Mitch Report

date generated: 2025-01-14

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch

	stat
5_8S_rRNA	0.4129697
A4GALT	0.1866835
AAAS	1.4925591
AACS	0.6385135
AADAC	-0.5166120
AADAT	0.6338228

Here are some metrics about the input data profile:

Profiling data metrics

	Profile metrics
num_genesets	5133
num_genes_in_profile	14501
duplicated_genes_present	0
num_profile_genes_in_sets	9206
num_profile_genes_not_in_sets	5295

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets:

Gene set metrics

	Gene sets metrics
num_genesets	5133
num_genesets_excluded	3362
num_genesets_included	1771

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

set	setSize	pANOVA	s.dist	p.adjustANOVA
GO:0000245 spliceosomal complex assembly	10	6.52e-05	-0.729	8.62e-03
GO:0022625 cytosolic large ribosomal subunit	40	1.17e-12	0.649	1.93e-09
GO:0035145 exon-exon junction complex	10	4.12e-04	-0.645	3.32e-02
GO:0022627 cytosolic small ribosomal subunit	25	4.96e-07	0.581	2.93e-04
GO:0030127 COPII vesicle coat	10	2.01e-03	0.564	8.90e-02
GO:1905564 positive regulation of vascular endothelial cell proliferation	10	2.18e-03	0.560	8.99e-02
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway	11	1.61e-03	0.549	7.93e-02
GO:1903076 regulation of protein localization to plasma membrane	18	6.63e-05	0.543	8.62e-03
GO:0002181 cytoplasmic translation	27	1.69e-06	0.532	6.31e-04
GO:1903077 negative regulation of protein localization to plasma membrane	13	1.02e-03	0.526	6.22e-02
GO:0004364 glutathione transferase activity	10	5.73e-03	0.505	1.41e-01
GO:0004602 glutathione peroxidase activity	12	2.53e-03	0.503	9.74e-02
GO:0071353 cellular response to interleukin-4	10	5.92e-03	0.503	1.41e-01
GO:0004683 calcium/calmodulin-dependent protein kinase activity	11	5.60e-03	0.482	1.41e-01
GO:0044322 endoplasmic reticulum quality control compartment	11	5.84e-03	0.480	1.41e-01
GO:0051642 centrosome localization	14	1.91e-03	0.479	8.65e-02
GO:0007017 microtubule-based process	11	5.97e-03	0.479	1.41e-01
GO:0030020 extracellular matrix structural constituent conferring tensile strength	16	1.00e-03	0.475	6.22e-02
GO:0030100 regulation of endocytosis	12	4.77e-03	0.471	1.32e-01
GO:0008593 regulation of Notch signaling pathway	10	1.17e-02	0.460	1.79e-01
GO:0140662 ATP-dependent protein folding chaperone	23	1.49e-04	-0.457	1.63e-02
GO:0035925 mRNA 3’-UTR AU-rich region binding	13	4.61e-03	0.454	1.32e-01
GO:0090110 COPII-coated vesicle cargo loading	10	1.33e-02	0.452	1.93e-01
GO:0005791 rough endoplasmic reticulum	12	7.86e-03	-0.443	1.63e-01
GO:0044458 motile cilium assembly	12	7.93e-03	0.443	1.63e-01
GO:1902774 late endosome to lysosome transport	10	1.56e-02	0.442	2.06e-01
GO:0030863 cortical cytoskeleton	10	1.71e-02	0.435	2.21e-01
GO:0030992 intraciliary transport particle B	15	3.92e-03	0.430	1.25e-01
GO:0043995 histone H4K5 acetyltransferase activity	10	1.98e-02	-0.425	2.30e-01
GO:0043996 histone H4K8 acetyltransferase activity	10	1.98e-02	-0.425	2.30e-01
GO:0001772 immunological synapse	22	5.90e-04	0.423	4.02e-02
GO:0043997 histone H4K12 acetyltransferase activity	10	2.07e-02	-0.422	2.32e-01
GO:0061952 midbody abscission	14	7.55e-03	0.412	1.63e-01
GO:0048018 receptor ligand activity	18	2.46e-03	-0.412	9.66e-02
GO:0003724 RNA helicase activity	37	1.49e-05	-0.411	3.30e-03
GO:0070182 DNA polymerase binding	13	1.03e-02	-0.411	1.79e-01
GO:0060395 SMAD protein signal transduction	14	8.29e-03	-0.408	1.69e-01
GO:0040029 epigenetic regulation of gene expression	18	2.79e-03	-0.407	1.03e-01
GO:0032968 positive regulation of transcription elongation by RNA polymerase II	15	6.45e-03	-0.406	1.50e-01
GO:0005852 eukaryotic translation initiation factor 3 complex	10	2.67e-02	0.405	2.64e-01
GO:0048041 focal adhesion assembly	14	8.82e-03	-0.404	1.71e-01
GO:0051010 microtubule plus-end binding	11	2.03e-02	0.404	2.31e-01
GO:0005544 calcium-dependent phospholipid binding	21	1.40e-03	0.403	7.61e-02
GO:0017056 structural constituent of nuclear pore	19	2.67e-03	-0.398	1.01e-01
GO:0098869 cellular oxidant detoxification	28	3.20e-04	0.393	2.84e-02
GO:0032924 activin receptor signaling pathway	12	1.89e-02	-0.391	2.25e-01
GO:0090128 regulation of synapse maturation	11	2.61e-02	0.387	2.62e-01
GO:0045943 positive regulation of transcription by RNA polymerase I	11	2.68e-02	-0.386	2.64e-01
GO:0032585 multivesicular body membrane	12	2.12e-02	0.384	2.36e-01
GO:0032391 photoreceptor connecting cilium	18	4.79e-03	0.384	1.32e-01

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
GO:0000245 spliceosomal complex assembly	10	6.52e-05	-7.29e-01	8.62e-03
GO:0022625 cytosolic large ribosomal subunit	40	1.17e-12	6.49e-01	1.93e-09
GO:0035145 exon-exon junction complex	10	4.12e-04	-6.45e-01	3.32e-02
GO:0022627 cytosolic small ribosomal subunit	25	4.96e-07	5.81e-01	2.93e-04
GO:0030127 COPII vesicle coat	10	2.01e-03	5.64e-01	8.90e-02
GO:1905564 positive regulation of vascular endothelial cell proliferation	10	2.18e-03	5.60e-01	8.99e-02
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway	11	1.61e-03	5.49e-01	7.93e-02
GO:1903076 regulation of protein localization to plasma membrane	18	6.63e-05	5.43e-01	8.62e-03
GO:0002181 cytoplasmic translation	27	1.69e-06	5.32e-01	6.31e-04
GO:1903077 negative regulation of protein localization to plasma membrane	13	1.02e-03	5.26e-01	6.22e-02
GO:0004364 glutathione transferase activity	10	5.73e-03	5.05e-01	1.41e-01
GO:0004602 glutathione peroxidase activity	12	2.53e-03	5.03e-01	9.74e-02
GO:0071353 cellular response to interleukin-4	10	5.92e-03	5.03e-01	1.41e-01
GO:0004683 calcium/calmodulin-dependent protein kinase activity	11	5.60e-03	4.82e-01	1.41e-01
GO:0044322 endoplasmic reticulum quality control compartment	11	5.84e-03	4.80e-01	1.41e-01
GO:0051642 centrosome localization	14	1.91e-03	4.79e-01	8.65e-02
GO:0007017 microtubule-based process	11	5.97e-03	4.79e-01	1.41e-01
GO:0030020 extracellular matrix structural constituent conferring tensile strength	16	1.00e-03	4.75e-01	6.22e-02
GO:0030100 regulation of endocytosis	12	4.77e-03	4.71e-01	1.32e-01
GO:0008593 regulation of Notch signaling pathway	10	1.17e-02	4.60e-01	1.79e-01
GO:0140662 ATP-dependent protein folding chaperone	23	1.49e-04	-4.57e-01	1.63e-02
GO:0035925 mRNA 3’-UTR AU-rich region binding	13	4.61e-03	4.54e-01	1.32e-01
GO:0090110 COPII-coated vesicle cargo loading	10	1.33e-02	4.52e-01	1.93e-01
GO:0005791 rough endoplasmic reticulum	12	7.86e-03	-4.43e-01	1.63e-01
GO:0044458 motile cilium assembly	12	7.93e-03	4.43e-01	1.63e-01
GO:1902774 late endosome to lysosome transport	10	1.56e-02	4.42e-01	2.06e-01
GO:0030863 cortical cytoskeleton	10	1.71e-02	4.35e-01	2.21e-01
GO:0030992 intraciliary transport particle B	15	3.92e-03	4.30e-01	1.25e-01
GO:0043995 histone H4K5 acetyltransferase activity	10	1.98e-02	-4.25e-01	2.30e-01
GO:0043996 histone H4K8 acetyltransferase activity	10	1.98e-02	-4.25e-01	2.30e-01
GO:0001772 immunological synapse	22	5.90e-04	4.23e-01	4.02e-02
GO:0043997 histone H4K12 acetyltransferase activity	10	2.07e-02	-4.22e-01	2.32e-01
GO:0061952 midbody abscission	14	7.55e-03	4.12e-01	1.63e-01
GO:0048018 receptor ligand activity	18	2.46e-03	-4.12e-01	9.66e-02
GO:0003724 RNA helicase activity	37	1.49e-05	-4.11e-01	3.30e-03
GO:0070182 DNA polymerase binding	13	1.03e-02	-4.11e-01	1.79e-01
GO:0060395 SMAD protein signal transduction	14	8.29e-03	-4.08e-01	1.69e-01
GO:0040029 epigenetic regulation of gene expression	18	2.79e-03	-4.07e-01	1.03e-01
GO:0032968 positive regulation of transcription elongation by RNA polymerase II	15	6.45e-03	-4.06e-01	1.50e-01
GO:0005852 eukaryotic translation initiation factor 3 complex	10	2.67e-02	4.05e-01	2.64e-01
GO:0048041 focal adhesion assembly	14	8.82e-03	-4.04e-01	1.71e-01
GO:0051010 microtubule plus-end binding	11	2.03e-02	4.04e-01	2.31e-01
GO:0005544 calcium-dependent phospholipid binding	21	1.40e-03	4.03e-01	7.61e-02
GO:0017056 structural constituent of nuclear pore	19	2.67e-03	-3.98e-01	1.01e-01
GO:0098869 cellular oxidant detoxification	28	3.20e-04	3.93e-01	2.84e-02
GO:0032924 activin receptor signaling pathway	12	1.89e-02	-3.91e-01	2.25e-01
GO:0090128 regulation of synapse maturation	11	2.61e-02	3.87e-01	2.62e-01
GO:0045943 positive regulation of transcription by RNA polymerase I	11	2.68e-02	-3.86e-01	2.64e-01
GO:0032585 multivesicular body membrane	12	2.12e-02	3.84e-01	2.36e-01
GO:0032391 photoreceptor connecting cilium	18	4.79e-03	3.84e-01	1.32e-01
GO:0070131 positive regulation of mitochondrial translation	10	3.58e-02	-3.83e-01	2.88e-01
GO:0006641 triglyceride metabolic process	10	3.58e-02	3.83e-01	2.88e-01
GO:0140658 ATP-dependent chromatin remodeler activity	11	2.82e-02	-3.82e-01	2.66e-01
GO:0046875 ephrin receptor binding	17	6.84e-03	3.79e-01	1.53e-01
GO:0006749 glutathione metabolic process	15	1.12e-02	3.78e-01	1.79e-01
GO:1904294 positive regulation of ERAD pathway	10	3.85e-02	3.78e-01	2.93e-01
GO:0022604 regulation of cell morphogenesis	14	1.45e-02	-3.77e-01	1.99e-01
GO:0001917 photoreceptor inner segment	23	1.85e-03	3.75e-01	8.65e-02
GO:0140416 transcription regulator inhibitor activity	12	2.46e-02	-3.75e-01	2.59e-01
GO:0003735 structural constituent of ribosome	118	2.18e-12	3.74e-01	1.93e-09
GO:0060216 definitive hemopoiesis	10	4.03e-02	3.74e-01	3.00e-01
GO:0035770 ribonucleoprotein granule	13	1.95e-02	-3.74e-01	2.28e-01
GO:0030665 clathrin-coated vesicle membrane	11	3.18e-02	3.74e-01	2.77e-01
GO:0097225 sperm midpiece	14	1.55e-02	3.74e-01	2.06e-01
GO:2000648 positive regulation of stem cell proliferation	12	2.52e-02	3.73e-01	2.62e-01
GO:0007218 neuropeptide signaling pathway	16	9.88e-03	3.73e-01	1.77e-01
GO:0140326 ATPase-coupled intramembrane lipid transporter activity	11	3.34e-02	3.71e-01	2.80e-01
GO:0045332 phospholipid translocation	16	1.08e-02	3.68e-01	1.79e-01
GO:2000377 regulation of reactive oxygen species metabolic process	10	4.39e-02	3.68e-01	3.13e-01
GO:0000774 adenyl-nucleotide exchange factor activity	12	2.74e-02	-3.68e-01	2.65e-01
GO:0042026 protein refolding	12	2.76e-02	-3.67e-01	2.65e-01
GO:0042056 chemoattractant activity	11	3.51e-02	3.67e-01	2.87e-01
GO:0051489 regulation of filopodium assembly	10	4.59e-02	3.65e-01	3.16e-01
GO:0006936 muscle contraction	10	4.60e-02	-3.64e-01	3.16e-01
GO:0010839 negative regulation of keratinocyte proliferation	14	1.84e-02	3.64e-01	2.25e-01
GO:0042572 retinol metabolic process	13	2.39e-02	3.62e-01	2.55e-01
GO:0060291 long-term synaptic potentiation	10	4.84e-02	-3.61e-01	3.19e-01
GO:0007162 negative regulation of cell adhesion	17	1.07e-02	-3.58e-01	1.79e-01
GO:0001675 acrosome assembly	11	4.19e-02	3.54e-01	3.04e-01
GO:0010977 negative regulation of neuron projection development	17	1.15e-02	-3.54e-01	1.79e-01
GO:0071108 protein K48-linked deubiquitination	15	1.79e-02	-3.53e-01	2.25e-01
GO:0000077 DNA damage checkpoint signaling	26	1.86e-03	-3.53e-01	8.65e-02
GO:0030904 retromer complex	15	1.84e-02	3.52e-01	2.25e-01
GO:0060349 bone morphogenesis	12	3.58e-02	3.50e-01	2.88e-01
GO:1904646 cellular response to amyloid-beta	10	5.58e-02	3.49e-01	3.37e-01
GO:0005680 anaphase-promoting complex	13	2.94e-02	-3.49e-01	2.70e-01
GO:0097038 perinuclear endoplasmic reticulum	10	5.62e-02	3.49e-01	3.37e-01
GO:0030866 cortical actin cytoskeleton organization	20	7.04e-03	3.48e-01	1.55e-01
GO:0008137 NADH dehydrogenase (ubiquinone) activity	10	5.68e-02	3.48e-01	3.37e-01
GO:0004860 protein kinase inhibitor activity	19	8.84e-03	3.47e-01	1.71e-01
GO:0006622 protein targeting to lysosome	15	2.05e-02	3.46e-01	2.31e-01
GO:0051287 NAD binding	18	1.16e-02	3.44e-01	1.79e-01
GO:0016757 glycosyltransferase activity	14	2.60e-02	-3.44e-01	2.62e-01
GO:2000352 negative regulation of endothelial cell apoptotic process	14	2.75e-02	3.40e-01	2.65e-01
GO:0031623 receptor internalization	21	7.10e-03	3.39e-01	1.55e-01
GO:0015701 bicarbonate transport	11	5.22e-02	-3.38e-01	3.33e-01
GO:0045216 cell-cell junction organization	13	3.49e-02	-3.38e-01	2.87e-01
GO:0002218 activation of innate immune response	17	1.77e-02	-3.32e-01	2.25e-01
GO:0002102 podosome	18	1.48e-02	3.32e-01	2.00e-01
GO:0016829 lyase activity	15	2.65e-02	3.31e-01	2.64e-01
GO:0006468 protein phosphorylation	12	4.81e-02	-3.30e-01	3.19e-01
GO:0005774 vacuolar membrane	10	7.14e-02	3.29e-01	3.62e-01
GO:0033617 mitochondrial cytochrome c oxidase assembly	13	4.09e-02	-3.27e-01	3.02e-01
GO:0043616 keratinocyte proliferation	11	6.02e-02	3.27e-01	3.46e-01
GO:0050808 synapse organization	16	2.38e-02	-3.27e-01	2.55e-01
GO:0031982 vesicle	27	3.50e-03	3.25e-01	1.17e-01
GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	12	5.21e-02	-3.24e-01	3.33e-01
GO:0007042 lysosomal lumen acidification	10	7.68e-02	3.23e-01	3.68e-01
GO:0046961 proton-transporting ATPase activity, rotational mechanism	14	3.63e-02	3.23e-01	2.89e-01
GO:0070577 lysine-acetylated histone binding	16	2.55e-02	-3.23e-01	2.62e-01
GO:0016236 macroautophagy	16	2.60e-02	3.22e-01	2.62e-01
GO:0070411 I-SMAD binding	11	6.58e-02	-3.20e-01	3.60e-01
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle	14	3.84e-02	-3.20e-01	2.93e-01
GO:0045116 protein neddylation	10	8.27e-02	3.17e-01	3.84e-01
GO:0018279 protein N-linked glycosylation via asparagine	11	6.95e-02	3.16e-01	3.62e-01
GO:0051592 response to calcium ion	20	1.47e-02	3.15e-01	2.00e-01
GO:0007339 binding of sperm to zona pellucida	11	7.04e-02	-3.15e-01	3.62e-01
GO:0051371 muscle alpha-actinin binding	10	8.53e-02	-3.14e-01	3.91e-01
GO:0061512 protein localization to cilium	22	1.14e-02	3.11e-01	1.79e-01
GO:0060170 ciliary membrane	21	1.36e-02	3.11e-01	1.94e-01
GO:0043484 regulation of RNA splicing	23	9.82e-03	-3.11e-01	1.77e-01
GO:0043024 ribosomal small subunit binding	13	5.22e-02	-3.11e-01	3.33e-01
GO:0030030 cell projection organization	13	5.26e-02	3.10e-01	3.33e-01
GO:0030687 preribosome, large subunit precursor	12	6.27e-02	-3.10e-01	3.53e-01
GO:0007163 establishment or maintenance of cell polarity	13	5.28e-02	3.10e-01	3.33e-01
GO:0070971 endoplasmic reticulum exit site	19	1.93e-02	3.10e-01	2.27e-01
GO:0070507 regulation of microtubule cytoskeleton organization	14	4.46e-02	3.10e-01	3.14e-01
GO:0045739 positive regulation of DNA repair	20	1.66e-02	-3.10e-01	2.18e-01
GO:0051881 regulation of mitochondrial membrane potential	14	4.54e-02	-3.09e-01	3.15e-01
GO:0005815 microtubule organizing center	37	1.18e-03	3.08e-01	6.76e-02
GO:0140861 DNA repair-dependent chromatin remodeling	14	4.63e-02	-3.08e-01	3.17e-01
GO:0048027 mRNA 5’-UTR binding	19	2.05e-02	3.07e-01	2.31e-01
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	13	5.60e-02	-3.06e-01	3.37e-01
GO:0034707 chloride channel complex	11	7.94e-02	3.05e-01	3.76e-01
GO:0045292 mRNA cis splicing, via spliceosome	13	5.66e-02	-3.05e-01	3.37e-01
GO:0051603 proteolysis involved in protein catabolic process	22	1.33e-02	3.05e-01	1.93e-01
GO:0034727 piecemeal microautophagy of the nucleus	13	5.69e-02	3.05e-01	3.37e-01
GO:0070034 telomerase RNA binding	12	6.75e-02	-3.05e-01	3.62e-01
GO:0001958 endochondral ossification	15	4.11e-02	3.05e-01	3.02e-01
GO:0009888 tissue development	18	2.54e-02	-3.04e-01	2.62e-01
GO:0016442 RISC complex	11	8.07e-02	-3.04e-01	3.77e-01
GO:0030017 sarcomere	13	5.80e-02	3.04e-01	3.41e-01
GO:0030316 osteoclast differentiation	29	4.69e-03	-3.03e-01	1.32e-01
GO:1903543 positive regulation of exosomal secretion	10	9.85e-02	3.02e-01	4.19e-01
GO:0006979 response to oxidative stress	50	2.28e-04	3.01e-01	2.12e-02
GO:0005665 RNA polymerase II, core complex	10	9.89e-02	3.01e-01	4.19e-01
GO:0031663 lipopolysaccharide-mediated signaling pathway	10	1.00e-01	3.00e-01	4.21e-01
GO:0090316 positive regulation of intracellular protein transport	14	5.24e-02	2.99e-01	3.33e-01
GO:0005828 kinetochore microtubule	10	1.01e-01	2.99e-01	4.21e-01
GO:0060379 cardiac muscle cell myoblast differentiation	10	1.03e-01	-2.98e-01	4.23e-01
GO:0015030 Cajal body	26	8.86e-03	-2.97e-01	1.71e-01
GO:0050840 extracellular matrix binding	16	4.11e-02	2.95e-01	3.02e-01
GO:0032728 positive regulation of interferon-beta production	15	4.84e-02	-2.94e-01	3.19e-01
GO:0030515 snoRNA binding	14	5.66e-02	-2.94e-01	3.37e-01
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage	24	1.33e-02	-2.92e-01	1.93e-01
GO:0007601 visual perception	39	1.60e-03	2.92e-01	7.93e-02
GO:0051233 spindle midzone	17	3.79e-02	2.91e-01	2.93e-01
GO:0000423 mitophagy	31	5.08e-03	2.91e-01	1.32e-01
GO:0033290 eukaryotic 48S preinitiation complex	13	7.00e-02	2.90e-01	3.62e-01
GO:0046847 filopodium assembly	10	1.12e-01	2.90e-01	4.41e-01
GO:0035869 ciliary transition zone	22	1.90e-02	2.89e-01	2.25e-01
GO:0051393 alpha-actinin binding	10	1.14e-01	-2.89e-01	4.43e-01
GO:0141198 protein branched polyubiquitination	13	7.17e-02	-2.89e-01	3.62e-01
GO:0038061 non-canonical NF-kappaB signal transduction	11	9.77e-02	-2.88e-01	4.18e-01
GO:0004888 transmembrane signaling receptor activity	24	1.45e-02	2.88e-01	1.99e-01
GO:0031145 anaphase-promoting complex-dependent catabolic process	14	6.26e-02	-2.87e-01	3.53e-01
GO:0140672 ATAC complex	11	9.89e-02	-2.87e-01	4.19e-01
GO:0017018 myosin phosphatase activity	13	7.35e-02	-2.87e-01	3.62e-01
GO:0140791 histone H2AXS140 phosphatase activity	13	7.35e-02	-2.87e-01	3.62e-01
GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	13	7.35e-02	-2.87e-01	3.62e-01
GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	13	7.35e-02	-2.87e-01	3.62e-01
GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	13	7.35e-02	-2.87e-01	3.62e-01
GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	13	7.35e-02	-2.87e-01	3.62e-01
GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	13	7.35e-02	-2.87e-01	3.62e-01
GO:1990439 MAP kinase serine/threonine phosphatase activity	13	7.35e-02	-2.87e-01	3.62e-01
GO:0045931 positive regulation of mitotic cell cycle	14	6.33e-02	2.87e-01	3.54e-01
GO:0009953 dorsal/ventral pattern formation	16	4.73e-02	-2.87e-01	3.19e-01
GO:0009968 negative regulation of signal transduction	14	6.43e-02	2.86e-01	3.56e-01
GO:1990391 DNA repair complex	10	1.18e-01	-2.85e-01	4.50e-01
GO:0006406 mRNA export from nucleus	28	9.05e-03	-2.85e-01	1.71e-01
GO:0071577 zinc ion transmembrane transport	10	1.19e-01	-2.85e-01	4.50e-01
GO:0016601 Rac protein signal transduction	17	4.28e-02	2.84e-01	3.09e-01
GO:0001662 behavioral fear response	12	8.89e-02	2.84e-01	4.00e-01
GO:0008542 visual learning	20	2.84e-02	2.83e-01	2.66e-01
GO:0006412 translation	96	1.78e-06	2.82e-01	6.31e-04
GO:0007099 centriole replication	13	7.80e-02	2.82e-01	3.74e-01
GO:0050679 positive regulation of epithelial cell proliferation	20	2.90e-02	-2.82e-01	2.70e-01
GO:0044295 axonal growth cone	10	1.23e-01	-2.82e-01	4.55e-01
GO:0007623 circadian rhythm	18	3.86e-02	2.82e-01	2.93e-01
GO:0061351 neural precursor cell proliferation	14	6.82e-02	-2.82e-01	3.62e-01
GO:0055074 calcium ion homeostasis	17	4.47e-02	2.81e-01	3.14e-01
GO:0043153 entrainment of circadian clock by photoperiod	13	8.00e-02	-2.80e-01	3.77e-01
GO:0051491 positive regulation of filopodium assembly	15	6.01e-02	-2.80e-01	3.46e-01
GO:0001732 formation of cytoplasmic translation initiation complex	12	9.40e-02	2.79e-01	4.10e-01
GO:0012506 vesicle membrane	15	6.15e-02	2.79e-01	3.49e-01
GO:0032012 regulation of ARF protein signal transduction	14	7.18e-02	2.78e-01	3.62e-01
GO:0035994 response to muscle stretch	10	1.28e-01	-2.78e-01	4.60e-01
GO:0035267 NuA4 histone acetyltransferase complex	18	4.16e-02	-2.77e-01	3.04e-01
GO:0032755 positive regulation of interleukin-6 production	31	7.67e-03	2.77e-01	1.63e-01
GO:0043409 negative regulation of MAPK cascade	20	3.23e-02	-2.77e-01	2.78e-01
GO:2001222 regulation of neuron migration	10	1.30e-01	2.76e-01	4.66e-01
GO:0007026 negative regulation of microtubule depolymerization	17	4.88e-02	2.76e-01	3.20e-01
GO:0038202 TORC1 signaling	12	9.79e-02	2.76e-01	4.18e-01
GO:0070412 R-SMAD binding	13	8.52e-02	-2.76e-01	3.91e-01
GO:0045177 apical part of cell	35	4.88e-03	2.75e-01	1.32e-01
GO:0030170 pyridoxal phosphate binding	34	5.72e-03	2.74e-01	1.41e-01
GO:0006096 glycolytic process	23	2.31e-02	2.74e-01	2.51e-01
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	21	3.02e-02	-2.73e-01	2.70e-01
GO:0048488 synaptic vesicle endocytosis	20	3.47e-02	2.73e-01	2.87e-01
GO:0003925 G protein activity	18	4.52e-02	2.73e-01	3.15e-01
GO:0051315 attachment of mitotic spindle microtubules to kinetochore	10	1.37e-01	2.72e-01	4.69e-01
GO:0009925 basal plasma membrane	11	1.19e-01	2.71e-01	4.51e-01
GO:0008266 poly(U) RNA binding	16	6.07e-02	2.71e-01	3.47e-01
GO:0000974 Prp19 complex	10	1.39e-01	-2.71e-01	4.69e-01
GO:0005840 ribosome	43	2.18e-03	2.70e-01	8.99e-02
GO:0098656 monoatomic anion transmembrane transport	18	4.75e-02	-2.70e-01	3.19e-01
GO:0090102 cochlea development	12	1.06e-01	2.69e-01	4.33e-01
GO:0044782 cilium organization	13	9.30e-02	2.69e-01	4.10e-01
GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site	16	6.28e-02	2.69e-01	3.53e-01
GO:0006730 one-carbon metabolic process	13	9.36e-02	2.69e-01	4.10e-01
GO:0000421 autophagosome membrane	23	2.59e-02	2.68e-01	2.62e-01
GO:0035278 miRNA-mediated gene silencing by inhibition of translation	13	9.48e-02	-2.68e-01	4.12e-01
GO:0045740 positive regulation of DNA replication	11	1.25e-01	-2.67e-01	4.56e-01
GO:0030658 transport vesicle membrane	13	9.61e-02	2.67e-01	4.15e-01
GO:0008305 integrin complex	15	7.43e-02	2.66e-01	3.62e-01
GO:0005902 microvillus	28	1.52e-02	2.65e-01	2.03e-01
GO:0030057 desmosome	12	1.12e-01	-2.65e-01	4.41e-01
GO:0071346 cellular response to type II interferon	23	2.79e-02	2.65e-01	2.65e-01
GO:0008047 enzyme activator activity	15	7.62e-02	-2.64e-01	3.68e-01
GO:0002224 toll-like receptor signaling pathway	14	8.79e-02	2.63e-01	3.98e-01
GO:0071549 cellular response to dexamethasone stimulus	11	1.31e-01	2.63e-01	4.67e-01
GO:0031468 nuclear membrane reassembly	11	1.32e-01	2.62e-01	4.69e-01
GO:0001750 photoreceptor outer segment	23	2.98e-02	2.62e-01	2.70e-01
GO:0030522 intracellular receptor signaling pathway	18	5.46e-02	-2.62e-01	3.37e-01
GO:1990166 protein localization to site of double-strand break	10	1.52e-01	2.62e-01	4.97e-01
GO:0006913 nucleocytoplasmic transport	18	5.49e-02	-2.61e-01	3.37e-01
GO:0020037 heme binding	50	1.46e-03	2.60e-01	7.61e-02
GO:0071711 basement membrane organization	11	1.35e-01	2.60e-01	4.69e-01
GO:0046849 bone remodeling	10	1.55e-01	-2.60e-01	5.00e-01
GO:0048306 calcium-dependent protein binding	20	4.44e-02	2.60e-01	3.14e-01
GO:1904262 negative regulation of TORC1 signaling	28	1.75e-02	2.59e-01	2.25e-01
GO:0005771 multivesicular body	21	3.98e-02	2.59e-01	2.99e-01
GO:2001235 positive regulation of apoptotic signaling pathway	16	7.33e-02	2.59e-01	3.62e-01
GO:0007389 pattern specification process	14	9.40e-02	2.59e-01	4.10e-01
GO:0017124 SH3 domain binding	43	3.40e-03	2.58e-01	1.16e-01
GO:2000378 negative regulation of reactive oxygen species metabolic process	10	1.58e-01	2.58e-01	5.06e-01
GO:0036064 ciliary basal body	103	6.69e-06	2.57e-01	1.69e-03
GO:0005249 voltage-gated potassium channel activity	14	9.75e-02	-2.56e-01	4.18e-01
GO:0030513 positive regulation of BMP signaling pathway	20	4.78e-02	-2.56e-01	3.19e-01
GO:0036121 double-stranded DNA helicase activity	11	1.42e-01	-2.55e-01	4.76e-01
GO:0071005 U2-type precatalytic spliceosome	31	1.40e-02	-2.55e-01	1.96e-01
GO:0006120 mitochondrial electron transport, NADH to ubiquinone	19	5.42e-02	2.55e-01	3.37e-01
GO:0048701 embryonic cranial skeleton morphogenesis	13	1.12e-01	2.55e-01	4.41e-01
GO:0007214 gamma-aminobutyric acid signaling pathway	11	1.44e-01	2.54e-01	4.79e-01
GO:0050829 defense response to Gram-negative bacterium	12	1.28e-01	2.54e-01	4.60e-01
GO:0001819 positive regulation of cytokine production	13	1.14e-01	2.53e-01	4.43e-01
GO:0007076 mitotic chromosome condensation	10	1.66e-01	2.53e-01	5.17e-01
GO:0035102 PRC1 complex	13	1.14e-01	-2.53e-01	4.43e-01
GO:0048167 regulation of synaptic plasticity	16	8.05e-02	-2.52e-01	3.77e-01
GO:0001725 stress fiber	42	4.70e-03	-2.52e-01	1.32e-01
GO:0000987 cis-regulatory region sequence-specific DNA binding	21	4.55e-02	-2.52e-01	3.15e-01
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	17	7.28e-02	-2.51e-01	3.62e-01
GO:0043687 post-translational protein modification	19	5.88e-02	2.50e-01	3.44e-01
GO:0005905 clathrin-coated pit	30	1.79e-02	2.50e-01	2.25e-01
GO:0019003 GDP binding	44	4.24e-03	2.49e-01	1.29e-01
GO:0015914 phospholipid transport	26	2.82e-02	2.49e-01	2.66e-01
GO:0005049 nuclear export signal receptor activity	10	1.74e-01	-2.48e-01	5.32e-01
GO:0000422 autophagy of mitochondrion	14	1.08e-01	2.48e-01	4.37e-01
GO:0000400 four-way junction DNA binding	14	1.09e-01	2.47e-01	4.37e-01
GO:0007492 endoderm development	10	1.76e-01	-2.47e-01	5.35e-01
GO:0042073 intraciliary transport	16	8.84e-02	2.46e-01	3.99e-01
GO:0030742 GTP-dependent protein binding	13	1.25e-01	2.46e-01	4.55e-01
GO:0045271 respiratory chain complex I	31	1.80e-02	2.46e-01	2.25e-01
GO:0001974 blood vessel remodeling	17	8.03e-02	2.45e-01	3.77e-01
GO:0031929 TOR signaling	13	1.26e-01	2.45e-01	4.56e-01
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding	41	6.80e-03	2.44e-01	1.53e-01
GO:0071539 protein localization to centrosome	20	5.94e-02	2.44e-01	3.44e-01
GO:0031032 actomyosin structure organization	17	8.30e-02	2.43e-01	3.85e-01
GO:0034314 Arp2/3 complex-mediated actin nucleation	11	1.63e-01	2.43e-01	5.13e-01
GO:0005005 transmembrane-ephrin receptor activity	14	1.16e-01	-2.43e-01	4.47e-01
GO:0021987 cerebral cortex development	25	3.62e-02	2.42e-01	2.89e-01
GO:0050661 NADP binding	15	1.06e-01	2.41e-01	4.33e-01
GO:0008023 transcription elongation factor complex	14	1.19e-01	-2.41e-01	4.50e-01
GO:0043240 Fanconi anaemia nuclear complex	11	1.67e-01	2.40e-01	5.20e-01
GO:0042169 SH2 domain binding	20	6.30e-02	2.40e-01	3.53e-01
GO:0031462 Cul2-RING ubiquitin ligase complex	15	1.09e-01	-2.39e-01	4.37e-01
GO:0005689 U12-type spliceosomal complex	20	6.45e-02	-2.39e-01	3.56e-01
GO:0031681 G-protein beta-subunit binding	10	1.92e-01	2.38e-01	5.61e-01
GO:0097352 autophagosome maturation	23	4.79e-02	2.38e-01	3.19e-01
GO:0030016 myofibril	13	1.37e-01	-2.38e-01	4.69e-01
GO:0030331 nuclear estrogen receptor binding	19	7.23e-02	-2.38e-01	3.62e-01
GO:0006805 xenobiotic metabolic process	17	8.95e-02	2.38e-01	4.02e-01
GO:0080008 Cul4-RING E3 ubiquitin ligase complex	13	1.38e-01	-2.37e-01	4.69e-01
GO:0035371 microtubule plus-end	12	1.55e-01	2.37e-01	5.00e-01
GO:0071897 DNA biosynthetic process	12	1.55e-01	-2.37e-01	5.00e-01
GO:1905515 non-motile cilium assembly	39	1.04e-02	2.37e-01	1.79e-01
GO:0006623 protein targeting to vacuole	11	1.74e-01	-2.37e-01	5.32e-01
GO:0015631 tubulin binding	28	3.02e-02	2.37e-01	2.70e-01
GO:0050768 negative regulation of neurogenesis	10	1.95e-01	-2.37e-01	5.62e-01
GO:0009408 response to heat	19	7.43e-02	-2.37e-01	3.62e-01
GO:0098761 cellular response to interleukin-7	10	1.95e-01	-2.37e-01	5.62e-01
GO:0010718 positive regulation of epithelial to mesenchymal transition	26	3.70e-02	-2.36e-01	2.90e-01
GO:0014704 intercalated disc	14	1.26e-01	2.36e-01	4.56e-01
GO:0070006 metalloaminopeptidase activity	15	1.14e-01	2.36e-01	4.43e-01
GO:0071480 cellular response to gamma radiation	14	1.27e-01	-2.36e-01	4.56e-01
GO:0007259 cell surface receptor signaling pathway via JAK-STAT	22	5.61e-02	2.35e-01	3.37e-01
GO:0002230 positive regulation of defense response to virus by host	11	1.77e-01	-2.35e-01	5.35e-01
GO:0051219 phosphoprotein binding	20	6.90e-02	2.35e-01	3.62e-01
GO:0007612 learning	13	1.43e-01	-2.35e-01	4.77e-01
GO:1900181 negative regulation of protein localization to nucleus	11	1.80e-01	-2.34e-01	5.38e-01
GO:0005901 caveola	28	3.30e-02	2.33e-01	2.78e-01
GO:0031175 neuron projection development	49	5.07e-03	-2.32e-01	1.32e-01
GO:0097730 non-motile cilium	16	1.09e-01	2.31e-01	4.37e-01
GO:1901223 negative regulation of non-canonical NF-kappaB signal transduction	14	1.34e-01	2.31e-01	4.69e-01
GO:0033627 cell adhesion mediated by integrin	20	7.37e-02	2.31e-01	3.62e-01
GO:0005009 insulin receptor activity	14	1.37e-01	-2.30e-01	4.69e-01
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation	14	1.37e-01	-2.29e-01	4.69e-01
GO:0071007 U2-type catalytic step 2 spliceosome	24	5.22e-02	-2.29e-01	3.33e-01
GO:0030900 forebrain development	20	7.67e-02	-2.29e-01	3.68e-01
GO:0006368 transcription elongation by RNA polymerase II	24	5.27e-02	-2.29e-01	3.33e-01
GO:0030199 collagen fibril organization	30	3.04e-02	2.28e-01	2.70e-01
GO:0070498 interleukin-1-mediated signaling pathway	11	1.90e-01	2.28e-01	5.59e-01
GO:0051480 regulation of cytosolic calcium ion concentration	13	1.54e-01	2.28e-01	5.00e-01
GO:0005801 cis-Golgi network	28	3.68e-02	2.28e-01	2.90e-01
GO:0043565 sequence-specific DNA binding	57	2.98e-03	-2.28e-01	1.05e-01
GO:0005811 lipid droplet	42	1.08e-02	2.27e-01	1.79e-01
GO:0035914 skeletal muscle cell differentiation	24	5.43e-02	-2.27e-01	3.37e-01
GO:0030276 clathrin binding	17	1.07e-01	2.26e-01	4.34e-01
GO:0032729 positive regulation of type II interferon production	21	7.39e-02	2.25e-01	3.62e-01
GO:0030159 signaling receptor complex adaptor activity	13	1.60e-01	2.25e-01	5.09e-01
GO:0006633 fatty acid biosynthetic process	22	6.81e-02	2.25e-01	3.62e-01
GO:0005777 peroxisome	49	6.55e-03	2.25e-01	1.51e-01
GO:0032570 response to progesterone	13	1.62e-01	-2.24e-01	5.11e-01
GO:0001501 skeletal system development	34	2.40e-02	2.24e-01	2.55e-01
GO:0045070 positive regulation of viral genome replication	19	9.15e-02	-2.24e-01	4.08e-01
GO:0030141 secretory granule	18	1.01e-01	2.24e-01	4.21e-01
GO:0071277 cellular response to calcium ion	31	3.14e-02	2.23e-01	2.75e-01
GO:0000380 alternative mRNA splicing, via spliceosome	16	1.22e-01	-2.23e-01	4.54e-01
GO:0051894 positive regulation of focal adhesion assembly	15	1.34e-01	2.23e-01	4.69e-01
GO:0043495 protein-membrane adaptor activity	17	1.12e-01	2.23e-01	4.41e-01
GO:0048255 mRNA stabilization	16	1.24e-01	-2.22e-01	4.55e-01
GO:0004693 cyclin-dependent protein serine/threonine kinase activity	10	2.26e-01	2.21e-01	6.06e-01
GO:0000070 mitotic sister chromatid segregation	18	1.06e-01	2.20e-01	4.33e-01
GO:0005871 kinesin complex	22	7.37e-02	2.20e-01	3.62e-01
GO:0007405 neuroblast proliferation	21	8.06e-02	2.20e-01	3.77e-01
GO:0007052 mitotic spindle organization	34	2.64e-02	2.20e-01	2.64e-01
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway	14	1.55e-01	-2.19e-01	5.00e-01
GO:0055037 recycling endosome	56	4.53e-03	2.19e-01	1.32e-01
GO:0031334 positive regulation of protein-containing complex assembly	17	1.18e-01	2.19e-01	4.50e-01
GO:0034599 cellular response to oxidative stress	44	1.21e-02	2.19e-01	1.83e-01
GO:0050918 positive chemotaxis	13	1.73e-01	2.18e-01	5.32e-01
GO:0005795 Golgi stack	18	1.09e-01	2.18e-01	4.37e-01
GO:0060045 positive regulation of cardiac muscle cell proliferation	13	1.75e-01	-2.17e-01	5.33e-01
GO:0044331 cell-cell adhesion mediated by cadherin	12	1.94e-01	2.17e-01	5.61e-01
GO:0060047 heart contraction	10	2.36e-01	2.17e-01	6.12e-01
GO:0046854 phosphatidylinositol phosphate biosynthetic process	18	1.12e-01	-2.16e-01	4.41e-01
GO:1902895 positive regulation of miRNA transcription	25	6.13e-02	-2.16e-01	3.49e-01
GO:0071560 cellular response to transforming growth factor beta stimulus	16	1.35e-01	2.16e-01	4.69e-01
GO:0034451 centriolar satellite	73	1.43e-03	2.16e-01	7.61e-02
GO:0005044 scavenger receptor activity	10	2.37e-01	2.16e-01	6.12e-01
GO:0032757 positive regulation of interleukin-8 production	16	1.35e-01	2.16e-01	4.69e-01
GO:0000281 mitotic cytokinesis	34	2.97e-02	2.16e-01	2.70e-01
GO:0034045 phagophore assembly site membrane	12	1.97e-01	2.15e-01	5.65e-01
GO:0017166 vinculin binding	10	2.41e-01	-2.14e-01	6.16e-01
GO:0000775 chromosome, centromeric region	31	3.92e-02	2.14e-01	2.97e-01
GO:0030041 actin filament polymerization	16	1.39e-01	2.14e-01	4.71e-01
GO:0030225 macrophage differentiation	11	2.21e-01	2.13e-01	5.96e-01
GO:1990841 promoter-specific chromatin binding	34	3.19e-02	-2.13e-01	2.77e-01
GO:0030855 epithelial cell differentiation	29	4.78e-02	2.12e-01	3.19e-01
GO:0010508 positive regulation of autophagy	39	2.23e-02	2.12e-01	2.45e-01
GO:0048009 insulin-like growth factor receptor signaling pathway	31	4.19e-02	-2.11e-01	3.04e-01
GO:0030330 DNA damage response, signal transduction by p53 class mediator	12	2.05e-01	2.11e-01	5.74e-01
GO:0009653 anatomical structure morphogenesis	22	8.66e-02	-2.11e-01	3.95e-01
GO:0006364 rRNA processing	65	3.31e-03	-2.11e-01	1.15e-01
GO:0007224 smoothened signaling pathway	51	9.24e-03	2.11e-01	1.72e-01
GO:0006898 receptor-mediated endocytosis	24	7.40e-02	2.11e-01	3.62e-01
GO:0051321 meiotic cell cycle	21	9.49e-02	-2.11e-01	4.12e-01
GO:0071013 catalytic step 2 spliceosome	52	8.74e-03	-2.10e-01	1.71e-01
GO:0000132 establishment of mitotic spindle orientation	26	6.40e-02	2.10e-01	3.55e-01
GO:0005245 voltage-gated calcium channel activity	11	2.28e-01	2.10e-01	6.09e-01
GO:0043296 apical junction complex	10	2.51e-01	-2.10e-01	6.28e-01
GO:0016973 poly(A)+ mRNA export from nucleus	13	1.92e-01	-2.09e-01	5.61e-01
GO:0030218 erythrocyte differentiation	28	5.66e-02	2.08e-01	3.37e-01
GO:0031210 phosphatidylcholine binding	18	1.27e-01	2.08e-01	4.56e-01
GO:0034394 protein localization to cell surface	17	1.38e-01	-2.08e-01	4.69e-01
GO:0035198 miRNA binding	21	9.99e-02	-2.07e-01	4.21e-01
GO:0001568 blood vessel development	20	1.09e-01	2.07e-01	4.37e-01
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding	21	1.01e-01	2.07e-01	4.21e-01
GO:0032956 regulation of actin cytoskeleton organization	37	2.95e-02	2.07e-01	2.70e-01
GO:0010569 regulation of double-strand break repair via homologous recombination	10	2.57e-01	-2.07e-01	6.38e-01
GO:0045814 negative regulation of gene expression, epigenetic	16	1.52e-01	-2.07e-01	4.97e-01
GO:0046540 U4/U6 x U5 tri-snRNP complex	23	8.66e-02	-2.06e-01	3.95e-01
GO:0043596 nuclear replication fork	10	2.59e-01	2.06e-01	6.39e-01
GO:0010975 regulation of neuron projection development	16	1.53e-01	2.06e-01	5.00e-01
GO:0007018 microtubule-based movement	41	2.24e-02	2.06e-01	2.45e-01
GO:0002682 regulation of immune system process	11	2.37e-01	-2.06e-01	6.12e-01
GO:0031466 Cul5-RING ubiquitin ligase complex	11	2.37e-01	2.06e-01	6.12e-01
GO:0005782 peroxisomal matrix	10	2.60e-01	2.06e-01	6.41e-01
GO:0034142 toll-like receptor 4 signaling pathway	14	1.84e-01	2.05e-01	5.47e-01
GO:0042102 positive regulation of T cell proliferation	10	2.62e-01	-2.05e-01	6.44e-01
GO:0001650 fibrillar center	101	3.97e-04	-2.04e-01	3.32e-02
GO:0072583 clathrin-dependent endocytosis	19	1.24e-01	2.04e-01	4.55e-01
GO:1990518 single-stranded 3’-5’ DNA helicase activity	11	2.42e-01	-2.04e-01	6.18e-01
GO:0008089 anterograde axonal transport	10	2.65e-01	2.04e-01	6.50e-01
GO:0000793 condensed chromosome	13	2.04e-01	-2.03e-01	5.73e-01
GO:0008092 cytoskeletal protein binding	15	1.73e-01	-2.03e-01	5.32e-01
GO:1904019 epithelial cell apoptotic process	13	2.05e-01	2.03e-01	5.74e-01
GO:0051056 regulation of small GTPase mediated signal transduction	16	1.61e-01	2.03e-01	5.10e-01
GO:0006672 ceramide metabolic process	10	2.69e-01	2.02e-01	6.52e-01
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis	14	1.93e-01	2.01e-01	5.61e-01
GO:0051016 barbed-end actin filament capping	15	1.78e-01	2.01e-01	5.35e-01
GO:0001516 prostaglandin biosynthetic process	10	2.71e-01	2.01e-01	6.54e-01
GO:0005008 hepatocyte growth factor receptor activity	13	2.10e-01	-2.01e-01	5.82e-01
GO:0046677 response to antibiotic	13	2.10e-01	2.01e-01	5.82e-01
GO:0016342 catenin complex	14	1.94e-01	2.01e-01	5.61e-01
GO:0060261 positive regulation of transcription initiation by RNA polymerase II	30	5.76e-02	-2.00e-01	3.40e-01
GO:0048872 homeostasis of number of cells	14	1.94e-01	2.00e-01	5.62e-01
GO:0097718 disordered domain specific binding	15	1.80e-01	-2.00e-01	5.38e-01
GO:0015908 fatty acid transport	11	2.51e-01	2.00e-01	6.28e-01
GO:0004197 cysteine-type endopeptidase activity	36	3.82e-02	2.00e-01	2.93e-01
GO:0003725 double-stranded RNA binding	44	2.21e-02	-1.99e-01	2.45e-01
GO:0001935 endothelial cell proliferation	12	2.33e-01	1.99e-01	6.12e-01
GO:0010634 positive regulation of epithelial cell migration	19	1.34e-01	1.99e-01	4.69e-01
GO:0032039 integrator complex	15	1.83e-01	-1.99e-01	5.44e-01
GO:0030426 growth cone	41	2.79e-02	-1.99e-01	2.65e-01
GO:0008380 RNA splicing	47	1.87e-02	-1.98e-01	2.25e-01
GO:0005198 structural molecule activity	38	3.49e-02	1.98e-01	2.87e-01
GO:0030295 protein kinase activator activity	21	1.17e-01	-1.97e-01	4.50e-01
GO:0048813 dendrite morphogenesis	21	1.18e-01	1.97e-01	4.50e-01
GO:0032993 protein-DNA complex	21	1.18e-01	1.97e-01	4.50e-01
GO:0030901 midbrain development	11	2.59e-01	-1.97e-01	6.39e-01
GO:2000042 negative regulation of double-strand break repair via homologous recombination	16	1.75e-01	-1.96e-01	5.33e-01
GO:0008237 metallopeptidase activity	12	2.40e-01	1.96e-01	6.16e-01
GO:0046513 ceramide biosynthetic process	19	1.40e-01	-1.96e-01	4.71e-01
GO:0010212 response to ionizing radiation	24	9.76e-02	-1.95e-01	4.18e-01
GO:0006744 ubiquinone biosynthetic process	11	2.63e-01	1.95e-01	6.45e-01
GO:0097150 neuronal stem cell population maintenance	18	1.52e-01	1.95e-01	4.97e-01
GO:0030968 endoplasmic reticulum unfolded protein response	30	6.56e-02	1.94e-01	3.60e-01
GO:0043425 bHLH transcription factor binding	10	2.88e-01	-1.94e-01	6.74e-01
GO:0043029 T cell homeostasis	13	2.26e-01	-1.94e-01	6.06e-01
GO:0031514 motile cilium	39	3.75e-02	1.93e-01	2.92e-01
GO:0070372 regulation of ERK1 and ERK2 cascade	12	2.49e-01	-1.92e-01	6.27e-01
GO:0070536 protein K63-linked deubiquitination	16	1.83e-01	-1.92e-01	5.44e-01
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	13	2.30e-01	1.92e-01	6.11e-01
GO:0006261 DNA-templated DNA replication	18	1.59e-01	-1.92e-01	5.06e-01
GO:0009615 response to virus	30	6.94e-02	1.92e-01	3.62e-01
GO:0001894 tissue homeostasis	13	2.34e-01	-1.91e-01	6.12e-01
GO:0009982 pseudouridine synthase activity	12	2.52e-01	-1.91e-01	6.30e-01
GO:0008139 nuclear localization sequence binding	13	2.34e-01	-1.91e-01	6.12e-01
GO:0044344 cellular response to fibroblast growth factor stimulus	10	2.96e-01	1.91e-01	6.81e-01
GO:0050890 cognition	18	1.62e-01	1.91e-01	5.10e-01
GO:0034220 monoatomic ion transmembrane transport	20	1.40e-01	1.91e-01	4.71e-01
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding	13	2.35e-01	1.90e-01	6.12e-01
GO:0006816 calcium ion transport	19	1.51e-01	1.90e-01	4.96e-01
GO:0016791 phosphatase activity	15	2.03e-01	-1.90e-01	5.71e-01
GO:0009378 four-way junction helicase activity	13	2.37e-01	-1.90e-01	6.12e-01
GO:0005010 insulin-like growth factor receptor activity	13	2.37e-01	-1.90e-01	6.12e-01
GO:0002040 sprouting angiogenesis	18	1.64e-01	-1.90e-01	5.14e-01
GO:0000307 cyclin-dependent protein kinase holoenzyme complex	21	1.34e-01	1.89e-01	4.69e-01
GO:0045184 establishment of protein localization	17	1.77e-01	1.89e-01	5.35e-01
GO:0022626 cytosolic ribosome	13	2.39e-01	-1.89e-01	6.16e-01
GO:0034504 protein localization to nucleus	20	1.45e-01	-1.89e-01	4.79e-01
GO:0003729 mRNA binding	145	9.14e-05	-1.89e-01	1.08e-02
GO:0046718 symbiont entry into host cell	22	1.27e-01	-1.88e-01	4.56e-01
GO:0035591 signaling adaptor activity	40	4.02e-02	1.88e-01	3.00e-01
GO:0035269 protein O-linked mannosylation	13	2.42e-01	-1.87e-01	6.18e-01
GO:0016180 snRNA processing	10	3.06e-01	-1.87e-01	6.90e-01
GO:0072659 protein localization to plasma membrane	76	4.95e-03	1.87e-01	1.32e-01
GO:0002039 p53 binding	44	3.24e-02	-1.86e-01	2.78e-01
GO:0032266 phosphatidylinositol-3-phosphate binding	32	6.83e-02	1.86e-01	3.62e-01
GO:0048666 neuron development	26	1.00e-01	-1.86e-01	4.21e-01
GO:0042130 negative regulation of T cell proliferation	12	2.66e-01	-1.86e-01	6.50e-01
GO:0010592 positive regulation of lamellipodium assembly	10	3.09e-01	1.86e-01	6.91e-01
GO:0000792 heterochromatin	19	1.62e-01	-1.85e-01	5.10e-01
GO:0001968 fibronectin binding	10	3.12e-01	-1.85e-01	6.91e-01
GO:0000398 mRNA splicing, via spliceosome	87	2.94e-03	-1.85e-01	1.05e-01
GO:0034450 ubiquitin-ubiquitin ligase activity	12	2.69e-01	1.84e-01	6.52e-01
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment	35	5.90e-02	1.84e-01	3.44e-01
GO:0015026 coreceptor activity	13	2.50e-01	1.84e-01	6.27e-01
GO:0006865 amino acid transport	11	2.91e-01	1.84e-01	6.77e-01
GO:0007064 mitotic sister chromatid cohesion	10	3.14e-01	1.84e-01	6.92e-01
GO:0006298 mismatch repair	16	2.03e-01	1.84e-01	5.71e-01
GO:0019827 stem cell population maintenance	21	1.45e-01	-1.84e-01	4.80e-01
GO:0071300 cellular response to retinoic acid	17	1.90e-01	-1.84e-01	5.59e-01
GO:0099175 regulation of postsynapse organization	19	1.66e-01	1.83e-01	5.19e-01
GO:0140374 antiviral innate immune response	20	1.56e-01	-1.83e-01	5.01e-01
GO:0051131 chaperone-mediated protein complex assembly	14	2.35e-01	-1.83e-01	6.12e-01
GO:0140664 ATP-dependent DNA damage sensor activity	14	2.35e-01	1.83e-01	6.12e-01
GO:0035615 clathrin adaptor activity	10	3.16e-01	1.83e-01	6.94e-01
GO:0042626 ATPase-coupled transmembrane transporter activity	18	1.79e-01	1.83e-01	5.38e-01
GO:0004177 aminopeptidase activity	13	2.54e-01	-1.83e-01	6.33e-01
GO:0150052 regulation of postsynapse assembly	13	2.55e-01	-1.82e-01	6.35e-01
GO:0001558 regulation of cell growth	24	1.23e-01	-1.82e-01	4.55e-01
GO:0005385 zinc ion transmembrane transporter activity	15	2.23e-01	-1.82e-01	6.00e-01
GO:0010719 negative regulation of epithelial to mesenchymal transition	16	2.08e-01	-1.82e-01	5.81e-01
GO:0001530 lipopolysaccharide binding	12	2.77e-01	1.81e-01	6.60e-01
GO:0007166 cell surface receptor signaling pathway	40	4.73e-02	1.81e-01	3.19e-01
GO:0000786 nucleosome	16	2.10e-01	-1.81e-01	5.82e-01
GO:0071333 cellular response to glucose stimulus	12	2.78e-01	-1.81e-01	6.62e-01
GO:0008327 methyl-CpG binding	16	2.11e-01	-1.81e-01	5.82e-01
GO:0004713 protein tyrosine kinase activity	34	6.88e-02	-1.80e-01	3.62e-01
GO:0001657 ureteric bud development	14	2.45e-01	-1.80e-01	6.21e-01
GO:0070382 exocytic vesicle	10	3.26e-01	1.79e-01	6.99e-01
GO:0036211 protein modification process	16	2.14e-01	1.79e-01	5.88e-01
GO:0001786 phosphatidylserine binding	25	1.21e-01	1.79e-01	4.53e-01
GO:0008180 COP9 signalosome	21	1.56e-01	1.79e-01	5.02e-01
GO:0009792 embryo development ending in birth or egg hatching	10	3.29e-01	-1.78e-01	7.01e-01
GO:0001818 negative regulation of cytokine production	11	3.06e-01	1.78e-01	6.90e-01
GO:0060271 cilium assembly	126	5.64e-04	1.78e-01	4.00e-02
GO:0033962 P-body assembly	14	2.49e-01	-1.78e-01	6.27e-01
GO:0007097 nuclear migration	15	2.34e-01	1.78e-01	6.12e-01
GO:0001649 osteoblast differentiation	39	5.56e-02	-1.77e-01	3.37e-01
GO:0140588 chromatin looping	27	1.11e-01	-1.77e-01	4.41e-01
GO:0005721 pericentric heterochromatin	18	1.94e-01	-1.77e-01	5.61e-01
GO:0005879 axonemal microtubule	10	3.35e-01	1.76e-01	7.07e-01
GO:0017022 myosin binding	11	3.14e-01	-1.75e-01	6.92e-01
GO:0034198 cellular response to amino acid starvation	31	9.17e-02	1.75e-01	4.08e-01
GO:2000811 negative regulation of anoikis	10	3.38e-01	1.75e-01	7.08e-01
GO:0006897 endocytosis	92	3.83e-03	1.75e-01	1.25e-01
GO:0002088 lens development in camera-type eye	12	2.95e-01	-1.75e-01	6.80e-01
GO:0009791 post-embryonic development	36	7.04e-02	-1.74e-01	3.62e-01
GO:0000266 mitochondrial fission	10	3.40e-01	1.74e-01	7.09e-01
GO:0050905 neuromuscular process	10	3.40e-01	1.74e-01	7.09e-01
GO:0046716 muscle cell cellular homeostasis	15	2.43e-01	-1.74e-01	6.19e-01
GO:0009267 cellular response to starvation	48	3.70e-02	1.74e-01	2.90e-01
GO:0042474 middle ear morphogenesis	10	3.41e-01	1.74e-01	7.09e-01
GO:0006488 dolichol-linked oligosaccharide biosynthetic process	14	2.60e-01	1.74e-01	6.40e-01
GO:0001046 core promoter sequence-specific DNA binding	11	3.20e-01	-1.73e-01	6.95e-01
GO:0000228 nuclear chromosome	13	2.82e-01	-1.72e-01	6.66e-01
GO:0006396 RNA processing	21	1.72e-01	-1.72e-01	5.31e-01
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway	31	9.79e-02	1.72e-01	4.18e-01
GO:0008361 regulation of cell size	13	2.84e-01	1.72e-01	6.68e-01
GO:1905168 positive regulation of double-strand break repair via homologous recombination	25	1.38e-01	-1.71e-01	4.69e-01
GO:0005694 chromosome	76	9.86e-03	-1.71e-01	1.77e-01
GO:0005254 chloride channel activity	20	1.86e-01	1.71e-01	5.49e-01
GO:0035064 methylated histone binding	42	5.60e-02	-1.70e-01	3.37e-01
GO:0006635 fatty acid beta-oxidation	26	1.33e-01	1.70e-01	4.69e-01
GO:0045669 positive regulation of osteoblast differentiation	37	7.33e-02	-1.70e-01	3.62e-01
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT	11	3.29e-01	1.70e-01	7.01e-01
GO:0006338 chromatin remodeling	249	4.10e-06	-1.70e-01	1.21e-03
GO:0006099 tricarboxylic acid cycle	19	2.00e-01	1.70e-01	5.68e-01
GO:1990138 neuron projection extension	10	3.53e-01	1.70e-01	7.22e-01
GO:0005021 vascular endothelial growth factor receptor activity	15	2.55e-01	-1.70e-01	6.35e-01
GO:0048536 spleen development	23	1.59e-01	-1.70e-01	5.07e-01
GO:0001782 B cell homeostasis	12	3.11e-01	-1.69e-01	6.91e-01
GO:0005201 extracellular matrix structural constituent	12	3.11e-01	1.69e-01	6.91e-01
GO:0005930 axoneme	48	4.37e-02	1.68e-01	3.13e-01
GO:0045824 negative regulation of innate immune response	16	2.44e-01	-1.68e-01	6.19e-01
GO:0030136 clathrin-coated vesicle	29	1.17e-01	1.68e-01	4.50e-01
GO:0009410 response to xenobiotic stimulus	48	4.45e-02	-1.68e-01	3.14e-01
GO:0005764 lysosome	132	8.91e-04	1.68e-01	5.85e-02
GO:0070403 NAD+ binding	11	3.36e-01	1.68e-01	7.07e-01
GO:0006891 intra-Golgi vesicle-mediated transport	18	2.19e-01	1.67e-01	5.96e-01
GO:0032760 positive regulation of tumor necrosis factor production	32	1.02e-01	1.67e-01	4.22e-01
GO:0007265 Ras protein signal transduction	37	7.87e-02	-1.67e-01	3.75e-01
GO:0032420 stereocilium	14	2.79e-01	1.67e-01	6.62e-01
GO:0032720 negative regulation of tumor necrosis factor production	18	2.20e-01	-1.67e-01	5.96e-01
GO:0005179 hormone activity	13	2.99e-01	-1.66e-01	6.84e-01
GO:0007417 central nervous system development	41	6.55e-02	1.66e-01	3.60e-01
GO:0048477 oogenesis	14	2.84e-01	-1.65e-01	6.68e-01
GO:0032880 regulation of protein localization	41	6.72e-02	1.65e-01	3.62e-01
GO:0030182 neuron differentiation	56	3.28e-02	-1.65e-01	2.78e-01
GO:0030286 dynein complex	11	3.43e-01	1.65e-01	7.12e-01
GO:0042632 cholesterol homeostasis	39	7.47e-02	1.65e-01	3.64e-01
GO:0016491 oxidoreductase activity	47	5.12e-02	1.64e-01	3.33e-01
GO:0051879 Hsp90 protein binding	26	1.47e-01	1.64e-01	4.85e-01
GO:0007369 gastrulation	10	3.69e-01	-1.64e-01	7.31e-01
GO:0045214 sarcomere organization	13	3.06e-01	1.64e-01	6.90e-01
GO:0009636 response to toxic substance	15	2.72e-01	1.64e-01	6.54e-01
GO:0046488 phosphatidylinositol metabolic process	13	3.08e-01	-1.63e-01	6.90e-01
GO:0005540 hyaluronic acid binding	13	3.08e-01	1.63e-01	6.90e-01
GO:0007095 mitotic G2 DNA damage checkpoint signaling	30	1.22e-01	-1.63e-01	4.54e-01
GO:0072542 protein phosphatase activator activity	10	3.72e-01	1.63e-01	7.32e-01
GO:0071889 14-3-3 protein binding	15	2.75e-01	-1.63e-01	6.58e-01
GO:0001671 ATPase activator activity	18	2.33e-01	-1.62e-01	6.12e-01
GO:0019216 regulation of lipid metabolic process	10	3.74e-01	-1.62e-01	7.32e-01
GO:0008017 microtubule binding	153	5.46e-04	1.62e-01	4.00e-02
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway	13	3.12e-01	-1.62e-01	6.91e-01
GO:0007274 neuromuscular synaptic transmission	12	3.32e-01	1.62e-01	7.04e-01
GO:0072593 reactive oxygen species metabolic process	16	2.63e-01	1.62e-01	6.46e-01
GO:0003777 microtubule motor activity	23	1.80e-01	1.62e-01	5.38e-01
GO:0001222 transcription corepressor binding	27	1.47e-01	-1.61e-01	4.85e-01
GO:0099523 presynaptic cytosol	11	3.54e-01	1.61e-01	7.24e-01
GO:0002376 immune system process	12	3.34e-01	1.61e-01	7.06e-01
GO:0032040 small-subunit processome	59	3.25e-02	-1.61e-01	2.78e-01
GO:0030010 establishment of cell polarity	18	2.37e-01	1.61e-01	6.12e-01
GO:0003678 DNA helicase activity	20	2.14e-01	-1.61e-01	5.87e-01
GO:0030490 maturation of SSU-rRNA	12	3.36e-01	-1.61e-01	7.07e-01
GO:0001664 G protein-coupled receptor binding	21	2.03e-01	1.61e-01	5.71e-01
GO:0005581 collagen trimer	19	2.26e-01	1.60e-01	6.06e-01
GO:0060038 cardiac muscle cell proliferation	12	3.37e-01	1.60e-01	7.07e-01
GO:0098719 sodium ion import across plasma membrane	10	3.80e-01	-1.60e-01	7.38e-01
GO:0030175 filopodium	31	1.23e-01	1.60e-01	4.55e-01
GO:0031252 cell leading edge	18	2.40e-01	1.60e-01	6.16e-01
GO:0030133 transport vesicle	23	1.85e-01	1.60e-01	5.49e-01
GO:0050804 modulation of chemical synaptic transmission	35	1.04e-01	1.59e-01	4.28e-01
GO:0031573 mitotic intra-S DNA damage checkpoint signaling	11	3.62e-01	-1.59e-01	7.31e-01
GO:0045202 synapse	163	5.14e-04	1.58e-01	3.96e-02
GO:0120020 cholesterol transfer activity	12	3.45e-01	-1.57e-01	7.13e-01
GO:0070373 negative regulation of ERK1 and ERK2 cascade	30	1.36e-01	-1.57e-01	4.69e-01
GO:0033192 calmodulin-dependent protein phosphatase activity	16	2.77e-01	-1.57e-01	6.60e-01
GO:0001965 G-protein alpha-subunit binding	10	3.91e-01	1.57e-01	7.45e-01
GO:0032526 response to retinoic acid	15	2.94e-01	-1.57e-01	6.79e-01
GO:0005814 centriole	92	9.59e-03	1.56e-01	1.77e-01
GO:0031490 chromatin DNA binding	41	8.33e-02	-1.56e-01	3.85e-01
GO:0030097 hemopoiesis	25	1.77e-01	1.56e-01	5.35e-01
GO:0009954 proximal/distal pattern formation	14	3.13e-01	-1.56e-01	6.92e-01
GO:0005643 nuclear pore	33	1.22e-01	-1.56e-01	4.54e-01
GO:0003713 transcription coactivator activity	128	2.38e-03	-1.56e-01	9.59e-02
GO:0003824 catalytic activity	11	3.72e-01	1.56e-01	7.32e-01
GO:0048786 presynaptic active zone	10	3.94e-01	1.56e-01	7.45e-01
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	13	3.32e-01	1.55e-01	7.04e-01
GO:0002020 protease binding	44	7.49e-02	1.55e-01	3.64e-01
GO:0000149 SNARE binding	31	1.36e-01	1.55e-01	4.69e-01
GO:0001736 establishment of planar polarity	11	3.74e-01	1.55e-01	7.32e-01
GO:0071407 cellular response to organic cyclic compound	11	3.74e-01	-1.55e-01	7.32e-01
GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	35	1.14e-01	-1.55e-01	4.43e-01
GO:0071260 cellular response to mechanical stimulus	23	2.00e-01	1.54e-01	5.68e-01
GO:0061775 cohesin loader activity	24	1.93e-01	-1.54e-01	5.61e-01
GO:0032922 circadian regulation of gene expression	34	1.22e-01	-1.53e-01	4.54e-01
GO:0051260 protein homooligomerization	48	6.61e-02	-1.53e-01	3.60e-01
GO:0030018 Z disc	52	5.62e-02	-1.53e-01	3.37e-01
GO:0090314 positive regulation of protein targeting to membrane	12	3.60e-01	1.53e-01	7.28e-01
GO:0032008 positive regulation of TOR signaling	12	3.60e-01	1.53e-01	7.28e-01
GO:0003899 DNA-directed 5’-3’ RNA polymerase activity	10	4.05e-01	-1.52e-01	7.46e-01
GO:0003697 single-stranded DNA binding	67	3.13e-02	1.52e-01	2.75e-01
GO:0005802 trans-Golgi network	100	8.62e-03	1.52e-01	1.71e-01
GO:0032587 ruffle membrane	41	9.22e-02	1.52e-01	4.09e-01
GO:0045335 phagocytic vesicle	35	1.20e-01	1.52e-01	4.52e-01
GO:0071347 cellular response to interleukin-1	17	2.79e-01	1.52e-01	6.62e-01
GO:0030670 phagocytic vesicle membrane	19	2.52e-01	1.52e-01	6.30e-01
GO:0042098 T cell proliferation	16	2.94e-01	-1.52e-01	6.79e-01
GO:0000045 autophagosome assembly	52	5.89e-02	1.52e-01	3.44e-01
GO:0097060 synaptic membrane	12	3.64e-01	-1.51e-01	7.31e-01
GO:0070979 protein K11-linked ubiquitination	22	2.20e-01	-1.51e-01	5.96e-01
GO:0061749 forked DNA-dependent helicase activity	10	4.09e-01	-1.51e-01	7.50e-01
GO:0008168 methyltransferase activity	13	3.47e-01	-1.51e-01	7.16e-01
GO:0007043 cell-cell junction assembly	10	4.11e-01	1.50e-01	7.51e-01
GO:0048026 positive regulation of mRNA splicing, via spliceosome	12	3.68e-01	-1.50e-01	7.31e-01
GO:0060828 regulation of canonical Wnt signaling pathway	18	2.71e-01	-1.50e-01	6.54e-01
GO:0003676 nucleic acid binding	106	7.77e-03	-1.50e-01	1.63e-01
GO:0051781 positive regulation of cell division	13	3.50e-01	1.50e-01	7.19e-01
GO:0007266 Rho protein signal transduction	33	1.38e-01	1.49e-01	4.69e-01
GO:0016607 nuclear speck	241	6.82e-05	-1.49e-01	8.62e-03
GO:0031624 ubiquitin conjugating enzyme binding	17	2.87e-01	-1.49e-01	6.74e-01
GO:0097431 mitotic spindle pole	27	1.80e-01	-1.49e-01	5.38e-01
GO:0030897 HOPS complex	10	4.14e-01	-1.49e-01	7.55e-01
GO:0016581 NuRD complex	10	4.15e-01	-1.49e-01	7.55e-01
GO:0001508 action potential	11	3.93e-01	-1.49e-01	7.45e-01
GO:0060173 limb development	23	2.17e-01	-1.49e-01	5.94e-01
GO:0050750 low-density lipoprotein particle receptor binding	12	3.73e-01	-1.49e-01	7.32e-01
GO:0001223 transcription coactivator binding	22	2.28e-01	1.49e-01	6.08e-01
GO:0140584 chromatin extrusion motor activity	23	2.20e-01	-1.48e-01	5.96e-01
GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity	23	2.20e-01	-1.48e-01	5.96e-01
GO:0140849 ATP-dependent H2AZ histone chaperone activity	23	2.20e-01	-1.48e-01	5.96e-01
GO:0035924 cellular response to vascular endothelial growth factor stimulus	16	3.06e-01	1.48e-01	6.90e-01
GO:0031072 heat shock protein binding	26	1.93e-01	-1.48e-01	5.61e-01
GO:0061709 reticulophagy	15	3.23e-01	1.47e-01	6.98e-01
GO:0003774 cytoskeletal motor activity	13	3.57e-01	1.47e-01	7.27e-01
GO:0030168 platelet activation	11	3.98e-01	-1.47e-01	7.46e-01
GO:0007179 transforming growth factor beta receptor signaling pathway	49	7.53e-02	-1.47e-01	3.64e-01
GO:0006397 mRNA processing	72	3.12e-02	-1.47e-01	2.75e-01
GO:0042733 embryonic digit morphogenesis	29	1.71e-01	1.47e-01	5.29e-01
GO:0030509 BMP signaling pathway	37	1.22e-01	-1.47e-01	4.54e-01
GO:0042273 ribosomal large subunit biogenesis	22	2.34e-01	-1.47e-01	6.12e-01
GO:0003714 transcription corepressor activity	101	1.10e-02	-1.47e-01	1.79e-01
GO:0035987 endodermal cell differentiation	21	2.46e-01	1.46e-01	6.22e-01
GO:0071168 protein localization to chromatin	17	2.98e-01	1.46e-01	6.83e-01
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway	26	1.99e-01	1.46e-01	5.68e-01
GO:0071230 cellular response to amino acid stimulus	29	1.76e-01	1.45e-01	5.33e-01
GO:0080025 phosphatidylinositol-3,5-bisphosphate binding	15	3.32e-01	1.45e-01	7.04e-01
GO:0032467 positive regulation of cytokinesis	14	3.49e-01	1.45e-01	7.18e-01
GO:0045722 positive regulation of gluconeogenesis	11	4.07e-01	-1.44e-01	7.49e-01
GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels	16	3.18e-01	1.44e-01	6.95e-01
GO:0050681 nuclear androgen receptor binding	16	3.19e-01	-1.44e-01	6.95e-01
GO:0061024 membrane organization	13	3.70e-01	1.44e-01	7.32e-01
GO:0001221 transcription coregulator binding	17	3.05e-01	-1.44e-01	6.90e-01
GO:0070063 RNA polymerase binding	12	3.89e-01	1.44e-01	7.45e-01
GO:0030837 negative regulation of actin filament polymerization	14	3.53e-01	1.43e-01	7.22e-01
GO:0001578 microtubule bundle formation	15	3.37e-01	1.43e-01	7.07e-01
GO:0051402 neuron apoptotic process	42	1.10e-01	1.42e-01	4.40e-01
GO:0071466 cellular response to xenobiotic stimulus	24	2.28e-01	-1.42e-01	6.09e-01
GO:1990782 protein tyrosine kinase binding	14	3.57e-01	1.42e-01	7.27e-01
GO:0005978 glycogen biosynthetic process	11	4.15e-01	1.42e-01	7.55e-01
GO:0030334 regulation of cell migration	35	1.47e-01	1.42e-01	4.85e-01
GO:0048010 vascular endothelial growth factor receptor signaling pathway	13	3.78e-01	-1.41e-01	7.36e-01
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand	12	3.98e-01	-1.41e-01	7.46e-01
GO:0005769 early endosome	141	4.02e-03	1.41e-01	1.25e-01
GO:0003281 ventricular septum development	14	3.64e-01	-1.40e-01	7.31e-01
GO:0004181 metallocarboxypeptidase activity	13	3.82e-01	-1.40e-01	7.40e-01
GO:0032212 positive regulation of telomere maintenance via telomerase	16	3.33e-01	-1.40e-01	7.04e-01
GO:0010608 post-transcriptional regulation of gene expression	11	4.22e-01	-1.40e-01	7.59e-01
GO:0031669 cellular response to nutrient levels	13	3.83e-01	-1.40e-01	7.41e-01
GO:0048873 homeostasis of number of cells within a tissue	14	3.66e-01	1.40e-01	7.31e-01
GO:0005004 GPI-linked ephrin receptor activity	12	4.05e-01	-1.39e-01	7.46e-01
GO:0005011 macrophage colony-stimulating factor receptor activity	12	4.05e-01	-1.39e-01	7.46e-01
GO:0005018 platelet-derived growth factor alpha-receptor activity	12	4.05e-01	-1.39e-01	7.46e-01
GO:0005020 stem cell factor receptor activity	12	4.05e-01	-1.39e-01	7.46e-01
GO:0008288 boss receptor activity	12	4.05e-01	-1.39e-01	7.46e-01
GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway	12	4.05e-01	-1.39e-01	7.46e-01
GO:0036323 vascular endothelial growth factor receptor-1 signaling pathway	12	4.05e-01	-1.39e-01	7.46e-01
GO:0036332 placental growth factor receptor activity	12	4.05e-01	-1.39e-01	7.46e-01
GO:0038145 macrophage colony-stimulating factor signaling pathway	12	4.05e-01	-1.39e-01	7.46e-01
GO:0060175 brain-derived neurotrophic factor receptor activity	12	4.05e-01	-1.39e-01	7.46e-01
GO:0006955 immune response	41	1.24e-01	-1.39e-01	4.55e-01
GO:0001837 epithelial to mesenchymal transition	17	3.22e-01	1.39e-01	6.97e-01
GO:0046034 ATP metabolic process	13	3.87e-01	-1.39e-01	7.44e-01
GO:0001540 amyloid-beta binding	28	2.05e-01	1.39e-01	5.73e-01
GO:0060337 type I interferon-mediated signaling pathway	10	4.48e-01	-1.39e-01	7.75e-01
GO:0060324 face development	13	3.87e-01	-1.39e-01	7.44e-01
GO:0008584 male gonad development	27	2.13e-01	1.38e-01	5.87e-01
GO:0099149 regulation of postsynaptic neurotransmitter receptor internalization	13	3.90e-01	1.38e-01	7.45e-01
GO:0140297 DNA-binding transcription factor binding	72	4.35e-02	-1.38e-01	3.13e-01
GO:0040014 regulation of multicellular organism growth	12	4.10e-01	1.37e-01	7.51e-01
GO:0045766 positive regulation of angiogenesis	52	8.71e-02	1.37e-01	3.96e-01
GO:0101031 protein folding chaperone complex	18	3.14e-01	-1.37e-01	6.92e-01
GO:0019894 kinesin binding	21	2.77e-01	1.37e-01	6.60e-01
GO:0005112 Notch binding	13	3.93e-01	1.37e-01	7.45e-01
GO:0034704 calcium channel complex	11	4.32e-01	1.37e-01	7.67e-01
GO:0000086 G2/M transition of mitotic cell cycle	25	2.37e-01	1.37e-01	6.12e-01
GO:0035331 negative regulation of hippo signaling	18	3.16e-01	-1.37e-01	6.94e-01
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific	113	1.23e-02	-1.36e-01	1.85e-01
GO:0019915 lipid storage	11	4.33e-01	1.36e-01	7.67e-01
GO:0006334 nucleosome assembly	27	2.20e-01	-1.36e-01	5.96e-01
GO:0031167 rRNA methylation	11	4.34e-01	-1.36e-01	7.67e-01
GO:0006511 ubiquitin-dependent protein catabolic process	117	1.11e-02	-1.36e-01	1.79e-01
GO:0030054 cell junction	53	8.74e-02	-1.36e-01	3.97e-01
GO:0036464 cytoplasmic ribonucleoprotein granule	36	1.59e-01	1.36e-01	5.06e-01
GO:0060236 regulation of mitotic spindle organization	12	4.16e-01	1.36e-01	7.55e-01
GO:0005681 spliceosomal complex	43	1.24e-01	-1.36e-01	4.55e-01
GO:0051403 stress-activated MAPK cascade	12	4.17e-01	1.35e-01	7.57e-01
GO:0071363 cellular response to growth factor stimulus	19	3.09e-01	-1.35e-01	6.91e-01
GO:0048144 fibroblast proliferation	22	2.74e-01	1.35e-01	6.58e-01
GO:0001817 regulation of cytokine production	26	2.35e-01	-1.35e-01	6.12e-01
GO:0055038 recycling endosome membrane	43	1.27e-01	1.35e-01	4.56e-01
GO:0046907 intracellular transport	14	3.84e-01	1.34e-01	7.41e-01
GO:0002250 adaptive immune response	20	2.99e-01	1.34e-01	6.84e-01
GO:0019904 protein domain specific binding	103	1.89e-02	1.34e-01	2.25e-01
GO:0000082 G1/S transition of mitotic cell cycle	41	1.39e-01	1.34e-01	4.69e-01
GO:0005903 brush border	18	3.26e-01	1.34e-01	6.99e-01
GO:0008408 3’-5’ exonuclease activity	10	4.65e-01	-1.33e-01	7.86e-01
GO:0120163 negative regulation of cold-induced thermogenesis	21	2.91e-01	-1.33e-01	6.77e-01
GO:0005938 cell cortex	74	4.79e-02	1.33e-01	3.19e-01
GO:0098685 Schaffer collateral - CA1 synapse	43	1.33e-01	1.32e-01	4.69e-01
GO:0008333 endosome to lysosome transport	32	1.97e-01	1.32e-01	5.65e-01
GO:0031201 SNARE complex	33	1.91e-01	-1.32e-01	5.59e-01
GO:0070098 chemokine-mediated signaling pathway	10	4.72e-01	-1.31e-01	7.88e-01
GO:0051123 RNA polymerase II preinitiation complex assembly	16	3.64e-01	-1.31e-01	7.31e-01
GO:0042407 cristae formation	11	4.51e-01	1.31e-01	7.75e-01
GO:0016239 positive regulation of macroautophagy	17	3.50e-01	1.31e-01	7.19e-01
GO:0006094 gluconeogenesis	20	3.11e-01	1.31e-01	6.91e-01
GO:0006906 vesicle fusion	15	3.80e-01	1.31e-01	7.38e-01
GO:0016925 protein sumoylation	19	3.25e-01	-1.30e-01	6.99e-01
GO:0031901 early endosome membrane	75	5.09e-02	1.30e-01	3.33e-01
GO:0090734 site of DNA damage	22	2.90e-01	-1.30e-01	6.76e-01
GO:0031333 negative regulation of protein-containing complex assembly	16	3.69e-01	1.30e-01	7.31e-01
GO:0050729 positive regulation of inflammatory response	21	3.03e-01	1.30e-01	6.90e-01
GO:0071364 cellular response to epidermal growth factor stimulus	19	3.28e-01	1.30e-01	7.01e-01
GO:0090543 Flemming body	14	4.01e-01	1.30e-01	7.46e-01
GO:0048384 retinoic acid receptor signaling pathway	11	4.57e-01	-1.30e-01	7.79e-01
GO:0000781 chromosome, telomeric region	75	5.30e-02	-1.29e-01	3.33e-01
GO:0005874 microtubule	131	1.08e-02	1.29e-01	1.79e-01
GO:0048487 beta-tubulin binding	22	2.95e-01	1.29e-01	6.80e-01
GO:0005685 U1 snRNP	12	4.40e-01	-1.29e-01	7.72e-01
GO:0045746 negative regulation of Notch signaling pathway	16	3.73e-01	1.29e-01	7.32e-01
GO:0048704 embryonic skeletal system morphogenesis	18	3.45e-01	1.29e-01	7.13e-01
GO:0034605 cellular response to heat	16	3.75e-01	-1.28e-01	7.32e-01
GO:0046676 negative regulation of insulin secretion	10	4.84e-01	-1.28e-01	7.91e-01
GO:0043005 neuron projection	97	3.02e-02	1.27e-01	2.70e-01
GO:0045022 early endosome to late endosome transport	19	3.37e-01	1.27e-01	7.07e-01
GO:0098793 presynapse	64	7.85e-02	1.27e-01	3.75e-01
GO:0045862 positive regulation of proteolysis	12	4.46e-01	-1.27e-01	7.75e-01
GO:0030946 protein tyrosine phosphatase activity, metal-dependent	15	3.95e-01	-1.27e-01	7.45e-01
GO:0140793 histone H2AXY142 phosphatase activity	15	3.95e-01	-1.27e-01	7.45e-01
GO:0042393 histone binding	95	3.29e-02	-1.27e-01	2.78e-01
GO:0000922 spindle pole	69	6.89e-02	1.27e-01	3.62e-01
GO:0009566 fertilization	12	4.48e-01	1.27e-01	7.75e-01
GO:0071479 cellular response to ionizing radiation	22	3.05e-01	-1.26e-01	6.90e-01
GO:0016514 SWI/SNF complex	20	3.28e-01	-1.26e-01	7.01e-01
GO:0106222 lncRNA binding	17	3.67e-01	-1.26e-01	7.31e-01
GO:0005834 heterotrimeric G-protein complex	19	3.41e-01	1.26e-01	7.09e-01
GO:0035855 megakaryocyte development	10	4.90e-01	-1.26e-01	7.94e-01
GO:0031526 brush border membrane	12	4.50e-01	1.26e-01	7.75e-01
GO:0061025 membrane fusion	21	3.20e-01	-1.25e-01	6.95e-01
GO:0004402 histone acetyltransferase activity	11	4.72e-01	-1.25e-01	7.88e-01
GO:0005765 lysosomal membrane	137	1.17e-02	1.25e-01	1.79e-01
GO:0016605 PML body	61	9.32e-02	-1.24e-01	4.10e-01
GO:1990830 cellular response to leukemia inhibitory factor	67	7.93e-02	-1.24e-01	3.76e-01
GO:0005929 cilium	78	5.95e-02	1.24e-01	3.44e-01
GO:0000151 ubiquitin ligase complex	48	1.40e-01	-1.23e-01	4.71e-01
GO:0051457 maintenance of protein location in nucleus	10	5.00e-01	-1.23e-01	8.04e-01
GO:0045995 regulation of embryonic development	27	2.69e-01	-1.23e-01	6.52e-01
GO:0003723 RNA binding	372	5.00e-05	-1.23e-01	8.05e-03
GO:0032868 response to insulin	22	3.19e-01	-1.23e-01	6.95e-01
GO:0007059 chromosome segregation	41	1.74e-01	1.23e-01	5.32e-01
GO:0035176 social behavior	16	3.96e-01	1.23e-01	7.45e-01
GO:0042391 regulation of membrane potential	13	4.44e-01	-1.23e-01	7.75e-01
GO:0005516 calmodulin binding	68	8.18e-02	1.22e-01	3.81e-01
GO:0005164 tumor necrosis factor receptor binding	13	4.46e-01	-1.22e-01	7.75e-01
GO:0016282 eukaryotic 43S preinitiation complex	14	4.31e-01	1.22e-01	7.67e-01
GO:0031410 cytoplasmic vesicle	107	3.00e-02	1.22e-01	2.70e-01
GO:0048812 neuron projection morphogenesis	30	2.50e-01	-1.21e-01	6.27e-01
GO:0061136 regulation of proteasomal protein catabolic process	11	4.86e-01	1.21e-01	7.91e-01
GO:0001778 plasma membrane repair	16	4.01e-01	1.21e-01	7.46e-01
GO:0001570 vasculogenesis	27	2.79e-01	-1.21e-01	6.62e-01
GO:1903078 positive regulation of protein localization to plasma membrane	21	3.40e-01	1.20e-01	7.09e-01
GO:0030140 trans-Golgi network transport vesicle	11	4.91e-01	-1.20e-01	7.94e-01
GO:0005884 actin filament	43	1.74e-01	1.20e-01	5.32e-01
GO:0071944 cell periphery	12	4.73e-01	1.20e-01	7.88e-01
GO:0030672 synaptic vesicle membrane	44	1.70e-01	1.20e-01	5.27e-01
GO:0035791 platelet-derived growth factor receptor-beta signaling pathway	15	4.23e-01	-1.19e-01	7.60e-01
GO:0034332 adherens junction organization	13	4.56e-01	1.19e-01	7.78e-01
GO:0005109 frizzled binding	17	3.95e-01	-1.19e-01	7.45e-01
GO:0006325 chromatin organization	66	9.40e-02	-1.19e-01	4.10e-01
GO:0043122 regulation of canonical NF-kappaB signal transduction	17	3.95e-01	1.19e-01	7.45e-01
GO:0031290 retinal ganglion cell axon guidance	11	4.95e-01	-1.19e-01	7.98e-01
GO:0005813 centrosome	345	1.56e-04	1.19e-01	1.63e-02
GO:1902894 negative regulation of miRNA transcription	12	4.76e-01	-1.19e-01	7.88e-01
GO:0048854 brain morphogenesis	14	4.42e-01	1.19e-01	7.73e-01
GO:0086091 regulation of heart rate by cardiac conduction	18	3.84e-01	-1.19e-01	7.41e-01
GO:0050770 regulation of axonogenesis	13	4.60e-01	-1.18e-01	7.81e-01
GO:0009060 aerobic respiration	10	5.18e-01	1.18e-01	8.19e-01
GO:0070161 anchoring junction	17	4.01e-01	-1.18e-01	7.46e-01
GO:0060976 coronary vasculature development	18	3.88e-01	-1.18e-01	7.44e-01
GO:0000226 microtubule cytoskeleton organization	69	9.16e-02	1.18e-01	4.08e-01
GO:1990904 ribonucleoprotein complex	104	3.97e-02	1.17e-01	2.99e-01
GO:0005509 calcium ion binding	264	1.16e-03	1.17e-01	6.76e-02
GO:1902476 chloride transmembrane transport	40	2.03e-01	1.16e-01	5.71e-01
GO:0071456 cellular response to hypoxia	34	2.40e-01	1.16e-01	6.16e-01
GO:0030488 tRNA methylation	20	3.68e-01	-1.16e-01	7.31e-01
GO:0017116 single-stranded DNA helicase activity	16	4.21e-01	1.16e-01	7.59e-01
GO:0000176 nuclear exosome (RNase complex)	12	4.86e-01	-1.16e-01	7.91e-01
GO:0006457 protein folding	81	7.43e-02	-1.15e-01	3.62e-01
GO:0032418 lysosome localization	23	3.41e-01	-1.15e-01	7.09e-01
GO:0005730 nucleolus	441	4.01e-05	-1.15e-01	7.11e-03
GO:0007628 adult walking behavior	13	4.74e-01	-1.15e-01	7.88e-01
GO:0045765 regulation of angiogenesis	11	5.11e-01	1.15e-01	8.14e-01
GO:0034446 substrate adhesion-dependent cell spreading	35	2.41e-01	-1.15e-01	6.16e-01
GO:0030332 cyclin binding	20	3.76e-01	1.14e-01	7.33e-01
GO:0001756 somitogenesis	24	3.32e-01	-1.14e-01	7.04e-01
GO:0048870 cell motility	11	5.12e-01	1.14e-01	8.14e-01
GO:0005762 mitochondrial large ribosomal subunit	38	2.23e-01	-1.14e-01	6.00e-01
GO:0051560 mitochondrial calcium ion homeostasis	13	4.76e-01	-1.14e-01	7.88e-01
GO:0032743 positive regulation of interleukin-2 production	16	4.30e-01	1.14e-01	7.67e-01
GO:0038062 protein tyrosine kinase collagen receptor activity	13	4.77e-01	-1.14e-01	7.88e-01
GO:0006886 intracellular protein transport	159	1.36e-02	1.14e-01	1.94e-01
GO:0007094 mitotic spindle assembly checkpoint signaling	19	3.91e-01	1.14e-01	7.45e-01
GO:0005125 cytokine activity	27	3.07e-01	-1.14e-01	6.90e-01
GO:0098686 hippocampal mossy fiber to CA3 synapse	18	4.06e-01	-1.13e-01	7.47e-01
GO:0005019 platelet-derived growth factor beta-receptor activity	13	4.80e-01	-1.13e-01	7.91e-01
GO:0090090 negative regulation of canonical Wnt signaling pathway	70	1.03e-01	-1.13e-01	4.23e-01
GO:0001937 negative regulation of endothelial cell proliferation	12	4.98e-01	-1.13e-01	8.01e-01
GO:0007528 neuromuscular junction development	15	4.49e-01	1.13e-01	7.75e-01
GO:0005686 U2 snRNP	16	4.34e-01	-1.13e-01	7.67e-01
GO:0003700 DNA-binding transcription factor activity	79	8.35e-02	-1.13e-01	3.85e-01
GO:0008154 actin polymerization or depolymerization	11	5.18e-01	1.13e-01	8.19e-01
GO:0098794 postsynapse	65	1.17e-01	1.13e-01	4.49e-01
GO:0003924 GTPase activity	175	1.06e-02	1.12e-01	1.79e-01
GO:0005200 structural constituent of cytoskeleton	27	3.14e-01	1.12e-01	6.92e-01
GO:0005977 glycogen metabolic process	13	4.84e-01	1.12e-01	7.91e-01
GO:0048821 erythrocyte development	15	4.53e-01	-1.12e-01	7.76e-01
GO:0006493 protein O-linked glycosylation	31	2.81e-01	-1.12e-01	6.64e-01
GO:0001726 ruffle	43	2.06e-01	1.11e-01	5.75e-01
GO:0090307 mitotic spindle assembly	30	2.92e-01	-1.11e-01	6.77e-01
GO:0072089 stem cell proliferation	22	3.67e-01	1.11e-01	7.31e-01
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway	43	2.09e-01	1.11e-01	5.81e-01
GO:0000124 SAGA complex	15	4.58e-01	-1.11e-01	7.80e-01
GO:0070050 neuron cellular homeostasis	14	4.74e-01	-1.11e-01	7.88e-01
GO:0016192 vesicle-mediated transport	101	5.64e-02	1.10e-01	3.37e-01
GO:0005637 nuclear inner membrane	24	3.52e-01	1.10e-01	7.21e-01
GO:0051497 negative regulation of stress fiber assembly	18	4.20e-01	1.10e-01	7.59e-01
GO:0048787 presynaptic active zone membrane	10	5.48e-01	1.10e-01	8.33e-01
GO:0007098 centrosome cycle	17	4.34e-01	1.10e-01	7.67e-01
GO:0098655 monoatomic cation transmembrane transport	14	4.78e-01	1.09e-01	7.90e-01
GO:0019901 protein kinase binding	235	3.98e-03	1.09e-01	1.25e-01
GO:0030496 midbody	99	6.05e-02	1.09e-01	3.47e-01
GO:0042307 positive regulation of protein import into nucleus	25	3.45e-01	-1.09e-01	7.13e-01
GO:0042274 ribosomal small subunit biogenesis	44	2.11e-01	-1.09e-01	5.82e-01
GO:0045732 positive regulation of protein catabolic process	46	2.02e-01	1.09e-01	5.71e-01
GO:0035035 histone acetyltransferase binding	12	5.14e-01	-1.09e-01	8.16e-01
GO:0044389 ubiquitin-like protein ligase binding	16	4.52e-01	-1.09e-01	7.75e-01
GO:0007596 blood coagulation	26	3.38e-01	1.09e-01	7.08e-01
GO:0035567 non-canonical Wnt signaling pathway	14	4.82e-01	-1.08e-01	7.91e-01
GO:0005507 copper ion binding	23	3.69e-01	-1.08e-01	7.31e-01
GO:0098609 cell-cell adhesion	82	9.07e-02	-1.08e-01	4.07e-01
GO:0043679 axon terminus	17	4.40e-01	-1.08e-01	7.72e-01
GO:0000146 microfilament motor activity	19	4.15e-01	-1.08e-01	7.55e-01
GO:0016525 negative regulation of angiogenesis	35	2.69e-01	-1.08e-01	6.52e-01
GO:0044325 transmembrane transporter binding	58	1.57e-01	1.08e-01	5.02e-01
GO:0003688 DNA replication origin binding	12	5.21e-01	1.07e-01	8.20e-01
GO:0061436 establishment of skin barrier	13	5.04e-01	-1.07e-01	8.07e-01
GO:0000407 phagophore assembly site	20	4.08e-01	1.07e-01	7.50e-01
GO:0005096 GTPase activator activity	152	2.34e-02	1.07e-01	2.52e-01
GO:0015297 antiporter activity	18	4.34e-01	1.07e-01	7.67e-01
GO:0050853 B cell receptor signaling pathway	19	4.21e-01	1.07e-01	7.59e-01
GO:0008283 cell population proliferation	66	1.35e-01	-1.07e-01	4.69e-01
GO:0038109 Kit signaling pathway	14	4.92e-01	-1.06e-01	7.95e-01
GO:0019838 growth factor binding	11	5.43e-01	-1.06e-01	8.31e-01
GO:0009617 response to bacterium	37	2.67e-01	1.06e-01	6.51e-01
GO:0009887 animal organ morphogenesis	34	2.89e-01	1.05e-01	6.75e-01
GO:0070527 platelet aggregation	16	4.67e-01	1.05e-01	7.86e-01
GO:0006914 autophagy	43	2.34e-01	1.05e-01	6.12e-01
GO:0004198 calcium-dependent cysteine-type endopeptidase activity	10	5.67e-01	1.05e-01	8.44e-01
GO:0004864 protein phosphatase inhibitor activity	13	5.14e-01	-1.05e-01	8.16e-01
GO:0061157 mRNA destabilization	12	5.31e-01	-1.05e-01	8.27e-01
GO:0015485 cholesterol binding	29	3.32e-01	1.04e-01	7.04e-01
GO:0007040 lysosome organization	33	3.02e-01	-1.04e-01	6.89e-01
GO:0048741 skeletal muscle fiber development	16	4.72e-01	1.04e-01	7.88e-01
GO:0071320 cellular response to cAMP	18	4.46e-01	1.04e-01	7.75e-01
GO:0001666 response to hypoxia	52	1.96e-01	-1.04e-01	5.65e-01
GO:0030198 extracellular matrix organization	75	1.22e-01	1.04e-01	4.54e-01
GO:0006882 intracellular zinc ion homeostasis	13	5.18e-01	1.03e-01	8.19e-01
GO:0097546 ciliary base	17	4.61e-01	1.03e-01	7.81e-01
GO:0008053 mitochondrial fusion	17	4.61e-01	-1.03e-01	7.81e-01
GO:0071011 precatalytic spliceosome	12	5.36e-01	1.03e-01	8.30e-01
GO:0072686 mitotic spindle	69	1.40e-01	1.03e-01	4.71e-01
GO:0030234 enzyme regulator activity	14	5.08e-01	1.02e-01	8.12e-01
GO:0061077 chaperone-mediated protein folding	16	4.80e-01	-1.02e-01	7.91e-01
GO:0050766 positive regulation of phagocytosis	14	5.09e-01	-1.02e-01	8.12e-01
GO:0006486 protein glycosylation	45	2.37e-01	-1.02e-01	6.12e-01
GO:0004435 phosphatidylinositol phospholipase C activity	12	5.41e-01	1.02e-01	8.31e-01
GO:0032731 positive regulation of interleukin-1 beta production	11	5.59e-01	-1.02e-01	8.42e-01
GO:0034097 response to cytokine	12	5.42e-01	-1.02e-01	8.31e-01
GO:0033077 T cell differentiation in thymus	18	4.56e-01	1.01e-01	7.78e-01
GO:0007131 reciprocal meiotic recombination	12	5.44e-01	1.01e-01	8.31e-01
GO:0006909 phagocytosis	23	4.02e-01	1.01e-01	7.46e-01
GO:0006869 lipid transport	28	3.55e-01	1.01e-01	7.25e-01
GO:0030073 insulin secretion	13	5.29e-01	-1.01e-01	8.26e-01
GO:0032981 mitochondrial respiratory chain complex I assembly	38	2.84e-01	1.01e-01	6.68e-01
GO:0098839 postsynaptic density membrane	35	3.04e-01	1.00e-01	6.90e-01
GO:0071782 endoplasmic reticulum tubular network	12	5.47e-01	-1.00e-01	8.33e-01
GO:2000300 regulation of synaptic vesicle exocytosis	19	4.49e-01	1.00e-01	7.75e-01
GO:0007605 sensory perception of sound	55	1.99e-01	1.00e-01	5.68e-01
GO:0006302 double-strand break repair	45	2.46e-01	-1.00e-01	6.22e-01
GO:0035115 embryonic forelimb morphogenesis	16	4.89e-01	9.98e-02	7.94e-01
GO:0008217 regulation of blood pressure	19	4.52e-01	9.98e-02	7.75e-01
GO:0010008 endosome membrane	86	1.10e-01	9.98e-02	4.40e-01
GO:0048278 vesicle docking	13	5.34e-01	9.97e-02	8.29e-01
GO:0050680 negative regulation of epithelial cell proliferation	24	3.98e-01	-9.96e-02	7.46e-01
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway	11	5.68e-01	-9.96e-02	8.44e-01
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	12	5.51e-01	9.95e-02	8.35e-01
GO:0048511 rhythmic process	25	3.90e-01	9.93e-02	7.45e-01
GO:0019955 cytokine binding	13	5.36e-01	-9.92e-02	8.30e-01
GO:0046329 negative regulation of JNK cascade	12	5.53e-01	9.90e-02	8.37e-01
GO:0007411 axon guidance	79	1.29e-01	-9.89e-02	4.61e-01
GO:0019882 antigen processing and presentation	11	5.71e-01	9.88e-02	8.46e-01
GO:0035091 phosphatidylinositol binding	74	1.42e-01	9.88e-02	4.76e-01
GO:0042100 B cell proliferation	14	5.24e-01	-9.84e-02	8.21e-01
GO:0060021 roof of mouth development	35	3.14e-01	-9.83e-02	6.92e-01
GO:0006654 phosphatidic acid biosynthetic process	12	5.56e-01	9.83e-02	8.39e-01
GO:0045893 positive regulation of DNA-templated transcription	225	1.14e-02	-9.81e-02	1.79e-01
GO:0140311 protein sequestering activity	18	4.72e-01	9.80e-02	7.88e-01
GO:0071806 protein transmembrane transport	12	5.57e-01	-9.79e-02	8.40e-01
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process	19	4.61e-01	9.78e-02	7.81e-01
GO:0000785 chromatin	242	8.99e-03	-9.78e-02	1.71e-01
GO:0032496 response to lipopolysaccharide	37	3.04e-01	9.76e-02	6.90e-01
GO:0060326 cell chemotaxis	27	3.80e-01	-9.76e-02	7.38e-01
GO:0031594 neuromuscular junction	34	3.25e-01	9.76e-02	6.99e-01
GO:0000209 protein polyubiquitination	78	1.37e-01	-9.75e-02	4.69e-01
GO:0035401 histone H3Y41 kinase activity	21	4.39e-01	-9.75e-02	7.72e-01
GO:0030134 COPII-coated ER to Golgi transport vesicle	21	4.40e-01	9.74e-02	7.72e-01
GO:0014069 postsynaptic density	98	9.62e-02	9.74e-02	4.15e-01
GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity	13	5.44e-01	-9.72e-02	8.31e-01
GO:0030163 protein catabolic process	30	3.57e-01	9.71e-02	7.27e-01
GO:0031547 brain-derived neurotrophic factor receptor signaling pathway	14	5.30e-01	-9.70e-02	8.26e-01
GO:0010494 cytoplasmic stress granule	58	2.02e-01	-9.70e-02	5.71e-01
GO:0000932 P-body	61	1.91e-01	-9.70e-02	5.59e-01
GO:0043588 skin development	24	4.11e-01	-9.69e-02	7.51e-01
GO:0006605 protein targeting	18	4.77e-01	9.69e-02	7.88e-01
GO:2000737 negative regulation of stem cell differentiation	12	5.61e-01	-9.69e-02	8.42e-01
GO:0032007 negative regulation of TOR signaling	19	4.65e-01	9.68e-02	7.86e-01
GO:0006487 protein N-linked glycosylation	30	3.60e-01	9.67e-02	7.28e-01
GO:0007080 mitotic metaphase chromosome alignment	23	4.24e-01	9.64e-02	7.60e-01
GO:0010595 positive regulation of endothelial cell migration	26	3.95e-01	9.64e-02	7.45e-01
GO:0043923 positive regulation by host of viral transcription	12	5.64e-01	9.63e-02	8.43e-01
GO:0003727 single-stranded RNA binding	21	4.45e-01	-9.62e-02	7.75e-01
GO:0032715 negative regulation of interleukin-6 production	14	5.33e-01	-9.62e-02	8.29e-01
GO:0010842 retina layer formation	12	5.64e-01	-9.61e-02	8.43e-01
GO:0035025 positive regulation of Rho protein signal transduction	10	5.99e-01	-9.60e-02	8.65e-01
GO:0005515 protein binding	91	1.15e-01	-9.58e-02	4.43e-01
GO:0070085 glycosylation	14	5.36e-01	-9.56e-02	8.30e-01
GO:0006275 regulation of DNA replication	24	4.19e-01	-9.54e-02	7.58e-01
GO:0030878 thyroid gland development	14	5.37e-01	-9.53e-02	8.31e-01
GO:0000794 condensed nuclear chromosome	20	4.64e-01	9.45e-02	7.85e-01
GO:0051721 protein phosphatase 2A binding	14	5.41e-01	-9.43e-02	8.31e-01
GO:0005876 spindle microtubule	20	4.67e-01	9.40e-02	7.86e-01
GO:0003341 cilium movement	10	6.07e-01	9.40e-02	8.69e-01
GO:0006281 DNA repair	95	1.15e-01	-9.38e-02	4.43e-01
GO:0000712 resolution of meiotic recombination intermediates	14	5.44e-01	9.37e-02	8.31e-01
GO:0006357 regulation of transcription by RNA polymerase II	549	1.94e-04	-9.36e-02	1.91e-02
GO:0043408 regulation of MAPK cascade	21	4.58e-01	-9.35e-02	7.80e-01
GO:0008654 phospholipid biosynthetic process	12	5.75e-01	-9.35e-02	8.49e-01
GO:0031369 translation initiation factor binding	12	5.76e-01	-9.33e-02	8.49e-01
GO:0008013 beta-catenin binding	47	2.69e-01	9.32e-02	6.52e-01
GO:0010976 positive regulation of neuron projection development	30	3.77e-01	9.32e-02	7.35e-01
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway	19	4.82e-01	-9.31e-02	7.91e-01
GO:0050885 neuromuscular process controlling balance	24	4.30e-01	-9.30e-02	7.67e-01
GO:0004386 helicase activity	40	3.09e-01	-9.30e-02	6.91e-01
GO:0051726 regulation of cell cycle	104	1.02e-01	-9.29e-02	4.22e-01
GO:0003682 chromatin binding	239	1.37e-02	-9.28e-02	1.94e-01
GO:0012507 ER to Golgi transport vesicle membrane	11	5.94e-01	9.27e-02	8.62e-01
GO:0140801 histone H2AXY142 kinase activity	22	4.53e-01	-9.24e-02	7.76e-01
GO:0038066 p38MAPK cascade	11	5.96e-01	9.24e-02	8.62e-01
GO:0050839 cell adhesion molecule binding	20	4.76e-01	-9.21e-02	7.88e-01
GO:0006783 heme biosynthetic process	10	6.14e-01	9.20e-02	8.73e-01
GO:0034244 negative regulation of transcription elongation by RNA polymerase II	13	5.67e-01	9.18e-02	8.44e-01
GO:0044183 protein folding chaperone	21	4.67e-01	-9.17e-02	7.86e-01
GO:0061630 ubiquitin protein ligase activity	177	3.60e-02	-9.16e-02	2.89e-01
GO:0035082 axoneme assembly	10	6.17e-01	9.13e-02	8.76e-01
GO:0009986 cell surface	182	3.44e-02	9.11e-02	2.87e-01
GO:1900182 positive regulation of protein localization to nucleus	25	4.32e-01	-9.08e-02	7.67e-01
GO:0007517 muscle organ development	12	5.88e-01	9.02e-02	8.59e-01
GO:0034067 protein localization to Golgi apparatus	13	5.73e-01	9.02e-02	8.48e-01
GO:0048008 platelet-derived growth factor receptor signaling pathway	17	5.20e-01	-9.02e-02	8.20e-01
GO:0051649 establishment of localization in cell	40	3.25e-01	9.00e-02	6.99e-01
GO:0001654 eye development	17	5.21e-01	-9.00e-02	8.20e-01
GO:0005776 autophagosome	41	3.19e-01	8.99e-02	6.95e-01
GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process	14	5.61e-01	8.98e-02	8.42e-01
GO:0030864 cortical actin cytoskeleton	33	3.72e-01	8.98e-02	7.32e-01
GO:0002062 chondrocyte differentiation	22	4.68e-01	8.95e-02	7.86e-01
GO:0004252 serine-type endopeptidase activity	50	2.74e-01	8.94e-02	6.58e-01
GO:0016459 myosin complex	24	4.49e-01	-8.93e-02	7.75e-01
GO:0004519 endonuclease activity	14	5.64e-01	-8.90e-02	8.43e-01
GO:0051020 GTPase binding	15	5.51e-01	-8.88e-02	8.35e-01
GO:0016477 cell migration	136	7.42e-02	8.88e-02	3.62e-01
GO:0051496 positive regulation of stress fiber assembly	31	3.94e-01	-8.85e-02	7.45e-01
GO:0043113 receptor clustering	12	5.96e-01	8.84e-02	8.62e-01
GO:0043197 dendritic spine	46	3.00e-01	8.83e-02	6.86e-01
GO:0060090 molecular adaptor activity	75	1.86e-01	8.83e-02	5.50e-01
GO:0000460 maturation of 5.8S rRNA	11	6.14e-01	8.79e-02	8.73e-01
GO:0009611 response to wounding	19	5.09e-01	-8.75e-02	8.12e-01
GO:0060339 negative regulation of type I interferon-mediated signaling pathway	13	5.86e-01	-8.72e-02	8.57e-01
GO:0030424 axon	119	1.01e-01	-8.71e-02	4.21e-01
GO:0045747 positive regulation of Notch signaling pathway	23	4.70e-01	8.71e-02	7.88e-01
GO:0042789 mRNA transcription by RNA polymerase II	27	4.34e-01	-8.70e-02	7.67e-01
GO:0070588 calcium ion transmembrane transport	46	3.08e-01	8.69e-02	6.90e-01
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane	18	5.24e-01	8.68e-02	8.21e-01
GO:0034614 cellular response to reactive oxygen species	16	5.48e-01	-8.68e-02	8.33e-01
GO:0001938 positive regulation of endothelial cell proliferation	22	4.83e-01	8.65e-02	7.91e-01
GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity	10	6.37e-01	8.61e-02	8.93e-01
GO:0042383 sarcolemma	37	3.66e-01	8.59e-02	7.31e-01
GO:0006974 DNA damage response	120	1.06e-01	-8.55e-02	4.33e-01
GO:0007288 sperm axoneme assembly	17	5.45e-01	8.47e-02	8.32e-01
GO:0031593 polyubiquitin modification-dependent protein binding	19	5.24e-01	-8.45e-02	8.21e-01
GO:0098982 GABA-ergic synapse	31	4.16e-01	8.44e-02	7.55e-01
GO:0048471 perinuclear region of cytoplasm	288	1.41e-02	8.44e-02	1.96e-01
GO:0008201 heparin binding	57	2.72e-01	8.42e-02	6.54e-01
GO:0014032 neural crest cell development	11	6.29e-01	8.42e-02	8.85e-01
GO:0030534 adult behavior	10	6.45e-01	8.41e-02	8.95e-01
GO:1904115 axon cytoplasm	25	4.71e-01	8.33e-02	7.88e-01
GO:0001658 branching involved in ureteric bud morphogenesis	18	5.41e-01	8.33e-02	8.31e-01
GO:0072344 rescue of stalled ribosome	26	4.64e-01	-8.30e-02	7.85e-01
GO:0009306 protein secretion	20	5.21e-01	8.29e-02	8.20e-01
GO:0005669 transcription factor TFIID complex	22	5.02e-01	-8.28e-02	8.05e-01
GO:0070301 cellular response to hydrogen peroxide	24	4.84e-01	-8.26e-02	7.91e-01
GO:0000976 transcription cis-regulatory region binding	55	2.92e-01	-8.22e-02	6.77e-01
GO:0000723 telomere maintenance	29	4.44e-01	-8.21e-02	7.75e-01
GO:0017053 transcription repressor complex	34	4.09e-01	-8.18e-02	7.50e-01
GO:0042277 peptide binding	10	6.54e-01	-8.18e-02	8.96e-01
GO:0099170 postsynaptic modulation of chemical synaptic transmission	12	6.24e-01	-8.17e-02	8.81e-01
GO:0051087 protein-folding chaperone binding	56	2.91e-01	-8.16e-02	6.77e-01
GO:0097191 extrinsic apoptotic signaling pathway	20	5.28e-01	8.16e-02	8.26e-01
GO:0007005 mitochondrion organization	62	2.67e-01	8.15e-02	6.52e-01
GO:0045666 positive regulation of neuron differentiation	26	4.72e-01	8.15e-02	7.88e-01
GO:0003712 transcription coregulator activity	76	2.21e-01	-8.13e-02	5.96e-01
GO:0060070 canonical Wnt signaling pathway	58	2.88e-01	-8.08e-02	6.74e-01
GO:0035329 hippo signaling	18	5.53e-01	8.07e-02	8.37e-01
GO:0022008 neurogenesis	31	4.38e-01	-8.06e-02	7.71e-01
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	11	6.44e-01	-8.06e-02	8.94e-01
GO:0072657 protein localization to membrane	19	5.44e-01	-8.05e-02	8.31e-01
GO:0038023 signaling receptor activity	41	3.74e-01	8.02e-02	7.32e-01
GO:0016363 nuclear matrix	46	3.47e-01	-8.02e-02	7.16e-01
GO:0005856 cytoskeleton	174	6.86e-02	8.02e-02	3.62e-01
GO:0000791 euchromatin	29	4.56e-01	-8.00e-02	7.78e-01
GO:0006887 exocytosis	44	3.59e-01	-8.00e-02	7.28e-01
GO:0071222 cellular response to lipopolysaccharide	44	3.60e-01	7.98e-02	7.28e-01
GO:0000287 magnesium ion binding	150	9.25e-02	7.97e-02	4.10e-01
GO:0071805 potassium ion transmembrane transport	39	3.89e-01	7.97e-02	7.45e-01
GO:0008143 poly(A) binding	13	6.19e-01	7.97e-02	8.78e-01
GO:0019899 enzyme binding	111	1.48e-01	7.96e-02	4.86e-01
GO:0031116 positive regulation of microtubule polymerization	11	6.48e-01	7.96e-02	8.96e-01
GO:0006268 DNA unwinding involved in DNA replication	14	6.07e-01	7.94e-02	8.69e-01
GO:0004857 enzyme inhibitor activity	12	6.36e-01	-7.90e-02	8.92e-01
GO:0031012 extracellular matrix	90	1.99e-01	-7.84e-02	5.68e-01
GO:0007626 locomotory behavior	27	4.81e-01	-7.83e-02	7.91e-01
GO:0045453 bone resorption	11	6.53e-01	-7.83e-02	8.96e-01
GO:0005484 SNAP receptor activity	26	4.90e-01	-7.82e-02	7.94e-01
GO:0042826 histone deacetylase binding	66	2.75e-01	-7.77e-02	6.59e-01
GO:0004867 serine-type endopeptidase inhibitor activity	22	5.29e-01	-7.76e-02	8.26e-01
GO:0005788 endoplasmic reticulum lumen	40	3.97e-01	-7.74e-02	7.46e-01
GO:0042327 positive regulation of phosphorylation	12	6.43e-01	7.73e-02	8.94e-01
GO:0061484 hematopoietic stem cell homeostasis	12	6.43e-01	-7.72e-02	8.94e-01
GO:0048012 hepatocyte growth factor receptor signaling pathway	17	5.84e-01	-7.68e-02	8.54e-01
GO:0060382 regulation of DNA strand elongation	10	6.74e-01	-7.67e-02	8.99e-01
GO:0046983 protein dimerization activity	70	2.68e-01	-7.67e-02	6.52e-01
GO:0070830 bicellular tight junction assembly	19	5.64e-01	7.65e-02	8.43e-01
GO:0015459 potassium channel regulator activity	14	6.21e-01	-7.63e-02	8.78e-01
GO:0004896 cytokine receptor activity	20	5.55e-01	7.62e-02	8.39e-01
GO:0016328 lateral plasma membrane	24	5.18e-01	-7.62e-02	8.19e-01
GO:0000139 Golgi membrane	262	3.47e-02	7.60e-02	2.87e-01
GO:0042981 regulation of apoptotic process	55	3.31e-01	-7.58e-02	7.04e-01
GO:0035725 sodium ion transmembrane transport	46	3.74e-01	7.58e-02	7.32e-01
GO:0005604 basement membrane	42	3.96e-01	-7.58e-02	7.45e-01
GO:0016922 nuclear receptor binding	21	5.48e-01	7.57e-02	8.33e-01
GO:0032588 trans-Golgi network membrane	27	4.97e-01	-7.56e-02	7.99e-01
GO:0033173 calcineurin-NFAT signaling cascade	10	6.79e-01	7.55e-02	9.01e-01
GO:0030217 T cell differentiation	18	5.80e-01	7.54e-02	8.51e-01
GO:0032735 positive regulation of interleukin-12 production	12	6.52e-01	7.53e-02	8.96e-01
GO:0043235 receptor complex	79	2.49e-01	7.51e-02	6.27e-01
GO:0003677 DNA binding	339	1.82e-02	-7.49e-02	2.25e-01
GO:0000122 negative regulation of transcription by RNA polymerase II	395	1.11e-02	-7.48e-02	1.79e-01
GO:0004843 cysteine-type deubiquitinase activity	58	3.26e-01	-7.46e-02	6.99e-01
GO:0071949 FAD binding	27	5.02e-01	7.46e-02	8.05e-01
GO:0000939 inner kinetochore	10	6.83e-01	7.46e-02	9.01e-01
GO:0050821 protein stabilization	109	1.81e-01	-7.42e-02	5.40e-01
GO:0030220 platelet formation	11	6.71e-01	-7.41e-02	8.97e-01
GO:0035613 RNA stem-loop binding	11	6.71e-01	-7.41e-02	8.97e-01
GO:0005525 GTP binding	212	6.38e-02	7.40e-02	3.55e-01
GO:0007416 synapse assembly	25	5.23e-01	7.38e-02	8.21e-01
GO:0008033 tRNA processing	15	6.21e-01	7.38e-02	8.78e-01
GO:0045494 photoreceptor cell maintenance	25	5.23e-01	7.38e-02	8.21e-01
GO:0042147 retrograde transport, endosome to Golgi	50	3.67e-01	7.37e-02	7.31e-01
GO:0006509 membrane protein ectodomain proteolysis	15	6.21e-01	-7.37e-02	8.78e-01
GO:0030425 dendrite	133	1.43e-01	-7.36e-02	4.77e-01
GO:0097190 apoptotic signaling pathway	20	5.70e-01	7.34e-02	8.46e-01
GO:2000773 negative regulation of cellular senescence	12	6.62e-01	7.30e-02	8.96e-01
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules	39	4.31e-01	-7.30e-02	7.67e-01
GO:0097194 execution phase of apoptosis	10	6.90e-01	7.28e-02	9.03e-01
GO:0048146 positive regulation of fibroblast proliferation	18	5.93e-01	-7.28e-02	8.62e-01
GO:0030307 positive regulation of cell growth	36	4.53e-01	-7.22e-02	7.76e-01
GO:0048705 skeletal system morphogenesis	15	6.29e-01	7.21e-02	8.85e-01
GO:1990244 histone H2AT120 kinase activity	31	4.89e-01	-7.18e-02	7.94e-01
GO:0060079 excitatory postsynaptic potential	17	6.09e-01	-7.17e-02	8.69e-01
GO:0045815 transcription initiation-coupled chromatin remodeling	20	5.80e-01	-7.15e-02	8.51e-01
GO:0070534 protein K63-linked ubiquitination	31	4.92e-01	-7.13e-02	7.95e-01
GO:0007611 learning or memory	15	6.33e-01	7.12e-02	8.89e-01
GO:0005770 late endosome	75	2.89e-01	7.09e-02	6.75e-01
GO:0005975 carbohydrate metabolic process	49	3.93e-01	7.06e-02	7.45e-01
GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway	15	6.36e-01	-7.05e-02	8.92e-01
GO:0035116 embryonic hindlimb morphogenesis	12	6.73e-01	7.05e-02	8.97e-01
GO:0006346 DNA methylation-dependent constitutive heterochromatin formation	10	7.00e-01	-7.03e-02	9.05e-01
GO:0005763 mitochondrial small ribosomal subunit	21	5.79e-01	7.00e-02	8.51e-01
GO:0005158 insulin receptor binding	13	6.63e-01	-6.98e-02	8.96e-01
GO:0006644 phospholipid metabolic process	11	6.89e-01	6.98e-02	9.02e-01
GO:0051787 misfolded protein binding	12	6.75e-01	6.98e-02	8.99e-01
GO:0050830 defense response to Gram-positive bacterium	15	6.40e-01	6.98e-02	8.94e-01
GO:0032259 methylation	76	2.94e-01	-6.97e-02	6.79e-01
GO:0005882 intermediate filament	20	5.90e-01	-6.96e-02	8.60e-01
GO:0005912 adherens junction	71	3.11e-01	6.95e-02	6.91e-01
GO:0043536 positive regulation of blood vessel endothelial cell migration	18	6.10e-01	6.95e-02	8.69e-01
GO:0005518 collagen binding	34	4.84e-01	-6.94e-02	7.91e-01
GO:0001764 neuron migration	40	4.48e-01	-6.93e-02	7.75e-01
GO:0004722 protein serine/threonine phosphatase activity	33	4.92e-01	-6.92e-02	7.95e-01
GO:0002931 response to ischemia	10	7.05e-01	-6.91e-02	9.10e-01
GO:0016567 protein ubiquitination	155	1.38e-01	-6.91e-02	4.69e-01
GO:0010575 positive regulation of vascular endothelial growth factor production	13	6.67e-01	6.88e-02	8.97e-01
GO:0001673 male germ cell nucleus	27	5.37e-01	6.87e-02	8.31e-01
GO:0030308 negative regulation of cell growth	42	4.42e-01	-6.87e-02	7.73e-01
GO:0007420 brain development	78	2.97e-01	-6.84e-02	6.81e-01
GO:0030215 semaphorin receptor binding	12	6.82e-01	-6.83e-02	9.01e-01
GO:0036158 outer dynein arm assembly	10	7.09e-01	6.82e-02	9.11e-01
GO:0051536 iron-sulfur cluster binding	12	6.83e-01	6.82e-02	9.01e-01
GO:0045880 positive regulation of smoothened signaling pathway	23	5.72e-01	-6.81e-02	8.48e-01
GO:0004721 phosphoprotein phosphatase activity	21	5.89e-01	-6.81e-02	8.59e-01
GO:0016197 endosomal transport	27	5.41e-01	6.79e-02	8.31e-01
GO:0030154 cell differentiation	141	1.65e-01	-6.79e-02	5.16e-01
GO:0005794 Golgi apparatus	466	1.26e-02	6.78e-02	1.87e-01
GO:0006612 protein targeting to membrane	24	5.65e-01	6.78e-02	8.44e-01
GO:0007286 spermatid development	25	5.58e-01	-6.77e-02	8.41e-01
GO:0006006 glucose metabolic process	26	5.51e-01	-6.75e-02	8.35e-01
GO:0070840 dynein complex binding	11	6.98e-01	6.75e-02	9.04e-01
GO:0051537 2 iron, 2 sulfur cluster binding	17	6.31e-01	6.73e-02	8.87e-01
GO:0005741 mitochondrial outer membrane	95	2.58e-01	-6.72e-02	6.39e-01
GO:0042645 mitochondrial nucleoid	37	4.80e-01	-6.71e-02	7.91e-01
GO:0046835 carbohydrate phosphorylation	20	6.04e-01	-6.71e-02	8.68e-01
GO:0005783 endoplasmic reticulum	434	1.71e-02	6.71e-02	2.21e-01
GO:0000118 histone deacetylase complex	22	5.89e-01	6.66e-02	8.59e-01
GO:0009898 cytoplasmic side of plasma membrane	48	4.25e-01	6.66e-02	7.62e-01
GO:0005886 plasma membrane	1534	2.02e-05	6.64e-02	3.98e-03
GO:0006506 GPI anchor biosynthetic process	25	5.68e-01	6.60e-02	8.44e-01
GO:0016460 myosin II complex	12	6.93e-01	-6.59e-02	9.03e-01
GO:0003333 amino acid transmembrane transport	10	7.19e-01	6.58e-02	9.14e-01
GO:0016485 protein processing	40	4.72e-01	6.58e-02	7.88e-01
GO:0010824 regulation of centrosome duplication	15	6.59e-01	-6.57e-02	8.96e-01
GO:0022857 transmembrane transporter activity	41	4.69e-01	-6.54e-02	7.88e-01
GO:0004715 non-membrane spanning protein tyrosine kinase activity	20	6.13e-01	6.53e-02	8.73e-01
GO:0005789 endoplasmic reticulum membrane	405	2.48e-02	6.53e-02	2.60e-01
GO:0034644 cellular response to UV	33	5.17e-01	-6.52e-02	8.19e-01
GO:0006337 nucleosome disassembly	10	7.21e-01	-6.51e-02	9.14e-01
GO:0030145 manganese ion binding	45	4.50e-01	-6.51e-02	7.75e-01
GO:0032206 positive regulation of telomere maintenance	13	6.85e-01	-6.51e-02	9.02e-01
GO:0006355 regulation of DNA-templated transcription	160	1.57e-01	-6.49e-02	5.03e-01
GO:0000278 mitotic cell cycle	53	4.14e-01	6.49e-02	7.55e-01
GO:0030317 flagellated sperm motility	29	5.47e-01	6.46e-02	8.33e-01
GO:0016324 apical plasma membrane	123	2.17e-01	6.45e-02	5.94e-01
GO:0007129 homologous chromosome pairing at meiosis	13	6.87e-01	-6.45e-02	9.02e-01
GO:0005615 extracellular space	401	2.77e-02	6.44e-02	2.65e-01
GO:0061744 motor behavior	16	6.56e-01	-6.43e-02	8.96e-01
GO:0010467 gene expression	80	3.20e-01	6.43e-02	6.95e-01
GO:0031902 late endosome membrane	67	3.66e-01	6.39e-02	7.31e-01
GO:0048675 axon extension	18	6.39e-01	-6.39e-02	8.94e-01
GO:0019903 protein phosphatase binding	49	4.41e-01	6.37e-02	7.72e-01
GO:0006351 DNA-templated transcription	36	5.09e-01	-6.36e-02	8.12e-01
GO:0016579 protein deubiquitination	28	5.60e-01	6.36e-02	8.42e-01
GO:0070402 NADPH binding	10	7.28e-01	6.36e-02	9.14e-01
GO:0045665 negative regulation of neuron differentiation	25	5.83e-01	-6.35e-02	8.54e-01
GO:0045727 positive regulation of translation	36	5.11e-01	6.33e-02	8.14e-01
GO:0007029 endoplasmic reticulum organization	16	6.61e-01	6.32e-02	8.96e-01
GO:0019843 rRNA binding	22	6.09e-01	-6.30e-02	8.69e-01
GO:0035979 histone H2AXS139 kinase activity	32	5.39e-01	-6.28e-02	8.31e-01
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II	12	7.07e-01	-6.28e-02	9.10e-01
GO:0045773 positive regulation of axon extension	11	7.19e-01	-6.28e-02	9.14e-01
GO:0042995 cell projection	54	4.26e-01	6.26e-02	7.63e-01
GO:0007015 actin filament organization	70	3.66e-01	6.26e-02	7.31e-01
GO:0030971 receptor tyrosine kinase binding	32	5.43e-01	6.21e-02	8.31e-01
GO:0004222 metalloendopeptidase activity	50	4.49e-01	-6.20e-02	7.75e-01
GO:0045787 positive regulation of cell cycle	13	6.99e-01	6.19e-02	9.04e-01
GO:0030659 cytoplasmic vesicle membrane	43	4.83e-01	6.18e-02	7.91e-01
GO:0042813 Wnt receptor activity	13	7.00e-01	-6.18e-02	9.04e-01
GO:0006986 response to unfolded protein	12	7.12e-01	-6.16e-02	9.11e-01
GO:0006366 transcription by RNA polymerase II	73	3.63e-01	-6.16e-02	7.31e-01
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding	393	3.80e-02	-6.13e-02	2.93e-01
GO:0043010 camera-type eye development	22	6.19e-01	6.12e-02	8.78e-01
GO:0031267 small GTPase binding	167	1.73e-01	6.12e-02	5.32e-01
GO:0031122 cytoplasmic microtubule organization	28	5.76e-01	6.11e-02	8.49e-01
GO:2000786 positive regulation of autophagosome assembly	14	6.93e-01	-6.10e-02	9.03e-01
GO:0005819 spindle	54	4.38e-01	6.10e-02	7.72e-01
GO:0051018 protein kinase A binding	12	7.15e-01	-6.09e-02	9.12e-01
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific	347	5.26e-02	-6.08e-02	3.33e-01
GO:0032508 DNA duplex unwinding	44	4.86e-01	-6.08e-02	7.91e-01
GO:0006629 lipid metabolic process	52	4.49e-01	6.07e-02	7.75e-01
GO:0031418 L-ascorbic acid binding	14	6.96e-01	6.03e-02	9.04e-01
GO:0016787 hydrolase activity	108	2.80e-01	-6.02e-02	6.64e-01
GO:0045454 cell redox homeostasis	20	6.41e-01	6.02e-02	8.94e-01
GO:0090303 positive regulation of wound healing	11	7.33e-01	5.94e-02	9.16e-01
GO:0045724 positive regulation of cilium assembly	13	7.11e-01	5.93e-02	9.11e-01
GO:1990498 mitotic spindle microtubule	10	7.45e-01	5.93e-02	9.21e-01
GO:0043204 perikaryon	35	5.44e-01	5.93e-02	8.31e-01
GO:0010629 negative regulation of gene expression	101	3.05e-01	5.91e-02	6.90e-01
GO:0001784 phosphotyrosine residue binding	27	5.96e-01	-5.90e-02	8.62e-01
GO:0006400 tRNA modification	12	7.24e-01	5.89e-02	9.14e-01
GO:0001708 cell fate specification	12	7.25e-01	-5.87e-02	9.14e-01
GO:0032211 negative regulation of telomere maintenance via telomerase	10	7.48e-01	-5.87e-02	9.21e-01
GO:0030150 protein import into mitochondrial matrix	12	7.26e-01	5.84e-02	9.14e-01
GO:0007399 nervous system development	89	3.42e-01	-5.84e-02	7.09e-01
GO:0000381 regulation of alternative mRNA splicing, via spliceosome	31	5.75e-01	-5.82e-02	8.49e-01
GO:0016358 dendrite development	19	6.63e-01	5.78e-02	8.96e-01
GO:0005007 fibroblast growth factor receptor activity	13	7.21e-01	-5.73e-02	9.14e-01
GO:0097110 scaffold protein binding	28	6.01e-01	-5.71e-02	8.67e-01
GO:0005778 peroxisomal membrane	28	6.02e-01	5.70e-02	8.67e-01
GO:0015035 protein-disulfide reductase activity	14	7.12e-01	5.69e-02	9.11e-01
GO:0035264 multicellular organism growth	67	4.22e-01	-5.68e-02	7.59e-01
GO:0045892 negative regulation of DNA-templated transcription	173	2.00e-01	-5.66e-02	5.68e-01
GO:0004497 monooxygenase activity	11	7.46e-01	5.64e-02	9.21e-01
GO:0050660 flavin adenine dinucleotide binding	33	5.77e-01	5.61e-02	8.49e-01
GO:0046856 phosphatidylinositol dephosphorylation	26	6.21e-01	-5.61e-02	8.78e-01
GO:0048568 embryonic organ development	15	7.07e-01	-5.61e-02	9.10e-01
GO:0045595 regulation of cell differentiation	13	7.26e-01	-5.61e-02	9.14e-01
GO:0070062 extracellular exosome	40	5.42e-01	5.57e-02	8.31e-01
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway	41	5.40e-01	-5.53e-02	8.31e-01
GO:0000776 kinetochore	90	3.65e-01	5.53e-02	7.31e-01
GO:0070371 ERK1 and ERK2 cascade	19	6.77e-01	5.53e-02	8.99e-01
GO:0030507 spectrin binding	12	7.40e-01	5.52e-02	9.21e-01
GO:0140627 ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	10	7.63e-01	5.52e-02	9.26e-01
GO:0032481 positive regulation of type I interferon production	18	6.86e-01	5.51e-02	9.02e-01
GO:0052689 carboxylic ester hydrolase activity	12	7.41e-01	-5.51e-02	9.21e-01
GO:0001569 branching involved in blood vessel morphogenesis	15	7.13e-01	-5.49e-02	9.11e-01
GO:0045648 positive regulation of erythrocyte differentiation	18	6.87e-01	-5.48e-02	9.02e-01
GO:0015031 protein transport	173	2.16e-01	5.46e-02	5.92e-01
GO:0140693 molecular condensate scaffold activity	24	6.43e-01	-5.46e-02	8.94e-01
GO:0000387 spliceosomal snRNP assembly	17	6.97e-01	-5.46e-02	9.04e-01
GO:0045672 positive regulation of osteoclast differentiation	11	7.54e-01	5.45e-02	9.24e-01
GO:0016887 ATP hydrolysis activity	218	1.67e-01	-5.45e-02	5.19e-01
GO:0008285 negative regulation of cell population proliferation	115	3.17e-01	5.41e-02	6.95e-01
GO:0010314 phosphatidylinositol-5-phosphate binding	11	7.56e-01	5.40e-02	9.24e-01
GO:0003755 peptidyl-prolyl cis-trans isomerase activity	30	6.09e-01	-5.40e-02	8.69e-01
GO:0006402 mRNA catabolic process	14	7.27e-01	-5.39e-02	9.14e-01
GO:0030032 lamellipodium assembly	21	6.71e-01	5.35e-02	8.97e-01
GO:0007165 signal transduction	263	1.38e-01	5.33e-02	4.69e-01
GO:0008270 zinc ion binding	402	6.78e-02	-5.33e-02	3.62e-01
GO:0000993 RNA polymerase II complex binding	23	6.59e-01	-5.32e-02	8.96e-01
GO:0031625 ubiquitin protein ligase binding	173	2.29e-01	-5.31e-02	6.09e-01
GO:0140823 histone H2BS36 kinase activity	31	6.09e-01	-5.31e-02	8.69e-01
GO:0030246 carbohydrate binding	40	5.62e-01	-5.30e-02	8.43e-01
GO:0008233 peptidase activity	10	7.72e-01	-5.30e-02	9.28e-01
GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction	21	6.75e-01	-5.28e-02	8.99e-01
GO:0005759 mitochondrial matrix	120	3.18e-01	5.28e-02	6.95e-01
GO:0006284 base-excision repair	17	7.08e-01	-5.26e-02	9.10e-01
GO:0043124 negative regulation of canonical NF-kappaB signal transduction	35	5.93e-01	-5.23e-02	8.62e-01
GO:0042149 cellular response to glucose starvation	29	6.26e-01	5.23e-02	8.83e-01
GO:0034976 response to endoplasmic reticulum stress	33	6.04e-01	-5.22e-02	8.68e-01
GO:0030324 lung development	35	5.94e-01	-5.21e-02	8.62e-01
GO:0032580 Golgi cisterna membrane	27	6.41e-01	-5.19e-02	8.94e-01
GO:0050796 regulation of insulin secretion	12	7.56e-01	5.19e-02	9.24e-01
GO:0051216 cartilage development	21	6.83e-01	5.14e-02	9.01e-01
GO:0048706 embryonic skeletal system development	15	7.30e-01	5.14e-02	9.16e-01
GO:0007030 Golgi organization	63	4.81e-01	5.14e-02	7.91e-01
GO:0042162 telomeric DNA binding	20	6.91e-01	5.13e-02	9.03e-01
GO:0050767 regulation of neurogenesis	14	7.41e-01	-5.11e-02	9.21e-01
GO:0043014 alpha-tubulin binding	23	6.72e-01	5.11e-02	8.97e-01
GO:0010507 negative regulation of autophagy	22	6.79e-01	-5.11e-02	9.01e-01
GO:1902018 negative regulation of cilium assembly	13	7.50e-01	-5.10e-02	9.23e-01
GO:0000956 nuclear-transcribed mRNA catabolic process	12	7.60e-01	5.09e-02	9.25e-01
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding	12	7.60e-01	-5.09e-02	9.25e-01
GO:0007608 sensory perception of smell	11	7.70e-01	5.09e-02	9.28e-01
GO:1990023 mitotic spindle midzone	10	7.81e-01	-5.09e-02	9.28e-01
GO:0035019 somatic stem cell population maintenance	31	6.24e-01	-5.08e-02	8.81e-01
GO:0031491 nucleosome binding	25	6.62e-01	-5.05e-02	8.96e-01
GO:0003785 actin monomer binding	14	7.44e-01	5.04e-02	9.21e-01
GO:0060218 hematopoietic stem cell differentiation	11	7.73e-01	5.02e-02	9.28e-01
GO:0051059 NF-kappaB binding	22	6.87e-01	4.96e-02	9.02e-01
GO:0008320 protein transmembrane transporter activity	11	7.76e-01	-4.96e-02	9.28e-01
GO:0017147 Wnt-protein binding	18	7.18e-01	4.91e-02	9.14e-01
GO:0010506 regulation of autophagy	26	6.65e-01	4.91e-02	8.97e-01
GO:0070300 phosphatidic acid binding	13	7.60e-01	-4.90e-02	9.25e-01
GO:0051019 mitogen-activated protein kinase binding	11	7.79e-01	-4.90e-02	9.28e-01
GO:0030970 retrograde protein transport, ER to cytosol	12	7.69e-01	4.89e-02	9.28e-01
GO:0010811 positive regulation of cell-substrate adhesion	13	7.61e-01	-4.88e-02	9.25e-01
GO:0001702 gastrulation with mouth forming second	10	7.89e-01	4.88e-02	9.33e-01
GO:0031966 mitochondrial membrane	38	6.03e-01	4.87e-02	8.68e-01
GO:0006413 translational initiation	30	6.44e-01	-4.87e-02	8.94e-01
GO:0045296 cadherin binding	29	6.51e-01	4.86e-02	8.96e-01
GO:0017134 fibroblast growth factor binding	12	7.73e-01	4.82e-02	9.28e-01
GO:0005739 mitochondrion	607	4.52e-02	4.79e-02	3.15e-01
GO:0048538 thymus development	22	6.98e-01	-4.78e-02	9.04e-01
GO:0006935 chemotaxis	14	7.57e-01	4.77e-02	9.25e-01
GO:0005768 endosome	113	3.83e-01	4.76e-02	7.41e-01
GO:0004674 protein serine/threonine kinase activity	203	2.44e-01	-4.76e-02	6.19e-01
GO:0043531 ADP binding	21	7.06e-01	-4.75e-02	9.10e-01
GO:0007281 germ cell development	14	7.58e-01	-4.75e-02	9.25e-01
GO:0042552 myelination	28	6.65e-01	4.72e-02	8.97e-01
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle	23	6.95e-01	4.72e-02	9.04e-01
GO:0035402 histone H3T11 kinase activity	30	6.56e-01	-4.69e-02	8.96e-01
GO:0044022 histone H3S28 kinase activity	30	6.56e-01	-4.69e-02	8.96e-01
GO:0044023 histone H4S1 kinase activity	30	6.56e-01	-4.69e-02	8.96e-01
GO:0044024 histone H2AS1 kinase activity	30	6.56e-01	-4.69e-02	8.96e-01
GO:0044025 histone H2BS14 kinase activity	30	6.56e-01	-4.69e-02	8.96e-01
GO:0072371 histone H2AS121 kinase activity	30	6.56e-01	-4.69e-02	8.96e-01
GO:0140855 histone H3S57 kinase activity	30	6.56e-01	-4.69e-02	8.96e-01
GO:0140857 histone H3T45 kinase activity	30	6.56e-01	-4.69e-02	8.96e-01
GO:0007249 canonical NF-kappaB signal transduction	18	7.31e-01	-4.68e-02	9.16e-01
GO:0040018 positive regulation of multicellular organism growth	16	7.46e-01	-4.67e-02	9.21e-01
GO:0098586 cellular response to virus	22	7.05e-01	-4.66e-02	9.10e-01
GO:0035023 regulation of Rho protein signal transduction	16	7.47e-01	4.65e-02	9.21e-01
GO:0097009 energy homeostasis	23	6.99e-01	-4.65e-02	9.04e-01
GO:0042127 regulation of cell population proliferation	45	5.90e-01	4.64e-02	8.60e-01
GO:0016042 lipid catabolic process	29	6.67e-01	4.62e-02	8.97e-01
GO:0008289 lipid binding	45	5.93e-01	4.60e-02	8.62e-01
GO:0060325 face morphogenesis	20	7.22e-01	4.60e-02	9.14e-01
GO:0048863 stem cell differentiation	22	7.09e-01	-4.60e-02	9.11e-01
GO:0008045 motor neuron axon guidance	12	7.83e-01	-4.59e-02	9.29e-01
GO:0050727 regulation of inflammatory response	27	6.81e-01	-4.57e-02	9.01e-01
GO:0070628 proteasome binding	13	7.76e-01	-4.56e-02	9.28e-01
GO:0008277 regulation of G protein-coupled receptor signaling pathway	16	7.52e-01	4.56e-02	9.24e-01
GO:0043539 protein serine/threonine kinase activator activity	34	6.47e-01	4.54e-02	8.96e-01
GO:0035175 histone H3S10 kinase activity	31	6.62e-01	-4.53e-02	8.96e-01
GO:0072354 histone H3T3 kinase activity	31	6.62e-01	-4.53e-02	8.96e-01
GO:0042254 ribosome biogenesis	16	7.55e-01	-4.51e-02	9.24e-01
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	66	5.28e-01	4.50e-02	8.26e-01
GO:0006893 Golgi to plasma membrane transport	19	7.34e-01	-4.50e-02	9.17e-01
GO:0045165 cell fate commitment	21	7.21e-01	-4.50e-02	9.14e-01
GO:0016020 membrane	950	2.05e-02	4.49e-02	2.31e-01
GO:0046982 protein heterodimerization activity	132	3.75e-01	4.48e-02	7.32e-01
GO:0043001 Golgi to plasma membrane protein transport	21	7.23e-01	4.48e-02	9.14e-01
GO:0006879 intracellular iron ion homeostasis	31	6.67e-01	-4.46e-02	8.97e-01
GO:0003730 mRNA 3’-UTR binding	51	5.82e-01	4.46e-02	8.53e-01
GO:0030036 actin cytoskeleton organization	108	4.24e-01	-4.46e-02	7.60e-01
GO:0003684 damaged DNA binding	34	6.54e-01	4.45e-02	8.96e-01
GO:0055013 cardiac muscle cell development	11	7.98e-01	4.45e-02	9.39e-01
GO:0051965 positive regulation of synapse assembly	22	7.19e-01	4.43e-02	9.14e-01
GO:0046580 negative regulation of Ras protein signal transduction	13	7.83e-01	-4.42e-02	9.29e-01
GO:0070847 core mediator complex	19	7.39e-01	4.41e-02	9.21e-01
GO:0044877 protein-containing complex binding	105	4.36e-01	4.41e-02	7.69e-01
GO:0002244 hematopoietic progenitor cell differentiation	35	6.56e-01	4.36e-02	8.96e-01
GO:0016604 nuclear body	174	3.25e-01	-4.34e-02	6.99e-01
GO:0045600 positive regulation of fat cell differentiation	22	7.25e-01	4.34e-02	9.14e-01
GO:0001707 mesoderm formation	15	7.72e-01	-4.31e-02	9.28e-01
GO:0044291 cell-cell contact zone	13	7.88e-01	-4.31e-02	9.32e-01
GO:0005654 nucleoplasm	1532	5.88e-03	-4.30e-02	1.41e-01
GO:0051453 regulation of intracellular pH	14	7.81e-01	-4.29e-02	9.28e-01
GO:0005829 cytosol	2019	2.08e-03	4.26e-02	8.98e-02
GO:0033344 cholesterol efflux	11	8.07e-01	4.25e-02	9.41e-01
GO:0000049 tRNA binding	52	5.97e-01	-4.24e-02	8.63e-01
GO:0016592 mediator complex	28	6.98e-01	-4.23e-02	9.04e-01
GO:0004677 DNA-dependent protein kinase activity	31	6.84e-01	-4.23e-02	9.01e-01
GO:0004521 RNA endonuclease activity	20	7.44e-01	4.22e-02	9.21e-01
GO:0051865 protein autoubiquitination	39	6.49e-01	4.21e-02	8.96e-01
GO:0048839 inner ear development	12	8.02e-01	4.19e-02	9.40e-01
GO:0001822 kidney development	51	6.05e-01	-4.18e-02	8.69e-01
GO:0043627 response to estrogen	10	8.19e-01	-4.18e-02	9.43e-01
GO:0043130 ubiquitin binding	61	5.75e-01	-4.16e-02	8.49e-01
GO:0010628 positive regulation of gene expression	146	3.87e-01	4.15e-02	7.44e-01
GO:0070374 positive regulation of ERK1 and ERK2 cascade	60	5.79e-01	4.15e-02	8.51e-01
GO:0043015 gamma-tubulin binding	21	7.43e-01	4.14e-02	9.21e-01
GO:0003690 double-stranded DNA binding	35	6.72e-01	4.14e-02	8.97e-01
GO:0043525 positive regulation of neuron apoptotic process	18	7.62e-01	-4.13e-02	9.26e-01
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding	84	5.13e-01	-4.13e-02	8.16e-01
GO:0031648 protein destabilization	32	6.87e-01	-4.12e-02	9.02e-01
GO:0051028 mRNA transport	27	7.11e-01	-4.12e-02	9.11e-01
GO:0048513 animal organ development	11	8.13e-01	-4.12e-02	9.43e-01
GO:0000175 3’-5’-RNA exonuclease activity	21	7.46e-01	-4.09e-02	9.21e-01
GO:0043488 regulation of mRNA stability	16	7.77e-01	-4.09e-02	9.28e-01
GO:0031507 heterochromatin formation	27	7.13e-01	-4.09e-02	9.11e-01
GO:0097550 transcription preinitiation complex	12	8.06e-01	4.09e-02	9.41e-01
GO:0034497 protein localization to phagophore assembly site	11	8.16e-01	-4.05e-02	9.43e-01
GO:0051604 protein maturation	20	7.54e-01	-4.05e-02	9.24e-01
GO:0009952 anterior/posterior pattern specification	42	6.50e-01	-4.05e-02	8.96e-01
GO:0005743 mitochondrial inner membrane	180	3.51e-01	4.04e-02	7.21e-01
GO:0016323 basolateral plasma membrane	96	4.95e-01	4.03e-02	7.98e-01
GO:0006915 apoptotic process	135	4.19e-01	4.03e-02	7.58e-01
GO:0003887 DNA-directed DNA polymerase activity	16	7.81e-01	4.02e-02	9.28e-01
GO:0030593 neutrophil chemotaxis	13	8.06e-01	3.94e-02	9.41e-01
GO:0015630 microtubule cytoskeleton	71	5.67e-01	3.94e-02	8.44e-01
GO:0051290 protein heterotetramerization	10	8.30e-01	3.93e-02	9.45e-01
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway	19	7.67e-01	3.93e-02	9.28e-01
GO:0001678 intracellular glucose homeostasis	17	7.79e-01	3.92e-02	9.28e-01
GO:0007254 JNK cascade	24	7.40e-01	-3.92e-02	9.21e-01
GO:0022904 respiratory electron transport chain	14	8.01e-01	3.90e-02	9.40e-01
GO:0005758 mitochondrial intermembrane space	47	6.44e-01	3.90e-02	8.94e-01
GO:0015813 L-glutamate transmembrane transport	11	8.23e-01	3.90e-02	9.43e-01
GO:0035098 ESC/E(Z) complex	12	8.16e-01	3.88e-02	9.43e-01
GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction	35	6.92e-01	-3.87e-02	9.03e-01
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle	26	7.33e-01	3.87e-02	9.16e-01
GO:0051209 release of sequestered calcium ion into cytosol	19	7.70e-01	3.87e-02	9.28e-01
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT	13	8.10e-01	3.85e-02	9.43e-01
GO:0090443 FAR/SIN/STRIPAK complex	12	8.18e-01	3.84e-02	9.43e-01
GO:0005635 nuclear envelope	77	5.61e-01	-3.83e-02	8.42e-01
GO:0007338 single fertilization	19	7.72e-01	3.83e-02	9.28e-01
GO:0042593 glucose homeostasis	42	6.68e-01	-3.82e-02	8.97e-01
GO:0019221 cytokine-mediated signaling pathway	46	6.54e-01	3.82e-02	8.96e-01
GO:0044297 cell body	23	7.53e-01	3.79e-02	9.24e-01
GO:0046330 positive regulation of JNK cascade	37	6.94e-01	-3.74e-02	9.03e-01
GO:0008284 positive regulation of cell population proliferation	158	4.19e-01	3.73e-02	7.58e-01
GO:0035249 synaptic transmission, glutamatergic	17	7.91e-01	3.71e-02	9.35e-01
GO:0004714 transmembrane receptor protein tyrosine kinase activity	14	8.10e-01	3.70e-02	9.43e-01
GO:0050769 positive regulation of neurogenesis	12	8.25e-01	-3.69e-02	9.45e-01
GO:0035861 site of double-strand break	58	6.28e-01	-3.68e-02	8.84e-01
GO:0012505 endomembrane system	97	5.33e-01	-3.67e-02	8.29e-01
GO:0071816 tail-anchored membrane protein insertion into ER membrane	10	8.43e-01	3.62e-02	9.48e-01
GO:0051015 actin filament binding	119	4.97e-01	3.61e-02	7.99e-01
GO:0008021 synaptic vesicle	47	6.69e-01	-3.60e-02	8.97e-01
GO:0031397 negative regulation of protein ubiquitination	33	7.21e-01	3.60e-02	9.14e-01
GO:0008104 protein localization	66	6.14e-01	3.59e-02	8.73e-01
GO:0120009 intermembrane lipid transfer	16	8.04e-01	-3.59e-02	9.41e-01
GO:0032456 endocytic recycling	42	6.88e-01	3.58e-02	9.02e-01
GO:0043138 3’-5’ DNA helicase activity	10	8.46e-01	-3.56e-02	9.48e-01
GO:0060348 bone development	27	7.49e-01	3.55e-02	9.22e-01
GO:0051302 regulation of cell division	11	8.39e-01	-3.54e-02	9.48e-01
GO:0006310 DNA recombination	23	7.72e-01	3.50e-02	9.28e-01
GO:0004679 AMP-activated protein kinase activity	32	7.33e-01	-3.48e-02	9.16e-01
GO:0045668 negative regulation of osteoblast differentiation	27	7.55e-01	3.47e-02	9.24e-01
GO:0060586 multicellular organismal-level iron ion homeostasis	16	8.10e-01	3.46e-02	9.43e-01
GO:0000502 proteasome complex	13	8.29e-01	3.46e-02	9.45e-01
GO:0070888 E-box binding	21	7.84e-01	-3.45e-02	9.29e-01
GO:1901673 regulation of mitotic spindle assembly	16	8.11e-01	-3.45e-02	9.43e-01
GO:0051539 4 iron, 4 sulfur cluster binding	33	7.32e-01	-3.45e-02	9.16e-01
GO:0046332 SMAD binding	23	7.75e-01	-3.45e-02	9.28e-01
GO:0051117 ATPase binding	44	6.93e-01	3.44e-02	9.03e-01
GO:0070530 K63-linked polyubiquitin modification-dependent protein binding	18	8.01e-01	-3.44e-02	9.40e-01
GO:0031297 replication fork processing	26	7.62e-01	3.43e-02	9.26e-01
GO:0007507 heart development	80	5.97e-01	-3.42e-02	8.63e-01
GO:0045111 intermediate filament cytoskeleton	23	7.77e-01	3.41e-02	9.28e-01
GO:0050728 negative regulation of inflammatory response	48	6.84e-01	-3.40e-02	9.01e-01
GO:0031647 regulation of protein stability	57	6.58e-01	3.40e-02	8.96e-01
GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	77	6.07e-01	-3.40e-02	8.69e-01
GO:0000165 MAPK cascade	46	6.91e-01	-3.39e-02	9.03e-01
GO:0034237 protein kinase A regulatory subunit binding	15	8.21e-01	3.38e-02	9.43e-01
GO:0019888 protein phosphatase regulator activity	16	8.15e-01	-3.38e-02	9.43e-01
GO:0001755 neural crest cell migration	26	7.66e-01	3.37e-02	9.28e-01
GO:0035904 aorta development	15	8.22e-01	3.35e-02	9.43e-01
GO:0030514 negative regulation of BMP signaling pathway	26	7.67e-01	-3.35e-02	9.28e-01
GO:0060612 adipose tissue development	23	7.81e-01	3.35e-02	9.28e-01
GO:0016226 iron-sulfur cluster assembly	17	8.12e-01	3.33e-02	9.43e-01
GO:0030374 nuclear receptor coactivator activity	30	7.52e-01	-3.33e-02	9.24e-01
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	28	7.61e-01	3.33e-02	9.25e-01
GO:0046872 metal ion binding	874	1.01e-01	-3.31e-02	4.21e-01
GO:0042177 negative regulation of protein catabolic process	24	7.80e-01	-3.30e-02	9.28e-01
GO:0043410 positive regulation of MAPK cascade	61	6.57e-01	3.29e-02	8.96e-01
GO:0047496 vesicle transport along microtubule	11	8.50e-01	3.29e-02	9.51e-01
GO:0005543 phospholipid binding	38	7.27e-01	3.27e-02	9.14e-01
GO:0005576 extracellular region	240	3.86e-01	3.26e-02	7.44e-01
GO:0090263 positive regulation of canonical Wnt signaling pathway	62	6.62e-01	-3.22e-02	8.96e-01
GO:0140359 ABC-type transporter activity	12	8.49e-01	-3.18e-02	9.50e-01
GO:0001669 acrosomal vesicle	27	7.75e-01	3.18e-02	9.28e-01
GO:0007155 cell adhesion	106	5.72e-01	-3.18e-02	8.48e-01
GO:0030838 positive regulation of actin filament polymerization	26	7.80e-01	3.16e-02	9.28e-01
GO:0007267 cell-cell signaling	13	8.44e-01	-3.16e-02	9.48e-01
GO:0005262 calcium channel activity	22	7.99e-01	3.14e-02	9.39e-01
GO:0060041 retina development in camera-type eye	21	8.04e-01	-3.13e-02	9.41e-01
GO:0001843 neural tube closure	47	7.11e-01	3.13e-02	9.11e-01
GO:0097602 cullin family protein binding	16	8.29e-01	3.12e-02	9.45e-01
GO:0120162 positive regulation of cold-induced thermogenesis	30	7.67e-01	3.12e-02	9.28e-01
GO:0030139 endocytic vesicle	37	7.44e-01	3.11e-02	9.21e-01
GO:0009411 response to UV	23	7.97e-01	-3.10e-02	9.39e-01
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific	182	4.74e-01	-3.08e-02	7.88e-01
GO:0030165 PDZ domain binding	30	7.70e-01	-3.08e-02	9.28e-01
GO:1901981 phosphatidylinositol phosphate binding	16	8.31e-01	3.08e-02	9.45e-01
GO:0061631 ubiquitin conjugating enzyme activity	24	7.95e-01	3.06e-02	9.38e-01
GO:0007160 cell-matrix adhesion	38	7.45e-01	-3.05e-02	9.21e-01
GO:0099171 presynaptic modulation of chemical synaptic transmission	11	8.61e-01	3.05e-02	9.54e-01
GO:0032722 positive regulation of chemokine production	11	8.61e-01	3.04e-02	9.54e-01
GO:0006954 inflammatory response	80	6.42e-01	3.01e-02	8.94e-01
GO:0098978 glutamatergic synapse	232	4.35e-01	2.99e-02	7.67e-01
GO:0007264 small GTPase-mediated signal transduction	46	7.26e-01	-2.98e-02	9.14e-01
GO:0006446 regulation of translational initiation	17	8.31e-01	2.98e-02	9.45e-01
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity	15	8.42e-01	-2.97e-02	9.48e-01
GO:0032874 positive regulation of stress-activated MAPK cascade	11	8.65e-01	2.97e-02	9.56e-01
GO:0035556 intracellular signal transduction	187	4.85e-01	2.97e-02	7.91e-01
GO:0001525 angiogenesis	85	6.38e-01	2.95e-02	8.94e-01
GO:0008360 regulation of cell shape	60	6.93e-01	-2.95e-02	9.03e-01
GO:0016740 transferase activity	23	8.07e-01	-2.95e-02	9.41e-01
GO:0061564 axon development	13	8.54e-01	2.95e-02	9.52e-01
GO:0045879 negative regulation of smoothened signaling pathway	16	8.39e-01	2.93e-02	9.48e-01
GO:0048015 phosphatidylinositol-mediated signaling	18	8.29e-01	2.93e-02	9.45e-01
GO:0003007 heart morphogenesis	16	8.40e-01	-2.91e-02	9.48e-01
GO:0099560 synaptic membrane adhesion	15	8.46e-01	-2.89e-02	9.49e-01
GO:0030206 chondroitin sulfate biosynthetic process	11	8.68e-01	2.89e-02	9.56e-01
GO:1990837 sequence-specific double-stranded DNA binding	47	7.33e-01	-2.88e-02	9.16e-01
GO:0003151 outflow tract morphogenesis	19	8.28e-01	2.88e-02	9.45e-01
GO:0006611 protein export from nucleus	22	8.16e-01	-2.87e-02	9.43e-01
GO:0090201 negative regulation of release of cytochrome c from mitochondria	11	8.70e-01	-2.85e-02	9.57e-01
GO:0036297 interstrand cross-link repair	24	8.12e-01	2.81e-02	9.43e-01
GO:0042472 inner ear morphogenesis	27	8.02e-01	-2.80e-02	9.40e-01
GO:0015629 actin cytoskeleton	114	6.10e-01	-2.77e-02	8.69e-01
GO:0045087 innate immune response	80	6.68e-01	2.77e-02	8.97e-01
GO:0030183 B cell differentiation	27	8.05e-01	-2.74e-02	9.41e-01
GO:0007186 G protein-coupled receptor signaling pathway	92	6.50e-01	-2.74e-02	8.96e-01
GO:0004930 G protein-coupled receptor activity	58	7.20e-01	-2.72e-02	9.14e-01
GO:0001541 ovarian follicle development	19	8.38e-01	2.72e-02	9.48e-01
GO:0045171 intercellular bridge	55	7.28e-01	2.71e-02	9.14e-01
GO:0043021 ribonucleoprotein complex binding	23	8.22e-01	-2.71e-02	9.43e-01
GO:0043123 positive regulation of canonical NF-kappaB signal transduction	76	6.84e-01	2.71e-02	9.01e-01
GO:0090141 positive regulation of mitochondrial fission	16	8.52e-01	-2.69e-02	9.52e-01
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	32	7.92e-01	2.69e-02	9.35e-01
GO:0002053 positive regulation of mesenchymal cell proliferation	10	8.83e-01	2.68e-02	9.59e-01
GO:0061462 protein localization to lysosome	10	8.84e-01	2.67e-02	9.59e-01
GO:0030155 regulation of cell adhesion	19	8.41e-01	2.66e-02	9.48e-01
GO:0006513 protein monoubiquitination	27	8.13e-01	-2.63e-02	9.43e-01
GO:0046326 positive regulation of D-glucose import	15	8.60e-01	-2.63e-02	9.54e-01
GO:0006695 cholesterol biosynthetic process	16	8.55e-01	-2.63e-02	9.52e-01
GO:0051382 kinetochore assembly	11	8.80e-01	-2.63e-02	9.59e-01
GO:0055085 transmembrane transport	88	6.71e-01	2.62e-02	8.97e-01
GO:0016853 isomerase activity	19	8.44e-01	2.61e-02	9.48e-01
GO:0008344 adult locomotory behavior	23	8.29e-01	-2.60e-02	9.45e-01
GO:0042752 regulation of circadian rhythm	27	8.16e-01	-2.59e-02	9.43e-01
GO:0030326 embryonic limb morphogenesis	14	8.67e-01	-2.59e-02	9.56e-01
GO:0008076 voltage-gated potassium channel complex	21	8.39e-01	-2.57e-02	9.48e-01
GO:0070273 phosphatidylinositol-4-phosphate binding	17	8.55e-01	-2.56e-02	9.52e-01
GO:0031463 Cul3-RING ubiquitin ligase complex	41	7.77e-01	2.56e-02	9.28e-01
GO:0045944 positive regulation of transcription by RNA polymerase II	526	3.18e-01	-2.56e-02	6.95e-01
GO:0003148 outflow tract septum morphogenesis	12	8.79e-01	-2.54e-02	9.59e-01
GO:0008543 fibroblast growth factor receptor signaling pathway	36	7.92e-01	-2.54e-02	9.35e-01
GO:0030833 regulation of actin filament polymerization	21	8.41e-01	-2.54e-02	9.48e-01
GO:0007004 telomere maintenance via telomerase	11	8.84e-01	-2.54e-02	9.59e-01
GO:0004842 ubiquitin-protein transferase activity	66	7.23e-01	-2.52e-02	9.14e-01
GO:0032991 protein-containing complex	207	5.34e-01	2.52e-02	8.29e-01
GO:0045785 positive regulation of cell adhesion	15	8.66e-01	-2.51e-02	9.56e-01
GO:0030216 keratinocyte differentiation	27	8.22e-01	-2.51e-02	9.43e-01
GO:0051607 defense response to virus	56	7.47e-01	-2.49e-02	9.21e-01
GO:0042470 melanosome	27	8.23e-01	2.49e-02	9.43e-01
GO:0071339 MLL1 complex	18	8.55e-01	2.49e-02	9.52e-01
GO:0007368 determination of left/right symmetry	28	8.20e-01	2.48e-02	9.43e-01
GO:0031941 filamentous actin	19	8.52e-01	-2.47e-02	9.52e-01
GO:0007409 axonogenesis	41	7.86e-01	-2.46e-02	9.31e-01
GO:0051017 actin filament bundle assembly	12	8.85e-01	2.42e-02	9.59e-01
GO:0006352 DNA-templated transcription initiation	11	8.90e-01	-2.41e-02	9.63e-01
GO:0005682 U5 snRNP	10	8.96e-01	-2.40e-02	9.65e-01
GO:0005102 signaling receptor binding	83	7.11e-01	-2.36e-02	9.11e-01
GO:0005923 bicellular tight junction	49	7.76e-01	2.35e-02	9.28e-01
GO:0043542 endothelial cell migration	14	8.80e-01	-2.34e-02	9.59e-01
GO:0005006 epidermal growth factor receptor activity	14	8.80e-01	-2.33e-02	9.59e-01
GO:0042605 peptide antigen binding	10	8.99e-01	-2.33e-02	9.66e-01
GO:0030335 positive regulation of cell migration	109	6.76e-01	-2.32e-02	8.99e-01
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation	30	8.26e-01	-2.32e-02	9.45e-01
GO:0030282 bone mineralization	24	8.44e-01	-2.32e-02	9.48e-01
GO:0005925 focal adhesion	113	6.73e-01	-2.30e-02	8.97e-01
GO:2000045 regulation of G1/S transition of mitotic cell cycle	19	8.62e-01	-2.30e-02	9.55e-01
GO:0060412 ventricular septum morphogenesis	18	8.66e-01	-2.29e-02	9.56e-01
GO:0033017 sarcoplasmic reticulum membrane	10	9.00e-01	-2.29e-02	9.66e-01
GO:0036342 post-anal tail morphogenesis	10	9.01e-01	2.27e-02	9.66e-01
GO:0003689 DNA clamp loader activity	32	8.25e-01	-2.26e-02	9.45e-01
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors	18	8.69e-01	2.25e-02	9.56e-01
GO:1990573 potassium ion import across plasma membrane	18	8.69e-01	2.25e-02	9.56e-01
GO:0106310 protein serine kinase activity	38	8.11e-01	-2.25e-02	9.43e-01
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding	84	7.22e-01	-2.24e-02	9.14e-01
GO:0050919 negative chemotaxis	22	8.57e-01	2.23e-02	9.52e-01
GO:0060391 positive regulation of SMAD protein signal transduction	13	8.91e-01	2.20e-02	9.63e-01
GO:0071356 cellular response to tumor necrosis factor	37	8.19e-01	-2.18e-02	9.43e-01
GO:0005634 nucleus	2130	1.11e-01	-2.16e-02	4.41e-01
GO:0006303 double-strand break repair via nonhomologous end joining	20	8.68e-01	2.15e-02	9.56e-01
GO:0004711 ribosomal protein S6 kinase activity	32	8.34e-01	-2.14e-02	9.47e-01
GO:0051301 cell division	144	6.58e-01	2.14e-02	8.96e-01
GO:0021915 neural tube development	17	8.80e-01	2.12e-02	9.59e-01
GO:0007519 skeletal muscle tissue development	16	8.83e-01	-2.12e-02	9.59e-01
GO:0032869 cellular response to insulin stimulus	33	8.34e-01	-2.11e-02	9.47e-01
GO:0045821 positive regulation of glycolytic process	10	9.10e-01	2.06e-02	9.70e-01
GO:0007173 epidermal growth factor receptor signaling pathway	38	8.26e-01	-2.06e-02	9.45e-01
GO:0050699 WW domain binding	11	9.06e-01	-2.05e-02	9.70e-01
GO:0016235 aggresome	17	8.85e-01	-2.03e-02	9.59e-01
GO:0007010 cytoskeleton organization	51	8.02e-01	2.03e-02	9.40e-01
GO:0043066 negative regulation of apoptotic process	151	6.69e-01	-2.02e-02	8.97e-01
GO:0003779 actin binding	141	6.81e-01	2.01e-02	9.01e-01
GO:0004879 nuclear receptor activity	38	8.31e-01	-2.01e-02	9.45e-01
GO:0045505 dynein intermediate chain binding	18	8.83e-01	2.00e-02	9.59e-01
GO:0072518 Rho-dependent protein serine/threonine kinase activity	32	8.45e-01	-1.99e-02	9.48e-01
GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity	34	8.41e-01	1.99e-02	9.48e-01
GO:0042060 wound healing	28	8.55e-01	1.99e-02	9.52e-01
GO:0035403 histone H3T6 kinase activity	32	8.47e-01	-1.97e-02	9.49e-01
GO:0004672 protein kinase activity	64	7.88e-01	1.95e-02	9.32e-01
GO:0050772 positive regulation of axonogenesis	13	9.04e-01	1.93e-02	9.68e-01
GO:0042802 identical protein binding	662	4.00e-01	1.93e-02	7.46e-01
GO:0001947 heart looping	22	8.76e-01	-1.92e-02	9.59e-01
GO:0005154 epidermal growth factor receptor binding	19	8.85e-01	1.92e-02	9.59e-01
GO:0001889 liver development	30	8.58e-01	-1.89e-02	9.53e-01
GO:0007219 Notch signaling pathway	42	8.32e-01	-1.89e-02	9.46e-01
GO:0008306 associative learning	11	9.14e-01	1.88e-02	9.70e-01
GO:0005737 cytoplasm	2175	1.63e-01	1.87e-02	5.13e-01
GO:0032154 cleavage furrow	28	8.64e-01	1.87e-02	9.56e-01
GO:0048013 ephrin receptor signaling pathway	24	8.74e-01	1.87e-02	9.59e-01
GO:0032465 regulation of cytokinesis	23	8.77e-01	1.87e-02	9.59e-01
GO:0030500 regulation of bone mineralization	12	9.11e-01	1.86e-02	9.70e-01
GO:0019706 protein-cysteine S-palmitoyltransferase activity	17	8.95e-01	1.85e-02	9.65e-01
GO:0010761 fibroblast migration	10	9.22e-01	-1.80e-02	9.74e-01
GO:0005667 transcription regulator complex	91	7.68e-01	-1.79e-02	9.28e-01
GO:0009897 external side of plasma membrane	108	7.48e-01	1.79e-02	9.21e-01
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway	12	9.15e-01	1.79e-02	9.70e-01
GO:0045444 fat cell differentiation	44	8.39e-01	1.77e-02	9.48e-01
GO:0051289 protein homotetramerization	35	8.56e-01	1.77e-02	9.52e-01
GO:0062023 collagen-containing extracellular matrix	73	7.98e-01	-1.74e-02	9.39e-01
GO:0043025 neuronal cell body	85	7.84e-01	-1.72e-02	9.29e-01
GO:0030544 Hsp70 protein binding	29	8.73e-01	1.72e-02	9.59e-01
GO:0042803 protein homodimerization activity	373	5.70e-01	1.72e-02	8.46e-01
GO:0001618 virus receptor activity	10	9.25e-01	-1.72e-02	9.74e-01
GO:0090398 cellular senescence	19	8.97e-01	-1.71e-02	9.66e-01
GO:0030336 negative regulation of cell migration	50	8.36e-01	-1.69e-02	9.48e-01
GO:0050714 positive regulation of protein secretion	19	9.00e-01	1.66e-02	9.66e-01
GO:0001503 ossification	26	8.85e-01	-1.64e-02	9.59e-01
GO:0007020 microtubule nucleation	14	9.16e-01	1.63e-02	9.70e-01
GO:0007613 memory	28	8.82e-01	-1.63e-02	9.59e-01
GO:0005911 cell-cell junction	78	8.05e-01	-1.61e-02	9.41e-01
GO:1990247 N6-methyladenosine-containing RNA reader activity	10	9.30e-01	-1.60e-02	9.78e-01
GO:0007032 endosome organization	28	8.85e-01	-1.58e-02	9.59e-01
GO:0090575 RNA polymerase II transcription regulator complex	53	8.42e-01	-1.58e-02	9.48e-01
GO:1990756 ubiquitin-like ligase-substrate adaptor activity	71	8.21e-01	-1.56e-02	9.43e-01
GO:0000242 pericentriolar material	14	9.20e-01	1.54e-02	9.74e-01
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	16	9.15e-01	1.54e-02	9.70e-01
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process	156	7.41e-01	1.54e-02	9.21e-01
GO:0030178 negative regulation of Wnt signaling pathway	17	9.14e-01	1.52e-02	9.70e-01
GO:0004676 3-phosphoinositide-dependent protein kinase activity	31	8.84e-01	-1.51e-02	9.59e-01
GO:0006417 regulation of translation	44	8.63e-01	-1.50e-02	9.56e-01
GO:0005666 RNA polymerase III complex	12	9.29e-01	-1.49e-02	9.77e-01
GO:0006270 DNA replication initiation	19	9.11e-01	-1.48e-02	9.70e-01
GO:0003756 protein disulfide isomerase activity	10	9.35e-01	1.48e-02	9.79e-01
GO:0043524 negative regulation of neuron apoptotic process	51	8.55e-01	-1.48e-02	9.52e-01
GO:0046627 negative regulation of insulin receptor signaling pathway	16	9.19e-01	-1.46e-02	9.73e-01
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity	19	9.13e-01	1.44e-02	9.70e-01
GO:0006289 nucleotide-excision repair	22	9.13e-01	1.35e-02	9.70e-01
GO:0070064 proline-rich region binding	10	9.42e-01	-1.34e-02	9.82e-01
GO:0030177 positive regulation of Wnt signaling pathway	17	9.24e-01	1.33e-02	9.74e-01
GO:0017148 negative regulation of translation	44	8.80e-01	1.31e-02	9.59e-01
GO:0007229 integrin-mediated signaling pathway	43	8.84e-01	-1.28e-02	9.59e-01
GO:0061608 nuclear import signal receptor activity	14	9.34e-01	1.28e-02	9.79e-01
GO:0065003 protein-containing complex assembly	37	8.93e-01	1.28e-02	9.64e-01
GO:0071526 semaphorin-plexin signaling pathway	24	9.14e-01	-1.27e-02	9.70e-01
GO:0007268 chemical synaptic transmission	32	9.02e-01	-1.26e-02	9.67e-01
GO:0030674 protein-macromolecule adaptor activity	73	8.53e-01	1.25e-02	9.52e-01
GO:0000166 nucleotide binding	37	8.95e-01	1.25e-02	9.65e-01
GO:0006631 fatty acid metabolic process	34	9.00e-01	1.25e-02	9.66e-01
GO:0098552 side of membrane	16	9.32e-01	1.23e-02	9.78e-01
GO:0030501 positive regulation of bone mineralization	14	9.37e-01	-1.22e-02	9.80e-01
GO:0050673 epithelial cell proliferation	20	9.25e-01	-1.22e-02	9.74e-01
GO:0032543 mitochondrial translation	22	9.22e-01	-1.21e-02	9.74e-01
GO:0043065 positive regulation of apoptotic process	121	8.21e-01	-1.20e-02	9.43e-01
GO:0000145 exocyst	11	9.45e-01	1.19e-02	9.84e-01
GO:0005080 protein kinase C binding	17	9.32e-01	1.19e-02	9.78e-01
GO:0032024 positive regulation of insulin secretion	21	9.25e-01	1.19e-02	9.74e-01
GO:0050870 positive regulation of T cell activation	14	9.40e-01	-1.15e-02	9.81e-01
GO:0036126 sperm flagellum	33	9.09e-01	1.15e-02	9.70e-01
GO:0005881 cytoplasmic microtubule	30	9.14e-01	1.13e-02	9.70e-01
GO:0050852 T cell receptor signaling pathway	50	8.91e-01	-1.12e-02	9.63e-01
GO:0033209 tumor necrosis factor-mediated signaling pathway	15	9.41e-01	-1.10e-02	9.82e-01
GO:0008340 determination of adult lifespan	21	9.31e-01	1.09e-02	9.78e-01
GO:0034063 stress granule assembly	21	9.33e-01	1.06e-02	9.78e-01
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity	20	9.35e-01	-1.05e-02	9.79e-01
GO:0045499 chemorepellent activity	19	9.37e-01	-1.04e-02	9.80e-01
GO:0055088 lipid homeostasis	19	9.39e-01	-1.02e-02	9.80e-01
GO:0016779 nucleotidyltransferase activity	11	9.55e-01	-9.91e-03	9.87e-01
GO:0030521 androgen receptor signaling pathway	12	9.53e-01	9.84e-03	9.87e-01
GO:0019902 phosphatase binding	23	9.35e-01	9.75e-03	9.79e-01
GO:0000902 cell morphogenesis	55	9.01e-01	-9.75e-03	9.66e-01
GO:0019005 SCF ubiquitin ligase complex	43	9.13e-01	-9.69e-03	9.70e-01
GO:0035024 negative regulation of Rho protein signal transduction	14	9.50e-01	9.66e-03	9.87e-01
GO:0005847 mRNA cleavage and polyadenylation specificity factor complex	11	9.56e-01	9.66e-03	9.87e-01
GO:0070936 protein K48-linked ubiquitination	68	8.91e-01	9.62e-03	9.63e-01
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator	11	9.57e-01	9.47e-03	9.87e-01
GO:1904047 S-adenosyl-L-methionine binding	13	9.54e-01	-9.29e-03	9.87e-01
GO:0009966 regulation of signal transduction	38	9.26e-01	8.72e-03	9.74e-01
GO:0048147 negative regulation of fibroblast proliferation	14	9.56e-01	-8.58e-03	9.87e-01
GO:0008253 5’-nucleotidase activity	10	9.63e-01	8.52e-03	9.90e-01
GO:0051082 unfolded protein binding	56	9.12e-01	8.50e-03	9.70e-01
GO:0051259 protein complex oligomerization	14	9.56e-01	-8.49e-03	9.87e-01
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading	25	9.43e-01	8.21e-03	9.82e-01
GO:0043022 ribosome binding	46	9.23e-01	8.20e-03	9.74e-01
GO:0016446 somatic hypermutation of immunoglobulin genes	10	9.64e-01	-8.17e-03	9.90e-01
GO:0007283 spermatogenesis	100	8.89e-01	-8.11e-03	9.62e-01
GO:0005506 iron ion binding	64	9.12e-01	7.98e-03	9.70e-01
GO:0016055 Wnt signaling pathway	78	9.05e-01	7.84e-03	9.69e-01
GO:0030890 positive regulation of B cell proliferation	21	9.51e-01	7.73e-03	9.87e-01
GO:0043231 intracellular membrane-bounded organelle	117	8.86e-01	7.68e-03	9.60e-01
GO:0006508 proteolysis	174	8.68e-01	7.35e-03	9.56e-01
GO:0030027 lamellipodium	91	9.07e-01	7.12e-03	9.70e-01
GO:0006367 transcription initiation at RNA polymerase II promoter	20	9.56e-01	-7.11e-03	9.87e-01
GO:1904263 positive regulation of TORC1 signaling	35	9.43e-01	-6.94e-03	9.82e-01
GO:0009749 response to glucose	14	9.66e-01	-6.65e-03	9.90e-01
GO:0045190 isotype switching	13	9.68e-01	6.39e-03	9.91e-01
GO:0006884 cell volume homeostasis	14	9.68e-01	-6.16e-03	9.91e-01
GO:0006376 mRNA splice site recognition	12	9.71e-01	6.07e-03	9.92e-01
GO:0016529 sarcoplasmic reticulum	14	9.69e-01	6.03e-03	9.91e-01
GO:0045599 negative regulation of fat cell differentiation	20	9.63e-01	-6.01e-03	9.90e-01
GO:0005657 replication fork	20	9.64e-01	5.85e-03	9.90e-01
GO:0001676 long-chain fatty acid metabolic process	11	9.73e-01	-5.83e-03	9.93e-01
GO:0034113 heterotypic cell-cell adhesion	11	9.73e-01	-5.80e-03	9.93e-01
GO:0019905 syntaxin binding	25	9.61e-01	-5.63e-03	9.89e-01
GO:0042742 defense response to bacterium	28	9.60e-01	-5.54e-03	9.89e-01
GO:0017025 TBP-class protein binding	18	9.68e-01	5.40e-03	9.91e-01
GO:0051085 chaperone cofactor-dependent protein refolding	23	9.65e-01	-5.32e-03	9.90e-01
GO:0031464 Cul4A-RING E3 ubiquitin ligase complex	10	9.77e-01	5.16e-03	9.95e-01
GO:0019722 calcium-mediated signaling	32	9.60e-01	-5.08e-03	9.89e-01
GO:1902600 proton transmembrane transport	59	9.48e-01	-4.90e-03	9.86e-01
GO:0000159 protein phosphatase type 2A complex	12	9.77e-01	-4.90e-03	9.95e-01
GO:0008286 insulin receptor signaling pathway	49	9.55e-01	-4.64e-03	9.87e-01
GO:0019900 kinase binding	49	9.56e-01	-4.57e-03	9.87e-01
GO:0004535 poly(A)-specific ribonuclease activity	10	9.80e-01	4.51e-03	9.95e-01
GO:0006606 protein import into nucleus	62	9.53e-01	-4.34e-03	9.87e-01
GO:0004725 protein tyrosine phosphatase activity	44	9.61e-01	4.30e-03	9.89e-01
GO:0019933 cAMP-mediated signaling	13	9.80e-01	3.97e-03	9.95e-01
GO:0005178 integrin binding	64	9.58e-01	3.78e-03	9.88e-01
GO:0003743 translation initiation factor activity	39	9.73e-01	3.17e-03	9.93e-01
GO:0008083 growth factor activity	41	9.73e-01	-3.08e-03	9.93e-01
GO:0004622 lysophospholipase activity	10	9.87e-01	3.06e-03	9.98e-01
GO:0007346 regulation of mitotic cell cycle	31	9.77e-01	2.95e-03	9.95e-01
GO:0016301 kinase activity	14	9.85e-01	-2.83e-03	9.98e-01
GO:0008203 cholesterol metabolic process	29	9.79e-01	-2.76e-03	9.95e-01
GO:0016251 RNA polymerase II general transcription initiation factor activity	22	9.84e-01	2.47e-03	9.97e-01
GO:0042734 presynaptic membrane	37	9.79e-01	2.47e-03	9.95e-01
GO:0051225 spindle assembly	21	9.87e-01	-2.01e-03	9.98e-01
GO:0071233 cellular response to L-leucine	10	9.91e-01	1.99e-03	9.98e-01
GO:0045211 postsynaptic membrane	59	9.79e-01	-1.95e-03	9.95e-01
GO:0005085 guanyl-nucleotide exchange factor activity	144	9.68e-01	1.94e-03	9.91e-01
GO:0005524 ATP binding	896	9.23e-01	1.93e-03	9.74e-01
GO:0038084 vascular endothelial growth factor signaling pathway	23	9.88e-01	-1.86e-03	9.98e-01
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	15	9.91e-01	1.77e-03	9.98e-01
GO:0000724 double-strand break repair via homologous recombination	71	9.81e-01	1.62e-03	9.95e-01
GO:0005868 cytoplasmic dynein complex	14	9.92e-01	-1.52e-03	9.98e-01
GO:0007204 positive regulation of cytosolic calcium ion concentration	18	9.92e-01	1.43e-03	9.98e-01
GO:0006874 intracellular calcium ion homeostasis	38	9.88e-01	1.41e-03	9.98e-01
GO:0008198 ferrous iron binding	12	9.93e-01	-1.37e-03	9.98e-01
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process	43	9.88e-01	-1.36e-03	9.98e-01
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity	16	9.93e-01	1.32e-03	9.98e-01
GO:0031124 mRNA 3’-end processing	13	9.95e-01	-9.34e-04	9.98e-01
GO:0031965 nuclear membrane	120	9.86e-01	-9.23e-04	9.98e-01
GO:0006260 DNA replication	34	9.93e-01	9.11e-04	9.98e-01
GO:0007275 multicellular organism development	26	9.94e-01	-8.18e-04	9.98e-01
GO:0036503 ERAD pathway	59	9.91e-01	8.07e-04	9.98e-01
GO:0003180 aortic valve morphogenesis	11	9.97e-01	6.40e-04	9.99e-01
GO:0045121 membrane raft	74	9.93e-01	5.75e-04	9.98e-01
GO:0010468 regulation of gene expression	58	9.95e-01	4.89e-04	9.98e-01
GO:0031398 positive regulation of protein ubiquitination	40	9.96e-01	-4.46e-04	9.98e-01
GO:0046966 nuclear thyroid hormone receptor binding	15	9.98e-01	4.14e-04	9.99e-01
GO:0008094 ATP-dependent activity, acting on DNA	11	9.99e-01	-2.01e-04	1.00e+00
GO:0051959 dynein light intermediate chain binding	17	1.00e+00	-5.69e-05	1.00e+00

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Detailed Gene set reports

GO:0000245 spliceosomal complex assembly

set	GO:0000245 spliceosomal complex assembly
setSize	10
pANOVA	6.52e-05
s.dist	-0.729
p.adjustANOVA	0.00862

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SCAF11	-6847
SRPK2	-6037
RBM10	-5987
SF3B1	-5675
PRPF19	-5642
ZRSR2	-5538
SRPK1	-5456
SF3A2	-4321
USP39	-4220
RSRP1	-4120

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SCAF11	-6847
SRPK2	-6037
RBM10	-5987
SF3B1	-5675
PRPF19	-5642
ZRSR2	-5538
SRPK1	-5456
SF3A2	-4321
USP39	-4220
RSRP1	-4120

---

GO:0022625 cytosolic large ribosomal subunit

set	GO:0022625 cytosolic large ribosomal subunit
setSize	40
pANOVA	1.17e-12
s.dist	0.649
p.adjustANOVA	1.93e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL13	6936
RPL9	6871
RPL3	6845
RPL35	6741
RPL7A	6728
RPL27	6693
RPL5	6600
RPL18A	6576
RPL37	6563
RPL27A	6473
RPL7	6417
RPL8	6337
RPL30	6270
RPL14	6219
RPL15	6046
RPLP1	5989
RPL34	5883
RPLP0	5869
RPL37A	5813
RPL7L1	5795

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL13	6936
RPL9	6871
RPL3	6845
RPL35	6741
RPL7A	6728
RPL27	6693
RPL5	6600
RPL18A	6576
RPL37	6563
RPL27A	6473
RPL7	6417
RPL8	6337
RPL30	6270
RPL14	6219
RPL15	6046
RPLP1	5989
RPL34	5883
RPLP0	5869
RPL37A	5813
RPL7L1	5795
RPL29	5678
RPL38	5647
RPL32	5611
RPL11	5599
RPLP2	5113
RPL26L1	5037
RPL35A	4677
RPL31	4539
RPL10A	4191
RPL6	3822
RPL19	3654
RPL23A	3614
RPL23	3441
RPL36	2409
RPL12	1764
RPL24	1502
RPL21	1154
RPL3L	-1670
RPL4	-4373
ZCCHC17	-5322

---

GO:0035145 exon-exon junction complex

set	GO:0035145 exon-exon junction complex
setSize	10
pANOVA	0.000412
s.dist	-0.645
p.adjustANOVA	0.0332

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SRSF1	-7287
UPF1	-7117
SMG6	-7009
PNN	-6993
UPF3B	-6164
TDRD3	-5448
UPF2	-3520
CASC3	-3308
UPF3A	-3250
THRAP3	2349

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SRSF1	-7287
UPF1	-7117
SMG6	-7009
PNN	-6993
UPF3B	-6164
TDRD3	-5448
UPF2	-3520
CASC3	-3308
UPF3A	-3250
THRAP3	2349

---

GO:0022627 cytosolic small ribosomal subunit

set	GO:0022627 cytosolic small ribosomal subunit
setSize	25
pANOVA	4.96e-07
s.dist	0.581
p.adjustANOVA	0.000293

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS2	7074
RPS15A	7032
RPS3A	7025
RPS4Y1	6997
RPS12	6949
RPS3	6751
RPS20	6530
RPS6	6510
RPS7	6446
RPS13	6427
RPS14	6286
RPS24	5968
RPS21	5952
RPS15	5744
RPS23	5568
RPS11	5489
RPS8	5427
RPS16	4139
EIF2A	2747
RPS27L	1427

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS2	7074
RPS15A	7032
RPS3A	7025
RPS4Y1	6997
RPS12	6949
RPS3	6751
RPS20	6530
RPS6	6510
RPS7	6446
RPS13	6427
RPS14	6286
RPS24	5968
RPS21	5952
RPS15	5744
RPS23	5568
RPS11	5489
RPS8	5427
RPS16	4139
EIF2A	2747
RPS27L	1427
RPS10	1068
RPS29	211
RPS26	-1933
RPS28	-6073
LARP4	-7182

---

GO:0030127 COPII vesicle coat

set	GO:0030127 COPII vesicle coat
setSize	10
pANOVA	0.00201
s.dist	0.564
p.adjustANOVA	0.089

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SEC24D	7047
SEC31A	6652
SEC23A	6640
PDCD6	5777
SAR1B	5406
PEF1	4378
SEC13	4025
SEC24B	3397
SEC24A	1583
SEC31B	-5046

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SEC24D	7047
SEC31A	6652
SEC23A	6640
PDCD6	5777
SAR1B	5406
PEF1	4378
SEC13	4025
SEC24B	3397
SEC24A	1583
SEC31B	-5046

---

GO:1905564 positive regulation of vascular endothelial cell proliferation

set	GO:1905564 positive regulation of vascular endothelial cell proliferation
setSize	10
pANOVA	0.00218
s.dist	0.56
p.adjustANOVA	0.0899

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ITGA4	7059
PLCG1	6772
PDPK1	6705
FGFR1	6392
NRARP	5013
SP1	4735
IGF2	2225
SIRT6	2145
AKT3	1008
STAT3	-2511

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ITGA4	7059
PLCG1	6772
PDPK1	6705
FGFR1	6392
NRARP	5013
SP1	4735
IGF2	2225
SIRT6	2145
AKT3	1008
STAT3	-2511

---

GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

set	GO:2001244 positive regulation of intrinsic apoptotic signaling pathway
setSize	11
pANOVA	0.00161
s.dist	0.549
p.adjustANOVA	0.0793

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CAV1	7010
BID	6670
RACK1	6552
DFNA5	5539
FLCN	4947
SLC9A3R1	4488
SIAH1	3994
PLEKHF1	3992
BCLAF1	3267
LCK	614
PLAGL2	-4420

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CAV1	7010
BID	6670
RACK1	6552
DFNA5	5539
FLCN	4947
SLC9A3R1	4488
SIAH1	3994
PLEKHF1	3992
BCLAF1	3267
LCK	614
PLAGL2	-4420

---

GO:1903076 regulation of protein localization to plasma membrane

set	GO:1903076 regulation of protein localization to plasma membrane
setSize	18
pANOVA	6.63e-05
s.dist	0.543
p.adjustANOVA	0.00862

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SDC4	7136
VPS4A	6905
VTI1B	6398
STX7	6275
AR	6025
ZDHHC7	5919
LDLRAP1	5810
CAMK2D	5769
CAMK2A	5640
MAPKAPK3	4900
EPM2A	4079
CAMK2G	3603
STX8	3485
SIRT6	2145
ZDHHC2	1956
PIK3R1	1944
NHLRC1	-3637
PIK3R2	-5379

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SDC4	7136
VPS4A	6905
VTI1B	6398
STX7	6275
AR	6025
ZDHHC7	5919
LDLRAP1	5810
CAMK2D	5769
CAMK2A	5640
MAPKAPK3	4900
EPM2A	4079
CAMK2G	3603
STX8	3485
SIRT6	2145
ZDHHC2	1956
PIK3R1	1944
NHLRC1	-3637
PIK3R2	-5379

---

GO:0002181 cytoplasmic translation

set	GO:0002181 cytoplasmic translation
setSize	27
pANOVA	1.69e-06
s.dist	0.532
p.adjustANOVA	0.000631

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL9	6871
RPL18A	6576
RPS6	6510
RPL8	6337
RPS14	6286
RPL15	6046
RPL22	6030
RPLP1	5989
RPLP0	5869
RPL29	5678
RPL38	5647
RPS23	5568
DRG2	5521
RPL26L1	5037
RPL35A	4677
RPL31	4539
RPL10A	4191
RPL22L1	4175
RPL6	3822
SARS1	2646

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL9	6871
RPL18A	6576
RPS6	6510
RPL8	6337
RPS14	6286
RPL15	6046
RPL22	6030
RPLP1	5989
RPLP0	5869
RPL29	5678
RPL38	5647
RPS23	5568
DRG2	5521
RPL26L1	5037
RPL35A	4677
RPL31	4539
RPL10A	4191
RPL22L1	4175
RPL6	3822
SARS1	2646
RPL36	2409
RPL24	1502
RPS29	211
RWDD1	104
RPS26	-1933
ZC3H15	-2950
RPS28	-6073

---

GO:1903077 negative regulation of protein localization to plasma membrane

set	GO:1903077 negative regulation of protein localization to plasma membrane
setSize	13
pANOVA	0.00102
s.dist	0.526
p.adjustANOVA	0.0622

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PID1	7079
TMED2	6537
DAB2	6303
PPP2R5A	6012
PICALM	5598
NUMB	4650
TMBIM1	4635
PPFIA1	4373
LYPD1	4081
TMEM59	3378
CLTC	2356
RHOQ	345
LRRC15	-7103

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PID1	7079
TMED2	6537
DAB2	6303
PPP2R5A	6012
PICALM	5598
NUMB	4650
TMBIM1	4635
PPFIA1	4373
LYPD1	4081
TMEM59	3378
CLTC	2356
RHOQ	345
LRRC15	-7103

---

GO:0004364 glutathione transferase activity

set	GO:0004364 glutathione transferase activity
setSize	10
pANOVA	0.00573
s.dist	0.505
p.adjustANOVA	0.141

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HPGDS	6995
GSTO2	6673
MGST3	5773
GSTT1	5648
MGST1	5249
GSTZ1	5096
GSTM2	2414
PTGES	2219
GSTK1	1650
LANCL1	-6166

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HPGDS	6995
GSTO2	6673
MGST3	5773
GSTT1	5648
MGST1	5249
GSTZ1	5096
GSTM2	2414
PTGES	2219
GSTK1	1650
LANCL1	-6166

---

GO:0004602 glutathione peroxidase activity

set	GO:0004602 glutathione peroxidase activity
setSize	12
pANOVA	0.00253
s.dist	0.503
p.adjustANOVA	0.0974

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CLIC2	7026
GPX3	6724
GPX7	6529
MGST3	5773
PRDX6	5743
CP	5685
MGST1	5249
PTGES	2219
GSTK1	1650
GPX8	-219
GPX4	-371
GPX1	-3452

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CLIC2	7026
GPX3	6724
GPX7	6529
MGST3	5773
PRDX6	5743
CP	5685
MGST1	5249
PTGES	2219
GSTK1	1650
GPX8	-219
GPX4	-371
GPX1	-3452

---

GO:0071353 cellular response to interleukin-4

set	GO:0071353 cellular response to interleukin-4
setSize	10
pANOVA	0.00592
s.dist	0.503
p.adjustANOVA	0.141

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL3	6845
HSPA5	6154
MCM2	6084
RPLP0	5869
IMPDH2	4431
SHPK	4080
NFIL3	2473
FASN	2338
LEF1	-1237
TCF7	-1631

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL3	6845
HSPA5	6154
MCM2	6084
RPLP0	5869
IMPDH2	4431
SHPK	4080
NFIL3	2473
FASN	2338
LEF1	-1237
TCF7	-1631

---

GO:0004683 calcium/calmodulin-dependent protein kinase activity

set	GO:0004683 calcium/calmodulin-dependent protein kinase activity
setSize	11
pANOVA	0.0056
s.dist	0.482
p.adjustANOVA	0.141

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MAPKAPK2	7090
CAMK2D	5769
CAMK2A	5640
MAPKAPK3	4900
MYLK3	4646
CAMK2G	3603
MAPKAPK5	2834
MKNK2	2766
CAMK1	1360
CAMK1G	-430
DAPK1	-841

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MAPKAPK2	7090
CAMK2D	5769
CAMK2A	5640
MAPKAPK3	4900
MYLK3	4646
CAMK2G	3603
MAPKAPK5	2834
MKNK2	2766
CAMK1	1360
CAMK1G	-430
DAPK1	-841

---

GO:0044322 endoplasmic reticulum quality control compartment

set	GO:0044322 endoplasmic reticulum quality control compartment
setSize	11
pANOVA	0.00584
s.dist	0.48
p.adjustANOVA	0.141

Top enriched genes

Top 20 genes

GeneID	Gene Rank
DERL1	6803
ERN2	6657
HERPUD1	6518
SEC61B	6218
CANX	5735
EDEM3	3835
EDEM1	3022
SYVN1	1722
MAN1B1	-939
RHBDD1	-1194
EDEM2	-1231

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
DERL1	6803
ERN2	6657
HERPUD1	6518
SEC61B	6218
CANX	5735
EDEM3	3835
EDEM1	3022
SYVN1	1722
MAN1B1	-939
RHBDD1	-1194
EDEM2	-1231

---

GO:0051642 centrosome localization

set	GO:0051642 centrosome localization
setSize	14
pANOVA	0.00191
s.dist	0.479
p.adjustANOVA	0.0865

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SUN1	7104
DLGAP5	6864
CCDC141	6583
SUN2	6386
NUBP1	6375
NDE1	5659
NIN	4871
PLXNA2	4524
IFT20	3135
NDEL1	2872
SYNE2	233
BICD2	-144
INTS13	-2327
KIF5B	-4950

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SUN1	7104
DLGAP5	6864
CCDC141	6583
SUN2	6386
NUBP1	6375
NDE1	5659
NIN	4871
PLXNA2	4524
IFT20	3135
NDEL1	2872
SYNE2	233
BICD2	-144
INTS13	-2327
KIF5B	-4950

---

GO:0007017 microtubule-based process

set	GO:0007017 microtubule-based process
setSize	11
pANOVA	0.00597
s.dist	0.479
p.adjustANOVA	0.141

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KIF25	6956
DYL1	6574
DCTN3	6258
DNAL4	6000
TUBD1	4777
TUBB4B	4418
TUBA1A	3640
TUBA8A	2610
TUBE1	1383
TUBB6	219
DYNLL2	-5793

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KIF25	6956
DYL1	6574
DCTN3	6258
DNAL4	6000
TUBD1	4777
TUBB4B	4418
TUBA1A	3640
TUBA8A	2610
TUBE1	1383
TUBB6	219
DYNLL2	-5793

---

GO:0030020 extracellular matrix structural constituent conferring tensile strength

set	GO:0030020 extracellular matrix structural constituent conferring tensile strength
setSize	16
pANOVA	0.001
s.dist	0.475
p.adjustANOVA	0.0622

Top enriched genes

Top 20 genes

GeneID	Gene Rank
COL8A1	7149
COL5A2	7131
COL3A1	7128
COL18A1	7126
COL11A1	7071
COL16A1	6733
COL1A1	6671
COL1A2	6435
COL5A1	6277
COL6A1	5375
EMID1	485
COL9A2	-682
COLQ	-1709
COL17A1	-2121
COL4A6	-4222
COL26A1	-5399

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
COL8A1	7149
COL5A2	7131
COL3A1	7128
COL18A1	7126
COL11A1	7071
COL16A1	6733
COL1A1	6671
COL1A2	6435
COL5A1	6277
COL6A1	5375
EMID1	485
COL9A2	-682
COLQ	-1709
COL17A1	-2121
COL4A6	-4222
COL26A1	-5399

---

GO:0030100 regulation of endocytosis

set	GO:0030100 regulation of endocytosis
setSize	12
pANOVA	0.00477
s.dist	0.471
p.adjustANOVA	0.132

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RUFY1	6078
RAB4A	5892
RAB14	5759
PACSIN2	4988
OPHN1	4729
PTPN1	4701
BIN1	4560
PACSIN3	3540
ARFGAP1	3489
HIP1R	2237
SNX12	-147
STON2	-6130

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RUFY1	6078
RAB4A	5892
RAB14	5759
PACSIN2	4988
OPHN1	4729
PTPN1	4701
BIN1	4560
PACSIN3	3540
ARFGAP1	3489
HIP1R	2237
SNX12	-147
STON2	-6130

---

GO:0008593 regulation of Notch signaling pathway

set	GO:0008593 regulation of Notch signaling pathway
setSize	10
pANOVA	0.0117
s.dist	0.46
p.adjustANOVA	0.179

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LLGL2	6409
POFUT1	6407
LFNG	6227
LLGL1	6077
RFNG	5423
ADAM10	4894
GALNT11	4138
TSPEAR	593
PRAG1	-543
POSTN	-7286

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LLGL2	6409
POFUT1	6407
LFNG	6227
LLGL1	6077
RFNG	5423
ADAM10	4894
GALNT11	4138
TSPEAR	593
PRAG1	-543
POSTN	-7286

---

GO:0140662 ATP-dependent protein folding chaperone

set	GO:0140662 ATP-dependent protein folding chaperone
setSize	23
pANOVA	0.000149
s.dist	-0.457
p.adjustANOVA	0.0163

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HSPA8	-7184
CLPX	-7139
HSP90B1	-7119
HSP90AA1	-6962
HSPH1	-6901
HSPA4	-6704
TOR1A	-6547
HSPA13	-6497
CCT2	-6217
HYOU1	-6126
HSPA14	-5959
HSPD1	-4931
TCP1	-4333
CCT3	-3545
CCT7	-3506
CCT8	-2714
CCT5	-1723
HSPA4L	-280
CCT4	-43
HSPA9	137

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HSPA8	-7184
CLPX	-7139
HSP90B1	-7119
HSP90AA1	-6962
HSPH1	-6901
HSPA4	-6704
TOR1A	-6547
HSPA13	-6497
CCT2	-6217
HYOU1	-6126
HSPA14	-5959
HSPD1	-4931
TCP1	-4333
CCT3	-3545
CCT7	-3506
CCT8	-2714
CCT5	-1723
HSPA4L	-280
CCT4	-43
HSPA9	137
HSPA2	2972
HSPA5	6154
TRAP1	6763

---

GO:0035925 mRNA 3’-UTR AU-rich region binding

set	GO:0035925 mRNA 3’-UTR AU-rich region binding
setSize	13
pANOVA	0.00461
s.dist	0.454
p.adjustANOVA	0.132

Top enriched genes

Top 20 genes

GeneID	Gene Rank
EXOSC9	5848
RBMS3	5387
FXR1	4985
MEX3D	4964
TIA1	4714
ZFP36L2	4419
NUDT21	4241
ELAVL1	3138
DHX36	2998
ZC3H12A	2464
ARID5A	1408
EXOSC7	84
EXOSC8	-3225

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
EXOSC9	5848
RBMS3	5387
FXR1	4985
MEX3D	4964
TIA1	4714
ZFP36L2	4419
NUDT21	4241
ELAVL1	3138
DHX36	2998
ZC3H12A	2464
ARID5A	1408
EXOSC7	84
EXOSC8	-3225

---

GO:0090110 COPII-coated vesicle cargo loading

set	GO:0090110 COPII-coated vesicle cargo loading
setSize	10
pANOVA	0.0133
s.dist	0.452
p.adjustANOVA	0.193

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SEC24D	7047
SEC31A	6652
SEC23A	6640
SAR1B	5406
SURF4	5369
SEC13	4025
SEC24B	3397
SEC24A	1583
TBC1D20	-3310
SEC31B	-5046

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SEC24D	7047
SEC31A	6652
SEC23A	6640
SAR1B	5406
SURF4	5369
SEC13	4025
SEC24B	3397
SEC24A	1583
TBC1D20	-3310
SEC31B	-5046

---

GO:0005791 rough endoplasmic reticulum

set	GO:0005791 rough endoplasmic reticulum
setSize	12
pANOVA	0.00786
s.dist	-0.443
p.adjustANOVA	0.163

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TMCC1	-6689
PKLR	-6524
PSEN1	-6406
CDKAL1	-6129
SUCO	-6034
MYOC	-4625
RPL4	-4373
PLOD2	-4141
SPPL3	-1991
HM13	-1658
LRAT	2139
RPL27	6693

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TMCC1	-6689
PKLR	-6524
PSEN1	-6406
CDKAL1	-6129
SUCO	-6034
MYOC	-4625
RPL4	-4373
PLOD2	-4141
SPPL3	-1991
HM13	-1658
LRAT	2139
RPL27	6693

---

GO:0044458 motile cilium assembly

set	GO:0044458 motile cilium assembly
setSize	12
pANOVA	0.00793
s.dist	0.443
p.adjustANOVA	0.163

Top enriched genes

Top 20 genes

GeneID	Gene Rank
DYL1	6574
DNAAF1	6447
SPATA6	5915
ATMIN	5356
INTU	5157
RSPH9	5119
CC2D2A	4425
CENPJ	2757
LRRC6	1713
IFT57	-349
CCDC40	-2351
FOXJ1	-3491

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
DYL1	6574
DNAAF1	6447
SPATA6	5915
ATMIN	5356
INTU	5157
RSPH9	5119
CC2D2A	4425
CENPJ	2757
LRRC6	1713
IFT57	-349
CCDC40	-2351
FOXJ1	-3491

---

GO:1902774 late endosome to lysosome transport

set	GO:1902774 late endosome to lysosome transport
setSize	10
pANOVA	0.0156
s.dist	0.442
p.adjustANOVA	0.206

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CHMP4C	7068
VPS39	6183
CHMP2B	6007
C9orf72	4550
CHMP1B	4219
CHMP5	3668
VPS41	2385
CHMP7	2284
CHMP3	1721
CHMP2A	-7090

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CHMP4C	7068
VPS39	6183
CHMP2B	6007
C9orf72	4550
CHMP1B	4219
CHMP5	3668
VPS41	2385
CHMP7	2284
CHMP3	1721
CHMP2A	-7090

---

GO:0030863 cortical cytoskeleton

set	GO:0030863 cortical cytoskeleton
setSize	10
pANOVA	0.0171
s.dist	0.435
p.adjustANOVA	0.221

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GYPC	6624
NOS2	6261
CTTN	6001
EPB41	5975
MPP1	5706
DMTN	5650
CAPZA2	4572
CAPZA1	-78
TPM4	-3877
CAPZB	-6299

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GYPC	6624
NOS2	6261
CTTN	6001
EPB41	5975
MPP1	5706
DMTN	5650
CAPZA2	4572
CAPZA1	-78
TPM4	-3877
CAPZB	-6299

---

GO:0030992 intraciliary transport particle B

set	GO:0030992 intraciliary transport particle B
setSize	15
pANOVA	0.00392
s.dist	0.43
p.adjustANOVA	0.125

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IFT27	6551
TRIM59	6129
IFT52	5930
HSPB11	5429
IFT80	5221
TRAF3IP1	4832
IFT46	3888
IFT20	3135
IFT74	2379
IFT81	1709
IFT172	1165
IFT22	979
IFT88	679
IFT57	-349
UBXN10	-2447

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IFT27	6551
TRIM59	6129
IFT52	5930
HSPB11	5429
IFT80	5221
TRAF3IP1	4832
IFT46	3888
IFT20	3135
IFT74	2379
IFT81	1709
IFT172	1165
IFT22	979
IFT88	679
IFT57	-349
UBXN10	-2447

---

GO:0043995 histone H4K5 acetyltransferase activity

set	GO:0043995 histone H4K5 acetyltransferase activity
setSize	10
pANOVA	0.0198
s.dist	-0.425
p.adjustANOVA	0.23

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BRPF1	-6837
JADE1	-5080
HAT1	-4772
BRPF3	-4709
KAT8	-4513
ING4	-4340
KAT6A	-3997
ING3	-672
MEAF6	1114
KAT7	1974

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BRPF1	-6837
JADE1	-5080
HAT1	-4772
BRPF3	-4709
KAT8	-4513
ING4	-4340
KAT6A	-3997
ING3	-672
MEAF6	1114
KAT7	1974

---

GO:0043996 histone H4K8 acetyltransferase activity

set	GO:0043996 histone H4K8 acetyltransferase activity
setSize	10
pANOVA	0.0198
s.dist	-0.425
p.adjustANOVA	0.23

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BRPF1	-6837
JADE1	-5080
HAT1	-4772
BRPF3	-4709
KAT8	-4513
ING4	-4340
KAT6A	-3997
ING3	-672
MEAF6	1114
KAT7	1974

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BRPF1	-6837
JADE1	-5080
HAT1	-4772
BRPF3	-4709
KAT8	-4513
ING4	-4340
KAT6A	-3997
ING3	-672
MEAF6	1114
KAT7	1974

---

GO:0001772 immunological synapse

set	GO:0001772 immunological synapse
setSize	22
pANOVA	0.00059
s.dist	0.423
p.adjustANOVA	0.0402

Top enriched genes

Top 20 genes

GeneID	Gene Rank
EZR	7086
CARD11	7083
CD81	6799
STX7	6275
CD3E	6204
CRTAM	6058
ARHGDIA	6027
PRKAR1A	5766
SKAP1	5546
LGALS3	5487
MYH9	5452
ATP2B1	5133
SCRIB	5090
VAV3	3525
NEDD9	3245
LCK	614
SOCS6	312
CARD10	-922
NPTN	-3698
STOML2	-4128

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
EZR	7086
CARD11	7083
CD81	6799
STX7	6275
CD3E	6204
CRTAM	6058
ARHGDIA	6027
PRKAR1A	5766
SKAP1	5546
LGALS3	5487
MYH9	5452
ATP2B1	5133
SCRIB	5090
VAV3	3525
NEDD9	3245
LCK	614
SOCS6	312
CARD10	-922
NPTN	-3698
STOML2	-4128
SNX27	-5076
DLG1	-6693

---

GO:0043997 histone H4K12 acetyltransferase activity

set	GO:0043997 histone H4K12 acetyltransferase activity
setSize	10
pANOVA	0.0207
s.dist	-0.422
p.adjustANOVA	0.232

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BRPF1	-6837
JADE1	-5080
HAT1	-4772
BRPF3	-4709
ING4	-4340
KAT2A	-4301
KAT6A	-3997
ING3	-672
MEAF6	1114
KAT7	1974

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BRPF1	-6837
JADE1	-5080
HAT1	-4772
BRPF3	-4709
ING4	-4340
KAT2A	-4301
KAT6A	-3997
ING3	-672
MEAF6	1114
KAT7	1974

---

GO:0061952 midbody abscission

set	GO:0061952 midbody abscission
setSize	14
pANOVA	0.00755
s.dist	0.412
p.adjustANOVA	0.163

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CHMP4C	7068
VPS4A	6905
CHMP2B	6007
ZFYVE19	5512
KIF20A	5475
CHMP1B	4219
MTMR3	3764
CHMP5	3668
MITD1	2969
IST1	2345
CHMP7	2284
CHMP3	1721
VPS4B	-4438
CHMP2A	-7090

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CHMP4C	7068
VPS4A	6905
CHMP2B	6007
ZFYVE19	5512
KIF20A	5475
CHMP1B	4219
MTMR3	3764
CHMP5	3668
MITD1	2969
IST1	2345
CHMP7	2284
CHMP3	1721
VPS4B	-4438
CHMP2A	-7090

---

GO:0048018 receptor ligand activity

set	GO:0048018 receptor ligand activity
setSize	18
pANOVA	0.00246
s.dist	-0.412
p.adjustANOVA	0.0966

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GPNMB	-7280
HSPA8	-7184
GREM2	-7143
NBL1	-7106
SEMA4D	-6997
FN1	-6972
IGFBP5	-6868
EDA	-6202
NRG4	-4456
RELN	-4160
ANGPT1	-3089
IGFBP7	-2964
WNT8B	-731
CLU	1083
F2RL2	3029
DLL4	3154
LRPAP1	3233
APP	5081

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GPNMB	-7280
HSPA8	-7184
GREM2	-7143
NBL1	-7106
SEMA4D	-6997
FN1	-6972
IGFBP5	-6868
EDA	-6202
NRG4	-4456
RELN	-4160
ANGPT1	-3089
IGFBP7	-2964
WNT8B	-731
CLU	1083
F2RL2	3029
DLL4	3154
LRPAP1	3233
APP	5081

---

GO:0003724 RNA helicase activity

set	GO:0003724 RNA helicase activity
setSize	37
pANOVA	1.49e-05
s.dist	-0.411
p.adjustANOVA	0.0033

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UPF1	-7117
DDX3X	-6961
DDX18	-6787
DDX54	-6520
DDX24	-6517
EIF4A2	-6252
DDX46	-6249
DDX41	-6196
SUPV3L1	-5993
DDX25	-5847
DDX49	-5759
DDX52	-5690
DDX6	-5042
IFIH1	-4918
DHX15	-4616
DDX42	-4497
DHX30	-4278
DHX58	-4125
SNRNP200	-4023
DDX19	-3919

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UPF1	-7117
DDX3X	-6961
DDX18	-6787
DDX54	-6520
DDX24	-6517
EIF4A2	-6252
DDX46	-6249
DDX41	-6196
SUPV3L1	-5993
DDX25	-5847
DDX49	-5759
DDX52	-5690
DDX6	-5042
IFIH1	-4918
DHX15	-4616
DDX42	-4497
DHX30	-4278
DHX58	-4125
SNRNP200	-4023
DDX19	-3919
DHX8	-3821
FANCM	-3701
SKIV2L2	-3476
DDX59	-3234
DDX47	-3191
DDX20	-1919
EIF4A3	-871
DDX28	-859
G3BP1	-231
DHX29	-87
DDX55	68
DDX1	1257
DDX5	2209
DHX36	2998
DDX17	3275
DDX27	4441
DDX10	4617

---

GO:0070182 DNA polymerase binding

set	GO:0070182 DNA polymerase binding
setSize	13
pANOVA	0.0103
s.dist	-0.411
p.adjustANOVA	0.179

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RTEL1	-7074
SMG6	-7009
HSP90AA1	-6962
FANCI	-6936
NAT10	-6308
FANCD2	-6155
NABP2	-5969
SMARCA4	-4232
PTGES3	-1520
LONP1	1942
NHEJ1	2386
PCNA	3435
POLG2	4366

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RTEL1	-7074
SMG6	-7009
HSP90AA1	-6962
FANCI	-6936
NAT10	-6308
FANCD2	-6155
NABP2	-5969
SMARCA4	-4232
PTGES3	-1520
LONP1	1942
NHEJ1	2386
PCNA	3435
POLG2	4366

---

GO:0060395 SMAD protein signal transduction

set	GO:0060395 SMAD protein signal transduction
setSize	14
pANOVA	0.00829
s.dist	-0.408
p.adjustANOVA	0.169

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FOS	-7319
RBPMS	-7217
SMAD3	-7186
SMAD5	-6905
ZMIZ1	-6865
SMAD6	-6228
HIPK2	-4720
JUN	-4527
SMAD7B	-2713
SMAD1	-756
WWTR1	1597
SMAD2	2273
RUNX2	3347
SMAD9	4477

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FOS	-7319
RBPMS	-7217
SMAD3	-7186
SMAD5	-6905
ZMIZ1	-6865
SMAD6	-6228
HIPK2	-4720
JUN	-4527
SMAD7B	-2713
SMAD1	-756
WWTR1	1597
SMAD2	2273
RUNX2	3347
SMAD9	4477

---

GO:0040029 epigenetic regulation of gene expression

set	GO:0040029 epigenetic regulation of gene expression
setSize	18
pANOVA	0.00279
s.dist	-0.407
p.adjustANOVA	0.103

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HDAC7	-7284
KDM1A	-6627
EHMT1	-6561
MTF2	-5965
ZNF335	-5540
CGGBP1	-4994
RNF8	-4593
MSL2	-4427
HDAC3	-4389
HDAC4	-4121
GPX1	-3452
RNF168	-3029
GLMN	-2905
METTL23	-929
KMT2E	363
RNF2	1388
HDAC10	2694
SIRT2	5488

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HDAC7	-7284
KDM1A	-6627
EHMT1	-6561
MTF2	-5965
ZNF335	-5540
CGGBP1	-4994
RNF8	-4593
MSL2	-4427
HDAC3	-4389
HDAC4	-4121
GPX1	-3452
RNF168	-3029
GLMN	-2905
METTL23	-929
KMT2E	363
RNF2	1388
HDAC10	2694
SIRT2	5488

---

GO:0032968 positive regulation of transcription elongation by RNA polymerase II

set	GO:0032968 positive regulation of transcription elongation by RNA polymerase II
setSize	15
pANOVA	0.00645
s.dist	-0.406
p.adjustANOVA	0.15

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CDK13	-7216
LEO1	-7206
SUPT6H	-6593
PWWP2B	-6131
CTNNB1	-5669
CDK12	-5022
OCLN	-4710
PWWP2A	-4304
CCNT1	-4295
ELL	-2553
ELL2	-1860
CDK9	1043
ZMYND8	1073
CDC73	3322
EAPP	4468

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CDK13	-7216
LEO1	-7206
SUPT6H	-6593
PWWP2B	-6131
CTNNB1	-5669
CDK12	-5022
OCLN	-4710
PWWP2A	-4304
CCNT1	-4295
ELL	-2553
ELL2	-1860
CDK9	1043
ZMYND8	1073
CDC73	3322
EAPP	4468

---

GO:0005852 eukaryotic translation initiation factor 3 complex

set	GO:0005852 eukaryotic translation initiation factor 3 complex
setSize	10
pANOVA	0.0267
s.dist	0.405
p.adjustANOVA	0.264

Top enriched genes

Top 20 genes

GeneID	Gene Rank
EIF3H	6669
EIF3E	6441
EIF3B	6107
EIF3K	5782
EIF3D	4533
EIF3G	3893
EIF3L	3438
EIF3M	507
EIF3F	-1741
EIF3J	-7308

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
EIF3H	6669
EIF3E	6441
EIF3B	6107
EIF3K	5782
EIF3D	4533
EIF3G	3893
EIF3L	3438
EIF3M	507
EIF3F	-1741
EIF3J	-7308

---

GO:0048041 focal adhesion assembly

set	GO:0048041 focal adhesion assembly
setSize	14
pANOVA	0.00882
s.dist	-0.404
p.adjustANOVA	0.171

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PTPRK	-7003
FN1	-6972
PEAK1	-6897
PIP5K1A	-6822
WHAMM	-6525
RCC2	-4494
FERMT2	-4204
THY1	-3279
CDH11	-3201
SRC	-2747
BCR	-1589
BCL2	117
CORO2B	4059
ARHGAP6	7143

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PTPRK	-7003
FN1	-6972
PEAK1	-6897
PIP5K1A	-6822
WHAMM	-6525
RCC2	-4494
FERMT2	-4204
THY1	-3279
CDH11	-3201
SRC	-2747
BCR	-1589
BCL2	117
CORO2B	4059
ARHGAP6	7143

---

GO:0051010 microtubule plus-end binding

set	GO:0051010 microtubule plus-end binding
setSize	11
pANOVA	0.0203
s.dist	0.404
p.adjustANOVA	0.231

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PAFAH1B1	6114
MAPRE1	5925
KIF18A	5644
KIF2C	5641
CLIP1	5462
CKAP5	5447
CLIP2	4669
MAPRE2	1936
MAPRE3	-192
FBXW11	-2670
NUMA1	-6880

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PAFAH1B1	6114
MAPRE1	5925
KIF18A	5644
KIF2C	5641
CLIP1	5462
CKAP5	5447
CLIP2	4669
MAPRE2	1936
MAPRE3	-192
FBXW11	-2670
NUMA1	-6880

---

GO:0005544 calcium-dependent phospholipid binding

set	GO:0005544 calcium-dependent phospholipid binding
setSize	21
pANOVA	0.0014
s.dist	0.403
p.adjustANOVA	0.0761

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ANXA1	7113
CPNE1	6980
ANXA6	6837
SYT17	6476
CPNE2	6305
ANXA5	6295
ANXA11	5780
ESYT1	5652
CPNE3	5589
C2CD5	5244
ESYT2	4759
ANXA13	4305
CPNE8	2434
SYT13	1918
SYT12	1052
ANXA2	1027
SYT11	428
CPNE9	-1643
ANXA7	-4352
DYSF	-6110

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ANXA1	7113
CPNE1	6980
ANXA6	6837
SYT17	6476
CPNE2	6305
ANXA5	6295
ANXA11	5780
ESYT1	5652
CPNE3	5589
C2CD5	5244
ESYT2	4759
ANXA13	4305
CPNE8	2434
SYT13	1918
SYT12	1052
ANXA2	1027
SYT11	428
CPNE9	-1643
ANXA7	-4352
DYSF	-6110
PLA2G4A	-6987

---

GO:0017056 structural constituent of nuclear pore

set	GO:0017056 structural constituent of nuclear pore
setSize	19
pANOVA	0.00267
s.dist	-0.398
p.adjustANOVA	0.101

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NUP188	-6877
TPR	-6639
NUP153	-6548
NUP35	-6420
NUP214	-6187
NUP98	-6052
NUP54	-5707
NUP133	-5327
NDC1	-5248
NUP155	-4963
NUP205	-4485
NUP160	-3954
NUP107	-2019
NUP58	-1571
NUP85	-1388
NUP88	1290
NUP62	2909
NUP93	5740
NUTF2	6766

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NUP188	-6877
TPR	-6639
NUP153	-6548
NUP35	-6420
NUP214	-6187
NUP98	-6052
NUP54	-5707
NUP133	-5327
NDC1	-5248
NUP155	-4963
NUP205	-4485
NUP160	-3954
NUP107	-2019
NUP58	-1571
NUP85	-1388
NUP88	1290
NUP62	2909
NUP93	5740
NUTF2	6766

---

GO:0098869 cellular oxidant detoxification

set	GO:0098869 cellular oxidant detoxification
setSize	28
pANOVA	0.00032
s.dist	0.393
p.adjustANOVA	0.0284

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GPX3	6724
GSTO2	6673
TXNRD3	6625
GPX7	6529
PXDN	6469
MGST3	5773
PRDX6	5743
CP	5685
TXNRD1	5637
MGST1	5249
PRDX4	4925
TP53INP1	4532
SELENOT	4107
SESN1	2769
SRXN1	2309
SESN2	2265
TXNRD2	2258
PTGES	2219
GSR	1772
GSTK1	1650

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GPX3	6724
GSTO2	6673
TXNRD3	6625
GPX7	6529
PXDN	6469
MGST3	5773
PRDX6	5743
CP	5685
TXNRD1	5637
MGST1	5249
PRDX4	4925
TP53INP1	4532
SELENOT	4107
SESN1	2769
SRXN1	2309
SESN2	2265
TXNRD2	2258
PTGES	2219
GSR	1772
GSTK1	1650
NXN	-76
GPX8	-219
PRXL2A	-336
GPX4	-371
SELENOW	-373
GPX1	-3452
PRDX3	-3798
EPX	-4500

---

GO:0032924 activin receptor signaling pathway

set	GO:0032924 activin receptor signaling pathway
setSize	12
pANOVA	0.0189
s.dist	-0.391
p.adjustANOVA	0.225

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SMAD3	-7186
TGFBR2	-6974
INHBA	-6061
ACVR2A	-5894
BMPR1A	-5714
INHBB	-4686
GDF11	-2288
ATVR1	-1954
BMPR2	186
ACVR2B	1451
ACVR1C	1614
SMAD2	2273

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SMAD3	-7186
TGFBR2	-6974
INHBA	-6061
ACVR2A	-5894
BMPR1A	-5714
INHBB	-4686
GDF11	-2288
ATVR1	-1954
BMPR2	186
ACVR2B	1451
ACVR1C	1614
SMAD2	2273

---

GO:0090128 regulation of synapse maturation

set	GO:0090128 regulation of synapse maturation
setSize	11
pANOVA	0.0261
s.dist	0.387
p.adjustANOVA	0.262

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CLSTN1	7105
YWHAZ	6753
VPS35	6719
DLGAP4	5771
CNTNAP1	5764
DISC1	4967
ROCK1	2157
AGO2	712
NEFL	-1526
SEMA7A	-3577
SNX27	-5076

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CLSTN1	7105
YWHAZ	6753
VPS35	6719
DLGAP4	5771
CNTNAP1	5764
DISC1	4967
ROCK1	2157
AGO2	712
NEFL	-1526
SEMA7A	-3577
SNX27	-5076

---

GO:0045943 positive regulation of transcription by RNA polymerase I

set	GO:0045943 positive regulation of transcription by RNA polymerase I
setSize	11
pANOVA	0.0268
s.dist	-0.386
p.adjustANOVA	0.264

Top enriched genes

Top 20 genes

GeneID	Gene Rank
WDR75	-6715
HEATR1	-6531
UBTF	-6372
WDR43	-6223
UTP15	-6213
LYAR	-5223
DHX33	-4916
BNC1	-3236
ATF4	1208
ERBB2	5492
EIF2AK3	6892

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
WDR75	-6715
HEATR1	-6531
UBTF	-6372
WDR43	-6223
UTP15	-6213
LYAR	-5223
DHX33	-4916
BNC1	-3236
ATF4	1208
ERBB2	5492
EIF2AK3	6892

---

GO:0032585 multivesicular body membrane

set	GO:0032585 multivesicular body membrane
setSize	12
pANOVA	0.0212
s.dist	0.384
p.adjustANOVA	0.236

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CHMP4C	7068
SLC9A8	6592
CHMP2B	6007
SORL1	5635
CHMP1B	4219
CD63	4088
CHMP5	3668
CHMP7	2284
CHMP3	1721
TMEM9	-902
RAB27A	-1091
CHMP2A	-7090

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CHMP4C	7068
SLC9A8	6592
CHMP2B	6007
SORL1	5635
CHMP1B	4219
CD63	4088
CHMP5	3668
CHMP7	2284
CHMP3	1721
TMEM9	-902
RAB27A	-1091
CHMP2A	-7090

---

GO:0032391 photoreceptor connecting cilium

set	GO:0032391 photoreceptor connecting cilium
setSize	18
pANOVA	0.00479
s.dist	0.384
p.adjustANOVA	0.132

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IFT140	6853
KIFAP3	6617
SEPTIN2	6541
RPGRIP1L	6508
TMEM237	6356
IFT52	5930
WDR19	5785
TTC8	5781
TBCC	3589
GNAT1	3157
IFT20	3135
FAM161A	1118
IQCB1	900
IFT57	-349
USH2A	-524
LCA5	-2027
KIAA1549	-5418
TOPORS	-5708

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IFT140	6853
KIFAP3	6617
SEPTIN2	6541
RPGRIP1L	6508
TMEM237	6356
IFT52	5930
WDR19	5785
TTC8	5781
TBCC	3589
GNAT1	3157
IFT20	3135
FAM161A	1118
IQCB1	900
IFT57	-349
USH2A	-524
LCA5	-2027
KIAA1549	-5418
TOPORS	-5708

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.4.2 (2024-10-31)
## Platform: x86_64-pc-linux-gnu
## Running under: Ubuntu 24.04.1 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.12.0 
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.12.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Australia/Melbourne
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] stats4    stats     graphics  grDevices utils     datasets  methods  
## [8] base     
## 
## other attached packages:
##  [1] pkgload_1.4.0               GGally_2.2.1               
##  [3] ggplot2_3.5.1               gtools_3.9.5               
##  [5] tibble_3.2.1                echarts4r_0.4.5            
##  [7] UpSetR_1.4.0                beeswarm_0.4.0             
##  [9] kableExtra_1.4.0            eulerr_7.0.2               
## [11] mitch_1.19.2                MASS_7.3-61                
## [13] gplots_3.2.0                DESeq2_1.44.0              
## [15] SummarizedExperiment_1.34.0 Biobase_2.64.0             
## [17] MatrixGenerics_1.16.0       matrixStats_1.4.1          
## [19] GenomicRanges_1.56.1        GenomeInfoDb_1.40.1        
## [21] IRanges_2.38.1              S4Vectors_0.42.1           
## [23] BiocGenerics_0.50.0         reshape2_1.4.4             
## [25] dplyr_1.1.4                 zoo_1.8-12                 
## 
## loaded via a namespace (and not attached):
##  [1] tidyselect_1.2.1        viridisLite_0.4.2       farver_2.1.2           
##  [4] bitops_1.0-9            fastmap_1.2.0           promises_1.3.2         
##  [7] digest_0.6.37           mime_0.12               lifecycle_1.0.4        
## [10] polylabelr_0.3.0        magrittr_2.0.3          compiler_4.4.2         
## [13] rlang_1.1.4             sass_0.4.9              tools_4.4.2            
## [16] yaml_2.3.10             knitr_1.49              labeling_0.4.3         
## [19] S4Arrays_1.4.1          htmlwidgets_1.6.4       DelayedArray_0.30.1    
## [22] xml2_1.3.6              plyr_1.8.9              RColorBrewer_1.1-3     
## [25] abind_1.4-8             BiocParallel_1.38.0     KernSmooth_2.23-24     
## [28] withr_3.0.2             purrr_1.0.2             polyclip_1.10-7        
## [31] grid_4.4.2              caTools_1.18.3          xtable_1.8-4           
## [34] colorspace_2.1-1        scales_1.3.0            cli_3.6.3              
## [37] rmarkdown_2.29          crayon_1.5.3            generics_0.1.3         
## [40] rstudioapi_0.17.1       httr_1.4.7              cachem_1.1.0           
## [43] stringr_1.5.1           zlibbioc_1.50.0         parallel_4.4.2         
## [46] XVector_0.44.0          vctrs_0.6.5             Matrix_1.7-1           
## [49] jsonlite_1.8.9          systemfonts_1.1.0       locfit_1.5-9.10        
## [52] jquerylib_0.1.4         tidyr_1.3.1             glue_1.8.0             
## [55] ggstats_0.7.0           codetools_0.2-20        stringi_1.8.4          
## [58] gtable_0.3.6            later_1.4.1             UCSC.utils_1.0.0       
## [61] munsell_0.5.1           pillar_1.10.0           htmltools_0.5.8.1      
## [64] GenomeInfoDbData_1.2.12 R6_2.5.1                evaluate_1.0.1         
## [67] shiny_1.10.0            lattice_0.22-6          httpuv_1.6.15          
## [70] bslib_0.8.0             Rcpp_1.0.13-1           svglite_2.1.3          
## [73] gridExtra_2.3           SparseArray_1.4.8       xfun_0.49              
## [76] pkgconfig_2.0.3

END of report