Source: https://github.com/markziemann/GeneNameErrors2020

View the reports: http://ziemann-lab.net/public/gene_name_errors/

Intro

Gene name errors result when data are imported improperly into MS Excel and other spreadsheet programs (Zeeberg et al, 2004). Certain gene names like MARCH3, SEPT2 and DEC1 are converted into date format. These errors are surprisingly common in supplementary data files in the field of genomics (Ziemann et al, 2016). This could be considered a small error because it only affects a small number of genes, however it is symptomtic of poor data processing methods. The purpose of this script is to identify gene name errors present in supplementary files of PubMed Central articles in the previous month.

library("XML")
library("jsonlite")
library("xml2")
library("reutils")
library("readxl")

Get PMC IDs

Here I will be getting PubMed Central IDs for the previous month.

Start with figuring out the date to search PubMed Central.

CURRENT_MONTH=format(Sys.time(), "%m")
CURRENT_YEAR=format(Sys.time(), "%Y")

if (CURRENT_MONTH == "01") {
  PREV_YEAR=as.character(as.numeric(format(Sys.time(), "%Y"))-1)
  PREV_MONTH="12"
} else {
  PREV_YEAR=CURRENT_YEAR
  PREV_MONTH=as.character(as.numeric(format(Sys.time(), "%m"))-1)
}

DATE=paste(PREV_YEAR,"/",PREV_MONTH,sep="")
DATE
## [1] "2022/3"

Let’s see how many PMC IDs we have in the past month.

QUERY ='((genom*[Abstract]))'

ESEARCH_RES <- esearch(term=QUERY, db = "pmc", rettype = "uilist", retmode = "xml", retstart = 0, 
  retmax = 5000000, usehistory = TRUE, webenv = NULL, querykey = NULL, sort = NULL, field = NULL, 
  datetype = NULL, reldate = NULL, mindate = DATE, maxdate = DATE)

pmc <- efetch(ESEARCH_RES,retmode="text",rettype="uilist",outfile="pmcids.txt")
## Retrieving UIDs 1 to 500
## Retrieving UIDs 501 to 1000
## Retrieving UIDs 1001 to 1500
## Retrieving UIDs 1501 to 2000
## Retrieving UIDs 2001 to 2500
## Retrieving UIDs 2501 to 3000
## Retrieving UIDs 3001 to 3500
pmc <- read.table(pmc)
pmc <- paste("PMC",pmc$V1,sep="")
NUM_ARTICLES=length(pmc)
NUM_ARTICLES
## [1] 3310
writeLines(pmc,con="pmc.txt")

Run the screen

Now run the bash script. Note that false positives can occur (~1.5%) and these results have not been verified by a human.

Here are some definitions:

system("./gene_names.sh pmc.txt")
results <- readLines("results.txt")

XLS <- results[grep("XLS",results,ignore.case=TRUE)]
NUM_XLS = length(XLS)
NUM_XLS
## [1] 4644
NUM_XLS_ARTICLES = length(unique(sapply(strsplit(XLS," "),"[[",1)))
NUM_XLS_ARTICLES
## [1] 768
GENELISTS <- XLS[lapply(strsplit(XLS," "),length)>2]
#GENELISTS

NUM_GENELISTS <- length(unique(sapply(strsplit(GENELISTS," "),"[[",2)))
NUM_GENELISTS
## [1] 582
NUM_GENELIST_ARTICLES <- length(unique(sapply(strsplit(GENELISTS," "),"[[",1)))
NUM_GENELIST_ARTICLES
## [1] 276
ERROR_GENELISTS <- XLS[lapply(strsplit(XLS," "),length)>3]
#ERROR_GENELISTS

NUM_ERROR_GENELISTS = length(ERROR_GENELISTS)
NUM_ERROR_GENELISTS
## [1] 211
GENELIST_ERROR_ARTICLES <- unique(sapply(strsplit(ERROR_GENELISTS," "),"[[",1))
GENELIST_ERROR_ARTICLES
##  [1] "PMC8960258" "PMC8958792" "PMC8958363" "PMC8941526" "PMC8938417"
##  [6] "PMC8957956" "PMC8947600" "PMC8941758" "PMC8940286" "PMC8938861"
## [11] "PMC8937020" "PMC8925074" "PMC8903709" "PMC8934046" "PMC8931337"
## [16] "PMC8930846" "PMC8883549" "PMC8883538" "PMC8930202" "PMC8927907"
## [21] "PMC8927698" "PMC8891275" "PMC8885711" "PMC8881579" "PMC8863982"
## [26] "PMC8923467" "PMC8921613" "PMC8919059" "PMC8912178" "PMC8892733"
## [31] "PMC8896830" "PMC8831532" "PMC8888678" "PMC8885993" "PMC8884250"
## [36] "PMC8967178" "PMC8966188" "PMC8960263" "PMC8959321" "PMC8942222"
## [41] "PMC8904843" "PMC8916121" "PMC8891017" "PMC8933692" "PMC8931336"
## [46] "PMC8925295" "PMC8924366" "PMC8921511" "PMC8921118" "PMC8888590"
## [51] "PMC8885418" "PMC8873204" "PMC8864016" "PMC8861042" "PMC8923497"
## [56] "PMC8921988" "PMC8915965" "PMC8913945" "PMC8907571" "PMC8891552"
## [61] "PMC8905247" "PMC8902468" "PMC8896005" "PMC8894600" "PMC8892324"
## [66] "PMC8891516" "PMC8889144" "PMC8844066" "PMC8837555" "PMC8887668"
## [71] "PMC8885996" "PMC8884696"
NUM_ERROR_GENELIST_ARTICLES <- length(GENELIST_ERROR_ARTICLES) 
NUM_ERROR_GENELIST_ARTICLES
## [1] 72
ERROR_PROPORTION = NUM_ERROR_GENELIST_ARTICLES / NUM_GENELIST_ARTICLES
ERROR_PROPORTION
## [1] 0.2608696

Look at the errors detected

Here you can have a look at all the gene lists detected in the past month, as well as those with errors. The dates are obvious errors, these are commonly dates in September, March, December and October. The five-digit numbers represent dates as they are encoded in the Excel internal format. The five digit number is the number of days since 1900. If you were to take these numbers and put them into Excel and format the cells as dates, then these will also mostly map to dates in September, March, December and October.

#GENELISTS

ERROR_GENELISTS
##   [1] "PMC8960258 /pmc/articles/PMC8960258/bin/Table5.XLSX Hsapiens 2 44263 44448"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
##   [2] "PMC8958792 /pmc/articles/PMC8958792/bin/13148_2022_1267_MOESM2_ESM.xlsx Rnorvegicus 16 44441 44262 44450 44263 44440 44256 44447 44265 44448 44448 44266 44266 44266 44442 44258 44445"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
##   [3] "PMC8958792 /pmc/articles/PMC8958792/bin/13148_2022_1267_MOESM2_ESM.xlsx Rnorvegicus 17 44259 44256 44257 44257 44450 44453 44256 44256 44265 44265 44265 44448 44448 44448 44266 44266 44266"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
##   [4] "PMC8958792 /pmc/articles/PMC8958792/bin/13148_2022_1267_MOESM2_ESM.xlsx Rnorvegicus 28 44259 44259 44256 44257 44257 44262 44262 44450 44440 44256 44256 44256 44446 44443 44265 44448 44448 44266 44266 44266 44261 44444 44258 44258 44258 44258 44258 44445"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
##   [5] "PMC8958792 /pmc/articles/PMC8958792/bin/13148_2022_1267_MOESM2_ESM.xlsx Mmusculus 37 44256 44257 44257 44453 44453 44263 44256 44256 44449 44264 44447 44265 44265 44265 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44266 44266 44266 44266 44261 44451 44444 44444 44258 44258 44258 44445 44445"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
##   [6] "PMC8958792 /pmc/articles/PMC8958792/bin/13148_2022_1267_MOESM2_ESM.xlsx Rnorvegicus 45 44256 44257 44257 44450 44450 44450 44450 44450 44263 44440 44446 44447 44443 44443 44265 44265 44265 44265 44265 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44266 44266 44266 44266 44444 44444 44258 44258 44258 44445"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
##   [7] "PMC8958792 /pmc/articles/PMC8958792/bin/13148_2022_1267_MOESM3_ESM.xlsx Mmusculus 2 44450 44443"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
##   [8] "PMC8958792 /pmc/articles/PMC8958792/bin/13148_2022_1267_MOESM3_ESM.xlsx Mmusculus 6 44440 44449 44450 44441 44445 44447"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
##   [9] "PMC8958363 /pmc/articles/PMC8958363/bin/mmc2.xlsx Mmusculus 4 43899 43896 44088 44083"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
##  [10] "PMC8958363 /pmc/articles/PMC8958363/bin/mmc2.xlsx Mmusculus 1 43896"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
##  [11] "PMC8958363 /pmc/articles/PMC8958363/bin/mmc3.xlsx Mmusculus 21 43894 43899 43901 44081 44083 43896 44077 44078 43893 43892 43891 43897 44084 44085 44086 43895 44088 43900 44082 44075 43892"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
##  [12] "PMC8958363 /pmc/articles/PMC8958363/bin/mmc3.xlsx Mmusculus 21 43894 43899 43901 44081 44083 43896 44077 44078 43893 43892 43891 43897 44084 44085 44086 43895 44088 43900 44082 44075 43892"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
##  [13] "PMC8958363 /pmc/articles/PMC8958363/bin/mmc3.xlsx Mmusculus 21 43894 43899 43901 44081 44083 43896 44077 44078 43893 43892 43891 43897 44084 44085 44086 43895 44088 43900 44082 44075 43892"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
##  [14] "PMC8958363 /pmc/articles/PMC8958363/bin/mmc3.xlsx Mmusculus 21 43894 43899 43901 44081 44083 43896 44077 44078 43893 43892 43891 43897 44084 44085 44086 43895 44088 43900 44082 44075 43892"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
##  [15] "PMC8941526 /pmc/articles/PMC8941526/bin/Supplementary_Data2.xlsx Hsapiens 2 44450 44441"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
##  [16] "PMC8938417 /pmc/articles/PMC8938417/bin/41598_2022_8645_MOESM3_ESM.xlsx Hsapiens 2 40057 38961"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
##  [17] "PMC8957956 /pmc/articles/PMC8957956/bin/Table_1.xlsx Hsapiens 332 43352 43164 43345 43353 43350 43352 43350 43354 43165 43354 43345 43163 43345 43353 43168 43166 43350 43165 43352 43345 43168 43353 43352 43165 43349 43345 43349 43345 43354 43160 43345 43166 43349 43161 43345 43345 43351 43345 43350 43166 43345 43352 43161 43345 43350 43350 43349 43353 43345 43352 43345 43353 43352 43352 43351 43351 43345 43354 43350 43351 43353 43164 43345 43354 43345 43167 43166 43344 43353 43345 43345 43345 43165 43345 43354 43345 43161 43350 43350 43161 43165 43349 43345 43345 43161 43345 43353 43351 43345 43161 43350 43345 43345 43349 43162 43165 43345 43354 43345 43352 43352 43352 43161 43353 43352 43167 43165 43345 43165 43351 43353 43352 43166 43352 43345 43345 43352 43350 43166 43352 43165 43352 43351 43345 43348 43348 43352 43165 43353 43168 43167 43352 43351 43350 43352 43354 43345 43166 43352 43349 43169 43352 43344 43344 43348 43352 43353 43352 43352 43167 43354 43160 43348 43353 43351 43169 43354 43167 43160 43351 43348 43348 43347 43164 43352 43345 43345 43352 43160 43345 43350 43354 43167 43160 43351 43169 43160 43355 43348 43351 43347 43165 43164 43160 43165 43351 43169 43352 43166 43352 43346 43347 43347 43350 43165 43160 43352 43352 43350 43161 43161 43161 43161 43161 43161 43160 43160 43160 43160 43160 43160 43160 43167 43355 43355 43355 43355 43355 43355 43355 43344 43344 43344 43344 43344 43344 43344 43347 43347 43347 43347 43347 43347 43347 43347 43347 43347 43347 43347 43347 43347 43347 43347 43347 43347 43347 43347 43347 43347 43347 43347 43347 43169 43169 43169 43169 43169 43169 43352 43352 43352 43352 43352 43352 43352 43352 43352 43352 43352 43352 43352 43352 43352 43352 43161 43353 43166 43345 43345 43345 43345 43345 43345 43345 43348 43348 43348 43348 43348 43348 43346 43346 43346 43346 43346 43346 43354 43354 43354 43354 43354 43160 43160 43160 43160 43160 43160 43160 43165 43165 43170 43170 43170 43162 43162 43162 43162 43351 43351 43351 43350 43350 43350 43350 43357 43357 43435 43435 43435 43435 43349 43349"
##  [18] "PMC8947600 /pmc/articles/PMC8947600/bin/pcbi.1009395.s002.xlsx Hsapiens 4 10423 10423 11219 11219"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
##  [19] "PMC8947600 /pmc/articles/PMC8947600/bin/pcbi.1009395.s002.xlsx Ggallus 6 55276 55276 26289 26289 26289 26289"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
##  [20] "PMC8947600 /pmc/articles/PMC8947600/bin/pcbi.1009395.s002.xlsx Hsapiens 3 64078 64078 55276"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
##  [21] "PMC8947600 /pmc/articles/PMC8947600/bin/pcbi.1009395.s003.xlsx Hsapiens 9 10587 10587 10587 10587 11219 11219 11219 10514 10555"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
##  [22] "PMC8941758 /pmc/articles/PMC8941758/bin/12915_2022_1270_MOESM10_ESM.xlsx Hsapiens 25 37226 36951 37316 36951 40238 40603 37316 37681 38047 38412 38777 39142 39508 39873 37135 40422 40787 37500 37865 38231 38596 38961 39326 39692 40057"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
##  [23] "PMC8941758 /pmc/articles/PMC8941758/bin/12915_2022_1270_MOESM10_ESM.xlsx Mmusculus 26 36951 37316 36951 40238 40603 37316 37681 38047 38412 38777 39142 39508 39873 37135 40422 40787 41153 41883 37500 37865 38231 38596 38961 39326 39692 40057"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
##  [24] "PMC8941758 /pmc/articles/PMC8941758/bin/12915_2022_1270_MOESM10_ESM.xlsx Hsapiens 26 36951 37316 36951 40238 40603 37316 37681 38047 38412 38777 39142 39508 39873 37135 40422 40787 41153 41883 37500 37865 38231 38596 38961 39326 39692 40057"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
##  [25] "PMC8941758 /pmc/articles/PMC8941758/bin/12915_2022_1270_MOESM10_ESM.xlsx Hsapiens 23 36951 37316 36951 40238 40603 37316 37681 38047 38412 38777 39142 39508 39873 37135 40422 40787 41883 37865 38231 38961 39326 39692 40057"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
##  [26] "PMC8941758 /pmc/articles/PMC8941758/bin/12915_2022_1270_MOESM10_ESM.xlsx Hsapiens 20 36951 36951 40603 37316 37681 38047 38412 38777 39142 39508 40422 40787 41153 37500 38231 38596 38961 39326 39692 40057"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
##  [27] "PMC8940286 /pmc/articles/PMC8940286/bin/Table_7.xlsx Hsapiens 1 39142"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
##  [28] "PMC8940286 /pmc/articles/PMC8940286/bin/Table_7.xlsx Hsapiens 1 38412"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
##  [29] "PMC8940286 /pmc/articles/PMC8940286/bin/Table_7.xlsx Hsapiens 1 38412"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
##  [30] "PMC8940286 /pmc/articles/PMC8940286/bin/Table_7.xlsx Hsapiens 1 37500"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
##  [31] "PMC8940286 /pmc/articles/PMC8940286/bin/Table_7.xlsx Ggallus 2 39692 39326"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
##  [32] "PMC8940286 /pmc/articles/PMC8940286/bin/Table_7.xlsx Hsapiens 2 38777 39326"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
##  [33] "PMC8940286 /pmc/articles/PMC8940286/bin/Table_7.xlsx Hsapiens 1 36951"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
##  [34] "PMC8940286 /pmc/articles/PMC8940286/bin/Table_7.xlsx Hsapiens 1 40422"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
##  [35] "PMC8940286 /pmc/articles/PMC8940286/bin/Table_7.xlsx Hsapiens 1 38961"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
##  [36] "PMC8938861 /pmc/articles/PMC8938861/bin/mmc3.xlsx Hsapiens 1 44411"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
##  [37] "PMC8938861 /pmc/articles/PMC8938861/bin/mmc6.xlsx Hsapiens 7 44452 44448 44448 44448 44448 44448 44450"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
##  [38] "PMC8938861 /pmc/articles/PMC8938861/bin/mmc8.xlsx Hsapiens 2 44444 44444"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
##  [39] "PMC8938861 /pmc/articles/PMC8938861/bin/mmc8.xlsx Hsapiens 7 44445 44444 44448 44448 44448 44444 44444"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
##  [40] "PMC8938861 /pmc/articles/PMC8938861/bin/mmc9.xlsx Hsapiens 5 44440 44454 44410 44448 44409"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
##  [41] "PMC8938861 /pmc/articles/PMC8938861/bin/mmc9.xlsx Hsapiens 3 44452 44448 44444"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
##  [42] "PMC8938861 /pmc/articles/PMC8938861/bin/mmc9.xlsx Hsapiens 23 44445 44448 44445 44448 44448 44448 44452 44445 44448 44448 44448 44443 44448 44448 44445 44448 44448 44444 44448 44444 44444 44448 44448"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
##  [43] "PMC8937020 /pmc/articles/PMC8937020/bin/Table1.XLSX Hsapiens 5 44621 44631 44896 44813 44628"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
##  [44] "PMC8925074 /pmc/articles/PMC8925074/bin/13073_2022_1036_MOESM4_ESM.xlsx Hsapiens 47 44256 44256 44256 44451 44260 44263 44260 44263 44263 44440 44260 44260 44257 44257 44257 44257 44257 44257 44257 44256 44257 44257 44257 44257 44257 44263 44257 44257 44257 44257 44257 44257 44263 44263 44260 44449 44256 44257 44257 44257 44257 44257 44257 44257 44257 44449 44449"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
##  [45] "PMC8903709 /pmc/articles/PMC8903709/bin/11658_2022_306_MOESM3_ESM.xls Hsapiens 26 2021/12/01 2021/03/10 2021/03/11 2021/03/01 2021/03/02 2021/03/03 2021/03/04 2021/03/05 2021/03/06 2021/03/07 2021/03/08 2021/03/09 2021/09/15 2021/09/10 2021/09/11 2021/09/12 2021/09/14 2021/09/01 2021/09/02 2021/09/03 2021/09/04 2021/09/05 2021/09/06 2021/09/07 2021/09/08 2021/09/09"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
##  [46] "PMC8934046 /pmc/articles/PMC8934046/bin/peerj-10-13138-s002.xlsx Rnorvegicus 25 37500 42248 39692 40787 40422 40057 39508 38596 38231 37316 37316 39326 38412 39142 36951 38961 37681 39873 37135 40603 40238 36951 41153 41883 37865"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
##  [47] "PMC8931337 /pmc/articles/PMC8931337/bin/Table2.XLSX Hsapiens 7 44265 44443 44265 44257 44447 44443 44446"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
##  [48] "PMC8930846 /pmc/articles/PMC8930846/bin/Table1.XLSX Rnorvegicus 5 44256 44446 44259 44266 44256"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
##  [49] "PMC8930846 /pmc/articles/PMC8930846/bin/Table1.XLSX Mmusculus 3 44448 44446 44454"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
##  [50] "PMC8930846 /pmc/articles/PMC8930846/bin/Table1.XLSX Mmusculus 3 44446 44454 44266"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
##  [51] "PMC8930846 /pmc/articles/PMC8930846/bin/Table1.XLSX Mmusculus 6 44258 44442 44447 44445 44446 44256"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
##  [52] "PMC8883549 /pmc/articles/PMC8883549/bin/2020_274258_MA_TABLES_SUPPL.xlsx Hsapiens 3 43168 43168 43345"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
##  [53] "PMC8883549 /pmc/articles/PMC8883549/bin/2020_274258_MA_TABLES_SUPPL.xlsx Hsapiens 2 43164 43164"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
##  [54] "PMC8883549 /pmc/articles/PMC8883549/bin/2020_274258_MA_TABLES_SUPPL.xlsx Hsapiens 1 43345"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
##  [55] "PMC8883549 /pmc/articles/PMC8883549/bin/2020_274258_MA_TABLES_SUPPL.xlsx Hsapiens 1 43168"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
##  [56] "PMC8883549 /pmc/articles/PMC8883549/bin/2020_274258_MA_TABLES_SUPPL.xlsx Hsapiens 1 43164"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
##  [57] "PMC8883538 /pmc/articles/PMC8883538/bin/2020_257246_WEINREB_TABLES_SUPPL.xlsx Drerio 1 44077"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
##  [58] "PMC8930202 /pmc/articles/PMC8930202/bin/Table_1.xlsx Hsapiens 37 43712 43710 43710 43722 43531 43710 43717 43717 43717 43526 43532 43712 43532 43531 43525 43716 43526 43528 43526 43528 43717 43532 43532 43525 43719 43717 43717 43711 43800 43717 43531 43531 43531 43531 43714 43722 43532"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
##  [59] "PMC8930202 /pmc/articles/PMC8930202/bin/Table_1.xlsx Hsapiens 4 43710 43525 43526 43723"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
##  [60] "PMC8930202 /pmc/articles/PMC8930202/bin/Table_1.xlsx Hsapiens 26 43710 43712 43526 43722 43532 43717 43531 43800 43525 43534 43535 43527 43528 43529 43530 43533 43723 43709 43718 43719 43720 43711 43713 43714 43715 43716"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
##  [61] "PMC8930202 /pmc/articles/PMC8930202/bin/Table_1.xlsx Hsapiens 2 43526 43712"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
##  [62] "PMC8930202 /pmc/articles/PMC8930202/bin/Table_1.xlsx Hsapiens 3 43800 43525 43526"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
##  [63] "PMC8927907 /pmc/articles/PMC8927907/bin/mmc6.xlsx Hsapiens 1 39701"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
##  [64] "PMC8927698 /pmc/articles/PMC8927698/bin/Table2.XLSX Hsapiens 26 44811 44806 44627 44626 44896 44807 44623 44814 44625 44805 44631 44810 44818 44815 44813 44808 44630 44809 44629 44622 44816 44624 44628 44812 44819 44621"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
##  [65] "PMC8927698 /pmc/articles/PMC8927698/bin/Table2.XLSX Hsapiens 26 44811 44806 44627 44626 44896 44807 44623 44814 44625 44805 44631 44810 44818 44815 44813 44808 44630 44809 44629 44622 44816 44624 44628 44812 44819 44621"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
##  [66] "PMC8927698 /pmc/articles/PMC8927698/bin/Table3.XLS Hsapiens 26 44811 44806 44627 44626 44896 44807 44623 44814 44625 44805 44631 44810 44818 44815 44813 44808 44630 44809 44629 44622 44816 44624 44628 44812 44819 44621"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
##  [67] "PMC8927698 /pmc/articles/PMC8927698/bin/Table3.XLS Hsapiens 26 44811 44806 44627 44626 44896 44807 44623 44814 44625 44805 44631 44810 44818 44815 44813 44808 44630 44809 44629 44622 44816 44624 44628 44812 44819 44621"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
##  [68] "PMC8891275 /pmc/articles/PMC8891275/bin/41467_2022_28719_MOESM5_ESM.xlsx Hsapiens 1 44448"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
##  [69] "PMC8885711 /pmc/articles/PMC8885711/bin/41467_2022_28661_MOESM39_ESM.xlsx Hsapiens 32 44811 44810 44805 44815 44627 44623 44813 44806 44621 44626 44625 44811 44810 44815 44805 44627 44626 44621 44813 44806 44625 44626 44622 44621 44627 44815 44811 44810 44625 44805 44806 44813"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
##  [70] "PMC8885711 /pmc/articles/PMC8885711/bin/41467_2022_28661_MOESM39_ESM.xlsx Hsapiens 46 44806 44809 44810 44626 44628 44815 44623 44625 44621 44818 44819 44627 44621 44813 44896 44622 44807 44630 44622 44814 44812 44811 44624 44806 44809 44810 44626 44628 44815 44623 44625 44621 44818 44819 44627 44621 44813 44896 44622 44807 44630 44622 44814 44812 44811 44624"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
##  [71] "PMC8881579 /pmc/articles/PMC8881579/bin/41467_2022_28682_MOESM4_ESM.xlsx Hsapiens 3 43526 43526 43528"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
##  [72] "PMC8863982 /pmc/articles/PMC8863982/bin/41467_2022_28554_MOESM3_ESM.xlsx Mmusculus 2 43898 44079"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
##  [73] "PMC8923467 /pmc/articles/PMC8923467/bin/pgen.1010106.s012.xlsx Scerevisiae 1 44470"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
##  [74] "PMC8921613 /pmc/articles/PMC8921613/bin/supplementary_table_s4_bbab548.xlsx Hsapiens 1 44256"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
##  [75] "PMC8919059 /pmc/articles/PMC8919059/bin/DataSheet_2.xlsx Hsapiens 1 44448"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
##  [76] "PMC8919059 /pmc/articles/PMC8919059/bin/DataSheet_5.xlsx Hsapiens 2 44442 44259"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
##  [77] "PMC8919059 /pmc/articles/PMC8919059/bin/DataSheet_5.xlsx Hsapiens 2 44442 44259"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
##  [78] "PMC8912178 /pmc/articles/PMC8912178/bin/pone.0265008.s011.xlsx Hsapiens 20 44259 44262 44441 44447 44451 44444 44448 44443 44257 44449 44261 44266 44446 44256 44445 44256 44442 44450 44263 44260"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
##  [79] "PMC8912178 /pmc/articles/PMC8912178/bin/pone.0265008.s011.xlsx Hsapiens 2 44263 44260"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
##  [80] "PMC8912178 /pmc/articles/PMC8912178/bin/pone.0265008.s012.xlsx Hsapiens 20 44259 44262 44441 44447 44451 44444 44448 44443 44257 44449 44261 44266 44446 44256 44445 44256 44442 44450 44263 44260"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
##  [81] "PMC8892733 /pmc/articles/PMC8892733/bin/12885_2022_9328_MOESM6_ESM.xlsx Hsapiens 1 44263"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
##  [82] "PMC8896830 /pmc/articles/PMC8896830/bin/elife-69476-supp1.xlsx Mmusculus 1 37104"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
##  [83] "PMC8831532 /pmc/articles/PMC8831532/bin/41467_2022_28434_MOESM12_ESM.xlsx Drerio 24 38412 37865 39508 39873 38047 37530 37316 39508 38961 38777 38961 39508 39508 38777 41153 39142 41153 41153 39142 40422 38231 39508 37865 39142"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
##  [84] "PMC8831532 /pmc/articles/PMC8831532/bin/41467_2022_28434_MOESM4_ESM.xlsx Drerio 8 37316 38961 38961 38777 41153 40422 38231 39508"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
##  [85] "PMC8831532 /pmc/articles/PMC8831532/bin/41467_2022_28434_MOESM4_ESM.xlsx Drerio 5 38961 38961 41153 40422 38231"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
##  [86] "PMC8831532 /pmc/articles/PMC8831532/bin/41467_2022_28434_MOESM4_ESM.xlsx Drerio 3 37316 38777 39508"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
##  [87] "PMC8831532 /pmc/articles/PMC8831532/bin/41467_2022_28434_MOESM6_ESM.xlsx Drerio 28 38961 38961 38961 38961 38961 38961 38231 38231 38231 38231 38231 38231 38231 38231 38231 38231 41153 41153 41153 41153 41153 41153 41153 41153 40422 40422 40422 40422"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
##  [88] "PMC8888678 /pmc/articles/PMC8888678/bin/Table1.XLSX Hsapiens 96 8-Mar 8-Mar 8-Mar 8-Mar 8-Mar 8-Mar 8-Mar 8-Mar 1-Dec 1-Dec 1-Dec 1-Dec 7-Mar 7-Mar 7-Mar 7-Mar 14-Sep 14-Sep 14-Sep 14-Sep 12-Sep 12-Sep 12-Sep 12-Sep 6-Sep 6-Sep 6-Sep 6-Sep 4-Mar 4-Mar 4-Mar 4-Mar 11-Mar 11-Mar 11-Mar 11-Mar 2-Mar 2-Mar 2-Mar 2-Mar 10-Mar 10-Mar 10-Mar 10-Mar 11-Sep 11-Sep 11-Sep 11-Sep 8-Mar 8-Mar 8-Mar 8-Mar 1-Sep 1-Sep 1-Sep 1-Sep 2-Sep 2-Sep 2-Sep 2-Sep 15-Sep 15-Sep 15-Sep 15-Sep 3-Mar 3-Mar 3-Mar 3-Mar 10-Sep 10-Sep 10-Sep 10-Sep 1-Mar 1-Mar 1-Mar 1-Mar 3-Sep 3-Sep 3-Sep 3-Sep 5-Sep 5-Sep 5-Sep 5-Sep 6-Mar 6-Mar 6-Mar 6-Mar 7-Sep 7-Sep 7-Sep 7-Sep 9-Sep 9-Sep 9-Sep 9-Sep"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
##  [89] "PMC8888678 /pmc/articles/PMC8888678/bin/Table1.XLSX Hsapiens 96 8-Mar 8-Mar 8-Mar 8-Mar 8-Mar 8-Mar 8-Mar 8-Mar 1-Dec 1-Dec 1-Dec 1-Dec 7-Mar 7-Mar 7-Mar 7-Mar 14-Sep 14-Sep 14-Sep 14-Sep 12-Sep 12-Sep 12-Sep 12-Sep 6-Sep 6-Sep 6-Sep 6-Sep 4-Mar 4-Mar 4-Mar 4-Mar 11-Mar 11-Mar 11-Mar 11-Mar 2-Mar 2-Mar 2-Mar 2-Mar 10-Mar 10-Mar 10-Mar 10-Mar 11-Sep 11-Sep 11-Sep 11-Sep 8-Mar 8-Mar 8-Mar 8-Mar 1-Sep 1-Sep 1-Sep 1-Sep 2-Sep 2-Sep 2-Sep 2-Sep 15-Sep 15-Sep 15-Sep 15-Sep 3-Mar 3-Mar 3-Mar 3-Mar 10-Sep 10-Sep 10-Sep 10-Sep 1-Mar 1-Mar 1-Mar 1-Mar 3-Sep 3-Sep 3-Sep 3-Sep 5-Sep 5-Sep 5-Sep 5-Sep 6-Mar 6-Mar 6-Mar 6-Mar 7-Sep 7-Sep 7-Sep 7-Sep 9-Sep 9-Sep 9-Sep 9-Sep"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
##  [90] "PMC8888678 /pmc/articles/PMC8888678/bin/Table1.XLSX Hsapiens 22 8-Mar 1-Dec 7-Mar 14-Sep 12-Sep 6-Sep 4-Mar 11-Mar 2-Mar 10-Mar 11-Sep 1-Sep 2-Sep 15-Sep 3-Mar 10-Sep 1-Mar 3-Sep 5-Sep 6-Mar 7-Sep 9-Sep"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
##  [91] "PMC8885993 /pmc/articles/PMC8885993/bin/Table3.XLSX Hsapiens 5 44445 44450 44440 44443 44266"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
##  [92] "PMC8885993 /pmc/articles/PMC8885993/bin/Table3.XLSX Ggallus 4 44445 44443 44440 44259"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
##  [93] "PMC8885993 /pmc/articles/PMC8885993/bin/Table3.XLSX Hsapiens 2 44266 44259"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
##  [94] "PMC8885993 /pmc/articles/PMC8885993/bin/Table3.XLSX Hsapiens 5 44266 44449 44450 44445 44531"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
##  [95] "PMC8885993 /pmc/articles/PMC8885993/bin/Table5.XLSX Hsapiens 8 44449 44450 44531 44266 44440 44443 44445 44259"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
##  [96] "PMC8884250 /pmc/articles/PMC8884250/bin/Table_2.xls Hsapiens 2 2021/03/04 2021/09/14"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
##  [97] "PMC8967178 /pmc/articles/PMC8967178/bin/Table_2.XLSX Hsapiens 1 44264"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
##  [98] "PMC8967178 /pmc/articles/PMC8967178/bin/Table_3.XLSX Hsapiens 5 44261 44261 44260 44260 44262"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
##  [99] "PMC8966188 /pmc/articles/PMC8966188/bin/12915_2022_1269_MOESM9_ESM.xlsx Hsapiens 15 43897 44076 44081 43899 44085 43892 44082 43893 44084 43892 44079 44078 44083 43896 44080"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
## [100] "PMC8960263 /pmc/articles/PMC8960263/bin/Table6.XLSX Hsapiens 2 44621 44805"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
## [101] "PMC8959321 /pmc/articles/PMC8959321/bin/Table_1.xlsx Hsapiens 1 44256"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
## [102] "PMC8959321 /pmc/articles/PMC8959321/bin/Table_1.xlsx Hsapiens 1 44896"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
## [103] "PMC8959321 /pmc/articles/PMC8959321/bin/Table_1.xlsx Hsapiens 1 44623"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
## [104] "PMC8959321 /pmc/articles/PMC8959321/bin/Table_1.xlsx Hsapiens 2 44626 44623"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
## [105] "PMC8959321 /pmc/articles/PMC8959321/bin/Table_1.xlsx Hsapiens 6 44629 44621 44819 44624 44629 44623"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
## [106] "PMC8942222 /pmc/articles/PMC8942222/bin/pone.0264776.s021.xlsx Drerio 7 44257 44445 44262 44261 44441 44449 44260"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
## [107] "PMC8942222 /pmc/articles/PMC8942222/bin/pone.0264776.s022.xlsx Drerio 1 44257"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
## [108] "PMC8942222 /pmc/articles/PMC8942222/bin/pone.0264776.s023.xlsx Drerio 4 44445 44261 44263 44441"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
## [109] "PMC8904843 /pmc/articles/PMC8904843/bin/42003_2022_3117_MOESM7_ESM.xlsx Hsapiens 3 44257 44442 44256"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
## [110] "PMC8916121 /pmc/articles/PMC8916121/bin/JEM_20211121_TableS6.xlsx Hsapiens 10 37316 39873 39142 37681 36951 36951 39508 38412 38777 37316"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
## [111] "PMC8916121 /pmc/articles/PMC8916121/bin/JEM_20211121_TableS6.xlsx Hsapiens 7 38777 38412 36951 37681 39142 39873 37316"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
## [112] "PMC8916121 /pmc/articles/PMC8916121/bin/JEM_20211121_TableS6.xlsx Hsapiens 7 37316 37681 38412 38777 39873 36951 39142"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
## [113] "PMC8916121 /pmc/articles/PMC8916121/bin/JEM_20211121_TableS6.xlsx Hsapiens 7 38777 38412 36951 37681 39142 39873 37316"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
## [114] "PMC8916121 /pmc/articles/PMC8916121/bin/JEM_20211121_TableS6.xlsx Hsapiens 6 39142 36951 39873 38412 37316 38777"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
## [115] "PMC8916121 /pmc/articles/PMC8916121/bin/JEM_20211121_TableS6.xlsx Hsapiens 6 39142 38412 37316 38777 39873 36951"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
## [116] "PMC8891017 /pmc/articles/PMC8891017/bin/41586_2022_4394_MOESM4_ESM.xlsx Hsapiens 2 39508 39508"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
## [117] "PMC8891017 /pmc/articles/PMC8891017/bin/41586_2022_4394_MOESM4_ESM.xlsx Hsapiens 2 39508 39508"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
## [118] "PMC8891017 /pmc/articles/PMC8891017/bin/41586_2022_4394_MOESM4_ESM.xlsx Hsapiens 2 39508 39508"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
## [119] "PMC8891017 /pmc/articles/PMC8891017/bin/41586_2022_4394_MOESM4_ESM.xlsx Hsapiens 2 39508 39508"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
## [120] "PMC8891017 /pmc/articles/PMC8891017/bin/41586_2022_4394_MOESM4_ESM.xlsx Hsapiens 23 39508 39508 39508 39508 39508 39508 39508 39508 39508 39508 39508 39508 39508 39508 39508 39508 39508 39508 39508 39508 39508 39508 39508"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
## [121] "PMC8933692 /pmc/articles/PMC8933692/bin/mmc2.xlsx Mmusculus 78 44256 44256 44256 44257 44257 44450 44450 44450 44450 44450 44450 44450 44263 44440 44447 44447 44447 44447 44447 44443 44265 44265 44265 44265 44265 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44261 44442 44451 44444 44444 44444 44258 44258 44258 44258 44258"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
## [122] "PMC8933692 /pmc/articles/PMC8933692/bin/mmc4.xlsx Mmusculus 8 44448 44448 44448 44448 44448 44448 44258 44258"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
## [123] "PMC8933692 /pmc/articles/PMC8933692/bin/mmc4.xlsx Mmusculus 44 44256 44256 44257 44257 44450 44450 44450 44450 44450 44263 44440 44447 44447 44443 44265 44265 44265 44265 44265 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44442 44451 44444 44444 44258 44258"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
## [124] "PMC8933692 /pmc/articles/PMC8933692/bin/mmc4.xlsx Mmusculus 70 44256 44256 44256 44257 44257 44450 44450 44450 44450 44450 44450 44450 44263 44440 44447 44447 44447 44447 44447 44443 44265 44265 44265 44265 44265 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44261 44442 44451 44444 44444 44444 44258 44258 44258"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
## [125] "PMC8933692 /pmc/articles/PMC8933692/bin/mmc4.xlsx Mmusculus 34 44256 44450 44450 44447 44447 44447 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44448 44261 44444 44258 44258 44258"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
## [126] "PMC8931336 /pmc/articles/PMC8931336/bin/pnas.2119415119.sd01.xlsx Mmusculus 18 44076 43892 44084 43899 44082 44078 44083 44077 43896 43892 43893 43895 43897 44085 43898 44075 44081 44080"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
## [127] "PMC8925295 /pmc/articles/PMC8925295/bin/41598_2022_8619_MOESM2_ESM.xlsx Hsapiens 1 44819"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
## [128] "PMC8925295 /pmc/articles/PMC8925295/bin/41598_2022_8619_MOESM2_ESM.xlsx Hsapiens 2 44631 44624"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
## [129] "PMC8925295 /pmc/articles/PMC8925295/bin/41598_2022_8619_MOESM2_ESM.xlsx Hsapiens 3 44624 44629 44818"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
## [130] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_3.xlsx Hsapiens 20 44440 44449 44448 44441 44449 44440 44449 44449 44446 44446 44446 44444 44445 44444 44446 44444 44444 44256 44444 44442"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
## [131] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_3.xlsx Hsapiens 4 44444 44450 44442 44447"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
## [132] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 4 44264 44258 44257 44446"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
## [133] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 8 44264 44256 44257 44445 44258 44440 44261 44448"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
## [134] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 8 44445 44257 44256 44446 44258 44443 44262 44259"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
## [135] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 2 44256 44262"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
## [136] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 18 44445 44448 44449 44257 44446 44453 44265 44441 44256 44261 44443 44447 44260 44266 44263 44444 44259 44442"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
## [137] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 15 44257 44258 44441 44447 44446 44259 44444 44443 44440 44256 44450 44262 44263 44260 44442"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
## [138] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 10 44450 44447 44258 44261 44445 44440 44446 44260 44443 44451"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
## [139] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 14 44440 44445 44443 44257 44263 44261 44447 44444 44262 44450 44260 44264 44531 44256"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
## [140] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 3 44256 44258 44259"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
## [141] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 10 44450 44258 44447 44443 44256 44445 44263 44442 44261 44265"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
## [142] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 16 44445 44440 44443 44263 44446 44449 44450 44259 44257 44531 44265 44261 44444 44447 44264 44442"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
## [143] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 17 44450 44449 44265 44266 44447 44262 44259 44445 44264 44446 44261 44444 44263 44442 44256 44443 44448"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
## [144] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 6 44264 44448 44451 44258 44449 44440"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
## [145] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 14 44264 44450 44449 44446 44447 44444 44257 44443 44260 44256 44451 44262 44263 44266"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
## [146] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 5 44443 44445 44450 44448 44264"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
## [147] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 9 44444 44442 44256 44440 44258 44261 44449 44262 44266"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
## [148] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 11 44256 44440 44445 44448 44262 44258 44442 44444 44263 44443 44259"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
## [149] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 8 44440 44445 44443 44450 44263 44256 44261 44447"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
## [150] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 6 44440 44442 44256 44451 44257 44260"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
## [151] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 11 44445 44440 44258 44261 44264 44257 44444 44260 44441 44262 44446"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
## [152] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 16 44449 44264 44441 44447 44450 44263 44261 44256 44448 44440 44265 44446 44445 44260 44262 44443"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
## [153] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 13 44445 44440 44450 44256 44449 44446 44451 44265 44261 44260 44257 44264 44444"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
## [154] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 10 44264 44449 44262 44263 44257 44446 44265 44450 44256 44440"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
## [155] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 13 44257 44264 44263 44449 44446 44262 44450 44260 44261 44447 44441 44448 44443"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
## [156] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 11 44446 44264 44449 44263 44447 44262 44444 44260 44261 44453 44445"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
## [157] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 13 44443 44445 44264 44440 44448 44450 44444 44258 44442 44441 44256 44446 44262"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
## [158] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 10 44449 44448 44450 44261 44440 44262 44442 44264 44265 44256"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
## [159] "PMC8924366 /pmc/articles/PMC8924366/bin/Table_4.xlsx Hsapiens 5 44440 44443 44445 44260 44441"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
## [160] "PMC8921511 /pmc/articles/PMC8921511/bin/41598_2022_8356_MOESM2_ESM.xlsx Hsapiens 1 37226"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
## [161] "PMC8921118 /pmc/articles/PMC8921118/bin/345_2022_3936_MOESM2_ESM.xlsx Hsapiens 11 44454 44445 44441 44446 44256 44447 44257 44450 44260 44449 44448"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
## [162] "PMC8888590 /pmc/articles/PMC8888590/bin/41467_2022_28705_MOESM4_ESM.xlsx Hsapiens 2 38412 38961"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
## [163] "PMC8885418 /pmc/articles/PMC8885418/bin/41375_2021_1461_MOESM11_ESM.xlsx Mmusculus 128 37135 37135 37135 40422 40422 40422 40787 40787 40787 41153 41153 41153 41883 41883 41883 42248 42248 42248 37500 37500 37500 37865 37865 37865 38231 38231 38231 38596 38596 38596 38961 38961 38961 39326 39326 39326 39692 39692 39692 40057 40057 40057 37012 37012 37012 38108 38108 38108 1-Mar 1-Mar 1-Mar 44075 44075 44075 10-Mar 10-Mar 10-Mar 44084 44084 44084 11-Mar 11-Mar 11-Mar 44085 44085 44085 44086 44086 44086 44088 44088 44088 44089 44089 44089 2-Mar 2-Mar 2-Mar 44076 44076 44076 3-Mar 3-Mar 3-Mar 44077 44077 44077 4-Mar 4-Mar 4-Mar 44078 44078 44078 5-Mar 5-Mar 5-Mar 44079 44079 44079 6-Mar 6-Mar 44080 44080 44080 7-Mar 7-Mar 7-Mar 44081 44081 44081 8-Mar 8-Mar 8-Mar 44082 44082 44082 9-Mar 9-Mar 9-Mar 44083 44083 44083 37012 37012 37012 38108 38108 38108"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
## [164] "PMC8885418 /pmc/articles/PMC8885418/bin/41375_2021_1461_MOESM12_ESM.xlsx Mmusculus 128 37135 37135 37135 40422 40422 40422 40787 40787 40787 41153 41153 41153 41883 41883 41883 42248 42248 42248 37500 37500 37500 37865 37865 37865 38231 38231 38231 38596 38596 38596 38961 38961 38961 39326 39326 39326 39692 39692 39692 40057 40057 40057 37012 37012 37012 38108 38108 38108 1-Mar 1-Mar 1-Mar 44075 44075 44075 10-Mar 10-Mar 10-Mar 44084 44084 44084 11-Mar 11-Mar 11-Mar 44085 44085 44085 44086 44086 44086 44088 44088 44088 44089 44089 44089 2-Mar 2-Mar 2-Mar 44076 44076 44076 3-Mar 3-Mar 3-Mar 44077 44077 44077 4-Mar 4-Mar 4-Mar 44078 44078 44078 5-Mar 5-Mar 5-Mar 44079 44079 44079 6-Mar 6-Mar 44080 44080 44080 7-Mar 7-Mar 7-Mar 44081 44081 44081 8-Mar 8-Mar 8-Mar 44082 44082 44082 9-Mar 9-Mar 9-Mar 44083 44083 44083 37012 37012 37012 38108 38108 38108"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
## [165] "PMC8885418 /pmc/articles/PMC8885418/bin/41375_2021_1461_MOESM12_ESM.xlsx Mmusculus 40 37135 40422 44080 11-Mar 37012 37500 37865 38108 39326 39692 40787 44075 44077 44083 44084 10-Mar 1-Mar 4-Mar 6-Mar 9-Mar 38231 38596 38961 40057 41153 41883 42248 44076 44078 44079 44081 44082 44085 44086 44088 2-Mar 3-Mar 5-Mar 7-Mar 8-Mar"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
## [166] "PMC8885418 /pmc/articles/PMC8885418/bin/41375_2021_1461_MOESM8_ESM.xlsx Mmusculus 7 39692 39326 37135 38231 40422 38108 37500"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
## [167] "PMC8885418 /pmc/articles/PMC8885418/bin/41375_2021_1461_MOESM8_ESM.xlsx Mmusculus 7 39692 39326 37135 38231 40422 38108 37500"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
## [168] "PMC8885418 /pmc/articles/PMC8885418/bin/41375_2021_1461_MOESM8_ESM.xlsx Mmusculus 7 39692 39326 37135 38231 40422 38108 37500"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
## [169] "PMC8885418 /pmc/articles/PMC8885418/bin/41375_2021_1461_MOESM8_ESM.xlsx Mmusculus 7 39692 39326 37135 38231 40422 38108 37500"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
## [170] "PMC8885418 /pmc/articles/PMC8885418/bin/41375_2021_1461_MOESM9_ESM.xlsx Mmusculus 10 37500 40787 37135 39326 40422 39692 38231 40057 38596 38961"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
## [171] "PMC8873204 /pmc/articles/PMC8873204/bin/41467_2022_28569_MOESM5_ESM.xlsx Hsapiens 1 39692"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
## [172] "PMC8873204 /pmc/articles/PMC8873204/bin/41467_2022_28569_MOESM5_ESM.xlsx Hsapiens 1 40057"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
## [173] "PMC8864016 /pmc/articles/PMC8864016/bin/41467_2022_28657_MOESM4_ESM.xlsx Mmusculus 2 43348 43349"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
## [174] "PMC8864016 /pmc/articles/PMC8864016/bin/41467_2022_28657_MOESM5_ESM.xlsx Mmusculus 1 43167"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
## [175] "PMC8861042 /pmc/articles/PMC8861042/bin/41467_2022_28634_MOESM4_ESM.xlsx Hsapiens 8 37500 38777 38961 39508 38412 39326 37316 38777"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
## [176] "PMC8923497 /pmc/articles/PMC8923497/bin/pone.0264645.s002.xls Hsapiens 3 2021/03/10 2021/12/01 2021/03/11"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
## [177] "PMC8921988 /pmc/articles/PMC8921988/bin/DataSheet_3.xlsx Hsapiens 1 44450"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
## [178] "PMC8915965 /pmc/articles/PMC8915965/bin/pnas.2119676119.sd01.xlsx Hsapiens 26 41335 41527 41608 41343 41528 41334 41519 41525 41526 41531 41517 41336 41520 41338 41341 41333 41340 41521 41530 41524 41337 41518 41522 41523 41342 41339"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
## [179] "PMC8913945 /pmc/articles/PMC8913945/bin/DataSheet_6.xls Hsapiens 2 44443 44265"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
## [180] "PMC8913945 /pmc/articles/PMC8913945/bin/DataSheet_7.xls Hsapiens 23 44445 44445 44445 44445 44445 44445 44445 44445 44445 44445 44445 44445 44445 44445 44445 44445 44445 44445 44443 44443 44443 44443 44443"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
## [181] "PMC8913945 /pmc/articles/PMC8913945/bin/DataSheet_7.xls Ggallus 23 44445 44445 44445 44445 44445 44445 44445 44445 44445 44445 44445 44445 44445 44445 44445 44445 44445 44445 44443 44443 44443 44443 44443"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
## [182] "PMC8907571 /pmc/articles/PMC8907571/bin/Table_1.xlsx Hsapiens 13 44454 44257 44454 44261 44263 44257 44257 44262 44261 44258 44263 44260 44257"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
## [183] "PMC8891552 /pmc/articles/PMC8891552/bin/CPR-55-e13195-s002.xlsx Mmusculus 5 44446 44441 44262 44454 44449"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
## [184] "PMC8891552 /pmc/articles/PMC8891552/bin/CPR-55-e13195-s002.xlsx Mmusculus 4 44261 44265 44257 44263"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
## [185] "PMC8891552 /pmc/articles/PMC8891552/bin/CPR-55-e13195-s004.xlsx Mmusculus 2 44447 44448"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
## [186] "PMC8891552 /pmc/articles/PMC8891552/bin/CPR-55-e13195-s004.xlsx Mmusculus 4 44262 44266 44258 44256"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
## [187] "PMC8891552 /pmc/articles/PMC8891552/bin/CPR-55-e13195-s009.xlsx Mmusculus 6 43891 43891 43893 43897 43891 43901"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
## [188] "PMC8905247 /pmc/articles/PMC8905247/bin/DataSheet1.XLSX Hsapiens 2 44256 44257"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
## [189] "PMC8902468 /pmc/articles/PMC8902468/bin/Table_2.xlsx Athaliana 6 44476 44476 44416 44476 44476 44473"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
## [190] "PMC8896005 /pmc/articles/PMC8896005/bin/jkac009_table_s3.xlsx Celegans 8 44440 44260 44440 44260 44440 44260 44440 44260"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
## [191] "PMC8894600 /pmc/articles/PMC8894600/bin/DataSheet_1.xls Hsapiens 3 2021/03/05 2021/03/05 2021/03/05"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
## [192] "PMC8892324 /pmc/articles/PMC8892324/bin/pnas.2111404119.sd02.xlsx Hsapiens 24 \"LJP007 HA1E 24H-HG-9-91-01-10\" \"LJP005 PC3 24H-HG-5-113-01-10\" \"LJP006 HA1E 24H-THZ-2-98-01-10\" \"LJP006 HME1 24H-THZ-2-98-01-10\" \"CPC007 A375 24H-ncgc00188535-01-10.0\" \"LJP005 HEPG2 24H-HG-5-113-01-10\" \"LJP005 MCF7 3H-HG-5-113-01-10\" \"LJP006 HS578T 3H-HG-6-64-01-10\""                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
## [193] "PMC8891516 /pmc/articles/PMC8891516/bin/Table5.xlsx Hsapiens 34 44258 44257 44531 44262 44261 44256 44531 44531 44259 44257 44263 44257 44531 44531 44258 44531 44256 44257 44259 44263 44265 44531 44261 44266 44256 44531 44259 44262 44259 44256 44261 44264 44261 44259"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
## [194] "PMC8891516 /pmc/articles/PMC8891516/bin/Table5.xlsx Hsapiens 36 44258 44262 44531 44257 44261 44531 44257 44531 44259 44257 44256 44531 44263 44531 44531 44256 44264 44263 44256 44261 44258 44265 44256 44257 44531 44261 44531 44257 44256 44259 44258 44261 44259 44256 44259 44265"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
## [195] "PMC8891516 /pmc/articles/PMC8891516/bin/Table5.xlsx Hsapiens 33 44258 44257 44531 44531 44257 44265 44256 44263 44531 44258 44261 44531 44259 44262 44259 44259 44259 44531 44531 44531 44256 44256 44258 44256 44256 44258 44258 44531 44258 44257 44256 44256 44531"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
## [196] "PMC8891516 /pmc/articles/PMC8891516/bin/Table5.xlsx Hsapiens 36 44258 44531 44258 44259 44257 44531 44531 44263 44257 44261 44259 44256 44256 44256 44531 44531 44257 44257 44259 44265 44258 44256 44531 44258 44256 44531 44259 44257 44262 44531 44531 44256 44256 44256 44262 44531"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
## [197] "PMC8891516 /pmc/articles/PMC8891516/bin/Table6.xlsx Hsapiens 6 44259 44256 44258 44531 44258 44256"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
## [198] "PMC8891516 /pmc/articles/PMC8891516/bin/Table6.xlsx Hsapiens 2 44263 44261"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
## [199] "PMC8889144 /pmc/articles/PMC8889144/bin/Table1.XLSX Hsapiens 4 Histone Methylation: https://www.nature.com/articles/s12276-019-0230-6 https://clincancerres.aacrjournals.org/content/clincanres/early/2016/02/26/1078-0432.CCR-13-1333.full.pdf"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
## [200] "PMC8844066 /pmc/articles/PMC8844066/bin/41421_2021_366_MOESM3_ESM.xlsx Hsapiens 15 43901 43891 43901 43901 43891 43901 43901 43891 43901 43891 43901 43891 43901 43891 43901"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
## [201] "PMC8837555 /pmc/articles/PMC8837555/bin/41588_2021_1008_MOESM3_ESM.xlsx Mmusculus 4 43165 43165 43165 43165"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
## [202] "PMC8837555 /pmc/articles/PMC8837555/bin/41588_2021_1008_MOESM3_ESM.xlsx Mmusculus 3 44075 44083 44077"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
## [203] "PMC8837555 /pmc/articles/PMC8837555/bin/41588_2021_1008_MOESM3_ESM.xlsx Mmusculus 2 43896 43898"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
## [204] "PMC8837555 /pmc/articles/PMC8837555/bin/41588_2021_1008_MOESM3_ESM.xlsx Mmusculus 2 44077 44079"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
## [205] "PMC8837555 /pmc/articles/PMC8837555/bin/41588_2021_1008_MOESM3_ESM.xlsx Mmusculus 2 41888 41893"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
## [206] "PMC8837555 /pmc/articles/PMC8837555/bin/41588_2021_1008_MOESM3_ESM.xlsx Mmusculus 1 44257"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
## [207] "PMC8837555 /pmc/articles/PMC8837555/bin/41588_2021_1008_MOESM3_ESM.xlsx Mmusculus 1 44258"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
## [208] "PMC8837555 /pmc/articles/PMC8837555/bin/41588_2021_1008_MOESM3_ESM.xlsx Mmusculus 2 44261 44264"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
## [209] "PMC8887668 /pmc/articles/PMC8887668/bin/Table5.xlsx Drerio 1 43892"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
## [210] "PMC8885996 /pmc/articles/PMC8885996/bin/Table_2.xlsx Mmusculus 2 43892 44078"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
## [211] "PMC8884696 /pmc/articles/PMC8884696/bin/Table3.xlsx Hsapiens 2 44256 44257"

In depth look at the errors

Let’s investigate the errors in more detail.

# By species
SPECIES <- sapply(strsplit(ERROR_GENELISTS," "),"[[",3)
table(SPECIES)
## SPECIES
##   Athaliana    Celegans      Drerio     Ggallus    Hsapiens   Mmusculus 
##           1           1          10           4         143          45 
## Rnorvegicus Scerevisiae 
##           6           1
par(mar=c(5,12,4,2))
barplot(table(SPECIES),horiz=TRUE,las=1)

par(mar=c(5,5,4,2))

# Number of affected Excel files per paper
DIST <- table(sapply(strsplit(ERROR_GENELISTS," "),"[[",1))
DIST
## 
## PMC8831532 PMC8837555 PMC8844066 PMC8861042 PMC8863982 PMC8864016 PMC8873204 
##          5          8          1          1          1          2          2 
## PMC8881579 PMC8883538 PMC8883549 PMC8884250 PMC8884696 PMC8885418 PMC8885711 
##          1          1          5          1          1          8          2 
## PMC8885993 PMC8885996 PMC8887668 PMC8888590 PMC8888678 PMC8889144 PMC8891017 
##          5          1          1          1          3          1          5 
## PMC8891275 PMC8891516 PMC8891552 PMC8892324 PMC8892733 PMC8894600 PMC8896005 
##          1          6          5          1          1          1          1 
## PMC8896830 PMC8902468 PMC8903709 PMC8904843 PMC8905247 PMC8907571 PMC8912178 
##          1          1          1          1          1          1          3 
## PMC8913945 PMC8915965 PMC8916121 PMC8919059 PMC8921118 PMC8921511 PMC8921613 
##          3          1          6          3          1          1          1 
## PMC8921988 PMC8923467 PMC8923497 PMC8924366 PMC8925074 PMC8925295 PMC8927698 
##          1          1          1         30          1          3          4 
## PMC8927907 PMC8930202 PMC8930846 PMC8931336 PMC8931337 PMC8933692 PMC8934046 
##          1          5          4          1          1          5          1 
## PMC8937020 PMC8938417 PMC8938861 PMC8940286 PMC8941526 PMC8941758 PMC8942222 
##          1          1          7          9          1          5          3 
## PMC8947600 PMC8957956 PMC8958363 PMC8958792 PMC8959321 PMC8960258 PMC8960263 
##          4          1          6          7          5          1          1 
## PMC8966188 PMC8967178 
##          1          2
summary(as.numeric(DIST))
##    Min. 1st Qu.  Median    Mean 3rd Qu.    Max. 
##   1.000   1.000   1.000   2.931   4.250  30.000
hist(DIST,main="Number of affected Excel files per paper")

# PMC Articles with the most errors
DIST_DF <- as.data.frame(DIST)
DIST_DF <- DIST_DF[order(-DIST_DF$Freq),,drop=FALSE]
head(DIST_DF,20)
##          Var1 Freq
## 46 PMC8924366   30
## 60 PMC8940286    9
## 2  PMC8837555    8
## 13 PMC8885418    8
## 59 PMC8938861    7
## 67 PMC8958792    7
## 23 PMC8891516    6
## 38 PMC8916121    6
## 66 PMC8958363    6
## 1  PMC8831532    5
## 10 PMC8883549    5
## 15 PMC8885993    5
## 21 PMC8891017    5
## 24 PMC8891552    5
## 51 PMC8930202    5
## 55 PMC8933692    5
## 62 PMC8941758    5
## 68 PMC8959321    5
## 49 PMC8927698    4
## 52 PMC8930846    4
MOST_ERR_FILES = as.character(DIST_DF[1,1])
MOST_ERR_FILES
## [1] "PMC8924366"
# Number of errors per paper
NERR <- as.numeric(sapply(strsplit(ERROR_GENELISTS," "),"[[",4))
names(NERR) <- sapply(strsplit(ERROR_GENELISTS," "),"[[",1)
NERR <-tapply(NERR, names(NERR), sum)
NERR
## PMC8831532 PMC8837555 PMC8844066 PMC8861042 PMC8863982 PMC8864016 PMC8873204 
##         68         17         15          8          2          3          2 
## PMC8881579 PMC8883538 PMC8883549 PMC8884250 PMC8884696 PMC8885418 PMC8885711 
##          3          1          8          2          2        334         78 
## PMC8885993 PMC8885996 PMC8887668 PMC8888590 PMC8888678 PMC8889144 PMC8891017 
##         24          2          1          2        214          4         31 
## PMC8891275 PMC8891516 PMC8891552 PMC8892324 PMC8892733 PMC8894600 PMC8896005 
##          1        147         21         24          1          3          8 
## PMC8896830 PMC8902468 PMC8903709 PMC8904843 PMC8905247 PMC8907571 PMC8912178 
##          1          6         26          3          2         13         42 
## PMC8913945 PMC8915965 PMC8916121 PMC8919059 PMC8921118 PMC8921511 PMC8921613 
##         48         26         43          5         11          1          1 
## PMC8921988 PMC8923467 PMC8923497 PMC8924366 PMC8925074 PMC8925295 PMC8927698 
##          1          1          3        310         47          6        104 
## PMC8927907 PMC8930202 PMC8930846 PMC8931336 PMC8931337 PMC8933692 PMC8934046 
##          1         72         17         18          7        234         25 
## PMC8937020 PMC8938417 PMC8938861 PMC8940286 PMC8941526 PMC8941758 PMC8942222 
##          5          2         48         11          2        120         12 
## PMC8947600 PMC8957956 PMC8958363 PMC8958792 PMC8959321 PMC8960258 PMC8960263 
##         22        332         89        151         11          2          2 
## PMC8966188 PMC8967178 
##         15          6
hist(NERR,main="number of errors per PMC article")

NERR_DF <- as.data.frame(NERR)
NERR_DF <- NERR_DF[order(-NERR_DF$NERR),,drop=FALSE]
head(NERR_DF,20)
##            NERR
## PMC8885418  334
## PMC8957956  332
## PMC8924366  310
## PMC8933692  234
## PMC8888678  214
## PMC8958792  151
## PMC8891516  147
## PMC8941758  120
## PMC8927698  104
## PMC8958363   89
## PMC8885711   78
## PMC8930202   72
## PMC8831532   68
## PMC8913945   48
## PMC8938861   48
## PMC8925074   47
## PMC8916121   43
## PMC8912178   42
## PMC8891017   31
## PMC8903709   26
MOST_ERR = rownames(NERR_DF)[1]
MOST_ERR
## [1] "PMC8885418"

Journals affected

GENELIST_ERROR_ARTICLES <- gsub("PMC","",GENELIST_ERROR_ARTICLES)

### JSON PARSING is more reliable than XML
ARTICLES <- esummary( GENELIST_ERROR_ARTICLES , db="pmc" , retmode = "json"  )
ARTICLE_DATA <- reutils::content(ARTICLES,as= "parsed")
ARTICLE_DATA <- ARTICLE_DATA$result
ARTICLE_DATA <- ARTICLE_DATA[2:length(ARTICLE_DATA)]
JOURNALS <- unlist(lapply(ARTICLE_DATA,function(x) {x$fulljournalname} ))
JOURNALS_TABLE <- table(JOURNALS)
JOURNALS_TABLE <- JOURNALS_TABLE[order(-JOURNALS_TABLE)]

length(JOURNALS_TABLE)
## [1] 35
NUM_JOURNALS=length(JOURNALS_TABLE)

par(mar=c(5,25,4,2))
barplot(head(JOURNALS_TABLE,10), horiz=TRUE, las=1, 
  xlab="Articles with gene name errors in supp files",
  main="Top journals this month")

Journal of the month winner

Congrats to our Journal of the Month winner!

JOURNAL_WINNER <- names(head(JOURNALS_TABLE,1))
JOURNAL_WINNER
## [1] "Nature Communications"

Paper of the month winners

There are two categories:

Sometimes, one paper can win both categories. Congrats to our winners.

Paper with most files affected

MOST_ERR_FILES <- gsub("PMC","",MOST_ERR_FILES)
ARTICLES <- esummary( MOST_ERR_FILES , db="pmc" , retmode = "json"  )
ARTICLE_DATA <- reutils::content(ARTICLES,as= "parsed")
ARTICLE_DATA <- ARTICLE_DATA[2]
ARTICLE_DATA
## $result
## $result$uids
## [1] "8924366"
## 
## $result$`8924366`
## $result$`8924366`$uid
## [1] "8924366"
## 
## $result$`8924366`$pubdate
## [1] "2022 Mar 2"
## 
## $result$`8924366`$epubdate
## [1] "2022 Mar 2"
## 
## $result$`8924366`$printpubdate
## [1] ""
## 
## $result$`8924366`$source
## [1] "Front Immunol"
## 
## $result$`8924366`$authors
##       name authtype
## 1   Zhao R   Author
## 2    Pan Z   Author
## 3     Li B   Author
## 4   Zhao S   Author
## 5  Zhang S   Author
## 6     Qi Y   Author
## 7    Qiu J   Author
## 8    Gao Z   Author
## 9    Fan Y   Author
## 10   Guo Q   Author
## 11   Qiu W   Author
## 12  Wang S   Author
## 13  Wang Q   Author
## 14 Zhang P   Author
## 15   Guo X   Author
## 16  Deng L   Author
## 17   Xue H   Author
## 18    Li G   Author
## 
## $result$`8924366`$title
## [1] "Comprehensive Analysis of the Tumor Immune Microenvironment Landscape in Glioblastoma Reveals Tumor Heterogeneity and Implications for Prognosis and Immunotherapy"
## 
## $result$`8924366`$volume
## [1] "13"
## 
## $result$`8924366`$issue
## [1] ""
## 
## $result$`8924366`$pages
## [1] "820673"
## 
## $result$`8924366`$articleids
##   idtype                     value
## 1   pmid                  35309323
## 2    doi 10.3389/fimmu.2022.820673
## 3  pmcid                PMC8924366
## 
## $result$`8924366`$fulljournalname
## [1] "Frontiers in Immunology"
## 
## $result$`8924366`$sortdate
## [1] "2022/03/02 00:00"
## 
## $result$`8924366`$pmclivedate
## [1] "2022/03/17"

Paper with most date conversions

MOST_ERR <- gsub("PMC","",MOST_ERR)
ARTICLE_DATA <- esummary(MOST_ERR,db = "pmc" , retmode = "json" )
ARTICLE_DATA <- reutils::content(ARTICLE_DATA,as= "parsed")
ARTICLE_DATA
## $header
## $header$type
## [1] "esummary"
## 
## $header$version
## [1] "0.3"
## 
## 
## $result
## $result$uids
## [1] "8885418"
## 
## $result$`8885418`
## $result$`8885418`$uid
## [1] "8885418"
## 
## $result$`8885418`$pubdate
## [1] "2021 Nov 5"
## 
## $result$`8885418`$epubdate
## [1] "2021 Nov 5"
## 
## $result$`8885418`$printpubdate
## [1] "2022"
## 
## $result$`8885418`$source
## [1] "Leukemia"
## 
## $result$`8885418`$authors
##                  name authtype
## 1          Stavast CJ   Author
## 2        van Zuijen I   Author
## 3         Karkoulia E   Author
## 4         Özçelik A   Author
## 5  van Hoven-Beijen A   Author
## 6             Leon LG   Author
## 7          Voerman JS   Author
## 8          Janssen GM   Author
## 9       van Veelen PA   Author
## 10       Burocziova M   Author
## 11         Brouwer RW   Author
## 12      van IJcken WF   Author
## 13             Maas A   Author
## 14         Bindels EM   Author
## 15  van der Velden VH   Author
## 16         Schliehe C   Author
## 17        Katsikis PD   Author
## 18   Alberich-Jorda M   Author
## 19        Erkeland SJ   Author
## 
## $result$`8885418`$title
## [1] "The tumor suppressor MIR139 is silenced by POLR2M to promote AML oncogenesis"
## 
## $result$`8885418`$volume
## [1] "36"
## 
## $result$`8885418`$issue
## [1] "3"
## 
## $result$`8885418`$pages
## [1] "687-700"
## 
## $result$`8885418`$articleids
##   idtype                      value
## 1   pmid                   34741119
## 2    doi 10.1038/s41375-021-01461-5
## 3  pmcid                 PMC8885418
## 
## $result$`8885418`$fulljournalname
## [1] "Leukemia"
## 
## $result$`8885418`$sortdate
## [1] "2021/11/05 00:00"
## 
## $result$`8885418`$pmclivedate
## [1] "2022/03/17"

Trend info

To plot the trend over the past 6-12 months.

url <- "http://ziemann-lab.net/public/gene_name_errors/"
doc <- htmlParse(url)
links <- xpathSApply(doc, "//a/@href")
links <- links[grep("html",links)]

links
##                  href                  href                  href 
## "Report_2021-02.html" "Report_2021-03.html" "Report_2021-04.html" 
##                  href                  href                  href 
## "Report_2021-05.html" "Report_2021-06.html" "Report_2021-07.html" 
##                  href                  href                  href 
## "Report_2021-08.html" "Report_2021-09.html" "Report_2021-10.html" 
##                  href                  href                  href 
## "Report_2021-11.html" "Report_2021-12.html" "Report_2022-01.html" 
##                  href                  href 
## "Report_2022-02.html" "Report_2022-03.html"
unlink("online_files/",recursive=TRUE)

dir.create("online_files")

sapply(links, function(mylink) { 
  download.file(paste(url,mylink,sep=""),destfile=paste("online_files/",mylink,sep=""))  
} )
## href href href href href href href href href href href href href href 
##    0    0    0    0    0    0    0    0    0    0    0    0    0    0
myfilelist <- list.files("online_files/",full.names=TRUE)

trends <- sapply(myfilelist,  function(myfilename) {

  x <- readLines(myfilename)

  # Num XL gene list articles
  NUM_GENELIST_ARTICLES <- x[grep("NUM_GENELIST_ARTICLES",x)[3]+1]
  NUM_GENELIST_ARTICLES <- sapply(strsplit(NUM_GENELIST_ARTICLES," "),"[[",3)
  NUM_GENELIST_ARTICLES <- sapply(strsplit(NUM_GENELIST_ARTICLES,"<"),"[[",1)
  NUM_GENELIST_ARTICLES <- as.numeric(NUM_GENELIST_ARTICLES)

  # number of affected articles
  NUM_ERROR_GENELIST_ARTICLES <- x[grep("NUM_ERROR_GENELIST_ARTICLES",x)[3]+1]
  NUM_ERROR_GENELIST_ARTICLES <- sapply(strsplit(NUM_ERROR_GENELIST_ARTICLES," "),"[[",3)
  NUM_ERROR_GENELIST_ARTICLES <- sapply(strsplit(NUM_ERROR_GENELIST_ARTICLES,"<"),"[[",1)
  NUM_ERROR_GENELIST_ARTICLES <- as.numeric(NUM_ERROR_GENELIST_ARTICLES)

  # Error proportion
  ERROR_PROPORTION <- x[grep("ERROR_PROPORTION",x)[3]+1]
  ERROR_PROPORTION <- sapply(strsplit(ERROR_PROPORTION," "),"[[",3)
  ERROR_PROPORTION <- sapply(strsplit(ERROR_PROPORTION,"<"),"[[",1)
  ERROR_PROPORTION <- as.numeric(ERROR_PROPORTION)

  # number of journals
  NUM_JOURNALS <- x[grep('JOURNALS_TABLE',x)[3]+1]
  NUM_JOURNALS <- sapply(strsplit(NUM_JOURNALS," "),"[[",3)
  NUM_JOURNALS <- sapply(strsplit(NUM_JOURNALS,"<"),"[[",1)
  NUM_JOURNALS <- as.numeric(NUM_JOURNALS)
  NUM_JOURNALS

  res <- c(NUM_GENELIST_ARTICLES,NUM_ERROR_GENELIST_ARTICLES,ERROR_PROPORTION,NUM_JOURNALS)

  return(res)
})

colnames(trends) <- sapply(strsplit(colnames(trends),"_"),"[[",3)
colnames(trends) <- gsub(".html","",colnames(trends))
trends <- as.data.frame(trends)
rownames(trends) <- c("NUM_GENELIST_ARTICLES","NUM_ERROR_GENELIST_ARTICLES","ERROR_PROPORTION","NUM_JOURNALS")
trends <- t(trends)
trends <- as.data.frame(trends)

CURRENT_RES <- c(NUM_GENELIST_ARTICLES,NUM_ERROR_GENELIST_ARTICLES,ERROR_PROPORTION,NUM_JOURNALS)

trends <- rbind(trends,CURRENT_RES)
paste(CURRENT_YEAR,CURRENT_MONTH,sep="-")
## [1] "2022-04"
rownames(trends)[nrow(trends)] <- paste(CURRENT_YEAR,CURRENT_MONTH,sep="-")

plot(trends$NUM_GENELIST_ARTICLES, xaxt = "n" , type="b" , main="Number of articles with Excel gene lists per month",
 ylab="number of articles", xlab="month")
axis(1, at=1:nrow(trends), labels=rownames(trends))

plot(trends$NUM_ERROR_GENELIST_ARTICLES, xaxt = "n" , type="b" , main="Number of articles with gene name errors per month",
 ylab="number of articles", xlab="month")
axis(1, at=1:nrow(trends), labels=rownames(trends))

plot(trends$ERROR_PROPORTION, xaxt = "n" , type="b" , main="Proportion of articles with Excel gene list affected by errors",
 ylab="proportion", xlab="month")
axis(1, at=1:nrow(trends), labels=rownames(trends))

plot(trends$NUM_JOURNALS, xaxt = "n" , type="b" , main="Number of journals with affected articles",
 ylab="number of journals", xlab="month")
axis(1, at=1:nrow(trends), labels=rownames(trends))

unlink("online_files/",recursive=TRUE)

References

  1. Zeeberg, B.R., Riss, J., Kane, D.W. et al. Mistaken Identifiers: Gene name errors can be introduced inadvertently when using Excel in bioinformatics. BMC Bioinformatics 5, 80 (2004). https://doi.org/10.1186/1471-2105-5-80

  2. Ziemann, M., Eren, Y. & El-Osta, A. Gene name errors are widespread in the scientific literature. Genome Biol 17, 177 (2016). https://doi.org/10.1186/s13059-016-1044-7

SessionInfo

sessionInfo()
## R version 4.1.3 (2022-03-10)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 20.04.4 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.9.0
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.9.0
## 
## locale:
##  [1] LC_CTYPE=en_AU.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_AU.UTF-8        LC_COLLATE=en_AU.UTF-8    
##  [5] LC_MONETARY=en_AU.UTF-8    LC_MESSAGES=en_AU.UTF-8   
##  [7] LC_PAPER=en_AU.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_AU.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
## [1] stats     graphics  grDevices utils     datasets  methods   base     
## 
## other attached packages:
## [1] readxl_1.3.1   reutils_0.2.3  xml2_1.3.3     jsonlite_1.8.0 XML_3.99-0.9  
## 
## loaded via a namespace (and not attached):
##  [1] Rcpp_1.0.8.3     knitr_1.37       magrittr_2.0.2   R6_2.5.1        
##  [5] rlang_1.0.2      fastmap_1.1.0    highr_0.9        stringr_1.4.0   
##  [9] tools_4.1.3      xfun_0.30        cli_3.2.0        jquerylib_0.1.4 
## [13] htmltools_0.5.2  yaml_2.3.5       digest_0.6.29    assertthat_0.2.1
## [17] sass_0.4.1       bitops_1.0-7     RCurl_1.98-1.6   evaluate_0.15   
## [21] rmarkdown_2.13   stringi_1.7.6    compiler_4.1.3   bslib_0.3.1     
## [25] cellranger_1.1.0