Mitch Report

date generated: 2025-01-14

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch

	stat
5_8S_rRNA	1.0783442
A4GALT	-2.3287576
AAAS	0.4658765
AACS	2.9719878
AADAC	-0.7056949
AADAT	-1.1764787

Here are some metrics about the input data profile:

Profiling data metrics

	Profile metrics
num_genesets	5133
num_genes_in_profile	14226
duplicated_genes_present	0
num_profile_genes_in_sets	9146
num_profile_genes_not_in_sets	5080

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets:

Gene set metrics

	Gene sets metrics
num_genesets	5133
num_genesets_excluded	3375
num_genesets_included	1758

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

set	setSize	pANOVA	s.dist	p.adjustANOVA
GO:0022625 cytosolic large ribosomal subunit	40	1.11e-22	-0.895	6.53e-20
GO:0002181 cytoplasmic translation	27	4.68e-14	-0.838	6.32e-12
GO:0045116 protein neddylation	10	1.25e-05	-0.798	4.22e-04
GO:0022627 cytosolic small ribosomal subunit	25	9.06e-12	-0.788	8.85e-10
GO:0007076 mitotic chromosome condensation	10	2.24e-05	0.774	6.56e-04
GO:0036121 double-stranded DNA helicase activity	11	2.37e-05	0.736	6.71e-04
GO:0035145 exon-exon junction complex	10	5.88e-05	0.734	1.31e-03
GO:0003735 structural constituent of ribosome	118	8.25e-41	-0.712	1.45e-37
GO:0021915 neural tube development	15	3.23e-06	0.694	1.45e-04
GO:1902774 late endosome to lysosome transport	10	1.44e-04	-0.694	2.76e-03
GO:0000228 nuclear chromosome	13	3.26e-05	0.665	8.18e-04
GO:0070034 telomerase RNA binding	12	8.35e-05	0.656	1.77e-03
GO:0005049 nuclear export signal receptor activity	10	3.75e-04	0.650	5.49e-03
GO:1990518 single-stranded 3’-5’ DNA helicase activity	11	1.98e-04	0.648	3.45e-03
GO:0000793 condensed chromosome	13	5.50e-05	0.646	1.26e-03
GO:2000737 negative regulation of stem cell differentiation	12	1.12e-04	0.644	2.24e-03
GO:0140658 ATP-dependent chromatin remodeler activity	11	2.32e-04	0.641	3.92e-03
GO:0061749 forked DNA-dependent helicase activity	10	4.56e-04	0.640	6.27e-03
GO:1990023 mitotic spindle midzone	10	6.90e-04	0.620	8.54e-03
GO:0017056 structural constituent of nuclear pore	19	5.23e-06	0.604	2.14e-04
GO:0070064 proline-rich region binding	10	9.51e-04	0.604	1.06e-02
GO:0006412 translation	96	3.49e-24	-0.599	3.06e-21
GO:0004364 glutathione transferase activity	10	1.06e-03	-0.598	1.17e-02
GO:0006120 mitochondrial electron transport, NADH to ubiquinone	19	6.85e-06	-0.596	2.56e-04
GO:0071806 protein transmembrane transport	12	3.89e-04	-0.591	5.65e-03
GO:0000380 alternative mRNA splicing, via spliceosome	16	4.58e-05	0.589	1.07e-03
GO:0032585 multivesicular body membrane	12	4.95e-04	-0.581	6.70e-03
GO:0070577 lysine-acetylated histone binding	16	6.19e-05	0.578	1.36e-03
GO:0006337 nucleosome disassembly	10	1.70e-03	0.573	1.73e-02
GO:0000245 spliceosomal complex assembly	10	1.77e-03	0.571	1.77e-02
GO:0003678 DNA helicase activity	20	1.11e-05	0.568	3.90e-04
GO:0016581 NuRD complex	10	2.03e-03	0.563	1.93e-02
GO:0035371 microtubule plus-end	12	9.44e-04	0.551	1.06e-02
GO:0051010 microtubule plus-end binding	11	1.58e-03	0.550	1.64e-02
GO:0007249 canonical NF-kappaB signal transduction	18	5.43e-05	0.550	1.26e-03
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane	18	5.75e-05	-0.548	1.30e-03
GO:0051536 iron-sulfur cluster binding	12	1.10e-03	-0.544	1.20e-02
GO:1990391 DNA repair complex	10	3.19e-03	0.539	2.59e-02
GO:0008233 peptidase activity	10	3.50e-03	-0.533	2.77e-02
GO:0006749 glutathione metabolic process	15	3.65e-04	-0.531	5.40e-03
GO:0045271 respiratory chain complex I	31	3.33e-07	-0.530	1.83e-05
GO:0005840 ribosome	43	2.98e-09	-0.523	2.18e-07
GO:0051315 attachment of mitotic spindle microtubules to kinetochore	10	4.49e-03	0.519	3.23e-02
GO:0016442 RISC complex	11	2.91e-03	0.518	2.45e-02
GO:0035855 megakaryocyte development	10	4.65e-03	0.517	3.31e-02
GO:0003151 outflow tract morphogenesis	19	1.04e-04	0.514	2.13e-03
GO:0032968 positive regulation of transcription elongation by RNA polymerase II	15	5.89e-04	0.513	7.47e-03
GO:0043296 apical junction complex	10	5.21e-03	0.510	3.55e-02
GO:0031468 nuclear membrane reassembly	11	3.58e-03	-0.507	2.82e-02
GO:0031466 Cul5-RING ubiquitin ligase complex	11	3.81e-03	-0.504	2.94e-02

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
GO:0022625 cytosolic large ribosomal subunit	40	1.11e-22	-8.95e-01	6.53e-20
GO:0002181 cytoplasmic translation	27	4.68e-14	-8.38e-01	6.32e-12
GO:0045116 protein neddylation	10	1.25e-05	-7.98e-01	4.22e-04
GO:0022627 cytosolic small ribosomal subunit	25	9.06e-12	-7.88e-01	8.85e-10
GO:0007076 mitotic chromosome condensation	10	2.24e-05	7.74e-01	6.56e-04
GO:0036121 double-stranded DNA helicase activity	11	2.37e-05	7.36e-01	6.71e-04
GO:0035145 exon-exon junction complex	10	5.88e-05	7.34e-01	1.31e-03
GO:0003735 structural constituent of ribosome	118	8.25e-41	-7.12e-01	1.45e-37
GO:0021915 neural tube development	15	3.23e-06	6.94e-01	1.45e-04
GO:1902774 late endosome to lysosome transport	10	1.44e-04	-6.94e-01	2.76e-03
GO:0000228 nuclear chromosome	13	3.26e-05	6.65e-01	8.18e-04
GO:0070034 telomerase RNA binding	12	8.35e-05	6.56e-01	1.77e-03
GO:0005049 nuclear export signal receptor activity	10	3.75e-04	6.50e-01	5.49e-03
GO:1990518 single-stranded 3’-5’ DNA helicase activity	11	1.98e-04	6.48e-01	3.45e-03
GO:0000793 condensed chromosome	13	5.50e-05	6.46e-01	1.26e-03
GO:2000737 negative regulation of stem cell differentiation	12	1.12e-04	6.44e-01	2.24e-03
GO:0140658 ATP-dependent chromatin remodeler activity	11	2.32e-04	6.41e-01	3.92e-03
GO:0061749 forked DNA-dependent helicase activity	10	4.56e-04	6.40e-01	6.27e-03
GO:1990023 mitotic spindle midzone	10	6.90e-04	6.20e-01	8.54e-03
GO:0017056 structural constituent of nuclear pore	19	5.23e-06	6.04e-01	2.14e-04
GO:0070064 proline-rich region binding	10	9.51e-04	6.04e-01	1.06e-02
GO:0006412 translation	96	3.49e-24	-5.99e-01	3.06e-21
GO:0004364 glutathione transferase activity	10	1.06e-03	-5.98e-01	1.17e-02
GO:0006120 mitochondrial electron transport, NADH to ubiquinone	19	6.85e-06	-5.96e-01	2.56e-04
GO:0071806 protein transmembrane transport	12	3.89e-04	-5.91e-01	5.65e-03
GO:0000380 alternative mRNA splicing, via spliceosome	16	4.58e-05	5.89e-01	1.07e-03
GO:0032585 multivesicular body membrane	12	4.95e-04	-5.81e-01	6.70e-03
GO:0070577 lysine-acetylated histone binding	16	6.19e-05	5.78e-01	1.36e-03
GO:0006337 nucleosome disassembly	10	1.70e-03	5.73e-01	1.73e-02
GO:0000245 spliceosomal complex assembly	10	1.77e-03	5.71e-01	1.77e-02
GO:0003678 DNA helicase activity	20	1.11e-05	5.68e-01	3.90e-04
GO:0016581 NuRD complex	10	2.03e-03	5.63e-01	1.93e-02
GO:0035371 microtubule plus-end	12	9.44e-04	5.51e-01	1.06e-02
GO:0051010 microtubule plus-end binding	11	1.58e-03	5.50e-01	1.64e-02
GO:0007249 canonical NF-kappaB signal transduction	18	5.43e-05	5.50e-01	1.26e-03
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane	18	5.75e-05	-5.48e-01	1.30e-03
GO:0051536 iron-sulfur cluster binding	12	1.10e-03	-5.44e-01	1.20e-02
GO:1990391 DNA repair complex	10	3.19e-03	5.39e-01	2.59e-02
GO:0008233 peptidase activity	10	3.50e-03	-5.33e-01	2.77e-02
GO:0006749 glutathione metabolic process	15	3.65e-04	-5.31e-01	5.40e-03
GO:0045271 respiratory chain complex I	31	3.33e-07	-5.30e-01	1.83e-05
GO:0005840 ribosome	43	2.98e-09	-5.23e-01	2.18e-07
GO:0051315 attachment of mitotic spindle microtubules to kinetochore	10	4.49e-03	5.19e-01	3.23e-02
GO:0016442 RISC complex	11	2.91e-03	5.18e-01	2.45e-02
GO:0035855 megakaryocyte development	10	4.65e-03	5.17e-01	3.31e-02
GO:0003151 outflow tract morphogenesis	19	1.04e-04	5.14e-01	2.13e-03
GO:0032968 positive regulation of transcription elongation by RNA polymerase II	15	5.89e-04	5.13e-01	7.47e-03
GO:0043296 apical junction complex	10	5.21e-03	5.10e-01	3.55e-02
GO:0031468 nuclear membrane reassembly	11	3.58e-03	-5.07e-01	2.82e-02
GO:0031466 Cul5-RING ubiquitin ligase complex	11	3.81e-03	-5.04e-01	2.94e-02
GO:0001578 microtubule bundle formation	15	8.76e-04	4.96e-01	1.01e-02
GO:0007042 lysosomal lumen acidification	10	6.70e-03	-4.95e-01	4.30e-02
GO:0016226 iron-sulfur cluster assembly	17	4.10e-04	-4.95e-01	5.85e-03
GO:0007026 negative regulation of microtubule depolymerization	17	4.13e-04	4.95e-01	5.85e-03
GO:0003777 microtubule motor activity	23	4.24e-05	4.93e-01	1.01e-03
GO:0071816 tail-anchored membrane protein insertion into ER membrane	10	6.94e-03	-4.93e-01	4.39e-02
GO:0003148 outflow tract septum morphogenesis	12	3.16e-03	4.92e-01	2.59e-02
GO:1900181 negative regulation of protein localization to nucleus	11	4.95e-03	4.89e-01	3.42e-02
GO:0051537 2 iron, 2 sulfur cluster binding	17	5.44e-04	-4.84e-01	7.14e-03
GO:0004857 enzyme inhibitor activity	12	3.70e-03	4.84e-01	2.89e-02
GO:0030331 nuclear estrogen receptor binding	19	2.76e-04	4.82e-01	4.43e-03
GO:0006334 nucleosome assembly	27	1.51e-05	4.81e-01	4.73e-04
GO:0005763 mitochondrial small ribosomal subunit	21	1.38e-04	-4.80e-01	2.70e-03
GO:0035278 miRNA-mediated gene silencing by inhibition of translation	12	4.02e-03	4.80e-01	3.01e-02
GO:0042277 peptide binding	10	8.69e-03	4.79e-01	5.08e-02
GO:0000987 cis-regulatory region sequence-specific DNA binding	21	1.47e-04	4.79e-01	2.78e-03
GO:0005484 SNAP receptor activity	26	2.43e-05	-4.78e-01	6.77e-04
GO:0015035 protein-disulfide reductase activity	14	2.01e-03	-4.77e-01	1.92e-02
GO:0051881 regulation of mitochondrial membrane potential	15	1.42e-03	-4.76e-01	1.48e-02
GO:0033962 P-body assembly	14	2.09e-03	4.75e-01	1.95e-02
GO:2000648 positive regulation of stem cell proliferation	12	4.54e-03	4.73e-01	3.24e-02
GO:0034727 piecemeal microautophagy of the nucleus	13	3.18e-03	-4.73e-01	2.59e-02
GO:0050905 neuromuscular process	10	9.78e-03	-4.72e-01	5.39e-02
GO:0032981 mitochondrial respiratory chain complex I assembly	38	5.20e-07	-4.71e-01	2.77e-05
GO:0048041 focal adhesion assembly	14	2.33e-03	4.70e-01	2.07e-02
GO:0007097 nuclear migration	15	1.82e-03	4.65e-01	1.80e-02
GO:0070182 DNA polymerase binding	13	3.73e-03	4.65e-01	2.90e-02
GO:0008137 NADH dehydrogenase (ubiquinone) activity	10	1.14e-02	-4.62e-01	6.07e-02
GO:0048010 vascular endothelial growth factor receptor signaling pathway	13	3.97e-03	4.61e-01	3.01e-02
GO:0060045 positive regulation of cardiac muscle cell proliferation	13	4.47e-03	4.55e-01	3.23e-02
GO:0006906 vesicle fusion	15	2.31e-03	-4.54e-01	2.06e-02
GO:0002040 sprouting angiogenesis	18	9.02e-04	4.52e-01	1.03e-02
GO:0060236 regulation of mitotic spindle organization	12	6.76e-03	4.52e-01	4.31e-02
GO:0031201 SNARE complex	33	7.74e-06	-4.50e-01	2.84e-04
GO:0034314 Arp2/3 complex-mediated actin nucleation	11	9.79e-03	-4.50e-01	5.39e-02
GO:1990247 N6-methyladenosine-containing RNA reader activity	10	1.39e-02	4.49e-01	7.02e-02
GO:2001222 regulation of neuron migration	10	1.42e-02	4.48e-01	7.16e-02
GO:0005871 kinesin complex	22	2.82e-04	4.47e-01	4.43e-03
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	15	2.75e-03	4.47e-01	2.35e-02
GO:0061631 ubiquitin conjugating enzyme activity	24	1.55e-04	-4.46e-01	2.86e-03
GO:0006346 DNA methylation-dependent constitutive heterochromatin formation	10	1.52e-02	4.43e-01	7.53e-02
GO:0140416 transcription regulator inhibitor activity	12	8.23e-03	4.41e-01	4.91e-02
GO:0009378 four-way junction helicase activity	13	6.08e-03	4.40e-01	3.96e-02
GO:0033617 mitochondrial cytochrome c oxidase assembly	13	7.24e-03	-4.30e-01	4.55e-02
GO:0140588 chromatin looping	27	1.11e-04	4.30e-01	2.24e-03
GO:0038061 non-canonical NF-kappaB signal transduction	11	1.36e-02	4.30e-01	6.96e-02
GO:0002102 podosome	17	2.41e-03	4.25e-01	2.11e-02
GO:0051480 regulation of cytosolic calcium ion concentration	13	8.10e-03	-4.24e-01	4.90e-02
GO:0140693 molecular condensate scaffold activity	24	3.42e-04	4.22e-01	5.13e-03
GO:0051603 proteolysis involved in protein catabolic process	23	4.55e-04	-4.22e-01	6.27e-03
GO:0016180 snRNA processing	10	2.17e-02	4.19e-01	9.47e-02
GO:0060349 bone morphogenesis	12	1.22e-02	4.18e-01	6.34e-02
GO:0097602 cullin family protein binding	16	3.83e-03	-4.18e-01	2.94e-02
GO:0035329 hippo signaling	17	2.90e-03	4.17e-01	2.45e-02
GO:0045815 transcription initiation-coupled chromatin remodeling	20	1.26e-03	4.17e-01	1.34e-02
GO:0010592 positive regulation of lamellipodium assembly	10	2.27e-02	4.16e-01	9.82e-02
GO:0007492 endoderm development	10	2.27e-02	4.16e-01	9.82e-02
GO:0097718 disordered domain specific binding	15	5.40e-03	4.15e-01	3.64e-02
GO:0001046 core promoter sequence-specific DNA binding	11	1.73e-02	4.14e-01	8.18e-02
GO:0031929 TOR signaling	13	9.75e-03	-4.14e-01	5.39e-02
GO:0140584 chromatin extrusion motor activity	23	5.95e-04	4.14e-01	7.47e-03
GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity	23	5.95e-04	4.14e-01	7.47e-03
GO:0140849 ATP-dependent H2AZ histone chaperone activity	23	5.95e-04	4.14e-01	7.47e-03
GO:0035613 RNA stem-loop binding	11	1.82e-02	4.11e-01	8.54e-02
GO:0005762 mitochondrial large ribosomal subunit	38	1.28e-05	-4.09e-01	4.25e-04
GO:0030150 protein import into mitochondrial matrix	12	1.45e-02	-4.08e-01	7.27e-02
GO:0061775 cohesin loader activity	24	5.48e-04	4.08e-01	7.14e-03
GO:0048873 homeostasis of number of cells within a tissue	14	8.55e-03	4.06e-01	5.03e-02
GO:0002218 activation of innate immune response	17	4.06e-03	4.03e-01	3.01e-02
GO:0052689 carboxylic ester hydrolase activity	11	2.11e-02	-4.02e-01	9.34e-02
GO:1902894 negative regulation of miRNA transcription	12	1.62e-02	4.01e-01	7.80e-02
GO:0006351 DNA-templated transcription	36	3.14e-05	4.01e-01	8.00e-04
GO:0030992 intraciliary transport particle B	15	7.32e-03	-4.00e-01	4.58e-02
GO:0046907 intracellular transport	14	9.66e-03	-4.00e-01	5.37e-02
GO:1903077 negative regulation of protein localization to plasma membrane	14	9.83e-03	-3.99e-01	5.40e-02
GO:0031526 brush border membrane	12	1.72e-02	3.97e-01	8.15e-02
GO:0006488 dolichol-linked oligosaccharide biosynthetic process	14	1.01e-02	-3.97e-01	5.52e-02
GO:0010976 positive regulation of neuron projection development	28	2.81e-04	3.97e-01	4.43e-03
GO:0070403 NAD+ binding	11	2.28e-02	-3.97e-01	9.82e-02
GO:0061709 reticulophagy	15	7.85e-03	-3.96e-01	4.79e-02
GO:0016363 nuclear matrix	46	3.33e-06	3.96e-01	1.46e-04
GO:0031252 cell leading edge	19	2.88e-03	3.95e-01	2.45e-02
GO:0070530 K63-linked polyubiquitin modification-dependent protein binding	17	4.89e-03	3.94e-01	3.41e-02
GO:0071168 protein localization to chromatin	17	4.91e-03	3.94e-01	3.41e-02
GO:0120163 negative regulation of cold-induced thermogenesis	22	1.39e-03	3.94e-01	1.47e-02
GO:0060379 cardiac muscle cell myoblast differentiation	10	3.14e-02	3.93e-01	1.25e-01
GO:0051019 mitogen-activated protein kinase binding	11	2.40e-02	3.93e-01	1.02e-01
GO:0070888 E-box binding	21	1.93e-03	3.91e-01	1.89e-02
GO:0031490 chromatin DNA binding	40	1.98e-05	3.90e-01	5.91e-04
GO:0005758 mitochondrial intermembrane space	47	3.88e-06	-3.89e-01	1.66e-04
GO:0005828 kinetochore microtubule	10	3.30e-02	-3.89e-01	1.29e-01
GO:0030900 forebrain development	20	2.60e-03	3.89e-01	2.24e-02
GO:0007416 synapse assembly	24	9.74e-04	3.89e-01	1.08e-02
GO:0050808 synapse organization	17	5.55e-03	3.89e-01	3.72e-02
GO:0000422 autophagy of mitochondrion	14	1.20e-02	-3.88e-01	6.25e-02
GO:0005782 peroxisomal matrix	10	3.44e-02	-3.86e-01	1.33e-01
GO:0003281 ventricular septum development	15	9.61e-03	3.86e-01	5.37e-02
GO:0106222 lncRNA binding	17	6.08e-03	3.84e-01	3.96e-02
GO:0006913 nucleocytoplasmic transport	18	4.89e-03	3.83e-01	3.41e-02
GO:0005743 mitochondrial inner membrane	180	9.48e-19	-3.82e-01	2.78e-16
GO:0050661 NADP binding	15	1.08e-02	-3.80e-01	5.80e-02
GO:0045454 cell redox homeostasis	20	3.27e-03	-3.80e-01	2.63e-02
GO:0001708 cell fate specification	12	2.27e-02	3.80e-01	9.82e-02
GO:0006635 fatty acid beta-oxidation	26	8.18e-04	-3.79e-01	9.65e-03
GO:0030513 positive regulation of BMP signaling pathway	19	4.23e-03	3.79e-01	3.10e-02
GO:0032508 DNA duplex unwinding	44	1.44e-05	3.78e-01	4.59e-04
GO:0048278 vesicle docking	13	1.83e-02	-3.78e-01	8.54e-02
GO:0003724 RNA helicase activity	37	7.10e-05	3.78e-01	1.54e-03
GO:0016235 aggresome	16	9.17e-03	3.76e-01	5.27e-02
GO:0071222 cellular response to lipopolysaccharide	46	1.07e-05	3.75e-01	3.84e-04
GO:0048015 phosphatidylinositol-mediated signaling	17	7.47e-03	3.75e-01	4.66e-02
GO:0046961 proton-transporting ATPase activity, rotational mechanism	14	1.53e-02	-3.75e-01	7.53e-02
GO:0070498 interleukin-1-mediated signaling pathway	11	3.22e-02	-3.73e-01	1.27e-01
GO:0002039 p53 binding	44	1.89e-05	3.73e-01	5.74e-04
GO:0005882 intermediate filament	20	4.13e-03	3.71e-01	3.05e-02
GO:0045292 mRNA cis splicing, via spliceosome	13	2.09e-02	3.70e-01	9.31e-02
GO:0016514 SWI/SNF complex	20	4.20e-03	3.70e-01	3.09e-02
GO:0001570 vasculogenesis	26	1.14e-03	3.69e-01	1.23e-02
GO:0098869 cellular oxidant detoxification	28	7.55e-04	-3.68e-01	9.09e-03
GO:0000281 mitotic cytokinesis	34	2.08e-04	3.68e-01	3.58e-03
GO:0048026 positive regulation of mRNA splicing, via spliceosome	12	2.78e-02	3.67e-01	1.13e-01
GO:0043627 response to estrogen	10	4.46e-02	3.67e-01	1.59e-01
GO:0050772 positive regulation of axonogenesis	12	2.82e-02	3.66e-01	1.14e-01
GO:0150052 regulation of postsynapse assembly	12	2.91e-02	3.64e-01	1.17e-01
GO:0071889 14-3-3 protein binding	15	1.48e-02	3.64e-01	7.36e-02
GO:0022604 regulation of cell morphogenesis	14	1.87e-02	3.63e-01	8.54e-02
GO:0006260 DNA replication	34	2.57e-04	3.62e-01	4.22e-03
GO:0001221 transcription coregulator binding	16	1.21e-02	3.62e-01	6.33e-02
GO:0042393 histone binding	94	1.39e-09	3.62e-01	1.06e-07
GO:0004435 phosphatidylinositol phospholipase C activity	11	3.80e-02	3.61e-01	1.43e-01
GO:0032206 positive regulation of telomere maintenance	14	1.93e-02	3.61e-01	8.76e-02
GO:0002053 positive regulation of mesenchymal cell proliferation	11	3.89e-02	3.60e-01	1.45e-01
GO:1900182 positive regulation of protein localization to nucleus	25	1.95e-03	3.58e-01	1.90e-02
GO:0046966 nuclear thyroid hormone receptor binding	15	1.67e-02	3.57e-01	8.03e-02
GO:0051290 protein heterotetramerization	10	5.09e-02	3.57e-01	1.76e-01
GO:0071108 protein K48-linked deubiquitination	15	1.70e-02	3.56e-01	8.12e-02
GO:0006695 cholesterol biosynthetic process	16	1.37e-02	3.56e-01	7.00e-02
GO:0045943 positive regulation of transcription by RNA polymerase I	11	4.12e-02	3.56e-01	1.51e-01
GO:0008320 protein transmembrane transporter activity	11	4.17e-02	-3.55e-01	1.51e-01
GO:0004386 helicase activity	40	1.20e-04	3.52e-01	2.36e-03
GO:0003682 chromatin binding	237	1.43e-20	3.51e-01	6.09e-18
GO:0007095 mitotic G2 DNA damage checkpoint signaling	30	8.82e-04	3.51e-01	1.01e-02
GO:0048812 neuron projection morphogenesis	29	1.08e-03	3.51e-01	1.19e-02
GO:0000381 regulation of alternative mRNA splicing, via spliceosome	31	7.33e-04	3.51e-01	8.95e-03
GO:0051393 alpha-actinin binding	10	5.55e-02	3.50e-01	1.84e-01
GO:0009888 tissue development	18	1.03e-02	3.49e-01	5.61e-02
GO:0000045 autophagosome assembly	52	1.35e-05	-3.49e-01	4.40e-04
GO:0005518 collagen binding	35	3.61e-04	-3.49e-01	5.38e-03
GO:0030020 extracellular matrix structural constituent conferring tensile strength	16	1.59e-02	-3.48e-01	7.75e-02
GO:0031507 heterochromatin formation	27	1.74e-03	3.48e-01	1.75e-02
GO:0035979 histone H2AXS139 kinase activity	32	7.22e-04	3.45e-01	8.87e-03
GO:0051028 mRNA transport	27	1.92e-03	3.45e-01	1.89e-02
GO:0003689 DNA clamp loader activity	32	7.43e-04	3.45e-01	9.01e-03
GO:0061484 hematopoietic stem cell homeostasis	12	3.89e-02	3.44e-01	1.45e-01
GO:0006396 RNA processing	21	6.35e-03	3.44e-01	4.12e-02
GO:1990841 promoter-specific chromatin binding	34	5.19e-04	3.44e-01	6.87e-03
GO:0043409 negative regulation of MAPK cascade	20	7.76e-03	3.44e-01	4.77e-02
GO:0071013 catalytic step 2 spliceosome	52	1.81e-05	3.44e-01	5.58e-04
GO:0005721 pericentric heterochromatin	18	1.17e-02	3.43e-01	6.17e-02
GO:0042100 B cell proliferation	14	2.63e-02	3.43e-01	1.09e-01
GO:0032720 negative regulation of tumor necrosis factor production	18	1.18e-02	3.43e-01	6.20e-02
GO:0045669 positive regulation of osteoblast differentiation	37	3.11e-04	3.43e-01	4.76e-03
GO:0004602 glutathione peroxidase activity	12	4.01e-02	-3.42e-01	1.48e-01
GO:0000794 condensed nuclear chromosome	20	8.18e-03	3.42e-01	4.91e-02
GO:0019843 rRNA binding	22	5.64e-03	-3.41e-01	3.76e-02
GO:0032467 positive regulation of cytokinesis	14	2.76e-02	3.40e-01	1.13e-01
GO:0008033 tRNA processing	15	2.26e-02	-3.40e-01	9.82e-02
GO:0070085 glycosylation	14	2.77e-02	-3.40e-01	1.13e-01
GO:0001618 virus receptor activity	10	6.29e-02	3.40e-01	2.02e-01
GO:0072518 Rho-dependent protein serine/threonine kinase activity	32	9.04e-04	3.39e-01	1.03e-02
GO:1990244 histone H2AT120 kinase activity	31	1.14e-03	3.38e-01	1.23e-02
GO:0097431 mitotic spindle pole	27	2.41e-03	3.38e-01	2.11e-02
GO:0021987 cerebral cortex development	24	4.27e-03	3.37e-01	3.11e-02
GO:0004676 3-phosphoinositide-dependent protein kinase activity	31	1.20e-03	3.36e-01	1.29e-02
GO:0031491 nucleosome binding	25	3.65e-03	3.36e-01	2.86e-02
GO:0002230 positive regulation of defense response to virus by host	11	5.45e-02	3.35e-01	1.83e-01
GO:0003725 double-stranded RNA binding	43	1.49e-04	3.34e-01	2.79e-03
GO:0045666 positive regulation of neuron differentiation	26	3.20e-03	3.34e-01	2.59e-02
GO:0050839 cell adhesion molecule binding	21	8.18e-03	3.33e-01	4.91e-02
GO:0042813 Wnt receptor activity	12	4.56e-02	3.33e-01	1.61e-01
GO:0007017 microtubule-based process	11	5.60e-02	-3.33e-01	1.85e-01
GO:0017053 transcription repressor complex	34	8.25e-04	3.31e-01	9.66e-03
GO:0007018 microtubule-based movement	40	3.07e-04	3.30e-01	4.73e-03
GO:1905564 positive regulation of vascular endothelial cell proliferation	10	7.26e-02	3.28e-01	2.24e-01
GO:0006641 triglyceride metabolic process	10	7.31e-02	-3.27e-01	2.24e-01
GO:0005667 transcription regulator complex	90	8.40e-08	3.27e-01	5.28e-06
GO:0060038 cardiac muscle cell proliferation	12	5.00e-02	3.27e-01	1.75e-01
GO:0008139 nuclear localization sequence binding	13	4.14e-02	3.27e-01	1.51e-01
GO:0007259 cell surface receptor signaling pathway via JAK-STAT	21	9.59e-03	3.27e-01	5.37e-02
GO:0008094 ATP-dependent activity, acting on DNA	11	6.09e-02	3.26e-01	1.97e-01
GO:0004677 DNA-dependent protein kinase activity	31	1.67e-03	3.26e-01	1.72e-02
GO:0010718 positive regulation of epithelial to mesenchymal transition	26	4.04e-03	3.26e-01	3.01e-02
GO:0035175 histone H3S10 kinase activity	31	1.71e-03	3.26e-01	1.73e-02
GO:0072354 histone H3T3 kinase activity	31	1.71e-03	3.26e-01	1.73e-02
GO:0030133 transport vesicle	23	6.94e-03	-3.25e-01	4.39e-02
GO:0005771 multivesicular body	21	1.02e-02	-3.24e-01	5.58e-02
GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	12	5.22e-02	3.24e-01	1.79e-01
GO:0035402 histone H3T11 kinase activity	30	2.18e-03	3.23e-01	1.95e-02
GO:0044022 histone H3S28 kinase activity	30	2.18e-03	3.23e-01	1.95e-02
GO:0044023 histone H4S1 kinase activity	30	2.18e-03	3.23e-01	1.95e-02
GO:0044024 histone H2AS1 kinase activity	30	2.18e-03	3.23e-01	1.95e-02
GO:0044025 histone H2BS14 kinase activity	30	2.18e-03	3.23e-01	1.95e-02
GO:0072371 histone H2AS121 kinase activity	30	2.18e-03	3.23e-01	1.95e-02
GO:0140855 histone H3S57 kinase activity	30	2.18e-03	3.23e-01	1.95e-02
GO:0140857 histone H3T45 kinase activity	30	2.18e-03	3.23e-01	1.95e-02
GO:0098686 hippocampal mossy fiber to CA3 synapse	18	1.76e-02	-3.23e-01	8.29e-02
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	21	1.04e-02	3.23e-01	5.62e-02
GO:0050767 regulation of neurogenesis	14	3.69e-02	3.22e-01	1.40e-01
GO:0030276 clathrin binding	17	2.15e-02	3.22e-01	9.44e-02
GO:0003713 transcription coactivator activity	127	3.87e-10	3.22e-01	3.09e-08
GO:0005044 scavenger receptor activity	10	7.83e-02	-3.22e-01	2.34e-01
GO:0031902 late endosome membrane	67	5.56e-06	-3.21e-01	2.22e-04
GO:0006879 intracellular iron ion homeostasis	31	1.99e-03	-3.21e-01	1.91e-02
GO:0030057 desmosome	12	5.48e-02	3.20e-01	1.83e-01
GO:0010494 cytoplasmic stress granule	58	2.59e-05	3.20e-01	7.11e-04
GO:0009792 embryo development ending in birth or egg hatching	10	8.08e-02	3.19e-01	2.36e-01
GO:0000792 heterochromatin	19	1.70e-02	3.16e-01	8.12e-02
GO:2000042 negative regulation of double-strand break repair via homologous recombination	16	2.85e-02	3.16e-01	1.16e-01
GO:0030330 DNA damage response, signal transduction by p53 class mediator	12	5.80e-02	3.16e-01	1.90e-01
GO:0050829 defense response to Gram-negative bacterium	12	5.82e-02	3.16e-01	1.90e-01
GO:0006406 mRNA export from nucleus	28	3.83e-03	3.16e-01	2.94e-02
GO:0034237 protein kinase A regulatory subunit binding	14	4.09e-02	3.16e-01	1.50e-01
GO:0030855 epithelial cell differentiation	29	3.32e-03	-3.15e-01	2.65e-02
GO:0030866 cortical actin cytoskeleton organization	20	1.47e-02	3.15e-01	7.36e-02
GO:0043536 positive regulation of blood vessel endothelial cell migration	18	2.08e-02	3.15e-01	9.26e-02
GO:0030216 keratinocyte differentiation	28	3.97e-03	3.15e-01	3.01e-02
GO:0051560 mitochondrial calcium ion homeostasis	13	5.02e-02	-3.14e-01	1.75e-01
GO:0003714 transcription corepressor activity	101	5.46e-08	3.13e-01	3.59e-06
GO:0097038 perinuclear endoplasmic reticulum	10	8.65e-02	-3.13e-01	2.46e-01
GO:0019827 stem cell population maintenance	21	1.31e-02	3.13e-01	6.70e-02
GO:1902600 proton transmembrane transport	59	3.47e-05	-3.12e-01	8.59e-04
GO:0045773 positive regulation of axon extension	10	8.84e-02	3.11e-01	2.50e-01
GO:0006979 response to oxidative stress	50	1.44e-04	-3.11e-01	2.76e-03
GO:0046488 phosphatidylinositol metabolic process	12	6.29e-02	3.10e-01	2.02e-01
GO:0000956 nuclear-transcribed mRNA catabolic process	12	6.34e-02	3.10e-01	2.03e-01
GO:0050673 epithelial cell proliferation	19	1.97e-02	3.09e-01	8.92e-02
GO:0000791 euchromatin	29	4.00e-03	3.09e-01	3.01e-02
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors	18	2.35e-02	3.08e-01	1.00e-01
GO:0050850 positive regulation of calcium-mediated signaling	10	9.18e-02	3.08e-01	2.58e-01
GO:0007010 cytoskeleton organization	50	1.75e-04	3.07e-01	3.11e-03
GO:0000786 nucleosome	16	3.36e-02	3.07e-01	1.31e-01
GO:0007417 central nervous system development	40	8.11e-04	3.06e-01	9.63e-03
GO:0032543 mitochondrial translation	22	1.30e-02	-3.06e-01	6.69e-02
GO:0140823 histone H2BS36 kinase activity	31	3.27e-03	3.05e-01	2.63e-02
GO:0008089 anterograde axonal transport	10	9.54e-02	-3.05e-01	2.64e-01
GO:0043995 histone H4K5 acetyltransferase activity	10	9.57e-02	3.04e-01	2.64e-01
GO:0043996 histone H4K8 acetyltransferase activity	10	9.57e-02	3.04e-01	2.64e-01
GO:1904115 axon cytoplasm	25	8.60e-03	-3.04e-01	5.04e-02
GO:0051056 regulation of small GTPase mediated signal transduction	16	3.55e-02	3.04e-01	1.36e-01
GO:0022626 cytosolic ribosome	13	5.81e-02	3.04e-01	1.90e-01
GO:0034497 protein localization to phagophore assembly site	11	8.15e-02	-3.03e-01	2.37e-01
GO:0031669 cellular response to nutrient levels	12	6.92e-02	3.03e-01	2.16e-01
GO:1903076 regulation of protein localization to plasma membrane	18	2.65e-02	-3.02e-01	1.10e-01
GO:0034142 toll-like receptor 4 signaling pathway	15	4.28e-02	-3.02e-01	1.54e-01
GO:0035615 clathrin adaptor activity	10	9.91e-02	-3.01e-01	2.69e-01
GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity	34	2.38e-03	3.01e-01	2.10e-02
GO:0060047 heart contraction	10	1.00e-01	-3.00e-01	2.72e-01
GO:0072593 reactive oxygen species metabolic process	15	4.43e-02	-3.00e-01	1.58e-01
GO:0097352 autophagosome maturation	23	1.29e-02	-3.00e-01	6.65e-02
GO:0001671 ATPase activator activity	18	2.78e-02	-3.00e-01	1.13e-01
GO:0016446 somatic hypermutation of immunoglobulin genes	10	1.01e-01	2.99e-01	2.73e-01
GO:0009954 proximal/distal pattern formation	14	5.30e-02	2.99e-01	1.80e-01
GO:0022904 respiratory electron transport chain	14	5.30e-02	-2.99e-01	1.80e-01
GO:0035116 embryonic hindlimb morphogenesis	11	8.63e-02	2.99e-01	2.46e-01
GO:0071005 U2-type precatalytic spliceosome	31	4.04e-03	2.98e-01	3.01e-02
GO:0042407 cristae formation	11	8.68e-02	-2.98e-01	2.47e-01
GO:0035064 methylated histone binding	42	8.30e-04	2.98e-01	9.66e-03
GO:0045494 photoreceptor cell maintenance	24	1.15e-02	-2.98e-01	6.08e-02
GO:0043923 positive regulation by host of viral transcription	12	7.43e-02	2.98e-01	2.27e-01
GO:0008143 poly(A) binding	13	6.33e-02	2.97e-01	2.03e-01
GO:0042127 regulation of cell population proliferation	46	4.95e-04	2.97e-01	6.70e-03
GO:0001837 epithelial to mesenchymal transition	17	3.46e-02	2.96e-01	1.33e-01
GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process	14	5.52e-02	2.96e-01	1.84e-01
GO:0005125 cytokine activity	28	6.74e-03	2.96e-01	4.31e-02
GO:0005544 calcium-dependent phospholipid binding	21	1.92e-02	-2.95e-01	8.74e-02
GO:0034614 cellular response to reactive oxygen species	16	4.13e-02	-2.95e-01	1.51e-01
GO:0000785 chromatin	243	3.39e-15	2.94e-01	4.97e-13
GO:0035019 somatic stem cell population maintenance	31	4.70e-03	2.93e-01	3.32e-02
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	12	7.87e-02	-2.93e-01	2.35e-01
GO:0032757 positive regulation of interleukin-8 production	17	3.64e-02	-2.93e-01	1.39e-01
GO:0001917 photoreceptor inner segment	23	1.54e-02	-2.92e-01	7.54e-02
GO:0034045 phagophore assembly site membrane	12	8.00e-02	-2.92e-01	2.35e-01
GO:0005777 peroxisome	49	4.18e-04	-2.91e-01	5.88e-03
GO:0032039 integrator complex	15	5.08e-02	2.91e-01	1.76e-01
GO:0030182 neuron differentiation	56	1.64e-04	2.91e-01	2.97e-03
GO:0048538 thymus development	22	1.81e-02	2.91e-01	8.53e-02
GO:0000118 histone deacetylase complex	22	1.85e-02	2.90e-01	8.54e-02
GO:0042073 intraciliary transport	16	4.46e-02	-2.90e-01	1.59e-01
GO:0045765 regulation of angiogenesis	10	1.13e-01	2.90e-01	2.89e-01
GO:1905168 positive regulation of double-strand break repair via homologous recombination	25	1.23e-02	2.89e-01	6.38e-02
GO:0042789 mRNA transcription by RNA polymerase II	27	9.41e-03	2.89e-01	5.34e-02
GO:0001673 male germ cell nucleus	27	9.47e-03	2.89e-01	5.35e-02
GO:0031124 mRNA 3’-end processing	13	7.17e-02	2.89e-01	2.22e-01
GO:0042981 regulation of apoptotic process	54	2.51e-04	2.88e-01	4.16e-03
GO:0140374 antiviral innate immune response	19	2.99e-02	-2.88e-01	1.20e-01
GO:0043531 ADP binding	20	2.61e-02	2.87e-01	1.09e-01
GO:0001657 ureteric bud development	13	7.32e-02	2.87e-01	2.24e-01
GO:0035403 histone H3T6 kinase activity	32	5.07e-03	2.86e-01	3.47e-02
GO:0004402 histone acetyltransferase activity	11	1.00e-01	2.86e-01	2.72e-01
GO:0008593 regulation of Notch signaling pathway	10	1.18e-01	-2.86e-01	2.97e-01
GO:0031210 phosphatidylcholine binding	18	3.64e-02	-2.85e-01	1.39e-01
GO:0031624 ubiquitin conjugating enzyme binding	17	4.20e-02	-2.85e-01	1.52e-01
GO:0007004 telomere maintenance via telomerase	11	1.02e-01	2.85e-01	2.74e-01
GO:0000242 pericentriolar material	14	6.58e-02	2.84e-01	2.09e-01
GO:0140662 ATP-dependent protein folding chaperone	23	1.85e-02	2.84e-01	8.54e-02
GO:0003712 transcription coregulator activity	75	2.28e-05	2.83e-01	6.57e-04
GO:0046849 bone remodeling	10	1.22e-01	2.83e-01	3.03e-01
GO:0001569 branching involved in blood vessel morphogenesis	15	5.83e-02	2.82e-01	1.90e-01
GO:0006744 ubiquinone biosynthetic process	11	1.05e-01	-2.82e-01	2.77e-01
GO:0004711 ribosomal protein S6 kinase activity	32	5.72e-03	2.82e-01	3.79e-02
GO:0032391 photoreceptor connecting cilium	18	3.89e-02	-2.81e-01	1.45e-01
GO:0032993 protein-DNA complex	21	2.57e-02	2.81e-01	1.08e-01
GO:0005852 eukaryotic translation initiation factor 3 complex	10	1.24e-01	-2.81e-01	3.07e-01
GO:0001894 tissue homeostasis	13	7.96e-02	2.81e-01	2.35e-01
GO:0043488 regulation of mRNA stability	16	5.18e-02	2.81e-01	1.78e-01
GO:0022857 transmembrane transporter activity	37	3.14e-03	-2.81e-01	2.59e-02
GO:0000070 mitotic sister chromatid segregation	18	3.94e-02	2.80e-01	1.46e-01
GO:0097546 ciliary base	17	4.53e-02	-2.80e-01	1.61e-01
GO:0004679 AMP-activated protein kinase activity	32	6.06e-03	2.80e-01	3.96e-02
GO:0042060 wound healing	29	8.98e-03	2.80e-01	5.21e-02
GO:0042273 ribosomal large subunit biogenesis	22	2.28e-02	-2.80e-01	9.82e-02
GO:0044458 motile cilium assembly	12	9.30e-02	-2.80e-01	2.60e-01
GO:0006891 intra-Golgi vesicle-mediated transport	19	3.53e-02	-2.79e-01	1.35e-01
GO:0014704 intercalated disc	14	7.13e-02	2.78e-01	2.21e-01
GO:0030286 dynein complex	10	1.28e-01	-2.78e-01	3.10e-01
GO:0050660 flavin adenine dinucleotide binding	33	5.84e-03	-2.77e-01	3.86e-02
GO:0045214 sarcomere organization	11	1.12e-01	-2.77e-01	2.89e-01
GO:0035198 miRNA binding	20	3.22e-02	2.77e-01	1.27e-01
GO:0006865 amino acid transport	11	1.13e-01	2.76e-01	2.89e-01
GO:0043997 histone H4K12 acetyltransferase activity	10	1.31e-01	2.76e-01	3.16e-01
GO:0015297 antiporter activity	18	4.28e-02	-2.76e-01	1.54e-01
GO:0070161 anchoring junction	16	5.69e-02	2.75e-01	1.88e-01
GO:0003700 DNA-binding transcription factor activity	78	2.74e-05	2.75e-01	7.41e-04
GO:0031116 positive regulation of microtubule polymerization	11	1.15e-01	2.74e-01	2.92e-01
GO:0005815 microtubule organizing center	36	4.51e-03	2.74e-01	3.24e-02
GO:0032266 phosphatidylinositol-3-phosphate binding	32	7.53e-03	-2.73e-01	4.68e-02
GO:0000932 P-body	60	2.79e-04	2.71e-01	4.43e-03
GO:0061025 membrane fusion	21	3.14e-02	-2.71e-01	1.25e-01
GO:0000976 transcription cis-regulatory region binding	54	5.68e-04	2.71e-01	7.34e-03
GO:1902895 positive regulation of miRNA transcription	24	2.16e-02	2.71e-01	9.44e-02
GO:0051302 regulation of cell division	11	1.20e-01	2.71e-01	3.00e-01
GO:0051018 protein kinase A binding	12	1.05e-01	2.71e-01	2.77e-01
GO:0009749 response to glucose	14	7.97e-02	2.71e-01	2.35e-01
GO:0051209 release of sequestered calcium ion into cytosol	19	4.16e-02	2.70e-01	1.51e-01
GO:0042169 SH2 domain binding	20	3.69e-02	2.70e-01	1.40e-01
GO:0042826 histone deacetylase binding	66	1.57e-04	2.69e-01	2.88e-03
GO:0050770 regulation of axonogenesis	13	9.31e-02	2.69e-01	2.60e-01
GO:0001889 liver development	30	1.09e-02	2.69e-01	5.80e-02
GO:0071526 semaphorin-plexin signaling pathway	22	2.97e-02	2.68e-01	1.19e-01
GO:0005977 glycogen metabolic process	14	8.29e-02	-2.68e-01	2.40e-01
GO:0031647 regulation of protein stability	57	5.00e-04	2.67e-01	6.70e-03
GO:0042307 positive regulation of protein import into nucleus	25	2.11e-02	2.66e-01	9.34e-02
GO:0045665 negative regulation of neuron differentiation	24	2.40e-02	2.66e-01	1.02e-01
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific	345	2.43e-17	2.66e-01	5.33e-15
GO:0090303 positive regulation of wound healing	11	1.28e-01	-2.65e-01	3.10e-01
GO:0005978 glycogen biosynthetic process	11	1.29e-01	-2.65e-01	3.11e-01
GO:0006631 fatty acid metabolic process	34	7.61e-03	-2.65e-01	4.70e-02
GO:0015485 cholesterol binding	29	1.38e-02	-2.64e-01	7.02e-02
GO:1903543 positive regulation of exosomal secretion	10	1.50e-01	-2.63e-01	3.48e-01
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator	11	1.32e-01	2.63e-01	3.17e-01
GO:0098761 cellular response to interleukin-7	10	1.50e-01	2.63e-01	3.49e-01
GO:0006974 DNA damage response	120	7.02e-07	2.62e-01	3.52e-05
GO:0060412 ventricular septum morphogenesis	18	5.40e-02	2.62e-01	1.82e-01
GO:0030134 COPII-coated ER to Golgi transport vesicle	21	3.77e-02	-2.62e-01	1.42e-01
GO:0032922 circadian regulation of gene expression	34	8.24e-03	2.62e-01	4.91e-02
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	32	1.04e-02	-2.62e-01	5.62e-02
GO:0043138 3’-5’ DNA helicase activity	10	1.53e-01	2.61e-01	3.50e-01
GO:0010575 positive regulation of vascular endothelial growth factor production	13	1.04e-01	2.61e-01	2.76e-01
GO:0043024 ribosomal small subunit binding	13	1.04e-01	2.61e-01	2.76e-01
GO:0000460 maturation of 5.8S rRNA	11	1.35e-01	-2.61e-01	3.22e-01
GO:0033290 eukaryotic 48S preinitiation complex	13	1.04e-01	-2.61e-01	2.76e-01
GO:0015459 potassium channel regulator activity	12	1.18e-01	-2.60e-01	2.97e-01
GO:0005912 adherens junction	69	1.86e-04	2.60e-01	3.27e-03
GO:0051491 positive regulation of filopodium assembly	14	9.22e-02	2.60e-01	2.59e-01
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	67	2.36e-04	-2.60e-01	3.95e-03
GO:0038066 p38MAPK cascade	12	1.19e-01	2.60e-01	2.99e-01
GO:0006338 chromatin remodeling	249	1.87e-12	2.60e-01	2.19e-10
GO:0019003 GDP binding	44	2.91e-03	-2.60e-01	2.45e-02
GO:0005764 lysosome	132	2.71e-07	-2.60e-01	1.54e-05
GO:0045165 cell fate commitment	21	3.98e-02	2.59e-01	1.47e-01
GO:0000407 phagophore assembly site	20	4.49e-02	-2.59e-01	1.60e-01
GO:0016607 nuclear speck	240	5.68e-12	2.59e-01	5.88e-10
GO:0061952 midbody abscission	14	9.49e-02	-2.58e-01	2.63e-01
GO:0031663 lipopolysaccharide-mediated signaling pathway	11	1.39e-01	-2.58e-01	3.30e-01
GO:0015914 phospholipid transport	26	2.31e-02	-2.57e-01	9.89e-02
GO:0071560 cellular response to transforming growth factor beta stimulus	16	7.49e-02	2.57e-01	2.28e-01
GO:0000421 autophagosome membrane	23	3.32e-02	-2.57e-01	1.29e-01
GO:0045599 negative regulation of fat cell differentiation	21	4.20e-02	2.56e-01	1.52e-01
GO:0030177 positive regulation of Wnt signaling pathway	17	6.75e-02	2.56e-01	2.12e-01
GO:0005540 hyaluronic acid binding	14	9.72e-02	2.56e-01	2.67e-01
GO:0045595 regulation of cell differentiation	13	1.10e-01	2.56e-01	2.88e-01
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding	391	5.24e-18	2.56e-01	1.32e-15
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules	36	7.98e-03	2.56e-01	4.84e-02
GO:0035023 regulation of Rho protein signal transduction	16	7.73e-02	2.55e-01	2.32e-01
GO:0030514 negative regulation of BMP signaling pathway	26	2.44e-02	2.55e-01	1.03e-01
GO:0010824 regulation of centrosome duplication	15	8.78e-02	-2.55e-01	2.49e-01
GO:0030426 growth cone	41	4.86e-03	2.54e-01	3.41e-02
GO:0003824 catalytic activity	10	1.65e-01	-2.53e-01	3.66e-01
GO:0008584 male gonad development	28	2.04e-02	2.53e-01	9.14e-02
GO:0004693 cyclin-dependent protein serine/threonine kinase activity	10	1.66e-01	2.53e-01	3.66e-01
GO:0042162 telomeric DNA binding	20	5.04e-02	2.53e-01	1.75e-01
GO:0050768 negative regulation of neurogenesis	10	1.67e-01	2.52e-01	3.69e-01
GO:0010719 negative regulation of epithelial to mesenchymal transition	16	8.14e-02	2.52e-01	2.37e-01
GO:0006099 tricarboxylic acid cycle	19	5.80e-02	-2.51e-01	1.90e-01
GO:0008327 methyl-CpG binding	16	8.21e-02	2.51e-01	2.39e-01
GO:0051233 spindle midzone	17	7.36e-02	2.51e-01	2.25e-01
GO:0072089 stem cell proliferation	21	4.70e-02	2.50e-01	1.65e-01
GO:0072686 mitotic spindle	70	2.94e-04	2.50e-01	4.58e-03
GO:0001756 somitogenesis	24	3.40e-02	2.50e-01	1.32e-01
GO:0030863 cortical cytoskeleton	10	1.72e-01	-2.50e-01	3.76e-01
GO:0001732 formation of cytoplasmic translation initiation complex	12	1.34e-01	-2.50e-01	3.22e-01
GO:0006487 protein N-linked glycosylation	29	2.14e-02	-2.47e-01	9.40e-02
GO:0032728 positive regulation of interferon-beta production	15	9.88e-02	2.46e-01	2.69e-01
GO:0030139 endocytic vesicle	37	9.59e-03	2.46e-01	5.37e-02
GO:0003333 amino acid transmembrane transport	10	1.78e-01	2.46e-01	3.84e-01
GO:0016491 oxidoreductase activity	46	3.94e-03	-2.46e-01	3.01e-02
GO:0001726 ruffle	43	5.31e-03	2.46e-01	3.61e-02
GO:0030897 HOPS complex	10	1.79e-01	-2.46e-01	3.85e-01
GO:0003697 single-stranded DNA binding	67	5.17e-04	2.45e-01	6.87e-03
GO:0060216 definitive hemopoiesis	10	1.80e-01	2.45e-01	3.88e-01
GO:0050890 cognition	18	7.24e-02	2.45e-01	2.23e-01
GO:0001664 G protein-coupled receptor binding	22	4.73e-02	2.44e-01	1.66e-01
GO:0010314 phosphatidylinositol-5-phosphate binding	11	1.62e-01	-2.44e-01	3.63e-01
GO:0006355 regulation of DNA-templated transcription	158	1.45e-07	2.43e-01	8.81e-06
GO:0045648 positive regulation of erythrocyte differentiation	18	7.48e-02	2.43e-01	2.28e-01
GO:0045995 regulation of embryonic development	27	2.93e-02	2.42e-01	1.18e-01
GO:0004715 non-membrane spanning protein tyrosine kinase activity	20	6.06e-02	2.42e-01	1.97e-01
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT	13	1.31e-01	2.42e-01	3.16e-01
GO:0070840 dynein complex binding	11	1.65e-01	2.42e-01	3.66e-01
GO:0007405 neuroblast proliferation	21	5.51e-02	2.42e-01	1.84e-01
GO:0055074 calcium ion homeostasis	18	7.62e-02	-2.41e-01	2.30e-01
GO:0097110 scaffold protein binding	28	2.71e-02	2.41e-01	1.12e-01
GO:0008654 phospholipid biosynthetic process	12	1.48e-01	-2.41e-01	3.45e-01
GO:0045190 isotype switching	13	1.32e-01	2.41e-01	3.17e-01
GO:0014009 glial cell proliferation	10	1.87e-01	2.41e-01	3.96e-01
GO:0030864 cortical actin cytoskeleton	32	1.85e-02	2.41e-01	8.54e-02
GO:0017022 myosin binding	11	1.67e-01	2.41e-01	3.69e-01
GO:0000122 negative regulation of transcription by RNA polymerase II	395	3.13e-16	2.40e-01	5.50e-14
GO:0016192 vesicle-mediated transport	101	3.06e-05	-2.40e-01	7.92e-04
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific	112	1.16e-05	2.40e-01	3.99e-04
GO:0048675 axon extension	15	1.07e-01	2.40e-01	2.83e-01
GO:0070373 negative regulation of ERK1 and ERK2 cascade	30	2.32e-02	2.40e-01	9.89e-02
GO:0016829 lyase activity	15	1.08e-01	-2.40e-01	2.84e-01
GO:0001750 photoreceptor outer segment	23	4.71e-02	-2.39e-01	1.66e-01
GO:0003677 DNA binding	335	6.37e-14	2.39e-01	7.99e-12
GO:0003887 DNA-directed DNA polymerase activity	16	9.78e-02	2.39e-01	2.68e-01
GO:0003729 mRNA binding	146	6.44e-07	2.39e-01	3.33e-05
GO:0007601 visual perception	38	1.09e-02	-2.39e-01	5.80e-02
GO:0007052 mitotic spindle organization	34	1.60e-02	2.39e-01	7.77e-02
GO:0048255 mRNA stabilization	16	9.84e-02	2.39e-01	2.69e-01
GO:0061512 protein localization to cilium	22	5.28e-02	-2.39e-01	1.80e-01
GO:0048839 inner ear development	12	1.53e-01	2.38e-01	3.50e-01
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	13	1.37e-01	2.38e-01	3.27e-01
GO:0048477 oogenesis	14	1.23e-01	2.38e-01	3.05e-01
GO:0032465 regulation of cytokinesis	23	4.83e-02	2.38e-01	1.69e-01
GO:0140672 ATAC complex	11	1.72e-01	2.38e-01	3.77e-01
GO:0016791 phosphatase activity	15	1.12e-01	-2.37e-01	2.89e-01
GO:0001675 acrosome assembly	11	1.73e-01	-2.37e-01	3.78e-01
GO:0000781 chromosome, telomeric region	75	3.93e-04	2.37e-01	5.67e-03
GO:0030904 retromer complex	15	1.12e-01	-2.37e-01	2.89e-01
GO:0030027 lamellipodium	91	9.60e-05	2.37e-01	2.01e-03
GO:0051721 protein phosphatase 2A binding	14	1.25e-01	2.37e-01	3.09e-01
GO:0090128 regulation of synapse maturation	10	1.96e-01	2.36e-01	4.05e-01
GO:0030500 regulation of bone mineralization	12	1.57e-01	-2.36e-01	3.56e-01
GO:0010634 positive regulation of epithelial cell migration	19	7.48e-02	2.36e-01	2.28e-01
GO:0034704 calcium channel complex	10	1.96e-01	-2.36e-01	4.05e-01
GO:0008360 regulation of cell shape	60	1.59e-03	2.36e-01	1.64e-02
GO:0030159 signaling receptor complex adaptor activity	13	1.42e-01	2.35e-01	3.37e-01
GO:0061462 protein localization to lysosome	10	2.00e-01	-2.34e-01	4.09e-01
GO:0006805 xenobiotic metabolic process	17	9.54e-02	-2.34e-01	2.64e-01
GO:0045216 cell-cell junction organization	13	1.45e-01	2.33e-01	3.42e-01
GO:0007094 mitotic spindle assembly checkpoint signaling	19	7.88e-02	2.33e-01	2.35e-01
GO:0035115 embryonic forelimb morphogenesis	16	1.07e-01	2.33e-01	2.83e-01
GO:0005876 spindle microtubule	20	7.32e-02	2.31e-01	2.24e-01
GO:0046875 ephrin receptor binding	17	9.92e-02	2.31e-01	2.69e-01
GO:0045746 negative regulation of Notch signaling pathway	15	1.22e-01	2.31e-01	3.03e-01
GO:0034063 stress granule assembly	21	6.73e-02	2.31e-01	2.12e-01
GO:0001223 transcription coactivator binding	22	6.22e-02	2.30e-01	2.01e-01
GO:0043122 regulation of canonical NF-kappaB signal transduction	18	9.17e-02	2.30e-01	2.58e-01
GO:0005179 hormone activity	12	1.69e-01	-2.29e-01	3.72e-01
GO:0070412 R-SMAD binding	13	1.52e-01	2.29e-01	3.50e-01
GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site	16	1.13e-01	-2.29e-01	2.89e-01
GO:0043240 Fanconi anaemia nuclear complex	11	1.88e-01	-2.29e-01	3.98e-01
GO:0001707 mesoderm formation	15	1.25e-01	-2.29e-01	3.08e-01
GO:0003730 mRNA 3’-UTR binding	51	4.70e-03	2.29e-01	3.32e-02
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading	24	5.25e-02	2.29e-01	1.79e-01
GO:0034220 monoatomic ion transmembrane transport	20	7.73e-02	-2.28e-01	2.32e-01
GO:0071333 cellular response to glucose stimulus	12	1.72e-01	2.28e-01	3.76e-01
GO:0005923 bicellular tight junction	50	5.39e-03	2.28e-01	3.64e-02
GO:0003688 DNA replication origin binding	12	1.72e-01	2.27e-01	3.77e-01
GO:0031966 mitochondrial membrane	38	1.56e-02	-2.27e-01	7.63e-02
GO:0000166 nucleotide binding	36	1.86e-02	-2.27e-01	8.54e-02
GO:0009306 protein secretion	20	7.96e-02	-2.26e-01	2.35e-01
GO:0005581 collagen trimer	18	9.73e-02	-2.26e-01	2.67e-01
GO:0007129 homologous chromosome pairing at meiosis	14	1.44e-01	2.26e-01	3.40e-01
GO:0005765 lysosomal membrane	137	5.90e-06	-2.24e-01	2.28e-04
GO:0007369 gastrulation	10	2.19e-01	-2.24e-01	4.31e-01
GO:0043542 endothelial cell migration	13	1.62e-01	2.24e-01	3.63e-01
GO:1990782 protein tyrosine kinase binding	14	1.47e-01	2.24e-01	3.44e-01
GO:0032570 response to progesterone	13	1.63e-01	2.24e-01	3.64e-01
GO:0035267 NuA4 histone acetyltransferase complex	18	1.01e-01	2.23e-01	2.73e-01
GO:0050852 T cell receptor signaling pathway	50	6.40e-03	2.23e-01	4.12e-02
GO:0003785 actin monomer binding	13	1.64e-01	-2.23e-01	3.65e-01
GO:0016973 poly(A)+ mRNA export from nucleus	13	1.65e-01	2.22e-01	3.66e-01
GO:0042130 negative regulation of T cell proliferation	12	1.83e-01	2.22e-01	3.92e-01
GO:0009791 post-embryonic development	36	2.12e-02	2.22e-01	9.34e-02
GO:0042572 retinol metabolic process	12	1.84e-01	-2.22e-01	3.92e-01
GO:0006506 GPI anchor biosynthetic process	25	5.54e-02	-2.21e-01	1.84e-01
GO:0005819 spindle	54	4.98e-03	2.21e-01	3.43e-02
GO:0031032 actomyosin structure organization	17	1.15e-01	2.21e-01	2.91e-01
GO:0061077 chaperone-mediated protein folding	17	1.15e-01	-2.21e-01	2.92e-01
GO:0017116 single-stranded DNA helicase activity	16	1.27e-01	2.20e-01	3.10e-01
GO:0038084 vascular endothelial growth factor signaling pathway	23	6.82e-02	2.20e-01	2.13e-01
GO:0008305 integrin complex	17	1.17e-01	-2.20e-01	2.96e-01
GO:0000723 telomere maintenance	29	4.12e-02	2.19e-01	1.51e-01
GO:0032008 positive regulation of TOR signaling	11	2.09e-01	-2.19e-01	4.20e-01
GO:0006886 intracellular protein transport	158	2.14e-06	-2.19e-01	9.92e-05
GO:0051382 kinetochore assembly	11	2.10e-01	2.18e-01	4.22e-01
GO:0018279 protein N-linked glycosylation via asparagine	11	2.11e-01	-2.18e-01	4.22e-01
GO:0043010 camera-type eye development	22	7.70e-02	2.18e-01	2.32e-01
GO:0008380 RNA splicing	48	9.07e-03	2.18e-01	5.23e-02
GO:0035924 cellular response to vascular endothelial growth factor stimulus	16	1.32e-01	2.17e-01	3.18e-01
GO:2000377 regulation of reactive oxygen species metabolic process	10	2.34e-01	-2.17e-01	4.46e-01
GO:0031681 G-protein beta-subunit binding	10	2.35e-01	-2.17e-01	4.46e-01
GO:0016887 ATP hydrolysis activity	213	5.51e-08	2.17e-01	3.59e-06
GO:0048306 calcium-dependent protein binding	20	9.39e-02	-2.16e-01	2.61e-01
GO:0048821 erythrocyte development	15	1.47e-01	2.16e-01	3.44e-01
GO:0050918 positive chemotaxis	13	1.77e-01	2.16e-01	3.83e-01
GO:0045944 positive regulation of transcription by RNA polymerase II	525	3.69e-17	2.16e-01	7.20e-15
GO:0046718 symbiont entry into host cell	22	7.99e-02	2.16e-01	2.35e-01
GO:0032211 negative regulation of telomere maintenance via telomerase	10	2.38e-01	2.15e-01	4.49e-01
GO:0006376 mRNA splice site recognition	12	1.99e-01	2.14e-01	4.09e-01
GO:0000149 SNARE binding	31	3.89e-02	-2.14e-01	1.45e-01
GO:0045335 phagocytic vesicle	36	2.63e-02	-2.14e-01	1.09e-01
GO:0031334 positive regulation of protein-containing complex assembly	17	1.27e-01	-2.14e-01	3.10e-01
GO:0050679 positive regulation of epithelial cell proliferation	20	9.80e-02	2.14e-01	2.68e-01
GO:0051726 regulation of cell cycle	104	1.69e-04	2.14e-01	3.02e-03
GO:0010569 regulation of double-strand break repair via homologous recombination	10	2.42e-01	2.14e-01	4.53e-01
GO:0031122 cytoplasmic microtubule organization	28	5.05e-02	2.14e-01	1.75e-01
GO:0003743 translation initiation factor activity	39	2.12e-02	-2.13e-01	9.34e-02
GO:0006275 regulation of DNA replication	24	7.05e-02	2.13e-01	2.19e-01
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway	11	2.22e-01	-2.13e-01	4.34e-01
GO:0009952 anterior/posterior pattern specification	41	1.87e-02	2.12e-01	8.54e-02
GO:0005778 peroxisomal membrane	28	5.19e-02	-2.12e-01	1.78e-01
GO:0043124 negative regulation of canonical NF-kappaB signal transduction	36	2.77e-02	2.12e-01	1.13e-01
GO:0009653 anatomical structure morphogenesis	22	8.54e-02	2.12e-01	2.44e-01
GO:0008013 beta-catenin binding	46	1.29e-02	2.12e-01	6.67e-02
GO:0006672 ceramide metabolic process	10	2.47e-01	-2.12e-01	4.58e-01
GO:0030833 regulation of actin filament polymerization	21	9.34e-02	2.12e-01	2.60e-01
GO:0030670 phagocytic vesicle membrane	19	1.11e-01	-2.11e-01	2.89e-01
GO:0071320 cellular response to cAMP	19	1.12e-01	2.11e-01	2.89e-01
GO:0060382 regulation of DNA strand elongation	10	2.49e-01	2.10e-01	4.60e-01
GO:0006887 exocytosis	42	1.87e-02	-2.10e-01	8.54e-02
GO:0016604 nuclear body	175	1.77e-06	2.10e-01	8.41e-05
GO:0051489 regulation of filopodium assembly	10	2.51e-01	-2.10e-01	4.61e-01
GO:0030100 regulation of endocytosis	12	2.09e-01	-2.09e-01	4.20e-01
GO:0005665 RNA polymerase II, core complex	10	2.52e-01	-2.09e-01	4.61e-01
GO:0007596 blood coagulation	25	7.04e-02	-2.09e-01	2.19e-01
GO:0090575 RNA polymerase II transcription regulator complex	53	8.52e-03	2.09e-01	5.03e-02
GO:0004519 endonuclease activity	14	1.76e-01	2.09e-01	3.82e-01
GO:0001678 intracellular glucose homeostasis	17	1.36e-01	2.09e-01	3.25e-01
GO:0061157 mRNA destabilization	12	2.13e-01	2.08e-01	4.24e-01
GO:0030141 secretory granule	18	1.28e-01	-2.07e-01	3.10e-01
GO:0071339 MLL1 complex	18	1.28e-01	2.07e-01	3.10e-01
GO:0030334 regulation of cell migration	35	3.38e-02	2.07e-01	1.31e-01
GO:0016236 macroautophagy	16	1.51e-01	-2.07e-01	3.49e-01
GO:0003925 G protein activity	18	1.28e-01	-2.07e-01	3.10e-01
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	16	1.52e-01	-2.07e-01	3.50e-01
GO:0051787 misfolded protein binding	12	2.15e-01	-2.07e-01	4.27e-01
GO:0060976 coronary vasculature development	17	1.40e-01	2.07e-01	3.33e-01
GO:0106310 protein serine kinase activity	38	2.77e-02	2.06e-01	1.13e-01
GO:0090102 cochlea development	12	2.16e-01	2.06e-01	4.28e-01
GO:0000165 MAPK cascade	46	1.57e-02	2.06e-01	7.65e-02
GO:0006402 mRNA catabolic process	14	1.83e-01	2.06e-01	3.92e-01
GO:0030968 endoplasmic reticulum unfolded protein response	30	5.17e-02	-2.05e-01	1.78e-01
GO:0030032 lamellipodium assembly	20	1.12e-01	2.05e-01	2.89e-01
GO:0065003 protein-containing complex assembly	38	2.88e-02	2.05e-01	1.16e-01
GO:0048872 homeostasis of number of cells	14	1.84e-01	2.05e-01	3.92e-01
GO:0042026 protein refolding	12	2.19e-01	2.05e-01	4.31e-01
GO:0060070 canonical Wnt signaling pathway	57	7.59e-03	2.05e-01	4.70e-02
GO:0032874 positive regulation of stress-activated MAPK cascade	11	2.41e-01	2.04e-01	4.52e-01
GO:0005158 insulin receptor binding	13	2.04e-01	2.04e-01	4.15e-01
GO:0051287 NAD binding	18	1.37e-01	-2.03e-01	3.26e-01
GO:0031333 negative regulation of protein-containing complex assembly	16	1.60e-01	2.03e-01	3.63e-01
GO:0070402 NADPH binding	10	2.68e-01	-2.02e-01	4.82e-01
GO:0030946 protein tyrosine phosphatase activity, metal-dependent	15	1.75e-01	2.02e-01	3.80e-01
GO:0140793 histone H2AXY142 phosphatase activity	15	1.75e-01	2.02e-01	3.80e-01
GO:0005868 cytoplasmic dynein complex	14	1.90e-01	-2.02e-01	4.00e-01
GO:0043408 regulation of MAPK cascade	21	1.09e-01	2.02e-01	2.86e-01
GO:0016579 protein deubiquitination	28	6.49e-02	2.02e-01	2.06e-01
GO:0003899 DNA-directed 5’-3’ RNA polymerase activity	10	2.70e-01	2.02e-01	4.84e-01
GO:0009060 aerobic respiration	10	2.70e-01	-2.01e-01	4.84e-01
GO:0000423 mitophagy	31	5.25e-02	-2.01e-01	1.79e-01
GO:0001818 negative regulation of cytokine production	11	2.49e-01	-2.01e-01	4.60e-01
GO:0046856 phosphatidylinositol dephosphorylation	26	7.67e-02	-2.01e-01	2.31e-01
GO:0071347 cellular response to interleukin-1	17	1.52e-01	2.01e-01	3.50e-01
GO:0006606 protein import into nucleus	62	6.39e-03	2.00e-01	4.12e-02
GO:0043495 protein-membrane adaptor activity	17	1.53e-01	-2.00e-01	3.51e-01
GO:0006357 regulation of transcription by RNA polymerase II	549	2.50e-15	1.99e-01	3.99e-13
GO:0060348 bone development	26	7.97e-02	-1.99e-01	2.35e-01
GO:0017147 Wnt-protein binding	17	1.57e-01	1.98e-01	3.56e-01
GO:0071577 zinc ion transmembrane transport	10	2.78e-01	-1.98e-01	4.93e-01
GO:0070507 regulation of microtubule cytoskeleton organization	14	1.99e-01	1.98e-01	4.09e-01
GO:0120020 cholesterol transfer activity	12	2.35e-01	-1.98e-01	4.46e-01
GO:0030488 tRNA methylation	20	1.25e-01	-1.98e-01	3.09e-01
GO:0048511 rhythmic process	25	8.71e-02	1.98e-01	2.47e-01
GO:0038202 TORC1 signaling	12	2.36e-01	1.98e-01	4.47e-01
GO:0004842 ubiquitin-protein transferase activity	65	5.92e-03	1.98e-01	3.90e-02
GO:0006325 chromatin organization	66	5.58e-03	1.97e-01	3.73e-02
GO:0010507 negative regulation of autophagy	23	1.02e-01	1.97e-01	2.74e-01
GO:0070131 positive regulation of mitochondrial translation	10	2.81e-01	-1.97e-01	4.95e-01
GO:0030017 sarcomere	13	2.19e-01	-1.97e-01	4.31e-01
GO:0008017 microtubule binding	152	2.94e-05	1.97e-01	7.71e-04
GO:0032729 positive regulation of type II interferon production	23	1.03e-01	1.96e-01	2.75e-01
GO:0098685 Schaffer collateral - CA1 synapse	45	2.36e-02	1.95e-01	1.00e-01
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	17	1.64e-01	1.95e-01	3.65e-01
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific	182	5.95e-06	1.95e-01	2.28e-04
GO:0030890 positive regulation of B cell proliferation	21	1.22e-01	1.95e-01	3.03e-01
GO:0005783 endoplasmic reticulum	433	4.65e-12	-1.95e-01	5.11e-10
GO:0046329 negative regulation of JNK cascade	12	2.44e-01	1.94e-01	4.54e-01
GO:0010811 positive regulation of cell-substrate adhesion	13	2.25e-01	-1.94e-01	4.39e-01
GO:0008203 cholesterol metabolic process	30	6.61e-02	1.94e-01	2.09e-01
GO:0006898 receptor-mediated endocytosis	24	1.00e-01	1.94e-01	2.72e-01
GO:0098839 postsynaptic density membrane	34	5.07e-02	1.94e-01	1.76e-01
GO:0016342 catenin complex	13	2.27e-01	1.94e-01	4.39e-01
GO:0044291 cell-cell contact zone	14	2.11e-01	1.93e-01	4.22e-01
GO:0051539 4 iron, 4 sulfur cluster binding	33	5.51e-02	-1.93e-01	1.84e-01
GO:0007267 cell-cell signaling	13	2.28e-01	1.93e-01	4.39e-01
GO:0017018 myosin phosphatase activity	13	2.28e-01	-1.93e-01	4.39e-01
GO:0140791 histone H2AXS140 phosphatase activity	13	2.28e-01	-1.93e-01	4.39e-01
GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	13	2.28e-01	-1.93e-01	4.39e-01
GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	13	2.28e-01	-1.93e-01	4.39e-01
GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	13	2.28e-01	-1.93e-01	4.39e-01
GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	13	2.28e-01	-1.93e-01	4.39e-01
GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	13	2.28e-01	-1.93e-01	4.39e-01
GO:1990439 MAP kinase serine/threonine phosphatase activity	13	2.28e-01	-1.93e-01	4.39e-01
GO:0005881 cytoplasmic microtubule	30	6.77e-02	1.93e-01	2.12e-01
GO:0015030 Cajal body	26	8.90e-02	1.93e-01	2.51e-01
GO:0042995 cell projection	53	1.53e-02	1.93e-01	7.53e-02
GO:0071466 cellular response to xenobiotic stimulus	25	9.55e-02	1.93e-01	2.64e-01
GO:0005200 structural constituent of cytoskeleton	27	8.36e-02	1.92e-01	2.41e-01
GO:0080008 Cul4-RING E3 ubiquitin ligase complex	13	2.30e-01	1.92e-01	4.41e-01
GO:0016605 PML body	61	9.50e-03	1.92e-01	5.35e-02
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding	83	2.53e-03	1.92e-01	2.19e-02
GO:0035098 ESC/E(Z) complex	12	2.50e-01	1.92e-01	4.60e-01
GO:0035035 histone acetyltransferase binding	12	2.50e-01	1.92e-01	4.60e-01
GO:0033627 cell adhesion mediated by integrin	22	1.20e-01	-1.91e-01	3.00e-01
GO:0042149 cellular response to glucose starvation	28	8.02e-02	1.91e-01	2.35e-01
GO:0032012 regulation of ARF protein signal transduction	14	2.16e-01	1.91e-01	4.28e-01
GO:0005112 Notch binding	13	2.34e-01	1.91e-01	4.46e-01
GO:0010761 fibroblast migration	10	2.97e-01	1.90e-01	5.09e-01
GO:0043197 dendritic spine	45	2.73e-02	1.90e-01	1.13e-01
GO:0001725 stress fiber	42	3.31e-02	1.90e-01	1.29e-01
GO:0007131 reciprocal meiotic recombination	13	2.35e-01	1.90e-01	4.47e-01
GO:0045787 positive regulation of cell cycle	13	2.36e-01	1.90e-01	4.47e-01
GO:0040029 epigenetic regulation of gene expression	18	1.63e-01	1.90e-01	3.65e-01
GO:0016787 hydrolase activity	108	6.80e-04	1.89e-01	8.48e-03
GO:0005694 chromosome	76	4.34e-03	1.89e-01	3.15e-02
GO:0045893 positive regulation of DNA-templated transcription	223	1.28e-06	1.89e-01	6.25e-05
GO:0042742 defense response to bacterium	28	8.41e-02	1.89e-01	2.42e-01
GO:0000139 Golgi membrane	260	1.82e-07	-1.88e-01	1.07e-05
GO:0090734 site of DNA damage	22	1.26e-01	1.88e-01	3.10e-01
GO:0008047 enzyme activator activity	15	2.07e-01	1.88e-01	4.19e-01
GO:1901981 phosphatidylinositol phosphate binding	16	1.93e-01	-1.88e-01	4.03e-01
GO:0007163 establishment or maintenance of cell polarity	13	2.40e-01	-1.88e-01	4.52e-01
GO:0048167 regulation of synaptic plasticity	15	2.07e-01	1.88e-01	4.19e-01
GO:0012505 endomembrane system	97	1.41e-03	-1.88e-01	1.48e-02
GO:0055013 cardiac muscle cell development	11	2.81e-01	1.88e-01	4.95e-01
GO:0051403 stress-activated MAPK cascade	12	2.61e-01	1.87e-01	4.72e-01
GO:0006413 translational initiation	30	7.64e-02	-1.87e-01	2.31e-01
GO:0034446 substrate adhesion-dependent cell spreading	33	6.38e-02	1.87e-01	2.03e-01
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway	19	1.59e-01	1.87e-01	3.61e-01
GO:0008053 mitochondrial fusion	17	1.84e-01	-1.86e-01	3.92e-01
GO:2000045 regulation of G1/S transition of mitotic cell cycle	19	1.61e-01	1.86e-01	3.63e-01
GO:0031267 small GTPase binding	164	4.24e-05	1.86e-01	1.01e-03
GO:0061024 membrane organization	13	2.47e-01	-1.85e-01	4.58e-01
GO:0043565 sequence-specific DNA binding	56	1.65e-02	1.85e-01	7.96e-02
GO:0060021 roof of mouth development	36	5.45e-02	1.85e-01	1.83e-01
GO:0030175 filopodium	29	8.44e-02	1.85e-01	2.43e-01
GO:0030901 midbrain development	11	2.88e-01	1.85e-01	5.00e-01
GO:0007162 negative regulation of cell adhesion	16	2.00e-01	1.85e-01	4.10e-01
GO:0045892 negative regulation of DNA-templated transcription	173	2.88e-05	1.85e-01	7.67e-04
GO:0005096 GTPase activator activity	150	9.75e-05	1.85e-01	2.02e-03
GO:0010595 positive regulation of endothelial cell migration	26	1.04e-01	1.84e-01	2.76e-01
GO:0030054 cell junction	53	2.04e-02	1.84e-01	9.14e-02
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding	85	3.37e-03	1.84e-01	2.68e-02
GO:0060173 limb development	23	1.27e-01	1.84e-01	3.10e-01
GO:0005682 U5 snRNP	10	3.14e-01	1.84e-01	5.27e-01
GO:0007266 Rho protein signal transduction	33	6.77e-02	1.84e-01	2.12e-01
GO:0032420 stereocilium	14	2.34e-01	-1.84e-01	4.46e-01
GO:0005741 mitochondrial outer membrane	95	1.99e-03	-1.84e-01	1.91e-02
GO:0050885 neuromuscular process controlling balance	23	1.27e-01	1.84e-01	3.10e-01
GO:0031594 neuromuscular junction	34	6.40e-02	1.84e-01	2.04e-01
GO:0010212 response to ionizing radiation	24	1.20e-01	1.83e-01	3.00e-01
GO:0005201 extracellular matrix structural constituent	12	2.73e-01	1.83e-01	4.88e-01
GO:0007399 nervous system development	89	2.93e-03	1.83e-01	2.45e-02
GO:0060261 positive regulation of transcription initiation by RNA polymerase II	30	8.37e-02	1.83e-01	2.41e-01
GO:0030490 maturation of SSU-rRNA	12	2.74e-01	-1.82e-01	4.89e-01
GO:0008104 protein localization	69	8.92e-03	1.82e-01	5.19e-02
GO:1902018 negative regulation of cilium assembly	13	2.56e-01	1.82e-01	4.65e-01
GO:0006298 mismatch repair	16	2.08e-01	1.82e-01	4.19e-01
GO:0016601 Rac protein signal transduction	17	1.95e-01	1.82e-01	4.05e-01
GO:0051219 phosphoprotein binding	20	1.62e-01	1.81e-01	3.63e-01
GO:0042752 regulation of circadian rhythm	27	1.04e-01	1.81e-01	2.76e-01
GO:0001965 G-protein alpha-subunit binding	10	3.23e-01	-1.81e-01	5.35e-01
GO:0001843 neural tube closure	48	3.05e-02	1.81e-01	1.22e-01
GO:0001947 heart looping	23	1.34e-01	1.80e-01	3.22e-01
GO:0016922 nuclear receptor binding	21	1.53e-01	1.80e-01	3.50e-01
GO:0050840 extracellular matrix binding	16	2.12e-01	-1.80e-01	4.23e-01
GO:0031623 receptor internalization	21	1.53e-01	-1.80e-01	3.50e-01
GO:0032212 positive regulation of telomere maintenance via telomerase	17	1.99e-01	1.80e-01	4.09e-01
GO:0005516 calmodulin binding	66	1.15e-02	1.80e-01	6.08e-02
GO:0007030 Golgi organization	62	1.44e-02	-1.80e-01	7.24e-02
GO:0061351 neural precursor cell proliferation	14	2.45e-01	1.79e-01	4.56e-01
GO:0051131 chaperone-mediated protein complex assembly	14	2.49e-01	-1.78e-01	4.60e-01
GO:0006633 fatty acid biosynthetic process	21	1.59e-01	-1.78e-01	3.60e-01
GO:0097150 neuronal stem cell population maintenance	18	1.93e-01	1.77e-01	4.04e-01
GO:0007005 mitochondrion organization	62	1.60e-02	-1.77e-01	7.76e-02
GO:0050766 positive regulation of phagocytosis	14	2.52e-01	-1.77e-01	4.61e-01
GO:0007389 pattern specification process	14	2.52e-01	1.77e-01	4.61e-01
GO:0140297 DNA-binding transcription factor binding	70	1.08e-02	1.76e-01	5.79e-02
GO:0030016 myofibril	12	2.94e-01	-1.75e-01	5.04e-01
GO:0090314 positive regulation of protein targeting to membrane	12	2.94e-01	-1.75e-01	5.05e-01
GO:0015031 protein transport	173	7.73e-05	-1.75e-01	1.66e-03
GO:0010977 negative regulation of neuron projection development	17	2.13e-01	1.74e-01	4.25e-01
GO:0005109 frizzled binding	18	2.01e-01	1.74e-01	4.10e-01
GO:0005164 tumor necrosis factor receptor binding	13	2.78e-01	1.74e-01	4.93e-01
GO:0034332 adherens junction organization	12	2.97e-01	-1.74e-01	5.09e-01
GO:0004713 protein tyrosine kinase activity	34	8.03e-02	1.73e-01	2.35e-01
GO:0016328 lateral plasma membrane	24	1.42e-01	1.73e-01	3.36e-01
GO:0120009 intermembrane lipid transfer	16	2.31e-01	-1.73e-01	4.43e-01
GO:0004497 monooxygenase activity	11	3.23e-01	1.72e-01	5.35e-01
GO:0030552 cAMP binding	10	3.46e-01	-1.72e-01	5.56e-01
GO:0019904 protein domain specific binding	104	2.51e-03	1.72e-01	2.18e-02
GO:0016301 kinase activity	13	2.84e-01	-1.72e-01	4.99e-01
GO:0045070 positive regulation of viral genome replication	19	1.96e-01	1.71e-01	4.05e-01
GO:0005789 endoplasmic reticulum membrane	402	4.32e-09	-1.71e-01	3.04e-07
GO:0008286 insulin receptor signaling pathway	49	3.80e-02	1.71e-01	1.43e-01
GO:0060170 ciliary membrane	20	1.85e-01	-1.71e-01	3.94e-01
GO:0005085 guanyl-nucleotide exchange factor activity	143	4.34e-04	1.71e-01	6.05e-03
GO:0009887 animal organ morphogenesis	34	8.53e-02	1.71e-01	2.44e-01
GO:0035914 skeletal muscle cell differentiation	24	1.48e-01	1.71e-01	3.46e-01
GO:0008021 synaptic vesicle	47	4.35e-02	-1.70e-01	1.56e-01
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	11	3.29e-01	1.70e-01	5.42e-01
GO:0000049 tRNA binding	52	3.43e-02	-1.70e-01	1.33e-01
GO:0030316 osteoclast differentiation	28	1.21e-01	1.70e-01	3.01e-01
GO:0030425 dendrite	132	7.87e-04	1.69e-01	9.41e-03
GO:0035770 ribonucleoprotein granule	13	2.91e-01	1.69e-01	5.03e-01
GO:0005911 cell-cell junction	77	1.05e-02	1.69e-01	5.65e-02
GO:0043015 gamma-tubulin binding	21	1.82e-01	1.68e-01	3.90e-01
GO:0019894 kinesin binding	21	1.83e-01	1.68e-01	3.92e-01
GO:0042733 embryonic digit morphogenesis	30	1.12e-01	1.68e-01	2.89e-01
GO:0048513 animal organ development	11	3.36e-01	1.68e-01	5.48e-01
GO:0001662 behavioral fear response	12	3.15e-01	1.68e-01	5.27e-01
GO:0043484 regulation of RNA splicing	24	1.56e-01	1.67e-01	3.55e-01
GO:0097009 energy homeostasis	24	1.56e-01	1.67e-01	3.55e-01
GO:0001937 negative regulation of endothelial cell proliferation	12	3.16e-01	1.67e-01	5.29e-01
GO:0031941 filamentous actin	18	2.20e-01	1.67e-01	4.32e-01
GO:0070411 I-SMAD binding	11	3.38e-01	1.67e-01	5.48e-01
GO:0008333 endosome to lysosome transport	32	1.03e-01	-1.67e-01	2.74e-01
GO:0071539 protein localization to centrosome	20	1.97e-01	1.67e-01	4.06e-01
GO:0045879 negative regulation of smoothened signaling pathway	15	2.64e-01	1.66e-01	4.78e-01
GO:0140861 DNA repair-dependent chromatin remodeling	14	2.81e-01	1.66e-01	4.95e-01
GO:0019882 antigen processing and presentation	11	3.40e-01	-1.66e-01	5.52e-01
GO:0000278 mitotic cell cycle	53	3.67e-02	1.66e-01	1.39e-01
GO:0002376 immune system process	13	3.01e-01	-1.66e-01	5.13e-01
GO:0006397 mRNA processing	73	1.47e-02	1.65e-01	7.35e-02
GO:0032869 cellular response to insulin stimulus	33	1.01e-01	1.65e-01	2.72e-01
GO:0012506 vesicle membrane	16	2.53e-01	-1.65e-01	4.62e-01
GO:0016525 negative regulation of angiogenesis	35	9.25e-02	1.64e-01	2.59e-01
GO:0006612 protein targeting to membrane	24	1.64e-01	-1.64e-01	3.65e-01
GO:0019902 phosphatase binding	23	1.73e-01	1.64e-01	3.77e-01
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity	19	2.15e-01	1.64e-01	4.27e-01
GO:0036211 protein modification process	16	2.56e-01	-1.64e-01	4.65e-01
GO:2000352 negative regulation of endothelial cell apoptotic process	14	2.88e-01	1.64e-01	5.00e-01
GO:0043525 positive regulation of neuron apoptotic process	18	2.29e-01	1.64e-01	4.39e-01
GO:0051959 dynein light intermediate chain binding	15	2.76e-01	1.63e-01	4.90e-01
GO:0090307 mitotic spindle assembly	30	1.23e-01	1.63e-01	3.05e-01
GO:0034599 cellular response to oxidative stress	44	6.23e-02	-1.62e-01	2.01e-01
GO:0007160 cell-matrix adhesion	40	7.58e-02	-1.62e-01	2.30e-01
GO:0071233 cellular response to L-leucine	10	3.75e-01	1.62e-01	5.85e-01
GO:0001822 kidney development	51	4.63e-02	1.61e-01	1.63e-01
GO:0048705 skeletal system morphogenesis	15	2.80e-01	-1.61e-01	4.95e-01
GO:0001702 gastrulation with mouth forming second	10	3.79e-01	1.61e-01	5.89e-01
GO:0033077 T cell differentiation in thymus	18	2.38e-01	1.61e-01	4.49e-01
GO:0080025 phosphatidylinositol-3,5-bisphosphate binding	15	2.81e-01	-1.61e-01	4.95e-01
GO:0007409 axonogenesis	40	7.98e-02	1.60e-01	2.35e-01
GO:0006986 response to unfolded protein	12	3.37e-01	-1.60e-01	5.48e-01
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment	35	1.01e-01	-1.60e-01	2.73e-01
GO:0007155 cell adhesion	103	5.07e-03	1.60e-01	3.47e-02
GO:0000124 SAGA complex	15	2.85e-01	1.60e-01	4.99e-01
GO:0005879 axonemal microtubule	10	3.83e-01	1.59e-01	5.92e-01
GO:0007268 chemical synaptic transmission	33	1.13e-01	1.59e-01	2.90e-01
GO:0000146 microfilament motor activity	18	2.42e-01	1.59e-01	4.53e-01
GO:0008266 poly(U) RNA binding	16	2.70e-01	1.59e-01	4.84e-01
GO:0090263 positive regulation of canonical Wnt signaling pathway	61	3.25e-02	1.58e-01	1.28e-01
GO:0006281 DNA repair	95	7.88e-03	1.58e-01	4.80e-02
GO:0046034 ATP metabolic process	13	3.25e-01	-1.58e-01	5.38e-01
GO:0031463 Cul3-RING ubiquitin ligase complex	41	8.07e-02	-1.58e-01	2.36e-01
GO:0003727 single-stranded RNA binding	21	2.11e-01	1.58e-01	4.22e-01
GO:0007411 axon guidance	75	1.84e-02	1.58e-01	8.54e-02
GO:0006366 transcription by RNA polymerase II	73	2.02e-02	1.57e-01	9.10e-02
GO:0070979 protein K11-linked ubiquitination	22	2.02e-01	-1.57e-01	4.11e-01
GO:0005874 microtubule	129	2.08e-03	1.57e-01	1.95e-02
GO:0005759 mitochondrial matrix	119	3.17e-03	-1.57e-01	2.59e-02
GO:0048536 spleen development	23	1.96e-01	1.56e-01	4.05e-01
GO:0008542 visual learning	20	2.28e-01	1.56e-01	4.39e-01
GO:0090398 cellular senescence	19	2.43e-01	1.55e-01	4.54e-01
GO:0005021 vascular endothelial growth factor receptor activity	15	3.00e-01	1.55e-01	5.12e-01
GO:0051123 RNA polymerase II preinitiation complex assembly	16	2.85e-01	-1.54e-01	4.99e-01
GO:0003779 actin binding	138	1.80e-03	1.54e-01	1.78e-02
GO:0004843 cysteine-type deubiquitinase activity	57	4.43e-02	1.54e-01	1.58e-01
GO:0048706 embryonic skeletal system development	16	2.86e-01	1.54e-01	5.00e-01
GO:0005245 voltage-gated calcium channel activity	12	3.56e-01	1.54e-01	5.66e-01
GO:0000086 G2/M transition of mitotic cell cycle	25	1.84e-01	1.54e-01	3.92e-01
GO:0035264 multicellular organism growth	66	3.16e-02	1.53e-01	1.25e-01
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation	14	3.22e-01	1.53e-01	5.35e-01
GO:0045332 phospholipid translocation	15	3.05e-01	-1.53e-01	5.18e-01
GO:0005902 microvillus	28	1.62e-01	-1.53e-01	3.63e-01
GO:0017148 negative regulation of translation	43	8.37e-02	1.53e-01	2.41e-01
GO:0004896 cytokine receptor activity	20	2.40e-01	1.52e-01	4.52e-01
GO:0004860 protein kinase inhibitor activity	19	2.52e-01	-1.52e-01	4.61e-01
GO:0032007 negative regulation of TOR signaling	18	2.65e-01	-1.52e-01	4.78e-01
GO:0090443 FAR/SIN/STRIPAK complex	12	3.63e-01	-1.52e-01	5.74e-01
GO:0035904 aorta development	15	3.10e-01	1.51e-01	5.25e-01
GO:0004674 protein serine/threonine kinase activity	202	2.20e-04	1.51e-01	3.76e-03
GO:0005262 calcium channel activity	22	2.20e-01	-1.51e-01	4.31e-01
GO:0005739 mitochondrion	607	2.73e-10	-1.51e-01	2.28e-08
GO:0032580 Golgi cisterna membrane	26	1.83e-01	-1.51e-01	3.92e-01
GO:0086091 regulation of heart rate by cardiac conduction	17	2.82e-01	1.51e-01	4.96e-01
GO:0033344 cholesterol efflux	11	3.89e-01	-1.50e-01	5.99e-01
GO:0042056 chemoattractant activity	11	3.90e-01	1.50e-01	6.01e-01
GO:0008283 cell population proliferation	65	3.71e-02	1.50e-01	1.40e-01
GO:0070006 metalloaminopeptidase activity	15	3.16e-01	-1.49e-01	5.29e-01
GO:0050680 negative regulation of epithelial cell proliferation	24	2.06e-01	1.49e-01	4.18e-01
GO:0043021 ribonucleoprotein complex binding	23	2.16e-01	1.49e-01	4.28e-01
GO:0009966 regulation of signal transduction	37	1.17e-01	1.49e-01	2.96e-01
GO:0030155 regulation of cell adhesion	18	2.75e-01	1.49e-01	4.90e-01
GO:1990837 sequence-specific double-stranded DNA binding	47	7.80e-02	1.49e-01	2.34e-01
GO:0007611 learning or memory	15	3.19e-01	-1.49e-01	5.32e-01
GO:0060324 face development	14	3.37e-01	1.48e-01	5.48e-01
GO:0004177 aminopeptidase activity	13	3.55e-01	-1.48e-01	5.65e-01
GO:1990498 mitotic spindle microtubule	10	4.17e-01	1.48e-01	6.26e-01
GO:0070301 cellular response to hydrogen peroxide	23	2.19e-01	-1.48e-01	4.31e-01
GO:0030206 chondroitin sulfate biosynthetic process	11	3.97e-01	1.48e-01	6.09e-01
GO:0001525 angiogenesis	86	1.84e-02	1.47e-01	8.54e-02
GO:0001784 phosphotyrosine residue binding	27	1.87e-01	1.47e-01	3.96e-01
GO:0016529 sarcoplasmic reticulum	13	3.60e-01	1.47e-01	5.71e-01
GO:0030878 thyroid gland development	14	3.42e-01	1.47e-01	5.53e-01
GO:0005385 zinc ion transmembrane transporter activity	15	3.26e-01	-1.47e-01	5.38e-01
GO:0051117 ATPase binding	44	9.33e-02	-1.46e-01	2.60e-01
GO:0048488 synaptic vesicle endocytosis	20	2.58e-01	1.46e-01	4.67e-01
GO:0070372 regulation of ERK1 and ERK2 cascade	12	3.81e-01	1.46e-01	5.92e-01
GO:0030183 B cell differentiation	27	1.89e-01	1.46e-01	4.00e-01
GO:0030140 trans-Golgi network transport vesicle	11	4.02e-01	-1.46e-01	6.16e-01
GO:0001968 fibronectin binding	10	4.24e-01	1.46e-01	6.33e-01
GO:0050681 nuclear androgen receptor binding	16	3.13e-01	1.46e-01	5.26e-01
GO:0051216 cartilage development	20	2.59e-01	1.46e-01	4.70e-01
GO:0007507 heart development	78	2.63e-02	1.46e-01	1.09e-01
GO:0055085 transmembrane transport	82	2.29e-02	-1.45e-01	9.83e-02
GO:0060339 negative regulation of type I interferon-mediated signaling pathway	13	3.65e-01	1.45e-01	5.76e-01
GO:0001508 action potential	11	4.05e-01	1.45e-01	6.18e-01
GO:0022008 neurogenesis	31	1.63e-01	1.45e-01	3.64e-01
GO:0070936 protein K48-linked ubiquitination	68	3.94e-02	-1.45e-01	1.46e-01
GO:0042472 inner ear morphogenesis	27	1.96e-01	1.44e-01	4.05e-01
GO:0035987 endodermal cell differentiation	22	2.43e-01	1.44e-01	4.54e-01
GO:1904263 positive regulation of TORC1 signaling	35	1.42e-01	-1.44e-01	3.36e-01
GO:1904047 S-adenosyl-L-methionine binding	13	3.71e-01	-1.43e-01	5.82e-01
GO:0006644 phospholipid metabolic process	11	4.10e-01	-1.43e-01	6.21e-01
GO:0005669 transcription factor TFIID complex	22	2.46e-01	-1.43e-01	4.57e-01
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity	14	3.54e-01	1.43e-01	5.65e-01
GO:0015629 actin cytoskeleton	111	9.41e-03	1.43e-01	5.34e-02
GO:0015908 fatty acid transport	11	4.12e-01	1.43e-01	6.23e-01
GO:0001222 transcription corepressor binding	27	1.99e-01	1.43e-01	4.09e-01
GO:0030163 protein catabolic process	30	1.77e-01	1.43e-01	3.83e-01
GO:0043524 negative regulation of neuron apoptotic process	51	7.95e-02	1.42e-01	2.35e-01
GO:0050830 defense response to Gram-positive bacterium	15	3.41e-01	1.42e-01	5.52e-01
GO:0000724 double-strand break repair via homologous recombination	71	3.98e-02	1.41e-01	1.47e-01
GO:0000387 spliceosomal snRNP assembly	17	3.14e-01	-1.41e-01	5.27e-01
GO:0045211 postsynaptic membrane	57	6.61e-02	1.41e-01	2.09e-01
GO:0030659 cytoplasmic vesicle membrane	43	1.10e-01	1.41e-01	2.88e-01
GO:0003007 heart morphogenesis	15	3.46e-01	1.41e-01	5.55e-01
GO:0016251 RNA polymerase II general transcription initiation factor activity	22	2.56e-01	-1.40e-01	4.65e-01
GO:0032526 response to retinoic acid	15	3.48e-01	1.40e-01	5.58e-01
GO:0070371 ERK1 and ERK2 cascade	20	2.79e-01	1.40e-01	4.95e-01
GO:0000974 Prp19 complex	10	4.44e-01	1.40e-01	6.48e-01
GO:0071230 cellular response to amino acid stimulus	29	1.94e-01	-1.40e-01	4.04e-01
GO:0030672 synaptic vesicle membrane	43	1.14e-01	-1.39e-01	2.91e-01
GO:0031012 extracellular matrix	88	2.46e-02	1.39e-01	1.03e-01
GO:0006468 protein phosphorylation	12	4.06e-01	1.39e-01	6.18e-01
GO:0030165 PDZ domain binding	29	1.98e-01	1.38e-01	4.08e-01
GO:0032924 activin receptor signaling pathway	12	4.07e-01	1.38e-01	6.19e-01
GO:0051592 response to calcium ion	20	2.86e-01	-1.38e-01	5.00e-01
GO:0043113 receptor clustering	12	4.09e-01	-1.38e-01	6.20e-01
GO:0045453 bone resorption	11	4.31e-01	1.37e-01	6.37e-01
GO:0006261 DNA-templated DNA replication	18	3.14e-01	1.37e-01	5.27e-01
GO:0031965 nuclear membrane	121	9.33e-03	1.37e-01	5.33e-02
GO:0071711 basement membrane organization	11	4.33e-01	-1.37e-01	6.40e-01
GO:0006622 protein targeting to lysosome	15	3.61e-01	-1.36e-01	5.72e-01
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	13	3.95e-01	1.36e-01	6.07e-01
GO:0030036 actin cytoskeleton organization	107	1.51e-02	1.36e-01	7.49e-02
GO:0003756 protein disulfide isomerase activity	10	4.56e-01	-1.36e-01	6.55e-01
GO:0034707 chloride channel complex	10	4.56e-01	1.36e-01	6.55e-01
GO:0032722 positive regulation of chemokine production	11	4.35e-01	-1.36e-01	6.41e-01
GO:0019901 protein kinase binding	235	3.41e-04	1.36e-01	5.13e-03
GO:0043679 axon terminus	18	3.18e-01	1.36e-01	5.31e-01
GO:0016358 dendrite development	17	3.32e-01	1.36e-01	5.46e-01
GO:0004197 cysteine-type endopeptidase activity	37	1.55e-01	-1.35e-01	3.53e-01
GO:0005254 chloride channel activity	19	3.08e-01	1.35e-01	5.22e-01
GO:0060395 SMAD protein signal transduction	14	3.82e-01	1.35e-01	5.92e-01
GO:0003924 GTPase activity	175	2.11e-03	-1.35e-01	1.95e-02
GO:0014032 neural crest cell development	11	4.39e-01	-1.35e-01	6.45e-01
GO:0006869 lipid transport	26	2.35e-01	-1.35e-01	4.46e-01
GO:0007264 small GTPase-mediated signal transduction	47	1.11e-01	1.35e-01	2.88e-01
GO:0001650 fibrillar center	102	1.92e-02	1.34e-01	8.74e-02
GO:0016485 protein processing	40	1.42e-01	-1.34e-01	3.37e-01
GO:0008168 methyltransferase activity	13	4.03e-01	-1.34e-01	6.16e-01
GO:0090090 negative regulation of canonical Wnt signaling pathway	70	5.33e-02	1.34e-01	1.80e-01
GO:0140311 protein sequestering activity	18	3.26e-01	1.34e-01	5.38e-01
GO:0010906 regulation of glucose metabolic process	10	4.67e-01	-1.33e-01	6.64e-01
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle	27	2.32e-01	1.33e-01	4.44e-01
GO:0000132 establishment of mitotic spindle orientation	26	2.43e-01	1.32e-01	4.54e-01
GO:0046983 protein dimerization activity	69	5.75e-02	1.32e-01	1.89e-01
GO:0030220 platelet formation	11	4.48e-01	1.32e-01	6.51e-01
GO:0032735 positive regulation of interleukin-12 production	12	4.29e-01	1.32e-01	6.36e-01
GO:0006302 double-strand break repair	45	1.26e-01	1.32e-01	3.10e-01
GO:0015813 L-glutamate transmembrane transport	11	4.49e-01	1.32e-01	6.51e-01
GO:0030336 negative regulation of cell migration	50	1.07e-01	1.32e-01	2.83e-01
GO:0001558 regulation of cell growth	24	2.65e-01	1.31e-01	4.79e-01
GO:0001541 ovarian follicle development	19	3.22e-01	1.31e-01	5.35e-01
GO:0005686 U2 snRNP	16	3.65e-01	1.31e-01	5.76e-01
GO:0008180 COP9 signalosome	21	3.00e-01	1.31e-01	5.12e-01
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage	24	2.67e-01	1.31e-01	4.82e-01
GO:0098794 postsynapse	66	6.66e-02	1.31e-01	2.10e-01
GO:0033209 tumor necrosis factor-mediated signaling pathway	15	3.82e-01	-1.30e-01	5.92e-01
GO:0005811 lipid droplet	42	1.45e-01	-1.30e-01	3.42e-01
GO:0030154 cell differentiation	141	7.83e-03	1.30e-01	4.79e-02
GO:0045880 positive regulation of smoothened signaling pathway	22	2.92e-01	1.30e-01	5.04e-01
GO:0006654 phosphatidic acid biosynthetic process	11	4.56e-01	-1.30e-01	6.55e-01
GO:0072657 protein localization to membrane	18	3.41e-01	1.30e-01	5.52e-01
GO:0008045 motor neuron axon guidance	12	4.38e-01	1.29e-01	6.44e-01
GO:0035567 non-canonical Wnt signaling pathway	13	4.20e-01	1.29e-01	6.30e-01
GO:0010842 retina layer formation	11	4.59e-01	1.29e-01	6.56e-01
GO:0048863 stem cell differentiation	21	3.07e-01	1.29e-01	5.21e-01
GO:0046854 phosphatidylinositol phosphate biosynthetic process	18	3.44e-01	1.29e-01	5.54e-01
GO:0099170 postsynaptic modulation of chemical synaptic transmission	13	4.22e-01	1.29e-01	6.30e-01
GO:0051016 barbed-end actin filament capping	15	3.89e-01	-1.28e-01	6.00e-01
GO:0070830 bicellular tight junction assembly	19	3.33e-01	1.28e-01	5.46e-01
GO:0004198 calcium-dependent cysteine-type endopeptidase activity	10	4.83e-01	1.28e-01	6.81e-01
GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction	35	1.90e-01	1.28e-01	4.00e-01
GO:0001658 branching involved in ureteric bud morphogenesis	16	3.76e-01	1.28e-01	5.86e-01
GO:0006270 DNA replication initiation	19	3.35e-01	1.28e-01	5.48e-01
GO:0005905 clathrin-coated pit	30	2.26e-01	1.28e-01	4.39e-01
GO:0005929 cilium	77	5.29e-02	-1.28e-01	1.80e-01
GO:0005524 ATP binding	888	1.84e-10	1.27e-01	1.62e-08
GO:0005930 axoneme	48	1.28e-01	-1.27e-01	3.10e-01
GO:0005884 actin filament	43	1.49e-01	1.27e-01	3.48e-01
GO:0015026 coreceptor activity	13	4.28e-01	1.27e-01	6.36e-01
GO:0045724 positive regulation of cilium assembly	13	4.28e-01	1.27e-01	6.36e-01
GO:0042734 presynaptic membrane	36	1.88e-01	1.27e-01	3.97e-01
GO:0004725 protein tyrosine phosphatase activity	44	1.46e-01	1.27e-01	3.43e-01
GO:0003690 double-stranded DNA binding	35	1.95e-01	1.27e-01	4.05e-01
GO:0030515 snoRNA binding	14	4.13e-01	1.26e-01	6.23e-01
GO:0006446 regulation of translational initiation	17	3.67e-01	1.26e-01	5.79e-01
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway	41	1.62e-01	1.26e-01	3.63e-01
GO:0016282 eukaryotic 43S preinitiation complex	14	4.14e-01	-1.26e-01	6.24e-01
GO:0008198 ferrous iron binding	12	4.50e-01	-1.26e-01	6.51e-01
GO:0001516 prostaglandin biosynthetic process	10	4.91e-01	-1.26e-01	6.88e-01
GO:0031397 negative regulation of protein ubiquitination	33	2.11e-01	-1.26e-01	4.22e-01
GO:0006914 autophagy	44	1.49e-01	-1.26e-01	3.47e-01
GO:0005634 nucleus	2123	1.73e-20	1.26e-01	6.09e-18
GO:0140627 ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	10	4.92e-01	-1.26e-01	6.88e-01
GO:0031901 early endosome membrane	75	6.14e-02	-1.25e-01	1.99e-01
GO:0003723 RNA binding	372	3.83e-05	1.25e-01	9.35e-04
GO:0050804 modulation of chemical synaptic transmission	35	2.01e-01	1.25e-01	4.11e-01
GO:0034644 cellular response to UV	33	2.15e-01	1.25e-01	4.27e-01
GO:0008306 associative learning	10	4.95e-01	1.25e-01	6.92e-01
GO:0010628 positive regulation of gene expression	147	9.26e-03	1.25e-01	5.30e-02
GO:0035331 negative regulation of hippo signaling	18	3.62e-01	1.24e-01	5.72e-01
GO:0030544 Hsp70 protein binding	29	2.48e-01	-1.24e-01	4.59e-01
GO:0004721 phosphoprotein phosphatase activity	21	3.26e-01	-1.24e-01	5.38e-01
GO:0045171 intercellular bridge	55	1.12e-01	1.24e-01	2.89e-01
GO:0030282 bone mineralization	22	3.15e-01	-1.24e-01	5.27e-01
GO:0098609 cell-cell adhesion	80	5.59e-02	1.24e-01	1.85e-01
GO:0002931 response to ischemia	10	4.99e-01	-1.23e-01	6.96e-01
GO:0005154 epidermal growth factor receptor binding	19	3.52e-01	-1.23e-01	5.63e-01
GO:0002088 lens development in camera-type eye	13	4.42e-01	1.23e-01	6.46e-01
GO:0090201 negative regulation of release of cytochrome c from mitochondria	11	4.82e-01	-1.22e-01	6.81e-01
GO:2000773 negative regulation of cellular senescence	12	4.65e-01	-1.22e-01	6.62e-01
GO:0032868 response to insulin	22	3.23e-01	1.22e-01	5.35e-01
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle	23	3.12e-01	1.22e-01	5.26e-01
GO:0045931 positive regulation of mitotic cell cycle	14	4.31e-01	-1.22e-01	6.37e-01
GO:0048787 presynaptic active zone membrane	11	4.86e-01	-1.21e-01	6.84e-01
GO:0071805 potassium ion transmembrane transport	39	1.90e-01	-1.21e-01	4.00e-01
GO:0006367 transcription initiation at RNA polymerase II promoter	20	3.49e-01	-1.21e-01	5.58e-01
GO:0140801 histone H2AXY142 kinase activity	22	3.26e-01	1.21e-01	5.38e-01
GO:1904019 epithelial cell apoptotic process	13	4.51e-01	1.21e-01	6.51e-01
GO:0043235 receptor complex	79	6.42e-02	1.21e-01	2.04e-01
GO:0019005 SCF ubiquitin ligase complex	43	1.74e-01	-1.20e-01	3.80e-01
GO:0035249 synaptic transmission, glutamatergic	16	4.07e-01	1.20e-01	6.19e-01
GO:0007275 multicellular organism development	26	2.92e-01	1.19e-01	5.04e-01
GO:0005856 cytoskeleton	173	7.01e-03	1.19e-01	4.42e-02
GO:0016477 cell migration	135	1.72e-02	1.19e-01	8.17e-02
GO:0031514 motile cilium	35	2.24e-01	-1.19e-01	4.39e-01
GO:0051259 protein complex oligomerization	14	4.42e-01	-1.19e-01	6.46e-01
GO:0007064 mitotic sister chromatid cohesion	10	5.16e-01	1.19e-01	7.13e-01
GO:0035024 negative regulation of Rho protein signal transduction	14	4.43e-01	-1.18e-01	6.46e-01
GO:0098586 cellular response to virus	22	3.36e-01	1.18e-01	5.48e-01
GO:0015631 tubulin binding	27	2.88e-01	1.18e-01	5.00e-01
GO:0070050 neuron cellular homeostasis	15	4.29e-01	-1.18e-01	6.36e-01
GO:0042254 ribosome biogenesis	16	4.15e-01	1.18e-01	6.24e-01
GO:0060326 cell chemotaxis	29	2.74e-01	1.17e-01	4.89e-01
GO:0004535 poly(A)-specific ribonuclease activity	10	5.20e-01	-1.17e-01	7.17e-01
GO:0031072 heat shock protein binding	27	2.93e-01	1.17e-01	5.04e-01
GO:0051879 Hsp90 protein binding	27	2.93e-01	1.17e-01	5.04e-01
GO:0030127 COPII vesicle coat	10	5.24e-01	-1.16e-01	7.17e-01
GO:0098719 sodium ion import across plasma membrane	10	5.24e-01	1.16e-01	7.17e-01
GO:0030073 insulin secretion	13	4.68e-01	1.16e-01	6.66e-01
GO:0051894 positive regulation of focal adhesion assembly	15	4.38e-01	1.16e-01	6.44e-01
GO:0009925 basal plasma membrane	12	4.89e-01	-1.15e-01	6.86e-01
GO:0048741 skeletal muscle fiber development	16	4.26e-01	1.15e-01	6.34e-01
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle	15	4.41e-01	1.15e-01	6.46e-01
GO:0030424 axon	120	2.99e-02	1.15e-01	1.20e-01
GO:0045296 cadherin binding	28	2.93e-01	1.15e-01	5.04e-01
GO:0000077 DNA damage checkpoint signaling	26	3.12e-01	1.15e-01	5.26e-01
GO:1904646 cellular response to amyloid-beta	11	5.11e-01	-1.14e-01	7.08e-01
GO:0006611 protein export from nucleus	22	3.54e-01	1.14e-01	5.64e-01
GO:0007605 sensory perception of sound	53	1.51e-01	1.14e-01	3.49e-01
GO:0007059 chromosome segregation	41	2.07e-01	1.14e-01	4.19e-01
GO:0050919 negative chemotaxis	21	3.68e-01	-1.14e-01	5.79e-01
GO:0099560 synaptic membrane adhesion	14	4.63e-01	1.13e-01	6.60e-01
GO:0019905 syntaxin binding	25	3.27e-01	-1.13e-01	5.39e-01
GO:0045727 positive regulation of translation	36	2.40e-01	1.13e-01	4.52e-01
GO:0030971 receptor tyrosine kinase binding	32	2.69e-01	1.13e-01	4.84e-01
GO:0046716 muscle cell cellular homeostasis	15	4.51e-01	-1.12e-01	6.51e-01
GO:0000307 cyclin-dependent protein kinase holoenzyme complex	21	3.73e-01	-1.12e-01	5.85e-01
GO:0048384 retinoic acid receptor signaling pathway	11	5.20e-01	1.12e-01	7.17e-01
GO:0045814 negative regulation of gene expression, epigenetic	16	4.39e-01	1.12e-01	6.45e-01
GO:0048568 embryonic organ development	15	4.57e-01	1.11e-01	6.55e-01
GO:0097730 non-motile cilium	15	4.57e-01	-1.11e-01	6.55e-01
GO:0070847 core mediator complex	19	4.03e-01	-1.11e-01	6.16e-01
GO:0043588 skin development	23	3.58e-01	1.11e-01	5.68e-01
GO:0009566 fertilization	12	5.07e-01	1.11e-01	7.05e-01
GO:0035591 signaling adaptor activity	40	2.28e-01	1.10e-01	4.39e-01
GO:0033173 calcineurin-NFAT signaling cascade	10	5.46e-01	1.10e-01	7.36e-01
GO:0030521 androgen receptor signaling pathway	12	5.09e-01	1.10e-01	7.06e-01
GO:0004879 nuclear receptor activity	39	2.35e-01	1.10e-01	4.46e-01
GO:0097550 transcription preinitiation complex	12	5.11e-01	-1.10e-01	7.08e-01
GO:0001778 plasma membrane repair	16	4.50e-01	-1.09e-01	6.51e-01
GO:0005847 mRNA cleavage and polyadenylation specificity factor complex	11	5.31e-01	1.09e-01	7.22e-01
GO:0045672 positive regulation of osteoclast differentiation	11	5.31e-01	1.09e-01	7.22e-01
GO:0006417 regulation of translation	44	2.12e-01	1.09e-01	4.23e-01
GO:0035861 site of double-strand break	58	1.54e-01	1.08e-01	3.53e-01
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway	13	5.01e-01	1.08e-01	6.97e-01
GO:0045600 positive regulation of fat cell differentiation	21	3.94e-01	1.07e-01	6.06e-01
GO:0008270 zinc ion binding	398	2.61e-04	1.07e-01	4.25e-03
GO:0035401 histone H3Y41 kinase activity	21	3.95e-01	1.07e-01	6.07e-01
GO:0005788 endoplasmic reticulum lumen	40	2.41e-01	-1.07e-01	4.52e-01
GO:0005938 cell cortex	75	1.10e-01	1.07e-01	2.88e-01
GO:0045785 positive regulation of cell adhesion	15	4.75e-01	1.07e-01	6.73e-01
GO:0051496 positive regulation of stress fiber assembly	31	3.05e-01	1.07e-01	5.18e-01
GO:0045177 apical part of cell	34	2.83e-01	1.07e-01	4.96e-01
GO:0004888 transmembrane signaling receptor activity	23	3.77e-01	-1.06e-01	5.87e-01
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand	12	5.24e-01	1.06e-01	7.17e-01
GO:0030018 Z disc	49	2.00e-01	1.06e-01	4.09e-01
GO:0030218 erythrocyte differentiation	28	3.33e-01	1.06e-01	5.46e-01
GO:0019903 protein phosphatase binding	49	2.00e-01	1.06e-01	4.10e-01
GO:0003684 damaged DNA binding	34	2.86e-01	1.06e-01	5.00e-01
GO:0005802 trans-Golgi network	99	6.97e-02	-1.06e-01	2.17e-01
GO:0032456 endocytic recycling	42	2.37e-01	-1.06e-01	4.47e-01
GO:0030332 cyclin binding	20	4.15e-01	1.05e-01	6.24e-01
GO:0001501 skeletal system development	34	2.88e-01	1.05e-01	5.00e-01
GO:0036503 ERAD pathway	59	1.62e-01	-1.05e-01	3.63e-01
GO:0012507 ER to Golgi transport vesicle membrane	11	5.46e-01	1.05e-01	7.36e-01
GO:0008023 transcription elongation factor complex	14	4.97e-01	1.05e-01	6.94e-01
GO:0071456 cellular response to hypoxia	34	2.90e-01	1.05e-01	5.03e-01
GO:0030295 protein kinase activator activity	21	4.06e-01	1.05e-01	6.18e-01
GO:0006513 protein monoubiquitination	27	3.47e-01	-1.05e-01	5.56e-01
GO:0005525 GTP binding	211	9.05e-03	-1.05e-01	5.23e-02
GO:0030010 establishment of cell polarity	18	4.45e-01	1.04e-01	6.49e-01
GO:0051015 actin filament binding	116	5.46e-02	1.03e-01	1.83e-01
GO:0045766 positive regulation of angiogenesis	53	1.94e-01	1.03e-01	4.04e-01
GO:0055088 lipid homeostasis	18	4.51e-01	-1.03e-01	6.51e-01
GO:0005643 nuclear pore	33	3.07e-01	1.03e-01	5.21e-01
GO:0051260 protein homooligomerization	48	2.19e-01	1.03e-01	4.31e-01
GO:0050750 low-density lipoprotein particle receptor binding	12	5.40e-01	1.02e-01	7.31e-01
GO:0060612 adipose tissue development	23	3.97e-01	-1.02e-01	6.09e-01
GO:0043025 neuronal cell body	83	1.09e-01	1.02e-01	2.86e-01
GO:0003755 peptidyl-prolyl cis-trans isomerase activity	30	3.37e-01	-1.01e-01	5.48e-01
GO:1901673 regulation of mitotic spindle assembly	16	4.84e-01	-1.01e-01	6.82e-01
GO:0032588 trans-Golgi network membrane	25	3.82e-01	-1.01e-01	5.92e-01
GO:0098656 monoatomic anion transmembrane transport	18	4.58e-01	-1.01e-01	6.56e-01
GO:0006006 glucose metabolic process	26	3.73e-01	-1.01e-01	5.85e-01
GO:0030199 collagen fibril organization	31	3.31e-01	-1.01e-01	5.44e-01
GO:0044389 ubiquitin-like protein ligase binding	16	4.85e-01	1.01e-01	6.83e-01
GO:0005654 nucleoplasm	1531	1.35e-10	1.00e-01	1.25e-08
GO:0030496 midbody	100	8.51e-02	9.98e-02	2.44e-01
GO:0051781 positive regulation of cell division	12	5.50e-01	-9.97e-02	7.38e-01
GO:0019915 lipid storage	11	5.67e-01	9.97e-02	7.53e-01
GO:0008237 metallopeptidase activity	12	5.50e-01	9.96e-02	7.38e-01
GO:0010629 negative regulation of gene expression	102	8.34e-02	9.93e-02	2.41e-01
GO:0042327 positive regulation of phosphorylation	12	5.52e-01	-9.92e-02	7.39e-01
GO:0046580 negative regulation of Ras protein signal transduction	13	5.36e-01	-9.92e-02	7.26e-01
GO:0001666 response to hypoxia	50	2.26e-01	9.91e-02	4.39e-01
GO:0009982 pseudouridine synthase activity	12	5.53e-01	-9.90e-02	7.40e-01
GO:0030324 lung development	35	3.11e-01	-9.89e-02	5.26e-01
GO:0050853 B cell receptor signaling pathway	19	4.57e-01	9.86e-02	6.55e-01
GO:0001649 osteoblast differentiation	39	2.87e-01	9.85e-02	5.00e-01
GO:0044331 cell-cell adhesion mediated by cadherin	11	5.72e-01	-9.84e-02	7.55e-01
GO:0019706 protein-cysteine S-palmitoyltransferase activity	17	4.84e-01	-9.81e-02	6.82e-01
GO:0051087 protein-folding chaperone binding	55	2.09e-01	-9.80e-02	4.20e-01
GO:0005009 insulin receptor activity	14	5.29e-01	9.72e-02	7.21e-01
GO:0005689 U12-type spliceosomal complex	20	4.52e-01	-9.71e-02	6.52e-01
GO:0006268 DNA unwinding involved in DNA replication	14	5.31e-01	9.68e-02	7.22e-01
GO:0007628 adult walking behavior	13	5.46e-01	9.67e-02	7.36e-01
GO:0030326 embryonic limb morphogenesis	14	5.32e-01	9.66e-02	7.22e-01
GO:0000398 mRNA splicing, via spliceosome	87	1.20e-01	9.65e-02	3.00e-01
GO:0090110 COPII-coated vesicle cargo loading	10	5.97e-01	9.65e-02	7.69e-01
GO:0048701 embryonic cranial skeleton morphogenesis	13	5.48e-01	-9.63e-02	7.36e-01
GO:1990166 protein localization to site of double-strand break	10	6.01e-01	9.56e-02	7.72e-01
GO:0005635 nuclear envelope	76	1.51e-01	-9.53e-02	3.49e-01
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT	11	5.85e-01	-9.52e-02	7.63e-01
GO:0008092 cytoskeletal protein binding	15	5.24e-01	-9.51e-02	7.17e-01
GO:0051607 defense response to virus	55	2.25e-01	9.46e-02	4.39e-01
GO:0071549 cellular response to dexamethasone stimulus	11	5.88e-01	9.44e-02	7.63e-01
GO:0030501 positive regulation of bone mineralization	14	5.42e-01	-9.41e-02	7.33e-01
GO:0009617 response to bacterium	34	3.44e-01	-9.38e-02	5.54e-01
GO:0005685 U1 snRNP	12	5.74e-01	-9.38e-02	7.56e-01
GO:0030374 nuclear receptor coactivator activity	30	3.75e-01	9.37e-02	5.85e-01
GO:0005925 focal adhesion	113	8.62e-02	9.36e-02	2.46e-01
GO:0006915 apoptotic process	135	6.10e-02	-9.35e-02	1.97e-01
GO:0001764 neuron migration	37	3.25e-01	9.35e-02	5.38e-01
GO:0016757 glycosyltransferase activity	13	5.60e-01	-9.34e-02	7.46e-01
GO:0006882 intracellular zinc ion homeostasis	12	5.76e-01	-9.32e-02	7.58e-01
GO:0019838 growth factor binding	11	5.94e-01	9.29e-02	7.67e-01
GO:0019955 cytokine binding	11	5.94e-01	9.29e-02	7.67e-01
GO:0046872 metal ion binding	868	4.52e-06	9.27e-02	1.89e-04
GO:0048144 fibroblast proliferation	22	4.53e-01	-9.24e-02	6.53e-01
GO:0048009 insulin-like growth factor receptor signaling pathway	31	3.74e-01	9.23e-02	5.85e-01
GO:0007338 single fertilization	20	4.76e-01	-9.22e-02	6.74e-01
GO:0043596 nuclear replication fork	10	6.15e-01	-9.19e-02	7.80e-01
GO:0000226 microtubule cytoskeleton organization	68	1.92e-01	9.16e-02	4.03e-01
GO:0098978 glutamatergic synapse	230	1.70e-02	9.16e-02	8.12e-02
GO:0031175 neuron projection development	49	2.68e-01	9.15e-02	4.82e-01
GO:0120162 positive regulation of cold-induced thermogenesis	30	3.86e-01	-9.15e-02	5.96e-01
GO:0034451 centriolar satellite	73	1.78e-01	9.14e-02	3.83e-01
GO:0009636 response to toxic substance	15	5.40e-01	-9.13e-02	7.31e-01
GO:0006730 one-carbon metabolic process	13	5.69e-01	-9.11e-02	7.54e-01
GO:0030308 negative regulation of cell growth	42	3.08e-01	9.10e-02	5.21e-01
GO:0034394 protein localization to cell surface	17	5.16e-01	9.09e-02	7.13e-01
GO:0061436 establishment of skin barrier	13	5.71e-01	9.09e-02	7.54e-01
GO:0005975 carbohydrate metabolic process	49	2.74e-01	-9.03e-02	4.89e-01
GO:0042605 peptide antigen binding	10	6.21e-01	9.03e-02	7.83e-01
GO:0098793 presynapse	63	2.16e-01	9.02e-02	4.28e-01
GO:0032259 methylation	76	1.75e-01	-9.02e-02	3.80e-01
GO:0042274 ribosomal small subunit biogenesis	44	3.02e-01	-9.01e-02	5.14e-01
GO:0000902 cell morphogenesis	54	2.53e-01	9.00e-02	4.62e-01
GO:0007265 Ras protein signal transduction	37	3.44e-01	9.00e-02	5.54e-01
GO:0051965 positive regulation of synapse assembly	21	4.76e-01	8.98e-02	6.74e-01
GO:0005080 protein kinase C binding	17	5.22e-01	8.96e-02	7.17e-01
GO:0071944 cell periphery	12	5.91e-01	-8.96e-02	7.65e-01
GO:0001817 regulation of cytokine production	26	4.30e-01	-8.95e-02	6.36e-01
GO:0098655 monoatomic cation transmembrane transport	13	5.76e-01	-8.95e-02	7.58e-01
GO:0031410 cytoplasmic vesicle	105	1.14e-01	8.93e-02	2.91e-01
GO:0042593 glucose homeostasis	43	3.13e-01	-8.90e-02	5.26e-01
GO:0032040 small-subunit processome	59	2.38e-01	-8.90e-02	4.49e-01
GO:0006457 protein folding	81	1.68e-01	-8.87e-02	3.70e-01
GO:0007623 circadian rhythm	18	5.15e-01	8.86e-02	7.13e-01
GO:0098982 GABA-ergic synapse	29	4.09e-01	-8.85e-02	6.20e-01
GO:0005507 copper ion binding	23	4.63e-01	-8.84e-02	6.61e-01
GO:0010468 regulation of gene expression	57	2.49e-01	8.83e-02	4.60e-01
GO:0007612 learning	13	5.82e-01	8.81e-02	7.63e-01
GO:0007519 skeletal muscle tissue development	17	5.30e-01	-8.81e-02	7.21e-01
GO:0050870 positive regulation of T cell activation	14	5.69e-01	-8.80e-02	7.54e-01
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process	155	5.93e-02	-8.79e-02	1.93e-01
GO:0060391 positive regulation of SMAD protein signal transduction	11	6.14e-01	-8.79e-02	7.80e-01
GO:0098552 side of membrane	14	5.70e-01	-8.76e-02	7.54e-01
GO:0034976 response to endoplasmic reticulum stress	34	3.77e-01	-8.75e-02	5.87e-01
GO:0008361 regulation of cell size	13	5.85e-01	8.75e-02	7.63e-01
GO:0090543 Flemming body	14	5.71e-01	8.75e-02	7.54e-01
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation	29	4.16e-01	8.73e-02	6.25e-01
GO:0071346 cellular response to type II interferon	24	4.62e-01	8.68e-02	6.59e-01
GO:0071782 endoplasmic reticulum tubular network	12	6.03e-01	-8.67e-02	7.72e-01
GO:0050769 positive regulation of neurogenesis	12	6.03e-01	8.67e-02	7.72e-01
GO:0000082 G1/S transition of mitotic cell cycle	40	3.43e-01	8.66e-02	5.54e-01
GO:0007613 memory	28	4.28e-01	-8.66e-02	6.36e-01
GO:0007020 microtubule nucleation	14	5.77e-01	8.61e-02	7.58e-01
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway	19	5.17e-01	8.60e-02	7.13e-01
GO:0045668 negative regulation of osteoblast differentiation	27	4.40e-01	8.59e-02	6.45e-01
GO:0000151 ubiquitin ligase complex	48	3.04e-01	-8.58e-02	5.18e-01
GO:0036342 post-anal tail morphogenesis	11	6.23e-01	8.56e-02	7.84e-01
GO:0071363 cellular response to growth factor stimulus	19	5.21e-01	8.52e-02	7.17e-01
GO:0010975 regulation of neuron projection development	16	5.56e-01	8.50e-02	7.42e-01
GO:0007219 Notch signaling pathway	40	3.53e-01	8.50e-02	5.63e-01
GO:2000378 negative regulation of reactive oxygen species metabolic process	10	6.42e-01	-8.49e-02	7.96e-01
GO:0007608 sensory perception of smell	11	6.27e-01	-8.47e-02	7.87e-01
GO:1904294 positive regulation of ERAD pathway	10	6.44e-01	-8.44e-02	7.98e-01
GO:0000400 four-way junction DNA binding	14	5.86e-01	8.41e-02	7.63e-01
GO:0032587 ruffle membrane	41	3.52e-01	8.41e-02	5.63e-01
GO:0017124 SH3 domain binding	43	3.41e-01	-8.40e-02	5.52e-01
GO:0048854 brain morphogenesis	14	5.88e-01	-8.37e-02	7.63e-01
GO:0006486 protein glycosylation	44	3.38e-01	-8.36e-02	5.48e-01
GO:0001530 lipopolysaccharide binding	13	6.02e-01	-8.36e-02	7.72e-01
GO:0050728 negative regulation of inflammatory response	48	3.19e-01	-8.31e-02	5.32e-01
GO:0043001 Golgi to plasma membrane protein transport	21	5.11e-01	-8.28e-02	7.08e-01
GO:0005178 integrin binding	65	2.49e-01	-8.27e-02	4.60e-01
GO:0016042 lipid catabolic process	28	4.49e-01	-8.27e-02	6.51e-01
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway	42	3.57e-01	8.22e-02	5.67e-01
GO:0048147 negative regulation of fibroblast proliferation	14	5.96e-01	8.18e-02	7.69e-01
GO:0072542 protein phosphatase activator activity	10	6.55e-01	8.17e-02	8.07e-01
GO:0015701 bicarbonate transport	11	6.40e-01	-8.15e-02	7.95e-01
GO:1990904 ribonucleoprotein complex	105	1.50e-01	8.14e-02	3.49e-01
GO:0042391 regulation of membrane potential	11	6.41e-01	-8.12e-02	7.96e-01
GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway	15	5.87e-01	8.10e-02	7.63e-01
GO:0002250 adaptive immune response	21	5.21e-01	-8.08e-02	7.17e-01
GO:0031167 rRNA methylation	11	6.43e-01	-8.08e-02	7.97e-01
GO:0004867 serine-type endopeptidase inhibitor activity	21	5.24e-01	8.04e-02	7.17e-01
GO:0070300 phosphatidic acid binding	13	6.16e-01	8.04e-02	7.80e-01
GO:0007281 germ cell development	14	6.03e-01	8.02e-02	7.72e-01
GO:0006623 protein targeting to vacuole	11	6.48e-01	7.96e-02	8.01e-01
GO:0046326 positive regulation of D-glucose import	14	6.06e-01	-7.95e-02	7.75e-01
GO:0042098 T cell proliferation	16	5.83e-01	7.93e-02	7.63e-01
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	28	4.69e-01	-7.91e-02	6.66e-01
GO:0002244 hematopoietic progenitor cell differentiation	35	4.20e-01	7.88e-02	6.30e-01
GO:0044322 endoplasmic reticulum quality control compartment	11	6.52e-01	-7.85e-02	8.05e-01
GO:0038023 signaling receptor activity	41	3.86e-01	7.82e-02	5.96e-01
GO:0006629 lipid metabolic process	52	3.31e-01	-7.79e-02	5.44e-01
GO:0005901 caveola	28	4.76e-01	-7.79e-02	6.74e-01
GO:0051649 establishment of localization in cell	38	4.08e-01	-7.76e-02	6.19e-01
GO:0030225 macrophage differentiation	11	6.57e-01	-7.75e-02	8.09e-01
GO:0097225 sperm midpiece	15	6.04e-01	7.74e-02	7.72e-01
GO:0031982 vesicle	27	4.87e-01	7.73e-02	6.84e-01
GO:0004222 metalloendopeptidase activity	50	3.45e-01	7.72e-02	5.55e-01
GO:0005615 extracellular space	399	8.50e-03	-7.71e-02	5.03e-02
GO:0010506 regulation of autophagy	26	4.98e-01	7.68e-02	6.95e-01
GO:0007080 mitotic metaphase chromosome alignment	23	5.27e-01	-7.62e-02	7.19e-01
GO:0004864 protein phosphatase inhibitor activity	13	6.34e-01	-7.62e-02	7.91e-01
GO:0009408 response to heat	19	5.67e-01	-7.59e-02	7.53e-01
GO:0032731 positive regulation of interleukin-1 beta production	12	6.49e-01	7.58e-02	8.02e-01
GO:0051301 cell division	144	1.18e-01	7.56e-02	2.97e-01
GO:0032760 positive regulation of tumor necrosis factor production	34	4.47e-01	7.54e-02	6.51e-01
GO:0030593 neutrophil chemotaxis	13	6.38e-01	7.54e-02	7.94e-01
GO:0000939 inner kinetochore	10	6.80e-01	7.54e-02	8.24e-01
GO:0016853 isomerase activity	19	5.70e-01	7.52e-02	7.54e-01
GO:0000287 magnesium ion binding	149	1.14e-01	-7.51e-02	2.91e-01
GO:0006493 protein O-linked glycosylation	28	4.92e-01	-7.51e-02	6.88e-01
GO:0061744 motor behavior	16	6.03e-01	7.50e-02	7.72e-01
GO:0031398 positive regulation of protein ubiquitination	40	4.14e-01	-7.46e-02	6.24e-01
GO:0007166 cell surface receptor signaling pathway	40	4.15e-01	7.46e-02	6.24e-01
GO:0030838 positive regulation of actin filament polymerization	27	5.03e-01	-7.44e-02	7.00e-01
GO:0000922 spindle pole	68	2.91e-01	7.42e-02	5.03e-01
GO:0001654 eye development	17	5.97e-01	-7.41e-02	7.69e-01
GO:0007286 spermatid development	25	5.21e-01	-7.41e-02	7.17e-01
GO:0001568 blood vessel development	18	5.86e-01	7.41e-02	7.63e-01
GO:0035025 positive regulation of Rho protein signal transduction	10	6.86e-01	-7.39e-02	8.30e-01
GO:0042626 ATPase-coupled transmembrane transporter activity	16	6.09e-01	7.38e-02	7.77e-01
GO:0033192 calmodulin-dependent protein phosphatase activity	16	6.10e-01	-7.36e-02	7.78e-01
GO:0007165 signal transduction	263	4.08e-02	7.35e-02	1.50e-01
GO:0016460 myosin II complex	12	6.60e-01	7.33e-02	8.12e-01
GO:0006352 DNA-templated transcription initiation	11	6.74e-01	7.32e-02	8.20e-01
GO:0016740 transferase activity	23	5.44e-01	-7.31e-02	7.34e-01
GO:0006893 Golgi to plasma membrane transport	19	5.81e-01	7.31e-02	7.62e-01
GO:0007229 integrin-mediated signaling pathway	44	4.04e-01	7.27e-02	6.17e-01
GO:0070536 protein K63-linked deubiquitination	16	6.16e-01	7.25e-02	7.80e-01
GO:0007368 determination of left/right symmetry	28	5.07e-01	-7.25e-02	7.04e-01
GO:0010608 post-transcriptional regulation of gene expression	11	6.78e-01	7.24e-02	8.24e-01
GO:0097190 apoptotic signaling pathway	20	5.77e-01	7.21e-02	7.58e-01
GO:0050714 positive regulation of protein secretion	19	5.87e-01	7.21e-02	7.63e-01
GO:0040018 positive regulation of multicellular organism growth	16	6.18e-01	7.20e-02	7.81e-01
GO:0032418 lysosome localization	23	5.50e-01	-7.20e-02	7.38e-01
GO:0000159 protein phosphatase type 2A complex	12	6.66e-01	-7.20e-02	8.16e-01
GO:0007517 muscle organ development	12	6.68e-01	-7.16e-02	8.17e-01
GO:0020037 heme binding	50	3.83e-01	-7.13e-02	5.93e-01
GO:0048786 presynaptic active zone	10	6.97e-01	7.11e-02	8.36e-01
GO:0003676 nucleic acid binding	106	2.09e-01	7.07e-02	4.20e-01
GO:0140664 ATP-dependent DNA damage sensor activity	14	6.47e-01	7.06e-02	8.01e-01
GO:0048012 hepatocyte growth factor receptor signaling pathway	17	6.15e-01	7.05e-02	7.80e-01
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II	12	6.73e-01	7.04e-02	8.20e-01
GO:0006783 heme biosynthetic process	10	7.01e-01	-7.01e-02	8.38e-01
GO:0031573 mitotic intra-S DNA damage checkpoint signaling	11	6.88e-01	-7.00e-02	8.30e-01
GO:0048008 platelet-derived growth factor receptor signaling pathway	17	6.18e-01	-6.99e-02	7.81e-01
GO:0005801 cis-Golgi network	28	5.24e-01	-6.96e-02	7.17e-01
GO:0047496 vesicle transport along microtubule	11	6.91e-01	6.91e-02	8.31e-01
GO:0005814 centriole	92	2.53e-01	6.90e-02	4.62e-01
GO:0051402 neuron apoptotic process	42	4.41e-01	6.87e-02	6.46e-01
GO:0097191 extrinsic apoptotic signaling pathway	20	5.97e-01	6.83e-02	7.69e-01
GO:0000712 resolution of meiotic recombination intermediates	14	6.61e-01	6.77e-02	8.12e-01
GO:0141198 protein branched polyubiquitination	13	6.73e-01	6.75e-02	8.20e-01
GO:0034244 negative regulation of transcription elongation by RNA polymerase II	13	6.74e-01	6.74e-02	8.20e-01
GO:0035725 sodium ion transmembrane transport	48	4.20e-01	-6.73e-02	6.30e-01
GO:0036297 interstrand cross-link repair	24	5.69e-01	-6.72e-02	7.54e-01
GO:0004181 metallocarboxypeptidase activity	11	7.01e-01	6.70e-02	8.38e-01
GO:0070063 RNA polymerase binding	12	6.88e-01	6.70e-02	8.30e-01
GO:0032991 protein-containing complex	207	9.80e-02	6.69e-02	2.68e-01
GO:0071897 DNA biosynthetic process	12	6.89e-01	6.67e-02	8.30e-01
GO:0006909 phagocytosis	23	5.80e-01	-6.67e-02	7.61e-01
GO:0016779 nucleotidyltransferase activity	10	7.16e-01	-6.65e-02	8.49e-01
GO:0007254 JNK cascade	26	5.58e-01	6.64e-02	7.44e-01
GO:0051225 spindle assembly	21	5.99e-01	-6.63e-02	7.71e-01
GO:0035176 social behavior	17	6.38e-01	6.60e-02	7.94e-01
GO:0004714 transmembrane receptor protein tyrosine kinase activity	14	6.71e-01	-6.57e-02	8.20e-01
GO:0044183 protein folding chaperone	21	6.03e-01	-6.56e-02	7.72e-01
GO:0010839 negative regulation of keratinocyte proliferation	14	6.71e-01	-6.55e-02	8.20e-01
GO:0008217 regulation of blood pressure	20	6.13e-01	6.54e-02	7.80e-01
GO:0046540 U4/U6 x U5 tri-snRNP complex	23	5.88e-01	6.53e-02	7.63e-01
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis	14	6.73e-01	-6.52e-02	8.20e-01
GO:0005515 protein binding	90	2.86e-01	6.51e-02	5.00e-01
GO:0043014 alpha-tubulin binding	23	5.89e-01	6.51e-02	7.64e-01
GO:0005770 late endosome	74	3.37e-01	-6.46e-02	5.48e-01
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process	19	6.28e-01	-6.43e-02	7.88e-01
GO:2000811 negative regulation of anoikis	10	7.25e-01	6.42e-02	8.54e-01
GO:0030970 retrograde protein transport, ER to cytosol	12	7.00e-01	-6.42e-02	8.38e-01
GO:0046982 protein heterodimerization activity	131	2.05e-01	-6.42e-02	4.17e-01
GO:0042645 mitochondrial nucleoid	37	5.01e-01	6.40e-02	6.97e-01
GO:0099175 regulation of postsynapse organization	20	6.21e-01	6.39e-02	7.83e-01
GO:0050821 protein stabilization	109	2.51e-01	-6.38e-02	4.61e-01
GO:0031648 protein destabilization	32	5.33e-01	6.37e-02	7.23e-01
GO:0004722 protein serine/threonine phosphatase activity	33	5.27e-01	-6.36e-02	7.19e-01
GO:1904262 negative regulation of TORC1 signaling	28	5.60e-01	-6.36e-02	7.46e-01
GO:0014069 postsynaptic density	97	2.81e-01	6.35e-02	4.95e-01
GO:0007214 gamma-aminobutyric acid signaling pathway	10	7.28e-01	6.34e-02	8.57e-01
GO:0030170 pyridoxal phosphate binding	33	5.29e-01	-6.33e-02	7.21e-01
GO:0005794 Golgi apparatus	464	2.04e-02	-6.32e-02	9.14e-02
GO:0002682 regulation of immune system process	11	7.17e-01	-6.31e-02	8.50e-01
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway	31	5.47e-01	6.25e-02	7.36e-01
GO:0045444 fat cell differentiation	44	4.74e-01	6.25e-02	6.72e-01
GO:0045499 chemorepellent activity	17	6.57e-01	-6.22e-02	8.09e-01
GO:0010467 gene expression	81	3.34e-01	6.21e-02	5.47e-01
GO:0045111 intermediate filament cytoskeleton	23	6.07e-01	6.20e-02	7.75e-01
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process	43	4.82e-01	-6.19e-02	6.81e-01
GO:0045505 dynein intermediate chain binding	16	6.68e-01	-6.19e-02	8.17e-01
GO:0043123 positive regulation of canonical NF-kappaB signal transduction	75	3.55e-01	6.18e-02	5.65e-01
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding	21	6.24e-01	6.18e-02	7.85e-01
GO:0001958 endochondral ossification	15	6.79e-01	-6.17e-02	8.24e-01
GO:2001235 positive regulation of apoptotic signaling pathway	17	6.60e-01	-6.17e-02	8.12e-01
GO:0055038 recycling endosome membrane	43	4.91e-01	6.07e-02	6.88e-01
GO:0000774 adenyl-nucleotide exchange factor activity	12	7.16e-01	6.07e-02	8.49e-01
GO:0035091 phosphatidylinositol binding	74	3.68e-01	6.06e-02	5.79e-01
GO:0007098 centrosome cycle	17	6.66e-01	6.04e-02	8.16e-01
GO:0070588 calcium ion transmembrane transport	46	4.79e-01	-6.04e-02	6.77e-01
GO:0051289 protein homotetramerization	35	5.37e-01	-6.03e-02	7.28e-01
GO:0051457 maintenance of protein location in nucleus	10	7.43e-01	5.99e-02	8.69e-01
GO:0038062 protein tyrosine kinase collagen receptor activity	13	7.10e-01	5.96e-02	8.46e-01
GO:0035791 platelet-derived growth factor receptor-beta signaling pathway	15	6.90e-01	5.94e-02	8.31e-01
GO:0004252 serine-type endopeptidase activity	52	4.59e-01	-5.93e-02	6.57e-01
GO:0045862 positive regulation of proteolysis	12	7.22e-01	-5.92e-02	8.53e-01
GO:0030507 spectrin binding	12	7.23e-01	-5.92e-02	8.53e-01
GO:0050727 regulation of inflammatory response	26	6.01e-01	-5.92e-02	7.72e-01
GO:0097194 execution phase of apoptosis	10	7.46e-01	5.92e-02	8.71e-01
GO:0048813 dendrite morphogenesis	20	6.50e-01	-5.86e-02	8.03e-01
GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	77	3.75e-01	5.86e-02	5.85e-01
GO:0042177 negative regulation of protein catabolic process	23	6.29e-01	5.82e-02	7.88e-01
GO:0045747 positive regulation of Notch signaling pathway	23	6.30e-01	5.81e-02	7.88e-01
GO:0030097 hemopoiesis	25	6.17e-01	5.78e-02	7.81e-01
GO:0006508 proteolysis	172	1.92e-01	5.78e-02	4.03e-01
GO:0043231 intracellular membrane-bounded organelle	113	2.93e-01	5.73e-02	5.04e-01
GO:0005680 anaphase-promoting complex	13	7.21e-01	-5.73e-02	8.53e-01
GO:0009986 cell surface	182	1.87e-01	5.69e-02	3.96e-01
GO:0006874 intracellular calcium ion homeostasis	36	5.55e-01	5.68e-02	7.42e-01
GO:0070062 extracellular exosome	38	5.47e-01	5.65e-02	7.36e-01
GO:0032496 response to lipopolysaccharide	37	5.54e-01	5.63e-02	7.41e-01
GO:0008083 growth factor activity	37	5.57e-01	5.59e-02	7.42e-01
GO:0016925 protein sumoylation	19	6.74e-01	5.57e-02	8.20e-01
GO:0034605 cellular response to heat	16	7.04e-01	5.49e-02	8.41e-01
GO:0004672 protein kinase activity	64	4.48e-01	5.49e-02	6.51e-01
GO:0007218 neuropeptide signaling pathway	16	7.07e-01	5.43e-02	8.44e-01
GO:0001669 acrosomal vesicle	26	6.32e-01	-5.43e-02	7.90e-01
GO:0009615 response to virus	29	6.14e-01	-5.41e-02	7.80e-01
GO:0071407 cellular response to organic cyclic compound	11	7.57e-01	5.39e-02	8.75e-01
GO:0051642 centrosome localization	14	7.28e-01	-5.37e-02	8.57e-01
GO:0005791 rough endoplasmic reticulum	12	7.48e-01	5.36e-02	8.72e-01
GO:0030246 carbohydrate binding	39	5.64e-01	-5.34e-02	7.50e-01
GO:0051497 negative regulation of stress fiber assembly	18	6.95e-01	5.34e-02	8.34e-01
GO:0043616 keratinocyte proliferation	11	7.60e-01	-5.32e-02	8.78e-01
GO:0043687 post-translational protein modification	19	6.89e-01	5.30e-02	8.30e-01
GO:0030674 protein-macromolecule adaptor activity	73	4.34e-01	-5.30e-02	6.41e-01
GO:0046847 filopodium assembly	11	7.61e-01	5.29e-02	8.78e-01
GO:0032154 cleavage furrow	28	6.28e-01	5.29e-02	7.88e-01
GO:0005769 early endosome	141	2.80e-01	-5.28e-02	4.95e-01
GO:0046627 negative regulation of insulin receptor signaling pathway	16	7.15e-01	5.27e-02	8.49e-01
GO:0072583 clathrin-dependent endocytosis	19	6.93e-01	-5.23e-02	8.33e-01
GO:0008344 adult locomotory behavior	23	6.65e-01	5.21e-02	8.16e-01
GO:0015630 microtubule cytoskeleton	69	4.55e-01	5.21e-02	6.55e-01
GO:0046513 ceramide biosynthetic process	19	6.95e-01	-5.20e-02	8.34e-01
GO:0004521 RNA endonuclease activity	20	6.88e-01	-5.19e-02	8.30e-01
GO:0006284 base-excision repair	17	7.12e-01	5.18e-02	8.47e-01
GO:0006509 membrane protein ectodomain proteolysis	15	7.29e-01	5.17e-02	8.57e-01
GO:0006368 transcription elongation by RNA polymerase II	24	6.64e-01	5.13e-02	8.15e-01
GO:0016020 membrane	942	8.44e-03	-5.13e-02	5.01e-02
GO:0045722 positive regulation of gluconeogenesis	10	7.80e-01	-5.11e-02	8.89e-01
GO:0060079 excitatory postsynaptic potential	15	7.32e-01	5.10e-02	8.60e-01
GO:0090141 positive regulation of mitochondrial fission	16	7.24e-01	-5.09e-02	8.54e-01
GO:0000776 kinetochore	90	4.05e-01	5.08e-02	6.18e-01
GO:0006897 endocytosis	91	4.09e-01	5.01e-02	6.20e-01
GO:0016055 Wnt signaling pathway	77	4.49e-01	4.99e-02	6.51e-01
GO:0006310 DNA recombination	23	6.80e-01	4.98e-02	8.24e-01
GO:0045821 positive regulation of glycolytic process	10	7.85e-01	4.97e-02	8.93e-01
GO:0045202 synapse	162	2.77e-01	-4.96e-02	4.92e-01
GO:0046676 negative regulation of insulin secretion	10	7.88e-01	4.92e-02	8.95e-01
GO:0007186 G protein-coupled receptor signaling pathway	90	4.23e-01	4.90e-02	6.31e-01
GO:0008285 negative regulation of cell population proliferation	116	3.70e-01	4.83e-02	5.81e-01
GO:0034097 response to cytokine	12	7.72e-01	-4.82e-02	8.86e-01
GO:0050699 WW domain binding	11	7.83e-01	-4.80e-02	8.91e-01
GO:0031547 brain-derived neurotrophic factor receptor signaling pathway	14	7.56e-01	4.79e-02	8.75e-01
GO:0005604 basement membrane	43	5.88e-01	4.78e-02	7.63e-01
GO:0016239 positive regulation of macroautophagy	17	7.34e-01	4.77e-02	8.60e-01
GO:0099523 presynaptic cytosol	11	7.85e-01	-4.75e-02	8.93e-01
GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	35	6.33e-01	4.67e-02	7.90e-01
GO:0038109 Kit signaling pathway	14	7.63e-01	-4.65e-02	8.80e-01
GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels	16	7.48e-01	4.64e-02	8.72e-01
GO:0019216 regulation of lipid metabolic process	10	8.01e-01	-4.61e-02	9.00e-01
GO:0008076 voltage-gated potassium channel complex	18	7.36e-01	-4.59e-02	8.63e-01
GO:0044877 protein-containing complex binding	105	4.22e-01	4.55e-02	6.30e-01
GO:0042470 melanosome	27	6.83e-01	-4.54e-02	8.28e-01
GO:0009267 cellular response to starvation	48	5.87e-01	4.53e-02	7.63e-01
GO:0061630 ubiquitin protein ligase activity	176	3.01e-01	4.53e-02	5.13e-01
GO:0060218 hematopoietic stem cell differentiation	11	7.95e-01	4.53e-02	8.98e-01
GO:0019933 cAMP-mediated signaling	13	7.77e-01	4.53e-02	8.89e-01
GO:0036064 ciliary basal body	103	4.28e-01	-4.52e-02	6.36e-01
GO:0048471 perinuclear region of cytoplasm	287	1.90e-01	4.51e-02	4.00e-01
GO:0061564 axon development	13	7.80e-01	-4.48e-02	8.89e-01
GO:0045740 positive regulation of DNA replication	11	7.97e-01	4.48e-02	8.99e-01
GO:0030317 flagellated sperm motility	27	6.89e-01	-4.45e-02	8.30e-01
GO:0005730 nucleolus	442	1.13e-01	4.42e-02	2.90e-01
GO:2000786 positive regulation of autophagosome assembly	14	7.75e-01	-4.41e-02	8.88e-01
GO:0005774 vacuolar membrane	10	8.09e-01	-4.41e-02	9.05e-01
GO:0005198 structural molecule activity	38	6.40e-01	-4.39e-02	7.95e-01
GO:0048487 beta-tubulin binding	22	7.22e-01	4.39e-02	8.53e-01
GO:0004930 G protein-coupled receptor activity	54	5.78e-01	4.38e-02	7.58e-01
GO:0031593 polyubiquitin modification-dependent protein binding	19	7.41e-01	4.38e-02	8.68e-01
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	11	8.01e-01	4.38e-02	9.00e-01
GO:0051453 regulation of intracellular pH	15	7.69e-01	-4.38e-02	8.84e-01
GO:0006935 chemotaxis	15	7.70e-01	-4.37e-02	8.84e-01
GO:0005903 brush border	18	7.50e-01	-4.34e-02	8.72e-01
GO:0032481 positive regulation of type I interferon production	18	7.50e-01	4.34e-02	8.72e-01
GO:0040014 regulation of multicellular organism growth	12	7.95e-01	4.32e-02	8.98e-01
GO:0035925 mRNA 3’-UTR AU-rich region binding	13	7.90e-01	-4.27e-02	8.96e-01
GO:0010508 positive regulation of autophagy	39	6.44e-01	-4.27e-02	7.98e-01
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway	28	6.97e-01	-4.25e-02	8.36e-01
GO:0060041 retina development in camera-type eye	20	7.44e-01	4.22e-02	8.70e-01
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway	12	8.01e-01	-4.21e-02	9.00e-01
GO:0031464 Cul4A-RING E3 ubiquitin ligase complex	10	8.18e-01	-4.21e-02	9.12e-01
GO:0005010 insulin-like growth factor receptor activity	13	7.93e-01	4.21e-02	8.98e-01
GO:0043065 positive regulation of apoptotic process	121	4.25e-01	4.20e-02	6.34e-01
GO:0046677 response to antibiotic	13	7.94e-01	4.18e-02	8.98e-01
GO:0072344 rescue of stalled ribosome	26	7.14e-01	-4.15e-02	8.49e-01
GO:0043029 T cell homeostasis	13	7.95e-01	4.15e-02	8.98e-01
GO:0042803 protein homodimerization activity	371	1.72e-01	-4.15e-02	3.76e-01
GO:0019221 cytokine-mediated signaling pathway	45	6.32e-01	-4.13e-02	7.90e-01
GO:0016324 apical plasma membrane	121	4.34e-01	4.13e-02	6.40e-01
GO:0005829 cytosol	2011	3.10e-03	4.11e-02	2.58e-02
GO:0016567 protein ubiquitination	155	3.81e-01	4.09e-02	5.92e-01
GO:0045721 negative regulation of gluconeogenesis	10	8.23e-01	-4.07e-02	9.16e-01
GO:0005019 platelet-derived growth factor beta-receptor activity	13	8.00e-01	4.07e-02	9.00e-01
GO:0042147 retrograde transport, endosome to Golgi	50	6.20e-01	-4.06e-02	7.83e-01
GO:0060271 cilium assembly	124	4.36e-01	-4.06e-02	6.42e-01
GO:0048870 cell motility	12	8.08e-01	4.05e-02	9.04e-01
GO:0007032 endosome organization	28	7.12e-01	4.04e-02	8.47e-01
GO:0031297 replication fork processing	26	7.24e-01	4.00e-02	8.54e-01
GO:0043130 ubiquitin binding	61	5.90e-01	3.99e-02	7.64e-01
GO:0007224 smoothened signaling pathway	50	6.30e-01	3.94e-02	7.88e-01
GO:0030335 positive regulation of cell migration	106	4.86e-01	3.92e-02	6.84e-01
GO:1990756 ubiquitin-like ligase-substrate adaptor activity	71	5.71e-01	-3.89e-02	7.54e-01
GO:0009411 response to UV	23	7.50e-01	-3.84e-02	8.72e-01
GO:0019722 calcium-mediated signaling	31	7.13e-01	3.82e-02	8.48e-01
GO:0035556 intracellular signal transduction	183	3.74e-01	3.82e-02	5.85e-01
GO:0001772 immunological synapse	23	7.52e-01	-3.80e-02	8.74e-01
GO:0030217 T cell differentiation	19	7.75e-01	3.80e-02	8.88e-01
GO:0044297 cell body	24	7.48e-01	3.79e-02	8.72e-01
GO:0003180 aortic valve morphogenesis	11	8.30e-01	3.74e-02	9.18e-01
GO:0070527 platelet aggregation	15	8.03e-01	-3.73e-02	9.01e-01
GO:0010008 endosome membrane	86	5.56e-01	-3.68e-02	7.42e-01
GO:0044344 cellular response to fibroblast growth factor stimulus	10	8.41e-01	-3.66e-02	9.22e-01
GO:0071949 FAD binding	27	7.43e-01	-3.65e-02	8.69e-01
GO:0045121 membrane raft	74	5.88e-01	-3.64e-02	7.64e-01
GO:0051017 actin filament bundle assembly	13	8.21e-01	-3.63e-02	9.14e-01
GO:0005813 centrosome	343	2.54e-01	3.60e-02	4.62e-01
GO:0005506 iron ion binding	64	6.20e-01	3.58e-02	7.83e-01
GO:0007420 brain development	76	5.90e-01	3.58e-02	7.64e-01
GO:0005006 epidermal growth factor receptor activity	14	8.17e-01	-3.58e-02	9.12e-01
GO:0045824 negative regulation of innate immune response	16	8.05e-01	-3.57e-02	9.02e-01
GO:0006955 immune response	43	6.86e-01	3.56e-02	8.30e-01
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway	13	8.24e-01	-3.56e-02	9.16e-01
GO:0006364 rRNA processing	65	6.22e-01	-3.54e-02	7.83e-01
GO:0008154 actin polymerization or depolymerization	11	8.40e-01	-3.51e-02	9.22e-01
GO:0034504 protein localization to nucleus	20	7.86e-01	3.51e-02	8.93e-01
GO:0035269 protein O-linked mannosylation	13	8.27e-01	3.49e-02	9.16e-01
GO:0062023 collagen-containing extracellular matrix	71	6.13e-01	-3.47e-02	7.80e-01
GO:0051059 NF-kappaB binding	22	7.79e-01	3.46e-02	8.89e-01
GO:0050729 positive regulation of inflammatory response	22	7.80e-01	-3.44e-02	8.89e-01
GO:0035102 PRC1 complex	12	8.38e-01	3.40e-02	9.22e-01
GO:0005657 replication fork	20	7.94e-01	-3.37e-02	8.98e-01
GO:0043153 entrainment of circadian clock by photoperiod	13	8.33e-01	-3.37e-02	9.20e-01
GO:0007173 epidermal growth factor receptor signaling pathway	38	7.22e-01	3.33e-02	8.53e-01
GO:0001786 phosphatidylserine binding	25	7.76e-01	-3.29e-02	8.89e-01
GO:0000175 3’-5’-RNA exonuclease activity	21	7.95e-01	3.28e-02	8.98e-01
GO:1903078 positive regulation of protein localization to plasma membrane	21	7.95e-01	3.27e-02	8.98e-01
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding	12	8.45e-01	-3.26e-02	9.26e-01
GO:0001503 ossification	25	7.79e-01	3.24e-02	8.89e-01
GO:0006400 tRNA modification	11	8.54e-01	3.21e-02	9.32e-01
GO:0000502 proteasome complex	13	8.42e-01	-3.20e-02	9.22e-01
GO:0044325 transmembrane transporter binding	54	6.87e-01	3.18e-02	8.30e-01
GO:0006096 glycolytic process	23	7.93e-01	3.16e-02	8.98e-01
GO:0071479 cellular response to ionizing radiation	22	7.99e-01	3.14e-02	9.00e-01
GO:0008543 fibroblast growth factor receptor signaling pathway	35	7.54e-01	-3.06e-02	8.74e-01
GO:0001974 blood vessel remodeling	17	8.28e-01	3.05e-02	9.16e-01
GO:0001755 neural crest cell migration	24	7.98e-01	3.02e-02	8.99e-01
GO:0019888 protein phosphatase regulator activity	16	8.34e-01	3.02e-02	9.20e-01
GO:0007040 lysosome organization	33	7.66e-01	-3.00e-02	8.82e-01
GO:0005795 Golgi stack	18	8.26e-01	3.00e-02	9.16e-01
GO:0005007 fibroblast growth factor receptor activity	13	8.52e-01	-2.99e-02	9.30e-01
GO:0071260 cellular response to mechanical stimulus	23	8.05e-01	-2.98e-02	9.02e-01
GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction	22	8.10e-01	2.97e-02	9.05e-01
GO:0030509 BMP signaling pathway	37	7.57e-01	2.94e-02	8.75e-01
GO:0009968 negative regulation of signal transduction	14	8.50e-01	-2.93e-02	9.28e-01
GO:0005576 extracellular region	237	4.41e-01	-2.91e-02	6.46e-01
GO:0045732 positive regulation of protein catabolic process	46	7.34e-01	-2.90e-02	8.60e-01
GO:0005737 cytoplasm	2171	3.32e-02	2.87e-02	1.29e-01
GO:0043204 perikaryon	35	7.70e-01	2.86e-02	8.84e-01
GO:0042474 middle ear morphogenesis	10	8.77e-01	-2.84e-02	9.47e-01
GO:0043005 neuron projection	95	6.35e-01	-2.82e-02	7.91e-01
GO:0001935 endothelial cell proliferation	12	8.67e-01	2.79e-02	9.42e-01
GO:0060828 regulation of canonical Wnt signaling pathway	18	8.39e-01	2.78e-02	9.22e-01
GO:0001676 long-chain fatty acid metabolic process	11	8.74e-01	-2.77e-02	9.47e-01
GO:0042632 cholesterol homeostasis	39	7.67e-01	-2.75e-02	8.82e-01
GO:0007288 sperm axoneme assembly	18	8.41e-01	-2.74e-02	9.22e-01
GO:0007339 binding of sperm to zona pellucida	11	8.75e-01	2.74e-02	9.47e-01
GO:2000300 regulation of synaptic vesicle exocytosis	18	8.41e-01	2.72e-02	9.22e-01
GO:0031290 retinal ganglion cell axon guidance	11	8.77e-01	2.70e-02	9.47e-01
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity	20	8.35e-01	-2.69e-02	9.21e-01
GO:0009897 external side of plasma membrane	108	6.36e-01	-2.64e-02	7.92e-01
GO:0051085 chaperone cofactor-dependent protein refolding	23	8.28e-01	-2.63e-02	9.16e-01
GO:0051865 protein autoubiquitination	38	7.80e-01	-2.63e-02	8.89e-01
GO:0005637 nuclear inner membrane	24	8.24e-01	2.62e-02	9.16e-01
GO:0007179 transforming growth factor beta receptor signaling pathway	48	7.54e-01	-2.61e-02	8.74e-01
GO:0001819 positive regulation of cytokine production	13	8.71e-01	-2.61e-02	9.45e-01
GO:0000775 chromosome, centromeric region	31	8.03e-01	2.59e-02	9.01e-01
GO:0043022 ribosome binding	46	7.62e-01	-2.59e-02	8.78e-01
GO:0048704 embryonic skeletal system morphogenesis	18	8.50e-01	2.58e-02	9.28e-01
GO:0030215 semaphorin receptor binding	10	8.88e-01	-2.58e-02	9.51e-01
GO:0007015 actin filament organization	70	7.09e-01	-2.58e-02	8.46e-01
GO:0072659 protein localization to plasma membrane	75	7.05e-01	-2.53e-02	8.42e-01
GO:0099171 presynaptic modulation of chemical synaptic transmission	11	8.85e-01	2.52e-02	9.50e-01
GO:0006605 protein targeting	18	8.54e-01	-2.50e-02	9.32e-01
GO:0007274 neuromuscular synaptic transmission	12	8.81e-01	-2.50e-02	9.49e-01
GO:0016323 basolateral plasma membrane	94	6.78e-01	2.48e-02	8.24e-01
GO:0008201 heparin binding	57	7.47e-01	-2.47e-02	8.72e-01
GO:0042802 identical protein binding	659	2.89e-01	2.44e-02	5.01e-01
GO:0032024 positive regulation of insulin secretion	21	8.47e-01	-2.43e-02	9.27e-01
GO:0007029 endoplasmic reticulum organization	16	8.67e-01	2.42e-02	9.42e-01
GO:0030198 extracellular matrix organization	76	7.17e-01	-2.40e-02	8.50e-01
GO:0007626 locomotory behavior	26	8.33e-01	2.39e-02	9.20e-01
GO:0019900 kinase binding	47	7.77e-01	2.39e-02	8.89e-01
GO:0061608 nuclear import signal receptor activity	14	8.77e-01	2.38e-02	9.47e-01
GO:0030234 enzyme regulator activity	14	8.78e-01	2.37e-02	9.47e-01
GO:0042552 myelination	28	8.29e-01	-2.35e-02	9.18e-01
GO:0008284 positive regulation of cell population proliferation	156	6.14e-01	2.34e-02	7.80e-01
GO:0140359 ABC-type transporter activity	10	8.99e-01	2.32e-02	9.58e-01
GO:0031145 anaphase-promoting complex-dependent catabolic process	14	8.81e-01	2.31e-02	9.49e-01
GO:0005008 hepatocyte growth factor receptor activity	13	8.86e-01	2.29e-02	9.50e-01
GO:1905515 non-motile cilium assembly	39	8.06e-01	-2.28e-02	9.02e-01
GO:0005886 plasma membrane	1513	1.47e-01	2.28e-02	3.44e-01
GO:0031418 L-ascorbic acid binding	14	8.85e-01	-2.24e-02	9.50e-01
GO:0008340 determination of adult lifespan	21	8.61e-01	-2.20e-02	9.39e-01
GO:0001736 establishment of planar polarity	12	8.95e-01	-2.19e-02	9.57e-01
GO:0044782 cilium organization	12	8.96e-01	-2.18e-02	9.57e-01
GO:0071356 cellular response to tumor necrosis factor	37	8.19e-01	2.18e-02	9.13e-01
GO:0031625 ubiquitin protein ligase binding	171	6.26e-01	-2.17e-02	7.86e-01
GO:1990830 cellular response to leukemia inhibitory factor	66	7.64e-01	2.13e-02	8.81e-01
GO:0030168 platelet activation	11	9.05e-01	-2.08e-02	9.60e-01
GO:0005834 heterotrimeric G-protein complex	19	8.76e-01	-2.08e-02	9.47e-01
GO:0071364 cellular response to epidermal growth factor stimulus	19	8.77e-01	2.05e-02	9.47e-01
GO:0030742 GTP-dependent protein binding	13	8.99e-01	2.04e-02	9.58e-01
GO:0034450 ubiquitin-ubiquitin ligase activity	12	9.03e-01	2.03e-02	9.59e-01
GO:0048018 receptor ligand activity	17	8.85e-01	2.02e-02	9.50e-01
GO:0071300 cellular response to retinoic acid	17	8.85e-01	2.02e-02	9.50e-01
GO:0007283 spermatogenesis	100	7.33e-01	1.98e-02	8.60e-01
GO:0006954 inflammatory response	83	7.56e-01	1.98e-02	8.75e-01
GO:0048027 mRNA 5’-UTR binding	19	8.82e-01	1.97e-02	9.50e-01
GO:1901223 negative regulation of non-canonical NF-kappaB signal transduction	14	9.00e-01	1.94e-02	9.59e-01
GO:0046332 SMAD binding	23	8.73e-01	1.93e-02	9.47e-01
GO:0008289 lipid binding	44	8.27e-01	-1.91e-02	9.16e-01
GO:0032880 regulation of protein localization	41	8.34e-01	1.89e-02	9.20e-01
GO:0031462 Cul2-RING ubiquitin ligase complex	15	9.00e-01	-1.87e-02	9.59e-01
GO:1902476 chloride transmembrane transport	38	8.49e-01	1.78e-02	9.28e-01
GO:0032755 positive regulation of interleukin-6 production	32	8.65e-01	1.74e-02	9.41e-01
GO:0008408 3’-5’ exonuclease activity	10	9.24e-01	1.74e-02	9.64e-01
GO:0051604 protein maturation	20	8.94e-01	1.73e-02	9.57e-01
GO:0019899 enzyme binding	112	7.54e-01	1.72e-02	8.74e-01
GO:0007346 regulation of mitotic cell cycle	31	8.69e-01	-1.71e-02	9.44e-01
GO:0045184 establishment of protein localization	17	9.04e-01	1.69e-02	9.59e-01
GO:0055037 recycling endosome	56	8.27e-01	-1.69e-02	9.16e-01
GO:0006511 ubiquitin-dependent protein catabolic process	117	7.54e-01	1.68e-02	8.74e-01
GO:0043539 protein serine/threonine kinase activator activity	34	8.67e-01	1.66e-02	9.42e-01
GO:0003774 cytoskeletal motor activity	12	9.21e-01	-1.66e-02	9.64e-01
GO:0045739 positive regulation of DNA repair	20	9.01e-01	-1.61e-02	9.59e-01
GO:0030665 clathrin-coated vesicle membrane	11	9.27e-01	-1.61e-02	9.64e-01
GO:0051020 GTPase binding	15	9.15e-01	1.58e-02	9.64e-01
GO:0009611 response to wounding	19	9.07e-01	-1.56e-02	9.60e-01
GO:0007528 neuromuscular junction development	15	9.17e-01	1.55e-02	9.64e-01
GO:0002224 toll-like receptor signaling pathway	15	9.17e-01	1.55e-02	9.64e-01
GO:0051082 unfolded protein binding	56	8.42e-01	-1.55e-02	9.22e-01
GO:0071007 U2-type catalytic step 2 spliceosome	24	8.96e-01	1.54e-02	9.57e-01
GO:0005004 GPI-linked ephrin receptor activity	12	9.26e-01	-1.54e-02	9.64e-01
GO:0005011 macrophage colony-stimulating factor receptor activity	12	9.26e-01	-1.54e-02	9.64e-01
GO:0005018 platelet-derived growth factor alpha-receptor activity	12	9.26e-01	-1.54e-02	9.64e-01
GO:0005020 stem cell factor receptor activity	12	9.26e-01	-1.54e-02	9.64e-01
GO:0008288 boss receptor activity	12	9.26e-01	-1.54e-02	9.64e-01
GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway	12	9.26e-01	-1.54e-02	9.64e-01
GO:0036323 vascular endothelial growth factor receptor-1 signaling pathway	12	9.26e-01	-1.54e-02	9.64e-01
GO:0036332 placental growth factor receptor activity	12	9.26e-01	-1.54e-02	9.64e-01
GO:0038145 macrophage colony-stimulating factor signaling pathway	12	9.26e-01	-1.54e-02	9.64e-01
GO:0060175 brain-derived neurotrophic factor receptor activity	12	9.26e-01	-1.54e-02	9.64e-01
GO:0042102 positive regulation of T cell proliferation	10	9.33e-01	1.53e-02	9.67e-01
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway	11	9.31e-01	1.51e-02	9.67e-01
GO:0000145 exocyst	11	9.31e-01	-1.51e-02	9.67e-01
GO:0006289 nucleotide-excision repair	22	9.03e-01	1.51e-02	9.59e-01
GO:0060090 molecular adaptor activity	75	8.22e-01	1.50e-02	9.15e-01
GO:0060325 face morphogenesis	20	9.09e-01	-1.48e-02	9.60e-01
GO:0017134 fibroblast growth factor binding	12	9.31e-01	-1.44e-02	9.67e-01
GO:0000993 RNA polymerase II complex binding	23	9.08e-01	-1.39e-02	9.60e-01
GO:0017025 TBP-class protein binding	18	9.21e-01	1.36e-02	9.64e-01
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity	16	9.25e-01	1.36e-02	9.64e-01
GO:0046330 positive regulation of JNK cascade	38	8.85e-01	-1.35e-02	9.50e-01
GO:0034067 protein localization to Golgi apparatus	12	9.37e-01	-1.32e-02	9.68e-01
GO:0060586 multicellular organismal-level iron ion homeostasis	16	9.29e-01	-1.29e-02	9.66e-01
GO:0001938 positive regulation of endothelial cell proliferation	23	9.16e-01	-1.27e-02	9.64e-01
GO:0007204 positive regulation of cytosolic calcium ion concentration	20	9.25e-01	-1.22e-02	9.64e-01
GO:0001540 amyloid-beta binding	28	9.12e-01	1.21e-02	9.62e-01
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding	40	8.96e-01	1.19e-02	9.57e-01
GO:0016197 endosomal transport	27	9.18e-01	-1.15e-02	9.64e-01
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding	13	9.43e-01	-1.14e-02	9.73e-01
GO:0030136 clathrin-coated vesicle	29	9.16e-01	-1.13e-02	9.64e-01
GO:0001782 B cell homeostasis	12	9.46e-01	1.13e-02	9.73e-01
GO:0043410 positive regulation of MAPK cascade	62	8.78e-01	1.13e-02	9.47e-01
GO:0000209 protein polyubiquitination	77	8.65e-01	-1.13e-02	9.41e-01
GO:0042383 sarcolemma	36	9.07e-01	-1.12e-02	9.60e-01
GO:0043066 negative regulation of apoptotic process	151	8.13e-01	1.12e-02	9.08e-01
GO:0005768 endosome	113	8.38e-01	-1.11e-02	9.22e-01
GO:0030307 positive regulation of cell growth	36	9.09e-01	1.11e-02	9.60e-01
GO:0034113 heterotypic cell-cell adhesion	12	9.47e-01	-1.10e-02	9.73e-01
GO:0036464 cytoplasmic ribonucleoprotein granule	36	9.09e-01	1.10e-02	9.60e-01
GO:1990573 potassium ion import across plasma membrane	18	9.36e-01	-1.10e-02	9.68e-01
GO:0002020 protease binding	43	9.02e-01	1.08e-02	9.59e-01
GO:0008277 regulation of G protein-coupled receptor signaling pathway	16	9.41e-01	-1.07e-02	9.72e-01
GO:0070971 endoplasmic reticulum exit site	19	9.36e-01	1.06e-02	9.68e-01
GO:0002062 chondrocyte differentiation	22	9.32e-01	-1.05e-02	9.67e-01
GO:0016459 myosin complex	22	9.34e-01	1.02e-02	9.67e-01
GO:0032743 positive regulation of interleukin-2 production	16	9.44e-01	1.02e-02	9.73e-01
GO:0036126 sperm flagellum	32	9.21e-01	1.01e-02	9.64e-01
GO:0030030 cell projection organization	13	9.51e-01	-9.88e-03	9.75e-01
GO:0070374 positive regulation of ERK1 and ERK2 cascade	58	8.97e-01	-9.82e-03	9.58e-01
GO:0070273 phosphatidylinositol-4-phosphate binding	17	9.45e-01	9.73e-03	9.73e-01
GO:0009898 cytoplasmic side of plasma membrane	47	9.09e-01	-9.67e-03	9.60e-01
GO:0071277 cellular response to calcium ion	32	9.25e-01	9.60e-03	9.64e-01
GO:0006884 cell volume homeostasis	14	9.51e-01	9.49e-03	9.75e-01
GO:0005102 signaling receptor binding	81	8.83e-01	9.43e-03	9.50e-01
GO:0071480 cellular response to gamma radiation	14	9.55e-01	8.80e-03	9.77e-01
GO:0090316 positive regulation of intracellular protein transport	14	9.55e-01	-8.78e-03	9.77e-01
GO:0051321 meiotic cell cycle	21	9.46e-01	-8.60e-03	9.73e-01
GO:0030041 actin filament polymerization	15	9.55e-01	-8.49e-03	9.77e-01
GO:0046835 carbohydrate phosphorylation	20	9.48e-01	-8.38e-03	9.74e-01
GO:0005776 autophagosome	41	9.33e-01	7.59e-03	9.67e-01
GO:0005681 spliceosomal complex	43	9.34e-01	7.25e-03	9.67e-01
GO:0030837 negative regulation of actin filament polymerization	14	9.63e-01	7.09e-03	9.83e-01
GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity	13	9.65e-01	7.04e-03	9.83e-01
GO:0005005 transmembrane-ephrin receptor activity	14	9.64e-01	6.99e-03	9.83e-01
GO:0006094 gluconeogenesis	21	9.56e-01	6.95e-03	9.77e-01
GO:0032956 regulation of actin cytoskeleton organization	37	9.46e-01	-6.38e-03	9.73e-01
GO:0005249 voltage-gated potassium channel activity	13	9.69e-01	6.14e-03	9.86e-01
GO:0030687 preribosome, large subunit precursor	12	9.71e-01	6.05e-03	9.86e-01
GO:0016592 mediator complex	28	9.56e-01	-6.00e-03	9.77e-01
GO:0048666 neuron development	26	9.59e-01	5.86e-03	9.79e-01
GO:0009410 response to xenobiotic stimulus	46	9.47e-01	5.65e-03	9.73e-01
GO:0099149 regulation of postsynaptic neurotransmitter receptor internalization	12	9.73e-01	5.65e-03	9.87e-01
GO:0045087 innate immune response	79	9.33e-01	5.46e-03	9.67e-01
GO:0034198 cellular response to amino acid starvation	31	9.58e-01	5.45e-03	9.79e-01
GO:0009953 dorsal/ventral pattern formation	16	9.70e-01	5.42e-03	9.86e-01
GO:0048146 positive regulation of fibroblast proliferation	19	9.68e-01	-5.38e-03	9.85e-01
GO:0007099 centriole replication	13	9.74e-01	5.30e-03	9.87e-01
GO:0030145 manganese ion binding	45	9.55e-01	-4.91e-03	9.77e-01
GO:0071011 precatalytic spliceosome	12	9.77e-01	4.90e-03	9.89e-01
GO:0006303 double-strand break repair via nonhomologous end joining	20	9.71e-01	-4.70e-03	9.86e-01
GO:0140326 ATPase-coupled intramembrane lipid transporter activity	11	9.79e-01	4.60e-03	9.90e-01
GO:0097060 synaptic membrane	11	9.79e-01	-4.56e-03	9.90e-01
GO:0070534 protein K63-linked ubiquitination	31	9.70e-01	3.86e-03	9.86e-01
GO:0048013 ephrin receptor signaling pathway	24	9.78e-01	3.18e-03	9.90e-01
GO:0031369 translation initiation factor binding	12	9.85e-01	-3.17e-03	9.95e-01
GO:0070628 proteasome binding	13	9.84e-01	-3.16e-03	9.95e-01
GO:0030522 intracellular receptor signaling pathway	18	9.86e-01	2.40e-03	9.96e-01
GO:0045022 early endosome to late endosome transport	19	9.88e-01	-2.06e-03	9.97e-01
GO:0050796 regulation of insulin secretion	12	9.91e-01	-1.84e-03	9.99e-01
GO:0000176 nuclear exosome (RNase complex)	12	9.91e-01	1.79e-03	9.99e-01
GO:0070098 chemokine-mediated signaling pathway	11	9.93e-01	-1.61e-03	9.99e-01
GO:0005509 calcium ion binding	256	9.66e-01	1.55e-03	9.84e-01
GO:0030178 negative regulation of Wnt signaling pathway	17	9.92e-01	1.43e-03	9.99e-01
GO:0032715 negative regulation of interleukin-6 production	14	9.93e-01	1.43e-03	9.99e-01
GO:0061136 regulation of proteasomal protein catabolic process	11	9.94e-01	1.31e-03	9.99e-01
GO:0004683 calcium/calmodulin-dependent protein kinase activity	11	9.95e-01	-1.12e-03	9.99e-01
GO:0005666 RNA polymerase III complex	12	9.96e-01	-8.33e-04	9.99e-01
GO:0004622 lysophospholipase activity	10	9.97e-01	6.47e-04	9.99e-01
GO:0005543 phospholipid binding	38	9.95e-01	5.82e-04	9.99e-01
GO:0101031 protein folding chaperone complex	18	9.97e-01	5.47e-04	9.99e-01
GO:0035869 ciliary transition zone	22	9.97e-01	5.25e-04	9.99e-01
GO:0006816 calcium ion transport	19	9.98e-01	3.00e-04	1.00e+00
GO:0000266 mitochondrial fission	10	9.99e-01	1.41e-04	1.00e+00
GO:0071353 cellular response to interleukin-4	10	1.00e+00	1.13e-04	1.00e+00
GO:0030658 transport vesicle membrane	13	1.00e+00	5.41e-06	1.00e+00

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Detailed Gene set reports

GO:0022625 cytosolic large ribosomal subunit

set	GO:0022625 cytosolic large ribosomal subunit
setSize	40
pANOVA	1.11e-22
s.dist	-0.895
p.adjustANOVA	6.53e-20

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL5	-7005
RPL7A	-6987
RPL27A	-6980
RPL26L1	-6971
RPL29	-6965
RPL9	-6950
RPL15	-6937
RPL31	-6927
RPL3	-6914
RPL37	-6911
RPL38	-6903
RPL8	-6877
RPL7	-6874
RPL35A	-6871
RPL34	-6870
RPL11	-6867
RPL13	-6839
RPL35	-6835
RPL18A	-6827
RPL37A	-6824

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL5	-7005
RPL7A	-6987
RPL27A	-6980
RPL26L1	-6971
RPL29	-6965
RPL9	-6950
RPL15	-6937
RPL31	-6927
RPL3	-6914
RPL37	-6911
RPL38	-6903
RPL8	-6877
RPL7	-6874
RPL35A	-6871
RPL34	-6870
RPL11	-6867
RPL13	-6839
RPL35	-6835
RPL18A	-6827
RPL37A	-6824
RPL32	-6822
RPL23A	-6820
RPL30	-6788
RPL24	-6751
RPL14	-6732
RPL10A	-6696
RPL21	-6657
RPL27	-6591
RPL36	-6504
RPL23	-6463
RPL4	-6416
RPL7L1	-6414
RPLP2	-6315
RPL12	-6299
RPL19	-5933
RPLP0	-5880
RPL6	-4002
ZCCHC17	-3197
RPLP1	-2459
RPL3L	1654

---

GO:0002181 cytoplasmic translation

set	GO:0002181 cytoplasmic translation
setSize	27
pANOVA	4.68e-14
s.dist	-0.838
p.adjustANOVA	6.32e-12

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL26L1	-6971
RPL29	-6965
RPS23	-6957
RPL9	-6950
RPL15	-6937
RPL31	-6927
RPL38	-6903
RPL8	-6877
RPS14	-6875
RPL35A	-6871
RPL18A	-6827
RPL24	-6751
RPL10A	-6696
RPS6	-6520
RPL36	-6504
RPL22L1	-6023
RPS28	-5900
RPLP0	-5880
RPS29	-5578
RPL22	-5502

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL26L1	-6971
RPL29	-6965
RPS23	-6957
RPL9	-6950
RPL15	-6937
RPL31	-6927
RPL38	-6903
RPL8	-6877
RPS14	-6875
RPL35A	-6871
RPL18A	-6827
RPL24	-6751
RPL10A	-6696
RPS6	-6520
RPL36	-6504
RPL22L1	-6023
RPS28	-5900
RPLP0	-5880
RPS29	-5578
RPL22	-5502
RWDD1	-5457
DRG2	-5317
RPS26	-4687
RPL6	-4002
SARS1	-3473
RPLP1	-2459
ZC3H15	-1385

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GO:0045116 protein neddylation

set	GO:0045116 protein neddylation
setSize	10
pANOVA	1.25e-05
s.dist	-0.798
p.adjustANOVA	0.000422

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UBE2F	-6859
RBX1	-6613
DCUN1D4	-6516
DCUN1D5	-6476
UBA3	-6451
RNF7	-5425
DCUN1D2	-5417
NEDD8	-4172
DCUN1D3	-3989
NAE1	-3892

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All member genes

GeneID	Gene Rank
UBE2F	-6859
RBX1	-6613
DCUN1D4	-6516
DCUN1D5	-6476
UBA3	-6451
RNF7	-5425
DCUN1D2	-5417
NEDD8	-4172
DCUN1D3	-3989
NAE1	-3892

---

GO:0022627 cytosolic small ribosomal subunit

set	GO:0022627 cytosolic small ribosomal subunit
setSize	25
pANOVA	9.06e-12
s.dist	-0.788
p.adjustANOVA	8.85e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS24	-7002
RPS3	-7001
RPS3A	-6988
RPS7	-6975
RPS2	-6972
RPS12	-6966
RPS23	-6957
RPS16	-6945
RPS15A	-6941
RPS4Y1	-6939
RPS14	-6875
RPS20	-6765
RPS15	-6756
RPS8	-6729
RPS6	-6520
RPS11	-6342
RPS21	-6034
RPS28	-5900
RPS29	-5578
RPS26	-4687

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All member genes

GeneID	Gene Rank
RPS24	-7002
RPS3	-7001
RPS3A	-6988
RPS7	-6975
RPS2	-6972
RPS12	-6966
RPS23	-6957
RPS16	-6945
RPS15A	-6941
RPS4Y1	-6939
RPS14	-6875
RPS20	-6765
RPS15	-6756
RPS8	-6729
RPS6	-6520
RPS11	-6342
RPS21	-6034
RPS28	-5900
RPS29	-5578
RPS26	-4687
RPS27L	-4126
EIF2A	-3859
RPS10	-2825
RPS13	-1958
LARP4	7050

---

GO:0007076 mitotic chromosome condensation

set	GO:0007076 mitotic chromosome condensation
setSize	10
pANOVA	2.24e-05
s.dist	0.774
p.adjustANOVA	0.000656

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SMC2	7058
NCAPD2	7006
SMC4	6275
AKAP8L	6260
NCAPH	5921
NCAPG	5642
NCAPD3	5387
NCAPH2	4949
NUSAP1	4378
PHF13	3044

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SMC2	7058
NCAPD2	7006
SMC4	6275
AKAP8L	6260
NCAPH	5921
NCAPG	5642
NCAPD3	5387
NCAPH2	4949
NUSAP1	4378
PHF13	3044

---

GO:0036121 double-stranded DNA helicase activity

set	GO:0036121 double-stranded DNA helicase activity
setSize	11
pANOVA	2.37e-05
s.dist	0.736
p.adjustANOVA	0.000671

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UPF1	7043
CHD7	6793
TWNK	6732
BLM	6405
MCM9	6288
MCM3	6157
ERCC3	5815
MCM5	5668
CHD1	5242
IGHMBP2	4468
MCM8	-2085

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UPF1	7043
CHD7	6793
TWNK	6732
BLM	6405
MCM9	6288
MCM3	6157
ERCC3	5815
MCM5	5668
CHD1	5242
IGHMBP2	4468
MCM8	-2085

---

GO:0035145 exon-exon junction complex

set	GO:0035145 exon-exon junction complex
setSize	10
pANOVA	5.88e-05
s.dist	0.734
p.adjustANOVA	0.00131

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UPF1	7043
SRSF1	6975
CASC3	6578
THRAP3	6490
UPF2	6443
PNN	6127
SMG6	5505
TDRD3	5310
UPF3B	3930
UPF3A	-1358

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UPF1	7043
SRSF1	6975
CASC3	6578
THRAP3	6490
UPF2	6443
PNN	6127
SMG6	5505
TDRD3	5310
UPF3B	3930
UPF3A	-1358

---

GO:0003735 structural constituent of ribosome

set	GO:0003735 structural constituent of ribosome
setSize	118
pANOVA	8.25e-41
s.dist	-0.712
p.adjustANOVA	1.45e-37

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MRPS31	-7008
RPL5	-7005
RPS24	-7002
RPS3	-7001
RPS3A	-6988
RPL27A	-6980
RPS7	-6975
RPS2	-6972
RPL26L1	-6971
RPS12	-6966
RPL29	-6965
RPS23	-6957
RPL9	-6950
RPS16	-6945
RPS15A	-6941
RPS4Y1	-6939
RPL15	-6937
RPL31	-6927
RPL3	-6914
RPL37	-6911

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MRPS31	-7008
RPL5	-7005
RPS24	-7002
RPS3	-7001
RPS3A	-6988
RPL27A	-6980
RPS7	-6975
RPS2	-6972
RPL26L1	-6971
RPS12	-6966
RPL29	-6965
RPS23	-6957
RPL9	-6950
RPS16	-6945
RPS15A	-6941
RPS4Y1	-6939
RPL15	-6937
RPL31	-6927
RPL3	-6914
RPL37	-6911
RPL38	-6903
RPL8	-6877
RPS14	-6875
RPL7	-6874
RPL35A	-6871
RPL34	-6870
RPL11	-6867
RPL13	-6839
RPL35	-6835
RPL18A	-6827
RPL37A	-6824
RPL32	-6822
RPS17	-6821
RPL23A	-6820
RPL30	-6788
RPS20	-6765
RPS15	-6756
RPL24	-6751
RPS27A	-6749
RPL14	-6732
RPS8	-6729
RPL10A	-6696
RPL21	-6657
RPL27	-6591
RPS6	-6520
MRPS17	-6514
RPL36	-6504
RPL23	-6463
RPL4	-6416
RPL7L1	-6414
MRPL21	-6386
MRPL35	-6349
RPS11	-6342
RPLP2	-6315
RPL12	-6299
MRPS11	-6110
MRPL18	-6037
RPS21	-6034
RPL22L1	-6023
MRPS18C	-5987
MRPS23	-5945
RPL19	-5933
RPS28	-5900
RPLP0	-5880
MRPL27	-5872
MRPL13	-5848
MRPS21	-5784
MRPL51	-5746
MRPL37	-5603
MRPS34	-5583
RPS29	-5578
RPL22	-5502
MRPL23	-5395
SRBD1	-5239
MRPS35	-5101
MRPL32	-5075
MRPS9	-4916
MRPL2	-4870
MRPS25	-4760
MRPL47	-4726
RPS26	-4687
MRPS22	-4681
MRPL14	-4645
UBA52	-4475
MRPS16	-4449
MRPL16	-4439
MRPS10	-4373
DAP3	-4130
RPS27L	-4126
RPL6	-4002
MRPL19	-3979
MRPS18A	-3964
MRPL10	-3769
DDA1	-3761
MRPL22	-3732
MRPL41	-3604
MRPL28	-3477
MRPL46	-3169
MRPS6	-3125
RPS10	-2825
MRPS12	-2675
RPLP1	-2459
RPS13	-1958
MRPL36	-1880
MRPL15	-1252
MRPL3	-1145
MRPS7	-831
MRPL20	-781
MRPL24	133
MRPS15	482
RPL3L	1654
MRPS2	2194
MRPL17	2453
MRPS14	2477
MRPS30	2519
MRPL49	3250
MRPS5	3256
MRPL12	4446

---

GO:0021915 neural tube development

set	GO:0021915 neural tube development
setSize	15
pANOVA	3.23e-06
s.dist	0.694
p.adjustANOVA	0.000145

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PKD2	6899
NOTCH1	6815
AMBRA1	6390
C2CD3	6358
SEMA3C	6291
NUP133	6252
INTU	6197
PKD1	5133
PLXNA2	5043
DACT1	4576
DVL1	4435
EPHA2	3722
TGFB2	3418
GRHL2	3086
PROX1	718

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PKD2	6899
NOTCH1	6815
AMBRA1	6390
C2CD3	6358
SEMA3C	6291
NUP133	6252
INTU	6197
PKD1	5133
PLXNA2	5043
DACT1	4576
DVL1	4435
EPHA2	3722
TGFB2	3418
GRHL2	3086
PROX1	718

---

GO:1902774 late endosome to lysosome transport

set	GO:1902774 late endosome to lysosome transport
setSize	10
pANOVA	0.000144
s.dist	-0.694
p.adjustANOVA	0.00276

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CHMP2B	-6531
CHMP1B	-6484
VPS39	-6459
CHMP3	-6082
VPS41	-5882
CHMP5	-5172
CHMP2A	-4151
C9orf72	-4112
CHMP7	-3499
CHMP4C	-64

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CHMP2B	-6531
CHMP1B	-6484
VPS39	-6459
CHMP3	-6082
VPS41	-5882
CHMP5	-5172
CHMP2A	-4151
C9orf72	-4112
CHMP7	-3499
CHMP4C	-64

---

GO:0000228 nuclear chromosome

set	GO:0000228 nuclear chromosome
setSize	13
pANOVA	3.26e-05
s.dist	0.665
p.adjustANOVA	0.000818

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TOP1	7145
HNRNPU	7135
SMC2	7058
NCAPD2	7006
ATRX	6976
BAZ1A	6382
SETX	6149
IK	5088
SPO11	4599
PINX1	4402
SMARCB1	3127
FIGNL1	1504
EXOSC9	-3930

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TOP1	7145
HNRNPU	7135
SMC2	7058
NCAPD2	7006
ATRX	6976
BAZ1A	6382
SETX	6149
IK	5088
SPO11	4599
PINX1	4402
SMARCB1	3127
FIGNL1	1504
EXOSC9	-3930

---

GO:0070034 telomerase RNA binding

set	GO:0070034 telomerase RNA binding
setSize	12
pANOVA	8.35e-05
s.dist	0.656
p.adjustANOVA	0.00177

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HNRNPU	7135
SMG7	6858
SMG5	6794
GAR1	5623
SMG6	5505
DHX36	5345
EXOSC10	5191
PARN	4452
PINX1	4402
XRN1	4159
DKC1	1980
NAF1	-437

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HNRNPU	7135
SMG7	6858
SMG5	6794
GAR1	5623
SMG6	5505
DHX36	5345
EXOSC10	5191
PARN	4452
PINX1	4402
XRN1	4159
DKC1	1980
NAF1	-437

---

GO:0005049 nuclear export signal receptor activity

set	GO:0005049 nuclear export signal receptor activity
setSize	10
pANOVA	0.000375
s.dist	0.65
p.adjustANOVA	0.00549

Top enriched genes

Top 20 genes

GeneID	Gene Rank
XPO5	6937
XPO6	6784
NUP214	6731
XPO7	6640
CALR	5886
EIF4ENIF1	5753
XPO4	4194
CSE1L	2947
NUP42	1634
XPO1	-439

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
XPO5	6937
XPO6	6784
NUP214	6731
XPO7	6640
CALR	5886
EIF4ENIF1	5753
XPO4	4194
CSE1L	2947
NUP42	1634
XPO1	-439

---

GO:1990518 single-stranded 3’-5’ DNA helicase activity

set	GO:1990518 single-stranded 3’-5’ DNA helicase activity
setSize	11
pANOVA	0.000198
s.dist	0.648
p.adjustANOVA	0.00345

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CHD7	6793
TWNK	6732
BLM	6405
MCM9	6288
MCM3	6157
ERCC3	5815
MCM5	5668
MCM6	5593
CHD1	5242
HELQ	-963
MCM8	-2085

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CHD7	6793
TWNK	6732
BLM	6405
MCM9	6288
MCM3	6157
ERCC3	5815
MCM5	5668
MCM6	5593
CHD1	5242
HELQ	-963
MCM8	-2085

---

GO:0000793 condensed chromosome

set	GO:0000793 condensed chromosome
setSize	13
pANOVA	5.5e-05
s.dist	0.646
p.adjustANOVA	0.00126

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TOP2A	7184
BAZ1B	7099
SMC2	7058
NCAPD2	7006
RIF1	6979
CTCF	6548
HMGB2	6264
NCAPG	5642
CDK2	5054
FANCD2	4370
SMARCA5	3399
TOP3B	-103
LIG4	-5657

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TOP2A	7184
BAZ1B	7099
SMC2	7058
NCAPD2	7006
RIF1	6979
CTCF	6548
HMGB2	6264
NCAPG	5642
CDK2	5054
FANCD2	4370
SMARCA5	3399
TOP3B	-103
LIG4	-5657

---

GO:2000737 negative regulation of stem cell differentiation

set	GO:2000737 negative regulation of stem cell differentiation
setSize	12
pANOVA	0.000112
s.dist	0.644
p.adjustANOVA	0.00224

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HNRNPU	7135
CDK12	6942
NOTCH1	6815
CDK13	6629
YTHDF2	6058
TBX3	5777
YAP1	5493
STAT3	5397
EZH2	3631
HES1	3153
ZFP36L2	3049
JAG1	-4088

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HNRNPU	7135
CDK12	6942
NOTCH1	6815
CDK13	6629
YTHDF2	6058
TBX3	5777
YAP1	5493
STAT3	5397
EZH2	3631
HES1	3153
ZFP36L2	3049
JAG1	-4088

---

GO:0140658 ATP-dependent chromatin remodeler activity

set	GO:0140658 ATP-dependent chromatin remodeler activity
setSize	11
pANOVA	0.000232
s.dist	0.641
p.adjustANOVA	0.00392

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CHD4	7140
CHD6	7074
CHD2	7018
RAD54L2	6922
CHD7	6793
CHD5	5573
CHD1	5242
CHD1L	4632
INO80	4355
ERCC6	1344
SMARCAD1	-4996

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CHD4	7140
CHD6	7074
CHD2	7018
RAD54L2	6922
CHD7	6793
CHD5	5573
CHD1	5242
CHD1L	4632
INO80	4355
ERCC6	1344
SMARCAD1	-4996

---

GO:0061749 forked DNA-dependent helicase activity

set	GO:0061749 forked DNA-dependent helicase activity
setSize	10
pANOVA	0.000456
s.dist	0.64
p.adjustANOVA	0.00627

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CHD7	6793
TWNK	6732
BLM	6405
MCM9	6288
MCM3	6157
ERCC3	5815
MCM5	5668
CHD1	5242
WRN	-621
MCM8	-2085

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CHD7	6793
TWNK	6732
BLM	6405
MCM9	6288
MCM3	6157
ERCC3	5815
MCM5	5668
CHD1	5242
WRN	-621
MCM8	-2085

---

GO:1990023 mitotic spindle midzone

set	GO:1990023 mitotic spindle midzone
setSize	10
pANOVA	0.00069
s.dist	0.62
p.adjustANOVA	0.00854

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HNRNPU	7135
KIF20B	7085
PRC1	6984
KIF18B	6977
NUMA1	6565
KIF18A	5101
RCC2	4777
MAP10	4005
CTTN	3333
EML1	-7015

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HNRNPU	7135
KIF20B	7085
PRC1	6984
KIF18B	6977
NUMA1	6565
KIF18A	5101
RCC2	4777
MAP10	4005
CTTN	3333
EML1	-7015

---

GO:0017056 structural constituent of nuclear pore

set	GO:0017056 structural constituent of nuclear pore
setSize	19
pANOVA	5.23e-06
s.dist	0.604
p.adjustANOVA	0.000214

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TPR	7143
NUP98	7012
NUP205	6834
NUP214	6731
NUP160	6684
NUP188	6607
NUP153	6343
NUP155	6328
NUP133	6252
NUP62	6134
NUP58	5645
NUP107	4175
NDC1	4070
NUP35	3048
NUP85	2846
NUP93	2551
NUP88	2146
NUP54	-894
NUTF2	-6486

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TPR	7143
NUP98	7012
NUP205	6834
NUP214	6731
NUP160	6684
NUP188	6607
NUP153	6343
NUP155	6328
NUP133	6252
NUP62	6134
NUP58	5645
NUP107	4175
NDC1	4070
NUP35	3048
NUP85	2846
NUP93	2551
NUP88	2146
NUP54	-894
NUTF2	-6486

---

GO:0070064 proline-rich region binding

set	GO:0070064 proline-rich region binding
setSize	10
pANOVA	0.000951
s.dist	0.604
p.adjustANOVA	0.0106

Top enriched genes

Top 20 genes

GeneID	Gene Rank
WBP4	6151
TCERG1	6052
GIGYF2	5893
YAP1	5493
CCND1	5232
APBB1	5112
CYLD	4563
GAREM1	4482
ITSN1	4420
NEDD4	-3605

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
WBP4	6151
TCERG1	6052
GIGYF2	5893
YAP1	5493
CCND1	5232
APBB1	5112
CYLD	4563
GAREM1	4482
ITSN1	4420
NEDD4	-3605

---

GO:0006412 translation

set	GO:0006412 translation
setSize	96
pANOVA	3.49e-24
s.dist	-0.599
p.adjustANOVA	3.06e-21

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL5	-7005
RPS24	-7002
RPS3	-7001
RPS3A	-6988
RPL27A	-6980
RPS7	-6975
RPS2	-6972
RPL26L1	-6971
RPS23	-6957
RPS16	-6945
RPS15A	-6941
RPS4Y1	-6939
RPL3	-6914
RPL37	-6911
RPS14	-6875
RPL35A	-6871
RPL34	-6870
RPL11	-6867
RPL13	-6839
RPL35	-6835

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL5	-7005
RPS24	-7002
RPS3	-7001
RPS3A	-6988
RPL27A	-6980
RPS7	-6975
RPS2	-6972
RPL26L1	-6971
RPS23	-6957
RPS16	-6945
RPS15A	-6941
RPS4Y1	-6939
RPL3	-6914
RPL37	-6911
RPS14	-6875
RPL35A	-6871
RPL34	-6870
RPL11	-6867
RPL13	-6839
RPL35	-6835
RPL37A	-6824
RPL32	-6822
RPS17	-6821
RPL23A	-6820
RPS20	-6765
RPS15	-6756
RPS27A	-6749
RPL14	-6732
RPS8	-6729
RPL21	-6657
RPL27	-6591
MRPS17	-6514
RPL23	-6463
RPL4	-6416
MRPL35	-6349
RPS11	-6342
RPL12	-6299
MRPS11	-6110
MRPL18	-6037
RPS21	-6034
RPL22L1	-6023
MRPS18C	-5987
MRPS23	-5945
RPL19	-5933
MRPL27	-5872
MRPL13	-5848
MRPS21	-5784
MRPL51	-5746
C2H6orf52	-5744
MRPL37	-5603
RPS29	-5578
RPL22	-5502
SRBD1	-5239
MRPL32	-5075
MRPS9	-4916
MRPL2	-4870
MRPL47	-4726
MRPL14	-4645
EIF2AK2	-4506
UBA52	-4475
MRPS16	-4449
MRPL16	-4439
MRPS10	-4373
RPS27L	-4126
MRPL19	-3979
MRPS18A	-3964
MRPL10	-3769
DDA1	-3761
MRPL22	-3732
MRPL41	-3604
MRPS6	-3125
CPEB3	-2913
MRPS12	-2675
TRNAU1AP	-2471
RPS13	-1958
MRPL36	-1880
MRPL15	-1252
GUF1	-1214
MRPL3	-1145
MRPS7	-831
MRPL20	-781
MRPL24	133
HBS1L	442
MRPS15	482
MRPL33	1335
RPL3L	1654
MRPS2	2194
MRPL17	2453
MRPS14	2477
MRPS30	2519
MRPL49	3250
MRPS5	3256
MRPL12	4446
GSPT2	4792
CPEB4	5222
EIF4ENIF1	5753

---

GO:0004364 glutathione transferase activity

set	GO:0004364 glutathione transferase activity
setSize	10
pANOVA	0.00106
s.dist	-0.598
p.adjustANOVA	0.0117

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HPGDS	-6832
GSTO2	-6798
MGST1	-6761
MGST3	-6176
GSTZ1	-5541
GSTK1	-5511
GSTT1	-4434
GSTM2	-3666
LANCL1	-2439
PTGES	6556

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HPGDS	-6832
GSTO2	-6798
MGST1	-6761
MGST3	-6176
GSTZ1	-5541
GSTK1	-5511
GSTT1	-4434
GSTM2	-3666
LANCL1	-2439
PTGES	6556

---

GO:0006120 mitochondrial electron transport, NADH to ubiquinone

set	GO:0006120 mitochondrial electron transport, NADH to ubiquinone
setSize	19
pANOVA	6.85e-06
s.dist	-0.596
p.adjustANOVA	0.000256

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NDUFB9	-6773
NDUFAF1	-6616
ND5	-6502
NDUFV2	-6452
NDUFA8	-6263
NDUFA10	-6020
DLD	-5988
ND2	-5645
NDUFB6	-5458
NDUFS3	-5447
NDUFC2	-5028
DNAJC15	-4762
NDUFS8	-4723
NDUFB8	-3863
NDUFS1	-2962
NDUFS7	-2458
NDUFS6	-2057
NDUFS2	3051
NDUFV1	5217

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NDUFB9	-6773
NDUFAF1	-6616
ND5	-6502
NDUFV2	-6452
NDUFA8	-6263
NDUFA10	-6020
DLD	-5988
ND2	-5645
NDUFB6	-5458
NDUFS3	-5447
NDUFC2	-5028
DNAJC15	-4762
NDUFS8	-4723
NDUFB8	-3863
NDUFS1	-2962
NDUFS7	-2458
NDUFS6	-2057
NDUFS2	3051
NDUFV1	5217

---

GO:0071806 protein transmembrane transport

set	GO:0071806 protein transmembrane transport
setSize	12
pANOVA	0.000389
s.dist	-0.591
p.adjustANOVA	0.00565

Top enriched genes

Top 20 genes

GeneID	Gene Rank
EDNRA	-6840
IFT20	-6545
RAB11A	-6167
TMED10	-5895
TIMM22	-5638
EXOC4	-5139
SEC61G	-5115
BLOC1S6	-4775
DTNBP1	-4272
EXOC7	-3084
HPSE	-1414
TRIP11	5520

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
EDNRA	-6840
IFT20	-6545
RAB11A	-6167
TMED10	-5895
TIMM22	-5638
EXOC4	-5139
SEC61G	-5115
BLOC1S6	-4775
DTNBP1	-4272
EXOC7	-3084
HPSE	-1414
TRIP11	5520

---

GO:0000380 alternative mRNA splicing, via spliceosome

set	GO:0000380 alternative mRNA splicing, via spliceosome
setSize	16
pANOVA	4.58e-05
s.dist	0.589
p.adjustANOVA	0.00107

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HNRNPU	7135
SRSF1	6975
HNRNPM	6969
SFPQ	6918
HNRNPUL1	6680
CDK13	6629
DDX17	6411
SRSF6	6075
SLU7	5997
RBM17	4756
DDX5	4394
PUF60	3377
CELF2	855
SFSWAP	-453
STRAP	-1139
RSRC1	-3242

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HNRNPU	7135
SRSF1	6975
HNRNPM	6969
SFPQ	6918
HNRNPUL1	6680
CDK13	6629
DDX17	6411
SRSF6	6075
SLU7	5997
RBM17	4756
DDX5	4394
PUF60	3377
CELF2	855
SFSWAP	-453
STRAP	-1139
RSRC1	-3242

---

GO:0032585 multivesicular body membrane

set	GO:0032585 multivesicular body membrane
setSize	12
pANOVA	0.000495
s.dist	-0.581
p.adjustANOVA	0.0067

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RAB27A	-6612
CHMP2B	-6531
CHMP1B	-6484
CD63	-6289
CHMP3	-6082
CHMP5	-5172
SLC9A8	-4679
CHMP2A	-4151
CHMP7	-3499
TMEM9	-1987
CHMP4C	-64
SORL1	3097

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RAB27A	-6612
CHMP2B	-6531
CHMP1B	-6484
CD63	-6289
CHMP3	-6082
CHMP5	-5172
SLC9A8	-4679
CHMP2A	-4151
CHMP7	-3499
TMEM9	-1987
CHMP4C	-64
SORL1	3097

---

GO:0070577 lysine-acetylated histone binding

set	GO:0070577 lysine-acetylated histone binding
setSize	16
pANOVA	6.19e-05
s.dist	0.578
p.adjustANOVA	0.00136

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BRD2	7055
ZMYND8	6948
MLLT1	6859
DPF2	6659
KMT2A	6455
PHIP	6117
BRPF3	6046
BRD3	5936
TRIM24	5115
ZZEF1	4844
ATAD2B	4697
PSME4	4261
MLLT3	1949
ZZZ3	1219
BRD9	-2582
BRD7	-4401

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BRD2	7055
ZMYND8	6948
MLLT1	6859
DPF2	6659
KMT2A	6455
PHIP	6117
BRPF3	6046
BRD3	5936
TRIM24	5115
ZZEF1	4844
ATAD2B	4697
PSME4	4261
MLLT3	1949
ZZZ3	1219
BRD9	-2582
BRD7	-4401

---

GO:0006337 nucleosome disassembly

set	GO:0006337 nucleosome disassembly
setSize	10
pANOVA	0.0017
s.dist	0.573
p.adjustANOVA	0.0173

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SMARCC1	6901
SMARCA4	6835
SSRP1	6037
ATAD2	5560
SMARCD2	5237
ATAD2B	4697
ARID2	4071
SMARCB1	3127
SMARCD1	2682
SMARCE1	-3513

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SMARCC1	6901
SMARCA4	6835
SSRP1	6037
ATAD2	5560
SMARCD2	5237
ATAD2B	4697
ARID2	4071
SMARCB1	3127
SMARCD1	2682
SMARCE1	-3513

---

GO:0000245 spliceosomal complex assembly

set	GO:0000245 spliceosomal complex assembly
setSize	10
pANOVA	0.00177
s.dist	0.571
p.adjustANOVA	0.0177

Top enriched genes

Top 20 genes

GeneID	Gene Rank
USP39	6691
SCAF11	6403
SF3A2	6268
PRPF19	6126
ZRSR2	5571
SF3B1	5453
SRPK1	3847
RSRP1	2227
RBM10	1001
SRPK2	-2112

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
USP39	6691
SCAF11	6403
SF3A2	6268
PRPF19	6126
ZRSR2	5571
SF3B1	5453
SRPK1	3847
RSRP1	2227
RBM10	1001
SRPK2	-2112

---

GO:0003678 DNA helicase activity

set	GO:0003678 DNA helicase activity
setSize	20
pANOVA	1.11e-05
s.dist	0.568
p.adjustANOVA	0.00039

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SNRNP200	6947
DHX30	6735
TWNK	6732
G3BP1	6489
MCM9	6288
RAD50	6281
RTEL1	6023
XRCC6	5774
MCM4	5713
MCM6	5593
DHX36	5345
CHD1L	4632
DDX11	4500
MRE11	3854
RUVBL1	3218
DNA2	2845
BRIP1	2541
SUPV3L1	-583
RECQL5	-2082
XRCC5	-4416

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SNRNP200	6947
DHX30	6735
TWNK	6732
G3BP1	6489
MCM9	6288
RAD50	6281
RTEL1	6023
XRCC6	5774
MCM4	5713
MCM6	5593
DHX36	5345
CHD1L	4632
DDX11	4500
MRE11	3854
RUVBL1	3218
DNA2	2845
BRIP1	2541
SUPV3L1	-583
RECQL5	-2082
XRCC5	-4416

---

GO:0016581 NuRD complex

set	GO:0016581 NuRD complex
setSize	10
pANOVA	0.00203
s.dist	0.563
p.adjustANOVA	0.0193

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CHD4	7140
RBBP4	7002
GATAD2B	6722
MTA2	6682
GATAD2A	5584
CHD5	5573
MTA1	4843
RBBP7	3831
HDAC1	-712
HDAC2	-5722

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CHD4	7140
RBBP4	7002
GATAD2B	6722
MTA2	6682
GATAD2A	5584
CHD5	5573
MTA1	4843
RBBP7	3831
HDAC1	-712
HDAC2	-5722

---

GO:0035371 microtubule plus-end

set	GO:0035371 microtubule plus-end
setSize	12
pANOVA	0.000944
s.dist	0.551
p.adjustANOVA	0.0106

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KIF18B	6977
CKAP5	6938
NUMA1	6565
MAPRE2	6008
KIF2C	5994
CLIP2	5587
SLAIN2	5565
MAPRE3	3578
CLIP1	3289
DCTN1	2674
NCKAP5	-2239
KNSTRN	-2845

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KIF18B	6977
CKAP5	6938
NUMA1	6565
MAPRE2	6008
KIF2C	5994
CLIP2	5587
SLAIN2	5565
MAPRE3	3578
CLIP1	3289
DCTN1	2674
NCKAP5	-2239
KNSTRN	-2845

---

GO:0051010 microtubule plus-end binding

set	GO:0051010 microtubule plus-end binding
setSize	11
pANOVA	0.00158
s.dist	0.55
p.adjustANOVA	0.0164

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CKAP5	6938
NUMA1	6565
MAPRE2	6008
KIF2C	5994
CLIP2	5587
KIF18A	5101
MAPRE1	3828
MAPRE3	3578
CLIP1	3289
FBXW11	268
PAFAH1B1	-3151

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CKAP5	6938
NUMA1	6565
MAPRE2	6008
KIF2C	5994
CLIP2	5587
KIF18A	5101
MAPRE1	3828
MAPRE3	3578
CLIP1	3289
FBXW11	268
PAFAH1B1	-3151

---

GO:0007249 canonical NF-kappaB signal transduction

set	GO:0007249 canonical NF-kappaB signal transduction
setSize	18
pANOVA	5.43e-05
s.dist	0.55
p.adjustANOVA	0.00126

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ADAM8	7119
NFKB2	7025
REL	6983
CREBBP	6967
ABL1	6822
NFKB1	6767
EP300	6726
TRIM8	6651
TRADD	6593
CARD11	6259
MAP3K14	5057
NLRC3	4811
MAP3K7	4525
RIPK2	3361
IRAK2	-1212
TRAF6	-1525
RASSF2	-4392
IFT80	-6659

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ADAM8	7119
NFKB2	7025
REL	6983
CREBBP	6967
ABL1	6822
NFKB1	6767
EP300	6726
TRIM8	6651
TRADD	6593
CARD11	6259
MAP3K14	5057
NLRC3	4811
MAP3K7	4525
RIPK2	3361
IRAK2	-1212
TRAF6	-1525
RASSF2	-4392
IFT80	-6659

---

GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane

set	GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
setSize	18
pANOVA	5.75e-05
s.dist	-0.548
p.adjustANOVA	0.0013

Top enriched genes

Top 20 genes

GeneID	Gene Rank
VMA21	-6926
TMED2	-6809
RAB2A	-6031
TMED5	-5993
TMED10	-5895
ERGIC3	-5706
SEC22B	-5650
TMED7	-5384
TMEM199	-4395
PLPP3	-4077
ERGIC1	-3977
TMED3	-3767
ERGIC2	-3759
MPPE1	-3677
TMEM173	-2905
SURF4	-1186
WHAMM	1858
SPPL3	5857

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
VMA21	-6926
TMED2	-6809
RAB2A	-6031
TMED5	-5993
TMED10	-5895
ERGIC3	-5706
SEC22B	-5650
TMED7	-5384
TMEM199	-4395
PLPP3	-4077
ERGIC1	-3977
TMED3	-3767
ERGIC2	-3759
MPPE1	-3677
TMEM173	-2905
SURF4	-1186
WHAMM	1858
SPPL3	5857

---

GO:0051536 iron-sulfur cluster binding

set	GO:0051536 iron-sulfur cluster binding
setSize	12
pANOVA	0.0011
s.dist	-0.544
p.adjustANOVA	0.012

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PPAT	-6511
NUBP2	-6250
ISCA2	-6161
ISCA1	-6102
NUBP1	-5874
NFS1	-5824
GLRX3	-5533
ISCU	-5491
FBXL5	-5186
DPH1	-3396
REV3L	5409
DPH2	5577

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PPAT	-6511
NUBP2	-6250
ISCA2	-6161
ISCA1	-6102
NUBP1	-5874
NFS1	-5824
GLRX3	-5533
ISCU	-5491
FBXL5	-5186
DPH1	-3396
REV3L	5409
DPH2	5577

---

GO:1990391 DNA repair complex

set	GO:1990391 DNA repair complex
setSize	10
pANOVA	0.00319
s.dist	0.539
p.adjustANOVA	0.0259

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KDM1A	6671
TP53BP1	6512
FANCI	6463
BRCA2	5344
FANCD2	4370
BRCA1	3245
ATM	3017
PALB2	2838
ASCC2	1644
PHF21A	-932

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KDM1A	6671
TP53BP1	6512
FANCI	6463
BRCA2	5344
FANCD2	4370
BRCA1	3245
ATM	3017
PALB2	2838
ASCC2	1644
PHF21A	-932

---

GO:0008233 peptidase activity

set	GO:0008233 peptidase activity
setSize	10
pANOVA	0.0035
s.dist	-0.533
p.adjustANOVA	0.0277

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PARK7	-6698
LAP3	-5955
SEC11A	-5748
SEC11C	-5386
HMCES	-4651
CFAP44	-4479
NPEPL1	-3613
LMLN	-3292
PM20D1	-1607
LACTB	4414

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PARK7	-6698
LAP3	-5955
SEC11A	-5748
SEC11C	-5386
HMCES	-4651
CFAP44	-4479
NPEPL1	-3613
LMLN	-3292
PM20D1	-1607
LACTB	4414

---

GO:0006749 glutathione metabolic process

set	GO:0006749 glutathione metabolic process
setSize	15
pANOVA	0.000365
s.dist	-0.531
p.adjustANOVA	0.0054

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HPGDS	-6832
GSTO2	-6798
TXNRD3	-6492
SOD1	-6203
HAGH	-5705
GSTZ1	-5541
GSTK1	-5511
ARL6IP5	-5180
CTNS	-4929
GSTT1	-4434
GSTM2	-3666
GSR	-3239
GPX1	1485
MMACHC	1744
SLC7A11	5996

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HPGDS	-6832
GSTO2	-6798
TXNRD3	-6492
SOD1	-6203
HAGH	-5705
GSTZ1	-5541
GSTK1	-5511
ARL6IP5	-5180
CTNS	-4929
GSTT1	-4434
GSTM2	-3666
GSR	-3239
GPX1	1485
MMACHC	1744
SLC7A11	5996

---

GO:0045271 respiratory chain complex I

set	GO:0045271 respiratory chain complex I
setSize	31
pANOVA	3.33e-07
s.dist	-0.53
p.adjustANOVA	1.83e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NDUFB9	-6773
ND5	-6502
NDUFV2	-6452
NDUFS4	-6364
NDUFB3	-6352
NDUFA8	-6263
NDUFB5	-6202
NDUFA6	-6135
NDUFA10	-6020
NDUFA9	-6006
NDUFA5	-5783
NDUFA2	-5723
ND2	-5645
NDUFB6	-5458
NDUFS3	-5447
NDUFB2	-5288
NDUFC2	-5028
NDUFV3	-4919
NDUFS8	-4723
NDUFA12	-4446

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NDUFB9	-6773
ND5	-6502
NDUFV2	-6452
NDUFS4	-6364
NDUFB3	-6352
NDUFA8	-6263
NDUFB5	-6202
NDUFA6	-6135
NDUFA10	-6020
NDUFA9	-6006
NDUFA5	-5783
NDUFA2	-5723
ND2	-5645
NDUFB6	-5458
NDUFS3	-5447
NDUFB2	-5288
NDUFC2	-5028
NDUFV3	-4919
NDUFS8	-4723
NDUFA12	-4446
NDUFB8	-3863
NDUFS5	-3289
NDUFS1	-2962
NDUFS7	-2458
NDUFS6	-2057
NDUFA13	-109
NDUFB10	913
NDUFB4	2166
NDUFS2	3051
NDUFAB1	5162
NDUFV1	5217

---

GO:0005840 ribosome

set	GO:0005840 ribosome
setSize	43
pANOVA	2.98e-09
s.dist	-0.523
p.adjustANOVA	2.18e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SLC37A4	-7006
RPS23	-6957
RPS4Y1	-6939
RPL34	-6870
RPL11	-6867
RPL32	-6822
RPS17	-6821
RPL30	-6788
RPS27A	-6749
RPL27	-6591
MRPL35	-6349
MRPS33	-6274
MRPL18	-6037
RPS21	-6034
RPL22L1	-6023
MRPS18C	-5987
MRPS23	-5945
MRPL13	-5848
MRPS21	-5784
RPS29	-5578

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SLC37A4	-7006
RPS23	-6957
RPS4Y1	-6939
RPL34	-6870
RPL11	-6867
RPL32	-6822
RPS17	-6821
RPL30	-6788
RPS27A	-6749
RPL27	-6591
MRPL35	-6349
MRPS33	-6274
MRPL18	-6037
RPS21	-6034
RPL22L1	-6023
MRPS18C	-5987
MRPS23	-5945
MRPL13	-5848
MRPS21	-5784
RPS29	-5578
RPL22	-5502
FXR1	-5472
RACK1	-4917
MRPS9	-4916
PSMA6	-4867
MRPS25	-4760
UBA52	-4475
DDA1	-3761
MRPL46	-3169
MRPS6	-3125
MRPS12	-2675
RPLP1	-2459
MRPL1	-2424
PTCD3	-2226
MRPS7	-831
MRPL24	133
MRPL33	1335
MRPL45	1337
HSPA14	2760
GADD45GIP1	3438
EEF2	5517
NUFIP2	6563
EIF4G1	7170

---

GO:0051315 attachment of mitotic spindle microtubules to kinetochore

set	GO:0051315 attachment of mitotic spindle microtubules to kinetochore
setSize	10
pANOVA	0.00449
s.dist	0.519
p.adjustANOVA	0.0323

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CENPC	6745
CHAMP1	6302
MAD1L1	6039
KIF2C	5994
NDC80	5561
SKA3	4405
MAPRE1	3828
MIS12	3690
NUF2	184
SEH1L	-4966

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CENPC	6745
CHAMP1	6302
MAD1L1	6039
KIF2C	5994
NDC80	5561
SKA3	4405
MAPRE1	3828
MIS12	3690
NUF2	184
SEH1L	-4966

---

GO:0016442 RISC complex

set	GO:0016442 RISC complex
setSize	11
pANOVA	0.00291
s.dist	0.518
p.adjustANOVA	0.0245

Top enriched genes

Top 20 genes

GeneID	Gene Rank
DDX6	6996
XPO5	6937
TNRC6A	6581
LIMD1	6175
AGO3	5576
AGO4	4839
DICER1	4197
AGO2	4138
TARBP2	1788
DCP2	668
EIF4E	-6385

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
DDX6	6996
XPO5	6937
TNRC6A	6581
LIMD1	6175
AGO3	5576
AGO4	4839
DICER1	4197
AGO2	4138
TARBP2	1788
DCP2	668
EIF4E	-6385

---

GO:0035855 megakaryocyte development

set	GO:0035855 megakaryocyte development
setSize	10
pANOVA	0.00465
s.dist	0.517
p.adjustANOVA	0.0331

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MED1	7114
WASF2	6851
SRF	5607
SH2B3	5467
ZFPM1	4834
PIP4K2A	3591
ZNF385A	3582
FLI1	2704
MEIS1	2026
VPS33B	-4143

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MED1	7114
WASF2	6851
SRF	5607
SH2B3	5467
ZFPM1	4834
PIP4K2A	3591
ZNF385A	3582
FLI1	2704
MEIS1	2026
VPS33B	-4143

---

GO:0003151 outflow tract morphogenesis

set	GO:0003151 outflow tract morphogenesis
setSize	19
pANOVA	0.000104
s.dist	0.514
p.adjustANOVA	0.00213

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RBPJ	7054
NOTCH1	6815
FZD1	6730
SEC24B	6482
CTNNB1	6461
FZD2	6303
TBX3	5777
SOX11	5758
HEY2	5484
WNT11	5464
PLXND1	5447
ZFPM1	4834
DHRS3	4798
DVL1	4435
NPY2R	2593
ILK	370
ELN	-3196
HIF1A	-4541
PRICKLE1	-5957

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RBPJ	7054
NOTCH1	6815
FZD1	6730
SEC24B	6482
CTNNB1	6461
FZD2	6303
TBX3	5777
SOX11	5758
HEY2	5484
WNT11	5464
PLXND1	5447
ZFPM1	4834
DHRS3	4798
DVL1	4435
NPY2R	2593
ILK	370
ELN	-3196
HIF1A	-4541
PRICKLE1	-5957

---

GO:0032968 positive regulation of transcription elongation by RNA polymerase II

set	GO:0032968 positive regulation of transcription elongation by RNA polymerase II
setSize	15
pANOVA	0.000589
s.dist	0.513
p.adjustANOVA	0.00747

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ZMYND8	6948
CDK12	6942
ELL	6861
LEO1	6805
SUPT6H	6714
CDK13	6629
CTNNB1	6461
PWWP2B	5946
CCNT1	3662
PWWP2A	2626
CDC73	2160
OCLN	946
ELL2	253
CDK9	-1070
EAPP	-5913

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ZMYND8	6948
CDK12	6942
ELL	6861
LEO1	6805
SUPT6H	6714
CDK13	6629
CTNNB1	6461
PWWP2B	5946
CCNT1	3662
PWWP2A	2626
CDC73	2160
OCLN	946
ELL2	253
CDK9	-1070
EAPP	-5913

---

GO:0043296 apical junction complex

set	GO:0043296 apical junction complex
setSize	10
pANOVA	0.00521
s.dist	0.51
p.adjustANOVA	0.0355

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PKN2	6736
FRMD6	6597
SAPCD2	6147
PARD3B	5228
CCDC85C	5189
SHROOM2	4695
FBF1	4269
PARD3	2281
SHROOM3	-789
NECTIN3	-3194

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PKN2	6736
FRMD6	6597
SAPCD2	6147
PARD3B	5228
CCDC85C	5189
SHROOM2	4695
FBF1	4269
PARD3	2281
SHROOM3	-789
NECTIN3	-3194

---

GO:0031468 nuclear membrane reassembly

set	GO:0031468 nuclear membrane reassembly
setSize	11
pANOVA	0.00358
s.dist	-0.507
p.adjustANOVA	0.0282

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CHMP2B	-6531
CHMP3	-6082
CHMP5	-5172
UBXN2A	-4829
CHMP2A	-4151
CHMP7	-3499
SPAST	-3018
UBXN2B	-2829
NSFL1C	-2054
CHMP4B	-450
CHMP4C	-64

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CHMP2B	-6531
CHMP3	-6082
CHMP5	-5172
UBXN2A	-4829
CHMP2A	-4151
CHMP7	-3499
SPAST	-3018
UBXN2B	-2829
NSFL1C	-2054
CHMP4B	-450
CHMP4C	-64

---

GO:0031466 Cul5-RING ubiquitin ligase complex

set	GO:0031466 Cul5-RING ubiquitin ligase complex
setSize	11
pANOVA	0.00381
s.dist	-0.504
p.adjustANOVA	0.0294

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RBX1	-6613
TCEB1	-6567
KLHDC1	-5632
RNF7	-5425
ELOB	-5245
PCMTD1	-4951
CUL5	-4050
ASB9	-2556
ARIH2	-1228
SOCS2	53
SPSB3	3808

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RBX1	-6613
TCEB1	-6567
KLHDC1	-5632
RNF7	-5425
ELOB	-5245
PCMTD1	-4951
CUL5	-4050
ASB9	-2556
ARIH2	-1228
SOCS2	53
SPSB3	3808

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.4.2 (2024-10-31)
## Platform: x86_64-pc-linux-gnu
## Running under: Ubuntu 24.04.1 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.12.0 
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.12.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Australia/Melbourne
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] stats4    stats     graphics  grDevices utils     datasets  methods  
## [8] base     
## 
## other attached packages:
##  [1] pkgload_1.4.0               GGally_2.2.1               
##  [3] ggplot2_3.5.1               gtools_3.9.5               
##  [5] tibble_3.2.1                echarts4r_0.4.5            
##  [7] UpSetR_1.4.0                beeswarm_0.4.0             
##  [9] kableExtra_1.4.0            eulerr_7.0.2               
## [11] mitch_1.19.2                MASS_7.3-61                
## [13] gplots_3.2.0                DESeq2_1.44.0              
## [15] SummarizedExperiment_1.34.0 Biobase_2.64.0             
## [17] MatrixGenerics_1.16.0       matrixStats_1.4.1          
## [19] GenomicRanges_1.56.1        GenomeInfoDb_1.40.1        
## [21] IRanges_2.38.1              S4Vectors_0.42.1           
## [23] BiocGenerics_0.50.0         reshape2_1.4.4             
## [25] dplyr_1.1.4                 zoo_1.8-12                 
## 
## loaded via a namespace (and not attached):
##  [1] tidyselect_1.2.1        viridisLite_0.4.2       farver_2.1.2           
##  [4] bitops_1.0-9            fastmap_1.2.0           promises_1.3.2         
##  [7] digest_0.6.37           mime_0.12               lifecycle_1.0.4        
## [10] polylabelr_0.3.0        magrittr_2.0.3          compiler_4.4.2         
## [13] rlang_1.1.4             sass_0.4.9              tools_4.4.2            
## [16] yaml_2.3.10             knitr_1.49              labeling_0.4.3         
## [19] S4Arrays_1.4.1          htmlwidgets_1.6.4       DelayedArray_0.30.1    
## [22] xml2_1.3.6              plyr_1.8.9              RColorBrewer_1.1-3     
## [25] abind_1.4-8             BiocParallel_1.38.0     KernSmooth_2.23-24     
## [28] withr_3.0.2             purrr_1.0.2             polyclip_1.10-7        
## [31] grid_4.4.2              caTools_1.18.3          xtable_1.8-4           
## [34] colorspace_2.1-1        scales_1.3.0            cli_3.6.3              
## [37] rmarkdown_2.29          crayon_1.5.3            generics_0.1.3         
## [40] rstudioapi_0.17.1       httr_1.4.7              cachem_1.1.0           
## [43] stringr_1.5.1           zlibbioc_1.50.0         parallel_4.4.2         
## [46] XVector_0.44.0          vctrs_0.6.5             Matrix_1.7-1           
## [49] jsonlite_1.8.9          systemfonts_1.1.0       locfit_1.5-9.10        
## [52] jquerylib_0.1.4         tidyr_1.3.1             glue_1.8.0             
## [55] ggstats_0.7.0           codetools_0.2-20        stringi_1.8.4          
## [58] gtable_0.3.6            later_1.4.1             UCSC.utils_1.0.0       
## [61] munsell_0.5.1           pillar_1.10.0           htmltools_0.5.8.1      
## [64] GenomeInfoDbData_1.2.12 R6_2.5.1                evaluate_1.0.1         
## [67] shiny_1.10.0            lattice_0.22-6          httpuv_1.6.15          
## [70] bslib_0.8.0             Rcpp_1.0.13-1           svglite_2.1.3          
## [73] gridExtra_2.3           SparseArray_1.4.8       xfun_0.49              
## [76] pkgconfig_2.0.3

END of report