Mitch Report

date generated: 2025-01-14

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch

	stat
5_8S_rRNA	-1.4177988
A4GALT	-1.9324721
AAAS	0.0304075
AACS	4.5704709
AADAC	1.0608890
AADAT	0.6671932

Here are some metrics about the input data profile:

Profiling data metrics

	Profile metrics
num_genesets	5133
num_genes_in_profile	14380
duplicated_genes_present	0
num_profile_genes_in_sets	9204
num_profile_genes_not_in_sets	5176

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets:

Gene set metrics

	Gene sets metrics
num_genesets	5133
num_genesets_excluded	3361
num_genesets_included	1772

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

set	setSize	pANOVA	s.dist	p.adjustANOVA
GO:0045943 positive regulation of transcription by RNA polymerase I	11	7.55e-07	0.861	5.35e-05
GO:0005049 nuclear export signal receptor activity	10	1.12e-05	0.802	5.21e-04
GO:0140662 ATP-dependent protein folding chaperone	23	4.59e-10	0.750	7.40e-08
GO:0022627 cytosolic small ribosomal subunit	25	1.87e-10	-0.736	3.68e-08
GO:0022625 cytosolic large ribosomal subunit	40	2.85e-15	-0.721	1.69e-12
GO:0035145 exon-exon junction complex	10	7.85e-05	0.721	2.58e-03
GO:0070034 telomerase RNA binding	12	2.43e-05	0.704	8.96e-04
GO:0000228 nuclear chromosome	13	1.62e-05	0.690	6.85e-04
GO:0003678 DNA helicase activity	20	9.56e-08	0.689	7.36e-06
GO:0036121 double-stranded DNA helicase activity	11	8.29e-05	0.685	2.62e-03
GO:0002181 cytoplasmic translation	27	9.38e-10	-0.680	1.38e-07
GO:1990518 single-stranded 3’-5’ DNA helicase activity	11	1.11e-04	0.673	3.39e-03
GO:0000245 spliceosomal complex assembly	10	5.52e-04	0.631	1.21e-02
GO:0043627 response to estrogen	10	6.53e-04	0.622	1.37e-02
GO:0002230 positive regulation of defense response to virus by host	11	4.56e-04	0.610	1.03e-02
GO:0061749 forked DNA-dependent helicase activity	10	9.41e-04	0.604	1.79e-02
GO:0032212 positive regulation of telomere maintenance via telomerase	17	1.72e-05	0.602	6.95e-04
GO:0000793 condensed chromosome	13	1.95e-04	0.597	5.41e-03
GO:0017056 structural constituent of nuclear pore	19	1.02e-05	0.585	4.88e-04
GO:0007249 canonical NF-kappaB signal transduction	18	2.14e-05	0.579	8.10e-04
GO:0042026 protein refolding	12	7.42e-04	0.562	1.53e-02
GO:0009378 four-way junction helicase activity	13	4.55e-04	0.562	1.03e-02
GO:1990391 DNA repair complex	10	2.40e-03	0.554	3.46e-02
GO:0030199 collagen fibril organization	32	6.37e-08	-0.552	5.64e-06
GO:0007004 telomere maintenance via telomerase	11	1.52e-03	0.552	2.47e-02
GO:0007042 lysosomal lumen acidification	10	2.63e-03	-0.549	3.67e-02
GO:0016581 NuRD complex	10	2.96e-03	0.543	4.02e-02
GO:0004364 glutathione transferase activity	10	2.97e-03	-0.542	4.02e-02
GO:0070577 lysine-acetylated histone binding	16	1.93e-04	0.538	5.41e-03
GO:0061775 cohesin loader activity	24	8.19e-06	0.526	4.27e-04
GO:0003735 structural constituent of ribosome	118	8.72e-23	-0.524	1.55e-19
GO:0140584 chromatin extrusion motor activity	23	1.39e-05	0.523	5.99e-04
GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity	23	1.39e-05	0.523	5.99e-04
GO:0140849 ATP-dependent H2AZ histone chaperone activity	23	1.39e-05	0.523	5.99e-04
GO:0002218 activation of innate immune response	17	2.42e-04	0.514	6.39e-03
GO:0001654 eye development	17	2.73e-04	-0.510	6.90e-03
GO:0140588 chromatin looping	27	4.53e-06	0.510	2.51e-04
GO:0005581 collagen trimer	21	8.02e-05	-0.497	2.59e-03
GO:0007076 mitotic chromosome condensation	10	6.82e-03	0.494	7.25e-02
GO:0140658 ATP-dependent chromatin remodeler activity	11	4.56e-03	0.494	5.35e-02
GO:0070182 DNA polymerase binding	13	2.19e-03	0.491	3.32e-02
GO:0022626 cytosolic ribosome	13	2.22e-03	0.490	3.33e-02
GO:0045271 respiratory chain complex I	31	2.71e-06	-0.487	1.60e-04
GO:0061462 protein localization to lysosome	10	7.85e-03	-0.485	7.86e-02
GO:0016442 RISC complex	11	5.39e-03	0.485	6.16e-02
GO:0003689 DNA clamp loader activity	32	2.17e-06	0.484	1.37e-04
GO:0006406 mRNA export from nucleus	28	9.51e-06	0.483	4.68e-04
GO:1902774 late endosome to lysosome transport	10	8.17e-03	-0.483	8.02e-02
GO:0045116 protein neddylation	10	8.35e-03	-0.482	8.04e-02
GO:0005518 collagen binding	34	1.32e-06	-0.479	8.98e-05

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
GO:0045943 positive regulation of transcription by RNA polymerase I	11	7.55e-07	8.61e-01	5.35e-05
GO:0005049 nuclear export signal receptor activity	10	1.12e-05	8.02e-01	5.21e-04
GO:0140662 ATP-dependent protein folding chaperone	23	4.59e-10	7.50e-01	7.40e-08
GO:0022627 cytosolic small ribosomal subunit	25	1.87e-10	-7.36e-01	3.68e-08
GO:0022625 cytosolic large ribosomal subunit	40	2.85e-15	-7.21e-01	1.69e-12
GO:0035145 exon-exon junction complex	10	7.85e-05	7.21e-01	2.58e-03
GO:0070034 telomerase RNA binding	12	2.43e-05	7.04e-01	8.96e-04
GO:0000228 nuclear chromosome	13	1.62e-05	6.90e-01	6.85e-04
GO:0003678 DNA helicase activity	20	9.56e-08	6.89e-01	7.36e-06
GO:0036121 double-stranded DNA helicase activity	11	8.29e-05	6.85e-01	2.62e-03
GO:0002181 cytoplasmic translation	27	9.38e-10	-6.80e-01	1.38e-07
GO:1990518 single-stranded 3’-5’ DNA helicase activity	11	1.11e-04	6.73e-01	3.39e-03
GO:0000245 spliceosomal complex assembly	10	5.52e-04	6.31e-01	1.21e-02
GO:0043627 response to estrogen	10	6.53e-04	6.22e-01	1.37e-02
GO:0002230 positive regulation of defense response to virus by host	11	4.56e-04	6.10e-01	1.03e-02
GO:0061749 forked DNA-dependent helicase activity	10	9.41e-04	6.04e-01	1.79e-02
GO:0032212 positive regulation of telomere maintenance via telomerase	17	1.72e-05	6.02e-01	6.95e-04
GO:0000793 condensed chromosome	13	1.95e-04	5.97e-01	5.41e-03
GO:0017056 structural constituent of nuclear pore	19	1.02e-05	5.85e-01	4.88e-04
GO:0007249 canonical NF-kappaB signal transduction	18	2.14e-05	5.79e-01	8.10e-04
GO:0042026 protein refolding	12	7.42e-04	5.62e-01	1.53e-02
GO:0009378 four-way junction helicase activity	13	4.55e-04	5.62e-01	1.03e-02
GO:1990391 DNA repair complex	10	2.40e-03	5.54e-01	3.46e-02
GO:0030199 collagen fibril organization	32	6.37e-08	-5.52e-01	5.64e-06
GO:0007004 telomere maintenance via telomerase	11	1.52e-03	5.52e-01	2.47e-02
GO:0007042 lysosomal lumen acidification	10	2.63e-03	-5.49e-01	3.67e-02
GO:0016581 NuRD complex	10	2.96e-03	5.43e-01	4.02e-02
GO:0004364 glutathione transferase activity	10	2.97e-03	-5.42e-01	4.02e-02
GO:0070577 lysine-acetylated histone binding	16	1.93e-04	5.38e-01	5.41e-03
GO:0061775 cohesin loader activity	24	8.19e-06	5.26e-01	4.27e-04
GO:0003735 structural constituent of ribosome	118	8.72e-23	-5.24e-01	1.55e-19
GO:0140584 chromatin extrusion motor activity	23	1.39e-05	5.23e-01	5.99e-04
GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity	23	1.39e-05	5.23e-01	5.99e-04
GO:0140849 ATP-dependent H2AZ histone chaperone activity	23	1.39e-05	5.23e-01	5.99e-04
GO:0002218 activation of innate immune response	17	2.42e-04	5.14e-01	6.39e-03
GO:0001654 eye development	17	2.73e-04	-5.10e-01	6.90e-03
GO:0140588 chromatin looping	27	4.53e-06	5.10e-01	2.51e-04
GO:0005581 collagen trimer	21	8.02e-05	-4.97e-01	2.59e-03
GO:0007076 mitotic chromosome condensation	10	6.82e-03	4.94e-01	7.25e-02
GO:0140658 ATP-dependent chromatin remodeler activity	11	4.56e-03	4.94e-01	5.35e-02
GO:0070182 DNA polymerase binding	13	2.19e-03	4.91e-01	3.32e-02
GO:0022626 cytosolic ribosome	13	2.22e-03	4.90e-01	3.33e-02
GO:0045271 respiratory chain complex I	31	2.71e-06	-4.87e-01	1.60e-04
GO:0061462 protein localization to lysosome	10	7.85e-03	-4.85e-01	7.86e-02
GO:0016442 RISC complex	11	5.39e-03	4.85e-01	6.16e-02
GO:0003689 DNA clamp loader activity	32	2.17e-06	4.84e-01	1.37e-04
GO:0006406 mRNA export from nucleus	28	9.51e-06	4.83e-01	4.68e-04
GO:1902774 late endosome to lysosome transport	10	8.17e-03	-4.83e-01	8.02e-02
GO:0045116 protein neddylation	10	8.35e-03	-4.82e-01	8.04e-02
GO:0005518 collagen binding	34	1.32e-06	-4.79e-01	8.98e-05
GO:0006298 mismatch repair	16	9.18e-04	4.79e-01	1.79e-02
GO:0010608 post-transcriptional regulation of gene expression	11	6.34e-03	4.75e-01	7.02e-02
GO:0033962 P-body assembly	14	2.09e-03	4.75e-01	3.19e-02
GO:0030665 clathrin-coated vesicle membrane	11	6.38e-03	-4.75e-01	7.02e-02
GO:0006120 mitochondrial electron transport, NADH to ubiquinone	19	3.40e-04	-4.75e-01	8.24e-03
GO:0051881 regulation of mitochondrial membrane potential	14	2.28e-03	-4.71e-01	3.37e-02
GO:0032508 DNA duplex unwinding	44	7.14e-08	4.69e-01	6.02e-06
GO:0001707 mesoderm formation	15	1.83e-03	-4.65e-01	2.87e-02
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	13	4.04e-03	4.61e-01	4.97e-02
GO:0006412 translation	96	8.66e-15	-4.58e-01	3.07e-12
GO:0007339 binding of sperm to zona pellucida	11	8.52e-03	4.58e-01	8.12e-02
GO:0004683 calcium/calmodulin-dependent protein kinase activity	11	8.59e-03	-4.58e-01	8.14e-02
GO:0034727 piecemeal microautophagy of the nucleus	13	4.47e-03	-4.55e-01	5.34e-02
GO:0000422 autophagy of mitochondrion	14	3.34e-03	-4.53e-01	4.38e-02
GO:0071230 cellular response to amino acid stimulus	29	3.53e-05	-4.44e-01	1.25e-03
GO:0030020 extracellular matrix structural constituent conferring tensile strength	19	8.13e-04	-4.44e-01	1.60e-02
GO:0046907 intracellular transport	14	4.49e-03	-4.39e-01	5.34e-02
GO:0038061 non-canonical NF-kappaB signal transduction	11	1.19e-02	4.38e-01	9.58e-02
GO:0003724 RNA helicase activity	37	4.33e-06	4.37e-01	2.48e-04
GO:0006695 cholesterol biosynthetic process	16	2.53e-03	4.36e-01	3.58e-02
GO:0016446 somatic hypermutation of immunoglobulin genes	10	1.74e-02	4.34e-01	1.25e-01
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	15	3.75e-03	4.32e-01	4.74e-02
GO:0060337 type I interferon-mediated signaling pathway	10	1.80e-02	4.32e-01	1.27e-01
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway	11	1.31e-02	-4.32e-01	1.03e-01
GO:1903077 negative regulation of protein localization to plasma membrane	13	7.14e-03	-4.31e-01	7.40e-02
GO:0004386 helicase activity	40	2.60e-06	4.30e-01	1.59e-04
GO:0044331 cell-cell adhesion mediated by cadherin	11	1.40e-02	-4.28e-01	1.07e-01
GO:0051017 actin filament bundle assembly	12	1.04e-02	-4.27e-01	8.92e-02
GO:0005044 scavenger receptor activity	10	2.00e-02	-4.25e-01	1.37e-01
GO:0035278 miRNA-mediated gene silencing by inhibition of translation	12	1.17e-02	4.20e-01	9.48e-02
GO:0045815 transcription initiation-coupled chromatin remodeling	20	1.15e-03	4.20e-01	2.05e-02
GO:0031929 TOR signaling	13	8.93e-03	-4.19e-01	8.42e-02
GO:0043024 ribosomal small subunit binding	13	8.98e-03	4.19e-01	8.42e-02
GO:0060047 heart contraction	10	2.19e-02	-4.19e-01	1.42e-01
GO:0003774 cytoskeletal motor activity	14	6.91e-03	-4.17e-01	7.25e-02
GO:0030501 positive regulation of bone mineralization	13	9.51e-03	-4.15e-01	8.51e-02
GO:0004602 glutathione peroxidase activity	12	1.28e-02	-4.15e-01	1.01e-01
GO:0000792 heterochromatin	19	1.77e-03	4.14e-01	2.82e-02
GO:0006749 glutathione metabolic process	15	5.50e-03	-4.14e-01	6.25e-02
GO:0046961 proton-transporting ATPase activity, rotational mechanism	14	7.32e-03	-4.14e-01	7.54e-02
GO:0042277 peptide binding	10	2.39e-02	4.13e-01	1.48e-01
GO:0005544 calcium-dependent phospholipid binding	21	1.09e-03	-4.12e-01	1.99e-02
GO:0006346 DNA methylation-dependent constitutive heterochromatin formation	10	2.45e-02	4.11e-01	1.51e-01
GO:0007131 reciprocal meiotic recombination	12	1.38e-02	4.11e-01	1.06e-01
GO:0016973 poly(A)+ mRNA export from nucleus	13	1.05e-02	4.10e-01	8.92e-02
GO:0042254 ribosome biogenesis	16	4.83e-03	4.07e-01	5.63e-02
GO:0071108 protein K48-linked deubiquitination	15	6.48e-03	4.06e-01	7.05e-02
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	21	1.29e-03	4.06e-01	2.19e-02
GO:0045190 isotype switching	13	1.14e-02	4.06e-01	9.28e-02
GO:0004857 enzyme inhibitor activity	12	1.50e-02	4.05e-01	1.11e-01
GO:0070530 K63-linked polyubiquitin modification-dependent protein binding	17	3.84e-03	4.05e-01	4.80e-02
GO:0007492 endoderm development	11	2.01e-02	4.05e-01	1.37e-01
GO:0008137 NADH dehydrogenase (ubiquinone) activity	10	2.68e-02	-4.04e-01	1.60e-01
GO:0048306 calcium-dependent protein binding	20	1.79e-03	-4.04e-01	2.83e-02
GO:0032728 positive regulation of interferon-beta production	15	6.85e-03	4.03e-01	7.25e-02
GO:0007611 learning or memory	15	6.90e-03	-4.03e-01	7.25e-02
GO:0070085 glycosylation	14	9.62e-03	-4.00e-01	8.53e-02
GO:0006805 xenobiotic metabolic process	17	4.43e-03	-3.99e-01	5.34e-02
GO:0090303 positive regulation of wound healing	11	2.22e-02	-3.98e-01	1.43e-01
GO:0000400 four-way junction DNA binding	14	9.93e-03	3.98e-01	8.71e-02
GO:0015030 Cajal body	26	4.58e-04	3.97e-01	1.03e-02
GO:0051315 attachment of mitotic spindle microtubules to kinetochore	10	3.02e-02	3.96e-01	1.71e-01
GO:0006334 nucleosome assembly	27	3.77e-04	3.95e-01	9.03e-03
GO:0141198 protein branched polyubiquitination	13	1.42e-02	3.93e-01	1.07e-01
GO:0048477 oogenesis	14	1.14e-02	3.91e-01	9.28e-02
GO:0035371 microtubule plus-end	12	1.94e-02	3.90e-01	1.34e-01
GO:0097718 disordered domain specific binding	15	9.41e-03	3.87e-01	8.51e-02
GO:0006337 nucleosome disassembly	10	3.40e-02	3.87e-01	1.85e-01
GO:0003180 aortic valve morphogenesis	10	3.45e-02	-3.86e-01	1.86e-01
GO:0060236 regulation of mitotic spindle organization	12	2.08e-02	3.86e-01	1.39e-01
GO:0007338 single fertilization	19	3.94e-03	-3.82e-01	4.88e-02
GO:0000380 alternative mRNA splicing, via spliceosome	16	8.19e-03	3.82e-01	8.02e-02
GO:0050840 extracellular matrix binding	17	6.66e-03	-3.80e-01	7.15e-02
GO:0006936 muscle contraction	12	2.31e-02	-3.79e-01	1.46e-01
GO:0007608 sensory perception of smell	11	3.04e-02	-3.77e-01	1.71e-01
GO:0010569 regulation of double-strand break repair via homologous recombination	10	4.08e-02	3.74e-01	2.10e-01
GO:0006913 nucleocytoplasmic transport	18	6.42e-03	3.71e-01	7.03e-02
GO:0006906 vesicle fusion	15	1.29e-02	-3.71e-01	1.01e-01
GO:0005179 hormone activity	13	2.19e-02	-3.67e-01	1.42e-01
GO:0016514 SWI/SNF complex	20	4.55e-03	3.67e-01	5.35e-02
GO:0032981 mitochondrial respiratory chain complex I assembly	38	9.84e-05	-3.65e-01	3.06e-03
GO:0044344 cellular response to fibroblast growth factor stimulus	10	4.59e-02	-3.65e-01	2.26e-01
GO:0032039 integrator complex	15	1.47e-02	3.64e-01	1.10e-01
GO:0006275 regulation of DNA replication	24	2.08e-03	3.63e-01	3.19e-02
GO:0003688 DNA replication origin binding	12	2.97e-02	3.62e-01	1.69e-01
GO:0034237 protein kinase A regulatory subunit binding	15	1.55e-02	3.61e-01	1.14e-01
GO:0000786 nucleosome	16	1.24e-02	3.61e-01	9.88e-02
GO:0005680 anaphase-promoting complex	13	2.45e-02	3.60e-01	1.51e-01
GO:0031573 mitotic intra-S DNA damage checkpoint signaling	11	3.97e-02	3.58e-01	2.09e-01
GO:0007163 establishment or maintenance of cell polarity	13	2.53e-02	-3.58e-01	1.53e-01
GO:0030016 myofibril	14	2.05e-02	-3.58e-01	1.38e-01
GO:0030324 lung development	35	2.60e-04	-3.57e-01	6.67e-03
GO:0001221 transcription coregulator binding	17	1.11e-02	3.56e-01	9.27e-02
GO:0032266 phosphatidylinositol-3-phosphate binding	32	5.20e-04	-3.55e-01	1.15e-02
GO:0030687 preribosome, large subunit precursor	12	3.40e-02	3.53e-01	1.85e-01
GO:0004435 phosphatidylinositol phospholipase C activity	12	3.40e-02	3.53e-01	1.85e-01
GO:0050890 cognition	18	9.51e-03	3.53e-01	8.51e-02
GO:0005721 pericentric heterochromatin	18	9.70e-03	3.52e-01	8.55e-02
GO:0051781 positive regulation of cell division	13	2.82e-02	-3.51e-01	1.64e-01
GO:0035025 positive regulation of Rho protein signal transduction	10	5.69e-02	-3.48e-01	2.57e-01
GO:0032420 stereocilium	14	2.51e-02	-3.46e-01	1.53e-01
GO:0000723 telomere maintenance	29	1.30e-03	3.45e-01	2.19e-02
GO:0035613 RNA stem-loop binding	11	4.97e-02	3.42e-01	2.39e-01
GO:0003785 actin monomer binding	14	2.72e-02	-3.41e-01	1.60e-01
GO:0042474 middle ear morphogenesis	10	6.22e-02	-3.41e-01	2.71e-01
GO:0005840 ribosome	43	1.24e-04	-3.38e-01	3.73e-03
GO:0032968 positive regulation of transcription elongation by RNA polymerase II	15	2.36e-02	3.38e-01	1.48e-01
GO:0008139 nuclear localization sequence binding	13	3.51e-02	3.38e-01	1.88e-01
GO:0001968 fibronectin binding	10	6.46e-02	3.37e-01	2.77e-01
GO:0051028 mRNA transport	27	2.49e-03	3.36e-01	3.56e-02
GO:0042393 histone binding	94	2.04e-08	3.35e-01	2.01e-06
GO:0005694 chromosome	76	4.64e-07	3.35e-01	3.43e-05
GO:0001568 blood vessel development	19	1.22e-02	-3.32e-01	9.78e-02
GO:0004867 serine-type endopeptidase inhibitor activity	23	5.98e-03	-3.31e-01	6.71e-02
GO:0005201 extracellular matrix structural constituent	13	3.92e-02	-3.30e-01	2.07e-01
GO:1904115 axon cytoplasm	25	4.27e-03	-3.30e-01	5.18e-02
GO:0030515 snoRNA binding	14	3.30e-02	3.29e-01	1.84e-01
GO:0048870 cell motility	12	4.86e-02	-3.29e-01	2.37e-01
GO:0006268 DNA unwinding involved in DNA replication	14	3.34e-02	3.28e-01	1.85e-01
GO:0044389 ubiquitin-like protein ligase binding	16	2.32e-02	3.28e-01	1.47e-01
GO:0007129 homologous chromosome pairing at meiosis	13	4.18e-02	3.26e-01	2.13e-01
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors	18	1.66e-02	3.26e-01	1.21e-01
GO:0009306 protein secretion	20	1.20e-02	-3.25e-01	9.61e-02
GO:0042273 ribosomal large subunit biogenesis	22	8.44e-03	3.24e-01	8.08e-02
GO:0031210 phosphatidylcholine binding	18	1.73e-02	-3.24e-01	1.25e-01
GO:0005902 microvillus	28	3.03e-03	-3.24e-01	4.07e-02
GO:0034497 protein localization to phagophore assembly site	11	6.32e-02	-3.24e-01	2.74e-01
GO:0017053 transcription repressor complex	34	1.11e-03	3.23e-01	2.01e-02
GO:0008094 ATP-dependent activity, acting on DNA	11	6.42e-02	3.22e-01	2.76e-01
GO:0017116 single-stranded DNA helicase activity	16	2.59e-02	3.22e-01	1.56e-01
GO:0045184 establishment of protein localization	17	2.19e-02	-3.21e-01	1.42e-01
GO:0016579 protein deubiquitination	28	3.31e-03	3.21e-01	4.37e-02
GO:0035267 NuA4 histone acetyltransferase complex	18	1.87e-02	3.20e-01	1.30e-01
GO:0003727 single-stranded RNA binding	21	1.11e-02	3.20e-01	9.27e-02
GO:0030225 macrophage differentiation	11	6.63e-02	-3.20e-01	2.81e-01
GO:0005828 kinetochore microtubule	10	8.02e-02	-3.20e-01	3.15e-01
GO:0003684 damaged DNA binding	34	1.33e-03	3.18e-01	2.22e-02
GO:0045722 positive regulation of gluconeogenesis	11	6.80e-02	-3.18e-01	2.85e-01
GO:0016363 nuclear matrix	46	2.00e-04	3.17e-01	5.46e-03
GO:0005762 mitochondrial large ribosomal subunit	38	7.80e-04	-3.15e-01	1.57e-02
GO:0061709 reticulophagy	15	3.51e-02	-3.14e-01	1.88e-01
GO:0031902 late endosome membrane	67	9.01e-06	-3.14e-01	4.56e-04
GO:0032720 negative regulation of tumor necrosis factor production	18	2.17e-02	3.13e-01	1.42e-01
GO:0009653 anatomical structure morphogenesis	21	1.32e-02	-3.13e-01	1.03e-01
GO:0005875 microtubule associated complex	10	8.72e-02	3.12e-01	3.32e-01
GO:0030863 cortical cytoskeleton	10	8.78e-02	-3.12e-01	3.32e-01
GO:0140861 DNA repair-dependent chromatin remodeling	14	4.38e-02	3.11e-01	2.22e-01
GO:0034704 calcium channel complex	10	8.93e-02	-3.10e-01	3.34e-01
GO:0070411 I-SMAD binding	11	7.48e-02	-3.10e-01	3.00e-01
GO:0030127 COPII vesicle coat	10	9.23e-02	-3.07e-01	3.37e-01
GO:0005643 nuclear pore	33	2.28e-03	3.07e-01	3.37e-02
GO:2001222 regulation of neuron migration	10	9.32e-02	3.07e-01	3.37e-01
GO:0031669 cellular response to nutrient levels	13	5.61e-02	3.06e-01	2.57e-01
GO:0035855 megakaryocyte development	10	9.40e-02	3.06e-01	3.38e-01
GO:0140664 ATP-dependent DNA damage sensor activity	14	4.84e-02	3.05e-01	2.36e-01
GO:0071013 catalytic step 2 spliceosome	52	1.47e-04	3.04e-01	4.28e-03
GO:0140374 antiviral innate immune response	20	1.85e-02	3.04e-01	1.30e-01
GO:0002062 chondrocyte differentiation	22	1.36e-02	-3.04e-01	1.06e-01
GO:0030282 bone mineralization	24	1.01e-02	-3.03e-01	8.78e-02
GO:0008233 peptidase activity	10	9.71e-02	-3.03e-01	3.46e-01
GO:0001786 phosphatidylserine binding	24	1.03e-02	-3.03e-01	8.86e-02
GO:0015908 fatty acid transport	11	8.25e-02	3.02e-01	3.24e-01
GO:0005977 glycogen metabolic process	13	5.93e-02	-3.02e-01	2.63e-01
GO:0034314 Arp2/3 complex-mediated actin nucleation	11	8.33e-02	-3.02e-01	3.25e-01
GO:0006260 DNA replication	34	2.39e-03	3.01e-01	3.46e-02
GO:0031491 nucleosome binding	25	9.31e-03	3.01e-01	8.51e-02
GO:0046966 nuclear thyroid hormone receptor binding	15	4.42e-02	3.00e-01	2.22e-01
GO:0034045 phagophore assembly site membrane	12	7.25e-02	-2.99e-01	2.95e-01
GO:0045292 mRNA cis splicing, via spliceosome	13	6.17e-02	2.99e-01	2.69e-01
GO:0045727 positive regulation of translation	36	1.96e-03	2.98e-01	3.04e-02
GO:0031116 positive regulation of microtubule polymerization	11	8.69e-02	2.98e-01	3.31e-01
GO:0042162 telomeric DNA binding	20	2.13e-02	2.97e-01	1.41e-01
GO:0032206 positive regulation of telomere maintenance	14	5.48e-02	2.96e-01	2.55e-01
GO:0090734 site of DNA damage	22	1.61e-02	2.96e-01	1.18e-01
GO:0016485 protein processing	40	1.19e-03	-2.96e-01	2.07e-02
GO:1902018 negative regulation of cilium assembly	14	5.57e-02	2.95e-01	2.56e-01
GO:0051209 release of sequestered calcium ion into cytosol	20	2.25e-02	2.95e-01	1.44e-01
GO:0000077 DNA damage checkpoint signaling	26	9.46e-03	2.94e-01	8.51e-02
GO:0098869 cellular oxidant detoxification	28	7.10e-03	-2.94e-01	7.40e-02
GO:0040014 regulation of multicellular organism growth	12	7.81e-02	-2.94e-01	3.10e-01
GO:2000811 negative regulation of anoikis	10	1.08e-01	2.94e-01	3.67e-01
GO:0016460 myosin II complex	12	7.85e-02	-2.93e-01	3.10e-01
GO:0032433 filopodium tip	10	1.08e-01	-2.93e-01	3.67e-01
GO:0007094 mitotic spindle assembly checkpoint signaling	19	2.69e-02	2.93e-01	1.60e-01
GO:0003777 microtubule motor activity	23	1.51e-02	2.93e-01	1.11e-01
GO:2000300 regulation of synaptic vesicle exocytosis	19	2.72e-02	-2.93e-01	1.60e-01
GO:0051059 NF-kappaB binding	22	1.77e-02	2.92e-01	1.26e-01
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	13	6.81e-02	2.92e-01	2.85e-01
GO:0016459 myosin complex	26	1.03e-02	-2.91e-01	8.86e-02
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding	21	2.11e-02	-2.91e-01	1.40e-01
GO:0006270 DNA replication initiation	19	2.87e-02	2.90e-01	1.66e-01
GO:0031507 heterochromatin formation	27	9.19e-03	2.90e-01	8.51e-02
GO:0045335 phagocytic vesicle	36	2.71e-03	-2.89e-01	3.76e-02
GO:0001578 microtubule bundle formation	15	5.35e-02	2.88e-01	2.50e-01
GO:0001676 long-chain fatty acid metabolic process	11	9.81e-02	2.88e-01	3.47e-01
GO:0005245 voltage-gated calcium channel activity	11	9.84e-02	2.88e-01	3.47e-01
GO:0090307 mitotic spindle assembly	30	6.61e-03	2.87e-01	7.14e-02
GO:0003725 double-stranded RNA binding	44	1.01e-03	2.86e-01	1.87e-02
GO:0033617 mitochondrial cytochrome c oxidase assembly	13	7.42e-02	-2.86e-01	2.99e-01
GO:0005771 multivesicular body	21	2.33e-02	-2.86e-01	1.47e-01
GO:0050830 defense response to Gram-positive bacterium	15	5.54e-02	2.86e-01	2.56e-01
GO:0044183 protein folding chaperone	21	2.36e-02	2.85e-01	1.48e-01
GO:0099175 regulation of postsynapse organization	20	2.75e-02	-2.85e-01	1.61e-01
GO:0097431 mitotic spindle pole	27	1.05e-02	2.85e-01	8.92e-02
GO:0016235 aggresome	17	4.23e-02	2.85e-01	2.15e-01
GO:0050661 NADP binding	13	7.86e-02	-2.82e-01	3.10e-01
GO:0007095 mitotic G2 DNA damage checkpoint signaling	30	7.61e-03	2.82e-01	7.79e-02
GO:0061631 ubiquitin conjugating enzyme activity	24	1.72e-02	-2.81e-01	1.25e-01
GO:0032585 multivesicular body membrane	12	9.20e-02	-2.81e-01	3.37e-01
GO:0098686 hippocampal mossy fiber to CA3 synapse	17	4.50e-02	-2.81e-01	2.24e-01
GO:0006413 translational initiation	30	7.77e-03	2.81e-01	7.83e-02
GO:0042593 glucose homeostasis	42	1.64e-03	-2.81e-01	2.65e-02
GO:0030897 HOPS complex	10	1.25e-01	-2.80e-01	3.96e-01
GO:0140693 molecular condensate scaffold activity	24	1.75e-02	2.80e-01	1.25e-01
GO:0071222 cellular response to lipopolysaccharide	45	1.18e-03	2.80e-01	2.07e-02
GO:0005978 glycogen biosynthetic process	11	1.11e-01	-2.77e-01	3.74e-01
GO:0018279 protein N-linked glycosylation via asparagine	11	1.12e-01	-2.77e-01	3.74e-01
GO:0012506 vesicle membrane	15	6.34e-02	-2.77e-01	2.74e-01
GO:0051290 protein heterotetramerization	10	1.30e-01	2.77e-01	4.06e-01
GO:0070006 metalloaminopeptidase activity	15	6.41e-02	-2.76e-01	2.76e-01
GO:0071005 U2-type precatalytic spliceosome	31	7.96e-03	2.75e-01	7.89e-02
GO:0016226 iron-sulfur cluster assembly	17	4.93e-02	-2.75e-01	2.39e-01
GO:0006364 rRNA processing	65	1.30e-04	2.75e-01	3.84e-03
GO:0051302 regulation of cell division	11	1.15e-01	2.75e-01	3.77e-01
GO:0070372 regulation of ERK1 and ERK2 cascade	13	8.86e-02	2.73e-01	3.33e-01
GO:0070064 proline-rich region binding	10	1.36e-01	2.72e-01	4.14e-01
GO:0031526 brush border membrane	12	1.03e-01	2.72e-01	3.56e-01
GO:0060382 regulation of DNA strand elongation	10	1.36e-01	2.72e-01	4.14e-01
GO:0006099 tricarboxylic acid cycle	19	4.03e-02	-2.72e-01	2.10e-01
GO:0004177 aminopeptidase activity	13	9.01e-02	-2.72e-01	3.34e-01
GO:0080025 phosphatidylinositol-3,5-bisphosphate binding	15	6.90e-02	-2.71e-01	2.88e-01
GO:1905564 positive regulation of vascular endothelial cell proliferation	10	1.38e-01	2.71e-01	4.14e-01
GO:1902600 proton transmembrane transport	59	3.24e-04	-2.71e-01	8.10e-03
GO:0032418 lysosome localization	23	2.49e-02	-2.70e-01	1.52e-01
GO:0048568 embryonic organ development	15	7.01e-02	-2.70e-01	2.90e-01
GO:0060045 positive regulation of cardiac muscle cell proliferation	13	9.18e-02	2.70e-01	3.37e-01
GO:0001570 vasculogenesis	26	1.74e-02	2.70e-01	1.25e-01
GO:0005764 lysosome	133	8.38e-08	-2.69e-01	6.75e-06
GO:0009888 tissue development	18	4.79e-02	2.69e-01	2.35e-01
GO:0010494 cytoplasmic stress granule	58	3.92e-04	2.69e-01	9.25e-03
GO:0044295 axonal growth cone	11	1.24e-01	2.68e-01	3.95e-01
GO:0051321 meiotic cell cycle	21	3.35e-02	2.68e-01	1.85e-01
GO:0031145 anaphase-promoting complex-dependent catabolic process	14	8.34e-02	2.67e-01	3.25e-01
GO:0071347 cellular response to interleukin-1	17	5.73e-02	2.66e-01	2.58e-01
GO:0062023 collagen-containing extracellular matrix	76	6.20e-05	-2.66e-01	2.07e-03
GO:2000786 positive regulation of autophagosome assembly	14	8.55e-02	-2.65e-01	3.28e-01
GO:0002039 p53 binding	44	2.33e-03	2.65e-01	3.41e-02
GO:0051382 kinetochore assembly	11	1.28e-01	2.65e-01	4.02e-01
GO:0000398 mRNA splicing, via spliceosome	87	1.98e-05	2.65e-01	7.81e-04
GO:0051537 2 iron, 2 sulfur cluster binding	17	5.96e-02	-2.64e-01	2.63e-01
GO:2000737 negative regulation of stem cell differentiation	12	1.14e-01	2.64e-01	3.77e-01
GO:0008201 heparin binding	55	7.50e-04	-2.63e-01	1.53e-02
GO:0009749 response to glucose	14	8.90e-02	2.63e-01	3.34e-01
GO:0048026 positive regulation of mRNA splicing, via spliceosome	12	1.16e-01	2.62e-01	3.79e-01
GO:0019827 stem cell population maintenance	21	3.83e-02	2.61e-01	2.03e-01
GO:0045821 positive regulation of glycolytic process	10	1.53e-01	-2.61e-01	4.33e-01
GO:0071711 basement membrane organization	11	1.35e-01	-2.60e-01	4.14e-01
GO:0001046 core promoter sequence-specific DNA binding	11	1.35e-01	2.60e-01	4.14e-01
GO:0045070 positive regulation of viral genome replication	19	4.98e-02	2.60e-01	2.39e-01
GO:0032007 negative regulation of TOR signaling	19	5.02e-02	-2.60e-01	2.39e-01
GO:1905168 positive regulation of double-strand break repair via homologous recombination	25	2.49e-02	2.59e-01	1.52e-01
GO:0010811 positive regulation of cell-substrate adhesion	13	1.07e-01	-2.58e-01	3.67e-01
GO:0003714 transcription corepressor activity	101	7.82e-06	2.58e-01	4.20e-04
GO:0015813 L-glutamate transmembrane transport	11	1.39e-01	2.58e-01	4.16e-01
GO:0061512 protein localization to cilium	22	3.67e-02	-2.57e-01	1.96e-01
GO:0048704 embryonic skeletal system morphogenesis	18	5.89e-02	-2.57e-01	2.62e-01
GO:0006396 RNA processing	21	4.17e-02	2.57e-01	2.13e-01
GO:0030150 protein import into mitochondrial matrix	12	1.24e-01	-2.57e-01	3.95e-01
GO:0042307 positive regulation of protein import into nucleus	24	2.98e-02	2.56e-01	1.69e-01
GO:0033627 cell adhesion mediated by integrin	22	3.75e-02	-2.56e-01	2.00e-01
GO:0016829 lyase activity	15	8.79e-02	-2.55e-01	3.32e-01
GO:0005178 integrin binding	65	4.07e-04	-2.54e-01	9.50e-03
GO:0032735 positive regulation of interleukin-12 production	12	1.29e-01	2.53e-01	4.04e-01
GO:0060379 cardiac muscle cell myoblast differentiation	10	1.67e-01	2.52e-01	4.53e-01
GO:0000939 inner kinetochore	10	1.68e-01	2.52e-01	4.53e-01
GO:0005743 mitochondrial inner membrane	181	6.07e-09	-2.51e-01	7.69e-07
GO:1990498 mitotic spindle microtubule	10	1.69e-01	2.51e-01	4.55e-01
GO:0097038 perinuclear endoplasmic reticulum	10	1.70e-01	-2.51e-01	4.55e-01
GO:0004843 cysteine-type deubiquitinase activity	58	9.72e-04	2.51e-01	1.83e-02
GO:0006302 double-strand break repair	45	3.80e-03	2.49e-01	4.78e-02
GO:0010761 fibroblast migration	10	1.73e-01	-2.49e-01	4.57e-01
GO:0006744 ubiquinone biosynthetic process	11	1.53e-01	-2.49e-01	4.33e-01
GO:0016887 ATP hydrolysis activity	216	3.25e-10	2.49e-01	5.75e-08
GO:0060348 bone development	27	2.55e-02	-2.48e-01	1.54e-01
GO:0000987 cis-regulatory region sequence-specific DNA binding	21	4.90e-02	2.48e-01	2.38e-01
GO:0071806 protein transmembrane transport	12	1.37e-01	-2.48e-01	4.14e-01
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	12	1.37e-01	2.48e-01	4.14e-01
GO:0045765 regulation of angiogenesis	11	1.56e-01	2.47e-01	4.36e-01
GO:0034113 heterotypic cell-cell adhesion	11	1.56e-01	-2.47e-01	4.36e-01
GO:0045739 positive regulation of DNA repair	20	5.64e-02	2.47e-01	2.57e-01
GO:0035994 response to muscle stretch	10	1.78e-01	2.46e-01	4.61e-01
GO:0006281 DNA repair	95	3.46e-05	2.46e-01	1.25e-03
GO:0050769 positive regulation of neurogenesis	12	1.41e-01	2.46e-01	4.19e-01
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator	11	1.59e-01	2.45e-01	4.41e-01
GO:0000956 nuclear-transcribed mRNA catabolic process	12	1.42e-01	2.45e-01	4.20e-01
GO:0006352 DNA-templated transcription initiation	11	1.60e-01	2.45e-01	4.41e-01
GO:0005901 caveola	28	2.53e-02	-2.44e-01	1.53e-01
GO:0050829 defense response to Gram-negative bacterium	11	1.61e-01	2.44e-01	4.42e-01
GO:0043531 ADP binding	21	5.28e-02	2.44e-01	2.48e-01
GO:0045824 negative regulation of innate immune response	16	9.14e-02	2.44e-01	3.36e-01
GO:0035198 miRNA binding	20	5.99e-02	2.43e-01	2.63e-01
GO:0007601 visual perception	37	1.06e-02	-2.43e-01	8.94e-02
GO:0001673 male germ cell nucleus	27	2.93e-02	2.42e-01	1.67e-01
GO:0051536 iron-sulfur cluster binding	12	1.46e-01	-2.42e-01	4.27e-01
GO:0015035 protein-disulfide reductase activity	14	1.17e-01	-2.42e-01	3.79e-01
GO:0051216 cartilage development	21	5.51e-02	-2.42e-01	2.55e-01
GO:0031334 positive regulation of protein-containing complex assembly	17	8.44e-02	-2.42e-01	3.26e-01
GO:0009791 post-embryonic development	37	1.09e-02	2.42e-01	9.19e-02
GO:0000421 autophagosome membrane	23	4.51e-02	-2.41e-01	2.24e-01
GO:0005666 RNA polymerase III complex	12	1.48e-01	2.41e-01	4.29e-01
GO:0043425 bHLH transcription factor binding	10	1.87e-01	2.41e-01	4.73e-01
GO:0004402 histone acetyltransferase activity	11	1.67e-01	2.40e-01	4.53e-01
GO:0003899 DNA-directed 5’-3’ RNA polymerase activity	10	1.89e-01	2.40e-01	4.74e-01
GO:0005604 basement membrane	44	6.06e-03	-2.39e-01	6.76e-02
GO:0031490 chromatin DNA binding	41	8.26e-03	2.38e-01	8.02e-02
GO:0050673 epithelial cell proliferation	20	6.53e-02	2.38e-01	2.78e-01
GO:0002040 sprouting angiogenesis	19	7.31e-02	2.38e-01	2.96e-01
GO:0032757 positive regulation of interleukin-8 production	17	9.02e-02	-2.37e-01	3.34e-01
GO:0006869 lipid transport	29	2.70e-02	-2.37e-01	1.60e-01
GO:0031201 SNARE complex	33	1.85e-02	-2.37e-01	1.30e-01
GO:0000176 nuclear exosome (RNase complex)	12	1.56e-01	2.37e-01	4.36e-01
GO:0048513 animal organ development	11	1.74e-01	2.37e-01	4.59e-01
GO:0001937 negative regulation of endothelial cell proliferation	12	1.57e-01	2.36e-01	4.38e-01
GO:0048015 phosphatidylinositol-mediated signaling	18	8.37e-02	2.36e-01	3.25e-01
GO:0017147 Wnt-protein binding	17	9.28e-02	-2.36e-01	3.37e-01
GO:0060391 positive regulation of SMAD protein signal transduction	13	1.42e-01	-2.35e-01	4.20e-01
GO:0001965 G-protein alpha-subunit binding	10	1.99e-01	-2.35e-01	4.85e-01
GO:0016180 snRNA processing	10	1.99e-01	2.35e-01	4.85e-01
GO:0006325 chromatin organization	66	1.00e-03	2.34e-01	1.87e-02
GO:0006397 mRNA processing	72	6.19e-04	2.33e-01	1.34e-02
GO:0070498 interleukin-1-mediated signaling pathway	11	1.82e-01	-2.33e-01	4.66e-01
GO:0030855 epithelial cell differentiation	28	3.36e-02	-2.32e-01	1.85e-01
GO:0006979 response to oxidative stress	49	5.01e-03	-2.32e-01	5.80e-02
GO:0030330 DNA damage response, signal transduction by p53 class mediator	12	1.64e-01	2.32e-01	4.49e-01
GO:0046332 SMAD binding	23	5.44e-02	-2.32e-01	2.54e-01
GO:0006446 regulation of translational initiation	17	9.92e-02	2.31e-01	3.48e-01
GO:0003887 DNA-directed DNA polymerase activity	16	1.10e-01	2.31e-01	3.71e-01
GO:0030837 negative regulation of actin filament polymerization	14	1.36e-01	-2.30e-01	4.14e-01
GO:0007259 cell surface receptor signaling pathway via JAK-STAT	21	6.77e-02	2.30e-01	2.85e-01
GO:0043138 3’-5’ DNA helicase activity	10	2.07e-01	2.30e-01	4.92e-01
GO:0019838 growth factor binding	11	1.86e-01	2.30e-01	4.72e-01
GO:0003682 chromatin binding	238	1.11e-09	2.30e-01	1.52e-07
GO:0071897 DNA biosynthetic process	12	1.68e-01	2.30e-01	4.54e-01
GO:0005615 extracellular space	404	3.82e-15	-2.29e-01	1.69e-12
GO:0005847 mRNA cleavage and polyadenylation specificity factor complex	11	1.89e-01	2.29e-01	4.74e-01
GO:0005879 axonemal microtubule	10	2.11e-01	2.29e-01	4.94e-01
GO:0070131 positive regulation of mitochondrial translation	10	2.11e-01	-2.29e-01	4.94e-01
GO:0045648 positive regulation of erythrocyte differentiation	18	9.33e-02	2.29e-01	3.37e-01
GO:0015914 phospholipid transport	26	4.39e-02	-2.28e-01	2.22e-01
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT	13	1.54e-01	2.28e-01	4.33e-01
GO:0035770 ribonucleoprotein granule	13	1.54e-01	2.28e-01	4.33e-01
GO:0070373 negative regulation of ERK1 and ERK2 cascade	30	3.05e-02	2.28e-01	1.71e-01
GO:0019888 protein phosphatase regulator activity	16	1.14e-01	2.28e-01	3.77e-01
GO:0051560 mitochondrial calcium ion homeostasis	13	1.54e-01	-2.28e-01	4.33e-01
GO:0004181 metallocarboxypeptidase activity	12	1.72e-01	-2.28e-01	4.55e-01
GO:0050766 positive regulation of phagocytosis	14	1.40e-01	-2.28e-01	4.17e-01
GO:0051016 barbed-end actin filament capping	16	1.15e-01	-2.28e-01	3.77e-01
GO:0045296 cadherin binding	29	3.42e-02	-2.27e-01	1.85e-01
GO:0055074 calcium ion homeostasis	17	1.05e-01	-2.27e-01	3.62e-01
GO:0032040 small-subunit processome	59	2.61e-03	2.27e-01	3.67e-02
GO:0051453 regulation of intracellular pH	14	1.42e-01	-2.27e-01	4.20e-01
GO:1990841 promoter-specific chromatin binding	34	2.25e-02	2.26e-01	1.44e-01
GO:0032922 circadian regulation of gene expression	34	2.29e-02	2.26e-01	1.46e-01
GO:0003677 DNA binding	336	1.52e-12	2.25e-01	3.42e-10
GO:0007026 negative regulation of microtubule depolymerization	17	1.08e-01	2.25e-01	3.67e-01
GO:0035914 skeletal muscle cell differentiation	24	5.66e-02	2.25e-01	2.57e-01
GO:0016491 oxidoreductase activity	47	7.74e-03	-2.25e-01	7.83e-02
GO:0071466 cellular response to xenobiotic stimulus	24	5.69e-02	2.25e-01	2.57e-01
GO:0008320 protein transmembrane transporter activity	11	1.97e-01	2.25e-01	4.85e-01
GO:0097194 execution phase of apoptosis	10	2.20e-01	2.24e-01	5.04e-01
GO:0006635 fatty acid beta-oxidation	26	4.81e-02	-2.24e-01	2.35e-01
GO:0008380 RNA splicing	47	7.97e-03	2.24e-01	7.89e-02
GO:0022604 regulation of cell morphogenesis	14	1.48e-01	2.24e-01	4.28e-01
GO:0030507 spectrin binding	13	1.63e-01	-2.23e-01	4.48e-01
GO:0031466 Cul5-RING ubiquitin ligase complex	11	2.00e-01	-2.23e-01	4.85e-01
GO:1990782 protein tyrosine kinase binding	15	1.36e-01	-2.22e-01	4.14e-01
GO:0000974 Prp19 complex	10	2.24e-01	2.22e-01	5.08e-01
GO:0035024 negative regulation of Rho protein signal transduction	14	1.50e-01	-2.22e-01	4.29e-01
GO:0006094 gluconeogenesis	20	8.69e-02	-2.21e-01	3.31e-01
GO:0070403 NAD+ binding	11	2.04e-01	-2.21e-01	4.90e-01
GO:0003690 double-stranded DNA binding	35	2.37e-02	2.21e-01	1.48e-01
GO:0045454 cell redox homeostasis	20	8.80e-02	-2.20e-01	3.32e-01
GO:0003713 transcription coactivator activity	128	1.73e-05	2.20e-01	6.95e-04
GO:0010314 phosphatidylinositol-5-phosphate binding	11	2.06e-01	-2.20e-01	4.92e-01
GO:0050905 neuromuscular process	10	2.29e-01	-2.20e-01	5.14e-01
GO:0000423 mitophagy	31	3.58e-02	-2.18e-01	1.92e-01
GO:0005484 SNAP receptor activity	26	5.50e-02	-2.17e-01	2.55e-01
GO:0048010 vascular endothelial growth factor receptor signaling pathway	13	1.75e-01	2.17e-01	4.60e-01
GO:0008542 visual learning	20	9.27e-02	2.17e-01	3.37e-01
GO:0000781 chromosome, telomeric region	75	1.16e-03	2.17e-01	2.05e-02
GO:0031297 replication fork processing	26	5.57e-02	2.17e-01	2.56e-01
GO:0000785 chromatin	241	7.56e-09	2.17e-01	8.93e-07
GO:2000377 regulation of reactive oxygen species metabolic process	10	2.36e-01	-2.16e-01	5.24e-01
GO:0097225 sperm midpiece	15	1.48e-01	2.16e-01	4.28e-01
GO:0006605 protein targeting	18	1.13e-01	-2.16e-01	3.77e-01
GO:0043923 positive regulation by host of viral transcription	12	1.96e-01	2.16e-01	4.83e-01
GO:0031072 heat shock protein binding	26	5.77e-02	2.15e-01	2.59e-01
GO:0030838 positive regulation of actin filament polymerization	26	5.84e-02	-2.14e-01	2.61e-01
GO:0097730 non-motile cilium	13	1.81e-01	-2.14e-01	4.66e-01
GO:0003712 transcription coregulator activity	76	1.24e-03	2.14e-01	2.14e-02
GO:0003723 RNA binding	372	1.54e-12	2.14e-01	3.42e-10
GO:0007020 microtubule nucleation	14	1.65e-01	2.14e-01	4.51e-01
GO:0030904 retromer complex	15	1.51e-01	-2.14e-01	4.32e-01
GO:0048008 platelet-derived growth factor receptor signaling pathway	17	1.28e-01	-2.13e-01	4.02e-01
GO:0001650 fibrillar center	101	2.16e-04	2.13e-01	5.80e-03
GO:0030513 positive regulation of BMP signaling pathway	20	9.97e-02	2.13e-01	3.49e-01
GO:0001662 behavioral fear response	12	2.02e-01	2.13e-01	4.88e-01
GO:0022904 respiratory electron transport chain	14	1.69e-01	-2.12e-01	4.54e-01
GO:0000149 SNARE binding	31	4.08e-02	-2.12e-01	2.10e-01
GO:0009611 response to wounding	20	1.00e-01	-2.12e-01	3.50e-01
GO:0051603 proteolysis involved in protein catabolic process	23	7.83e-02	-2.12e-01	3.10e-01
GO:0001708 cell fate specification	12	2.03e-01	2.12e-01	4.89e-01
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand	12	2.03e-01	-2.12e-01	4.89e-01
GO:0016236 macroautophagy	16	1.43e-01	-2.12e-01	4.21e-01
GO:0016607 nuclear speck	242	1.68e-08	2.11e-01	1.75e-06
GO:0016192 vesicle-mediated transport	101	2.59e-04	-2.11e-01	6.67e-03
GO:0010842 retina layer formation	12	2.08e-01	-2.10e-01	4.92e-01
GO:0042813 Wnt receptor activity	12	2.08e-01	-2.10e-01	4.92e-01
GO:0006376 mRNA splice site recognition	12	2.08e-01	2.10e-01	4.92e-01
GO:0001569 branching involved in blood vessel morphogenesis	15	1.60e-01	2.10e-01	4.41e-01
GO:0006338 chromatin remodeling	250	1.23e-08	2.10e-01	1.36e-06
GO:0021915 neural tube development	16	1.47e-01	2.10e-01	4.27e-01
GO:0042605 peptide antigen binding	10	2.52e-01	-2.09e-01	5.45e-01
GO:0043022 ribosome binding	46	1.42e-02	2.09e-01	1.07e-01
GO:0048146 positive regulation of fibroblast proliferation	19	1.15e-01	-2.09e-01	3.77e-01
GO:0003697 single-stranded DNA binding	67	3.13e-03	2.09e-01	4.17e-02
GO:0000460 maturation of 5.8S rRNA	11	2.32e-01	2.08e-01	5.18e-01
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis	14	1.78e-01	-2.08e-01	4.61e-01
GO:0061564 axon development	13	1.95e-01	2.08e-01	4.81e-01
GO:0060216 definitive hemopoiesis	10	2.56e-01	-2.08e-01	5.48e-01
GO:0016779 nucleotidyltransferase activity	11	2.34e-01	-2.07e-01	5.21e-01
GO:0008021 synaptic vesicle	47	1.41e-02	-2.07e-01	1.07e-01
GO:0007274 neuromuscular synaptic transmission	12	2.15e-01	2.07e-01	4.96e-01
GO:1990166 protein localization to site of double-strand break	10	2.58e-01	2.07e-01	5.50e-01
GO:0035567 non-canonical Wnt signaling pathway	13	1.97e-01	-2.07e-01	4.85e-01
GO:0005682 U5 snRNP	10	2.58e-01	2.06e-01	5.51e-01
GO:0000278 mitotic cell cycle	53	9.48e-03	2.06e-01	8.51e-02
GO:0030670 phagocytic vesicle membrane	19	1.20e-01	-2.06e-01	3.88e-01
GO:2000378 negative regulation of reactive oxygen species metabolic process	10	2.59e-01	-2.06e-01	5.52e-01
GO:1903543 positive regulation of exosomal secretion	10	2.59e-01	-2.06e-01	5.52e-01
GO:0038191 neuropilin binding	10	2.60e-01	-2.06e-01	5.52e-01
GO:0046540 U4/U6 x U5 tri-snRNP complex	23	8.76e-02	2.06e-01	3.32e-01
GO:0052689 carboxylic ester hydrolase activity	12	2.17e-01	-2.06e-01	4.99e-01
GO:0007623 circadian rhythm	18	1.33e-01	2.05e-01	4.10e-01
GO:0035249 synaptic transmission, glutamatergic	17	1.45e-01	-2.04e-01	4.24e-01
GO:0060173 limb development	23	8.98e-02	-2.04e-01	3.34e-01
GO:0048511 rhythmic process	25	7.70e-02	2.04e-01	3.07e-01
GO:0034220 monoatomic ion transmembrane transport	20	1.14e-01	-2.04e-01	3.77e-01
GO:0005777 peroxisome	48	1.46e-02	-2.04e-01	1.10e-01
GO:0046835 carbohydrate phosphorylation	20	1.15e-01	-2.03e-01	3.78e-01
GO:0001671 ATPase activator activity	18	1.36e-01	2.03e-01	4.14e-01
GO:0070300 phosphatidic acid binding	13	2.05e-01	-2.03e-01	4.90e-01
GO:0140359 ABC-type transporter activity	11	2.44e-01	-2.03e-01	5.35e-01
GO:0030216 keratinocyte differentiation	28	6.34e-02	2.03e-01	2.74e-01
GO:0006611 protein export from nucleus	22	1.00e-01	2.02e-01	3.50e-01
GO:0006891 intra-Golgi vesicle-mediated transport	18	1.37e-01	-2.02e-01	4.14e-01
GO:0034976 response to endoplasmic reticulum stress	33	4.43e-02	-2.02e-01	2.22e-01
GO:0060828 regulation of canonical Wnt signaling pathway	18	1.38e-01	-2.02e-01	4.15e-01
GO:0032024 positive regulation of insulin secretion	21	1.10e-01	-2.02e-01	3.71e-01
GO:0099523 presynaptic cytosol	11	2.47e-01	-2.02e-01	5.38e-01
GO:0050870 positive regulation of T cell activation	14	1.92e-01	-2.01e-01	4.76e-01
GO:0003824 catalytic activity	10	2.70e-01	-2.01e-01	5.64e-01
GO:0042742 defense response to bacterium	28	6.52e-02	2.01e-01	2.78e-01
GO:0005657 replication fork	20	1.19e-01	2.01e-01	3.85e-01
GO:0051393 alpha-actinin binding	10	2.71e-01	-2.01e-01	5.64e-01
GO:1904047 S-adenosyl-L-methionine binding	13	2.09e-01	2.01e-01	4.94e-01
GO:0030041 actin filament polymerization	16	1.64e-01	-2.01e-01	4.49e-01
GO:0009566 fertilization	13	2.10e-01	2.01e-01	4.94e-01
GO:0006974 DNA damage response	119	1.58e-04	2.01e-01	4.51e-03
GO:0051607 defense response to virus	55	1.01e-02	2.01e-01	8.78e-02
GO:0051082 unfolded protein binding	56	9.45e-03	2.01e-01	8.51e-02
GO:0098982 GABA-ergic synapse	28	6.67e-02	-2.00e-01	2.81e-01
GO:0031941 filamentous actin	19	1.31e-01	-2.00e-01	4.08e-01
GO:0030509 BMP signaling pathway	38	3.32e-02	-2.00e-01	1.84e-01
GO:0000387 spliceosomal snRNP assembly	17	1.54e-01	2.00e-01	4.33e-01
GO:0042789 mRNA transcription by RNA polymerase II	25	8.42e-02	2.00e-01	3.26e-01
GO:0048839 inner ear development	12	2.33e-01	1.99e-01	5.19e-01
GO:0030097 hemopoiesis	25	8.52e-02	-1.99e-01	3.28e-01
GO:0043124 negative regulation of canonical NF-kappaB signal transduction	36	3.89e-02	1.99e-01	2.06e-01
GO:0005730 nucleolus	443	1.01e-12	1.98e-01	2.98e-10
GO:0015297 antiporter activity	19	1.35e-01	-1.98e-01	4.14e-01
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	11	2.56e-01	-1.98e-01	5.48e-01
GO:0071407 cellular response to organic cyclic compound	11	2.56e-01	-1.98e-01	5.48e-01
GO:0099560 synaptic membrane adhesion	15	1.85e-01	-1.98e-01	4.70e-01
GO:0000774 adenyl-nucleotide exchange factor activity	12	2.37e-01	1.97e-01	5.25e-01
GO:0030742 GTP-dependent protein binding	13	2.19e-01	-1.97e-01	5.02e-01
GO:0097110 scaffold protein binding	28	7.16e-02	1.97e-01	2.94e-01
GO:0004896 cytokine receptor activity	18	1.49e-01	1.96e-01	4.29e-01
GO:0010839 negative regulation of keratinocyte proliferation	14	2.03e-01	-1.96e-01	4.89e-01
GO:0032588 trans-Golgi network membrane	26	8.34e-02	-1.96e-01	3.25e-01
GO:0001649 osteoblast differentiation	39	3.41e-02	-1.96e-01	1.85e-01
GO:0106222 lncRNA binding	17	1.62e-01	1.96e-01	4.44e-01
GO:0009411 response to UV	23	1.04e-01	1.96e-01	3.59e-01
GO:0003729 mRNA binding	145	4.88e-05	1.96e-01	1.66e-03
GO:0007389 pattern specification process	13	2.22e-01	-1.96e-01	5.06e-01
GO:0048701 embryonic cranial skeleton morphogenesis	13	2.22e-01	-1.95e-01	5.06e-01
GO:0030168 platelet activation	11	2.62e-01	-1.95e-01	5.54e-01
GO:0101031 protein folding chaperone complex	18	1.52e-01	1.95e-01	4.32e-01
GO:0045332 phospholipid translocation	16	1.76e-01	-1.95e-01	4.60e-01
GO:0031333 negative regulation of protein-containing complex assembly	16	1.77e-01	1.95e-01	4.60e-01
GO:0072593 reactive oxygen species metabolic process	16	1.77e-01	-1.95e-01	4.60e-01
GO:0009953 dorsal/ventral pattern formation	16	1.77e-01	-1.95e-01	4.61e-01
GO:0030198 extracellular matrix organization	79	2.88e-03	-1.94e-01	3.95e-02
GO:0006672 ceramide metabolic process	10	2.89e-01	-1.94e-01	5.85e-01
GO:0042274 ribosomal small subunit biogenesis	44	2.62e-02	1.94e-01	1.57e-01
GO:0098586 cellular response to virus	22	1.17e-01	1.93e-01	3.79e-01
GO:0034644 cellular response to UV	32	5.89e-02	1.93e-01	2.62e-01
GO:0005686 U2 snRNP	16	1.82e-01	1.93e-01	4.66e-01
GO:0006289 nucleotide-excision repair	22	1.18e-01	1.93e-01	3.82e-01
GO:0000724 double-strand break repair via homologous recombination	71	5.20e-03	1.92e-01	5.99e-02
GO:0140672 ATAC complex	11	2.71e-01	1.92e-01	5.64e-01
GO:0072089 stem cell proliferation	21	1.29e-01	-1.92e-01	4.04e-01
GO:0006606 protein import into nucleus	62	9.17e-03	1.91e-01	8.51e-02
GO:0050919 negative chemotaxis	22	1.21e-01	-1.91e-01	3.90e-01
GO:0051726 regulation of cell cycle	104	7.88e-04	1.91e-01	1.57e-02
GO:0019216 regulation of lipid metabolic process	10	2.96e-01	-1.91e-01	5.96e-01
GO:0016787 hydrolase activity	108	6.58e-04	1.90e-01	1.37e-02
GO:0000045 autophagosome assembly	52	1.80e-02	-1.90e-01	1.27e-01
GO:0008333 endosome to lysosome transport	32	6.36e-02	-1.90e-01	2.74e-01
GO:0045724 positive regulation of cilium assembly	13	2.37e-01	1.89e-01	5.26e-01
GO:0031965 nuclear membrane	121	3.30e-04	1.89e-01	8.12e-03
GO:0034067 protein localization to Golgi apparatus	13	2.38e-01	1.89e-01	5.27e-01
GO:0098761 cellular response to interleukin-7	10	3.01e-01	-1.89e-01	6.01e-01
GO:0046488 phosphatidylinositol metabolic process	13	2.39e-01	1.89e-01	5.28e-01
GO:0006865 amino acid transport	11	2.79e-01	1.89e-01	5.73e-01
GO:0072344 rescue of stalled ribosome	26	9.63e-02	1.88e-01	3.45e-01
GO:1904646 cellular response to amyloid-beta	10	3.05e-01	-1.87e-01	6.03e-01
GO:0032008 positive regulation of TOR signaling	12	2.62e-01	-1.87e-01	5.54e-01
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane	18	1.70e-01	-1.87e-01	4.55e-01
GO:0000381 regulation of alternative mRNA splicing, via spliceosome	31	7.18e-02	1.87e-01	2.94e-01
GO:0005109 frizzled binding	18	1.70e-01	-1.87e-01	4.55e-01
GO:0006366 transcription by RNA polymerase II	73	5.86e-03	1.87e-01	6.62e-02
GO:0097352 autophagosome maturation	23	1.22e-01	-1.86e-01	3.91e-01
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle	14	2.28e-01	1.86e-01	5.14e-01
GO:0048786 presynaptic active zone	10	3.09e-01	-1.86e-01	6.05e-01
GO:0060349 bone morphogenesis	11	2.87e-01	1.85e-01	5.83e-01
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	16	2.00e-01	-1.85e-01	4.85e-01
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle	24	1.16e-01	-1.85e-01	3.79e-01
GO:0001958 endochondral ossification	15	2.15e-01	-1.85e-01	4.96e-01
GO:0031681 G-protein beta-subunit binding	10	3.14e-01	-1.84e-01	6.10e-01
GO:0043484 regulation of RNA splicing	23	1.27e-01	1.84e-01	4.02e-01
GO:0030017 sarcomere	12	2.70e-01	-1.84e-01	5.64e-01
GO:0042752 regulation of circadian rhythm	27	9.85e-02	1.84e-01	3.47e-01
GO:0001516 prostaglandin biosynthetic process	10	3.15e-01	1.84e-01	6.12e-01
GO:0035064 methylated histone binding	42	4.02e-02	1.83e-01	2.09e-01
GO:0060339 negative regulation of type I interferon-mediated signaling pathway	13	2.54e-01	1.83e-01	5.48e-01
GO:0030286 dynein complex	10	3.18e-01	-1.82e-01	6.16e-01
GO:0016605 PML body	61	1.38e-02	1.82e-01	1.06e-01
GO:0002682 regulation of immune system process	10	3.18e-01	-1.82e-01	6.16e-01
GO:0017022 myosin binding	11	2.95e-01	-1.82e-01	5.94e-01
GO:0000775 chromosome, centromeric region	31	7.95e-02	1.82e-01	3.13e-01
GO:0000791 euchromatin	29	9.00e-02	1.82e-01	3.34e-01
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding	41	4.41e-02	-1.82e-01	2.22e-01
GO:0009966 regulation of signal transduction	39	4.98e-02	1.82e-01	2.39e-01
GO:0045595 regulation of cell differentiation	13	2.57e-01	-1.81e-01	5.50e-01
GO:0006893 Golgi to plasma membrane transport	19	1.71e-01	1.81e-01	4.55e-01
GO:0035098 ESC/E(Z) complex	12	2.77e-01	1.81e-01	5.72e-01
GO:0086091 regulation of heart rate by cardiac conduction	20	1.61e-01	1.81e-01	4.42e-01
GO:0016604 nuclear body	173	4.09e-05	1.81e-01	1.42e-03
GO:0001947 heart looping	23	1.33e-01	1.81e-01	4.11e-01
GO:0097602 cullin family protein binding	16	2.10e-01	-1.81e-01	4.94e-01
GO:0030326 embryonic limb morphogenesis	14	2.43e-01	-1.80e-01	5.33e-01
GO:0003925 G protein activity	18	1.86e-01	-1.80e-01	4.72e-01
GO:0019933 cAMP-mediated signaling	13	2.62e-01	-1.80e-01	5.54e-01
GO:0043679 axon terminus	17	1.99e-01	1.80e-01	4.85e-01
GO:0071168 protein localization to chromatin	17	2.00e-01	1.80e-01	4.85e-01
GO:0001541 ovarian follicle development	19	1.76e-01	1.79e-01	4.60e-01
GO:0070063 RNA polymerase binding	12	2.83e-01	1.79e-01	5.77e-01
GO:0051085 chaperone cofactor-dependent protein refolding	23	1.37e-01	1.79e-01	4.14e-01
GO:0060070 canonical Wnt signaling pathway	58	1.86e-02	-1.79e-01	1.30e-01
GO:0042169 SH2 domain binding	20	1.66e-01	1.79e-01	4.53e-01
GO:0001938 positive regulation of endothelial cell proliferation	23	1.39e-01	-1.78e-01	4.16e-01
GO:0007064 mitotic sister chromatid cohesion	10	3.29e-01	1.78e-01	6.25e-01
GO:0048278 vesicle docking	13	2.66e-01	-1.78e-01	5.59e-01
GO:0019882 antigen processing and presentation	11	3.06e-01	-1.78e-01	6.03e-01
GO:0032211 negative regulation of telomere maintenance via telomerase	10	3.30e-01	1.78e-01	6.25e-01
GO:0006261 DNA-templated DNA replication	18	1.92e-01	1.78e-01	4.76e-01
GO:0051480 regulation of cytosolic calcium ion concentration	13	2.68e-01	-1.77e-01	5.61e-01
GO:0005681 spliceosomal complex	43	4.50e-02	1.77e-01	2.24e-01
GO:0007204 positive regulation of cytosolic calcium ion concentration	19	1.83e-01	-1.76e-01	4.67e-01
GO:0030500 regulation of bone mineralization	12	2.90e-01	-1.76e-01	5.86e-01
GO:0045600 positive regulation of fat cell differentiation	21	1.63e-01	-1.76e-01	4.47e-01
GO:0005759 mitochondrial matrix	119	9.42e-04	-1.76e-01	1.79e-02
GO:0072686 mitotic spindle	69	1.16e-02	1.76e-01	9.47e-02
GO:0007059 chromosome segregation	41	5.21e-02	1.75e-01	2.45e-01
GO:0050681 nuclear androgen receptor binding	16	2.27e-01	1.75e-01	5.13e-01
GO:0006879 intracellular iron ion homeostasis	31	9.40e-02	-1.74e-01	3.38e-01
GO:0008253 5’-nucleotidase activity	10	3.42e-01	-1.74e-01	6.35e-01
GO:0070536 protein K63-linked deubiquitination	16	2.30e-01	1.73e-01	5.15e-01
GO:0000407 phagophore assembly site	20	1.80e-01	-1.73e-01	4.64e-01
GO:0030140 trans-Golgi network transport vesicle	11	3.20e-01	-1.73e-01	6.18e-01
GO:0035979 histone H2AXS139 kinase activity	32	9.04e-02	1.73e-01	3.34e-01
GO:0030331 nuclear estrogen receptor binding	19	1.92e-01	1.73e-01	4.76e-01
GO:0000932 P-body	60	2.10e-02	1.72e-01	1.40e-01
GO:0061952 midbody abscission	14	2.66e-01	-1.72e-01	5.59e-01
GO:0015485 cholesterol binding	29	1.11e-01	-1.71e-01	3.74e-01
GO:0035035 histone acetyltransferase binding	12	3.07e-01	1.70e-01	6.03e-01
GO:0006310 DNA recombination	23	1.59e-01	1.70e-01	4.41e-01
GO:0001702 gastrulation with mouth forming second	10	3.54e-01	-1.69e-01	6.49e-01
GO:0120009 intermembrane lipid transfer	16	2.42e-01	-1.69e-01	5.31e-01
GO:0034063 stress granule assembly	20	1.91e-01	1.69e-01	4.75e-01
GO:0005765 lysosomal membrane	138	6.42e-04	-1.69e-01	1.37e-02
GO:0046875 ephrin receptor binding	17	2.29e-01	1.68e-01	5.14e-01
GO:0008180 COP9 signalosome	21	1.82e-01	1.68e-01	4.66e-01
GO:0019915 lipid storage	11	3.34e-01	-1.68e-01	6.28e-01
GO:0030833 regulation of actin filament polymerization	21	1.83e-01	-1.68e-01	4.67e-01
GO:0060586 multicellular organismal-level iron ion homeostasis	14	2.77e-01	-1.68e-01	5.72e-01
GO:0008092 cytoskeletal protein binding	16	2.47e-01	-1.67e-01	5.38e-01
GO:2000352 negative regulation of endothelial cell apoptotic process	14	2.79e-01	1.67e-01	5.73e-01
GO:0031966 mitochondrial membrane	39	7.14e-02	-1.67e-01	2.94e-01
GO:0007010 cytoskeleton organization	51	4.00e-02	1.66e-01	2.09e-01
GO:0080008 Cul4-RING E3 ubiquitin ligase complex	13	2.99e-01	1.66e-01	6.00e-01
GO:0060325 face morphogenesis	21	1.87e-01	-1.66e-01	4.73e-01
GO:0043588 skin development	24	1.59e-01	-1.66e-01	4.41e-01
GO:0005815 microtubule organizing center	36	8.56e-02	1.66e-01	3.28e-01
GO:0017148 negative regulation of translation	43	6.05e-02	1.65e-01	2.66e-01
GO:0016342 catenin complex	13	3.03e-01	-1.65e-01	6.03e-01
GO:0006096 glycolytic process	23	1.71e-01	-1.65e-01	4.55e-01
GO:0030593 neutrophil chemotaxis	13	3.04e-01	-1.65e-01	6.03e-01
GO:1903076 regulation of protein localization to plasma membrane	18	2.27e-01	-1.65e-01	5.13e-01
GO:0033077 T cell differentiation in thymus	17	2.41e-01	-1.64e-01	5.31e-01
GO:0003743 translation initiation factor activity	39	7.62e-02	1.64e-01	3.05e-01
GO:0007018 microtubule-based movement	40	7.29e-02	1.64e-01	2.96e-01
GO:0007097 nuclear migration	15	2.72e-01	1.64e-01	5.65e-01
GO:0070050 neuron cellular homeostasis	14	2.90e-01	1.63e-01	5.86e-01
GO:0001736 establishment of planar polarity	12	3.27e-01	-1.63e-01	6.24e-01
GO:0061608 nuclear import signal receptor activity	14	2.90e-01	1.63e-01	5.86e-01
GO:0042100 B cell proliferation	14	2.91e-01	1.63e-01	5.86e-01
GO:0000307 cyclin-dependent protein kinase holoenzyme complex	20	2.08e-01	-1.63e-01	4.92e-01
GO:0035861 site of double-strand break	58	3.25e-02	1.62e-01	1.82e-01
GO:0048255 mRNA stabilization	16	2.61e-01	1.62e-01	5.54e-01
GO:0007179 transforming growth factor beta receptor signaling pathway	48	5.19e-02	-1.62e-01	2.45e-01
GO:0017124 SH3 domain binding	43	6.58e-02	-1.62e-01	2.79e-01
GO:0030010 establishment of cell polarity	19	2.22e-01	-1.62e-01	5.06e-01
GO:0048813 dendrite morphogenesis	21	2.00e-01	-1.62e-01	4.85e-01
GO:0004879 nuclear receptor activity	38	8.56e-02	-1.61e-01	3.28e-01
GO:0043995 histone H4K5 acetyltransferase activity	10	3.77e-01	1.61e-01	6.61e-01
GO:0043996 histone H4K8 acetyltransferase activity	10	3.77e-01	1.61e-01	6.61e-01
GO:0045505 dynein intermediate chain binding	17	2.51e-01	-1.61e-01	5.43e-01
GO:0048705 skeletal system morphogenesis	15	2.81e-01	-1.61e-01	5.74e-01
GO:0005882 intermediate filament	21	2.02e-01	1.61e-01	4.88e-01
GO:0030672 synaptic vesicle membrane	44	6.53e-02	-1.61e-01	2.78e-01
GO:0035023 regulation of Rho protein signal transduction	16	2.67e-01	-1.60e-01	5.60e-01
GO:0006487 protein N-linked glycosylation	29	1.36e-01	-1.60e-01	4.14e-01
GO:0007368 determination of left/right symmetry	28	1.43e-01	-1.60e-01	4.21e-01
GO:0120020 cholesterol transfer activity	13	3.19e-01	-1.60e-01	6.17e-01
GO:0016853 isomerase activity	19	2.29e-01	1.59e-01	5.14e-01
GO:0007098 centrosome cycle	17	2.55e-01	1.59e-01	5.48e-01
GO:0005576 extracellular region	242	2.15e-05	-1.59e-01	8.10e-04
GO:0001501 skeletal system development	33	1.15e-01	-1.59e-01	3.77e-01
GO:0008089 anterograde axonal transport	10	3.86e-01	-1.58e-01	6.69e-01
GO:0008143 poly(A) binding	13	3.24e-01	1.58e-01	6.22e-01
GO:0006914 autophagy	44	7.01e-02	-1.58e-01	2.90e-01
GO:0031514 motile cilium	38	9.24e-02	-1.58e-01	3.37e-01
GO:0005881 cytoplasmic microtubule	30	1.38e-01	1.57e-01	4.14e-01
GO:0005871 kinesin complex	22	2.04e-01	1.56e-01	4.90e-01
GO:0030139 endocytic vesicle	38	9.67e-02	1.56e-01	3.45e-01
GO:0000712 resolution of meiotic recombination intermediates	14	3.13e-01	1.56e-01	6.10e-01
GO:1900182 positive regulation of protein localization to nucleus	25	1.78e-01	1.56e-01	4.61e-01
GO:0004677 DNA-dependent protein kinase activity	31	1.34e-01	1.55e-01	4.14e-01
GO:0050768 negative regulation of neurogenesis	10	3.97e-01	-1.55e-01	6.77e-01
GO:0005385 zinc ion transmembrane transporter activity	15	3.00e-01	-1.55e-01	6.00e-01
GO:1901981 phosphatidylinositol phosphate binding	15	3.00e-01	-1.54e-01	6.00e-01
GO:0060090 molecular adaptor activity	75	2.09e-02	-1.54e-01	1.40e-01
GO:0042127 regulation of cell population proliferation	44	7.66e-02	1.54e-01	3.06e-01
GO:0071560 cellular response to transforming growth factor beta stimulus	17	2.72e-01	1.54e-01	5.65e-01
GO:0046677 response to antibiotic	13	3.37e-01	1.54e-01	6.30e-01
GO:0031468 nuclear membrane reassembly	11	3.77e-01	-1.54e-01	6.61e-01
GO:0016055 Wnt signaling pathway	77	2.02e-02	-1.53e-01	1.37e-01
GO:0033017 sarcoplasmic reticulum membrane	10	4.02e-01	-1.53e-01	6.83e-01
GO:0001664 G protein-coupled receptor binding	22	2.18e-01	1.52e-01	4.99e-01
GO:0000070 mitotic sister chromatid segregation	18	2.65e-01	1.52e-01	5.58e-01
GO:0072518 Rho-dependent protein serine/threonine kinase activity	32	1.39e-01	1.51e-01	4.16e-01
GO:0070840 dynein complex binding	12	3.65e-01	1.51e-01	6.53e-01
GO:0004676 3-phosphoinositide-dependent protein kinase activity	31	1.46e-01	1.51e-01	4.27e-01
GO:0005758 mitochondrial intermembrane space	47	7.40e-02	-1.51e-01	2.99e-01
GO:0012507 ER to Golgi transport vesicle membrane	11	3.87e-01	1.51e-01	6.69e-01
GO:0003151 outflow tract morphogenesis	19	2.56e-01	1.51e-01	5.48e-01
GO:0044782 cilium organization	13	3.48e-01	1.50e-01	6.43e-01
GO:0031663 lipopolysaccharide-mediated signaling pathway	10	4.10e-01	-1.50e-01	6.92e-01
GO:0006644 phospholipid metabolic process	11	3.88e-01	-1.50e-01	6.69e-01
GO:0001657 ureteric bud development	14	3.31e-01	1.50e-01	6.25e-01
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II	12	3.68e-01	-1.50e-01	6.55e-01
GO:0038066 p38MAPK cascade	12	3.68e-01	1.50e-01	6.55e-01
GO:0005788 endoplasmic reticulum lumen	40	1.01e-01	-1.50e-01	3.51e-01
GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity	34	1.31e-01	1.50e-01	4.08e-01
GO:0022857 transmembrane transporter activity	42	9.36e-02	-1.50e-01	3.38e-01
GO:0035175 histone H3S10 kinase activity	31	1.50e-01	1.50e-01	4.29e-01
GO:0072354 histone H3T3 kinase activity	31	1.50e-01	1.50e-01	4.29e-01
GO:1904262 negative regulation of TORC1 signaling	28	1.72e-01	1.49e-01	4.57e-01
GO:0004693 cyclin-dependent protein serine/threonine kinase activity	10	4.16e-01	1.49e-01	6.93e-01
GO:0090110 COPII-coated vesicle cargo loading	10	4.17e-01	-1.48e-01	6.93e-01
GO:0030316 osteoclast differentiation	29	1.67e-01	1.48e-01	4.53e-01
GO:0001819 positive regulation of cytokine production	13	3.55e-01	-1.48e-01	6.49e-01
GO:0051123 RNA polymerase II preinitiation complex assembly	16	3.05e-01	-1.48e-01	6.03e-01
GO:0006884 cell volume homeostasis	13	3.57e-01	-1.48e-01	6.50e-01
GO:0048812 neuron projection morphogenesis	32	1.49e-01	1.48e-01	4.29e-01
GO:0008283 cell population proliferation	65	4.04e-02	1.47e-01	2.10e-01
GO:0032924 activin receptor signaling pathway	12	3.78e-01	-1.47e-01	6.62e-01
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage	24	2.15e-01	1.46e-01	4.96e-01
GO:0007040 lysosome organization	33	1.46e-01	-1.46e-01	4.27e-01
GO:0031463 Cul3-RING ubiquitin ligase complex	41	1.05e-01	-1.46e-01	3.62e-01
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process	43	9.79e-02	-1.46e-01	3.47e-01
GO:0045668 negative regulation of osteoblast differentiation	27	1.90e-01	-1.46e-01	4.75e-01
GO:0090316 positive regulation of intracellular protein transport	14	3.46e-01	1.45e-01	6.41e-01
GO:0042552 myelination	28	1.83e-01	-1.45e-01	4.67e-01
GO:0017018 myosin phosphatase activity	13	3.65e-01	-1.45e-01	6.53e-01
GO:0140791 histone H2AXS140 phosphatase activity	13	3.65e-01	-1.45e-01	6.53e-01
GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	13	3.65e-01	-1.45e-01	6.53e-01
GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	13	3.65e-01	-1.45e-01	6.53e-01
GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	13	3.65e-01	-1.45e-01	6.53e-01
GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	13	3.65e-01	-1.45e-01	6.53e-01
GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	13	3.65e-01	-1.45e-01	6.53e-01
GO:1990439 MAP kinase serine/threonine phosphatase activity	13	3.65e-01	-1.45e-01	6.53e-01
GO:0031901 early endosome membrane	76	2.89e-02	-1.45e-01	1.66e-01
GO:0060261 positive regulation of transcription initiation by RNA polymerase II	30	1.71e-01	1.45e-01	4.55e-01
GO:0008305 integrin complex	17	3.03e-01	-1.44e-01	6.03e-01
GO:0045202 synapse	165	1.40e-03	-1.44e-01	2.32e-02
GO:0033173 calcineurin-NFAT signaling cascade	10	4.29e-01	-1.44e-01	7.01e-01
GO:0061025 membrane fusion	21	2.53e-01	-1.44e-01	5.47e-01
GO:0042826 histone deacetylase binding	66	4.32e-02	1.44e-01	2.19e-01
GO:0005507 copper ion binding	24	2.22e-01	-1.44e-01	5.06e-01
GO:0001503 ossification	26	2.05e-01	-1.44e-01	4.90e-01
GO:0007005 mitochondrion organization	61	5.28e-02	-1.43e-01	2.48e-01
GO:0021549 cerebellum development	10	4.32e-01	-1.43e-01	7.03e-01
GO:0061436 establishment of skin barrier	13	3.71e-01	1.43e-01	6.58e-01
GO:0006506 GPI anchor biosynthetic process	25	2.15e-01	-1.43e-01	4.96e-01
GO:0048013 ephrin receptor signaling pathway	26	2.07e-01	1.43e-01	4.92e-01
GO:2000773 negative regulation of cellular senescence	12	3.91e-01	-1.43e-01	6.72e-01
GO:0060612 adipose tissue development	23	2.36e-01	-1.43e-01	5.24e-01
GO:0034332 adherens junction organization	12	3.92e-01	-1.43e-01	6.72e-01
GO:0008203 cholesterol metabolic process	31	1.69e-01	1.43e-01	4.54e-01
GO:0000132 establishment of mitotic spindle orientation	26	2.08e-01	1.43e-01	4.92e-01
GO:0051491 positive regulation of filopodium assembly	15	3.40e-01	1.42e-01	6.33e-01
GO:0032456 endocytic recycling	42	1.11e-01	-1.42e-01	3.73e-01
GO:0000902 cell morphogenesis	55	6.83e-02	-1.42e-01	2.85e-01
GO:0009887 animal organ morphogenesis	34	1.52e-01	1.42e-01	4.33e-01
GO:0006935 chemotaxis	14	3.58e-01	-1.42e-01	6.50e-01
GO:0044291 cell-cell contact zone	12	3.95e-01	-1.42e-01	6.76e-01
GO:0007229 integrin-mediated signaling pathway	43	1.08e-01	-1.42e-01	3.67e-01
GO:0019902 phosphatase binding	22	2.52e-01	1.41e-01	5.45e-01
GO:0070402 NADPH binding	10	4.40e-01	-1.41e-01	7.07e-01
GO:0032874 positive regulation of stress-activated MAPK cascade	11	4.18e-01	1.41e-01	6.93e-01
GO:0005667 transcription regulator complex	91	2.02e-02	1.41e-01	1.37e-01
GO:0071277 cellular response to calcium ion	32	1.67e-01	-1.41e-01	4.53e-01
GO:0008047 enzyme activator activity	15	3.45e-01	1.41e-01	6.40e-01
GO:0045666 positive regulation of neuron differentiation	26	2.14e-01	1.41e-01	4.96e-01
GO:0007160 cell-matrix adhesion	40	1.25e-01	-1.40e-01	3.96e-01
GO:0061136 regulation of proteasomal protein catabolic process	11	4.20e-01	1.40e-01	6.97e-01
GO:0043525 positive regulation of neuron apoptotic process	18	3.04e-01	1.40e-01	6.03e-01
GO:0019003 GDP binding	44	1.08e-01	-1.40e-01	3.67e-01
GO:0005685 U1 snRNP	12	4.02e-01	1.40e-01	6.83e-01
GO:0001772 immunological synapse	23	2.47e-01	-1.40e-01	5.38e-01
GO:0006488 dolichol-linked oligosaccharide biosynthetic process	14	3.66e-01	-1.40e-01	6.54e-01
GO:0019005 SCF ubiquitin ligase complex	43	1.14e-01	-1.39e-01	3.77e-01
GO:0004715 non-membrane spanning protein tyrosine kinase activity	20	2.81e-01	1.39e-01	5.74e-01
GO:0034198 cellular response to amino acid starvation	31	1.80e-01	1.39e-01	4.64e-01
GO:2000114 regulation of establishment of cell polarity	10	4.46e-01	1.39e-01	7.12e-01
GO:0010575 positive regulation of vascular endothelial growth factor production	13	3.85e-01	1.39e-01	6.68e-01
GO:0006351 DNA-templated transcription	36	1.49e-01	1.39e-01	4.29e-01
GO:0034614 cellular response to reactive oxygen species	16	3.36e-01	-1.39e-01	6.30e-01
GO:0031647 regulation of protein stability	57	6.98e-02	1.39e-01	2.90e-01
GO:0008360 regulation of cell shape	61	6.09e-02	1.39e-01	2.67e-01
GO:0051642 centrosome localization	13	3.86e-01	1.39e-01	6.69e-01
GO:0000146 microfilament motor activity	20	2.83e-01	-1.39e-01	5.77e-01
GO:0030308 negative regulation of cell growth	42	1.23e-01	-1.38e-01	3.93e-01
GO:0030992 intraciliary transport particle B	15	3.56e-01	-1.38e-01	6.49e-01
GO:0048821 erythrocyte development	14	3.73e-01	1.37e-01	6.59e-01
GO:0005249 voltage-gated potassium channel activity	15	3.58e-01	1.37e-01	6.50e-01
GO:0030878 thyroid gland development	14	3.74e-01	-1.37e-01	6.59e-01
GO:0030057 desmosome	12	4.11e-01	1.37e-01	6.92e-01
GO:0048854 brain morphogenesis	14	3.75e-01	1.37e-01	6.59e-01
GO:0006887 exocytosis	44	1.16e-01	-1.37e-01	3.79e-01
GO:0031369 translation initiation factor binding	12	4.12e-01	1.37e-01	6.93e-01
GO:0001223 transcription coactivator binding	21	2.79e-01	1.37e-01	5.73e-01
GO:1990244 histone H2AT120 kinase activity	31	1.89e-01	1.36e-01	4.74e-01
GO:0005903 brush border	19	3.05e-01	-1.36e-01	6.03e-01
GO:0051287 NAD binding	19	3.05e-01	-1.36e-01	6.03e-01
GO:0071577 zinc ion transmembrane transport	10	4.58e-01	-1.35e-01	7.24e-01
GO:0046513 ceramide biosynthetic process	19	3.09e-01	1.35e-01	6.05e-01
GO:0061351 neural precursor cell proliferation	15	3.67e-01	-1.35e-01	6.55e-01
GO:0042995 cell projection	55	8.48e-02	-1.34e-01	3.27e-01
GO:0042572 retinol metabolic process	13	4.02e-01	-1.34e-01	6.83e-01
GO:0030276 clathrin binding	17	3.40e-01	1.34e-01	6.33e-01
GO:0006886 intracellular protein transport	161	3.60e-03	-1.33e-01	4.59e-02
GO:0071782 endoplasmic reticulum tubular network	12	4.24e-01	1.33e-01	6.99e-01
GO:0035176 social behavior	16	3.58e-01	-1.33e-01	6.50e-01
GO:0051496 positive regulation of stress fiber assembly	31	2.01e-01	-1.33e-01	4.87e-01
GO:0030030 cell projection organization	13	4.09e-01	1.32e-01	6.91e-01
GO:0051497 negative regulation of stress fiber assembly	18	3.31e-01	-1.32e-01	6.25e-01
GO:0070979 protein K11-linked ubiquitination	22	2.83e-01	1.32e-01	5.77e-01
GO:0006368 transcription elongation by RNA polymerase II	24	2.64e-01	1.32e-01	5.56e-01
GO:0034097 response to cytokine	12	4.30e-01	-1.32e-01	7.01e-01
GO:0035402 histone H3T11 kinase activity	30	2.15e-01	1.31e-01	4.96e-01
GO:0044022 histone H3S28 kinase activity	30	2.15e-01	1.31e-01	4.96e-01
GO:0044023 histone H4S1 kinase activity	30	2.15e-01	1.31e-01	4.96e-01
GO:0044024 histone H2AS1 kinase activity	30	2.15e-01	1.31e-01	4.96e-01
GO:0044025 histone H2BS14 kinase activity	30	2.15e-01	1.31e-01	4.96e-01
GO:0072371 histone H2AS121 kinase activity	30	2.15e-01	1.31e-01	4.96e-01
GO:0140855 histone H3S57 kinase activity	30	2.15e-01	1.31e-01	4.96e-01
GO:0140857 histone H3T45 kinase activity	30	2.15e-01	1.31e-01	4.96e-01
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	17	3.52e-01	1.31e-01	6.46e-01
GO:0045785 positive regulation of cell adhesion	15	3.82e-01	-1.30e-01	6.66e-01
GO:0006730 one-carbon metabolic process	13	4.16e-01	1.30e-01	6.93e-01
GO:0042981 regulation of apoptotic process	55	9.64e-02	1.30e-01	3.45e-01
GO:0000159 protein phosphatase type 2A complex	12	4.38e-01	1.29e-01	7.07e-01
GO:0051260 protein homooligomerization	46	1.30e-01	1.29e-01	4.06e-01
GO:0016925 protein sumoylation	19	3.30e-01	1.29e-01	6.25e-01
GO:0051289 protein homotetramerization	34	1.93e-01	1.29e-01	4.77e-01
GO:0005930 axoneme	47	1.26e-01	-1.29e-01	4.00e-01
GO:0002224 toll-like receptor signaling pathway	14	4.04e-01	1.29e-01	6.84e-01
GO:0090575 RNA polymerase II transcription regulator complex	53	1.05e-01	1.29e-01	3.62e-01
GO:0006457 protein folding	81	4.54e-02	1.29e-01	2.25e-01
GO:0007612 learning	13	4.22e-01	1.29e-01	6.98e-01
GO:0001778 plasma membrane repair	16	3.73e-01	-1.29e-01	6.59e-01
GO:0015031 protein transport	174	3.53e-03	-1.28e-01	4.53e-02
GO:0014069 postsynaptic density	97	2.91e-02	-1.28e-01	1.67e-01
GO:0071007 U2-type catalytic step 2 spliceosome	24	2.77e-01	1.28e-01	5.72e-01
GO:0006303 double-strand break repair via nonhomologous end joining	20	3.23e-01	1.28e-01	6.20e-01
GO:0032481 positive regulation of type I interferon production	18	3.49e-01	1.28e-01	6.43e-01
GO:0005654 nucleoplasm	1532	2.95e-16	1.27e-01	2.62e-13
GO:0006468 protein phosphorylation	12	4.46e-01	-1.27e-01	7.12e-01
GO:0034450 ubiquitin-ubiquitin ligase activity	12	4.46e-01	-1.27e-01	7.12e-01
GO:0071456 cellular response to hypoxia	33	2.07e-01	-1.27e-01	4.92e-01
GO:0032259 methylation	76	5.62e-02	1.27e-01	2.57e-01
GO:0048144 fibroblast proliferation	22	3.04e-01	-1.27e-01	6.03e-01
GO:0032570 response to progesterone	13	4.30e-01	1.26e-01	7.01e-01
GO:0008361 regulation of cell size	13	4.31e-01	-1.26e-01	7.02e-01
GO:0005102 signaling receptor binding	81	5.02e-02	-1.26e-01	2.39e-01
GO:0043488 regulation of mRNA stability	16	3.84e-01	1.26e-01	6.67e-01
GO:0008584 male gonad development	28	2.50e-01	-1.26e-01	5.43e-01
GO:0071333 cellular response to glucose stimulus	13	4.35e-01	-1.25e-01	7.05e-01
GO:0043409 negative regulation of MAPK cascade	20	3.33e-01	1.25e-01	6.27e-01
GO:0008543 fibroblast growth factor receptor signaling pathway	37	1.88e-01	-1.25e-01	4.74e-01
GO:0045121 membrane raft	76	5.99e-02	-1.25e-01	2.63e-01
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway	13	4.35e-01	1.25e-01	7.05e-01
GO:0043015 gamma-tubulin binding	21	3.22e-01	1.25e-01	6.19e-01
GO:0045740 positive regulation of DNA replication	11	4.74e-01	1.25e-01	7.38e-01
GO:0045444 fat cell differentiation	44	1.53e-01	-1.25e-01	4.33e-01
GO:0022008 neurogenesis	31	2.32e-01	1.24e-01	5.18e-01
GO:0002053 positive regulation of mesenchymal cell proliferation	11	4.76e-01	-1.24e-01	7.41e-01
GO:0001658 branching involved in ureteric bud morphogenesis	18	3.62e-01	-1.24e-01	6.53e-01
GO:0140823 histone H2BS36 kinase activity	31	2.33e-01	1.24e-01	5.19e-01
GO:0045109 intermediate filament organization	10	4.98e-01	-1.24e-01	7.59e-01
GO:0006874 intracellular calcium ion homeostasis	38	1.87e-01	1.24e-01	4.73e-01
GO:0006783 heme biosynthetic process	10	5.00e-01	-1.23e-01	7.59e-01
GO:0005874 microtubule	131	1.50e-02	1.23e-01	1.11e-01
GO:0120163 negative regulation of cold-induced thermogenesis	21	3.29e-01	1.23e-01	6.24e-01
GO:0150052 regulation of postsynapse assembly	13	4.42e-01	1.23e-01	7.09e-01
GO:0004679 AMP-activated protein kinase activity	32	2.29e-01	1.23e-01	5.14e-01
GO:0051865 protein autoubiquitination	38	1.91e-01	1.23e-01	4.75e-01
GO:0070971 endoplasmic reticulum exit site	19	3.55e-01	-1.23e-01	6.49e-01
GO:0031290 retinal ganglion cell axon guidance	12	4.62e-01	-1.23e-01	7.27e-01
GO:0061157 mRNA destabilization	12	4.63e-01	1.22e-01	7.27e-01
GO:0000794 condensed nuclear chromosome	20	3.44e-01	1.22e-01	6.40e-01
GO:0042645 mitochondrial nucleoid	37	1.99e-01	1.22e-01	4.85e-01
GO:0001675 acrosome assembly	11	4.83e-01	-1.22e-01	7.46e-01
GO:0005868 cytoplasmic dynein complex	14	4.29e-01	-1.22e-01	7.01e-01
GO:0032993 protein-DNA complex	21	3.34e-01	1.22e-01	6.28e-01
GO:0071300 cellular response to retinoic acid	18	3.72e-01	-1.22e-01	6.58e-01
GO:0008017 microtubule binding	153	9.59e-03	1.22e-01	8.53e-02
GO:0055085 transmembrane transport	88	4.98e-02	-1.21e-01	2.39e-01
GO:0005975 carbohydrate metabolic process	49	1.43e-01	-1.21e-01	4.21e-01
GO:0045499 chemorepellent activity	20	3.50e-01	-1.21e-01	6.44e-01
GO:0007080 mitotic metaphase chromosome alignment	23	3.16e-01	-1.21e-01	6.14e-01
GO:0016757 glycosyltransferase activity	14	4.34e-01	1.21e-01	7.05e-01
GO:0003676 nucleic acid binding	106	3.22e-02	1.21e-01	1.81e-01
GO:0009968 negative regulation of signal transduction	14	4.36e-01	1.20e-01	7.06e-01
GO:0005154 epidermal growth factor receptor binding	19	3.65e-01	-1.20e-01	6.53e-01
GO:0045111 intermediate filament cytoskeleton	23	3.19e-01	-1.20e-01	6.17e-01
GO:0006465 signal peptide processing	10	5.12e-01	1.20e-01	7.72e-01
GO:0051010 microtubule plus-end binding	11	4.92e-01	1.20e-01	7.53e-01
GO:0030658 transport vesicle membrane	13	4.58e-01	-1.19e-01	7.24e-01
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity	15	4.25e-01	-1.19e-01	6.99e-01
GO:0010719 negative regulation of epithelial to mesenchymal transition	16	4.10e-01	-1.19e-01	6.92e-01
GO:0048872 homeostasis of number of cells	14	4.42e-01	1.19e-01	7.09e-01
GO:0051015 actin filament binding	121	2.43e-02	-1.19e-01	1.51e-01
GO:0048787 presynaptic active zone membrane	10	5.16e-01	1.19e-01	7.76e-01
GO:0001935 endothelial cell proliferation	12	4.77e-01	-1.19e-01	7.41e-01
GO:0048873 homeostasis of number of cells within a tissue	15	4.27e-01	1.18e-01	7.01e-01
GO:0004711 ribosomal protein S6 kinase activity	32	2.47e-01	1.18e-01	5.38e-01
GO:0030970 retrograde protein transport, ER to cytosol	12	4.79e-01	1.18e-01	7.42e-01
GO:0004842 ubiquitin-protein transferase activity	65	1.00e-01	1.18e-01	3.49e-01
GO:0043021 ribonucleoprotein complex binding	23	3.28e-01	1.18e-01	6.24e-01
GO:0055088 lipid homeostasis	19	3.74e-01	-1.18e-01	6.59e-01
GO:0042407 cristae formation	11	4.99e-01	1.18e-01	7.59e-01
GO:0005540 hyaluronic acid binding	13	4.63e-01	1.18e-01	7.27e-01
GO:1990830 cellular response to leukemia inhibitory factor	66	9.89e-02	1.18e-01	3.48e-01
GO:0007416 synapse assembly	25	3.10e-01	1.17e-01	6.05e-01
GO:0071233 cellular response to L-leucine	10	5.20e-01	1.17e-01	7.79e-01
GO:0001725 stress fiber	42	1.90e-01	-1.17e-01	4.75e-01
GO:0072542 protein phosphatase activator activity	10	5.23e-01	1.17e-01	7.81e-01
GO:0032012 regulation of ARF protein signal transduction	14	4.50e-01	-1.17e-01	7.16e-01
GO:0044877 protein-containing complex binding	104	4.02e-02	1.17e-01	2.09e-01
GO:0043113 receptor clustering	12	4.85e-01	1.17e-01	7.47e-01
GO:0045892 negative regulation of DNA-templated transcription	174	8.29e-03	1.16e-01	8.02e-02
GO:0070847 core mediator complex	19	3.80e-01	-1.16e-01	6.64e-01
GO:0035591 signaling adaptor activity	40	2.05e-01	1.16e-01	4.90e-01
GO:0000776 kinetochore	90	5.76e-02	1.16e-01	2.59e-01
GO:0042149 cellular response to glucose starvation	29	2.81e-01	1.16e-01	5.74e-01
GO:0045494 photoreceptor cell maintenance	25	3.17e-01	-1.16e-01	6.15e-01
GO:0070301 cellular response to hydrogen peroxide	23	3.38e-01	1.16e-01	6.31e-01
GO:0032715 negative regulation of interleukin-6 production	14	4.56e-01	1.15e-01	7.22e-01
GO:0008344 adult locomotory behavior	23	3.40e-01	-1.15e-01	6.33e-01
GO:0005509 calcium ion binding	260	1.47e-03	-1.15e-01	2.41e-02
GO:0007605 sensory perception of sound	55	1.42e-01	-1.15e-01	4.20e-01
GO:0060038 cardiac muscle cell proliferation	12	4.93e-01	1.14e-01	7.54e-01
GO:0003730 mRNA 3’-UTR binding	51	1.58e-01	1.14e-01	4.40e-01
GO:0016358 dendrite development	19	3.88e-01	1.14e-01	6.69e-01
GO:0001508 action potential	11	5.13e-01	1.14e-01	7.73e-01
GO:0009898 cytoplasmic side of plasma membrane	48	1.73e-01	-1.14e-01	4.58e-01
GO:0005769 early endosome	140	2.05e-02	-1.14e-01	1.38e-01
GO:0030971 receptor tyrosine kinase binding	32	2.66e-01	1.14e-01	5.59e-01
GO:0030145 manganese ion binding	45	1.88e-01	-1.13e-01	4.74e-01
GO:0001618 virus receptor activity	10	5.35e-01	1.13e-01	7.87e-01
GO:0021987 cerebral cortex development	25	3.28e-01	1.13e-01	6.24e-01
GO:0098609 cell-cell adhesion	85	7.24e-02	-1.13e-01	2.95e-01
GO:0045214 sarcomere organization	12	4.99e-01	-1.13e-01	7.59e-01
GO:0098656 monoatomic anion transmembrane transport	18	4.09e-01	-1.12e-01	6.91e-01
GO:0035264 multicellular organism growth	67	1.12e-01	1.12e-01	3.75e-01
GO:0006486 protein glycosylation	46	1.89e-01	-1.12e-01	4.74e-01
GO:0016251 RNA polymerase II general transcription initiation factor activity	22	3.64e-01	-1.12e-01	6.53e-01
GO:0033192 calmodulin-dependent protein phosphatase activity	16	4.39e-01	-1.12e-01	7.07e-01
GO:0010634 positive regulation of epithelial cell migration	19	4.01e-01	-1.11e-01	6.82e-01
GO:0007528 neuromuscular junction development	14	4.71e-01	-1.11e-01	7.36e-01
GO:0043495 protein-membrane adaptor activity	17	4.28e-01	-1.11e-01	7.01e-01
GO:0070161 anchoring junction	18	4.15e-01	-1.11e-01	6.93e-01
GO:0008023 transcription elongation factor complex	14	4.73e-01	1.11e-01	7.38e-01
GO:0070534 protein K63-linked ubiquitination	31	2.87e-01	1.11e-01	5.83e-01
GO:0031122 cytoplasmic microtubule organization	28	3.13e-01	1.10e-01	6.10e-01
GO:0005763 mitochondrial small ribosomal subunit	21	3.84e-01	-1.10e-01	6.67e-01
GO:0005876 spindle microtubule	20	3.96e-01	1.10e-01	6.77e-01
GO:0001540 amyloid-beta binding	27	3.25e-01	-1.09e-01	6.22e-01
GO:0001222 transcription corepressor binding	27	3.25e-01	1.09e-01	6.22e-01
GO:0045995 regulation of embryonic development	27	3.27e-01	1.09e-01	6.24e-01
GO:0001750 photoreceptor outer segment	24	3.56e-01	-1.09e-01	6.49e-01
GO:0010628 positive regulation of gene expression	147	2.28e-02	1.09e-01	1.46e-01
GO:0030246 carbohydrate binding	41	2.28e-01	-1.09e-01	5.14e-01
GO:0005524 ATP binding	896	5.07e-08	1.08e-01	4.73e-06
GO:0061077 chaperone-mediated protein folding	16	4.53e-01	-1.08e-01	7.20e-01
GO:0004535 poly(A)-specific ribonuclease activity	10	5.53e-01	-1.08e-01	8.02e-01
GO:0140416 transcription regulator inhibitor activity	12	5.16e-01	1.08e-01	7.76e-01
GO:0097060 synaptic membrane	11	5.34e-01	-1.08e-01	7.87e-01
GO:0030165 PDZ domain binding	29	3.13e-01	-1.08e-01	6.10e-01
GO:0060170 ciliary membrane	19	4.16e-01	-1.08e-01	6.93e-01
GO:0017134 fibroblast growth factor binding	11	5.36e-01	1.08e-01	7.88e-01
GO:0005819 spindle	54	1.71e-01	1.08e-01	4.55e-01
GO:0007517 muscle organ development	12	5.18e-01	-1.08e-01	7.77e-01
GO:0001817 regulation of cytokine production	25	3.52e-01	-1.08e-01	6.46e-01
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway	19	4.17e-01	1.08e-01	6.93e-01
GO:0007266 Rho protein signal transduction	33	2.85e-01	-1.08e-01	5.80e-01
GO:0005543 phospholipid binding	39	2.48e-01	1.07e-01	5.40e-01
GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	35	2.74e-01	-1.07e-01	5.68e-01
GO:0043410 positive regulation of MAPK cascade	61	1.49e-01	-1.07e-01	4.29e-01
GO:0030534 adult behavior	10	5.59e-01	-1.07e-01	8.07e-01
GO:0005912 adherens junction	70	1.23e-01	-1.07e-01	3.94e-01
GO:0016740 transferase activity	23	3.77e-01	1.06e-01	6.61e-01
GO:0005080 protein kinase C binding	17	4.48e-01	1.06e-01	7.14e-01
GO:0048488 synaptic vesicle endocytosis	21	4.00e-01	-1.06e-01	6.82e-01
GO:0046326 positive regulation of D-glucose import	15	4.78e-01	-1.06e-01	7.42e-01
GO:0035102 PRC1 complex	12	5.26e-01	-1.06e-01	7.83e-01
GO:0140297 DNA-binding transcription factor binding	72	1.22e-01	1.06e-01	3.91e-01
GO:0048863 stem cell differentiation	22	3.92e-01	1.05e-01	6.72e-01
GO:0036297 interstrand cross-link repair	24	3.73e-01	1.05e-01	6.59e-01
GO:0051403 stress-activated MAPK cascade	12	5.28e-01	1.05e-01	7.85e-01
GO:0005905 clathrin-coated pit	30	3.21e-01	-1.05e-01	6.18e-01
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding	84	9.75e-02	-1.05e-01	3.47e-01
GO:0032869 cellular response to insulin stimulus	33	2.98e-01	1.05e-01	5.99e-01
GO:0005778 peroxisomal membrane	27	3.47e-01	1.05e-01	6.42e-01
GO:0007613 memory	28	3.39e-01	-1.04e-01	6.33e-01
GO:0046034 ATP metabolic process	12	5.32e-01	1.04e-01	7.87e-01
GO:0140311 protein sequestering activity	18	4.44e-01	1.04e-01	7.11e-01
GO:0016197 endosomal transport	27	3.50e-01	-1.04e-01	6.44e-01
GO:0032743 positive regulation of interleukin-2 production	16	4.72e-01	-1.04e-01	7.37e-01
GO:0051225 spindle assembly	21	4.10e-01	1.04e-01	6.92e-01
GO:0030900 forebrain development	20	4.23e-01	1.04e-01	6.99e-01
GO:0002931 response to ischemia	10	5.71e-01	-1.04e-01	8.10e-01
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process	19	4.35e-01	-1.03e-01	7.05e-01
GO:0030234 enzyme regulator activity	14	5.03e-01	1.03e-01	7.63e-01
GO:0031012 extracellular matrix	91	9.03e-02	-1.03e-01	3.34e-01
GO:0000118 histone deacetylase complex	22	4.04e-01	1.03e-01	6.85e-01
GO:0060324 face development	14	5.07e-01	-1.02e-01	7.66e-01
GO:0031623 receptor internalization	21	4.17e-01	-1.02e-01	6.93e-01
GO:0009897 external side of plasma membrane	106	7.17e-02	-1.01e-01	2.94e-01
GO:0046847 filopodium assembly	11	5.62e-01	-1.01e-01	8.08e-01
GO:0038202 TORC1 signaling	12	5.46e-01	1.01e-01	8.00e-01
GO:0004864 protein phosphatase inhibitor activity	13	5.31e-01	1.00e-01	7.87e-01
GO:0030159 signaling receptor complex adaptor activity	13	5.33e-01	9.98e-02	7.87e-01
GO:0007155 cell adhesion	108	7.48e-02	-9.94e-02	3.00e-01
GO:0008053 mitochondrial fusion	17	4.79e-01	9.91e-02	7.42e-01
GO:0043997 histone H4K12 acetyltransferase activity	10	5.89e-01	9.88e-02	8.25e-01
GO:0007224 smoothened signaling pathway	50	2.28e-01	-9.86e-02	5.14e-01
GO:0070588 calcium ion transmembrane transport	43	2.64e-01	9.86e-02	5.56e-01
GO:0000266 mitochondrial fission	10	5.90e-01	9.84e-02	8.25e-01
GO:0034605 cellular response to heat	16	4.96e-01	9.84e-02	7.57e-01
GO:0007015 actin filament organization	73	1.47e-01	-9.83e-02	4.27e-01
GO:0005768 endosome	113	7.19e-02	-9.81e-02	2.94e-01
GO:0060326 cell chemotaxis	28	3.69e-01	9.81e-02	6.56e-01
GO:0006402 mRNA catabolic process	14	5.26e-01	9.80e-02	7.83e-01
GO:0001837 epithelial to mesenchymal transition	17	4.84e-01	9.80e-02	7.47e-01
GO:0060041 retina development in camera-type eye	21	4.39e-01	-9.77e-02	7.07e-01
GO:0030488 tRNA methylation	20	4.51e-01	9.75e-02	7.17e-01
GO:0043296 apical junction complex	10	5.95e-01	9.71e-02	8.30e-01
GO:0019221 cytokine-mediated signaling pathway	43	2.71e-01	9.71e-02	5.64e-01
GO:0005814 centriole	91	1.12e-01	9.65e-02	3.75e-01
GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site	16	5.05e-01	9.63e-02	7.64e-01
GO:0071539 protein localization to centrosome	20	4.56e-01	9.63e-02	7.22e-01
GO:0009615 response to virus	30	3.62e-01	-9.63e-02	6.53e-01
GO:0071339 MLL1 complex	18	4.80e-01	9.62e-02	7.43e-01
GO:1901223 negative regulation of non-canonical NF-kappaB signal transduction	14	5.34e-01	9.61e-02	7.87e-01
GO:0003148 outflow tract septum morphogenesis	12	5.65e-01	-9.60e-02	8.08e-01
GO:0005198 structural molecule activity	39	3.00e-01	-9.59e-02	6.00e-01
GO:0016525 negative regulation of angiogenesis	36	3.21e-01	9.56e-02	6.19e-01
GO:0043123 positive regulation of canonical NF-kappaB signal transduction	75	1.54e-01	9.53e-02	4.33e-01
GO:0005200 structural constituent of cytoskeleton	28	3.83e-01	-9.53e-02	6.66e-01
GO:0045165 cell fate commitment	20	4.61e-01	9.53e-02	7.26e-01
GO:0005938 cell cortex	74	1.57e-01	-9.52e-02	4.38e-01
GO:0099149 regulation of postsynaptic neurotransmitter receptor internalization	12	5.68e-01	9.51e-02	8.10e-01
GO:0033344 cholesterol efflux	12	5.69e-01	-9.50e-02	8.10e-01
GO:0002020 protease binding	44	2.77e-01	-9.47e-02	5.72e-01
GO:0051301 cell division	144	5.05e-02	9.46e-02	2.40e-01
GO:0050767 regulation of neurogenesis	13	5.55e-01	9.45e-02	8.04e-01
GO:0020037 heme binding	52	2.39e-01	-9.44e-02	5.28e-01
GO:1902358 sulfate transmembrane transport	10	6.07e-01	-9.40e-02	8.38e-01
GO:0005884 actin filament	43	2.88e-01	-9.36e-02	5.85e-01
GO:0090443 FAR/SIN/STRIPAK complex	12	5.76e-01	-9.32e-02	8.13e-01
GO:0002250 adaptive immune response	21	4.60e-01	-9.32e-02	7.25e-01
GO:0007346 regulation of mitotic cell cycle	30	3.80e-01	-9.26e-02	6.64e-01
GO:0032587 ruffle membrane	41	3.05e-01	-9.26e-02	6.03e-01
GO:0002102 podosome	19	4.85e-01	9.25e-02	7.48e-01
GO:0001669 acrosomal vesicle	26	4.15e-01	9.24e-02	6.93e-01
GO:1902895 positive regulation of miRNA transcription	25	4.24e-01	-9.24e-02	6.99e-01
GO:0010592 positive regulation of lamellipodium assembly	10	6.15e-01	9.19e-02	8.43e-01
GO:0004722 protein serine/threonine phosphatase activity	33	3.62e-01	-9.18e-02	6.53e-01
GO:0045746 negative regulation of Notch signaling pathway	14	5.55e-01	9.12e-02	8.03e-01
GO:0032880 regulation of protein localization	42	3.07e-01	-9.12e-02	6.03e-01
GO:0070374 positive regulation of ERK1 and ERK2 cascade	61	2.21e-01	-9.07e-02	5.05e-01
GO:0007099 centriole replication	13	5.72e-01	9.06e-02	8.10e-01
GO:0071526 semaphorin-plexin signaling pathway	25	4.38e-01	8.96e-02	7.07e-01
GO:0045171 intercellular bridge	56	2.47e-01	8.96e-02	5.38e-01
GO:0033209 tumor necrosis factor-mediated signaling pathway	15	5.50e-01	-8.91e-02	8.02e-01
GO:0030054 cell junction	52	2.68e-01	8.89e-02	5.61e-01
GO:0035403 histone H3T6 kinase activity	32	3.85e-01	8.88e-02	6.68e-01
GO:0010824 regulation of centrosome duplication	15	5.52e-01	8.87e-02	8.02e-01
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation	14	5.68e-01	8.81e-02	8.10e-01
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity	19	5.07e-01	8.80e-02	7.66e-01
GO:0061630 ubiquitin protein ligase activity	176	4.60e-02	8.74e-02	2.26e-01
GO:0006511 ubiquitin-dependent protein catabolic process	117	1.04e-01	8.72e-02	3.59e-01
GO:0030544 Hsp70 protein binding	29	4.18e-01	8.70e-02	6.93e-01
GO:0008277 regulation of G protein-coupled receptor signaling pathway	15	5.60e-01	8.69e-02	8.07e-01
GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process	14	5.76e-01	8.64e-02	8.13e-01
GO:0008289 lipid binding	43	3.27e-01	-8.64e-02	6.24e-01
GO:0046982 protein heterodimerization activity	129	9.11e-02	-8.63e-02	3.36e-01
GO:0010977 negative regulation of neuron projection development	18	5.26e-01	8.63e-02	7.83e-01
GO:0001784 phosphotyrosine residue binding	27	4.39e-01	8.60e-02	7.07e-01
GO:0072659 protein localization to plasma membrane	75	1.99e-01	-8.59e-02	4.85e-01
GO:0009267 cellular response to starvation	48	3.06e-01	-8.55e-02	6.03e-01
GO:0016301 kinase activity	14	5.81e-01	-8.51e-02	8.18e-01
GO:0010508 positive regulation of autophagy	39	3.58e-01	-8.51e-02	6.50e-01
GO:0045893 positive regulation of DNA-templated transcription	223	2.89e-02	8.51e-02	1.66e-01
GO:0030036 actin cytoskeleton organization	106	1.31e-01	8.51e-02	4.08e-01
GO:0008154 actin polymerization or depolymerization	12	6.12e-01	-8.47e-02	8.41e-01
GO:0000122 negative regulation of transcription by RNA polymerase II	394	4.12e-03	8.46e-02	5.03e-02
GO:0097009 energy homeostasis	21	5.04e-01	8.43e-02	7.63e-01
GO:0000976 transcription cis-regulatory region binding	55	2.80e-01	8.42e-02	5.74e-01
GO:0042626 ATPase-coupled transmembrane transporter activity	17	5.50e-01	-8.38e-02	8.02e-01
GO:0050660 flavin adenine dinucleotide binding	32	4.12e-01	-8.37e-02	6.93e-01
GO:0008013 beta-catenin binding	46	3.32e-01	-8.27e-02	6.27e-01
GO:0005783 endoplasmic reticulum	431	3.42e-03	-8.26e-02	4.46e-02
GO:0046627 negative regulation of insulin receptor signaling pathway	16	5.69e-01	8.23e-02	8.10e-01
GO:0007596 blood coagulation	26	4.68e-01	-8.23e-02	7.33e-01
GO:0010212 response to ionizing radiation	24	4.86e-01	8.21e-02	7.49e-01
GO:0032868 response to insulin	22	5.06e-01	8.19e-02	7.66e-01
GO:0042391 regulation of membrane potential	13	6.09e-01	-8.19e-02	8.39e-01
GO:2000648 positive regulation of stem cell proliferation	12	6.25e-01	8.15e-02	8.49e-01
GO:0001843 neural tube closure	48	3.30e-01	8.14e-02	6.25e-01
GO:0030175 filopodium	31	4.34e-01	-8.12e-02	7.05e-01
GO:1990023 mitotic spindle midzone	10	6.57e-01	8.11e-02	8.65e-01
GO:0008217 regulation of blood pressure	19	5.41e-01	-8.10e-02	7.94e-01
GO:0007166 cell surface receptor signaling pathway	38	3.88e-01	-8.09e-02	6.69e-01
GO:0031624 ubiquitin conjugating enzyme binding	17	5.64e-01	-8.07e-02	8.08e-01
GO:0000145 exocyst	11	6.44e-01	-8.06e-02	8.58e-01
GO:0030100 regulation of endocytosis	12	6.30e-01	-8.04e-02	8.51e-01
GO:0030946 protein tyrosine phosphatase activity, metal-dependent	15	5.90e-01	8.03e-02	8.25e-01
GO:0140793 histone H2AXY142 phosphatase activity	15	5.90e-01	8.03e-02	8.25e-01
GO:0051604 protein maturation	20	5.34e-01	-8.03e-02	7.87e-01
GO:2000042 negative regulation of double-strand break repair via homologous recombination	16	5.78e-01	8.03e-02	8.15e-01
GO:0031124 mRNA 3’-end processing	13	6.17e-01	8.02e-02	8.44e-01
GO:0016323 basolateral plasma membrane	96	1.76e-01	-8.01e-02	4.60e-01
GO:0030215 semaphorin receptor binding	13	6.17e-01	-8.00e-02	8.45e-01
GO:0035725 sodium ion transmembrane transport	45	3.56e-01	-7.96e-02	6.49e-01
GO:0007264 small GTPase-mediated signal transduction	47	3.46e-01	-7.96e-02	6.40e-01
GO:0012505 endomembrane system	97	1.76e-01	-7.96e-02	4.60e-01
GO:0045177 apical part of cell	35	4.17e-01	-7.94e-02	6.93e-01
GO:0007218 neuropeptide signaling pathway	14	6.07e-01	7.93e-02	8.38e-01
GO:0009792 embryo development ending in birth or egg hatching	10	6.65e-01	7.92e-02	8.67e-01
GO:0003007 heart morphogenesis	16	5.84e-01	-7.91e-02	8.21e-01
GO:0000922 spindle pole	69	2.57e-01	7.90e-02	5.50e-01
GO:0005811 lipid droplet	43	3.70e-01	-7.90e-02	6.58e-01
GO:0016529 sarcoplasmic reticulum	14	6.09e-01	-7.90e-02	8.39e-01
GO:0006631 fatty acid metabolic process	34	4.26e-01	-7.89e-02	7.00e-01
GO:0010718 positive regulation of epithelial to mesenchymal transition	26	4.88e-01	-7.87e-02	7.49e-01
GO:0030332 cyclin binding	20	5.43e-01	-7.86e-02	7.96e-01
GO:0007165 signal transduction	267	2.77e-02	-7.85e-02	1.62e-01
GO:0061484 hematopoietic stem cell homeostasis	12	6.38e-01	-7.84e-02	8.54e-01
GO:0060412 ventricular septum morphogenesis	17	5.77e-01	-7.81e-02	8.14e-01
GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity	13	6.26e-01	-7.81e-02	8.49e-01
GO:0070628 proteasome binding	13	6.27e-01	7.79e-02	8.49e-01
GO:1904019 epithelial cell apoptotic process	13	6.27e-01	-7.78e-02	8.49e-01
GO:0006355 regulation of DNA-templated transcription	160	9.03e-02	7.77e-02	3.34e-01
GO:0007628 adult walking behavior	11	6.56e-01	-7.76e-02	8.64e-01
GO:0002088 lens development in camera-type eye	13	6.30e-01	-7.72e-02	8.51e-01
GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction	36	4.23e-01	-7.72e-02	6.99e-01
GO:0032991 protein-containing complex	204	5.82e-02	7.71e-02	2.60e-01
GO:0051020 GTPase binding	15	6.05e-01	-7.70e-02	8.38e-01
GO:0008593 regulation of Notch signaling pathway	10	6.74e-01	-7.69e-02	8.71e-01
GO:0030163 protein catabolic process	31	4.59e-01	7.68e-02	7.25e-01
GO:0042734 presynaptic membrane	37	4.22e-01	7.64e-02	6.98e-01
GO:0060291 long-term synaptic potentiation	11	6.63e-01	7.60e-02	8.66e-01
GO:0007017 microtubule-based process	11	6.63e-01	-7.59e-02	8.66e-01
GO:0030490 maturation of SSU-rRNA	12	6.49e-01	7.59e-02	8.60e-01
GO:0043029 T cell homeostasis	13	6.37e-01	7.56e-02	8.54e-01
GO:0006417 regulation of translation	44	3.89e-01	7.51e-02	6.69e-01
GO:0030206 chondroitin sulfate biosynthetic process	11	6.67e-01	-7.50e-02	8.67e-01
GO:0051233 spindle midzone	17	5.94e-01	7.46e-02	8.29e-01
GO:0006897 endocytosis	92	2.17e-01	-7.45e-02	4.99e-01
GO:0035615 clathrin adaptor activity	10	6.83e-01	-7.45e-02	8.76e-01
GO:0035082 axoneme assembly	10	6.84e-01	7.45e-02	8.76e-01
GO:0032465 regulation of cytokinesis	23	5.37e-01	7.44e-02	7.89e-01
GO:0030134 COPII-coated ER to Golgi transport vesicle	21	5.56e-01	-7.43e-02	8.04e-01
GO:0043204 perikaryon	36	4.41e-01	-7.42e-02	7.09e-01
GO:0030335 positive regulation of cell migration	109	1.82e-01	-7.41e-02	4.66e-01
GO:1900181 negative regulation of protein localization to nucleus	11	6.70e-01	7.41e-02	8.70e-01
GO:0030141 secretory granule	18	5.88e-01	-7.37e-02	8.25e-01
GO:0044297 cell body	24	5.32e-01	7.37e-02	7.87e-01
GO:0050679 positive regulation of epithelial cell proliferation	20	5.69e-01	7.35e-02	8.10e-01
GO:0005637 nuclear inner membrane	24	5.34e-01	7.33e-02	7.87e-01
GO:0045747 positive regulation of Notch signaling pathway	22	5.52e-01	-7.33e-02	8.02e-01
GO:0042327 positive regulation of phosphorylation	12	6.61e-01	-7.31e-02	8.66e-01
GO:0035116 embryonic hindlimb morphogenesis	12	6.62e-01	7.30e-02	8.66e-01
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding	13	6.49e-01	-7.30e-02	8.60e-01
GO:0019904 protein domain specific binding	105	1.98e-01	-7.28e-02	4.85e-01
GO:0001974 blood vessel remodeling	15	6.26e-01	-7.27e-02	8.49e-01
GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction	21	5.64e-01	-7.27e-02	8.08e-01
GO:0016042 lipid catabolic process	29	4.98e-01	7.27e-02	7.59e-01
GO:0019900 kinase binding	49	3.80e-01	-7.26e-02	6.63e-01
GO:0005813 centrosome	344	2.18e-02	7.23e-02	1.42e-01
GO:0048675 axon extension	16	6.18e-01	7.19e-02	8.46e-01
GO:0048487 beta-tubulin binding	22	5.60e-01	-7.18e-02	8.07e-01
GO:0006952 defense response	10	6.94e-01	7.18e-02	8.85e-01
GO:0007405 neuroblast proliferation	21	5.71e-01	-7.14e-02	8.10e-01
GO:0006633 fatty acid biosynthetic process	22	5.64e-01	-7.11e-02	8.08e-01
GO:0032729 positive regulation of type II interferon production	22	5.64e-01	7.11e-02	8.08e-01
GO:0071889 14-3-3 protein binding	15	6.34e-01	7.10e-02	8.53e-01
GO:0016328 lateral plasma membrane	24	5.48e-01	-7.09e-02	8.02e-01
GO:0007507 heart development	80	2.74e-01	-7.08e-02	5.68e-01
GO:0008198 ferrous iron binding	12	6.72e-01	-7.06e-02	8.71e-01
GO:0035904 aorta development	15	6.36e-01	7.05e-02	8.54e-01
GO:0016324 apical plasma membrane	121	1.82e-01	-7.03e-02	4.66e-01
GO:0010507 negative regulation of autophagy	22	5.69e-01	-7.01e-02	8.10e-01
GO:0044458 motile cilium assembly	12	6.74e-01	-7.01e-02	8.71e-01
GO:0043536 positive regulation of blood vessel endothelial cell migration	18	6.08e-01	6.99e-02	8.38e-01
GO:0043001 Golgi to plasma membrane protein transport	21	5.79e-01	6.99e-02	8.16e-01
GO:0005085 guanyl-nucleotide exchange factor activity	144	1.49e-01	-6.97e-02	4.29e-01
GO:0003756 protein disulfide isomerase activity	10	7.03e-01	-6.96e-02	8.89e-01
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding	391	1.89e-02	6.95e-02	1.31e-01
GO:0005776 autophagosome	41	4.44e-01	-6.92e-02	7.11e-01
GO:1990138 neuron projection extension	10	7.06e-01	6.89e-02	8.90e-01
GO:0005834 heterotrimeric G-protein complex	19	6.04e-01	-6.88e-02	8.37e-01
GO:0007288 sperm axoneme assembly	17	6.27e-01	6.82e-02	8.49e-01
GO:0055013 cardiac muscle cell development	11	6.97e-01	-6.78e-02	8.87e-01
GO:0031267 small GTPase binding	167	1.32e-01	6.77e-02	4.09e-01
GO:0031167 rRNA methylation	11	6.98e-01	6.76e-02	8.87e-01
GO:0004674 protein serine/threonine kinase activity	203	9.84e-02	6.74e-02	3.47e-01
GO:0032956 regulation of actin cytoskeleton organization	38	4.72e-01	-6.74e-02	7.37e-01
GO:0050808 synapse organization	17	6.31e-01	6.73e-02	8.51e-01
GO:0005019 platelet-derived growth factor beta-receptor activity	15	6.52e-01	-6.73e-02	8.62e-01
GO:0009410 response to xenobiotic stimulus	47	4.26e-01	6.71e-02	7.00e-01
GO:0031418 L-ascorbic acid binding	14	6.65e-01	-6.68e-02	8.67e-01
GO:0030170 pyridoxal phosphate binding	33	5.08e-01	-6.67e-02	7.66e-01
GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	78	3.09e-01	-6.67e-02	6.05e-01
GO:0007369 gastrulation	10	7.16e-01	6.66e-02	8.96e-01
GO:0045599 negative regulation of fat cell differentiation	21	5.99e-01	-6.63e-02	8.33e-01
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation	30	5.30e-01	6.63e-02	7.86e-01
GO:0015026 coreceptor activity	13	6.80e-01	6.61e-02	8.75e-01
GO:0045879 negative regulation of smoothened signaling pathway	16	6.47e-01	6.61e-02	8.60e-01
GO:0005689 U12-type spliceosomal complex	20	6.09e-01	6.61e-02	8.39e-01
GO:0044322 endoplasmic reticulum quality control compartment	11	7.04e-01	6.61e-02	8.89e-01
GO:0010595 positive regulation of endothelial cell migration	27	5.53e-01	-6.61e-02	8.02e-01
GO:0032526 response to retinoic acid	15	6.59e-01	6.58e-02	8.66e-01
GO:0004519 endonuclease activity	13	6.82e-01	6.57e-02	8.75e-01
GO:0048536 spleen development	23	5.86e-01	-6.57e-02	8.22e-01
GO:0007286 spermatid development	25	5.70e-01	6.56e-02	8.10e-01
GO:0005634 nucleus	2130	1.45e-06	6.53e-02	9.55e-05
GO:0015459 potassium channel regulator activity	16	6.51e-01	-6.53e-02	8.62e-01
GO:0030133 transport vesicle	22	5.97e-01	-6.52e-02	8.31e-01
GO:0048012 hepatocyte growth factor receptor signaling pathway	19	6.23e-01	6.51e-02	8.49e-01
GO:0001764 neuron migration	40	4.77e-01	6.51e-02	7.41e-01
GO:0043122 regulation of canonical NF-kappaB signal transduction	18	6.33e-01	6.50e-02	8.53e-01
GO:0005801 cis-Golgi network	28	5.52e-01	-6.49e-02	8.02e-01
GO:1901673 regulation of mitotic spindle assembly	16	6.54e-01	-6.48e-02	8.63e-01
GO:0035869 ciliary transition zone	22	6.00e-01	6.46e-02	8.34e-01
GO:0005791 rough endoplasmic reticulum	12	6.99e-01	6.45e-02	8.87e-01
GO:0036503 ERAD pathway	59	3.93e-01	6.44e-02	6.72e-01
GO:0033290 eukaryotic 48S preinitiation complex	13	6.90e-01	6.39e-02	8.82e-01
GO:0001894 tissue homeostasis	13	6.90e-01	-6.39e-02	8.82e-01
GO:0019706 protein-cysteine S-palmitoyltransferase activity	17	6.48e-01	6.39e-02	8.60e-01
GO:0035331 negative regulation of hippo signaling	18	6.39e-01	6.39e-02	8.54e-01
GO:0030182 neuron differentiation	55	4.15e-01	6.36e-02	6.93e-01
GO:0042470 melanosome	28	5.61e-01	-6.35e-02	8.08e-01
GO:0036342 post-anal tail morphogenesis	11	7.16e-01	6.35e-02	8.96e-01
GO:0035401 histone H3Y41 kinase activity	23	5.99e-01	6.34e-02	8.33e-01
GO:0005925 focal adhesion	114	2.44e-01	-6.33e-02	5.35e-01
GO:0036211 protein modification process	16	6.62e-01	-6.32e-02	8.66e-01
GO:0071949 FAD binding	27	5.70e-01	-6.31e-02	8.10e-01
GO:0045944 positive regulation of transcription by RNA polymerase II	526	1.41e-02	6.29e-02	1.07e-01
GO:0006284 base-excision repair	17	6.54e-01	6.28e-02	8.63e-01
GO:0040018 positive regulation of multicellular organism growth	16	6.64e-01	6.28e-02	8.66e-01
GO:0045880 positive regulation of smoothened signaling pathway	23	6.03e-01	-6.27e-02	8.37e-01
GO:0003700 DNA-binding transcription factor activity	79	3.37e-01	6.26e-02	6.30e-01
GO:0097150 neuronal stem cell population maintenance	18	6.49e-01	-6.20e-02	8.60e-01
GO:0042147 retrograde transport, endosome to Golgi	50	4.49e-01	-6.19e-02	7.15e-01
GO:0050770 regulation of axonogenesis	13	6.99e-01	6.19e-02	8.87e-01
GO:0030424 axon	122	2.40e-01	-6.17e-02	5.29e-01
GO:0000287 magnesium ion binding	150	1.95e-01	-6.14e-02	4.81e-01
GO:0098552 side of membrane	17	6.62e-01	-6.12e-02	8.66e-01
GO:0009636 response to toxic substance	15	6.82e-01	-6.11e-02	8.75e-01
GO:0003341 cilium movement	10	7.38e-01	-6.11e-02	9.09e-01
GO:1990247 N6-methyladenosine-containing RNA reader activity	10	7.38e-01	6.10e-02	9.09e-01
GO:0005739 mitochondrion	607	1.12e-02	-6.07e-02	9.28e-02
GO:0043130 ubiquitin binding	61	4.13e-01	6.07e-02	6.93e-01
GO:0003333 amino acid transmembrane transport	10	7.40e-01	6.06e-02	9.10e-01
GO:0016282 eukaryotic 43S preinitiation complex	14	6.95e-01	6.06e-02	8.85e-01
GO:0050885 neuromuscular process controlling balance	24	6.07e-01	-6.06e-02	8.38e-01
GO:0004888 transmembrane signaling receptor activity	23	6.15e-01	6.06e-02	8.43e-01
GO:0019843 rRNA binding	22	6.23e-01	-6.05e-02	8.49e-01
GO:0032760 positive regulation of tumor necrosis factor production	33	5.48e-01	-6.04e-02	8.02e-01
GO:0006915 apoptotic process	135	2.27e-01	-6.04e-02	5.13e-01
GO:0010467 gene expression	81	3.50e-01	-6.01e-02	6.44e-01
GO:0070062 extracellular exosome	38	5.22e-01	-6.00e-02	7.81e-01
GO:0051117 ATPase binding	44	4.92e-01	5.99e-02	7.53e-01
GO:0043524 negative regulation of neuron apoptotic process	52	4.56e-01	5.98e-02	7.22e-01
GO:0071363 cellular response to growth factor stimulus	20	6.45e-01	-5.96e-02	8.58e-01
GO:0030295 protein kinase activator activity	21	6.38e-01	-5.93e-02	8.54e-01
GO:0090090 negative regulation of canonical Wnt signaling pathway	71	3.88e-01	-5.92e-02	6.69e-01
GO:0009986 cell surface	179	1.74e-01	-5.91e-02	4.58e-01
GO:0000165 MAPK cascade	46	4.89e-01	5.89e-02	7.51e-01
GO:0000049 tRNA binding	52	4.63e-01	5.89e-02	7.27e-01
GO:0005741 mitochondrial outer membrane	94	3.25e-01	-5.88e-02	6.22e-01
GO:0043240 Fanconi anaemia nuclear complex	11	7.36e-01	-5.88e-02	9.09e-01
GO:0140326 ATPase-coupled intramembrane lipid transporter activity	11	7.37e-01	-5.85e-02	9.09e-01
GO:1990573 potassium ion import across plasma membrane	17	6.77e-01	5.83e-02	8.74e-01
GO:0007219 Notch signaling pathway	41	5.20e-01	-5.81e-02	7.79e-01
GO:0005669 transcription factor TFIID complex	22	6.38e-01	-5.79e-02	8.54e-01
GO:0007030 Golgi organization	63	4.28e-01	-5.78e-02	7.01e-01
GO:0070888 E-box binding	21	6.47e-01	5.78e-02	8.60e-01
GO:0001818 negative regulation of cytokine production	11	7.41e-01	-5.76e-02	9.10e-01
GO:0005158 insulin receptor binding	13	7.20e-01	5.75e-02	8.99e-01
GO:0071944 cell periphery	12	7.31e-01	-5.74e-02	9.08e-01
GO:0007275 multicellular organism development	27	6.06e-01	5.74e-02	8.38e-01
GO:0005795 Golgi stack	18	6.74e-01	5.72e-02	8.71e-01
GO:0140801 histone H2AXY142 kinase activity	24	6.28e-01	5.71e-02	8.50e-01
GO:0030031 cell projection assembly	10	7.54e-01	-5.71e-02	9.15e-01
GO:0050804 modulation of chemical synaptic transmission	35	5.60e-01	-5.69e-02	8.07e-01
GO:0009925 basal plasma membrane	12	7.36e-01	-5.62e-02	9.09e-01
GO:0031648 protein destabilization	32	5.85e-01	-5.58e-02	8.21e-01
GO:0007519 skeletal muscle tissue development	17	6.91e-01	-5.58e-02	8.82e-01
GO:0004721 phosphoprotein phosphatase activity	21	6.61e-01	-5.52e-02	8.66e-01
GO:0051259 protein complex oligomerization	14	7.21e-01	5.51e-02	9.00e-01
GO:0006623 protein targeting to vacuole	11	7.52e-01	5.50e-02	9.14e-01
GO:0090128 regulation of synapse maturation	10	7.64e-01	5.48e-02	9.22e-01
GO:0000139 Golgi membrane	263	1.28e-01	-5.48e-02	4.02e-01
GO:0045766 positive regulation of angiogenesis	53	4.91e-01	-5.47e-02	7.53e-01
GO:0071364 cellular response to epidermal growth factor stimulus	19	6.81e-01	5.45e-02	8.75e-01
GO:0004521 RNA endonuclease activity	20	6.74e-01	-5.44e-02	8.71e-01
GO:0038109 Kit signaling pathway	16	7.07e-01	-5.43e-02	8.90e-01
GO:0050750 low-density lipoprotein particle receptor binding	13	7.35e-01	5.43e-02	9.09e-01
GO:0007173 epidermal growth factor receptor signaling pathway	40	5.53e-01	5.43e-02	8.02e-01
GO:0032496 response to lipopolysaccharide	37	5.68e-01	-5.43e-02	8.10e-01
GO:0030514 negative regulation of BMP signaling pathway	27	6.26e-01	-5.42e-02	8.49e-01
GO:0032580 Golgi cisterna membrane	26	6.34e-01	-5.40e-02	8.53e-01
GO:0010008 endosome membrane	86	3.89e-01	-5.38e-02	6.69e-01
GO:0046872 metal ion binding	874	7.65e-03	5.37e-02	7.79e-02
GO:0044325 transmembrane transporter binding	58	4.80e-01	5.36e-02	7.43e-01
GO:0034142 toll-like receptor 4 signaling pathway	14	7.31e-01	5.31e-02	9.08e-01
GO:0046718 symbiont entry into host cell	22	6.67e-01	5.30e-02	8.67e-01
GO:0007029 endoplasmic reticulum organization	16	7.15e-01	5.27e-02	8.96e-01
GO:0005006 epidermal growth factor receptor activity	16	7.16e-01	-5.26e-02	8.96e-01
GO:0070382 exocytic vesicle	10	7.73e-01	-5.26e-02	9.25e-01
GO:0043005 neuron projection	97	3.71e-01	-5.26e-02	6.58e-01
GO:0045669 positive regulation of osteoblast differentiation	37	5.80e-01	5.26e-02	8.17e-01
GO:0030018 Z disc	51	5.18e-01	5.24e-02	7.77e-01
GO:0004714 transmembrane receptor protein tyrosine kinase activity	15	7.27e-01	5.21e-02	9.04e-01
GO:1901379 regulation of potassium ion transmembrane transport	10	7.75e-01	-5.21e-02	9.26e-01
GO:0042177 negative regulation of protein catabolic process	24	6.60e-01	-5.20e-02	8.66e-01
GO:0038023 signaling receptor activity	40	5.72e-01	-5.16e-02	8.10e-01
GO:0070098 chemokine-mediated signaling pathway	10	7.77e-01	-5.16e-02	9.26e-01
GO:0051649 establishment of localization in cell	41	5.68e-01	-5.15e-02	8.10e-01
GO:0008104 protein localization	68	4.63e-01	-5.15e-02	7.27e-01
GO:0030864 cortical actin cytoskeleton	31	6.20e-01	-5.15e-02	8.47e-01
GO:0120162 positive regulation of cold-induced thermogenesis	29	6.33e-01	5.13e-02	8.53e-01
GO:0004622 lysophospholipase activity	10	7.79e-01	5.12e-02	9.26e-01
GO:0070273 phosphatidylinositol-4-phosphate binding	17	7.15e-01	5.11e-02	8.96e-01
GO:0032543 mitochondrial translation	22	6.80e-01	-5.08e-02	8.75e-01
GO:0008168 methyltransferase activity	13	7.52e-01	5.06e-02	9.14e-01
GO:0004672 protein kinase activity	64	4.87e-01	5.02e-02	7.49e-01
GO:0005254 chloride channel activity	19	7.05e-01	5.02e-02	8.89e-01
GO:0043542 endothelial cell migration	14	7.46e-01	-5.00e-02	9.10e-01
GO:0006612 protein targeting to membrane	24	6.73e-01	4.97e-02	8.71e-01
GO:0005005 transmembrane-ephrin receptor activity	16	7.33e-01	4.92e-02	9.09e-01
GO:0042803 protein homodimerization activity	369	1.06e-01	-4.92e-02	3.64e-01
GO:0030136 clathrin-coated vesicle	29	6.47e-01	-4.91e-02	8.60e-01
GO:0043687 post-translational protein modification	19	7.11e-01	4.91e-02	8.94e-01
GO:0006357 regulation of transcription by RNA polymerase II	546	5.17e-02	4.90e-02	2.45e-01
GO:0005794 Golgi apparatus	466	7.18e-02	-4.90e-02	2.94e-01
GO:0016020 membrane	955	1.13e-02	-4.90e-02	9.28e-02
GO:0030220 platelet formation	11	7.79e-01	4.88e-02	9.26e-01
GO:0030374 nuclear receptor coactivator activity	30	6.44e-01	4.87e-02	8.58e-01
GO:0010506 regulation of autophagy	26	6.68e-01	-4.86e-02	8.68e-01
GO:0060079 excitatory postsynaptic potential	16	7.38e-01	-4.84e-02	9.09e-01
GO:0010976 positive regulation of neuron projection development	32	6.36e-01	4.83e-02	8.54e-01
GO:0045087 innate immune response	80	4.55e-01	4.83e-02	7.22e-01
GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	12	7.73e-01	4.82e-02	9.25e-01
GO:0006629 lipid metabolic process	52	5.49e-01	-4.80e-02	8.02e-01
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway	12	7.73e-01	4.80e-02	9.25e-01
GO:0007186 G protein-coupled receptor signaling pathway	90	4.32e-01	4.80e-02	7.03e-01
GO:0005515 protein binding	91	4.30e-01	4.80e-02	7.01e-01
GO:0072657 protein localization to membrane	19	7.18e-01	4.79e-02	8.98e-01
GO:0060395 SMAD protein signal transduction	14	7.59e-01	-4.73e-02	9.18e-01
GO:0034394 protein localization to cell surface	17	7.36e-01	-4.72e-02	9.09e-01
GO:0045814 negative regulation of gene expression, epigenetic	16	7.44e-01	4.72e-02	9.10e-01
GO:0008285 negative regulation of cell population proliferation	117	3.79e-01	-4.72e-02	6.62e-01
GO:0000209 protein polyubiquitination	77	4.77e-01	-4.69e-02	7.41e-01
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle	26	6.79e-01	4.69e-02	8.75e-01
GO:0005506 iron ion binding	64	5.17e-01	4.69e-02	7.77e-01
GO:0036464 cytoplasmic ribonucleoprotein granule	36	6.27e-01	-4.68e-02	8.49e-01
GO:0035115 embryonic forelimb morphogenesis	16	7.47e-01	-4.66e-02	9.10e-01
GO:0007626 locomotory behavior	28	6.70e-01	-4.65e-02	8.70e-01
GO:0006816 calcium ion transport	19	7.26e-01	-4.65e-02	9.04e-01
GO:0005125 cytokine activity	27	6.77e-01	4.64e-02	8.73e-01
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific	346	1.40e-01	4.63e-02	4.17e-01
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway	40	6.14e-01	-4.61e-02	8.43e-01
GO:0016477 cell migration	137	3.55e-01	-4.59e-02	6.49e-01
GO:0035091 phosphatidylinositol binding	74	4.96e-01	-4.58e-02	7.57e-01
GO:0070507 regulation of microtubule cytoskeleton organization	15	7.59e-01	4.58e-02	9.18e-01
GO:0004252 serine-type endopeptidase activity	51	5.73e-01	-4.57e-02	8.10e-01
GO:0015701 bicarbonate transport	12	7.85e-01	-4.55e-02	9.26e-01
GO:0090314 positive regulation of protein targeting to membrane	12	7.86e-01	-4.53e-02	9.26e-01
GO:0030073 insulin secretion	13	7.78e-01	4.52e-02	9.26e-01
GO:0008033 tRNA processing	15	7.66e-01	-4.44e-02	9.22e-01
GO:0048741 skeletal muscle fiber development	16	7.58e-01	-4.44e-02	9.18e-01
GO:0004713 protein tyrosine kinase activity	34	6.58e-01	4.39e-02	8.66e-01
GO:0090263 positive regulation of canonical Wnt signaling pathway	62	5.51e-01	4.38e-02	8.02e-01
GO:0050839 cell adhesion molecule binding	20	7.35e-01	4.38e-02	9.09e-01
GO:0070936 protein K48-linked ubiquitination	68	5.33e-01	4.37e-02	7.87e-01
GO:0005770 late endosome	75	5.18e-01	-4.32e-02	7.77e-01
GO:0043616 keratinocyte proliferation	11	8.04e-01	-4.32e-02	9.37e-01
GO:0006508 proteolysis	175	3.29e-01	-4.29e-02	6.24e-01
GO:0050852 T cell receptor signaling pathway	49	6.04e-01	4.29e-02	8.37e-01
GO:0030522 intracellular receptor signaling pathway	18	7.53e-01	-4.29e-02	9.14e-01
GO:1990837 sequence-specific double-stranded DNA binding	47	6.12e-01	-4.27e-02	8.42e-01
GO:0043066 negative regulation of apoptotic process	150	3.68e-01	-4.27e-02	6.55e-01
GO:0070371 ERK1 and ERK2 cascade	19	7.49e-01	-4.25e-02	9.12e-01
GO:0036064 ciliary basal body	103	4.59e-01	4.23e-02	7.24e-01
GO:0014032 neural crest cell development	11	8.09e-01	-4.20e-02	9.39e-01
GO:0051592 response to calcium ion	20	7.46e-01	-4.19e-02	9.10e-01
GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels	16	7.73e-01	-4.18e-02	9.25e-01
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific	180	3.35e-01	4.17e-02	6.29e-01
GO:0007399 nervous system development	88	5.02e-01	-4.15e-02	7.62e-01
GO:0046330 positive regulation of JNK cascade	38	6.59e-01	-4.14e-02	8.66e-01
GO:0007281 germ cell development	14	7.89e-01	-4.13e-02	9.29e-01
GO:0030154 cell differentiation	141	3.99e-01	-4.12e-02	6.81e-01
GO:0006954 inflammatory response	81	5.24e-01	-4.10e-02	7.81e-01
GO:0060218 hematopoietic stem cell differentiation	11	8.14e-01	4.09e-02	9.40e-01
GO:0045773 positive regulation of axon extension	10	8.23e-01	4.09e-02	9.42e-01
GO:0051018 protein kinase A binding	12	8.07e-01	4.08e-02	9.38e-01
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding	83	5.23e-01	4.06e-02	7.81e-01
GO:0005829 cytosol	2017	3.53e-03	4.04e-02	4.53e-02
GO:0019903 protein phosphatase binding	50	6.21e-01	4.04e-02	8.48e-01
GO:0014704 intercalated disc	14	7.94e-01	-4.03e-02	9.31e-01
GO:0001756 somitogenesis	25	7.31e-01	3.98e-02	9.08e-01
GO:0046854 phosphatidylinositol phosphate biosynthetic process	18	7.71e-01	3.97e-02	9.25e-01
GO:0000151 ubiquitin ligase complex	48	6.34e-01	3.97e-02	8.53e-01
GO:0098978 glutamatergic synapse	234	2.97e-01	-3.97e-02	5.97e-01
GO:0008266 poly(U) RNA binding	16	7.84e-01	3.95e-02	9.26e-01
GO:0015629 actin cytoskeleton	114	4.68e-01	-3.94e-02	7.33e-01
GO:0006513 protein monoubiquitination	27	7.23e-01	3.94e-02	9.01e-01
GO:0001732 formation of cytoplasmic translation initiation complex	12	8.13e-01	3.94e-02	9.40e-01
GO:0098839 postsynaptic density membrane	34	6.92e-01	3.93e-02	8.83e-01
GO:0060976 coronary vasculature development	18	7.73e-01	3.93e-02	9.25e-01
GO:0034244 negative regulation of transcription elongation by RNA polymerase II	13	8.06e-01	-3.93e-02	9.38e-01
GO:0008270 zinc ion binding	398	1.82e-01	3.92e-02	4.66e-01
GO:0030334 regulation of cell migration	35	6.89e-01	-3.91e-02	8.82e-01
GO:0090141 positive regulation of mitochondrial fission	16	7.87e-01	-3.91e-02	9.27e-01
GO:0008076 voltage-gated potassium channel complex	23	7.46e-01	3.90e-02	9.10e-01
GO:0046849 bone remodeling	10	8.33e-01	-3.86e-02	9.43e-01
GO:0000993 RNA polymerase II complex binding	23	7.50e-01	-3.84e-02	9.12e-01
GO:0047496 vesicle transport along microtubule	11	8.26e-01	3.83e-02	9.43e-01
GO:0045732 positive regulation of protein catabolic process	47	6.54e-01	-3.78e-02	8.63e-01
GO:0005112 Notch binding	12	8.21e-01	3.77e-02	9.42e-01
GO:0008083 growth factor activity	40	6.81e-01	3.76e-02	8.75e-01
GO:0007214 gamma-aminobutyric acid signaling pathway	11	8.29e-01	-3.76e-02	9.43e-01
GO:0035924 cellular response to vascular endothelial growth factor stimulus	15	8.02e-01	-3.75e-02	9.35e-01
GO:0051787 misfolded protein binding	12	8.22e-01	3.75e-02	9.42e-01
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway	28	7.32e-01	-3.74e-02	9.08e-01
GO:0071011 precatalytic spliceosome	12	8.23e-01	3.74e-02	9.42e-01
GO:0004198 calcium-dependent cysteine-type endopeptidase activity	10	8.38e-01	3.72e-02	9.43e-01
GO:0007254 JNK cascade	26	7.43e-01	3.72e-02	9.10e-01
GO:1904263 positive regulation of TORC1 signaling	35	7.04e-01	-3.71e-02	8.89e-01
GO:0006622 protein targeting to lysosome	15	8.04e-01	-3.70e-02	9.37e-01
GO:0071356 cellular response to tumor necrosis factor	37	6.98e-01	-3.69e-02	8.87e-01
GO:0045931 positive regulation of mitotic cell cycle	14	8.12e-01	-3.67e-02	9.40e-01
GO:0071805 potassium ion transmembrane transport	38	6.97e-01	-3.65e-02	8.87e-01
GO:0000502 proteasome complex	13	8.20e-01	3.65e-02	9.42e-01
GO:0048147 negative regulation of fibroblast proliferation	15	8.07e-01	3.64e-02	9.38e-01
GO:0035791 platelet-derived growth factor receptor-beta signaling pathway	17	7.96e-01	-3.63e-02	9.31e-01
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway	11	8.35e-01	3.63e-02	9.43e-01
GO:0065003 protein-containing complex assembly	37	7.03e-01	-3.62e-02	8.89e-01
GO:0048384 retinoic acid receptor signaling pathway	11	8.36e-01	3.60e-02	9.43e-01
GO:1990904 ribonucleoprotein complex	104	5.28e-01	3.59e-02	7.85e-01
GO:0008408 3’-5’ exonuclease activity	10	8.45e-01	3.58e-02	9.43e-01
GO:0005008 hepatocyte growth factor receptor activity	15	8.10e-01	3.58e-02	9.40e-01
GO:1904294 positive regulation of ERAD pathway	10	8.45e-01	-3.57e-02	9.43e-01
GO:0032467 positive regulation of cytokinesis	14	8.17e-01	3.57e-02	9.41e-01
GO:0016592 mediator complex	28	7.44e-01	3.57e-02	9.10e-01
GO:0007032 endosome organization	28	7.46e-01	3.54e-02	9.10e-01
GO:0003924 GTPase activity	176	4.24e-01	-3.50e-02	6.99e-01
GO:0030890 positive regulation of B cell proliferation	21	7.82e-01	3.49e-02	9.26e-01
GO:0009982 pseudouridine synthase activity	12	8.35e-01	3.47e-02	9.43e-01
GO:0005886 plasma membrane	1528	2.64e-02	-3.47e-02	1.58e-01
GO:0000086 G2/M transition of mitotic cell cycle	25	7.66e-01	3.44e-02	9.22e-01
GO:0072583 clathrin-dependent endocytosis	19	7.95e-01	-3.44e-02	9.31e-01
GO:0070527 platelet aggregation	16	8.15e-01	-3.38e-02	9.40e-01
GO:0019905 syntaxin binding	25	7.72e-01	3.35e-02	9.25e-01
GO:0042733 embryonic digit morphogenesis	30	7.53e-01	-3.33e-02	9.14e-01
GO:0005789 endoplasmic reticulum membrane	404	2.55e-01	-3.31e-02	5.48e-01
GO:0071816 tail-anchored membrane protein insertion into ER membrane	10	8.56e-01	-3.31e-02	9.44e-01
GO:0042073 intraciliary transport	16	8.19e-01	3.30e-02	9.42e-01
GO:0030866 cortical actin cytoskeleton organization	20	8.01e-01	3.25e-02	9.35e-01
GO:0042632 cholesterol homeostasis	40	7.22e-01	-3.25e-02	9.01e-01
GO:0043197 dendritic spine	46	7.04e-01	-3.24e-02	8.89e-01
GO:0016567 protein ubiquitination	155	4.89e-01	3.23e-02	7.51e-01
GO:0061024 membrane organization	13	8.41e-01	-3.22e-02	9.43e-01
GO:0009952 anterior/posterior pattern specification	42	7.18e-01	-3.22e-02	8.98e-01
GO:0042060 wound healing	29	7.67e-01	-3.17e-02	9.24e-01
GO:0046580 negative regulation of Ras protein signal transduction	13	8.43e-01	-3.17e-02	9.43e-01
GO:0000166 nucleotide binding	37	7.41e-01	3.15e-02	9.10e-01
GO:0043231 intracellular membrane-bounded organelle	118	5.56e-01	-3.14e-02	8.04e-01
GO:0034451 centriolar satellite	74	6.41e-01	3.14e-02	8.55e-01
GO:0007265 Ras protein signal transduction	37	7.44e-01	-3.11e-02	9.10e-01
GO:0009408 response to heat	19	8.15e-01	3.11e-02	9.40e-01
GO:0051056 regulation of small GTPase mediated signal transduction	16	8.30e-01	3.10e-02	9.43e-01
GO:0006882 intracellular zinc ion homeostasis	13	8.47e-01	3.10e-02	9.43e-01
GO:0019894 kinesin binding	22	8.02e-01	3.10e-02	9.35e-01
GO:0019901 protein kinase binding	236	4.15e-01	-3.09e-02	6.93e-01
GO:0071346 cellular response to type II interferon	24	7.93e-01	3.09e-02	9.31e-01
GO:0001558 regulation of cell growth	24	7.94e-01	-3.09e-02	9.31e-01
GO:0046856 phosphatidylinositol dephosphorylation	26	7.86e-01	-3.08e-02	9.26e-01
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	66	6.66e-01	-3.08e-02	8.67e-01
GO:0043596 nuclear replication fork	10	8.66e-01	3.08e-02	9.49e-01
GO:0001755 neural crest cell migration	27	7.83e-01	-3.06e-02	9.26e-01
GO:0005010 insulin-like growth factor receptor activity	15	8.38e-01	-3.05e-02	9.43e-01
GO:0045211 postsynaptic membrane	56	6.94e-01	-3.04e-02	8.85e-01
GO:0046676 negative regulation of insulin secretion	10	8.68e-01	-3.04e-02	9.49e-01
GO:0008045 motor neuron axon guidance	12	8.56e-01	-3.03e-02	9.44e-01
GO:0031032 actomyosin structure organization	18	8.25e-01	3.02e-02	9.43e-01
GO:0099170 postsynaptic modulation of chemical synaptic transmission	13	8.51e-01	3.02e-02	9.43e-01
GO:0048167 regulation of synaptic plasticity	16	8.35e-01	-3.01e-02	9.43e-01
GO:0006006 glucose metabolic process	26	7.91e-01	3.00e-02	9.30e-01
GO:0001530 lipopolysaccharide binding	11	8.64e-01	-2.99e-02	9.49e-01
GO:0036126 sperm flagellum	31	7.76e-01	-2.95e-02	9.26e-01
GO:0030217 T cell differentiation	18	8.30e-01	2.92e-02	9.43e-01
GO:0060021 roof of mouth development	35	7.66e-01	-2.91e-02	9.22e-01
GO:0005004 GPI-linked ephrin receptor activity	14	8.51e-01	-2.91e-02	9.43e-01
GO:0005007 fibroblast growth factor receptor activity	14	8.51e-01	-2.91e-02	9.43e-01
GO:0005011 macrophage colony-stimulating factor receptor activity	14	8.51e-01	-2.91e-02	9.43e-01
GO:0005018 platelet-derived growth factor alpha-receptor activity	14	8.51e-01	-2.91e-02	9.43e-01
GO:0005020 stem cell factor receptor activity	14	8.51e-01	-2.91e-02	9.43e-01
GO:0008288 boss receptor activity	14	8.51e-01	-2.91e-02	9.43e-01
GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway	14	8.51e-01	-2.91e-02	9.43e-01
GO:0036323 vascular endothelial growth factor receptor-1 signaling pathway	14	8.51e-01	-2.91e-02	9.43e-01
GO:0036332 placental growth factor receptor activity	14	8.51e-01	-2.91e-02	9.43e-01
GO:0038145 macrophage colony-stimulating factor signaling pathway	14	8.51e-01	-2.91e-02	9.43e-01
GO:0060175 brain-derived neurotrophic factor receptor activity	14	8.51e-01	-2.91e-02	9.43e-01
GO:0031547 brain-derived neurotrophic factor receptor signaling pathway	16	8.44e-01	2.85e-02	9.43e-01
GO:0009954 proximal/distal pattern formation	14	8.54e-01	-2.85e-02	9.44e-01
GO:0050853 B cell receptor signaling pathway	19	8.31e-01	-2.82e-02	9.43e-01
GO:0030901 midbrain development	11	8.71e-01	2.82e-02	9.49e-01
GO:0032755 positive regulation of interleukin-6 production	32	7.83e-01	-2.82e-02	9.26e-01
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process	155	5.49e-01	2.80e-02	8.02e-01
GO:0060271 cilium assembly	125	5.91e-01	-2.79e-02	8.25e-01
GO:0040029 epigenetic regulation of gene expression	18	8.38e-01	2.79e-02	9.43e-01
GO:0031594 neuromuscular junction	34	7.78e-01	-2.79e-02	9.26e-01
GO:0000082 G1/S transition of mitotic cell cycle	40	7.62e-01	-2.77e-02	9.20e-01
GO:0005737 cytoplasm	2179	4.15e-02	2.74e-02	2.13e-01
GO:0051894 positive regulation of focal adhesion assembly	15	8.55e-01	2.73e-02	9.44e-01
GO:0007283 spermatogenesis	101	6.36e-01	2.73e-02	8.54e-01
GO:0045453 bone resorption	12	8.70e-01	2.72e-02	9.49e-01
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	13	8.65e-01	2.71e-02	9.49e-01
GO:0097190 apoptotic signaling pathway	20	8.34e-01	2.71e-02	9.43e-01
GO:0008340 determination of adult lifespan	21	8.31e-01	-2.70e-02	9.43e-01
GO:0008286 insulin receptor signaling pathway	51	7.40e-01	2.69e-02	9.10e-01
GO:0035987 endodermal cell differentiation	21	8.32e-01	2.68e-02	9.43e-01
GO:0006400 tRNA modification	11	8.78e-01	-2.67e-02	9.52e-01
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity	16	8.54e-01	-2.66e-02	9.44e-01
GO:0015630 microtubule cytoskeleton	70	7.01e-01	-2.65e-02	8.89e-01
GO:0042130 negative regulation of T cell proliferation	12	8.74e-01	-2.64e-02	9.50e-01
GO:0050714 positive regulation of protein secretion	19	8.45e-01	2.60e-02	9.43e-01
GO:0008306 associative learning	11	8.82e-01	2.59e-02	9.53e-01
GO:0031625 ubiquitin protein ligase binding	172	5.62e-01	-2.57e-02	8.08e-01
GO:1990756 ubiquitin-like ligase-substrate adaptor activity	71	7.10e-01	-2.55e-02	8.94e-01
GO:0071480 cellular response to gamma radiation	14	8.69e-01	-2.55e-02	9.49e-01
GO:0016601 Rac protein signal transduction	17	8.56e-01	-2.55e-02	9.44e-01
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules	39	7.83e-01	2.55e-02	9.26e-01
GO:0042102 positive regulation of T cell proliferation	10	8.89e-01	2.55e-02	9.56e-01
GO:0071353 cellular response to interleukin-4	10	8.89e-01	2.54e-02	9.56e-01
GO:0007417 central nervous system development	41	7.79e-01	-2.53e-02	9.26e-01
GO:0010975 regulation of neuron projection development	16	8.62e-01	2.52e-02	9.48e-01
GO:0006509 membrane protein ectodomain proteolysis	15	8.66e-01	-2.51e-02	9.49e-01
GO:0019899 enzyme binding	110	6.53e-01	2.49e-02	8.62e-01
GO:0005164 tumor necrosis factor receptor binding	13	8.77e-01	-2.49e-02	9.51e-01
GO:0106310 protein serine kinase activity	38	7.91e-01	2.49e-02	9.30e-01
GO:0030426 growth cone	41	7.83e-01	2.49e-02	9.26e-01
GO:0043014 alpha-tubulin binding	23	8.38e-01	-2.46e-02	9.43e-01
GO:0003779 actin binding	143	6.15e-01	-2.44e-02	8.43e-01
GO:0001889 liver development	29	8.20e-01	2.44e-02	9.42e-01
GO:0006909 phagocytosis	22	8.43e-01	-2.44e-02	9.43e-01
GO:0031397 negative regulation of protein ubiquitination	33	8.09e-01	2.44e-02	9.39e-01
GO:0051959 dynein light intermediate chain binding	16	8.66e-01	2.44e-02	9.49e-01
GO:0051457 maintenance of protein location in nucleus	10	8.94e-01	2.43e-02	9.57e-01
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway	44	7.81e-01	2.43e-02	9.26e-01
GO:0030218 erythrocyte differentiation	27	8.30e-01	2.39e-02	9.43e-01
GO:0043025 neuronal cell body	87	7.01e-01	-2.38e-02	8.89e-01
GO:0043539 protein serine/threonine kinase activator activity	33	8.13e-01	2.38e-02	9.40e-01
GO:0016922 nuclear receptor binding	21	8.51e-01	-2.36e-02	9.44e-01
GO:1902476 chloride transmembrane transport	39	8.00e-01	-2.35e-02	9.35e-01
GO:0097191 extrinsic apoptotic signaling pathway	20	8.56e-01	-2.34e-02	9.44e-01
GO:0007409 axonogenesis	40	7.98e-01	-2.34e-02	9.34e-01
GO:0001822 kidney development	52	7.72e-01	-2.32e-02	9.25e-01
GO:1903078 positive regulation of protein localization to plasma membrane	23	8.47e-01	-2.32e-02	9.43e-01
GO:0050729 positive regulation of inflammatory response	22	8.51e-01	2.32e-02	9.43e-01
GO:0030336 negative regulation of cell migration	51	7.76e-01	2.31e-02	9.26e-01
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT	11	8.95e-01	2.30e-02	9.58e-01
GO:0031982 vesicle	27	8.40e-01	-2.25e-02	9.43e-01
GO:0050680 negative regulation of epithelial cell proliferation	25	8.46e-01	-2.25e-02	9.43e-01
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading	26	8.43e-01	-2.24e-02	9.43e-01
GO:0035019 somatic stem cell population maintenance	31	8.29e-01	-2.24e-02	9.43e-01
GO:0061744 motor behavior	16	8.79e-01	-2.20e-02	9.52e-01
GO:0098794 postsynapse	66	7.57e-01	-2.20e-02	9.17e-01
GO:0050918 positive chemotaxis	13	8.91e-01	2.20e-02	9.57e-01
GO:0005096 GTPase activator activity	153	6.40e-01	-2.20e-02	8.54e-01
GO:0048538 thymus development	21	8.62e-01	2.20e-02	9.48e-01
GO:0098685 Schaffer collateral - CA1 synapse	43	8.05e-01	-2.18e-02	9.37e-01
GO:0005635 nuclear envelope	77	7.42e-01	2.17e-02	9.10e-01
GO:0048027 mRNA 5’-UTR binding	19	8.70e-01	2.16e-02	9.49e-01
GO:0043010 camera-type eye development	22	8.61e-01	2.16e-02	9.48e-01
GO:0006654 phosphatidic acid biosynthetic process	12	8.97e-01	2.15e-02	9.59e-01
GO:0030178 negative regulation of Wnt signaling pathway	17	8.79e-01	-2.13e-02	9.52e-01
GO:1902894 negative regulation of miRNA transcription	12	8.99e-01	-2.12e-02	9.59e-01
GO:0008237 metallopeptidase activity	12	8.99e-01	-2.11e-02	9.59e-01
GO:0006955 immune response	42	8.15e-01	-2.09e-02	9.40e-01
GO:0004930 G protein-coupled receptor activity	58	7.84e-01	2.08e-02	9.26e-01
GO:0032731 positive regulation of interleukin-1 beta production	12	9.01e-01	-2.08e-02	9.60e-01
GO:0001726 ruffle	43	8.16e-01	2.06e-02	9.40e-01
GO:0046983 protein dimerization activity	69	7.69e-01	2.04e-02	9.25e-01
GO:0048018 receptor ligand activity	18	8.82e-01	-2.03e-02	9.53e-01
GO:0038062 protein tyrosine kinase collagen receptor activity	15	8.92e-01	2.02e-02	9.57e-01
GO:0032154 cleavage furrow	28	8.54e-01	-2.01e-02	9.44e-01
GO:0010468 regulation of gene expression	58	7.93e-01	-1.99e-02	9.31e-01
GO:0030027 lamellipodium	92	7.42e-01	1.99e-02	9.10e-01
GO:2000045 regulation of G1/S transition of mitotic cell cycle	18	8.86e-01	1.95e-02	9.56e-01
GO:0005802 trans-Golgi network	100	7.38e-01	-1.94e-02	9.09e-01
GO:0001917 photoreceptor inner segment	24	8.70e-01	-1.93e-02	9.49e-01
GO:0035329 hippo signaling	18	8.88e-01	-1.91e-02	9.56e-01
GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway	18	8.88e-01	1.91e-02	9.56e-01
GO:0051965 positive regulation of synapse assembly	23	8.74e-01	-1.91e-02	9.50e-01
GO:0051539 4 iron, 4 sulfur cluster binding	33	8.50e-01	1.90e-02	9.43e-01
GO:0002376 immune system process	12	9.10e-01	1.89e-02	9.62e-01
GO:2001235 positive regulation of apoptotic signaling pathway	17	8.93e-01	-1.88e-02	9.57e-01
GO:0007411 axon guidance	82	7.69e-01	-1.88e-02	9.25e-01
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway	14	9.04e-01	1.87e-02	9.60e-01
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	32	8.56e-01	-1.85e-02	9.44e-01
GO:0001666 response to hypoxia	50	8.21e-01	1.85e-02	9.42e-01
GO:0045216 cell-cell junction organization	13	9.08e-01	-1.85e-02	9.61e-01
GO:0043235 receptor complex	75	7.83e-01	1.84e-02	9.26e-01
GO:0051721 protein phosphatase 2A binding	14	9.05e-01	1.83e-02	9.60e-01
GO:0034707 chloride channel complex	12	9.13e-01	-1.83e-02	9.63e-01
GO:0005009 insulin receptor activity	16	9.00e-01	-1.82e-02	9.59e-01
GO:0045665 negative regulation of neuron differentiation	25	8.75e-01	-1.82e-02	9.51e-01
GO:0000226 microtubule cytoskeleton organization	69	7.94e-01	1.82e-02	9.31e-01
GO:0005923 bicellular tight junction	49	8.27e-01	1.81e-02	9.43e-01
GO:0048666 neuron development	26	8.74e-01	-1.80e-02	9.50e-01
GO:0090543 Flemming body	14	9.09e-01	1.77e-02	9.61e-01
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	28	8.72e-01	-1.76e-02	9.50e-01
GO:0004497 monooxygenase activity	12	9.16e-01	1.75e-02	9.66e-01
GO:0030177 positive regulation of Wnt signaling pathway	17	9.02e-01	-1.73e-02	9.60e-01
GO:0032722 positive regulation of chemokine production	12	9.18e-01	-1.72e-02	9.67e-01
GO:0045022 early endosome to late endosome transport	19	8.97e-01	1.72e-02	9.59e-01
GO:0048471 perinuclear region of cytoplasm	291	6.22e-01	1.69e-02	8.48e-01
GO:0043408 regulation of MAPK cascade	21	8.95e-01	1.66e-02	9.58e-01
GO:0030968 endoplasmic reticulum unfolded protein response	30	8.76e-01	1.65e-02	9.51e-01
GO:0071260 cellular response to mechanical stimulus	23	8.92e-01	-1.64e-02	9.57e-01
GO:0090398 cellular senescence	19	9.02e-01	1.62e-02	9.60e-01
GO:0005856 cytoskeleton	176	7.11e-01	-1.62e-02	8.94e-01
GO:0051879 Hsp90 protein binding	26	8.88e-01	1.59e-02	9.56e-01
GO:0042383 sarcolemma	36	8.69e-01	-1.58e-02	9.49e-01
GO:0071320 cellular response to cAMP	19	9.06e-01	1.57e-02	9.60e-01
GO:0015631 tubulin binding	28	8.87e-01	1.56e-02	9.56e-01
GO:0030425 dendrite	134	7.57e-01	-1.55e-02	9.17e-01
GO:0008654 phospholipid biosynthetic process	12	9.26e-01	-1.54e-02	9.75e-01
GO:0030674 protein-macromolecule adaptor activity	73	8.22e-01	-1.52e-02	9.42e-01
GO:0005516 calmodulin binding	69	8.33e-01	1.47e-02	9.43e-01
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding	12	9.30e-01	-1.46e-02	9.76e-01
GO:0034504 protein localization to nucleus	20	9.10e-01	1.45e-02	9.62e-01
GO:0090102 cochlea development	13	9.28e-01	1.45e-02	9.75e-01
GO:0034599 cellular response to oxidative stress	44	8.70e-01	-1.43e-02	9.49e-01
GO:0010629 negative regulation of gene expression	100	8.12e-01	-1.38e-02	9.40e-01
GO:0016791 phosphatase activity	15	9.27e-01	-1.36e-02	9.75e-01
GO:0001782 B cell homeostasis	12	9.37e-01	1.32e-02	9.78e-01
GO:0045787 positive regulation of cell cycle	13	9.35e-01	1.32e-02	9.76e-01
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment	35	8.93e-01	1.31e-02	9.57e-01
GO:0000242 pericentriolar material	14	9.32e-01	-1.31e-02	9.76e-01
GO:0043565 sequence-specific DNA binding	57	8.65e-01	-1.30e-02	9.49e-01
GO:0048041 focal adhesion assembly	14	9.34e-01	-1.28e-02	9.76e-01
GO:0031462 Cul2-RING ubiquitin ligase complex	15	9.32e-01	1.27e-02	9.76e-01
GO:0097550 transcription preinitiation complex	12	9.40e-01	-1.25e-02	9.79e-01
GO:0007268 chemical synaptic transmission	32	9.03e-01	1.25e-02	9.60e-01
GO:0007267 cell-cell signaling	13	9.38e-01	-1.24e-02	9.78e-01
GO:0006493 protein O-linked glycosylation	30	9.08e-01	1.22e-02	9.61e-01
GO:0048009 insulin-like growth factor receptor signaling pathway	33	9.04e-01	1.22e-02	9.60e-01
GO:0030496 midbody	99	8.34e-01	1.22e-02	9.43e-01
GO:0031175 neuron projection development	52	8.80e-01	1.21e-02	9.53e-01
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway	32	9.09e-01	-1.17e-02	9.61e-01
GO:0004860 protein kinase inhibitor activity	18	9.31e-01	-1.17e-02	9.76e-01
GO:0005852 eukaryotic translation initiation factor 3 complex	10	9.49e-01	1.17e-02	9.84e-01
GO:0046716 muscle cell cellular homeostasis	15	9.39e-01	1.15e-02	9.79e-01
GO:0099171 presynaptic modulation of chemical synaptic transmission	11	9.48e-01	1.14e-02	9.84e-01
GO:0035925 mRNA 3’-UTR AU-rich region binding	13	9.44e-01	-1.13e-02	9.81e-01
GO:0042056 chemoattractant activity	11	9.49e-01	1.11e-02	9.84e-01
GO:0051087 protein-folding chaperone binding	55	8.87e-01	1.11e-02	9.56e-01
GO:0005929 cilium	81	8.64e-01	1.10e-02	9.49e-01
GO:0098655 monoatomic cation transmembrane transport	14	9.44e-01	-1.09e-02	9.81e-01
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity	20	9.33e-01	1.08e-02	9.76e-01
GO:0090201 negative regulation of release of cytochrome c from mitochondria	11	9.52e-01	1.05e-02	9.84e-01
GO:0055038 recycling endosome membrane	43	9.05e-01	-1.05e-02	9.60e-01
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific	113	8.48e-01	1.04e-02	9.43e-01
GO:0038084 vascular endothelial growth factor signaling pathway	25	9.29e-01	-1.03e-02	9.75e-01
GO:0046329 negative regulation of JNK cascade	12	9.51e-01	-1.01e-02	9.84e-01
GO:0035556 intracellular signal transduction	185	8.13e-01	-1.01e-02	9.40e-01
GO:0016239 positive regulation of macroautophagy	17	9.45e-01	9.63e-03	9.82e-01
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway	19	9.43e-01	-9.49e-03	9.81e-01
GO:0051402 neuron apoptotic process	42	9.20e-01	-9.01e-03	9.69e-01
GO:0007052 mitotic spindle organization	34	9.31e-01	-8.55e-03	9.76e-01
GO:0005021 vascular endothelial growth factor receptor activity	17	9.51e-01	-8.54e-03	9.84e-01
GO:0042098 T cell proliferation	16	9.53e-01	-8.46e-03	9.85e-01
GO:0050772 positive regulation of axonogenesis	12	9.60e-01	8.39e-03	9.87e-01
GO:0045862 positive regulation of proteolysis	12	9.60e-01	8.35e-03	9.87e-01
GO:0042802 identical protein binding	661	7.19e-01	-8.28e-03	8.98e-01
GO:0050821 protein stabilization	109	8.82e-01	8.24e-03	9.53e-01
GO:0031252 cell leading edge	20	9.49e-01	-8.22e-03	9.84e-01
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	10	9.65e-01	-7.93e-03	9.90e-01
GO:0007162 negative regulation of cell adhesion	17	9.55e-01	7.93e-03	9.86e-01
GO:0030032 lamellipodium assembly	21	9.50e-01	7.88e-03	9.84e-01
GO:0032391 photoreceptor connecting cilium	19	9.55e-01	7.43e-03	9.86e-01
GO:0001678 intracellular glucose homeostasis	17	9.60e-01	7.02e-03	9.87e-01
GO:0030521 androgen receptor signaling pathway	12	9.67e-01	-6.84e-03	9.91e-01
GO:0070830 bicellular tight junction assembly	19	9.59e-01	6.82e-03	9.87e-01
GO:0043153 entrainment of circadian clock by photoperiod	13	9.66e-01	6.75e-03	9.90e-01
GO:0048706 embryonic skeletal system development	16	9.63e-01	-6.65e-03	9.89e-01
GO:0006367 transcription initiation at RNA polymerase II promoter	20	9.59e-01	-6.60e-03	9.87e-01
GO:0004725 protein tyrosine phosphatase activity	44	9.43e-01	-6.21e-03	9.81e-01
GO:0031410 cytoplasmic vesicle	107	9.13e-01	-6.13e-03	9.63e-01
GO:0005525 GTP binding	212	8.82e-01	-5.91e-03	9.53e-01
GO:0005911 cell-cell junction	77	9.29e-01	-5.90e-03	9.75e-01
GO:0002244 hematopoietic progenitor cell differentiation	34	9.56e-01	-5.44e-03	9.86e-01
GO:0045672 positive regulation of osteoclast differentiation	11	9.76e-01	-5.22e-03	9.97e-01
GO:0042472 inner ear morphogenesis	26	9.64e-01	5.18e-03	9.89e-01
GO:0001525 angiogenesis	86	9.35e-01	-5.07e-03	9.77e-01
GO:0017025 TBP-class protein binding	18	9.70e-01	5.04e-03	9.92e-01
GO:0071549 cellular response to dexamethasone stimulus	11	9.78e-01	4.88e-03	9.97e-01
GO:0004197 cysteine-type endopeptidase activity	37	9.61e-01	4.63e-03	9.87e-01
GO:0051219 phosphoprotein binding	20	9.73e-01	4.35e-03	9.94e-01
GO:0008284 positive regulation of cell population proliferation	156	9.28e-01	4.20e-03	9.75e-01
GO:0051131 chaperone-mediated protein complex assembly	14	9.79e-01	4.09e-03	9.97e-01
GO:0007420 brain development	78	9.58e-01	3.47e-03	9.87e-01
GO:0140627 ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	10	9.85e-01	3.44e-03	9.97e-01
GO:0003281 ventricular septum development	15	9.82e-01	3.33e-03	9.97e-01
GO:0019955 cytokine binding	11	9.85e-01	-3.22e-03	9.97e-01
GO:0051019 mitogen-activated protein kinase binding	11	9.85e-01	-3.18e-03	9.97e-01
GO:0050699 WW domain binding	11	9.86e-01	-3.13e-03	9.97e-01
GO:0004222 metalloendopeptidase activity	50	9.70e-01	-3.12e-03	9.92e-01
GO:0070412 R-SMAD binding	13	9.86e-01	2.85e-03	9.97e-01
GO:0006898 receptor-mediated endocytosis	24	9.81e-01	-2.79e-03	9.97e-01
GO:0003755 peptidyl-prolyl cis-trans isomerase activity	30	9.79e-01	2.77e-03	9.97e-01
GO:0050727 regulation of inflammatory response	26	9.81e-01	-2.71e-03	9.97e-01
GO:0097546 ciliary base	17	9.85e-01	-2.71e-03	9.97e-01
GO:0000124 SAGA complex	15	9.86e-01	-2.57e-03	9.97e-01
GO:0006986 response to unfolded protein	12	9.89e-01	-2.26e-03	9.97e-01
GO:0055037 recycling endosome	55	9.77e-01	-2.26e-03	9.97e-01
GO:0043065 positive regulation of apoptotic process	122	9.70e-01	-2.01e-03	9.92e-01
GO:0050796 regulation of insulin secretion	12	9.91e-01	1.97e-03	9.97e-01
GO:0050728 negative regulation of inflammatory response	49	9.82e-01	-1.81e-03	9.97e-01
GO:0031593 polyubiquitin modification-dependent protein binding	19	9.89e-01	1.78e-03	9.97e-01
GO:0000175 3’-5’-RNA exonuclease activity	21	9.89e-01	1.72e-03	9.97e-01
GO:0031398 positive regulation of protein ubiquitination	40	9.85e-01	-1.68e-03	9.97e-01
GO:0030317 flagellated sperm motility	29	9.88e-01	1.63e-03	9.97e-01
GO:0034446 substrate adhesion-dependent cell spreading	34	9.87e-01	1.61e-03	9.97e-01
GO:0098793 presynapse	63	9.83e-01	1.57e-03	9.97e-01
GO:0031464 Cul4A-RING E3 ubiquitin ligase complex	10	9.94e-01	1.48e-03	9.98e-01
GO:0030659 cytoplasmic vesicle membrane	43	9.87e-01	-1.47e-03	9.97e-01
GO:0008327 methyl-CpG binding	16	9.92e-01	-1.45e-03	9.98e-01
GO:0019722 calcium-mediated signaling	31	9.89e-01	-1.42e-03	9.97e-01
GO:0030307 positive regulation of cell growth	36	9.91e-01	1.05e-03	9.98e-01
GO:0071479 cellular response to ionizing radiation	22	9.95e-01	-7.72e-04	9.99e-01
GO:0000281 mitotic cytokinesis	34	9.94e-01	-7.67e-04	9.98e-01
GO:0005262 calcium channel activity	21	9.96e-01	5.87e-04	9.99e-01
GO:0005774 vacuolar membrane	10	9.98e-01	5.43e-04	9.99e-01
GO:1905515 non-motile cilium assembly	39	9.96e-01	4.49e-04	9.99e-01
GO:0030183 B cell differentiation	26	9.97e-01	-4.02e-04	9.99e-01
GO:0030155 regulation of cell adhesion	18	9.98e-01	-3.87e-04	9.99e-01
GO:0035269 protein O-linked mannosylation	13	9.99e-01	1.77e-04	1.00e+00
GO:0009617 response to bacterium	36	1.00e+00	-2.32e-05	1.00e+00

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Detailed Gene set reports

GO:0045943 positive regulation of transcription by RNA polymerase I

set	GO:0045943 positive regulation of transcription by RNA polymerase I
setSize	11
pANOVA	7.55e-07
s.dist	0.861
p.adjustANOVA	5.35e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ATF4	7135
UBTF	7074
HEATR1	7073
UTP15	6341
WDR75	6168
EIF2AK3	6062
ERBB2	5994
DHX33	5880
WDR43	5582
BNC1	5548
LYAR	5380

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ATF4	7135
UBTF	7074
HEATR1	7073
UTP15	6341
WDR75	6168
EIF2AK3	6062
ERBB2	5994
DHX33	5880
WDR43	5582
BNC1	5548
LYAR	5380

---

GO:0005049 nuclear export signal receptor activity

set	GO:0005049 nuclear export signal receptor activity
setSize	10
pANOVA	1.12e-05
s.dist	0.802
p.adjustANOVA	0.000521

Top enriched genes

Top 20 genes

GeneID	Gene Rank
XPO5	7041
NUP214	6964
XPO1	6602
XPO6	6349
XPO4	6182
NUP42	5608
XPO7	5257
CALR	5076
CSE1L	4934
EIF4ENIF1	3785

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
XPO5	7041
NUP214	6964
XPO1	6602
XPO6	6349
XPO4	6182
NUP42	5608
XPO7	5257
CALR	5076
CSE1L	4934
EIF4ENIF1	3785

---

GO:0140662 ATP-dependent protein folding chaperone

set	GO:0140662 ATP-dependent protein folding chaperone
setSize	23
pANOVA	4.59e-10
s.dist	0.75
p.adjustANOVA	7.4e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HSPA2	7180
HSP90AA1	7179
HSPD1	7063
HSPA8	6826
HYOU1	6799
HSPA4L	6663
HSP90B1	6574
CCT4	6526
HSPH1	6499
HSPA5	6431
HSPA13	6410
HSPA4	6314
TCP1	6291
CCT2	5884
CCT7	5630
HSPA9	4935
CCT5	4670
CCT3	4513
CCT8	3440
TRAP1	2991

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HSPA2	7180
HSP90AA1	7179
HSPD1	7063
HSPA8	6826
HYOU1	6799
HSPA4L	6663
HSP90B1	6574
CCT4	6526
HSPH1	6499
HSPA5	6431
HSPA13	6410
HSPA4	6314
TCP1	6291
CCT2	5884
CCT7	5630
HSPA9	4935
CCT5	4670
CCT3	4513
CCT8	3440
TRAP1	2991
HSPA14	2739
TOR1A	1573
CLPX	1155

---

GO:0022627 cytosolic small ribosomal subunit

set	GO:0022627 cytosolic small ribosomal subunit
setSize	25
pANOVA	1.87e-10
s.dist	-0.736
p.adjustANOVA	3.68e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS29	-7006
RPS14	-6984
RPS3	-6932
RPS3A	-6885
RPS15	-6843
RPS2	-6836
RPS23	-6833
RPS12	-6748
RPS6	-6745
RPS15A	-6660
RPS11	-6625
RPS24	-6582
RPS4Y1	-6553
RPS20	-6526
RPS16	-6508
RPS21	-6432
RPS26	-6426
RPS28	-6376
RPS7	-6201
RPS13	-5788

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS29	-7006
RPS14	-6984
RPS3	-6932
RPS3A	-6885
RPS15	-6843
RPS2	-6836
RPS23	-6833
RPS12	-6748
RPS6	-6745
RPS15A	-6660
RPS11	-6625
RPS24	-6582
RPS4Y1	-6553
RPS20	-6526
RPS16	-6508
RPS21	-6432
RPS26	-6426
RPS28	-6376
RPS7	-6201
RPS13	-5788
RPS8	-5422
RPS10	-1535
RPS27L	314
EIF2A	633
LARP4	6859

---

GO:0022625 cytosolic large ribosomal subunit

set	GO:0022625 cytosolic large ribosomal subunit
setSize	40
pANOVA	2.85e-15
s.dist	-0.721
p.adjustANOVA	1.69e-12

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL31	-6832
RPL29	-6801
RPL13	-6773
RPL15	-6722
RPL35A	-6692
RPL35	-6687
RPLP0	-6588
RPL34	-6538
RPL30	-6534
RPL7A	-6531
RPLP1	-6503
RPL10A	-6476
RPL9	-6358
RPL8	-6345
RPL38	-6315
RPL37	-6309
RPL4	-6269
RPL14	-6241
RPL3	-6234
RPL37A	-6217

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL31	-6832
RPL29	-6801
RPL13	-6773
RPL15	-6722
RPL35A	-6692
RPL35	-6687
RPLP0	-6588
RPL34	-6538
RPL30	-6534
RPL7A	-6531
RPLP1	-6503
RPL10A	-6476
RPL9	-6358
RPL8	-6345
RPL38	-6315
RPL37	-6309
RPL4	-6269
RPL14	-6241
RPL3	-6234
RPL37A	-6217
RPL26L1	-6194
RPL32	-6168
RPL24	-6093
RPL27A	-6061
RPL7L1	-5891
RPL5	-5675
RPLP2	-5616
RPL23A	-5125
RPL18A	-5043
RPL7	-5002
RPL23	-4181
RPL12	-3658
RPL27	-3589
RPL11	-2967
RPL21	-2864
RPL6	-2412
RPL36	-2317
RPL3L	-2071
RPL19	-1367
ZCCHC17	6082

---

GO:0035145 exon-exon junction complex

set	GO:0035145 exon-exon junction complex
setSize	10
pANOVA	7.85e-05
s.dist	0.721
p.adjustANOVA	0.00258

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PNN	7061
SMG6	6542
UPF2	6015
SRSF1	5709
UPF3B	5406
THRAP3	5054
UPF1	4616
CASC3	4540
TDRD3	4072
UPF3A	2961

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PNN	7061
SMG6	6542
UPF2	6015
SRSF1	5709
UPF3B	5406
THRAP3	5054
UPF1	4616
CASC3	4540
TDRD3	4072
UPF3A	2961

---

GO:0070034 telomerase RNA binding

set	GO:0070034 telomerase RNA binding
setSize	12
pANOVA	2.43e-05
s.dist	0.704
p.adjustANOVA	0.000896

Top enriched genes

Top 20 genes

GeneID	Gene Rank
DKC1	6904
PARN	6811
HNRNPU	6768
SMG6	6542
GAR1	6493
SMG7	6376
SMG5	6212
NAF1	5943
EXOSC10	5716
XRN1	2389
PINX1	708
DHX36	1

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
DKC1	6904
PARN	6811
HNRNPU	6768
SMG6	6542
GAR1	6493
SMG7	6376
SMG5	6212
NAF1	5943
EXOSC10	5716
XRN1	2389
PINX1	708
DHX36	1

---

GO:0000228 nuclear chromosome

set	GO:0000228 nuclear chromosome
setSize	13
pANOVA	1.62e-05
s.dist	0.69
p.adjustANOVA	0.000685

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TOP1	7122
SMC2	6908
ATRX	6888
HNRNPU	6768
BAZ1A	6727
SETX	6099
NCAPD2	5655
EXOSC9	5456
SPO11	4969
IK	4439
SMARCB1	4087
PINX1	708
FIGNL1	-1130

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TOP1	7122
SMC2	6908
ATRX	6888
HNRNPU	6768
BAZ1A	6727
SETX	6099
NCAPD2	5655
EXOSC9	5456
SPO11	4969
IK	4439
SMARCB1	4087
PINX1	708
FIGNL1	-1130

---

GO:0003678 DNA helicase activity

set	GO:0003678 DNA helicase activity
setSize	20
pANOVA	9.56e-08
s.dist	0.689
p.adjustANOVA	7.36e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RTEL1	7013
TWNK	6956
DNA2	6809
MCM4	6654
MCM6	6448
XRCC6	6403
MRE11	6278
MCM9	6167
BRIP1	6145
RAD50	6104
G3BP1	6100
RUVBL1	5624
XRCC5	5519
CHD1L	5273
DDX11	4991
RECQL5	3702
DHX30	3263
SNRNP200	1171
DHX36	1
SUPV3L1	-1360

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RTEL1	7013
TWNK	6956
DNA2	6809
MCM4	6654
MCM6	6448
XRCC6	6403
MRE11	6278
MCM9	6167
BRIP1	6145
RAD50	6104
G3BP1	6100
RUVBL1	5624
XRCC5	5519
CHD1L	5273
DDX11	4991
RECQL5	3702
DHX30	3263
SNRNP200	1171
DHX36	1
SUPV3L1	-1360

---

GO:0036121 double-stranded DNA helicase activity

set	GO:0036121 double-stranded DNA helicase activity
setSize	11
pANOVA	8.29e-05
s.dist	0.685
p.adjustANOVA	0.00262

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	6956
ERCC3	6757
BLM	6598
CHD7	6521
MCM9	6167
MCM8	5563
MCM5	5372
UPF1	4616
MCM3	3675
IGHMBP2	2059
CHD1	55

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	6956
ERCC3	6757
BLM	6598
CHD7	6521
MCM9	6167
MCM8	5563
MCM5	5372
UPF1	4616
MCM3	3675
IGHMBP2	2059
CHD1	55

---

GO:0002181 cytoplasmic translation

set	GO:0002181 cytoplasmic translation
setSize	27
pANOVA	9.38e-10
s.dist	-0.68
p.adjustANOVA	1.38e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS29	-7006
RPS14	-6984
RPS23	-6833
RPL31	-6832
RPL29	-6801
SARS1	-6779
RPS6	-6745
RPL15	-6722
RPL35A	-6692
RPLP0	-6588
RPLP1	-6503
RPL10A	-6476
RPS26	-6426
RPS28	-6376
RPL9	-6358
RPL8	-6345
RPL38	-6315
RPL26L1	-6194
RPL24	-6093
RPL22	-5990

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS29	-7006
RPS14	-6984
RPS23	-6833
RPL31	-6832
RPL29	-6801
SARS1	-6779
RPS6	-6745
RPL15	-6722
RPL35A	-6692
RPLP0	-6588
RPLP1	-6503
RPL10A	-6476
RPS26	-6426
RPS28	-6376
RPL9	-6358
RPL8	-6345
RPL38	-6315
RPL26L1	-6194
RPL24	-6093
RPL22	-5990
RPL18A	-5043
RPL6	-2412
RPL36	-2317
RWDD1	-1596
DRG2	2511
RPL22L1	2525
ZC3H15	6032

---

GO:1990518 single-stranded 3’-5’ DNA helicase activity

set	GO:1990518 single-stranded 3’-5’ DNA helicase activity
setSize	11
pANOVA	0.000111
s.dist	0.673
p.adjustANOVA	0.00339

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	6956
ERCC3	6757
BLM	6598
CHD7	6521
MCM6	6448
MCM9	6167
MCM8	5563
MCM5	5372
MCM3	3675
CHD1	55
HELQ	-746

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	6956
ERCC3	6757
BLM	6598
CHD7	6521
MCM6	6448
MCM9	6167
MCM8	5563
MCM5	5372
MCM3	3675
CHD1	55
HELQ	-746

---

GO:0000245 spliceosomal complex assembly

set	GO:0000245 spliceosomal complex assembly
setSize	10
pANOVA	0.000552
s.dist	0.631
p.adjustANOVA	0.0121

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SCAF11	6982
SF3B1	6315
RSRP1	5923
USP39	5281
SRPK2	4887
RBM10	4882
SF3A2	3629
SRPK1	3427
PRPF19	2515
ZRSR2	1649

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SCAF11	6982
SF3B1	6315
RSRP1	5923
USP39	5281
SRPK2	4887
RBM10	4882
SF3A2	3629
SRPK1	3427
PRPF19	2515
ZRSR2	1649

---

GO:0043627 response to estrogen

set	GO:0043627 response to estrogen
setSize	10
pANOVA	0.000653
s.dist	0.622
p.adjustANOVA	0.0137

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GATA6	7009
RBBP5	7008
TRIM25	6330
CAV1	5997
ASH2L	5828
EP300	5104
KMT2D	5005
GHRL	3754
SLC34A2	1802
PGR	-2948

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GATA6	7009
RBBP5	7008
TRIM25	6330
CAV1	5997
ASH2L	5828
EP300	5104
KMT2D	5005
GHRL	3754
SLC34A2	1802
PGR	-2948

---

GO:0002230 positive regulation of defense response to virus by host

set	GO:0002230 positive regulation of defense response to virus by host
setSize	11
pANOVA	0.000456
s.dist	0.61
p.adjustANOVA	0.0103

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HSP90AA1	7179
ZC3H12A	7086
PARP9	6563
DTX3L	6476
SIN3A	6018
STAT1	5903
ZDHHC1	5260
IL12B	4444
TOMM70	1971
SELENOK	-786
TMEM173	-1697

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HSP90AA1	7179
ZC3H12A	7086
PARP9	6563
DTX3L	6476
SIN3A	6018
STAT1	5903
ZDHHC1	5260
IL12B	4444
TOMM70	1971
SELENOK	-786
TMEM173	-1697

---

GO:0061749 forked DNA-dependent helicase activity

set	GO:0061749 forked DNA-dependent helicase activity
setSize	10
pANOVA	0.000941
s.dist	0.604
p.adjustANOVA	0.0179

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	6956
ERCC3	6757
BLM	6598
CHD7	6521
MCM9	6167
MCM8	5563
MCM5	5372
MCM3	3675
CHD1	55
WRN	-4101

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	6956
ERCC3	6757
BLM	6598
CHD7	6521
MCM9	6167
MCM8	5563
MCM5	5372
MCM3	3675
CHD1	55
WRN	-4101

---

GO:0032212 positive regulation of telomere maintenance via telomerase

set	GO:0032212 positive regulation of telomere maintenance via telomerase
setSize	17
pANOVA	1.72e-05
s.dist	0.602
p.adjustANOVA	0.000695

Top enriched genes

Top 20 genes

GeneID	Gene Rank
DKC1	6904
PARN	6811
CCT4	6526
TCP1	6291
NEK7	6086
NAF1	5943
CCT2	5884
CCT7	5630
HNRNPD	5003
CCT5	4670
CTNNB1	4571
CCT3	4513
CCT8	3440
POT1	3296
TNKS	1436
PTGES3	933
PKIB	-4152

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
DKC1	6904
PARN	6811
CCT4	6526
TCP1	6291
NEK7	6086
NAF1	5943
CCT2	5884
CCT7	5630
HNRNPD	5003
CCT5	4670
CTNNB1	4571
CCT3	4513
CCT8	3440
POT1	3296
TNKS	1436
PTGES3	933
PKIB	-4152

---

GO:0000793 condensed chromosome

set	GO:0000793 condensed chromosome
setSize	13
pANOVA	0.000195
s.dist	0.597
p.adjustANOVA	0.00541

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BAZ1B	7058
RIF1	7047
SMC2	6908
TOP2A	6554
TOP3B	6432
SMARCA5	6371
HMGB2	5807
NCAPD2	5655
FANCD2	4921
CTCF	4905
NCAPG	1403
CDK2	-3476
LIG4	-3650

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BAZ1B	7058
RIF1	7047
SMC2	6908
TOP2A	6554
TOP3B	6432
SMARCA5	6371
HMGB2	5807
NCAPD2	5655
FANCD2	4921
CTCF	4905
NCAPG	1403
CDK2	-3476
LIG4	-3650

---

GO:0017056 structural constituent of nuclear pore

set	GO:0017056 structural constituent of nuclear pore
setSize	19
pANOVA	1.02e-05
s.dist	0.585
p.adjustANOVA	0.000488

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NUP155	6996
TPR	6976
NUP214	6964
NUP205	6865
NUP160	6838
NUP153	6541
NUP107	6299
NUP188	6147
NDC1	6111
NUP98	6101
NUP133	5450
NUP62	5161
NUP35	3004
NUP54	2644
NUP85	2632
NUP88	-489
NUTF2	-722
NUP58	-1229
NUP93	-2192

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NUP155	6996
TPR	6976
NUP214	6964
NUP205	6865
NUP160	6838
NUP153	6541
NUP107	6299
NUP188	6147
NDC1	6111
NUP98	6101
NUP133	5450
NUP62	5161
NUP35	3004
NUP54	2644
NUP85	2632
NUP88	-489
NUTF2	-722
NUP58	-1229
NUP93	-2192

---

GO:0007249 canonical NF-kappaB signal transduction

set	GO:0007249 canonical NF-kappaB signal transduction
setSize	18
pANOVA	2.14e-05
s.dist	0.579
p.adjustANOVA	0.00081

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ADAM8	7152
NFKB2	7043
REL	6989
CREBBP	6862
TRADD	6688
ABL1	6650
CARD11	6107
RIPK2	6092
TRIM8	5896
MAP3K7	5718
IRAK2	5280
EP300	5104
MAP3K14	4794
NFKB1	4602
NLRC3	3370
TRAF6	-1854
IFT80	-5185
RASSF2	-6235

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ADAM8	7152
NFKB2	7043
REL	6989
CREBBP	6862
TRADD	6688
ABL1	6650
CARD11	6107
RIPK2	6092
TRIM8	5896
MAP3K7	5718
IRAK2	5280
EP300	5104
MAP3K14	4794
NFKB1	4602
NLRC3	3370
TRAF6	-1854
IFT80	-5185
RASSF2	-6235

---

GO:0042026 protein refolding

set	GO:0042026 protein refolding
setSize	12
pANOVA	0.000742
s.dist	0.562
p.adjustANOVA	0.0153

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HSPA2	7180
HSPD1	7063
DNAJA1	7002
HSPA8	6826
DNAJA4	6559
HSPA5	6431
HSPA13	6410
HSPA9	4935
HSPA14	2739
DNAJA2	1461
HSPB1	-2452
DNAJB2	-5469

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HSPA2	7180
HSPD1	7063
DNAJA1	7002
HSPA8	6826
DNAJA4	6559
HSPA5	6431
HSPA13	6410
HSPA9	4935
HSPA14	2739
DNAJA2	1461
HSPB1	-2452
DNAJB2	-5469

---

GO:0009378 four-way junction helicase activity

set	GO:0009378 four-way junction helicase activity
setSize	13
pANOVA	0.000455
s.dist	0.562
p.adjustANOVA	0.0103

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	6956
ERCC3	6757
BLM	6598
CHD7	6521
MCM9	6167
FANCM	5646
MCM8	5563
MCM5	5372
RECQL5	3702
MCM3	3675
CHD1	55
RECQL	-251
WRN	-4101

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	6956
ERCC3	6757
BLM	6598
CHD7	6521
MCM9	6167
FANCM	5646
MCM8	5563
MCM5	5372
RECQL5	3702
MCM3	3675
CHD1	55
RECQL	-251
WRN	-4101

---

GO:1990391 DNA repair complex

set	GO:1990391 DNA repair complex
setSize	10
pANOVA	0.0024
s.dist	0.554
p.adjustANOVA	0.0346

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FANCI	6878
BRCA1	6649
TP53BP1	6631
ATM	6456
FANCD2	4921
BRCA2	2928
PALB2	2920
KDM1A	2259
ASCC2	1252
PHF21A	-899

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FANCI	6878
BRCA1	6649
TP53BP1	6631
ATM	6456
FANCD2	4921
BRCA2	2928
PALB2	2920
KDM1A	2259
ASCC2	1252
PHF21A	-899

---

GO:0030199 collagen fibril organization

set	GO:0030199 collagen fibril organization
setSize	32
pANOVA	6.37e-08
s.dist	-0.552
p.adjustANOVA	5.64e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
COL6A1	-7137
COL1A2	-7108
COL5A1	-7066
COL5A2	-7060
PLOD1	-7050
COL1A1	-7046
EXT1	-7044
FKBP10	-7030
DPT	-7025
ADAMTS2	-6769
P3H4	-6731
PXDN	-6683
CDH11	-6344
VPS33B	-5848
ADAMTS12	-5715
SERPINH1	-5557
P4HA3	-5147
CRTAP	-4653
TGFB2	-4633
LOXL3	-4541

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
COL6A1	-7137
COL1A2	-7108
COL5A1	-7066
COL5A2	-7060
PLOD1	-7050
COL1A1	-7046
EXT1	-7044
FKBP10	-7030
DPT	-7025
ADAMTS2	-6769
P3H4	-6731
PXDN	-6683
CDH11	-6344
VPS33B	-5848
ADAMTS12	-5715
SERPINH1	-5557
P4HA3	-5147
CRTAP	-4653
TGFB2	-4633
LOXL3	-4541
LOXL4	-4494
LOX	-3881
COL14A1	-3729
ERO1A	-3466
SERPINF2	-2790
COL11A1	-1590
P4HA1	-1263
ADAMTS14	-408
VIPAS39	4705
PLOD2	5010
DDR2	5124
LOXL2	6697

---

GO:0007004 telomere maintenance via telomerase

set	GO:0007004 telomere maintenance via telomerase
setSize	11
pANOVA	0.00152
s.dist	0.552
p.adjustANOVA	0.0247

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HSP90AA1	7179
DKC1	6904
GAR1	6493
RAD50	6104
XRCC5	5519
RPA1	4176
POT1	3296
HMBOX1	2984
PTGES3	933
PINX1	708
TERF1	-485

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HSP90AA1	7179
DKC1	6904
GAR1	6493
RAD50	6104
XRCC5	5519
RPA1	4176
POT1	3296
HMBOX1	2984
PTGES3	933
PINX1	708
TERF1	-485

---

GO:0007042 lysosomal lumen acidification

set	GO:0007042 lysosomal lumen acidification
setSize	10
pANOVA	0.00263
s.dist	-0.549
p.adjustANOVA	0.0367

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CREG1	-7021
CLN6	-6926
TMEM106B	-6535
LAMP2	-6510
PPT1	-4291
ATP6AP2	-3424
TMEM9	-2811
LAMP1	-2405
TMEM199	-618
CLN5	1239

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CREG1	-7021
CLN6	-6926
TMEM106B	-6535
LAMP2	-6510
PPT1	-4291
ATP6AP2	-3424
TMEM9	-2811
LAMP1	-2405
TMEM199	-618
CLN5	1239

---

GO:0016581 NuRD complex

set	GO:0016581 NuRD complex
setSize	10
pANOVA	0.00296
s.dist	0.543
p.adjustANOVA	0.0402

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RBBP4	6748
CHD4	6684
GATAD2B	6392
MTA2	6275
MTA1	5885
CHD5	3455
RBBP7	1888
GATAD2A	821
HDAC1	818
HDAC2	197

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RBBP4	6748
CHD4	6684
GATAD2B	6392
MTA2	6275
MTA1	5885
CHD5	3455
RBBP7	1888
GATAD2A	821
HDAC1	818
HDAC2	197

---

GO:0004364 glutathione transferase activity

set	GO:0004364 glutathione transferase activity
setSize	10
pANOVA	0.00297
s.dist	-0.542
p.adjustANOVA	0.0402

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MGST1	-6956
GSTO2	-6568
HPGDS	-6314
GSTM2	-6200
MGST3	-6124
GSTT1	-5053
GSTZ1	-4456
LANCL1	-3268
GSTK1	472
PTGES	5654

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MGST1	-6956
GSTO2	-6568
HPGDS	-6314
GSTM2	-6200
MGST3	-6124
GSTT1	-5053
GSTZ1	-4456
LANCL1	-3268
GSTK1	472
PTGES	5654

---

GO:0070577 lysine-acetylated histone binding

set	GO:0070577 lysine-acetylated histone binding
setSize	16
pANOVA	0.000193
s.dist	0.538
p.adjustANOVA	0.00541

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BRD2	7161
PHIP	6619
MLLT1	6553
PSME4	6473
ZZEF1	5856
KMT2A	5677
TRIM24	5585
DPF2	5544
ZMYND8	5442
ATAD2B	4768
BRPF3	4131
BRD9	3513
BRD7	1702
BRD3	923
ZZZ3	-2529
MLLT3	-5296

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BRD2	7161
PHIP	6619
MLLT1	6553
PSME4	6473
ZZEF1	5856
KMT2A	5677
TRIM24	5585
DPF2	5544
ZMYND8	5442
ATAD2B	4768
BRPF3	4131
BRD9	3513
BRD7	1702
BRD3	923
ZZZ3	-2529
MLLT3	-5296

---

GO:0061775 cohesin loader activity

set	GO:0061775 cohesin loader activity
setSize	24
pANOVA	8.19e-06
s.dist	0.526
p.adjustANOVA	0.000427

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	6956
DDX6	6873
DNA2	6809
ERCC3	6757
BLM	6598
CHD7	6521
HSPA5	6431
MCM9	6167
BRIP1	6145
FANCM	5646
MCM8	5563
DDX42	5426
DDX10	5253
PMS2	4265
MAU2	4187
MCM3	3675
DHX30	3263
MOV10	1740
DDX55	913
CHD1	55

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	6956
DDX6	6873
DNA2	6809
ERCC3	6757
BLM	6598
CHD7	6521
HSPA5	6431
MCM9	6167
BRIP1	6145
FANCM	5646
MCM8	5563
DDX42	5426
DDX10	5253
PMS2	4265
MAU2	4187
MCM3	3675
DHX30	3263
MOV10	1740
DDX55	913
CHD1	55
DDX1	-715
SUPV3L1	-1360
EIF4A3	-1787
EIF4A2	-4382

---

GO:0003735 structural constituent of ribosome

set	GO:0003735 structural constituent of ribosome
setSize	118
pANOVA	8.72e-23
s.dist	-0.524
p.adjustANOVA	1.55e-19

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MRPS31	-7069
RPS29	-7006
RPS14	-6984
RPS3	-6932
RPS17	-6928
RPS3A	-6885
RPS15	-6843
RPS2	-6836
RPS23	-6833
RPL31	-6832
MRPL37	-6802
RPL29	-6801
RPL13	-6773
RPS12	-6748
RPS6	-6745
RPL15	-6722
RPL35A	-6692
RPL35	-6687
MRPL36	-6663
RPS15A	-6660

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MRPS31	-7069
RPS29	-7006
RPS14	-6984
RPS3	-6932
RPS17	-6928
RPS3A	-6885
RPS15	-6843
RPS2	-6836
RPS23	-6833
RPL31	-6832
MRPL37	-6802
RPL29	-6801
RPL13	-6773
RPS12	-6748
RPS6	-6745
RPL15	-6722
RPL35A	-6692
RPL35	-6687
MRPL36	-6663
RPS15A	-6660
RPS11	-6625
MRPS21	-6603
RPLP0	-6588
RPS24	-6582
RPS4Y1	-6553
RPL34	-6538
RPL30	-6534
RPS20	-6526
RPS16	-6508
RPLP1	-6503
RPL10A	-6476
RPS21	-6432
RPS26	-6426
RPS28	-6376
RPL9	-6358
RPL8	-6345
RPL38	-6315
RPL37	-6309
MRPL13	-6281
RPL4	-6269
RPL14	-6241
RPL3	-6234
RPL37A	-6217
RPS7	-6201
RPL26L1	-6194
RPL32	-6168
MRPL23	-6153
MRPS11	-6126
RPL24	-6093
RPL27A	-6061
RPL22	-5990
MRPL17	-5899
RPL7L1	-5891
RPS27A	-5810
RPS13	-5788
RPL5	-5675
RPLP2	-5616
MRPL2	-5610
MRPL16	-5485
RPS8	-5422
MRPL51	-5386
MRPL35	-5351
MRPS23	-5131
RPL23A	-5125
MRPS34	-5098
RPL18A	-5043
MRPS17	-5009
RPL7	-5002
MRPS12	-4415
MRPL27	-4236
RPL23	-4181
MRPL32	-4151
MRPL19	-4146
MRPL41	-3826
UBA52	-3688
RPL12	-3658
RPL27	-3589
MRPL18	-3439
DDA1	-3170
MRPL28	-2977
RPL11	-2967
MRPL12	-2888
RPL21	-2864
MRPL14	-2479
RPL6	-2412
RPL36	-2317
MRPS16	-2275
RPL3L	-2071
MRPL24	-1883
RPS10	-1535
RPL19	-1367
MRPS18C	-1318
MRPS15	-946
MRPL22	-756
MRPS25	-501
MRPL49	88
MRPS30	294
RPS27L	314
MRPS6	641
MRPS14	1477
MRPL21	1501
MRPL10	1694
MRPS22	1967
DAP3	2033
SRBD1	2350
RPL22L1	2525
MRPL47	2621
MRPS10	2790
MRPS7	2830
MRPS35	3253
MRPS18A	3406
MRPS9	3419
MRPS2	3534
MRPL3	4520
MRPL15	4590
MRPL46	4736
MRPL20	5226
MRPS5	5250

---

GO:0140584 chromatin extrusion motor activity

set	GO:0140584 chromatin extrusion motor activity
setSize	23
pANOVA	1.39e-05
s.dist	0.523
p.adjustANOVA	0.000599

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	6956
DDX6	6873
DNA2	6809
ERCC3	6757
BLM	6598
CHD7	6521
HSPA5	6431
MCM9	6167
BRIP1	6145
FANCM	5646
MCM8	5563
DDX42	5426
DDX10	5253
PMS2	4265
MCM3	3675
DHX30	3263
MOV10	1740
DDX55	913
CHD1	55
DDX1	-715

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	6956
DDX6	6873
DNA2	6809
ERCC3	6757
BLM	6598
CHD7	6521
HSPA5	6431
MCM9	6167
BRIP1	6145
FANCM	5646
MCM8	5563
DDX42	5426
DDX10	5253
PMS2	4265
MCM3	3675
DHX30	3263
MOV10	1740
DDX55	913
CHD1	55
DDX1	-715
SUPV3L1	-1360
EIF4A3	-1787
EIF4A2	-4382

---

GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity

set	GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity
setSize	23
pANOVA	1.39e-05
s.dist	0.523
p.adjustANOVA	0.000599

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	6956
DDX6	6873
DNA2	6809
ERCC3	6757
BLM	6598
CHD7	6521
HSPA5	6431
MCM9	6167
BRIP1	6145
FANCM	5646
MCM8	5563
DDX42	5426
DDX10	5253
PMS2	4265
MCM3	3675
DHX30	3263
MOV10	1740
DDX55	913
CHD1	55
DDX1	-715

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	6956
DDX6	6873
DNA2	6809
ERCC3	6757
BLM	6598
CHD7	6521
HSPA5	6431
MCM9	6167
BRIP1	6145
FANCM	5646
MCM8	5563
DDX42	5426
DDX10	5253
PMS2	4265
MCM3	3675
DHX30	3263
MOV10	1740
DDX55	913
CHD1	55
DDX1	-715
SUPV3L1	-1360
EIF4A3	-1787
EIF4A2	-4382

---

GO:0140849 ATP-dependent H2AZ histone chaperone activity

set	GO:0140849 ATP-dependent H2AZ histone chaperone activity
setSize	23
pANOVA	1.39e-05
s.dist	0.523
p.adjustANOVA	0.000599

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	6956
DDX6	6873
DNA2	6809
ERCC3	6757
BLM	6598
CHD7	6521
HSPA5	6431
MCM9	6167
BRIP1	6145
FANCM	5646
MCM8	5563
DDX42	5426
DDX10	5253
PMS2	4265
MCM3	3675
DHX30	3263
MOV10	1740
DDX55	913
CHD1	55
DDX1	-715

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	6956
DDX6	6873
DNA2	6809
ERCC3	6757
BLM	6598
CHD7	6521
HSPA5	6431
MCM9	6167
BRIP1	6145
FANCM	5646
MCM8	5563
DDX42	5426
DDX10	5253
PMS2	4265
MCM3	3675
DHX30	3263
MOV10	1740
DDX55	913
CHD1	55
DDX1	-715
SUPV3L1	-1360
EIF4A3	-1787
EIF4A2	-4382

---

GO:0002218 activation of innate immune response

set	GO:0002218 activation of innate immune response
setSize	17
pANOVA	0.000242
s.dist	0.514
p.adjustANOVA	0.00639

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HSP90AA1	7179
SFPQ	6463
XRCC6	6403
NONO	6245
SIN3A	6018
XRCC5	5519
RBM14	4858
TBK1	4753
MATR3	3941
PRKDC	3830
CASP6	2752
IKBKE	2654
HEXIM1	2333
TOMM70	1971
PSPC1	1207
CGAS	-1362
TMEM173	-1697

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HSP90AA1	7179
SFPQ	6463
XRCC6	6403
NONO	6245
SIN3A	6018
XRCC5	5519
RBM14	4858
TBK1	4753
MATR3	3941
PRKDC	3830
CASP6	2752
IKBKE	2654
HEXIM1	2333
TOMM70	1971
PSPC1	1207
CGAS	-1362
TMEM173	-1697

---

GO:0001654 eye development

set	GO:0001654 eye development
setSize	17
pANOVA	0.000273
s.dist	-0.51
p.adjustANOVA	0.0069

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TGFBR3	-7123
TGFBR2	-6774
PXDN	-6683
ZDHHC16	-6336
CPAMD8	-5864
SMOC1	-5306
PBX3	-5189
BBS7	-4696
FREM2	-4670
TGFB2	-4633
MEIS2	-4408
SLC39A5	-3525
SCO2	-2799
RAB18	-2039
MEIS1	-1346
SH3PXD2B	4172
PBX4	5246

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TGFBR3	-7123
TGFBR2	-6774
PXDN	-6683
ZDHHC16	-6336
CPAMD8	-5864
SMOC1	-5306
PBX3	-5189
BBS7	-4696
FREM2	-4670
TGFB2	-4633
MEIS2	-4408
SLC39A5	-3525
SCO2	-2799
RAB18	-2039
MEIS1	-1346
SH3PXD2B	4172
PBX4	5246

---

GO:0140588 chromatin looping

set	GO:0140588 chromatin looping
setSize	27
pANOVA	4.53e-06
s.dist	0.51
p.adjustANOVA	0.000251

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BRD2	7161
TWNK	6956
DDX6	6873
DNA2	6809
ERCC3	6757
BLM	6598
PCBP2	6584
CHD7	6521
HSPA5	6431
MCM9	6167
BRIP1	6145
FANCM	5646
MCM8	5563
DDX42	5426
DDX10	5253
CTCF	4905
PMS2	4265
MCM3	3675
DHX30	3263
MOV10	1740

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BRD2	7161
TWNK	6956
DDX6	6873
DNA2	6809
ERCC3	6757
BLM	6598
PCBP2	6584
CHD7	6521
HSPA5	6431
MCM9	6167
BRIP1	6145
FANCM	5646
MCM8	5563
DDX42	5426
DDX10	5253
CTCF	4905
PMS2	4265
MCM3	3675
DHX30	3263
MOV10	1740
DDX55	913
CHD1	55
DDX1	-715
SUPV3L1	-1360
EIF4A3	-1787
EIF4A2	-4382
RAD21	-6225

---

GO:0005581 collagen trimer

set	GO:0005581 collagen trimer
setSize	21
pANOVA	8.02e-05
s.dist	-0.497
p.adjustANOVA	0.00259

Top enriched genes

Top 20 genes

GeneID	Gene Rank
C1QTNF3	-7170
COL6A1	-7137
COLEC12	-7075
COL6A2	-7048
COL18A1	-7047
COL3A1	-7043
COL8A1	-6929
COLEC10	-6699
COL6A3	-4994
COL12A1	-4830
COL8A2	-4761
COL9A2	-4210
LOX	-3881
COL14A1	-3729
COL10A1	-1398
COL21A1	-1209
EMID1	121
COL17A1	713
COL4A2	1747
COLEC11	2381

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
C1QTNF3	-7170
COL6A1	-7137
COLEC12	-7075
COL6A2	-7048
COL18A1	-7047
COL3A1	-7043
COL8A1	-6929
COLEC10	-6699
COL6A3	-4994
COL12A1	-4830
COL8A2	-4761
COL9A2	-4210
LOX	-3881
COL14A1	-3729
COL10A1	-1398
COL21A1	-1209
EMID1	121
COL17A1	713
COL4A2	1747
COLEC11	2381
COLQ	5593

---

GO:0007076 mitotic chromosome condensation

set	GO:0007076 mitotic chromosome condensation
setSize	10
pANOVA	0.00682
s.dist	0.494
p.adjustANOVA	0.0725

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NCAPH2	6912
SMC2	6908
AKAP8L	6305
NCAPD2	5655
NCAPH	5310
NUSAP1	4099
SMC4	3075
NCAPG	1403
NCAPD3	-367
PHF13	-3633

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NCAPH2	6912
SMC2	6908
AKAP8L	6305
NCAPD2	5655
NCAPH	5310
NUSAP1	4099
SMC4	3075
NCAPG	1403
NCAPD3	-367
PHF13	-3633

---

GO:0140658 ATP-dependent chromatin remodeler activity

set	GO:0140658 ATP-dependent chromatin remodeler activity
setSize	11
pANOVA	0.00456
s.dist	0.494
p.adjustANOVA	0.0535

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CHD4	6684
RAD54L2	6637
CHD7	6521
CHD2	6356
CHD1L	5273
CHD6	5074
CHD5	3455
ERCC6	1940
CHD1	55
INO80	-546
SMARCAD1	-2227

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CHD4	6684
RAD54L2	6637
CHD7	6521
CHD2	6356
CHD1L	5273
CHD6	5074
CHD5	3455
ERCC6	1940
CHD1	55
INO80	-546
SMARCAD1	-2227

---

GO:0070182 DNA polymerase binding

set	GO:0070182 DNA polymerase binding
setSize	13
pANOVA	0.00219
s.dist	0.491
p.adjustANOVA	0.0332

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HSP90AA1	7179
RTEL1	7013
FANCI	6878
NAT10	6801
SMG6	6542
SMARCA4	5990
LONP1	5462
FANCD2	4921
PCNA	4786
NABP2	1667
PTGES3	933
NHEJ1	-6015
POLG2	-6128

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HSP90AA1	7179
RTEL1	7013
FANCI	6878
NAT10	6801
SMG6	6542
SMARCA4	5990
LONP1	5462
FANCD2	4921
PCNA	4786
NABP2	1667
PTGES3	933
NHEJ1	-6015
POLG2	-6128

---

GO:0022626 cytosolic ribosome

set	GO:0022626 cytosolic ribosome
setSize	13
pANOVA	0.00222
s.dist	0.49
p.adjustANOVA	0.0333

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GCN1	6531
ETF1	6053
HBS1L	5564
USP10	4884
NEMF	4745
PELO	4311
RNF10	3906
METAP1	3388
LTN1	2636
RNF25	1604
GSPT2	1449
ASCC2	1252
RNF14	-346

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GCN1	6531
ETF1	6053
HBS1L	5564
USP10	4884
NEMF	4745
PELO	4311
RNF10	3906
METAP1	3388
LTN1	2636
RNF25	1604
GSPT2	1449
ASCC2	1252
RNF14	-346

---

GO:0045271 respiratory chain complex I

set	GO:0045271 respiratory chain complex I
setSize	31
pANOVA	2.71e-06
s.dist	-0.487
p.adjustANOVA	0.00016

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NDUFB3	-6886
NDUFB8	-6859
NDUFB9	-6657
NDUFB6	-6654
NDUFA2	-6644
NDUFAB1	-6492
NDUFV1	-6343
NDUFA13	-5839
NDUFB2	-5803
NDUFV3	-5795
NDUFS3	-5483
NDUFB5	-5421
NDUFA10	-5033
NDUFS8	-4877
NDUFB4	-4602
NDUFS4	-4284
ND5	-3913
NDUFA6	-3214
NDUFS2	-3142
NDUFS5	-2823

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NDUFB3	-6886
NDUFB8	-6859
NDUFB9	-6657
NDUFB6	-6654
NDUFA2	-6644
NDUFAB1	-6492
NDUFV1	-6343
NDUFA13	-5839
NDUFB2	-5803
NDUFV3	-5795
NDUFS3	-5483
NDUFB5	-5421
NDUFA10	-5033
NDUFS8	-4877
NDUFB4	-4602
NDUFS4	-4284
ND5	-3913
NDUFA6	-3214
NDUFS2	-3142
NDUFS5	-2823
NDUFA8	-1780
NDUFS6	-1763
NDUFV2	-1713
NDUFA5	-1575
NDUFA12	-1231
ND2	58
NDUFS7	198
NDUFA9	798
NDUFS1	1363
NDUFC2	1807
NDUFB10	2825

---

GO:0061462 protein localization to lysosome

set	GO:0061462 protein localization to lysosome
setSize	10
pANOVA	0.00785
s.dist	-0.485
p.adjustANOVA	0.0786

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CD81	-6705
KPTN	-6700
LAMTOR5	-6622
MFSD1	-5745
LMBRD1	-5428
SH3BP4	-5230
RTN4	-4530
KICS2	-498
RRAGC	2279
SZT2	4462

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CD81	-6705
KPTN	-6700
LAMTOR5	-6622
MFSD1	-5745
LMBRD1	-5428
SH3BP4	-5230
RTN4	-4530
KICS2	-498
RRAGC	2279
SZT2	4462

---

GO:0016442 RISC complex

set	GO:0016442 RISC complex
setSize	11
pANOVA	0.00539
s.dist	0.485
p.adjustANOVA	0.0616

Top enriched genes

Top 20 genes

GeneID	Gene Rank
XPO5	7041
DDX6	6873
LIMD1	5245
TNRC6A	4581
DCP2	4357
AGO2	3781
AGO3	3667
TARBP2	3529
EIF4E	3374
DICER1	448
AGO4	-4420

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
XPO5	7041
DDX6	6873
LIMD1	5245
TNRC6A	4581
DCP2	4357
AGO2	3781
AGO3	3667
TARBP2	3529
EIF4E	3374
DICER1	448
AGO4	-4420

---

GO:0003689 DNA clamp loader activity

set	GO:0003689 DNA clamp loader activity
setSize	32
pANOVA	2.17e-06
s.dist	0.484
p.adjustANOVA	0.000137

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	6956
DDX6	6873
DNA2	6809
ERCC3	6757
BLM	6598
DSCC1	6558
CHD7	6521
HSPA5	6431
MCM9	6167
BRIP1	6145
RFC3	5802
FANCM	5646
MCM8	5563
DDX42	5426
DDX10	5253
CHTF8	4853
RFC1	4638
PMS2	4265
CHTF18	3917
MCM3	3675

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	6956
DDX6	6873
DNA2	6809
ERCC3	6757
BLM	6598
DSCC1	6558
CHD7	6521
HSPA5	6431
MCM9	6167
BRIP1	6145
RFC3	5802
FANCM	5646
MCM8	5563
DDX42	5426
DDX10	5253
CHTF8	4853
RFC1	4638
PMS2	4265
CHTF18	3917
MCM3	3675
RFC2	3625
DHX30	3263
MOV10	1740
RFC4	1061
DDX55	913
CHD1	55
DDX1	-715
SUPV3L1	-1360
RAD17	-1638
EIF4A3	-1787
RFC5	-4021
EIF4A2	-4382

---

GO:0006406 mRNA export from nucleus

set	GO:0006406 mRNA export from nucleus
setSize	28
pANOVA	9.51e-06
s.dist	0.483
p.adjustANOVA	0.000468

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NUP155	6996
TPR	6976
NUP214	6964
NUP160	6838
XPO1	6602
NCBP1	6406
HNRNPA2B1	6364
NUP107	6299
SARNP	6224
THOC2	5901
SRSF3	5780
NUP133	5450
RBM15B	5326
THOC3	5001
MCM3AP	3696
EIF4E	3374
NUP85	2632
NCBP3	2199
THOC5	1364
FMR1	1137

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NUP155	6996
TPR	6976
NUP214	6964
NUP160	6838
XPO1	6602
NCBP1	6406
HNRNPA2B1	6364
NUP107	6299
SARNP	6224
THOC2	5901
SRSF3	5780
NUP133	5450
RBM15B	5326
THOC3	5001
MCM3AP	3696
EIF4E	3374
NUP85	2632
NCBP3	2199
THOC5	1364
FMR1	1137
FYTTD1	827
CHTOP	415
SHFM1	71
YTHDC1	-24
NUP88	-489
THOC1	-986
ENY2	-1100
THOC7	-2636

---

GO:1902774 late endosome to lysosome transport

set	GO:1902774 late endosome to lysosome transport
setSize	10
pANOVA	0.00817
s.dist	-0.483
p.adjustANOVA	0.0802

Top enriched genes

Top 20 genes

GeneID	Gene Rank
VPS39	-6258
C9orf72	-6042
CHMP2A	-5761
VPS41	-4450
CHMP5	-4169
CHMP2B	-3765
CHMP4C	-2204
CHMP1B	-1915
CHMP3	-700
CHMP7	724

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
VPS39	-6258
C9orf72	-6042
CHMP2A	-5761
VPS41	-4450
CHMP5	-4169
CHMP2B	-3765
CHMP4C	-2204
CHMP1B	-1915
CHMP3	-700
CHMP7	724

---

GO:0045116 protein neddylation

set	GO:0045116 protein neddylation
setSize	10
pANOVA	0.00835
s.dist	-0.482
p.adjustANOVA	0.0804

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RBX1	-6806
NEDD8	-5978
DCUN1D5	-5269
UBE2F	-5208
DCUN1D4	-4396
DCUN1D3	-4043
RNF7	-2728
UBA3	-2331
DCUN1D2	629
NAE1	1685

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RBX1	-6806
NEDD8	-5978
DCUN1D5	-5269
UBE2F	-5208
DCUN1D4	-4396
DCUN1D3	-4043
RNF7	-2728
UBA3	-2331
DCUN1D2	629
NAE1	1685

---

GO:0005518 collagen binding

set	GO:0005518 collagen binding
setSize	34
pANOVA	1.32e-06
s.dist	-0.479
p.adjustANOVA	8.98e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MRC2	-7167
COL6A1	-7137
CTSK	-7129
PODN	-7118
AEBP1	-7093
LUM	-7087
PDGFA	-7081
CTSB	-7014
CCBE1	-6961
P3H4	-6731
ANTXR1	-6452
ADGRG1	-6398
SPARC	-6383
TGFBI	-6356
SPOCK2	-5581
SERPINH1	-5557
LRRC15	-5408
CRTAP	-4653
SPOCK3	-4592
PCOLCE2	-4324

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MRC2	-7167
COL6A1	-7137
CTSK	-7129
PODN	-7118
AEBP1	-7093
LUM	-7087
PDGFA	-7081
CTSB	-7014
CCBE1	-6961
P3H4	-6731
ANTXR1	-6452
ADGRG1	-6398
SPARC	-6383
TGFBI	-6356
SPOCK2	-5581
SERPINH1	-5557
LRRC15	-5408
CRTAP	-4653
SPOCK3	-4592
PCOLCE2	-4324
LOX	-3881
ABI3BP	-3406
P3H1	-3382
PPIB	-2917
VWF	-2555
HSD17B12	-1711
SPARCL1	-42
ADAM9	436
NID1	1966
USH2A	2615
DDR2	5124
TMEM131	5224
CHADL	6083
PAK1	6322

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.4.2 (2024-10-31)
## Platform: x86_64-pc-linux-gnu
## Running under: Ubuntu 24.04.1 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.12.0 
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.12.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Australia/Melbourne
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] stats4    stats     graphics  grDevices utils     datasets  methods  
## [8] base     
## 
## other attached packages:
##  [1] pkgload_1.4.0               GGally_2.2.1               
##  [3] ggplot2_3.5.1               gtools_3.9.5               
##  [5] tibble_3.2.1                echarts4r_0.4.5            
##  [7] UpSetR_1.4.0                beeswarm_0.4.0             
##  [9] kableExtra_1.4.0            eulerr_7.0.2               
## [11] mitch_1.19.2                MASS_7.3-61                
## [13] gplots_3.2.0                DESeq2_1.44.0              
## [15] SummarizedExperiment_1.34.0 Biobase_2.64.0             
## [17] MatrixGenerics_1.16.0       matrixStats_1.4.1          
## [19] GenomicRanges_1.56.1        GenomeInfoDb_1.40.1        
## [21] IRanges_2.38.1              S4Vectors_0.42.1           
## [23] BiocGenerics_0.50.0         reshape2_1.4.4             
## [25] dplyr_1.1.4                 zoo_1.8-12                 
## 
## loaded via a namespace (and not attached):
##  [1] tidyselect_1.2.1        viridisLite_0.4.2       farver_2.1.2           
##  [4] bitops_1.0-9            fastmap_1.2.0           promises_1.3.2         
##  [7] digest_0.6.37           mime_0.12               lifecycle_1.0.4        
## [10] polylabelr_0.3.0        magrittr_2.0.3          compiler_4.4.2         
## [13] rlang_1.1.4             sass_0.4.9              tools_4.4.2            
## [16] yaml_2.3.10             knitr_1.49              labeling_0.4.3         
## [19] S4Arrays_1.4.1          htmlwidgets_1.6.4       DelayedArray_0.30.1    
## [22] xml2_1.3.6              plyr_1.8.9              RColorBrewer_1.1-3     
## [25] abind_1.4-8             BiocParallel_1.38.0     KernSmooth_2.23-24     
## [28] withr_3.0.2             purrr_1.0.2             polyclip_1.10-7        
## [31] grid_4.4.2              caTools_1.18.3          xtable_1.8-4           
## [34] colorspace_2.1-1        scales_1.3.0            cli_3.6.3              
## [37] rmarkdown_2.29          crayon_1.5.3            generics_0.1.3         
## [40] rstudioapi_0.17.1       httr_1.4.7              cachem_1.1.0           
## [43] stringr_1.5.1           zlibbioc_1.50.0         parallel_4.4.2         
## [46] XVector_0.44.0          vctrs_0.6.5             Matrix_1.7-1           
## [49] jsonlite_1.8.9          systemfonts_1.1.0       locfit_1.5-9.10        
## [52] jquerylib_0.1.4         tidyr_1.3.1             glue_1.8.0             
## [55] ggstats_0.7.0           codetools_0.2-20        stringi_1.8.4          
## [58] gtable_0.3.6            later_1.4.1             UCSC.utils_1.0.0       
## [61] munsell_0.5.1           pillar_1.10.0           htmltools_0.5.8.1      
## [64] GenomeInfoDbData_1.2.12 R6_2.5.1                evaluate_1.0.1         
## [67] shiny_1.10.0            lattice_0.22-6          httpuv_1.6.15          
## [70] bslib_0.8.0             Rcpp_1.0.13-1           svglite_2.1.3          
## [73] gridExtra_2.3           SparseArray_1.4.8       xfun_0.49              
## [76] pkgconfig_2.0.3

END of report