date generated: 2025-01-14

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch
stat
5_8S_rRNA 0.0572189
A4GALT -0.2750267
AAAS -0.4409637
AACS 0.3800663
AADAT 1.3142179
AAGAB -0.6075982

Here are some metrics about the input data profile:

Profiling data metrics
Profile metrics
num_genesets 5133
num_genes_in_profile 14327
duplicated_genes_present 0
num_profile_genes_in_sets 9152
num_profile_genes_not_in_sets 5175

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets:
Gene set metrics
Gene sets metrics
num_genesets 5133
num_genesets_excluded 3374
num_genesets_included 1759

Differential pathway expression


Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets
set setSize pANOVA s.dist p.adjustANOVA
GO:0042474 middle ear morphogenesis 10 8.82e-04 -0.607 8.51e-02
GO:0000245 spliceosomal complex assembly 10 2.10e-03 -0.562 1.23e-01
GO:0022625 cytosolic large ribosomal subunit 40 1.30e-09 -0.554 7.64e-07
GO:0022627 cytosolic small ribosomal subunit 25 1.01e-05 -0.510 2.53e-03
GO:0030016 myofibril 13 2.36e-03 0.487 1.30e-01
GO:1990391 DNA repair complex 10 8.23e-03 0.483 2.38e-01
GO:1990023 mitotic spindle midzone 10 8.35e-03 -0.482 2.38e-01
GO:0015813 L-glutamate transmembrane transport 11 6.06e-03 0.478 1.94e-01
GO:0001671 ATPase activator activity 18 4.73e-04 -0.476 6.70e-02
GO:0098761 cellular response to interleukin-7 10 9.59e-03 -0.473 2.43e-01
GO:0002181 cytoplasmic translation 27 2.15e-05 -0.472 4.72e-03
GO:0006730 one-carbon metabolic process 13 3.61e-03 0.466 1.48e-01
GO:0030155 regulation of cell adhesion 19 4.95e-04 0.462 6.70e-02
GO:0003333 amino acid transmembrane transport 10 1.24e-02 0.457 2.73e-01
GO:0035025 positive regulation of Rho protein signal transduction 10 1.26e-02 0.456 2.73e-01
GO:0001965 G-protein alpha-subunit binding 10 1.32e-02 0.453 2.73e-01
GO:0005762 mitochondrial large ribosomal subunit 38 1.45e-06 -0.452 6.04e-04
GO:0070412 R-SMAD binding 13 4.84e-03 -0.451 1.74e-01
GO:0045505 dynein intermediate chain binding 18 9.78e-04 0.449 8.51e-02
GO:0051382 kinetochore assembly 11 1.06e-02 -0.445 2.56e-01
GO:0003735 structural constituent of ribosome 118 1.96e-16 -0.438 3.46e-13
GO:0031032 actomyosin structure organization 17 1.86e-03 0.436 1.18e-01
GO:0006412 translation 96 4.49e-13 -0.428 3.95e-10
GO:0006623 protein targeting to vacuole 11 1.59e-02 0.420 2.92e-01
GO:0071007 U2-type catalytic step 2 spliceosome 24 3.84e-04 -0.419 6.70e-02
GO:0048278 vesicle docking 13 9.39e-03 -0.416 2.43e-01
GO:2000773 negative regulation of cellular senescence 12 1.31e-02 -0.414 2.73e-01
GO:0005828 kinetochore microtubule 10 2.38e-02 -0.413 3.46e-01
GO:0005201 extracellular matrix structural constituent 12 1.40e-02 0.410 2.80e-01
GO:0090443 FAR/SIN/STRIPAK complex 12 1.78e-02 -0.395 3.10e-01
GO:0045787 positive regulation of cell cycle 13 1.48e-02 -0.390 2.86e-01
GO:0061631 ubiquitin conjugating enzyme activity 24 9.54e-04 -0.390 8.51e-02
GO:0030946 protein tyrosine phosphatase activity, metal-dependent 15 9.04e-03 0.389 2.38e-01
GO:0140793 histone H2AXY142 phosphatase activity 15 9.04e-03 0.389 2.38e-01
GO:0036121 double-stranded DNA helicase activity 11 2.58e-02 0.388 3.59e-01
GO:0006744 ubiquinone biosynthetic process 11 2.70e-02 -0.385 3.59e-01
GO:0051959 dynein light intermediate chain binding 17 6.02e-03 0.385 1.94e-01
GO:0008139 nuclear localization sequence binding 13 1.65e-02 0.384 2.94e-01
GO:0048513 animal organ development 11 2.81e-02 -0.382 3.59e-01
GO:0043029 T cell homeostasis 13 1.84e-02 0.378 3.17e-01
GO:0051453 regulation of intracellular pH 14 1.52e-02 -0.375 2.86e-01
GO:0001782 B cell homeostasis 12 2.50e-02 0.374 3.54e-01
GO:0001657 ureteric bud development 14 1.61e-02 -0.371 2.93e-01
GO:0032526 response to retinoic acid 15 1.35e-02 -0.368 2.73e-01
GO:0048008 platelet-derived growth factor receptor signaling pathway 17 8.85e-03 0.367 2.38e-01
GO:0009925 basal plasma membrane 11 3.55e-02 0.366 3.81e-01
GO:0007076 mitotic chromosome condensation 10 4.51e-02 -0.366 4.31e-01
GO:0090201 negative regulation of release of cytochrome c from mitochondria 11 3.57e-02 -0.366 3.81e-01
GO:0050770 regulation of axonogenesis 13 2.27e-02 0.365 3.42e-01
GO:0035925 mRNA 3’-UTR AU-rich region binding 13 2.28e-02 -0.365 3.42e-01


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pANOVA s.dist p.adjustANOVA
GO:0042474 middle ear morphogenesis 10 8.82e-04 -6.07e-01 8.51e-02
GO:0000245 spliceosomal complex assembly 10 2.10e-03 -5.62e-01 1.23e-01
GO:0022625 cytosolic large ribosomal subunit 40 1.30e-09 -5.54e-01 7.64e-07
GO:0022627 cytosolic small ribosomal subunit 25 1.01e-05 -5.10e-01 2.53e-03
GO:0030016 myofibril 13 2.36e-03 4.87e-01 1.30e-01
GO:1990391 DNA repair complex 10 8.23e-03 4.83e-01 2.38e-01
GO:1990023 mitotic spindle midzone 10 8.35e-03 -4.82e-01 2.38e-01
GO:0015813 L-glutamate transmembrane transport 11 6.06e-03 4.78e-01 1.94e-01
GO:0001671 ATPase activator activity 18 4.73e-04 -4.76e-01 6.70e-02
GO:0098761 cellular response to interleukin-7 10 9.59e-03 -4.73e-01 2.43e-01
GO:0002181 cytoplasmic translation 27 2.15e-05 -4.72e-01 4.72e-03
GO:0006730 one-carbon metabolic process 13 3.61e-03 4.66e-01 1.48e-01
GO:0030155 regulation of cell adhesion 19 4.95e-04 4.62e-01 6.70e-02
GO:0003333 amino acid transmembrane transport 10 1.24e-02 4.57e-01 2.73e-01
GO:0035025 positive regulation of Rho protein signal transduction 10 1.26e-02 4.56e-01 2.73e-01
GO:0001965 G-protein alpha-subunit binding 10 1.32e-02 4.53e-01 2.73e-01
GO:0005762 mitochondrial large ribosomal subunit 38 1.45e-06 -4.52e-01 6.04e-04
GO:0070412 R-SMAD binding 13 4.84e-03 -4.51e-01 1.74e-01
GO:0045505 dynein intermediate chain binding 18 9.78e-04 4.49e-01 8.51e-02
GO:0051382 kinetochore assembly 11 1.06e-02 -4.45e-01 2.56e-01
GO:0003735 structural constituent of ribosome 118 1.96e-16 -4.38e-01 3.46e-13
GO:0031032 actomyosin structure organization 17 1.86e-03 4.36e-01 1.18e-01
GO:0006412 translation 96 4.49e-13 -4.28e-01 3.95e-10
GO:0006623 protein targeting to vacuole 11 1.59e-02 4.20e-01 2.92e-01
GO:0071007 U2-type catalytic step 2 spliceosome 24 3.84e-04 -4.19e-01 6.70e-02
GO:0048278 vesicle docking 13 9.39e-03 -4.16e-01 2.43e-01
GO:2000773 negative regulation of cellular senescence 12 1.31e-02 -4.14e-01 2.73e-01
GO:0005828 kinetochore microtubule 10 2.38e-02 -4.13e-01 3.46e-01
GO:0005201 extracellular matrix structural constituent 12 1.40e-02 4.10e-01 2.80e-01
GO:0090443 FAR/SIN/STRIPAK complex 12 1.78e-02 -3.95e-01 3.10e-01
GO:0045787 positive regulation of cell cycle 13 1.48e-02 -3.90e-01 2.86e-01
GO:0061631 ubiquitin conjugating enzyme activity 24 9.54e-04 -3.90e-01 8.51e-02
GO:0030946 protein tyrosine phosphatase activity, metal-dependent 15 9.04e-03 3.89e-01 2.38e-01
GO:0140793 histone H2AXY142 phosphatase activity 15 9.04e-03 3.89e-01 2.38e-01
GO:0036121 double-stranded DNA helicase activity 11 2.58e-02 3.88e-01 3.59e-01
GO:0006744 ubiquinone biosynthetic process 11 2.70e-02 -3.85e-01 3.59e-01
GO:0051959 dynein light intermediate chain binding 17 6.02e-03 3.85e-01 1.94e-01
GO:0008139 nuclear localization sequence binding 13 1.65e-02 3.84e-01 2.94e-01
GO:0048513 animal organ development 11 2.81e-02 -3.82e-01 3.59e-01
GO:0043029 T cell homeostasis 13 1.84e-02 3.78e-01 3.17e-01
GO:0051453 regulation of intracellular pH 14 1.52e-02 -3.75e-01 2.86e-01
GO:0001782 B cell homeostasis 12 2.50e-02 3.74e-01 3.54e-01
GO:0001657 ureteric bud development 14 1.61e-02 -3.71e-01 2.93e-01
GO:0032526 response to retinoic acid 15 1.35e-02 -3.68e-01 2.73e-01
GO:0048008 platelet-derived growth factor receptor signaling pathway 17 8.85e-03 3.67e-01 2.38e-01
GO:0009925 basal plasma membrane 11 3.55e-02 3.66e-01 3.81e-01
GO:0007076 mitotic chromosome condensation 10 4.51e-02 -3.66e-01 4.31e-01
GO:0090201 negative regulation of release of cytochrome c from mitochondria 11 3.57e-02 -3.66e-01 3.81e-01
GO:0050770 regulation of axonogenesis 13 2.27e-02 3.65e-01 3.42e-01
GO:0035925 mRNA 3’-UTR AU-rich region binding 13 2.28e-02 -3.65e-01 3.42e-01
GO:0048144 fibroblast proliferation 22 3.22e-03 -3.63e-01 1.42e-01
GO:0000124 SAGA complex 15 1.52e-02 -3.62e-01 2.86e-01
GO:0005125 cytokine activity 28 1.02e-03 -3.59e-01 8.51e-02
GO:0042073 intraciliary transport 16 1.31e-02 -3.58e-01 2.73e-01
GO:0008542 visual learning 20 5.61e-03 3.58e-01 1.90e-01
GO:0048666 neuron development 26 1.65e-03 -3.57e-01 1.11e-01
GO:0032012 regulation of ARF protein signal transduction 14 2.11e-02 3.56e-01 3.37e-01
GO:0043923 positive regulation by host of viral transcription 12 3.56e-02 -3.50e-01 3.81e-01
GO:0006695 cholesterol biosynthetic process 16 1.53e-02 -3.50e-01 2.86e-01
GO:0009378 four-way junction helicase activity 13 2.93e-02 3.49e-01 3.59e-01
GO:0005158 insulin receptor binding 13 2.96e-02 3.48e-01 3.59e-01
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT 11 4.57e-02 -3.48e-01 4.32e-01
GO:0048863 stem cell differentiation 21 6.24e-03 -3.45e-01 1.96e-01
GO:0045595 regulation of cell differentiation 13 3.15e-02 -3.45e-01 3.67e-01
GO:0140672 ATAC complex 11 4.95e-02 -3.42e-01 4.46e-01
GO:0009954 proximal/distal pattern formation 14 2.73e-02 -3.41e-01 3.59e-01
GO:0009968 negative regulation of signal transduction 14 2.74e-02 3.40e-01 3.59e-01
GO:0035115 embryonic forelimb morphogenesis 16 1.97e-02 -3.37e-01 3.23e-01
GO:0016514 SWI/SNF complex 20 9.67e-03 3.34e-01 2.43e-01
GO:0141198 protein branched polyubiquitination 13 3.82e-02 3.32e-01 3.98e-01
GO:0006622 protein targeting to lysosome 15 2.62e-02 3.32e-01 3.59e-01
GO:2000378 negative regulation of reactive oxygen species metabolic process 10 7.20e-02 3.29e-01 5.56e-01
GO:0051290 protein heterotetramerization 10 7.28e-02 3.28e-01 5.56e-01
GO:0097038 perinuclear endoplasmic reticulum 10 7.29e-02 -3.28e-01 5.56e-01
GO:0034097 response to cytokine 12 5.06e-02 3.26e-01 4.48e-01
GO:0030150 protein import into mitochondrial matrix 12 5.07e-02 -3.26e-01 4.48e-01
GO:0042100 B cell proliferation 14 3.48e-02 -3.26e-01 3.81e-01
GO:0046966 nuclear thyroid hormone receptor binding 15 2.96e-02 3.24e-01 3.59e-01
GO:0016282 eukaryotic 43S preinitiation complex 14 3.57e-02 -3.24e-01 3.81e-01
GO:0006310 DNA recombination 23 7.22e-03 -3.24e-01 2.15e-01
GO:0045271 respiratory chain complex I 31 2.00e-03 -3.21e-01 1.21e-01
GO:0005852 eukaryotic translation initiation factor 3 complex 10 7.90e-02 -3.21e-01 5.72e-01
GO:0071816 tail-anchored membrane protein insertion into ER membrane 10 8.24e-02 -3.17e-01 5.86e-01
GO:0050850 positive regulation of calcium-mediated signaling 10 8.40e-02 -3.16e-01 5.86e-01
GO:0001819 positive regulation of cytokine production 13 4.99e-02 -3.14e-01 4.48e-01
GO:0000407 phagophore assembly site 20 1.56e-02 -3.12e-01 2.89e-01
GO:0140359 ABC-type transporter activity 10 8.73e-02 3.12e-01 5.92e-01
GO:0012506 vesicle membrane 16 3.07e-02 -3.12e-01 3.62e-01
GO:0080008 Cul4-RING E3 ubiquitin ligase complex 13 5.15e-02 -3.12e-01 4.53e-01
GO:0005840 ribosome 43 4.36e-04 -3.10e-01 6.70e-02
GO:0043138 3’-5’ DNA helicase activity 10 9.04e-02 3.09e-01 5.95e-01
GO:0051233 spindle midzone 17 2.74e-02 -3.09e-01 3.59e-01
GO:0030901 midbrain development 11 7.63e-02 -3.09e-01 5.62e-01
GO:0009791 post-embryonic development 36 1.40e-03 3.08e-01 1.03e-01
GO:0071560 cellular response to transforming growth factor beta stimulus 16 3.32e-02 -3.07e-01 3.80e-01
GO:0016442 RISC complex 11 7.81e-02 3.07e-01 5.69e-01
GO:0019933 cAMP-mediated signaling 13 5.71e-02 -3.05e-01 4.87e-01
GO:0007528 neuromuscular junction development 15 4.18e-02 3.04e-01 4.27e-01
GO:0009887 animal organ morphogenesis 34 2.22e-03 3.03e-01 1.26e-01
GO:0000974 Prp19 complex 10 9.86e-02 -3.02e-01 5.95e-01
GO:0000086 G2/M transition of mitotic cell cycle 25 9.06e-03 -3.02e-01 2.38e-01
GO:0050829 defense response to Gram-negative bacterium 12 7.19e-02 -3.00e-01 5.56e-01
GO:0004402 histone acetyltransferase activity 11 8.49e-02 3.00e-01 5.86e-01
GO:0051209 release of sequestered calcium ion into cytosol 19 2.38e-02 3.00e-01 3.46e-01
GO:0043122 regulation of canonical NF-kappaB signal transduction 18 2.80e-02 -2.99e-01 3.59e-01
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 11 8.60e-02 -2.99e-01 5.91e-01
GO:0001938 positive regulation of endothelial cell proliferation 23 1.35e-02 -2.98e-01 2.73e-01
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 19 2.48e-02 2.98e-01 3.54e-01
GO:0060038 cardiac muscle cell proliferation 12 7.48e-02 -2.97e-01 5.60e-01
GO:0042733 embryonic digit morphogenesis 30 4.91e-03 -2.97e-01 1.74e-01
GO:0060828 regulation of canonical Wnt signaling pathway 18 2.93e-02 2.97e-01 3.59e-01
GO:0140311 protein sequestering activity 18 2.95e-02 -2.96e-01 3.59e-01
GO:0032981 mitochondrial respiratory chain complex I assembly 38 1.61e-03 -2.96e-01 1.11e-01
GO:0071526 semaphorin-plexin signaling pathway 21 1.90e-02 2.96e-01 3.19e-01
GO:0032039 integrator complex 15 4.75e-02 -2.96e-01 4.35e-01
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 11 9.13e-02 -2.94e-01 5.95e-01
GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 15 4.90e-02 -2.94e-01 4.44e-01
GO:0048706 embryonic skeletal system development 16 4.21e-02 -2.93e-01 4.28e-01
GO:0071233 cellular response to L-leucine 10 1.08e-01 2.93e-01 5.96e-01
GO:0031398 positive regulation of protein ubiquitination 40 1.41e-03 -2.92e-01 1.03e-01
GO:0031167 rRNA methylation 11 9.49e-02 -2.91e-01 5.95e-01
GO:0055013 cardiac muscle cell development 11 9.52e-02 2.91e-01 5.95e-01
GO:0099171 presynaptic modulation of chemical synaptic transmission 11 9.59e-02 -2.90e-01 5.95e-01
GO:0001707 mesoderm formation 15 5.20e-02 2.90e-01 4.55e-01
GO:0044297 cell body 22 1.93e-02 -2.88e-01 3.21e-01
GO:1902018 negative regulation of cilium assembly 13 7.44e-02 2.86e-01 5.59e-01
GO:0030168 platelet activation 11 1.01e-01 2.85e-01 5.96e-01
GO:2000648 positive regulation of stem cell proliferation 12 8.74e-02 -2.85e-01 5.92e-01
GO:0002040 sprouting angiogenesis 18 3.65e-02 2.85e-01 3.84e-01
GO:0016529 sarcoplasmic reticulum 13 7.58e-02 2.84e-01 5.62e-01
GO:0004386 helicase activity 40 1.88e-03 2.84e-01 1.18e-01
GO:0033344 cholesterol efflux 11 1.05e-01 2.82e-01 5.96e-01
GO:0016925 protein sumoylation 19 3.35e-02 -2.82e-01 3.80e-01
GO:1902894 negative regulation of miRNA transcription 12 9.18e-02 2.81e-01 5.95e-01
GO:0071333 cellular response to glucose stimulus 12 9.20e-02 2.81e-01 5.95e-01
GO:0048786 presynaptic active zone 11 1.09e-01 2.79e-01 5.96e-01
GO:0016601 Rac protein signal transduction 17 4.65e-02 2.79e-01 4.33e-01
GO:0033209 tumor necrosis factor-mediated signaling pathway 15 6.15e-02 2.79e-01 5.03e-01
GO:0005882 intermediate filament 19 3.55e-02 2.79e-01 3.81e-01
GO:0035098 ESC/E(Z) complex 12 9.69e-02 -2.77e-01 5.95e-01
GO:0014032 neural crest cell development 11 1.12e-01 2.77e-01 6.06e-01
GO:0007080 mitotic metaphase chromosome alignment 23 2.16e-02 -2.77e-01 3.40e-01
GO:0005164 tumor necrosis factor receptor binding 13 8.44e-02 -2.76e-01 5.86e-01
GO:0000939 inner kinetochore 10 1.30e-01 -2.76e-01 6.41e-01
GO:0043408 regulation of MAPK cascade 21 2.84e-02 2.76e-01 3.59e-01
GO:0008306 associative learning 11 1.13e-01 2.76e-01 6.06e-01
GO:0005666 RNA polymerase III complex 12 9.88e-02 -2.75e-01 5.95e-01
GO:0006898 receptor-mediated endocytosis 23 2.29e-02 2.74e-01 3.42e-01
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 38 3.47e-03 2.74e-01 1.48e-01
GO:0030330 DNA damage response, signal transduction by p53 class mediator 12 1.00e-01 2.74e-01 5.95e-01
GO:0001568 blood vessel development 19 4.00e-02 2.72e-01 4.14e-01
GO:0030970 retrograde protein transport, ER to cytosol 12 1.03e-01 -2.72e-01 5.96e-01
GO:0030992 intraciliary transport particle B 15 6.84e-02 -2.72e-01 5.42e-01
GO:0043425 bHLH transcription factor binding 10 1.38e-01 2.71e-01 6.55e-01
GO:0005689 U12-type spliceosomal complex 20 3.62e-02 -2.71e-01 3.83e-01
GO:0030225 macrophage differentiation 11 1.20e-01 -2.70e-01 6.13e-01
GO:0032543 mitochondrial translation 22 2.84e-02 -2.70e-01 3.59e-01
GO:0001530 lipopolysaccharide binding 12 1.06e-01 -2.70e-01 5.96e-01
GO:0046540 U4/U6 x U5 tri-snRNP complex 23 2.53e-02 -2.69e-01 3.57e-01
GO:0031669 cellular response to nutrient levels 13 9.29e-02 2.69e-01 5.95e-01
GO:0051019 mitogen-activated protein kinase binding 11 1.23e-01 -2.69e-01 6.19e-01
GO:0035791 platelet-derived growth factor receptor-beta signaling pathway 15 7.17e-02 2.69e-01 5.56e-01
GO:0030220 platelet formation 11 1.26e-01 2.66e-01 6.30e-01
GO:0034605 cellular response to heat 16 6.62e-02 -2.65e-01 5.35e-01
GO:0016180 snRNA processing 10 1.47e-01 -2.65e-01 6.62e-01
GO:0051315 attachment of mitotic spindle microtubules to kinetochore 10 1.47e-01 -2.65e-01 6.62e-01
GO:0060395 SMAD protein signal transduction 14 8.89e-02 2.63e-01 5.95e-01
GO:0070371 ERK1 and ERK2 cascade 19 4.84e-02 -2.62e-01 4.42e-01
GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 13 1.03e-01 2.61e-01 5.96e-01
GO:0072542 protein phosphatase activator activity 10 1.52e-01 2.61e-01 6.62e-01
GO:0005006 epidermal growth factor receptor activity 14 9.05e-02 2.61e-01 5.95e-01
GO:0140326 ATPase-coupled intramembrane lipid transporter activity 11 1.34e-01 2.61e-01 6.47e-01
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 15 8.07e-02 2.61e-01 5.82e-01
GO:0000176 nuclear exosome (RNase complex) 12 1.18e-01 -2.60e-01 6.11e-01
GO:0005685 U1 snRNP 12 1.19e-01 -2.60e-01 6.11e-01
GO:0045785 positive regulation of cell adhesion 15 8.13e-02 2.60e-01 5.84e-01
GO:0050796 regulation of insulin secretion 12 1.20e-01 -2.59e-01 6.13e-01
GO:0050767 regulation of neurogenesis 14 9.44e-02 -2.58e-01 5.95e-01
GO:0005778 peroxisomal membrane 28 1.86e-02 2.57e-01 3.17e-01
GO:0061749 forked DNA-dependent helicase activity 10 1.61e-01 2.56e-01 6.62e-01
GO:0048675 axon extension 14 9.93e-02 2.54e-01 5.95e-01
GO:0032924 activin receptor signaling pathway 12 1.27e-01 2.54e-01 6.34e-01
GO:0048147 negative regulation of fibroblast proliferation 14 9.96e-02 2.54e-01 5.95e-01
GO:0050905 neuromuscular process 10 1.64e-01 2.54e-01 6.67e-01
GO:0007059 chromosome segregation 41 4.95e-03 -2.54e-01 1.74e-01
GO:0038066 p38MAPK cascade 11 1.46e-01 -2.53e-01 6.62e-01
GO:0006884 cell volume homeostasis 14 1.03e-01 2.52e-01 5.96e-01
GO:0007052 mitotic spindle organization 34 1.11e-02 -2.52e-01 2.59e-01
GO:0050885 neuromuscular process controlling balance 23 3.67e-02 2.52e-01 3.84e-01
GO:0000387 spliceosomal snRNP assembly 17 7.30e-02 -2.51e-01 5.56e-01
GO:0005544 calcium-dependent phospholipid binding 21 4.63e-02 -2.51e-01 4.33e-01
GO:0043627 response to estrogen 10 1.70e-01 -2.51e-01 6.73e-01
GO:0035613 RNA stem-loop binding 11 1.51e-01 2.50e-01 6.62e-01
GO:0033290 eukaryotic 48S preinitiation complex 13 1.18e-01 -2.50e-01 6.11e-01
GO:0002020 protease binding 44 4.16e-03 2.50e-01 1.63e-01
GO:0035278 miRNA-mediated gene silencing by inhibition of translation 12 1.34e-01 2.50e-01 6.47e-01
GO:0034446 substrate adhesion-dependent cell spreading 33 1.33e-02 2.49e-01 2.73e-01
GO:0046034 ATP metabolic process 13 1.21e-01 2.49e-01 6.13e-01
GO:0042593 glucose homeostasis 42 5.41e-03 -2.48e-01 1.86e-01
GO:0048568 embryonic organ development 15 9.75e-02 -2.47e-01 5.95e-01
GO:0007094 mitotic spindle assembly checkpoint signaling 19 6.27e-02 -2.47e-01 5.10e-01
GO:0019905 syntaxin binding 25 3.28e-02 -2.47e-01 3.79e-01
GO:0043531 ADP binding 20 5.62e-02 2.47e-01 4.83e-01
GO:0019003 GDP binding 44 4.72e-03 -2.46e-01 1.74e-01
GO:0034497 protein localization to phagophore assembly site 11 1.59e-01 -2.45e-01 6.62e-01
GO:0051056 regulation of small GTPase mediated signal transduction 16 8.97e-02 2.45e-01 5.95e-01
GO:0098656 monoatomic anion transmembrane transport 18 7.26e-02 -2.44e-01 5.56e-01
GO:0008361 regulation of cell size 13 1.29e-01 2.43e-01 6.39e-01
GO:0003755 peptidyl-prolyl cis-trans isomerase activity 30 2.10e-02 -2.43e-01 3.37e-01
GO:0140658 ATP-dependent chromatin remodeler activity 11 1.62e-01 2.43e-01 6.64e-01
GO:0022008 neurogenesis 31 1.90e-02 2.43e-01 3.19e-01
GO:0140861 DNA repair-dependent chromatin remodeling 14 1.15e-01 2.43e-01 6.08e-01
GO:0006749 glutathione metabolic process 15 1.04e-01 -2.43e-01 5.96e-01
GO:0016342 catenin complex 13 1.30e-01 2.42e-01 6.41e-01
GO:0002931 response to ischemia 10 1.88e-01 -2.41e-01 6.90e-01
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 19 6.97e-02 2.40e-01 5.50e-01
GO:0045879 negative regulation of smoothened signaling pathway 15 1.09e-01 -2.39e-01 5.96e-01
GO:0033173 calcineurin-NFAT signaling cascade 10 1.93e-01 2.38e-01 6.92e-01
GO:1990498 mitotic spindle microtubule 10 1.93e-01 -2.38e-01 6.92e-01
GO:0008217 regulation of blood pressure 19 7.34e-02 2.37e-01 5.57e-01
GO:0007274 neuromuscular synaptic transmission 12 1.55e-01 2.37e-01 6.62e-01
GO:0006644 phospholipid metabolic process 11 1.74e-01 2.37e-01 6.81e-01
GO:0030900 forebrain development 20 6.69e-02 2.37e-01 5.35e-01
GO:0019843 rRNA binding 22 5.56e-02 -2.36e-01 4.81e-01
GO:0042026 protein refolding 12 1.58e-01 -2.36e-01 6.62e-01
GO:0016226 iron-sulfur cluster assembly 17 9.29e-02 -2.35e-01 5.95e-01
GO:0035269 protein O-linked mannosylation 13 1.42e-01 2.35e-01 6.62e-01
GO:0045648 positive regulation of erythrocyte differentiation 18 8.48e-02 2.35e-01 5.86e-01
GO:0045171 intercellular bridge 55 2.62e-03 -2.35e-01 1.35e-01
GO:0030282 bone mineralization 22 5.74e-02 2.34e-01 4.87e-01
GO:0042626 ATPase-coupled transmembrane transporter activity 16 1.05e-01 2.34e-01 5.96e-01
GO:0045332 phospholipid translocation 15 1.17e-01 2.34e-01 6.08e-01
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 31 2.44e-02 2.34e-01 3.52e-01
GO:0050714 positive regulation of protein secretion 19 7.83e-02 -2.33e-01 5.69e-01
GO:0034332 adherens junction organization 11 1.81e-01 2.33e-01 6.89e-01
GO:0030217 T cell differentiation 18 8.71e-02 2.33e-01 5.92e-01
GO:0044344 cellular response to fibroblast growth factor stimulus 10 2.03e-01 -2.33e-01 6.96e-01
GO:0001508 action potential 11 1.82e-01 2.32e-01 6.90e-01
GO:0005019 platelet-derived growth factor beta-receptor activity 13 1.48e-01 2.32e-01 6.62e-01
GO:0072344 rescue of stalled ribosome 26 4.11e-02 -2.31e-01 4.23e-01
GO:0042102 positive regulation of T cell proliferation 10 2.05e-01 2.31e-01 6.96e-01
GO:0140416 transcription regulator inhibitor activity 12 1.65e-01 -2.31e-01 6.67e-01
GO:0004497 monooxygenase activity 11 1.86e-01 2.30e-01 6.90e-01
GO:0070628 proteasome binding 13 1.51e-01 2.30e-01 6.62e-01
GO:0051082 unfolded protein binding 56 2.93e-03 -2.30e-01 1.36e-01
GO:0030897 HOPS complex 10 2.08e-01 2.30e-01 6.96e-01
GO:0002088 lens development in camera-type eye 13 1.51e-01 2.30e-01 6.62e-01
GO:0007339 binding of sperm to zona pellucida 11 1.88e-01 -2.29e-01 6.90e-01
GO:0005604 basement membrane 42 1.04e-02 2.28e-01 2.56e-01
GO:0001569 branching involved in blood vessel morphogenesis 15 1.26e-01 2.28e-01 6.30e-01
GO:0002682 regulation of immune system process 11 1.90e-01 2.28e-01 6.91e-01
GO:0009615 response to virus 29 3.38e-02 -2.28e-01 3.80e-01
GO:0046488 phosphatidylinositol metabolic process 13 1.55e-01 2.28e-01 6.62e-01
GO:0030544 Hsp70 protein binding 29 3.41e-02 -2.27e-01 3.80e-01
GO:0005782 peroxisomal matrix 10 2.14e-01 2.27e-01 6.96e-01
GO:0050870 positive regulation of T cell activation 14 1.43e-01 -2.26e-01 6.62e-01
GO:0005010 insulin-like growth factor receptor activity 13 1.59e-01 2.26e-01 6.62e-01
GO:0009888 tissue development 18 9.74e-02 2.26e-01 5.95e-01
GO:0034063 stress granule assembly 21 7.41e-02 2.25e-01 5.59e-01
GO:0030030 cell projection organization 13 1.63e-01 -2.24e-01 6.64e-01
GO:0050918 positive chemotaxis 13 1.64e-01 -2.23e-01 6.67e-01
GO:0007155 cell adhesion 104 9.52e-05 2.22e-01 1.86e-02
GO:0005665 RNA polymerase II, core complex 10 2.25e-01 -2.22e-01 7.08e-01
GO:0003180 aortic valve morphogenesis 11 2.03e-01 2.22e-01 6.96e-01
GO:0003824 catalytic activity 10 2.27e-01 -2.21e-01 7.12e-01
GO:0006303 double-strand break repair via nonhomologous end joining 20 8.78e-02 2.21e-01 5.92e-01
GO:0051536 iron-sulfur cluster binding 12 1.86e-01 -2.21e-01 6.90e-01
GO:0005801 cis-Golgi network 28 4.45e-02 2.19e-01 4.31e-01
GO:0008289 lipid binding 45 1.12e-02 -2.19e-01 2.59e-01
GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels 16 1.31e-01 2.18e-01 6.41e-01
GO:0006816 calcium ion transport 19 1.00e-01 -2.18e-01 5.95e-01
GO:0061952 midbody abscission 14 1.59e-01 -2.17e-01 6.62e-01
GO:1905564 positive regulation of vascular endothelial cell proliferation 10 2.35e-01 -2.17e-01 7.13e-01
GO:0003007 heart morphogenesis 16 1.34e-01 2.16e-01 6.47e-01
GO:0035914 skeletal muscle cell differentiation 24 6.69e-02 2.16e-01 5.35e-01
GO:0015908 fatty acid transport 11 2.15e-01 -2.16e-01 6.96e-01
GO:0048704 embryonic skeletal system morphogenesis 18 1.13e-01 -2.16e-01 6.06e-01
GO:0006672 ceramide metabolic process 10 2.38e-01 2.15e-01 7.13e-01
GO:0004721 phosphoprotein phosphatase activity 21 8.75e-02 2.15e-01 5.92e-01
GO:0046513 ceramide biosynthetic process 19 1.04e-01 -2.15e-01 5.96e-01
GO:0000422 autophagy of mitochondrion 14 1.65e-01 -2.14e-01 6.67e-01
GO:0006337 nucleosome disassembly 10 2.41e-01 2.14e-01 7.16e-01
GO:0001725 stress fiber 42 1.65e-02 2.14e-01 2.94e-01
GO:0031526 brush border membrane 12 2.00e-01 2.13e-01 6.96e-01
GO:0016197 endosomal transport 27 5.49e-02 2.13e-01 4.78e-01
GO:0031547 brain-derived neurotrophic factor receptor signaling pathway 14 1.69e-01 2.12e-01 6.73e-01
GO:0034976 response to endoplasmic reticulum stress 33 3.56e-02 -2.11e-01 3.81e-01
GO:0000776 kinetochore 90 5.38e-04 -2.11e-01 6.76e-02
GO:0006120 mitochondrial electron transport, NADH to ubiquinone 19 1.12e-01 -2.11e-01 6.06e-01
GO:0006284 base-excision repair 17 1.34e-01 -2.10e-01 6.47e-01
GO:0009749 response to glucose 14 1.74e-01 2.10e-01 6.81e-01
GO:0005009 insulin receptor activity 14 1.74e-01 2.10e-01 6.81e-01
GO:0033617 mitochondrial cytochrome c oxidase assembly 13 1.90e-01 -2.10e-01 6.91e-01
GO:0030336 negative regulation of cell migration 50 1.05e-02 2.09e-01 2.56e-01
GO:0043124 negative regulation of canonical NF-kappaB signal transduction 36 3.00e-02 -2.09e-01 3.59e-01
GO:0001974 blood vessel remodeling 17 1.36e-01 2.09e-01 6.50e-01
GO:0071011 precatalytic spliceosome 12 2.10e-01 -2.09e-01 6.96e-01
GO:0000228 nuclear chromosome 13 1.93e-01 -2.09e-01 6.92e-01
GO:0008013 beta-catenin binding 46 1.45e-02 2.09e-01 2.86e-01
GO:0007064 mitotic sister chromatid cohesion 10 2.54e-01 -2.08e-01 7.28e-01
GO:0042056 chemoattractant activity 11 2.33e-01 -2.08e-01 7.13e-01
GO:0090303 positive regulation of wound healing 11 2.33e-01 -2.08e-01 7.13e-01
GO:0001732 formation of cytoplasmic translation initiation complex 12 2.13e-01 -2.08e-01 6.96e-01
GO:2000045 regulation of G1/S transition of mitotic cell cycle 19 1.17e-01 -2.08e-01 6.08e-01
GO:0010575 positive regulation of vascular endothelial growth factor production 13 1.96e-01 2.07e-01 6.94e-01
GO:0003341 cilium movement 10 2.57e-01 2.07e-01 7.31e-01
GO:0030490 maturation of SSU-rRNA 12 2.15e-01 -2.07e-01 6.96e-01
GO:0031252 cell leading edge 18 1.29e-01 2.07e-01 6.40e-01
GO:1902774 late endosome to lysosome transport 10 2.59e-01 -2.06e-01 7.31e-01
GO:0022626 cytosolic ribosome 13 1.98e-01 2.06e-01 6.96e-01
GO:0001678 intracellular glucose homeostasis 17 1.43e-01 2.05e-01 6.62e-01
GO:0005021 vascular endothelial growth factor receptor activity 15 1.69e-01 2.05e-01 6.73e-01
GO:0045116 protein neddylation 10 2.62e-01 -2.05e-01 7.31e-01
GO:0009898 cytoplasmic side of plasma membrane 47 1.53e-02 -2.05e-01 2.86e-01
GO:0008333 endosome to lysosome transport 32 4.54e-02 2.04e-01 4.32e-01
GO:0004521 RNA endonuclease activity 20 1.14e-01 -2.04e-01 6.07e-01
GO:0005154 epidermal growth factor receptor binding 19 1.24e-01 2.04e-01 6.21e-01
GO:0051721 protein phosphatase 2A binding 14 1.86e-01 2.04e-01 6.90e-01
GO:0060325 face morphogenesis 20 1.15e-01 2.04e-01 6.08e-01
GO:0034450 ubiquitin-ubiquitin ligase activity 12 2.22e-01 2.04e-01 7.03e-01
GO:0031468 nuclear membrane reassembly 11 2.43e-01 -2.03e-01 7.19e-01
GO:0030073 insulin secretion 14 1.88e-01 -2.03e-01 6.90e-01
GO:0071013 catalytic step 2 spliceosome 52 1.13e-02 -2.03e-01 2.59e-01
GO:0005912 adherens junction 69 3.59e-03 2.03e-01 1.48e-01
GO:0030286 dynein complex 11 2.44e-01 2.03e-01 7.20e-01
GO:0015459 potassium channel regulator activity 12 2.24e-01 2.03e-01 7.06e-01
GO:0001658 branching involved in ureteric bud morphogenesis 17 1.48e-01 2.02e-01 6.62e-01
GO:2001235 positive regulation of apoptotic signaling pathway 17 1.49e-01 -2.02e-01 6.62e-01
GO:0034704 calcium channel complex 10 2.69e-01 -2.02e-01 7.32e-01
GO:0045444 fat cell differentiation 44 2.06e-02 -2.02e-01 3.36e-01
GO:0070577 lysine-acetylated histone binding 16 1.63e-01 2.02e-01 6.64e-01
GO:0003756 protein disulfide isomerase activity 10 2.71e-01 -2.01e-01 7.34e-01
GO:0000132 establishment of mitotic spindle orientation 26 7.62e-02 -2.01e-01 5.62e-01
GO:0016829 lyase activity 15 1.78e-01 -2.01e-01 6.86e-01
GO:0097225 sperm midpiece 14 1.93e-01 -2.01e-01 6.92e-01
GO:0019722 calcium-mediated signaling 30 5.78e-02 2.00e-01 4.87e-01
GO:0044389 ubiquitin-like protein ligase binding 16 1.66e-01 -2.00e-01 6.68e-01
GO:0032007 negative regulation of TOR signaling 18 1.42e-01 2.00e-01 6.62e-01
GO:0072583 clathrin-dependent endocytosis 19 1.33e-01 1.99e-01 6.47e-01
GO:0031941 filamentous actin 18 1.43e-01 1.99e-01 6.62e-01
GO:0005743 mitochondrial inner membrane 180 4.28e-06 -1.99e-01 1.25e-03
GO:0008094 ATP-dependent activity, acting on DNA 11 2.53e-01 1.99e-01 7.28e-01
GO:0005112 Notch binding 13 2.15e-01 1.99e-01 6.96e-01
GO:0043542 endothelial cell migration 13 2.16e-01 1.98e-01 6.96e-01
GO:0048255 mRNA stabilization 16 1.73e-01 -1.97e-01 6.81e-01
GO:0031397 negative regulation of protein ubiquitination 33 5.05e-02 -1.97e-01 4.48e-01
GO:0032735 positive regulation of interleukin-12 production 12 2.39e-01 -1.96e-01 7.13e-01
GO:0000146 microfilament motor activity 18 1.49e-01 1.96e-01 6.62e-01
GO:0008286 insulin receptor signaling pathway 49 1.76e-02 1.96e-01 3.10e-01
GO:0007214 gamma-aminobutyric acid signaling pathway 11 2.61e-01 1.96e-01 7.31e-01
GO:0000145 exocyst 11 2.62e-01 1.95e-01 7.31e-01
GO:0051603 proteolysis involved in protein catabolic process 22 1.13e-01 -1.95e-01 6.06e-01
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 41 3.10e-02 -1.95e-01 3.64e-01
GO:0005834 heterotrimeric G-protein complex 19 1.43e-01 1.94e-01 6.62e-01
GO:0032585 multivesicular body membrane 12 2.45e-01 -1.94e-01 7.22e-01
GO:0032418 lysosome localization 23 1.08e-01 -1.94e-01 5.96e-01
GO:0008277 regulation of G protein-coupled receptor signaling pathway 16 1.80e-01 -1.93e-01 6.88e-01
GO:0000118 histone deacetylase complex 22 1.17e-01 1.93e-01 6.08e-01
GO:0022904 respiratory electron transport chain 14 2.12e-01 1.93e-01 6.96e-01
GO:0051028 mRNA transport 27 8.33e-02 -1.93e-01 5.86e-01
GO:0030036 actin cytoskeleton organization 107 5.93e-04 1.92e-01 6.95e-02
GO:0007098 centrosome cycle 17 1.70e-01 -1.92e-01 6.73e-01
GO:0035024 negative regulation of Rho protein signal transduction 14 2.13e-01 -1.92e-01 6.96e-01
GO:0030139 endocytic vesicle 37 4.34e-02 1.92e-01 4.31e-01
GO:0004364 glutathione transferase activity 10 2.94e-01 -1.92e-01 7.47e-01
GO:0005637 nuclear inner membrane 24 1.04e-01 -1.92e-01 5.96e-01
GO:0006936 muscle contraction 10 2.95e-01 1.91e-01 7.47e-01
GO:0019882 antigen processing and presentation 11 2.73e-01 -1.91e-01 7.37e-01
GO:0050728 negative regulation of inflammatory response 48 2.25e-02 -1.91e-01 3.42e-01
GO:0048839 inner ear development 12 2.53e-01 -1.91e-01 7.28e-01
GO:0070300 phosphatidic acid binding 13 2.34e-01 -1.91e-01 7.13e-01
GO:0051881 regulation of mitochondrial membrane potential 14 2.17e-01 -1.90e-01 6.97e-01
GO:0048146 positive regulation of fibroblast proliferation 19 1.51e-01 -1.90e-01 6.62e-01
GO:0072686 mitotic spindle 70 5.99e-03 -1.90e-01 1.94e-01
GO:0010842 retina layer formation 12 2.54e-01 1.90e-01 7.28e-01
GO:0043021 ribonucleoprotein complex binding 23 1.16e-01 -1.90e-01 6.08e-01
GO:0006376 mRNA splice site recognition 12 2.56e-01 1.89e-01 7.31e-01
GO:0007173 epidermal growth factor receptor signaling pathway 38 4.37e-02 1.89e-01 4.31e-01
GO:0006612 protein targeting to membrane 24 1.09e-01 1.89e-01 5.96e-01
GO:0034244 negative regulation of transcription elongation by RNA polymerase II 13 2.39e-01 -1.89e-01 7.13e-01
GO:0001764 neuron migration 38 4.45e-02 1.88e-01 4.31e-01
GO:0038061 non-canonical NF-kappaB signal transduction 11 2.79e-01 -1.88e-01 7.41e-01
GO:0051894 positive regulation of focal adhesion assembly 15 2.07e-01 1.88e-01 6.96e-01
GO:0071005 U2-type precatalytic spliceosome 31 7.03e-02 -1.88e-01 5.52e-01
GO:0050830 defense response to Gram-positive bacterium 15 2.08e-01 -1.88e-01 6.96e-01
GO:0120009 intermembrane lipid transfer 16 1.96e-01 -1.87e-01 6.94e-01
GO:0035855 megakaryocyte development 10 3.07e-01 -1.86e-01 7.48e-01
GO:0001937 negative regulation of endothelial cell proliferation 12 2.64e-01 -1.86e-01 7.32e-01
GO:0051457 maintenance of protein location in nucleus 10 3.07e-01 -1.86e-01 7.48e-01
GO:0006457 protein folding 81 3.81e-03 -1.86e-01 1.52e-01
GO:0005518 collagen binding 34 6.06e-02 1.86e-01 4.99e-01
GO:0001818 negative regulation of cytokine production 11 2.87e-01 1.85e-01 7.46e-01
GO:0008198 ferrous iron binding 12 2.68e-01 1.85e-01 7.32e-01
GO:0000398 mRNA splicing, via spliceosome 87 2.93e-03 -1.85e-01 1.36e-01
GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway 15 2.16e-01 1.85e-01 6.96e-01
GO:0060291 long-term synaptic potentiation 10 3.14e-01 1.84e-01 7.56e-01
GO:0097150 neuronal stem cell population maintenance 18 1.77e-01 1.84e-01 6.86e-01
GO:0038109 Kit signaling pathway 14 2.35e-01 1.83e-01 7.13e-01
GO:0030020 extracellular matrix structural constituent conferring tensile strength 16 2.05e-01 1.83e-01 6.96e-01
GO:0003727 single-stranded RNA binding 21 1.47e-01 1.83e-01 6.62e-01
GO:0001917 photoreceptor inner segment 22 1.38e-01 1.83e-01 6.55e-01
GO:0005903 brush border 17 1.93e-01 1.82e-01 6.92e-01
GO:0015914 phospholipid transport 26 1.07e-01 -1.82e-01 5.96e-01
GO:0031210 phosphatidylcholine binding 18 1.80e-01 -1.82e-01 6.88e-01
GO:0009792 embryo development ending in birth or egg hatching 10 3.19e-01 1.82e-01 7.61e-01
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 16 2.08e-01 -1.82e-01 6.96e-01
GO:0016460 myosin II complex 12 2.76e-01 1.82e-01 7.39e-01
GO:0042572 retinol metabolic process 13 2.59e-01 1.81e-01 7.31e-01
GO:0002062 chondrocyte differentiation 22 1.43e-01 1.81e-01 6.62e-01
GO:0061077 chaperone-mediated protein folding 16 2.12e-01 -1.80e-01 6.96e-01
GO:0007612 learning 13 2.61e-01 1.80e-01 7.31e-01
GO:0007623 circadian rhythm 18 1.87e-01 1.80e-01 6.90e-01
GO:0005759 mitochondrial matrix 119 7.42e-04 -1.79e-01 8.16e-02
GO:0043235 receptor complex 77 6.68e-03 1.79e-01 2.06e-01
GO:0060216 definitive hemopoiesis 10 3.28e-01 -1.79e-01 7.68e-01
GO:0031624 ubiquitin conjugating enzyme binding 17 2.04e-01 1.78e-01 6.96e-01
GO:0048870 cell motility 11 3.07e-01 -1.78e-01 7.48e-01
GO:0045190 isotype switching 13 2.67e-01 1.78e-01 7.32e-01
GO:0006396 RNA processing 21 1.60e-01 -1.77e-01 6.62e-01
GO:0048018 receptor ligand activity 18 1.94e-01 1.77e-01 6.92e-01
GO:0000266 mitochondrial fission 10 3.34e-01 -1.76e-01 7.72e-01
GO:0006351 DNA-templated transcription 36 6.79e-02 -1.76e-01 5.41e-01
GO:0035023 regulation of Rho protein signal transduction 16 2.23e-01 1.76e-01 7.06e-01
GO:0010634 positive regulation of epithelial cell migration 19 1.85e-01 1.76e-01 6.90e-01
GO:0050768 negative regulation of neurogenesis 10 3.37e-01 1.75e-01 7.72e-01
GO:0050839 cell adhesion molecule binding 21 1.64e-01 1.75e-01 6.67e-01
GO:0042472 inner ear morphogenesis 27 1.16e-01 -1.75e-01 6.08e-01
GO:0001223 transcription coactivator binding 22 1.56e-01 1.75e-01 6.62e-01
GO:0004722 protein serine/threonine phosphatase activity 33 8.32e-02 -1.74e-01 5.86e-01
GO:0008023 transcription elongation factor complex 14 2.59e-01 -1.74e-01 7.31e-01
GO:0045454 cell redox homeostasis 20 1.78e-01 -1.74e-01 6.86e-01
GO:0005791 rough endoplasmic reticulum 12 2.98e-01 -1.74e-01 7.47e-01
GO:0097730 non-motile cilium 15 2.46e-01 -1.73e-01 7.22e-01
GO:0035331 negative regulation of hippo signaling 18 2.05e-01 -1.73e-01 6.96e-01
GO:0005581 collagen trimer 17 2.18e-01 1.73e-01 6.97e-01
GO:1904646 cellular response to amyloid-beta 11 3.22e-01 1.73e-01 7.63e-01
GO:0030515 snoRNA binding 14 2.64e-01 -1.73e-01 7.32e-01
GO:0008233 peptidase activity 10 3.45e-01 -1.72e-01 7.79e-01
GO:0140588 chromatin looping 27 1.21e-01 1.72e-01 6.13e-01
GO:0043679 axon terminus 18 2.07e-01 1.72e-01 6.96e-01
GO:0001540 amyloid-beta binding 28 1.16e-01 -1.72e-01 6.08e-01
GO:0005004 GPI-linked ephrin receptor activity 12 3.04e-01 1.72e-01 7.47e-01
GO:0005011 macrophage colony-stimulating factor receptor activity 12 3.04e-01 1.72e-01 7.47e-01
GO:0005018 platelet-derived growth factor alpha-receptor activity 12 3.04e-01 1.72e-01 7.47e-01
GO:0005020 stem cell factor receptor activity 12 3.04e-01 1.72e-01 7.47e-01
GO:0008288 boss receptor activity 12 3.04e-01 1.72e-01 7.47e-01
GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway 12 3.04e-01 1.72e-01 7.47e-01
GO:0036323 vascular endothelial growth factor receptor-1 signaling pathway 12 3.04e-01 1.72e-01 7.47e-01
GO:0036332 placental growth factor receptor activity 12 3.04e-01 1.72e-01 7.47e-01
GO:0038145 macrophage colony-stimulating factor signaling pathway 12 3.04e-01 1.72e-01 7.47e-01
GO:0060175 brain-derived neurotrophic factor receptor activity 12 3.04e-01 1.72e-01 7.47e-01
GO:0005007 fibroblast growth factor receptor activity 13 2.84e-01 1.71e-01 7.44e-01
GO:0000070 mitotic sister chromatid segregation 18 2.09e-01 -1.71e-01 6.96e-01
GO:0016236 macroautophagy 16 2.37e-01 1.71e-01 7.13e-01
GO:0070411 I-SMAD binding 11 3.27e-01 1.71e-01 7.68e-01
GO:0001578 microtubule bundle formation 15 2.53e-01 1.71e-01 7.28e-01
GO:0005686 U2 snRNP 16 2.38e-01 -1.70e-01 7.13e-01
GO:0046627 negative regulation of insulin receptor signaling pathway 16 2.39e-01 -1.70e-01 7.13e-01
GO:0007017 microtubule-based process 11 3.31e-01 -1.69e-01 7.71e-01
GO:0032467 positive regulation of cytokinesis 14 2.73e-01 -1.69e-01 7.37e-01
GO:0017147 Wnt-protein binding 17 2.28e-01 1.69e-01 7.13e-01
GO:0035770 ribonucleoprotein granule 13 2.92e-01 -1.69e-01 7.47e-01
GO:0030687 preribosome, large subunit precursor 12 3.13e-01 -1.68e-01 7.53e-01
GO:1990841 promoter-specific chromatin binding 34 8.99e-02 1.68e-01 5.95e-01
GO:0030670 phagocytic vesicle membrane 19 2.06e-01 1.68e-01 6.96e-01
GO:1990518 single-stranded 3’-5’ DNA helicase activity 11 3.35e-01 1.68e-01 7.72e-01
GO:0012505 endomembrane system 97 4.43e-03 -1.67e-01 1.69e-01
GO:0001894 tissue homeostasis 13 2.97e-01 1.67e-01 7.47e-01
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 24 1.58e-01 1.66e-01 6.62e-01
GO:0006099 tricarboxylic acid cycle 19 2.10e-01 -1.66e-01 6.96e-01
GO:0060047 heart contraction 10 3.63e-01 -1.66e-01 7.88e-01
GO:0050699 WW domain binding 11 3.40e-01 -1.66e-01 7.75e-01
GO:0001784 phosphotyrosine residue binding 27 1.36e-01 1.66e-01 6.50e-01
GO:0032570 response to progesterone 13 3.02e-01 -1.65e-01 7.47e-01
GO:0042645 mitochondrial nucleoid 37 8.24e-02 -1.65e-01 5.86e-01
GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction 12 3.23e-01 -1.65e-01 7.63e-01
GO:0016235 aggresome 16 2.54e-01 -1.65e-01 7.28e-01
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 12 3.23e-01 -1.65e-01 7.63e-01
GO:0004714 transmembrane receptor protein tyrosine kinase activity 14 2.88e-01 1.64e-01 7.46e-01
GO:0042307 positive regulation of protein import into nucleus 25 1.57e-01 1.64e-01 6.62e-01
GO:0051480 regulation of cytosolic calcium ion concentration 13 3.08e-01 -1.63e-01 7.48e-01
GO:0060041 retina development in camera-type eye 20 2.06e-01 1.63e-01 6.96e-01
GO:0050750 low-density lipoprotein particle receptor binding 12 3.28e-01 1.63e-01 7.68e-01
GO:0061775 cohesin loader activity 24 1.67e-01 1.63e-01 6.71e-01
GO:0043010 camera-type eye development 22 1.87e-01 1.63e-01 6.90e-01
GO:1905168 positive regulation of double-strand break repair via homologous recombination 25 1.60e-01 -1.63e-01 6.62e-01
GO:0005085 guanyl-nucleotide exchange factor activity 143 8.34e-04 1.62e-01 8.51e-02
GO:0000281 mitotic cytokinesis 34 1.02e-01 -1.62e-01 5.96e-01
GO:0008360 regulation of cell shape 60 3.00e-02 1.62e-01 3.59e-01
GO:0006906 vesicle fusion 15 2.78e-01 -1.62e-01 7.40e-01
GO:0007492 endoderm development 10 3.77e-01 1.61e-01 7.90e-01
GO:0048009 insulin-like growth factor receptor signaling pathway 31 1.21e-01 1.61e-01 6.13e-01
GO:0005109 frizzled binding 18 2.37e-01 -1.61e-01 7.13e-01
GO:0071549 cellular response to dexamethasone stimulus 11 3.55e-01 1.61e-01 7.82e-01
GO:1901673 regulation of mitotic spindle assembly 16 2.66e-01 -1.61e-01 7.32e-01
GO:0009636 response to toxic substance 15 2.82e-01 1.60e-01 7.44e-01
GO:0070006 metalloaminopeptidase activity 15 2.84e-01 -1.60e-01 7.44e-01
GO:0001702 gastrulation with mouth forming second 10 3.82e-01 1.60e-01 7.90e-01
GO:0000151 ubiquitin ligase complex 48 5.63e-02 1.59e-01 4.83e-01
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 13 3.20e-01 -1.59e-01 7.61e-01
GO:0000956 nuclear-transcribed mRNA catabolic process 12 3.40e-01 1.59e-01 7.75e-01
GO:0008137 NADH dehydrogenase (ubiquinone) activity 10 3.84e-01 -1.59e-01 7.90e-01
GO:0034504 protein localization to nucleus 20 2.19e-01 -1.59e-01 7.00e-01
GO:0006488 dolichol-linked oligosaccharide biosynthetic process 14 3.04e-01 -1.59e-01 7.47e-01
GO:0030855 epithelial cell differentiation 29 1.40e-01 -1.59e-01 6.58e-01
GO:0038062 protein tyrosine kinase collagen receptor activity 13 3.23e-01 1.58e-01 7.63e-01
GO:0044322 endoplasmic reticulum quality control compartment 11 3.64e-01 1.58e-01 7.88e-01
GO:0008083 growth factor activity 38 9.29e-02 -1.58e-01 5.95e-01
GO:0001756 somitogenesis 24 1.83e-01 1.57e-01 6.90e-01
GO:0071479 cellular response to ionizing radiation 22 2.03e-01 1.57e-01 6.96e-01
GO:0009953 dorsal/ventral pattern formation 16 2.78e-01 -1.57e-01 7.40e-01
GO:0098982 GABA-ergic synapse 30 1.38e-01 -1.56e-01 6.55e-01
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 11 3.70e-01 1.56e-01 7.90e-01
GO:0000307 cyclin-dependent protein kinase holoenzyme complex 21 2.16e-01 -1.56e-01 6.97e-01
GO:0010507 negative regulation of autophagy 22 2.06e-01 1.56e-01 6.96e-01
GO:0070534 protein K63-linked ubiquitination 31 1.34e-01 -1.56e-01 6.47e-01
GO:0045296 cadherin binding 28 1.54e-01 1.56e-01 6.62e-01
GO:0071339 MLL1 complex 18 2.53e-01 1.56e-01 7.28e-01
GO:0050853 B cell receptor signaling pathway 19 2.42e-01 1.55e-01 7.17e-01
GO:0090398 cellular senescence 19 2.43e-01 -1.55e-01 7.19e-01
GO:0042742 defense response to bacterium 28 1.57e-01 -1.55e-01 6.62e-01
GO:0007369 gastrulation 10 3.98e-01 -1.54e-01 7.96e-01
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 13 3.36e-01 -1.54e-01 7.72e-01
GO:0044458 motile cilium assembly 12 3.57e-01 -1.54e-01 7.82e-01
GO:0032420 stereocilium 14 3.21e-01 -1.53e-01 7.62e-01
GO:0009653 anatomical structure morphogenesis 22 2.14e-01 1.53e-01 6.96e-01
GO:0000077 DNA damage checkpoint signaling 26 1.77e-01 -1.53e-01 6.86e-01
GO:0042552 myelination 27 1.69e-01 1.53e-01 6.73e-01
GO:0030133 transport vesicle 23 2.05e-01 -1.53e-01 6.96e-01
GO:0004896 cytokine receptor activity 19 2.51e-01 -1.52e-01 7.28e-01
GO:0000460 maturation of 5.8S rRNA 11 3.83e-01 -1.52e-01 7.90e-01
GO:0045824 negative regulation of innate immune response 16 2.93e-01 -1.52e-01 7.47e-01
GO:0140584 chromatin extrusion motor activity 23 2.08e-01 1.52e-01 6.96e-01
GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 23 2.08e-01 1.52e-01 6.96e-01
GO:0140849 ATP-dependent H2AZ histone chaperone activity 23 2.08e-01 1.52e-01 6.96e-01
GO:0003713 transcription coactivator activity 128 3.06e-03 1.52e-01 1.38e-01
GO:0003899 DNA-directed 5’-3’ RNA polymerase activity 10 4.06e-01 -1.52e-01 7.99e-01
GO:0006334 nucleosome assembly 27 1.74e-01 1.51e-01 6.81e-01
GO:0030742 GTP-dependent protein binding 13 3.47e-01 -1.51e-01 7.80e-01
GO:0007346 regulation of mitotic cell cycle 31 1.47e-01 -1.50e-01 6.62e-01
GO:0043153 entrainment of circadian clock by photoperiod 13 3.49e-01 -1.50e-01 7.80e-01
GO:0009952 anterior/posterior pattern specification 41 9.71e-02 -1.50e-01 5.95e-01
GO:0030317 flagellated sperm motility 28 1.70e-01 -1.50e-01 6.73e-01
GO:0038084 vascular endothelial growth factor signaling pathway 23 2.14e-01 1.50e-01 6.96e-01
GO:0005771 multivesicular body 21 2.35e-01 -1.50e-01 7.13e-01
GO:0007611 learning or memory 15 3.16e-01 1.49e-01 7.57e-01
GO:0005008 hepatocyte growth factor receptor activity 13 3.51e-01 1.49e-01 7.80e-01
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment 36 1.21e-01 -1.49e-01 6.13e-01
GO:0000380 alternative mRNA splicing, via spliceosome 16 3.02e-01 -1.49e-01 7.47e-01
GO:0045165 cell fate commitment 21 2.40e-01 -1.48e-01 7.14e-01
GO:2000352 negative regulation of endothelial cell apoptotic process 14 3.37e-01 -1.48e-01 7.72e-01
GO:0030032 lamellipodium assembly 20 2.52e-01 1.48e-01 7.28e-01
GO:0031122 cytoplasmic microtubule organization 28 1.75e-01 1.48e-01 6.84e-01
GO:0035979 histone H2AXS139 kinase activity 32 1.48e-01 1.48e-01 6.62e-01
GO:0051781 positive regulation of cell division 12 3.75e-01 -1.48e-01 7.90e-01
GO:0004679 AMP-activated protein kinase activity 32 1.49e-01 1.47e-01 6.62e-01
GO:0006611 protein export from nucleus 22 2.32e-01 -1.47e-01 7.13e-01
GO:0090734 site of DNA damage 22 2.32e-01 -1.47e-01 7.13e-01
GO:0006913 nucleocytoplasmic transport 18 2.80e-01 -1.47e-01 7.41e-01
GO:0030658 transport vesicle membrane 13 3.59e-01 1.47e-01 7.85e-01
GO:0005681 spliceosomal complex 43 9.60e-02 -1.47e-01 5.95e-01
GO:0045862 positive regulation of proteolysis 12 3.79e-01 -1.47e-01 7.90e-01
GO:0098609 cell-cell adhesion 81 2.26e-02 1.47e-01 3.42e-01
GO:0006882 intracellular zinc ion homeostasis 12 3.79e-01 -1.47e-01 7.90e-01
GO:0007416 synapse assembly 25 2.05e-01 1.46e-01 6.96e-01
GO:0034067 protein localization to Golgi apparatus 12 3.80e-01 1.46e-01 7.90e-01
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 32 1.52e-01 1.46e-01 6.62e-01
GO:0005385 zinc ion transmembrane transporter activity 15 3.28e-01 -1.46e-01 7.68e-01
GO:0005879 axonemal microtubule 10 4.25e-01 -1.46e-01 8.15e-01
GO:0046854 phosphatidylinositol phosphate biosynthetic process 18 2.85e-01 -1.46e-01 7.44e-01
GO:0004842 ubiquitin-protein transferase activity 65 4.29e-02 1.45e-01 4.31e-01
GO:0070063 RNA polymerase binding 12 3.84e-01 1.45e-01 7.90e-01
GO:0006506 GPI anchor biosynthetic process 25 2.10e-01 1.45e-01 6.96e-01
GO:0001968 fibronectin binding 10 4.28e-01 1.45e-01 8.16e-01
GO:0007268 chemical synaptic transmission 33 1.51e-01 -1.44e-01 6.62e-01
GO:0030496 midbody 99 1.31e-02 -1.44e-01 2.73e-01
GO:0051539 4 iron, 4 sulfur cluster binding 33 1.52e-01 -1.44e-01 6.62e-01
GO:0031507 heterochromatin formation 27 1.95e-01 -1.44e-01 6.94e-01
GO:0060348 bone development 26 2.04e-01 1.44e-01 6.96e-01
GO:0140627 ubiquitin-dependent protein catabolic process via the C-end degron rule pathway 10 4.31e-01 1.44e-01 8.19e-01
GO:0048872 homeostasis of number of cells 14 3.52e-01 1.44e-01 7.80e-01
GO:0017025 TBP-class protein binding 18 2.92e-01 1.43e-01 7.47e-01
GO:0005884 actin filament 43 1.04e-01 1.43e-01 5.96e-01
GO:0016579 protein deubiquitination 28 1.89e-01 1.43e-01 6.91e-01
GO:0071168 protein localization to chromatin 17 3.08e-01 -1.43e-01 7.48e-01
GO:0000775 chromosome, centromeric region 31 1.70e-01 -1.42e-01 6.73e-01
GO:0005484 SNAP receptor activity 26 2.10e-01 -1.42e-01 6.96e-01
GO:0001958 endochondral ossification 15 3.42e-01 1.42e-01 7.75e-01
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 19 2.85e-01 -1.42e-01 7.44e-01
GO:0008154 actin polymerization or depolymerization 11 4.16e-01 -1.42e-01 8.04e-01
GO:0016779 nucleotidyltransferase activity 11 4.16e-01 -1.42e-01 8.04e-01
GO:0032587 ruffle membrane 41 1.17e-01 1.41e-01 6.08e-01
GO:0006468 protein phosphorylation 12 3.96e-01 -1.41e-01 7.96e-01
GO:0070064 proline-rich region binding 10 4.39e-01 1.41e-01 8.23e-01
GO:0036464 cytoplasmic ribonucleoprotein granule 37 1.37e-01 -1.41e-01 6.55e-01
GO:0005044 scavenger receptor activity 10 4.42e-01 -1.41e-01 8.24e-01
GO:0005102 signaling receptor binding 81 2.90e-02 -1.40e-01 3.59e-01
GO:0035615 clathrin adaptor activity 10 4.43e-01 -1.40e-01 8.24e-01
GO:0000149 SNARE binding 31 1.78e-01 -1.40e-01 6.86e-01
GO:0030424 axon 119 8.47e-03 1.40e-01 2.38e-01
GO:0030041 actin filament polymerization 16 3.33e-01 -1.40e-01 7.72e-01
GO:0042274 ribosomal small subunit biogenesis 44 1.09e-01 -1.40e-01 5.96e-01
GO:0002053 positive regulation of mesenchymal cell proliferation 11 4.23e-01 -1.40e-01 8.13e-01
GO:0045184 establishment of protein localization 17 3.20e-01 1.39e-01 7.61e-01
GO:0010811 positive regulation of cell-substrate adhesion 13 3.85e-01 1.39e-01 7.90e-01
GO:0051787 misfolded protein binding 12 4.04e-01 1.39e-01 7.97e-01
GO:0042813 Wnt receptor activity 12 4.04e-01 1.39e-01 7.97e-01
GO:0008203 cholesterol metabolic process 30 1.88e-01 1.39e-01 6.90e-01
GO:0016363 nuclear matrix 46 1.04e-01 -1.39e-01 5.96e-01
GO:0046856 phosphatidylinositol dephosphorylation 26 2.22e-01 1.39e-01 7.03e-01
GO:0042162 telomeric DNA binding 20 2.84e-01 1.38e-01 7.44e-01
GO:0010569 regulation of double-strand break repair via homologous recombination 10 4.49e-01 -1.38e-01 8.29e-01
GO:0060173 limb development 23 2.52e-01 -1.38e-01 7.28e-01
GO:0006891 intra-Golgi vesicle-mediated transport 18 3.11e-01 -1.38e-01 7.52e-01
GO:0061564 axon development 13 3.89e-01 -1.38e-01 7.95e-01
GO:0098793 presynapse 63 6.05e-02 -1.37e-01 4.99e-01
GO:0070403 NAD+ binding 11 4.33e-01 -1.37e-01 8.22e-01
GO:0030522 intracellular receptor signaling pathway 18 3.16e-01 -1.36e-01 7.57e-01
GO:0031290 retinal ganglion cell axon guidance 11 4.34e-01 -1.36e-01 8.22e-01
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 23 2.59e-01 1.36e-01 7.31e-01
GO:0016323 basolateral plasma membrane 94 2.30e-02 1.36e-01 3.42e-01
GO:0050766 positive regulation of phagocytosis 14 3.79e-01 -1.36e-01 7.90e-01
GO:0048741 skeletal muscle fiber development 16 3.47e-01 1.36e-01 7.80e-01
GO:0007032 endosome organization 28 2.15e-01 1.35e-01 6.96e-01
GO:0010824 regulation of centrosome duplication 15 3.66e-01 -1.35e-01 7.88e-01
GO:0019888 protein phosphatase regulator activity 16 3.50e-01 1.35e-01 7.80e-01
GO:0032496 response to lipopolysaccharide 37 1.56e-01 -1.35e-01 6.62e-01
GO:0072593 reactive oxygen species metabolic process 15 3.66e-01 1.35e-01 7.88e-01
GO:0030837 negative regulation of actin filament polymerization 14 3.83e-01 -1.35e-01 7.90e-01
GO:0007095 mitotic G2 DNA damage checkpoint signaling 30 2.02e-01 1.35e-01 6.96e-01
GO:0000049 tRNA binding 52 9.36e-02 -1.34e-01 5.95e-01
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 66 5.91e-02 -1.34e-01 4.92e-01
GO:0071277 cellular response to calcium ion 32 1.88e-01 -1.34e-01 6.90e-01
GO:0048012 hepatocyte growth factor receptor signaling pathway 17 3.38e-01 1.34e-01 7.72e-01
GO:0007411 axon guidance 76 4.31e-02 1.34e-01 4.31e-01
GO:0051085 chaperone cofactor-dependent protein refolding 23 2.65e-01 -1.34e-01 7.32e-01
GO:0004677 DNA-dependent protein kinase activity 31 1.96e-01 1.34e-01 6.94e-01
GO:0000423 mitophagy 32 1.89e-01 -1.34e-01 6.91e-01
GO:0070830 bicellular tight junction assembly 19 3.12e-01 -1.34e-01 7.53e-01
GO:0042060 wound healing 28 2.20e-01 1.34e-01 7.00e-01
GO:0030018 Z disc 48 1.09e-01 1.34e-01 5.96e-01
GO:0051020 GTPase binding 15 3.70e-01 1.34e-01 7.90e-01
GO:0007628 adult walking behavior 13 4.04e-01 1.34e-01 7.97e-01
GO:1904294 positive regulation of ERAD pathway 10 4.65e-01 -1.34e-01 8.38e-01
GO:0061136 regulation of proteasomal protein catabolic process 11 4.43e-01 -1.34e-01 8.24e-01
GO:0005080 protein kinase C binding 16 3.57e-01 -1.33e-01 7.82e-01
GO:0048306 calcium-dependent protein binding 20 3.04e-01 -1.33e-01 7.47e-01
GO:0000082 G1/S transition of mitotic cell cycle 40 1.46e-01 -1.33e-01 6.62e-01
GO:0051560 mitochondrial calcium ion homeostasis 13 4.08e-01 -1.33e-01 8.00e-01
GO:0008283 cell population proliferation 65 6.49e-02 1.33e-01 5.26e-01
GO:2000300 regulation of synaptic vesicle exocytosis 18 3.31e-01 -1.32e-01 7.71e-01
GO:0045600 positive regulation of fat cell differentiation 21 2.94e-01 -1.32e-01 7.47e-01
GO:0030833 regulation of actin filament polymerization 21 2.95e-01 -1.32e-01 7.47e-01
GO:0040018 positive regulation of multicellular organism growth 16 3.61e-01 1.32e-01 7.85e-01
GO:0060079 excitatory postsynaptic potential 15 3.78e-01 -1.31e-01 7.90e-01
GO:1904262 negative regulation of TORC1 signaling 28 2.29e-01 1.31e-01 7.13e-01
GO:0000993 RNA polymerase II complex binding 23 2.76e-01 -1.31e-01 7.39e-01
GO:0043240 Fanconi anaemia nuclear complex 11 4.51e-01 -1.31e-01 8.29e-01
GO:0048013 ephrin receptor signaling pathway 24 2.68e-01 1.31e-01 7.32e-01
GO:0000400 four-way junction DNA binding 14 3.99e-01 -1.30e-01 7.96e-01
GO:0032743 positive regulation of interleukin-2 production 16 3.68e-01 -1.30e-01 7.88e-01
GO:2000737 negative regulation of stem cell differentiation 12 4.36e-01 -1.30e-01 8.22e-01
GO:0030159 signaling receptor complex adaptor activity 13 4.18e-01 1.30e-01 8.04e-01
GO:0000786 nucleosome 16 3.69e-01 1.30e-01 7.90e-01
GO:0006955 immune response 42 1.46e-01 -1.30e-01 6.62e-01
GO:0032968 positive regulation of transcription elongation by RNA polymerase II 15 3.85e-01 -1.30e-01 7.90e-01
GO:0043015 gamma-tubulin binding 21 3.07e-01 -1.29e-01 7.48e-01
GO:0048538 thymus development 22 2.96e-01 1.29e-01 7.47e-01
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway 28 2.39e-01 1.29e-01 7.13e-01
GO:0098686 hippocampal mossy fiber to CA3 synapse 18 3.45e-01 1.29e-01 7.78e-01
GO:0060586 multicellular organismal-level iron ion homeostasis 16 3.73e-01 1.29e-01 7.90e-01
GO:0001755 neural crest cell migration 23 2.88e-01 1.28e-01 7.46e-01
GO:0071480 cellular response to gamma radiation 14 4.08e-01 -1.28e-01 8.00e-01
GO:0007601 visual perception 37 1.80e-01 1.27e-01 6.88e-01
GO:0006493 protein O-linked glycosylation 30 2.28e-01 1.27e-01 7.13e-01
GO:0071889 14-3-3 protein binding 15 3.94e-01 -1.27e-01 7.96e-01
GO:0032008 positive regulation of TOR signaling 12 4.46e-01 -1.27e-01 8.27e-01
GO:0046716 muscle cell cellular homeostasis 15 3.95e-01 1.27e-01 7.96e-01
GO:0061608 nuclear import signal receptor activity 14 4.11e-01 1.27e-01 8.03e-01
GO:0030178 negative regulation of Wnt signaling pathway 17 3.66e-01 1.27e-01 7.88e-01
GO:0007026 negative regulation of microtubule depolymerization 17 3.66e-01 1.27e-01 7.88e-01
GO:0010719 negative regulation of epithelial to mesenchymal transition 16 3.81e-01 -1.27e-01 7.90e-01
GO:0030276 clathrin binding 17 3.66e-01 1.27e-01 7.88e-01
GO:0042149 cellular response to glucose starvation 29 2.39e-01 1.26e-01 7.13e-01
GO:0051393 alpha-actinin binding 10 4.89e-01 1.26e-01 8.54e-01
GO:0005938 cell cortex 74 6.07e-02 1.26e-01 4.99e-01
GO:0046326 positive regulation of D-glucose import 14 4.15e-01 1.26e-01 8.04e-01
GO:0090543 Flemming body 14 4.15e-01 -1.26e-01 8.04e-01
GO:0005643 nuclear pore 33 2.11e-01 -1.26e-01 6.96e-01
GO:0008584 male gonad development 28 2.51e-01 -1.25e-01 7.28e-01
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle 26 2.69e-01 1.25e-01 7.32e-01
GO:0032580 Golgi cisterna membrane 27 2.60e-01 -1.25e-01 7.31e-01
GO:0004879 nuclear receptor activity 39 1.76e-01 -1.25e-01 6.86e-01
GO:0006915 apoptotic process 135 1.22e-02 -1.25e-01 2.73e-01
GO:0070372 regulation of ERK1 and ERK2 cascade 12 4.55e-01 1.25e-01 8.29e-01
GO:0043113 receptor clustering 13 4.37e-01 1.25e-01 8.22e-01
GO:0045815 transcription initiation-coupled chromatin remodeling 20 3.35e-01 1.25e-01 7.72e-01
GO:0097190 apoptotic signaling pathway 20 3.36e-01 -1.24e-01 7.72e-01
GO:0070971 endoplasmic reticulum exit site 19 3.49e-01 1.24e-01 7.80e-01
GO:0007030 Golgi organization 62 9.15e-02 -1.24e-01 5.95e-01
GO:0003887 DNA-directed DNA polymerase activity 16 3.91e-01 1.24e-01 7.95e-01
GO:0003678 DNA helicase activity 20 3.38e-01 1.24e-01 7.72e-01
GO:1903077 negative regulation of protein localization to plasma membrane 13 4.40e-01 1.24e-01 8.23e-01
GO:0034727 piecemeal microautophagy of the nucleus 13 4.41e-01 1.23e-01 8.24e-01
GO:0004676 3-phosphoinositide-dependent protein kinase activity 31 2.35e-01 1.23e-01 7.13e-01
GO:0140823 histone H2BS36 kinase activity 31 2.36e-01 1.23e-01 7.13e-01
GO:1901223 negative regulation of non-canonical NF-kappaB signal transduction 14 4.26e-01 -1.23e-01 8.15e-01
GO:0051131 chaperone-mediated protein complex assembly 14 4.26e-01 -1.23e-01 8.15e-01
GO:0031012 extracellular matrix 90 4.42e-02 1.23e-01 4.31e-01
GO:0040029 epigenetic regulation of gene expression 18 3.68e-01 -1.23e-01 7.88e-01
GO:0051301 cell division 144 1.12e-02 -1.23e-01 2.59e-01
GO:0046332 SMAD binding 23 3.09e-01 1.23e-01 7.48e-01
GO:0045292 mRNA cis splicing, via spliceosome 13 4.44e-01 -1.23e-01 8.24e-01
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 40 1.80e-01 -1.23e-01 6.88e-01
GO:0097431 mitotic spindle pole 27 2.71e-01 -1.22e-01 7.34e-01
GO:0015629 actin cytoskeleton 111 2.62e-02 1.22e-01 3.59e-01
GO:0003714 transcription corepressor activity 101 3.39e-02 1.22e-01 3.80e-01
GO:0001675 acrosome assembly 11 4.84e-01 -1.22e-01 8.50e-01
GO:0071897 DNA biosynthetic process 12 4.65e-01 1.22e-01 8.38e-01
GO:0003743 translation initiation factor activity 39 1.90e-01 -1.21e-01 6.91e-01
GO:0006275 regulation of DNA replication 24 3.06e-01 -1.21e-01 7.48e-01
GO:0001618 virus receptor activity 10 5.10e-01 1.20e-01 8.62e-01
GO:0050769 positive regulation of neurogenesis 12 4.70e-01 1.20e-01 8.42e-01
GO:0005667 transcription regulator complex 91 4.74e-02 1.20e-01 4.35e-01
GO:0016301 kinase activity 14 4.37e-01 -1.20e-01 8.22e-01
GO:0048041 focal adhesion assembly 14 4.39e-01 1.20e-01 8.23e-01
GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 17 3.94e-01 1.20e-01 7.96e-01
GO:0016239 positive regulation of macroautophagy 17 3.94e-01 1.19e-01 7.96e-01
GO:0008104 protein localization 66 9.35e-02 -1.19e-01 5.95e-01
GO:0032760 positive regulation of tumor necrosis factor production 33 2.36e-01 1.19e-01 7.13e-01
GO:0005682 U5 snRNP 10 5.14e-01 1.19e-01 8.65e-01
GO:0010976 positive regulation of neuron projection development 30 2.59e-01 -1.19e-01 7.31e-01
GO:0015631 tubulin binding 27 2.84e-01 -1.19e-01 7.44e-01
GO:0005856 cytoskeleton 174 6.86e-03 1.19e-01 2.08e-01
GO:0030334 regulation of cell migration 35 2.24e-01 1.19e-01 7.06e-01
GO:0006338 chromatin remodeling 249 1.28e-03 1.19e-01 1.03e-01
GO:0006364 rRNA processing 65 9.79e-02 -1.19e-01 5.95e-01
GO:0006805 xenobiotic metabolic process 17 3.97e-01 1.19e-01 7.96e-01
GO:0031466 Cul5-RING ubiquitin ligase complex 11 4.96e-01 -1.19e-01 8.61e-01
GO:0030175 filopodium 29 2.69e-01 1.19e-01 7.32e-01
GO:0060090 molecular adaptor activity 75 7.67e-02 1.18e-01 5.62e-01
GO:0045499 chemorepellent activity 16 4.13e-01 1.18e-01 8.04e-01
GO:0031334 positive regulation of protein-containing complex assembly 17 3.99e-01 1.18e-01 7.96e-01
GO:0010592 positive regulation of lamellipodium assembly 10 5.18e-01 1.18e-01 8.65e-01
GO:0140801 histone H2AXY142 kinase activity 22 3.42e-01 1.17e-01 7.75e-01
GO:0009566 fertilization 12 4.83e-01 -1.17e-01 8.50e-01
GO:0032154 cleavage furrow 28 2.85e-01 -1.17e-01 7.44e-01
GO:0030163 protein catabolic process 31 2.63e-01 -1.16e-01 7.32e-01
GO:0005770 late endosome 74 8.42e-02 1.16e-01 5.86e-01
GO:0051302 regulation of cell division 11 5.06e-01 -1.16e-01 8.62e-01
GO:0007218 neuropeptide signaling pathway 16 4.24e-01 1.15e-01 8.15e-01
GO:0071300 cellular response to retinoic acid 17 4.11e-01 -1.15e-01 8.03e-01
GO:0015701 bicarbonate transport 11 5.09e-01 -1.15e-01 8.62e-01
GO:0070373 negative regulation of ERK1 and ERK2 cascade 30 2.77e-01 1.15e-01 7.40e-01
GO:0006397 mRNA processing 72 9.29e-02 -1.15e-01 5.95e-01
GO:0005739 mitochondrion 607 1.72e-06 -1.15e-01 6.04e-04
GO:0016459 myosin complex 22 3.53e-01 1.14e-01 7.81e-01
GO:0006268 DNA unwinding involved in DNA replication 14 4.59e-01 1.14e-01 8.34e-01
GO:0101031 protein folding chaperone complex 18 4.02e-01 -1.14e-01 7.97e-01
GO:0098719 sodium ion import across plasma membrane 10 5.33e-01 -1.14e-01 8.72e-01
GO:0034220 monoatomic ion transmembrane transport 20 3.78e-01 1.14e-01 7.90e-01
GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 10 5.34e-01 1.14e-01 8.72e-01
GO:0062023 collagen-containing extracellular matrix 71 9.89e-02 1.13e-01 5.95e-01
GO:0006641 triglyceride metabolic process 10 5.35e-01 -1.13e-01 8.72e-01
GO:0000794 condensed nuclear chromosome 20 3.82e-01 -1.13e-01 7.90e-01
GO:0030521 androgen receptor signaling pathway 12 4.99e-01 -1.13e-01 8.61e-01
GO:0030509 BMP signaling pathway 38 2.30e-01 1.13e-01 7.13e-01
GO:0017116 single-stranded DNA helicase activity 16 4.36e-01 1.12e-01 8.22e-01
GO:0060236 regulation of mitotic spindle organization 12 5.01e-01 1.12e-01 8.61e-01
GO:0051642 centrosome localization 14 4.68e-01 -1.12e-01 8.40e-01
GO:0043065 positive regulation of apoptotic process 121 3.34e-02 -1.12e-01 3.80e-01
GO:0051087 protein-folding chaperone binding 55 1.52e-01 -1.12e-01 6.62e-01
GO:0046847 filopodium assembly 10 5.42e-01 -1.11e-01 8.74e-01
GO:0032993 protein-DNA complex 21 3.78e-01 -1.11e-01 7.90e-01
GO:0050661 NADP binding 15 4.56e-01 1.11e-01 8.30e-01
GO:0072518 Rho-dependent protein serine/threonine kinase activity 32 2.77e-01 1.11e-01 7.39e-01
GO:0045727 positive regulation of translation 36 2.51e-01 -1.11e-01 7.28e-01
GO:0035116 embryonic hindlimb morphogenesis 11 5.25e-01 -1.11e-01 8.70e-01
GO:0032588 trans-Golgi network membrane 26 3.30e-01 -1.10e-01 7.70e-01
GO:0005179 hormone activity 12 5.08e-01 -1.10e-01 8.62e-01
GO:0008237 metallopeptidase activity 12 5.09e-01 1.10e-01 8.62e-01
GO:0045995 regulation of embryonic development 27 3.22e-01 -1.10e-01 7.63e-01
GO:0043024 ribosomal small subunit binding 13 4.94e-01 -1.10e-01 8.59e-01
GO:0048873 homeostasis of number of cells within a tissue 14 4.78e-01 1.09e-01 8.50e-01
GO:0007254 JNK cascade 25 3.44e-01 -1.09e-01 7.78e-01
GO:0005868 cytoplasmic dynein complex 14 4.79e-01 1.09e-01 8.50e-01
GO:0060339 negative regulation of type I interferon-mediated signaling pathway 13 4.98e-01 -1.09e-01 8.61e-01
GO:0005005 transmembrane-ephrin receptor activity 14 4.82e-01 1.09e-01 8.50e-01
GO:0008047 enzyme activator activity 15 4.67e-01 1.09e-01 8.39e-01
GO:0007131 reciprocal meiotic recombination 12 5.15e-01 -1.09e-01 8.65e-01
GO:0035402 histone H3T11 kinase activity 30 3.04e-01 1.08e-01 7.47e-01
GO:0044022 histone H3S28 kinase activity 30 3.04e-01 1.08e-01 7.47e-01
GO:0044023 histone H4S1 kinase activity 30 3.04e-01 1.08e-01 7.47e-01
GO:0044024 histone H2AS1 kinase activity 30 3.04e-01 1.08e-01 7.47e-01
GO:0044025 histone H2BS14 kinase activity 30 3.04e-01 1.08e-01 7.47e-01
GO:0072371 histone H2AS121 kinase activity 30 3.04e-01 1.08e-01 7.47e-01
GO:0140855 histone H3S57 kinase activity 30 3.04e-01 1.08e-01 7.47e-01
GO:0140857 histone H3T45 kinase activity 30 3.04e-01 1.08e-01 7.47e-01
GO:0061024 membrane organization 13 4.99e-01 -1.08e-01 8.61e-01
GO:0008340 determination of adult lifespan 21 3.90e-01 -1.08e-01 7.95e-01
GO:0014704 intercalated disc 13 5.00e-01 1.08e-01 8.61e-01
GO:0051219 phosphoprotein binding 20 4.03e-01 1.08e-01 7.97e-01
GO:0008654 phospholipid biosynthetic process 12 5.18e-01 -1.08e-01 8.65e-01
GO:0045880 positive regulation of smoothened signaling pathway 22 3.82e-01 -1.08e-01 7.90e-01
GO:0050804 modulation of chemical synaptic transmission 35 2.71e-01 1.08e-01 7.34e-01
GO:0035267 NuA4 histone acetyltransferase complex 18 4.30e-01 1.08e-01 8.17e-01
GO:1990904 ribonucleoprotein complex 104 5.87e-02 -1.07e-01 4.91e-01
GO:0002376 immune system process 13 5.03e-01 1.07e-01 8.61e-01
GO:0004843 cysteine-type deubiquitinase activity 57 1.63e-01 1.07e-01 6.64e-01
GO:0004725 protein tyrosine phosphatase activity 44 2.20e-01 1.07e-01 7.00e-01
GO:0045747 positive regulation of Notch signaling pathway 23 3.75e-01 1.07e-01 7.90e-01
GO:0048812 neuron projection morphogenesis 29 3.20e-01 1.07e-01 7.61e-01
GO:0001503 ossification 25 3.56e-01 1.07e-01 7.82e-01
GO:0051592 response to calcium ion 20 4.12e-01 1.06e-01 8.03e-01
GO:0035401 histone H3Y41 kinase activity 21 4.00e-01 1.06e-01 7.97e-01
GO:0006783 heme biosynthetic process 10 5.62e-01 -1.06e-01 8.79e-01
GO:0006869 lipid transport 26 3.51e-01 1.06e-01 7.80e-01
GO:0007608 sensory perception of smell 11 5.44e-01 1.06e-01 8.76e-01
GO:0070131 positive regulation of mitochondrial translation 10 5.64e-01 -1.05e-01 8.79e-01
GO:0003151 outflow tract morphogenesis 19 4.27e-01 -1.05e-01 8.15e-01
GO:0007204 positive regulation of cytosolic calcium ion concentration 18 4.40e-01 1.05e-01 8.23e-01
GO:0007042 lysosomal lumen acidification 10 5.65e-01 -1.05e-01 8.79e-01
GO:0000723 telomere maintenance 29 3.28e-01 1.05e-01 7.68e-01
GO:0034394 protein localization to cell surface 17 4.54e-01 -1.05e-01 8.29e-01
GO:0006417 regulation of translation 44 2.31e-01 -1.04e-01 7.13e-01
GO:0035175 histone H3S10 kinase activity 31 3.15e-01 1.04e-01 7.56e-01
GO:0072354 histone H3T3 kinase activity 31 3.15e-01 1.04e-01 7.56e-01
GO:0016887 ATP hydrolysis activity 214 8.75e-03 1.04e-01 2.38e-01
GO:0048167 regulation of synaptic plasticity 15 4.85e-01 -1.04e-01 8.50e-01
GO:1902476 chloride transmembrane transport 39 2.61e-01 1.04e-01 7.31e-01
GO:0046676 negative regulation of insulin secretion 10 5.70e-01 -1.04e-01 8.81e-01
GO:0046718 symbiont entry into host cell 22 4.00e-01 1.04e-01 7.97e-01
GO:0030307 positive regulation of cell growth 36 2.83e-01 -1.03e-01 7.44e-01
GO:0005540 hyaluronic acid binding 13 5.19e-01 -1.03e-01 8.65e-01
GO:0032508 DNA duplex unwinding 44 2.37e-01 1.03e-01 7.13e-01
GO:0001947 heart looping 23 3.93e-01 -1.03e-01 7.96e-01
GO:0015026 coreceptor activity 13 5.20e-01 1.03e-01 8.66e-01
GO:0150052 regulation of postsynapse assembly 12 5.38e-01 -1.03e-01 8.73e-01
GO:0008327 methyl-CpG binding 16 4.80e-01 -1.02e-01 8.50e-01
GO:0001669 acrosomal vesicle 26 3.68e-01 1.02e-01 7.88e-01
GO:0007368 determination of left/right symmetry 28 3.50e-01 -1.02e-01 7.80e-01
GO:0042605 peptide antigen binding 10 5.77e-01 -1.02e-01 8.85e-01
GO:0070847 core mediator complex 19 4.42e-01 -1.02e-01 8.24e-01
GO:0006355 regulation of DNA-templated transcription 159 2.70e-02 1.02e-01 3.59e-01
GO:0006406 mRNA export from nucleus 28 3.51e-01 1.02e-01 7.80e-01
GO:0043488 regulation of mRNA stability 16 4.81e-01 1.02e-01 8.50e-01
GO:0045821 positive regulation of glycolytic process 10 5.78e-01 1.02e-01 8.85e-01
GO:0000792 heterochromatin 19 4.43e-01 -1.02e-01 8.24e-01
GO:0140662 ATP-dependent protein folding chaperone 23 3.99e-01 -1.02e-01 7.96e-01
GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction 35 2.99e-01 1.02e-01 7.47e-01
GO:0019706 protein-cysteine S-palmitoyltransferase activity 17 4.69e-01 1.01e-01 8.40e-01
GO:0006325 chromatin organization 66 1.55e-01 1.01e-01 6.62e-01
GO:0071346 cellular response to type II interferon 24 3.91e-01 -1.01e-01 7.96e-01
GO:0006886 intracellular protein transport 158 2.90e-02 -1.01e-01 3.59e-01
GO:0071539 protein localization to centrosome 20 4.35e-01 1.01e-01 8.22e-01
GO:0060324 face development 14 5.14e-01 1.01e-01 8.65e-01
GO:0031929 TOR signaling 13 5.31e-01 -1.00e-01 8.71e-01
GO:0045214 sarcomere organization 12 5.47e-01 1.00e-01 8.76e-01
GO:0048536 spleen development 23 4.06e-01 -1.00e-01 7.99e-01
GO:0001222 transcription corepressor binding 27 3.68e-01 -1.00e-01 7.88e-01
GO:0003730 mRNA 3’-UTR binding 51 2.18e-01 9.99e-02 6.97e-01
GO:0071782 endoplasmic reticulum tubular network 12 5.49e-01 9.98e-02 8.77e-01
GO:0003779 actin binding 137 4.48e-02 9.95e-02 4.31e-01
GO:0071944 cell periphery 12 5.52e-01 -9.93e-02 8.77e-01
GO:0000278 mitotic cell cycle 53 2.12e-01 -9.91e-02 6.96e-01
GO:0038023 signaling receptor activity 41 2.74e-01 9.87e-02 7.39e-01
GO:0031418 L-ascorbic acid binding 14 5.24e-01 9.85e-02 8.70e-01
GO:0006487 protein N-linked glycosylation 30 3.52e-01 -9.83e-02 7.80e-01
GO:0005657 replication fork 20 4.48e-01 -9.81e-02 8.27e-01
GO:0045668 negative regulation of osteoblast differentiation 27 3.78e-01 -9.81e-02 7.90e-01
GO:0042734 presynaptic membrane 36 3.09e-01 9.80e-02 7.48e-01
GO:0009060 aerobic respiration 10 5.92e-01 9.80e-02 8.90e-01
GO:0000922 spindle pole 69 1.60e-01 -9.79e-02 6.62e-01
GO:0030100 regulation of endocytosis 12 5.57e-01 9.78e-02 8.78e-01
GO:0007275 multicellular organism development 26 3.88e-01 9.78e-02 7.95e-01
GO:0006605 protein targeting 18 4.73e-01 9.77e-02 8.44e-01
GO:0043197 dendritic spine 45 2.58e-01 -9.75e-02 7.31e-01
GO:0007596 blood coagulation 26 3.90e-01 9.74e-02 7.95e-01
GO:0000242 pericentriolar material 14 5.29e-01 9.73e-02 8.71e-01
GO:0051865 protein autoubiquitination 38 3.00e-01 9.73e-02 7.47e-01
GO:0035556 intracellular signal transduction 184 2.34e-02 9.71e-02 3.45e-01
GO:0060045 positive regulation of cardiac muscle cell proliferation 13 5.45e-01 -9.71e-02 8.76e-01
GO:0005758 mitochondrial intermembrane space 47 2.50e-01 -9.71e-02 7.28e-01
GO:1990782 protein tyrosine kinase binding 15 5.16e-01 9.69e-02 8.65e-01
GO:0048511 rhythmic process 25 4.02e-01 9.69e-02 7.97e-01
GO:0032731 positive regulation of interleukin-1 beta production 12 5.61e-01 -9.68e-02 8.78e-01
GO:0004519 endonuclease activity 14 5.31e-01 -9.67e-02 8.71e-01
GO:0045722 positive regulation of gluconeogenesis 11 5.79e-01 -9.66e-02 8.85e-01
GO:0090307 mitotic spindle assembly 30 3.60e-01 -9.66e-02 7.85e-01
GO:0000421 autophagosome membrane 24 4.15e-01 9.62e-02 8.04e-01
GO:0042273 ribosomal large subunit biogenesis 22 4.36e-01 -9.60e-02 8.22e-01
GO:0010595 positive regulation of endothelial cell migration 26 3.97e-01 9.60e-02 7.96e-01
GO:0007099 centriole replication 13 5.50e-01 -9.57e-02 8.77e-01
GO:0051489 regulation of filopodium assembly 10 6.00e-01 9.57e-02 8.96e-01
GO:0045814 negative regulation of gene expression, epigenetic 16 5.08e-01 -9.56e-02 8.62e-01
GO:0007626 locomotory behavior 28 3.82e-01 -9.55e-02 7.90e-01
GO:0016491 oxidoreductase activity 47 2.58e-01 -9.54e-02 7.31e-01
GO:0051402 neuron apoptotic process 42 2.86e-01 9.52e-02 7.44e-01
GO:0120020 cholesterol transfer activity 12 5.68e-01 -9.51e-02 8.81e-01
GO:0032040 small-subunit processome 59 2.07e-01 -9.51e-02 6.96e-01
GO:0005847 mRNA cleavage and polyadenylation specificity factor complex 11 5.85e-01 -9.50e-02 8.90e-01
GO:0004181 metallocarboxypeptidase activity 12 5.69e-01 -9.50e-02 8.81e-01
GO:0032259 methylation 76 1.53e-01 9.48e-02 6.62e-01
GO:1903078 positive regulation of protein localization to plasma membrane 21 4.53e-01 9.47e-02 8.29e-01
GO:0050852 T cell receptor signaling pathway 50 2.47e-01 -9.47e-02 7.25e-01
GO:0008180 COP9 signalosome 21 4.53e-01 -9.46e-02 8.29e-01
GO:0005178 integrin binding 65 1.88e-01 9.46e-02 6.90e-01
GO:0010608 post-transcriptional regulation of gene expression 11 5.87e-01 -9.45e-02 8.90e-01
GO:0006006 glucose metabolic process 26 4.04e-01 -9.45e-02 7.97e-01
GO:0090128 regulation of synapse maturation 10 6.06e-01 -9.43e-02 8.98e-01
GO:0051117 ATPase binding 44 2.81e-01 -9.40e-02 7.44e-01
GO:0042127 regulation of cell population proliferation 45 2.76e-01 -9.39e-02 7.39e-01
GO:0004252 serine-type endopeptidase activity 50 2.53e-01 -9.35e-02 7.28e-01
GO:0045453 bone resorption 11 5.92e-01 -9.33e-02 8.90e-01
GO:0035904 aorta development 15 5.32e-01 9.32e-02 8.72e-01
GO:1990247 N6-methyladenosine-containing RNA reader activity 10 6.10e-01 9.30e-02 8.99e-01
GO:0017018 myosin phosphatase activity 13 5.62e-01 9.30e-02 8.78e-01
GO:0140791 histone H2AXS140 phosphatase activity 13 5.62e-01 9.30e-02 8.78e-01
GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 13 5.62e-01 9.30e-02 8.78e-01
GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 13 5.62e-01 9.30e-02 8.78e-01
GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 13 5.62e-01 9.30e-02 8.78e-01
GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 13 5.62e-01 9.30e-02 8.78e-01
GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 13 5.62e-01 9.30e-02 8.78e-01
GO:1990439 MAP kinase serine/threonine phosphatase activity 13 5.62e-01 9.30e-02 8.78e-01
GO:0045672 positive regulation of osteoclast differentiation 11 5.93e-01 9.30e-02 8.90e-01
GO:0015030 Cajal body 26 4.14e-01 -9.26e-02 8.04e-01
GO:0055088 lipid homeostasis 18 4.99e-01 9.21e-02 8.61e-01
GO:0006509 membrane protein ectodomain proteolysis 15 5.38e-01 9.19e-02 8.73e-01
GO:0004693 cyclin-dependent protein serine/threonine kinase activity 10 6.15e-01 9.19e-02 9.00e-01
GO:0007283 spermatogenesis 100 1.13e-01 -9.18e-02 6.06e-01
GO:0031623 receptor internalization 21 4.67e-01 9.18e-02 8.39e-01
GO:0030027 lamellipodium 91 1.31e-01 9.17e-02 6.41e-01
GO:0043687 post-translational protein modification 19 4.89e-01 -9.17e-02 8.54e-01
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway 43 2.99e-01 9.16e-02 7.47e-01
GO:0005930 axoneme 48 2.76e-01 9.08e-02 7.39e-01
GO:0005925 focal adhesion 113 9.75e-02 9.04e-02 5.95e-01
GO:0030057 desmosome 11 6.04e-01 9.03e-02 8.98e-01
GO:0030145 manganese ion binding 45 2.95e-01 -9.03e-02 7.47e-01
GO:0010494 cytoplasmic stress granule 58 2.35e-01 9.03e-02 7.13e-01
GO:0071320 cellular response to cAMP 18 5.07e-01 -9.03e-02 8.62e-01
GO:0038202 TORC1 signaling 12 5.89e-01 9.02e-02 8.90e-01
GO:0007613 memory 28 4.09e-01 9.01e-02 8.02e-01
GO:0097194 execution phase of apoptosis 10 6.22e-01 9.00e-02 9.04e-01
GO:0031267 small GTPase binding 164 4.72e-02 9.00e-02 4.35e-01
GO:0030674 protein-macromolecule adaptor activity 73 1.84e-01 -9.00e-02 6.90e-01
GO:0035176 social behavior 17 5.22e-01 -8.96e-02 8.68e-01
GO:0009267 cellular response to starvation 49 2.79e-01 8.95e-02 7.40e-01
GO:0006368 transcription elongation by RNA polymerase II 24 4.49e-01 -8.94e-02 8.28e-01
GO:0030206 chondroitin sulfate biosynthetic process 11 6.09e-01 8.91e-02 8.98e-01
GO:0070050 neuron cellular homeostasis 14 5.65e-01 8.88e-02 8.79e-01
GO:2001222 regulation of neuron migration 10 6.27e-01 8.87e-02 9.04e-01
GO:0008266 poly(U) RNA binding 16 5.41e-01 -8.83e-02 8.74e-01
GO:0047496 vesicle transport along microtubule 11 6.13e-01 8.81e-02 9.00e-01
GO:0097110 scaffold protein binding 27 4.29e-01 -8.80e-02 8.16e-01
GO:0030140 trans-Golgi network transport vesicle 11 6.13e-01 8.80e-02 9.00e-01
GO:1990244 histone H2AT120 kinase activity 31 3.97e-01 8.79e-02 7.96e-01
GO:0005525 GTP binding 213 2.74e-02 -8.79e-02 3.59e-01
GO:0051016 barbed-end actin filament capping 15 5.56e-01 8.78e-02 8.78e-01
GO:0003924 GTPase activity 177 4.50e-02 -8.75e-02 4.31e-01
GO:0030665 clathrin-coated vesicle membrane 11 6.16e-01 -8.74e-02 9.00e-01
GO:0030199 collagen fibril organization 30 4.08e-01 8.74e-02 8.00e-01
GO:0006486 protein glycosylation 44 3.17e-01 -8.72e-02 7.59e-01
GO:0035403 histone H3T6 kinase activity 32 3.94e-01 8.71e-02 7.96e-01
GO:0005802 trans-Golgi network 99 1.35e-01 8.71e-02 6.47e-01
GO:0004672 protein kinase activity 64 2.29e-01 8.69e-02 7.13e-01
GO:0016607 nuclear speck 240 2.13e-02 -8.65e-02 3.38e-01
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 12 6.05e-01 8.62e-02 8.98e-01
GO:0031297 replication fork processing 26 4.47e-01 -8.62e-02 8.27e-01
GO:0046907 intracellular transport 14 5.77e-01 -8.61e-02 8.85e-01
GO:0030183 B cell differentiation 27 4.39e-01 -8.61e-02 8.23e-01
GO:0030500 regulation of bone mineralization 12 6.06e-01 8.59e-02 8.98e-01
GO:0043536 positive regulation of blood vessel endothelial cell migration 18 5.28e-01 -8.59e-02 8.71e-01
GO:0009966 regulation of signal transduction 37 3.67e-01 8.57e-02 7.88e-01
GO:0008285 negative regulation of cell population proliferation 115 1.13e-01 -8.57e-02 6.06e-01
GO:0017148 negative regulation of translation 43 3.31e-01 8.57e-02 7.71e-01
GO:0008201 heparin binding 56 2.68e-01 8.56e-02 7.32e-01
GO:0000166 nucleotide binding 36 3.75e-01 8.55e-02 7.90e-01
GO:0050673 epithelial cell proliferation 19 5.19e-01 8.54e-02 8.65e-01
GO:0051289 protein homotetramerization 34 3.89e-01 8.54e-02 7.95e-01
GO:0005783 endoplasmic reticulum 429 2.56e-03 -8.54e-02 1.35e-01
GO:0098839 postsynaptic density membrane 34 3.89e-01 8.53e-02 7.95e-01
GO:1904115 axon cytoplasm 25 4.61e-01 -8.53e-02 8.35e-01
GO:0051225 spindle assembly 21 4.99e-01 -8.53e-02 8.61e-01
GO:0006446 regulation of translational initiation 17 5.43e-01 -8.52e-02 8.75e-01
GO:0045177 apical part of cell 35 3.83e-01 8.52e-02 7.90e-01
GO:0051018 protein kinase A binding 12 6.10e-01 8.51e-02 8.98e-01
GO:0008408 3’-5’ exonuclease activity 10 6.41e-01 8.51e-02 9.11e-01
GO:0030127 COPII vesicle coat 10 6.41e-01 8.51e-02 9.11e-01
GO:0008045 motor neuron axon guidance 11 6.27e-01 8.47e-02 9.04e-01
GO:0005741 mitochondrial outer membrane 95 1.56e-01 -8.44e-02 6.62e-01
GO:0016853 isomerase activity 19 5.26e-01 8.41e-02 8.70e-01
GO:0008033 tRNA processing 15 5.73e-01 -8.40e-02 8.83e-01
GO:0009306 protein secretion 20 5.17e-01 -8.37e-02 8.65e-01
GO:0050772 positive regulation of axonogenesis 12 6.16e-01 8.36e-02 9.00e-01
GO:0001541 ovarian follicle development 19 5.30e-01 -8.33e-02 8.71e-01
GO:0016328 lateral plasma membrane 24 4.80e-01 8.33e-02 8.50e-01
GO:0010506 regulation of autophagy 26 4.63e-01 8.32e-02 8.38e-01
GO:0007129 homologous chromosome pairing at meiosis 13 6.04e-01 -8.32e-02 8.98e-01
GO:0070507 regulation of microtubule cytoskeleton organization 14 5.90e-01 -8.32e-02 8.90e-01
GO:0005245 voltage-gated calcium channel activity 11 6.34e-01 -8.30e-02 9.08e-01
GO:0032722 positive regulation of chemokine production 11 6.34e-01 -8.30e-02 9.08e-01
GO:0043995 histone H4K5 acetyltransferase activity 10 6.50e-01 8.28e-02 9.14e-01
GO:0043996 histone H4K8 acetyltransferase activity 10 6.50e-01 8.28e-02 9.14e-01
GO:0048477 oogenesis 14 5.92e-01 -8.27e-02 8.90e-01
GO:0007507 heart development 78 2.07e-01 8.27e-02 6.96e-01
GO:0031463 Cul3-RING ubiquitin ligase complex 41 3.60e-01 8.27e-02 7.85e-01
GO:0032456 endocytic recycling 42 3.57e-01 -8.22e-02 7.82e-01
GO:0050890 cognition 18 5.46e-01 8.21e-02 8.76e-01
GO:0019221 cytokine-mediated signaling pathway 45 3.41e-01 -8.21e-02 7.75e-01
GO:0035869 ciliary transition zone 22 5.06e-01 8.18e-02 8.62e-01
GO:0032728 positive regulation of interferon-beta production 15 5.84e-01 8.17e-02 8.88e-01
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 18 5.50e-01 8.15e-02 8.77e-01
GO:0005763 mitochondrial small ribosomal subunit 21 5.18e-01 -8.15e-02 8.65e-01
GO:0016192 vesicle-mediated transport 101 1.59e-01 -8.12e-02 6.62e-01
GO:0045931 positive regulation of mitotic cell cycle 14 5.99e-01 8.12e-02 8.95e-01
GO:0005515 protein binding 90 1.86e-01 8.07e-02 6.90e-01
GO:0097602 cullin family protein binding 16 5.77e-01 -8.05e-02 8.85e-01
GO:0030010 establishment of cell polarity 18 5.56e-01 8.02e-02 8.78e-01
GO:0006914 autophagy 43 3.63e-01 -8.01e-02 7.88e-01
GO:0016787 hydrolase activity 107 1.53e-01 8.00e-02 6.62e-01
GO:0007097 nuclear migration 15 5.92e-01 -7.99e-02 8.90e-01
GO:0035145 exon-exon junction complex 10 6.62e-01 -7.99e-02 9.17e-01
GO:0070536 protein K63-linked deubiquitination 16 5.80e-01 7.99e-02 8.85e-01
GO:0008284 positive regulation of cell population proliferation 157 8.50e-02 -7.98e-02 5.86e-01
GO:0045665 negative regulation of neuron differentiation 24 5.00e-01 7.96e-02 8.61e-01
GO:0045666 positive regulation of neuron differentiation 26 4.83e-01 -7.96e-02 8.50e-01
GO:0120163 negative regulation of cold-induced thermogenesis 21 5.28e-01 7.95e-02 8.71e-01
GO:0006986 response to unfolded protein 12 6.34e-01 7.94e-02 9.08e-01
GO:0043204 perikaryon 35 4.18e-01 -7.92e-02 8.04e-01
GO:0048813 dendrite morphogenesis 21 5.30e-01 7.91e-02 8.71e-01
GO:0050821 protein stabilization 109 1.58e-01 -7.85e-02 6.62e-01
GO:0016604 nuclear body 173 7.56e-02 7.85e-02 5.62e-01
GO:0000774 adenyl-nucleotide exchange factor activity 12 6.38e-01 7.84e-02 9.11e-01
GO:0007517 muscle organ development 11 6.53e-01 7.82e-02 9.14e-01
GO:0030659 cytoplasmic vesicle membrane 43 3.75e-01 7.82e-02 7.90e-01
GO:0001558 regulation of cell growth 24 5.08e-01 -7.81e-02 8.62e-01
GO:0051015 actin filament binding 116 1.48e-01 7.80e-02 6.62e-01
GO:0048705 skeletal system morphogenesis 14 6.14e-01 7.78e-02 9.00e-01
GO:0030136 clathrin-coated vesicle 29 4.69e-01 -7.78e-02 8.40e-01
GO:0071407 cellular response to organic cyclic compound 11 6.56e-01 7.76e-02 9.16e-01
GO:0005795 Golgi stack 18 5.69e-01 7.76e-02 8.81e-01
GO:0036297 interstrand cross-link repair 24 5.11e-01 -7.75e-02 8.63e-01
GO:0005254 chloride channel activity 19 5.60e-01 -7.74e-02 8.78e-01
GO:0006400 tRNA modification 12 6.43e-01 -7.73e-02 9.11e-01
GO:0042393 histone binding 95 1.94e-01 7.73e-02 6.92e-01
GO:0090090 negative regulation of canonical Wnt signaling pathway 70 2.64e-01 7.72e-02 7.32e-01
GO:0051649 establishment of localization in cell 37 4.18e-01 -7.70e-02 8.04e-01
GO:0007249 canonical NF-kappaB signal transduction 18 5.73e-01 -7.68e-02 8.83e-01
GO:0043066 negative regulation of apoptotic process 152 1.03e-01 -7.67e-02 5.96e-01
GO:0099560 synaptic membrane adhesion 14 6.20e-01 7.67e-02 9.03e-01
GO:0045766 positive regulation of angiogenesis 53 3.36e-01 -7.65e-02 7.72e-01
GO:0050679 positive regulation of epithelial cell proliferation 20 5.54e-01 -7.64e-02 8.78e-01
GO:0043296 apical junction complex 10 6.76e-01 7.64e-02 9.25e-01
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 12 6.48e-01 -7.60e-02 9.13e-01
GO:0031124 mRNA 3’-end processing 13 6.35e-01 -7.60e-02 9.08e-01
GO:0006879 intracellular iron ion homeostasis 31 4.65e-01 -7.59e-02 8.38e-01
GO:0006094 gluconeogenesis 20 5.59e-01 -7.56e-02 8.78e-01
GO:0016581 NuRD complex 10 6.81e-01 -7.52e-02 9.25e-01
GO:0001889 liver development 30 4.78e-01 -7.49e-02 8.50e-01
GO:0017022 myosin binding 11 6.68e-01 7.47e-02 9.19e-01
GO:0001046 core promoter sequence-specific DNA binding 11 6.68e-01 -7.47e-02 9.19e-01
GO:0042470 melanosome 27 5.03e-01 -7.45e-02 8.61e-01
GO:0006887 exocytosis 42 4.04e-01 -7.44e-02 7.97e-01
GO:0051260 protein homooligomerization 48 3.73e-01 -7.43e-02 7.90e-01
GO:0051604 protein maturation 20 5.65e-01 7.43e-02 8.79e-01
GO:0006413 translational initiation 30 4.82e-01 -7.42e-02 8.50e-01
GO:0004711 ribosomal protein S6 kinase activity 32 4.68e-01 7.41e-02 8.40e-01
GO:0001676 long-chain fatty acid metabolic process 11 6.70e-01 -7.41e-02 9.21e-01
GO:0044877 protein-containing complex binding 104 1.93e-01 7.40e-02 6.92e-01
GO:0008593 regulation of Notch signaling pathway 10 6.87e-01 -7.36e-02 9.28e-01
GO:1905515 non-motile cilium assembly 39 4.28e-01 -7.34e-02 8.16e-01
GO:0005911 cell-cell junction 77 2.67e-01 7.32e-02 7.32e-01
GO:0031573 mitotic intra-S DNA damage checkpoint signaling 11 6.75e-01 -7.31e-02 9.25e-01
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 12 6.62e-01 7.29e-02 9.17e-01
GO:0043022 ribosome binding 46 3.94e-01 7.27e-02 7.96e-01
GO:0051496 positive regulation of stress fiber assembly 31 4.84e-01 7.27e-02 8.50e-01
GO:0005814 centriole 91 2.31e-01 -7.27e-02 7.13e-01
GO:0060261 positive regulation of transcription initiation by RNA polymerase II 30 4.92e-01 7.25e-02 8.58e-01
GO:1903076 regulation of protein localization to plasma membrane 18 5.96e-01 7.23e-02 8.92e-01
GO:0006635 fatty acid beta-oxidation 26 5.24e-01 7.21e-02 8.70e-01
GO:0045087 innate immune response 80 2.68e-01 -7.17e-02 7.32e-01
GO:0006508 proteolysis 170 1.08e-01 -7.17e-02 5.96e-01
GO:0006979 response to oxidative stress 50 3.82e-01 7.16e-02 7.90e-01
GO:0005811 lipid droplet 42 4.25e-01 -7.12e-02 8.15e-01
GO:0090110 COPII-coated vesicle cargo loading 10 6.97e-01 -7.11e-02 9.30e-01
GO:0061744 motor behavior 16 6.25e-01 -7.07e-02 9.04e-01
GO:0061462 protein localization to lysosome 10 7.00e-01 7.04e-02 9.32e-01
GO:0030332 cyclin binding 20 5.86e-01 -7.04e-02 8.90e-01
GO:0006909 phagocytosis 22 5.69e-01 -7.02e-02 8.81e-01
GO:1990830 cellular response to leukemia inhibitory factor 66 3.24e-01 7.02e-02 7.64e-01
GO:0042327 positive regulation of phosphorylation 13 6.61e-01 7.02e-02 9.17e-01
GO:0019894 kinesin binding 21 5.80e-01 6.99e-02 8.85e-01
GO:2000786 positive regulation of autophagosome assembly 14 6.51e-01 -6.98e-02 9.14e-01
GO:0030488 tRNA methylation 20 5.89e-01 6.98e-02 8.90e-01
GO:0097546 ciliary base 17 6.20e-01 -6.95e-02 9.03e-01
GO:0043495 protein-membrane adaptor activity 17 6.20e-01 6.95e-02 9.03e-01
GO:0098655 monoatomic cation transmembrane transport 14 6.53e-01 6.93e-02 9.14e-01
GO:0042802 identical protein binding 658 2.68e-03 -6.92e-02 1.35e-01
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway 11 6.91e-01 -6.91e-02 9.29e-01
GO:0016791 phosphatase activity 15 6.43e-01 6.91e-02 9.11e-01
GO:0043231 intracellular membrane-bounded organelle 115 2.03e-01 -6.89e-02 6.96e-01
GO:0007519 skeletal muscle tissue development 17 6.23e-01 -6.89e-02 9.04e-01
GO:0003774 cytoskeletal motor activity 12 6.81e-01 6.86e-02 9.25e-01
GO:0061484 hematopoietic stem cell homeostasis 12 6.83e-01 6.82e-02 9.26e-01
GO:0060021 roof of mouth development 36 4.80e-01 -6.80e-02 8.50e-01
GO:0030501 positive regulation of bone mineralization 14 6.60e-01 -6.78e-02 9.17e-01
GO:0030295 protein kinase activator activity 21 5.93e-01 6.73e-02 8.90e-01
GO:0032755 positive regulation of interleukin-6 production 32 5.12e-01 6.70e-02 8.63e-01
GO:0071108 protein K48-linked deubiquitination 15 6.53e-01 -6.70e-02 9.14e-01
GO:0005768 endosome 114 2.17e-01 -6.70e-02 6.97e-01
GO:0022604 regulation of cell morphogenesis 14 6.65e-01 6.69e-02 9.18e-01
GO:0006874 intracellular calcium ion homeostasis 36 4.88e-01 -6.69e-02 8.53e-01
GO:0014069 postsynaptic density 99 2.51e-01 6.69e-02 7.28e-01
GO:0000793 condensed chromosome 13 6.78e-01 -6.66e-02 9.25e-01
GO:0010467 gene expression 79 3.08e-01 6.64e-02 7.48e-01
GO:0051059 NF-kappaB binding 22 5.91e-01 -6.62e-02 8.90e-01
GO:0004535 poly(A)-specific ribonuclease activity 10 7.17e-01 -6.61e-02 9.39e-01
GO:0035198 miRNA binding 20 6.09e-01 6.61e-02 8.98e-01
GO:0006298 mismatch repair 16 6.48e-01 6.60e-02 9.13e-01
GO:0030593 neutrophil chemotaxis 13 6.81e-01 6.59e-02 9.25e-01
GO:0061025 membrane fusion 21 6.02e-01 -6.57e-02 8.98e-01
GO:0034113 heterotypic cell-cell adhesion 12 6.94e-01 -6.57e-02 9.30e-01
GO:0008320 protein transmembrane transporter activity 11 7.07e-01 -6.55e-02 9.36e-01
GO:0005978 glycogen biosynthetic process 11 7.08e-01 -6.53e-02 9.36e-01
GO:0060382 regulation of DNA strand elongation 10 7.23e-01 -6.48e-02 9.39e-01
GO:0003712 transcription coregulator activity 75 3.33e-01 6.47e-02 7.72e-01
GO:0030374 nuclear receptor coactivator activity 30 5.40e-01 -6.46e-02 8.74e-01
GO:2000811 negative regulation of anoikis 10 7.23e-01 -6.46e-02 9.39e-01
GO:0000902 cell morphogenesis 54 4.16e-01 6.40e-02 8.04e-01
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 21 6.12e-01 -6.39e-02 9.00e-01
GO:0035567 non-canonical Wnt signaling pathway 13 6.90e-01 -6.39e-02 9.28e-01
GO:0071353 cellular response to interleukin-4 10 7.27e-01 6.37e-02 9.39e-01
GO:0030866 cortical actin cytoskeleton organization 20 6.23e-01 6.36e-02 9.04e-01
GO:0042130 negative regulation of T cell proliferation 12 7.03e-01 -6.35e-02 9.34e-01
GO:0007409 axonogenesis 40 4.88e-01 6.35e-02 8.53e-01
GO:0033192 calmodulin-dependent protein phosphatase activity 16 6.61e-01 6.34e-02 9.17e-01
GO:0019903 protein phosphatase binding 49 4.43e-01 6.33e-02 8.24e-01
GO:0032720 negative regulation of tumor necrosis factor production 18 6.43e-01 -6.32e-02 9.11e-01
GO:0010977 negative regulation of neuron projection development 16 6.62e-01 -6.32e-02 9.17e-01
GO:0035019 somatic stem cell population maintenance 31 5.44e-01 -6.31e-02 8.76e-01
GO:0004860 protein kinase inhibitor activity 19 6.35e-01 -6.30e-02 9.08e-01
GO:0106310 protein serine kinase activity 38 5.02e-01 -6.29e-02 8.61e-01
GO:0010975 regulation of neuron projection development 16 6.63e-01 -6.29e-02 9.17e-01
GO:0003925 G protein activity 18 6.45e-01 -6.28e-02 9.11e-01
GO:0070034 telomerase RNA binding 12 7.06e-01 6.28e-02 9.36e-01
GO:0005902 microvillus 27 5.73e-01 -6.28e-02 8.83e-01
GO:0035091 phosphatidylinositol binding 74 3.52e-01 6.26e-02 7.80e-01
GO:0007266 Rho protein signal transduction 33 5.34e-01 6.25e-02 8.72e-01
GO:0022857 transmembrane transporter activity 38 5.05e-01 6.25e-02 8.62e-01
GO:0003724 RNA helicase activity 37 5.11e-01 6.24e-02 8.63e-01
GO:0099149 regulation of postsynaptic neurotransmitter receptor internalization 12 7.08e-01 -6.23e-02 9.36e-01
GO:0098794 postsynapse 66 3.82e-01 6.23e-02 7.90e-01
GO:0030426 growth cone 42 4.85e-01 -6.23e-02 8.50e-01
GO:0045746 negative regulation of Notch signaling pathway 15 6.76e-01 -6.23e-02 9.25e-01
GO:0043409 negative regulation of MAPK cascade 20 6.30e-01 -6.22e-02 9.06e-01
GO:0032391 photoreceptor connecting cilium 18 6.49e-01 -6.21e-02 9.13e-01
GO:0005200 structural constituent of cytoskeleton 27 5.78e-01 6.19e-02 8.85e-01
GO:0017134 fibroblast growth factor binding 12 7.10e-01 6.19e-02 9.38e-01
GO:0034045 phagophore assembly site membrane 12 7.11e-01 -6.19e-02 9.38e-01
GO:0007264 small GTPase-mediated signal transduction 47 4.63e-01 6.18e-02 8.38e-01
GO:0043123 positive regulation of canonical NF-kappaB signal transduction 76 3.54e-01 -6.16e-02 7.81e-01
GO:0070840 dynein complex binding 11 7.24e-01 6.15e-02 9.39e-01
GO:0042254 ribosome biogenesis 16 6.73e-01 6.10e-02 9.23e-01
GO:0045724 positive regulation of cilium assembly 13 7.04e-01 6.09e-02 9.34e-01
GO:0007288 sperm axoneme assembly 17 6.64e-01 -6.09e-02 9.17e-01
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading 24 6.06e-01 6.09e-02 8.98e-01
GO:0016055 Wnt signaling pathway 77 3.57e-01 6.08e-02 7.82e-01
GO:0019901 protein kinase binding 237 1.08e-01 -6.07e-02 5.96e-01
GO:0048787 presynaptic active zone membrane 10 7.40e-01 -6.06e-02 9.40e-01
GO:0035591 signaling adaptor activity 40 5.08e-01 6.05e-02 8.62e-01
GO:0003723 RNA binding 372 4.63e-02 -6.04e-02 4.33e-01
GO:0004197 cysteine-type endopeptidase activity 36 5.34e-01 -5.99e-02 8.72e-01
GO:0042995 cell projection 53 4.51e-01 5.99e-02 8.29e-01
GO:0055085 transmembrane transport 84 3.45e-01 5.97e-02 7.78e-01
GO:0030216 keratinocyte differentiation 27 5.92e-01 -5.96e-02 8.90e-01
GO:0033962 P-body assembly 14 7.01e-01 5.93e-02 9.33e-01
GO:0031201 SNARE complex 33 5.57e-01 -5.91e-02 8.78e-01
GO:0004435 phosphatidylinositol phospholipase C activity 12 7.23e-01 -5.91e-02 9.39e-01
GO:0007160 cell-matrix adhesion 40 5.19e-01 -5.90e-02 8.65e-01
GO:0000287 magnesium ion binding 149 2.15e-01 -5.89e-02 6.96e-01
GO:0001570 vasculogenesis 26 6.04e-01 -5.87e-02 8.98e-01
GO:0008092 cytoskeletal protein binding 15 6.94e-01 -5.86e-02 9.30e-01
GO:0071222 cellular response to lipopolysaccharide 45 4.97e-01 -5.86e-02 8.61e-01
GO:0016592 mediator complex 28 5.93e-01 5.84e-02 8.90e-01
GO:1900181 negative regulation of protein localization to nucleus 11 7.38e-01 -5.84e-02 9.40e-01
GO:0015031 protein transport 173 1.87e-01 -5.83e-02 6.90e-01
GO:0009617 response to bacterium 35 5.51e-01 5.82e-02 8.77e-01
GO:0004177 aminopeptidase activity 12 7.27e-01 -5.82e-02 9.39e-01
GO:0007605 sensory perception of sound 53 4.64e-01 -5.81e-02 8.38e-01
GO:0044782 cilium organization 13 7.17e-01 5.81e-02 9.39e-01
GO:0005929 cilium 78 3.76e-01 -5.81e-02 7.90e-01
GO:0060379 cardiac muscle cell myoblast differentiation 10 7.51e-01 5.79e-02 9.41e-01
GO:0016042 lipid catabolic process 29 5.90e-01 5.79e-02 8.90e-01
GO:0032465 regulation of cytokinesis 23 6.32e-01 5.78e-02 9.08e-01
GO:0010212 response to ionizing radiation 24 6.25e-01 5.77e-02 9.04e-01
GO:0060349 bone morphogenesis 12 7.29e-01 5.77e-02 9.39e-01
GO:0042169 SH2 domain binding 20 6.55e-01 5.77e-02 9.15e-01
GO:0016973 poly(A)+ mRNA export from nucleus 13 7.19e-01 -5.77e-02 9.39e-01
GO:0004857 enzyme inhibitor activity 12 7.30e-01 5.76e-02 9.39e-01
GO:0031594 neuromuscular junction 34 5.61e-01 5.76e-02 8.78e-01
GO:0045669 positive regulation of osteoblast differentiation 37 5.50e-01 5.69e-02 8.77e-01
GO:0007186 G protein-coupled receptor signaling pathway 91 3.51e-01 5.67e-02 7.80e-01
GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 34 5.69e-01 5.65e-02 8.81e-01
GO:0035924 cellular response to vascular endothelial growth factor stimulus 16 6.97e-01 -5.63e-02 9.30e-01
GO:0060218 hematopoietic stem cell differentiation 11 7.47e-01 5.61e-02 9.40e-01
GO:0032874 positive regulation of stress-activated MAPK cascade 11 7.48e-01 -5.60e-02 9.40e-01
GO:0018279 protein N-linked glycosylation via asparagine 11 7.48e-01 -5.60e-02 9.40e-01
GO:0043539 protein serine/threonine kinase activator activity 34 5.73e-01 -5.59e-02 8.83e-01
GO:0016477 cell migration 134 2.66e-01 5.58e-02 7.32e-01
GO:0043616 keratinocyte proliferation 11 7.50e-01 -5.56e-02 9.40e-01
GO:0030324 lung development 35 5.70e-01 -5.55e-02 8.81e-01
GO:2000377 regulation of reactive oxygen species metabolic process 10 7.62e-01 5.54e-02 9.46e-01
GO:0005819 spindle 54 4.82e-01 5.54e-02 8.50e-01
GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site 16 7.02e-01 5.52e-02 9.34e-01
GO:0031490 chromatin DNA binding 40 5.47e-01 5.51e-02 8.76e-01
GO:0042789 mRNA transcription by RNA polymerase II 27 6.21e-01 5.50e-02 9.03e-01
GO:0021915 neural tube development 15 7.13e-01 -5.50e-02 9.39e-01
GO:0001221 transcription coregulator binding 17 6.96e-01 -5.47e-02 9.30e-01
GO:0050729 positive regulation of inflammatory response 22 6.58e-01 -5.45e-02 9.17e-01
GO:0030198 extracellular matrix organization 75 4.15e-01 5.45e-02 8.04e-01
GO:0140374 antiviral innate immune response 20 6.73e-01 -5.45e-02 9.23e-01
GO:0048821 erythrocyte development 15 7.15e-01 -5.44e-02 9.39e-01
GO:0071711 basement membrane organization 11 7.55e-01 5.43e-02 9.42e-01
GO:0031982 vesicle 27 6.26e-01 -5.42e-02 9.04e-01
GO:0035987 endodermal cell differentiation 22 6.60e-01 5.41e-02 9.17e-01
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane 18 6.92e-01 -5.40e-02 9.29e-01
GO:0045765 regulation of angiogenesis 11 7.57e-01 -5.40e-02 9.42e-01
GO:0000932 P-body 60 4.71e-01 -5.38e-02 8.42e-01
GO:0042826 histone deacetylase binding 66 4.50e-01 -5.38e-02 8.29e-01
GO:0001673 male germ cell nucleus 27 6.30e-01 5.36e-02 9.06e-01
GO:0030017 sarcomere 13 7.39e-01 -5.34e-02 9.40e-01
GO:0003725 double-stranded RNA binding 44 5.41e-01 5.32e-02 8.74e-01
GO:0001662 behavioral fear response 12 7.50e-01 5.32e-02 9.40e-01
GO:0030878 thyroid gland development 14 7.31e-01 -5.32e-02 9.39e-01
GO:0055038 recycling endosome membrane 43 5.47e-01 -5.31e-02 8.76e-01
GO:0005730 nucleolus 441 5.78e-02 -5.30e-02 4.87e-01
GO:0000165 MAPK cascade 46 5.36e-01 -5.28e-02 8.72e-01
GO:0043130 ubiquitin binding 62 4.73e-01 -5.27e-02 8.44e-01
GO:0004683 calcium/calmodulin-dependent protein kinase activity 11 7.63e-01 -5.25e-02 9.46e-01
GO:0045739 positive regulation of DNA repair 20 6.85e-01 5.24e-02 9.27e-01
GO:0051321 meiotic cell cycle 21 6.78e-01 -5.23e-02 9.25e-01
GO:0070098 chemokine-mediated signaling pathway 10 7.75e-01 -5.22e-02 9.47e-01
GO:0008089 anterograde axonal transport 10 7.75e-01 5.21e-02 9.47e-01
GO:0003785 actin monomer binding 13 7.46e-01 -5.20e-02 9.40e-01
GO:0002244 hematopoietic progenitor cell differentiation 35 5.98e-01 5.15e-02 8.95e-01
GO:0071364 cellular response to epidermal growth factor stimulus 19 6.98e-01 5.14e-02 9.31e-01
GO:0072089 stem cell proliferation 21 6.84e-01 -5.14e-02 9.27e-01
GO:0007179 transforming growth factor beta receptor signaling pathway 48 5.38e-01 -5.14e-02 8.73e-01
GO:0016446 somatic hypermutation of immunoglobulin genes 10 7.79e-01 5.12e-02 9.47e-01
GO:0005249 voltage-gated potassium channel activity 13 7.49e-01 -5.12e-02 9.40e-01
GO:0035371 microtubule plus-end 12 7.59e-01 5.11e-02 9.44e-01
GO:0045892 negative regulation of DNA-templated transcription 174 2.46e-01 5.11e-02 7.22e-01
GO:0019955 cytokine binding 12 7.60e-01 -5.09e-02 9.45e-01
GO:0140664 ATP-dependent DNA damage sensor activity 14 7.42e-01 -5.08e-02 9.40e-01
GO:0090263 positive regulation of canonical Wnt signaling pathway 61 4.93e-01 5.08e-02 8.58e-01
GO:0007015 actin filament organization 71 4.60e-01 5.08e-02 8.34e-01
GO:0045740 positive regulation of DNA replication 11 7.71e-01 -5.08e-02 9.47e-01
GO:0036503 ERAD pathway 59 5.01e-01 5.07e-02 8.61e-01
GO:0099523 presynaptic cytosol 11 7.72e-01 5.04e-02 9.47e-01
GO:0042098 T cell proliferation 16 7.28e-01 5.02e-02 9.39e-01
GO:0030054 cell junction 53 5.28e-01 -5.02e-02 8.71e-01
GO:0097060 synaptic membrane 11 7.73e-01 5.01e-02 9.47e-01
GO:0097009 energy homeostasis 23 6.79e-01 4.99e-02 9.25e-01
GO:0071456 cellular response to hypoxia 34 6.16e-01 4.97e-02 9.00e-01
GO:0046961 proton-transporting ATPase activity, rotational mechanism 14 7.48e-01 -4.96e-02 9.40e-01
GO:0030331 nuclear estrogen receptor binding 19 7.08e-01 4.96e-02 9.36e-01
GO:0044331 cell-cell adhesion mediated by cadherin 11 7.76e-01 4.95e-02 9.47e-01
GO:0019904 protein domain specific binding 104 3.84e-01 -4.95e-02 7.90e-01
GO:0032206 positive regulation of telomere maintenance 14 7.49e-01 -4.94e-02 9.40e-01
GO:0031663 lipopolysaccharide-mediated signaling pathway 10 7.87e-01 4.94e-02 9.50e-01
GO:0005764 lysosome 130 3.32e-01 -4.93e-02 7.72e-01
GO:0055074 calcium ion homeostasis 17 7.26e-01 -4.91e-02 9.39e-01
GO:0001525 angiogenesis 86 4.34e-01 -4.89e-02 8.22e-01
GO:0006366 transcription by RNA polymerase II 73 4.72e-01 4.88e-02 8.42e-01
GO:0048026 positive regulation of mRNA splicing, via spliceosome 12 7.71e-01 -4.86e-02 9.47e-01
GO:0006629 lipid metabolic process 51 5.49e-01 -4.85e-02 8.77e-01
GO:0008168 methyltransferase activity 13 7.64e-01 4.81e-02 9.47e-01
GO:0001935 endothelial cell proliferation 12 7.73e-01 -4.80e-02 9.47e-01
GO:0045202 synapse 165 2.90e-01 -4.79e-02 7.47e-01
GO:1901981 phosphatidylinositol phosphate binding 16 7.41e-01 4.77e-02 9.40e-01
GO:0030177 positive regulation of Wnt signaling pathway 17 7.34e-01 -4.76e-02 9.40e-01
GO:0099170 postsynaptic modulation of chemical synaptic transmission 13 7.67e-01 4.75e-02 9.47e-01
GO:0010508 positive regulation of autophagy 39 6.10e-01 -4.73e-02 8.98e-01
GO:0043025 neuronal cell body 84 4.55e-01 -4.73e-02 8.29e-01
GO:0030316 osteoclast differentiation 28 6.65e-01 4.72e-02 9.18e-01
GO:0097718 disordered domain specific binding 15 7.52e-01 4.72e-02 9.41e-01
GO:0015630 microtubule cytoskeleton 70 5.00e-01 4.67e-02 8.61e-01
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 12 7.80e-01 -4.66e-02 9.47e-01
GO:0009611 response to wounding 18 7.32e-01 4.66e-02 9.40e-01
GO:0030218 erythrocyte differentiation 28 6.70e-01 4.66e-02 9.20e-01
GO:0010314 phosphatidylinositol-5-phosphate binding 10 7.99e-01 4.66e-02 9.55e-01
GO:0004888 transmembrane signaling receptor activity 23 6.99e-01 4.66e-02 9.32e-01
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway 13 7.71e-01 -4.66e-02 9.47e-01
GO:0010628 positive regulation of gene expression 146 3.33e-01 4.65e-02 7.72e-01
GO:0032729 positive regulation of type II interferon production 22 7.07e-01 -4.64e-02 9.36e-01
GO:0070527 platelet aggregation 16 7.48e-01 4.63e-02 9.40e-01
GO:0090314 positive regulation of protein targeting to membrane 12 7.81e-01 -4.63e-02 9.47e-01
GO:0045070 positive regulation of viral genome replication 19 7.27e-01 4.63e-02 9.39e-01
GO:0005198 structural molecule activity 37 6.27e-01 4.62e-02 9.04e-01
GO:0000226 microtubule cytoskeleton organization 68 5.12e-01 -4.60e-02 8.63e-01
GO:0001843 neural tube closure 48 5.82e-01 4.60e-02 8.86e-01
GO:0048010 vascular endothelial growth factor receptor signaling pathway 13 7.76e-01 -4.56e-02 9.47e-01
GO:0006954 inflammatory response 81 4.78e-01 -4.56e-02 8.50e-01
GO:0005794 Golgi apparatus 464 9.47e-02 -4.55e-02 5.95e-01
GO:0051879 Hsp90 protein binding 26 6.89e-01 4.53e-02 9.28e-01
GO:1904019 epithelial cell apoptotic process 13 7.77e-01 -4.53e-02 9.47e-01
GO:0051491 positive regulation of filopodium assembly 14 7.69e-01 4.53e-02 9.47e-01
GO:0051497 negative regulation of stress fiber assembly 18 7.40e-01 4.52e-02 9.40e-01
GO:0003148 outflow tract septum morphogenesis 12 7.87e-01 4.51e-02 9.50e-01
GO:0005096 GTPase activator activity 150 3.42e-01 4.51e-02 7.75e-01
GO:1904263 positive regulation of TORC1 signaling 35 6.45e-01 4.50e-02 9.12e-01
GO:0098586 cellular response to virus 22 7.15e-01 4.49e-02 9.39e-01
GO:0051123 RNA polymerase II preinitiation complex assembly 16 7.56e-01 -4.48e-02 9.42e-01
GO:0045599 negative regulation of fat cell differentiation 21 7.23e-01 4.47e-02 9.39e-01
GO:0006289 nucleotide-excision repair 22 7.18e-01 -4.45e-02 9.39e-01
GO:0050919 negative chemotaxis 19 7.37e-01 4.45e-02 9.40e-01
GO:0007265 Ras protein signal transduction 37 6.41e-01 4.43e-02 9.11e-01
GO:0005669 transcription factor TFIID complex 22 7.19e-01 -4.43e-02 9.39e-01
GO:0003690 double-stranded DNA binding 35 6.53e-01 -4.40e-02 9.14e-01
GO:0036158 outer dynein arm assembly 10 8.10e-01 -4.39e-02 9.61e-01
GO:0007005 mitochondrion organization 62 5.51e-01 -4.38e-02 8.77e-01
GO:0001650 fibrillar center 101 4.48e-01 -4.38e-02 8.27e-01
GO:0042803 protein homodimerization activity 371 1.50e-01 -4.37e-02 6.62e-01
GO:0009410 response to xenobiotic stimulus 46 6.08e-01 4.37e-02 8.98e-01
GO:0000976 transcription cis-regulatory region binding 54 5.80e-01 -4.36e-02 8.85e-01
GO:0035035 histone acetyltransferase binding 12 7.94e-01 -4.36e-02 9.54e-01
GO:0035064 methylated histone binding 42 6.27e-01 4.34e-02 9.04e-01
GO:0017124 SH3 domain binding 43 6.23e-01 4.33e-02 9.04e-01
GO:0060612 adipose tissue development 23 7.20e-01 -4.31e-02 9.39e-01
GO:0010629 negative regulation of gene expression 101 4.54e-01 4.31e-02 8.29e-01
GO:1990166 protein localization to site of double-strand break 10 8.14e-01 4.29e-02 9.61e-01
GO:0001750 photoreceptor outer segment 22 7.28e-01 4.29e-02 9.39e-01
GO:0016324 apical plasma membrane 120 4.18e-01 4.29e-02 8.04e-01
GO:0120162 positive regulation of cold-induced thermogenesis 30 6.86e-01 -4.27e-02 9.27e-01
GO:0030425 dendrite 133 3.96e-01 4.27e-02 7.96e-01
GO:0019216 regulation of lipid metabolic process 10 8.15e-01 -4.26e-02 9.61e-01
GO:0007420 brain development 77 5.18e-01 -4.26e-02 8.65e-01
GO:0008021 synaptic vesicle 47 6.13e-01 4.26e-02 9.00e-01
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 14 7.83e-01 -4.26e-02 9.47e-01
GO:0042383 sarcolemma 36 6.59e-01 4.25e-02 9.17e-01
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 84 5.02e-01 4.24e-02 8.61e-01
GO:0007219 Notch signaling pathway 41 6.39e-01 -4.24e-02 9.11e-01
GO:0006270 DNA replication initiation 19 7.50e-01 -4.23e-02 9.40e-01
GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process 14 7.84e-01 4.23e-02 9.48e-01
GO:0005774 vacuolar membrane 10 8.17e-01 -4.23e-02 9.61e-01
GO:0071356 cellular response to tumor necrosis factor 37 6.57e-01 4.22e-02 9.16e-01
GO:0007405 neuroblast proliferation 21 7.38e-01 -4.21e-02 9.40e-01
GO:0072659 protein localization to plasma membrane 75 5.29e-01 4.21e-02 8.71e-01
GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction 35 6.67e-01 -4.20e-02 9.19e-01
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 21 7.39e-01 4.20e-02 9.40e-01
GO:0001708 cell fate specification 12 8.02e-01 -4.19e-02 9.57e-01
GO:0000785 chromatin 242 2.64e-01 4.19e-02 7.32e-01
GO:0051965 positive regulation of synapse assembly 21 7.40e-01 4.18e-02 9.40e-01
GO:0001772 immunological synapse 23 7.29e-01 -4.18e-02 9.39e-01
GO:0005789 endoplasmic reticulum membrane 400 1.58e-01 -4.14e-02 6.62e-01
GO:0046580 negative regulation of Ras protein signal transduction 13 7.96e-01 -4.13e-02 9.55e-01
GO:0030154 cell differentiation 141 3.98e-01 -4.13e-02 7.96e-01
GO:0070588 calcium ion transmembrane transport 45 6.35e-01 4.10e-02 9.08e-01
GO:0003697 single-stranded DNA binding 67 5.65e-01 -4.07e-02 8.79e-01
GO:0005262 calcium channel activity 22 7.42e-01 -4.06e-02 9.40e-01
GO:0005634 nucleus 2127 2.78e-03 -4.06e-02 1.36e-01
GO:0007040 lysosome organization 33 6.87e-01 4.05e-02 9.28e-01
GO:0019827 stem cell population maintenance 21 7.48e-01 4.04e-02 9.40e-01
GO:0034644 cellular response to UV 33 6.89e-01 4.03e-02 9.28e-01
GO:0006260 DNA replication 34 6.84e-01 4.03e-02 9.27e-01
GO:0042752 regulation of circadian rhythm 27 7.18e-01 4.02e-02 9.39e-01
GO:0030182 neuron differentiation 57 6.01e-01 -4.01e-02 8.96e-01
GO:0005506 iron ion binding 64 5.80e-01 -4.00e-02 8.85e-01
GO:0001726 ruffle 43 6.51e-01 -3.99e-02 9.14e-01
GO:0001654 eye development 17 7.78e-01 -3.96e-02 9.47e-01
GO:0010839 negative regulation of keratinocyte proliferation 14 7.98e-01 -3.95e-02 9.55e-01
GO:0050808 synapse organization 17 7.79e-01 -3.94e-02 9.47e-01
GO:0048015 phosphatidylinositol-mediated signaling 18 7.73e-01 -3.93e-02 9.47e-01
GO:0031116 positive regulation of microtubule polymerization 11 8.22e-01 3.92e-02 9.61e-01
GO:0003682 chromatin binding 238 3.00e-01 3.91e-02 7.47e-01
GO:0000781 chromosome, telomeric region 75 5.59e-01 -3.91e-02 8.78e-01
GO:0070936 protein K48-linked ubiquitination 68 5.79e-01 -3.90e-02 8.85e-01
GO:0004602 glutathione peroxidase activity 12 8.16e-01 -3.89e-02 9.61e-01
GO:0046983 protein dimerization activity 70 5.74e-01 3.89e-02 8.84e-01
GO:0070161 anchoring junction 15 7.95e-01 3.88e-02 9.54e-01
GO:0032481 positive regulation of type I interferon production 18 7.76e-01 -3.87e-02 9.47e-01
GO:0042632 cholesterol homeostasis 39 6.76e-01 3.86e-02 9.25e-01
GO:0035725 sodium ion transmembrane transport 47 6.47e-01 -3.86e-02 9.13e-01
GO:0043588 skin development 22 7.55e-01 -3.84e-02 9.42e-01
GO:0015485 cholesterol binding 29 7.23e-01 -3.81e-02 9.39e-01
GO:0004674 protein serine/threonine kinase activity 202 3.53e-01 3.80e-02 7.80e-01
GO:0006935 chemotaxis 14 8.06e-01 3.80e-02 9.59e-01
GO:0004715 non-membrane spanning protein tyrosine kinase activity 20 7.74e-01 -3.71e-02 9.47e-01
GO:0001736 establishment of planar polarity 12 8.24e-01 -3.71e-02 9.61e-01
GO:0002230 positive regulation of defense response to virus by host 11 8.32e-01 -3.69e-02 9.66e-01
GO:0045732 positive regulation of protein catabolic process 46 6.66e-01 -3.68e-02 9.18e-01
GO:0001778 plasma membrane repair 16 7.99e-01 3.68e-02 9.55e-01
GO:0007389 pattern specification process 14 8.12e-01 -3.67e-02 9.61e-01
GO:0035264 multicellular organism growth 66 6.06e-01 -3.67e-02 8.98e-01
GO:0008380 RNA splicing 47 6.64e-01 -3.67e-02 9.17e-01
GO:0003729 mRNA binding 145 4.52e-01 3.63e-02 8.29e-01
GO:0070182 DNA polymerase binding 13 8.21e-01 -3.62e-02 9.61e-01
GO:0000791 euchromatin 29 7.36e-01 -3.61e-02 9.40e-01
GO:0004930 G protein-coupled receptor activity 55 6.44e-01 3.61e-02 9.11e-01
GO:0034314 Arp2/3 complex-mediated actin nucleation 11 8.37e-01 -3.59e-02 9.69e-01
GO:0045211 postsynaptic membrane 57 6.42e-01 -3.57e-02 9.11e-01
GO:0006302 double-strand break repair 45 6.80e-01 3.55e-02 9.25e-01
GO:0098552 side of membrane 14 8.18e-01 3.55e-02 9.61e-01
GO:0003689 DNA clamp loader activity 32 7.32e-01 3.50e-02 9.40e-01
GO:0034237 protein kinase A regulatory subunit binding 14 8.22e-01 3.47e-02 9.61e-01
GO:0030165 PDZ domain binding 29 7.48e-01 3.45e-02 9.40e-01
GO:0048487 beta-tubulin binding 22 7.80e-01 3.44e-02 9.47e-01
GO:0002039 p53 binding 44 6.94e-01 -3.43e-02 9.30e-01
GO:0045944 positive regulation of transcription by RNA polymerase II 526 1.82e-01 3.42e-02 6.90e-01
GO:0019899 enzyme binding 111 5.35e-01 -3.41e-02 8.72e-01
GO:0005543 phospholipid binding 38 7.17e-01 -3.40e-02 9.39e-01
GO:0017053 transcription repressor complex 34 7.32e-01 -3.39e-02 9.40e-01
GO:0030863 cortical cytoskeleton 10 8.53e-01 -3.38e-02 9.75e-01
GO:0031145 anaphase-promoting complex-dependent catabolic process 14 8.27e-01 3.38e-02 9.62e-01
GO:0005654 nucleoplasm 1533 3.07e-02 -3.37e-02 3.62e-01
GO:0010761 fibroblast migration 10 8.55e-01 -3.35e-02 9.75e-01
GO:0000139 Golgi membrane 260 3.55e-01 -3.34e-02 7.82e-01
GO:0030234 enzyme regulator activity 14 8.30e-01 3.32e-02 9.63e-01
GO:0005524 ATP binding 889 9.70e-02 3.32e-02 5.95e-01
GO:0048488 synaptic vesicle endocytosis 20 7.98e-01 3.30e-02 9.55e-01
GO:0050680 negative regulation of epithelial cell proliferation 24 7.80e-01 -3.30e-02 9.47e-01
GO:0030864 cortical actin cytoskeleton 32 7.47e-01 -3.30e-02 9.40e-01
GO:0030335 positive regulation of cell migration 105 5.61e-01 -3.29e-02 8.78e-01
GO:0007399 nervous system development 89 5.92e-01 3.29e-02 8.90e-01
GO:0021987 cerebral cortex development 25 7.76e-01 -3.29e-02 9.47e-01
GO:0019915 lipid storage 11 8.51e-01 3.28e-02 9.75e-01
GO:0032922 circadian regulation of gene expression 34 7.41e-01 3.27e-02 9.40e-01
GO:0046330 positive regulation of JNK cascade 38 7.28e-01 3.27e-02 9.39e-01
GO:0005901 caveola 28 7.65e-01 -3.26e-02 9.47e-01
GO:0071949 FAD binding 27 7.70e-01 3.26e-02 9.47e-01
GO:0007166 cell surface receptor signaling pathway 40 7.22e-01 -3.26e-02 9.39e-01
GO:0015297 antiporter activity 18 8.11e-01 3.25e-02 9.61e-01
GO:0019838 growth factor binding 11 8.52e-01 3.24e-02 9.75e-01
GO:0046872 metal ion binding 871 1.09e-01 3.24e-02 5.96e-01
GO:0030141 secretory granule 18 8.13e-01 -3.23e-02 9.61e-01
GO:0090102 cochlea development 12 8.47e-01 3.23e-02 9.73e-01
GO:0034614 cellular response to reactive oxygen species 16 8.24e-01 3.22e-02 9.61e-01
GO:0070273 phosphatidylinositol-4-phosphate binding 16 8.24e-01 3.22e-02 9.61e-01
GO:0007338 single fertilization 19 8.10e-01 3.18e-02 9.61e-01
GO:0016567 protein ubiquitination 155 4.95e-01 3.18e-02 8.60e-01
GO:0030097 hemopoiesis 25 7.83e-01 3.18e-02 9.47e-01
GO:0005886 plasma membrane 1514 4.33e-02 3.17e-02 4.31e-01
GO:0030838 positive regulation of actin filament polymerization 27 7.76e-01 3.16e-02 9.47e-01
GO:0000122 negative regulation of transcription by RNA polymerase II 395 2.86e-01 -3.14e-02 7.44e-01
GO:0010468 regulation of gene expression 58 6.79e-01 -3.14e-02 9.25e-01
GO:0019005 SCF ubiquitin ligase complex 43 7.22e-01 -3.13e-02 9.39e-01
GO:0001664 G protein-coupled receptor binding 21 8.04e-01 3.13e-02 9.59e-01
GO:0005765 lysosomal membrane 137 5.32e-01 3.09e-02 8.72e-01
GO:0070888 E-box binding 21 8.06e-01 -3.09e-02 9.60e-01
GO:0000209 protein polyubiquitination 77 6.40e-01 -3.08e-02 9.11e-01
GO:0051259 protein complex oligomerization 14 8.42e-01 -3.08e-02 9.72e-01
GO:0004198 calcium-dependent cysteine-type endopeptidase activity 10 8.67e-01 3.06e-02 9.78e-01
GO:0031647 regulation of protein stability 57 6.90e-01 -3.06e-02 9.28e-01
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding 84 6.30e-01 -3.04e-02 9.06e-01
GO:0000987 cis-regulatory region sequence-specific DNA binding 21 8.10e-01 -3.03e-02 9.61e-01
GO:0030507 spectrin binding 12 8.56e-01 3.03e-02 9.75e-01
GO:0007229 integrin-mediated signaling pathway 44 7.28e-01 3.03e-02 9.39e-01
GO:0007417 central nervous system development 41 7.38e-01 -3.02e-02 9.40e-01
GO:0015035 protein-disulfide reductase activity 14 8.46e-01 -3.01e-02 9.73e-01
GO:0042407 cristae formation 11 8.63e-01 -3.01e-02 9.78e-01
GO:0008143 poly(A) binding 13 8.52e-01 -2.99e-02 9.75e-01
GO:0005975 carbohydrate metabolic process 49 7.17e-01 -2.99e-02 9.39e-01
GO:0005769 early endosome 141 5.42e-01 2.98e-02 8.74e-01
GO:0070085 glycosylation 14 8.47e-01 -2.98e-02 9.73e-01
GO:0019900 kinase binding 48 7.21e-01 -2.98e-02 9.39e-01
GO:0005813 centrosome 343 3.46e-01 -2.97e-02 7.79e-01
GO:0003777 microtubule motor activity 23 8.05e-01 -2.97e-02 9.59e-01
GO:0010008 endosome membrane 86 6.35e-01 2.96e-02 9.08e-01
GO:0005815 microtubule organizing center 37 7.56e-01 2.96e-02 9.42e-01
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 156 5.25e-01 -2.95e-02 8.70e-01
GO:0045111 intermediate filament cytoskeleton 23 8.07e-01 2.94e-02 9.60e-01
GO:0005049 nuclear export signal receptor activity 10 8.74e-01 -2.90e-02 9.78e-01
GO:0006346 DNA methylation-dependent constitutive heterochromatin formation 10 8.74e-01 -2.90e-02 9.78e-01
GO:0051537 2 iron, 2 sulfur cluster binding 17 8.37e-01 2.88e-02 9.69e-01
GO:0016485 protein processing 40 7.55e-01 2.86e-02 9.42e-01
GO:0050840 extracellular matrix binding 17 8.39e-01 2.84e-02 9.71e-01
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 13 8.59e-01 -2.84e-02 9.76e-01
GO:0070979 protein K11-linked ubiquitination 22 8.18e-01 2.83e-02 9.61e-01
GO:0008543 fibroblast growth factor receptor signaling pathway 36 7.70e-01 2.82e-02 9.47e-01
GO:0002250 adaptive immune response 20 8.28e-01 -2.81e-02 9.62e-01
GO:0061351 neural precursor cell proliferation 14 8.57e-01 -2.79e-02 9.75e-01
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 30 7.92e-01 -2.78e-02 9.53e-01
GO:0016740 transferase activity 23 8.19e-01 -2.75e-02 9.61e-01
GO:0006631 fatty acid metabolic process 34 7.83e-01 2.73e-02 9.47e-01
GO:0042177 negative regulation of protein catabolic process 23 8.21e-01 -2.73e-02 9.61e-01
GO:0046875 ephrin receptor binding 17 8.46e-01 2.71e-02 9.73e-01
GO:0034142 toll-like receptor 4 signaling pathway 14 8.60e-01 -2.71e-02 9.77e-01
GO:0003688 DNA replication origin binding 12 8.71e-01 2.71e-02 9.78e-01
GO:0061709 reticulophagy 15 8.56e-01 2.71e-02 9.75e-01
GO:0005509 calcium ion binding 257 4.57e-01 2.70e-02 8.31e-01
GO:0043410 positive regulation of MAPK cascade 61 7.15e-01 -2.70e-02 9.39e-01
GO:0030968 endoplasmic reticulum unfolded protein response 30 7.98e-01 2.70e-02 9.55e-01
GO:0060391 positive regulation of SMAD protein signal transduction 13 8.68e-01 -2.67e-02 9.78e-01
GO:0000045 autophagosome assembly 53 7.37e-01 -2.66e-02 9.40e-01
GO:0005871 kinesin complex 22 8.29e-01 -2.65e-02 9.63e-01
GO:0043014 alpha-tubulin binding 23 8.27e-01 2.63e-02 9.62e-01
GO:0007004 telomere maintenance via telomerase 11 8.80e-01 2.62e-02 9.78e-01
GO:0008270 zinc ion binding 401 3.71e-01 2.62e-02 7.90e-01
GO:0072657 protein localization to membrane 19 8.44e-01 -2.61e-02 9.73e-01
GO:0030134 COPII-coated ER to Golgi transport vesicle 21 8.37e-01 -2.60e-02 9.69e-01
GO:0005615 extracellular space 397 3.78e-01 -2.59e-02 7.90e-01
GO:0035329 hippo signaling 18 8.50e-01 -2.58e-02 9.75e-01
GO:0042981 regulation of apoptotic process 54 7.45e-01 2.56e-02 9.40e-01
GO:0030308 negative regulation of cell growth 42 7.76e-01 -2.54e-02 9.47e-01
GO:0031410 cytoplasmic vesicle 105 6.54e-01 2.54e-02 9.14e-01
GO:0046329 negative regulation of JNK cascade 12 8.79e-01 2.53e-02 9.78e-01
GO:0004864 protein phosphatase inhibitor activity 13 8.75e-01 2.52e-02 9.78e-01
GO:0046677 response to antibiotic 13 8.75e-01 -2.52e-02 9.78e-01
GO:0005788 endoplasmic reticulum lumen 40 7.83e-01 -2.52e-02 9.47e-01
GO:0020037 heme binding 50 7.59e-01 -2.51e-02 9.44e-01
GO:0046849 bone remodeling 10 8.92e-01 -2.48e-02 9.81e-01
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT 13 8.77e-01 -2.48e-02 9.78e-01
GO:0090316 positive regulation of intracellular protein transport 14 8.73e-01 2.47e-02 9.78e-01
GO:0007010 cytoskeleton organization 51 7.63e-01 2.45e-02 9.46e-01
GO:0007267 cell-cell signaling 13 8.80e-01 2.41e-02 9.78e-01
GO:0060170 ciliary membrane 20 8.52e-01 -2.41e-02 9.75e-01
GO:0032715 negative regulation of interleukin-6 production 14 8.77e-01 2.40e-02 9.78e-01
GO:0098685 Schaffer collateral - CA1 synapse 45 7.81e-01 2.40e-02 9.47e-01
GO:0071260 cellular response to mechanical stimulus 23 8.43e-01 2.39e-02 9.72e-01
GO:1903543 positive regulation of exosomal secretion 10 8.96e-01 -2.39e-02 9.81e-01
GO:0050681 nuclear androgen receptor binding 16 8.69e-01 -2.39e-02 9.78e-01
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific 346 4.53e-01 -2.36e-02 8.29e-01
GO:0006402 mRNA catabolic process 14 8.79e-01 2.35e-02 9.78e-01
GO:0034599 cellular response to oxidative stress 44 7.88e-01 -2.35e-02 9.50e-01
GO:0070301 cellular response to hydrogen peroxide 23 8.46e-01 2.33e-02 9.73e-01
GO:0048384 retinoic acid receptor signaling pathway 11 8.94e-01 -2.32e-02 9.81e-01
GO:0005977 glycogen metabolic process 13 8.86e-01 -2.30e-02 9.78e-01
GO:0006606 protein import into nucleus 62 7.56e-01 -2.29e-02 9.42e-01
GO:0005829 cytosol 2012 1.00e-01 -2.28e-02 5.95e-01
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 14 8.83e-01 -2.27e-02 9.78e-01
GO:0017056 structural constituent of nuclear pore 19 8.65e-01 2.25e-02 9.78e-01
GO:0004867 serine-type endopeptidase inhibitor activity 21 8.59e-01 2.24e-02 9.76e-01
GO:0061630 ubiquitin protein ligase activity 176 6.09e-01 2.24e-02 8.98e-01
GO:0006352 DNA-templated transcription initiation 11 8.98e-01 2.23e-02 9.81e-01
GO:0051726 regulation of cell cycle 104 6.95e-01 -2.23e-02 9.30e-01
GO:0008017 microtubule binding 152 6.41e-01 -2.20e-02 9.11e-01
GO:0031625 ubiquitin protein ligase binding 172 6.20e-01 -2.20e-02 9.03e-01
GO:0031965 nuclear membrane 119 6.82e-01 2.18e-02 9.25e-01
GO:0031369 translation initiation factor binding 12 8.96e-01 2.17e-02 9.81e-01
GO:0043524 negative regulation of neuron apoptotic process 51 7.89e-01 2.16e-02 9.51e-01
GO:0012507 ER to Golgi transport vesicle membrane 11 9.02e-01 2.15e-02 9.81e-01
GO:0048027 mRNA 5’-UTR binding 19 8.71e-01 -2.15e-02 9.78e-01
GO:1902600 proton transmembrane transport 59 7.77e-01 -2.13e-02 9.47e-01
GO:0007286 spermatid development 25 8.54e-01 -2.13e-02 9.75e-01
GO:0032991 protein-containing complex 206 5.99e-01 -2.13e-02 8.95e-01
GO:0007018 microtubule-based movement 41 8.15e-01 2.12e-02 9.61e-01
GO:0090141 positive regulation of mitochondrial fission 16 8.84e-01 -2.11e-02 9.78e-01
GO:0097550 transcription preinitiation complex 12 8.99e-01 2.11e-02 9.81e-01
GO:0000712 resolution of meiotic recombination intermediates 14 8.92e-01 2.10e-02 9.81e-01
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 15 8.88e-01 2.09e-02 9.79e-01
GO:0006261 DNA-templated DNA replication 18 8.79e-01 -2.07e-02 9.78e-01
GO:0043484 regulation of RNA splicing 23 8.65e-01 2.05e-02 9.78e-01
GO:0008053 mitochondrial fusion 17 8.84e-01 -2.05e-02 9.78e-01
GO:0061436 establishment of skin barrier 13 8.99e-01 -2.04e-02 9.81e-01
GO:0046982 protein heterodimerization activity 131 6.89e-01 -2.03e-02 9.28e-01
GO:0008344 adult locomotory behavior 23 8.66e-01 -2.03e-02 9.78e-01
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity 16 8.89e-01 -2.01e-02 9.79e-01
GO:0035861 site of double-strand break 58 7.92e-01 2.00e-02 9.53e-01
GO:0001501 skeletal system development 34 8.40e-01 2.00e-02 9.71e-01
GO:0050727 regulation of inflammatory response 26 8.61e-01 1.99e-02 9.77e-01
GO:0030672 synaptic vesicle membrane 43 8.23e-01 -1.97e-02 9.61e-01
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 20 8.79e-01 -1.96e-02 9.78e-01
GO:0007020 microtubule nucleation 14 8.99e-01 -1.96e-02 9.81e-01
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding 392 5.09e-01 -1.95e-02 8.62e-01
GO:1990837 sequence-specific double-stranded DNA binding 47 8.18e-01 -1.94e-02 9.61e-01
GO:0046835 carbohydrate phosphorylation 20 8.82e-01 -1.93e-02 9.78e-01
GO:0006096 glycolytic process 23 8.74e-01 1.92e-02 9.78e-01
GO:0033627 cell adhesion mediated by integrin 22 8.77e-01 -1.91e-02 9.78e-01
GO:0042147 retrograde transport, endosome to Golgi 50 8.16e-01 1.90e-02 9.61e-01
GO:0009408 response to heat 19 8.86e-01 1.90e-02 9.78e-01
GO:0031902 late endosome membrane 67 7.88e-01 -1.90e-02 9.50e-01
GO:0002224 toll-like receptor signaling pathway 14 9.02e-01 1.89e-02 9.81e-01
GO:0000175 3’-5’-RNA exonuclease activity 21 8.81e-01 -1.88e-02 9.78e-01
GO:0030971 receptor tyrosine kinase binding 32 8.56e-01 -1.86e-02 9.75e-01
GO:0061157 mRNA destabilization 12 9.11e-01 1.85e-02 9.83e-01
GO:0099175 regulation of postsynapse organization 20 8.87e-01 1.83e-02 9.79e-01
GO:0005876 spindle microtubule 20 8.87e-01 -1.83e-02 9.79e-01
GO:0005680 anaphase-promoting complex 13 9.11e-01 -1.79e-02 9.83e-01
GO:1904047 S-adenosyl-L-methionine binding 13 9.13e-01 -1.74e-02 9.83e-01
GO:1900182 positive regulation of protein localization to nucleus 25 8.80e-01 -1.74e-02 9.78e-01
GO:0030904 retromer complex 15 9.08e-01 -1.72e-02 9.83e-01
GO:0005776 autophagosome 42 8.47e-01 1.72e-02 9.73e-01
GO:0003684 damaged DNA binding 34 8.64e-01 1.70e-02 9.78e-01
GO:0010718 positive regulation of epithelial to mesenchymal transition 26 8.81e-01 1.70e-02 9.78e-01
GO:0016757 glycosyltransferase activity 14 9.13e-01 1.69e-02 9.83e-01
GO:0060976 coronary vasculature development 17 9.04e-01 1.69e-02 9.81e-01
GO:0006513 protein monoubiquitination 27 8.81e-01 1.66e-02 9.78e-01
GO:0090575 RNA polymerase II transcription regulator complex 53 8.35e-01 1.65e-02 9.68e-01
GO:0005737 cytoplasm 2166 2.29e-01 -1.62e-02 7.13e-01
GO:0005516 calmodulin binding 66 8.21e-01 1.61e-02 9.61e-01
GO:0008076 voltage-gated potassium channel complex 19 9.03e-01 -1.61e-02 9.81e-01
GO:0008305 integrin complex 17 9.09e-01 -1.61e-02 9.83e-01
GO:0031464 Cul4A-RING E3 ubiquitin ligase complex 10 9.30e-01 1.60e-02 9.86e-01
GO:0001649 osteoblast differentiation 39 8.63e-01 1.59e-02 9.78e-01
GO:0071466 cellular response to xenobiotic stimulus 24 8.93e-01 -1.59e-02 9.81e-01
GO:0051017 actin filament bundle assembly 13 9.22e-01 -1.56e-02 9.86e-01
GO:0034451 centriolar satellite 74 8.18e-01 -1.55e-02 9.61e-01
GO:0071577 zinc ion transmembrane transport 10 9.32e-01 -1.55e-02 9.86e-01
GO:0002218 activation of innate immune response 17 9.12e-01 1.54e-02 9.83e-01
GO:0140297 DNA-binding transcription factor binding 71 8.23e-01 -1.53e-02 9.61e-01
GO:0071363 cellular response to growth factor stimulus 19 9.09e-01 1.52e-02 9.83e-01
GO:0051216 cartilage development 20 9.07e-01 -1.52e-02 9.83e-01
GO:0000724 double-strand break repair via homologous recombination 71 8.25e-01 1.52e-02 9.61e-01
GO:0098978 glutamatergic synapse 229 6.95e-01 1.51e-02 9.30e-01
GO:0032868 response to insulin 22 9.03e-01 -1.50e-02 9.81e-01
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 19 9.10e-01 -1.50e-02 9.83e-01
GO:0032880 regulation of protein localization 42 8.69e-01 -1.47e-02 9.78e-01
GO:0032956 regulation of actin cytoskeleton organization 37 8.77e-01 1.47e-02 9.78e-01
GO:0001837 epithelial to mesenchymal transition 16 9.20e-01 1.46e-02 9.86e-01
GO:0009897 external side of plasma membrane 108 7.94e-01 1.45e-02 9.54e-01
GO:0000159 protein phosphatase type 2A complex 12 9.31e-01 -1.44e-02 9.86e-01
GO:0004713 protein tyrosine kinase activity 34 8.84e-01 1.44e-02 9.78e-01
GO:0032212 positive regulation of telomere maintenance via telomerase 17 9.18e-01 1.44e-02 9.86e-01
GO:0009986 cell surface 181 7.39e-01 1.44e-02 9.40e-01
GO:0034707 chloride channel complex 10 9.37e-01 1.43e-02 9.86e-01
GO:1902895 positive regulation of miRNA transcription 24 9.04e-01 -1.42e-02 9.81e-01
GO:0040014 regulation of multicellular organism growth 12 9.32e-01 -1.42e-02 9.86e-01
GO:0036342 post-anal tail morphogenesis 11 9.36e-01 -1.40e-02 9.86e-01
GO:0016605 PML body 61 8.50e-01 1.40e-02 9.75e-01
GO:0003281 ventricular septum development 15 9.26e-01 -1.39e-02 9.86e-01
GO:0030513 positive regulation of BMP signaling pathway 19 9.17e-01 -1.38e-02 9.86e-01
GO:0065003 protein-containing complex assembly 37 8.86e-01 1.37e-02 9.78e-01
GO:0007163 establishment or maintenance of cell polarity 13 9.33e-01 -1.36e-02 9.86e-01
GO:0045943 positive regulation of transcription by RNA polymerase I 11 9.38e-01 -1.35e-02 9.86e-01
GO:0060271 cilium assembly 126 7.93e-01 1.35e-02 9.54e-01
GO:0006865 amino acid transport 11 9.39e-01 1.34e-02 9.86e-01
GO:0007165 signal transduction 264 7.19e-01 -1.29e-02 9.39e-01
GO:0005881 cytoplasmic microtubule 30 9.03e-01 1.28e-02 9.81e-01
GO:0000381 regulation of alternative mRNA splicing, via spliceosome 31 9.03e-01 -1.27e-02 9.81e-01
GO:0036126 sperm flagellum 33 9.02e-01 -1.24e-02 9.81e-01
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 112 8.21e-01 -1.24e-02 9.61e-01
GO:0060337 type I interferon-mediated signaling pathway 10 9.47e-01 -1.21e-02 9.89e-01
GO:0044183 protein folding chaperone 21 9.24e-01 -1.20e-02 9.86e-01
GO:0016020 membrane 944 5.36e-01 -1.20e-02 8.72e-01
GO:0005507 copper ion binding 22 9.22e-01 1.20e-02 9.86e-01
GO:0140693 molecular condensate scaffold activity 24 9.20e-01 1.19e-02 9.86e-01
GO:0001666 response to hypoxia 50 8.86e-01 1.17e-02 9.78e-01
GO:0030246 carbohydrate binding 40 8.98e-01 1.17e-02 9.81e-01
GO:0001817 regulation of cytokine production 26 9.18e-01 1.17e-02 9.86e-01
GO:0043001 Golgi to plasma membrane protein transport 21 9.28e-01 -1.15e-02 9.86e-01
GO:0042277 peptide binding 10 9.52e-01 -1.10e-02 9.89e-01
GO:0005721 pericentric heterochromatin 18 9.35e-01 -1.10e-02 9.86e-01
GO:0007162 negative regulation of cell adhesion 17 9.38e-01 -1.08e-02 9.86e-01
GO:0031514 motile cilium 37 9.09e-01 -1.08e-02 9.83e-01
GO:0043005 neuron projection 95 8.56e-01 -1.08e-02 9.75e-01
GO:0003700 DNA-binding transcription factor activity 78 8.69e-01 1.08e-02 9.78e-01
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 28 9.22e-01 1.08e-02 9.86e-01
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 182 8.04e-01 1.07e-02 9.59e-01
GO:0007259 cell surface receptor signaling pathway via JAK-STAT 22 9.31e-01 1.06e-02 9.86e-01
GO:0031072 heat shock protein binding 27 9.25e-01 1.05e-02 9.86e-01
GO:0007009 plasma membrane organization 10 9.55e-01 1.03e-02 9.89e-01
GO:0007281 germ cell development 14 9.48e-01 1.02e-02 9.89e-01
GO:0032024 positive regulation of insulin secretion 21 9.36e-01 1.02e-02 9.86e-01
GO:0097352 autophagosome maturation 24 9.31e-01 1.02e-02 9.86e-01
GO:0007029 endoplasmic reticulum organization 16 9.44e-01 -1.01e-02 9.88e-01
GO:0043525 positive regulation of neuron apoptotic process 18 9.42e-01 -9.95e-03 9.87e-01
GO:0030170 pyridoxal phosphate binding 33 9.21e-01 -9.93e-03 9.86e-01
GO:0005905 clathrin-coated pit 30 9.26e-01 -9.78e-03 9.86e-01
GO:0006974 DNA damage response 120 8.54e-01 -9.74e-03 9.75e-01
GO:0106222 lncRNA binding 17 9.45e-01 -9.69e-03 9.88e-01
GO:0032869 cellular response to insulin stimulus 33 9.23e-01 9.68e-03 9.86e-01
GO:0016922 nuclear receptor binding 21 9.39e-01 -9.61e-03 9.86e-01
GO:0033077 T cell differentiation in thymus 18 9.44e-01 -9.48e-03 9.88e-01
GO:0032266 phosphatidylinositol-3-phosphate binding 31 9.28e-01 9.36e-03 9.86e-01
GO:0071230 cellular response to amino acid stimulus 29 9.31e-01 9.26e-03 9.86e-01
GO:0045494 photoreceptor cell maintenance 24 9.37e-01 9.25e-03 9.86e-01
GO:0006367 transcription initiation at RNA polymerase II promoter 20 9.43e-01 -9.23e-03 9.87e-01
GO:0050660 flavin adenine dinucleotide binding 33 9.28e-01 -9.10e-03 9.86e-01
GO:0007224 smoothened signaling pathway 50 9.12e-01 9.07e-03 9.83e-01
GO:0043565 sequence-specific DNA binding 56 9.09e-01 -8.86e-03 9.83e-01
GO:0006654 phosphatidic acid biosynthetic process 11 9.60e-01 -8.80e-03 9.90e-01
GO:0032757 positive regulation of interleukin-8 production 17 9.50e-01 -8.80e-03 9.89e-01
GO:0030326 embryonic limb morphogenesis 14 9.55e-01 8.62e-03 9.89e-01
GO:0030514 negative regulation of BMP signaling pathway 27 9.38e-01 8.59e-03 9.86e-01
GO:0031333 negative regulation of protein-containing complex assembly 16 9.53e-01 -8.52e-03 9.89e-01
GO:0006511 ubiquitin-dependent protein catabolic process 117 8.74e-01 8.52e-03 9.78e-01
GO:0035102 PRC1 complex 13 9.58e-01 8.50e-03 9.89e-01
GO:0016525 negative regulation of angiogenesis 35 9.31e-01 -8.48e-03 9.86e-01
GO:0045121 membrane raft 73 9.01e-01 -8.46e-03 9.81e-01
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 43 9.25e-01 8.35e-03 9.86e-01
GO:0051607 defense response to virus 56 9.15e-01 8.27e-03 9.84e-01
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 14 9.58e-01 8.20e-03 9.89e-01
GO:0045022 early endosome to late endosome transport 19 9.51e-01 -8.14e-03 9.89e-01
GO:0034198 cellular response to amino acid starvation 31 9.38e-01 -8.10e-03 9.86e-01
GO:0048471 perinuclear region of cytoplasm 286 8.15e-01 8.09e-03 9.61e-01
GO:0003676 nucleic acid binding 106 8.92e-01 7.63e-03 9.81e-01
GO:0031681 G-protein beta-subunit binding 10 9.68e-01 -7.43e-03 9.90e-01
GO:0045773 positive regulation of axon extension 10 9.68e-01 -7.39e-03 9.90e-01
GO:0031648 protein destabilization 32 9.43e-01 7.31e-03 9.87e-01
GO:0045335 phagocytic vesicle 35 9.41e-01 -7.21e-03 9.87e-01
GO:0055037 recycling endosome 56 9.26e-01 7.20e-03 9.86e-01
GO:0060412 ventricular septum morphogenesis 18 9.58e-01 -7.09e-03 9.89e-01
GO:0045216 cell-cell junction organization 13 9.65e-01 -7.08e-03 9.90e-01
GO:0071806 protein transmembrane transport 12 9.67e-01 -6.88e-03 9.90e-01
GO:0031491 nucleosome binding 25 9.54e-01 6.73e-03 9.89e-01
GO:0009982 pseudouridine synthase activity 12 9.69e-01 -6.58e-03 9.90e-01
GO:0002102 podosome 17 9.64e-01 -6.34e-03 9.90e-01
GO:0031175 neuron projection development 48 9.40e-01 -6.27e-03 9.87e-01
GO:0051403 stress-activated MAPK cascade 12 9.70e-01 -6.21e-03 9.90e-01
GO:0042391 regulation of membrane potential 12 9.71e-01 6.15e-03 9.90e-01
GO:0006357 regulation of transcription by RNA polymerase II 548 8.11e-01 6.02e-03 9.61e-01
GO:0051287 NAD binding 18 9.65e-01 -5.92e-03 9.90e-01
GO:0031593 polyubiquitin modification-dependent protein binding 19 9.65e-01 -5.80e-03 9.90e-01
GO:0006281 DNA repair 95 9.25e-01 -5.57e-03 9.86e-01
GO:0048854 brain morphogenesis 14 9.72e-01 -5.45e-03 9.90e-01
GO:0097191 extrinsic apoptotic signaling pathway 20 9.67e-01 5.36e-03 9.90e-01
GO:0061512 protein localization to cilium 22 9.66e-01 -5.29e-03 9.90e-01
GO:0005777 peroxisome 49 9.50e-01 -5.20e-03 9.89e-01
GO:0070402 NADPH binding 10 9.78e-01 -5.14e-03 9.92e-01
GO:0071805 potassium ion transmembrane transport 38 9.57e-01 -5.10e-03 9.89e-01
GO:0043596 nuclear replication fork 10 9.78e-01 5.08e-03 9.92e-01
GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction 21 9.69e-01 -4.92e-03 9.90e-01
GO:0045893 positive regulation of DNA-templated transcription 223 9.02e-01 -4.80e-03 9.81e-01
GO:0016251 RNA polymerase II general transcription initiation factor activity 22 9.69e-01 4.77e-03 9.90e-01
GO:0005923 bicellular tight junction 49 9.55e-01 -4.69e-03 9.89e-01
GO:0016358 dendrite development 18 9.73e-01 4.67e-03 9.90e-01
GO:1990756 ubiquitin-like ligase-substrate adaptor activity 71 9.47e-01 4.58e-03 9.89e-01
GO:0070062 extracellular exosome 39 9.61e-01 4.52e-03 9.90e-01
GO:0070374 positive regulation of ERK1 and ERK2 cascade 59 9.54e-01 4.39e-03 9.89e-01
GO:0009411 response to UV 23 9.72e-01 4.29e-03 9.90e-01
GO:0060326 cell chemotaxis 28 9.69e-01 -4.27e-03 9.90e-01
GO:0098869 cellular oxidant detoxification 28 9.69e-01 -4.26e-03 9.90e-01
GO:0001822 kidney development 51 9.58e-01 -4.26e-03 9.89e-01
GO:0086091 regulation of heart rate by cardiac conduction 16 9.78e-01 -4.07e-03 9.92e-01
GO:0003677 DNA binding 336 8.99e-01 4.05e-03 9.81e-01
GO:0006633 fatty acid biosynthetic process 22 9.74e-01 3.95e-03 9.91e-01
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 13 9.80e-01 3.92e-03 9.92e-01
GO:0051010 microtubule plus-end binding 11 9.82e-01 3.82e-03 9.94e-01
GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction 76 9.56e-01 -3.70e-03 9.89e-01
GO:2000042 negative regulation of double-strand break repair via homologous recombination 16 9.80e-01 -3.69e-03 9.92e-01
GO:0030890 positive regulation of B cell proliferation 21 9.78e-01 -3.44e-03 9.92e-01
GO:0006897 endocytosis 91 9.57e-01 -3.24e-03 9.89e-01
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 12 9.85e-01 3.13e-03 9.95e-01
GO:0005874 microtubule 131 9.52e-01 3.05e-03 9.89e-01
GO:0004222 metalloendopeptidase activity 50 9.72e-01 -2.83e-03 9.90e-01
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 17 9.84e-01 -2.82e-03 9.94e-01
GO:0005694 chromosome 76 9.67e-01 -2.72e-03 9.90e-01
GO:0000502 proteasome complex 13 9.88e-01 -2.40e-03 9.95e-01
GO:1990573 potassium ion import across plasma membrane 18 9.87e-01 2.23e-03 9.95e-01
GO:0071347 cellular response to interleukin-1 17 9.88e-01 -2.18e-03 9.95e-01
GO:0031901 early endosome membrane 75 9.75e-01 2.09e-03 9.91e-01
GO:0044325 transmembrane transporter binding 54 9.79e-01 2.06e-03 9.92e-01
GO:0060070 canonical Wnt signaling pathway 57 9.79e-01 -2.05e-03 9.92e-01
GO:0005576 extracellular region 234 9.59e-01 1.98e-03 9.89e-01
GO:0070498 interleukin-1-mediated signaling pathway 11 9.91e-01 -1.97e-03 9.96e-01
GO:0048701 embryonic cranial skeleton morphogenesis 13 9.90e-01 1.96e-03 9.96e-01
GO:0019902 phosphatase binding 23 9.87e-01 -1.89e-03 9.95e-01
GO:0043997 histone H4K12 acetyltransferase activity 10 9.92e-01 1.89e-03 9.96e-01
GO:0036211 protein modification process 16 9.90e-01 1.88e-03 9.96e-01
GO:0031966 mitochondrial membrane 38 9.84e-01 1.86e-03 9.94e-01
GO:0052689 carboxylic ester hydrolase activity 11 9.92e-01 1.78e-03 9.96e-01
GO:0006893 Golgi to plasma membrane transport 19 9.91e-01 1.41e-03 9.96e-01
GO:0035249 synaptic transmission, glutamatergic 16 9.93e-01 -1.35e-03 9.96e-01
GO:0001786 phosphatidylserine binding 25 9.94e-01 -8.56e-04 9.97e-01
GO:0044291 cell-cell contact zone 14 9.96e-01 7.49e-04 9.98e-01
GO:0036064 ciliary basal body 102 9.97e-01 2.45e-04 9.98e-01
GO:0031462 Cul2-RING ubiquitin ligase complex 15 9.99e-01 1.68e-04 1.00e+00
GO:0005635 nuclear envelope 75 1.00e+00 3.93e-05 1.00e+00
GO:0032211 negative regulation of telomere maintenance via telomerase 10 1.00e+00 -1.40e-05 1.00e+00



Detailed Gene set reports



GO:0042474 middle ear morphogenesis
set GO:0042474 middle ear morphogenesis
setSize 10
pANOVA 0.000882
s.dist -0.607
p.adjustANOVA 0.0851


Top enriched genes
Top 20 genes
GeneID Gene Rank
NAGLU -6658
FGFR1 -6279
INSIG2 -5648
RPL38 -5584
OSR2 -5476
INSIG1 -5276
NKX3-2 -4387
OSR1 -3940
PRRX1 -848
TSHZ1 1419

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NAGLU -6658
FGFR1 -6279
INSIG2 -5648
RPL38 -5584
OSR2 -5476
INSIG1 -5276
NKX3-2 -4387
OSR1 -3940
PRRX1 -848
TSHZ1 1419



GO:0000245 spliceosomal complex assembly
set GO:0000245 spliceosomal complex assembly
setSize 10
pANOVA 0.0021
s.dist -0.562
p.adjustANOVA 0.123


Top enriched genes
Top 20 genes
GeneID Gene Rank
RSRP1 -6832
USP39 -6274
SF3B1 -5674
ZRSR2 -5609
SRPK2 -5294
SF3A2 -5152
RBM10 -5086
PRPF19 -3930
SRPK1 310
SCAF11 4141

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RSRP1 -6832
USP39 -6274
SF3B1 -5674
ZRSR2 -5609
SRPK2 -5294
SF3A2 -5152
RBM10 -5086
PRPF19 -3930
SRPK1 310
SCAF11 4141



GO:0022625 cytosolic large ribosomal subunit
set GO:0022625 cytosolic large ribosomal subunit
setSize 40
pANOVA 1.3e-09
s.dist -0.554
p.adjustANOVA 7.64e-07


Top enriched genes
Top 20 genes
GeneID Gene Rank
RPL13 -6792
RPL15 -6620
RPL37 -6536
RPL37A -6459
RPL23A -6416
RPL6 -6360
RPL26L1 -6347
RPL11 -6067
RPL10A -6007
RPL19 -5987
RPL9 -5963
RPL30 -5752
RPL38 -5584
RPL3L -5330
RPL14 -5299
RPL34 -5190
RPL5 -5117
RPL23 -4952
RPL21 -4641
RPL7 -4428

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All member genes
GeneID Gene Rank
RPL13 -6792
RPL15 -6620
RPL37 -6536
RPL37A -6459
RPL23A -6416
RPL6 -6360
RPL26L1 -6347
RPL11 -6067
RPL10A -6007
RPL19 -5987
RPL9 -5963
RPL30 -5752
RPL38 -5584
RPL3L -5330
RPL14 -5299
RPL34 -5190
RPL5 -5117
RPL23 -4952
RPL21 -4641
RPL7 -4428
RPL31 -4281
RPL3 -4221
RPL12 -3798
RPL27A -3700
RPL7A -3332
RPL32 -3253
RPL36 -2938
RPL18A -2818
RPL35 -2634
RPL35A -2410
RPL29 -1913
RPLP2 -1510
RPLP0 -1405
RPL27 -1386
RPLP1 -1306
RPL7L1 -1124
RPL4 -647
RPL8 -600
RPL24 86
ZCCHC17 3850



GO:0022627 cytosolic small ribosomal subunit
set GO:0022627 cytosolic small ribosomal subunit
setSize 25
pANOVA 1.01e-05
s.dist -0.51
p.adjustANOVA 0.00253


Top enriched genes
Top 20 genes
GeneID Gene Rank
RPS28 -7063
RPS20 -6887
RPS13 -6863
RPS15A -6840
RPS26 -6503
RPS6 -6381
RPS15 -6374
RPS2 -6304
RPS14 -6281
RPS8 -5837
RPS4Y1 -4635
RPS12 -4619
RPS7 -4477
RPS3 -3707
RPS11 -3610
RPS16 -3498
RPS24 -3282
EIF2A -2803
RPS21 -2512
RPS10 -2393

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All member genes
GeneID Gene Rank
RPS28 -7063
RPS20 -6887
RPS13 -6863
RPS15A -6840
RPS26 -6503
RPS6 -6381
RPS15 -6374
RPS2 -6304
RPS14 -6281
RPS8 -5837
RPS4Y1 -4635
RPS12 -4619
RPS7 -4477
RPS3 -3707
RPS11 -3610
RPS16 -3498
RPS24 -3282
EIF2A -2803
RPS21 -2512
RPS10 -2393
RPS3A -1918
RPS23 931
RPS29 2161
RPS27L 4973
LARP4 5506



GO:0030016 myofibril
set GO:0030016 myofibril
setSize 13
pANOVA 0.00236
s.dist 0.487
p.adjustANOVA 0.13


Top enriched genes
Top 20 genes
GeneID Gene Rank
COL6A1 7112
MYH15 7069
MYL9 7037
TWF1 6724
MYH11 6701
SCO2 4983
LMOD3 4928
TMOD3 4925
TMOD4 4887
LMOD1 3332
TWF2 -3262
CALD1 -3274
MYH1B -4805

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All member genes
GeneID Gene Rank
COL6A1 7112
MYH15 7069
MYL9 7037
TWF1 6724
MYH11 6701
SCO2 4983
LMOD3 4928
TMOD3 4925
TMOD4 4887
LMOD1 3332
TWF2 -3262
CALD1 -3274
MYH1B -4805



GO:1990391 DNA repair complex
set GO:1990391 DNA repair complex
setSize 10
pANOVA 0.00823
s.dist 0.483
p.adjustANOVA 0.238


Top enriched genes
Top 20 genes
GeneID Gene Rank
BRCA2 7184
ATM 6553
TP53BP1 5199
BRCA1 5050
PHF21A 4896
ASCC2 2821
FANCI 2251
KDM1A 1141
PALB2 239
FANCD2 14

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
BRCA2 7184
ATM 6553
TP53BP1 5199
BRCA1 5050
PHF21A 4896
ASCC2 2821
FANCI 2251
KDM1A 1141
PALB2 239
FANCD2 14



GO:1990023 mitotic spindle midzone
set GO:1990023 mitotic spindle midzone
setSize 10
pANOVA 0.00835
s.dist -0.482
p.adjustANOVA 0.238


Top enriched genes
Top 20 genes
GeneID Gene Rank
PRC1 -6880
KIF18A -6673
EML1 -5312
CTTN -4835
KIF20B -4465
HNRNPU -3199
KIF18B -2972
RCC2 -543
NUMA1 108
MAP10 1087

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PRC1 -6880
KIF18A -6673
EML1 -5312
CTTN -4835
KIF20B -4465
HNRNPU -3199
KIF18B -2972
RCC2 -543
NUMA1 108
MAP10 1087



GO:0015813 L-glutamate transmembrane transport
set GO:0015813 L-glutamate transmembrane transport
setSize 11
pANOVA 0.00606
s.dist 0.478
p.adjustANOVA 0.194


Top enriched genes
Top 20 genes
GeneID Gene Rank
SLC1A4 7237
EPM2A 6596
SLC25A13 6320
SLC25A12 4636
SLC1A6 4621
SLC25A22 3959
SLC1A7 3564
SLC38A6 1628
SLC3A1 1175
TTYH3 118
SLC17A8 -1343

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All member genes
GeneID Gene Rank
SLC1A4 7237
EPM2A 6596
SLC25A13 6320
SLC25A12 4636
SLC1A6 4621
SLC25A22 3959
SLC1A7 3564
SLC38A6 1628
SLC3A1 1175
TTYH3 118
SLC17A8 -1343



GO:0001671 ATPase activator activity
set GO:0001671 ATPase activator activity
setSize 18
pANOVA 0.000473
s.dist -0.476
p.adjustANOVA 0.067


Top enriched genes
Top 20 genes
GeneID Gene Rank
HSCB -6529
DNAJA1 -6480
ATP6AP1 -6245
DNAJB2 -5900
DNAJC15 -5716
AHSA1 -5702
DNAJB1 -5647
DNAJA2 -4568
ATP1B3 -4142
DNAJB6 -3991
AHSA2 -3849
DNAJB4 -2519
TOR1AIP2 -2468
ATP1B1 -1584
DNAJC24 -164
DNAJC19 383
TOR1AIP1 569
DNAJC10 4700

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
HSCB -6529
DNAJA1 -6480
ATP6AP1 -6245
DNAJB2 -5900
DNAJC15 -5716
AHSA1 -5702
DNAJB1 -5647
DNAJA2 -4568
ATP1B3 -4142
DNAJB6 -3991
AHSA2 -3849
DNAJB4 -2519
TOR1AIP2 -2468
ATP1B1 -1584
DNAJC24 -164
DNAJC19 383
TOR1AIP1 569
DNAJC10 4700



GO:0098761 cellular response to interleukin-7
set GO:0098761 cellular response to interleukin-7
setSize 10
pANOVA 0.00959
s.dist -0.473
p.adjustANOVA 0.243


Top enriched genes
Top 20 genes
GeneID Gene Rank
YBX1 -7016
PDIA3 -6650
ATP5B -5630
GIPC1 -5260
STIP1 -5036
HSPD1 -4747
P4HB -4026
LSP1P1 -608
BTK 2568
RAD23B 3339

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
YBX1 -7016
PDIA3 -6650
ATP5B -5630
GIPC1 -5260
STIP1 -5036
HSPD1 -4747
P4HB -4026
LSP1P1 -608
BTK 2568
RAD23B 3339



GO:0002181 cytoplasmic translation
set GO:0002181 cytoplasmic translation
setSize 27
pANOVA 2.15e-05
s.dist -0.472
p.adjustANOVA 0.00472


Top enriched genes
Top 20 genes
GeneID Gene Rank
RPS28 -7063
RPL15 -6620
RPS26 -6503
RPS6 -6381
RPL6 -6360
RPL26L1 -6347
RPS14 -6281
RPL10A -6007
RPL9 -5963
RPL38 -5584
RPL31 -4281
RWDD1 -4205
ZC3H15 -3493
RPL36 -2938
RPL18A -2818
RPL35A -2410
RPL29 -1913
RPL22 -1611
RPLP0 -1405
RPLP1 -1306

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS28 -7063
RPL15 -6620
RPS26 -6503
RPS6 -6381
RPL6 -6360
RPL26L1 -6347
RPS14 -6281
RPL10A -6007
RPL9 -5963
RPL38 -5584
RPL31 -4281
RWDD1 -4205
ZC3H15 -3493
RPL36 -2938
RPL18A -2818
RPL35A -2410
RPL29 -1913
RPL22 -1611
RPLP0 -1405
RPLP1 -1306
SARS1 -1006
DRG2 -746
RPL8 -600
RPL22L1 -381
RPL24 86
RPS23 931
RPS29 2161



GO:0006730 one-carbon metabolic process
set GO:0006730 one-carbon metabolic process
setSize 13
pANOVA 0.00361
s.dist 0.466
p.adjustANOVA 0.148


Top enriched genes
Top 20 genes
GeneID Gene Rank
SFXN3 6713
MTHFD2 6027
MAT2B 5667
MTHFD1L 5367
AHCYL1 4714
MTHFD2L 4450
MAT1A 4436
GNMT 4270
FPGS 2174
SFXN1 1571
ALDH1L2 1537
AHCYL2 1020
DHFR -3524

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All member genes
GeneID Gene Rank
SFXN3 6713
MTHFD2 6027
MAT2B 5667
MTHFD1L 5367
AHCYL1 4714
MTHFD2L 4450
MAT1A 4436
GNMT 4270
FPGS 2174
SFXN1 1571
ALDH1L2 1537
AHCYL2 1020
DHFR -3524



GO:0030155 regulation of cell adhesion
set GO:0030155 regulation of cell adhesion
setSize 19
pANOVA 0.000495
s.dist 0.462
p.adjustANOVA 0.067


Top enriched genes
Top 20 genes
GeneID Gene Rank
TNC 7232
PPP1R12A 6360
SRF 6257
LAMA5 6252
PKD1 5992
PRLR 5936
S1PR1 5734
LMO7 5235
CYTIP 4763
CYTH1 4747
PTK2 3407
FAF1 3246
KIF14 2884
LAMA2 2353
PRKX 1636
LAMA3 -549
NUAK1 -869
YTHDF2 -2737
PPP1CB -3611

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TNC 7232
PPP1R12A 6360
SRF 6257
LAMA5 6252
PKD1 5992
PRLR 5936
S1PR1 5734
LMO7 5235
CYTIP 4763
CYTH1 4747
PTK2 3407
FAF1 3246
KIF14 2884
LAMA2 2353
PRKX 1636
LAMA3 -549
NUAK1 -869
YTHDF2 -2737
PPP1CB -3611



GO:0003333 amino acid transmembrane transport
set GO:0003333 amino acid transmembrane transport
setSize 10
pANOVA 0.0124
s.dist 0.457
p.adjustANOVA 0.273


Top enriched genes
Top 20 genes
GeneID Gene Rank
SLC7A11 6740
SLC38A1 6547
SLC7A5 6521
SLC38A10 5461
SLC7A6 4849
SLC38A9 3390
SLC38A7 2697
SLC38A6 1628
SLC38A2 -1992
SLC36A4 -2354

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SLC7A11 6740
SLC38A1 6547
SLC7A5 6521
SLC38A10 5461
SLC7A6 4849
SLC38A9 3390
SLC38A7 2697
SLC38A6 1628
SLC38A2 -1992
SLC36A4 -2354



GO:0035025 positive regulation of Rho protein signal transduction
set GO:0035025 positive regulation of Rho protein signal transduction
setSize 10
pANOVA 0.0126
s.dist 0.456
p.adjustANOVA 0.273


Top enriched genes
Top 20 genes
GeneID Gene Rank
ROBO1 6973
AKAP13 6601
ERBB2 5580
LPAR1 4751
F2RL1 4606
ADGRG1 4432
NET1 4068
SEMA4D 826
ARHGEF3 459
FERMT2 -4887

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All member genes
GeneID Gene Rank
ROBO1 6973
AKAP13 6601
ERBB2 5580
LPAR1 4751
F2RL1 4606
ADGRG1 4432
NET1 4068
SEMA4D 826
ARHGEF3 459
FERMT2 -4887



GO:0001965 G-protein alpha-subunit binding
set GO:0001965 G-protein alpha-subunit binding
setSize 10
pANOVA 0.0132
s.dist 0.453
p.adjustANOVA 0.273


Top enriched genes
Top 20 genes
GeneID Gene Rank
RIC8B 6419
RGS22 6307
CCDC88A 6140
F2RL1 4606
RGS10 3640
SASH1 2889
GPSM1 2727
RGS2 1610
RIC8A 1236
RGS14 -2372

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All member genes
GeneID Gene Rank
RIC8B 6419
RGS22 6307
CCDC88A 6140
F2RL1 4606
RGS10 3640
SASH1 2889
GPSM1 2727
RGS2 1610
RIC8A 1236
RGS14 -2372



GO:0005762 mitochondrial large ribosomal subunit
set GO:0005762 mitochondrial large ribosomal subunit
setSize 38
pANOVA 1.45e-06
s.dist -0.452
p.adjustANOVA 0.000604


Top enriched genes
Top 20 genes
GeneID Gene Rank
MRPL17 -7080
MRPL16 -6935
MRPL20 -6889
MRPL14 -6864
MRPL2 -6701
MRPL38 -6674
MRPL51 -6666
MRPL12 -6477
MRPL36 -6218
MRPL37 -6044
MRPS30 -5794
MRPL49 -5519
MRPS18A -5512
MPV17L2 -5222
MRPL44 -5133
MRPL28 -5015
MRPL58 -4942
MRPL42 -4622
NSUN4 -4609
NSUN3 -4099

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MRPL17 -7080
MRPL16 -6935
MRPL20 -6889
MRPL14 -6864
MRPL2 -6701
MRPL38 -6674
MRPL51 -6666
MRPL12 -6477
MRPL36 -6218
MRPL37 -6044
MRPS30 -5794
MRPL49 -5519
MRPS18A -5512
MPV17L2 -5222
MRPL44 -5133
MRPL28 -5015
MRPL58 -4942
MRPL42 -4622
NSUN4 -4609
NSUN3 -4099
MRPL39 -3994
MRPL40 -3919
MRPL23 -2992
MRPL48 -2069
MRPL13 -1955
MRPL41 -1168
MRPL3 -1146
MRPL27 -1103
MRPL15 -483
MRPL50 -184
MRPL53 133
MRPL21 559
MRPL19 774
MRPL47 945
MRPL10 2398
MRPL32 2749
MRPL46 3571
MRPL22 5313



GO:0070412 R-SMAD binding
set GO:0070412 R-SMAD binding
setSize 13
pANOVA 0.00484
s.dist -0.451
p.adjustANOVA 0.174


Top enriched genes
Top 20 genes
GeneID Gene Rank
JUN -7073
AXIN1 -6496
SMAD6 -6232
FOS -6217
DROSHA -4907
PMEPA1 -4615
DDX5 -4333
LDLRAD4 -4275
PPM1A -2652
RANBP3 -2194
SMURF1 -9
TRIM33 2051
STUB1 5999

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
JUN -7073
AXIN1 -6496
SMAD6 -6232
FOS -6217
DROSHA -4907
PMEPA1 -4615
DDX5 -4333
LDLRAD4 -4275
PPM1A -2652
RANBP3 -2194
SMURF1 -9
TRIM33 2051
STUB1 5999



GO:0045505 dynein intermediate chain binding
set GO:0045505 dynein intermediate chain binding
setSize 18
pANOVA 0.000978
s.dist 0.449
p.adjustANOVA 0.0851


Top enriched genes
Top 20 genes
GeneID Gene Rank
DNAH10 7032
DNAH7 6802
FRRS1L 6615
DNAH8 6447
HTT 6347
DYNC1H1 6291
HOOK3 5882
DYNC2H1 4986
DNAH3 4516
DNAH9 2854
DYNLL2 1845
DNAAF5 1577
DYNLT3 1438
DYL1 535
DNAH17 408
DYNLRB1 -310
DNAH12 -915
DYNLT1 -3104

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DNAH10 7032
DNAH7 6802
FRRS1L 6615
DNAH8 6447
HTT 6347
DYNC1H1 6291
HOOK3 5882
DYNC2H1 4986
DNAH3 4516
DNAH9 2854
DYNLL2 1845
DNAAF5 1577
DYNLT3 1438
DYL1 535
DNAH17 408
DYNLRB1 -310
DNAH12 -915
DYNLT1 -3104



GO:0051382 kinetochore assembly
set GO:0051382 kinetochore assembly
setSize 11
pANOVA 0.0106
s.dist -0.445
p.adjustANOVA 0.256


Top enriched genes
Top 20 genes
GeneID Gene Rank
CENPC -6556
DLGAP5 -5358
CENPH -5213
MIS12 -4034
CENPE -3598
CENPX -3454
CENPT -3326
CENPK -1427
SUGT1 -1150
POGZ -713
CENPW 685

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All member genes
GeneID Gene Rank
CENPC -6556
DLGAP5 -5358
CENPH -5213
MIS12 -4034
CENPE -3598
CENPX -3454
CENPT -3326
CENPK -1427
SUGT1 -1150
POGZ -713
CENPW 685



GO:0003735 structural constituent of ribosome
set GO:0003735 structural constituent of ribosome
setSize 118
pANOVA 1.96e-16
s.dist -0.438
p.adjustANOVA 3.46e-13


Top enriched genes
Top 20 genes
GeneID Gene Rank
MRPL17 -7080
RPS28 -7063
MRPS21 -7036
MRPL16 -6935
MRPL20 -6889
RPS20 -6887
MRPL14 -6864
RPS13 -6863
RPS15A -6840
RPL13 -6792
MRPL2 -6701
MRPL51 -6666
MRPS15 -6637
RPL15 -6620
RPL37 -6536
RPS26 -6503
MRPL12 -6477
RPL37A -6459
RPL23A -6416
RPS6 -6381

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MRPL17 -7080
RPS28 -7063
MRPS21 -7036
MRPL16 -6935
MRPL20 -6889
RPS20 -6887
MRPL14 -6864
RPS13 -6863
RPS15A -6840
RPL13 -6792
MRPL2 -6701
MRPL51 -6666
MRPS15 -6637
RPL15 -6620
RPL37 -6536
RPS26 -6503
MRPL12 -6477
RPL37A -6459
RPL23A -6416
RPS6 -6381
RPS15 -6374
RPL6 -6360
RPL26L1 -6347
RPS2 -6304
RPS14 -6281
MRPL36 -6218
RPL11 -6067
MRPL37 -6044
RPL10A -6007
RPL19 -5987
RPL9 -5963
RPS8 -5837
MRPS30 -5794
RPL30 -5752
RPL38 -5584
RPS27A -5565
MRPL49 -5519
MRPS18A -5512
RPL3L -5330
RPL14 -5299
RPL34 -5190
RPL5 -5117
DDA1 -5048
MRPL24 -5044
MRPS23 -5040
MRPL28 -5015
RPL23 -4952
RPL21 -4641
RPS4Y1 -4635
RPS12 -4619
MRPS16 -4537
RPS7 -4477
RPL7 -4428
MRPS12 -4326
RPL31 -4281
RPL3 -4221
RPL12 -3798
MRPS11 -3746
RPS3 -3707
RPL27A -3700
RPS11 -3610
MRPS6 -3591
RPS16 -3498
MRPS31 -3352
RPS24 -3282
RPL32 -3253
MRPS17 -3135
MRPS9 -3123
DAP3 -3022
MRPL23 -2992
RPL36 -2938
RPL18A -2818
RPL35 -2634
RPS21 -2512
RPL35A -2410
RPS10 -2393
MRPL13 -1955
RPS3A -1918
RPL29 -1913
MRPS5 -1836
SRBD1 -1790
RPL22 -1611
RPLP2 -1510
RPLP0 -1405
RPL27 -1386
RPLP1 -1306
MRPL41 -1168
MRPL3 -1146
RPL7L1 -1124
MRPL27 -1103
RPS17 -888
MRPS35 -705
RPL4 -647
RPL8 -600
MRPL15 -483
RPL22L1 -381
MRPL18 39
RPL24 86
MRPL21 559
MRPS2 588
MRPL19 774
RPS23 931
MRPL47 945
UBA52 1485
MRPL35 1732
RPS29 2161
MRPS22 2338
MRPL10 2398
MRPL32 2749
MRPS34 3018
MRPL46 3571
MRPS25 3698
MRPS14 4611
MRPS18C 4865
RPS27L 4973
MRPL22 5313
MRPS10 5680
MRPS7 6114



GO:0031032 actomyosin structure organization
set GO:0031032 actomyosin structure organization
setSize 17
pANOVA 0.00186
s.dist 0.436
p.adjustANOVA 0.118


Top enriched genes
Top 20 genes
GeneID Gene Rank
CDC42BPA 7151
MYH10 7135
MYH9 7058
MYH11 6701
EPB41L3 6477
LMO7 5235
CNN2 5137
CNN3 3401
EPB41L1 3392
ROCK1 3320
CDC42BPB 2778
EPB41L5 2287
EPB41L2 557
EPB41 -226
EPB41L4A -556
ROCK2 -990
MYL6 -4466

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CDC42BPA 7151
MYH10 7135
MYH9 7058
MYH11 6701
EPB41L3 6477
LMO7 5235
CNN2 5137
CNN3 3401
EPB41L1 3392
ROCK1 3320
CDC42BPB 2778
EPB41L5 2287
EPB41L2 557
EPB41 -226
EPB41L4A -556
ROCK2 -990
MYL6 -4466



GO:0006412 translation
set GO:0006412 translation
setSize 96
pANOVA 4.49e-13
s.dist -0.428
p.adjustANOVA 3.95e-10


Top enriched genes
Top 20 genes
GeneID Gene Rank
MRPL17 -7080
MRPS21 -7036
MRPL16 -6935
MRPL20 -6889
RPS20 -6887
MRPL14 -6864
RPS13 -6863
RPS15A -6840
RPL13 -6792
MRPL2 -6701
MRPL51 -6666
MRPS15 -6637
RPL37 -6536
MRPL12 -6477
RPL37A -6459
RPL23A -6416
RPS15 -6374
RPL26L1 -6347
GUF1 -6315
RPS2 -6304

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All member genes
GeneID Gene Rank
MRPL17 -7080
MRPS21 -7036
MRPL16 -6935
MRPL20 -6889
RPS20 -6887
MRPL14 -6864
RPS13 -6863
RPS15A -6840
RPL13 -6792
MRPL2 -6701
MRPL51 -6666
MRPS15 -6637
RPL37 -6536
MRPL12 -6477
RPL37A -6459
RPL23A -6416
RPS15 -6374
RPL26L1 -6347
GUF1 -6315
RPS2 -6304
RPS14 -6281
MRPL36 -6218
RPL11 -6067
MRPL37 -6044
RPL19 -5987
RPS8 -5837
MRPS30 -5794
RPS27A -5565
MRPL49 -5519
MRPS18A -5512
RPL3L -5330
RPL14 -5299
RPL34 -5190
RPL5 -5117
DDA1 -5048
MRPL24 -5044
MRPS23 -5040
RPL23 -4952
RPL21 -4641
RPS4Y1 -4635
MRPS16 -4537
RPS7 -4477
MRPS12 -4326
RPL3 -4221
RPL12 -3798
MRPS11 -3746
RPS3 -3707
RPL27A -3700
C2H6orf52 -3650
RPS11 -3610
MRPS6 -3591
GSPT2 -3585
RPS16 -3498
RPS24 -3282
RPL32 -3253
MRPS17 -3135
MRPS9 -3123
RPL35 -2634
RPS21 -2512
RPL35A -2410
MRPL33 -2238
TRNAU1AP -2094
MRPL13 -1955
RPS3A -1918
MRPS5 -1836
SRBD1 -1790
RPL22 -1611
RPL27 -1386
HBS1L -1180
MRPL41 -1168
MRPL3 -1146
CPEB4 -1112
MRPL27 -1103
RPS17 -888
RPL4 -647
MRPL15 -483
RPL22L1 -381
MRPL18 39
EIF2AK2 327
MRPS2 588
MRPL19 774
RPS23 931
MRPL47 945
UBA52 1485
MRPL35 1732
EIF4ENIF1 2022
RPS29 2161
MRPL10 2398
MRPL32 2749
CPEB3 4087
MRPS14 4611
MRPS18C 4865
RPS27L 4973
MRPL22 5313
MRPS10 5680
MRPS7 6114



GO:0006623 protein targeting to vacuole
set GO:0006623 protein targeting to vacuole
setSize 11
pANOVA 0.0159
s.dist 0.42
p.adjustANOVA 0.292


Top enriched genes
Top 20 genes
GeneID Gene Rank
VPS13A 7043
PIK3R4 6606
VPS13C 6098
VPS8 5908
VPS13D 5838
VPS37B 5629
GID4 3540
VPS41 3203
VPS37A 1312
MON1A -5417
VPS37C -5830

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All member genes
GeneID Gene Rank
VPS13A 7043
PIK3R4 6606
VPS13C 6098
VPS8 5908
VPS13D 5838
VPS37B 5629
GID4 3540
VPS41 3203
VPS37A 1312
MON1A -5417
VPS37C -5830



GO:0071007 U2-type catalytic step 2 spliceosome
set GO:0071007 U2-type catalytic step 2 spliceosome
setSize 24
pANOVA 0.000384
s.dist -0.419
p.adjustANOVA 0.067


Top enriched genes
Top 20 genes
GeneID Gene Rank
SNRPA1 -7079
SNRPD1 -6665
SNRNP40 -6259
SNW1 -6098
PPIE -5841
SNRPGP15 -5585
PPIL1 -5243
CRNKL1 -4499
CWC22 -4353
SNRPF -4315
PLRG1 -3951
PRPF19 -3930
BUD31 -3730
CWC15 -3721
CDC40 -3484
SYF2 -2995
BCAS2 -2057
SNRPD2 -1440
EFTUD2 -469
RBM22 -8

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All member genes
GeneID Gene Rank
SNRPA1 -7079
SNRPD1 -6665
SNRNP40 -6259
SNW1 -6098
PPIE -5841
SNRPGP15 -5585
PPIL1 -5243
CRNKL1 -4499
CWC22 -4353
SNRPF -4315
PLRG1 -3951
PRPF19 -3930
BUD31 -3730
CWC15 -3721
CDC40 -3484
SYF2 -2995
BCAS2 -2057
SNRPD2 -1440
EFTUD2 -469
RBM22 -8
SNRPE 679
SNRPB2 1993
DHX8 2277
PRPF8 6818



GO:0048278 vesicle docking
set GO:0048278 vesicle docking
setSize 13
pANOVA 0.00939
s.dist -0.416
p.adjustANOVA 0.243


Top enriched genes
Top 20 genes
GeneID Gene Rank
STX7 -6914
CEP83 -6758
STX16 -5645
CAV2 -5119
NDRG4 -3373
STX1A -3346
STX3 -3188
TSNARE1 -2736
STX17 -2520
STX12 -1395
STX19 23
STX11 1458
STX2 1837

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
STX7 -6914
CEP83 -6758
STX16 -5645
CAV2 -5119
NDRG4 -3373
STX1A -3346
STX3 -3188
TSNARE1 -2736
STX17 -2520
STX12 -1395
STX19 23
STX11 1458
STX2 1837



GO:2000773 negative regulation of cellular senescence
set GO:2000773 negative regulation of cellular senescence
setSize 12
pANOVA 0.0131
s.dist -0.414
p.adjustANOVA 0.273


Top enriched genes
Top 20 genes
GeneID Gene Rank
TWIST1 -7026
YBX1 -7016
BCL6 -6735
SIRT6 -6100
FZR1 -5984
TBX2 -4983
AKT3 -3779
PLK2 -45
FBXO5 428
SIRT1 1480
MIF 2473
RBL1 2711

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TWIST1 -7026
YBX1 -7016
BCL6 -6735
SIRT6 -6100
FZR1 -5984
TBX2 -4983
AKT3 -3779
PLK2 -45
FBXO5 428
SIRT1 1480
MIF 2473
RBL1 2711



GO:0005828 kinetochore microtubule
set GO:0005828 kinetochore microtubule
setSize 10
pANOVA 0.0238
s.dist -0.413
p.adjustANOVA 0.346


Top enriched genes
Top 20 genes
GeneID Gene Rank
KIF18A -6673
CHMP2A -6260
RAB11A -5961
CHMP4C -4148
CHMP7 -3936
CHMP5 -3467
CHMP2B -2236
CHMP3 -1571
CHMP1B 2272
KNTC1 3226

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
KIF18A -6673
CHMP2A -6260
RAB11A -5961
CHMP4C -4148
CHMP7 -3936
CHMP5 -3467
CHMP2B -2236
CHMP3 -1571
CHMP1B 2272
KNTC1 3226



GO:0005201 extracellular matrix structural constituent
set GO:0005201 extracellular matrix structural constituent
setSize 12
pANOVA 0.014
s.dist 0.41
p.adjustANOVA 0.28


Top enriched genes
Top 20 genes
GeneID Gene Rank
FBN1 7200
FBN2 6864
PXDN 6851
LAMC1 6540
LAMA5 6252
COL5A1 6096
LAMA2 2353
COL4A6 903
ELN 124
LAMA3 -549
COL5A2 -2378
LAMB1 -4100

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FBN1 7200
FBN2 6864
PXDN 6851
LAMC1 6540
LAMA5 6252
COL5A1 6096
LAMA2 2353
COL4A6 903
ELN 124
LAMA3 -549
COL5A2 -2378
LAMB1 -4100



GO:0090443 FAR/SIN/STRIPAK complex
set GO:0090443 FAR/SIN/STRIPAK complex
setSize 12
pANOVA 0.0178
s.dist -0.395
p.adjustANOVA 0.31


Top enriched genes
Top 20 genes
GeneID Gene Rank
PPP2CB -7012
STRIP1 -6957
SIKE1 -6519
STK26 -6276
PDCD10 -5434
MOB4 -4242
PPP2CA -3665
STK25 -1761
CTTNBP2NL -426
STK24 1146
STRN3 1711
STRN 6451

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PPP2CB -7012
STRIP1 -6957
SIKE1 -6519
STK26 -6276
PDCD10 -5434
MOB4 -4242
PPP2CA -3665
STK25 -1761
CTTNBP2NL -426
STK24 1146
STRN3 1711
STRN 6451



GO:0045787 positive regulation of cell cycle
set GO:0045787 positive regulation of cell cycle
setSize 13
pANOVA 0.0148
s.dist -0.39
p.adjustANOVA 0.286


Top enriched genes
Top 20 genes
GeneID Gene Rank
RPS15A -6840
TBX3 -6166
TGFB2 -6161
CALR -5831
RARA -5821
CCPG1 -5496
SLC6A4 -2651
RAD23A -1079
TRIM32 -955
FOXG1 -546
ZPR1 290
PROX1 628
LRP6 5354

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -6840
TBX3 -6166
TGFB2 -6161
CALR -5831
RARA -5821
CCPG1 -5496
SLC6A4 -2651
RAD23A -1079
TRIM32 -955
FOXG1 -546
ZPR1 290
PROX1 628
LRP6 5354



GO:0061631 ubiquitin conjugating enzyme activity
set GO:0061631 ubiquitin conjugating enzyme activity
setSize 24
pANOVA 0.000954
s.dist -0.39
p.adjustANOVA 0.0851


Top enriched genes
Top 20 genes
GeneID Gene Rank
UBE2B -6625
UBE2E1 -6603
UBE2G2 -6457
UBE2L3 -6442
UBE2Z -5483
UBE2D3 -5444
UBE2J2 -4997
UBE2O -4834
UBE2T -4297
UBE2J1 -4224
AKTIP -4200
UBE2H -3931
UBE2Q1 -3789
UBE2E3 -2841
UBE2G1 -2275
UBE2D1 -2050
UBE2A -1743
UBE2R2 -1520
UBE2N -909
UBE2K 484

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All member genes
GeneID Gene Rank
UBE2B -6625
UBE2E1 -6603
UBE2G2 -6457
UBE2L3 -6442
UBE2Z -5483
UBE2D3 -5444
UBE2J2 -4997
UBE2O -4834
UBE2T -4297
UBE2J1 -4224
AKTIP -4200
UBE2H -3931
UBE2Q1 -3789
UBE2E3 -2841
UBE2G1 -2275
UBE2D1 -2050
UBE2A -1743
UBE2R2 -1520
UBE2N -909
UBE2K 484
UBE2QL1 1873
CDC34 2408
UBE2D2 2757
BIRC6 6189



GO:0030946 protein tyrosine phosphatase activity, metal-dependent
set GO:0030946 protein tyrosine phosphatase activity, metal-dependent
setSize 15
pANOVA 0.00904
s.dist 0.389
p.adjustANOVA 0.238


Top enriched genes
Top 20 genes
GeneID Gene Rank
PTPRS 6906
PTPN14 6865
EPM2A 6596
PTPN1 6486
PTPN21 6167
DUSP4 5317
PTPRG 5191
EYA3 4435
DUSP7 4265
PTPRJ 1990
DUSP14 256
PTPN11 -11
DUSP5 -2356
DUSP12 -3223
PGP -5893

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All member genes
GeneID Gene Rank
PTPRS 6906
PTPN14 6865
EPM2A 6596
PTPN1 6486
PTPN21 6167
DUSP4 5317
PTPRG 5191
EYA3 4435
DUSP7 4265
PTPRJ 1990
DUSP14 256
PTPN11 -11
DUSP5 -2356
DUSP12 -3223
PGP -5893



GO:0140793 histone H2AXY142 phosphatase activity
set GO:0140793 histone H2AXY142 phosphatase activity
setSize 15
pANOVA 0.00904
s.dist 0.389
p.adjustANOVA 0.238


Top enriched genes
Top 20 genes
GeneID Gene Rank
PTPRS 6906
PTPN14 6865
EPM2A 6596
PTPN1 6486
PTPN21 6167
DUSP4 5317
PTPRG 5191
EYA3 4435
DUSP7 4265
PTPRJ 1990
DUSP14 256
PTPN11 -11
DUSP5 -2356
DUSP12 -3223
PGP -5893

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All member genes
GeneID Gene Rank
PTPRS 6906
PTPN14 6865
EPM2A 6596
PTPN1 6486
PTPN21 6167
DUSP4 5317
PTPRG 5191
EYA3 4435
DUSP7 4265
PTPRJ 1990
DUSP14 256
PTPN11 -11
DUSP5 -2356
DUSP12 -3223
PGP -5893



GO:0036121 double-stranded DNA helicase activity
set GO:0036121 double-stranded DNA helicase activity
setSize 11
pANOVA 0.0258
s.dist 0.388
p.adjustANOVA 0.359


Top enriched genes
Top 20 genes
GeneID Gene Rank
CHD7 6853
MCM9 6269
IGHMBP2 6117
MCM3 5156
ERCC3 4250
UPF1 4131
CHD1 3370
MCM8 2504
BLM -1460
MCM5 -2029
TWNK -3712

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CHD7 6853
MCM9 6269
IGHMBP2 6117
MCM3 5156
ERCC3 4250
UPF1 4131
CHD1 3370
MCM8 2504
BLM -1460
MCM5 -2029
TWNK -3712



GO:0006744 ubiquinone biosynthetic process
set GO:0006744 ubiquinone biosynthetic process
setSize 11
pANOVA 0.027
s.dist -0.385
p.adjustANOVA 0.359


Top enriched genes
Top 20 genes
GeneID Gene Rank
RTN4IP1 -6591
COQ3 -6275
PDSS1 -5891
NDUFA9 -5348
COQ6 -4852
COQ9 -4478
PDSS2 -2719
COQ5 -1021
COQ7 -827
COQ4 2029
COQ8A 6536

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RTN4IP1 -6591
COQ3 -6275
PDSS1 -5891
NDUFA9 -5348
COQ6 -4852
COQ9 -4478
PDSS2 -2719
COQ5 -1021
COQ7 -827
COQ4 2029
COQ8A 6536



GO:0051959 dynein light intermediate chain binding
set GO:0051959 dynein light intermediate chain binding
setSize 17
pANOVA 0.00602
s.dist 0.385
p.adjustANOVA 0.194


Top enriched genes
Top 20 genes
GeneID Gene Rank
DNAH10 7032
DNAH7 6802
DNAH8 6447
DYNC1H1 6291
CCDC88A 6140
HOOK3 5882
DYNC2H1 4986
DNAH3 4516
HOOK1 4493
DNAH9 2854
RAB11FIP3 2479
DNAH17 408
BICD2 346
DNAH12 -915
RILP -1629
RILPL1 -2000
RAB11A -5961

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All member genes
GeneID Gene Rank
DNAH10 7032
DNAH7 6802
DNAH8 6447
DYNC1H1 6291
CCDC88A 6140
HOOK3 5882
DYNC2H1 4986
DNAH3 4516
HOOK1 4493
DNAH9 2854
RAB11FIP3 2479
DNAH17 408
BICD2 346
DNAH12 -915
RILP -1629
RILPL1 -2000
RAB11A -5961



GO:0008139 nuclear localization sequence binding
set GO:0008139 nuclear localization sequence binding
setSize 13
pANOVA 0.0165
s.dist 0.384
p.adjustANOVA 0.294


Top enriched genes
Top 20 genes
GeneID Gene Rank
TNPO1 7114
NUP214 7107
KPNB1 6985
NUP153 6464
NUP98 5829
KPNA1 5442
IPO5 4926
KPNA5 4232
KPNA3 1980
NUP58 1123
KPNA4 -2928
KPNA2 -5627
KPNA6 -5865

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TNPO1 7114
NUP214 7107
KPNB1 6985
NUP153 6464
NUP98 5829
KPNA1 5442
IPO5 4926
KPNA5 4232
KPNA3 1980
NUP58 1123
KPNA4 -2928
KPNA2 -5627
KPNA6 -5865



GO:0048513 animal organ development
set GO:0048513 animal organ development
setSize 11
pANOVA 0.0281
s.dist -0.382
p.adjustANOVA 0.359


Top enriched genes
Top 20 genes
GeneID Gene Rank
TGFB2 -6161
RAI2 -6141
SPRY1 -5808
INHBB -5401
SPRY2 -4855
FXR1 -4492
SPRY4 -4301
EDA -3470
SOBP 1713
SPRY3 4782
FMR1 4898

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TGFB2 -6161
RAI2 -6141
SPRY1 -5808
INHBB -5401
SPRY2 -4855
FXR1 -4492
SPRY4 -4301
EDA -3470
SOBP 1713
SPRY3 4782
FMR1 4898



GO:0043029 T cell homeostasis
set GO:0043029 T cell homeostasis
setSize 13
pANOVA 0.0184
s.dist 0.378
p.adjustANOVA 0.317


Top enriched genes
Top 20 genes
GeneID Gene Rank
RC3H1 6868
PPP3CB 6741
RC3H2 6603
CASP3 5531
NCKAP1L 4863
TCIRG1 4603
CHST3 4249
PPP2R3C 1915
FADD 926
SLC39A3 776
LGALS2 -163
IL7R -3074
PPP2CA -3665

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RC3H1 6868
PPP3CB 6741
RC3H2 6603
CASP3 5531
NCKAP1L 4863
TCIRG1 4603
CHST3 4249
PPP2R3C 1915
FADD 926
SLC39A3 776
LGALS2 -163
IL7R -3074
PPP2CA -3665



GO:0051453 regulation of intracellular pH
set GO:0051453 regulation of intracellular pH
setSize 14
pANOVA 0.0152
s.dist -0.375
p.adjustANOVA 0.286


Top enriched genes
Top 20 genes
GeneID Gene Rank
SLC4A2 -7002
SLC4A3 -6652
SLC9A9 -6384
ATP5B -5630
CHP1 -5070
SLC9A5 -4696
SLC9A7 -3819
TM9SF4 -1416
SLC4A7 -1001
SLC4A10 -435
SLC9A6 -338
HVCN1 132
SLC4A4 1799
SLC9A8 4092

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SLC4A2 -7002
SLC4A3 -6652
SLC9A9 -6384
ATP5B -5630
CHP1 -5070
SLC9A5 -4696
SLC9A7 -3819
TM9SF4 -1416
SLC4A7 -1001
SLC4A10 -435
SLC9A6 -338
HVCN1 132
SLC4A4 1799
SLC9A8 4092



GO:0001782 B cell homeostasis
set GO:0001782 B cell homeostasis
setSize 12
pANOVA 0.025
s.dist 0.374
p.adjustANOVA 0.354


Top enriched genes
Top 20 genes
GeneID Gene Rank
RC3H1 6868
BCL2 6639
RC3H2 6603
SOS2 6238
CASP3 5531
NCKAP1L 4863
SOS1 4205
PPP2R3C 1915
BBS4 -210
LYN -690
IL7R -3074
CAMLG -5823

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RC3H1 6868
BCL2 6639
RC3H2 6603
SOS2 6238
CASP3 5531
NCKAP1L 4863
SOS1 4205
PPP2R3C 1915
BBS4 -210
LYN -690
IL7R -3074
CAMLG -5823



GO:0001657 ureteric bud development
set GO:0001657 ureteric bud development
setSize 14
pANOVA 0.0161
s.dist -0.371
p.adjustANOVA 0.293


Top enriched genes
Top 20 genes
GeneID Gene Rank
FGFR1 -6279
SMAD6 -6232
SLIT2 -5897
GDF11 -5887
RARA -5821
SPRY1 -5808
RET -5509
OSR1 -3940
BMPER -646
SIM1 -605
SFRP1 -157
CRLF1 579
ARG2 4549
SMAD5 5560

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FGFR1 -6279
SMAD6 -6232
SLIT2 -5897
GDF11 -5887
RARA -5821
SPRY1 -5808
RET -5509
OSR1 -3940
BMPER -646
SIM1 -605
SFRP1 -157
CRLF1 579
ARG2 4549
SMAD5 5560



GO:0032526 response to retinoic acid
set GO:0032526 response to retinoic acid
setSize 15
pANOVA 0.0135
s.dist -0.368
p.adjustANOVA 0.273


Top enriched genes
Top 20 genes
GeneID Gene Rank
DNAAF2 -7025
RARA -5821
GDAP2 -5504
CTSH -5316
GATA6 -5253
TBX2 -4983
PITX2 -4373
ISL2 -3449
RXRA -2889
BCO1 -1721
TIE1 -807
RARB 11
ALDH1A2 1875
ACER2 3354
ASXL1 3547

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DNAAF2 -7025
RARA -5821
GDAP2 -5504
CTSH -5316
GATA6 -5253
TBX2 -4983
PITX2 -4373
ISL2 -3449
RXRA -2889
BCO1 -1721
TIE1 -807
RARB 11
ALDH1A2 1875
ACER2 3354
ASXL1 3547



GO:0048008 platelet-derived growth factor receptor signaling pathway
set GO:0048008 platelet-derived growth factor receptor signaling pathway
setSize 17
pANOVA 0.00885
s.dist 0.367
p.adjustANOVA 0.238


Top enriched genes
Top 20 genes
GeneID Gene Rank
CSPG4 7052
PLEKHA1 7010
NRP1 6315
PDGFD 6200
CSRNP1 5857
SMPD3 5309
RAPGEF1 4502
SGPL1 3943
ITGB3 3727
NR4A3 3456
PLAT 2154
PTPRJ 1990
PDGFA 1031
FER -784
BCAR1 -2756
MYO1E -3345
TIPARP -5692

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CSPG4 7052
PLEKHA1 7010
NRP1 6315
PDGFD 6200
CSRNP1 5857
SMPD3 5309
RAPGEF1 4502
SGPL1 3943
ITGB3 3727
NR4A3 3456
PLAT 2154
PTPRJ 1990
PDGFA 1031
FER -784
BCAR1 -2756
MYO1E -3345
TIPARP -5692



GO:0009925 basal plasma membrane
set GO:0009925 basal plasma membrane
setSize 11
pANOVA 0.0355
s.dist 0.366
p.adjustANOVA 0.381


Top enriched genes
Top 20 genes
GeneID Gene Rank
OSCP1 6298
SLCO3A1 5666
SLC22A4 5648
ERBB2 5580
ERBB4 5469
MYO1C 4930
LDLRAP1 4001
EGFR 1441
MET -754
SLC12A2 -1930
SLC22A5 -6634

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OSCP1 6298
SLCO3A1 5666
SLC22A4 5648
ERBB2 5580
ERBB4 5469
MYO1C 4930
LDLRAP1 4001
EGFR 1441
MET -754
SLC12A2 -1930
SLC22A5 -6634



GO:0007076 mitotic chromosome condensation
set GO:0007076 mitotic chromosome condensation
setSize 10
pANOVA 0.0451
s.dist -0.366
p.adjustANOVA 0.431


Top enriched genes
Top 20 genes
GeneID Gene Rank
NUSAP1 -6886
NCAPD2 -6588
SMC2 -6358
NCAPH2 -3513
NCAPG -3330
NCAPH -1698
SMC4 -1631
AKAP8L 297
NCAPD3 1972
PHF13 2340

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All member genes
GeneID Gene Rank
NUSAP1 -6886
NCAPD2 -6588
SMC2 -6358
NCAPH2 -3513
NCAPG -3330
NCAPH -1698
SMC4 -1631
AKAP8L 297
NCAPD3 1972
PHF13 2340



GO:0090201 negative regulation of release of cytochrome c from mitochondria
set GO:0090201 negative regulation of release of cytochrome c from mitochondria
setSize 11
pANOVA 0.0357
s.dist -0.366
p.adjustANOVA 0.381


Top enriched genes
Top 20 genes
GeneID Gene Rank
PSMD10 -6484
HGF -6402
GPX1 -6235
TRIAP1 -5726
FXN -1829
GHITM -1757
PARL -1253
PPIF -982
BAK1 -529
PRELID1 -362
OPA1 3635

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PSMD10 -6484
HGF -6402
GPX1 -6235
TRIAP1 -5726
FXN -1829
GHITM -1757
PARL -1253
PPIF -982
BAK1 -529
PRELID1 -362
OPA1 3635



GO:0050770 regulation of axonogenesis
set GO:0050770 regulation of axonogenesis
setSize 13
pANOVA 0.0227
s.dist 0.365
p.adjustANOVA 0.342


Top enriched genes
Top 20 genes
GeneID Gene Rank
EPHA4 6862
PAK3 6780
SIPA1L1 6777
EPHB3 5427
PAK2 5330
KIF13B 4285
PAK1 4196
RUFY3 3587
POU3F2 3158
UST 965
LRRC4C -214
RET -5509
CHN1 -6642

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
EPHA4 6862
PAK3 6780
SIPA1L1 6777
EPHB3 5427
PAK2 5330
KIF13B 4285
PAK1 4196
RUFY3 3587
POU3F2 3158
UST 965
LRRC4C -214
RET -5509
CHN1 -6642



GO:0035925 mRNA 3’-UTR AU-rich region binding
set GO:0035925 mRNA 3’-UTR AU-rich region binding
setSize 13
pANOVA 0.0228
s.dist -0.365
p.adjustANOVA 0.342


Top enriched genes
Top 20 genes
GeneID Gene Rank
EXOSC8 -7070
EXOSC9 -6831
ELAVL1 -5768
TIA1 -5749
FXR1 -4492
MEX3D -3536
ZFP36L2 -3379
DHX36 -2958
NUDT21 -1576
EXOSC7 -409
ZC3H12A 947
ARID5A 3151
RBMS3 4766

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
EXOSC8 -7070
EXOSC9 -6831
ELAVL1 -5768
TIA1 -5749
FXR1 -4492
MEX3D -3536
ZFP36L2 -3379
DHX36 -2958
NUDT21 -1576
EXOSC7 -409
ZC3H12A 947
ARID5A 3151
RBMS3 4766



Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.4.2 (2024-10-31)
## Platform: x86_64-pc-linux-gnu
## Running under: Ubuntu 24.04.1 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.12.0 
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.12.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Australia/Melbourne
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] stats4    stats     graphics  grDevices utils     datasets  methods  
## [8] base     
## 
## other attached packages:
##  [1] pkgload_1.4.0               GGally_2.2.1               
##  [3] ggplot2_3.5.1               gtools_3.9.5               
##  [5] tibble_3.2.1                echarts4r_0.4.5            
##  [7] UpSetR_1.4.0                beeswarm_0.4.0             
##  [9] kableExtra_1.4.0            eulerr_7.0.2               
## [11] mitch_1.19.2                MASS_7.3-61                
## [13] gplots_3.2.0                DESeq2_1.44.0              
## [15] SummarizedExperiment_1.34.0 Biobase_2.64.0             
## [17] MatrixGenerics_1.16.0       matrixStats_1.4.1          
## [19] GenomicRanges_1.56.1        GenomeInfoDb_1.40.1        
## [21] IRanges_2.38.1              S4Vectors_0.42.1           
## [23] BiocGenerics_0.50.0         reshape2_1.4.4             
## [25] dplyr_1.1.4                 zoo_1.8-12                 
## 
## loaded via a namespace (and not attached):
##  [1] tidyselect_1.2.1        viridisLite_0.4.2       farver_2.1.2           
##  [4] bitops_1.0-9            fastmap_1.2.0           promises_1.3.2         
##  [7] digest_0.6.37           mime_0.12               lifecycle_1.0.4        
## [10] polylabelr_0.3.0        magrittr_2.0.3          compiler_4.4.2         
## [13] rlang_1.1.4             sass_0.4.9              tools_4.4.2            
## [16] yaml_2.3.10             knitr_1.49              labeling_0.4.3         
## [19] S4Arrays_1.4.1          htmlwidgets_1.6.4       DelayedArray_0.30.1    
## [22] xml2_1.3.6              plyr_1.8.9              RColorBrewer_1.1-3     
## [25] abind_1.4-8             BiocParallel_1.38.0     KernSmooth_2.23-24     
## [28] withr_3.0.2             purrr_1.0.2             polyclip_1.10-7        
## [31] grid_4.4.2              caTools_1.18.3          xtable_1.8-4           
## [34] colorspace_2.1-1        scales_1.3.0            cli_3.6.3              
## [37] rmarkdown_2.29          crayon_1.5.3            generics_0.1.3         
## [40] rstudioapi_0.17.1       httr_1.4.7              cachem_1.1.0           
## [43] stringr_1.5.1           zlibbioc_1.50.0         parallel_4.4.2         
## [46] XVector_0.44.0          vctrs_0.6.5             Matrix_1.7-1           
## [49] jsonlite_1.8.9          systemfonts_1.1.0       locfit_1.5-9.10        
## [52] jquerylib_0.1.4         tidyr_1.3.1             glue_1.8.0             
## [55] ggstats_0.7.0           codetools_0.2-20        stringi_1.8.4          
## [58] gtable_0.3.6            later_1.4.1             UCSC.utils_1.0.0       
## [61] munsell_0.5.1           pillar_1.10.0           htmltools_0.5.8.1      
## [64] GenomeInfoDbData_1.2.12 R6_2.5.1                evaluate_1.0.1         
## [67] shiny_1.10.0            lattice_0.22-6          httpuv_1.6.15          
## [70] bslib_0.8.0             Rcpp_1.0.13-1           svglite_2.1.3          
## [73] gridExtra_2.3           SparseArray_1.4.8       xfun_0.49              
## [76] pkgconfig_2.0.3

END of report