Mitch Report

date generated: 2025-01-14

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch

	stat
5_8S_rRNA	0.9062060
A4GALT	0.0432395
AAAS	0.3179585
AACS	1.2322414
AADAC	-1.0506931
AADAT	-0.7550449

Here are some metrics about the input data profile:

Profiling data metrics

	Profile metrics
num_genesets	5133
num_genes_in_profile	14402
duplicated_genes_present	0
num_profile_genes_in_sets	9190
num_profile_genes_not_in_sets	5212

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets:

Gene set metrics

	Gene sets metrics
num_genesets	5133
num_genesets_excluded	3365
num_genesets_included	1768

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

set	setSize	pANOVA	s.dist	p.adjustANOVA
GO:0022625 cytosolic large ribosomal subunit	40	9.25e-18	0.784	8.18e-15
GO:0035145 exon-exon junction complex	10	5.17e-05	-0.739	6.09e-03
GO:0002181 cytoplasmic translation	27	3.22e-11	0.738	1.42e-08
GO:0022627 cytosolic small ribosomal subunit	25	4.25e-10	0.721	1.50e-07
GO:1905564 positive regulation of vascular endothelial cell proliferation	10	4.73e-04	0.638	2.99e-02
GO:0036121 double-stranded DNA helicase activity	11	3.01e-04	-0.629	2.32e-02
GO:0004683 calcium/calmodulin-dependent protein kinase activity	11	6.66e-04	0.593	3.46e-02
GO:0004602 glutathione peroxidase activity	12	6.05e-04	0.572	3.28e-02
GO:1990391 DNA repair complex	10	3.55e-03	-0.532	9.10e-02
GO:0140662 ATP-dependent protein folding chaperone	23	1.17e-05	-0.528	2.07e-03
GO:0006623 protein targeting to vacuole	11	2.78e-03	-0.521	7.94e-02
GO:0035925 mRNA 3’-UTR AU-rich region binding	13	1.41e-03	0.511	5.34e-02
GO:0003735 structural constituent of ribosome	118	1.19e-21	0.509	2.10e-18
GO:2000648 positive regulation of stem cell proliferation	12	2.45e-03	0.505	7.37e-02
GO:0030127 COPII vesicle coat	10	5.88e-03	0.503	1.18e-01
GO:0009378 four-way junction helicase activity	13	1.81e-03	-0.500	5.83e-02
GO:0003724 RNA helicase activity	37	2.26e-07	-0.492	5.83e-05
GO:0008593 regulation of Notch signaling pathway	10	7.23e-03	0.491	1.29e-01
GO:1990518 single-stranded 3’-5’ DNA helicase activity	11	5.38e-03	-0.485	1.14e-01
GO:0140861 DNA repair-dependent chromatin remodeling	14	1.73e-03	-0.484	5.69e-02
GO:0003678 DNA helicase activity	20	1.96e-04	-0.481	1.82e-02
GO:0097038 perinuclear endoplasmic reticulum	10	8.92e-03	0.478	1.43e-01
GO:0005544 calcium-dependent phospholipid binding	21	1.69e-04	0.474	1.66e-02
GO:0007042 lysosomal lumen acidification	10	9.47e-03	0.474	1.47e-01
GO:0042474 middle ear morphogenesis	10	9.50e-03	0.474	1.47e-01
GO:0061749 forked DNA-dependent helicase activity	10	9.86e-03	-0.471	1.48e-01
GO:0060216 definitive hemopoiesis	10	1.16e-02	0.461	1.63e-01
GO:0001819 positive regulation of cytokine production	13	4.38e-03	0.456	1.01e-01
GO:0070034 telomerase RNA binding	12	6.27e-03	-0.456	1.22e-01
GO:0090110 COPII-coated vesicle cargo loading	10	1.45e-02	0.447	1.83e-01
GO:0070182 DNA polymerase binding	13	5.41e-03	-0.446	1.14e-01
GO:0012506 vesicle membrane	15	3.40e-03	0.437	9.10e-02
GO:0000245 spliceosomal complex assembly	10	1.69e-02	-0.436	1.92e-01
GO:0030020 extracellular matrix structural constituent conferring tensile strength	17	1.93e-03	0.434	6.09e-02
GO:0030992 intraciliary transport particle B	15	3.66e-03	0.433	9.10e-02
GO:0009888 tissue development	18	1.57e-03	-0.430	5.44e-02
GO:0007099 centriole replication	13	7.89e-03	0.426	1.37e-01
GO:0006412 translation	96	6.35e-13	0.425	3.74e-10
GO:0004364 glutathione transferase activity	10	2.04e-02	0.423	2.21e-01
GO:0141198 protein branched polyubiquitination	13	8.57e-03	-0.421	1.40e-01
GO:0005791 rough endoplasmic reticulum	12	1.19e-02	-0.419	1.63e-01
GO:0000774 adenyl-nucleotide exchange factor activity	12	1.20e-02	-0.419	1.63e-01
GO:0051642 centrosome localization	14	6.70e-03	0.419	1.29e-01
GO:0070507 regulation of microtubule cytoskeleton organization	14	6.98e-03	0.416	1.29e-01
GO:0045292 mRNA cis splicing, via spliceosome	13	9.67e-03	-0.415	1.47e-01
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle	14	7.50e-03	-0.413	1.33e-01
GO:0032924 activin receptor signaling pathway	12	1.43e-02	-0.408	1.82e-01
GO:0061775 cohesin loader activity	24	5.36e-04	-0.408	3.16e-02
GO:0140588 chromatin looping	27	2.55e-04	-0.407	2.06e-02
GO:0048041 focal adhesion assembly	14	8.50e-03	-0.406	1.40e-01

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
GO:0022625 cytosolic large ribosomal subunit	40	9.25e-18	7.84e-01	8.18e-15
GO:0035145 exon-exon junction complex	10	5.17e-05	-7.39e-01	6.09e-03
GO:0002181 cytoplasmic translation	27	3.22e-11	7.38e-01	1.42e-08
GO:0022627 cytosolic small ribosomal subunit	25	4.25e-10	7.21e-01	1.50e-07
GO:1905564 positive regulation of vascular endothelial cell proliferation	10	4.73e-04	6.38e-01	2.99e-02
GO:0036121 double-stranded DNA helicase activity	11	3.01e-04	-6.29e-01	2.32e-02
GO:0004683 calcium/calmodulin-dependent protein kinase activity	11	6.66e-04	5.93e-01	3.46e-02
GO:0004602 glutathione peroxidase activity	12	6.05e-04	5.72e-01	3.28e-02
GO:1990391 DNA repair complex	10	3.55e-03	-5.32e-01	9.10e-02
GO:0140662 ATP-dependent protein folding chaperone	23	1.17e-05	-5.28e-01	2.07e-03
GO:0006623 protein targeting to vacuole	11	2.78e-03	-5.21e-01	7.94e-02
GO:0035925 mRNA 3’-UTR AU-rich region binding	13	1.41e-03	5.11e-01	5.34e-02
GO:0003735 structural constituent of ribosome	118	1.19e-21	5.09e-01	2.10e-18
GO:2000648 positive regulation of stem cell proliferation	12	2.45e-03	5.05e-01	7.37e-02
GO:0030127 COPII vesicle coat	10	5.88e-03	5.03e-01	1.18e-01
GO:0009378 four-way junction helicase activity	13	1.81e-03	-5.00e-01	5.83e-02
GO:0003724 RNA helicase activity	37	2.26e-07	-4.92e-01	5.83e-05
GO:0008593 regulation of Notch signaling pathway	10	7.23e-03	4.91e-01	1.29e-01
GO:1990518 single-stranded 3’-5’ DNA helicase activity	11	5.38e-03	-4.85e-01	1.14e-01
GO:0140861 DNA repair-dependent chromatin remodeling	14	1.73e-03	-4.84e-01	5.69e-02
GO:0003678 DNA helicase activity	20	1.96e-04	-4.81e-01	1.82e-02
GO:0097038 perinuclear endoplasmic reticulum	10	8.92e-03	4.78e-01	1.43e-01
GO:0005544 calcium-dependent phospholipid binding	21	1.69e-04	4.74e-01	1.66e-02
GO:0007042 lysosomal lumen acidification	10	9.47e-03	4.74e-01	1.47e-01
GO:0042474 middle ear morphogenesis	10	9.50e-03	4.74e-01	1.47e-01
GO:0061749 forked DNA-dependent helicase activity	10	9.86e-03	-4.71e-01	1.48e-01
GO:0060216 definitive hemopoiesis	10	1.16e-02	4.61e-01	1.63e-01
GO:0001819 positive regulation of cytokine production	13	4.38e-03	4.56e-01	1.01e-01
GO:0070034 telomerase RNA binding	12	6.27e-03	-4.56e-01	1.22e-01
GO:0090110 COPII-coated vesicle cargo loading	10	1.45e-02	4.47e-01	1.83e-01
GO:0070182 DNA polymerase binding	13	5.41e-03	-4.46e-01	1.14e-01
GO:0012506 vesicle membrane	15	3.40e-03	4.37e-01	9.10e-02
GO:0000245 spliceosomal complex assembly	10	1.69e-02	-4.36e-01	1.92e-01
GO:0030020 extracellular matrix structural constituent conferring tensile strength	17	1.93e-03	4.34e-01	6.09e-02
GO:0030992 intraciliary transport particle B	15	3.66e-03	4.33e-01	9.10e-02
GO:0009888 tissue development	18	1.57e-03	-4.30e-01	5.44e-02
GO:0007099 centriole replication	13	7.89e-03	4.26e-01	1.37e-01
GO:0006412 translation	96	6.35e-13	4.25e-01	3.74e-10
GO:0004364 glutathione transferase activity	10	2.04e-02	4.23e-01	2.21e-01
GO:0141198 protein branched polyubiquitination	13	8.57e-03	-4.21e-01	1.40e-01
GO:0005791 rough endoplasmic reticulum	12	1.19e-02	-4.19e-01	1.63e-01
GO:0000774 adenyl-nucleotide exchange factor activity	12	1.20e-02	-4.19e-01	1.63e-01
GO:0051642 centrosome localization	14	6.70e-03	4.19e-01	1.29e-01
GO:0070507 regulation of microtubule cytoskeleton organization	14	6.98e-03	4.16e-01	1.29e-01
GO:0045292 mRNA cis splicing, via spliceosome	13	9.67e-03	-4.15e-01	1.47e-01
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle	14	7.50e-03	-4.13e-01	1.33e-01
GO:0032924 activin receptor signaling pathway	12	1.43e-02	-4.08e-01	1.82e-01
GO:0061775 cohesin loader activity	24	5.36e-04	-4.08e-01	3.16e-02
GO:0140588 chromatin looping	27	2.55e-04	-4.07e-01	2.06e-02
GO:0048041 focal adhesion assembly	14	8.50e-03	-4.06e-01	1.40e-01
GO:0140584 chromatin extrusion motor activity	23	7.56e-04	-4.06e-01	3.52e-02
GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity	23	7.56e-04	-4.06e-01	3.52e-02
GO:0140849 ATP-dependent H2AZ histone chaperone activity	23	7.56e-04	-4.06e-01	3.52e-02
GO:0017056 structural constituent of nuclear pore	19	2.28e-03	-4.04e-01	7.08e-02
GO:0043995 histone H4K5 acetyltransferase activity	10	2.71e-02	-4.04e-01	2.42e-01
GO:0043996 histone H4K8 acetyltransferase activity	10	2.71e-02	-4.04e-01	2.42e-01
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway	11	2.16e-02	4.00e-01	2.26e-01
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage	24	7.17e-04	-3.99e-01	3.52e-02
GO:0002218 activation of innate immune response	17	4.60e-03	-3.97e-01	1.02e-01
GO:0006749 glutathione metabolic process	15	8.08e-03	3.95e-01	1.39e-01
GO:0070577 lysine-acetylated histone binding	16	6.25e-03	-3.95e-01	1.22e-01
GO:0005852 eukaryotic translation initiation factor 3 complex	10	3.20e-02	3.92e-01	2.63e-01
GO:1903076 regulation of protein localization to plasma membrane	18	4.04e-03	3.91e-01	9.40e-02
GO:0038202 TORC1 signaling	12	1.92e-02	3.90e-01	2.12e-01
GO:0034727 piecemeal microautophagy of the nucleus	13	1.50e-02	3.90e-01	1.87e-01
GO:0030665 clathrin-coated vesicle membrane	11	2.53e-02	3.90e-01	2.34e-01
GO:2000352 negative regulation of endothelial cell apoptotic process	14	1.17e-02	3.89e-01	1.63e-01
GO:0031982 vesicle	26	6.13e-04	3.88e-01	3.28e-02
GO:0005840 ribosome	43	1.10e-05	3.88e-01	2.07e-03
GO:0016442 RISC complex	11	2.61e-02	-3.87e-01	2.38e-01
GO:0006120 mitochondrial electron transport, NADH to ubiquinone	19	3.94e-03	3.82e-01	9.40e-02
GO:0098869 cellular oxidant detoxification	28	4.99e-04	3.80e-01	3.04e-02
GO:0001675 acrosome assembly	11	2.91e-02	3.80e-01	2.50e-01
GO:0032585 multivesicular body membrane	12	2.31e-02	3.79e-01	2.30e-01
GO:0001725 stress fiber	42	2.40e-05	-3.77e-01	3.54e-03
GO:0045116 protein neddylation	10	3.92e-02	3.77e-01	2.85e-01
GO:0042026 protein refolding	12	2.41e-02	-3.76e-01	2.33e-01
GO:0000380 alternative mRNA splicing, via spliceosome	16	9.59e-03	-3.74e-01	1.47e-01
GO:0090128 regulation of synapse maturation	10	4.07e-02	3.74e-01	2.92e-01
GO:1904646 cellular response to amyloid-beta	11	3.20e-02	3.73e-01	2.63e-01
GO:0060170 ciliary membrane	20	3.87e-03	3.73e-01	9.40e-02
GO:0051453 regulation of intracellular pH	14	1.61e-02	3.72e-01	1.92e-01
GO:0060395 SMAD protein signal transduction	14	1.66e-02	-3.70e-01	1.92e-01
GO:0045943 positive regulation of transcription by RNA polymerase I	11	3.39e-02	-3.69e-01	2.71e-01
GO:0046961 proton-transporting ATPase activity, rotational mechanism	14	1.68e-02	3.69e-01	1.92e-01
GO:0060349 bone morphogenesis	12	2.79e-02	3.67e-01	2.47e-01
GO:0000423 mitophagy	31	4.18e-04	3.66e-01	2.96e-02
GO:0042056 chemoattractant activity	11	3.60e-02	3.65e-01	2.74e-01
GO:0055074 calcium ion homeostasis	18	7.62e-03	3.63e-01	1.33e-01
GO:0035269 protein O-linked mannosylation	13	2.36e-02	-3.63e-01	2.33e-01
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	13	2.44e-02	-3.61e-01	2.33e-01
GO:0044295 axonal growth cone	11	3.84e-02	-3.61e-01	2.83e-01
GO:0042073 intraciliary transport	16	1.29e-02	3.59e-01	1.70e-01
GO:0030904 retromer complex	15	1.72e-02	3.55e-01	1.93e-01
GO:0008137 NADH dehydrogenase (ubiquinone) activity	10	5.18e-02	3.55e-01	3.19e-01
GO:0061952 midbody abscission	14	2.15e-02	3.55e-01	2.26e-01
GO:0044458 motile cilium assembly	12	3.51e-02	3.51e-01	2.72e-01
GO:2000377 regulation of reactive oxygen species metabolic process	10	5.47e-02	3.51e-01	3.26e-01
GO:1904294 positive regulation of ERAD pathway	10	5.61e-02	3.49e-01	3.28e-01
GO:0007017 microtubule-based process	11	4.64e-02	3.47e-01	3.08e-01
GO:0006406 mRNA export from nucleus	28	1.53e-03	-3.46e-01	5.42e-02
GO:0030031 cell projection assembly	10	5.84e-02	3.46e-01	3.35e-01
GO:0005680 anaphase-promoting complex	13	3.15e-02	-3.45e-01	2.63e-01
GO:0071897 DNA biosynthetic process	12	3.90e-02	-3.44e-01	2.85e-01
GO:0050829 defense response to Gram-negative bacterium	12	3.94e-02	3.43e-01	2.86e-01
GO:0016829 lyase activity	15	2.30e-02	3.39e-01	2.30e-01
GO:1903077 negative regulation of protein localization to plasma membrane	14	2.81e-02	3.39e-01	2.47e-01
GO:0022604 regulation of cell morphogenesis	14	2.90e-02	-3.37e-01	2.50e-01
GO:0071108 protein K48-linked deubiquitination	15	2.39e-02	-3.37e-01	2.33e-01
GO:0005902 microvillus	29	1.74e-03	3.36e-01	5.69e-02
GO:0051393 alpha-actinin binding	10	6.66e-02	-3.35e-01	3.47e-01
GO:0045271 respiratory chain complex I	31	1.26e-03	3.35e-01	5.05e-02
GO:0051603 proteolysis involved in protein catabolic process	23	5.64e-03	3.33e-01	1.17e-01
GO:0008139 nuclear localization sequence binding	13	3.77e-02	-3.33e-01	2.79e-01
GO:0030100 regulation of endocytosis	12	4.61e-02	3.32e-01	3.08e-01
GO:0031145 anaphase-promoting complex-dependent catabolic process	14	3.23e-02	-3.31e-01	2.63e-01
GO:0016236 macroautophagy	16	2.24e-02	3.30e-01	2.29e-01
GO:0000407 phagophore assembly site	20	1.08e-02	3.29e-01	1.57e-01
GO:0030016 myofibril	13	4.11e-02	-3.27e-01	2.94e-01
GO:0045332 phospholipid translocation	15	2.85e-02	3.27e-01	2.49e-01
GO:0080025 phosphatidylinositol-3,5-bisphosphate binding	15	3.02e-02	3.23e-01	2.56e-01
GO:0015030 Cajal body	26	4.44e-03	-3.22e-01	1.01e-01
GO:0050918 positive chemotaxis	13	4.50e-02	3.21e-01	3.07e-01
GO:0030225 macrophage differentiation	11	6.54e-02	3.21e-01	3.44e-01
GO:0005774 vacuolar membrane	10	7.98e-02	3.20e-01	3.82e-01
GO:0071353 cellular response to interleukin-4	10	7.99e-02	3.20e-01	3.82e-01
GO:0035615 clathrin adaptor activity	10	8.01e-02	3.20e-01	3.82e-01
GO:0015914 phospholipid transport	25	5.69e-03	3.20e-01	1.17e-01
GO:0070411 I-SMAD binding	11	6.74e-02	-3.19e-01	3.47e-01
GO:0006744 ubiquinone biosynthetic process	11	6.78e-02	3.18e-01	3.47e-01
GO:0034314 Arp2/3 complex-mediated actin nucleation	11	6.82e-02	3.18e-01	3.47e-01
GO:0006936 muscle contraction	10	8.21e-02	-3.18e-01	3.86e-01
GO:0070971 endoplasmic reticulum exit site	19	1.70e-02	3.16e-01	1.92e-01
GO:0007339 binding of sperm to zona pellucida	11	6.94e-02	-3.16e-01	3.52e-01
GO:0031669 cellular response to nutrient levels	13	4.84e-02	-3.16e-01	3.11e-01
GO:0006337 nucleosome disassembly	10	8.39e-02	-3.16e-01	3.88e-01
GO:0034045 phagophore assembly site membrane	12	5.96e-02	3.14e-01	3.35e-01
GO:0043997 histone H4K12 acetyltransferase activity	10	8.56e-02	-3.14e-01	3.88e-01
GO:1904019 epithelial cell apoptotic process	13	5.00e-02	3.14e-01	3.16e-01
GO:0016514 SWI/SNF complex	20	1.52e-02	-3.13e-01	1.87e-01
GO:0048306 calcium-dependent protein binding	20	1.53e-02	3.13e-01	1.87e-01
GO:0097225 sperm midpiece	14	4.24e-02	3.13e-01	3.00e-01
GO:0006913 nucleocytoplasmic transport	18	2.18e-02	-3.12e-01	2.27e-01
GO:0140658 ATP-dependent chromatin remodeler activity	11	7.49e-02	-3.10e-01	3.69e-01
GO:0060379 cardiac muscle cell myoblast differentiation	10	8.96e-02	-3.10e-01	3.99e-01
GO:0043024 ribosomal small subunit binding	13	5.47e-02	-3.08e-01	3.26e-01
GO:0002230 positive regulation of defense response to virus by host	11	7.76e-02	-3.07e-01	3.78e-01
GO:0071577 zinc ion transmembrane transport	10	9.30e-02	-3.07e-01	4.07e-01
GO:0033290 eukaryotic 48S preinitiation complex	13	5.78e-02	3.04e-01	3.34e-01
GO:0048018 receptor ligand activity	18	2.63e-02	-3.03e-01	2.38e-01
GO:0030687 preribosome, large subunit precursor	12	7.04e-02	-3.02e-01	3.55e-01
GO:0005044 scavenger receptor activity	10	9.88e-02	3.01e-01	4.19e-01
GO:0045739 positive regulation of DNA repair	20	1.97e-02	-3.01e-01	2.15e-01
GO:0032968 positive regulation of transcription elongation by RNA polymerase II	15	4.38e-02	-3.01e-01	3.05e-01
GO:0005665 RNA polymerase II, core complex	10	1.00e-01	3.00e-01	4.20e-01
GO:0000422 autophagy of mitochondrion	14	5.23e-02	3.00e-01	3.19e-01
GO:0005049 nuclear export signal receptor activity	10	1.02e-01	-2.99e-01	4.22e-01
GO:0030030 cell projection organization	13	6.28e-02	2.98e-01	3.44e-01
GO:0010977 negative regulation of neuron projection development	18	2.94e-02	-2.97e-01	2.51e-01
GO:0017018 myosin phosphatase activity	13	6.49e-02	-2.96e-01	3.44e-01
GO:0140791 histone H2AXS140 phosphatase activity	13	6.49e-02	-2.96e-01	3.44e-01
GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	13	6.49e-02	-2.96e-01	3.44e-01
GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	13	6.49e-02	-2.96e-01	3.44e-01
GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	13	6.49e-02	-2.96e-01	3.44e-01
GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	13	6.49e-02	-2.96e-01	3.44e-01
GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	13	6.49e-02	-2.96e-01	3.44e-01
GO:1990439 MAP kinase serine/threonine phosphatase activity	13	6.49e-02	-2.96e-01	3.44e-01
GO:0004888 transmembrane signaling receptor activity	23	1.43e-02	2.95e-01	1.82e-01
GO:0060047 heart contraction	10	1.06e-01	2.95e-01	4.30e-01
GO:0021987 cerebral cortex development	25	1.10e-02	2.94e-01	1.58e-01
GO:0022626 cytosolic ribosome	13	6.67e-02	-2.94e-01	3.47e-01
GO:0051010 microtubule plus-end binding	11	9.23e-02	2.93e-01	4.07e-01
GO:0080008 Cul4-RING E3 ubiquitin ligase complex	13	6.73e-02	-2.93e-01	3.47e-01
GO:0071560 cellular response to transforming growth factor beta stimulus	16	4.46e-02	2.90e-01	3.06e-01
GO:0001772 immunological synapse	23	1.62e-02	2.90e-01	1.92e-01
GO:0045070 positive regulation of viral genome replication	19	2.88e-02	-2.90e-01	2.50e-01
GO:0048704 embryonic skeletal system morphogenesis	18	3.35e-02	2.90e-01	2.69e-01
GO:0032212 positive regulation of telomere maintenance via telomerase	17	3.97e-02	-2.88e-01	2.87e-01
GO:0001732 formation of cytoplasmic translation initiation complex	12	8.40e-02	2.88e-01	3.88e-01
GO:0031462 Cul2-RING ubiquitin ligase complex	15	5.35e-02	-2.88e-01	3.24e-01
GO:0048872 homeostasis of number of cells	14	6.27e-02	2.87e-01	3.44e-01
GO:0000792 heterochromatin	19	3.12e-02	-2.85e-01	2.63e-01
GO:0043029 T cell homeostasis	13	7.49e-02	-2.85e-01	3.69e-01
GO:0045216 cell-cell junction organization	13	7.59e-02	-2.84e-01	3.72e-01
GO:0035267 NuA4 histone acetyltransferase complex	18	3.68e-02	-2.84e-01	2.76e-01
GO:0020037 heme binding	51	4.55e-04	2.84e-01	2.99e-02
GO:0071782 endoplasmic reticulum tubular network	12	8.94e-02	-2.83e-01	3.99e-01
GO:0032508 DNA duplex unwinding	44	1.18e-03	-2.83e-01	5.05e-02
GO:0051721 protein phosphatase 2A binding	14	6.71e-02	-2.83e-01	3.47e-01
GO:0043616 keratinocyte proliferation	11	1.05e-01	2.82e-01	4.30e-01
GO:1902774 late endosome to lysosome transport	10	1.22e-01	2.82e-01	4.58e-01
GO:0048701 embryonic cranial skeleton morphogenesis	13	7.83e-02	2.82e-01	3.78e-01
GO:0030863 cortical cytoskeleton	10	1.23e-01	2.82e-01	4.58e-01
GO:0030316 osteoclast differentiation	29	8.65e-03	-2.82e-01	1.40e-01
GO:0044322 endoplasmic reticulum quality control compartment	11	1.06e-01	2.82e-01	4.30e-01
GO:0030199 collagen fibril organization	31	7.14e-03	2.79e-01	1.29e-01
GO:0030515 snoRNA binding	14	7.09e-02	-2.79e-01	3.56e-01
GO:0046716 muscle cell cellular homeostasis	15	6.16e-02	-2.79e-01	3.42e-01
GO:0035278 miRNA-mediated gene silencing by inhibition of translation	12	9.60e-02	-2.78e-01	4.14e-01
GO:0005901 caveola	28	1.15e-02	2.76e-01	1.63e-01
GO:0050840 extracellular matrix binding	17	4.92e-02	2.76e-01	3.15e-01
GO:0005249 voltage-gated potassium channel activity	15	6.51e-02	-2.75e-01	3.44e-01
GO:1903543 positive regulation of exosomal secretion	10	1.33e-01	2.75e-01	4.75e-01
GO:0005905 clathrin-coated pit	30	9.61e-03	2.73e-01	1.47e-01
GO:0035914 skeletal muscle cell differentiation	24	2.09e-02	-2.72e-01	2.24e-01
GO:0002682 regulation of immune system process	11	1.20e-01	-2.71e-01	4.55e-01
GO:0071549 cellular response to dexamethasone stimulus	11	1.22e-01	2.69e-01	4.56e-01
GO:0031624 ubiquitin conjugating enzyme binding	17	5.49e-02	-2.69e-01	3.26e-01
GO:0048813 dendrite morphogenesis	21	3.31e-02	2.69e-01	2.67e-01
GO:0002224 toll-like receptor signaling pathway	14	8.20e-02	2.69e-01	3.86e-01
GO:0035770 ribonucleoprotein granule	13	9.38e-02	-2.68e-01	4.09e-01
GO:0035994 response to muscle stretch	10	1.43e-01	-2.67e-01	4.94e-01
GO:0044331 cell-cell adhesion mediated by cadherin	11	1.26e-01	2.67e-01	4.64e-01
GO:0000281 mitotic cytokinesis	34	7.21e-03	2.66e-01	1.29e-01
GO:0031623 receptor internalization	21	3.49e-02	2.66e-01	2.72e-01
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT	11	1.28e-01	2.65e-01	4.67e-01
GO:0000307 cyclin-dependent protein kinase holoenzyme complex	21	3.58e-02	2.65e-01	2.74e-01
GO:2001235 positive regulation of apoptotic signaling pathway	17	5.95e-02	2.64e-01	3.35e-01
GO:0008266 poly(U) RNA binding	16	6.81e-02	2.63e-01	3.47e-01
GO:0000421 autophagosome membrane	23	2.88e-02	2.63e-01	2.50e-01
GO:0030900 forebrain development	20	4.19e-02	-2.63e-01	2.98e-01
GO:0001958 endochondral ossification	15	7.82e-02	2.63e-01	3.78e-01
GO:2000773 negative regulation of cellular senescence	12	1.16e-01	2.62e-01	4.49e-01
GO:0030866 cortical actin cytoskeleton organization	20	4.30e-02	2.61e-01	3.02e-01
GO:0035869 ciliary transition zone	22	3.44e-02	2.61e-01	2.72e-01
GO:0010508 positive regulation of autophagy	39	5.03e-03	2.60e-01	1.08e-01
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway	11	1.36e-01	2.59e-01	4.82e-01
GO:0097718 disordered domain specific binding	15	8.22e-02	-2.59e-01	3.86e-01
GO:0019003 GDP binding	44	2.98e-03	2.59e-01	8.36e-02
GO:0006096 glycolytic process	23	3.19e-02	2.58e-01	2.63e-01
GO:0071711 basement membrane organization	11	1.39e-01	2.58e-01	4.84e-01
GO:0007259 cell surface receptor signaling pathway via JAK-STAT	21	4.13e-02	2.57e-01	2.95e-01
GO:0030897 HOPS complex	10	1.59e-01	-2.57e-01	5.20e-01
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	17	6.68e-02	-2.57e-01	3.47e-01
GO:0032391 photoreceptor connecting cilium	18	5.97e-02	2.56e-01	3.35e-01
GO:0007163 establishment or maintenance of cell polarity	13	1.10e-01	2.56e-01	4.36e-01
GO:0010839 negative regulation of keratinocyte proliferation	14	1.01e-01	2.53e-01	4.21e-01
GO:0006334 nucleosome assembly	27	2.32e-02	-2.53e-01	2.30e-01
GO:0040029 epigenetic regulation of gene expression	18	6.37e-02	-2.52e-01	3.44e-01
GO:0031929 TOR signaling	13	1.16e-01	2.52e-01	4.49e-01
GO:0000793 condensed chromosome	13	1.17e-01	-2.51e-01	4.50e-01
GO:0043409 negative regulation of MAPK cascade	20	5.18e-02	-2.51e-01	3.19e-01
GO:0031514 motile cilium	37	8.24e-03	2.51e-01	1.40e-01
GO:2000300 regulation of synaptic vesicle exocytosis	19	5.87e-02	2.51e-01	3.35e-01
GO:0043240 Fanconi anaemia nuclear complex	11	1.51e-01	2.50e-01	5.03e-01
GO:0045177 apical part of cell	35	1.07e-02	2.49e-01	1.56e-01
GO:0000786 nucleosome	16	8.45e-02	-2.49e-01	3.88e-01
GO:0001786 phosphatidylserine binding	24	3.49e-02	2.49e-01	2.72e-01
GO:0043531 ADP binding	21	4.84e-02	-2.49e-01	3.11e-01
GO:0044344 cellular response to fibroblast growth factor stimulus	10	1.76e-01	2.47e-01	5.40e-01
GO:0099149 regulation of postsynaptic neurotransmitter receptor internalization	12	1.38e-01	2.47e-01	4.84e-01
GO:0032008 positive regulation of TOR signaling	12	1.41e-01	2.46e-01	4.88e-01
GO:0016757 glycosyltransferase activity	15	9.95e-02	-2.46e-01	4.20e-01
GO:0030136 clathrin-coated vesicle	29	2.21e-02	2.46e-01	2.28e-01
GO:0001965 G-protein alpha-subunit binding	10	1.79e-01	2.46e-01	5.47e-01
GO:0002040 sprouting angiogenesis	18	7.16e-02	-2.45e-01	3.59e-01
GO:0032720 negative regulation of tumor necrosis factor production	18	7.21e-02	-2.45e-01	3.59e-01
GO:0003727 single-stranded RNA binding	21	5.24e-02	-2.45e-01	3.19e-01
GO:0034704 calcium channel complex	11	1.60e-01	2.44e-01	5.20e-01
GO:0061512 protein localization to cilium	22	4.73e-02	2.44e-01	3.10e-01
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	13	1.27e-01	2.44e-01	4.67e-01
GO:0001750 photoreceptor outer segment	22	4.77e-02	2.44e-01	3.10e-01
GO:0015908 fatty acid transport	11	1.62e-01	2.44e-01	5.20e-01
GO:0032728 positive regulation of interferon-beta production	15	1.03e-01	-2.43e-01	4.29e-01
GO:0060261 positive regulation of transcription initiation by RNA polymerase II	30	2.15e-02	-2.43e-01	2.26e-01
GO:0071363 cellular response to growth factor stimulus	20	6.08e-02	-2.42e-01	3.38e-01
GO:0000723 telomere maintenance	29	2.41e-02	-2.42e-01	2.33e-01
GO:0001530 lipopolysaccharide binding	12	1.46e-01	2.42e-01	4.99e-01
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding	21	5.52e-02	2.42e-01	3.26e-01
GO:0032420 stereocilium	14	1.17e-01	2.42e-01	4.51e-01
GO:0071230 cellular response to amino acid stimulus	29	2.47e-02	2.41e-01	2.33e-01
GO:0016282 eukaryotic 43S preinitiation complex	14	1.19e-01	2.41e-01	4.53e-01
GO:0048027 mRNA 5’-UTR binding	19	6.91e-02	2.41e-01	3.51e-01
GO:0030018 Z disc	49	3.57e-03	-2.41e-01	9.10e-02
GO:0008277 regulation of G protein-coupled receptor signaling pathway	15	1.07e-01	2.41e-01	4.30e-01
GO:0007249 canonical NF-kappaB signal transduction	18	7.79e-02	-2.40e-01	3.78e-01
GO:0140326 ATPase-coupled intramembrane lipid transporter activity	11	1.69e-01	2.40e-01	5.31e-01
GO:0031681 G-protein beta-subunit binding	10	1.89e-01	2.40e-01	5.63e-01
GO:0046034 ATP metabolic process	13	1.35e-01	-2.39e-01	4.80e-01
GO:0007218 neuropeptide signaling pathway	15	1.09e-01	2.39e-01	4.36e-01
GO:0050796 regulation of insulin secretion	12	1.53e-01	2.39e-01	5.05e-01
GO:0071333 cellular response to glucose stimulus	12	1.53e-01	-2.38e-01	5.05e-01
GO:0048488 synaptic vesicle endocytosis	21	5.93e-02	2.38e-01	3.35e-01
GO:0031210 phosphatidylcholine binding	17	9.01e-02	2.38e-01	4.00e-01
GO:0008253 5’-nucleotidase activity	10	1.94e-01	-2.37e-01	5.66e-01
GO:0051233 spindle midzone	17	9.04e-02	2.37e-01	4.00e-01
GO:0015631 tubulin binding	27	3.31e-02	2.37e-01	2.67e-01
GO:0046847 filopodium assembly	11	1.74e-01	2.37e-01	5.36e-01
GO:0071346 cellular response to type II interferon	24	4.46e-02	2.37e-01	3.06e-01
GO:0030133 transport vesicle	23	5.02e-02	2.36e-01	3.16e-01
GO:0060045 positive regulation of cardiac muscle cell proliferation	13	1.41e-01	-2.36e-01	4.89e-01
GO:0000077 DNA damage checkpoint signaling	26	3.87e-02	-2.34e-01	2.84e-01
GO:0034707 chloride channel complex	10	2.00e-01	2.34e-01	5.77e-01
GO:0030658 transport vesicle membrane	13	1.44e-01	2.34e-01	4.96e-01
GO:0001968 fibronectin binding	10	2.01e-01	-2.34e-01	5.77e-01
GO:0007076 mitotic chromosome condensation	10	2.02e-01	2.33e-01	5.77e-01
GO:0006352 DNA-templated transcription initiation	11	1.81e-01	-2.33e-01	5.49e-01
GO:0031663 lipopolysaccharide-mediated signaling pathway	10	2.02e-01	2.33e-01	5.77e-01
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	21	6.51e-02	-2.33e-01	3.44e-01
GO:0070979 protein K11-linked ubiquitination	22	5.94e-02	-2.32e-01	3.35e-01
GO:0001938 positive regulation of endothelial cell proliferation	23	5.45e-02	2.32e-01	3.26e-01
GO:0006094 gluconeogenesis	20	7.32e-02	2.31e-01	3.63e-01
GO:0051491 positive regulation of filopodium assembly	15	1.21e-01	-2.31e-01	4.56e-01
GO:0000149 SNARE binding	31	2.61e-02	2.31e-01	2.38e-01
GO:0061709 reticulophagy	15	1.22e-01	2.31e-01	4.56e-01
GO:0030097 hemopoiesis	25	4.60e-02	2.31e-01	3.08e-01
GO:0032981 mitochondrial respiratory chain complex I assembly	38	1.41e-02	2.30e-01	1.82e-01
GO:0032496 response to lipopolysaccharide	37	1.57e-02	2.30e-01	1.89e-01
GO:0005254 chloride channel activity	19	8.33e-02	2.30e-01	3.88e-01
GO:0034142 toll-like receptor 4 signaling pathway	14	1.38e-01	2.29e-01	4.84e-01
GO:0045444 fat cell differentiation	44	8.58e-03	2.29e-01	1.40e-01
GO:0003689 DNA clamp loader activity	32	2.50e-02	-2.29e-01	2.33e-01
GO:0030513 positive regulation of BMP signaling pathway	20	7.65e-02	-2.29e-01	3.74e-01
GO:0097060 synaptic membrane	11	1.92e-01	-2.27e-01	5.66e-01
GO:0004197 cysteine-type endopeptidase activity	37	1.67e-02	2.27e-01	1.92e-01
GO:0009792 embryo development ending in birth or egg hatching	10	2.14e-01	-2.27e-01	5.91e-01
GO:0043408 regulation of MAPK cascade	21	7.19e-02	-2.27e-01	3.59e-01
GO:0035025 positive regulation of Rho protein signal transduction	10	2.14e-01	-2.27e-01	5.91e-01
GO:0042733 embryonic digit morphogenesis	30	3.19e-02	2.26e-01	2.63e-01
GO:0050885 neuromuscular process controlling balance	24	5.51e-02	-2.26e-01	3.26e-01
GO:0006364 rRNA processing	65	1.63e-03	-2.26e-01	5.54e-02
GO:0005777 peroxisome	49	6.29e-03	2.26e-01	1.22e-01
GO:0030170 pyridoxal phosphate binding	33	2.50e-02	2.25e-01	2.33e-01
GO:1990841 promoter-specific chromatin binding	34	2.30e-02	-2.25e-01	2.30e-01
GO:0009408 response to heat	19	8.91e-02	-2.25e-01	3.99e-01
GO:0046875 ephrin receptor binding	17	1.08e-01	2.25e-01	4.33e-01
GO:0002039 p53 binding	44	9.77e-03	-2.25e-01	1.48e-01
GO:0002088 lens development in camera-type eye	13	1.62e-01	-2.24e-01	5.20e-01
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment	35	2.20e-02	2.24e-01	2.27e-01
GO:0007389 pattern specification process	14	1.47e-01	2.24e-01	4.99e-01
GO:0030017 sarcomere	13	1.63e-01	2.24e-01	5.21e-01
GO:0003713 transcription coactivator activity	128	1.29e-05	-2.24e-01	2.07e-03
GO:0005879 axonemal microtubule	10	2.21e-01	2.23e-01	5.95e-01
GO:0009791 post-embryonic development	36	2.10e-02	-2.22e-01	2.24e-01
GO:0030041 actin filament polymerization	16	1.24e-01	2.22e-01	4.61e-01
GO:0060291 long-term synaptic potentiation	11	2.03e-01	-2.22e-01	5.77e-01
GO:0043687 post-translational protein modification	19	9.47e-02	2.21e-01	4.11e-01
GO:0097730 non-motile cilium	14	1.52e-01	2.21e-01	5.04e-01
GO:0099175 regulation of postsynapse organization	20	8.67e-02	2.21e-01	3.92e-01
GO:0010569 regulation of double-strand break repair via homologous recombination	10	2.26e-01	-2.21e-01	6.02e-01
GO:0098686 hippocampal mossy fiber to CA3 synapse	16	1.26e-01	-2.21e-01	4.64e-01
GO:0010592 positive regulation of lamellipodium assembly	10	2.28e-01	2.20e-01	6.04e-01
GO:0005540 hyaluronic acid binding	13	1.69e-01	2.20e-01	5.31e-01
GO:0006816 calcium ion transport	19	9.68e-02	2.20e-01	4.15e-01
GO:0000151 ubiquitin ligase complex	48	8.37e-03	-2.20e-01	1.40e-01
GO:0009953 dorsal/ventral pattern formation	16	1.28e-01	-2.20e-01	4.67e-01
GO:0048144 fibroblast proliferation	22	7.45e-02	2.20e-01	3.69e-01
GO:0045184 establishment of protein localization	17	1.17e-01	2.19e-01	4.51e-01
GO:0008320 protein transmembrane transporter activity	11	2.08e-01	-2.19e-01	5.83e-01
GO:0034394 protein localization to cell surface	17	1.18e-01	-2.19e-01	4.53e-01
GO:0051287 NAD binding	19	9.95e-02	2.18e-01	4.20e-01
GO:0003725 double-stranded RNA binding	44	1.24e-02	-2.18e-01	1.65e-01
GO:0030593 neutrophil chemotaxis	13	1.75e-01	2.17e-01	5.38e-01
GO:0045931 positive regulation of mitotic cell cycle	14	1.60e-01	2.17e-01	5.20e-01
GO:0005811 lipid droplet	42	1.51e-02	2.17e-01	1.87e-01
GO:0040014 regulation of multicellular organism growth	12	1.95e-01	2.16e-01	5.67e-01
GO:0001540 amyloid-beta binding	28	4.84e-02	2.16e-01	3.11e-01
GO:0003925 G protein activity	18	1.14e-01	2.15e-01	4.45e-01
GO:0019827 stem cell population maintenance	21	8.78e-02	-2.15e-01	3.95e-01
GO:0004402 histone acetyltransferase activity	11	2.17e-01	-2.15e-01	5.92e-01
GO:1990830 cellular response to leukemia inhibitory factor	66	2.62e-03	-2.14e-01	7.60e-02
GO:0030331 nuclear estrogen receptor binding	19	1.06e-01	-2.14e-01	4.30e-01
GO:0070050 neuron cellular homeostasis	14	1.65e-01	-2.14e-01	5.25e-01
GO:0006672 ceramide metabolic process	10	2.41e-01	2.14e-01	6.20e-01
GO:0035924 cellular response to vascular endothelial growth factor stimulus	16	1.39e-01	2.14e-01	4.84e-01
GO:0070373 negative regulation of ERK1 and ERK2 cascade	30	4.33e-02	-2.13e-01	3.02e-01
GO:1902018 negative regulation of cilium assembly	13	1.83e-01	-2.13e-01	5.52e-01
GO:0003899 DNA-directed 5’-3’ RNA polymerase activity	10	2.43e-01	-2.13e-01	6.22e-01
GO:0018279 protein N-linked glycosylation via asparagine	11	2.21e-01	2.13e-01	5.95e-01
GO:0071277 cellular response to calcium ion	32	3.74e-02	2.13e-01	2.78e-01
GO:0009615 response to virus	29	4.76e-02	2.13e-01	3.10e-01
GO:0140416 transcription regulator inhibitor activity	12	2.03e-01	-2.12e-01	5.77e-01
GO:0045815 transcription initiation-coupled chromatin remodeling	20	1.01e-01	-2.12e-01	4.21e-01
GO:0043122 regulation of canonical NF-kappaB signal transduction	18	1.20e-01	2.12e-01	4.55e-01
GO:0007608 sensory perception of smell	11	2.25e-01	2.12e-01	6.00e-01
GO:0005694 chromosome	76	1.45e-03	-2.11e-01	5.34e-02
GO:0070372 regulation of ERK1 and ERK2 cascade	12	2.06e-01	-2.11e-01	5.81e-01
GO:0007601 visual perception	37	2.67e-02	2.11e-01	2.41e-01
GO:0071005 U2-type precatalytic spliceosome	31	4.30e-02	-2.10e-01	3.02e-01
GO:0001046 core promoter sequence-specific DNA binding	11	2.28e-01	-2.10e-01	6.04e-01
GO:0072583 clathrin-dependent endocytosis	19	1.14e-01	2.09e-01	4.46e-01
GO:0042307 positive regulation of protein import into nucleus	25	7.04e-02	-2.09e-01	3.55e-01
GO:0010824 regulation of centrosome duplication	15	1.61e-01	-2.09e-01	5.20e-01
GO:0070006 metalloaminopeptidase activity	15	1.61e-01	2.09e-01	5.20e-01
GO:0036064 ciliary basal body	103	2.56e-04	2.09e-01	2.06e-02
GO:1905515 non-motile cilium assembly	39	2.47e-02	2.08e-01	2.33e-01
GO:0007162 negative regulation of cell adhesion	17	1.38e-01	-2.08e-01	4.84e-01
GO:0035102 PRC1 complex	12	2.15e-01	-2.07e-01	5.91e-01
GO:0097352 autophagosome maturation	23	8.73e-02	2.06e-01	3.94e-01
GO:0016973 poly(A)+ mRNA export from nucleus	13	2.00e-01	-2.05e-01	5.77e-01
GO:0030855 epithelial cell differentiation	29	5.61e-02	2.05e-01	3.28e-01
GO:0006488 dolichol-linked oligosaccharide biosynthetic process	14	1.85e-01	2.05e-01	5.55e-01
GO:0007405 neuroblast proliferation	21	1.04e-01	2.05e-01	4.30e-01
GO:0043484 regulation of RNA splicing	23	8.95e-02	-2.05e-01	3.99e-01
GO:0031175 neuron projection development	50	1.24e-02	-2.05e-01	1.65e-01
GO:0051480 regulation of cytosolic calcium ion concentration	13	2.02e-01	2.04e-01	5.77e-01
GO:0008089 anterograde axonal transport	10	2.67e-01	2.03e-01	6.50e-01
GO:0007026 negative regulation of microtubule depolymerization	17	1.49e-01	2.02e-01	5.00e-01
GO:0016491 oxidoreductase activity	46	1.78e-02	2.02e-01	1.99e-01
GO:0006891 intra-Golgi vesicle-mediated transport	19	1.27e-01	2.02e-01	4.67e-01
GO:0003714 transcription corepressor activity	101	4.72e-04	-2.02e-01	2.99e-02
GO:0007623 circadian rhythm	18	1.39e-01	2.01e-01	4.86e-01
GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity	13	2.09e-01	-2.01e-01	5.84e-01
GO:0005643 nuclear pore	33	4.62e-02	-2.01e-01	3.08e-01
GO:0004860 protein kinase inhibitor activity	19	1.31e-01	2.00e-01	4.72e-01
GO:0006979 response to oxidative stress	49	1.53e-02	2.00e-01	1.87e-01
GO:0006633 fatty acid biosynthetic process	22	1.05e-01	2.00e-01	4.30e-01
GO:0032956 regulation of actin cytoskeleton organization	37	3.61e-02	1.99e-01	2.74e-01
GO:0035115 embryonic forelimb morphogenesis	16	1.69e-01	1.98e-01	5.31e-01
GO:0007492 endoderm development	11	2.55e-01	-1.98e-01	6.37e-01
GO:0003729 mRNA binding	145	4.00e-05	-1.98e-01	5.21e-03
GO:0048812 neuron projection morphogenesis	31	5.71e-02	-1.98e-01	3.31e-01
GO:0034451 centriolar satellite	73	3.60e-03	1.97e-01	9.10e-02
GO:0001501 skeletal system development	34	4.68e-02	1.97e-01	3.09e-01
GO:0010975 regulation of neuron projection development	16	1.73e-01	1.97e-01	5.36e-01
GO:0048278 vesicle docking	13	2.20e-01	1.97e-01	5.94e-01
GO:0009982 pseudouridine synthase activity	12	2.39e-01	-1.96e-01	6.20e-01
GO:0048384 retinoic acid receptor signaling pathway	11	2.60e-01	-1.96e-01	6.45e-01
GO:0030946 protein tyrosine phosphatase activity, metal-dependent	15	1.88e-01	-1.96e-01	5.61e-01
GO:0140793 histone H2AXY142 phosphatase activity	15	1.88e-01	-1.96e-01	5.61e-01
GO:0006654 phosphatidic acid biosynthetic process	12	2.40e-01	1.96e-01	6.20e-01
GO:0050768 negative regulation of neurogenesis	10	2.84e-01	-1.96e-01	6.64e-01
GO:0005814 centriole	92	1.20e-03	1.96e-01	5.05e-02
GO:0001837 epithelial to mesenchymal transition	16	1.77e-01	1.95e-01	5.42e-01
GO:0031369 translation initiation factor binding	12	2.42e-01	-1.95e-01	6.21e-01
GO:0031573 mitotic intra-S DNA damage checkpoint signaling	11	2.63e-01	-1.95e-01	6.49e-01
GO:0007224 smoothened signaling pathway	51	1.64e-02	1.94e-01	1.92e-01
GO:0006270 DNA replication initiation	19	1.44e-01	-1.94e-01	4.96e-01
GO:0019915 lipid storage	11	2.67e-01	1.93e-01	6.50e-01
GO:0007166 cell surface receptor signaling pathway	40	3.44e-02	1.93e-01	2.72e-01
GO:0030140 trans-Golgi network transport vesicle	11	2.67e-01	-1.93e-01	6.50e-01
GO:0030742 GTP-dependent protein binding	13	2.29e-01	1.93e-01	6.04e-01
GO:0005882 intermediate filament	20	1.36e-01	-1.92e-01	4.82e-01
GO:0043425 bHLH transcription factor binding	10	2.93e-01	-1.92e-01	6.75e-01
GO:0008584 male gonad development	28	7.90e-02	1.92e-01	3.81e-01
GO:0006325 chromatin organization	66	7.23e-03	-1.91e-01	1.29e-01
GO:0010718 positive regulation of epithelial to mesenchymal transition	26	9.19e-02	-1.91e-01	4.06e-01
GO:0006338 chromatin remodeling	249	2.31e-07	-1.91e-01	5.83e-05
GO:0006368 transcription elongation by RNA polymerase II	24	1.06e-01	-1.91e-01	4.30e-01
GO:0004721 phosphoprotein phosphatase activity	21	1.31e-01	-1.90e-01	4.73e-01
GO:0001974 blood vessel remodeling	16	1.88e-01	1.90e-01	5.61e-01
GO:0140311 protein sequestering activity	18	1.63e-01	1.90e-01	5.21e-01
GO:0071479 cellular response to ionizing radiation	22	1.24e-01	-1.90e-01	4.61e-01
GO:1901223 negative regulation of non-canonical NF-kappaB signal transduction	14	2.20e-01	1.89e-01	5.94e-01
GO:0008094 ATP-dependent activity, acting on DNA	11	2.80e-01	-1.88e-01	6.64e-01
GO:0005815 microtubule organizing center	36	5.13e-02	1.88e-01	3.19e-01
GO:0034097 response to cytokine	12	2.61e-01	-1.87e-01	6.46e-01
GO:0042102 positive regulation of T cell proliferation	10	3.05e-01	-1.87e-01	6.85e-01
GO:0000266 mitochondrial fission	10	3.06e-01	1.87e-01	6.85e-01
GO:0032040 small-subunit processome	59	1.31e-02	-1.87e-01	1.70e-01
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding	13	2.44e-01	1.87e-01	6.22e-01
GO:0000987 cis-regulatory region sequence-specific DNA binding	21	1.40e-01	-1.86e-01	4.87e-01
GO:0008168 methyltransferase activity	13	2.47e-01	-1.86e-01	6.27e-01
GO:0055037 recycling endosome	56	1.65e-02	1.85e-01	1.92e-01
GO:0043153 entrainment of circadian clock by photoperiod	13	2.48e-01	-1.85e-01	6.27e-01
GO:0005721 pericentric heterochromatin	18	1.75e-01	-1.85e-01	5.38e-01
GO:0071466 cellular response to xenobiotic stimulus	25	1.10e-01	-1.85e-01	4.36e-01
GO:0001935 endothelial cell proliferation	12	2.68e-01	1.85e-01	6.50e-01
GO:0008047 enzyme activator activity	15	2.16e-01	-1.84e-01	5.92e-01
GO:0090102 cochlea development	12	2.69e-01	1.84e-01	6.50e-01
GO:0001568 blood vessel development	19	1.65e-01	1.84e-01	5.25e-01
GO:0001221 transcription coregulator binding	17	1.89e-01	-1.84e-01	5.63e-01
GO:0004896 cytokine receptor activity	19	1.66e-01	1.83e-01	5.27e-01
GO:0005771 multivesicular body	21	1.46e-01	1.83e-01	4.99e-01
GO:0042254 ribosome biogenesis	16	2.06e-01	-1.83e-01	5.83e-01
GO:0017147 Wnt-protein binding	17	1.93e-01	1.82e-01	5.66e-01
GO:0015026 coreceptor activity	13	2.55e-01	1.82e-01	6.37e-01
GO:0007018 microtubule-based movement	40	4.60e-02	1.82e-01	3.08e-01
GO:0051781 positive regulation of cell division	13	2.55e-01	1.82e-01	6.37e-01
GO:0008380 RNA splicing	47	3.08e-02	-1.82e-01	2.61e-01
GO:0046849 bone remodeling	10	3.19e-01	-1.82e-01	6.98e-01
GO:0035249 synaptic transmission, glutamatergic	16	2.08e-01	1.82e-01	5.83e-01
GO:0044782 cilium organization	13	2.57e-01	1.82e-01	6.39e-01
GO:0042327 positive regulation of phosphorylation	12	2.76e-01	1.82e-01	6.64e-01
GO:0016853 isomerase activity	19	1.71e-01	-1.81e-01	5.34e-01
GO:0000974 Prp19 complex	10	3.21e-01	-1.81e-01	6.99e-01
GO:0038061 non-canonical NF-kappaB signal transduction	11	2.98e-01	-1.81e-01	6.80e-01
GO:0031466 Cul5-RING ubiquitin ligase complex	11	2.98e-01	1.81e-01	6.80e-01
GO:0030057 desmosome	11	2.98e-01	-1.81e-01	6.80e-01
GO:0004386 helicase activity	40	4.76e-02	-1.81e-01	3.10e-01
GO:0070628 proteasome binding	13	2.61e-01	-1.80e-01	6.46e-01
GO:0090543 Flemming body	14	2.44e-01	1.80e-01	6.22e-01
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding	41	4.68e-02	1.80e-01	3.09e-01
GO:0000070 mitotic sister chromatid segregation	18	1.90e-01	1.78e-01	5.63e-01
GO:0032743 positive regulation of interleukin-2 production	16	2.17e-01	1.78e-01	5.92e-01
GO:0060382 regulation of DNA strand elongation	10	3.29e-01	-1.78e-01	7.08e-01
GO:0032266 phosphatidylinositol-3-phosphate binding	32	8.16e-02	1.78e-01	3.86e-01
GO:0000132 establishment of mitotic spindle orientation	26	1.17e-01	1.78e-01	4.50e-01
GO:0045454 cell redox homeostasis	20	1.69e-01	1.78e-01	5.31e-01
GO:0045648 positive regulation of erythrocyte differentiation	18	1.92e-01	-1.78e-01	5.66e-01
GO:0004622 lysophospholipase activity	10	3.31e-01	1.77e-01	7.12e-01
GO:0032729 positive regulation of type II interferon production	22	1.50e-01	1.77e-01	5.02e-01
GO:0043296 apical junction complex	10	3.32e-01	-1.77e-01	7.12e-01
GO:0048854 brain morphogenesis	14	2.51e-01	1.77e-01	6.33e-01
GO:0097150 neuronal stem cell population maintenance	18	1.93e-01	1.77e-01	5.66e-01
GO:0044183 protein folding chaperone	21	1.62e-01	-1.76e-01	5.20e-01
GO:0007338 single fertilization	20	1.72e-01	1.76e-01	5.36e-01
GO:0005762 mitochondrial large ribosomal subunit	38	6.02e-02	1.76e-01	3.36e-01
GO:0032722 positive regulation of chemokine production	11	3.12e-01	1.76e-01	6.89e-01
GO:0035613 RNA stem-loop binding	11	3.12e-01	-1.76e-01	6.89e-01
GO:1904262 negative regulation of TORC1 signaling	28	1.08e-01	1.75e-01	4.34e-01
GO:0006622 protein targeting to lysosome	15	2.41e-01	1.75e-01	6.20e-01
GO:0006376 mRNA splice site recognition	12	2.94e-01	-1.75e-01	6.76e-01
GO:0046854 phosphatidylinositol phosphate biosynthetic process	18	2.00e-01	-1.75e-01	5.77e-01
GO:0006487 protein N-linked glycosylation	30	9.80e-02	1.75e-01	4.18e-01
GO:0000146 microfilament motor activity	19	1.88e-01	-1.74e-01	5.61e-01
GO:2000378 negative regulation of reactive oxygen species metabolic process	10	3.40e-01	1.74e-01	7.18e-01
GO:0007064 mitotic sister chromatid cohesion	10	3.40e-01	1.74e-01	7.18e-01
GO:0035064 methylated histone binding	42	5.23e-02	-1.73e-01	3.19e-01
GO:0030163 protein catabolic process	31	9.54e-02	1.73e-01	4.12e-01
GO:0035198 miRNA binding	20	1.80e-01	-1.73e-01	5.49e-01
GO:0051592 response to calcium ion	20	1.80e-01	1.73e-01	5.49e-01
GO:0031072 heat shock protein binding	27	1.21e-01	-1.73e-01	4.55e-01
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway	13	2.85e-01	-1.71e-01	6.64e-01
GO:0061351 neural precursor cell proliferation	14	2.67e-01	-1.71e-01	6.50e-01
GO:0007097 nuclear migration	15	2.53e-01	1.71e-01	6.35e-01
GO:0032757 positive regulation of interleukin-8 production	17	2.24e-01	1.70e-01	5.99e-01
GO:0005637 nuclear inner membrane	24	1.49e-01	1.70e-01	5.00e-01
GO:0046329 negative regulation of JNK cascade	12	3.09e-01	1.70e-01	6.86e-01
GO:2000042 negative regulation of double-strand break repair via homologous recombination	16	2.41e-01	-1.69e-01	6.20e-01
GO:0033017 sarcoplasmic reticulum membrane	10	3.54e-01	-1.69e-01	7.30e-01
GO:0061024 membrane organization	13	2.91e-01	1.69e-01	6.73e-01
GO:0050681 nuclear androgen receptor binding	16	2.41e-01	-1.69e-01	6.20e-01
GO:0001650 fibrillar center	101	3.33e-03	-1.69e-01	9.06e-02
GO:0004521 RNA endonuclease activity	20	1.90e-01	1.69e-01	5.64e-01
GO:0032760 positive regulation of tumor necrosis factor production	33	9.28e-02	1.69e-01	4.07e-01
GO:0006275 regulation of DNA replication	24	1.53e-01	-1.69e-01	5.05e-01
GO:0043536 positive regulation of blood vessel endothelial cell migration	18	2.16e-01	1.68e-01	5.92e-01
GO:0032467 positive regulation of cytokinesis	14	2.75e-01	1.68e-01	6.63e-01
GO:0001894 tissue homeostasis	13	2.94e-01	-1.68e-01	6.76e-01
GO:0007098 centrosome cycle	17	2.31e-01	1.68e-01	6.06e-01
GO:0030488 tRNA methylation	20	1.95e-01	-1.68e-01	5.67e-01
GO:0030837 negative regulation of actin filament polymerization	14	2.78e-01	1.67e-01	6.64e-01
GO:0045202 synapse	163	2.34e-04	1.67e-01	2.06e-02
GO:0071013 catalytic step 2 spliceosome	52	3.71e-02	-1.67e-01	2.77e-01
GO:0031468 nuclear membrane reassembly	11	3.38e-01	1.67e-01	7.17e-01
GO:1905168 positive regulation of double-strand break repair via homologous recombination	25	1.49e-01	-1.67e-01	5.00e-01
GO:0071300 cellular response to retinoic acid	17	2.35e-01	-1.66e-01	6.13e-01
GO:0045766 positive regulation of angiogenesis	53	3.64e-02	1.66e-01	2.75e-01
GO:0036464 cytoplasmic ribonucleoprotein granule	36	8.45e-02	1.66e-01	3.88e-01
GO:0015459 potassium channel regulator activity	14	2.83e-01	-1.66e-01	6.64e-01
GO:0032715 negative regulation of interleukin-6 production	14	2.83e-01	-1.66e-01	6.64e-01
GO:0007095 mitotic G2 DNA damage checkpoint signaling	30	1.17e-01	-1.66e-01	4.50e-01
GO:0001508 action potential	11	3.42e-01	-1.66e-01	7.19e-01
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis	14	2.85e-01	1.65e-01	6.64e-01
GO:0014704 intercalated disc	13	3.03e-01	1.65e-01	6.84e-01
GO:0046856 phosphatidylinositol dephosphorylation	26	1.46e-01	-1.65e-01	4.99e-01
GO:0033627 cell adhesion mediated by integrin	23	1.72e-01	1.65e-01	5.36e-01
GO:0048010 vascular endothelial growth factor receptor signaling pathway	13	3.04e-01	-1.65e-01	6.84e-01
GO:0005581 collagen trimer	20	2.04e-01	1.64e-01	5.77e-01
GO:0070498 interleukin-1-mediated signaling pathway	11	3.46e-01	1.64e-01	7.24e-01
GO:0098685 Schaffer collateral - CA1 synapse	44	6.00e-02	1.64e-01	3.36e-01
GO:0017124 SH3 domain binding	43	6.31e-02	1.64e-01	3.44e-01
GO:0003333 amino acid transmembrane transport	10	3.70e-01	-1.64e-01	7.41e-01
GO:0030509 BMP signaling pathway	38	8.10e-02	-1.64e-01	3.84e-01
GO:0097431 mitotic spindle pole	27	1.42e-01	-1.63e-01	4.90e-01
GO:0033192 calmodulin-dependent protein phosphatase activity	16	2.59e-01	-1.63e-01	6.44e-01
GO:0045732 positive regulation of protein catabolic process	47	5.35e-02	1.63e-01	3.24e-01
GO:0098793 presynapse	63	2.59e-02	1.62e-01	2.38e-01
GO:0031334 positive regulation of protein-containing complex assembly	17	2.47e-01	1.62e-01	6.27e-01
GO:0043679 axon terminus	17	2.47e-01	-1.62e-01	6.27e-01
GO:0030036 actin cytoskeleton organization	107	3.99e-03	-1.61e-01	9.40e-02
GO:0000045 autophagosome assembly	52	4.44e-02	1.61e-01	3.06e-01
GO:0001707 mesoderm formation	15	2.81e-01	-1.61e-01	6.64e-01
GO:0006281 DNA repair	95	6.82e-03	-1.61e-01	1.29e-01
GO:0042277 peptide binding	10	3.79e-01	-1.61e-01	7.45e-01
GO:0010608 post-transcriptional regulation of gene expression	11	3.57e-01	-1.61e-01	7.31e-01
GO:0005828 kinetochore microtubule	10	3.80e-01	1.60e-01	7.45e-01
GO:0072593 reactive oxygen species metabolic process	15	2.82e-01	1.60e-01	6.64e-01
GO:0097194 execution phase of apoptosis	10	3.82e-01	1.60e-01	7.47e-01
GO:0003151 outflow tract morphogenesis	19	2.28e-01	1.60e-01	6.04e-01
GO:0090443 FAR/SIN/STRIPAK complex	12	3.38e-01	1.60e-01	7.17e-01
GO:0042273 ribosomal large subunit biogenesis	22	1.97e-01	-1.59e-01	5.73e-01
GO:0007052 mitotic spindle organization	34	1.10e-01	1.59e-01	4.36e-01
GO:0030286 dynein complex	10	3.85e-01	1.59e-01	7.50e-01
GO:0006397 mRNA processing	72	2.05e-02	-1.58e-01	2.21e-01
GO:0016485 protein processing	40	8.38e-02	1.58e-01	3.88e-01
GO:0010976 positive regulation of neuron projection development	30	1.34e-01	1.58e-01	4.79e-01
GO:0005769 early endosome	141	1.24e-03	1.58e-01	5.05e-02
GO:0034446 substrate adhesion-dependent cell spreading	34	1.12e-01	-1.57e-01	4.40e-01
GO:0072089 stem cell proliferation	21	2.13e-01	1.57e-01	5.88e-01
GO:0007214 gamma-aminobutyric acid signaling pathway	11	3.67e-01	1.57e-01	7.41e-01
GO:0016226 iron-sulfur cluster assembly	17	2.62e-01	1.57e-01	6.48e-01
GO:0006805 xenobiotic metabolic process	17	2.64e-01	1.57e-01	6.49e-01
GO:0030833 regulation of actin filament polymerization	21	2.15e-01	1.56e-01	5.91e-01
GO:0048706 embryonic skeletal system development	16	2.79e-01	1.56e-01	6.64e-01
GO:0042593 glucose homeostasis	42	8.04e-02	1.56e-01	3.82e-01
GO:0000775 chromosome, centromeric region	31	1.33e-01	1.56e-01	4.75e-01
GO:0045335 phagocytic vesicle	36	1.06e-01	1.56e-01	4.30e-01
GO:0007131 reciprocal meiotic recombination	12	3.52e-01	1.55e-01	7.29e-01
GO:0008053 mitochondrial fusion	17	2.68e-01	-1.55e-01	6.50e-01
GO:0051056 regulation of small GTPase mediated signal transduction	16	2.83e-01	1.55e-01	6.64e-01
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway	26	1.73e-01	1.54e-01	5.36e-01
GO:0034332 adherens junction organization	11	3.76e-01	1.54e-01	7.45e-01
GO:0046718 symbiont entry into host cell	22	2.11e-01	-1.54e-01	5.87e-01
GO:0048009 insulin-like growth factor receptor signaling pathway	31	1.38e-01	-1.54e-01	4.84e-01
GO:0005245 voltage-gated calcium channel activity	11	3.78e-01	1.53e-01	7.45e-01
GO:0070830 bicellular tight junction assembly	19	2.47e-01	1.53e-01	6.27e-01
GO:0045669 positive regulation of osteoblast differentiation	37	1.07e-01	-1.53e-01	4.32e-01
GO:0032012 regulation of ARF protein signal transduction	14	3.22e-01	1.53e-01	6.99e-01
GO:0033962 P-body assembly	14	3.23e-01	-1.52e-01	6.99e-01
GO:0005764 lysosome	133	2.46e-03	1.52e-01	7.37e-02
GO:0045595 regulation of cell differentiation	13	3.42e-01	1.52e-01	7.19e-01
GO:0071944 cell periphery	12	3.63e-01	1.52e-01	7.37e-01
GO:0009966 regulation of signal transduction	38	1.06e-01	-1.52e-01	4.30e-01
GO:0046488 phosphatidylinositol metabolic process	13	3.45e-01	-1.51e-01	7.22e-01
GO:0050808 synapse organization	17	2.80e-01	-1.51e-01	6.64e-01
GO:0008305 integrin complex	18	2.66e-01	1.51e-01	6.50e-01
GO:0009653 anatomical structure morphogenesis	22	2.20e-01	-1.51e-01	5.94e-01
GO:0019221 cytokine-mediated signaling pathway	44	8.32e-02	1.51e-01	3.88e-01
GO:0005975 carbohydrate metabolic process	49	6.77e-02	1.51e-01	3.47e-01
GO:0006457 protein folding	81	1.94e-02	-1.50e-01	2.13e-01
GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site	16	2.99e-01	1.50e-01	6.80e-01
GO:0048026 positive regulation of mRNA splicing, via spliceosome	12	3.69e-01	-1.50e-01	7.41e-01
GO:0060271 cilium assembly	125	3.90e-03	1.50e-01	9.40e-02
GO:0006935 chemotaxis	14	3.33e-01	1.50e-01	7.12e-01
GO:0021915 neural tube development	16	3.00e-01	1.50e-01	6.82e-01
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity	14	3.33e-01	-1.50e-01	7.12e-01
GO:0030968 endoplasmic reticulum unfolded protein response	30	1.57e-01	1.49e-01	5.14e-01
GO:0031333 negative regulation of protein-containing complex assembly	16	3.02e-01	1.49e-01	6.83e-01
GO:0150052 regulation of postsynapse assembly	13	3.52e-01	-1.49e-01	7.29e-01
GO:0034220 monoatomic ion transmembrane transport	19	2.62e-01	1.49e-01	6.48e-01
GO:0000228 nuclear chromosome	13	3.55e-01	-1.48e-01	7.30e-01
GO:0004435 phosphatidylinositol phospholipase C activity	12	3.74e-01	1.48e-01	7.45e-01
GO:0016740 transferase activity	23	2.20e-01	-1.48e-01	5.95e-01
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand	12	3.76e-01	-1.48e-01	7.45e-01
GO:0071480 cellular response to gamma radiation	14	3.39e-01	-1.48e-01	7.18e-01
GO:0005385 zinc ion transmembrane transporter activity	15	3.23e-01	-1.47e-01	6.99e-01
GO:0070371 ERK1 and ERK2 cascade	20	2.54e-01	1.47e-01	6.36e-01
GO:0048008 platelet-derived growth factor receptor signaling pathway	17	2.93e-01	-1.47e-01	6.75e-01
GO:0007129 homologous chromosome pairing at meiosis	13	3.58e-01	-1.47e-01	7.32e-01
GO:0000794 condensed nuclear chromosome	20	2.54e-01	1.47e-01	6.36e-01
GO:0001558 regulation of cell growth	24	2.12e-01	-1.47e-01	5.87e-01
GO:0008237 metallopeptidase activity	12	3.77e-01	1.47e-01	7.45e-01
GO:0005871 kinesin complex	22	2.33e-01	1.47e-01	6.10e-01
GO:0040018 positive regulation of multicellular organism growth	16	3.09e-01	-1.47e-01	6.86e-01
GO:0003676 nucleic acid binding	106	9.22e-03	-1.47e-01	1.47e-01
GO:0009267 cellular response to starvation	48	7.95e-02	1.46e-01	3.82e-01
GO:0031490 chromatin DNA binding	41	1.05e-01	-1.46e-01	4.30e-01
GO:0043495 protein-membrane adaptor activity	17	2.97e-01	1.46e-01	6.79e-01
GO:0006261 DNA-templated DNA replication	18	2.83e-01	-1.46e-01	6.64e-01
GO:0086091 regulation of heart rate by cardiac conduction	18	2.83e-01	-1.46e-01	6.64e-01
GO:0001782 B cell homeostasis	12	3.83e-01	-1.45e-01	7.49e-01
GO:0015813 L-glutamate transmembrane transport	11	4.04e-01	-1.45e-01	7.62e-01
GO:0019904 protein domain specific binding	104	1.06e-02	1.45e-01	1.56e-01
GO:0000086 G2/M transition of mitotic cell cycle	25	2.09e-01	1.45e-01	5.84e-01
GO:0009410 response to xenobiotic stimulus	47	8.57e-02	-1.45e-01	3.88e-01
GO:0015485 cholesterol binding	28	1.85e-01	1.45e-01	5.55e-01
GO:0051497 negative regulation of stress fiber assembly	18	2.88e-01	1.45e-01	6.68e-01
GO:0034244 negative regulation of transcription elongation by RNA polymerase II	13	3.68e-01	1.44e-01	7.41e-01
GO:0098609 cell-cell adhesion	82	2.44e-02	-1.44e-01	2.33e-01
GO:0010494 cytoplasmic stress granule	58	5.82e-02	-1.44e-01	3.35e-01
GO:2000811 negative regulation of anoikis	10	4.31e-01	1.44e-01	7.78e-01
GO:0071320 cellular response to cAMP	18	2.91e-01	1.44e-01	6.73e-01
GO:0032570 response to progesterone	13	3.69e-01	-1.44e-01	7.41e-01
GO:0034599 cellular response to oxidative stress	44	9.97e-02	1.44e-01	4.20e-01
GO:0006612 protein targeting to membrane	24	2.24e-01	-1.43e-01	5.99e-01
GO:0071816 tail-anchored membrane protein insertion into ER membrane	10	4.33e-01	1.43e-01	7.78e-01
GO:0035176 social behavior	16	3.21e-01	1.43e-01	6.99e-01
GO:0000781 chromosome, telomeric region	75	3.22e-02	-1.43e-01	2.63e-01
GO:0005198 structural molecule activity	37	1.32e-01	1.43e-01	4.74e-01
GO:0042098 T cell proliferation	16	3.23e-01	-1.43e-01	6.99e-01
GO:0048147 negative regulation of fibroblast proliferation	14	3.55e-01	-1.43e-01	7.30e-01
GO:0061631 ubiquitin conjugating enzyme activity	24	2.27e-01	1.43e-01	6.04e-01
GO:0032456 endocytic recycling	42	1.11e-01	1.42e-01	4.37e-01
GO:0004857 enzyme inhibitor activity	12	3.94e-01	-1.42e-01	7.54e-01
GO:0032755 positive regulation of interleukin-6 production	32	1.65e-01	1.42e-01	5.24e-01
GO:0005681 spliceosomal complex	43	1.08e-01	-1.42e-01	4.34e-01
GO:0090314 positive regulation of protein targeting to membrane	12	3.96e-01	1.42e-01	7.54e-01
GO:0000145 exocyst	11	4.17e-01	-1.41e-01	7.72e-01
GO:0042100 B cell proliferation	14	3.61e-01	1.41e-01	7.34e-01
GO:0098982 GABA-ergic synapse	30	1.81e-01	1.41e-01	5.49e-01
GO:0016605 PML body	61	5.69e-02	-1.41e-01	3.31e-01
GO:0048513 animal organ development	11	4.19e-01	1.41e-01	7.72e-01
GO:0006898 receptor-mediated endocytosis	23	2.44e-01	1.41e-01	6.22e-01
GO:0005005 transmembrane-ephrin receptor activity	14	3.63e-01	-1.40e-01	7.37e-01
GO:0007004 telomere maintenance via telomerase	11	4.21e-01	-1.40e-01	7.73e-01
GO:0060038 cardiac muscle cell proliferation	12	4.03e-01	1.39e-01	7.62e-01
GO:0046966 nuclear thyroid hormone receptor binding	15	3.51e-01	-1.39e-01	7.29e-01
GO:0005930 axoneme	48	9.67e-02	1.39e-01	4.15e-01
GO:0005788 endoplasmic reticulum lumen	40	1.30e-01	-1.38e-01	4.70e-01
GO:0035725 sodium ion transmembrane transport	48	9.72e-02	1.38e-01	4.15e-01
GO:0030054 cell junction	52	8.57e-02	-1.38e-01	3.88e-01
GO:0101031 protein folding chaperone complex	18	3.11e-01	-1.38e-01	6.88e-01
GO:0006511 ubiquitin-dependent protein catabolic process	117	1.02e-02	-1.38e-01	1.51e-01
GO:0030317 flagellated sperm motility	28	2.09e-01	1.37e-01	5.83e-01
GO:0006302 double-strand break repair	45	1.11e-01	-1.37e-01	4.37e-01
GO:0043565 sequence-specific DNA binding	56	7.60e-02	-1.37e-01	3.72e-01
GO:0030496 midbody	100	1.80e-02	1.37e-01	2.00e-01
GO:1904115 axon cytoplasm	25	2.36e-01	1.37e-01	6.15e-01
GO:0003774 cytoskeletal motor activity	13	3.93e-01	1.37e-01	7.54e-01
GO:0070403 NAD+ binding	11	4.33e-01	1.36e-01	7.78e-01
GO:0050729 positive regulation of inflammatory response	22	2.68e-01	1.36e-01	6.50e-01
GO:0019901 protein kinase binding	236	3.23e-04	1.36e-01	2.38e-02
GO:0042572 retinol metabolic process	12	4.14e-01	1.36e-01	7.72e-01
GO:0045787 positive regulation of cell cycle	13	3.96e-01	1.36e-01	7.54e-01
GO:0042632 cholesterol homeostasis	38	1.49e-01	1.35e-01	5.00e-01
GO:0034198 cellular response to amino acid starvation	31	1.93e-01	1.35e-01	5.66e-01
GO:0045821 positive regulation of glycolytic process	10	4.60e-01	1.35e-01	7.89e-01
GO:0042393 histone binding	94	2.44e-02	-1.35e-01	2.33e-01
GO:0010761 fibroblast migration	10	4.62e-01	1.34e-01	7.91e-01
GO:0004693 cyclin-dependent protein serine/threonine kinase activity	10	4.62e-01	1.34e-01	7.91e-01
GO:0004715 non-membrane spanning protein tyrosine kinase activity	20	2.99e-01	1.34e-01	6.80e-01
GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process	14	3.86e-01	1.34e-01	7.50e-01
GO:0006914 autophagy	44	1.25e-01	1.34e-01	4.62e-01
GO:0006268 DNA unwinding involved in DNA replication	14	3.86e-01	-1.34e-01	7.50e-01
GO:0006468 protein phosphorylation	12	4.23e-01	-1.34e-01	7.73e-01
GO:0005730 nucleolus	443	1.66e-06	-1.33e-01	3.68e-04
GO:0005669 transcription factor TFIID complex	22	2.80e-01	-1.33e-01	6.64e-01
GO:0043197 dendritic spine	46	1.20e-01	1.33e-01	4.55e-01
GO:0046907 intracellular transport	14	3.92e-01	1.32e-01	7.54e-01
GO:0042274 ribosomal small subunit biogenesis	44	1.29e-01	-1.32e-01	4.70e-01
GO:0016887 ATP hydrolysis activity	216	8.45e-04	-1.32e-01	3.73e-02
GO:0046627 negative regulation of insulin receptor signaling pathway	16	3.61e-01	1.32e-01	7.34e-01
GO:0016581 NuRD complex	10	4.70e-01	-1.32e-01	7.92e-01
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules	39	1.54e-01	-1.32e-01	5.08e-01
GO:0006367 transcription initiation at RNA polymerase II promoter	20	3.08e-01	-1.32e-01	6.86e-01
GO:0005009 insulin receptor activity	14	3.96e-01	-1.31e-01	7.54e-01
GO:0071364 cellular response to epidermal growth factor stimulus	19	3.23e-01	1.31e-01	6.99e-01
GO:0005164 tumor necrosis factor receptor binding	13	4.14e-01	1.31e-01	7.72e-01
GO:0071889 14-3-3 protein binding	15	3.81e-01	-1.31e-01	7.47e-01
GO:0090307 mitotic spindle assembly	30	2.16e-01	-1.31e-01	5.92e-01
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	13	4.15e-01	1.31e-01	7.72e-01
GO:0030155 regulation of cell adhesion	18	3.38e-01	-1.30e-01	7.17e-01
GO:0042789 mRNA transcription by RNA polymerase II	26	2.50e-01	-1.30e-01	6.31e-01
GO:0009749 response to glucose	14	3.99e-01	-1.30e-01	7.57e-01
GO:0070536 protein K63-linked deubiquitination	16	3.69e-01	-1.30e-01	7.41e-01
GO:0033209 tumor necrosis factor-mediated signaling pathway	15	3.85e-01	-1.30e-01	7.50e-01
GO:0000922 spindle pole	69	6.34e-02	1.29e-01	3.44e-01
GO:0006695 cholesterol biosynthetic process	16	3.71e-01	1.29e-01	7.41e-01
GO:0070161 anchoring junction	17	3.57e-01	-1.29e-01	7.31e-01
GO:0050661 NADP binding	15	3.87e-01	1.29e-01	7.51e-01
GO:0005515 protein binding	90	3.48e-02	-1.29e-01	2.72e-01
GO:0019888 protein phosphatase regulator activity	16	3.73e-01	-1.29e-01	7.45e-01
GO:0007411 axon guidance	77	5.11e-02	-1.29e-01	3.19e-01
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway	13	4.23e-01	-1.29e-01	7.73e-01
GO:0008143 poly(A) binding	13	4.24e-01	1.28e-01	7.73e-01
GO:1902894 negative regulation of miRNA transcription	12	4.43e-01	-1.28e-01	7.82e-01
GO:0055038 recycling endosome membrane	43	1.49e-01	1.27e-01	5.00e-01
GO:0045600 positive regulation of fat cell differentiation	21	3.13e-01	1.27e-01	6.89e-01
GO:0090303 positive regulation of wound healing	11	4.65e-01	1.27e-01	7.92e-01
GO:0008180 COP9 signalosome	21	3.14e-01	1.27e-01	6.90e-01
GO:0034450 ubiquitin-ubiquitin ligase activity	12	4.47e-01	1.27e-01	7.83e-01
GO:0007266 Rho protein signal transduction	33	2.08e-01	1.27e-01	5.83e-01
GO:0043138 3’-5’ DNA helicase activity	10	4.89e-01	-1.26e-01	8.02e-01
GO:0012507 ER to Golgi transport vesicle membrane	11	4.69e-01	1.26e-01	7.92e-01
GO:0051402 neuron apoptotic process	42	1.58e-01	1.26e-01	5.16e-01
GO:0046677 response to antibiotic	13	4.31e-01	1.26e-01	7.78e-01
GO:0016607 nuclear speck	241	7.95e-04	-1.26e-01	3.60e-02
GO:0035329 hippo signaling	18	3.56e-01	1.26e-01	7.31e-01
GO:0061157 mRNA destabilization	12	4.51e-01	-1.26e-01	7.85e-01
GO:0008360 regulation of cell shape	60	9.43e-02	-1.25e-01	4.10e-01
GO:0004879 nuclear receptor activity	38	1.83e-01	1.25e-01	5.52e-01
GO:0032993 protein-DNA complex	21	3.23e-01	1.25e-01	6.99e-01
GO:0008023 transcription elongation factor complex	14	4.20e-01	-1.24e-01	7.73e-01
GO:0042626 ATPase-coupled transmembrane transporter activity	17	3.75e-01	1.24e-01	7.45e-01
GO:0005782 peroxisomal matrix	10	4.96e-01	1.24e-01	8.02e-01
GO:0032465 regulation of cytokinesis	23	3.02e-01	1.24e-01	6.84e-01
GO:0070131 positive regulation of mitochondrial translation	10	4.96e-01	-1.24e-01	8.02e-01
GO:0070301 cellular response to hydrogen peroxide	23	3.03e-01	-1.24e-01	6.84e-01
GO:0046513 ceramide biosynthetic process	19	3.49e-01	-1.24e-01	7.28e-01
GO:0099171 presynaptic modulation of chemical synaptic transmission	11	4.77e-01	1.24e-01	7.99e-01
GO:0006886 intracellular protein transport	160	7.06e-03	1.24e-01	1.29e-01
GO:0008201 heparin binding	56	1.10e-01	1.24e-01	4.36e-01
GO:0030234 enzyme regulator activity	14	4.24e-01	1.23e-01	7.73e-01
GO:0050769 positive regulation of neurogenesis	12	4.60e-01	-1.23e-01	7.89e-01
GO:0030198 extracellular matrix organization	77	6.20e-02	1.23e-01	3.42e-01
GO:0045724 positive regulation of cilium assembly	13	4.43e-01	1.23e-01	7.82e-01
GO:0007611 learning or memory	15	4.11e-01	1.23e-01	7.69e-01
GO:0051085 chaperone cofactor-dependent protein refolding	23	3.09e-01	-1.23e-01	6.86e-01
GO:0007030 Golgi organization	63	9.42e-02	1.22e-01	4.10e-01
GO:0007628 adult walking behavior	13	4.47e-01	-1.22e-01	7.83e-01
GO:0005743 mitochondrial inner membrane	180	4.91e-03	1.22e-01	1.07e-01
GO:0000398 mRNA splicing, via spliceosome	87	5.01e-02	-1.22e-01	3.16e-01
GO:0019894 kinesin binding	22	3.24e-01	1.22e-01	6.99e-01
GO:0005010 insulin-like growth factor receptor activity	13	4.48e-01	-1.21e-01	7.84e-01
GO:0048568 embryonic organ development	15	4.16e-01	1.21e-01	7.72e-01
GO:0015629 actin cytoskeleton	115	2.49e-02	-1.21e-01	2.33e-01
GO:0045665 negative regulation of neuron differentiation	25	2.94e-01	-1.21e-01	6.76e-01
GO:0005008 hepatocyte growth factor receptor activity	13	4.50e-01	-1.21e-01	7.84e-01
GO:0043596 nuclear replication fork	10	5.08e-01	1.21e-01	8.08e-01
GO:0042645 mitochondrial nucleoid	37	2.03e-01	-1.21e-01	5.77e-01
GO:0005759 mitochondrial matrix	119	2.30e-02	1.21e-01	2.30e-01
GO:0060218 hematopoietic stem cell differentiation	11	4.88e-01	1.21e-01	8.02e-01
GO:0000785 chromatin	241	1.31e-03	-1.21e-01	5.15e-02
GO:0016192 vesicle-mediated transport	101	3.67e-02	1.20e-01	2.76e-01
GO:0005801 cis-Golgi network	28	2.70e-01	1.20e-01	6.53e-01
GO:0050750 low-density lipoprotein particle receptor binding	12	4.70e-01	-1.20e-01	7.92e-01
GO:0002102 podosome	19	3.64e-01	1.20e-01	7.37e-01
GO:0071011 precatalytic spliceosome	12	4.71e-01	1.20e-01	7.92e-01
GO:0003723 RNA binding	372	7.50e-05	-1.20e-01	8.28e-03
GO:0003682 chromatin binding	238	1.50e-03	-1.20e-01	5.42e-02
GO:1990904 ribonucleoprotein complex	104	3.52e-02	1.20e-01	2.72e-01
GO:0001937 negative regulation of endothelial cell proliferation	12	4.73e-01	-1.20e-01	7.94e-01
GO:0010506 regulation of autophagy	26	2.91e-01	1.20e-01	6.73e-01
GO:0050679 positive regulation of epithelial cell proliferation	20	3.55e-01	-1.19e-01	7.30e-01
GO:1902476 chloride transmembrane transport	39	1.97e-01	1.19e-01	5.73e-01
GO:0043022 ribosome binding	46	1.62e-01	-1.19e-01	5.20e-01
GO:0045879 negative regulation of smoothened signaling pathway	16	4.10e-01	1.19e-01	7.69e-01
GO:0008289 lipid binding	44	1.72e-01	1.19e-01	5.36e-01
GO:0033344 cholesterol efflux	11	4.96e-01	-1.19e-01	8.02e-01
GO:0006986 response to unfolded protein	12	4.78e-01	-1.18e-01	7.99e-01
GO:0045171 intercellular bridge	55	1.30e-01	1.18e-01	4.70e-01
GO:0006897 endocytosis	92	5.04e-02	1.18e-01	3.16e-01
GO:0008283 cell population proliferation	65	1.00e-01	-1.18e-01	4.20e-01
GO:0030150 protein import into mitochondrial matrix	12	4.80e-01	1.18e-01	8.00e-01
GO:0006413 translational initiation	30	2.65e-01	-1.18e-01	6.50e-01
GO:0016787 hydrolase activity	108	3.54e-02	-1.17e-01	2.72e-01
GO:0008198 ferrous iron binding	12	4.82e-01	-1.17e-01	8.01e-01
GO:0042169 SH2 domain binding	20	3.64e-01	1.17e-01	7.37e-01
GO:0070412 R-SMAD binding	13	4.65e-01	-1.17e-01	7.92e-01
GO:0032007 negative regulation of TOR signaling	18	3.91e-01	1.17e-01	7.54e-01
GO:0006509 membrane protein ectodomain proteolysis	15	4.34e-01	-1.17e-01	7.78e-01
GO:0017116 single-stranded DNA helicase activity	16	4.19e-01	-1.17e-01	7.72e-01
GO:0016567 protein ubiquitination	155	1.24e-02	-1.17e-01	1.65e-01
GO:0060828 regulation of canonical Wnt signaling pathway	18	3.92e-01	-1.16e-01	7.54e-01
GO:0005109 frizzled binding	18	3.94e-01	1.16e-01	7.54e-01
GO:0006629 lipid metabolic process	52	1.48e-01	1.16e-01	5.00e-01
GO:0071539 protein localization to centrosome	20	3.69e-01	1.16e-01	7.41e-01
GO:0015297 antiporter activity	18	3.94e-01	1.16e-01	7.54e-01
GO:0010719 negative regulation of epithelial to mesenchymal transition	16	4.23e-01	-1.16e-01	7.73e-01
GO:0032039 integrator complex	15	4.38e-01	-1.16e-01	7.80e-01
GO:0019933 cAMP-mediated signaling	13	4.71e-01	1.16e-01	7.92e-01
GO:0051321 meiotic cell cycle	21	3.60e-01	-1.15e-01	7.34e-01
GO:0019706 protein-cysteine S-palmitoyltransferase activity	17	4.11e-01	-1.15e-01	7.69e-01
GO:0030426 growth cone	41	2.03e-01	-1.15e-01	5.77e-01
GO:0051131 chaperone-mediated protein complex assembly	14	4.56e-01	-1.15e-01	7.86e-01
GO:0008327 methyl-CpG binding	16	4.26e-01	-1.15e-01	7.74e-01
GO:0030010 establishment of cell polarity	18	3.99e-01	1.15e-01	7.57e-01
GO:0032259 methylation	76	8.46e-02	-1.15e-01	3.88e-01
GO:0070063 RNA polymerase binding	12	4.92e-01	1.14e-01	8.02e-01
GO:0001618 virus receptor activity	10	5.32e-01	-1.14e-01	8.27e-01
GO:0140693 molecular condensate scaffold activity	24	3.33e-01	-1.14e-01	7.12e-01
GO:0005615 extracellular space	397	1.05e-04	1.14e-01	1.10e-02
GO:0010212 response to ionizing radiation	24	3.34e-01	-1.14e-01	7.13e-01
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway	19	3.91e-01	-1.14e-01	7.54e-01
GO:0008017 microtubule binding	153	1.55e-02	1.14e-01	1.88e-01
GO:0030670 phagocytic vesicle membrane	19	3.92e-01	1.13e-01	7.54e-01
GO:0120009 intermembrane lipid transfer	16	4.33e-01	1.13e-01	7.78e-01
GO:0031410 cytoplasmic vesicle	106	4.47e-02	1.13e-01	3.06e-01
GO:0071260 cellular response to mechanical stimulus	23	3.48e-01	1.13e-01	7.27e-01
GO:0001917 photoreceptor inner segment	23	3.49e-01	1.13e-01	7.28e-01
GO:0001708 cell fate specification	12	4.99e-01	-1.13e-01	8.03e-01
GO:0051290 protein heterotetramerization	10	5.38e-01	-1.13e-01	8.29e-01
GO:0050770 regulation of axonogenesis	13	4.82e-01	-1.13e-01	8.01e-01
GO:0140374 antiviral innate immune response	20	3.84e-01	-1.12e-01	7.50e-01
GO:0072659 protein localization to plasma membrane	75	9.27e-02	1.12e-01	4.07e-01
GO:0007612 learning	14	4.67e-01	-1.12e-01	7.92e-01
GO:0050852 T cell receptor signaling pathway	50	1.70e-01	1.12e-01	5.31e-01
GO:0006893 Golgi to plasma membrane transport	19	3.98e-01	-1.12e-01	7.56e-01
GO:0051536 iron-sulfur cluster binding	12	5.02e-01	1.12e-01	8.06e-01
GO:0050839 cell adhesion molecule binding	21	3.75e-01	-1.12e-01	7.45e-01
GO:0007265 Ras protein signal transduction	37	2.40e-01	-1.12e-01	6.20e-01
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation	14	4.70e-01	-1.12e-01	7.92e-01
GO:0030178 negative regulation of Wnt signaling pathway	17	4.26e-01	-1.12e-01	7.74e-01
GO:0043015 gamma-tubulin binding	21	3.77e-01	1.11e-01	7.45e-01
GO:0060326 cell chemotaxis	27	3.17e-01	-1.11e-01	6.95e-01
GO:0005938 cell cortex	74	9.85e-02	1.11e-01	4.19e-01
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	67	1.16e-01	1.11e-01	4.50e-01
GO:0004930 G protein-coupled receptor activity	58	1.45e-01	-1.11e-01	4.96e-01
GO:0005686 U2 snRNP	16	4.43e-01	-1.11e-01	7.82e-01
GO:0060079 excitatory postsynaptic potential	16	4.44e-01	1.10e-01	7.82e-01
GO:0051260 protein homooligomerization	47	1.92e-01	-1.10e-01	5.66e-01
GO:0051219 phosphoprotein binding	20	3.94e-01	1.10e-01	7.54e-01
GO:0008361 regulation of cell size	13	4.93e-01	1.10e-01	8.02e-01
GO:0017053 transcription repressor complex	34	2.68e-01	-1.10e-01	6.50e-01
GO:0035035 histone acetyltransferase binding	12	5.11e-01	-1.10e-01	8.13e-01
GO:0035591 signaling adaptor activity	40	2.32e-01	1.09e-01	6.09e-01
GO:0004252 serine-type endopeptidase activity	50	1.83e-01	1.09e-01	5.52e-01
GO:0007059 chromosome segregation	41	2.27e-01	1.09e-01	6.04e-01
GO:0043923 positive regulation by host of viral transcription	12	5.14e-01	1.09e-01	8.15e-01
GO:0032481 positive regulation of type I interferon production	18	4.24e-01	1.09e-01	7.73e-01
GO:0007605 sensory perception of sound	54	1.67e-01	1.09e-01	5.27e-01
GO:0061630 ubiquitin protein ligase activity	176	1.30e-02	-1.09e-01	1.70e-01
GO:0005776 autophagosome	41	2.29e-01	1.09e-01	6.04e-01
GO:0032880 regulation of protein localization	42	2.23e-01	1.09e-01	5.99e-01
GO:1900181 negative regulation of protein localization to nucleus	11	5.33e-01	-1.09e-01	8.27e-01
GO:0005509 calcium ion binding	261	2.62e-03	1.09e-01	7.60e-02
GO:0022008 neurogenesis	31	2.97e-01	-1.08e-01	6.79e-01
GO:0000159 protein phosphatase type 2A complex	12	5.16e-01	-1.08e-01	8.16e-01
GO:0001649 osteoblast differentiation	39	2.43e-01	-1.08e-01	6.22e-01
GO:0006099 tricarboxylic acid cycle	19	4.15e-01	1.08e-01	7.72e-01
GO:0045824 negative regulation of innate immune response	16	4.55e-01	-1.08e-01	7.86e-01
GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity	34	2.77e-01	1.08e-01	6.64e-01
GO:0034644 cellular response to UV	33	2.84e-01	-1.08e-01	6.64e-01
GO:0005158 insulin receptor binding	13	5.01e-01	-1.08e-01	8.06e-01
GO:0030220 platelet formation	11	5.37e-01	-1.07e-01	8.29e-01
GO:0072542 protein phosphatase activator activity	10	5.57e-01	-1.07e-01	8.40e-01
GO:0051560 mitochondrial calcium ion homeostasis	13	5.03e-01	-1.07e-01	8.06e-01
GO:0016460 myosin II complex	12	5.21e-01	-1.07e-01	8.22e-01
GO:0098839 postsynaptic density membrane	34	2.80e-01	1.07e-01	6.64e-01
GO:0042391 regulation of membrane potential	13	5.06e-01	-1.07e-01	8.08e-01
GO:0004843 cysteine-type deubiquitinase activity	58	1.61e-01	-1.06e-01	5.20e-01
GO:0005795 Golgi stack	18	4.35e-01	1.06e-01	7.79e-01
GO:0030218 erythrocyte differentiation	27	3.39e-01	1.06e-01	7.18e-01
GO:0008408 3’-5’ exonuclease activity	10	5.61e-01	-1.06e-01	8.42e-01
GO:0007032 endosome organization	28	3.32e-01	-1.06e-01	7.12e-01
GO:0045740 positive regulation of DNA replication	11	5.43e-01	-1.06e-01	8.34e-01
GO:0016922 nuclear receptor binding	21	4.01e-01	1.06e-01	7.60e-01
GO:0000939 inner kinetochore	10	5.64e-01	1.06e-01	8.42e-01
GO:0002376 immune system process	12	5.27e-01	1.05e-01	8.25e-01
GO:0051382 kinetochore assembly	11	5.46e-01	1.05e-01	8.35e-01
GO:0007517 muscle organ development	11	5.46e-01	1.05e-01	8.35e-01
GO:0030864 cortical actin cytoskeleton	32	3.04e-01	1.05e-01	6.84e-01
GO:0005765 lysosomal membrane	137	3.44e-02	1.05e-01	2.72e-01
GO:0030838 positive regulation of actin filament polymerization	26	3.55e-01	1.05e-01	7.30e-01
GO:0005929 cilium	78	1.11e-01	1.05e-01	4.37e-01
GO:0042127 regulation of cell population proliferation	44	2.30e-01	1.05e-01	6.06e-01
GO:0016239 positive regulation of macroautophagy	17	4.56e-01	1.04e-01	7.86e-01
GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	35	2.86e-01	-1.04e-01	6.65e-01
GO:0030295 protein kinase activator activity	21	4.08e-01	-1.04e-01	7.68e-01
GO:0006605 protein targeting	18	4.44e-01	1.04e-01	7.82e-01
GO:0050830 defense response to Gram-positive bacterium	15	4.85e-01	1.04e-01	8.02e-01
GO:0005096 GTPase activator activity	151	2.76e-02	1.04e-01	2.45e-01
GO:0005507 copper ion binding	24	3.78e-01	-1.04e-01	7.45e-01
GO:0005125 cytokine activity	28	3.42e-01	1.04e-01	7.19e-01
GO:0050890 cognition	18	4.49e-01	1.03e-01	7.84e-01
GO:0045190 isotype switching	13	5.22e-01	-1.03e-01	8.22e-01
GO:0032206 positive regulation of telomere maintenance	14	5.07e-01	-1.02e-01	8.08e-01
GO:0007417 central nervous system development	42	2.51e-01	1.02e-01	6.33e-01
GO:0000209 protein polyubiquitination	77	1.21e-01	-1.02e-01	4.55e-01
GO:0042826 histone deacetylase binding	66	1.51e-01	-1.02e-01	5.03e-01
GO:0034237 protein kinase A regulatory subunit binding	15	4.93e-01	-1.02e-01	8.02e-01
GO:0001569 branching involved in blood vessel morphogenesis	15	4.93e-01	-1.02e-01	8.02e-01
GO:0030424 axon	120	5.41e-02	-1.02e-01	3.26e-01
GO:0043005 neuron projection	97	8.31e-02	1.02e-01	3.88e-01
GO:0031398 positive regulation of protein ubiquitination	40	2.65e-01	1.02e-01	6.50e-01
GO:0006260 DNA replication	34	3.04e-01	-1.02e-01	6.84e-01
GO:0034504 protein localization to nucleus	20	4.31e-01	-1.02e-01	7.78e-01
GO:0003677 DNA binding	337	1.44e-03	-1.01e-01	5.34e-02
GO:0070847 core mediator complex	19	4.45e-01	1.01e-01	7.82e-01
GO:0042060 wound healing	28	3.54e-01	1.01e-01	7.30e-01
GO:0008092 cytoskeletal protein binding	15	4.98e-01	-1.01e-01	8.03e-01
GO:0000166 nucleotide binding	37	2.88e-01	-1.01e-01	6.68e-01
GO:0034497 protein localization to phagophore assembly site	11	5.63e-01	1.01e-01	8.42e-01
GO:0004864 protein phosphatase inhibitor activity	13	5.29e-01	-1.01e-01	8.26e-01
GO:0001947 heart looping	23	4.05e-01	1.00e-01	7.63e-01
GO:0090316 positive regulation of intracellular protein transport	14	5.17e-01	1.00e-01	8.16e-01
GO:0006865 amino acid transport	11	5.67e-01	9.98e-02	8.43e-01
GO:0004842 ubiquitin-protein transferase activity	65	1.65e-01	-9.98e-02	5.24e-01
GO:0000381 regulation of alternative mRNA splicing, via spliceosome	31	3.38e-01	-9.95e-02	7.17e-01
GO:0030141 secretory granule	18	4.66e-01	9.94e-02	7.92e-01
GO:0050905 neuromuscular process	10	5.87e-01	9.93e-02	8.57e-01
GO:0061136 regulation of proteasomal protein catabolic process	11	5.70e-01	9.89e-02	8.45e-01
GO:0042162 telomeric DNA binding	20	4.44e-01	-9.88e-02	7.82e-01
GO:0030534 adult behavior	10	5.89e-01	9.87e-02	8.58e-01
GO:0031491 nucleosome binding	25	3.94e-01	-9.86e-02	7.54e-01
GO:0030183 B cell differentiation	27	3.77e-01	9.83e-02	7.45e-01
GO:0008076 voltage-gated potassium channel complex	21	4.36e-01	-9.83e-02	7.80e-01
GO:0071526 semaphorin-plexin signaling pathway	23	4.19e-01	-9.74e-02	7.72e-01
GO:0045746 negative regulation of Notch signaling pathway	15	5.14e-01	9.72e-02	8.15e-01
GO:0061608 nuclear import signal receptor activity	14	5.29e-01	-9.72e-02	8.26e-01
GO:0042981 regulation of apoptotic process	54	2.18e-01	-9.69e-02	5.93e-01
GO:0031901 early endosome membrane	75	1.47e-01	9.69e-02	4.99e-01
GO:0045666 positive regulation of neuron differentiation	26	3.93e-01	9.68e-02	7.54e-01
GO:0045165 cell fate commitment	20	4.54e-01	9.68e-02	7.86e-01
GO:0031124 mRNA 3’-end processing	13	5.46e-01	9.67e-02	8.35e-01
GO:0001666 response to hypoxia	51	2.33e-01	-9.65e-02	6.10e-01
GO:0007094 mitotic spindle assembly checkpoint signaling	19	4.67e-01	9.65e-02	7.92e-01
GO:0006346 DNA methylation-dependent constitutive heterochromatin formation	10	5.98e-01	-9.64e-02	8.59e-01
GO:0043113 receptor clustering	12	5.64e-01	-9.62e-02	8.42e-01
GO:1902895 positive regulation of miRNA transcription	24	4.16e-01	-9.59e-02	7.72e-01
GO:0070374 positive regulation of ERK1 and ERK2 cascade	59	2.03e-01	9.59e-02	5.77e-01
GO:0140627 ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	10	6.00e-01	-9.59e-02	8.59e-01
GO:0060976 coronary vasculature development	18	4.82e-01	-9.58e-02	8.01e-01
GO:0008654 phospholipid biosynthetic process	12	5.67e-01	-9.54e-02	8.43e-01
GO:0051315 attachment of mitotic spindle microtubules to kinetochore	10	6.02e-01	9.52e-02	8.59e-01
GO:0051018 protein kinase A binding	12	5.71e-01	-9.44e-02	8.46e-01
GO:0140297 DNA-binding transcription factor binding	72	1.67e-01	-9.44e-02	5.27e-01
GO:0017025 TBP-class protein binding	18	4.88e-01	-9.44e-02	8.02e-01
GO:0045995 regulation of embryonic development	27	3.97e-01	-9.41e-02	7.56e-01
GO:0006644 phospholipid metabolic process	11	5.89e-01	9.40e-02	8.58e-01
GO:0000400 four-way junction DNA binding	14	5.43e-01	9.38e-02	8.34e-01
GO:1903078 positive regulation of protein localization to plasma membrane	21	4.57e-01	9.38e-02	7.86e-01
GO:0009887 animal organ morphogenesis	34	3.44e-01	-9.37e-02	7.22e-01
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process	19	4.82e-01	9.31e-02	8.01e-01
GO:0045022 early endosome to late endosome transport	19	4.83e-01	9.29e-02	8.01e-01
GO:0030276 clathrin binding	17	5.08e-01	9.28e-02	8.08e-01
GO:0051965 positive regulation of synapse assembly	22	4.51e-01	9.28e-02	7.85e-01
GO:0061436 establishment of skin barrier	13	5.63e-01	-9.27e-02	8.42e-01
GO:0035987 endodermal cell differentiation	22	4.56e-01	9.19e-02	7.86e-01
GO:0030168 platelet activation	11	5.98e-01	-9.18e-02	8.59e-01
GO:0003777 microtubule motor activity	23	4.47e-01	9.16e-02	7.83e-01
GO:0048870 cell motility	12	5.84e-01	9.14e-02	8.55e-01
GO:0035567 non-canonical Wnt signaling pathway	13	5.69e-01	9.13e-02	8.44e-01
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway	42	3.07e-01	9.11e-02	6.86e-01
GO:0036211 protein modification process	16	5.28e-01	9.10e-02	8.26e-01
GO:0003712 transcription coregulator activity	76	1.73e-01	-9.04e-02	5.36e-01
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific	113	9.73e-02	-9.04e-02	4.15e-01
GO:0090734 site of DNA damage	22	4.63e-01	-9.03e-02	7.92e-01
GO:0050728 negative regulation of inflammatory response	48	2.81e-01	8.99e-02	6.64e-01
GO:0016791 phosphatase activity	15	5.47e-01	-8.99e-02	8.35e-01
GO:0009898 cytoplasmic side of plasma membrane	49	2.78e-01	8.95e-02	6.64e-01
GO:0071222 cellular response to lipopolysaccharide	45	2.99e-01	8.95e-02	6.80e-01
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway	12	5.92e-01	8.94e-02	8.58e-01
GO:0006355 regulation of DNA-templated transcription	160	5.14e-02	-8.94e-02	3.19e-01
GO:0072686 mitotic spindle	69	2.00e-01	8.94e-02	5.77e-01
GO:0005813 centrosome	344	4.57e-03	8.94e-02	1.02e-01
GO:0106222 lncRNA binding	17	5.24e-01	-8.93e-02	8.23e-01
GO:0030500 regulation of bone mineralization	12	5.93e-01	8.92e-02	8.59e-01
GO:0050870 positive regulation of T cell activation	14	5.64e-01	8.91e-02	8.42e-01
GO:0003148 outflow tract septum morphogenesis	12	5.95e-01	-8.86e-02	8.59e-01
GO:0005604 basement membrane	44	3.10e-01	-8.86e-02	6.86e-01
GO:0060612 adipose tissue development	23	4.64e-01	8.83e-02	7.92e-01
GO:0008033 tRNA processing	15	5.54e-01	-8.83e-02	8.40e-01
GO:0032868 response to insulin	22	4.74e-01	-8.82e-02	7.95e-01
GO:0001516 prostaglandin biosynthetic process	10	6.29e-01	8.81e-02	8.79e-01
GO:0005802 trans-Golgi network	100	1.29e-01	8.81e-02	4.69e-01
GO:0071347 cellular response to interleukin-1	17	5.31e-01	8.79e-02	8.26e-01
GO:0030878 thyroid gland development	14	5.69e-01	8.79e-02	8.44e-01
GO:0061484 hematopoietic stem cell homeostasis	12	5.99e-01	-8.78e-02	8.59e-01
GO:0005903 brush border	20	4.97e-01	-8.78e-02	8.02e-01
GO:0019902 phosphatase binding	23	4.67e-01	8.77e-02	7.92e-01
GO:0050804 modulation of chemical synaptic transmission	34	3.77e-01	8.76e-02	7.45e-01
GO:0070840 dynein complex binding	11	6.16e-01	8.75e-02	8.68e-01
GO:0009925 basal plasma membrane	12	6.00e-01	8.75e-02	8.59e-01
GO:0043010 camera-type eye development	22	4.78e-01	8.74e-02	7.99e-01
GO:0070382 exocytic vesicle	10	6.33e-01	8.73e-02	8.81e-01
GO:0097546 ciliary base	17	5.34e-01	8.71e-02	8.27e-01
GO:0001817 regulation of cytokine production	26	4.43e-01	-8.70e-02	7.82e-01
GO:0061025 membrane fusion	21	4.91e-01	-8.69e-02	8.02e-01
GO:0031201 SNARE complex	33	3.88e-01	-8.69e-02	7.52e-01
GO:1990782 protein tyrosine kinase binding	14	5.74e-01	8.68e-02	8.46e-01
GO:0070530 K63-linked polyubiquitin modification-dependent protein binding	18	5.24e-01	-8.68e-02	8.23e-01
GO:0006303 double-strand break repair via nonhomologous end joining	20	5.02e-01	-8.67e-02	8.06e-01
GO:0005021 vascular endothelial growth factor receptor activity	15	5.61e-01	-8.67e-02	8.42e-01
GO:0060348 bone development	26	4.45e-01	8.66e-02	7.82e-01
GO:0009968 negative regulation of signal transduction	14	5.75e-01	8.66e-02	8.46e-01
GO:0005778 peroxisomal membrane	28	4.28e-01	-8.65e-02	7.75e-01
GO:0051539 4 iron, 4 sulfur cluster binding	33	3.90e-01	-8.65e-02	7.54e-01
GO:0005666 RNA polymerase III complex	12	6.04e-01	8.65e-02	8.59e-01
GO:0043627 response to estrogen	10	6.36e-01	-8.64e-02	8.84e-01
GO:0016604 nuclear body	174	5.00e-02	-8.63e-02	3.16e-01
GO:0045722 positive regulation of gluconeogenesis	11	6.21e-01	8.62e-02	8.74e-01
GO:0009986 cell surface	183	4.59e-02	8.57e-02	3.08e-01
GO:0051726 regulation of cell cycle	104	1.32e-01	-8.56e-02	4.74e-01
GO:0032587 ruffle membrane	41	3.47e-01	8.50e-02	7.25e-01
GO:0016459 myosin complex	24	4.71e-01	-8.50e-02	7.92e-01
GO:0016592 mediator complex	28	4.37e-01	-8.49e-02	7.80e-01
GO:0035082 axoneme assembly	10	6.43e-01	8.46e-02	8.88e-01
GO:0014069 postsynaptic density	96	1.53e-01	8.45e-02	5.05e-01
GO:0006006 glucose metabolic process	26	4.56e-01	-8.44e-02	7.86e-01
GO:0048511 rhythmic process	25	4.65e-01	-8.44e-02	7.92e-01
GO:2000114 regulation of establishment of cell polarity	10	6.46e-01	8.39e-02	8.90e-01
GO:0003180 aortic valve morphogenesis	11	6.31e-01	-8.38e-02	8.79e-01
GO:0003755 peptidyl-prolyl cis-trans isomerase activity	30	4.27e-01	-8.37e-02	7.75e-01
GO:0042813 Wnt receptor activity	12	6.16e-01	8.37e-02	8.68e-01
GO:0031507 heterochromatin formation	27	4.52e-01	-8.36e-02	7.85e-01
GO:0030215 semaphorin receptor binding	11	6.31e-01	-8.35e-02	8.80e-01
GO:0006366 transcription by RNA polymerase II	73	2.18e-01	-8.34e-02	5.93e-01
GO:0008104 protein localization	67	2.40e-01	8.31e-02	6.20e-01
GO:0005977 glycogen metabolic process	13	6.05e-01	8.30e-02	8.59e-01
GO:0022857 transmembrane transporter activity	41	3.59e-01	-8.29e-02	7.32e-01
GO:0050772 positive regulation of axonogenesis	13	6.05e-01	-8.29e-02	8.59e-01
GO:0071407 cellular response to organic cyclic compound	11	6.35e-01	-8.27e-02	8.83e-01
GO:0004177 aminopeptidase activity	13	6.06e-01	-8.26e-02	8.59e-01
GO:0045494 photoreceptor cell maintenance	24	4.84e-01	8.25e-02	8.02e-01
GO:0001784 phosphotyrosine residue binding	27	4.60e-01	-8.22e-02	7.89e-01
GO:0005739 mitochondrion	607	6.04e-04	8.21e-02	3.28e-02
GO:0000082 G1/S transition of mitotic cell cycle	40	3.70e-01	8.20e-02	7.41e-01
GO:0005689 U12-type spliceosomal complex	20	5.26e-01	-8.20e-02	8.24e-01
GO:0001657 ureteric bud development	14	5.97e-01	-8.16e-02	8.59e-01
GO:0006974 DNA damage response	120	1.24e-01	-8.14e-02	4.61e-01
GO:0061077 chaperone-mediated protein folding	16	5.75e-01	-8.11e-02	8.46e-01
GO:0051019 mitogen-activated protein kinase binding	11	6.43e-01	8.08e-02	8.88e-01
GO:0071339 MLL1 complex	18	5.54e-01	-8.06e-02	8.40e-01
GO:0045727 positive regulation of translation	36	4.04e-01	8.04e-02	7.62e-01
GO:0005794 Golgi apparatus	468	3.14e-03	8.01e-02	8.66e-02
GO:0006906 vesicle fusion	15	5.91e-01	8.01e-02	8.58e-01
GO:0030134 COPII-coated ER to Golgi transport vesicle	21	5.26e-01	7.99e-02	8.24e-01
GO:0005154 epidermal growth factor receptor binding	19	5.47e-01	-7.98e-02	8.35e-01
GO:0015035 protein-disulfide reductase activity	14	6.05e-01	7.98e-02	8.59e-01
GO:0008333 endosome to lysosome transport	32	4.36e-01	7.95e-02	7.80e-01
GO:0071805 potassium ion transmembrane transport	41	3.79e-01	7.94e-02	7.45e-01
GO:0016363 nuclear matrix	46	3.52e-01	-7.93e-02	7.29e-01
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding	84	2.10e-01	7.91e-02	5.85e-01
GO:0036297 interstrand cross-link repair	24	5.04e-01	7.89e-02	8.06e-01
GO:0048015 phosphatidylinositol-mediated signaling	18	5.63e-01	7.88e-02	8.42e-01
GO:0017134 fibroblast growth factor binding	12	6.36e-01	7.88e-02	8.84e-01
GO:0140672 ATAC complex	11	6.51e-01	-7.88e-02	8.94e-01
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway	19	5.55e-01	7.83e-02	8.40e-01
GO:0140801 histone H2AXY142 kinase activity	22	5.25e-01	-7.83e-02	8.24e-01
GO:1990166 protein localization to site of double-strand break	10	6.68e-01	7.83e-02	9.00e-01
GO:0007399 nervous system development	89	2.03e-01	-7.81e-02	5.77e-01
GO:0044291 cell-cell contact zone	13	6.27e-01	-7.79e-02	8.77e-01
GO:0005768 endosome	113	1.53e-01	7.78e-02	5.05e-01
GO:0002250 adaptive immune response	21	5.38e-01	7.76e-02	8.29e-01
GO:0001525 angiogenesis	85	2.17e-01	7.76e-02	5.92e-01
GO:0006493 protein O-linked glycosylation	31	4.56e-01	-7.73e-02	7.86e-01
GO:0051879 Hsp90 protein binding	26	4.95e-01	7.73e-02	8.02e-01
GO:0032731 positive regulation of interleukin-1 beta production	12	6.43e-01	7.73e-02	8.88e-01
GO:0035791 platelet-derived growth factor receptor-beta signaling pathway	15	6.05e-01	-7.72e-02	8.59e-01
GO:0001764 neuron migration	40	4.01e-01	-7.68e-02	7.59e-01
GO:0001222 transcription corepressor binding	27	4.90e-01	-7.67e-02	8.02e-01
GO:0045668 negative regulation of osteoblast differentiation	27	4.91e-01	7.66e-02	8.02e-01
GO:0030027 lamellipodium	92	2.08e-01	-7.61e-02	5.83e-01
GO:0007229 integrin-mediated signaling pathway	45	3.78e-01	-7.60e-02	7.45e-01
GO:0045814 negative regulation of gene expression, epigenetic	16	5.99e-01	-7.60e-02	8.59e-01
GO:0048167 regulation of synaptic plasticity	16	5.99e-01	-7.59e-02	8.59e-01
GO:1990837 sequence-specific double-stranded DNA binding	47	3.70e-01	7.56e-02	7.41e-01
GO:1900182 positive regulation of protein localization to nucleus	25	5.13e-01	-7.56e-02	8.15e-01
GO:0060041 retina development in camera-type eye	21	5.49e-01	-7.55e-02	8.37e-01
GO:0008542 visual learning	20	5.59e-01	7.54e-02	8.42e-01
GO:0097191 extrinsic apoptotic signaling pathway	20	5.60e-01	7.53e-02	8.42e-01
GO:0001570 vasculogenesis	26	5.07e-01	-7.51e-02	8.08e-01
GO:0035861 site of double-strand break	58	3.24e-01	-7.50e-02	6.99e-01
GO:0050919 negative chemotaxis	20	5.63e-01	7.48e-02	8.42e-01
GO:0070300 phosphatidic acid binding	13	6.41e-01	7.47e-02	8.88e-01
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity	19	5.73e-01	-7.46e-02	8.46e-01
GO:0045893 positive regulation of DNA-templated transcription	222	5.62e-02	-7.46e-02	3.28e-01
GO:0032922 circadian regulation of gene expression	34	4.52e-01	-7.45e-02	7.85e-01
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane	18	5.86e-01	7.42e-02	8.56e-01
GO:0030159 signaling receptor complex adaptor activity	13	6.44e-01	7.41e-02	8.88e-01
GO:0016180 snRNA processing	10	6.85e-01	-7.41e-02	9.03e-01
GO:0071949 FAD binding	27	5.06e-01	7.40e-02	8.08e-01
GO:0019838 growth factor binding	11	6.71e-01	-7.40e-02	9.00e-01
GO:0001756 somitogenesis	25	5.24e-01	-7.36e-02	8.23e-01
GO:0006909 phagocytosis	22	5.50e-01	7.36e-02	8.37e-01
GO:0035401 histone H3Y41 kinase activity	21	5.61e-01	-7.33e-02	8.42e-01
GO:0006915 apoptotic process	135	1.43e-01	7.31e-02	4.94e-01
GO:0060412 ventricular septum morphogenesis	18	5.93e-01	7.27e-02	8.59e-01
GO:0010629 negative regulation of gene expression	101	2.08e-01	7.26e-02	5.83e-01
GO:0098794 postsynapse	66	3.08e-01	7.26e-02	6.86e-01
GO:0015701 bicarbonate transport	11	6.77e-01	-7.25e-02	9.00e-01
GO:0002020 protease binding	44	4.07e-01	7.24e-02	7.65e-01
GO:0000976 transcription cis-regulatory region binding	54	3.58e-01	-7.23e-02	7.32e-01
GO:0030425 dendrite	133	1.51e-01	-7.22e-02	5.03e-01
GO:0072657 protein localization to membrane	19	5.86e-01	-7.22e-02	8.56e-01
GO:0035264 multicellular organism growth	67	3.08e-01	-7.20e-02	6.86e-01
GO:0002931 response to ischemia	10	6.95e-01	-7.16e-02	9.11e-01
GO:0008154 actin polymerization or depolymerization	12	6.68e-01	-7.16e-02	9.00e-01
GO:0007368 determination of left/right symmetry	28	5.13e-01	7.14e-02	8.15e-01
GO:0034063 stress granule assembly	21	5.72e-01	-7.13e-02	8.46e-01
GO:0072344 rescue of stalled ribosome	26	5.30e-01	-7.12e-02	8.26e-01
GO:0051123 RNA polymerase II preinitiation complex assembly	16	6.22e-01	-7.12e-02	8.74e-01
GO:0030374 nuclear receptor coactivator activity	30	5.00e-01	-7.11e-02	8.05e-01
GO:0045747 positive regulation of Notch signaling pathway	23	5.56e-01	7.10e-02	8.40e-01
GO:0005576 extracellular region	239	5.96e-02	7.09e-02	3.35e-01
GO:0005783 endoplasmic reticulum	433	1.19e-02	7.08e-02	1.63e-01
GO:0034605 cellular response to heat	16	6.24e-01	-7.07e-02	8.76e-01
GO:2000045 regulation of G1/S transition of mitotic cell cycle	19	5.94e-01	7.07e-02	8.59e-01
GO:0030672 synaptic vesicle membrane	44	4.18e-01	7.06e-02	7.72e-01
GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity	10	7.00e-01	7.04e-02	9.11e-01
GO:0035019 somatic stem cell population maintenance	31	4.98e-01	7.03e-02	8.03e-01
GO:0007268 chemical synaptic transmission	33	4.87e-01	6.99e-02	8.02e-01
GO:0007409 axonogenesis	41	4.41e-01	-6.96e-02	7.82e-01
GO:0004711 ribosomal protein S6 kinase activity	32	4.96e-01	6.95e-02	8.02e-01
GO:0006869 lipid transport	27	5.32e-01	6.95e-02	8.27e-01
GO:0035331 negative regulation of hippo signaling	18	6.10e-01	-6.94e-02	8.64e-01
GO:0006874 intracellular calcium ion homeostasis	37	4.69e-01	-6.88e-02	7.92e-01
GO:0050660 flavin adenine dinucleotide binding	33	4.96e-01	6.85e-02	8.02e-01
GO:0051028 mRNA transport	27	5.38e-01	-6.84e-02	8.29e-01
GO:0060236 regulation of mitotic spindle organization	12	6.82e-01	-6.84e-02	9.02e-01
GO:0048786 presynaptic active zone	10	7.09e-01	6.81e-02	9.14e-01
GO:0017022 myosin binding	11	6.96e-01	-6.81e-02	9.11e-01
GO:0042383 sarcolemma	37	4.75e-01	6.79e-02	7.96e-01
GO:0005925 focal adhesion	115	2.10e-01	-6.78e-02	5.84e-01
GO:0048487 beta-tubulin binding	22	5.83e-01	6.76e-02	8.55e-01
GO:0007626 locomotory behavior	28	5.36e-01	6.75e-02	8.29e-01
GO:0030282 bone mineralization	24	5.67e-01	6.75e-02	8.43e-01
GO:0060090 molecular adaptor activity	75	3.14e-01	6.74e-02	6.90e-01
GO:0098655 monoatomic cation transmembrane transport	14	6.65e-01	6.70e-02	8.99e-01
GO:0032211 negative regulation of telomere maintenance via telomerase	10	7.14e-01	-6.69e-02	9.16e-01
GO:0030073 insulin secretion	13	6.77e-01	-6.68e-02	9.00e-01
GO:0043130 ubiquitin binding	62	3.64e-01	-6.67e-02	7.37e-01
GO:0001726 ruffle	43	4.51e-01	6.64e-02	7.85e-01
GO:0051894 positive regulation of focal adhesion assembly	15	6.56e-01	6.64e-02	8.96e-01
GO:1990023 mitotic spindle midzone	10	7.16e-01	6.63e-02	9.17e-01
GO:0098586 cellular response to virus	22	5.90e-01	-6.63e-02	8.58e-01
GO:0005516 calmodulin binding	68	3.45e-01	6.63e-02	7.22e-01
GO:0035091 phosphatidylinositol binding	74	3.25e-01	6.63e-02	7.00e-01
GO:0000139 Golgi membrane	262	6.65e-02	6.60e-02	3.47e-01
GO:0019903 protein phosphatase binding	49	4.24e-01	6.60e-02	7.73e-01
GO:0048705 skeletal system morphogenesis	14	6.69e-01	6.59e-02	9.00e-01
GO:0045892 negative regulation of DNA-templated transcription	174	1.35e-01	-6.58e-02	4.80e-01
GO:0009617 response to bacterium	36	4.96e-01	-6.55e-02	8.02e-01
GO:0071168 protein localization to chromatin	17	6.40e-01	6.55e-02	8.88e-01
GO:0007029 endoplasmic reticulum organization	16	6.50e-01	6.54e-02	8.94e-01
GO:0031012 extracellular matrix	90	2.84e-01	-6.54e-02	6.64e-01
GO:0016235 aggresome	17	6.41e-01	6.54e-02	8.88e-01
GO:0070064 proline-rich region binding	10	7.20e-01	6.54e-02	9.18e-01
GO:0007080 mitotic metaphase chromosome alignment	23	5.87e-01	6.54e-02	8.57e-01
GO:0005667 transcription regulator complex	90	2.85e-01	-6.53e-02	6.64e-01
GO:0006396 RNA processing	21	6.05e-01	-6.52e-02	8.59e-01
GO:0048873 homeostasis of number of cells within a tissue	14	6.73e-01	6.52e-02	9.00e-01
GO:0051865 protein autoubiquitination	38	4.88e-01	-6.51e-02	8.02e-01
GO:0071356 cellular response to tumor necrosis factor	37	4.95e-01	-6.49e-02	8.02e-01
GO:0032735 positive regulation of interleukin-12 production	12	6.98e-01	6.48e-02	9.11e-01
GO:0051403 stress-activated MAPK cascade	12	6.98e-01	6.47e-02	9.11e-01
GO:0043021 ribonucleoprotein complex binding	23	5.92e-01	6.46e-02	8.58e-01
GO:0000176 nuclear exosome (RNase complex)	12	6.99e-01	-6.45e-02	9.11e-01
GO:0055088 lipid homeostasis	19	6.27e-01	-6.44e-02	8.77e-01
GO:1901673 regulation of mitotic spindle assembly	16	6.56e-01	-6.43e-02	8.96e-01
GO:0031966 mitochondrial membrane	38	4.94e-01	6.42e-02	8.02e-01
GO:0051649 establishment of localization in cell	40	4.83e-01	6.42e-02	8.01e-01
GO:0005886 plasma membrane	1527	4.12e-05	6.41e-02	5.21e-03
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	11	7.14e-01	6.38e-02	9.16e-01
GO:0000287 magnesium ion binding	150	1.80e-01	6.35e-02	5.49e-01
GO:0042742 defense response to bacterium	28	5.62e-01	6.34e-02	8.42e-01
GO:0010008 endosome membrane	86	3.11e-01	6.33e-02	6.87e-01
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II	12	7.05e-01	-6.31e-02	9.14e-01
GO:0001654 eye development	17	6.53e-01	6.30e-02	8.95e-01
GO:0031547 brain-derived neurotrophic factor receptor signaling pathway	14	6.83e-01	-6.30e-02	9.03e-01
GO:0043014 alpha-tubulin binding	23	6.02e-01	6.28e-02	8.59e-01
GO:0050673 epithelial cell proliferation	20	6.27e-01	-6.27e-02	8.77e-01
GO:0034614 cellular response to reactive oxygen species	16	6.64e-01	-6.27e-02	8.99e-01
GO:0051259 protein complex oligomerization	14	6.86e-01	-6.25e-02	9.03e-01
GO:0031032 actomyosin structure organization	17	6.56e-01	-6.25e-02	8.96e-01
GO:0003281 ventricular septum development	15	6.76e-01	-6.24e-02	9.00e-01
GO:0099560 synaptic membrane adhesion	15	6.77e-01	-6.21e-02	9.00e-01
GO:0006400 tRNA modification	11	7.23e-01	6.18e-02	9.18e-01
GO:0005518 collagen binding	34	5.34e-01	-6.16e-02	8.27e-01
GO:0051302 regulation of cell division	11	7.24e-01	-6.16e-02	9.18e-01
GO:0070098 chemokine-mediated signaling pathway	10	7.36e-01	-6.15e-02	9.20e-01
GO:0003924 GTPase activity	176	1.60e-01	6.15e-02	5.20e-01
GO:0006506 GPI anchor biosynthetic process	25	5.96e-01	6.12e-02	8.59e-01
GO:0030175 filopodium	31	5.56e-01	6.11e-02	8.40e-01
GO:0010842 retina layer formation	12	7.14e-01	-6.10e-02	9.16e-01
GO:0070402 NADPH binding	10	7.38e-01	6.10e-02	9.20e-01
GO:1902600 proton transmembrane transport	59	4.19e-01	6.09e-02	7.72e-01
GO:0004198 calcium-dependent cysteine-type endopeptidase activity	10	7.39e-01	6.08e-02	9.20e-01
GO:0007155 cell adhesion	107	2.79e-01	-6.07e-02	6.64e-01
GO:0051087 protein-folding chaperone binding	55	4.38e-01	-6.05e-02	7.80e-01
GO:0031397 negative regulation of protein ubiquitination	33	5.48e-01	6.05e-02	8.35e-01
GO:0004713 protein tyrosine kinase activity	34	5.42e-01	-6.05e-02	8.34e-01
GO:0043410 positive regulation of MAPK cascade	61	4.14e-01	6.05e-02	7.72e-01
GO:0001664 G protein-coupled receptor binding	22	6.24e-01	6.04e-02	8.76e-01
GO:0003684 damaged DNA binding	34	5.43e-01	-6.03e-02	8.34e-01
GO:0051016 barbed-end actin filament capping	16	6.77e-01	-6.02e-02	9.00e-01
GO:0099523 presynaptic cytosol	11	7.30e-01	6.02e-02	9.20e-01
GO:0019882 antigen processing and presentation	11	7.32e-01	5.96e-02	9.20e-01
GO:0036503 ERAD pathway	59	4.30e-01	-5.95e-02	7.77e-01
GO:0034067 protein localization to Golgi apparatus	13	7.11e-01	-5.93e-02	9.16e-01
GO:0005741 mitochondrial outer membrane	95	3.20e-01	-5.91e-02	6.99e-01
GO:0007274 neuromuscular synaptic transmission	12	7.23e-01	-5.90e-02	9.18e-01
GO:0007281 germ cell development	14	7.02e-01	-5.90e-02	9.12e-01
GO:0061744 motor behavior	16	6.84e-01	5.88e-02	9.03e-01
GO:0006508 proteolysis	174	1.83e-01	5.87e-02	5.52e-01
GO:0046872 metal ion binding	877	3.56e-03	-5.86e-02	9.10e-02
GO:0030971 receptor tyrosine kinase binding	32	5.66e-01	5.86e-02	8.43e-01
GO:0045505 dynein intermediate chain binding	17	6.77e-01	-5.84e-02	9.00e-01
GO:0005789 endoplasmic reticulum membrane	402	4.61e-02	5.82e-02	3.08e-01
GO:0004676 3-phosphoinositide-dependent protein kinase activity	31	5.75e-01	5.82e-02	8.46e-01
GO:0007165 signal transduction	263	1.05e-01	5.82e-02	4.30e-01
GO:0007596 blood coagulation	25	6.15e-01	5.81e-02	8.68e-01
GO:0000049 tRNA binding	52	4.70e-01	-5.79e-02	7.92e-01
GO:0007040 lysosome organization	33	5.65e-01	-5.78e-02	8.43e-01
GO:0017148 negative regulation of translation	43	5.14e-01	-5.75e-02	8.15e-01
GO:0007005 mitochondrion organization	61	4.38e-01	5.74e-02	7.80e-01
GO:0030216 keratinocyte differentiation	27	6.06e-01	5.74e-02	8.59e-01
GO:0035403 histone H3T6 kinase activity	32	5.74e-01	5.74e-02	8.46e-01
GO:0006730 one-carbon metabolic process	13	7.20e-01	-5.74e-02	9.18e-01
GO:0000226 microtubule cytoskeleton organization	69	4.11e-01	5.73e-02	7.69e-01
GO:0000502 proteasome complex	13	7.21e-01	-5.72e-02	9.18e-01
GO:1901981 phosphatidylinositol phosphate binding	15	7.02e-01	5.71e-02	9.12e-01
GO:0051959 dynein light intermediate chain binding	16	6.93e-01	-5.70e-02	9.10e-01
GO:0000932 P-body	60	4.47e-01	-5.68e-02	7.83e-01
GO:0070888 E-box binding	21	6.53e-01	5.68e-02	8.95e-01
GO:0010595 positive regulation of endothelial cell migration	26	6.17e-01	5.66e-02	8.70e-01
GO:0005178 integrin binding	66	4.28e-01	-5.65e-02	7.75e-01
GO:0007267 cell-cell signaling	13	7.24e-01	-5.65e-02	9.18e-01
GO:0031941 filamentous actin	19	6.70e-01	-5.64e-02	9.00e-01
GO:0016324 apical plasma membrane	122	2.82e-01	5.64e-02	6.64e-01
GO:0000122 negative regulation of transcription by RNA polymerase II	395	5.57e-02	-5.64e-02	3.28e-01
GO:0051020 GTPase binding	15	7.06e-01	-5.63e-02	9.14e-01
GO:0009306 protein secretion	20	6.63e-01	5.62e-02	8.99e-01
GO:0005874 microtubule	131	2.68e-01	5.62e-02	6.50e-01
GO:0003341 cilium movement	10	7.59e-01	5.61e-02	9.20e-01
GO:0046330 positive regulation of JNK cascade	38	5.50e-01	-5.60e-02	8.37e-01
GO:0048839 inner ear development	12	7.37e-01	5.60e-02	9.20e-01
GO:0004867 serine-type endopeptidase inhibitor activity	21	6.57e-01	5.60e-02	8.97e-01
GO:0042147 retrograde transport, endosome to Golgi	50	4.95e-01	5.59e-02	8.02e-01
GO:0038066 p38MAPK cascade	12	7.38e-01	5.58e-02	9.20e-01
GO:0031902 late endosome membrane	67	4.33e-01	5.55e-02	7.78e-01
GO:0043539 protein serine/threonine kinase activator activity	34	5.76e-01	5.54e-02	8.47e-01
GO:0004497 monooxygenase activity	11	7.50e-01	5.54e-02	9.20e-01
GO:0008285 negative regulation of cell population proliferation	117	3.03e-01	5.52e-02	6.84e-01
GO:0006289 nucleotide-excision repair	22	6.55e-01	-5.51e-02	8.96e-01
GO:0035904 aorta development	15	7.13e-01	5.50e-02	9.16e-01
GO:0090201 negative regulation of release of cytochrome c from mitochondria	11	7.52e-01	-5.49e-02	9.20e-01
GO:0010314 phosphatidylinositol-5-phosphate binding	11	7.53e-01	-5.48e-02	9.20e-01
GO:0008217 regulation of blood pressure	20	6.74e-01	5.44e-02	9.00e-01
GO:0004714 transmembrane receptor protein tyrosine kinase activity	14	7.25e-01	5.44e-02	9.18e-01
GO:0019955 cytokine binding	11	7.56e-01	-5.40e-02	9.20e-01
GO:0050714 positive regulation of protein secretion	19	6.84e-01	5.40e-02	9.03e-01
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading	24	6.47e-01	-5.40e-02	8.90e-01
GO:0030334 regulation of cell migration	35	5.81e-01	5.39e-02	8.53e-01
GO:0006882 intracellular zinc ion homeostasis	13	7.40e-01	5.32e-02	9.20e-01
GO:0007369 gastrulation	10	7.72e-01	-5.29e-02	9.25e-01
GO:0001736 establishment of planar polarity	12	7.52e-01	5.27e-02	9.20e-01
GO:0000993 RNA polymerase II complex binding	23	6.63e-01	-5.26e-02	8.99e-01
GO:0051117 ATPase binding	44	5.47e-01	5.26e-02	8.35e-01
GO:0015031 protein transport	173	2.35e-01	5.25e-02	6.13e-01
GO:0030177 positive regulation of Wnt signaling pathway	17	7.08e-01	5.25e-02	9.14e-01
GO:0002062 chondrocyte differentiation	22	6.70e-01	5.25e-02	9.00e-01
GO:0000791 euchromatin	29	6.25e-01	-5.24e-02	8.76e-01
GO:0045111 intermediate filament cytoskeleton	23	6.64e-01	5.23e-02	8.99e-01
GO:2000786 positive regulation of autophagosome assembly	14	7.35e-01	5.23e-02	9.20e-01
GO:0005856 cytoskeleton	174	2.37e-01	5.21e-02	6.15e-01
GO:0007507 heart development	80	4.23e-01	-5.18e-02	7.73e-01
GO:0042472 inner ear morphogenesis	27	6.41e-01	5.18e-02	8.88e-01
GO:0000242 pericentriolar material	14	7.37e-01	-5.18e-02	9.20e-01
GO:0048471 perinuclear region of cytoplasm	289	1.32e-01	5.17e-02	4.74e-01
GO:0042177 negative regulation of protein catabolic process	24	6.61e-01	5.17e-02	8.99e-01
GO:0060173 limb development	24	6.62e-01	-5.16e-02	8.99e-01
GO:0035024 negative regulation of Rho protein signal transduction	14	7.39e-01	5.15e-02	9.20e-01
GO:0007179 transforming growth factor beta receptor signaling pathway	49	5.33e-01	-5.15e-02	8.27e-01
GO:0006955 immune response	42	5.64e-01	-5.14e-02	8.42e-01
GO:1990247 N6-methyladenosine-containing RNA reader activity	10	7.79e-01	-5.13e-02	9.25e-01
GO:0005004 GPI-linked ephrin receptor activity	12	7.59e-01	-5.11e-02	9.20e-01
GO:0005011 macrophage colony-stimulating factor receptor activity	12	7.59e-01	-5.11e-02	9.20e-01
GO:0005018 platelet-derived growth factor alpha-receptor activity	12	7.59e-01	-5.11e-02	9.20e-01
GO:0005020 stem cell factor receptor activity	12	7.59e-01	-5.11e-02	9.20e-01
GO:0008288 boss receptor activity	12	7.59e-01	-5.11e-02	9.20e-01
GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway	12	7.59e-01	-5.11e-02	9.20e-01
GO:0036323 vascular endothelial growth factor receptor-1 signaling pathway	12	7.59e-01	-5.11e-02	9.20e-01
GO:0036332 placental growth factor receptor activity	12	7.59e-01	-5.11e-02	9.20e-01
GO:0038145 macrophage colony-stimulating factor signaling pathway	12	7.59e-01	-5.11e-02	9.20e-01
GO:0060175 brain-derived neurotrophic factor receptor activity	12	7.59e-01	-5.11e-02	9.20e-01
GO:0016342 catenin complex	13	7.50e-01	5.11e-02	9.20e-01
GO:0003700 DNA-binding transcription factor activity	78	4.38e-01	-5.09e-02	7.80e-01
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway	41	5.74e-01	5.08e-02	8.46e-01
GO:0006954 inflammatory response	82	4.28e-01	5.07e-02	7.75e-01
GO:0070273 phosphatidylinositol-4-phosphate binding	17	7.18e-01	-5.06e-02	9.17e-01
GO:0045087 innate immune response	80	4.41e-01	4.99e-02	7.82e-01
GO:0043123 positive regulation of canonical NF-kappaB signal transduction	76	4.54e-01	4.97e-02	7.86e-01
GO:0046982 protein heterodimerization activity	130	3.28e-01	4.97e-02	7.07e-01
GO:0000776 kinetochore	90	4.18e-01	4.95e-02	7.72e-01
GO:0045453 bone resorption	11	7.77e-01	-4.94e-02	9.25e-01
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity	16	7.33e-01	-4.92e-02	9.20e-01
GO:0003779 actin binding	140	3.16e-01	-4.91e-02	6.94e-01
GO:0044325 transmembrane transporter binding	57	5.21e-01	4.91e-02	8.22e-01
GO:0052689 carboxylic ester hydrolase activity	12	7.69e-01	4.90e-02	9.24e-01
GO:0008306 associative learning	11	7.79e-01	4.89e-02	9.25e-01
GO:0016020 membrane	953	1.18e-02	4.87e-02	1.63e-01
GO:0038023 signaling receptor activity	39	5.99e-01	4.86e-02	8.59e-01
GO:0030206 chondroitin sulfate biosynthetic process	11	7.81e-01	4.85e-02	9.26e-01
GO:0016779 nucleotidyltransferase activity	11	7.81e-01	4.84e-02	9.26e-01
GO:0016358 dendrite development	19	7.16e-01	4.82e-02	9.17e-01
GO:0030336 negative regulation of cell migration	50	5.56e-01	-4.81e-02	8.40e-01
GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	76	4.70e-01	4.80e-02	7.92e-01
GO:0010634 positive regulation of epithelial cell migration	19	7.18e-01	4.79e-02	9.17e-01
GO:0046983 protein dimerization activity	70	4.89e-01	-4.79e-02	8.02e-01
GO:0035098 ESC/E(Z) complex	12	7.74e-01	4.78e-02	9.25e-01
GO:0050680 negative regulation of epithelial cell proliferation	25	6.80e-01	-4.77e-02	9.02e-01
GO:0030901 midbrain development	11	7.85e-01	4.76e-02	9.27e-01
GO:0031647 regulation of protein stability	57	5.35e-01	4.75e-02	8.28e-01
GO:0030514 negative regulation of BMP signaling pathway	27	6.70e-01	4.74e-02	9.00e-01
GO:0042803 protein homodimerization activity	372	1.19e-01	4.72e-02	4.55e-01
GO:0001676 long-chain fatty acid metabolic process	11	7.86e-01	-4.72e-02	9.28e-01
GO:0030330 DNA damage response, signal transduction by p53 class mediator	12	7.78e-01	4.71e-02	9.25e-01
GO:0097602 cullin family protein binding	16	7.45e-01	-4.70e-02	9.20e-01
GO:0009060 aerobic respiration	10	7.97e-01	-4.70e-02	9.34e-01
GO:0036126 sperm flagellum	32	6.46e-01	4.69e-02	8.90e-01
GO:0007275 multicellular organism development	26	6.80e-01	4.67e-02	9.02e-01
GO:0050766 positive regulation of phagocytosis	14	7.63e-01	-4.66e-02	9.20e-01
GO:0032580 Golgi cisterna membrane	27	6.76e-01	4.65e-02	9.00e-01
GO:0033617 mitochondrial cytochrome c oxidase assembly	13	7.72e-01	-4.65e-02	9.25e-01
GO:0010628 positive regulation of gene expression	146	3.35e-01	4.63e-02	7.13e-01
GO:0045214 sarcomere organization	12	7.82e-01	4.61e-02	9.26e-01
GO:0005102 signaling receptor binding	80	4.78e-01	4.59e-02	7.99e-01
GO:0006486 protein glycosylation	45	5.95e-01	-4.58e-02	8.59e-01
GO:0009611 response to wounding	20	7.23e-01	4.57e-02	9.18e-01
GO:0007204 positive regulation of cytosolic calcium ion concentration	19	7.31e-01	-4.56e-02	9.20e-01
GO:0097009 energy homeostasis	22	7.12e-01	-4.55e-02	9.16e-01
GO:0030182 neuron differentiation	57	5.53e-01	-4.55e-02	8.40e-01
GO:0048536 spleen development	23	7.06e-01	-4.54e-02	9.14e-01
GO:0006402 mRNA catabolic process	14	7.69e-01	4.53e-02	9.24e-01
GO:0003887 DNA-directed DNA polymerase activity	16	7.54e-01	-4.52e-02	9.20e-01
GO:0001671 ATPase activator activity	18	7.40e-01	-4.52e-02	9.20e-01
GO:0048255 mRNA stabilization	16	7.55e-01	-4.51e-02	9.20e-01
GO:0033077 T cell differentiation in thymus	18	7.40e-01	4.51e-02	9.20e-01
GO:0097190 apoptotic signaling pathway	20	7.27e-01	4.51e-02	9.19e-01
GO:0031625 ubiquitin protein ligase binding	172	3.09e-01	-4.51e-02	6.86e-01
GO:0005978 glycogen biosynthetic process	11	7.97e-01	4.49e-02	9.34e-01
GO:2001222 regulation of neuron migration	10	8.06e-01	4.49e-02	9.37e-01
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding	83	4.80e-01	-4.49e-02	8.00e-01
GO:0005635 nuclear envelope	77	4.97e-01	-4.49e-02	8.02e-01
GO:1990756 ubiquitin-like ligase-substrate adaptor activity	71	5.16e-01	-4.46e-02	8.16e-01
GO:0016601 Rac protein signal transduction	17	7.50e-01	4.46e-02	9.20e-01
GO:0048146 positive regulation of fibroblast proliferation	19	7.37e-01	4.45e-02	9.20e-01
GO:0031648 protein destabilization	32	6.66e-01	4.42e-02	9.00e-01
GO:0048477 oogenesis	14	7.75e-01	-4.42e-02	9.25e-01
GO:0032024 positive regulation of insulin secretion	21	7.27e-01	4.41e-02	9.19e-01
GO:0004725 protein tyrosine phosphatase activity	44	6.14e-01	-4.40e-02	8.68e-01
GO:0043231 intracellular membrane-bounded organelle	116	4.16e-01	4.38e-02	7.72e-01
GO:0120020 cholesterol transfer activity	11	8.02e-01	-4.37e-02	9.35e-01
GO:0001669 acrosomal vesicle	26	7.00e-01	4.37e-02	9.11e-01
GO:0007264 small GTPase-mediated signal transduction	47	6.07e-01	-4.34e-02	8.60e-01
GO:0072518 Rho-dependent protein serine/threonine kinase activity	32	6.72e-01	4.33e-02	9.00e-01
GO:0006357 regulation of transcription by RNA polymerase II	549	8.53e-02	-4.32e-02	3.88e-01
GO:0050699 WW domain binding	11	8.04e-01	-4.31e-02	9.36e-01
GO:0005654 nucleoplasm	1532	5.83e-03	-4.30e-02	1.18e-01
GO:0061462 protein localization to lysosome	10	8.14e-01	4.30e-02	9.38e-01
GO:0006513 protein monoubiquitination	27	7.00e-01	-4.28e-02	9.11e-01
GO:0048666 neuron development	26	7.06e-01	-4.28e-02	9.14e-01
GO:0031965 nuclear membrane	121	4.17e-01	-4.28e-02	7.72e-01
GO:0060325 face morphogenesis	21	7.34e-01	4.28e-02	9.20e-01
GO:0007613 memory	28	6.95e-01	-4.28e-02	9.11e-01
GO:0030544 Hsp70 protein binding	29	6.91e-01	-4.27e-02	9.08e-01
GO:0005758 mitochondrial intermembrane space	47	6.13e-01	4.26e-02	8.67e-01
GO:0050853 B cell receptor signaling pathway	19	7.48e-01	-4.25e-02	9.20e-01
GO:0007420 brain development	77	5.22e-01	-4.22e-02	8.23e-01
GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	12	8.00e-01	-4.22e-02	9.35e-01
GO:0016525 negative regulation of angiogenesis	35	6.67e-01	-4.21e-02	9.00e-01
GO:0001658 branching involved in ureteric bud morphogenesis	18	7.59e-01	-4.17e-02	9.20e-01
GO:0006631 fatty acid metabolic process	34	6.75e-01	4.16e-02	9.00e-01
GO:0140359 ABC-type transporter activity	11	8.13e-01	-4.13e-02	9.38e-01
GO:0042605 peptide antigen binding	10	8.22e-01	-4.10e-02	9.42e-01
GO:0008284 positive regulation of cell population proliferation	157	3.77e-01	4.09e-02	7.45e-01
GO:0030674 protein-macromolecule adaptor activity	73	5.51e-01	4.04e-02	8.38e-01
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding	12	8.09e-01	-4.02e-02	9.38e-01
GO:0030139 endocytic vesicle	37	6.73e-01	-4.02e-02	9.00e-01
GO:0070534 protein K63-linked ubiquitination	31	7.00e-01	-4.00e-02	9.11e-01
GO:0004519 endonuclease activity	14	7.96e-01	4.00e-02	9.34e-01
GO:0051059 NF-kappaB binding	22	7.47e-01	3.98e-02	9.20e-01
GO:0005682 U5 snRNP	10	8.28e-01	-3.97e-02	9.44e-01
GO:0000712 resolution of meiotic recombination intermediates	14	7.97e-01	3.97e-02	9.34e-01
GO:0006351 DNA-templated transcription	36	6.81e-01	-3.96e-02	9.02e-01
GO:0030307 positive regulation of cell growth	36	6.85e-01	-3.91e-02	9.03e-01
GO:0051787 misfolded protein binding	12	8.15e-01	-3.91e-02	9.38e-01
GO:0032869 cellular response to insulin stimulus	33	6.99e-01	3.89e-02	9.11e-01
GO:0120163 negative regulation of cold-induced thermogenesis	21	7.59e-01	-3.87e-02	9.20e-01
GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction	21	7.60e-01	-3.85e-02	9.20e-01
GO:0030246 carbohydrate binding	40	6.75e-01	-3.83e-02	9.00e-01
GO:0034113 heterotypic cell-cell adhesion	12	8.19e-01	3.81e-02	9.41e-01
GO:0016477 cell migration	136	4.49e-01	3.77e-02	7.84e-01
GO:0032543 mitochondrial translation	22	7.60e-01	3.77e-02	9.20e-01
GO:0030970 retrograde protein transport, ER to cytosol	12	8.22e-01	3.76e-02	9.42e-01
GO:0031418 L-ascorbic acid binding	14	8.09e-01	-3.74e-02	9.38e-01
GO:0071233 cellular response to L-leucine	10	8.39e-01	3.71e-02	9.44e-01
GO:0007010 cytoskeleton organization	51	6.47e-01	-3.70e-02	8.90e-01
GO:0012505 endomembrane system	97	5.30e-01	3.69e-02	8.26e-01
GO:0031122 cytoplasmic microtubule organization	28	7.37e-01	-3.67e-02	9.20e-01
GO:0048787 presynaptic active zone membrane	10	8.41e-01	3.66e-02	9.44e-01
GO:0060070 canonical Wnt signaling pathway	58	6.31e-01	3.65e-02	8.79e-01
GO:0007160 cell-matrix adhesion	41	6.86e-01	-3.65e-02	9.03e-01
GO:0003824 catalytic activity	10	8.42e-01	3.65e-02	9.44e-01
GO:0070588 calcium ion transmembrane transport	45	6.73e-01	3.64e-02	9.00e-01
GO:0090090 negative regulation of canonical Wnt signaling pathway	71	5.97e-01	-3.63e-02	8.59e-01
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle	23	7.64e-01	-3.62e-02	9.20e-01
GO:0000387 spliceosomal snRNP assembly	17	7.97e-01	3.60e-02	9.34e-01
GO:0140664 ATP-dependent DNA damage sensor activity	14	8.16e-01	3.59e-02	9.39e-01
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process	156	4.41e-01	-3.58e-02	7.82e-01
GO:0051216 cartilage development	21	7.77e-01	3.58e-02	9.25e-01
GO:0098978 glutamatergic synapse	231	3.51e-01	3.57e-02	7.29e-01
GO:0001662 behavioral fear response	12	8.31e-01	3.55e-02	9.44e-01
GO:0005884 actin filament	43	6.87e-01	3.55e-02	9.04e-01
GO:0001578 microtubule bundle formation	15	8.13e-01	-3.54e-02	9.38e-01
GO:0030324 lung development	35	7.17e-01	3.54e-02	9.17e-01
GO:0030507 spectrin binding	12	8.33e-01	-3.52e-02	9.44e-01
GO:0034976 response to endoplasmic reticulum stress	34	7.24e-01	3.50e-02	9.18e-01
GO:0098719 sodium ion import across plasma membrane	10	8.48e-01	3.50e-02	9.47e-01
GO:0045672 positive regulation of osteoclast differentiation	11	8.42e-01	-3.48e-02	9.44e-01
GO:0005525 GTP binding	212	3.85e-01	3.47e-02	7.50e-01
GO:0043025 neuronal cell body	85	5.81e-01	3.47e-02	8.53e-01
GO:0000956 nuclear-transcribed mRNA catabolic process	12	8.35e-01	-3.47e-02	9.44e-01
GO:0007346 regulation of mitotic cell cycle	31	7.38e-01	3.47e-02	9.20e-01
GO:0016055 Wnt signaling pathway	77	6.01e-01	3.45e-02	8.59e-01
GO:0003785 actin monomer binding	14	8.23e-01	3.45e-02	9.42e-01
GO:0008203 cholesterol metabolic process	28	7.55e-01	-3.41e-02	9.20e-01
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	28	7.55e-01	-3.41e-02	9.20e-01
GO:0003688 DNA replication origin binding	12	8.38e-01	-3.41e-02	9.44e-01
GO:0001778 plasma membrane repair	16	8.14e-01	-3.41e-02	9.38e-01
GO:0001889 liver development	30	7.48e-01	3.39e-02	9.20e-01
GO:0007288 sperm axoneme assembly	18	8.03e-01	-3.39e-02	9.36e-01
GO:0008340 determination of adult lifespan	21	7.89e-01	3.38e-02	9.29e-01
GO:0008270 zinc ion binding	399	2.52e-01	-3.36e-02	6.33e-01
GO:0042470 melanosome	27	7.63e-01	3.35e-02	9.20e-01
GO:0031594 neuromuscular junction	34	7.36e-01	3.35e-02	9.20e-01
GO:0005881 cytoplasmic microtubule	30	7.54e-01	3.31e-02	9.20e-01
GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels	16	8.19e-01	3.30e-02	9.41e-01
GO:0007416 synapse assembly	25	7.76e-01	-3.29e-02	9.25e-01
GO:1904047 S-adenosyl-L-methionine binding	13	8.37e-01	-3.29e-02	9.44e-01
GO:0007519 skeletal muscle tissue development	17	8.14e-01	3.29e-02	9.38e-01
GO:0032588 trans-Golgi network membrane	27	7.67e-01	3.29e-02	9.23e-01
GO:0004674 protein serine/threonine kinase activity	204	4.21e-01	-3.28e-02	7.73e-01
GO:0043235 receptor complex	75	6.25e-01	3.27e-02	8.76e-01
GO:0006887 exocytosis	44	7.08e-01	-3.26e-02	9.14e-01
GO:0048821 erythrocyte development	15	8.27e-01	-3.25e-02	9.44e-01
GO:0051457 maintenance of protein location in nucleus	10	8.59e-01	-3.25e-02	9.53e-01
GO:0030145 manganese ion binding	45	7.09e-01	-3.21e-02	9.14e-01
GO:0010811 positive regulation of cell-substrate adhesion	13	8.41e-01	-3.21e-02	9.44e-01
GO:0001673 male germ cell nucleus	27	7.74e-01	3.19e-02	9.25e-01
GO:0140823 histone H2BS36 kinase activity	31	7.59e-01	3.19e-02	9.20e-01
GO:0009636 response to toxic substance	15	8.31e-01	-3.18e-02	9.44e-01
GO:0007283 spermatogenesis	100	5.84e-01	3.17e-02	8.55e-01
GO:0031593 polyubiquitin modification-dependent protein binding	19	8.11e-01	-3.17e-02	9.38e-01
GO:0035402 histone H3T11 kinase activity	30	7.65e-01	3.16e-02	9.20e-01
GO:0044022 histone H3S28 kinase activity	30	7.65e-01	3.16e-02	9.20e-01
GO:0044023 histone H4S1 kinase activity	30	7.65e-01	3.16e-02	9.20e-01
GO:0044024 histone H2AS1 kinase activity	30	7.65e-01	3.16e-02	9.20e-01
GO:0044025 histone H2BS14 kinase activity	30	7.65e-01	3.16e-02	9.20e-01
GO:0072371 histone H2AS121 kinase activity	30	7.65e-01	3.16e-02	9.20e-01
GO:0140855 histone H3S57 kinase activity	30	7.65e-01	3.16e-02	9.20e-01
GO:0140857 histone H3T45 kinase activity	30	7.65e-01	3.16e-02	9.20e-01
GO:0060586 multicellular organismal-level iron ion homeostasis	15	8.32e-01	-3.16e-02	9.44e-01
GO:0016328 lateral plasma membrane	24	7.89e-01	-3.16e-02	9.29e-01
GO:0016197 endosomal transport	27	7.77e-01	3.15e-02	9.25e-01
GO:0043542 endothelial cell migration	14	8.39e-01	-3.14e-02	9.44e-01
GO:0030308 negative regulation of cell growth	42	7.25e-01	-3.14e-02	9.18e-01
GO:0001755 neural crest cell migration	25	7.86e-01	-3.14e-02	9.28e-01
GO:0030217 T cell differentiation	18	8.19e-01	-3.12e-02	9.41e-01
GO:0046326 positive regulation of D-glucose import	15	8.35e-01	3.10e-02	9.44e-01
GO:0060391 positive regulation of SMAD protein signal transduction	13	8.47e-01	3.09e-02	9.47e-01
GO:0045944 positive regulation of transcription by RNA polymerase II	528	2.30e-01	-3.07e-02	6.06e-01
GO:0005262 calcium channel activity	22	8.04e-01	3.06e-02	9.36e-01
GO:0006446 regulation of translational initiation	17	8.28e-01	-3.04e-02	9.44e-01
GO:0120162 positive regulation of cold-induced thermogenesis	28	7.81e-01	3.03e-02	9.26e-01
GO:0008013 beta-catenin binding	46	7.23e-01	3.03e-02	9.18e-01
GO:0001818 negative regulation of cytokine production	11	8.62e-01	-3.02e-02	9.55e-01
GO:0044297 cell body	25	7.94e-01	3.02e-02	9.34e-01
GO:0019843 rRNA binding	22	8.07e-01	-3.02e-02	9.37e-01
GO:0000724 double-strand break repair via homologous recombination	71	6.61e-01	-3.02e-02	8.99e-01
GO:0005923 bicellular tight junction	50	7.14e-01	3.00e-02	9.16e-01
GO:0050767 regulation of neurogenesis	14	8.46e-01	-3.00e-02	9.47e-01
GO:0042802 identical protein binding	663	1.93e-01	2.99e-02	5.66e-01
GO:0019722 calcium-mediated signaling	31	7.76e-01	-2.96e-02	9.25e-01
GO:0062023 collagen-containing extracellular matrix	74	6.61e-01	2.95e-02	8.99e-01
GO:0005112 Notch binding	13	8.54e-01	2.94e-02	9.51e-01
GO:0045121 membrane raft	74	6.64e-01	2.93e-02	8.99e-01
GO:0005543 phospholipid binding	37	7.60e-01	-2.90e-02	9.20e-01
GO:0005847 mRNA cleavage and polyadenylation specificity factor complex	11	8.69e-01	-2.88e-02	9.55e-01
GO:0003007 heart morphogenesis	16	8.42e-01	2.88e-02	9.44e-01
GO:0009952 anterior/posterior pattern specification	42	7.47e-01	2.88e-02	9.20e-01
GO:0006884 cell volume homeostasis	14	8.53e-01	-2.87e-02	9.51e-01
GO:0050821 protein stabilization	109	6.06e-01	-2.86e-02	8.59e-01
GO:0010467 gene expression	83	6.55e-01	2.84e-02	8.96e-01
GO:0010575 positive regulation of vascular endothelial growth factor production	13	8.60e-01	2.83e-02	9.53e-01
GO:0032991 protein-containing complex	206	4.85e-01	2.83e-02	8.02e-01
GO:0065003 protein-containing complex assembly	38	7.64e-01	-2.82e-02	9.20e-01
GO:0005484 SNAP receptor activity	26	8.04e-01	-2.81e-02	9.36e-01
GO:0071007 U2-type catalytic step 2 spliceosome	24	8.12e-01	-2.81e-02	9.38e-01
GO:0016251 RNA polymerase II general transcription initiation factor activity	22	8.20e-01	-2.81e-02	9.41e-01
GO:0038109 Kit signaling pathway	14	8.56e-01	-2.81e-02	9.52e-01
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	12	8.66e-01	2.81e-02	9.55e-01
GO:0071456 cellular response to hypoxia	33	7.83e-01	2.77e-02	9.26e-01
GO:0006284 base-excision repair	17	8.45e-01	-2.74e-02	9.46e-01
GO:0001503 ossification	26	8.10e-01	-2.73e-02	9.38e-01
GO:0019899 enzyme binding	110	6.22e-01	2.72e-02	8.74e-01
GO:0016925 protein sumoylation	19	8.37e-01	-2.72e-02	9.44e-01
GO:0005829 cytosol	2016	5.00e-02	2.72e-02	3.16e-01
GO:0046332 SMAD binding	23	8.22e-01	-2.70e-02	9.42e-01
GO:0051604 protein maturation	20	8.34e-01	-2.70e-02	9.44e-01
GO:0015630 microtubule cytoskeleton	69	6.99e-01	2.70e-02	9.11e-01
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation	30	8.00e-01	2.67e-02	9.35e-01
GO:0070085 glycosylation	14	8.63e-01	2.66e-02	9.55e-01
GO:0048538 thymus development	22	8.30e-01	-2.65e-02	9.44e-01
GO:0099170 postsynaptic modulation of chemical synaptic transmission	13	8.69e-01	-2.64e-02	9.55e-01
GO:0042734 presynaptic membrane	35	7.87e-01	-2.64e-02	9.28e-01
GO:0007186 G protein-coupled receptor signaling pathway	92	6.64e-01	-2.63e-02	8.99e-01
GO:0007015 actin filament organization	71	7.03e-01	2.62e-02	9.12e-01
GO:0005085 guanyl-nucleotide exchange factor activity	143	5.90e-01	-2.62e-02	8.58e-01
GO:0005179 hormone activity	12	8.77e-01	2.59e-02	9.59e-01
GO:0004679 AMP-activated protein kinase activity	32	8.02e-01	2.57e-02	9.35e-01
GO:0030332 cyclin binding	20	8.43e-01	2.56e-02	9.45e-01
GO:0003730 mRNA 3’-UTR binding	51	7.52e-01	2.56e-02	9.20e-01
GO:0009954 proximal/distal pattern formation	14	8.70e-01	-2.53e-02	9.56e-01
GO:0004181 metallocarboxypeptidase activity	12	8.81e-01	-2.50e-02	9.60e-01
GO:0048741 skeletal muscle fiber development	16	8.63e-01	-2.49e-02	9.55e-01
GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway	16	8.65e-01	-2.46e-02	9.55e-01
GO:0002244 hematopoietic progenitor cell differentiation	35	8.01e-01	-2.46e-02	9.35e-01
GO:0045880 positive regulation of smoothened signaling pathway	23	8.39e-01	-2.45e-02	9.44e-01
GO:0090575 RNA polymerase II transcription regulator complex	53	7.58e-01	-2.45e-02	9.20e-01
GO:0042752 regulation of circadian rhythm	27	8.27e-01	-2.44e-02	9.44e-01
GO:0035023 regulation of Rho protein signal transduction	16	8.67e-01	-2.41e-02	9.55e-01
GO:0005007 fibroblast growth factor receptor activity	13	8.81e-01	2.40e-02	9.60e-01
GO:1990573 potassium ion import across plasma membrane	18	8.60e-01	-2.40e-02	9.53e-01
GO:0106310 protein serine kinase activity	38	7.98e-01	2.40e-02	9.35e-01
GO:0030326 embryonic limb morphogenesis	14	8.77e-01	2.39e-02	9.59e-01
GO:0044877 protein-containing complex binding	105	6.73e-01	2.39e-02	9.00e-01
GO:0046540 U4/U6 x U5 tri-snRNP complex	23	8.45e-01	-2.36e-02	9.46e-01
GO:0098552 side of membrane	16	8.71e-01	-2.35e-02	9.56e-01
GO:0051017 actin filament bundle assembly	12	8.88e-01	2.34e-02	9.64e-01
GO:0090398 cellular senescence	19	8.61e-01	-2.32e-02	9.54e-01
GO:0019216 regulation of lipid metabolic process	10	8.99e-01	-2.32e-02	9.69e-01
GO:0019905 syntaxin binding	25	8.41e-01	2.31e-02	9.44e-01
GO:0009897 external side of plasma membrane	108	6.80e-01	2.30e-02	9.02e-01
GO:0048013 ephrin receptor signaling pathway	24	8.47e-01	-2.27e-02	9.47e-01
GO:0048012 hepatocyte growth factor receptor signaling pathway	17	8.73e-01	-2.25e-02	9.57e-01
GO:1990244 histone H2AT120 kinase activity	31	8.29e-01	2.24e-02	9.44e-01
GO:0006611 protein export from nucleus	22	8.56e-01	-2.23e-02	9.52e-01
GO:0035371 microtubule plus-end	12	8.94e-01	2.22e-02	9.67e-01
GO:0005524 ATP binding	894	2.73e-01	-2.19e-02	6.58e-01
GO:0050727 regulation of inflammatory response	26	8.48e-01	2.17e-02	9.47e-01
GO:0007219 Notch signaling pathway	41	8.12e-01	2.15e-02	9.38e-01
GO:0031167 rRNA methylation	11	9.04e-01	2.11e-02	9.72e-01
GO:0010468 regulation of gene expression	58	7.83e-01	2.09e-02	9.26e-01
GO:0043204 perikaryon	36	8.28e-01	2.09e-02	9.44e-01
GO:0060324 face development	14	8.93e-01	-2.08e-02	9.67e-01
GO:0031116 positive regulation of microtubule polymerization	11	9.05e-01	-2.08e-02	9.72e-01
GO:0043525 positive regulation of neuron apoptotic process	18	8.80e-01	-2.06e-02	9.60e-01
GO:0051607 defense response to virus	56	7.91e-01	-2.05e-02	9.31e-01
GO:0044389 ubiquitin-like protein ligase binding	16	8.87e-01	-2.05e-02	9.64e-01
GO:0005875 microtubule associated complex	10	9.12e-01	-2.02e-02	9.76e-01
GO:0005912 adherens junction	68	7.74e-01	-2.01e-02	9.25e-01
GO:0005911 cell-cell junction	77	7.61e-01	-2.01e-02	9.20e-01
GO:0042995 cell projection	54	7.99e-01	2.01e-02	9.35e-01
GO:0070936 protein K48-linked ubiquitination	68	7.77e-01	1.99e-02	9.25e-01
GO:0045785 positive regulation of cell adhesion	15	8.94e-01	1.99e-02	9.67e-01
GO:0051289 protein homotetramerization	35	8.42e-01	-1.95e-02	9.44e-01
GO:0030890 positive regulation of B cell proliferation	21	8.78e-01	1.94e-02	9.60e-01
GO:0060337 type I interferon-mediated signaling pathway	10	9.16e-01	-1.93e-02	9.77e-01
GO:1990138 neuron projection extension	10	9.17e-01	1.91e-02	9.77e-01
GO:0030659 cytoplasmic vesicle membrane	43	8.28e-01	1.91e-02	9.44e-01
GO:0043588 skin development	23	8.75e-01	1.89e-02	9.59e-01
GO:0030154 cell differentiation	141	7.00e-01	-1.88e-02	9.11e-01
GO:0035175 histone H3S10 kinase activity	31	8.58e-01	1.86e-02	9.53e-01
GO:0072354 histone H3T3 kinase activity	31	8.58e-01	1.86e-02	9.53e-01
GO:0005019 platelet-derived growth factor beta-receptor activity	13	9.08e-01	-1.85e-02	9.73e-01
GO:0003697 single-stranded DNA binding	67	7.95e-01	1.84e-02	9.34e-01
GO:0019005 SCF ubiquitin ligase complex	43	8.36e-01	-1.83e-02	9.44e-01
GO:0032874 positive regulation of stress-activated MAPK cascade	11	9.16e-01	1.83e-02	9.77e-01
GO:0030165 PDZ domain binding	29	8.65e-01	-1.83e-02	9.55e-01
GO:0030032 lamellipodium assembly	21	8.85e-01	-1.82e-02	9.63e-01
GO:0051015 actin filament binding	118	7.34e-01	-1.81e-02	9.20e-01
GO:0008021 synaptic vesicle	47	8.30e-01	1.81e-02	9.44e-01
GO:0043066 negative regulation of apoptotic process	151	7.02e-01	1.81e-02	9.12e-01
GO:0055085 transmembrane transport	88	7.70e-01	1.81e-02	9.24e-01
GO:0008233 peptidase activity	10	9.23e-01	-1.77e-02	9.79e-01
GO:0016301 kinase activity	14	9.09e-01	-1.77e-02	9.73e-01
GO:0043065 positive regulation of apoptotic process	122	7.36e-01	1.77e-02	9.20e-01
GO:0038062 protein tyrosine kinase collagen receptor activity	13	9.13e-01	-1.75e-02	9.76e-01
GO:0001223 transcription coactivator binding	21	8.90e-01	-1.74e-02	9.65e-01
GO:0098761 cellular response to interleukin-7	10	9.25e-01	1.73e-02	9.80e-01
GO:0045296 cadherin binding	28	8.75e-01	1.72e-02	9.59e-01
GO:0051082 unfolded protein binding	56	8.24e-01	-1.72e-02	9.42e-01
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	16	9.06e-01	-1.71e-02	9.73e-01
GO:0031267 small GTPase binding	166	7.07e-01	1.69e-02	9.14e-01
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors	18	9.01e-01	1.69e-02	9.71e-01
GO:0006635 fatty acid beta-oxidation	26	8.83e-01	1.66e-02	9.62e-01
GO:0005634 nucleus	2132	2.22e-01	-1.65e-02	5.97e-01
GO:0005685 U1 snRNP	12	9.21e-01	-1.64e-02	9.78e-01
GO:0016042 lipid catabolic process	29	8.79e-01	-1.63e-02	9.60e-01
GO:0035855 megakaryocyte development	10	9.29e-01	1.62e-02	9.80e-01
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator	11	9.26e-01	1.61e-02	9.80e-01
GO:0060339 negative regulation of type I interferon-mediated signaling pathway	13	9.21e-01	1.60e-02	9.78e-01
GO:0042130 negative regulation of T cell proliferation	12	9.26e-01	1.56e-02	9.80e-01
GO:0004222 metalloendopeptidase activity	50	8.50e-01	-1.55e-02	9.48e-01
GO:0008083 growth factor activity	39	8.68e-01	1.54e-02	9.55e-01
GO:0000175 3’-5’-RNA exonuclease activity	21	9.04e-01	-1.53e-02	9.72e-01
GO:0048675 axon extension	16	9.16e-01	1.52e-02	9.77e-01
GO:0070527 platelet aggregation	16	9.18e-01	-1.48e-02	9.78e-01
GO:0071806 protein transmembrane transport	12	9.30e-01	1.47e-02	9.80e-01
GO:0000278 mitotic cell cycle	53	8.53e-01	1.47e-02	9.51e-01
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process	43	8.69e-01	-1.45e-02	9.55e-01
GO:0090141 positive regulation of mitochondrial fission	16	9.20e-01	1.45e-02	9.78e-01
GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction	35	8.84e-01	-1.42e-02	9.63e-01
GO:0006879 intracellular iron ion homeostasis	31	8.91e-01	1.42e-02	9.66e-01
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	32	8.90e-01	-1.41e-02	9.65e-01
GO:0005200 structural constituent of cytoskeleton	28	8.98e-01	1.40e-02	9.69e-01
GO:0007528 neuromuscular junction development	14	9.28e-01	1.40e-02	9.80e-01
GO:0008344 adult locomotory behavior	23	9.08e-01	-1.39e-02	9.73e-01
GO:0003690 double-stranded DNA binding	35	8.88e-01	-1.38e-02	9.64e-01
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding	394	6.43e-01	-1.37e-02	8.88e-01
GO:0006783 heme biosynthetic process	10	9.40e-01	1.37e-02	9.83e-01
GO:0016446 somatic hypermutation of immunoglobulin genes	10	9.41e-01	1.35e-02	9.83e-01
GO:0003756 protein disulfide isomerase activity	10	9.41e-01	-1.35e-02	9.83e-01
GO:0001843 neural tube closure	48	8.72e-01	-1.34e-02	9.57e-01
GO:0030335 positive regulation of cell migration	107	8.14e-01	1.32e-02	9.38e-01
GO:0005080 protein kinase C binding	16	9.28e-01	-1.31e-02	9.80e-01
GO:0097110 scaffold protein binding	27	9.07e-01	-1.30e-02	9.73e-01
GO:0035979 histone H2AXS139 kinase activity	32	8.99e-01	-1.30e-02	9.69e-01
GO:0002053 positive regulation of mesenchymal cell proliferation	11	9.41e-01	-1.29e-02	9.83e-01
GO:0042407 cristae formation	11	9.41e-01	1.28e-02	9.83e-01
GO:0007286 spermatid development	25	9.13e-01	1.26e-02	9.76e-01
GO:2000737 negative regulation of stem cell differentiation	12	9.40e-01	-1.26e-02	9.83e-01
GO:0051881 regulation of mitochondrial membrane potential	14	9.36e-01	-1.25e-02	9.83e-01
GO:0061564 axon development	13	9.38e-01	1.24e-02	9.83e-01
GO:0001678 intracellular glucose homeostasis	17	9.30e-01	1.24e-02	9.80e-01
GO:0043524 negative regulation of neuron apoptotic process	51	8.81e-01	-1.21e-02	9.60e-01
GO:0030521 androgen receptor signaling pathway	12	9.42e-01	1.21e-02	9.83e-01
GO:0008045 motor neuron axon guidance	12	9.44e-01	1.18e-02	9.83e-01
GO:0001541 ovarian follicle development	19	9.30e-01	1.16e-02	9.80e-01
GO:0045862 positive regulation of proteolysis	12	9.45e-01	1.15e-02	9.83e-01
GO:0046676 negative regulation of insulin secretion	10	9.50e-01	-1.15e-02	9.84e-01
GO:0032526 response to retinoic acid	15	9.39e-01	-1.14e-02	9.83e-01
GO:0000460 maturation of 5.8S rRNA	11	9.50e-01	1.10e-02	9.84e-01
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	15	9.42e-01	-1.08e-02	9.83e-01
GO:0008286 insulin receptor signaling pathway	49	8.96e-01	1.08e-02	9.67e-01
GO:0001702 gastrulation with mouth forming second	10	9.53e-01	-1.08e-02	9.84e-01
GO:0022904 respiratory electron transport chain	14	9.45e-01	-1.07e-02	9.83e-01
GO:0006310 DNA recombination	23	9.29e-01	-1.07e-02	9.80e-01
GO:0016529 sarcoplasmic reticulum	13	9.47e-01	1.06e-02	9.84e-01
GO:0000118 histone deacetylase complex	22	9.33e-01	1.03e-02	9.81e-01
GO:0070062 extracellular exosome	39	9.14e-01	-1.00e-02	9.76e-01
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway	33	9.22e-01	9.90e-03	9.78e-01
GO:0007254 JNK cascade	26	9.30e-01	-9.89e-03	9.80e-01
GO:0005201 extracellular matrix structural constituent	13	9.51e-01	9.84e-03	9.84e-01
GO:0035556 intracellular signal transduction	186	8.18e-01	-9.82e-03	9.41e-01
GO:0001822 kidney development	51	9.04e-01	-9.77e-03	9.72e-01
GO:0004672 protein kinase activity	64	8.96e-01	9.49e-03	9.67e-01
GO:0031297 replication fork processing	26	9.34e-01	-9.45e-03	9.81e-01
GO:0006298 mismatch repair	16	9.49e-01	-9.31e-03	9.84e-01
GO:0014032 neural crest cell development	11	9.58e-01	9.18e-03	9.84e-01
GO:0097550 transcription preinitiation complex	12	9.56e-01	-9.14e-03	9.84e-01
GO:0031463 Cul3-RING ubiquitin ligase complex	41	9.20e-01	-9.09e-03	9.78e-01
GO:0004535 poly(A)-specific ribonuclease activity	10	9.60e-01	9.05e-03	9.85e-01
GO:0042149 cellular response to glucose starvation	29	9.33e-01	9.00e-03	9.81e-01
GO:0098656 monoatomic anion transmembrane transport	18	9.48e-01	8.88e-03	9.84e-01
GO:0005006 epidermal growth factor receptor activity	14	9.55e-01	8.78e-03	9.84e-01
GO:0045773 positive regulation of axon extension	10	9.62e-01	8.66e-03	9.86e-01
GO:1904263 positive regulation of TORC1 signaling	35	9.33e-01	-8.16e-03	9.81e-01
GO:0045765 regulation of angiogenesis	11	9.63e-01	7.98e-03	9.86e-01
GO:0047496 vesicle transport along microtubule	11	9.64e-01	7.97e-03	9.86e-01
GO:0051209 release of sequestered calcium ion into cytosol	20	9.52e-01	-7.70e-03	9.84e-01
GO:0051496 positive regulation of stress fiber assembly	31	9.41e-01	-7.67e-03	9.83e-01
GO:0042552 myelination	28	9.44e-01	-7.61e-03	9.83e-01
GO:0032154 cleavage furrow	28	9.45e-01	-7.55e-03	9.83e-01
GO:0009411 response to UV	23	9.51e-01	-7.45e-03	9.84e-01
GO:0031252 cell leading edge	20	9.55e-01	7.31e-03	9.84e-01
GO:0005506 iron ion binding	64	9.20e-01	-7.24e-03	9.78e-01
GO:0031464 Cul4A-RING E3 ubiquitin ligase complex	10	9.70e-01	6.98e-03	9.88e-01
GO:0005876 spindle microtubule	20	9.57e-01	6.95e-03	9.84e-01
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle	26	9.51e-01	-6.95e-03	9.84e-01
GO:0005763 mitochondrial small ribosomal subunit	21	9.59e-01	-6.55e-03	9.84e-01
GO:0051301 cell division	144	8.94e-01	6.41e-03	9.67e-01
GO:0004722 protein serine/threonine phosphatase activity	33	9.50e-01	6.32e-03	9.84e-01
GO:0030501 positive regulation of bone mineralization	14	9.67e-01	-6.31e-03	9.88e-01
GO:0010507 negative regulation of autophagy	22	9.59e-01	-6.28e-03	9.84e-01
GO:0038084 vascular endothelial growth factor signaling pathway	23	9.59e-01	-6.18e-03	9.84e-01
GO:0055013 cardiac muscle cell development	11	9.72e-01	6.13e-03	9.88e-01
GO:0046580 negative regulation of Ras protein signal transduction	13	9.70e-01	6.11e-03	9.88e-01
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific	183	8.88e-01	6.05e-03	9.64e-01
GO:0004677 DNA-dependent protein kinase activity	31	9.54e-01	5.97e-03	9.84e-01
GO:0035116 embryonic hindlimb morphogenesis	12	9.72e-01	5.80e-03	9.88e-01
GO:0043488 regulation of mRNA stability	16	9.69e-01	-5.67e-03	9.88e-01
GO:0043124 negative regulation of canonical NF-kappaB signal transduction	36	9.54e-01	-5.58e-03	9.84e-01
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific	348	8.65e-01	5.33e-03	9.55e-01
GO:0005819 spindle	54	9.47e-01	-5.24e-03	9.84e-01
GO:0033173 calcineurin-NFAT signaling cascade	10	9.78e-01	5.14e-03	9.92e-01
GO:0051225 spindle assembly	21	9.68e-01	5.11e-03	9.88e-01
GO:0005834 heterotrimeric G-protein complex	19	9.70e-01	5.04e-03	9.88e-01
GO:0016579 protein deubiquitination	28	9.64e-01	-4.93e-03	9.86e-01
GO:0030522 intracellular receptor signaling pathway	18	9.71e-01	4.87e-03	9.88e-01
GO:0046835 carbohydrate phosphorylation	20	9.71e-01	-4.67e-03	9.88e-01
GO:0005657 replication fork	20	9.71e-01	4.67e-03	9.88e-01
GO:0036342 post-anal tail morphogenesis	11	9.79e-01	4.66e-03	9.92e-01
GO:0006417 regulation of translation	44	9.58e-01	-4.54e-03	9.84e-01
GO:0005737 cytoplasm	2177	7.80e-01	3.75e-03	9.26e-01
GO:0016323 basolateral plasma membrane	94	9.54e-01	-3.43e-03	9.84e-01
GO:0060021 roof of mouth development	36	9.73e-01	-3.26e-03	9.88e-01
GO:0090263 positive regulation of canonical Wnt signaling pathway	62	9.69e-01	2.84e-03	9.88e-01
GO:0000902 cell morphogenesis	55	9.76e-01	-2.33e-03	9.91e-01
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity	20	9.87e-01	2.12e-03	9.97e-01
GO:0043001 Golgi to plasma membrane protein transport	21	9.87e-01	2.04e-03	9.97e-01
GO:0019900 kinase binding	48	9.81e-01	1.96e-03	9.93e-01
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT	13	9.90e-01	1.91e-03	9.99e-01
GO:0008543 fibroblast growth factor receptor signaling pathway	36	9.85e-01	-1.85e-03	9.95e-01
GO:0005770 late endosome	75	9.79e-01	1.77e-03	9.92e-01
GO:0000165 MAPK cascade	46	9.84e-01	-1.75e-03	9.95e-01
GO:0006606 protein import into nucleus	62	9.81e-01	1.75e-03	9.93e-01
GO:0007020 microtubule nucleation	14	9.91e-01	-1.72e-03	9.99e-01
GO:0048863 stem cell differentiation	22	9.89e-01	-1.65e-03	9.98e-01
GO:0009566 fertilization	12	9.94e-01	-1.34e-03	9.99e-01
GO:0030490 maturation of SSU-rRNA	12	9.94e-01	-1.33e-03	9.99e-01
GO:0045599 negative regulation of fat cell differentiation	21	9.92e-01	-1.23e-03	9.99e-01
GO:1990498 mitotic spindle microtubule	10	9.96e-01	-8.89e-04	9.99e-01
GO:0051537 2 iron, 2 sulfur cluster binding	17	9.95e-01	-8.79e-04	9.99e-01
GO:0000124 SAGA complex	15	9.96e-01	8.02e-04	9.99e-01
GO:0032418 lysosome localization	23	9.96e-01	-6.14e-04	9.99e-01
GO:0031526 brush border membrane	12	9.97e-01	6.02e-04	9.99e-01
GO:0007173 epidermal growth factor receptor signaling pathway	38	9.96e-01	-4.65e-04	9.99e-01
GO:0045499 chemorepellent activity	18	9.97e-01	-4.56e-04	9.99e-01
GO:0031290 retinal ganglion cell axon guidance	11	9.99e-01	-2.97e-04	1.00e+00
GO:0045211 postsynaptic membrane	54	9.97e-01	2.71e-04	9.99e-01
GO:0005868 cytoplasmic dynein complex	14	9.99e-01	1.69e-04	1.00e+00
GO:0003743 translation initiation factor activity	39	1.00e+00	-2.68e-05	1.00e+00

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Detailed Gene set reports

GO:0022625 cytosolic large ribosomal subunit

set	GO:0022625 cytosolic large ribosomal subunit
setSize	40
pANOVA	9.25e-18
s.dist	0.784
p.adjustANOVA	8.18e-15

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL13	7069
RPL35	6982
RPL3	6968
RPL9	6964
RPL7A	6916
RPL7	6799
RPL37	6798
RPL14	6726
RPL27A	6708
RPL30	6706
RPL34	6677
RPL26L1	6669
RPL27	6627
RPLP0	6605
RPL8	6596
RPL15	6589
RPL29	6557
RPL32	6549
RPL11	6521
RPL10A	6516

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL13	7069
RPL35	6982
RPL3	6968
RPL9	6964
RPL7A	6916
RPL7	6799
RPL37	6798
RPL14	6726
RPL27A	6708
RPL30	6706
RPL34	6677
RPL26L1	6669
RPL27	6627
RPLP0	6605
RPL8	6596
RPL15	6589
RPL29	6557
RPL32	6549
RPL11	6521
RPL10A	6516
RPL5	6494
RPL31	6482
RPL37A	6449
RPL18A	6408
RPL38	6299
RPLP1	6158
RPL7L1	5840
RPL35A	5806
RPLP2	5784
RPL23A	5487
RPL6	5308
RPL23	5046
RPL21	4780
RPL36	4487
RPL12	4336
RPL19	4230
RPL3L	3915
RPL24	3427
RPL4	-3483
ZCCHC17	-6836

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GO:0035145 exon-exon junction complex

set	GO:0035145 exon-exon junction complex
setSize	10
pANOVA	5.17e-05
s.dist	-0.739
p.adjustANOVA	0.00609

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SRSF1	-7039
SMG6	-6999
UPF1	-6958
PNN	-6956
UPF2	-6374
CASC3	-6299
TDRD3	-5386
THRAP3	-3852
UPF3B	-3600
UPF3A	-763

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SRSF1	-7039
SMG6	-6999
UPF1	-6958
PNN	-6956
UPF2	-6374
CASC3	-6299
TDRD3	-5386
THRAP3	-3852
UPF3B	-3600
UPF3A	-763

---

GO:0002181 cytoplasmic translation

set	GO:0002181 cytoplasmic translation
setSize	27
pANOVA	3.22e-11
s.dist	0.738
p.adjustANOVA	1.42e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL9	6964
RPS6	6917
RPS14	6779
RPL26L1	6669
RPLP0	6605
RPL8	6596
RPL15	6589
RPL29	6557
RPL10A	6516
RPS23	6499
RPL31	6482
RPL18A	6408
RPL38	6299
RPLP1	6158
RPL22	6069
RPL35A	5806
RPL6	5308
DRG2	4923
RPS28	4737
RPL36	4487

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL9	6964
RPS6	6917
RPS14	6779
RPL26L1	6669
RPLP0	6605
RPL8	6596
RPL15	6589
RPL29	6557
RPL10A	6516
RPS23	6499
RPL31	6482
RPL18A	6408
RPL38	6299
RPLP1	6158
RPL22	6069
RPL35A	5806
RPL6	5308
DRG2	4923
RPS28	4737
RPL36	4487
RPL22L1	4343
SARS1	3997
RWDD1	3612
RPS26	3480
RPS29	3463
RPL24	3427
ZC3H15	-5353

---

GO:0022627 cytosolic small ribosomal subunit

set	GO:0022627 cytosolic small ribosomal subunit
setSize	25
pANOVA	4.25e-10
s.dist	0.721
p.adjustANOVA	1.5e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS15A	7077
RPS2	7055
RPS4Y1	6998
RPS3A	6989
RPS12	6987
RPS6	6917
RPS7	6860
RPS3	6841
RPS20	6837
RPS15	6804
RPS14	6779
RPS13	6687
RPS21	6631
RPS23	6499
RPS8	6219
RPS24	6010
RPS16	5874
RPS11	5830
RPS28	4737
RPS10	4279

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS15A	7077
RPS2	7055
RPS4Y1	6998
RPS3A	6989
RPS12	6987
RPS6	6917
RPS7	6860
RPS3	6841
RPS20	6837
RPS15	6804
RPS14	6779
RPS13	6687
RPS21	6631
RPS23	6499
RPS8	6219
RPS24	6010
RPS16	5874
RPS11	5830
RPS28	4737
RPS10	4279
RPS26	3480
RPS29	3463
EIF2A	-11
RPS27L	-1653
LARP4	-7157

---

GO:1905564 positive regulation of vascular endothelial cell proliferation

set	GO:1905564 positive regulation of vascular endothelial cell proliferation
setSize	10
pANOVA	0.000473
s.dist	0.638
p.adjustANOVA	0.0299

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ITGA4	6997
FGFR1	6864
PLCG1	6678
SP1	6313
PDPK1	6060
SIRT6	3725
STAT3	3305
AKT3	2700
NRARP	1934
IGF2	324

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ITGA4	6997
FGFR1	6864
PLCG1	6678
SP1	6313
PDPK1	6060
SIRT6	3725
STAT3	3305
AKT3	2700
NRARP	1934
IGF2	324

---

GO:0036121 double-stranded DNA helicase activity

set	GO:0036121 double-stranded DNA helicase activity
setSize	11
pANOVA	0.000301
s.dist	-0.629
p.adjustANOVA	0.0232

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	-7261
UPF1	-6958
BLM	-6809
CHD1	-6268
MCM3	-5916
MCM9	-5677
IGHMBP2	-4341
ERCC3	-4320
CHD7	-4166
MCM8	-1095
MCM5	1865

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	-7261
UPF1	-6958
BLM	-6809
CHD1	-6268
MCM3	-5916
MCM9	-5677
IGHMBP2	-4341
ERCC3	-4320
CHD7	-4166
MCM8	-1095
MCM5	1865

---

GO:0004683 calcium/calmodulin-dependent protein kinase activity

set	GO:0004683 calcium/calmodulin-dependent protein kinase activity
setSize	11
pANOVA	0.000666
s.dist	0.593
p.adjustANOVA	0.0346

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MAPKAPK2	7075
CAMK2A	5501
MKNK2	5475
CAMK2D	5165
CAMK2G	5043
MAPKAPK5	4545
CAMK1	4231
MYLK3	3923
MAPKAPK3	2716
DAPK1	1150
CAMK1G	943

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All member genes

GeneID	Gene Rank
MAPKAPK2	7075
CAMK2A	5501
MKNK2	5475
CAMK2D	5165
CAMK2G	5043
MAPKAPK5	4545
CAMK1	4231
MYLK3	3923
MAPKAPK3	2716
DAPK1	1150
CAMK1G	943

---

GO:0004602 glutathione peroxidase activity

set	GO:0004602 glutathione peroxidase activity
setSize	12
pANOVA	0.000605
s.dist	0.572
p.adjustANOVA	0.0328

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CLIC2	6934
GPX3	6756
GPX7	6123
GPX4	6084
MGST1	5651
MGST3	5458
PRDX6	5307
CP	4132
GPX1	2712
GSTK1	982
PTGES	-119
GPX8	-1900

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CLIC2	6934
GPX3	6756
GPX7	6123
GPX4	6084
MGST1	5651
MGST3	5458
PRDX6	5307
CP	4132
GPX1	2712
GSTK1	982
PTGES	-119
GPX8	-1900

---

GO:1990391 DNA repair complex

set	GO:1990391 DNA repair complex
setSize	10
pANOVA	0.00355
s.dist	-0.532
p.adjustANOVA	0.091

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TP53BP1	-7130
FANCI	-7002
KDM1A	-6740
ASCC2	-6541
FANCD2	-5630
ATM	-5582
BRCA1	-3452
BRCA2	-1884
PHF21A	1823
PALB2	2788

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TP53BP1	-7130
FANCI	-7002
KDM1A	-6740
ASCC2	-6541
FANCD2	-5630
ATM	-5582
BRCA1	-3452
BRCA2	-1884
PHF21A	1823
PALB2	2788

---

GO:0140662 ATP-dependent protein folding chaperone

set	GO:0140662 ATP-dependent protein folding chaperone
setSize	23
pANOVA	1.17e-05
s.dist	-0.528
p.adjustANOVA	0.00207

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HSP90B1	-7247
HSPA8	-7240
HSP90AA1	-7185
CLPX	-7052
HSPA13	-7024
TOR1A	-6795
HSPH1	-6761
HSPA4	-6719
HYOU1	-6487
TCP1	-6174
CCT2	-6116
HSPD1	-5711
HSPA14	-5144
HSPA4L	-5009
CCT8	-4515
CCT4	-3256
CCT7	-2495
CCT3	-714
HSPA9	-707
CCT5	820

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HSP90B1	-7247
HSPA8	-7240
HSP90AA1	-7185
CLPX	-7052
HSPA13	-7024
TOR1A	-6795
HSPH1	-6761
HSPA4	-6719
HYOU1	-6487
TCP1	-6174
CCT2	-6116
HSPD1	-5711
HSPA14	-5144
HSPA4L	-5009
CCT8	-4515
CCT4	-3256
CCT7	-2495
CCT3	-714
HSPA9	-707
CCT5	820
HSPA2	1022
HSPA5	4190
TRAP1	6655

---

GO:0006623 protein targeting to vacuole

set	GO:0006623 protein targeting to vacuole
setSize	11
pANOVA	0.00278
s.dist	-0.521
p.adjustANOVA	0.0794

Top enriched genes

Top 20 genes

GeneID	Gene Rank
VPS37C	-6788
PIK3R4	-6534
VPS37B	-6221
VPS8	-5069
VPS13C	-4425
MON1A	-4210
VPS13D	-3699
VPS13A	-3524
VPS37A	-1780
VPS41	-867
GID4	758

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
VPS37C	-6788
PIK3R4	-6534
VPS37B	-6221
VPS8	-5069
VPS13C	-4425
MON1A	-4210
VPS13D	-3699
VPS13A	-3524
VPS37A	-1780
VPS41	-867
GID4	758

---

GO:0035925 mRNA 3’-UTR AU-rich region binding

set	GO:0035925 mRNA 3’-UTR AU-rich region binding
setSize	13
pANOVA	0.00141
s.dist	0.511
p.adjustANOVA	0.0534

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ZFP36L2	6237
EXOSC9	6218
FXR1	5628
NUDT21	5273
EXOSC8	5171
TIA1	4852
RBMS3	4739
ELAVL1	4492
MEX3D	4320
DHX36	1626
ZC3H12A	831
ARID5A	100
EXOSC7	-2999

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ZFP36L2	6237
EXOSC9	6218
FXR1	5628
NUDT21	5273
EXOSC8	5171
TIA1	4852
RBMS3	4739
ELAVL1	4492
MEX3D	4320
DHX36	1626
ZC3H12A	831
ARID5A	100
EXOSC7	-2999

---

GO:0003735 structural constituent of ribosome

set	GO:0003735 structural constituent of ribosome
setSize	118
pANOVA	1.19e-21
s.dist	0.509
p.adjustANOVA	2.1e-18

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS15A	7077
RPL13	7069
RPS2	7055
RPS4Y1	6998
RPS3A	6989
RPS12	6987
RPL35	6982
RPL3	6968
RPL9	6964
RPS6	6917
RPS7	6860
RPS3	6841
RPS20	6837
RPS15	6804
RPL7	6799
RPL37	6798
RPS14	6779
RPL14	6726
RPL27A	6708
RPL30	6706

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS15A	7077
RPL13	7069
RPS2	7055
RPS4Y1	6998
RPS3A	6989
RPS12	6987
RPL35	6982
RPL3	6968
RPL9	6964
RPS6	6917
RPS7	6860
RPS3	6841
RPS20	6837
RPS15	6804
RPL7	6799
RPL37	6798
RPS14	6779
RPL14	6726
RPL27A	6708
RPL30	6706
RPS13	6687
RPL34	6677
RPL26L1	6669
RPS21	6631
RPL27	6627
RPLP0	6605
RPL8	6596
RPL15	6589
RPL29	6557
RPL32	6549
RPL11	6521
RPL10A	6516
RPS23	6499
RPL5	6494
RPL31	6482
RPS27A	6472
RPL37A	6449
MRPL28	6425
RPL18A	6408
MRPS34	6378
RPL38	6299
RPS8	6219
RPLP1	6158
RPL22	6069
RPS24	6010
MRPS18A	5877
RPS16	5874
RPL7L1	5840
RPS11	5830
RPL35A	5806
RPLP2	5784
MRPL51	5613
MRPS17	5509
RPL23A	5487
RPL6	5308
MRPL37	5243
RPL23	5046
MRPL14	5041
RPS17	4996
MRPL35	4971
MRPL13	4938
MRPS21	4924
MRPL21	4790
RPL21	4780
MRPL24	4759
RPS28	4737
MRPL23	4659
MRPL32	4625
RPL36	4487
RPL22L1	4343
RPL12	4336
RPS10	4279
RPL19	4230
RPL3L	3915
MRPS23	3858
MRPL36	3731
MRPS6	3708
DAP3	3679
RPS26	3480
SRBD1	3464
RPS29	3463
RPL24	3427
UBA52	2851
MRPL41	2725
MRPL16	2640
MRPS12	1866
MRPL2	1147
MRPS5	1139
MRPL12	1132
MRPS16	1115
MRPL17	736
MRPS18C	541
MRPL18	209
MRPL19	-116
MRPS25	-120
MRPS22	-276
MRPS9	-291
MRPS31	-1044
MRPS30	-1212
DDA1	-1421
MRPL22	-1455
RPS27L	-1653
MRPL49	-2076
MRPL27	-2082
MRPL47	-2421
MRPL15	-2670
MRPL20	-2997
MRPS15	-3274
RPL4	-3483
MRPS35	-3829
MRPL3	-3897
MRPS14	-4706
MRPS10	-5167
MRPS11	-5388
MRPS7	-5430
MRPS2	-5503
MRPL10	-5940
MRPL46	-6861

---

GO:2000648 positive regulation of stem cell proliferation

set	GO:2000648 positive regulation of stem cell proliferation
setSize	12
pANOVA	0.00245
s.dist	0.505
p.adjustANOVA	0.0737

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GJA1	7040
FGFR1	6864
OSR2	6349
TBX3	6289
RUNX2	4689
FGF10	4121
SOX11	4085
HOXA3	3865
PTPRC	2824
PRRX1	638
HNRNPU	-1262
TP63	-3140

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GJA1	7040
FGFR1	6864
OSR2	6349
TBX3	6289
RUNX2	4689
FGF10	4121
SOX11	4085
HOXA3	3865
PTPRC	2824
PRRX1	638
HNRNPU	-1262
TP63	-3140

---

GO:0030127 COPII vesicle coat

set	GO:0030127 COPII vesicle coat
setSize	10
pANOVA	0.00588
s.dist	0.503
p.adjustANOVA	0.118

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SEC24D	6970
SEC31A	6526
SEC13	5919
PDCD6	5504
SEC23A	5401
SAR1B	4076
SEC24B	3007
PEF1	2133
SEC24A	1591
SEC31B	-5960

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SEC24D	6970
SEC31A	6526
SEC13	5919
PDCD6	5504
SEC23A	5401
SAR1B	4076
SEC24B	3007
PEF1	2133
SEC24A	1591
SEC31B	-5960

---

GO:0009378 four-way junction helicase activity

set	GO:0009378 four-way junction helicase activity
setSize	13
pANOVA	0.00181
s.dist	-0.5
p.adjustANOVA	0.0583

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	-7261
BLM	-6809
CHD1	-6268
RECQL	-6017
MCM3	-5916
MCM9	-5677
ERCC3	-4320
FANCM	-4283
CHD7	-4166
RECQL5	-2829
MCM8	-1095
MCM5	1865
WRN	4696

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	-7261
BLM	-6809
CHD1	-6268
RECQL	-6017
MCM3	-5916
MCM9	-5677
ERCC3	-4320
FANCM	-4283
CHD7	-4166
RECQL5	-2829
MCM8	-1095
MCM5	1865
WRN	4696

---

GO:0003724 RNA helicase activity

set	GO:0003724 RNA helicase activity
setSize	37
pANOVA	2.26e-07
s.dist	-0.492
p.adjustANOVA	5.83e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
DDX18	-7080
DDX54	-7028
DDX3X	-6959
UPF1	-6958
DDX24	-6929
DDX49	-6322
DDX46	-6289
DDX19	-6239
SNRNP200	-6166
DDX20	-6151
SUPV3L1	-6106
DDX6	-5874
DDX55	-5766
EIF4A2	-5736
DDX42	-5526
DHX30	-5231
DHX58	-5117
DHX29	-4851
DDX52	-4670
DDX25	-4303

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
DDX18	-7080
DDX54	-7028
DDX3X	-6959
UPF1	-6958
DDX24	-6929
DDX49	-6322
DDX46	-6289
DDX19	-6239
SNRNP200	-6166
DDX20	-6151
SUPV3L1	-6106
DDX6	-5874
DDX55	-5766
EIF4A2	-5736
DDX42	-5526
DHX30	-5231
DHX58	-5117
DHX29	-4851
DDX52	-4670
DDX25	-4303
FANCM	-4283
DHX8	-4231
G3BP1	-4034
DHX15	-3570
DDX41	-3521
DDX47	-3354
SKIV2L2	-2915
DDX1	-2819
IFIH1	-1488
DDX5	-400
DDX59	213
DDX28	225
DDX27	465
DHX36	1626
DDX10	2973
DDX17	4152
EIF4A3	5731

---

GO:0008593 regulation of Notch signaling pathway

set	GO:0008593 regulation of Notch signaling pathway
setSize	10
pANOVA	0.00723
s.dist	0.491
p.adjustANOVA	0.129

Top enriched genes

Top 20 genes

GeneID	Gene Rank
POFUT1	6632
LLGL1	6358
LLGL2	6355
RFNG	6269
ADAM10	5707
LFNG	5693
TSPEAR	2831
GALNT11	1423
PRAG1	-152
POSTN	-6852

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
POFUT1	6632
LLGL1	6358
LLGL2	6355
RFNG	6269
ADAM10	5707
LFNG	5693
TSPEAR	2831
GALNT11	1423
PRAG1	-152
POSTN	-6852

---

GO:1990518 single-stranded 3’-5’ DNA helicase activity

set	GO:1990518 single-stranded 3’-5’ DNA helicase activity
setSize	11
pANOVA	0.00538
s.dist	-0.485
p.adjustANOVA	0.114

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	-7261
BLM	-6809
CHD1	-6268
MCM6	-5993
MCM3	-5916
MCM9	-5677
ERCC3	-4320
CHD7	-4166
MCM8	-1095
MCM5	1865
HELQ	6135

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	-7261
BLM	-6809
CHD1	-6268
MCM6	-5993
MCM3	-5916
MCM9	-5677
ERCC3	-4320
CHD7	-4166
MCM8	-1095
MCM5	1865
HELQ	6135

---

GO:0140861 DNA repair-dependent chromatin remodeling

set	GO:0140861 DNA repair-dependent chromatin remodeling
setSize	14
pANOVA	0.00173
s.dist	-0.484
p.adjustANOVA	0.0569

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KDM1A	-6740
SIRT1	-6303
BRCC3	-5466
DTX3L	-5280
RNF8	-4844
RNF168	-4768
TRRAP	-4536
HDAC3	-4263
HDGFRP2	-3807
UBR5	-2479
USP3	-2228
UIMC1	-646
HPF1	-452
BABAM1	1663

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KDM1A	-6740
SIRT1	-6303
BRCC3	-5466
DTX3L	-5280
RNF8	-4844
RNF168	-4768
TRRAP	-4536
HDAC3	-4263
HDGFRP2	-3807
UBR5	-2479
USP3	-2228
UIMC1	-646
HPF1	-452
BABAM1	1663

---

GO:0003678 DNA helicase activity

set	GO:0003678 DNA helicase activity
setSize	20
pANOVA	0.000196
s.dist	-0.481
p.adjustANOVA	0.0182

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	-7261
MRE11	-6783
RTEL1	-6392
SNRNP200	-6166
SUPV3L1	-6106
MCM6	-5993
CHD1L	-5881
MCM9	-5677
DHX30	-5231
BRIP1	-4296
G3BP1	-4034
RUVBL1	-3735
RECQL5	-2829
DNA2	-2811
RAD50	-2426
MCM4	-1320
DDX11	93
XRCC5	1145
DHX36	1626
XRCC6	2819

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	-7261
MRE11	-6783
RTEL1	-6392
SNRNP200	-6166
SUPV3L1	-6106
MCM6	-5993
CHD1L	-5881
MCM9	-5677
DHX30	-5231
BRIP1	-4296
G3BP1	-4034
RUVBL1	-3735
RECQL5	-2829
DNA2	-2811
RAD50	-2426
MCM4	-1320
DDX11	93
XRCC5	1145
DHX36	1626
XRCC6	2819

---

GO:0097038 perinuclear endoplasmic reticulum

set	GO:0097038 perinuclear endoplasmic reticulum
setSize	10
pANOVA	0.00892
s.dist	0.478
p.adjustANOVA	0.143

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CAPN2	6958
OSBPL3	6491
OSBP2	6061
OSBPL2	5845
CISD2	4973
OSBPL6	2818
OSBP	2659
OSBPL7	2652
TRIM13	-1190
OSBPL1A	-3932

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CAPN2	6958
OSBPL3	6491
OSBP2	6061
OSBPL2	5845
CISD2	4973
OSBPL6	2818
OSBP	2659
OSBPL7	2652
TRIM13	-1190
OSBPL1A	-3932

---

GO:0005544 calcium-dependent phospholipid binding

set	GO:0005544 calcium-dependent phospholipid binding
setSize	21
pANOVA	0.000169
s.dist	0.474
p.adjustANOVA	0.0166

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ANXA1	7067
ANXA6	7019
CPNE1	6981
ESYT1	6579
C2CD5	6477
ANXA11	6474
CPNE2	6448
ANXA5	6410
ANXA13	5824
SYT17	5427
ANXA2	5074
ANXA7	3561
ESYT2	3293
CPNE3	3022
SYT13	2523
CPNE8	927
SYT12	770
SYT11	-1089
CPNE9	-1319
DYSF	-5886

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ANXA1	7067
ANXA6	7019
CPNE1	6981
ESYT1	6579
C2CD5	6477
ANXA11	6474
CPNE2	6448
ANXA5	6410
ANXA13	5824
SYT17	5427
ANXA2	5074
ANXA7	3561
ESYT2	3293
CPNE3	3022
SYT13	2523
CPNE8	927
SYT12	770
SYT11	-1089
CPNE9	-1319
DYSF	-5886
PLA2G4A	-6150

---

GO:0007042 lysosomal lumen acidification

set	GO:0007042 lysosomal lumen acidification
setSize	10
pANOVA	0.00947
s.dist	0.474
p.adjustANOVA	0.147

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CREG1	6712
ATP6AP2	6519
TMEM106B	6221
LAMP1	4452
TMEM9	4177
TMEM199	3883
PPT1	3513
CLN6	2943
LAMP2	1748
CLN5	-7102

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CREG1	6712
ATP6AP2	6519
TMEM106B	6221
LAMP1	4452
TMEM9	4177
TMEM199	3883
PPT1	3513
CLN6	2943
LAMP2	1748
CLN5	-7102

---

GO:0042474 middle ear morphogenesis

set	GO:0042474 middle ear morphogenesis
setSize	10
pANOVA	0.0095
s.dist	0.474
p.adjustANOVA	0.147

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGFR1	6864
NKX3-2	6590
OSR2	6349
RPL38	6299
INSIG1	6226
NAGLU	1781
INSIG2	1546
TSHZ1	762
PRRX1	638
OSR1	-4004

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGFR1	6864
NKX3-2	6590
OSR2	6349
RPL38	6299
INSIG1	6226
NAGLU	1781
INSIG2	1546
TSHZ1	762
PRRX1	638
OSR1	-4004

---

GO:0061749 forked DNA-dependent helicase activity

set	GO:0061749 forked DNA-dependent helicase activity
setSize	10
pANOVA	0.00986
s.dist	-0.471
p.adjustANOVA	0.148

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	-7261
BLM	-6809
CHD1	-6268
MCM3	-5916
MCM9	-5677
ERCC3	-4320
CHD7	-4166
MCM8	-1095
MCM5	1865
WRN	4696

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	-7261
BLM	-6809
CHD1	-6268
MCM3	-5916
MCM9	-5677
ERCC3	-4320
CHD7	-4166
MCM8	-1095
MCM5	1865
WRN	4696

---

GO:0060216 definitive hemopoiesis

set	GO:0060216 definitive hemopoiesis
setSize	10
pANOVA	0.0116
s.dist	0.461
p.adjustANOVA	0.163

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HOXB4	6685
MFAP5	6544
ZFP36L2	6237
CBFB	5295
GATA2	5061
SP3	4817
MEIS1	2861
KMT2A	2009
BCR	-3108
HOXB3	-4266

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HOXB4	6685
MFAP5	6544
ZFP36L2	6237
CBFB	5295
GATA2	5061
SP3	4817
MEIS1	2861
KMT2A	2009
BCR	-3108
HOXB3	-4266

---

GO:0001819 positive regulation of cytokine production

set	GO:0001819 positive regulation of cytokine production
setSize	13
pANOVA	0.00438
s.dist	0.456
p.adjustANOVA	0.101

Top enriched genes

Top 20 genes

GeneID	Gene Rank
C1QTNF3	7021
CADM1	6862
AGPAT2	6185
TMF1	6014
SCAMP5	4631
KAT2A	4385
PELI3	2446
LURAP1	2259
PLA2R1	2189
SOD1	2024
IL18	-821
CD14	-924
HHLA2	-927

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
C1QTNF3	7021
CADM1	6862
AGPAT2	6185
TMF1	6014
SCAMP5	4631
KAT2A	4385
PELI3	2446
LURAP1	2259
PLA2R1	2189
SOD1	2024
IL18	-821
CD14	-924
HHLA2	-927

---

GO:0070034 telomerase RNA binding

set	GO:0070034 telomerase RNA binding
setSize	12
pANOVA	0.00627
s.dist	-0.456
p.adjustANOVA	0.122

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SMG6	-6999
SMG7	-6981
SMG5	-6680
DKC1	-6555
NAF1	-5883
EXOSC10	-4955
GAR1	-4923
XRN1	-2891
HNRNPU	-1262
PINX1	-969
DHX36	1626
PARN	5884

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SMG6	-6999
SMG7	-6981
SMG5	-6680
DKC1	-6555
NAF1	-5883
EXOSC10	-4955
GAR1	-4923
XRN1	-2891
HNRNPU	-1262
PINX1	-969
DHX36	1626
PARN	5884

---

GO:0090110 COPII-coated vesicle cargo loading

set	GO:0090110 COPII-coated vesicle cargo loading
setSize	10
pANOVA	0.0145
s.dist	0.447
p.adjustANOVA	0.183

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SEC24D	6970
SEC31A	6526
SURF4	6080
SEC13	5919
SEC23A	5401
SAR1B	4076
SEC24B	3007
SEC24A	1591
TBC1D20	-2514
SEC31B	-5960

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SEC24D	6970
SEC31A	6526
SURF4	6080
SEC13	5919
SEC23A	5401
SAR1B	4076
SEC24B	3007
SEC24A	1591
TBC1D20	-2514
SEC31B	-5960

---

GO:0070182 DNA polymerase binding

set	GO:0070182 DNA polymerase binding
setSize	13
pANOVA	0.00541
s.dist	-0.446
p.adjustANOVA	0.114

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HSP90AA1	-7185
FANCI	-7002
SMG6	-6999
NAT10	-6864
RTEL1	-6392
FANCD2	-5630
SMARCA4	-5387
NABP2	-5364
PTGES3	-1790
LONP1	-1082
NHEJ1	1822
PCNA	4077
POLG2	4774

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HSP90AA1	-7185
FANCI	-7002
SMG6	-6999
NAT10	-6864
RTEL1	-6392
FANCD2	-5630
SMARCA4	-5387
NABP2	-5364
PTGES3	-1790
LONP1	-1082
NHEJ1	1822
PCNA	4077
POLG2	4774

---

GO:0012506 vesicle membrane

set	GO:0012506 vesicle membrane
setSize	15
pANOVA	0.0034
s.dist	0.437
p.adjustANOVA	0.091

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ANXA1	7067
ANXA6	7019
ANXA11	6474
ANXA5	6410
ASPSCR1	6096
ANXA13	5824
GRB2	5725
ANXA2	5074
ANXA7	3561
DGKQ	875
TRAF2	-345
GIPC1	-362
FNDC3A	-1057
NCK1	-2172
PIKFYVE	-4601

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ANXA1	7067
ANXA6	7019
ANXA11	6474
ANXA5	6410
ASPSCR1	6096
ANXA13	5824
GRB2	5725
ANXA2	5074
ANXA7	3561
DGKQ	875
TRAF2	-345
GIPC1	-362
FNDC3A	-1057
NCK1	-2172
PIKFYVE	-4601

---

GO:0000245 spliceosomal complex assembly

set	GO:0000245 spliceosomal complex assembly
setSize	10
pANOVA	0.0169
s.dist	-0.436
p.adjustANOVA	0.192

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SCAF11	-6705
SRPK2	-5825
SRPK1	-5268
SF3B1	-5148
RBM10	-4392
PRPF19	-2817
ZRSR2	-1821
USP39	-1680
SF3A2	139
RSRP1	1100

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SCAF11	-6705
SRPK2	-5825
SRPK1	-5268
SF3B1	-5148
RBM10	-4392
PRPF19	-2817
ZRSR2	-1821
USP39	-1680
SF3A2	139
RSRP1	1100

---

GO:0030020 extracellular matrix structural constituent conferring tensile strength

set	GO:0030020 extracellular matrix structural constituent conferring tensile strength
setSize	17
pANOVA	0.00193
s.dist	0.434
p.adjustANOVA	0.0609

Top enriched genes

Top 20 genes

GeneID	Gene Rank
COL8A1	7097
COL18A1	7068
COL5A2	7057
COL11A1	7034
COL1A1	6889
COL3A1	6861
COL16A1	6612
COL1A2	6430
COL5A1	6171
COL6A1	5614
COLQ	2867
COL9A2	-181
COL17A1	-1225
EMID1	-1999
COL4A2	-3381
COL4A6	-5099
COL26A1	-6450

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
COL8A1	7097
COL18A1	7068
COL5A2	7057
COL11A1	7034
COL1A1	6889
COL3A1	6861
COL16A1	6612
COL1A2	6430
COL5A1	6171
COL6A1	5614
COLQ	2867
COL9A2	-181
COL17A1	-1225
EMID1	-1999
COL4A2	-3381
COL4A6	-5099
COL26A1	-6450

---

GO:0030992 intraciliary transport particle B

set	GO:0030992 intraciliary transport particle B
setSize	15
pANOVA	0.00366
s.dist	0.433
p.adjustANOVA	0.091

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TRIM59	6784
IFT27	6376
HSPB11	6287
IFT46	6141
IFT52	6059
IFT81	4315
TRAF3IP1	4254
IFT88	4197
IFT172	3483
IFT80	3196
IFT74	2053
IFT20	366
IFT22	-1142
IFT57	-3530
UBXN10	-3620

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TRIM59	6784
IFT27	6376
HSPB11	6287
IFT46	6141
IFT52	6059
IFT81	4315
TRAF3IP1	4254
IFT88	4197
IFT172	3483
IFT80	3196
IFT74	2053
IFT20	366
IFT22	-1142
IFT57	-3530
UBXN10	-3620

---

GO:0009888 tissue development

set	GO:0009888 tissue development
setSize	18
pANOVA	0.00157
s.dist	-0.43
p.adjustANOVA	0.0544

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NTN4	-7197
DHCR24	-6930
POSTN	-6852
LAMC2	-6531
NTNG2	-6131
ACVR1B	-5926
LAMB1	-5704
LAMA3	-4050
NTN3	-4038
USH2A	-1936
ACVR1C	-1757
SMO	-1418
LAMA5	-1413
LAMB3	-1093
LAMC1	-918
GAA	-454
LAMA2	195
LAMB2	4564

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NTN4	-7197
DHCR24	-6930
POSTN	-6852
LAMC2	-6531
NTNG2	-6131
ACVR1B	-5926
LAMB1	-5704
LAMA3	-4050
NTN3	-4038
USH2A	-1936
ACVR1C	-1757
SMO	-1418
LAMA5	-1413
LAMB3	-1093
LAMC1	-918
GAA	-454
LAMA2	195
LAMB2	4564

---

GO:0007099 centriole replication

set	GO:0007099 centriole replication
setSize	13
pANOVA	0.00789
s.dist	0.426
p.adjustANOVA	0.137

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CETN2	6005
KIAA0753	5744
CEP44	5326
CCP110	5115
SASS6	4795
CEP135	4232
CDK2	3647
POC1B	3601
CEP63	3332
RTTN	1239
PLK4	766
CEP85	388
CDK5RAP2	-5733

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CETN2	6005
KIAA0753	5744
CEP44	5326
CCP110	5115
SASS6	4795
CEP135	4232
CDK2	3647
POC1B	3601
CEP63	3332
RTTN	1239
PLK4	766
CEP85	388
CDK5RAP2	-5733

---

GO:0006412 translation

set	GO:0006412 translation
setSize	96
pANOVA	6.35e-13
s.dist	0.425
p.adjustANOVA	3.74e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS15A	7077
RPL13	7069
RPS2	7055
RPS4Y1	6998
RPS3A	6989
GSPT2	6986
RPL35	6982
RPL3	6968
RPS7	6860
RPS3	6841
RPS20	6837
RPS15	6804
RPL37	6798
RPS14	6779
RPL14	6726
RPL27A	6708
RPS13	6687
RPL34	6677
RPL26L1	6669
RPS21	6631

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS15A	7077
RPL13	7069
RPS2	7055
RPS4Y1	6998
RPS3A	6989
GSPT2	6986
RPL35	6982
RPL3	6968
RPS7	6860
RPS3	6841
RPS20	6837
RPS15	6804
RPL37	6798
RPS14	6779
RPL14	6726
RPL27A	6708
RPS13	6687
RPL34	6677
RPL26L1	6669
RPS21	6631
RPL27	6627
RPL32	6549
RPL11	6521
RPS23	6499
RPL5	6494
RPS27A	6472
RPL37A	6449
RPS8	6219
RPL22	6069
RPS24	6010
MRPS18A	5877
RPS16	5874
RPS11	5830
RPL35A	5806
MRPL51	5613
GUF1	5585
MRPS17	5509
RPL23A	5487
MRPL37	5243
RPL23	5046
MRPL14	5041
RPS17	4996
MRPL35	4971
MRPL13	4938
MRPS21	4924
RPL21	4780
MRPL24	4759
MRPL32	4625
RPL22L1	4343
RPL12	4336
RPL19	4230
RPL3L	3915
MRPS23	3858
MRPL36	3731
MRPS6	3708
SRBD1	3464
RPS29	3463
UBA52	2851
MRPL41	2725
MRPL16	2640
MRPS12	1866
EIF2AK2	1824
TRNAU1AP	1599
CPEB3	1520
MRPL2	1147
MRPS5	1139
MRPL12	1132
MRPS16	1115
CPEB4	1031
C2H6orf52	746
MRPL17	736
MRPS18C	541
MRPL18	209
MRPL19	-116
MRPS9	-291
MRPS30	-1212
DDA1	-1421
MRPL22	-1455
RPS27L	-1653
MRPL33	-1859
MRPL49	-2076
MRPL27	-2082
MRPL47	-2421
MRPL15	-2670
MRPL20	-2997
MRPS15	-3274
EIF4ENIF1	-3278
RPL4	-3483
MRPL3	-3897
MRPS14	-4706
MRPS10	-5167
MRPS11	-5388
MRPS7	-5430
MRPS2	-5503
HBS1L	-5660
MRPL10	-5940

---

GO:0004364 glutathione transferase activity

set	GO:0004364 glutathione transferase activity
setSize	10
pANOVA	0.0204
s.dist	0.423
p.adjustANOVA	0.221

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HPGDS	6941
GSTO2	6727
MGST1	5651
MGST3	5458
GSTM2	5445
GSTT1	4896
GSTK1	982
PTGES	-119
GSTZ1	-1000
LANCL1	-5541

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HPGDS	6941
GSTO2	6727
MGST1	5651
MGST3	5458
GSTM2	5445
GSTT1	4896
GSTK1	982
PTGES	-119
GSTZ1	-1000
LANCL1	-5541

---

GO:0141198 protein branched polyubiquitination

set	GO:0141198 protein branched polyubiquitination
setSize	13
pANOVA	0.00857
s.dist	-0.421
p.adjustANOVA	0.14

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ANAPC1	-6214
ANAPC16	-6198
ANAPC7	-5958
CDC23	-5626
CDC27	-5472
CDC16	-4367
UBR4	-3492
ANAPC4	-2964
UBR5	-2479
ANAPC5	-2242
CDC26	-1192
ANAPC2	511
ITCH	4959

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ANAPC1	-6214
ANAPC16	-6198
ANAPC7	-5958
CDC23	-5626
CDC27	-5472
CDC16	-4367
UBR4	-3492
ANAPC4	-2964
UBR5	-2479
ANAPC5	-2242
CDC26	-1192
ANAPC2	511
ITCH	4959

---

GO:0005791 rough endoplasmic reticulum

set	GO:0005791 rough endoplasmic reticulum
setSize	12
pANOVA	0.0119
s.dist	-0.419
p.adjustANOVA	0.163

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PKLR	-7086
CDKAL1	-5300
SUCO	-5286
SPPL3	-4676
PLOD2	-4525
PSEN1	-4473
LRAT	-4252
TMCC1	-4085
RPL4	-3483
MYOC	-1098
HM13	205
RPL27	6627

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PKLR	-7086
CDKAL1	-5300
SUCO	-5286
SPPL3	-4676
PLOD2	-4525
PSEN1	-4473
LRAT	-4252
TMCC1	-4085
RPL4	-3483
MYOC	-1098
HM13	205
RPL27	6627

---

GO:0000774 adenyl-nucleotide exchange factor activity

set	GO:0000774 adenyl-nucleotide exchange factor activity
setSize	12
pANOVA	0.012
s.dist	-0.419
p.adjustANOVA	0.163

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BAG3	-7077
HSPH1	-6761
HSPA4	-6719
HYOU1	-6487
HSPA4L	-5009
BAG2	-4734
SIL1	-3839
GRPEL1	-3465
BAG1	-2952
BAG5	-601
BAG4	3638
GRPEL2	6594

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BAG3	-7077
HSPH1	-6761
HSPA4	-6719
HYOU1	-6487
HSPA4L	-5009
BAG2	-4734
SIL1	-3839
GRPEL1	-3465
BAG1	-2952
BAG5	-601
BAG4	3638
GRPEL2	6594

---

GO:0051642 centrosome localization

set	GO:0051642 centrosome localization
setSize	14
pANOVA	0.0067
s.dist	0.419
p.adjustANOVA	0.129

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SUN1	7031
DLGAP5	6792
CCDC141	6718
SUN2	6374
NUBP1	6264
NDE1	5282
NIN	5253
PLXNA2	2959
BICD2	1405
NDEL1	1105
IFT20	366
KIF5B	-1424
INTS13	-3493
SYNE2	-3926

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SUN1	7031
DLGAP5	6792
CCDC141	6718
SUN2	6374
NUBP1	6264
NDE1	5282
NIN	5253
PLXNA2	2959
BICD2	1405
NDEL1	1105
IFT20	366
KIF5B	-1424
INTS13	-3493
SYNE2	-3926

---

GO:0070507 regulation of microtubule cytoskeleton organization

set	GO:0070507 regulation of microtubule cytoskeleton organization
setSize	14
pANOVA	0.00698
s.dist	0.416
p.adjustANOVA	0.129

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KIF18A	6441
PHLDB2	6421
PAFAH1B1	5992
CDK2AP2	5988
EFNA5	4268
TRAF3IP1	4254
CYLD	3158
TRIM36	3151
DIXDC1	2474
BICD2	1405
CEP70	443
PRKAA1	190
ROCK1	-697
MID1	-2990

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KIF18A	6441
PHLDB2	6421
PAFAH1B1	5992
CDK2AP2	5988
EFNA5	4268
TRAF3IP1	4254
CYLD	3158
TRIM36	3151
DIXDC1	2474
BICD2	1405
CEP70	443
PRKAA1	190
ROCK1	-697
MID1	-2990

---

GO:0045292 mRNA cis splicing, via spliceosome

set	GO:0045292 mRNA cis splicing, via spliceosome
setSize	13
pANOVA	0.00967
s.dist	-0.415
p.adjustANOVA	0.147

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SRSF3	-6775
CACTIN	-6283
CWC15	-5812
RBM22	-5224
SF3A1	-5188
PRPF40A	-5036
RBM17	-4698
SRSF7L	-4510
CLNS1A	-3782
NCBP2	-2707
SDE2	-673
DCPS	5134
WBP4	5440

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SRSF3	-6775
CACTIN	-6283
CWC15	-5812
RBM22	-5224
SF3A1	-5188
PRPF40A	-5036
RBM17	-4698
SRSF7L	-4510
CLNS1A	-3782
NCBP2	-2707
SDE2	-673
DCPS	5134
WBP4	5440

---

GO:0010971 positive regulation of G2/M transition of mitotic cell cycle

set	GO:0010971 positive regulation of G2/M transition of mitotic cell cycle
setSize	14
pANOVA	0.0075
s.dist	-0.413
p.adjustANOVA	0.133

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SIN3A	-6890
RRM1	-6469
RRM2B	-5972
RAB11A	-5444
VPS4B	-5247
CCND1	-5182
CDC25A	-5045
DTL	-2998
CDC7	-1698
CDK1	-1078
FBXO5	-860
RCC2	-808
HSPA2	1022
RAD51B	3646

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SIN3A	-6890
RRM1	-6469
RRM2B	-5972
RAB11A	-5444
VPS4B	-5247
CCND1	-5182
CDC25A	-5045
DTL	-2998
CDC7	-1698
CDK1	-1078
FBXO5	-860
RCC2	-808
HSPA2	1022
RAD51B	3646

---

GO:0032924 activin receptor signaling pathway

set	GO:0032924 activin receptor signaling pathway
setSize	12
pANOVA	0.0143
s.dist	-0.408
p.adjustANOVA	0.182

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SMAD3	-7228
TGFBR2	-6800
ACVR2A	-6604
INHBA	-6326
BMPR1A	-5130
BMPR2	-2105
ACVR2B	-1974
ACVR1C	-1757
ATVR1	-1384
GDF11	-1039
INHBB	1314
SMAD2	2528

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SMAD3	-7228
TGFBR2	-6800
ACVR2A	-6604
INHBA	-6326
BMPR1A	-5130
BMPR2	-2105
ACVR2B	-1974
ACVR1C	-1757
ATVR1	-1384
GDF11	-1039
INHBB	1314
SMAD2	2528

---

GO:0061775 cohesin loader activity

set	GO:0061775 cohesin loader activity
setSize	24
pANOVA	0.000536
s.dist	-0.408
p.adjustANOVA	0.0316

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	-7261
BLM	-6809
CHD1	-6268
SUPV3L1	-6106
MCM3	-5916
DDX6	-5874
DDX55	-5766
EIF4A2	-5736
MCM9	-5677
DDX42	-5526
DHX30	-5231
ERCC3	-4320
BRIP1	-4296
FANCM	-4283
CHD7	-4166
MAU2	-3456
DDX1	-2819
DNA2	-2811
MCM8	-1095
MOV10	2508

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	-7261
BLM	-6809
CHD1	-6268
SUPV3L1	-6106
MCM3	-5916
DDX6	-5874
DDX55	-5766
EIF4A2	-5736
MCM9	-5677
DDX42	-5526
DHX30	-5231
ERCC3	-4320
BRIP1	-4296
FANCM	-4283
CHD7	-4166
MAU2	-3456
DDX1	-2819
DNA2	-2811
MCM8	-1095
MOV10	2508
DDX10	2973
HSPA5	4190
PMS2	5079
EIF4A3	5731

---

GO:0140588 chromatin looping

set	GO:0140588 chromatin looping
setSize	27
pANOVA	0.000255
s.dist	-0.407
p.adjustANOVA	0.0206

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TWNK	-7261
PCBP2	-7118
BRD2	-7116
BLM	-6809
CHD1	-6268
SUPV3L1	-6106
MCM3	-5916
DDX6	-5874
DDX55	-5766
EIF4A2	-5736
MCM9	-5677
DDX42	-5526
DHX30	-5231
CTCF	-4648
ERCC3	-4320
BRIP1	-4296
FANCM	-4283
CHD7	-4166
DDX1	-2819
DNA2	-2811

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TWNK	-7261
PCBP2	-7118
BRD2	-7116
BLM	-6809
CHD1	-6268
SUPV3L1	-6106
MCM3	-5916
DDX6	-5874
DDX55	-5766
EIF4A2	-5736
MCM9	-5677
DDX42	-5526
DHX30	-5231
CTCF	-4648
ERCC3	-4320
BRIP1	-4296
FANCM	-4283
CHD7	-4166
DDX1	-2819
DNA2	-2811
MCM8	-1095
MOV10	2508
DDX10	2973
HSPA5	4190
PMS2	5079
EIF4A3	5731
RAD21	6654

---

GO:0048041 focal adhesion assembly

set	GO:0048041 focal adhesion assembly
setSize	14
pANOVA	0.0085
s.dist	-0.406
p.adjustANOVA	0.14

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FN1	-7207
PTPRK	-7027
PIP5K1A	-6696
PEAK1	-6080
CDH11	-4920
THY1	-4215
WHAMM	-4104
FERMT2	-3953
BCL2	-3721
BCR	-3108
SRC	-2034
RCC2	-808
CORO2B	4418
ARHGAP6	7089

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FN1	-7207
PTPRK	-7027
PIP5K1A	-6696
PEAK1	-6080
CDH11	-4920
THY1	-4215
WHAMM	-4104
FERMT2	-3953
BCL2	-3721
BCR	-3108
SRC	-2034
RCC2	-808
CORO2B	4418
ARHGAP6	7089

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.4.2 (2024-10-31)
## Platform: x86_64-pc-linux-gnu
## Running under: Ubuntu 24.04.1 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.12.0 
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.12.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Australia/Melbourne
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] stats4    stats     graphics  grDevices utils     datasets  methods  
## [8] base     
## 
## other attached packages:
##  [1] pkgload_1.4.0               GGally_2.2.1               
##  [3] ggplot2_3.5.1               gtools_3.9.5               
##  [5] tibble_3.2.1                echarts4r_0.4.5            
##  [7] UpSetR_1.4.0                beeswarm_0.4.0             
##  [9] kableExtra_1.4.0            eulerr_7.0.2               
## [11] mitch_1.19.2                MASS_7.3-61                
## [13] gplots_3.2.0                DESeq2_1.44.0              
## [15] SummarizedExperiment_1.34.0 Biobase_2.64.0             
## [17] MatrixGenerics_1.16.0       matrixStats_1.4.1          
## [19] GenomicRanges_1.56.1        GenomeInfoDb_1.40.1        
## [21] IRanges_2.38.1              S4Vectors_0.42.1           
## [23] BiocGenerics_0.50.0         reshape2_1.4.4             
## [25] dplyr_1.1.4                 zoo_1.8-12                 
## 
## loaded via a namespace (and not attached):
##  [1] tidyselect_1.2.1        viridisLite_0.4.2       farver_2.1.2           
##  [4] bitops_1.0-9            fastmap_1.2.0           promises_1.3.2         
##  [7] digest_0.6.37           mime_0.12               lifecycle_1.0.4        
## [10] polylabelr_0.3.0        magrittr_2.0.3          compiler_4.4.2         
## [13] rlang_1.1.4             sass_0.4.9              tools_4.4.2            
## [16] yaml_2.3.10             knitr_1.49              labeling_0.4.3         
## [19] S4Arrays_1.4.1          htmlwidgets_1.6.4       DelayedArray_0.30.1    
## [22] xml2_1.3.6              plyr_1.8.9              RColorBrewer_1.1-3     
## [25] abind_1.4-8             BiocParallel_1.38.0     KernSmooth_2.23-24     
## [28] withr_3.0.2             purrr_1.0.2             polyclip_1.10-7        
## [31] grid_4.4.2              caTools_1.18.3          xtable_1.8-4           
## [34] colorspace_2.1-1        scales_1.3.0            cli_3.6.3              
## [37] rmarkdown_2.29          crayon_1.5.3            generics_0.1.3         
## [40] rstudioapi_0.17.1       httr_1.4.7              cachem_1.1.0           
## [43] stringr_1.5.1           zlibbioc_1.50.0         parallel_4.4.2         
## [46] XVector_0.44.0          vctrs_0.6.5             Matrix_1.7-1           
## [49] jsonlite_1.8.9          systemfonts_1.1.0       locfit_1.5-9.10        
## [52] jquerylib_0.1.4         tidyr_1.3.1             glue_1.8.0             
## [55] ggstats_0.7.0           codetools_0.2-20        stringi_1.8.4          
## [58] gtable_0.3.6            later_1.4.1             UCSC.utils_1.0.0       
## [61] munsell_0.5.1           pillar_1.10.0           htmltools_0.5.8.1      
## [64] GenomeInfoDbData_1.2.12 R6_2.5.1                evaluate_1.0.1         
## [67] shiny_1.10.0            lattice_0.22-6          httpuv_1.6.15          
## [70] bslib_0.8.0             Rcpp_1.0.13-1           svglite_2.1.3          
## [73] gridExtra_2.3           SparseArray_1.4.8       xfun_0.49              
## [76] pkgconfig_2.0.3

END of report