date generated: 2024-01-04

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch
Estill Novakovic
A1BG -2.7341135 -0.7186568
A1BG-AS1 -2.9086004 -0.1813097
A1CF -1.4455477 -0.5404743
A2M 0.1755092 -0.4595169
A2ML1 1.1420743 -0.4082271
A4GALT -1.2155001 -0.5418459

Here are some metrics about the input data profile:

Profiling data metrics
Profile metrics
num_genes_in_profile 19234
duplicated_genes_present 0
num_profile_genes_in_sets 10289
num_profile_genes_not_in_sets 8945
profile_pearson_correl 0.23938
profile_spearman_correl 0.2567

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt
Gene set metrics
Gene sets metrics
num_genesets 1654
num_genesets_excluded 365
num_genesets_included 1289

Gene sets by quadrant


Number of significant gene sets (FDR<0.05)= 200

Interactive enrichment scatterplot

All sets with FDR<0.05. Try hovering over the points.

Top N sets irrespective of FDR. Try hovering over the points.

A heatmap of S values for top results


A plot of effect size versus significance


Significance is the -log2(p.adjustMANOVA) and effect size is the s.dist which is the hypotenuse of the s scores.

Results table

Top N= 50 gene sets

## Warning in kable_styling(., "hover", full_width = FALSE): Please specify format
## in kable. kableExtra can customize either HTML or LaTeX outputs. See
## https://haozhu233.github.io/kableExtra/ for details.
set setSize pMANOVA p.adjustMANOVA s.dist s.Estill s.Novakovic p.Estill p.Novakovic
REACTOME OLFACTORY SIGNALING PATHWAY 313 1.53e-48 2.51e-45 0.533 0.46300 0.2650 3.58e-45 8.15e-16
REACTOME SENSORY PERCEPTION 512 2.82e-32 2.32e-29 0.347 0.27500 0.2110 1.53e-26 3.48e-16
REACTOME KERATINIZATION 198 3.18e-21 1.74e-18 0.449 0.31600 0.3180 1.60e-14 1.19e-14
REACTOME RNA POLYMERASE II TRANSCRIPTION 1329 1.64e-20 6.75e-18 0.172 -0.08980 -0.1470 4.41e-08 3.25e-19
REACTOME TRANSLATION 280 2.04e-19 6.71e-17 0.323 -0.04690 -0.3200 1.77e-01 3.04e-20
REACTOME METABOLISM OF RNA 673 6.18e-18 1.69e-15 0.210 -0.06030 -0.2010 7.74e-03 5.92e-19
REACTOME FORMATION OF THE CORNIFIED ENVELOPE 123 9.21e-16 2.16e-13 0.474 0.22800 0.4160 1.26e-05 1.65e-15
REACTOME ANTIMICROBIAL PEPTIDES 81 1.20e-14 2.46e-12 0.565 0.29000 0.4850 6.64e-06 4.28e-14
REACTOME CELL CYCLE 667 1.64e-13 2.99e-11 0.191 -0.09270 -0.1670 4.61e-05 2.32e-13
REACTOME CELLULAR RESPONSES TO STIMULI 781 1.05e-12 1.72e-10 0.174 -0.10500 -0.1390 5.86e-07 4.32e-11
REACTOME CELL CYCLE MITOTIC 540 2.10e-11 3.14e-09 0.194 -0.09660 -0.1680 1.26e-04 2.78e-11
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION 1346 3.26e-09 4.46e-07 0.113 -0.06690 -0.0916 4.15e-05 1.99e-08
REACTOME M PHASE 399 4.22e-09 5.02e-07 0.199 -0.10200 -0.1710 4.58e-04 4.80e-09
REACTOME INFECTIOUS DISEASE 908 4.28e-09 5.02e-07 0.136 -0.08200 -0.1080 2.93e-05 3.62e-08
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA 261 1.42e-08 1.55e-06 0.227 -0.06910 -0.2160 5.49e-02 1.98e-09
REACTOME DEFENSINS 41 2.56e-08 2.55e-06 0.592 0.34100 0.4840 1.61e-04 8.00e-08
REACTOME CELL CYCLE CHECKPOINTS 284 2.88e-08 2.55e-06 0.215 -0.07300 -0.2020 3.45e-02 4.66e-09
REACTOME INFLUENZA INFECTION 150 2.90e-08 2.55e-06 0.299 -0.12100 -0.2740 1.04e-02 7.25e-09
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 162 2.95e-08 2.55e-06 0.260 -0.00456 -0.2600 9.20e-01 1.09e-08
REACTOME DNA REPAIR 323 5.12e-08 4.20e-06 0.205 -0.09930 -0.1790 2.17e-03 3.05e-08
REACTOME BETA DEFENSINS 32 1.11e-07 8.70e-06 0.648 0.44700 0.4680 1.18e-05 4.53e-06
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS 111 1.67e-07 1.25e-05 0.321 -0.09410 -0.3070 8.69e-02 2.41e-08
REACTOME HIV INFECTION 223 1.89e-07 1.35e-05 0.228 -0.07410 -0.2150 5.69e-02 2.99e-08
REACTOME MITOCHONDRIAL PROTEIN IMPORT 58 2.75e-07 1.82e-05 0.402 0.00551 -0.4020 9.42e-01 1.20e-07
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 106 2.77e-07 1.82e-05 0.314 -0.06120 -0.3080 2.77e-01 4.12e-08
REACTOME EUKARYOTIC TRANSLATION INITIATION 112 3.23e-07 2.04e-05 0.290 -0.00246 -0.2900 9.64e-01 1.19e-07
REACTOME HIV LIFE CYCLE 145 3.59e-07 2.14e-05 0.287 -0.14400 -0.2490 2.77e-03 2.37e-07
REACTOME TRANSCRIPTIONAL REGULATION BY TP53 351 3.71e-07 2.14e-05 0.188 -0.11300 -0.1510 2.84e-04 1.24e-06
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL 121 3.77e-07 2.14e-05 0.313 0.15300 0.2730 3.76e-03 2.08e-07
REACTOME COMPLEMENT CASCADE 54 4.49e-07 2.46e-05 0.467 0.23600 0.4020 2.70e-03 3.10e-07
REACTOME MITOCHONDRIAL TRANSLATION 93 7.14e-07 3.78e-05 0.325 -0.06520 -0.3190 2.77e-01 1.08e-07
REACTOME TRNA PROCESSING 105 7.56e-07 3.88e-05 0.312 -0.08720 -0.3000 1.23e-01 1.12e-07
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT 159 7.84e-07 3.90e-05 0.264 -0.11500 -0.2370 1.20e-02 2.50e-07
REACTOME SIGNALING BY ROBO RECEPTORS 207 2.93e-06 1.42e-04 0.202 -0.01910 -0.2010 6.35e-01 6.39e-07
REACTOME RRNA PROCESSING 193 3.16e-06 1.48e-04 0.217 -0.05320 -0.2100 2.03e-01 4.83e-07
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT 222 3.57e-06 1.63e-04 0.213 -0.10300 -0.1870 8.22e-03 1.67e-06
REACTOME NONSENSE MEDIATED DECAY NMD 108 4.71e-06 2.09e-04 0.276 -0.03570 -0.2740 5.22e-01 9.06e-07
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS 101 7.89e-06 3.41e-04 0.303 -0.13700 -0.2700 1.72e-02 2.71e-06
REACTOME CELLULAR RESPONSE TO STARVATION 148 8.45e-06 3.56e-04 0.241 -0.07130 -0.2300 1.34e-01 1.39e-06
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION 294 9.44e-06 3.88e-04 0.180 -0.09480 -0.1530 5.22e-03 6.73e-06
REACTOME EUKARYOTIC TRANSLATION ELONGATION 88 1.09e-05 4.31e-04 0.293 -0.03170 -0.2910 6.08e-01 2.30e-06
REACTOME RESPIRATORY ELECTRON TRANSPORT 90 1.13e-05 4.31e-04 0.294 -0.04900 -0.2900 4.21e-01 1.99e-06
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM 78 1.13e-05 4.31e-04 0.346 -0.19000 -0.2890 3.66e-03 1.06e-05
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS 113 1.22e-05 4.54e-04 0.277 -0.10700 -0.2550 4.91e-02 2.72e-06
REACTOME NEDDYLATION 233 1.24e-05 4.54e-04 0.190 -0.06070 -0.1800 1.10e-01 2.18e-06
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL 130 1.82e-05 6.51e-04 0.245 0.06030 0.2370 2.35e-01 2.99e-06
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION 145 1.90e-05 6.63e-04 0.241 -0.09820 -0.2200 4.13e-02 4.73e-06
REACTOME MITOTIC PROMETAPHASE 194 2.02e-05 6.84e-04 0.204 -0.06630 -0.1930 1.12e-01 3.64e-06
REACTOME MITOTIC METAPHASE AND ANAPHASE 228 2.07e-05 6.84e-04 0.189 -0.06360 -0.1780 9.83e-02 3.86e-06
REACTOME DNA REPLICATION 179 2.12e-05 6.84e-04 0.213 -0.07420 -0.2000 8.71e-02 4.09e-06


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pMANOVA p.adjustMANOVA s.dist s.Estill s.Novakovic p.Estill p.Novakovic
REACTOME OLFACTORY SIGNALING PATHWAY 313 1.53e-48 2.51e-45 0.53300 0.463000 0.265000 3.58e-45 8.15e-16
REACTOME SENSORY PERCEPTION 512 2.82e-32 2.32e-29 0.34700 0.275000 0.211000 1.53e-26 3.48e-16
REACTOME KERATINIZATION 198 3.18e-21 1.74e-18 0.44900 0.316000 0.318000 1.60e-14 1.19e-14
REACTOME RNA POLYMERASE II TRANSCRIPTION 1329 1.64e-20 6.75e-18 0.17200 -0.089800 -0.147000 4.41e-08 3.25e-19
REACTOME TRANSLATION 280 2.04e-19 6.71e-17 0.32300 -0.046900 -0.320000 1.77e-01 3.04e-20
REACTOME METABOLISM OF RNA 673 6.18e-18 1.69e-15 0.21000 -0.060300 -0.201000 7.74e-03 5.92e-19
REACTOME FORMATION OF THE CORNIFIED ENVELOPE 123 9.21e-16 2.16e-13 0.47400 0.228000 0.416000 1.26e-05 1.65e-15
REACTOME ANTIMICROBIAL PEPTIDES 81 1.20e-14 2.46e-12 0.56500 0.290000 0.485000 6.64e-06 4.28e-14
REACTOME CELL CYCLE 667 1.64e-13 2.99e-11 0.19100 -0.092700 -0.167000 4.61e-05 2.32e-13
REACTOME CELLULAR RESPONSES TO STIMULI 781 1.05e-12 1.72e-10 0.17400 -0.105000 -0.139000 5.86e-07 4.32e-11
REACTOME CELL CYCLE MITOTIC 540 2.10e-11 3.14e-09 0.19400 -0.096600 -0.168000 1.26e-04 2.78e-11
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION 1346 3.26e-09 4.46e-07 0.11300 -0.066900 -0.091600 4.15e-05 1.99e-08
REACTOME M PHASE 399 4.22e-09 5.02e-07 0.19900 -0.102000 -0.171000 4.58e-04 4.80e-09
REACTOME INFECTIOUS DISEASE 908 4.28e-09 5.02e-07 0.13600 -0.082000 -0.108000 2.93e-05 3.62e-08
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA 261 1.42e-08 1.55e-06 0.22700 -0.069100 -0.216000 5.49e-02 1.98e-09
REACTOME DEFENSINS 41 2.56e-08 2.55e-06 0.59200 0.341000 0.484000 1.61e-04 8.00e-08
REACTOME CELL CYCLE CHECKPOINTS 284 2.88e-08 2.55e-06 0.21500 -0.073000 -0.202000 3.45e-02 4.66e-09
REACTOME INFLUENZA INFECTION 150 2.90e-08 2.55e-06 0.29900 -0.121000 -0.274000 1.04e-02 7.25e-09
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 162 2.95e-08 2.55e-06 0.26000 -0.004560 -0.260000 9.20e-01 1.09e-08
REACTOME DNA REPAIR 323 5.12e-08 4.20e-06 0.20500 -0.099300 -0.179000 2.17e-03 3.05e-08
REACTOME BETA DEFENSINS 32 1.11e-07 8.70e-06 0.64800 0.447000 0.468000 1.18e-05 4.53e-06
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS 111 1.67e-07 1.25e-05 0.32100 -0.094100 -0.307000 8.69e-02 2.41e-08
REACTOME HIV INFECTION 223 1.89e-07 1.35e-05 0.22800 -0.074100 -0.215000 5.69e-02 2.99e-08
REACTOME MITOCHONDRIAL PROTEIN IMPORT 58 2.75e-07 1.82e-05 0.40200 0.005510 -0.402000 9.42e-01 1.20e-07
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 106 2.77e-07 1.82e-05 0.31400 -0.061200 -0.308000 2.77e-01 4.12e-08
REACTOME EUKARYOTIC TRANSLATION INITIATION 112 3.23e-07 2.04e-05 0.29000 -0.002460 -0.290000 9.64e-01 1.19e-07
REACTOME HIV LIFE CYCLE 145 3.59e-07 2.14e-05 0.28700 -0.144000 -0.249000 2.77e-03 2.37e-07
REACTOME TRANSCRIPTIONAL REGULATION BY TP53 351 3.71e-07 2.14e-05 0.18800 -0.113000 -0.151000 2.84e-04 1.24e-06
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL 121 3.77e-07 2.14e-05 0.31300 0.153000 0.273000 3.76e-03 2.08e-07
REACTOME COMPLEMENT CASCADE 54 4.49e-07 2.46e-05 0.46700 0.236000 0.402000 2.70e-03 3.10e-07
REACTOME MITOCHONDRIAL TRANSLATION 93 7.14e-07 3.78e-05 0.32500 -0.065200 -0.319000 2.77e-01 1.08e-07
REACTOME TRNA PROCESSING 105 7.56e-07 3.88e-05 0.31200 -0.087200 -0.300000 1.23e-01 1.12e-07
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT 159 7.84e-07 3.90e-05 0.26400 -0.115000 -0.237000 1.20e-02 2.50e-07
REACTOME SIGNALING BY ROBO RECEPTORS 207 2.93e-06 1.42e-04 0.20200 -0.019100 -0.201000 6.35e-01 6.39e-07
REACTOME RRNA PROCESSING 193 3.16e-06 1.48e-04 0.21700 -0.053200 -0.210000 2.03e-01 4.83e-07
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT 222 3.57e-06 1.63e-04 0.21300 -0.103000 -0.187000 8.22e-03 1.67e-06
REACTOME NONSENSE MEDIATED DECAY NMD 108 4.71e-06 2.09e-04 0.27600 -0.035700 -0.274000 5.22e-01 9.06e-07
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS 101 7.89e-06 3.41e-04 0.30300 -0.137000 -0.270000 1.72e-02 2.71e-06
REACTOME CELLULAR RESPONSE TO STARVATION 148 8.45e-06 3.56e-04 0.24100 -0.071300 -0.230000 1.34e-01 1.39e-06
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION 294 9.44e-06 3.88e-04 0.18000 -0.094800 -0.153000 5.22e-03 6.73e-06
REACTOME EUKARYOTIC TRANSLATION ELONGATION 88 1.09e-05 4.31e-04 0.29300 -0.031700 -0.291000 6.08e-01 2.30e-06
REACTOME RESPIRATORY ELECTRON TRANSPORT 90 1.13e-05 4.31e-04 0.29400 -0.049000 -0.290000 4.21e-01 1.99e-06
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM 78 1.13e-05 4.31e-04 0.34600 -0.190000 -0.289000 3.66e-03 1.06e-05
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS 113 1.22e-05 4.54e-04 0.27700 -0.107000 -0.255000 4.91e-02 2.72e-06
REACTOME NEDDYLATION 233 1.24e-05 4.54e-04 0.19000 -0.060700 -0.180000 1.10e-01 2.18e-06
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL 130 1.82e-05 6.51e-04 0.24500 0.060300 0.237000 2.35e-01 2.99e-06
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION 145 1.90e-05 6.63e-04 0.24100 -0.098200 -0.220000 4.13e-02 4.73e-06
REACTOME MITOTIC PROMETAPHASE 194 2.02e-05 6.84e-04 0.20400 -0.066300 -0.193000 1.12e-01 3.64e-06
REACTOME MITOTIC METAPHASE AND ANAPHASE 228 2.07e-05 6.84e-04 0.18900 -0.063600 -0.178000 9.83e-02 3.86e-06
REACTOME DNA REPLICATION 179 2.12e-05 6.84e-04 0.21300 -0.074200 -0.200000 8.71e-02 4.09e-06
REACTOME DEUBIQUITINATION 262 2.12e-05 6.84e-04 0.18400 -0.101000 -0.154000 5.00e-03 1.79e-05
REACTOME TRNA PROCESSING IN THE NUCLEUS 58 2.25e-05 7.09e-04 0.38600 -0.198000 -0.331000 9.16e-03 1.28e-05
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE 277 2.35e-05 7.27e-04 0.17600 -0.082800 -0.155000 1.78e-02 9.06e-06
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION 141 2.39e-05 7.28e-04 0.24300 -0.105000 -0.219000 3.09e-02 6.98e-06
REACTOME INNATE IMMUNE SYSTEM 997 2.51e-05 7.50e-04 0.08610 0.010200 0.085500 5.88e-01 5.20e-06
REACTOME CHROMATIN MODIFYING ENZYMES 252 3.17e-05 9.29e-04 0.17700 -0.061700 -0.165000 9.19e-02 6.21e-06
REACTOME MRNA SPLICING 195 3.47e-05 1.00e-03 0.19200 -0.038500 -0.188000 3.54e-01 6.03e-06
REACTOME GENERATION OF SECOND MESSENGER MOLECULES 30 3.85e-05 1.09e-03 0.53300 0.386000 0.368000 2.54e-04 4.90e-04
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION 59 4.07e-05 1.13e-03 0.37900 -0.262000 -0.274000 5.05e-04 2.66e-04
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY 95 4.15e-05 1.13e-03 0.27200 -0.057100 -0.266000 3.37e-01 7.19e-06
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES 77 4.51e-05 1.21e-03 0.30300 -0.068000 -0.295000 3.02e-01 7.74e-06
REACTOME UB SPECIFIC PROCESSING PROTEASES 189 4.73e-05 1.25e-03 0.20800 -0.114000 -0.174000 6.84e-03 3.71e-05
REACTOME SEPARATION OF SISTER CHROMATIDS 184 5.37e-05 1.40e-03 0.18900 -0.021400 -0.188000 6.17e-01 1.15e-05
REACTOME SELENOAMINO ACID METABOLISM 110 5.51e-05 1.41e-03 0.23500 0.005800 -0.235000 9.16e-01 2.12e-05
REACTOME DNA REPLICATION PRE INITIATION 151 5.82e-05 1.47e-03 0.22000 -0.075200 -0.207000 1.11e-01 1.14e-05
REACTOME SIGNALING BY WNT 318 6.25e-05 1.56e-03 0.15800 -0.081200 -0.135000 1.29e-02 3.38e-05
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS 122 6.80e-05 1.65e-03 0.24500 -0.092700 -0.227000 7.70e-02 1.51e-05
REACTOME PD 1 SIGNALING 21 6.85e-05 1.65e-03 0.61700 0.475000 0.393000 1.62e-04 1.82e-03
REACTOME G2 M CHECKPOINTS 162 6.96e-05 1.65e-03 0.21100 -0.070900 -0.198000 1.20e-01 1.35e-05
REACTOME CHROMOSOME MAINTENANCE 130 7.03e-05 1.65e-03 0.23200 -0.068700 -0.222000 1.77e-01 1.26e-05
REACTOME CELLULAR SENESCENCE 188 7.41e-05 1.71e-03 0.20600 -0.161000 -0.129000 1.48e-04 2.27e-03
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION 363 7.92e-05 1.81e-03 0.14500 -0.071400 -0.127000 1.96e-02 3.44e-05
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION 62 1.07e-04 2.41e-03 0.33800 -0.140000 -0.307000 5.58e-02 2.83e-05
REACTOME MEMBRANE TRAFFICKING 601 1.09e-04 2.42e-03 0.11300 -0.092500 -0.065600 1.10e-04 6.10e-03
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS 415 1.11e-04 2.42e-03 0.13300 -0.063300 -0.117000 2.73e-02 4.18e-05
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS 77 1.19e-04 2.56e-03 0.28300 -0.048600 -0.279000 4.61e-01 2.27e-05
REACTOME MITOTIC PROPHASE 135 1.33e-04 2.83e-03 0.23600 -0.168000 -0.166000 7.76e-04 8.45e-04
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 101 1.34e-04 2.83e-03 0.26800 -0.139000 -0.228000 1.57e-02 7.27e-05
REACTOME TRANSCRIPTION OF THE HIV GENOME 66 1.40e-04 2.90e-03 0.30200 -0.048100 -0.298000 4.99e-01 2.76e-05
REACTOME INTERLEUKIN 10 SIGNALING 44 1.41e-04 2.90e-03 0.40700 0.333000 0.234000 1.31e-04 7.29e-03
REACTOME NGF STIMULATED TRANSCRIPTION 38 1.48e-04 3.00e-03 0.43900 -0.268000 -0.348000 4.28e-03 2.09e-04
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 59 1.56e-04 3.12e-03 0.30300 0.004540 -0.303000 9.52e-01 5.55e-05
REACTOME ESR MEDIATED SIGNALING 209 1.83e-04 3.63e-03 0.18400 -0.097500 -0.156000 1.51e-02 1.07e-04
REACTOME CRISTAE FORMATION 27 2.04e-04 3.99e-03 0.50900 -0.295000 -0.415000 8.01e-03 1.91e-04
REACTOME PROTEIN LOCALIZATION 153 2.41e-04 4.63e-03 0.20700 -0.089900 -0.186000 5.51e-02 7.05e-05
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT 236 2.43e-04 4.63e-03 0.13300 -0.094200 0.093900 1.28e-02 1.30e-02
REACTOME RHO GTPASES ACTIVATE FORMINS 136 2.99e-04 5.65e-03 0.20200 -0.032200 -0.199000 5.17e-01 6.09e-05
REACTOME HCMV LATE EVENTS 112 3.66e-04 6.83e-03 0.24400 -0.166000 -0.179000 2.44e-03 1.08e-03
REACTOME RESOLUTION OF SISTER CHROMATID COHESION 120 3.73e-04 6.88e-03 0.21000 -0.026300 -0.208000 6.19e-01 8.22e-05
REACTOME HOST INTERACTIONS OF HIV FACTORS 127 4.08e-04 7.31e-03 0.20800 -0.044400 -0.203000 3.88e-01 7.90e-05
REACTOME S PHASE 159 4.17e-04 7.31e-03 0.19400 -0.076900 -0.178000 9.46e-02 1.03e-04
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS 84 4.19e-04 7.31e-03 0.27800 -0.179000 -0.213000 4.56e-03 7.34e-04
REACTOME ASPIRIN ADME 36 4.20e-04 7.31e-03 0.42200 0.343000 0.245000 3.64e-04 1.09e-02
REACTOME MITOCHONDRIAL BIOGENESIS 87 4.21e-04 7.31e-03 0.27400 -0.188000 -0.200000 2.48e-03 1.29e-03
REACTOME SIGNALING BY NOTCH4 80 4.23e-04 7.31e-03 0.23800 0.032300 -0.236000 6.17e-01 2.62e-04
REACTOME RMTS METHYLATE HISTONE ARGININES 73 4.28e-04 7.31e-03 0.27600 -0.073100 -0.267000 2.80e-01 8.21e-05
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY 84 4.49e-04 7.60e-03 0.25100 -0.046000 -0.247000 4.66e-01 9.00e-05
REACTOME GENE SILENCING BY RNA 134 4.66e-04 7.81e-03 0.20900 -0.076700 -0.194000 1.25e-01 1.06e-04
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE 118 4.91e-04 8.08e-03 0.23300 -0.170000 -0.159000 1.40e-03 2.80e-03
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES 54 4.92e-04 8.08e-03 0.34200 0.273000 0.206000 5.21e-04 8.86e-03
REACTOME HATS ACETYLATE HISTONES 131 5.04e-04 8.20e-03 0.20500 -0.057000 -0.197000 2.60e-01 9.84e-05
REACTOME INITIAL TRIGGERING OF COMPLEMENT 21 5.37e-04 8.65e-03 0.49400 0.080400 0.487000 5.23e-01 1.12e-04
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX 57 5.57e-04 8.75e-03 0.29900 -0.049600 -0.295000 5.17e-01 1.16e-04
REACTOME ORC1 REMOVAL FROM CHROMATIN 70 5.59e-04 8.75e-03 0.26100 -0.010500 -0.261000 8.79e-01 1.59e-04
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA 28 5.59e-04 8.75e-03 0.41700 -0.032800 -0.416000 7.64e-01 1.41e-04
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2 117 5.74e-04 8.90e-03 0.22400 -0.101000 -0.200000 5.97e-02 1.81e-04
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS 43 6.05e-04 9.28e-03 0.37100 -0.180000 -0.324000 4.17e-02 2.33e-04
REACTOME RNA POLYMERASE I PROMOTER ESCAPE 84 6.87e-04 1.04e-02 0.26300 -0.128000 -0.230000 4.20e-02 2.69e-04
REACTOME MITOTIC SPINDLE CHECKPOINT 109 7.19e-04 1.08e-02 0.21400 -0.037400 -0.210000 5.00e-01 1.49e-04
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION 61 7.44e-04 1.11e-02 0.30900 -0.157000 -0.265000 3.34e-02 3.38e-04
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS 35 7.56e-04 1.12e-02 0.41200 -0.248000 -0.329000 1.11e-02 7.47e-04
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES 355 8.25e-04 1.21e-02 0.11400 -0.004380 -0.114000 8.87e-01 2.37e-04
REACTOME MITOTIC G2 G2 M PHASES 194 8.39e-04 1.22e-02 0.15600 -0.017300 -0.155000 6.78e-01 1.97e-04
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP 104 8.60e-04 1.24e-02 0.23700 -0.192000 -0.139000 7.09e-04 1.46e-02
REACTOME VIRAL MESSENGER RNA SYNTHESIS 44 8.65e-04 1.24e-02 0.35400 -0.154000 -0.319000 7.81e-02 2.54e-04
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES 38 9.68e-04 1.36e-02 0.31400 -0.298000 0.099900 1.49e-03 2.86e-01
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION 139 9.76e-04 1.36e-02 0.20500 -0.138000 -0.151000 4.89e-03 2.08e-03
REACTOME SIGNALING BY NOTCH 235 9.85e-04 1.36e-02 0.14300 -0.025100 -0.141000 5.07e-01 2.08e-04
REACTOME SIGNALING BY NUCLEAR RECEPTORS 280 9.86e-04 1.36e-02 0.14300 -0.078000 -0.120000 2.49e-02 5.71e-04
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS 63 1.01e-03 1.39e-02 0.27100 -0.038100 -0.269000 6.01e-01 2.27e-04
REACTOME MICRORNA MIRNA BIOGENESIS 25 1.09e-03 1.48e-02 0.43100 -0.072800 -0.425000 5.29e-01 2.34e-04
REACTOME RHO GTPASE EFFECTORS 307 1.20e-03 1.62e-02 0.13500 -0.079700 -0.110000 1.65e-02 9.77e-04
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION 85 1.22e-03 1.62e-02 0.25200 -0.123000 -0.219000 4.91e-02 4.80e-04
REACTOME AMINO ACID CONJUGATION 8 1.30e-03 1.72e-02 0.81400 0.710000 0.398000 5.03e-04 5.14e-02
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS 82 1.36e-03 1.78e-02 0.20100 -0.115000 0.165000 7.17e-02 9.68e-03
REACTOME ASPARAGINE N LINKED GLYCOSYLATION 299 1.37e-03 1.78e-02 0.13600 -0.082600 -0.108000 1.41e-02 1.29e-03
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS 189 1.45e-03 1.87e-02 0.16800 -0.091400 -0.142000 3.03e-02 7.97e-04
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 227 1.46e-03 1.88e-02 0.15300 -0.075700 -0.132000 4.96e-02 5.91e-04
REACTOME DECTIN 2 FAMILY 23 1.52e-03 1.91e-02 0.46200 0.169000 0.430000 1.61e-01 3.60e-04
REACTOME METABOLISM OF POLYAMINES 56 1.52e-03 1.91e-02 0.26500 0.016500 -0.264000 8.31e-01 6.23e-04
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING 53 1.54e-03 1.91e-02 0.26900 0.030400 -0.267000 7.02e-01 7.80e-04
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS 99 1.56e-03 1.91e-02 0.18700 -0.063100 0.177000 2.78e-01 2.41e-03
REACTOME HIV TRANSCRIPTION ELONGATION 42 1.57e-03 1.91e-02 0.31400 -0.018300 -0.314000 8.37e-01 4.32e-04
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES 61 1.58e-03 1.91e-02 0.26400 -0.027100 -0.263000 7.14e-01 3.88e-04
REACTOME HDMS DEMETHYLATE HISTONES 41 1.58e-03 1.91e-02 0.30500 0.033300 -0.303000 7.12e-01 7.84e-04
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION 63 1.59e-03 1.91e-02 0.29000 -0.163000 -0.240000 2.54e-02 1.01e-03
REACTOME TP53 REGULATES METABOLIC GENES 81 1.60e-03 1.91e-02 0.25800 -0.164000 -0.199000 1.09e-02 1.94e-03
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING 16 1.63e-03 1.94e-02 0.57600 -0.347000 -0.460000 1.63e-02 1.45e-03
REACTOME MUSCLE CONTRACTION 197 1.67e-03 1.98e-02 0.12800 -0.097600 0.082300 1.82e-02 4.67e-02
REACTOME STRIATED MUSCLE CONTRACTION 35 1.76e-03 2.07e-02 0.30000 -0.213000 0.211000 2.92e-02 3.06e-02
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER 81 1.85e-03 2.16e-02 0.24800 -0.219000 -0.116000 6.40e-04 7.09e-02
REACTOME TELOMERE MAINTENANCE 106 2.02e-03 2.33e-02 0.20800 -0.064900 -0.198000 2.48e-01 4.43e-04
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX 83 2.08e-03 2.39e-02 0.22900 -0.052100 -0.223000 4.12e-01 4.43e-04
REACTOME DISEASES OF PROGRAMMED CELL DEATH 96 2.13e-03 2.43e-02 0.22700 -0.111000 -0.198000 6.10e-02 8.16e-04
REACTOME NUCLEOTIDE EXCISION REPAIR 107 2.26e-03 2.50e-02 0.21900 -0.146000 -0.163000 9.14e-03 3.59e-03
REACTOME VESICLE MEDIATED TRANSPORT 638 2.27e-03 2.50e-02 0.08920 -0.076200 -0.046400 1.04e-03 4.59e-02
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S 55 2.27e-03 2.50e-02 0.25200 0.044600 -0.248000 5.68e-01 1.47e-03
REACTOME APOPTOSIS 173 2.27e-03 2.50e-02 0.17200 -0.127000 -0.117000 4.09e-03 7.98e-03
REACTOME VISUAL PHOTOTRANSDUCTION 93 2.28e-03 2.50e-02 0.22700 0.099400 0.204000 9.75e-02 6.94e-04
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES 80 2.29e-03 2.50e-02 0.25300 -0.188000 -0.169000 3.70e-03 9.00e-03
REACTOME PROCESSING OF INTRONLESS PRE MRNAS 19 2.30e-03 2.50e-02 0.44900 -0.011700 -0.449000 9.30e-01 6.99e-04
REACTOME HIV ELONGATION ARREST AND RECOVERY 33 2.49e-03 2.69e-02 0.34400 -0.028000 -0.343000 7.81e-01 6.55e-04
REACTOME SARS COV INFECTIONS 387 2.50e-03 2.69e-02 0.11400 -0.089900 -0.070900 2.42e-03 1.68e-02
REACTOME DNA DOUBLE STRAND BREAK REPAIR 164 2.54e-03 2.71e-02 0.17200 -0.086700 -0.148000 5.55e-02 1.06e-03
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS 122 2.73e-03 2.90e-02 0.16900 -0.168000 0.020000 1.36e-03 7.03e-01
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS 60 2.77e-03 2.92e-02 0.24500 0.010400 -0.245000 8.89e-01 1.05e-03
REACTOME HEDGEHOG LIGAND BIOGENESIS 64 2.80e-03 2.93e-02 0.24800 -0.030900 -0.246000 6.69e-01 6.80e-04
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS 68 2.83e-03 2.94e-02 0.26400 -0.138000 -0.226000 4.92e-02 1.30e-03
REACTOME NEURONAL SYSTEM 386 2.89e-03 2.99e-02 0.08810 -0.049400 0.073000 9.61e-02 1.39e-02
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT 23 2.97e-03 3.04e-02 0.41400 -0.064000 -0.409000 5.95e-01 6.90e-04
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX 32 2.98e-03 3.04e-02 0.35100 -0.054100 -0.346000 5.96e-01 6.93e-04
REACTOME SARS COV 2 INFECTION 275 3.11e-03 3.15e-02 0.13300 -0.089800 -0.098700 1.04e-02 4.86e-03
REACTOME MRNA CAPPING 28 3.16e-03 3.18e-02 0.38200 -0.092900 -0.370000 3.95e-01 6.90e-04
REACTOME MRNA SPLICING MINOR PATHWAY 48 3.37e-03 3.37e-02 0.29500 -0.090500 -0.281000 2.78e-01 7.61e-04
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS 38 3.45e-03 3.43e-02 0.34400 -0.163000 -0.303000 8.29e-02 1.22e-03
REACTOME CELLULAR RESPONSE TO HYPOXIA 74 3.54e-03 3.49e-02 0.22200 -0.012600 -0.221000 8.52e-01 1.00e-03
REACTOME DISEASES OF DNA REPAIR 51 3.55e-03 3.49e-02 0.29300 -0.122000 -0.266000 1.33e-01 1.01e-03
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA 36 3.59e-03 3.51e-02 0.35800 -0.198000 -0.297000 3.93e-02 2.01e-03
REACTOME TRNA AMINOACYLATION 40 3.67e-03 3.56e-02 0.29600 -0.000404 -0.296000 9.96e-01 1.20e-03
REACTOME METABOLISM OF LIPIDS 702 3.74e-03 3.61e-02 0.07770 -0.074100 -0.023700 8.48e-04 2.87e-01
REACTOME HIV TRANSCRIPTION INITIATION 43 3.75e-03 3.61e-02 0.29600 -0.044100 -0.293000 6.17e-01 8.93e-04
REACTOME HCMV INFECTION 154 3.80e-03 3.63e-02 0.17500 -0.121000 -0.126000 9.69e-03 6.86e-03
REACTOME SARS COV 2 HOST INTERACTIONS 185 3.90e-03 3.68e-02 0.15700 -0.085600 -0.132000 4.48e-02 2.04e-03
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS 41 3.90e-03 3.68e-02 0.33700 -0.243000 -0.234000 7.19e-03 9.60e-03
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES 15 3.95e-03 3.71e-02 0.55500 -0.362000 -0.421000 1.51e-02 4.80e-03
REACTOME MRNA EDITING C TO U CONVERSION 8 4.14e-03 3.87e-02 0.75500 0.473000 0.589000 2.06e-02 3.94e-03
REACTOME PHOSPHOLIPID METABOLISM 199 4.23e-03 3.93e-02 0.12200 -0.115000 0.041200 5.31e-03 3.17e-01
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS 33 4.32e-03 3.98e-02 0.37000 -0.222000 -0.295000 2.72e-02 3.32e-03
REACTOME DEGRADATION OF AXIN 54 4.34e-03 3.98e-02 0.25300 -0.008990 -0.253000 9.09e-01 1.30e-03
REACTOME FGFR2 ALTERNATIVE SPLICING 27 4.36e-03 3.98e-02 0.36800 -0.053200 -0.364000 6.32e-01 1.05e-03
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES 30 4.41e-03 4.00e-02 0.32900 -0.027400 0.328000 7.95e-01 1.89e-03
REACTOME MRNA EDITING 10 4.49e-03 4.05e-02 0.67000 0.413000 0.527000 2.38e-02 3.87e-03
REACTOME SIGNALING BY NTRKS 132 4.55e-03 4.08e-02 0.18600 -0.126000 -0.136000 1.27e-02 6.82e-03
REACTOME RNA POLYMERASE III CHAIN ELONGATION 18 4.69e-03 4.17e-02 0.48100 -0.204000 -0.436000 1.34e-01 1.38e-03
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS 16 4.70e-03 4.17e-02 0.47700 0.076300 0.471000 5.97e-01 1.12e-03
REACTOME ADRENOCEPTORS 9 4.99e-03 4.40e-02 0.69800 -0.423000 -0.556000 2.81e-02 3.88e-03
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER 28 5.06e-03 4.44e-02 0.36200 -0.073900 -0.355000 4.99e-01 1.16e-03
REACTOME SYNTHESIS OF DNA 119 5.20e-03 4.50e-02 0.17400 -0.028800 -0.171000 5.87e-01 1.24e-03
REACTOME FOLDING OF ACTIN BY CCT TRIC 10 5.21e-03 4.50e-02 0.61000 -0.148000 -0.592000 4.17e-01 1.19e-03
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE 30 5.22e-03 4.50e-02 0.29500 -0.195000 0.222000 6.51e-02 3.55e-02
REACTOME COMPLEX I BIOGENESIS 49 5.24e-03 4.50e-02 0.25400 0.016500 -0.254000 8.41e-01 2.11e-03
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES 49 5.48e-03 4.67e-02 0.23900 0.078300 -0.226000 3.43e-01 6.19e-03
REACTOME METABOLISM OF NUCLEOTIDES 92 5.49e-03 4.67e-02 0.21200 -0.099500 -0.187000 9.90e-02 1.91e-03
REACTOME SUMOYLATION OF RNA BINDING PROTEINS 47 5.67e-03 4.80e-02 0.30200 -0.182000 -0.241000 3.07e-02 4.27e-03
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS 54 5.73e-03 4.80e-02 0.26600 -0.252000 -0.086100 1.37e-03 2.74e-01
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE 66 5.74e-03 4.80e-02 0.24800 -0.113000 -0.221000 1.13e-01 1.88e-03
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES 67 5.79e-03 4.80e-02 0.25200 -0.147000 -0.205000 3.79e-02 3.74e-03
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS 37 5.79e-03 4.80e-02 0.34100 -0.219000 -0.261000 2.13e-02 5.92e-03
REACTOME DRUG ADME 99 5.85e-03 4.82e-02 0.20900 0.150000 0.146000 1.01e-02 1.21e-02
REACTOME PRC2 METHYLATES HISTONES AND DNA 66 5.86e-03 4.82e-02 0.25400 -0.153000 -0.203000 3.22e-02 4.31e-03
REACTOME DISSOLUTION OF FIBRIN CLOT 13 6.17e-03 5.04e-02 0.57300 0.396000 0.414000 1.35e-02 9.73e-03
REACTOME TNF SIGNALING 54 6.24e-03 5.08e-02 0.26700 -0.248000 -0.101000 1.64e-03 2.00e-01
REACTOME DIGESTION AND ABSORPTION 24 6.46e-03 5.23e-02 0.41600 0.244000 0.337000 3.89e-02 4.22e-03
REACTOME MEIOTIC RECOMBINATION 81 6.67e-03 5.35e-02 0.21900 -0.091600 -0.199000 1.54e-01 1.95e-03
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM 9 6.68e-03 5.35e-02 0.54300 -0.203000 0.503000 2.93e-01 8.93e-03
REACTOME CILIUM ASSEMBLY 190 6.75e-03 5.38e-02 0.13700 -0.033700 -0.133000 4.23e-01 1.57e-03
REACTOME G1 S DNA DAMAGE CHECKPOINTS 67 6.82e-03 5.41e-02 0.22800 -0.048200 -0.223000 4.95e-01 1.60e-03
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION 23 6.93e-03 5.47e-02 0.41600 -0.208000 -0.361000 8.41e-02 2.76e-03
REACTOME ACTIVATION OF BH3 ONLY PROTEINS 30 7.18e-03 5.64e-02 0.35400 -0.327000 -0.135000 1.92e-03 2.01e-01
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE 91 7.24e-03 5.65e-02 0.19300 -0.036400 -0.190000 5.49e-01 1.74e-03
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 679 7.25e-03 5.65e-02 0.07930 -0.059000 -0.052900 8.86e-03 1.90e-02
REACTOME P75NTR SIGNALS VIA NF KB 15 7.41e-03 5.69e-02 0.46900 -0.464000 -0.067300 1.86e-03 6.52e-01
REACTOME BIOLOGICAL OXIDATIONS 207 7.41e-03 5.69e-02 0.12700 0.017800 0.125000 6.58e-01 1.87e-03
REACTOME SIGNALING BY PTK6 54 7.43e-03 5.69e-02 0.23300 -0.232000 0.021900 3.25e-03 7.80e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS 15 7.45e-03 5.69e-02 0.45100 0.001550 -0.451000 9.92e-01 2.51e-03
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2 77 7.53e-03 5.72e-02 0.20000 -0.001610 -0.200000 9.81e-01 2.46e-03
REACTOME PEPTIDE LIGAND BINDING RECEPTORS 187 7.80e-03 5.88e-02 0.14700 0.085500 0.119000 4.39e-02 4.89e-03
REACTOME MYD88 INDEPENDENT TLR4 CASCADE 103 7.84e-03 5.88e-02 0.19800 -0.159000 -0.118000 5.45e-03 3.84e-02
REACTOME RHO GTPASES ACTIVATE PKNS 87 7.85e-03 5.88e-02 0.21700 -0.152000 -0.154000 1.40e-02 1.32e-02
REACTOME FOXO MEDIATED TRANSCRIPTION 62 7.93e-03 5.91e-02 0.25000 -0.217000 -0.123000 3.07e-03 9.29e-02
REACTOME SIGNALING BY FGFR2 IIIA TM 19 7.96e-03 5.91e-02 0.37900 0.076700 -0.372000 5.63e-01 5.05e-03
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS 12 8.19e-03 6.04e-02 0.56900 0.484000 0.300000 3.71e-03 7.19e-02
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT 31 8.20e-03 6.04e-02 0.33600 -0.321000 -0.099200 1.97e-03 3.39e-01
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX 85 8.60e-03 6.30e-02 0.21100 -0.101000 -0.186000 1.09e-01 3.10e-03
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 99 8.68e-03 6.31e-02 0.20000 -0.129000 -0.154000 2.71e-02 8.23e-03
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS 46 8.70e-03 6.31e-02 0.29300 -0.183000 -0.229000 3.16e-02 7.27e-03
REACTOME PCP CE PATHWAY 91 8.72e-03 6.31e-02 0.18200 -0.003880 -0.182000 9.49e-01 2.77e-03
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY 72 8.82e-03 6.31e-02 0.20900 -0.024900 -0.208000 7.15e-01 2.32e-03
REACTOME LGI ADAM INTERACTIONS 14 8.83e-03 6.31e-02 0.43000 -0.413000 0.121000 7.48e-03 4.35e-01
REACTOME NEUTROPHIL DEGRANULATION 459 8.84e-03 6.31e-02 0.07620 -0.020500 0.073400 4.53e-01 7.15e-03
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION 89 8.98e-03 6.39e-02 0.21000 -0.133000 -0.163000 3.02e-02 7.86e-03
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 60 9.46e-03 6.66e-02 0.25100 -0.135000 -0.212000 7.00e-02 4.51e-03
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES 12 9.52e-03 6.66e-02 0.49600 -0.495000 -0.015700 2.96e-03 9.25e-01
REACTOME FATTY ACIDS 15 9.56e-03 6.66e-02 0.44000 0.002540 0.440000 9.86e-01 3.16e-03
REACTOME SUMOYLATION 179 9.59e-03 6.66e-02 0.14800 -0.105000 -0.105000 1.54e-02 1.59e-02
REACTOME MEIOSIS 111 9.60e-03 6.66e-02 0.17800 -0.063100 -0.166000 2.51e-01 2.49e-03
REACTOME SNRNP ASSEMBLY 52 9.65e-03 6.66e-02 0.27300 -0.175000 -0.210000 2.90e-02 8.96e-03
REACTOME DAP12 INTERACTIONS 38 9.65e-03 6.66e-02 0.30400 0.283000 0.110000 2.54e-03 2.41e-01
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME 59 9.78e-03 6.72e-02 0.22000 0.006200 -0.220000 9.34e-01 3.52e-03
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE 76 9.98e-03 6.83e-02 0.22300 -0.126000 -0.184000 5.67e-02 5.56e-03
REACTOME HEMOSTASIS 585 1.05e-02 7.16e-02 0.07650 0.022800 0.073000 3.48e-01 2.59e-03
REACTOME GLUCOCORTICOID BIOSYNTHESIS 10 1.06e-02 7.16e-02 0.56100 0.111000 0.550000 5.45e-01 2.60e-03
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE 63 1.06e-02 7.16e-02 0.23700 -0.098700 -0.215000 1.75e-01 3.16e-03
REACTOME SENSORY PERCEPTION OF TASTE 41 1.06e-02 7.16e-02 0.23700 -0.122000 0.204000 1.75e-01 2.42e-02
REACTOME INTEGRATION OF PROVIRUS 9 1.09e-02 7.30e-02 0.61700 -0.230000 -0.572000 2.32e-01 2.95e-03
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY 54 1.10e-02 7.37e-02 0.22700 0.003340 -0.227000 9.66e-01 3.85e-03
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1 9 1.11e-02 7.38e-02 0.49800 -0.338000 0.365000 7.88e-02 5.76e-02
REACTOME CD28 DEPENDENT VAV1 PATHWAY 11 1.11e-02 7.38e-02 0.55800 0.515000 0.215000 3.10e-03 2.16e-01
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING 32 1.12e-02 7.39e-02 0.27900 -0.270000 0.070900 8.30e-03 4.88e-01
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 54 1.13e-02 7.45e-02 0.23200 -0.015700 -0.231000 8.42e-01 3.31e-03
REACTOME DUAL INCISION IN TC NER 63 1.16e-02 7.57e-02 0.22200 -0.046400 -0.217000 5.24e-01 2.85e-03
REACTOME RNA POLYMERASE I TRANSCRIPTION 103 1.17e-02 7.59e-02 0.18900 -0.112000 -0.152000 4.86e-02 7.57e-03
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING 23 1.20e-02 7.78e-02 0.40100 -0.308000 -0.256000 1.05e-02 3.37e-02
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS 37 1.21e-02 7.79e-02 0.29600 -0.092100 -0.282000 3.32e-01 3.03e-03
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES 49 1.21e-02 7.79e-02 0.27500 -0.190000 -0.199000 2.17e-02 1.58e-02
REACTOME DNA DAMAGE RECOGNITION IN GG NER 36 1.23e-02 7.87e-02 0.29100 -0.285000 -0.057200 3.06e-03 5.52e-01
REACTOME ALPHA DEFENSINS 9 1.24e-02 7.92e-02 0.54100 -0.040100 0.540000 8.35e-01 5.06e-03
REACTOME PTEN REGULATION 135 1.29e-02 8.21e-02 0.15900 -0.066800 -0.144000 1.80e-01 3.93e-03
REACTOME CHOLESTEROL BIOSYNTHESIS 25 1.30e-02 8.21e-02 0.37200 -0.326000 -0.180000 4.80e-03 1.20e-01
REACTOME ORGANIC ANION TRANSPORT 5 1.30e-02 8.21e-02 0.65800 -0.403000 0.520000 1.18e-01 4.40e-02
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS 309 1.33e-02 8.35e-02 0.10800 0.058800 0.090100 7.56e-02 6.53e-03
REACTOME INTERLEUKIN 1 SIGNALING 110 1.34e-02 8.41e-02 0.16600 -0.034800 -0.162000 5.28e-01 3.35e-03
REACTOME MAPK6 MAPK4 SIGNALING 90 1.37e-02 8.57e-02 0.17400 -0.006980 -0.174000 9.09e-01 4.27e-03
REACTOME SIGNALING BY GPCR 658 1.43e-02 8.87e-02 0.06570 0.004640 0.065600 8.39e-01 4.20e-03
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA 54 1.44e-02 8.91e-02 0.22300 -0.005720 -0.223000 9.42e-01 4.61e-03
REACTOME BASE EXCISION REPAIR 87 1.52e-02 9.40e-02 0.19800 -0.106000 -0.167000 8.78e-02 7.03e-03
REACTOME GLYCOLYSIS 70 1.53e-02 9.43e-02 0.22400 -0.168000 -0.148000 1.51e-02 3.26e-02
REACTOME INTERFERON GAMMA SIGNALING 89 1.57e-02 9.62e-02 0.18500 0.177000 0.054400 4.01e-03 3.76e-01
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS 35 1.58e-02 9.62e-02 0.31300 -0.187000 -0.251000 5.61e-02 1.00e-02
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE 35 1.60e-02 9.72e-02 0.30600 -0.270000 -0.143000 5.64e-03 1.43e-01
REACTOME ACTIVATION OF C3 AND C5 5 1.61e-02 9.73e-02 0.69200 -0.102000 0.684000 6.92e-01 8.05e-03
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION 80 1.64e-02 9.91e-02 0.20300 -0.099700 -0.177000 1.23e-01 6.30e-03
REACTOME ENOS ACTIVATION 11 1.66e-02 1.00e-01 0.51100 -0.498000 -0.115000 4.22e-03 5.11e-01
REACTOME GLUCURONIDATION 19 1.71e-02 1.02e-01 0.41900 0.345000 0.238000 9.21e-03 7.25e-02
REACTOME RNA POLYMERASE III TRANSCRIPTION 41 1.74e-02 1.04e-01 0.27600 -0.113000 -0.252000 2.11e-01 5.24e-03
REACTOME CREATION OF C4 AND C2 ACTIVATORS 14 1.75e-02 1.04e-01 0.48300 0.253000 0.412000 1.01e-01 7.62e-03
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF 53 1.75e-02 1.04e-01 0.25200 -0.195000 -0.161000 1.42e-02 4.30e-02
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION 20 1.78e-02 1.05e-01 0.32900 0.107000 -0.312000 4.08e-01 1.59e-02
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND 21 1.80e-02 1.06e-01 0.39600 0.223000 0.327000 7.64e-02 9.52e-03
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION 15 1.80e-02 1.06e-01 0.41700 -0.416000 -0.033600 5.30e-03 8.22e-01
REACTOME NUCLEAR ENVELOPE BREAKDOWN 52 1.82e-02 1.06e-01 0.25400 -0.196000 -0.160000 1.43e-02 4.55e-02
REACTOME PROGRAMMED CELL DEATH 204 1.82e-02 1.06e-01 0.12500 -0.110000 -0.059600 6.61e-03 1.43e-01
REACTOME FORMATION OF APOPTOSOME 10 1.86e-02 1.08e-01 0.47900 -0.472000 0.078800 9.75e-03 6.66e-01
REACTOME HOMOLOGY DIRECTED REPAIR 134 1.87e-02 1.08e-01 0.15700 -0.090400 -0.128000 7.10e-02 1.05e-02
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER 28 1.87e-02 1.08e-01 0.34100 -0.187000 -0.284000 8.63e-02 9.17e-03
REACTOME BUDDING AND MATURATION OF HIV VIRION 28 1.88e-02 1.08e-01 0.31600 -0.308000 -0.070100 4.82e-03 5.21e-01
REACTOME DIGESTION 19 1.92e-02 1.09e-01 0.41300 0.235000 0.340000 7.65e-02 1.03e-02
REACTOME FCERI MEDIATED NF KB ACTIVATION 78 1.93e-02 1.09e-01 0.18000 -0.009750 -0.180000 8.82e-01 5.96e-03
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS 87 1.93e-02 1.09e-01 0.17100 -0.009460 -0.171000 8.79e-01 5.96e-03
REACTOME NERVOUS SYSTEM DEVELOPMENT 552 1.94e-02 1.09e-01 0.07470 -0.028300 -0.069200 2.56e-01 5.53e-03
REACTOME COBALAMIN CBL METABOLISM 7 1.95e-02 1.09e-01 0.60400 -0.047900 -0.602000 8.26e-01 5.77e-03
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY 36 1.95e-02 1.09e-01 0.30100 -0.185000 -0.238000 5.47e-02 1.35e-02
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING 145 1.95e-02 1.09e-01 0.13700 -0.024800 -0.135000 6.06e-01 5.14e-03
REACTOME HDACS DEACETYLATE HISTONES 87 1.96e-02 1.09e-01 0.19400 -0.120000 -0.153000 5.36e-02 1.38e-02
REACTOME ASSEMBLY OF THE HIV VIRION 16 1.97e-02 1.09e-01 0.40600 -0.402000 -0.055700 5.39e-03 6.99e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS 8 1.99e-02 1.10e-01 0.63300 -0.352000 -0.526000 8.48e-02 1.00e-02
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY 67 1.99e-02 1.10e-01 0.19400 -0.009480 -0.193000 8.93e-01 6.22e-03
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 41 2.01e-02 1.11e-01 0.23200 0.050000 -0.226000 5.80e-01 1.22e-02
REACTOME DNA DAMAGE BYPASS 47 2.02e-02 1.11e-01 0.26400 -0.190000 -0.183000 2.41e-02 2.98e-02
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION 18 2.03e-02 1.11e-01 0.41400 -0.365000 -0.196000 7.32e-03 1.51e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST 14 2.04e-02 1.11e-01 0.47600 -0.257000 -0.400000 9.53e-02 9.58e-03
REACTOME COLLAGEN DEGRADATION 59 2.05e-02 1.12e-01 0.18500 -0.081000 0.166000 2.82e-01 2.71e-02
REACTOME BASE EXCISION REPAIR AP SITE FORMATION 59 2.07e-02 1.12e-01 0.23300 -0.134000 -0.190000 7.40e-02 1.16e-02
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1 9 2.08e-02 1.12e-01 0.59200 -0.327000 -0.494000 8.92e-02 1.03e-02
REACTOME REGULATION OF TP53 ACTIVITY 156 2.09e-02 1.12e-01 0.14400 -0.114000 -0.088300 1.43e-02 5.72e-02
REACTOME DEGRADATION OF DVL 56 2.10e-02 1.12e-01 0.20300 0.018800 -0.202000 8.08e-01 8.95e-03
REACTOME UCH PROTEINASES 99 2.10e-02 1.12e-01 0.17000 -0.053100 -0.161000 3.61e-01 5.57e-03
REACTOME METABOLISM OF CARBOHYDRATES 273 2.12e-02 1.13e-01 0.10500 -0.096000 -0.042300 6.38e-03 2.29e-01
REACTOME IRAK1 RECRUITS IKK COMPLEX 12 2.13e-02 1.13e-01 0.49200 -0.458000 -0.178000 5.96e-03 2.86e-01
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER 76 2.16e-02 1.14e-01 0.19700 -0.078300 -0.181000 2.38e-01 6.43e-03
REACTOME COSTIMULATION BY THE CD28 FAMILY 64 2.16e-02 1.14e-01 0.21800 0.192000 0.103000 7.79e-03 1.54e-01
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS 40 2.18e-02 1.14e-01 0.28300 0.203000 0.197000 2.60e-02 3.08e-02
REACTOME TRANSPORT OF ORGANIC ANIONS 10 2.18e-02 1.14e-01 0.43700 -0.262000 0.350000 1.52e-01 5.52e-02
REACTOME 2 LTR CIRCLE FORMATION 7 2.19e-02 1.14e-01 0.61300 -0.115000 -0.602000 5.97e-01 5.80e-03
REACTOME PHASE II CONJUGATION OF COMPOUNDS 101 2.23e-02 1.16e-01 0.17600 0.144000 0.101000 1.22e-02 7.90e-02
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY 30 2.23e-02 1.16e-01 0.30400 -0.290000 -0.091100 5.91e-03 3.88e-01
REACTOME DNA METHYLATION 59 2.25e-02 1.16e-01 0.23000 -0.130000 -0.190000 8.47e-02 1.18e-02
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION 31 2.26e-02 1.16e-01 0.29900 -0.089400 -0.285000 3.89e-01 5.98e-03
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL 19 2.31e-02 1.19e-01 0.32300 -0.296000 0.128000 2.53e-02 3.35e-01
REACTOME UNFOLDED PROTEIN RESPONSE UPR 88 2.33e-02 1.19e-01 0.18700 -0.104000 -0.156000 9.29e-02 1.15e-02
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL 8 2.33e-02 1.19e-01 0.62600 -0.474000 -0.410000 2.02e-02 4.48e-02
REACTOME REGULATION OF RAS BY GAPS 67 2.41e-02 1.22e-01 0.18600 0.002770 -0.186000 9.69e-01 8.60e-03
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 7 2.42e-02 1.22e-01 0.54600 -0.120000 0.533000 5.82e-01 1.46e-02
REACTOME PREGNENOLONE BIOSYNTHESIS 12 2.42e-02 1.22e-01 0.40000 -0.357000 0.180000 3.21e-02 2.80e-01
REACTOME HCMV EARLY EVENTS 130 2.43e-02 1.22e-01 0.15400 -0.087400 -0.126000 8.55e-02 1.29e-02
REACTOME SYNTHESIS OF PE 13 2.43e-02 1.22e-01 0.44500 -0.436000 -0.087400 6.48e-03 5.85e-01
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES 254 2.45e-02 1.23e-01 0.08820 -0.034400 0.081200 3.45e-01 2.60e-02
REACTOME INTERLEUKIN 17 SIGNALING 66 2.46e-02 1.23e-01 0.20100 -0.194000 -0.054600 6.50e-03 4.44e-01
REACTOME EXTRACELLULAR MATRIX ORGANIZATION 289 2.46e-02 1.23e-01 0.09330 0.012700 0.092400 7.10e-01 6.90e-03
REACTOME CYTOPROTECTION BY HMOX1 59 2.46e-02 1.23e-01 0.22900 -0.146000 -0.176000 5.20e-02 1.93e-02
REACTOME PKMTS METHYLATE HISTONE LYSINES 63 2.47e-02 1.23e-01 0.18700 0.016700 -0.187000 8.19e-01 1.04e-02
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING 5 2.49e-02 1.23e-01 0.70000 -0.695000 -0.083700 7.11e-03 7.46e-01
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE 93 2.49e-02 1.23e-01 0.16800 -0.041800 -0.163000 4.86e-01 6.58e-03
REACTOME SIGNALING BY FGFR2 IN DISEASE 41 2.50e-02 1.23e-01 0.26000 -0.090200 -0.244000 3.18e-01 6.98e-03
REACTOME DARPP 32 EVENTS 24 2.51e-02 1.23e-01 0.35800 -0.270000 -0.236000 2.20e-02 4.57e-02
REACTOME TRANSPORT OF SMALL MOLECULES 691 2.52e-02 1.23e-01 0.05350 -0.047900 0.023700 3.21e-02 2.90e-01
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE 39 2.52e-02 1.23e-01 0.27800 -0.231000 -0.155000 1.27e-02 9.36e-02
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION 13 2.56e-02 1.24e-01 0.48600 -0.341000 -0.346000 3.30e-02 3.08e-02
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS 92 2.57e-02 1.24e-01 0.17400 -0.162000 -0.064000 7.40e-03 2.88e-01
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES 505 2.57e-02 1.24e-01 0.07230 -0.070400 -0.016200 6.84e-03 5.33e-01
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS 74 2.58e-02 1.24e-01 0.20400 -0.135000 -0.153000 4.50e-02 2.33e-02
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION 69 2.61e-02 1.25e-01 0.21100 -0.143000 -0.155000 4.06e-02 2.60e-02
REACTOME LEISHMANIA INFECTION 156 2.61e-02 1.25e-01 0.10900 -0.091800 0.058800 4.78e-02 2.05e-01
REACTOME NUCLEAR IMPORT OF REV PROTEIN 34 2.62e-02 1.25e-01 0.29900 -0.195000 -0.227000 4.86e-02 2.22e-02
REACTOME INTERLEUKIN 36 PATHWAY 7 2.63e-02 1.25e-01 0.53900 0.524000 -0.125000 1.64e-02 5.66e-01
REACTOME G2 M DNA DAMAGE CHECKPOINT 90 2.64e-02 1.25e-01 0.18300 -0.108000 -0.147000 7.53e-02 1.57e-02
REACTOME REGULATION OF PTEN LOCALIZATION 8 2.66e-02 1.26e-01 0.47700 -0.273000 0.391000 1.82e-01 5.52e-02
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX 51 2.73e-02 1.29e-01 0.22700 -0.066400 -0.217000 4.12e-01 7.36e-03
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES 112 2.75e-02 1.29e-01 0.16000 -0.076400 -0.141000 1.62e-01 1.02e-02
REACTOME DEFECTIVE GALNT3 CAUSES HFTC 14 2.77e-02 1.30e-01 0.39800 -0.005490 0.398000 9.72e-01 9.90e-03
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE 100 2.79e-02 1.30e-01 0.17000 -0.147000 -0.085800 1.13e-02 1.38e-01
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1 46 2.81e-02 1.31e-01 0.24300 -0.225000 -0.090700 8.21e-03 2.87e-01
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR 79 2.81e-02 1.31e-01 0.17900 -0.041700 -0.174000 5.22e-01 7.53e-03
REACTOME DIGESTION OF DIETARY CARBOHYDRATE 9 2.83e-02 1.31e-01 0.57500 0.376000 0.435000 5.09e-02 2.37e-02
REACTOME SPRY REGULATION OF FGF SIGNALING 16 2.84e-02 1.31e-01 0.33500 -0.280000 0.184000 5.26e-02 2.02e-01
REACTOME RECYCLING OF BILE ACIDS AND SALTS 18 2.84e-02 1.31e-01 0.34300 -0.031400 0.342000 8.18e-01 1.21e-02
REACTOME LINOLEIC ACID LA METABOLISM 7 2.93e-02 1.35e-01 0.64000 -0.540000 -0.344000 1.34e-02 1.15e-01
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN 32 2.94e-02 1.35e-01 0.30300 -0.189000 -0.237000 6.44e-02 2.05e-02
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING 34 2.96e-02 1.35e-01 0.28400 -0.256000 -0.123000 9.74e-03 2.14e-01
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS 18 2.97e-02 1.35e-01 0.32800 -0.086000 0.317000 5.28e-01 1.99e-02
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS 137 3.01e-02 1.37e-01 0.14100 -0.128000 -0.058500 9.52e-03 2.37e-01
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION 22 3.03e-02 1.37e-01 0.36500 -0.272000 -0.243000 2.74e-02 4.81e-02
REACTOME CYTOSOLIC TRNA AMINOACYLATION 22 3.03e-02 1.37e-01 0.33600 -0.081500 -0.326000 5.08e-01 8.20e-03
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE 16 3.05e-02 1.37e-01 0.42700 -0.280000 -0.322000 5.24e-02 2.57e-02
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION 12 3.05e-02 1.37e-01 0.49200 -0.377000 -0.317000 2.38e-02 5.73e-02
REACTOME KEAP1 NFE2L2 PATHWAY 104 3.09e-02 1.39e-01 0.15900 -0.058500 -0.148000 3.03e-01 9.05e-03
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK 28 3.17e-02 1.42e-01 0.30500 -0.108000 -0.285000 3.21e-01 9.15e-03
REACTOME G1 S SPECIFIC TRANSCRIPTION 28 3.17e-02 1.42e-01 0.32100 -0.238000 -0.216000 2.93e-02 4.80e-02
REACTOME DEATH RECEPTOR SIGNALING 142 3.19e-02 1.42e-01 0.14100 -0.119000 -0.074300 1.41e-02 1.27e-01
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR 68 3.22e-02 1.42e-01 0.20500 -0.129000 -0.160000 6.57e-02 2.28e-02
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE 63 3.23e-02 1.42e-01 0.16600 -0.092000 0.138000 2.07e-01 5.81e-02
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS 23 3.23e-02 1.42e-01 0.30300 -0.303000 0.007030 1.18e-02 9.53e-01
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION 192 3.24e-02 1.42e-01 0.10200 -0.014200 0.101000 7.34e-01 1.54e-02
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING 61 3.28e-02 1.44e-01 0.19400 -0.027500 -0.192000 7.11e-01 9.43e-03
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION 59 3.31e-02 1.45e-01 0.21800 -0.177000 -0.128000 1.85e-02 9.02e-02
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX 132 3.31e-02 1.45e-01 0.13300 0.022300 0.131000 6.58e-01 9.31e-03
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS 14 3.39e-02 1.48e-01 0.38800 -0.000491 0.388000 9.97e-01 1.19e-02
REACTOME SENSORY PERCEPTION OF SALTY TASTE 6 3.42e-02 1.48e-01 0.55300 -0.163000 0.529000 4.89e-01 2.49e-02
REACTOME G ALPHA I SIGNALLING EVENTS 293 3.46e-02 1.50e-01 0.09480 0.038700 0.086500 2.54e-01 1.09e-02
REACTOME ATORVASTATIN ADME 9 3.48e-02 1.50e-01 0.54200 0.248000 0.482000 1.98e-01 1.23e-02
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA 37 3.52e-02 1.52e-01 0.26100 -0.094700 -0.243000 3.19e-01 1.04e-02
REACTOME CELL CELL COMMUNICATION 126 3.55e-02 1.52e-01 0.12000 -0.039400 0.113000 4.46e-01 2.85e-02
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE 12 3.56e-02 1.52e-01 0.41400 -0.414000 0.009130 1.31e-02 9.56e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS 16 3.56e-02 1.52e-01 0.40800 0.200000 0.355000 1.66e-01 1.38e-02
REACTOME IRE1ALPHA ACTIVATES CHAPERONES 49 3.57e-02 1.52e-01 0.23700 -0.142000 -0.190000 8.58e-02 2.13e-02
REACTOME DOWNREGULATION OF ERBB2 SIGNALING 29 3.59e-02 1.52e-01 0.23900 -0.178000 0.160000 9.80e-02 1.37e-01
REACTOME GERM LAYER FORMATION AT GASTRULATION 17 3.59e-02 1.52e-01 0.36200 -0.049400 -0.359000 7.25e-01 1.05e-02
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS 7 3.60e-02 1.52e-01 0.49500 -0.440000 0.226000 4.39e-02 2.99e-01
REACTOME ONCOGENE INDUCED SENESCENCE 35 3.65e-02 1.54e-01 0.24200 -0.242000 0.003640 1.33e-02 9.70e-01
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS 93 3.68e-02 1.55e-01 0.17200 -0.111000 -0.132000 6.47e-02 2.77e-02
REACTOME PROTEIN UBIQUITINATION 76 3.71e-02 1.56e-01 0.18700 -0.161000 -0.094400 1.51e-02 1.55e-01
REACTOME FORMATION OF INCISION COMPLEX IN GG NER 40 3.72e-02 1.56e-01 0.26100 -0.211000 -0.154000 2.12e-02 9.28e-02
REACTOME SIGNALING BY ERBB2 50 3.75e-02 1.57e-01 0.18300 -0.159000 0.090800 5.16e-02 2.67e-01
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING 12 3.79e-02 1.58e-01 0.46400 -0.412000 -0.213000 1.35e-02 2.02e-01
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX 9 3.82e-02 1.59e-01 0.43100 -0.376000 0.211000 5.10e-02 2.74e-01
REACTOME DOWNREGULATION OF ERBB4 SIGNALING 9 3.86e-02 1.60e-01 0.42400 -0.324000 0.274000 9.28e-02 1.54e-01
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION 89 3.87e-02 1.60e-01 0.17300 -0.098100 -0.143000 1.10e-01 1.97e-02
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS 50 3.89e-02 1.60e-01 0.23200 -0.186000 -0.138000 2.29e-02 9.05e-02
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY 33 3.89e-02 1.60e-01 0.22400 -0.193000 0.114000 5.56e-02 2.57e-01
REACTOME EICOSANOIDS 12 3.90e-02 1.60e-01 0.41500 0.019000 0.415000 9.09e-01 1.28e-02
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION 8 3.91e-02 1.60e-01 0.57900 0.350000 0.461000 8.61e-02 2.40e-02
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS 15 3.92e-02 1.60e-01 0.33300 -0.293000 0.157000 4.91e-02 2.91e-01
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS 86 4.04e-02 1.64e-01 0.16800 -0.061700 -0.156000 3.23e-01 1.22e-02
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL 12 4.05e-02 1.64e-01 0.40900 -0.409000 -0.002300 1.42e-02 9.89e-01
REACTOME ION CHANNEL TRANSPORT 171 4.06e-02 1.64e-01 0.10000 -0.035400 0.093900 4.25e-01 3.43e-02
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC 28 4.11e-02 1.66e-01 0.26200 0.017100 -0.262000 8.76e-01 1.65e-02
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS 17 4.12e-02 1.66e-01 0.39500 -0.312000 -0.242000 2.60e-02 8.44e-02
REACTOME STABILIZATION OF P53 56 4.14e-02 1.66e-01 0.18900 -0.000659 -0.189000 9.93e-01 1.46e-02
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION 10 4.14e-02 1.66e-01 0.49100 0.181000 0.456000 3.21e-01 1.25e-02
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE 109 4.24e-02 1.70e-01 0.14300 -0.139000 -0.030500 1.20e-02 5.83e-01
REACTOME THE PHOTOTRANSDUCTION CASCADE 32 4.35e-02 1.74e-01 0.27400 0.106000 0.252000 3.00e-01 1.35e-02
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE 81 4.38e-02 1.74e-01 0.17800 -0.147000 -0.100000 2.20e-02 1.19e-01
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS 11 4.38e-02 1.74e-01 0.46100 0.158000 0.433000 3.64e-01 1.29e-02
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS 296 4.39e-02 1.74e-01 0.09440 -0.073400 -0.059400 3.00e-02 7.89e-02
REACTOME ERKS ARE INACTIVATED 13 4.40e-02 1.74e-01 0.44900 -0.318000 -0.317000 4.73e-02 4.79e-02
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG 5 4.45e-02 1.74e-01 0.58100 -0.553000 0.178000 3.23e-02 4.90e-01
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS 11 4.45e-02 1.74e-01 0.43100 -0.042800 -0.429000 8.06e-01 1.38e-02
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING 26 4.46e-02 1.74e-01 0.28200 -0.280000 -0.035800 1.34e-02 7.52e-01
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES 29 4.46e-02 1.74e-01 0.29300 -0.254000 -0.147000 1.80e-02 1.69e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING 28 4.46e-02 1.74e-01 0.24400 -0.230000 0.081000 3.48e-02 4.58e-01
REACTOME RRNA PROCESSING IN THE MITOCHONDRION 9 4.52e-02 1.76e-01 0.43600 0.114000 -0.420000 5.53e-01 2.90e-02
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH 61 4.55e-02 1.77e-01 0.16000 -0.086000 0.135000 2.45e-01 6.78e-02
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS 9 4.57e-02 1.77e-01 0.50100 0.152000 0.477000 4.31e-01 1.32e-02
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE 17 4.58e-02 1.77e-01 0.33900 -0.339000 -0.011900 1.55e-02 9.32e-01
REACTOME RAC3 GTPASE CYCLE 86 4.61e-02 1.78e-01 0.14000 -0.039800 0.134000 5.23e-01 3.13e-02
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3 94 4.64e-02 1.79e-01 0.13700 0.022400 -0.136000 7.08e-01 2.31e-02
REACTOME SIGNALING BY FGFR2 71 4.68e-02 1.80e-01 0.19000 -0.141000 -0.128000 4.01e-02 6.24e-02
REACTOME ETHANOL OXIDATION 11 4.71e-02 1.81e-01 0.42500 0.033900 0.423000 8.46e-01 1.50e-02
REACTOME MTOR SIGNALLING 40 4.73e-02 1.81e-01 0.25000 -0.138000 -0.208000 1.31e-01 2.28e-02
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE 25 4.75e-02 1.81e-01 0.29900 -0.092000 -0.285000 4.26e-01 1.38e-02
REACTOME SIGNALING BY FGFR3 39 4.75e-02 1.81e-01 0.21500 -0.214000 0.021500 2.06e-02 8.16e-01
REACTOME CELLULAR RESPONSE TO HEAT STRESS 99 4.77e-02 1.81e-01 0.15900 -0.133000 -0.086700 2.25e-02 1.36e-01
REACTOME HEME BIOSYNTHESIS 13 4.80e-02 1.82e-01 0.44200 -0.337000 -0.286000 3.55e-02 7.46e-02
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING 32 5.02e-02 1.90e-01 0.22600 -0.217000 0.063700 3.35e-02 5.33e-01
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9 7 5.05e-02 1.90e-01 0.53200 -0.528000 -0.064400 1.55e-02 7.68e-01
REACTOME RUNX2 REGULATES BONE DEVELOPMENT 29 5.13e-02 1.93e-01 0.29300 -0.203000 -0.212000 5.91e-02 4.83e-02
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE 5 5.20e-02 1.95e-01 0.66900 0.621000 0.250000 1.62e-02 3.33e-01
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER 49 5.25e-02 1.97e-01 0.22400 -0.147000 -0.169000 7.42e-02 4.06e-02
REACTOME SCAVENGING BY CLASS A RECEPTORS 18 5.30e-02 1.98e-01 0.35700 0.321000 0.156000 1.83e-02 2.52e-01
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 11 5.33e-02 1.99e-01 0.40000 0.027800 -0.400000 8.73e-01 2.18e-02
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY 34 5.40e-02 2.01e-01 0.24500 -0.053100 -0.239000 5.92e-01 1.58e-02
REACTOME SARS COV 1 HOST INTERACTIONS 94 5.41e-02 2.01e-01 0.16100 -0.122000 -0.105000 4.09e-02 7.72e-02
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS 21 5.44e-02 2.02e-01 0.33800 0.197000 0.275000 1.18e-01 2.94e-02
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND 9 5.46e-02 2.02e-01 0.40600 -0.354000 0.200000 6.62e-02 2.99e-01
REACTOME JOSEPHIN DOMAIN DUBS 11 5.47e-02 2.02e-01 0.42900 -0.419000 -0.088700 1.60e-02 6.10e-01
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES 33 5.49e-02 2.02e-01 0.21300 -0.190000 0.097200 5.94e-02 3.34e-01
REACTOME N GLYCAN ANTENNAE ELONGATION 15 5.49e-02 2.02e-01 0.31000 -0.242000 0.195000 1.05e-01 1.92e-01
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING 13 5.52e-02 2.02e-01 0.33600 -0.284000 0.179000 7.62e-02 2.64e-01
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS 58 5.54e-02 2.03e-01 0.19200 -0.182000 -0.059400 1.64e-02 4.34e-01
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS 63 5.66e-02 2.06e-01 0.17600 0.026900 0.174000 7.12e-01 1.71e-02
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING 66 5.68e-02 2.07e-01 0.19100 -0.137000 -0.133000 5.46e-02 6.09e-02
REACTOME FERTILIZATION 25 5.71e-02 2.07e-01 0.30700 0.174000 0.252000 1.32e-01 2.91e-02
REACTOME RAB GERANYLGERANYLATION 55 5.80e-02 2.09e-01 0.17700 -0.176000 0.012700 2.39e-02 8.71e-01
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN 37 5.80e-02 2.09e-01 0.25200 -0.203000 -0.150000 3.28e-02 1.14e-01
REACTOME INTERLEUKIN 18 SIGNALING 8 5.80e-02 2.09e-01 0.54600 0.387000 0.386000 5.81e-02 5.90e-02
REACTOME RHOBTB3 ATPASE CYCLE 8 5.82e-02 2.10e-01 0.45100 -0.443000 0.080400 2.98e-02 6.94e-01
REACTOME COLLAGEN CHAIN TRIMERIZATION 41 5.85e-02 2.10e-01 0.19400 -0.057400 0.186000 5.25e-01 3.98e-02
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB 5 5.87e-02 2.10e-01 0.53000 -0.374000 0.375000 1.47e-01 1.46e-01
REACTOME REGULATION OF INSULIN SECRETION 76 5.88e-02 2.10e-01 0.13700 -0.115000 0.074800 8.23e-02 2.60e-01
REACTOME GASTRULATION 49 5.97e-02 2.13e-01 0.19100 -0.007200 -0.191000 9.31e-01 2.06e-02
REACTOME DISEASES OF METABOLISM 231 6.01e-02 2.14e-01 0.07950 -0.070000 0.037700 6.71e-02 3.24e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS 9 6.03e-02 2.14e-01 0.50400 0.272000 0.424000 1.58e-01 2.77e-02
REACTOME CD22 MEDIATED BCR REGULATION 5 6.20e-02 2.19e-01 0.55300 -0.150000 0.532000 5.61e-01 3.94e-02
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION 8 6.20e-02 2.19e-01 0.47000 -0.019600 -0.470000 9.24e-01 2.13e-02
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION 26 6.21e-02 2.19e-01 0.24000 0.078800 -0.226000 4.87e-01 4.56e-02
REACTOME G ALPHA Q SIGNALLING EVENTS 199 6.25e-02 2.20e-01 0.09340 -0.000901 0.093400 9.83e-01 2.32e-02
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA 71 6.40e-02 2.25e-01 0.17700 -0.151000 -0.093500 2.82e-02 1.73e-01
REACTOME SIGNALING BY TGFB FAMILY MEMBERS 119 6.44e-02 2.25e-01 0.13900 -0.103000 -0.094100 5.30e-02 7.65e-02
REACTOME ABC TRANSPORTER DISORDERS 76 6.44e-02 2.25e-01 0.14700 0.010800 -0.147000 8.71e-01 2.67e-02
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES 22 6.45e-02 2.25e-01 0.30100 0.089200 0.288000 4.69e-01 1.94e-02
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A 5 6.46e-02 2.25e-01 0.66900 0.376000 0.554000 1.45e-01 3.20e-02
REACTOME CALNEXIN CALRETICULIN CYCLE 26 6.47e-02 2.25e-01 0.27100 -0.265000 -0.058300 1.94e-02 6.07e-01
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY 41 6.49e-02 2.25e-01 0.22400 -0.210000 -0.078600 2.03e-02 3.84e-01
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA 63 6.57e-02 2.28e-01 0.18800 -0.104000 -0.157000 1.53e-01 3.16e-02
REACTOME SARS COV 1 INFECTION 138 6.60e-02 2.28e-01 0.12700 -0.107000 -0.068600 3.03e-02 1.64e-01
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA 5 6.62e-02 2.28e-01 0.64300 -0.594000 -0.244000 2.14e-02 3.44e-01
REACTOME G ALPHA S SIGNALLING EVENTS 153 6.73e-02 2.32e-01 0.09450 -0.078200 0.053100 9.51e-02 2.57e-01
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS 28 6.75e-02 2.32e-01 0.26700 0.087700 0.252000 4.22e-01 2.08e-02
REACTOME GLUCOSE METABOLISM 90 6.86e-02 2.34e-01 0.15800 -0.099700 -0.122000 1.02e-01 4.51e-02
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS 22 6.87e-02 2.34e-01 0.26500 -0.261000 0.043100 3.39e-02 7.26e-01
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION 10 6.88e-02 2.34e-01 0.45300 -0.416000 -0.179000 2.28e-02 3.26e-01
REACTOME ERBB2 REGULATES CELL MOTILITY 15 6.88e-02 2.34e-01 0.29800 -0.234000 0.185000 1.16e-01 2.15e-01
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS 6 6.92e-02 2.35e-01 0.52800 0.004720 0.528000 9.84e-01 2.52e-02
REACTOME PEROXISOMAL PROTEIN IMPORT 62 6.99e-02 2.37e-01 0.17200 -0.169000 -0.032700 2.13e-02 6.56e-01
REACTOME EARLY PHASE OF HIV LIFE CYCLE 14 6.99e-02 2.37e-01 0.37600 -0.126000 -0.354000 4.15e-01 2.18e-02
REACTOME SIGNALING BY FGFR 84 7.05e-02 2.38e-01 0.16200 -0.129000 -0.097600 4.06e-02 1.22e-01
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE 43 7.06e-02 2.38e-01 0.21800 -0.089500 -0.199000 3.10e-01 2.40e-02
REACTOME ERK MAPK TARGETS 20 7.20e-02 2.42e-01 0.32800 -0.272000 -0.183000 3.51e-02 1.56e-01
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS 10 7.22e-02 2.42e-01 0.36100 -0.270000 0.240000 1.39e-01 1.89e-01
REACTOME ACYL CHAIN REMODELLING OF PC 27 7.24e-02 2.42e-01 0.22300 -0.196000 0.107000 7.84e-02 3.34e-01
REACTOME RESPONSE TO METAL IONS 14 7.25e-02 2.42e-01 0.35500 -0.351000 -0.049600 2.29e-02 7.48e-01
REACTOME TRANSPORT OF FATTY ACIDS 8 7.27e-02 2.43e-01 0.40500 -0.236000 0.330000 2.48e-01 1.06e-01
REACTOME PROCESSING AND ACTIVATION OF SUMO 10 7.29e-02 2.43e-01 0.42000 -0.415000 -0.062600 2.29e-02 7.32e-01
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE 49 7.30e-02 2.43e-01 0.20100 -0.075200 -0.187000 3.62e-01 2.37e-02
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB 19 7.32e-02 2.43e-01 0.27600 -0.266000 0.072000 4.47e-02 5.87e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS 11 7.36e-02 2.43e-01 0.43500 -0.215000 -0.379000 2.16e-01 2.97e-02
REACTOME METABOLISM OF STEROIDS 150 7.38e-02 2.43e-01 0.10200 -0.102000 0.008240 3.11e-02 8.62e-01
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS 32 7.38e-02 2.43e-01 0.25300 -0.225000 -0.116000 2.75e-02 2.55e-01
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE 52 7.43e-02 2.44e-01 0.20100 -0.104000 -0.172000 1.93e-01 3.20e-02
REACTOME LDL REMODELING 6 7.45e-02 2.45e-01 0.58700 0.514000 0.282000 2.91e-02 2.32e-01
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS 53 7.54e-02 2.47e-01 0.16000 -0.145000 0.067500 6.87e-02 3.96e-01
REACTOME HORMONE LIGAND BINDING RECEPTORS 11 7.58e-02 2.48e-01 0.34300 0.275000 -0.204000 1.14e-01 2.42e-01
REACTOME IRON UPTAKE AND TRANSPORT 55 7.69e-02 2.51e-01 0.19700 -0.155000 -0.121000 4.66e-02 1.20e-01
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES 78 7.70e-02 2.51e-01 0.15400 -0.041200 -0.148000 5.29e-01 2.36e-02
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC 196 7.71e-02 2.51e-01 0.10100 -0.044000 -0.091400 2.88e-01 2.74e-02
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX 14 7.73e-02 2.51e-01 0.38100 -0.335000 -0.181000 2.99e-02 2.41e-01
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS 20 7.85e-02 2.54e-01 0.32400 -0.261000 -0.192000 4.32e-02 1.37e-01
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE 17 7.89e-02 2.55e-01 0.32900 -0.315000 -0.092300 2.43e-02 5.10e-01
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION 27 7.95e-02 2.56e-01 0.26900 -0.109000 -0.246000 3.29e-01 2.71e-02
REACTOME TCR SIGNALING 113 7.98e-02 2.57e-01 0.11100 0.106000 -0.031400 5.09e-02 5.64e-01
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS 39 7.99e-02 2.57e-01 0.23300 -0.163000 -0.166000 7.74e-02 7.21e-02
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS 5 8.01e-02 2.57e-01 0.51800 -0.484000 0.185000 6.08e-02 4.74e-01
REACTOME GPCR LIGAND BINDING 432 8.03e-02 2.57e-01 0.06390 0.011300 0.062900 6.88e-01 2.52e-02
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX 21 8.17e-02 2.61e-01 0.27000 -0.011100 0.270000 9.30e-01 3.24e-02
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B 24 8.18e-02 2.61e-01 0.23200 -0.207000 0.105000 7.95e-02 3.71e-01
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT 7 8.25e-02 2.62e-01 0.45300 0.074500 -0.447000 7.33e-01 4.07e-02
REACTOME RHOBTB1 GTPASE CYCLE 22 8.31e-02 2.64e-01 0.29400 -0.271000 -0.115000 2.80e-02 3.49e-01
REACTOME CARDIAC CONDUCTION 125 8.32e-02 2.64e-01 0.10100 -0.088000 0.049700 8.93e-02 3.37e-01
REACTOME P75NTR REGULATES AXONOGENESIS 8 8.36e-02 2.64e-01 0.41900 -0.411000 0.082600 4.41e-02 6.86e-01
REACTOME SLC TRANSPORTER DISORDERS 94 8.36e-02 2.64e-01 0.13200 -0.131000 -0.013000 2.79e-02 8.28e-01
REACTOME NUCLEOTIDE CATABOLISM 35 8.36e-02 2.64e-01 0.22800 -0.071600 -0.217000 4.64e-01 2.63e-02
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING 13 8.43e-02 2.65e-01 0.31600 -0.127000 0.289000 4.28e-01 7.10e-02
REACTOME RHOBTB GTPASE CYCLE 33 8.46e-02 2.65e-01 0.24600 -0.209000 -0.131000 3.79e-02 1.94e-01
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION 24 8.47e-02 2.65e-01 0.26800 -0.058500 -0.262000 6.20e-01 2.64e-02
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS 8 8.50e-02 2.66e-01 0.48800 -0.444000 -0.204000 2.98e-02 3.18e-01
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY 14 8.51e-02 2.66e-01 0.33000 0.006010 -0.330000 9.69e-01 3.28e-02
REACTOME G0 AND EARLY G1 27 8.56e-02 2.66e-01 0.27400 -0.162000 -0.221000 1.45e-01 4.67e-02
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 19 8.57e-02 2.66e-01 0.27900 -0.278000 0.021400 3.61e-02 8.72e-01
REACTOME DEADENYLATION DEPENDENT MRNA DECAY 56 8.63e-02 2.68e-01 0.19200 -0.130000 -0.141000 9.20e-02 6.88e-02
REACTOME INTEGRATION OF ENERGY METABOLISM 104 8.67e-02 2.69e-01 0.10900 -0.089100 0.062600 1.17e-01 2.70e-01
REACTOME PARACETAMOL ADME 28 8.79e-02 2.71e-01 0.27000 0.182000 0.199000 9.57e-02 6.82e-02
REACTOME MAPK FAMILY SIGNALING CASCADES 312 8.79e-02 2.71e-01 0.07890 -0.035700 -0.070300 2.79e-01 3.28e-02
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS 26 8.91e-02 2.74e-01 0.24000 -0.240000 0.004430 3.44e-02 9.69e-01
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION 84 9.04e-02 2.77e-01 0.15100 -0.074600 -0.132000 2.37e-01 3.67e-02
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM 45 9.04e-02 2.77e-01 0.18500 -0.185000 -0.009610 3.20e-02 9.11e-01
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE 6 9.05e-02 2.77e-01 0.45700 0.192000 -0.415000 4.16e-01 7.86e-02
REACTOME REGULATED PROTEOLYSIS OF P75NTR 11 9.08e-02 2.78e-01 0.41900 -0.212000 -0.361000 2.23e-01 3.82e-02
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES 64 9.13e-02 2.79e-01 0.13800 -0.120000 0.069100 9.76e-02 3.39e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS 7 9.18e-02 2.80e-01 0.48500 -0.093100 -0.476000 6.70e-01 2.92e-02
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK 46 9.25e-02 2.81e-01 0.20500 -0.108000 -0.174000 2.07e-01 4.10e-02
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA 11 9.26e-02 2.81e-01 0.42400 0.261000 0.334000 1.33e-01 5.54e-02
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE 11 9.33e-02 2.83e-01 0.39400 -0.379000 -0.109000 2.95e-02 5.31e-01
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC 21 9.37e-02 2.83e-01 0.28600 -0.274000 -0.083300 2.97e-02 5.09e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS 6 9.38e-02 2.83e-01 0.48900 -0.488000 0.026500 3.83e-02 9.11e-01
REACTOME PEXOPHAGY 11 9.38e-02 2.83e-01 0.35700 -0.355000 0.037900 4.17e-02 8.28e-01
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT 152 9.45e-02 2.84e-01 0.11200 -0.057500 -0.096400 2.22e-01 4.04e-02
REACTOME DEFECTIVE F9 ACTIVATION 5 9.46e-02 2.84e-01 0.48500 -0.292000 0.388000 2.58e-01 1.33e-01
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE 24 9.58e-02 2.87e-01 0.23500 -0.230000 0.049300 5.16e-02 6.76e-01
REACTOME EXTENSION OF TELOMERES 49 9.61e-02 2.87e-01 0.18100 -0.031000 -0.178000 7.08e-01 3.10e-02
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS 8 9.61e-02 2.87e-01 0.49500 0.324000 0.373000 1.12e-01 6.75e-02
REACTOME AMINO ACIDS REGULATE MTORC1 53 9.66e-02 2.88e-01 0.18900 -0.096100 -0.162000 2.26e-01 4.11e-02
REACTOME SULFUR AMINO ACID METABOLISM 28 9.70e-02 2.88e-01 0.26300 -0.160000 -0.209000 1.44e-01 5.58e-02
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION 21 9.70e-02 2.88e-01 0.28100 0.067600 0.272000 5.92e-01 3.08e-02
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS 33 9.71e-02 2.88e-01 0.23100 -0.083300 -0.215000 4.08e-01 3.23e-02
REACTOME FREE FATTY ACID RECEPTORS 5 9.75e-02 2.88e-01 0.48100 -0.319000 0.359000 2.16e-01 1.64e-01
REACTOME RELAXIN RECEPTORS 8 9.76e-02 2.88e-01 0.45900 0.440000 0.131000 3.11e-02 5.21e-01
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS 9 9.82e-02 2.89e-01 0.43400 -0.414000 -0.129000 3.15e-02 5.01e-01
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE 19 9.92e-02 2.91e-01 0.29900 -0.284000 -0.095100 3.22e-02 4.73e-01
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION 41 9.93e-02 2.91e-01 0.17800 -0.174000 0.037800 5.36e-02 6.75e-01
REACTOME STIMULI SENSING CHANNELS 100 9.93e-02 2.91e-01 0.10800 -0.066200 0.084800 2.53e-01 1.43e-01
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES 76 9.95e-02 2.91e-01 0.12300 -0.088100 0.085700 1.84e-01 1.96e-01
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX 10 9.98e-02 2.91e-01 0.34800 -0.320000 0.137000 7.96e-02 4.54e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION 36 9.98e-02 2.91e-01 0.23100 -0.144000 -0.180000 1.34e-01 6.15e-02
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 22 1.00e-01 2.93e-01 0.29600 -0.198000 -0.220000 1.08e-01 7.45e-02
REACTOME SIGNALING BY FGFR IN DISEASE 61 1.01e-01 2.93e-01 0.17800 -0.129000 -0.123000 8.22e-02 9.77e-02
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY 74 1.01e-01 2.94e-01 0.16000 -0.127000 -0.097900 5.88e-02 1.45e-01
REACTOME CS DS DEGRADATION 12 1.02e-01 2.95e-01 0.33300 -0.330000 0.046200 4.81e-02 7.81e-01
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION 74 1.03e-01 2.96e-01 0.12400 -0.093000 0.081800 1.67e-01 2.24e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX 91 1.03e-01 2.96e-01 0.14500 -0.105000 -0.100000 8.33e-02 9.92e-02
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE 15 1.04e-01 2.98e-01 0.34500 -0.157000 -0.307000 2.93e-01 3.94e-02
REACTOME TRAF6 MEDIATED NF KB ACTIVATION 24 1.04e-01 2.99e-01 0.26200 -0.076000 -0.251000 5.19e-01 3.35e-02
REACTOME METABOLISM OF COFACTORS 19 1.04e-01 2.99e-01 0.31500 -0.238000 -0.207000 7.24e-02 1.18e-01
REACTOME AMYLOID FIBER FORMATION 103 1.04e-01 2.99e-01 0.13300 -0.114000 -0.069700 4.59e-02 2.22e-01
REACTOME COPII MEDIATED VESICLE TRANSPORT 66 1.05e-01 3.00e-01 0.16500 -0.144000 -0.081000 4.28e-02 2.55e-01
REACTOME NOD1 2 SIGNALING PATHWAY 33 1.05e-01 3.00e-01 0.18800 -0.167000 0.086200 9.75e-02 3.92e-01
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE 30 1.06e-01 3.01e-01 0.25100 -0.179000 -0.176000 9.06e-02 9.51e-02
REACTOME INACTIVATION OF CDC42 AND RAC1 8 1.06e-01 3.01e-01 0.47500 0.410000 0.240000 4.49e-02 2.40e-01
REACTOME SURFACTANT METABOLISM 29 1.06e-01 3.02e-01 0.19700 -0.164000 0.110000 1.26e-01 3.07e-01
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN 76 1.07e-01 3.02e-01 0.14200 -0.023100 -0.140000 7.28e-01 3.52e-02
REACTOME CHAPERONE MEDIATED AUTOPHAGY 20 1.07e-01 3.02e-01 0.23700 -0.140000 0.191000 2.78e-01 1.40e-01
REACTOME LIPID PARTICLE ORGANIZATION 6 1.07e-01 3.02e-01 0.43100 0.332000 -0.274000 1.59e-01 2.46e-01
REACTOME RESOLUTION OF ABASIC SITES AP SITES 38 1.07e-01 3.03e-01 0.21600 -0.103000 -0.190000 2.72e-01 4.27e-02
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION 183 1.08e-01 3.03e-01 0.10100 -0.074100 -0.069300 8.39e-02 1.06e-01
REACTOME PURINE CATABOLISM 17 1.08e-01 3.05e-01 0.29200 -0.026000 -0.291000 8.53e-01 3.78e-02
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS 24 1.09e-01 3.06e-01 0.27100 -0.130000 -0.238000 2.70e-01 4.38e-02
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING 127 1.10e-01 3.08e-01 0.10500 -0.003440 -0.105000 9.47e-01 4.06e-02
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION 248 1.10e-01 3.08e-01 0.08230 0.029200 0.076900 4.29e-01 3.71e-02
REACTOME SIGNALING BY FGFR1 49 1.11e-01 3.10e-01 0.16500 -0.165000 0.008510 4.58e-02 9.18e-01
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION 6 1.12e-01 3.11e-01 0.43400 0.198000 -0.386000 4.01e-01 1.01e-01
REACTOME O LINKED GLYCOSYLATION 106 1.12e-01 3.11e-01 0.13200 0.088100 0.098100 1.17e-01 8.10e-02
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM 7 1.12e-01 3.12e-01 0.50100 -0.431000 -0.256000 4.83e-02 2.42e-01
REACTOME CELL JUNCTION ORGANIZATION 89 1.12e-01 3.12e-01 0.11400 -0.042800 0.106000 4.85e-01 8.45e-02
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER 54 1.13e-01 3.13e-01 0.17800 -0.077300 -0.160000 3.26e-01 4.20e-02
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS 37 1.13e-01 3.13e-01 0.19300 -0.193000 -0.004890 4.23e-02 9.59e-01
REACTOME ENDOGENOUS STEROLS 26 1.13e-01 3.13e-01 0.21400 -0.205000 0.060600 7.00e-02 5.93e-01
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS 9 1.14e-01 3.13e-01 0.45000 -0.323000 -0.313000 9.32e-02 1.04e-01
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS 37 1.14e-01 3.13e-01 0.18300 -0.035600 0.179000 7.08e-01 5.94e-02
REACTOME HS GAG DEGRADATION 19 1.15e-01 3.15e-01 0.25800 -0.256000 0.033500 5.35e-02 8.01e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING 11 1.16e-01 3.18e-01 0.38600 -0.356000 -0.149000 4.06e-02 3.92e-01
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION 13 1.16e-01 3.18e-01 0.30200 -0.292000 0.078400 6.83e-02 6.24e-01
REACTOME GAP JUNCTION ASSEMBLY 36 1.17e-01 3.18e-01 0.22300 0.145000 0.170000 1.31e-01 7.82e-02
REACTOME EARLY SARS COV 2 INFECTION EVENTS 34 1.18e-01 3.21e-01 0.20700 -0.204000 -0.035400 3.93e-02 7.21e-01
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS 115 1.19e-01 3.24e-01 0.12400 0.097000 0.077800 7.24e-02 1.49e-01
REACTOME NEF AND SIGNAL TRANSDUCTION 8 1.19e-01 3.25e-01 0.46500 0.389000 0.255000 5.66e-02 2.12e-01
REACTOME SIGNALING BY NODAL 21 1.20e-01 3.25e-01 0.24100 -0.238000 0.040500 5.95e-02 7.48e-01
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS 16 1.20e-01 3.25e-01 0.33100 -0.264000 -0.201000 6.79e-02 1.65e-01
REACTOME NCAM1 INTERACTIONS 40 1.21e-01 3.26e-01 0.16200 -0.119000 0.110000 1.91e-01 2.30e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS 32 1.22e-01 3.28e-01 0.19200 -0.043000 0.187000 6.74e-01 6.67e-02
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS 29 1.22e-01 3.28e-01 0.21900 0.218000 0.023000 4.26e-02 8.30e-01
REACTOME SIGNALING BY MAPK MUTANTS 6 1.22e-01 3.29e-01 0.54200 -0.381000 -0.385000 1.06e-01 1.03e-01
REACTOME FORMATION OF AXIAL MESODERM 14 1.22e-01 3.29e-01 0.34200 -0.148000 -0.308000 3.39e-01 4.57e-02
REACTOME CALCINEURIN ACTIVATES NFAT 9 1.22e-01 3.29e-01 0.40400 -0.394000 -0.088900 4.05e-02 6.44e-01
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX 31 1.23e-01 3.29e-01 0.22500 -0.076200 -0.211000 4.63e-01 4.18e-02
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES 34 1.23e-01 3.29e-01 0.20600 -0.202000 -0.039700 4.10e-02 6.89e-01
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION 16 1.24e-01 3.30e-01 0.29000 0.290000 0.019900 4.48e-02 8.91e-01
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS 28 1.24e-01 3.31e-01 0.20500 -0.200000 0.043600 6.68e-02 6.90e-01
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY 12 1.25e-01 3.32e-01 0.38100 -0.283000 -0.255000 8.91e-02 1.27e-01
REACTOME GAP JUNCTION DEGRADATION 12 1.25e-01 3.32e-01 0.37900 -0.302000 -0.229000 7.04e-02 1.70e-01
REACTOME SPHINGOLIPID METABOLISM 84 1.25e-01 3.32e-01 0.14300 -0.083200 -0.116000 1.88e-01 6.55e-02
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM 23 1.25e-01 3.32e-01 0.27000 -0.139000 -0.231000 2.47e-01 5.51e-02
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS 19 1.26e-01 3.32e-01 0.29900 -0.170000 -0.246000 1.98e-01 6.34e-02
REACTOME CLEC7A DECTIN 1 SIGNALING 97 1.26e-01 3.32e-01 0.13300 -0.074200 -0.110000 2.07e-01 6.17e-02
REACTOME COHESIN LOADING ONTO CHROMATIN 8 1.26e-01 3.33e-01 0.46000 -0.379000 -0.261000 6.32e-02 2.01e-01
REACTOME REGULATION OF SIGNALING BY NODAL 10 1.28e-01 3.36e-01 0.32000 -0.239000 0.212000 1.91e-01 2.45e-01
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS 42 1.29e-01 3.39e-01 0.16300 -0.155000 0.048900 8.14e-02 5.84e-01
REACTOME PROTEIN FOLDING 96 1.29e-01 3.39e-01 0.12500 -0.037600 -0.119000 5.24e-01 4.35e-02
REACTOME HEDGEHOG ON STATE 85 1.30e-01 3.40e-01 0.13600 -0.054200 -0.125000 3.88e-01 4.69e-02
REACTOME SIGNALING BY NOTCH1 70 1.30e-01 3.40e-01 0.14700 -0.048700 -0.139000 4.81e-01 4.44e-02
REACTOME CREB PHOSPHORYLATION 6 1.30e-01 3.40e-01 0.41100 -0.261000 0.318000 2.69e-01 1.77e-01
REACTOME MELANIN BIOSYNTHESIS 5 1.31e-01 3.41e-01 0.55600 0.515000 0.210000 4.62e-02 4.17e-01
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS 45 1.31e-01 3.42e-01 0.19200 -0.161000 -0.104000 6.16e-02 2.28e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING 22 1.32e-01 3.42e-01 0.23800 -0.008030 0.237000 9.48e-01 5.39e-02
REACTOME INTERLEUKIN 2 FAMILY SIGNALING 39 1.32e-01 3.42e-01 0.20100 0.181000 0.088100 5.02e-02 3.41e-01
REACTOME TOLL LIKE RECEPTOR CASCADES 158 1.32e-01 3.42e-01 0.09720 -0.092600 -0.029600 4.47e-02 5.21e-01
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT 77 1.32e-01 3.42e-01 0.12400 0.016600 -0.123000 8.02e-01 6.23e-02
REACTOME SENSORY PROCESSING OF SOUND 70 1.33e-01 3.42e-01 0.14400 -0.139000 -0.039700 4.46e-02 5.66e-01
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS 21 1.33e-01 3.42e-01 0.28100 -0.229000 -0.162000 6.89e-02 1.98e-01
REACTOME RECYCLING OF EIF2 GDP 7 1.33e-01 3.42e-01 0.47200 -0.199000 -0.428000 3.62e-01 4.96e-02
REACTOME SIGNALING BY ACTIVIN 15 1.33e-01 3.42e-01 0.33500 -0.226000 -0.248000 1.30e-01 9.66e-02
REACTOME PROLACTIN RECEPTOR SIGNALING 15 1.34e-01 3.42e-01 0.32500 0.148000 0.289000 3.20e-01 5.24e-02
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS 170 1.34e-01 3.42e-01 0.10000 -0.068000 -0.073300 1.26e-01 9.94e-02
REACTOME METABOLISM OF STEROID HORMONES 35 1.34e-01 3.43e-01 0.18100 -0.035800 0.177000 7.14e-01 7.01e-02
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION 22 1.35e-01 3.44e-01 0.26300 -0.099500 -0.244000 4.19e-01 4.78e-02
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 73 1.35e-01 3.44e-01 0.13400 -0.012400 -0.134000 8.54e-01 4.85e-02
REACTOME RAC1 GTPASE CYCLE 173 1.36e-01 3.47e-01 0.08750 0.009130 0.087000 8.36e-01 4.86e-02
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS 81 1.36e-01 3.47e-01 0.12000 -0.119000 0.014800 6.33e-02 8.18e-01
REACTOME DISEASES OF BASE EXCISION REPAIR 5 1.37e-01 3.48e-01 0.51900 -0.084100 -0.513000 7.45e-01 4.72e-02
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA 15 1.37e-01 3.48e-01 0.29200 -0.291000 -0.018500 5.07e-02 9.02e-01
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA 9 1.38e-01 3.50e-01 0.41600 -0.370000 -0.191000 5.48e-02 3.21e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE 5 1.39e-01 3.52e-01 0.55200 0.229000 0.502000 3.75e-01 5.19e-02
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 12 1.40e-01 3.53e-01 0.32700 -0.326000 -0.029300 5.07e-02 8.60e-01
REACTOME INTERLEUKIN 1 FAMILY SIGNALING 147 1.40e-01 3.53e-01 0.09390 -0.009080 -0.093500 8.49e-01 5.05e-02
REACTOME DAP12 SIGNALING 27 1.41e-01 3.53e-01 0.21900 0.217000 0.022000 5.05e-02 8.43e-01
REACTOME AURKA ACTIVATION BY TPX2 69 1.41e-01 3.53e-01 0.15100 -0.076000 -0.131000 2.75e-01 6.05e-02
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS 14 1.41e-01 3.53e-01 0.32200 0.105000 0.304000 4.95e-01 4.86e-02
REACTOME GDP FUCOSE BIOSYNTHESIS 6 1.41e-01 3.53e-01 0.51200 -0.261000 -0.441000 2.68e-01 6.14e-02
REACTOME MTORC1 MEDIATED SIGNALLING 23 1.41e-01 3.53e-01 0.24800 -0.069800 -0.238000 5.63e-01 4.80e-02
REACTOME PRE NOTCH EXPRESSION AND PROCESSING 112 1.42e-01 3.53e-01 0.12000 -0.072700 -0.096100 1.84e-01 7.90e-02
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT 98 1.42e-01 3.54e-01 0.11100 0.002930 -0.111000 9.60e-01 5.80e-02
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS 10 1.42e-01 3.54e-01 0.40400 -0.279000 -0.292000 1.27e-01 1.09e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK 17 1.43e-01 3.55e-01 0.24700 -0.088300 0.230000 5.29e-01 1.00e-01
REACTOME SYNTHESIS OF PC 27 1.44e-01 3.56e-01 0.23000 -0.219000 -0.070300 4.93e-02 5.27e-01
REACTOME MITOTIC TELOPHASE CYTOKINESIS 11 1.44e-01 3.57e-01 0.38400 -0.291000 -0.250000 9.48e-02 1.51e-01
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI 17 1.45e-01 3.58e-01 0.27100 -0.018600 -0.270000 8.95e-01 5.36e-02
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA 5 1.45e-01 3.58e-01 0.56800 -0.426000 -0.376000 9.91e-02 1.45e-01
REACTOME RETINOID CYCLE DISEASE EVENTS 11 1.45e-01 3.58e-01 0.35900 0.341000 0.113000 5.02e-02 5.15e-01
REACTOME PREDNISONE ADME 9 1.46e-01 3.58e-01 0.40500 0.372000 0.162000 5.35e-02 4.01e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION 36 1.46e-01 3.60e-01 0.17400 0.033200 -0.171000 7.30e-01 7.56e-02
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION 20 1.47e-01 3.60e-01 0.22100 -0.187000 0.116000 1.47e-01 3.68e-01
REACTOME INTERLEUKIN 7 SIGNALING 32 1.47e-01 3.60e-01 0.20700 -0.053400 -0.200000 6.01e-01 5.02e-02
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT 23 1.48e-01 3.61e-01 0.22100 0.024500 -0.220000 8.39e-01 6.76e-02
REACTOME DISEASES OF MITOTIC CELL CYCLE 37 1.48e-01 3.61e-01 0.18700 -0.185000 -0.028400 5.20e-02 7.65e-01
REACTOME PTK6 REGULATES CELL CYCLE 6 1.48e-01 3.61e-01 0.51600 -0.349000 -0.380000 1.38e-01 1.07e-01
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM 12 1.48e-01 3.61e-01 0.36200 -0.213000 -0.293000 2.02e-01 7.88e-02
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA 7 1.48e-01 3.61e-01 0.40000 0.047700 -0.397000 8.27e-01 6.88e-02
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP 12 1.49e-01 3.61e-01 0.31900 -0.016200 -0.318000 9.22e-01 5.62e-02
REACTOME SIGNALING BY ALK 26 1.50e-01 3.63e-01 0.24600 -0.148000 -0.197000 1.92e-01 8.28e-02
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY 46 1.50e-01 3.64e-01 0.18000 -0.081300 -0.161000 3.40e-01 5.94e-02
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1 6 1.51e-01 3.64e-01 0.51200 -0.398000 -0.322000 9.10e-02 1.72e-01
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS 16 1.51e-01 3.64e-01 0.25000 -0.092000 0.233000 5.24e-01 1.07e-01
REACTOME OTHER SEMAPHORIN INTERACTIONS 18 1.51e-01 3.64e-01 0.29600 0.196000 0.222000 1.50e-01 1.02e-01
REACTOME ION HOMEOSTASIS 52 1.51e-01 3.64e-01 0.13800 -0.055900 0.126000 4.86e-01 1.16e-01
REACTOME DISEASES OF MISMATCH REPAIR MMR 5 1.52e-01 3.66e-01 0.56200 -0.395000 -0.399000 1.26e-01 1.22e-01
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION 102 1.53e-01 3.67e-01 0.10100 0.026300 -0.097600 6.47e-01 8.87e-02
REACTOME APOPTOTIC EXECUTION PHASE 49 1.54e-01 3.70e-01 0.17100 -0.157000 -0.068000 5.72e-02 4.10e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS 46 1.55e-01 3.71e-01 0.17400 -0.164000 -0.059800 5.50e-02 4.83e-01
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE 11 1.55e-01 3.72e-01 0.35800 0.133000 0.332000 4.44e-01 5.64e-02
REACTOME FCGR ACTIVATION 12 1.56e-01 3.73e-01 0.34200 0.125000 0.318000 4.54e-01 5.63e-02
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE 71 1.56e-01 3.73e-01 0.14500 -0.125000 -0.073800 6.85e-02 2.83e-01
REACTOME ENDOSOMAL VACUOLAR PATHWAY 11 1.57e-01 3.73e-01 0.34100 -0.066300 -0.335000 7.04e-01 5.47e-02
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION 9 1.57e-01 3.74e-01 0.32000 -0.193000 0.256000 3.17e-01 1.84e-01
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING 11 1.58e-01 3.76e-01 0.30100 -0.092900 0.286000 5.94e-01 9.99e-02
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6 32 1.60e-01 3.79e-01 0.21400 -0.186000 -0.107000 6.89e-02 2.96e-01
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER 24 1.61e-01 3.80e-01 0.22000 -0.220000 -0.007530 6.23e-02 9.49e-01
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1 5 1.61e-01 3.80e-01 0.52400 -0.490000 -0.187000 5.79e-02 4.70e-01
REACTOME EPHB MEDIATED FORWARD SIGNALING 41 1.61e-01 3.80e-01 0.18700 -0.168000 -0.081900 6.31e-02 3.64e-01
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES 6 1.61e-01 3.80e-01 0.48400 -0.200000 -0.441000 3.96e-01 6.13e-02
REACTOME FLT3 SIGNALING BY CBL MUTANTS 7 1.62e-01 3.81e-01 0.35900 -0.248000 0.259000 2.55e-01 2.35e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING 16 1.63e-01 3.83e-01 0.25800 -0.032400 0.256000 8.23e-01 7.67e-02
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS 8 1.67e-01 3.91e-01 0.41100 -0.383000 -0.149000 6.07e-02 4.66e-01
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX 13 1.67e-01 3.91e-01 0.33200 -0.289000 -0.164000 7.16e-02 3.07e-01
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION 7 1.68e-01 3.93e-01 0.44900 -0.207000 -0.398000 3.42e-01 6.84e-02
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL 14 1.68e-01 3.93e-01 0.29100 -0.289000 -0.036800 6.13e-02 8.12e-01
REACTOME METAL ION SLC TRANSPORTERS 23 1.69e-01 3.93e-01 0.23700 -0.227000 -0.068100 5.94e-02 5.72e-01
REACTOME PARASITE INFECTION 57 1.70e-01 3.97e-01 0.12600 -0.111000 0.060500 1.48e-01 4.30e-01
REACTOME ROBO RECEPTORS BIND AKAP5 9 1.72e-01 3.99e-01 0.39700 -0.340000 -0.206000 7.74e-02 2.85e-01
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION 8 1.72e-01 3.99e-01 0.38500 0.057100 0.381000 7.80e-01 6.21e-02
REACTOME SIGNALING BY WNT IN CANCER 32 1.73e-01 4.02e-01 0.20700 -0.090300 -0.186000 3.77e-01 6.84e-02
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING 17 1.74e-01 4.03e-01 0.22800 -0.193000 0.121000 1.68e-01 3.86e-01
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME 11 1.74e-01 4.03e-01 0.35800 -0.305000 -0.189000 8.01e-02 2.79e-01
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS 84 1.75e-01 4.03e-01 0.10300 -0.090400 0.050100 1.52e-01 4.27e-01
REACTOME NUCLEOTIDE BIOSYNTHESIS 14 1.75e-01 4.03e-01 0.32300 -0.214000 -0.242000 1.67e-01 1.17e-01
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING 9 1.75e-01 4.03e-01 0.38300 -0.144000 -0.355000 4.56e-01 6.51e-02
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 12 1.75e-01 4.03e-01 0.28600 -0.280000 0.059600 9.33e-02 7.21e-01
REACTOME DEVELOPMENTAL BIOLOGY 1103 1.76e-01 4.04e-01 0.03280 -0.002000 -0.032700 9.11e-01 6.77e-02
REACTOME PYRUVATE METABOLISM 29 1.76e-01 4.04e-01 0.21500 -0.196000 -0.088900 6.78e-02 4.07e-01
REACTOME REGULATION OF BACH1 ACTIVITY 11 1.77e-01 4.04e-01 0.28100 -0.227000 0.165000 1.92e-01 3.42e-01
REACTOME COLLAGEN FORMATION 87 1.77e-01 4.06e-01 0.10300 -0.096600 0.036100 1.19e-01 5.60e-01
REACTOME ZINC TRANSPORTERS 15 1.78e-01 4.06e-01 0.26800 -0.268000 -0.000219 7.23e-02 9.99e-01
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS 20 1.78e-01 4.06e-01 0.26500 -0.141000 -0.224000 2.74e-01 8.32e-02
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION 9 1.78e-01 4.06e-01 0.40000 -0.265000 -0.300000 1.68e-01 1.20e-01
REACTOME RSK ACTIVATION 5 1.79e-01 4.07e-01 0.42200 -0.184000 0.380000 4.76e-01 1.41e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS 5 1.80e-01 4.08e-01 0.53600 -0.368000 -0.389000 1.54e-01 1.32e-01
REACTOME TRANSLESION SYNTHESIS BY POLH 19 1.81e-01 4.11e-01 0.26600 -0.237000 -0.119000 7.32e-02 3.68e-01
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS 5 1.82e-01 4.11e-01 0.50800 -0.471000 -0.190000 6.80e-02 4.62e-01
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES 9 1.82e-01 4.11e-01 0.33100 -0.050000 0.327000 7.95e-01 8.93e-02
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING 30 1.82e-01 4.11e-01 0.17700 -0.171000 0.045400 1.04e-01 6.67e-01
REACTOME PROCESSING OF SMDT1 16 1.85e-01 4.15e-01 0.23900 0.072600 -0.228000 6.15e-01 1.14e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX 19 1.85e-01 4.15e-01 0.27000 -0.221000 -0.155000 9.51e-02 2.41e-01
REACTOME TRANSLESION SYNTHESIS BY POLK 17 1.85e-01 4.15e-01 0.26600 -0.257000 -0.066200 6.61e-02 6.36e-01
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING 9 1.85e-01 4.15e-01 0.31800 -0.300000 0.103000 1.19e-01 5.92e-01
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY 10 1.85e-01 4.15e-01 0.29300 -0.255000 0.146000 1.63e-01 4.26e-01
REACTOME INTERLEUKIN 37 SIGNALING 21 1.85e-01 4.15e-01 0.21000 -0.201000 0.059500 1.11e-01 6.37e-01
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT 101 1.86e-01 4.15e-01 0.10200 0.002560 -0.101000 9.65e-01 7.81e-02
REACTOME RAB REGULATION OF TRAFFICKING 111 1.86e-01 4.15e-01 0.09990 -0.099400 -0.009370 7.04e-02 8.65e-01
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN 13 1.86e-01 4.16e-01 0.32900 -0.223000 -0.242000 1.63e-01 1.32e-01
REACTOME REGULATION OF BETA CELL DEVELOPMENT 41 1.87e-01 4.16e-01 0.18500 -0.124000 -0.137000 1.68e-01 1.28e-01
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY 29 1.87e-01 4.16e-01 0.19900 -0.196000 -0.034900 6.81e-02 7.45e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS 16 1.87e-01 4.16e-01 0.29600 -0.224000 -0.193000 1.21e-01 1.82e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI 26 1.87e-01 4.16e-01 0.18300 -0.164000 0.080900 1.48e-01 4.75e-01
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES 26 1.88e-01 4.16e-01 0.23200 -0.155000 -0.173000 1.73e-01 1.27e-01
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION 21 1.89e-01 4.18e-01 0.23200 -0.036300 -0.229000 7.73e-01 6.92e-02
REACTOME O LINKED GLYCOSYLATION OF MUCINS 59 1.90e-01 4.19e-01 0.15200 0.127000 0.083300 9.21e-02 2.69e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 122 1.92e-01 4.23e-01 0.10300 0.093400 0.042400 7.49e-02 4.18e-01
REACTOME CELL CELL JUNCTION ORGANIZATION 64 1.92e-01 4.23e-01 0.12000 -0.030800 0.116000 6.70e-01 1.10e-01
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON 17 1.92e-01 4.23e-01 0.26400 -0.254000 -0.071300 6.95e-02 6.11e-01
REACTOME METALLOTHIONEINS BIND METALS 11 1.93e-01 4.24e-01 0.31500 -0.313000 -0.039400 7.23e-02 8.21e-01
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE 52 1.93e-01 4.24e-01 0.16100 -0.132000 -0.092000 9.88e-02 2.51e-01
REACTOME DUAL INCISION IN GG NER 39 1.94e-01 4.25e-01 0.18800 -0.132000 -0.133000 1.52e-01 1.50e-01
REACTOME SIGNALING BY HEDGEHOG 148 1.95e-01 4.28e-01 0.09650 -0.065500 -0.070900 1.69e-01 1.37e-01
REACTOME EGFR DOWNREGULATION 29 1.96e-01 4.29e-01 0.17500 -0.050000 0.168000 6.41e-01 1.17e-01
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B 7 1.96e-01 4.29e-01 0.33900 -0.239000 0.241000 2.73e-01 2.70e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM 50 1.98e-01 4.30e-01 0.15400 -0.147000 -0.047900 7.25e-02 5.58e-01
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2 60 1.98e-01 4.30e-01 0.15000 -0.119000 -0.091000 1.11e-01 2.23e-01
REACTOME SERINE BIOSYNTHESIS 9 1.98e-01 4.30e-01 0.32500 0.040900 -0.322000 8.32e-01 9.43e-02
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING 13 1.98e-01 4.30e-01 0.31600 -0.274000 -0.158000 8.75e-02 3.25e-01
REACTOME CROSSLINKING OF COLLAGEN FIBRILS 16 1.98e-01 4.30e-01 0.28600 -0.150000 -0.243000 2.98e-01 9.19e-02
REACTOME REPRODUCTION 136 1.99e-01 4.31e-01 0.09130 -0.019300 -0.089200 6.97e-01 7.26e-02
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL 15 1.99e-01 4.31e-01 0.30000 0.209000 0.216000 1.61e-01 1.48e-01
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES 27 2.00e-01 4.33e-01 0.22200 -0.176000 -0.136000 1.14e-01 2.21e-01
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS 52 2.02e-01 4.34e-01 0.16100 -0.121000 -0.105000 1.30e-01 1.90e-01
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES 16 2.02e-01 4.34e-01 0.22300 -0.154000 0.161000 2.85e-01 2.66e-01
REACTOME MISCELLANEOUS SUBSTRATES 12 2.02e-01 4.34e-01 0.26300 -0.116000 0.236000 4.87e-01 1.57e-01
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS 9 2.02e-01 4.34e-01 0.30100 -0.263000 0.147000 1.71e-01 4.46e-01
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING 6 2.02e-01 4.35e-01 0.36500 -0.298000 0.211000 2.06e-01 3.71e-01
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO 10 2.04e-01 4.38e-01 0.32200 0.029900 0.321000 8.70e-01 7.89e-02
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE 5 2.04e-01 4.38e-01 0.49400 -0.451000 -0.202000 8.04e-02 4.35e-01
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL 13 2.06e-01 4.39e-01 0.24600 -0.162000 0.185000 3.13e-01 2.48e-01
REACTOME SIGNALING BY NOTCH2 32 2.06e-01 4.39e-01 0.20300 -0.139000 -0.149000 1.75e-01 1.45e-01
REACTOME TERMINAL PATHWAY OF COMPLEMENT 7 2.06e-01 4.39e-01 0.38100 0.380000 0.023100 8.15e-02 9.16e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS 62 2.07e-01 4.41e-01 0.12800 -0.009150 -0.128000 9.01e-01 8.14e-02
REACTOME GLYCOSAMINOGLYCAN METABOLISM 114 2.09e-01 4.44e-01 0.09270 -0.092700 0.000217 8.73e-02 9.97e-01
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION 10 2.09e-01 4.44e-01 0.33800 -0.100000 -0.323000 5.82e-01 7.73e-02
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION 15 2.09e-01 4.44e-01 0.26800 -0.263000 -0.048900 7.78e-02 7.43e-01
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA 50 2.10e-01 4.45e-01 0.15900 -0.136000 -0.081200 9.57e-02 3.20e-01
REACTOME INTERLEUKIN 20 FAMILY SIGNALING 26 2.11e-01 4.46e-01 0.21800 0.193000 0.101000 8.89e-02 3.73e-01
REACTOME SIGNALING BY ERBB4 57 2.11e-01 4.47e-01 0.11700 -0.068700 0.094700 3.70e-01 2.16e-01
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS 50 2.12e-01 4.47e-01 0.15000 -0.044000 -0.144000 5.91e-01 7.84e-02
REACTOME TRIGLYCERIDE CATABOLISM 19 2.13e-01 4.48e-01 0.26100 -0.170000 -0.198000 2.00e-01 1.36e-01
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY 16 2.14e-01 4.48e-01 0.25200 -0.251000 -0.028100 8.23e-02 8.46e-01
REACTOME MATURATION OF PROTEIN 3A 9 2.14e-01 4.48e-01 0.35600 0.337000 0.117000 8.03e-02 5.42e-01
REACTOME OPSINS 7 2.14e-01 4.48e-01 0.42900 0.328000 0.276000 1.33e-01 2.06e-01
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION 7 2.14e-01 4.48e-01 0.39000 0.383000 0.074500 7.97e-02 7.33e-01
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY 10 2.14e-01 4.48e-01 0.28000 -0.141000 0.242000 4.39e-01 1.85e-01
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE 17 2.14e-01 4.48e-01 0.23900 -0.239000 -0.004080 8.84e-02 9.77e-01
REACTOME ECM PROTEOGLYCANS 72 2.14e-01 4.48e-01 0.12300 0.028800 0.120000 6.73e-01 7.92e-02
REACTOME ACTIVATION OF SMO 18 2.15e-01 4.48e-01 0.23600 -0.235000 -0.019400 8.42e-02 8.86e-01
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY 11 2.15e-01 4.48e-01 0.30000 0.017000 0.299000 9.22e-01 8.59e-02
REACTOME G PROTEIN MEDIATED EVENTS 52 2.16e-01 4.49e-01 0.12100 -0.088700 0.082400 2.69e-01 3.04e-01
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX 15 2.16e-01 4.49e-01 0.23400 -0.220000 0.080300 1.41e-01 5.90e-01
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION 30 2.16e-01 4.49e-01 0.16400 -0.064800 0.150000 5.39e-01 1.54e-01
REACTOME HEDGEHOG OFF STATE 111 2.17e-01 4.50e-01 0.09520 -0.009200 -0.094700 8.67e-01 8.47e-02
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 18 2.17e-01 4.50e-01 0.24700 -0.066800 -0.238000 6.24e-01 8.07e-02
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION 30 2.18e-01 4.50e-01 0.18200 -0.017000 -0.182000 8.72e-01 8.51e-02
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS 14 2.20e-01 4.55e-01 0.29900 -0.184000 -0.236000 2.34e-01 1.26e-01
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION 10 2.20e-01 4.55e-01 0.31200 0.019600 0.311000 9.15e-01 8.82e-02
REACTOME CDC42 GTPASE CYCLE 144 2.21e-01 4.55e-01 0.08620 0.019600 0.083900 6.84e-01 8.23e-02
REACTOME TRIGLYCERIDE METABOLISM 31 2.22e-01 4.56e-01 0.19900 -0.168000 -0.106000 1.06e-01 3.05e-01
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS 5 2.24e-01 4.61e-01 0.48700 -0.232000 -0.428000 3.69e-01 9.73e-02
REACTOME MINERALOCORTICOID BIOSYNTHESIS 6 2.25e-01 4.61e-01 0.37200 -0.088100 0.362000 7.09e-01 1.25e-01
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION 5 2.25e-01 4.61e-01 0.48200 -0.209000 -0.435000 4.19e-01 9.23e-02
REACTOME NETRIN MEDIATED REPULSION SIGNALS 8 2.25e-01 4.61e-01 0.30600 -0.255000 0.170000 2.11e-01 4.06e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES 27 2.25e-01 4.61e-01 0.18300 -0.183000 0.008420 9.94e-02 9.40e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION 21 2.26e-01 4.62e-01 0.22800 -0.071000 -0.217000 5.73e-01 8.55e-02
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE 16 2.27e-01 4.62e-01 0.23100 -0.040100 0.227000 7.81e-01 1.16e-01
REACTOME CALCITONIN LIKE LIGAND RECEPTORS 10 2.28e-01 4.64e-01 0.35200 -0.253000 -0.245000 1.66e-01 1.80e-01
REACTOME MISMATCH REPAIR 15 2.28e-01 4.64e-01 0.28500 -0.228000 -0.172000 1.26e-01 2.49e-01
REACTOME MAP2K AND MAPK ACTIVATION 38 2.28e-01 4.64e-01 0.14000 -0.117000 0.077700 2.14e-01 4.07e-01
REACTOME G2 PHASE 5 2.29e-01 4.64e-01 0.45100 -0.086500 -0.443000 7.38e-01 8.65e-02
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY 10 2.29e-01 4.64e-01 0.28300 -0.269000 0.086000 1.40e-01 6.38e-01
REACTOME PINK1 PRKN MEDIATED MITOPHAGY 22 2.29e-01 4.64e-01 0.22800 -0.096700 -0.206000 4.32e-01 9.37e-02
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES 91 2.31e-01 4.67e-01 0.10700 -0.025500 -0.104000 6.75e-01 8.68e-02
REACTOME NEGATIVE REGULATION OF MET ACTIVITY 20 2.32e-01 4.67e-01 0.19400 -0.172000 0.089900 1.83e-01 4.87e-01
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY 7 2.32e-01 4.67e-01 0.32700 0.288000 -0.156000 1.88e-01 4.74e-01
REACTOME NUCLEAR SIGNALING BY ERBB4 32 2.32e-01 4.68e-01 0.15100 -0.111000 0.101000 2.76e-01 3.21e-01
REACTOME REGULATED NECROSIS 57 2.34e-01 4.71e-01 0.11700 -0.039700 0.110000 6.05e-01 1.51e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL 24 2.35e-01 4.71e-01 0.22300 0.129000 0.182000 2.76e-01 1.22e-01
REACTOME GP1B IX V ACTIVATION SIGNALLING 11 2.35e-01 4.72e-01 0.25600 -0.174000 0.187000 3.17e-01 2.83e-01
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION 15 2.37e-01 4.74e-01 0.25400 -0.252000 -0.037100 9.16e-02 8.03e-01
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY 95 2.40e-01 4.80e-01 0.09610 0.003620 -0.096000 9.51e-01 1.06e-01
REACTOME SIGNALING BY FGFR4 40 2.40e-01 4.81e-01 0.15300 -0.152000 -0.015000 9.56e-02 8.69e-01
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS 5 2.42e-01 4.83e-01 0.44500 -0.435000 -0.092400 9.22e-02 7.20e-01
REACTOME INSULIN RECEPTOR RECYCLING 28 2.42e-01 4.83e-01 0.16900 -0.164000 0.037700 1.32e-01 7.30e-01
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS 43 2.42e-01 4.83e-01 0.16500 -0.132000 -0.099200 1.34e-01 2.61e-01
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A 26 2.43e-01 4.83e-01 0.17200 -0.163000 0.053600 1.50e-01 6.36e-01
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP 41 2.43e-01 4.83e-01 0.17000 -0.122000 -0.119000 1.77e-01 1.89e-01
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS 14 2.44e-01 4.83e-01 0.22400 0.149000 -0.167000 3.34e-01 2.80e-01
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE 17 2.44e-01 4.83e-01 0.22500 -0.224000 0.011500 1.09e-01 9.34e-01
REACTOME FCERI MEDIATED CA 2 MOBILIZATION 30 2.45e-01 4.84e-01 0.18600 0.060600 0.176000 5.66e-01 9.46e-02
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS 15 2.45e-01 4.84e-01 0.27300 0.239000 0.132000 1.09e-01 3.75e-01
REACTOME FORMATION OF LATERAL PLATE MESODERM 5 2.45e-01 4.84e-01 0.48300 -0.299000 -0.379000 2.46e-01 1.42e-01
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA 15 2.47e-01 4.87e-01 0.22300 -0.208000 0.080300 1.64e-01 5.90e-01
REACTOME GOLGI TO ER RETROGRADE TRANSPORT 132 2.48e-01 4.89e-01 0.09430 -0.063600 -0.069700 2.07e-01 1.67e-01
REACTOME REGULATION OF FZD BY UBIQUITINATION 21 2.49e-01 4.90e-01 0.23100 -0.198000 -0.120000 1.17e-01 3.40e-01
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS 13 2.50e-01 4.91e-01 0.29200 -0.143000 -0.254000 3.71e-01 1.12e-01
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1 16 2.51e-01 4.92e-01 0.26600 -0.147000 -0.222000 3.10e-01 1.25e-01
REACTOME OPIOID SIGNALLING 88 2.52e-01 4.95e-01 0.09980 -0.099700 -0.003210 1.06e-01 9.59e-01
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD 7 2.54e-01 4.96e-01 0.33500 -0.329000 0.060300 1.32e-01 7.82e-01
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM 7 2.54e-01 4.96e-01 0.31500 -0.269000 0.165000 2.18e-01 4.50e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE 20 2.54e-01 4.96e-01 0.23900 -0.154000 -0.183000 2.33e-01 1.57e-01
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS 18 2.56e-01 4.99e-01 0.20600 0.201000 -0.046700 1.41e-01 7.32e-01
REACTOME MET RECEPTOR RECYCLING 10 2.56e-01 4.99e-01 0.31100 -0.074900 -0.302000 6.82e-01 9.87e-02
REACTOME ARACHIDONATE PRODUCTION FROM DAG 5 2.56e-01 4.99e-01 0.37900 -0.147000 0.349000 5.70e-01 1.77e-01
REACTOME ERYTHROPOIETIN ACTIVATES STAT5 7 2.57e-01 4.99e-01 0.31000 -0.224000 0.215000 3.05e-01 3.24e-01
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM 7 2.57e-01 5.00e-01 0.37600 0.110000 0.359000 6.14e-01 9.99e-02
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING 25 2.58e-01 5.01e-01 0.16800 -0.073800 0.150000 5.23e-01 1.93e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES 14 2.59e-01 5.02e-01 0.23200 -0.225000 0.055100 1.44e-01 7.21e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS 26 2.60e-01 5.03e-01 0.17300 -0.027600 0.171000 8.07e-01 1.32e-01
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS 7 2.60e-01 5.03e-01 0.39900 -0.240000 -0.319000 2.71e-01 1.44e-01
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS 9 2.61e-01 5.04e-01 0.34600 -0.175000 -0.299000 3.65e-01 1.20e-01
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 22 2.62e-01 5.05e-01 0.22500 -0.140000 -0.176000 2.56e-01 1.52e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM 36 2.62e-01 5.05e-01 0.15200 -0.152000 0.002820 1.15e-01 9.77e-01
REACTOME COENZYME A BIOSYNTHESIS 8 2.65e-01 5.10e-01 0.29600 0.112000 -0.274000 5.85e-01 1.79e-01
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES 40 2.66e-01 5.11e-01 0.15700 -0.148000 -0.053400 1.06e-01 5.59e-01
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX 38 2.67e-01 5.13e-01 0.16800 -0.142000 -0.088700 1.29e-01 3.44e-01
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 98 2.68e-01 5.15e-01 0.10600 -0.083900 -0.064300 1.51e-01 2.72e-01
REACTOME RHOT1 GTPASE CYCLE 5 2.69e-01 5.15e-01 0.42000 -0.058900 -0.415000 8.20e-01 1.08e-01
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS 6 2.69e-01 5.15e-01 0.40700 -0.152000 -0.378000 5.20e-01 1.09e-01
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL 14 2.70e-01 5.15e-01 0.24400 -0.244000 -0.008700 1.14e-01 9.55e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES 51 2.70e-01 5.16e-01 0.13600 0.036800 0.131000 6.49e-01 1.06e-01
REACTOME LIGAND RECEPTOR INTERACTIONS 8 2.71e-01 5.17e-01 0.37000 -0.255000 -0.268000 2.12e-01 1.89e-01
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS 25 2.71e-01 5.17e-01 0.20700 0.118000 0.170000 3.08e-01 1.41e-01
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS 14 2.72e-01 5.17e-01 0.24200 0.004870 0.242000 9.75e-01 1.17e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS 15 2.72e-01 5.17e-01 0.23500 -0.235000 -0.008640 1.16e-01 9.54e-01
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION 21 2.72e-01 5.17e-01 0.22800 0.167000 0.155000 1.85e-01 2.19e-01
REACTOME METABOLISM OF AMINE DERIVED HORMONES 17 2.73e-01 5.17e-01 0.20900 -0.038700 0.205000 7.82e-01 1.43e-01
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY 13 2.74e-01 5.19e-01 0.22600 -0.200000 0.105000 2.11e-01 5.11e-01
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION 41 2.75e-01 5.21e-01 0.14900 -0.145000 -0.035300 1.08e-01 6.96e-01
REACTOME PENTOSE PHOSPHATE PATHWAY 11 2.76e-01 5.21e-01 0.30800 -0.165000 -0.261000 3.45e-01 1.34e-01
REACTOME INTERLEUKIN 35 SIGNALLING 12 2.76e-01 5.21e-01 0.23600 0.098900 -0.215000 5.53e-01 1.98e-01
REACTOME NICOTINATE METABOLISM 31 2.77e-01 5.22e-01 0.18600 0.137000 0.127000 1.87e-01 2.23e-01
REACTOME ALPHA OXIDATION OF PHYTANATE 6 2.77e-01 5.22e-01 0.42300 -0.283000 -0.315000 2.30e-01 1.82e-01
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT 18 2.79e-01 5.24e-01 0.24400 -0.164000 -0.180000 2.28e-01 1.86e-01
REACTOME ATTACHMENT AND ENTRY 16 2.81e-01 5.28e-01 0.25700 -0.202000 -0.159000 1.63e-01 2.71e-01
REACTOME IKBA VARIANT LEADS TO EDA ID 6 2.81e-01 5.28e-01 0.41500 -0.347000 -0.229000 1.41e-01 3.32e-01
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION 23 2.82e-01 5.28e-01 0.21500 0.147000 0.157000 2.23e-01 1.93e-01
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF 17 2.82e-01 5.29e-01 0.24100 -0.107000 -0.216000 4.46e-01 1.23e-01
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS 5 2.83e-01 5.29e-01 0.35700 -0.300000 0.194000 2.45e-01 4.54e-01
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE 37 2.84e-01 5.30e-01 0.16100 0.062100 0.149000 5.13e-01 1.17e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS 14 2.84e-01 5.30e-01 0.21100 -0.156000 0.142000 3.11e-01 3.57e-01
REACTOME PHENYLALANINE AND TYROSINE METABOLISM 11 2.85e-01 5.31e-01 0.30900 0.220000 0.217000 2.07e-01 2.12e-01
REACTOME OAS ANTIVIRAL RESPONSE 8 2.87e-01 5.32e-01 0.27900 0.221000 -0.170000 2.78e-01 4.05e-01
REACTOME DNA STRAND ELONGATION 31 2.87e-01 5.32e-01 0.15100 0.031900 -0.147000 7.59e-01 1.56e-01
REACTOME GLYCOGEN METABOLISM 21 2.87e-01 5.32e-01 0.18200 -0.176000 0.045700 1.63e-01 7.17e-01
REACTOME G2 M DNA REPLICATION CHECKPOINT 5 2.87e-01 5.32e-01 0.44800 -0.227000 -0.386000 3.80e-01 1.35e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS 29 2.87e-01 5.32e-01 0.17000 -0.023700 -0.168000 8.26e-01 1.17e-01
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX 41 2.89e-01 5.34e-01 0.12300 -0.093700 0.079400 3.00e-01 3.79e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 13 2.89e-01 5.34e-01 0.21800 0.150000 -0.158000 3.49e-01 3.25e-01
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS 31 2.90e-01 5.34e-01 0.17200 0.053800 0.163000 6.04e-01 1.16e-01
REACTOME FIBRONECTIN MATRIX FORMATION 6 2.90e-01 5.34e-01 0.33500 -0.099500 0.320000 6.73e-01 1.75e-01
REACTOME POLYMERASE SWITCHING 13 2.91e-01 5.37e-01 0.24700 -0.013600 -0.246000 9.32e-01 1.24e-01
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS 7 2.92e-01 5.37e-01 0.32300 0.322000 -0.030900 1.40e-01 8.87e-01
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS 8 2.92e-01 5.37e-01 0.33000 -0.079900 -0.320000 6.95e-01 1.17e-01
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES 101 2.93e-01 5.37e-01 0.08040 -0.030100 0.074600 6.02e-01 1.95e-01
REACTOME RHOH GTPASE CYCLE 37 2.93e-01 5.37e-01 0.16500 -0.137000 -0.091300 1.49e-01 3.36e-01
REACTOME SCAVENGING OF HEME FROM PLASMA 12 2.94e-01 5.38e-01 0.28900 0.239000 0.163000 1.52e-01 3.28e-01
REACTOME CHYLOMICRON REMODELING 10 2.96e-01 5.41e-01 0.24700 -0.196000 0.150000 2.83e-01 4.12e-01
REACTOME PI 3K CASCADE FGFR1 21 2.96e-01 5.41e-01 0.21600 -0.187000 -0.108000 1.39e-01 3.93e-01
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT 6 2.98e-01 5.44e-01 0.34100 -0.337000 0.054000 1.53e-01 8.19e-01
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX 36 3.00e-01 5.46e-01 0.14000 0.139000 -0.018500 1.50e-01 8.47e-01
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS 43 3.00e-01 5.46e-01 0.11800 -0.082800 0.084000 3.48e-01 3.40e-01
REACTOME INTERLEUKIN 12 SIGNALING 45 3.00e-01 5.46e-01 0.11500 0.083000 -0.079900 3.36e-01 3.54e-01
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE 11 3.01e-01 5.46e-01 0.30300 -0.209000 -0.219000 2.30e-01 2.09e-01
REACTOME SIGNALING BY FGFR1 IN DISEASE 38 3.01e-01 5.46e-01 0.15000 -0.145000 -0.035600 1.21e-01 7.04e-01
REACTOME AMINE LIGAND BINDING RECEPTORS 40 3.02e-01 5.49e-01 0.14800 -0.141000 -0.045200 1.23e-01 6.21e-01
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM 13 3.03e-01 5.49e-01 0.25800 -0.074200 -0.247000 6.43e-01 1.23e-01
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE 9 3.03e-01 5.49e-01 0.32700 -0.280000 -0.170000 1.46e-01 3.78e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS 8 3.05e-01 5.51e-01 0.27100 -0.183000 0.201000 3.71e-01 3.26e-01
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA 5 3.05e-01 5.51e-01 0.41100 -0.398000 -0.105000 1.23e-01 6.85e-01
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION 9 3.06e-01 5.53e-01 0.26800 -0.256000 0.077400 1.83e-01 6.88e-01
REACTOME RUNX3 REGULATES WNT SIGNALING 8 3.07e-01 5.53e-01 0.31700 -0.054200 -0.313000 7.91e-01 1.26e-01
REACTOME TRP CHANNELS 27 3.08e-01 5.54e-01 0.15600 -0.037300 0.151000 7.37e-01 1.73e-01
REACTOME CIPROFLOXACIN ADME 5 3.08e-01 5.54e-01 0.36500 -0.358000 0.072500 1.66e-01 7.79e-01
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE 7 3.08e-01 5.54e-01 0.37400 -0.238000 -0.288000 2.75e-01 1.86e-01
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 687 3.10e-01 5.56e-01 0.02970 0.023200 -0.018500 3.02e-01 4.08e-01
REACTOME PI3K AKT ACTIVATION 9 3.10e-01 5.56e-01 0.29800 -0.052800 -0.294000 7.84e-01 1.27e-01
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER 15 3.10e-01 5.56e-01 0.25400 -0.203000 -0.153000 1.74e-01 3.05e-01
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION 20 3.11e-01 5.56e-01 0.21700 -0.109000 -0.187000 4.00e-01 1.47e-01
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS 19 3.12e-01 5.57e-01 0.20000 -0.199000 -0.018300 1.32e-01 8.90e-01
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2 8 3.13e-01 5.58e-01 0.33800 -0.153000 -0.301000 4.53e-01 1.40e-01
REACTOME OTHER INTERLEUKIN SIGNALING 24 3.13e-01 5.58e-01 0.15800 -0.139000 0.074600 2.39e-01 5.27e-01
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION 9 3.15e-01 5.60e-01 0.31800 -0.143000 -0.284000 4.58e-01 1.41e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY 51 3.16e-01 5.62e-01 0.10600 -0.069700 0.079900 3.89e-01 3.23e-01
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES 7 3.16e-01 5.62e-01 0.31700 -0.010200 0.317000 9.63e-01 1.46e-01
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER 25 3.16e-01 5.62e-01 0.16700 -0.167000 0.008080 1.48e-01 9.44e-01
REACTOME RECEPTOR MEDIATED MITOPHAGY 10 3.18e-01 5.64e-01 0.27100 -0.270000 -0.014100 1.39e-01 9.39e-01
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES 34 3.18e-01 5.64e-01 0.13200 -0.057600 0.119000 5.61e-01 2.30e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING 23 3.19e-01 5.64e-01 0.19200 -0.181000 -0.062700 1.32e-01 6.02e-01
REACTOME LYSOSOME VESICLE BIOGENESIS 33 3.20e-01 5.65e-01 0.15800 -0.152000 -0.042600 1.31e-01 6.72e-01
REACTOME POTASSIUM CHANNELS 102 3.20e-01 5.65e-01 0.07650 -0.069600 0.031800 2.25e-01 5.79e-01
REACTOME FORMATION OF PARAXIAL MESODERM 22 3.21e-01 5.65e-01 0.16100 0.126000 -0.099900 3.08e-01 4.17e-01
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY 5 3.21e-01 5.65e-01 0.43200 -0.245000 -0.356000 3.43e-01 1.69e-01
REACTOME POTENTIAL THERAPEUTICS FOR SARS 92 3.21e-01 5.66e-01 0.09800 -0.088800 -0.041400 1.41e-01 4.92e-01
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY 30 3.22e-01 5.66e-01 0.16200 -0.159000 -0.031400 1.33e-01 7.66e-01
REACTOME RHOG GTPASE CYCLE 71 3.22e-01 5.66e-01 0.11300 0.055400 0.098500 4.20e-01 1.51e-01
REACTOME RHO GTPASE CYCLE 422 3.24e-01 5.67e-01 0.04190 -0.041900 -0.002660 1.41e-01 9.25e-01
REACTOME SIALIC ACID METABOLISM 33 3.24e-01 5.67e-01 0.14300 0.143000 -0.011000 1.56e-01 9.13e-01
REACTOME PURINE SALVAGE 12 3.24e-01 5.67e-01 0.27800 -0.161000 -0.227000 3.35e-01 1.74e-01
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION 6 3.25e-01 5.67e-01 0.30600 -0.247000 0.181000 2.95e-01 4.41e-01
REACTOME GPER1 SIGNALING 44 3.25e-01 5.67e-01 0.12000 -0.117000 0.025900 1.79e-01 7.66e-01
REACTOME MIRO GTPASE CYCLE 8 3.25e-01 5.67e-01 0.32700 -0.126000 -0.302000 5.37e-01 1.39e-01
REACTOME RND1 GTPASE CYCLE 41 3.26e-01 5.68e-01 0.13900 -0.034300 -0.135000 7.04e-01 1.34e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS 5 3.27e-01 5.69e-01 0.37200 -0.004320 0.372000 9.87e-01 1.50e-01
REACTOME RECYCLING PATHWAY OF L1 43 3.27e-01 5.69e-01 0.11600 -0.050900 0.104000 5.63e-01 2.36e-01
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE 10 3.27e-01 5.69e-01 0.27300 -0.271000 -0.037200 1.38e-01 8.39e-01
REACTOME PROTEIN METHYLATION 17 3.29e-01 5.70e-01 0.23000 -0.118000 -0.197000 3.98e-01 1.60e-01
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE 20 3.29e-01 5.70e-01 0.20500 0.073400 0.191000 5.70e-01 1.39e-01
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX 29 3.30e-01 5.72e-01 0.17900 -0.126000 -0.127000 2.38e-01 2.38e-01
REACTOME TRANSPORT AND SYNTHESIS OF PAPS 6 3.32e-01 5.73e-01 0.37400 -0.346000 -0.142000 1.42e-01 5.47e-01
REACTOME INTESTINAL ABSORPTION 5 3.32e-01 5.73e-01 0.42900 0.277000 0.328000 2.84e-01 2.05e-01
REACTOME PLATELET AGGREGATION PLUG FORMATION 39 3.32e-01 5.73e-01 0.11800 -0.080400 0.087000 3.85e-01 3.47e-01
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN 15 3.32e-01 5.73e-01 0.22600 0.046900 0.221000 7.53e-01 1.38e-01
REACTOME SYNTHESIS OF LIPOXINS LX 6 3.33e-01 5.74e-01 0.31500 0.300000 -0.096300 2.03e-01 6.83e-01
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS 12 3.34e-01 5.75e-01 0.22900 0.038900 -0.226000 8.16e-01 1.76e-01
REACTOME SIGNALING BY INSULIN RECEPTOR 78 3.35e-01 5.75e-01 0.09140 -0.091000 0.008940 1.65e-01 8.91e-01
REACTOME PROTEIN REPAIR 6 3.35e-01 5.75e-01 0.37500 -0.155000 -0.342000 5.11e-01 1.47e-01
REACTOME NRAGE SIGNALS DEATH THROUGH JNK 53 3.36e-01 5.75e-01 0.11600 0.116000 0.010500 1.45e-01 8.94e-01
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION 8 3.36e-01 5.75e-01 0.26000 -0.168000 0.199000 4.10e-01 3.31e-01
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN 18 3.37e-01 5.75e-01 0.19500 -0.003500 -0.195000 9.79e-01 1.52e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM 39 3.37e-01 5.75e-01 0.13000 0.007090 -0.130000 9.39e-01 1.60e-01
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER 18 3.37e-01 5.75e-01 0.19900 -0.198000 -0.020800 1.45e-01 8.79e-01
REACTOME VITAMIN C ASCORBATE METABOLISM 8 3.37e-01 5.75e-01 0.26000 -0.198000 0.168000 3.31e-01 4.11e-01
REACTOME AQUAPORIN MEDIATED TRANSPORT 51 3.38e-01 5.75e-01 0.10300 -0.074300 0.071100 3.59e-01 3.80e-01
REACTOME RET SIGNALING 40 3.38e-01 5.75e-01 0.15100 -0.113000 -0.099700 2.16e-01 2.76e-01
REACTOME MEIOTIC SYNAPSIS 73 3.39e-01 5.76e-01 0.10600 -0.037500 -0.098800 5.80e-01 1.45e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING 14 3.39e-01 5.76e-01 0.25000 0.134000 0.211000 3.84e-01 1.71e-01
REACTOME INTEGRIN CELL SURFACE INTERACTIONS 82 3.40e-01 5.77e-01 0.09730 0.025500 0.093900 6.90e-01 1.42e-01
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION 12 3.40e-01 5.77e-01 0.24600 -0.036500 -0.243000 8.27e-01 1.44e-01
REACTOME BIOSYNTHESIS OF MARESINS 7 3.41e-01 5.79e-01 0.35800 0.238000 0.268000 2.75e-01 2.20e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING 88 3.43e-01 5.80e-01 0.10100 -0.073500 -0.069600 2.34e-01 2.59e-01
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15 6 3.43e-01 5.80e-01 0.37900 0.194000 0.326000 4.11e-01 1.67e-01
REACTOME CGMP EFFECTS 16 3.44e-01 5.81e-01 0.23000 0.204000 0.106000 1.59e-01 4.61e-01
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS 10 3.44e-01 5.81e-01 0.28600 -0.262000 -0.116000 1.52e-01 5.24e-01
REACTOME TIGHT JUNCTION INTERACTIONS 29 3.46e-01 5.83e-01 0.13500 -0.081700 0.108000 4.46e-01 3.15e-01
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS 29 3.47e-01 5.84e-01 0.14500 -0.143000 0.023700 1.83e-01 8.25e-01
REACTOME FRUCTOSE CATABOLISM 5 3.47e-01 5.84e-01 0.42100 0.297000 0.299000 2.51e-01 2.47e-01
REACTOME NETRIN 1 SIGNALING 49 3.50e-01 5.87e-01 0.10800 -0.030300 0.104000 7.14e-01 2.07e-01
REACTOME INTERLEUKIN 23 SIGNALING 9 3.50e-01 5.87e-01 0.31000 0.179000 0.253000 3.52e-01 1.89e-01
REACTOME BILE ACID AND BILE SALT METABOLISM 45 3.50e-01 5.87e-01 0.12500 0.015300 0.124000 8.59e-01 1.51e-01
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE 6 3.51e-01 5.88e-01 0.34500 -0.059300 -0.340000 8.01e-01 1.49e-01
REACTOME EGFR TRANSACTIVATION BY GASTRIN 9 3.53e-01 5.90e-01 0.29300 0.096600 0.277000 6.16e-01 1.51e-01
REACTOME NEUREXINS AND NEUROLIGINS 51 3.53e-01 5.91e-01 0.10100 -0.071700 0.070700 3.76e-01 3.83e-01
REACTOME RHOD GTPASE CYCLE 49 3.54e-01 5.91e-01 0.11500 -0.115000 -0.000154 1.63e-01 9.99e-01
REACTOME SIGNALING BY RNF43 MUTANTS 8 3.54e-01 5.91e-01 0.25800 0.124000 -0.226000 5.45e-01 2.68e-01
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE 15 3.55e-01 5.91e-01 0.24100 -0.175000 -0.165000 2.41e-01 2.67e-01
REACTOME INTERFERON ALPHA BETA SIGNALING 64 3.55e-01 5.92e-01 0.09160 0.040400 -0.082200 5.76e-01 2.55e-01
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT 15 3.57e-01 5.93e-01 0.18800 -0.091500 0.164000 5.40e-01 2.72e-01
REACTOME RHO GTPASES ACTIVATE PAKS 19 3.57e-01 5.93e-01 0.21300 0.152000 0.150000 2.52e-01 2.58e-01
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT 5 3.57e-01 5.93e-01 0.41000 0.342000 0.226000 1.85e-01 3.81e-01
REACTOME ACYL CHAIN REMODELLING OF PE 29 3.61e-01 5.98e-01 0.13300 -0.105000 0.081100 3.29e-01 4.50e-01
REACTOME SIGNALING BY PDGFR IN DISEASE 20 3.62e-01 5.98e-01 0.20600 -0.156000 -0.135000 2.29e-01 2.95e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS 14 3.63e-01 5.98e-01 0.21000 -0.210000 0.009160 1.74e-01 9.53e-01
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS 38 3.63e-01 5.98e-01 0.14800 0.082100 0.123000 3.81e-01 1.90e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION 16 3.63e-01 5.98e-01 0.21200 0.050800 0.205000 7.25e-01 1.55e-01
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 24 3.63e-01 5.98e-01 0.17300 0.168000 0.043700 1.55e-01 7.11e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5 6 3.63e-01 5.98e-01 0.31800 0.023200 -0.317000 9.22e-01 1.78e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS 29 3.64e-01 5.98e-01 0.14500 -0.009990 0.145000 9.26e-01 1.78e-01
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA 17 3.64e-01 5.98e-01 0.21600 -0.193000 -0.097700 1.69e-01 4.85e-01
REACTOME CIRCADIAN CLOCK 69 3.64e-01 5.98e-01 0.11000 -0.087000 -0.067900 2.11e-01 3.29e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 16 3.65e-01 5.99e-01 0.21900 -0.202000 -0.085900 1.62e-01 5.52e-01
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 26 3.65e-01 5.99e-01 0.17700 -0.091600 -0.151000 4.19e-01 1.82e-01
REACTOME REGULATION OF NF KAPPA B SIGNALING 17 3.66e-01 5.99e-01 0.17600 -0.162000 0.070200 2.48e-01 6.16e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES 35 3.68e-01 6.01e-01 0.13800 -0.017300 -0.137000 8.59e-01 1.61e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING 29 3.68e-01 6.01e-01 0.16000 -0.151000 -0.051800 1.59e-01 6.29e-01
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 16 3.68e-01 6.01e-01 0.19400 -0.193000 0.014200 1.81e-01 9.21e-01
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING 32 3.68e-01 6.01e-01 0.13300 0.025600 -0.131000 8.02e-01 2.01e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING 5 3.69e-01 6.01e-01 0.31500 -0.211000 0.234000 4.15e-01 3.65e-01
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY 6 3.69e-01 6.01e-01 0.30200 -0.290000 0.084200 2.19e-01 7.21e-01
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY 14 3.72e-01 6.05e-01 0.23600 -0.210000 -0.109000 1.74e-01 4.81e-01
REACTOME PERK REGULATES GENE EXPRESSION 30 3.72e-01 6.05e-01 0.15700 -0.055000 -0.147000 6.02e-01 1.63e-01
REACTOME MET ACTIVATES PI3K AKT SIGNALING 6 3.73e-01 6.05e-01 0.28600 0.211000 -0.193000 3.71e-01 4.14e-01
REACTOME SYNTHESIS OF PI 5 3.74e-01 6.07e-01 0.31200 -0.233000 0.209000 3.68e-01 4.19e-01
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET 7 3.75e-01 6.07e-01 0.26900 0.122000 -0.240000 5.77e-01 2.72e-01
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES 7 3.75e-01 6.07e-01 0.28500 0.041200 -0.282000 8.50e-01 1.96e-01
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE 16 3.76e-01 6.08e-01 0.22000 -0.194000 -0.104000 1.79e-01 4.73e-01
REACTOME AUTOPHAGY 144 3.76e-01 6.08e-01 0.07450 -0.062600 -0.040400 1.95e-01 4.02e-01
REACTOME PROPIONYL COA CATABOLISM 5 3.77e-01 6.09e-01 0.33400 0.058200 -0.329000 8.22e-01 2.03e-01
REACTOME DEFECTIVE CHSY1 CAUSES TPBS 7 3.78e-01 6.09e-01 0.26600 -0.228000 0.137000 2.97e-01 5.30e-01
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS 20 3.78e-01 6.09e-01 0.15600 -0.095100 0.123000 4.62e-01 3.39e-01
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR 21 3.78e-01 6.09e-01 0.19500 -0.109000 -0.161000 3.86e-01 2.01e-01
REACTOME SIGNALING BY EGFR IN CANCER 24 3.81e-01 6.12e-01 0.14100 -0.094600 0.105000 4.22e-01 3.73e-01
REACTOME PLASMA LIPOPROTEIN REMODELING 31 3.82e-01 6.14e-01 0.13800 -0.006210 0.137000 9.52e-01 1.86e-01
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION 12 3.83e-01 6.14e-01 0.22800 -0.227000 -0.016600 1.73e-01 9.20e-01
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS 11 3.84e-01 6.14e-01 0.23700 -0.236000 -0.015300 1.75e-01 9.30e-01
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION 6 3.84e-01 6.14e-01 0.36400 -0.287000 -0.223000 2.23e-01 3.44e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 26 3.84e-01 6.14e-01 0.16500 -0.054800 -0.156000 6.29e-01 1.69e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI 18 3.84e-01 6.14e-01 0.16400 -0.089300 0.137000 5.12e-01 3.13e-01
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES 11 3.85e-01 6.14e-01 0.26900 -0.172000 -0.207000 3.23e-01 2.35e-01
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING 45 3.86e-01 6.15e-01 0.11200 0.111000 -0.011700 1.96e-01 8.92e-01
REACTOME CD28 CO STIMULATION 32 3.86e-01 6.15e-01 0.14900 0.140000 0.050400 1.70e-01 6.22e-01
REACTOME RHOBTB2 GTPASE CYCLE 21 3.87e-01 6.15e-01 0.19200 -0.161000 -0.105000 2.02e-01 4.05e-01
REACTOME INTERLEUKIN 1 PROCESSING 9 3.87e-01 6.15e-01 0.29000 0.139000 0.254000 4.69e-01 1.87e-01
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS 12 3.87e-01 6.15e-01 0.19900 -0.159000 0.120000 3.40e-01 4.74e-01
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE 8 3.87e-01 6.15e-01 0.28800 0.281000 0.062600 1.69e-01 7.59e-01
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS 27 3.88e-01 6.15e-01 0.17100 0.116000 0.126000 2.95e-01 2.57e-01
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION 11 3.89e-01 6.16e-01 0.22900 -0.228000 0.011100 1.90e-01 9.49e-01
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE 20 3.89e-01 6.16e-01 0.19800 -0.154000 -0.125000 2.34e-01 3.33e-01
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM 6 3.90e-01 6.16e-01 0.28300 -0.141000 0.245000 5.50e-01 2.99e-01
REACTOME PHOSPHORYLATION OF EMI1 6 3.90e-01 6.16e-01 0.35100 -0.312000 -0.161000 1.85e-01 4.94e-01
REACTOME GPVI MEDIATED ACTIVATION CASCADE 35 3.90e-01 6.16e-01 0.15000 0.099900 0.112000 3.06e-01 2.52e-01
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING 14 3.91e-01 6.17e-01 0.18500 -0.094800 0.158000 5.39e-01 3.05e-01
REACTOME CA DEPENDENT EVENTS 36 3.94e-01 6.20e-01 0.11400 -0.093900 0.064900 3.30e-01 5.00e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 28 3.94e-01 6.20e-01 0.16700 -0.115000 -0.121000 2.90e-01 2.69e-01
REACTOME LYSINE CATABOLISM 12 3.94e-01 6.20e-01 0.23400 -0.227000 -0.054900 1.73e-01 7.42e-01
REACTOME NEUROTRANSMITTER RELEASE CYCLE 48 3.96e-01 6.22e-01 0.11600 -0.114000 -0.025600 1.74e-01 7.59e-01
REACTOME MYOCLONIC EPILEPSY OF LAFORA 9 3.97e-01 6.23e-01 0.23100 -0.097400 0.210000 6.13e-01 2.76e-01
REACTOME GABA B RECEPTOR ACTIVATION 42 3.97e-01 6.23e-01 0.10800 -0.098600 0.042900 2.69e-01 6.30e-01
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 12 3.98e-01 6.23e-01 0.20200 0.074400 -0.188000 6.55e-01 2.61e-01
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS 87 3.98e-01 6.23e-01 0.07480 -0.069000 0.028900 2.66e-01 6.41e-01
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE 21 3.99e-01 6.25e-01 0.17400 -0.170000 -0.033100 1.76e-01 7.93e-01
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX 8 4.00e-01 6.25e-01 0.30500 -0.163000 -0.257000 4.24e-01 2.07e-01
REACTOME SYNAPTIC ADHESION LIKE MOLECULES 19 4.02e-01 6.26e-01 0.15400 -0.116000 0.102000 3.81e-01 4.42e-01
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION 13 4.02e-01 6.26e-01 0.23100 0.214000 0.085800 1.82e-01 5.92e-01
REACTOME SHC MEDIATED CASCADE FGFR1 21 4.02e-01 6.26e-01 0.17300 -0.170000 -0.031400 1.78e-01 8.03e-01
REACTOME DEFECTIVE LFNG CAUSES SCDO3 5 4.03e-01 6.27e-01 0.30100 -0.184000 0.239000 4.76e-01 3.56e-01
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS 7 4.04e-01 6.29e-01 0.27300 -0.270000 0.042100 2.16e-01 8.47e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN 21 4.05e-01 6.29e-01 0.18900 -0.152000 -0.112000 2.29e-01 3.73e-01
REACTOME MUCOPOLYSACCHARIDOSES 10 4.06e-01 6.29e-01 0.22000 -0.073600 0.207000 6.87e-01 2.57e-01
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION 19 4.06e-01 6.29e-01 0.17200 -0.172000 -0.001610 1.94e-01 9.90e-01
REACTOME RAC2 GTPASE CYCLE 82 4.07e-01 6.29e-01 0.07490 -0.037600 0.064800 5.57e-01 3.11e-01
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING 102 4.07e-01 6.29e-01 0.08440 0.072700 0.042900 2.05e-01 4.54e-01
REACTOME MHC CLASS II ANTIGEN PRESENTATION 121 4.07e-01 6.29e-01 0.07450 0.024800 0.070200 6.38e-01 1.82e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE 72 4.07e-01 6.29e-01 0.07930 -0.045300 0.065000 5.06e-01 3.40e-01
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA 5 4.09e-01 6.31e-01 0.31000 -0.291000 0.104000 2.59e-01 6.87e-01
REACTOME INTERLEUKIN 2 SIGNALING 10 4.09e-01 6.31e-01 0.27400 0.195000 0.192000 2.86e-01 2.92e-01
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS 5 4.11e-01 6.32e-01 0.38500 0.245000 0.297000 3.42e-01 2.51e-01
REACTOME INTERLEUKIN 27 SIGNALING 11 4.11e-01 6.32e-01 0.25400 -0.125000 -0.221000 4.73e-01 2.04e-01
REACTOME PROLONGED ERK ACTIVATION EVENTS 14 4.11e-01 6.32e-01 0.18700 -0.180000 0.050600 2.44e-01 7.43e-01
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN 6 4.12e-01 6.33e-01 0.27100 -0.205000 0.177000 3.85e-01 4.52e-01
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS 99 4.13e-01 6.33e-01 0.08670 -0.063300 -0.059300 2.77e-01 3.08e-01
REACTOME NONHOMOLOGOUS END JOINING NHEJ 64 4.14e-01 6.35e-01 0.10300 -0.039900 -0.094600 5.81e-01 1.91e-01
REACTOME PYRIMIDINE SALVAGE 10 4.15e-01 6.36e-01 0.25000 0.242000 0.062200 1.85e-01 7.34e-01
REACTOME PHYSIOLOGICAL FACTORS 14 4.16e-01 6.36e-01 0.18100 0.072800 -0.166000 6.37e-01 2.82e-01
REACTOME ACYL CHAIN REMODELLING OF PS 22 4.17e-01 6.38e-01 0.14400 -0.057500 0.133000 6.41e-01 2.82e-01
REACTOME RIPK1 MEDIATED REGULATED NECROSIS 30 4.18e-01 6.38e-01 0.12100 -0.069300 0.099100 5.11e-01 3.47e-01
REACTOME VITAMIN D CALCIFEROL METABOLISM 12 4.18e-01 6.38e-01 0.20100 -0.196000 0.047100 2.40e-01 7.77e-01
REACTOME CD209 DC SIGN SIGNALING 20 4.18e-01 6.38e-01 0.17200 0.029700 0.170000 8.18e-01 1.88e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 24 4.19e-01 6.38e-01 0.17400 -0.114000 -0.131000 3.33e-01 2.65e-01
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE 7 4.20e-01 6.38e-01 0.31900 -0.261000 -0.183000 2.31e-01 4.02e-01
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION 28 4.20e-01 6.38e-01 0.14400 -0.142000 -0.017300 1.92e-01 8.74e-01
REACTOME PASSIVE TRANSPORT BY AQUAPORINS 13 4.20e-01 6.38e-01 0.23500 0.144000 0.186000 3.69e-01 2.46e-01
REACTOME NEGATIVE REGULATION OF FLT3 15 4.20e-01 6.38e-01 0.17000 -0.138000 0.099800 3.55e-01 5.04e-01
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION 41 4.22e-01 6.39e-01 0.11600 -0.116000 -0.004660 2.00e-01 9.59e-01
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 58 4.23e-01 6.40e-01 0.10800 -0.046100 -0.097200 5.44e-01 2.00e-01
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY 25 4.23e-01 6.41e-01 0.16900 -0.105000 -0.132000 3.63e-01 2.52e-01
REACTOME INTERLEUKIN 12 FAMILY SIGNALING 55 4.24e-01 6.41e-01 0.09650 0.008740 -0.096100 9.11e-01 2.18e-01
REACTOME SIGNALING BY INTERLEUKINS 449 4.25e-01 6.42e-01 0.03200 0.012900 -0.029300 6.41e-01 2.88e-01
REACTOME PI METABOLISM 78 4.26e-01 6.43e-01 0.07460 -0.039400 0.063300 5.47e-01 3.34e-01
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 44 4.26e-01 6.43e-01 0.12700 -0.083800 -0.096000 3.36e-01 2.71e-01
REACTOME PI3K AKT SIGNALING IN CANCER 100 4.31e-01 6.50e-01 0.06570 -0.057400 0.032100 3.22e-01 5.80e-01
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE 20 4.33e-01 6.50e-01 0.14500 -0.113000 0.090700 3.84e-01 4.83e-01
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION 37 4.33e-01 6.50e-01 0.11500 0.014000 -0.114000 8.83e-01 2.28e-01
REACTOME SEMAPHORIN INTERACTIONS 61 4.33e-01 6.50e-01 0.10700 0.064800 0.084900 3.82e-01 2.52e-01
REACTOME PI3K EVENTS IN ERBB4 SIGNALING 10 4.33e-01 6.50e-01 0.20500 -0.165000 0.121000 3.65e-01 5.09e-01
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS 8 4.33e-01 6.50e-01 0.29300 0.165000 0.242000 4.19e-01 2.37e-01
REACTOME SIGNALING BY ERBB2 IN CANCER 26 4.34e-01 6.50e-01 0.12900 -0.114000 0.059200 3.13e-01 6.01e-01
REACTOME MET ACTIVATES PTK2 SIGNALING 29 4.35e-01 6.51e-01 0.15200 0.076900 0.131000 4.73e-01 2.22e-01
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS 10 4.36e-01 6.51e-01 0.23900 -0.235000 -0.042900 1.99e-01 8.14e-01
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY 24 4.36e-01 6.51e-01 0.16200 0.059100 0.150000 6.16e-01 2.02e-01
REACTOME RHOQ GTPASE CYCLE 57 4.37e-01 6.52e-01 0.08670 -0.077300 0.039200 3.13e-01 6.09e-01
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION 14 4.37e-01 6.52e-01 0.21300 -0.195000 -0.086500 2.06e-01 5.75e-01
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION 27 4.38e-01 6.52e-01 0.14800 -0.036900 -0.143000 7.40e-01 1.99e-01
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS 5 4.39e-01 6.53e-01 0.37100 0.280000 0.243000 2.78e-01 3.47e-01
REACTOME SIGNALING BY VEGF 103 4.40e-01 6.54e-01 0.06570 -0.062200 0.021100 2.75e-01 7.11e-01
REACTOME UREA CYCLE 9 4.41e-01 6.55e-01 0.25600 0.246000 0.071000 2.01e-01 7.12e-01
REACTOME POLO LIKE KINASE MEDIATED EVENTS 16 4.41e-01 6.55e-01 0.20300 -0.105000 -0.174000 4.68e-01 2.28e-01
REACTOME L1CAM INTERACTIONS 112 4.42e-01 6.55e-01 0.06740 -0.000742 0.067400 9.89e-01 2.18e-01
REACTOME MET ACTIVATES RAP1 AND RAC1 11 4.43e-01 6.56e-01 0.19200 0.137000 -0.134000 4.30e-01 4.42e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM 31 4.43e-01 6.56e-01 0.12900 -0.129000 -0.002900 2.15e-01 9.78e-01
REACTOME THE NLRP3 INFLAMMASOME 16 4.43e-01 6.56e-01 0.18600 -0.183000 -0.029700 2.04e-01 8.37e-01
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS 5 4.44e-01 6.56e-01 0.31800 -0.000884 0.318000 9.97e-01 2.18e-01
REACTOME HSF1 DEPENDENT TRANSACTIVATION 37 4.44e-01 6.56e-01 0.10900 -0.033600 0.104000 7.23e-01 2.75e-01
REACTOME UBIQUINOL BIOSYNTHESIS 8 4.45e-01 6.56e-01 0.27000 -0.074400 -0.260000 7.15e-01 2.04e-01
REACTOME MET PROMOTES CELL MOTILITY 40 4.47e-01 6.56e-01 0.13000 0.096800 0.086600 2.89e-01 3.43e-01
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE 7 4.47e-01 6.56e-01 0.28900 -0.277000 -0.083300 2.05e-01 7.03e-01
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION 31 4.47e-01 6.56e-01 0.13900 -0.131000 -0.046200 2.07e-01 6.56e-01
REACTOME HS GAG BIOSYNTHESIS 28 4.47e-01 6.56e-01 0.15100 -0.072100 -0.133000 5.09e-01 2.24e-01
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES 15 4.48e-01 6.56e-01 0.17600 -0.028800 0.173000 8.47e-01 2.45e-01
REACTOME MITOPHAGY 28 4.48e-01 6.56e-01 0.15500 -0.105000 -0.115000 3.38e-01 2.94e-01
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK 109 4.48e-01 6.56e-01 0.06340 -0.060500 0.019100 2.76e-01 7.31e-01
REACTOME PI 3K CASCADE FGFR4 19 4.48e-01 6.56e-01 0.16800 -0.022900 -0.167000 8.63e-01 2.09e-01
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2 12 4.48e-01 6.56e-01 0.20200 -0.201000 0.009480 2.27e-01 9.55e-01
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION 29 4.51e-01 6.60e-01 0.14800 -0.130000 -0.069700 2.25e-01 5.16e-01
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING 23 4.52e-01 6.60e-01 0.14800 0.148000 0.006290 2.18e-01 9.58e-01
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS 19 4.52e-01 6.60e-01 0.14500 -0.116000 0.086200 3.81e-01 5.15e-01
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS 16 4.53e-01 6.60e-01 0.19000 -0.181000 -0.057800 2.09e-01 6.89e-01
REACTOME NGF INDEPENDANT TRKA ACTIVATION 5 4.53e-01 6.60e-01 0.32800 -0.324000 -0.052900 2.10e-01 8.38e-01
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION 14 4.53e-01 6.60e-01 0.20700 0.079500 0.192000 6.06e-01 2.14e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 16 4.55e-01 6.62e-01 0.20000 -0.109000 -0.168000 4.49e-01 2.46e-01
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA 17 4.56e-01 6.63e-01 0.19600 -0.124000 -0.152000 3.77e-01 2.78e-01
REACTOME RAP1 SIGNALLING 16 4.58e-01 6.65e-01 0.16100 -0.150000 0.059100 3.00e-01 6.82e-01
REACTOME SIGNALING BY ALK IN CANCER 53 4.59e-01 6.65e-01 0.10900 -0.057400 -0.092900 4.70e-01 2.42e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS 25 4.60e-01 6.67e-01 0.12800 -0.119000 0.047000 3.01e-01 6.84e-01
REACTOME RUNX3 REGULATES NOTCH SIGNALING 13 4.61e-01 6.67e-01 0.20100 0.198000 0.030800 2.16e-01 8.48e-01
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION 5 4.61e-01 6.67e-01 0.35400 -0.300000 -0.189000 2.46e-01 4.63e-01
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS 12 4.65e-01 6.71e-01 0.19800 -0.006410 0.198000 9.69e-01 2.36e-01
REACTOME PI5P REGULATES TP53 ACETYLATION 9 4.65e-01 6.71e-01 0.26600 -0.172000 -0.204000 3.72e-01 2.90e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING 24 4.65e-01 6.71e-01 0.12600 -0.097100 0.080400 4.10e-01 4.96e-01
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION 155 4.66e-01 6.72e-01 0.06180 -0.025000 -0.056500 5.91e-01 2.25e-01
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION 6 4.68e-01 6.73e-01 0.25500 -0.121000 0.224000 6.07e-01 3.42e-01
REACTOME NONCANONICAL ACTIVATION OF NOTCH3 8 4.68e-01 6.73e-01 0.26600 -0.089000 -0.250000 6.63e-01 2.20e-01
REACTOME CA2 PATHWAY 62 4.68e-01 6.74e-01 0.09710 -0.039000 -0.088900 5.96e-01 2.26e-01
REACTOME SIGNALING BY MET 77 4.69e-01 6.74e-01 0.07040 -0.039600 0.058200 5.48e-01 3.77e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION 29 4.71e-01 6.76e-01 0.11900 -0.113000 0.036600 2.93e-01 7.33e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS 11 4.72e-01 6.77e-01 0.22200 -0.213000 -0.064100 2.21e-01 7.13e-01
REACTOME SIGNALING BY RETINOIC ACID 40 4.73e-01 6.77e-01 0.11300 -0.112000 -0.020200 2.22e-01 8.25e-01
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS 22 4.73e-01 6.77e-01 0.16300 -0.147000 -0.068900 2.32e-01 5.76e-01
REACTOME DAG AND IP3 SIGNALING 40 4.74e-01 6.78e-01 0.09690 -0.080200 0.054500 3.80e-01 5.51e-01
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM 13 4.75e-01 6.79e-01 0.21900 -0.150000 -0.160000 3.50e-01 3.18e-01
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR 7 4.76e-01 6.79e-01 0.27300 -0.063300 -0.266000 7.72e-01 2.23e-01
REACTOME GABA RECEPTOR ACTIVATION 56 4.77e-01 6.79e-01 0.08510 -0.024400 0.081600 7.52e-01 2.91e-01
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES 6 4.77e-01 6.79e-01 0.30600 0.284000 0.114000 2.29e-01 6.28e-01
REACTOME ESTROGEN BIOSYNTHESIS 6 4.77e-01 6.80e-01 0.26100 0.253000 -0.065100 2.83e-01 7.82e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES 15 4.79e-01 6.81e-01 0.18900 -0.053900 -0.181000 7.18e-01 2.25e-01
REACTOME VASOPRESSIN LIKE RECEPTORS 5 4.80e-01 6.82e-01 0.27100 -0.167000 0.213000 5.17e-01 4.10e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS 21 4.80e-01 6.82e-01 0.17000 0.100000 0.137000 4.27e-01 2.77e-01
REACTOME EPH EPHRIN SIGNALING 90 4.82e-01 6.83e-01 0.08220 -0.065400 -0.049800 2.84e-01 4.15e-01
REACTOME MET INTERACTS WITH TNS PROTEINS 5 4.82e-01 6.83e-01 0.33900 0.302000 0.154000 2.42e-01 5.52e-01
REACTOME UNWINDING OF DNA 12 4.82e-01 6.83e-01 0.17500 0.094900 -0.147000 5.69e-01 3.77e-01
REACTOME ARMS MEDIATED ACTIVATION 7 4.82e-01 6.83e-01 0.24300 -0.239000 0.045900 2.73e-01 8.34e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS 35 4.84e-01 6.83e-01 0.12300 -0.034300 -0.118000 7.26e-01 2.28e-01
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION 9 4.84e-01 6.83e-01 0.24100 -0.066200 -0.232000 7.31e-01 2.28e-01
REACTOME REGULATION OF IFNG SIGNALING 14 4.85e-01 6.85e-01 0.20800 -0.138000 -0.155000 3.70e-01 3.15e-01
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION 5 4.86e-01 6.86e-01 0.33500 -0.302000 -0.144000 2.42e-01 5.77e-01
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED 6 4.87e-01 6.86e-01 0.31700 -0.210000 -0.237000 3.73e-01 3.14e-01
REACTOME CHOLINE CATABOLISM 6 4.87e-01 6.86e-01 0.25500 0.079300 -0.242000 7.37e-01 3.05e-01
REACTOME RORA ACTIVATES GENE EXPRESSION 17 4.91e-01 6.90e-01 0.15000 0.143000 -0.047100 3.08e-01 7.37e-01
REACTOME TYROSINE CATABOLISM 5 4.91e-01 6.90e-01 0.33900 0.177000 0.289000 4.94e-01 2.63e-01
REACTOME DISEASES OF CARBOHYDRATE METABOLISM 30 4.92e-01 6.90e-01 0.11300 -0.037700 0.106000 7.21e-01 3.14e-01
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS 89 4.92e-01 6.90e-01 0.08190 0.058200 0.057600 3.43e-01 3.48e-01
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION 19 4.92e-01 6.90e-01 0.13700 -0.114000 0.076800 3.92e-01 5.62e-01
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR 11 4.93e-01 6.91e-01 0.19500 -0.021700 0.194000 9.01e-01 2.66e-01
REACTOME TELOMERE EXTENSION BY TELOMERASE 22 4.94e-01 6.91e-01 0.13700 0.016400 -0.136000 8.94e-01 2.68e-01
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING 5 4.95e-01 6.92e-01 0.27400 -0.257000 0.094800 3.19e-01 7.14e-01
REACTOME CHL1 INTERACTIONS 9 4.96e-01 6.94e-01 0.25100 0.213000 0.134000 2.70e-01 4.87e-01
REACTOME AGGREPHAGY 42 4.97e-01 6.94e-01 0.09300 -0.040800 0.083500 6.47e-01 3.49e-01
REACTOME SCAVENGING BY CLASS B RECEPTORS 6 4.97e-01 6.94e-01 0.29500 0.102000 0.277000 6.65e-01 2.40e-01
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION 5 4.98e-01 6.94e-01 0.31200 -0.068200 -0.305000 7.92e-01 2.38e-01
REACTOME CHYLOMICRON CLEARANCE 5 5.02e-01 6.99e-01 0.33800 0.207000 0.268000 4.23e-01 3.00e-01
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING 72 5.04e-01 7.01e-01 0.08590 -0.078100 -0.035700 2.52e-01 6.01e-01
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM 11 5.04e-01 7.01e-01 0.22700 -0.141000 -0.178000 4.18e-01 3.06e-01
REACTOME RND3 GTPASE CYCLE 41 5.06e-01 7.03e-01 0.11300 -0.046100 -0.103000 6.09e-01 2.52e-01
REACTOME METHYLATION 14 5.08e-01 7.05e-01 0.19100 -0.178000 -0.068500 2.49e-01 6.57e-01
REACTOME PYRIMIDINE CATABOLISM 12 5.09e-01 7.05e-01 0.17600 0.047700 -0.169000 7.75e-01 3.10e-01
REACTOME FLT3 SIGNALING 38 5.10e-01 7.07e-01 0.09680 -0.036400 0.089700 6.98e-01 3.39e-01
REACTOME ANDROGEN BIOSYNTHESIS 11 5.12e-01 7.07e-01 0.22300 0.123000 0.186000 4.79e-01 2.86e-01
REACTOME PHENYLALANINE METABOLISM 6 5.12e-01 7.07e-01 0.30000 0.256000 0.157000 2.78e-01 5.04e-01
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES 58 5.12e-01 7.07e-01 0.07570 -0.052700 0.054300 4.87e-01 4.74e-01
REACTOME GLUCONEOGENESIS 33 5.12e-01 7.07e-01 0.10700 0.023500 -0.104000 8.15e-01 3.01e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES 12 5.14e-01 7.09e-01 0.19000 0.014300 0.189000 9.31e-01 2.56e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS 35 5.14e-01 7.09e-01 0.10500 -0.104000 0.015400 2.87e-01 8.74e-01
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS 17 5.15e-01 7.10e-01 0.15200 0.151000 -0.016600 2.82e-01 9.06e-01
REACTOME PYROPTOSIS 27 5.17e-01 7.11e-01 0.12200 -0.006600 0.122000 9.53e-01 2.74e-01
REACTOME CARGO CONCENTRATION IN THE ER 32 5.17e-01 7.11e-01 0.12600 -0.115000 -0.053200 2.62e-01 6.03e-01
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION 26 5.18e-01 7.12e-01 0.13600 0.042300 0.130000 7.09e-01 2.53e-01
REACTOME PHOSPHORYLATION OF THE APC C 20 5.20e-01 7.14e-01 0.12800 -0.105000 0.074000 4.18e-01 5.67e-01
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS 54 5.21e-01 7.15e-01 0.10000 0.079000 0.061500 3.15e-01 4.35e-01
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 33 5.23e-01 7.16e-01 0.12700 -0.106000 -0.068300 2.90e-01 4.97e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS 12 5.23e-01 7.16e-01 0.17600 -0.173000 0.030800 2.99e-01 8.53e-01
REACTOME LAGGING STRAND SYNTHESIS 19 5.25e-01 7.18e-01 0.14700 -0.008040 -0.147000 9.52e-01 2.67e-01
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS 9 5.27e-01 7.20e-01 0.19600 -0.060900 0.186000 7.52e-01 3.33e-01
REACTOME PI 3K CASCADE FGFR2 21 5.28e-01 7.20e-01 0.16000 -0.107000 -0.119000 3.97e-01 3.47e-01
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS 5 5.28e-01 7.20e-01 0.26200 0.085800 -0.248000 7.40e-01 3.38e-01
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS 7 5.28e-01 7.20e-01 0.24800 -0.245000 -0.038900 2.61e-01 8.59e-01
REACTOME DISEASES OF IMMUNE SYSTEM 29 5.29e-01 7.21e-01 0.10500 -0.081900 0.065100 4.45e-01 5.44e-01
REACTOME DNA DOUBLE STRAND BREAK RESPONSE 74 5.30e-01 7.21e-01 0.08360 -0.070800 -0.044400 2.92e-01 5.09e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION 15 5.32e-01 7.24e-01 0.14500 0.110000 -0.093600 4.60e-01 5.30e-01
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY 8 5.34e-01 7.26e-01 0.20500 0.067000 -0.194000 7.43e-01 3.42e-01
REACTOME METABOLISM OF PORPHYRINS 26 5.34e-01 7.26e-01 0.13200 -0.127000 -0.035900 2.63e-01 7.51e-01
REACTOME RND2 GTPASE CYCLE 42 5.35e-01 7.26e-01 0.10100 -0.016900 -0.099300 8.50e-01 2.65e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER 8 5.35e-01 7.26e-01 0.25000 -0.124000 -0.217000 5.44e-01 2.88e-01
REACTOME SHC1 EVENTS IN EGFR SIGNALING 13 5.36e-01 7.26e-01 0.19800 0.108000 0.166000 5.00e-01 3.01e-01
REACTOME TRANSPORT OF RCBL WITHIN THE BODY 8 5.37e-01 7.26e-01 0.20500 -0.066500 0.194000 7.45e-01 3.43e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG 7 5.37e-01 7.26e-01 0.22300 -0.218000 0.047900 3.17e-01 8.26e-01
REACTOME PHASE 0 RAPID DEPOLARISATION 31 5.37e-01 7.26e-01 0.12400 -0.113000 -0.050700 2.74e-01 6.25e-01
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY 5 5.41e-01 7.31e-01 0.31600 -0.265000 -0.173000 3.05e-01 5.04e-01
REACTOME SIGNALING BY BMP 27 5.44e-01 7.34e-01 0.13200 -0.120000 -0.054600 2.80e-01 6.23e-01
REACTOME TRIGLYCERIDE BIOSYNTHESIS 12 5.44e-01 7.34e-01 0.16800 -0.164000 0.038100 3.25e-01 8.19e-01
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING 5 5.46e-01 7.35e-01 0.26700 -0.030000 0.265000 9.07e-01 3.04e-01
REACTOME INOSITOL PHOSPHATE METABOLISM 44 5.47e-01 7.36e-01 0.08450 -0.076200 0.036500 3.82e-01 6.76e-01
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION 49 5.48e-01 7.37e-01 0.09260 0.019600 0.090500 8.12e-01 2.73e-01
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR 106 5.49e-01 7.38e-01 0.06020 -0.002890 -0.060200 9.59e-01 2.85e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS 31 5.51e-01 7.40e-01 0.12100 -0.045100 -0.112000 6.64e-01 2.81e-01
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION 5 5.52e-01 7.41e-01 0.29000 -0.071400 -0.282000 7.82e-01 2.76e-01
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS 46 5.53e-01 7.41e-01 0.10200 0.051700 0.087700 5.44e-01 3.03e-01
REACTOME VLDL CLEARANCE 6 5.53e-01 7.41e-01 0.22100 0.157000 -0.156000 5.05e-01 5.09e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS 8 5.54e-01 7.42e-01 0.19600 -0.083000 0.178000 6.84e-01 3.85e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS 7 5.56e-01 7.44e-01 0.20700 -0.099700 0.182000 6.48e-01 4.05e-01
REACTOME SPERM MOTILITY AND TAXES 9 5.59e-01 7.46e-01 0.23200 0.181000 0.145000 3.48e-01 4.52e-01
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER 7 5.59e-01 7.46e-01 0.26100 -0.153000 -0.212000 4.83e-01 3.31e-01
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS 17 5.60e-01 7.46e-01 0.16900 -0.129000 -0.109000 3.57e-01 4.38e-01
REACTOME PI 3K CASCADE FGFR3 17 5.60e-01 7.46e-01 0.16800 -0.103000 -0.133000 4.63e-01 3.42e-01
REACTOME ADHERENS JUNCTIONS INTERACTIONS 33 5.60e-01 7.46e-01 0.10300 -0.006720 0.103000 9.47e-01 3.07e-01
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS 21 5.61e-01 7.46e-01 0.13000 -0.129000 0.005870 3.04e-01 9.63e-01
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 25 5.61e-01 7.46e-01 0.13900 -0.085600 -0.109000 4.59e-01 3.46e-01
REACTOME LIPOPHAGY 9 5.66e-01 7.51e-01 0.17900 -0.152000 0.094700 4.30e-01 6.23e-01
REACTOME ACTIVATION OF TRKA RECEPTORS 6 5.66e-01 7.51e-01 0.26400 -0.250000 -0.084300 2.88e-01 7.21e-01
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES 21 5.67e-01 7.51e-01 0.13800 -0.134000 -0.032400 2.87e-01 7.97e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST 18 5.67e-01 7.51e-01 0.16300 -0.118000 -0.112000 3.87e-01 4.11e-01
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D 6 5.67e-01 7.51e-01 0.24200 -0.003540 0.242000 9.88e-01 3.05e-01
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA 6 5.68e-01 7.51e-01 0.28100 -0.215000 -0.180000 3.61e-01 4.46e-01
REACTOME INTEGRIN SIGNALING 27 5.68e-01 7.51e-01 0.11600 0.005100 0.115000 9.63e-01 2.99e-01
REACTOME CHYLOMICRON ASSEMBLY 10 5.70e-01 7.52e-01 0.18900 0.007470 0.189000 9.67e-01 3.01e-01
REACTOME ARACHIDONIC ACID METABOLISM 56 5.70e-01 7.52e-01 0.08710 0.031500 0.081200 6.84e-01 2.93e-01
REACTOME VITAMINS 6 5.70e-01 7.52e-01 0.27500 -0.234000 -0.144000 3.20e-01 5.42e-01
REACTOME IRAK4 DEFICIENCY TLR2 4 17 5.71e-01 7.52e-01 0.14700 0.014600 0.146000 9.17e-01 2.96e-01
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 5.71e-01 7.52e-01 0.17200 0.079800 0.152000 5.93e-01 3.08e-01
REACTOME PEROXISOMAL LIPID METABOLISM 28 5.72e-01 7.53e-01 0.12900 -0.079100 -0.101000 4.69e-01 3.53e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE 21 5.73e-01 7.53e-01 0.14700 -0.079800 -0.123000 5.27e-01 3.28e-01
REACTOME KETONE BODY METABOLISM 10 5.74e-01 7.53e-01 0.16600 0.107000 -0.127000 5.57e-01 4.87e-01
REACTOME SIGNALING BY EGFR 48 5.77e-01 7.57e-01 0.08210 -0.010100 0.081500 9.04e-01 3.29e-01
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA 8 5.78e-01 7.58e-01 0.20900 0.007390 0.209000 9.71e-01 3.07e-01
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION 10 5.79e-01 7.59e-01 0.19300 -0.190000 -0.031100 2.98e-01 8.65e-01
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING 38 5.80e-01 7.60e-01 0.09540 -0.003360 -0.095300 9.71e-01 3.09e-01
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE 19 5.82e-01 7.60e-01 0.15300 -0.089800 -0.124000 4.98e-01 3.49e-01
REACTOME PROSTANOID LIGAND RECEPTORS 9 5.82e-01 7.60e-01 0.22300 -0.130000 -0.181000 4.99e-01 3.48e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4 14 5.82e-01 7.60e-01 0.17800 -0.102000 -0.146000 5.10e-01 3.43e-01
REACTOME NADE MODULATES DEATH SIGNALLING 5 5.83e-01 7.61e-01 0.29000 -0.125000 -0.261000 6.27e-01 3.11e-01
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS 10 5.84e-01 7.61e-01 0.17600 -0.173000 0.030100 3.43e-01 8.69e-01
REACTOME NECTIN NECL TRANS HETERODIMERIZATION 7 5.84e-01 7.61e-01 0.19900 -0.178000 0.089600 4.15e-01 6.81e-01
REACTOME SELECTIVE AUTOPHAGY 79 5.85e-01 7.62e-01 0.06870 -0.067300 -0.013900 3.01e-01 8.31e-01
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA 14 5.85e-01 7.62e-01 0.15000 -0.149000 0.017300 3.34e-01 9.11e-01
REACTOME RAS PROCESSING 23 5.86e-01 7.62e-01 0.13100 -0.124000 -0.042000 3.03e-01 7.27e-01
REACTOME FATTY ACID METABOLISM 168 5.88e-01 7.64e-01 0.04680 -0.008750 -0.046000 8.45e-01 3.04e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS 34 5.89e-01 7.64e-01 0.11300 0.067400 0.091300 4.96e-01 3.57e-01
REACTOME RHO GTPASES ACTIVATE ROCKS 19 5.90e-01 7.65e-01 0.12000 -0.108000 0.051700 4.13e-01 6.96e-01
REACTOME P2Y RECEPTORS 8 5.92e-01 7.67e-01 0.21600 0.054600 0.209000 7.89e-01 3.06e-01
REACTOME HDL CLEARANCE 5 5.92e-01 7.67e-01 0.29600 0.210000 0.210000 4.17e-01 4.17e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING 5 5.93e-01 7.67e-01 0.28300 -0.259000 -0.114000 3.15e-01 6.58e-01
REACTOME INTERLEUKIN 21 SIGNALING 9 5.94e-01 7.68e-01 0.21500 0.108000 0.186000 5.75e-01 3.33e-01
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS 28 5.95e-01 7.68e-01 0.10400 -0.013600 0.103000 9.01e-01 3.44e-01
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC 26 5.96e-01 7.70e-01 0.10300 0.036100 -0.096500 7.50e-01 3.94e-01
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION 9 5.97e-01 7.70e-01 0.19200 0.012300 0.192000 9.49e-01 3.19e-01
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS 12 5.97e-01 7.70e-01 0.15200 -0.145000 0.047400 3.85e-01 7.76e-01
REACTOME CA2 ACTIVATED K CHANNELS 9 5.98e-01 7.70e-01 0.17200 -0.077600 0.153000 6.87e-01 4.26e-01
REACTOME SMOOTH MUSCLE CONTRACTION 43 5.99e-01 7.70e-01 0.07840 -0.036800 0.069200 6.76e-01 4.33e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM 16 5.99e-01 7.70e-01 0.13000 0.119000 -0.051500 4.09e-01 7.21e-01
REACTOME DISEASES OF GLYCOSYLATION 132 6.00e-01 7.70e-01 0.05000 -0.049900 -0.002780 3.22e-01 9.56e-01
REACTOME BICARBONATE TRANSPORTERS 10 6.01e-01 7.70e-01 0.16100 -0.135000 0.086400 4.59e-01 6.36e-01
REACTOME DERMATAN SULFATE BIOSYNTHESIS 10 6.01e-01 7.70e-01 0.20100 -0.178000 -0.093400 3.31e-01 6.09e-01
REACTOME NEF MEDIATED CD8 DOWN REGULATION 7 6.01e-01 7.70e-01 0.21800 0.217000 0.019400 3.20e-01 9.29e-01
REACTOME INTRA GOLGI TRAFFIC 42 6.02e-01 7.70e-01 0.09220 -0.020600 -0.089900 8.17e-01 3.14e-01
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS 9 6.02e-01 7.70e-01 0.21600 0.171000 0.132000 3.74e-01 4.93e-01
REACTOME PHASE 2 PLATEAU PHASE 14 6.02e-01 7.70e-01 0.14000 -0.042000 0.134000 7.86e-01 3.86e-01
REACTOME SIGNALING BY NTRK2 TRKB 25 6.07e-01 7.76e-01 0.10200 0.040100 -0.094200 7.28e-01 4.15e-01
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA 17 6.08e-01 7.76e-01 0.15600 -0.120000 -0.100000 3.93e-01 4.73e-01
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS 29 6.09e-01 7.77e-01 0.09490 -0.037400 0.087200 7.28e-01 4.16e-01
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN 45 6.10e-01 7.77e-01 0.09100 0.032400 0.085000 7.07e-01 3.24e-01
REACTOME GLUTATHIONE CONJUGATION 36 6.10e-01 7.77e-01 0.10300 0.042100 0.093900 6.62e-01 3.30e-01
REACTOME SEROTONIN RECEPTORS 11 6.11e-01 7.77e-01 0.15000 -0.125000 0.083100 4.72e-01 6.33e-01
REACTOME XENOBIOTICS 22 6.11e-01 7.77e-01 0.13200 0.058400 0.119000 6.35e-01 3.35e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION 19 6.11e-01 7.77e-01 0.12000 -0.028900 0.117000 8.27e-01 3.79e-01
REACTOME SYNTHESIS OF PA 38 6.12e-01 7.77e-01 0.08070 -0.067000 0.045000 4.75e-01 6.31e-01
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION 6 6.12e-01 7.77e-01 0.23000 -0.229000 -0.017400 3.30e-01 9.41e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN 13 6.14e-01 7.77e-01 0.14100 0.052400 -0.131000 7.43e-01 4.14e-01
REACTOME GAB1 SIGNALOSOME 16 6.14e-01 7.77e-01 0.16000 0.111000 0.115000 4.41e-01 4.26e-01
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING 25 6.14e-01 7.77e-01 0.12100 -0.113000 -0.044200 3.28e-01 7.02e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K 6 6.14e-01 7.77e-01 0.22700 0.227000 0.005910 3.37e-01 9.80e-01
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES 7 6.15e-01 7.77e-01 0.24100 -0.163000 -0.178000 4.55e-01 4.15e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 31 6.15e-01 7.77e-01 0.11300 -0.094400 -0.062200 3.63e-01 5.49e-01
REACTOME MET RECEPTOR ACTIVATION 6 6.16e-01 7.77e-01 0.22900 0.018300 0.228000 9.38e-01 3.33e-01
REACTOME HISTIDINE CATABOLISM 8 6.17e-01 7.77e-01 0.22400 0.175000 0.140000 3.92e-01 4.92e-01
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY 25 6.17e-01 7.77e-01 0.09830 -0.058200 0.079300 6.15e-01 4.93e-01
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS 11 6.18e-01 7.77e-01 0.16600 -0.166000 -0.004150 3.40e-01 9.81e-01
REACTOME ATTENUATION PHASE 27 6.18e-01 7.77e-01 0.10700 0.005350 0.107000 9.62e-01 3.38e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES 8 6.19e-01 7.77e-01 0.22400 -0.150000 -0.166000 4.62e-01 4.15e-01
REACTOME FRS MEDIATED FGFR2 SIGNALING 23 6.19e-01 7.77e-01 0.13100 -0.109000 -0.072800 3.68e-01 5.46e-01
REACTOME METABOLISM OF FOLATE AND PTERINES 17 6.19e-01 7.77e-01 0.14900 -0.069600 -0.132000 6.19e-01 3.45e-01
REACTOME HYDROLYSIS OF LPC 8 6.20e-01 7.78e-01 0.17200 -0.130000 0.113000 5.25e-01 5.80e-01
REACTOME SYNTHESIS OF GDP MANNOSE 5 6.21e-01 7.79e-01 0.28200 -0.193000 -0.206000 4.55e-01 4.24e-01
REACTOME LONG TERM POTENTIATION 22 6.22e-01 7.79e-01 0.10700 -0.039400 0.099400 7.49e-01 4.19e-01
REACTOME NRCAM INTERACTIONS 6 6.23e-01 7.79e-01 0.19900 -0.157000 0.121000 5.04e-01 6.08e-01
REACTOME SIGNALING BY LRP5 MUTANTS 6 6.23e-01 7.79e-01 0.25000 -0.221000 -0.116000 3.48e-01 6.24e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN 5 6.26e-01 7.82e-01 0.27900 -0.216000 -0.177000 4.02e-01 4.94e-01
REACTOME BASIGIN INTERACTIONS 24 6.27e-01 7.83e-01 0.10100 -0.040500 0.092500 7.31e-01 4.33e-01
REACTOME METALLOPROTEASE DUBS 36 6.28e-01 7.83e-01 0.10400 -0.074600 -0.072700 4.39e-01 4.50e-01
REACTOME MYOGENESIS 29 6.28e-01 7.83e-01 0.08920 -0.065700 0.060300 5.41e-01 5.74e-01
REACTOME ADAPTIVE IMMUNE SYSTEM 729 6.29e-01 7.83e-01 0.02300 0.011700 0.019900 5.92e-01 3.62e-01
REACTOME G PROTEIN ACTIVATION 24 6.29e-01 7.83e-01 0.11600 0.023900 0.113000 8.39e-01 3.36e-01
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA 8 6.30e-01 7.83e-01 0.17100 -0.142000 0.094500 4.86e-01 6.44e-01
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX 14 6.30e-01 7.83e-01 0.13000 -0.114000 0.062500 4.60e-01 6.85e-01
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION 8 6.31e-01 7.84e-01 0.17700 0.169000 -0.051600 4.07e-01 8.01e-01
REACTOME DEFECTS IN BIOTIN BTN METABOLISM 8 6.33e-01 7.86e-01 0.20800 0.078400 0.193000 7.01e-01 3.45e-01
REACTOME NTRK2 ACTIVATES RAC1 5 6.34e-01 7.87e-01 0.21700 0.195000 -0.095100 4.49e-01 7.13e-01
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R 9 6.35e-01 7.87e-01 0.19600 0.181000 0.074200 3.46e-01 7.00e-01
REACTOME INFLAMMASOMES 21 6.36e-01 7.87e-01 0.10300 -0.078300 0.067700 5.34e-01 5.91e-01
REACTOME INTRAFLAGELLAR TRANSPORT 50 6.36e-01 7.87e-01 0.08210 -0.027800 -0.077300 7.34e-01 3.45e-01
REACTOME INSULIN PROCESSING 24 6.37e-01 7.87e-01 0.11700 -0.112000 -0.036000 3.43e-01 7.60e-01
REACTOME RHOJ GTPASE CYCLE 51 6.38e-01 7.88e-01 0.07390 -0.073900 0.001240 3.61e-01 9.88e-01
REACTOME CTLA4 INHIBITORY SIGNALING 21 6.38e-01 7.88e-01 0.11500 0.115000 -0.000151 3.60e-01 9.99e-01
REACTOME MET ACTIVATES RAS SIGNALING 11 6.39e-01 7.88e-01 0.17900 0.160000 0.079000 3.58e-01 6.50e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS 8 6.40e-01 7.89e-01 0.19300 0.191000 0.025800 3.48e-01 9.00e-01
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION 31 6.42e-01 7.91e-01 0.09330 -0.093200 0.004080 3.69e-01 9.69e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA 27 6.44e-01 7.93e-01 0.11200 -0.047600 -0.102000 6.68e-01 3.60e-01
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION 8 6.45e-01 7.93e-01 0.17200 -0.054900 0.163000 7.88e-01 4.25e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN 7 6.49e-01 7.97e-01 0.21200 0.203000 0.061000 3.53e-01 7.80e-01
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA 5 6.49e-01 7.97e-01 0.25300 0.239000 0.081700 3.54e-01 7.52e-01
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN 35 6.50e-01 7.97e-01 0.08080 0.029700 -0.075200 7.61e-01 4.42e-01
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS 15 6.50e-01 7.97e-01 0.12200 0.111000 -0.050800 4.55e-01 7.33e-01
REACTOME GLYCOGEN STORAGE DISEASES 14 6.51e-01 7.98e-01 0.12300 -0.094400 0.079500 5.41e-01 6.07e-01
REACTOME HYALURONAN METABOLISM 16 6.53e-01 7.99e-01 0.14200 0.050400 0.132000 7.27e-01 3.60e-01
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING 22 6.54e-01 8.00e-01 0.10900 0.108000 -0.004520 3.79e-01 9.71e-01
REACTOME ALK MUTANTS BIND TKIS 12 6.54e-01 8.00e-01 0.15500 -0.153000 -0.024300 3.59e-01 8.84e-01
REACTOME HDL REMODELING 10 6.56e-01 8.01e-01 0.17500 -0.168000 -0.050900 3.59e-01 7.80e-01
REACTOME NEPHRIN FAMILY INTERACTIONS 22 6.57e-01 8.02e-01 0.12700 -0.088900 -0.090100 4.71e-01 4.64e-01
REACTOME ONCOGENIC MAPK SIGNALING 79 6.58e-01 8.03e-01 0.06670 -0.049500 -0.044700 4.47e-01 4.92e-01
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS 11 6.60e-01 8.04e-01 0.17700 -0.110000 -0.139000 5.28e-01 4.25e-01
REACTOME DNA REPLICATION INITIATION 7 6.61e-01 8.05e-01 0.21700 -0.106000 -0.190000 6.27e-01 3.85e-01
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS 18 6.63e-01 8.06e-01 0.11300 -0.110000 0.025100 4.17e-01 8.54e-01
REACTOME VITAMIN B1 THIAMIN METABOLISM 5 6.67e-01 8.11e-01 0.26000 -0.180000 -0.188000 4.87e-01 4.65e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 20 6.68e-01 8.11e-01 0.13000 -0.096900 -0.086600 4.53e-01 5.03e-01
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS 18 6.69e-01 8.11e-01 0.11400 -0.112000 0.017400 4.09e-01 8.98e-01
REACTOME DIGESTION OF DIETARY LIPID 6 6.69e-01 8.11e-01 0.23700 0.178000 0.156000 4.51e-01 5.08e-01
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION 19 6.69e-01 8.11e-01 0.10400 -0.054300 0.088100 6.82e-01 5.06e-01
REACTOME MET ACTIVATES PTPN11 5 6.70e-01 8.11e-01 0.20400 0.183000 -0.089400 4.78e-01 7.29e-01
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS 41 6.70e-01 8.11e-01 0.07710 -0.003940 0.077000 9.65e-01 3.94e-01
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY 10 6.72e-01 8.13e-01 0.18000 -0.099600 -0.150000 5.86e-01 4.11e-01
REACTOME TBC RABGAPS 41 6.74e-01 8.15e-01 0.08990 -0.061900 -0.065200 4.93e-01 4.70e-01
REACTOME FRS MEDIATED FGFR4 SIGNALING 21 6.74e-01 8.15e-01 0.11600 -0.032700 -0.112000 7.95e-01 3.75e-01
REACTOME DEFECTIVE CHST6 CAUSES MCDC1 6 6.76e-01 8.16e-01 0.22200 0.084000 0.206000 7.22e-01 3.82e-01
REACTOME ACYL CHAIN REMODELLING OF PG 18 6.77e-01 8.16e-01 0.10800 -0.103000 0.034700 4.51e-01 7.99e-01
REACTOME FRS MEDIATED FGFR3 SIGNALING 19 6.78e-01 8.17e-01 0.13000 -0.105000 -0.076000 4.27e-01 5.66e-01
REACTOME FRUCTOSE METABOLISM 7 6.78e-01 8.17e-01 0.20500 0.075500 0.190000 7.29e-01 3.83e-01
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE 29 6.79e-01 8.17e-01 0.08660 -0.084600 0.018700 4.31e-01 8.61e-01
REACTOME SODIUM CALCIUM EXCHANGERS 11 6.80e-01 8.17e-01 0.17100 0.133000 0.108000 4.46e-01 5.37e-01
REACTOME SIGNALING BY HIPPO 19 6.80e-01 8.17e-01 0.12500 -0.115000 -0.048900 3.87e-01 7.12e-01
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING 8 6.80e-01 8.17e-01 0.19300 0.078700 0.176000 7.00e-01 3.89e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING 16 6.82e-01 8.19e-01 0.11700 -0.018200 0.116000 9.00e-01 4.22e-01
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III 31 6.83e-01 8.19e-01 0.07890 -0.042000 0.066700 6.86e-01 5.20e-01
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING 44 6.84e-01 8.19e-01 0.07590 0.009310 0.075300 9.15e-01 3.88e-01
REACTOME SULFIDE OXIDATION TO SULFATE 6 6.85e-01 8.20e-01 0.22700 -0.188000 -0.127000 4.25e-01 5.90e-01
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL 7 6.86e-01 8.20e-01 0.19200 0.033900 0.189000 8.76e-01 3.87e-01
REACTOME VLDL ASSEMBLY 5 6.87e-01 8.20e-01 0.23200 0.224000 0.059800 3.86e-01 8.17e-01
REACTOME TRAIL SIGNALING 8 6.87e-01 8.20e-01 0.17300 0.006940 0.173000 9.73e-01 3.98e-01
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS 22 6.88e-01 8.20e-01 0.11500 -0.047000 -0.105000 7.03e-01 3.96e-01
REACTOME PLATELET SENSITIZATION BY LDL 17 6.88e-01 8.20e-01 0.12900 -0.047900 -0.120000 7.33e-01 3.92e-01
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS 8 6.88e-01 8.20e-01 0.18800 0.069900 0.175000 7.32e-01 3.92e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY 19 6.88e-01 8.20e-01 0.11900 0.032400 0.114000 8.07e-01 3.88e-01
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION 6 6.90e-01 8.21e-01 0.17800 -0.083000 0.158000 7.25e-01 5.03e-01
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING 22 6.95e-01 8.27e-01 0.09230 -0.082000 0.042300 5.05e-01 7.31e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION 45 6.95e-01 8.27e-01 0.08110 -0.043700 -0.068300 6.12e-01 4.28e-01
REACTOME SIGNALLING TO ERKS 34 6.96e-01 8.27e-01 0.07340 -0.061600 0.040000 5.34e-01 6.87e-01
REACTOME DOPAMINE RECEPTORS 5 6.97e-01 8.27e-01 0.19100 0.105000 -0.159000 6.84e-01 5.37e-01
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE 69 6.98e-01 8.28e-01 0.05110 0.030700 -0.040900 6.59e-01 5.57e-01
REACTOME RHOC GTPASE CYCLE 71 6.98e-01 8.28e-01 0.06490 -0.051200 -0.039900 4.56e-01 5.61e-01
REACTOME REGULATION OF IFNA IFNB SIGNALING 17 7.00e-01 8.29e-01 0.13200 -0.106000 -0.077400 4.47e-01 5.81e-01
REACTOME OVARIAN TUMOR DOMAIN PROTEASES 36 7.01e-01 8.30e-01 0.08590 -0.029800 -0.080600 7.57e-01 4.03e-01
REACTOME NEF MEDIATED CD4 DOWN REGULATION 9 7.02e-01 8.30e-01 0.18200 0.132000 0.125000 4.93e-01 5.17e-01
REACTOME CARNITINE METABOLISM 13 7.04e-01 8.32e-01 0.11900 -0.049000 0.108000 7.59e-01 5.00e-01
REACTOME TIE2 SIGNALING 18 7.05e-01 8.33e-01 0.12600 0.067200 0.106000 6.22e-01 4.36e-01
REACTOME FANCONI ANEMIA PATHWAY 37 7.05e-01 8.33e-01 0.07430 0.009750 -0.073600 9.18e-01 4.38e-01
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION 18 7.06e-01 8.33e-01 0.11200 -0.112000 -0.009930 4.11e-01 9.42e-01
REACTOME SCAVENGING BY CLASS F RECEPTORS 6 7.08e-01 8.34e-01 0.20700 -0.195000 -0.069600 4.09e-01 7.68e-01
REACTOME SIGNALING BY CSF3 G CSF 30 7.08e-01 8.34e-01 0.09820 -0.069900 -0.069000 5.07e-01 5.13e-01
REACTOME FCERI MEDIATED MAPK ACTIVATION 32 7.09e-01 8.34e-01 0.08920 0.028400 0.084500 7.81e-01 4.08e-01
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH 6 7.09e-01 8.34e-01 0.19600 0.194000 0.028800 4.10e-01 9.03e-01
REACTOME RHO GTPASES ACTIVATE CIT 19 7.09e-01 8.34e-01 0.09750 0.038200 -0.089700 7.73e-01 4.98e-01
REACTOME KILLING MECHANISMS 11 7.14e-01 8.38e-01 0.15900 -0.091300 -0.130000 6.00e-01 4.56e-01
REACTOME SIGNALING BY PDGF 56 7.17e-01 8.41e-01 0.05450 -0.042700 0.033900 5.81e-01 6.61e-01
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS 6 7.17e-01 8.41e-01 0.20900 -0.186000 -0.093600 4.29e-01 6.91e-01
REACTOME G ALPHA 12 13 SIGNALLING EVENTS 74 7.17e-01 8.41e-01 0.05960 0.052900 0.027500 4.32e-01 6.83e-01
REACTOME RHOB GTPASE CYCLE 67 7.19e-01 8.43e-01 0.05550 0.000111 0.055500 9.99e-01 4.33e-01
REACTOME STAT5 ACTIVATION 7 7.20e-01 8.43e-01 0.19500 0.164000 0.106000 4.52e-01 6.28e-01
REACTOME HYALURONAN UPTAKE AND DEGRADATION 11 7.21e-01 8.43e-01 0.12200 -0.082200 0.089500 6.37e-01 6.07e-01
REACTOME INTERLEUKIN 6 SIGNALING 11 7.21e-01 8.43e-01 0.15100 -0.060900 -0.138000 7.26e-01 4.27e-01
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION 7 7.22e-01 8.43e-01 0.15900 -0.151000 0.048900 4.89e-01 8.23e-01
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS 7 7.23e-01 8.43e-01 0.19600 0.116000 0.158000 5.96e-01 4.70e-01
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE 9 7.24e-01 8.43e-01 0.16000 0.155000 0.042000 4.21e-01 8.27e-01
REACTOME SYNTHESIS OF PG 8 7.24e-01 8.43e-01 0.18000 -0.154000 -0.093100 4.49e-01 6.49e-01
REACTOME INTERFERON SIGNALING 188 7.24e-01 8.43e-01 0.02930 0.019900 -0.021500 6.38e-01 6.11e-01
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM 20 7.25e-01 8.43e-01 0.10300 -0.009620 -0.102000 9.41e-01 4.29e-01
REACTOME SIGNAL TRANSDUCTION BY L1 20 7.26e-01 8.45e-01 0.09300 -0.028800 0.088500 8.23e-01 4.93e-01
REACTOME HEME DEGRADATION 15 7.27e-01 8.45e-01 0.11700 0.009320 0.117000 9.50e-01 4.32e-01
REACTOME ACYL CHAIN REMODELING OF CL 5 7.30e-01 8.48e-01 0.18300 -0.172000 0.063000 5.05e-01 8.07e-01
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY 5 7.32e-01 8.50e-01 0.20600 -0.203000 -0.035300 4.31e-01 8.91e-01
REACTOME PEPTIDE HORMONE METABOLISM 83 7.33e-01 8.50e-01 0.04370 -0.037300 0.022700 5.57e-01 7.21e-01
REACTOME THYROXINE BIOSYNTHESIS 10 7.33e-01 8.50e-01 0.15000 0.043200 0.144000 8.13e-01 4.31e-01
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION 20 7.38e-01 8.54e-01 0.10100 -0.100000 -0.014600 4.38e-01 9.10e-01
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES 35 7.38e-01 8.54e-01 0.08240 -0.074200 -0.035800 4.48e-01 7.14e-01
REACTOME CLEC7A INFLAMMASOME PATHWAY 6 7.39e-01 8.54e-01 0.16100 -0.140000 0.079300 5.54e-01 7.37e-01
REACTOME SIGNALING BY KIT IN DISEASE 20 7.39e-01 8.54e-01 0.09790 0.097800 0.003090 4.49e-01 9.81e-01
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE 22 7.39e-01 8.54e-01 0.09770 0.095600 0.020300 4.38e-01 8.69e-01
REACTOME CREATINE METABOLISM 10 7.40e-01 8.54e-01 0.14800 -0.142000 -0.041700 4.38e-01 8.19e-01
REACTOME SIGNALING BY NOTCH3 48 7.42e-01 8.56e-01 0.05560 0.036400 -0.042100 6.63e-01 6.14e-01
REACTOME LATE SARS COV 2 INFECTION EVENTS 67 7.44e-01 8.56e-01 0.05560 -0.054300 -0.012000 4.42e-01 8.66e-01
REACTOME SODIUM PROTON EXCHANGERS 7 7.44e-01 8.56e-01 0.18700 0.110000 0.151000 6.14e-01 4.90e-01
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION 34 7.44e-01 8.56e-01 0.08520 -0.055000 -0.065000 5.79e-01 5.12e-01
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 11 7.45e-01 8.56e-01 0.12300 -0.121000 0.024300 4.88e-01 8.89e-01
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY 23 7.46e-01 8.57e-01 0.09450 0.092300 0.020300 4.44e-01 8.66e-01
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN 5 7.46e-01 8.57e-01 0.18700 -0.187000 0.014400 4.69e-01 9.56e-01
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH 9 7.49e-01 8.59e-01 0.13800 0.138000 -0.012200 4.74e-01 9.49e-01
REACTOME REGULATION BY C FLIP 11 7.49e-01 8.59e-01 0.14000 0.132000 0.047400 4.50e-01 7.85e-01
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND 16 7.50e-01 8.60e-01 0.10900 0.108000 0.011300 4.54e-01 9.38e-01
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN 15 7.51e-01 8.60e-01 0.10300 -0.099000 0.026700 5.07e-01 8.58e-01
REACTOME INWARDLY RECTIFYING K CHANNELS 35 7.53e-01 8.61e-01 0.06690 -0.064400 0.018000 5.10e-01 8.54e-01
REACTOME LDL CLEARANCE 19 7.53e-01 8.61e-01 0.11200 -0.074500 -0.083300 5.74e-01 5.30e-01
REACTOME BETA OXIDATION OF PRISTANOYL COA 9 7.54e-01 8.62e-01 0.14700 0.144000 0.028200 4.54e-01 8.84e-01
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS 6 7.55e-01 8.63e-01 0.18000 -0.036700 -0.176000 8.76e-01 4.54e-01
REACTOME DEADENYLATION OF MRNA 25 7.56e-01 8.63e-01 0.09670 -0.072700 -0.063700 5.29e-01 5.82e-01
REACTOME SIGNALING BY SCF KIT 43 7.57e-01 8.63e-01 0.07320 0.042800 0.059300 6.27e-01 5.01e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING 30 7.58e-01 8.63e-01 0.08160 0.022000 0.078500 8.34e-01 4.57e-01
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 7.58e-01 8.63e-01 0.09960 -0.033300 0.093800 8.24e-01 5.29e-01
REACTOME ACTIVATION OF RAC1 12 7.59e-01 8.63e-01 0.11900 -0.119000 0.004100 4.77e-01 9.80e-01
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION 19 7.60e-01 8.64e-01 0.08540 -0.071500 0.046800 5.90e-01 7.24e-01
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES 17 7.60e-01 8.64e-01 0.09030 0.048900 -0.075900 7.27e-01 5.88e-01
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE 5 7.62e-01 8.66e-01 0.16800 0.073900 -0.150000 7.75e-01 5.60e-01
REACTOME HSF1 ACTIVATION 29 7.66e-01 8.68e-01 0.06790 -0.054600 0.040300 6.11e-01 7.08e-01
REACTOME RUNX3 REGULATES P14 ARF 10 7.66e-01 8.68e-01 0.14900 -0.109000 -0.102000 5.50e-01 5.76e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE 14 7.66e-01 8.68e-01 0.12300 0.058600 0.108000 7.04e-01 4.84e-01
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS 7 7.69e-01 8.70e-01 0.14300 0.042500 -0.136000 8.46e-01 5.32e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE 52 7.69e-01 8.70e-01 0.05630 -0.056300 -0.000587 4.83e-01 9.94e-01
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS 9 7.69e-01 8.70e-01 0.14600 -0.045900 -0.139000 8.12e-01 4.70e-01
REACTOME ANCHORING FIBRIL FORMATION 13 7.70e-01 8.70e-01 0.13000 -0.100000 -0.082300 5.32e-01 6.07e-01
REACTOME RAF ACTIVATION 33 7.70e-01 8.70e-01 0.07890 -0.070500 -0.035300 4.83e-01 7.26e-01
REACTOME EICOSANOID LIGAND BINDING RECEPTORS 14 7.72e-01 8.70e-01 0.12200 -0.060500 -0.106000 6.95e-01 4.94e-01
REACTOME BIOTIN TRANSPORT AND METABOLISM 10 7.72e-01 8.70e-01 0.14000 0.053400 0.130000 7.70e-01 4.78e-01
REACTOME ACYL CHAIN REMODELLING OF PI 17 7.73e-01 8.70e-01 0.08760 -0.046000 0.074600 7.43e-01 5.94e-01
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS 6 7.73e-01 8.70e-01 0.16000 0.014200 -0.159000 9.52e-01 4.99e-01
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS 16 7.73e-01 8.70e-01 0.11400 -0.061000 -0.096500 6.73e-01 5.04e-01
REACTOME KINESINS 59 7.74e-01 8.71e-01 0.05010 -0.049500 0.007710 5.11e-01 9.18e-01
REACTOME VXPX CARGO TARGETING TO CILIUM 20 7.76e-01 8.71e-01 0.09350 -0.017200 -0.091900 8.94e-01 4.77e-01
REACTOME C TYPE LECTIN RECEPTORS CLRS 133 7.76e-01 8.71e-01 0.03250 -0.031200 0.008960 5.34e-01 8.59e-01
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS 9 7.80e-01 8.75e-01 0.14800 0.070300 0.130000 7.15e-01 4.98e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING 6 7.80e-01 8.75e-01 0.15000 -0.045200 0.143000 8.48e-01 5.44e-01
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR 19 7.82e-01 8.77e-01 0.09020 0.001730 0.090100 9.90e-01 4.96e-01
REACTOME FLT3 SIGNALING IN DISEASE 28 7.83e-01 8.77e-01 0.06590 -0.049700 0.043300 6.49e-01 6.92e-01
REACTOME FASL CD95L SIGNALING 5 7.84e-01 8.77e-01 0.15700 -0.130000 0.087500 6.15e-01 7.35e-01
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS 20 7.84e-01 8.77e-01 0.09420 0.027900 0.089900 8.29e-01 4.86e-01
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 11 7.85e-01 8.77e-01 0.13500 -0.080600 -0.108000 6.43e-01 5.34e-01
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS 10 7.85e-01 8.77e-01 0.14000 -0.075300 -0.118000 6.80e-01 5.17e-01
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS 8 7.86e-01 8.77e-01 0.12200 -0.086100 0.086800 6.73e-01 6.71e-01
REACTOME NUCLEOTIDE SALVAGE 21 7.86e-01 8.77e-01 0.07590 0.043300 -0.062400 7.31e-01 6.21e-01
REACTOME PLASMA LIPOPROTEIN CLEARANCE 37 7.87e-01 8.77e-01 0.05690 -0.036000 0.044000 7.05e-01 6.43e-01
REACTOME SIGNALING BY FGFR4 IN DISEASE 11 7.89e-01 8.79e-01 0.12400 -0.120000 -0.032200 4.91e-01 8.53e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER 75 7.91e-01 8.81e-01 0.04540 0.004950 0.045200 9.41e-01 4.99e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE 20 7.93e-01 8.82e-01 0.09240 0.029000 0.087700 8.22e-01 4.97e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE 5 7.93e-01 8.82e-01 0.19000 0.172000 0.081000 5.07e-01 7.54e-01
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT 19 7.94e-01 8.82e-01 0.09740 -0.042600 -0.087600 7.48e-01 5.08e-01
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE 47 7.95e-01 8.83e-01 0.05780 -0.056900 -0.010200 5.00e-01 9.04e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 25 7.98e-01 8.86e-01 0.06700 -0.042200 0.052000 7.15e-01 6.53e-01
REACTOME THE ACTIVATION OF ARYLSULFATASES 8 8.01e-01 8.88e-01 0.13900 -0.027900 -0.136000 8.91e-01 5.06e-01
REACTOME REPRESSION OF WNT TARGET GENES 14 8.02e-01 8.89e-01 0.09480 0.017100 -0.093300 9.12e-01 5.46e-01
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS 6 8.04e-01 8.90e-01 0.13500 -0.082200 0.107000 7.27e-01 6.50e-01
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES 23 8.07e-01 8.93e-01 0.08800 0.068500 0.055200 5.70e-01 6.47e-01
REACTOME CRMPS IN SEMA3A SIGNALING 15 8.08e-01 8.93e-01 0.09400 0.094000 -0.000926 5.29e-01 9.95e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE 8 8.08e-01 8.93e-01 0.13200 -0.131000 -0.011100 5.20e-01 9.57e-01
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS 7 8.08e-01 8.93e-01 0.14900 -0.043700 -0.142000 8.41e-01 5.15e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ 6 8.10e-01 8.93e-01 0.15300 0.020800 0.152000 9.30e-01 5.20e-01
REACTOME SUPPRESSION OF APOPTOSIS 7 8.10e-01 8.93e-01 0.12200 -0.086800 0.085800 6.91e-01 6.94e-01
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION 7 8.11e-01 8.93e-01 0.12200 0.089700 -0.082500 6.81e-01 7.05e-01
REACTOME VOLTAGE GATED POTASSIUM CHANNELS 42 8.11e-01 8.93e-01 0.05640 -0.056400 -0.002380 5.27e-01 9.79e-01
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD 5 8.12e-01 8.93e-01 0.18700 -0.142000 -0.121000 5.82e-01 6.39e-01
REACTOME TRYPTOPHAN CATABOLISM 13 8.12e-01 8.93e-01 0.11200 0.050400 0.100000 7.53e-01 5.32e-01
REACTOME HDR THROUGH MMEJ ALT NHEJ 12 8.13e-01 8.93e-01 0.11900 -0.096900 -0.069700 5.61e-01 6.76e-01
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING 29 8.17e-01 8.96e-01 0.05890 -0.044700 0.038400 6.77e-01 7.20e-01
REACTOME SHC MEDIATED CASCADE FGFR4 19 8.17e-01 8.96e-01 0.08240 -0.004090 -0.082300 9.75e-01 5.35e-01
REACTOME ACTIVATION OF RAS IN B CELLS 5 8.17e-01 8.96e-01 0.14800 -0.141000 0.044500 5.85e-01 8.63e-01
REACTOME METHIONINE SALVAGE PATHWAY 6 8.18e-01 8.96e-01 0.15800 -0.054400 -0.149000 8.18e-01 5.28e-01
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM 21 8.19e-01 8.96e-01 0.08120 -0.016000 -0.079600 8.99e-01 5.28e-01
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND 14 8.19e-01 8.96e-01 0.09180 0.010100 -0.091200 9.48e-01 5.55e-01
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS 55 8.20e-01 8.97e-01 0.04920 -0.048800 -0.006350 5.32e-01 9.35e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K 7 8.21e-01 8.97e-01 0.14600 -0.051000 -0.136000 8.15e-01 5.32e-01
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS 25 8.22e-01 8.98e-01 0.07970 0.067700 0.042000 5.58e-01 7.16e-01
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN 11 8.23e-01 8.99e-01 0.10800 -0.108000 -0.013500 5.37e-01 9.38e-01
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING 14 8.24e-01 8.99e-01 0.09590 -0.095200 -0.011700 5.38e-01 9.39e-01
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR 19 8.25e-01 9.00e-01 0.07610 -0.074900 0.013300 5.72e-01 9.20e-01
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 11 8.27e-01 9.01e-01 0.09350 -0.078500 0.050800 6.52e-01 7.71e-01
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS 11 8.31e-01 9.04e-01 0.09570 -0.091300 0.028500 6.00e-01 8.70e-01
REACTOME HEME SIGNALING 47 8.31e-01 9.04e-01 0.05220 -0.010200 -0.051200 9.04e-01 5.44e-01
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR 8 8.32e-01 9.04e-01 0.13800 -0.112000 -0.080700 5.85e-01 6.93e-01
REACTOME PTK6 PROMOTES HIF1A STABILIZATION 6 8.33e-01 9.05e-01 0.15800 -0.131000 -0.088100 5.79e-01 7.09e-01
REACTOME SHC MEDIATED CASCADE FGFR3 17 8.36e-01 9.07e-01 0.09060 -0.081900 -0.038800 5.59e-01 7.82e-01
REACTOME RHOV GTPASE CYCLE 36 8.36e-01 9.07e-01 0.06060 -0.057500 -0.019300 5.51e-01 8.41e-01
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN 5 8.38e-01 9.08e-01 0.16200 -0.152000 -0.056500 5.55e-01 8.27e-01
REACTOME SIGNALING BY MST1 5 8.38e-01 9.08e-01 0.15600 -0.153000 -0.030200 5.53e-01 9.07e-01
REACTOME G ALPHA Z SIGNALLING EVENTS 47 8.39e-01 9.08e-01 0.04780 -0.047800 0.002050 5.71e-01 9.81e-01
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION 5 8.42e-01 9.10e-01 0.16000 -0.151000 -0.052000 5.59e-01 8.40e-01
REACTOME IRS MEDIATED SIGNALLING 46 8.42e-01 9.10e-01 0.05350 -0.049200 -0.020900 5.63e-01 8.06e-01
REACTOME SYNTHESIS OF KETONE BODIES 8 8.42e-01 9.10e-01 0.10300 0.069800 -0.076000 7.33e-01 7.10e-01
REACTOME ELASTIC FIBRE FORMATION 44 8.43e-01 9.10e-01 0.05640 -0.046800 -0.031300 5.91e-01 7.19e-01
REACTOME DNA DAMAGE REVERSAL 8 8.43e-01 9.10e-01 0.10300 0.064900 -0.080100 7.51e-01 6.95e-01
REACTOME MASTL FACILITATES MITOTIC PROGRESSION 10 8.44e-01 9.10e-01 0.11000 -0.028400 -0.106000 8.77e-01 5.60e-01
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE 9 8.46e-01 9.11e-01 0.09640 -0.059200 0.076000 7.58e-01 6.93e-01
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION 5 8.46e-01 9.11e-01 0.12900 -0.082500 0.098900 7.49e-01 7.02e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA 25 8.47e-01 9.11e-01 0.06660 0.008530 0.066100 9.41e-01 5.67e-01
REACTOME NEUROFASCIN INTERACTIONS 6 8.47e-01 9.11e-01 0.11700 0.082500 -0.083100 7.26e-01 7.24e-01
REACTOME WNT MEDIATED ACTIVATION OF DVL 8 8.48e-01 9.11e-01 0.11300 -0.113000 0.003680 5.82e-01 9.86e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 11 8.48e-01 9.11e-01 0.10400 -0.099900 -0.028300 5.66e-01 8.71e-01
REACTOME REGULATION OF NPAS4 GENE EXPRESSION 13 8.50e-01 9.13e-01 0.10200 -0.078800 -0.064800 6.23e-01 6.86e-01
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION 8 8.52e-01 9.14e-01 0.10700 0.105000 -0.019700 6.06e-01 9.23e-01
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION 7 8.54e-01 9.15e-01 0.10800 0.050900 -0.094900 8.15e-01 6.64e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS 185 8.54e-01 9.15e-01 0.02110 -0.018900 0.009420 6.58e-01 8.25e-01
REACTOME SIGNALING BY LEPTIN 11 8.56e-01 9.17e-01 0.09560 -0.095400 -0.006270 5.84e-01 9.71e-01
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB 10 8.56e-01 9.17e-01 0.10900 -0.100000 -0.041700 5.83e-01 8.19e-01
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 19 8.58e-01 9.17e-01 0.06360 0.038500 -0.050600 7.71e-01 7.03e-01
REACTOME SARS COV 2 MODULATES AUTOPHAGY 11 8.60e-01 9.19e-01 0.08810 0.017500 -0.086400 9.20e-01 6.20e-01
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION 12 8.60e-01 9.19e-01 0.09200 -0.013900 -0.091000 9.34e-01 5.85e-01
REACTOME RHOA GTPASE CYCLE 141 8.62e-01 9.20e-01 0.02550 -0.001080 0.025400 9.82e-01 6.02e-01
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS 63 8.63e-01 9.21e-01 0.03410 -0.026300 0.021700 7.18e-01 7.66e-01
REACTOME RA BIOSYNTHESIS PATHWAY 21 8.64e-01 9.21e-01 0.07350 0.066500 0.031400 5.98e-01 8.03e-01
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION 11 8.66e-01 9.22e-01 0.10400 -0.084300 -0.060900 6.28e-01 7.27e-01
REACTOME GLUCAGON TYPE LIGAND RECEPTORS 31 8.67e-01 9.24e-01 0.05160 -0.007780 0.051000 9.40e-01 6.23e-01
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL 25 8.68e-01 9.24e-01 0.05310 -0.042100 0.032300 7.16e-01 7.80e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4 15 8.69e-01 9.24e-01 0.08210 0.079100 0.021800 5.96e-01 8.84e-01
REACTOME DSCAM INTERACTIONS 11 8.70e-01 9.24e-01 0.08210 -0.076400 0.030000 6.61e-01 8.63e-01
REACTOME CELLULAR HEXOSE TRANSPORT 21 8.71e-01 9.25e-01 0.05720 -0.040200 0.040800 7.50e-01 7.46e-01
REACTOME PECAM1 INTERACTIONS 12 8.71e-01 9.25e-01 0.09400 0.037800 0.086000 8.21e-01 6.06e-01
REACTOME PTK6 EXPRESSION 5 8.73e-01 9.26e-01 0.12100 -0.114000 0.040400 6.60e-01 8.76e-01
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING 5 8.76e-01 9.28e-01 0.14600 -0.125000 -0.076400 6.29e-01 7.67e-01
REACTOME AZATHIOPRINE ADME 22 8.77e-01 9.29e-01 0.06810 -0.028700 -0.061800 8.16e-01 6.16e-01
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY 17 8.80e-01 9.32e-01 0.07430 -0.070600 -0.023200 6.14e-01 8.68e-01
REACTOME RHO GTPASES ACTIVATE IQGAPS 31 8.82e-01 9.33e-01 0.05330 0.052000 0.012000 6.17e-01 9.08e-01
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS 7 8.85e-01 9.36e-01 0.12000 0.092700 0.076700 6.71e-01 7.25e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL 14 8.86e-01 9.36e-01 0.08360 -0.044000 -0.071100 7.76e-01 6.45e-01
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS 30 8.87e-01 9.36e-01 0.05770 0.045400 0.035700 6.67e-01 7.35e-01
REACTOME INDUCTION OF CELL CELL FUSION 12 8.87e-01 9.36e-01 0.08800 -0.079600 -0.037500 6.33e-01 8.22e-01
REACTOME NICOTINAMIDE SALVAGING 19 8.90e-01 9.39e-01 0.06840 0.063000 0.026700 6.35e-01 8.41e-01
REACTOME SIGNALING BY NTRK3 TRKC 17 8.91e-01 9.39e-01 0.06190 0.060500 -0.013000 6.66e-01 9.26e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING 24 8.93e-01 9.40e-01 0.06200 0.052200 0.033400 6.58e-01 7.77e-01
REACTOME RIBAVIRIN ADME 11 8.96e-01 9.42e-01 0.08950 -0.077600 -0.044700 6.56e-01 7.97e-01
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS 7 8.96e-01 9.42e-01 0.10400 0.102000 0.018700 6.40e-01 9.32e-01
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX 5 8.97e-01 9.42e-01 0.13400 -0.109000 -0.078100 6.74e-01 7.62e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K 12 8.98e-01 9.42e-01 0.06810 0.060700 -0.031100 7.16e-01 8.52e-01
REACTOME SIGNALING BY ERYTHROPOIETIN 25 8.98e-01 9.42e-01 0.05850 0.051400 0.028000 6.57e-01 8.09e-01
REACTOME MITOCHONDRIAL UNCOUPLING 5 8.98e-01 9.42e-01 0.13400 -0.088600 -0.100000 7.32e-01 6.97e-01
REACTOME VLDLR INTERNALISATION AND DEGRADATION 16 8.99e-01 9.42e-01 0.06950 -0.066800 -0.019300 6.44e-01 8.94e-01
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7 7 8.99e-01 9.42e-01 0.11300 -0.078100 -0.081500 7.20e-01 7.09e-01
REACTOME CYP2E1 REACTIONS 10 9.01e-01 9.43e-01 0.09100 0.042900 0.080200 8.14e-01 6.60e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS 9 9.01e-01 9.43e-01 0.07570 -0.054500 0.052500 7.77e-01 7.85e-01
REACTOME SIGNAL ATTENUATION 10 9.04e-01 9.45e-01 0.07100 -0.055200 0.044700 7.63e-01 8.07e-01
REACTOME P38MAPK EVENTS 13 9.09e-01 9.49e-01 0.06400 -0.015500 0.062100 9.23e-01 6.98e-01
REACTOME GLYCOGEN SYNTHESIS 12 9.09e-01 9.49e-01 0.06390 -0.055900 0.031000 7.38e-01 8.52e-01
REACTOME ERYTHROPOIETIN ACTIVATES RAS 14 9.10e-01 9.50e-01 0.06080 -0.016500 0.058500 9.15e-01 7.05e-01
REACTOME ASPARTATE AND ASPARAGINE METABOLISM 11 9.12e-01 9.51e-01 0.08320 -0.048700 -0.067500 7.80e-01 6.98e-01
REACTOME RHOF GTPASE CYCLE 40 9.13e-01 9.52e-01 0.04250 -0.037500 -0.019900 6.81e-01 8.27e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR 24 9.14e-01 9.53e-01 0.05580 0.036100 0.042600 7.59e-01 7.18e-01
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS 7 9.15e-01 9.53e-01 0.09350 -0.091600 -0.018400 6.75e-01 9.33e-01
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND 55 9.16e-01 9.53e-01 0.02810 -0.020800 0.018900 7.90e-01 8.08e-01
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE 5 9.17e-01 9.53e-01 0.09890 0.096700 -0.020800 7.08e-01 9.36e-01
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR 11 9.18e-01 9.54e-01 0.07860 -0.068900 -0.037900 6.92e-01 8.28e-01
REACTOME CREB3 FACTORS ACTIVATE GENES 8 9.18e-01 9.54e-01 0.07280 -0.049100 0.053700 8.10e-01 7.92e-01
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN 13 9.22e-01 9.57e-01 0.06280 0.062700 0.001570 6.95e-01 9.92e-01
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI 5 9.23e-01 9.57e-01 0.10700 -0.103000 -0.025600 6.89e-01 9.21e-01
REACTOME PHASE 3 RAPID REPOLARISATION 8 9.24e-01 9.57e-01 0.08520 0.025700 0.081200 9.00e-01 6.91e-01
REACTOME ORGANIC CATION TRANSPORT 10 9.25e-01 9.57e-01 0.06620 0.064500 -0.014700 7.24e-01 9.36e-01
REACTOME SIGNALING BY ERBB2 ECD MUTANTS 16 9.25e-01 9.57e-01 0.06370 -0.040600 -0.049100 7.79e-01 7.34e-01
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION 11 9.26e-01 9.57e-01 0.07300 0.067700 0.027300 6.97e-01 8.75e-01
REACTOME EPHRIN SIGNALING 17 9.26e-01 9.57e-01 0.05800 0.054700 0.019200 6.96e-01 8.91e-01
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION 37 9.26e-01 9.57e-01 0.03720 -0.036900 -0.004940 6.98e-01 9.59e-01
REACTOME ORGANIC ANION TRANSPORTERS 10 9.27e-01 9.57e-01 0.06650 -0.065900 0.008670 7.18e-01 9.62e-01
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING 25 9.27e-01 9.57e-01 0.04030 -0.013200 0.038100 9.09e-01 7.41e-01
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 52 9.29e-01 9.58e-01 0.03220 0.030600 0.010100 7.02e-01 9.00e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES 11 9.31e-01 9.59e-01 0.06720 0.013700 0.065800 9.37e-01 7.06e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R 51 9.32e-01 9.59e-01 0.03270 -0.029900 -0.013200 7.12e-01 8.71e-01
REACTOME KERATAN SULFATE DEGRADATION 11 9.32e-01 9.59e-01 0.05810 -0.053900 0.021900 7.57e-01 9.00e-01
REACTOME SIGNALING BY FLT3 FUSION PROTEINS 19 9.33e-01 9.59e-01 0.05010 0.049300 0.008500 7.10e-01 9.49e-01
REACTOME SIGNAL AMPLIFICATION 31 9.38e-01 9.65e-01 0.04050 -0.035600 -0.019300 7.32e-01 8.52e-01
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION 9 9.40e-01 9.66e-01 0.06970 0.017200 0.067600 9.29e-01 7.26e-01
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA 115 9.43e-01 9.69e-01 0.01830 -0.001890 -0.018200 9.72e-01 7.36e-01
REACTOME REGULATION OF SIGNALING BY CBL 22 9.44e-01 9.69e-01 0.04500 0.040800 0.019000 7.41e-01 8.78e-01
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM 21 9.45e-01 9.69e-01 0.04010 -0.040000 0.003450 7.51e-01 9.78e-01
REACTOME HDL ASSEMBLY 8 9.46e-01 9.70e-01 0.07500 0.039500 0.063800 8.47e-01 7.55e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS 5 9.48e-01 9.71e-01 0.07800 0.015300 -0.076500 9.53e-01 7.67e-01
REACTOME MAPK3 ERK1 ACTIVATION 10 9.48e-01 9.71e-01 0.06300 -0.022200 -0.058900 9.03e-01 7.47e-01
REACTOME INTERLEUKIN 6 FAMILY SIGNALING 24 9.50e-01 9.71e-01 0.03320 0.015700 -0.029300 8.94e-01 8.04e-01
REACTOME MAPK1 ERK2 ACTIVATION 9 9.50e-01 9.71e-01 0.05390 0.026900 -0.046600 8.89e-01 8.09e-01
REACTOME INTERLEUKIN 9 SIGNALING 7 9.53e-01 9.73e-01 0.07040 0.067700 0.019300 7.57e-01 9.30e-01
REACTOME RHO GTPASES ACTIVATE KTN1 11 9.54e-01 9.73e-01 0.05140 -0.051300 0.001230 7.68e-01 9.94e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES 10 9.54e-01 9.73e-01 0.06250 0.042300 0.046000 8.17e-01 8.01e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS 27 9.54e-01 9.73e-01 0.03480 -0.033900 -0.007750 7.60e-01 9.44e-01
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE 8 9.58e-01 9.76e-01 0.05400 0.015400 -0.051800 9.40e-01 8.00e-01
REACTOME NEUROTRANSMITTER CLEARANCE 9 9.59e-01 9.76e-01 0.05530 0.054900 0.006500 7.76e-01 9.73e-01
REACTOME REGULATION OF KIT SIGNALING 16 9.59e-01 9.76e-01 0.04620 0.027100 0.037400 8.51e-01 7.96e-01
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY 26 9.60e-01 9.76e-01 0.03640 0.027000 0.024400 8.12e-01 8.29e-01
REACTOME SIGNALLING TO RAS 20 9.61e-01 9.76e-01 0.04100 0.028900 0.029100 8.23e-01 8.22e-01
REACTOME PLATELET HOMEOSTASIS 85 9.61e-01 9.76e-01 0.01950 -0.016500 -0.010400 7.92e-01 8.69e-01
REACTOME ABACAVIR ADME 9 9.62e-01 9.76e-01 0.05050 -0.050100 0.005910 7.94e-01 9.75e-01
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS 10 9.62e-01 9.76e-01 0.05240 0.050700 0.013200 7.81e-01 9.42e-01
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER 5 9.63e-01 9.77e-01 0.07120 -0.011500 -0.070200 9.65e-01 7.86e-01
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS 21 9.64e-01 9.77e-01 0.03670 -0.033200 -0.015700 7.92e-01 9.01e-01
REACTOME RHOU GTPASE CYCLE 37 9.66e-01 9.78e-01 0.02820 0.019300 0.020500 8.39e-01 8.29e-01
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS 122 9.67e-01 9.79e-01 0.01210 -0.011100 0.004780 8.32e-01 9.27e-01
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS 16 9.70e-01 9.81e-01 0.03320 0.005590 -0.032700 9.69e-01 8.21e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE 5 9.72e-01 9.83e-01 0.05590 -0.053700 0.015700 8.35e-01 9.52e-01
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES 16 9.77e-01 9.88e-01 0.03440 0.026800 0.021600 8.53e-01 8.81e-01
REACTOME IRS ACTIVATION 5 9.81e-01 9.91e-01 0.04410 0.036900 -0.024100 8.86e-01 9.26e-01
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX 15 9.81e-01 9.91e-01 0.02520 -0.021600 0.013000 8.85e-01 9.31e-01
REACTOME REGULATION OF PTEN MRNA TRANSLATION 9 9.83e-01 9.91e-01 0.03850 -0.035800 -0.014100 8.52e-01 9.42e-01
REACTOME SYNDECAN INTERACTIONS 25 9.84e-01 9.91e-01 0.02260 0.009450 0.020500 9.35e-01 8.59e-01
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING 13 9.84e-01 9.91e-01 0.03070 0.027900 0.012800 8.62e-01 9.36e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS 11 9.84e-01 9.91e-01 0.03470 0.023100 0.025900 8.94e-01 8.82e-01
REACTOME SOS MEDIATED SIGNALLING 7 9.86e-01 9.92e-01 0.03210 0.022500 -0.022900 9.18e-01 9.17e-01
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT 5 9.86e-01 9.92e-01 0.04810 0.038300 0.029100 8.82e-01 9.10e-01
REACTOME INTERLEUKIN 15 SIGNALING 13 9.88e-01 9.92e-01 0.02720 -0.011100 -0.024800 9.45e-01 8.77e-01
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS 5 9.89e-01 9.94e-01 0.03250 0.021600 -0.024300 9.33e-01 9.25e-01
REACTOME LAMININ INTERACTIONS 28 9.92e-01 9.95e-01 0.01400 0.002130 0.013800 9.84e-01 8.99e-01
REACTOME DISINHIBITION OF SNARE FORMATION 5 9.92e-01 9.95e-01 0.02770 0.023100 -0.015300 9.29e-01 9.53e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42 19 9.93e-01 9.95e-01 0.01660 -0.015800 -0.004960 9.05e-01 9.70e-01
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII 15 9.93e-01 9.95e-01 0.01520 -0.014000 0.006050 9.25e-01 9.68e-01
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS 30 9.94e-01 9.95e-01 0.00981 0.005870 -0.007860 9.56e-01 9.41e-01
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES 37 9.96e-01 9.96e-01 0.00884 -0.008810 -0.000714 9.26e-01 9.94e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES 43 9.98e-01 9.98e-01 0.00478 -0.003520 0.003230 9.68e-01 9.71e-01


Detailed Gene set reports


REACTOME_OLFACTORY_SIGNALING_PATHWAY

REACTOME_OLFACTORY_SIGNALING_PATHWAY
metric value
setSize 313
pMANOVA 1.53e-48
p.adjustMANOVA 2.51e-45
s.dist 0.533
s.Estill 0.463
s.Novakovic 0.265
p.Estill 3.58e-45
p.Novakovic 8.15e-16




Top 20 genes
Gene Estill Novakovic
OR1J4 2660 1880
OR10K1 2707 1814
OR8H1 2558 1899
OR2A4 2485 1917
OR5B2 2720 1636
OR2J3 2360 1830
OR9I1 2135 1869
OR6K3 2202 1806
OR10T2 2501 1585
OR11H4 2227 1634
OR7G1 2520 1438
OR7D2 2593 1325
OR52E6 1930 1773
OR2L2 2716 1206
OR4A15 1635 1771
OR6Q1 2116 1354
OR4A47 1690 1628
OR2S2 1858 1384
OR7C1 1848 1366
OR4S1 1913 1282

Click HERE to show all gene set members

All member genes
Estill Novakovic
ADCY3 -5312.0 -4397.0
ANO2 -4014.0 -4062.0
CNGA4 -4003.0 -6797.0
CNGB1 -10820.0 -9058.0
EBF1 -1424.0 -8941.0
GNAL -10428.0 -9798.0
GNB1 -5413.0 -5802.0
GNG13 -5498.0 -8674.0
LDB1 -7790.0 -15978.0
LHX2 -4692.0 -4844.0
OR10A2 -4155.0 1760.0
OR10A3 2597.0 -11202.0
OR10A4 1126.0 -9144.0
OR10A5 -10695.0 -14263.0
OR10A6 -10967.0 -8447.0
OR10AD1 1195.0 -1292.0
OR10C1 260.0 -7536.0
OR10G2 2351.0 535.0
OR10G3 -800.0 973.0
OR10G4 1876.0 -13677.0
OR10G7 -12822.0 1327.0
OR10G8 1356.0 1278.0
OR10G9 2452.0 -428.0
OR10H1 2098.0 124.0
OR10H2 -4135.0 -706.0
OR10H3 8.0 1501.0
OR10H4 2483.0 -2744.0
OR10H5 -3793.0 -2285.0
OR10J1 2446.0 754.0
OR10J3 2712.0 -555.0
OR10J5 659.0 -1168.0
OR10K1 2707.0 1814.0
OR10K2 -1339.0 -13045.0
OR10P1 -10051.0 -8557.0
OR10Q1 -2024.0 1187.0
OR10S1 1987.0 -16597.0
OR10T2 2501.0 1585.0
OR10V1 2508.0 -5760.0
OR10W1 1464.0 -16155.0
OR10X1 717.0 -11693.0
OR10Z1 -3452.0 -13940.0
OR11A1 1578.0 -524.0
OR11G2 2179.0 -15274.0
OR11H4 2227.0 1634.0
OR11H6 -1073.0 1740.0
OR11L1 1863.0 -10808.0
OR12D2 -3166.0 1052.0
OR12D3 -4842.0 -3977.0
OR13A1 2420.0 -15467.0
OR13C3 -4092.0 -7533.0
OR13C4 217.0 -9978.0
OR13C8 1206.0 -3526.0
OR13F1 -11415.0 -17243.0
OR13J1 -4721.0 -652.0
OR14A16 -10332.0 -15688.0
OR14C36 2710.0 -298.0
OR14I1 1430.0 -698.0
OR14J1 1244.0 -732.0
OR1A1 1607.0 -7920.0
OR1A2 -1456.0 -6897.0
OR1B1 917.0 1227.0
OR1C1 -10221.0 -7498.0
OR1D2 2699.0 -31.0
OR1D4 -2277.5 -2588.5
OR1D5 -2277.5 -2588.5
OR1E1 511.0 1846.0
OR1E2 -11344.0 -179.0
OR1F1 -9869.0 -3008.0
OR1G1 2226.0 668.0
OR1I1 460.0 1218.0
OR1J1 -12868.0 -14631.0
OR1J2 2002.0 -13451.0
OR1J4 2660.0 1880.0
OR1K1 920.0 -10882.0
OR1L3 -198.0 743.0
OR1L6 -1299.0 -9641.0
OR1M1 518.0 -6946.0
OR1N1 991.0 722.0
OR1Q1 1757.0 777.0
OR1S1 -13041.0 -13668.0
OR1S2 -1652.0 -3516.0
OR2A12 2562.0 -8881.0
OR2A14 -16419.0 304.0
OR2A2 2717.0 -442.0
OR2A25 -5157.0 1926.0
OR2A4 2485.0 1917.0
OR2A5 925.0 1808.0
OR2AE1 595.0 1087.0
OR2AG1 758.0 1619.0
OR2AG2 1552.0 1463.0
OR2AT4 1807.0 -17185.0
OR2B11 1521.0 -2229.0
OR2B2 2367.0 989.0
OR2B3 532.0 -768.0
OR2C1 -3425.0 1544.0
OR2C3 660.0 -3080.0
OR2D2 1266.0 1833.0
OR2D3 -8245.0 -10367.0
OR2F1 -4392.0 -15432.0
OR2F2 2543.0 -14926.0
OR2G2 2611.0 -6503.0
OR2G3 -4504.0 -2354.0
OR2G6 2022.0 -15652.0
OR2H1 2125.0 -9260.0
OR2H2 2165.0 -11841.0
OR2J2 -5340.0 -2537.0
OR2J3 2360.0 1830.0
OR2K2 2128.0 -1310.0
OR2L13 1291.0 -1618.0
OR2L2 2716.0 1206.0
OR2L3 -15405.0 150.0
OR2L8 -16482.0 1418.0
OR2M2 2201.0 -1319.0
OR2M3 -15006.0 -1728.0
OR2M4 -14805.0 -16758.0
OR2M5 -5852.0 1330.0
OR2M7 2601.0 -11466.0
OR2S2 1858.0 1384.0
OR2T1 -3742.0 -16505.0
OR2T11 182.0 -12892.0
OR2T12 2571.0 -14561.0
OR2T27 2127.0 -3578.0
OR2T29 1230.0 525.0
OR2T3 2335.0 -7013.0
OR2T33 -1678.0 1413.0
OR2T34 2517.0 -8406.0
OR2T4 -16400.0 1552.0
OR2T5 1169.0 892.0
OR2T6 2023.0 -10813.0
OR2T8 2691.0 -16023.0
OR2V2 1889.0 -2575.0
OR2W3 -6872.0 -16057.0
OR2Y1 1603.0 -1243.0
OR2Z1 -1451.0 1647.0
OR3A1 1509.0 -10625.0
OR3A2 86.0 -14685.0
OR3A3 1839.0 -2519.0
OR4A15 1635.0 1771.0
OR4A47 1690.0 1628.0
OR4A5 -4568.0 -17303.0
OR4B1 -1277.0 -6145.0
OR4C13 -8770.0 1272.0
OR4C15 501.0 1437.0
OR4C16 -16300.0 1874.0
OR4C45 -8060.0 1168.0
OR4C6 1428.0 1498.0
OR4D1 2322.0 -9334.0
OR4D10 -1978.0 -6837.0
OR4D11 358.0 -15980.0
OR4D2 892.0 -6044.0
OR4D5 -9702.0 1422.0
OR4D6 1822.0 -11139.0
OR4D9 -8428.0 -7459.0
OR4E2 1049.0 1360.0
OR4F15 2587.0 -13907.0
OR4F5 -7932.0 -24.0
OR4F6 1881.0 -2907.0
OR4K1 -11878.0 -936.0
OR4K13 -15647.0 1398.0
OR4K14 -7446.0 1143.0
OR4K15 -13488.0 1887.0
OR4K17 -4220.0 -5702.0
OR4K2 -16211.0 -8352.0
OR4N2 -4461.0 1535.0
OR4N5 -2805.0 1132.0
OR4Q3 2243.0 -813.0
OR4S1 1913.0 1282.0
OR4S2 -16297.0 1704.0
OR4X1 -2068.0 -550.0
OR51A2 -3439.0 -16915.0
OR51A7 -3619.0 1530.0
OR51B2 -13004.0 -459.0
OR51B4 -16230.0 -15143.0
OR51B5 78.0 -13178.0
OR51B6 2692.0 -12456.0
OR51D1 1611.0 -4494.0
OR51E1 2223.0 -13534.0
OR51E2 -2892.0 -13003.0
OR51F1 1387.0 -753.0
OR51F2 -127.0 -6012.0
OR51G1 2378.0 -2176.0
OR51G2 -16367.0 1350.0
OR51I1 -863.0 -4447.0
OR51I2 2209.0 -17033.0
OR51L1 2702.0 -10582.0
OR51M1 2524.0 -16938.0
OR51Q1 -7968.0 -14277.0
OR51S1 1551.0 -1617.0
OR51T1 -3685.0 1286.0
OR51V1 2726.0 -4260.0
OR52A1 -4724.0 -9935.0
OR52B2 1638.0 -12571.0
OR52B6 2445.0 -4776.0
OR52D1 -4496.0 -13113.0
OR52E2 -13901.0 -8442.0
OR52E4 -5984.0 -17297.0
OR52E6 1930.0 1773.0
OR52H1 -4035.0 -16339.0
OR52I1 -2406.0 -16674.0
OR52I2 2545.0 579.0
OR52J3 2481.0 -1028.0
OR52K1 1984.0 -14499.0
OR52K2 2713.0 -7314.0
OR52L1 -4255.0 -1362.0
OR52M1 2531.0 -17008.0
OR52N1 -179.0 -6838.0
OR52N2 2072.0 -635.0
OR52N5 1377.0 1716.0
OR52R1 1962.0 -13851.0
OR52W1 885.0 -15931.0
OR56A1 -4863.0 1653.0
OR56A3 -16154.0 -628.0
OR56A4 594.0 1339.0
OR56B1 -10350.0 -17101.0
OR56B4 -649.0 1868.0
OR5A1 -1685.0 -581.0
OR5A2 512.0 1243.0
OR5AK2 1946.0 -1305.0
OR5AN1 2489.0 -17208.0
OR5AP2 -3127.0 -11973.0
OR5AR1 -1874.0 -14269.0
OR5AS1 -13153.0 938.0
OR5AU1 2200.0 -5359.0
OR5B12 -146.0 -13825.0
OR5B17 -705.0 -17240.0
OR5B2 2720.0 1636.0
OR5B21 -1069.0 -15161.0
OR5B3 -6800.0 291.0
OR5C1 2017.0 109.0
OR5D13 -15159.0 -50.0
OR5D14 -16195.0 -11181.0
OR5D16 -10793.0 -7621.0
OR5D18 -16500.0 -9293.0
OR5H1 -3524.0 1179.0
OR5I1 -16368.0 -2601.0
OR5K2 -15030.0 -17159.0
OR5L1 -16220.0 -3085.0
OR5L2 -16386.0 -2556.0
OR5M1 2646.0 -17284.0
OR5M10 -1650.0 -2753.0
OR5M11 883.0 -1423.0
OR5M8 2505.0 413.0
OR5M9 -3553.0 -3848.0
OR5P2 -8117.0 1454.0
OR5P3 -378.0 -543.0
OR5T2 -4625.0 1151.0
OR5V1 -3651.0 -5398.0
OR6A2 -8564.0 -1796.0
OR6B1 1112.0 -7377.0
OR6B2 -6748.0 1755.0
OR6B3 1232.0 60.0
OR6C1 2129.0 -205.0
OR6C3 -2819.0 1583.0
OR6C4 2249.0 -7679.0
OR6C70 575.0 -10656.0
OR6C74 -9292.0 -9113.0
OR6F1 -13642.0 -3801.0
OR6K2 -1150.0 -14344.0
OR6K3 2202.0 1806.0
OR6K6 2237.0 -2185.0
OR6M1 1983.0 -7028.0
OR6N1 2667.0 -1963.0
OR6N2 828.0 493.0
OR6P1 579.0 -12031.0
OR6Q1 2116.0 1354.0
OR6S1 940.0 -3598.0
OR6T1 2401.0 -5465.0
OR6V1 1378.0 1480.0
OR6X1 2675.0 -10365.0
OR6Y1 1679.0 -8377.0
OR7A10 -9133.0 1801.0
OR7A17 -10382.0 813.0
OR7A5 1491.0 -11643.0
OR7C1 1848.0 1366.0
OR7C2 -2264.0 1254.0
OR7D2 2593.0 1325.0
OR7D4 -4058.0 695.0
OR7E24 -8241.0 1850.0
OR7G1 2520.0 1438.0
OR7G2 -12727.0 158.0
OR7G3 -2001.0 701.0
OR8A1 -16143.0 -4964.0
OR8B12 -7887.0 -15412.0
OR8B2 -561.0 -15151.0
OR8B3 2349.0 -16401.0
OR8B4 2402.0 -8112.0
OR8B8 453.0 899.0
OR8D1 2482.0 -11633.0
OR8D2 -4010.0 -13722.0
OR8D4 834.0 -11057.0
OR8G1 1214.0 -13130.0
OR8G5 -1607.0 -15856.0
OR8H1 2558.0 1899.0
OR8H2 -14383.0 1712.0
OR8H3 -16453.0 122.0
OR8I2 -15599.0 1925.0
OR8J3 -1634.0 -12853.0
OR8K5 -13054.0 -12073.0
OR8S1 -1573.0 -7705.0
OR8U3 1489.0 -17264.0
OR8U8 -4705.0 -2641.0
OR9A2 -4850.0 365.0
OR9A4 2325.0 -7360.0
OR9G1 -3502.5 -6630.5
OR9G4 145.0 -12582.0
OR9G9 -3502.5 -6630.5
OR9I1 2135.0 1869.0
OR9K2 -6936.0 -12740.0
OR9Q1 111.0 1050.0
OR9Q2 668.0 1733.0
REEP1 -7132.0 -14378.0
RTP1 -63.0 -2577.0
RTP2 220.0 -1142.0



REACTOME_SENSORY_PERCEPTION

REACTOME_SENSORY_PERCEPTION
metric value
setSize 512
pMANOVA 2.82e-32
p.adjustMANOVA 2.32e-29
s.dist 0.347
s.Estill 0.275
s.Novakovic 0.211
p.Estill 1.53e-26
p.Novakovic 3.48e-16




Top 20 genes
Gene Estill Novakovic
OR1J4 2660 1880
OR10K1 2707 1814
OR8H1 2558 1899
OR2A4 2485 1917
OR5B2 2720 1636
OR2J3 2360 1830
OR9I1 2135 1869
OR6K3 2202 1806
OR10T2 2501 1585
OR11H4 2227 1634
OR7G1 2520 1438
STRC 2327 1509
PNLIP 2081 1655
OR7D2 2593 1325
OR52E6 1930 1773
OR2L2 2716 1206
OR4A15 1635 1771
OR6Q1 2116 1354
OR4A47 1690 1628
OR2S2 1858 1384

Click HERE to show all gene set members

All member genes
Estill Novakovic
ABCA4 1886.0 -5121.0
ACTB -14421.0 -17178.0
ACTG1 -14449.0 -15547.0
ADCY3 -5312.0 -4397.0
AGRN -11173.0 -7188.0
AKR1B10 -1752.0 -188.0
AKR1C1 49.0 -6686.0
AKR1C3 1902.0 900.0
AKR1C4 -10147.0 -7980.0
ANO2 -4014.0 -4062.0
APOA1 -7264.0 -5044.0
APOA2 932.0 -137.0
APOA4 -7298.0 -4032.0
APOB 340.0 -10566.0
APOC2 -14351.0 -10374.0
APOC3 -12956.0 -6633.0
APOE -5441.0 -1114.0
APOM 484.0 437.0
ATP2B1 -12712.0 -13267.0
ATP2B2 -7064.0 -2307.0
BCO1 966.0 -5968.0
BCO2 -5429.0 607.0
BSN -4513.0 -4235.0
CABP1 -4495.0 -12606.0
CABP2 -13388.0 168.0
CACNA1D -1450.0 -5227.0
CACNA2D2 -11574.0 -3555.0
CACNB2 -6777.0 -3563.0
CALHM1 -2561.0 475.0
CALHM3 -3260.0 1289.0
CALM1 -11935.0 -10428.0
CAMKMT -9718.0 -8857.0
CAPZA1 -3504.0 -10215.0
CAPZA2 -13595.0 -14422.0
CAPZB 383.0 -902.0
CDH23 -8567.0 -4361.0
CHRNA10 -7714.0 -1231.0
CHRNA9 2058.0 -2615.0
CIB2 -14990.0 -10581.0
CLIC5 -1035.0 -14032.0
CLPS -9096.0 -1918.0
CNGA1 -2403.0 -8037.0
CNGA4 -4003.0 -6797.0
CNGB1 -10820.0 -9058.0
CTBP2 -1805.0 -5404.0
CYP4V2 -9645.0 -14802.0
DHRS3 -3864.0 -9719.0
DHRS9 -1965.0 -3060.0
DNAJC5 -4456.0 -3846.0
EBF1 -1424.0 -8941.0
EPB41L1 -11441.0 -5757.0
EPB41L3 -5023.0 -10844.0
EPS8 -13279.0 -12962.0
EPS8L2 -12303.0 -6634.0
ESPN -9811.0 -13832.0
ESPNL -4889.0 -571.0
EZR -7988.0 -7897.0
FNTA -15247.0 -12298.0
FNTB -6304.0 -19.0
FSCN2 -16270.0 -15878.0
GNAL -10428.0 -9798.0
GNAT1 -10588.0 784.0
GNB1 -5413.0 -5802.0
GNB3 -8840.0 -5034.0
GNB5 -5461.0 -7062.0
GNG13 -5498.0 -8674.0
GNGT1 -16495.0 926.0
GPC1 -11109.0 -7559.0
GPC2 -11132.0 -11236.0
GPC5 -15441.0 -6932.0
GPC6 -3948.0 -2826.0
GPIHBP1 -14311.0 -9287.0
GRK1 -13365.0 -9361.0
GRK4 -8742.0 -3352.0
GRK7 -1738.0 -3418.0
GRM1 -15086.0 -9470.0
GRM4 -14517.0 -2701.0
GRXCR1 -10211.0 -12993.0
GRXCR2 2244.0 -11306.0
GSN -8149.0 -7076.0
GUCA1A -83.0 -416.0
GUCA1B 2516.0 -654.0
GUCA1C 1447.0 -2188.0
GUCY2D -420.0 -4805.0
HSD17B1 -7977.0 -4761.0
HSD17B6 -10814.0 -8322.0
HSPG2 -5450.0 -3105.0
ITPR3 -9861.0 -4377.0
KCNJ2 -14268.0 -14128.0
KCNMA1 707.0 -6428.0
KCNMB1 -4951.0 -1351.0
KCNN2 -12762.0 -12569.0
KCNQ4 -14319.0 -7462.0
LDB1 -7790.0 -15978.0
LDLR -8347.0 -4660.0
LHFPL5 -4998.0 -5352.0
LHX2 -4692.0 -4844.0
LPL -14501.0 -4220.0
LRAT -7509.0 -11355.0
LRP1 -7245.0 -1430.0
LRP10 -4981.0 -12708.0
LRP12 -8046.0 -5181.0
LRP2 -8502.0 -10780.0
LRP8 -6319.0 -10199.0
LRRC52 -8905.0 -5978.0
METAP1 -15948.0 -8686.0
METAP2 -12175.0 -11229.0
MYH9 -3823.0 -1010.0
MYO15A -8649.0 -801.0
MYO1C -12324.0 -10305.0
MYO3A -5376.0 -12393.0
MYO3B -227.0 -2480.0
MYO7A -9122.0 -704.0
NAPEPLD -5242.0 -15208.0
NMT1 590.0 -3093.0
NMT2 -14307.0 -6409.0
OPN1SW 1884.0 -2781.0
OR10A2 -4155.0 1760.0
OR10A3 2597.0 -11202.0
OR10A4 1126.0 -9144.0
OR10A5 -10695.0 -14263.0
OR10A6 -10967.0 -8447.0
OR10AD1 1195.0 -1292.0
OR10C1 260.0 -7536.0
OR10G2 2351.0 535.0
OR10G3 -800.0 973.0
OR10G4 1876.0 -13677.0
OR10G7 -12822.0 1327.0
OR10G8 1356.0 1278.0
OR10G9 2452.0 -428.0
OR10H1 2098.0 124.0
OR10H2 -4135.0 -706.0
OR10H3 8.0 1501.0
OR10H4 2483.0 -2744.0
OR10H5 -3793.0 -2285.0
OR10J1 2446.0 754.0
OR10J3 2712.0 -555.0
OR10J5 659.0 -1168.0
OR10K1 2707.0 1814.0
OR10K2 -1339.0 -13045.0
OR10P1 -10051.0 -8557.0
OR10Q1 -2024.0 1187.0
OR10S1 1987.0 -16597.0
OR10T2 2501.0 1585.0
OR10V1 2508.0 -5760.0
OR10W1 1464.0 -16155.0
OR10X1 717.0 -11693.0
OR10Z1 -3452.0 -13940.0
OR11A1 1578.0 -524.0
OR11G2 2179.0 -15274.0
OR11H4 2227.0 1634.0
OR11H6 -1073.0 1740.0
OR11L1 1863.0 -10808.0
OR12D2 -3166.0 1052.0
OR12D3 -4842.0 -3977.0
OR13A1 2420.0 -15467.0
OR13C3 -4092.0 -7533.0
OR13C4 217.0 -9978.0
OR13C8 1206.0 -3526.0
OR13F1 -11415.0 -17243.0
OR13J1 -4721.0 -652.0
OR14A16 -10332.0 -15688.0
OR14C36 2710.0 -298.0
OR14I1 1430.0 -698.0
OR14J1 1244.0 -732.0
OR1A1 1607.0 -7920.0
OR1A2 -1456.0 -6897.0
OR1B1 917.0 1227.0
OR1C1 -10221.0 -7498.0
OR1D2 2699.0 -31.0
OR1D4 -2277.5 -2588.5
OR1D5 -2277.5 -2588.5
OR1E1 511.0 1846.0
OR1E2 -11344.0 -179.0
OR1F1 -9869.0 -3008.0
OR1G1 2226.0 668.0
OR1I1 460.0 1218.0
OR1J1 -12868.0 -14631.0
OR1J2 2002.0 -13451.0
OR1J4 2660.0 1880.0
OR1K1 920.0 -10882.0
OR1L3 -198.0 743.0
OR1L6 -1299.0 -9641.0
OR1M1 518.0 -6946.0
OR1N1 991.0 722.0
OR1Q1 1757.0 777.0
OR1S1 -13041.0 -13668.0
OR1S2 -1652.0 -3516.0
OR2A12 2562.0 -8881.0
OR2A14 -16419.0 304.0
OR2A2 2717.0 -442.0
OR2A25 -5157.0 1926.0
OR2A4 2485.0 1917.0
OR2A5 925.0 1808.0
OR2AE1 595.0 1087.0
OR2AG1 758.0 1619.0
OR2AG2 1552.0 1463.0
OR2AT4 1807.0 -17185.0
OR2B11 1521.0 -2229.0
OR2B2 2367.0 989.0
OR2B3 532.0 -768.0
OR2C1 -3425.0 1544.0
OR2C3 660.0 -3080.0
OR2D2 1266.0 1833.0
OR2D3 -8245.0 -10367.0
OR2F1 -4392.0 -15432.0
OR2F2 2543.0 -14926.0
OR2G2 2611.0 -6503.0
OR2G3 -4504.0 -2354.0
OR2G6 2022.0 -15652.0
OR2H1 2125.0 -9260.0
OR2H2 2165.0 -11841.0
OR2J2 -5340.0 -2537.0
OR2J3 2360.0 1830.0
OR2K2 2128.0 -1310.0
OR2L13 1291.0 -1618.0
OR2L2 2716.0 1206.0
OR2L3 -15405.0 150.0
OR2L8 -16482.0 1418.0
OR2M2 2201.0 -1319.0
OR2M3 -15006.0 -1728.0
OR2M4 -14805.0 -16758.0
OR2M5 -5852.0 1330.0
OR2M7 2601.0 -11466.0
OR2S2 1858.0 1384.0
OR2T1 -3742.0 -16505.0
OR2T11 182.0 -12892.0
OR2T12 2571.0 -14561.0
OR2T27 2127.0 -3578.0
OR2T29 1230.0 525.0
OR2T3 2335.0 -7013.0
OR2T33 -1678.0 1413.0
OR2T34 2517.0 -8406.0
OR2T4 -16400.0 1552.0
OR2T5 1169.0 892.0
OR2T6 2023.0 -10813.0
OR2T8 2691.0 -16023.0
OR2V2 1889.0 -2575.0
OR2W3 -6872.0 -16057.0
OR2Y1 1603.0 -1243.0
OR2Z1 -1451.0 1647.0
OR3A1 1509.0 -10625.0
OR3A2 86.0 -14685.0
OR3A3 1839.0 -2519.0
OR4A15 1635.0 1771.0
OR4A47 1690.0 1628.0
OR4A5 -4568.0 -17303.0
OR4B1 -1277.0 -6145.0
OR4C13 -8770.0 1272.0
OR4C15 501.0 1437.0
OR4C16 -16300.0 1874.0
OR4C45 -8060.0 1168.0
OR4C6 1428.0 1498.0
OR4D1 2322.0 -9334.0
OR4D10 -1978.0 -6837.0
OR4D11 358.0 -15980.0
OR4D2 892.0 -6044.0
OR4D5 -9702.0 1422.0
OR4D6 1822.0 -11139.0
OR4D9 -8428.0 -7459.0
OR4E2 1049.0 1360.0
OR4F15 2587.0 -13907.0
OR4F5 -7932.0 -24.0
OR4F6 1881.0 -2907.0
OR4K1 -11878.0 -936.0
OR4K13 -15647.0 1398.0
OR4K14 -7446.0 1143.0
OR4K15 -13488.0 1887.0
OR4K17 -4220.0 -5702.0
OR4K2 -16211.0 -8352.0
OR4N2 -4461.0 1535.0
OR4N5 -2805.0 1132.0
OR4Q3 2243.0 -813.0
OR4S1 1913.0 1282.0
OR4S2 -16297.0 1704.0
OR4X1 -2068.0 -550.0
OR51A2 -3439.0 -16915.0
OR51A7 -3619.0 1530.0
OR51B2 -13004.0 -459.0
OR51B4 -16230.0 -15143.0
OR51B5 78.0 -13178.0
OR51B6 2692.0 -12456.0
OR51D1 1611.0 -4494.0
OR51E1 2223.0 -13534.0
OR51E2 -2892.0 -13003.0
OR51F1 1387.0 -753.0
OR51F2 -127.0 -6012.0
OR51G1 2378.0 -2176.0
OR51G2 -16367.0 1350.0
OR51I1 -863.0 -4447.0
OR51I2 2209.0 -17033.0
OR51L1 2702.0 -10582.0
OR51M1 2524.0 -16938.0
OR51Q1 -7968.0 -14277.0
OR51S1 1551.0 -1617.0
OR51T1 -3685.0 1286.0
OR51V1 2726.0 -4260.0
OR52A1 -4724.0 -9935.0
OR52B2 1638.0 -12571.0
OR52B6 2445.0 -4776.0
OR52D1 -4496.0 -13113.0
OR52E2 -13901.0 -8442.0
OR52E4 -5984.0 -17297.0
OR52E6 1930.0 1773.0
OR52H1 -4035.0 -16339.0
OR52I1 -2406.0 -16674.0
OR52I2 2545.0 579.0
OR52J3 2481.0 -1028.0
OR52K1 1984.0 -14499.0
OR52K2 2713.0 -7314.0
OR52L1 -4255.0 -1362.0
OR52M1 2531.0 -17008.0
OR52N1 -179.0 -6838.0
OR52N2 2072.0 -635.0
OR52N5 1377.0 1716.0
OR52R1 1962.0 -13851.0
OR52W1 885.0 -15931.0
OR56A1 -4863.0 1653.0
OR56A3 -16154.0 -628.0
OR56A4 594.0 1339.0
OR56B1 -10350.0 -17101.0
OR56B4 -649.0 1868.0
OR5A1 -1685.0 -581.0
OR5A2 512.0 1243.0
OR5AK2 1946.0 -1305.0
OR5AN1 2489.0 -17208.0
OR5AP2 -3127.0 -11973.0
OR5AR1 -1874.0 -14269.0
OR5AS1 -13153.0 938.0
OR5AU1 2200.0 -5359.0
OR5B12 -146.0 -13825.0
OR5B17 -705.0 -17240.0
OR5B2 2720.0 1636.0
OR5B21 -1069.0 -15161.0
OR5B3 -6800.0 291.0
OR5C1 2017.0 109.0
OR5D13 -15159.0 -50.0
OR5D14 -16195.0 -11181.0
OR5D16 -10793.0 -7621.0
OR5D18 -16500.0 -9293.0
OR5H1 -3524.0 1179.0
OR5I1 -16368.0 -2601.0
OR5K2 -15030.0 -17159.0
OR5L1 -16220.0 -3085.0
OR5L2 -16386.0 -2556.0
OR5M1 2646.0 -17284.0
OR5M10 -1650.0 -2753.0
OR5M11 883.0 -1423.0
OR5M8 2505.0 413.0
OR5M9 -3553.0 -3848.0
OR5P2 -8117.0 1454.0
OR5P3 -378.0 -543.0
OR5T2 -4625.0 1151.0
OR5V1 -3651.0 -5398.0
OR6A2 -8564.0 -1796.0
OR6B1 1112.0 -7377.0
OR6B2 -6748.0 1755.0
OR6B3 1232.0 60.0
OR6C1 2129.0 -205.0
OR6C3 -2819.0 1583.0
OR6C4 2249.0 -7679.0
OR6C70 575.0 -10656.0
OR6C74 -9292.0 -9113.0
OR6F1 -13642.0 -3801.0
OR6K2 -1150.0 -14344.0
OR6K3 2202.0 1806.0
OR6K6 2237.0 -2185.0
OR6M1 1983.0 -7028.0
OR6N1 2667.0 -1963.0
OR6N2 828.0 493.0
OR6P1 579.0 -12031.0
OR6Q1 2116.0 1354.0
OR6S1 940.0 -3598.0
OR6T1 2401.0 -5465.0
OR6V1 1378.0 1480.0
OR6X1 2675.0 -10365.0
OR6Y1 1679.0 -8377.0
OR7A10 -9133.0 1801.0
OR7A17 -10382.0 813.0
OR7A5 1491.0 -11643.0
OR7C1 1848.0 1366.0
OR7C2 -2264.0 1254.0
OR7D2 2593.0 1325.0
OR7D4 -4058.0 695.0
OR7E24 -8241.0 1850.0
OR7G1 2520.0 1438.0
OR7G2 -12727.0 158.0
OR7G3 -2001.0 701.0
OR8A1 -16143.0 -4964.0
OR8B12 -7887.0 -15412.0
OR8B2 -561.0 -15151.0
OR8B3 2349.0 -16401.0
OR8B4 2402.0 -8112.0
OR8B8 453.0 899.0
OR8D1 2482.0 -11633.0
OR8D2 -4010.0 -13722.0
OR8D4 834.0 -11057.0
OR8G1 1214.0 -13130.0
OR8G5 -1607.0 -15856.0
OR8H1 2558.0 1899.0
OR8H2 -14383.0 1712.0
OR8H3 -16453.0 122.0
OR8I2 -15599.0 1925.0
OR8J3 -1634.0 -12853.0
OR8K5 -13054.0 -12073.0
OR8S1 -1573.0 -7705.0
OR8U3 1489.0 -17264.0
OR8U8 -4705.0 -2641.0
OR9A2 -4850.0 365.0
OR9A4 2325.0 -7360.0
OR9G1 -3502.5 -6630.5
OR9G4 145.0 -12582.0
OR9G9 -3502.5 -6630.5
OR9I1 2135.0 1869.0
OR9K2 -6936.0 -12740.0
OR9Q1 111.0 1050.0
OR9Q2 668.0 1733.0
OTOF -6169.0 -2349.0
OTOP1 -13972.0 -7077.0
PCDH15 196.0 -4636.0
PCLO -11533.0 -12090.0
PDE6A -4085.0 -1334.0
PDE6B -10425.0 -8967.0
PDE6G -374.0 -10685.0
PJVK -15785.0 -17136.0
PLB1 -1241.0 -1665.0
PLCB2 -7364.0 -811.0
PLS1 -11595.0 -14403.0
PNLIP 2081.0 1655.0
PRKCA -1.0 -3348.0
PRKCQ -2672.0 -1204.0
RAB3A -15038.0 -3037.0
RBP1 -3176.0 -10476.0
RBP2 -743.0 -5912.0
RBP3 -7261.0 556.0
RBP4 -7352.0 -16071.0
RCVRN 323.0 968.0
RDH10 -11083.0 -15575.0
RDH11 -11523.0 -11620.0
RDH12 2515.0 -171.0
RDH16 1632.0 1232.0
RDH5 -4201.0 -3786.0
RDH8 -15586.0 -2144.0
RDX -15250.0 -11673.0
REEP1 -7132.0 -14378.0
RETSAT 1030.0 -8071.0
RGS9 398.0 -7333.0
RGS9BP -13439.0 -15945.0
RHO -4126.0 137.0
RIPOR2 -6561.0 -3904.0
RLBP1 -4916.0 408.0
RPE65 1933.0 -9177.0
RTP1 -63.0 -2577.0
RTP2 220.0 -1142.0
SAG 1096.0 -4620.0
SCN1B -13974.0 -14167.0
SCN2A -14116.0 -7994.0
SCN2B 1300.0 -8531.0
SCN3A -9308.0 -5458.0
SCN4B -8931.0 -11715.0
SCN9A -3738.0 -11719.0
SCNN1A -8549.0 -444.0
SCNN1B -9763.0 -1019.0
SCNN1D -14335.0 -8059.0
SCNN1G -12280.0 -7880.0
SDC1 -14370.0 -9666.0
SDC2 -5455.0 -13416.0
SDC3 -14944.0 -13897.0
SDC4 -7190.0 -3608.0
SDR9C7 1155.0 -4155.0
SLC17A8 -6029.0 -16678.0
SLC24A1 1956.0 -2811.0
SLC26A5 -13502.0 -13252.0
SNAP25 -9473.0 -7724.0
SPTAN1 -14229.0 -9717.0
SPTBN1 280.0 -6570.0
STRA6 -14621.0 -3670.0
STRC 2327.0 1509.0
STX1A -14767.0 -5292.0
TAS1R1 -15720.0 -2816.0
TAS1R2 -3285.0 50.0
TAS1R3 -15891.0 -6493.0
TAS2R1 1280.0 -15436.0
TAS2R13 -16474.0 -2923.0
TAS2R16 2032.0 -12486.0
TAS2R20 -16141.0 1406.0
TAS2R3 2166.0 -12488.0
TAS2R31 -9857.0 -2801.0
TAS2R38 1477.0 -7007.0
TAS2R39 -6063.0 796.0
TAS2R4 2600.0 215.0
TAS2R40 2160.0 -1353.0
TAS2R41 -6461.0 -6605.0
TAS2R43 -16381.0 139.0
TAS2R5 2122.0 -10136.0
TAS2R50 -7608.0 -14294.0
TAS2R7 -14631.0 -8244.0
TMC1 1342.0 -6268.0
TMC2 -10128.0 -469.0
TMIE -12039.0 -14285.0
TPRN -16275.0 -16464.0
TRIOBP -11195.0 -14227.0
TRPM4 -7581.0 -1516.0
TRPM5 -14000.0 53.0
TTR 995.0 -4386.0
TWF1 -7670.0 -16215.0
TWF2 -16222.0 -4474.0
USH1C -9797.0 -7878.0
USH1G -3180.0 -15937.0
VAMP2 -15799.0 -11261.0
WHRN -7487.0 -1635.0
XIRP2 -3892.0 -11394.0



REACTOME_KERATINIZATION

REACTOME_KERATINIZATION
metric value
setSize 198
pMANOVA 3.18e-21
p.adjustMANOVA 1.74e-18
s.dist 0.449
s.Estill 0.316
s.Novakovic 0.318
p.Estill 1.6e-14
p.Novakovic 1.19e-14




Top 20 genes
Gene Estill Novakovic
SPRR2E 2708 1797
KRTAP4-9 2686 1761
KRTAP4-7 2653 1610
SPRR2G 2709 1526
KRTAP5-7 2099 1739
KRTAP19-4 2654 1322
SPRR2B 1675 1609
SPRR2D 1935 1345
KRTAP8-1 2615 882
LCE1A 1573 1446
KRTAP23-1 1674 1237
CASP14 2396 766
KRTAP5-1 812 1922
LCE2B 1713 904
KRTAP4-4 998 1517
LCE3D 2432 619
KRT25 1117 1032
PI3 547 1296
SPRR3 676 958
KRTAP4-8 316 1853

Click HERE to show all gene set members

All member genes
Estill Novakovic
CAPN1 -7033 -14567
CAPNS1 -8831 -7934
CASP14 2396 766
CDSN -7678 -2686
CELA2A 1198 -2527
CSTA -2236 1823
DSC1 2561 -10422
DSC2 -16340 -15466
DSC3 -14244 -16337
DSG1 -4627 -8279
DSG2 -10991 264
DSG3 -16377 -2322
DSP -9347 -11219
EVPL -6516 -1883
FLG -4195 908
FURIN -10334 -10318
IVL -746 -13412
JUP -8132 -2088
KAZN -4924 -4018
KLK12 -4356 39
KLK13 -4378 -10050
KLK14 -8357 232
KLK5 1372 -2329
KLK8 -9418 -1455
KRT1 1817 -3547
KRT10 -5351 -13637
KRT12 -2258 1525
KRT13 -5970 -3946
KRT14 -14882 847
KRT15 -13794 -6292
KRT16 -13124 -2267
KRT17 -12130 1210
KRT18 -15366 -8229
KRT19 -13618 -9580
KRT2 1518 -3197
KRT20 -1612 -841
KRT23 -3237 -2254
KRT24 -4681 -3540
KRT25 1117 1032
KRT26 -2139 -10372
KRT27 -470 -2770
KRT28 -2652 641
KRT3 -726 -7513
KRT31 85 -3925
KRT32 -11953 851
KRT33A -4894 -13087
KRT33B 1795 -8530
KRT34 -4854 -3996
KRT35 -3615 -6235
KRT36 -2413 760
KRT37 164 -6405
KRT38 1907 -3814
KRT39 2379 -6551
KRT4 -7475 -6614
KRT40 1316 -4981
KRT5 -2586 -131
KRT6A -789 1400
KRT6B -196 -3898
KRT6C -554 -1792
KRT7 -12475 -9283
KRT71 -11002 -804
KRT72 -9489 -4682
KRT73 -5884 -1913
KRT74 -13958 448
KRT75 -12519 1652
KRT76 -9108 -1825
KRT77 431 -9683
KRT78 -16173 -5378
KRT79 -9222 -6022
KRT8 -6155 -5219
KRT80 -13043 -3151
KRT81 -9609 74
KRT82 -9044 -533
KRT83 -14776 -1105
KRT84 -1564 -3879
KRT85 -8721 775
KRT86 -11530 -11977
KRT9 -12756 1355
KRTAP1-1 -2559 -17077
KRTAP1-3 1922 -7896
KRTAP1-5 1277 -149
KRTAP10-1 -6460 -616
KRTAP10-10 -10021 -10008
KRTAP10-11 -8654 -8563
KRTAP10-12 -4771 -10185
KRTAP10-2 -7369 -15391
KRTAP10-3 -2723 -9887
KRTAP10-4 1752 -10231
KRTAP10-5 -3304 871
KRTAP10-6 -16391 -2640
KRTAP10-7 -992 -6033
KRTAP10-8 2568 -1312
KRTAP10-9 1730 -12118
KRTAP11-1 1717 -7711
KRTAP12-1 325 -3112
KRTAP12-2 -2613 -16933
KRTAP12-3 -14852 355
KRTAP12-4 -11906 -7745
KRTAP13-1 1267 -6254
KRTAP13-2 -2184 1742
KRTAP13-3 2146 -4515
KRTAP13-4 -1452 -8978
KRTAP15-1 -839 -11374
KRTAP17-1 1081 -12681
KRTAP19-1 -14495 -1723
KRTAP19-2 901 -634
KRTAP19-3 -11663 -181
KRTAP19-4 2654 1322
KRTAP19-5 -14625 -2259
KRTAP19-7 2714 -8451
KRTAP19-8 2499 -13515
KRTAP2-1 -5304 -8757
KRTAP2-2 1463 -15886
KRTAP2-4 795 -13963
KRTAP20-1 -16290 -16845
KRTAP22-1 -14212 -6729
KRTAP23-1 1674 1237
KRTAP24-1 -93 -14622
KRTAP25-1 -1175 -545
KRTAP26-1 630 -16908
KRTAP27-1 1647 -16966
KRTAP3-1 1753 -14992
KRTAP3-2 2342 -8127
KRTAP3-3 -973 353
KRTAP4-1 -9139 -17236
KRTAP4-11 2525 -2980
KRTAP4-2 2490 -17042
KRTAP4-3 1621 -6832
KRTAP4-4 998 1517
KRTAP4-5 2582 -2576
KRTAP4-7 2653 1610
KRTAP4-8 316 1853
KRTAP4-9 2686 1761
KRTAP5-1 812 1922
KRTAP5-10 -4020 -122
KRTAP5-11 -5748 -523
KRTAP5-2 -13913 -11324
KRTAP5-3 -3379 459
KRTAP5-4 -3110 -2199
KRTAP5-5 -10028 -13189
KRTAP5-6 -1735 1607
KRTAP5-7 2099 1739
KRTAP5-8 842 -3519
KRTAP5-9 -14529 -13188
KRTAP6-1 -1538 1368
KRTAP6-2 161 986
KRTAP6-3 2031 -5477
KRTAP8-1 2615 882
KRTAP9-2 2671 -8057
KRTAP9-3 2365 -183
KRTAP9-4 -90 -11323
KRTAP9-8 -10070 -13679
KRTAP9-9 615 -5573
LCE1A 1573 1446
LCE1B 1038 -6328
LCE1C 1390 -1417
LCE1D 636 -1176
LCE1E -4730 1374
LCE1F -5456 1372
LCE2A 1265 -2384
LCE2B 1713 904
LCE2C -9805 -16162
LCE2D -10171 -1279
LCE3A -4875 1023
LCE3D 2432 619
LCE3E 641 -1317
LCE4A 2086 -18
LCE5A -6820 -3063
LCE6A 2381 -2116
LELP1 157 1478
LIPJ 1568 -425
LIPK 1207 -8439
LIPM 105 -12169
PCSK6 -516 -2478
PERP -5431 -16142
PI3 547 1296
PKP1 -6331 -6258
PKP2 -15110 -346
PKP3 -6359 -4582
PKP4 -3941 -6202
PPL -3523 -7230
PRSS8 -9013 -420
RPTN -895 -8692
SPINK5 -16373 -16126
SPINK9 2301 -8431
SPRR1A 1764 290
SPRR1B -1830 316
SPRR2A 1250 -4207
SPRR2B 1675 1609
SPRR2D 1935 1345
SPRR2E 2708 1797
SPRR2F -11348 -409
SPRR2G 2709 1526
SPRR3 676 958
ST14 -4421 510
TCHH -278 -3162
TGM1 -7665 819
TGM5 -894 -970



REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
metric value
setSize 1329
pMANOVA 1.64e-20
p.adjustMANOVA 6.75e-18
s.dist 0.172
s.Estill -0.0898
s.Novakovic -0.147
p.Estill 4.41e-08
p.Novakovic 3.25e-19




Top 20 genes
Gene Estill Novakovic
ZNF559 -15910 -17239
ZNF621 -16007 -17046
PRDX5 -15848 -17210
E2F1 -16127 -16773
CDKN2B -15666 -17173
LAMTOR2 -15827 -16936
RNU12 -16354 -16294
POLR2L -16149 -16420
PCGF5 -16121 -16394
KCTD6 -15793 -16502
H3C12 -15164 -17158
PIN1 -15899 -16296
ZNF92 -14893 -17224
VENTX -15063 -17017
MIR132 -14898 -17204
PAPOLA -16101 -15712
PRELID1 -16091 -15551
ATRIP -16346 -15271
ZNF770 -15998 -15457
CBX8 -15191 -16149

Click HERE to show all gene set members

All member genes
Estill Novakovic
ABL1 -712.0 -2410.0
ACTL6A -9017.0 -11605.0
ACTL6B -11050.0 -13185.0
AFF4 -6022.0 -15640.0
AGO1 -747.0 -11588.0
AGO2 -1851.0 -1680.0
AGO3 -13810.0 -14109.0
AGO4 -10031.0 -8287.0
AGRP -6753.0 772.0
AIFM2 -1434.0 -6809.0
AKT1 -6145.0 -2432.0
AKT2 -12142.0 -6370.0
AKT3 -835.0 -5588.0
ALYREF -15271.0 -5872.0
ANAPC1 -2324.0 -5744.0
ANAPC10 -11343.0 -5816.0
ANAPC11 -15553.0 -3569.0
ANAPC15 -5573.0 -1354.0
ANAPC16 -3464.0 -3219.0
ANAPC2 -8367.0 -1213.0
ANAPC4 -11051.0 -6188.0
ANAPC5 -7613.0 -11860.0
ANAPC7 -6389.0 -4274.0
APAF1 -11661.0 -14718.0
APOE -5441.0 -1114.0
ARID1A -9274.0 -13671.0
ARID1B -289.0 -3703.0
ARID2 -16038.0 -9622.0
ARID3A -2841.0 -2860.0
ARNT -12079.0 -1076.0
ARNT2 -4637.0 -9841.0
ASH2L -11017.0 -11523.0
ATAD2 -3107.0 -9541.0
ATF2 -6207.0 -6194.0
ATM -10666.0 -3054.0
ATR -5921.0 -15232.0
ATRIP -16346.0 -15271.0
ATXN3 -13152.0 -11284.0
AURKA -8302.0 -8099.0
AURKB -585.0 -2715.0
AUTS2 103.0 -7615.0
AXIN1 -2253.0 -3623.0
BANP 15.0 -1286.0
BARD1 -9780.0 -7224.0
BAX -8736.0 -14875.0
BBC3 -14007.0 -15395.0
BCL2L11 -10993.0 -13407.0
BCL2L14 1501.0 -4849.0
BCL6 -6524.0 -6685.0
BDNF -11228.0 -8010.0
BGLAP -7204.0 -11376.0
BID -887.0 -9305.0
BIRC5 -509.0 -2514.0
BLK -1113.0 -1693.0
BLM -8164.0 -12810.0
BMAL1 -6327.0 -3866.0
BMI1 -16012.0 -13112.0
BMP2 -12511.0 -11670.0
BNIP3L -4008.0 -14550.0
BRCA1 2021.0 628.0
BRD1 -3133.0 520.0
BRD2 -4858.0 -10910.0
BRD7 -14496.0 -2366.0
BRIP1 1640.0 -14117.0
BRPF1 -6074.0 -14826.0
BRPF3 -13944.0 -14464.0
BTG1 -14926.0 -14539.0
BTG2 -8814.0 -15838.0
CALM1 -11935.0 -10428.0
CAMK2A -10797.0 -6876.0
CAMK2B -10282.0 -6791.0
CAMK2D -2540.0 -11657.0
CAMK2G -2502.0 -899.0
CAMK4 -12072.0 -13319.0
CARM1 -7610.0 -7767.0
CASC3 -11669.0 -3656.0
CASP1 -2020.0 -1042.0
CASP10 -14260.0 27.0
CASP2 -5396.0 -5277.0
CASP6 -3593.0 -6777.0
CAT -11204.0 -1805.0
CAV1 -6955.0 -12026.0
CBFB -13871.0 -14941.0
CBX2 -14491.0 -6483.0
CBX3 -14373.0 -3696.0
CBX4 -7580.0 -13492.0
CBX5 -8663.0 -2470.0
CBX6 -11898.0 -11046.0
CBX8 -15191.0 -16149.0
CCN2 -6918.0 -16777.0
CCNA1 -11907.0 -12984.0
CCNA2 -6087.0 -16501.0
CCNB1 -15812.0 -8791.0
CCNC -514.0 -14769.0
CCND1 -3494.0 -11443.0
CCND2 -9651.0 -15597.0
CCND3 -13014.0 -8722.0
CCNE1 -14226.0 -16873.0
CCNE2 -10192.0 -8331.0
CCNG1 -5260.0 -15794.0
CCNG2 -1558.0 -10475.0
CCNH -7680.0 -16219.0
CCNK -13936.0 -16492.0
CCNT1 -3658.0 -12061.0
CCNT2 -1647.0 -12723.0
CDC16 -3120.0 -6337.0
CDC23 -4732.0 -5268.0
CDC25C -5672.0 -11011.0
CDC26 -5432.0 -868.0
CDC27 -8038.0 -11129.0
CDC40 -12577.0 -1236.0
CDC7 -9686.0 -12389.0
CDC73 -13398.0 -6655.0
CDK1 -629.5 -12551.0
CDK12 -524.0 -9290.0
CDK13 -10950.0 -10761.0
CDK2 -241.0 -10000.0
CDK4 -12590.0 -14349.0
CDK5 -4592.0 -13544.0
CDK5R1 -8850.0 -15041.0
CDK6 -7466.0 -5435.0
CDK7 -11455.0 -8357.0
CDK8 -5195.0 -12573.0
CDK9 -3604.0 -16780.0
CDKN1A -7625.0 -12022.0
CDKN1B -15950.0 -12998.0
CDKN2A -13143.0 -1475.0
CDKN2B -15666.0 -17173.0
CEBPB -15578.0 -14184.0
CENPJ -3229.0 -6985.0
CGA -16413.0 -6356.0
CGB3 -14053.0 1527.0
CGB5 -11747.0 1058.0
CGB8 -16068.0 1120.0
CHD3 -3938.0 -1979.0
CHD4 -7292.0 -147.0
CHEK1 -5590.0 -8025.0
CHEK2 -2471.0 -14997.0
CHTOP -9116.0 -7345.0
CITED2 -15475.0 -11600.0
CITED4 -12337.0 -16913.0
CLDN5 -16158.0 -10726.0
CLP1 -7232.0 -15909.0
CNOT1 -2675.0 -11079.0
CNOT10 -6752.0 -9350.0
CNOT11 -15385.0 -5798.0
CNOT2 -10339.0 -8189.0
CNOT3 -9810.0 -11936.0
CNOT4 -2717.0 -13848.0
CNOT6 -7806.0 -3349.0
CNOT6L -15106.0 -13797.0
CNOT7 -15517.0 -12237.0
CNOT8 -6864.0 -11786.0
CNOT9 -5316.0 -4616.0
COL1A1 -6605.0 -9851.0
COL1A2 -6107.0 -9390.0
COX11 -10902.0 -15866.0
COX14 -15402.0 -15339.0
COX16 -10443.0 134.0
COX18 -14154.0 -9252.0
COX19 -8594.0 -5715.0
COX20 -9445.0 -15182.0
COX4I1 -8427.0 -17276.0
COX5A -12320.0 -13007.0
COX5B -14297.0 -12160.0
COX6A1 -2855.0 -15071.0
COX6B1 -4301.0 -9406.0
COX6C -6273.0 -2535.0
COX7A2L -12857.0 -12460.0
COX7C -11305.0 -12041.0
COX8A 1645.0 -16534.0
CPSF1 -8024.0 -3809.0
CPSF2 -7994.0 -16679.0
CPSF3 -8471.0 -11192.0
CPSF4 -8835.0 -13204.0
CPSF6 -13603.0 -8622.0
CPSF7 -11225.0 -9073.0
CR1 -9172.0 -6776.0
CRADD 1102.0 -3697.0
CREB1 -16059.0 -6298.0
CREBBP 522.0 -5671.0
CRH -4680.0 -10501.0
CSF1R -947.0 -1320.0
CSF2 -6988.0 -975.0
CSNK2A1 -10932.0 -4915.0
CSNK2A2 -15748.0 -7535.0
CSNK2B -367.0 -14595.0
CSTF1 -7777.0 -11962.0
CSTF2T 263.0 -5797.0
CSTF3 -3210.0 -13824.0
CTDP1 -410.0 -6290.0
CTLA4 1388.0 -9679.0
CTNNB1 -16336.0 -12572.0
CTR9 792.0 -9473.0
CTSK 1481.0 -3271.0
CTSL -10007.0 -17179.0
CTSV -14681.0 -8617.0
CUL1 -2215.0 449.0
CYCS -13068.0 -11301.0
DAXX -5751.0 -1962.0
DDB2 -3131.0 -10737.0
DDIT3 -14204.0 -11300.0
DDIT4 -14788.0 -15720.0
DDX39A -7150.0 -11299.0
DEK -13825.0 -4695.0
DGCR8 -2002.0 -10436.0
DHX38 -1782.0 -11608.0
DLL1 -5546.0 -16369.0
DLX5 -3537.0 -6190.0
DLX6 -5633.0 -16290.0
DNA2 -3490.0 -12624.0
DPY30 1989.0 -4838.0
DYRK2 1332.0 -2076.0
E2F1 -16127.0 -16773.0
E2F4 -12111.0 -13562.0
E2F5 -13411.0 -7919.0
E2F6 -5691.0 -3256.0
E2F7 -7635.0 -11226.0
E2F8 -9471.0 -15301.0
EAF1 -10314.0 -2604.0
EAF2 -13691.0 474.0
EED -10652.0 -4813.0
EGFR -4785.0 -1340.0
EHMT1 708.0 -1487.0
EHMT2 -2283.0 -2489.0
EIF4A3 -30.0 -4961.0
ELF1 -3269.0 648.0
ELF2 -7113.0 -9856.0
ELL -7312.0 -5309.0
ELL2 -8643.0 -9720.0
ELL3 -6812.0 -16086.0
ELOA -12870.0 -15681.0
ELOA2 2395.0 71.0
ELOB -10647.0 -14069.0
ELOC -661.0 -10616.0
EP300 -1567.0 -10732.0
EPC1 -13079.0 -13282.0
ERBB2 -7765.0 -3322.0
ERCC2 -6567.0 -8284.0
ERCC3 -5594.0 1083.0
ESR1 -2348.0 -8296.0
ESR2 -11908.0 -10224.0
ESRRA -14411.0 -14645.0
ESRRB -2722.0 -5642.0
ESRRG -5944.0 -9488.0
EXO1 -10822.0 -13991.0
EZH2 -5256.0 -15114.0
FANCC -2517.0 -6822.0
FANCD2 -11197.0 -6831.0
FANCI -6292.0 -15584.0
FAS -10156.0 -3617.0
FASLG -962.0 -12725.0
FBXO32 -10663.0 -12770.0
FBXW7 -13298.0 -13607.0
FIP1L1 -12218.0 -16714.0
FKBP5 -6337.0 -8804.0
FOS -6751.0 -11648.0
FOXG1 -15141.0 -11721.0
FOXO1 -8262.0 -5143.0
FOXO3 -8508.0 -8657.0
FURIN -10334.0 -10318.0
FYTTD1 -15501.0 -6181.0
FZR1 -7455.0 -2900.0
G6PC1 566.0 -2983.0
GAD1 -2653.0 -16474.0
GAD2 -11599.0 -13368.0
GADD45A -15305.0 -14391.0
GAMT -15211.0 -10170.0
GATA2 -12931.0 -14969.0
GATA3 -11063.0 -12385.0
GATA4 -1245.0 -11734.0
GATAD2A -9795.0 -3375.0
GATAD2B -8455.0 -443.0
GCK -10888.0 -3992.0
GEM -3111.0 -14389.0
GLI2 -97.0 -496.0
GLI3 -2145.0 -8836.0
GLS -6798.0 -5184.0
GLS2 -9647.0 -1134.0
GP1BA -15483.0 1443.0
GPAM -10688.0 -12991.0
GPI -4859.0 -15098.0
GPRIN1 -13961.0 -11051.0
GPS2 -1744.0 -12885.0
GPX2 848.0 -12900.0
GRIA2 -8803.0 -11867.0
GRIN2A -5136.0 -4438.0
GRIN2B -572.0 -4443.0
GSK3B -13275.0 -5625.0
GSR 362.0 -15617.0
GTF2A1 -6836.0 -12317.0
GTF2A2 -1375.0 -14599.0
GTF2B 1347.0 530.0
GTF2E1 -3851.0 -5666.0
GTF2E2 -14763.0 -7061.0
GTF2F1 -4222.0 -13948.0
GTF2F2 -12677.0 -7911.0
GTF2H1 -6201.0 -14095.0
GTF2H3 -11360.0 -16525.0
GTF2H4 -2192.0 -10297.0
GTF2H5 -11128.0 -13219.0
H2AC14 -740.0 -6291.0
H2AC18 -10109.5 -16821.5
H2AC19 -10109.5 -16821.5
H2AC20 -9365.0 -421.0
H2AC4 -8682.0 -7652.0
H2AC6 -3772.0 -14402.0
H2AC7 -10309.0 -3529.5
H2AC8 -15265.0 -12472.0
H2AJ -360.0 -16792.0
H2AX -13329.0 -16764.0
H2AZ1 -10477.0 -10825.0
H2AZ2 -15177.0 -12968.0
H2BC1 930.5 1414.0
H2BC10 -12140.0 -5784.0
H2BC11 -4716.0 -15808.0
H2BC12 -3961.0 -14793.0
H2BC13 -11400.0 761.0
H2BC14 -1609.0 -8267.0
H2BC15 -2744.0 -168.0
H2BC17 -16322.0 -3166.0
H2BC21 -8996.0 -6316.0
H2BC26 -11379.0 -16861.0
H2BC3 -15205.0 -10594.0
H2BC4 -10641.0 -8955.0
H2BC5 -9533.0 315.0
H2BC6 -15206.0 266.0
H2BC7 -11776.0 -3529.5
H2BC8 -15228.0 -8541.0
H2BC9 -9951.5 -12902.5
H3-3A -13934.0 -14636.0
H3-3B -9143.0 -13971.0
H3C1 -9230.0 -14629.0
H3C10 -3065.0 -374.0
H3C11 -7068.0 -13728.0
H3C12 -15164.0 -17158.0
H3C13 -4294.0 -15204.0
H3C2 -15289.0 -11553.0
H3C3 -6133.0 -14272.0
H3C4 -9971.0 -5667.0
H3C6 371.0 -17250.0
H3C7 -9951.5 -12902.5
H3C8 -15918.0 -12729.0
H4C1 -14459.0 -9617.0
H4C11 854.0 -16001.0
H4C12 -2120.0 -5312.0
H4C13 -334.0 -15402.0
H4C16 -7238.0 -8548.0
H4C2 -7763.0 -2343.0
H4C3 -5978.0 -7968.0
H4C4 -850.0 -16161.0
H4C5 -1971.0 -1886.0
H4C6 -9232.0 -16384.0
H4C8 -3484.0 -14606.0
H4C9 -10105.0 -17149.0
HAND2 -14808.0 -14672.0
HDAC1 -9758.0 -7989.0
HDAC10 -11263.0 -12640.0
HDAC11 -1532.0 -15783.0
HDAC2 -13055.0 -10473.0
HDAC3 -13458.0 -14340.0
HDAC4 -3364.0 -2218.0
HDAC5 -8748.0 -2168.0
HDAC7 -6934.0 -1613.0
HDAC9 -376.0 -5011.0
HES1 -14797.0 -15775.0
HEY1 -11558.0 -17148.0
HEY2 -13474.0 -12753.0
HIPK1 -8670.0 -910.0
HIPK2 -1479.0 -2831.0
HIVEP3 -7348.0 -2278.0
HNF4A -4104.0 -2119.0
HNF4G 1375.0 -9267.0
HSPD1 -13321.5 -16379.0
HTT -3423.0 -2709.0
HUS1 -1463.0 -13599.0
ICE1 -14189.0 -14024.0
ICE2 -16258.0 -11122.0
IFNG -3372.0 -3993.0
IGFBP1 -10627.0 -13509.0
IGFBP3 -9231.0 -7195.0
IHH -14855.0 -8907.0
IL2RA -2198.0 -6447.0
IL3 -12745.0 1542.0
IL6 -14125.0 271.0
ING2 -15542.0 -14717.0
ING5 -3048.0 -5274.0
INS -12821.0 -8034.0
INTS1 -8140.0 -4878.0
INTS10 -4447.0 -13091.0
INTS11 -9105.0 -11524.0
INTS12 -12554.0 -3995.0
INTS13 -15830.5 -12402.0
INTS14 -9826.0 -10773.0
INTS2 1161.0 -7120.0
INTS3 -5601.0 -3501.0
INTS4 -5098.0 -2053.0
INTS5 -11226.0 -9507.0
INTS6 -15448.0 -15400.0
INTS7 -3081.0 -13176.0
INTS8 -3375.0 -8624.0
INTS9 -1144.0 -3974.0
IQSEC3 -6654.0 -4204.0
ITCH -4315.0 -7177.0
ITGA2B -12457.0 -10398.0
ITGA4 -15859.0 -12983.0
ITGA5 -8805.0 -1201.0
ITGAL -2798.0 712.0
ITGBL1 -3752.0 -2876.0
IWS1 -2778.0 -14804.0
JAG1 -8627.0 -13234.0
JMY -12186.0 -15223.0
JUN -12813.0 -12417.0
JUNB -14339.0 -17098.0
KAT2A -1001.0 -115.0
KAT2B -3115.0 -6975.0
KAT5 -7750.0 -6812.0
KAT6A -304.0 -8632.0
KCNIP3 -9066.0 -7017.0
KCTD1 -11924.0 -11171.0
KCTD15 -6272.0 -6320.0
KCTD6 -15793.0 -16502.0
KDM5B -11804.0 -11594.0
KIT -1921.0 -5382.0
KLF4 -10639.0 -16838.0
KMT2A -5298.0 -15746.0
KMT2C -8906.0 -7703.0
KMT2E -6606.0 -13323.0
KMT5A -9451.0 -10739.0
KRAS -9621.0 -16093.0
KRBA1 -3098.0 -6584.0
KRBOX5 -7540.0 -12326.0
L3MBTL1 -15421.0 -2863.0
L3MBTL2 -4047.0 -10490.0
LAMTOR1 -4373.0 -1485.0
LAMTOR2 -15827.0 -16936.0
LAMTOR3 -9742.0 -9546.0
LAMTOR4 -3862.0 -10879.0
LAMTOR5 -5629.0 -15481.0
LBR -14393.0 -367.0
LDB1 -7790.0 -15978.0
LEF1 -6372.0 -10649.0
LEO1 -10346.0 -10399.0
LGALS3 -14121.0 -5678.0
LIFR -1729.0 -11813.0
LMO1 -7789.0 -5092.0
LMO2 -4494.0 -2815.0
LRPPRC 1909.0 -6137.0
LSM10 -8842.0 -15206.0
LSM11 -3647.0 -16935.0
MAF -15687.0 -15112.0
MAGOH -2775.0 -16629.0
MAGOHB -7797.0 -17140.0
MAML1 -11280.0 -8795.0
MAML2 -337.0 -5532.0
MAML3 -2889.0 -6166.0
MAP2K6 -1705.0 -7317.0
MAPK1 -9762.0 -6238.0
MAPK11 -5152.0 -7765.0
MAPK14 -13326.0 -12144.0
MAPK3 -14286.0 -1298.0
MAPKAP1 1196.0 -6058.0
MAPKAPK5 -15076.0 -14461.0
MAX -6413.0 -8827.0
MBD3 -13231.0 -466.0
MDC1 -2592.0 -10245.0
MDM2 -10651.0 113.0
MDM4 -1979.0 -12057.0
MEAF6 -14719.0 -14680.0
MED1 352.0 -15119.0
MED10 -12783.0 539.0
MED13 -13051.0 -13042.0
MED15 -1580.0 -4574.0
MED16 -3213.0 -4323.0
MED17 -15855.0 -9583.0
MED20 -9137.0 -6886.0
MED23 -10058.0 -9909.0
MED24 -6466.0 -11256.0
MED25 -4071.0 -8797.0
MED26 -7343.0 -12052.0
MED27 -641.0 -3203.0
MED30 -13292.0 -11509.0
MED31 -1879.0 -14559.0
MED4 -12740.0 -15713.0
MED6 -11006.0 -13714.0
MED7 -7875.0 -972.0
MED8 -11757.0 -15373.0
MEF2C -3644.0 -5180.0
MEN1 -6989.0 -12382.0
MET -1987.0 -12834.0
MGA -10893.0 -5141.0
MIR132 -14898.0 -17204.0
MIR137 -15488.0 -4074.0
MIR24-1 1548.0 141.0
MIR24-2 -13601.0 -6025.0
MIR27A -11476.0 -12015.0
MLH1 -8071.0 -12183.0
MLLT1 -14818.0 -5598.0
MLLT3 -8288.0 -10633.0
MLST8 -15381.0 -13231.0
MMP13 -16276.0 -5701.0
MNAT1 -2305.0 547.0
MOBP 853.0 -9204.0
MOV10 -9064.0 -10123.0
MRE11 -5819.0 -3826.0
MSH2 -13421.0 -10832.0
MSX2 -6219.0 -10315.0
MTA2 -5187.0 -10678.0
MTOR 819.0 -8409.0
MYB -1618.0 -12227.0
MYBL2 -4276.0 -7558.0
MYC -9179.0 -13967.0
MYL9 -2392.0 -11517.0
NABP1 -13862.0 -15522.0
NABP2 -4967.0 -15531.0
NAMPT -7949.0 -15407.0
NBN -14657.0 -15359.0
NCBP1 -9559.5 -17039.0
NCBP2 -2050.0 -13946.0
NCOR1 -12162.0 -4890.0
NCOR2 -2181.0 -536.0
NDRG1 -3540.0 -6124.0
NDUFA4 -7632.0 -13255.0
NEDD4L -1262.0 -6491.0
NELFA -11067.0 -10631.0
NELFB -4375.0 -5089.0
NELFCD -14735.0 -10484.0
NELFE -2132.0 -7082.0
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ZNF213 -3413.0 -5049.0
ZNF214 -9155.0 -5193.0
ZNF215 -1614.0 -16987.0
ZNF221 2375.0 20.0
ZNF222 -480.0 -9079.0
ZNF223 1829.0 700.0
ZNF224 -3834.0 853.0
ZNF225 -9385.0 -3535.0
ZNF226 -5381.0 -724.0
ZNF227 910.0 -7845.0
ZNF23 -6166.0 -10131.0
ZNF230 779.0 -380.0
ZNF233 -544.0 -16963.0
ZNF234 -2171.0 -13617.0
ZNF235 -8284.0 -1994.0
ZNF248 -9102.0 -14475.0
ZNF25 -15641.0 -7242.0
ZNF250 -10778.0 -14532.0
ZNF253 -9207.0 -14824.0
ZNF254 -2881.0 494.0
ZNF256 -7557.0 -15047.0
ZNF257 -4723.0 -14819.0
ZNF26 -11703.0 -14093.0
ZNF263 -8777.0 -14350.0
ZNF264 -1426.0 -6346.0
ZNF266 -8716.0 -16995.0
ZNF267 634.0 -3957.0
ZNF268 -6258.0 -15908.0
ZNF273 -13521.0 -11900.0
ZNF274 -1335.0 -1936.0
ZNF28 -1191.0 -915.0
ZNF282 -4750.0 -2153.0
ZNF285 -5576.0 -13134.0
ZNF286A -5475.0 -3765.0
ZNF287 -7396.0 -12940.0
ZNF3 -5587.0 -11793.0
ZNF30 -6289.0 -15230.0
ZNF300 -16261.0 -4439.0
ZNF302 -15820.0 -11798.0
ZNF304 -6807.0 -12425.0
ZNF311 976.0 -2976.0
ZNF317 1631.0 -1009.0
ZNF320 946.0 1734.0
ZNF324 -8404.0 -9757.0
ZNF324B -8328.0 -14522.0
ZNF331 -1681.0 -1082.0
ZNF333 -5929.0 -10776.0
ZNF334 -9407.0 -16618.0
ZNF337 1020.0 -12369.0
ZNF33A -12282.0 -5859.0
ZNF33B -13637.0 -3784.0
ZNF34 -8208.0 -11450.0
ZNF343 -7486.0 -8873.0
ZNF347 -8782.0 -13468.0
ZNF350 -1180.0 -5822.0
ZNF354A -14988.0 -1535.0
ZNF354B -6995.0 -11838.0
ZNF354C -12555.0 -13977.0
ZNF37A -12423.0 -4031.0
ZNF382 -14593.0 -12029.0
ZNF383 -12347.0 1448.0
ZNF385A -10615.0 -5596.0
ZNF394 -14754.0 -7472.0
ZNF398 -10125.0 -5014.0
ZNF415 -1052.0 -1706.0
ZNF416 -10430.0 -17215.0
ZNF417 -6612.0 -9681.0
ZNF418 -12954.0 -13810.0
ZNF419 -5042.0 -10282.0
ZNF420 -14248.0 -2308.0
ZNF425 -8726.0 99.0
ZNF426 -2670.0 -13569.0
ZNF429 -10200.0 -16941.0
ZNF43 -6599.0 -14085.0
ZNF430 -1402.0 -16791.0
ZNF431 -11602.0 -7833.0
ZNF432 -12245.0 -8536.0
ZNF433 -4909.0 -8484.0
ZNF436 -8728.0 -13527.0
ZNF439 2112.0 519.0
ZNF440 -15128.0 -15101.0
ZNF441 -8776.0 -12612.0
ZNF442 -15572.0 -14198.0
ZNF443 -13108.0 -15038.0
ZNF445 349.0 -4307.0
ZNF446 1242.0 -13077.0
ZNF45 2234.0 -7562.0
ZNF454 -13023.0 -9836.0
ZNF460 -10180.0 -7202.0
ZNF461 -6829.0 -14108.0
ZNF468 -2545.0 -13020.0
ZNF470 -7780.0 -15789.0
ZNF471 -7940.0 1574.0
ZNF473 -13291.0 -10477.0
ZNF479 -883.0 541.0
ZNF480 -3869.0 -15054.0
ZNF483 -10873.0 -12053.0
ZNF484 -5537.0 -16661.0
ZNF485 -8710.0 -3029.0
ZNF486 -4376.0 -16085.0
ZNF490 -7084.0 -8091.0
ZNF492 -14801.0 -9363.0
ZNF493 367.0 -15349.0
ZNF496 -6306.0 -12888.0
ZNF500 -6973.0 -13760.0
ZNF506 -6677.0 1484.0
ZNF510 -2108.0 -11308.0
ZNF514 -5235.0 -13010.0
ZNF517 -1819.0 -3098.0
ZNF519 -3158.0 -9375.0
ZNF521 -8960.0 -12978.0
ZNF528 -11255.0 -16701.0
ZNF529 -13422.0 -16562.0
ZNF530 -6569.0 -11049.0
ZNF540 -4679.0 -10421.0
ZNF543 -12483.0 -8520.0
ZNF544 -16328.0 -7938.0
ZNF546 -15691.0 -12498.0
ZNF547 -13629.0 -3057.0
ZNF548 463.0 -15955.0
ZNF549 -10026.0 549.0
ZNF550 -3436.0 -1396.0
ZNF551 -11129.0 -7701.0
ZNF552 441.0 -12195.0
ZNF554 -15357.0 -3341.0
ZNF555 -12332.0 -15406.0
ZNF556 -4379.0 -3305.0
ZNF557 -4082.0 -7888.0
ZNF558 -1361.0 -8193.0
ZNF559 -15910.0 -17239.0
ZNF560 -7399.0 354.0
ZNF561 -1320.0 -6683.0
ZNF562 28.0 -14777.0
ZNF563 -12385.0 -17262.0
ZNF564 -1545.0 -15091.0
ZNF565 -3541.0 -10094.0
ZNF566 -4584.0 -16587.0
ZNF567 2723.0 -15076.0
ZNF568 -4045.0 -7633.0
ZNF569 -6108.0 -1421.0
ZNF570 -12271.0 -6006.0
ZNF571 -4000.0 -12424.0
ZNF573 18.0 -12707.0
ZNF577 -15335.0 -7374.0
ZNF582 -14789.0 -7176.0
ZNF583 -14838.0 -16527.0
ZNF584 -9819.0 -14563.0
ZNF585A 2115.0 -17047.0
ZNF585B 2330.0 -13774.0
ZNF586 -12319.0 -16581.0
ZNF587 1771.0 -9523.0
ZNF589 -10563.0 -3161.0
ZNF595 -16429.0 -3556.0
ZNF596 -4464.0 -2230.0
ZNF597 -11567.0 683.0
ZNF599 -6586.0 -14396.0
ZNF600 -12489.0 88.0
ZNF605 -3608.0 -1500.0
ZNF606 -1998.0 -7851.0
ZNF607 -570.0 12.0
ZNF610 -968.0 865.0
ZNF611 -5287.0 -1282.0
ZNF613 93.0 -2523.0
ZNF614 -12394.0 -16871.0
ZNF615 -1198.0 -16199.0
ZNF616 -3023.0 -4121.0
ZNF619 -5595.0 -8847.0
ZNF620 -5971.0 -4190.0
ZNF621 -16007.0 -17046.0
ZNF624 -14160.0 -14471.0
ZNF625 -10799.0 -13487.0
ZNF626 -8115.0 -11554.0
ZNF627 -1253.0 -13221.0
ZNF641 -2550.0 -16934.0
ZNF649 53.0 -15510.0
ZNF655 -9089.0 -12403.0
ZNF658 -16424.0 -3938.0
ZNF660 -1542.0 -11803.0
ZNF662 -2512.0 -1403.0
ZNF664 -9722.0 -13687.0
ZNF665 -9174.0 -7707.0
ZNF667 -15877.0 -10768.0
ZNF668 -4538.0 -5431.0
ZNF669 -3534.0 -3727.0
ZNF670 -5524.0 -14045.0
ZNF671 95.0 -16879.0
ZNF675 -7836.0 -7840.0
ZNF676 -13201.0 -10876.0
ZNF677 -291.0 -10317.0
ZNF678 -3846.0 -12730.0
ZNF679 271.0 1851.0
ZNF680 2433.0 -12070.0
ZNF681 -7410.0 -12880.0
ZNF682 -13020.0 -8816.0
ZNF684 -2814.0 -4285.0
ZNF688 -4845.0 -16288.0
ZNF689 1310.0 -4011.0
ZNF691 -3454.0 -13571.0
ZNF692 -7527.0 -12361.0
ZNF696 -14390.0 -4109.0
ZNF697 -10174.0 -817.0
ZNF699 2225.0 -7713.0
ZNF70 -10547.0 -15126.0
ZNF700 -5495.0 -13870.0
ZNF701 -3174.0 -16928.0
ZNF703 -14693.0 -14706.0
ZNF704 -4844.0 -4115.0
ZNF705A -696.0 1442.0
ZNF705D -7564.0 1759.0
ZNF706 -15769.0 -13438.0
ZNF707 -6958.0 -6171.0
ZNF708 -7876.0 -16942.0
ZNF709 -10167.0 -13398.0
ZNF71 -5356.0 -8248.0
ZNF710 -9435.0 -6945.0
ZNF713 2494.0 -2127.0
ZNF714 -1495.0 -4216.0
ZNF716 -2170.0 1745.0
ZNF717 -13284.0 -2583.0
ZNF718 -13636.0 -5182.0
ZNF721 -8039.0 -10194.0
ZNF727 -14949.0 -12330.0
ZNF732 2498.0 1747.0
ZNF735 1037.0 1380.0
ZNF737 -9634.0 -12475.0
ZNF738 -9528.0 -16974.0
ZNF74 -4069.0 -14003.0
ZNF740 -14350.0 -14547.0
ZNF746 386.0 -10586.0
ZNF747 -15387.0 -13437.0
ZNF749 -2158.0 -14808.0
ZNF750 912.0 516.0
ZNF75A -13669.0 -7984.0
ZNF761 -11218.0 688.0
ZNF764 -6580.0 -15823.0
ZNF77 692.0 -3619.0
ZNF770 -15998.0 -15457.0
ZNF771 -14826.0 -14500.0
ZNF772 -8970.0 468.0
ZNF773 -4620.0 -7699.0
ZNF774 -4549.0 -11592.0
ZNF775 -2217.0 -15146.0
ZNF776 -2012.0 -4179.0
ZNF777 -5405.0 -11726.0
ZNF778 -10217.0 -9967.0
ZNF782 1577.0 -12115.0
ZNF785 600.0 -8741.0
ZNF786 -14741.0 -4651.0
ZNF79 1034.0 -12619.0
ZNF790 -4938.0 -7144.0
ZNF791 -5272.0 -14281.0
ZNF792 -10261.0 -7473.0
ZNF793 -7437.0 -1850.0
ZNF799 -9314.0 -9367.0
ZNF804B -11498.0 -3331.0
ZNF839 -7095.0 -11210.0
ZNF860 -11736.0 -16703.0
ZNF875 -4453.0 -2655.0
ZNF92 -14893.0 -17224.0
ZNF99 -16466.0 -7090.0
ZSCAN25 -11653.0 -11437.0
ZSCAN32 -8223.0 -12758.0



REACTOME_TRANSLATION

REACTOME_TRANSLATION
metric value
setSize 280
pMANOVA 2.04e-19
p.adjustMANOVA 6.71e-17
s.dist 0.323
s.Estill -0.0469
s.Novakovic -0.32
p.Estill 0.177
p.Novakovic 3.04e-20




Top 20 genes
Gene Estill Novakovic
MRPL17 -16116 -17121
TRMT112 -15892 -17246
MRPL40 -16338 -16665
RPL36 -15878 -16971
AURKAIP1 -15638 -16852
SPCS1 -14955 -17272
MRPS26 -14964 -17073
MRPL42 -15800 -16106
MRPL55 -14809 -16520
RPS5 -15070 -15693
MTIF3 -15953 -14799
MRPL57 -15821 -14549
SRPRA -14147 -16039
EIF5B -13626 -16623
RPS21 -14247 -15846
MRPL38 -13455 -16751
SPCS3 -14774 -15170
EIF4EBP1 -13621 -16412
RPL13 -13096 -17048
FARSB -16147 -13763

Click HERE to show all gene set members

All member genes
Estill Novakovic
AARS1 -8527.0 -1108.0
AARS2 -8854.0 -8601.0
AIMP1 -8807.0 -8122.0
AIMP2 -6060.0 -13537.0
APEH -12695.0 -9399.0
AURKAIP1 -15638.0 -16852.0
CARS1 -5100.0 -725.0
CARS2 -1466.0 -2667.0
CHCHD1 -12312.0 -17184.0
DAP3 -4635.0 -238.0
DARS1 -7042.0 -16447.0
DARS2 -3316.0 -15164.0
DDOST -854.0 -14456.0
EARS2 -9983.0 -8205.0
EEF1A1 -7263.0 -14577.0
EEF1A2 -12865.0 -15926.0
EEF1B2 -8133.0 -12805.0
EEF1D -8984.0 -15865.0
EEF1E1 959.0 -11757.0
EEF1G 2157.0 -13285.0
EEF2 -12638.0 -4822.0
EIF2B1 -12481.0 -16725.0
EIF2B2 -14471.0 -12953.0
EIF2B3 -831.0 -8989.0
EIF2B4 -11102.0 -16666.0
EIF2B5 -11847.0 -6146.0
EIF2S1 -1610.0 -12288.0
EIF2S2 -9285.0 -8900.0
EIF3A -9723.0 -7339.0
EIF3B -3646.0 -3048.0
EIF3C 2672.5 -6604.0
EIF3D -9854.0 -12849.0
EIF3E 574.0 -9592.0
EIF3F -448.0 -5545.0
EIF3G -4857.0 -9751.0
EIF3H -5914.0 -7681.0
EIF3I -235.0 -12308.0
EIF3J -3349.0 -16580.0
EIF3K -13263.0 -15469.0
EIF3L -161.0 -14670.0
EIF3M -14583.0 -13861.0
EIF4A1 -4154.0 -1889.0
EIF4A2 -10801.0 -7915.0
EIF4B 1032.0 -5826.0
EIF4E -5903.0 -11598.0
EIF4EBP1 -13621.0 -16412.0
EIF4G1 -1656.0 -6170.0
EIF4H -8020.0 -13218.0
EIF5 -1328.0 -15948.0
EIF5B -13626.0 -16623.0
EPRS1 -11941.0 -6090.0
ERAL1 782.0 -9714.0
ETF1 -9521.0 -10565.0
FARS2 -3420.0 -4524.0
FARSA -5989.0 -3566.0
FARSB -16147.0 -13763.0
FAU -8361.0 -15762.0
GADD45GIP1 -9874.0 -1382.0
GARS1 -4544.0 -14963.0
GFM1 -9555.0 -13224.0
GFM2 -12136.0 -16596.0
GSPT1 -12163.0 -2538.0
HARS1 -10452.0 -13151.0
HARS2 -8810.0 -15586.0
IARS1 -14747.0 -11562.0
IARS2 -6381.0 -14738.0
KARS1 -5756.0 -15508.0
LARS1 -1448.0 -14052.0
LARS2 -6903.0 -9154.0
MARS1 -6439.0 -6949.0
MARS2 -10127.0 -14071.0
MRPL1 -2367.0 -4644.0
MRPL10 -7197.0 -12644.0
MRPL11 125.0 -1062.0
MRPL12 -11895.0 -14993.0
MRPL13 1660.0 -13367.0
MRPL14 -11843.0 -8304.0
MRPL15 -7349.0 -10727.0
MRPL16 -1917.0 894.0
MRPL17 -16116.0 -17121.0
MRPL18 -4819.0 -14508.0
MRPL19 -12430.0 -15859.0
MRPL2 -212.0 -705.0
MRPL20 -9523.0 -12591.0
MRPL21 -7755.0 -11862.0
MRPL22 -870.0 -11857.0
MRPL23 -11517.0 -10457.0
MRPL24 811.0 -13987.0
MRPL27 -7791.0 -10842.0
MRPL28 -12659.0 -5135.0
MRPL3 -6387.0 -13830.0
MRPL30 -7793.0 -11475.0
MRPL32 -10183.0 -15657.0
MRPL33 -10421.0 -4205.0
MRPL34 -15620.0 -11069.0
MRPL35 2189.0 -4760.0
MRPL36 -13742.0 -14953.0
MRPL37 -12016.0 -9872.0
MRPL38 -13455.0 -16751.0
MRPL39 -5542.0 -8518.0
MRPL4 -8036.0 -8427.0
MRPL40 -16338.0 -16665.0
MRPL41 -10344.0 -16980.0
MRPL42 -15800.0 -16106.0
MRPL43 -12670.0 -7226.0
MRPL44 -11032.0 -16378.0
MRPL45 833.0 102.0
MRPL46 -15794.0 -7820.0
MRPL47 -1153.0 -15015.0
MRPL48 786.0 -16397.0
MRPL49 -7465.0 -15622.0
MRPL50 -4013.0 -1457.0
MRPL51 -4931.0 -10319.0
MRPL52 -8844.0 -10845.0
MRPL53 -2699.0 -16266.0
MRPL54 -1078.0 -8366.0
MRPL55 -14809.0 -16520.0
MRPL57 -15821.0 -14549.0
MRPL58 -6773.0 -15593.0
MRPL9 -733.0 -6246.0
MRPS10 -5686.0 -6312.0
MRPS11 -16088.0 -9726.0
MRPS12 -4001.0 -14068.0
MRPS14 -1138.0 -9047.0
MRPS15 -2994.0 -16260.0
MRPS16 -7012.0 -13658.0
MRPS17 -5138.0 -7091.0
MRPS18A -1802.0 -6739.0
MRPS18B -3147.0 -8543.0
MRPS18C -11737.0 -2061.0
MRPS2 -2222.0 -14643.0
MRPS21 -9929.0 -2756.0
MRPS22 -3049.0 -8271.0
MRPS23 -8408.0 -15099.0
MRPS24 -9942.0 -12429.0
MRPS25 -11286.0 -14377.0
MRPS26 -14964.0 -17073.0
MRPS27 -4134.0 -11535.0
MRPS28 -8812.0 -8703.0
MRPS30 -251.0 -13585.0
MRPS31 -14696.0 -10357.0
MRPS33 -10752.0 -2795.0
MRPS34 -12970.0 -16982.0
MRPS35 -10186.0 -7152.0
MRPS5 -2094.0 -8961.0
MRPS6 -10130.0 -2730.0
MRPS7 552.0 -12911.0
MRPS9 -6686.0 -14761.0
MRRF -874.0 -11519.0
MTFMT -9209.0 -16939.0
MTIF2 -14408.0 -7565.0
MTIF3 -15953.0 -14799.0
MTRF1L -7918.0 -9437.0
N6AMT1 378.0 -11140.0
NARS1 -3675.0 -16374.0
NARS2 947.0 -1868.0
OXA1L 1460.0 -16371.0
PABPC1 -6557.0 -12965.0
PARS2 -3838.0 -6548.0
PPA1 -16148.0 -13704.0
PPA2 -11686.0 -13997.0
PTCD3 -5414.0 -10965.0
RARS1 -11216.0 -15911.0
RARS2 -10743.0 -12945.0
RPL10A -4327.0 -16688.0
RPL10L -4672.0 1242.0
RPL11 -7730.0 -11362.0
RPL12 -1818.0 -7657.0
RPL13 -13096.0 -17048.0
RPL13A -1938.5 -10955.5
RPL14 -8334.0 -15519.0
RPL15 -13598.0 -15972.0
RPL17 -4720.0 -15113.0
RPL18 -6084.0 -16405.0
RPL18A -13854.0 -12314.0
RPL19 -9925.0 -950.0
RPL21 -9899.5 -13500.5
RPL22 -2661.0 -13474.0
RPL22L1 -2679.0 -16975.0
RPL23 -3278.0 -4599.0
RPL23A -8489.0 -13877.0
RPL24 813.0 329.0
RPL26 -7851.0 -14206.0
RPL26L1 -4159.0 -17223.0
RPL27 -10972.0 -14660.0
RPL27A -11040.0 -16640.0
RPL28 -7060.0 -12491.0
RPL29 -6766.0 -14551.0
RPL3 -4433.0 -6744.0
RPL30 -3473.0 -13276.0
RPL31 160.0 -9807.0
RPL32 -8290.0 -7245.0
RPL34 -3639.0 913.0
RPL35 -12031.0 -16424.0
RPL35A -563.0 -483.0
RPL36 -15878.0 -16971.0
RPL36AL -12581.0 -15545.0
RPL37 -5636.0 -11980.0
RPL37A -8914.0 -12749.0
RPL38 -3414.0 -3066.0
RPL39L -2329.0 -16531.0
RPL3L -13013.0 328.0
RPL4 -7696.0 199.0
RPL41 -8377.0 -15742.0
RPL5 1478.0 -13656.0
RPL6 718.0 -2953.0
RPL7 -11616.0 -15741.0
RPL7A -11184.0 -3709.0
RPL8 -16023.0 -13701.0
RPL9 -4066.0 -291.0
RPLP0 -7445.0 -14511.0
RPLP1 -5049.0 -3663.0
RPLP2 -14824.0 -14743.0
RPN1 -12573.0 -5768.0
RPN2 -7951.0 -10026.0
RPS10 -11363.0 -14602.0
RPS11 -12666.0 -8009.0
RPS12 -5554.0 -5380.0
RPS13 541.0 -12870.0
RPS14 -14985.0 -576.0
RPS15 -11816.0 -15841.0
RPS15A 1563.0 -10896.0
RPS16 -12775.0 -13973.0
RPS17 363.0 -17286.0
RPS18 -5492.0 -6509.0
RPS19 -4848.0 -463.0
RPS2 -8403.0 -13161.0
RPS20 -9963.0 -9064.0
RPS21 -14247.0 -15846.0
RPS23 -4455.0 -10331.0
RPS24 1255.0 -3232.0
RPS25 -2544.0 -11699.0
RPS26 802.0 -7841.0
RPS27 1722.0 -11381.0
RPS27A -11481.0 -2147.0
RPS27L -9482.0 -16569.0
RPS28 -12352.0 -15277.0
RPS29 -8298.0 -16523.0
RPS3 1404.0 -10369.0
RPS3A -10279.0 -15494.0
RPS5 -15070.0 -15693.0
RPS6 -16407.0 -6799.0
RPS7 -3124.0 -12481.0
RPS8 -9073.0 -1281.0
RPS9 -11982.0 -623.0
RPSA -4693.0 -3295.0
SARS2 -5789.0 -12336.0
SEC11A -1941.0 -6232.0
SEC11C -9696.0 -11047.0
SEC61A1 -10621.0 -9787.0
SEC61A2 -11293.0 -10614.0
SEC61B -5808.5 -12331.0
SEC61G -12912.0 -16179.0
SPCS1 -14955.0 -17272.0
SPCS2 -7032.0 -14568.0
SPCS3 -14774.0 -15170.0
SRP14 -7444.0 -15842.0
SRP19 -907.0 -9199.0
SRP54 -6504.0 -7726.0
SRP68 -4242.0 -7502.0
SRP72 -10208.0 -14962.0
SRP9 -12584.0 -17181.0
SRPRA -14147.0 -16039.0
SRPRB -5891.0 -15710.0
SSR1 -4792.0 -8523.0
SSR2 -8494.0 -7855.0
SSR3 -9411.0 -4431.0
TARS1 -551.0 -13881.0
TARS2 -441.0 -2152.0
TRAM1 -12075.0 -14415.0
TRMT112 -15892.0 -17246.0
TSFM -471.0 -5035.0
TUFM -10548.0 -4900.0
UBA52 -10894.0 -4996.0
VARS1 -7001.0 -3364.0
VARS2 -6618.0 -11878.0
WARS1 -6673.0 -13094.0
WARS2 -2963.0 -14779.0
YARS1 -11492.0 -10376.0
YARS2 -6548.0 -13980.0



REACTOME_METABOLISM_OF_RNA

REACTOME_METABOLISM_OF_RNA
metric value
setSize 673
pMANOVA 6.18e-18
p.adjustMANOVA 1.69e-15
s.dist 0.21
s.Estill -0.0603
s.Novakovic -0.201
p.Estill 0.00774
p.Novakovic 5.92e-19




Top 20 genes
Gene Estill Novakovic
TRMT112 -15892 -17246
RPL36 -15878 -16971
POLR2L -16149 -16420
NUP37 -15153 -17285
PNRC2 -15485 -16726
NUP153 -14779 -17257
PAPOLA -16101 -15712
TSEN54 -16030 -15578
SNRNP40 -15294 -16098
PSMA7 -15238 -16097
SRSF2 -14070 -17242
PSMD1 -15755 -15264
PPP2CA -16303 -14663
DDX5 -15844 -14976
NIP7 -15328 -15460
RPS5 -15070 -15693
LSM7 -16128 -14627
WBP4 -15009 -15570
SF3B2 -14806 -15750
HNRNPU -15860 -14375

Click HERE to show all gene set members

All member genes
Estill Novakovic
A1CF -8664.0 -7935.0
AAAS -5233.0 -3868.0
ACIN1 -2538.0 -4457.0
ADAR -8586.0 -7210.0
ADARB1 -1887.0 -2738.0
ADAT1 -3714.0 -9673.0
ADAT2 -12708.0 -10546.0
ADAT3 -10691.0 -11921.0
AKT1 -6145.0 -2432.0
ALKBH8 -1583.0 -3149.0
ALYREF -15271.0 -5872.0
ANP32A -5874.0 -13384.0
APOBEC1 2131.0 -974.0
APOBEC2 -595.0 -5154.0
APOBEC3A -1556.0 841.0
APOBEC3B -7854.0 507.0
APOBEC3C 129.0 -1977.0
APOBEC3H 961.0 445.0
APOBEC4 -3307.0 -2008.0
AQR -4043.0 -16020.0
BCAS2 405.0 -12934.0
BMS1 -8114.0 -1830.0
BOP1 -12104.0 -7587.0
BUD13 -15395.0 -9266.0
BUD23 -15422.0 -10745.0
BUD31 -4516.0 -10144.0
BYSL -10901.0 -7824.0
C1D -2204.0 -8106.0
C2orf49 -13880.0 -6015.0
C9orf78 -6006.0 -11431.0
CACTIN -10497.0 -9393.0
CASC3 -11669.0 -3656.0
CCAR1 -5972.0 -14379.0
CCDC12 -8499.0 -1155.0
CCNH -7680.0 -16219.0
CDC40 -12577.0 -1236.0
CDC5L -6296.0 -10615.0
CDK7 -11455.0 -8357.0
CDKAL1 -951.0 -6811.0
CHERP -4639.0 -4769.0
CHTOP -9116.0 -7345.0
CLNS1A -14849.0 -7613.0
CLP1 -7232.0 -15909.0
CNOT1 -2675.0 -11079.0
CNOT10 -6752.0 -9350.0
CNOT11 -15385.0 -5798.0
CNOT2 -10339.0 -8189.0
CNOT3 -9810.0 -11936.0
CNOT4 -2717.0 -13848.0
CNOT6 -7806.0 -3349.0
CNOT6L -15106.0 -13797.0
CNOT7 -15517.0 -12237.0
CNOT8 -6864.0 -11786.0
CNOT9 -5316.0 -4616.0
CPSF1 -8024.0 -3809.0
CPSF2 -7994.0 -16679.0
CPSF3 -8471.0 -11192.0
CPSF4 -8835.0 -13204.0
CPSF6 -13603.0 -8622.0
CPSF7 -11225.0 -9073.0
CRNKL1 -5466.0 -13032.0
CSNK1D -10315.0 -2827.0
CSNK1E -12689.0 -11824.0
CSTF1 -7777.0 -11962.0
CSTF2T 263.0 -5797.0
CSTF3 -3210.0 -13824.0
CTNNBL1 -6158.0 -6087.0
CTU1 198.0 -9477.0
CTU2 -14574.0 -13184.0
CWC15 -13073.0 -16127.0
CWC22 -6853.0 -4559.0
CWC25 665.0 -14942.0
CWC27 -12578.0 -6208.0
CWF19L2 2306.0 -111.0
DCAF13 -9156.0 -5558.0
DCP1A -10322.0 -15177.0
DCP1B -114.0 -5956.0
DCP2 -4550.0 -6209.0
DCPS -5807.0 -3298.0
DDX1 -7482.0 -12132.0
DDX20 -7485.0 -16997.0
DDX21 -8139.0 -12017.0
DDX23 -5337.0 -3147.0
DDX39A -7150.0 -11299.0
DDX41 -14171.0 -11789.0
DDX42 -10272.0 -11282.0
DDX46 -11639.0 -15837.0
DDX47 -1790.0 -2387.0
DDX49 -4600.0 -8430.0
DDX5 -15844.0 -14976.0
DDX52 -8138.0 -12957.0
DDX6 -11477.0 -10749.0
DHX15 -1546.0 -14553.0
DHX16 -3294.0 -13216.0
DHX35 -744.0 -6980.0
DHX37 -2150.0 -5285.0
DHX38 -1782.0 -11608.0
DHX8 -6184.0 -6823.0
DHX9 -5995.0 -12772.0
DIMT1 -1868.0 -12883.0
DIS3 -2692.0 -3659.0
DNAJC8 -8792.0 -4162.0
DUS2 -13968.0 -10900.0
EBNA1BP2 -3522.0 -3267.0
EDC3 -3748.0 -6971.0
EDC4 -12424.0 -10167.0
EFTUD2 -2765.0 -9981.0
EIF4A1 -4154.0 -1889.0
EIF4A2 -10801.0 -7915.0
EIF4A3 -30.0 -4961.0
EIF4B 1032.0 -5826.0
EIF4E -5903.0 -11598.0
EIF4G1 -1656.0 -6170.0
ELAC2 -14476.0 -11266.0
ELAVL1 -10188.0 -6198.0
EMG1 -1928.0 -10969.0
EPRS1 -11941.0 -6090.0
ERCC2 -6567.0 -8284.0
ERCC3 -5594.0 1083.0
ERI1 -8397.0 -8222.0
ETF1 -9521.0 -10565.0
EXOSC1 -11535.0 -12332.0
EXOSC10 -11735.0 -4107.0
EXOSC2 -8230.0 -8207.0
EXOSC3 -3581.0 -16081.0
EXOSC4 -6412.0 -13941.0
EXOSC5 -14082.0 -9766.0
EXOSC6 -12471.0 -16303.0
EXOSC7 -9065.0 -6973.0
EXOSC8 -11683.0 -3776.0
EXOSC9 -8456.0 -7477.0
FAM32A -727.0 -16918.0
FAM98B -4564.0 -12340.0
FAU -8361.0 -15762.0
FBL -10466.0 -1981.0
FCF1 -1801.0 -6814.0
FIP1L1 -12218.0 -16714.0
FTSJ3 -9643.0 -12079.0
FUS -11629.0 -1252.0
FYTTD1 -15501.0 -6181.0
GAR1 -10289.0 -10526.0
GCFC2 -14194.0 -3455.0
GEMIN4 -15080.0 -231.0
GEMIN5 -7199.0 -15040.0
GEMIN6 -10776.0 -4730.0
GEMIN7 -3682.0 -906.0
GLE1 -3232.0 -7220.0
GNL3 -569.0 -6917.0
GPATCH1 -3252.0 -8844.0
GSPT1 -12163.0 -2538.0
GTF2F1 -4222.0 -13948.0
GTF2F2 -12677.0 -7911.0
GTF2H1 -6201.0 -14095.0
GTF2H3 -11360.0 -16525.0
GTF2H4 -2192.0 -10297.0
GTF2H5 -11128.0 -13219.0
GTPBP3 -8194.0 -9328.0
HBS1L -12739.0 -6102.0
HEATR1 -6450.0 -6818.0
HNRNPA1 -12252.0 -3722.0
HNRNPA2B1 -12846.0 -7400.0
HNRNPA3 -15150.0 -8362.0
HNRNPC -104.0 -6537.0
HNRNPD -9956.0 -3603.0
HNRNPF -11041.0 -15543.0
HNRNPH1 -6112.0 -10775.0
HNRNPK -12474.0 -14011.0
HNRNPL -2988.0 -17102.0
HNRNPM -7476.0 -3723.0
HNRNPR -14445.0 -11260.0
HNRNPU -15860.0 -14375.0
HSPA1A -11140.0 -12542.0
HSPA8 -7258.0 -2055.0
HSPB1 -15704.0 -9010.0
IGF2BP1 -4618.0 -9136.0
IGF2BP2 -4815.0 -1980.0
IGF2BP3 -4784.0 -9114.0
IK 60.0 -1920.0
IMP3 -9739.0 -14626.0
IMP4 -488.0 -3520.0
ISG20L2 -5205.0 -10925.0
ISY1 -7147.0 -13859.0
KHSRP -5753.0 705.0
KRR1 2095.0 -6080.0
LCMT2 -16031.0 -13995.0
LENG1 -8666.0 -15914.0
LSM1 -12657.0 -13975.0
LSM10 -8842.0 -15206.0
LSM11 -3647.0 -16935.0
LSM2 -3415.0 -4363.0
LSM3 -13185.0 -15226.0
LSM4 -12297.0 -5563.0
LSM5 -6024.0 -13581.0
LSM6 -6815.0 -9061.0
LSM7 -16128.0 -14627.0
LTV1 -9691.0 -6220.0
LUC7L3 -10116.0 -14390.0
MAGOH -2775.0 -16629.0
MAGOHB -7797.0 -17140.0
MAPK11 -5152.0 -7765.0
MAPK14 -13326.0 -12144.0
MAPKAPK2 -4999.0 -998.0
METTL1 -3382.0 -11518.0
METTL14 -7855.0 -15504.0
METTL3 -1285.0 -10627.0
MFAP1 2101.0 -7421.0
MNAT1 -2305.0 547.0
MPHOSPH10 -11654.0 -13392.0
MPHOSPH6 -12110.0 -16004.0
MRM1 -2362.0 -7108.0
MRM2 -4752.0 -14753.0
MRM3 -9327.0 -10610.0
MTERF4 -3698.0 -12190.0
MTO1 -4341.0 -10140.0
MTREX -15180.0 -11259.0
NAT10 -2065.0 -662.0
NCBP1 -9559.5 -17039.0
NCBP2 -2050.0 -13946.0
NCL -1119.0 -11387.0
NDC1 -11478.0 -8778.0
NHP2 -6740.0 -12267.0
NIP7 -15328.0 -15460.0
NOB1 -6653.0 -15190.0
NOC4L -12566.0 -8906.0
NOL11 -13708.0 -7588.0
NOL12 -4233.0 -5271.0
NOL6 1036.0 -9213.0
NOL9 -15751.0 -6965.0
NOP10 -4416.0 1326.0
NOP14 -6525.0 -7972.0
NOP2 -13475.0 -14287.0
NOP56 -4751.0 -9699.0
NOP58 -1224.0 -13035.0
NSRP1 2103.0 -8636.0
NSUN2 -3940.0 -10093.0
NSUN4 -5053.0 -9573.0
NSUN6 -4511.0 -4749.0
NT5C3B -9392.0 -13489.0
NUDT21 -2241.0 -14210.0
NUP107 -7236.0 -8001.0
NUP133 -2470.0 -9143.0
NUP153 -14779.0 -17257.0
NUP155 -12129.0 -15214.0
NUP160 -11625.0 -12148.0
NUP188 -7877.0 -15187.0
NUP205 -7637.0 -436.0
NUP210 -10939.0 -191.0
NUP214 -13610.0 -5777.0
NUP35 -1428.0 -7296.0
NUP37 -15153.0 -17285.0
NUP42 -8725.0 -15797.0
NUP43 -6734.0 -13552.0
NUP50 -14109.0 -5828.0
NUP54 -12929.0 -7747.0
NUP58 -9205.0 -15350.0
NUP62 -3466.0 -2332.0
NUP85 -4129.0 -11356.0
NUP88 -7189.0 -10830.0
NUP93 -3140.0 -9015.0
NUP98 -8145.0 -10870.0
NXF1 -8852.0 -11115.0
NXT1 -12398.0 -17072.0
OSGEP -9832.0 -14157.0
PABPC1 -6557.0 -12965.0
PABPN1 -3138.0 -3917.0
PAIP1 -13837.0 -9401.0
PAN2 -11345.0 -2347.0
PAN3 -7617.0 -6521.0
PAPOLA -16101.0 -15712.0
PARN -1748.0 -10005.0
PATL1 -11836.0 -14129.0
PCBP1 -10169.0 -16427.0
PCBP2 -1886.0 -98.0
PCF11 -3445.0 -13228.0
PDCD11 -12738.0 -9602.0
PDCD7 -13540.0 -8157.0
PELP1 -2276.0 97.0
PES1 -2829.0 429.0
PHAX -4090.0 -14867.0
PHF5A 250.0 -11085.0
PLRG1 -2705.0 -3336.0
PNN -11304.0 -12418.0
PNO1 -9426.0 -14472.0
PNRC2 -15485.0 -16726.0
POLDIP3 -15594.0 -7119.0
POLR2A 281.0 -12598.0
POLR2B -6420.0 -12168.0
POLR2C -9988.0 -16056.0
POLR2D -5476.0 -17166.0
POLR2E -6353.0 -15885.0
POLR2F -11988.0 -11623.0
POLR2G 1063.0 -12103.0
POLR2H -12591.0 -11738.0
POLR2I -5956.0 -15772.0
POLR2J -11626.0 -4910.0
POLR2K -1330.0 590.0
POLR2L -16149.0 -16420.0
POM121 -13119.0 -11642.0
POM121C -3009.0 -6792.0
POP1 -6247.0 -16499.0
POP4 395.0 -5118.0
POP5 -3203.0 -10935.0
POP7 -5863.0 -13522.0
PPIE 836.0 77.0
PPIG -8963.0 -4684.0
PPIH -3666.0 -9474.0
PPIL1 -2175.0 -5065.0
PPIL2 -8250.0 -6840.0
PPIL3 -8510.0 -12194.0
PPIL4 -13448.0 -15489.0
PPP1R8 -1183.0 -16138.0
PPP2CA -16303.0 -14663.0
PPP2R1A -5112.0 -15337.0
PPP2R2A -14638.0 -5917.0
PPWD1 -3128.5 -15365.0
PRCC 1835.0 -3684.0
PRKCA -1.0 -3348.0
PRKCD -13406.0 -5373.0
PRKRIP1 -6127.0 -9646.0
PRMT5 -4800.0 -629.0
PRORP -2590.0 -11245.0
PRPF18 -113.0 -7334.0
PRPF19 -10166.0 -16418.0
PRPF3 -14854.0 -3283.0
PRPF31 -9151.0 -8721.0
PRPF38A -5974.0 -1739.0
PRPF4 -4269.0 -7783.0
PRPF40A -12872.0 -12830.0
PRPF6 -580.0 -4254.0
PRPF8 -2174.0 -6225.0
PSMA1 -8781.0 -2177.0
PSMA2 -7391.0 -13190.0
PSMA3 -543.0 -12585.0
PSMA4 -1489.0 -11130.0
PSMA5 -5612.0 -12086.0
PSMA6 -5453.0 -7068.0
PSMA7 -15238.0 -16097.0
PSMA8 -12998.0 1341.0
PSMB1 -7998.0 -12452.0
PSMB10 1546.0 -12645.0
PSMB11 -7675.0 461.0
PSMB2 -15087.0 -14324.0
PSMB3 -2943.0 -16574.0
PSMB4 -3092.0 -17193.0
PSMB5 -2173.0 -13304.0
PSMB6 -1270.0 -15778.0
PSMB7 1688.0 1166.0
PSMB8 251.0 -10098.0
PSMB9 -4477.0 -14712.0
PSMC1 -2414.0 -13145.0
PSMC2 -315.0 -2310.0
PSMC3 -7461.0 -17123.0
PSMC4 459.0 -4407.0
PSMC5 -9725.0 -12293.0
PSMC6 -7301.0 332.0
PSMD1 -15755.0 -15264.0
PSMD11 -6796.0 -15996.0
PSMD12 -13229.0 -1837.0
PSMD13 -9340.0 -12191.0
PSMD14 -9752.0 -14404.0
PSMD2 -5101.0 -4469.0
PSMD3 -6030.0 -12489.0
PSMD4 -6049.0 -14518.0
PSMD5 2564.0 -8724.0
PSMD6 -5979.0 -12939.0
PSMD7 -12233.0 -5710.0
PSMD8 -9781.0 -13888.0
PSMD9 -11408.0 -10645.0
PSME1 -9760.0 -16962.0
PSME2 67.0 -15711.0
PSME3 -4965.0 -13719.0
PSME4 -13130.0 -13058.0
PSMF1 -12443.0 -3758.0
PTBP1 -7738.0 -7034.0
PUF60 -13313.0 -8685.0
PUS1 -9047.0 -8402.0
PUS3 -13563.0 -15952.0
PUS7 -10698.0 -15294.0
PWP2 -16374.0 -4256.0
QTRT1 -5850.0 -6579.0
QTRT2 -10039.0 -17079.0
RAE1 -10699.0 -7730.0
RAN -10662.0 -16269.0
RANBP2 -8430.0 -15721.0
RBM17 -8943.0 -5843.0
RBM22 -12442.0 -10854.0
RBM25 -7406.0 -9102.0
RBM28 -708.0 -11389.0
RBM39 -3321.0 -9939.0
RBM42 439.0 -12508.0
RBM5 -336.0 -9736.0
RBM7 -8351.0 -7134.0
RBM8A -8207.0 -1247.0
RCL1 -4953.0 -7784.0
RIOK1 -13823.0 -10020.0
RIOK2 -12639.0 -1643.0
RIOK3 -14847.0 -338.0
RNGTT -13776.0 -3113.0
RNMT -12479.0 -16072.0
RNPC3 -8856.0 -7199.0
RNPS1 -15843.0 -6534.0
RPL10A -4327.0 -16688.0
RPL10L -4672.0 1242.0
RPL11 -7730.0 -11362.0
RPL12 -1818.0 -7657.0
RPL13 -13096.0 -17048.0
RPL13A -1938.5 -10955.5
RPL14 -8334.0 -15519.0
RPL15 -13598.0 -15972.0
RPL17 -4720.0 -15113.0
RPL18 -6084.0 -16405.0
RPL18A -13854.0 -12314.0
RPL19 -9925.0 -950.0
RPL21 -9899.5 -13500.5
RPL22 -2661.0 -13474.0
RPL22L1 -2679.0 -16975.0
RPL23 -3278.0 -4599.0
RPL23A -8489.0 -13877.0
RPL24 813.0 329.0
RPL26 -7851.0 -14206.0
RPL26L1 -4159.0 -17223.0
RPL27 -10972.0 -14660.0
RPL27A -11040.0 -16640.0
RPL28 -7060.0 -12491.0
RPL29 -6766.0 -14551.0
RPL3 -4433.0 -6744.0
RPL30 -3473.0 -13276.0
RPL31 160.0 -9807.0
RPL32 -8290.0 -7245.0
RPL34 -3639.0 913.0
RPL35 -12031.0 -16424.0
RPL35A -563.0 -483.0
RPL36 -15878.0 -16971.0
RPL36AL -12581.0 -15545.0
RPL37 -5636.0 -11980.0
RPL37A -8914.0 -12749.0
RPL38 -3414.0 -3066.0
RPL39L -2329.0 -16531.0
RPL3L -13013.0 328.0
RPL4 -7696.0 199.0
RPL41 -8377.0 -15742.0
RPL5 1478.0 -13656.0
RPL6 718.0 -2953.0
RPL7 -11616.0 -15741.0
RPL7A -11184.0 -3709.0
RPL8 -16023.0 -13701.0
RPL9 -4066.0 -291.0
RPLP0 -7445.0 -14511.0
RPLP1 -5049.0 -3663.0
RPLP2 -14824.0 -14743.0
RPP14 -8364.0 -10025.0
RPP21 -8006.0 -11507.0
RPP25 -3896.0 -16883.0
RPP30 -11196.0 -2239.0
RPP38 -5496.0 -16696.0
RPP40 -6839.0 -9297.0
RPPH1 -15738.0 -10255.0
RPS10 -11363.0 -14602.0
RPS11 -12666.0 -8009.0
RPS12 -5554.0 -5380.0
RPS13 541.0 -12870.0
RPS14 -14985.0 -576.0
RPS15 -11816.0 -15841.0
RPS15A 1563.0 -10896.0
RPS16 -12775.0 -13973.0
RPS17 363.0 -17286.0
RPS18 -5492.0 -6509.0
RPS19 -4848.0 -463.0
RPS2 -8403.0 -13161.0
RPS20 -9963.0 -9064.0
RPS21 -14247.0 -15846.0
RPS23 -4455.0 -10331.0
RPS24 1255.0 -3232.0
RPS25 -2544.0 -11699.0
RPS26 802.0 -7841.0
RPS27 1722.0 -11381.0
RPS27A -11481.0 -2147.0
RPS27L -9482.0 -16569.0
RPS28 -12352.0 -15277.0
RPS29 -8298.0 -16523.0
RPS3 1404.0 -10369.0
RPS3A -10279.0 -15494.0
RPS5 -15070.0 -15693.0
RPS6 -16407.0 -6799.0
RPS7 -3124.0 -12481.0
RPS8 -9073.0 -1281.0
RPS9 -11982.0 -623.0
RPSA -4693.0 -3295.0
RRP1 -10726.0 -13330.0
RRP36 -1521.0 -12565.0
RRP7A -6927.0 -15826.0
RRP9 -14440.0 -14383.0
RTCB -9353.0 -11164.0
RTRAF -3517.0 -8461.0
SAP18 -8346.0 -9242.0
SARNP -3441.0 -1564.0
SART1 -1236.0 -6561.0
SDE2 -11312.0 -11143.0
SEC13 -8604.0 -10471.0
SEH1L -8901.0 -14935.0
SEM1 -1388.0 -14801.0
SENP3 -4425.0 -16216.0
SET -8737.0 -6532.0
SF1 -10586.0 -6786.0
SF3A1 -9477.0 -3830.0
SF3A2 -1539.0 -12886.0
SF3A3 -7627.0 -13984.0
SF3B1 -3327.0 -4670.0
SF3B2 -14806.0 -15750.0
SF3B3 -8037.0 -12368.0
SF3B4 -10782.0 -304.0
SF3B5 -10643.0 -4270.0
SKIC2 -2640.0 -3819.0
SKIC3 -11945.0 -9870.0
SKIC8 -9348.0 -3901.0
SLBP -10454.0 -14847.0
SLU7 -310.0 -11064.0
SMG1 -1136.0 -10950.0
SMG5 -7650.0 -7428.0
SMG6 -1586.0 -6031.0
SMG7 -3787.0 -17180.0
SMG8 224.0 -16983.0
SMG9 -14689.0 -625.0
SMN1 -15845.5 1558.5
SMN2 -15845.5 1558.5
SMNDC1 505.0 -15061.0
SMU1 -1032.0 -13197.0
SNIP1 -222.0 -10344.0
SNRNP200 -9880.0 -12743.0
SNRNP25 -6129.0 -15241.0
SNRNP27 2.0 -16643.0
SNRNP35 -1585.0 -5122.0
SNRNP40 -15294.0 -16098.0
SNRNP48 -12705.0 -2563.0
SNRNP70 -412.0 -2675.0
SNRPA -9662.0 -5775.0
SNRPA1 -10965.0 -13829.0
SNRPB -927.0 -684.0
SNRPB2 -13325.0 -2526.0
SNRPC -10677.0 -16363.0
SNRPD1 -6663.0 -17082.0
SNRPD2 -5707.0 -10042.0
SNRPD3 1994.0 -13738.0
SNRPE -6157.0 -1244.0
SNRPF -12336.0 -12075.0
SNRPG -15044.0 -13747.0
SNRPN -11883.0 -827.0
SNU13 -4140.0 -11984.0
SNUPN -11643.0 -9116.0
SNW1 -4711.0 -3629.0
SRRM1 -15455.0 -10860.0
SRRM2 -2803.0 -7642.0
SRRT 1248.0 -2644.0
SRSF1 -1936.0 -13625.0
SRSF10 -9606.0 -6278.0
SRSF11 -13230.0 -9481.0
SRSF12 -4491.0 -7612.0
SRSF2 -14070.0 -17242.0
SRSF3 -8788.0 -9919.0
SRSF4 -15695.0 -14432.0
SRSF5 -7324.0 -3316.0
SRSF6 -10229.0 -12794.0
SRSF7 -5755.0 -13406.0
SRSF8 -8246.0 -10864.0
SRSF9 -11326.0 -17076.0
SUGP1 -10222.0 -2277.0
SUPT5H -12113.0 -11711.0
SYF2 -3367.0 -7194.0
SYMPK -3587.0 -9784.0
TBL3 -13436.0 -6770.0
TCERG1 -1377.0 -4364.0
TEX10 -768.0 -9089.0
TFB1M -4717.0 -14189.0
TFIP11 -985.0 -14960.0
TGS1 -7408.0 -16254.0
THADA -1337.0 -2908.0
THG1L 1188.0 -5042.0
THOC1 -13496.0 -12931.0
THOC3 1025.0 -6860.0
THOC5 -7076.0 -13735.0
THOC6 -9681.0 -2837.0
THOC7 -15935.0 -12396.0
THUMPD1 -6716.0 186.0
TNFSF13 -2818.0 -318.0
TNKS1BP1 -5616.0 -3233.0
TNPO1 -12905.0 -8329.0
TP53RK -8877.0 -5629.0
TPR -12390.0 -14677.0
TPRKB -46.0 -10383.0
TRA2B -5013.0 -247.0
TRDMT1 -5126.0 -15562.0
TRIT1 -9030.0 -15351.0
TRMT1 -11729.0 -15557.0
TRMT10A -4791.0 -3339.0
TRMT10C -5143.0 -14640.0
TRMT11 -2707.0 -10757.0
TRMT112 -15892.0 -17246.0
TRMT12 2267.0 1361.0
TRMT13 -2809.0 -10634.0
TRMT44 -654.0 -158.0
TRMT5 -1385.0 -14147.0
TRMT6 -5520.0 -9734.0
TRMT61A -1675.0 -2531.0
TRMT61B -10124.0 -13102.0
TRMT9B -12820.0 -9656.0
TRMU -8154.0 -15456.0
TRNT1 -10818.0 -15627.0
TSEN15 -14025.0 -3894.0
TSEN2 -6607.0 -10570.0
TSEN34 -13266.0 -16061.0
TSEN54 -16030.0 -15578.0
TSR1 -8085.0 -15825.0
TSR3 -13343.0 -14106.0
TUT4 -10874.0 -2309.0
TUT7 -12311.0 -16425.0
TXNL4A -6925.0 -8542.0
TYW1 -8652.0 -11070.0
TYW3 1154.0 -16528.0
TYW5 -7638.0 -15684.0
U2AF1 -13274.0 -14544.0
U2AF1L4 -1258.0 -10948.0
U2AF2 -11577.0 -15695.0
U2SURP -13904.0 -14276.0
UBA52 -10894.0 -4996.0
UBB -12784.0 -8060.0
UBC -11566.0 -692.0
UBL5 -14675.0 -8655.0
UPF1 -8148.0 -2382.0
UPF2 -5215.0 -9117.0
UPF3A -4036.0 -16210.0
URM1 1159.0 -7404.0
USP39 -5794.0 -10070.0
UTP11 -3270.0 -12685.0
UTP14C 2455.0 208.0
UTP15 -10573.5 -12890.0
UTP18 -9890.0 -10957.0
UTP20 -10214.0 -6804.0
UTP25 -1275.0 -7555.0
UTP3 -1737.0 -4729.0
UTP4 -12761.0 -16727.0
UTP6 -8714.0 -4562.0
WBP11 -808.0 -2492.0
WBP4 -15009.0 -15570.0
WDR12 -14637.0 -13573.0
WDR18 -14866.0 237.0
WDR3 -7575.0 -10583.0
WDR33 -4585.0 -13497.0
WDR36 -564.0 -8116.0
WDR4 -11046.0 -6774.0
WDR43 -15840.0 -10013.0
WDR46 -879.0 -6060.0
WDR70 -10535.0 -4839.0
WDR75 -3171.0 -9088.0
WDR77 -5895.0 -16321.0
WTAP -15597.0 -13290.0
XAB2 -1828.0 -2889.0
XPO1 -11418.0 -13329.0
XPOT -9162.0 -16681.0
XRN1 -946.0 -13885.0
XRN2 -11612.0 -14144.0
YBX1 -14292.0 -7832.0
YJU2 -6260.0 -5708.0
YWHAB -12447.0 -2244.0
YWHAZ -11791.0 -10782.0
ZBTB8OS -12713.0 -13083.0
ZC3H11A -6761.0 -6913.0
ZCRB1 -13380.0 -3405.0
ZFP36 -14241.0 -1344.0
ZFP36L1 -9728.0 -16111.0
ZMAT2 -3019.0 -11910.0
ZMAT5 -9196.0 -14958.0
ZNF473 -13291.0 -10477.0
ZNF830 -7829.5 -13891.0



REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE
metric value
setSize 123
pMANOVA 9.21e-16
p.adjustMANOVA 2.16e-13
s.dist 0.474
s.Estill 0.228
s.Novakovic 0.416
p.Estill 1.26e-05
p.Novakovic 1.65e-15




Top 20 genes
Gene Estill Novakovic
SPRR2E 2708 1797
SPRR2G 2709 1526
SPRR2B 1675 1609
SPRR2D 1935 1345
LCE1A 1573 1446
CASP14 2396 766
LCE2B 1713 904
LCE3D 2432 619
KRT25 1117 1032
PI3 547 1296
SPRR3 676 958
SPRR1A 1764 290
LELP1 157 1478

Click HERE to show all gene set members

All member genes
Estill Novakovic
CAPN1 -7033 -14567
CAPNS1 -8831 -7934
CASP14 2396 766
CDSN -7678 -2686
CELA2A 1198 -2527
CSTA -2236 1823
DSC1 2561 -10422
DSC2 -16340 -15466
DSC3 -14244 -16337
DSG1 -4627 -8279
DSG2 -10991 264
DSG3 -16377 -2322
DSP -9347 -11219
EVPL -6516 -1883
FLG -4195 908
FURIN -10334 -10318
IVL -746 -13412
JUP -8132 -2088
KAZN -4924 -4018
KLK12 -4356 39
KLK13 -4378 -10050
KLK14 -8357 232
KLK5 1372 -2329
KLK8 -9418 -1455
KRT1 1817 -3547
KRT10 -5351 -13637
KRT12 -2258 1525
KRT13 -5970 -3946
KRT14 -14882 847
KRT15 -13794 -6292
KRT16 -13124 -2267
KRT17 -12130 1210
KRT18 -15366 -8229
KRT19 -13618 -9580
KRT2 1518 -3197
KRT20 -1612 -841
KRT23 -3237 -2254
KRT24 -4681 -3540
KRT25 1117 1032
KRT26 -2139 -10372
KRT27 -470 -2770
KRT28 -2652 641
KRT3 -726 -7513
KRT31 85 -3925
KRT32 -11953 851
KRT33A -4894 -13087
KRT33B 1795 -8530
KRT34 -4854 -3996
KRT35 -3615 -6235
KRT36 -2413 760
KRT37 164 -6405
KRT38 1907 -3814
KRT39 2379 -6551
KRT4 -7475 -6614
KRT40 1316 -4981
KRT5 -2586 -131
KRT6A -789 1400
KRT6B -196 -3898
KRT6C -554 -1792
KRT7 -12475 -9283
KRT71 -11002 -804
KRT72 -9489 -4682
KRT73 -5884 -1913
KRT74 -13958 448
KRT75 -12519 1652
KRT76 -9108 -1825
KRT77 431 -9683
KRT78 -16173 -5378
KRT79 -9222 -6022
KRT8 -6155 -5219
KRT80 -13043 -3151
KRT81 -9609 74
KRT82 -9044 -533
KRT83 -14776 -1105
KRT84 -1564 -3879
KRT85 -8721 775
KRT86 -11530 -11977
KRT9 -12756 1355
LCE1A 1573 1446
LCE1B 1038 -6328
LCE1C 1390 -1417
LCE1D 636 -1176
LCE1E -4730 1374
LCE1F -5456 1372
LCE2A 1265 -2384
LCE2B 1713 904
LCE2C -9805 -16162
LCE2D -10171 -1279
LCE3A -4875 1023
LCE3D 2432 619
LCE3E 641 -1317
LCE4A 2086 -18
LCE5A -6820 -3063
LCE6A 2381 -2116
LELP1 157 1478
LIPJ 1568 -425
LIPK 1207 -8439
LIPM 105 -12169
PCSK6 -516 -2478
PERP -5431 -16142
PI3 547 1296
PKP1 -6331 -6258
PKP2 -15110 -346
PKP3 -6359 -4582
PKP4 -3941 -6202
PPL -3523 -7230
PRSS8 -9013 -420
RPTN -895 -8692
SPINK5 -16373 -16126
SPINK9 2301 -8431
SPRR1A 1764 290
SPRR1B -1830 316
SPRR2A 1250 -4207
SPRR2B 1675 1609
SPRR2D 1935 1345
SPRR2E 2708 1797
SPRR2F -11348 -409
SPRR2G 2709 1526
SPRR3 676 958
ST14 -4421 510
TCHH -278 -3162
TGM1 -7665 819
TGM5 -894 -970



REACTOME_ANTIMICROBIAL_PEPTIDES

REACTOME_ANTIMICROBIAL_PEPTIDES
metric value
setSize 81
pMANOVA 1.2e-14
p.adjustMANOVA 2.46e-12
s.dist 0.565
s.Estill 0.29
s.Novakovic 0.485
p.Estill 6.64e-06
p.Novakovic 4.28e-14




Top 20 genes
Gene Estill Novakovic
DEFB107A 2598.5 1795.5
DEFB107B 2598.5 1795.5
DEFB108B 2344.0 1629.0
TLR1 2511.0 1284.0
RNASE7 1838.0 1503.0
DEFB119 1643.0 1432.0
REG3G 1361.0 1174.0
DEFA6 1507.0 941.0
DEFB118 672.0 1474.0
CCR2 803.0 1211.0
PI3 547.0 1296.0
RNASE3 2300.0 228.0
ITLN1 2689.0 159.0
SEMG1 172.0 371.0

Click HERE to show all gene set members

All member genes
Estill Novakovic
ART1 -4686.0 -12705.0
ATOX1 -10773.0 -11190.0
BPI -14643.0 -2327.0
BPIFA1 -41.0 234.0
BPIFA2 -8447.0 -197.0
BPIFB1 -10860.0 -6603.0
BPIFB2 534.0 -9118.0
BPIFB4 -1436.0 -4767.0
BPIFB6 -6923.0 -2117.0
CAMP -11868.0 -1781.0
CCR2 803.0 1211.0
CCR6 -1100.0 -957.0
CD4 -1950.0 -3627.0
CHGA -13831.0 -13589.0
CLU -4915.0 -6709.0
CTSG -1839.0 1031.0
DCD -5368.0 -1495.0
DEFA1 -10502.5 1731.5
DEFA1B -10502.5 1731.5
DEFA3 -15955.0 1682.0
DEFA4 -8431.0 845.0
DEFA5 -4268.0 -11694.0
DEFA6 1507.0 941.0
DEFB1 -615.0 268.0
DEFB104A 935.5 -12213.5
DEFB104B 935.5 -12213.5
DEFB105A 1628.5 -1143.5
DEFB105B 1628.5 -1143.5
DEFB106A -428.5 -11168.5
DEFB106B -428.5 -11168.5
DEFB107A 2598.5 1795.5
DEFB107B 2598.5 1795.5
DEFB108B 2344.0 1629.0
DEFB115 -4185.0 -777.0
DEFB116 -11320.0 513.0
DEFB118 672.0 1474.0
DEFB119 1643.0 1432.0
DEFB121 -1563.0 -4576.0
DEFB123 -11869.0 1547.0
DEFB124 -5916.0 -515.0
DEFB125 -2711.0 1689.0
DEFB126 2588.0 -6168.0
DEFB127 539.0 -299.0
DEFB128 1601.0 -5013.0
DEFB129 2437.0 -6648.0
DEFB131A -14407.0 -1462.0
DEFB132 -13625.0 518.0
DEFB133 -16387.0 1494.0
DEFB134 -14899.0 -10385.0
DEFB135 650.0 -1392.0
DEFB136 -6556.0 -15810.0
ELANE -6154.0 1156.0
EPPIN 627.0 -9968.0
GNLY -1371.0 436.0
ITLN1 2689.0 159.0
LCN2 -15262.0 -233.0
LEAP2 2291.0 -16359.0
LTF -12612.0 -11920.0
LYZ -8882.0 1881.0
PGLYRP1 -16301.0 -13781.0
PGLYRP2 -4758.0 -194.0
PGLYRP3 2553.0 -3382.0
PGLYRP4 -1383.0 -3139.0
PI3 547.0 1296.0
PLA2G2A -8360.0 -655.0
PRSS3 -10686.0 -1439.0
PRTN3 -15270.0 1251.0
REG3A 2662.0 -1380.0
REG3G 1361.0 1174.0
RNASE3 2300.0 228.0
RNASE6 347.0 -1607.0
RNASE7 1838.0 1503.0
RNASE8 1341.0 -5117.0
S100A7 -5083.0 -4719.0
S100A7A -2019.0 164.0
S100A8 -4054.0 543.0
S100A9 -2035.0 462.0
SEMG1 172.0 371.0
SLC11A1 -9740.0 -1379.0
TLR1 2511.0 1284.0
TLR2 -3109.0 -15818.0



REACTOME_CELL_CYCLE

REACTOME_CELL_CYCLE
metric value
setSize 667
pMANOVA 1.64e-13
p.adjustMANOVA 2.99e-11
s.dist 0.191
s.Estill -0.0927
s.Novakovic -0.167
p.Estill 4.61e-05
p.Novakovic 2.32e-13




Top 20 genes
Gene Estill Novakovic
E2F1 -16127.0 -16773
CDKN2B -15666.0 -17173
DBF4 -15835.5 -16964
POLR2L -16149.0 -16420
NUP37 -15153.0 -17285
H3C12 -15164.0 -17158
NUP153 -14779.0 -17257
MAD2L1 -14859.0 -17139
CDCA5 -15196.0 -16601
KIF23 -15518.0 -16131
ATRIP -16346.0 -15271
CDKN2D -14848.0 -16781
CDKN1C -15390.0 -16189
PSMA7 -15238.0 -16097
SMC3 -14879.0 -16404
TUBG1 -16375.0 -14891
MCM4 -14468.0 -16835
TUBA1B -14029.0 -17230
PSMD1 -15755.0 -15264
CENPO -14764.0 -16262

Click HERE to show all gene set members

All member genes
Estill Novakovic
AAAS -5233.0 -3868.0
ABL1 -712.0 -2410.0
ABRAXAS1 -9135.0 -15398.0
ACD -6267.0 -6892.5
ACTR1A -10774.0 -9995.0
AHCTF1 -2570.0 -3624.0
AJUBA -4874.0 -10340.0
AKAP9 -11760.0 -8323.0
AKT1 -6145.0 -2432.0
AKT2 -12142.0 -6370.0
AKT3 -835.0 -5588.0
ALMS1 -10177.0 -1025.0
ANAPC1 -2324.0 -5744.0
ANAPC10 -11343.0 -5816.0
ANAPC11 -15553.0 -3569.0
ANAPC15 -5573.0 -1354.0
ANAPC16 -3464.0 -3219.0
ANAPC2 -8367.0 -1213.0
ANAPC4 -11051.0 -6188.0
ANAPC5 -7613.0 -11860.0
ANAPC7 -6389.0 -4274.0
ANKLE2 -990.0 -8487.0
ANKRD28 -6283.0 -1742.0
ARPP19 -15292.0 -9905.0
ATM -10666.0 -3054.0
ATR -5921.0 -15232.0
ATRIP -16346.0 -15271.0
AURKA -8302.0 -8099.0
AURKB -585.0 -2715.0
B9D2 -6475.0 -5577.0
BABAM1 -7407.0 -16872.0
BABAM2 -2016.0 -4347.0
BANF1 -12198.0 -14222.0
BARD1 -9780.0 -7224.0
BIRC5 -509.0 -2514.0
BLM -8164.0 -12810.0
BLZF1 293.5 -15228.0
BORA -5571.0 -12042.0
BRCA1 2021.0 628.0
BRCA2 -9972.0 -9971.0
BRIP1 1640.0 -14117.0
BTRC -8741.0 -7184.0
BUB1 -406.0 -13771.0
BUB1B -2372.0 -6560.0
BUB3 -3718.0 -13578.0
CABLES1 -9757.0 -8072.0
CC2D1B -2031.0 -14994.0
CCNA1 -11907.0 -12984.0
CCNA2 -6087.0 -16501.0
CCNB1 -15812.0 -8791.0
CCNB2 -5698.0 -12010.0
CCND1 -3494.0 -11443.0
CCND2 -9651.0 -15597.0
CCND3 -13014.0 -8722.0
CCNE1 -14226.0 -16873.0
CCNE2 -10192.0 -8331.0
CCNH -7680.0 -16219.0
CCP110 -7242.0 -11338.0
CDC14A -2110.0 -10449.0
CDC16 -3120.0 -6337.0
CDC20 -14422.0 -10269.0
CDC23 -4732.0 -5268.0
CDC25A -9632.0 -11288.0
CDC25B 1208.0 -14662.0
CDC25C -5672.0 -11011.0
CDC26 -5432.0 -868.0
CDC27 -8038.0 -11129.0
CDC45 -6700.0 80.0
CDC6 -9764.0 -8910.0
CDC7 -9686.0 -12389.0
CDCA5 -15196.0 -16601.0
CDCA8 -11699.0 -15979.0
CDK1 -629.5 -12551.0
CDK11A -4310.0 -10831.0
CDK11B -3175.0 -2746.0
CDK2 -241.0 -10000.0
CDK4 -12590.0 -14349.0
CDK5RAP2 866.0 -2873.0
CDK6 -7466.0 -5435.0
CDK7 -11455.0 -8357.0
CDKN1A -7625.0 -12022.0
CDKN1B -15950.0 -12998.0
CDKN1C -15390.0 -16189.0
CDKN2A -13143.0 -1475.0
CDKN2B -15666.0 -17173.0
CDKN2C -9649.0 -15409.0
CDKN2D -14848.0 -16781.0
CDT1 -15570.0 -14862.0
CENPA -6563.0 -11218.0
CENPC -2493.0 -14292.0
CENPE -9573.0 -14208.0
CENPF -1734.0 -5756.0
CENPH -2153.0 -17067.0
CENPJ -3229.0 -6985.0
CENPK -3128.5 -16484.0
CENPL -3296.0 -14202.0
CENPM -13815.0 -6658.0
CENPN -5955.0 -11949.0
CENPO -14764.0 -16262.0
CENPP 1162.0 -12025.0
CENPQ -313.0 -6294.0
CENPS -7432.0 -6760.0
CENPT -13891.0 -13739.0
CENPU -13118.0 -12622.0
CENPW -5286.0 790.0
CEP131 -3422.0 -4824.0
CEP135 -16264.0 -14394.0
CEP152 -3924.0 -12738.0
CEP164 -13.0 -12119.0
CEP192 -5821.0 -2921.0
CEP250 -7889.0 -8951.0
CEP290 -346.0 -14952.0
CEP41 -7749.0 -15982.0
CEP43 -13278.0 -16552.0
CEP57 -15253.0 -12008.0
CEP63 -12858.0 -11039.0
CEP70 -8386.0 -8265.0
CEP72 -52.0 -4610.0
CEP76 -12726.0 -16607.0
CEP78 -11770.0 -9754.0
CHEK1 -5590.0 -8025.0
CHEK2 -2471.0 -14997.0
CHMP2A -6394.0 -196.0
CHMP2B -13036.0 -15756.0
CHMP3 -7699.0 8.0
CHMP4A -8786.0 -640.0
CHMP4B -15007.0 -3831.0
CHMP4C -11740.0 -15669.0
CHMP6 -13294.0 -8756.0
CHMP7 -3337.0 -3187.0
CHTF18 -8348.0 -9353.0
CHTF8 -12641.0 -14556.0
CKAP5 -7709.0 -13566.0
CKS1B -2079.0 -12778.0
CLASP1 -368.0 -10453.0
CLASP2 -14327.0 -9568.0
CLIP1 -2981.0 -8081.0
CLSPN -6560.0 -13561.0
CNEP1R1 -10579.0 -7355.0
CNTRL -4976.0 -2353.0
COP1 -12587.0 -4949.0
CSNK1D -10315.0 -2827.0
CSNK1E -12689.0 -11824.0
CSNK2A1 -10932.0 -4915.0
CSNK2A2 -15748.0 -7535.0
CSNK2B -367.0 -14595.0
CTC1 -2453.0 -13247.0
CTDNEP1 -7063.0 -14859.0
CUL1 -2215.0 449.0
DAXX -5751.0 -1962.0
DBF4 -15835.5 -16964.0
DCTN1 69.0 -10034.0
DCTN2 -6153.0 -1119.0
DCTN3 -12480.0 -10976.0
DHFR -5630.0 -14689.0
DIDO1 -8977.0 -11107.0
DMC1 -10360.0 -16024.0
DNA2 -3490.0 -12624.0
DSCC1 -11016.0 -15329.0
DSN1 -11787.0 -7717.0
DYNC1H1 48.0 -3145.0
DYNC1I1 -7317.0 -6097.0
DYNC1I2 1732.0 -12829.0
DYNC1LI1 -11159.0 -13138.0
DYNC1LI2 -12760.0 -7326.0
DYNLL1 -11160.0 -14050.0
DYNLL2 -13828.0 -13633.0
DYRK1A -9208.0 -5694.0
E2F1 -16127.0 -16773.0
E2F2 -13924.0 -7662.0
E2F3 -4245.0 -3475.0
E2F4 -12111.0 -13562.0
E2F5 -13411.0 -7919.0
E2F6 -5691.0 -3256.0
EML4 -12051.0 -11469.0
ENSA -2087.0 -5115.0
EP300 -1567.0 -10732.0
ESCO1 -13101.0 -9854.0
ESCO2 1100.0 -7532.0
ESPL1 -8703.0 -4634.0
EXO1 -10822.0 -13991.0
FBXL18 -3865.0 -1826.0
FBXL7 -618.0 -4837.0
FBXO5 -15003.0 -15440.0
FBXW11 -2863.0 -8621.0
FEN1 -3850.0 -9060.0
FKBP6 -307.0 860.0
FKBPL -3648.0 -9083.0
FOXM1 -9091.0 -6861.0
FZR1 -7455.0 -2900.0
GAR1 -10289.0 -10526.0
GINS1 -5314.0 -15131.0
GINS2 -6809.0 -14649.0
GINS3 -306.0 -3695.0
GINS4 -2971.0 -1628.0
GMNN -2029.0 -11012.0
GOLGA2 -5423.0 558.0
GORASP1 -15871.0 -8506.0
GORASP2 -2113.0 -10129.0
GSK3B -13275.0 -5625.0
GTSE1 -13342.0 -12313.0
H2AC14 -740.0 -6291.0
H2AC18 -10109.5 -16821.5
H2AC19 -10109.5 -16821.5
H2AC20 -9365.0 -421.0
H2AC4 -8682.0 -7652.0
H2AC6 -3772.0 -14402.0
H2AC7 -10309.0 -3529.5
H2AC8 -15265.0 -12472.0
H2AJ -360.0 -16792.0
H2AX -13329.0 -16764.0
H2AZ1 -10477.0 -10825.0
H2AZ2 -15177.0 -12968.0
H2BC1 930.5 1414.0
H2BC10 -12140.0 -5784.0
H2BC11 -4716.0 -15808.0
H2BC12 -3961.0 -14793.0
H2BC13 -11400.0 761.0
H2BC14 -1609.0 -8267.0
H2BC15 -2744.0 -168.0
H2BC17 -16322.0 -3166.0
H2BC21 -8996.0 -6316.0
H2BC26 -11379.0 -16861.0
H2BC3 -15205.0 -10594.0
H2BC4 -10641.0 -8955.0
H2BC5 -9533.0 315.0
H2BC6 -15206.0 266.0
H2BC7 -11776.0 -3529.5
H2BC8 -15228.0 -8541.0
H2BC9 -9951.5 -12902.5
H3-3A -13934.0 -14636.0
H3-3B -9143.0 -13971.0
H3-4 1657.0 1580.0
H3C1 -9230.0 -14629.0
H3C10 -3065.0 -374.0
H3C11 -7068.0 -13728.0
H3C12 -15164.0 -17158.0
H3C13 -4294.0 -15204.0
H3C2 -15289.0 -11553.0
H3C3 -6133.0 -14272.0
H3C4 -9971.0 -5667.0
H3C6 371.0 -17250.0
H3C7 -9951.5 -12902.5
H3C8 -15918.0 -12729.0
H4C1 -14459.0 -9617.0
H4C11 854.0 -16001.0
H4C12 -2120.0 -5312.0
H4C13 -334.0 -15402.0
H4C16 -7238.0 -8548.0
H4C2 -7763.0 -2343.0
H4C3 -5978.0 -7968.0
H4C4 -850.0 -16161.0
H4C5 -1971.0 -1886.0
H4C6 -9232.0 -16384.0
H4C8 -3484.0 -14606.0
H4C9 -10105.0 -17149.0
HAUS1 -4546.0 -13080.0
HAUS2 -13309.0 -14657.0
HAUS3 -14922.0 -6957.0
HAUS4 -13307.0 -4175.0
HAUS5 -10024.0 -12724.0
HAUS6 -5085.0 -12244.0
HAUS8 -8315.0 -10096.0
HDAC1 -9758.0 -7989.0
HERC2 1179.0 -69.0
HJURP -4292.0 -13903.0
HMMR -8759.5 -9210.0
HSP90AA1 -13375.0 -9820.0
HSP90AB1 -11098.0 -973.0
HSPA2 -1902.0 -9544.0
HUS1 -1463.0 -13599.0
INCENP -3511.0 -5422.0
IST1 -2314.0 -15295.0
ITGB3BP -11307.0 -12811.0
JAK2 -1045.0 -6197.0
KAT5 -7750.0 -6812.0
KIF18A -11259.0 -13594.0
KIF20A -713.0 -7815.0
KIF23 -15518.0 -16131.0
KIF2A -3632.0 -14056.0
KIF2B 1804.0 1019.0
KIF2C -5345.0 -2415.0
KMT5A -9451.0 -10739.0
KNL1 -5912.0 -5397.0
KNTC1 1079.0 -10240.0
KPNB1 -14539.0 -12059.0
LBR -14393.0 -367.0
LCMT1 -7031.0 -1720.0
LEMD2 -12960.0 -11635.0
LEMD3 -4333.0 -6107.0
LIG1 -15008.0 -2042.0
LIN37 248.0 -14414.0
LIN52 -4993.0 -6014.0
LIN54 -14648.0 -2300.0
LIN9 -14550.0 -8492.0
LMNA -8291.0 -4922.0
LMNB1 -12895.0 -9972.0
LPIN1 -236.0 -5523.0
LPIN2 -14784.0 -7501.0
LPIN3 -12097.0 49.0
LYN -8344.0 -1989.0
MAD1L1 -2331.0 -1491.0
MAD2L1 -14859.0 -17139.0
MAPK1 -9762.0 -6238.0
MAPK3 -14286.0 -1298.0
MAPRE1 -7165.0 -1431.0
MASTL -11213.0 -7101.0
MAU2 -12852.0 -6757.0
MAX -6413.0 -8827.0
MCM10 -909.0 -8152.0
MCM2 -1986.0 -8659.0
MCM3 -5522.0 -10547.0
MCM4 -14468.0 -16835.0
MCM5 -1200.0 -8591.0
MCM6 -11808.0 -8449.0
MCM7 -8495.0 -8481.0
MCM8 -6147.0 -12690.0
MCPH1 -1092.0 -2898.0
MDC1 -2592.0 -10245.0
MDM2 -10651.0 113.0
MDM4 -1979.0 -12057.0
MIS12 -11240.0 -17203.0
MIS18A -16045.0 -11265.0
MIS18BP1 -14055.0 -12461.0
MLH1 -8071.0 -12183.0
MLH3 -14243.0 -3557.0
MNAT1 -2305.0 547.0
MND1 -4213.0 -16243.0
MRE11 -5819.0 -3826.0
MSH4 -2511.0 -15242.0
MSH5 -4932.0 -12752.0
MYBL2 -4276.0 -7558.0
MYC -9179.0 -13967.0
MZT1 -6708.0 -11391.0
MZT2A -11036.0 -14936.0
MZT2B -4632.0 -14385.0
NBN -14657.0 -15359.0
NCAPD2 -2535.0 -716.0
NCAPD3 -10865.0 -11449.0
NCAPG -9210.0 -13713.0
NCAPG2 -8767.0 -6846.0
NCAPH -11798.0 -14186.0
NCAPH2 -16362.0 -13856.0
NDC1 -11478.0 -8778.0
NDC80 -4561.0 -16763.0
NDE1 -5341.0 -4338.0
NDEL1 -13160.0 -13879.0
NEDD1 -5736.0 -2444.0
NEK2 -2328.0 -10364.0
NEK6 -6875.0 -128.0
NEK7 -8135.0 -6091.0
NEK9 -10302.0 -14259.0
NHP2 -6740.0 -12267.0
NINL -11999.0 -5565.0
NIPBL -13657.0 -13686.0
NME7 293.5 -7268.0
NOP10 -4416.0 1326.0
NPM1 -8015.0 460.0
NSD2 -143.0 -5226.0
NSL1 -7434.0 -15145.0
NUDC -14374.0 -13884.0
NUF2 -14033.0 -15760.0
NUMA1 -6928.0 -6650.0
NUP107 -7236.0 -8001.0
NUP133 -2470.0 -9143.0
NUP153 -14779.0 -17257.0
NUP155 -12129.0 -15214.0
NUP160 -11625.0 -12148.0
NUP188 -7877.0 -15187.0
NUP205 -7637.0 -436.0
NUP210 -10939.0 -191.0
NUP214 -13610.0 -5777.0
NUP35 -1428.0 -7296.0
NUP37 -15153.0 -17285.0
NUP42 -8725.0 -15797.0
NUP43 -6734.0 -13552.0
NUP50 -14109.0 -5828.0
NUP54 -12929.0 -7747.0
NUP58 -9205.0 -15350.0
NUP62 -3466.0 -2332.0
NUP85 -4129.0 -11356.0
NUP88 -7189.0 -10830.0
NUP93 -3140.0 -9015.0
NUP98 -8145.0 -10870.0
ODF2 -5350.0 -8504.0
OIP5 -12786.0 -4212.0
OPTN -12236.0 -13140.0
ORC1 -5516.0 -284.0
ORC2 -128.0 -11753.0
ORC3 -10220.0 -14587.0
ORC4 -14431.0 -9786.0
ORC5 -10623.0 -6933.0
ORC6 -10847.0 -16383.0
PAFAH1B1 -7252.0 -9774.0
PCBP4 -14298.0 -11847.0
PCM1 -9358.0 -12737.0
PCNA -15776.0 -14982.0
PCNT -6214.0 -5445.0
PDS5A -5166.0 -9013.0
PDS5B -5500.0 -6377.0
PHF20 -8066.0 -3022.0
PHLDA1 -12682.0 -10557.0
PIAS4 -11745.0 -8067.0
PIF1 1914.0 -9455.0
PKMYT1 -9650.0 -9140.0
PLK1 -6031.0 -5485.0
PLK4 -7554.0 -13381.0
PMF1 -8086.0 -9424.0
POLA2 -11026.0 -12985.0
POLD1 -4311.0 -6454.0
POLD2 -11066.0 470.0
POLD3 -5727.0 -13049.0
POLD4 -1289.0 -13917.0
POLE -6579.0 -2548.0
POLE2 -10276.0 -11861.0
POLE3 -7721.0 -8097.0
POLE4 -14979.0 -14320.0
POLR2A 281.0 -12598.0
POLR2B -6420.0 -12168.0
POLR2C -9988.0 -16056.0
POLR2D -5476.0 -17166.0
POLR2E -6353.0 -15885.0
POLR2F -11988.0 -11623.0
POLR2G 1063.0 -12103.0
POLR2H -12591.0 -11738.0
POLR2I -5956.0 -15772.0
POLR2J -11626.0 -4910.0
POLR2K -1330.0 590.0
POLR2L -16149.0 -16420.0
POM121 -13119.0 -11642.0
POM121C -3009.0 -6792.0
POT1 824.0 -7508.0
PPME1 -3058.0 -14984.0
PPP1CB -3491.0 -9511.0
PPP1CC -14817.0 -9753.0
PPP1R12A -13417.0 -7769.0
PPP1R12B -154.0 -11098.0
PPP2CA -16303.0 -14663.0
PPP2CB -790.0 302.0
PPP2R1A -5112.0 -15337.0
PPP2R1B -6245.0 -9456.0
PPP2R2A -14638.0 -5917.0
PPP2R2D 1861.0 -4520.0
PPP2R5A -14844.0 -2972.0
PPP2R5B -6416.0 -16175.0
PPP2R5C -2004.0 -7658.0
PPP2R5D -13597.0 -16200.0
PPP2R5E -6877.0 -9033.0
PPP6C -7477.0 -14931.0
PPP6R3 -6901.0 -6535.0
PRDM9 1153.0 1123.0
PRIM1 -3625.0 -12956.0
PRIM2 -1166.0 -3820.0
PRKACA -15621.0 -10373.0
PRKAR2B -8749.0 -9071.0
PRKCA -1.0 -3348.0
PRKCB -1287.0 -4560.0
PSMA1 -8781.0 -2177.0
PSMA2 -7391.0 -13190.0
PSMA3 -543.0 -12585.0
PSMA4 -1489.0 -11130.0
PSMA5 -5612.0 -12086.0
PSMA6 -5453.0 -7068.0
PSMA7 -15238.0 -16097.0
PSMA8 -12998.0 1341.0
PSMB1 -7998.0 -12452.0
PSMB10 1546.0 -12645.0
PSMB11 -7675.0 461.0
PSMB2 -15087.0 -14324.0
PSMB3 -2943.0 -16574.0
PSMB4 -3092.0 -17193.0
PSMB5 -2173.0 -13304.0
PSMB6 -1270.0 -15778.0
PSMB7 1688.0 1166.0
PSMB8 251.0 -10098.0
PSMB9 -4477.0 -14712.0
PSMC1 -2414.0 -13145.0
PSMC2 -315.0 -2310.0
PSMC3 -7461.0 -17123.0
PSMC3IP -2516.0 -17127.0
PSMC4 459.0 -4407.0
PSMC5 -9725.0 -12293.0
PSMC6 -7301.0 332.0
PSMD1 -15755.0 -15264.0
PSMD11 -6796.0 -15996.0
PSMD12 -13229.0 -1837.0
PSMD13 -9340.0 -12191.0
PSMD14 -9752.0 -14404.0
PSMD2 -5101.0 -4469.0
PSMD3 -6030.0 -12489.0
PSMD4 -6049.0 -14518.0
PSMD5 2564.0 -8724.0
PSMD6 -5979.0 -12939.0
PSMD7 -12233.0 -5710.0
PSMD8 -9781.0 -13888.0
PSMD9 -11408.0 -10645.0
PSME1 -9760.0 -16962.0
PSME2 67.0 -15711.0
PSME3 -4965.0 -13719.0
PSME4 -13130.0 -13058.0
PSMF1 -12443.0 -3758.0
PTK6 -14982.0 -2393.0
PTTG1 -3508.0 -13806.0
RAB1A -11800.0 -11205.0
RAB1B -11811.0 -13124.0
RAB2A -15533.0 -5166.0
RAB8A -2437.0 -12675.0
RAD1 -10349.0 -12579.0
RAD17 -9131.5 -14142.0
RAD21 -13034.0 -4206.0
RAD50 -5291.0 -7668.0
RAD51 -1993.0 -15382.0
RAD51C -9057.0 93.0
RAD9A -13056.0 -11198.0
RAD9B -14660.0 -6250.0
RAE1 -10699.0 -7730.0
RAN -10662.0 -16269.0
RANBP2 -8430.0 -15721.0
RANGAP1 -7181.0 -12265.0
RB1 -9395.0 -7632.0
RBBP4 -9690.0 -15408.0
RBBP8 -12465.0 -15065.0
RBL1 823.0 -5072.0
RBL2 -7303.0 -11548.0
RBX1 -6001.0 -10254.0
RCC1 -308.0 -2368.0
RCC2 -5320.0 -5307.0
REC8 -2420.0 -7906.0
RFC1 -11317.0 -9485.0
RFC2 -11390.0 -13410.0
RFC3 1547.0 -8638.0
RFC4 -12661.0 -13699.0
RFC5 -3459.0 -7830.0
RHNO1 -10225.0 -9607.0
RMI1 -14153.0 -11854.0
RMI2 -8312.0 -8455.0
RNF168 -3627.0 -5998.0
RNF8 -13451.0 -7725.0
RPA1 1482.0 -2054.0
RPA2 -6976.0 -8172.0
RPA3 -13260.0 -8291.0
RPS27 1722.0 -11381.0
RPS27A -11481.0 -2147.0
RRM2 -10442.0 -8505.0
RSF1 -2376.0 -12694.0
RTEL1 -10741.0 -5615.0
RUVBL1 -10977.0 -7680.0
RUVBL2 139.0 -15895.0
SDCCAG8 -4661.0 -3633.0
SEC13 -8604.0 -10471.0
SEH1L -8901.0 -14935.0
SEM1 -1388.0 -14801.0
SET -8737.0 -6532.0
SFI1 -12444.0 -11569.0
SFN -14353.0 255.0
SGO1 -4675.0 -4366.0
SGO2 -1842.0 -8446.0
SHQ1 -13781.0 -4904.0
SIRT2 -6884.0 -9850.0
SKA1 -6465.0 -16444.0
SKA2 -5163.0 -5832.0
SKP1 -9613.0 -15257.0
SKP2 -3788.0 -6780.0
SMARCA5 -9298.0 -13297.0
SMC1B -13280.0 -9458.0
SMC2 -6739.0 -8249.0
SMC3 -14879.0 -16404.0
SMC4 -14508.0 -9211.0
SPAST -15874.0 -9503.0
SPC24 -11068.0 -15981.0
SPC25 -3265.0 -2763.0
SPDL1 -5198.0 -9012.0
SPO11 -4160.0 1419.0
SRC -8945.0 -2260.0
SSNA1 -5964.0 -8575.0
STAG1 -4192.0 -10829.0
STAG3 -14493.0 -6821.0
STN1 -7832.0 -7469.0
SUMO1 -32.0 -9758.0
SUN1 175.0 -3415.0
SUN2 -10997.0 -11799.0
SYCE1 -324.0 -1251.0
SYCE2 -7948.0 -12433.0
SYCE3 -16084.0 -14745.0
SYCP1 -1668.0 1385.0
SYCP2 1678.0 -10898.0
SYCP3 859.0 -3442.0
SYNE1 -4783.0 -10518.0
SYNE2 -2034.0 -8852.0
TAOK1 -12592.0 -8943.0
TEN1 -11072.0 -10435.0
TERF1 -12674.0 -13108.0
TERF2 -13771.0 -2138.0
TERF2IP -9680.0 -15559.0
TERT -1364.0 -2257.0
TEX12 -575.0 -5742.0
TEX15 -16459.0 -14063.0
TFDP1 -507.0 -45.0
TFDP2 -14013.0 -2679.0
TINF2 -8141.0 -14245.0
TK1 -4756.0 -10019.0
TMPO -15535.0 -8262.0
TNPO1 -12905.0 -8329.0
TOP2A -4473.0 -4314.0
TOP3A -7766.0 -4898.0
TOPBP1 -14077.0 -16364.0
TP53 -3878.0 -8153.0
TP53BP1 -461.0 -10402.0
TPR -12390.0 -14677.0
TPX2 -11984.0 308.0
TUBA1A -2200.0 -6514.0
TUBA1B -14029.0 -17230.0
TUBA1C -3384.0 -9518.0
TUBA3C -2572.0 1353.0
TUBA3D 667.0 1328.0
TUBA3E -557.0 1710.0
TUBA4A -14192.0 -8929.0
TUBA4B -12730.0 -11735.0
TUBA8 -10422.0 -5063.0
TUBAL3 -1441.0 974.0
TUBB -4832.0 -14732.0
TUBB1 474.0 -2704.0
TUBB2A -9611.0 -15207.0
TUBB2B -3861.0 -15169.0
TUBB3 -8126.0 -15236.0
TUBB4A -7628.0 279.0
TUBB4B -1709.0 -4047.0
TUBB6 -10077.0 -1707.0
TUBB8 -5845.0 1599.0
TUBG1 -16375.0 -14891.0
TUBG2 -2182.0 -9317.0
TUBGCP2 -2326.0 -864.0
TUBGCP3 -11364.0 -8086.0
TUBGCP4 -14320.0 -6397.0
TUBGCP5 -5996.0 -13306.0
TUBGCP6 -5866.0 -11053.0
TYMS -9594.0 -16610.0
UBA52 -10894.0 -4996.0
UBB -12784.0 -8060.0
UBC -11566.0 -692.0
UBE2C -14095.0 -14424.0
UBE2D1 -9905.0 -15085.0
UBE2E1 -7722.0 -8346.0
UBE2I -10552.0 -5939.0
UBE2N -9458.0 -16754.0
UBE2S -10702.0 -8077.0
UBE2V2 -16133.0 -1676.0
UIMC1 -9235.0 -8424.0
USO1 -8214.0 -10133.0
VPS4A -6364.0 -13269.0
VRK1 -14545.0 -13800.0
VRK2 -11405.0 -3325.0
WAPL -15001.0 -14312.0
WEE1 -13550.0 -14529.0
WRAP53 -3242.0 -8585.0
WRN -10141.5 -6355.0
XPO1 -11418.0 -13329.0
YWHAB -12447.0 -2244.0
YWHAE -7622.0 -13250.0
YWHAG -5540.0 -4226.0
YWHAH -15299.0 -11577.0
YWHAQ -14845.0 -8678.0
YWHAZ -11791.0 -10782.0
ZNF385A -10615.0 -5596.0
ZW10 -1493.0 -10411.0
ZWILCH -15096.0 -2173.0
ZWINT -11659.0 -15238.0



REACTOME_CELLULAR_RESPONSES_TO_STIMULI

REACTOME_CELLULAR_RESPONSES_TO_STIMULI
metric value
setSize 781
pMANOVA 1.05e-12
p.adjustMANOVA 1.72e-10
s.dist 0.174
s.Estill -0.105
s.Novakovic -0.139
p.Estill 5.86e-07
p.Novakovic 4.32e-11




Top 20 genes
Gene Estill Novakovic
CLEC1B -16327 -17172
PRDX5 -15848 -17210
E2F1 -16127 -16773
RPL36 -15878 -16971
CDKN2B -15666 -17173
LAMTOR2 -15827 -16936
MAP1LC3B -15884 -16669
ATP6V1E1 -15701 -16740
NUP37 -15153 -17285
H3C12 -15164 -17158
VENTX -15063 -17017
NUP153 -14779 -17257
KICS2 -15615 -16083
MIOS -15826 -15769
CDKN2D -14848 -16781
CASTOR2 -14444 -17061
H1-2 -14270 -17244
GCLM -15437 -15935
CBX8 -15191 -16149
PSMA7 -15238 -16097

Click HERE to show all gene set members

All member genes
Estill Novakovic
AAAS -5233.0 -3868.0
ABCC1 -1425.0 -1481.0
ACADVL -3105.0 -8275.0
ACD -6267.0 -6892.5
ACTR10 -7672.0 -17095.0
ACTR1A -10774.0 -9995.0
ADD1 -6500.0 -10558.0
AGO1 -747.0 -11588.0
AGO3 -13810.0 -14109.0
AGO4 -10031.0 -8287.0
AJUBA -4874.0 -10340.0
AKT1 -6145.0 -2432.0
AKT1S1 -12045.0 -8582.0
AKT2 -12142.0 -6370.0
AKT3 -835.0 -5588.0
ALB -7500.0 -15417.0
ANAPC1 -2324.0 -5744.0
ANAPC10 -11343.0 -5816.0
ANAPC11 -15553.0 -3569.0
ANAPC15 -5573.0 -1354.0
ANAPC16 -3464.0 -3219.0
ANAPC2 -8367.0 -1213.0
ANAPC4 -11051.0 -6188.0
ANAPC5 -7613.0 -11860.0
ANAPC7 -6389.0 -4274.0
APOA1 -7264.0 -5044.0
APOB 340.0 -10566.0
AQP8 -3154.0 314.0
ARFGAP1 -15805.0 -11740.0
ARNT -12079.0 -1076.0
ASF1A 2394.0 -11132.0
ASNS -12523.0 -3499.0
ATF2 -6207.0 -6194.0
ATF3 -3655.0 -7904.0
ATF4 -2615.0 -14466.0
ATF5 -4985.0 -6894.0
ATF6 1575.0 -6518.0
ATM -10666.0 -3054.0
ATOX1 -10773.0 -11190.0
ATP6V0B -13617.0 -11086.0
ATP6V0C -13656.0 -9496.0
ATP6V0D1 -3181.0 -14043.0
ATP6V0D2 1818.0 477.0
ATP6V0E1 51.0 -7886.0
ATP6V0E2 -14863.0 -13012.0
ATP6V1A -14998.0 -3702.0
ATP6V1B1 -9405.0 -14749.0
ATP6V1B2 -12353.0 -5339.0
ATP6V1C1 -2923.0 -8310.0
ATP6V1C2 -5110.0 -6736.0
ATP6V1D -832.0 -10071.0
ATP6V1E1 -15701.0 -16740.0
ATP6V1E2 1998.0 1394.0
ATP6V1F -4404.0 1153.0
ATP6V1G1 -4860.0 -8958.0
ATP6V1G2 -11779.0 -10251.0
ATP6V1H -12053.0 -13165.0
ATR -5921.0 -15232.0
BACH1 -12455.0 -5264.0
BAG1 -9498.0 -11671.0
BAG2 -14002.0 -1289.0
BAG3 -6016.0 -9128.0
BAG4 -13479.0 -13711.0
BAG5 -9238.0 -15795.0
BLVRA -9126.0 -12717.0
BLVRB -15828.0 -14691.0
BMAL1 -6327.0 -3866.0
BMI1 -16012.0 -13112.0
BMT2 -9249.0 -919.0
BRCA1 2021.0 628.0
BTRC -8741.0 -7184.0
CA9 -2562.0 -12346.0
CABIN1 -10378.0 -6522.0
CALR -6453.0 -8798.0
CAMK2A -10797.0 -6876.0
CAMK2B -10282.0 -6791.0
CAMK2D -2540.0 -11657.0
CAMK2G -2502.0 -899.0
CAPZA1 -3504.0 -10215.0
CAPZA2 -13595.0 -14422.0
CAPZA3 -292.0 571.0
CAPZB 383.0 -902.0
CARM1 -7610.0 -7767.0
CASTOR1 -9041.0 -9645.0
CASTOR2 -14444.0 -17061.0
CAT -11204.0 -1805.0
CBX2 -14491.0 -6483.0
CBX4 -7580.0 -13492.0
CBX6 -11898.0 -11046.0
CBX8 -15191.0 -16149.0
CCAR2 -8201.0 -9591.0
CCL2 747.0 -6393.0
CCNA1 -11907.0 -12984.0
CCNA2 -6087.0 -16501.0
CCNE1 -14226.0 -16873.0
CCNE2 -10192.0 -8331.0
CCS -13484.0 -13131.0
CDC16 -3120.0 -6337.0
CDC23 -4732.0 -5268.0
CDC26 -5432.0 -868.0
CDC27 -8038.0 -11129.0
CDK2 -241.0 -10000.0
CDK4 -12590.0 -14349.0
CDK6 -7466.0 -5435.0
CDKN1A -7625.0 -12022.0
CDKN1B -15950.0 -12998.0
CDKN2A -13143.0 -1475.0
CDKN2B -15666.0 -17173.0
CDKN2C -9649.0 -15409.0
CDKN2D -14848.0 -16781.0
CEBPB -15578.0 -14184.0
CEBPG -12298.0 -12515.0
CHAC1 -13308.0 -12832.0
CHD9 -4554.0 -11622.0
CITED2 -15475.0 -11600.0
CLEC1B -16327.0 -17172.0
CLOCK -9086.0 -13762.0
COX11 -10902.0 -15866.0
COX14 -15402.0 -15339.0
COX16 -10443.0 134.0
COX18 -14154.0 -9252.0
COX19 -8594.0 -5715.0
COX20 -9445.0 -15182.0
COX4I1 -8427.0 -17276.0
COX5A -12320.0 -13007.0
COX5B -14297.0 -12160.0
COX6A1 -2855.0 -15071.0
COX6B1 -4301.0 -9406.0
COX6C -6273.0 -2535.0
COX7A2L -12857.0 -12460.0
COX7C -11305.0 -12041.0
COX8A 1645.0 -16534.0
CREB1 -16059.0 -6298.0
CREB3 -6916.0 -14007.0
CREB3L1 -5951.0 -5286.0
CREB3L2 -1629.0 -5417.0
CREB3L3 -15583.0 -774.0
CREB3L4 -7561.0 -8583.0
CREBBP 522.0 -5671.0
CREBRF -13335.0 -14510.0
CRTC1 -7099.0 -6330.0
CRTC2 -12405.0 -9878.0
CRTC3 -1334.0 -7128.0
CRYAB -16286.0 -5258.0
CRYBA4 -9161.0 -476.0
CSNK2A1 -10932.0 -4915.0
CSNK2A2 -15748.0 -7535.0
CSNK2B -367.0 -14595.0
CSRP1 -12930.0 -11484.0
CTDSP2 -7483.0 -9450.0
CUL1 -2215.0 449.0
CUL2 -3906.0 -4879.0
CUL3 -14992.0 -6223.0
CUL7 -3055.0 -10083.0
CXXC1 -3614.0 -400.0
CYBA -9733.0 -9459.0
CYCS -13068.0 -11301.0
DCP2 -4550.0 -6209.0
DCSTAMP 1590.0 -3657.0
DCTN1 69.0 -10034.0
DCTN2 -6153.0 -1119.0
DCTN3 -12480.0 -10976.0
DCTN4 -1097.0 -8901.0
DCTN5 -10444.0 -16514.0
DCTN6 -103.0 -8210.0
DDIT3 -14204.0 -11300.0
DDX11 -8801.0 -1159.0
DEDD2 -3005.0 -8403.0
DEPDC5 -9902.0 -1585.0
DIS3 -2692.0 -3659.0
DNAJA1 -9939.0 203.0
DNAJA2 -10748.0 -10309.0
DNAJA4 -6779.0 -2380.0
DNAJB1 -13644.0 -6670.0
DNAJB11 -10976.0 -10933.0
DNAJB6 -1123.0 -4026.0
DNAJB9 -14617.5 -9261.0
DNAJC2 -4626.0 135.0
DNAJC3 -7188.0 -13765.0
DNAJC7 -3475.0 -13322.0
DPP3 -15648.0 -6513.0
DYNC1H1 48.0 -3145.0
DYNC1I1 -7317.0 -6097.0
DYNC1I2 1732.0 -12829.0
DYNC1LI1 -11159.0 -13138.0
DYNC1LI2 -12760.0 -7326.0
DYNLL1 -11160.0 -14050.0
DYNLL2 -13828.0 -13633.0
E2F1 -16127.0 -16773.0
E2F2 -13924.0 -7662.0
E2F3 -4245.0 -3475.0
EDEM1 -12366.0 -14410.0
EED -10652.0 -4813.0
EEF1A1 -7263.0 -14577.0
EGLN1 -10537.0 -8992.0
EGLN2 -4347.0 -3813.0
EGLN3 -12985.0 -16078.0
EHMT1 708.0 -1487.0
EHMT2 -2283.0 -2489.0
EIF2AK1 -8780.0 -8924.0
EIF2AK3 -4106.0 -8742.0
EIF2AK4 -3557.0 -15338.0
EIF2S1 -1610.0 -12288.0
EIF2S2 -9285.0 -8900.0
ELOB -10647.0 -14069.0
ELOC -661.0 -10616.0
EP300 -1567.0 -10732.0
EP400 1406.0 -2193.0
EPAS1 -2485.0 -8281.0
EPO -15622.0 -287.0
ERF -10954.0 -16611.0
ERN1 -4486.0 -2485.0
ERO1A -13114.0 -12893.0
ETS1 -4405.0 -5539.0
ETS2 -5322.0 -1189.0
EXOSC1 -11535.0 -12332.0
EXOSC2 -8230.0 -8207.0
EXOSC3 -3581.0 -16081.0
EXOSC4 -6412.0 -13941.0
EXOSC5 -14082.0 -9766.0
EXOSC6 -12471.0 -16303.0
EXOSC7 -9065.0 -6973.0
EXOSC8 -11683.0 -3776.0
EXOSC9 -8456.0 -7477.0
EXTL1 -862.0 -7039.0
EXTL2 -11235.0 -5478.0
EXTL3 -26.0 -7941.0
EZH2 -5256.0 -15114.0
FABP1 -2026.0 -7793.0
FAU -8361.0 -15762.0
FBXL17 -10487.0 -11540.0
FKBP14 -7157.0 -7133.0
FKBP4 -11397.0 -14655.0
FKBP5 -6337.0 -8804.0
FLCN -1896.0 -6564.0
FNIP1 -10727.0 -13964.0
FNIP2 -10595.0 -4951.0
FOS -6751.0 -11648.0
FZR1 -7455.0 -2900.0
GCLC -13204.0 -16087.0
GCLM -15437.0 -15935.0
GCN1 -14340.0 -6824.0
GFPT1 -6998.0 -12035.0
GML -7798.0 173.0
GOSR2 -982.0 -8260.0
GPX1 -12714.0 -15674.0
GPX2 848.0 -12900.0
GPX3 -1115.0 -10926.0
GPX5 1109.0 -7449.0
GPX6 1003.0 613.0
GPX7 -10108.0 -16921.0
GPX8 1308.0 971.0
GRB10 -454.0 -7601.0
GSK3A -12174.0 -10805.0
GSK3B -13275.0 -5625.0
GSR 362.0 -15617.0
GSTA1 -1904.0 1407.0
GSTA3 440.0 1017.0
GSTP1 -3456.0 -5265.0
H1-0 -1991.0 -16068.0
H1-1 2480.0 -8225.0
H1-2 -14270.0 -17244.0
H1-3 -6861.0 -1821.0
H1-4 -14299.0 -16576.0
H1-5 -16423.0 -7474.0
H2AC14 -740.0 -6291.0
H2AC18 -10109.5 -16821.5
H2AC19 -10109.5 -16821.5
H2AC20 -9365.0 -421.0
H2AC4 -8682.0 -7652.0
H2AC6 -3772.0 -14402.0
H2AC7 -10309.0 -3529.5
H2AC8 -15265.0 -12472.0
H2AJ -360.0 -16792.0
H2AX -13329.0 -16764.0
H2AZ1 -10477.0 -10825.0
H2AZ2 -15177.0 -12968.0
H2BC1 930.5 1414.0
H2BC10 -12140.0 -5784.0
H2BC11 -4716.0 -15808.0
H2BC12 -3961.0 -14793.0
H2BC13 -11400.0 761.0
H2BC14 -1609.0 -8267.0
H2BC15 -2744.0 -168.0
H2BC17 -16322.0 -3166.0
H2BC21 -8996.0 -6316.0
H2BC26 -11379.0 -16861.0
H2BC3 -15205.0 -10594.0
H2BC4 -10641.0 -8955.0
H2BC5 -9533.0 315.0
H2BC6 -15206.0 266.0
H2BC7 -11776.0 -3529.5
H2BC8 -15228.0 -8541.0
H2BC9 -9951.5 -12902.5
H3-3A -13934.0 -14636.0
H3-3B -9143.0 -13971.0
H3-4 1657.0 1580.0
H3C1 -9230.0 -14629.0
H3C10 -3065.0 -374.0
H3C11 -7068.0 -13728.0
H3C12 -15164.0 -17158.0
H3C13 -4294.0 -15204.0
H3C2 -15289.0 -11553.0
H3C3 -6133.0 -14272.0
H3C4 -9971.0 -5667.0
H3C6 371.0 -17250.0
H3C7 -9951.5 -12902.5
H3C8 -15918.0 -12729.0
H4C1 -14459.0 -9617.0
H4C11 854.0 -16001.0
H4C12 -2120.0 -5312.0
H4C13 -334.0 -15402.0
H4C16 -7238.0 -8548.0
H4C2 -7763.0 -2343.0
H4C3 -5978.0 -7968.0
H4C4 -850.0 -16161.0
H4C5 -1971.0 -1886.0
H4C6 -9232.0 -16384.0
H4C8 -3484.0 -14606.0
H4C9 -10105.0 -17149.0
HBA1 -10386.0 -15637.0
HBA2 -11386.0 1304.0
HBB -4804.0 -13305.0
HDAC3 -13458.0 -14340.0
HDGF -8751.0 -13627.0
HELZ2 -12220.0 -9175.0
HERPUD1 -15344.0 -15832.0
HIF1A -8609.0 -13639.0
HIF1AN -3629.0 -14335.0
HIF3A -4986.0 -4098.0
HIGD1A -15951.0 -13563.0
HIKESHI -2505.0 -10932.0
HIRA -16221.0 -12518.0
HM13 -5435.0 -3920.0
HMGA1 -14283.0 -16529.0
HMGA2 -3036.0 -961.0
HMOX1 -10317.0 -13400.0
HMOX2 -6009.0 -9776.0
HSBP1 -5068.0 -12211.0
HSF1 -8950.0 -2101.0
HSP90AA1 -13375.0 -9820.0
HSP90AB1 -11098.0 -973.0
HSP90B1 -6959.0 -7971.0
HSPA12A -6400.0 -1763.0
HSPA12B -10059.0 -9818.0
HSPA13 -5008.0 -14363.0
HSPA14 -13561.0 -992.0
HSPA1A -11140.0 -12542.0
HSPA1B -2929.0 -13838.0
HSPA1L -2864.0 -2737.0
HSPA2 -1902.0 -9544.0
HSPA4 -11273.0 -5093.0
HSPA4L -10757.0 -14030.0
HSPA5 -5515.0 -5492.0
HSPA6 -2364.0 -6030.0
HSPA8 -7258.0 -2055.0
HSPA9 -8922.0 -16233.0
HSPB1 -15704.0 -9010.0
HSPB2 -16190.0 -3173.0
HSPB8 -12520.0 -5287.0
HSPH1 -9325.0 -13420.0
HYOU1 -10079.0 -8435.0
ID1 -15915.0 -15266.0
IDH1 -4652.0 -8283.0
IGFBP1 -10627.0 -13509.0
IGFBP7 -4747.0 -7716.0
IL1A 1465.0 -7341.0
IL6 -14125.0 271.0
IMPACT -12435.0 -12470.0
ITFG2 -4230.0 278.0
JUN -12813.0 -12417.0
KAT5 -7750.0 -6812.0
KDELR3 -15520.0 -7650.0
KDM6B -2275.0 -11613.0
KEAP1 -9462.0 -12683.0
KHSRP -5753.0 705.0
KICS2 -15615.0 -16083.0
KLHDC3 -16020.0 -13749.0
KPTN -7371.0 -13551.0
LAMTOR1 -4373.0 -1485.0
LAMTOR2 -15827.0 -16936.0
LAMTOR3 -9742.0 -9546.0
LAMTOR4 -3862.0 -10879.0
LAMTOR5 -5629.0 -15481.0
LIMD1 -8462.0 -4722.0
LMNA -8291.0 -4922.0
LMNB1 -12895.0 -9972.0
LRPPRC 1909.0 -6137.0
LY96 2462.0 1340.0
MAFG -14062.0 -4184.0
MAFK -8503.0 -2558.0
MAP1LC3B -15884.0 -16669.0
MAP2K3 -14079.0 -2543.0
MAP2K4 -10277.0 -14637.0
MAP2K6 -1705.0 -7317.0
MAP2K7 -10724.0 -4933.0
MAP3K5 -10494.0 -7836.0
MAP4K4 -607.0 -9441.0
MAPK1 -9762.0 -6238.0
MAPK10 -777.0 -1880.0
MAPK11 -5152.0 -7765.0
MAPK14 -13326.0 -12144.0
MAPK3 -14286.0 -1298.0
MAPK7 -12512.0 -15733.0
MAPK8 -10354.0 -13170.0
MAPK9 -14622.0 -15345.0
MAPKAPK2 -4999.0 -998.0
MAPKAPK3 297.0 -8460.0
MAPKAPK5 -15076.0 -14461.0
MBTPS1 -9510.0 -5159.0
MDM2 -10651.0 113.0
MDM4 -1979.0 -12057.0
ME1 -1863.0 -14750.0
MED1 352.0 -15119.0
MEF2C -3644.0 -5180.0
MEF2D -2497.0 -565.0
MINK1 -5463.0 -7330.0
MIOS -15826.0 -15769.0
MIR24-1 1548.0 141.0
MIR24-2 -13601.0 -6025.0
MLST8 -15381.0 -13231.0
MOV10 -9064.0 -10123.0
MRE11 -5819.0 -3826.0
MRPL18 -4819.0 -14508.0
MT1A -12062.0 -6961.0
MT1B -12608.0 -2180.0
MT1E -6788.0 -16229.0
MT1F -13302.0 -8815.0
MT1G -11302.0 249.0
MT1H -4709.0 -4855.0
MT1M -14427.0 -10833.0
MT1X -3467.0 -12583.0
MT2A -12187.0 -16867.0
MT3 -12369.0 -9730.0
MT4 -5650.0 38.0
MTF1 -7739.0 -11399.0
MTOR 819.0 -8409.0
MUL1 -8575.0 -11873.0
MYC -9179.0 -13967.0
MYDGF -11615.0 -10661.0
NBN -14657.0 -15359.0
NCF1 -6811.0 1426.0
NCF2 2178.0 -3018.0
NCF4 -7756.0 -4433.0
NCOA1 -27.0 -2555.0
NCOA2 -8180.0 -8641.0
NCOA6 -6671.0 -7768.0
NCOR1 -12162.0 -4890.0
NCOR2 -2181.0 -536.0
NDC1 -11478.0 -8778.0
NDUFA4 -7632.0 -13255.0
NFE2L2 -7505.0 -15009.0
NFKB1 -8018.0 -7183.0
NFYA -8234.0 -3027.0
NFYB -9099.0 -9990.0
NFYC 112.0 -4566.0
NLRP3 -2300.0 205.0
NOTCH1 -3873.0 -3160.0
NOX4 -13590.0 -10753.0
NOX5 -1215.0 -6702.0
NPAS2 -91.0 -2768.0
NPLOC4 -6167.0 -2163.0
NPRL2 -11454.0 -11257.0
NPRL3 -2853.0 -4929.0
NQO1 -13576.0 -5358.0
NR1D1 -9261.0 -4892.0
NR3C1 -11555.0 -12296.0
NR3C2 -13381.0 -5529.0
NRIP1 -13272.0 -13746.0
NUDT2 -8004.0 -4694.0
NUP107 -7236.0 -8001.0
NUP133 -2470.0 -9143.0
NUP153 -14779.0 -17257.0
NUP155 -12129.0 -15214.0
NUP160 -11625.0 -12148.0
NUP188 -7877.0 -15187.0
NUP205 -7637.0 -436.0
NUP210 -10939.0 -191.0
NUP214 -13610.0 -5777.0
NUP35 -1428.0 -7296.0
NUP37 -15153.0 -17285.0
NUP42 -8725.0 -15797.0
NUP43 -6734.0 -13552.0
NUP50 -14109.0 -5828.0
NUP54 -12929.0 -7747.0
NUP58 -9205.0 -15350.0
NUP62 -3466.0 -2332.0
NUP85 -4129.0 -11356.0
NUP88 -7189.0 -10830.0
NUP93 -3140.0 -9015.0
NUP98 -8145.0 -10870.0
P4HB -7689.0 -1373.0
PALB2 -12055.0 -14494.0
PARN -1748.0 -10005.0
PDIA5 -8739.0 -8276.0
PDIA6 -11142.0 -4172.0
PGD -13476.0 -12697.0
PGR -11785.0 9.0
PHC1 -12792.0 -12915.0
PHC2 -2255.0 -5791.0
PHC3 -6951.0 -7813.0
PLA2G4B -15029.0 -9422.0
POM121 -13119.0 -11642.0
POM121C -3009.0 -6792.0
POT1 824.0 -7508.0
PPARA 321.0 -4843.0
PPARGC1A -2243.0 44.0
PPP1R15A -12508.0 997.0
PPP2R5B -6416.0 -16175.0
PRDX1 -6218.0 336.0
PRDX2 -14231.0 -13787.0
PRDX3 -9712.0 -7319.0
PRDX5 -15848.0 -17210.0
PRDX6 -10045.0 -14086.0
PREB 101.0 -11463.0
PRKCD -13406.0 -5373.0
PSMA1 -8781.0 -2177.0
PSMA2 -7391.0 -13190.0
PSMA3 -543.0 -12585.0
PSMA4 -1489.0 -11130.0
PSMA5 -5612.0 -12086.0
PSMA6 -5453.0 -7068.0
PSMA7 -15238.0 -16097.0
PSMA8 -12998.0 1341.0
PSMB1 -7998.0 -12452.0
PSMB10 1546.0 -12645.0
PSMB11 -7675.0 461.0
PSMB2 -15087.0 -14324.0
PSMB3 -2943.0 -16574.0
PSMB4 -3092.0 -17193.0
PSMB5 -2173.0 -13304.0
PSMB6 -1270.0 -15778.0
PSMB7 1688.0 1166.0
PSMB8 251.0 -10098.0
PSMB9 -4477.0 -14712.0
PSMC1 -2414.0 -13145.0
PSMC2 -315.0 -2310.0
PSMC3 -7461.0 -17123.0
PSMC4 459.0 -4407.0
PSMC5 -9725.0 -12293.0
PSMC6 -7301.0 332.0
PSMD1 -15755.0 -15264.0
PSMD11 -6796.0 -15996.0
PSMD12 -13229.0 -1837.0
PSMD13 -9340.0 -12191.0
PSMD14 -9752.0 -14404.0
PSMD2 -5101.0 -4469.0
PSMD3 -6030.0 -12489.0
PSMD4 -6049.0 -14518.0
PSMD5 2564.0 -8724.0
PSMD6 -5979.0 -12939.0
PSMD7 -12233.0 -5710.0
PSMD8 -9781.0 -13888.0
PSMD9 -11408.0 -10645.0
PSME1 -9760.0 -16962.0
PSME2 67.0 -15711.0
PSME3 -4965.0 -13719.0
PSME4 -13130.0 -13058.0
PSMF1 -12443.0 -3758.0
PTGES3 -8554.0 -7663.0
PTK6 -14982.0 -2393.0
RAD50 -5291.0 -7668.0
RAE1 -10699.0 -7730.0
RAI1 -8222.0 -3553.0
RANBP2 -8430.0 -15721.0
RB1 -9395.0 -7632.0
RBBP4 -9690.0 -15408.0
RBX1 -6001.0 -10254.0
RELA -15610.0 -9300.0
RHEB -4914.0 -7995.0
RING1 -5983.0 -3121.0
RLN1 2361.0 1606.0
RNF2 -3565.0 -967.0
RORA -2327.0 -6546.0
RPA1 1482.0 -2054.0
RPA2 -6976.0 -8172.0
RPA3 -13260.0 -8291.0
RPL10A -4327.0 -16688.0
RPL10L -4672.0 1242.0
RPL11 -7730.0 -11362.0
RPL12 -1818.0 -7657.0
RPL13 -13096.0 -17048.0
RPL13A -1938.5 -10955.5
RPL14 -8334.0 -15519.0
RPL15 -13598.0 -15972.0
RPL17 -4720.0 -15113.0
RPL18 -6084.0 -16405.0
RPL18A -13854.0 -12314.0
RPL19 -9925.0 -950.0
RPL21 -9899.5 -13500.5
RPL22 -2661.0 -13474.0
RPL22L1 -2679.0 -16975.0
RPL23 -3278.0 -4599.0
RPL23A -8489.0 -13877.0
RPL24 813.0 329.0
RPL26 -7851.0 -14206.0
RPL26L1 -4159.0 -17223.0
RPL27 -10972.0 -14660.0
RPL27A -11040.0 -16640.0
RPL28 -7060.0 -12491.0
RPL29 -6766.0 -14551.0
RPL3 -4433.0 -6744.0
RPL30 -3473.0 -13276.0
RPL31 160.0 -9807.0
RPL32 -8290.0 -7245.0
RPL34 -3639.0 913.0
RPL35 -12031.0 -16424.0
RPL35A -563.0 -483.0
RPL36 -15878.0 -16971.0
RPL36AL -12581.0 -15545.0
RPL37 -5636.0 -11980.0
RPL37A -8914.0 -12749.0
RPL38 -3414.0 -3066.0
RPL39L -2329.0 -16531.0
RPL3L -13013.0 328.0
RPL4 -7696.0 199.0
RPL41 -8377.0 -15742.0
RPL5 1478.0 -13656.0
RPL6 718.0 -2953.0
RPL7 -11616.0 -15741.0
RPL7A -11184.0 -3709.0
RPL8 -16023.0 -13701.0
RPL9 -4066.0 -291.0
RPLP0 -7445.0 -14511.0
RPLP1 -5049.0 -3663.0
RPLP2 -14824.0 -14743.0
RPS10 -11363.0 -14602.0
RPS11 -12666.0 -8009.0
RPS12 -5554.0 -5380.0
RPS13 541.0 -12870.0
RPS14 -14985.0 -576.0
RPS15 -11816.0 -15841.0
RPS15A 1563.0 -10896.0
RPS16 -12775.0 -13973.0
RPS17 363.0 -17286.0
RPS18 -5492.0 -6509.0
RPS19 -4848.0 -463.0
RPS19BP1 -3579.0 -14527.0
RPS2 -8403.0 -13161.0
RPS20 -9963.0 -9064.0
RPS21 -14247.0 -15846.0
RPS23 -4455.0 -10331.0
RPS24 1255.0 -3232.0
RPS25 -2544.0 -11699.0
RPS26 802.0 -7841.0
RPS27 1722.0 -11381.0
RPS27A -11481.0 -2147.0
RPS27L -9482.0 -16569.0
RPS28 -12352.0 -15277.0
RPS29 -8298.0 -16523.0
RPS3 1404.0 -10369.0
RPS3A -10279.0 -15494.0
RPS5 -15070.0 -15693.0
RPS6 -16407.0 -6799.0
RPS6KA1 -11256.0 -1514.0
RPS6KA2 -1031.0 -2634.0
RPS7 -3124.0 -12481.0
RPS8 -9073.0 -1281.0
RPS9 -11982.0 -623.0
RPSA -4693.0 -3295.0
RPTOR -686.0 -708.0
RRAGA -1430.0 -17105.0
RRAGC -5607.0 -14388.0
RRAGD -7560.0 -10498.0
RXRA -6530.0 -1218.0
SCMH1 -4232.0 -9009.0
SCO1 -13917.0 -15055.0
SCO2 -15098.0 -13166.0
SEC13 -8604.0 -10471.0
SEC31A -15136.0 -11060.0
SEH1L -8901.0 -14935.0
SEM1 -1388.0 -14801.0
SERP1 -14406.0 -16814.0
SERPINH1 -6156.0 -1876.0
SESN1 -14137.0 -12007.0
SESN2 -7923.0 -16070.0
SH3BP4 -1626.0 -3701.0
SHC1 -5102.0 -9832.0
SIN3A -7719.0 -12217.0
SIN3B -2163.0 -3188.0
SIRT1 -16216.0 -14094.0
SKP1 -9613.0 -15257.0
SKP2 -3788.0 -6780.0
SLC38A9 -11447.0 -16016.0
SLC46A1 -2057.0 -15082.0
SLC7A11 1900.0 -8846.0
SMARCD3 -14168.0 -12535.0
SNCB -14155.0 -2688.0
SOD1 -13337.0 -7622.0
SOD2 -15456.0 -12662.0
SOD3 -3157.0 -7415.0
SP1 -6339.0 -10024.0
SQSTM1 -10407.0 -9268.0
SRPRA -14147.0 -16039.0
SRPRB -5891.0 -15710.0
SRXN1 -12919.0 -11845.0
SSR1 -4792.0 -8523.0
ST13 -14629.0 -16591.0
STAP2 -14877.0 -1860.0
STAT3 -12230.0 -8998.0
STIP1 -7852.0 -9558.0
SULT1A3 571.5 -6784.5
SURF1 -15514.0 -12618.0
SUZ12 -12029.0 -10907.0
SYVN1 -12854.0 -11547.0
SZT2 -9029.0 -11372.0
TACO1 -1219.0 -3712.0
TALDO1 -8283.0 -12960.0
TATDN2 -14633.0 -15965.0
TBL1XR1 -10122.0 -9554.0
TCIRG1 -12084.0 -2207.0
TERF1 -12674.0 -13108.0
TERF2 -13771.0 -2138.0
TERF2IP -9680.0 -15559.0
TFDP1 -507.0 -45.0
TFDP2 -14013.0 -2679.0
TGS1 -7408.0 -16254.0
TINF2 -8141.0 -14245.0
TKT -14835.0 -4544.0
TLN1 -8119.0 -6902.0
TLR4 -10103.0 -3782.0
TNFRSF21 662.0 -1588.0
TNIK -365.0 -9615.0
TNRC6A -9124.0 -9298.0
TNRC6B -6203.0 -2867.0
TNRC6C 404.0 -4745.0
TP53 -3878.0 -8153.0
TPP1 -4887.0 -10725.0
TPR -12390.0 -14677.0
TRIB3 -12860.0 -1982.0
TRIM21 2217.0 -4632.0
TUBA1A -2200.0 -6514.0
TUBA1B -14029.0 -17230.0
TUBA1C -3384.0 -9518.0
TUBA3C -2572.0 1353.0
TUBA3D 667.0 1328.0
TUBA3E -557.0 1710.0
TUBA4A -14192.0 -8929.0
TUBA4B -12730.0 -11735.0
TUBA8 -10422.0 -5063.0
TUBAL3 -1441.0 974.0
TUBB1 474.0 -2704.0
TUBB2A -9611.0 -15207.0
TUBB2B -3861.0 -15169.0
TUBB3 -8126.0 -15236.0
TUBB4A -7628.0 279.0
TUBB4B -1709.0 -4047.0
TUBB6 -10077.0 -1707.0
TUBB8 -5845.0 1599.0
TXN -7710.0 -11678.0
TXN2 -15926.0 -6311.0
TXNIP -13682.0 -15848.0
TXNRD1 -6140.0 -5110.0
TXNRD2 -8097.0 -6159.0
UBA52 -10894.0 -4996.0
UBB -12784.0 -8060.0
UBC -11566.0 -692.0
UBE2C -14095.0 -14424.0
UBE2D1 -9905.0 -15085.0
UBE2D2 -10137.0 -16684.0
UBE2D3 -4713.0 -14451.0
UBE2E1 -7722.0 -8346.0
UBE2S -10702.0 -8077.0
UBN1 -9302.0 -11034.0
UBXN7 -12544.0 -1810.0
UFD1 -7661.0 -1409.0
USP46 1092.0 -9590.0
VCP -6950.0 -13469.0
VEGFA -4254.0 -7308.0
VENTX -15063.0 -17017.0
VHL -9255.0 -285.0
WDR24 -6510.0 -2724.0
WDR59 -491.0 -7344.0
WFS1 -7602.0 -10055.0
WIPI1 -981.0 -10848.0
WTIP -12889.0 -8368.0
XBP1 -13435.0 -354.0
XPO1 -11418.0 -13329.0
YIF1A -12190.0 -14416.0
YWHAE -7622.0 -13250.0
ZBTB17 -13122.0 -1328.0



REACTOME_CELL_CYCLE_MITOTIC

REACTOME_CELL_CYCLE_MITOTIC
metric value
setSize 540
pMANOVA 2.1e-11
p.adjustMANOVA 3.14e-09
s.dist 0.194
s.Estill -0.0966
s.Novakovic -0.168
p.Estill 0.000126
p.Novakovic 2.78e-11




Top 20 genes
Gene Estill Novakovic
E2F1 -16127.0 -16773
CDKN2B -15666.0 -17173
DBF4 -15835.5 -16964
NUP37 -15153.0 -17285
H3C12 -15164.0 -17158
NUP153 -14779.0 -17257
MAD2L1 -14859.0 -17139
CDCA5 -15196.0 -16601
KIF23 -15518.0 -16131
CDKN2D -14848.0 -16781
CDKN1C -15390.0 -16189
PSMA7 -15238.0 -16097
SMC3 -14879.0 -16404
TUBG1 -16375.0 -14891
MCM4 -14468.0 -16835
TUBA1B -14029.0 -17230
PSMD1 -15755.0 -15264
CENPO -14764.0 -16262
CCNE1 -14226.0 -16873
PPP2CA -16303.0 -14663

Click HERE to show all gene set members

All member genes
Estill Novakovic
AAAS -5233.0 -3868.0
ABL1 -712.0 -2410.0
ACTR1A -10774.0 -9995.0
AHCTF1 -2570.0 -3624.0
AJUBA -4874.0 -10340.0
AKAP9 -11760.0 -8323.0
AKT1 -6145.0 -2432.0
AKT2 -12142.0 -6370.0
AKT3 -835.0 -5588.0
ALMS1 -10177.0 -1025.0
ANAPC1 -2324.0 -5744.0
ANAPC10 -11343.0 -5816.0
ANAPC11 -15553.0 -3569.0
ANAPC15 -5573.0 -1354.0
ANAPC16 -3464.0 -3219.0
ANAPC2 -8367.0 -1213.0
ANAPC4 -11051.0 -6188.0
ANAPC5 -7613.0 -11860.0
ANAPC7 -6389.0 -4274.0
ANKLE2 -990.0 -8487.0
ARPP19 -15292.0 -9905.0
AURKA -8302.0 -8099.0
AURKB -585.0 -2715.0
B9D2 -6475.0 -5577.0
BANF1 -12198.0 -14222.0
BIRC5 -509.0 -2514.0
BLZF1 293.5 -15228.0
BORA -5571.0 -12042.0
BTRC -8741.0 -7184.0
BUB1 -406.0 -13771.0
BUB1B -2372.0 -6560.0
BUB3 -3718.0 -13578.0
CABLES1 -9757.0 -8072.0
CC2D1B -2031.0 -14994.0
CCNA1 -11907.0 -12984.0
CCNA2 -6087.0 -16501.0
CCNB1 -15812.0 -8791.0
CCNB2 -5698.0 -12010.0
CCND1 -3494.0 -11443.0
CCND2 -9651.0 -15597.0
CCND3 -13014.0 -8722.0
CCNE1 -14226.0 -16873.0
CCNE2 -10192.0 -8331.0
CCNH -7680.0 -16219.0
CCP110 -7242.0 -11338.0
CDC14A -2110.0 -10449.0
CDC16 -3120.0 -6337.0
CDC20 -14422.0 -10269.0
CDC23 -4732.0 -5268.0
CDC25A -9632.0 -11288.0
CDC25B 1208.0 -14662.0
CDC25C -5672.0 -11011.0
CDC26 -5432.0 -868.0
CDC27 -8038.0 -11129.0
CDC45 -6700.0 80.0
CDC6 -9764.0 -8910.0
CDC7 -9686.0 -12389.0
CDCA5 -15196.0 -16601.0
CDCA8 -11699.0 -15979.0
CDK1 -629.5 -12551.0
CDK11A -4310.0 -10831.0
CDK11B -3175.0 -2746.0
CDK2 -241.0 -10000.0
CDK4 -12590.0 -14349.0
CDK5RAP2 866.0 -2873.0
CDK6 -7466.0 -5435.0
CDK7 -11455.0 -8357.0
CDKN1A -7625.0 -12022.0
CDKN1B -15950.0 -12998.0
CDKN1C -15390.0 -16189.0
CDKN2A -13143.0 -1475.0
CDKN2B -15666.0 -17173.0
CDKN2C -9649.0 -15409.0
CDKN2D -14848.0 -16781.0
CDT1 -15570.0 -14862.0
CENPA -6563.0 -11218.0
CENPC -2493.0 -14292.0
CENPE -9573.0 -14208.0
CENPF -1734.0 -5756.0
CENPH -2153.0 -17067.0
CENPJ -3229.0 -6985.0
CENPK -3128.5 -16484.0
CENPL -3296.0 -14202.0
CENPM -13815.0 -6658.0
CENPN -5955.0 -11949.0
CENPO -14764.0 -16262.0
CENPP 1162.0 -12025.0
CENPQ -313.0 -6294.0
CENPS -7432.0 -6760.0
CENPT -13891.0 -13739.0
CENPU -13118.0 -12622.0
CEP131 -3422.0 -4824.0
CEP135 -16264.0 -14394.0
CEP152 -3924.0 -12738.0
CEP164 -13.0 -12119.0
CEP192 -5821.0 -2921.0
CEP250 -7889.0 -8951.0
CEP290 -346.0 -14952.0
CEP41 -7749.0 -15982.0
CEP43 -13278.0 -16552.0
CEP57 -15253.0 -12008.0
CEP63 -12858.0 -11039.0
CEP70 -8386.0 -8265.0
CEP72 -52.0 -4610.0
CEP76 -12726.0 -16607.0
CEP78 -11770.0 -9754.0
CHMP2A -6394.0 -196.0
CHMP2B -13036.0 -15756.0
CHMP3 -7699.0 8.0
CHMP4A -8786.0 -640.0
CHMP4B -15007.0 -3831.0
CHMP4C -11740.0 -15669.0
CHMP6 -13294.0 -8756.0
CHMP7 -3337.0 -3187.0
CKAP5 -7709.0 -13566.0
CKS1B -2079.0 -12778.0
CLASP1 -368.0 -10453.0
CLASP2 -14327.0 -9568.0
CLIP1 -2981.0 -8081.0
CNEP1R1 -10579.0 -7355.0
CNTRL -4976.0 -2353.0
CSNK1D -10315.0 -2827.0
CSNK1E -12689.0 -11824.0
CSNK2A1 -10932.0 -4915.0
CSNK2A2 -15748.0 -7535.0
CSNK2B -367.0 -14595.0
CTDNEP1 -7063.0 -14859.0
CUL1 -2215.0 449.0
DBF4 -15835.5 -16964.0
DCTN1 69.0 -10034.0
DCTN2 -6153.0 -1119.0
DCTN3 -12480.0 -10976.0
DHFR -5630.0 -14689.0
DNA2 -3490.0 -12624.0
DSN1 -11787.0 -7717.0
DYNC1H1 48.0 -3145.0
DYNC1I1 -7317.0 -6097.0
DYNC1I2 1732.0 -12829.0
DYNC1LI1 -11159.0 -13138.0
DYNC1LI2 -12760.0 -7326.0
DYNLL1 -11160.0 -14050.0
DYNLL2 -13828.0 -13633.0
DYRK1A -9208.0 -5694.0
E2F1 -16127.0 -16773.0
E2F2 -13924.0 -7662.0
E2F3 -4245.0 -3475.0
E2F4 -12111.0 -13562.0
E2F5 -13411.0 -7919.0
E2F6 -5691.0 -3256.0
EML4 -12051.0 -11469.0
ENSA -2087.0 -5115.0
EP300 -1567.0 -10732.0
ESCO1 -13101.0 -9854.0
ESCO2 1100.0 -7532.0
ESPL1 -8703.0 -4634.0
FBXL18 -3865.0 -1826.0
FBXL7 -618.0 -4837.0
FBXO5 -15003.0 -15440.0
FBXW11 -2863.0 -8621.0
FEN1 -3850.0 -9060.0
FKBPL -3648.0 -9083.0
FOXM1 -9091.0 -6861.0
FZR1 -7455.0 -2900.0
GINS1 -5314.0 -15131.0
GINS2 -6809.0 -14649.0
GINS3 -306.0 -3695.0
GINS4 -2971.0 -1628.0
GMNN -2029.0 -11012.0
GOLGA2 -5423.0 558.0
GORASP1 -15871.0 -8506.0
GORASP2 -2113.0 -10129.0
GSK3B -13275.0 -5625.0
GTSE1 -13342.0 -12313.0
H2AC14 -740.0 -6291.0
H2AC18 -10109.5 -16821.5
H2AC19 -10109.5 -16821.5
H2AC20 -9365.0 -421.0
H2AC4 -8682.0 -7652.0
H2AC6 -3772.0 -14402.0
H2AC7 -10309.0 -3529.5
H2AC8 -15265.0 -12472.0
H2AJ -360.0 -16792.0
H2AX -13329.0 -16764.0
H2AZ1 -10477.0 -10825.0
H2AZ2 -15177.0 -12968.0
H2BC1 930.5 1414.0
H2BC10 -12140.0 -5784.0
H2BC11 -4716.0 -15808.0
H2BC12 -3961.0 -14793.0
H2BC13 -11400.0 761.0
H2BC14 -1609.0 -8267.0
H2BC15 -2744.0 -168.0
H2BC17 -16322.0 -3166.0
H2BC21 -8996.0 -6316.0
H2BC26 -11379.0 -16861.0
H2BC3 -15205.0 -10594.0
H2BC4 -10641.0 -8955.0
H2BC5 -9533.0 315.0
H2BC6 -15206.0 266.0
H2BC7 -11776.0 -3529.5
H2BC8 -15228.0 -8541.0
H2BC9 -9951.5 -12902.5
H3-3A -13934.0 -14636.0
H3-3B -9143.0 -13971.0
H3-4 1657.0 1580.0
H3C1 -9230.0 -14629.0
H3C10 -3065.0 -374.0
H3C11 -7068.0 -13728.0
H3C12 -15164.0 -17158.0
H3C13 -4294.0 -15204.0
H3C2 -15289.0 -11553.0
H3C3 -6133.0 -14272.0
H3C4 -9971.0 -5667.0
H3C6 371.0 -17250.0
H3C7 -9951.5 -12902.5
H3C8 -15918.0 -12729.0
H4C1 -14459.0 -9617.0
H4C11 854.0 -16001.0
H4C12 -2120.0 -5312.0
H4C13 -334.0 -15402.0
H4C16 -7238.0 -8548.0
H4C2 -7763.0 -2343.0
H4C3 -5978.0 -7968.0
H4C4 -850.0 -16161.0
H4C5 -1971.0 -1886.0
H4C6 -9232.0 -16384.0
H4C8 -3484.0 -14606.0
H4C9 -10105.0 -17149.0
HAUS1 -4546.0 -13080.0
HAUS2 -13309.0 -14657.0
HAUS3 -14922.0 -6957.0
HAUS4 -13307.0 -4175.0
HAUS5 -10024.0 -12724.0
HAUS6 -5085.0 -12244.0
HAUS8 -8315.0 -10096.0
HDAC1 -9758.0 -7989.0
HMMR -8759.5 -9210.0
HSP90AA1 -13375.0 -9820.0
HSP90AB1 -11098.0 -973.0
INCENP -3511.0 -5422.0
IST1 -2314.0 -15295.0
ITGB3BP -11307.0 -12811.0
JAK2 -1045.0 -6197.0
KIF18A -11259.0 -13594.0
KIF20A -713.0 -7815.0
KIF23 -15518.0 -16131.0
KIF2A -3632.0 -14056.0
KIF2B 1804.0 1019.0
KIF2C -5345.0 -2415.0
KMT5A -9451.0 -10739.0
KNL1 -5912.0 -5397.0
KNTC1 1079.0 -10240.0
KPNB1 -14539.0 -12059.0
LBR -14393.0 -367.0
LCMT1 -7031.0 -1720.0
LEMD2 -12960.0 -11635.0
LEMD3 -4333.0 -6107.0
LIG1 -15008.0 -2042.0
LIN37 248.0 -14414.0
LIN52 -4993.0 -6014.0
LIN54 -14648.0 -2300.0
LIN9 -14550.0 -8492.0
LMNA -8291.0 -4922.0
LMNB1 -12895.0 -9972.0
LPIN1 -236.0 -5523.0
LPIN2 -14784.0 -7501.0
LPIN3 -12097.0 49.0
LYN -8344.0 -1989.0
MAD1L1 -2331.0 -1491.0
MAD2L1 -14859.0 -17139.0
MAPK1 -9762.0 -6238.0
MAPK3 -14286.0 -1298.0
MAPRE1 -7165.0 -1431.0
MASTL -11213.0 -7101.0
MAU2 -12852.0 -6757.0
MAX -6413.0 -8827.0
MCM10 -909.0 -8152.0
MCM2 -1986.0 -8659.0
MCM3 -5522.0 -10547.0
MCM4 -14468.0 -16835.0
MCM5 -1200.0 -8591.0
MCM6 -11808.0 -8449.0
MCM7 -8495.0 -8481.0
MCM8 -6147.0 -12690.0
MCPH1 -1092.0 -2898.0
MIS12 -11240.0 -17203.0
MNAT1 -2305.0 547.0
MYBL2 -4276.0 -7558.0
MYC -9179.0 -13967.0
MZT1 -6708.0 -11391.0
MZT2A -11036.0 -14936.0
MZT2B -4632.0 -14385.0
NCAPD2 -2535.0 -716.0
NCAPD3 -10865.0 -11449.0
NCAPG -9210.0 -13713.0
NCAPG2 -8767.0 -6846.0
NCAPH -11798.0 -14186.0
NCAPH2 -16362.0 -13856.0
NDC1 -11478.0 -8778.0
NDC80 -4561.0 -16763.0
NDE1 -5341.0 -4338.0
NDEL1 -13160.0 -13879.0
NEDD1 -5736.0 -2444.0
NEK2 -2328.0 -10364.0
NEK6 -6875.0 -128.0
NEK7 -8135.0 -6091.0
NEK9 -10302.0 -14259.0
NINL -11999.0 -5565.0
NIPBL -13657.0 -13686.0
NME7 293.5 -7268.0
NSL1 -7434.0 -15145.0
NUDC -14374.0 -13884.0
NUF2 -14033.0 -15760.0
NUMA1 -6928.0 -6650.0
NUP107 -7236.0 -8001.0
NUP133 -2470.0 -9143.0
NUP153 -14779.0 -17257.0
NUP155 -12129.0 -15214.0
NUP160 -11625.0 -12148.0
NUP188 -7877.0 -15187.0
NUP205 -7637.0 -436.0
NUP210 -10939.0 -191.0
NUP214 -13610.0 -5777.0
NUP35 -1428.0 -7296.0
NUP37 -15153.0 -17285.0
NUP42 -8725.0 -15797.0
NUP43 -6734.0 -13552.0
NUP50 -14109.0 -5828.0
NUP54 -12929.0 -7747.0
NUP58 -9205.0 -15350.0
NUP62 -3466.0 -2332.0
NUP85 -4129.0 -11356.0
NUP88 -7189.0 -10830.0
NUP93 -3140.0 -9015.0
NUP98 -8145.0 -10870.0
ODF2 -5350.0 -8504.0
OPTN -12236.0 -13140.0
ORC1 -5516.0 -284.0
ORC2 -128.0 -11753.0
ORC3 -10220.0 -14587.0
ORC4 -14431.0 -9786.0
ORC5 -10623.0 -6933.0
ORC6 -10847.0 -16383.0
PAFAH1B1 -7252.0 -9774.0
PCM1 -9358.0 -12737.0
PCNA -15776.0 -14982.0
PCNT -6214.0 -5445.0
PDS5A -5166.0 -9013.0
PDS5B -5500.0 -6377.0
PHLDA1 -12682.0 -10557.0
PKMYT1 -9650.0 -9140.0
PLK1 -6031.0 -5485.0
PLK4 -7554.0 -13381.0
PMF1 -8086.0 -9424.0
POLA2 -11026.0 -12985.0
POLD1 -4311.0 -6454.0
POLD2 -11066.0 470.0
POLD3 -5727.0 -13049.0
POLD4 -1289.0 -13917.0
POLE -6579.0 -2548.0
POLE2 -10276.0 -11861.0
POLE3 -7721.0 -8097.0
POLE4 -14979.0 -14320.0
POM121 -13119.0 -11642.0
POM121C -3009.0 -6792.0
PPME1 -3058.0 -14984.0
PPP1CB -3491.0 -9511.0
PPP1CC -14817.0 -9753.0
PPP1R12A -13417.0 -7769.0
PPP1R12B -154.0 -11098.0
PPP2CA -16303.0 -14663.0
PPP2CB -790.0 302.0
PPP2R1A -5112.0 -15337.0
PPP2R1B -6245.0 -9456.0
PPP2R2A -14638.0 -5917.0
PPP2R2D 1861.0 -4520.0
PPP2R5A -14844.0 -2972.0
PPP2R5B -6416.0 -16175.0
PPP2R5C -2004.0 -7658.0
PPP2R5D -13597.0 -16200.0
PPP2R5E -6877.0 -9033.0
PRIM1 -3625.0 -12956.0
PRIM2 -1166.0 -3820.0
PRKACA -15621.0 -10373.0
PRKAR2B -8749.0 -9071.0
PRKCA -1.0 -3348.0
PRKCB -1287.0 -4560.0
PSMA1 -8781.0 -2177.0
PSMA2 -7391.0 -13190.0
PSMA3 -543.0 -12585.0
PSMA4 -1489.0 -11130.0
PSMA5 -5612.0 -12086.0
PSMA6 -5453.0 -7068.0
PSMA7 -15238.0 -16097.0
PSMA8 -12998.0 1341.0
PSMB1 -7998.0 -12452.0
PSMB10 1546.0 -12645.0
PSMB11 -7675.0 461.0
PSMB2 -15087.0 -14324.0
PSMB3 -2943.0 -16574.0
PSMB4 -3092.0 -17193.0
PSMB5 -2173.0 -13304.0
PSMB6 -1270.0 -15778.0
PSMB7 1688.0 1166.0
PSMB8 251.0 -10098.0
PSMB9 -4477.0 -14712.0
PSMC1 -2414.0 -13145.0
PSMC2 -315.0 -2310.0
PSMC3 -7461.0 -17123.0
PSMC4 459.0 -4407.0
PSMC5 -9725.0 -12293.0
PSMC6 -7301.0 332.0
PSMD1 -15755.0 -15264.0
PSMD11 -6796.0 -15996.0
PSMD12 -13229.0 -1837.0
PSMD13 -9340.0 -12191.0
PSMD14 -9752.0 -14404.0
PSMD2 -5101.0 -4469.0
PSMD3 -6030.0 -12489.0
PSMD4 -6049.0 -14518.0
PSMD5 2564.0 -8724.0
PSMD6 -5979.0 -12939.0
PSMD7 -12233.0 -5710.0
PSMD8 -9781.0 -13888.0
PSMD9 -11408.0 -10645.0
PSME1 -9760.0 -16962.0
PSME2 67.0 -15711.0
PSME3 -4965.0 -13719.0
PSME4 -13130.0 -13058.0
PSMF1 -12443.0 -3758.0
PTK6 -14982.0 -2393.0
PTTG1 -3508.0 -13806.0
RAB1A -11800.0 -11205.0
RAB1B -11811.0 -13124.0
RAB2A -15533.0 -5166.0
RAB8A -2437.0 -12675.0
RAD21 -13034.0 -4206.0
RAE1 -10699.0 -7730.0
RAN -10662.0 -16269.0
RANBP2 -8430.0 -15721.0
RANGAP1 -7181.0 -12265.0
RB1 -9395.0 -7632.0
RBBP4 -9690.0 -15408.0
RBL1 823.0 -5072.0
RBL2 -7303.0 -11548.0
RBX1 -6001.0 -10254.0
RCC1 -308.0 -2368.0
RCC2 -5320.0 -5307.0
RFC1 -11317.0 -9485.0
RFC2 -11390.0 -13410.0
RFC3 1547.0 -8638.0
RFC4 -12661.0 -13699.0
RFC5 -3459.0 -7830.0
RPA1 1482.0 -2054.0
RPA2 -6976.0 -8172.0
RPA3 -13260.0 -8291.0
RPS27 1722.0 -11381.0
RPS27A -11481.0 -2147.0
RRM2 -10442.0 -8505.0
SDCCAG8 -4661.0 -3633.0
SEC13 -8604.0 -10471.0
SEH1L -8901.0 -14935.0
SEM1 -1388.0 -14801.0
SET -8737.0 -6532.0
SFI1 -12444.0 -11569.0
SGO1 -4675.0 -4366.0
SGO2 -1842.0 -8446.0
SIRT2 -6884.0 -9850.0
SKA1 -6465.0 -16444.0
SKA2 -5163.0 -5832.0
SKP1 -9613.0 -15257.0
SKP2 -3788.0 -6780.0
SMC2 -6739.0 -8249.0
SMC3 -14879.0 -16404.0
SMC4 -14508.0 -9211.0
SPAST -15874.0 -9503.0
SPC24 -11068.0 -15981.0
SPC25 -3265.0 -2763.0
SPDL1 -5198.0 -9012.0
SRC -8945.0 -2260.0
SSNA1 -5964.0 -8575.0
STAG1 -4192.0 -10829.0
SUMO1 -32.0 -9758.0
TAOK1 -12592.0 -8943.0
TFDP1 -507.0 -45.0
TFDP2 -14013.0 -2679.0
TK1 -4756.0 -10019.0
TMPO -15535.0 -8262.0
TNPO1 -12905.0 -8329.0
TOP2A -4473.0 -4314.0
TP53 -3878.0 -8153.0
TPR -12390.0 -14677.0
TPX2 -11984.0 308.0
TUBA1A -2200.0 -6514.0
TUBA1B -14029.0 -17230.0
TUBA1C -3384.0 -9518.0
TUBA3C -2572.0 1353.0
TUBA3D 667.0 1328.0
TUBA3E -557.0 1710.0
TUBA4A -14192.0 -8929.0
TUBA4B -12730.0 -11735.0
TUBA8 -10422.0 -5063.0
TUBAL3 -1441.0 974.0
TUBB -4832.0 -14732.0
TUBB1 474.0 -2704.0
TUBB2A -9611.0 -15207.0
TUBB2B -3861.0 -15169.0
TUBB3 -8126.0 -15236.0
TUBB4A -7628.0 279.0
TUBB4B -1709.0 -4047.0
TUBB6 -10077.0 -1707.0
TUBB8 -5845.0 1599.0
TUBG1 -16375.0 -14891.0
TUBG2 -2182.0 -9317.0
TUBGCP2 -2326.0 -864.0
TUBGCP3 -11364.0 -8086.0
TUBGCP4 -14320.0 -6397.0
TUBGCP5 -5996.0 -13306.0
TUBGCP6 -5866.0 -11053.0
TYMS -9594.0 -16610.0
UBA52 -10894.0 -4996.0
UBB -12784.0 -8060.0
UBC -11566.0 -692.0
UBE2C -14095.0 -14424.0
UBE2D1 -9905.0 -15085.0
UBE2E1 -7722.0 -8346.0
UBE2I -10552.0 -5939.0
UBE2S -10702.0 -8077.0
USO1 -8214.0 -10133.0
VPS4A -6364.0 -13269.0
VRK1 -14545.0 -13800.0
VRK2 -11405.0 -3325.0
WAPL -15001.0 -14312.0
WEE1 -13550.0 -14529.0
XPO1 -11418.0 -13329.0
YWHAE -7622.0 -13250.0
YWHAG -5540.0 -4226.0
ZW10 -1493.0 -10411.0
ZWILCH -15096.0 -2173.0
ZWINT -11659.0 -15238.0



REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION
metric value
setSize 1346
pMANOVA 3.26e-09
p.adjustMANOVA 4.46e-07
s.dist 0.113
s.Estill -0.0669
s.Novakovic -0.0916
p.Estill 4.15e-05
p.Novakovic 1.99e-08




Top 20 genes
Gene Estill Novakovic
GMPPB -16302 -17195
NEURL2 -16332 -16632
FOXL2 -15434 -17277
ARF5 -16236 -16256
GALNT4 -15668 -16748
NUP37 -15153 -17285
KCTD6 -15793 -16502
NSMCE4A -16050 -16018
NUP153 -14779 -17257
KCTD7 -15612 -16307
SEC24A -16357 -15536
EIF5A2 -14953 -16979
FUOM -14691 -17167
SPRN -16431 -15262
ACTB -14421 -17178
CBX8 -15191 -16149
PSMA7 -15238 -16097
UBA3 -15541 -15740
SMC3 -14879 -16404
LYPD2 -15924 -15297

Click HERE to show all gene set members

All member genes
Estill Novakovic
A4GNT -804.0 -12735.0
AAAS -5233.0 -3868.0
ABRAXAS1 -9135.0 -15398.0
ABRAXAS2 -15658.0 -8527.0
ACTB -14421.0 -17178.0
ACTL6A -9017.0 -11605.0
ACTR10 -7672.0 -17095.0
ACTR1A -10774.0 -9995.0
ACTR5 -12449.0 -5847.0
ACTR8 -7010.0 -4217.0
ADAM10 -3723.0 -10973.0
ADAMTS1 -2472.0 -6815.0
ADAMTS10 -2993.0 -6857.0
ADAMTS12 655.0 -4765.0
ADAMTS13 -15051.0 -10043.0
ADAMTS14 -3973.0 -812.0
ADAMTS15 -8017.0 -15651.0
ADAMTS16 -3072.0 -3919.0
ADAMTS17 -7136.0 -2454.0
ADAMTS18 -9664.0 -11656.0
ADAMTS19 -14464.0 -14653.0
ADAMTS2 -5124.0 -1859.0
ADAMTS20 -1281.0 -4568.0
ADAMTS3 -14078.0 -9368.0
ADAMTS4 -8534.0 -3097.0
ADAMTS5 -1553.0 -10604.0
ADAMTS6 592.0 -427.0
ADAMTS7 -2627.0 -14280.0
ADAMTS8 -12033.0 -10051.0
ADAMTS9 -3480.0 -5773.0
ADAMTSL1 609.0 -11610.0
ADAMTSL2 -12445.0 -10341.0
ADAMTSL3 -9190.0 -6130.0
ADAMTSL4 -8797.0 -6076.0
ADAMTSL5 -9918.0 -11557.0
ADRB2 -13214.0 -16090.0
ADRM1 -14317.0 -11124.0
AGBL1 307.0 -4918.0
AGBL2 1705.0 -14123.0
AGBL3 -12229.0 -14906.0
AGBL4 -9378.0 -3227.0
AGBL5 -11202.0 -13816.0
AGTPBP1 -14742.0 -6891.0
AHSG -1504.0 -9006.0
ALB -7500.0 -15417.0
ALG1 -5289.0 -4356.0
ALG10 -12672.0 -10085.0
ALG10B -2887.0 -9781.0
ALG11 -5472.0 -12746.0
ALG12 -13363.0 -15186.0
ALG14 -7812.0 -8972.0
ALG2 -5808.5 -13357.0
ALG3 -15341.0 -10653.0
ALG5 -9357.0 -7773.0
ALG6 -15477.0 -15477.0
ALG8 -10426.0 -10997.0
ALG9 -5842.0 -10195.0
ALPG -858.0 -12324.0
ALPI -11891.0 -6455.0
ALPL -6426.0 -4766.0
AMDHD2 -12086.0 936.0
AMFR 1321.0 -13286.0
AMTN -10356.0 -139.0
ANK1 -7081.0 -5233.0
ANK2 -186.0 -7645.0
ANK3 0.0 -4643.0
ANKRD28 -6283.0 -1742.0
ANKRD9 -7892.0 -10569.0
ANO8 -11638.0 -5411.0
APC -6050.0 -14181.0
APLP2 -2188.0 -2792.0
APOA1 -7264.0 -5044.0
APOA2 932.0 -137.0
APOA5 -12901.0 -11111.0
APOB 340.0 -10566.0
APOE -5441.0 -1114.0
APOL1 1283.0 -4238.0
APP -5839.0 -4563.0
ARCN1 762.0 -12918.0
AREG -6576.0 -1081.0
ARF1 -13286.0 -5475.0
ARF3 -3006.0 -12200.0
ARF4 -12795.0 -11186.0
ARF5 -16236.0 -16256.0
ARFGAP1 -15805.0 -11740.0
ARFGAP2 -9567.0 -8054.0
ARFGAP3 -5465.0 -1384.0
ARRB1 -10616.0 -500.0
ARRB2 -15269.0 -9310.0
ARSA -9743.0 -16181.0
ARSB -3284.0 -2502.0
ARSG -11582.0 -5038.0
ARSI -3994.0 -4493.0
ARSJ -10700.0 -15051.0
ARSK -7565.0 -6747.0
ART3 -6710.0 -306.0
ART4 599.0 -6001.0
ASB1 -1235.0 -4580.0
ASB10 -14072.0 -5200.0
ASB13 -2473.0 -8600.0
ASB14 694.0 -11373.0
ASB15 479.0 -6185.0
ASB16 -6912.0 -5686.0
ASB18 -2226.0 -1579.0
ASB2 -9442.0 -2012.0
ASB3 -5310.0 -8183.0
ASB4 2196.0 -1841.0
ASB5 -16095.0 -9100.0
ASB6 -4727.0 -5688.0
ASB7 -2419.0 -7083.0
ASB8 -9288.0 -9220.0
ASGR1 -9183.0 -13761.0
ASGR2 -148.0 364.0
ASXL1 -7660.0 -9126.0
ASXL2 -8282.0 -4723.0
ATXN3 -13152.0 -11284.0
ATXN7 -12466.0 -13195.0
AURKA -8302.0 -8099.0
AURKB -585.0 -2715.0
AXIN1 -2253.0 -3623.0
AXIN2 -5471.0 -12043.0
B3GALNT2 -15188.0 -2994.0
B3GLCT -4308.0 -8920.0
B3GNT2 -14755.0 -15138.0
B3GNT3 -3849.0 -2023.0
B3GNT4 -11313.0 -8448.0
B3GNT5 -5065.0 -6212.0
B3GNT6 -2424.0 -6476.0
B3GNT7 -11099.0 -7316.0
B3GNT8 897.0 -11160.0
B3GNT9 -6028.0 -15247.0
B3GNTL1 218.0 -1844.0
B4GALNT2 -13091.0 -11834.0
B4GALT1 -11009.0 -8215.0
B4GALT2 -15233.0 -4101.0
B4GALT3 -15331.0 -11506.0
B4GALT4 -14543.0 -11897.0
B4GALT5 -15961.0 -620.0
B4GALT6 -11922.0 -3745.0
BABAM1 -7407.0 -16872.0
BABAM2 -2016.0 -4347.0
BAP1 -13602.0 -11932.0
BARD1 -9780.0 -7224.0
BCL10 -5105.0 -10767.0
BECN1 -3483.0 -10723.0
BET1 -258.0 -11934.0
BET1L -4234.0 -16196.0
BGLAP -7204.0 -11376.0
BIRC2 -13818.0 -16329.0
BIRC3 -2266.0 -6056.0
BIRC5 -509.0 -2514.0
BLM -8164.0 -12810.0
BMI1 -16012.0 -13112.0
BMP4 -7654.0 -13436.0
BPIFB2 534.0 -9118.0
BRCA1 2021.0 628.0
BST1 -798.0 -4196.0
BTBD1 -13443.0 -11526.0
BTBD6 -13710.0 -12731.0
BTRC -8741.0 -7184.0
C1GALT1 -1085.0 -15163.0
C3 -3487.0 -4048.0
C4A -9092.5 1061.0
CALM1 -11935.0 -10428.0
CALR -6453.0 -8798.0
CALU -16187.0 -9921.0
CAMKMT -9718.0 -8857.0
CAND1 -6817.0 -9259.0
CANX -15020.0 -1402.0
CAPZA1 -3504.0 -10215.0
CAPZA2 -13595.0 -14422.0
CAPZA3 -292.0 571.0
CAPZB 383.0 -902.0
CBX2 -14491.0 -6483.0
CBX4 -7580.0 -13492.0
CBX5 -8663.0 -2470.0
CBX8 -15191.0 -16149.0
CCDC8 -6828.0 -2013.0
CCN1 -6345.0 -8266.0
CCNA1 -11907.0 -12984.0
CCNA2 -6087.0 -16501.0
CCNF -3247.0 -5612.0
CCP110 -7242.0 -11338.0
CD109 -6554.0 -15758.0
CD52 -6850.0 834.0
CD55 -12576.0 -5644.0
CD59 -2659.0 -10327.0
CDC20 -14422.0 -10269.0
CDC25A -9632.0 -11288.0
CDC34 -11242.0 -5868.0
CDC73 -13398.0 -6655.0
CDCA8 -11699.0 -15979.0
CDH2 -6613.0 -12303.0
CDK1 -629.5 -12551.0
CDKN1A -7625.0 -12022.0
CDKN2A -13143.0 -1475.0
CEACAM5 -7513.0 826.0
CEACAM7 -8294.0 -432.0
CFTR -4006.0 -4762.0
CGA -16413.0 -6356.0
CHD3 -3938.0 -1979.0
CHGB -12830.0 -16365.0
CHML -414.0 1311.0
CHST10 -3329.0 -13109.0
CHST4 -2350.0 225.0
CHST8 -9068.0 -3332.0
CISH -12548.0 -15728.0
CKAP4 -12255.0 -12088.0
CLSPN -6560.0 -13561.0
CMAS -5172.0 -11345.0
CNIH1 -15665.0 -8419.0
CNIH2 -14341.0 -14075.0
CNIH3 -1914.0 -4621.0
CNTN4 -2080.0 -3115.0
CNTN5 -8125.0 -5494.0
COG1 -2865.0 -7042.0
COG2 -7460.0 -15044.0
COG3 -5108.0 -2925.0
COG4 -9565.0 -10150.0
COG5 -5853.0 -9635.0
COG6 -9301.0 -13898.0
COG7 -912.0 -5407.0
COG8 -14068.0 -12411.0
COL7A1 -15784.0 -9050.0
COMMD1 -5113.0 320.0
COMMD10 -14048.0 -3215.0
COMMD2 -7309.0 -15624.0
COMMD3 -12696.0 -5634.0
COMMD4 -11961.0 -10079.0
COMMD5 -15239.0 -7422.0
COMMD6 -451.0 -14630.0
COMMD7 -12043.0 -9329.0
COMMD8 -10056.0 -7396.0
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PARP1 -5678.0 -1342.0
PCGF2 -13952.0 -13875.0
PCNA -15776.0 -14982.0
PCSK9 -7489.0 -8841.0
PDIA3 -12219.0 -12688.0
PDIA6 -11142.0 -4172.0
PENK -14554.0 -12532.0
PEX10 -11682.0 -7143.0
PEX12 -13434.0 -16533.0
PEX13 -4612.0 -4648.0
PEX14 -2159.0 -4358.0
PEX2 -13180.0 -7385.0
PEX5 -11356.0 -8062.0
PGAP1 -10373.0 -16319.0
PGM3 -8872.0 -12917.0
PGR -11785.0 9.0
PHC1 -12792.0 -12915.0
PHC2 -2255.0 -5791.0
PHC3 -6951.0 -7813.0
PIAS1 -13990.0 -3876.0
PIAS2 -8953.0 -15890.0
PIAS3 -4305.0 -12083.0
PIAS4 -11745.0 -8067.0
PIGB -2780.0 -15308.0
PIGC -3386.0 -16566.0
PIGF -8598.0 -8441.0
PIGG -590.0 -799.0
PIGH -6261.0 -14644.0
PIGK -8893.0 -10012.0
PIGL -952.0 -5302.0
PIGM -3018.0 -14700.0
PIGN -13126.0 -7544.0
PIGO 644.0 -15132.0
PIGP -10523.0 -14447.0
PIGQ -11290.0 -9125.0
PIGS -799.0 -11858.0
PIGT -9654.0 -14609.0
PIGU -5975.0 -2232.0
PIGV -14694.0 -16478.0
PIGW -12118.0 -9215.0
PIGX -9127.0 -16519.0
PIGY -13178.0 -8887.0
PIGZ -9882.0 294.0
PLAUR -10035.0 -2395.0
PLET1 1685.0 -8313.0
PML 884.0 -927.0
PMM1 -15181.0 -5291.0
PMM2 -3564.0 -8187.0
PNPLA2 -15158.0 -1198.0
POFUT2 -4022.0 -995.0
POLB -2826.0 -10425.0
POM121 -13119.0 -11642.0
POM121C -3009.0 -6792.0
POMGNT1 -11932.0 -2428.0
POMGNT2 -693.0 -8675.0
POMK -15042.0 -11741.0
POMT1 -9800.0 -5520.0
POMT2 -9350.0 -7772.0
PPARA 321.0 -4843.0
PPARG -10949.0 -8800.0
PPARGC1A -2243.0 44.0
PPP6C -7477.0 -14931.0
PPP6R1 -11260.0 -12865.0
PPP6R3 -6901.0 -6535.0
PREB 101.0 -11463.0
PRKCSH -3401.0 -8168.0
PRKDC -3499.0 -10253.0
PRKN -309.0 -1304.0
PRMT3 -11622.0 -16893.0
PRND -5823.0 -8927.0
PROC -3877.0 63.0
PROS1 -13923.0 -4088.0
PROZ -1592.0 -2569.0
PRSS21 -14279.0 347.0
PRSS23 -4119.0 -8719.0
PRSS41 -3078.0 931.0
PSCA -12642.0 -7.0
PSMA1 -8781.0 -2177.0
PSMA2 -7391.0 -13190.0
PSMA3 -543.0 -12585.0
PSMA4 -1489.0 -11130.0
PSMA5 -5612.0 -12086.0
PSMA6 -5453.0 -7068.0
PSMA7 -15238.0 -16097.0
PSMA8 -12998.0 1341.0
PSMB1 -7998.0 -12452.0
PSMB10 1546.0 -12645.0
PSMB11 -7675.0 461.0
PSMB2 -15087.0 -14324.0
PSMB3 -2943.0 -16574.0
PSMB4 -3092.0 -17193.0
PSMB5 -2173.0 -13304.0
PSMB6 -1270.0 -15778.0
PSMB7 1688.0 1166.0
PSMB8 251.0 -10098.0
PSMB9 -4477.0 -14712.0
PSMC1 -2414.0 -13145.0
PSMC2 -315.0 -2310.0
PSMC3 -7461.0 -17123.0
PSMC4 459.0 -4407.0
PSMC5 -9725.0 -12293.0
PSMC6 -7301.0 332.0
PSMD1 -15755.0 -15264.0
PSMD11 -6796.0 -15996.0
PSMD12 -13229.0 -1837.0
PSMD13 -9340.0 -12191.0
PSMD14 -9752.0 -14404.0
PSMD2 -5101.0 -4469.0
PSMD3 -6030.0 -12489.0
PSMD4 -6049.0 -14518.0
PSMD5 2564.0 -8724.0
PSMD6 -5979.0 -12939.0
PSMD7 -12233.0 -5710.0
PSMD8 -9781.0 -13888.0
PSMD9 -11408.0 -10645.0
PSME1 -9760.0 -16962.0
PSME2 67.0 -15711.0
PSME3 -4965.0 -13719.0
PSME4 -13130.0 -13058.0
PSMF1 -12443.0 -3758.0
PTEN -14678.0 -7735.0
PTP4A2 -10119.0 -1465.0
PTRH2 -363.0 -10145.0
PUM2 -526.0 -5447.0
QSOX1 -8199.0 -8581.0
RAB10 -9623.0 -10683.0
RAB11A -14652.0 -9163.0
RAB11B -9487.0 -10893.0
RAB12 -1389.0 -12451.0
RAB13 -3630.0 -5643.0
RAB14 -5021.0 -4240.0
RAB15 -5408.0 -5584.0
RAB17 -15547.0 -305.0
RAB18 -14645.0 -13869.0
RAB19 -6952.0 -4195.0
RAB1A -11800.0 -11205.0
RAB1B -11811.0 -13124.0
RAB20 -6358.0 -7233.0
RAB21 -3132.0 -13008.0
RAB22A -15783.0 -11499.0
RAB23 -14977.0 -10728.0
RAB24 -15168.0 -14307.0
RAB25 -15352.0 -1730.0
RAB26 -14984.0 376.0
RAB27A -4428.0 -1366.0
RAB27B -4382.0 -16003.0
RAB29 483.0 -4891.0
RAB2A -15533.0 -5166.0
RAB2B -4475.0 -1511.0
RAB30 -3704.0 -2110.0
RAB31 -6801.0 -2800.0
RAB32 -7657.0 -3003.0
RAB33B -15966.0 -15036.0
RAB34 -5703.0 -7430.0
RAB35 -860.0 -11513.0
RAB36 -5815.0 -9519.0
RAB37 -12227.0 -8444.0
RAB38 -3256.0 -14765.0
RAB3A -15038.0 -3037.0
RAB3B -7828.0 -7949.0
RAB3C -3770.0 -7151.0
RAB3D -872.0 -2930.0
RAB40B -5070.0 -8717.0
RAB40C -5683.0 -4763.0
RAB42 -12834.0 -3581.0
RAB43 -16285.0 -5366.0
RAB4A -15423.0 -11927.0
RAB4B -9252.0 -6870.0
RAB5A -4972.0 -14940.0
RAB5B -14096.0 -1256.0
RAB5C -8082.0 -12184.0
RAB6A -13573.0 -15694.0
RAB6B -8981.0 -3679.0
RAB7A -4289.0 -2505.0
RAB8A -2437.0 -12675.0
RAB8B -11755.0 -11609.0
RABGGTA -9683.0 -12255.0
RABGGTB -5319.0 -3999.0
RAD18 -9227.0 -368.0
RAD21 -13034.0 -4206.0
RAD23A -10135.0 -14209.0
RAD23B -13764.0 -7138.0
RAD52 -1922.0 -5851.0
RAE1 -10699.0 -7730.0
RAET1G -3594.0 -100.0
RAET1L -3330.0 -1611.0
RANBP2 -8430.0 -15721.0
RANGAP1 -7181.0 -12265.0
RARA -10604.0 -9543.0
RBBP5 -12137.0 -1239.0
RBX1 -6001.0 -10254.0
RCE1 -10518.0 -16182.0
RCN1 -6250.0 -6134.0
RECK 709.0 -4780.0
RELA -15610.0 -9300.0
RFT1 -4183.0 -4095.0
RHOA -15122.0 -4532.0
RHOT1 -9479.0 -12997.0
RIGI 658.0 -13449.0
RING1 -5983.0 -3121.0
RIPK1 2218.0 -8321.0
RIPK2 -16417.0 -13521.0
RNF103 -9969.0 -16399.0
RNF123 -13938.0 -11872.0
RNF135 2465.0 -12124.0
RNF139 -15721.0 -4667.0
RNF144A -8506.0 -3077.0
RNF146 -6320.0 -13864.0
RNF152 561.0 -9382.0
RNF168 -3627.0 -5998.0
RNF181 -3310.0 -12563.0
RNF185 -12859.0 -12328.0
RNF2 -3565.0 -967.0
RNF20 -5097.0 -9675.0
RNF40 -1528.0 -3384.0
RNF5 -175.0 -549.0
RNF7 -15861.0 -4714.0
RORA -2327.0 -6546.0
RPA1 1482.0 -2054.0
RPN1 -12573.0 -5768.0
RPN2 -7951.0 -10026.0
RPS2 -8403.0 -13161.0
RPS27A -11481.0 -2147.0
RRAGA -1430.0 -17105.0
RTF1 -1697.0 -12745.0
RTN4RL1 -8815.0 -6260.0
RTN4RL2 -6821.0 -7393.0
RUVBL1 -10977.0 -7680.0
RWDD3 -15236.0 -4803.0
RXRA -6530.0 -1218.0
SAE1 -15962.0 -8633.0
SAFB -9753.0 -8501.0
SAR1B -10092.0 -10733.0
SATB1 -432.0 -9621.0
SATB2 -10983.0 -13681.0
SBSPON -10660.0 -4440.0
SCFD1 -3621.0 -14604.0
SCG2 1896.0 -2122.0
SCG3 -3719.0 -2170.0
SCMH1 -4232.0 -9009.0
SDC2 -5455.0 -13416.0
SEC13 -8604.0 -10471.0
SEC16A -3165.0 -5075.0
SEC16B 2077.0 -2130.0
SEC22A -3700.0 -11947.0
SEC22B -68.0 -4345.0
SEC22C -14647.0 -3736.0
SEC23A -5849.0 -15631.0
SEC23IP -8022.0 -7879.0
SEC24A -16357.0 -15536.0
SEC24B -6910.0 -14357.0
SEC24C -12285.0 -2295.0
SEC24D -12021.0 -10149.0
SEC31A -15136.0 -11060.0
SEH1L -8901.0 -14935.0
SEL1L -6066.0 -578.0
SELENOS -9860.0 -5994.0
SEM1 -1388.0 -14801.0
SEMA5A -1082.0 -5770.0
SEMA5B -2208.0 -3446.0
SENP1 -8620.0 -12788.0
SENP2 -7335.0 -7097.0
SENP5 -9095.0 -4863.0
SENP8 -12001.0 -10406.0
SERPINA1 -4176.0 415.0
SERPINA10 -2955.0 -9428.0
SERPINC1 557.0 -7850.0
SERPIND1 738.0 -2599.0
SHISA5 -9094.0 -8865.0
SHPRH -11130.0 -12905.0
SIAH2 -7546.0 -1410.0
SIN3A -7719.0 -12217.0
SKIC8 -9348.0 -3901.0
SKP1 -9613.0 -15257.0
SKP2 -3788.0 -6780.0
SLC17A5 -9947.0 -953.0
SLC35A1 -12644.0 -3049.0
SLC35C1 -14903.0 -13370.0
SMAD1 -9856.0 -7722.0
SMAD2 -15862.0 -14174.0
SMAD3 -1318.0 -4572.0
SMAD4 -11918.0 -15024.0
SMAD7 -8955.0 -12493.0
SMC3 -14879.0 -16404.0
SMC5 -8838.0 -10828.0
SMC6 -13465.0 -14137.0
SMURF2 -15717.0 -11044.0
SNX3 -2558.0 -4424.0
SOCS2 -13731.0 -17078.0
SOCS3 -8896.0 -17163.0
SOCS5 -10767.0 -6126.0
SOCS6 -4942.0 -15727.0
SP100 -4409.0 806.0
SP3 -9830.0 -15259.0
SPACA4 -11049.0 -7810.0
SPARCL1 -20.0 -5204.0
SPON1 -1767.0 -11978.0
SPON2 -14535.0 -3154.0
SPP1 2551.0 561.0
SPP2 2126.0 -13939.0
SPRN -16431.0 -15262.0
SPSB1 -5094.0 -2850.0
SPSB2 -7743.0 -17169.0
SPSB3 -9934.0 -5937.0
SPSB4 -12107.0 -5718.0
SPTA1 1707.0 -6701.0
SPTAN1 -14229.0 -9717.0
SPTB -2337.0 -1816.0
SPTBN1 280.0 -6570.0
SPTBN2 -4386.0 -1911.0
SPTBN4 -11136.0 -12107.0
SPTBN5 -9142.0 -3494.0
SQSTM1 -10407.0 -9268.0
SRD5A3 -10881.0 -14371.0
SSPOP -11168.0 -2449.0
ST3GAL1 -472.0 -5959.0
ST3GAL2 -6148.0 -8627.0
ST3GAL3 365.0 -3381.0
ST3GAL4 -2005.0 -7956.0
ST3GAL5 -2595.0 -10624.0
ST3GAL6 -6369.0 -2389.0
ST6GAL1 1439.0 -3948.0
ST6GAL2 -3819.0 -8990.0
ST6GALNAC1 642.0 -13548.0
ST6GALNAC2 -11179.0 -9196.0
ST6GALNAC3 -5712.0 -11276.0
ST6GALNAC4 -23.0 -4222.0
ST6GALNAC5 -11944.0 -14428.0
ST6GALNAC6 -1594.0 -4472.0
ST8SIA1 -7693.0 -4229.0
ST8SIA2 -7004.0 -2861.0
ST8SIA3 -11413.0 -14182.0
ST8SIA4 -13044.0 -9226.0
ST8SIA5 -4553.0 18.0
ST8SIA6 -12073.0 -3725.0
STAG1 -4192.0 -10829.0
STAM -12935.0 -9941.0
STAM2 -15609.0 -15505.0
STAMBP -7555.0 -9193.0
STAMBPL1 -12467.0 -12529.0
STC2 -7673.0 -2606.0
STT3A -6093.0 -15573.0
STX17 -13970.0 -10135.0
STX5 -7776.0 -206.0
SUDS3 -12701.0 -3410.0
SUMF1 -5277.0 -10509.0
SUMF2 -5118.0 -11452.0
SUMO1 -32.0 -9758.0
SUMO2 -14037.0 -12856.0
SUMO3 -14329.0 -12467.0
SUZ12 -12029.0 -10907.0
SVBP -4761.0 -14339.0
SYVN1 -12854.0 -11547.0
TAB1 -10168.0 -3850.0
TADA2B -13148.0 -6645.0
TADA3 -10361.0 -15577.0
TAF10 -15058.0 -15107.0
TBC1D20 -9496.0 -5409.0
TDG -9045.0 -13531.0
TECTA -245.0 -596.0
TECTB 942.0 1018.0
TEX101 39.0 -1453.0
TF -13395.0 -13079.0
TFAP2A -9759.0 -9795.0
TFAP2B -13031.0 -11077.0
TFAP2C -13795.0 -9796.0
TFG -13224.0 -7791.0
TFPT -9263.0 -2957.0
TGFA -10486.0 -12128.0
TGFB1 -11372.0 -5923.0
TGFBR1 -819.0 -4078.0
TGFBR2 -1846.0 -11631.0
TGOLN2 -4247.0 -4128.0
THBS1 -1397.0 -6668.0
THBS2 -4944.0 -6403.0
THRA -4678.0 -9241.0
THRB -12862.0 -10868.0
THSD1 -16388.0 1039.0
THSD4 1636.0 -4943.0
THSD7A -4207.0 -4966.0
THSD7B -2764.0 -1007.0
THY1 -11064.0 -11340.0
TMED10 -295.0 -178.0
TMED2 -16180.0 -11421.0
TMED3 -10566.0 -8184.0
TMED7 -8546.0 -16546.0
TMED9 -9522.0 -12975.0
TMEM115 -4714.0 -16844.0
TMEM129 -11940.0 -12921.0
TMEM132A -10975.0 -5820.0
TNC -1720.0 -1592.0
TNFAIP3 -9916.0 -13186.0
TNIP1 -5812.0 -3506.0
TNIP2 -10708.0 -14759.0
TNIP3 -1954.0 -8165.0
TNKS -8385.0 -9827.0
TNKS2 -15818.0 -11527.0
TOMM20 -9548.0 -8494.0
TOMM70 -4078.0 -16306.0
TOP1 -10172.0 -10718.0
TOP2A -4473.0 -4314.0
TOP2B -16053.0 -11312.0
TOPORS -2952.0 -11817.0
TP53 -3878.0 -8153.0
TP53BP1 -461.0 -10402.0
TPGS1 -12335.0 -14524.0
TPGS2 -3809.0 -12876.0
TPR -12390.0 -14677.0
TPST1 -10459.0 -5630.0
TPST2 -1572.0 -1302.0
TRAF2 -6879.0 -2904.0
TRAF3 -5923.0 -4808.0
TRAF6 -13746.0 -16063.0
TRAPPC1 -11857.0 -6378.0
TRAPPC10 -856.0 -6693.0
TRAPPC2L -16061.0 -14608.0
TRAPPC3 -11178.0 -15757.0
TRAPPC4 -2832.0 -12710.0
TRAPPC5 -9503.0 -8986.0
TRAPPC6A -12953.0 -4606.0
TRAPPC6B -9495.0 -13736.0
TRAPPC9 -136.0 -2511.0
TRIM13 -9801.0 -4653.0
TRIM25 -5651.0 -16716.0
TRIM27 -1049.0 -12367.0
TRIM28 -8177.0 -13550.0
TRIM4 -8264.0 -3720.0
TRRAP 581.0 -6016.0
TTL -9790.0 -10178.0
TTLL1 -6709.0 -7338.0
TTLL10 -8497.0 -1228.0
TTLL11 -682.0 -3980.0
TTLL12 -10790.0 -6390.0
TTLL13 -2157.0 949.0
TTLL2 -751.0 -2414.0
TTLL3 -6254.0 -6675.0
TTLL4 -11373.0 -1814.0
TTLL5 1072.0 -6874.0
TTLL6 -11389.0 -6440.0
TTLL7 -11752.0 -5306.0
TTLL8 -918.0 528.0
TTLL9 -6469.0 -16380.0
TUBA1A -2200.0 -6514.0
TUBA1B -14029.0 -17230.0
TUBA1C -3384.0 -9518.0
TUBA3C -2572.0 1353.0
TUBA3D 667.0 1328.0
TUBA3E -557.0 1710.0
TUBA4A -14192.0 -8929.0
TUBA4B -12730.0 -11735.0
TUBA8 -10422.0 -5063.0
TUBAL3 -1441.0 974.0
TUBB1 474.0 -2704.0
TUBB2A -9611.0 -15207.0
TUBB2B -3861.0 -15169.0
TUBB3 -8126.0 -15236.0
TUBB4A -7628.0 279.0
TUBB4B -1709.0 -4047.0
TUBB6 -10077.0 -1707.0
TUBB8 -5845.0 1599.0
TULP4 1813.0 -4699.0
TUSC3 -6658.0 -12520.0
UAP1 -14454.0 -11844.0
UBA2 -13632.0 -3714.0
UBA3 -15541.0 -15740.0
UBA52 -10894.0 -4996.0
UBA6 -9789.0 -11243.0
UBB -12784.0 -8060.0
UBC -11566.0 -692.0
UBD 971.0 1249.0
UBE2B -11942.0 -10699.0
UBE2C -14095.0 -14424.0
UBE2D1 -9905.0 -15085.0
UBE2D2 -10137.0 -16684.0
UBE2D3 -4713.0 -14451.0
UBE2E1 -7722.0 -8346.0
UBE2E3 -14250.0 -13936.0
UBE2F -12892.0 -7280.0
UBE2G1 -7779.0 -13836.0
UBE2G2 -13994.0 -15767.0
UBE2H -2377.0 -10682.0
UBE2I -10552.0 -5939.0
UBE2J2 -1793.0 -4300.0
UBE2K -12890.0 -7960.0
UBE2L3 -5074.0 -2077.0
UBE2M -12213.0 -9760.0
UBE2N -9458.0 -16754.0
UBE2Q2 -8203.0 -7541.0
UBE2R2 299.0 -9908.0
UBE2S -10702.0 -8077.0
UBE2T -1365.0 644.0
UBE2V2 -16133.0 -1676.0
UBE2W -1582.0 -11839.0
UBE2Z -11861.0 -7806.0
UBXN1 -9590.0 -6173.0
UBXN7 -12544.0 -1810.0
UCHL1 -7641.0 -16150.0
UCHL3 -1957.0 -12712.0
UCHL5 -15680.5 -8840.0
UFD1 -7661.0 -1409.0
UGGT1 -12715.0 -11682.0
UGGT2 -12668.0 -11162.0
UHRF2 -11603.0 -11240.0
UIMC1 -9235.0 -8424.0
ULBP2 -11269.0 -16188.0
UMOD -1627.0 -12141.0
USO1 -8214.0 -10133.0
USP10 -6314.0 -9837.0
USP12 -14793.0 -5995.0
USP13 -6854.0 -7443.0
USP14 -3253.0 -16676.0
USP15 -8980.0 -12354.0
USP16 -11964.0 -14784.0
USP17L2 2676.0 1546.0
USP18 -8492.0 213.0
USP19 -15104.0 -8580.0
USP2 -12462.0 -11680.0
USP20 -3830.0 -2459.0
USP21 -13801.0 -11859.0
USP22 -4318.0 -10163.0
USP24 -9879.0 -5331.0
USP25 -1523.0 -9339.0
USP28 -576.0 -16403.0
USP3 -8405.0 -11544.0
USP30 -6077.0 -8727.0
USP33 -11185.0 -9658.0
USP34 -15724.0 -7789.0
USP37 -6696.0 -2338.0
USP4 -13855.0 -10386.0
USP42 -2937.0 -2335.0
USP44 -6481.0 -3961.0
USP47 -8339.0 -5973.0
USP48 -9755.0 -11087.0
USP49 -10364.0 -8031.0
USP5 -2303.0 -14840.0
USP7 -6902.0 -2397.0
USP8 -9189.0 -6657.0
VASH1 -11723.0 -3865.0
VASH2 -896.0 -10226.0
VCAN -11870.0 -12639.0
VCP -6950.0 -13469.0
VCPIP1 -6728.0 -9063.0
VCPKMT 1074.0 -14790.0
VDAC1 -2358.0 -16357.0
VDAC2 -16360.0 -14493.0
VDAC3 -5673.0 -16259.0
VDR -10534.0 -2845.0
VGF -5208.0 -17177.0
VHL -9255.0 -285.0
VNN1 -1089.0 -5108.0
VNN2 -4704.0 -2181.0
VWA1 -8983.0 -8142.0
WAC -15217.0 -11167.0
WDR20 -3773.0 -7479.0
WDR48 -8846.0 -15062.0
WDR5 -12951.0 -3421.0
WDTC1 -4623.0 -11975.0
WFS1 -7602.0 -10055.0
WRN -10141.5 -6355.0
WSB1 -731.0 -16402.0
WSB2 -4051.0 -6180.0
XPC -12691.0 -13203.0
XRCC4 -5589.0 -14690.0
YKT6 -6900.0 -15068.0
YOD1 1918.0 -6046.0
YY1 -16108.0 -12034.0
ZBTB16 -3915.0 -3363.0
ZNF131 -16248.0 -10669.0
ZNF350 -1180.0 -5822.0
ZRANB1 -16499.0 -6215.0



REACTOME_M_PHASE

REACTOME_M_PHASE
metric value
setSize 399
pMANOVA 4.22e-09
p.adjustMANOVA 5.02e-07
s.dist 0.199
s.Estill -0.102
s.Novakovic -0.171
p.Estill 0.000458
p.Novakovic 4.8e-09




Top 20 genes
Gene Estill Novakovic
NUP37 -15153 -17285
H3C12 -15164 -17158
NUP153 -14779 -17257
MAD2L1 -14859 -17139
CDCA5 -15196 -16601
KIF23 -15518 -16131
PSMA7 -15238 -16097
SMC3 -14879 -16404
TUBG1 -16375 -14891
TUBA1B -14029 -17230
PSMD1 -15755 -15264
CENPO -14764 -16262
PPP2CA -16303 -14663
CEP135 -16264 -14394
FBXO5 -15003 -15440
NCAPH2 -16362 -13856
H2AX -13329 -16764
NUF2 -14033 -15760
PPP2R5D -13597 -16200
CEP43 -13278 -16552

Click HERE to show all gene set members

All member genes
Estill Novakovic
AAAS -5233.0 -3868.0
ACTR1A -10774.0 -9995.0
AHCTF1 -2570.0 -3624.0
AKAP9 -11760.0 -8323.0
ALMS1 -10177.0 -1025.0
ANAPC1 -2324.0 -5744.0
ANAPC10 -11343.0 -5816.0
ANAPC11 -15553.0 -3569.0
ANAPC15 -5573.0 -1354.0
ANAPC16 -3464.0 -3219.0
ANAPC2 -8367.0 -1213.0
ANAPC4 -11051.0 -6188.0
ANAPC5 -7613.0 -11860.0
ANAPC7 -6389.0 -4274.0
ANKLE2 -990.0 -8487.0
ARPP19 -15292.0 -9905.0
AURKB -585.0 -2715.0
B9D2 -6475.0 -5577.0
BANF1 -12198.0 -14222.0
BIRC5 -509.0 -2514.0
BLZF1 293.5 -15228.0
BUB1 -406.0 -13771.0
BUB1B -2372.0 -6560.0
BUB3 -3718.0 -13578.0
CC2D1B -2031.0 -14994.0
CCNB1 -15812.0 -8791.0
CCNB2 -5698.0 -12010.0
CCP110 -7242.0 -11338.0
CDC16 -3120.0 -6337.0
CDC20 -14422.0 -10269.0
CDC23 -4732.0 -5268.0
CDC26 -5432.0 -868.0
CDC27 -8038.0 -11129.0
CDCA5 -15196.0 -16601.0
CDCA8 -11699.0 -15979.0
CDK1 -629.5 -12551.0
CDK5RAP2 866.0 -2873.0
CENPA -6563.0 -11218.0
CENPC -2493.0 -14292.0
CENPE -9573.0 -14208.0
CENPF -1734.0 -5756.0
CENPH -2153.0 -17067.0
CENPJ -3229.0 -6985.0
CENPK -3128.5 -16484.0
CENPL -3296.0 -14202.0
CENPM -13815.0 -6658.0
CENPN -5955.0 -11949.0
CENPO -14764.0 -16262.0
CENPP 1162.0 -12025.0
CENPQ -313.0 -6294.0
CENPS -7432.0 -6760.0
CENPT -13891.0 -13739.0
CENPU -13118.0 -12622.0
CEP131 -3422.0 -4824.0
CEP135 -16264.0 -14394.0
CEP152 -3924.0 -12738.0
CEP164 -13.0 -12119.0
CEP192 -5821.0 -2921.0
CEP250 -7889.0 -8951.0
CEP290 -346.0 -14952.0
CEP41 -7749.0 -15982.0
CEP43 -13278.0 -16552.0
CEP57 -15253.0 -12008.0
CEP63 -12858.0 -11039.0
CEP70 -8386.0 -8265.0
CEP72 -52.0 -4610.0
CEP76 -12726.0 -16607.0
CEP78 -11770.0 -9754.0
CHMP2A -6394.0 -196.0
CHMP2B -13036.0 -15756.0
CHMP3 -7699.0 8.0
CHMP4A -8786.0 -640.0
CHMP4B -15007.0 -3831.0
CHMP4C -11740.0 -15669.0
CHMP6 -13294.0 -8756.0
CHMP7 -3337.0 -3187.0
CKAP5 -7709.0 -13566.0
CLASP1 -368.0 -10453.0
CLASP2 -14327.0 -9568.0
CLIP1 -2981.0 -8081.0
CNEP1R1 -10579.0 -7355.0
CNTRL -4976.0 -2353.0
CSNK1D -10315.0 -2827.0
CSNK1E -12689.0 -11824.0
CSNK2A1 -10932.0 -4915.0
CSNK2A2 -15748.0 -7535.0
CSNK2B -367.0 -14595.0
CTDNEP1 -7063.0 -14859.0
DCTN1 69.0 -10034.0
DCTN2 -6153.0 -1119.0
DCTN3 -12480.0 -10976.0
DSN1 -11787.0 -7717.0
DYNC1H1 48.0 -3145.0
DYNC1I1 -7317.0 -6097.0
DYNC1I2 1732.0 -12829.0
DYNC1LI1 -11159.0 -13138.0
DYNC1LI2 -12760.0 -7326.0
DYNLL1 -11160.0 -14050.0
DYNLL2 -13828.0 -13633.0
EML4 -12051.0 -11469.0
ENSA -2087.0 -5115.0
ESPL1 -8703.0 -4634.0
FBXO5 -15003.0 -15440.0
GOLGA2 -5423.0 558.0
GORASP1 -15871.0 -8506.0
GORASP2 -2113.0 -10129.0
H2AC14 -740.0 -6291.0
H2AC18 -10109.5 -16821.5
H2AC19 -10109.5 -16821.5
H2AC20 -9365.0 -421.0
H2AC4 -8682.0 -7652.0
H2AC6 -3772.0 -14402.0
H2AC7 -10309.0 -3529.5
H2AC8 -15265.0 -12472.0
H2AJ -360.0 -16792.0
H2AX -13329.0 -16764.0
H2AZ1 -10477.0 -10825.0
H2AZ2 -15177.0 -12968.0
H2BC1 930.5 1414.0
H2BC10 -12140.0 -5784.0
H2BC11 -4716.0 -15808.0
H2BC12 -3961.0 -14793.0
H2BC13 -11400.0 761.0
H2BC14 -1609.0 -8267.0
H2BC15 -2744.0 -168.0
H2BC17 -16322.0 -3166.0
H2BC21 -8996.0 -6316.0
H2BC26 -11379.0 -16861.0
H2BC3 -15205.0 -10594.0
H2BC4 -10641.0 -8955.0
H2BC5 -9533.0 315.0
H2BC6 -15206.0 266.0
H2BC7 -11776.0 -3529.5
H2BC8 -15228.0 -8541.0
H2BC9 -9951.5 -12902.5
H3-3A -13934.0 -14636.0
H3-3B -9143.0 -13971.0
H3-4 1657.0 1580.0
H3C1 -9230.0 -14629.0
H3C10 -3065.0 -374.0
H3C11 -7068.0 -13728.0
H3C12 -15164.0 -17158.0
H3C13 -4294.0 -15204.0
H3C2 -15289.0 -11553.0
H3C3 -6133.0 -14272.0
H3C4 -9971.0 -5667.0
H3C6 371.0 -17250.0
H3C7 -9951.5 -12902.5
H3C8 -15918.0 -12729.0
H4C1 -14459.0 -9617.0
H4C11 854.0 -16001.0
H4C12 -2120.0 -5312.0
H4C13 -334.0 -15402.0
H4C16 -7238.0 -8548.0
H4C2 -7763.0 -2343.0
H4C3 -5978.0 -7968.0
H4C4 -850.0 -16161.0
H4C5 -1971.0 -1886.0
H4C6 -9232.0 -16384.0
H4C8 -3484.0 -14606.0
H4C9 -10105.0 -17149.0
HAUS1 -4546.0 -13080.0
HAUS2 -13309.0 -14657.0
HAUS3 -14922.0 -6957.0
HAUS4 -13307.0 -4175.0
HAUS5 -10024.0 -12724.0
HAUS6 -5085.0 -12244.0
HAUS8 -8315.0 -10096.0
HSP90AA1 -13375.0 -9820.0
INCENP -3511.0 -5422.0
IST1 -2314.0 -15295.0
ITGB3BP -11307.0 -12811.0
KIF18A -11259.0 -13594.0
KIF20A -713.0 -7815.0
KIF23 -15518.0 -16131.0
KIF2A -3632.0 -14056.0
KIF2B 1804.0 1019.0
KIF2C -5345.0 -2415.0
KMT5A -9451.0 -10739.0
KNL1 -5912.0 -5397.0
KNTC1 1079.0 -10240.0
KPNB1 -14539.0 -12059.0
LBR -14393.0 -367.0
LEMD2 -12960.0 -11635.0
LEMD3 -4333.0 -6107.0
LMNA -8291.0 -4922.0
LMNB1 -12895.0 -9972.0
LPIN1 -236.0 -5523.0
LPIN2 -14784.0 -7501.0
LPIN3 -12097.0 49.0
MAD1L1 -2331.0 -1491.0
MAD2L1 -14859.0 -17139.0
MAPK1 -9762.0 -6238.0
MAPK3 -14286.0 -1298.0
MAPRE1 -7165.0 -1431.0
MASTL -11213.0 -7101.0
MAU2 -12852.0 -6757.0
MCPH1 -1092.0 -2898.0
MIS12 -11240.0 -17203.0
MZT1 -6708.0 -11391.0
MZT2A -11036.0 -14936.0
MZT2B -4632.0 -14385.0
NCAPD2 -2535.0 -716.0
NCAPD3 -10865.0 -11449.0
NCAPG -9210.0 -13713.0
NCAPG2 -8767.0 -6846.0
NCAPH -11798.0 -14186.0
NCAPH2 -16362.0 -13856.0
NDC1 -11478.0 -8778.0
NDC80 -4561.0 -16763.0
NDE1 -5341.0 -4338.0
NDEL1 -13160.0 -13879.0
NEDD1 -5736.0 -2444.0
NEK2 -2328.0 -10364.0
NEK6 -6875.0 -128.0
NEK7 -8135.0 -6091.0
NEK9 -10302.0 -14259.0
NINL -11999.0 -5565.0
NIPBL -13657.0 -13686.0
NME7 293.5 -7268.0
NSL1 -7434.0 -15145.0
NUDC -14374.0 -13884.0
NUF2 -14033.0 -15760.0
NUMA1 -6928.0 -6650.0
NUP107 -7236.0 -8001.0
NUP133 -2470.0 -9143.0
NUP153 -14779.0 -17257.0
NUP155 -12129.0 -15214.0
NUP160 -11625.0 -12148.0
NUP188 -7877.0 -15187.0
NUP205 -7637.0 -436.0
NUP210 -10939.0 -191.0
NUP214 -13610.0 -5777.0
NUP35 -1428.0 -7296.0
NUP37 -15153.0 -17285.0
NUP42 -8725.0 -15797.0
NUP43 -6734.0 -13552.0
NUP50 -14109.0 -5828.0
NUP54 -12929.0 -7747.0
NUP58 -9205.0 -15350.0
NUP62 -3466.0 -2332.0
NUP85 -4129.0 -11356.0
NUP88 -7189.0 -10830.0
NUP93 -3140.0 -9015.0
NUP98 -8145.0 -10870.0
ODF2 -5350.0 -8504.0
PAFAH1B1 -7252.0 -9774.0
PCM1 -9358.0 -12737.0
PCNT -6214.0 -5445.0
PDS5A -5166.0 -9013.0
PDS5B -5500.0 -6377.0
PLK1 -6031.0 -5485.0
PLK4 -7554.0 -13381.0
PMF1 -8086.0 -9424.0
POM121 -13119.0 -11642.0
POM121C -3009.0 -6792.0
PPP1CC -14817.0 -9753.0
PPP2CA -16303.0 -14663.0
PPP2CB -790.0 302.0
PPP2R1A -5112.0 -15337.0
PPP2R1B -6245.0 -9456.0
PPP2R2A -14638.0 -5917.0
PPP2R2D 1861.0 -4520.0
PPP2R5A -14844.0 -2972.0
PPP2R5B -6416.0 -16175.0
PPP2R5C -2004.0 -7658.0
PPP2R5D -13597.0 -16200.0
PPP2R5E -6877.0 -9033.0
PRKACA -15621.0 -10373.0
PRKAR2B -8749.0 -9071.0
PRKCA -1.0 -3348.0
PRKCB -1287.0 -4560.0
PSMA1 -8781.0 -2177.0
PSMA2 -7391.0 -13190.0
PSMA3 -543.0 -12585.0
PSMA4 -1489.0 -11130.0
PSMA5 -5612.0 -12086.0
PSMA6 -5453.0 -7068.0
PSMA7 -15238.0 -16097.0
PSMA8 -12998.0 1341.0
PSMB1 -7998.0 -12452.0
PSMB10 1546.0 -12645.0
PSMB11 -7675.0 461.0
PSMB2 -15087.0 -14324.0
PSMB3 -2943.0 -16574.0
PSMB4 -3092.0 -17193.0
PSMB5 -2173.0 -13304.0
PSMB6 -1270.0 -15778.0
PSMB7 1688.0 1166.0
PSMB8 251.0 -10098.0
PSMB9 -4477.0 -14712.0
PSMC1 -2414.0 -13145.0
PSMC2 -315.0 -2310.0
PSMC3 -7461.0 -17123.0
PSMC4 459.0 -4407.0
PSMC5 -9725.0 -12293.0
PSMC6 -7301.0 332.0
PSMD1 -15755.0 -15264.0
PSMD11 -6796.0 -15996.0
PSMD12 -13229.0 -1837.0
PSMD13 -9340.0 -12191.0
PSMD14 -9752.0 -14404.0
PSMD2 -5101.0 -4469.0
PSMD3 -6030.0 -12489.0
PSMD4 -6049.0 -14518.0
PSMD5 2564.0 -8724.0
PSMD6 -5979.0 -12939.0
PSMD7 -12233.0 -5710.0
PSMD8 -9781.0 -13888.0
PSMD9 -11408.0 -10645.0
PSME1 -9760.0 -16962.0
PSME2 67.0 -15711.0
PSME3 -4965.0 -13719.0
PSME4 -13130.0 -13058.0
PSMF1 -12443.0 -3758.0
PTTG1 -3508.0 -13806.0
RAB1A -11800.0 -11205.0
RAB1B -11811.0 -13124.0
RAB2A -15533.0 -5166.0
RAD21 -13034.0 -4206.0
RAE1 -10699.0 -7730.0
RAN -10662.0 -16269.0
RANBP2 -8430.0 -15721.0
RANGAP1 -7181.0 -12265.0
RB1 -9395.0 -7632.0
RCC1 -308.0 -2368.0
RCC2 -5320.0 -5307.0
RPS27 1722.0 -11381.0
RPS27A -11481.0 -2147.0
SDCCAG8 -4661.0 -3633.0
SEC13 -8604.0 -10471.0
SEH1L -8901.0 -14935.0
SEM1 -1388.0 -14801.0
SET -8737.0 -6532.0
SFI1 -12444.0 -11569.0
SGO1 -4675.0 -4366.0
SGO2 -1842.0 -8446.0
SIRT2 -6884.0 -9850.0
SKA1 -6465.0 -16444.0
SKA2 -5163.0 -5832.0
SMC2 -6739.0 -8249.0
SMC3 -14879.0 -16404.0
SMC4 -14508.0 -9211.0
SPAST -15874.0 -9503.0
SPC24 -11068.0 -15981.0
SPC25 -3265.0 -2763.0
SPDL1 -5198.0 -9012.0
SSNA1 -5964.0 -8575.0
STAG1 -4192.0 -10829.0
SUMO1 -32.0 -9758.0
TAOK1 -12592.0 -8943.0
TMPO -15535.0 -8262.0
TNPO1 -12905.0 -8329.0
TPR -12390.0 -14677.0
TUBA1A -2200.0 -6514.0
TUBA1B -14029.0 -17230.0
TUBA1C -3384.0 -9518.0
TUBA3C -2572.0 1353.0
TUBA3D 667.0 1328.0
TUBA3E -557.0 1710.0
TUBA4A -14192.0 -8929.0
TUBA4B -12730.0 -11735.0
TUBA8 -10422.0 -5063.0
TUBAL3 -1441.0 974.0
TUBB -4832.0 -14732.0
TUBB1 474.0 -2704.0
TUBB2A -9611.0 -15207.0
TUBB2B -3861.0 -15169.0
TUBB3 -8126.0 -15236.0
TUBB4A -7628.0 279.0
TUBB4B -1709.0 -4047.0
TUBB6 -10077.0 -1707.0
TUBB8 -5845.0 1599.0
TUBG1 -16375.0 -14891.0
TUBG2 -2182.0 -9317.0
TUBGCP2 -2326.0 -864.0
TUBGCP3 -11364.0 -8086.0
TUBGCP4 -14320.0 -6397.0
TUBGCP5 -5996.0 -13306.0
TUBGCP6 -5866.0 -11053.0
UBA52 -10894.0 -4996.0
UBB -12784.0 -8060.0
UBC -11566.0 -692.0
UBE2C -14095.0 -14424.0
UBE2D1 -9905.0 -15085.0
UBE2E1 -7722.0 -8346.0
UBE2I -10552.0 -5939.0
UBE2S -10702.0 -8077.0
USO1 -8214.0 -10133.0
VPS4A -6364.0 -13269.0
VRK1 -14545.0 -13800.0
VRK2 -11405.0 -3325.0
WAPL -15001.0 -14312.0
XPO1 -11418.0 -13329.0
YWHAE -7622.0 -13250.0
YWHAG -5540.0 -4226.0
ZW10 -1493.0 -10411.0
ZWILCH -15096.0 -2173.0
ZWINT -11659.0 -15238.0



REACTOME_INFECTIOUS_DISEASE

REACTOME_INFECTIOUS_DISEASE
metric value
setSize 908
pMANOVA 4.28e-09
p.adjustMANOVA 5.02e-07
s.dist 0.136
s.Estill -0.082
s.Novakovic -0.108
p.Estill 2.93e-05
p.Novakovic 3.62e-08




Top 20 genes
Gene Estill Novakovic
WASL -16155 -16794
RPL36 -15878 -16971
POLR2L -16149 -16420
MAP1LC3B -15884 -16669
NUP37 -15153 -17285
RANBP1 -15956 -16358
H3C12 -15164 -17158
IFNA8 -16402 -15852
NUP153 -14779 -17257
SEC24A -16357 -15536
SAP30L -14469 -17209
ACTB -14421 -17178
PSMA7 -15238 -16097
STAM2 -15609 -15505
TUBA1B -14029 -17230
PSMD1 -15755 -15264
DDX5 -15844 -14976
RPS5 -15070 -15693
HMGA1 -14283 -16529
SFPQ -15481 -14927

Click HERE to show all gene set members

All member genes
Estill Novakovic
AAAS -5233.0 -3868.0
ABI1 -8706.0 -514.0
ABI2 -13714.0 -9585.0
ABL1 -712.0 -2410.0
ACTB -14421.0 -17178.0
ACTG1 -14449.0 -15547.0
ACTR2 -13653.0 -16153.0
ACTR3 -13346.0 -8567.0
ADAM17 -8387.0 -13511.0
ADCY1 -10244.0 -6184.0
ADCY2 -773.0 -1492.0
ADCY3 -5312.0 -4397.0
ADCY4 -10042.0 -7235.0
ADCY5 -12569.0 -3385.0
ADCY6 -15340.0 -5491.0
ADCY7 -318.0 -2261.0
ADCY8 -12993.0 -13259.0
ADCY9 -4476.0 -156.0
ADORA2B -9344.0 -7179.0
AGRN -11173.0 -7188.0
AHCYL1 -124.0 -6922.0
AKT1 -6145.0 -2432.0
AKT2 -12142.0 -6370.0
AKT3 -835.0 -5588.0
ANO1 -5593.0 -4603.0
ANO10 -1202.0 -10445.0
ANO2 -4014.0 -4062.0
ANO3 -9206.0 -9457.0
ANO4 1018.0 -8477.0
ANO5 -14641.0 -13553.0
ANO6 -5706.0 -10679.0
ANO7 -11992.0 -2299.0
ANO8 -11638.0 -5411.0
ANO9 -2481.0 -6207.0
ANTXR1 -653.0 -9665.0
ANTXR2 -12550.0 -5698.0
AP1B1 -10843.0 -2829.0
AP1G1 -7101.0 -8593.0
AP1M1 -15618.0 -9135.0
AP1M2 -14465.0 -2057.0
AP1S1 -6598.0 -5191.0
AP1S3 -7284.0 -14594.0
AP2A1 -5528.0 -6431.0
AP2A2 -732.0 -911.0
AP2B1 -2664.0 -9219.0
AP2M1 -13282.0 -8949.0
AP2S1 669.0 -7159.0
APOBEC3G -3934.0 86.0
APP -5839.0 -4563.0
ARF1 -13286.0 -5475.0
ARID4A -4956.0 -13549.0
ARID4B -3611.0 -10009.0
ARPC1A -14578.0 -15787.0
ARPC1B -6193.0 -154.0
ARPC2 -13250.0 -6195.0
ARPC3 -4139.0 -3798.0
ARPC4 -6935.0 -14999.0
ARPC5 -12867.0 -9217.0
ATG14 -132.0 -11455.0
ATP1A1 -7980.0 -12561.0
ATP1A2 -12152.0 907.0
ATP1A3 -14271.0 -5987.0
ATP1A4 2003.0 -1178.0
ATP1B1 -6152.0 -5490.0
ATP1B2 -560.0 -16255.0
ATP1B3 -8891.0 -1048.0
ATP6V1H -12053.0 -13165.0
B2M -9736.0 -1528.0
BAIAP2 -8454.0 -5711.0
BANF1 -12198.0 -14222.0
BCL2L1 -9721.0 -12866.0
BECN1 -3483.0 -10723.0
BLNK 2293.0 -4019.0
BRD4 -1190.0 366.0
BRK1 -16103.0 -14001.0
BRMS1 -8697.0 -9571.0
BST2 -10555.0 -642.0
BTRC -8741.0 -7184.0
C3 -3487.0 -4048.0
C3AR1 1676.0 1588.0
CALM1 -11935.0 -10428.0
CALR -6453.0 -8798.0
CANX -15020.0 -1402.0
CASP1 -2020.0 -1042.0
CAV1 -6955.0 -12026.0
CBL -10152.0 -1539.0
CBLL1 -9817.0 -14070.0
CBX1 -388.0 -6360.0
CCNH -7680.0 -16219.0
CCNK -13936.0 -16492.0
CCNT1 -3658.0 -12061.0
CCNT2 -1647.0 -12723.0
CCR5 506.0 -10002.0
CD163 2295.0 -8049.0
CD247 -4987.0 -4081.0
CD28 2390.0 -8897.0
CD3G -610.0 -13183.0
CD4 -1950.0 -3627.0
CD79A -3119.0 -3408.0
CD79B -13423.0 -3130.0
CD8B -36.0 -6692.0
CD9 -845.0 -8917.0
CDC42 -1305.0 -2530.0
CDH1 -2667.0 -6402.0
CDK7 -11455.0 -8357.0
CDK9 -3604.0 -16780.0
CEBPD -15887.0 -12765.0
CHD3 -3938.0 -1979.0
CHD4 -7292.0 -147.0
CHMP1A -5729.0 -9933.0
CHMP2A -6394.0 -196.0
CHMP2B -13036.0 -15756.0
CHMP3 -7699.0 8.0
CHMP4A -8786.0 -640.0
CHMP4B -15007.0 -3831.0
CHMP4C -11740.0 -15669.0
CHMP5 -8528.0 -14898.0
CHMP6 -13294.0 -8756.0
CHMP7 -3337.0 -3187.0
CHUK -2382.0 -14034.0
CLTA -8516.0 -11275.0
CLTC -12307.0 -12603.0
CNBP -15797.0 -14505.0
COMT -9986.0 -5211.0
CORO1A -13881.0 -9999.0
CPSF4 -8835.0 -13204.0
CRB3 -15700.0 -11470.0
CRBN -12316.0 -15386.0
CREB1 -16059.0 -6298.0
CREBBP 522.0 -5671.0
CRK -13953.0 -11406.0
CSNK1A1 -11088.0 -12263.0
CTDP1 -410.0 -6290.0
CTNNB1 -16336.0 -12572.0
CTNND1 -297.0 -5319.0
CTSG -1839.0 1031.0
CTSL -10007.0 -17179.0
CUL3 -14992.0 -6223.0
CUL5 -843.0 -13119.0
CXCR4 -11164.0 -11871.0
CYBA -9733.0 -9459.0
CYFIP1 -174.0 -5190.0
CYFIP2 -5933.0 -6663.0
CYSLTR2 -4206.0 1081.0
DAD1 -4243.0 -11329.0
DAXX -5751.0 -1962.0
DDOST -854.0 -14456.0
DDX20 -7485.0 -16997.0
DDX5 -15844.0 -14976.0
DNAJC3 -7188.0 -13765.0
DOCK1 -3907.0 -5771.0
DOCK2 1499.0 -5183.0
DPEP1 -5117.0 -7678.0
DPEP2 -12818.0 -4097.0
DPEP3 -3458.0 -9342.0
DUSP16 -13032.0 -11617.0
DVL1 -4354.0 -742.0
DVL2 -12133.0 183.0
DVL3 -3044.0 -11951.0
DYNC1H1 48.0 -3145.0
DYNC1I1 -7317.0 -6097.0
DYNC1I2 1732.0 -12829.0
DYNC1LI1 -11159.0 -13138.0
DYNC1LI2 -12760.0 -7326.0
DYNLL1 -11160.0 -14050.0
DYNLL2 -13828.0 -13633.0
EDEM2 -10833.0 -8874.0
EED -10652.0 -4813.0
EEF1A1 -7263.0 -14577.0
EEF2 -12638.0 -4822.0
EGFR -4785.0 -1340.0
EIF2AK2 -13138.0 -4247.0
ELL -7312.0 -5309.0
ELMO1 -2322.0 -2306.0
ELMO2 -15503.0 -10311.0
ELOA -12870.0 -15681.0
ELOA2 2395.0 71.0
ELOB -10647.0 -14069.0
ELOC -661.0 -10616.0
ENO1 -13641.0 -10234.0
ENTPD1 -3532.0 -1284.0
ENTPD5 -12626.0 -12262.0
EP300 -1567.0 -10732.0
EPS15 -5572.0 -13129.0
ERCC2 -6567.0 -8284.0
ERCC3 -5594.0 1083.0
EZH2 -5256.0 -15114.0
FAU -8361.0 -15762.0
FCGR1A 2487.0 253.0
FCGR2A -6186.0 -81.0
FCGR3A -16251.0 1513.0
FEN1 -3850.0 -9060.0
FGR -7897.0 -2680.0
FKBP1A -6123.0 -10120.0
FKBP4 -11397.0 -14655.0
FNTA -15247.0 -12298.0
FNTB -6304.0 -19.0
FURIN -10334.0 -10318.0
FUT8 -14461.0 -10268.0
FXYD1 -8324.0 -5955.0
FXYD2 -3407.0 550.0
FXYD3 -11103.0 -1217.0
FXYD4 -2542.0 -5019.0
FXYD6 -12195.0 -667.0
FXYD7 -3740.0 -14457.0
FYN -763.0 -10108.0
FZD7 -9554.0 -17112.0
G3BP1 -14273.0 -16035.0
G3BP2 -16406.0 -13661.0
GALNT1 -9148.0 -4498.0
GANAB -8243.0 -5160.0
GATAD2A -9795.0 -3375.0
GATAD2B -8455.0 -443.0
GEMIN4 -15080.0 -231.0
GEMIN5 -7199.0 -15040.0
GEMIN6 -10776.0 -4730.0
GEMIN7 -3682.0 -906.0
GGT1 -14443.0 -9698.0
GGT5 -15528.0 -5940.0
GJA1 -1831.0 -10110.0
GNAI1 -10176.0 -15718.0
GNAI2 -12326.0 -7775.0
GNAI3 -9610.0 -9676.0
GNAS -11966.0 -7094.0
GNAZ -6402.0 -5870.0
GNB1 -5413.0 -5802.0
GNB2 -9058.0 -13745.0
GNB3 -8840.0 -5034.0
GNB4 -11543.0 -16007.0
GNB5 -5461.0 -7062.0
GNG10 1581.0 -17259.0
GNG11 -13979.0 -5482.0
GNG12 -1369.0 -7785.0
GNG13 -5498.0 -8674.0
GNG2 -775.0 -14244.0
GNG3 -12823.0 -13523.0
GNG4 -2449.0 -5221.0
GNG5 -14772.5 -8762.0
GNG7 -6771.0 -3465.0
GNG8 -954.0 -1283.0
GNGT1 -16495.0 926.0
GNGT2 -9685.0 -4859.0
GOLGA7 -7384.0 -13229.0
GPC1 -11109.0 -7559.0
GPC2 -11132.0 -11236.0
GPC5 -15441.0 -6932.0
GPC6 -3948.0 -2826.0
GPS2 -1744.0 -12885.0
GRB2 -2312.0 -10356.0
GRSF1 -15453.0 -10592.0
GSDMD -3091.0 -10111.0
GSK3A -12174.0 -10805.0
GSK3B -13275.0 -5625.0
GTF2A1 -6836.0 -12317.0
GTF2A2 -1375.0 -14599.0
GTF2B 1347.0 530.0
GTF2E1 -3851.0 -5666.0
GTF2E2 -14763.0 -7061.0
GTF2F1 -4222.0 -13948.0
GTF2F2 -12677.0 -7911.0
GTF2H1 -6201.0 -14095.0
GTF2H3 -11360.0 -16525.0
GTF2H4 -2192.0 -10297.0
GTF2H5 -11128.0 -13219.0
GUCY2C -1333.0 -449.0
H2AC1 930.5 1264.0
H2AC11 -2058.0 -15953.0
H2AC12 -3552.0 -12684.0
H2AC13 -10132.0 911.0
H2AC14 -740.0 -6291.0
H2AC15 -4251.0 192.0
H2AC16 -7809.0 -5498.0
H2AC17 -16249.0 -5223.0
H2AC18 -10109.5 -16821.5
H2AC19 -10109.5 -16821.5
H2AC20 -9365.0 -421.0
H2AC21 -2528.0 -13871.0
H2AC25 -11731.0 -16147.0
H2AC4 -8682.0 -7652.0
H2AC6 -3772.0 -14402.0
H2AC7 -10309.0 -3529.5
H2AC8 -15265.0 -12472.0
H2BC1 930.5 1414.0
H2BC10 -12140.0 -5784.0
H2BC11 -4716.0 -15808.0
H2BC12 -3961.0 -14793.0
H2BC13 -11400.0 761.0
H2BC14 -1609.0 -8267.0
H2BC15 -2744.0 -168.0
H2BC17 -16322.0 -3166.0
H2BC18 -6317.0 -9201.0
H2BC21 -8996.0 -6316.0
H2BC26 -11379.0 -16861.0
H2BC3 -15205.0 -10594.0
H2BC4 -10641.0 -8955.0
H2BC5 -9533.0 315.0
H2BC6 -15206.0 266.0
H2BC7 -11776.0 -3529.5
H2BC8 -15228.0 -8541.0
H2BC9 -9951.5 -12902.5
H3C1 -9230.0 -14629.0
H3C10 -3065.0 -374.0
H3C11 -7068.0 -13728.0
H3C12 -15164.0 -17158.0
H3C13 -4294.0 -15204.0
H3C2 -15289.0 -11553.0
H3C3 -6133.0 -14272.0
H3C4 -9971.0 -5667.0
H3C6 371.0 -17250.0
H3C7 -9951.5 -12902.5
H3C8 -15918.0 -12729.0
H4C1 -14459.0 -9617.0
H4C11 854.0 -16001.0
H4C12 -2120.0 -5312.0
H4C13 -334.0 -15402.0
H4C16 -7238.0 -8548.0
H4C2 -7763.0 -2343.0
H4C3 -5978.0 -7968.0
H4C4 -850.0 -16161.0
H4C5 -1971.0 -1886.0
H4C6 -9232.0 -16384.0
H4C8 -3484.0 -14606.0
H4C9 -10105.0 -17149.0
HAVCR1 865.0 -8204.0
HBEGF -9055.0 -6266.0
HCK -12571.0 -2602.0
HDAC1 -9758.0 -7989.0
HDAC2 -13055.0 -10473.0
HDAC3 -13458.0 -14340.0
HGS -5820.0 -2466.0
HLA-A -11670.0 -15381.0
HLA-B -4883.0 -13938.0
HLA-C -7426.0 -16151.0
HLA-E -5169.0 -16076.0
HLA-F -2480.0 -12449.0
HLA-G -2729.0 -8695.0
HMG20B -2336.0 -14844.0
HMGA1 -14283.0 -16529.0
HMOX1 -10317.0 -13400.0
HNRNPA1 -12252.0 -3722.0
HNRNPK -12474.0 -14011.0
HSP90AA1 -13375.0 -9820.0
HSP90AB1 -11098.0 -973.0
HSPA1A -11140.0 -12542.0
HSPG2 -5450.0 -3105.0
IFIH1 -11275.0 -14009.0
IFNA13 -4562.0 -14887.0
IFNA14 1253.0 432.0
IFNA4 -1453.0 1889.0
IFNA7 -16501.0 1036.0
IFNA8 -16402.0 -15852.0
IFNAR1 -10034.0 -4893.0
IFNAR2 -3970.0 -17003.0
IFNGR1 -6822.0 -14452.0
IFNGR2 -12833.0 -5604.0
IKBKB -12450.0 -2197.0
IKBKE -13310.0 -8970.0
IL10 1374.0 1299.0
IL17A 1766.0 -13643.0
IL17F 2649.0 -15667.0
IL17RA -8144.0 -5351.0
IL17RC -10321.0 -2611.0
IL18 682.0 -2241.0
IL1A 1465.0 -7341.0
IL1B -5422.0 1084.0
IL1R1 1099.0 -1967.0
IL6 -14125.0 271.0
IL6R -8732.0 -8500.0
IMPDH1 -11090.0 -14647.0
IMPDH2 -14240.0 -13118.0
IPO5 -11792.0 -7660.0
IRAK2 -6602.0 -3158.0
IRF3 -13193.0 -16445.0
IRF7 -2088.0 -10856.0
ISCU -11546.0 -10289.0
ISG15 -15709.0 -3973.0
ITCH -4315.0 -7177.0
ITGA4 -15859.0 -12983.0
ITGB1 -8035.0 -14961.0
ITPR1 311.0 -8241.0
ITPR2 -10251.0 -9326.0
ITPR3 -9861.0 -4377.0
JAK1 -4343.0 -12899.0
JAK2 -1045.0 -6197.0
JAK3 -4175.0 -4810.0
JUN -12813.0 -12417.0
KDM1A -943.0 -13344.0
KEAP1 -9462.0 -12683.0
KPNA1 -15937.0 -12138.0
KPNA2 -7909.0 -14822.0
KPNA3 -15336.0 -9979.0
KPNA4 -13067.0 -8760.0
KPNA5 -4677.0 -14863.0
KPNA7 -1130.0 -4104.0
KPNB1 -14539.0 -12059.0
LARP1 40.0 -983.0
LCK -1772.0 -3483.0
LIG1 -15008.0 -2042.0
LIG4 -7548.0 -16753.0
LTF -12612.0 -11920.0
LYN -8344.0 -1989.0
MAN1B1 -11038.0 -8489.0
MAN2A1 -9110.0 -13899.0
MAP1LC3B -15884.0 -16669.0
MAP2K1 -10590.0 -9264.0
MAP2K2 -4385.0 -7553.0
MAP2K3 -14079.0 -2543.0
MAP2K4 -10277.0 -14637.0
MAP2K6 -1705.0 -7317.0
MAP2K7 -10724.0 -4933.0
MAP3K7 -6045.0 -6323.0
MAPK1 -9762.0 -6238.0
MAPK14 -13326.0 -12144.0
MAPK3 -14286.0 -1298.0
MAPK8 -10354.0 -13170.0
MASP1 2282.0 -4508.0
MASP2 -1909.0 -2227.0
MAVS -9834.0 -11447.0
MBD3 -13231.0 -466.0
MBL2 1338.0 -7122.0
MEFV -10133.0 1244.0
MET -1987.0 -12834.0
MGAT1 -6401.0 -6547.0
MGAT2 -13580.0 -16146.0
MGAT4A -12871.0 -4661.0
MGAT4B -5825.0 -8576.0
MGAT4C -5333.0 386.0
MGAT5 861.0 -1708.0
MNAT1 -2305.0 547.0
MOGS -10368.0 -16485.0
MRC1 -6731.5 -9494.0
MTA1 -6664.0 -3863.0
MTA2 -5187.0 -10678.0
MTA3 -12067.0 -12721.0
MVB12A -12706.0 -9626.0
MVB12B -4905.0 -4177.0
MYH2 -2128.0 -2271.0
MYH9 -3823.0 -1010.0
MYO10 -1990.0 -3815.0
MYO1C -12324.0 -10305.0
MYO5A -14547.0 -8670.0
MYO9B -3582.0 -2636.0
NCBP1 -9559.5 -17039.0
NCBP2 -2050.0 -13946.0
NCK1 -13196.0 -4569.0
NCKAP1 -15598.0 -13608.0
NCKAP1L 247.0 -1594.0
NCKIPSD -8595.0 -13789.0
NCOR1 -12162.0 -4890.0
NCOR2 -2181.0 -536.0
NDC1 -11478.0 -8778.0
NEDD4L -1262.0 -6491.0
NELFA -11067.0 -10631.0
NELFB -4375.0 -5089.0
NELFCD -14735.0 -10484.0
NELFE -2132.0 -7082.0
NFE2L2 -7505.0 -15009.0
NFKB1 -8018.0 -7183.0
NFKB2 -16093.0 -12134.0
NFKBIA -6781.0 -14480.0
NLRP12 -14225.0 1260.0
NLRP3 -2300.0 205.0
NMI -11742.0 -11542.0
NMT1 590.0 -3093.0
NMT2 -14307.0 -6409.0
NOD1 -394.0 -2067.0
NOD2 -2072.0 580.0
NOS2 -4827.0 -5748.0
NOXA1 -6061.0 -11196.0
NOXO1 -11525.0 384.0
NPIPB3 2150.0 1192.0
NPM1 -8015.0 460.0
NR3C1 -11555.0 -12296.0
NRP1 1486.0 -7792.0
NT5E -5428.0 -6621.0
NUP107 -7236.0 -8001.0
NUP133 -2470.0 -9143.0
NUP153 -14779.0 -17257.0
NUP155 -12129.0 -15214.0
NUP160 -11625.0 -12148.0
NUP188 -7877.0 -15187.0
NUP205 -7637.0 -436.0
NUP210 -10939.0 -191.0
NUP214 -13610.0 -5777.0
NUP35 -1428.0 -7296.0
NUP37 -15153.0 -17285.0
NUP42 -8725.0 -15797.0
NUP43 -6734.0 -13552.0
NUP50 -14109.0 -5828.0
NUP54 -12929.0 -7747.0
NUP58 -9205.0 -15350.0
NUP62 -3466.0 -2332.0
NUP85 -4129.0 -11356.0
NUP88 -7189.0 -10830.0
NUP93 -3140.0 -9015.0
NUP98 -8145.0 -10870.0
P2RX4 -1622.0 -13524.0
P2RX7 57.0 -7539.0
PABPN1 -3138.0 -3917.0
PACS1 -873.0 -3214.0
PAK2 -1043.0 -795.0
PALS1 -15502.0 -11184.0
PARP1 -5678.0 -1342.0
PARP10 -3059.0 -5412.0
PARP14 -10668.0 -8247.0
PARP16 -7903.0 -5270.0
PARP4 -13026.0 -3870.0
PARP6 -2484.0 -2237.0
PARP8 -7590.0 -15378.0
PARP9 -6399.0 -13479.0
PATJ -2678.0 -2929.0
PCBP2 -1886.0 -98.0
PDCD1 -7462.0 -2066.0
PDCD6IP -13542.0 -3859.0
PDPK1 -6969.0 -8497.0
PHF21A -10118.0 -13044.0
PIK3C3 -319.0 -7237.0
PIK3R4 1810.0 -1620.0
PKLR -14019.0 522.0
PLCG1 -16139.0 -11621.0
PLCG2 107.0 -5623.0
PLK2 -13084.0 -17131.0
PML 884.0 -927.0
POLR2A 281.0 -12598.0
POLR2B -6420.0 -12168.0
POLR2C -9988.0 -16056.0
POLR2D -5476.0 -17166.0
POLR2E -6353.0 -15885.0
POLR2F -11988.0 -11623.0
POLR2G 1063.0 -12103.0
POLR2H -12591.0 -11738.0
POLR2I -5956.0 -15772.0
POLR2J -11626.0 -4910.0
POLR2K -1330.0 590.0
POLR2L -16149.0 -16420.0
POM121 -13119.0 -11642.0
POM121C -3009.0 -6792.0
PPIA -10000.0 -12232.0
PPIB -14930.0 -14686.0
PPIG -8963.0 -4684.0
PPIH -3666.0 -9474.0
PRKACA -15621.0 -10373.0
PRKACB -6996.0 -8892.0
PRKACG -11377.0 -8915.0
PRKAR1A -5734.0 -7100.0
PRKAR1B -2609.0 -613.0
PRKAR2A -13547.0 -14987.0
PRKAR2B -8749.0 -9071.0
PRKCSH -3401.0 -8168.0
PRMT1 -3021.0 -8191.0
PSIP1 -4072.0 -16456.0
PSMA1 -8781.0 -2177.0
PSMA2 -7391.0 -13190.0
PSMA3 -543.0 -12585.0
PSMA4 -1489.0 -11130.0
PSMA5 -5612.0 -12086.0
PSMA6 -5453.0 -7068.0
PSMA7 -15238.0 -16097.0
PSMA8 -12998.0 1341.0
PSMB1 -7998.0 -12452.0
PSMB10 1546.0 -12645.0
PSMB11 -7675.0 461.0
PSMB2 -15087.0 -14324.0
PSMB3 -2943.0 -16574.0
PSMB4 -3092.0 -17193.0
PSMB5 -2173.0 -13304.0
PSMB6 -1270.0 -15778.0
PSMB7 1688.0 1166.0
PSMB8 251.0 -10098.0
PSMB9 -4477.0 -14712.0
PSMC1 -2414.0 -13145.0
PSMC2 -315.0 -2310.0
PSMC3 -7461.0 -17123.0
PSMC4 459.0 -4407.0
PSMC5 -9725.0 -12293.0
PSMC6 -7301.0 332.0
PSMD1 -15755.0 -15264.0
PSMD11 -6796.0 -15996.0
PSMD12 -13229.0 -1837.0
PSMD13 -9340.0 -12191.0
PSMD14 -9752.0 -14404.0
PSMD2 -5101.0 -4469.0
PSMD3 -6030.0 -12489.0
PSMD4 -6049.0 -14518.0
PSMD5 2564.0 -8724.0
PSMD6 -5979.0 -12939.0
PSMD7 -12233.0 -5710.0
PSMD8 -9781.0 -13888.0
PSMD9 -11408.0 -10645.0
PSME1 -9760.0 -16962.0
PSME2 67.0 -15711.0
PSME3 -4965.0 -13719.0
PSME4 -13130.0 -13058.0
PSMF1 -12443.0 -3758.0
PSTPIP1 -8774.0 -605.0
PTGES3 -8554.0 -7663.0
PTK2 -2796.0 -3127.0
PTPN11 -9705.0 -9863.0
PTPN6 -16071.0 -1802.0
PYCARD -8215.0 -16314.0
RAB5A -4972.0 -14940.0
RAB7A -4289.0 -2505.0
RAC1 -3223.0 -13385.0
RAE1 -10699.0 -7730.0
RAN -10662.0 -16269.0
RANBP1 -15956.0 -16358.0
RANBP2 -8430.0 -15721.0
RANGAP1 -7181.0 -12265.0
RB1 -9395.0 -7632.0
RBBP4 -9690.0 -15408.0
RBX1 -6001.0 -10254.0
RCAN3 -12356.0 -8264.0
RCC1 -308.0 -2368.0
RCOR1 -10479.0 -6160.0
RELA -15610.0 -9300.0
REST -8552.0 -12442.0
RHBDF2 -7718.0 -2045.0
RIGI 658.0 -13449.0
RIPK1 2218.0 -8321.0
RIPK2 -16417.0 -13521.0
RIPK3 -5263.0 -2291.0
RNF135 2465.0 -12124.0
RNF213 521.0 -3454.0
RNGTT -13776.0 -3113.0
RNMT -12479.0 -16072.0
ROCK1 -8596.0 -6986.0
ROCK2 -15290.0 -11572.0
RPL10A -4327.0 -16688.0
RPL10L -4672.0 1242.0
RPL11 -7730.0 -11362.0
RPL12 -1818.0 -7657.0
RPL13 -13096.0 -17048.0
RPL13A -1938.5 -10955.5
RPL14 -8334.0 -15519.0
RPL15 -13598.0 -15972.0
RPL17 -4720.0 -15113.0
RPL18 -6084.0 -16405.0
RPL18A -13854.0 -12314.0
RPL19 -9925.0 -950.0
RPL21 -9899.5 -13500.5
RPL22 -2661.0 -13474.0
RPL22L1 -2679.0 -16975.0
RPL23 -3278.0 -4599.0
RPL23A -8489.0 -13877.0
RPL24 813.0 329.0
RPL26 -7851.0 -14206.0
RPL26L1 -4159.0 -17223.0
RPL27 -10972.0 -14660.0
RPL27A -11040.0 -16640.0
RPL28 -7060.0 -12491.0
RPL29 -6766.0 -14551.0
RPL3 -4433.0 -6744.0
RPL30 -3473.0 -13276.0
RPL31 160.0 -9807.0
RPL32 -8290.0 -7245.0
RPL34 -3639.0 913.0
RPL35 -12031.0 -16424.0
RPL35A -563.0 -483.0
RPL36 -15878.0 -16971.0
RPL36AL -12581.0 -15545.0
RPL37 -5636.0 -11980.0
RPL37A -8914.0 -12749.0
RPL38 -3414.0 -3066.0
RPL39L -2329.0 -16531.0
RPL3L -13013.0 328.0
RPL4 -7696.0 199.0
RPL41 -8377.0 -15742.0
RPL5 1478.0 -13656.0
RPL6 718.0 -2953.0
RPL7 -11616.0 -15741.0
RPL7A -11184.0 -3709.0
RPL8 -16023.0 -13701.0
RPL9 -4066.0 -291.0
RPLP0 -7445.0 -14511.0
RPLP1 -5049.0 -3663.0
RPLP2 -14824.0 -14743.0
RPN1 -12573.0 -5768.0
RPN2 -7951.0 -10026.0
RPS10 -11363.0 -14602.0
RPS11 -12666.0 -8009.0
RPS12 -5554.0 -5380.0
RPS13 541.0 -12870.0
RPS14 -14985.0 -576.0
RPS15 -11816.0 -15841.0
RPS15A 1563.0 -10896.0
RPS16 -12775.0 -13973.0
RPS17 363.0 -17286.0
RPS18 -5492.0 -6509.0
RPS19 -4848.0 -463.0
RPS2 -8403.0 -13161.0
RPS20 -9963.0 -9064.0
RPS21 -14247.0 -15846.0
RPS23 -4455.0 -10331.0
RPS24 1255.0 -3232.0
RPS25 -2544.0 -11699.0
RPS26 802.0 -7841.0
RPS27 1722.0 -11381.0
RPS27A -11481.0 -2147.0
RPS27L -9482.0 -16569.0
RPS28 -12352.0 -15277.0
RPS29 -8298.0 -16523.0
RPS3 1404.0 -10369.0
RPS3A -10279.0 -15494.0
RPS5 -15070.0 -15693.0
RPS6 -16407.0 -6799.0
RPS7 -3124.0 -12481.0
RPS8 -9073.0 -1281.0
RPS9 -11982.0 -623.0
RPSA -4693.0 -3295.0
RUNX1 -12963.0 -2650.0
S1PR1 -6032.0 -16704.0
SAP18 -8346.0 -9242.0
SAP30 -13513.0 -16731.0
SAP30L -14469.0 -17209.0
SAR1B -10092.0 -10733.0
SDC1 -14370.0 -9666.0
SDC2 -5455.0 -13416.0
SDC3 -14944.0 -13897.0
SDC4 -7190.0 -3608.0
SEC13 -8604.0 -10471.0
SEC23A -5849.0 -15631.0
SEC24A -16357.0 -15536.0
SEC24B -6910.0 -14357.0
SEC24C -12285.0 -2295.0
SEC24D -12021.0 -10149.0
SEH1L -8901.0 -14935.0
SEM1 -1388.0 -14801.0
SERPINE1 -5106.0 -3875.0
SFN -14353.0 255.0
SFPQ -15481.0 -14927.0
SFTPD -1654.0 1423.0
SH3GL1 -10569.0 -5139.0
SH3GL2 -11052.0 -13260.0
SH3GL3 -6505.0 -8774.0
SIGMAR1 -7288.0 -17188.0
SIKE1 -11951.0 -11989.0
SKP1 -9613.0 -15257.0
SLC25A4 -13503.0 -15246.0
SMAD3 -1318.0 -4572.0
SMAD4 -11918.0 -15024.0
SMN1 -15845.5 1558.5
SMN2 -15845.5 1558.5
SNAP25 -9473.0 -7724.0
SNF8 -8678.0 -6264.0
SNRPB -927.0 -684.0
SNRPD1 -6663.0 -17082.0
SNRPD2 -5707.0 -10042.0
SNRPD3 1994.0 -13738.0
SNRPE -6157.0 -1244.0
SNRPF -12336.0 -12075.0
SNRPG -15044.0 -13747.0
SOS1 -10061.0 -5272.0
SP1 -6339.0 -10024.0
SRC -8945.0 -2260.0
SRPK1 -11301.0 463.0
SRPK2 -5047.0 -5497.0
SSRP1 -5354.0 -4346.0
ST3GAL1 -472.0 -5959.0
ST3GAL2 -6148.0 -8627.0
ST3GAL3 365.0 -3381.0
ST3GAL4 -2005.0 -7956.0
ST6GAL1 1439.0 -3948.0
ST6GALNAC2 -11179.0 -9196.0
ST6GALNAC3 -5712.0 -11276.0
ST6GALNAC4 -23.0 -4222.0
STAM -12935.0 -9941.0
STAM2 -15609.0 -15505.0
STAT1 -5421.0 -12068.0
STAT2 -9040.0 -13664.0
STING1 -3117.0 -5564.0
STT3A -6093.0 -15573.0
STX1A -14767.0 -5292.0
STX1B -15167.0 -7121.0
SUDS3 -12701.0 -3410.0
SUGT1 -15600.0 -14724.0
SUMO1 -32.0 -9758.0
SUPT16H -9317.0 -5433.0
SUPT4H1 -12733.0 -17205.0
SUPT5H -12113.0 -11711.0
SUZ12 -12029.0 -10907.0
SV2A 205.0 -9677.0
SV2B -7289.0 -1547.0
SV2C -4249.0 -8803.0
SYK -1791.0 -4396.0
SYT1 -5544.0 -9857.0
SYT2 -5229.0 -6771.0
TAB1 -10168.0 -3850.0
TAB2 -11215.0 -5704.0
TAF10 -15058.0 -15107.0
TAF11 -12624.0 -15343.0
TAF12 -9871.0 -9618.0
TAF13 -5566.0 -3630.0
TAF15 -15451.0 -13712.0
TAF1L -13645.0 -6482.0
TAF2 1567.0 -7361.0
TAF3 -8504.0 -10415.0
TAF4 -9100.0 -5425.0
TAF4B -1458.0 -1847.0
TAF5 -2237.0 -12426.0
TAF6 -2476.0 -11602.0
TAF7 -7257.0 -13845.0
TAF9 -9131.5 -16205.0
TBK1 -16234.0 -11071.0
TBL1XR1 -10122.0 -9554.0
TBP -10253.0 -16301.0
TCEA1 -8621.0 -12734.0
TGFB1 -11372.0 -5923.0
TJP1 -5993.0 -5259.0
TKFC -3715.0 -6002.0
TLR1 2511.0 1284.0
TLR2 -3109.0 -15818.0
TLR9 -11633.0 1057.0
TMPRSS2 -16067.0 -11099.0
TOMM70 -4078.0 -16306.0
TPR -12390.0 -14677.0
TRAF3 -5923.0 -4808.0
TRAF6 -13746.0 -16063.0
TRIM25 -5651.0 -16716.0
TRIM27 -1049.0 -12367.0
TRIM28 -8177.0 -13550.0
TRIM4 -8264.0 -3720.0
TSG101 308.0 -11208.0
TUBA1A -2200.0 -6514.0
TUBA1B -14029.0 -17230.0
TUBA1C -3384.0 -9518.0
TUBA3C -2572.0 1353.0
TUBA3D 667.0 1328.0
TUBA3E -557.0 1710.0
TUBA4A -14192.0 -8929.0
TUBA4B -12730.0 -11735.0
TUBA8 -10422.0 -5063.0
TUBAL3 -1441.0 974.0
TUBB -4832.0 -14732.0
TUBB1 474.0 -2704.0
TUBB2A -9611.0 -15207.0
TUBB2B -3861.0 -15169.0
TUBB3 -8126.0 -15236.0
TUBB4A -7628.0 279.0
TUBB4B -1709.0 -4047.0
TUBB6 -10077.0 -1707.0
TUBB8 -5845.0 1599.0
TUFM -10548.0 -4900.0
TUSC3 -6658.0 -12520.0
TXN -7710.0 -11678.0
TXNIP -13682.0 -15848.0
TXNRD1 -6140.0 -5110.0
TYK2 -2677.0 -8004.0
UBA52 -10894.0 -4996.0
UBAP1 -4687.0 -12109.0
UBB -12784.0 -8060.0
UBC -11566.0 -692.0
UBE2I -10552.0 -5939.0
UBE2N -9458.0 -16754.0
UBE2V1 -11998.0 -9500.0
UVRAG -3088.0 -4689.0
VAMP1 -14148.0 -12980.0
VAMP2 -15799.0 -11261.0
VAV1 -5625.0 -2451.0
VAV2 -3015.0 -1927.0
VAV3 -5662.0 -12240.0
VCP -6950.0 -13469.0
VEGFA -4254.0 -7308.0
VHL -9255.0 -285.0
VPS11 -4941.0 -14821.0
VPS16 -9507.0 -15502.0
VPS18 -2797.0 -888.0
VPS25 -1780.0 -5533.0
VPS28 -15383.0 -4833.0
VPS33A -12063.0 -8007.0
VPS33B -2999.0 -1262.0
VPS36 -13498.0 -16614.0
VPS37A -13712.0 -12137.0
VPS37B -10905.0 -9174.0
VPS37C -12485.0 -9996.0
VPS37D -16162.0 -13504.0
VPS39 -6994.0 -7578.0
VPS41 346.0 -7411.0
VPS45 -5458.0 -11999.0
VPS4A -6364.0 -13269.0
VPS4B -6676.0 -16810.0
VTA1 -12630.0 -15941.0
WASF1 -12921.0 -838.0
WASF2 -10792.0 -4010.0
WASF3 -12387.0 -11983.0
WASL -16155.0 -16794.0
WIPF1 -3450.0 -1779.0
WIPF2 -2465.0 -10392.0
WIPF3 -3707.0 -6460.0
WNT5A -2641.0 -9466.0
XPO1 -11418.0 -13329.0
XRCC4 -5589.0 -14690.0
XRCC5 -1367.0 -12638.0
XRCC6 -10935.0 -3062.0
YES1 -2428.0 -15973.0
YWHAB -12447.0 -2244.0
YWHAE -7622.0 -13250.0
YWHAG -5540.0 -4226.0
YWHAH -15299.0 -11577.0
YWHAQ -14845.0 -8678.0
YWHAZ -11791.0 -10782.0
ZBP1 -9597.0 -1479.0
ZCRB1 -13380.0 -3405.0
ZDHHC11 -1724.0 -6926.0
ZDHHC2 -9318.0 -5908.0
ZDHHC20 -503.0 -15561.0
ZDHHC3 -10017.0 -904.0
ZDHHC5 -5211.0 -16218.0
ZDHHC8 -9259.0 -1447.0



REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA
metric value
setSize 261
pMANOVA 1.42e-08
p.adjustMANOVA 1.55e-06
s.dist 0.227
s.Estill -0.0691
s.Novakovic -0.216
p.Estill 0.0549
p.Novakovic 1.98e-09




Top 20 genes
Gene Estill Novakovic
POLR2L -16149 -16420
NUP37 -15153 -17285
NUP153 -14779 -17257
PAPOLA -16101 -15712
SNRNP40 -15294 -16098
SRSF2 -14070 -17242
DDX5 -15844 -14976
LSM7 -16128 -14627
WBP4 -15009 -15570
SF3B2 -14806 -15750
HNRNPU -15860 -14375
SRSF4 -15695 -14432
NXT1 -12398 -17072
CWC15 -13073 -16127
PPIL4 -13448 -15489
WTAP -15597 -13290
SNRPG -15044 -13747
FIP1L1 -12218 -16714
LSM3 -13185 -15226
U2SURP -13904 -14276

Click HERE to show all gene set members

All member genes
Estill Novakovic
AAAS -5233.0 -3868
ACIN1 -2538.0 -4457
ALYREF -15271.0 -5872
AQR -4043.0 -16020
BCAS2 405.0 -12934
BUD13 -15395.0 -9266
BUD31 -4516.0 -10144
C9orf78 -6006.0 -11431
CACTIN -10497.0 -9393
CASC3 -11669.0 -3656
CCAR1 -5972.0 -14379
CCDC12 -8499.0 -1155
CDC40 -12577.0 -1236
CDC5L -6296.0 -10615
CHERP -4639.0 -4769
CHTOP -9116.0 -7345
CLP1 -7232.0 -15909
CPSF1 -8024.0 -3809
CPSF2 -7994.0 -16679
CPSF3 -8471.0 -11192
CPSF4 -8835.0 -13204
CPSF6 -13603.0 -8622
CPSF7 -11225.0 -9073
CRNKL1 -5466.0 -13032
CSTF1 -7777.0 -11962
CSTF2T 263.0 -5797
CSTF3 -3210.0 -13824
CTNNBL1 -6158.0 -6087
CWC15 -13073.0 -16127
CWC22 -6853.0 -4559
CWC25 665.0 -14942
CWC27 -12578.0 -6208
CWF19L2 2306.0 -111
DDX23 -5337.0 -3147
DDX39A -7150.0 -11299
DDX41 -14171.0 -11789
DDX42 -10272.0 -11282
DDX46 -11639.0 -15837
DDX5 -15844.0 -14976
DHX15 -1546.0 -14553
DHX16 -3294.0 -13216
DHX35 -744.0 -6980
DHX38 -1782.0 -11608
DHX8 -6184.0 -6823
DHX9 -5995.0 -12772
DNAJC8 -8792.0 -4162
EFTUD2 -2765.0 -9981
EIF4A3 -30.0 -4961
EIF4E -5903.0 -11598
FAM32A -727.0 -16918
FIP1L1 -12218.0 -16714
FUS -11629.0 -1252
FYTTD1 -15501.0 -6181
GCFC2 -14194.0 -3455
GLE1 -3232.0 -7220
GPATCH1 -3252.0 -8844
GTF2F1 -4222.0 -13948
GTF2F2 -12677.0 -7911
HNRNPA1 -12252.0 -3722
HNRNPA2B1 -12846.0 -7400
HNRNPA3 -15150.0 -8362
HNRNPC -104.0 -6537
HNRNPD -9956.0 -3603
HNRNPF -11041.0 -15543
HNRNPH1 -6112.0 -10775
HNRNPK -12474.0 -14011
HNRNPL -2988.0 -17102
HNRNPM -7476.0 -3723
HNRNPR -14445.0 -11260
HNRNPU -15860.0 -14375
HSPA8 -7258.0 -2055
IK 60.0 -1920
ISY1 -7147.0 -13859
LENG1 -8666.0 -15914
LSM2 -3415.0 -4363
LSM3 -13185.0 -15226
LSM4 -12297.0 -5563
LSM5 -6024.0 -13581
LSM6 -6815.0 -9061
LSM7 -16128.0 -14627
LUC7L3 -10116.0 -14390
MAGOH -2775.0 -16629
MAGOHB -7797.0 -17140
METTL14 -7855.0 -15504
METTL3 -1285.0 -10627
MFAP1 2101.0 -7421
MTREX -15180.0 -11259
NCBP1 -9559.5 -17039
NCBP2 -2050.0 -13946
NDC1 -11478.0 -8778
NSRP1 2103.0 -8636
NUDT21 -2241.0 -14210
NUP107 -7236.0 -8001
NUP133 -2470.0 -9143
NUP153 -14779.0 -17257
NUP155 -12129.0 -15214
NUP160 -11625.0 -12148
NUP188 -7877.0 -15187
NUP205 -7637.0 -436
NUP210 -10939.0 -191
NUP214 -13610.0 -5777
NUP35 -1428.0 -7296
NUP37 -15153.0 -17285
NUP42 -8725.0 -15797
NUP43 -6734.0 -13552
NUP50 -14109.0 -5828
NUP54 -12929.0 -7747
NUP58 -9205.0 -15350
NUP62 -3466.0 -2332
NUP85 -4129.0 -11356
NUP88 -7189.0 -10830
NUP93 -3140.0 -9015
NUP98 -8145.0 -10870
NXF1 -8852.0 -11115
NXT1 -12398.0 -17072
PABPN1 -3138.0 -3917
PAPOLA -16101.0 -15712
PCBP1 -10169.0 -16427
PCBP2 -1886.0 -98
PCF11 -3445.0 -13228
PDCD7 -13540.0 -8157
PHF5A 250.0 -11085
PLRG1 -2705.0 -3336
PNN -11304.0 -12418
POLDIP3 -15594.0 -7119
POLR2A 281.0 -12598
POLR2B -6420.0 -12168
POLR2C -9988.0 -16056
POLR2D -5476.0 -17166
POLR2E -6353.0 -15885
POLR2F -11988.0 -11623
POLR2G 1063.0 -12103
POLR2H -12591.0 -11738
POLR2I -5956.0 -15772
POLR2J -11626.0 -4910
POLR2K -1330.0 590
POLR2L -16149.0 -16420
POM121 -13119.0 -11642
POM121C -3009.0 -6792
PPIE 836.0 77
PPIG -8963.0 -4684
PPIH -3666.0 -9474
PPIL1 -2175.0 -5065
PPIL2 -8250.0 -6840
PPIL3 -8510.0 -12194
PPIL4 -13448.0 -15489
PPP1R8 -1183.0 -16138
PPWD1 -3128.5 -15365
PRCC 1835.0 -3684
PRKRIP1 -6127.0 -9646
PRPF18 -113.0 -7334
PRPF19 -10166.0 -16418
PRPF3 -14854.0 -3283
PRPF31 -9151.0 -8721
PRPF38A -5974.0 -1739
PRPF4 -4269.0 -7783
PRPF40A -12872.0 -12830
PRPF6 -580.0 -4254
PRPF8 -2174.0 -6225
PTBP1 -7738.0 -7034
PUF60 -13313.0 -8685
RAE1 -10699.0 -7730
RANBP2 -8430.0 -15721
RBM17 -8943.0 -5843
RBM22 -12442.0 -10854
RBM25 -7406.0 -9102
RBM39 -3321.0 -9939
RBM42 439.0 -12508
RBM5 -336.0 -9736
RBM7 -8351.0 -7134
RBM8A -8207.0 -1247
RNPC3 -8856.0 -7199
RNPS1 -15843.0 -6534
SAP18 -8346.0 -9242
SARNP -3441.0 -1564
SART1 -1236.0 -6561
SDE2 -11312.0 -11143
SEC13 -8604.0 -10471
SEH1L -8901.0 -14935
SF1 -10586.0 -6786
SF3A1 -9477.0 -3830
SF3A2 -1539.0 -12886
SF3A3 -7627.0 -13984
SF3B1 -3327.0 -4670
SF3B2 -14806.0 -15750
SF3B3 -8037.0 -12368
SF3B4 -10782.0 -304
SF3B5 -10643.0 -4270
SLBP -10454.0 -14847
SLU7 -310.0 -11064
SMNDC1 505.0 -15061
SMU1 -1032.0 -13197
SNIP1 -222.0 -10344
SNRNP200 -9880.0 -12743
SNRNP25 -6129.0 -15241
SNRNP27 2.0 -16643
SNRNP35 -1585.0 -5122
SNRNP40 -15294.0 -16098
SNRNP48 -12705.0 -2563
SNRNP70 -412.0 -2675
SNRPA -9662.0 -5775
SNRPA1 -10965.0 -13829
SNRPB -927.0 -684
SNRPB2 -13325.0 -2526
SNRPC -10677.0 -16363
SNRPD1 -6663.0 -17082
SNRPD2 -5707.0 -10042
SNRPD3 1994.0 -13738
SNRPE -6157.0 -1244
SNRPF -12336.0 -12075
SNRPG -15044.0 -13747
SNRPN -11883.0 -827
SNU13 -4140.0 -11984
SNW1 -4711.0 -3629
SRRM1 -15455.0 -10860
SRRM2 -2803.0 -7642
SRRT 1248.0 -2644
SRSF1 -1936.0 -13625
SRSF10 -9606.0 -6278
SRSF11 -13230.0 -9481
SRSF12 -4491.0 -7612
SRSF2 -14070.0 -17242
SRSF3 -8788.0 -9919
SRSF4 -15695.0 -14432
SRSF5 -7324.0 -3316
SRSF6 -10229.0 -12794
SRSF7 -5755.0 -13406
SRSF8 -8246.0 -10864
SRSF9 -11326.0 -17076
SUGP1 -10222.0 -2277
SYF2 -3367.0 -7194
SYMPK -3587.0 -9784
TCERG1 -1377.0 -4364
TFIP11 -985.0 -14960
THOC1 -13496.0 -12931
THOC3 1025.0 -6860
THOC5 -7076.0 -13735
THOC6 -9681.0 -2837
THOC7 -15935.0 -12396
TPR -12390.0 -14677
TRA2B -5013.0 -247
TXNL4A -6925.0 -8542
U2AF1 -13274.0 -14544
U2AF1L4 -1258.0 -10948
U2AF2 -11577.0 -15695
U2SURP -13904.0 -14276
UBL5 -14675.0 -8655
USP39 -5794.0 -10070
WBP11 -808.0 -2492
WBP4 -15009.0 -15570
WDR33 -4585.0 -13497
WDR70 -10535.0 -4839
WTAP -15597.0 -13290
XAB2 -1828.0 -2889
YBX1 -14292.0 -7832
YJU2 -6260.0 -5708
ZC3H11A -6761.0 -6913
ZCRB1 -13380.0 -3405
ZMAT2 -3019.0 -11910
ZMAT5 -9196.0 -14958
ZNF830 -7829.5 -13891



REACTOME_DEFENSINS

REACTOME_DEFENSINS
metric value
setSize 41
pMANOVA 2.56e-08
p.adjustMANOVA 2.55e-06
s.dist 0.592
s.Estill 0.341
s.Novakovic 0.484
p.Estill 0.000161
p.Novakovic 8e-08




Top 20 genes
Gene Estill Novakovic
DEFB107A 2598.5 1795.5
DEFB107B 2598.5 1795.5
DEFB108B 2344.0 1629.0
TLR1 2511.0 1284.0
DEFB119 1643.0 1432.0
DEFA6 1507.0 941.0
DEFB118 672.0 1474.0
CCR2 803.0 1211.0

Click HERE to show all gene set members

All member genes
Estill Novakovic
ART1 -4686.0 -12705.0
CCR2 803.0 1211.0
CCR6 -1100.0 -957.0
CD4 -1950.0 -3627.0
DEFA1 -10502.5 1731.5
DEFA1B -10502.5 1731.5
DEFA3 -15955.0 1682.0
DEFA4 -8431.0 845.0
DEFA5 -4268.0 -11694.0
DEFA6 1507.0 941.0
DEFB1 -615.0 268.0
DEFB104A 935.5 -12213.5
DEFB104B 935.5 -12213.5
DEFB105A 1628.5 -1143.5
DEFB105B 1628.5 -1143.5
DEFB106A -428.5 -11168.5
DEFB106B -428.5 -11168.5
DEFB107A 2598.5 1795.5
DEFB107B 2598.5 1795.5
DEFB108B 2344.0 1629.0
DEFB115 -4185.0 -777.0
DEFB116 -11320.0 513.0
DEFB118 672.0 1474.0
DEFB119 1643.0 1432.0
DEFB121 -1563.0 -4576.0
DEFB123 -11869.0 1547.0
DEFB124 -5916.0 -515.0
DEFB125 -2711.0 1689.0
DEFB126 2588.0 -6168.0
DEFB127 539.0 -299.0
DEFB128 1601.0 -5013.0
DEFB129 2437.0 -6648.0
DEFB131A -14407.0 -1462.0
DEFB132 -13625.0 518.0
DEFB133 -16387.0 1494.0
DEFB134 -14899.0 -10385.0
DEFB135 650.0 -1392.0
DEFB136 -6556.0 -15810.0
PRSS3 -10686.0 -1439.0
TLR1 2511.0 1284.0
TLR2 -3109.0 -15818.0



REACTOME_CELL_CYCLE_CHECKPOINTS

REACTOME_CELL_CYCLE_CHECKPOINTS
metric value
setSize 284
pMANOVA 2.88e-08
p.adjustMANOVA 2.55e-06
s.dist 0.215
s.Estill -0.073
s.Novakovic -0.202
p.Estill 0.0345
p.Novakovic 4.66e-09




Top 20 genes
Gene Estill Novakovic
DBF4 -15835.5 -16964
NUP37 -15153.0 -17285
MAD2L1 -14859.0 -17139
ATRIP -16346.0 -15271
PSMA7 -15238.0 -16097
MCM4 -14468.0 -16835
PSMD1 -15755.0 -15264
CENPO -14764.0 -16262
CCNE1 -14226.0 -16873
PPP2CA -16303.0 -14663
TOPBP1 -14077.0 -16364
NBN -14657.0 -15359
H2AX -13329.0 -16764
NUF2 -14033.0 -15760
PPP2R5D -13597.0 -16200
PSMB2 -15087.0 -14324
CDKN1B -15950.0 -12998
UBE2C -14095.0 -14424
NUDC -14374.0 -13884
WEE1 -13550.0 -14529

Click HERE to show all gene set members

All member genes
Estill Novakovic
ABRAXAS1 -9135.0 -15398.0
AHCTF1 -2570.0 -3624.0
ANAPC1 -2324.0 -5744.0
ANAPC10 -11343.0 -5816.0
ANAPC11 -15553.0 -3569.0
ANAPC15 -5573.0 -1354.0
ANAPC16 -3464.0 -3219.0
ANAPC2 -8367.0 -1213.0
ANAPC4 -11051.0 -6188.0
ANAPC5 -7613.0 -11860.0
ANAPC7 -6389.0 -4274.0
ATM -10666.0 -3054.0
ATR -5921.0 -15232.0
ATRIP -16346.0 -15271.0
AURKB -585.0 -2715.0
B9D2 -6475.0 -5577.0
BABAM1 -7407.0 -16872.0
BABAM2 -2016.0 -4347.0
BARD1 -9780.0 -7224.0
BIRC5 -509.0 -2514.0
BLM -8164.0 -12810.0
BRCA1 2021.0 628.0
BRIP1 1640.0 -14117.0
BUB1 -406.0 -13771.0
BUB1B -2372.0 -6560.0
BUB3 -3718.0 -13578.0
CCNA1 -11907.0 -12984.0
CCNA2 -6087.0 -16501.0
CCNB1 -15812.0 -8791.0
CCNB2 -5698.0 -12010.0
CCNE1 -14226.0 -16873.0
CCNE2 -10192.0 -8331.0
CDC16 -3120.0 -6337.0
CDC20 -14422.0 -10269.0
CDC23 -4732.0 -5268.0
CDC25A -9632.0 -11288.0
CDC25C -5672.0 -11011.0
CDC26 -5432.0 -868.0
CDC27 -8038.0 -11129.0
CDC45 -6700.0 80.0
CDC6 -9764.0 -8910.0
CDC7 -9686.0 -12389.0
CDCA8 -11699.0 -15979.0
CDK1 -629.5 -12551.0
CDK2 -241.0 -10000.0
CDKN1A -7625.0 -12022.0
CDKN1B -15950.0 -12998.0
CDKN2A -13143.0 -1475.0
CENPA -6563.0 -11218.0
CENPC -2493.0 -14292.0
CENPE -9573.0 -14208.0
CENPF -1734.0 -5756.0
CENPH -2153.0 -17067.0
CENPK -3128.5 -16484.0
CENPL -3296.0 -14202.0
CENPM -13815.0 -6658.0
CENPN -5955.0 -11949.0
CENPO -14764.0 -16262.0
CENPP 1162.0 -12025.0
CENPQ -313.0 -6294.0
CENPS -7432.0 -6760.0
CENPT -13891.0 -13739.0
CENPU -13118.0 -12622.0
CHEK1 -5590.0 -8025.0
CHEK2 -2471.0 -14997.0
CKAP5 -7709.0 -13566.0
CLASP1 -368.0 -10453.0
CLASP2 -14327.0 -9568.0
CLIP1 -2981.0 -8081.0
CLSPN -6560.0 -13561.0
COP1 -12587.0 -4949.0
DBF4 -15835.5 -16964.0
DNA2 -3490.0 -12624.0
DSN1 -11787.0 -7717.0
DYNC1H1 48.0 -3145.0
DYNC1I1 -7317.0 -6097.0
DYNC1I2 1732.0 -12829.0
DYNC1LI1 -11159.0 -13138.0
DYNC1LI2 -12760.0 -7326.0
DYNLL1 -11160.0 -14050.0
DYNLL2 -13828.0 -13633.0
EXO1 -10822.0 -13991.0
GTSE1 -13342.0 -12313.0
H2AX -13329.0 -16764.0
H2BC1 930.5 1414.0
H2BC10 -12140.0 -5784.0
H2BC11 -4716.0 -15808.0
H2BC12 -3961.0 -14793.0
H2BC13 -11400.0 761.0
H2BC14 -1609.0 -8267.0
H2BC15 -2744.0 -168.0
H2BC17 -16322.0 -3166.0
H2BC21 -8996.0 -6316.0
H2BC26 -11379.0 -16861.0
H2BC3 -15205.0 -10594.0
H2BC4 -10641.0 -8955.0
H2BC5 -9533.0 315.0
H2BC6 -15206.0 266.0
H2BC7 -11776.0 -3529.5
H2BC8 -15228.0 -8541.0
H2BC9 -9951.5 -12902.5
H3-4 1657.0 1580.0
H4C1 -14459.0 -9617.0
H4C11 854.0 -16001.0
H4C12 -2120.0 -5312.0
H4C13 -334.0 -15402.0
H4C16 -7238.0 -8548.0
H4C2 -7763.0 -2343.0
H4C3 -5978.0 -7968.0
H4C4 -850.0 -16161.0
H4C5 -1971.0 -1886.0
H4C6 -9232.0 -16384.0
H4C8 -3484.0 -14606.0
H4C9 -10105.0 -17149.0
HERC2 1179.0 -69.0
HUS1 -1463.0 -13599.0
INCENP -3511.0 -5422.0
ITGB3BP -11307.0 -12811.0
KAT5 -7750.0 -6812.0
KIF18A -11259.0 -13594.0
KIF2A -3632.0 -14056.0
KIF2B 1804.0 1019.0
KIF2C -5345.0 -2415.0
KNL1 -5912.0 -5397.0
KNTC1 1079.0 -10240.0
MAD1L1 -2331.0 -1491.0
MAD2L1 -14859.0 -17139.0
MAPRE1 -7165.0 -1431.0
MCM10 -909.0 -8152.0
MCM2 -1986.0 -8659.0
MCM3 -5522.0 -10547.0
MCM4 -14468.0 -16835.0
MCM5 -1200.0 -8591.0
MCM6 -11808.0 -8449.0
MCM7 -8495.0 -8481.0
MCM8 -6147.0 -12690.0
MDC1 -2592.0 -10245.0
MDM2 -10651.0 113.0
MDM4 -1979.0 -12057.0
MIS12 -11240.0 -17203.0
MRE11 -5819.0 -3826.0
NBN -14657.0 -15359.0
NDC80 -4561.0 -16763.0
NDE1 -5341.0 -4338.0
NDEL1 -13160.0 -13879.0
NSD2 -143.0 -5226.0
NSL1 -7434.0 -15145.0
NUDC -14374.0 -13884.0
NUF2 -14033.0 -15760.0
NUP107 -7236.0 -8001.0
NUP133 -2470.0 -9143.0
NUP160 -11625.0 -12148.0
NUP37 -15153.0 -17285.0
NUP43 -6734.0 -13552.0
NUP85 -4129.0 -11356.0
NUP98 -8145.0 -10870.0
ORC1 -5516.0 -284.0
ORC2 -128.0 -11753.0
ORC3 -10220.0 -14587.0
ORC4 -14431.0 -9786.0
ORC5 -10623.0 -6933.0
ORC6 -10847.0 -16383.0
PAFAH1B1 -7252.0 -9774.0
PCBP4 -14298.0 -11847.0
PHF20 -8066.0 -3022.0
PIAS4 -11745.0 -8067.0
PKMYT1 -9650.0 -9140.0
PLK1 -6031.0 -5485.0
PMF1 -8086.0 -9424.0
PPP1CC -14817.0 -9753.0
PPP2CA -16303.0 -14663.0
PPP2CB -790.0 302.0
PPP2R1A -5112.0 -15337.0
PPP2R1B -6245.0 -9456.0
PPP2R5A -14844.0 -2972.0
PPP2R5B -6416.0 -16175.0
PPP2R5C -2004.0 -7658.0
PPP2R5D -13597.0 -16200.0
PPP2R5E -6877.0 -9033.0
PSMA1 -8781.0 -2177.0
PSMA2 -7391.0 -13190.0
PSMA3 -543.0 -12585.0
PSMA4 -1489.0 -11130.0
PSMA5 -5612.0 -12086.0
PSMA6 -5453.0 -7068.0
PSMA7 -15238.0 -16097.0
PSMA8 -12998.0 1341.0
PSMB1 -7998.0 -12452.0
PSMB10 1546.0 -12645.0
PSMB11 -7675.0 461.0
PSMB2 -15087.0 -14324.0
PSMB3 -2943.0 -16574.0
PSMB4 -3092.0 -17193.0
PSMB5 -2173.0 -13304.0
PSMB6 -1270.0 -15778.0
PSMB7 1688.0 1166.0
PSMB8 251.0 -10098.0
PSMB9 -4477.0 -14712.0
PSMC1 -2414.0 -13145.0
PSMC2 -315.0 -2310.0
PSMC3 -7461.0 -17123.0
PSMC4 459.0 -4407.0
PSMC5 -9725.0 -12293.0
PSMC6 -7301.0 332.0
PSMD1 -15755.0 -15264.0
PSMD11 -6796.0 -15996.0
PSMD12 -13229.0 -1837.0
PSMD13 -9340.0 -12191.0
PSMD14 -9752.0 -14404.0
PSMD2 -5101.0 -4469.0
PSMD3 -6030.0 -12489.0
PSMD4 -6049.0 -14518.0
PSMD5 2564.0 -8724.0
PSMD6 -5979.0 -12939.0
PSMD7 -12233.0 -5710.0
PSMD8 -9781.0 -13888.0
PSMD9 -11408.0 -10645.0
PSME1 -9760.0 -16962.0
PSME2 67.0 -15711.0
PSME3 -4965.0 -13719.0
PSME4 -13130.0 -13058.0
PSMF1 -12443.0 -3758.0
RAD1 -10349.0 -12579.0
RAD17 -9131.5 -14142.0
RAD50 -5291.0 -7668.0
RAD9A -13056.0 -11198.0
RAD9B -14660.0 -6250.0
RANBP2 -8430.0 -15721.0
RANGAP1 -7181.0 -12265.0
RBBP8 -12465.0 -15065.0
RCC2 -5320.0 -5307.0
RFC2 -11390.0 -13410.0
RFC3 1547.0 -8638.0
RFC4 -12661.0 -13699.0
RFC5 -3459.0 -7830.0
RHNO1 -10225.0 -9607.0
RMI1 -14153.0 -11854.0
RMI2 -8312.0 -8455.0
RNF168 -3627.0 -5998.0
RNF8 -13451.0 -7725.0
RPA1 1482.0 -2054.0
RPA2 -6976.0 -8172.0
RPA3 -13260.0 -8291.0
RPS27 1722.0 -11381.0
RPS27A -11481.0 -2147.0
SEC13 -8604.0 -10471.0
SEH1L -8901.0 -14935.0
SEM1 -1388.0 -14801.0
SFN -14353.0 255.0
SGO1 -4675.0 -4366.0
SGO2 -1842.0 -8446.0
SKA1 -6465.0 -16444.0
SKA2 -5163.0 -5832.0
SPC24 -11068.0 -15981.0
SPC25 -3265.0 -2763.0
SPDL1 -5198.0 -9012.0
TAOK1 -12592.0 -8943.0
TOP3A -7766.0 -4898.0
TOPBP1 -14077.0 -16364.0
TP53 -3878.0 -8153.0
TP53BP1 -461.0 -10402.0
UBA52 -10894.0 -4996.0
UBB -12784.0 -8060.0
UBC -11566.0 -692.0
UBE2C -14095.0 -14424.0
UBE2D1 -9905.0 -15085.0
UBE2E1 -7722.0 -8346.0
UBE2N -9458.0 -16754.0
UBE2S -10702.0 -8077.0
UBE2V2 -16133.0 -1676.0
UIMC1 -9235.0 -8424.0
WEE1 -13550.0 -14529.0
WRN -10141.5 -6355.0
XPO1 -11418.0 -13329.0
YWHAB -12447.0 -2244.0
YWHAE -7622.0 -13250.0
YWHAG -5540.0 -4226.0
YWHAH -15299.0 -11577.0
YWHAQ -14845.0 -8678.0
YWHAZ -11791.0 -10782.0
ZNF385A -10615.0 -5596.0
ZW10 -1493.0 -10411.0
ZWILCH -15096.0 -2173.0
ZWINT -11659.0 -15238.0



REACTOME_INFLUENZA_INFECTION

REACTOME_INFLUENZA_INFECTION
metric value
setSize 150
pMANOVA 2.9e-08
p.adjustMANOVA 2.55e-06
s.dist 0.299
s.Estill -0.121
s.Novakovic -0.274
p.Estill 0.0104
p.Novakovic 7.25e-09




Top 20 genes
Gene Estill Novakovic
RPL36 -15878 -16971
POLR2L -16149 -16420
NUP37 -15153 -17285
NUP153 -14779 -17257
RPS5 -15070 -15693
RPS21 -14247 -15846
RPL13 -13096 -17048
RPL8 -16023 -13701
RPLP2 -14824 -14743
RPL15 -13598 -15972
RPL35 -12031 -16424
RPL36AL -12581 -15545
KPNA1 -15937 -12138
RPS28 -12352 -15277
RPS15 -11816 -15841
NUP155 -12129 -15214
RPL27A -11040 -16640
RPL7 -11616 -15741
TPR -12390 -14677
RPS16 -12775 -13973

Click HERE to show all gene set members

All member genes
Estill Novakovic
AAAS -5233.0 -3868.0
CALR -6453.0 -8798.0
CANX -15020.0 -1402.0
CLTA -8516.0 -11275.0
CLTC -12307.0 -12603.0
CPSF4 -8835.0 -13204.0
DNAJC3 -7188.0 -13765.0
EIF2AK2 -13138.0 -4247.0
FAU -8361.0 -15762.0
GRSF1 -15453.0 -10592.0
GTF2F1 -4222.0 -13948.0
GTF2F2 -12677.0 -7911.0
HSP90AA1 -13375.0 -9820.0
HSPA1A -11140.0 -12542.0
IPO5 -11792.0 -7660.0
ISG15 -15709.0 -3973.0
KPNA1 -15937.0 -12138.0
KPNA2 -7909.0 -14822.0
KPNA3 -15336.0 -9979.0
KPNA4 -13067.0 -8760.0
KPNA5 -4677.0 -14863.0
KPNA7 -1130.0 -4104.0
KPNB1 -14539.0 -12059.0
NDC1 -11478.0 -8778.0
NUP107 -7236.0 -8001.0
NUP133 -2470.0 -9143.0
NUP153 -14779.0 -17257.0
NUP155 -12129.0 -15214.0
NUP160 -11625.0 -12148.0
NUP188 -7877.0 -15187.0
NUP205 -7637.0 -436.0
NUP210 -10939.0 -191.0
NUP214 -13610.0 -5777.0
NUP35 -1428.0 -7296.0
NUP37 -15153.0 -17285.0
NUP42 -8725.0 -15797.0
NUP43 -6734.0 -13552.0
NUP50 -14109.0 -5828.0
NUP54 -12929.0 -7747.0
NUP58 -9205.0 -15350.0
NUP62 -3466.0 -2332.0
NUP85 -4129.0 -11356.0
NUP88 -7189.0 -10830.0
NUP93 -3140.0 -9015.0
NUP98 -8145.0 -10870.0
PABPN1 -3138.0 -3917.0
PARP1 -5678.0 -1342.0
POLR2A 281.0 -12598.0
POLR2B -6420.0 -12168.0
POLR2C -9988.0 -16056.0
POLR2D -5476.0 -17166.0
POLR2E -6353.0 -15885.0
POLR2F -11988.0 -11623.0
POLR2G 1063.0 -12103.0
POLR2H -12591.0 -11738.0
POLR2I -5956.0 -15772.0
POLR2J -11626.0 -4910.0
POLR2K -1330.0 590.0
POLR2L -16149.0 -16420.0
POM121 -13119.0 -11642.0
POM121C -3009.0 -6792.0
RAE1 -10699.0 -7730.0
RAN -10662.0 -16269.0
RANBP2 -8430.0 -15721.0
RPL10A -4327.0 -16688.0
RPL10L -4672.0 1242.0
RPL11 -7730.0 -11362.0
RPL12 -1818.0 -7657.0
RPL13 -13096.0 -17048.0
RPL13A -1938.5 -10955.5
RPL14 -8334.0 -15519.0
RPL15 -13598.0 -15972.0
RPL17 -4720.0 -15113.0
RPL18 -6084.0 -16405.0
RPL18A -13854.0 -12314.0
RPL19 -9925.0 -950.0
RPL21 -9899.5 -13500.5
RPL22 -2661.0 -13474.0
RPL22L1 -2679.0 -16975.0
RPL23 -3278.0 -4599.0
RPL23A -8489.0 -13877.0
RPL24 813.0 329.0
RPL26 -7851.0 -14206.0
RPL26L1 -4159.0 -17223.0
RPL27 -10972.0 -14660.0
RPL27A -11040.0 -16640.0
RPL28 -7060.0 -12491.0
RPL29 -6766.0 -14551.0
RPL3 -4433.0 -6744.0
RPL30 -3473.0 -13276.0
RPL31 160.0 -9807.0
RPL32 -8290.0 -7245.0
RPL34 -3639.0 913.0
RPL35 -12031.0 -16424.0
RPL35A -563.0 -483.0
RPL36 -15878.0 -16971.0
RPL36AL -12581.0 -15545.0
RPL37 -5636.0 -11980.0
RPL37A -8914.0 -12749.0
RPL38 -3414.0 -3066.0
RPL39L -2329.0 -16531.0
RPL3L -13013.0 328.0
RPL4 -7696.0 199.0
RPL41 -8377.0 -15742.0
RPL5 1478.0 -13656.0
RPL6 718.0 -2953.0
RPL7 -11616.0 -15741.0
RPL7A -11184.0 -3709.0
RPL8 -16023.0 -13701.0
RPL9 -4066.0 -291.0
RPLP0 -7445.0 -14511.0
RPLP1 -5049.0 -3663.0
RPLP2 -14824.0 -14743.0
RPS10 -11363.0 -14602.0
RPS11 -12666.0 -8009.0
RPS12 -5554.0 -5380.0
RPS13 541.0 -12870.0
RPS14 -14985.0 -576.0
RPS15 -11816.0 -15841.0
RPS15A 1563.0 -10896.0
RPS16 -12775.0 -13973.0
RPS17 363.0 -17286.0
RPS18 -5492.0 -6509.0
RPS19 -4848.0 -463.0
RPS2 -8403.0 -13161.0
RPS20 -9963.0 -9064.0
RPS21 -14247.0 -15846.0
RPS23 -4455.0 -10331.0
RPS24 1255.0 -3232.0
RPS25 -2544.0 -11699.0
RPS26 802.0 -7841.0
RPS27 1722.0 -11381.0
RPS27A -11481.0 -2147.0
RPS27L -9482.0 -16569.0
RPS28 -12352.0 -15277.0
RPS29 -8298.0 -16523.0
RPS3 1404.0 -10369.0
RPS3A -10279.0 -15494.0
RPS5 -15070.0 -15693.0
RPS6 -16407.0 -6799.0
RPS7 -3124.0 -12481.0
RPS8 -9073.0 -1281.0
RPS9 -11982.0 -623.0
RPSA -4693.0 -3295.0
SEC13 -8604.0 -10471.0
SEH1L -8901.0 -14935.0
TGFB1 -11372.0 -5923.0
TPR -12390.0 -14677.0
UBA52 -10894.0 -4996.0
XPO1 -11418.0 -13329.0



REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
metric value
setSize 162
pMANOVA 2.95e-08
p.adjustMANOVA 2.55e-06
s.dist 0.26
s.Estill -0.00456
s.Novakovic -0.26
p.Estill 0.92
p.Novakovic 1.09e-08




Top 20 genes
Gene Estill Novakovic
RPL36 -15878 -16971
ISL1 -15375 -16438
PSMA7 -15238 -16097
PSMD1 -15755 -15264
RPS5 -15070 -15693
RPS21 -14247 -15846
RPL13 -13096 -17048
MSI1 -13050 -16836
RPL8 -16023 -13701
RPLP2 -14824 -14743
RPL15 -13598 -15972
PSMB2 -15087 -14324
RPL35 -12031 -16424
RPL36AL -12581 -15545
RPS28 -12352 -15277
RPS15 -11816 -15841
RPL27A -11040 -16640
RPL7 -11616 -15741
RPS16 -12775 -13973
PSME4 -13130 -13058

Click HERE to show all gene set members

All member genes
Estill Novakovic
CASC3 -11669.0 -3656.0
CUL2 -3906.0 -4879.0
DAG1 -2225.0 -7816.0
EIF4A3 -30.0 -4961.0
EIF4G1 -1656.0 -6170.0
ELOB -10647.0 -14069.0
ELOC -661.0 -10616.0
ETF1 -9521.0 -10565.0
FAU -8361.0 -15762.0
GSPT1 -12163.0 -2538.0
HOXA2 1661.0 -8934.0
ISL1 -15375.0 -16438.0
LDB1 -7790.0 -15978.0
LHX2 -4692.0 -4844.0
LHX3 -5032.0 -14031.0
LHX4 -7545.0 -5614.0
LHX9 -12221.0 -12430.0
MAGOH -2775.0 -16629.0
MAGOHB -7797.0 -17140.0
MSI1 -13050.0 -16836.0
NCBP1 -9559.5 -17039.0
NCBP2 -2050.0 -13946.0
PABPC1 -6557.0 -12965.0
PSMA1 -8781.0 -2177.0
PSMA2 -7391.0 -13190.0
PSMA3 -543.0 -12585.0
PSMA4 -1489.0 -11130.0
PSMA5 -5612.0 -12086.0
PSMA6 -5453.0 -7068.0
PSMA7 -15238.0 -16097.0
PSMA8 -12998.0 1341.0
PSMB1 -7998.0 -12452.0
PSMB10 1546.0 -12645.0
PSMB11 -7675.0 461.0
PSMB2 -15087.0 -14324.0
PSMB3 -2943.0 -16574.0
PSMB4 -3092.0 -17193.0
PSMB5 -2173.0 -13304.0
PSMB6 -1270.0 -15778.0
PSMB7 1688.0 1166.0
PSMB8 251.0 -10098.0
PSMB9 -4477.0 -14712.0
PSMC1 -2414.0 -13145.0
PSMC2 -315.0 -2310.0
PSMC3 -7461.0 -17123.0
PSMC4 459.0 -4407.0
PSMC5 -9725.0 -12293.0
PSMC6 -7301.0 332.0
PSMD1 -15755.0 -15264.0
PSMD11 -6796.0 -15996.0
PSMD12 -13229.0 -1837.0
PSMD13 -9340.0 -12191.0
PSMD14 -9752.0 -14404.0
PSMD2 -5101.0 -4469.0
PSMD3 -6030.0 -12489.0
PSMD4 -6049.0 -14518.0
PSMD5 2564.0 -8724.0
PSMD6 -5979.0 -12939.0
PSMD7 -12233.0 -5710.0
PSMD8 -9781.0 -13888.0
PSMD9 -11408.0 -10645.0
PSME1 -9760.0 -16962.0
PSME2 67.0 -15711.0
PSME3 -4965.0 -13719.0
PSME4 -13130.0 -13058.0
PSMF1 -12443.0 -3758.0
RBM8A -8207.0 -1247.0
RBX1 -6001.0 -10254.0
RNPS1 -15843.0 -6534.0
ROBO1 -7350.0 -6372.0
ROBO2 -2751.0 -3170.0
ROBO3 -10190.0 -10095.0
RPL10A -4327.0 -16688.0
RPL10L -4672.0 1242.0
RPL11 -7730.0 -11362.0
RPL12 -1818.0 -7657.0
RPL13 -13096.0 -17048.0
RPL13A -1938.5 -10955.5
RPL14 -8334.0 -15519.0
RPL15 -13598.0 -15972.0
RPL17 -4720.0 -15113.0
RPL18 -6084.0 -16405.0
RPL18A -13854.0 -12314.0
RPL19 -9925.0 -950.0
RPL21 -9899.5 -13500.5
RPL22 -2661.0 -13474.0
RPL22L1 -2679.0 -16975.0
RPL23 -3278.0 -4599.0
RPL23A -8489.0 -13877.0
RPL24 813.0 329.0
RPL26 -7851.0 -14206.0
RPL26L1 -4159.0 -17223.0
RPL27 -10972.0 -14660.0
RPL27A -11040.0 -16640.0
RPL28 -7060.0 -12491.0
RPL29 -6766.0 -14551.0
RPL3 -4433.0 -6744.0
RPL30 -3473.0 -13276.0
RPL31 160.0 -9807.0
RPL32 -8290.0 -7245.0
RPL34 -3639.0 913.0
RPL35 -12031.0 -16424.0
RPL35A -563.0 -483.0
RPL36 -15878.0 -16971.0
RPL36AL -12581.0 -15545.0
RPL37 -5636.0 -11980.0
RPL37A -8914.0 -12749.0
RPL38 -3414.0 -3066.0
RPL39L -2329.0 -16531.0
RPL3L -13013.0 328.0
RPL4 -7696.0 199.0
RPL41 -8377.0 -15742.0
RPL5 1478.0 -13656.0
RPL6 718.0 -2953.0
RPL7 -11616.0 -15741.0
RPL7A -11184.0 -3709.0
RPL8 -16023.0 -13701.0
RPL9 -4066.0 -291.0
RPLP0 -7445.0 -14511.0
RPLP1 -5049.0 -3663.0
RPLP2 -14824.0 -14743.0
RPS10 -11363.0 -14602.0
RPS11 -12666.0 -8009.0
RPS12 -5554.0 -5380.0
RPS13 541.0 -12870.0
RPS14 -14985.0 -576.0
RPS15 -11816.0 -15841.0
RPS15A 1563.0 -10896.0
RPS16 -12775.0 -13973.0
RPS17 363.0 -17286.0
RPS18 -5492.0 -6509.0
RPS19 -4848.0 -463.0
RPS2 -8403.0 -13161.0
RPS20 -9963.0 -9064.0
RPS21 -14247.0 -15846.0
RPS23 -4455.0 -10331.0
RPS24 1255.0 -3232.0
RPS25 -2544.0 -11699.0
RPS26 802.0 -7841.0
RPS27 1722.0 -11381.0
RPS27A -11481.0 -2147.0
RPS27L -9482.0 -16569.0
RPS28 -12352.0 -15277.0
RPS29 -8298.0 -16523.0
RPS3 1404.0 -10369.0
RPS3A -10279.0 -15494.0
RPS5 -15070.0 -15693.0
RPS6 -16407.0 -6799.0
RPS7 -3124.0 -12481.0
RPS8 -9073.0 -1281.0
RPS9 -11982.0 -623.0
RPSA -4693.0 -3295.0
SEM1 -1388.0 -14801.0
SLIT1 -6428.0 -99.0
SLIT2 -4349.0 -3443.0
UBA52 -10894.0 -4996.0
UBB -12784.0 -8060.0
UBC -11566.0 -692.0
UPF2 -5215.0 -9117.0
UPF3A -4036.0 -16210.0
USP33 -11185.0 -9658.0
ZSWIM8 -10772.0 -11492.0



REACTOME_DNA_REPAIR

REACTOME_DNA_REPAIR
metric value
setSize 323
pMANOVA 5.12e-08
p.adjustMANOVA 4.2e-06
s.dist 0.205
s.Estill -0.0993
s.Novakovic -0.179
p.Estill 0.00217
p.Novakovic 3.05e-08




Top 20 genes
Gene Estill Novakovic
POLR2L -16149 -16420
ATRIP -16346 -15271
ACTB -14421 -17178
XPA -16421 -14948
MBD4 -15486 -15653
POLH -14163 -16817
RCHY1 -14487 -16333
PCNA -15776 -14982
USP45 -16384 -14215
TOPBP1 -14077 -16364
NBN -14657 -15359
H2AX -13329 -16764
REV3L -15965 -13716
POLE4 -14979 -14320
APBB1 -14285 -14874
BAZ1B -14363 -14528
EME2 -13684 -15008
MSH6 -15617 -13028
H2AZ2 -15177 -12968
UNG -13262 -14664

Click HERE to show all gene set members

All member genes
Estill Novakovic
ABL1 -712.0 -2410.0
ABRAXAS1 -9135.0 -15398.0
ACD -6267.0 -6892.5
ACTB -14421.0 -17178.0
ACTL6A -9017.0 -11605.0
ACTR5 -12449.0 -5847.0
ACTR8 -7010.0 -4217.0
ADPRS -6882.0 -13155.0
ALKBH2 -8727.0 -10995.0
ALKBH3 148.0 -11204.0
ALKBH5 -7449.0 -8038.0
APBB1 -14285.0 -14874.0
APEX1 -11287.0 -16141.0
AQR -4043.0 -16020.0
ASCC1 -1537.0 -8161.0
ASCC2 -15734.0 -5173.0
ASCC3 -15707.0 -12334.0
ATM -10666.0 -3054.0
ATR -5921.0 -15232.0
ATRIP -16346.0 -15271.0
BABAM1 -7407.0 -16872.0
BABAM2 -2016.0 -4347.0
BAP1 -13602.0 -11932.0
BARD1 -9780.0 -7224.0
BAZ1B -14363.0 -14528.0
BLM -8164.0 -12810.0
BRCA1 2021.0 628.0
BRCA2 -9972.0 -9971.0
BRIP1 1640.0 -14117.0
CCNA1 -11907.0 -12984.0
CCNA2 -6087.0 -16501.0
CCNH -7680.0 -16219.0
CDK2 -241.0 -10000.0
CDK7 -11455.0 -8357.0
CENPS -7432.0 -6760.0
CHD1L -6025.0 -7104.0
CHEK1 -5590.0 -8025.0
CHEK2 -2471.0 -14997.0
CLSPN -6560.0 -13561.0
COPS2 -5715.0 -14728.0
COPS3 -14394.0 -3804.0
COPS4 -11652.0 -1767.0
COPS5 -7073.0 -4587.0
COPS6 -7846.0 -16853.0
COPS7A -10631.0 -9011.0
COPS7B -8464.0 -10839.0
COPS8 -8804.0 -4570.0
CUL4A -6621.0 -10823.0
DCLRE1A -11905.0 -8625.0
DCLRE1B -3535.0 -5931.0
DCLRE1C -8409.0 -9654.0
DDB1 -3208.0 -12221.0
DDB2 -3131.0 -10737.0
DNA2 -3490.0 -12624.0
DTL -2147.0 -10668.0
ELL -7312.0 -5309.0
EME1 -8793.0 -6853.0
EME2 -13684.0 -15008.0
EP300 -1567.0 -10732.0
ERCC1 -14874.0 -12827.0
ERCC2 -6567.0 -8284.0
ERCC3 -5594.0 1083.0
ERCC4 -3474.0 -14734.0
ERCC5 -5434.0 -10494.0
ERCC6 -2919.0 -14061.0
ERCC8 -6055.0 -4451.0
EXO1 -10822.0 -13991.0
EYA1 -5226.0 -3088.0
EYA2 -7321.0 -2507.0
EYA3 -8946.0 -6866.0
EYA4 -9422.0 -12927.0
FAAP100 -4272.0 -11933.0
FAAP20 -9751.0 -7640.0
FAAP24 -1663.0 -2732.0
FAN1 -3249.0 -7719.0
FANCA -6459.0 -9526.0
FANCC -2517.0 -6822.0
FANCD2 -11197.0 -6831.0
FANCE -3826.0 -971.0
FANCF -468.0 -2476.0
FANCG -8170.0 -16159.0
FANCI -6292.0 -15584.0
FANCL -3148.0 -2401.0
FANCM -6825.0 -8826.0
FEN1 -3850.0 -9060.0
FTO -1837.0 -7403.0
GEN1 -12647.0 -13121.0
GPS1 -14920.0 -11279.0
GTF2H1 -6201.0 -14095.0
GTF2H3 -11360.0 -16525.0
GTF2H4 -2192.0 -10297.0
GTF2H5 -11128.0 -13219.0
H2AC14 -740.0 -6291.0
H2AC18 -10109.5 -16821.5
H2AC19 -10109.5 -16821.5
H2AC20 -9365.0 -421.0
H2AC4 -8682.0 -7652.0
H2AC6 -3772.0 -14402.0
H2AC7 -10309.0 -3529.5
H2AC8 -15265.0 -12472.0
H2AJ -360.0 -16792.0
H2AX -13329.0 -16764.0
H2AZ1 -10477.0 -10825.0
H2AZ2 -15177.0 -12968.0
H2BC1 930.5 1414.0
H2BC10 -12140.0 -5784.0
H2BC11 -4716.0 -15808.0
H2BC12 -3961.0 -14793.0
H2BC13 -11400.0 761.0
H2BC14 -1609.0 -8267.0
H2BC15 -2744.0 -168.0
H2BC17 -16322.0 -3166.0
H2BC21 -8996.0 -6316.0
H2BC26 -11379.0 -16861.0
H2BC3 -15205.0 -10594.0
H2BC4 -10641.0 -8955.0
H2BC5 -9533.0 315.0
H2BC6 -15206.0 266.0
H2BC7 -11776.0 -3529.5
H2BC8 -15228.0 -8541.0
H2BC9 -9951.5 -12902.5
H3-4 1657.0 1580.0
H4C1 -14459.0 -9617.0
H4C11 854.0 -16001.0
H4C12 -2120.0 -5312.0
H4C13 -334.0 -15402.0
H4C16 -7238.0 -8548.0
H4C2 -7763.0 -2343.0
H4C3 -5978.0 -7968.0
H4C4 -850.0 -16161.0
H4C5 -1971.0 -1886.0
H4C6 -9232.0 -16384.0
H4C8 -3484.0 -14606.0
H4C9 -10105.0 -17149.0
HERC2 1179.0 -69.0
HMGN1 -5826.0 -13187.0
HUS1 -1463.0 -13599.0
INO80 -11529.0 -7208.0
INO80B -6095.0 -1931.0
INO80C -9480.0 -2787.0
INO80D 689.0 -14950.0
INO80E -12270.0 -15069.0
ISG15 -15709.0 -3973.0
ISY1 -7147.0 -13859.0
KAT5 -7750.0 -6812.0
KDM4A -7122.0 -8379.0
KDM4B -5778.0 -1619.0
KPNA2 -7909.0 -14822.0
LIG1 -15008.0 -2042.0
LIG3 -3921.0 -11739.0
LIG4 -7548.0 -16753.0
MAD2L2 -7835.0 -13801.0
MAPK8 -10354.0 -13170.0
MBD4 -15486.0 -15653.0
MCRS1 -5563.0 -2080.0
MDC1 -2592.0 -10245.0
MGMT 715.0 -4374.0
MLH1 -8071.0 -12183.0
MNAT1 -2305.0 547.0
MPG -12300.0 -11556.0
MRE11 -5819.0 -3826.0
MSH2 -13421.0 -10832.0
MSH3 -4911.0 -7721.0
MSH6 -15617.0 -13028.0
MUS81 -4048.0 -9936.0
MUTYH -6501.0 -15011.0
NBN -14657.0 -15359.0
NEIL1 -5217.0 -13133.0
NEIL2 -10049.0 -5473.0
NEIL3 -9970.0 -8866.0
NFRKB -11963.0 -7512.0
NHEJ1 -9368.0 -590.0
NPLOC4 -6167.0 -2163.0
NSD2 -143.0 -5226.0
NTHL1 -13591.0 -13819.0
OGG1 -3209.0 -12261.0
PALB2 -12055.0 -14494.0
PARG -4483.0 -5240.0
PARP1 -5678.0 -1342.0
PARP2 -13688.0 -10323.0
PAXIP1 -15566.0 -9616.0
PCLAF -7499.0 -10658.0
PCNA -15776.0 -14982.0
PIAS1 -13990.0 -3876.0
PIAS3 -4305.0 -12083.0
PIAS4 -11745.0 -8067.0
PMS2 -11439.0 -13868.0
PNKP -875.0 -7490.0
POLB -2826.0 -10425.0
POLD1 -4311.0 -6454.0
POLD2 -11066.0 470.0
POLD3 -5727.0 -13049.0
POLD4 -1289.0 -13917.0
POLE -6579.0 -2548.0
POLE2 -10276.0 -11861.0
POLE3 -7721.0 -8097.0
POLE4 -14979.0 -14320.0
POLH -14163.0 -16817.0
POLI -13489.0 -13822.0
POLK -10185.0 -477.0
POLL -5991.0 -9292.0
POLM -5262.0 -14846.0
POLN -2840.0 -2668.0
POLQ -13800.0 -6286.0
POLR2A 281.0 -12598.0
POLR2B -6420.0 -12168.0
POLR2C -9988.0 -16056.0
POLR2D -5476.0 -17166.0
POLR2E -6353.0 -15885.0
POLR2F -11988.0 -11623.0
POLR2G 1063.0 -12103.0
POLR2H -12591.0 -11738.0
POLR2I -5956.0 -15772.0
POLR2J -11626.0 -4910.0
POLR2K -1330.0 590.0
POLR2L -16149.0 -16420.0
POT1 824.0 -7508.0
PPIE 836.0 77.0
PPP4C -11782.0 -9278.0
PPP4R2 -7305.0 -15133.0
PPP5C -2043.0 -5202.0
PRKDC -3499.0 -10253.0
PRPF19 -10166.0 -16418.0
RAD1 -10349.0 -12579.0
RAD17 -9131.5 -14142.0
RAD18 -9227.0 -368.0
RAD23A -10135.0 -14209.0
RAD23B -13764.0 -7138.0
RAD50 -5291.0 -7668.0
RAD51 -1993.0 -15382.0
RAD51AP1 -71.0 -2472.0
RAD51B 760.0 -5175.0
RAD51C -9057.0 93.0
RAD51D -15461.0 -3733.0
RAD52 -1922.0 -5851.0
RAD9A -13056.0 -11198.0
RAD9B -14660.0 -6250.0
RBBP8 -12465.0 -15065.0
RBX1 -6001.0 -10254.0
RCHY1 -14487.0 -16333.0
REV1 -6649.0 -11106.0
REV3L -15965.0 -13716.0
RFC1 -11317.0 -9485.0
RFC2 -11390.0 -13410.0
RFC3 1547.0 -8638.0
RFC4 -12661.0 -13699.0
RFC5 -3459.0 -7830.0
RHNO1 -10225.0 -9607.0
RIF1 -5559.0 -9149.0
RMI1 -14153.0 -11854.0
RMI2 -8312.0 -8455.0
RNF111 -6111.0 -6826.0
RNF168 -3627.0 -5998.0
RNF4 -9599.0 -3392.0
RNF8 -13451.0 -7725.0
RPA1 1482.0 -2054.0
RPA2 -6976.0 -8172.0
RPA3 -13260.0 -8291.0
RPS27A -11481.0 -2147.0
RTEL1 -10741.0 -5615.0
RUVBL1 -10977.0 -7680.0
SEM1 -1388.0 -14801.0
SIRT6 -13805.0 -6696.0
SLX1A -2396.5 -16480.5
SLX1B -2396.5 -16480.5
SLX4 -3731.0 526.0
SMARCA5 -9298.0 -13297.0
SMUG1 -5627.0 687.0
SPIDR -897.0 -3775.0
SPRTN -6280.0 -15272.0
SUMO1 -32.0 -9758.0
SUMO2 -14037.0 -12856.0
SUMO3 -14329.0 -12467.0
TCEA1 -8621.0 -12734.0
TDG -9045.0 -13531.0
TDP1 -7595.0 -9539.0
TDP2 -8319.0 -16145.0
TERF1 -12674.0 -13108.0
TERF2 -13771.0 -2138.0
TERF2IP -9680.0 -15559.0
TFPT -9263.0 -2957.0
TIMELESS -11398.0 -9917.0
TINF2 -8141.0 -14245.0
TIPIN 203.0 -2112.0
TOP3A -7766.0 -4898.0
TOPBP1 -14077.0 -16364.0
TP53 -3878.0 -8153.0
TP53BP1 -461.0 -10402.0
TRIM25 -5651.0 -16716.0
UBA52 -10894.0 -4996.0
UBA7 -12547.0 -6664.0
UBB -12784.0 -8060.0
UBC -11566.0 -692.0
UBE2B -11942.0 -10699.0
UBE2I -10552.0 -5939.0
UBE2L6 -14498.0 -11683.0
UBE2N -9458.0 -16754.0
UBE2T -1365.0 644.0
UBE2V2 -16133.0 -1676.0
UBXN1 -9590.0 -6173.0
UFD1 -7661.0 -1409.0
UIMC1 -9235.0 -8424.0
UNG -13262.0 -14664.0
USP1 -6547.0 -15969.0
USP10 -6314.0 -9837.0
USP43 -2461.0 -7864.0
USP45 -16384.0 -14215.0
USP7 -6902.0 -2397.0
UVSSA -2265.0 -4980.0
VCP -6950.0 -13469.0
WDR48 -8846.0 -15062.0
WRN -10141.5 -6355.0
XAB2 -1828.0 -2889.0
XPA -16421.0 -14948.0
XPC -12691.0 -13203.0
XRCC1 -2781.0 -3832.0
XRCC2 -4116.0 -15960.0
XRCC3 -8656.0 -3064.0
XRCC4 -5589.0 -14690.0
XRCC5 -1367.0 -12638.0
XRCC6 -10935.0 -3062.0
YY1 -16108.0 -12034.0
ZNF830 -7829.5 -13891.0



REACTOME_BETA_DEFENSINS

REACTOME_BETA_DEFENSINS
metric value
setSize 32
pMANOVA 1.11e-07
p.adjustMANOVA 8.7e-06
s.dist 0.648
s.Estill 0.447
s.Novakovic 0.468
p.Estill 1.18e-05
p.Novakovic 4.53e-06




Top 20 genes
Gene Estill Novakovic
DEFB107A 2598.5 1795.5
DEFB107B 2598.5 1795.5
DEFB108B 2344.0 1629.0
TLR1 2511.0 1284.0
DEFB119 1643.0 1432.0
DEFB118 672.0 1474.0
CCR2 803.0 1211.0

Click HERE to show all gene set members

All member genes
Estill Novakovic
CCR2 803.0 1211.0
CCR6 -1100.0 -957.0
DEFB1 -615.0 268.0
DEFB104A 935.5 -12213.5
DEFB104B 935.5 -12213.5
DEFB105A 1628.5 -1143.5
DEFB105B 1628.5 -1143.5
DEFB106A -428.5 -11168.5
DEFB106B -428.5 -11168.5
DEFB107A 2598.5 1795.5
DEFB107B 2598.5 1795.5
DEFB108B 2344.0 1629.0
DEFB115 -4185.0 -777.0
DEFB116 -11320.0 513.0
DEFB118 672.0 1474.0
DEFB119 1643.0 1432.0
DEFB121 -1563.0 -4576.0
DEFB123 -11869.0 1547.0
DEFB124 -5916.0 -515.0
DEFB125 -2711.0 1689.0
DEFB126 2588.0 -6168.0
DEFB127 539.0 -299.0
DEFB128 1601.0 -5013.0
DEFB129 2437.0 -6648.0
DEFB131A -14407.0 -1462.0
DEFB132 -13625.0 518.0
DEFB133 -16387.0 1494.0
DEFB134 -14899.0 -10385.0
DEFB135 650.0 -1392.0
DEFB136 -6556.0 -15810.0
TLR1 2511.0 1284.0
TLR2 -3109.0 -15818.0



REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS

REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS
metric value
setSize 111
pMANOVA 1.67e-07
p.adjustMANOVA 1.25e-05
s.dist 0.321
s.Estill -0.0941
s.Novakovic -0.307
p.Estill 0.0869
p.Novakovic 2.41e-08




Top 20 genes
Gene Estill Novakovic
ATP5ME -15364.0 -15648
NDUFA6 -14150.0 -16892
COX14 -15402.0 -15339
NDUFV2 -13182.0 -16649
ETFA -13277.0 -16406
ATP5F1E -13241.0 -16442
SLC25A27 -14654.0 -14317
SCO1 -13917.0 -15055
UCP1 -13081.0 -15392
CYC1 -14875.0 -13374
SCO2 -15098.0 -13166
SURF1 -15514.0 -12618
NDUFAF5 -15596.0 -12181
ETFDH -12171.0 -15530
DMAC2L -13430.5 -13979
NDUFA3 -12400.0 -14967
COX5B -14297.0 -12160
COX11 -10902.0 -15866
ATP5PO -15532.0 -11092
ATP5F1D -12279.0 -13408

Click HERE to show all gene set members

All member genes
Estill Novakovic
ACAD9 -10540.0 -11360.0
ATP5F1A -7194.0 -13341.0
ATP5F1B -10388.0 -12106.0
ATP5F1C -8576.0 -16028.0
ATP5F1D -12279.0 -13408.0
ATP5F1E -13241.0 -16442.0
ATP5MC1 -7648.0 -15300.0
ATP5MC2 -5377.0 -4017.0
ATP5MC3 -11250.0 -11912.0
ATP5ME -15364.0 -15648.0
ATP5MF -6874.0 -7164.0
ATP5MG -5879.0 -2148.0
ATP5PB -7065.0 -16718.0
ATP5PD -10606.0 -13471.0
ATP5PF -12879.0 -10986.0
ATP5PO -15532.0 -11092.0
COA1 -6143.0 -9072.0
COQ10A -3932.0 -7027.0
COQ10B -16021.0 -8221.0
COX11 -10902.0 -15866.0
COX14 -15402.0 -15339.0
COX16 -10443.0 134.0
COX18 -14154.0 -9252.0
COX19 -8594.0 -5715.0
COX20 -9445.0 -15182.0
COX4I1 -8427.0 -17276.0
COX5A -12320.0 -13007.0
COX5B -14297.0 -12160.0
COX6A1 -2855.0 -15071.0
COX6B1 -4301.0 -9406.0
COX6C -6273.0 -2535.0
COX7A2L -12857.0 -12460.0
COX7C -11305.0 -12041.0
COX8A 1645.0 -16534.0
CYC1 -14875.0 -13374.0
CYCS -13068.0 -11301.0
DMAC2L -13430.5 -13979.0
ECSIT -5551.0 -14185.0
ETFA -13277.0 -16406.0
ETFB -4797.0 -7538.0
ETFDH -12171.0 -15530.0
LRPPRC 1909.0 -6137.0
NDUFA10 -7174.0 -14744.0
NDUFA11 -5001.0 -8180.0
NDUFA12 -3151.0 -13242.0
NDUFA13 -12987.0 -5608.0
NDUFA2 -1203.0 -680.0
NDUFA3 -12400.0 -14967.0
NDUFA4 -7632.0 -13255.0
NDUFA5 1936.0 -2847.0
NDUFA6 -14150.0 -16892.0
NDUFA7 -10191.0 -11310.0
NDUFA8 -8329.5 -4531.0
NDUFA9 -8325.0 -14355.0
NDUFAB1 -7899.0 -5537.0
NDUFAF1 -1578.0 -4840.0
NDUFAF2 -4843.0 -2830.0
NDUFAF3 -2795.0 -15109.0
NDUFAF4 -10078.0 -12078.0
NDUFAF5 -15596.0 -12181.0
NDUFAF6 -5395.0 -3518.0
NDUFAF7 -8108.0 -14716.0
NDUFB1 -7712.0 -15971.0
NDUFB10 -12869.0 -12218.0
NDUFB2 -13672.0 -6873.0
NDUFB3 -567.0 -13200.0
NDUFB4 -10415.0 -12831.0
NDUFB5 -956.0 -15790.0
NDUFB6 985.0 -527.0
NDUFB7 -8437.0 -12378.0
NDUFB8 -1760.0 -10491.0
NDUFB9 -7078.0 -6396.0
NDUFC1 -11387.0 -8669.0
NDUFC2 -4484.0 -13141.0
NDUFS1 -6870.0 -16459.0
NDUFS2 -10178.0 -1790.0
NDUFS3 -3424.0 -16573.0
NDUFS4 -151.0 -4779.0
NDUFS5 -793.0 -25.0
NDUFS6 -3812.0 -8278.0
NDUFS7 -7919.0 -12307.0
NDUFS8 -9380.0 -8911.0
NDUFV1 -6847.0 -13078.0
NDUFV2 -13182.0 -16649.0
NDUFV3 -6044.0 -14913.0
NUBPL -4480.0 -3541.0
PM20D1 1975.0 96.0
SCO1 -13917.0 -15055.0
SCO2 -15098.0 -13166.0
SDHA -2270.0 -534.0
SDHB 805.0 -13726.0
SDHC -7568.0 -16770.0
SDHD -9247.5 -11433.5
SLC25A27 -14654.0 -14317.0
SURF1 -15514.0 -12618.0
TACO1 -1219.0 -3712.0
TIMMDC1 -7103.0 -7457.0
TMEM126B -4224.0 -13249.0
TMEM186 -7550.0 -16914.0
TRAP1 -2727.0 -8701.0
UCP1 -13081.0 -15392.0
UCP2 -9494.0 -12337.0
UCP3 -3453.0 -1330.0
UQCR10 -7069.0 -17114.0
UQCR11 -4968.0 -6613.0
UQCRB -5109.0 -9427.0
UQCRC1 -1297.0 -5101.0
UQCRC2 -9513.0 -5738.0
UQCRFS1 -9449.0 -13526.0
UQCRH -4053.0 -9223.0
UQCRQ -486.0 -12784.0



REACTOME_HIV_INFECTION

REACTOME_HIV_INFECTION
metric value
setSize 223
pMANOVA 1.89e-07
p.adjustMANOVA 1.35e-05
s.dist 0.228
s.Estill -0.0741
s.Novakovic -0.215
p.Estill 0.0569
p.Novakovic 2.99e-08




Top 20 genes
Gene Estill Novakovic
POLR2L -16149 -16420
NUP37 -15153 -17285
RANBP1 -15956 -16358
NUP153 -14779 -17257
PSMA7 -15238 -16097
PSMD1 -15755 -15264
HMGA1 -14283 -16529
CCNK -13936 -16492
TAF10 -15058 -15107
SUPT4H1 -12733 -17205
VPS37D -16162 -13504
PSMB2 -15087 -14324
TAF15 -15451 -13712
SLC25A4 -13503 -15246
CHMP2B -13036 -15756
ELOA -12870 -15681
VTA1 -12630 -15941
RNMT -12479 -16072
TAF11 -12624 -15343
KPNA1 -15937 -12138

Click HERE to show all gene set members

All member genes
Estill Novakovic
AAAS -5233.0 -3868
AP1B1 -10843.0 -2829
AP1G1 -7101.0 -8593
AP1M1 -15618.0 -9135
AP1M2 -14465.0 -2057
AP1S1 -6598.0 -5191
AP1S3 -7284.0 -14594
AP2A1 -5528.0 -6431
AP2A2 -732.0 -911
AP2B1 -2664.0 -9219
AP2M1 -13282.0 -8949
AP2S1 669.0 -7159
APOBEC3G -3934.0 86
ARF1 -13286.0 -5475
ATP6V1H -12053.0 -13165
B2M -9736.0 -1528
BANF1 -12198.0 -14222
BTRC -8741.0 -7184
CCNH -7680.0 -16219
CCNK -13936.0 -16492
CCNT1 -3658.0 -12061
CCNT2 -1647.0 -12723
CCR5 506.0 -10002
CD247 -4987.0 -4081
CD28 2390.0 -8897
CD4 -1950.0 -3627
CD8B -36.0 -6692
CDK7 -11455.0 -8357
CDK9 -3604.0 -16780
CHMP2A -6394.0 -196
CHMP2B -13036.0 -15756
CHMP3 -7699.0 8
CHMP4A -8786.0 -640
CHMP4B -15007.0 -3831
CHMP4C -11740.0 -15669
CHMP5 -8528.0 -14898
CHMP6 -13294.0 -8756
CHMP7 -3337.0 -3187
CTDP1 -410.0 -6290
CUL5 -843.0 -13119
CXCR4 -11164.0 -11871
DOCK2 1499.0 -5183
ELL -7312.0 -5309
ELMO1 -2322.0 -2306
ELOA -12870.0 -15681
ELOA2 2395.0 71
ELOB -10647.0 -14069
ELOC -661.0 -10616
ERCC2 -6567.0 -8284
ERCC3 -5594.0 1083
FEN1 -3850.0 -9060
FURIN -10334.0 -10318
FYN -763.0 -10108
GTF2A1 -6836.0 -12317
GTF2A2 -1375.0 -14599
GTF2B 1347.0 530
GTF2E1 -3851.0 -5666
GTF2E2 -14763.0 -7061
GTF2F1 -4222.0 -13948
GTF2F2 -12677.0 -7911
GTF2H1 -6201.0 -14095
GTF2H3 -11360.0 -16525
GTF2H4 -2192.0 -10297
GTF2H5 -11128.0 -13219
HCK -12571.0 -2602
HLA-A -11670.0 -15381
HMGA1 -14283.0 -16529
KPNA1 -15937.0 -12138
KPNB1 -14539.0 -12059
LCK -1772.0 -3483
LIG1 -15008.0 -2042
LIG4 -7548.0 -16753
MNAT1 -2305.0 547
MVB12A -12706.0 -9626
MVB12B -4905.0 -4177
NCBP1 -9559.5 -17039
NCBP2 -2050.0 -13946
NDC1 -11478.0 -8778
NEDD4L -1262.0 -6491
NELFA -11067.0 -10631
NELFB -4375.0 -5089
NELFCD -14735.0 -10484
NELFE -2132.0 -7082
NMT1 590.0 -3093
NMT2 -14307.0 -6409
NPM1 -8015.0 460
NUP107 -7236.0 -8001
NUP133 -2470.0 -9143
NUP153 -14779.0 -17257
NUP155 -12129.0 -15214
NUP160 -11625.0 -12148
NUP188 -7877.0 -15187
NUP205 -7637.0 -436
NUP210 -10939.0 -191
NUP214 -13610.0 -5777
NUP35 -1428.0 -7296
NUP37 -15153.0 -17285
NUP42 -8725.0 -15797
NUP43 -6734.0 -13552
NUP50 -14109.0 -5828
NUP54 -12929.0 -7747
NUP58 -9205.0 -15350
NUP62 -3466.0 -2332
NUP85 -4129.0 -11356
NUP88 -7189.0 -10830
NUP93 -3140.0 -9015
NUP98 -8145.0 -10870
PACS1 -873.0 -3214
PAK2 -1043.0 -795
PDCD6IP -13542.0 -3859
POLR2A 281.0 -12598
POLR2B -6420.0 -12168
POLR2C -9988.0 -16056
POLR2D -5476.0 -17166
POLR2E -6353.0 -15885
POLR2F -11988.0 -11623
POLR2G 1063.0 -12103
POLR2H -12591.0 -11738
POLR2I -5956.0 -15772
POLR2J -11626.0 -4910
POLR2K -1330.0 590
POLR2L -16149.0 -16420
POM121 -13119.0 -11642
POM121C -3009.0 -6792
PPIA -10000.0 -12232
PSIP1 -4072.0 -16456
PSMA1 -8781.0 -2177
PSMA2 -7391.0 -13190
PSMA3 -543.0 -12585
PSMA4 -1489.0 -11130
PSMA5 -5612.0 -12086
PSMA6 -5453.0 -7068
PSMA7 -15238.0 -16097
PSMA8 -12998.0 1341
PSMB1 -7998.0 -12452
PSMB10 1546.0 -12645
PSMB11 -7675.0 461
PSMB2 -15087.0 -14324
PSMB3 -2943.0 -16574
PSMB4 -3092.0 -17193
PSMB5 -2173.0 -13304
PSMB6 -1270.0 -15778
PSMB7 1688.0 1166
PSMB8 251.0 -10098
PSMB9 -4477.0 -14712
PSMC1 -2414.0 -13145
PSMC2 -315.0 -2310
PSMC3 -7461.0 -17123
PSMC4 459.0 -4407
PSMC5 -9725.0 -12293
PSMC6 -7301.0 332
PSMD1 -15755.0 -15264
PSMD11 -6796.0 -15996
PSMD12 -13229.0 -1837
PSMD13 -9340.0 -12191
PSMD14 -9752.0 -14404
PSMD2 -5101.0 -4469
PSMD3 -6030.0 -12489
PSMD4 -6049.0 -14518
PSMD5 2564.0 -8724
PSMD6 -5979.0 -12939
PSMD7 -12233.0 -5710
PSMD8 -9781.0 -13888
PSMD9 -11408.0 -10645
PSME1 -9760.0 -16962
PSME2 67.0 -15711
PSME3 -4965.0 -13719
PSME4 -13130.0 -13058
PSMF1 -12443.0 -3758
RAC1 -3223.0 -13385
RAE1 -10699.0 -7730
RAN -10662.0 -16269
RANBP1 -15956.0 -16358
RANBP2 -8430.0 -15721
RANGAP1 -7181.0 -12265
RBX1 -6001.0 -10254
RCC1 -308.0 -2368
RNGTT -13776.0 -3113
RNMT -12479.0 -16072
RPS27A -11481.0 -2147
SEC13 -8604.0 -10471
SEH1L -8901.0 -14935
SEM1 -1388.0 -14801
SKP1 -9613.0 -15257
SLC25A4 -13503.0 -15246
SSRP1 -5354.0 -4346
SUPT16H -9317.0 -5433
SUPT4H1 -12733.0 -17205
SUPT5H -12113.0 -11711
TAF10 -15058.0 -15107
TAF11 -12624.0 -15343
TAF12 -9871.0 -9618
TAF13 -5566.0 -3630
TAF15 -15451.0 -13712
TAF1L -13645.0 -6482
TAF2 1567.0 -7361
TAF3 -8504.0 -10415
TAF4 -9100.0 -5425
TAF4B -1458.0 -1847
TAF5 -2237.0 -12426
TAF6 -2476.0 -11602
TAF7 -7257.0 -13845
TAF9 -9131.5 -16205
TBP -10253.0 -16301
TCEA1 -8621.0 -12734
TPR -12390.0 -14677
TSG101 308.0 -11208
UBA52 -10894.0 -4996
UBAP1 -4687.0 -12109
UBB -12784.0 -8060
UBC -11566.0 -692
VPS28 -15383.0 -4833
VPS37A -13712.0 -12137
VPS37B -10905.0 -9174
VPS37C -12485.0 -9996
VPS37D -16162.0 -13504
VPS4A -6364.0 -13269
VPS4B -6676.0 -16810
VTA1 -12630.0 -15941
XPO1 -11418.0 -13329
XRCC4 -5589.0 -14690
XRCC5 -1367.0 -12638
XRCC6 -10935.0 -3062



REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT

REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT
metric value
setSize 58
pMANOVA 2.75e-07
p.adjustMANOVA 1.82e-05
s.dist 0.402
s.Estill 0.00551
s.Novakovic -0.402
p.Estill 0.942
p.Novakovic 1.2e-07




Top 20 genes
Gene Estill Novakovic
PITRM1 1799 -6672
FXN 751 -13268

Click HERE to show all gene set members

All member genes
Estill Novakovic
ACO2 -1344.0 -9099.0
ATP5F1A -7194.0 -13341.0
ATP5F1B -10388.0 -12106.0
ATP5MC1 -7648.0 -15300.0
BCS1L -2333.0 -4382.0
CHCHD10 -14336.0 -15876.0
CHCHD2 -12643.0 -16027.0
CHCHD3 -3761.0 -4536.0
CHCHD4 -9648.0 -13766.0
CHCHD5 -3837.0 -16651.0
CHCHD7 -7255.0 -13883.0
CMC2 -9893.0 -5155.0
COA4 -10408.0 -15538.0
COA6 -11279.0 -10181.0
COQ2 -5657.0 -13067.0
COX17 -8332.0 -4054.0
COX19 -8594.0 -5715.0
CS -1189.0 -1013.0
CYC1 -14875.0 -13374.0
DNAJC19 -6670.0 -15854.0
FXN 751.0 -13268.0
GFER -10189.0 -13428.0
GRPEL1 -11037.0 -17065.0
GRPEL2 -13816.0 -12989.0
HSCB -2836.0 -14965.0
HSPA9 -8922.0 -16233.0
HSPD1 -13321.5 -16379.0
LDHD -1013.0 -6466.0
MTX1 -4557.0 -13063.0
MTX2 -15332.0 -13752.0
NDUFB8 -1760.0 -10491.0
PAM16 -13353.0 -7351.0
PITRM1 1799.0 -6672.0
PMPCA -4296.0 -3395.0
PMPCB -3160.0 -15898.0
SAMM50 -14183.0 -11794.0
SLC25A12 -7658.0 -14977.0
SLC25A13 -8718.0 -4118.0
SLC25A4 -13503.0 -15246.0
TIMM10 -5609.0 -8019.0
TIMM10B -4770.0 -16645.0
TIMM13 -3370.0 -16331.0
TIMM17A -423.0 -9545.0
TIMM21 -931.0 -8289.0
TIMM22 -14820.0 -17059.0
TIMM23 -7885.0 -12419.0
TIMM44 -9163.0 -8316.0
TIMM50 -1997.0 -8656.0
TIMM8B -9247.5 -11433.5
TIMM9 -925.0 -4371.0
TOMM20 -9548.0 -8494.0
TOMM22 -7224.0 -17231.0
TOMM40 -3248.0 -7299.0
TOMM5 -3807.0 -5370.0
TOMM6 -1003.0 -17024.0
TOMM7 -3730.0 -13840.0
TOMM70 -4078.0 -16306.0
VDAC1 -2358.0 -16357.0



REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
metric value
setSize 106
pMANOVA 2.77e-07
p.adjustMANOVA 1.82e-05
s.dist 0.314
s.Estill -0.0612
s.Novakovic -0.308
p.Estill 0.277
p.Novakovic 4.12e-08




Top 20 genes
Gene Estill Novakovic
RPL36 -15878 -16971
SPCS1 -14955 -17272
RPS5 -15070 -15693
SRPRA -14147 -16039
RPS21 -14247 -15846
SPCS3 -14774 -15170
RPL13 -13096 -17048
RPL8 -16023 -13701
RPLP2 -14824 -14743
RPL15 -13598 -15972
SRP9 -12584 -17181
SEC61G -12912 -16179
RPL35 -12031 -16424
RPL36AL -12581 -15545
RPS28 -12352 -15277
RPS15 -11816 -15841
RPL27A -11040 -16640
RPL7 -11616 -15741
RPS16 -12775 -13973
TRAM1 -12075 -14415

Click HERE to show all gene set members

All member genes
Estill Novakovic
DDOST -854.0 -14456.0
FAU -8361.0 -15762.0
RPL10A -4327.0 -16688.0
RPL10L -4672.0 1242.0
RPL11 -7730.0 -11362.0
RPL12 -1818.0 -7657.0
RPL13 -13096.0 -17048.0
RPL13A -1938.5 -10955.5
RPL14 -8334.0 -15519.0
RPL15 -13598.0 -15972.0
RPL17 -4720.0 -15113.0
RPL18 -6084.0 -16405.0
RPL18A -13854.0 -12314.0
RPL19 -9925.0 -950.0
RPL21 -9899.5 -13500.5
RPL22 -2661.0 -13474.0
RPL22L1 -2679.0 -16975.0
RPL23 -3278.0 -4599.0
RPL23A -8489.0 -13877.0
RPL24 813.0 329.0
RPL26 -7851.0 -14206.0
RPL26L1 -4159.0 -17223.0
RPL27 -10972.0 -14660.0
RPL27A -11040.0 -16640.0
RPL28 -7060.0 -12491.0
RPL29 -6766.0 -14551.0
RPL3 -4433.0 -6744.0
RPL30 -3473.0 -13276.0
RPL31 160.0 -9807.0
RPL32 -8290.0 -7245.0
RPL34 -3639.0 913.0
RPL35 -12031.0 -16424.0
RPL35A -563.0 -483.0
RPL36 -15878.0 -16971.0
RPL36AL -12581.0 -15545.0
RPL37 -5636.0 -11980.0
RPL37A -8914.0 -12749.0
RPL38 -3414.0 -3066.0
RPL39L -2329.0 -16531.0
RPL3L -13013.0 328.0
RPL4 -7696.0 199.0
RPL41 -8377.0 -15742.0
RPL5 1478.0 -13656.0
RPL6 718.0 -2953.0
RPL7 -11616.0 -15741.0
RPL7A -11184.0 -3709.0
RPL8 -16023.0 -13701.0
RPL9 -4066.0 -291.0
RPLP0 -7445.0 -14511.0
RPLP1 -5049.0 -3663.0
RPLP2 -14824.0 -14743.0
RPN1 -12573.0 -5768.0
RPN2 -7951.0 -10026.0
RPS10 -11363.0 -14602.0
RPS11 -12666.0 -8009.0
RPS12 -5554.0 -5380.0
RPS13 541.0 -12870.0
RPS14 -14985.0 -576.0
RPS15 -11816.0 -15841.0
RPS15A 1563.0 -10896.0
RPS16 -12775.0 -13973.0
RPS17 363.0 -17286.0
RPS18 -5492.0 -6509.0
RPS19 -4848.0 -463.0
RPS2 -8403.0 -13161.0
RPS20 -9963.0 -9064.0
RPS21 -14247.0 -15846.0
RPS23 -4455.0 -10331.0
RPS24 1255.0 -3232.0
RPS25 -2544.0 -11699.0
RPS26 802.0 -7841.0
RPS27 1722.0 -11381.0
RPS27A -11481.0 -2147.0
RPS27L -9482.0 -16569.0
RPS28 -12352.0 -15277.0
RPS29 -8298.0 -16523.0
RPS3 1404.0 -10369.0
RPS3A -10279.0 -15494.0
RPS5 -15070.0 -15693.0
RPS6 -16407.0 -6799.0
RPS7 -3124.0 -12481.0
RPS8 -9073.0 -1281.0
RPS9 -11982.0 -623.0
RPSA -4693.0 -3295.0
SEC11A -1941.0 -6232.0
SEC11C -9696.0 -11047.0
SEC61A1 -10621.0 -9787.0
SEC61A2 -11293.0 -10614.0
SEC61B -5808.5 -12331.0
SEC61G -12912.0 -16179.0
SPCS1 -14955.0 -17272.0
SPCS2 -7032.0 -14568.0
SPCS3 -14774.0 -15170.0
SRP14 -7444.0 -15842.0
SRP19 -907.0 -9199.0
SRP54 -6504.0 -7726.0
SRP68 -4242.0 -7502.0
SRP72 -10208.0 -14962.0
SRP9 -12584.0 -17181.0
SRPRA -14147.0 -16039.0
SRPRB -5891.0 -15710.0
SSR1 -4792.0 -8523.0
SSR2 -8494.0 -7855.0
SSR3 -9411.0 -4431.0
TRAM1 -12075.0 -14415.0
UBA52 -10894.0 -4996.0



REACTOME_EUKARYOTIC_TRANSLATION_INITIATION

REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
metric value
setSize 112
pMANOVA 3.23e-07
p.adjustMANOVA 2.04e-05
s.dist 0.29
s.Estill -0.00246
s.Novakovic -0.29
p.Estill 0.964
p.Novakovic 1.19e-07




Top 20 genes
Gene Estill Novakovic
RPL36 -15878 -16971
RPS5 -15070 -15693
EIF5B -13626 -16623
RPS21 -14247 -15846
EIF4EBP1 -13621 -16412
RPL13 -13096 -17048
RPL8 -16023 -13701
RPLP2 -14824 -14743
RPL15 -13598 -15972
EIF2B1 -12481 -16725
EIF3K -13263 -15469
EIF3M -14583 -13861
RPL35 -12031 -16424
RPL36AL -12581 -15545
RPS28 -12352 -15277
EIF2B2 -14471 -12953
RPS15 -11816 -15841
EIF2B4 -11102 -16666
RPL27A -11040 -16640
RPL7 -11616 -15741

Click HERE to show all gene set members

All member genes
Estill Novakovic
EIF2B1 -12481.0 -16725.0
EIF2B2 -14471.0 -12953.0
EIF2B3 -831.0 -8989.0
EIF2B4 -11102.0 -16666.0
EIF2B5 -11847.0 -6146.0
EIF2S1 -1610.0 -12288.0
EIF2S2 -9285.0 -8900.0
EIF3A -9723.0 -7339.0
EIF3B -3646.0 -3048.0
EIF3C 2672.5 -6604.0
EIF3D -9854.0 -12849.0
EIF3E 574.0 -9592.0
EIF3F -448.0 -5545.0
EIF3G -4857.0 -9751.0
EIF3H -5914.0 -7681.0
EIF3I -235.0 -12308.0
EIF3J -3349.0 -16580.0
EIF3K -13263.0 -15469.0
EIF3L -161.0 -14670.0
EIF3M -14583.0 -13861.0
EIF4A1 -4154.0 -1889.0
EIF4A2 -10801.0 -7915.0
EIF4B 1032.0 -5826.0
EIF4E -5903.0 -11598.0
EIF4EBP1 -13621.0 -16412.0
EIF4G1 -1656.0 -6170.0
EIF4H -8020.0 -13218.0
EIF5 -1328.0 -15948.0
EIF5B -13626.0 -16623.0
FAU -8361.0 -15762.0
PABPC1 -6557.0 -12965.0
RPL10A -4327.0 -16688.0
RPL10L -4672.0 1242.0
RPL11 -7730.0 -11362.0
RPL12 -1818.0 -7657.0
RPL13 -13096.0 -17048.0
RPL13A -1938.5 -10955.5
RPL14 -8334.0 -15519.0
RPL15 -13598.0 -15972.0
RPL17 -4720.0 -15113.0
RPL18 -6084.0 -16405.0
RPL18A -13854.0 -12314.0
RPL19 -9925.0 -950.0
RPL21 -9899.5 -13500.5
RPL22 -2661.0 -13474.0
RPL22L1 -2679.0 -16975.0
RPL23 -3278.0 -4599.0
RPL23A -8489.0 -13877.0
RPL24 813.0 329.0
RPL26 -7851.0 -14206.0
RPL26L1 -4159.0 -17223.0
RPL27 -10972.0 -14660.0
RPL27A -11040.0 -16640.0
RPL28 -7060.0 -12491.0
RPL29 -6766.0 -14551.0
RPL3 -4433.0 -6744.0
RPL30 -3473.0 -13276.0
RPL31 160.0 -9807.0
RPL32 -8290.0 -7245.0
RPL34 -3639.0 913.0
RPL35 -12031.0 -16424.0
RPL35A -563.0 -483.0
RPL36 -15878.0 -16971.0
RPL36AL -12581.0 -15545.0
RPL37 -5636.0 -11980.0
RPL37A -8914.0 -12749.0
RPL38 -3414.0 -3066.0
RPL39L -2329.0 -16531.0
RPL3L -13013.0 328.0
RPL4 -7696.0 199.0
RPL41 -8377.0 -15742.0
RPL5 1478.0 -13656.0
RPL6 718.0 -2953.0
RPL7 -11616.0 -15741.0
RPL7A -11184.0 -3709.0
RPL8 -16023.0 -13701.0
RPL9 -4066.0 -291.0
RPLP0 -7445.0 -14511.0
RPLP1 -5049.0 -3663.0
RPLP2 -14824.0 -14743.0
RPS10 -11363.0 -14602.0
RPS11 -12666.0 -8009.0
RPS12 -5554.0 -5380.0
RPS13 541.0 -12870.0
RPS14 -14985.0 -576.0
RPS15 -11816.0 -15841.0
RPS15A 1563.0 -10896.0
RPS16 -12775.0 -13973.0
RPS17 363.0 -17286.0
RPS18 -5492.0 -6509.0
RPS19 -4848.0 -463.0
RPS2 -8403.0 -13161.0
RPS20 -9963.0 -9064.0
RPS21 -14247.0 -15846.0
RPS23 -4455.0 -10331.0
RPS24 1255.0 -3232.0
RPS25 -2544.0 -11699.0
RPS26 802.0 -7841.0
RPS27 1722.0 -11381.0
RPS27A -11481.0 -2147.0
RPS27L -9482.0 -16569.0
RPS28 -12352.0 -15277.0
RPS29 -8298.0 -16523.0
RPS3 1404.0 -10369.0
RPS3A -10279.0 -15494.0
RPS5 -15070.0 -15693.0
RPS6 -16407.0 -6799.0
RPS7 -3124.0 -12481.0
RPS8 -9073.0 -1281.0
RPS9 -11982.0 -623.0
RPSA -4693.0 -3295.0
UBA52 -10894.0 -4996.0



REACTOME_HIV_LIFE_CYCLE

REACTOME_HIV_LIFE_CYCLE
metric value
setSize 145
pMANOVA 3.59e-07
p.adjustMANOVA 2.14e-05
s.dist 0.287
s.Estill -0.144
s.Novakovic -0.249
p.Estill 0.00277
p.Novakovic 2.37e-07




Top 20 genes
Gene Estill Novakovic
POLR2L -16149 -16420
NUP37 -15153 -17285
RANBP1 -15956 -16358
NUP153 -14779 -17257
HMGA1 -14283 -16529
CCNK -13936 -16492
TAF10 -15058 -15107
SUPT4H1 -12733 -17205
VPS37D -16162 -13504
TAF15 -15451 -13712
CHMP2B -13036 -15756
ELOA -12870 -15681
VTA1 -12630 -15941
RNMT -12479 -16072
TAF11 -12624 -15343
KPNA1 -15937 -12138
GTF2H3 -11360 -16525
NUP155 -12129 -15214
CHMP4C -11740 -15669
TPR -12390 -14677

Click HERE to show all gene set members

All member genes
Estill Novakovic
AAAS -5233.0 -3868
BANF1 -12198.0 -14222
CCNH -7680.0 -16219
CCNK -13936.0 -16492
CCNT1 -3658.0 -12061
CCNT2 -1647.0 -12723
CCR5 506.0 -10002
CD4 -1950.0 -3627
CDK7 -11455.0 -8357
CDK9 -3604.0 -16780
CHMP2A -6394.0 -196
CHMP2B -13036.0 -15756
CHMP3 -7699.0 8
CHMP4A -8786.0 -640
CHMP4B -15007.0 -3831
CHMP4C -11740.0 -15669
CHMP5 -8528.0 -14898
CHMP6 -13294.0 -8756
CHMP7 -3337.0 -3187
CTDP1 -410.0 -6290
CXCR4 -11164.0 -11871
ELL -7312.0 -5309
ELOA -12870.0 -15681
ELOA2 2395.0 71
ELOB -10647.0 -14069
ELOC -661.0 -10616
ERCC2 -6567.0 -8284
ERCC3 -5594.0 1083
FEN1 -3850.0 -9060
FURIN -10334.0 -10318
GTF2A1 -6836.0 -12317
GTF2A2 -1375.0 -14599
GTF2B 1347.0 530
GTF2E1 -3851.0 -5666
GTF2E2 -14763.0 -7061
GTF2F1 -4222.0 -13948
GTF2F2 -12677.0 -7911
GTF2H1 -6201.0 -14095
GTF2H3 -11360.0 -16525
GTF2H4 -2192.0 -10297
GTF2H5 -11128.0 -13219
HMGA1 -14283.0 -16529
KPNA1 -15937.0 -12138
LIG1 -15008.0 -2042
LIG4 -7548.0 -16753
MNAT1 -2305.0 547
MVB12A -12706.0 -9626
MVB12B -4905.0 -4177
NCBP1 -9559.5 -17039
NCBP2 -2050.0 -13946
NDC1 -11478.0 -8778
NEDD4L -1262.0 -6491
NELFA -11067.0 -10631
NELFB -4375.0 -5089
NELFCD -14735.0 -10484
NELFE -2132.0 -7082
NMT1 590.0 -3093
NMT2 -14307.0 -6409
NUP107 -7236.0 -8001
NUP133 -2470.0 -9143
NUP153 -14779.0 -17257
NUP155 -12129.0 -15214
NUP160 -11625.0 -12148
NUP188 -7877.0 -15187
NUP205 -7637.0 -436
NUP210 -10939.0 -191
NUP214 -13610.0 -5777
NUP35 -1428.0 -7296
NUP37 -15153.0 -17285
NUP42 -8725.0 -15797
NUP43 -6734.0 -13552
NUP50 -14109.0 -5828
NUP54 -12929.0 -7747
NUP58 -9205.0 -15350
NUP62 -3466.0 -2332
NUP85 -4129.0 -11356
NUP88 -7189.0 -10830
NUP93 -3140.0 -9015
NUP98 -8145.0 -10870
PDCD6IP -13542.0 -3859
POLR2A 281.0 -12598
POLR2B -6420.0 -12168
POLR2C -9988.0 -16056
POLR2D -5476.0 -17166
POLR2E -6353.0 -15885
POLR2F -11988.0 -11623
POLR2G 1063.0 -12103
POLR2H -12591.0 -11738
POLR2I -5956.0 -15772
POLR2J -11626.0 -4910
POLR2K -1330.0 590
POLR2L -16149.0 -16420
POM121 -13119.0 -11642
POM121C -3009.0 -6792
PPIA -10000.0 -12232
PSIP1 -4072.0 -16456
RAE1 -10699.0 -7730
RAN -10662.0 -16269
RANBP1 -15956.0 -16358
RANBP2 -8430.0 -15721
RANGAP1 -7181.0 -12265
RCC1 -308.0 -2368
RNGTT -13776.0 -3113
RNMT -12479.0 -16072
RPS27A -11481.0 -2147
SEC13 -8604.0 -10471
SEH1L -8901.0 -14935
SSRP1 -5354.0 -4346
SUPT16H -9317.0 -5433
SUPT4H1 -12733.0 -17205
SUPT5H -12113.0 -11711
TAF10 -15058.0 -15107
TAF11 -12624.0 -15343
TAF12 -9871.0 -9618
TAF13 -5566.0 -3630
TAF15 -15451.0 -13712
TAF1L -13645.0 -6482
TAF2 1567.0 -7361
TAF3 -8504.0 -10415
TAF4 -9100.0 -5425
TAF4B -1458.0 -1847
TAF5 -2237.0 -12426
TAF6 -2476.0 -11602
TAF7 -7257.0 -13845
TAF9 -9131.5 -16205
TBP -10253.0 -16301
TCEA1 -8621.0 -12734
TPR -12390.0 -14677
TSG101 308.0 -11208
UBA52 -10894.0 -4996
UBAP1 -4687.0 -12109
UBB -12784.0 -8060
UBC -11566.0 -692
VPS28 -15383.0 -4833
VPS37A -13712.0 -12137
VPS37B -10905.0 -9174
VPS37C -12485.0 -9996
VPS37D -16162.0 -13504
VPS4A -6364.0 -13269
VPS4B -6676.0 -16810
VTA1 -12630.0 -15941
XPO1 -11418.0 -13329
XRCC4 -5589.0 -14690
XRCC5 -1367.0 -12638
XRCC6 -10935.0 -3062



REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53
metric value
setSize 351
pMANOVA 3.71e-07
p.adjustMANOVA 2.14e-05
s.dist 0.188
s.Estill -0.113
s.Novakovic -0.151
p.Estill 0.000284
p.Novakovic 1.24e-06




Top 20 genes
Gene Estill Novakovic
PRDX5 -15848 -17210
E2F1 -16127 -16773
LAMTOR2 -15827 -16936
POLR2L -16149 -16420
PIN1 -15899 -16296
PRELID1 -16091 -15551
ATRIP -16346 -15271
CCNE1 -14226 -16873
PPP2CA -16303 -14663
PCNA -15776 -14982
COX14 -15402 -15339
DDIT4 -14788 -15720
TOPBP1 -14077 -16364
CCNK -13936 -16492
ING2 -15542 -14717
TAF10 -15058 -15107
NBN -14657 -15359
PLK2 -13084 -17131
GADD45A -15305 -14391
SUPT4H1 -12733 -17205

Click HERE to show all gene set members

All member genes
Estill Novakovic
AGO1 -747.0 -11588
AGO2 -1851.0 -1680
AGO3 -13810.0 -14109
AGO4 -10031.0 -8287
AIFM2 -1434.0 -6809
AKT1 -6145.0 -2432
AKT2 -12142.0 -6370
AKT3 -835.0 -5588
APAF1 -11661.0 -14718
ARID3A -2841.0 -2860
ATF2 -6207.0 -6194
ATM -10666.0 -3054
ATR -5921.0 -15232
ATRIP -16346.0 -15271
AURKA -8302.0 -8099
AURKB -585.0 -2715
BANP 15.0 -1286
BARD1 -9780.0 -7224
BAX -8736.0 -14875
BBC3 -14007.0 -15395
BCL2L14 1501.0 -4849
BCL6 -6524.0 -6685
BID -887.0 -9305
BIRC5 -509.0 -2514
BLM -8164.0 -12810
BNIP3L -4008.0 -14550
BRCA1 2021.0 628
BRD1 -3133.0 520
BRD7 -14496.0 -2366
BRIP1 1640.0 -14117
BRPF1 -6074.0 -14826
BRPF3 -13944.0 -14464
BTG2 -8814.0 -15838
CARM1 -7610.0 -7767
CASP1 -2020.0 -1042
CASP10 -14260.0 27
CASP2 -5396.0 -5277
CASP6 -3593.0 -6777
CCNA1 -11907.0 -12984
CCNA2 -6087.0 -16501
CCNB1 -15812.0 -8791
CCNE1 -14226.0 -16873
CCNE2 -10192.0 -8331
CCNG1 -5260.0 -15794
CCNH -7680.0 -16219
CCNK -13936.0 -16492
CCNT1 -3658.0 -12061
CCNT2 -1647.0 -12723
CDC25C -5672.0 -11011
CDK1 -629.5 -12551
CDK12 -524.0 -9290
CDK13 -10950.0 -10761
CDK2 -241.0 -10000
CDK5 -4592.0 -13544
CDK5R1 -8850.0 -15041
CDK7 -11455.0 -8357
CDK9 -3604.0 -16780
CDKN1A -7625.0 -12022
CDKN1B -15950.0 -12998
CDKN2A -13143.0 -1475
CENPJ -3229.0 -6985
CHD3 -3938.0 -1979
CHD4 -7292.0 -147
CHEK1 -5590.0 -8025
CHEK2 -2471.0 -14997
CNOT1 -2675.0 -11079
CNOT10 -6752.0 -9350
CNOT11 -15385.0 -5798
CNOT2 -10339.0 -8189
CNOT3 -9810.0 -11936
CNOT4 -2717.0 -13848
CNOT6 -7806.0 -3349
CNOT6L -15106.0 -13797
CNOT7 -15517.0 -12237
CNOT8 -6864.0 -11786
CNOT9 -5316.0 -4616
COX11 -10902.0 -15866
COX14 -15402.0 -15339
COX16 -10443.0 134
COX18 -14154.0 -9252
COX19 -8594.0 -5715
COX20 -9445.0 -15182
COX4I1 -8427.0 -17276
COX5A -12320.0 -13007
COX5B -14297.0 -12160
COX6A1 -2855.0 -15071
COX6B1 -4301.0 -9406
COX6C -6273.0 -2535
COX7A2L -12857.0 -12460
COX7C -11305.0 -12041
COX8A 1645.0 -16534
CRADD 1102.0 -3697
CREBBP 522.0 -5671
CSNK2A1 -10932.0 -4915
CSNK2A2 -15748.0 -7535
CSNK2B -367.0 -14595
CTDP1 -410.0 -6290
CYCS -13068.0 -11301
DAXX -5751.0 -1962
DDB2 -3131.0 -10737
DDIT4 -14788.0 -15720
DNA2 -3490.0 -12624
DYRK2 1332.0 -2076
E2F1 -16127.0 -16773
E2F4 -12111.0 -13562
E2F7 -7635.0 -11226
E2F8 -9471.0 -15301
EHMT1 708.0 -1487
EHMT2 -2283.0 -2489
ELL -7312.0 -5309
ELOA -12870.0 -15681
ELOA2 2395.0 71
ELOB -10647.0 -14069
ELOC -661.0 -10616
EP300 -1567.0 -10732
ERCC2 -6567.0 -8284
ERCC3 -5594.0 1083
EXO1 -10822.0 -13991
FANCC -2517.0 -6822
FANCD2 -11197.0 -6831
FANCI -6292.0 -15584
FAS -10156.0 -3617
FOS -6751.0 -11648
GADD45A -15305.0 -14391
GATAD2A -9795.0 -3375
GATAD2B -8455.0 -443
GLS -6798.0 -5184
GLS2 -9647.0 -1134
GPI -4859.0 -15098
GPX2 848.0 -12900
GSR 362.0 -15617
GTF2F1 -4222.0 -13948
GTF2F2 -12677.0 -7911
GTF2H1 -6201.0 -14095
GTF2H3 -11360.0 -16525
GTF2H4 -2192.0 -10297
GTF2H5 -11128.0 -13219
HDAC1 -9758.0 -7989
HDAC2 -13055.0 -10473
HIPK1 -8670.0 -910
HIPK2 -1479.0 -2831
HUS1 -1463.0 -13599
IGFBP3 -9231.0 -7195
ING2 -15542.0 -14717
ING5 -3048.0 -5274
JMY -12186.0 -15223
JUN -12813.0 -12417
KAT5 -7750.0 -6812
KAT6A -304.0 -8632
KMT5A -9451.0 -10739
L3MBTL1 -15421.0 -2863
LAMTOR1 -4373.0 -1485
LAMTOR2 -15827.0 -16936
LAMTOR3 -9742.0 -9546
LAMTOR4 -3862.0 -10879
LAMTOR5 -5629.0 -15481
LRPPRC 1909.0 -6137
MAP2K6 -1705.0 -7317
MAPK11 -5152.0 -7765
MAPK14 -13326.0 -12144
MAPKAP1 1196.0 -6058
MAPKAPK5 -15076.0 -14461
MBD3 -13231.0 -466
MDC1 -2592.0 -10245
MDM2 -10651.0 113
MDM4 -1979.0 -12057
MEAF6 -14719.0 -14680
MLH1 -8071.0 -12183
MLST8 -15381.0 -13231
MNAT1 -2305.0 547
MOV10 -9064.0 -10123
MRE11 -5819.0 -3826
MSH2 -13421.0 -10832
MTA2 -5187.0 -10678
MTOR 819.0 -8409
NBN -14657.0 -15359
NDRG1 -3540.0 -6124
NDUFA4 -7632.0 -13255
NELFA -11067.0 -10631
NELFB -4375.0 -5089
NELFCD -14735.0 -10484
NELFE -2132.0 -7082
NLRC4 -2291.0 -256
NOC2L -11252.0 -4926
NPM1 -8015.0 460
NUAK1 -3486.0 -12254
PCBP4 -14298.0 -11847
PCNA -15776.0 -14982
PDPK1 -6969.0 -8497
PERP -5431.0 -16142
PHF20 -8066.0 -3022
PIDD1 -5178.0 -5325
PIN1 -15899.0 -16296
PIP4K2A -2260.0 -1241
PIP4K2B -8123.0 -4136
PIP4K2C -12156.0 -11325
PIP4P1 -15741.0 -12910
PLAGL1 -8730.0 -4275
PLK2 -13084.0 -17131
PLK3 -16169.0 -8048
PMAIP1 -13933.0 -5793
PML 884.0 -927
PMS2 -11439.0 -13868
POLR2A 281.0 -12598
POLR2B -6420.0 -12168
POLR2C -9988.0 -16056
POLR2D -5476.0 -17166
POLR2E -6353.0 -15885
POLR2F -11988.0 -11623
POLR2G 1063.0 -12103
POLR2H -12591.0 -11738
POLR2I -5956.0 -15772
POLR2J -11626.0 -4910
POLR2K -1330.0 590
POLR2L -16149.0 -16420
POU4F1 -14828.0 -10820
POU4F2 -15824.0 -11982
PPP1R13B -10513.0 -10600
PPP1R13L -6913.0 -8480
PPP2CA -16303.0 -14663
PPP2CB -790.0 302
PPP2R1A -5112.0 -15337
PPP2R1B -6245.0 -9456
PPP2R5C -2004.0 -7658
PRDM1 -7231.0 -7600
PRDX1 -6218.0 336
PRDX2 -14231.0 -13787
PRDX5 -15848.0 -17210
PRELID1 -16091.0 -15551
PRELID3A -13943.0 -14239
PRKAA1 -12407.0 -14113
PRKAA2 -11474.0 -7757
PRKAB1 -5355.0 -10292
PRKAB2 -5410.0 -17108
PRKAG1 -11911.0 -13732
PRKAG2 -3631.0 -1357
PRKAG3 -15909.0 -921
PRMT1 -3021.0 -8191
PRMT5 -4800.0 -629
PRR5 -14722.0 -5609
PTEN -14678.0 -7735
RABGGTA -9683.0 -12255
RABGGTB -5319.0 -3999
RAD1 -10349.0 -12579
RAD17 -9131.5 -14142
RAD50 -5291.0 -7668
RAD51D -15461.0 -3733
RAD9A -13056.0 -11198
RAD9B -14660.0 -6250
RBBP4 -9690.0 -15408
RBBP8 -12465.0 -15065
RBL1 823.0 -5072
RBL2 -7303.0 -11548
RFC2 -11390.0 -13410
RFC3 1547.0 -8638
RFC4 -12661.0 -13699
RFC5 -3459.0 -7830
RFFL -3531.0 -2935
RGCC -3760.0 -3951
RHEB -4914.0 -7995
RHNO1 -10225.0 -9607
RICTOR -10018.0 -14893
RMI1 -14153.0 -11854
RMI2 -8312.0 -8455
RNF34 -10150.0 -10107
RPA1 1482.0 -2054
RPA2 -6976.0 -8172
RPA3 -13260.0 -8291
RPS27A -11481.0 -2147
RPTOR -686.0 -708
RRAGA -1430.0 -17105
RRAGC -5607.0 -14388
RRAGD -7560.0 -10498
RRM2B -12861.0 -2894
SCO1 -13917.0 -15055
SCO2 -15098.0 -13166
SESN1 -14137.0 -12007
SESN2 -7923.0 -16070
SESN3 -12938.0 -3165
SETD9 -9708.0 -10866
SFN -14353.0 255
SGK1 -5640.0 -5353
SLC38A9 -11447.0 -16016
SMYD2 -1689.0 -12804
SSRP1 -5354.0 -4346
STEAP3 -8124.0 -2475
STK11 -6603.0 -9371
SUPT16H -9317.0 -5433
SUPT4H1 -12733.0 -17205
SUPT5H -12113.0 -11711
SURF1 -15514.0 -12618
TACO1 -1219.0 -3712
TAF10 -15058.0 -15107
TAF11 -12624.0 -15343
TAF12 -9871.0 -9618
TAF13 -5566.0 -3630
TAF15 -15451.0 -13712
TAF1L -13645.0 -6482
TAF2 1567.0 -7361
TAF3 -8504.0 -10415
TAF4 -9100.0 -5425
TAF4B -1458.0 -1847
TAF5 -2237.0 -12426
TAF6 -2476.0 -11602
TAF7 -7257.0 -13845
TAF9 -9131.5 -16205
TBP -10253.0 -16301
TCEA1 -8621.0 -12734
TFDP1 -507.0 -45
TFDP2 -14013.0 -2679
TIGAR -9356.0 -4639
TMEM219 -4485.0 -1600
TNFRSF10A -2009.0 -12704
TNFRSF10B -10062.0 1321
TNFRSF10C -12006.0 -9166
TNFRSF10D -5365.0 -4909
TNKS1BP1 -5616.0 -3233
TNRC6A -9124.0 -9298
TNRC6B -6203.0 -2867
TNRC6C 404.0 -4745
TOP3A -7766.0 -4898
TOPBP1 -14077.0 -16364
TP53 -3878.0 -8153
TP53AIP1 -1054.0 -3042
TP53BP2 -11762.0 -9914
TP53I3 -4173.0 -12907
TP53INP1 -3470.0 -7805
TP53RK -8877.0 -5629
TP63 -8903.0 -9867
TP73 -14277.0 -12325
TPX2 -11984.0 308
TRIAP1 -7999.0 -17217
TSC1 829.0 -13931
TSC2 -8453.0 -3378
TTC5 -3418.0 -2975
TXN -7710.0 -11678
TXNRD1 -6140.0 -5110
UBA52 -10894.0 -4996
UBB -12784.0 -8060
UBC -11566.0 -692
USP2 -12462.0 -11680
USP7 -6902.0 -2397
WRN -10141.5 -6355
YWHAB -12447.0 -2244
YWHAE -7622.0 -13250
YWHAG -5540.0 -4226
YWHAH -15299.0 -11577
YWHAQ -14845.0 -8678
YWHAZ -11791.0 -10782
ZNF385A -10615.0 -5596
ZNF420 -14248.0 -2308



REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL

REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL
metric value
setSize 121
pMANOVA 3.77e-07
p.adjustMANOVA 2.14e-05
s.dist 0.313
s.Estill 0.153
s.Novakovic 0.273
p.Estill 0.00376
p.Novakovic 2.08e-07




Top 20 genes
Gene Estill Novakovic
SIGLEC11 1950 1780
FCGR2B 2242 1488
FCGR1A 2487 253
LILRB4 1697 309
CD1C 2321 177
CD1A 2463 125
JAML 1189 76
CD300LD 79 991

Click HERE to show all gene set members

All member genes
Estill Novakovic
B2M -9736 -1528
C3 -3487 -4048
CD160 -12842 -3914
CD19 -9773 867
CD1A 2463 125
CD1B 2387 -9145
CD1C 2321 177
CD1D -4304 -2190
CD200 -6309 -11604
CD200R1 1773 -2564
CD22 -701 -2552
CD226 2695 -11201
CD247 -4987 -4081
CD300A -14785 -12045
CD300C -4765 -3072
CD300E -8068 -4199
CD300LB -10223 583
CD300LD 79 991
CD300LF -720 -12339
CD300LG -5470 -5419
CD33 -1125 -5949
CD34 -12341 -6839
CD3D -3583 -16570
CD3E -633 -1054
CD3G -610 -13183
CD40 -5556 1431
CD81 -4221 -4228
CD8A -8908 -6401
CD8B -36 -6692
CD96 1503 -5113
CDH1 -2667 -6402
CLEC2D -5006 -2979
CLEC4G -1966 970
COL17A1 1218 -1360
COL1A1 -6605 -9851
COL1A2 -6107 -9390
COL2A1 -11166 -14153
COLEC12 -7881 -6199
CRTAM 586 -987
CXADR -12256 -7629
FCGR1A 2487 253
FCGR2B 2242 1488
FCGR3A -16251 1513
HCST -14664 -1765
HLA-A -11670 -15381
HLA-B -4883 -13938
HLA-C -7426 -16151
HLA-E -5169 -16076
HLA-F -2480 -12449
HLA-G -2729 -8695
ICAM1 -1758 -13769
ICAM2 -8316 193
ICAM3 -2032 -573
ICAM4 -7691 -13665
ICAM5 -6941 -14437
IFITM1 -7600 -16542
ITGA4 -15859 -12983
ITGAL -2798 712
ITGB1 -8035 -14961
ITGB2 -5999 -349
ITGB7 -4902 -3122
JAML 1189 76
KIR2DL1 -358 500
KIR2DL3 -977 1100
KIR2DL4 -8918 1379
KIR3DL1 -5790 1737
KIR3DL2 -801 1033
KLRB1 -16078 -7643
KLRC1 -9370 -15616
KLRD1 -1117 -6157
KLRK1 -3916 -4736
LAIR1 -9587 420
LAIR2 -1655 -2610
LILRA1 1739 -787
LILRA2 -7183 887
LILRA3 -6212 1456
LILRA4 -880 -3061
LILRA5 -1196 -5984
LILRA6 -6937 -5006
LILRB1 -4760 388
LILRB2 -7386 -4528
LILRB3 -12378 -4094
LILRB4 1697 309
LILRB5 -15995 -4541
MADCAM1 -15215 -15390
MICA -9054 61
MICB -5300 -215
NCR1 -15997 -12547
NCR2 1093 -2303
NCR3 -6110 -1599
NCR3LG1 -12022 -16888
NECTIN2 -15893 -12096
NPDC1 -12124 -3355
OSCAR -9829 -11929
PIANP -14122 -15305
PILRA -3978 -1056
PILRB -11192 -3032
PVR -5847 -5031
RAET1E -54 -1583
SELL -658 1207
SFTPD -1654 1423
SH2D1B 1480 -9652
SIGLEC1 -8362 -564
SIGLEC10 -1015 -2015
SIGLEC11 1950 1780
SIGLEC12 -2687 956
SIGLEC5 -1624 768
SIGLEC6 -8729 -10559
SIGLEC7 898 -123
SIGLEC8 -14267 1553
SIGLEC9 -13599 -5967
SLAMF7 1959 -4255
TREM1 -1674 -4003
TREM2 -1613 -1522
TREML1 -4613 -1012
TREML2 -12500 -10153
TREML4 2155 -10328
TYROBP -1106 -5232
ULBP1 -8127 -6003
ULBP3 -10219 -11708
VCAM1 -16410 -952



REACTOME_COMPLEMENT_CASCADE

REACTOME_COMPLEMENT_CASCADE
metric value
setSize 54
pMANOVA 4.49e-07
p.adjustMANOVA 2.46e-05
s.dist 0.467
s.Estill 0.236
s.Novakovic 0.402
p.Estill 0.0027
p.Novakovic 3.1e-07




Top 20 genes
Gene Estill Novakovic
C3AR1 1676 1588
CFHR1 2215 1070
CFH 2310 554
C4BPA 761 1383
F2 55 706

Click HERE to show all gene set members

All member genes
Estill Novakovic
C1QA -12605.0 -2120
C1QB -9080.0 -4785
C1QC -14699.0 -2124
C1R -1314.0 -3488
C1S 1017.0 -15
C2 -4298.0 -3478
C3 -3487.0 -4048
C3AR1 1676.0 1588
C4A -9092.5 1061
C4B -9092.5 1266
C4BPA 761.0 1383
C4BPB 1681.0 -4887
C5AR1 -12617.0 -3386
C5AR2 -3519.0 -3467
C6 690.0 -6944
C7 -13407.0 -8968
C8A -3515.0 -3258
C8B 2036.0 -8831
C8G -4841.0 -14864
C9 1311.0 -2703
CD19 -9773.0 867
CD46 -8389.0 -16448
CD55 -12576.0 -5644
CD59 -2659.0 -10327
CD81 -4221.0 -4228
CFB -13399.0 -358
CFD -11511.0 -2471
CFH 2310.0 554
CFHR1 2215.0 1070
CFHR2 -7959.0 1650
CFHR4 -3002.0 -2614
CFHR5 1695.0 -37
CFI 736.0 -4053
CLU -4915.0 -6709
COLEC10 1751.0 -5357
COLEC11 -7820.0 721
CPB2 -3578.0 -1220
CPN1 2195.0 -3354
CPN2 -2140.0 -719
CR1 -9172.0 -6776
CR2 -2503.0 -11412
CRP 2444.0 -13642
ELANE -6154.0 1156
F2 55.0 706
FCN1 -13256.0 930
FCN2 -9704.0 -7825
FCN3 -848.0 -688
GZMM -15169.0 -2992
MASP1 2282.0 -4508
MASP2 -1909.0 -2227
MBL2 1338.0 -7122
PROS1 -13923.0 -4088
SERPING1 416.0 -8796
VTN -10290.0 -8822



REACTOME_MITOCHONDRIAL_TRANSLATION

REACTOME_MITOCHONDRIAL_TRANSLATION
metric value
setSize 93
pMANOVA 7.14e-07
p.adjustMANOVA 3.78e-05
s.dist 0.325
s.Estill -0.0652
s.Novakovic -0.319
p.Estill 0.277
p.Novakovic 1.08e-07




Top 20 genes
Gene Estill Novakovic
MRPL17 -16116 -17121
MRPL40 -16338 -16665
AURKAIP1 -15638 -16852
MRPS26 -14964 -17073
MRPL42 -15800 -16106
MRPL55 -14809 -16520
MTIF3 -15953 -14799
MRPL57 -15821 -14549
MRPL38 -13455 -16751
MRPS34 -12970 -16982
CHCHD1 -12312 -17184
MRPL36 -13742 -14953
GFM2 -12136 -16596
MRPL19 -12430 -15859
MRPL44 -11032 -16378
MRPL12 -11895 -14993
MRPL41 -10344 -16980
MRPL34 -15620 -11069
MRPS25 -11286 -14377
MRPL32 -10183 -15657

Click HERE to show all gene set members

All member genes
Estill Novakovic
AURKAIP1 -15638 -16852
CHCHD1 -12312 -17184
DAP3 -4635 -238
ERAL1 782 -9714
GADD45GIP1 -9874 -1382
GFM1 -9555 -13224
GFM2 -12136 -16596
MRPL1 -2367 -4644
MRPL10 -7197 -12644
MRPL11 125 -1062
MRPL12 -11895 -14993
MRPL13 1660 -13367
MRPL14 -11843 -8304
MRPL15 -7349 -10727
MRPL16 -1917 894
MRPL17 -16116 -17121
MRPL18 -4819 -14508
MRPL19 -12430 -15859
MRPL2 -212 -705
MRPL20 -9523 -12591
MRPL21 -7755 -11862
MRPL22 -870 -11857
MRPL23 -11517 -10457
MRPL24 811 -13987
MRPL27 -7791 -10842
MRPL28 -12659 -5135
MRPL3 -6387 -13830
MRPL30 -7793 -11475
MRPL32 -10183 -15657
MRPL33 -10421 -4205
MRPL34 -15620 -11069
MRPL35 2189 -4760
MRPL36 -13742 -14953
MRPL37 -12016 -9872
MRPL38 -13455 -16751
MRPL39 -5542 -8518
MRPL4 -8036 -8427
MRPL40 -16338 -16665
MRPL41 -10344 -16980
MRPL42 -15800 -16106
MRPL43 -12670 -7226
MRPL44 -11032 -16378
MRPL45 833 102
MRPL46 -15794 -7820
MRPL47 -1153 -15015
MRPL48 786 -16397
MRPL49 -7465 -15622
MRPL50 -4013 -1457
MRPL51 -4931 -10319
MRPL52 -8844 -10845
MRPL53 -2699 -16266
MRPL54 -1078 -8366
MRPL55 -14809 -16520
MRPL57 -15821 -14549
MRPL58 -6773 -15593
MRPL9 -733 -6246
MRPS10 -5686 -6312
MRPS11 -16088 -9726
MRPS12 -4001 -14068
MRPS14 -1138 -9047
MRPS15 -2994 -16260
MRPS16 -7012 -13658
MRPS17 -5138 -7091
MRPS18A -1802 -6739
MRPS18B -3147 -8543
MRPS18C -11737 -2061
MRPS2 -2222 -14643
MRPS21 -9929 -2756
MRPS22 -3049 -8271
MRPS23 -8408 -15099
MRPS24 -9942 -12429
MRPS25 -11286 -14377
MRPS26 -14964 -17073
MRPS27 -4134 -11535
MRPS28 -8812 -8703
MRPS30 -251 -13585
MRPS31 -14696 -10357
MRPS33 -10752 -2795
MRPS34 -12970 -16982
MRPS35 -10186 -7152
MRPS5 -2094 -8961
MRPS6 -10130 -2730
MRPS7 552 -12911
MRPS9 -6686 -14761
MRRF -874 -11519
MTFMT -9209 -16939
MTIF2 -14408 -7565
MTIF3 -15953 -14799
MTRF1L -7918 -9437
OXA1L 1460 -16371
PTCD3 -5414 -10965
TSFM -471 -5035
TUFM -10548 -4900



REACTOME_TRNA_PROCESSING

REACTOME_TRNA_PROCESSING
metric value
setSize 105
pMANOVA 7.56e-07
p.adjustMANOVA 3.88e-05
s.dist 0.312
s.Estill -0.0872
s.Novakovic -0.3
p.Estill 0.123
p.Novakovic 1.12e-07




Top 20 genes
Gene Estill Novakovic
TRMT112 -15892 -17246
NUP37 -15153 -17285
NUP153 -14779 -17257
TSEN54 -16030 -15578
LCMT2 -16031 -13995
PUS3 -13563 -15952
TSEN34 -13266 -16061
CTU2 -14574 -13184
NUP155 -12129 -15214
TRMT1 -11729 -15557
TPR -12390 -14677
RAN -10662 -16269
QTRT2 -10039 -17079
TRNT1 -10818 -15627
ZBTB8OS -12713 -13083
PUS7 -10698 -15294
ELAC2 -14476 -11266
RPPH1 -15738 -10255
XPOT -9162 -16681
POM121 -13119 -11642

Click HERE to show all gene set members

All member genes
Estill Novakovic
AAAS -5233 -3868
ADAT1 -3714 -9673
ADAT2 -12708 -10546
ADAT3 -10691 -11921
ALKBH8 -1583 -3149
C2orf49 -13880 -6015
CDKAL1 -951 -6811
CLP1 -7232 -15909
CPSF1 -8024 -3809
CPSF4 -8835 -13204
CTU1 198 -9477
CTU2 -14574 -13184
DDX1 -7482 -12132
DUS2 -13968 -10900
ELAC2 -14476 -11266
EPRS1 -11941 -6090
FAM98B -4564 -12340
GTPBP3 -8194 -9328
LCMT2 -16031 -13995
METTL1 -3382 -11518
MTO1 -4341 -10140
NDC1 -11478 -8778
NSUN2 -3940 -10093
NSUN6 -4511 -4749
NUP107 -7236 -8001
NUP133 -2470 -9143
NUP153 -14779 -17257
NUP155 -12129 -15214
NUP160 -11625 -12148
NUP188 -7877 -15187
NUP205 -7637 -436
NUP210 -10939 -191
NUP214 -13610 -5777
NUP35 -1428 -7296
NUP37 -15153 -17285
NUP42 -8725 -15797
NUP43 -6734 -13552
NUP50 -14109 -5828
NUP54 -12929 -7747
NUP58 -9205 -15350
NUP62 -3466 -2332
NUP85 -4129 -11356
NUP88 -7189 -10830
NUP93 -3140 -9015
NUP98 -8145 -10870
OSGEP -9832 -14157
POM121 -13119 -11642
POM121C -3009 -6792
POP1 -6247 -16499
POP4 395 -5118
POP5 -3203 -10935
POP7 -5863 -13522
PRORP -2590 -11245
PUS1 -9047 -8402
PUS3 -13563 -15952
PUS7 -10698 -15294
QTRT1 -5850 -6579
QTRT2 -10039 -17079
RAE1 -10699 -7730
RAN -10662 -16269
RANBP2 -8430 -15721
RPP14 -8364 -10025
RPP21 -8006 -11507
RPP25 -3896 -16883
RPP30 -11196 -2239
RPP38 -5496 -16696
RPP40 -6839 -9297
RPPH1 -15738 -10255
RTCB -9353 -11164
RTRAF -3517 -8461
SEC13 -8604 -10471
SEH1L -8901 -14935
THADA -1337 -2908
THG1L 1188 -5042
TP53RK -8877 -5629
TPR -12390 -14677
TPRKB -46 -10383
TRDMT1 -5126 -15562
TRIT1 -9030 -15351
TRMT1 -11729 -15557
TRMT10A -4791 -3339
TRMT10C -5143 -14640
TRMT11 -2707 -10757
TRMT112 -15892 -17246
TRMT12 2267 1361
TRMT13 -2809 -10634
TRMT44 -654 -158
TRMT5 -1385 -14147
TRMT6 -5520 -9734
TRMT61A -1675 -2531
TRMT61B -10124 -13102
TRMT9B -12820 -9656
TRMU -8154 -15456
TRNT1 -10818 -15627
TSEN15 -14025 -3894
TSEN2 -6607 -10570
TSEN34 -13266 -16061
TSEN54 -16030 -15578
TYW1 -8652 -11070
TYW3 1154 -16528
TYW5 -7638 -15684
URM1 1159 -7404
WDR4 -11046 -6774
XPOT -9162 -16681
ZBTB8OS -12713 -13083



REACTOME_THE_CITRIC_ACID_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT

REACTOME_THE_CITRIC_ACID_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT
metric value
setSize 159
pMANOVA 7.84e-07
p.adjustMANOVA 3.9e-05
s.dist 0.264
s.Estill -0.115
s.Novakovic -0.237
p.Estill 0.012
p.Novakovic 2.5e-07




Top 20 genes
Gene Estill Novakovic
PDP1 -14800 -16472
ATP5ME -15364 -15648
NDUFA6 -14150 -16892
COX14 -15402 -15339
FAHD1 -15627 -14881
MPC1 -15242 -14492
NDUFV2 -13182 -16649
ETFA -13277 -16406
ATP5F1E -13241 -16442
SLC25A27 -14654 -14317
SCO1 -13917 -15055
DLST -14278 -14273
UCP1 -13081 -15392
CYC1 -14875 -13374
SCO2 -15098 -13166
FH -11749 -16778
SURF1 -15514 -12618
PDHB -14961 -13043
NDUFAF5 -15596 -12181
ETFDH -12171 -15530

Click HERE to show all gene set members

All member genes
Estill Novakovic
ACAD9 -10540.0 -11360.0
ACO2 -1344.0 -9099.0
ADHFE1 -8688.0 -8628.0
ATP5F1A -7194.0 -13341.0
ATP5F1B -10388.0 -12106.0
ATP5F1C -8576.0 -16028.0
ATP5F1D -12279.0 -13408.0
ATP5F1E -13241.0 -16442.0
ATP5MC1 -7648.0 -15300.0
ATP5MC2 -5377.0 -4017.0
ATP5MC3 -11250.0 -11912.0
ATP5ME -15364.0 -15648.0
ATP5MF -6874.0 -7164.0
ATP5MG -5879.0 -2148.0
ATP5PB -7065.0 -16718.0
ATP5PD -10606.0 -13471.0
ATP5PF -12879.0 -10986.0
ATP5PO -15532.0 -11092.0
BSG -4193.0 -9689.0
COA1 -6143.0 -9072.0
COQ10A -3932.0 -7027.0
COQ10B -16021.0 -8221.0
COX11 -10902.0 -15866.0
COX14 -15402.0 -15339.0
COX16 -10443.0 134.0
COX18 -14154.0 -9252.0
COX19 -8594.0 -5715.0
COX20 -9445.0 -15182.0
COX4I1 -8427.0 -17276.0
COX5A -12320.0 -13007.0
COX5B -14297.0 -12160.0
COX6A1 -2855.0 -15071.0
COX6B1 -4301.0 -9406.0
COX6C -6273.0 -2535.0
COX7A2L -12857.0 -12460.0
COX7C -11305.0 -12041.0
COX8A 1645.0 -16534.0
CS -1189.0 -1013.0
CYC1 -14875.0 -13374.0
CYCS -13068.0 -11301.0
D2HGDH -2085.0 -2618.0
DLAT -11732.0 -14219.0
DLD -15073.0 -11511.0
DLST -14278.0 -14273.0
DMAC2L -13430.5 -13979.0
ECSIT -5551.0 -14185.0
ETFA -13277.0 -16406.0
ETFB -4797.0 -7538.0
ETFDH -12171.0 -15530.0
FAHD1 -15627.0 -14881.0
FH -11749.0 -16778.0
GLO1 -6858.0 -10647.0
GSTZ1 -11406.0 -15454.0
HAGH -12415.0 -12099.0
IDH2 -14690.0 -4485.0
IDH3A -15248.0 -5234.0
IDH3B -5445.0 -11215.0
L2HGDH -13430.5 -11905.0
LDHA -15273.0 -11705.0
LDHAL6A 2550.0 1660.0
LDHAL6B 2046.0 537.0
LDHB -15430.0 -5889.0
LDHC 2406.0 1632.0
LRPPRC 1909.0 -6137.0
MDH2 -5044.0 -8944.0
ME1 -1863.0 -14750.0
ME2 -11564.0 -8740.0
ME3 -2619.0 -10308.0
MPC1 -15242.0 -14492.0
MPC2 -12958.0 -13908.0
NDUFA10 -7174.0 -14744.0
NDUFA11 -5001.0 -8180.0
NDUFA12 -3151.0 -13242.0
NDUFA13 -12987.0 -5608.0
NDUFA2 -1203.0 -680.0
NDUFA3 -12400.0 -14967.0
NDUFA4 -7632.0 -13255.0
NDUFA5 1936.0 -2847.0
NDUFA6 -14150.0 -16892.0
NDUFA7 -10191.0 -11310.0
NDUFA8 -8329.5 -4531.0
NDUFA9 -8325.0 -14355.0
NDUFAB1 -7899.0 -5537.0
NDUFAF1 -1578.0 -4840.0
NDUFAF2 -4843.0 -2830.0
NDUFAF3 -2795.0 -15109.0
NDUFAF4 -10078.0 -12078.0
NDUFAF5 -15596.0 -12181.0
NDUFAF6 -5395.0 -3518.0
NDUFAF7 -8108.0 -14716.0
NDUFB1 -7712.0 -15971.0
NDUFB10 -12869.0 -12218.0
NDUFB2 -13672.0 -6873.0
NDUFB3 -567.0 -13200.0
NDUFB4 -10415.0 -12831.0
NDUFB5 -956.0 -15790.0
NDUFB6 985.0 -527.0
NDUFB7 -8437.0 -12378.0
NDUFB8 -1760.0 -10491.0
NDUFB9 -7078.0 -6396.0
NDUFC1 -11387.0 -8669.0
NDUFC2 -4484.0 -13141.0
NDUFS1 -6870.0 -16459.0
NDUFS2 -10178.0 -1790.0
NDUFS3 -3424.0 -16573.0
NDUFS4 -151.0 -4779.0
NDUFS5 -793.0 -25.0
NDUFS6 -3812.0 -8278.0
NDUFS7 -7919.0 -12307.0
NDUFS8 -9380.0 -8911.0
NDUFV1 -6847.0 -13078.0
NDUFV2 -13182.0 -16649.0
NDUFV3 -6044.0 -14913.0
NNT -9537.0 -1653.0
NUBPL -4480.0 -3541.0
OGDH -13955.0 -707.0
PDHA2 772.0 1231.0
PDHB -14961.0 -13043.0
PDHX -15842.0 -10437.0
PDK1 -7684.0 -8202.0
PDK2 -11214.0 -14582.0
PDK4 -12296.0 -14520.0
PDP1 -14800.0 -16472.0
PDP2 -8193.0 -8414.0
PDPR -531.0 -288.0
PM20D1 1975.0 96.0
PPARD -12064.0 -4881.0
RXRA -6530.0 -1218.0
SCO1 -13917.0 -15055.0
SCO2 -15098.0 -13166.0
SDHA -2270.0 -534.0
SDHB 805.0 -13726.0
SDHC -7568.0 -16770.0
SDHD -9247.5 -11433.5
SLC16A1 -7753.0 -6884.0
SLC16A3 -14164.0 -2139.0
SLC16A8 -11303.0 -1046.0
SLC25A27 -14654.0 -14317.0
SUCLA2 -4507.0 -7728.0
SUCLG1 1175.0 -5880.0
SUCLG2 -1798.0 -11472.0
SURF1 -15514.0 -12618.0
TACO1 -1219.0 -3712.0
TIMMDC1 -7103.0 -7457.0
TMEM126B -4224.0 -13249.0
TMEM186 -7550.0 -16914.0
TRAP1 -2727.0 -8701.0
UCP1 -13081.0 -15392.0
UCP2 -9494.0 -12337.0
UCP3 -3453.0 -1330.0
UQCR10 -7069.0 -17114.0
UQCR11 -4968.0 -6613.0
UQCRB -5109.0 -9427.0
UQCRC1 -1297.0 -5101.0
UQCRC2 -9513.0 -5738.0
UQCRFS1 -9449.0 -13526.0
UQCRH -4053.0 -9223.0
UQCRQ -486.0 -12784.0
VDAC1 -2358.0 -16357.0



REACTOME_SIGNALING_BY_ROBO_RECEPTORS

REACTOME_SIGNALING_BY_ROBO_RECEPTORS
metric value
setSize 207
pMANOVA 2.93e-06
p.adjustMANOVA 0.000142
s.dist 0.202
s.Estill -0.0191
s.Novakovic -0.201
p.Estill 0.635
p.Novakovic 6.39e-07




Top 20 genes
Gene Estill Novakovic
RPL36 -15878 -16971
ISL1 -15375 -16438
PFN2 -16200 -15472
PSMA7 -15238 -16097
PSMD1 -15755 -15264
RPS5 -15070 -15693
RPS21 -14247 -15846
AKAP5 -15560 -14487
SOS2 -13566 -16495
RPL13 -13096 -17048
MSI1 -13050 -16836
RPL8 -16023 -13701
RPLP2 -14824 -14743
RPL15 -13598 -15972
PSMB2 -15087 -14324
PRKAR2A -13547 -14987
RPL35 -12031 -16424
PPP3CB -15374 -12751
RPL36AL -12581 -15545
PFN1 -14906 -12817

Click HERE to show all gene set members

All member genes
Estill Novakovic
ABL1 -712.0 -2410.0
ABL2 -11656.0 -4721.0
AKAP5 -15560.0 -14487.0
ARHGAP39 -7374.0 -1100.0
CAP1 -328.0 -9288.0
CAP2 -9976.0 -1740.0
CASC3 -11669.0 -3656.0
CDC42 -1305.0 -2530.0
CLASP1 -368.0 -10453.0
CLASP2 -14327.0 -9568.0
CUL2 -3906.0 -4879.0
CXCL12 -6390.0 -14326.0
CXCR4 -11164.0 -11871.0
DAG1 -2225.0 -7816.0
DCC -11161.0 -960.0
EIF4A3 -30.0 -4961.0
EIF4G1 -1656.0 -6170.0
ELOB -10647.0 -14069.0
ELOC -661.0 -10616.0
ENAH -11849.0 -7265.0
ETF1 -9521.0 -10565.0
EVL -8900.0 -913.0
FAU -8361.0 -15762.0
FLRT3 2596.0 -4343.0
GPC1 -11109.0 -7559.0
GSPT1 -12163.0 -2538.0
HOXA2 1661.0 -8934.0
ISL1 -15375.0 -16438.0
LDB1 -7790.0 -15978.0
LHX2 -4692.0 -4844.0
LHX3 -5032.0 -14031.0
LHX4 -7545.0 -5614.0
LHX9 -12221.0 -12430.0
MAGOH -2775.0 -16629.0
MAGOHB -7797.0 -17140.0
MSI1 -13050.0 -16836.0
MYO9B -3582.0 -2636.0
NCBP1 -9559.5 -17039.0
NCBP2 -2050.0 -13946.0
NCK1 -13196.0 -4569.0
NCK2 131.0 -2249.0
NELL2 -5483.0 -10284.0
NRP1 1486.0 -7792.0
NTN1 -7687.0 -4395.0
PABPC1 -6557.0 -12965.0
PAK1 -8178.0 -7213.0
PAK2 -1043.0 -795.0
PAK4 -12568.0 -8814.0
PAK5 -11512.0 -14648.0
PAK6 -11444.0 -8558.0
PFN1 -14906.0 -12817.0
PFN2 -16200.0 -15472.0
PPP3CB -15374.0 -12751.0
PRKACA -15621.0 -10373.0
PRKACB -6996.0 -8892.0
PRKACG -11377.0 -8915.0
PRKAR2A -13547.0 -14987.0
PRKCA -1.0 -3348.0
PSMA1 -8781.0 -2177.0
PSMA2 -7391.0 -13190.0
PSMA3 -543.0 -12585.0
PSMA4 -1489.0 -11130.0
PSMA5 -5612.0 -12086.0
PSMA6 -5453.0 -7068.0
PSMA7 -15238.0 -16097.0
PSMA8 -12998.0 1341.0
PSMB1 -7998.0 -12452.0
PSMB10 1546.0 -12645.0
PSMB11 -7675.0 461.0
PSMB2 -15087.0 -14324.0
PSMB3 -2943.0 -16574.0
PSMB4 -3092.0 -17193.0
PSMB5 -2173.0 -13304.0
PSMB6 -1270.0 -15778.0
PSMB7 1688.0 1166.0
PSMB8 251.0 -10098.0
PSMB9 -4477.0 -14712.0
PSMC1 -2414.0 -13145.0
PSMC2 -315.0 -2310.0
PSMC3 -7461.0 -17123.0
PSMC4 459.0 -4407.0
PSMC5 -9725.0 -12293.0
PSMC6 -7301.0 332.0
PSMD1 -15755.0 -15264.0
PSMD11 -6796.0 -15996.0
PSMD12 -13229.0 -1837.0
PSMD13 -9340.0 -12191.0
PSMD14 -9752.0 -14404.0
PSMD2 -5101.0 -4469.0
PSMD3 -6030.0 -12489.0
PSMD4 -6049.0 -14518.0
PSMD5 2564.0 -8724.0
PSMD6 -5979.0 -12939.0
PSMD7 -12233.0 -5710.0
PSMD8 -9781.0 -13888.0
PSMD9 -11408.0 -10645.0
PSME1 -9760.0 -16962.0
PSME2 67.0 -15711.0
PSME3 -4965.0 -13719.0
PSME4 -13130.0 -13058.0
PSMF1 -12443.0 -3758.0
RAC1 -3223.0 -13385.0
RBM8A -8207.0 -1247.0
RBX1 -6001.0 -10254.0
RHOA -15122.0 -4532.0
RNPS1 -15843.0 -6534.0
ROBO1 -7350.0 -6372.0
ROBO2 -2751.0 -3170.0
ROBO3 -10190.0 -10095.0
RPL10A -4327.0 -16688.0
RPL10L -4672.0 1242.0
RPL11 -7730.0 -11362.0
RPL12 -1818.0 -7657.0
RPL13 -13096.0 -17048.0
RPL13A -1938.5 -10955.5
RPL14 -8334.0 -15519.0
RPL15 -13598.0 -15972.0
RPL17 -4720.0 -15113.0
RPL18 -6084.0 -16405.0
RPL18A -13854.0 -12314.0
RPL19 -9925.0 -950.0
RPL21 -9899.5 -13500.5
RPL22 -2661.0 -13474.0
RPL22L1 -2679.0 -16975.0
RPL23 -3278.0 -4599.0
RPL23A -8489.0 -13877.0
RPL24 813.0 329.0
RPL26 -7851.0 -14206.0
RPL26L1 -4159.0 -17223.0
RPL27 -10972.0 -14660.0
RPL27A -11040.0 -16640.0
RPL28 -7060.0 -12491.0
RPL29 -6766.0 -14551.0
RPL3 -4433.0 -6744.0
RPL30 -3473.0 -13276.0
RPL31 160.0 -9807.0
RPL32 -8290.0 -7245.0
RPL34 -3639.0 913.0
RPL35 -12031.0 -16424.0
RPL35A -563.0 -483.0
RPL36 -15878.0 -16971.0
RPL36AL -12581.0 -15545.0
RPL37 -5636.0 -11980.0
RPL37A -8914.0 -12749.0
RPL38 -3414.0 -3066.0
RPL39L -2329.0 -16531.0
RPL3L -13013.0 328.0
RPL4 -7696.0 199.0
RPL41 -8377.0 -15742.0
RPL5 1478.0 -13656.0
RPL6 718.0 -2953.0
RPL7 -11616.0 -15741.0
RPL7A -11184.0 -3709.0
RPL8 -16023.0 -13701.0
RPL9 -4066.0 -291.0
RPLP0 -7445.0 -14511.0
RPLP1 -5049.0 -3663.0
RPLP2 -14824.0 -14743.0
RPS10 -11363.0 -14602.0
RPS11 -12666.0 -8009.0
RPS12 -5554.0 -5380.0
RPS13 541.0 -12870.0
RPS14 -14985.0 -576.0
RPS15 -11816.0 -15841.0
RPS15A 1563.0 -10896.0
RPS16 -12775.0 -13973.0
RPS17 363.0 -17286.0
RPS18 -5492.0 -6509.0
RPS19 -4848.0 -463.0
RPS2 -8403.0 -13161.0
RPS20 -9963.0 -9064.0
RPS21 -14247.0 -15846.0
RPS23 -4455.0 -10331.0
RPS24 1255.0 -3232.0
RPS25 -2544.0 -11699.0
RPS26 802.0 -7841.0
RPS27 1722.0 -11381.0
RPS27A -11481.0 -2147.0
RPS27L -9482.0 -16569.0
RPS28 -12352.0 -15277.0
RPS29 -8298.0 -16523.0
RPS3 1404.0 -10369.0
RPS3A -10279.0 -15494.0
RPS5 -15070.0 -15693.0
RPS6 -16407.0 -6799.0
RPS7 -3124.0 -12481.0
RPS8 -9073.0 -1281.0
RPS9 -11982.0 -623.0
RPSA -4693.0 -3295.0
SEM1 -1388.0 -14801.0
SLIT1 -6428.0 -99.0
SLIT2 -4349.0 -3443.0
SLIT3 -1679.0 -4982.0
SOS1 -10061.0 -5272.0
SOS2 -13566.0 -16495.0
SRC -8945.0 -2260.0
SRGAP1 -2152.0 -10417.0
SRGAP2 1921.0 -2491.0
SRGAP3 212.0 -3328.0
UBA52 -10894.0 -4996.0
UBB -12784.0 -8060.0
UBC -11566.0 -692.0
UPF2 -5215.0 -9117.0
UPF3A -4036.0 -16210.0
USP33 -11185.0 -9658.0
VASP -1351.0 -13240.0
ZSWIM8 -10772.0 -11492.0



REACTOME_RRNA_PROCESSING

REACTOME_RRNA_PROCESSING
metric value
setSize 193
pMANOVA 3.16e-06
p.adjustMANOVA 0.000148
s.dist 0.217
s.Estill -0.0532
s.Novakovic -0.21
p.Estill 0.203
p.Novakovic 4.83e-07




Top 20 genes
Gene Estill Novakovic
TRMT112 -15892 -17246
RPL36 -15878 -16971
NIP7 -15328 -15460
RPS5 -15070 -15693
RPS21 -14247 -15846
RPL13 -13096 -17048
RPL8 -16023 -13701
RPLP2 -14824 -14743
RPL15 -13598 -15972
UTP4 -12761 -16727
RRP9 -14440 -14383
EXOSC6 -12471 -16303
WDR12 -14637 -13573
RPL35 -12031 -16424
RPL36AL -12581 -15545
MPHOSPH6 -12110 -16004
NOP2 -13475 -14287
RPS28 -12352 -15277
TSR3 -13343 -14106
RPS15 -11816 -15841

Click HERE to show all gene set members

All member genes
Estill Novakovic
BMS1 -8114.0 -1830.0
BOP1 -12104.0 -7587.0
BUD23 -15422.0 -10745.0
BYSL -10901.0 -7824.0
C1D -2204.0 -8106.0
CSNK1D -10315.0 -2827.0
CSNK1E -12689.0 -11824.0
DCAF13 -9156.0 -5558.0
DDX21 -8139.0 -12017.0
DDX47 -1790.0 -2387.0
DDX49 -4600.0 -8430.0
DDX52 -8138.0 -12957.0
DHX37 -2150.0 -5285.0
DIMT1 -1868.0 -12883.0
DIS3 -2692.0 -3659.0
EBNA1BP2 -3522.0 -3267.0
ELAC2 -14476.0 -11266.0
EMG1 -1928.0 -10969.0
ERI1 -8397.0 -8222.0
EXOSC1 -11535.0 -12332.0
EXOSC10 -11735.0 -4107.0
EXOSC2 -8230.0 -8207.0
EXOSC3 -3581.0 -16081.0
EXOSC4 -6412.0 -13941.0
EXOSC5 -14082.0 -9766.0
EXOSC6 -12471.0 -16303.0
EXOSC7 -9065.0 -6973.0
EXOSC8 -11683.0 -3776.0
EXOSC9 -8456.0 -7477.0
FAU -8361.0 -15762.0
FBL -10466.0 -1981.0
FCF1 -1801.0 -6814.0
FTSJ3 -9643.0 -12079.0
GAR1 -10289.0 -10526.0
GNL3 -569.0 -6917.0
HEATR1 -6450.0 -6818.0
IMP3 -9739.0 -14626.0
IMP4 -488.0 -3520.0
ISG20L2 -5205.0 -10925.0
KRR1 2095.0 -6080.0
LTV1 -9691.0 -6220.0
MPHOSPH10 -11654.0 -13392.0
MPHOSPH6 -12110.0 -16004.0
MRM1 -2362.0 -7108.0
MRM2 -4752.0 -14753.0
MRM3 -9327.0 -10610.0
MTERF4 -3698.0 -12190.0
MTREX -15180.0 -11259.0
NAT10 -2065.0 -662.0
NCL -1119.0 -11387.0
NHP2 -6740.0 -12267.0
NIP7 -15328.0 -15460.0
NOB1 -6653.0 -15190.0
NOC4L -12566.0 -8906.0
NOL11 -13708.0 -7588.0
NOL12 -4233.0 -5271.0
NOL6 1036.0 -9213.0
NOL9 -15751.0 -6965.0
NOP10 -4416.0 1326.0
NOP14 -6525.0 -7972.0
NOP2 -13475.0 -14287.0
NOP56 -4751.0 -9699.0
NOP58 -1224.0 -13035.0
NSUN4 -5053.0 -9573.0
PDCD11 -12738.0 -9602.0
PELP1 -2276.0 97.0
PES1 -2829.0 429.0
PNO1 -9426.0 -14472.0
PRORP -2590.0 -11245.0
PWP2 -16374.0 -4256.0
RBM28 -708.0 -11389.0
RCL1 -4953.0 -7784.0
RIOK1 -13823.0 -10020.0
RIOK2 -12639.0 -1643.0
RIOK3 -14847.0 -338.0
RPL10A -4327.0 -16688.0
RPL10L -4672.0 1242.0
RPL11 -7730.0 -11362.0
RPL12 -1818.0 -7657.0
RPL13 -13096.0 -17048.0
RPL13A -1938.5 -10955.5
RPL14 -8334.0 -15519.0
RPL15 -13598.0 -15972.0
RPL17 -4720.0 -15113.0
RPL18 -6084.0 -16405.0
RPL18A -13854.0 -12314.0
RPL19 -9925.0 -950.0
RPL21 -9899.5 -13500.5
RPL22 -2661.0 -13474.0
RPL22L1 -2679.0 -16975.0
RPL23 -3278.0 -4599.0
RPL23A -8489.0 -13877.0
RPL24 813.0 329.0
RPL26 -7851.0 -14206.0
RPL26L1 -4159.0 -17223.0
RPL27 -10972.0 -14660.0
RPL27A -11040.0 -16640.0
RPL28 -7060.0 -12491.0
RPL29 -6766.0 -14551.0
RPL3 -4433.0 -6744.0
RPL30 -3473.0 -13276.0
RPL31 160.0 -9807.0
RPL32 -8290.0 -7245.0
RPL34 -3639.0 913.0
RPL35 -12031.0 -16424.0
RPL35A -563.0 -483.0
RPL36 -15878.0 -16971.0
RPL36AL -12581.0 -15545.0
RPL37 -5636.0 -11980.0
RPL37A -8914.0 -12749.0
RPL38 -3414.0 -3066.0
RPL39L -2329.0 -16531.0
RPL3L -13013.0 328.0
RPL4 -7696.0 199.0
RPL41 -8377.0 -15742.0
RPL5 1478.0 -13656.0
RPL6 718.0 -2953.0
RPL7 -11616.0 -15741.0
RPL7A -11184.0 -3709.0
RPL8 -16023.0 -13701.0
RPL9 -4066.0 -291.0
RPLP0 -7445.0 -14511.0
RPLP1 -5049.0 -3663.0
RPLP2 -14824.0 -14743.0
RPP14 -8364.0 -10025.0
RPP21 -8006.0 -11507.0
RPP25 -3896.0 -16883.0
RPP30 -11196.0 -2239.0
RPP38 -5496.0 -16696.0
RPP40 -6839.0 -9297.0
RPS10 -11363.0 -14602.0
RPS11 -12666.0 -8009.0
RPS12 -5554.0 -5380.0
RPS13 541.0 -12870.0
RPS14 -14985.0 -576.0
RPS15 -11816.0 -15841.0
RPS15A 1563.0 -10896.0
RPS16 -12775.0 -13973.0
RPS17 363.0 -17286.0
RPS18 -5492.0 -6509.0
RPS19 -4848.0 -463.0
RPS2 -8403.0 -13161.0
RPS20 -9963.0 -9064.0
RPS21 -14247.0 -15846.0
RPS23 -4455.0 -10331.0
RPS24 1255.0 -3232.0
RPS25 -2544.0 -11699.0
RPS26 802.0 -7841.0
RPS27 1722.0 -11381.0
RPS27A -11481.0 -2147.0
RPS27L -9482.0 -16569.0
RPS28 -12352.0 -15277.0
RPS29 -8298.0 -16523.0
RPS3 1404.0 -10369.0
RPS3A -10279.0 -15494.0
RPS5 -15070.0 -15693.0
RPS6 -16407.0 -6799.0
RPS7 -3124.0 -12481.0
RPS8 -9073.0 -1281.0
RPS9 -11982.0 -623.0
RPSA -4693.0 -3295.0
RRP1 -10726.0 -13330.0
RRP36 -1521.0 -12565.0
RRP7A -6927.0 -15826.0
RRP9 -14440.0 -14383.0
SENP3 -4425.0 -16216.0
SNU13 -4140.0 -11984.0
TBL3 -13436.0 -6770.0
TEX10 -768.0 -9089.0
TFB1M -4717.0 -14189.0
THUMPD1 -6716.0 186.0
TRMT10C -5143.0 -14640.0
TRMT112 -15892.0 -17246.0
TSR1 -8085.0 -15825.0
TSR3 -13343.0 -14106.0
UBA52 -10894.0 -4996.0
UTP11 -3270.0 -12685.0
UTP14C 2455.0 208.0
UTP15 -10573.5 -12890.0
UTP18 -9890.0 -10957.0
UTP20 -10214.0 -6804.0
UTP25 -1275.0 -7555.0
UTP3 -1737.0 -4729.0
UTP4 -12761.0 -16727.0
UTP6 -8714.0 -4562.0
WDR12 -14637.0 -13573.0
WDR18 -14866.0 237.0
WDR3 -7575.0 -10583.0
WDR36 -564.0 -8116.0
WDR43 -15840.0 -10013.0
WDR46 -879.0 -6060.0
WDR75 -3171.0 -9088.0
XRN2 -11612.0 -14144.0



REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT
metric value
setSize 222
pMANOVA 3.57e-06
p.adjustMANOVA 0.000163
s.dist 0.213
s.Estill -0.103
s.Novakovic -0.187
p.Estill 0.00822
p.Novakovic 1.67e-06




Top 20 genes
Gene Estill Novakovic
FRAT2 -16189 -16880
FZD1 -15389 -17134
H3C12 -15164 -17158
FRAT1 -15919 -16245
FZD8 -15623 -16360
PSMA7 -15238 -16097
PSMD1 -15755 -15264
PPP2CA -16303 -14663
FZD2 -13506 -16588
RSPO3 -15479 -14436
H2AX -13329 -16764
PPP2R5D -13597 -16200
PSMB2 -15087 -14324
TCF7 -12947 -16291
CTNNB1 -16336 -12572
H3-3A -13934 -14636
H3C8 -15918 -12729
H2AZ2 -15177 -12968
H2BC26 -11379 -16861
H2AC8 -15265 -12472

Click HERE to show all gene set members

All member genes
Estill Novakovic
AKT1 -6145.0 -2432.0
AKT2 -12142.0 -6370.0
APC -6050.0 -14181.0
ASH2L -11017.0 -11523.0
AXIN1 -2253.0 -3623.0
AXIN2 -5471.0 -12043.0
BCL9 -7346.0 -7320.0
BCL9L -14169.0 -1405.0
BTRC -8741.0 -7184.0
CAV1 -6955.0 -12026.0
CBY1 -2062.0 -5338.0
CCDC88C -2997.0 -847.0
CDC73 -13398.0 -6655.0
CHD8 143.0 -3582.0
CREBBP 522.0 -5671.0
CSNK1A1 -11088.0 -12263.0
CSNK1E -12689.0 -11824.0
CSNK1G2 -7880.0 -3268.0
CSNK2A1 -10932.0 -4915.0
CSNK2A2 -15748.0 -7535.0
CSNK2B -367.0 -14595.0
CTBP1 -2060.0 -1573.0
CTNNB1 -16336.0 -12572.0
CTNNBIP1 -6182.0 -4149.0
CUL3 -14992.0 -6223.0
CXXC4 -12127.0 -7207.0
DACT1 -6838.0 -8325.0
DKK1 -11112.0 -12522.0
DKK2 -11644.0 -6644.0
DKK4 -2522.0 -8610.0
DVL1 -4354.0 -742.0
DVL2 -12133.0 183.0
DVL3 -3044.0 -11951.0
EP300 -1567.0 -10732.0
FRAT1 -15919.0 -16245.0
FRAT2 -16189.0 -16880.0
FZD1 -15389.0 -17134.0
FZD2 -13506.0 -16588.0
FZD4 -4517.0 -5806.0
FZD5 -2207.0 -14265.0
FZD6 -5553.0 -15755.0
FZD8 -15623.0 -16360.0
GSK3B -13275.0 -5625.0
H2AC14 -740.0 -6291.0
H2AC18 -10109.5 -16821.5
H2AC19 -10109.5 -16821.5
H2AC20 -9365.0 -421.0
H2AC4 -8682.0 -7652.0
H2AC6 -3772.0 -14402.0
H2AC7 -10309.0 -3529.5
H2AC8 -15265.0 -12472.0
H2AJ -360.0 -16792.0
H2AX -13329.0 -16764.0
H2AZ1 -10477.0 -10825.0
H2AZ2 -15177.0 -12968.0
H2BC1 930.5 1414.0
H2BC10 -12140.0 -5784.0
H2BC11 -4716.0 -15808.0
H2BC12 -3961.0 -14793.0
H2BC13 -11400.0 761.0
H2BC14 -1609.0 -8267.0
H2BC15 -2744.0 -168.0
H2BC17 -16322.0 -3166.0
H2BC21 -8996.0 -6316.0
H2BC26 -11379.0 -16861.0
H2BC3 -15205.0 -10594.0
H2BC4 -10641.0 -8955.0
H2BC5 -9533.0 315.0
H2BC6 -15206.0 266.0
H2BC7 -11776.0 -3529.5
H2BC8 -15228.0 -8541.0
H2BC9 -9951.5 -12902.5
H3-3A -13934.0 -14636.0
H3-3B -9143.0 -13971.0
H3-4 1657.0 1580.0
H3C1 -9230.0 -14629.0
H3C10 -3065.0 -374.0
H3C11 -7068.0 -13728.0
H3C12 -15164.0 -17158.0
H3C13 -4294.0 -15204.0
H3C2 -15289.0 -11553.0
H3C3 -6133.0 -14272.0
H3C4 -9971.0 -5667.0
H3C6 371.0 -17250.0
H3C7 -9951.5 -12902.5
H3C8 -15918.0 -12729.0
H4C1 -14459.0 -9617.0
H4C11 854.0 -16001.0
H4C12 -2120.0 -5312.0
H4C13 -334.0 -15402.0
H4C16 -7238.0 -8548.0
H4C2 -7763.0 -2343.0
H4C3 -5978.0 -7968.0
H4C4 -850.0 -16161.0
H4C5 -1971.0 -1886.0
H4C6 -9232.0 -16384.0
H4C8 -3484.0 -14606.0
H4C9 -10105.0 -17149.0
HDAC1 -9758.0 -7989.0
HECW1 -640.0 -2071.0
KAT5 -7750.0 -6812.0
KLHL12 -5005.0 -15369.0
KREMEN1 -15232.0 -8799.0
KREMEN2 -11169.0 -15528.0
LEF1 -6372.0 -10649.0
LEO1 -10346.0 -10399.0
LGR4 -3656.0 -8560.0
LGR5 -14737.0 -11460.0
LGR6 -8271.0 -1845.0
LRP5 -2418.0 -710.0
LRP6 -12135.0 -11760.0
MEN1 -6989.0 -12382.0
MYC -9179.0 -13967.0
PIP5K1B -4501.0 -9862.0
PPP2CA -16303.0 -14663.0
PPP2CB -790.0 302.0
PPP2R1A -5112.0 -15337.0
PPP2R1B -6245.0 -9456.0
PPP2R5A -14844.0 -2972.0
PPP2R5B -6416.0 -16175.0
PPP2R5C -2004.0 -7658.0
PPP2R5D -13597.0 -16200.0
PPP2R5E -6877.0 -9033.0
PSMA1 -8781.0 -2177.0
PSMA2 -7391.0 -13190.0
PSMA3 -543.0 -12585.0
PSMA4 -1489.0 -11130.0
PSMA5 -5612.0 -12086.0
PSMA6 -5453.0 -7068.0
PSMA7 -15238.0 -16097.0
PSMA8 -12998.0 1341.0
PSMB1 -7998.0 -12452.0
PSMB10 1546.0 -12645.0
PSMB11 -7675.0 461.0
PSMB2 -15087.0 -14324.0
PSMB3 -2943.0 -16574.0
PSMB4 -3092.0 -17193.0
PSMB5 -2173.0 -13304.0
PSMB6 -1270.0 -15778.0
PSMB7 1688.0 1166.0
PSMB8 251.0 -10098.0
PSMB9 -4477.0 -14712.0
PSMC1 -2414.0 -13145.0
PSMC2 -315.0 -2310.0
PSMC3 -7461.0 -17123.0
PSMC4 459.0 -4407.0
PSMC5 -9725.0 -12293.0
PSMC6 -7301.0 332.0
PSMD1 -15755.0 -15264.0
PSMD11 -6796.0 -15996.0
PSMD12 -13229.0 -1837.0
PSMD13 -9340.0 -12191.0
PSMD14 -9752.0 -14404.0
PSMD2 -5101.0 -4469.0
PSMD3 -6030.0 -12489.0
PSMD4 -6049.0 -14518.0
PSMD5 2564.0 -8724.0
PSMD6 -5979.0 -12939.0
PSMD7 -12233.0 -5710.0
PSMD8 -9781.0 -13888.0
PSMD9 -11408.0 -10645.0
PSME1 -9760.0 -16962.0
PSME2 67.0 -15711.0
PSME3 -4965.0 -13719.0
PSME4 -13130.0 -13058.0
PSMF1 -12443.0 -3758.0
PYGO1 -10081.0 -14909.0
PYGO2 -9666.0 -12521.0
RBBP5 -12137.0 -1239.0
RBX1 -6001.0 -10254.0
RNF146 -6320.0 -13864.0
RNF43 1844.0 -8903.0
RPS27A -11481.0 -2147.0
RSPO1 -10241.0 -13919.0
RSPO2 -12782.0 -13609.0
RSPO3 -15479.0 -14436.0
RSPO4 -13861.0 -13168.0
RUNX3 -5141.0 -10326.0
RUVBL1 -10977.0 -7680.0
RYK -5223.0 -7483.0
SEM1 -1388.0 -14801.0
SFRP1 -9003.0 -3040.0
SFRP2 -8687.0 -6576.0
SMARCA4 -3240.0 -918.0
SMURF2 -15717.0 -11044.0
SOST -11453.0 -9312.0
SOX13 -3962.0 -6256.0
SOX17 -11155.0 -16473.0
SOX2 -7419.0 -11925.0
SOX4 -11771.0 -12392.0
SOX6 -2900.0 -3369.0
SOX7 -5530.0 -12536.0
SOX9 -8023.0 -16121.0
TCF4 -3027.0 -8014.0
TCF7 -12947.0 -16291.0
TCF7L1 -4145.0 -5833.0
TCF7L2 -1672.0 -4487.0
TERT -1364.0 -2257.0
TLE1 -9787.0 -11778.0
TLE2 -6181.0 -6871.0
TLE3 -4389.0 -11403.0
TLE4 -6835.0 -11534.0
TNKS -8385.0 -9827.0
TNKS2 -15818.0 -11527.0
TRRAP 581.0 -6016.0
UBA52 -10894.0 -4996.0
UBB -12784.0 -8060.0
UBC -11566.0 -692.0
USP34 -15724.0 -7789.0
USP8 -9189.0 -6657.0
WIF1 -11701.0 -11677.0
WNT1 -10830.0 -11646.0
WNT3 -9909.0 -12278.0
WNT3A -4996.0 -5356.0
WNT4 -9267.0 -5134.0
WNT5A -2641.0 -9466.0
WNT8A -2071.0 -503.0
WNT8B -6894.0 -3090.0
WNT9A -13191.0 -1469.0
XPO1 -11418.0 -13329.0
YWHAZ -11791.0 -10782.0
ZNRF3 -4012.0 -7279.0



REACTOME_NONSENSE_MEDIATED_DECAY_NMD

REACTOME_NONSENSE_MEDIATED_DECAY_NMD
metric value
setSize 108
pMANOVA 4.71e-06
p.adjustMANOVA 0.000209
s.dist 0.276
s.Estill -0.0357
s.Novakovic -0.274
p.Estill 0.522
p.Novakovic 9.06e-07




Top 20 genes
Gene Estill Novakovic
RPL36 -15878.0 -16971
PNRC2 -15485.0 -16726
PPP2CA -16303.0 -14663
RPS5 -15070.0 -15693
RPS21 -14247.0 -15846
RPL13 -13096.0 -17048
RPL8 -16023.0 -13701
RPLP2 -14824.0 -14743
RPL15 -13598.0 -15972
RPL35 -12031.0 -16424
RPL36AL -12581.0 -15545
RPS28 -12352.0 -15277
RPS15 -11816.0 -15841
RPL27A -11040.0 -16640
RPL7 -11616.0 -15741
RPS16 -12775.0 -13973
RPL18A -13854.0 -12314
RPS10 -11363.0 -14602
NCBP1 -9559.5 -17039
RPL27 -10972.0 -14660

Click HERE to show all gene set members

All member genes
Estill Novakovic
CASC3 -11669.0 -3656.0
DCP1A -10322.0 -15177.0
EIF4A3 -30.0 -4961.0
EIF4G1 -1656.0 -6170.0
ETF1 -9521.0 -10565.0
FAU -8361.0 -15762.0
GSPT1 -12163.0 -2538.0
MAGOH -2775.0 -16629.0
MAGOHB -7797.0 -17140.0
NCBP1 -9559.5 -17039.0
NCBP2 -2050.0 -13946.0
PABPC1 -6557.0 -12965.0
PNRC2 -15485.0 -16726.0
PPP2CA -16303.0 -14663.0
PPP2R1A -5112.0 -15337.0
PPP2R2A -14638.0 -5917.0
RBM8A -8207.0 -1247.0
RNPS1 -15843.0 -6534.0
RPL10A -4327.0 -16688.0
RPL10L -4672.0 1242.0
RPL11 -7730.0 -11362.0
RPL12 -1818.0 -7657.0
RPL13 -13096.0 -17048.0
RPL13A -1938.5 -10955.5
RPL14 -8334.0 -15519.0
RPL15 -13598.0 -15972.0
RPL17 -4720.0 -15113.0
RPL18 -6084.0 -16405.0
RPL18A -13854.0 -12314.0
RPL19 -9925.0 -950.0
RPL21 -9899.5 -13500.5
RPL22 -2661.0 -13474.0
RPL22L1 -2679.0 -16975.0
RPL23 -3278.0 -4599.0
RPL23A -8489.0 -13877.0
RPL24 813.0 329.0
RPL26 -7851.0 -14206.0
RPL26L1 -4159.0 -17223.0
RPL27 -10972.0 -14660.0
RPL27A -11040.0 -16640.0
RPL28 -7060.0 -12491.0
RPL29 -6766.0 -14551.0
RPL3 -4433.0 -6744.0
RPL30 -3473.0 -13276.0
RPL31 160.0 -9807.0
RPL32 -8290.0 -7245.0
RPL34 -3639.0 913.0
RPL35 -12031.0 -16424.0
RPL35A -563.0 -483.0
RPL36 -15878.0 -16971.0
RPL36AL -12581.0 -15545.0
RPL37 -5636.0 -11980.0
RPL37A -8914.0 -12749.0
RPL38 -3414.0 -3066.0
RPL39L -2329.0 -16531.0
RPL3L -13013.0 328.0
RPL4 -7696.0 199.0
RPL41 -8377.0 -15742.0
RPL5 1478.0 -13656.0
RPL6 718.0 -2953.0
RPL7 -11616.0 -15741.0
RPL7A -11184.0 -3709.0
RPL8 -16023.0 -13701.0
RPL9 -4066.0 -291.0
RPLP0 -7445.0 -14511.0
RPLP1 -5049.0 -3663.0
RPLP2 -14824.0 -14743.0
RPS10 -11363.0 -14602.0
RPS11 -12666.0 -8009.0
RPS12 -5554.0 -5380.0
RPS13 541.0 -12870.0
RPS14 -14985.0 -576.0
RPS15 -11816.0 -15841.0
RPS15A 1563.0 -10896.0
RPS16 -12775.0 -13973.0
RPS17 363.0 -17286.0
RPS18 -5492.0 -6509.0
RPS19 -4848.0 -463.0
RPS2 -8403.0 -13161.0
RPS20 -9963.0 -9064.0
RPS21 -14247.0 -15846.0
RPS23 -4455.0 -10331.0
RPS24 1255.0 -3232.0
RPS25 -2544.0 -11699.0
RPS26 802.0 -7841.0
RPS27 1722.0 -11381.0
RPS27A -11481.0 -2147.0
RPS27L -9482.0 -16569.0
RPS28 -12352.0 -15277.0
RPS29 -8298.0 -16523.0
RPS3 1404.0 -10369.0
RPS3A -10279.0 -15494.0
RPS5 -15070.0 -15693.0
RPS6 -16407.0 -6799.0
RPS7 -3124.0 -12481.0
RPS8 -9073.0 -1281.0
RPS9 -11982.0 -623.0
RPSA -4693.0 -3295.0
SMG1 -1136.0 -10950.0
SMG5 -7650.0 -7428.0
SMG6 -1586.0 -6031.0
SMG7 -3787.0 -17180.0
SMG8 224.0 -16983.0
SMG9 -14689.0 -625.0
UBA52 -10894.0 -4996.0
UPF1 -8148.0 -2382.0
UPF2 -5215.0 -9117.0
UPF3A -4036.0 -16210.0



REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS
metric value
setSize 101
pMANOVA 7.89e-06
p.adjustMANOVA 0.000341
s.dist 0.303
s.Estill -0.137
s.Novakovic -0.27
p.Estill 0.0172
p.Novakovic 2.71e-06




Top 20 genes
Gene Estill Novakovic
POLR2L -16149.0 -16420.0
NUP37 -15153.0 -17285.0
H3C12 -15164.0 -17158.0
NUP153 -14779.0 -17257.0
H2AX -13329.0 -16764.0
H3-3A -13934.0 -14636.0
H3C8 -15918.0 -12729.0
H2AZ2 -15177.0 -12968.0
H2BC26 -11379.0 -16861.0
H2AC8 -15265.0 -12472.0
NUP155 -12129.0 -15214.0
TPR -12390.0 -14677.0
H3C2 -15289.0 -11553.0
RAN -10662.0 -16269.0
H4C9 -10105.0 -17149.0
H2AC18 -10109.5 -16821.5
H2AC19 -10109.5 -16821.5
H2BC3 -15205.0 -10594.0
POLR2C -9988.0 -16056.0
POM121 -13119.0 -11642.0

Click HERE to show all gene set members

All member genes
Estill Novakovic
AAAS -5233.0 -3868.0
AGO1 -747.0 -11588.0
AGO2 -1851.0 -1680.0
H2AC14 -740.0 -6291.0
H2AC18 -10109.5 -16821.5
H2AC19 -10109.5 -16821.5
H2AC20 -9365.0 -421.0
H2AC4 -8682.0 -7652.0
H2AC6 -3772.0 -14402.0
H2AC7 -10309.0 -3529.5
H2AC8 -15265.0 -12472.0
H2AJ -360.0 -16792.0
H2AX -13329.0 -16764.0
H2AZ1 -10477.0 -10825.0
H2AZ2 -15177.0 -12968.0
H2BC1 930.5 1414.0
H2BC10 -12140.0 -5784.0
H2BC11 -4716.0 -15808.0
H2BC12 -3961.0 -14793.0
H2BC13 -11400.0 761.0
H2BC14 -1609.0 -8267.0
H2BC15 -2744.0 -168.0
H2BC17 -16322.0 -3166.0
H2BC21 -8996.0 -6316.0
H2BC26 -11379.0 -16861.0
H2BC3 -15205.0 -10594.0
H2BC4 -10641.0 -8955.0
H2BC5 -9533.0 315.0
H2BC6 -15206.0 266.0
H2BC7 -11776.0 -3529.5
H2BC8 -15228.0 -8541.0
H2BC9 -9951.5 -12902.5
H3-3A -13934.0 -14636.0
H3-3B -9143.0 -13971.0
H3C1 -9230.0 -14629.0
H3C10 -3065.0 -374.0
H3C11 -7068.0 -13728.0
H3C12 -15164.0 -17158.0
H3C13 -4294.0 -15204.0
H3C2 -15289.0 -11553.0
H3C3 -6133.0 -14272.0
H3C4 -9971.0 -5667.0
H3C6 371.0 -17250.0
H3C7 -9951.5 -12902.5
H3C8 -15918.0 -12729.0
H4C1 -14459.0 -9617.0
H4C11 854.0 -16001.0
H4C12 -2120.0 -5312.0
H4C13 -334.0 -15402.0
H4C16 -7238.0 -8548.0
H4C2 -7763.0 -2343.0
H4C3 -5978.0 -7968.0
H4C4 -850.0 -16161.0
H4C5 -1971.0 -1886.0
H4C6 -9232.0 -16384.0
H4C8 -3484.0 -14606.0
H4C9 -10105.0 -17149.0
IPO8 -5973.0 -3747.0
NDC1 -11478.0 -8778.0
NUP107 -7236.0 -8001.0
NUP133 -2470.0 -9143.0
NUP153 -14779.0 -17257.0
NUP155 -12129.0 -15214.0
NUP160 -11625.0 -12148.0
NUP188 -7877.0 -15187.0
NUP205 -7637.0 -436.0
NUP210 -10939.0 -191.0
NUP214 -13610.0 -5777.0
NUP35 -1428.0 -7296.0
NUP37 -15153.0 -17285.0
NUP42 -8725.0 -15797.0
NUP43 -6734.0 -13552.0
NUP50 -14109.0 -5828.0
NUP54 -12929.0 -7747.0
NUP58 -9205.0 -15350.0
NUP62 -3466.0 -2332.0
NUP85 -4129.0 -11356.0
NUP88 -7189.0 -10830.0
NUP93 -3140.0 -9015.0
NUP98 -8145.0 -10870.0
POLR2A 281.0 -12598.0
POLR2B -6420.0 -12168.0
POLR2C -9988.0 -16056.0
POLR2D -5476.0 -17166.0
POLR2E -6353.0 -15885.0
POLR2F -11988.0 -11623.0
POLR2G 1063.0 -12103.0
POLR2H -12591.0 -11738.0
POLR2I -5956.0 -15772.0
POLR2J -11626.0 -4910.0
POLR2K -1330.0 590.0
POLR2L -16149.0 -16420.0
POM121 -13119.0 -11642.0
POM121C -3009.0 -6792.0
RAE1 -10699.0 -7730.0
RAN -10662.0 -16269.0
RANBP2 -8430.0 -15721.0
SEC13 -8604.0 -10471.0
SEH1L -8901.0 -14935.0
TNRC6A -9124.0 -9298.0
TPR -12390.0 -14677.0



REACTOME_CELLULAR_RESPONSE_TO_STARVATION

REACTOME_CELLULAR_RESPONSE_TO_STARVATION
metric value
setSize 148
pMANOVA 8.45e-06
p.adjustMANOVA 0.000356
s.dist 0.241
s.Estill -0.0713
s.Novakovic -0.23
p.Estill 0.134
p.Novakovic 1.39e-06




Top 20 genes
Gene Estill Novakovic
RPL36 -15878 -16971
LAMTOR2 -15827 -16936
ATP6V1E1 -15701 -16740
KICS2 -15615 -16083
MIOS -15826 -15769
CASTOR2 -14444 -17061
RPS5 -15070 -15693
RPS21 -14247 -15846
RPL13 -13096 -17048
CEBPB -15578 -14184
RPL8 -16023 -13701
RPLP2 -14824 -14743
RPL15 -13598 -15972
MLST8 -15381 -13231
RPL35 -12031 -16424
RPL36AL -12581 -15545
ATP6V0E2 -14863 -13012
RPS28 -12352 -15277
RPS15 -11816 -15841
RPL27A -11040 -16640

Click HERE to show all gene set members

All member genes
Estill Novakovic
ASNS -12523.0 -3499.0
ATF2 -6207.0 -6194.0
ATF3 -3655.0 -7904.0
ATF4 -2615.0 -14466.0
ATP6V0B -13617.0 -11086.0
ATP6V0C -13656.0 -9496.0
ATP6V0D1 -3181.0 -14043.0
ATP6V0D2 1818.0 477.0
ATP6V0E1 51.0 -7886.0
ATP6V0E2 -14863.0 -13012.0
ATP6V1A -14998.0 -3702.0
ATP6V1B1 -9405.0 -14749.0
ATP6V1B2 -12353.0 -5339.0
ATP6V1C1 -2923.0 -8310.0
ATP6V1C2 -5110.0 -6736.0
ATP6V1D -832.0 -10071.0
ATP6V1E1 -15701.0 -16740.0
ATP6V1E2 1998.0 1394.0
ATP6V1F -4404.0 1153.0
ATP6V1G1 -4860.0 -8958.0
ATP6V1G2 -11779.0 -10251.0
ATP6V1H -12053.0 -13165.0
BMT2 -9249.0 -919.0
CASTOR1 -9041.0 -9645.0
CASTOR2 -14444.0 -17061.0
CEBPB -15578.0 -14184.0
CEBPG -12298.0 -12515.0
DDIT3 -14204.0 -11300.0
DEPDC5 -9902.0 -1585.0
EIF2AK4 -3557.0 -15338.0
EIF2S1 -1610.0 -12288.0
EIF2S2 -9285.0 -8900.0
FAU -8361.0 -15762.0
FLCN -1896.0 -6564.0
FNIP1 -10727.0 -13964.0
FNIP2 -10595.0 -4951.0
GCN1 -14340.0 -6824.0
IMPACT -12435.0 -12470.0
ITFG2 -4230.0 278.0
KICS2 -15615.0 -16083.0
KPTN -7371.0 -13551.0
LAMTOR1 -4373.0 -1485.0
LAMTOR2 -15827.0 -16936.0
LAMTOR3 -9742.0 -9546.0
LAMTOR4 -3862.0 -10879.0
LAMTOR5 -5629.0 -15481.0
MIOS -15826.0 -15769.0
MLST8 -15381.0 -13231.0
MTOR 819.0 -8409.0
NPRL2 -11454.0 -11257.0
NPRL3 -2853.0 -4929.0
RHEB -4914.0 -7995.0
RPL10A -4327.0 -16688.0
RPL10L -4672.0 1242.0
RPL11 -7730.0 -11362.0
RPL12 -1818.0 -7657.0
RPL13 -13096.0 -17048.0
RPL13A -1938.5 -10955.5
RPL14 -8334.0 -15519.0
RPL15 -13598.0 -15972.0
RPL17 -4720.0 -15113.0
RPL18 -6084.0 -16405.0
RPL18A -13854.0 -12314.0
RPL19 -9925.0 -950.0
RPL21 -9899.5 -13500.5
RPL22 -2661.0 -13474.0
RPL22L1 -2679.0 -16975.0
RPL23 -3278.0 -4599.0
RPL23A -8489.0 -13877.0
RPL24 813.0 329.0
RPL26 -7851.0 -14206.0
RPL26L1 -4159.0 -17223.0
RPL27 -10972.0 -14660.0
RPL27A -11040.0 -16640.0
RPL28 -7060.0 -12491.0
RPL29 -6766.0 -14551.0
RPL3 -4433.0 -6744.0
RPL30 -3473.0 -13276.0
RPL31 160.0 -9807.0
RPL32 -8290.0 -7245.0
RPL34 -3639.0 913.0
RPL35 -12031.0 -16424.0
RPL35A -563.0 -483.0
RPL36 -15878.0 -16971.0
RPL36AL -12581.0 -15545.0
RPL37 -5636.0 -11980.0
RPL37A -8914.0 -12749.0
RPL38 -3414.0 -3066.0
RPL39L -2329.0 -16531.0
RPL3L -13013.0 328.0
RPL4 -7696.0 199.0
RPL41 -8377.0 -15742.0
RPL5 1478.0 -13656.0
RPL6 718.0 -2953.0
RPL7 -11616.0 -15741.0
RPL7A -11184.0 -3709.0
RPL8 -16023.0 -13701.0
RPL9 -4066.0 -291.0
RPLP0 -7445.0 -14511.0
RPLP1 -5049.0 -3663.0
RPLP2 -14824.0 -14743.0
RPS10 -11363.0 -14602.0
RPS11 -12666.0 -8009.0
RPS12 -5554.0 -5380.0
RPS13 541.0 -12870.0
RPS14 -14985.0 -576.0
RPS15 -11816.0 -15841.0
RPS15A 1563.0 -10896.0
RPS16 -12775.0 -13973.0
RPS17 363.0 -17286.0
RPS18 -5492.0 -6509.0
RPS19 -4848.0 -463.0
RPS2 -8403.0 -13161.0
RPS20 -9963.0 -9064.0
RPS21 -14247.0 -15846.0
RPS23 -4455.0 -10331.0
RPS24 1255.0 -3232.0
RPS25 -2544.0 -11699.0
RPS26 802.0 -7841.0
RPS27 1722.0 -11381.0
RPS27A -11481.0 -2147.0
RPS27L -9482.0 -16569.0
RPS28 -12352.0 -15277.0
RPS29 -8298.0 -16523.0
RPS3 1404.0 -10369.0
RPS3A -10279.0 -15494.0
RPS5 -15070.0 -15693.0
RPS6 -16407.0 -6799.0
RPS7 -3124.0 -12481.0
RPS8 -9073.0 -1281.0
RPS9 -11982.0 -623.0
RPSA -4693.0 -3295.0
RPTOR -686.0 -708.0
RRAGA -1430.0 -17105.0
RRAGC -5607.0 -14388.0
RRAGD -7560.0 -10498.0
SEC13 -8604.0 -10471.0
SEH1L -8901.0 -14935.0
SESN1 -14137.0 -12007.0
SESN2 -7923.0 -16070.0
SH3BP4 -1626.0 -3701.0
SLC38A9 -11447.0 -16016.0
SZT2 -9029.0 -11372.0
TCIRG1 -12084.0 -2207.0
TRIB3 -12860.0 -1982.0
UBA52 -10894.0 -4996.0
WDR24 -6510.0 -2724.0
WDR59 -491.0 -7344.0



REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION

REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION
metric value
setSize 294
pMANOVA 9.44e-06
p.adjustMANOVA 0.000388
s.dist 0.18
s.Estill -0.0948
s.Novakovic -0.153
p.Estill 0.00522
p.Novakovic 6.73e-06




Top 20 genes
Gene Estill Novakovic
LONRF1 -16371 -16639
KCTD6 -15793 -16502
KCTD7 -15612 -16307
RNF19B -15212 -16271
PSMA7 -15238 -16097
UBA3 -15541 -15740
PSMD1 -15755 -15264
MYLIP -14891 -16055
RCHY1 -14487 -16333
UBE2G2 -13994 -15767
HERC5 -15283 -14373
FBXL3 -15085 -14438
KLHL11 -14392 -15120
PSMB2 -15087 -14324
FBXL15 -14627 -14552
MKRN1 -14405 -14707
FBXL12 -13018 -16165
UBE2C -14095 -14424
TRIM37 -13239 -15250
UBE2E3 -14250 -13936

Click HERE to show all gene set members

All member genes
Estill Novakovic
ANAPC1 -2324.0 -5744
ANAPC10 -11343.0 -5816
ANAPC11 -15553.0 -3569
ANAPC13 -11852.0 -11956
ANAPC2 -8367.0 -1213
ANAPC4 -11051.0 -6188
ANAPC5 -7613.0 -11860
ANAPC7 -6389.0 -4274
AREL1 -794.0 -7683
ARIH2 -13110.0 -13982
ASB1 -1235.0 -4580
ASB10 -14072.0 -5200
ASB13 -2473.0 -8600
ASB14 694.0 -11373
ASB15 479.0 -6185
ASB16 -6912.0 -5686
ASB18 -2226.0 -1579
ASB2 -9442.0 -2012
ASB3 -5310.0 -8183
ASB4 2196.0 -1841
ASB5 -16095.0 -9100
ASB6 -4727.0 -5688
ASB7 -2419.0 -7083
ASB8 -9288.0 -9220
ATG7 -2263.0 -4731
BLMH -9688.0 -13351
BTBD1 -13443.0 -11526
BTBD6 -13710.0 -12731
BTRC -8741.0 -7184
CBLB -16316.0 -5170
CCNF -3247.0 -5612
CDC16 -3120.0 -6337
CDC20 -14422.0 -10269
CDC23 -4732.0 -5268
CDC26 -5432.0 -868
CDC27 -8038.0 -11129
CDC34 -11242.0 -5868
CUL1 -2215.0 449
CUL2 -3906.0 -4879
CUL3 -14992.0 -6223
CUL5 -843.0 -13119
CUL7 -3055.0 -10083
DCAF1 -1171.0 -14036
DET1 -463.0 -1165
DTX3L -8050.0 -14254
DZIP3 -10626.0 -8109
ELOB -10647.0 -14069
ELOC -661.0 -10616
FBXL12 -13018.0 -16165
FBXL13 -3363.0 -10192
FBXL14 -8001.0 -4178
FBXL15 -14627.0 -14552
FBXL16 -7342.0 -6082
FBXL18 -3865.0 -1826
FBXL19 -6424.0 -9915
FBXL20 -16016.0 -6383
FBXL22 -9591.0 -14869
FBXL3 -15085.0 -14438
FBXL4 -13281.0 -6552
FBXL5 -12749.0 -14140
FBXL7 -618.0 -4837
FBXL8 -10674.0 -14990
FBXO10 245.0 -2014
FBXO11 -12169.0 -4458
FBXO15 -3353.0 -8878
FBXO17 -10324.0 -11787
FBXO2 -14249.0 -6703
FBXO21 -7794.0 -8178
FBXO22 -6083.0 -8731
FBXO27 -15881.0 -2987
FBXO30 -10281.0 -16762
FBXO31 -10323.0 -10703
FBXO32 -10663.0 -12770
FBXO4 -15943.0 -11926
FBXO40 -9.0 -5723
FBXO41 -4231.0 -134
FBXO44 -13523.0 23
FBXO6 -8972.0 -15198
FBXO7 -10825.0 -13283
FBXO9 -13450.0 -10603
FBXW10 1610.0 -9749
FBXW11 -2863.0 -8621
FBXW12 -191.0 -2608
FBXW2 -11571.0 -11821
FBXW4 -3900.0 -10605
FBXW5 -5600.0 -15276
FBXW7 -13298.0 -13607
FBXW8 651.0 -8606
FBXW9 -14054.0 -7302
FZR1 -7455.0 -2900
GAN -1814.0 -6556
GLMN -5478.5 -14907
HACE1 -6451.0 -16595
HECTD1 -14642.0 -11477
HECTD2 -4136.0 -16875
HECTD3 -15278.0 -11280
HECW2 -7039.0 -11002
HERC1 -7553.0 -8570
HERC2 1179.0 -69
HERC3 -7516.0 -11253
HERC4 -10904.0 -8509
HERC5 -15283.0 -14373
HERC6 -11457.0 -1804
ITCH -4315.0 -7177
KBTBD6 -604.0 -13292
KBTBD7 -7694.0 -10371
KBTBD8 -2622.0 -13598
KCTD6 -15793.0 -16502
KCTD7 -15612.0 -16307
KEAP1 -9462.0 -12683
KLHL11 -14392.0 -15120
KLHL2 -7334.0 -9277
KLHL20 -8702.0 -14496
KLHL21 -8261.0 -6666
KLHL22 -6799.0 -10735
KLHL25 -5767.0 -10393
KLHL3 -2499.0 -4411
KLHL42 -7230.0 -3198
KLHL5 -7215.0 -15968
KLHL9 -3267.0 -15897
LMO7 -200.0 -8053
LNPEP -15354.0 -8734
LNX1 -399.0 -783
LONRF1 -16371.0 -16639
LRR1 -12468.0 -8236
LRRC41 -8084.0 -10466
LRSAM1 -3297.0 -6123
LTN1 -6628.0 -6486
MEX3C -11946.0 -15362
MGRN1 -4696.0 -394
MIB2 -12816.0 -7212
MKRN1 -14405.0 -14707
MYLIP -14891.0 -16055
NEDD4 -8669.0 -4465
NEDD4L -1262.0 -6491
NPEPPS -3012.0 -3841
PJA2 -12259.0 -10937
PRKN -309.0 -1304
PSMA1 -8781.0 -2177
PSMA2 -7391.0 -13190
PSMA3 -543.0 -12585
PSMA4 -1489.0 -11130
PSMA5 -5612.0 -12086
PSMA6 -5453.0 -7068
PSMA7 -15238.0 -16097
PSMA8 -12998.0 1341
PSMB1 -7998.0 -12452
PSMB10 1546.0 -12645
PSMB11 -7675.0 461
PSMB2 -15087.0 -14324
PSMB3 -2943.0 -16574
PSMB4 -3092.0 -17193
PSMB5 -2173.0 -13304
PSMB6 -1270.0 -15778
PSMB7 1688.0 1166
PSMB8 251.0 -10098
PSMB9 -4477.0 -14712
PSMC1 -2414.0 -13145
PSMC2 -315.0 -2310
PSMC3 -7461.0 -17123
PSMC4 459.0 -4407
PSMC5 -9725.0 -12293
PSMC6 -7301.0 332
PSMD1 -15755.0 -15264
PSMD11 -6796.0 -15996
PSMD12 -13229.0 -1837
PSMD13 -9340.0 -12191
PSMD14 -9752.0 -14404
PSMD2 -5101.0 -4469
PSMD3 -6030.0 -12489
PSMD4 -6049.0 -14518
PSMD5 2564.0 -8724
PSMD6 -5979.0 -12939
PSMD7 -12233.0 -5710
PSMD8 -9781.0 -13888
PSMD9 -11408.0 -10645
PSME1 -9760.0 -16962
PSME2 67.0 -15711
PSME3 -4965.0 -13719
PSME4 -13130.0 -13058
PSMF1 -12443.0 -3758
RBBP6 -9778.0 -14351
RBCK1 -9601.0 -17038
RBX1 -6001.0 -10254
RCHY1 -14487.0 -16333
RNF111 -6111.0 -6826
RNF114 -6097.0 -7515
RNF115 -11353.0 -15993
RNF123 -13938.0 -11872
RNF126 -10980.0 -12348
RNF130 -2912.0 -6583
RNF138 -9714.0 -16344
RNF14 -15057.0 -321
RNF144B -9509.0 -7044
RNF182 -6559.0 -4865
RNF19A -10012.0 -3769
RNF19B -15212.0 -16271
RNF213 521.0 -3454
RNF217 -8287.0 -6995
RNF220 -3339.0 -4815
RNF25 -351.0 -15912
RNF34 -10150.0 -10107
RNF4 -9599.0 -3392
RNF41 -13589.0 -8962
RNF6 -8913.0 -10261
RNF7 -15861.0 -4714
RPS27A -11481.0 -2147
SEM1 -1388.0 -14801
SH3RF1 458.0 -10538
SIAH1 -13529.0 -14243
SIAH2 -7546.0 -1410
SKP1 -9613.0 -15257
SKP2 -3788.0 -6780
SMURF1 -974.0 -3344
SMURF2 -15717.0 -11044
SOCS1 -7986.0 -15087
SOCS3 -8896.0 -17163
SPSB1 -5094.0 -2850
SPSB2 -7743.0 -17169
SPSB4 -12107.0 -5718
STUB1 -7361.0 -1554
THOP1 -5181.0 -7731
TPP2 -13255.0 -12390
TRAF7 -4878.0 -8648
TRAIP -15561.0 -10513
TRIM11 -10438.0 -16120
TRIM21 2217.0 -4632
TRIM32 -13206.0 -11127
TRIM36 -12431.0 -6768
TRIM37 -13239.0 -15250
TRIM39 497.0 -7834
TRIM4 -8264.0 -3720
TRIM41 -11480.0 -13910
TRIM50 -2235.0 1205
TRIM63 -13519.0 -825
TRIM69 -3802.0 -4753
TRIM71 -1595.0 -6836
TRIM9 -8755.0 -9078
TRIP12 -5071.0 -11211
UBA3 -15541.0 -15740
UBA5 -8091.0 -14709
UBA52 -10894.0 -4996
UBA6 -9789.0 -11243
UBA7 -12547.0 -6664
UBAC1 -257.0 -6448
UBB -12784.0 -8060
UBC -11566.0 -692
UBE2B -11942.0 -10699
UBE2C -14095.0 -14424
UBE2D1 -9905.0 -15085
UBE2D2 -10137.0 -16684
UBE2D3 -4713.0 -14451
UBE2D4 -14166.0 -11050
UBE2E1 -7722.0 -8346
UBE2E2 -10203.0 -12117
UBE2E3 -14250.0 -13936
UBE2F -12892.0 -7280
UBE2G1 -7779.0 -13836
UBE2G2 -13994.0 -15767
UBE2H -2377.0 -10682
UBE2J1 -13675.0 -8033
UBE2J2 -1793.0 -4300
UBE2K -12890.0 -7960
UBE2L3 -5074.0 -2077
UBE2L6 -14498.0 -11683
UBE2M -12213.0 -9760
UBE2N -9458.0 -16754
UBE2O -219.0 -1983
UBE2Q1 -12258.0 -15777
UBE2Q2 -8203.0 -7541
UBE2R2 299.0 -9908
UBE2S -10702.0 -8077
UBE2U -827.0 842
UBE2V1 -11998.0 -9500
UBE2V2 -16133.0 -1676
UBE2W -1582.0 -11839
UBE2Z -11861.0 -7806
UBE3A -9373.0 -16191
UBE3B -4413.0 -1663
UBE3C -4895.0 -4176
UBE3D -8242.0 -9682
UBE4A -5811.0 -11161
UBOX5 -10880.0 -12241
UBR1 -290.0 -8251
UBR2 -13777.0 -13054
UBR4 -2940.0 -4783
UFL1 -47.0 -3755
UNKL -5763.0 -660
VHL -9255.0 -285
WSB1 -731.0 -16402
WWP1 -10974.0 -13041
ZBTB16 -3915.0 -3363
ZNRF1 -6104.0 476
ZNRF2 -8381.0 -10560



REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
metric value
setSize 88
pMANOVA 1.09e-05
p.adjustMANOVA 0.000431
s.dist 0.293
s.Estill -0.0317
s.Novakovic -0.291
p.Estill 0.608
p.Novakovic 2.3e-06




Top 20 genes
Gene Estill Novakovic
RPL36 -15878 -16971
RPS5 -15070 -15693
RPS21 -14247 -15846
RPL13 -13096 -17048
RPL8 -16023 -13701
RPLP2 -14824 -14743
RPL15 -13598 -15972
EEF1A2 -12865 -15926
RPL35 -12031 -16424
RPL36AL -12581 -15545
RPS28 -12352 -15277
RPS15 -11816 -15841
RPL27A -11040 -16640
RPL7 -11616 -15741
RPS16 -12775 -13973
RPL18A -13854 -12314
RPS10 -11363 -14602
RPL27 -10972 -14660
RPS3A -10279 -15494
RPS27L -9482 -16569

Click HERE to show all gene set members

All member genes
Estill Novakovic
EEF1A1 -7263.0 -14577.0
EEF1A2 -12865.0 -15926.0
EEF1B2 -8133.0 -12805.0
EEF1D -8984.0 -15865.0
EEF1G 2157.0 -13285.0
EEF2 -12638.0 -4822.0
FAU -8361.0 -15762.0
RPL10A -4327.0 -16688.0
RPL10L -4672.0 1242.0
RPL11 -7730.0 -11362.0
RPL12 -1818.0 -7657.0
RPL13 -13096.0 -17048.0
RPL13A -1938.5 -10955.5
RPL14 -8334.0 -15519.0
RPL15 -13598.0 -15972.0
RPL17 -4720.0 -15113.0
RPL18 -6084.0 -16405.0
RPL18A -13854.0 -12314.0
RPL19 -9925.0 -950.0
RPL21 -9899.5 -13500.5
RPL22 -2661.0 -13474.0
RPL22L1 -2679.0 -16975.0
RPL23 -3278.0 -4599.0
RPL23A -8489.0 -13877.0
RPL24 813.0 329.0
RPL26 -7851.0 -14206.0
RPL26L1 -4159.0 -17223.0
RPL27 -10972.0 -14660.0
RPL27A -11040.0 -16640.0
RPL28 -7060.0 -12491.0
RPL29 -6766.0 -14551.0
RPL3 -4433.0 -6744.0
RPL30 -3473.0 -13276.0
RPL31 160.0 -9807.0
RPL32 -8290.0 -7245.0
RPL34 -3639.0 913.0
RPL35 -12031.0 -16424.0
RPL35A -563.0 -483.0
RPL36 -15878.0 -16971.0
RPL36AL -12581.0 -15545.0
RPL37 -5636.0 -11980.0
RPL37A -8914.0 -12749.0
RPL38 -3414.0 -3066.0
RPL39L -2329.0 -16531.0
RPL3L -13013.0 328.0
RPL4 -7696.0 199.0
RPL41 -8377.0 -15742.0
RPL5 1478.0 -13656.0
RPL6 718.0 -2953.0
RPL7 -11616.0 -15741.0
RPL7A -11184.0 -3709.0
RPL8 -16023.0 -13701.0
RPL9 -4066.0 -291.0
RPLP0 -7445.0 -14511.0
RPLP1 -5049.0 -3663.0
RPLP2 -14824.0 -14743.0
RPS10 -11363.0 -14602.0
RPS11 -12666.0 -8009.0
RPS12 -5554.0 -5380.0
RPS13 541.0 -12870.0
RPS14 -14985.0 -576.0
RPS15 -11816.0 -15841.0
RPS15A 1563.0 -10896.0
RPS16 -12775.0 -13973.0
RPS17 363.0 -17286.0
RPS18 -5492.0 -6509.0
RPS19 -4848.0 -463.0
RPS2 -8403.0 -13161.0
RPS20 -9963.0 -9064.0
RPS21 -14247.0 -15846.0
RPS23 -4455.0 -10331.0
RPS24 1255.0 -3232.0
RPS25 -2544.0 -11699.0
RPS26 802.0 -7841.0
RPS27 1722.0 -11381.0
RPS27A -11481.0 -2147.0
RPS27L -9482.0 -16569.0
RPS28 -12352.0 -15277.0
RPS29 -8298.0 -16523.0
RPS3 1404.0 -10369.0
RPS3A -10279.0 -15494.0
RPS5 -15070.0 -15693.0
RPS6 -16407.0 -6799.0
RPS7 -3124.0 -12481.0
RPS8 -9073.0 -1281.0
RPS9 -11982.0 -623.0
RPSA -4693.0 -3295.0
UBA52 -10894.0 -4996.0



REACTOME_RESPIRATORY_ELECTRON_TRANSPORT

REACTOME_RESPIRATORY_ELECTRON_TRANSPORT
metric value
setSize 90
pMANOVA 1.13e-05
p.adjustMANOVA 0.000431
s.dist 0.294
s.Estill -0.049
s.Novakovic -0.29
p.Estill 0.421
p.Novakovic 1.99e-06




Top 20 genes
Gene Estill Novakovic
NDUFA6 -14150 -16892
COX14 -15402 -15339
NDUFV2 -13182 -16649
ETFA -13277 -16406
SCO1 -13917 -15055
CYC1 -14875 -13374
SCO2 -15098 -13166
SURF1 -15514 -12618
NDUFAF5 -15596 -12181
ETFDH -12171 -15530
NDUFA3 -12400 -14967
COX5B -14297 -12160
COX11 -10902 -15866
COX5A -12320 -13007
COX7A2L -12857 -12460
NDUFB10 -12869 -12218
CYCS -13068 -11301
COX4I1 -8427 -17276
COX20 -9445 -15182
COX7C -11305 -12041

Click HERE to show all gene set members

All member genes
Estill Novakovic
ACAD9 -10540.0 -11360.0
COA1 -6143.0 -9072.0
COQ10A -3932.0 -7027.0
COQ10B -16021.0 -8221.0
COX11 -10902.0 -15866.0
COX14 -15402.0 -15339.0
COX16 -10443.0 134.0
COX18 -14154.0 -9252.0
COX19 -8594.0 -5715.0
COX20 -9445.0 -15182.0
COX4I1 -8427.0 -17276.0
COX5A -12320.0 -13007.0
COX5B -14297.0 -12160.0
COX6A1 -2855.0 -15071.0
COX6B1 -4301.0 -9406.0
COX6C -6273.0 -2535.0
COX7A2L -12857.0 -12460.0
COX7C -11305.0 -12041.0
COX8A 1645.0 -16534.0
CYC1 -14875.0 -13374.0
CYCS -13068.0 -11301.0
ECSIT -5551.0 -14185.0
ETFA -13277.0 -16406.0
ETFB -4797.0 -7538.0
ETFDH -12171.0 -15530.0
LRPPRC 1909.0 -6137.0
NDUFA10 -7174.0 -14744.0
NDUFA11 -5001.0 -8180.0
NDUFA12 -3151.0 -13242.0
NDUFA13 -12987.0 -5608.0
NDUFA2 -1203.0 -680.0
NDUFA3 -12400.0 -14967.0
NDUFA4 -7632.0 -13255.0
NDUFA5 1936.0 -2847.0
NDUFA6 -14150.0 -16892.0
NDUFA7 -10191.0 -11310.0
NDUFA8 -8329.5 -4531.0
NDUFA9 -8325.0 -14355.0
NDUFAB1 -7899.0 -5537.0
NDUFAF1 -1578.0 -4840.0
NDUFAF2 -4843.0 -2830.0
NDUFAF3 -2795.0 -15109.0
NDUFAF4 -10078.0 -12078.0
NDUFAF5 -15596.0 -12181.0
NDUFAF6 -5395.0 -3518.0
NDUFAF7 -8108.0 -14716.0
NDUFB1 -7712.0 -15971.0
NDUFB10 -12869.0 -12218.0
NDUFB2 -13672.0 -6873.0
NDUFB3 -567.0 -13200.0
NDUFB4 -10415.0 -12831.0
NDUFB5 -956.0 -15790.0
NDUFB6 985.0 -527.0
NDUFB7 -8437.0 -12378.0
NDUFB8 -1760.0 -10491.0
NDUFB9 -7078.0 -6396.0
NDUFC1 -11387.0 -8669.0
NDUFC2 -4484.0 -13141.0
NDUFS1 -6870.0 -16459.0
NDUFS2 -10178.0 -1790.0
NDUFS3 -3424.0 -16573.0
NDUFS4 -151.0 -4779.0
NDUFS5 -793.0 -25.0
NDUFS6 -3812.0 -8278.0
NDUFS7 -7919.0 -12307.0
NDUFS8 -9380.0 -8911.0
NDUFV1 -6847.0 -13078.0
NDUFV2 -13182.0 -16649.0
NDUFV3 -6044.0 -14913.0
NUBPL -4480.0 -3541.0
SCO1 -13917.0 -15055.0
SCO2 -15098.0 -13166.0
SDHA -2270.0 -534.0
SDHB 805.0 -13726.0
SDHC -7568.0 -16770.0
SDHD -9247.5 -11433.5
SURF1 -15514.0 -12618.0
TACO1 -1219.0 -3712.0
TIMMDC1 -7103.0 -7457.0
TMEM126B -4224.0 -13249.0
TMEM186 -7550.0 -16914.0
TRAP1 -2727.0 -8701.0
UQCR10 -7069.0 -17114.0
UQCR11 -4968.0 -6613.0
UQCRB -5109.0 -9427.0
UQCRC1 -1297.0 -5101.0
UQCRC2 -9513.0 -5738.0
UQCRFS1 -9449.0 -13526.0
UQCRH -4053.0 -9223.0
UQCRQ -486.0 -12784.0



REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM
metric value
setSize 78
pMANOVA 1.13e-05
p.adjustMANOVA 0.000431
s.dist 0.346
s.Estill -0.19
s.Novakovic -0.289
p.Estill 0.00366
p.Novakovic 1.06e-05




Top 20 genes
Gene Estill Novakovic
NUP37 -15153.0 -17285
NUP153 -14779.0 -17257
SRSF2 -14070.0 -17242
SRSF4 -15695.0 -14432
NXT1 -12398.0 -17072
FIP1L1 -12218.0 -16714
THOC7 -15935.0 -12396
SRSF9 -11326.0 -17076
U2AF1 -13274.0 -14544
NUP155 -12129.0 -15214
TPR -12390.0 -14677
U2AF2 -11577.0 -15695
THOC1 -13496.0 -12931
SRRM1 -15455.0 -10860
NCBP1 -9559.5 -17039
SLBP -10454.0 -14847
POM121 -13119.0 -11642
NUP58 -9205.0 -15350
NUP160 -11625.0 -12148
NUP42 -8725.0 -15797

Click HERE to show all gene set members

All member genes
Estill Novakovic
AAAS -5233.0 -3868
ALYREF -15271.0 -5872
CASC3 -11669.0 -3656
CDC40 -12577.0 -1236
CHTOP -9116.0 -7345
CPSF1 -8024.0 -3809
CPSF2 -7994.0 -16679
CPSF3 -8471.0 -11192
CPSF4 -8835.0 -13204
DDX39A -7150.0 -11299
DHX38 -1782.0 -11608
EIF4A3 -30.0 -4961
EIF4E -5903.0 -11598
FIP1L1 -12218.0 -16714
FYTTD1 -15501.0 -6181
GLE1 -3232.0 -7220
MAGOH -2775.0 -16629
MAGOHB -7797.0 -17140
NCBP1 -9559.5 -17039
NCBP2 -2050.0 -13946
NDC1 -11478.0 -8778
NUP107 -7236.0 -8001
NUP133 -2470.0 -9143
NUP153 -14779.0 -17257
NUP155 -12129.0 -15214
NUP160 -11625.0 -12148
NUP188 -7877.0 -15187
NUP205 -7637.0 -436
NUP210 -10939.0 -191
NUP214 -13610.0 -5777
NUP35 -1428.0 -7296
NUP37 -15153.0 -17285
NUP42 -8725.0 -15797
NUP43 -6734.0 -13552
NUP50 -14109.0 -5828
NUP54 -12929.0 -7747
NUP58 -9205.0 -15350
NUP62 -3466.0 -2332
NUP85 -4129.0 -11356
NUP88 -7189.0 -10830
NUP93 -3140.0 -9015
NUP98 -8145.0 -10870
NXF1 -8852.0 -11115
NXT1 -12398.0 -17072
POLDIP3 -15594.0 -7119
POM121 -13119.0 -11642
POM121C -3009.0 -6792
RAE1 -10699.0 -7730
RANBP2 -8430.0 -15721
RBM8A -8207.0 -1247
RNPS1 -15843.0 -6534
SARNP -3441.0 -1564
SEC13 -8604.0 -10471
SEH1L -8901.0 -14935
SLBP -10454.0 -14847
SLU7 -310.0 -11064
SRRM1 -15455.0 -10860
SRSF1 -1936.0 -13625
SRSF11 -13230.0 -9481
SRSF2 -14070.0 -17242
SRSF3 -8788.0 -9919
SRSF4 -15695.0 -14432
SRSF5 -7324.0 -3316
SRSF6 -10229.0 -12794
SRSF7 -5755.0 -13406
SRSF9 -11326.0 -17076
SYMPK -3587.0 -9784
THOC1 -13496.0 -12931
THOC3 1025.0 -6860
THOC5 -7076.0 -13735
THOC6 -9681.0 -2837
THOC7 -15935.0 -12396
TPR -12390.0 -14677
U2AF1 -13274.0 -14544
U2AF1L4 -1258.0 -10948
U2AF2 -11577.0 -15695
WDR33 -4585.0 -13497
ZC3H11A -6761.0 -6913



REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS

REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS
metric value
setSize 113
pMANOVA 1.22e-05
p.adjustMANOVA 0.000454
s.dist 0.277
s.Estill -0.107
s.Novakovic -0.255
p.Estill 0.0491
p.Novakovic 2.72e-06




Top 20 genes
Gene Estill Novakovic
POLR2L -16149.0 -16420.0
H3C12 -15164.0 -17158.0
H2AX -13329.0 -16764.0
H3-3A -13934.0 -14636.0
H3C8 -15918.0 -12729.0
H2AZ2 -15177.0 -12968.0
HOXB4 -11560.0 -16990.0
HOXD3 -13289.0 -14775.0
YY1 -16108.0 -12034.0
PCGF2 -13952.0 -13875.0
HDAC3 -13458.0 -14340.0
H2BC26 -11379.0 -16861.0
H2AC8 -15265.0 -12472.0
H3C2 -15289.0 -11553.0
H4C9 -10105.0 -17149.0
H2AC18 -10109.5 -16821.5
H2AC19 -10109.5 -16821.5
PAX6 -12567.0 -13345.0
MAFB -9506.0 -17202.0
H2BC3 -15205.0 -10594.0

Click HERE to show all gene set members

All member genes
Estill Novakovic
AJUBA -4874.0 -10340.0
ASH2L -11017.0 -11523.0
CNOT6 -7806.0 -3349.0
CNOT9 -5316.0 -4616.0
CREBBP 522.0 -5671.0
CTCF -9366.0 -5091.0
EED -10652.0 -4813.0
EGR2 -10679.0 -11611.0
EP300 -1567.0 -10732.0
EZH2 -5256.0 -15114.0
H2AC14 -740.0 -6291.0
H2AC18 -10109.5 -16821.5
H2AC19 -10109.5 -16821.5
H2AC20 -9365.0 -421.0
H2AC4 -8682.0 -7652.0
H2AC6 -3772.0 -14402.0
H2AC7 -10309.0 -3529.5
H2AC8 -15265.0 -12472.0
H2AJ -360.0 -16792.0
H2AX -13329.0 -16764.0
H2AZ1 -10477.0 -10825.0
H2AZ2 -15177.0 -12968.0
H2BC1 930.5 1414.0
H2BC10 -12140.0 -5784.0
H2BC11 -4716.0 -15808.0
H2BC12 -3961.0 -14793.0
H2BC13 -11400.0 761.0
H2BC14 -1609.0 -8267.0
H2BC15 -2744.0 -168.0
H2BC17 -16322.0 -3166.0
H2BC21 -8996.0 -6316.0
H2BC26 -11379.0 -16861.0
H2BC3 -15205.0 -10594.0
H2BC4 -10641.0 -8955.0
H2BC5 -9533.0 315.0
H2BC6 -15206.0 266.0
H2BC7 -11776.0 -3529.5
H2BC8 -15228.0 -8541.0
H2BC9 -9951.5 -12902.5
H3-3A -13934.0 -14636.0
H3-3B -9143.0 -13971.0
H3C1 -9230.0 -14629.0
H3C10 -3065.0 -374.0
H3C11 -7068.0 -13728.0
H3C12 -15164.0 -17158.0
H3C13 -4294.0 -15204.0
H3C2 -15289.0 -11553.0
H3C3 -6133.0 -14272.0
H3C4 -9971.0 -5667.0
H3C6 371.0 -17250.0
H3C7 -9951.5 -12902.5
H3C8 -15918.0 -12729.0
H4C1 -14459.0 -9617.0
H4C11 854.0 -16001.0
H4C12 -2120.0 -5312.0
H4C13 -334.0 -15402.0
H4C16 -7238.0 -8548.0
H4C2 -7763.0 -2343.0
H4C3 -5978.0 -7968.0
H4C4 -850.0 -16161.0
H4C5 -1971.0 -1886.0
H4C6 -9232.0 -16384.0
H4C8 -3484.0 -14606.0
H4C9 -10105.0 -17149.0
HDAC3 -13458.0 -14340.0
HOXA1 -758.0 -13844.0
HOXA2 1661.0 -8934.0
HOXA3 510.0 -5318.0
HOXA4 -3937.0 -13826.0
HOXB1 1945.0 -2677.0
HOXB2 -3094.0 -16099.0
HOXB3 499.0 -2457.0
HOXB4 -11560.0 -16990.0
HOXC4 -6348.0 -13796.0
HOXD1 -6433.0 -4853.0
HOXD3 -13289.0 -14775.0
HOXD4 -3388.0 -7098.0
JUN -12813.0 -12417.0
KMT2C -8906.0 -7703.0
MAFB -9506.0 -17202.0
MEIS1 -12040.0 -10951.0
NCOA3 -8655.0 -10827.0
NCOA6 -6671.0 -7768.0
NCOR1 -12162.0 -4890.0
PAGR1 -2577.0 -13445.0
PAX6 -12567.0 -13345.0
PAXIP1 -15566.0 -9616.0
PBX1 1609.0 -9973.0
PCGF2 -13952.0 -13875.0
PIAS2 -8953.0 -15890.0
PKNOX1 -10612.0 -12276.0
POLR2A 281.0 -12598.0
POLR2B -6420.0 -12168.0
POLR2C -9988.0 -16056.0
POLR2D -5476.0 -17166.0
POLR2E -6353.0 -15885.0
POLR2F -11988.0 -11623.0
POLR2G 1063.0 -12103.0
POLR2H -12591.0 -11738.0
POLR2I -5956.0 -15772.0
POLR2J -11626.0 -4910.0
POLR2K -1330.0 590.0
POLR2L -16149.0 -16420.0
RARA -10604.0 -9543.0
RARB -7281.0 -5586.0
RARG -11925.0 -5934.0
RBBP4 -9690.0 -15408.0
RBBP5 -12137.0 -1239.0
RXRA -6530.0 -1218.0
SUZ12 -12029.0 -10907.0
WDR5 -12951.0 -3421.0
YY1 -16108.0 -12034.0
ZNF335 -2469.0 -11704.0



REACTOME_NEDDYLATION

REACTOME_NEDDYLATION
metric value
setSize 233
pMANOVA 1.24e-05
p.adjustMANOVA 0.000454
s.dist 0.19
s.Estill -0.0607
s.Novakovic -0.18
p.Estill 0.11
p.Novakovic 2.18e-06




Top 20 genes
Gene Estill Novakovic
NEURL2 -16332 -16632
KCTD6 -15793 -16502
KCTD7 -15612 -16307
PSMA7 -15238 -16097
UBA3 -15541 -15740
PSMD1 -15755 -15264
SOCS2 -13731 -17078
FBXL3 -15085 -14438
KLHL11 -14392 -15120
PSMB2 -15087 -14324
FBXL15 -14627 -14552
FBXL12 -13018 -16165
FEM1A -13227 -15258
CISH -12548 -15728
FBXO4 -15943 -11926
FBXW7 -13298 -13607
FBXL5 -12749 -14140
PALB2 -12055 -14494
BTBD6 -13710 -12731
FBXO30 -10281 -16762

Click HERE to show all gene set members

All member genes
Estill Novakovic
ANKRD9 -7892 -10569
ASB1 -1235 -4580
ASB10 -14072 -5200
ASB13 -2473 -8600
ASB14 694 -11373
ASB15 479 -6185
ASB16 -6912 -5686
ASB18 -2226 -1579
ASB2 -9442 -2012
ASB3 -5310 -8183
ASB4 2196 -1841
ASB5 -16095 -9100
ASB6 -4727 -5688
ASB7 -2419 -7083
ASB8 -9288 -9220
BIRC5 -509 -2514
BRCA1 2021 628
BTBD1 -13443 -11526
BTBD6 -13710 -12731
BTRC -8741 -7184
CAND1 -6817 -9259
CCDC8 -6828 -2013
CCNF -3247 -5612
CDKN1A -7625 -12022
CISH -12548 -15728
COMMD1 -5113 320
COMMD10 -14048 -3215
COMMD2 -7309 -15624
COMMD3 -12696 -5634
COMMD4 -11961 -10079
COMMD5 -15239 -7422
COMMD6 -451 -14630
COMMD7 -12043 -9329
COMMD8 -10056 -7396
COMMD9 -6116 -5082
COP1 -12587 -4949
COPS2 -5715 -14728
COPS3 -14394 -3804
COPS4 -11652 -1767
COPS5 -7073 -4587
COPS6 -7846 -16853
COPS7A -10631 -9011
COPS7B -8464 -10839
COPS8 -8804 -4570
CUL1 -2215 449
CUL2 -3906 -4879
CUL3 -14992 -6223
CUL4A -6621 -10823
CUL5 -843 -13119
CUL7 -3055 -10083
CUL9 -8028 -4242
DCAF10 -4617 -16156
DCAF11 -13538 -8387
DCAF13 -9156 -5558
DCAF16 -6837 -13033
DCAF17 -10819 -15763
DCAF4 -11366 -4306
DCAF5 -7541 -5900
DCAF6 -11726 -12663
DCAF7 -208 -16268
DCAF8 -300 -14064
DCUN1D1 -9799 -9657
DCUN1D2 332 -3918
DCUN1D3 -3663 -14022
DCUN1D4 -2776 -15180
DCUN1D5 -9577 -10562
DDA1 -6172 -10729
DDB1 -3208 -12221
DDB2 -3131 -10737
DPP3 -15648 -6513
DTL -2147 -10668
ELOB -10647 -14069
ELOC -661 -10616
EPAS1 -2485 -8281
ERCC8 -6055 -4451
FBXL12 -13018 -16165
FBXL13 -3363 -10192
FBXL14 -8001 -4178
FBXL15 -14627 -14552
FBXL16 -7342 -6082
FBXL18 -3865 -1826
FBXL19 -6424 -9915
FBXL20 -16016 -6383
FBXL22 -9591 -14869
FBXL3 -15085 -14438
FBXL4 -13281 -6552
FBXL5 -12749 -14140
FBXL7 -618 -4837
FBXL8 -10674 -14990
FBXO10 245 -2014
FBXO11 -12169 -4458
FBXO15 -3353 -8878
FBXO17 -10324 -11787
FBXO2 -14249 -6703
FBXO21 -7794 -8178
FBXO22 -6083 -8731
FBXO27 -15881 -2987
FBXO30 -10281 -16762
FBXO31 -10323 -10703
FBXO32 -10663 -12770
FBXO4 -15943 -11926
FBXO40 -9 -5723
FBXO41 -4231 -134
FBXO44 -13523 23
FBXO6 -8972 -15198
FBXO7 -10825 -13283
FBXO9 -13450 -10603
FBXW10 1610 -9749
FBXW11 -2863 -8621
FBXW12 -191 -2608
FBXW2 -11571 -11821
FBXW4 -3900 -10605
FBXW5 -5600 -15276
FBXW7 -13298 -13607
FBXW8 651 -8606
FBXW9 -14054 -7302
FEM1A -13227 -15258
FEM1B -1019 -10671
FEM1C -6019 -15855
GAN -1814 -6556
GPS1 -14920 -11279
HIF1A -8609 -13639
HIF3A -4986 -4098
KBTBD6 -604 -13292
KBTBD7 -7694 -10371
KBTBD8 -2622 -13598
KCTD6 -15793 -16502
KCTD7 -15612 -16307
KEAP1 -9462 -12683
KLHL11 -14392 -15120
KLHL2 -7334 -9277
KLHL20 -8702 -14496
KLHL21 -8261 -6666
KLHL22 -6799 -10735
KLHL25 -5767 -10393
KLHL3 -2499 -4411
KLHL42 -7230 -3198
KLHL5 -7215 -15968
KLHL9 -3267 -15897
LMO7 -200 -8053
LRR1 -12468 -8236
LRRC41 -8084 -10466
MUL1 -8575 -11873
NAE1 -8521 -16904
NEDD8 -3301 -13380
NEURL2 -16332 -16632
NFE2L2 -7505 -15009
NPLOC4 -6167 -2163
NUB1 -7941 -6916
OBSL1 -5730 -6580
PALB2 -12055 -14494
PSMA1 -8781 -2177
PSMA2 -7391 -13190
PSMA3 -543 -12585
PSMA4 -1489 -11130
PSMA5 -5612 -12086
PSMA6 -5453 -7068
PSMA7 -15238 -16097
PSMA8 -12998 1341
PSMB1 -7998 -12452
PSMB10 1546 -12645
PSMB11 -7675 461
PSMB2 -15087 -14324
PSMB3 -2943 -16574
PSMB4 -3092 -17193
PSMB5 -2173 -13304
PSMB6 -1270 -15778
PSMB7 1688 1166
PSMB8 251 -10098
PSMB9 -4477 -14712
PSMC1 -2414 -13145
PSMC2 -315 -2310
PSMC3 -7461 -17123
PSMC4 459 -4407
PSMC5 -9725 -12293
PSMC6 -7301 332
PSMD1 -15755 -15264
PSMD11 -6796 -15996
PSMD12 -13229 -1837
PSMD13 -9340 -12191
PSMD14 -9752 -14404
PSMD2 -5101 -4469
PSMD3 -6030 -12489
PSMD4 -6049 -14518
PSMD5 2564 -8724
PSMD6 -5979 -12939
PSMD7 -12233 -5710
PSMD8 -9781 -13888
PSMD9 -11408 -10645
PSME1 -9760 -16962
PSME2 67 -15711
PSME3 -4965 -13719
PSME4 -13130 -13058
PSMF1 -12443 -3758
PUM2 -526 -5447
RBBP5 -12137 -1239
RBX1 -6001 -10254
RNF7 -15861 -4714
RPS27A -11481 -2147
SEM1 -1388 -14801
SENP8 -12001 -10406
SKP1 -9613 -15257
SKP2 -3788 -6780
SOCS2 -13731 -17078
SOCS3 -8896 -17163
SOCS5 -10767 -6126
SOCS6 -4942 -15727
SPSB1 -5094 -2850
SPSB2 -7743 -17169
SPSB3 -9934 -5937
SPSB4 -12107 -5718
SQSTM1 -10407 -9268
TULP4 1813 -4699
UBA3 -15541 -15740
UBA52 -10894 -4996
UBB -12784 -8060
UBC -11566 -692
UBD 971 1249
UBE2D1 -9905 -15085
UBE2D2 -10137 -16684
UBE2D3 -4713 -14451
UBE2F -12892 -7280
UBE2M -12213 -9760
UBXN7 -12544 -1810
UCHL3 -1957 -12712
UFD1 -7661 -1409
VCP -6950 -13469
VHL -9255 -285
WDR5 -12951 -3421
WDTC1 -4623 -11975
WSB1 -731 -16402
WSB2 -4051 -6180
ZBTB16 -3915 -3363



REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL

REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL
metric value
setSize 130
pMANOVA 1.82e-05
p.adjustMANOVA 0.000651
s.dist 0.245
s.Estill 0.0603
s.Novakovic 0.237
p.Estill 0.235
p.Novakovic 2.99e-06




Top 20 genes
Gene Estill Novakovic
GYPB 2659 1502
PSG8 1505 1813
PSG2 2013 1155
NRAS 1967 1159
MMP1 2164 674
CD84 2108 241
JAML 1189 76
F2 55 706

Click HERE to show all gene set members

All member genes
Estill Novakovic
ANGPT1 827 -11
ANGPT2 -2888 -2184
ANGPT4 -12918 -3802
APOB 340 -10566
ATP1B1 -6152 -5490
ATP1B2 -560 -16255
ATP1B3 -8891 -1048
BSG -4193 -9689
CAV1 -6955 -12026
CD177 -11239 -1343
CD2 -8602 -3955
CD244 -2922 -5950
CD44 -230 -10201
CD47 -11141 -8495
CD48 -5451 -6114
CD58 -7067 -5619
CD74 -8252 -2282
CD84 2108 241
CEACAM1 -4682 274
CEACAM3 -5905 -91
CEACAM5 -7513 826
CEACAM6 -6631 -908
CEACAM8 -15552 313
COL1A1 -6605 -9851
COL1A2 -6107 -9390
CXADR -12256 -7629
DOK2 -9215 1234
EPCAM -2655 -10927
ESAM -6340 -12971
F11R -3899 -11810
F2 55 706
FCAMR 1307 -11695
FCER1G -6888 800
FN1 -3373 -11200
FYN -763 -10108
GLG1 -7950 -2620
GP6 -4722 214
GPC1 -11109 -7559
GRB14 -8919 -4864
GRB2 -2312 -10356
GRB7 -10381 -2192
GYPB 2659 1502
GYPC -552 -4007
HRAS -12530 -5028
IGLL1 -13172 1199
INPP5D -1122 -2788
ITGA3 -10271 -12785
ITGA4 -15859 -12983
ITGA5 -8805 -1201
ITGA6 -12470 -10580
ITGAL -2798 712
ITGAM -4027 -6906
ITGAV -13806 -8462
ITGAX -6552 -7032
ITGB1 -8035 -14961
ITGB2 -5999 -349
ITGB3 236 -7170
JAM2 456 -11457
JAM3 -3101 -7549
JAML 1189 76
KRAS -9621 -16093
LCK -1772 -3483
LYN -8344 -1989
MAG -11019 75
MERTK -2725 -2984
MIF -10718 -16521
MMP1 2164 674
NRAS 1967 1159
OLR1 2044 -1997
PECAM1 544 -6844
PF4 -583 783
PF4V1 -7792 -8102
PICK1 -2537 -5819
PIK3CA -6368 -15554
PIK3CB 493 -16285
PIK3R1 -6866 -8817
PIK3R2 -10117 -11401
PLCG1 -16139 -11621
PPIA -10000 -12232
PPIL2 -8250 -6840
PROC -3877 63
PROCR -15052 -2740
PROS1 -13923 -4088
PSG1 -15219 1573
PSG11 -7504 1312
PSG2 2013 1155
PSG3 -11927 1841
PSG4 -16416 1654
PSG5 -3417 990
PSG6 -14858 1865
PSG7 -16319 -14530
PSG8 1505 1813
PSG9 -3457 -257
PTPN11 -9705 -9863
PTPN6 -16071 -1802
SDC1 -14370 -9666
SDC2 -5455 -13416
SDC3 -14944 -13897
SDC4 -7190 -3608
SELE -523 -9601
SELL -658 1207
SELP 2338 -4308
SELPLG -250 -2266
SHC1 -5102 -9832
SIRPA -11534 -6070
SIRPG -3262 -408
SLC16A1 -7753 -6884
SLC16A3 -14164 -2139
SLC16A8 -11303 -1046
SLC3A2 -8498 -4035
SLC7A10 -1762 -16660
SLC7A11 1900 -8846
SLC7A5 -11651 -958
SLC7A6 -11645 -3407
SLC7A7 426 -781
SLC7A8 -5078 -1710
SLC7A9 -7035 -8519
SOS1 -10061 -5272
SPN -13491 -7110
SRC -8945 -2260
TEK 1320 -916
TGFB1 -11372 -5923
THBD -14404 -14445
TNFRSF10A -2009 -12704
TNFRSF10B -10062 1321
TNFRSF10D -5365 -4909
TREM1 -1674 -4003
VPREB1 -1520 -7189
VPREB3 -2155 409
YES1 -2428 -15973



REACTOME_MITOTIC_G1_PHASE_AND_G1_S_TRANSITION

REACTOME_MITOTIC_G1_PHASE_AND_G1_S_TRANSITION
metric value
setSize 145
pMANOVA 1.9e-05
p.adjustMANOVA 0.000663
s.dist 0.241
s.Estill -0.0982
s.Novakovic -0.22
p.Estill 0.0413
p.Novakovic 4.73e-06




Top 20 genes
Gene Estill Novakovic
E2F1 -16127.0 -16773
CDKN2B -15666.0 -17173
DBF4 -15835.5 -16964
CDKN2D -14848.0 -16781
CDKN1C -15390.0 -16189
PSMA7 -15238.0 -16097
MCM4 -14468.0 -16835
PSMD1 -15755.0 -15264
CCNE1 -14226.0 -16873
PPP2CA -16303.0 -14663
PCNA -15776.0 -14982
FBXO5 -15003.0 -15440
CDT1 -15570.0 -14862
PSMB2 -15087.0 -14324
POLE4 -14979.0 -14320
CDKN1B -15950.0 -12998
WEE1 -13550.0 -14529
CDK4 -12590.0 -14349
ORC6 -10847.0 -16383
PSME1 -9760.0 -16962

Click HERE to show all gene set members

All member genes
Estill Novakovic
ABL1 -712.0 -2410
AKT1 -6145.0 -2432
AKT2 -12142.0 -6370
AKT3 -835.0 -5588
CABLES1 -9757.0 -8072
CCNA1 -11907.0 -12984
CCNA2 -6087.0 -16501
CCNB1 -15812.0 -8791
CCND1 -3494.0 -11443
CCND2 -9651.0 -15597
CCND3 -13014.0 -8722
CCNE1 -14226.0 -16873
CCNE2 -10192.0 -8331
CCNH -7680.0 -16219
CDC25A -9632.0 -11288
CDC45 -6700.0 80
CDC6 -9764.0 -8910
CDC7 -9686.0 -12389
CDK1 -629.5 -12551
CDK2 -241.0 -10000
CDK4 -12590.0 -14349
CDK6 -7466.0 -5435
CDK7 -11455.0 -8357
CDKN1A -7625.0 -12022
CDKN1B -15950.0 -12998
CDKN1C -15390.0 -16189
CDKN2A -13143.0 -1475
CDKN2B -15666.0 -17173
CDKN2C -9649.0 -15409
CDKN2D -14848.0 -16781
CDT1 -15570.0 -14862
CKS1B -2079.0 -12778
CUL1 -2215.0 449
DBF4 -15835.5 -16964
DHFR -5630.0 -14689
DYRK1A -9208.0 -5694
E2F1 -16127.0 -16773
E2F2 -13924.0 -7662
E2F3 -4245.0 -3475
E2F4 -12111.0 -13562
E2F5 -13411.0 -7919
E2F6 -5691.0 -3256
FBXO5 -15003.0 -15440
GMNN -2029.0 -11012
HDAC1 -9758.0 -7989
JAK2 -1045.0 -6197
LIN37 248.0 -14414
LIN52 -4993.0 -6014
LIN54 -14648.0 -2300
LIN9 -14550.0 -8492
LYN -8344.0 -1989
MAX -6413.0 -8827
MCM10 -909.0 -8152
MCM2 -1986.0 -8659
MCM3 -5522.0 -10547
MCM4 -14468.0 -16835
MCM5 -1200.0 -8591
MCM6 -11808.0 -8449
MCM7 -8495.0 -8481
MCM8 -6147.0 -12690
MNAT1 -2305.0 547
MYBL2 -4276.0 -7558
MYC -9179.0 -13967
ORC1 -5516.0 -284
ORC2 -128.0 -11753
ORC3 -10220.0 -14587
ORC4 -14431.0 -9786
ORC5 -10623.0 -6933
ORC6 -10847.0 -16383
PCNA -15776.0 -14982
POLA2 -11026.0 -12985
POLE -6579.0 -2548
POLE2 -10276.0 -11861
POLE3 -7721.0 -8097
POLE4 -14979.0 -14320
PPP2CA -16303.0 -14663
PPP2CB -790.0 302
PPP2R1A -5112.0 -15337
PPP2R1B -6245.0 -9456
PPP2R2A -14638.0 -5917
PRIM1 -3625.0 -12956
PRIM2 -1166.0 -3820
PSMA1 -8781.0 -2177
PSMA2 -7391.0 -13190
PSMA3 -543.0 -12585
PSMA4 -1489.0 -11130
PSMA5 -5612.0 -12086
PSMA6 -5453.0 -7068
PSMA7 -15238.0 -16097
PSMB1 -7998.0 -12452
PSMB10 1546.0 -12645
PSMB2 -15087.0 -14324
PSMB3 -2943.0 -16574
PSMB4 -3092.0 -17193
PSMB5 -2173.0 -13304
PSMB6 -1270.0 -15778
PSMB7 1688.0 1166
PSMB8 251.0 -10098
PSMB9 -4477.0 -14712
PSMC1 -2414.0 -13145
PSMC2 -315.0 -2310
PSMC3 -7461.0 -17123
PSMC4 459.0 -4407
PSMC5 -9725.0 -12293
PSMC6 -7301.0 332
PSMD1 -15755.0 -15264
PSMD11 -6796.0 -15996
PSMD12 -13229.0 -1837
PSMD13 -9340.0 -12191
PSMD14 -9752.0 -14404
PSMD2 -5101.0 -4469
PSMD3 -6030.0 -12489
PSMD4 -6049.0 -14518
PSMD5 2564.0 -8724
PSMD6 -5979.0 -12939
PSMD7 -12233.0 -5710
PSMD8 -9781.0 -13888
PSMD9 -11408.0 -10645
PSME1 -9760.0 -16962
PSME2 67.0 -15711
PSME3 -4965.0 -13719
PSMF1 -12443.0 -3758
PTK6 -14982.0 -2393
RB1 -9395.0 -7632
RBBP4 -9690.0 -15408
RBL1 823.0 -5072
RBL2 -7303.0 -11548
RPA1 1482.0 -2054
RPA2 -6976.0 -8172
RPA3 -13260.0 -8291
RPS27A -11481.0 -2147
RRM2 -10442.0 -8505
SEM1 -1388.0 -14801
SKP1 -9613.0 -15257
SKP2 -3788.0 -6780
SRC -8945.0 -2260
TFDP1 -507.0 -45
TFDP2 -14013.0 -2679
TK1 -4756.0 -10019
TOP2A -4473.0 -4314
TYMS -9594.0 -16610
UBA52 -10894.0 -4996
UBB -12784.0 -8060
UBC -11566.0 -692
WEE1 -13550.0 -14529



REACTOME_MITOTIC_PROMETAPHASE

REACTOME_MITOTIC_PROMETAPHASE
metric value
setSize 194
pMANOVA 2.02e-05
p.adjustMANOVA 0.000684
s.dist 0.204
s.Estill -0.0663
s.Novakovic -0.193
p.Estill 0.112
p.Novakovic 3.64e-06




Top 20 genes
Gene Estill Novakovic
NUP37 -15153 -17285
MAD2L1 -14859 -17139
CDCA5 -15196 -16601
SMC3 -14879 -16404
TUBG1 -16375 -14891
TUBA1B -14029 -17230
CENPO -14764 -16262
PPP2CA -16303 -14663
CEP135 -16264 -14394
NUF2 -14033 -15760
PPP2R5D -13597 -16200
CEP43 -13278 -16552
WAPL -15001 -14312
CEP76 -12726 -16607
NUDC -14374 -13884
HAUS2 -13309 -14657
MIS12 -11240 -17203
CENPT -13891 -13739
DYNLL2 -13828 -13633
CDCA8 -11699 -15979

Click HERE to show all gene set members

All member genes
Estill Novakovic
ACTR1A -10774.0 -9995
AHCTF1 -2570.0 -3624
AKAP9 -11760.0 -8323
ALMS1 -10177.0 -1025
AURKB -585.0 -2715
B9D2 -6475.0 -5577
BIRC5 -509.0 -2514
BUB1 -406.0 -13771
BUB1B -2372.0 -6560
BUB3 -3718.0 -13578
CCNB1 -15812.0 -8791
CCNB2 -5698.0 -12010
CCP110 -7242.0 -11338
CDC20 -14422.0 -10269
CDCA5 -15196.0 -16601
CDCA8 -11699.0 -15979
CDK1 -629.5 -12551
CDK5RAP2 866.0 -2873
CENPA -6563.0 -11218
CENPC -2493.0 -14292
CENPE -9573.0 -14208
CENPF -1734.0 -5756
CENPH -2153.0 -17067
CENPJ -3229.0 -6985
CENPK -3128.5 -16484
CENPL -3296.0 -14202
CENPM -13815.0 -6658
CENPN -5955.0 -11949
CENPO -14764.0 -16262
CENPP 1162.0 -12025
CENPQ -313.0 -6294
CENPS -7432.0 -6760
CENPT -13891.0 -13739
CENPU -13118.0 -12622
CEP131 -3422.0 -4824
CEP135 -16264.0 -14394
CEP152 -3924.0 -12738
CEP164 -13.0 -12119
CEP192 -5821.0 -2921
CEP250 -7889.0 -8951
CEP290 -346.0 -14952
CEP41 -7749.0 -15982
CEP43 -13278.0 -16552
CEP57 -15253.0 -12008
CEP63 -12858.0 -11039
CEP70 -8386.0 -8265
CEP72 -52.0 -4610
CEP76 -12726.0 -16607
CEP78 -11770.0 -9754
CKAP5 -7709.0 -13566
CLASP1 -368.0 -10453
CLASP2 -14327.0 -9568
CLIP1 -2981.0 -8081
CNTRL -4976.0 -2353
CSNK1D -10315.0 -2827
CSNK1E -12689.0 -11824
CSNK2A1 -10932.0 -4915
CSNK2A2 -15748.0 -7535
CSNK2B -367.0 -14595
DCTN1 69.0 -10034
DCTN2 -6153.0 -1119
DCTN3 -12480.0 -10976
DSN1 -11787.0 -7717
DYNC1H1 48.0 -3145
DYNC1I1 -7317.0 -6097
DYNC1I2 1732.0 -12829
DYNC1LI1 -11159.0 -13138
DYNC1LI2 -12760.0 -7326
DYNLL1 -11160.0 -14050
DYNLL2 -13828.0 -13633
EML4 -12051.0 -11469
HAUS1 -4546.0 -13080
HAUS2 -13309.0 -14657
HAUS3 -14922.0 -6957
HAUS4 -13307.0 -4175
HAUS5 -10024.0 -12724
HAUS6 -5085.0 -12244
HAUS8 -8315.0 -10096
HSP90AA1 -13375.0 -9820
INCENP -3511.0 -5422
ITGB3BP -11307.0 -12811
KIF18A -11259.0 -13594
KIF2A -3632.0 -14056
KIF2B 1804.0 1019
KIF2C -5345.0 -2415
KNL1 -5912.0 -5397
KNTC1 1079.0 -10240
MAD1L1 -2331.0 -1491
MAD2L1 -14859.0 -17139
MAPRE1 -7165.0 -1431
MIS12 -11240.0 -17203
MZT1 -6708.0 -11391
MZT2A -11036.0 -14936
MZT2B -4632.0 -14385
NCAPD2 -2535.0 -716
NCAPG -9210.0 -13713
NCAPH -11798.0 -14186
NDC80 -4561.0 -16763
NDE1 -5341.0 -4338
NDEL1 -13160.0 -13879
NEDD1 -5736.0 -2444
NEK2 -2328.0 -10364
NEK6 -6875.0 -128
NEK7 -8135.0 -6091
NEK9 -10302.0 -14259
NINL -11999.0 -5565
NME7 293.5 -7268
NSL1 -7434.0 -15145
NUDC -14374.0 -13884
NUF2 -14033.0 -15760
NUMA1 -6928.0 -6650
NUP107 -7236.0 -8001
NUP133 -2470.0 -9143
NUP160 -11625.0 -12148
NUP37 -15153.0 -17285
NUP43 -6734.0 -13552
NUP85 -4129.0 -11356
NUP98 -8145.0 -10870
ODF2 -5350.0 -8504
PAFAH1B1 -7252.0 -9774
PCM1 -9358.0 -12737
PCNT -6214.0 -5445
PDS5A -5166.0 -9013
PDS5B -5500.0 -6377
PLK1 -6031.0 -5485
PLK4 -7554.0 -13381
PMF1 -8086.0 -9424
PPP1CC -14817.0 -9753
PPP2CA -16303.0 -14663
PPP2CB -790.0 302
PPP2R1A -5112.0 -15337
PPP2R1B -6245.0 -9456
PPP2R5A -14844.0 -2972
PPP2R5B -6416.0 -16175
PPP2R5C -2004.0 -7658
PPP2R5D -13597.0 -16200
PPP2R5E -6877.0 -9033
PRKACA -15621.0 -10373
PRKAR2B -8749.0 -9071
RAD21 -13034.0 -4206
RANBP2 -8430.0 -15721
RANGAP1 -7181.0 -12265
RCC2 -5320.0 -5307
RPS27 1722.0 -11381
SDCCAG8 -4661.0 -3633
SEC13 -8604.0 -10471
SEH1L -8901.0 -14935
SFI1 -12444.0 -11569
SGO1 -4675.0 -4366
SGO2 -1842.0 -8446
SKA1 -6465.0 -16444
SKA2 -5163.0 -5832
SMC2 -6739.0 -8249
SMC3 -14879.0 -16404
SMC4 -14508.0 -9211
SPC24 -11068.0 -15981
SPC25 -3265.0 -2763
SPDL1 -5198.0 -9012
SSNA1 -5964.0 -8575
STAG1 -4192.0 -10829
TAOK1 -12592.0 -8943
TUBA1A -2200.0 -6514
TUBA1B -14029.0 -17230
TUBA1C -3384.0 -9518
TUBA3C -2572.0 1353
TUBA3D 667.0 1328
TUBA3E -557.0 1710
TUBA4A -14192.0 -8929
TUBA4B -12730.0 -11735
TUBA8 -10422.0 -5063
TUBAL3 -1441.0 974
TUBB -4832.0 -14732
TUBB1 474.0 -2704
TUBB2A -9611.0 -15207
TUBB2B -3861.0 -15169
TUBB3 -8126.0 -15236
TUBB4A -7628.0 279
TUBB4B -1709.0 -4047
TUBB6 -10077.0 -1707
TUBB8 -5845.0 1599
TUBG1 -16375.0 -14891
TUBG2 -2182.0 -9317
TUBGCP2 -2326.0 -864
TUBGCP3 -11364.0 -8086
TUBGCP4 -14320.0 -6397
TUBGCP5 -5996.0 -13306
TUBGCP6 -5866.0 -11053
WAPL -15001.0 -14312
XPO1 -11418.0 -13329
YWHAE -7622.0 -13250
YWHAG -5540.0 -4226
ZW10 -1493.0 -10411
ZWILCH -15096.0 -2173
ZWINT -11659.0 -15238



REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE

REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE
metric value
setSize 228
pMANOVA 2.07e-05
p.adjustMANOVA 0.000684
s.dist 0.189
s.Estill -0.0636
s.Novakovic -0.178
p.Estill 0.0983
p.Novakovic 3.86e-06




Top 20 genes
Gene Estill Novakovic
NUP37 -15153 -17285
MAD2L1 -14859 -17139
CDCA5 -15196 -16601
PSMA7 -15238 -16097
SMC3 -14879 -16404
TUBA1B -14029 -17230
PSMD1 -15755 -15264
CENPO -14764 -16262
PPP2CA -16303 -14663
FBXO5 -15003 -15440
NUF2 -14033 -15760
PPP2R5D -13597 -16200
PSMB2 -15087 -14324
WAPL -15001 -14312
CHMP2B -13036 -15756
UBE2C -14095 -14424
VRK1 -14545 -13800
NUDC -14374 -13884
MIS12 -11240 -17203
CENPT -13891 -13739

Click HERE to show all gene set members

All member genes
Estill Novakovic
AHCTF1 -2570.0 -3624
ANAPC1 -2324.0 -5744
ANAPC10 -11343.0 -5816
ANAPC11 -15553.0 -3569
ANAPC15 -5573.0 -1354
ANAPC16 -3464.0 -3219
ANAPC2 -8367.0 -1213
ANAPC4 -11051.0 -6188
ANAPC5 -7613.0 -11860
ANAPC7 -6389.0 -4274
ANKLE2 -990.0 -8487
AURKB -585.0 -2715
B9D2 -6475.0 -5577
BANF1 -12198.0 -14222
BIRC5 -509.0 -2514
BUB1 -406.0 -13771
BUB1B -2372.0 -6560
BUB3 -3718.0 -13578
CC2D1B -2031.0 -14994
CCNB1 -15812.0 -8791
CCNB2 -5698.0 -12010
CDC16 -3120.0 -6337
CDC20 -14422.0 -10269
CDC23 -4732.0 -5268
CDC26 -5432.0 -868
CDC27 -8038.0 -11129
CDCA5 -15196.0 -16601
CDCA8 -11699.0 -15979
CDK1 -629.5 -12551
CENPA -6563.0 -11218
CENPC -2493.0 -14292
CENPE -9573.0 -14208
CENPF -1734.0 -5756
CENPH -2153.0 -17067
CENPK -3128.5 -16484
CENPL -3296.0 -14202
CENPM -13815.0 -6658
CENPN -5955.0 -11949
CENPO -14764.0 -16262
CENPP 1162.0 -12025
CENPQ -313.0 -6294
CENPS -7432.0 -6760
CENPT -13891.0 -13739
CENPU -13118.0 -12622
CHMP2A -6394.0 -196
CHMP2B -13036.0 -15756
CHMP3 -7699.0 8
CHMP4A -8786.0 -640
CHMP4B -15007.0 -3831
CHMP4C -11740.0 -15669
CHMP6 -13294.0 -8756
CHMP7 -3337.0 -3187
CKAP5 -7709.0 -13566
CLASP1 -368.0 -10453
CLASP2 -14327.0 -9568
CLIP1 -2981.0 -8081
DSN1 -11787.0 -7717
DYNC1H1 48.0 -3145
DYNC1I1 -7317.0 -6097
DYNC1I2 1732.0 -12829
DYNC1LI1 -11159.0 -13138
DYNC1LI2 -12760.0 -7326
DYNLL1 -11160.0 -14050
DYNLL2 -13828.0 -13633
ESPL1 -8703.0 -4634
FBXO5 -15003.0 -15440
INCENP -3511.0 -5422
IST1 -2314.0 -15295
ITGB3BP -11307.0 -12811
KIF18A -11259.0 -13594
KIF2A -3632.0 -14056
KIF2B 1804.0 1019
KIF2C -5345.0 -2415
KNL1 -5912.0 -5397
KNTC1 1079.0 -10240
KPNB1 -14539.0 -12059
LBR -14393.0 -367
LEMD2 -12960.0 -11635
LEMD3 -4333.0 -6107
LMNA -8291.0 -4922
LMNB1 -12895.0 -9972
MAD1L1 -2331.0 -1491
MAD2L1 -14859.0 -17139
MAPRE1 -7165.0 -1431
MIS12 -11240.0 -17203
NDC1 -11478.0 -8778
NDC80 -4561.0 -16763
NDE1 -5341.0 -4338
NDEL1 -13160.0 -13879
NSL1 -7434.0 -15145
NUDC -14374.0 -13884
NUF2 -14033.0 -15760
NUP107 -7236.0 -8001
NUP133 -2470.0 -9143
NUP155 -12129.0 -15214
NUP160 -11625.0 -12148
NUP188 -7877.0 -15187
NUP205 -7637.0 -436
NUP35 -1428.0 -7296
NUP37 -15153.0 -17285
NUP43 -6734.0 -13552
NUP54 -12929.0 -7747
NUP58 -9205.0 -15350
NUP62 -3466.0 -2332
NUP85 -4129.0 -11356
NUP93 -3140.0 -9015
NUP98 -8145.0 -10870
PAFAH1B1 -7252.0 -9774
PDS5A -5166.0 -9013
PDS5B -5500.0 -6377
PLK1 -6031.0 -5485
PMF1 -8086.0 -9424
POM121 -13119.0 -11642
PPP1CC -14817.0 -9753
PPP2CA -16303.0 -14663
PPP2CB -790.0 302
PPP2R1A -5112.0 -15337
PPP2R1B -6245.0 -9456
PPP2R2A -14638.0 -5917
PPP2R5A -14844.0 -2972
PPP2R5B -6416.0 -16175
PPP2R5C -2004.0 -7658
PPP2R5D -13597.0 -16200
PPP2R5E -6877.0 -9033
PSMA1 -8781.0 -2177
PSMA2 -7391.0 -13190
PSMA3 -543.0 -12585
PSMA4 -1489.0 -11130
PSMA5 -5612.0 -12086
PSMA6 -5453.0 -7068
PSMA7 -15238.0 -16097
PSMA8 -12998.0 1341
PSMB1 -7998.0 -12452
PSMB10 1546.0 -12645
PSMB11 -7675.0 461
PSMB2 -15087.0 -14324
PSMB3 -2943.0 -16574
PSMB4 -3092.0 -17193
PSMB5 -2173.0 -13304
PSMB6 -1270.0 -15778
PSMB7 1688.0 1166
PSMB8 251.0 -10098
PSMB9 -4477.0 -14712
PSMC1 -2414.0 -13145
PSMC2 -315.0 -2310
PSMC3 -7461.0 -17123
PSMC4 459.0 -4407
PSMC5 -9725.0 -12293
PSMC6 -7301.0 332
PSMD1 -15755.0 -15264
PSMD11 -6796.0 -15996
PSMD12 -13229.0 -1837
PSMD13 -9340.0 -12191
PSMD14 -9752.0 -14404
PSMD2 -5101.0 -4469
PSMD3 -6030.0 -12489
PSMD4 -6049.0 -14518
PSMD5 2564.0 -8724
PSMD6 -5979.0 -12939
PSMD7 -12233.0 -5710
PSMD8 -9781.0 -13888
PSMD9 -11408.0 -10645
PSME1 -9760.0 -16962
PSME2 67.0 -15711
PSME3 -4965.0 -13719
PSME4 -13130.0 -13058
PSMF1 -12443.0 -3758
PTTG1 -3508.0 -13806
RAD21 -13034.0 -4206
RAN -10662.0 -16269
RANBP2 -8430.0 -15721
RANGAP1 -7181.0 -12265
RCC1 -308.0 -2368
RCC2 -5320.0 -5307
RPS27 1722.0 -11381
RPS27A -11481.0 -2147
SEC13 -8604.0 -10471
SEH1L -8901.0 -14935
SEM1 -1388.0 -14801
SGO1 -4675.0 -4366
SGO2 -1842.0 -8446
SIRT2 -6884.0 -9850
SKA1 -6465.0 -16444
SKA2 -5163.0 -5832
SMC3 -14879.0 -16404
SPAST -15874.0 -9503
SPC24 -11068.0 -15981
SPC25 -3265.0 -2763
SPDL1 -5198.0 -9012
STAG1 -4192.0 -10829
SUMO1 -32.0 -9758
TAOK1 -12592.0 -8943
TMPO -15535.0 -8262
TNPO1 -12905.0 -8329
TUBA1A -2200.0 -6514
TUBA1B -14029.0 -17230
TUBA1C -3384.0 -9518
TUBA3C -2572.0 1353
TUBA3D 667.0 1328
TUBA3E -557.0 1710
TUBA4A -14192.0 -8929
TUBA4B -12730.0 -11735
TUBA8 -10422.0 -5063
TUBAL3 -1441.0 974
TUBB1 474.0 -2704
TUBB2A -9611.0 -15207
TUBB2B -3861.0 -15169
TUBB3 -8126.0 -15236
TUBB4A -7628.0 279
TUBB4B -1709.0 -4047
TUBB6 -10077.0 -1707
TUBB8 -5845.0 1599
UBA52 -10894.0 -4996
UBB -12784.0 -8060
UBC -11566.0 -692
UBE2C -14095.0 -14424
UBE2D1 -9905.0 -15085
UBE2E1 -7722.0 -8346
UBE2I -10552.0 -5939
UBE2S -10702.0 -8077
VPS4A -6364.0 -13269
VRK1 -14545.0 -13800
VRK2 -11405.0 -3325
WAPL -15001.0 -14312
XPO1 -11418.0 -13329
ZW10 -1493.0 -10411
ZWILCH -15096.0 -2173
ZWINT -11659.0 -15238



REACTOME_DNA_REPLICATION

REACTOME_DNA_REPLICATION
metric value
setSize 179
pMANOVA 2.12e-05
p.adjustMANOVA 0.000684
s.dist 0.213
s.Estill -0.0742
s.Novakovic -0.2
p.Estill 0.0871
p.Novakovic 4.09e-06




Top 20 genes
Gene Estill Novakovic
DBF4 -15835.5 -16964
H3C12 -15164.0 -17158
PSMA7 -15238.0 -16097
MCM4 -14468.0 -16835
PSMD1 -15755.0 -15264
CCNE1 -14226.0 -16873
PCNA -15776.0 -14982
CDT1 -15570.0 -14862
H2AX -13329.0 -16764
PSMB2 -15087.0 -14324
POLE4 -14979.0 -14320
H3-3A -13934.0 -14636
UBE2C -14095.0 -14424
H3C8 -15918.0 -12729
H2AZ2 -15177.0 -12968
KPNA1 -15937.0 -12138
H2BC26 -11379.0 -16861
H2AC8 -15265.0 -12472
ORC6 -10847.0 -16383
H3C2 -15289.0 -11553

Click HERE to show all gene set members

All member genes
Estill Novakovic
ANAPC1 -2324.0 -5744.0
ANAPC10 -11343.0 -5816.0
ANAPC11 -15553.0 -3569.0
ANAPC15 -5573.0 -1354.0
ANAPC16 -3464.0 -3219.0
ANAPC2 -8367.0 -1213.0
ANAPC4 -11051.0 -6188.0
ANAPC5 -7613.0 -11860.0
ANAPC7 -6389.0 -4274.0
CCNA1 -11907.0 -12984.0
CCNA2 -6087.0 -16501.0
CCNE1 -14226.0 -16873.0
CCNE2 -10192.0 -8331.0
CDC16 -3120.0 -6337.0
CDC23 -4732.0 -5268.0
CDC26 -5432.0 -868.0
CDC27 -8038.0 -11129.0
CDC45 -6700.0 80.0
CDC6 -9764.0 -8910.0
CDC7 -9686.0 -12389.0
CDK2 -241.0 -10000.0
CDT1 -15570.0 -14862.0
CUL1 -2215.0 449.0
DBF4 -15835.5 -16964.0
DNA2 -3490.0 -12624.0
FEN1 -3850.0 -9060.0
FZR1 -7455.0 -2900.0
GINS1 -5314.0 -15131.0
GINS2 -6809.0 -14649.0
GINS3 -306.0 -3695.0
GINS4 -2971.0 -1628.0
GMNN -2029.0 -11012.0
H2AC14 -740.0 -6291.0
H2AC18 -10109.5 -16821.5
H2AC19 -10109.5 -16821.5
H2AC20 -9365.0 -421.0
H2AC4 -8682.0 -7652.0
H2AC6 -3772.0 -14402.0
H2AC7 -10309.0 -3529.5
H2AC8 -15265.0 -12472.0
H2AJ -360.0 -16792.0
H2AX -13329.0 -16764.0
H2AZ1 -10477.0 -10825.0
H2AZ2 -15177.0 -12968.0
H2BC1 930.5 1414.0
H2BC10 -12140.0 -5784.0
H2BC11 -4716.0 -15808.0
H2BC12 -3961.0 -14793.0
H2BC13 -11400.0 761.0
H2BC14 -1609.0 -8267.0
H2BC15 -2744.0 -168.0
H2BC17 -16322.0 -3166.0
H2BC21 -8996.0 -6316.0
H2BC26 -11379.0 -16861.0
H2BC3 -15205.0 -10594.0
H2BC4 -10641.0 -8955.0
H2BC5 -9533.0 315.0
H2BC6 -15206.0 266.0
H2BC7 -11776.0 -3529.5
H2BC8 -15228.0 -8541.0
H2BC9 -9951.5 -12902.5
H3-3A -13934.0 -14636.0
H3-3B -9143.0 -13971.0
H3C1 -9230.0 -14629.0
H3C10 -3065.0 -374.0
H3C11 -7068.0 -13728.0
H3C12 -15164.0 -17158.0
H3C13 -4294.0 -15204.0
H3C2 -15289.0 -11553.0
H3C3 -6133.0 -14272.0
H3C4 -9971.0 -5667.0
H3C6 371.0 -17250.0
H3C7 -9951.5 -12902.5
H3C8 -15918.0 -12729.0
H4C1 -14459.0 -9617.0
H4C11 854.0 -16001.0
H4C12 -2120.0 -5312.0
H4C13 -334.0 -15402.0
H4C16 -7238.0 -8548.0
H4C2 -7763.0 -2343.0
H4C3 -5978.0 -7968.0
H4C4 -850.0 -16161.0
H4C5 -1971.0 -1886.0
H4C6 -9232.0 -16384.0
H4C8 -3484.0 -14606.0
H4C9 -10105.0 -17149.0
KPNA1 -15937.0 -12138.0
KPNA6 -1126.0 -1121.0
KPNB1 -14539.0 -12059.0
LIG1 -15008.0 -2042.0
MCM10 -909.0 -8152.0
MCM2 -1986.0 -8659.0
MCM3 -5522.0 -10547.0
MCM4 -14468.0 -16835.0
MCM5 -1200.0 -8591.0
MCM6 -11808.0 -8449.0
MCM7 -8495.0 -8481.0
MCM8 -6147.0 -12690.0
ORC1 -5516.0 -284.0
ORC2 -128.0 -11753.0
ORC3 -10220.0 -14587.0
ORC4 -14431.0 -9786.0
ORC5 -10623.0 -6933.0
ORC6 -10847.0 -16383.0
PCNA -15776.0 -14982.0
POLA2 -11026.0 -12985.0
POLD1 -4311.0 -6454.0
POLD2 -11066.0 470.0
POLD3 -5727.0 -13049.0
POLD4 -1289.0 -13917.0
POLE -6579.0 -2548.0
POLE2 -10276.0 -11861.0
POLE3 -7721.0 -8097.0
POLE4 -14979.0 -14320.0
PRIM1 -3625.0 -12956.0
PRIM2 -1166.0 -3820.0
PSMA1 -8781.0 -2177.0
PSMA2 -7391.0 -13190.0
PSMA3 -543.0 -12585.0
PSMA4 -1489.0 -11130.0
PSMA5 -5612.0 -12086.0
PSMA6 -5453.0 -7068.0
PSMA7 -15238.0 -16097.0
PSMA8 -12998.0 1341.0
PSMB1 -7998.0 -12452.0
PSMB10 1546.0 -12645.0
PSMB11 -7675.0 461.0
PSMB2 -15087.0 -14324.0
PSMB3 -2943.0 -16574.0
PSMB4 -3092.0 -17193.0
PSMB5 -2173.0 -13304.0
PSMB6 -1270.0 -15778.0
PSMB7 1688.0 1166.0
PSMB8 251.0 -10098.0
PSMB9 -4477.0 -14712.0
PSMC1 -2414.0 -13145.0
PSMC2 -315.0 -2310.0
PSMC3 -7461.0 -17123.0
PSMC4 459.0 -4407.0
PSMC5 -9725.0 -12293.0
PSMC6 -7301.0 332.0
PSMD1 -15755.0 -15264.0
PSMD11 -6796.0 -15996.0
PSMD12 -13229.0 -1837.0
PSMD13 -9340.0 -12191.0
PSMD14 -9752.0 -14404.0
PSMD2 -5101.0 -4469.0
PSMD3 -6030.0 -12489.0
PSMD4 -6049.0 -14518.0
PSMD5 2564.0 -8724.0
PSMD6 -5979.0 -12939.0
PSMD7 -12233.0 -5710.0
PSMD8 -9781.0 -13888.0
PSMD9 -11408.0 -10645.0
PSME1 -9760.0 -16962.0
PSME2 67.0 -15711.0
PSME3 -4965.0 -13719.0
PSME4 -13130.0 -13058.0
PSMF1 -12443.0 -3758.0
RBX1 -6001.0 -10254.0
RFC1 -11317.0 -9485.0
RFC2 -11390.0 -13410.0
RFC3 1547.0 -8638.0
RFC4 -12661.0 -13699.0
RFC5 -3459.0 -7830.0
RPA1 1482.0 -2054.0
RPA2 -6976.0 -8172.0
RPA3 -13260.0 -8291.0
RPS27A -11481.0 -2147.0
SEM1 -1388.0 -14801.0
SKP1 -9613.0 -15257.0
SKP2 -3788.0 -6780.0
UBA52 -10894.0 -4996.0
UBB -12784.0 -8060.0
UBC -11566.0 -692.0
UBE2C -14095.0 -14424.0
UBE2D1 -9905.0 -15085.0
UBE2E1 -7722.0 -8346.0
UBE2S -10702.0 -8077.0



Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] farver_2.1.1              beanplot_1.3.1           
##  [41] BiocFileCache_2.10.1      webshot_0.5.5            
##  [43] illuminaio_0.44.0         GenomicAlignments_1.38.0 
##  [45] jsonlite_1.8.8            multtest_2.58.0          
##  [47] ellipsis_0.3.2            survival_3.5-7           
##  [49] systemfonts_1.0.5         tools_4.3.2              
##  [51] progress_1.2.3            Rcpp_1.0.11              
##  [53] glue_1.6.2                SparseArray_1.2.2        
##  [55] xfun_0.41                 HDF5Array_1.30.0         
##  [57] withr_2.5.2               fastmap_1.1.1            
##  [59] rhdf5filters_1.14.1       fansi_1.0.6              
##  [61] openssl_2.1.1             caTools_1.18.2           
##  [63] digest_0.6.33             R6_2.5.1                 
##  [65] mime_0.12                 colorspace_2.1-0         
##  [67] biomaRt_2.58.0            RSQLite_2.3.4            
##  [69] utf8_1.2.4                tidyr_1.3.0              
##  [71] generics_0.1.3            data.table_1.14.10       
##  [73] rtracklayer_1.62.0        prettyunits_1.2.0        
##  [75] httr_1.4.7                htmlwidgets_1.6.4        
##  [77] S4Arrays_1.2.0            ggstats_0.5.1            
##  [79] pkgconfig_2.0.3           gtable_0.3.4             
##  [81] blob_1.2.4                siggenes_1.76.0          
##  [83] htmltools_0.5.7           scales_1.3.0             
##  [85] rstudioapi_0.15.0         knitr_1.45               
##  [87] tzdb_0.4.0                rjson_0.2.21             
##  [89] nlme_3.1-163              curl_5.2.0               
##  [91] org.Hs.eg.db_3.18.0       cachem_1.0.8             
##  [93] rhdf5_2.46.1              stringr_1.5.1            
##  [95] KernSmooth_2.23-22        AnnotationDbi_1.64.1     
##  [97] restfulr_0.0.15           GEOquery_2.70.0          
##  [99] pillar_1.9.0              grid_4.3.2               
## [101] reshape_0.8.9             vctrs_0.6.5              
## [103] promises_1.2.1            dbplyr_2.4.0             
## [105] xtable_1.8-4              evaluate_0.23            
## [107] readr_2.1.4               GenomicFeatures_1.54.1   
## [109] cli_3.6.2                 compiler_4.3.2           
## [111] Rsamtools_2.18.0          rlang_1.1.2              
## [113] crayon_1.5.2              rngtools_1.5.2           
## [115] labeling_0.4.3            nor1mix_1.3-2            
## [117] mclust_6.0.1              plyr_1.8.9               
## [119] stringi_1.8.3             viridisLite_0.4.2        
## [121] BiocParallel_1.36.0       assertthat_0.2.1         
## [123] topconfects_1.18.0        munsell_0.5.0            
## [125] Matrix_1.6-1.1            hms_1.1.3                
## [127] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [129] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [131] statmod_1.5.0             shiny_1.8.0              
## [133] highr_0.10                memoise_2.0.1            
## [135] bslib_0.6.1               bit_4.0.5

END of report