Mitch Report

date generated: 2025-01-14

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch

	stat
5_8S_rRNA	-1.5628256
A4GALT	0.7853344
AAAS	-0.1268337
AACS	2.4540601
AADAC	0.7419318
AADAT	1.1206428

Here are some metrics about the input data profile:

Profiling data metrics

	Profile metrics
num_genesets	5133
num_genes_in_profile	14207
duplicated_genes_present	0
num_profile_genes_in_sets	9167
num_profile_genes_not_in_sets	5040

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets:

Gene set metrics

	Gene sets metrics
num_genesets	5133
num_genesets_excluded	3369
num_genesets_included	1764

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

set	setSize	pANOVA	s.dist	p.adjustANOVA
GO:0022625 cytosolic large ribosomal subunit	40	2.13e-21	0.867	1.88e-18
GO:0002181 cytoplasmic translation	27	1.25e-11	0.753	4.41e-09
GO:0045116 protein neddylation	10	5.60e-05	0.736	2.41e-03
GO:0022627 cytosolic small ribosomal subunit	25	2.70e-10	0.729	5.13e-08
GO:0035145 exon-exon junction complex	10	1.12e-04	-0.705	3.95e-03
GO:0051393 alpha-actinin binding	10	1.29e-04	-0.699	4.46e-03
GO:0048041 focal adhesion assembly	14	2.52e-05	-0.650	1.22e-03
GO:0036121 double-stranded DNA helicase activity	11	3.05e-04	-0.629	8.26e-03
GO:0003735 structural constituent of ribosome	118	6.41e-32	0.626	1.13e-28
GO:0032585 multivesicular body membrane	12	2.99e-04	0.603	8.24e-03
GO:0006337 nucleosome disassembly	10	9.72e-04	-0.602	2.01e-02
GO:0030992 intraciliary transport particle B	15	9.99e-05	0.580	3.67e-03
GO:0000380 alternative mRNA splicing, via spliceosome	16	8.90e-05	-0.566	3.41e-03
GO:0140658 ATP-dependent chromatin remodeler activity	11	1.49e-03	-0.553	2.57e-02
GO:0060395 SMAD protein signal transduction	14	3.81e-04	-0.548	9.74e-03
GO:0042073 intraciliary transport	16	1.65e-04	0.544	5.48e-03
GO:0003148 outflow tract septum morphogenesis	12	1.33e-03	-0.535	2.37e-02
GO:0006120 mitochondrial electron transport, NADH to ubiquinone	19	7.27e-05	0.526	2.98e-03
GO:0000793 condensed chromosome	13	1.03e-03	-0.526	2.03e-02
GO:0070411 I-SMAD binding	11	2.62e-03	-0.524	3.92e-02
GO:0006412 translation	96	1.18e-18	0.521	6.94e-16
GO:1902774 late endosome to lysosome transport	10	4.43e-03	0.520	5.69e-02
GO:0070182 DNA polymerase binding	13	1.19e-03	-0.519	2.21e-02
GO:0004602 glutathione peroxidase activity	12	2.59e-03	0.502	3.91e-02
GO:0008593 regulation of Notch signaling pathway	10	6.67e-03	0.495	7.36e-02
GO:0032968 positive regulation of transcription elongation by RNA polymerase II	15	1.03e-03	-0.489	2.03e-02
GO:0034727 piecemeal microautophagy of the nucleus	13	2.35e-03	0.487	3.67e-02
GO:0070577 lysine-acetylated histone binding	16	7.93e-04	-0.485	1.75e-02
GO:0061749 forked DNA-dependent helicase activity	10	8.00e-03	-0.484	8.02e-02
GO:0009653 anatomical structure morphogenesis	22	9.11e-05	-0.482	3.42e-03
GO:0046849 bone remodeling	10	8.60e-03	-0.480	8.43e-02
GO:0001725 stress fiber	42	8.09e-08	-0.478	7.51e-06
GO:0060045 positive regulation of cardiac muscle cell proliferation	13	3.03e-03	-0.475	4.27e-02
GO:0070034 telomerase RNA binding	12	4.52e-03	-0.473	5.70e-02
GO:0060379 cardiac muscle cell myoblast differentiation	10	1.00e-02	-0.470	9.00e-02
GO:0000245 spliceosomal complex assembly	10	1.01e-02	-0.470	9.00e-02
GO:1900181 negative regulation of protein localization to nucleus	11	7.14e-03	-0.468	7.64e-02
GO:0005840 ribosome	43	1.13e-07	0.468	9.98e-06
GO:0006641 triglyceride metabolic process	10	1.06e-02	0.467	9.30e-02
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway	11	7.51e-03	0.465	7.80e-02
GO:0016442 RISC complex	11	7.97e-03	-0.462	8.02e-02
GO:0045271 respiratory chain complex I	31	9.10e-06	0.461	5.35e-04
GO:0043296 apical junction complex	10	1.18e-02	-0.460	1.01e-01
GO:0030016 myofibril	14	2.93e-03	-0.459	4.20e-02
GO:0004364 glutathione transferase activity	10	1.21e-02	0.458	1.03e-01
GO:0030900 forebrain development	20	4.01e-04	-0.457	9.97e-03
GO:1990518 single-stranded 3’-5’ DNA helicase activity	11	8.82e-03	-0.456	8.55e-02
GO:0031466 Cul5-RING ubiquitin ligase complex	11	8.95e-03	0.455	8.58e-02
GO:0009888 tissue development	18	8.36e-04	-0.455	1.78e-02
GO:0017056 structural constituent of nuclear pore	19	6.52e-04	-0.452	1.52e-02

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
GO:0022625 cytosolic large ribosomal subunit	40	2.13e-21	8.67e-01	1.88e-18
GO:0002181 cytoplasmic translation	27	1.25e-11	7.53e-01	4.41e-09
GO:0045116 protein neddylation	10	5.60e-05	7.36e-01	2.41e-03
GO:0022627 cytosolic small ribosomal subunit	25	2.70e-10	7.29e-01	5.13e-08
GO:0035145 exon-exon junction complex	10	1.12e-04	-7.05e-01	3.95e-03
GO:0051393 alpha-actinin binding	10	1.29e-04	-6.99e-01	4.46e-03
GO:0048041 focal adhesion assembly	14	2.52e-05	-6.50e-01	1.22e-03
GO:0036121 double-stranded DNA helicase activity	11	3.05e-04	-6.29e-01	8.26e-03
GO:0003735 structural constituent of ribosome	118	6.41e-32	6.26e-01	1.13e-28
GO:0032585 multivesicular body membrane	12	2.99e-04	6.03e-01	8.24e-03
GO:0006337 nucleosome disassembly	10	9.72e-04	-6.02e-01	2.01e-02
GO:0030992 intraciliary transport particle B	15	9.99e-05	5.80e-01	3.67e-03
GO:0000380 alternative mRNA splicing, via spliceosome	16	8.90e-05	-5.66e-01	3.41e-03
GO:0140658 ATP-dependent chromatin remodeler activity	11	1.49e-03	-5.53e-01	2.57e-02
GO:0060395 SMAD protein signal transduction	14	3.81e-04	-5.48e-01	9.74e-03
GO:0042073 intraciliary transport	16	1.65e-04	5.44e-01	5.48e-03
GO:0003148 outflow tract septum morphogenesis	12	1.33e-03	-5.35e-01	2.37e-02
GO:0006120 mitochondrial electron transport, NADH to ubiquinone	19	7.27e-05	5.26e-01	2.98e-03
GO:0000793 condensed chromosome	13	1.03e-03	-5.26e-01	2.03e-02
GO:0070411 I-SMAD binding	11	2.62e-03	-5.24e-01	3.92e-02
GO:0006412 translation	96	1.18e-18	5.21e-01	6.94e-16
GO:1902774 late endosome to lysosome transport	10	4.43e-03	5.20e-01	5.69e-02
GO:0070182 DNA polymerase binding	13	1.19e-03	-5.19e-01	2.21e-02
GO:0004602 glutathione peroxidase activity	12	2.59e-03	5.02e-01	3.91e-02
GO:0008593 regulation of Notch signaling pathway	10	6.67e-03	4.95e-01	7.36e-02
GO:0032968 positive regulation of transcription elongation by RNA polymerase II	15	1.03e-03	-4.89e-01	2.03e-02
GO:0034727 piecemeal microautophagy of the nucleus	13	2.35e-03	4.87e-01	3.67e-02
GO:0070577 lysine-acetylated histone binding	16	7.93e-04	-4.85e-01	1.75e-02
GO:0061749 forked DNA-dependent helicase activity	10	8.00e-03	-4.84e-01	8.02e-02
GO:0009653 anatomical structure morphogenesis	22	9.11e-05	-4.82e-01	3.42e-03
GO:0046849 bone remodeling	10	8.60e-03	-4.80e-01	8.43e-02
GO:0001725 stress fiber	42	8.09e-08	-4.78e-01	7.51e-06
GO:0060045 positive regulation of cardiac muscle cell proliferation	13	3.03e-03	-4.75e-01	4.27e-02
GO:0070034 telomerase RNA binding	12	4.52e-03	-4.73e-01	5.70e-02
GO:0060379 cardiac muscle cell myoblast differentiation	10	1.00e-02	-4.70e-01	9.00e-02
GO:0000245 spliceosomal complex assembly	10	1.01e-02	-4.70e-01	9.00e-02
GO:1900181 negative regulation of protein localization to nucleus	11	7.14e-03	-4.68e-01	7.64e-02
GO:0005840 ribosome	43	1.13e-07	4.68e-01	9.98e-06
GO:0006641 triglyceride metabolic process	10	1.06e-02	4.67e-01	9.30e-02
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway	11	7.51e-03	4.65e-01	7.80e-02
GO:0016442 RISC complex	11	7.97e-03	-4.62e-01	8.02e-02
GO:0045271 respiratory chain complex I	31	9.10e-06	4.61e-01	5.35e-04
GO:0043296 apical junction complex	10	1.18e-02	-4.60e-01	1.01e-01
GO:0030016 myofibril	14	2.93e-03	-4.59e-01	4.20e-02
GO:0004364 glutathione transferase activity	10	1.21e-02	4.58e-01	1.03e-01
GO:0030900 forebrain development	20	4.01e-04	-4.57e-01	9.97e-03
GO:1990518 single-stranded 3’-5’ DNA helicase activity	11	8.82e-03	-4.56e-01	8.55e-02
GO:0031466 Cul5-RING ubiquitin ligase complex	11	8.95e-03	4.55e-01	8.58e-02
GO:0009888 tissue development	18	8.36e-04	-4.55e-01	1.78e-02
GO:0017056 structural constituent of nuclear pore	19	6.52e-04	-4.52e-01	1.52e-02
GO:0001894 tissue homeostasis	13	4.87e-03	-4.51e-01	6.09e-02
GO:0071816 tail-anchored membrane protein insertion into ER membrane	10	1.36e-02	4.50e-01	1.10e-01
GO:0044458 motile cilium assembly	12	6.98e-03	4.50e-01	7.50e-02
GO:1990391 DNA repair complex	10	1.46e-02	-4.46e-01	1.13e-01
GO:1990023 mitotic spindle midzone	10	1.48e-02	-4.45e-01	1.13e-01
GO:0006749 glutathione metabolic process	15	3.03e-03	4.42e-01	4.27e-02
GO:0051721 protein phosphatase 2A binding	14	4.18e-03	-4.42e-01	5.54e-02
GO:0050768 negative regulation of neurogenesis	10	1.58e-02	-4.41e-01	1.19e-01
GO:0034314 Arp2/3 complex-mediated actin nucleation	11	1.15e-02	4.40e-01	9.92e-02
GO:0005852 eukaryotic translation initiation factor 3 complex	10	1.61e-02	4.39e-01	1.21e-01
GO:0097038 perinuclear endoplasmic reticulum	10	1.67e-02	4.37e-01	1.24e-01
GO:0051603 proteolysis involved in protein catabolic process	23	2.90e-04	4.37e-01	8.24e-03
GO:0002053 positive regulation of mesenchymal cell proliferation	11	1.26e-02	-4.34e-01	1.05e-01
GO:0000228 nuclear chromosome	13	6.82e-03	-4.33e-01	7.38e-02
GO:0022604 regulation of cell morphogenesis	14	5.38e-03	-4.30e-01	6.50e-02
GO:0043240 Fanconi anaemia nuclear complex	11	1.47e-02	4.25e-01	1.13e-01
GO:0030331 nuclear estrogen receptor binding	19	1.36e-03	-4.24e-01	2.40e-02
GO:0008137 NADH dehydrogenase (ubiquinone) activity	10	2.15e-02	4.20e-01	1.44e-01
GO:0043995 histone H4K5 acetyltransferase activity	10	2.16e-02	-4.19e-01	1.44e-01
GO:0043996 histone H4K8 acetyltransferase activity	10	2.16e-02	-4.19e-01	1.44e-01
GO:0140416 transcription regulator inhibitor activity	12	1.20e-02	-4.19e-01	1.02e-01
GO:0031468 nuclear membrane reassembly	11	1.66e-02	4.17e-01	1.23e-01
GO:0030127 COPII vesicle coat	10	2.34e-02	4.14e-01	1.49e-01
GO:0045292 mRNA cis splicing, via spliceosome	13	1.01e-02	-4.12e-01	9.00e-02
GO:0000987 cis-regulatory region sequence-specific DNA binding	21	1.08e-03	-4.12e-01	2.08e-02
GO:0051642 centrosome localization	14	7.64e-03	4.12e-01	7.88e-02
GO:0048018 receptor ligand activity	18	2.55e-03	-4.11e-01	3.88e-02
GO:0032981 mitochondrial respiratory chain complex I assembly	38	1.39e-05	4.08e-01	7.41e-04
GO:0019003 GDP binding	44	3.11e-06	4.06e-01	2.20e-04
GO:0003724 RNA helicase activity	37	2.07e-05	-4.04e-01	1.05e-03
GO:0002040 sprouting angiogenesis	19	2.38e-03	-4.03e-01	3.68e-02
GO:0006488 dolichol-linked oligosaccharide biosynthetic process	14	9.72e-03	3.99e-01	8.99e-02
GO:0004181 metallocarboxypeptidase activity	11	2.28e-02	-3.97e-01	1.49e-01
GO:0003180 aortic valve morphogenesis	10	3.01e-02	-3.96e-01	1.76e-01
GO:1905564 positive regulation of vascular endothelial cell proliferation	10	3.07e-02	3.95e-01	1.76e-01
GO:1903076 regulation of protein localization to plasma membrane	18	3.83e-03	3.94e-01	5.12e-02
GO:0030100 regulation of endocytosis	12	1.86e-02	3.93e-01	1.31e-01
GO:0032924 activin receptor signaling pathway	12	1.88e-02	-3.92e-01	1.32e-01
GO:0033290 eukaryotic 48S preinitiation complex	13	1.45e-02	3.92e-01	1.13e-01
GO:0005665 RNA polymerase II, core complex	10	3.21e-02	3.92e-01	1.80e-01
GO:1902895 positive regulation of miRNA transcription	25	7.43e-04	-3.90e-01	1.68e-02
GO:0031623 receptor internalization	21	2.07e-03	3.88e-01	3.35e-02
GO:2000352 negative regulation of endothelial cell apoptotic process	14	1.28e-02	3.84e-01	1.06e-01
GO:0001732 formation of cytoplasmic translation initiation complex	12	2.14e-02	3.84e-01	1.44e-01
GO:0043425 bHLH transcription factor binding	10	3.59e-02	-3.83e-01	1.88e-01
GO:0009378 four-way junction helicase activity	13	1.71e-02	-3.82e-01	1.25e-01
GO:1902894 negative regulation of miRNA transcription	12	2.20e-02	-3.82e-01	1.46e-01
GO:0097225 sperm midpiece	14	1.38e-02	3.80e-01	1.10e-01
GO:0030030 cell projection organization	13	1.81e-02	3.79e-01	1.30e-01
GO:0015908 fatty acid transport	11	2.98e-02	3.78e-01	1.76e-01
GO:0060170 ciliary membrane	19	4.39e-03	3.78e-01	5.69e-02
GO:0000423 mitophagy	31	2.79e-04	3.77e-01	8.08e-03
GO:0035615 clathrin adaptor activity	10	3.93e-02	3.76e-01	1.99e-01
GO:0050885 neuromuscular process controlling balance	23	1.96e-03	-3.73e-01	3.26e-02
GO:0010718 positive regulation of epithelial to mesenchymal transition	26	1.00e-03	-3.73e-01	2.01e-02
GO:1990841 promoter-specific chromatin binding	34	1.70e-04	-3.73e-01	5.55e-03
GO:0007492 endoderm development	10	4.14e-02	-3.73e-01	2.05e-01
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane	18	6.46e-03	3.71e-01	7.31e-02
GO:0007162 negative regulation of cell adhesion	16	1.03e-02	-3.70e-01	9.14e-02
GO:0008089 anterograde axonal transport	10	4.38e-02	3.68e-01	2.14e-01
GO:0003678 DNA helicase activity	20	4.45e-03	-3.67e-01	5.69e-02
GO:0030513 positive regulation of BMP signaling pathway	19	5.75e-03	-3.66e-01	6.85e-02
GO:0061952 midbody abscission	14	1.82e-02	3.64e-01	1.30e-01
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage	24	2.02e-03	-3.64e-01	3.29e-02
GO:0006468 protein phosphorylation	12	2.99e-02	-3.62e-01	1.76e-01
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand	12	3.00e-02	-3.62e-01	1.76e-01
GO:0005201 extracellular matrix structural constituent	12	3.00e-02	-3.62e-01	1.76e-01
GO:0098869 cellular oxidant detoxification	28	9.37e-04	3.61e-01	1.97e-02
GO:0050905 neuromuscular process	10	4.79e-02	3.61e-01	2.25e-01
GO:0035278 miRNA-mediated gene silencing by inhibition of translation	12	3.03e-02	-3.61e-01	1.76e-01
GO:0007017 microtubule-based process	11	3.83e-02	3.61e-01	1.96e-01
GO:0005544 calcium-dependent phospholipid binding	21	4.30e-03	3.60e-01	5.62e-02
GO:0038061 non-canonical NF-kappaB signal transduction	11	4.03e-02	-3.57e-01	2.03e-01
GO:0043997 histone H4K12 acetyltransferase activity	10	5.06e-02	-3.57e-01	2.31e-01
GO:0070161 anchoring junction	18	8.93e-03	-3.56e-01	8.58e-02
GO:0016514 SWI/SNF complex	20	5.88e-03	-3.56e-01	6.96e-02
GO:0044322 endoplasmic reticulum quality control compartment	11	4.11e-02	3.56e-01	2.05e-01
GO:0000407 phagophore assembly site	20	5.96e-03	3.55e-01	6.96e-02
GO:2000737 negative regulation of stem cell differentiation	12	3.31e-02	-3.55e-01	1.83e-01
GO:0032391 photoreceptor connecting cilium	19	7.36e-03	3.55e-01	7.73e-02
GO:0055013 cardiac muscle cell development	11	4.15e-02	-3.55e-01	2.05e-01
GO:0055074 calcium ion homeostasis	18	9.12e-03	3.55e-01	8.64e-02
GO:0140374 antiviral innate immune response	19	7.51e-03	3.54e-01	7.80e-02
GO:0061484 hematopoietic stem cell homeostasis	12	3.43e-02	-3.53e-01	1.85e-01
GO:0042813 Wnt receptor activity	12	3.51e-02	-3.51e-01	1.87e-01
GO:0006913 nucleocytoplasmic transport	18	1.01e-02	-3.50e-01	9.00e-02
GO:0043409 negative regulation of MAPK cascade	20	6.77e-03	-3.50e-01	7.38e-02
GO:0045665 negative regulation of neuron differentiation	24	3.17e-03	-3.48e-01	4.36e-02
GO:0016226 iron-sulfur cluster assembly	17	1.30e-02	3.48e-01	1.06e-01
GO:0048278 vesicle docking	13	3.06e-02	3.46e-01	1.76e-01
GO:0008094 ATP-dependent activity, acting on DNA	11	4.69e-02	-3.46e-01	2.22e-01
GO:0034045 phagophore assembly site membrane	12	3.83e-02	3.45e-01	1.96e-01
GO:0043408 regulation of MAPK cascade	21	6.16e-03	-3.45e-01	7.12e-02
GO:0006744 ubiquinone biosynthetic process	11	4.77e-02	3.45e-01	2.24e-01
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	12	3.92e-02	3.44e-01	1.99e-01
GO:0006334 nucleosome assembly	27	2.00e-03	-3.44e-01	3.29e-02
GO:1904646 cellular response to amyloid-beta	10	6.13e-02	3.42e-01	2.57e-01
GO:0001675 acrosome assembly	11	5.05e-02	3.41e-01	2.31e-01
GO:0031490 chromatin DNA binding	40	1.97e-04	-3.40e-01	6.21e-03
GO:0061709 reticulophagy	15	2.28e-02	3.40e-01	1.49e-01
GO:0031929 TOR signaling	13	3.41e-02	3.40e-01	1.84e-01
GO:0010842 retina layer formation	11	5.17e-02	-3.39e-01	2.33e-01
GO:1903077 negative regulation of protein localization to plasma membrane	14	2.84e-02	3.38e-01	1.73e-01
GO:0080008 Cul4-RING E3 ubiquitin ligase complex	13	3.52e-02	-3.37e-01	1.87e-01
GO:0001046 core promoter sequence-specific DNA binding	11	5.27e-02	-3.37e-01	2.35e-01
GO:0005049 nuclear export signal receptor activity	10	6.66e-02	-3.35e-01	2.66e-01
GO:0001702 gastrulation with mouth forming second	10	6.68e-02	-3.35e-01	2.66e-01
GO:0009792 embryo development ending in birth or egg hatching	10	6.70e-02	-3.35e-01	2.66e-01
GO:0045216 cell-cell junction organization	13	3.68e-02	-3.35e-01	1.91e-01
GO:0031681 G-protein beta-subunit binding	10	6.93e-02	3.32e-01	2.69e-01
GO:0001618 virus receptor activity	10	7.03e-02	-3.31e-01	2.70e-01
GO:0005882 intermediate filament	20	1.06e-02	-3.30e-01	9.30e-02
GO:0030316 osteoclast differentiation	28	2.54e-03	-3.30e-01	3.88e-02
GO:0005828 kinetochore microtubule	10	7.14e-02	3.29e-01	2.74e-01
GO:0007042 lysosomal lumen acidification	10	7.21e-02	3.29e-01	2.75e-01
GO:0046961 proton-transporting ATPase activity, rotational mechanism	14	3.36e-02	3.28e-01	1.84e-01
GO:0048854 brain morphogenesis	14	3.52e-02	3.25e-01	1.87e-01
GO:0061351 neural precursor cell proliferation	15	2.94e-02	-3.25e-01	1.76e-01
GO:0045669 positive regulation of osteoblast differentiation	38	5.37e-04	-3.25e-01	1.31e-02
GO:0106222 lncRNA binding	17	2.07e-02	-3.24e-01	1.43e-01
GO:0030509 BMP signaling pathway	37	6.56e-04	-3.24e-01	1.52e-02
GO:0031663 lipopolysaccharide-mediated signaling pathway	11	6.33e-02	3.23e-01	2.62e-01
GO:0005763 mitochondrial small ribosomal subunit	21	1.04e-02	3.23e-01	9.14e-02
GO:0050767 regulation of neurogenesis	13	4.44e-02	-3.22e-01	2.14e-01
GO:0070412 R-SMAD binding	13	4.44e-02	-3.22e-01	2.14e-01
GO:0051536 iron-sulfur cluster binding	12	5.40e-02	3.21e-01	2.38e-01
GO:0030133 transport vesicle	23	7.74e-03	3.21e-01	7.91e-02
GO:0005777 peroxisome	49	1.05e-04	3.20e-01	3.77e-03
GO:0000460 maturation of 5.8S rRNA	11	6.62e-02	3.20e-01	2.66e-01
GO:0005158 insulin receptor binding	13	4.58e-02	-3.20e-01	2.19e-01
GO:0032720 negative regulation of tumor necrosis factor production	17	2.26e-02	-3.19e-01	1.49e-01
GO:0042474 middle ear morphogenesis	10	8.06e-02	3.19e-01	2.94e-01
GO:0001819 positive regulation of cytokine production	13	4.64e-02	3.19e-01	2.20e-01
GO:0010977 negative regulation of neuron projection development	17	2.32e-02	-3.18e-01	1.49e-01
GO:0002218 activation of innate immune response	17	2.36e-02	-3.17e-01	1.50e-01
GO:0090110 COPII-coated vesicle cargo loading	10	8.26e-02	3.17e-01	2.98e-01
GO:0120163 negative regulation of cold-induced thermogenesis	21	1.22e-02	-3.16e-01	1.03e-01
GO:0016581 NuRD complex	10	8.45e-02	-3.15e-01	3.01e-01
GO:0016236 macroautophagy	16	2.91e-02	3.15e-01	1.75e-01
GO:0048873 homeostasis of number of cells within a tissue	15	3.48e-02	-3.15e-01	1.87e-01
GO:0071889 14-3-3 protein binding	15	3.55e-02	-3.14e-01	1.88e-01
GO:1904294 positive regulation of ERAD pathway	10	8.63e-02	3.13e-01	3.04e-01
GO:0061631 ubiquitin conjugating enzyme activity	24	8.06e-03	3.12e-01	8.02e-02
GO:1990247 N6-methyladenosine-containing RNA reader activity	10	8.84e-02	-3.11e-01	3.08e-01
GO:0050808 synapse organization	17	2.66e-02	-3.11e-01	1.65e-01
GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site	16	3.21e-02	3.09e-01	1.80e-01
GO:0002088 lens development in camera-type eye	13	5.34e-02	-3.09e-01	2.36e-01
GO:0007249 canonical NF-kappaB signal transduction	18	2.32e-02	-3.09e-01	1.49e-01
GO:0005771 multivesicular body	21	1.42e-02	3.09e-01	1.13e-01
GO:0098609 cell-cell adhesion	83	1.21e-06	-3.08e-01	9.72e-05
GO:0035064 methylated histone binding	42	5.57e-04	-3.08e-01	1.34e-02
GO:0071806 protein transmembrane transport	12	6.55e-02	3.07e-01	2.66e-01
GO:0035914 skeletal muscle cell differentiation	24	9.24e-03	-3.07e-01	8.67e-02
GO:0030031 cell projection assembly	10	9.29e-02	3.07e-01	3.18e-01
GO:0048812 neuron projection morphogenesis	29	4.25e-03	-3.07e-01	5.59e-02
GO:0140693 molecular condensate scaffold activity	24	9.37e-03	-3.06e-01	8.75e-02
GO:0140861 DNA repair-dependent chromatin remodeling	14	4.72e-02	-3.06e-01	2.23e-01
GO:0035925 mRNA 3’-UTR AU-rich region binding	13	5.60e-02	3.06e-01	2.43e-01
GO:0004197 cysteine-type endopeptidase activity	37	1.27e-03	3.06e-01	2.32e-02
GO:0031669 cellular response to nutrient levels	12	6.65e-02	-3.06e-01	2.66e-01
GO:0044782 cilium organization	12	6.68e-02	3.06e-01	2.66e-01
GO:0030057 desmosome	12	6.82e-02	-3.04e-01	2.68e-01
GO:0050772 positive regulation of axonogenesis	12	6.91e-02	-3.03e-01	2.68e-01
GO:0060070 canonical Wnt signaling pathway	57	7.86e-05	-3.03e-01	3.15e-03
GO:0006979 response to oxidative stress	50	2.17e-04	3.02e-01	6.61e-03
GO:0034142 toll-like receptor 4 signaling pathway	15	4.28e-02	3.02e-01	2.11e-01
GO:0035035 histone acetyltransferase binding	12	7.01e-02	-3.02e-01	2.70e-01
GO:0031032 actomyosin structure organization	17	3.12e-02	-3.02e-01	1.77e-01
GO:0046718 symbiont entry into host cell	22	1.47e-02	-3.01e-01	1.13e-01
GO:0071333 cellular response to glucose stimulus	13	6.07e-02	-3.00e-01	2.56e-01
GO:0050661 NADP binding	15	4.44e-02	3.00e-01	2.14e-01
GO:0015035 protein-disulfide reductase activity	14	5.23e-02	3.00e-01	2.34e-01
GO:0003151 outflow tract morphogenesis	19	2.40e-02	-2.99e-01	1.52e-01
GO:0006695 cholesterol biosynthetic process	16	3.88e-02	2.98e-01	1.97e-01
GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	12	7.39e-02	-2.98e-01	2.80e-01
GO:0003925 G protein activity	18	2.87e-02	2.98e-01	1.74e-01
GO:0003281 ventricular septum development	15	4.59e-02	-2.98e-01	2.19e-01
GO:0042056 chemoattractant activity	11	8.79e-02	2.97e-01	3.07e-01
GO:0001917 photoreceptor inner segment	23	1.37e-02	2.97e-01	1.10e-01
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	67	2.74e-05	2.96e-01	1.27e-03
GO:0097352 autophagosome maturation	23	1.45e-02	2.95e-01	1.13e-01
GO:0005721 pericentric heterochromatin	18	3.09e-02	-2.94e-01	1.76e-01
GO:0005811 lipid droplet	42	9.95e-04	2.94e-01	2.01e-02
GO:0048026 positive regulation of mRNA splicing, via spliceosome	12	7.83e-02	-2.94e-01	2.88e-01
GO:0071108 protein K48-linked deubiquitination	15	4.91e-02	-2.93e-01	2.28e-01
GO:0030904 retromer complex	15	4.97e-02	2.93e-01	2.30e-01
GO:0090314 positive regulation of protein targeting to membrane	12	7.93e-02	2.93e-01	2.91e-01
GO:0007099 centriole replication	13	6.88e-02	2.92e-01	2.68e-01
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity	15	5.24e-02	-2.89e-01	2.34e-01
GO:0006622 protein targeting to lysosome	15	5.31e-02	2.88e-01	2.36e-01
GO:0042273 ribosomal large subunit biogenesis	22	1.96e-02	2.88e-01	1.36e-01
GO:0140588 chromatin looping	27	9.74e-03	-2.87e-01	8.99e-02
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment	35	3.29e-03	2.87e-01	4.46e-02
GO:0071363 cellular response to growth factor stimulus	19	3.04e-02	-2.87e-01	1.76e-01
GO:0060261 positive regulation of transcription initiation by RNA polymerase II	30	6.62e-03	-2.87e-01	7.35e-02
GO:0005743 mitochondrial inner membrane	180	3.77e-11	2.86e-01	1.11e-08
GO:0006623 protein targeting to vacuole	11	1.01e-01	-2.85e-01	3.37e-01
GO:0035025 positive regulation of Rho protein signal transduction	10	1.18e-01	-2.85e-01	3.74e-01
GO:0003713 transcription coactivator activity	128	2.71e-08	-2.85e-01	2.82e-06
GO:0017022 myosin binding	11	1.03e-01	-2.84e-01	3.40e-01
GO:0030150 protein import into mitochondrial matrix	12	8.86e-02	2.84e-01	3.08e-01
GO:0000422 autophagy of mitochondrion	14	6.64e-02	2.83e-01	2.66e-01
GO:0006633 fatty acid biosynthetic process	21	2.48e-02	2.83e-01	1.56e-01
GO:0003777 microtubule motor activity	23	1.89e-02	-2.83e-01	1.33e-01
GO:0061024 membrane organization	13	7.87e-02	2.82e-01	2.89e-01
GO:0051537 2 iron, 2 sulfur cluster binding	17	4.45e-02	2.81e-01	2.14e-01
GO:0016282 eukaryotic 43S preinitiation complex	14	6.87e-02	2.81e-01	2.68e-01
GO:0004402 histone acetyltransferase activity	11	1.08e-01	-2.80e-01	3.51e-01
GO:0097730 non-motile cilium	14	7.03e-02	2.79e-01	2.70e-01
GO:0051592 response to calcium ion	20	3.08e-02	2.79e-01	1.76e-01
GO:0000792 heterochromatin	19	3.58e-02	-2.78e-01	1.88e-01
GO:1904262 negative regulation of TORC1 signaling	28	1.09e-02	2.78e-01	9.44e-02
GO:0012506 vesicle membrane	16	5.43e-02	2.78e-01	2.38e-01
GO:0035269 protein O-linked mannosylation	13	8.33e-02	-2.77e-01	2.99e-01
GO:0005604 basement membrane	43	1.68e-03	-2.77e-01	2.84e-02
GO:0046966 nuclear thyroid hormone receptor binding	15	6.34e-02	-2.77e-01	2.62e-01
GO:0045815 transcription initiation-coupled chromatin remodeling	20	3.22e-02	-2.77e-01	1.80e-01
GO:0001649 osteoblast differentiation	39	2.83e-03	-2.76e-01	4.12e-02
GO:0051491 positive regulation of filopodium assembly	14	7.66e-02	-2.73e-01	2.84e-01
GO:0045332 phospholipid translocation	16	5.86e-02	2.73e-01	2.49e-01
GO:0035613 RNA stem-loop binding	11	1.17e-01	-2.73e-01	3.72e-01
GO:0050770 regulation of axonogenesis	13	8.85e-02	-2.73e-01	3.08e-01
GO:2001235 positive regulation of apoptotic signaling pathway	17	5.16e-02	2.73e-01	2.33e-01
GO:0061512 protein localization to cilium	22	2.69e-02	2.73e-01	1.65e-01
GO:0051480 regulation of cytosolic calcium ion concentration	13	8.93e-02	2.72e-01	3.09e-01
GO:0015914 phospholipid transport	26	1.72e-02	2.70e-01	1.25e-01
GO:0000400 four-way junction DNA binding	14	8.07e-02	2.70e-01	2.94e-01
GO:0003682 chromatin binding	238	8.74e-13	-2.70e-01	3.85e-10
GO:0000045 autophagosome assembly	52	7.84e-04	2.69e-01	1.75e-02
GO:0001671 ATPase activator activity	18	4.81e-02	2.69e-01	2.25e-01
GO:0001750 photoreceptor outer segment	24	2.26e-02	2.69e-01	1.49e-01
GO:0005484 SNAP receptor activity	26	1.81e-02	2.68e-01	1.30e-01
GO:0006936 muscle contraction	11	1.24e-01	-2.68e-01	3.81e-01
GO:0071526 semaphorin-plexin signaling pathway	25	2.09e-02	-2.67e-01	1.43e-01
GO:0008033 tRNA processing	15	7.46e-02	2.66e-01	2.81e-01
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	17	5.78e-02	-2.66e-01	2.46e-01
GO:0002039 p53 binding	44	2.30e-03	-2.66e-01	3.62e-02
GO:0000242 pericentriolar material	14	8.55e-02	-2.66e-01	3.03e-01
GO:0030020 extracellular matrix structural constituent conferring tensile strength	16	6.60e-02	2.66e-01	2.66e-01
GO:0006351 DNA-templated transcription	36	5.94e-03	-2.65e-01	6.96e-02
GO:0006413 translational initiation	30	1.23e-02	2.64e-01	1.03e-01
GO:1903543 positive regulation of exosomal secretion	10	1.48e-01	2.64e-01	4.25e-01
GO:0150052 regulation of postsynapse assembly	12	1.14e-01	-2.63e-01	3.66e-01
GO:0007095 mitotic G2 DNA damage checkpoint signaling	30	1.28e-02	-2.63e-01	1.06e-01
GO:0008327 methyl-CpG binding	16	6.91e-02	-2.63e-01	2.68e-01
GO:0001221 transcription coregulator binding	17	6.24e-02	-2.61e-01	2.60e-01
GO:0003714 transcription corepressor activity	101	5.92e-06	-2.61e-01	3.60e-04
GO:0046854 phosphatidylinositol phosphate biosynthetic process	18	5.54e-02	-2.61e-01	2.41e-01
GO:0008139 nuclear localization sequence binding	14	9.11e-02	-2.61e-01	3.14e-01
GO:0030018 Z disc	50	1.43e-03	-2.61e-01	2.50e-02
GO:0070403 NAD+ binding	11	1.36e-01	2.60e-01	4.00e-01
GO:1905515 non-motile cilium assembly	39	5.04e-03	2.60e-01	6.26e-02
GO:0035267 NuA4 histone acetyltransferase complex	18	5.66e-02	-2.60e-01	2.44e-01
GO:2000042 negative regulation of double-strand break repair via homologous recombination	16	7.31e-02	-2.59e-01	2.78e-01
GO:0008233 peptidase activity	10	1.57e-01	2.59e-01	4.30e-01
GO:0045070 positive regulation of viral genome replication	19	5.13e-02	-2.58e-01	2.33e-01
GO:0016460 myosin II complex	12	1.22e-01	-2.58e-01	3.77e-01
GO:0015813 L-glutamate transmembrane transport	11	1.41e-01	-2.56e-01	4.11e-01
GO:0007229 integrin-mediated signaling pathway	44	3.26e-03	-2.56e-01	4.46e-02
GO:0007411 axon guidance	79	8.35e-05	-2.56e-01	3.27e-03
GO:0030968 endoplasmic reticulum unfolded protein response	30	1.53e-02	2.56e-01	1.17e-01
GO:0140584 chromatin extrusion motor activity	23	3.39e-02	-2.56e-01	1.84e-01
GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity	23	3.39e-02	-2.56e-01	1.84e-01
GO:0140849 ATP-dependent H2AZ histone chaperone activity	23	3.39e-02	-2.56e-01	1.84e-01
GO:0035102 PRC1 complex	12	1.26e-01	-2.55e-01	3.84e-01
GO:0035023 regulation of Rho protein signal transduction	16	7.83e-02	-2.54e-01	2.88e-01
GO:0015629 actin cytoskeleton	113	3.10e-06	-2.54e-01	2.20e-04
GO:0070971 endoplasmic reticulum exit site	19	5.52e-02	2.54e-01	2.41e-01
GO:0006487 protein N-linked glycosylation	29	1.81e-02	2.54e-01	1.30e-01
GO:0003743 translation initiation factor activity	39	6.22e-03	2.53e-01	7.12e-02
GO:0061775 cohesin loader activity	24	3.20e-02	-2.53e-01	1.80e-01
GO:0036064 ciliary basal body	102	1.10e-05	2.52e-01	6.26e-04
GO:0030295 protein kinase activator activity	21	4.60e-02	-2.52e-01	2.19e-01
GO:0045672 positive regulation of osteoclast differentiation	11	1.50e-01	-2.51e-01	4.25e-01
GO:0001530 lipopolysaccharide binding	13	1.17e-01	2.51e-01	3.72e-01
GO:0060173 limb development	24	3.38e-02	-2.50e-01	1.84e-01
GO:0033209 tumor necrosis factor-mediated signaling pathway	15	9.38e-02	-2.50e-01	3.20e-01
GO:0004888 transmembrane signaling receptor activity	23	3.80e-02	2.50e-01	1.96e-01
GO:0042407 cristae formation	11	1.51e-01	2.50e-01	4.25e-01
GO:0043565 sequence-specific DNA binding	57	1.12e-03	-2.50e-01	2.13e-02
GO:0001676 long-chain fatty acid metabolic process	11	1.54e-01	2.49e-01	4.25e-01
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific	113	5.28e-06	-2.48e-01	3.33e-04
GO:0097546 ciliary base	17	7.69e-02	2.48e-01	2.85e-01
GO:0016829 lyase activity	15	9.73e-02	2.47e-01	3.28e-01
GO:0030514 negative regulation of BMP signaling pathway	26	2.94e-02	-2.47e-01	1.76e-01
GO:0031941 filamentous actin	18	7.03e-02	-2.46e-01	2.70e-01
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	21	5.14e-02	-2.46e-01	2.33e-01
GO:0097602 cullin family protein binding	16	8.91e-02	2.46e-01	3.09e-01
GO:0001516 prostaglandin biosynthetic process	10	1.80e-01	2.45e-01	4.61e-01
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	13	1.26e-01	2.45e-01	3.84e-01
GO:0032211 negative regulation of telomere maintenance via telomerase	10	1.81e-01	-2.45e-01	4.61e-01
GO:0006891 intra-Golgi vesicle-mediated transport	19	6.52e-02	2.44e-01	2.66e-01
GO:0042789 mRNA transcription by RNA polymerase II	27	2.84e-02	-2.44e-01	1.73e-01
GO:0035869 ciliary transition zone	22	4.83e-02	2.43e-01	2.25e-01
GO:0001756 somitogenesis	25	3.56e-02	-2.43e-01	1.88e-01
GO:2000377 regulation of reactive oxygen species metabolic process	10	1.85e-01	2.42e-01	4.68e-01
GO:0007417 central nervous system development	41	7.31e-03	-2.42e-01	7.73e-02
GO:0033962 P-body assembly	14	1.17e-01	-2.42e-01	3.72e-01
GO:0009953 dorsal/ventral pattern formation	16	9.44e-02	-2.42e-01	3.21e-01
GO:0060828 regulation of canonical Wnt signaling pathway	18	7.61e-02	-2.42e-01	2.83e-01
GO:0031982 vesicle	27	3.01e-02	2.41e-01	1.76e-01
GO:0015701 bicarbonate transport	11	1.67e-01	-2.41e-01	4.40e-01
GO:0005667 transcription regulator complex	92	6.86e-05	-2.40e-01	2.88e-03
GO:0007628 adult walking behavior	12	1.50e-01	-2.40e-01	4.25e-01
GO:0045453 bone resorption	12	1.50e-01	-2.40e-01	4.25e-01
GO:0009954 proximal/distal pattern formation	14	1.20e-01	-2.40e-01	3.76e-01
GO:0070498 interleukin-1-mediated signaling pathway	11	1.70e-01	2.39e-01	4.43e-01
GO:0010212 response to ionizing radiation	24	4.28e-02	-2.39e-01	2.11e-01
GO:0060412 ventricular septum morphogenesis	18	7.94e-02	-2.39e-01	2.91e-01
GO:0045454 cell redox homeostasis	20	6.48e-02	2.39e-01	2.66e-01
GO:0008320 protein transmembrane transporter activity	11	1.71e-01	2.38e-01	4.45e-01
GO:0016529 sarcoplasmic reticulum	14	1.23e-01	-2.38e-01	3.80e-01
GO:0070888 E-box binding	21	5.96e-02	-2.38e-01	2.52e-01
GO:0034446 substrate adhesion-dependent cell spreading	33	1.85e-02	-2.37e-01	1.31e-01
GO:0005021 vascular endothelial growth factor receptor activity	16	1.03e-01	-2.36e-01	3.40e-01
GO:0000146 microfilament motor activity	19	7.53e-02	-2.36e-01	2.82e-01
GO:0000149 SNARE binding	31	2.32e-02	2.36e-01	1.49e-01
GO:0030134 COPII-coated ER to Golgi transport vesicle	21	6.16e-02	2.36e-01	2.58e-01
GO:0050796 regulation of insulin secretion	12	1.58e-01	2.36e-01	4.30e-01
GO:0008277 regulation of G protein-coupled receptor signaling pathway	16	1.04e-01	2.35e-01	3.41e-01
GO:0048384 retinoic acid receptor signaling pathway	11	1.78e-01	-2.34e-01	4.60e-01
GO:0032543 mitochondrial translation	22	5.71e-02	2.34e-01	2.44e-01
GO:0060976 coronary vasculature development	17	9.49e-02	-2.34e-01	3.22e-01
GO:0030665 clathrin-coated vesicle membrane	11	1.80e-01	2.34e-01	4.61e-01
GO:0000421 autophagosome membrane	23	5.29e-02	2.33e-01	2.35e-01
GO:0021915 neural tube development	17	9.66e-02	-2.33e-01	3.27e-01
GO:0030426 growth cone	41	9.94e-03	-2.33e-01	9.00e-02
GO:0030017 sarcomere	13	1.47e-01	2.33e-01	4.22e-01
GO:0140672 ATAC complex	11	1.83e-01	-2.32e-01	4.64e-01
GO:0006338 chromatin remodeling	250	2.91e-10	-2.32e-01	5.13e-08
GO:0007155 cell adhesion	106	3.81e-05	-2.32e-01	1.68e-03
GO:0042572 retinol metabolic process	12	1.65e-01	2.32e-01	4.39e-01
GO:0034097 response to cytokine	12	1.65e-01	-2.31e-01	4.39e-01
GO:0050839 cell adhesion molecule binding	21	6.67e-02	-2.31e-01	2.66e-01
GO:0048147 negative regulation of fibroblast proliferation	15	1.21e-01	-2.31e-01	3.76e-01
GO:0005666 RNA polymerase III complex	12	1.66e-01	2.31e-01	4.40e-01
GO:0005758 mitochondrial intermembrane space	47	6.28e-03	2.31e-01	7.14e-02
GO:0005762 mitochondrial large ribosomal subunit	38	1.40e-02	2.31e-01	1.11e-01
GO:0048009 insulin-like growth factor receptor signaling pathway	32	2.43e-02	-2.30e-01	1.53e-01
GO:0071897 DNA biosynthetic process	12	1.68e-01	-2.30e-01	4.41e-01
GO:0000381 regulation of alternative mRNA splicing, via spliceosome	31	2.68e-02	-2.30e-01	1.65e-01
GO:0001654 eye development	17	1.02e-01	-2.29e-01	3.39e-01
GO:0042826 histone deacetylase binding	66	1.31e-03	-2.29e-01	2.37e-02
GO:0030182 neuron differentiation	56	3.08e-03	-2.29e-01	4.31e-02
GO:0098761 cellular response to interleukin-7	10	2.10e-01	-2.29e-01	5.05e-01
GO:0005902 microvillus	28	3.70e-02	2.28e-01	1.92e-01
GO:0005774 vacuolar membrane	10	2.13e-01	2.28e-01	5.09e-01
GO:0048741 skeletal muscle fiber development	16	1.15e-01	-2.28e-01	3.68e-01
GO:0003824 catalytic activity	10	2.13e-01	2.27e-01	5.10e-01
GO:0030141 secretory granule	19	8.65e-02	2.27e-01	3.04e-01
GO:0001558 regulation of cell growth	24	5.41e-02	-2.27e-01	2.38e-01
GO:0005791 rough endoplasmic reticulum	12	1.73e-01	-2.27e-01	4.49e-01
GO:0004867 serine-type endopeptidase inhibitor activity	22	6.65e-02	-2.26e-01	2.66e-01
GO:0099149 regulation of postsynaptic neurotransmitter receptor internalization	12	1.75e-01	2.26e-01	4.53e-01
GO:0010507 negative regulation of autophagy	23	6.12e-02	-2.26e-01	2.57e-01
GO:0065003 protein-containing complex assembly	37	1.78e-02	-2.25e-01	1.29e-01
GO:0048008 platelet-derived growth factor receptor signaling pathway	17	1.09e-01	-2.25e-01	3.53e-01
GO:0031012 extracellular matrix	87	2.97e-04	-2.25e-01	8.24e-03
GO:0045599 negative regulation of fat cell differentiation	21	7.49e-02	-2.25e-01	2.82e-01
GO:0005245 voltage-gated calcium channel activity	12	1.79e-01	2.24e-01	4.60e-01
GO:0030165 PDZ domain binding	29	3.67e-02	-2.24e-01	1.91e-01
GO:0034394 protein localization to cell surface	17	1.12e-01	-2.22e-01	3.61e-01
GO:0071013 catalytic step 2 spliceosome	52	5.71e-03	-2.22e-01	6.85e-02
GO:0042393 histone binding	94	2.09e-04	-2.22e-01	6.46e-03
GO:0045931 positive regulation of mitotic cell cycle	14	1.53e-01	2.21e-01	4.25e-01
GO:2000773 negative regulation of cellular senescence	12	1.85e-01	2.21e-01	4.69e-01
GO:0030286 dynein complex	10	2.27e-01	2.20e-01	5.23e-01
GO:0070064 proline-rich region binding	10	2.28e-01	-2.20e-01	5.23e-01
GO:0010719 negative regulation of epithelial to mesenchymal transition	16	1.27e-01	-2.20e-01	3.87e-01
GO:0004860 protein kinase inhibitor activity	19	9.73e-02	2.20e-01	3.28e-01
GO:0019827 stem cell population maintenance	21	8.16e-02	-2.20e-01	2.96e-01
GO:0000791 euchromatin	29	4.08e-02	-2.20e-01	2.04e-01
GO:0051287 NAD binding	20	8.94e-02	2.19e-01	3.09e-01
GO:0007601 visual perception	38	1.93e-02	2.19e-01	1.34e-01
GO:0033173 calcineurin-NFAT signaling cascade	10	2.31e-01	-2.19e-01	5.23e-01
GO:0016180 snRNA processing	10	2.32e-01	-2.19e-01	5.23e-01
GO:0040029 epigenetic regulation of gene expression	19	9.99e-02	-2.18e-01	3.34e-01
GO:0030863 cortical cytoskeleton	10	2.33e-01	2.18e-01	5.23e-01
GO:0030136 clathrin-coated vesicle	29	4.31e-02	2.17e-01	2.12e-01
GO:0000774 adenyl-nucleotide exchange factor activity	12	1.93e-01	-2.17e-01	4.79e-01
GO:0035994 response to muscle stretch	10	2.37e-01	-2.16e-01	5.27e-01
GO:0006355 regulation of DNA-templated transcription	159	2.80e-06	-2.16e-01	2.15e-04
GO:0070507 regulation of microtubule cytoskeleton organization	14	1.63e-01	2.16e-01	4.36e-01
GO:0007076 mitotic chromosome condensation	10	2.38e-01	-2.16e-01	5.28e-01
GO:0000132 establishment of mitotic spindle orientation	26	5.72e-02	2.16e-01	2.44e-01
GO:0031397 negative regulation of protein ubiquitination	33	3.25e-02	2.15e-01	1.81e-01
GO:0007218 neuropeptide signaling pathway	14	1.64e-01	2.15e-01	4.38e-01
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	11	2.17e-01	-2.15e-01	5.12e-01
GO:0004857 enzyme inhibitor activity	12	1.98e-01	-2.15e-01	4.85e-01
GO:0071005 U2-type precatalytic spliceosome	31	3.88e-02	-2.14e-01	1.97e-01
GO:0099560 synaptic membrane adhesion	14	1.65e-01	-2.14e-01	4.39e-01
GO:0006406 mRNA export from nucleus	28	5.00e-02	-2.14e-01	2.31e-01
GO:0046847 filopodium assembly	11	2.20e-01	2.14e-01	5.16e-01
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT	11	2.20e-01	2.14e-01	5.16e-01
GO:0000266 mitochondrial fission	10	2.42e-01	2.14e-01	5.34e-01
GO:0035198 miRNA binding	20	9.84e-02	-2.14e-01	3.29e-01
GO:0042981 regulation of apoptotic process	55	6.19e-03	-2.14e-01	7.12e-02
GO:0000786 nucleosome	16	1.41e-01	-2.12e-01	4.11e-01
GO:0043024 ribosomal small subunit binding	13	1.85e-01	-2.12e-01	4.68e-01
GO:0006346 DNA methylation-dependent constitutive heterochromatin formation	10	2.46e-01	-2.12e-01	5.37e-01
GO:0000785 chromatin	241	1.56e-08	-2.12e-01	1.72e-06
GO:0035770 ribonucleoprotein granule	13	1.86e-01	-2.12e-01	4.69e-01
GO:0097060 synaptic membrane	12	2.05e-01	-2.11e-01	4.95e-01
GO:1904115 axon cytoplasm	25	6.78e-02	2.11e-01	2.67e-01
GO:0001708 cell fate specification	12	2.06e-01	-2.11e-01	4.96e-01
GO:0003729 mRNA binding	145	1.20e-05	-2.11e-01	6.61e-04
GO:0042995 cell projection	53	8.10e-03	-2.10e-01	8.02e-02
GO:0005782 peroxisomal matrix	10	2.50e-01	2.10e-01	5.42e-01
GO:0000387 spliceosomal snRNP assembly	17	1.35e-01	2.09e-01	3.99e-01
GO:0071339 MLL1 complex	18	1.24e-01	-2.09e-01	3.81e-01
GO:0045773 positive regulation of axon extension	10	2.52e-01	-2.09e-01	5.44e-01
GO:0071300 cellular response to retinoic acid	17	1.36e-01	-2.09e-01	4.00e-01
GO:0046488 phosphatidylinositol metabolic process	13	1.92e-01	-2.09e-01	4.78e-01
GO:0000976 transcription cis-regulatory region binding	54	8.07e-03	-2.09e-01	8.02e-02
GO:0030658 transport vesicle membrane	13	1.93e-01	2.08e-01	4.79e-01
GO:0003725 double-stranded RNA binding	43	1.81e-02	-2.08e-01	1.30e-01
GO:0004683 calcium/calmodulin-dependent protein kinase activity	11	2.33e-01	2.08e-01	5.23e-01
GO:0051017 actin filament bundle assembly	13	1.95e-01	-2.08e-01	4.82e-01
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II	11	2.33e-01	-2.08e-01	5.23e-01
GO:0097718 disordered domain specific binding	15	1.64e-01	-2.08e-01	4.38e-01
GO:0002682 regulation of immune system process	11	2.33e-01	-2.08e-01	5.23e-01
GO:0048568 embryonic organ development	15	1.65e-01	-2.07e-01	4.39e-01
GO:0020037 heme binding	52	9.92e-03	2.07e-01	9.00e-02
GO:0003007 heart morphogenesis	15	1.66e-01	-2.07e-01	4.39e-01
GO:0003899 DNA-directed 5’-3’ RNA polymerase activity	10	2.58e-01	-2.07e-01	5.47e-01
GO:0051489 regulation of filopodium assembly	10	2.58e-01	2.06e-01	5.47e-01
GO:0001889 liver development	30	5.05e-02	-2.06e-01	2.31e-01
GO:0005912 adherens junction	70	2.85e-03	-2.06e-01	4.12e-02
GO:0042102 positive regulation of T cell proliferation	10	2.60e-01	-2.06e-01	5.49e-01
GO:0036211 protein modification process	16	1.54e-01	2.06e-01	4.26e-01
GO:0048870 cell motility	12	2.18e-01	-2.06e-01	5.13e-01
GO:0031210 phosphatidylcholine binding	18	1.31e-01	2.05e-01	3.92e-01
GO:0034198 cellular response to amino acid starvation	31	4.83e-02	2.05e-01	2.25e-01
GO:0030855 epithelial cell differentiation	29	5.69e-02	2.04e-01	2.44e-01
GO:0000723 telomere maintenance	29	5.71e-02	-2.04e-01	2.44e-01
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading	24	8.40e-02	-2.04e-01	3.00e-01
GO:0010508 positive regulation of autophagy	39	2.79e-02	2.03e-01	1.71e-01
GO:0006654 phosphatidic acid biosynthetic process	12	2.23e-01	2.03e-01	5.20e-01
GO:0007399 nervous system development	87	1.06e-03	-2.03e-01	2.05e-02
GO:0060236 regulation of mitotic spindle organization	12	2.23e-01	-2.03e-01	5.20e-01
GO:0050750 low-density lipoprotein particle receptor binding	12	2.23e-01	-2.03e-01	5.20e-01
GO:0005085 guanyl-nucleotide exchange factor activity	143	2.84e-05	-2.03e-01	1.29e-03
GO:0042277 peptide binding	10	2.68e-01	-2.02e-01	5.58e-01
GO:0016491 oxidoreductase activity	47	1.66e-02	2.02e-01	1.23e-01
GO:0019216 regulation of lipid metabolic process	10	2.69e-01	-2.02e-01	5.59e-01
GO:0001568 blood vessel development	18	1.39e-01	-2.02e-01	4.07e-01
GO:0004521 RNA endonuclease activity	20	1.19e-01	2.01e-01	3.76e-01
GO:0000939 inner kinetochore	10	2.72e-01	2.01e-01	5.61e-01
GO:0000902 cell morphogenesis	55	1.01e-02	-2.01e-01	9.00e-02
GO:0031526 brush border membrane	12	2.29e-01	-2.01e-01	5.23e-01
GO:0001570 vasculogenesis	26	7.71e-02	-2.00e-01	2.85e-01
GO:0003712 transcription coregulator activity	75	2.75e-03	-2.00e-01	4.07e-02
GO:0071353 cellular response to interleukin-4	10	2.73e-01	2.00e-01	5.64e-01
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules	36	3.81e-02	-2.00e-01	1.96e-01
GO:0030027 lamellipodium	91	9.99e-04	-2.00e-01	2.01e-02
GO:0035329 hippo signaling	17	1.54e-01	-2.00e-01	4.25e-01
GO:0035371 microtubule plus-end	12	2.31e-01	-2.00e-01	5.23e-01
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle	15	1.82e-01	-1.99e-01	4.63e-01
GO:0031514 motile cilium	38	3.37e-02	1.99e-01	1.84e-01
GO:0048813 dendrite morphogenesis	20	1.23e-01	1.99e-01	3.80e-01
GO:0030036 actin cytoskeleton organization	107	3.90e-04	-1.99e-01	9.82e-03
GO:0030054 cell junction	53	1.24e-02	-1.99e-01	1.04e-01
GO:0048027 mRNA 5’-UTR binding	19	1.34e-01	1.99e-01	3.97e-01
GO:0045995 regulation of embryonic development	27	7.45e-02	-1.98e-01	2.81e-01
GO:0060382 regulation of DNA strand elongation	10	2.78e-01	-1.98e-01	5.69e-01
GO:0009749 response to glucose	13	2.17e-01	-1.98e-01	5.11e-01
GO:0032757 positive regulation of interleukin-8 production	17	1.58e-01	1.98e-01	4.30e-01
GO:0017147 Wnt-protein binding	17	1.58e-01	-1.98e-01	4.30e-01
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway	11	2.56e-01	-1.98e-01	5.47e-01
GO:0002376 immune system process	12	2.36e-01	1.98e-01	5.26e-01
GO:0007409 axonogenesis	40	3.07e-02	-1.98e-01	1.76e-01
GO:0007010 cytoskeleton organization	51	1.47e-02	-1.98e-01	1.13e-01
GO:0007416 synapse assembly	23	1.02e-01	-1.97e-01	3.38e-01
GO:0009791 post-embryonic development	36	4.07e-02	-1.97e-01	2.04e-01
GO:0005009 insulin receptor activity	15	1.87e-01	-1.97e-01	4.69e-01
GO:0000781 chromosome, telomeric region	75	3.37e-03	-1.96e-01	4.54e-02
GO:0000307 cyclin-dependent protein kinase holoenzyme complex	21	1.20e-01	1.96e-01	3.76e-01
GO:0030220 platelet formation	11	2.61e-01	-1.96e-01	5.50e-01
GO:0036342 post-anal tail morphogenesis	11	2.61e-01	-1.96e-01	5.50e-01
GO:0007030 Golgi organization	63	7.32e-03	1.95e-01	7.73e-02
GO:0048306 calcium-dependent protein binding	20	1.31e-01	1.95e-01	3.91e-01
GO:0001772 immunological synapse	23	1.07e-01	1.94e-01	3.49e-01
GO:0006261 DNA-templated DNA replication	18	1.54e-01	-1.94e-01	4.25e-01
GO:0045595 regulation of cell differentiation	13	2.26e-01	-1.94e-01	5.23e-01
GO:0006260 DNA replication	34	5.03e-02	-1.94e-01	2.31e-01
GO:0046835 carbohydrate phosphorylation	20	1.34e-01	-1.94e-01	3.97e-01
GO:0019221 cytokine-mediated signaling pathway	44	2.63e-02	1.94e-01	1.64e-01
GO:0005518 collagen binding	34	5.08e-02	-1.94e-01	2.32e-01
GO:0016363 nuclear matrix	46	2.32e-02	-1.94e-01	1.49e-01
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	13	2.27e-01	-1.93e-01	5.23e-01
GO:0031462 Cul2-RING ubiquitin ligase complex	15	1.95e-01	-1.93e-01	4.82e-01
GO:0046332 SMAD binding	23	1.09e-01	-1.93e-01	3.53e-01
GO:0030946 protein tyrosine phosphatase activity, metal-dependent	15	1.96e-01	-1.93e-01	4.82e-01
GO:0140793 histone H2AXY142 phosphatase activity	15	1.96e-01	-1.93e-01	4.82e-01
GO:0030544 Hsp70 protein binding	29	7.29e-02	1.92e-01	2.78e-01
GO:0034704 calcium channel complex	10	2.93e-01	1.92e-01	5.83e-01
GO:0042060 wound healing	29	7.38e-02	-1.92e-01	2.80e-01
GO:0010494 cytoplasmic stress granule	58	1.18e-02	-1.91e-01	1.01e-01
GO:0032481 positive regulation of type I interferon production	18	1.61e-01	1.91e-01	4.34e-01
GO:0080025 phosphatidylinositol-3,5-bisphosphate binding	15	2.01e-01	1.91e-01	4.89e-01
GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity	13	2.34e-01	-1.91e-01	5.23e-01
GO:0015297 antiporter activity	18	1.61e-01	1.91e-01	4.35e-01
GO:0032008 positive regulation of TOR signaling	12	2.53e-01	1.90e-01	5.46e-01
GO:0042098 T cell proliferation	16	1.88e-01	-1.90e-01	4.72e-01
GO:0030424 axon	121	3.12e-04	-1.90e-01	8.34e-03
GO:0046677 response to antibiotic	13	2.37e-01	1.90e-01	5.27e-01
GO:0050660 flavin adenine dinucleotide binding	33	5.98e-02	1.89e-01	2.52e-01
GO:0032922 circadian regulation of gene expression	34	5.62e-02	-1.89e-01	2.44e-01
GO:0051117 ATPase binding	44	2.99e-02	1.89e-01	1.76e-01
GO:0032508 DNA duplex unwinding	44	3.02e-02	-1.89e-01	1.76e-01
GO:0070402 NADPH binding	10	3.01e-01	1.89e-01	5.96e-01
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding	84	2.81e-03	-1.89e-01	4.12e-02
GO:0048538 thymus development	22	1.25e-01	-1.89e-01	3.84e-01
GO:0050679 positive regulation of epithelial cell proliferation	20	1.44e-01	-1.89e-01	4.17e-01
GO:0140662 ATP-dependent protein folding chaperone	23	1.17e-01	-1.89e-01	3.72e-01
GO:0045648 positive regulation of erythrocyte differentiation	18	1.69e-01	-1.87e-01	4.42e-01
GO:0090090 negative regulation of canonical Wnt signaling pathway	70	6.82e-03	-1.87e-01	7.38e-02
GO:0031507 heterochromatin formation	27	9.30e-02	-1.87e-01	3.18e-01
GO:0061436 establishment of skin barrier	13	2.44e-01	-1.87e-01	5.36e-01
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific	346	3.06e-09	-1.86e-01	3.85e-07
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation	14	2.29e-01	-1.86e-01	5.23e-01
GO:0007612 learning	13	2.47e-01	-1.86e-01	5.38e-01
GO:0061157 mRNA destabilization	12	2.66e-01	-1.85e-01	5.58e-01
GO:1905168 positive regulation of double-strand break repair via homologous recombination	25	1.10e-01	-1.85e-01	3.54e-01
GO:0035019 somatic stem cell population maintenance	31	7.57e-02	-1.84e-01	2.82e-01
GO:0038202 TORC1 signaling	12	2.70e-01	1.84e-01	5.59e-01
GO:0070936 protein K48-linked ubiquitination	68	9.05e-03	1.83e-01	8.63e-02
GO:0005929 cilium	78	5.27e-03	1.83e-01	6.49e-02
GO:0090128 regulation of synapse maturation	10	3.18e-01	1.82e-01	6.12e-01
GO:0043484 regulation of RNA splicing	23	1.31e-01	-1.82e-01	3.91e-01
GO:0043029 T cell homeostasis	13	2.56e-01	-1.82e-01	5.47e-01
GO:0000122 negative regulation of transcription by RNA polymerase II	394	7.07e-10	-1.82e-01	1.13e-07
GO:0031334 positive regulation of protein-containing complex assembly	17	1.95e-01	1.82e-01	4.82e-01
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding	392	9.01e-10	-1.81e-01	1.32e-07
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway	13	2.58e-01	-1.81e-01	5.47e-01
GO:0009410 response to xenobiotic stimulus	46	3.38e-02	-1.81e-01	1.84e-01
GO:0010569 regulation of double-strand break repair via homologous recombination	10	3.22e-01	-1.81e-01	6.18e-01
GO:0003779 actin binding	140	2.29e-04	-1.81e-01	6.73e-03
GO:0006631 fatty acid metabolic process	34	6.85e-02	1.81e-01	2.68e-01
GO:0045494 photoreceptor cell maintenance	25	1.19e-01	1.80e-01	3.76e-01
GO:0071407 cellular response to organic cyclic compound	11	3.02e-01	-1.80e-01	5.96e-01
GO:0009952 anterior/posterior pattern specification	42	4.45e-02	-1.79e-01	2.14e-01
GO:0031252 cell leading edge	19	1.76e-01	-1.79e-01	4.55e-01
GO:0043588 skin development	24	1.29e-01	-1.79e-01	3.88e-01
GO:0008047 enzyme activator activity	15	2.30e-01	-1.79e-01	5.23e-01
GO:0030425 dendrite	133	3.81e-04	-1.79e-01	9.74e-03
GO:1990782 protein tyrosine kinase binding	15	2.31e-01	-1.78e-01	5.23e-01
GO:0006906 vesicle fusion	15	2.32e-01	1.78e-01	5.23e-01
GO:0004896 cytokine receptor activity	19	1.79e-01	1.78e-01	4.60e-01
GO:0000118 histone deacetylase complex	22	1.50e-01	-1.78e-01	4.25e-01
GO:0030170 pyridoxal phosphate binding	32	8.28e-02	1.77e-01	2.98e-01
GO:0008023 transcription elongation factor complex	14	2.52e-01	-1.77e-01	5.43e-01
GO:0008360 regulation of cell shape	61	1.70e-02	-1.77e-01	1.25e-01
GO:0043531 ADP binding	20	1.72e-01	-1.77e-01	4.46e-01
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	32	8.43e-02	1.76e-01	3.01e-01
GO:0045739 positive regulation of DNA repair	20	1.72e-01	-1.76e-01	4.47e-01
GO:0016459 myosin complex	24	1.35e-01	-1.76e-01	3.99e-01
GO:0140664 ATP-dependent DNA damage sensor activity	14	2.54e-01	1.76e-01	5.46e-01
GO:0007507 heart development	80	6.56e-03	-1.76e-01	7.33e-02
GO:1900182 positive regulation of protein localization to nucleus	25	1.28e-01	-1.76e-01	3.88e-01
GO:0007029 endoplasmic reticulum organization	16	2.23e-01	1.76e-01	5.20e-01
GO:0051290 protein heterotetramerization	10	3.36e-01	-1.76e-01	6.33e-01
GO:0034332 adherens junction organization	12	2.92e-01	1.76e-01	5.82e-01
GO:1990837 sequence-specific double-stranded DNA binding	47	3.73e-02	-1.76e-01	1.93e-01
GO:0035979 histone H2AXS139 kinase activity	32	8.59e-02	-1.75e-01	3.03e-01
GO:0031175 neuron projection development	50	3.22e-02	-1.75e-01	1.80e-01
GO:0018279 protein N-linked glycosylation via asparagine	11	3.14e-01	1.75e-01	6.08e-01
GO:0045879 negative regulation of smoothened signaling pathway	15	2.41e-01	1.75e-01	5.34e-01
GO:0032570 response to progesterone	13	2.76e-01	-1.74e-01	5.69e-01
GO:0006325 chromatin organization	66	1.46e-02	-1.74e-01	1.13e-01
GO:0005178 integrin binding	65	1.54e-02	-1.74e-01	1.17e-01
GO:0043616 keratinocyte proliferation	11	3.19e-01	1.74e-01	6.12e-01
GO:0015485 cholesterol binding	29	1.06e-01	1.74e-01	3.47e-01
GO:0043153 entrainment of circadian clock by photoperiod	13	2.79e-01	-1.74e-01	5.69e-01
GO:0001764 neuron migration	38	6.45e-02	-1.73e-01	2.65e-01
GO:0035855 megakaryocyte development	10	3.43e-01	-1.73e-01	6.45e-01
GO:0005925 focal adhesion	113	1.53e-03	-1.73e-01	2.61e-02
GO:0030326 embryonic limb morphogenesis	14	2.63e-01	-1.73e-01	5.54e-01
GO:0015030 Cajal body	26	1.28e-01	-1.72e-01	3.88e-01
GO:0051959 dynein light intermediate chain binding	16	2.34e-01	-1.72e-01	5.23e-01
GO:0005200 structural constituent of cytoskeleton	27	1.22e-01	-1.72e-01	3.78e-01
GO:0031201 SNARE complex	33	8.77e-02	1.72e-01	3.07e-01
GO:0030507 spectrin binding	13	2.84e-01	-1.72e-01	5.75e-01
GO:0060041 retina development in camera-type eye	20	1.84e-01	-1.72e-01	4.66e-01
GO:0141198 protein branched polyubiquitination	13	2.84e-01	-1.72e-01	5.75e-01
GO:0031594 neuromuscular junction	34	8.34e-02	-1.72e-01	2.99e-01
GO:0007131 reciprocal meiotic recombination	12	3.04e-01	1.72e-01	5.99e-01
GO:0006886 intracellular protein transport	160	1.86e-04	1.71e-01	5.98e-03
GO:0140326 ATPase-coupled intramembrane lipid transporter activity	11	3.25e-01	1.71e-01	6.22e-01
GO:0090316 positive regulation of intracellular protein transport	14	2.67e-01	1.71e-01	5.58e-01
GO:0016525 negative regulation of angiogenesis	36	7.55e-02	-1.71e-01	2.82e-01
GO:0003700 DNA-binding transcription factor activity	79	8.61e-03	-1.71e-01	8.43e-02
GO:0005764 lysosome	132	7.04e-04	1.71e-01	1.61e-02
GO:0036297 interstrand cross-link repair	24	1.47e-01	1.71e-01	4.23e-01
GO:0001508 action potential	11	3.29e-01	-1.70e-01	6.27e-01
GO:0002224 toll-like receptor signaling pathway	15	2.54e-01	1.70e-01	5.46e-01
GO:0008380 RNA splicing	47	4.41e-02	-1.70e-01	2.14e-01
GO:0009060 aerobic respiration	10	3.53e-01	1.70e-01	6.52e-01
GO:0043687 post-translational protein modification	19	2.01e-01	1.70e-01	4.89e-01
GO:0051496 positive regulation of stress fiber assembly	31	1.03e-01	-1.69e-01	3.40e-01
GO:0005783 endoplasmic reticulum	433	1.84e-09	1.69e-01	2.50e-07
GO:0051302 regulation of cell division	11	3.31e-01	-1.69e-01	6.31e-01
GO:0007163 establishment or maintenance of cell polarity	13	2.92e-01	1.69e-01	5.82e-01
GO:0007596 blood coagulation	25	1.45e-01	1.68e-01	4.19e-01
GO:0004386 helicase activity	40	6.54e-02	-1.68e-01	2.66e-01
GO:0061744 motor behavior	16	2.44e-01	-1.68e-01	5.36e-01
GO:1990244 histone H2AT120 kinase activity	31	1.06e-01	-1.68e-01	3.47e-01
GO:0010761 fibroblast migration	10	3.60e-01	-1.67e-01	6.61e-01
GO:0048536 spleen development	23	1.67e-01	-1.66e-01	4.40e-01
GO:0070588 calcium ion transmembrane transport	45	5.44e-02	1.66e-01	2.38e-01
GO:0001678 intracellular glucose homeostasis	17	2.37e-01	-1.66e-01	5.27e-01
GO:0031122 cytoplasmic microtubule organization	28	1.30e-01	-1.65e-01	3.89e-01
GO:0008013 beta-catenin binding	46	5.24e-02	-1.65e-01	2.34e-01
GO:0007265 Ras protein signal transduction	37	8.19e-02	-1.65e-01	2.96e-01
GO:0006974 DNA damage response	120	1.78e-03	-1.65e-01	2.99e-02
GO:0050673 epithelial cell proliferation	19	2.13e-01	-1.65e-01	5.10e-01
GO:1901223 negative regulation of non-canonical NF-kappaB signal transduction	14	2.86e-01	1.65e-01	5.75e-01
GO:0030168 platelet activation	11	3.45e-01	-1.64e-01	6.48e-01
GO:0000139 Golgi membrane	261	5.12e-06	1.64e-01	3.33e-04
GO:0008333 endosome to lysosome transport	32	1.09e-01	1.64e-01	3.53e-01
GO:0005930 axoneme	47	5.22e-02	1.64e-01	2.34e-01
GO:0040018 positive regulation of multicellular organism growth	17	2.43e-01	-1.64e-01	5.34e-01
GO:0042162 telomeric DNA binding	20	2.05e-01	-1.64e-01	4.96e-01
GO:0043542 endothelial cell migration	13	3.07e-01	-1.64e-01	6.00e-01
GO:0071466 cellular response to xenobiotic stimulus	24	1.66e-01	-1.63e-01	4.40e-01
GO:0007267 cell-cell signaling	13	3.08e-01	-1.63e-01	6.01e-01
GO:0034451 centriolar satellite	72	1.67e-02	1.63e-01	1.24e-01
GO:0046875 ephrin receptor binding	17	2.44e-01	1.63e-01	5.36e-01
GO:0030308 negative regulation of cell growth	42	6.74e-02	-1.63e-01	2.67e-01
GO:0000932 P-body	60	2.90e-02	-1.63e-01	1.75e-01
GO:0045892 negative regulation of DNA-templated transcription	173	2.23e-04	-1.63e-01	6.65e-03
GO:0032956 regulation of actin cytoskeleton organization	37	8.65e-02	1.63e-01	3.04e-01
GO:0032007 negative regulation of TOR signaling	18	2.32e-01	1.63e-01	5.23e-01
GO:0007098 centrosome cycle	17	2.46e-01	1.63e-01	5.37e-01
GO:0003333 amino acid transmembrane transport	10	3.74e-01	-1.63e-01	6.70e-01
GO:0033617 mitochondrial cytochrome c oxidase assembly	13	3.11e-01	1.62e-01	6.04e-01
GO:0046716 muscle cell cellular homeostasis	15	2.78e-01	-1.62e-01	5.69e-01
GO:0016328 lateral plasma membrane	24	1.70e-01	-1.62e-01	4.44e-01
GO:0006635 fatty acid beta-oxidation	26	1.54e-01	1.62e-01	4.25e-01
GO:0045165 cell fate commitment	21	2.01e-01	-1.61e-01	4.89e-01
GO:0030317 flagellated sperm motility	28	1.40e-01	1.61e-01	4.09e-01
GO:0071782 endoplasmic reticulum tubular network	12	3.34e-01	-1.61e-01	6.33e-01
GO:0006396 RNA processing	21	2.01e-01	-1.61e-01	4.89e-01
GO:0005879 axonemal microtubule	10	3.78e-01	1.61e-01	6.71e-01
GO:0016607 nuclear speck	242	1.71e-05	-1.61e-01	8.85e-04
GO:0034063 stress granule assembly	21	2.02e-01	-1.61e-01	4.90e-01
GO:0014032 neural crest cell development	11	3.57e-01	1.61e-01	6.58e-01
GO:0060325 face morphogenesis	20	2.14e-01	-1.60e-01	5.11e-01
GO:0006357 regulation of transcription by RNA polymerase II	548	2.05e-10	-1.60e-01	4.52e-08
GO:0042307 positive regulation of protein import into nucleus	25	1.67e-01	-1.60e-01	4.40e-01
GO:0031491 nucleosome binding	25	1.69e-01	-1.59e-01	4.43e-01
GO:0045722 positive regulation of gluconeogenesis	10	3.85e-01	-1.59e-01	6.71e-01
GO:0048513 animal organ development	12	3.41e-01	1.59e-01	6.43e-01
GO:0046983 protein dimerization activity	70	2.18e-02	-1.59e-01	1.45e-01
GO:0032722 positive regulation of chemokine production	11	3.63e-01	1.58e-01	6.61e-01
GO:0022904 respiratory electron transport chain	14	3.05e-01	1.58e-01	6.00e-01
GO:0005814 centriole	91	9.16e-03	1.58e-01	8.64e-02
GO:0044344 cellular response to fibroblast growth factor stimulus	10	3.87e-01	1.58e-01	6.71e-01
GO:0072593 reactive oxygen species metabolic process	15	2.90e-01	1.58e-01	5.81e-01
GO:2000378 negative regulation of reactive oxygen species metabolic process	10	3.87e-01	1.58e-01	6.71e-01
GO:0071480 cellular response to gamma radiation	14	3.07e-01	-1.58e-01	6.00e-01
GO:0005010 insulin-like growth factor receptor activity	14	3.07e-01	-1.58e-01	6.00e-01
GO:0030155 regulation of cell adhesion	18	2.49e-01	-1.57e-01	5.40e-01
GO:0000956 nuclear-transcribed mRNA catabolic process	12	3.47e-01	-1.57e-01	6.48e-01
GO:0032206 positive regulation of telomere maintenance	14	3.10e-01	-1.57e-01	6.02e-01
GO:0035791 platelet-derived growth factor receptor-beta signaling pathway	16	2.79e-01	-1.56e-01	5.69e-01
GO:0005739 mitochondrion	607	6.97e-11	1.56e-01	1.76e-08
GO:0060324 face development	14	3.12e-01	-1.56e-01	6.06e-01
GO:0035567 non-canonical Wnt signaling pathway	13	3.30e-01	-1.56e-01	6.30e-01
GO:0045214 sarcomere organization	12	3.50e-01	1.56e-01	6.50e-01
GO:0043596 nuclear replication fork	10	3.94e-01	1.56e-01	6.76e-01
GO:0022626 cytosolic ribosome	13	3.32e-01	-1.56e-01	6.31e-01
GO:0046627 negative regulation of insulin receptor signaling pathway	16	2.84e-01	1.55e-01	5.75e-01
GO:0007179 transforming growth factor beta receptor signaling pathway	48	6.45e-02	-1.54e-01	2.65e-01
GO:0006816 calcium ion transport	19	2.44e-01	1.54e-01	5.36e-01
GO:0012507 ER to Golgi transport vesicle membrane	11	3.76e-01	1.54e-01	6.70e-01
GO:0001658 branching involved in ureteric bud morphogenesis	16	2.85e-01	-1.54e-01	5.75e-01
GO:0017053 transcription repressor complex	34	1.20e-01	-1.54e-01	3.76e-01
GO:0004713 protein tyrosine kinase activity	34	1.20e-01	-1.54e-01	3.76e-01
GO:0060271 cilium assembly	124	3.11e-03	1.54e-01	4.32e-02
GO:0005871 kinesin complex	22	2.14e-01	-1.53e-01	5.10e-01
GO:0044331 cell-cell adhesion mediated by cadherin	11	3.80e-01	1.53e-01	6.71e-01
GO:0001540 amyloid-beta binding	28	1.62e-01	1.53e-01	4.35e-01
GO:0019843 rRNA binding	22	2.15e-01	1.53e-01	5.11e-01
GO:0004677 DNA-dependent protein kinase activity	31	1.41e-01	-1.53e-01	4.11e-01
GO:0030897 HOPS complex	10	4.04e-01	-1.53e-01	6.85e-01
GO:0005765 lysosomal membrane	137	2.13e-03	1.52e-01	3.42e-02
GO:0035264 multicellular organism growth	66	3.29e-02	-1.52e-01	1.82e-01
GO:0001843 neural tube closure	48	6.87e-02	-1.52e-01	2.68e-01
GO:0005044 scavenger receptor activity	10	4.06e-01	1.52e-01	6.86e-01
GO:0003887 DNA-directed DNA polymerase activity	16	2.93e-01	-1.52e-01	5.83e-01
GO:0009925 basal plasma membrane	12	3.63e-01	1.52e-01	6.61e-01
GO:0005685 U1 snRNP	12	3.64e-01	1.51e-01	6.61e-01
GO:0016192 vesicle-mediated transport	101	8.65e-03	1.51e-01	8.43e-02
GO:0034113 heterotypic cell-cell adhesion	12	3.64e-01	-1.51e-01	6.61e-01
GO:0045944 positive regulation of transcription by RNA polymerase II	527	3.68e-09	-1.51e-01	4.33e-07
GO:0009615 response to virus	29	1.60e-01	1.51e-01	4.34e-01
GO:0061136 regulation of proteasomal protein catabolic process	11	3.87e-01	1.51e-01	6.71e-01
GO:0035402 histone H3T11 kinase activity	30	1.54e-01	-1.50e-01	4.25e-01
GO:0044022 histone H3S28 kinase activity	30	1.54e-01	-1.50e-01	4.25e-01
GO:0044023 histone H4S1 kinase activity	30	1.54e-01	-1.50e-01	4.25e-01
GO:0044024 histone H2AS1 kinase activity	30	1.54e-01	-1.50e-01	4.25e-01
GO:0044025 histone H2BS14 kinase activity	30	1.54e-01	-1.50e-01	4.25e-01
GO:0072371 histone H2AS121 kinase activity	30	1.54e-01	-1.50e-01	4.25e-01
GO:0140855 histone H3S57 kinase activity	30	1.54e-01	-1.50e-01	4.25e-01
GO:0140857 histone H3T45 kinase activity	30	1.54e-01	-1.50e-01	4.25e-01
GO:0072518 Rho-dependent protein serine/threonine kinase activity	32	1.41e-01	-1.50e-01	4.11e-01
GO:0005109 frizzled binding	19	2.58e-01	-1.50e-01	5.47e-01
GO:0070373 negative regulation of ERK1 and ERK2 cascade	30	1.56e-01	-1.50e-01	4.28e-01
GO:0070063 RNA polymerase binding	12	3.70e-01	1.50e-01	6.66e-01
GO:0034220 monoatomic ion transmembrane transport	20	2.47e-01	1.49e-01	5.39e-01
GO:0120162 positive regulation of cold-induced thermogenesis	31	1.50e-01	1.49e-01	4.25e-01
GO:0005905 clathrin-coated pit	30	1.57e-01	1.49e-01	4.30e-01
GO:0090443 FAR/SIN/STRIPAK complex	12	3.71e-01	1.49e-01	6.67e-01
GO:0010839 negative regulation of keratinocyte proliferation	14	3.34e-01	1.49e-01	6.33e-01
GO:0008092 cytoskeletal protein binding	15	3.17e-01	-1.49e-01	6.11e-01
GO:0046907 intracellular transport	14	3.34e-01	1.49e-01	6.33e-01
GO:0015631 tubulin binding	27	1.80e-01	1.49e-01	4.61e-01
GO:0050918 positive chemotaxis	13	3.52e-01	1.49e-01	6.52e-01
GO:0045184 establishment of protein localization	17	2.88e-01	1.49e-01	5.78e-01
GO:0008217 regulation of blood pressure	20	2.49e-01	-1.49e-01	5.41e-01
GO:0045880 positive regulation of smoothened signaling pathway	22	2.28e-01	-1.49e-01	5.23e-01
GO:0003677 DNA binding	335	3.40e-06	-1.48e-01	2.30e-04
GO:0045893 positive regulation of DNA-templated transcription	224	1.38e-04	-1.48e-01	4.68e-03
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific	183	5.62e-04	-1.48e-01	1.34e-02
GO:0001666 response to hypoxia	51	6.77e-02	-1.48e-01	2.67e-01
GO:0052689 carboxylic ester hydrolase activity	12	3.75e-01	1.48e-01	6.70e-01
GO:0005795 Golgi stack	18	2.78e-01	1.48e-01	5.69e-01
GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction	21	2.41e-01	-1.48e-01	5.34e-01
GO:0016604 nuclear body	173	8.30e-04	-1.48e-01	1.78e-02
GO:0051015 actin filament binding	120	5.33e-03	-1.47e-01	6.49e-02
GO:0019905 syntaxin binding	25	2.02e-01	1.47e-01	4.90e-01
GO:0030332 cyclin binding	20	2.55e-01	-1.47e-01	5.46e-01
GO:0000775 chromosome, centromeric region	31	1.56e-01	1.47e-01	4.29e-01
GO:0004497 monooxygenase activity	11	3.99e-01	-1.47e-01	6.80e-01
GO:0004842 ubiquitin-protein transferase activity	65	4.08e-02	-1.47e-01	2.04e-01
GO:0005789 endoplasmic reticulum membrane	404	4.89e-07	1.47e-01	4.11e-05
GO:0030490 maturation of SSU-rRNA	12	3.80e-01	1.46e-01	6.71e-01
GO:0051028 mRNA transport	27	1.88e-01	-1.46e-01	4.72e-01
GO:0050680 negative regulation of epithelial cell proliferation	24	2.15e-01	-1.46e-01	5.11e-01
GO:0035175 histone H3S10 kinase activity	31	1.59e-01	-1.46e-01	4.31e-01
GO:0072354 histone H3T3 kinase activity	31	1.59e-01	-1.46e-01	4.31e-01
GO:0050853 B cell receptor signaling pathway	19	2.70e-01	-1.46e-01	5.60e-01
GO:0045727 positive regulation of translation	36	1.30e-01	1.46e-01	3.89e-01
GO:0030216 keratinocyte differentiation	28	1.81e-01	-1.46e-01	4.62e-01
GO:0097150 neuronal stem cell population maintenance	18	2.84e-01	-1.46e-01	5.75e-01
GO:0005262 calcium channel activity	21	2.48e-01	1.46e-01	5.39e-01
GO:0030215 semaphorin receptor binding	13	3.63e-01	-1.46e-01	6.61e-01
GO:0006879 intracellular iron ion homeostasis	31	1.61e-01	1.46e-01	4.34e-01
GO:0005164 tumor necrosis factor receptor binding	13	3.63e-01	-1.46e-01	6.61e-01
GO:0014009 glial cell proliferation	10	4.25e-01	-1.46e-01	6.99e-01
GO:1902018 negative regulation of cilium assembly	13	3.64e-01	-1.46e-01	6.61e-01
GO:0038062 protein tyrosine kinase collagen receptor activity	14	3.46e-01	-1.45e-01	6.48e-01
GO:0086091 regulation of heart rate by cardiac conduction	18	2.85e-01	-1.45e-01	5.75e-01
GO:0001657 ureteric bud development	13	3.67e-01	-1.45e-01	6.62e-01
GO:0032266 phosphatidylinositol-3-phosphate binding	32	1.57e-01	1.45e-01	4.30e-01
GO:0005008 hepatocyte growth factor receptor activity	14	3.49e-01	-1.44e-01	6.50e-01
GO:0000124 SAGA complex	15	3.33e-01	-1.44e-01	6.33e-01
GO:0008286 insulin receptor signaling pathway	49	8.07e-02	-1.44e-01	2.94e-01
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process	19	2.77e-01	1.44e-01	5.69e-01
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway	19	2.77e-01	-1.44e-01	5.69e-01
GO:0044291 cell-cell contact zone	14	3.51e-01	-1.44e-01	6.51e-01
GO:0007026 negative regulation of microtubule depolymerization	17	3.05e-01	-1.44e-01	5.99e-01
GO:0070371 ERK1 and ERK2 cascade	20	2.66e-01	1.44e-01	5.58e-01
GO:0005801 cis-Golgi network	28	1.89e-01	1.43e-01	4.73e-01
GO:0007368 determination of left/right symmetry	28	1.89e-01	1.43e-01	4.73e-01
GO:0051233 spindle midzone	17	3.07e-01	1.43e-01	6.00e-01
GO:0006275 regulation of DNA replication	24	2.25e-01	-1.43e-01	5.22e-01
GO:0090575 RNA polymerase II transcription regulator complex	53	7.20e-02	-1.43e-01	2.75e-01
GO:0022008 neurogenesis	31	1.69e-01	-1.43e-01	4.42e-01
GO:0090734 site of DNA damage	22	2.46e-01	-1.43e-01	5.38e-01
GO:0030177 positive regulation of Wnt signaling pathway	17	3.10e-01	-1.42e-01	6.02e-01
GO:0016887 ATP hydrolysis activity	216	3.27e-04	-1.42e-01	8.62e-03
GO:0003924 GTPase activity	175	1.21e-03	1.42e-01	2.22e-02
GO:0030515 snoRNA binding	14	3.57e-01	-1.42e-01	6.59e-01
GO:0005802 trans-Golgi network	101	1.37e-02	1.42e-01	1.10e-01
GO:0070300 phosphatidic acid binding	13	3.75e-01	-1.42e-01	6.70e-01
GO:0048511 rhythmic process	25	2.20e-01	-1.42e-01	5.16e-01
GO:0071346 cellular response to type II interferon	24	2.30e-01	1.42e-01	5.23e-01
GO:0005759 mitochondrial matrix	119	7.75e-03	1.42e-01	7.91e-02
GO:0032743 positive regulation of interleukin-2 production	16	3.28e-01	1.41e-01	6.26e-01
GO:0051289 protein homotetramerization	35	1.50e-01	1.41e-01	4.25e-01
GO:0005778 peroxisomal membrane	28	1.99e-01	1.40e-01	4.87e-01
GO:0031072 heat shock protein binding	27	2.08e-01	-1.40e-01	5.00e-01
GO:0003730 mRNA 3’-UTR binding	51	8.36e-02	-1.40e-01	2.99e-01
GO:0045335 phagocytic vesicle	36	1.46e-01	1.40e-01	4.22e-01
GO:0001569 branching involved in blood vessel morphogenesis	15	3.48e-01	-1.40e-01	6.50e-01
GO:0016342 catenin complex	13	3.83e-01	-1.40e-01	6.71e-01
GO:0045740 positive regulation of DNA replication	11	4.22e-01	-1.40e-01	6.98e-01
GO:0030324 lung development	35	1.53e-01	-1.40e-01	4.25e-01
GO:0005019 platelet-derived growth factor beta-receptor activity	14	3.66e-01	-1.40e-01	6.62e-01
GO:0007259 cell surface receptor signaling pathway via JAK-STAT	21	2.69e-01	1.39e-01	5.59e-01
GO:0007064 mitotic sister chromatid cohesion	10	4.46e-01	1.39e-01	7.11e-01
GO:0030225 macrophage differentiation	11	4.24e-01	1.39e-01	6.99e-01
GO:0140823 histone H2BS36 kinase activity	31	1.80e-01	-1.39e-01	4.61e-01
GO:0050681 nuclear androgen receptor binding	16	3.36e-01	-1.39e-01	6.33e-01
GO:0045732 positive regulation of protein catabolic process	46	1.03e-01	1.39e-01	3.40e-01
GO:0005005 transmembrane-ephrin receptor activity	15	3.53e-01	-1.39e-01	6.52e-01
GO:2000648 positive regulation of stem cell proliferation	12	4.06e-01	1.39e-01	6.86e-01
GO:0032467 positive regulation of cytokinesis	14	3.70e-01	-1.38e-01	6.66e-01
GO:0060326 cell chemotaxis	28	2.05e-01	-1.38e-01	4.96e-01
GO:0016787 hydrolase activity	108	1.33e-02	-1.38e-01	1.08e-01
GO:0017018 myosin phosphatase activity	13	3.89e-01	-1.38e-01	6.71e-01
GO:0140791 histone H2AXS140 phosphatase activity	13	3.89e-01	-1.38e-01	6.71e-01
GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	13	3.89e-01	-1.38e-01	6.71e-01
GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	13	3.89e-01	-1.38e-01	6.71e-01
GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	13	3.89e-01	-1.38e-01	6.71e-01
GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	13	3.89e-01	-1.38e-01	6.71e-01
GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	13	3.89e-01	-1.38e-01	6.71e-01
GO:1990439 MAP kinase serine/threonine phosphatase activity	13	3.89e-01	-1.38e-01	6.71e-01
GO:0097431 mitotic spindle pole	27	2.16e-01	-1.38e-01	5.11e-01
GO:0140359 ABC-type transporter activity	12	4.11e-01	-1.37e-01	6.91e-01
GO:0016605 PML body	61	6.50e-02	-1.37e-01	2.66e-01
GO:0045211 postsynaptic membrane	57	7.51e-02	-1.36e-01	2.82e-01
GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	35	1.63e-01	-1.36e-01	4.38e-01
GO:0072583 clathrin-dependent endocytosis	19	3.05e-01	1.36e-01	5.99e-01
GO:0070098 chemokine-mediated signaling pathway	10	4.59e-01	-1.35e-01	7.22e-01
GO:0006352 DNA-templated transcription initiation	11	4.39e-01	-1.35e-01	7.08e-01
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator	11	4.39e-01	-1.35e-01	7.08e-01
GO:0008344 adult locomotory behavior	23	2.69e-01	-1.33e-01	5.59e-01
GO:0140801 histone H2AXY142 kinase activity	23	2.69e-01	-1.33e-01	5.59e-01
GO:0051082 unfolded protein binding	56	8.52e-02	1.33e-01	3.02e-01
GO:0005694 chromosome	76	4.51e-02	-1.33e-01	2.16e-01
GO:0001822 kidney development	52	9.73e-02	-1.33e-01	3.28e-01
GO:0007129 homologous chromosome pairing at meiosis	13	4.07e-01	-1.33e-01	6.86e-01
GO:0042327 positive regulation of phosphorylation	12	4.26e-01	1.33e-01	6.99e-01
GO:0003727 single-stranded RNA binding	21	2.94e-01	-1.32e-01	5.84e-01
GO:0032456 endocytic recycling	42	1.38e-01	1.32e-01	4.06e-01
GO:0001650 fibrillar center	102	2.13e-02	-1.32e-01	1.44e-01
GO:0034644 cellular response to UV	33	1.90e-01	-1.32e-01	4.73e-01
GO:0009968 negative regulation of signal transduction	14	3.93e-01	1.32e-01	6.76e-01
GO:0005977 glycogen metabolic process	14	3.93e-01	1.32e-01	6.76e-01
GO:0000165 MAPK cascade	46	1.23e-01	-1.31e-01	3.80e-01
GO:0012505 endomembrane system	97	2.56e-02	1.31e-01	1.60e-01
GO:0010824 regulation of centrosome duplication	15	3.79e-01	1.31e-01	6.71e-01
GO:0071549 cellular response to dexamethasone stimulus	11	4.54e-01	1.30e-01	7.20e-01
GO:0006509 membrane protein ectodomain proteolysis	15	3.83e-01	-1.30e-01	6.71e-01
GO:0071364 cellular response to epidermal growth factor stimulus	19	3.27e-01	1.30e-01	6.26e-01
GO:0071805 potassium ion transmembrane transport	39	1.61e-01	1.30e-01	4.35e-01
GO:0007264 small GTPase-mediated signal transduction	47	1.25e-01	-1.29e-01	3.83e-01
GO:0051726 regulation of cell cycle	104	2.29e-02	-1.29e-01	1.49e-01
GO:0048010 vascular endothelial growth factor receptor signaling pathway	13	4.20e-01	-1.29e-01	6.98e-01
GO:0051018 protein kinase A binding	12	4.39e-01	-1.29e-01	7.08e-01
GO:0030864 cortical actin cytoskeleton	32	2.08e-01	-1.29e-01	5.00e-01
GO:0051881 regulation of mitochondrial membrane potential	15	3.89e-01	1.29e-01	6.71e-01
GO:0072344 rescue of stalled ribosome	26	2.57e-01	1.28e-01	5.47e-01
GO:0009887 animal organ morphogenesis	34	1.98e-01	-1.28e-01	4.85e-01
GO:0032728 positive regulation of interferon-beta production	15	3.93e-01	-1.28e-01	6.76e-01
GO:0090307 mitotic spindle assembly	30	2.27e-01	-1.27e-01	5.23e-01
GO:0006629 lipid metabolic process	52	1.12e-01	1.27e-01	3.61e-01
GO:0044297 cell body	24	2.81e-01	1.27e-01	5.72e-01
GO:0044389 ubiquitin-like protein ligase binding	16	3.78e-01	1.27e-01	6.71e-01
GO:0001669 acrosomal vesicle	26	2.63e-01	1.27e-01	5.54e-01
GO:0140297 DNA-binding transcription factor binding	72	6.31e-02	-1.27e-01	2.62e-01
GO:0048167 regulation of synaptic plasticity	15	3.96e-01	-1.27e-01	6.78e-01
GO:0032012 regulation of ARF protein signal transduction	14	4.12e-01	-1.27e-01	6.92e-01
GO:0005637 nuclear inner membrane	24	2.84e-01	1.26e-01	5.75e-01
GO:0007097 nuclear migration	15	3.97e-01	-1.26e-01	6.79e-01
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding	85	4.43e-02	-1.26e-01	2.14e-01
GO:0007005 mitochondrion organization	62	8.57e-02	1.26e-01	3.03e-01
GO:0055037 recycling endosome	56	1.03e-01	1.26e-01	3.40e-01
GO:0035249 synaptic transmission, glutamatergic	16	3.83e-01	-1.26e-01	6.71e-01
GO:0015031 protein transport	173	4.49e-03	1.25e-01	5.70e-02
GO:0016301 kinase activity	13	4.34e-01	1.25e-01	7.08e-01
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle	23	2.99e-01	-1.25e-01	5.92e-01
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT	14	4.18e-01	-1.25e-01	6.97e-01
GO:0046580 negative regulation of Ras protein signal transduction	13	4.35e-01	1.25e-01	7.08e-01
GO:0004676 3-phosphoinositide-dependent protein kinase activity	31	2.29e-01	-1.25e-01	5.23e-01
GO:0048821 erythrocyte development	14	4.19e-01	-1.25e-01	6.97e-01
GO:0031124 mRNA 3’-end processing	13	4.36e-01	-1.25e-01	7.08e-01
GO:0005911 cell-cell junction	77	5.87e-02	-1.25e-01	2.49e-01
GO:0006281 DNA repair	95	3.59e-02	-1.25e-01	1.88e-01
GO:0048146 positive regulation of fibroblast proliferation	19	3.47e-01	-1.25e-01	6.48e-01
GO:0004679 AMP-activated protein kinase activity	32	2.23e-01	-1.24e-01	5.20e-01
GO:0035403 histone H3T6 kinase activity	32	2.24e-01	-1.24e-01	5.20e-01
GO:0006368 transcription elongation by RNA polymerase II	24	2.92e-01	-1.24e-01	5.82e-01
GO:0043122 regulation of canonical NF-kappaB signal transduction	18	3.65e-01	1.23e-01	6.61e-01
GO:0010608 post-transcriptional regulation of gene expression	11	4.80e-01	1.23e-01	7.41e-01
GO:0099170 postsynaptic modulation of chemical synaptic transmission	13	4.43e-01	-1.23e-01	7.08e-01
GO:1904047 S-adenosyl-L-methionine binding	13	4.44e-01	1.23e-01	7.08e-01
GO:0030336 negative regulation of cell migration	51	1.30e-01	-1.23e-01	3.90e-01
GO:0070847 core mediator complex	19	3.56e-01	1.22e-01	6.57e-01
GO:0045814 negative regulation of gene expression, epigenetic	16	3.97e-01	-1.22e-01	6.79e-01
GO:0005525 GTP binding	211	2.24e-03	1.22e-01	3.56e-02
GO:0004622 lysophospholipase activity	10	5.03e-01	1.22e-01	7.60e-01
GO:0005682 U5 snRNP	10	5.03e-01	-1.22e-01	7.60e-01
GO:0072542 protein phosphatase activator activity	10	5.06e-01	-1.21e-01	7.61e-01
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	11	4.86e-01	1.21e-01	7.47e-01
GO:0006882 intracellular zinc ion homeostasis	13	4.49e-01	1.21e-01	7.14e-01
GO:0032580 Golgi cisterna membrane	26	2.85e-01	1.21e-01	5.75e-01
GO:0007224 smoothened signaling pathway	49	1.43e-01	1.21e-01	4.15e-01
GO:0005198 structural molecule activity	38	1.99e-01	1.21e-01	4.86e-01
GO:2000300 regulation of synaptic vesicle exocytosis	19	3.63e-01	1.20e-01	6.61e-01
GO:0050728 negative regulation of inflammatory response	49	1.45e-01	1.20e-01	4.20e-01
GO:0071577 zinc ion transmembrane transport	10	5.11e-01	-1.20e-01	7.65e-01
GO:0001578 microtubule bundle formation	15	4.22e-01	-1.20e-01	6.98e-01
GO:0016922 nuclear receptor binding	21	3.43e-01	-1.20e-01	6.45e-01
GO:0097194 execution phase of apoptosis	10	5.13e-01	1.19e-01	7.65e-01
GO:0007281 germ cell development	14	4.39e-01	-1.19e-01	7.08e-01
GO:0031145 anaphase-promoting complex-dependent catabolic process	14	4.40e-01	-1.19e-01	7.08e-01
GO:0098552 side of membrane	15	4.26e-01	1.19e-01	6.99e-01
GO:0006298 mismatch repair	16	4.12e-01	1.18e-01	6.92e-01
GO:0010468 regulation of gene expression	59	1.16e-01	-1.18e-01	3.70e-01
GO:0038084 vascular endothelial growth factor signaling pathway	24	3.17e-01	-1.18e-01	6.11e-01
GO:0043138 3’-5’ DNA helicase activity	10	5.18e-01	-1.18e-01	7.66e-01
GO:0002230 positive regulation of defense response to virus by host	11	4.99e-01	-1.18e-01	7.57e-01
GO:0051787 misfolded protein binding	12	4.80e-01	1.18e-01	7.41e-01
GO:0031902 late endosome membrane	66	9.81e-02	1.18e-01	3.29e-01
GO:0034497 protein localization to phagophore assembly site	11	5.01e-01	1.17e-01	7.59e-01
GO:0019838 growth factor binding	11	5.01e-01	-1.17e-01	7.59e-01
GO:0032039 integrator complex	15	4.32e-01	-1.17e-01	7.07e-01
GO:1902600 proton transmembrane transport	59	1.21e-01	1.17e-01	3.76e-01
GO:0043495 protein-membrane adaptor activity	17	4.04e-01	1.17e-01	6.85e-01
GO:0060586 multicellular organismal-level iron ion homeostasis	15	4.34e-01	-1.17e-01	7.08e-01
GO:0030041 actin filament polymerization	15	4.35e-01	1.17e-01	7.08e-01
GO:0045022 early endosome to late endosome transport	19	3.80e-01	1.16e-01	6.71e-01
GO:0005516 calmodulin binding	68	9.78e-02	-1.16e-01	3.29e-01
GO:0000281 mitotic cytokinesis	34	2.42e-01	-1.16e-01	5.34e-01
GO:0032755 positive regulation of interleukin-6 production	32	2.57e-01	1.16e-01	5.47e-01
GO:0035401 histone H3Y41 kinase activity	22	3.47e-01	-1.16e-01	6.49e-01
GO:0008283 cell population proliferation	65	1.07e-01	-1.16e-01	3.49e-01
GO:0005125 cytokine activity	28	2.90e-01	-1.16e-01	5.81e-01
GO:0001938 positive regulation of endothelial cell proliferation	23	3.38e-01	1.15e-01	6.37e-01
GO:0005903 brush border	19	3.84e-01	-1.15e-01	6.71e-01
GO:0030837 negative regulation of actin filament polymerization	14	4.55e-01	1.15e-01	7.21e-01
GO:0032735 positive regulation of interleukin-12 production	12	4.90e-01	1.15e-01	7.49e-01
GO:0008306 associative learning	11	5.09e-01	-1.15e-01	7.64e-01
GO:0048705 skeletal system morphogenesis	15	4.43e-01	1.14e-01	7.08e-01
GO:0033077 T cell differentiation in thymus	18	4.02e-01	-1.14e-01	6.82e-01
GO:0002250 adaptive immune response	19	3.90e-01	1.14e-01	6.73e-01
GO:0007219 Notch signaling pathway	40	2.16e-01	-1.13e-01	5.11e-01
GO:0005515 protein binding	91	6.25e-02	-1.13e-01	2.60e-01
GO:0005769 early endosome	141	2.09e-02	1.13e-01	1.43e-01
GO:0001818 negative regulation of cytokine production	11	5.18e-01	1.13e-01	7.66e-01
GO:0030672 synaptic vesicle membrane	44	1.97e-01	1.12e-01	4.85e-01
GO:0048786 presynaptic active zone	10	5.40e-01	-1.12e-01	7.74e-01
GO:0048144 fibroblast proliferation	22	3.64e-01	1.12e-01	6.61e-01
GO:0008654 phospholipid biosynthetic process	12	5.06e-01	1.11e-01	7.61e-01
GO:0033192 calmodulin-dependent protein phosphatase activity	16	4.42e-01	-1.11e-01	7.08e-01
GO:0005249 voltage-gated potassium channel activity	14	4.73e-01	-1.11e-01	7.37e-01
GO:0051020 GTPase binding	15	4.57e-01	-1.11e-01	7.22e-01
GO:0007018 microtubule-based movement	40	2.25e-01	-1.11e-01	5.22e-01
GO:0007266 Rho protein signal transduction	33	2.71e-01	-1.11e-01	5.61e-01
GO:0034237 protein kinase A regulatory subunit binding	15	4.58e-01	-1.11e-01	7.22e-01
GO:0050870 positive regulation of T cell activation	13	4.90e-01	1.11e-01	7.49e-01
GO:0030154 cell differentiation	140	2.43e-02	-1.10e-01	1.53e-01
GO:0030010 establishment of cell polarity	19	4.05e-01	-1.10e-01	6.86e-01
GO:0006884 cell volume homeostasis	14	4.77e-01	-1.10e-01	7.39e-01
GO:0051016 barbed-end actin filament capping	16	4.49e-01	-1.09e-01	7.14e-01
GO:0030500 regulation of bone mineralization	12	5.12e-01	1.09e-01	7.65e-01
GO:0071347 cellular response to interleukin-1	17	4.36e-01	1.09e-01	7.08e-01
GO:0072089 stem cell proliferation	21	3.87e-01	-1.09e-01	6.71e-01
GO:0005975 carbohydrate metabolic process	49	1.90e-01	1.08e-01	4.73e-01
GO:0004519 endonuclease activity	13	5.01e-01	-1.08e-01	7.59e-01
GO:0031547 brain-derived neurotrophic factor receptor signaling pathway	15	4.70e-01	-1.08e-01	7.36e-01
GO:0016601 Rac protein signal transduction	17	4.43e-01	-1.08e-01	7.08e-01
GO:0030178 negative regulation of Wnt signaling pathway	17	4.43e-01	-1.07e-01	7.08e-01
GO:0001673 male germ cell nucleus	27	3.35e-01	-1.07e-01	6.33e-01
GO:0051457 maintenance of protein location in nucleus	10	5.57e-01	-1.07e-01	7.85e-01
GO:0060021 roof of mouth development	36	2.66e-01	-1.07e-01	5.58e-01
GO:0070006 metalloaminopeptidase activity	15	4.73e-01	1.07e-01	7.37e-01
GO:0070536 protein K63-linked deubiquitination	16	4.59e-01	-1.07e-01	7.22e-01
GO:0120009 intermembrane lipid transfer	16	4.63e-01	1.06e-01	7.26e-01
GO:0051216 cartilage development	21	4.01e-01	-1.06e-01	6.82e-01
GO:0034067 protein localization to Golgi apparatus	13	5.09e-01	1.06e-01	7.64e-01
GO:0062023 collagen-containing extracellular matrix	72	1.21e-01	-1.06e-01	3.76e-01
GO:0017134 fibroblast growth factor binding	12	5.27e-01	1.06e-01	7.74e-01
GO:0030246 carbohydrate binding	39	2.54e-01	-1.06e-01	5.46e-01
GO:0008203 cholesterol metabolic process	31	3.09e-01	-1.06e-01	6.02e-01
GO:0071011 precatalytic spliceosome	12	5.27e-01	1.05e-01	7.74e-01
GO:0000049 tRNA binding	52	1.89e-01	1.05e-01	4.73e-01
GO:0001937 negative regulation of endothelial cell proliferation	12	5.29e-01	-1.05e-01	7.74e-01
GO:0006366 transcription by RNA polymerase II	73	1.21e-01	-1.05e-01	3.76e-01
GO:0004177 aminopeptidase activity	13	5.14e-01	-1.05e-01	7.65e-01
GO:1904019 epithelial cell apoptotic process	13	5.14e-01	1.05e-01	7.65e-01
GO:2000811 negative regulation of anoikis	10	5.67e-01	1.04e-01	7.94e-01
GO:0034599 cellular response to oxidative stress	44	2.31e-01	1.04e-01	5.23e-01
GO:0070530 K63-linked polyubiquitin modification-dependent protein binding	17	4.57e-01	-1.04e-01	7.22e-01
GO:0007040 lysosome organization	33	3.01e-01	-1.04e-01	5.95e-01
GO:0008361 regulation of cell size	13	5.16e-01	-1.04e-01	7.66e-01
GO:0001965 G-protein alpha-subunit binding	10	5.69e-01	1.04e-01	7.95e-01
GO:0007204 positive regulation of cytosolic calcium ion concentration	20	4.21e-01	-1.04e-01	6.98e-01
GO:0060038 cardiac muscle cell proliferation	12	5.33e-01	-1.04e-01	7.74e-01
GO:0006612 protein targeting to membrane	24	3.80e-01	1.03e-01	6.71e-01
GO:0005657 replication fork	20	4.23e-01	1.03e-01	6.99e-01
GO:0003785 actin monomer binding	14	5.04e-01	-1.03e-01	7.61e-01
GO:0072657 protein localization to membrane	19	4.39e-01	-1.03e-01	7.08e-01
GO:0004198 calcium-dependent cysteine-type endopeptidase activity	10	5.78e-01	1.02e-01	8.00e-01
GO:0032993 protein-DNA complex	21	4.21e-01	-1.01e-01	6.98e-01
GO:0032526 response to retinoic acid	15	4.97e-01	-1.01e-01	7.55e-01
GO:0005884 actin filament	43	2.52e-01	-1.01e-01	5.43e-01
GO:0006644 phospholipid metabolic process	11	5.63e-01	-1.01e-01	7.92e-01
GO:0007405 neuroblast proliferation	21	4.25e-01	-1.01e-01	6.99e-01
GO:0008104 protein localization	68	1.52e-01	-1.01e-01	4.25e-01
GO:0043679 axon terminus	17	4.73e-01	-1.00e-01	7.37e-01
GO:0071944 cell periphery	12	5.49e-01	9.99e-02	7.80e-01
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway	28	3.62e-01	9.96e-02	6.61e-01
GO:0043113 receptor clustering	13	5.35e-01	9.95e-02	7.74e-01
GO:0045600 positive regulation of fat cell differentiation	21	4.30e-01	-9.94e-02	7.05e-01
GO:0016323 basolateral plasma membrane	95	9.50e-02	-9.92e-02	3.22e-01
GO:0008143 poly(A) binding	13	5.36e-01	-9.91e-02	7.74e-01
GO:0006898 receptor-mediated endocytosis	24	4.01e-01	-9.91e-02	6.82e-01
GO:0006887 exocytosis	44	2.56e-01	9.91e-02	5.47e-01
GO:0001784 phosphotyrosine residue binding	27	3.73e-01	-9.90e-02	6.70e-01
GO:0030552 cAMP binding	10	5.88e-01	9.89e-02	8.04e-01
GO:0006513 protein monoubiquitination	27	3.75e-01	9.87e-02	6.70e-01
GO:0048787 presynaptic active zone membrane	11	5.71e-01	9.86e-02	7.96e-01
GO:0005004 GPI-linked ephrin receptor activity	13	5.39e-01	-9.84e-02	7.74e-01
GO:0005011 macrophage colony-stimulating factor receptor activity	13	5.39e-01	-9.84e-02	7.74e-01
GO:0005018 platelet-derived growth factor alpha-receptor activity	13	5.39e-01	-9.84e-02	7.74e-01
GO:0005020 stem cell factor receptor activity	13	5.39e-01	-9.84e-02	7.74e-01
GO:0008288 boss receptor activity	13	5.39e-01	-9.84e-02	7.74e-01
GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway	13	5.39e-01	-9.84e-02	7.74e-01
GO:0036323 vascular endothelial growth factor receptor-1 signaling pathway	13	5.39e-01	-9.84e-02	7.74e-01
GO:0036332 placental growth factor receptor activity	13	5.39e-01	-9.84e-02	7.74e-01
GO:0038145 macrophage colony-stimulating factor signaling pathway	13	5.39e-01	-9.84e-02	7.74e-01
GO:0060175 brain-derived neurotrophic factor receptor activity	13	5.39e-01	-9.84e-02	7.74e-01
GO:0005788 endoplasmic reticulum lumen	40	2.82e-01	-9.84e-02	5.74e-01
GO:0071260 cellular response to mechanical stimulus	23	4.15e-01	9.82e-02	6.94e-01
GO:0010467 gene expression	81	1.27e-01	-9.81e-02	3.87e-01
GO:0048701 embryonic cranial skeleton morphogenesis	13	5.41e-01	9.80e-02	7.74e-01
GO:0031966 mitochondrial membrane	38	2.96e-01	9.79e-02	5.88e-01
GO:0090263 positive regulation of canonical Wnt signaling pathway	61	1.86e-01	-9.79e-02	4.69e-01
GO:0010976 positive regulation of neuron projection development	29	3.63e-01	-9.77e-02	6.61e-01
GO:0044183 protein folding chaperone	21	4.39e-01	9.75e-02	7.08e-01
GO:0000974 Prp19 complex	10	5.96e-01	-9.68e-02	8.07e-01
GO:0004711 ribosomal protein S6 kinase activity	32	3.46e-01	-9.63e-02	6.48e-01
GO:0050727 regulation of inflammatory response	26	3.96e-01	9.62e-02	6.78e-01
GO:0005686 U2 snRNP	16	5.06e-01	-9.61e-02	7.61e-01
GO:0048255 mRNA stabilization	16	5.06e-01	-9.61e-02	7.61e-01
GO:0090303 positive regulation of wound healing	11	5.81e-01	9.61e-02	8.01e-01
GO:0030282 bone mineralization	23	4.26e-01	-9.60e-02	6.99e-01
GO:0006506 GPI anchor biosynthetic process	25	4.06e-01	9.60e-02	6.86e-01
GO:0017124 SH3 domain binding	43	2.77e-01	9.59e-02	5.69e-01
GO:0005112 Notch binding	12	5.65e-01	-9.58e-02	7.93e-01
GO:0006302 double-strand break repair	45	2.67e-01	-9.56e-02	5.58e-01
GO:0045785 positive regulation of cell adhesion	15	5.22e-01	-9.54e-02	7.70e-01
GO:0008270 zinc ion binding	396	1.18e-03	-9.54e-02	2.21e-02
GO:0051059 NF-kappaB binding	22	4.39e-01	9.54e-02	7.08e-01
GO:0030901 midbrain development	11	5.85e-01	-9.51e-02	8.03e-01
GO:0090543 Flemming body	14	5.38e-01	-9.51e-02	7.74e-01
GO:0004674 protein serine/threonine kinase activity	202	2.10e-02	-9.45e-02	1.43e-01
GO:0070830 bicellular tight junction assembly	19	4.77e-01	9.43e-02	7.39e-01
GO:0043005 neuron projection	96	1.11e-01	9.42e-02	3.58e-01
GO:0004252 serine-type endopeptidase activity	50	2.50e-01	9.40e-02	5.42e-01
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	15	5.30e-01	-9.37e-02	7.74e-01
GO:0000145 exocyst	11	5.91e-01	-9.36e-02	8.07e-01
GO:0005819 spindle	55	2.31e-01	-9.35e-02	5.23e-01
GO:0042632 cholesterol homeostasis	39	3.14e-01	9.32e-02	6.08e-01
GO:0008408 3’-5’ exonuclease activity	10	6.11e-01	-9.29e-02	8.16e-01
GO:0051010 microtubule plus-end binding	11	5.94e-01	-9.28e-02	8.07e-01
GO:0097009 energy homeostasis	24	4.34e-01	-9.22e-02	7.08e-01
GO:0010595 positive regulation of endothelial cell migration	26	4.17e-01	-9.20e-02	6.96e-01
GO:0001958 endochondral ossification	15	5.38e-01	9.18e-02	7.74e-01
GO:0051131 chaperone-mediated protein complex assembly	14	5.52e-01	9.17e-02	7.82e-01
GO:0071233 cellular response to L-leucine	10	6.16e-01	-9.15e-02	8.17e-01
GO:0006376 mRNA splice site recognition	12	5.84e-01	-9.13e-02	8.03e-01
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding	12	5.85e-01	-9.10e-02	8.03e-01
GO:0035725 sodium ion transmembrane transport	47	2.82e-01	9.08e-02	5.74e-01
GO:0007274 neuromuscular synaptic transmission	12	5.88e-01	9.03e-02	8.04e-01
GO:0090141 positive regulation of mitochondrial fission	16	5.33e-01	9.01e-02	7.74e-01
GO:0031593 polyubiquitin modification-dependent protein binding	19	4.97e-01	-8.99e-02	7.56e-01
GO:0006511 ubiquitin-dependent protein catabolic process	118	9.26e-02	-8.98e-02	3.18e-01
GO:0003676 nucleic acid binding	106	1.12e-01	-8.95e-02	3.60e-01
GO:0045505 dynein intermediate chain binding	17	5.25e-01	-8.91e-02	7.73e-01
GO:0000502 proteasome complex	13	5.78e-01	8.91e-02	8.00e-01
GO:0051225 spindle assembly	21	4.83e-01	8.84e-02	7.44e-01
GO:0030488 tRNA methylation	20	4.94e-01	8.84e-02	7.52e-01
GO:0051260 protein homooligomerization	48	2.90e-01	-8.83e-02	5.81e-01
GO:0008154 actin polymerization or depolymerization	12	5.96e-01	-8.83e-02	8.07e-01
GO:0017148 negative regulation of translation	43	3.18e-01	-8.80e-02	6.12e-01
GO:0004725 protein tyrosine phosphatase activity	44	3.13e-01	-8.80e-02	6.06e-01
GO:0006805 xenobiotic metabolic process	17	5.31e-01	8.77e-02	7.74e-01
GO:0001223 transcription coactivator binding	22	4.77e-01	-8.76e-02	7.39e-01
GO:0030334 regulation of cell migration	35	3.72e-01	-8.72e-02	6.69e-01
GO:0035115 embryonic forelimb morphogenesis	16	5.48e-01	8.68e-02	7.80e-01
GO:0005978 glycogen biosynthetic process	11	6.19e-01	8.67e-02	8.17e-01
GO:0060349 bone morphogenesis	12	6.03e-01	8.67e-02	8.11e-01
GO:0040014 regulation of multicellular organism growth	12	6.04e-01	-8.65e-02	8.11e-01
GO:0008266 poly(U) RNA binding	16	5.49e-01	8.65e-02	7.80e-01
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway	32	3.98e-01	-8.64e-02	6.79e-01
GO:0008289 lipid binding	44	3.22e-01	8.63e-02	6.18e-01
GO:0045821 positive regulation of glycolytic process	10	6.37e-01	-8.62e-02	8.24e-01
GO:0031167 rRNA methylation	11	6.22e-01	8.59e-02	8.19e-01
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle	27	4.40e-01	-8.59e-02	7.08e-01
GO:0030670 phagocytic vesicle membrane	19	5.18e-01	8.56e-02	7.66e-01
GO:0000151 ubiquitin ligase complex	48	3.06e-01	-8.55e-02	6.00e-01
GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway	16	5.54e-01	-8.54e-02	7.83e-01
GO:0099171 presynaptic modulation of chemical synaptic transmission	11	6.24e-01	8.53e-02	8.20e-01
GO:1990830 cellular response to leukemia inhibitory factor	66	2.31e-01	-8.53e-02	5.23e-01
GO:0032868 response to insulin	22	4.89e-01	-8.52e-02	7.49e-01
GO:0043923 positive regulation by host of viral transcription	12	6.10e-01	-8.51e-02	8.16e-01
GO:0046330 positive regulation of JNK cascade	38	3.64e-01	-8.51e-02	6.61e-01
GO:0042026 protein refolding	12	6.10e-01	-8.50e-02	8.16e-01
GO:0046872 metal ion binding	875	2.56e-05	-8.48e-02	1.22e-03
GO:0016446 somatic hypermutation of immunoglobulin genes	10	6.42e-01	8.48e-02	8.28e-01
GO:0071479 cellular response to ionizing radiation	22	4.92e-01	-8.47e-02	7.50e-01
GO:0003689 DNA clamp loader activity	32	4.08e-01	-8.46e-02	6.87e-01
GO:0008584 male gonad development	28	4.40e-01	-8.43e-02	7.08e-01
GO:0007626 locomotory behavior	26	4.58e-01	8.41e-02	7.22e-01
GO:0005856 cytoskeleton	174	5.68e-02	-8.39e-02	2.44e-01
GO:0005581 collagen trimer	20	5.17e-01	-8.38e-02	7.66e-01
GO:0048704 embryonic skeletal system morphogenesis	18	5.42e-01	8.31e-02	7.75e-01
GO:0046676 negative regulation of insulin secretion	10	6.50e-01	-8.29e-02	8.33e-01
GO:0002244 hematopoietic progenitor cell differentiation	35	4.00e-01	-8.23e-02	6.81e-01
GO:0030097 hemopoiesis	25	4.78e-01	8.21e-02	7.39e-01
GO:0045668 negative regulation of osteoblast differentiation	27	4.61e-01	-8.21e-02	7.24e-01
GO:0043539 protein serine/threonine kinase activator activity	34	4.08e-01	8.20e-02	6.87e-01
GO:0000209 protein polyubiquitination	77	2.16e-01	-8.17e-02	5.11e-01
GO:0001503 ossification	26	4.73e-01	-8.14e-02	7.37e-01
GO:0016567 protein ubiquitination	155	8.17e-02	-8.12e-02	2.96e-01
GO:0031398 positive regulation of protein ubiquitination	40	3.75e-01	8.11e-02	6.70e-01
GO:0050829 defense response to Gram-negative bacterium	12	6.27e-01	8.09e-02	8.22e-01
GO:0021987 cerebral cortex development	24	4.93e-01	8.09e-02	7.51e-01
GO:0031464 Cul4A-RING E3 ubiquitin ligase complex	10	6.59e-01	8.07e-02	8.37e-01
GO:0097550 transcription preinitiation complex	12	6.29e-01	8.06e-02	8.22e-01
GO:0030145 manganese ion binding	45	3.50e-01	-8.05e-02	6.50e-01
GO:0003756 protein disulfide isomerase activity	10	6.59e-01	8.05e-02	8.37e-01
GO:0000070 mitotic sister chromatid segregation	18	5.56e-01	8.01e-02	7.85e-01
GO:0051019 mitogen-activated protein kinase binding	11	6.46e-01	-8.00e-02	8.31e-01
GO:0042472 inner ear morphogenesis	27	4.74e-01	-7.96e-02	7.37e-01
GO:0007094 mitotic spindle assembly checkpoint signaling	19	5.48e-01	7.96e-02	7.80e-01
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway	41	3.78e-01	-7.95e-02	6.71e-01
GO:0051649 establishment of localization in cell	40	3.84e-01	7.95e-02	6.71e-01
GO:0045190 isotype switching	13	6.20e-01	-7.94e-02	8.17e-01
GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction	35	4.16e-01	-7.94e-02	6.95e-01
GO:0050830 defense response to Gram-positive bacterium	15	5.95e-01	7.93e-02	8.07e-01
GO:0043001 Golgi to plasma membrane protein transport	21	5.30e-01	7.92e-02	7.74e-01
GO:0010634 positive regulation of epithelial cell migration	19	5.50e-01	-7.91e-02	7.81e-01
GO:0016055 Wnt signaling pathway	78	2.27e-01	-7.91e-02	5.23e-01
GO:0005923 bicellular tight junction	50	3.35e-01	-7.89e-02	6.33e-01
GO:0000166 nucleotide binding	36	4.13e-01	7.88e-02	6.93e-01
GO:0048666 neuron development	26	4.87e-01	-7.87e-02	7.48e-01
GO:1990498 mitotic spindle microtubule	10	6.67e-01	-7.86e-02	8.39e-01
GO:0006909 phagocytosis	23	5.15e-01	7.85e-02	7.66e-01
GO:0030742 GTP-dependent protein binding	13	6.25e-01	7.83e-02	8.20e-01
GO:0007059 chromosome segregation	41	3.88e-01	7.80e-02	6.71e-01
GO:0071222 cellular response to lipopolysaccharide	45	3.67e-01	-7.78e-02	6.62e-01
GO:0009408 response to heat	19	5.57e-01	-7.78e-02	7.85e-01
GO:0045862 positive regulation of proteolysis	12	6.41e-01	7.77e-02	8.28e-01
GO:0009636 response to toxic substance	15	6.03e-01	-7.75e-02	8.11e-01
GO:0036503 ERAD pathway	59	3.06e-01	7.71e-02	6.00e-01
GO:0030159 signaling receptor complex adaptor activity	13	6.31e-01	-7.69e-02	8.22e-01
GO:0030659 cytoplasmic vesicle membrane	42	3.89e-01	-7.69e-02	6.71e-01
GO:0070840 dynein complex binding	11	6.59e-01	-7.68e-02	8.37e-01
GO:0070273 phosphatidylinositol-4-phosphate binding	17	5.84e-01	-7.68e-02	8.02e-01
GO:0034614 cellular response to reactive oxygen species	16	5.96e-01	7.66e-02	8.07e-01
GO:0034605 cellular response to heat	16	5.99e-01	-7.60e-02	8.09e-01
GO:0060216 definitive hemopoiesis	10	6.77e-01	7.60e-02	8.45e-01
GO:0005794 Golgi apparatus	465	5.34e-03	7.58e-02	6.49e-02
GO:0009306 protein secretion	20	5.57e-01	7.58e-02	7.85e-01
GO:0006397 mRNA processing	72	2.67e-01	-7.58e-02	5.58e-01
GO:0060218 hematopoietic stem cell differentiation	11	6.64e-01	-7.57e-02	8.38e-01
GO:0007166 cell surface receptor signaling pathway	38	4.20e-01	7.56e-02	6.98e-01
GO:0008045 motor neuron axon guidance	12	6.51e-01	-7.55e-02	8.33e-01
GO:0000776 kinetochore	90	2.16e-01	7.55e-02	5.11e-01
GO:0001786 phosphatidylserine binding	25	5.14e-01	7.55e-02	7.65e-01
GO:0035331 negative regulation of hippo signaling	18	5.80e-01	-7.54e-02	8.00e-01
GO:0009611 response to wounding	19	5.70e-01	-7.52e-02	7.96e-01
GO:0031901 early endosome membrane	76	2.58e-01	7.52e-02	5.47e-01
GO:0006915 apoptotic process	135	1.33e-01	7.51e-02	3.95e-01
GO:0005540 hyaluronic acid binding	13	6.40e-01	-7.50e-02	8.26e-01
GO:0031333 negative regulation of protein-containing complex assembly	16	6.04e-01	7.49e-02	8.11e-01
GO:0006865 amino acid transport	10	6.82e-01	-7.48e-02	8.47e-01
GO:0001755 neural crest cell migration	27	5.03e-01	-7.44e-02	7.60e-01
GO:0051604 protein maturation	20	5.65e-01	-7.44e-02	7.92e-01
GO:0030374 nuclear receptor coactivator activity	30	4.81e-01	-7.44e-02	7.42e-01
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity	19	5.76e-01	-7.41e-02	7.99e-01
GO:0030139 endocytic vesicle	38	4.29e-01	-7.41e-02	7.04e-01
GO:0061630 ubiquitin protein ligase activity	177	9.30e-02	-7.34e-02	3.18e-01
GO:0001782 B cell homeostasis	12	6.60e-01	-7.33e-02	8.37e-01
GO:0042127 regulation of cell population proliferation	45	3.95e-01	-7.33e-02	6.78e-01
GO:0034244 negative regulation of transcription elongation by RNA polymerase II	13	6.47e-01	7.33e-02	8.32e-01
GO:0005813 centrosome	344	2.01e-02	7.32e-02	1.39e-01
GO:0051781 positive regulation of cell division	13	6.48e-01	7.32e-02	8.32e-01
GO:0000794 condensed nuclear chromosome	20	5.73e-01	-7.28e-02	7.97e-01
GO:0005634 nucleus	2127	7.96e-08	-7.28e-02	7.51e-06
GO:0000278 mitotic cell cycle	53	3.60e-01	-7.28e-02	6.61e-01
GO:0030838 positive regulation of actin filament polymerization	27	5.13e-01	7.27e-02	7.65e-01
GO:0016235 aggresome	17	6.04e-01	-7.27e-02	8.11e-01
GO:0140311 protein sequestering activity	18	5.95e-01	7.25e-02	8.07e-01
GO:0007608 sensory perception of smell	11	6.78e-01	7.22e-02	8.45e-01
GO:0048706 embryonic skeletal system development	16	6.17e-01	7.21e-02	8.17e-01
GO:0055038 recycling endosome membrane	43	4.15e-01	7.20e-02	6.94e-01
GO:0005834 heterotrimeric G-protein complex	19	5.87e-01	-7.20e-02	8.04e-01
GO:0097190 apoptotic signaling pathway	20	5.79e-01	7.17e-02	8.00e-01
GO:0070062 extracellular exosome	38	4.45e-01	-7.17e-02	7.09e-01
GO:0072659 protein localization to plasma membrane	75	2.85e-01	7.14e-02	5.75e-01
GO:0051321 meiotic cell cycle	21	5.71e-01	-7.14e-02	7.96e-01
GO:0007275 multicellular organism development	27	5.21e-01	-7.14e-02	7.69e-01
GO:0060339 negative regulation of type I interferon-mediated signaling pathway	13	6.57e-01	7.12e-02	8.37e-01
GO:0016477 cell migration	135	1.54e-01	-7.12e-02	4.25e-01
GO:0051965 positive regulation of synapse assembly	22	5.64e-01	7.10e-02	7.92e-01
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process	155	1.29e-01	7.08e-02	3.88e-01
GO:0001726 ruffle	43	4.23e-01	-7.07e-02	6.98e-01
GO:0019706 protein-cysteine S-palmitoyltransferase activity	17	6.14e-01	7.07e-02	8.17e-01
GO:0031369 translation initiation factor binding	12	6.72e-01	-7.06e-02	8.43e-01
GO:0038023 signaling receptor activity	40	4.41e-01	-7.05e-02	7.08e-01
GO:0006270 DNA replication initiation	19	5.95e-01	-7.04e-02	8.07e-01
GO:0043021 ribonucleoprotein complex binding	23	5.60e-01	-7.03e-02	7.87e-01
GO:0043524 negative regulation of neuron apoptotic process	52	3.81e-01	-7.03e-02	6.71e-01
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding	13	6.61e-01	7.03e-02	8.37e-01
GO:0002931 response to ischemia	10	7.01e-01	-7.02e-02	8.57e-01
GO:0030501 positive regulation of bone mineralization	14	6.50e-01	7.01e-02	8.33e-01
GO:0003341 cilium movement	10	7.02e-01	6.98e-02	8.57e-01
GO:0006672 ceramide metabolic process	10	7.02e-01	6.98e-02	8.57e-01
GO:0004930 G protein-coupled receptor activity	55	3.73e-01	-6.96e-02	6.69e-01
GO:0043235 receptor complex	77	2.92e-01	-6.95e-02	5.82e-01
GO:0032729 positive regulation of type II interferon production	22	5.73e-01	6.95e-02	7.97e-01
GO:0031463 Cul3-RING ubiquitin ligase complex	41	4.42e-01	6.95e-02	7.08e-01
GO:0043488 regulation of mRNA stability	16	6.30e-01	-6.95e-02	8.22e-01
GO:0007623 circadian rhythm	18	6.11e-01	6.92e-02	8.16e-01
GO:0051894 positive regulation of focal adhesion assembly	15	6.43e-01	6.90e-02	8.29e-01
GO:0032420 stereocilium	14	6.55e-01	6.90e-02	8.37e-01
GO:0045202 synapse	164	1.29e-01	6.88e-02	3.89e-01
GO:0045177 apical part of cell	34	4.88e-01	6.87e-02	7.48e-01
GO:0060047 heart contraction	10	7.07e-01	6.87e-02	8.59e-01
GO:0032715 negative regulation of interleukin-6 production	14	6.57e-01	-6.86e-02	8.37e-01
GO:0043022 ribosome binding	46	4.21e-01	6.86e-02	6.98e-01
GO:0048012 hepatocyte growth factor receptor signaling pathway	18	6.15e-01	-6.86e-02	8.17e-01
GO:0098686 hippocampal mossy fiber to CA3 synapse	18	6.15e-01	-6.84e-02	8.17e-01
GO:0000287 magnesium ion binding	149	1.51e-01	6.84e-02	4.25e-01
GO:0007286 spermatid development	25	5.54e-01	6.84e-02	7.83e-01
GO:0000077 DNA damage checkpoint signaling	26	5.47e-01	-6.83e-02	7.79e-01
GO:0006955 immune response	41	4.49e-01	-6.83e-02	7.14e-01
GO:0070372 regulation of ERK1 and ERK2 cascade	13	6.71e-01	-6.81e-02	8.41e-01
GO:0048839 inner ear development	12	6.84e-01	-6.78e-02	8.47e-01
GO:0009966 regulation of signal transduction	38	4.71e-01	-6.77e-02	7.36e-01
GO:0098586 cellular response to virus	22	5.83e-01	-6.76e-02	8.02e-01
GO:0031647 regulation of protein stability	57	3.79e-01	-6.75e-02	6.71e-01
GO:0006094 gluconeogenesis	21	5.93e-01	6.73e-02	8.07e-01
GO:0003723 RNA binding	372	2.68e-02	-6.72e-02	1.65e-01
GO:0031267 small GTPase binding	166	1.37e-01	-6.70e-02	4.04e-01
GO:0033017 sarcoplasmic reticulum membrane	10	7.14e-01	-6.70e-02	8.64e-01
GO:0004535 poly(A)-specific ribonuclease activity	10	7.14e-01	6.69e-02	8.64e-01
GO:0007288 sperm axoneme assembly	17	6.34e-01	6.68e-02	8.23e-01
GO:0001707 mesoderm formation	15	6.55e-01	-6.67e-02	8.37e-01
GO:0007389 pattern specification process	14	6.66e-01	6.66e-02	8.39e-01
GO:0016757 glycosyltransferase activity	14	6.67e-01	-6.64e-02	8.39e-01
GO:0030878 thyroid gland development	14	6.67e-01	-6.64e-02	8.39e-01
GO:0032731 positive regulation of interleukin-1 beta production	12	6.92e-01	-6.60e-02	8.50e-01
GO:0042149 cellular response to glucose starvation	28	5.46e-01	-6.59e-02	7.79e-01
GO:0030970 retrograde protein transport, ER to cytosol	12	6.93e-01	6.58e-02	8.51e-01
GO:0007032 endosome organization	28	5.49e-01	-6.55e-02	7.80e-01
GO:0033627 cell adhesion mediated by integrin	22	5.95e-01	-6.55e-02	8.07e-01
GO:0090398 cellular senescence	19	6.23e-01	-6.52e-02	8.20e-01
GO:0002062 chondrocyte differentiation	22	5.97e-01	-6.52e-02	8.07e-01
GO:0071456 cellular response to hypoxia	34	5.11e-01	-6.52e-02	7.65e-01
GO:0022857 transmembrane transporter activity	39	4.84e-01	-6.48e-02	7.44e-01
GO:0016973 poly(A)+ mRNA export from nucleus	13	6.86e-01	-6.47e-02	8.48e-01
GO:0016853 isomerase activity	19	6.25e-01	-6.47e-02	8.20e-01
GO:0042733 embryonic digit morphogenesis	30	5.40e-01	6.47e-02	7.74e-01
GO:0004714 transmembrane receptor protein tyrosine kinase activity	15	6.65e-01	6.46e-02	8.39e-01
GO:0042274 ribosomal small subunit biogenesis	44	4.59e-01	6.45e-02	7.22e-01
GO:0016042 lipid catabolic process	29	5.51e-01	6.40e-02	7.81e-01
GO:0030521 androgen receptor signaling pathway	12	7.01e-01	6.39e-02	8.57e-01
GO:0030032 lamellipodium assembly	21	6.13e-01	-6.39e-02	8.17e-01
GO:0004435 phosphatidylinositol phospholipase C activity	12	7.04e-01	6.34e-02	8.58e-01
GO:0030833 regulation of actin filament polymerization	21	6.15e-01	-6.34e-02	8.17e-01
GO:0031290 retinal ganglion cell axon guidance	12	7.04e-01	-6.33e-02	8.58e-01
GO:0071320 cellular response to cAMP	19	6.33e-01	6.32e-02	8.23e-01
GO:0043065 positive regulation of apoptotic process	121	2.32e-01	-6.30e-02	5.23e-01
GO:0032418 lysosome localization	23	6.01e-01	-6.30e-02	8.10e-01
GO:0006914 autophagy	44	4.71e-01	6.28e-02	7.37e-01
GO:0051259 protein complex oligomerization	14	6.84e-01	6.27e-02	8.47e-01
GO:0030335 positive regulation of cell migration	109	2.60e-01	-6.25e-02	5.49e-01
GO:1990166 protein localization to site of double-strand break	10	7.32e-01	6.25e-02	8.72e-01
GO:0034504 protein localization to nucleus	20	6.29e-01	-6.24e-02	8.22e-01
GO:0051539 4 iron, 4 sulfur cluster binding	33	5.35e-01	6.24e-02	7.74e-01
GO:0035924 cellular response to vascular endothelial growth factor stimulus	15	6.76e-01	6.24e-02	8.45e-01
GO:0031297 replication fork processing	26	5.82e-01	6.23e-02	8.02e-01
GO:0106310 protein serine kinase activity	38	5.09e-01	-6.19e-02	7.64e-01
GO:1904263 positive regulation of TORC1 signaling	35	5.27e-01	6.18e-02	7.74e-01
GO:0010906 regulation of glucose metabolic process	10	7.35e-01	-6.18e-02	8.72e-01
GO:0051315 attachment of mitotic spindle microtubules to kinetochore	10	7.36e-01	6.16e-02	8.72e-01
GO:0042100 B cell proliferation	14	6.90e-01	-6.15e-02	8.50e-01
GO:0071949 FAD binding	27	5.81e-01	6.14e-02	8.01e-01
GO:0051087 protein-folding chaperone binding	55	4.32e-01	6.13e-02	7.07e-01
GO:0070301 cellular response to hydrogen peroxide	23	6.13e-01	6.09e-02	8.17e-01
GO:0007052 mitotic spindle organization	34	5.40e-01	-6.08e-02	7.74e-01
GO:0001935 endothelial cell proliferation	12	7.16e-01	6.07e-02	8.65e-01
GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	80	3.49e-01	-6.06e-02	6.50e-01
GO:0038066 p38MAPK cascade	12	7.18e-01	-6.01e-02	8.67e-01
GO:0010975 regulation of neuron projection development	16	6.78e-01	6.00e-02	8.45e-01
GO:0019894 kinesin binding	21	6.34e-01	-5.99e-02	8.23e-01
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding	21	6.35e-01	5.98e-02	8.24e-01
GO:0005901 caveola	28	5.86e-01	5.95e-02	8.03e-01
GO:0035987 endodermal cell differentiation	22	6.30e-01	-5.93e-02	8.22e-01
GO:0019900 kinase binding	48	4.78e-01	-5.93e-02	7.39e-01
GO:0005876 spindle microtubule	20	6.47e-01	5.93e-02	8.31e-01
GO:0016791 phosphatase activity	15	6.91e-01	5.92e-02	8.50e-01
GO:0030890 positive regulation of B cell proliferation	21	6.39e-01	-5.91e-02	8.26e-01
GO:0071168 protein localization to chromatin	17	6.73e-01	-5.91e-02	8.44e-01
GO:0042130 negative regulation of T cell proliferation	12	7.24e-01	-5.89e-02	8.70e-01
GO:0050840 extracellular matrix binding	16	6.85e-01	5.86e-02	8.47e-01
GO:0007160 cell-matrix adhesion	40	5.27e-01	-5.78e-02	7.74e-01
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway	19	6.63e-01	-5.78e-02	8.38e-01
GO:0004843 cysteine-type deubiquitinase activity	57	4.53e-01	-5.75e-02	7.20e-01
GO:0019888 protein phosphatase regulator activity	16	6.92e-01	-5.72e-02	8.50e-01
GO:0004879 nuclear receptor activity	38	5.43e-01	-5.70e-02	7.77e-01
GO:0035591 signaling adaptor activity	40	5.33e-01	5.69e-02	7.74e-01
GO:0042169 SH2 domain binding	20	6.61e-01	-5.67e-02	8.37e-01
GO:0030217 T cell differentiation	18	6.77e-01	-5.67e-02	8.45e-01
GO:0006417 regulation of translation	44	5.15e-01	-5.67e-02	7.66e-01
GO:0007254 JNK cascade	26	6.18e-01	-5.66e-02	8.17e-01
GO:0006605 protein targeting	18	6.80e-01	-5.62e-02	8.45e-01
GO:0140627 ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	10	7.59e-01	5.61e-02	8.89e-01
GO:0098982 GABA-ergic synapse	27	6.17e-01	5.56e-02	8.17e-01
GO:0045296 cadherin binding	28	6.11e-01	-5.56e-02	8.16e-01
GO:0045444 fat cell differentiation	44	5.24e-01	5.56e-02	7.72e-01
GO:0001968 fibronectin binding	10	7.62e-01	-5.54e-02	8.91e-01
GO:0004721 phosphoprotein phosphatase activity	21	6.61e-01	-5.53e-02	8.37e-01
GO:0003697 single-stranded DNA binding	67	4.38e-01	-5.49e-02	7.08e-01
GO:0005770 late endosome	75	4.12e-01	5.48e-02	6.92e-01
GO:0006486 protein glycosylation	45	5.29e-01	-5.43e-02	7.74e-01
GO:0005524 ATP binding	894	6.56e-03	-5.42e-02	7.33e-02
GO:0032496 response to lipopolysaccharide	37	5.69e-01	5.42e-02	7.95e-01
GO:0032760 positive regulation of tumor necrosis factor production	34	5.86e-01	5.40e-02	8.03e-01
GO:0001525 angiogenesis	88	3.82e-01	-5.39e-02	6.71e-01
GO:0000712 resolution of meiotic recombination intermediates	14	7.28e-01	5.38e-02	8.71e-01
GO:0051607 defense response to virus	55	4.91e-01	5.38e-02	7.49e-01
GO:1901981 phosphatidylinositol phosphate binding	16	7.11e-01	5.36e-02	8.63e-01
GO:0030866 cortical actin cytoskeleton organization	20	6.80e-01	-5.33e-02	8.45e-01
GO:0035861 site of double-strand break	58	4.84e-01	-5.32e-02	7.44e-01
GO:0098655 monoatomic cation transmembrane transport	14	7.33e-01	5.27e-02	8.72e-01
GO:0045765 regulation of angiogenesis	10	7.73e-01	-5.26e-02	8.97e-01
GO:0035904 aorta development	15	7.25e-01	-5.25e-02	8.70e-01
GO:0005654 nucleoplasm	1531	8.07e-04	-5.23e-02	1.76e-02
GO:0030218 erythrocyte differentiation	28	6.32e-01	5.23e-02	8.22e-01
GO:0045766 positive regulation of angiogenesis	53	5.11e-01	5.23e-02	7.65e-01
GO:0019005 SCF ubiquitin ligase complex	43	5.53e-01	5.23e-02	7.83e-01
GO:0030183 B cell differentiation	27	6.39e-01	-5.22e-02	8.26e-01
GO:0046513 ceramide biosynthetic process	19	6.94e-01	-5.21e-02	8.51e-01
GO:0006289 nucleotide-excision repair	22	6.77e-01	5.13e-02	8.45e-01
GO:0043130 ubiquitin binding	61	4.90e-01	-5.11e-02	7.49e-01
GO:0030307 positive regulation of cell growth	36	5.99e-01	-5.07e-02	8.09e-01
GO:0098794 postsynapse	66	4.77e-01	-5.07e-02	7.39e-01
GO:0006783 heme biosynthetic process	10	7.83e-01	5.04e-02	9.04e-01
GO:0060090 molecular adaptor activity	75	4.54e-01	-5.00e-02	7.20e-01
GO:0071539 protein localization to centrosome	20	6.99e-01	5.00e-02	8.55e-01
GO:0005006 epidermal growth factor receptor activity	15	7.39e-01	-4.98e-02	8.73e-01
GO:0050769 positive regulation of neurogenesis	12	7.66e-01	-4.97e-02	8.91e-01
GO:0031624 ubiquitin conjugating enzyme binding	17	7.24e-01	-4.94e-02	8.70e-01
GO:0043197 dendritic spine	45	5.67e-01	-4.94e-02	7.94e-01
GO:0098978 glutamatergic synapse	231	1.98e-01	-4.93e-02	4.85e-01
GO:0009982 pseudouridine synthase activity	12	7.69e-01	-4.90e-02	8.94e-01
GO:0050804 modulation of chemical synaptic transmission	35	6.16e-01	-4.90e-02	8.17e-01
GO:0038191 neuropilin binding	10	7.90e-01	-4.87e-02	9.07e-01
GO:0032040 small-subunit processome	59	5.20e-01	4.85e-02	7.68e-01
GO:0016020 membrane	945	1.30e-02	4.83e-02	1.06e-01
GO:0071007 U2-type catalytic step 2 spliceosome	24	6.83e-01	4.82e-02	8.47e-01
GO:0031965 nuclear membrane	120	3.65e-01	-4.80e-02	6.61e-01
GO:0036464 cytoplasmic ribonucleoprotein granule	36	6.20e-01	4.78e-02	8.17e-01
GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity	34	6.30e-01	-4.78e-02	8.22e-01
GO:0002102 podosome	18	7.26e-01	-4.77e-02	8.70e-01
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	28	6.63e-01	4.76e-02	8.38e-01
GO:0006986 response to unfolded protein	12	7.76e-01	4.75e-02	8.99e-01
GO:0038109 Kit signaling pathway	15	7.51e-01	-4.74e-02	8.83e-01
GO:0005847 mRNA cleavage and polyadenylation specificity factor complex	11	7.86e-01	4.72e-02	9.06e-01
GO:0007528 neuromuscular junction development	15	7.52e-01	4.72e-02	8.83e-01
GO:0043231 intracellular membrane-bounded organelle	115	3.83e-01	-4.72e-02	6.71e-01
GO:0043025 neuronal cell body	84	4.56e-01	-4.71e-02	7.21e-01
GO:0032869 cellular response to insulin stimulus	34	6.37e-01	-4.69e-02	8.24e-01
GO:0007338 single fertilization	19	7.25e-01	-4.66e-02	8.70e-01
GO:0002020 protease binding	44	5.95e-01	-4.63e-02	8.07e-01
GO:0042645 mitochondrial nucleoid	37	6.28e-01	-4.60e-02	8.22e-01
GO:0050714 positive regulation of protein secretion	19	7.29e-01	4.59e-02	8.71e-01
GO:0007420 brain development	78	4.88e-01	-4.54e-02	7.48e-01
GO:0008542 visual learning	20	7.25e-01	4.54e-02	8.70e-01
GO:0000922 spindle pole	68	5.18e-01	4.54e-02	7.66e-01
GO:0016579 protein deubiquitination	28	6.78e-01	4.53e-02	8.45e-01
GO:0008285 negative regulation of cell population proliferation	117	4.01e-01	-4.50e-02	6.82e-01
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding	41	6.20e-01	4.48e-02	8.17e-01
GO:0001947 heart looping	23	7.11e-01	4.46e-02	8.63e-01
GO:0061025 membrane fusion	21	7.24e-01	4.46e-02	8.70e-01
GO:0008305 integrin complex	17	7.51e-01	4.45e-02	8.83e-01
GO:0006367 transcription initiation at RNA polymerase II promoter	20	7.31e-01	-4.45e-02	8.72e-01
GO:0048488 synaptic vesicle endocytosis	21	7.25e-01	4.44e-02	8.70e-01
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity	20	7.32e-01	4.43e-02	8.72e-01
GO:0005643 nuclear pore	33	6.61e-01	-4.41e-02	8.37e-01
GO:0070382 exocytic vesicle	10	8.10e-01	4.40e-02	9.15e-01
GO:0045943 positive regulation of transcription by RNA polymerase I	11	8.01e-01	-4.38e-02	9.12e-01
GO:0006400 tRNA modification	11	8.01e-01	-4.38e-02	9.12e-01
GO:1901673 regulation of mitotic spindle assembly	16	7.62e-01	4.37e-02	8.91e-01
GO:0042552 myelination	28	6.90e-01	-4.36e-02	8.50e-01
GO:0006606 protein import into nucleus	63	5.50e-01	-4.36e-02	7.80e-01
GO:0030199 collagen fibril organization	32	6.70e-01	-4.35e-02	8.41e-01
GO:0006446 regulation of translational initiation	17	7.56e-01	4.35e-02	8.87e-01
GO:0051865 protein autoubiquitination	38	6.44e-01	4.34e-02	8.29e-01
GO:0099523 presynaptic cytosol	11	8.04e-01	4.32e-02	9.12e-01
GO:0008201 heparin binding	57	5.73e-01	-4.32e-02	7.97e-01
GO:0051382 kinetochore assembly	11	8.05e-01	4.30e-02	9.12e-01
GO:0035116 embryonic hindlimb morphogenesis	11	8.06e-01	-4.28e-02	9.13e-01
GO:0050729 positive regulation of inflammatory response	22	7.29e-01	4.27e-02	8.71e-01
GO:0001541 ovarian follicle development	19	7.48e-01	4.27e-02	8.83e-01
GO:0030175 filopodium	29	6.92e-01	-4.25e-02	8.50e-01
GO:0047496 vesicle transport along microtubule	11	8.08e-01	-4.24e-02	9.13e-01
GO:0048471 perinuclear region of cytoplasm	289	2.19e-01	4.22e-02	5.15e-01
GO:0005179 hormone activity	14	7.86e-01	-4.20e-02	9.06e-01
GO:0032259 methylation	76	5.28e-01	4.19e-02	7.74e-01
GO:0008021 synaptic vesicle	47	6.20e-01	4.19e-02	8.17e-01
GO:0007369 gastrulation	10	8.19e-01	-4.18e-02	9.21e-01
GO:0017025 TBP-class protein binding	18	7.60e-01	-4.17e-02	8.89e-01
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	16	7.74e-01	4.16e-02	8.97e-01
GO:0006611 protein export from nucleus	22	7.37e-01	-4.14e-02	8.73e-01
GO:0008076 voltage-gated potassium channel complex	20	7.49e-01	4.14e-02	8.83e-01
GO:0030073 insulin secretion	13	7.97e-01	-4.12e-02	9.12e-01
GO:1903078 positive regulation of protein localization to plasma membrane	21	7.44e-01	-4.12e-02	8.79e-01
GO:2000786 positive regulation of autophagosome assembly	14	7.90e-01	-4.11e-02	9.07e-01
GO:0001664 G protein-coupled receptor binding	22	7.39e-01	-4.11e-02	8.73e-01
GO:0004222 metalloendopeptidase activity	50	6.17e-01	-4.10e-02	8.17e-01
GO:0000993 RNA polymerase II complex binding	23	7.34e-01	-4.09e-02	8.72e-01
GO:0019904 protein domain specific binding	105	4.70e-01	-4.09e-02	7.36e-01
GO:0001817 regulation of cytokine production	26	7.18e-01	-4.09e-02	8.67e-01
GO:0010629 negative regulation of gene expression	103	4.74e-01	-4.08e-02	7.37e-01
GO:0042734 presynaptic membrane	37	6.69e-01	-4.06e-02	8.41e-01
GO:0006607 NLS-bearing protein import into nucleus	10	8.24e-01	-4.05e-02	9.23e-01
GO:0016485 protein processing	40	6.60e-01	4.03e-02	8.37e-01
GO:0008180 COP9 signalosome	21	7.50e-01	4.02e-02	8.83e-01
GO:0031648 protein destabilization	32	6.96e-01	-4.00e-02	8.52e-01
GO:0005776 autophagosome	41	6.61e-01	3.96e-02	8.37e-01
GO:0000226 microtubule cytoskeleton organization	69	5.70e-01	-3.96e-02	7.96e-01
GO:0070085 glycosylation	14	7.98e-01	3.95e-02	9.12e-01
GO:0034976 response to endoplasmic reticulum stress	33	6.94e-01	3.95e-02	8.51e-01
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis	14	7.99e-01	3.93e-02	9.12e-01
GO:0010008 endosome membrane	86	5.30e-01	3.92e-02	7.74e-01
GO:0034707 chloride channel complex	12	8.14e-01	-3.92e-02	9.18e-01
GO:0003774 cytoskeletal motor activity	13	8.07e-01	-3.90e-02	9.13e-01
GO:0000176 nuclear exosome (RNase complex)	12	8.15e-01	3.90e-02	9.18e-01
GO:0014704 intercalated disc	14	8.01e-01	-3.90e-02	9.12e-01
GO:0030971 receptor tyrosine kinase binding	32	7.05e-01	3.87e-02	8.58e-01
GO:0032588 trans-Golgi network membrane	26	7.33e-01	-3.87e-02	8.72e-01
GO:0045111 intermediate filament cytoskeleton	23	7.49e-01	-3.86e-02	8.83e-01
GO:0051219 phosphoprotein binding	20	7.65e-01	-3.86e-02	8.91e-01
GO:0007339 binding of sperm to zona pellucida	11	8.25e-01	3.86e-02	9.23e-01
GO:0042254 ribosome biogenesis	16	7.90e-01	-3.85e-02	9.07e-01
GO:0051453 regulation of intracellular pH	14	8.03e-01	3.84e-02	9.12e-01
GO:0005730 nucleolus	442	1.69e-01	-3.83e-02	4.43e-01
GO:0030206 chondroitin sulfate biosynthetic process	11	8.26e-01	-3.83e-02	9.23e-01
GO:0008543 fibroblast growth factor receptor signaling pathway	36	6.91e-01	-3.83e-02	8.50e-01
GO:0031573 mitotic intra-S DNA damage checkpoint signaling	11	8.26e-01	3.82e-02	9.23e-01
GO:0030163 protein catabolic process	31	7.13e-01	3.81e-02	8.64e-01
GO:0000724 double-strand break repair via homologous recombination	71	5.80e-01	-3.81e-02	8.00e-01
GO:0008340 determination of adult lifespan	21	7.64e-01	3.79e-02	8.91e-01
GO:0001222 transcription corepressor binding	27	7.36e-01	-3.76e-02	8.72e-01
GO:0008198 ferrous iron binding	12	8.22e-01	-3.75e-02	9.23e-01
GO:0043123 positive regulation of canonical NF-kappaB signal transduction	75	5.75e-01	3.75e-02	7.98e-01
GO:0045824 negative regulation of innate immune response	16	7.95e-01	3.75e-02	9.10e-01
GO:0005689 U12-type spliceosomal complex	20	7.72e-01	3.74e-02	8.97e-01
GO:0015026 coreceptor activity	13	8.16e-01	3.74e-02	9.18e-01
GO:0061462 protein localization to lysosome	10	8.38e-01	-3.73e-02	9.32e-01
GO:0007165 signal transduction	262	3.02e-01	-3.72e-02	5.96e-01
GO:0016197 endosomal transport	27	7.39e-01	-3.71e-02	8.73e-01
GO:0000086 G2/M transition of mitotic cell cycle	25	7.52e-01	3.66e-02	8.83e-01
GO:0006099 tricarboxylic acid cycle	19	7.84e-01	-3.64e-02	9.04e-01
GO:0001501 skeletal system development	34	7.14e-01	-3.63e-02	8.64e-01
GO:0042803 protein homodimerization activity	369	2.35e-01	3.61e-02	5.25e-01
GO:0006954 inflammatory response	81	5.75e-01	-3.61e-02	7.98e-01
GO:0006303 double-strand break repair via nonhomologous end joining	20	7.81e-01	-3.60e-02	9.03e-01
GO:0098719 sodium ion import across plasma membrane	10	8.44e-01	-3.59e-02	9.35e-01
GO:0016925 protein sumoylation	19	7.87e-01	3.58e-02	9.06e-01
GO:0045121 membrane raft	75	5.95e-01	-3.55e-02	8.07e-01
GO:0043014 alpha-tubulin binding	23	7.68e-01	-3.55e-02	8.94e-01
GO:0061564 axon development	13	8.25e-01	3.55e-02	9.23e-01
GO:0003684 damaged DNA binding	34	7.23e-01	-3.52e-02	8.70e-01
GO:0009267 cellular response to starvation	48	6.74e-01	3.51e-02	8.44e-01
GO:0098839 postsynaptic density membrane	33	7.30e-01	3.48e-02	8.71e-01
GO:0030276 clathrin binding	17	8.04e-01	-3.48e-02	9.12e-01
GO:0001837 epithelial to mesenchymal transition	17	8.05e-01	-3.46e-02	9.12e-01
GO:0050821 protein stabilization	109	5.33e-01	3.46e-02	7.74e-01
GO:0035176 social behavior	16	8.11e-01	-3.46e-02	9.15e-01
GO:0035024 negative regulation of Rho protein signal transduction	14	8.24e-01	-3.43e-02	9.23e-01
GO:0044325 transmembrane transporter binding	56	6.58e-01	3.42e-02	8.37e-01
GO:0042626 ATPase-coupled transmembrane transporter activity	18	8.03e-01	-3.40e-02	9.12e-01
GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels	16	8.14e-01	3.40e-02	9.18e-01
GO:0007605 sensory perception of sound	54	6.68e-01	-3.38e-02	8.39e-01
GO:0008284 positive regulation of cell population proliferation	156	4.68e-01	3.37e-02	7.34e-01
GO:0019899 enzyme binding	111	5.44e-01	3.34e-02	7.77e-01
GO:0031116 positive regulation of microtubule polymerization	11	8.49e-01	3.32e-02	9.36e-01
GO:0007080 mitotic metaphase chromosome alignment	23	7.83e-01	3.32e-02	9.04e-01
GO:0007015 actin filament organization	73	6.25e-01	-3.31e-02	8.20e-01
GO:0005385 zinc ion transmembrane transporter activity	15	8.25e-01	-3.30e-02	9.23e-01
GO:0006268 DNA unwinding involved in DNA replication	14	8.31e-01	3.30e-02	9.26e-01
GO:0032874 positive regulation of stress-activated MAPK cascade	11	8.51e-01	-3.28e-02	9.37e-01
GO:0030198 extracellular matrix organization	75	6.24e-01	-3.27e-02	8.20e-01
GO:0070131 positive regulation of mitochondrial translation	10	8.60e-01	-3.22e-02	9.43e-01
GO:0048863 stem cell differentiation	21	7.99e-01	-3.21e-02	9.12e-01
GO:0006897 endocytosis	91	6.00e-01	3.18e-02	8.10e-01
GO:0071560 cellular response to transforming growth factor beta stimulus	16	8.26e-01	3.18e-02	9.23e-01
GO:0072686 mitotic spindle	69	6.49e-01	-3.17e-02	8.33e-01
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway	43	7.20e-01	-3.16e-02	8.68e-01
GO:0046540 U4/U6 x U5 tri-snRNP complex	23	7.94e-01	3.15e-02	9.10e-01
GO:0005007 fibroblast growth factor receptor activity	14	8.38e-01	-3.15e-02	9.32e-01
GO:0032465 regulation of cytokinesis	23	7.95e-01	-3.14e-02	9.10e-01
GO:0070527 platelet aggregation	16	8.28e-01	3.13e-02	9.24e-01
GO:0005741 mitochondrial outer membrane	95	6.06e-01	3.07e-02	8.13e-01
GO:0007613 memory	28	7.80e-01	-3.05e-02	9.03e-01
GO:0045747 positive regulation of Notch signaling pathway	22	8.05e-01	-3.04e-02	9.12e-01
GO:0097191 extrinsic apoptotic signaling pathway	20	8.18e-01	2.98e-02	9.20e-01
GO:0006402 mRNA catabolic process	14	8.48e-01	-2.97e-02	9.36e-01
GO:0043124 negative regulation of canonical NF-kappaB signal transduction	36	7.63e-01	-2.91e-02	8.91e-01
GO:0046329 negative regulation of JNK cascade	12	8.62e-01	2.91e-02	9.43e-01
GO:0006493 protein O-linked glycosylation	29	7.86e-01	-2.91e-02	9.06e-01
GO:0000082 G1/S transition of mitotic cell cycle	40	7.53e-01	-2.88e-02	8.84e-01
GO:0010592 positive regulation of lamellipodium assembly	10	8.75e-01	-2.88e-02	9.46e-01
GO:0090201 negative regulation of release of cytochrome c from mitochondria	11	8.69e-01	-2.87e-02	9.46e-01
GO:0006730 one-carbon metabolic process	13	8.59e-01	2.86e-02	9.42e-01
GO:0033344 cholesterol efflux	11	8.70e-01	2.84e-02	9.46e-01
GO:0007268 chemical synaptic transmission	32	7.81e-01	-2.84e-02	9.03e-01
GO:0019903 protein phosphatase binding	49	7.32e-01	-2.83e-02	8.72e-01
GO:0005768 endosome	113	6.10e-01	2.78e-02	8.16e-01
GO:0030140 trans-Golgi network transport vesicle	11	8.73e-01	-2.78e-02	9.46e-01
GO:0042383 sarcolemma	37	7.70e-01	-2.77e-02	8.95e-01
GO:0016358 dendrite development	19	8.37e-01	-2.74e-02	9.31e-01
GO:0007214 gamma-aminobutyric acid signaling pathway	11	8.76e-01	2.72e-02	9.46e-01
GO:0001736 establishment of planar polarity	12	8.71e-01	2.71e-02	9.46e-01
GO:0048015 phosphatidylinositol-mediated signaling	18	8.46e-01	-2.65e-02	9.35e-01
GO:0010811 positive regulation of cell-substrate adhesion	13	8.69e-01	2.64e-02	9.46e-01
GO:0006457 protein folding	81	6.83e-01	2.63e-02	8.47e-01
GO:0042391 regulation of membrane potential	12	8.75e-01	-2.62e-02	9.46e-01
GO:0043066 negative regulation of apoptotic process	153	5.77e-01	-2.61e-02	8.00e-01
GO:0043015 gamma-tubulin binding	21	8.36e-01	2.60e-02	9.31e-01
GO:1990904 ribonucleoprotein complex	104	6.54e-01	2.55e-02	8.37e-01
GO:0098793 presynapse	63	7.27e-01	2.54e-02	8.71e-01
GO:0019915 lipid storage	11	8.84e-01	2.54e-02	9.48e-01
GO:0046034 ATP metabolic process	13	8.75e-01	-2.53e-02	9.46e-01
GO:0060391 positive regulation of SMAD protein signal transduction	11	8.86e-01	-2.50e-02	9.49e-01
GO:0048872 homeostasis of number of cells	14	8.73e-01	2.47e-02	9.46e-01
GO:0042470 melanosome	28	8.21e-01	2.47e-02	9.23e-01
GO:0005680 anaphase-promoting complex	13	8.78e-01	-2.47e-02	9.46e-01
GO:0050890 cognition	18	8.57e-01	2.46e-02	9.42e-01
GO:0000159 protein phosphatase type 2A complex	12	8.83e-01	-2.46e-02	9.47e-01
GO:0001778 plasma membrane repair	16	8.67e-01	-2.42e-02	9.46e-01
GO:0061077 chaperone-mediated protein folding	16	8.67e-01	2.41e-02	9.46e-01
GO:0007020 microtubule nucleation	14	8.76e-01	2.41e-02	9.46e-01
GO:0016251 RNA polymerase II general transcription initiation factor activity	22	8.45e-01	2.41e-02	9.35e-01
GO:0043010 camera-type eye development	22	8.45e-01	-2.40e-02	9.35e-01
GO:0006310 DNA recombination	23	8.42e-01	2.40e-02	9.35e-01
GO:0032587 ruffle membrane	41	7.92e-01	2.38e-02	9.08e-01
GO:0005615 extracellular space	399	4.18e-01	2.37e-02	6.97e-01
GO:0031410 cytoplasmic vesicle	106	6.75e-01	2.36e-02	8.45e-01
GO:2000045 regulation of G1/S transition of mitotic cell cycle	19	8.59e-01	-2.36e-02	9.42e-01
GO:0005154 epidermal growth factor receptor binding	19	8.59e-01	-2.35e-02	9.42e-01
GO:0051085 chaperone cofactor-dependent protein refolding	23	8.47e-01	-2.33e-02	9.36e-01
GO:0042177 negative regulation of protein catabolic process	23	8.48e-01	-2.31e-02	9.36e-01
GO:0051301 cell division	144	6.35e-01	-2.30e-02	8.23e-01
GO:0032212 positive regulation of telomere maintenance via telomerase	17	8.70e-01	2.30e-02	9.46e-01
GO:0008017 microtubule binding	152	6.31e-01	2.26e-02	8.22e-01
GO:0043536 positive regulation of blood vessel endothelial cell migration	18	8.70e-01	2.23e-02	9.46e-01
GO:0010506 regulation of autophagy	26	8.44e-01	2.23e-02	9.35e-01
GO:0045724 positive regulation of cilium assembly	13	8.90e-01	2.23e-02	9.51e-01
GO:0007283 spermatogenesis	100	7.01e-01	2.22e-02	8.57e-01
GO:0019933 cAMP-mediated signaling	13	8.90e-01	-2.21e-02	9.51e-01
GO:1902476 chloride transmembrane transport	40	8.09e-01	-2.21e-02	9.14e-01
GO:0051879 Hsp90 protein binding	26	8.46e-01	2.20e-02	9.35e-01
GO:0043410 positive regulation of MAPK cascade	62	7.66e-01	-2.19e-02	8.91e-01
GO:0001974 blood vessel remodeling	16	8.80e-01	2.18e-02	9.47e-01
GO:0006284 base-excision repair	17	8.78e-01	-2.16e-02	9.46e-01
GO:0014069 postsynaptic density	98	7.15e-01	-2.14e-02	8.65e-01
GO:0010314 phosphatidylinositol-5-phosphate binding	11	9.03e-01	-2.13e-02	9.58e-01
GO:0046326 positive regulation of D-glucose import	14	8.91e-01	2.11e-02	9.51e-01
GO:0009897 external side of plasma membrane	105	7.10e-01	-2.10e-02	8.63e-01
GO:0048487 beta-tubulin binding	22	8.66e-01	-2.08e-02	9.46e-01
GO:0030674 protein-macromolecule adaptor activity	73	7.60e-01	2.07e-02	8.89e-01
GO:0007346 regulation of mitotic cell cycle	31	8.44e-01	-2.05e-02	9.35e-01
GO:0005635 nuclear envelope	77	7.57e-01	2.04e-02	8.88e-01
GO:0009411 response to UV	23	8.67e-01	2.02e-02	9.46e-01
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity	16	8.90e-01	-2.00e-02	9.51e-01
GO:0045787 positive regulation of cell cycle	13	9.04e-01	1.92e-02	9.58e-01
GO:0044877 protein-containing complex binding	105	7.34e-01	1.92e-02	8.72e-01
GO:0045499 chemorepellent activity	20	8.82e-01	-1.91e-02	9.47e-01
GO:0005096 GTPase activator activity	150	6.87e-01	-1.91e-02	8.48e-01
GO:0098656 monoatomic anion transmembrane transport	18	8.89e-01	-1.90e-02	9.51e-01
GO:0060079 excitatory postsynaptic potential	15	8.99e-01	-1.90e-02	9.57e-01
GO:0070374 positive regulation of ERK1 and ERK2 cascade	60	8.00e-01	-1.89e-02	9.12e-01
GO:0000398 mRNA splicing, via spliceosome	87	7.63e-01	-1.87e-02	8.91e-01
GO:0060348 bone development	26	8.70e-01	1.86e-02	9.46e-01
GO:0007517 muscle organ development	12	9.12e-01	-1.84e-02	9.63e-01
GO:0005886 plasma membrane	1517	2.42e-01	1.84e-02	5.34e-01
GO:0001662 behavioral fear response	12	9.13e-01	-1.83e-02	9.63e-01
GO:0050919 negative chemotaxis	23	8.80e-01	1.82e-02	9.47e-01
GO:0019902 phosphatase binding	23	8.80e-01	1.82e-02	9.47e-01
GO:0051123 RNA polymerase II preinitiation complex assembly	16	9.01e-01	-1.80e-02	9.57e-01
GO:0004722 protein serine/threonine phosphatase activity	33	8.58e-01	1.80e-02	9.42e-01
GO:0048013 ephrin receptor signaling pathway	25	8.76e-01	1.80e-02	9.46e-01
GO:0005509 calcium ion binding	258	6.26e-01	1.77e-02	8.20e-01
GO:0006893 Golgi to plasma membrane transport	19	8.99e-01	-1.68e-02	9.57e-01
GO:0045746 negative regulation of Notch signaling pathway	14	9.14e-01	1.67e-02	9.63e-01
GO:0050766 positive regulation of phagocytosis	14	9.14e-01	1.67e-02	9.63e-01
GO:0006508 proteolysis	172	7.06e-01	-1.67e-02	8.58e-01
GO:0003690 double-stranded DNA binding	35	8.66e-01	1.65e-02	9.46e-01
GO:0043204 perikaryon	35	8.67e-01	-1.64e-02	9.46e-01
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway	14	9.17e-01	-1.62e-02	9.63e-01
GO:0030496 midbody	99	7.81e-01	1.62e-02	9.03e-01
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process	43	8.55e-01	-1.61e-02	9.42e-01
GO:0006869 lipid transport	28	8.83e-01	1.61e-02	9.47e-01
GO:0005868 cytoplasmic dynein complex	14	9.18e-01	1.59e-02	9.63e-01
GO:0055088 lipid homeostasis	19	9.05e-01	1.59e-02	9.58e-01
GO:0045666 positive regulation of neuron differentiation	26	8.89e-01	-1.58e-02	9.51e-01
GO:0004715 non-membrane spanning protein tyrosine kinase activity	20	9.03e-01	1.57e-02	9.58e-01
GO:0019901 protein kinase binding	236	6.80e-01	-1.56e-02	8.45e-01
GO:0005881 cytoplasmic microtubule	30	8.83e-01	-1.55e-02	9.47e-01
GO:0042593 glucose homeostasis	43	8.61e-01	-1.54e-02	9.43e-01
GO:0005507 copper ion binding	24	8.97e-01	-1.52e-02	9.56e-01
GO:0005576 extracellular region	240	6.85e-01	-1.52e-02	8.47e-01
GO:0071711 basement membrane organization	11	9.31e-01	-1.51e-02	9.70e-01
GO:0043627 response to estrogen	10	9.35e-01	1.50e-02	9.70e-01
GO:0004864 protein phosphatase inhibitor activity	13	9.26e-01	1.49e-02	9.68e-01
GO:0016592 mediator complex	28	8.93e-01	-1.47e-02	9.52e-01
GO:0008083 growth factor activity	39	8.77e-01	1.43e-02	9.46e-01
GO:0045087 innate immune response	79	8.33e-01	1.37e-02	9.29e-01
GO:0007186 G protein-coupled receptor signaling pathway	87	8.25e-01	1.37e-02	9.23e-01
GO:0051056 regulation of small GTPase mediated signal transduction	16	9.25e-01	-1.35e-02	9.68e-01
GO:0008237 metallopeptidase activity	12	9.36e-01	-1.33e-02	9.70e-01
GO:0016324 apical plasma membrane	123	7.99e-01	-1.33e-02	9.12e-01
GO:0048477 oogenesis	14	9.32e-01	-1.32e-02	9.70e-01
GO:0046856 phosphatidylinositol dephosphorylation	26	9.08e-01	-1.31e-02	9.61e-01
GO:0005102 signaling receptor binding	81	8.40e-01	-1.30e-02	9.33e-01
GO:0003755 peptidyl-prolyl cis-trans isomerase activity	30	9.04e-01	1.28e-02	9.58e-01
GO:0005829 cytosol	2013	3.58e-01	1.28e-02	6.60e-01
GO:0030687 preribosome, large subunit precursor	12	9.40e-01	-1.26e-02	9.72e-01
GO:0051403 stress-activated MAPK cascade	12	9.41e-01	1.24e-02	9.72e-01
GO:0003688 DNA replication origin binding	12	9.41e-01	-1.23e-02	9.72e-01
GO:0070979 protein K11-linked ubiquitination	22	9.21e-01	1.22e-02	9.65e-01
GO:0005669 transcription factor TFIID complex	22	9.22e-01	-1.21e-02	9.65e-01
GO:0035091 phosphatidylinositol binding	74	8.59e-01	-1.20e-02	9.42e-01
GO:0042752 regulation of circadian rhythm	27	9.16e-01	-1.17e-02	9.63e-01
GO:0008053 mitochondrial fusion	17	9.34e-01	1.16e-02	9.70e-01
GO:0005506 iron ion binding	64	8.72e-01	-1.16e-02	9.46e-01
GO:0005080 protein kinase C binding	17	9.34e-01	-1.16e-02	9.70e-01
GO:0101031 protein folding chaperone complex	18	9.32e-01	-1.16e-02	9.70e-01
GO:0035556 intracellular signal transduction	184	7.88e-01	-1.15e-02	9.06e-01
GO:1990573 potassium ion import across plasma membrane	18	9.34e-01	-1.13e-02	9.70e-01
GO:0032880 regulation of protein localization	41	9.01e-01	1.12e-02	9.57e-01
GO:0051497 negative regulation of stress fiber assembly	18	9.35e-01	1.11e-02	9.70e-01
GO:0031418 L-ascorbic acid binding	14	9.43e-01	1.11e-02	9.72e-01
GO:0006935 chemotaxis	14	9.44e-01	-1.08e-02	9.73e-01
GO:0005815 microtubule organizing center	36	9.11e-01	-1.08e-02	9.63e-01
GO:0036126 sperm flagellum	31	9.18e-01	1.06e-02	9.63e-01
GO:0034450 ubiquitin-ubiquitin ligase activity	12	9.49e-01	1.06e-02	9.76e-01
GO:1990756 ubiquitin-like ligase-substrate adaptor activity	71	8.78e-01	1.05e-02	9.46e-01
GO:0050852 T cell receptor signaling pathway	50	9.00e-01	-1.03e-02	9.57e-01
GO:0006874 intracellular calcium ion homeostasis	37	9.15e-01	-1.01e-02	9.63e-01
GO:0006006 glucose metabolic process	26	9.30e-01	9.96e-03	9.70e-01
GO:0015459 potassium channel regulator activity	14	9.49e-01	9.91e-03	9.76e-01
GO:0071356 cellular response to tumor necrosis factor	37	9.18e-01	9.83e-03	9.63e-01
GO:0005543 phospholipid binding	38	9.17e-01	-9.80e-03	9.63e-01
GO:0051402 neuron apoptotic process	42	9.15e-01	9.49e-03	9.63e-01
GO:0071230 cellular response to amino acid stimulus	29	9.30e-01	-9.49e-03	9.70e-01
GO:0009898 cytoplasmic side of plasma membrane	48	9.11e-01	9.28e-03	9.63e-01
GO:0016779 nucleotidyltransferase activity	10	9.60e-01	9.24e-03	9.85e-01
GO:0006096 glycolytic process	23	9.40e-01	-9.12e-03	9.72e-01
GO:0000175 3’-5’-RNA exonuclease activity	21	9.42e-01	9.10e-03	9.72e-01
GO:0071277 cellular response to calcium ion	31	9.33e-01	8.72e-03	9.70e-01
GO:0016740 transferase activity	23	9.43e-01	-8.59e-03	9.72e-01
GO:0032024 positive regulation of insulin secretion	21	9.47e-01	-8.34e-03	9.75e-01
GO:0030234 enzyme regulator activity	14	9.59e-01	7.93e-03	9.85e-01
GO:0004672 protein kinase activity	64	9.15e-01	7.70e-03	9.63e-01
GO:0019722 calcium-mediated signaling	30	9.45e-01	7.32e-03	9.73e-01
GO:0090102 cochlea development	13	9.64e-01	-7.27e-03	9.87e-01
GO:0045721 negative regulation of gluconeogenesis	10	9.69e-01	7.13e-03	9.90e-01
GO:0051560 mitochondrial calcium ion homeostasis	13	9.65e-01	-7.10e-03	9.87e-01
GO:0005737 cytoplasm	2174	6.00e-01	7.06e-03	8.10e-01
GO:0070050 neuron cellular homeostasis	14	9.65e-01	-6.78e-03	9.87e-01
GO:0007004 telomere maintenance via telomerase	11	9.69e-01	-6.74e-03	9.90e-01
GO:0007611 learning or memory	15	9.64e-01	-6.73e-03	9.87e-01
GO:0005874 microtubule	130	8.97e-01	-6.61e-03	9.56e-01
GO:0045171 intercellular bridge	55	9.33e-01	-6.56e-03	9.70e-01
GO:0006364 rRNA processing	65	9.27e-01	6.55e-03	9.69e-01
GO:0015630 microtubule cytoskeleton	69	9.28e-01	6.29e-03	9.69e-01
GO:0016239 positive regulation of macroautophagy	17	9.65e-01	6.15e-03	9.87e-01
GO:0009986 cell surface	179	8.91e-01	5.95e-03	9.51e-01
GO:0099175 regulation of postsynapse organization	20	9.64e-01	-5.84e-03	9.87e-01
GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process	14	9.71e-01	5.54e-03	9.90e-01
GO:0050699 WW domain binding	11	9.76e-01	5.33e-03	9.92e-01
GO:0010628 positive regulation of gene expression	148	9.13e-01	5.24e-03	9.63e-01
GO:0017116 single-stranded DNA helicase activity	16	9.72e-01	-5.04e-03	9.90e-01
GO:0005254 chloride channel activity	20	9.72e-01	-4.60e-03	9.90e-01
GO:0019955 cytokine binding	11	9.79e-01	4.52e-03	9.93e-01
GO:0097110 scaffold protein binding	28	9.67e-01	-4.47e-03	9.89e-01
GO:0030330 DNA damage response, signal transduction by p53 class mediator	12	9.79e-01	-4.43e-03	9.93e-01
GO:0004693 cyclin-dependent protein serine/threonine kinase activity	10	9.81e-01	-4.34e-03	9.93e-01
GO:0060612 adipose tissue development	23	9.71e-01	-4.33e-03	9.90e-01
GO:0030522 intracellular receptor signaling pathway	18	9.76e-01	4.15e-03	9.92e-01
GO:0120020 cholesterol transfer activity	12	9.81e-01	3.97e-03	9.93e-01
GO:0009617 response to bacterium	34	9.71e-01	3.60e-03	9.90e-01
GO:0007519 skeletal muscle tissue development	17	9.81e-01	-3.41e-03	9.93e-01
GO:0070534 protein K63-linked ubiquitination	31	9.74e-01	-3.35e-03	9.92e-01
GO:0031625 ubiquitin protein ligase binding	172	9.40e-01	-3.32e-03	9.72e-01
GO:0032991 protein-containing complex	207	9.36e-01	-3.22e-03	9.70e-01
GO:0043525 positive regulation of neuron apoptotic process	18	9.82e-01	3.16e-03	9.93e-01
GO:0019882 antigen processing and presentation	11	9.88e-01	2.69e-03	9.97e-01
GO:0035098 ESC/E(Z) complex	12	9.87e-01	-2.68e-03	9.97e-01
GO:0010575 positive regulation of vascular endothelial growth factor production	13	9.87e-01	-2.55e-03	9.97e-01
GO:0042147 retrograde transport, endosome to Golgi	50	9.78e-01	-2.27e-03	9.93e-01
GO:0098685 Schaffer collateral - CA1 synapse	44	9.82e-01	2.00e-03	9.93e-01
GO:0005938 cell cortex	75	9.81e-01	-1.60e-03	9.93e-01
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors	18	9.91e-01	-1.51e-03	9.98e-01
GO:0070628 proteasome binding	13	9.93e-01	1.34e-03	9.98e-01
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation	30	9.90e-01	-1.27e-03	9.98e-01
GO:0061608 nuclear import signal receptor activity	15	9.93e-01	-1.26e-03	9.98e-01
GO:0032154 cleavage furrow	28	9.91e-01	-1.25e-03	9.98e-01
GO:0048675 axon extension	15	9.93e-01	-1.23e-03	9.98e-01
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway	12	9.95e-01	1.01e-03	9.98e-01
GO:0030593 neutrophil chemotaxis	12	9.95e-01	-9.98e-04	9.98e-01
GO:0055085 transmembrane transport	85	9.90e-01	-7.85e-04	9.98e-01
GO:0046982 protein heterodimerization activity	131	9.88e-01	7.80e-04	9.97e-01
GO:0051209 release of sequestered calcium ion into cytosol	20	9.96e-01	-6.63e-04	9.98e-01
GO:0007173 epidermal growth factor receptor signaling pathway	39	9.95e-01	-5.32e-04	9.98e-01
GO:0009566 fertilization	12	9.98e-01	-4.81e-04	9.99e-01
GO:0042742 defense response to bacterium	28	9.97e-01	-3.48e-04	9.99e-01
GO:0042802 identical protein binding	660	9.91e-01	2.47e-04	9.98e-01
GO:0008168 methyltransferase activity	13	9.99e-01	-1.41e-04	9.99e-01
GO:0005681 spliceosomal complex	43	9.99e-01	-9.19e-05	9.99e-01

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Detailed Gene set reports

GO:0022625 cytosolic large ribosomal subunit

set	GO:0022625 cytosolic large ribosomal subunit
setSize	40
pANOVA	2.13e-21
s.dist	0.867
p.adjustANOVA	1.88e-18

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL5	6981
RPL7A	6974
RPL13	6968
RPL9	6958
RPL27A	6955
RPL3	6952
RPL26L1	6928
RPL37	6905
RPL11	6900
RPL29	6895
RPL35	6884
RPL7	6863
RPL27	6852
RPL34	6838
RPL18A	6835
RPL38	6814
RPL37A	6813
RPL15	6798
RPL14	6795
RPL32	6765

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL5	6981
RPL7A	6974
RPL13	6968
RPL9	6958
RPL27A	6955
RPL3	6952
RPL26L1	6928
RPL37	6905
RPL11	6900
RPL29	6895
RPL35	6884
RPL7	6863
RPL27	6852
RPL34	6838
RPL18A	6835
RPL38	6814
RPL37A	6813
RPL15	6798
RPL14	6795
RPL32	6765
RPL8	6743
RPL31	6741
RPL30	6715
RPL23A	6703
RPL10A	6665
RPL35A	6584
RPL21	6523
RPL7L1	6451
RPL36	6310
RPLP0	6293
RPLP2	6214
RPL23	6126
RPL19	6110
RPL12	5939
RPL24	5853
RPL6	5129
RPLP1	3782
RPL4	1530
RPL3L	1085
ZCCHC17	-2993

---

GO:0002181 cytoplasmic translation

set	GO:0002181 cytoplasmic translation
setSize	27
pANOVA	1.25e-11
s.dist	0.753
p.adjustANOVA	4.41e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL9	6958
RPL26L1	6928
RPL29	6895
RPS23	6877
RPL18A	6835
RPS14	6820
RPL38	6814
RPL15	6798
RPL8	6743
RPL31	6741
RPS6	6701
RPL10A	6665
RPL35A	6584
RPL36	6310
RPLP0	6293
RPL22L1	6253
DRG2	6224
RPL24	5853
RPL22	5635
RWDD1	5481

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All member genes

GeneID	Gene Rank
RPL9	6958
RPL26L1	6928
RPL29	6895
RPS23	6877
RPL18A	6835
RPS14	6820
RPL38	6814
RPL15	6798
RPL8	6743
RPL31	6741
RPS6	6701
RPL10A	6665
RPL35A	6584
RPL36	6310
RPLP0	6293
RPL22L1	6253
DRG2	6224
RPL24	5853
RPL22	5635
RWDD1	5481
RPL6	5129
RPLP1	3782
RPS28	3093
RPS26	1528
ZC3H15	1257
RPS29	-1505
SARS1	-1920

---

GO:0045116 protein neddylation

set	GO:0045116 protein neddylation
setSize	10
pANOVA	5.6e-05
s.dist	0.736
p.adjustANOVA	0.00241

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NEDD8	6696
UBE2F	6537
UBA3	6402
DCUN1D5	5327
RBX1	5154
DCUN1D4	5147
DCUN1D2	5055
NAE1	4412
RNF7	3741
DCUN1D3	2882

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All member genes

GeneID	Gene Rank
NEDD8	6696
UBE2F	6537
UBA3	6402
DCUN1D5	5327
RBX1	5154
DCUN1D4	5147
DCUN1D2	5055
NAE1	4412
RNF7	3741
DCUN1D3	2882

---

GO:0022627 cytosolic small ribosomal subunit

set	GO:0022627 cytosolic small ribosomal subunit
setSize	25
pANOVA	2.7e-10
s.dist	0.729
p.adjustANOVA	5.13e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS2	7004
RPS15A	6997
RPS3A	6996
RPS12	6989
RPS4Y1	6972
RPS7	6944
RPS3	6940
RPS24	6906
RPS23	6877
RPS16	6821
RPS14	6820
RPS20	6787
RPS15	6779
RPS6	6701
RPS8	6644
RPS21	6411
RPS11	5695
RPS13	5580
RPS10	4070
EIF2A	3487

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS2	7004
RPS15A	6997
RPS3A	6996
RPS12	6989
RPS4Y1	6972
RPS7	6944
RPS3	6940
RPS24	6906
RPS23	6877
RPS16	6821
RPS14	6820
RPS20	6787
RPS15	6779
RPS6	6701
RPS8	6644
RPS21	6411
RPS11	5695
RPS13	5580
RPS10	4070
EIF2A	3487
RPS28	3093
RPS27L	2727
RPS26	1528
RPS29	-1505
LARP4	-7135

---

GO:0035145 exon-exon junction complex

set	GO:0035145 exon-exon junction complex
setSize	10
pANOVA	0.000112
s.dist	-0.705
p.adjustANOVA	0.00395

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UPF1	-7106
SRSF1	-7104
UPF2	-6633
SMG6	-6544
CASC3	-6527
THRAP3	-5941
TDRD3	-5742
PNN	-5731
UPF3B	-1969
UPF3A	2356

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UPF1	-7106
SRSF1	-7104
UPF2	-6633
SMG6	-6544
CASC3	-6527
THRAP3	-5941
TDRD3	-5742
PNN	-5731
UPF3B	-1969
UPF3A	2356

---

GO:0051393 alpha-actinin binding

set	GO:0051393 alpha-actinin binding
setSize	10
pANOVA	0.000129
s.dist	-0.699
p.adjustANOVA	0.00446

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ZYX	-7131
VCL	-7129
CACNA1C	-6963
PDLIM3	-6415
RARA	-5931
SYNPO2	-5756
DAG1	-5428
MAGI1	-4601
CSRP1	-999
CACNA1D	-143

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ZYX	-7131
VCL	-7129
CACNA1C	-6963
PDLIM3	-6415
RARA	-5931
SYNPO2	-5756
DAG1	-5428
MAGI1	-4601
CSRP1	-999
CACNA1D	-143

---

GO:0048041 focal adhesion assembly

set	GO:0048041 focal adhesion assembly
setSize	14
pANOVA	2.52e-05
s.dist	-0.65
p.adjustANOVA	0.00122

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FN1	-7081
PTPRK	-6856
PIP5K1A	-6594
FERMT2	-6478
CDH11	-6078
PEAK1	-6005
RCC2	-5737
CORO2B	-5634
THY1	-5503
BCR	-5314
BCL2	-5300
WHAMM	-3633
SRC	-2616
ARHGAP6	7006

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FN1	-7081
PTPRK	-6856
PIP5K1A	-6594
FERMT2	-6478
CDH11	-6078
PEAK1	-6005
RCC2	-5737
CORO2B	-5634
THY1	-5503
BCR	-5314
BCL2	-5300
WHAMM	-3633
SRC	-2616
ARHGAP6	7006

---

GO:0036121 double-stranded DNA helicase activity

set	GO:0036121 double-stranded DNA helicase activity
setSize	11
pANOVA	0.000305
s.dist	-0.629
p.adjustANOVA	0.00826

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	-7130
UPF1	-7106
CHD1	-6790
BLM	-6499
MCM3	-6483
MCM9	-5919
CHD7	-5793
IGHMBP2	-5263
ERCC3	-2546
MCM5	-891
MCM8	4366

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	-7130
UPF1	-7106
CHD1	-6790
BLM	-6499
MCM3	-6483
MCM9	-5919
CHD7	-5793
IGHMBP2	-5263
ERCC3	-2546
MCM5	-891
MCM8	4366

---

GO:0003735 structural constituent of ribosome

set	GO:0003735 structural constituent of ribosome
setSize	118
pANOVA	6.41e-32
s.dist	0.626
p.adjustANOVA	1.13e-28

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS2	7004
RPS15A	6997
RPS3A	6996
RPS12	6989
RPL5	6981
RPS4Y1	6972
RPL13	6968
RPL9	6958
RPL27A	6955
RPL3	6952
RPS7	6944
RPS3	6940
RPL26L1	6928
RPS24	6906
RPL37	6905
RPL11	6900
RPL29	6895
RPL35	6884
RPS23	6877
RPL7	6863

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS2	7004
RPS15A	6997
RPS3A	6996
RPS12	6989
RPL5	6981
RPS4Y1	6972
RPL13	6968
RPL9	6958
RPL27A	6955
RPL3	6952
RPS7	6944
RPS3	6940
RPL26L1	6928
RPS24	6906
RPL37	6905
RPL11	6900
RPL29	6895
RPL35	6884
RPS23	6877
RPL7	6863
RPL27	6852
RPL34	6838
RPL18A	6835
RPS16	6821
RPS14	6820
RPL38	6814
RPL37A	6813
RPL15	6798
RPL14	6795
RPS20	6787
RPS15	6779
RPL32	6765
RPS27A	6757
RPL8	6743
RPL31	6741
RPL30	6715
RPL23A	6703
RPS6	6701
RPL10A	6665
RPS8	6644
MRPL21	6595
RPL35A	6584
MRPS34	6539
RPL21	6523
RPL7L1	6451
MRPS18A	6441
MRPS17	6437
RPS21	6411
RPL36	6310
MRPL28	6301
RPLP0	6293
RPL22L1	6253
RPLP2	6214
RPL23	6126
RPL19	6110
MRPL35	6081
SRBD1	6039
RPS17	5997
RPL12	5939
MRPS31	5902
RPL24	5853
RPS11	5695
MRPL51	5667
RPL22	5635
RPS13	5580
DAP3	5453
MRPS6	5435
MRPL14	5379
MRPS18C	5234
RPL6	5129
MRPL32	5106
MRPS9	5072
MRPS23	5058
MRPL13	4793
MRPS22	4520
MRPL23	4383
RPS10	4070
MRPL18	3895
MRPL47	3838
MRPS25	3795
RPLP1	3782
MRPS21	3740
UBA52	3737
MRPS35	3692
MRPS16	3617
MRPL24	3223
RPS28	3093
RPS27L	2727
MRPL41	2668
MRPL37	2589
MRPS5	2412
MRPL27	2336
MRPL20	2324
MRPL15	2238
MRPL16	2152
MRPL22	1907
RPL4	1530
RPS26	1528
MRPL2	1128
MRPL3	1111
RPL3L	1085
MRPS12	944
DDA1	854
MRPL19	751
MRPS10	697
RPS29	-1505
MRPS30	-2525
MRPL10	-2566
MRPS7	-2681
MRPS11	-2804
MRPS15	-3083
MRPL36	-3661
MRPL49	-3734
MRPL46	-4131
MRPS2	-4292
MRPL12	-4330
MRPS14	-4673
MRPL17	-5049

---

GO:0032585 multivesicular body membrane

set	GO:0032585 multivesicular body membrane
setSize	12
pANOVA	0.000299
s.dist	0.603
p.adjustANOVA	0.00824

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CHMP4C	6857
SLC9A8	6552
CHMP1B	6462
CHMP2B	6066
SORL1	5328
CHMP3	5016
RAB27A	4661
CHMP5	3994
CHMP7	3987
CD63	3908
TMEM9	2732
CHMP2A	-5259

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CHMP4C	6857
SLC9A8	6552
CHMP1B	6462
CHMP2B	6066
SORL1	5328
CHMP3	5016
RAB27A	4661
CHMP5	3994
CHMP7	3987
CD63	3908
TMEM9	2732
CHMP2A	-5259

---

GO:0006337 nucleosome disassembly

set	GO:0006337 nucleosome disassembly
setSize	10
pANOVA	0.000972
s.dist	-0.602
p.adjustANOVA	0.0201

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SMARCA4	-6512
SMARCC1	-6143
ATAD2B	-5452
ARID2	-4838
SMARCD1	-4024
ATAD2	-3940
SMARCE1	-3678
SSRP1	-3675
SMARCB1	-3306
SMARCD2	-2062

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SMARCA4	-6512
SMARCC1	-6143
ATAD2B	-5452
ARID2	-4838
SMARCD1	-4024
ATAD2	-3940
SMARCE1	-3678
SSRP1	-3675
SMARCB1	-3306
SMARCD2	-2062

---

GO:0030992 intraciliary transport particle B

set	GO:0030992 intraciliary transport particle B
setSize	15
pANOVA	9.99e-05
s.dist	0.58
p.adjustANOVA	0.00367

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IFT52	6698
TRIM59	6643
IFT80	6095
IFT27	6034
IFT20	5944
HSPB11	5788
IFT57	5261
IFT81	4902
TRAF3IP1	4676
IFT22	3393
IFT74	2038
IFT88	1722
IFT172	1649
IFT46	1256
UBXN10	-1647

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IFT52	6698
TRIM59	6643
IFT80	6095
IFT27	6034
IFT20	5944
HSPB11	5788
IFT57	5261
IFT81	4902
TRAF3IP1	4676
IFT22	3393
IFT74	2038
IFT88	1722
IFT172	1649
IFT46	1256
UBXN10	-1647

---

GO:0000380 alternative mRNA splicing, via spliceosome

set	GO:0000380 alternative mRNA splicing, via spliceosome
setSize	16
pANOVA	8.9e-05
s.dist	-0.566
p.adjustANOVA	0.00341

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SRSF1	-7104
CDK13	-6959
HNRNPM	-6733
SRSF6	-6690
SFPQ	-6585
HNRNPU	-6400
HNRNPUL1	-6300
DDX17	-5565
SLU7	-4860
CELF2	-4718
PUF60	-4404
STRAP	-3059
RBM17	-2767
DDX5	-489
SFSWAP	2323
RSRC1	4677

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SRSF1	-7104
CDK13	-6959
HNRNPM	-6733
SRSF6	-6690
SFPQ	-6585
HNRNPU	-6400
HNRNPUL1	-6300
DDX17	-5565
SLU7	-4860
CELF2	-4718
PUF60	-4404
STRAP	-3059
RBM17	-2767
DDX5	-489
SFSWAP	2323
RSRC1	4677

---

GO:0140658 ATP-dependent chromatin remodeler activity

set	GO:0140658 ATP-dependent chromatin remodeler activity
setSize	11
pANOVA	0.00149
s.dist	-0.553
p.adjustANOVA	0.0257

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CHD6	-7032
CHD4	-6813
CHD1	-6790
RAD54L2	-6117
CHD7	-5793
CHD1L	-5477
CHD2	-4053
ERCC6	-3915
INO80	-3342
CHD5	960
SMARCAD1	4214

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CHD6	-7032
CHD4	-6813
CHD1	-6790
RAD54L2	-6117
CHD7	-5793
CHD1L	-5477
CHD2	-4053
ERCC6	-3915
INO80	-3342
CHD5	960
SMARCAD1	4214

---

GO:0060395 SMAD protein signal transduction

set	GO:0060395 SMAD protein signal transduction
setSize	14
pANOVA	0.000381
s.dist	-0.548
p.adjustANOVA	0.00974

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SMAD3	-7180
ZMIZ1	-6998
RBPMS	-6930
SMAD5	-6798
SMAD6	-6114
SMAD7B	-5638
HIPK2	-5471
FOS	-5375
WWTR1	-4233
SMAD1	-3621
JUN	-800
SMAD2	166
SMAD9	329
RUNX2	2960

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SMAD3	-7180
ZMIZ1	-6998
RBPMS	-6930
SMAD5	-6798
SMAD6	-6114
SMAD7B	-5638
HIPK2	-5471
FOS	-5375
WWTR1	-4233
SMAD1	-3621
JUN	-800
SMAD2	166
SMAD9	329
RUNX2	2960

---

GO:0042073 intraciliary transport

set	GO:0042073 intraciliary transport
setSize	16
pANOVA	0.000165
s.dist	0.544
p.adjustANOVA	0.00548

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IFT52	6698
TUB	6269
IFT27	6034
IFT20	5944
HSPB11	5788
IFT57	5261
NME7	5239
IFT81	4902
TRAF3IP1	4676
IFT122	4646
LCA5	3383
LCA5L	2298
IFT88	1722
IFT172	1649
IFT46	1256
KIF3B	-5390

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IFT52	6698
TUB	6269
IFT27	6034
IFT20	5944
HSPB11	5788
IFT57	5261
NME7	5239
IFT81	4902
TRAF3IP1	4676
IFT122	4646
LCA5	3383
LCA5L	2298
IFT88	1722
IFT172	1649
IFT46	1256
KIF3B	-5390

---

GO:0003148 outflow tract septum morphogenesis

set	GO:0003148 outflow tract septum morphogenesis
setSize	12
pANOVA	0.00133
s.dist	-0.535
p.adjustANOVA	0.0237

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TBX2	-6828
BMPR2	-6523
SMAD6	-6114
LRP2	-5940
RARA	-5931
NRP2	-5564
PARVA	-5312
BMPR1A	-4735
ISL1	-3970
ZFPM2	-2785
GATA6	535
SEMA3C	6556

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TBX2	-6828
BMPR2	-6523
SMAD6	-6114
LRP2	-5940
RARA	-5931
NRP2	-5564
PARVA	-5312
BMPR1A	-4735
ISL1	-3970
ZFPM2	-2785
GATA6	535
SEMA3C	6556

---

GO:0006120 mitochondrial electron transport, NADH to ubiquinone

set	GO:0006120 mitochondrial electron transport, NADH to ubiquinone
setSize	19
pANOVA	7.27e-05
s.dist	0.526
p.adjustANOVA	0.00298

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NDUFB9	6101
NDUFA8	5831
NDUFV2	5783
NDUFAF1	5608
ND5	5493
ND2	5483
NDUFS3	5204
NDUFA10	5120
NDUFB6	4884
DNAJC15	4552
DLD	4510
NDUFS1	3984
NDUFC2	3655
NDUFB8	3312
NDUFS8	3196
NDUFS6	1820
NDUFS2	849
NDUFS7	-1986
NDUFV1	-4188

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All member genes

GeneID	Gene Rank
NDUFB9	6101
NDUFA8	5831
NDUFV2	5783
NDUFAF1	5608
ND5	5493
ND2	5483
NDUFS3	5204
NDUFA10	5120
NDUFB6	4884
DNAJC15	4552
DLD	4510
NDUFS1	3984
NDUFC2	3655
NDUFB8	3312
NDUFS8	3196
NDUFS6	1820
NDUFS2	849
NDUFS7	-1986
NDUFV1	-4188

---

GO:0000793 condensed chromosome

set	GO:0000793 condensed chromosome
setSize	13
pANOVA	0.00103
s.dist	-0.526
p.adjustANOVA	0.0203

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TOP2A	-7075
BAZ1B	-6992
RIF1	-6801
SMC2	-6369
CTCF	-6264
FANCD2	-5436
CDK2	-3764
SMARCA5	-3752
TOP3B	-2645
NCAPG	-1536
NCAPD2	-973
LIG4	958
HMGB2	1018

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TOP2A	-7075
BAZ1B	-6992
RIF1	-6801
SMC2	-6369
CTCF	-6264
FANCD2	-5436
CDK2	-3764
SMARCA5	-3752
TOP3B	-2645
NCAPG	-1536
NCAPD2	-973
LIG4	958
HMGB2	1018

---

GO:0070411 I-SMAD binding

set	GO:0070411 I-SMAD binding
setSize	11
pANOVA	0.00262
s.dist	-0.524
p.adjustANOVA	0.0392

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SMAD3	-7180
AXIN2	-7009
SMAD5	-6798
CTNNB1	-6479
SMAD6	-6114
SMAD7B	-5638
AXIN1	-5240
SMAD1	-3621
SMAD2	166
SMAD9	329
SMURF1	5719

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SMAD3	-7180
AXIN2	-7009
SMAD5	-6798
CTNNB1	-6479
SMAD6	-6114
SMAD7B	-5638
AXIN1	-5240
SMAD1	-3621
SMAD2	166
SMAD9	329
SMURF1	5719

---

GO:0006412 translation

set	GO:0006412 translation
setSize	96
pANOVA	1.18e-18
s.dist	0.521
p.adjustANOVA	6.94e-16

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS2	7004
RPS15A	6997
RPS3A	6996
RPL5	6981
RPS4Y1	6972
RPL13	6968
RPL27A	6955
RPL3	6952
RPS7	6944
RPS3	6940
RPL26L1	6928
RPS24	6906
RPL37	6905
RPL11	6900
RPL35	6884
RPS23	6877
RPL27	6852
RPL34	6838
RPS16	6821
RPS14	6820

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS2	7004
RPS15A	6997
RPS3A	6996
RPL5	6981
RPS4Y1	6972
RPL13	6968
RPL27A	6955
RPL3	6952
RPS7	6944
RPS3	6940
RPL26L1	6928
RPS24	6906
RPL37	6905
RPL11	6900
RPL35	6884
RPS23	6877
RPL27	6852
RPL34	6838
RPS16	6821
RPS14	6820
RPL37A	6813
RPL14	6795
RPS20	6787
RPS15	6779
RPL32	6765
RPS27A	6757
RPL23A	6703
RPS8	6644
GSPT2	6593
RPL35A	6584
RPL21	6523
MRPS18A	6441
MRPS17	6437
RPS21	6411
RPL22L1	6253
RPL23	6126
RPL19	6110
MRPL35	6081
SRBD1	6039
RPS17	5997
RPL12	5939
RPS11	5695
MRPL51	5667
RPL22	5635
RPS13	5580
MRPS6	5435
MRPL14	5379
MRPS18C	5234
GUF1	5158
MRPL32	5106
MRPS9	5072
MRPS23	5058
MRPL13	4793
EIF2AK2	4271
C2H6orf52	4147
MRPL18	3895
MRPL47	3838
MRPS21	3740
UBA52	3737
MRPS16	3617
MRPL24	3223
RPS27L	2727
MRPL41	2668
MRPL37	2589
MRPS5	2412
MRPL27	2336
MRPL20	2324
MRPL15	2238
MRPL16	2152
MRPL22	1907
RPL4	1530
MRPL2	1128
MRPL3	1111
RPL3L	1085
MRPS12	944
TRNAU1AP	923
DDA1	854
MRPL19	751
MRPS10	697
CPEB3	525
RPS29	-1505
MRPL33	-1678
HBS1L	-1795
MRPS30	-2525
MRPL10	-2566
MRPS7	-2681
MRPS11	-2804
MRPS15	-3083
MRPL36	-3661
MRPL49	-3734
MRPS2	-4292
MRPL12	-4330
MRPS14	-4673
MRPL17	-5049
EIF4ENIF1	-5204
CPEB4	-5340

---

GO:1902774 late endosome to lysosome transport

set	GO:1902774 late endosome to lysosome transport
setSize	10
pANOVA	0.00443
s.dist	0.52
p.adjustANOVA	0.0569

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CHMP4C	6857
CHMP1B	6462
CHMP2B	6066
VPS39	5899
CHMP3	5016
CHMP5	3994
CHMP7	3987
VPS41	3328
C9orf72	-326
CHMP2A	-5259

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CHMP4C	6857
CHMP1B	6462
CHMP2B	6066
VPS39	5899
CHMP3	5016
CHMP5	3994
CHMP7	3987
VPS41	3328
C9orf72	-326
CHMP2A	-5259

---

GO:0070182 DNA polymerase binding

set	GO:0070182 DNA polymerase binding
setSize	13
pANOVA	0.00119
s.dist	-0.519
p.adjustANOVA	0.0221

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FANCI	-6837
SMG6	-6544
SMARCA4	-6512
NAT10	-6102
FANCD2	-5436
LONP1	-5372
NABP2	-5087
RTEL1	-4943
HSP90AA1	-4522
NHEJ1	-2598
PTGES3	-2361
POLG2	657
PCNA	6630

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FANCI	-6837
SMG6	-6544
SMARCA4	-6512
NAT10	-6102
FANCD2	-5436
LONP1	-5372
NABP2	-5087
RTEL1	-4943
HSP90AA1	-4522
NHEJ1	-2598
PTGES3	-2361
POLG2	657
PCNA	6630

---

GO:0004602 glutathione peroxidase activity

set	GO:0004602 glutathione peroxidase activity
setSize	12
pANOVA	0.00259
s.dist	0.502
p.adjustANOVA	0.0391

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GPX7	6669
GPX4	6138
GPX3	5967
MGST1	5698
MGST3	5617
CLIC2	5479
GSTK1	5252
CP	4511
PRDX6	3102
GPX8	-1363
GPX1	-1407
PTGES	-3933

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GPX7	6669
GPX4	6138
GPX3	5967
MGST1	5698
MGST3	5617
CLIC2	5479
GSTK1	5252
CP	4511
PRDX6	3102
GPX8	-1363
GPX1	-1407
PTGES	-3933

---

GO:0008593 regulation of Notch signaling pathway

set	GO:0008593 regulation of Notch signaling pathway
setSize	10
pANOVA	0.00667
s.dist	0.495
p.adjustANOVA	0.0736

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LLGL2	6673
POFUT1	6516
LFNG	5515
RFNG	5491
GALNT11	5236
LLGL1	4456
TSPEAR	4158
ADAM10	2577
PRAG1	-3152
POSTN	-3173

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LLGL2	6673
POFUT1	6516
LFNG	5515
RFNG	5491
GALNT11	5236
LLGL1	4456
TSPEAR	4158
ADAM10	2577
PRAG1	-3152
POSTN	-3173

---

GO:0032968 positive regulation of transcription elongation by RNA polymerase II

set	GO:0032968 positive regulation of transcription elongation by RNA polymerase II
setSize	15
pANOVA	0.00103
s.dist	-0.489
p.adjustANOVA	0.0203

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LEO1	-7078
CDK13	-6959
SUPT6H	-6662
CTNNB1	-6479
ZMYND8	-6306
CDK12	-6260
PWWP2B	-5661
ELL	-4383
CDC73	-3259
PWWP2A	-2487
ELL2	-2456
CCNT1	-2398
OCLN	-1372
CDK9	2436
EAPP	5932

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LEO1	-7078
CDK13	-6959
SUPT6H	-6662
CTNNB1	-6479
ZMYND8	-6306
CDK12	-6260
PWWP2B	-5661
ELL	-4383
CDC73	-3259
PWWP2A	-2487
ELL2	-2456
CCNT1	-2398
OCLN	-1372
CDK9	2436
EAPP	5932

---

GO:0034727 piecemeal microautophagy of the nucleus

set	GO:0034727 piecemeal microautophagy of the nucleus
setSize	13
pANOVA	0.00235
s.dist	0.487
p.adjustANOVA	0.0367

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SNX7	6339
ATG5	6204
ATG4C	5988
RB1CC1	5745
ATG4A	5315
ATG13	5093
ATG7	4815
ATG4B	4482
ULK2	3739
SNX30	2422
ULK1	517
ULK3	50
ATG9A	-6885

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SNX7	6339
ATG5	6204
ATG4C	5988
RB1CC1	5745
ATG4A	5315
ATG13	5093
ATG7	4815
ATG4B	4482
ULK2	3739
SNX30	2422
ULK1	517
ULK3	50
ATG9A	-6885

---

GO:0070577 lysine-acetylated histone binding

set	GO:0070577 lysine-acetylated histone binding
setSize	16
pANOVA	0.000793
s.dist	-0.485
p.adjustANOVA	0.0175

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MLLT1	-7114
BRD2	-6632
DPF2	-6525
PHIP	-6524
ZMYND8	-6306
BRPF3	-6054
ATAD2B	-5452
BRD3	-5053
ZZEF1	-4486
ZZZ3	-4137
KMT2A	-3533
PSME4	-2971
MLLT3	-279
BRD9	2813
TRIM24	2894
BRD7	2962

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MLLT1	-7114
BRD2	-6632
DPF2	-6525
PHIP	-6524
ZMYND8	-6306
BRPF3	-6054
ATAD2B	-5452
BRD3	-5053
ZZEF1	-4486
ZZZ3	-4137
KMT2A	-3533
PSME4	-2971
MLLT3	-279
BRD9	2813
TRIM24	2894
BRD7	2962

---

GO:0061749 forked DNA-dependent helicase activity

set	GO:0061749 forked DNA-dependent helicase activity
setSize	10
pANOVA	0.008
s.dist	-0.484
p.adjustANOVA	0.0802

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	-7130
CHD1	-6790
BLM	-6499
MCM3	-6483
MCM9	-5919
CHD7	-5793
ERCC3	-2546
MCM5	-891
WRN	2433
MCM8	4366

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	-7130
CHD1	-6790
BLM	-6499
MCM3	-6483
MCM9	-5919
CHD7	-5793
ERCC3	-2546
MCM5	-891
WRN	2433
MCM8	4366

---

GO:0009653 anatomical structure morphogenesis

set	GO:0009653 anatomical structure morphogenesis
setSize	22
pANOVA	9.11e-05
s.dist	-0.482
p.adjustANOVA	0.00342

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SMAD3	-7180
CSPG4	-7001
ATOH8	-6978
ANKRD11	-6855
SMAD5	-6798
FBN2	-6797
SMAD6	-6114
FBN1	-6071
ACVR1B	-5898
SMAD7B	-5638
FREM2	-5557
SMAD1	-3621
ACVR1C	-2766
FOXD1	-2312
ONECUT1	-2047
ONECUT2	-1640
PAX7	-691
PITX1	-418
SMAD2	166
SMAD9	329

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SMAD3	-7180
CSPG4	-7001
ATOH8	-6978
ANKRD11	-6855
SMAD5	-6798
FBN2	-6797
SMAD6	-6114
FBN1	-6071
ACVR1B	-5898
SMAD7B	-5638
FREM2	-5557
SMAD1	-3621
ACVR1C	-2766
FOXD1	-2312
ONECUT1	-2047
ONECUT2	-1640
PAX7	-691
PITX1	-418
SMAD2	166
SMAD9	329
FOXL1	2469
PITX2	4300

---

GO:0046849 bone remodeling

set	GO:0046849 bone remodeling
setSize	10
pANOVA	0.0086
s.dist	-0.48
p.adjustANOVA	0.0843

Top enriched genes

Top 20 genes

GeneID	Gene Rank
EPHA2	-7046
NOTCH2	-6641
HTR1B	-5770
P3H4	-5170
MITF	-4405
SPP2	-4043
LRP5	-2833
EFNA2	-1404
LGR4	-1270
RASSF2	3648

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
EPHA2	-7046
NOTCH2	-6641
HTR1B	-5770
P3H4	-5170
MITF	-4405
SPP2	-4043
LRP5	-2833
EFNA2	-1404
LGR4	-1270
RASSF2	3648

---

GO:0001725 stress fiber

set	GO:0001725 stress fiber
setSize	42
pANOVA	8.09e-08
s.dist	-0.478
p.adjustANOVA	7.51e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ACTN1	-7170
ZYX	-7131
VCL	-7129
MYH10	-7107
FHL3	-7094
PDLIM1	-6989
PDLIM7	-6973
MYH9	-6896
PALLD	-6834
MYL9	-6817
SEPTIN9	-6811
SYNPO	-6772
LPP	-6743
FERMT2	-6478
PDLIM3	-6415
DCTN4	-6378
CALD1	-6227
SEPTIN7	-5887
PXN	-5780
SYNPO2	-5756

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ACTN1	-7170
ZYX	-7131
VCL	-7129
MYH10	-7107
FHL3	-7094
PDLIM1	-6989
PDLIM7	-6973
MYH9	-6896
PALLD	-6834
MYL9	-6817
SEPTIN9	-6811
SYNPO	-6772
LPP	-6743
FERMT2	-6478
PDLIM3	-6415
DCTN4	-6378
CALD1	-6227
SEPTIN7	-5887
PXN	-5780
SYNPO2	-5756
LIMA1	-5695
MYLK	-5604
LIMCH1	-5072
BLOC1S6	-4837
CORO1B	-4746
PDLIM5	-4376
CNN2	-4201
ABLIM1	-2293
PPP1R12A	-2111
AFAP1	-1779
SEPTIN11	-1627
CSRP1	-999
XIRP1	-914
EVL	449
TPM4	464
PDLIM4	961
FHOD1	3488
FBLIM1	3688
DAAM1	4394
MST1R	4828
MICALL2	6386
NEBL	6999

---

GO:0060045 positive regulation of cardiac muscle cell proliferation

set	GO:0060045 positive regulation of cardiac muscle cell proliferation
setSize	13
pANOVA	0.00303
s.dist	-0.475
p.adjustANOVA	0.0427

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TBX2	-6828
YAP1	-6602
NOTCH1	-6473
PIM1	-5828
GLI1	-5265
HEY2	-4956
BMPR1A	-4735
RBPJ	-4647
ERBB4	-3333
ZFPM2	-2785
GATA6	535
MAPK14	1886
FGFR1	4079

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TBX2	-6828
YAP1	-6602
NOTCH1	-6473
PIM1	-5828
GLI1	-5265
HEY2	-4956
BMPR1A	-4735
RBPJ	-4647
ERBB4	-3333
ZFPM2	-2785
GATA6	535
MAPK14	1886
FGFR1	4079

---

GO:0070034 telomerase RNA binding

set	GO:0070034 telomerase RNA binding
setSize	12
pANOVA	0.00452
s.dist	-0.473
p.adjustANOVA	0.057

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SMG7	-6993
SMG5	-6822
SMG6	-6544
HNRNPU	-6400
EXOSC10	-4093
DHX36	-3888
GAR1	-3789
XRN1	-3749
PINX1	-3742
NAF1	-1327
DKC1	-237
PARN	6220

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SMG7	-6993
SMG5	-6822
SMG6	-6544
HNRNPU	-6400
EXOSC10	-4093
DHX36	-3888
GAR1	-3789
XRN1	-3749
PINX1	-3742
NAF1	-1327
DKC1	-237
PARN	6220

---

GO:0060379 cardiac muscle cell myoblast differentiation

set	GO:0060379 cardiac muscle cell myoblast differentiation
setSize	10
pANOVA	0.01
s.dist	-0.47
p.adjustANOVA	0.09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SRF	-7145
MYOCD	-7080
TBX2	-6828
REST	-6679
NOTCH1	-6473
RBPJ	-4647
ISL1	-3970
TBXT	-2457
NRG1	4428
ITGB1	6602

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SRF	-7145
MYOCD	-7080
TBX2	-6828
REST	-6679
NOTCH1	-6473
RBPJ	-4647
ISL1	-3970
TBXT	-2457
NRG1	4428
ITGB1	6602

---

GO:0000245 spliceosomal complex assembly

set	GO:0000245 spliceosomal complex assembly
setSize	10
pANOVA	0.0101
s.dist	-0.47
p.adjustANOVA	0.09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SCAF11	-6013
PRPF19	-5723
USP39	-5570
ZRSR2	-4925
SF3A2	-4878
SRPK1	-4662
SF3B1	-4314
RBM10	-1141
SRPK2	-900
RSRP1	3910

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SCAF11	-6013
PRPF19	-5723
USP39	-5570
ZRSR2	-4925
SF3A2	-4878
SRPK1	-4662
SF3B1	-4314
RBM10	-1141
SRPK2	-900
RSRP1	3910

---

GO:1900181 negative regulation of protein localization to nucleus

set	GO:1900181 negative regulation of protein localization to nucleus
setSize	11
pANOVA	0.00714
s.dist	-0.468
p.adjustANOVA	0.0764

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SIN3A	-6794
MARK3	-6572
CTNNA1	-6416
MFHAS1	-6280
OTUD7B	-5959
MTOR	-5950
LZTS2	-5461
LATS1	-4481
LATS2	-2610
DCLK1	6060
YWHAZ	6930

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SIN3A	-6794
MARK3	-6572
CTNNA1	-6416
MFHAS1	-6280
OTUD7B	-5959
MTOR	-5950
LZTS2	-5461
LATS1	-4481
LATS2	-2610
DCLK1	6060
YWHAZ	6930

---

GO:0005840 ribosome

set	GO:0005840 ribosome
setSize	43
pANOVA	1.13e-07
s.dist	0.468
p.adjustANOVA	9.98e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SLC37A4	6986
RPS4Y1	6972
RPL11	6900
RPS23	6877
RPL27	6852
RPL34	6838
RPL32	6765
RPS27A	6757
RPL30	6715
FXR1	6616
RPS21	6411
RPL22L1	6253
MRPL35	6081
RACK1	6025
RPS17	5997
MRPS33	5816
PSMA6	5748
RPL22	5635
MRPS6	5435
MRPS18C	5234

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SLC37A4	6986
RPS4Y1	6972
RPL11	6900
RPS23	6877
RPL27	6852
RPL34	6838
RPL32	6765
RPS27A	6757
RPL30	6715
FXR1	6616
RPS21	6411
RPL22L1	6253
MRPL35	6081
RACK1	6025
RPS17	5997
MRPS33	5816
PSMA6	5748
RPL22	5635
MRPS6	5435
MRPS18C	5234
MRPS9	5072
MRPS23	5058
MRPL13	4793
MRPL18	3895
MRPS25	3795
RPLP1	3782
MRPS21	3740
UBA52	3737
MRPL24	3223
EEF2	3144
MRPL1	1771
MRPS12	944
DDA1	854
MRPL45	462
PTCD3	135
RPS29	-1505
MRPL33	-1678
MRPS7	-2681
MRPL46	-4131
HSPA14	-4544
GADD45GIP1	-4650
NUFIP2	-6343
EIF4G1	-7153

---

GO:0006641 triglyceride metabolic process

set	GO:0006641 triglyceride metabolic process
setSize	10
pANOVA	0.0106
s.dist	0.467
p.adjustANOVA	0.093

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SLC37A4	6986
CAV1	6926
CAT	6421
INSIG2	6223
INSIG1	5542
SEL1L	2039
LIPA	901
CETP	543
GK5	-104
LMF1	-3223

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SLC37A4	6986
CAV1	6926
CAT	6421
INSIG2	6223
INSIG1	5542
SEL1L	2039
LIPA	901
CETP	543
GK5	-104
LMF1	-3223

---

GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

set	GO:2001244 positive regulation of intrinsic apoptotic signaling pathway
setSize	11
pANOVA	0.00751
s.dist	0.465
p.adjustANOVA	0.078

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CAV1	6926
BID	6535
RACK1	6025
PLEKHF1	5339
SIAH1	5215
DFNA5	4686
FLCN	4560
SLC9A3R1	1611
BCLAF1	120
LCK	-832
PLAGL2	-4797

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CAV1	6926
BID	6535
RACK1	6025
PLEKHF1	5339
SIAH1	5215
DFNA5	4686
FLCN	4560
SLC9A3R1	1611
BCLAF1	120
LCK	-832
PLAGL2	-4797

---

GO:0016442 RISC complex

set	GO:0016442 RISC complex
setSize	11
pANOVA	0.00797
s.dist	-0.462
p.adjustANOVA	0.0802

Top enriched genes

Top 20 genes

GeneID	Gene Rank
XPO5	-6890
DDX6	-6424
DICER1	-5902
AGO2	-5476
AGO3	-5212
TNRC6A	-5081
TARBP2	-4072
DCP2	-2856
AGO4	-2264
LIMD1	945
EIF4E	6201

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
XPO5	-6890
DDX6	-6424
DICER1	-5902
AGO2	-5476
AGO3	-5212
TNRC6A	-5081
TARBP2	-4072
DCP2	-2856
AGO4	-2264
LIMD1	945
EIF4E	6201

---

GO:0045271 respiratory chain complex I

set	GO:0045271 respiratory chain complex I
setSize	31
pANOVA	9.1e-06
s.dist	0.461
p.adjustANOVA	0.000535

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NDUFA9	6265
NDUFB9	6101
NDUFB3	5875
NDUFS4	5849
NDUFA8	5831
NDUFV2	5783
ND5	5493
ND2	5483
NDUFS3	5204
NDUFA10	5120
NDUFB6	4884
NDUFA5	4559
NDUFB5	4490
NDUFA6	4277
NDUFA2	4252
NDUFAB1	3989
NDUFS1	3984
NDUFB10	3682
NDUFC2	3655
NDUFB8	3312

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NDUFA9	6265
NDUFB9	6101
NDUFB3	5875
NDUFS4	5849
NDUFA8	5831
NDUFV2	5783
ND5	5493
ND2	5483
NDUFS3	5204
NDUFA10	5120
NDUFB6	4884
NDUFA5	4559
NDUFB5	4490
NDUFA6	4277
NDUFA2	4252
NDUFAB1	3989
NDUFS1	3984
NDUFB10	3682
NDUFC2	3655
NDUFB8	3312
NDUFA12	3289
NDUFS8	3196
NDUFV3	2801
NDUFS5	1869
NDUFS6	1820
NDUFS2	849
NDUFA13	-38
NDUFB2	-694
NDUFS7	-1986
NDUFV1	-4188
NDUFB4	-6513

---

GO:0043296 apical junction complex

set	GO:0043296 apical junction complex
setSize	10
pANOVA	0.0118
s.dist	-0.46
p.adjustANOVA	0.101

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PARD3B	-6780
FRMD6	-6156
PKN2	-6148
SHROOM2	-5812
PARD3	-5101
FBF1	-4638
SAPCD2	-3035
CCDC85C	-1374
NECTIN3	1441
SHROOM3	4078

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PARD3B	-6780
FRMD6	-6156
PKN2	-6148
SHROOM2	-5812
PARD3	-5101
FBF1	-4638
SAPCD2	-3035
CCDC85C	-1374
NECTIN3	1441
SHROOM3	4078

---

GO:0030016 myofibril

set	GO:0030016 myofibril
setSize	14
pANOVA	0.00293
s.dist	-0.459
p.adjustANOVA	0.042

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LMOD1	-7157
MYH15	-7079
MYL9	-6817
CALD1	-6227
SCO2	-6051
TMOD2	-5220
TMOD4	-4545
COL6A1	-3820
TWF2	-3012
MYH1B	-719
LMOD3	94
MYH11	687
TWF1	1186
TMOD3	1828

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LMOD1	-7157
MYH15	-7079
MYL9	-6817
CALD1	-6227
SCO2	-6051
TMOD2	-5220
TMOD4	-4545
COL6A1	-3820
TWF2	-3012
MYH1B	-719
LMOD3	94
MYH11	687
TWF1	1186
TMOD3	1828

---

GO:0004364 glutathione transferase activity

set	GO:0004364 glutathione transferase activity
setSize	10
pANOVA	0.0121
s.dist	0.458
p.adjustANOVA	0.103

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HPGDS	6965
GSTO2	6801
MGST1	5698
MGST3	5617
GSTK1	5252
GSTT1	4356
GSTM2	3228
GSTZ1	2500
PTGES	-3933
LANCL1	-4834

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HPGDS	6965
GSTO2	6801
MGST1	5698
MGST3	5617
GSTK1	5252
GSTT1	4356
GSTM2	3228
GSTZ1	2500
PTGES	-3933
LANCL1	-4834

---

GO:0030900 forebrain development

set	GO:0030900 forebrain development
setSize	20
pANOVA	0.000401
s.dist	-0.457
p.adjustANOVA	0.00997

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ARHGAP35	-7084
SETD2	-6951
NOTCH1	-6473
ATRX	-6406
PRKG1	-6179
NR2F2	-6041
DYNC2H1	-5961
LRP2	-5940
TOP2B	-5449
APP	-5122
NDST1	-4954
FRS2	-4927
HTRA2	-4719
E2F1	-3891
SRC	-2616
ALDH1A2	-1657
APAF1	-717
DCLK1	6060
TWSG1	6183
FYN	6244

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ARHGAP35	-7084
SETD2	-6951
NOTCH1	-6473
ATRX	-6406
PRKG1	-6179
NR2F2	-6041
DYNC2H1	-5961
LRP2	-5940
TOP2B	-5449
APP	-5122
NDST1	-4954
FRS2	-4927
HTRA2	-4719
E2F1	-3891
SRC	-2616
ALDH1A2	-1657
APAF1	-717
DCLK1	6060
TWSG1	6183
FYN	6244

---

GO:1990518 single-stranded 3’-5’ DNA helicase activity

set	GO:1990518 single-stranded 3’-5’ DNA helicase activity
setSize	11
pANOVA	0.00882
s.dist	-0.456
p.adjustANOVA	0.0855

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	-7130
CHD1	-6790
BLM	-6499
MCM3	-6483
MCM9	-5919
CHD7	-5793
MCM6	-4636
ERCC3	-2546
MCM5	-891
MCM8	4366
HELQ	5757

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	-7130
CHD1	-6790
BLM	-6499
MCM3	-6483
MCM9	-5919
CHD7	-5793
MCM6	-4636
ERCC3	-2546
MCM5	-891
MCM8	4366
HELQ	5757

---

GO:0031466 Cul5-RING ubiquitin ligase complex

set	GO:0031466 Cul5-RING ubiquitin ligase complex
setSize	11
pANOVA	0.00895
s.dist	0.455
p.adjustANOVA	0.0858

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TCEB1	6158
PCMTD1	6052
KLHDC1	5926
SOCS2	5208
RBX1	5154
ASB9	3803
RNF7	3741
SPSB3	3654
CUL5	834
ELOB	-1805
ARIH2	-4143

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TCEB1	6158
PCMTD1	6052
KLHDC1	5926
SOCS2	5208
RBX1	5154
ASB9	3803
RNF7	3741
SPSB3	3654
CUL5	834
ELOB	-1805
ARIH2	-4143

---

GO:0009888 tissue development

set	GO:0009888 tissue development
setSize	18
pANOVA	0.000836
s.dist	-0.455
p.adjustANOVA	0.0178

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NTN4	-7056
LAMC1	-6911
NTN3	-6861
LAMC2	-6555
ACVR1B	-5898
NTNG2	-5763
LAMA5	-5406
SMO	-5178
LAMA3	-4868
DHCR24	-4576
POSTN	-3173
ACVR1C	-2766
LAMB1	-2288
USH2A	97
GAA	1372
LAMA2	1473
LAMB3	1495
LAMB2	3212

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NTN4	-7056
LAMC1	-6911
NTN3	-6861
LAMC2	-6555
ACVR1B	-5898
NTNG2	-5763
LAMA5	-5406
SMO	-5178
LAMA3	-4868
DHCR24	-4576
POSTN	-3173
ACVR1C	-2766
LAMB1	-2288
USH2A	97
GAA	1372
LAMA2	1473
LAMB3	1495
LAMB2	3212

---

GO:0017056 structural constituent of nuclear pore

set	GO:0017056 structural constituent of nuclear pore
setSize	19
pANOVA	0.000652
s.dist	-0.452
p.adjustANOVA	0.0152

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TPR	-7109
NUP98	-7070
NUP205	-6984
NUP188	-6958
NUP214	-6637
NUP153	-6609
NUP160	-5882
NUP58	-5767
NUP155	-5173
NUP133	-4948
NUP35	-4640
NUP62	-4200
NDC1	-3370
NUP107	-2228
NUP54	322
NUP85	2379
NUP93	2628
NUP88	2846
NUTF2	6855

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TPR	-7109
NUP98	-7070
NUP205	-6984
NUP188	-6958
NUP214	-6637
NUP153	-6609
NUP160	-5882
NUP58	-5767
NUP155	-5173
NUP133	-4948
NUP35	-4640
NUP62	-4200
NDC1	-3370
NUP107	-2228
NUP54	322
NUP85	2379
NUP93	2628
NUP88	2846
NUTF2	6855

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.4.2 (2024-10-31)
## Platform: x86_64-pc-linux-gnu
## Running under: Ubuntu 24.04.1 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.12.0 
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.12.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Australia/Melbourne
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] stats4    stats     graphics  grDevices utils     datasets  methods  
## [8] base     
## 
## other attached packages:
##  [1] pkgload_1.4.0               GGally_2.2.1               
##  [3] ggplot2_3.5.1               gtools_3.9.5               
##  [5] tibble_3.2.1                echarts4r_0.4.5            
##  [7] UpSetR_1.4.0                beeswarm_0.4.0             
##  [9] kableExtra_1.4.0            eulerr_7.0.2               
## [11] mitch_1.19.2                MASS_7.3-61                
## [13] gplots_3.2.0                DESeq2_1.44.0              
## [15] SummarizedExperiment_1.34.0 Biobase_2.64.0             
## [17] MatrixGenerics_1.16.0       matrixStats_1.4.1          
## [19] GenomicRanges_1.56.1        GenomeInfoDb_1.40.1        
## [21] IRanges_2.38.1              S4Vectors_0.42.1           
## [23] BiocGenerics_0.50.0         reshape2_1.4.4             
## [25] dplyr_1.1.4                 zoo_1.8-12                 
## 
## loaded via a namespace (and not attached):
##  [1] tidyselect_1.2.1        viridisLite_0.4.2       farver_2.1.2           
##  [4] bitops_1.0-9            fastmap_1.2.0           promises_1.3.2         
##  [7] digest_0.6.37           mime_0.12               lifecycle_1.0.4        
## [10] polylabelr_0.3.0        magrittr_2.0.3          compiler_4.4.2         
## [13] rlang_1.1.4             sass_0.4.9              tools_4.4.2            
## [16] yaml_2.3.10             knitr_1.49              labeling_0.4.3         
## [19] S4Arrays_1.4.1          htmlwidgets_1.6.4       DelayedArray_0.30.1    
## [22] xml2_1.3.6              plyr_1.8.9              RColorBrewer_1.1-3     
## [25] abind_1.4-8             BiocParallel_1.38.0     KernSmooth_2.23-24     
## [28] withr_3.0.2             purrr_1.0.2             polyclip_1.10-7        
## [31] grid_4.4.2              caTools_1.18.3          xtable_1.8-4           
## [34] colorspace_2.1-1        scales_1.3.0            cli_3.6.3              
## [37] rmarkdown_2.29          crayon_1.5.3            generics_0.1.3         
## [40] rstudioapi_0.17.1       httr_1.4.7              cachem_1.1.0           
## [43] stringr_1.5.1           zlibbioc_1.50.0         parallel_4.4.2         
## [46] XVector_0.44.0          vctrs_0.6.5             Matrix_1.7-1           
## [49] jsonlite_1.8.9          systemfonts_1.1.0       locfit_1.5-9.10        
## [52] jquerylib_0.1.4         tidyr_1.3.1             glue_1.8.0             
## [55] ggstats_0.7.0           codetools_0.2-20        stringi_1.8.4          
## [58] gtable_0.3.6            later_1.4.1             UCSC.utils_1.0.0       
## [61] munsell_0.5.1           pillar_1.10.0           htmltools_0.5.8.1      
## [64] GenomeInfoDbData_1.2.12 R6_2.5.1                evaluate_1.0.1         
## [67] shiny_1.10.0            lattice_0.22-6          httpuv_1.6.15          
## [70] bslib_0.8.0             Rcpp_1.0.13-1           svglite_2.1.3          
## [73] gridExtra_2.3           SparseArray_1.4.8       xfun_0.49              
## [76] pkgconfig_2.0.3

END of report