1A2	-1078
RHOQ	68
PRKCI	338
RNASEL	2975

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NFE2L2	-7237
OSBPL8	-6873
APPL1	-6728
KLF15	-5983
INSR	-4977
AKT1	-4637
MAPK14	-4237
CLTCL1	-4138
MEF2A	-3328
CAPN10	-1771
SLC1A2	-1078
RHOQ	68
PRKCI	338
RNASEL	2975

---

GO:0007129 homologous chromosome pairing at meiosis

set	GO:0007129 homologous chromosome pairing at meiosis
setSize	13
pANOVA	0.00637
s.dist	0.437
p.adjustANOVA	0.128

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PSMC3IP	6599
SGF29	6509
CCNE1	6126
MLH1	6068
FANCD2	5558
CCNE2	3595
SUN1	3331
MRE11	3185
NDC1	3074
SPATA22	1282
NAIF1	46
MAJIN	-2023
DMC1	-4627

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PSMC3IP	6599
SGF29	6509
CCNE1	6126
MLH1	6068
FANCD2	5558
CCNE2	3595
SUN1	3331
MRE11	3185
NDC1	3074
SPATA22	1282
NAIF1	46
MAJIN	-2023
DMC1	-4627

---

GO:0045271 respiratory chain complex I

set	GO:0045271 respiratory chain complex I
setSize	31
pANOVA	2.58e-05
s.dist	-0.437
p.adjustANOVA	0.00509

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NDUFB8	-7243
NDUFB5	-7226
ND5	-7062
NDUFS3	-6614
NDUFC2	-6530
NDUFA8	-6242
NDUFAB1	-6151
NDUFV2	-5853
NDUFA10	-5801
NDUFB9	-5799
ND2	-5608
NDUFB6	-5378
NDUFA12	-5225
NDUFB2	-5164
NDUFB4	-5005
NDUFB3	-4364
NDUFS6	-4256
NDUFS8	-4074
NDUFA6	-3914
NDUFS4	-3676

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NDUFB8	-7243
NDUFB5	-7226
ND5	-7062
NDUFS3	-6614
NDUFC2	-6530
NDUFA8	-6242
NDUFAB1	-6151
NDUFV2	-5853
NDUFA10	-5801
NDUFB9	-5799
ND2	-5608
NDUFB6	-5378
NDUFA12	-5225
NDUFB2	-5164
NDUFB4	-5005
NDUFB3	-4364
NDUFS6	-4256
NDUFS8	-4074
NDUFA6	-3914
NDUFS4	-3676
NDUFA5	-2271
NDUFA9	-1348
NDUFS2	-1015
NDUFA2	-874
NDUFB10	-92
NDUFS1	809
NDUFV3	1222
NDUFS5	1718
NDUFA13	2127
NDUFS7	2715
NDUFV1	4058

---

GO:0016581 NuRD complex

set	GO:0016581 NuRD complex
setSize	10
pANOVA	0.0171
s.dist	0.436
p.adjustANOVA	0.209

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MTA2	6571
GATAD2B	6433
MTA1	5950
RBBP4	5713
CHD5	4923
CHD4	4401
HDAC2	2834
RBBP7	-973
GATAD2A	-1368
HDAC1	-4796

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MTA2	6571
GATAD2B	6433
MTA1	5950
RBBP4	5713
CHD5	4923
CHD4	4401
HDAC2	2834
RBBP7	-973
GATAD2A	-1368
HDAC1	-4796

---

GO:0033344 cholesterol efflux

set	GO:0033344 cholesterol efflux
setSize	12
pANOVA	0.0091
s.dist	-0.435
p.adjustANOVA	0.152

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LIPA	-6462
ABCA5	-6316
STX12	-6240
SCARB1	-6042
APOB	-4213
APOA5	-4054
NPC2	-3924
SPG11	-3264
TSKU	-2449
SOAT1	-1417
COMT	-537
NPC1	4715

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LIPA	-6462
ABCA5	-6316
STX12	-6240
SCARB1	-6042
APOB	-4213
APOA5	-4054
NPC2	-3924
SPG11	-3264
TSKU	-2449
SOAT1	-1417
COMT	-537
NPC1	4715

---

GO:1990391 DNA repair complex

set	GO:1990391 DNA repair complex
setSize	10
pANOVA	0.0176
s.dist	0.434
p.adjustANOVA	0.212

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FANCI	6888
ASCC2	6020
FANCD2	5558
BRCA1	5528
ATM	4732
TP53BP1	2490
PALB2	2072
PHF21A	34
BRCA2	-1664
KDM1A	-2107

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FANCI	6888
ASCC2	6020
FANCD2	5558
BRCA1	5528
ATM	4732
TP53BP1	2490
PALB2	2072
PHF21A	34
BRCA2	-1664
KDM1A	-2107

---

GO:0030904 retromer complex

set	GO:0030904 retromer complex
setSize	15
pANOVA	0.00373
s.dist	-0.433
p.adjustANOVA	0.0959

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SNX3	-6975
DENND4C	-6576
VPS29L	-6238
RAB7A	-6117
VPS26A	-6025
SNX8	-5973
SNX27	-5328
SNX5	-4894
VPS35	-4639
SNX32	-3692
SNX12	-3004
TBC1D5	-2040
VPS29	1519
DENND5A	3216
VPS26B	6774

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SNX3	-6975
DENND4C	-6576
VPS29L	-6238
RAB7A	-6117
VPS26A	-6025
SNX8	-5973
SNX27	-5328
SNX5	-4894
VPS35	-4639
SNX32	-3692
SNX12	-3004
TBC1D5	-2040
VPS29	1519
DENND5A	3216
VPS26B	6774

---

GO:0050829 defense response to Gram-negative bacterium

set	GO:0050829 defense response to Gram-negative bacterium
setSize	11
pANOVA	0.013
s.dist	0.433
p.adjustANOVA	0.182

Top enriched genes

Top 20 genes

GeneID	Gene Rank
AQP1	6994
IL12B	6233
HMGB2	6052
OPTN	6045
DROSHA	5611
NFKBIZ	4966
MPEG1	3632
NOD1	2275
IL22RA1	-2724
AvBD14	-3196
PRKD1	-3475

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
AQP1	6994
IL12B	6233
HMGB2	6052
OPTN	6045
DROSHA	5611
NFKBIZ	4966
MPEG1	3632
NOD1	2275
IL22RA1	-2724
AvBD14	-3196
PRKD1	-3475

---

GO:0035371 microtubule plus-end

set	GO:0035371 microtubule plus-end
setSize	12
pANOVA	0.00988
s.dist	0.43
p.adjustANOVA	0.162

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KIF18B	6873
NUMA1	6587
MAPRE2	5861
NCKAP5	4854
MAPRE3	4780
KIF2C	4369
CLIP2	3799
SLAIN2	3229
CLIP1	2764
DCTN1	2567
KNSTRN	-3847
CKAP5	-6685

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KIF18B	6873
NUMA1	6587
MAPRE2	5861
NCKAP5	4854
MAPRE3	4780
KIF2C	4369
CLIP2	3799
SLAIN2	3229
CLIP1	2764
DCTN1	2567
KNSTRN	-3847
CKAP5	-6685

---

GO:0070530 K63-linked polyubiquitin modification-dependent protein binding

set	GO:0070530 K63-linked polyubiquitin modification-dependent protein binding
setSize	17
pANOVA	0.0022
s.dist	0.429
p.adjustANOVA	0.0737

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SQSTM1	7057
TNFAIP3	6384
WDR81	6099
OPTN	6045
TNIP2	5134
RNF169	5041
TAB2	4493
RNF168	4326
TAB3	4082
SPRTN	2654
OTUD7B	2406
UIMC1	1669
ATRIP	475
ZRANB1	-721
ZRANB3	-1512
PRPF8	-1783
OTUD7A	-2222

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SQSTM1	7057
TNFAIP3	6384
WDR81	6099
OPTN	6045
TNIP2	5134
RNF169	5041
TAB2	4493
RNF168	4326
TAB3	4082
SPRTN	2654
OTUD7B	2406
UIMC1	1669
ATRIP	475
ZRANB1	-721
ZRANB3	-1512
PRPF8	-1783
OTUD7A	-2222

---

GO:0030282 bone mineralization

set	GO:0030282 bone mineralization
setSize	23
pANOVA	0.000371
s.dist	-0.429
p.adjustANOVA	0.0297

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PRICKLE1	-7392
COL6A1	-7382
AXIN2	-7359
HIF1A	-7067
LGR4	-6849
ANKH	-6666
LOX	-6632
TMEM38B	-5255
ANXA2	-4975
SMPD3	-4178
IFITM5	-4132
RUNX2	-4110
SBDS	-3960
COL1A2	-2813
WNT11	-2691
PHOSPHO1	-1865
ALPL	-1000
SBNO2	-209
PTN	396
ATF4	855

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PRICKLE1	-7392
COL6A1	-7382
AXIN2	-7359
HIF1A	-7067
LGR4	-6849
ANKH	-6666
LOX	-6632
TMEM38B	-5255
ANXA2	-4975
SMPD3	-4178
IFITM5	-4132
RUNX2	-4110
SBDS	-3960
COL1A2	-2813
WNT11	-2691
PHOSPHO1	-1865
ALPL	-1000
SBNO2	-209
PTN	396
ATF4	855
KLF10	1533
FOSL2	2191
ENPP1	3567

---

GO:0035855 megakaryocyte development

set	GO:0035855 megakaryocyte development
setSize	10
pANOVA	0.019
s.dist	0.429
p.adjustANOVA	0.217

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SH2B3	6991
ZFPM1	6528
SRF	6491
WASF2	6236
VPS33B	3227
PIP4K2A	3164
MEIS1	881
MED1	-329
FLI1	-347
ZNF385A	-3666

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SH2B3	6991
ZFPM1	6528
SRF	6491
WASF2	6236
VPS33B	3227
PIP4K2A	3164
MEIS1	881
MED1	-329
FLI1	-347
ZNF385A	-3666

---

GO:0140662 ATP-dependent protein folding chaperone

set	GO:0140662 ATP-dependent protein folding chaperone
setSize	23
pANOVA	0.000385
s.dist	0.428
p.adjustANOVA	0.0297

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HSPA8	7011
HSP90AA1	6872
HYOU1	5997
HSPA4	5842
CCT3	5419
TRAP1	5250
HSPA9	4804
HSPD1	4749
CCT7	4660
HSPA5	4601
TCP1	4583
HSPA14	4396
HSPH1	3619
HSP90B1	3481
CCT2	2699
CCT8	2205
CCT5	1250
HSPA4L	438
HSPA13	-17
CCT4	-292

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HSPA8	7011
HSP90AA1	6872
HYOU1	5997
HSPA4	5842
CCT3	5419
TRAP1	5250
HSPA9	4804
HSPD1	4749
CCT7	4660
HSPA5	4601
TCP1	4583
HSPA14	4396
HSPH1	3619
HSP90B1	3481
CCT2	2699
CCT8	2205
CCT5	1250
HSPA4L	438
HSPA13	-17
CCT4	-292
TOR1A	-1840
CLPX	-2354
HSPA2	-6470

---

GO:0030501 positive regulation of bone mineralization

set	GO:0030501 positive regulation of bone mineralization
setSize	13
pANOVA	0.00776
s.dist	-0.427
p.adjustANOVA	0.143

Top enriched genes

Top 20 genes

GeneID	Gene Rank
OSR1	-7434
GPM6B	-7400
TMEM119	-7192
CD276	-6863
FBN2	-6385
BMPR1A	-6155
BMPR2	-5413
ATVR1	-3795
OSR2	-1720
ATP2B1	-31
FZD9	1589
FAM46A	3636
FAM20C	4402

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
OSR1	-7434
GPM6B	-7400
TMEM119	-7192
CD276	-6863
FBN2	-6385
BMPR1A	-6155
BMPR2	-5413
ATVR1	-3795
OSR2	-1720
ATP2B1	-31
FZD9	1589
FAM46A	3636
FAM20C	4402

---

GO:0001968 fibronectin binding

set	GO:0001968 fibronectin binding
setSize	10
pANOVA	0.0197
s.dist	0.426
p.adjustANOVA	0.22

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGFBP5	7062
THBS1	6623
ITGB3	5698
TNFAIP6	5186
ITGB1	4335
ITGAV	3642
LRRC15	2716
MYOC	2502
HSD17B12	-1633
CTSK	-7157

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGFBP5	7062
THBS1	6623
ITGB3	5698
TNFAIP6	5186
ITGB1	4335
ITGAV	3642
LRRC15	2716
MYOC	2502
HSD17B12	-1633
CTSK	-7157

---

GO:0006352 DNA-templated transcription initiation

set	GO:0006352 DNA-templated transcription initiation
setSize	11
pANOVA	0.0149
s.dist	0.424
p.adjustANOVA	0.195

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TAF4B	6859
NCOA6	6299
TBPL1	4875
TWISTNB	4564
TAF12	4047
TAF1	3869
SMARCA5	3037
TBP	2870
POLR2D	2289
RSF1	-648
GTF2B	-6343

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TAF4B	6859
NCOA6	6299
TBPL1	4875
TWISTNB	4564
TAF12	4047
TAF1	3869
SMARCA5	3037
TBP	2870
POLR2D	2289
RSF1	-648
GTF2B	-6343

---

GO:1990498 mitotic spindle microtubule

set	GO:1990498 mitotic spindle microtubule
setSize	10
pANOVA	0.0205
s.dist	0.423
p.adjustANOVA	0.223

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MAP1S	6801
HAUS3	6265
EML3	5895
HAUS1	5885
MAPRE1	4062
HNRNPU	2079
TUBG1	710
HAUS6	-413
HAUS8	-1083
HAUS2	-1405

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MAP1S	6801
HAUS3	6265
EML3	5895
HAUS1	5885
MAPRE1	4062
HNRNPU	2079
TUBG1	710
HAUS6	-413
HAUS8	-1083
HAUS2	-1405

---

GO:0005158 insulin receptor binding

set	GO:0005158 insulin receptor binding
setSize	13
pANOVA	0.00863
s.dist	-0.421
p.adjustANOVA	0.151

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SORBS1	-7127
IGF2	-7048
SNX4	-6796
CCDC88A	-6783
IGF1R	-6103
IRS4	-5250
PIK3R1	-5043
SNX2	-4200
LMBRD1	-2734
GRB10	-1545
SNX1	1191
ENPP1	3567
SHC1	5655

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SORBS1	-7127
IGF2	-7048
SNX4	-6796
CCDC88A	-6783
IGF1R	-6103
IRS4	-5250
PIK3R1	-5043
SNX2	-4200
LMBRD1	-2734
GRB10	-1545
SNX1	1191
ENPP1	3567
SHC1	5655

---

GO:0010811 positive regulation of cell-substrate adhesion

set	GO:0010811 positive regulation of cell-substrate adhesion
setSize	13
pANOVA	0.00877
s.dist	-0.42
p.adjustANOVA	0.151

Top enriched genes

Top 20 genes

GeneID	Gene Rank
JAK2	-6537
CCDC80	-5644
RSU1	-5512
PRKCE	-5031
COL26A1	-4680
NID1	-4480
NPNT	-3581
NDNF	-2643
ABI3BP	-1778
HSD17B12	-1633
EGFLAM	-1425
FBLN2	-1152
SPOCK2	1963

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
JAK2	-6537
CCDC80	-5644
RSU1	-5512
PRKCE	-5031
COL26A1	-4680
NID1	-4480
NPNT	-3581
NDNF	-2643
ABI3BP	-1778
HSD17B12	-1633
EGFLAM	-1425
FBLN2	-1152
SPOCK2	1963

---

GO:0003735 structural constituent of ribosome

set	GO:0003735 structural constituent of ribosome
setSize	118
pANOVA	4.37e-15
s.dist	-0.418
p.adjustANOVA	7.75e-12

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS20	-7028
RPS21	-7017
RPL32	-6882
RPS27A	-6836
RPL7L1	-6794
RPS15A	-6768
RPL14	-6704
MRPL36	-6641
MRPL24	-6629
RPL35	-6616
RPL11	-6558
RPS24	-6552
MRPL51	-6441
RPL21	-6433
RPS28	-6379
RPS8	-6355
RPS4Y1	-6320
MRPS11	-6310
RPS15	-6308
RPL34	-6266

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS20	-7028
RPS21	-7017
RPL32	-6882
RPS27A	-6836
RPL7L1	-6794
RPS15A	-6768
RPL14	-6704
MRPL36	-6641
MRPL24	-6629
RPL35	-6616
RPL11	-6558
RPS24	-6552
MRPL51	-6441
RPL21	-6433
RPS28	-6379
RPS8	-6355
RPS4Y1	-6320
MRPS11	-6310
RPS15	-6308
RPL34	-6266
RPS10	-6193
MRPL49	-6190
MRPS31	-6183
RPL30	-6180
RPL23	-6176
RPL13	-6161
RPL10A	-6123
RPS2	-6109
RPL24	-6095
RPL36	-6088
RPLP1	-6081
RPL35A	-6055
RPL31	-6047
RPL26L1	-6013
MRPS18A	-5960
RPL27A	-5884
RPLP2	-5867
RPL7	-5830
RPL9	-5786
RPS27L	-5757
MRPL17	-5756
RPL15	-5587
MRPL37	-5532
RPS7	-5425
MRPL13	-5387
RPS12	-5341
RPS16	-5280
RPS6	-5241
RPL5	-5233
MRPL16	-5227
MRPS21	-5109
RPL8	-5052
RPL27	-4997
MRPS30	-4749
RPS17	-4732
RPLP0	-4558
MRPS34	-4507
MRPS23	-4441
MRPL14	-4438
MRPL35	-4261
MRPL28	-4249
RPL37	-4157
RPL29	-4057
RPS3A	-3980
MRPL22	-3965
RPS3	-3952
MRPL19	-3553
RPL3	-3550
MRPS22	-3446
RPL12	-3427
RPL38	-3369
UBA52	-3239
RPL19	-2956
MRPS12	-2923
MRPS10	-2851
RPL23A	-2828
MRPS16	-2604
MRPL3	-2442
RPS23	-2264
RPS14	-2088
RPL4	-1964
RPS11	-1682
MRPL46	-1584
MRPL23	-1564
RPL18A	-1563
RPL6	-1490
RPL37A	-1155
MRPS9	-1100
MRPS14	-1021
MRPS35	-787
MRPL18	-570
MRPL12	-338
MRPS15	-260
MRPS2	-155
RPL3L	247
RPL22	280
DAP3	317
RPS26	489
RPS29	869
MRPS17	915
MRPL15	958
MRPL2	987
RPS13	1134
RPL22L1	1160
MRPL32	1263
MRPS6	1424
SRBD1	1898
MRPL21	2184
DDA1	2384
MRPS18C	2668
MRPS5	2903
MRPL20	3554
MRPL47	3960
MRPL27	4611
MRPS25	4877
MRPL10	4941
MRPL41	5730
MRPS7	6419

---

GO:0005049 nuclear export signal receptor activity

set	GO:0005049 nuclear export signal receptor activity
setSize	10
pANOVA	0.0227
s.dist	0.416
p.adjustANOVA	0.237

Top enriched genes

Top 20 genes

GeneID	Gene Rank
XPO5	6948
XPO6	6923
XPO7	5529
XPO1	3373
EIF4ENIF1	2667
NUP42	2577
CSE1L	2017
XPO4	178
CALR	-622
NUP214	-1325

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
XPO5	6948
XPO6	6923
XPO7	5529
XPO1	3373
EIF4ENIF1	2667
NUP42	2577
CSE1L	2017
XPO4	178
CALR	-622
NUP214	-1325

---

GO:0007042 lysosomal lumen acidification

set	GO:0007042 lysosomal lumen acidification
setSize	10
pANOVA	0.0254
s.dist	-0.408
p.adjustANOVA	0.252

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CLN6	-6971
TMEM9	-6667
LAMP1	-6002
LAMP2	-5967
CREG1	-4491
ATP6AP2	-4145
TMEM106B	-3788
TMEM199	4
CLN5	2016
PPT1	4445

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CLN6	-6971
TMEM9	-6667
LAMP1	-6002
LAMP2	-5967
CREG1	-4491
ATP6AP2	-4145
TMEM106B	-3788
TMEM199	4
CLN5	2016
PPT1	4445

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.4.2 (2024-10-31)
## Platform: x86_64-pc-linux-gnu
## Running under: Ubuntu 24.04.1 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.12.0 
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.12.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Australia/Melbourne
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] stats4    stats     graphics  grDevices utils     datasets  methods  
## [8] base     
## 
## other attached packages:
##  [1] pkgload_1.4.0               GGally_2.2.1               
##  [3] ggplot2_3.5.1               gtools_3.9.5               
##  [5] tibble_3.2.1                echarts4r_0.4.5            
##  [7] UpSetR_1.4.0                beeswarm_0.4.0             
##  [9] kableExtra_1.4.0            eulerr_7.0.2               
## [11] mitch_1.19.2                MASS_7.3-61                
## [13] gplots_3.2.0                DESeq2_1.44.0              
## [15] SummarizedExperiment_1.34.0 Biobase_2.64.0             
## [17] MatrixGenerics_1.16.0       matrixStats_1.4.1          
## [19] GenomicRanges_1.56.1        GenomeInfoDb_1.40.1        
## [21] IRanges_2.38.1              S4Vectors_0.42.1           
## [23] BiocGenerics_0.50.0         reshape2_1.4.4             
## [25] dplyr_1.1.4                 zoo_1.8-12                 
## 
## loaded via a namespace (and not attached):
##  [1] tidyselect_1.2.1        viridisLite_0.4.2       farver_2.1.2           
##  [4] bitops_1.0-9            fastmap_1.2.0           promises_1.3.2         
##  [7] digest_0.6.37           mime_0.12               lifecycle_1.0.4        
## [10] polylabelr_0.3.0        magrittr_2.0.3          compiler_4.4.2         
## [13] rlang_1.1.4             sass_0.4.9              tools_4.4.2            
## [16] yaml_2.3.10             knitr_1.49              labeling_0.4.3         
## [19] S4Arrays_1.4.1          htmlwidgets_1.6.4       DelayedArray_0.30.1    
## [22] xml2_1.3.6              plyr_1.8.9              RColorBrewer_1.1-3     
## [25] abind_1.4-8             BiocParallel_1.38.0     KernSmooth_2.23-24     
## [28] withr_3.0.2             purrr_1.0.2             polyclip_1.10-7        
## [31] grid_4.4.2              caTools_1.18.3          xtable_1.8-4           
## [34] colorspace_2.1-1        scales_1.3.0            cli_3.6.3              
## [37] rmarkdown_2.29          crayon_1.5.3            generics_0.1.3         
## [40] rstudioapi_0.17.1       httr_1.4.7              cachem_1.1.0           
## [43] stringr_1.5.1           zlibbioc_1.50.0         parallel_4.4.2         
## [46] XVector_0.44.0          vctrs_0.6.5             Matrix_1.7-1           
## [49] jsonlite_1.8.9          systemfonts_1.1.0       locfit_1.5-9.10        
## [52] jquerylib_0.1.4         tidyr_1.3.1             glue_1.8.0             
## [55] ggstats_0.7.0           codetools_0.2-20        stringi_1.8.4          
## [58] gtable_0.3.6            later_1.4.1             UCSC.utils_1.0.0       
## [61] munsell_0.5.1           pillar_1.10.0           htmltools_0.5.8.1      
## [64] GenomeInfoDbData_1.2.12 R6_2.5.1                evaluate_1.0.1         
## [67] shiny_1.10.0            lattice_0.22-6          httpuv_1.6.15          
## [70] bslib_0.8.0             Rcpp_1.0.13-1           svglite_2.1.3          
## [73] gridExtra_2.3           SparseArray_1.4.8       xfun_0.49              
## [76] pkgconfig_2.0.3

END of report